bluuebunny/crossref_metadata_2025 huggingface dataset:
Dendam Trigantalpati
Authors: Sudarsono Hening , Udreka Udreka , Intarti Retno Dwi
Published: January 2025

AbstractThe puppet performance Dendam Trigantalpati is a reinterpretation of the story of Tri- gantalpati which is sourced to three performance, namely Banjaran Sengkuni Ki Purbo Asmoro, Jumenengan Pandhu Ki Manteb Sudarsono, and Gandamana Tundhung version of Ki Hadi Sugito. The concept of sanggit Soetarno, et al. was used to respond to the three performance. The method used in this work is the exploratory method. The stages that go through are observing the play, selecting and sorting out events, processing events, compiling plays. The result of the reinterpretation of the three performance above is Trigantalpati as someone who cannot control ego and revenge.AbstrakLakon Dendam Trigantalpati adalah sebuah tafsir ulang kisah Trigantalpati yang bersumber pada tiga lakon yaitu lakon Banjaran Sengkuni versi Ki Purbo Asmoro, Jumenengan Pandhu versi Ki Manteb Sudarsono, dan Gandamana Tundhung versi Ki Hadi Sugito. Konsep sanggit Soetarno, dkk. digunakan untuk merespon tiga lakon tersebut. Metode yang digunakan dalam karya ini adalah metode eksploratif. Adapun tahapan yang dilalui adalah mencermati lakon, memilih dan memilah peristiwa, mengolah peristiwa, menyusun lakon. Hasil tafsir ulang dari tiga lakon di atas adalah Trigantalpati sebagai seseorang yang tidak bisa mengendalikan ego dan rasa dendam.
Alih Wahana: dari Cerita Alkitab ke Naskah Pakeliran Wayang Warta Lakon Absalom
Authors: Kristiaji Kristiaji , Krystiadi Krystiadi
Published: January 2025

AbstractThis paper aims to see the change of medium from Bible stories to Wayang Warta performance scripts for Lakon Absalom. The research data was in the form of script of Lakon Absalom. The transformation concept of Sapardi Djoko Damono was used in this study. The concept says that transformation is the changing and transfer of “something” from one type of medium to another. Every transformation activity always changes and adjustments. Qualitative descriptive methods were used in this study. The first step is to read and summarize the Bible story related to Lakon Absalom. Next, read the script of the wayang warta Lakon Absalom and summarize it according to the structure of the puppet performance. Finally, it examines the process of transformation from the Bible to the script of wayang warta performances. The result obtained is that the ideology contained in the script of the wayang warta performances still refers to the ideology contained in the Bible. In the case of such transformations, there are changes including plot elements, chess, and characters.AbstrakTulisan ini bertujuan melihat perubahan wahana dari cerita Alkitab menjadi naskah pertunjukan Wayang Warta lakon Absalom. Data penelitian berupa Naskah Lakon Absalom. Konsep alih wahana Sapardi Djoko Damono digunakan dalam penelitian ini. Konsep tersebut mengatakan bahwa alih wahana adalah pengubahan dan pemindahan “sesuatu” dari satu jenis wahana ke jenis wahana lain. Setiap kegiatan alih wahana selalu terjadi perubahan dan penyesuaian. Metode deskriptif kualitatif digunakan dalam penelitian ini. Langkah pertama yang dilakukan ialah membaca dan meringkas cerita Alkitab yang berkaitan dengan lakon Absalom. Selanjutnya  membaca naskah wayang warta lakon Absalom dan meringkasnya menurut pola bangunan wayang. Terakhir, mengkaji proses alih wahana dari Alkitab ke naskah pertunjukan wayang warta. Hasil yang diperoleh yaitu ideologi yang terdapat dalam naskah pertunjukan wayang warta masih mengacu pada ideologi yang dikandung dalam Alkitab. Dalam kasus alih wahana tersebut terdapat perubahan meliputi unsur alur, catur, dan tokoh.
Factors for Manipulating the Tolerance of the Search Method Used in Genetic Algorithms to Determine Nanoclusters
Authors: Galvão Breno Rodrigues Lamaghere , Carvalho Junior Nelson Ribeiro de
Published: January 2025

Objective: The objective is to present a new method to explore BFGS where a new decision-making flow was added in order to optimize and computationally improve the performance of the Genetic Algorithm, controlling the value of the gradient as it evolves.
 
Theoretical Framework: In the literature, the work presented by [Chen, 2014] stands out, who proposed that there must be a repulsive contribution to ensure the stability of the structure, which is introduced as the interaction between atomic pairs that makes up the second term of the cohesion energy. [Goldberg,1989] proposed the use of a genetic algorithm to search for available minima in the potential energy function associated with clusters.
 
Method: The methodology adopted in this research was the use of Evolutionary Algorithms (EAs) are inspired by the principle of natural selection and survival of the fittest individuals, discovered by physiologist Charles Darwin and described in his book "The Origin of Species", from 1859. Among various selection methods, the roulette wheel method was used, as it is useful in problems where diversity needs to be maintained to avoid premature convergence. The crossover used by Deaven and Ho, which is a technique known as the cut-and-splice method, applied in the context of optimizing molecular structures or atomic clusters and the aluminum and magnesium clusters that were explored using a Genetic algorithm applied to Gupta potential function and tuned to look for the lowest energy minima for each cluster size.
 
Results and Discussion: The results obtained revealed [synthesize the main results of the research]. In the discussion section, these results are contextualized in light of the theoretical framework, highlighting the implications and relationships identified. Possible discrepancies and limitations of the study are also considered in this section.
 
Research Implications: The objective of this article was to present a new method to explore BFGS where a new decision-making flow was added in order to optimize and computationally improve the performance of the Genetic Algorithm, controlling the value of the gradient as it evolves. This new method proved to be very promising according to the results presented in the previous section, since the Sequential Genetic Algorithm, which becomes quite costly as it invokes the BFGS optimization method, always has a very small Gradient vector error, unlike the Genetic Algorithm which It starts with a very low value and is gradually increased according to established criteria. In experiments carried out with both 10 seeds and 30 seeds, the Genetic Algorithm obtained better energies in the general average and the standard deviation was also much better, reaching better global minimums.
 
Originality/Value: This study contributes to the literature by creating new flows in the Genetic Algorithm, enabling computational gains in the processing of experiments, which was proven in the results obtained.
Energy efficient green building design utlilising renewable energy and low-carbon development technologies
Authors: Sagar  , Arya Yogendra , Singhal Poonam
Published: January 2025

The core issue these days is to reduce carbon dioxide (CO2) emission and prevent the hole in the ozone layer. Numerous emerging environmental crises successfully tackled by coordinated global efforts in the past few years. Despite this, the present climate emergency is a much more serious threat than anything we have ever encountered and requires much more action consequently. Today, more attention is paid on green buildings in the society, which will make use of the sustainable and energy-efficient buildings a necessity for future generations. Hence, this paper proposes a novel design model of an energy-efficient residential green building with low carbon emission to maintain the health and enhances the productivity and living standards of inhabitants. Green building technology is utilised to enhance energy efficiency and lower carbon emission. This design considers green, recyclable, and eco-friendly building materials, which are beneficial for human health and comply with relevant Indian standards and building codes. This building design proposes Renewable Energy Sources (RES) integrated with the power grid, although RES powers most of the load of the proposed green building. The suggested green building design shows effective results, i.e., building energy consumption has reduced by 50.54%, total energy consumption cost has reduced by 57.41%, and CO2 emission per month has reduced by 50.54%. In addition, stormwater-harvesting system is proposed to collect 54,322.23 L of rainwater annually, which helps in water conservation and contributes to improve the groundwater level. The proposed solid waste management plan has contributed to the achievement of regional and national Sustainable Development Goals (SDGs). Finally, there are some suggestions to promote the use of green buildings for sustainable development.
The Role of Image-Guided Superficial Radiation Therapy in the Treatment of Nonmelanoma Skin Cancer
Authors: Zakria Danny , Burshtein Joshua , Shah Milaan , Cockerell Clay , Goldenberg Gary , Nestor Mark , Sarnoff Deborah , Weinkle Susan , Rigel Darrell , Del Rosso James Q.
Published: January 2025

Background: Basal cell carcinoma (BCC) and squamous cell carcinoma, collectively referred to as nonmelanoma skin cancer (NMSC) are the most common type of skin cancer and can lead to significant morbidity and mortality. There are several treatment options available for NMSC including superficial radiation therapy (SRT), which has improved in recent years with the addition of image guidance (IGSRT). In some cases, patients are not offered IGSRT as a treatment option and additional guidance on its benefits may be beneficial.
Objective: For a panel of expert dermatologists to review published studies on IGSRT for the treatment NMSC and create consensus recommendations on its use.
Methods: A comprehensive literature search of PubMed, EMBASE, Scopus, and Google Scholar was completed for English-language original research articles on the use of IGSRT to treat NMSC. A panel of six dermatologists with significant expertise in treating NMSC convened to review the articles and create consensus statements based on the available data. A modified Delphi process was used to approve each statement for adoption and a strength of recommendation was assigned using Strength of Recommendation Taxonomy (SORT) criteria.
Results: After screening the articles that met the initial search criteria, 12 articles were distributed to the panelists for review prior to the roundtable discussion. The panel unanimously voted to adopt eight statements with an additional two statements receiving five out six votes for adoption. Eight of the statements received a strength of recommendation of “A” while two of the statements were given a strength of recommendation of “B” based on SORT criteria.
Conclusion: IGSRT is a safe and effective treatment for NMSC that often results in highly favorable cosmetic outcomes. It can be considered a first-line treatment option for appropriately selected cases of NMSC.
Improvement of Suspected Linear Morphea seen with Topical Ruxolitinib
Authors: Amara Shivkar , Lopez Miyahra , Lebwohl Mark
Published: January 2025

Linear morphea is an autoimmune skin condition characterized by localized sclerosis and discoloration. Current standard of care includes topical and intralesional steroids, phototherapy, and immunosuppressive agents; however, no gold-standard treatment exists. We present a 34-year-old female who presented with a hypopigmented and indurated plaque in an en coup de sabre configuration on her forehead, suspicious of linear morphea, that improved significantly in thickness and hypopigmentation after eight weeks of 1.5% ruxolitinib cream.
Representation and Quality of Acne-Related Content on Social Media
Authors: Zoltan Samantha , Silverberg Nanette
Published: January 2025

Acne is a common dermatological condition affecting individuals of all races and ethnicities, with most cases occurring in teenagers and young adults. Patients in these age groups frequently turn to online platforms for guidance, relying on videos on social media platforms like TikTok. This study evaluated the top TikTok videos' content quality (DISCERN score) about perceived racial/ ethnic diversity. Findings demonstrate that videos showcasing the skin of individuals of color tend to have lower scientific content and potentially feature the application of agents that would promote dyspigmentation and scarring. There is a need to improve acne-related social media posts to provide higher-quality content targeted at patients of color, focusing on safer therapeutics.
Alopecia Areata and Vitamin D3 Deficiency: The Potential of Calcipotriol as a Treatment
Authors: Majewski Michał
Published: January 2025

Background: Alopecia areata is a non-scarring form of hair loss associated with the loss of the hair follicle immune privilege with a prevalence of 2% in the population. It results in an accumulation of lymphocytes around the lower part of the hair bulb ultimately leading to hair loss.
Discussion: Vitamin D3 deficiency is significantly more prevalent in patients with alopecia areata than in healthy populations and correlates with disease severity. Screening patients with alopecia areata for vitamin D3 deficiency could be beneficial, potentially allowing for supplementation. The pathogenic involvement of vitamin D3 in alopecia areata is attributed to its regulatory impact on immune and epidermal cells’ function, particularly through modulation of the JAK/STAT pathway, T lymphocytes proliferation and hair follicle damage.
Conclusion: The data on the effectiveness of vitamin D3 supplementation and topical calcipotriol in treating alopecia areata are inconsistent, and the evidence supporting their efficacy is primarily of low quality. This article underscores the need for randomized, placebo-controlled studies with large patient cohorts to evaluate the efficacy of calcipotriol in the treatment of alopecia areata.
Long-Term Efficacy and Safety of Lebrikizumab Is Maintained in Patients With Moderate-to-Severe ​ Atopic Dermatitis: Results Up to 3 Years From ADjoin
Authors: Guttman-Yassky Emma , Irvine Alan , Simpson Eric , Gooderham Melinda , Weidinger Stephan , Spelman Lynda , Silverberg Jonathan , Crane Heidi , Elmaraghy Hany , DeLuca-Carter Louise , Buziqui Piruzeli Maria Lucia , Hu Chaoran , Pierce Evangeline , Agell Helena , Thaçi Diamant
Published: January 2025

Introduction: We report efficacy and safety of lebrikizumab (LEB) in long-term extension study ADjoin (NCT04392154) following up to 152 Weeks (W) of continuous LEB treatment with/without TCS. 
Methods: Patients in ADvocate1&2 who achieved per-protocol response (EASI 75 or IGA 0/1 without rescue) following 16W of LEB treatment were re-randomized 2:2:1 to LEB250mg Q2W, LEB250mg Q4W, or placebo (LEB withdrawal). Patients who completed W52 of ADvocate1&2 could enroll in ADjoin. Patients who completed 16W of ADhere could enroll into ADjoin; per-protocol LEB responders were randomized 2:1 to LEB250mg Q2W or Q4W. Intermittent use of topicals was allowed in ADvocate1&2 W16–52, topicals and short-term systemics were allowed in ADjoin. Data are reported for W16 LEB responders originating from ADvocate1&2 (N=181) and ADhere (N=86) who received LEB250mg Q2W or Q4W in ADjoin. Efficacy outcomes were assessed based on all collected data (as observed analysis) up to W100 of ADjoin (total 152W and 116W of LEB treatment for patients from ADvocate1&2 and ADhere, respectively). Safety was reported from ADjoin enrollment up to the data cut-off April 24, 2024.  
Results: In patients from ADvocate1&2, at W152 IGA 0/1 was maintained by 82.9% (34/41; Q2W) and 84.0% (42/50; Q4W) and EASI 75 was maintained by 90.5% (57/63; Q2W) and 94.1% (64/68; Q4W) of patients. In patients from ADhere, at W116 IGA 0/1 was maintained by 86.7% (26/30; Q2W) and 91.7% (11/12; Q4W) and EASI 75 was maintained by 94.9% (37/39; Q2W) and 90.9% (20/22; Q4W) of patients. EASI 90 was reported by 79.4% (50/63; Q2W) and 86.8% (59/68; Q4W) of ADvocate1&2 patients at W152 and 84.6% (33/39; Q2W) and 86.4% (19/22; Q4W) of ADhere patients at W116. 
During 100Ws of ADjoin, most adverse events (AE) reported were mild (29.2%, 78/267) or moderate (33.3%, n=89) in severity. Serious AEs were reported by 4.1% (n=11) of patients. There was one death due to natural causes in the ADhere Q2W arm. AEs leading to treatment discontinuation were reported by 2.6% (n=7) of patients.  
Conclusion: Efficacy outcomes were maintained long-term, up to 3 years of continuous LEB treatment, in both LEB250mg Q2W and Q4W arms. The safety profile of LEB in ADjoin was consistent with previous LEB studies in patients with moderate-to-severe AD.
Understanding the Experience of Healthcare Access and Health-Related Impacts among Individuals with Alopecia Areata
Authors: Heath Candrice , Anderson Lisa , Damani Shamsha , Bacci Elizabeth , Buchanan Andrew , Correll Julia , Pierce Evangeline , Constantine Melissa , Mitchell Beth , Chovatiya Raj
Published: January 2025

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Increased angiotensin converting enzyme (ACE2) level is associated with the cardiovascular risk in diabetes
Authors: Naveena Gurramkonda , Shivasekar Meera , Vinodhini V. M. , Nath Dinesh
Published: January 2025

Objectives:

Increased plasma angiotensin-converting enzyme 2 (ACE2) levels are associated with cardiovascular risk in diabetes and therapeutic targets. ACE2 is an endogenous regulator of the renin-angiotensin system and is important in various cardiovascular diseases (CVDs). This study aimed to investigate the association between increased ACE2 levels and cardiovascular risk in patients with type 2 diabetes mellitus (T2DM), particularly those with CVD.

Materials and Methods:

In this cross-sectional study, subjects were classified into 3 groups. Each Group has 87 individuals. Group I was considered as controls, Group II was considered as diabetes, and Group III was considered as diabetes with heart disease who attended the master health checkup, cardiology and general medicine OP in the tertiary care centre. The serum ACE, ACE2, oxidized-low-density lipoprotein (ox-LDL), and highly sensitive c-reactive were examined using the enzyme-linked immunosorbent assay technique, and the lipid levels were measured using the AU 480 (Auto analyser).

Results:

The study found that mean plasma ACE, ACE2, ACE/ACE2 ratio, ox-LDL, and high-sensitivity-C-reactive protein (hs-CRP) levels were significantly higher in group III than compared to group II and group I (P < 0.001). A significant correlation was observed between ACE2, ACE, ACE/ACE2 ratio, hs-CRP, and ox-LDL in patients with group III. Linear regression analysis showed a strong association of ACE2 with hs-CRP, ox-LDL and ACE.

Conclusion:

The study concludes that increased ACE2 levels may be associated with the risk of CVD in T2DM, especially in those with coronary heart disease. These findings suggest the possibility of independent risk assessment in diabetic patients.
SMARANDACHE ANTI ZERO DIVISORS
Authors: Hassan Rebin M. , Awla Suham H.
Published: January 2025

In this paper, we study and discuss the concept of Smarandache anti zero divisor (SAZD) element of the ring  and the group ring , where  is a cyclic group of order  generated by . Moreover, we introduce and discuss the concept of SAZD ideal of the ring . Some results related to the given concepts are proved in detail. Accordingly, a Computer Algebra System (GAP) is used to verify the results of this study
WEB VULNERABILITIES DETECTION USING A HYBRID MODEL OF CNN, GRU AND ATTENTION MECHANISM
Authors: Ali Sarbast H. , Mohammed Arman I. , Mustafa Sarwar MA. , Salih Sardar Omar
Published: January 2025

The frequency of cyber-attacks has been rising in recent years due to the fact that startup developers have failed to overlook security issues in the core web services. This stated serious concerns about the security of the web. Therefore, this paper proposes a hybrid model built on the base of Convolutional Neural Networks (CNN), Gated Recurrent Units (GRU) and an attention mechanism to detect vulnerabilities in application code. Particularly, the model can help detect attacks based on Structured Query Language Injection (SQLi), Cross-Site Scripting (XSS), and command injection. When using the dataset SXCM1, our model achieved 99.77%, 99.66% and 99.63% for training, validation and testing, respectively. The results obtained on data from the DPU-WVD dataset are even better because it was 99.97%, 99.98% and 99.99% for training, validation and testing, respectively. These results significantly outperform the state-of-the-art models and can strongly identify vulnerabilities in web applications. Through training, on both the SXCM1 and DPU-WVD datasets, the model achieved an accuracy rate of 99.99%. The results show that this combination model is highly effective at recognizing three vulnerability categories and surpasses cutting-edge models that usually specialize in just one type of vulnerability detection.
Formation of a system of economic education in the Sakha Republic (Yakutia)
Authors: Popov A. A. , Naberezhnaya A. T. , Petrova N. I.
Published: January 2025

In the year of the ninetieth anniversary of higher education in the Sakha Republic (Yakutia), it is necessary to turn to the origins of the formation of economic education in the republic, to study its current trends and development prospects. To achieve the strategic goals and objectives of the Russian Federation, specialists with economic and financial competencies are needed, which causes a high degree of urgency of the problem. The opening of the Yakut State Pedagogical Institute in 1934 and the Yakutsk State University in 1956 laid the foundations for economic education in our republic. This article defines the stages of formation of economic education in the Sakha Republic (Yakutia), training of financial and economic personnel for the effective functioning of the national economy. In a short historical period of time, Yakutia has passed the path of formation not only of educational institutions of various levels, but also of the creation of a higher education system as an important factor of social and economic development. Economic education is an integral, important part of higher education. The purpose of modern economic education is to form a high level of economic thinking and professional competencies. The level of competitiveness of the modern economy is largely determined by the quality of economic education, which creates the foundation for the growth of well-being and economic development. The article uses a set of quantitative and qualitative research methods: the study of scientific literature, regulatory legal documents; statistical data in the field of economic education, analytical materials, etc.
An ontological model of the reproduction system of a mineral resource asset
Authors: Dadykin V. S. , Dadykinа O. V.
Published: January 2025

One of the urgent problems in developing the subsoil mineral resource potential is the lack of reliable information on the volume of forecasted resources and the potential possibility of their transfer to conditional reserves for some types of mineral raw materials. The heterogeneity and diversity of information sources sometimes makes it impossible to create a model of a single information repository with its attributes and connections. The traditional approach to organizing an information storage system based on a relational database cannot be applied in this situation. Therefore, it is urgent to find an alternative to both the data storage system itself and the approaches that are used in its filling and updating. We propose to use an ontological model to solve this problem, as a way to organize a storage system and systematize heterogeneous sources of information. At the same time, taking into account a fairly large number of alternative options for constructing an ontological model, we propose to base it precisely on the concept of mineral resource potential.
Comparison of the number of nano-sized particles in blood plasma and on the erythrocytes surface using scanning electron microscopy in a cervical cancer patient
Authors:   Yakut Science Centre of Complex Medical Problems (YSC CMP), Yakutsk, Ru, Kononova I.V. , Mamaeva S.N. ,   PhD in in Physical and Mathematical Sciences, associate professor, head of department of General and Experimental Physics of PhTI NEFU
Published: January 2025

To explain the more productive isolation of HPV DNA from the blood component compared to plasma in cervical cancer patients, using scanning electron microscopy images of venous blood were studied. It was revealed that there are more nanosized bioparticles on the erythrocytes surface than in plasma. It has been suggested that among them there may be tumor extracellular vesicles carrying HPV DNA. To confirm that the erythrocyte fraction of blood is a more productive biological sample for isolating HPV DNA, continued studies are needed.
Keywords: human papillomavirus, screening, extracellular vesicles.
Possibilities of controlling bilateral tonic-clonic seizures using тthe application EpiTapp® for resistant epilepsy with the development of arteriovenous malformation
Authors:   Candidate of Medical Sciences, Associate Professor of Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk, Narodova E.A. , Schnaider N.A. ,   Doctor of Medical Sciences, Professor, head of Scientific Research, Deputy Head of the Institute of Personalized Psychiatry and Neurology of the Federal State Budgetary Institution Bekhterev National Medical Research Centre for Psychiatry and Neurology of the Ministry of Health of the Russian Federation, St. Petersburg, Erakhtin E.E. ,   neurosurgeon of Karpovich Krasnoyarsk Interdistrict Clinical Hospital of Emergency Medical Сare, Narodov A.A. ,   MD, Professor, Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of the Russian Federation
Published: January 2025

Patients with drug-resistant epilepsy (DRE) due to an arteriovenous malformation (AVM) located in a functionally significant area of the brain experience a significant decrease in quality of life and require additional non-drug rehabilitation methods aimed at controlling epileptic symptoms.
Aim. To present a clinical observation of the use of the Epi-Tapp® application in a 29-year-old patient with an AVM. Materials and methods. We used the author's wrist tapping method EpiTapp® (RF patent No. 2606489 dated January 10, 2017). Results. Using the EpiTapp® application allowed a 29-year-old man with an AVM to reduce the severity and duration of focal seizures in 85% of cases and prevent secondary bilateral transformation of incipient bilateral tonic-clonic seizures in more than 50% of cases. Conclusions. This clinical case demonstrates the possibility of effectively using the EpiTapp® application in a patient with drug-resistant epilepsy as an element of a rehabilitation program aimed at controlling epileptic seizures.
Keywords: epilepsy, wrist tapping, EpiTapp®, rehabilitation.
Ruthenocenoporphyrinoids - π-Conjugation Transmitted Across 1,3-Substituted Ruthenocene
Authors: Berlicka Anna , Walczak Aleksandra , Białek Michał , Ślepokura Katarzyna , Chmielewski Piotr , Latos-Grażyński Lechosław
Published: January 2025

Synthesis of ruthenocenoporphyrinoids, wherein the [RuCp*]+ moiety coordinates to the cyclopentadienyl π-surface of the 21-carba-23-selenaporphyrin macrocyclic platform has been developed. The NICS 2D maps and EDDB plots gave an insight into the aromaticity and effectiveness of π-conjugation across 1,3-substituted ruthenocene in obtained hybrid molecules.
Magnetic Field-Assisted Fe Nanowire Conformable Aerogels Galvanically Displaced to Cu and Pt for 3-Dimensional Electrode Applications
Authors: Calabro Rosemary L. , Longstaff Garret L. , Tang Edward M. , Xiao Veronika M. , Zammit Alexa S. , Zhang Felita W. , Nagelli Enoch A. , Chapman Peter H. , Lawton Timothy J. , Losch Anchor R. , Palmer Jesse L. , Ciampa Alexander D. , Burpeau Ian Z. , Lucian Veronica M. , Mandes Galen T. , Bartolucci Stephen F. , Maurer Joshua A. , Burpo F. John
Published: January 2025

There is an increasing need for free-standing, conformal electrodes for practical energy storage devices. To address this, we demonstrate the magnetic field-assisted synthesis of interpenetrating Fe nanowire (FeNW) gels without the use of templates or composite scaffold material over a range of magnetic fields. In either a wet gel or supercritical dried state as an aerogel, the FeNWs may be pressed into thin or conformal films. Varying the applied magnetic field strength with a solenoid during chemical synthesis resulted in increased nanowire length and local orientation of the FeNWs with increasing magnetic field strength, with approximately 80 nm diameters across field strengths of 0-150 mT. Flowing K2PtCl4 or CuSO45H2O solutions through the wet iron gels to achieve the near complete galvanic displacement of iron to the more noble [PtCl4]2- and Cu2+ ions resulted in either platinum nanotubes (PtNTs) or copper nanowires (CuNWs) while maintaining a percolating network structure. Similar to the FeNW gels, the PtNT and CuNW gels were able to be supercritical dried and/or pressed into thin or conformal electrode films. CuNW and PtNT films demonstrated good potential as capacitive and oxygen reduction reaction electrodes, respectively. The magnetic field assisted synthesis of ferromagnetic iron nanowires offers a simple, rapid and tunable method, that when combined with galvanic displacement with more noble metal ions, may enable a wide range of metal, alloy, and multi-metallic nanowires and nanotubes for energy storage, sensing and catalytic applications.
Simplified tuning of long-range corrected time-dependent density functional theory
Authors: Mandal Aniket , Herbert John
Published: January 2025

Range-separated hybrid functionals have dramatically improved the description of charge-transfer excitations in time-dependent density functional theory (TD-DFT), especially when the range-separation parameter is adjusted in order to satisfy the ionization energy (IE) criterion, eHOMO = –IE. However, this "optimal tuning" procedure is molecule-specific, inconvenient, expensive for large systems, and problematic in extended or periodic systems. Here, we consider an alternative procedure known as global density-dependent (GDD) tuning, which sets the range-separation parameter in an automated way based on properties of the exchange hole. In small molecules, we find that both IE- and GDD-tuned functionals afford remarkably similar TD-DFT excitation energies, for both valence and charge-transfer excitations. However, GDD tuning is more efficient and is well-behaved even for large systems, providing a black-box solution to the optimal-tuning problem that can replace IE tuning for many applications of TD-DFT.
Phase-migrating Z-scheme charge transportation enables photoredox catalysis harnessing water as an electron source
Authors: Itagaki Ren , Nakada Akinobu , Suzuki Hajime , Tomita Osamu , Chang Ho-Chol , Abe Ryu
Published: January 2025

Z-schematic photocatalytic reactions are of considerable interest because of their potential for application to reductive molecular conversions into value-added chemicals using water as an electron source. However, most demonstrations of Z-scheme photocatalysis have far been limited to overall water splitting. In particular, it has been basically impossible to couple the reduction of “water-insoluble compounds” with water oxidation by conventional Z-scheme systems in aqueous solution. In this work, an unconventional Z-scheme electron transportation system with a “phase-migrating” redox mediator is constructed that enables photocatalytic conversion of water-insoluble compounds by using water as an electron/proton source.
Study on the Effect of Percutaneous Coronary Intervention in the Treatment of Chronic Coronary Syndrome
Authors: Zhao Yingxin
Published: January 2025

Objective: To analyze the clinical effect of percutaneous coronary intervention in the treatment of chronic coronary syndrome. Methods: 120 cases of chronic coronary syndrome patients who received inpatient treatment in a hospital from July 2023 to June 2024 were selected as the object, and were divided into the control group and the observation group using the mean score method, each with 60 cases, the control group was treated with conventional medications (aspirin, carbamazepine, β-receptor blockers, angiotensin-converting enzyme inhibitors, statin and other medications), and the observation group was treated with percutaneous The observation group implemented percutaneous coronary intervention based on this treatment, comparing the therapeutic effects of the two groups. Results: The treatment efficiency of the observation group (98.33%) was significantly higher than that of the control group (86.67%), and the difference was statistically significant (P < 0.05); before treatment, the IVPWTd and LVEDd indexes of the patients in the control group and the observation group were (10.39 ± 0.86) mm, (55.36 ± 5.67) mm and (10.41 ± 0.78) mm, (56.01 ± 6.80) mm, respectively. The difference was not statistically significant (P > 0.05); after 3 weeks of treatment, all the indexes of the two groups decreased significantly, respectively (9.76 ± 0.62) mm, (53.28 ± 5.63) mm and (8.56 ± 0.49) mm, (49.65 ± 5.47) mm, and the observation group was significantly lower than the control group, and the difference was statistically significant (P < 0.05). In the control group, 3 cases of arrhythmia and 2 cases of coronary artery spasm occurred during the treatment period, and 1 case each of residual cardiac insufficiency, acute thrombosis, chronic renal impairment, and cardiogenic death, with a total incidence rate of 15%, while in the observation group, only 1 case of arrhythmia and 1 case of coronary artery spasm occurred, with a total incidence rate of 3.33%, and the difference between the groups was statistically significant (P < 0.05). Conclusion: Percutaneous coronary intervention for the treatment of chronic coronary syndrome combined with renal disease is effective, can significantly improve the level of patients’ left ventricular function and reduces the risk of related complications, and is recommended to be popularized and applied in the clinic.
Clinical Effect of Buyang Huanwu Decoction Combined with Acupuncture in Treating Cerebral Infarction Sequelae
Authors: Lu Zhicheng
Published: January 2025

Objective: To explore the clinical effect of Buyang Huanwu Decoction combined with acupuncture in treating cerebral infarction sequelae. Methods: In this study, 80 patients with cerebral infarction sequelae admitted to the hospital from April 2022 to March 2024 were selected and divided into a control group (n = 40) and a combined group (n = 40) according to different treatment regimens. The control group received acupuncture treatment alone, while the combined group received Buyang Huanwu Decoction treatment based on the control group. The clinical effects, physical indicators, and adverse reactions of the two groups were compared and observed 3 months after treatment. Results: After treatment, the clinical efficacy of the combined group (92.50%) was significantly higher than that of the control group (72.50%) (p < 0.05). The physical indicators of the combined group were significantly better than those of the control group (p < 0.05). Additionally, the combined group had fewer adverse events than the control group (p < 0.05). Conclusion: The combination of Buyang Huanwu Decoction and acupuncture has significant efficacy in treating cerebral infarction sequelae. It can effectively contain disease progression, reduce adverse events, and significantly improve patients’ physical indicators. This treatment approach has clinical promotional value.
Advances in Identification and Clinical Management Strategies of Nitrate Resistance
Authors: Zhao Zheng , Zhang Qingshan , Sun Li , Feng Xue , Li Xiaolu
Published: January 2025

Nitrates are widely used in acute and critical diseases such as angina pectoris, acute heart failure and hypertension. However, there are still many problems caused by the non-standard use of these kinds of drugs and drug resistance, which need to be paid attention to in clinical practice, scientific research, and patient education. This article mainly reviews the identification and clinical treatment strategies for nitrate resistance.
The Impact of Improved and Refined Education on Anxiety After Interventional Surgery for Cerebrovascular Disease
Authors: Wang Cheng , Zhao Haibo , Zuo Huirong
Published: January 2025

Objective: To explore the impact of modified and refined health education on anxiety among patients undergoing interventional therapy for cerebrovascular diseases. Methods: Eighty patients with cerebrovascular diseases who underwent interventional therapy at the hospital from June 2023 to June 2024 were selected as the study subjects. They were divided into an observation group and a control group according to the random number table method, with 40 patients in each group. The control group received conventional health education, while the observation group received modified and refined health education. The Self-Rating Anxiety Scale (SAS) scores were compared between the two groups after the procedure. Results: There were no significant differences between the two groups in terms of gender, age, education level, and duration of illness (P > 0.05). The SAS score in the observation group was significantly lower than that in the control group, showing a highly significant correlation (P < 0.001). Conclusion: Modified and refined health education can effectively reduce anxiety levels among patients undergoing interventional therapy for cerebrovascular diseases and improve their quality of life, making it worthy of clinical promotion and application.
Analysis of a Case of Immune-Related Myocarditis Combined with Myasthenia Gravis and Liver Injury Induced by Tislelizumab
Authors: Xu Hongyan , Han Rubing , Zhao Yunjie , Zheng Meicun , Zhang Xia
Published: January 2025

Immune checkpoint inhibitors (ICIs) have demonstrated significant advantages and potential in tumor immunotherapy, but immune-related adverse events (irAEs) are becoming increasingly important safety issues. This article analyzes and discusses a case of a patient with esophageal cancer who developed bilateral lower limb weakness, bilateral ptosis, loss of appetite, nausea, and vomiting after four cycles of treatment with tislelizumab. The patient was considered to have immune-related myocarditis, myasthenia gravis, and liver injury involving multiple organs caused by tislelizumab treatment. As multi-organ damage caused by tislelizumab is rarely reported domestically and internationally, this article will analyze and discuss domestic and foreign literature, hoping to provide some help to clinicians who subsequently use tislelizumab.
The Problems and Countermeasures of Implementing Educational Discipline for Rural Teachers
Authors: Chen Yao , Chen Qianhong
Published: January 2025

Educational discipline has received widespread attention in both practical and academic fields in recent years. By using the event sampling observation, multiple incidents of teacher education discipline were collected in a rural primary school in C County, H Province of China within one semester. Through analysis, the educational discipline in the school included three kinds: verbal discipline, behavioral discipline, and psychological discipline. Through interviews with relevant teachers and students, it was found that teachers have an insufficient understanding of relevant regulations, an inaccurate understanding of the connotation of educational discipline, a fear of using educational discipline, and an unclear basis for educational discipline when implementing it. The main reasons include that the school’s promotion of educational discipline policies is not sufficient, teachers lack active learning of relevant laws and regulations, some parents have misunderstandings about the implementation of educational discipline for teachers, and social public opinion has also had a negative impact. It suggests that schools should strengthen training and improve management systems, while teachers should strengthen learning and enhance cooperation in educating students. In addition, parents should enhance their identification and share the responsibility of educating children, and society should optimize the environment and enhance social awareness.
Research on Credit System for Student Clubs in Colleges and Universities
Authors: Liu Tong
Published: January 2025

