bluuebunny/crossref_metadata_2025 huggingface dataset:
Figure S6 from Single-Cell Immune Competency Signatures Associate with Survival in Phase II GVAX and CRS-207 Randomized Studies in Patients with Metastatic Pancreatic Cancer
Authors: Nair Nitya , Chen Shih-Yu , Lemmens Ed , Chang Serena , Le Dung T. , Jaffee Elizabeth M. , Murphy Aimee , Whiting Chan , Müller Thomas , Brockstedt Dirk G.
Published: April 2023

Cellular biomarkers are independent of treatment in the validation patient cohort
Figure S2 from Single-Cell Immune Competency Signatures Associate with Survival in Phase II GVAX and CRS-207 Randomized Studies in Patients with Metastatic Pancreatic Cancer
Authors: Nair Nitya , Chen Shih-Yu , Lemmens Ed , Chang Serena , Le Dung T. , Jaffee Elizabeth M. , Murphy Aimee , Whiting Chan , Müller Thomas , Brockstedt Dirk G.
Published: April 2023

Expression of additional markers in two candidate immune cell subsets
Supplementary Table S1 from Longitudinal Immune Profiling Reveals Unique Myeloid and T-cell Phenotypes Associated with Spontaneous Immunoediting in a Prostate Tumor Model
Authors: Ager Casey R. , Obradovic Aleksandar Z. , Arriaga Juan M. , Chaimowitz Matthew G. , Califano Andrea , Abate-Shen Cory , Drake Charles G.
Published: April 2023

Supplementary Table S1
Supplementary Figure Legends from A Fusion Protein Complex that Combines IL-12, IL-15, and IL-18 Signaling to Induce Memory-Like NK Cells for Cancer Immunotherapy
Authors: Becker-Hapak Michelle K. , Shrestha Niraj , McClain Ethan , Dee Michael J. , Chaturvedi Pallavi , Leclerc Gilles M. , Marsala Lynne I. , Foster Mark , Schappe Timothy , Tran Jennifer , Desai Sweta , Neal Carly C. , Pence Patrick , Wong Pamela , Wagner Julia A. , Russler-Germain David A. , Zhu Xiaoyun , Spanoudis Catherine M. , Gallo Victor L. , Echeverri Christian A. , Ramirez Laritza L. , You Lijing , Egan Jack O. , Rhode Peter R. , Jiao Jin-an , Muniz Gabriela J. , Jeng Emily K. , Prendes Caitlin A. , Sullivan Ryan P. , Berrien-Elliott Melissa M. , Wong Hing C. , Fehniger Todd A.
Published: April 2023

Legends for Supplementary Figures 1-8 and Supplementary Tables 1-5
Supplementary Figures from Combined CD44- and CD25-Targeted Near-Infrared Photoimmunotherapy Selectively Kills Cancer and Regulatory T Cells in Syngeneic Mouse Cancer Models
Authors: Maruoka Yasuhiro , Furusawa Aki , Okada Ryuhei , Inagaki Fuyuki , Fujimura Daiki , Wakiyama Hiroaki , Kato Takuya , Nagaya Tadanobu , Choyke Peter L. , Kobayashi Hisataka
Published: April 2023

Supplementary figures 1 and 2
Supplementary Figure Legends from Tumor Cell–Intrinsic USP22 Suppresses Antitumor Immunity in Pancreatic Cancer
Authors: Li Jinyang , Yuan Salina , Norgard Robert J. , Yan Fangxue , Yamazoe Taiji , Blanco Andrés , Stanger Ben Z.
Published: April 2023

Legends for Figure S1-4
Supplementary Figures 1-10 from Antitumor Effects of CAR T Cells Redirected to the EDB Splice Variant of Fibronectin
Authors: Wagner Jessica , Wickman Elizabeth , Shaw Timothy I. , Anido Alejandro Allo , Langfitt Deanna , Zhang Jinghui , Porter Shaina N. , Pruett-Miller Shondra M. , Tillman Heather , Krenciute Giedre , Gottschalk Stephen
Published: April 2023

