bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessment of Psycho-emotional Distress Due to Age, Body Mass Index, and Marital Status in Polycystic Ovary Syndrome in North Indian Population
Authors: Tabassum Fauzia , Sinha Hemali Heidi , Dhar Kavita , Jyoti Chandra , Akhtar Md Sayeed , Chopra Vipender Singh
Published: December 2020

Objectives: Polycystic ovary syndrome (PCOS) is a multifaceted endocrine disorder in reproductive age having a greater impact on health-related quality of life (HRQOL). The aim of this study was to find out PCOS demographics and its related HRQOL effects for improving psychological understanding in disease management. Materials and Methods: A prospective questionnaire-based study was conducted for a period of twelve months at All India Institute of Medical Sciences, Patna, India. The data of 100 PCOS cases were collected about socio-demographic status, clinical history, and dietary intake. Then, a validated PCOS questionnaire (PCOSQ) was used to observe the impact of PCOS symptoms on patients’ HRQOL. Results: The overall 57% and 48% of PCOS cases belonged to the age range of 20-30 years and had a body mass index (BMI) of >25-30, respectively. Based on the results, a significant difference was observed in the mean score of PCOSQ vs. marital status in PCOS cases with respect to emotion (P=0.039), body weight (P=0.002), and infertility (P=0.001). Furthermore, the result showed a significant difference in the domain of emotion (P=0.008), body hair (P=0.035), body weight (P<0.001), and infertility (P=0.018) among BMI group, and a high score was observed in the BMI group <18 in comparison to the other groups of BMI. Conclusions: In general, our findings indicated that infertility, emotions, and BMI had extremely higher impacts on the HRQOL of women suffering from PCOS although their educational status failed to affect HRQOL.
The Relationship Between Sexual Self-concept and Mental Body Image in Women With Breast Cancer
Authors: Gooran Safieh , Simbar Masoumeh , Hajian Sepideh , Nazarpour Soheila , Nasiri Malihe , Martin Jeno
Published: December 2020

Objectives: Breast cancer is the most common malignancy in women. In addition, it is the most mentally powerful cancer in women due to affecting the most important female sexual part. Patients with breast cancer experience problems in their marital relationship because of their disrupted mental image and sexual relations. In this regard, this study was conducted to investigate the relationship between sexual self-concept and mental body image in women with breast cancer. Materials and Methods: This descriptive cross-sectional study was conducted on a sample of 120 women with breast cancer. Using a convenience sampling technique, patients were selected from among those hospitalized in the selected hospitals of Tehran in 2018. Data were collected using demographic details, the Multidimensional Sexual Self-Concept Questionnaire (MSSCQ), and the Fisher’s Body Focus questionnaire. Finally, the data were statistically analyzed in SPSS-21. Results: According to the descriptive and analytical statistics, women with breast cancer obtained the highest scores in avoiding risky sex and sexual problem prevention while the lowest scores in terms of sexual preoccupation. Based on the results, there was no disruption in the body image of any of the examined women. Eventually, a significant correlation was observed between sexual self-concept and body image (P<0.001, r=0.4). Conclusions: In general, body image has a positive relationship with sexual self-concept in women with breast cancer and is considered an important predictor of sexual health and behaviors of this group. Accordingly, psychological interventions, along with midwifery and sexual consultations offered by trained personnel can help empower these patients.
The Expression of miR-31 and its Target Gene FOXP3 in Recurrent Implantation Failure Patients
Authors: Azarpoor Azita , Ardeshirylajimi Abdolreza , Mohammadi Yeganeh Samira , Pour matrood Elham , Dehghan Zeinab , Salehi Mohammad
Published: December 2020

Objectives: Endometrial receptivity is a complex event that occurs during the midluteal phase of the menstrual cycle known as the "window of implantation". During this period, the endometrium develops characteristics that allow the adhesion and invasion of the embryo to the uterine epithelium. Accordingly, the expressions of miR-31 and its target gene were evaluated to study the effect of miR-31 on FOPX3 gene expression in recurrent implantation failure (RIF) patients and normal fertile women. More precisely, the aim of this study was to understand the expression of miR-31 as one of the important regulators of the FOXP3 gene in the endometrium of RIF patients versus receptive endometria from fertile patients. Materials and Methods: This case-control study was conducted on 20 endometrial tissue samples of normal fertile women and RIF patients in order to evaluate miR-31 and its target gene expression. Results: According to the results of this study, a significant difference existed between RIF patients and normal fertile women (control group). The expression of the FOXP3 gene was more significant in the control group. miR-31 was also significantly expressed, which was due to the endometrial immunological disorder leading to the decreased expression of its target gene (FOXP3). Conclusions: In general, implant abnormalities and recurrent abortions were observed in RIF patients due to the decreased expression of the FOXP3 gene resulting from the inhibitory effects of miR-31.
Relation of the Renal Artery Color Doppler With the Umbilical Artery and Amniotic Fluid Index in Fetuses Affected by Intrauterine Growth Retardation
Authors: Shoari Neda , Abbasalizadeh Shamci , Faridiazar Zahra , Mousavi Sanaz , Sahhaf Farnaz
Published: December 2020

