bluuebunny/crossref_metadata_2025 huggingface dataset:
Joint inflammation in patients with primary immunodeficiency
Authors:   Shupyk National Healthcare University of Ukraine, Kyiv, Oshlіanska O.A. ,   SI Institute of Pediatrics, Obstetrics and Gynecology named after academician O.M. Lukyanova of the NAMS of Ukraine, Kyiv, Nadtochiу T.G. ,   SI Institute of Pediatrics, Obstetrics and Gynecology named after academician O.M. Lukyanova of the NAMS of Ukraine, Kyiv, Volokha A.P. ,   Shupyk National Healthcare University of Ukraine, Kyiv, Tolkach S.I. ,   SI Institute of pediatrics, obstetrics, and gynecology named after academician O.M. Lukyanova of the NAMS of Ukraine, Kyiv
Published: January 2024

Purpose - to analyse the leading markers of primary immunodeficiencies in children with joint syndrome based on a clinical case study. The article presents literature data on one of the immunopathological syndromes - autoimmune syndrome - in children with primary immunodeficiencies. Mechanisms of autoimmunity and frequency of joint lesions are discussed. It is emphasized that mostly lesions of the musculoskeletal system are observed in patients with primary disorders of antibody formation and in certain primary combined immunodeficiencies. It was noted that there are specific features of damage to the musculoskeletal system in various nosological units of primary immunodeficiencies. Basic ideas about modern opportunities and problems of treatment of joint lesions in children with primary immunodeficiencies are given. The main clinical manifestations of Nijmegen syndrome in children are described. A case of joint damage in a child with Nijmegen syndrome is given. Conclusions. The system of treatment of autoimmune pathology in the setting of primary genetically determined disorders of the immune system requires further improvement, given the increasing survival rate of patients with primary immunodeficiencies, and in recent years there is a need to develop consensus recommendations for their management, which will improve their quality of life. The research was carried out in accordance with the principles of the Helsinki Declaration. The informed consent of the patient was obtained for conducting the studies. No conflict of interests was declared by the authors.
State of diagnostic markers of inherited metabolic diseases in newborn: analysis of previous results of neonatal screening in Ukraine
Authors:   SI Institute of Pediatrics, Obstetrics and Gynecology named after academician O.M. Lukyanova of the NAMS of Ukraine, Kyiv, Znamenska T.K. , Holota T.V. ,   SI Institute of Pediatrics, Obstetrics and Gynecology named after academician O.M. Lukyanova of the NAMS of Ukraine, Kyiv
Published: January 2024

Despite the different number of inherited metabolic diseases (HMDs) in the panel of expanded neonatal screening (ENS), each country has its own reference values of diagnostic analytes for HMDs specific to its population. In Ukraine, unfortunately, there are no such reference intervals of marker indicators that are responsible for the realization of certain metabolic disorders. Purpose - to analyse the diagnostic markers of SCD and determine the trend of these indicators for the Ukrainian pediatric population. Materials and methods. Therefore, the article presents the previous results of the ENS with the determination of the trend of laboratory indicators of HMDs specifically for the Ukrainian population of newborn children. During the period of the study, ENS by tandem mass spectrometry was performed for 165 newborns born at the SI «Institute of Pediatrics, Obstetrics and Gynecology named after academician O.M. Lukyanova of the NAMS of Ukraine» during 2020-2022. Results. When analyzing the obtained data, a non-linear correlation dependence of the level of diagnostic analytes, namely long-chain fatty acids, depending on the body weight at birth was noted: in groups of children with low and very low body weight at birth, the average values of indicators C0/(C16+C18); (C14:1/C16); (C18:1/C16); (C18:2/C16) are significantly higher compared to children with satisfactory birth weight. Conclusions. Analytical considerations for the interpretation of ENS results include both the influence of maternal conditions during pregnancy and the influence of factors from the side of the newborn. Positive results of ENS require differential diagnosis between perinatal and hereditary diseases, a number of clarifying studies, and further follow-up. The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of the participating institution. The informed consent of the patient was obtained for conducting the studies. No conflict of interests was declared by the authors.
Risk factors of inflammatory bowel diseases in young children
Authors:   SI Institute of Pediatrics, Obstetrics and Gynecology named after academician O.M. Lukyanova of the NAMS of Ukraine, Kyiv, Shadrin O.G. , Mostovenko R.V. ,   National Children’s Specialized Hospital «OKHMATDYT», Kyiv, Ukraine, Horіanska M.H. ,   SI Institute of Pediatrics, Obstetrics and Gynecology named after academician O.M. Lukyanova of the NAMS of Ukraine, Kyiv, Marushko T.L. ,   SI Institute of pediatrics, obstetrics, and gynecology named after academician O.M. Lukyanova of the NAMS of Ukraine, Kyiv, Kovalchuk A.A. ,   SI Institute of Pediatrics, Obstetrics and Gynecology named after academician O.М. Lukyanova of the NAMS of Ukraine, Kyiv
Published: January 2024

