bluuebunny/crossref_metadata_2025 huggingface dataset:
БАРОКНИ ЕП КАО ФАНТАСТИЧНИ РОМАН БОЈ ЗМАЈА СА ОРЛОВИ ЈОВАНА РАЈИЋА
Authors: Цветићанин Марија С.
Published: January 2025

Кроз рад се тематизују сличности и разлике између епа Бој змаја са орлови и барокног епа као жанра, али и између њега и других књижевних врста. Разматра се ауторов однос према историји, колико је тога веродостојног, као и шта је оно што је субјективно унето у текст. Затим се успостављају сличности између епа и народне културе и традиције, такође се додатно приближавају значења симбола змаја и орла, датих насловом спева. Пратиће се како Јован Рајић гради причу, на који начин користи наслеђе античког мита и који је удео фантастике присутан у свему томе. Настојано је проналажење литерарних веза између епоха које су претходиле, као и оних које су уследиле након настанка овог дела. Коментаришу се и културолошка размимоилажења исламског и хришћанских народа, дата из перспективе ауторовог времена. Биће разложен карактер најистакнутијег лика у спеву, као и опште особине зараћених страна. Важно место у раду заузимају оне стилске фигуре које су значајно допринеле целокупном утиску епа на читаоце, а у најважнијим аспектима говорено је и о другим одликама језика у делу. Посебна пажња посвећена је трећем певању као кулминацији спева, док ће се на крају рада видети како је Јован Рајић завршио дело и који је његов значај за целокупну књижевну традицију.
SRBSKÉ ĽUDOVÉ PRÍSLOVIA S LEXÉMOU БРАТ/БРАЋА (BRAT/BRATIA) A ICH DERIVÁTMI
Authors: Chalupová Nina J.
Published: January 2025

Predložený príspevok má lingvokulturologický charakter. Predmetom tohto príspevku je fond srbských ľudových prísloví s lexikálnym motivantom брат/браћа (brat/bratia) a jeho derivátmi, ktorých zbierku urobil V. Stefanović Karadžić. Pozornosť venujeme aj definíciám prísloví a lexiky, ako i otázke, akú úlohu zohráva jazyk v kultúre. Sústreďujeme sa aj na významy lexémy брат (brat) v slovníku Речник српскога језика a na údaje o lexéme брат (brat) v slovníku Обратни асоцијативни речник српскога језика. Cieľom práce je aplikovať opisnú metódu, aby sme získali nové poznatky o srbských ľudových prísloviach. V práci sa zaoberáme analýzou srbských ľudových prísloví s lexémou брат/браћа (brat/bratia) a ich derivátmi a zisťujeme, že príslovia vyjadrujúce kladný význam sa vyskytujú v práci v rovnakom počte ako príslovia, ktoré majú negatívnu konotáciu. Brat sa chápe v srbskej kultúre ako ambivalentný pojem. Východiskovou literatúrou boli príspevky R. Dragićevićovej, J. Dražićovej, J. Jovanovićovej Simićovej atď.
A virada material nos estudos de religião
Authors: Toniol Rodrigo
Published: January 2025

Este artigo consiste em um esforço circunscrito de sistematização dos debates a respeito da chamada religião material. Tal empreendimento se justifica por duas razões. A primeira diz respeito ao crescente interesse dos pesquisadores latino-americanos pelas relações entre religião e materialidade.. A segunda se refere ao fato de que paira sobre as reflexões feitas a partir da religião material duas desconfianças: a de que não há nada de novo em suas formulações, afinal, não é contemporânea as reflexões sobre objetos religiosos; e a de que a atenção demasiada às materialidade obliteraria a atenção às pessoas. Não se trata, portanto, de um texto que pretende esgotar e tampouco fazer uma revisão do campo ou descrever sua gênese. Na primeira parte deste artigo, que compreende as duas primeiras seções, explicito as justificativas teóricas, para os estudiosos do campo da religião material, que sustentam o argumento de que suas contribuições não podem ser reduzidas à mera atenção aos objetos religioso. Na sequência, ainda nesta primeira parte, recorro ao debate sobre representação para diferenciá-lo daquilo que está implicado na virada material, movimento teórico mais amplo no qual a religião material está também implicada. Na segunda parte do texto argumento que a atenção às materialidades religiosas passa, necessariamente, por uma retomada da atenção às pessoas, a partir de seus corpos e de suas experiências. Por fim, numa breve seção conclusiva, aponto para desdobramentos possíveis das formulações apresentadas neste artigo.
Design and Implementation of Current Control for Step Up–Down Zeta H-Bridge Inverter Using STM32F407VET6
Authors: Wijaya Jonathan , Pratomo Leonardus Heru
Published: January 2025

The development of electrical power conversion equipment is increasing, along with the utilization of new and renewable energy sources. Power conversion equipment from DC to AC voltage, known as inverters, is extensively researched and implemented in this sector. These inverters commonly operate as step-down voltage in specific applications used as step-ups with limited operating ranges. A step-up-down inverter with a single power circuit is developed to overcome this issue. Still, the number of power switches used correlates with the complexity of its control strategy. This paper investigates a step-up-down inverter using the Zeta H-Bridge Inverter with the implementation of six power switches. Furthermore, this type of inverter is operated with a controlled output current utilizing the STM32VET407 microcontroller. The control method is derived based on possible operational modes. An HX10-P current sensor detects the output current. It maintains itself according to the current reference by installing a proportional-integral controller. The initial verification utilizes computational simulation with power simulator software, ensuring the system operates as intended. The final stage involves implementation in the laboratory and testing with standardized equipment. The test results meet the IEEE 519 standard, where the output current has a THD of 1.1%.
Smart Village Synergity: Development of tourism villages as an effort to post-pandemic economic recovery
Authors: Praja Wina Nurhayati , Azis Abdul , Gumelar Abih , Fuadin Ahmad , Sudaryat M. Ridwan
Published: January 2025