Objectives: This study was performed to investigate the relationship between the renal artery color Doppler with the umbilical artery and amniotic fluid index (AFI) in fetuses affected by intrauterine growth retardation (IUGR). Materials and Methods: This was a descriptive cross-sectional diagnostic study and the target population included pregnant mothers who were diagnosed to have fetuses with IUGR referring to the Al-Zahra treatment center in Tabriz. At least 40 samples were referred between October 2019 and May 2020. The patients were evaluated using the transabdominal ultrasound of the umbilical artery and fetal renal artery, and then using the color Doppler values of the umbilical artery and fetal renal artery. Results: The present research was performed on 40 pregnant females with an IUGR fetus with umbilical artery percentile upper that 95% whose minimum to maximum age range was 22-38 years. There is no relationship between umbilical artery and renal artery color Doppler. In addition, umbilical artery color Doppler is not related to amniotic fluid, also renal artery color Doppler demonstrated no significant correlation with amniotic fluid index. Conclusions: Based on our results, the PI of the umbilical artery had no significant correlation with that of the renal artery. In addition, there was no significant correlation with the PI of the renal artery and AFI.
Prevalence and Risk Factors for Low Back Pain in Primiparous Women Visiting Maternity Hospitals During Different Months of Pregnancy
Authors: Nazari Behrooz , Zamani Esfahlani Mehrdad , Dorosti Abbasali , Mirzaei Farhad
Published: December 2020

Objectives: Pregnancy is one of the pleasant periods of a woman’s life that turns into a bitter experience by common complications such as low back pain (LBP). Due to prevailing climatic conditions in Iran and the harmful social norms concerning Iranian women, the present study aimed to investigate the prevalence of pregnancy-related LBP and its influencing factors during different months of pregnancy. Materials and Methods: This descriptive cross-sectional study was conducted in 2019 on 550 pregnant women for LBP who were eligible based on the inclusion criteria. The research instruments were a demographic questionnaire, a LBP examination, and the visual analog scale (VAS). The obtained data were analyzed using the chi-square test, the independent t test, and multiple logistic regression in SPSS 20, and a P<0.05 was considered statistically significant. Results: The prevalence of LBP was 67.27%, and the most important factors influencing pregnancy-related LBP were maternal age (OR=950, P<0.008), gestational age (OR=1.023, P=0.015), body mass index (OR=802, P=0.045), duration of sitting (OR=1.812, P=0.036), and the duration of standing (OR=1.625, P=0.042). Conclusions: Overall, there was a high prevalence of pregnancy-related LBP in primiparous women in the present study and its predisposing risk factors included advanced maternal age, obesity, and low level of ability to sit and stand for a long time.
The Effect of Interval Training on Oxidative Stress Indices Among Women in Preterm Labor Underwent Coronary Artery Bypass Graft
Authors: Hashemzadeh Khosrow , Dehdilani Marjan , Khanbabayi Gol Mehdi
Published: December 2020

Objectives: Oxidative stress indices are one of the factors that cause and exacerbate cardiovascular diseases in postpartum women, which can be changed with interval training. Therefore, the current study aimed at investigating the effect of interval training on oxidative stress indices among women in preterm labor undergoing the coronary artery bypass graft (CABG). Materials and Methods: This randomized clinical trial was conducted on 21 participants (the sample size was determined based on a similar study) from December 2018 to May 2019 at Shahid Madani hospital of Tabriz, Iran. After the random allocation of subjects to the training (n=11) and control (n=10) groups, demographic information was collected and their physical activity level was assessed using the Kaiser physical activity survey before and after the intervention. In addition, the levels of oxidative stress indices were measured 24 hours before and after the intervention using the blood sample. The participants completed an eight-week invention including 24 one-hour sessions according to the available protocol. Finally, data were analyzed by means of statistical tests such as the Shapiro-Wilk, Leven, and Student’s t-test at a significant level of <0.05. Results: The effect of the aerobic exercise program on body weight loss, as well as body mass index (BMI) and body fat percentage changes was significant in the training group (P=0.011, P=0.004, and P=0.001, respectively). Based on the results, the serum and urine levels of 8-hydroxy-2-deoxyguanosine reduced significantly after the completion of the intervention (P=0.002 and P=0.001, respectively) in the training group. Conclusions: In general, aerobic exercise after CABG decreased the fat percentile, BMI, and oxidative stress indices in the subjects. Thus, these trainings could reduce oxidative stress indices by increasing tissue metabolism and oxygen consumption.
The Association Between Vaginal Candidiasis and Health-promoting Lifestyle in Iranian Women: A Cross-sectional Study
Authors: Azhrak Parvin , Kamalifard Mahin , Mirghafourvand Mojgan , Khedri Soleiman , Hasanpour Shirin
Published: December 2020

