bluuebunny/crossref_metadata_2025 huggingface dataset:
Gaussian Process Modeling Blazar Multiwavelength Variability: Indirectly Resolving Jet Structure
Authors: Zhang 张 Haiyun 海云 , Yan 闫 Dahai 大海 , Zhang 张 Li 力
Published: February 2023

Blazar jet structure can be indirectly resolved by analyzing the multiwavelength variability. In this work, we analyze the long-term variability of blazars in radio, optical, and X-ray energies with the Gaussian process (GP) method. The multiwavelength variability can be successfully characterized by the damped-random walk model. The nonthermal optical characteristic timescales of 38 blazars are statistically consistent with the γ-ray characteristic timescales of 22 blazars. For three individual sources (3C 273, PKS 1510-089, and BL Lac), the nonthermal optical, X-ray, and γ-ray characteristic timescales are also consistent within the measured 95% errors, but the radio timescale of 3C 273 is too large to be constrained by the decade-long light curve. The synchrotron and inverse-Compton emissions have the same power spectral density, suggesting that the long-term jet variability is irrelevant to the emission mechanism. In the plot of the rest-frame timescale versus black hole mass, the optical-γ-ray timescales of the jet variability occupy almost the same space with the timescales of accretion disk emission from normal quasars, which may imply that the long-term variabilities of the jet and accretion disk are driven by the same physical process. It is suggested that the nonthermal optical-X-ray and γ-ray emissions are produced in the same region, while the radio core, which can be resolved by very long baseline interferometry, locates at a far more distant region from the black hole. Our study suggests a new methodology for comparing thermal and nonthermal emissions, which is achieved by using the standard GP method.
Inflationary and Phase-transitional Primordial Magnetic Fields in Galaxy Clusters
Authors: Mtchedlidze Salome , Domínguez-Fernández Paola , Du Xiaolong , Schmidt Wolfram , Brandenburg Axel , Niemeyer Jens , Kahniashvili Tina
Published: February 2023

Primordial magnetic fields (PMFs) are possible candidates for explaining the observed magnetic fields in galaxy clusters. Two competing scenarios of primordial magnetogenesis have been discussed in the literature: inflationary and phase-transitional. We study the amplification of both large- and small-scale correlated magnetic fields, corresponding to inflation- and phase transition–generated PMFs, in a massive galaxy cluster. We employ high-resolution magnetohydrodynamic cosmological zoom-in simulations to resolve the turbulent motions in the intracluster medium. We find that the turbulent amplification is more efficient for the large-scale inflationary models, while the phase transition–generated seed fields show moderate growth. The differences between the models are imprinted on the spectral characteristics of the field (such as the amplitude and the shape of the magnetic power spectrum) and therefore also on the final correlation length. We find a one order of magnitude difference between the final strengths of the inflation- and phase transition–generated magnetic fields, and a factor of 1.5 difference between their final coherence scales. Thus, the final configuration of the magnetic field retains information about the PMF generation scenarios. Our findings have implications for future extragalactic Faraday rotation surveys with the possibility of distinguishing between different magnetogenesis scenarios.
Observations of Waves and Structures by Frequency–Wavenumber Spectrum in Solar Wind Turbulence
Authors: Zhao L.-L. , Zank G. P. , Nakanotani M. , Adhikari L.
Published: February 2023

A well-known shortcoming of single-spacecraft spectral analysis is that only the 1D wavenumber spectrum can be observed, assuming the characteristic wave propagation speed is much smaller than the solar wind flow speed. This limitation has motivated an extended debate about whether fluctuations observed in the solar wind are waves or structures. Multispacecraft analysis techniques can be used to calculate the wavevector independent of the observed frequency, thus allowing one to study the frequency–wavenumber spectrum of turbulence directly. The dispersion relation for waves can be identified, which distinguishes them from nonpropagating structures. We use magnetic field data from the four Magnetospheric Multiscale (MMS) spacecraft to measure the frequency–wavenumber spectrum of solar wind turbulence based on the k-filtering and phase differencing techniques. Both techniques have been used successfully in the past for the Earth’s magnetosphere, although applications to solar wind turbulence have been limited. We conclude that the solar wind turbulence intervals observed by MMS show features of nonpropagating structures that are associated with frequencies close to zero in the plasma rest frame. However, there is no clear evidence of propagating Alfvén waves that have a nonzero rest-frame frequency. The lack of waves may be due to instrument noise and spacecraft separation. Our results support the idea of turbulence dominated by quasi-2D structures.
The Gas and Stellar Content of a Metal-poor Galaxy at z = 8.496 as Revealed by JWST and ALMA
Authors: Heintz K. E. , Giménez-Arteaga C. , Fujimoto S. , Brammer G. , Espada D. , Gillman S. , González-López J. , Greve T. R. , Harikane Y. , Hatsukade B. , Knudsen K. K. , Koekemoer A. M. , Kohno K. , Kokorev V. , Lee M. M. , Magdis G. E. , Nelson E. J. , Rizzo F. , Sanders R. L. , Schaerer D. , Shapley A. E. , Strait V. B. , Toft S. , Valentino F. , Wel A. van der , Vijayan A. P. , Watson D. , Bauer F. E. , Christiansen C. R. , Wilson S. N.
Published: February 2023