Supplementary Figures 1-10
Supplementary Figures from Control of Metastases via Myeloid CD39 and NK Cell Effector Function
Authors: Yan Juming , Li Xian-Yang , Roman Aguilera Amelia , Xiao Christos , Jacoberger-Foissac Celia , Nowlan Bianca , Robson Simon C. , Beers Courtney , Moesta Achim K. , Geetha Nishamol , Teng Michele W.L. , Smyth Mark J.
Published: April 2023

Supplementary Figures 1-10 + Legends
Supplementary Tables from Activating Mucosal-Associated Invariant T Cells Induces a Broad Antitumor Response
Authors: Ruf Benjamin , Catania Vanessa V. , Wabitsch Simon , Ma Chi , Diggs Laurence P. , Zhang Qianfei , Heinrich Bernd , Subramanyam Varun , Cui Linda L. , Pouzolles Marie , Evans Christine N. , Chari Raj , Sakai Shunsuke , Oh Sangmi , Barry Clifton E. , Barber Daniel L. , Greten Tim F.
Published: April 2023

Supplementary Tables
Supplementary Figures from Sialylation of CD55 by ST3GAL1 Facilitates Immune Evasion in Cancer
Authors: Lin Wen-Der , Fan Tan-Chi , Hung Jung‐Tung , Yeo Hui-Ling , Wang Sheng-Hung , Kuo Chu-Wei , Khoo Kay-Hooi , Pai Li-Mei , Yu John , Yu Alice L.
Published: April 2023

Supplementary figure S1-S5
Supplementary Figures from CD226hiCD8+ T Cells Are a Prerequisite for Anti-TIGIT Immunotherapy
Authors: Jin Hyung-seung , Ko Minkyung , Choi Da-som , Kim June Hyuck , Lee Dong-hee , Kang Seong-Ho , Kim Inki , Lee Hee Jin , Choi Eun Kyung , Kim Kyu-pyo , Yoo Changhoon , Park Yoon
Published: April 2023

Containing Supplementary Figures S1 - S12
Supplementary Table S1 from Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8+ T Cells
Authors: Drijvers Jefte M. , Gillis Jacob E. , Muijlwijk Tara , Nguyen Thao H. , Gaudiano Emily F. , Harris Isaac S. , LaFleur Martin W. , Ringel Alison E. , Yao Cong-Hui , Kurmi Kiran , Juneja Vikram R. , Trombley Justin D. , Haigis Marcia C. , Sharpe Arlene H.
Published: April 2023

Supplementary Table S1
Supplementary Figures from The Ratio of Exhausted to Resident Infiltrating Lymphocytes Is Prognostic for Colorectal Cancer Patient Outcome
Authors: Foroutan Momeneh , Molania Ramyar , Pfefferle Aline , Behrenbruch Corina , Scheer Sebastian , Kallies Axel , Speed Terence P. , Cursons Joseph , Huntington Nicholas D.
Published: April 2023

Supplementary data containing 25 Supp. figures that support the results of the paper.
Table S1, Table S2 from Immunotherapy of Pediatric Solid Tumors: Treatments at a Crossroads, with an Emphasis on Antibodies
Authors: Casey Dana L. , Cheung Nai-Kong V.
Published: April 2023

Supplemental Tables
Supplementary Tables from Mammalian SWI/SNF Complex Genomic Alterations and Immune Checkpoint Blockade in Solid Tumors
Authors: Abou Alaiwi Sarah , Nassar Amin H. , Xie Wanling , Bakouny Ziad , Berchuck Jacob E. , Braun David A. , Baca Sylvan C. , Nuzzo Pier Vitale , Flippot Ronan , Mouhieddine Tarek H. , Spurr Liam F. , Li Yvonne Y. , Li Taiwen , Flaifel Abdallah , Steinharter John A. , Margolis Claire A. , Vokes Natalie I. , Du Heng , Shukla Sachet A. , Cherniack Andrew D. , Sonpavde Guru , Haddad Robert I. , Awad Mark M. , Giannakis Marios , Hodi F. Stephen , Liu X. Shirley , Signoretti Sabina , Kadoch Cigall , Freedman Matthew L. , Kwiatkowski David J. , Van Allen Eliezer M. , Choueiri Toni K.
Published: April 2023

