bluuebunny/crossref_metadata_2025 huggingface dataset:
RETHINKING (DIS)FLUENCY WITHIN THE SCOPE OF INTERACTIONAL LINGUISTICS AND GESTURE STUDIES
Authors: KOSMALA Loulou
Published: August 2022

The study of so-called ‘disfluency’ phenomena (uh and um, filled and unfilled pauses, self-repairs and the like) has gained a lot of attention in various fields in linguistics in the past few decades, but a majority of studies tend to be production-oriented and often disregard fundamental aspects of face-to-face communication such as interactional dynamics and gesture. This paper presents a multimodal and multilevel model of “inter-fluency”, considering different levels of analysis, mainly, talk, gesture, and interaction, by combining different theoretical frameworks and methodologies in gesture studies and interactional linguistics in order to bridge this gap and go beyond previous cognitive-oriented models.
LES DROITS HUMAINS AU PRISME DES PARTICULARISMES CULTURELS : QUELLE ALTERNATIVE ?
Authors: BAMAZE N’GANI Essodina
Published: August 2022

Human Rights through the Lens of Cultural Particularities: What Alternative? While the proclaimed universality of human rights is a guarantee of security and protection for every human being, its implementation faces several cultural roadblocks. This paper clearly posits that the transcendent aspect of universality creates legal foreignness. We postulate that this foreignness is the source of particularistic hatred against the universality of human rights. In the light of this hypothesis, which is illustrated by excisions, this study recommends a translation of the universal language of human rights into local cultural contexts. Such a translation constitutes an effective antidote to any particularistic approach, because we believe that it creates space for shared responsibility towards universality. In this regard, this paper intends to rethink the very foundation of the universality of human rights as rooted in order to eventually demonstrates the relevance of its translation into local cultural contexts. The transcendent vision of human rights (and law in general) is therefore complemented by their taking root perception by the societies they seek to govern. Otherwise, these rights will always be perceived as extraneous values at the endogenous level of cultures. Hence their ineffectiveness.
SHOULD WE SUSPEND THE TRUTH TO PREVENT HARM?
Authors: OLANIPEKUN Olusola Victor
Published: August 2022

The paper examines the ethics of truth telling and free speech in Jonathan Rauch’s "The Humanitarian Threat". The central question is this: “Should we suspend the truth to prevent harm?”. Both humanitarians and the anti-humanitarians supply different responses to this question. While the humanitarians supplied a positive answer, Rauch argues that the anti-humanitarian posture of the exponents of liberalism supplied a negative answer. The paper considers the humanitarian argument that puts the welfare of the people above the truth or anything else. Meanwhile, for the anti-humanitarians, the right to speak the truth must be guaranteed at all time. This paper argues that, in practice, the morality of truth telling is not only context bound, it also depends on what the truth is meant to achieve. Thus, the suspension of the truth may be consistent with morality in some medical and sensitive security situations due to the tendency to cause harm. The paper does not argue that the truth be suspended arbitrarily or for mischievous reasons. It only concludes by identifying some practical situations under which suspension of the truth may not be inconsistent with morality.
„Mér líður eins og ég tilheyri, veit að hún lærir tungumálið fljótt.“ Foreldrar með fjölbreyttan bakgrunn og fullgildi við upphaf leikskólagöngu
Authors: Pálmadóttir Hrönn
Published: August 2022

Greinin er byggð á rannsókn þar sem leitast var við að skilja hvaða merkingu foreldrar með fjölbreyttan bakgrunn leggja í reynslu sína af samskiptum og þátttöku við upphaf leikskólagöngu barna sinna. Í rannsókninni er stuðst við hugtakið fullgildi sem er þýðing á enska hugtakinu belonging. Það vísar til tilfinningar einstaklingsins af félagslegum tengslum ásamt tækifærum til samskipta og þátttöku. Hugtakið fullgildi er margslungið og greinir Yuval-Davis (2006, 2011) á milli tilfinningalegs fullgildis (e. sense of belonging) og pólitísks fullgildis (e. politics of belonging). Fullgildi er talið tengjast grundvallarþörf manneskjunnar um að tilheyra fólki, stöðum eða hlutum. Reynsla fólks af því að tilheyra hafi þannig áhrif á nám, hegðun, vellíðan og sjálfsmynd þess (May, 2013; Stratigos o.fl., 2014). Eigindlegar rannsóknaraðferðir voru notaðar við öflun gagna. Tekin voru hálfopin viðtöl við átta foreldra sex barna; feður og mæður tveggja barna og mæður fjögurra barna. Börnin voru öll undir tveggja ára aldri og höfðu verið í leikskólanum frá tveimur upp í fimm mánuði þegar rannsóknin hófst. Foreldrar tveggja barna voru með erlendan bakgrunn, tvö barnanna með íslenskan bakgrunn og tvö þeirra með annað foreldri með erlendan bakgrunn. Tvö barnanna nutu sérstaks stuðnings í leikskólanum. Greining gagna fór fram með þemagreiningu, en hún er sveigjanleg aðferð sem notuð er til að skipuleggja og greina gögn (Braun og Clarke, 2013). Niðurstöður rannsóknarinnar sýndu að upphaf leikskólagöngu fól í sér miklar breytingar á lífi fjölskyldnanna. Val á leikskóla, þáttökuaðlögun og skipulag leikskólastarfsins sköpuðu mikilvægan grunn fyrir væntingar foreldranna af samskiptum og þátttöku í samfélagi leikskólans í framhaldinu. Í hugum foreldra var fullgildi samofið tilfinningunni af trausti og öryggi í garð leikskólans. Mikilvægt væri að leikskólinn stuðlaði að tengslum og samstarfi við foreldra, auk þess að leggja áherslu á tungumál og félagsleg samskipti barnanna í því augnamiði að þau upplifðu fullgildi innan barnahópsins.
Prognostic value of right ventricle to pulmonary artery coupling in transcatheter aortic valve implantation recipients
Authors: Adamo Marianna , Maccagni Gloria , Fiorina Claudia , Giannini Cristina , Angelillis Marco , Costa Giulia , Trani Carlo , Burzotta Francesco , Bruschi Giuseppe , Merlanti Bruno , Poli Arnaldo , Ferrara Erica , Fineschi Massimo , Iadanza Alessandro , Chizzola Giuliano , Metra Marco
Published: August 2022

Aims

To investigate the impact of the right ventricle to pulmonary artery (RV-PA) coupling on the outcome of patients undergoing transcatheter aortic valve intervention (TAVI), and to describe changes in right ventricular function, pulmonary hypertension, and their ratio after TAVI.

