bluuebunny/crossref_metadata_2025 huggingface dataset:
Musician Advantage for Segregation of Competing Speech in Native Tonal Language Speakers
Authors: Liu Yang-wenyi , Cheng Xiaoting , Ding Chenru , Galvin John J. , Chen Bing , Fu Qian-Jie
Published: August 2024

The aim of this study was to replicate previous English-language musician advantage studies in Mandarin-speaking musicians and nonmusicians. Segregation of competing speech, melodic pitch perception, and spectro-temporal pattern perception were measured in normal-hearing native Mandarin-speaking musicians and nonmusicians. Speech recognition thresholds were measured in the presence of two-talker masker speech. The masker sex was either the same as or different from the target; target and masker speech were either co-located or spatially separated. Melodic pitch perception was tested using a melodic contour identification task. Spectro-temporal resolution was measured using a modified spectral ripple detection task. We hypothesized that, given musician advantages in pitch perception, musician effects would be larger when the target and masker sex was the same than when different. For all tests, performance was significantly better for musicians than for nonmusicians. Contrary to our expectation, larger musician effects were observed for segregation of competing speech when the target and masker sex was different. The results show that musician effects observed for non-tonal language speakers extend to tonal language speakers. The data also suggest that musician effects may depend on the difficulty of the listening task and may be reduced when listening tasks are too easy or too difficult.
The Effect of Social Anxiety on Inauthentic Self-Presentation in Instagram Users
Authors: Nisrina Zahra  , Amri Hana Muhammad
Published: August 2024

Instagram is one of the social media that is widely used to present ourself. However, this is believed to hurt its users because uploaded photos or videos on Instagram tend to be inconsistent with reflections from their daily lives which are then termed inauthentic self-presentation. Inauthentic self-presentation is the degree of contradiction between the self-presentation displayed on social media and the everyday life expressed by individuals. The phenomenon of inauthentic self-presentation is driven by various factors, one of which is a high level of social anxiety. Social anxiety is understood as anxiety or fear that arises because of the possibility of bad judgment from others when faced with certain social situations. Individuals with social anxiety tend to have concerns about negative evaluations from others and feel that they will do something embarrassing, so they develop inauthentic self-presentations to deal with the anxiety they experience. This study aimed to determine the effect of social anxiety on the inauthentic self presentation of Instagram users. This type of research is correlational quantitative. The sampling technique used quota sampling with a total sample of 120 people. The data analysis used is Pearson Product Moment with the help of a data processing program. Based on the study results, they obtained that the r Pearson’s value was 0.765. These results indicate that the hypothesis in this study, namely "there is an influence of social anxiety on inauthentic self-presentation on Instagram users" is accepted
Nutrition, GH/IGF-1 signaling, and cancer
Authors: Fanti Maura , Longo Valter D
Published: August 2024

Cancer is the second leading cause of death in the United States and among the most prevalent diseases globally, with an incidence expected to grow because of smoking, pollution, poor dietary habits, obesity, and the rise in the older population. Given their ability to reduce risk factors, albeit with varying efficacy, nutrition and fasting could help prevent cancer and other age-related disorders. Calorie restriction (CR), various forms of intermittent fasting (IF) or periodic fasting (PF), and fasting-mimicking diets (FMDs) have been shown to improve health span, increase lifespan, and prevent or postpone cancer in rodents. The effects of specific diets and fasting regimens on aging and cancer appear to be mediated in part by the reduction in the activity of the growth hormone (GH)/insulin-like-growth-factor-I (IGF-1) axis. Nevertheless, recent data indicate that the alternation of low and normal levels of these hormones and factors may be ideal for optimizing longevity and function. Here, we review the role of nutrition, CR, and fasting/FMD on cancer, focusing on the hypothesis that the modulation of GH, IGF-1, and insulin signaling partly mediates the effect of these dietary interventions on cancer prevention.
The association between BMI and BRAFV600E mutation may differ by primary tumor size
Authors: Park Hyunju , Heo Jung , Ryu Hyun Jin , Kim Min-Ji , Oh Young Lyun , Kim Tae Hyuk , Kim Sun Wook , Chung Jae Hoon
Published: August 2024

Objective

Previous reports suggest that a high body mass index (BMI) increases the risk of thyroid carcinoma. However, it remains unclear whether a high BMI is associated with the risk of the BRAFV600E mutation. We aimed to assess whether a high BMI is associated with an increased risk of the BRAFV600E mutation.

Design and Methods

We screened 6558 PTC patients who had undergone BRAFV600E mutation testing between January 2009 and December 2017. After exclusion, 6438 PTC patients were enrolled. We used logistic regression, and restricted cubic spline plots of the adjusted odds ratios (ORs) were illustrated to model the relationship between BMI and the BRAFV600E mutation.

Results

Of the 6438 patients, 5102 (79.2%) had the BRAFV600E mutation, and 4954 (76.9%) were female. The median BMI was 23.8 (21.6–26.2) kg/m2. The primary tumor size was ≤1 cm in 4226 patients (65.6%) and >1 cm in 2212 patients (34.4%). The BRAFV600E mutation was significantly associated with high BMI only in patients with a primary tumor size >1 cm (OR: 1.034; 95% CI: 1.003–1.065; P = 0.029), whereas no clear association was found in patients with a primary tumor size ≤1 cm (OR: 1.007; 95% CI: 0.984–1.030; P = 0.570). Gender was not a significant factor in either group.

Conclusions

Our study found that a higher BMI was positively associated with the BRAFV600E mutation in patients with a primary tumor size >1 cm. These results suggest that the association between BMI and the BRAFV600E mutation status differs depending on primary tumor size.