We present a joint analysis of the galaxy S04590 at z = 8.496 based on NIRSpec, NIRCam, and NIRISS observations obtained as part of the Early Release Observations program of the James Webb Space Telescope (JWST) and the far-infrared [C ii] 158 μm emission line detected by dedicated Atacama Large Millimeter/submillimeter Array (ALMA) observations. We determine the physical properties of S04590 from modeling of the spectral energy distribution (SED) and through the redshifted optical nebular emission lines detected with JWST/NIRSpec. The best-fit SED model reveals a low-mass (M
⋆ = 107.2–108
M
⊙) galaxy with a low oxygen abundance of

12
+
log
(
O

/

H
)
=

7.16

−
0.12

+
0.10

derived from the strong nebular and auroral emission lines. Assuming that [C ii] effectively traces the interstellar medium, we estimate the total gas mass of the galaxy to be M
gas = (8.0 ± 4.0) × 108
M
⊙ based on the luminosity and spatial extent of [C ii]. This yields an exceptionally high gas fraction, f
gas = M
gas/(M
gas + M
⋆) ≳ 90%, though one still consistent with the range expected for low metallicity. We further derive the metal mass of the galaxy based on the gas mass and gas-phase metallicity, which we find to be consistent with the expected metal production from Type II supernovae. Finally, we make the first constraints on the dust-to-gas (DTG) and dust-to-metal (DTM) ratios of galaxies in the epoch of reionization at z ≳ 6, showing overall low mass ratios of logDTG < −3.8 and logDTM < −0.5, though they are consistent with established scaling relations and in particular with those of the local metal-poor galaxy I Zwicky 18. Our analysis highlights the synergy between ALMA and JWST in characterizing the gas, metal, and stellar content of the first generation of galaxies.
Assessment of risk factors associated with outbreak of hepatitis A in Shakrial, Rawalpindi, Pakistan
Authors: Badar Aamir , Malik Muhammad Wasif , Hasnain Syed Zain , Shah Syed Ijaz Ali , Shabbir Rana Muhammad Kamran , Haider Waseem , Ahmed Haroon
Published: February 2023

Introduction: Two patients with jaundice reported to the National Institute of Health (NIH), Islamabad from Shakrial, Rawalpindi in April 2017. An outbreak investigation team was formulated to assess the disease magnitude, risk factors and control measures.
Methodology: A case-control study was conducted in 360 houses in May 2017. The case definition was: onset of acute jaundice with any symptom including fever, right upper-quadrant pain, loss of appetite, dark urine, nausea and vomiting among Shakrial residents from March 10 - May 19, 2017. Four age and gender matched controls were selected for each case. Blood samples were sent to the NIH for laboratory confirmation. Frequencies, attack rates (AR), odd ratios, and logistic regression were computed at 95% confidence interval and p < 0.05.
Results: A total of 25 cases (23 new) were identified with mean age 8 years and male to female ratio 1.5:1. Overall AR was 1.39% and the most severely affected age-group was 5-10 years (AR of 3.92%). Multivariate analysis revealed that raw vegetable consumption, lack of awareness and poor handwashing practices had significant association with disease spread. All blood samples were positive for hepatitis A, and no resident was previously vaccinated. Lack of awareness of disease spread among the community was the most probable reason for the outbreak. There were no new cases during follow up until May 30, 2017.
Conclusions: Healthcare departments should implement public policies towards the management of hepatitis A in Pakistan. Health awareness sessions and vaccination for children ≤ 16 years age is recommended.
Respiratory perspective of COVID-19 in pregnancy
Authors: Purwono Arini , Agustin Heidy , Lisnawati Yuyun , Faisal Hana Khairina Putri
Published: February 2023

The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was declared a global pandemic in March 2020 by the World Health Organization (WHO). By February 2022, the disease had infected more than 500 million people globally. COVID-19 frequently manifests as pneumonia and mortality is mainly caused by acute respiratory distress syndrome (ARDS). Previous studies have reported that pregnant women are at a higher risk of SARS-CoV-2 infection and complications can happen due to alterations in the immune response, respiratory physiology, hypercoagulable state, and placental pathology. Clinicians face the challenge of selecting the proper treatment for pregnant patients with different physiological characteristics compared with the non-pregnant population. Furthermore, drug safety for both the patient and the fetus should also be considered. Efforts to prevent COVID-19, including prioritizing vaccination for pregnant women, are essential to break the chain of COVID-19 transmission in the pregnant population. This review aims to summarize the current literature regarding the effect of COVID-19 in pregnant women, its clinical manifestations, treatment, complications, and prevention.
Antimicrobial profile of non-typhoidal Salmonella isolated from raw sewage in the Metropolitan Region of São Paulo, Brazil
Authors: Martone-Rocha Solange , Dropa Milena , Moreira Calixto da Cruz Beatriz , Belisário Mendes Oliveira Leite Débora , Pereira dos Santos Talita , Pepe Razzolini Maria Tereza
Published: February 2023

