bluuebunny/crossref_metadata_2025 huggingface dataset:
Influence of Climate Changes on Water Resources in Moldova
Authors: Ivanov Violeta
Published: May 2021

The paper aims to analyze the current state of affairs with water resources in Moldova, the challenges it faces for its national human and economic development, having in mind that the water resources are quite limited in Moldova, which encounters pollution, degradation influenced by climate change and unwise human activity to their biodiversity and ecosystems, availability and accessibility. It also attempts to highlight the relationship between climate change and water resources in Moldova, which has adverse effects on both environment and people’s health, and raise significant hurdles to the international, regional and sectoral development.
Silver Loaded Clay and Investigation of Their Antimicrobial Activity
Authors: Copcia Violeta Elena , Sandu Ion , Bilba Nicolae , Dunca Simona
Published: May 2021

To guarantee the microbiological quality of the water, which is been affected by the pollution of the bacterium, is necessary to implement a tertiary drinking system in the resident houses. A possible complementary system is the utilization of clay for treatment of drinking water.
The Pollution Spectrum of Old Pesticides Storages in Moldova
Authors: Duca Gh. , Bogdevich O. , Cadocinicov O. , Porubin D.
Published: May 2021

The inventory of old pesticide storages in Moldova executed by Ministry of Environment and World Bank showed a large quantity of polluted sites (near 1500) remains after the repacking and evacuation project. This work was made first of all for Persistent Organic Pollutants (POPs). More that 15 % sites were determined as extra high polluted territory with the POPs concentration in soil more 50,0 mg/kg. They include some of the world's most harmful chemicals including highly toxic pesticides such as HCH, DDT; industrial chemicals such as PCBs. The management of domestic and hazardous wastes is considered as one of the most urgent environmental problems in Moldova.
Trends of Current Dynamics of Chemical Processes in the Soils of Odessa Region
Authors: Bilanchyn Yaroslav , Rezvaya Svetlana , Medinets Sergiy , Pitsyk Vasiliy
Published: May 2021

Results of chemical processes’ dynamic studies of many years (1971-2011) in the soils of Odessa Region have been described. The most significant in the last 15-20 years have been changes of humus content and ecological & agrochemical status of black soils. In spite of some increase in the norm of fertilizers input for the last 5 years the negative balance of plant nutrition elements in soils is preserved. Ways of optimization of humus and ecological & agrochemical status of soils in the region and increase of their fertility have been proposed.
The Study of Cadmium Uptake by Water Hyacinth (Eichhornia Crassipes) Using a Natural Modelling Approach
Authors: Romanova Tamara E. , Belchenko Ludmila A. , Shuvaeva Olga V. , Kurbatova Maria V.
Published: May 2021

The results of the investigation on the accumulation of cadmium by water hyacinth, depending on the conditions of pollutant exposure and the presence of various additives are discussed. The main specialty of this study is that all the experiments were carried out in natural conditions using the approach based on the application of the capacities called minicosms. It allowed estimating hit consequences of pollutant on ecosystem most really having made experiment in the conditions as much as possible close to the natural. In this article a very important problem of an accuracy and reliability of the results of trace elements determination in plants is also debated. As a result of carried investigations it was shown that the degree of cadmium extraction by hyacinth from contaminated natural water while maintaining the viability of the plants depends on the way of pollutant introducing into the reservoir and the maximum (about 79%) value is observed in the case of it’s gradual entry.
Computer-Based Prediction of Toxicity Using the Electron-Conformational Method. Application to Fragrance Allergens and Other Environmental Pollutants
Authors: Gorinchoy Natalia N. , Bersuker Isaac B.
Published: May 2021

The electron-conformational (EC) method is employed for the toxicophore (Tph) identification and quantitative prediction of toxicity using the training set of 24 compounds that are considered as fragrance allergens. The values of a=LD50 in oral exposure of rats were chosen as a measure of toxicity. EC parameters are evaluated on the base of conformational analysis and ab initio electronic structure calculations (including solvent influence). The Tph consists of four sites which in this series of compounds are represented by three carbon and one oxygen atoms, but may be any other atoms that have the same electronic and geometric features within the tolerance limits. The regression model taking into consideration the Tph flexibility, anti-Tph shielding, and influence of out-of-Tph functional groups predicts well the experimental values of toxicity (R2 = 0.93) with a reasonable leaveone- out cross-validation.
Interaction of Albumin and Immunoglobulin G with Synthetic Hydroxyapatite
Authors: Pylypchuk E. , Mishchenko V. , Gromovoy T. Yu.
Published: May 2021

It was shown by X-ray phase analysis, IR spectra analysis and MALDI-ToF mass spectrometry methods that interaction of synthetic hydroxyapatite with a solution of immunoglobulin G leads to its partial dissolution due to leaching from the surface of calcium triphosphate which, in our opinion, forms complexes with immunoglobulin G.
A Reaction of 4, 5-Diphenylimidazole Nitration in the Presence of Some 3d-Metals Nitrates
Authors: Voda I. , Druta V. , Indricean C. , Ciumacov I. , Turta C.
Published: May 2021