Significance Statement

Obesity has been suggested as a potential risk factor for thyroid carcinoma. The aim of this study was to assess the association between BMI and the BRAFV600E mutation. In this study, the BRAFV600E mutation was significantly associated with a high BMI only in a primary tumor size >1 cm (OR: 1.034; P = 0.029). No clear association was found in patients with a primary tumor size ≤1 cm (OR: 1.007; P = 0.570). The association between BMI and the BRAFV600E mutation status differs depending on the primary tumor size.
Competences for the future (Future Work 4S) – Green skills and environmental education
Authors: Nováková Daniela , Němejc Karel
Published: August 2024

This article describes an innovative Future Work 4S project and provides comprehensive feedback on a free Massive Open Online Course (MOOC) focused on environmental skills. Feedback was collected from two main target groups: educators (including university professors, teachers, and trainers) and student adult learners from Bulgaria, Greece, the Czech Republic, and Italy. The purpose of this survey is to provide an in-depth analysis of the feedback received on the Green Skills course and to highlight the main strengths identified by both educators and students. The findings reveal a high appreciation for the course’s interactive and experiential learning approach by both the students and the educators. Specifically, 93% of participants agreed that the course was interesting, engaging, relevant, accessible, and developmental. The course’s interactive exercises and gamification elements were particularly praised, enhancing learning and motivation. However, suggestions were made for including more practical examples and improving the uniformity of the text.
Прикладна хімічна наука для створення технологій вогнезахисту сталевих конструкцій
Authors: Вахітова Любов Миколаївна
Published: August 2024

Обговорено шляхи реалізації завдань прикладної тематики НАН України зі створення інноваційних технологій вогнезахисту сталевих конструкцій. Продемонстровано механізми втілення результатів фундаментальних досліджень у розроблення засобів пасивного вогнезахисту з подальшим впровадженням у промислове виробництво та застосуванням у будівельній галузі. Розглянуто фактори, що впливають на вогнезахисну ефективність реактивних покриттів: природа полімерної складової, співвідношення основних компонентів інтумесцентної системи, вміст і структура наноглин тощо. Запропоновано алгоритм прямих випробувань вогнезахисної ефективності в процесі розроблення рецептури інтумесцентного покриття. Отримані результати підтверджено повномасштабними вогневими випробуваннями. проведеними за європейськими та адаптованими національними стандартами.
Trends in HIE and Use of Hypothermia in California: Opportunities for Improvement
Authors: Bonifacio Sonia Lomeli , Liu Jessica , Lee Henry C. , Hintz Susan R. , Profit Jochen
Published: August 2024

BACKGROUND AND OBJECTIVES

Hypoxic-ischemic encephalopathy (HIE) is a leading cause of neonatal morbidity and mortality. Therapeutic hypothermia (TH), a proven treatment of moderate–severe HIE, was first used clinically after 2006. We describe trends in HIE diagnosis and use of TH over a 10-year period in California.

METHODS

We identified 62 888 infants, ≥36 weeks gestation, who were cared for in California Perinatal Quality Care Collaborative-participating NICUs between 2010 and 2019, and linked them to birth certificate data. We evaluated trends in HIE diagnosis and use of TH.

RESULTS

Over time, rates of HIE diagnosis increased from 0.6 to 1.7 per 1000 live births, and use of TH increased from 26.5 to 83.0 per 1000 infants. Rates of moderate HIE increased more than mild or severe, although use of TH for mild HIE increased more than for moderate. Of those with moderate–severe HIE, 25% remain untreated. Treatment varied by NICU level of care.

CONCLUSIONS

The rates of HIE and TH increased steadily. Some infants with moderate–severe HIE remain untreated, suggesting a need for ongoing education. Further evaluation of systems of care is needed to assure all qualifying infants are treated.
PERMODALAN, EFESIENSI, NON PERFORMING FINANCING, FINANCING TO DEPOSIT RATIO DAN PROFITABILITAS: BANK UMUM SYARIAH DI INDONESIA
Authors: KURNIA RAHMAT , FENITRA RAKOTOARISOA MAMINIRINA
Published: August 2024

Penelitian ini dilakukan dengan tujuan untuk mengetahui dan menganalisis pengaruh Permodalan (CAR), Efisiensi (BOPO), Non Performing Financing (NPF), dan Financing to Deposit Rasio (FDR) terhadap Profitabilitas Bank Umum Syariah di Indnesia periode 2018-2022. Jenis penelitian ini yang digunakan adalah deskriptif kuantitatif. Dengan menggunakan sampel di dalam penelitian sebanyak 10 Bank Umum Syariah. Pada penelitian ini menggunakan alat analisis regresi data panel dengan alat bantu aplikasi Eviews 12. Hasil uji yang didapatkan bahwa secara individu (Parsial) variabel Capital Adequecy Rasio (CAR) tidak berpengaruh secara signifikan terhadap Profitabilitas (ROA), Biaya Operasional Pendapatan Operasional (BOPO) tidak berpengaruh signifikan terhadap Profitabilitas (ROA), Non Performing Financing (NPF) tidak berpengaruh signifikan terhadap Profitabilitas (ROA), dan Financing to Deposit Rasio berpengaruh signifikan terhadap Profitabilitas (ROA).
Rural activity spaces integration with creative market models
Authors: Wu Mengyang
Published: August 2024

As urbanization advances and societal shifts unfold, the integration of rural development and activity spaces has become a focal point in academic discourse. This study aims to explore the synergistic effects of the creative market model on rural activity spaces, dissecting its role in shaping these spaces, enhancing community engagement, and generating socio-economic benefits. Empirical findings highlight the affirmative role of the creative market model in this fusion. The research on community participation and spatial design reveals how creative markets enhance residents' sense of involvement and explores the influence of activity space design on community interaction. This study, by thoroughly examining the integration of the creative market model and rural activity spaces, offers theoretical and empirical support for advancing rural development.
High urine sodium/potassium ratio, high LDL/HDL ratio, high level of serum F2-isoprostane, and low level of microtubule-associated protein 1a/1b-light chain 3b (LC3B) as risk factors of preeclampsia
Authors: Widiyanti Endang Sri , Kusuma Anak Agung Ngurah Jaya , Wande I Nyoman , Leonardi Monica , Wibawa I Gusti Ngurah Agung Satria
Published: August 2024

Background: Preeclampsia (PE), still a major health concern which is related to high maternal mortality and morbidity rates. It is historically correlated with early oxidative stress and autophagy dysfunction, prompting this study to investigate the potential risk factors of PE, including high level of urine sodium/potassium (Na/K) ratio, low-density lipoprotein to high-density lipoprotein (LDL/HDL) ratio, elevated serum F2-Isoprostane levels (F2-IsoPS), and diminished serum microtubule-associated protein 1a/1b-light chain 3b (LC3B).
Methods: This is a case-control study, conducted at Prof. Dr. I.G.N.G Ngoerah General Hospital from June to September 2023, including 25 pregnant women with preeclampsia (PE) as cases and 25 without PE as controls. The study analyses urine sodium and potassium levels, serum LDL and HDL levels, LC3B, and F2-isoprostane levels using the Enzyme-linked Immunoassay (ELISA) method. Statistical analysis was conducted using IBM SPSS Statistics Version 25 software.
Results: High urine sodium/potassium ratio (>3.95), high serum LDL/HDL Ratio (>2.6), high serum F2-Isoprostane levels (>476.24 ng/mL), and low serum LC3B levels (<291.975 ng.mL) was found to be a significant risk factor for preeclampsia, with an OR of 11.16 (p < 0.001; 95% CI = 2.86 – 43.46); OR= 23.222 (p < 0.001; 95% CI = 5.101 – 105.728); OR= 38.5 (p=0.000; 95% CI: 7.681-192.985); and OR=8.143 (p=0.001; 95% CI: 2.294-28.901) respectively. Based on multivariate analysis, the variables that contribute mainly to the occurrence of PE, from the highest, respectively, are high LDL/HDL ratio, high level of F2-IsoPs, low level of serum LC3B, and high urine Na/K ratio (OR=149.96; OR=95.43; OR=36.11; and OR=12.71).
Conclusion: High LDL/HDL ratio, high level of F2-Isoprostanes serum, low level of serum LC3B, and high urine Na/K ratio are risk factors for preeclampsia.
Unveiling the enigma: exploring the controversies of chordee pathophysiology and its treatment
Authors: Pitoyo Joko , Alvarino Alvarino , Darwin Eryanti , Yanwirasti Yanwirasti
Published: August 2024

Chordee, a congenital penile anomaly characterized by an abnormal downward curvature, presents a complex medical challenge due to its multifaceted etiology and varied treatment options. This comprehensive review delves into the intricacies of chordee, exploring its genetic, hormonal, anatomical, and environmental underpinnings. We examine the normal developmental processes of the penis, highlighting how deviations can lead to chordee and explain the role of genetic factors in its pathogenesis. The influence of hormonal factors, particularly androgens, in the development and morphology of the penis, and the impact of environmental endocrine-disrupting chemicals on penile development, are thoroughly analyzed. Treatment modalities for chordee range from surgical techniques to conservative management, each with its controversies and challenges. This review aims to provide a holistic understanding of chordee, offering insights into its complex pathophysiology and guiding clinicians in making informed decisions in patient care.
Marginal cord insertion in placenta and true knot in umbilical cord: a case report
Authors: Sanjaya I Nyoman Hariyasa , Mulyana Ryan Saktika , Pangkahila Evert Solomon
Published: August 2024

Background: The fetus and placenta are connected by the umbilical cord. Atypical cord attachment that occurs during pregnancy is called marginal cord insertion. However, placing the umbilical cord usually does not cause problems when a woman is pregnant. This study reported a case of marginal cord insertion in the placenta and a true knot in the umbilical cord.
Case Presentation: We reported a case of a 39-year-old pregnant woman who was found to have an umbilical cord attached to the edge of the placenta on ultrasound in a singleton pregnancy. The appearance of the umbilical cord insertion was at the edge of the placenta, and there is a true knot in the umbilical cord that was not diagnosed during pregnancy.The incidence of true umbilical cord knots has been found to range from 0.04% to 3%. They are linked to four times the risk of stillbirth and significant perinatal morbidity (11%) rates. A four-dimensional and color Doppler examination is essential to diagnose a real umbilical cord. A more thorough examination of the anomaly and repeated confirmation with power and color Dopplers are required for an accurate diagnosis.
Conclusion: We reported a case of a 39-year-old pregnant woman who was found to have an umbilical cord attached to the edge of the placenta on ultrasound in a singleton pregnancy. The appearance of the umbilical cord insertion is at the edge of the placenta, and there is a true knot in the umbilical cord that is not diagnosed during pregnancy.
Orofacial clefts patients epidemiology in Hermina Hospital during 2008-2017
Authors: Wardhana Aditya , Christabella W Rininta
Published: August 2024

Background: Malformation of lip and palate closure that occurs during embryology time in the mother's womb will affect the shape of mouth and face. This congenital malformation is often referred to orofacial clefts including cleft lip, cleft palate, cleft lip and palate. Orofacial clefts cases are still commonly found in Indonesia. This study aims to present orofacial clefts patients epidemiology in Hermina Hospital during 2008-2017.
Methods: Retrospective studies were conducted on 230 orofacial clefts patients at Hermina Podomoro and Hermina Kemayoran Hospital from 2008 until 2017. The variables include the distribution of age, gender, residency area, diagnosis, and type of operations.
Results: From 230 patients, there were 169 patients (73.5%) in age group of 0-4 years with an average 2.1 years old. 125 patients were male (54.34%). 103 patients from Jakarta (44.8%) and 127 patients from outside Jakarta (55.2%). There were 116 cases of cleft lip (50.5%), 99 cases of cleft palate (43%), and 15 cases of cleft lip and palate (6.5%). There were 137 labiaplasty operations (59.57%) and 93 palatoplasty operations (40.43%). Palatoplasty including primary and secondary palatoplasty.
Conclusion: Orofacials cleft patients from Hermina Kemayoran and Hermina Podomoro Hospital from 2008-2017 average age 2.1 years old. Most of the patients are male and came from outside Jakarta. The most common diagnosis is cleft lip with labiaplasty operation handling.
The role of methionine in tuberculosis and its potential clinical significance
Authors: Sari Putu Suwita , Mas Rizky A A Syamsunarno  , Chaidir Lidya
Published: August 2024

Tuberculosis (TB) remains a significant global health challenge. Multidrug-resistant tuberculosis (MDR-TB) holds a substantial health risk, and only a limited number of patients receive treatment for drug-resistant tuberculosis. Various studies have been conducted to address this condition, including through metabolic approaches to further understand the mechanisms of tuberculosis infection, one of which is methionine. There are various enzymes in the Mycobacterium tuberculosis (MTB) methionine biosynthesis pathway, the key enzymes such as MetX, MetC, MetE/MetH, MetK, MTHFR, and BCAT are essential in the biosynthesis of methionine, and hindering these enzyme activities may hold potential for new antitubercular drug development. Deletion of the metA gene weakens MTB, making it more prone to host immune responses. There is also the role of cobalamin, where cobalamin availability regulates the choice between metE and metH in methionine biosynthesis. Methionine plays a crucial role in bacterial protein translation and antioxidant activities. In bacteria including MTB, the initial methionine is formulated; this process involves several enzymes such as FMT, MetRS, PDF, and MetAP. Some compounds targeting MetAP have been identified to have significant inhibitory action against MTB, such as transitmycin and bengamides, and this also includes the drug resistant strain. Methionine supplementation alongside vitamin B-complex have shown to improve drug-induced toxicity in tuberculosis patients, this due to methionine serves as precursor to antioxidant glutathione. Metabolomics studies have shown that altered methionine levels in tuberculosis infection, with samples taken from human blood or urine show significantly lower levels in patients with active TB or failed treatment groups. This review aims to discuss the role of methionine in Mycobacterium tuberculosis and the progress of research targeting methionine metabolism and function.
Effect of anthocyanins on obesity
Authors: Surudarma I Wayan , Weta I Wayan , Wihandani Desak Made , Pinatih Gde Ngurah Indraguna
Published: August 2024

Obesity is a complex multifactorial disease characterized by excessive fat accumulation in the body. Obesity is caused by a chronic positive energy balance that is regulated by complex interactions between the endocrine and the central nervous system. The hypothalamus regulates energy balance by controlling appetite and satiety, regulating the rate of energy expenditure, and regulating hormone secretion. Leptin plays an important role in regulating appetite. Decreased leptin production or impaired receptor function in leptin resistance can increase the risk of obesity. Adiponectin plays an important role in peripheral stimulation to increase energy expenditure. Leptin and adiponectin have synergistic action to promote weight loss. The excessive increase in adipose tissue in obesity causes the secretion of pro-inflammatory cytokines. Pro-inflammation states can cause oxidative stress and chronic inflammation, which can disrupt the function of adipocyte cells in secreting leptin and adiponectin, which are important in the pathogenesis of obesity. Anthocyanins are flavonoid compounds that have been widely known as antioxidants and anti-inflammatory. Many studies have revealed that anthocyanins can also play an anti-obesity role. This review article will discuss the mechanism of action of anthocyanins as anti-obesity agents.
Distal radius reconstruction after Ewing’s sarcoma resection: An alternative of limb salvage procedure
Authors: Saputa Rhyan Darma , Kusuma Dita Anggara , Siswanto Totok
Published: August 2024

Background: Distal radius reconstruction after tumor resection is challenging due to hand structure and function complexity. The procedure has a high cost, causes donor morbidity, or sacrifices the joint motion. Treatment for Ewing’s Sarcoma in the distal radius involves radiation, surgery, and chemotherapy. Treatment of Ewing’s Sarcoma post neoadjuvant chemotherapy of the distal radius involves en bloc excision and distal radius reconstruction using lateral mass polyaxial screw and rod.
Case: A 38-year-old woman has a chief complaint of a lump in her left wrist, which, two years prior to admission, is getting bigger. The core biopsy and pathological result show Ewing’s Sarcoma of the left distal radius. Then we treat the patient with neoadjuvant chemotherapy, en bloc excision on the tumor, and distal radius reconstruction with lateral mass polyaxial screw and rod.
Conclusion: We hope to share our treatment experience in using the novel technique of lateral mass polyaxial screw in distal radius reconstruction can preserve the joint motion.
Our initial experiences with laparoscopic urologic surgery in a peripheral hospital in Central Java, Indonesia
Authors: Subekti Eko , Muchammad Fairuz Ali Nabil
Published: August 2024

Introduction: Nowadays, laparoscopic surgery in urology is widely adopted as a surgical technique for almost all cases, rendering the traditional open surgery approach obsolete. The increased use of laparoscopic surgical procedures has significantly contributed to progress in many urology areas. This study evaluates the initial experience with laparoscopic urology surgery in Banyumas General Hospital, a peripheral hospital in Indonesia.
Method: Between May 2023 and October 2023, laparoscopic urologic surgery was performed on 36 patients. The patient’s demographic characteristics, pre-operative diagnosis, type of laparoscopic approach, and intraoperative and post-treatment results were gathered and analyzed retrospectively.
Result: The mean patient age is 58.69±13.52 years, with 12 (33.33%) female patients and 24 (66.67%) male patients. While 20 had ureterolithotomy, 3 had pyelolithotomy, 5 had radical cystectomy, 2 patients received unroofing renal cyst, 1 had pyeloplasty, 1 had ureteral Anastomosis, and 1 had radical nephroureterectomy, 1 had a simple nephrectomy, 1 had diverticulectomy, and 1 had orchidopexy. 2 (5,56%) of the 36 patients must be converted to open surgery. The mean duration of surgery for procedures we did was as follows: ureterolithotomy 86.25 ± 7.23 minutes, pyelolithotomy 96.67 ± 7.64,  radical cystectomy 418± 64.09 min, unroofing renal cyst 57.5 ± 10.61 minutes, pyeloplasty 130 minutes, ureteral anastomosis 220 minutes, radical nephroureterectomy 210 minutes, simple nephrectomy 140 minutes, diverticulectomy 215 minutes, and orchidopexy 125 minutes. The mean hospital stay was 4.39 ± 2.28 (2-11) days. There are major complications, but no mortality was encountered.
Conclusion: Laparoscopic surgery is an effective technique with excellent outcomes, a safe and feasible alternative to open surgery in urology.
Effectivity of gambir extract (uncaria gambir roxb.) on the growth of bacteria staphylococcus aureus
Authors: Katu Hafsah , Syamsul Amirah R. , Rehatta Yongki  , Harun Achmad  , Sukarno Egita A.
Published: August 2024

Objective: This study aims to see the Minimum Inhibitory Concentration (MIC), minimum contact time of gambir extract, and the effectiveness of gambir extract (Uncaria gambir Roxb.) on the inhibition of growth of Staphylococcus aureus bacteria.
Material and Methods: This research is an experimental laboratory research. The research design used was the pre-test post-test control group. The samples used in the study were Staphylococcus aureus smear, gambir extract with the concentration of 2%, 4%, 6%, positive control (Chresophene), and negative control (aqubidest). Wilcoxon test and Mann Whitney test was used as the data analysis.
Results: The study showed that the Minimum Inhibitory Concentration of gambir extract at the concentration of 2% and the inhibitory of gambir extract at the concentration of 2%, 4%, 6%, and aquabides against the growth of Staphylococcus aureus bacteria with a diameter of the inhibitory zone formed around the disc paper was 6.46mm, 6.64mm, 7.16mm, and 5.60mm within 24 hours while 6.57mm, 6.95mm, 7.54mm, and 5.60mm was formed within 48 hours.
Conclusion: The MIC of gambir extract to Staphylococcus aureus is 2%, minimum contact time is 24 hours, and moderate inhibitory to Staphylococcus aureus bacteria.
Climate change and local identity extinction
Authors: Zaluchu Fotarisman
Published: August 2024

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Studi Komparasi Yuridis Hukum Sipil dan Hukum Gereja Katolik tentang Homoseksualitas
Authors: Ceha Marianus Nicandra
Published: August 2024

Tulisan ini bertujuan memberikan solusi untuk persoalan homoseksualitas dari sudut pandang Gereja Katolik. Homoseksualitas pada dasarnya merupakan suatu persoalan dalam hidup bernegara dan beragama. Persoalan ini mencakup tindakan-tindakan homoseksual dan pernikahan homoseksual. Peneliti menguraikan hal ini seturut hukum yang berlaku di Indonesia dan juga dalam paham Gereja Katolik. Peneliti mengemukakan tentang persoalan homoseksual dan pernikahan homoseksual dalam sudut pandang hukum positif di Indonesia dan hukum dalam Gereja Katolik. Hukum positif dan hukum Gereja Katolik menolak dengan tegas segala bentuk tindakan homoseksual dan pernikahan homoseksual. Pelanggaran terhadap ketentuan perundangan-undangan homoseksualitas dapat membuat seseorang atau sekelompok orang diberi sanksi pidana. Sedangkan Gereja menegaskan tindakan homoseksual merupakan sebuah pelanggaran moral yang adalah dosa. Dalam pandangan Gereja Katolik, kaum homoseksual tetap harus diterima martabatnya sebagai manusia. Martabat yang melekat dalam diri kaum homoseksual merupakan suatu hal yang mutlak dijaga dan diperjuangkan. Peneliti menguraikan hal-hal di atas dengan merujuk pada teks-teks yuridis hukum positif di Indonesia dan teks hukum dalam Gereja Katolik. Sumber-sumber lain digunakan untuk melengkapi penelitian ini. Penelitian ini dilakukan dengan metode komparasi teks yuridis hukum di Indonesia dan hukum Gereja Katolik. Pada bagian akhir penelitian ini, peneliti menawarkan solusi pemecahan persoalan homoseksualitas di Indonesia dari sudut pandang Gereja Katolik.
Peace Education: Philosophical Analysis and Review of Nonviolent Character Education Practices
Authors: Gultom Benediktus Hasiholan , Haq Mochamad Ziaul
Published: August 2024

This paper examines education with a modern philosophical analysis approach. From a phenomenological point of view, philosophy firmly shows that philosophy does not solely start from metaphysical conceptions but also always starts from contextual ones, which originate from actual or true events. The method of this writing is phenomenological based on developing thoughts about educational philosophy. From this literature review, the conclusion emerges that to overcome conflict with a non-violent mentality, education is believed to help humans develop a new mentality and character that allows humans to adapt to their social environment. Thus, in order for humans to comprehend one another and cultivate peace, they must be receptive to all possibilities within the framework of hermeneutics, including the historical background, which serves as the foundation. This paper contributes to a mindset that prioritizes openness to new ideas, remaining flexible and easy to adapt, change, and investigate routes that are rebuilt over time in accordance with the basic philosophy of humans as existentialist creatures.
Artificial Intelligence's Impact on the Development of Islamic Religious Education Learning at a Public Junior High School of Cilegon, Indonesia
Authors: Wasehudin Wasehudin , Aslihah Aslihah , Sirojudin Rumbang , Yuttana Yuttana
Published: August 2024

This study was conducted with the aim of knowing the existence of Artificial Intelligence (AI) in improving the quality of learning in Islamic Religious Education subjects. This study used a qualitative approach by using field observations and interviews to collect data. The research shows that educational institutions have felt the impact of technological advances and AI and have used these tools to improve the teaching and learning process. Education professionals recognize that these advancements are very beneficial in making the learning process more efficient and effective. Personalized learning, automated assessments, virtual tutoring, smart content, and presentation translation are some examples of the benefits of AI for education.
The Story of the Prophet Moses and the Pharaoh in the Qur'an: An Analysis of the Implementation of Structural Da'wah
Authors: Fadli Muhamad Aroka , Yunus Badruzzaman M. , Sarbini Ahmad , Kosasih Engkos
Published: August 2024

The story of Prophet Moses (Moses) and Pharaoh (Pharaoh) is the most frequently mentioned narrative in the Qur'an, appearing in as many as 296 verses. The repetition of this story underscores its significance and the lessons it holds, especially regarding relations with leaders. Scholars such as Sayyid Qutb, Hasan al-Banna, and al-Mawardi emphasize the obligation of Muslims to preach to unjust leaders using religious teachings. Allah warns of the dire consequences of a leader's injustice, including painful punishment and the destruction of a nation. Therefore, da'wah (preaching) to leaders becomes a crucial step. The research methodology includes collecting verses related to the story of Prophet Moses and Pharaoh, carefully examining the words and sentences used in these verses, studying the interpretations from various schools of thought, and conducting a thorough analysis using objective reasoning and philosophical and allegorical methods (ishari) as approached by al-Ghazali. The results of this study indicate that the implementation of da'wah from the story of Prophet Moses with Pharaoh is that despite numerous challenges from tyrannical regimes, Prophet Moses remained steadfast and patient in carrying out his ministry. Prophet Moses' style of discussion and reasoned debate demonstrates the value of a preaching strategy that focuses on both spiritual and intellectual strength. Prophet Moses' attitude demonstrates how a preacher must be courageous, patient, and consistent when dealing with opposing powers.
Geopolitics of Laos Renewable Energy and the Development of Water Energy for the Integrated Southeast Asia's Electricity
Authors: Indradipradana Ramaldy Krisna , Bevita Sari
Published: August 2024

This research explains the geopolitics of renewable energy from Laos as a country that has potential in water-based energy (hydropower) in the Southeast Asia region, with the main focus analyzing the mapping of the geopolitics of Laos renewable energy in the development of hydropower energy in Southeast Asia. The authors use the concept of Renewable Energy Geopolitics, which aims to map the geographic and technical characteristics of renewable energy systems and analyze energy relations between countries. The research method used is descriptive qualitative with literature study techniques in data collection. This research shows that Laos is taking advantage of competitive market conditions, thereby triggering investment in the water-based energy sector. Laos also focuses on producing water-based energy by implementing decentralization policies and community involvement in national development to minimize energy poverty, as well as organizing cooperation in technology to produce water-based energy with developed countries both from inside and outside the region.
Mitigating Climate Crisis: Integrating Climate Education into Educational System for Social Welfare Enhancement in Indonesia
Authors: Nugroho Leonyta , Muhammad Raafi
Published: August 2024

Indonesia still faces two significant challenges: a climate education system and relatively low social welfare rates. To address these pressing concerns, this study examines the feasibility of utilizing climate education to enhance social welfare. The study proposes a comprehensive framework for climate education in Indonesia using quantitative and qualitative research methods designed to adapt to various contexts, including formal educational settings such as schools and universities, while still accessible to underprivileged communities. The findings highlight the significance of integrating climate and environmental education into the educational system to prepare future generations to address ecological challenges. The paper also discusses the impact of the climate crisis on social welfare conditions in Indonesia, particularly for vulnerable communities. It proposes strategies for implementing climate education to enhance social welfare. It emphasizes the need for interactive and action-oriented approaches to climate education, as well as the role of universities in promoting practical solutions and student leadership. The framework presented in the paper aims to equip future professionals with the necessary tools and knowledge to drive innovation in sustainable technologies, shape responsible policy decisions, and foster community resilience.
Other Diagnostic Tests for Young-Onset Type 2 Diabetes Mellitus
Authors: Huamán Chavarry Katty Elizabeth , Pacco Valdivia Jorge Luis , Salvador Carrillo Andrea Elvira
Published: August 2024

We have read with interest the article entitled “A Cross-sectional Study to Evaluate Beta Cell Function in Individuals with Newly Diagnosed Young-Onset Type 2 Diabetes Mellitus and its Complications,”1 elevated C-peptide levels are indicative of both insulin resistance and beta cell malfunction. These factors are directly linked to the development of complications associated with young-onset Type 2 Diabetes Mellitus (YO-T2DM), including obesity, hypertension, and diabetic kidney disease. The present letter aims to expand the current diagnostic testing options for early detection of YO-T2DM.
Manajemen Pendidikan Islam di Era Internet of Things
Authors: Adnan Mohammad , Patsun Patsun
Published: August 2024

Laju peradaban manusia saat ini sudah tidak dapat dibendung lagi, kecanggihan teknologi sudah berkembang yang semula 1.0 saat ini sudah masuk era 4.0 yang telah menuntun kita pada satu keadaan dimana segala aspek kehidupan tidak dapat lagi berjalan secara manual. Kalau zaman dahulu segala bentuk pembelajan dan pengarsipan dilakukan secara manual, akan tetapi saat ini tidak lagi sama. Perkembangan teknologi telah mengantarkan kita pada satu konsep dimana proses pembelajaran dan pengarsipan data tidak lagi dilakukan secara manual, namun semuanya itu sudah dilakukan secara online, bisa menggunakan aplikasi apa saja dalam hal pembelajaran, maupun pengarsipan. Ditambah dengan adanya covid 19 yang terjadi maka semakin memaksa kita untuk menjadi bagian dari era internet, begitu juga dengan lembaga pendidikan Islam mau tidak mau harus melebur dalam era inernet.
Upaya Peningkatan Kemampuan Literasi Digital melalui Pengenalan Lingkungan Persekolahan (PLP) Mahasiswa Program Studi Pendidikan Agama Islam Fakultas Tarbiyah dan Keguruan Universitas Islam Negeri Sunan Ampel Surabaya
Authors: Moh. Faizin Moh. Faizin , Yudi Usman , Zainiyati Husniyatus Salamah
Published: August 2024

Pembekalan keterampilan literasi digital tentang kemampuan menggunakan teknologi dan informasi dari perangkat digital secara efektif dan efisien dalam pembelajaran di sekolah diajarkan dalam PLP 1. Literasi digital dalam aspek penciptaan dan penulisan pengetahuan baru ditingkatkan. dan menjadi kewajiban mahasiswa selama PLP 2 dibuktikan dengan penyerahan artikel pada jurnal yang diakui secara nasional. Hal ini juga sesuai dengan persyaratan penerbitan artikel ilmiah yang ditetapkan dalam keputusan Dikti. Diharapkan melalui penelitian ini akan terjadi sinergi antara mahasiswa dan pengambil kebijakan terhadap kurikulum PAI, jurusan keguruan dan tarbiyah UIN Sunan Ampel Surabaya dengan tujuan untuk mendukung program literasi digital yang diambil alih oleh pemerintah. Penelitian ini termasuk dalam penelitian kualitatif studi kasus (case study) yang dilakukan pada mahasiswa kurikulum PAI, tarbiyah dan jurusan keguruan UIN Sunan Ampel Surabaya. Kajian ini diawali dengan review literatur tarbiyah UIN Sunan Ampel Surabaya dan kebijakan fakultas keguruan terkait literasi digital melalui program PLP. Kajian ini merupakan upaya mencari titik temu kegiatan di lapangan terkait upaya literasi digital melalui Program Pengenalan Lingkungan Sekolah (PLP) untuk Anak mahasiswa di PAI Fakultas Tarbiyah dan keguruan UIN Sunan Ampel Surabaya. Analisis kebijakan dilakukan untuk menentukan dan mengkorelasikan tujuan dan cara untuk mencapainya. Pengembangan konsep literasi digital melalui program Pengenalan Lingkungan Sekolah (PLP) harus dilakukan untuk mengetahui diagram alir program PLP 1 dan PLP 2 Evaluasi kinerja dilakukan dengan tiga cara, yaitu: Pertama, Pre-test dan post-test bagi siswa PAI peserta Program Pengenalan Lingkungan Sekolah (PLP). Kedua, Persentase pencapaian kewajiban setiap mahasiswa untuk mengirimkan makalah hasil penelitian lapangan pada jurnal yang diakui secara nasional. Ketiga,Persentase makalah siswa yang memenuhi syarat untuk dipublikasikan di jurnal yang diakui secara nasional. Untuk menjaga keunikan penelitian ini, harus dilakukan tanpa campur tangan dari pihak tarbiyah dan keguruan UINSA, pengawas PLP, dan mahasiswa program PLP yang langsung melibatkan keluarga.
Upaya Guru dalam Melatihkan Kedisiplinan Ibadah Siswa di MIS Bidayatul Hidayah 3 Medan Amplas
Authors: Harahap Nur Saida , Matsum Hasan
Published: August 2024