Introduction: Non-typhoidal Salmonella (NTS), are frequently found in sewage and are one of the main causes of diarrhea in developed and developing countries due to poor sanitation conditions. In addition, NTS can potentially act as reservoirs and vehicles for the transmission of antimicrobial resistance (AMR), which can be facilitated by the discharge of sewage effluents into environmental matrices. This study aimed to analyze a NTS Brazilian collection, focusing on their antimicrobial susceptibility profile and the presence of clinically relevant AMR-encoding genes.
Methodology: Forty-five non-clonal NTS strains from serotypes Salmonella enteritidis (n = 6), Salmonella enterica serovar 1,4,[5],12:i:- (S. 1,4,[5],12:i:-) (n = 25), Salmonella cerro (n = 7), Salmonella typhimurium (n = 3) and Salmonella braenderup (n = 4) were studied. Antimicrobial susceptibility testing was done using the Clinical and Laboratory Standards Institute guidelines (2017) and genes encoding resistance to beta-lactams, fluoroquinolones and aminoglycosides were identified by polymerase chain reaction and sequencing.
Results: Resistance to β-lactams, fluoroquinolones, tetracyclines and aminoglycosides was frequent. The highest rates were observed for nalidixic acid (89.0%), followed by tetracycline (67.0%), ampicillin (67.0%), amoxicillin + clavulanic acid (64.0%); ciprofloxacin (47.0%) and streptomycin (42.0%). The AMR-encoding genes detected were qnrB, oqxAB, blaCTX-M and rmtA.
Conclusions: Raw sewage has been considered a valuable tool to evaluate epidemiological population patterns and this study supports the view that NTS with pathogenic potential and resistance to antimicrobials are circulating in the studied region. This is worrisome due to the dissemination of these microorganisms throughout the environment.
Clinical pharmacist-initiated assessment and amelioration of appropriate antibiotic use in surgical units at a South Indian tertiary care hospital - A handshake approach
Authors: Kuruvilla Ann Vazhayil , Madhan Ramesh , Chandagal Puttaswamy Madhu
Published: February 2023

Introduction: Studies on the appropriateness of antibiotic use among surgical patients are limited in developing countries, notably in India. Therefore, we aimed to evaluate the inappropriateness of antibiotic use, demonstrate the impact of clinical pharmacist interventions and determine the predictors of inappropriate use of antibiotics in the surgical units of a South Indian tertiary care hospital.
Methods: This was a 1-year prospective interventional study on in-patients of the surgical wards to determine the appropriateness of the prescribed antibiotics by reviewing medical records using available antimicrobial susceptibility test reports and medical evidence. When inappropriateness in antibiotic prescriptions was identified, the clinical pharmacist discussed and conveyed apt suggestions to the Surgeon. Bivariate logistic regression analysis was applied to evaluate its predictors.
Results: Among the 660 antibiotic prescriptions of 614 patients that were followed and reviewed, about 64% were inappropriate. Most inappropriate prescriptions were witnessed in the cases that involved the gastrointestinal system (28.03%). Among the inappropriate cases, 35.29% were attributed to an excessive regimen of antibiotic use which marked the highest. Based on the category of use, most of the antibiotics were used inappropriately as prophylaxis (76.7%) followed by empirical (71.31%). The increase in the percentage of the appropriate use of antibiotics resulting from pharmacist intervention was 95.06%. There was a significant link between inappropriate antibiotic use and the presence of two or three comorbid conditions, the use of two antibiotics, and length of hospital stay of 6-10 days and 16-20 days (p < 0.05).
Conclusions: An antibiotic stewardship program in which the Clinical pharmacist is an integral part along with well-framed institutional antibiotic guidelines must be implemented to assure appropriate antibiotic use.
Albanian university students' knowledge, attitudes, and practices regarding COVID-19 infection and vaccine: A cross-sectional study
Authors: Merkuri Lumturi , Puca Edmond , Kamberi Fatjona , Alimehmeti Ilir , Qorri Erda , Borshi Xhejni
Published: February 2023

Introduction: COVID-19 pandemic remains a public health concern worldwide. Given that, students represent a subgroup of the population with an impact on the pandemic.
Aim: The aim of this study is to evaluate the knowledge, attitudes, and practices of Albanian students about COVID-19, and to provide a database to plan and implement preventive evidence-based interventions.
Methodology: An online survey was conducted among Albanian university students during April-May 2022, to collect information on their knowledge, attitudes, and practices related to COVID-19, through a structured questionnaire.
Results: A total of 906 students, 72.8% females, were included in it. 93.4% of participants knew the ways of transmission of COVID-19; 92.5% had information about preventive measures, but only 30% knew about quarantine and 37.0% knew vaccination as a preventive measure. Regarding attitudes, 54.8% of participants believed that COVID-19 infection is very dangerous. 46.5% have a negative attitude toward covid vaccines. Almost all respondents (93.7%) apply regular hand washing as a preventive measure; 82.8% cover their mouth when coughing or sneezing; but only 28.2% always use a mask indoors.
Conclusions: Albanian university students had good knowledge, positive attitudes, and appropriate preventive practices against COVID-19, but the study found that some limitations in terms of information and misconceptions still exist. Raising awareness and providing adequate information, education, and more effective communication programs will have a positive impact on increasing knowledge, improving attitudes, and supporting the required student behavior change.
The Effect of Pregabalin Levels on Pain and Substance P Level Post-Cesarean Section
Authors: Gaus Syafruddin , Harahap Muhammad Wirawan , Ahmad Muhammad Ramli , Husain Alamsyah Ambo Ala , Wirawan Nur Surya
Published: February 2023

