bluuebunny/crossref_metadata_2025 huggingface dataset:
Nano-and Micromotors Designed for Cancer Therapy
Authors: Sonntag Luisa , Simmchen Juliane , Magdanz Veronika
Published: September 2019

Research on nano- and micromotors has evolved into a frequently cited research area with innovative technology envisioned for one of current humanities’ most deadly problems: cancer. The development of cancer targeting drug delivery strategies involving nano-and micromotors has been a vibrant field of study over the past few years. This review aims at categorizing recent significant results, classifying them according to the employed propulsion mechanisms starting from chemically driven micromotors, to field driven and biohybrid approaches. In concluding remarks of section 2, we give an insight into shape changing micromotors that are envisioned to have a significant contribution. Finally, we critically discuss which important aspects still have to be addressed and which challenges still lie ahead of us.
Design of Peptidomimetic Functionalized Cholesterol Based Lipid Nanoparticles for Efficient Delivery of Therapeutic Nucleic Acids
Authors: Ehexige Ehexige , Ganbold Tsogzolmaa , Yu Xiang , Han Shuqin , Baigude Huricha
Published: September 2019

Lipid nanoparticles (LNP) are the most potent carriers for the delivery of nucleic acid-based therapeutics. The first FDA approved a short interfering RNA (siRNA) drug that uses a cationic LNP system for the delivery of siRNA against human transthyretin (hTTR). However, preparation of such LNP involves tedious multi-step synthesis with relatively low yields. In the present study, we synthesized cationic peptidomimetic functionalized cholesterol (denote Chorn) in straightforward chemical approaches with high yield. When formulated with helper lipids, Chorn LNPs complexed with siRNA to form nanoparticles with an average diameter of 150 nm to 200 nm. Chorn LNP mediated transfection of a green fluorescence protein (GFP) expressing plasmid resulted in 60% GFP positive cells. Moreover, Chorn LNP delivered siRNA against polo-like kinase 1 (Plk1), a disease related gene in cancer cells and efficiently suppressed the expression of the gene, resulting in significant morphological changes in the cell nuclei. Our data suggested that cholesterol based cationic LNP, prepared through a robust chemical strategy, may provide a promising siRNA delivery system.
A Multiple Target Positioning and Tracking System Behind Brick-Concrete Walls Using Multiple Monostatic IR-UWB Radars
Authors: Yoo Sungwon , Wang Dingyang , Seol Dong-Min , Lee Chulsoo , Chung Sungmoon , Cho Sung Ho
Published: September 2019

Recognizing and tracking the targets located behind walls through impulse radio ultra-wideband (IR-UWB) radar provides a significant advantage, as the characteristics of the IR-UWB radar signal enable it to penetrate obstacles. In this study, we design a through-wall radar system to estimate and track multiple targets behind a wall. The radar signal received through the wall experiences distortion, such as attenuation and delay, and the characteristics of the wall are estimated to compensate the distance error. In addition, unlike general cases, it is difficult to maintain a high detection rate and low false alarm rate in this through-wall radar application due to the attenuation and distortion caused by the wall. In particular, the generally used delay-and-sum algorithm is significantly affected by the motion of targets and distortion caused by the wall, rendering it difficult to obtain a good performance. Thus, we propose a novel method, which calculates the likelihood that a target exists in a certain location through a detection process. Unlike the delay-and-sum algorithm, this method does not use the radar signal directly. Simulations and experiments are conducted in different cases to show the validity of our through-wall radar system. The results obtained by using the proposed algorithm as well as delay-and-sum and trilateration are compared in terms of the detection rate, false alarm rate, and positioning error.
A Machine Learning Approach to Bridge-Damage Detection Using Responses Measured on a Passing Vehicle
Authors: Malekjafarian Abdollah , Golpayegani Fatemeh , Moloney Callum , Clarke Siobhán
Published: September 2019

This paper proposes a new two-stage machine learning approach for bridge damage detection using the responses measured on a passing vehicle. In the first stage, an artificial neural network (ANN) is trained using the vehicle responses measured from multiple passes (training data set) over a healthy bridge. The vehicle acceleration or Discrete Fourier Transform (DFT) spectrum of the acceleration is used. The vehicle response is predicted from its speed for multiple passes (monitoring data set) over the bridge. Root-mean-square error is used to calculate the prediction error, which indicates the differences between the predicted and measured responses for each passage. In the second stage of the proposed method, a damage indicator is defined using a Gaussian process that detects the changes in the distribution of the prediction errors. It is suggested that if the bridge condition is healthy, the distribution of the prediction errors will remain low. A recognizable change in the distribution might indicate a damage in the bridge. The performance of the proposed approach was evaluated using numerical case studies of vehicle–bridge interaction. It was demonstrated that the approach could successfully detect the damage in the presence of road roughness profile and measurement noise, even for low damage levels.
AEF: Adaptive En-Route Filtering to Extend Network Lifetime in Wireless Sensor Networks
Authors: Shahzad Muhammad K. , Islam S. M. Riazul , Kwak Kyung-Sup , Nkenyereye Lewis
Published: September 2019