By interaction of cobalt(II), nickel(II), or zinc(II) nitrate with 4,5- diphenylimidazole in methanol in solvotermal conditions the new derivative of imidazole (4,5-diphenyl-2-nitroimidazole) and three new coordinative compounds [M(4,5-Ph2ImNO2)2(CH3OH)2] have been synthesized and investigated. Metal ions have a distorted octahedral environment with N2O4. Coordination number of metal is six. Ligand is coordinated to metal ion by one oxygen atom of nitrogroup and one nitrogen atom of imidazole.
The Study of Chemical Composition and Evaluation of Groundwater Quality in Some Regions of Moldova
Authors: Mitina T. , Bondarenco N. , Bunciuc O.
Published: May 2021

The paper presents the results of groundwater study from different sources, selected in v. Myndreshty, Telenesti district, in various villages of Cahul district and in artesian wells in and around Chisinau. Large differences were evidenced in water chemistry in different villages of one district, as well as within the same village. Was assessed thee compliance of analyzed water to quality requirements of drinking water.
Selective Organic Synthesis for Sustainable Development
Authors: Macaev F.
Published: May 2021

The data on the development of selective organic synthesis suitable for obtaining multifunctional organic compounds both linear and cyclic structures using environmentally benign, inexpensive and renewable resources summarized. This article is an extended abstract of a communication presented at the Conference Ecological Chemistry 2012.
Hydrogen Molecule Interaction with CpCr(CO)3 Catalyst
Authors: Spataru T. , Fernandez F.
Published: May 2021

The hydrogen molecule interaction with CpCr(CO)3 catalyst has been studied using the B3LYP, B86 functionals and the 6-311++G**, LACV3P basis sets. The best results in the testing calculations of the analyzed reaction have been obtained by using the B86/6-311++G** DFT version giving quite good agreement between experimental and theoretical calculated enthalpies. The dispersion corrected DFT Grimme’s and Head-Gordon and coworkers’functionals have been attempted without any improvement of the results. The free energies of the initial reactants, transition states, intermediate compounds and fi nal products of the typical six-ring bond modifi cation mechanism have been calculated. The energy barriers of the reaction pathways are too high in the DFT approximation.
Pecularities of Phosphorus Forms Dynamics in Bottom Sediments of River Dniester (Moldova)
Authors: Rusu V. , Postolachi L. , Maftuleac A. , Lupascu T.
Published: May 2021

Seasonal, spatial and multi-annual dynamics of phosphorus forms in bottom sediments and their interstitial water for river Dniester was evaluated. The spatial dynamics of phosphorus forms in the bottom sediments along river had, in general, the same trend during of 2004 and 2009 years, being recorded the increasing tendency along river Dniester for inorganic phosphorus and decreasing tendency for organic phosphorus. Multi-annual dynamics for 2004-2010 years showed a tendency of increasing of all phosphorus forms in bottom sediments; the highest values being registered during 2010 year. Spatial and seasonal dynamics of phosphorus forms in bottom sediments and their interstitial water were generally in correspondence, although sometimes with some differences.
Imagens de estudantes na publicidade do ensino superior privado: marcadores sociais da diferença em articulação / Student images in private higher education advertising : social markers of the difference in articulation
Authors: Macedo Renata Mourão
Published: May 2021

Neste artigo, a partir de pesquisa de campo realizada entre 2015 e 2018 na cidade de São Paulo e em meio digital, analiso as relações entre mercado de ensino superior privado, publicidade e marcadores sociais da diferença (classe, raça e gênero, em especial). Se, historicamente, a publicidade brasileira privilegiou corpos brancos e estilos de vida associados à classe média, no período recente algumas transformações foram visíveis, incorporando perfis mais diversos de estudantes, incluindo várias peças publicitárias com protagonismo de jovens mulheres negras. Minha hipótese neste artigo é a de que tais transformações se relacionam, de um lado, com o fenômeno de maior acesso da “classe C” (conforme a linguagem do mercado) no ensino superior privado a partir de meados dos anos 2000. De outro lado, tais publicidades passaram a incorporar algumas das demandas de maior representatividade realizadas pelos movimentos negros e feministas. A incorporação de tais transformações visou tornar as peças publicitárias mais atrativas para um novo público consumidor de diplomas universitários no Brasil.Palavras-chave: ensino superior privado, publicidade, marcadores sociais da diferença.***In this article, based on field research carried out between 2015 and 2018 in the city of São Paulo and digitally, I analyze the relationships between the private higher education market, advertising and social markers of difference (class, race and gender, in particular). If, historically, Brazilian advertising has favored white bodies and lifestyles associated with the middle class, in the recent period some transformations have been visible, incorporating more diverse student profiles, including several advertisements featuring young black women. My hypothesis in this article is that such transformations are related, on the one hand, to the phenomenon of greater access of the “class C” (according to the language of the market) in Brazilian private higher education since the mid-2000s. On the other hand, such advertisements started to incorporate some of the demands made by black and feminist movements. The incorporation of such transformations aimed at making advertising pieces more attractive to a new consumer of university degrees in Brazil. Keywords: private higher education, advertising, social markers of the difference.
É possível defender a ciência contra as ideologias?
Authors: Hümmelgen Bruno
Published: May 2021

Este trabalho busca identificar a possibilidade de existir uma ciência objetiva, livre de ideologias, no sentido comumente atribuído às ciências físicas. As ideologias podem ser utilizadas, primordialmente, de duas formas distintas: reforçar os interesses ou crenças individuais; ou confrontar as suposições ideológicas contrárias. Assim, mesmo que um campo da ciência possa ser construído sobre ideologias ou suposições teóricas enviesadas, os testes rigorosos pelos quais as teorias são submetidas aproximam as teorias da verdade e podem levar à rejeição daquelas contrárias as evidências disponíveis. A verdade mostra-se como um valor imprescindível, mas não o único, para a prática da ciência.
Apontamentos para uma educação como exercício de espanto
Authors: Ribeiro Luan Alves dos Santos
Published: May 2021

O presente ensaio tem por objetivo fazer apontamentos ontológicos acerca dos fundamentos da educação. Para tal, seguiremos a via do pensamento de Martin Heidegger, adentrando no âmbito da questão do ser (Seinsfrage). Para cumprir tal tarefa, subdividiremos o trabalho em três momentos distintos. Primeiramente, apresentaremos algumas críticas à educação como transmissão de conhecimento, como ensino humanista e como educação técnica. Após, apresentaremos alguns elementos basilares do pensamento heideggeriano. Por fim, faremos algumas reflexões e indicações de ordem hermenêutica e de ordem prática sobre a educação afim de pensarmos a sua essência (Wesen) como um perpétuo exercício de espanto.
Nós
Authors: Oliveira Simone Lucas Gonçalves de
Published: May 2021

O texto se refere a resenha de uma publicação cuja principal abordagem consiste na interação homem e máquina e nos aspectos que esta relação envolve - educacional, social, tecnológico, comunicacional, filosófico, etc, com a proposta de refletir a respeito das transformações que o homem sofreu a partir da invenção da internet e sobre como manter-se humano diante de tantas mudanças.
Alfabetização científica e Climatologia
Authors: Oliveira Jéssica Patricia , Zezzo Larissa Vieira , Coltri Priscila Pereira
Published: May 2021

Buscando integrar alunos em sala de aula e facilitar o trabalho do professor, este trabalho explorou possibilidades de relacionamento entre os princípios do Desenho Universal de Aprendizagem (DUA) e o ensino de Climatologia para elaboração de materiais didáticos. Produziu-se um modelo de livro em formato físico e de e-book sobre a temática das “Nuvens” e questões sobre ciclo hidrológico e estrutura da atmosfera. No e-book, os temas foram relacionados à questão das Mudanças Climáticas. A temática climatológica justifica-se por ser um assunto presente no cotidiano de todos; os conceitos, no entanto, não são compreendidos por toda a população. Conclui-se que, quando os princípios do DUA são utilizados desde a concepção do projeto, como no presente caso, é possível explorar, de maneira global, metodologias e ferramentas que ampliem as oportunidades de aprendizagem de pessoas que podem compor, ou não, o público-alvo da Educação Especial.
The international scientific-practical conference «Science, technology and information in libraries (LIBWAY-2020)»
Authors: Editorial Article
Published: May 2021

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On the 100th anniversary of Alexander Grigoryevich Zakharov, the first director of the Library for Natural Sciences of RAS
Authors: Glushanovsky A. V. , Kalenov N. E. , Levner M. V.
Published: May 2021

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Theoretical resources of bibliography
Authors: Sokolov A. V.
Published: May 2021

The author estimates the scientific and practical value of the theory of information resource studies presented in domestic and foreign publications by T. F. Berestova, Professor of Chelyabinsk State Institute of Culture.
Laparoscopic vs Open Pancreaticoduodenectomy- An Updated Metaanalysis of Randomized Control Trials
Authors: Vasavada Bhavin , Patel Hardik
Published: May 2021

Background: There is ongoing debate regarding the usefulness of laparoscopic pancreaticoduodenectomy. This study aimed to analyze all the randomized control trials published including the most recent one. Material and methods: The study was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement and MOOSE guidelines. Heterogeneity was measured using Q tests and I2. The random-effects models were used to summarise the relative risks, odds ratios, and mean differences as appropriate.Results:4 RCTs were included consisting of 818 patients. 411 patients were in the laparoscopic group and 407 in the open pancreaticoduodenectomy group. Weighted baseline patient characteristics were similar except more patients with pancreatic adenocarcinoma and more males were there in the open pancreaticoduodenectomy group. There was no difference in-hospital stay,90 days complications rate, 90 days mortality, R1 resection, postoperative pancreatic fistula, delayed gastric emptying, post pancreatectomy hemorrhage, bile leak between the two groups. Operative time was more in the laparoscopic group. Blood loss [mean difference -132.12 ml (-172.60,-91.65)] and surgical site infection [Risk ratio 0.41 ( 0.17-1.0)] were significantly lesser in laparoscopic group.Conclusion:There was no benefit in-hospital stay or clinical outcomes after laparoscopic pancreaticoduodenectomy. Blood loss and surgical site infection were lesser in laparoscopic pancreaticoduodenectomy.
Photonics Crystal Fiber Sensor Using for Sensing Environmental Pollution
Authors: S.Hassan* Omar
Published: May 2021

The aim of this paper is to create a sensor model based on optical crystal fibers (PCF). The aim of this model is to find and identify zinc cadmium. This thesis looked at three different categories of concentrations. For sensor architecture, PCF was generated using single-mode fiber-to-end split fusion (SM-PCF-SM). In this experiment, a specific wavelength spectrum was used to alter the concentration of materials covering the fiber in order to demonstrate the fiber's sensing capability. The 550nm wavelength has been used as the optical source for the fiber. The change in the output power of the external light was monitored and changes were observed for each concentration of the concentrations around the fiber. It has been found that the fiber is sensitive to small changes in concentrations. The absorption of the fiber has been calculated for the incoming capacity, as well as the losses in the capacity outside the fiber.
METHOD OF THE IT PROJECT TEAM CREATION BASED ON MAXIMIZING IT’S COMPETENCIES
Authors: Kononenko Igor , Sushko Hlib
Published: May 2021

The use of agile approaches in software development requires the project team to be multifunctional and self‑organized in order to respond effectively to changing project requirements. Therefore information technology project team creation requires a special method. The purpose of the work is to develop a method of IT-project team creation by maximizing it’s competencies taking into account the features of agile approaches to project management. The paper proposes the issue of team creation based on maximizing team competencies under conditions of budget and laboriousness constraints. A method of a project team creation is proposed, which takes into account the requirements of the project, the characteristics of individual candidates, and the general competencies of the team as a whole, as well as the project's limitations on the budget and laboriousness of the project. The proposed approach consists of three stages. At the first stage, a set of candidates is determined, whose competency assessments meet the requirements of the project. In the second stage, team options are formed in accordance with the requirements of the project. The project team creation can take place in several statements. The first statement is to solve the problem of minimizing the distance between the vector of team competencies and the vector of requirements. The second statement of the problem is to solve the problem of maximizing competencies in terms of time and project budget constraints.The third solves the issue of choosing a team according to the chosen setting. Two possible objective functions of the issue are offered. One target function is to create a team that will include candidates with maximum competencies. Such a team will best cope with the requirements that are known at the start of the project. The second target function maximizes the total competencies of the team that exceed a given threshold. As a result, the team will be able to better cope with the changing requirements of the project. The proposed method makes it possible to create an effective software development team that meets the requirements of the project, the values and principles of agile approaches.
REVIEW AND CLASSIFICATION OF ART-PROJECTS’ FEATURES AS RISK FACTORS
Authors: Danchenko Elena , Rybalko Iryna , Zarutskyi Serhii , Bielova Olena
Published: May 2021

An overview of the features of art projects as possible threats to the planning and implementation of projects in the creative sphere in the following areas is offered: psychological aspects of personality and the specificity of art projects, which are characteristic exclusively for projects in this sphere. It has been determined that the combination of factors of the internal and external environment is the basis for the formation of the list and ranking of risks of art projects. A detailed analysis of scientific works devoted to research in the implementation of the design approach in the creative field, the study of psychological traits that significantly distinguish a creative person from the psychology of other people and research in the field of risk management, has proved that the attention of the scientific community on the study of risks and their nature origin in art projects today is very insignificant.  The introduction of the methodology of the project approach to the organization and implementation of creative events in Ukraine is still rather weak, and anti-risk measures begin to be developed only after the onset of risk. Therefore, the issue of studying the risks in the implementation of art projects remains relevant and in demand. Analysis of the psychological traits of creative personalities and the specificity of art projects as sources of origin of risks made it possible to develop types of risks for their subsequent classification. It is concluded that the presented classification scheme is of practical value for art project managers. It will allow in the future to envisage options for the development of events, to determine in advance the factors of influence of the external and internal environment of the art project and to develop in advance measures, methods and techniques to prevent a risk event or, in case of its occurrence, to minimize negative consequences for achieving the goals of the art project (time, budget, content, quality). Now the list of types of risks of art projects includes only two sources of risks’ origin. But work on drawing up a risk classification scheme for art projects will continue to include the maximum possible sources of risk origin and provide the project manager with an effective tool for identifying and analyzing possible threats (risks) or opportunities.
IDENTIFICATION AND RISK ANALYSIS OF IT-AUDIT PROJECTS
Authors: Danchenko Elena , Alba Victor , Berezensky Ruslan , Savina Oksana
Published: May 2021

In a relatively short period of time, the field of information technology from a conventional, sometimes secondary industry, has become one of the main drivers of the world economy, becoming a catalyst for tectonic changes and transformations in many other industries. The Ukrainian IT industry now successfully competes in the global market and is a reliable source of foreign exchange earnings. Today, Ukrainians can create, promote and sell IT products in global markets. They are interested not only in creating a product, but also in its active development. The productive and efficient operation of IT enterprises requires constant monitoring and control of the real state of the IT infrastructure. Assessment of the state of information and / or financial system of the enterprise is urgent and necessary. Therefore, IT audits are being introduced more and more often at such enterprises. It needs skillful and effective management to achieve the best results. Based on the results of the analysis of the works of domestic and foreign scientists and researchers in the field of IT audit project management, it is concluded that this aspect is poorly studied. IT audit projects have specific risks. These risks need to be investigated in detail. Using the method of the causal diagram of Ishikawa, the article identifies the factors influencing the increase in time and cost of IT audit projects. It was found that a significant part of the deviations and uncertainties that lead to an increase in time and cost are directly related to the stockholders of IT audit projects. Stakeholders of IT audit projects have been identified. Stakeholders include: owner, initiator, customer, investor, project managers, project team or auditors, competitors and other stakeholders. The influence of the main groups of stakeholders on reducing the time and cost of IT audit projects using the method of the causal diagram of Ishikawa is analyzed. Through the prism of opportunities and threats of stakeholders of IT audit projects, the risks of these stakeholders for projects are identified.
THE ORETICAL AND METHODOLOGICAL FUNDAMENTALS OF RESEARCH OF ANTI-RISK STAKEHOLDERS OF PROJECT MANAGEMENT
Authors: Król Konrad
Published: May 2021

Projects of the agro-industrial complex are implemented in conditions of high uncertainty and risk. Agricultural products provide variety and quality of food to the population. To reduce production losses and the quality of crop and livestock products, and as a consequence of reducing the economic efficiency of production, it is necessary to take measures to prevent and reduce the risks of agro-industrial projects. Given that the risks associated with stakeholders can have devastating consequences for the project, anti-risk stakeholders of projects management is critical. In connection with the widespread use of international teams for project implementation, the author proposes to take into account when managing stakeholders of projects their mentality, which can be a cause of misunderstandings and conflicts. The author also emphasizes the importance of identifying and managing the expectations of project stakeholders. The article presents the principles of stakeholders of projects management and analyzes the stakeholders of projects management processes in international project management standards, in particular P2M, ICB IPMA, PMBoK PMI and ISO 21500. The author also provides principles of project risk management in accordance with international project management standards, in particular P2M, ICB IPMA, PMBoK PMI and ISO 21500. It was found that the identification and analysis of stakeholders is the basis for understanding what risks associated with each stakeholder may arise during the project. The author emphasizes that it is impossible to analyze the risks associated with them without conducting a detailed analysis of stakeholders. And developing a stakeholder risk response plan depends largely on the characteristics of each particular stakeholder and understanding which leverage can be effective in a given stakeholder. For more effective anti-risk stakeholders of agro-industrial projects management, which would take into account the specific risks of such projects, the author recommends to develop and use tools that would take into account the characteristics of stakeholders involved in agro-industrial projects.
IMPROVEMENT OF KEY COMPETENCIES OF PROGRAMS FOR BIADAPTIVE DEVELOPMENT OF DESIGN-ORIENTED ORGANIZATIONS
Authors: Chеrnovа Liubava , Chеrnovа Lyudmila , Voitenko Oleksandr , Timinsky Alexander
Published: May 2021

The programs of bi-adaptive development of project-oriented organizations as a basis for ensuring their competitiveness are considered. The task is to improve the individual competencies of employees, organizational competence and key competence of the project-oriented organization based on cognitive models. The methodological approach to the implementation of programs of bi-adaptive development of project-oriented organizations on the basis of cognitive improvement of their key competencies is formulated. The concept of key competence has been further developed. The concepts and ways of development of key competence of project-oriented organizations as bases of the cognitive mechanism of maintenance of success of programs of their bi-adaptive development are formulated. In the development of existing research, a model of the key competence of the program of bi-adaptive development of a project-oriented organization is proposed. It is concluded that to solve complex problems of bi-adaptive development programs, the use of standard methods of linear optimization is not enough, because the classical problem of linear optimization does not take into account additional conditions arising in the transition from one state to another in bi-adaptive development programs. competencies. For such problems it is proposed to use the dual problem of linear optimization. The proposed formalization will help solve the problem of synchronized development of staff competencies in order to obtain cognitive synergy and improve the cognitive potential of the project-oriented organization in bi-adaptive development programs. The approach of holacracy as a means of bi-adaptive cognitive improvement of competencies of the management team of the program of by-adaptive development of project-oriented organizations is offered. Prospects for further research in the chosen direction are outlined.
CONCEPTUAL PROCEDURE FOR ESTIMATING THE PERFORMANCE PROJECT BASED ON FLEXIBLE SCRUM METHODOLOGIES IN THE FIELD OF INFORMATION TECHNOLOGIES
Authors: Prokopenko Tetiana , Povolotskyi Yaroslav
Published: May 2021

The research and substantiation of the conceptual procedure of evaluation of efficiency of IT projects which are realized on the basis of application of flexible methodology of Scrum is offered. This procedure will increase the efficiency of the IT project, as well as reduce its implementation time. The substantiation and choice of the criterion for evaluating the effectiveness of the IT project, which takes into account the human factor, is presented. Evaluation is based on human resources research, namely the characteristics of project team members. Conceptually, the procedure for evaluating the effectiveness of an IT project is a complex multi-stage iterative process that requires consideration of the team implementation of IT project processes. The transparency of Scrum's general terms and standards of flexible methodology provides the possibility of the expected result. Therefore, continuous evaluation of performance at each stage of Scrum will increase productivity and help to identify deviations at an early stage, when they can be quickly eliminated or corrected. Based on this, we can identify the following main stages of evaluating the effectiveness of IT projects implemented in the flexible methodology of Scrum. An integrated indicator of project team competence was obtained, which provides opportunities to reconcile the company's IT goals and opportunities to reduce requirements, as well as the decision to continue research by expanding existing options or synthesis of new options with appropriate variation of indicators, weights, composition of elements. Conclusions are made about the possibility of applying the research in the development of an intelligent system for evaluating the effectiveness of the IT project based on determining the level of competence of project team members, which will reduce project implementation time and increase IT project efficiency.
A Novel Minimally Invasive Spherical Periacetabular Osteotomy
Authors: Kaneuji Ayumi , Hara Toshihiko , Takahashi Eiji , Fukui Kiyokazu , Ichiseki Toru , Kawahara Norio
Published: May 2021

Background:

Spherical periacetabular osteotomy (SPO) is a novel osteotomy involving splitting the teardrop, using patient-specific preoperative planning, and requiring only a 7-cm skin incision. We report preoperative planning methods and short-term results of SPO.

Methods:

In preoperative planning, computed tomography (CT) images were imported into 3-dimensional templating software. The radius of the curved chisel was mapped to pass through the teardrop, the infracotyloid groove of the ischium, and the area between the anterior superior iliac spine and the anterior inferior iliac spine. The osteotomy height and the predicted depth of osteotome insertion were measured, and those values were reproduced during surgery. We performed a retrospective analysis of data on 52 consecutive patients (55 hips) with hip dysplasia who underwent SPO and were followed for at least 2 years: 27 hips had Tönnis grade 0, 21 had grade 1, and 7 had grade 2. The mean age at surgery was 38 years (range, 17 to 56 years). The rotated bone fragment and iliac crest were fixed with absorbable screws. Statistical analysis was performed with the paired t test.

Results:

The mean (range) of the lateral center-edge and sourcil angles were 6.0° (−20° to 18°) and 26.0 (13° to 38°), respectively, before surgery and 30.0° (15° to 43°) and 3.8° (−4° to 27°), respectively, after surgery (p < 0.001). However, 11 hips (20%) showed a loss of correction of bone rotation (<3 mm) or the sourcil angle (<3°). Radiographs showed bone union in all hips within 3 months after the surgery. Early second surgery related to absorbable screws was performed in 2 hips. No patient had required conversion to total hip arthroplasty at the time of writing. Clinical scores were significantly improved at the 2-year follow-up (p < 0.001). Paresthesia of the lateral femoral cutaneous nerve area was very common but had resolved in 92% of the patients at the 2-year follow-up.

Conclusions:

SPO is a novel minimally invasive periacetabular osteotomy that has the potential disadvantage of early loss of correction (observed in 20% of the hips in the present study) but may provide the benefit of decreasing the risk of nonunion at the pubis osteotomy site.

Level of Evidence:

Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Persistence and baseline determinants of seropositivity and reinfection rates in health care workers up to 12.5 months after COVID-19
Authors: Dobaño Carlota , Ramirez Anna , Alonso Selena , Vidal-Alaball Josep , Ruiz-Olalla Gemma , Vidal Marta , Rubio Rocio , Cascant Emma , Parras Daniel , Melero Natalia Rodrigo , Serra Pau , Carolis Carlo , Santamaria Pere , Forcada Anna , Mendioroz Jacobo , Aguilar Ruth , Moncunill Gemma , Ruiz-Comellas Anna
Published: May 2021

We assessed the duration and baseline determinants of antibody responses to SARS-CoV-2 spike antigens and the occurrence of reinfections in a prospective cohort of 173 Spanish primary health care worker patients followed up initially for nine months and subsequently up to 12.5 months after COVID-19 symptoms onset. Seropositivity to SARS-CoV-2 spike and receptor binding domain antigens up to 149-270 days was 92.49% (90.17% IgG, 76.3% IgA, 60.69% IgM). In a subset of 64 health care workers who had not yet been vaccinated by April 2021, seropositivity was 96.88% (95.31% IgG, 82.81% IgA) up to 322-379 days post symptoms onset. There were four suspected reinfections detected by passive case detection, two among seronegative individuals (five and seven months after the first episode), and one low antibody responder. Antibody levels significantly correlated with fever, hospitalization, anosmia/hypogeusia, allergies, smoking and occupation. Stable sustainment of IgG responses raises hope for long-lasting COVID-19 vaccine immunity.
Studies on Clarification of Coal Washery Effluent Using Polymeric Flocculants and Settling Kinetics
Authors: Pimpalkar Sarika Narayanrao , Suresh Nikkam , Singh Gurdeep
Published: May 2021

Settling tests were conducted on the washery effluent using three types of flocculants namely cationic (Telfloc-3674F), anionic (Magna-1011) and non-ionic (Nalco-83370+). For the study purpose coal washery effluent (having pH of 8.72) was collected from a newly commissioned plant-thickener. Tests were conducted by varying the pH of the pulp at three levels of acidic (4.0), alkaline (11.0) and the natural pH (8.72) of the as collected effluent, besides the flocculent dosages varied at four levels (2, 4, 6 and 8 gpt) for each of the flocculants stated. The results of these tests, estimated in terms of initial settling rate and turbidity indicated that; among the three flocculants tested Telfloc-3674F and Magna-1011 gave best results as compared to Nalco-83370+ flocculent at a washery water pH 8.72. The effect of molecular weight of the flocculants on settling of solids in effluent has been established in terms of the kinetics with a characteristic number for each of the type of flocculants used.
Natural History of Urinary Incontinence from First Childbirth to 30 Months Postpartum
Authors: Patel Krishna , Long Jaime B. , Boyd Sarah S. , Kjerulff Kristen H.
Published: May 2021

Purpose The objectives of this study were to determine the incidence of UI in a large cohort of primiparous women before and during pregnancy and over the course of 30 months postpartum, and to identify risk factors for UI during and after pregnancy. Methods Nulliparous women aged 18 to 35 years with singleton pregnancies were interviewed in their third trimester and asked about urinary incontinence before and during pregnancy (n = 3001). After delivery these women were interviewed at 1, 6, 12, 18, 24 and 30 months postpartum and asked about urinary incontinence occurring in the month prior to each interview. Multivariable logistic regression models identified risk factors for UI during pregnancy and during the follow-up period.Results Overall, 4% reported having urinary incontinence before pregnancy and 36.8% during pregnancy. The strongest predictor of urinary incontinence during pregnancy was urinary incontinence before pregnancy (adjusted OR 13.11, 95% CI 7.43-23.13). Among the women with no subsequent pregnancies, the rate of urinary incontinence increased from 12.5% at 6 months postpartum to 27.4% at 30 months postpartum, 52.1% reported UI at one or more postpartum data collection stages, and the strongest predictors of postpartum UI were UI before pregnancy (adjusted OR 3.95 (95% CI 1.60-9.75) and during pregnancy (adjusted OR 4.36, 95% CI 3.24-5.87). Conclusion Our findings suggest that primiparous women who report UI before and during pregnancy should be monitored for the continuation or worsening of UI over the course of the first 2-3 years postpartum, and treatment options discussed.
Bioprocess optimization of PHB production utilizing agro (sago) waste as a sustainable substrate by the native isolate, Bacillus cereus
Authors: Murugan Sriramani , Duraisamy Senbgam , Balakrishnan Senthilkumar , Kumarasamy Anbarasu , Raju Amutha
Published: May 2021

Microbial synthesis of polyhydroxyalkanotes (PHA), the eco-friendly biopolymers are gaining more attention towards restricting the environmental pollution by substituting conventional non-biodegradable petroleum-based plastics. The current study was aimed to economize the polyhydroxybutyrate (PHB) production by optimizing the production media using sago waste, as a substrate and cheapest carbon source, by Bacillus cereus a native isolate obtained from soil where sago waste is disposed in and around Salem District, Tamil Nadu, India. PHB production media was optimized by Placket Burman design and Box Benhen design (pH (X1 = 7.07) temperature (X2 = 36.36°C) sago waste (X3 = 19.7g/l)) and observed a maximum OD values of 2.006 in shake flask culture. The dry weight of PHB extracted under optimized condition was also measured by chloroform extraction method and it was found to be 5.2g/l. In addition, Fourier- transform infrared spectroscopy (FTIR), thin layer chromatography (TLC) and Gas Chromatography- Mass Spectrometry (GC-MS) analysis revealed the characteristic features of PHB polymer. Thus this study concludes that the utilization of sage waste for synthesis of value-added products, PHB will not only help in reducing the cost of PHB production process, but also assist to manage the problem associated with solid waste disposal.
End-to-end Relation-Enhanced Learnable Graph Self-attention Network for Knowledge Graphs Embedding
Authors: Jiang Shengchen , Wang Hongbin , Hou Xiang
Published: May 2021

The existing methods ignore the adverse effect of knowledge graph incompleteness on knowledge graph embedding. In addition, the complexity and large-scale of knowledge information hinder knowledge graph embedding performance of the classic graph convolutional network. In this paper, we analyzed the structural characteristics of knowledge graph and the imbalance of knowledge information. Complex knowledge information requires that the model should have better learnability, rather than linearly weighted qualitative constraints, so the method of end-to-end relation-enhanced learnable graph self-attention network for knowledge graphs embedding is proposed. Firstly, we construct the relation-enhanced adjacency matrix to consider the incompleteness of the knowledge graph. Secondly, the graph self-attention network is employed to obtain the global encoding and relevance ranking of entity node information. Thirdly, we propose the concept of convolutional knowledge subgraph, it is constructed according to the entity relevance ranking. Finally, we improve the training effect of the convKB model by changing the construction of negative samples to obtain a better reliability score in the decoder. The experimental results based on the data sets FB15k-237 and WN18RR show that the proposed method facilitates more comprehensive representation of knowledge information than the existing methods, in terms of Hits@10 and MRR.
Rare earth elements’ waste management for smartphones’ touch screens by system dynamics modelling
Authors: Konyalıoğlu Aziz Kemal , Bereketli Ilke
Published: May 2021