In recent decades, there has been a rapid increase in the incidence of inflammatory bowel diseases in the children's population, especially in the age group under 6 years old. Risk factors significantly affect the reactive response of the child's organism and the probability of a pathology occurrence. Purpose - to analyze risk factors for the development of inflammatory bowel diseases with very early onset in children. Materials and methods. The anamnestic data of 78 examined patients with inflammatory bowel diseases - 17 patients with inflammatory bowel diseases with a very early onset and 61 children with inflammatory bowel disease that debuted over 6 years of age - were studied in detail retrospectively. Results. The anamnestic risk factors that were significantly more often observed in patients with inflammatory bowel diseases with a very early onset compared to children with inflammatory bowel diseases with an onset after 6 years of age included: spontaneous abortion in patients' mothers anamnesis, autoimmune diseases in relatives, the presence of concomitant autoimmune diseases in patients, early introduction of artificial feeding and the presence of an infectious disease just before the onset of inflammatory bowel disease. Conclusions. Taking into account the identified risk factors of inflammatory bowel diseases with a very early onset will ensure the improvement of prevention and early diagnosis of this gastrointestinal disease in young children. The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of the institution mentioned in the work. The informed consent of the children’s parents was obtained for the conducting the studies. No conflict of interests was declared by the authors.
Calcium-sensing receptor protein as a prognostic predictor of asthma formation and exacerbation in young children
Authors:   Kharkiv National Medical University, Ukraine, Kolisnyk V.O. , Odynets Y.V. ,   Kharkiv National Medical University, Ukraine
Published: January 2024

Asthma remains the most common non-communicable disease among children, which often has a chronic course and leads to disability. Particular attention should be paid to the diagnosis of asthma in young children. To date, the calcium-sensing receptor (CaSR) is considered to be one of the specific markers in the development of bronchial obstructive diseases. Purpose - to assess the level of CaSR protein and its significance in preschool children with asthma. Materials and methods. The study included 37 patients divided into 3 groups. The Group 1 - children with mild persistent asthma (n=20), the Group 2 - children with moderate persistent asthma (n=17), the Group 3 - almost healthy children (n=20). The study of CaSR protein levels in the blood serum of patients with asthma was performed twice - in the first 2 days of clinical manifestations of the disease and when remission was achieved. The level of CaSR protein in the blood serum was analyzed by enzyme-linked immunosorbent assay (ELISA). All statistical analyses were performed using StatSoft STATISTICA version 8.0 (Tulsa, Oklahoma) and MedCalc version 17.2 statistical software. Results. There was no significant difference in CaSR protein levels between the Group 1 and the Group 2. The level of CaSR protein was significantly lower in the Group 1 and the Group 2 both in the period of acute and remission than in the control group. The level of the marker in the period of disease flare-up in the Group 1 and the Group 2 was significantly lower than in children of the same groups in the period of remission. Conclusions. In all patients with asthma, the level of CaSR protein at the acute stage of the disease is lower than at the remission stage, which is obviously associated with its redistribution from the peripheral blood to the smooth muscle of the lungs. The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of the participating institution. The informed consent of the patient was obtained for conducting the studies. No conflict of interests was declared by the authors.
Recurrent respiratory infections in young school-age children and psychological maternal predictors
Authors:   Dnipro State Medical University, Ukraine, Kramarchuk V.V. , Vysochyna I.L. ,   Dnipro State Medical University, Ukraine
Published: January 2024

Recurrent respiratory infections (RRIs) in children remain a pertinent issue in modern medicine. According to literary data, the prevalence of this phenomenon can reach up to a quarter of the child population. RRIs adversely affect a child’s physical development, social adaptation, and give rise to intra-family conflicts. Purpose - to investigate the contribution of psychological predictors from the mother’s perspective in the development of recurrent courses of respiratory infections in their young school-age children. Materials and methods. The study included surveys of mothers (Spielberger-Hanin State-Trait Anxiety Inventory, the Varga-Stolin Parenting Attitudes Test) and their children (R. Temple, M. Dorki, E. Amen “Choose a face” projective test). The main group comprised children aged 5-7 years with RRIs according to the criteria of the 2021 Inter-Society Consensus. The control group consisted of children aged 5-7 years who experienced occasional acute respiratory infections. Results. In our study, 40 families (mothers and children) participated. We found that mothers of children with RRIs had significantly higher levels of state and trait anxiety, as well as a higher score in the “Cooperation” parenting attitude model compared to the control group. In the structure of the anxiety phenomenon in mothers of children from the main group, 43% of cases exhibited high anxiety levels. Additionally, a high score in maternal personal anxiety correlated with a predominant choice of ineffective parenting models. Conclusions. Mothers of children with a RRI have significantly higher levels of situational and personal anxiety (p<0.01). 43% of mothers of children with RRIs exhibit excessively high levels of personal anxiety. Furthermore, more anxious mothers tend to adopt the following parenting models towards their own children: “Little looser”, “Authoritarian hypersocialization” and “Rejection”. The predictive value in the development of RRIs in children is associated with the level of maternal trait anxiety and the psychological portrait of the mother-child relationship, namely the score for by the “Cooperation” model. Data collection and processing were conducted in accordance with the Helsinki Declaration of the World Medical Association regarding ethical principles in medical research involving human subjects. The informed consent of patients was obtained for the studies. No conflict of interests was declared by the authors.
Current trends in individual rehabilitation programs for children with cerebral palsy: a crucial step towards improving quality of life (literature review)
Authors:   Shupyk National Healthcare University of Ukraine, Kyiv, Kyryk O.V.
Published: January 2024

