bluuebunny/crossref_metadata_2025 huggingface dataset:
Praxisprofile als mixed-methods Ansatz zur Analyse performativer Öffentlichkeiten: Vorschlag für eine relationale Journalismusforschung
Authors: Reißmann Wolfgang , Siemon Miriam , Lünenborg Margreth , Raetzsch Christoph
Published: June 2022

Der vorliegende Artikel begründet und präsentiert einen mixed-methods Ansatz als Beitrag zu einer relationalen Journalismus- forschung. Ziel des Ansatzes ist es, die Herstellung von Öffentlichkeit in digitalen Medienumgebungen als geteilte Herstellungsleistung heterogener Akteur:innengruppen nachzuvollziehen und dabei gruppenspezifisch performativ-dramaturgische Stilmerkmale herauszuarbeiten. Zugrunde liegt ein praxeologischer Zugang, der für eine relationale Journalismus-forschung «beyond the newsroom» weiterentwickelt wird. Die Kontingenz, Vielstimmigkeit und Unübersichtlichkeit digitaler Öffentlichkeiten macht es notwendig, die traditionell mikrosoziologischen Vorgehensweisen in diesem Bereich zu verbinden mit quantitativen Netzwerkanalysen und standardisierten Akteur:innen- und Praxisanalysen. Hierfür wird ein dreistufiger Ansatz vorgestellt, der schrittweise durch quantitative und qualitative Methoden die Erstellung von «Praxisprofilen» einzelner Akteur:innen wie auch -gruppen erlaubt. Mit diesem interdisziplinären wie methodisch innovativen Ansatz soll Wandel in Öffentlichkeiten und im Journalismus auch komparativ verstehbar werden. Exemplarisch zeigen wir anhand erster Befunde zum Hashtag #systemrelevant, wie eine solche Analyse aufgebaut ist.
This paper develops and presents a mixed-methods approach as a contribution to relational journalism studies. The approach aims to retrace the making of publics in digital media environments through the performative contributions of heterogeneous groups of actors and to elaborate group-specific stylistic features of their communication. It is based on a praxeological approach that is further developed for relational journalism studies “beyond the newsroom.” The contin- gency, polyphony and complexity of digital publics makes it necessary to combine traditional micro-sociological approaches in this field with quantitative network analyses and standardized analyses of actors and their practices. For this purpose, a three-stage approach is presented, which allows for the sequential development of “practice profiles” for individual actors as well as groups of actors through mixed quantitative and qualitative methods. With this interdisciplinary and methodologically innovative approach, the change of public spheres and journalism can be understood comparatively. Using the hashtag #systemrelevant as an example, we show how such an analysis is structured.
Characterization of preoperative cardiovascular status and association with outcome following feline renal allograft transplantation: 166 cases
Authors: Aronson Lillian , Phillips Heidi , Oyama Mark
Published: June 2022

OBJECTIVES

To retrospectively evaluate preoperative historical, biochemical, and cardiovascular screening data for predictors of survival to discharge and long-term survival in feline renal allograft recipients from 1 institution.

ANIMALS

166 cats that underwent renal transplantation at the University of Pennsylvania between 1998 and 2018.

PROCEDURES

Medical records were reviewed for preoperative historical information, biochemical data, and cardiac assessment including auscultation findings, pre- and postoperative systolic blood pressure measurements, thoracic radiographic evaluation, and echocardiographic measurements. The need for hemodialysis, the number of surgical procedures, native kidney biopsy diagnosis and survival time was also recorded. Kaplan-Meier analysis was used to generate survival plots and estimate median survival times with a 95% CI. Univariable and multivariable analysis were performed to determine variables that were independently associated with survival to discharge and long-term survival.

RESULTS

The patient population primarily consisted of adult male DSH cats (70%) diagnosed with IRIS stage 4 CKD (66.3%). Abnormalities identified on preoperative cardiac assessment, including hypertension, the presence of a murmur, echocardiographic changes, and radiographic signs of congestive heart failure, were not associated with survival to discharge or long-term survival. Age was the only single significant variable associated with survival, and the risk of death increased by 11% (95% CI, 6% to 17%) for every 1 year in patient age.

CLINICAL RELEVANCE

The presence of cardiac abnormalities identified during the screening process of cats presenting for transplantation should not immediately exclude a potential candidate for the procedure. Owners considering transplantation should be educated on the impact of age on survival following surgery.
Analysis and prediction of second-hand house price based on random forest
Authors: Zhang Yan , Huang Jingru , Zhang Jiahui , Liu Shuying , Shorman Samer
Published: June 2022

Using Python language and combined with data analysis and mining technology, the authors capture and clean the housing source data of second-hand houses in Chengdu from Beike Network, and visually analyse the cleaned data. Then, a Random Forest (RF) model is established for 38,363 data elements. According to the visual analysis results, the model variables are revalued, the key factors affecting house prices are studied and the optimised model is used to predict house prices. The experiment shows that the deviation between the house price predicted by the RF model and that predicted by the real house price is small; it also indicates the accuracy of the RF model and demonstrates its good application value.
The Effect of Value Co-Creation on Behavioural Intention and Satisfaction with Tourism Resources in Lagos State, Nigeria
Authors: Tunde-Ajayi Olalekan A.
Published: June 2022