The Covid-19 pandemic has triggered an economic recession and caused major damage to the health, employment and human welfare sectors. The impact of Covid-19 that occurred in Indonesia needs to be addressed by referring to the SDGs agenda. One of them is increasing growth and development in the economic sector. Especially in developing the economic sector among the community. Therefore, researchers are trying to help economic development starting from the smallest community environment, from MSMEs in rural areas to how they can be given assistance and guidance in creating business incubators which can be done according to the capital they each have. Apart from that, it is adapted to the skills and creativity of the community in exploring various potentials that can be sold and marketed to the general public. Especially in post In the coming pandemic, of course the economic sector will experience various changes. With many aspects of the economy weakening, there are even layoffs in several sectors . The community is expected to be independent in improving the quality of its economy so that its various interests can be fulfilled properly. Therefore, the formation of a business incubator is a program that the community needs to be more focused and clear so as to help the country's economic sector at large. Thus, the aim of the service program that we are carrying out is to develop a tourist village business incubator as an effort to recover the post-pandemic economy. The service method uses an action research approach . The location of the service is in Jalatrang village, Ciamis Regency .
Perioperative Management, Complications, and Outcomes of Shoulder Arthroplasty in Patients with Diabetes Mellitus
Authors: Viqueira Marissa , Stadler Ryan D. , Sudah Suleiman Y. , Calem Daniel B. , Manzi Joseph E. , Lohre Ryan , Elhassan Bassam T. , Menendez Mariano E.
Published: January 2025

» Patients with diabetes mellitus (DM) undergoing shoulder arthroplasty (SA) have a unique risk profile, which must be considered by clinicians.

» The presence of DM as a comorbidity is associated with longer length of stay following SA, greater likelihood of nonhome discharge, and a higher rate of 90-day readmission.

» Though the incidence is low, patients with DM are at an increased risk of serious postoperative cardiovascular complications, such as pulmonary embolism, venous thromboembolism, and myocardial infarction.

» DM has generally been associated with increased risk of postoperative infection. The optimal hemoglobin A1c threshold in patients undergoing SA remains inconclusive. When extrapolating from lower limb arthroplasty, the literature indicates that this threshold is most likely in the range of 7.5% to 8%.

» Patients with DM are more likely to require revision surgery after SA and report lower postoperative satisfaction.
Les lieux du livre chez Zola: espaces transgressifs et mondes alternatifs
Authors: De Viveiros Geneviève
Published: January 2025

En se voulant une étude des milieux, le roman zolien est un roman topographique. Cet article explore la représentation d’un espace romanesque peu étudié dans l’œuvre de Zola : les lieux du livre et de la lecture. Les romans de Zola mettent en scène des personnages-lecteurs qui font bon ou mauvais usage de livres qu’ils rangent, déplacent ou lisent dans d’étranges circonstances et des lieux parfois surprenants. Associés au désordre, au secret, au corps, au mouvement, ainsi qu’à des mondes utopiques, les espaces liés au livre dans La Fortune des Rougon, La Curée et Pot-Bouille sont symboles de transgression. L’analyse des lieux du livre dans ces romans permet de mettre en lumière une définition de la littérature perçue comme symbole de liberté dans l’imaginaire zolien.
Role of single and mixed culture of Pseudomonas aeruginosa and Serratia ficaria in utilization of petroleum wastes of Dora- refineries.
Authors: Hussein Amal A. , Hassan Shatha S.
Published: January 2025

The ability of single and mixed bacterial culture to utilize Dora-refineries petroleum wastes was compared. Pseudomonas aeruginosa and Serratia ficaria mixed culture consumed the wastes better than the single bacterial cultures. The highest log. number of viable cells in mixed culture was 6.842 , while in single bacterial cultures it was 6.683 and 5.631, respectively. after 3 days in API medium containing the refinery wastes.
The effect of some environmental conditions on the degradation of petroleum wastes was studied included aeration , NaCl concentration , pH and temperature. The growth of bacteria in the agitated culture was higher than stagnant culture the log. of cell no. was 6.021 in the first culture. The highest log. of cell no. stagnant culture was 5.771. Pseudomonas aeruginosa AA22 and Serratia ficaria AA39 were able to grow in medium containing 5 , 7 % NaCl , they favorite pH 7. The mixed culture of the two bacteria grew well of 45 oC.
RNA translational regulation by CPEB4 orchestrates platelet function and pathophysiology
Authors: Navarro Pilar , Hurtado Begoña , Gibert Joan , Vázquez-Bellón Núria , Aresté Cristina , Sánchez-Belmonte Agustín , Ximénez-Embún Pilar , Martínez-Bosch Neus , Muñoz Javier , Tàssies Dolors , Reverter Joan Carles , Morales Albert , Méndez Raúl , Malumbres Marcos , de Frutos Pablo García
Published: January 2025