Approaches to treating and rehabilitating children with cerebral palsy now focus on maximizing their environment and increasing their independence in everyday life. The study of different techniques allows us to consider the needs and goals of families when developing individualized treatment and rehabilitation programs, contributing to the optimal development of the child. Purpose - to study the criteria for developing individual rehabilitation programs, analyzing the examination of children with cerebral palsy, evaluating family-centered care, researching multidisciplinary rehabilitation teams, and analyzing the provision of medical and rehabilitation services and their impact on the quality of life of children with cerebral palsy. A comprehensive and structured search of scientific sources in scientometric databases such as PubMed, Google Scholar, Scopus, Cochrane Library, EMBASE, MEDLINE, and specialized journals in pediatrics and neurology was performed to conduct a systematic literature review. The literature search and analysis were conducted over the past 10 years (from 2012 to 2022). For the bibliometric analysis, the method of data analysis using the VOSviewer program was used. Several important aspects related to the provision of rehabilitation services to children with cerebral palsy and their relationship with classification systems and other aspects are considered and analyzed. The influence of the provision of rehabilitation services by a multidisciplinary rehabilitation team on the functional state of children with cerebral palsy according to the level of the classification system of basic motor functions is substantiated. The study also investigated how the provision of medical and rehabilitation services affects the quality of life of children with cerebral palsy. All of these aspects of the study aimed to improve the provision of services to children with cerebral palsy and their functional status and quality of life. Conclusions. The research demonstrates the need for an in-depth analysis of the examination of children with cerebral palsy and the introduction of family-oriented care. It was found that the development of multidisciplinary rehabilitation teams is effective in achieving the best results in developing children with cerebral palsy. The importance of further research to improve individual rehabilitation programs and improve the quality of life of these children is also substantiated. No conflict of interests was declared by the author.
Communication Strategy for Spald-T Development via YouTube in Haurwangi Village, Cianjur Regency
Authors: Utami Yessi Sri , Jamilah Pupu , Cahyana Aria Bagus
Published: January 2024

Domestic wastewater is a complex problem, but it is almost neglected and not managed, let alone a priority by the public and the government. This does not mean that there is no attention or treatment at all, but its management can still be identified as being carried out in inadequate achievements. This study aims to identify how the development communication strategy becomes an innovation that is beneficial for the surrounding community to solve a problem in terms of health that is packaged in development. The Centralized Domestic Wastewater Treatment System (SPALD-T) must begin with determining the right strategy, determined by considering the conditions of the planning area. This research method uses an approach technique with the results of an interview, observation, documentation and with the results obtained, namely the results of development and innovation that are obtained running smoothly. The results in this study that need to be taken are to seek onsite wastewater management because it is considered relevant, while to increase community participation in the development of domestic wastewater it needs to be coordinated by the KSM
Online Media Reporting Model Encourages Society to Migrate to Digital Broadcasting
Authors: Santoso Puji , Sinaga Corry Novrica
Published: January 2024

This research aimed to analyze the implementation of news coverage on the digitalization of broadcasting and explore the online media reporting model for the digitalization of broadcasting in Indonesia. The online media reporting model encourages people to migrate from analogue to digital television platforms. This research employed a descriptive qualitative method to analyze news from the online media www.Detikcom edition November 1, 2022 to November 16, 2022. Additionally, it utilized Nvivo 12+ software for the data analysis. Detikcom was selected as the data source because it had been ranked as one of the top five online news media most accessed by the public, reaching 320.3 million visits. Most smartphone users, approximately 98%, have visited this site. Based on the researchers' analysis, ten media contents of Detikcom reported the transition from analogue to digital television. The research findings suggested that there is a configuration model for online media reporting on broadcast digitalization. In addition, the online media reporting model identifies the dynamics of the shift from analogue to digital television. The dynamic shift is influenced by economic, juridical, technical, and political views. These findings are expected to provide valuable insights for future researchers studying the digital broadcasting ecosystem in Indonesia post-ASO (Analogue Switch-Off) or post-digitalization.
Determinism of Media Technology and Distortion of Siri’ Culture
Authors: Qadaruddin Muhammad , Bakri Wahyuddin , Md Shah Jalihah , Cahyadi Irlan , Sasriani Andini
Published: January 2024