BACKGROUND: Post-operative pain is a very important problem faced by post-operative patients. Antihyperalgesia is caused by the inhibition of the neurotransmitter glutamate and substance P (SP) by pregabalin. This study aimed to compare the effect of preventive administration of 50 mg oral pregabalin and 1 g paracetamol with 75 mg oral pregabalin and 1 g intravenous paracetamol on Numeric Rating Scale (NRS) scores and SP levels after cesarean section with spinal anesthesia.
AIM: The objective of the study was to compare the effect of preventive administration of 50 mg oral pregabalin and 1 g paracetamol with 75 mg oral pregabalin and 1 g intravenous paracetamol on NRS scores and SP levels after cesarean section with spinal anesthesia.
METHODS: This study used a double-blind randomized trial design. Samples were selected randomly and consecutively from the entire population that met the inclusion criteria. There were a total of 30 samples. SP levels were measured 2 h before cesarean section. The study drug was administered by mouth with a sip of water 1 h before the expected time of the surgical incision. SP levels were checked at the 4th h (SP 1) and 6th h (SP 2) postoperatively. The assessment of the degree of pain using the NRS was carried out at 2 h, 4 h, 6 h, 12 h, and 24 h postoperatively. This study used the Mann–Whitney U-test to compare both the levels of SP and NRS between the two groups.
RESULTS: The results of this study showed that there was a significant difference in the NRS scores between the 50 mg and 75 mg pregabalin groups (p < 0.05). In the 75 mg pregabalin group, the NRS scores were lower than in the 50 mg pregabalin group in patients undergoing CS surgery under spinal anesthesia. There was a significant difference in SP levels between the 50 mg and 75 mg pregabalin groups (p < 0.05). SP levels in the 50 mg pregabalin group increased at 4 h and 6 h postoperatively, while in the 75 mg pregabalin group, it tended to decrease at 4 h and 6 h postoperatively.
CONCLUSION: The quiescent and mobile NRS scores in the 75 mg pregabalin group were lower than the 50 mg pregabalin group with a combination of 1 g intravenous paracetamol after SC surgery. SP levels in the 75 mg pregabalin group decreased compared to the 50 mg pregabalin group with a 1 g intravenous paracetamol combination which experienced an increase after CS surgery. Pregabalin 75 mg is recommended for preventive use in CS surgery.
Intravenous Granisetron Combined with Dexamethasone in Cesarean Section Patients Undergoing Spinal Anesthesia
Authors: Gaus Syafruddin , Sjattar Irfan Faisal , Salahuddin Andi , Ahmad Muhammad Ramli , Wirawan Nur Surya , Seweng Arifin
Published: February 2023

BACKGROUND: Regional anesthesia, including spinal anesthesia, is the technique-of-choice over general anesthesia for cesarean section (C-section). Nausea, vomiting, and shivering are common after spinal anesthesia. Granisetron and dexamethasone are used as a premedication to prevent these reactions. AIM: This study determined the effect of different doses of granisetron combined with dexamethasone for the prevention of nausea, vomiting, and shivering. PATIENTS AND METHODS: This double-blind randomized clinical trial included patients undergoing C-section under spinal anesthesia at several hospitals in Makassar, Indonesia. Forty-five cases were divided into three equal-sized groups: G5, administered intravenous (IV) granisetron at 5 mcg/kg body weight (BW); G10, administered IV granisetron at 10 mcg/kgBW; and G25, administered IV granisetron at 25 mcg/kgBW. All patients also received IV dexamethasone at 0.1 mg/kgBW. RESULTS: In the G10 group, three cases experienced mild nausea, while, in the G5 and G25 groups, there were no incidences of nausea; this was a statistically significant difference (p = 0.043). Vomiting was not reported in any group. The G25 group had the lowest number of patients experiencing shivering (one case with a score of 3), but there were no significant differences in shivering incidence between groups (p = 0.164). CONCLUSION: Granisetron is effective in reducing nausea and shivering at certain dosage.
Baiyuerius, a new genus of Coelotinae (Araneae, Agelenidae) spiders from China and Vietnam
Authors: Li Bing , Zhao Zhe , Zhang Xiaoqing , Ballarin Francesco , Li Shuqiang
Published: February 2023

Baiyuerius Li, Zhao & Li gen. n., a new genus of the subfamily Coelotinae F. O. Pickard-Cambridge, 1893 is described, including five new species: B. daxi Li, Zhao & Li sp. n. (♀), B. pindong Li, Zhao & Li sp. n. (♂), B. tamdao Li, Zhao & Li sp. n. (♀), B. zhuping Li, Zhao & Li sp. n. (♂), and B. zuojiang Li, Zhao & Li sp. n. (♂♀), from southern China and the north of Vietnam. Our molecular analysis supports Baiyuerius Li, Zhao & Li gen. n. as monophyletic and as a sister group of the newly established genus Yunguirius.
Nuclear Weapons and Extinction As Progress
Authors: Gardiner Michael
Published: February 2023