Objectives: Vulvovaginal candidiasis is the second most common gynecological infection in the world that can bring about unfavorable consequences for the health and life of the women of reproductive age. Accordingly, the purpose of this study was to determine the prevalence of vulvovaginal candidiasis and its relationship with the health-promoting lifestyle in Boukan, Iran. Materials and Methods: This cross-sectional study was conducted with the participation of 320 married women aged 15-49 years who referred to all health centers of Boukan. The subjects were selected using a convenience sampling technique from October 2018 to March 2019. Written informed consent was obtained from the participants who were then asked to complete a demographic questionnaire and the Health- Promoting Lifestyle Profile-II (HPLP-II). Finally, the data were analyzed in SPSS, version 24. Results: A total of 124 women (38.8%) had vulvovaginal candidiasis, and the total mean (standard deviation) score of health-promoting lifestyle was 2.4 (0.2) from the possible range of 1-4. None of the demographic characteristics and vulvovaginal candidiasis were significantly related based on the results (P<0.05). The highest (2.8±0.3) and lowest (1.6±0.4) mean scores belonged to "nutrition" and "physical activity" subdomains, respectively. In addition, no statistically significant relationship was found between vulvovaginal candidiasis and the total mean score of health-promoting lifestyle and its subdomains (P>0.05). Conclusions: In general, more than one-third of the participants had vulvovaginal candidiasis. Eventually, the infection had no statistically significant relationship with any of the characteristics of demographic information and health-promoting lifestyle.
Microbiome of the Uterus in Women With Unsuccessful in Vitro Fertilization Attempts
Authors: Vladislavovna Barinova Viktoriya , Borisovna Kuznetsova Natalya , Olegovna Bushtyreva Irina , Mikhailovna Sokolova Kristina , Evgenievich Polev Dmitry , Vladimirovich Aseev Mihail , Valerievna Dudurich Vasilisa
Published: December 2020

Objectives: This study aimed to investigate the peculiarities of the uterine microbiome in the case of infertility and repeated in vitro fertilization (IVF) failures. Accordingly, the microbiome of the uteri of 22 women with 2 or more IVF failures (first group) and 20 healthy women (second group) was analyzed in this study. Materials and Methods: The samples of uterine microbiomes were collected 7 days after the luteinizing hormone elevation, which was determined by the urine test. All measures were taken to avoid sample contamination. Finally, the massively parallel sequencing of the 16S ribosomal RNA gene was done in every uterine sample. Results: The analysis of the mean relative abundance of various microorganisms in the uterine microbiome showed that women with infertility had higher microbiological diversity and variability compared to healthy women. Eventually, the mean relative abundance of the Lactobacillus genus comprised 34.4% and 63.0% in the first and second groups, respectively. Conclusion: In general, the presence of Lactobacillus in the uterine microbiome could be considered a favorable factor for good reproductive outcomes and successful IVF programs.
Approximative characteristics of the Nikol'skii-Besov-type classes of periodic functions in the space $B_{\infty,1}$
Authors: Fedunyk-Yaremchuk O.V. , Hembars'kyi M.V. , Hembars'ka S.B.
Published: December 2020

We obtained the exact order estimates of the orthowidths and similar to them approximative characteristics of the Nikol'skii-Besov-type classes $B^{\Omega}_{p,\theta}$ of periodic functions of one and several variables in the space $B_{\infty,1}$. We observe, that in the multivariate case $(d\geq2)$ the orders of orthowidths of the considered functional classes are realized by their approximations by step hyperbolic Fourier sums that contain the necessary number of harmonics. In the univariate case, an optimal in the sense of order estimates for orthowidths of the corresponding functional classes there are the ordinary partial sums of their Fourier series. Besides, we note that in the univariate case the estimates of the considered approximative characteristics do not depend on the parameter $\theta$. In addition, it is established that the norms of linear operators that realize the order of the best approximation of the classes $B^{\Omega}_{p,\theta}$ in the space $B_{\infty,1}$ in the multivariate case are unbounded.
COVID-19 pandemic and fiscal sustainability
Authors:   Institute for Economics and Forecasting, NAS of Ukraine, Stepanova Olena
Published: December 2020

The article deals with the impact of the COVID-19 pandemic on the financing of the health care system, and the main challenges to the stability of the financial mechanisms of post-pandemic health care development have been identified. The author substantiates the peculiarities of the crisis of health care financing in the conditions of the current pandemic, further economic recession and decreased fiscal sustainability. The global practice of fiscal response to the manifestations of the COVID-19 pandemic has been systematized and the volumes of the corresponding financing in the countries with insurance and budgetary systems of health care financing have been estimated. The article identifies mechanisms for the transformation and expansion of the fiscal space in the context of expanded financing of the growing need for medical care in the face of new epidemic risks in different countries. Most often, the expansion of a country's fiscal space is carried out by: redistributing the existing amount of government expenditure for health care and redirecting funding flows from financing certain types of medical care to financing programs to overcome and combat COVID-19; changes in the priority of government health expenditure to combat COVID-19 compared to other budget expenditures on the social sphere and economic development; and using national reserve funds and emergency funds. It has been found that in the field of health care, the vast majority of countries have reduced the economic and territorial deprivation of all population groups in access to the diagnosis and treatment of COVID-19. The author emphasizes the weaknesses of insurance based and decentralized health financing mechanisms to respond to the growing need for health care and financial stability during the pandemic. Substantiated the necessity to expand the fiscal space needed to cover the fiscal gap in Ukraine caused by the requirement to increase health care financing in response
Translation of the “Gospel of Luke” (1821) into Erzya: some features of noun morphology
Authors: Deviatkina Ekaterina M.
Published: December 2020