Methods

Three hundred and seventy-seven patients from the Italian ClinicalService Project, who underwent TAVI between February 2011 and August 2020, were included. Tricuspid annular plane systolic excursion/pulmonary artery systolic pressure (TAPSE/PASP) ratio was retrospectively calculated as a surrogate of RV-PA coupling. The population was stratified according to TAPSE/PASP using a cut-off of 0.36 mm/mmHg derived from a receiving operating characteristic (ROC) curve. The primary end point was 6-month all-cause death.

Results

Compared with patients with a TAPSE/PASP ratio ≥0.36 mm/mmHg (81%), those with TAPSE/PASP ratio <0.36 mm/mmHg (19%) had more comorbidities and were more symptomatic.

Moreover, they were more likely to receive general anesthesia and an old generation device. Device success was similar between the two groups. A TAPSE/PASP ratio <0.36 mm/mmHg was associated with a higher risk of all-cause death at 6-months (17.3% versus 5.3%; adjusted HR 2.66; P = 0.041). The prognostic impact of the TAPSE/PASP ratio was stronger than the impact of TAPSE and PASP as separate parameters and was independent of the surgical risk score. Both TAPSE, PASP, and their ratio improved from baseline to 1 month and 6 months after TAVI.

Conclusions

A TAPSE/PASP ratio <0.36 mm/mmHg is strongly associated with an increased risk of mortality after TAVI. Providing a left ventricle unloading, TAVI is associated with improvement of both TAPSE, PASP, and their ratio.
Role of computed tomography in transcatheter replacement of ‘other valves’: a comprehensive review of preprocedural imaging
Authors: Pugliese Luca , Ricci Francesca , Luciano Alessandra , De Stasio Vincenzo , Presicce Matteo , Spiritigliozzi Luigi , Di Tosto Federica , Di Donna Carlo , D’Errico Francesca , Benelli Leonardo , Pasqualetto Monia , Grimaldi Francesco , Mecchia Daniele , Sbordone Paolo , Cesareni Matteo , Cerimele Cecilia , Cerocchi Martina , Laudazi Mario , Leomanni Paola , Rellini Carlotta , Dell’Olio Vito , Patanè Alberto , Romeo Francesco , Barillà Francesco , Garaci Francesco , Floris Roberto , Chiocchi Marcello
Published: August 2022

Transcatheter procedures for heart valve repair or replacement represent a valid alternative for treating patients who are inoperable or at a high risk for open-heart surgery. The transcatheter approach has become predominant over surgical intervention for aortic valve disease, but it is also increasingly utilized for diseases of the ‘other valves’, that is the mitral and, to a lesser extent, tricuspid and pulmonary valve. Preprocedural imaging is essential for planning the transcatheter intervention and computed tomography has become the main imaging modality by providing information that can guide the type of treatment and choice of device as well as predict outcome and prevent complications. In particular, preprocedural computed tomography is useful for providing anatomic details and simulating the effects of device implantation using 3D models. Transcatheter mitral valve replacement is indicated for the treatment of mitral regurgitation, either primary or secondary, and computed tomography is crucial for the success of the procedure. It allows evaluating the mitral valve apparatus, the surrounding structures and the left heart chambers, identifying the best access route and the landing zone and myocardial shelf, and predicting obstruction of the left ventricular outflow tract, which is the most frequent postprocedural complication. Tricuspid valve regurgitation with or without stenosis and pulmonary valve stenosis and regurgitation can also be treated using a transcatheter approach. Computer tomography provides information on the tricuspid and pulmonary valve apparatus, the structures that are spatially related to it and may be affected by the procedure, the right heart chambers and the right ventricular outflow tract.
The Psychological Memory Forgetting Model Based on the Analysis of Linear Differential Equations
Authors: Yang Yangang
Published: August 2022

The article uses mathematical theory to derive a quasi-linear differential equation describing the law of memory forgetting in psychology. The nonlinear automatic control machine model is used to preliminary model the indiscriminate memory problem in psychology. The research obtains the recommended evaluation value with the forgetting characteristics in memory psychology. The experimental results found that the model reasonably solves the problem of quantification of timeliness.
Effective Outcome of HBOT as an Adjuvant Therapy in Patients Diagnosed with COVID-19 in a Tertiary Care Hospital – A Preliminary Study
Authors: Palaniappan Thiruppathy , Shaikh Asif , Kirthika Navamani
Published: August 2022

Introduction

Hyperbaricoxygen therapy (HBOT) is breathing100% oxygen in pressurised chamber. This therapy ensures quick oxygen delivery to the bloodstream. In patients with severe COVID-19 pneumonia, progressive hypoxemia occurs. Oxygen therapy hasa significant role in its management.

Aim of the study

The objective was to study the efficacy of hyperbaric oxygen therapy (HBOT) as adjuvant therapy for reducing the requirement of additional oxygen supplementationin patients with moderate to severe ARDS diagnosed with COVID-19.

Methods

A single-centre prospective pilot cohort study was conducted ata tertiary care hospital from December 2020 to February 2021 over two months. Fifty patients with COVID-19 needingoxygen, satisfying the selection criteria, were included. Hyperbaricoxygen therapy wasgiven to all patients. The patient received30-45 minutes of hyperbaric oxygen with 15 minutes of pressurizing and depressurizing at 2.0 atmosphere absolute (ATA) with or without airbrakesas per the critical care team. Oxygen requirement, PaO2, andcondition at discharge were considered as primary outcome variables.

Results

Among the 50 participants studied, the mean age was 53.64±13.26 years. Out of 50 participants, 49(98.00%) had PaO2≤80 mmHg, and one (2.00%) had >80 PaO2. All the participants 50(100%) had PaO2 as 90 mmHg after three sittings.

Conclusion

This studyshows promising results in using HBOT to overcome respiratory failure in COVID-19. HBOT reduced the need for oxygen by improving the oxygen saturation levels.
Predictive Value of Systemic Immune-inflammation Index in Determining Mortality in COVID-19 Patients
Authors: Karaaslan Tahsin , Karaaslan Esra
Published: August 2022

Aim

The aim of this study was to evaluate whether systemic immune-inflammation index (SII) could predict mortality in patients with novel coronavirus 2019 (COVID-19) disease.

Methods

This two-center, retrospective study included a total of 191 patients with confirmed diagnosis of COVID-19 via nucleic acid test (NAT). The SII was calculated based on the complete blood parameters (neutrophil × platelet/lymphocyte) during hospitalization. The relationship between the SII and other inflammatory markers and mortality was investigated.

Results

The mortality rate was 18.3%. The mean age was 54.32±17.95 years. The most common symptoms were fever (70.7%) and dry cough (61.3%), while 8 patients (4.2%) were asymptomatic. The most common comorbidities were hypertension (37.7%), diabetes (23.0%), chronic renal failure (14.7%), and heart failure (7.9%) which all significantly increased the mortality rate (p<0.001). There was a highly positive correlation between the SII and polymorphonuclear leukocyte (PNL), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) (r=0.754, p<0.001; r=0.812, p<0.001; r=0.841, p<0.001, respectively), while a moderate, positive correlation was found between the SII and C-reactive protein (CRP) (r=0.439, p<0.001). There was a significant correlation between the SII and mortality (U=1,357, p<0.001). The cut-off value of SII was 618.8 (area under the curve=0.751, p<0.001) with 80.0% sensitivity and 61.5% specificity. A cut-off value of >618.8 was associated with a 4.68-fold higher mortality.

Conclusion

Similar to NLR and PLR, the SII is a proinflammatory marker of systemic inflammation and can be effectively used in independent predicting COVID-19 mortality.
Right Heart Failure as an Atypical Presentation of Chronic Type A Aortic Dissection - Multimodality Imaging for Accurate Diagnosis and Treatment. A case report and mini-review of literature
Authors: Tilea Ioan , Dumbrava Robert Adrian , Ratiu Alexandra Mihaela , Harpa Marius Mihai , Banceu Cosmin Marian , Petra Dorina Nastasia , Suciu Horatiu
Published: August 2022

Background

An intrapericardial organized haematoma secondary to chronic type A aortic dissection is an extremely rare cause of right heart failure. Imaging studies are essential in recognising and diagnosis of this distinctive medical condition and guiding the anticipated treatment.

Case presentation

A 70-year-old male patient was admitted for progressive symptoms of right heart failure. His cardiovascular history exposed an aortic valve replacement 22 years before with a Medtronic Hall 23 tilting valve with no regular follow-up. Classical signs of congestion were recognized at physical examination. Transthoracic two-dimensional echocardiography and thoraco-abdominal computed tomography angiography, as essential parts of multimodality imaging algorithm, established the underlying cause of right heart failure. Under total cardiopulmonary bypass and cardiac arrest, surgical removal of the haematoma and proximal repair of the ascending aorta with a patient-matched vascular graft were successfully performed. The patient was discharged in good condition with appropriate pharmacological treatment, guideline-directed; no imagistic signs of acute post-surgery complications were ascertained.

Conclusion

This paper highlights the importance of recognizing and providing a timely clinical and imagistic diagnosis of this very rare, potentially avoidable cause of right heart failure in patients with previous cardiac surgery.
COMPARATIVE TRANSCRIPTOME ANALYSIS OF TWO CLOSELY RELATED BEGONIA SPECIES REVEALS DIVERGENT PATTERNS IN KEY LIGHT-REGULATED PATHWAYS
Authors: Emelianova Katie , Kidner Catherine
Published: August 2022

Begonia is one of the most diverse angiosperm genera, comprising more than 2000 described species. The wide morphological and ecological range represented in the genus makes it a good model for studying the generation and maintenance of diversity. Previous research has shown that strong population structure, poor seed dispersal, and high levels of drift contribute to high rates of speciation and morphological variation. In the present study, we used transcriptomics to compare two closely related but morphologically and ecologically divergent species, Begonia conchifolia A.Dietr. and B. plebeja Liebm., to identify genes putatively involved in ecological divergence. Using publicly available multitissue RNA-seq data, we asked what genetic pathways show species-specific patterns of divergence between our two study species. The results of differential expression and gene ontology enrichment analyses showed species-specific enrichment of light-regulated functions in Begonia plebeja. Concomitant enrichment of ethylene and jasmonate pathways in Begonia plebeja indicate an increased shade avoidance response, suggesting that light availability may be a key factor in the divergent adaptation of B. conchifolia and B. plebeja.
MENINGKATKAN LITERASI DASAR SISWA SEKOLAH DASAR DENGAN PENDEKATAN UMPAN BALIK DAN BACAAN BERBASIS BUDAYA
Authors: Agustian Murniati , Marantika Akhila Maureen
Published: August 2022