Platelets are highly specialized anucleate cells that play crucial roles in haemostasis, inflammation and disease. Recent data suggest that mRNA translational control is the primary mechanism of gene regulation in platelets. This study unveils a novel pathway to control mRNA translation and protein expression in platelets via the mRNA binding protein CPEB4. We found high CPEB4 expression levels in human and mouse platelets, colocalizing with cytoskeletal proteins. In vivo loss-of-function studies, using the megakaryocytic lineage-specific Pf4-Cre transgenic mice crossed with a strain containing loxP-flanked CPEB4 (Pf4+:Cpeb4–/– mice), revealed a significant reduction of platelet activation and aggregation. These effects were specific to mature platelets, as CPEB4 deficiency did not significantly impact megakaryocytopoiesis. Functional assays, including tail bleeding and collagen-induced embolism, demonstrated impaired coagulation in Pf4+:Cpeb4–/– mice compared to controls. Furthermore, proteomics analysis of resting and activated platelets from Pf4–:Cpeb4+/+ and Pf4+:Cpeb4–/– mice identified a molecular signature of proteins and networks regulated by CPEB4, including those involved in haemostasis and platelet clearance. Our study reveals CPEB4-mediated mRNA translational regulation as a novel fine-tuning mechanism for modulating protein synthesis in platelets, with significant functional consequences in both physiological and pathological conditions.
Application of Early Continuous Flushing and Drainage with Self- Made Double-Lumen Drainage Tube in Pancreaticoduodenectomy
Authors: Zhang Yi , Lu Yu-Hang , Chen Yi , Huang Ming-Wen
Published: January 2025

Background and Objectives
The incidence of complications following pancreaticoduodenectomy (PD) is notably high. Early postoperative abdominal lavage has been suggested as a potential intervention to reduce these complications. This study explores the safety and efficacy of a self-made double-lumen drainage tube by comparing the incidence of complications after PD using different drainage tubes.
Methods
A retrospective study was conducted to analyze the clinical data of patients who underwent PD at our medical center from 2019 to 2022.
Results
Pancreatic fistula-related bleeding occurred in 2 cases (3.1%) in the experimental group and 37 cases (11.3%) in the control group, with the experimental group showing a significantly lower incidence of pancreatic fistula-related bleeding (P = 0.045). Abdominal infection occurred in 3 cases (4.7%) in the experimental group and 51 cases (15.6%) in the control group, with the experimental group having a significantly lower incidence of abdominal infection (P = 0.020). The length of hospital stay was significantly shorter in the experimental group (21.73 ± 2.82 days) compared to the control group (23.69 ± 5.37 days) (P = 0.005).
Conclusion
Early use of continuous abdominal lavage with a self-made dual-lumen drainage tube following PD is safe, feasible, and effective.
Exploring Biases Related to the Use of Large Language Models in a Multilingual Depression Corpus
Authors: Pérez-Toro Paula Andrea , Dineley Judith , Iniesta Raquel , Zhang Yuezhou , Matcham Faith , Siddi Sara , Lamers Femke , Haro Josep Maria , Penninx Brenda W.J.H. , Folarin Amos A. , Arias-Vergara Tomás , Orozco-Arroyave Juan Rafael , Nöth Elmar , Maier Andreas , Wykes Til , Vairavan Srinivasan , Dobson Richard , Narayan Vaibhav A. , Hotopf Matthew , Cummins Nicholas , Consortium The RADAR-CNS
Published: January 2025

Recent advancements in Large Language Models (LLMs) present promising opportunities for applying these technologies to aid the detection and monitoring of Major Depression Disorder (MDD). However, demographic biases in LLMs may present challenges in the extraction of key information. This study evaluates commonly used LLMs in the speech health literature, across a cohort comprised of English, Spanish, and Dutch speakers with recurrent MDD to observe the effects of different demographic imbalances. Results indicate demographics indeed influence model performance. Gender showed variable impacts across models, with age presenting more pronounced differences. Model performance also varied across language. This study emphasizes the necessity of incorporating demographic-aware models in health-related analyses. It raises awareness of the biases that may affect their application in mental health and suggests further research on methods to mitigate these biases and enhance model generalization.
Overview of the carrying capacity for shrimp farming sustainability: the case of Bangka Island, Indonesia
Authors: Mardyani Yeyen , Nirmala Kukuh , Bidayani Endang , Syarif Ahmad Fahrul , Nugraha Mohammad Agung , Setiawan Fahri , Riskiana Refa , Febrianto Arief
Published: January 2025

High investment interest in white leg shrimp (Litopaneus vannamei) in the Bangka Belitung Islands Province has been observed in the increasing number of shrimp ponds in the last few years. The management of the rapid growth of shrimp ponds must be environmentally sound to maintain the sustainability of shrimp farming and ensure economic benefits without neglecting ecosystem sustainability. The study was conducted from March to November 2022 in Bangka Coastal, Indonesia. This study aims to assess the carrying capacity of the waters and the sustainability of shrimp farming on the Bangka coast through a mass balance model. The physical aspects of water quality were measured in situ and analyzed in the laboratory using various parameters, including temperature, salinity, dissolved oxygen (DO), pH, nitrite, ammonia, phosphate, biochemical oxygen demand (BOD), and chemical oxygen demand (COD). The results revealed that the quality of the shrimp and all the water parameters were within the threshold value, except for ammonia, which was above the threshold. The mangrove coverage density of the shrimp pond area varies: it is considered low to moderate in the Parittiga coastal region of West Bangka, while in the Tukak Sadai coastal area of South Bangka, it ranges from moderate to high. The average shrimp production on the Parittiga coast reaches 40–69 metric tons year-1, whereas that on the Tukak Sadai coast reaches 50–180 metric tons year-1. Based on mass balance calculation, the potential areas available for developing shrimp farming on the Parittiga coast are estimated 86,60–175,39 hectares and 27,65–45,05 hectares on the Tukak Sadai coast. Consequently, it is necessary to monitor and regulate waste disposal and the installation of wastewater treatment plants (WWTPs) at each shrimp pond, as well as to enhance the capacity of these WWTPs to reduce waste by 80%.
Factors associated with SARS-CoV-2 infection amongst Health Workers in Bamako, Mali: a cohort study from November 2021 to February 2023
Authors: Konaté Drissa , Balam Saidou , Dolo Housseini , Koné Amadou , Traoré Bourama , Kané Fousseyni , Incandela Nathan C , Diallo Dramane , Traoré Abdouramane , Kanté Salimata , Sidibé Mariam , Keita Bourama , Coulibaly Aminatou , Kassé Fatoumata , Tangara Karamoko , Maiga Issoufi Y , Guindo Merepen dite Agnès , Denou Larissa , Konaké Mama Sy , Traoré Mariétou , Dicko Abdoul RA , Keita Naman , Koné Diakaridia , Malle Korotoumou , Coulibaly Yaya Ibrahim , Faye Ousmane , Diakité Mahamadou , Doumbia Seydou
Published: January 2025

Background. Health workers (HWs) are at high risk of SARS-CoV-2 infection due to their frontline role and considered as priority group for COVID-19 vaccination. This study aimed to estimate SARS-CoV-2 infection and COVID-19 incidence rates and identify the risk factors among HWs in Mali to strengthen prevention measures.
Method. A cohort study of 1098 HWs was conducted from November 2021 to February 2023, in six health centers and two university hospitals of Bamako. Sociodemographic and clinical data, nasopharyngeal swabs were collected to determine asymptomatic SARS-CoV-2 infection rate during the cross-sectional surveys. Self-reported COVID-19 cases were collected during biweekly follow-ups. REDCap was used for data management. Mixed-effects Cox regression models and multivariate logistic regression were used to identify the risk factors for SARS-CoV-2 infection.
Results. Amongst 1098 HWs, 34.7% were nurses, 8.2% have had contact with COVID-19 patients, and 18% with COVID-19 samples. A significant change in the rate of SARS-CoV-2 infection (asymptomatic infection) was observed between November 2021 (3.4%), February 2022 (1.3%) and February 2023 (4.8%, p = 0.0001). SARS-CoV-2 21I (36.7%) and 21L (8.2%) Delta variants were observed mainly in November 2021 giving place to Omicron over time. The distribution of SARS-CoV-2 variants was similar in vaccinated and unvaccinated health workers (p = 0.716). Absence of anti-N antibodies (HR=3.98 95%CI, 2.23-7.12), contact with COVID-19 patients (HR=3.85 95%CI, 2.00-7.44]), use of public transport (HR=2.20 95%CI, 1.05-4.61) and participation in public events (HR=7.93 95%CI, 1.03-60.1) were associated with a higher risk COVID-19 confirmed cases (symptomatic SARS-CoV-2 infection).
Conclusion. Results show a high rate of SARS-CoV-2 infection in February 2023, and the risk factors were both in work and community settings.
Combined reconstruction of the middle hepatic vein in the right lobe split liver transplantation
Authors: Lin Zhengwei , Feng Fei , Yu Qi , Ye Yingpeng , Yang Yong , Zhu Hongda , Lu Caide , Fang Jiongze
Published: January 2025

Purpose
There are few studies on the reconstruction of the middle hepatic vein (MHV) in split liver transplantation (SLT) using right lobe grafts. This study aimed to compare the outcomes of patients with MHV combined with right hepatic vein (RHV) reconstruction and those with separate reconstruction.
Methods
Clinical data of 114 patients who underwent SLT from March 2021 to December 2023 were retrospectively collected. We analyzed and compared the postoperative outcomes and reconstructed MHV patency between different modalities of MHV reconstruction in the right lobe SLT.
Results
Forty-five right lobe grafts were reconstructed with the MHV and were divided into two groups according to the type of reconstruction. Group 1 (n = 19) received separate reconstruction, while Group 2 (n = 26) received combined reconstruction. The duration of warm ischemia in Group 2 was significantly less than that in Group 1 (47.9 ± 7.8 vs. 59.7 ± 15.6 min, P = 0.002), and the ICU hospitalization time was significantly less in Group 2 than in Group 1 (2 vs. 3 days, P = 0.022). The rate of complete patency of the reconstructed MHV at 30 days postoperatively was higher in Group 2 than in Group 1 (96.2% vs. 68.4%, P = 0.031). The rates of postoperative complications were comparable between the two groups.
Conclusion
Combined reconstruction of the MHV and RHV in SLT improves the rate of complete patency of the reconstructed MHV, reduces warm ischemia time, and shortens the length of ICU stay.
Quiet Time and Noise-Mitigation Strategies in a Long-Term Care Facilities
Authors: Massarweh Alaa Zuahir , Bakhit Refa Hanish B Z , MOHD NAGWA AHMED BABIKIR , Zaharan Mohammad , Icic Novica
Published: January 2025

Purpose: this research was conducted to examine the significant impact of quiet time and noise-mitigation strategies on reducing noise pollution in the long-term care facility.
Design/methodology/approach: in this quality improvement project, noise intensity within the unit was recorded before rolling out the intervention program. Noise intensity was recorded for 2 hours in the morning and evening shifts and for 6 hours during the night. An average noise intensity was noted for the one week of measurement before the intervention program consisting of quiet time and noise-mitigation strategies. The mitigation approach through the PDSA model involved educating the staff, patients and patients’ family members about mitigation strategies. Staff compliance and satisfaction were assessed using a survey, and noise intensity was measured using the Yacker tracker and recorded between November 2021 and April, 2022.
Findings: at the end of the quality improvement project, the noise intensity within the long term care unit declined from 88dB to 35dB which is within the recommendation of the World Health Organization. The decline was statistically significant (t(12) = 160.103, p = .000). Staff and patients’ satisfaction with noise within the unit also increased from 35% to 78% between, and the improvement was statistically significant at 95% confidence interval (p<.001). Moreover, compliance with the noise reduction behaviors improved significantly over the period of the program (p<.001).
Originality: this research observed the significance of combining education and behavior change methods aligned to the PDSA model to reduce noise levels in the long term care facility.
Analysis of YouTube Videos on Assisted Reproductive Techniques
Authors: Demirtas Selim , Gördük Mehmet Nuri
Published: January 2025

Background
Assisted reproductive techniques (ART) have made significant progress in infertility treatment and have found a wide range of applications with various methods, especially in vitro fertilisation. Today, digital platforms such as YouTube have become an important resource for individuals seeking information about ART. However, uncertainties about the reliability and quality of this content pose a potential risk for viewers. This study aims to assess the quality and reliability of ART-related videos on YouTube.
Methods
76 videos were analyzed by applying elimination criteria from 350 videos uploaded between October 1, 2014 and October 1, 2024. These videos were obtained through YouTube Data API v3 by searching seven different terms related to in vitro fertilization and infertility. In addition to descriptive statistics on video features, the Global Quality Scale (GQS), Modified DISCERN, JAMA and UTvAC scales were applied to evaluate the quality of the videos. Additionally, sentiment analysis was conducted on the comments of the videos.
Results
It was determined that the majority of the analyzed videos were at medium quality level. While the JAMA scores indicate that most of the videos are of low quality, the GQS and Modified DISCERN scores suggest that most videos fall within the medium quality range. According to UTvAC, most videos are just below the high-quality limit. The majority of videos were uploaded by doctor-independent influencers (32.9%), non-governmental organizations (25.0%), and news/media (21.1%) channels. The positive comment percentage was found to be 28%, indicating that the videos were generally poorly appreciated by viewers.
Conclusion
This study revealed that the information quality and reliability of ART videos on YouTube are generally moderate. It is recommended that viewers should adopt a critical approach and turn to reliable sources when evaluating content on ART. The findings of the study show that there is a significant need for improvements in digital health communication and educational content production.
Green Synthesis, Characterization, In Silico Molecular Docking and Biological Evaluation of Imidazolylchalcones as Promising Fungicide/s and Nematicide/s
Authors: Kumar Rakesh , Kaushik Parshant , Tripathi Kailashpati , Godara Rajni , Misra Sameer Ranjan , Kumar Vijay , Mondal Patha Chandra , Jeetram Jeetram , Pankaj Pankaj , Rana Virendra Singh , Shanmugam V. , Khatri Dilip , Shakil Najam Akhtar
Published: January 2025

Chalcones and their derivatives have garnered attention due to their broad-spectrum biological activities. In this study a series of 15 imidazolylchalcone derivatives were synthesized by Claisen-Schmidt condensation of benzaldehydes and 4-(Imidazol-1-yl) acetophenone through ultrasonication as green synthesis. These compounds were characterized by various spectroscopic techniques, namely 1H-NMR, 13C-NMR and LC-HRMS. These molecules were evaluated for their fungicidal activity against Rhizoctonia solani & Fusarium oxysporum and nematicidal activity against Meloidogyne incognita. The result revealed that compound IC-8 ((E)-1-(4-(1 H-imidazole-1-yl) phenyl)-3-(4-benzyloxy)phenyl)prop-2-en-1-one) exhibited the most potent fungicidal activity, with an ED50 value of 0.69 µg mL− 1, significantly lower than the ED50 value (3.57 µg mL− 1) of commercially available hexaconazole 5% SC fungicide against R. solani, while IC-4 ((E)-1-(4-(1 H-imidazole-1-yl) phenyl)-3-(2-bromophenyl) prop-2-en-1-one; ED50 = 119.22 µg mL− 1) showed highest activity against F. oxysporum as compared with the positive control Carbendazim 50% Wettable powder (WP; ED50 = 9.01 µg mL− 1). The compound IC-6 ((E)-1-(4-(1 H-imidazole-1-yl) phenyl)-3-(3-nitrophenyl) prop-2-en-1-one; LC50 = 33.62 µg mL− 1) was found to be most active against M. incognita (LC50 = 31.25 µg mL− 1) after 24 h of inoculation but lesser active than positive control Velum Prime 34.48% SC (Fluopyrum; LC50 = 3.46 µg mL− 1). Molecular docking studies of imidazolylchalcone derivative-based structural isomers were carried out against cutinase of fungi and acetylcholinesterase (AChE) enzyme of nematode as primary targets. The binding potential of target compounds was investigated by using AutoDock Vina. Ligands were ranked according to their binding affinities via BIOVIA Discovery Studio. Ligand-protein interactions strengthened results of biological evaluation that predicted compound IC-8 as the most active with highest binding energy (-8.5 kcal mol− 1) against R. solani, IC-4 (-8.0 kcal mol− 1) against cutinase of F. oxysporum and IC-6 (-9.7 kcal mol− 1) with acetylcholinesterase (AChE) of M. incognita.
Theoretical investigation on heat transfer rate of hydromagnetic transformer oil based multiphase fluid: Comprehensive modeling and computational study
Authors: Nazeer Mubbashar
Published: January 2025