Introduction. This paper considers some features of noun morphology in the translation of the “Gospel of Luke” (1821) into the Erzya language, namely the indicators of such grammatical categories of the noun as number, case and the categories of possessiveness and definiteness. Analysis of old manuscripts is necessary, as it provides important information in the reconstruction of the language.
Materials and Methods. The text of the translation of the “Gospel of Luke” (1821) into Erzya, materials of the Erzya dialects were collected by the author during the expeditions to Samara region in 2011–2012. The analysis of the books on the topic of dialect features of the Erzya dialects were also used for the research. When working with the material, the morphological paradigms in the published part of the concordance of the “Gospel of Luke” (lingvodoc.ispras.ru) and the material obtained by the method of continuous sampling were compared with the data of modern dialects of the Erzya language.
Results and Discussion. It is shown that the indicators of the category of number of nouns in the text of the manuscript correspond to the affixes of the Central dialect and are used according to the same rules. The case system is different from the case system of the literary language, namely the semantics of some cases is represented by other case formants, postpositions, and other syntactic constructions. The index declension is represented by the formant -s’t’, and the possessive declension shows the numerical difference between the possessors in 1 and 3 persons singular.
Conclusion. The analysis of the language material allows to conclude that the translated text belongs to the Central dialect, which has its own distinctive features. At the same time, the final solution of the dialectal affiliation of the manuscript should be based on a comprehensive account not only of the material considered in the paper, but also, at least, on the results of further detailed analysis of the features of phonetics, morphology and vocabulary.
A costume in the funeral rituals of the Mari people
Authors: Pavlova Anzhelika N.
Published: December 2020

Introduction. Burial rites, which are a traditional object of research in archeology and ethnography, are one of most stable elements of ethnic culture. The costume and its individual elements took an important place in the funeral and memorial rites. The study of these rituals can reveal new aspects of the spiritual culture of the Mari people.
Materials and Methods. The work is based on the comparison of archaeological and ethnographic materials, culturogical approach, methods of semantic, cultural and anthropological research.
Results and Discussion. The reference of funeral and memorial rites to the passage rites determined the use of the elements of a wedding dress, including fur clothes and jewelry. The belt that served as a storage was an important part of the burial costume, as well as the sacrificial and ritual complexes of the ancient Mari tribes.
Conclusion. Application of a culturological approach to the research of the funeral rituals of the Mari people allowed to conclude that the costume substituted the deceased, served as the embodiment of a generic body that went back to the totem. The funeral costume, like the wedding one, assumed the use of ancient symbolic codes. The belt that completed the symbolic human body was an important burial costume. The belt served as a defense in the ancient Mari sacrificial ritual complexes, enhancing their association with the world tree.
Patriotic education as a basis for strengthening Russian national civic identity: experience of the Republic of Mordovia
Authors: Kazakova Marina N. , Napalkova Irina G.
Published: December 2020

Introduction. In modern Russia, patriotism is broadcast by the authorities as the only possible ideology of a democratic state, its national idea, which gives rise to many disputes and discussions within connotational boundaries: “love for the homeland lies outside states and nations – this is an initial, natural, genetic feeling” vs “the idea of sovereign patriotism can and should be the basis of the national idea of Russia”. The purpose of this publication is to consider the conceptual base and the activity of the formation of patriotic consciousness in the period 2012–2020 on the example of a separate subject of the Russian Federation – the Republic of Mordovia. Materials and Methods. The methodology was based on a retrospective analysis, an axiological paradigm, and a systematic approach. Case study was used among the applied methods. The Republic of Mordovia acted as a case, as it is a typical constituent entity of the Russian Federation related to agro-industrial regions, on the other hand as a national republic in which citizens of 119 nationalities live, while the national composition is dominated by Mordovians (Moksha, Erzya), Russians, Tatars. Results and Discussion. In the Republic of Mordovia, as well as in the Russian Federation as a whole, civic and patriotic education and the formation of patriotic consciousness of citizens is implemented through a program-targeted approach. This is expressed in a number of state programs, including “Development of Education in the Republic of Mordovia”, “Development of Culture and Tourism in Russia”, “Counteracting Drug Abuse and Illicit Trafficking”, “Harmonization of Interethnic and Interfaith Relations in the Republic of Mordovia”, etc., and there is a continuity in their adoption and prolongation. Effective vertical and horizontal interagency links have been created for their implementation. In recent years, individual civil society institutions, in particular, socially oriented non-profit organizations, have been actively involved in civic and patriotic education. The work also examines the activity component in the context of the analysis of individual events, graded by the authors for civic and patriotic, social and patriotic, heroic and patriotic and military and patriotic vectors. The problematic area remains the co-financing of state-funded programs in terms of the region’s obligations due to the accumulated problems in the budgetary sphere and, as a result, the highest debt burden of all the subjects of the Russian Federation. Conclusion. In nowadays Russia, the elements of civic-patriotic education are consistently implemented in the state educational, cultural, national, and youth policy. In the Republic of Mordovia, the implementation of patriotic themes is assessed as diversive and it has various formats. It is carried out according to civic and patriotic, socio-patriotic, heroic-patriotic, military-patriotic vectors.
Extended Cauchy–Schwarz Inequality and Its Application for the Two-Class Fisher Discriminant Analysis
Authors: Sablik Maciej , Stapor Katarzyna
Published: December 2020

We present the sufficient condition for a classical two-class problem from Fisher discriminant analysis has a solution. Actually, the solution was presented up to our knowledge with a necessary condition only. We use an extended Cauchy–Schwarz inequality as a tool.
Some Classes of Polynomials Satisfying Sendov’s Conjecture
Authors: Sofi Ghulam Mohammad , Ahanger Shabir Ahmad , Gardner Robert Bentley
Published: December 2020