Static sink-based wireless sensor networks (WSNs) suffer from an energy-hole problem. This incurs as the rate of energy consumption on sensor nodes around sinks and on critical paths is considerably faster. State-of-the-art en-routing filtering schemes save energy by countering false report injection attacks. In addition to their unique limitations, these schemes generally do not examine energy awareness in underlying routing. Mostly, these security methods are based on a fixed filtering capacity, unable to respond to changes in attack intensity. Therefore, these limitations cause network partition(s), exhibiting adverse effects on network lifetime. Extending network lifetime while preserving energy and security thus becomes an interesting challenge. In this article, we address the aforesaid shortcomings with the proposed adaptive en-route filtering (AEF) scheme. In energy-aware routing, the fitness function, which is used to select forwarding nodes, considers residual energy and other factors as opposed to distance only. In pre-deterministic key distribution, keys are distributed based on the consideration of having paths with a different number of verification nodes. This, consequently, permits us to have multiple paths with different security levels that can be exploited to counter different attack intensities. Taken together, the integration of the special fitness function with the new key distribution approach enables the AEF to adapt the underlying dynamic network conditions. The simulation experiments under different settings show significant improvements in network lifetime.
Reducing the Cost of Implementing Filters in LoRa Devices
Authors: Stewart Shania , Nguyen Ha H. , Barton Robert , Henry Jerome
Published: September 2019

This paper presents two methods to optimize LoRa (Low-Power Long-Range) devices so that implementing multiplier-less pulse shaping filters is more economical. Basic chirp waveforms can be generated more efficiently using the method of chirp segmentation so that only a quarter of the samples needs to be stored in the ROM. Quantization can also be applied to the basic chirp samples in order to reduce the number of unique input values to the filter, which in turn reduces the size of the lookup table for multiplier-less filter implementation. Various tests were performed on a simulated LoRa system in order to evaluate the impact of the quantization error on the system performance. By examining the occupied bandwidth, fast Fourier transform used for symbol demodulation, and bit-error rates, it is shown that even performing a high level of quantization does not cause significant performance degradation. Therefore, the memory requirements of LoRa devices can be significantly reduced by using the methods of chirp segmentation and quantization so as to improve the feasibility of implementing multiplier-less filters in LoRa devices.
Multi-Layer IoT Security Framework for Ambient Intelligence Environments
Authors: Bica Ion , Chifor Bogdan-Cosmin , Arseni Ștefan-Ciprian , Matei Ioana
Published: September 2019

Ambient intelligence is a new paradigm in the Internet of Things (IoT) world that brings smartness to living environments to make them more sensitive; adaptive; and personalized to human needs. A critical area where ambient intelligence can be used is health and social care; where it can improve and sustain the quality of life without increasing financial costs. The adoption of this new paradigm for health and social care largely depends on the technology deployed (sensors and wireless networks), the software used for decision-making and the security, privacy and reliability of the information. IoT sensors and wearables collect sensitive data and must respond in a near real-time manner to input changes. An IoT security framework is meant to offer the versatility and modularization needed to sustain such applications. Our framework was designed to easily integrate with different health and social care applications, separating security tasks from functional ones and being designed with independent modules for each layer (Cloud, gateway and IoT device), that offer functionalities relative to that layer.
Constant-Modulus-Waveform Design for Multiple-Target Detection in Colocated MIMO Radar
Authors: Liu Bingfan , Chen Baixiao , Yang Minglei
Published: September 2019

For improving the performance of multiple-target detection in a colocated multiple-input multiple-output (MIMO) radar system, a constant-modulus-waveform design method is presented in this paper. The proposed method consists of two steps: simultaneous multiple-transmit-beam design and constant-modulus-waveform design. In the first step, each transmit beam is controlled by an ideal orthogonal waveform and a weight vector. We optimized the weight vectors to maximize the detection probabilities of all targets or minimize the transmit power for the purpose of low intercept probability in the case of predefined worst detection probabilities. Various targets’ radar cross-section (RCS) fluctuation models were also considered in two optimization problems. Then, the optimal weight vectors multiplied by ideal orthogonal waveforms were a set of transmitted waveforms. However, those transmitted waveforms were not constant-modulus waveforms. In the second step, the transmitted waveforms obtained in the first step were mapped to constant-modulus waveforms by cyclic algorithm. Numerical examples are provided to show that the proposed constant-waveform design method could effectively achieve the desired transmit-beam pattern, and that the transmit-beam pattern could be adaptively adjusted according to prior information.
Empirical Formulas for Estimating Backscattering and Absorption Coefficients in Complex Waters from Remote-Sensing Reflectance Spectra and Examples of Their Application
Authors: Woźniak Sławomir B. , Darecki Mirosław , Sagan Sławomir
Published: September 2019