The rapid development of communication technology, particularly in social media platforms such as Facebook, TikTok, and Instagram, profoundly influences the entire human experience. The influence includes cultural shifts among adolescents, precisely distortions to the "Siri" culture that affect their self-concept, self-esteem, and self-image. This qualitative research aimed to analyze changes in the Siri’ culture in communication among adolescents, the impact of communication media technology, and indicators of Siri' character building. The data was collected through observations, surveys, and interviews. The results showed two main findings: first, in the culture of adolescents in Parepare City, Siri’ is interpreted as a local philosophy that emphasizes the importance of maintaining self-respect in the daily style, speech, and behavior. It has a direct impact on the formation of adolescents' self-concept. The second, media technology has a significant influence on cultural changes and adolescents' self-concept (macca, lempu, warani, getting), self-esteem (penggalik), and self-image (malebbi, mekkeade, makanja).
Reduced-Order modeling for Heston stochastic volatility model
Authors: Kozpınar Sinem , Uzunca Murat , Karasözen Bülent
Published: January 2024

In this paper, we compare the intrusive proper orthogonal decomposition (POD) with Galerkin projection and the data-driven dynamic mode decomposition (DMD), for Heston's option pricing model. The full order model is obtained by discontinuous Galerkin discretization in space and backward Euler in time. Numerical results for butterfly spread, European and digital call options reveal that in general DMD requires more modes than the POD modes for the same level of accuracy. However, the speed-up factors are much higher for DMD than POD due to the non-intrusive nature of the DMD.
A numerical approach for a dynamical system of fractional infectious disease problem
Authors: Gürbüz Burcu , Hatipoğlu Veysel Fuat , Gökçe Aytül
Published: January 2024

In this investigation, we study for a dynamical system aimed at elucidating a disease model under the influence of environmental stress from a broad perspective. The model is articulated through both standard differential equations and their Caputo fractional form. Our methodology involves a numerical approach using the Adams-Bashforth-Moulton technique to solve the system of differential equations, including the initial conditions. The existence, uniqueness and convergence of the technique are also briefly discussed. This study aims not only to improve the current technique, but also to introduce a novel design for obtaining numerical solutions to issues discussed in the existing literature, thus paving the way for further research. We also perform a stability analysis focusing on the coexistence equilibrium. In addition, we present visualisations of the results to elucidate the behaviour of the system, time evolution and phase plane plots with respect to specific parameters.
Introduction in third-order fuzzy differential subordination
Authors: Oros Georgia Irina , Oros Gheorghe , Güney Özlem
Published: January 2024

In light of the well-established and widely-used theory of differential subordination, recent works incorporating fuzzy elements into Geometric Function Theory have given rise to the concept of fuzzy differential subordination. Second-order fuzzy differential subordinations were taken into consideration for studies up until this point. The research described in this paper aims to expand the concept of fuzzy differential subordination to third-order fuzzy differential subordination, building on an idea first put forth in 2011 by Jos\'{e} A. Antonino and Sanford S. Miller and still being investigated by scholars today. The key concepts and preliminary findings required for the development of this branch of fuzzy differential subordination are introduced. The class of admissible functions is specified, the fundamental theorems are established and the fundamental concepts of the third-order fuzzy subordination approach are presented. Several examples constructed as applications of the new results demonstrate the applicability of the new findings.
ECONOMÍA CIRCULAR UNA EXPERIENCIA DE INNOVACIÓN
Authors: Luque Martínez Inírida , Ospina Luz Mary , Rodríguez Deisy Andrea , Cerón Mario , Uribe Arévalo Aura
Published: January 2024

El año 2023 está dejando cifras récord de calentamiento global, la comunidad científica alerta sobre los posibles efectos negativos para la supervivencia de especies. En el 2022 la temperatura media mundial fue aproximadamente 1,15°C superior a los datos históricos  (ONU),  no obstante seguimos con el mismo modelo de consumo que ha marcado el desarrollo desde el siglo XX, el uso de materias primas para ser transformado por la industria en productos que luego la población consume y desecha, a esta forma de producir y consumir se le llama el “modelo lineal”;  modelo que debe replantearse y cambiar a un modelo más sensato y con menores impactos ambientales que se denominada “economía circular”. En este modelo se pretende que todo lo que se utiliza en la producción, en particular los desechos, pueden tener otra oportunidad en la cadena productiva, es decir, impulsar el aprovechamiento de recursos y residuos, dándole así al planeta tiempo y oportunidad de regeneración.

La ONU ha declarado una serie de objetivos en la llamada agenda 2030, con la que todos los países miembros deben comprometerse para mitigar los efectos del deterioro ambiental y lograr la sostenibilidad de la vida, son 17 los objetivos y en particular el No. 11 puede orientarse a los postulados de la economía circular: “Lograr que las ciudades y los asentamientos humanos sean inclusivos, seguros, resilientes y sostenibles”.