The background of this study is the lack of self-awareness of students in worship discipline. This study aims to determine the efforts of fiqh teachers in training student worship discipline at MIS Bidayatul Hidaysh 3 Medan Amplas which includes the efforts of fiqh teachers to become uswatun hasanah, providing advice, punishments and rewards, training or practice and habituation as well as to find out the supporting factors and inhibiting factors of fiqh teachers' efforts in training worship discipline consisting of internal factors,  namely awareness, interests, motivations, and mindsets, and external factors, namely habituation, parental example, school environment, and friends. This research uses a type of field research with a qualitative approach. The subject in this study was 1 teacher of jurisprudence subjects MIS Bidayatul Hidayah 3 Medan Amplas, while the object of this study was the efforts of fiqh teachers, supporting factors and inhibiting factors of fiqh teachers' efforts in training student worship discipline at MIS Bidayatul Hidayah 3 Medan Amplas. Data collection techniques are taken by observation, interviews and documentation. After the data is collected, it is then processed through data reduction, data presentation, and conclusions. Based on the results of the study, the efforts of jurisprudence teachers in training student worship discipline in Mis Bidayatul Hidayah 3 Medan Amplas are to be uswatun hasanah or good role models for students, provide advice on the importance of worship discipline, provide punishment for students who are not disciplined and give rewards to students who are disciplined in carrying out prayers. In addition, jurisprudence teachers also continue to conduct trainings and practices by continuing to be supervised so that students are accustomed to discipline in carrying out worship.
Rahn (Gadai) dalam Perspektif Fikih Muamalah, Kompilasi Hukum Ekonomi Syariah (KHES), dan Hukum Perdata
Authors: Junitama Calvin Alief , Rahmawati Elvira Dwi , Karina Murtila
Published: August 2024

Pawn in Islam is called rahn. Pawning is an activity to pawn goods as collateral for a debt transaction carried out. A person who mortgages an item (rahin) to a murtahin person, then the item remains the property of the guarantor (rahin). As a result, a guarantor (murtahin) may not use or sell the collateral before obtaining permission from the guarantor. As for a murtahin, he can ask for money from the rahin if it is used for the maintenance of the rahin's property if maintenance is needed on the item. In this day and age, this pawn has become one of  the  solutions  to  the  urgent  need  for  money  which  is  needed  by  the  community.  In muamalah fikih and KHES, the pawn is called rahn. While in civil law the pawn is called a pand.
Inovasi Pemberdayaan Industri Kreatif Nasional sebagai Upaya Pemulihan Perekonomian Nasional Ditinjau Berdasarkan Konsep Pentahelix
Authors: Medlimo Rodrikson Alpian
Published: August 2024

This study explains the pentahelix concept as a government synergy with various actors in developing innovations to empower the national creative industry to be an essential thing to implement massively in Indonesia, especially after the Covid-19 pandemic hit. The recovery of the national economy based on the pentahelix concept is a reference for the government's seriousness in alleviating the problem of social inequality. The increasing number of gaps during the Covid-19 pandemic is a challenge and a reality that the Indonesian people must face. The increase in the number of holes is exacerbated by the condition of the Indonesian people, who need more creativity and innovation, which in turn gives birth to low-quality human resources. Pentahelix terminology must touch holistically and be carried out consistently and continuously as a government work program. Therefore, the involvement of various parties is the key to recovering the national economy, especially after the Covid-19 pandemic.
Efektivitas Program Penanganan Covid-19 dan Pemulihan Ekonomi Nasional (PC-PEN) ditinjau dari Ekonomi Pancasila
Authors: Rachel Francesca , Hanifa Shafa Andien , Akbar Wafa Raniah Putri
Published: August 2024

The COVID-19 Pandemic that has lasted for 2 years has resulted in a weakening of the economy in Indonesia. The formation of various policy strategies by the Government to overcome these conditions has been carried out based on the values espoused in the Pancasila Economic System. This system is expected to provide solutions in dealing with challenges and conditions during the pandemic. This solution is realized in extraordinary steps, one of which is the Economic Recovery and Structural Reform which is in line with the Covid Handling and National Economic Recovery (PC-PEN) program. The theme of the Government Work Plan (RKP) in 2022 is Economic Recovery and Structural Reform which is in line with the PC-PEN program which has been ongoing since 2020. Based on Law No. 2 of 2020 concerning Stipulation of Perppu No. 1 of 2020 concerning State Finance Policy and Financial System Stability for Handling the Covid19 Pandemic and/or in Facing Threats That Endanger the National Economy and/or Financial System Stability Becomes Law, with the focus on the budget for the PC-PEN program as a form of economic recovery, widening the APBN deficit above 3 percent of GDP is allowed until 2022. The government through the fiscal and monetary authorities prepares strategic steps for a soft landing and exit strategy in financing the national economic recovery based on people's welfare. This writing was made with a qualitative approach that aims to analyze the effectiveness of the Covid-19 Handling and National Economic Recovery (PC-PEN) program after the COVID-19 Pandemic by referring to the Pancasila values.
Kontrak Kerja dalam Hukum Bisnis Ketenagakerjaan: Analisis Perlindungan Hukum Hak dan Kewajiban Para Tenaga Kerja
Authors: Hanipah Aumalia , Dalimunthe Nikmah , Pertiwi Sri Indah , Sitompul Humaidi
Published: August 2024

Many workers in Indonesia experience violations of legal protection for their rights and obligations as workers, which is based on their ignorance of what a work contract is and what rights and obligations workers have. This forms the basis of this research, with the aim of analyzing employment contracts in the field of labor law: an analysis of the legal protection of workers' rights and obligations. The data analysis in this research uses qualitative methodology with a descriptive research design. Furthermore, this study reveals that labor law will always be related to the protection of workers' rights and obligations. In the field of labor law, an employment contract is defined as a written agreement between an employee and an employer that regulates various aspects of their working relationship. This contract serves as a legal framework that protects the rights and obligations between both parties. Legal protection is an effort to safeguard the dignity and human rights of legal subjects in accordance with applicable laws and regulations, whether in the form of policies or rules that can protect something from other threats. Rights and responsibilities between parties are interrelated, where one party's rights imply obligations for the other party.