Budaya membaca dan literasi siswa di Indonesia masih rendah, ini terlihat dari hasil beberapa penelitian tentang membaca.  Kecepatan membaca dan pemahaman membaca yang rendah, sangat terkait dengan metode yang diterapkan guru, dan ketersediaan buku-buku yang menarik.  Guru disarankan harus lebih meningkatkan minat membaca dengan  menggunakan metode yang variasi.  Pemanfaatan buku – buku yang menarik seperti buku dongeng, cerita rakyat dapat membantu merangsang pembiasaan siswa dalam membaca. Tahun 2016 terobosan besar untuk mendorong tumbuhnya minat baca dan pembentukan karakter siswa telah dilakukan melalui Gerakan Literasi Sekolah (GLS).  Kegiatan wajib siswa adalah melakukan 15 menit membaca sebelum jam pembelajaran dimulai. Sayangnya, masih ada sekolah yang belum melaksanakan GLS yang sesuai dengan semestinya, ada kendala dan kesulitan seperti memperoleh buku dengan gambar yang menarik.  Salah satu sekolah yang belum sempurna kegiatan literasinya adalah SDN PULAU KELAPA 01 PAGI Kelurahan Pulau Kelapa. Kepala sekolah mengatakan bahwa litetasi masih terseok-seok. Pengabdi  tertantang untuk melakukan pengabdian masyarakat dengan tujuan memberikan   pelatihan agar guru mampu: melaksanakan program GLS dengan memberikan umpan balik kepada siswa dan pemilihan buku yang sesuai dengan kebutuhan siswa. Hasilnya guru melaksanakan GLS dengan waktu lebih dari 15 menit karena siswa diminta menulis, memberikan umpan balik, meminta siswa melanjutkan di rumah dan keesokan hari dibahas kembali. Siswa termotivasi menulis karena ada umpan balik dari guru. Ada  peningkatan hasil membaca siswa dilihat dari perkembangan menulisnya. Minat baca siswa belum terukur karena membutuhkan proses panjang, tetapi terlihat bahwa siswa mau membaca bila ditugaskan guru dan memilih buku yang menarik yaitu buku yang terkait dengan budaya
PERENCANAAN AREA HIJAU DI PINGGIRAN SALURAN INDUK PERUMAHAN
Authors: Sabtalistia Yunita Ardianti , Susanto Ione , Raharja Vanessa
Published: August 2022

Banten Indah Permai Housing, Unyur, Serang, Banten is one of the housing estates in the city of Serang. Thehousing has a main canal that is quite large with a fairly heavy flow of water. However, unfortunately on theoutskirts of the main canal overgrown with weeds and shrubs that are not maintained. In addition, there is noretaining wall in the main canal. Based on these problems, this PKM aims to design planning drawings whichinclude site plan drawings, sections, and 3D perspectives. The implementation method is carried out in 3 stages for6 months. The first stage is to conduct a field survey (site measurement) and coordinate with partners (BIP housingdeveloper) and several Housing residents regarding green area design concepts and ideas. The second stage is tosubmit designs in the form of working drawings and 3D perspectives to partners. In the second stage, partnersprovide input or ideas for design improvements proposed by the PKM team. The third stage is the submission of theresults of the green area design by the PKM team to partners. The construction of park benches, children's playareas, sports areas, jogging tracks, rocky paths for reflection, retaining walls, park benches, and parks on theoutskirts of the main canal is expected to provide a place for residents to socialize and create fun activities forresidents. in the morning or evening.ABSTRAK
Perumahan Banten Indah Permai, Unyur, Serang, Banten merupakan salah satu perumahan yang ada di kota Serang.Perumahan tersebut mempunyai saluran induk yang cukup besar dengan aliran air cukup deras. Namun, sayangnyadi pinggiran saluran induk tersebut ditumbuhi tanaman liar dan semak belukar yang tidak terawat. Selain itu tidakada dinding penahan tanah pada saluran induk tersebut. Berdasarkan permasalahan tersebut maka PKM ini bertujuanuntuk membuat desain gambar perencanaan yang meliputi gambar site plan, potongan, dan perspektif 3D. Metodepelaksanaan dilakukan dalam 3 tahap selama 6 bulan. Tahap pertama adalah melakukan survei lapangan(pengukuran lokasi tapak) dan berkoordinasi dengan mitra (pengembang perumahan BIP) dan beberapa wargaPerumahan mengenai konsep dan ide desain area hijau. Tahap kedua adalah melakukan pengajuan desain berupagambar kerja dan perspektif 3D kepada mitra. Dalam tahap kedua, mitra memberikan masukan atau ide untukperbaikan desain yang diajukan tim PKM. Tahap ketiga adalah penyerahan hasil desain area hijau oleh tim PKMkepada mitra. Pembuatan bangku-bangku taman, area bermain anak, area olahraga, jogging track, jalan berbatuuntuk refleksi, dinding penahan tanah, bangku-bangku taman, dan taman di pinggiran saluran induk diharapkanmampu memberikan wadah sebagai tempat bersosialisasi warga dan menciptakan kegiatan menyenangkan bagiwarga pada saat pagi atau sore hari.
HYGIENIC ASSESSMENT OF WORKING CONDITIONS OF PASSENGER VEHICLE DRIVERS IN A METROPOLIS
Authors:   Department of Hygiene and Ecology, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, NUSHERVONI B.KH.
Published: August 2022

Objective: To study the characteristics of the working environment of passenger transport drivers (PTDs) in a metropolis. Methods: The study was conducted at the state unitary enterprises 'Avtobus-1', 'Avtobus-2', 'Avtobus-3', and 'Trolleybus-1' of the city of Dushanbe. 223 drivers of AKIA, ISUZU, LiAZ buses and TIU trolleybuses were involved. Studies of noise and vibration levels at workplaces and dust and gas pollution in driver's cabs were carried out. Results: Noise and vibration levels in the AKIA and ISUZU buses were within the normal range. In LiAZ buses, noise and vibration levels exceeded the maximum permissible levels (MPL) by 9 dB and 12.7 dB, respectively. In trolleybuses, these levels were exceeded by 20 dB and 17.3 dB. The dust concentration inside vehicle cabins of all vehicles was 3.9 to 5.75 times higher than the maximum allowable concentration (MAC). The highest dust concentration was noted in the air at the workplaces of LiAZ buses and TIU trolleybuses drivers – 10.4 mg/m3 and 11.5 mg/m3, respectively. The amount of nitric oxide in the breathing zone of AKIA bus drivers was 10.3 mg/m3, and in the cabs of ISUZU buses, it was 10.6 mg/m3. The highest concentrations of nitric oxide were observed in the cabs of LiAZ buses, which exceeded the MAC by 2.7 times. All vehicles' carbon monoxide concentration was 1.4 to 2.3 times the MAC. Conclusion: Noise and vibration levels are increased in older vehicles, while they correspond to the norms in new generation buses. A significant MAC excess of dust and harmful gases in the buses and trolleybuses cabs, especially during the hot season, is mainly due to the attitude of PTDs in Dushanbe, who fail to comply with the driver's cabin sealing recommendations. Keywords: Passenger vehicles, noise, vibration, gas contamination and dustiness of the air.
PREVALENCE OF OBESITY AMONG THE ADULT POPULATION OF TAJIKISTAN
Authors:   Department of Epidemiology, Avicenna Tajik State Medical University, Dushanbe, Republic of Tajikistan, ABDULLOZODA S.M.
Published: August 2022

Objective: To provide the national estimates of the prevalence of adult obesity (OB) in the Republic of Tajikistan according to official statistics in the 2015-2019 period. Methods: OB prevalence among the adult population of the Republic of Tajikistan in the 2015-2019 period was estimated based on the annual reports of the Center for Statistics under the President of the Republic of Tajikistan. The epidemiological analysis included an assessment of the OB prevalence across the studied period, distribution of overweight people by gender and region of residence. Results: The OB prevalence among the adult population between 2015 and 2019 ranged from 25 to 57 cases per 100,000 people, with an increase by 128% across this period. In 2016 the prevalence increased by 23.1%, in 2017 – by 16.7%, in 2018 – by 10.7% and in 2019 – by 43.5%. The highest prevalence of OB was noted among the residents of the capital; during the study period its increase was 69.2% (from 104 to 176 per 100,000 people; p<0.001). The second high OB prevalence was found in the Sughd region, where it showed an increase across the studied period by 186.7%; in 2019 it was 86 per 100,000 compared to 30 per 100,000 in 2015 (p<0.001). The lowest OB prevalence was noted among the residents of GBAO, where it ranged from 3 to 11 cases per 100,000 people (p>0.05). The same trend was observed among the residents of the Khatlon region, where in the study period the increase in the OB prevalence was insignificant (from 6 to 19 per 100,000 people; p>0.05). Analysis of the data showed that during this period, the life expectancy among women increased by 128.2%, among men – by 150%. However, among the males in the 2016-2018 period there was no significant increase in the OB prevalence (p>0.05). People aged 45 years and above had significantly higher OB prevalence than all other age groups (p<0.001) during the study period. Only in 2016 there was no significant increase (p>0.05) of the OB prevalence among the elderly population (75 and above). Conclusion: The analysis of the data obtained showed that in the Republic of Tajikistan, the OB prevalence among the adult population in the study period ranged from 25 to 75 cases per 100,000 people and increased by 128% between 2015 and 2019. Primary health care facilities should develop a national registry of obese people and provide clinical and epidemiological monitoring of the overweight population. Promoting a healthy lifestyle, healthy diet and physical exercise of the population through the media will improve the health level and quality of life of the population. Keywords: Obesity, epidemiology, prevalence, risk factors, healthy lifestyle.
Perbandingan Efektivitas Klinik Simvastatin dan Atorvastatin Terhadap Profil Lipid Darah: Studi Kasus di Rumah Sakit Universitas Hasanuddin
Authors: Latif Wenry Deston , Aswad Muhammad , Bahar Muh. Akbar
Published: August 2022

Simvastatin dan atorvastatin merupakan obat golongan statin yang bekerja dengan menghambat enzim HMG CoA reduktase. Tujuan penelitian ini adalah mengevaluasi efektivitas klinik simvastatin dan atorvastatin dalam mempengaruhi profil lipid darah pasien dislipidemia di Rumah Sakit Universitas Hasanuddin Makassar. Penelitian ini merupakan studi cross sectional menggunakan data rekam medik pasien dislipidemia yang menggunakan simvastatin 10 mg dan atorvastatin 20 mg selama periode 2017-2020. Efektivitas obat golongan statin dinilai dari perubahan nilai LDL, TC, TG, dan HDL sebelum dan setelah penggunaan obat. Analisis regresi linear digunakan untuk menilai perbedaan efek simvastatin dan atorvastatin terhadap parameter lipid darah. Dibandingkan dengan simvastatin, perbedaan efek atorvastatin terhadap nilai LDL, TC, TG dan HDL, berturut-turut adalah 12,11±20,60 (95% Cl: -28,90-53,21), -11,70±11,30 (95% Cl: -14,84-38,24),  -5,02±11,54 (95% Cl: -28,04-18,00) dan 0,42±4,04 (95% Cl: -7,65-8,48). Pasien yang menggunakan atorvastatin memiliki nilai akhir TC, HDL dan TG yang lebih baik dibandingkan simvastatin. Sementara pasien yang menggunakan simvastatin memiliki profil nilai akhir LDL yang lebih baik dibandingkan simvastatin. Hasil analisis statistik menunjukkan perbedaan yang tidak bermakna yang disebabkan karena terbatasnya jumlah pasien. Oleh karena itu, diperlukan studi dengan sampel yang lebih besar untuk melihat perbandingan efektivitas kedua jenis obat statin pada populasi pasien dislipidemia di Indonesia.
Identifikasi Determinan Molekul Interaksi STK630921 pada Interleukin-17A
Authors: Riandono Fransiscus Deddy , Istyastono Enade Perdana
Published: August 2022