Many standard methods used for the remote sensing of ocean colour have been developed, though mainly for clean, open ocean waters. This means that they may not always be effective in complex waters potentially containing high concentrations of optically significant constituents. This paper presents new empirical formulas for estimating selected inherent optical properties of water from remote-sensing reflectance spectra Rrs(λ), derived, among other things, for waters with high concentrations of dissolved and suspended substances. These formulas include one for estimating the backscattering coefficient bb(620) directly from the magnitude of Rrs in the red part of the spectrum, and another for estimating the absorption coefficient a(440) from the hue angle α. The latter quantity represents the water’s colour as it might be perceived by the human eye (trichromatic colour vision); it is easily calculated from the shape of the Rrs spectrum. These new formulas are based on a combined dataset. Most of the data were obtained in the specific, optically complex environment of the Baltic Sea. Additional data, taken from the NASA bio-Optical Marine Algorithm Dataset (NOMAD) and representing various regions of the global oceans, were used to widen the potential applicability of the new formulas. We indicate the reasons why these simple empirical relationships can be derived and compare them with the results of straightforward modelling; possible applications are also described. We present, among other things, an example of a simple semi-analytical algorithm using both new empirical formulas. This algorithm is a modified version of the well-known quasi-analytical algorithm (QAA), and it can improve the results obtained in optically complex waters. This algorithm allows one to estimate the full spectra of the backscattering and absorption coefficients, without the need for any additional a priori assumptions regarding the spectral shape of absorption by dissolved and suspended seawater constituents.
Fault Feature Extraction and Diagnosis of Rolling Bearings Based on Enhanced Complementary Empirical Mode Decomposition with Adaptive Noise and Statistical Time-Domain Features
Authors: Zhan Liwei , Ma Fang , Zhang Jingjing , Li Chengwei , Li Zhenghui , Wang Tingjian
Published: September 2019

In this paper, a novel method is proposed to enhance the accuracy of fault diagnosis for rolling bearings. First, an enhanced complementary empirical mode decomposition with adaptive noise (ECEEMDAN) method is proposed by determining two critical parameters, namely the amplitude of added white noise (AAWN) and the ensemble trails (ET). By introducing the concept of decomposition level, the optimal AAWN can be determined by judging the mutation of mutual information (MI) between adjacent intrinsic mode functions (IMFs). Furthermore, the ET is fixed at two to reduce the computational cost. This method can avoid disturbance of the spurious mode in the signal decomposition and increase computational speed. Enhanced CEEMDAN demonstrates a more significant improvement than that of the traditional CEEMDAN. Vibration signals can be decomposed into a set of IMFs using enhanced CEEMDAN. Some IMFs, which are named intrinsic information modes (IIMs), effectively reflect the vibration characteristic. The evaluated comprehensive factor (CF), which combines the shape, crest and impulse factors, as well as the kurtosis, skewness, and latitude factor, is developed to identify the IIM. CF can retain the advantage of a single factor and make up corresponding drawbacks. Experiment results, especially for the extraction of bearing fault under variable speed, illustrate the superiority of the proposed method for the fault diagnosis of rolling bearings over other methods.
Privacy Aware Incentivization for Participatory Sensing
Authors: Connolly Martin , Dusparic Ivana , Iosifidis Georgios , Bouroche Mélanie
Published: September 2019

Participatory sensing is a process whereby mobile device users (or participants) collect environmental data on behalf of a service provider who can then build a service based upon these data. To attract submissions of such data, the service provider will often need to incentivize potential participants by offering a reward. However, for the privacy conscious, the attractiveness of such rewards may be offset by the fact that the receipt of a reward requires users to either divulge their real identity or provide a traceable pseudonym. An incentivization mechanism must therefore facilitate data submission and rewarding in a way that does not violate participant privacy. This paper presents Privacy-Aware Incentivization (PAI), a decentralized peer-to-peer exchange platform that enables the following: (i) Anonymous, unlinkable and protected data submission; (ii) Adaptive, tunable and incentive-compatible reward computation; (iii) Anonymous and untraceable reward allocation and spending. PAI makes rewards allocated to a participant untraceable and unlinkable and incorporates an adaptive and tunable incentivization mechanism which ensures that real-time rewards reflect current environmental conditions and the importance of the data being sought. The allocation of rewards to data submissions only if they are truthful (i.e., incentive compatibility) is also facilitated in a privacy-preserving manner. The approach is evaluated using proofs and experiments.
Polymer Fibers Covered by Soft Multilayered Films for Sensing Applications in Composite Materials
Authors: Nikoniuk Dorian , Bednarska Karolina , Sienkiewicz Maksymilian , Krzesiński Grzegorz , Olszyna Mateusz , Dähne Lars , Woliński Tomasz R. , Lesiak Piotr
Published: September 2019

This paper presents the possibility of applying a soft polymer coating by means of a layer-by-layer (LbL) technique to highly birefringent polymer optical fibers designed for laminating in composite materials. In contrast to optical fibers made of pure silica glass, polymer optical fibers are manufactured without a soft polymer coating. In typical sensor applications, the absence of a buffer coating is an advantage. However, highly birefringent polymer optical fibers laminated in a composite material are much more sensitive to temperature changes than polymer optical fibers in a free space as a result of the thermal expansion of the composite material. To prevent this, we have covered highly birefringent polymer optical fibers with a soft polymer coating of different thickness and measured the temperature sensitivity of each solution. The results obtained show that the undesired temperature sensitivity of the laminated optical fiber decreases as the thickness of the coating layer increases.
Perception to Adaptation of Climate Change in Nepal: An Empirical Analysis Using Multivariate Probit Model
Authors: GC  , Yeo
Published: September 2019