In this paper, a relationship between the zeros and critical points of a polynomial p(z) is established. The relationship is used to prove Sendov’s conjecture in some special cases.
Morrey Spaces Related to Schrödinger Operators with Certain Nonnegative Potentials and Littlewood–Paley–Stein Functions on the Heisenberg groups
Authors: Wang Hua
Published: December 2020

Let be a Schrödinger operator on the Heisenberg group , where is the sublaplacian on and the nonnegative potential V belongs to the reverse Hölder class with . Here is the homogeneous dimension of . Assume that is the heat semigroup generated by. The Lusin area integral and the Littlewood–Paley–Stein function associated with the Schrödinger operator are deﬁned, respectively, by

where

and

Where is a parameter. In this article, the author shows that there is a relationship between and the operator and for any , the following inequality holds true:

Based on this inequality and known results for the Lusin area integral , the author establishes the strong-type and weak-type estimates for the Littlewood–Paley–Stein function on . In this article, the author also introduces a class of Morrey spaces associated with the Schrödinger operator on . By using some pointwise estimates of the kernels related to the nonnegative potential V, the author establishes the boundedness properties of the operator acting on the Morrey spaces for an appropriate choice of . It can be shown that the same conclusions hold for the operator on generalized Morrey spaces as well.
A Type of Orthonormal Bases on 2-*-Inner Product Spaces
Authors: Najmabadi Behrooz Mohebbi , Shateri Tayebe Lal , Sadeghi Ghadir
Published: December 2020

In this paper, we deﬁne an orthonormal basis for 2-*-inner product space and obtain some useful results. Moreover, we introduce a 2-norm on a dense subset of a 2-*-inner product space. Finally, we obtain a version of the Selberg, Buzano’s and Bessel inequality and its results in an A-2-inner product space.
On ulug oglum agrïp yok bolča in the Bilgä Kagan Inscription
Authors: Yong-Sŏng Li , Kil Park Won
Published: December 2020

This paper attempts to give new explanation for the expression agrïp yok bol- occurring in 9th line of the south side of the Bilgä Kagan Inscription. After a thorough survey of former research and several Chinese sources, the authors came to the conclusion that this expression must be a euphemistic expression for being beheaded in a battle. The authors found also that kog säŋün was Guo Yingjie 郭英傑. In sum, the sentence in question is to be read as ulug oglum agrïp yok bolča kog säŋünüg balbal tikä bertim ‘When my oldest son died of a disease, I readily erected General Kog as a balbal (for him).’ The expression agrïp yok bol- is to be regarded as a euphemistic expression for being beheaded in a battle.
An Ancient East Asian Wanderwort
Authors: Piispanen Peter Sauli
Published: December 2020

The previously non-discussed ancient east Asian Wanderwort araĵaran ‘interjection; barely, suddenly’ is discussed and presented in great detail, and traced throughout many languages phonologically and semantically. The root has also undergone local secondary semantic developments in places, meanings which have then been borrowed into neighboring languages, some already carrying the same root, some borrowing only the new semantic meaning. Aft er detailed lexical documentation of this root in various languages, a possible semantic map is presented at the end of the study. Language groups and languages involved in this very geographically spread out Wanderwort are the Turkic, Tungusic, Mongolic and Yukaghir languages, as well as Tocharian B, Sel’kup, Kamass, Kott, Russian, Japanese and Iñupiatun.
The Buryat Body Parts Names: Face
Authors: Khabtagaeva Bayarma
Published: December 2020

There are six different terms to refer to the ‘face’ in Buryat. The aim of the present paper is to clarify the difference in the usage of all these various terms: which one is used as a body part anatomically, which one is used mostly with metaphorical meanings, which one has a common meaning as appearance, or whether all of them are used equally in all categories. The terms are explored from etymological, semantic and morphological aspects.
Khitan Studies. •
Authors: Yingzhe Wu , Róna-Tas András
Published: December 2020

In the ﬁfth part of this series of papers the authors investigate the way how the Khitan Small Script (KSS) rendered the oral velar and uvular consonants stops in initial position.
A sebészi gerincvelő ischemia és reperfusio hatása a specifikus átáramlásra és a neurológiai következményekre
Authors: Dzsinich Csaba , Gloviczki Péter , Nagy Gabriella , Nagy Klaudia Vivien
Published: December 2020

Összefoglaló. A thoracoabdominalis aorta kirekesztése a gerincvelő
keringésének csökkenését okozza. Az ischemia klinikailag paraparesis, paraplegia
formájában jelenik meg. Ez elsősorban nyitott műtétek során jelent aligha
kiszámítható szövődményt, de a modern endovascularis technikák sem oldották meg
teljes mértékben ennek biztonságos kivédését – bár arányát jelentősen
mérsékelték. A javuló eredmények számos tényezőre vezethetők vissza, mint a
keringés kirekesztési idejének csökkentése, a gerincvelő-funkció és metabolismus
ellenőrzése. Mesterséges keringésjavító direkt és indirekt eljárások, liquor
drainage, hűtés mellett a collateralis keringés javítását szolgáló
prekondicionáló módszerek kerültek bevezetésre. Kísérletes munkánkban 25–30 kg
testsúlyú kutyákon vizsgáltuk – más paraméterek mellett – a distalis perfusio
növelésének, a liquornyomás csökkentésének, illetve ezek kombinációjának
protektív hatását egyórás thoracoabdominalis aortakirekesztés során.
Dolgozatunkban a kísérleti állataink neurológiai végállapotát a keringési
paraméterek és szöveti perfusio és a reperfusio változásainak összefüggésein
keresztül tárgyaljuk. Megállapítottuk, hogy distalis gerincvelő reperfusiós
hyperaemiája szorosan összefügg a neurológiai károsodás mértékével.