Developments in smartphones’ technology affect mobile phone use rates in the world. Increasing use of internet in the last 10 years parallelly force people to use smartphones not only in the work but also in their private lives. This high amount of consumption brings together the problem of excessive amount of waste, and also raises environmental concerns about how to treat them in the end-of-life phase of the smartphones. It is known that a classic smartphone, which is composed of battery, electronics, case part and touch screen, can be dissembled and recycled even though less than 20% of smartphones are going through reusing and recycling in the world. One of the problematic parts of the smartphones’ waste management is the touch screen. Rare earth elements used in touch screens are scarce sources, which are mainly silver, gold, palladium, indium, gadolinium, terbium, yttrium and lanthanum, and these elements cannot be easily substituted. In case they are not reused or recycled, they will be lost forever. In this paper, it is aimed to propose a system dynamics model for rare earth elements’ reuse and recycling in smartphones’ touch screens by a closed loop supply chain view. The design of the system dynamics modelling is operated and simulated by Anylogic and Stella simulation softwares which give perspective to observe how to better manage rare earth elements’ closed loop supply chain in order to increase the rate of reuse and recycling by considering important and relative factors of waste management system.
Angiocholitis due to Hydatid Cyst of the liver fistulized in the bile ducts: Comparative study between surgical treatment and endoscopic treatment
Authors: Marghich Omar , Hamdane Amine , Anis Tarek , Alila Mohamed , ousadden Abdelmalek , Taleb Khalid Ait , Ibrahimi Sidi Adil , benajah dafr-allah , Mazaz Khalid , Benjelloun EL Bachir
Published: May 2021

Background: Liver hydatid is a parasitic disease considered benign but can become dangerous because of its complications. The fistula in biliary tract remains one of the most feared complications by its frequency, morbidity and mortality.Materials and methods:We present a descriptive and comparative retrospective study at the university hospital Hassan II of Fez. This study was carried out on 63 cases of angiocholitis on hydatid cyst of the liver fistulized in the bile ducts and extends over a period of 5 years from January 2015 to December 2019. The objective of this study is to evaluate and compare the contribution of different therapeutic modalities in the treatment of cystic biliary fistula (Surgical treatment against endoscopic treatment).Results: Surgical treatment was used in 22 patients against 41 patients who underwent endoscopic treatment. The success rate of endoscopic treatment was higher than that of surgical treatment (83% against 73 %, p = 0.350). The mortality rate was reduced in the endoscopy group compared with patients in the surgery group (5% against 14 %, p = 0.226). General morbidity and major morbidity were higher significantly in patients treated surgically (General morbidity: surgery 41% against 2% for endoscopy, P0.05Conclusion:Endoscopic treatment should be considered as the treatment of choice for angiocholitis due to hydatid cyst of the liver fistulized in the bile ducts.
Epigenetic Regulation of Mammalian Target of Rapamycin Debilitates Insulin Resistance Associated Alzheimer Disease Condition in Rats
Authors: Kakoty Violina , KC Sarathlal , Dubey Sunil , Yang Chih Hao , Taliyan Rajeev
Published: May 2021

Insulin resistance (IR) and accumulation of amyloid beta (Aβ) oligomers are potential causative factor for Alzheimer Disease (AD). Simultaneously, enhanced clearance level of these oligomers through autophagy activation bring novel insights into their therapeutic paradigm. Autophagy activation is negatively correlated with mammalian target of rapamycin (mTOR) and dysregulated mTOR level due to epigenetic alterations can further culminate towards AD pathogenesis. Therefore, in the current study we explored the neuroprotective efficacy of rapamycin and vorinostat in-vitro and in-vivo. Aβ1−42 treated SH-SY5Y cells were exposed to rapamycin (20µM) and vorinostat (4µM) to analyse mRNA expression of amyloid precursor protein (APP), brain derived neurotrophic factor (BDNF), glial cell derived neurotrophic factor (GDNF), neuronal growth factor (NGF), beclin-1, microtubule-associated protein 1A/1B-light chain 3-phosphatidylethanolamine conjugate, lysosome-associated membrane protein 2 and microtubule associated protein 2. In order to develop IR condition, rats were fed a high fat diet (HFD) for 8weeks and then subjected to intracerebroventricular Aβ1−42 administration. Subsequently, their treatment was initiated with rapa (1mg/kg, i.p.) and vori (50mg/kg, i.p.) once daily for 28days. Morris water maze was performed to govern cognitive impairment followed by sacrification for subsequent biochemical and histological estimations. For all the measured parameters, a significant improvement was observed amongst the combination treatment group in contrast to that of the HFD + Aβ1−42 group and that of the groups treated with the drugs alone. Outcomes of the present study thus suggest that combination therapy with rapa and vori provide a prospective therapeutic approach to ameliorate AD symptoms exacerbated by IR.