This study assessed farmers’ perception of climate change, estimated the determinants of, and evaluated the relationship among adaptation practices using the multivariate probit model. A survey in 300 agricultural households was carried out covering 10 sample districts considering five agro-ecological zones and a vulnerability index. Four adaptation choices (change in planting date, crop variety, crop type and investment in irrigation) were deemed as outcome variables and socioeconomic, demographic, institutional, farm-level and perceptions variables were deployed as explanatory variables. Their marginal effects were determined for three climatic variables—temperature, precipitation and drought. Age, gender and education of head of household, credit access, farm area, rain-fed farming and tenure, are found to be more influential compared to other factors. All four adaptation-options are found to be complimentary to each other. Importantly, the intensity of impact of dependent variables in different models, and for available adaptation-options, are found to be unequal. Therefore, policy options and support facilities should be devised according to climatic variables and adaptation options to achieve superior results.
Intra- and Inter-Annual Variability of Hydrometeorological Variables in the Jinsha River Basin, Southwest China
Authors: Peng Tian , Zhang Chu , Zhou Jianzhong
Published: September 2019

In this study, the intra- and inter-annual variability of three major elements in the water system, temperature, precipitation and streamflow, from 1974 to 2010 in the Jinsha River Basin, China, were analyzed. An exploratory data analysis method, namely, moving average over shifting horizon (MASH), was introduced and combined with the Mann–Kendall (MK) test and Sen’s slope estimation to analyze the intra- and inter-annual variations. The combination of MASH with the MK test and Sen’s slope estimation demonstrated that the annual temperature, precipitation and streamflow from 1974 to 2010 showed, on average, an increasing trend. The highest change in temperature was detected in early January, 0.8 ℃, that of precipitation was detected in late June, 0.4 mm/day, and that of streamflow was detected mid-August, 138 mm/day. Sensitivity analysis of the smoothing parameters on estimated trends demonstrated that Y parameters smaller than 2 and w parameters smaller than 6 were not suitable for trend detection when applying the MASH method. The correlation between the smoothed data was generally greater than that between the original hydrometeorological data, which demonstrated that the application of MASH could eliminate the influence of periodicity and random fluctuations on hydrometeorological time series and could facilitate regularity and the detection of trends.
PREVALENCE OF DEPRESSION AND ASSOCIATED FACTORS AMONG THE ELDERLY IN TRUONG QUANG TRONG WARD, QUANG NGAI CITY
Authors: Do Van Dieu , Doan Vuong Diem Khanh , Tran Nhu Minh Hang
Published: September 2019

Introduction: Depression is a common mental disorder in the elderly. It will be the leading cause of the global burden of disease by 2030.

Objectives:

(1) To identify the prevalence of depression among the elderly in Truong Quang Trong ward, Quang Ngai city using the GDS-30 scale.
(2) To analyze the factors associated with depression among participants.

Research methods: This was a descriptive cross – sectional study. A total sample of 447 people aged 60 and older living in Truong Quang Trong, Quang Ngai city were investigated. The GDS – 30 was used to identify depression and a semi – structure questionnaire was used to examine associated factors of depression. Multivariable logistic regression method was used to analyze factors associated with depression.

Results: The prevalence of depression in the participants was 15.9%, among which mild depression was 2.7%, average 9.2% and severe 4.0%. Associated factors with depression were physical activity, negative events in the past 12 months, stressful events in life, family structure-living conditions and genetic factors.

Conclusion: In this population, prevalence of depression in the elderly was quite high, therefore early detection and identification of risk factors of depression are essential for early intervention and prevention of this disorder.

Key words: Depression, elderly, Truong Quang Trong Ward, Quang Ngai City
IMAGING ON 64 MDCT OF THE UPPER URINARY TRACT OF RENAL LIVING-RELATED DONORS
Authors: Duong Phuoc Hung , Le Trong Khoan , Nguyen Khoa Hung
Published: September 2019

Objectives: Evaluating the morphology of the upper urinary tract of renal living-related donors with 64 Multi - Detectors Computed Tomography (MDCT).

Subjects and methods: From 01/2017 to 10/2018, when carrying out a prospective study at Cardiovascular Centre of Hue Central hospital, we have performed 64 MDCT of the upper urinary tract (MDCT-UUT) on 312 renal living-related donors among which, there are 265 males and 47 females aged from 20 to 60.

Results: 100% of donors experience no contrast-induced artifacts in renal parenchyme. 71.47% of visualization of contrast media (CM) of entire upper urinary tract filling and 100% of visualization of CM of top half upper urinary tract filling in both of kidney. The majority of donors have single collecting system (99.04% in right kidney and 99.68% in left kidney). The rest has partial or complete duplex collecting system. 64 MDCT has high value in detecting stone of the upper urinary tract (8.01%) in comparison with KUB Radiograph (0%) and abdominal Ultrasonography (0.32%). 100% of donors have normal renal function in the excretory phase at 5 minute after CM and NaCL 0.9% injection bolus. This allows reducing examination time and radiation exposure with the highest effective dose 5.88mSv in unenhanced and excretory phases.

Conclusions: 64 MDCT-UUT contributes into more accurate diagnosis of the morphology of the upper urinary tract of renal living-related donors, helps surgeons make appropriate planning in the operation of chosen kidneys of living-related donors and transplanting into patients.