Nuclear weapons have delivered more near-extinction encounters than any other anthropogenic threat, but for the three decades after the Cold War discussion of this threat was relatively sidelined. This paper points to some of the historical connections between 'war-ending' weapons,
deterrence logic and its breakdown, and the binding between the sublimation of politics into commerce and an extinction logic held within it. It firstly gestures towards roots in the ideal of market mediation as civilisation rising in the eighteenth century; secondly it looks at some writing
on the conception of nuclear weapons and the surprisingly long history of awareness of anthropogenic extinction risk this brings; thirdly it suggests that a post-Cold War revival of the binding of market realism to progress that had led to the 'weapon to end war', and the condition of deterrence,
helps explain the fall in discussions of nuclear extinction; and fourthly it notes that current proliferation and destabilisation question this deep and largely unspoken conventional wisdom over nuclear 'non-violence'. It points to various moments in the imagination and realisation of viable
nuclear weapons and their embedding in democratic regimes in Atlantic powers in particular, and to points of serious scientific consideration of extinction during the Cold War, and suggests that the long naturalisation of nuclear weapons has taught us to 'live extinction' in a way that speaks
to other anthropogenic risks. Climate and nuclear crises indeed can be read as nodes on a trajectory of extraction and exchange defining a narrow conception of progress that has extinction as its telos. Ideas of 'total' deterrence become widespread during the imperial rivalries following
this extractive-productive ethics, and take nuclear form as early as the first decades of the twentieth century. After 'stable' deterrence, though, as nuclear arsenals remained to back the Anglo-American 'victory' in the Cold War, these arsenals reached the apotheosis of their long depoliticising,
dehumanising mission, standing as a silent horizon absorbing conflict and helping to explain a lack of political 'newness' often felt during late neoliberalism. With the more recent complex and largely obscured re-arming, nuclear weapons are being rediscovered as both an existential threat
and an imperative to rethink the scope of political action.
The Popular Culture of Extinction and The Racialisation of Survival
Authors: Pitcher Ben
Published: February 2023

Framed by an understanding of the distant human past, this article considers how species extinction has become a prominent resource in the cultural present. The environmental activism of Extinction Rebellion and the nonfiction bestseller Sapiens provide examples of where the
theme of human survival and extinction is currently playing out in contemporary Western culture. This article goes on to give a more detailed reading of TV survival shows as sites of popular cultural meditation on Homo sapiens's vulnerability as a species. Survival shows explore the
terms of our own survival, reflecting on the possibility of starting again and providing scenarios that consider how to live without the technologies and infrastructure on which we have come to rely.
 Placing particular emphasis on the interwoven and mutually defining discourses
of race and species identity, I attend to the racialisation of survival. In TV survival shows I suggest that the vulnerability of the human species comes to be animated through a kind of existential blackface: the inhabitation of environments, the simulation of experiences and the mimicry
of social and cultural forms imputed to nonspecific Indigenous others. As Western culture imagines the terms of its own survival, racial and Indigenous others serve to model alternative visions of humanity pushed forwards and backwards in time, representing a forgotten but intrinsic premodern
and prehistoric core, or the antecedents of a post-apocalyptic future.
The Way Home: Space Migration And Disorientation
Authors: Shaw Debra Benita
Published: February 2023

At a time when the viability of planet Earth as a suitable home for the human species is in doubt, outer space is big business. This paper examines the politics of space migration and its effects in perpetuating myths of human exceptionalism. How can we think differently about the ontological
determinants that govern our relationship to the planet that we think of as home?
Beginning Again at the End: A Dialectics of Extinction
Authors: Ware Ben
Published: February 2023

This essay makes three connected moves. First, it examines various modalities of 'the end' in philosophy and contemporary neoliberal culture, asking what new political lessons might be drawn from each. Second, it looks at different dialectical ideas of catastrophe: Günther Anders'
and JeanPierre Dupuy's notion of 'enlightened doomsaying'; and Maurice Blanchot's and Theodor Adorno's contention that only in the face of extinction does humanity become visible in the first place. Third, the essay concludes by proposing a move beyond Blanchot and Adorno. We don't just need
to look the negative (extinction) in the face, but to move into the zone of politics proper: to recognise that only the negation of this world – a world of converging and multiplying catastrophes – ends the prospect of the end of the world – understood not as
a sudden death, but rather as an incremental decay, the slow unravelling of intimately entangled forms of life.
Endométriose et qualité de vie : le rôle du soutien social et des stratégies de coping
Authors: Guillemot Cassandra , Garraud Clotilde , Sordes Florence
Published: February 2023

L’endométriose est une maladie gynécologique évolutive et chronique, caractérisée par la présence de tissu endométrial hors de la cavité utérine, pouvant coloniser et se développer sur les organes avoisinants. La maladie engendre de véritables remaniements psychologiques, nous incitant à interroger l’influence du soutien social et des stratégies de coping sur le niveau de qualité de vie des patientes. Un échantillon de 550 femmes de 18 à 54 ans diagnostiquées ont répondu à des questionnaires évaluant le soutien social (SSQ-6), les stratégies d’ajustements (WCC-R) leur niveau de qualité de vie (MOS SF-36), les données sociodémographiques et biomédicales. Nos analyses montrent que le soutien social et les stratégies de coping centrées sur le problème sont corrélés positivement avec le niveau de qualité de vie. Les analyses de régression montrent également que ces variables sont des déterminants d’une qualité de vie optimale. Ces résultats appuient l’idée que l’évaluation subjective du soutien social perçu ainsi que certaines stratégies d’ajustement ont des répercussions sur le niveau de qualité de vie des femmes atteintes d’endométriose.
Des citoyennes délibératives et des citoyens délibératifs : la Convention citoyenne pour le climat face à la délibération
Authors: Apouey Bénédicte , Fourniau Jean-Michel , Tournus Solène
Published: February 2023