Summary. Clamping of the thoracoabdominal aorta reduces perfusion of
the spinal cord significantly, which clinically may present as paraparesis or
paraplegia – devastating and unpredictable complications of open
thoracoabdominal aortic surgery. Introduction of monitoring of evoked potentials
and/or biochemical markers, methods increasing distal arterial pressure,
indirect procedures enhancing residual flow (like liquor drainage), drugs, and
use of hypothermia contributed to achieve better outcome. Preconditioning of
spinal cord circulation is also a promising method. New endovascular techniques
for thoracoabdominal aortic aneurysms and dissections reduced surgical trauma
significantly. Despite all these progressions spinal cord ischemic damage is
still a significant risk. To address this problem we carried out an experimental
work using a canine model focusing on the protective effect of distal arterial
perfusion, spinal fluid drainage, and their combination in a one hour setting of
thoracoabdominal aortic clamping. In this paper we publish our data of
circulatory and specific perfusion parameters of the spinal cord during and
after declamping in correlation of final neurologic outcome.
Thoracoabdominalis aortakirekesztés során fellépő elektrofiziológiai változások a gerincvelőben
Authors: Dzsinich Csaba , Gloviczki Péter , Nagy Gabriella , Nagy Klaudia Vivien
Published: December 2020

Összefoglaló. A thoracoabdominalis aortakirekesztés okozta
gerincvelő ischemia súlyos neurológiai következményeit számos klinikai és
kísérleti tanulmány bizonyítja. E nehezen kiszámítható, súlyos szövődmény
megelőzésének érdekében régi törekvés megfelelő intra- és posztoperatív
monitorizálás kifejlesztése, ami előre jelzi a gerincvelő-funkció romlását,
illetve a kialakuló celluláris károsodást. A legelterjedtebb, a klinikai
gyakorlatban széles körben alkalmazott megoldás a gerincvelői kiváltott motoros
potenciál (MEP) folyamatos ellenőrzése. Ritkábban alkalmazott – bár ígéretes –
eljárás a biokémiai változások nyomon követése, ami a sejtszintű károsodás
markereit használja fel az ischemia okozta változások felismerésére.

Korábbi dolgozatunkban kutyákon végzett kísérleteink azon eredményeit
ismertettük, amelyekben a 60 perces thoracoabdominalis aortakirekesztés okozta
neurológiai változások és a perfúzió adatainak összefüggéseit tárgyaltuk. Jelen
tanulmányunkban a gerincvelői motoros (MEP) és szenzoros (SEP) kiváltott
potenciálok változásait vizsgáljuk a neurológiai végállapot vonatkozásában.
Megállapítottuk, hogy SEP változásai a neurológiai károsodás mértékével
értékelhető összefüggést nem mutatnak. A MEP-amplitúdó és -latencia értékei
biztonsággal jelzik a fenyegető gerincvelő ischemiát. A neurológiai deficit
mélységét (Tarlov 2,1,0) a MEP-értékek változásai numerikusan nem értékelhetően
követik.

Summary. Severe neurological complications of the thoracoabdominal
aortic clamping were published in numerous clinical and experimental studies.
These hardly predictable, devastating consequences demanded to develop a
monitoring system which might detect impending level of spinal cord ischemia in
time – in order to introduce or enhance protective procedures and prevent
permanent neurological deficit. The most widely used monitoring in clinical
practice is the continuous surveillance of the motor evoked potentials (MEP)
during and after thoracoabdominal aortic clamping. Much less used, but promising
opportunity is to control the metabolic changes and cellular integrity utilizing
specific markers like liquor lactate and neuron specific enolase (NSE) etc. In
our earlier study we published data of our canine experiment related to
coherencies between neurological outcome and specific perfusion of the spinal
cord during and after one hour thoracoabdominal aortic clamping. In the present
paper we investigate the behavior of motor evoked (MEP) and sensory evoked (SEP)
potentials related to neurological changes. We conclude the behavior of SEP
values hardly correlate with the neurologic outcome, meanwhile decrease of MEP
amplitude provides reliable signal for developing spinal cord ischemia. We could
not confirm a numeric correlation of these data and the level of the final
neurologic outcome.
Leptin and obesity
Authors: Seth M. , Biswas R. , Ganguly S. , Chakrabarti N. , Chaudhuri A.G.
Published: December 2020