Key words: Upper urinary tract - 64 MDCT - MDCT-UUT
ASSESSMENT ON RESULTS OF SURGICAL EXTRACTION OF&NBSP; IMPACTED LOWER THIRD MOLARS WITH POSTOPERATIVE LOW - LEVEL LASER THERAPY
Authors: Nguyen Thi Mai Huong , Tran Tan Tai , Hong Quoc Khanh
Published: September 2019

Background: The most frequently performed surgical procedure in dentistry is impacted third molar extraction with difficulty varies according to the location of the tooth. Laser therapy after surgery can accelerate cell and tissue reconstruction along with relieve post-operative pain. The objective of this study was to investigate the clinical and radiographic characteristics of impacted lower third molar and to evaluate the results of surgical extraction of impacted lower third molar with post-surgical low-level laser therapy (LLLT).

Subjects and Methods: Clinical and radiographic data from 90 patients (average age 28.13 ± 5.38) subjected to a surgical extraction of lower third molar were pooled and divided randomly into 3 groups: group 1 received LLLT immediately after surgery intraorally, group 2 treated with LLLT immediately after the extraction extraorally. Patients received routine management with nonactivated laser were inserted in the control group. Assessments of pain, swelling and trismus level were carried out at 24, 48 hours and on the 7th day after surgery.

Results: Correlation of wisdom teeth to ramus and adjacent teeth mainly type II (88.9%), type III accounted for 11.1%. Relative depth of wisdom teeth in the bone mainly position B (81.1%), position C (18.9%). Correlation of wisdom teeth axis to adjacent teeth: horizontal (58.9%), mesioangular impactions (40%) and distoangular impaction (1.1%). There were statistically significant decreases in the level of pain, edema and interincisal opening between the laser-treated groups and the control group on the 1st and 2nd postoperative day.

Conclusions: Intraoral and extraoral post-surgical low-level laser therapy treatment was useful in reducing swelling, pain and trismus compared to placebo group in impacted third molar surgery.

Key words: Impacted lower third molar, low- level laser therapy
RETROPERITONEALS SINGLE INCISION LAPAROSCOPIC NEPHRECTOMY: MINI-INVASIVE TECHNICAL, SAFETY AND COSMETIC
Authors: Ngo Thanh Liem , Nguyen Khoa Hung , Hoang Van Tung
Published: September 2019

Objective: Outcome of 45 retroperitoneal single incision laparoscopic nephrectomy of benigns nonfunction kidneys at Hue Central Hospital. Patients and method: A prospective study was perform on 45 patients with benign nonfuncion kidney, treated by retroperitoneal single incision laparoscopic nephrectomy at Department of General Surgery - Hue Central Hospital from May 2015 to August 2018. Results: Success: 42/45 patients. Mean operating time 87.5mins (50 - 155 mins), postoperative hospital stay 5-7 days. SILS Port of Covidien was inserted by 2.5 cm skin transverse incision, standard straight laparoscopic instruments were used instead of roticular instruments. Conclusion: This is a mini-invasive technical, safety and cosmetic
Keywords: retroperitoneal single incision laparoscopic nephrectomy, single port nephrectomy.
A STUDY OF COMMON COMPLICATIONS IN ACUTE LEUKEMIA PATIENTS AT PEDIATRIC CENTER IN HUE CENTRAL HOSPITAL
Authors: Nguyen Van Tuy , Phan Hung Viet
Published: September 2019

Background: Acute leukemia is the most common malignant disease in children. Patient typically die for complications, there occur as a consequence of treatment and the disease itself.

Objectives: To describe the rate and the clinical, paraclinical features of common complications in acute leukemia patients before and during induction therapy.

Subjects & methods: A survey was conducted with 34 acute leukemia patients at The Pediatric Center in Hue Central Hospital from 4/2017 to 7/2018.

Results: Infection were the most common complication as a percentage of 91.2%, the propotion of severe anemia and severe hemorrhage were at 85.3% and 35.3%.

Conclusions: The percentage of infection, severe anemia and severe hemorrhage decreased in period of the last 2 weeks of induction therapy, in which the proportion of severe anemia declined significantly in statistics. Neutrophil counts, platelet counts and hemoglobin levels were significantly increased when patients entered to the last 2 weeks of induction therapy.

Key words: complication, acute leukemia, induction therapy
Connections between land usage, property structure and agricultural enterprises in Hungary
Authors: Nagyné Demeter Dóra
Published: September 2019

The last decade of Hungarian agriculture was marked and changes which affected all parts of agricultural production. This process resulted in a new ownership and organisation structure. The paper presents the effects of the changes in ownership on land use and the various enterprise forms and intends to outline the main tendencies. In general, it can be stated that the role of agriculture in GDP production and employment is decreasing in Hungary, but according to concurrent opinions of experts, agriculture still has and will have a major role in income production and the ease of social tensions in rural areas in the future as well. Hungary’s accession to the European Union provides new chances and new prospects for Hungarian agriculture and rural areas. Hungarian agriculture became a part of the internal market which includes about 450 million people. The safety of marketing became stronger, the rate of financial support is increasing and the income of growers will increase in the future. This process implies more obligations and the keeping of strict regulations. Competition inside the internal market is intensifying, competitiveness will be more important while the chances of development and investment of the growers and the feasibility of more effective land use are increasing. After the accession, integration into the directives formulated in the CAP and the packages of measures accepted in it is framework have growing importance.These directives encourage farm-reallocation, namely the rational estate concentration. In general, it can be stated that rational estate concentration, and more effective land use as a consequence, will increase the efficiency of agricultural production.
The use of biogas in energetics
Authors: Sallai László , Molnár Tamás , Fodor Dezső
Published: September 2019