Interleukin-17A (IL-17A) merupakan sitokin pro-inflamasi yang terlibat dalam patogenesis beberapa penyakit, antara lain psoriasis, rheumatoid arthritis, kanker, diabetes dan penyakit ginjal stadium akhir. Peningkatan kadar serum IL-17A memberikan petunjuk adanya keterkaitan antara IL-17A pada kejadian nefropati diabetik. Keterkaitan ini juga diperjelas dengan temuan bahwa penghambatan aktivitas IL-17A dapat menurunkan albuminuria, cedera ginjal dan menunda perkembangan nefropati diabetik. Peranan IL-17A ini menjadikannya sebagai pilihan target potensial terapi nefropati diabetik yang sejauh ini bertumpu pada pengendalian optimal sistem renin angiotensin. Penelitian ini bertujuan mengidentifikasi determinan molekul interaksi STK630921 pada IL-17A. Penelitian dilakukan dengan penambatan molekul STK630921 pada protein IL-17A, dilanjutkan dengan simulasi dinamika molekul selama 15 ns. Identifikasi determinan molekul dilakukan menggunakan bantuan perangkat lunak PyPLIF-HIPPOS terhadap hasil simulasi dinamika molekul. Penelitian ini berhasil mengidentifikasikan asam-asam amino yang berperan penting yaitu His29, Trp67, Asn27, Lys114 dan Glu95 dengan interaksi aromatik dan interaksi hidrogen sebagai jenis interaksi yang berperan pada aktivitas STK630921 pada struktur protein 4HR9.
ANALISIS SEMIOTIKA KOMUNIKASI PADA BARONG BRUTUK DI DESA TRUNYAN KINTAMANI BANGLI
Authors: Komang Dyah Setuti  , I Wayan Wastawa  , I Nyoman Ananda
Published: August 2022

Barong Brutuk is an ancient sacred art that our ancestors passed down way before Hinduism was introduced to Indonesia. It is still practiced and observed today by the people of Trunyan Village in Kintamani Bangli. This research is conducted in order to know (1) the symbols that used in Barong Brutuk, (2) the communication function of Barong Brutuk, (3) the meaning of communication semiotic from sender to the receiver of message. This research is a qualitative research, that using the theory of communication semiotic, theory of religious communication, and theory symbolic interaction. Analytical techniques with hermeneutic analysis. Based on the results of the analysis and discussion, it came to our conclusion that the symbols used in Barong Brutuk in Trunyan Village consist of mask (tapel), kraras leaves, and whip. The mask symbolizes the meeting of the god Trunyan with his future consort, it is interpreted as the meeting of man and women led to believe to be the start of human life. The kraras leaves symbolizes the soil fertility, protecting the environment and the prevention of natural disasters. The belief of self-sacrifice as a means of healing disease, the hope of obtaining offspring is symbolized by the whip. Barong Brutuk has many purposes and uses such as communication, as a means of pleasure, and entertainment for the community, it also reflects on the Trunyan Villages identity as an integrative tool. It’s a method of healing, education and integration during a time of chaos.
Moderasi Beragama sebagai Kekhasan Hidup Berbangsa
Authors: Kinasih CL Tindra Matutino
Published: August 2022

Sometimes in life it is easy for people to blame others, any circumstances or objects are easy to blame. Envy, jealousy, suspicious are traits that are currently often seen in social phenomena. 2022 as a year of moderation is considered a utopian ideal for some, and others are optimistic about achieving it. The problem is what causes us to be pessimistic or optimistic about achieving it? In this study, I use a reflective study to look at the basis of Indonesian human life by reflecting on the Encounter of Hinduism in Penghayatan Kebatinan in Javanese Culture. People who have been able to find the true essence in themselves then that person will get salvation. When people have found themselves, people will accept others. By being able to accept others, then the hope of tolerance can be realized. The life history of the Javanese is a witness to how the moderation movement as an embodiment of national dignity has become a basis that has been lived for a long time. The moderation movement is something that is far and away from Indonesia. From this narrative and writing, it can be seen that moderation is a form of dignity and the breath of national life. Openness to external elements without authenticity is a manifestation of the dignity of Life. The ideal of maintaining harmony is the basic philosophy of Javanese people in living life.
KOMUNIKASI ANTAR BUDAYA MASYARAKAT HINDU-MUSLIM DALAM MENJAGA KERUKUNAN UMAT BERAGAMA DI DESA SINDUWATI KECAMATAN SIDEMEN KABUPATEN KARANGASEM
Authors: I Gusti Ngurah Dedy Hermawan  , D.E Relin , Ida Bagus Candrawan
Published: August 2022

Communication in this study is defined as a meeting between several religious cultures in an area, both communication that takes place in one direction and two-way communication that depend on each other. This communication later forms a formula, a pattern that is carried out by the community in responding to the various cultures that are carried out by each of them. The application of this multicultural concept can be taken as an example to the Hindu community in Sinduwati Village, Sidemen District, Karangasem Regency, which can impact multiculturalism in real life, in its concrete form, namely the existence of cultural communication between the Hindu community and the Muslim community in the village. This can be seen from the way they parallel and respect other teachings openly.

This research was conducted in Sinduwati Village, which is located in Sidemen District, Karangasem Regency. His writing is limited to Intercultural Communication of Hindu-Muslim Community in Maintaining Religious Harmony. This study used a qualitative-descriptive type of research. Descriptive research is generally carried out with the main objective of systematically describing the facts and characteristics of the object or subject being studied appropriately. Data were analyzed by carrying out a series of activities, namely data reduction, presenting, and drawing conclusions. The three steps, both reduction, presentation and conclusion are steps that are integrally interrelated as an analysis circle so that finally the analyzed data can be presented as a research report.