This study aimed to investigate the sociodemographic characteristics, travel characteristics and the effect of value co-creation on behavioural intention and satisfaction of visitors in Lagos state, Nigeria. Data was obtained by administering a questionnaire to 384 visitors; data was analysed and presented descriptively using tables and inferentially using Spearman correlation, logistic regression, T-test and ANOVA. Results revealed that there were more males and youthful visitors at the sites who were first-time visitors and who travelled primarily with their family. Furthermore, there were more active participants in site activities at the site and their involvement in value co-creation had an impact on their behavioural intention and satisfaction with tourism resources at the site. Value co-creation activities that would encourage visitors’ active participation at tourism destinations should be provided to improve visitors’ satisfaction, as visitors now tend to be part-producer in their experience rather than mere consumers.
Tourism Impact Dimensions, Residents’ Quality of Life and Support for Tourism in Hunza Valley, Pakistan
Authors: Khan Zaibunnisa , Masood Fazeelat , Khan Mubashir Ali
Published: June 2022

Tourism is one of the substantially growing economic sectors in the Hunza valley of Pakistan. This tourism growth is attributable to factors that not only shape residents’ quality of life but also their tourism support. This paper posits that residents’ perception of tourism impact dimensions (social, economic, environmental, and cultural) influences residents’ quality of life, which in turn affects their support for tourism in the valley. The empirical analysis of data collected from 561 respondents shows social, economic, and cultural dimensions of tourism as significant positive predictors of residents’ quality of life. In turn, quality of life partially mediates tourism impact (economic, social, and cultural) on residents’ support for tourism. The paper also discusses practical implications and research limitations.
Model of Quality Management Systems adoption in the hotel industry: A case study of hotels in Zimbabwe
Authors: Basera Vitalis , Mwenje Judy
Published: June 2022

The article is the construction of a model of quality management system (QMS) adoption in the hotel industry grounded on a case study of multiple hotels in Zimbabwe. QMSs in the hotel industry are adopted to guarantee that certain levels of quality required by customers are achieved. Achievement of certain levels of quality can result in better customer satisfaction, which is important to ensure sustainable operations for hotels. The study was concerned with the late adoption of QMSs in the hotel industry due to a number of internal and external factors. This study is an extract from a PhD project, which investigates external and internal factors affecting QMS adoption in hotel industry. To attain the objectives, interviews were conducted with hotel managers and key stakeholders, while focus groups were conducted with hotel staff to outline the factors affecting the adoption of QMSs and to get general enablers for adopting these systems. Directed content analysis and NVivo 12 were used to analyse data. The Eisenhardt's Model of developing theory from case studies was used. The study draws upon QMSs from 1970s to 2020s. The main factors affecting adoption of QMSs were established and their interrelatedness established. The BASERA-MWENJE model of QMS adoption was developed. The model has not been tested, besides some parts of it, during work. Model differences and similarities were identified from literature to fortify the BASERA-MWENJE model of QMSs adoption. This model will be offered to the hotel industry and other industries in general to simplify and improve the adoption of QMSs under Zimbabwe's National Development Strategy 1 (NDS) to realise Vision 2030 ‘Towards a Prosperous and Empowered Upper Middle-Income Society’.
Technology Induction in Education During COVID-19 is Recreation or a Curse?: Integration of Technological and Behavioral Factors from the Students’ Perspective
Authors: Khan Muhammad Rahies , Siddiqui Faiza , Khan Mubashir Ali , Rasool Yasir
Published: June 2022

The current study attempts to identify and measure the role of technology induction during the COVID-19 pandemic as either recreation or curse in students’ learning. By integrating the technology acceptance model (TAM) and innovation diffusion theory (IDT) the study tries to measure the student’s online learning experience as recreation or curse. Data was collected from 387 students through purposive sampling. The findings of the study confirm that introduction of technology in online learning plays a recreational and significant role in student’s online learning. However, computer self-efficacy and relative advantage were found to be a curse in online learning during the pandemic. The overall findings of the study imply that the shift of student’s learning from traditional to online learning has been through introduction of new technology and innovations, although the diffusion of innovation and technology among Pakistani students has been challenging because of a comparatively lower computer literacy level. The usefulness and ease of online learning have been the strongest predictive and recreational aspects in students’ online learning. Institutes and higher education commissions should further invest in enhancing the quality and effectiveness of these factors to improve the overall learning outcome of students through recreational technological induction in education.
The constitutional reform of the Judicial Council in the Slovak
Republic from the European comparative context
Authors: FARKAŠOVÁ Simona
Published: June 2022

This contribution responds to the so-called judicial amendment to the Constitution
of the Slovak Republic of 9 December 2020, which was published in the Collection of Law
No. 422/2020, which resulted, inter alia, in major changes of the position, composition, and
powers of the Judicial Council of the SR; the author points to the evolution of the Slovak
Judicial Council since 2001 as well as summarizes the circumstances that led to its
establishment, also changes in its constitutional status, composition, presidency, and
competencies. The contribution includes concrete details how, according to recent
constitutional reform, the system of checks and balances in the composition of the Judicial
Council of the Slovak republic was implemented, to eliminate the judicial corporatism and
negative consequences of political influence on that matter. The essential part of this
document is the comparative analysis of the selected aspects of the composition of judicial
councils in the selected European states. Special attention is paid to the issue of the majority
of the judges among other members and the influence of the political forces in the process of
selecting the members of the judicial councils. All of these used methods of scientific research
led the author to formulate and identify the system of checks and balances in the composition
of the judicial councils to ensure the independence and effectiveness of the judicial council
and even for the whole judiciary in a national and/or European environment.
Same aims, different pathways - deconcentrated state administration
in Croatia and Hungary
Authors: LOPIŽIĆ Iva , BARTA Attila
Published: June 2022

30 years after the beginning of democratic transition, deconcentrated state
administration (DSA) in Croatia and Hungary stands on different pathways - one led to the
abolition of county state administration offices and extensive fragmentation of DSA, the other
led to the integration of DSA and transforming county government offices to one of the
biggest first-instance state administration bodies in Europe. The paper compares
developmental paths of Croatian and Hungarian DSA during this period putting it into
broader institutional context of changes in local self-government system. The comparation
of Croatian and Hungarian case explores the interplay of historical heritage, pressures from
international and EU environment, and national specificities on shaping contemporary
territorial administration systems, role that DSA plays in post-socialist countries, and the
factors that dictate its developmental changes, roles, and significance in territorial
administration system.
Features of ensuring the rights of drug addicts for rehabilitation
in Ukraine and the European Union: comparative legal aspect
Authors: SHEVCHUK Oleкsandr , SHEVCHUK Viktor , KOMPANIIETS Ihor , LUKASHEVYCH Serhii , TKACHOVA Olena
Published: June 2022

This article explores the problems of legal regulation of the implementation of the
"right of drug addicts for rehabilitation" in Ukraine‚ and the foreign experience of individual
EU countries in this area. The methodology of this scientific work is based on the system of
methods of general scientific and special-legal methods of cognition. This paper reveals the
features of the implementation of the "right of drug addicts to rehabilitation", establishes the
concept of "rehabilitation of drug addicts", as well as the term "right of drug addicts to
rehabilitation", the legal status of individual subjects is studied. Who are involved in the
implementation of rehabilitation services for drug addicts. It is proposed to divide legal acts
that cover the implementation of the “right of drug addicts to rehabilitation” into two groups:
(1) general and (2) special. It is emphasized that the legal framework that would cover an
effective state system for the rehabilitation of drug addicts in Ukraine has not yet been
created, and as a result, a large number of drug addicts do not have access to rehabilitation
services‚ or do not receive them at all. Directions for optimizing the legislation of Ukraine
on the rehabilitation of drug addicts are given, with an emphasis on the implementation in
practice of effective programs for the rehabilitation of adolescents who are dependent on
psychoactive substances, taking into account their age groups. It is proposed to adopt a
special Law of Ukraine on the rehabilitation of drug addicts. It is concluded that the effective
implementation of advanced methods for the rehabilitation of drug addicts in Ukraine, taking
into account international standards, should be a priority part of state policy, and it is
important to use the principle of a holistic approach to the legal regulation of such
rehabilitation assistance.
Nutrition and health claims on foods in the EU legislation
Authors: LAZÍKOVÁ Jarmila , RUMANOVSKÁ Ľubica
Published: June 2022

The main aim of the EU food legislation is health protection of consumers. The key
regulations, Regulation 1169/2011 on food information to consumers and regulation on
nutrition and health claims are intended to ensure that consumers have sufficient information
about the quality of the food product. That is why there is an effort by the EU to constantly
improve food legislation in order to provide consumers with information in an acceptable
and useful form. Currently the nutrient profiles and botanical health claims are in the focus
of the EU Commission. However, this increases the requirements on food producers, in
particular on the packaging of the product, which must fit even more information in a
reasonably large font, and on the environment, as the amount of waste produced increases
with increasing packaging area. The paper deals with the selected legal arrangements
related to the health and nutrition claims on the food in EU food legislation in the context of
judgments of the Court of Justice of the EU and point out the actual questions in relation to
them.
Phraseological units as components of pun in advertising slogans (on the material of the German language)
Authors: Shubina E. L. , Semenova O. O.
Published: June 2022

The article examines mechanisms of building up puns in phraseological units in German advertising slogans. The online portal Slogan.de serves as the source for the language material and represents an extensive electronic database of slogans. The material of the electronic archive Slogan.de is presented on the examples from 35 economic branches. The aim of this study is to analyze the processes of building puns through the interaction of phraseological units within the pragmatic aspect of advertising texts, as well as the systematization of these processes. The relevance of the article is based on the fact that phraseological units are the object of special interest to linguists due to their variability. Phraseological units are also considered in this article in the paradigm of such a social and pragmatic phenomenon as the language of advertising. Advertising is designed to influence its recipient − to call for action, to convince, to waive objections. An advertising slogan has an even more specific purpose. Being a pragmatically oriented phenomenon, the slogan has its function to express the company’s philosophy as concise as possible, to evoke an emotional response and ensure its memorability. The slogan contains a complex of unique linguistic solutions and is mainly related with a deviation from the norm and building up a wordplay. Phraseological units also have a wide cognitive and linguapragmatic potential. They allow puns into their structure due to their variability. Methods of continuous sampling and semantic analysis were used. The paper analyzes and systematizes the main methods of constructing puns in phraseological units in their direct relationship with the extralinguistic context. The selected examples were divided into two main types of mechanisms: puns built up by changing the word and syntagma (at the phonetic, morphemic, lexical and syntactic levels) and puns built up without changing the word and syntagma. The paper states that a pun is closely related with the context of the advertising slogan and information about the product advertised.
The Effect Of Service Quality And Student Satisfaction On Student Loyalty
Authors: Lika Trisela  , Hermanto
Published: June 2022

Student loyalty is the most impotant part of measuring the reputation of a school.  This study aims to determine: (1) the effect of service quality on student satisfaction, (2) the effect of student satisfaction on student loyalty, and (3) the effect of service quality on student loyalty.  This study uses a survey quantitative approach.  It is conducted at Private High School in Kutoarjo District.  The sample of this research is 146 students.  Data collection techniques using is questionnaires. While data analysis using SmartPLS. The results of this study show that: (1) Service quality has positive and significant effect on student satisfaction, (2) Student satisfaction has positive and significant effect on student loyalty, and (3) Service quality has positive and significant effect on student loyalty.
Resilience To Negative Electronic Word Of Mouth: The Role Of Self-Congruity, Brand Attachment, And Prestige
Authors: Iha Haryani Hatta  , Supriyadi Thalib  , Harimurti Wulandjani
Published: June 2022

This study aims to: (1) introduce the concept of resilience to negative electronic word of mouth (eWOM); and (2) examine a process model from self-congruity, brand attachment, brand prestige, and resilience to negative eWOM using a moderation mediation model. A time-lag approach was conducted to collect data, involving 312 students from two universities in Jakarta. Moderation hierarchical regression using a macro process is used to test the hypothesis. The results show that resilience to negative eWOM can be strengthened through personal resources (self-congruity, brand attachment, and brand prestige). The brand attachment has been proven to be a vital factor that can strengthen resilience to negative eWOM, and this relationship becomes more robust as perceived brand prestige at a high level. These findings extend existing topics related to eWOM by presenting another form of consumer loyalty and trust in a brand through resilience to negative eWOM.
A QbD assisted modified release formulation of Midodrine Hydrochloride for management of long-term hypotension
Authors: Kheni Pratik , Mehta Dharmik
Published: June 2022

Midodrine Hydrochloride (MDH) is primarily utilized for the treatment of orthostatic hypotension. The main objective of this research work is to study the effect of the ratio of Methocel 4M to 100M, PVP K-30, and magnesium stearate in extended-release (ER) layer of bilayer tablets of MDH. Bilayer tablets of MDH were optimized by the design of experiment (DoE) using response surface face centre (α = 1), the central composite design having three independent variables at three levels. Bilayer tablets of MDH were administered once a day to reduce dosing frequency and improve patient compliance. Midodrine Hydrochloride tablets contain a drug layer and extended-release layer, which is further compressed into bilayer tablets. Based on the results of in-vitro %drug release it can be concluded that the ratio of Methocel 4M to 100M in MDH bilayer tablets shows a significant impact on % drug release whereas the concentration of PVP K-30 and concentration of magnesium stearate does not shows significant impact on % drug release. As the increase in the ratio of Methocel 4M to 100M, increase in the % drug release and as a decrease in the ratio of Methocel 4M to 100M, decrease in the % drug release. The optimized formulation of MDH bilayer tablets with 6% of Methocel 4M as an extended-release polymer, 24% of Methocel 100M as an extended-release polymer, 5% of PVP K-30 as a binder and 0.5% of magnesium stearate as a lubricant exhibits extended drug release up to 12 hours.
Buchanania lanzan fungal endophyte Penicillium sp. therapeutic properties attributed to lapachol in its extract
Authors: Sharon Jane , Shenoy Priyanka , Bhaskar Sneha , Kini Ramachandra , Sekhar Shailasree
Published: June 2022

Buchanania lanzan, Spr. (Family: Anacardiaceae) with known therapeutic potential is reported as vulnerable and is listed in Red Data Book of IUCN. With immense value for its bark, roots, seeds and gum, exploitation of the host on large scale is reported detrimental. Hence the authors have attempted to study the residing endophytes for metabolites equivalent to the host products. The leaf endophytic fungi were morphotyped based on internal transcribed spacer–deoxyribonucleic acid (ITS–DNA) sequences and B. lanzan endophytes identified by molecular typing include Penicillium sp, Fusarium sp., Aspergillus sp and Fusarium sp. Molecular typing identified Penicillium sp. as Penicillium gravinicasei with 98% similarity to the nearest genera and so its extract was screened for therapeutic capacities. Antioxidant activity of the extract exhibited 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging capacity with IC50 of 55.95 ± 3.29 μg.mL-1. Antimicrobial activity by disc diffusion in opposition to Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli and Bacillus subtilis significantly arrested bacterial growth. Bacterial biofilm inhibition capacity stained by acridine orange and ethidium bromide imaged by confocal laser scanning microscopy revealed bactericidal activity. Lapachol in the endophyte extract detected by TLC could support the therapeutic properties. Thus, studies on unexplored medicinal plant endophytes could pave path to identification of novel secondary metabolites as therapeutic agents and potential drug candidates.
Designing of heterocyclic compounds as promising VEGFR2 tyrosine kinase inhibitors: An Insilico analysis
Authors: Patil Ashwini , Baheti Kamalkishore , Pomaje Madan
Published: June 2022

Cancer is the most dangerous disease a human race battles with. Due to which, it is necessity of medicinal chemist to evaluate possible scenario to fight against this disease. The heterocyclic compounds has shown to possess intrinsic diversity and several physicochemical properties. Thus investigation of newer and potential compounds for their activity to resist several malignancies. The present study aims to derivatize four different heterocyclic compounds. The number of members present in the ring has importance in heterocyclic compounds. Thus the six-member ring containing pyrimidine, six-member ring fused with five member ring in indole, bi-penta membered ring containing thiadiazole and one six membered and a penta membered ring containing triazoles have been used in the present study. In the search of potential anti-cancer drugs, several molecules were evaluated and checked for their potency to interact with a cancer target enzyme Vascular endothelial growth factor receptor 2 (VEGFR2). This study involves detailed in-silico analysis of several compounds and indicates compounds having potential ability to resist this enzymes and hence the anti-cancer agent.
Evaluation of Anti-asthmatic Activity of Salvadora oleoids Leaves
Authors: Dahiya Rajshree , Vaghela Jai Singh
Published: June 2022

Salvadora oleoids (Family: Salvadoraceae) is being used in the traditional medicine for the treatment of severe bronchitis and asthma. So, the study aims to evaluate anti-asthmatic activity of S. oleoids leaves. Leaves are reported to contain flavonoids, saponins, steroids, alkaloids, and tannins, known to possess similar effects. Flavonoids have been shown to smooth muscle relaxant, bronchodilator, antioxidant, and anti-inflammatory activity. The flavonoids are also reported to inhibit mast cell degranulation. Saponins are reported to mast cell stabilizing, anti-allergic, anti-inflammatory and antihistaminic activity. Tannins are reported to inhibit cyclooxygenase (COX) enzyme, decrease vascular permeability and antioxidant activity. Steroids are reported to an extraordinarily strong anti-inflammatory activity by inhibiting cytokine release IL-1, 2 and 6. The present investigation was undertaken to evaluate the anti-asthmatic activity of ethanolic extract of S. oleoids leaves in experimental animals. Asthma is a chronic inflammatory disorder of the airways. Limitations of currently available therapies and associated side effects have created an urge to search new and better treatment options. Thus, present study was designed to evaluate anti-asthmatic activity of S. oleoids leaves. Ethanolic extract of S. oleoides was prepared and used in the dose of 200 mg/kg (p.o.). Various in-vivo models like histamine induced bronchoconstriction in guinea pigs and milk induced leukocytosis in mice were used for evaluating anti-asthmatic activity of the drugs. Ethanolic extract of S. oleoides showed a significant broncho-dilatory, anti-histaminic and anti-inflammatory activity. Thus, ethanolic extract of S. oleoides have significant anti-asthmatic activity. Thus, ethanolic extract of S. oleoides leaves have proved to be an effective drug in prevention of asthma.
Effects of pterostilbene isolated from Pterocarpus marsupium on high fat diet induced diabetic rats
Authors: GROVER BHAVNA , Roy Partha
Published: June 2022

Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action or both. The present study tested the anti-diabetic and hypolipidemic potential of pterostilbene isolated from Pterocarpus marsupium plants on high fat diet-induced diabetic rats. The high-fat diet-fed rats showed increased serum glucose, cholesterol, triglycerides and insulin resistance (p < 0.05). However, treating the animals with pterostilbene different biochemical parameters like glucose tolerance, glycogen content, glucose homeostatic enzymes like glucose-6-phosphatase and hexokinase, adipocytes differentiation, and the expression profiles of different genes regulating carbohydrate and lipid metabolism were improved significantly (p < 0.05). Further, pterostilbene was found to demonstrate dual regulation activities for peroxisome proliferators-activated receptors (PPAR) (both PPARα and PPARγ). In conclusion, these results show that pterostilbene acts as a potent anti-diabetic molecule. Hence further in-depth mechanistic studies are warranted to use this phytochemical as a medicine.
Anal extrusion of the ventriculoperitoneal derivation catheter: case report
Authors: Paes Larissa , Porto Maria Clara , Sousa Fernando , Barsam Fabiana , Bóscollo Adriana
Published: June 2022

OBJECTIVE: To report the case of extrusion of ventriculoperitoneal shunt (VPS) catheter in preschool children and demonstrate the rarity of this event. METHOD: Review of institutional electronic medical records. RESULTS: A 3-year and 7-month-old patient, who underwent VPS at birth due to hydrocephalus, was admitted to a health service with asymptomatic extrusion of the catheter through the anus. During evaluation, she presented painful palpation of the abdomen, but without signs of peritonitis, antibiotic therapy was started and later a joint surgical approach (pediatric surgery and neurosurgery) was performed to remove the VPS. The patient presented a good evolution with the proposed treatment. CONCLUSION: The most used treatment in hydrocephalus is VPS of cerebrospinal fluid. Although effective, its use presents complications such as poor insertion, obstruction, infection or migration of the terminal catheter. Cases with bowel perforation and anal extrusion of the distal shunt are rare and uncommon complications. The assessment and removal of the shunt should be performed quickly to avoid meningitis and ventriculitis due to pathogens in the gastrointestinal tract.
Endocrinological disorders in childrens and adolescents survivors of Hodgkin lymphoma
Authors: Bordin Luiza , Tormen Tiago , França Suzana
Published: June 2022

INTRODUCTION: Hodgkins lymphoma (HL) is one of the main malignancies among adolescents and young adults, but with a high survival rate. Endocrinological disorders are frequent in post-treatment patients, affecting up to 44% of these individuals. OBJECTIVES: To evaluate the endocrinopathies existing in patients undergone HL treatment in childhood and adolescence, to correlate these changes with the treatment characteristics and to propose an evaluation and follow-up protocol. METHODS: Retrospective longitudinal study, performed through medical records analysis, that evaluated children and adolescents aged 0-18 years, HL survivors, with initial treatment and minimum 3 years follow-up in a pediatric oncology service from 1990 and 2015. RESULTS: The sample consisted of 75 individuals with a mean age at diagnosis of 9.2 years and follow-up time of 8.6 years. All had undergone chemotherapy and 85.3% radiotherapy, with an average dose of 25.7Gy. Twelve individuals were excluded due to treatment abandonment or death. At least one endocrinological disorder was present in 20.6% of the patients, and 100% of them had thyroid dysfunction, with hypothyroidism being the most frequent. It was not possible to assess gonadal function, bone mass, glucose metabolism or dyslipidemia in the sample due to lack of data and short follow-up. CONCLUSION: The elaboration of a protocol of evaluation and follow-up of these patients is necessary for standardization of management and early diagnosis of comorbidities. Knowledge of the repercussions of treatment is essential to provide better quality of life for the survivor.
The challenges and strategies for breastfeeding in newborns with cleft lip and palate
Authors: Ville Ana Paula , Staszczak Leticia , Lopes Larissa , Vivan Jaine
Published: June 2022

OBJECTIVES: Review strategies that facilitate breastfeeding in children with cleft palate and cleft lip. METHODS: Narrative literature review carried out through online scientific bases. RESULTS: Cleft lip and palate are congenital malformations that hinder the breastfeeding process, interfering with sucking and swallowing, which can impair child development and the mother-baby bond. Breastfeeding should be encouraged, the baby’s sucking ability should be assessed, the breastfeeding should be properly demonstrated to parents, support for mothers to establish and maintain their milk supply, considering adaptive feeding equipment (specialized bottles and nipples) and education on the benefits of human milk. Even if there are factors that make breastfeeding impossible, the supply of human milk, through specialized bottles or other devices, should be encouraged, since there are nutrients that only it can offer to the newborn. Family education is an important part of successful breastfeeding and support should be started as soon as the cleft is diagnosed, during the prenatal and postnatal periods. CONCLUSION: Breastfeeding should be encouraged, and when it is not possible, breast milk should be offered. Early surgical repair (in the first two weeks of life) in simple cleft lip has increased BF rates and should be considered in services where availability is available. In addition, a support network for parents should be created, with health professionals, to provide guidance on the possibilities and success of breastfeeding, in addition to monitoring weight gain and hydration.
Event Sponsorship and Brand Loyalty: Mediating Role of Attitude Toward Sponsored Events and Sponsoring Brand
Authors: Toan Nguyen Dinh
Published: June 2022

This research is to investigate the impact of event sponsorship on consumers’ brand loyalty through attitudes toward sponsoring brand and sponsored event. Structural equation modelling (SEM) was conducted to test hypotheses with the survey data of 282 Vietnamese youth who have ever watched and followed the Rap Viet 2020 event. The findings indicated that congruity between event image and sponsoring brand image, self-congruity with sponsoring brand image, and attitude towards sponsored event had a significant positive effect on attitude towards sponsoring brand. Attitude towards sponsoring brand, self-congruity with sponsoring brand image, and self-congruity with event image had a significant positive effect on brand loyalty. Congruity between event image and sponsoring brand image, self-congruity with sponsoring brand image, and self-congruity with event image had a significant positive effect on sponsored event attitude. The congruity between event image and sponsoring brand image, self-congruity with sponsoring brand image influence sponsoring brand loyalty by mediating the effects of event attitude and sponsoring brand attitude. Self-congruity with event image influenced sponsoring brand loyalty by mediating event attitude and sponsoring brand attitude. Based on the research’s empirical analysis, some implications were proposed to help sponsor and sponsee managers on how to improve the effectiveness of sponsorship activities.
Diagnostic power of laboratory methods for assessing ulcerative colitis severity: A prospective comparative study
Authors: Bolotova E. V. , Yumukyan K. A. , Dudnikova A. V. , Gilevich I. V.
Published: June 2022

Background. The epidemiology of ulcerative colitis in the Russian Federation is typified by late diagnosis and the predominance of severe complications entailing high mortality.Objectives. A comparison of the diagnostic value of laboratory methods for assessing ulcerative colitis severity.Methods. A total of 178 ulcerative colitis patients were divided into 4 cohorts by the presence and severity of attack; a control cohort included 40 healthy volunteers. Besides standard tests, a cytokine profile was determined in all patients: IL-1 IL-2, IL-4, IL-6, IL-10, TNF-α, IL-17; faecal inflammation marker concentrations — lactoferrin (LF), calprotectin (CalP), neopterin (NP); optical anisotropy (OA) of neutrophilic granulocyte nuclei; clinical activity index (CAI); Mayo scores. A single-factor analysis of variance was performed to compare the diagnostic value of laboratory tests, with a Mayo score taken as the factor reflecting ulcerative colitis attack severity. Differences were assumed statistically significant at p < 0.05. Results. The patients suffering from ulcerative colitis exhibited statistically significant Mayo score correlations with IL-6 (r = 0.598, p = 0.001), IL-17 (r = 0.587, p = 0.005), TNF-α (r = 0.701, p = 0.001), CalP (r = 0.881, p = 0.001), LF (r = 0.799, p = 0.001), NP (r = 0.791, p = 0.001) and OA (r = –0.877, p = 0.001). Faecal inflammatory biomarkers varied in the range from 73.4 (NP) to 95.3% (CalP) of total variance. Serum markers varied from 75.2 (IL-6) to 88.1% (IL-17) of total variance. As of all markers, the highest diagnostic value was observed for CalP (95.3% of total variance), while the lowest — for NP (73.4% of total variance). In the analysis of variance, the cut-off values for serum markers in predicting endoscopically active disease (>1 Mayo score) comprised: IL-6 = 10.3 pg/mL; IL-17 = 18.5 pg/mL; TNF-α = 10.9 pg/mL. The analogous values for faecal markers were: CalP = 112.0 μg/g; LF = 80.9 μg/g; NP = 92.8 μg/g. Neutrophilic granulocytes optical anisotropy comprised 94.5% of total variance, which compares with CalP by diagnostic power.Conclusion. A high diagnostic power has been demonstrated for faecal inflammatory markers (calprotectin, neopterin, lactoferrin), cytokines (IL-6, IL-17, TNF-α) and neutrophilic granulocytes optical anisotropy in detecting the attack relapse and severity.
Forensic evaluation of cervical spine distortion injuries in non-fatal road traffic accidents: An observational study
Authors: Travenko E. N. , Porodenko V. A. , Anuprienko S. A. , Аshkhotov A. V. , Penkin A. S.
Published: June 2022

Background. The study relevance is substantiated by the growing numbers of road vehicles and cervical spine traumas occurring among all spinal injuries. Currently, there is no common vision of the cervical trauma pathogenesis, diagnostic algorithm or treatment, which stipulates difficulties in the forensic evaluation of soft tissue injuries of the neck, especially combined with the head or spine traumas around neck, as well as certain diseases.Objectives. A study of the incidence of cervical spine distortion injuries and their clinical and forensic assessment for severity to human health.Methods. A retrospective selective single-stage trial and analysis of 32 forensic medical reports on road accident and physical injury administrative cases in 2017 (single year) have been conducted. Normally distributed data are presented as mean (M), standard deviation (SD) and percent shares. The significance of inter-share variation was estimated with Student’s t-test.Results. Cervical spine distortion injuries more frequently associated with traumas to drivers than passengers inside the salon (81.2%), especially in passenger vehicles, with front-seat travellers inflicted most often (60.0%). Cases of independent pathology were very rare. The most common were combinations with soft tissue injuries, combined blunt trauma to the head, torso and limbs, with craniocerebral or maxillofacial trauma. Cervical osteochondrosis was revealed in 18% cases. Primary diagnosis predominantly grounded on complaints and history (67%), with only 12% cases using a comprehensive neurological examination or instrumental methods. The severity was assessed in the context of concomitant injuries. Acute and moderate severity had equal rates of 6.2%, light severity — 37.5%, no damage — 9.3%. Non-qualified remained 39.8% cases due to a lack of full clinical and instrumental examination (66.7%) or the victim’s failure to appear (13.3%); 20% cases were expert-reported as uncertain for trauma circumstances and mechanism.Conclusion. Further research and systematisation of the data accumulated are necessary. The following clinical and forensic evaluation, as well as statistical analyses will facilitate common diagnostic and severity assessment algorithms to develop for mechanical soft tissue and ligament injuries of the cervical spine.
PENINGKATAN KEMAMPUAN MENULIS PUISI SISWA KELAS V SDN SUMBERBENING 1 KECAMATAN BRINGIN KABUPATEN NGAWI MELALUI STRATEGI OBSERVASI LINGKUNGAN
Authors: Dwiarno Pradistya Arifah
Published: June 2022

Penelitian ini bertujuan untuk meningkatkan kemampuan menulis puisi siswa kelas V SDN Sumberbening 1 Kecamatan Bringin Kabupaten Ngawi. Hal tersebut dilakukan karena siswa kelas tersebut sangat kurang dalam hal menulis puisi terutama dalam hal judul, isi, dan diksi. Padahal kemampuan menulis terutama menulis puisi harus dimiliki sejak pendidikan dasar. Penelitian ini dilaksanakan selama 6 bulan yaitu menjadi 2 tahap. Sedangkan tempat penelitian bersifat terikat karena harus dilakukan di sekolah yang bersangkutan. Rancangan dalam penelitian ini adalah Penelitian Tindakan Kelas. Sumber data dalam penelitian ini adalah hasil penilaian dari kegiatan pembelajaran selama 2 siklus. Setelah penelitian dilaksanakan dalam 2 siklus, diperoleh hasil peningkatan dalam hasil belajar. Hasil pada siklus I belum mencapai batas minimal nilai. Barulah setelah siklus II peningkatan hasil belajar terlihat, yaitu dari sisi judul, isi, dan diksi. Siswapun lebih antusias jika menulis puisi dengan strategi observasi lingkungan
IMPLEMENTASI MODEL PEMBELAJARAN EXPERIENTALLEARNING UNTUK MENGEMBANGKAN KREATIVITAS SISWA DALAMMENCIPTAPUISI PADA SISWA KELASVIII DISMP NEGERI2 NGEBELTAHUN AJARAN 2017/2018
Authors: Yunidawati Silviana , Cahyono Bambang Eko Hari , Waraulia Asri Musandi
Published: June 2022

Penelitian ini bertujuan untuk: (1) mendeskripsikan pelaksanaan model pembelajaran experiential learning; (2) mendeskripsikan seberapa jauh keefektifan model pembelajaran experiential learning; (3) mendeskripsikan kendala-kendala apa saja yang dihadapi guru dan siswa, serta pemecahannya dalam menerapkan model pembelajaran experiential learning pada siswa kelas VIII A  di SMP Negeri 2 Ngebel. Penelitian ini merupakan penelitian deskriptif kualitatif.Data dan sumber data dalam penelitian ini adalah narasumber, peristiwa atau aktivitas, dokumen dan arsip.Instrumen yang digunakan dalam penelitian yaitu lembar observasi kemampuan guru dan siswa, pedoman wawancara, dan panduan observasi.Teknik pengumpulan data yang digunakan adalah observasi, wawancara, dan dokumen atau arsip.Teknik analisis data yang digunakan adalah reduksi data, penyajian data, dan verifikasi.Teknik keabsahan data yang digunakan adalah teknik trianggulasi sumber data dan triangulasi dengan metode. Dokumen dan arsip dalam penelitian ini yang digunakan adalah rencana pelaksanaan pembelajaran, silabus, hasil wawancara guru bahasa Indonesia dan juga hasil wawancara dengan siswa kelas VIII di dalam kelas.Hasil penelitian (1) penerapan model pembelajaran experiental learning dalam pembelajaran mencipta puisi berjalan dengan baik dan efesien sesuai dengan perencanaan pembelajaran yang dibuat oleh guru; (2) keefektifan penerapan model pembelajaran experiental learning dalam pembelajaran mencipta puisi berjalan dengan lancar; (3) terbatasnya waktu serta kurangnya inspirasi adalah kendala penerapan model experiental learning dalam pembelajaran mencipta puisi.
KUALITAS DAN KUANTITAS TULISAN ILMIAH MAHASISWA UNIVERSITAS PGRI MADIUN
Authors: Huda Muhammad Binur
Published: June 2022