In our study we examine the technical facilities of biogas production in the economic environment of a given region. The region can be considered as typical: it has animal farms, a poultry-processing plant with the characteristic problems of environment load and by-product handling. Biogas can be used for energetic purposes, and, in large scale, it can be sold as electric energy. The heat coming from the engine and the generator can be collected in heat exchangers and can be used for preparing hot water and for heating. One third of the gained energy is electric, two thirds are heat. The aim of the local owner and the economic management is to increase the rate of cost-effectiveness in general. We examined the tecnnical and economic conditions of establishing a biogas plant (using data of an existing pigfarm). We planned the biogas plant and calculated the expected investment and operational costs and return.
The analysis of the fair data of a solar energy power plant with SPSS
Authors: Szecskó Zoltán
Published: September 2019

The use of fossil energy sources greatly damages the environment. Moreover, the quantity of these energy sources is limited. Therefore, it is important to increase the share of renewable energy sources (solar, wind, water and biomass) in energy generation.Huge amounts of energy (1100-1300 kWh/m2 per year) arrive at the earth from the sun, and are utilized in passive and active ways. One of the active applications is photovoltaic current production, in the course of which electricity is produced directly with PV – panels. This can be fed into a grid. At the University of Debrecen is a solar energy power plant from September 2005 in operation. The electricity performance of the incorporated PV-panels (Kyocera, Dunasolar, and Siemens) are 8.64 kW. The are of PV – panels is 110 square meter. With the aid of the data storage, the tension, current, temperature of the PV-panels, global radiation, air temperature, wind speed, wind direction and the achievement is measured by the ac network.The effect of the shading on the performance of the PV – panels and the solar energy power plant is examined. The analysis and the graphic representation of the experiment results are carried out with SPSS per grief. We produced per grief.
Possibilities of selection and production of blue and ornamental corn (Zea mays L.)
Authors: Bódi Zoltán , Pepó Pál
Published: September 2019

The cultivation of alternative crops has an important role in world agriculture. Their market share is continuously growing in the food industry sector. In the present study, we show the cultivation and breeding perspectives of ornamental and blue corn. There exists possibility to cultivate ornamental corn in Hungary. There are many cultivars of ornamental corn, with various kernel colors, husks, stalks and leave colors. Blue corn is unique among other corns. Blue corn higher in protein, iron and zinc than commercial dent corn. Pests affective ornamental and blue corn are the same as those of other commercial corns. Ornamental and blue corns need to be grown a minimum of 500 m away from commercial yellow dent corn to minimize any cross pollination which may result in off-color kernel. Our aim in the presentation of this review was to broaden Hungarian literature.
Selenium-speciation experiments from soil samples by accept of ionchromatography-inductively coupled plasma mass spectrometry (IC-ICP-MS) method
Authors: Széles Éva , Kovács Béla , Prokisch József , Győri Zoltán
Published: September 2019

In these days, selenium is one of the most investigated microelements. It has an important proven role in many vital processes. Selenium deficiency can play a role in the contraction of many diseases (e.g. cancer, heart diseases, etc.) and in the aggravation of their clinical aspect directly or indirectly. In this paper, we study the soil samples of an outdoor experiment for the conversion of the inorganic selenium salt that was spread out in different doses. The danger of the wash-out effect was also investigated. Our experiments showed, that most of the inorganic selenite transforms to selenate form during the years, and in this selenate form it moves to the deeper layers of soil.
Perancangan Media Komunikasi dan Informasi Sekolah PPPK Petra Surabaya Dalam Bentuk Aplikasi Smartphone Berbasis Android
Authors: Susilo Christyan Budi , Noviadji Benny Rahmawan , Wigeno Robi
Published: September 2019

Sekolah PPPK Petra merupakan salah satu lembaga pendidikan di Surabaya. Media informasi dan komunikasi cetak yang dibagikan kepada siswa, orang tua, serta guru dan karyawan selama ini sangat jarang dibaca, bahkan yang diedarkan kepada siswa di jenjang SMP dan SMA banyak ditemukan di tempat sampah dan juga dibuat sebagai mainan pesawat kertas. Hal tersebut menjadi tidak efisien, karena dana yang dikeluarkan untuk pencetakan tidak sedikit. Metode yang dipakai dalam penelitian ini yaitu prototyping. Cara pengumpulan data yang digunakan adalah melalui wawancara mendalam, kuesioner, observasi dan survei. Selain itu juga dilakukan studi komparator dan kompetitor terhadap aplikasi sejenis. Sedangkan dalam membantu analisis dan perancangan desain User Interface menggunakan kuesioner kriteria desain. Hasil dari penelitian pada Sekolah PPPK Petra dilakukan perancangan media komunikasi dan informasi dalam bentuk aplikasi smartphone berbasis Android. Penggunaan aplikasi mobile pada Android diharapkan mampu menjadi media komunikasi bagi sekolah dan dapat menyampaikan informasi secara cepat dan mudah kepada siswa dan orangtua. Selain pembuatan aplikasi, tentunya diperlukan media untuk mempromosikan aplikasi ini agar orang-orang dapat mengetahui keberadaan aplikasi ini. Media pendukung yang digunakan untuk melakukan promosi meliputi poster, spanduk, x-banner dan web banner pada website PPPK Petra.
WEB-BASED LOGISTIC DEMAND INFORMATION SYSTEM DESIGN AT RAHARJA UNIVERSITY
Authors: Khasanah Dewi Nur , Wulandari Siti , Dwi Rosmawati
Published: September 2019

