bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of sunflower breeding material for productivity in the Black-Earth region conditions
Authors: Иванова О.М. , Ветрова С.В. , Ерофеев С.А.
Published: August 2024

Представлены результаты научных исследований за период 2021–2023 гг., проведенных на черноземах типичных Тамбовской области с учетом изменения агроклиматических условий региона. За годы проведения научно-исследовательских работ по селекции подсолнечника в питомнике конкурсного сортоиспытания (КСИ) было выделено 9 перспективных образцов подсолнечника селекции Института. Урожайность линий подсолнечника за три года изучения в КСИ составляла от 1,55 до 2,19 т/га. Наивысшая прибавка урожайности относительно контроля сорт Спартак была получена у линии 436 и составила 0,12 т/га.

The results of scientific research for the period 2021–2023, conducted on typical black soils of the Tambov region taking into account changes in agroclimatic conditions of the region, are presented. During the years of research work on sunflower breeding in the nursery of competitive variety testing (CVT) 9 promising sunflower accessions of the Institute's selection were isolated. The yield of sunflower lines for three years of study in the CVT ranged from 1.55 to 2.19 t/a. The highest increase in yield relative to the control variety Spartak was obtained in line 436, and amounted 0.12 t/ha.
Influence of weather conditions on the quality of sugar beet seeds
Authors: Подвигина О.А. , Сащенко М.Н.
Published: August 2024

Приведены результаты исследований,  в которых определено влияние погодных условий на формирование качества семян сахарной свеклы. Установлена положительная зависимость формирования недоразвитых семян от среднесуточной температуры и относительной влажности воздуха в период цветения семенных растений. Количество нормально выполненных семян разных лет выращивания колебалось в пределах 49,72–61,67 %. Семена невыполненные (пустые околоплодники и сформировавшие только один эндосперм), с дегенерирующими и недоразвитыми зародышами, с большим процентом отслоения зародыша от семенной оболочки относятся к невсхожим. Рентгенографический метод позволяет браковать такие семена, тем самым повышая качество посевного материала. 

The results of studies that determine the influence of weather conditions on the formation of the quality of sugar beet seeds are presented. A positive dependence of the formation of underdeveloped seeds on the average daily temperature and relative air humidity during the flowering period of seed plants has been established. The number of normally completed seeds from different years of cultivation ranged from 49.72 to 61.67 %. Unfulfilled seeds (empty pericarp and having formed only one endosperm), with degenerating and underdeveloped embryos, with a large percentage of the embryo detached from the seed coat are classified as non-germinating. The X-ray method makes it possible to reject such seeds, thereby increasing the quality of the seed.
INFORMATION RESOURCES FOR METHODOLOGICAL AND INSTRUMENTAL SUPPORT OF RESEARCH AIMED AT THE ASSESSMENT OF HEALTHCARE ECONOMIC EFFICIENCY PROJECTS
Authors:   Russian Research Institute of Health, Ministry of Health of the Russian Federation, KARMINA R.L. , KANEV A.F. ,   Russian Research Institute of Health, Ministry of Health of the Russian Federation, KURAKOVA N.G. ,   Russian Research Institute of Health, Ministry of Health of the Russian Federation, KOBYAKOVA O.S. ,   Russian Research Institute of Health, Ministry of Health of the Russian Federation, OBUKHOVA O.V. ,   Russian Research Institute of Health, Ministry of Health of the Russian Federation, KADYROV F.N. ,   Russian Research Institute of Health, Ministry of Health of the Russian Federation
Published: August 2024

Experts predict global health spending to reach $16.9 trillion by 2050. However, 20% to 40% of all resources invested could be lost due to various forms of project inefficiency. An analysis of the content of three key information resources offering methodological and instrumental support for research aimed at the assessment of the cost-effectiveness of projects implemented in national health care systems was carried out. The resources analyzed were the following: World Health Organization's Choosing Interventions that are Cost-Effective (WHO CHOICE), Guide to economic analysis and research (GEAR) and Disease control priorities (DCP). Each of the information resources provides unique, non-duplicate content that provides decisions making support based on data from assessment of the cost-effectiveness of projects and activities in the healthcare system. WHO-CHOICE uses a “generalized” approach to cost-effectiveness analysis, a standardized methodology that helps measuring the impact of health interventions and identifying priorities for further development. An interactive tool OneHealth, developed based on WHO-CHOICE, provides the ability to simulate a wide range of scenarios, strategies and their combinations. GEAR provides methodological support for cost-effectiveness assessment algorithms, including smart maps for decision-making, a database of practical guidelines and the opportunity to get an expert advice. The DCP provides access to an organized online collection of publications and generates a periodic review of the most relevant evidence on cost-effective interventions to address the burden of disease in the setting of scarce resources. It is concluded that the reviewed information resources effectively summarize international practices in analyzing the costeffectiveness of healthcare projects while still having a number of limitations for use in domestic research. The need to create our own accessible and regularly updated interactive tools for the economic assessment of medical interventions is substantiated, taking into account the national and regional characteristics of the functioning of the Russian Federation healthcare system.
أثر التمكين الإداري للقيادات النسائية على الأداء الوظيفي: دراسة تطبيقية على أحد القطاعات الحكومية بالمملكة العربية السعودية لعام 2023
Authors: شعراوي حسام حسن , السيد أماني صالح
Published: August 2024