Hindu-Muslim Cultural Communication in Sinduwati Village, related to every religious believer should fully believe and fully trust the truth of the religion he embraces. Religion is able to act as a tool to build solidarity as well as high loyalty for its adherents. Plurality is something that cannot be denied or avoided anywhere and by anyone. The number of Muslim population in Sinduwati Village is relatively small (minority) but the people of Sinduwati Village have never carried out activities that deserve to be said to injure inter-religious harmony between Hindus and Muslims that has existed for a long time. The ancestors of the Hindus in the village of Sinduwati believed that this difference was a gift from God, considered as one of the manifestations of the teachings of God in their respective religions.

Keywords: Intercultural Communication, Hindu-Muslim Society, Maintaining Religious Harmony
PENGARUH PENGGUNAAN METODE PEMBELAJARAN CROZZWORD PUZZLE TERHADAP HASIL BELAJAR IPS SISWA KELAS V SD INPRES PANAIKANG I/1 KOTA MAKASSAR
Authors: Wahyuni Malik Sr , Azis Muhammad , Yusal Sri , Yahya Muh.
Published: August 2022

Jenis penelitian ini menggunakan penelitian eksperimen dengan metode Pre- eksperimen yang dilaksanakan dari tanggal 08 Maret 2021 hingga 31 Mei 2021. Subjek penelitian adalah guru dan siswa kelas VB. Pengumpulan informasi dilakukan melalui observasi, wawancara, dan dokumentasi. Desain penelitian yang digunakan dalam penelitian ini adalah one group pretest-posttest design. Dalam desain ini, sebelum perlakuan diberikan terlebih dahulu sampel diberi pretest (tes awal) dan di akhir pembelajaran sampel diberi posttest (tes akhir). Sedangkan keabsahan informasi diuji dengan triangulasi metode dan sumber.

Hasil penelitian menunjukkan bahwa berdasarkan uji hipotesis yang telah dilakukan dapat disimpulkan bahwa penggunaan media pembelajaran crossword puzzel (teka-teki silang) memiliki pengaruh terhadap hasil belajar IPS siswa kelas V B SD Inpres Panaikang I/1 setelah diperoleh tHitung = 16,22 dan tTabel = 2,030 maka diperoleh tHitung > tTabel atau 16,22 > 2,030.
INFLUENCE OF PUBERTY ON THE ACTIVENESS OF STUDENT LEARNING IN CLASS V MADRASAH IBTIDAIYAH BELITANG SUBDISTRICT EAST OKU COUNTY
Authors: Badawi Jami Ahmad , Deni Indrawan , Muh Miftahurrazikin , Andi Prastowo
Published: August 2022

Pubertas adalah masa ketika individu mengalami perubahan fisik, psikis dan pematangan fungsi organ seksual. Permasalahan dalam penelitian ini adalah apakah ada pengaruh pubertas terhadap keaktifan belajar siswa di kelas V Madrasah Ibtidaiyah. Metode penelitian yang digunakan pada penelitian ini yaitu penelitian kuantitatif dengan jenis survey. Penelitian ini menggunakan dua tempat, yaitu kelas V MI Bustanul Ulum Wonotirto dan MI Islamiyah Sidorahayu yang berada di kecamatan Belitang yaitu sebanyak 33 peserta didik. Teknik pengambilan sampel menggunakan teknik sampling sistematis dengan jumlah sampel 27 peserta didik. Hasil penelitian persentase pubertas siswa kelas V sebesar 40.7% tinggi dan 40.7% sedang sebanyak 22 peserta. Persentase keaktifan belajarnya 55.6% sebanyak 15 peserta didik dalam kategori sedang. Dari hasil uji hipotesis diperoleh bahwa nilai signifikan sebesar 0.00 ≤ 0,05 maka Ha diterima dan Ho ditolak, artinya ada pengaruh yang signifikan antara pubertas terhadap keaktifan belajar siswa kelas V Madrasah Ibtidaiyah Kecamatan Belitang. Dijelaskan besarnya presentase pengaruh variabel pubertas (X) terhadap variabel keaktifan belajar siswa (Y) yaitu R Square sebesar 0,431. Berarti dapat disimpulakan bahwa terdapat pengaruh pubertas terhadap keaktifan belajar siswa kelas V yaitu 57% > 43%.

Kata Kunci: Pubertas, Keaktifan Belajar Siswa.
Anggah-Ungguhing Basa Bali dalam Pembelajaran Drama di Kelas X SMK Negeri 3 Tabanan Tahun Pelajaran 2019/2020
Authors: Tresnawati Ni Made Ari
Published: August 2022

The skill of speaking in Balinese is closely related to the learning material of anggah-ungguhing basa Bali or sor singgih basa Bali. The use of Balinese language in vocational high schools can be taught through learning Balinese drama. The problems in this study are (1) the use of Balinese language in teaching drama in Class X SMK (Vocational High School) Negeri 3 Tabanan in the 2019/2020 academic year, (2) the obstacles faced in the use of Balinese language teaching in drama learning in the Class X SMK Negeri 3 Tabanan for the academic year 2019/2020, and (3) the strategies used to increase the use of Balinese language in teaching drama in Class X SMK Negeri 3 Tabanan for the academic year 2019/2020. This study concludes that in learning drama, students can use all types of anggah-ungguhing basa Bali, but there are still some errors in their use. Constraints experienced by students in the use of anggah - ungguhing basa Bali in drama learning are the lack of mastery of Balinese alus vocabulary, difficulty understanding characters in traditional Balinese drama scripts, and online learning systems. Learning strategies that can be used by teachers of Balinese language subjects in an effort to improve student's ability to understand the use of Balinese anggah - ungguhing basa in drama learning are innovative learning strategies that are integrated with elements of 21st century learning. The innovative learning strategies that can be developed by teachers including designing innovative learning, implementing innovative learning models, and utilizing digital learning.
Hakikat Tri Kona Dalam Lontar Ganapati Tattwa
Authors: Wiraputra Anak Agung Gede
Published: August 2022