In the present Information Technology (IT) is highly developed. Even in daily life, everything is computerized, such as in companies, schools, offices, shopping centers, and many more. Nearly the average has used a computerized system for service and information presentation. With this computerized system, it is expected to be able to facilitate in all aspects of life. The purpose of this study is to design a logistics goods demand system at Raharja College. The approach taken in this report is by direct observation through field studies. To examine how the procedure for processing logistical demand data at Raharja University. Data processing is very important to produce a logistical demand report. The logistical demand data processing system that runs currently is semi computerized using Microsoft office Excel. So that errors often occur in the calculation of logistics goods demand reports and the processing process becomes less effective in terms of time. This study uses a SWOT analysis method, system requirements elicitation, and system modeling using UML (Unified Modeling Language) to visualize, which is then implemented with the Hypertext Preprocessor (PHP) programming language with the MySQL-Server database as the database used. With the logistics demand system, it can make it easier for the finance department to produce accurate logistics goods demand reports with fast time, so that it can create effective and efficient performance, and can support evaluation in internal control for the leadership of the report.
Emprendimiento desde la práctica del reciclaje ecológico
Authors: Loor Moreira Alexandra Jacqueline , Molina Quiroz Claudia Analia , Baduy Molina Aarón Leonel
Published: September 2019

La investigación tuvo por objetivo analizar el emprendimiento desde la práctica del reciclaje ecológico en las instituciones educativas de Manta, Ecuador. Metodológicamente se fundamentó en una tipología descriptiva. Desde una educación creativa e innovadora, pueden desarrollarse en los estudiantes para configurarse como emprendedores, de ese modo, la escuela se constituye en un factor primordial para el crecimiento humano, se puede generar la innovación y creatividad al impulsar proyectos para el desarrollo de ideas de emprendimiento ecológico que además permitan formar en valores, entre estas actividades se encontrarían: servicio de reciclaje a domicilio, asesoramiento ecológico para instituciones públicas y privadas, diseño y acondicionamiento de áreas verdes, diseño de app con visión ecológica, podrían ser algunos de los emprendimientos a generar.
Prevención de lavado de activos. Un enfoque desde la gerencia
Authors: Quevedo Barros Manuel Rafael , Quevedo Vázquez Jorge Oswaldo , Villareal Cherrez Tania Maricela , Guamán Herrera Patricia Guadalupe
Published: September 2019

Recibido: 23 de abril del 2019Aprobado: 25 de mayo del 2019La prevención del lavado de activos, está en correspondencia con la estricta identificación del cliente y por las políticas y procedimientos de verificación de sus activos. Sin embargo, es muy común el crecimiento de este delito. En atención a esta proposición, se realizó este artículo cuyo objetivo fue caracterizar la prevención del lavado de activos desde un enfoque gerencial. La metodologia fue de tipo Documental, y en cuanto al nivel de conocimiento, se puede señalar como descriptiva, cuando busco encontrar las características, comportamiento y propiedades desde el corpus documental que refirieron las teorías del lavado de activos. Entre sus resultados se pudo constatar  que la  mayoría de los  lavado de activos, logran su  estabilidad  en atención a la variación del  tiempo.
DYNAMICS OF
WHITE BLOOD CELL COUNT INDEXES AS REFLECTION OF THE CHANGING
CONDITION OF ADAPTATION DURING GROWTH OF HEALTHY CHILDREN
THE FIRST YEAR OF LIFE
Authors: Chernova G.V. , Dykova E.V. , Sidorov V.V. , Timofeeva M.A. , Shiryaeva L.V.
Published: September 2019

There were conducted biometric studies and quantitative assessment of variability of indexes of white
blood cell count of healthy children of the first year of life (data of the biometric analysis are presented in
graphic form). It was revealed that the total number of white blood cells in 78,7 % cases was determined
genetically, defining differences in variability of indexes at boys and girls. At the same time cells of a
granulocytes row expressed such feature only in 12,2 % of cases.
Change in the content of granulocyte row cells in the peripheral blood of children of the first year of life
in the conditions of the non-ionizing radiation of natural origin demonstrates the formation of a
response of adaptation system components.
The data on dynamics of the relations of granulocytes and lymphocytes (indexes) obtained by authors
have a theoretical and applied significance for development of criteria for evaluation the functional
condition of adaptation system and health of children.
ANALYSIS OF THE
EFFECTIVENESS OF THE IMPLEMENTATION OF THE PILOT PROJECT OF
VACCINATION AGAINST PNEUMOCOCCAL INFECTION IN RISK GROUPS IN
THE MUNICIPALITIES LEADING ON INDICATORS OF MORTALITY FROM
COMMUNITY-ACQUIRED PNEUMONIA
Authors: Kozlova I.I. , Sisin E.I. , Ostapenko N.A. , Ezhova O.A. , Kashapov N.G.
Published: September 2019