The promotion of college credit system has brought new development opportunities and challenges for the construction of college students’ associations. Colleges and universities should actively innovate the application path of credit system based on the current situation of college student associations, analyze various problems existing in the application of college student associations credit system, and find the corresponding optimization strategies. Based on this, the study will conduct an in-depth discussion on the above issues in this article, hoping to provide some reference and help for readers.
Research on the Construction of Virtual Reality Technology Major Course System
Authors: Mu Wangang
Published: January 2025

Along with virtual reality technology is widely used in all walks of life, China’s social and economic development urgently needs high-quality innovative, and compound virtual reality technical personnel. In this context, as the main front of training virtual technical talents, universities are urgently required to promote the innovative construction and deepening reform of the virtual reality technology curriculum system, and on this basis to promote the deep integration of the industrial chain, innovation chain, discipline chain and talent chain. Based on this, combined with the background of the optimization of the curriculum system of virtual reality technology major in colleges and universities under the new situation, this paper discusses the specific optimization path by elaborating the relevant optimization ideas to improve the quality of talent training for virtual reality technology majors.
Multi-factor Synergy and Optimization Strategies for the Business Model of Private Higher Education Institutions’ Innovation and Entrepreneurship Incubators
Authors: Ye Zuolong
Published: January 2025

Globalization and advancements in science and technology foster innovation and entrepreneurship. Although national strategies provide substantial support, innovation, and entrepreneurship incubators in private colleges and universities face challenges such as insufficient funding and a lack of talent. This study enhances the theoretical framework of innovation and entrepreneurship education and broadens the application of business model theory. It examines the current state of innovation and entrepreneurship incubators in private universities, using the Maker Dream Workshop at Guangzhou University of Science and Technology as a case study. Key aspects such as value proposition, resource allocation, and profit models are analyzed. Additionally, challenges in multi-factor collaboration, including internal synergy barriers and external coordination difficulties, are identified. Optimization strategies are proposed, such as establishing an information-sharing platform, optimizing resource allocation mechanisms, improving benefit distribution systems, developing a long-term mechanism for industry-university-research cooperation, strengthening communication with the government, and encouraging participation from investment institutions. Furthermore, the study outlines the strategic measures required to ensure the sustainable development of innovation and entrepreneurship incubators in private colleges and universities.
The Construction of a Blended English Teaching Model for Vocational Education Based on Mobile-Assisted Language Learning (MALL)
Authors: Gao Junxia , Tan Ye
Published: January 2025

With the rapid development of mobile internet technology, mobile learning has emerged as a mainstream learning method for the new generation of students. Based on the “Fishpond Theory,” this paper proposes a blended learning model for vocational English education, utilizing the WeChat platform on smartphones. The objective is to integrate the benefits of traditional classroom teaching with mobile learning to enhance students’ autonomous learning abilities and improve their English learning outcomes. This paper reviews relevant theories and literature, explaining the basic concepts of Fishpond Theory, Mobile-Assisted Language Learning, and blended learning. It further designs a three-stage teaching model construction path, encompassing front-end analysis, activity and resource design, and teaching model evaluation, tailored to the characteristics of vocational English education. Through the WeChat platform’s resource distribution, personalized learning support, and online-offline interactive feedback, teachers can effectively guide students toward autonomous and in-depth learning. The findings indicate that this model significantly increases student motivation and engagement. However, in practice, it is crucial to strengthen the cultivation of students’ learning habits and the guidance and supervision provided by teachers.
An Analysis of College Music Education Reform Based on the Perspective of National Culture Inheritance
Authors: Weng Mengnan
Published: January 2025

With the continuous development of the era, the inheritance of national culture has been paid more attention in the current education field. Therefore, as the main places of education, colleges and universities should also undertake the corresponding inheritance obligations and guide students to pay more attention to national culture. In this context, college music courses and other related content also need to be reformed and innovated from the aspects of educational philosophy, teaching content and teaching methods. At the same time, it is necessary to combine the actual teaching situation with the needs of national culture inheritance, so that it can be further developed in the new era. This paper mainly starts with the importance of college music education reform and the integration and development of national culture inheritance, and deeply analyzes the reform path of college music education based on the perspective of national culture inheritance, hoping to provide some new teaching ideas for relevant teachers to make contributions to the reform and practice of college music education.
Research on the Integration of Ideological and Political Education in the Teaching of Cross-Border E-commerce Practice
Authors: Hou Ranran
Published: January 2025

The study of higher education stage is not only for students to master professional knowledge, and consolidate professional skills, but also need to have good professional ethics, with a sense of social responsibility and innovative thinking, which is needed in all fields. Global economic integration and the development of information technology, speed up the development of cross-border e-commerce, combined with social needs and higher education needs, to make the field of cross-border e-commerce in the new social background, it is important to pay attention to the effectiveness of ideological and political education. Especially with the proposal and construction of the current curriculum ideology and politics, colleges and universities are required to reform the professional courses of cross-border e-commerce to meet the actual needs of talents. Based on colleges and universities, this paper studies the integration of Cross-Border E-commerce Practice courses and ideological and political education and discusses the teaching mode, teaching content, teacher team, and teaching evaluation respectively for reference.