ركزت الدراسة الحالية على أثر التمكين الإداري على الأداء الوظيفي للقيادات النسائية بالقطاع الحكومي في المملكة العربية السعودية لعام 2023، بالاعتماد على دراسة تطبيقية شملت عينة من 70 قائداً وقائدةً من أحد القطاعات الحكومية خلال الربع الثاني من العام 2023، وتوصلت الدراسة إلى وجود تأثير إيجابي ومعنوي للاتصال الفعّال "كأحد أبعاد التمكين الإداري" على الأداء الوظيفي للقيادات النسائية في هذا القطاع، كما بيّنت نتائج الدراسة عدم وجود تأثير معنوي لأبعاد التمكين الإداري للقيادات النسائية وهي: "تفويض السلطة، التدريب، التحفيز، فرق العمل"، بالرغم من أن نتائج تحليل الانحدار الخطي البسيط بينّت أن هذه الأبعاد لها تأثير إيجابي ومعنوي، وتعّد هذه الدراسة أول دراسة -على حد علم الباحثان- يتم تطبيقها على القيادات النسائية بالقطاع الحكومي في المملكة العربية السعودية.
On the specificity of aurintricarboxylic acid toward some phosphatases
Authors: Mitrasinovic Petar M.
Published: August 2024

Protein tyrosine phosphatases (PTPs) play vital roles in the intracellular signaling pathways associated with cell transformation, growth, and proliferation. In a variety of carboxylic acid derivatives, aurintricarboxylic acid (ATA) has been recognized as a binder of the largest affinity to the Yersinia PTP (YopH). Herein, the underlying specificity of ATA, as a reversible and competitive inhibitor of several PTPs (YopH, PTP1B, TCPTP, HePTP, CD45, VHR, and Cdc25A), is explored. By observing each PTP as a primary target receptor and the rest of them as simultaneous secondary receptors, the specificity factor, as a function of ligand concentration, shows at lower [ATA] (between 10-11 and 10-9 M) a 23 to 500-fold specificity in favor of YopH versus the other PTPs, indicating that the ATA-YopH interaction is the most specific. Near [ATA] = 10-8 M, the specificity factor ≈1 is associated with equal occupancy of the primary receptor YopH and the set of secondary receptors. When observing YopH as a primary receptor relative to every other single PTP as a secondary receptor at [ATA] ϵ (10-11, 10-9 M), the specificity to YopH is larger nearly 6, 25, 25, 40, 100, and 120 times than that to PTP1B, HePTP, CD45, TCPTP, Cdc25A, and VHR, respectively. The relative binding free energy contribution of every single YopH residue located in the active site (403-Cys-Arg-Ala-Gly-Val-Gly-Arg-Thr-410) and in the proximal WPD loop (352-Gly-Asn-Trp-Pro-Asp-Gln-Thr-Ala-Val-Ser-361) is evaluated using alanine-scanning mutagenesis. The so-called “hot spots” of binding affinity that dominate the interaction are found to be Trp354 and Thr358 to a greatest extent, as well as Gly352 to a somewhat lesser extent. Ser361 from the WPD loop is established to be inclined toward the destabilization of the ATA:YopH complex. Therefore, some experimental research based on isothermal titration calorimetry could establish which WPD loop residues weaken the interaction, thereby proving whether Ser361 plays a vital role in ATA binding or not.
Visible Light Driven α-Sulfonylation of Ketone-Derived Silyl Enol Ethers via Electron Donor-Acceptor Complex
Authors: SAXENA BARAKHA , I. Patel Roshan , Sharma Anuj
Published: August 2024

The diverse utility of β-ketosulfones in pharmaceuticals and bioactive compounds has generated considerable interest in their synthesis. However, existing synthetic approaches often depend on transition-metal catalysts, which require extensive purification and low yields. Herein, we present a cost-effective, metal-, photocatalyst-free, visible light electron donor-acceptor (EDA) complex-mediated sulfonylation of ketone-derived silyl enol ethers with thiosulfonates (acceptor) and DABCO as an electron donor under mild conditions, offering a more efficient and straightforward approach. Our method enables the synthesis of a diverse range of β-keto sulfone derivatives, including biologically active and late-stage molecules, in good yields. Our strategy offers several significant advantages over existing techniques, which include (i) transition-metal and photoredox catalyst-free; (ii) external SO2-source-free; (iii) broad substrate scope; (iv) recyclable and reusable by-product; (v) excellent atom economy, reaction mass efficiency, process mass intensity, and E-factor and EcoScale scores, highlighting its efficiency and economic sustainability. Detailed mechanistic studies confirm the involvement of an EDA-complex mediated radical process that operates without a catalyst.
Impact of charging in constant potential electrochemistry modeling
Authors: Kristoffersen Henrik
Published: August 2024

A huge issue in computational electrochemistry is that different modeling approaches, used to study electron transfer reactions, give different results and cannot easily be reconciled with each other. One discrepancy is their handling of interface charging. I study charging of electrolyte-Cu(111) interfaces with electrons and cations (or positive continuum charge) and observe that the charging energy depends strongly on the electrolyte model. When the electrolyte is a film containing water and KOH ions, there is a close to one-to-one stabilization of the energy with more negative potential, which fits with an ideal charging behavior, where the inserted cations-electron pairs do not repel each other. This is in strong contrast to the charging of an interface with implicit solvent, where the lack of electric-field screening result in large repulsion, which could give the erroneous impression that charging can be ignored in electrochemistry modeling. I also consider constant potential CO2 adsorption to highlight the importance of charging and using an electrolyte model with water and ions, and show that other modeling approaches gives significantly different and less stable CO2 adsorption energies.
Innovative L-band electron paramagnetic resonance investigation of solid-state pouch cell batteries
Authors: Dutoit Charles-Emmanuel , Soleti Raffaella , Doux Jean-Marie , Pelé Vincent , Boireau Véronique , Jordy Christian , Pondaven Simon , Vezin Hervé
Published: August 2024

Usually, the conventional electron paramagnetic resonance (EPR) spectroscopy and imaging use a microwave cavity operating at X-band, i.e. with an excitation frequency of around 9.6GHz, and remains the most popular mode in the magnetic characterization of lithium batteries to date. We provide here the first low-frequency EPR investigations for monitoring the metallic lithium structures in the solid-state pouch cell batteries. We show that L-band, i.e. a microwave frequency of around 1GHz, is an invaluable method to probe in depth the electrode components through a standard pouch cell using aluminum laminated film for packaging without opening the battery. These results offer a new approach for monitoring the nucleation of micrometric and sub-micrometric lithium particles such as dendritic lithium structures which is an important step in the development of reliable solid-state batteries.
Reprogramming of breast tumor–associated macrophages with modulation of arginine metabolism
Authors: Fernando Veani , Zheng Xunzhen , Sharma Vandana , Sweef Osama , Choi Eun-Seok , Furuta Saori
Published: August 2024