There were established municipalities with the highest mortality rates from community-acquired
pneumonia (CAP). When etiological deciphering of CAP confirmed the role of S. pneumoniae (Klein)
Chester in the development and outcome of this disease. Among the risk contingents were vaccinated
against pneumococcal disease, which had an impact on morbidity and mortality from CAP. It is proved
that the vaccination of contingent risk against pneumococcal disease reduces the morbidity and
mortality from CAP.
MONITORING OF NATURAL FOCAL INFECTIONS ON THE SOUTHERN EUROPEAN PART OF RUSSIA IN 2016
Authors: Vasilenko N.F. , Maletskaya O.V. , Manin E.A. , Prislegina D.A. , Shaposhnikova L.I. , Volynkina A.S. , Lisitskaya Ya.V. , Varfolomeyeva N.G. , A.N. Kulichenko
Published: September 2019

The results of epizootological monitoring of the Southern European part of Russia (Southern and North- Caucasian Federal Districts), which has been tested for 18 nosological forms of natural focal infections are presented. There have been tested the laboratory studies of 45 615 samples of field material, the markers of pathogens of 15 nosological forms are identified. The circulation of Crimean-Congo hemorrhagic fever virus is identified in 10 subjects, the pathogen of tularemia – in eight regions, Lyme borreliosis – in seven, Q fever – in six; pathogens of hemorrhagic fever with renal syndrome, West Nile fever, leptospirosis and human granulocytic anaplasmosis – in five subjects. The markers of pathogens of human monocytic ehrlichiosis and tick-borne viral encephalitis were detected in four subjects, pseudotuberculosis and intestinal yersiniosis – in three and Arboviruses (Sindbis, Inkoо, Tahyna) – in one region.
PREVALENCE OF ICE ELEMENTS OF DIFFERENT TYPES IN V. CHOLERAE
Authors: Vodop'yanov S.O. , Vodop'yanov A.S. , Oleynikov I.P. , Titova S.V.
Published: September 2019

With the help of a virtual PCR in silico analysis of the local database 395 genome-nucleotide sequences of Vibrio cholerae in the presence of ICE element. The results showed widespread ICE member from toxigenic strains and nontoxigenic Vibrio cholerae O1 serotype. Thus all elements of ICE successfully typed three basic types – «Indian», «Mozambique», or «the SXT». In this case up to 40 % nontoxigenic strains O1 serovar and nonO1/nonO139 carried ICE element. When analyzed by PCR in vitro collection of 222 strains of Vibrio cholerae O1 serotype shows the presence of ICE element and determine its type in toxigenic strains isolated in recent years in the Russian Federation. All nontoxigenic O1, O139 and nonO1/nonO139 strains isolated in Russia, deprived of ICE element that differs from strains circulating in endemic cholera areas. This observation allows us to consider the presence of ICE element as a new epidemic marker «of invasive strains of» nontoxigenic Vibrio cholerae.
ECYINOCCOSES IN THE URAL FEDERAL OKRUG OF
RUSSIA. REPORT 2: EPIZOOTICAL ACPECTS OF THE ISSUE
Authors: Peklo G.N. , Stepanova T.F.
Published: September 2019

Using the results of a long-term research in infestation of wild and domestic animals with E. granulosus
and E. multilocularis, as well as data provided by the regional veterinary service management and the
Federal Centre of Gossanepidnadzor (State Sanitary and Epidemiological Supervision Agency), we point
at the urgency of the echinoccosis problem in the animals of the Ural Federal Okrug. The problem that
has become medico-veterinary and social in our country demands not only to systematically survey the
biocenotic composition of natural, combined and synanthropic foci in the territory of the Federal Okrug,
but also does it dictate the necessity to conduct constant sanitary and anti-epidemic measures in
synanthropic foci.
PARTICIPATION OF BACTERIOLOGICAL AND PARASITOLOGICAL
LABORATORIES IN INTERLABORATORY COMPARATIVE TESTS
Authors: Aslanova M.M. , Zarochentsev M.V. , Kuznetsova K.Yu. , Yaroslavtseva M.A. , Shikhbabaeva F.M. , Rudinsky A.V.
Published: September 2019

A retrospective analysis of the participation of microbiological and parasitological laboratories in
interlaboratory comparative trials is presented, and the importance of carrying out these tests in
laboratory centers to confirm their competence is reflected.
EVALUATION OF PHYSICAL DEVELOPMENT OF SCHOOL-AGE BOYS IN SAINT PETERSBURG WITH THE USE OF THE ANTHROPOMETRIC CALCULATOR OF WHO
Authors: Gritsinskaya V. L.
Published: September 2019

The indicators of the physical development of 3225 schoolboys from St. Petersburg from 7 to 17 years old were studied. Assessment of the level and harmony of physical development was carried out in accordance with the WHO standards («WHO Growth Reference 2007») using the program «WHO AnthroPlus». The asymmetry of body length indices with a significant representation of tall school children (1.9– 10.9 %) is established. The high level of disharmonious variants of physical development, caused by overweight and obesity (16.4-38.2%) was revealed in the schoolchildren surveyed. The necessity of developing a complex of preventive programs aimed at the formation of a healthy lifestyle, balanced nutrition and increasing the motor activity of the younger generation is substantiated.