Motivation and objective: The main objective of this research is to investigate the thermal analysis of the magneto two-phase flow of Prandtl fluid with the suspension of silver and hafnium nanoparticles through inclined walls of the channel. The momentum equations are modified under the addition of body forces to consider the impact of magnetic and gravitational forces. The heat equation is also updated with the addition of the heat flux term to capture the thermal radiation effects.
Methodology: The two-phase model is developed in terms of continuity, momentum, and heat equations of fluid and particle phases and uses dimensionless variables to simplify the system of equations. The dimensionless form of equations is solved by using the regular perturbation method in which the second Prandtl fluid parameter is taken as a perturbation parameter and produces the analytical solution. The graphical results revealed many physical aspects under the physical parameters in which the first and second Prandtl fluid parameters diminish the fluid and particle phase velocity distribution.
Outcomes: The suspension of hafnium particles in the base fluid provides more heat to the system as compared to silver nanoparticles. The particle phase velocity distribution is much greater than the fluid phase against all parameters of the study. The magnetic force has an inverse relation with the velocity and thermal profiles of both phases. The two-phase Prandtl fluid model provides 55 %more heat transfer as compared to the single-phase Prandtl fluid model. The two-phase Prandtl fluid model gives 29% greater heat transfer to the system as compared to the phase Newtonian fluid model.
Significance of the study: The current study will help to optimize the industrial thermal management process and to design efficient cooling systems in electronic devices, and in polymer and food processing.
Originality: The topic discussed in this study is new and has not been deliberated before.
Stochastic resonance in Schmitt trigger and its application towards weak signal detection
Authors: Kim Yoonkang , Seo Donghyuk
Published: January 2025

This study explores stochastic resonance (SR) in a Schmitt trigger circuit and its application to weak signal detection. SR, a phenomenon where noise synchronizes with weak signals to enhance detectability, was demonstrated using a custom-designed bi-stable Schmitt trigger system. The circuit's bi-stability was validated through hysteresis curve analysis, confirming its suitability for SR studies. Experimental results revealed SR behavior by analyzing signal-to-noise ratio (SNR) responses to noise amplitude variations. Detection experiments were conducted to determine frequency and amplitude of damping sinusoidal pulses. Frequency detection proved effective, albeit with limitations at low frequencies, while amplitude detection faced challenges due to mathematical complexities. Nonetheless, the study highlights SR's potential for weak signal detection, with proposed enhancements to improve detection accuracy. This work underscores the adaptability of classical SR principles to practical detection systems and suggests future applications in advanced detection technologies, including quantum systems.
Bavachalcone targets TFRC and sensitizes gemcitabine to affect bladder cancer progression through the iron-dependent ATR-CHEK1-E2F1 signaling pathway
Authors: Zhang Zihao , Yuan Chenyue , Ge Qintao , Liu Wangrui , Xu Meng , Wang Mengfei , Feng Tao , Wang Yue , Zheng Shengfeng , Wang Zhongyuan , zhang Wei , Tian Xi , Huang Wei , Chen Ziqi , Tu Chao , Zhang Hailiang , Shi Guohai , Cao Dalong , Shen Yijun , Wang ZiLiang , Ye DingWei
Published: January 2025

Gemcitabine resistance is a critical factor contributing to the recurrence and progression of bladder cancer. In this study, we utilized high-throughput drug screening and bladder cancer organoid models to identify Bavachalcone (Bava) as a sensitizing agent for gemcitabine, thereby inhibiting the progression of bladder cancer. Bava targets transferrin receptor (TFRC) and epidermal growth factor receptor (EGFR), competitively binding to TFRC with transferrin (Tf), which reduces the influx of iron ions and the activity of mitochondrial respiratory chain complexes. Concurrently, Bava inhibits the phosphorylation of TFRC at tyrosine 20 (Y20) by blocking EGFR phosphorylation, thereby stabilizing TFRC on the cell membrane. The combination of Bava and gemcitabine effectively inhibits the repair of DNA damage induced by gemcitabine. Additionally, Bava suppresses the iron-induced ATR-CHEK1-E2F1 signaling pathway and decreases the expression of RRM1, further sensitizing cells to gemcitabine. Studies utilizing patient-derived xenografts of bladder cancer have demonstrated that the Bava-gemcitabine combination significantly inhibits tumor progression. Correlating with clinical data, we found that TFRC and RRM1 may serve as markers of poor prognosis in bladder cancer. In summary, our research has identified specific Chinese medicine monomers that sensitize cells to gemcitabine, elucidated their direct action targets, and highlighted the role of iron ions in tumor development. This work also paves the way for novel drug design strategies that target TFRC to inhibit iron ion influx and mitigate bladder cancer progression.
NARRATIVE AS AN INTERDISCIPLINARY CATEGORY: THE HISTORY OF STUDY
Authors: Shyshkin Maksym
Published: January 2025