An imbalance between calorie intake and energy expenditure produces obesity. It has been a major problem in societies of the developing and developed world. In obesity an excessive amount of fat accumulates in adipose tissue cells as well as in other vital organs like liver, muscles, and pancreas. The adipocytes containobgenes and express leptin, a 16 kDa protein. In the present communication, we reviewed the molecular basis of the etiopathophysiology of leptin in obesity. Special emphasis has been given to the use of leptin as a drug target for obesity treatment, the role of diet in the modulation of leptin secretion, and reduction of obesity at diminished level of blood leptin induced by physical exercise.
Chiral Separations by Capillary Electrophoresis and related Techniques with Different Chiral Selectors: A Review
Authors: ŞARKAYA Koray , GÖKTÜRK İlgim , YILMAZ Fatma , DENİZLİ Adil
Published: December 2020

Kiral bileşiklerin tanınma mekanizması ve enantiyomerik olarak ayrılması, hem analitik saflık hem de büyük ölçekli çalışmalar için çözüm bulmakla ilgilenen farmakoloji ve doğa bilimlerindeki araştırmacıların büyük ilgisini her zaman uyandıran konulardır. Kapiler Elektroforez, kiral selektörlerin yüksek çözünürlüğü ve yüksek verimliliği gibi üstün özellikleri nedeniyle enantiyomerik ayırımlar için en önemli analitik yaklaşımlardan biri haline gelmiştir. Araştırmacıların ilgi göstermeye devam ettiği bu alanda, teknolojinin ve farklı formdaki kiral selektörlerin gelişim sürecine paralel olarak Kapiler Elektroforez felsefesi temelinde geliştirilen yeni tekniklerin varlığıyla gün geçtikçe gelişmeler ilerlemektedir. Bu derlemede, kapiler elektroforez ve bununla ilişkili teknikler hakkında bazı tanımlayıcı teorik bilgilerin yanı sıra, moleküler baskılanmış polimerler, siklodekstrinler, metal-organik kafesler, iyonik sıvılar, monolitler ve nanopartiküller gibi farklı kiral selektörler kullanılarak kiral ayırmalar üzerine yaklaşık son 10 yıldaki (2010-2020) çalışmalar derlenmiştir.
Erken Dönem Ruhsal Travma, Siber Zorbalık ve Aleksitimi İlişkisi- Relationship Between Early Period Psychic Trauma, Cyber Bullying and Alexithymia
Authors: FEYZİOĞLU Aynur , GÖKTAŞ Seyyide Şifa , SÖĞÜTLÜ Lütfiye
Published: December 2020

ÖZET

Amaç: Çocukluk çağı ruhsal travmaları yetişkinlik dönemi psikopatolojileri için ciddi bir risk etmeni olarak görülmektedir. Siber zorbalık yeni bir çalışma alanı olup ciddiyeti gün geçtikçe artmaktadır. Bu çalışmanın amacı çocukluk çağı ruhsal travmalar siber zorbalık ve aleksitimi arasındaki ilişkiyi incelemektir.

Gereç ve Yöntem: Çalışmaya 20-50 yaş arası 524 genç yetişkin alınmıştır. Katılımcılara internet ortamında Sosyodemografik Veri Formu, Çocukluk Çağı Ruhsal Travmalar Ölçeği (ÇÇRTÖ), Toronto Aleksitimi Ölçeği (TAÖ) ve Yenilenmiş Siber Zorbalık Ölçeği (YSZÖ) uygulanmıştır.

Bulgular: Erken dönem ruhsal travması olan bireylerin siber zorbalığa uğratma ve uğrama puanları ile aleksitimi puanları anlamlı olarak yüksektir. Erken dönem ruhsal travması olan bireylerin siber zorbalığa uğrama puanları uğratma puanlarından anlamlı olarak yüksektir. Siber zorbalığa uğratan ve uğrayan bireylerin aleksitimi puanları anlamlı olarak yüksektir. Aleksitimi, erken dönem ruhsal travmayı ve siber zorbalık aleksitimiyi yordamaktadır.

Sonuç: Çalışmamız psikopatoloji gelişiminde önemli bir faktör olan erken dönem ruhsal travma ile siber zorbalık ve aleksitimi ilişkisini genç yetişkin grupta açıkça göstermektedir.

Anahtar Kelimeler: Çocukluk çağı ruhsal travma, genç yetişkin, siber zorbalık, aleksitimi
Mentira na Perícia Psicológica: Avaliação da Atitude Malinger numa Amostra Forense
Authors: Gonçalves Francisco Valente , Joaquim Rui Mateus , Ferreira Sara , Ângelo Miguel , Ferreira Faria Leonardo
Published: December 2020

Aquando necessário avaliar-se a atitude falsa, como por exemplo a mentira, numa perícia forense, os profissionais que realizam este tipo de trabalho têm limitados os recursos a que podem recorrer. Uma das razões prende-se com o diminuto investimento na investigação na área da avaliação da mentira. Ainda sobre este ponto, avaliar a mentira é uma tarefa extremamente complexa, sendo vários os olhares que um poderá ter para realizar tal ação. Uma possível forma de observar atitudes falsas é a análise da presença de atitudes malinger. No entanto as ferramentas de avaliação a nível psicométrico para esta área são também escassas e pouco elegantes a nível científico. Finalmente, e mais importante, observa-se uma falta de investigação onde as amostras são totalmente forenses. O presente trabalho apresenta uma descrição de uma amostra forense (n = 470) relativamente ao tipo de atitude malinger presente e às características sociodemográficas da mesma. Observam-se alguns pontos de interesse em alguns tipos de características sociais tais como o tipo de habilitação académica ou o tipo de profissão. O tipo de processo jurídico a que os sujeitos em avaliação estão afetos parece ser importante de considerar e finalmente observa-se uma correlação de cerca de 13% em que a inteligência dos sujeitos explica a sua atitude malinger. Mais estudos são necessários. Os dados apresentados neste trabalho são do interesse dos profissionais da especialidade, mas acima de tudo, são acreditados como um passo para se ter uma linha de comparação para investimento científico no futuro na presente área de avaliação forense.
A Mathematical Model of Distributing New Information in Society
Authors: Timofeev Sergey
Published: December 2020

Diversification of any new idea or concept in the society often begins with the emergence in the mass media of information that can win the attention of particular social groups or individuals. The author analyzes and interprets the results obtained by the means of constructing and studying a basic mathematical model of distribution of new information. The article describes factors and regularities that make the basis for the model, comments on all the relators that form the structure of the model, and describes the parameters of this structure. The proposed model is represented by a system of four ordinary differential equations. The stationary points of the system are found, and their conceptual meaning is described. The stationary points have cardinally different properties, depending on different relators. This provides for several possible scenarios of distributing new information in the society, whose description and geometric interpretation is given in the article.
The Concept of an Innovative Model of Combating Organized Crime: Background and Opportunities
Authors: Maksimov Sergey , Vasin Yury
Published: December 2020

An intensive digitization of all social processes (including criminogenic ones) demanded such a degree of rapidity, effectiveness, efficiency and relevance for the decisions taken by modern states that could not be provided using the dominant model of state policy for combating crime. This new civilizational challenge is especially evident for the problem of counteracting organized crime. The authors conclude that the contemporary model of criminal policy against organized crime, whose main idea is a constant strengthening of liability for organized criminal activities, is undergoing a crisis. An indicator of this crisis is a recent amendment of Art. 210 of the Criminal Code of the Russian Federation by a norm that considerably limits criminal prosecution of owners, participants, beneficiaries and managers of judicial persons (or their divisions) for organizing a criminal group or participating in it if the corresponding judicial persons were not originally created with the purpose of committing grave or very grave crimes. The same norm limits criminal prosecution of the above-mentioned categories of physical persons if the latter did not possess direct knowledge of the criminal purposes for which such judicial persons were created. The authors believe that the crisis of the current model of combating organized crime is also proven by a lack of any significant correlation between the changes in the criminal legislation on liability for organized criminal activities during the last 24 years and changes in the intensity of the practice of its enforcement. This conclusion, according to the authors, makes it possible to infer that goals that the lawmakers set while trying to improve the effectiveness of combating organized crime were probably not achieved. The authors claim that the key causes of the unproductive reaction of lawmakers and law enforcers to the growing activities of organized crime, including its influence on the general state of law and order and the economic security of the state, include a selective post factum reaction to the growth of specific manifestations of organized crimes based on the intuitive trial and error approach. The authors suggest using the following ideas for the concept of an innovative model of influencing organized crime: it is necessary to use mathematical modeling of the planned amendments to criminal or other connected legislation and their influence both on the system of legal norms of the amended act and the system of legal norms as a whole, on the practice of law enforcement and criminal activity; the state should react to all the specific reasons for the initiation of criminal cases on organized criminal activities using automated systems of collecting, processing and evaluating information, making predictions of the changes in the intensity of organized criminal behavior; the causes and conditions of specific organized criminal infringements should be revealed and measures should be taken to eliminate them.
Illicit Enrichment: a New Approach to Criminalizing the Act
Authors: Golovin Alexander , Bugayevskaya Natalia
Published: December 2020

The authors analyze the necessity and expediency of incorporating the norm on liability for illicit enrichment into Russian criminal legislation in accordance with the requirements of Art. 20 of the United Nations Convention against Corruption of 2003. The ratification of this international legal document placed Russian lawmakers under an obligation to modernize the anti-corruption legislation, including an obligation to recognize the illegal character of the actions of those officials whose assets have increased disproportionally to their legal income. The authors recognize the existence of different approaches to estimating illicit enrichment as corpus delicti. They rebut the allegation that establishing criminal liability for illicit enrichment does not correspond to the principles of criminal and criminal procedure law; they draw parallels with the current corpora delicti (illegal entrepreneurship and others) in criminal law and prove that establishing that a person possesses certain assets does not contradict the principle of guilt and the principle of the presumption of innocence. The criminal law analysis of illicit enrichment was carried out using the method of modeling corpus delicti with the use of constructions suggested by other scholars and the authors of the draft law on changes in the Criminal Code of the Russian Federation regarding this corpus delicti. The criticism of the suggested models and the research of some elements of corpus delicti, specifically, the objective side of illicit enrichment, led the authors to the conclusion that it is impossible to include this corpus delicti into law because it does not correspond to the requirements of the constitutional and criminal law principle of justice. The impossibility of criminalizing illicit enrichment does not contradict the recommendatory character of conventional norms and does not result in a gap in law. The problem is solved on the basis of legislation on public service, civil and civil procedure legislation. The examined court practice regarding the cases in which the prosecutors requested to turn into a state income the assets whose licit acquisition has not been proven makes it possible to claim that international anti-corruption standards connected with illicit enrichment have been put into practice.