HER2+ breast tumors have abundant immune-suppressive cells, including M2-type tumor-associated macrophages (TAMs). Although TAMs consist of the immune-stimulatory M1 type and immune-suppressive M2 type, the M1/M2-TAM ratio is reduced in immune-suppressive tumors, contributing to their immunotherapy refractoriness. M1- versus M2-TAM formation depends on differential arginine metabolism, where M1-TAMs convert arginine to nitric oxide (NO) and M2-TAMs convert arginine to polyamines (PAs). We hypothesize that such distinct arginine metabolism in M1- versus M2-TAMs is attributed to different availability of BH4(NO synthase cofactor) and that its replenishment would reprogram M2-TAMs to M1-TAMs. Recently, we reported that sepiapterin (SEP), the endogenous BH4precursor, elevates the expression of M1-TAM markers within HER2+ tumors. Here, we show that SEP restores BH4levels in M2-like macrophages, which then redirects arginine metabolism to NO synthesis and converts M2 type to M1 type. The reprogrammed macrophages exhibit full-fledged capabilities of antigen presentation and induction of effector T cells to trigger immunogenic cell death of HER2+ cancer cells. This study substantiates the utility of SEP in the metabolic shift of the HER2+ breast tumor microenvironment as a novel immunotherapeutic strategy.
Helicobacter pyloriinduces the expression of Lgr5 and stem cell properties in gastric target cells
Authors: Nascakova Zuzana , He Jiazhuo , Papa Giovanni , Francas Biel , Azizi Flora , Müller Anne
Published: August 2024

Helicobacter pyloriinfection predisposes carriers to a high risk of developing gastric cancer. The cell-of-origin of antral gastric cancer is the Lgr5+stem cell. Here, we show that infection of antrum-derived gastric organoid cells withH. pyloriincreases the expression of the stem cell marker Lgr5 as determined by immunofluorescence microscopy, qRT-PCR, and Western blotting, both when cells are grown and infected as monolayers and when cells are exposed toH. pyloriin 3D structures.H. pyloriexposure increases stemness properties as determined by spheroid formation assay. Lgr5 expression and the acquisition of stemness depend on a functional type IV secretion system (T4SS) and at least partly on the T4SS effector CagA. The pharmacological inhibition or genetic ablation of NF-κB reverses the increase in Lgr5 and spheroid formation. Constitutively active Wnt/β-catenin signaling because ofApcinactivation exacerbatesH. pylori–induced Lgr5 expression and stemness, both of which persist even after eradication of the infection. The combined data indicate thatH. pylorihas stemness-inducing properties that depend on its ability to activate NF-κB signaling.
Implementasi Metode Profile Matching dalam Proses Seleksi Bantuan UMKM di Indonesia
Authors: Ardinata Richard , Pamungkas Wahyu Herlambang Putra , Permadi Wisnu Topo , Cholil Saifur Rohman
Published: August 2024

Pemerintah Indonesia memberikan bantuan Usaha Mikro, Kecil dan Menengah (UMKM) berupa dana dan pelatihan UMKM kepada pelaku UMKM di Indonesia. Dalam proses penerimaan bantuan UMKM tersebut masih banyak kendala yang dihadapi oleh petugas UMKM seperti proses seleksi masih membutuhkan waktu lama sehingga sering terjadi keterlambatan penerimaan bantuan UMKM. Selain itu, terdapat juga masalah dalam melakukan seleksi penerima bantuan UMKM, petugas bantuan UMKM masih melakukanya secara konvensional dan belum adanya standar untuk menghitung dalam melakukan proses seleksi dan harus menilai berdasarkan kriteria yang telah ada. Penelitian ini mengajukan solusi seleksi Penerima Bantuan UMKM  menggunakan algoritma Profile Matching. Dalam penerapan algoritma Profile Matching bekerja berdasarkan kriteria yang telah ditetapkan dengan memberikan hasil berupa perangkingan terhadap data pemohon bantuan UMKM. Adapun kriteria yang digunakan dalam penerimaan bantuan UMKM penerima bantuan aspek usaha UMKM yaitu: Jumlah Tenaga Kerja, Modal Awal, Lama Usaha, Omset, dan aspek prinsip 5C yaitu Character, Capity, Capital, Collateral, Conditions.
Perancangan Sistem Pengelolaan Dana Bantuan Desa Kembangarum Menggunakan Metode AHP
Authors: Ajimas Putra Mahendra Firdaus , Hilmi Hakim Muhammad Aufa , Rifai Fathur Fajar
Published: August 2024

Mengelola dana bantuan desa secara efektif dan efisien merupakan salah satu tantangan terbesar dalam meningkatkan kesejahteraan masyarakat desa. Desa Kembangarum menghadapi kendala dalam pengalokasian dana bantuan yang seringkali tidak tepat sasaran dan kurang transparan. Penelitian ini bertujuan untuk merancang sistem pengelolaan dana bantuan desa dengan menggunakan metodologi Analytic Hierarchy Process (AHP). Metode AHP dipilih karena memungkinkan pengambilan keputusan yang kompleks berdasarkan berbagai kriteria. Sistem ini digunakan untuk mengidentifikasi, menganalisis, dan memprioritaskan kebutuhan pendanaan bantuan berdasarkan berbagai kriteria yang relevan seperti urgensi, dampak, dan ketersediaan sumber daya. Hasil studi menunjukkan bahwa penggunaan metodologi AHP dalam sistem pengelolaan  bantuan desa  meningkatkan akurasi dan transparansi alokasi dana serta memastikan  dana bantuan dialokasikan sesuai dengan prioritas kebutuhan masyarakat. Penerapan sistem ini diharapkan dapat menjadi model yang efektif dalam pengelolaan  bantuan di desa-desa lainnya.
Pengukuran Kualitas Perangkat Lunak Manager.io pada Model FUPRS
Authors: Vidiasasti Wangi , Ningtris Wahyu Utami , Wicaksono Soetam Rizky
Published: August 2024