Supplementary Tables
Supplementary Figures Legends from Mammalian SWI/SNF Complex Genomic Alterations and Immune Checkpoint Blockade in Solid Tumors
Authors: Abou Alaiwi Sarah , Nassar Amin H. , Xie Wanling , Bakouny Ziad , Berchuck Jacob E. , Braun David A. , Baca Sylvan C. , Nuzzo Pier Vitale , Flippot Ronan , Mouhieddine Tarek H. , Spurr Liam F. , Li Yvonne Y. , Li Taiwen , Flaifel Abdallah , Steinharter John A. , Margolis Claire A. , Vokes Natalie I. , Du Heng , Shukla Sachet A. , Cherniack Andrew D. , Sonpavde Guru , Haddad Robert I. , Awad Mark M. , Giannakis Marios , Hodi F. Stephen , Liu X. Shirley , Signoretti Sabina , Kadoch Cigall , Freedman Matthew L. , Kwiatkowski David J. , Van Allen Eliezer M. , Choueiri Toni K.
Published: April 2023

Supplementary Figures and Legends for Supplementary Tables
Figure S4 from The Chemokine CX3CL1 Improves Trastuzumab Efficacy in HER2 Low–Expressing Cancer In Vitro and In Vivo
Authors: Dreyer Tobias F. , Kuhn Sabine , Stange Christoph , Heithorst Nadine , Schilling Daniela , Jelsma Jil , Sievert Wolfgang , Seitz Stefanie , Stangl Stefan , Hapfelmeier Alexander , Noske Aurelia , Wege Anja K. , Weichert Wilko , Ruland Jürgen , Schmitt Manfred , Dorn Julia , Kiechle Marion , Reuning Ute , Magdolen Viktor , Multhoff Gabriele , Bronger Holger
Published: April 2023

Impact of soluble CX3CL1 and ADAM17 inhibition by TAPI-2 on NK cell-mediated tumor cell lysis in vitro.
Supplementary Figure S6 from TGFβ Programs Central Memory Differentiation in Ex Vivo–Stimulated Human T Cells
Authors: Dahmani Amina , Janelle Valérie , Carli Cédric , Richaud Manon , Lamarche Caroline , Khalili Myriam , Goupil Mathieu , Bezverbnaya Ksenia , Bramson Jonathan L. , Delisle Jean-Sébastien
Published: April 2023

TGF-b and CAR transduction
Supplementary Figure S4 from TGFβ Programs Central Memory Differentiation in Ex Vivo–Stimulated Human T Cells
Authors: Dahmani Amina , Janelle Valérie , Carli Cédric , Richaud Manon , Lamarche Caroline , Khalili Myriam , Goupil Mathieu , Bezverbnaya Ksenia , Bramson Jonathan L. , Delisle Jean-Sébastien
Published: April 2023

EBNA1-specific T-cell lines
Supplementary Tables and Figures from Differential Expression of CD49a and CD49b Determines Localization and Function of Tumor-Infiltrating CD8+ T Cells
Authors: Melssen Marit M. , Lindsay Robin S. , Stasiak Katarzyna , Rodriguez Anthony B. , Briegel Amanda M. , Cyranowski Salwador , Rutkowski Melanie R. , Conaway Mark R. , Melief Cornelis J.M. , van der Burg Sjoerd H. , Eyo Ukpong , Slingluff Craig L. , Engelhard Victor H.
Published: April 2023

Supplementary Tables S1-S2; Supplementary Figures S1-S10 and Legends for Supplementary Movies 1-3
Supplementary Movie S3 from Differential Expression of CD49a and CD49b Determines Localization and Function of Tumor-Infiltrating CD8+ T Cells
Authors: Melssen Marit M. , Lindsay Robin S. , Stasiak Katarzyna , Rodriguez Anthony B. , Briegel Amanda M. , Cyranowski Salwador , Rutkowski Melanie R. , Conaway Mark R. , Melief Cornelis J.M. , van der Burg Sjoerd H. , Eyo Ukpong , Slingluff Craig L. , Engelhard Victor H.
Published: April 2023

Movement of cells in anti-CD49a treated tumor slices
Supplementary Video 1 from Nutlin-3a Enhances Natural Killer Cell–Mediated Killing of Neuroblastoma by Restoring p53-Dependent Expression of Ligands for NKG2D and DNAM-1 Receptors
Authors: Veneziani Irene , Infante Paola , Ferretti Elisa , Melaiu Ombretta , Battistelli Cecilia , Lucarini Valeria , Compagnone Mirco , Nicoletti Carmine , Castellano Aurora , Petrini Stefania , Ognibene Marzia , Pezzolo Annalisa , Di Marcotullio Lucia , Bei Roberto , Moretta Lorenzo , Pistoia Vito , Fruci Doriana , Barnaba Vincenzo , Locatelli Franco , Cifaldi Loredana
Published: April 2023

Supplementary Video 1
Supplementary Figures 1-8 from Modifications to the Framework Regions Eliminate Chimeric Antigen Receptor Tonic Signaling
Authors: Landoni Elisa , Fucá Giovanni , Wang Jian , Chirasani Venkat R. , Yao Zhiyuan , Dukhovlinova Elena , Ferrone Soldano , Savoldo Barbara , Hong Lee K. , Shou Peishun , Musio Silvia , Padelli Francesco , Finocchiaro Gaetano , Droste Miriam , Kuhlman Brian , Shamshiev Abdijapar , Pellegatta Serena , Dokholyan Nikolay V. , Dotti Gianpietro
Published: April 2023

Supplementary Figures and Legends
Supplementary Figure legend from Nutlin-3a Enhances Natural Killer Cell–Mediated Killing of Neuroblastoma by Restoring p53-Dependent Expression of Ligands for NKG2D and DNAM-1 Receptors
Authors: Veneziani Irene , Infante Paola , Ferretti Elisa , Melaiu Ombretta , Battistelli Cecilia , Lucarini Valeria , Compagnone Mirco , Nicoletti Carmine , Castellano Aurora , Petrini Stefania , Ognibene Marzia , Pezzolo Annalisa , Di Marcotullio Lucia , Bei Roberto , Moretta Lorenzo , Pistoia Vito , Fruci Doriana , Barnaba Vincenzo , Locatelli Franco , Cifaldi Loredana
Published: April 2023

Supplementary Figure legend
Figure S3 from γδ T Cells Support Antigen-Specific αβ T cell–Mediated Antitumor Responses during BCG Treatment for Bladder Cancer
Authors: Ji Niannian , Mukherjee Neelam , Shu Zhen-Ju , Reyes Ryan M. , Meeks Joshua J. , McConkey David J. , Gelfond Jonathan A. , Curiel Tyler J. , Svatek Robert S.
Published: April 2023

Figure S3 - Figure.S3 shows an increase of γδ T cells in tumor-draining lymph nodes in mouse bearing subcutaneous MB49 tumors and depleted of conventional αβ T cells.
Supplementary Data from A Costimulatory CAR Improves TCR-based Cancer Immunotherapy
Authors: Omer Bilal , Cardenas Mara G. , Pfeiffer Thomas , Daum Rachel , Huynh Mai , Sharma Sandhya , Nouraee Nazila , Xie Cicilyn , Tat Candise , Perconti Silvana , Van Pelt Stacey , Scherer Lauren , DeRenzo Chris , Shum Thomas , Gottschalk Stephen , Arber Caroline , Rooney Cliona M.
Published: April 2023

Supplementary Data from A Costimulatory CAR Improves TCR-based Cancer Immunotherapy
Supplementary Data from Exploiting Natural Killer Cell Engagers to Control Pediatric B-cell Precursor Acute Lymphoblastic Leukemia
Authors: Colomar-Carando Natalia , Gauthier Laurent , Merli Pietro , Loiacono Fabrizio , Canevali Paolo , Falco Michela , Galaverna Federica , Rossi Benjamin , Bosco Frédéric , Caratini Mélody , Mingari Maria Cristina , Locatelli Franco , Vivier Eric , Meazza Raffaella , Pende Daniela
Published: April 2023

Supplementary Data from Exploiting Natural Killer Cell Engagers to Control Pediatric B-cell Precursor Acute Lymphoblastic Leukemia
Supplementary Figure 7 from Site-Dependent Immune Escape Due to Impaired Dendritic Cell Cross-Priming
Authors: Diamond Mark S. , Lin Jeffrey H. , Vonderheide Robert H.
Published: April 2023

Supplementary Figure 7
Supplementary Figure 3 from Site-Dependent Immune Escape Due to Impaired Dendritic Cell Cross-Priming
Authors: Diamond Mark S. , Lin Jeffrey H. , Vonderheide Robert H.
Published: April 2023

Supplementary Figure 3
Supplementary Data from Modified Manufacturing Process Modulates CD19CAR T-cell Engraftment Fitness and Leukemia-Free Survival in Pediatric and Young Adult Subjects
Authors: Ceppi Francesco , Wilson Ashley L. , Annesley Colleen , Kimmerly Gabriella R. , Summers Corinne , Brand Adam , Seidel Kristy , Wu Qian Vicky , Beebe Adam , Brown Christopher , Mgebroff Stephanie , Lindgren Catherine , Rawlings-Rhea Stephanie D. , Huang Wenjun , Pulsipher Michael A. , Wayne Alan S. , Park Julie R. , Jensen Michael C. , Gardner Rebecca A.
Published: April 2023

Supplementary Data from Modified Manufacturing Process Modulates CD19CAR T-cell Engraftment Fitness and Leukemia-Free Survival in Pediatric and Young Adult Subjects
Supplementary Figure from Molecular Signature of Tumor-Associated High Endothelial Venules That Can Predict Breast Cancer Survival
Authors: Sawada Junko , Hiraoka Nobuyoshi , Qi Rongsu , Jiang Lu , Fournier-Goss Ashley E. , Yoshida Masayuki , Kawashima Hiroto , Komatsu Masanobu
Published: April 2023

Supplementary Figure from Molecular Signature of Tumor-Associated High Endothelial Venules That Can Predict Breast Cancer Survival
Supplementary Table S3 from APOBEC Mutagenesis Inhibits Breast Cancer Growth through Induction of T cell–Mediated Antitumor Immune Responses
Authors: DiMarco Ashley V. , Qin Xiaodi , McKinney Brock J. , Garcia Nina Marie G. , Van Alsten Sarah C. , Mendes Elizabeth A. , Force Jeremy , Hanks Brent A. , Troester Melissa A. , Owzar Kouros , Xie Jichun , Alvarez James V.
Published: April 2023

Supplementary Table S3
Supplementary Table S2 from APOBEC Mutagenesis Inhibits Breast Cancer Growth through Induction of T cell–Mediated Antitumor Immune Responses
Authors: DiMarco Ashley V. , Qin Xiaodi , McKinney Brock J. , Garcia Nina Marie G. , Van Alsten Sarah C. , Mendes Elizabeth A. , Force Jeremy , Hanks Brent A. , Troester Melissa A. , Owzar Kouros , Xie Jichun , Alvarez James V.
Published: April 2023

Supplementary Table S2
Supplementary Data from The Tumor Microenvironment of Clear-Cell Ovarian Cancer
Authors: Devlin Michael-John , Miller Rowan , Laforets Florian , Kotantaki Panoraia , Garsed Dale W. , Kristeleit Rebecca , Bowtell David D. , McDermott Jacqueline , Maniati Eleni , Balkwill Frances R.
Published: April 2023

Supplementary Data from The Tumor Microenvironment of Clear-Cell Ovarian Cancer
Supplementary Data from ICBatlas: A Comprehensive Resource for Depicting Immune Checkpoint Blockade Therapy Characteristics from Transcriptome Profiles
Authors: Yang Mei , Miao Ya-Ru , Xie Gui-Yan , Luo Mei , Hu Hui , Kwok Hang Fai , Feng Jian , Guo An-Yuan
Published: April 2023

Supplementary Data from ICBatlas: A Comprehensive Resource for Depicting Immune Checkpoint Blockade Therapy Characteristics from Transcriptome Profiles
Supplementary Data files from Hippo Signaling Pathway Regulates Cancer Cell–Intrinsic MHC-II Expression
Authors: Zeng Zexian , Gu Shengqing Stan , Ouardaoui Nofal , Tymm Carly , Yang Lin , Wong Cheryl J. , Li Dian , Zhang Wubing , Wang Xiaoqing , Weirather Jason L. , Rodig Scott J. , Hodi F. Stephen , Brown Myles , Liu X. Shirley
Published: April 2023

Figure S1 and Figure S2
Supplementary Figure from Intravesical VAX014 Synergizes with PD-L1 Blockade to Enhance Local and Systemic Control of Bladder Cancer
Authors: Tsuji Shingo , Reil Katherine , Nelson Kinsey , Proclivo Veronica H. , McGuire Kathleen L. , Giacalone Matthew J.
Published: April 2023

Supplementary Figure from Intravesical VAX014 Synergizes with PD-L1 Blockade to Enhance Local and Systemic Control of Bladder Cancer
Supplementary Figure from Long Noncoding RNA MIR4435-2HG Suppresses Colorectal Cancer Initiation and Progression By Reprogramming Neutrophils
Authors: Yu Hongfei , Chen Chaoyi , Han Fengyan , Tang Jinlong , Deng Mengli , Niu Yumiao , Lai Maode , Zhang Honghe
Published: April 2023

Supplementary Figure from Long Noncoding RNA MIR4435-2HG Suppresses Colorectal Cancer Initiation and Progression By Reprogramming Neutrophils
Supplementary Data from Activation of Tumor-Cell STING Primes NK-Cell Therapy
Authors: Knelson Erik H. , Ivanova Elena V. , Tarannum Mubin , Campisi Marco , Lizotte Patrick H. , Booker Matthew A. , Ozgenc Ismail , Noureddine Moataz , Meisenheimer Brittany , Chen Minyue , Piel Brandon , Spicer Nathaniel , Obua Bonje , Messier Cameron M. , Shannon Erin , Mahadevan Navin R. , Tani Tetsuo , Schol Pieter J. , Lee-Hassett Anna M. , Zlota Ari , Vo Ha V. , Ha Minh , Bertram Arrien A. , Han Saemi , Thai Tran C. , Gustafson Corinne E. , Venugopal Kartika , Haggerty Timothy J. , Albertson Thomas P. , Hartley Antja-Voy , Eser Pinar O. , Li Ze-Hua , Cañadas Israel , Vivero Marina , De Rienzo Assunta , Richards William G. , Abu-Yousif Adnan O. , Appleman Vicky A. , Gregory Richard C. , Parent Alexander , Lineberry Neil , Smith Eric L. , Jänne Pasi A. , Miret Juan J. , Tolstorukov Michael Y. , Romee Rizwan , Paweletz Cloud P. , Bueno Raphael , Barbie David A.
Published: April 2023

Supplementary Data from Activation of Tumor-Cell STING Primes NK-Cell Therapy
Supplementary Data from CD8+ T-cell Responses Are Boosted by Dual PD-1/VEGFR2 Blockade after EGFR Inhibition in Egfr-Mutant Lung Cancer
Authors: Nishii Kazuya , Ohashi Kadoaki , Tomida Shuta , Nakasuka Takamasa , Hirabae Atsuko , Okawa Sachi , Nishimura Jun , Higo Hisao , Watanabe Hiromi , Kano Hirohisa , Ando Chihiro , Makimoto Go , Ninomiya Kiichiro , Kato Yuka , Kubo Toshio , Ichihara Eiki , Hotta Katsuyuki , Tabata Masahiro , Toyooka Shinichi , Udono Heiichiro , Maeda Yoshinobu , Kiura Katsuyuki
Published: April 2023

Supplementary Data from CD8+ T-cell Responses Are Boosted by Dual PD-1/VEGFR2 Blockade after EGFR Inhibition in Egfr-Mutant Lung Cancer
Figure S5 from Extracellular Vesicle–Packaged circATP2B4 Mediates M2 Macrophage Polarization via miR-532-3p/SREBF1 Axis to Promote Epithelial Ovarian Cancer Metastasis
Authors: Wang Fang , Niu Yuequn , Chen Kelie , Yuan Xiaoyu , Qin Yuheng , Zheng Fang , Cui Zhenyan , Lu Weiguo , Wu Yihua , Xia Dajing
Published: April 2023

Supplementary Figure S5
Figure S4 from Extracellular Vesicle–Packaged circATP2B4 Mediates M2 Macrophage Polarization via miR-532-3p/SREBF1 Axis to Promote Epithelial Ovarian Cancer Metastasis
Authors: Wang Fang , Niu Yuequn , Chen Kelie , Yuan Xiaoyu , Qin Yuheng , Zheng Fang , Cui Zhenyan , Lu Weiguo , Wu Yihua , Xia Dajing
Published: April 2023

Supplementary Figure S4
Supplementary Table S1 from Radiofrequency Ablation Remodels the Tumor Microenvironment and Promotes Neutrophil-Mediated Abscopal Immunomodulation in Pancreatic Cancer
Authors: Faraoni Erika Y. , O'Brien Baylee J. , Strickland Lincoln N. , Osborn Baron K. , Mota Victoria , Chaney Jarod , Atkins Constance Lynn , Cen Putao , Rowe Julie , Cardenas Jessica , Poulsen Kyle L. , Wray Curtis J. , Thosani Nirav C. , Bailey-Lundberg Jennifer M.
Published: April 2023

Supplementary Table S1
Supplementary Data from Radiofrequency Ablation Remodels the Tumor Microenvironment and Promotes Neutrophil-Mediated Abscopal Immunomodulation in Pancreatic Cancer
Authors: Faraoni Erika Y. , O'Brien Baylee J. , Strickland Lincoln N. , Osborn Baron K. , Mota Victoria , Chaney Jarod , Atkins Constance Lynn , Cen Putao , Rowe Julie , Cardenas Jessica , Poulsen Kyle L. , Wray Curtis J. , Thosani Nirav C. , Bailey-Lundberg Jennifer M.
Published: April 2023

Supplementary Figures
Supplementary Figures from HRS Regulates Small Extracellular Vesicle PD-L1 Secretion and Is Associated with Anti–PD-1 Treatment Efficacy
Authors: Xiao Bo-Lin , Wang Xiao-Le , Xia Hou-Fu , Zhang Lin-Zhou , Wang Kui-Ming , Chen Zhuo-Kun , Zhong Ya-Hua , Jiang Huan-Gang , Zhou Fu-Xiang , Wang Wei , Chen Gai-Li , Chen Gang
Published: April 2023

Supplementary Figures S1-S7
Supplementary Data from Subcapsular Sinus Macrophages Promote Melanoma Metastasis to the Sentinel Lymph Nodes via an IL1α–STAT3 Axis
Authors: Virgilio Tommaso , Bordini Joy , Cascione Luciano , Sartori Giulio , Latino Irene , Molina Romero Daniel , Leoni Cristina , Akhmedov Murodzhon , Rinaldi Andrea , Arribas Alberto J. , Morone Diego , Seyed Jafari S. Morteza , Bersudsky Marina , Ottolenghi Aner , Kwee Ivo , Chiaravalli Anna Maria , Sessa Fausto , Hunger Robert E. , Bruno Antonino , Mortara Lorenzo , Voronov Elena , Monticelli Silvia , Apte Ron N. , Bertoni Francesco , Gonzalez Santiago F.
Published: April 2023

Supplementary Data from Subcapsular Sinus Macrophages Promote Melanoma Metastasis to the Sentinel Lymph Nodes via an IL1α–STAT3 Axis
Supplementary Data from Intratumoral Gene Transfer of mRNAs Encoding IL12 in Combination with Decoy-Resistant IL18 Improves Local and Systemic Antitumor Immunity
Authors: Cirella Assunta , Bolaños Elixabet , Di Trani Claudia Augusta , de Andrea Carlos E. , Sánchez-Gregorio Sandra , Etxeberria Iñaki , Gonzalez-Gomariz Jose , Olivera Irene , Brocco Davide , Glez-Vaz Javier , Luri-Rey Carlos , Azpilikueta Arantza , Rodríguez Inmaculada , Fernandez-Sendín Myriam , Egea Josune , Eguren Iñaki , Sanmamed Miguel F. , Palencia Belen , Teijeira Alvaro , Berraondo Pedro , Melero Ignacio
Published: April 2023

Supplementary figures 1-8 and supplementary table 1
Supplementary Tables S1-S3 from Enhancing the Antitumor Immunity of T Cells by Engineering the Lipid-Regulatory Site of the TCR/CD3 Complex
Authors: Liang Wenhua , Yi Ruirong , Wang Weifang , Shi Yiwei , Zhang Jiqin , Xu Xiang , Wang Qingcan , Liu Mingyao , Wang Feng
Published: April 2023

Supplementary Tables S1-S3
Supplementary Figures and Tables S1 and S3 from Infiltration of Tumors Is Regulated by T cell–Intrinsic Nitric Oxide Synthesis
Authors: Cunha Pedro P. , Bargiela David , Minogue Eleanor , Krause Lena C.M. , Barbieri Laura , Brombach Carolin , Gojkovic Milos , Marklund Emilia , Pietsch Sandra , Foskolou Iosifina , Branco Cristina M. , Veliça Pedro , Johnson Randall S.
Published: April 2023

Supplementary Figures S1-S6, Supplementary Tables S1 and S3, and uncropped western blot images. 
Supplementary Figures S1-S8 from Enhancing the Antitumor Immunity of T Cells by Engineering the Lipid-Regulatory Site of the TCR/CD3 Complex
Authors: Liang Wenhua , Yi Ruirong , Wang Weifang , Shi Yiwei , Zhang Jiqin , Xu Xiang , Wang Qingcan , Liu Mingyao , Wang Feng
Published: April 2023

All supplementary figures S1-S8
Supplementary Data from The Conventional Dendritic Cell 1 Subset Primes CD8+ T Cells and Traffics Tumor Antigen to Drive Antitumor Immunity in the Brain
Authors: Bowman-Kirigin Jay A. , Desai Rupen , Saunders Brian T. , Wang Anthony Z. , Schaettler Maximilian O. , Liu Connor J. , Livingstone Alexandra J. , Kobayashi Dale K. , Durai Vivek , Kretzer Nicole M. , Zipfel Gregory J. , Leuthardt Eric C. , Osbun Joshua W. , Chicoine Michael R. , Kim Albert H. , Murphy Kenneth M. , Johanns Tanner M. , Zinselmeyer Bernd H. , Dunn Gavin P.
Published: April 2023

Supplementary Figures and Tables.
Supplementary Data from Self-Renewing CD8+ T-cell Abundance in Blood Associates with Response to Immunotherapy
Authors: Maniar Rohan , Wang Peter H. , Washburn Robert S. , Kratchmarov Radomir , Coley Shana M. , