bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure S2 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Authors: Pal Sumanta K. , Tran Ben , Haanen John B.A.G. , Hurwitz Michael E. , Sacher Adrian , Tannir Nizar M. , Budde Lihua E. , Harrison Simon J. , Klobuch Sebastian , Patel Sagar S. , Meza Luis , Dequeant Mary-Lee , Ma Anna , He Qiuling Ally , Williams Leah M. , Keegan Alissa , Gurary Ellen B. , Dar Henia , Karnik Sushant , Guo Changan , Heath Heidi , Yuen Rachel R. , Morrow Phuong K. , Agarwal Neeraj , Srour Samer A.
Published: July 2024

Cytokine secretion during CAR T-cell activation upon coculture with CD70+ RCC cells
Supplementary Figure S6 from Randomized Placebo-Controlled, Biomarker-Stratified Phase Ib Microbiome Modulation in Melanoma: Impact of Antibiotic Preconditioning on Microbiome and Immunity
Authors: Glitza Isabella C. , Seo Yongwoo David , Spencer Christine N. , Wortman Jennifer R. , Burton Elizabeth M. , Alayli Farah A. , Loo Christopher P. , Gautam Shikha , Damania Ashish , Densmore Julie , Fairchild Justin , Cabanski Christopher R. , Wong Matthew C. , Peterson Christine B. , Weiner Brian , Hicks Nathan , Aunins John , McChalicher Christopher , Walsh Emily , Tetzlaff Michael T. , Hamid Omid , Ott Patrick A. , Boland Genevieve M. , Sullivan Ryan J. , Grossmann Kenneth F. , Ajami Nadim J. , LaVallee Theresa , Henn Matthew R. , Tawbi Hussein A. , Wargo Jennifer A.
Published: July 2024

Spore former family relative abundance over time
Supplementary Figure S3 from Randomized Placebo-Controlled, Biomarker-Stratified Phase Ib Microbiome Modulation in Melanoma: Impact of Antibiotic Preconditioning on Microbiome and Immunity
Authors: Glitza Isabella C. , Seo Yongwoo David , Spencer Christine N. , Wortman Jennifer R. , Burton Elizabeth M. , Alayli Farah A. , Loo Christopher P. , Gautam Shikha , Damania Ashish , Densmore Julie , Fairchild Justin , Cabanski Christopher R. , Wong Matthew C. , Peterson Christine B. , Weiner Brian , Hicks Nathan , Aunins John , McChalicher Christopher , Walsh Emily , Tetzlaff Michael T. , Hamid Omid , Ott Patrick A. , Boland Genevieve M. , Sullivan Ryan J. , Grossmann Kenneth F. , Ajami Nadim J. , LaVallee Theresa , Henn Matthew R. , Tawbi Hussein A. , Wargo Jennifer A.
Published: July 2024

Summary of clinical response by treatment arm and baseline Ruminococcaceae group
Supplementary Figure S15 from Randomized Placebo-Controlled, Biomarker-Stratified Phase Ib Microbiome Modulation in Melanoma: Impact of Antibiotic Preconditioning on Microbiome and Immunity
Authors: Glitza Isabella C. , Seo Yongwoo David , Spencer Christine N. , Wortman Jennifer R. , Burton Elizabeth M. , Alayli Farah A. , Loo Christopher P. , Gautam Shikha , Damania Ashish , Densmore Julie , Fairchild Justin , Cabanski Christopher R. , Wong Matthew C. , Peterson Christine B. , Weiner Brian , Hicks Nathan , Aunins John , McChalicher Christopher , Walsh Emily , Tetzlaff Michael T. , Hamid Omid , Ott Patrick A. , Boland Genevieve M. , Sullivan Ryan J. , Grossmann Kenneth F. , Ajami Nadim J. , LaVallee Theresa , Henn Matthew R. , Tawbi Hussein A. , Wargo Jennifer A.
Published: July 2024

Stool metabolomics principal component analysis
Supplementary Figure S13 from Randomized Placebo-Controlled, Biomarker-Stratified Phase Ib Microbiome Modulation in Melanoma: Impact of Antibiotic Preconditioning on Microbiome and Immunity
Authors: Glitza Isabella C. , Seo Yongwoo David , Spencer Christine N. , Wortman Jennifer R. , Burton Elizabeth M. , Alayli Farah A. , Loo Christopher P. , Gautam Shikha , Damania Ashish , Densmore Julie , Fairchild Justin , Cabanski Christopher R. , Wong Matthew C. , Peterson Christine B. , Weiner Brian , Hicks Nathan , Aunins John , McChalicher Christopher , Walsh Emily , Tetzlaff Michael T. , Hamid Omid , Ott Patrick A. , Boland Genevieve M. , Sullivan Ryan J. , Grossmann Kenneth F. , Ajami Nadim J. , LaVallee Theresa , Henn Matthew R. , Tawbi Hussein A. , Wargo Jennifer A.
Published: July 2024

Assessment of gut microbiome networks by treatment arm and across timepoints
Supplementary Figure S11 from Randomized Placebo-Controlled, Biomarker-Stratified Phase Ib Microbiome Modulation in Melanoma: Impact of Antibiotic Preconditioning on Microbiome and Immunity
Authors: Glitza Isabella C. , Seo Yongwoo David , Spencer Christine N. , Wortman Jennifer R. , Burton Elizabeth M. , Alayli Farah A. , Loo Christopher P. , Gautam Shikha , Damania Ashish , Densmore Julie , Fairchild Justin , Cabanski Christopher R. , Wong Matthew C. , Peterson Christine B. , Weiner Brian , Hicks Nathan , Aunins John , McChalicher Christopher , Walsh Emily , Tetzlaff Michael T. , Hamid Omid , Ott Patrick A. , Boland Genevieve M. , Sullivan Ryan J. , Grossmann Kenneth F. , Ajami Nadim J. , LaVallee Theresa , Henn Matthew R. , Tawbi Hussein A. , Wargo Jennifer A.
Published: July 2024

Comparison of baseline microbiome features by study arm.
Supplementary Figure S10 from Randomized Placebo-Controlled, Biomarker-Stratified Phase Ib Microbiome Modulation in Melanoma: Impact of Antibiotic Preconditioning on Microbiome and Immunity
Authors: Glitza Isabella C. , Seo Yongwoo David , Spencer Christine N. , Wortman Jennifer R. , Burton Elizabeth M. , Alayli Farah A. , Loo Christopher P. , Gautam Shikha , Damania Ashish , Densmore Julie , Fairchild Justin , Cabanski Christopher R. , Wong Matthew C. , Peterson Christine B. , Weiner Brian , Hicks Nathan , Aunins John , McChalicher Christopher , Walsh Emily , Tetzlaff Michael T. , Hamid Omid , Ott Patrick A. , Boland Genevieve M. , Sullivan Ryan J. , Grossmann Kenneth F. , Ajami Nadim J. , LaVallee Theresa , Henn Matthew R. , Tawbi Hussein A. , Wargo Jennifer A.
Published: July 2024

Beta diversity changes over time
Supplementary Table 1 from The Pan-RAF–MEK Nondegrading Molecular Glue NST-628 Is a Potent and Brain-Penetrant Inhibitor of the RAS–MAPK Pathway with Activity across Diverse RAS- and RAF-Driven Cancers
Authors: Ryan Meagan B. , Quade Bradley , Schenk Natasha , Fang Zhong , Zingg Marshall , Cohen Steven E. , Swalm Brooke M. , Li Chun , Özen Ayşegül , Ye Chaoyang , Ritorto Maria Stella , Huang Xin , Dar Arvin C. , Han Yongxin , Hoeflich Klaus P. , Hale Michael , Hagel Margit
Published: July 2024

KINOMESCAN data
Figure 2 from Inhibition of Notch4 Using Novel Neutralizing Antibodies Reduces Tumor Growth in Murine Cancer Models by Targeting the Tumor Endothelium
Authors: Eng Jason W.-L. , Kato Yu , Adachi Yusuke , Swaminathan Bhairavi , Naiche L.A. , Vadakath Rahul , Sakamoto Yoshimasa , Nakazawa Youya , Tachino Sho , Ito Ken , Abe Takanori , Minoshima Yukinori , Hoshino-Negishi Kana , Ogasawara Hideaki , Kawakatsu Tomomi , Nishimura Miyuki , Katayama Masahiko , Shimizu Masashi , Tahara Kazuhiro , Sato Toshitaka , Suzuki Katsuhisa , Agarwala Kishan , Iwata Masao , Nomoto Kenichi , Ozawa Yoichi , Imai Toshio , Funahashi Yasuhiro , Matsui Junji , Kitajewski Jan
Published: July 2024

Treatment of human tumor xenografts with 6-3-A6 delays growth of tumors which express endothelial Notch4. A, IF staining of Notch4 (red) and CD31+ tumor vessels (green) in human tumor xenografts. Arrowheads indicate Notch4-expressing vessels (Scale bar = 200 μm). B and C, Tumor growth curves of subcutaneously implanted tumors from the indicated cell lines. B, MDA-MB-231 xenografts treated intravenously with 6-3-A6 (n = 5). C, Calu-6 human NSCLC xenograft tumors treated intravenously with 6-3-A6. All treatments started 12 hours after tumor implantation. Statistical analysis performed with two-way ANOVA for tumor growth curves, plotted as average ± SEM; *, P < 0.05.
Data from Inhibition of Notch4 Using Novel Neutralizing Antibodies Reduces Tumor Growth in Murine Cancer Models by Targeting the Tumor Endothelium
Authors: Eng Jason W.-L. , Kato Yu , Adachi Yusuke , Swaminathan Bhairavi , Naiche L.A. , Vadakath Rahul , Sakamoto Yoshimasa , Nakazawa Youya , Tachino Sho , Ito Ken , Abe Takanori , Minoshima Yukinori , Hoshino-Negishi Kana , Ogasawara Hideaki , Kawakatsu Tomomi , Nishimura Miyuki , Katayama Masahiko , Shimizu Masashi , Tahara Kazuhiro , Sato Toshitaka , Suzuki Katsuhisa , Agarwala Kishan , Iwata Masao , Nomoto Kenichi , Ozawa Yoichi , Imai Toshio , Funahashi Yasuhiro , Matsui Junji , Kitajewski Jan
Published: July 2024

Abstract
Endothelial Notch signaling is critical for tumor angiogenesis. Notch1 blockade can interfere with tumor vessel function but causes tissue hypoxia and gastrointestinal toxicity. Notch4 is primarily expressed in endothelial cells, where it may promote angiogenesis; however, effective therapeutic targeting of Notch4 has not been successful. We developed highly specific Notch4-blocking antibodies, 6-3-A6 and humanized E7011, allowing therapeutic targeting of Notch4 to be assessed in tumor models. Notch4 was expressed in tumor endothelial cells in multiple cancer models, and endothelial expression was associated with response to E7011/6-3-A6. Anti-Notch4 treatment significantly delayed tumor growth in mouse models of breast, skin, and lung cancers. Enhanced tumor inhibition occurred when anti-Notch4 treatment was used in combination with chemotherapeutics. Endothelial transcriptomic analysis of murine breast tumors treated with 6-3-A6 identified significant changes in pathways of vascular function but caused only modest change in canonical Notch signaling. Analysis of early and late treatment timepoints revealed significant differences in vessel area and perfusion in response to anti-Notch4 treatment. We conclude that targeting Notch4 improves tumor growth control through endothelial intrinsic mechanisms.
Significance:
A first-in-class anti-Notch4 agent, E7011, demonstrates strong antitumor effects in murine tumor models including breast carcinoma. Endothelial Notch4 blockade reduces perfusion and vessel area.
Accelerated Linear Growth during Erdafitinib Treatment: An FGFR-Related, but Growth Factor and Sex Steroid-Independent Mechanism?
Authors: Raimann Adalbert , Stepien Natalia , Azizi Amedeo A. , Hartmann Gabriele , Gojo Johannes
Published: July 2024