Este contexto da lugar a investigaciones que ofrezcan alternativas de cambio o soluciones para enfrentar el deterioro ambiental y darle un giro a esta realidad. Este artículo tiene como objetivos divulgar y dar conocer una experiencia empresarial de reconciliación con el entorno a partir de la economía circular, se pretende resaltar cómo la visión empresarial, el compromiso social han sido los impulsores de un modelo de negocio con un cambio de pensamiento. Se realiza como una investigación de tipo cualitativa, descriptiva y documental, mediante la búsqueda de artículos científicos y la entrevista directa, para la obtención de información que permitan entender el proceso de implementación de la ruta de la economía circular diseñada por la empresa GODOS PLAZA CENTER, ubicada en la ciudad de Machala-Ecuador y como resultado final se busca consolidar un caso de estudio.
ENTRE LA ESCRITURA Y LAS VOCACIONES CIENTÍFICAS: UN PUENTE HACIA EL CONOCIMIENTO
Authors: Norman-Acevedo Eduardo
Published: January 2024

El presente artículo destaca la importancia crucial de la escritura científica en la promoción de vocaciones científicas. La capacidad de comunicar de manera precisa y estructurada trasciende barreras lingüísticas, facilitando la comprensión de conceptos complejos. Además de ser un medio de transmisión de hechos, la escritura científica tiene el poder de inspirar a nuevas generaciones a través de relatos que humanizan la ciencia y revelan la apasionante naturaleza de la investigación. Se subraya también su contribución al desarrollo de habilidades críticas, fortaleciendo el pensamiento analítico y la resolución de problemas. La colaboración intelectual fomentada por la escritura científica no solo fortalece la comunidad científica, sino que también inspira a futuros investigadores a participar en una empresa trascendental. En resumen, la escritura científica no solo es un medio de comunicación, sino un elemento crucial para despertar el interés, inspirar vocaciones científicas y contribuir al avance del conocimiento científico.
Meteorological drought assessment and prediction in association with combination of atmospheric circulations and meteorological parameters via rule based models
Authors: SHAKER SUREH Fatemeh , SATTARİ Mohammad Taghi , ROSTAMZADEH Hashem , KAHYA Ercan
Published: January 2024

The development of data-driven models along with the data that are recorded from satellites has made the study of water engineering more attractive. In this study, SPEI values were calculated with the meteorological variables and then a combination of the meteorological variables as well as atmospheric circulation values was considered as a data mining model input for estimating the droughts. The series of the SPEI values for 3-, 6-, 9-, 12-, 24- and 48-month time scales were obtained during 1988-2016. In this study, both M5 Tree model and Associate Rules were used to predict and analyze the meteorological drought at 6 synoptic stations in the basin considering both the atmospheric circulations (NAO, SO, MOgi, MOac, WeMO, Mediterranean, Red, Black, Caspian, and Persian Gulf SSTs) and the meteorological variables (lagged relative humidity, evapotranspiration, average temperature, minimum-maximum temperature and pressure). The results showed that making use of a combination of the atmospheric circulation indices and meteorological variables in the models increases the accuracy of the model and improves the results in a long term period. The best result in the study of drought in Urmia Lake basin is related to SPEI48 (R = 0.85, RMSE = 0.08, MAE = 0.11) and in the association rules the value of the lift index of best rule is 1.32. Although both approaches provided acceptable results, M5 Tree model had a comparative advantage due to simple and practical linear relationships.
A Study on Recognizing the Value of Chestnut (Castanea sativa) Blossom Waste
Authors: ŞAHİN Hüseyin , KOLAYLI Sevgi , KARA Yakup , CAN Zehra , GÜLER Halil İbrahim , ÖZKÖK Aslı , SERDAR Ümit
Published: January 2024

Chestnut (Castanea sativa) blossoms are natural resources that are not put to economic use and that are completely mixed as waste with the soil. To carry out the potential usefulness of chestnut blossoms, this extensive study was designed and it got out some remarkable results. In addition to the phenolic capacity and antioxidant capacity of the aqueous and ethanolic extracts of dried chestnut flowers, the anti-urease activity of these extracts was studied to demonstrate their therapeutic value. The binding interaction of the phenolic substances present in chestnut blossom with urease was shown using molecular docking research. The aqueous extract had total phenolic content of 45 mg GAE/g, and total flavonoid content of 6 mg QUE/g, also rutin was found as the dominant compound by HPLC. IC50 values of urease of the aqueous and ethanolic extracts were 2.55 mg/mL and 4.45 mg/mL, respectively. According to the docking experiments which were important for supporting the idea of anti-urease activity, myricetin and luteolin showed different and effective bounding degrees to the target protein when compared with the reference molecule acetohydroxamic acid. In summary, chestnut flowers are closely rich in phenolic compounds which are responsible for a wide range of biological activities such as antioxidants and urease inhibition, and these blossoms could be evaluated as important potential raw materials for the food.
Relationships between site factors and plant species on eroded marly soils in Southwest Anatolia (Eskişehir/Turkey)
Authors: ARSLAN Münevver , BALPINAR Neslihan , BİNGÖL Mesrur Ümit , CELİK Nejat
Published: January 2024

Natural regeneration of vegetation is prevented in areas of marly soils by drought and soil erosion. In ecological restoration of eroded areas, the selection of suitable plant species is critical. The aim of this study is to assess specific plant species and their ecological characteristics for their ability to thrive under maximum drought in areas with marly soil. The study was conducted on 36 plots in the marly areas of Eskisehir-Bozan, Turkey, during the most drought-prone months, august and September, in 2011 and 2012. Vegetation sampling was conducted according to the Braun-Blanquet method. Fifteen plant taxa with the highest coverage and frequency were identified. Relationships between plant species and environmental factors were determined by correlation analysis. According to the results of numerical analysis, there were relationships between site factors (nitrogen, phosphorus, organic matter, lime, slope, altitude, and radiation index) and 8 plant taxa. The other 7 plant taxa did not show any relationship with environmental factors. The survival resistance of fifteen plant taxa in marly areas is quite high even in the driest months. These plant taxa, which have properties essential for soil protection, can be used in the revegetation studies of marly areas exposed to erosion.
Determination of Potential Groundwater in Van Province Basin using GIS-based MCDM, AHP and Fuzzy-AHP Methods
Authors: ASLAN Veysel
Published: January 2024

Changes in the climate put extreme pressure on the use of groundwater resources. As the worldwide demand for consumption in agriculture, industry and other fields increases, so does the need for modeling and evaluation of the efficiency of groundwater potential and quality. Today, it has gained great importance in groundwater exploration due to the rapid increase in methods based on multi-criteria decision-making studies (such as GIS, AHP, F-AHP, ELECTRE methods) and providing first-hand information about the source for subsequent developments. In the light of this information, this study was carried out in order to model and evaluate the groundwater potential and quality of Van. In order to evaluate the groundwater potential of the Van province basin, remote sensing data with AHP and Fuzzy AHP methods, which are GIS-based MCDM programs, were used. With the help of ArcMap 10.2 program, eight thematic maps were created such as rainfall, slope, soil texture, land use/land cover, geology, geomorphology, drainage density, drainage density and fault density. These thematic parameters were graded and weighted according to their effects on the groundwater potential. Then, five different groundwater recharge potential regions were classified as very good (8%), good (17%), moderate (43.37%), poor (23.03%) and very poor (9.6%). The evidence obtained by validating the results is in line with the flow calculation studies showing that groundwater flows from the south to the northeast, the central part, and the north to the southwest of the basin. The evidence obtained by validating the results is consistent with the flow calculation values showing that the groundwater basin flows from south to northeast, center and north to southwest of the study area. The validation shows that the method applied for the study area gives a significant and reliable result
A Meta-Heuristic Algorithm-Based Feature Selection Approach to Improve Prediction Success for Salmonella Occurrence in Agricultural Waters
Authors: DEMİR Murat , CANAYAZ Murat , TOPALCENGİZ Zeynal
Published: January 2024

The presence of Salmonella in agricultural waters may be a source of produce contamination. Recently, the performance of various algorithms has been tested for the prediction of indicator bacteria population and pathogen occurrence in agricultural water sources. The purpose of this study was to evaluate the effect of meta-heuristic optimization algorithms for feature selection to increase the Salmonella occurrence prediction performance of commonly used algorithms in agricultural waters. Previously collected dataset from six agricultural ponds in Central Florida included the population of indicator microorganisms, physicochemical water attributes, and weather station measurements. Salmonella presence was also reported with PCR-confirmed method in data set. Features were selected by binary meta-heuristic optimization methods including differential evolution optimization (DEO), grey wolf optimization (GWO), Harris hawks optimization (HHO) and particle swarm optimization (PSO). Each meta-heuristic method was run for 100 times for the extraction of features before classification analysis. Selected features after optimization were used in the K-nearest neighbor algorithm (kNN), support vector machine (SVM) and decision tree (DT) classification methods. Microbiological indicators were ranked as the first or second features by all optimization algorithms. Generic Escherichia coli was selected as the first feature 81 and 91 times out of 100 by GWO and DEO, respectively. The meta-heuristic optimization algorithms for the feature selection process followed by machine learning classification methods yielded the prediction accuracy between 93.57 and 95.55%. Meta-heuristic optimization algorithms had a positive effect to improve Salmonella prediction success in agricultural waters despite spatio-temporal variations in agricultural water quality.
Optimization of Inulin Extraction from Chicory Roots and an Ultrafiltration Application to Obtain Purified Inulin and Hydrolyzed Fructooligosaccharides
Authors: SAĞCAN Nihan , SAĞCAN Hasan , BOZKURT Fatih , BULUT GÜNEŞ Ayşe Nur , FAKİR Hüseyin , DERTLİ Enes , SAĞDIÇ Osman
Published: January 2024

Inulin and fructooligosaccharides (FOS) are prominent functional components in the food industry due to prebiotic and other pharmaceutical properties. Inulin is a storage polysaccharide in various plants. FOS are naturally present in various plants and can be obtained by partial hydrolysis of inulin. In this study, ground and sieved chicory roots (Cichorium intybus L.) were used as starting material for inulin extraction under optimized conditions determined by Response Surface Methodology (RSM) with a Box-Behnken design. Optimum inulin extraction conditions from chicory roots were; temperature of 90 °C, extraction time of 30 min., and liquid-to-solid (LS) ratio of 10:1 mL/g. Inulin extract was further hydrolyzed to FOS by enzymatic or acid treatment, separately. Purification of inulin extract and FOS hydrolysate was performed by ultrafiltration with a 10 kDa membrane under the pressure of 2 bar with continuous stirring. As a result, inulin and FOS were obtained at 90% and 76% purity, respectively.
NUMERICAL ANALYSIS FOR EFFECTS OF GRID SPACER VANE ON FLOW-THERMAL CHARACTERISTICS OF TWO PHASE FLOW IN A 5 × 5 ROD BUNDLE
Authors: Dhurandhar Satish Kumar , Sinha Shobha Lata , Verma Shashi Kant
Published: January 2024

The inclusion of a grid spacer with vane is a crucial component in reactor fuel channels. This component is employed to ensure the proper spacing and firmness of the rods during the flow operation. The presence of vane significantly influences the flow mixing and heat transfer enhancement within subchannels. The objective of this study is to conduct a numerical analysis to investigate the effects of grid spacer vane on flow-thermal characteristics of two phase flow. This investigation used a 5 × 5 rod bundle square array. Pitch to rod diameter ratio was 1.33, and grid spacer blockage ratio was 0.16. Eulerian model was used for two phase fluid formulation. Transient simulations were performed for the flow considerations of flow considerations of velocity 4.74 m/s, liquid temperature 583 K, volume fraction 0.35, heat flux 1500 kW/m2, and pressure 15.5 MPa. The shear stress transport (SST) k-ω turbulence mixture model was used to analyze flow phenomena and thermal performance. Computational fluid dynamics (CFD) results have been validated through the comparison with experiment data. Results show that the accumulation of water vapor is greater in the central zone of subchannels compared to the surfaces of the rods. It is also observed that the vanes lead to an increase in the turbulent mixing rate within the subchannels and a notable reduction in the temperature of the liquid is observed within the grid spacer zone.
The Bionic Body: Disability, Technology and Posthumanism
Authors: Romanska Magda
Published: January 2024

This paper looks at the new field of the critical posthuman disability studies and its potential to provide theoretical framework for critical theory’s engagement with modern technologies. How the concept of the bionic body affects representation of the disabled in contemporary culture and, in turn, how representation of the disabled body affects the changing boundaries of what is and what isn’t considered ‘human.’ Historically, the human body, as represented and defined on stage and in art, has maintained a strictly defined visual integrity. Anything not shaped as ‘human’ was typically deemed monstrous (from hybrid mythological creatures to severely disabled ‘elephant men’). Simultaneously, the category of ‘human’ was used to circumscribe the boundaries of belonging and the categories of valuation: some groups, including the disabled were deemed ‘sub-human’ and designated to either be disposed of (as the carrier of ‘life unworthy of life’) or, if possible, to approximate the ‘human’ body. (Romanska 2019: 92-93). Until very recently, the goal of the prosthetics industry was to create limbs that would serve as visual stand-ins for missing limbs. Similarly, the technological capacities of prosthetic limbs were delineated by human capacities: the disabled were to be given as much ‘abilities’ as the non-disabled, but no more. However, this perception of what the disabled body can and should do has changed with technological progress: not only do the newest prosthetics often look as ‘unhuman’ as possible, but their capacities put into question the capacities and limits of the non-disabled body. All of these and other issues that have emerged in recent years at the crossroads of posthumanism, disability, and biomimicry have led to the development of posthuman disability studies, which tries to untangle and reconceptualize the ethical, legal and philosophical boundaries of human enhancement, species belonging, life and death, and human rights. The posthuman biomimicry, and the prosthetic aspects of digital and AI technologies presupposes a form of disabling of the human body: body without any connection to some type of machine is an inferior body.  In this context, understanding the historical dynamics, critical, philosophical, and ethical debates that have dominated disability studies can provide a framework to how we reconceptualize our posthuman, hybrid future in which our existence with the machines that redefine previous hierarchies is inevitable.  
Variation in the realization of Ukrainian back fricatives as onset lenition and non-markedness reducing coda neutralization: a 3D/4D ultrasound study
Authors: Czaplicki Bartłomiej , Cavar Malgorzata
Published: January 2024

A 3D/4D ultrasound analysis of Ukrainian back fricatives provides evidence for onset lenition (debuccalization) and non-markedness reducing place neutralization in the coda (neutralization to the uvular place of articulation). These findings impinge on the role of markedness in predicting synchronic alternations and the direction of sound change. Analyses that rely on markedness as a motivating factor for synchronic patterns of alternations allow for the possibility of coda lenition, but not of onset lenition. However, the analyzed data instantiate debuccalization, a type of lenition, in the onset. Moreover, the observed retraction of place in the coda, resulting in uvular fricatives, is similarly difficult to derive from markedness principles. These findings are not compatible with the view that synchronic alternations must be driven by markedness reduction and suggest that (i) models of synchronic phonology must be designed in such a way as to accommodate segmental alternations that are arbitrary from the point of view of markedness principles, and (ii) reduction of representational complexity cannot be reliably viewed as the driver of neutralization processes.
Identification of Flavonoids, Antioxidant and Antiproliferative Activity of Aqueous
Infusions of Calendula officinalis L., Chelidonium majus L., Teucrium chamaedrys L.
and Alchemilla vulgaris L.
Authors: Bilušić Tea , Šola Ivana , Čikeš Čulić Vedrana
Published: January 2024

Research background. The current changes in the global economy, characterised by the climate crisis and the economic and health impact of the COVID-19 pandemic, have led to a significant demand for medicinal herbs. This trend is expected to increase significantly by 2050. In this study, we investigated the biopotential of aqueous infusions of four medicinal plants: Calendula officinalis, Chelidonium majus, Teucrium chamaedrys and Alchemilla vulgaris.
Experimental approach. The flavonoid analysis of the aqueous infusions of the selected plants was carried out using the RP-HPLC technique. The antiproliferative activity of the prepared aqueous plant infusions was analysed against three human cancer cell lines (MDA-MD-231, T24 and A549), while the antioxidant potential was measured using three antioxidant methods (DPPH, FRAP and Rancimat assay).
Results and conclusions. T. chamaedrys had the highest total phenolics (expressed as GAE (2061±42) mg/L), free radical scavenging activity (IC50=1.9 mg/mL) and Fe(III) reducing antioxidant power (expressed as FeCl2 (9798±27) mg/L). At a concentration of 1 mg/mL, the antiproliferation of T24 by C. majus was 96 % and of MDA-MD-231 cells by A. vulgaris was 75 % after 72 h. After principal component analysis, T. chamaedrys and C. majus were grouped together. Quercetin glucoside and antioxidant capacity (DPPH) contributed the most to differentiate these infusions from the other two.
Novelty and scientific contribution. This study represents a comparative analysis of the biopotential of four medicinal plants. A new RP-HPLC method was developed to separate the flavonoids in the herbal infusions. This is the first report on the presence of kaempferol-3-O-rutinoside in C. officinalis and isorhamnetin-3-O-rutinoside in A. vulgaris aqueous infusion. For the first time, C. majus has been shown to contribute to the oxidative stability of edible oil. Furthermore, this is the first comparative study on the antiproliferative activity of selected medicinal plants against the cell lines MDA-MD-231, T24 and A549.
Optimization of Ultrasound-Assisted Microwave Encapsulation of Peanut Oil in Protein-Polysaccharide Complex
Authors: Bhuva Sachin S. , Dhamsaniya Navnit K. , Marviya Gopal V.
Published: January 2024

Research background. Peanut oil (Arachis hypogaea L.) is a rich source of unsaturated fatty acids. Its consumption has been reported to have biological effects on human health. Unsaturated, especially polyunsaturated fatty acids (PUFA) found in peanut oil are highly susceptible to oxidation, leading to the formation of harmful compounds during processing and storage. The aim of this study is to prevent the oxidation of peanut oil PUFA by encapsulation in a protein-polysaccharide complex using microwave drying.
Experimental approach. The combined effect of corn starch (CS) and whey protein isolate (WPI) was evaluated for ultrasound-assisted microwave encapsulation of peanut oil to prevent oxidative degradation. The effect of independent parameters, viz. CS:WPI mass ratio (1:1 to 5:1), lecithin mass fraction (0–5 %), ultrasonication time (0–10 min) and microwave power (150–750 W) on the encapsulation of peanut oil was evaluated using response surface methodology (RSM). The process responses, viz. viscosity and stability of the emulsion, encapsulation efficiency, peroxide value, antioxidant activity, free fatty acids (FFA), moisture, angle of repose and flowability (Hausner ratio (HR) and Carr’s Index (CI)) were recorded and analysed to optimize the independent variables.
Results and conclusions. The viscosity of all emulsions prepared for encapsulation by ultrasonication ranged from 0.0069 to 0.0144 Pa·s and more than 90 % of prepared combinations were stable over 7 days. The observed encapsulation efficiency of peanut oil was 21.82–74.25 %. The encapsulation efficiency was significantly affected by the CS:WPI mass ratio and ultrasonication. The peroxide value, antioxidant activity and FFA ranged from 1.789 to 3.723 mg/kg oil, 19.81–72.62 % and 0.042–0.127 %, respectively. Physical properties such as moisture content, angle of repose, HR and CI were 1.94–8.70 %, 46.5–58.3°, 1.117–1.246 and 10.48–22.14 %, respectively. The physical properties were significantly affected by surface properties of the capsules. The higher efficiency (74.25 %) of peanut oil encapsulation was achieved under optimised conditions of CS:WPI mass ratio 1.25, 0.25 % lecithin, 9.99 min ultrasonication and 355.41 W microwave power.
Novelty and scientific contribution. The results of this work contribute to the fields of food science and technology by providing a practical approach to preserving the nutritional quality of peanut oil and improving its stability through encapsulation, thereby promoting its potential health benefits to consumers and applications in various industries such as dairy and bakery.