The article examines the narrative concept as an interdisciplinary category that plays a key role in understanding and structuring human experience through stories. The main narrative study approaches, developed by leading researchers, in particular Roland Barthes, Paul Ricoeur, Gerard Genette, Franz Karl Stenzel, David Herman and Jane Elliott, are analyzed.
The narrative theory development from the structuralism of the 1960s to modern cognitive, sociological and philosophical research is outlined. Special attention is paid to Genet's narrative three-level model, Ricoeur's concept of meaningful time, Stenzel's typological approach and Herman's cognitive theory. The role of narrative in culture, social relationships, identity and communication is highlighted.
The article also examines the practical narratives application in various fields: media studies, marketing, psychotherapy, education, politics, economics, and digital culture. The authors emphasize the universality of narrative, its ability to integrate knowledge from different disciplines and contribute to the understanding of both individual and social experience.
THE CONCEPT OF MONUMENT IN ENGLISH LANGUAGE: TOWARD A LEXICAL AND SEMANTIC ANALYSIS
Authors: Tatsenko Nataliia , Donik Ivan
Published: January 2025

This article delves into the lexical and semantic analysis of the concept MONUMENT, with a focus on its historical and cultural significance within various linguistic traditions. By employing componential analysis, the study reveals both common and differential semes associated with the lexeme “monument”, highlighting its multifaceted roles as a physical structure, a symbol of memory, and a marker of historical and cultural identity. Common semes such as “remembrance”, statue”, “tombstone”, and “historic significance” underscore the unifying aspects of the concept MONUMENT, while differential semes, including “boundary marker”, “lasting evidence”, “written tribute”, and “exceptional example”, reveal the diverse and multifaceted roles that monuments play in different contexts. Tracing the etymological evolution of the term “monument” from its Latin roots, the research demonstrates how the concept extends beyond its material form to encompass deeper cultural meanings related to commemoration, boundary marking, and exemplary achievements. The study underscores the dynamic nature of monuments, emphasizing their importance not only as cultural artifacts but also as symbolic embodiments of collective memory and identity. In light of ongoing global conflicts and natural disasters, this research also emphasizes the critical need for the preservation of monuments, which are vital to maintaining cultural heritage. Prospective areas for future study include the cross-cultural analysis of the concept MONUMENT and its evolving role in contemporary geopolitical contexts.
GENRE AND STRUCTURAL FEATURES OF M. ONDATZHE'S NOVEL «WARLIGHT»
Authors: Trembovetskyi Pavlo
Published: January 2025

The research focuses on identifying the features of the genre structure of Michael Ondaatje's novel «Warlight». The novel is written in the format of a free retrospective and reflective narrative of the «I-narrator» Nathaniel Williams about the teenage period of his life in London at the end of World War II and in the first post-war decades. The «coming-of-age» story, despite its «chamber» nature, unfolds in the novel in the background of important social and historical events of the modern era and is determined by the complex vicissitudes of the narrator's relations with representatives of different strata of English society in the second half of the twentieth century. The novel consists of two parts, which differ significantly in narrative and poetic paradigm. The first part (6 chapters) is retrospective memories, which are only occasionally interrupted by insertions from the indefinite «present». Instead, the second part (14 chapters) is more of the narrator's fantasy, when he either reconstructs individual episodes of his mother's life from fragmentary stories about her from people who knew her, or imagines how certain events in the past could have unfolded. At the same time, in both parts there is an interweaving of narrative plans that differ in time and space. The protagonist's declared idea that the past never remains in the past is confirmed by the history of his entire life. Reflections on how the past influences the future, shapes and intertwines people's destinies, determine the poetic and stylistic features of the novel. So the specificity of the «coming of age» story is determined by the interweaving of genre and style strategies of bildungsroman, story of self-discovery, spy novel, quest narrative, moral and philosophical novel.
APPLYING DISIGN THINKING PRINCIPLES TO MODERN LEGAL ENGLISH EDUCATION
Authors: Danylchenko-Cherniak Oksana
Published: January 2025

This paper investigates the integration of design thinking principles into modern Legal English education to enhance critical thinking, creativity, analytical skills, and digital literacy among law students. Drawing on theoretical frameworks and practical examples, this study highlights the significance of design thinking in reshaping philological education, focusing on strategies for curriculum integration and the associated benefits for both students and educators. Design thinking, a user-centered and iterative process celebrated for fostering innovation, is positioned as a transformative approach to addressing the evolving needs of Legal English education. The paper explores how the phases of empathizing with learners, defining educational challenges, ideating creative solutions, prototyping instructional strategies, and testing these methods in real-world educational settings can be employed to create engaging, adaptive, and effective learning experiences. By presenting case studies and practical applications, this research demonstrates how design thinking enhances language proficiency, critical reasoning, and legal competencies in Legal English curricula. The findings underscore the potential of design thinking to align Legal English education with the demands of the digital age, fostering interaction, adaptability, and professional readiness. Furthermore, this study advocates for a systematic adoption of design thinking to bridge traditional teaching methodologies and innovative pedagogical practices.
IMPLEMENTATION OF PRAGMALINGUAL TOOLS FOR MANIPULATIVE FAKE NEWS STRATEGIES REALIZATION (on the materials of English Internet media)
Authors: Medvid Olena , Klochko Oleksandr , Stetsenko Oksana
Published: January 2025

The article is devoted to the study of the fake news functional features. The main task of fake news is to falsify real news, which leads to the spread of disinformation/misinformation, which has negative consequences for society. One of the key aspects of fake news is the use of a wide range of pragmalinguistic means to convince recipients of the truth of the information The relevance of the research is based on the fact that fake news is a serious problem of modern society in the period of intensifying information war and manipulative technologies. The methodological basis of the research is the use of semantic-cognitive and discursive approaches to the study of the conceptual content of "fake" (through the lexicographic method, that is the dictionary definition, which extrapolates the semantic load of tht given lexical unit to discursive study); as well as to the study of linguistic means of implementing a fake in news media texts through various types of linguistic analysis (contextual, semantic-syntactic, stylistic, etc). The findings of the study of the fake news pragmalinguistic nature show that linguistic means are able to coordinate manipulation goals through the implementation of emotional arguments, a sense of urgency and significance of the message, the use of a quasi-explicit source of information, decorating it with stylistically colored lexical units for additional attraction of the audience. Comprehending the functioning of these linguistic processes is critical to effective fighting of fake news. increasing the resilience of society.
Governança Corporativa e Valor das Empresas Brasileiras de Capital Aberto: uma análise do Informe de Governança
Authors: Brandão Isac de Freitas
Published: January 2025

Desde 2018 as empresas brasileiras de capital aberto divulgam o informe sobre o Código Brasileiro de Governança Corporativa - Companhias Abertas (informe de governança), indicando quais práticas recomendadas pelo código são adotadas e apresentando justificativas para as práticas não adotadas, em uma abordagem conhecida como pratique ou explique. Este trabalho verificou se a adoção das práticas avaliadas no informe de governança agrega valor para a empresa brasileira. Primeiramente mensurou-se através de índices o nível de adoção às práticas avaliadas no informe de governança de 209 empresas brasileiras no período de 2019 a 2021, totalizando 596 observações anuais. Em seguida analisou-se a relação dos índices com o valor de mercado das empresas e a sensibilidade desta relação a características da empresa apontadas como determinantes dos conflitos de agência: concentração de propriedade, excesso de direitos de voto, rentabilidade, endividamento e tamanho. Os resultados apontam crescente nível de aderência às práticas recomendadas no código, e que este nível está positivamente relacionado com o valor da empresa. Ademais, observou-se que esta relação é mais forte em empresas em que não há excesso de direito de voto dos acionistas controladores, mais rentáveis, menos endividadas e maiores. O trabalho apresenta evidências de que a obrigatoriedade da divulgação do informe de governança pode contribuir para maior adoção de práticas recomendadas e avaliação da qualidade da estrutura de governança das empresas brasileiras de capital aberto, com a ressalva de que a escolha de quais práticas que devem ser priorizadas pelas empresas depende de características do ambiente organizacional.
Efeitos da Consistência do Sistema de Gestão de Desempenho de Recursos Humanos no Engajamento no Trabalho
Authors: Leal Guimarães Duanne Emanuel , Soares Cristiano Sausen , Zonatto Vinícius Costa da Silva
Published: January 2025

A pesquisa tem como objetivo analisar os efeitos da consistência do sistema de gestão de desempenho de recursos humanos (CSGDRH) no engajamento no trabalho, em uma Autarquia Pública Federal Brasileira. O estudo quantitativo, descritivo, caracterizado como uma Survey Single Entity, trabalha com uma amostra de 132 servidores públicos, com no mínimo 8 participações em processos de avaliação de desempenho de pessoal. A relação investigada foi testada a partir da modelagem de equações estruturais. Os resultados demonstram relação significativa e positiva entre CSGDRH e o engajamento no trabalho. Tais achados são convergentes com a literatura e revelam que a consistência tem o potencial de reforçar o alcance dos objetivos propostos pelo Sistema, ou seja, aumenta o suporte à criação e sustentação de altos níveis de engajamento no trabalho. Conclui-se que a CSGDRH precede o engajamento no trabalho, no ambiente da autarquia pública em estudo. A partir da construção da relação entre a CSGDRH e o constructo comportamental do engajamento no trabalho, os servidores públicos passam a compreender melhor os objetivos propostos pelo sistema e o significado social do seu trabalho, pelo aumento do suporte organizacional, que se refletem na criação e sustentação de altos níveis de engajamento no trabalho. O estudo contribui ao apresentar a interlocução da relação, a nível organizacional e individual, entre a CSGDRH e o engajamento no trabalho, de modo a instigar o gestor público quanto à importância da CSGDRH e como esta pode refletir em melhorias dos serviços públicos ofertados à sociedade.
Para além da representação: uma análise semiótica da representatividade sáfica nas telenovelas da TV Globo
Authors: Hossmann Beatriz Glória , Grubits de Paula Pessôa Luís Alexandre , Nunes Pereira Severino Joaquim
Published: January 2025

O artigo em questão visa analisar, através da semiótica discursiva da linha francesa, os significados associados às mulheres sáficas nas telenovelas Torre de Babel (1998), Em família (2014) e Um lugar ao sol (2021), da TV Globo, visando compreender se houve uma transformação da representatividade destas, longitudinalmente. Sendo assim, através do diálogo com a teoria queer, torna-se possível perceber e analisar as vivências das personagens Leila e Rafaela, Clara e Marina e Ilana e Gabriela, ao longo de suas trajetórias nas respectivas tramas, entendendo se, para além da simples representação, existe uma visibilidade mais completa e naturalizada dessas personagens. Com isso, chega-se à conclusão de que, apesar de ser possível notar uma representatividade se constituindo, ainda existem questões que podem ser modificadas para que se obtenha uma maior naturalização social e pluralidade lésbica e bissexual em comparação com personagens que seguem um percurso heteronormativo no contexto dos produtos midiáticos estudados. Isso porque as trajetórias destas mulheres permanecem girando em torno das categorias profundas de aceitação e censura, além de todas elas corresponderem a um padrão hegemônico. Isto é, branco, magro, cisgênero, performático de feminilidade e de alta classe social, sendo estes corpos, por isso, completamente consumíveis e desejáveis dentro de uma sociedade normativa.