Introduction: Growth acceleration during postnatal growth only occurs during puberty as a physiological event and during catch-up growth mediated by growth-promoting therapies in growth disorders. Here we report on novel observations of skeletal symptoms during treatment with erdafitinib, a tyrosine kinase inhibitor (TKI) prescribed on the basis of a compassionate-use program. Methods: Analysis of anthropometric, biochemical, clinical, and radiographic data of patients with CNS tumors who revealed an unanticipated growth spurt with initiation of therapy with erdafitinib was performed retrospectively. Results: Linear growth acceleration was independent of sex steroids and IGF1 levels, which is especially remarkable in the context of heavily pretreated pediatric neuro-oncology patients with severe growth impairment before initiation of therapy. Growth acceleration was accompanied by a distinct widening of the growth plate and enhanced metaphyseal mineralization shortly after the start of TKI therapy. Conclusions: While targeted therapies including TKIs have become an essential part of adult cancer treatment, applications in children are still limited. Off-target effects specific to the pediatric population have been observed in various organ systems; however, knowledge about the effect of TKIs on the growing skeleton is scarce. Treatment with erdafitinib inhibits FGFR3-mediated effects and thus represents a very logical hypothetical framework of growth factor and sex steroid-independent growth acceleration.
Living to Serve: The Cupbearer’s Dream (Gen 40)
Authors: Grossman Jonathan
Published: July 2024

At first glance, it seems that the cupbearer’s dream (Gen 40) does not require a special symbolic interpretation. Aside from the three branches symbolizing three days, Joseph interpreted the dream literally: the cupbearer will be restored to his esteemed position and serve wine to the king. Nonetheless, this article raises the possibility that there is a symbolic meaning in the vine’s blossoming (40:10), which Joseph interpreted with the words: “Pharaoh will lift up your head” (40:13). According to this suggestion, the cupbearer’s dream and the baker’s dream should be explained in similar ways: both dreams are symbolic dreams in which the official is represented by the produce he is responsible for.
Masoretic Forensics and Scribal Fingerprints
Authors: Phillips Kim
Published: July 2024

In recent years three bilingual Hebrew-Judaeo-Arabic Torah manuscript fragments have been tentatively identified as the work of the scribe Samuel b. Jacob (best-known for his production of the so-called Leningrad Codex): CUL T-S Ar.1a.2+; RNL EVR II A 640; Oxf. MS heb. f. 108/3. These identifications were made on the basis of script similarity alone. This study, premised on the work of the great Hebrew codicologist Malachi Beit-Arié, demonstrates that all three of these manuscripts have been mis-identified. Thereby, the study affirms Beit-Arié’s claim that, at least in the case of early Eastern Hebrew Bible codices, scribal identifications should not be made on the basis of script alone, but on a raft of textual and paratextual scribal features that remain demonstrably stable across a given scribe’s oeuvre.
Me, My Sin, and I
Authors: Kim World
Published: July 2024

This article seeks to situate Paul’s Sin in Rom 7 within the context of Second Temple exegetical practices concerning sources of evil. Drawing on the work of Carol Newsom and Ishay Rosen-Zvi, the author argues that Paul’s discourse on Sin in Rom 7 marks an instance of self-alienation in which the “I” distances itself from Sin which is objectified as an evil power within the self. While Sin is certainly distinguishable from the self, the author here contends that Sin is not ontologically distinct from the self. Accordingly, Sin is not an external, cosmic power but, rather, envisioned as an internal, evil entity that is inherent to and arises from the self.
Contrasting Human Speech in Hebrews 12–13
Authors: Stevens Daniel
Published: July 2024

This article will analyze an under-studied aspect of the Epistle to the Hebrews: human speech. In so doing, the author will show how the letter-writer creates an implicit comparison between the audience of the epistle and Moses, placing the audience in a position more privileged than Moses himself. The argument will proceed by justifying the scope of the material to be considered, Heb 12–13, then examining the few but significant instances of human discourse in the letter. The author will argue that the letter-writer’s use of explicitly human discourse serves the epistle’s overall argumentative purpose of encouraging the audience to continued adherence to Jesus through a comparison of the Mosaic and new covenants, particularly in reference to the events immediately after the exodus from Egypt. Then the author will conclude with reflections on the rhetorical use of human discourse and the potential implications for the structure and literary unity of Hebrews.
Exploring Oman’s International Tourism Determinants in a Gravity Modelling Framework
Authors: Gani Azmat , Al-Kharusi Sami
Published: July 2024

This research investigates Oman’s international tourism predictors within a coherent gravity modelling framework. International visitor arrival data for 2007 to 2015 involving Oman’s forty-eight main visitor origin countries are incorporated in the balanced panel estimation empirical phase that tests several gravity model specifications. The estimation procedure includes standard gravity variables and controls for several hypothesized influences. The findings provide strong evidence that the economic sizes of visitor recipient and origin countries, the distance between Oman and visitor origin countries, humidity, quality of accommodation, and common religion are statistically significant predictors. Surprisingly, while relevant, Oman’s cultural attractions (museums, forts, and castles) and the extent of human freedom are statistically insignificant. These findings are unique as they focus on the importance of factors determining Oman’s tourism within a cohesive and inclusive modelling framework. Policymakers can target the abovementioned variables to facilitate investments and propel tourism.
Estranged Kinship: Empathy and Animal Desire in Merleau-Ponty
Authors: Rogers Chandler D.
Published: July 2024

Merleau-Ponty suggests in his Nature lectures that myth provides the best way into thinking the relation of strange kinship between humanity and animality. He goes on to refigure Husserl’s paradigm of the two hands touching to extend beyond merely human-to-human relations, invoking in the process the myth of Narcissus. By carefully examining Merleau-Ponty’s late refiguration of that paradigm, alongside the revised conception of narcissism that it helps him to develop, we find that while human-animal empathy is made possible by a ground of intercorporeal kinship, human-animal estrangement makes possible the emergence of an ethical relation to other animals, contingent upon the sublimation of animal desire. Holding human-animal kinship and estrangement in tension reveals a nascent ideal present implicitly in the early stages of childhood development: a vision of the possibility of interspecies harmony, rooted in the bodily reciprocity that drives the process of self-maturation.
Critical Religion Takes a Punch: Notes on a Scholarly Skirmish
Authors: Goldenberg Naomi
Published: July 2024

In this reply to the article “Can Critical Religion Play by Its Own Rules? Why There Must Be More Ways to Be ‘Critical’ in the Study of Religion” by Galen Watts and Sharday Mosurinjohn (2022), I take exception to the authors’ criticisms. I call attention to Watts’ and Mosurinjohn’s implication that critical religion enables racism, their imaginary construction of a methodological ‘school’ with rigid ‘rules,’ and their simplistic dismissal of Foucault’s approach to discourse analysis. I then suggest that the suspension of reified categories in Religious Studies opens up promising avenues for theory and research.
In Search of Rules for a Critical Study of Religion
Authors: Sheedy Matt
Published: July 2024

This article builds on critical engagements with a 2022 essay that appeared in the Journal of the American Academy of Religion. At the centre of this essay was a concern with the influence of ‘Critical Religion’ (CR) on the academic study of religion, including the idea that CR is crypto-normative, inconsistent when applying its critiques, is overly deconstructive, and is unable to address ethical claims. Taking issue with some of the arguments in this essay, this article aims to push the conversation in a different direction by asking, are their rules for a critical study of religion? If so, then what do various ‘critical’ camps share in common? Where do they differ, and what kind of work is being done to move beyond some of these impasses today?
She Shores
Authors: Roy Meghna , Singh Jyoti
Published: July 2024

This study delves into the lives of women from the Koli fishing community in Mumbai, aiming to illuminate their unique life experiences and the daily struggles that often remain hidden beneath their prosperous facade. It endeavours to examine their agency and adaptive strategies employed to navigate these challenges. The research was conducted in Pachubandar, Vasai, located in the western suburbs of Mumbai, which stands as one of the prominent Koli settlements in the city. Employing a qualitative research approach coupled with an exploratory research design, the study engaged ten participants, comprising seven Koli women and three key informants from the community. Additionally, an observational analysis of four retail and wholesale fish markets in Mumbai was conducted to gain insight into the working conditions of Koli fisherwomen.

This study adopts a gender-focused perspective to scrutinise the contextual vulnerabilities that shape the lives of Koli women. It underscores the paradox wherein, despite playing a pivotal role in sustaining both their families and the traditional fishing occupation, their contributions often go unnoticed. The Koli women face severe deprivation due to their limited access to property and decision-making authority. They find themselves entangled within traditional norms and patriarchal structures, which impede their access to essential assets and diverse livelihood resources. Although they significantly contribute to the fishery sector, their struggles, needs, and aspirations are frequently disregarded due to their lack of representation and involvement in decision-making bodies. The majority of these women work under precarious conditions, devoid of proper infrastructure, resources, and security. Furthermore, the evolving dynamics within the fishery sector, driven by rapid urbanisation and modernisation, have a profound impact on the lives and traditional livelihoods of Koli women. They now confront issues such as dwindling fish catches due to environmental degradation, heightened market competition, reduced livelihood spaces brought about by shifting urban and coastal landscapes, altered labour relations, and technological advancements. Consequently, they find themselves caught between the conflicting forces of tradition and modernity. The research also sheds light on the strategies devised by Koli women to resist and adapt to the uncertainties and challenges they encounter, ultimately safeguarding their livelihoods through self-organisation. The study emphasises the imperative to acknowledge their contributions as ‘visible work’ and advocates for the incorporation of gender considerations when formulating policies and development strategies within the fisheries sector.
Listening the Echoes of Silence
Authors: Mohammed Awol Ali
Published: July 2024

This scholarly article examines the intricate layers of social, economic, and political marginalisation experienced by the ‘Negede Weyto’ minority and elucidates its impacts on their psychological well-being. Employing a qualitative research approach, the study synthesised primary and secondary data sources. Primary data collection methods included in-depth interviews, informant interviews, and focus group discussions, complemented by meticulous analysis of relevant documents. The findings reveal that socially, the ‘Negede Weyto’ face marginalisation and restrictions in societal interactions, local associations, and religious events due to stereotyped and prejudiced perceptions. Economically, the minority group encounters challenges such as land eviction, limited opportunities, and exclusion from the job market, exacerbated by perceived educational and competence deficiencies. Politically, the ‘Negede Weytos’ are marginalised from local governance, with limited participation in elections and decision-making processes. Consequently, the ‘Negede Weyto’ minority experiences detrimental effects on their psychological well-being due to the cumulative impact of enduring marginalisation.
Reparation and Reconciliation
Authors: Meijers Erica
Published: July 2024

After several decades of relative silence in the Netherlands on the topic of church and racism, the Black Lives Matter Movement and the public debate on reparations for colonial enslavement have brought the issue back on the agenda of church and theology. Fuelled by the Programme to Combat Racism (PCR), previous ecumenical discussions on this topic in the 1970s provide a good starting point for reflection today.

This paper first provides some basic background on the PCR and then describes three theological positions in relation to reconciliation that shaped the discussions around racism. Based on these historical insights, the article summarizes the experiences and insights of the PCR in three major points, and discusses their relevance for today’s conversation on church, diaconia, and racism. The paper argues that commitment, the transfer of power, and the value of discomfort provide important theological and practical insights for today’s debate.
Misunderstanding Equality, Power, and Vulnerability: Elevating the Individual over Cohesion in Hierarchy as a Value
Authors: Rauchholz Elizabeth
Published: July 2024

This article explores dominant ideas of value at play in a critical incident experienced by international mission candidates on a team placement, in an Anglican community of the United Kingdom. The ethnographic analysis will compare different perspectives on how misunderstanding cultural values and social relations as theological obligations can lead to suffering. Thus, the study shows how qualitative differences in cultural values and social relations determine contrary ways of understanding theological conceptualizations of equality as a Christian idea in contact zones of international mission communities. The analysis challenges two Christian assumptions: firstly, that extending equal value to people before God is universally understood in the same way, and secondly, that individual well-being is inherently superior to ensuring social cohesion, exemplified by Korean hierarchy. Although people realize hierarchy and individualism the world over, the nuances of meaning dominating their relations to other values determine why and how people experience suffering.
Seeing Wrongness
Authors: Toribio Josefa
Published: July 2024

This paper examines the plausibility of an attention-based version of moral perceptualism (amp). According to amp, our perception of moral properties is characterized by perceptual attentional patterns that reflect a sensitivity to morally salient features. First, I argue that the explanation for the empirical evidence offered to support amp primarily hinges on cognitive processes rather than perceptual ones. Second, while I acknowledge the critical importance of attention in recognizing moral properties, I contend that we must expand amp’s explanatory scope to address the question of what drives this attention. I propose an account of our (in)sensitivity to wrongness that builds on amp’s core statement. In this account, the notion of salience structure of information, defined by the varying accessibility of both perceptual and cognitive representations, plays a central explanatory role.
Nonviolent Knowledge(s) and Unarmed Civilian Protection
Authors: Ridden Louise
Published: July 2024

In its claim to take the human, and in particular the civilian, as the referent object of security, human security seeks to build not only physical but ontological security for those who live and work in conflict-affected communities; those who shape conflict and are shaped by it. Unarmed civilian protection (ucp), a method of civilian-to-civilian and civilian self-protection, is led by the civilians who make up conflict-affected communities. Rather than ‘including’ local actors in their protection or seeking to extract information about conflict from them, ucp is a practice in which local and international actors work together to co-create and build spaces of protection. This protection is based on conflict knowledge which enables nonviolent protection methods to be practiced effectively. This knowledge comes not from armed actors nor state delegates, but rather from and with conflict-affected communities. Embracing civilian experiential knowledge of armed and violent conflict, ucp instrumentalises civilians, their knowledge(s) of and relationships to armed conflict in the creation of protection networks. Taking ucp as a case study of nonviolent protection, and ucp practitioners as conflict knowledge producers, this article argues that civilian experiential knowledge of armed conflict is essential to the pursuit of civilian protection. Rather than being a prescriptive set of aims, the human security agenda must take seriously the experiences of civilians affected by conflict, centring their experiential knowledge(s) and agency in order to move beyond the unintentional yet harmful (re)production of binary security logics.
The University of Zimbabwe Department of English’s Dambudzo Marechera (2013–2018)
Authors: Fingson Kundai Watson
Published: July 2024

In this article, I discuss the personal (autobiographical), literary and political relationship between Dambudzo Marechera’s texts, the University of Zimbabwe’s then Department of English and my own development as an early career scholar. This relationship went beyond academia. Through a reflection on the various pedagogical approaches used by the department’s lecturing staff, I arrive at Marechera’s lasting literary legacy vis a vis the implications of ideological readings of literature in Zimbabwe. Marechera’s The House of Hunger, specifically, reveals the ideologies that are constantly employed in the reading of Zimbabwean Literature, which in turn, reveals the patriotism litmus test to which every aspect of Zimbabwean life is subject. The approaches impeded and facilitated critical readings to various degrees. I will argue that Marechera’s text’s stylistic and thematic concerns which traversed the literary, political, and autobiographical terrains complicated some of the readings and invited the microscopic scrutiny to which both the author and his work were subjected. Essentially, I discuss the identity and processes of identity making that revealed themselves in the reading of The House of Hunger and how all of these have impacted my own development as a young academic.
Meeting Dambudzo at Oxford
Authors: Chikafa-Chipiro Rosemary
Published: July 2024

This paper is a narrative of my personal (physical and spiritual) encounter with Dambudzo Marechera during my research visit at Oxford. Marechera was a prolific Zimbabwean writer, poet and playwright whose memory is entrenched in the Zimbabwean imagination because of his artistic prowess and personal-political exploits. He was expelled from the University of Oxford in 1976 and died in Zimbabwe on 18 August 1987. My encounter with Dambudzo is punctuated by my quest to understand what it was like for him as a black Zimbabwean in exile studying at the prestigious institution and having to maneuver his racial and cultural difference. The narrative weaves my personal experiences at Oxford, of British museums and meeting with his biographer into perceptions of Dambudzo Marechera’s archive at Oxford to bring a new understanding—including a psychological and/or clinical review—of Marechera’s memory from a black Zimbabwean perspective and hopefully perpetuate his archive.
Lacticaseibacillus rhamnosus LRa05 alleviated liver injury in mice with alcoholic fatty liver disease by improving intestinal permeability and balancing gut microbiota
Authors: Gu J. , Chen Y. , Wang J. , Gao Y. , Gai Z. , Zhao Y. , Xu F.
Published: July 2024

This study investigated the effect of Lacticaseibacillus rhamnosus LRa05 on alcoholic fatty liver disease (ALD) and its mechanism for liver protection. Mice were randomly divided into three groups: a control (CLT) group, an ALD group, and a LRa05 intervention group. The ALD mouse model was established by Lieber-DeCarli chronic alcohol feeding. Tissues staining, enzyme-linked immunosorbent assay (ELISA) was performed to detect changes in histopathology and inflammatory cytokines, respectively. Moreover, intestinal permeability was evaluated by the level of dextran-fluorescein isothiocyanate (Dx-FITC) in serum and tight junction protein in the colon. Changes in the composition of the gut microbiota were assessed by 16S rRNA sequencing. Alcohol consumption induced liver damage in mice with significantly increased levels of triglycerides (TG), aspartate aminotransferase (AST), alanine transaminase (ALT), and inflammatory cytokines. Moreover, alcohol further induced the increase of intestinal permeability and disruption of gut microbiota in mice, with an increase in the relative abundance of potentially pathogenic bacteria Enterococcus, Parabacteroides, and Alistipes. LRa05 intervention significantly attenuated alcohol-induced liver injury by reducing the contents of TG, ALT, and AST, and suppressing the inflammatory responses. Meanwhile, by stimulating the expression of ZO-1, Occludin, and Claudin in the colon tissue, LRa05 additionally strengthened the intestine barrier function. Furthermore, gut microbiota analysis suggested that LRa05 partially ameliorated gut microbiota disorders in ALD mice and up-regulated the abundance of Desulfovibrio and Akkermansia, which were negatively correlated with the indicators of ALD progression. The reconstructive effects of LRa05 on the gut microbiota might be related to the efficacy of LRa05 in improving gut permeability and further protecting against ALD.
Beneficial effect of GABA-producing Lactiplantibacillus strain LPB145 isolated from cheese starters evaluated in anxiety- and depression-like behaviours in rats
Authors: Lozano J. , Fabius S. , Fernández-Ciganda S. , Urbanavicius J. , Piccini C. , Scorza C. , Zunino P.
Published: July 2024

In a previous study, we reported the in vitro potential probiotic and gamma-aminobutyric acid (GABA) production, of several strains from a collection of Lactiplantibacillus (Lpb) strains within the community of natural whey starters from the artisanal cheese industry. GABA is a non-protein amino acid widely distributed in nature and produced in animals, plants, and microorganisms. However, the best known role of GABA is its function as the major inhibitory neurotransmitter of the central nervous system. Preclinical and clinical evidence suggests that the GABAergic system has a relevant role in mental health disorders, such as anxiety and major depression. The modulation of the GABAergic system has been suggested as a potential strategy for treatment, one such mechanism of modulation is the influence of the microbiota-gut-brain axis through probiotic treatments. The present study was designed to investigate the in vivo probiotic potential of LPB145, a Lactiplantibacillus strain previously characterised as a GABA-producing potentially probiotic strain. Therefore, we evaluated the behavioural effects of chronic oral administration of LPB145 on rats’ anxiety- and depression-like behaviours, using the elevated plus maze, open field, and the forced swimming test. The impact of LPB145 strain treatment on the gut microbiota structure and diversity was assessed to discern a possible mechanism of action of the LPB145 treatment through the microbiota-gut-brain axis. Our results showed that LPB145 administration induced an antidepressive-like behaviour without changes in locomotor activity. In contrast, the treatment did not modify the experimental anxiety. The structure and diversity of the intestinal microbiota remained unaffected by the treatment when compared to the control. However, specific clades that could be implicated in the behavioural changes did show differences in their relative abundance. These findings provide evidence regarding the potential of probiotic strains isolated from alimentary sources, to modulate the microbiota-gut-brain axis and positively impact mental health.
Complicity and Cold War Politics: The Long Shadow of Unit 731 in Sino-U.S. Relations
Authors: Matson Emily M.
Published: July 2024

The horrific human experimentation Ishii Shirō and his colleagues conducted at Unit 731 is a dark chapter in China’s War of Resistance against Japan. Less well known, however, is the U.S. role in covering up this atrocity with a postwar decision to grant immunity to the perpetrators in exchange for the research data they possessed. Moreover, there exist strong allegations to this day in China that the United States subsequently conducted bacteriological warfare against Chinese and North Korean civilians in the Korean War. This article examines how memories of this “victor’s justice” remain a strong component of Chinese patriotic education today. It argues that China’s “century of humiliation,” which focuses on Chinese victimization at the hands of foreign imperialists, did not end in 1949 with the formation of the People’s Republic of China, but rather the Chinese Communist Party employs it today to portray Chinese victimization at the hands of U.S. imperialism through at least the end of the Korean War in July 1953. Furthermore, this article suggests that understanding Chinese public memory of Unit 731 is extremely relevant to understanding contemporary Sino-American relations because these memories help shape public perception of the United States for ordinary Chinese.
The ‘Reischauer Offensive’: A Scholar-Diplomat’s Challenge to Japan’s Leftist Intellectuals, 1961–1966
Authors: Yoshii Midori
Published: July 2024

The article discusses Edwin O. Reischauer’s role in the scholarly debates on the modern history of Japan during his ambassadorship from 1961 to 1966. It challenges Takeshi Matsuda’s recent interpretation in his Soft Power, and Its Perils: U.S. Cultural Policy in Early Postwar Japan and Permanent Dependency that the “Reischauer Offensive” aimed to make Japan feel subservient, creating “a psychology of dependence.” The article argues instead that Reischauer’s efforts for “equal partnership” and his scholarly challenge to Marxists' interpretation brought a culture of open debate in Japan.
Contact-Induced Change in the Jewish Neo-Aramaic Dialects
Authors: Khan Geoffrey
Published: July 2024

In this article, I present an introductory overview of the Jewish Neo-Aramaic dialects, followed by a study of various aspects of contact-induced change that are exhibited by these dialects. Neo-Aramaic dialects were also spoken by Christian communities in the same region. The Jewish and Christian dialects differ from one another, even where the two communities lived in the same geographical area. I show that contact-induced change was generally more advanced in Jewish NENA dialects than in neighboring Christian dialects. I also demonstrate that a study of contact-induced changes provides evidence of the migration history of the communities. I present two case studies of differing degrees of convergence with contact languages and evidence of different migration patterns. These are (i) the Jewish and Christian NENA dialects of Urmi (northwestern Iran) and (ii) the Jewish and Christian NENA dialects of Sanandaj (western Iran).
“This Is Called Ḥaliq”
Authors: Sienna Noam
Published: July 2024

Descriptions of the Passover evening service in Gaonic writings of the late ninth and early tenth centuries include the word ḥaliq as an alternative term for ḥaroset, a sweet and sour dipping sauce made from fruit and nuts. Through a diachronic view of ḥaroset in both the Greco-Roman context of the rabbinic Passover meal and the ʿAbbasid context of Gaonic Judeo-Arabic writing, I argue that the etymology of ḥaliq should be derived ultimately from the Latin allec, referring to a fermented fish sauce that was an essential ingredient of the dipping sauces from which ḥaroset evolved. I conclude with a survey of how ḥaliq (and words derived from it) was maintained as a term for ḥaroset in Jewish languages around the world from the Middle Ages until the present day.
The Letters of the Geonim as a Source of Epistolary Linguistic Forms in Modern Hebrew
Authors: Stern Ruth
Published: July 2024

The writing formulas in official letters in Modern Hebrew are often identical or similar to the formulas revealed in the Geonic letters. This article presents these similar formulas with two purposes in mind: 1) to illustrate the significance of the Interim Period for the formation of Modern Hebrew; 2) to show that the continuity of the use of the Hebrew language throughout history was a major factor that allowed the revival of Modern Hebrew.
The Centrality of the Workplace and Class Consciousness in the US South: The New Orleans Community Studies
Authors: Melcher Cody R. , van der Naald Joseph
Published: July 2024

The popular and scholarly imagination considers Americans—especially those from the US South—to be averse to working-class politics. The South, in particular, is regarded as having especially low levels of class consciousness, hopelessly mired in racist or racialized ideologies which effectively eliminate the possibility of working-class solidarity. This article problematizes these conclusions by presenting the results of a series of studies conducted in New Orleans, Louisiana. Interviews with activists and community leaders, as well as two representative surveys of the city find that New Orleanians are remarkably class conscious, and almost universally regard the workplace as the central social system for determining their overall well-being. These findings are contextualized in Louisiana’s oft-ignored labor history, and contrasted with the currently en vogue “white working class” literature.
Le maître et la vassale
Authors: Vuillerod Jean-Baptiste
Published: July 2024

Cet article se propose de revenir sur l’appropriation, par Simone de Beauvoir, de la dialectique hégélienne du maître et de l’esclave. Il montre que, dans Le Deuxième Sexe, les femmes ne sont pas des esclaves, mais des vassales. Ce déplacement du rapport d’esclavage à une relation de vassalité permet à Beauvoir de préserver la liberté ambiguë des femmes : ce qui les rend certes complices de leur domination, mais maintient également chez elles la potentialité de l’émancipation.
The Theme and the Form: Three Querelles in al-Ǧāḥiẓ’s Dispute over Girls and Boys
Authors: Magliozzi Aurora
Published: July 2024

The literary dispute over the respective merits of girls and boys as objects of desire, well known in ancient traditions, appears in Arabic literature from the 9th century onwards. Al-Ǧāḥiẓ’s Mufāḫarat al-ǧawārī wa-l-ġilmān (Boasting Match over Maids and Youths) is, at the earliest extant, the first text in prose dealing with this issue, and it opened the floor for several later works.

The author addresses this theme by means of the literary genre of the debate, in Arabic mufāḫara, in which the lover of girls (ṣāḥib al-ǧawārī) and the lover of boys (ṣāḥib al-ġilmān) present their arguments. In addition to the main debate, two other disputes occur in the text: one between the ancient poets (al-qudamāʾ) and the moderns (al-muḥdaṯūn), and the other between Basra and Kufa. The former is one of the main debates of the Abbasid literary criticism, and the latter is another literary topos in the early Abbasid period. We could even understand the Mufāḫara, therefore, as structured through not one but three mufāḫarāt.

The aim of this contribution is to highlight the importance of the “form” of the text – namely the literary dispute – by analyzing how the three debates interact within the text. I therefore argue that, although the theme addressed in the essay remains of a great interest today, the aim of the text is not only to discuss erotic practices but also to teach the reader a lesson of dialectic.
Historiographical Models for the Study of Anne Conway’s Principia
Authors: Rodríguez Teresa
Published: July 2024

In this article I analyze the different historiographical models that have contributed to the ‘interpretative heritage’ of Anne Conway. I argue that, due to the current state of scholarship on the history of women philosophers, the main mission of this scholarship is to increase the interpretative heritage of their works in general and of Anne Conway in particular. For this purpose, it is necessary to apply a pluralistic perspective regarding models. A pluralist perspective would argue that there are different historiographical models that apply to the study of the text and that each model, even the failed ones, increases the interpretative heritage. In this sense, I identify six main models used in the study of Conway’s Principia and propose that the sixth, the contextual/eclectic model, is more fundamental for the study of Anne Conway because it assists us in laying the foundations for other more restricted or specialized models.
A Worldly Kingdom of Heaven in T. C. Chao’s Early Theology
Authors: Zha Changping
Published: July 2024

This paper discusses the conception of an ideal world present in T.C. Chao’s (Tsu Chen Chao) (1888–1979) early theological works, based mainly on the text Jesus’ Philosophy of Life (or, A New Interpretation of the Sermon on the Mount, written in late 1925). It concludes by pointing out that Chao’s view of a kingdom of heaven that ultimately eradicates the otherworld and does not transcend this world unconsciously echoes the Anti-Christian Μovement within Chinese churches during the same period. This is, indeed, a tragedy in the development of T. C. Chao’s personal theological thought in the 1920s and 1930s.
الانتقال اللاهوتيّ في دوائر المستعربين الفكريّة في القرن الثاني عشر وعلاقاته المحتملة بالخلافات اللاتينيّة في القرن التاسع
Authors: مونفيرير-سالا خوان بيدرو
Published: July 2024

المستخلص

‫تُتيح لنا الأعمال التي وصلتنا التعرّفَ إلى عالم المفكّرين المستعربين في القرنين الحادي عشر والثاني عشر، فضلًا عن علاقاتهم المحتملة مع أوساط أخرى في شبه الجزيرة الأيبيريّة والشرق المسيحيّ. ومع ذلك، لا نعرف اليوم إلّا القليل عن العلاقات بين المفكّرين المستعربين في القرون الثلاثة الأولى، أي من القرن الثامن وحتّى العاشر. ومن النصوص التي وصلتنا من القرن التاسع، الرسالة إلى أهل غلاطية، وترجمة سفر المزامير على يد حفص بن البرّ القوطيّ القرطبيّ. واستنادًا إلى هذين النصّين وغيرهما، يبدو أنّ الحياة الأدبيّة التي طوَّرها مفكّرون لاتينيّون-عرب ثنائيّو اللغة قد ازدهرت أبكر ممّا يتوقّعه الدارسون. يحاجج هذا المقال أنّ المفكّرين المسيحيّين المعرّبين كانوا مدينين لهذا الإرث اللاتينيّ ومؤلّفيه وأفكاره، ووظّفوه كثيرًا في إنتاجهم باللغة العربيّة مكيّفين أفكاره وتأثيراته، إلى جانب مصادر أخرى متنوّعة.‬
An Imaginary Predicament
Authors: Elder-Vass Dave
Published: July 2024

This review article discusses key arguments from Social Imaginary and the Metaphysical Discourse by Christoforos Bouzanis, defending critical realism against criticisms made in the book.
The Ports of the Eastern Red Sea Before Islam: A Historical and Cultural Study
Authors: Ghazi Shuʿayb Marwan bin
Published: July 2024

This study focuses on tracing the history of the ports in the eastern Red Sea since ancient times. It documents the history of the most important of these ports and the challenges in determining their locations. It also traces their impact on the Arabs’ dominance over the Red Sea during certain historical periods, and their role in civilizational contact with the northeastern region of the African continent. The study also shows the evolution of Arab maritime capabilities, from the use of leather ships to purchasing ready-made ships, until they reached the point of manufacturing their own ships. It highlights some aspects of civilizational and cultural communication between the western region of the Arabian Peninsula and the northeastern region of Africa.
A phyllocladiferous new species of Phyllanthus (Phyllanthaceae) from Minas Gerais, Brazil
Authors: ORLANDINI PRISCILA , CORDEIRO INÊS , LOMBARDI JULIO ANTONIO , ZAVATIN DANILO ALVARENGA , SOUZA VINICIUS CASTRO
Published: July 2024

We describe a new phyllocladiferous species of Phyllanthus, which is endemic to the Minas Gerais state, Brazil, and is found within the Serra Nova State Park. This new species has cylindrical phylloclades, like those of P. choretroides, another endemic species in Minas Gerais, and P. goianensis and P. chapadensis, both exclusive to the state of Goiás. However, we present distinct characteristics that enable a clear differentiation between these species, related to the aspect of ramification of the phylloclades, morphology of stipules and sepals and characteristics of the extrastaminal disk. Additionally, we provide illustrations, photographs, distribution map, conservation status data and taxonomic comments of the new species.
Laurence A. Mound 90 years: A collaborative life that laid the foundation of modern thrips studies
Authors: LIMA ÉLISON FABRÍCIO B. , TREE DESLEY J. , WELLS ALICE , CAVALLERI ADRIANO
Published: July 2024

In honour of Laurence Mound's 90th birthday, this special issue of Zootaxa serves as a tribute to his enduring legacy in entomology and Thysanoptera research. Mound's journey in the field has been marked by numerous discoveries, unwavering dedication, and invaluable collaborations that have profoundly influenced the study of Thysanoptera around the world. We here emphasise his lifelong commitment to the study of these minute insects and this provides an opportunity for researchers worldwide to share their insights and experiences, highlighting the impact Mound has had on their scientific pursuits. Through an interview exploring Mound's career choices, this paper also unravels the intricate paths he traversed and the collaborations that proved to be the driving force behind his Thysanoptera research to the age of 90.