Pengukuran ini bertujuan untuk mengukur kualitas perangkat lunak sistem informasi akuntansi Manager.io menggunakan metode FUPRS (Functionality, Usability, Performance, Reliability, dan Supportability). Fokus utama terletak pada tiga dimensi: functionality, usability, dan performance. Evaluasi functionality dilakukan melalui identifikasi dan pemetaan fitur utama serta pengujian untuk memastikan setiap fungsi bekerja sesuai dengan spesifikasi. Usability dievaluasi berdasarkan umpan balik pengguna, efisiensi penggunaan, dan konsistensi antarmuka. Performance diukur melalui pengujian kinerja di bawah berbagai kondisi beban kerja, termasuk respon waktu dan efisiensi pemrosesan data. Hasil menunjukkan bahwa Manager.io memiliki fitur akuntansi yang lengkap dan fleksibel, kemudahan penggunaan yang tinggi, serta kinerja yang responsif. Namun, perangkat lunak ini memiliki keterbatasan dalam interoperabilitas dan aspek keamanan yang perlu ditingkatkan. Metode FUPRS terbukti efektif dalam memberikan evaluasi yang komprehensif dan fleksibel sesuai kebutuhan spesifik, memastikan perangkat lunak ini dapat memenuhi kebutuhan saat ini dan masa depan.
The utilization of banana peels (Musa acuminata Cavendish subgroup) as an
alternative ingredient for producing dried plant-based meat products
Authors: Issara U. , Tiwasiri N. , Keawwong P. , Lamphao O. , Chana S. , Sangketkit W. , Changpasert W.
Published: August 2024

The utilization and value-added of agricultural by-products have been highlighted for the
novel development of food and non-food products nowadays. This study aimed to produce
the dried plant-based meat prototype using banana peels to substitute the textured
vegetable protein (TVP) and characterize their properties. Banana peels (state 2 or 3 of
maturity) were collected and washed to reduce contamination. The pesticide residues and
the characteristics (chemical composition and antioxidant activity) of banana peel were
analyzed before use. The meat sample (mixed with ingredients such as TVP, banana peel,
sugar, salt, pepper, and other components) was prepared, shaped, and dried in the oven (at
80oC) until the moisture content was lower than 15% and divided for four treatments with
different proportions of TVP and peels at the concentrations of 0, 25, 50, and 75 %w/w.
The physical and physicochemical properties (color, pH, Aw, texture profile), chemical
compositions, biological activity, microbiological test, and sensory evaluation (color,
flavor, texture, appearance, and overall liking as well as acceptability) were determined.
The results revealed a significantly reduced L
*
, a
*
, and b
* value (p<0.05) with an increase
in banana peels added ratio. The different pH and Aw values were not observed in all
treatments (p>0.05). There was no significant difference (p>0.05) was observed in protein
content among group treatments compared to the control. The meat sample showed a
slightly softer texture when compared to the control (p<0.05). There were no pathogenic
microorganisms observed in the meat samples. The overall liking (obtained from 30
panelists) was moderately desirable (5.50 points) from the consumer testing. Moreover,
50% (w/w) of substitution showed the highest score (43.3%), while the control was 33.3%
on the acceptability test. According to the results, banana peels could be used as an
alternative ingredient for substitute TPV in plant-based meat products. These findings
could be helpful for the fundamental data to develop plant-based meat to meet consumer
requirements.
É POSSÍVEL UM DIÁLOGO INSTITUCIONAL NA DESCRIMINALIZAÇÃO POSSE DE MACONHA?
Authors: Melo Ellen Cristine Alves de , Cirne Mariana Barbosa
Published: August 2024

Esse artigo analisa se é possível um diálogo institucional entre os Poderes Judiciário e Legislativo sobre a descriminalização da conduta de posse de maconha. Esse tema é relevante porque trata de tema de saúde pública, e de política criminal, muito pesquisado na academia. Discute, ainda, caminhos para a crise da separação de poderes. Com esse estudo, busca-se responder se: é possível um diálogo institucional entre os Poderes Legislativo e Judiciário no julgamento do RE nº 635659, com repercussão geral reconhecida (Tema 506), e na PEC/45/2023, para tratar da descriminalização da maconha? Para respondê-la, analisou, de um lado, a crise da legislação, e de outro, a supremocracia. Defende o diálogo institucional defendido por Conrado Hubner Mendes, como um possível caminho entre os extremos, a partir da argumentação jurídica. A pesquisa detém natureza qualitativa, empírica, com o uso de pesquisa bibliográfica, levantamento documental das manifestações e justificativas legislativas para a PEC nº 45, de 2023, pedidos de acesso à informação aos poderes, das decisões do STF, e da busca nos sites de notícias do STF e do Senado Federal sobre a posição das instituições. Concluiu que não existe um diálogo entre os poderes sobre o tema da descriminalização da maconha. As discussões se centram no reforço de suas próprias competências institucionais, sem abertura para os temas constitucionais envolvidos. Ao agregar pesquisas acadêmicas sobre o tema, e apresentar a ausência de diálogo, espera-se contribuir com uma mudança de postura entre os poderes, que possa garantir de maneira mais efetiva os direitos fundamentais.
DIREITO À SAÚDE, POLÍTICAS PÚBLICAS E DECOLONIALIDADE: UMA ANÁLISE DECOLONIAL DA INCLUSÃO DE CORPOS TRANSEXUAIS NAS POLÍTICAS PÚBLICAS DE SAÚDE
Authors: França Lima Marques Cláudia Marilia , Machado Sturza Janaína , Scola Dutra Gabrielle
Published: August 2024

O pensamento colonial estabeleceu a noção de que existe um padrão ideal de corpo, que é branco e cis-heteronormativo. Esse corpo universal influencia na elaboração das políticas públicas relacionadas ao acesso aos serviços de saúde e exclui corpos transexuais, que não se enquadram nesse recorte. Assim, surge a necessidade de debater sobre o desenho das políticas públicas a partir do pensamento decolonial. Diante disso, a pesquisa questiona como ocorre a criação do corpo ideal a partir da lógica do poder colonial e da hierarquização das raças e aborda as barreiras que as pessoas transexuais enfrentam ao tentarem acessar o direito à saúde. Após, o trabalho reflete sobre a necessidade da criação de políticas públicas a partir do pensamento descolonial, a fim de considerar todos os marcadores que permeiam os corpos. Ressalta-se que a pesquisa é desenvolvida pelo método dedutivo e é bibliográfica. Como conclusão, o estudo aponta que a descolonização do pensamento é uma alternativa para elaborar políticas públicas relacionadas ao direito à saúde que considerem as especificidades das pessoas transexuais.
A TUTELA JURÍDICA COMO INSTRUMENTO DE INCLUSÃO E IGUALDADE PARA PESSOAS OBESAS OU COM SOBREPESO NO BRASIL
Authors: GOMES NAIR DE FÁTIMA , VIEIRA TEREZA RODRIGUES
Published: August 2024

RESUMO: Com base no método hipotético-dedutivo, contemplando a revisão bibliográfica de obras doutrinárias, periódicos e legislação, o presente trabalho tem por objetivo analisar a falta de atenção, os desafios e o   apoio aos indivíduos obesos ou com sobrepeso, segundo a perspectiva da dignidade humana como direito fundamental dessas pessoas estereotipadas e estigmatizadas pela sociedade em geral. Comumente, acontecem episódios de preconceito e discriminação enfrentados por aqueles que sofrem com a obesidade ou sobrepeso. Recentemente, as normas jurídicas têm considerado esse tema, reconhecendo a obesidade crescente como uma questão que precisa ser reavaliada e atendida para que essas pessoas possam viver dignamente. Dessa forma, é crucial abordar a discriminação relacionada ao excesso de peso como uma forma de preconceito, semelhante à discriminação com base em raça e gênero. Para tanto, esse grupo vulnerável necessita de um documento de âmbito nacional que proteja seus direitos, aplicando-se os direitos constitucionais que permeiam e sustentam todo o sistema normativo em vigor. Em algumas regiões brasileiras, já é observado um significativo avanço jurídico e social por meio de leis que buscam criar dispositivos para inclusão, acessibilidade e proteção das pessoas obesas. Contudo, essa responsabilidade não recai apenas sobre o Estado, mas também sobre a coletividade. Assim, considerando a relevância do tema, uma vez que a obesidade é divulgada como deficiência, é imperativo continuar promovendo medidas legais e sociais que garantam a igualdade e o respeito aos direitos fundamentais desses indivíduos.
A BANALIDADE DO MAL E A PANDEMIA DA COVID-19 NA CIDADE DE MANAUS/AM
Authors: Teixeira da Costa Ruan Patrick , Nahmias Melo Sandro
Published: August 2024

O presente trabalho traça um paralelo entre a banalidade do mal (conceito tratado por Hannah Arendt) existente na sociedade e os desdobramentos da pandemia do novo coronavírus (covid-19), a qual atingiu praticamente todos os países do globo terrestre, resultando na morte de milhões de pessoas e um colapso nos sistemas de saúde, que não estavam preparados para um evento dessa magnitude. A cidade de Manaus, no início do ano de 2021, foi o epicentro da doença no Brasil, com alto número de casos confirmados, bem como de óbitos, resultado de um conjunto de fatores, entre eles a ausência de um bom sistema de saúde e uma gestão ineficiente das esferas governamentais (municipal, estadual e federal) no que diz respeito à área da saúde. A metodologia utilizada foi a pesquisa bibliográfica, por meio da coleta de dissertações e artigos a respeito da matéria. Da análise feita, foi possível verificar que a ineficiência da gestão pública, juntamente com a não adesão de parte da população sobre os protocolos de prevenção previstos pela Organização Mundial de Saúde (OMS) para o enfrentamento da doença demonstram como o ser humano, quando desprovido de um mínimo senso de responsabilidade em relação ao próximo ou mesmo de racionalidade política para refletir sobre o que ocorre ao seu redor pratica o mal de forma banal e prejudica uma enormidade de pessoas.
DIREITO ELEITORAL, DIREITOS POLÍTICOS E AGENDA 2030: UM DIÁLOGO COM ENFOQUE HABERMASIANO
Authors: De Freitas Junior Luciano Mamede , Veloso Roberto Carvalho
Published: August 2024

O direito eleitoral e os direitos políticos compõem um sistema democrático, desempenhando papéis essenciais na garantia da participação cidadã, expressando suas escolhas por meio do voto, sendo essencial para a legitimidade do governo, pois reflete a vontade popular. Os direitos políticos, a democracia e a Agenda 2030 são temas interconectados que abordam questões fundamentais relacionadas à participação cidadã, governança justa e desenvolvimento sustentável. O presente trabalho aborda a perspectiva dos direitos políticos e a Agenda 2030 sob enfoque de Habermas, tratando da discussão sobre a base democática desses direitos, perpassando sobre o debate dos princípios do direito eleitoral na implantação da Agenda 2030. Trata-se de uma pesquisa bibliográfica realizada pelo método sociojurídico-crítico, precedida de pesquisa documental, básica, estratégica e com uma abordagem qualitativa.  As instituições envolvidas com o processo eleitoral brasileiro devem estar comprometidas com a agenda 2030 da ONU, promovendo alterações legislativas quando necessárias, assim como primando pelos compromissos assumidos pelas instituições em meio aos processos eleitorais.
A EFETIVIDADE DA BUSCA ATIVA NA PROMOÇÃO DO DIREITO FUNDAMENTAL À CONVIVÊNCIA FAMÍLIA DE CRIANÇAS E ADOLESCENTES: ESTUDO DE CASO DAS ADOÇÕES VIABILIZADAS PELO "A.DOT" NO ESTADO DO PARANÁ NOS ÚLTIMOS 5 ANOS
Authors: Da Silva Cristiano Diniz , Morelato Lorany Serafim , Cummings Malcon Jackson
Published: August 2024

O artigo tem por objetivo analisar se o aplicativo "A.dot" trouxe maior efetividade aos processos relacionados à adoção de crianças e adolescentes que não se enquadrem no perfil de preferência pelos adotantes no Estado do Paraná. A metodologia utilizada é, inicialmente, a pesquisa bibliográfica, para conceituar os eventos e entender as discussões já travadas até então. Em seguida, foi realizada pesquisa empírica com análise qualitativa de dados e estudo de caso, viabilizado por pesquisa documental. Foram levantados os dados de adoções realizadas em nível nacional, no Estado do Paraná e aquelas viabilizadas pelo aplicativo A.dot, entre 2019 e 2023. No âmbito estadual os dados foram fornecidos pela Comissão Estadual Judiciária de Adoção do Estado do Paraná – CEJA/PR e pelo Conselho de Supervisão da Infância e Juventude do Estado do Paraná – CONSIJ/TJPR. Como resultados, a pesquisa apresenta uma análise comparativa do desempenho de adoções tardias no Estado do Paraná e no Brasil, buscando estabelecer a influência da utilização do aplicativo A.dot nesses números.  Conclui-se que há indicativos de que o aplicativo A.dot tem sido efetivo para o fim que se propõe, notadamente em razão do alto número de adoções de adolescentes que foram viabilizadas e pela constatação de que o Estado do Paraná apresenta percentual de adoções tardias significativamente maior que a média nacional.
O DIREITO DE AÇÃO COMO FERRAMENTA DE GARANTIA AO ACESSO À JUSTIÇA NO BRASIL E ARGENTINA
Authors: De Sousa Milhomem Maria José Carvalho
Published: August 2024

O presente artigo objetiva fazer um estudo comparativo entre Brasil e Argentina, abordando o Direito de acionar a justiça, a ação como base ou nascimento da ciência do direito processual, assim como a divisão dos poderes e a contitucionalização do direito de acionar, fazendo uma breve análise a respeito dos pactos e tratados internacionais e ainda a respeito do direito fundamental do acesso à justiça, como o acesso irrestrito, a garantia de igualdade e a desigualdade económica, demonstrando que no Brasil, o jurisdicionado se utiliza a assistência judiciaria gratuita e da justiça gratuita como mecanismo de efetivação de ingresso na justiça e na Argentina do benefício de litigar sem gastos, analisando suas diferenças e similitudes para sugerir mudanças a fim de aprimorar esses sistemas. Em relação à metodologia, utilizou-se no presente estudo o método dedutivo, com procedimentos de pesquisa bibliográfico e documental, com abordagem descritiva-exploratória. Enfrentou-se a análise da legislação, doutrina e jurisprudência sobre a temática abordada.
OS JUDICIÁRIOS NA AMÉRICA LATINA: REFORMAS E INFLUÊNCIAS PARA FORMAÇÃO DE UM SISTEMA DE JUSTIÇA CONSTITUCIONAL
Authors: Barros Teresa Helena
Published: August 2024

O presente trabalho buscou fazer uma investigação sobre as reformas que aconteceram no âmbito do Poder Judiciário, a partir de um recorte temporal que se inicia após a ditadura militar, perpassa pela promulgação da Constituição Federal em 1988 e finaliza com a Emenda Constitucional 45/2004. Para isso, o primeiro capítulo discutiu o contexto das reformas que ocorreram na América Latina, isto porque, durante o trabalho, ficou evidente que seria impossível compreender o padrão das reformas legislativas no Brasil sem estudar as experiências latino-americanas quanto à reforma do Judiciário a partir da influência de determinadas organizações, como o Banco Mundial. Abordou-se também a participação de atores específicos para as alterações que ocorreram na legislação brasileira, com enfoque nas repercussões políticas da promulgação da EC 45/2004 e seu impacto na atuação do Poder Judiciário. Após essa contextualização, o capítulo seguinte trouxe um debate sobre a Constituição Federal de 1988 e a democratização do judiciário. A partir dessas questões, objetivou-se fazer uma relação entre as reformas que aconteceram no Judiciário brasileiro e o caminho percorrido para o fortalecimento do sistema de justiça constitucional. A metodologia do presente trabalho foi bibliográfica e exploratória, utilizando-se de doutrinas e o acervo nos repositórios.
Sifat Sensoris, Kadar Protein dan Zat Besi pada Cookies Daun Kelor
Authors: Novitaroh Ana , Sulistiani Ria Purnawian , Isworo Joko Teguh , Syadi Yunan Kholifatudin
Published: August 2024

Cookies are high-energy and sugar snack that is popular in adolescents. Adolescents have a risk of infected anemia. One ingredient food that contains protein and iron which is good forpreventing anemia is Moringa oleifera L leaves. This study aims to determine the effect of addingMoringa leaves on sensory properties, protein, and iron levels in cookies. This research is usingthe True Experiment method with a Completely Randomized Design (CRD). The number ofvariations in the treatment in this study was P0=0 grams of moringa leaves, P1=5 grams, P2=10grams, P3=15 grams. Test for sensory properties using the hedonic test, the protein content testused the Kjedahl method and the iron test used the Spectrophotometric method. The statisticaltest of protein and iron levels used ANOVA. The results showed the best treatment is cookies withthe addition of 10 grams of Moringa leaves (P2). The highest protein content in P3 was 24.609%,and the lowest at P0 18.023% and showed significant differences between treatments. The highestof iron levels in P3 0.015%, and the lowest at P0 0.003% and showed significant differencesbetween treatments. The addition of moringa leaves to cookies affects sensory properties,increases levels of protein and iron.Keywords : Cookies, moringa leaves, protein, iron, sensory properties
Analisis Ahli Cakram Asupan Makan dan Cairan Atlet: Studi Awal Pengembangan Media Edukasi Atlet Remaja
Authors: Afriani Yuni , Sari Siska Puspita , Puspaningtyas Desty Ervira
Published: August 2024

Many young athletes have undernourished nutritional status, lack of knowledge, and improperselection of nutritional intake. It has an impact on the success of athletes when conducting games.One of the contributing factors is the suboptimal use of educational media for athletes.Educational media, Cakram is one of the alternative media that needs to be developed and appliedto young athletes. Cakram Asupan Makan dan Cairan Atlet (CAMCA) is an educational mediainnovation that makes it easier for athletes. This study aims to analyze the level of mediaacceptance of Cakram Asupan Makan dan Cairan Atlet (CAMCA) conducted on experts in thefield of Sports Nutrition as a solution to athletes' health independence, especially optimizing thenutritional status of adolescent athletes. This research was a quantitative descriptive study. Thisresearch began with the manufacture and development of cakram by looking at the level ofacceptance of Cakram Asupan Makan dan Cairan Atlet (CAMCA) media by experts in the field ofSports Nutrition. Data were analyzed descriptively. Nutrition education media in the form ofCakram Asupan Makan dan Cairan Atlet (CAMCA) is very interesting media to be developed andapplied to young athletes related to the fulfillment of nutritional intake.Keywords: young athletes; cakram gizi; educational media; athlete performance
Hubungan Pengetahuan Gizi Ibu, Pendapatan, Ketahanan Pangan Keluarga dengan Status Gizi Siswa MTs Muhammadiyah Pemalang
Authors: Oktaviasih Astri Ayu , Sartono Agus , Susantini Purwanti , Ayuningtyas Rr. Annisa
Published: August 2024

Adolescence is a unique period in terms of behavior to meet nutritional needs. The nutritional status of the adolescent is interfered with by sociodemographic variables. This study aims to analyze the relationship between mother’s nutritional knowledge, income, and household food security with the nutritional status of students at MTs Muhammadiyah 02 Pemalang. A cross-sectional study was conducted on 76 students selected by systematic random sampling. The respondents of this study are the mother and the family. Data on mothers’ nutrition knowledge, family income, and food security were collected using questionnaires. The relationship of the variables was analyzed by Pearson correlation. The study found that 22.4% of students are underweight, and 11.8% of students are overweight. 52.6% of respondents haveadequate nutrition knowledge, 40.8% of respondents' families have low income, and 57.9% are food insecure. There is no relationship between mothers’ nutritional knowledge and family food security (p =0.099), there is a relationship between mothers’ nutritional knowledge and student nutritional status (p =0.014), there is a relationship between family income and student nutritional status (p = 0.000), there is no relationship between food security families with the nutritional status of students (p = 0,888). Mothers’ nutritional knowledge and family income are related to the nutritional status of the student.Keyword : Food security, income, mother’s nutritional knowledge, nutritional status
Hubungan Asupan Kalium dengan Hipertensi pada Perempuan Etnis Minangkabau
Authors: Usfa Marwanda Da , Hasni Dita , Birman Yuliza , Febrianto Budi Yulhasfi
Published: August 2024

Background : Hypertension is a blood pressure disease, where there is an increase in systolic (≥140 mmHg) and/or diastolic (≥ 90 mmHg) blood pressure quickly or slowly. Objective : This study aims to determine the relationship between potassium intake and the incidence of hypertension in inangkabau ethnic women. Methods : This research is a type of analytical research with a case control research design. The population in this study were all Minangkabau ethnic women who suffered from hypertension who went to the Air Padang Children's Health Center, with 114 samples that met the inclusion and exclusion criteria. Bivariate and univariate data analysis is presented in the form of frequency distribution and percentage, and the data is processed using the SPSS program. Result : This study showed that as many as 112 people (98.2%) of Minangkabau ethnic women with less potassium intake, and 2 people (1.8%) with adequate potassium intake. The average potassium intake in the hypertensive women group was 855.0146 mg, while the nonhypertensive women group was 1699.5777 mg. Hypertensive women have an average systolic blood pressure of 151.44, while a diastolic blood pressure of 92.09. Women without hypertension had an average systolic blood pressure of 111.49, while a diastolic blood pressure of 76.93. Less potassium intake was found in the hypertensive women group, namely 57 people (100%) compared to the nonhypertensive women group, namely 55 people (96.5%). Conclusion : There is no significant relationship between potassium intake and blood pressure in Minangkabau ethnic women.  Keywords: Hypertension, Potassium, Minangkabau
Manajemen Sekolah Sebagai Pilar Penyelenggaraan Kantin Sehat
Authors: Kadaryati Sri , Prasetyaningrum Yunita Indah , Sukismanto - , Wulan Yuni Kartika , Wardani Desy Fitria , Nareswara Angelina Swaninda
Published: August 2024

Eating habits, nutritious and safe food intake are greatly determined the nutritional status  of school-age children and adolescents. Eating habits acquired during adolescence will have an impact on adulthood and the elder. Overweight and obesity increased not only occur in adults, but also in adolescents. A school is a place where children spend more time every day than at home. Therefore, it needs to be considered food provision in schools. This study provides an overview of the readiness of school management in implementing healthy canteens in schools. This was qualitative research with a case study approach. The research was conducted at SMP Negeri 4 Depok Sleman Yogyakarta from June to August 2022. Data were collected using in-depth interviews involving principals and teachers as narasumberts. The study has obtained an Ethical Clearance from Komisi Etik Penelitian Kesehatan, Fakultas Ilmu Kesehatan, Universitas Respati Yogyakarta. The results showed that the school had prepared buildings and physical facilities in the canteen. The policy of providing healthy food was indicated by menu selection with restrictions on products high in sugar and salt, as well as the selection of safe serving utensils. This policy was agreed upon by the seller in the cooperation agreement between the school and the seller. Supervision systems were implemented by appointing healthy canteen management teams. Based on the results of this study, it was concluded that school management was committed to realizing a healthy canteen in schools. Policies regarding the provision of healthy food can be improved by adding menu choices from the vegetable group. Food safety can be improved by setting the serving time of food served.Keywords: healthy canteen, school management, principals, teachers
Tingkat Kesukaan The Angel Pastry dengan Substitusi Tepung Bonggol Pisang dan Daun Mangga
Authors: Yuniastuti Silvi Dwi , Restiana Meira , Alfiyanti Salma , Soesanto Edy , Maharani Putri , Aisyah Siti
Published: August 2024

One of the local food ingredients that can be used as a base for making pastry as an alternative diet for obesity in children is banana tubers and mango leaves. Banana stems and mango leaves can be processed into flour which can reduce damage and increase added value. Banana hump flour and mango leaves can be processed into various snacks, one of which is The Angel Pastry. The higher fiber and antioxidant content by substituting banana hump flour and mango leaves in the angel pastryhas the potential to be a filling snack. The aim of this research was to determine the level of preference for The Angel Pastry formulation with the substitution of banana hump flour and mango leaves. The experimental design used in this research was RAL (Completely Randomized Design). The substitution formulation for banana hump flour and mango leaves in making The Angel Pastry is 0,15, and 30%. The resulting Angel Pastry will be tested for the level of liking of 30 semi-trained panelists. The results showed that the substitution of banana hump flour and mango leaves had asignificant effect on the parameters of color, aroma, taste and texture preference level. Substitution of banana hump flour and mango leaves in making The Angel Pastry at 15% is the best treatment with a color preference level value of (4.72); aroma (4.89); taste (4.48); texture (4.82).Keywords: the angel pastry,banana flour, mango leaves, sensory evaluation
PERBANDINGAN EFEKTIVITAS CEFOTAXIME DAN CEFTRIAXONE PADA PASIEN RAWAT INAP PEDIATRI DENGAN PNEUMONIA
Authors: Rosnarita Intan Adevia , Akhyasin Akhtyasin , Dewi Sintia Kusuma
Published: August 2024

The prevalence of pneumonia for pediatrics in Indonesia is quite high. This condition is a concern for clinicians, especially pharmacists in handling the treatment of pneumonia in pediatrics. Treatment of pneumonia for pediatrics needs antibiotic therapy such as cefotaxime and ceftriaxone. This study aims to compare the effectiveness of the use of antibiotics cefotaxime and ceftriaxone in pediatric pneumonia patients at the inpatient installation of RSI Sunan Kudus Period February-April 2021. This study is a non-experimental research study with an observational analytic character, with purposive sampling, statistical analysis was carried out To compare the effectiveness of using cefotaxime and ceftriaxone based on duration of use and clinical symptoms, SPSS was performed using Paired T-Test. Based on the average duration of use for antibiotics cefotaxime 5 days and ceftriaxone 4.41 days. There was no difference in the average use of cefotaxime and ceftriaxone based on clinical symptoms such as cough, retractions, fever, shortness of breath and sore throat. The results of statistical analysis showed that ceftriaxone was more effective than cefotaxime in pediatric pneumonia, while there was no significant difference between ceftriaxone and cefotaxime (α) 0.05. The use of ceftriaxone is more effective in treating pediatric pneumonia than cefotaxime.
PENGARUH KONSENTRASI VARIASI BASIS CERA ALBA TERHADAP UJI EVALUASI MUTU FISIK SEDIAAN LIP BALM EKSTRAK KULIT BUAH NAGA MERAH (Hylocereus polyrhizus)
Authors: Sukoharjanti Bintari Tri , Murharyanti Rika , Hasriyani Hasriyani , Prastiwi Oktaviani Setiya
Published: August 2024

Kosmetik lip balm merupakan bahan pemakaian bagian luar tubuh  terutama pemakaian pada bibir. Lip balm terkenal melembabkan area pemakainya. Kulit buah naga merah dipakai sebagai ekstrak dan bahan aktif  inovasi bahan alam yang dapat dijadikan sediaan lip balm dengan basis cera alba berbeda. Kulit buah naga memiliki manfaat seperti flavonoid, tanin, dan alkaloid yang diketahui memiliki senyawa antioksidan. Penelitian ini bertujuan mengetahui pengaruh variasi konsentrasi basis cera alba dan evaluasi mutu fisik yang baik dengan formulasi tepat memenuhi persyaratan lip balm. Penelitian ini menggunakan metode eksperimental untuk melihat basis tepat diantara ketiga formula basis konsentrasi yang dipakai 5%, 15%, 25% dengan parameter uji organoleptik, uji homogenitas, uji pH, uji daya lekat, uji daya sebar. Pengujian selanjutnya yaitu uji topikal dan uji iritasi pada manusia. Metode ekstraksi maserasi menggunakan pelarut etanol 96%. Analisis dengan SPSS 25. Hasil Formula basis cera alba variasi basis F1 5%, F2 15% dan F3 25%, ekstrak kulit buah naga 14,5%. Hasil mutu fisik menunjukkan ketiga formula berwarna coklat, khas ekstrak dan mawar, tekstur lembut, F3 bertekstur keras,  F2 semi padat, F1 mudah hancur. Uji pH F1, F2, F3 memiliki rentang stabil pH-6. Daya lekat F1, F2, F3 memenuhi persyaratan 1 detik, kecuali uji homogenitas dan daya sebar. Uji topikal pada manusia didapatkan hasil merata, pada uji iritasi tidak ada gejala apapun sehingga aman digunakan. Secara karakteristik formula-2 memenuhi persyaratan sebagai sediaan lip balm yang baik dan aman digunakan.  Kata Kunci : Cera alba, uji evaluasi mutu fisik, kulit buah naga merah (Hylocereus polyrhizus), lip balm.