Menulis sangat diperlukan mahasiswa khususnya menulis ilmiah untuk kepentingan akademik. Akan tetapi kemampuan mahasiswa dalam menulis ilmiah tergolong rendah. Hal ini disebabkan oleh beberapa faktor yaitu ketergantungan pada dosen di kelas, kurangnya berlatih menulis, rendahnya minat baca, dan penggunaan metode menulis yang tidak sesuai. Dampak dari rendahnya kemampuan menulis tentu saja pada sedikitnya artikel ilmiah yang dipublikasi pada jurnal nasional maupun internasional. Dengan demikian, perlu digalakkan gerakan literasi terlebih dulu lalu meningkatkan kualitas dan kuantitas tulisan ilmiah sehingga mendukung terwujudnya publikasi pada bebagai jurnal tersebut.
IMPLEMENTASI MODEL PENGEMBANGAN KREATIVITAS DALAM PEMBELAJARAN CERITA PENDEK
Authors: Cahyono Bambang Eko Hari , Sunarsih Dwi
Published: June 2022

Penelitian ini bertujuan untuk mendeskripsikan dan menjelaskan kondisi pembelajaran cerpen pada siswa MTs, implementasi model pengembangan kreativitas, dan kendala-kendala yang dihadapi guru dan siswa. Metode penelitian yang digunakan adalah metode deskriptif kualitatif. Sumber data berupa informan, peristiwa, dan dokumen. Informan dalam penelitian ini adalah guru Bahasa Indonesia dan siswa. Pengumpulan data dengan teknik wawancara mendalam, teknik observasi, dan studi dokumentasi. Analisis data dilakukan dengan model analisis interaktif, yang dilaksanakan dalam dua tahap, yaitu pada saat atau selama berlangsungnya pengumpulan data dan setelah pengumpulan data. Hasil penelitian menunjukkan: (1) pembelajaran cerpen berpusat pada guru dan bersifat teoretis, sehingga pengembangan aspek kreativitas sangat minim, (2) model pengembangan kreativitas mampu menciptakan suasana pembelajaran baru yang menyenangkan, mendorong pembelajaran lebih menarik, siswa lebih semangat dalam belajar, mendorong siswa berani mengemukakan pendapat, dapat melatih siswa untuk mengembangkan kreativitasnya melalui kegiatan berpikir kritis dan mencipta karya sastra, dan (3) kendala-kendala yang dihadapi oleh guru dan siswa dalam mengimplementasikan model pengembangan kreativitas dalam pembelajaran cerpen, yaitu  siswa kurang aktif dalam berdiskusi serta guru belum mampu menjadi fasilitator pembelajaran secara baik, pengetahuan siswa tentang cerpen dan kemampuan berbahasanya kurang baik, kemampuan siswa dalam menulis kreatif kurang baik.
PENDIDIKAN KARAKTER DALAM NOVEL ”BUMI CINTA” KARYA HABIBURRAHMAN EL SHIRAZY DAN IMPLEMENTASINYA UNTUK MATERI PEMBELAJARAN BAHASA INDONESIA DI SMKN 2 MADIUN KELAS X SEMESTER II
Authors: Faradela Nely Maurena , Suharto Teguh , Huda Muhammad Binur
Published: June 2022

Penelitian ini bertujuan untuk mendeskripsikan dan menjelaskan nilai-nilai pendidikan karakter dalam novel Bumi Cinta karya Habiburrahman El Shirazy dan implementasinya dalam pembelajaran bahasa Indonesia siswa kelas X SMKN 2 Madiun tahun pelajaran 2018/2019. Penelitian ini dilaksanakan mulai maret 2019 sampai Juni 2019 mulai dari menganalisis novel Bumi Cinta karya Habiburrahman El Shirazy dan implementasinya pada siswa kelas X OTKP 3 tahun pelajaran 2018/2019. Penelitian ini menggunakan penelitian deskriptif kualitatif, dengan informan siswa kelas X OTKP. Adapun hasil penelitian dari deskripsi nilai-nilai pendidikan karakter yang terdapat dalam novel Bumi Cinta karya Habiburrahman El Shirazy adalah: Religius, jujur, toleransi, disiplin, kerja keras, kreatif, mandiri,  demokratis, semangat kebangsaan danm nasionalisme, cinta tanah air, menghargai prestasi, komunikatif, cinta damai, gemar membaca, peduli lingkungan, peduli sosial, tanggung jawab, dan rasa ingin tahu.SMKN 2 Madiun tahun pelajaran 2018/2019 yaitu sebagai berikut. Dimulai dari kegiatan perencanaan pembelajaran yang isinya mulai dari pemilihan novel Bumi Cinta karya Habiburrahman El Shirazy, membahas RPP, pelaksanaan pembelajaran yaitu mengidentifikasikan unsur intrinsik dan nilai karakter yang ada di dalam novel, dan evaluasi pembelajaran.