In today's life, literary works in the form of lontar still exist as a guide in carrying out religious activities, especially for the Hindu community in Bali. One of the tattwa lontars that became an important work in terms of religious knowledge is the Lontar Ganapati Tattwa. This paper attempts to analyze the nature of the Tri Kona teachings contained in Lontar Ganapati Tattwa with a set of semiotic and religious theories supported by content analysis and descriptive analysis methods. The results of the analysis show that Lontar Ganapati Tattwa is a type of philosophical literary work which contains the essence of secret teachings related to the three omnipotence of God called Tri Kona, namely utpati 'creating', sthiti 'maintaining', and pralina 'melting'. The nature of utpati 'creation' is shown through the description of the process of creating the universe called macro realm/bhuana agung and the micro realm/bhuana alit. The essence of Sthiti 'maintaining' is explained through the description of the meaning of Shiva Linga as a place for the atman to always animate and protect every creature in the universe. The essence of pralina is presented through secret teachings about liberation 'moksa' which is the main life goal of every Hindu religious person. If someone wants to explore the three secret teachings of the Lontar Ganapati Tattwa, it is necessary to clean the heart and purity of the soul and be accompanied by the guidance of a spiritual teacher who always gives advice and advice, so that a complete understanding and perfect implementation will be achieved.
Membangun Pendidikan Karakter Dalam Drama Gong “Ni Diah Tantri” di Live Streaming TVRI Bali Pada Tanggal 24 April 2021, 1 Mei 2021, dan 8 Mei 2021
Authors: Suwiti Ni Nyoman
Published: August 2022

This paper uses a qualitative approach because it aims to describe the behavior of a person or a situation in a certain place in detail and in depth in the form of a narrative. Data collection techniques through external participation and documentation study which contains documents in the form of art works that were filmed In Key studies (in Satori and Komariah,2020:144-145) external participation is observations made via radio, television or reading in libraries. In today's technology there is no doubt that external participation is a fairly effective tool to help writers clarify and record events in gathering the required data. The data obtained were then analyzed by applying the semiotic theory. The author will later interpret the character values contained in the gong drama "Ni Diah Tantri" which is broadcast through Live Streaming TVRI BALI on April 24, 2021, May 1, 2021, and May 8, 2021.
Penerapan Pola Pengajaran Bahasa dan Sastra Daerah Bali sebagai Penguatan Kecerdasan Afektif, Kognitif dan Psikomotorik Peserta Didik
Authors: Perni Ni Nyoman
Published: August 2022

Application of pattern language teaching and literature area of Bali is seen very important applied in of all potential and existing intelligence in learners. As it known, that every participant has a range of student potential and intelligence who strived to be developed early on so that they can grow and develop optimally. As Bloom's taxonomy refers to, that there are three aspects that should be in students in learning, i.e. aspects of apectif-related behavior, cognitive-related knowledge, intellect and related psychomotor skills. So, these three aspects that influence the development of maximum mental attitude, behavior and abilities of learners, so that the purpose of education can be achieved. Pattern language learning and literature area of Bali is pattern learning based on the application of language and literature area of Bali as the local value and charge implemented in learning. The pattern became a cornerstone of learning with student-centered approach as learners and teachers as educators.
Numeral Classifier Bahasa Bali: Suatu Kajian Tipologi Linguistik
Authors: Putra Dwi Mahendra , Mahardika I Putu Permana , Paramitha Ni Made Ayu Susanthi Pradnya , Dwijayanthi Ni Made Ari
Published: August 2022

This research is an of intralingual typology in the form of a numeral classifier in Balinese. The main theory used in this research was the theory of classifier proposed by Aikhenvald (2000). The data was collected by the observation method. Meanwhile, the data were analyzed by grouping the obtained data into the types of numeral classifier proposed by Aikenvald (2000) and Lyons (1977). Based on the result of data analysis, there are types of numeral classifiers of the Balinese, namely the individual, the size, the volume, and the hour numeral classifier. The individual classifier used for count individual object which consisting of bidang, bungkul, ijas, tukel, ukud. The size of a numeral classifier can be stated with fingers and a human hand. The volume numeral classifier used for unit mass measurement, such as catu, cééng, and céntong. The hour numeral classifier used for to stated dauh ‘hours’, which consisting of dauh pisan, dauh ro, dauh tiga.
Verba Membawa “Ngaba” dalam Bahasa Bali Kajian Metabahasa Semantik
Authors: Artini Ni Kadek Dwi
Published: August 2022

Language is a means of communication between humans in everyday life, therefore humans are actors who determine the meaning of the communication. Balinese as the mother tongue used by Balinese people who still pay attention to the order in speaking. This can be seen from the many uses of words in Balinese which in this millennial era are starting to be abandoned. In fact, it is not uncommon for urban and rural people to not understand the language, one of which is verbs. There are many types of verbs in Balinese, but the researcher is interested in one verb, namely the verb carrying "Ngaba" in Balinese which is studied using Natural Semantic Metalanguage (MSA) theory. The verb carrying "ngaba" has 15 equivalent forms, namely as follows " Nyuwun, Natad, Ningting, Ngandong, Ngandeng, Nikul, Nyangkil, Nyunggi, Nyingal, Ngajang, Nampa, Mondong, Nengteng, Ngemel, Natuh ". Each has its own differences which can be seen from the procedure for carrying goods with the tools used, the subject and the object carried. The verb carrying “ngaba” in Balinese has two different meanings, namely doing and happening, which can be explained by the explication technique “X does something to Y”, something that good/bad happens to Y”. This difference in meaning is obtained from the analysis of the original meaning with uncompositional polysemy.