Le processus de recrutement (le « tirage au sort ») d’un mini-public conduit à sélectionner des volontaires motivé·es et disponibles pour participer à l’assemblée. Cependant, leurs dispositions pour la délibération ne se révèlent qu’en situation et dépendent largement du déroulement même du processus délibératif. L’analyse des réponses des volontaires participant à la Convention citoyenne pour le climat à des questionnaires portant sur la qualité délibérative des échanges, ainsi que leur comparaison avec celles données par les participant·es aux conférences citoyennes régionales du Grand débat national (France, 2019) et du G1000 (Belgique, 2011), permettent de saisir l’expression de dispositions relationnelles dans les interactions qui font d’une situation délibérative une expérience partagée. Nous employons l’expression « citoyennes délibératives et citoyens délibératifs » pour qualifier les interactions entre dispositions individuelles et dispositif délibératif, constitutives de l’expérience partagée. L’écoute et le respect entre participant·es, la sincérité des prises de parole et leur orientation vers le bien commun, le goût pour l’expression du désaccord politique en face à face forment la confiance des citoyennes délibératives et des citoyens délibératifs dans leur capacité collective à produire des propositions efficaces et justes. Un programme comparatif international permettrait de documenter leur expérience en saisissant plus finement les dispositions individuelles favorables à la délibération, leur formation et leur dynamique, en interrogeant les comportements qui les manifestent selon les motifs de participation.
Microbiological and chemical safety ofBombyx mori farmed in north-eastern Italy as a novel food source
Authors: Marzoli F. , Tata A. , Massaro A. , Bragolusi M. , Passabì E. , Cappellozza S. , Saviane A. , Tassoni L. , Piro R. , Belluco S.
Published: February 2023

Sericulture in Italy has old origins, but competitiveness with the Asian markets and the widespread use of pesticides have led, in the past, to a decline ofBombyx mori (BM) farming. However, this sector is characterised by future development potential due to the use of all BM products in the food sector, which would promote a sustainable production chain. The aim of the present study was to determine the nutritional composition and the presence of chemical and microbiological hazards in BM. Based on the microbiological criteria reported by the Regulation (EU) 2017/2470 and amendments for already authorised edible insect species, the samples of chrysalides met the criteria set forEscherichia coli, Listeria monocytogenes, Salmonella spp., Bacillus cereus, Coagulase positive Staphylococci, and sulphite-reducing anaerobes. Some samples were not compliant with the criteria set for total aerobic colony count,Enterobacteriaceae, yeasts and moulds. B. cereus was detected only in cocoon samples. Traces of fungicides, polycyclic aromatic hydrocarbons, dioxins-PCBs and heavy metals (Pb and As) were observed in chrysalides, chrysalis oil and defatted chrysalis meal. Cd and Hg were not detected in any sample. Traces of mycotoxins were detected only in chrysalis oil and defatted chrysalis meal, not in chrysalides. The content of lipids and proteins in chrysalides ranged between 34.42-39.19% and 38.13-50.17%, respectively. In addition, no difference was observed in element content (P, S, Cl, K, Ca, Mn, Fe, Cu, Zn) between chrysalides and chrysalis meal. The present study highlights the possible impact of contamination of the rearing and processing environments on the microbial and chemical safety of BM and derivative products.
Repetitive Transcranial Magnetic Stimulation in Bipolar Depression: Current Evidence and Future Perspectives
Authors: Barksdale Bryan R. , Fonzo Gregory A.
Published: February 2023

Depressive episodes are more common and last longer in patients with bipolar disorder relative to manic or hypomanic episodes. They are often refractory to current pharmacologic treatment strategies, resulting in increased morbidity and mortality. There has been increased interest in neuromodulatory treatments, namely repetitive transcranial magnetic stimulation (rTMS) for treating bipolar depression, given its proven efficacy in unipolar depression. This review seeks to summarize the current evidence regarding the efficacy of rTMS for the treatment of depression in bipolar disorder, identify limitations, and provide suggestions for future research on the use of rTMS in the treatment of bipolar depression.

[
Psychiatr Ann
. 2023;53(2):68–72.]
On submodule transitivity of QTAG-modules
Authors: Sikander Fahad , Begam Firdhousi , Fatima Tanveer
Published: February 2023

In this paper, we generalize a suitable transformation from an element-based to a submodule-based interpretation of the traditional idea of transitivity in QTAG modules. We examine QTAG modules that are transitive in the sense that the module has an automorphism that sends one isotype submodule $ K $ onto any other isotype submodule $ K' $, unless this is impossible because either the submodules or the quotient modules are not isomorphic. Additionally, the classes of strongly transitive and strongly $ U $-transitive QTAG modules are defined using a slight adaptations of this. This work investigates the latter class in depth, demonstrating that every $ \alpha $- module is strongly transitive with regard to countably generated isotype submodules.
Synchronization and fluctuation of a stochastic coupled systems with additive noise
Authors: Liu Biao , Zhao Meiling
Published: February 2023

The synchronization and fluctuation of a stochastic coupled system with additive noise were investigated in this paper. According to the relationship between the stochastic coupled system and multi-scale system, an averaging principle in which the multi-scale system with singular coefficients was established, thereby the synchronization of stochastic coupled systems was obtained. Then the convergence rate of synchronization was also obtained. In addition, to prove fluctuation of multi-scale system, the martingale approach method was used. And then the fluctuation of the stochastic coupled systems was got. In the end, we give an example to illustrate the utility of our results.
Improved collaborative filtering personalized recommendation algorithm based on k-means clustering and weighted similarity on the reduced item space
Authors: Huang Jiaquan , Jia Zhen , Zuo Peng
Published: February 2023

Collaborative filtering (CF) algorithm is one of the most widely used recommendation algorithms in recommender systems. However, there is a data sparsity problem in the traditional CF algorithm, which may reduce the recommended efficiency of recommender systems. This paper proposes an improved collaborative filtering personalized recommendation (ICF) algorithm, which can effectively improve the data sparsity problem by reducing item space. By using the k-means clustering method to secondarily extract the similarity information, ICF algorithm can obtain the similarity information of users more accurately, thus improving the accuracy of recommender systems. The experiments using MovieLens and Netflix data set show that the ICF algorithm has a significant improvement in the accuracy and quality of recommendation.
Social Robotics in Education: A Survey on Recent Studies and Applications
Authors: Youssef Karim , Said Sherif , Alkork Samer , Beyrouthy Taha
Published: February 2023

Over the last years, social robots have been conceived to be used in various domains and for different purposes. This paper presents a survey on different applications and aspects of social robots in education. Different contexts are seen, ranging from children education, until higher education. A variety of applications and studies are reported, in areas like as second language tutoring, teaching assistance, and storytelling. Robotic platforms used in these applications are observed, and means of evaluation of users perception of robots are presented.
Running an Online Mathematics Examination with STACK
Authors: Sangwin Christopher
Published: February 2023

In this paper I discuss running an online examination with STACK for a year 1 "Introduction to Linear Algebra" course. The COVID pandemic has continued to disrupt teaching during 2021-22, and were are still not able to return to the examination hall for a traditional exam. Instead, our examinations were still "take home". Under these circumstances we wrote a fully automatically marked final test for the course. With over 800 students on the course in 2021-22, the paper-based examination was estimated to cost about 50 person-days to mark. Clearly, reducing this cost is an attractive prospect. However, important questions remain. To what extent can we write questions which cover the learning objectives of the course? How did the students do with the test? What recommendations can we offer for similar courses, and future years? In particular, do we need to return to the exam hall?
AuthOMath: Combining the Strengths of STACK and GeoGebra for School and Academic Mathematics
Authors: Pinkernell Guido , Diego-Mantecón Jose Manuel , Lavicza Zsolt , Sangwin Christopher
Published: February 2023

GeoGebra has its strength in creating multimodal dynamic and interactive math applets and is widely used in secondary school math teaching. STACK is particularly strong in generating randomized task with adaptive feedback and is mostly used in academic math teaching. The Erasmus+ project AuthOMath (2022 – 2024) aims to combine the strengths of both systems in an authoring tool with a transformative digitization potential in mathematics teaching and learning.
Essential fatty acids in farmed tambaqui (Colossoma macropomum) from the Brazilian Amazon Area
Authors: Santos Tatiana Soares dos , Souza Ernané dos Santos , Bragagnolo Neura , Costa Antonio Rosendo da , Jordão Filho José , Almeida Neiva Maria de
Published: February 2023

The goal of this study was to determine the essential fatty acids of the total lipids of the fillet, head and orbital cavity tissue from farmed tambaqui (Colossoma macropomum) fish from a Brazilian Amazon area. The tambaqui were acquired from different fish farms in the Roraima state, located at Western Brazilian Amazon. The meat, the head and the fatty tissue from orbital cavity were dissected for lipid extraction and analysis of fatty acids by gas chromatography. The fatty acids were quantified in mg g-1 of total lipids using C23:0 as an internal standard. The nutritional quality of the lipids was determined by using the atherogenicity and thrombogenicity indices, and also by the ratio between hypocholesterolemic / hypercholesterolemic fatty acids. The orbital cavity tissue had the higher concentration amount of linoleic and α-linolenic acid, whereas the fillet had higher docosahexaenoic acid (DHA). The eicosapentaenoic acid (EPA) concentration was: 1.28, 0.97, 1.71 mg g-1 of total lipids, in the filet, in head, and in orbital cavity tissue, respectively. All essential fatty acids were detected in the three parts analyzed. The nutritional quality of the total lipids from the head and from the orbital cavity tissue was similar to the fillet.
Effects of dietary fiber on performance and egg quality of laying hens at pre-laying and laying peak
Authors: Andrade Pedro Gabriel Carneiro de , Mendonça Marco Antonio de Freitas , Cruz Frank George Guimarães , Rufino João Paulo Ferreira , Silva Fernanda Moura Fernandes , Reis Lucas de Almeida
Published: February 2023

This study aimed to evaluate the effects of different levels of dietary fiber on the performance and egg quality of laying hens at pre-laying and laying peak periods. The experimental period was divided into three periods: pre-laying (16 to 19 weeks of age), the start of laying (20 to 22 weeks of age) and laying peak (23 to 28 weeks of age). The experimental design was completely randomized with treatments constituted by five levels of fiber (2.00, 2.50, 3.00, 3.50, and 4.00%) in the diets, with five replicates (pens) of six birds each, totalling 180 hens. Performance and egg quality results were evaluated by polynomial regression at 5%. Fiber levels were not influenced (p >0.05) the first laying of the hens. However, levels above 2.50% of fiber provided worst (p <0.05) performance results, regardless of the period evaluated. Shortly after the start of laying, higher levels of fiber also caused a linear reduction (p <0.05) on egg weight and percentages of yolk and albumen, and an increase (p <0.05) on eggshells. Higher fiber levels caused a linear reduction (p <0.05) in the quality of the eggs, regardless of the period evaluated. It was concluded that the fiber levels did not influence the start period of the laying. Both pre-laying and start of the laying, levels above 2.5% of fiber caused a gradual worsening in performance. From the start of laying up to laying peak, levels above 2.5% of fiber also caused a gradual worsening in egg quality.
Dr Association of bone morphogenetic protein 15 and growth differentiation factor 9 with litter size in livestock: a review study
Authors: Ajafar Majeed Hameed , Kadhim Alaa Hasan , Al-Thuwaini Tahreer Mohammed , Al-Shuhaib Mohammed Baqur Sahib , Hussein Tamadhur Hani
Published: February 2023

. Litter size is one of the crucial factors in livestock production and is of high economic value, which is affected by ovulation rate, hormones, and growth factors. Growth factors play a multifaceted role in reproductive physiology. This review aims to investigate the association of bone morphogenetic protein 15 (BMP15) and growth differentiation factor 9 (GDF9) with litter size in livestock. The transforming growth factor β (TGF- β) superfamily includes more than 34 members; GDF9 and BMP15 are among the most significant factors for regulating fertility and litter size in most livestock species. Ovarian follicles release BMP15 and GDF9 that are involved in the maturation of primary follicles into the basal form, proliferation of granulosa and theca cells, steroidogenesis, ovulation, and formation of the corpus luteum. Besides, these factors are highly expressed in oocytes and are necessary for female fertility and multiple ovulation in several livestock species. Animals with two inactive copies of these factors are sterile, while those with one inactive copy are fertile. Thus, the present review provides valuable information on the association of BMP15 and GDF9 with litter size in livestock that can be used as biological markers of multiple ovulation or for improving fertility in livestock.
Vermicompost – a Better Organic Manure in Integrated Plant Nutrient System for Vigna radiata (Mung Bean)
Authors: Jeyavaran A. , Bandusekra B. S. , Sivakumar K. , Gunathilake C.
Published: February 2023

The mung bean (Vigna radiata L.) is a member of the Fabaceae family. It is a major grain legume widely farmed in tropical and subtropical regions worldwide. Mung bean is a versatile crop that responds well to fertilizers and low nitrogen requirements due to its leguminous nature. The present experiment evaluated the effects of different types of organic manure on mung bean growth, yield, and physicochemical properties to identify the best integrated plant nutrient management system. There were five treatments; T1 application of inorganic fertilizer (DOAR), T2– application of compost (10 mt/ha) and ¼ DOAR, T3 – application of vermicompost (8 mt/ha) + ¼ DOAR, T4 – application of cow dung (4 mt/ha) + ¼ DOAR and T5 – no application of any fertilizers. Mung bean variety MI-06 was used as genetic material (raw seeding), and organic manure was added at the land preparation, and synthetic fertilizer was added as a split application. The variables such as plant height, number of pods per plant, seed yield, thousand seed weight, moisture content, protein content, and bulk density of the flour were varied among treatments. It was found that there were significant differences among treatments on all parameters except plant height and pH of the flour.. The highest number of seeds per pod, thousand seed weights, and total grain yield were recorded from vermicompost, which was not significantly different from inorganic fertilizer. Significantly lowest bulk density of flour was recorded from inorganic fertilizer, whereas others did not show a statistical difference. Interestingly, the significantly highest protein content was recorded from vermicompost, followed by the inorganic fertilizer. The present study suggested that applying a vermicompos to the integrated plant nutrient mixture could increase the quality and quantity of mung beans, especially yield and protein content.
Abstract 10
Authors: Gora Anamika , Sahlot Rahul , Kumar Anshul , Sharma Balram , Saran Sanjay , Yadav Suchitra
Published: February 2023

Background: Osteosclerosis is a condition characterized by high bone mineral density associated with disorders such as hypoparathyroidism, renal osteodystrophy, fluorosis and osteopetrosis. Hypoparathyroidism and fluorosis are two of the most common diseases causing sclerotic bone disease. Fluorosis also causes secondary hyperparathyroidism and has been implicated in renal dysfunction. Co-Occurrence of these disorders is both rare and confusing.

Case Summary: 42-year-old male, previously diagnosed case of hypoparathyroidism presented with, fixed flexion deformity of the spine and limbs, episode of seizure, recurrent carpopedal spasms and low back ache. On examination there was positive Chvostek’s and trousseau signs, proximal muscle weakness and restriction of movement at both hip and spine, dental examination revealed mottling of without any discernable pitting. On investigation serum calcium was low (5.92 mg/dl), serum phosphorus was high (7.82 mg/dl). Serum PTH and vitamin D levels were 2.9 pg/ml and 26.8 ng/ml respectively. Xray was suggestive of osteopetrosis, DXA SCAN-Left neck femur: +3.8, Lumbar spine: +5.9. On further workup, patients drinking water fluoride content was measured and was found to be 12 ppm over 10 times the recommended WHO limit. The candle wax appearance especially in the tibia also posed melorheosteosis as a potential differential diagnosis but the fact that the patient hailed from the fluoride belt of Rajasthan and other features along with raised fluoride led us to the diagnosis of Hypoparathyroidism with fluorosis and the patient was managed on oral calcium and calcitriol.

Conclusion: Hypoparathyroidism together with fluorosis is a rare entity and timely diagnosis can prevent morbidity and improve the quality of life.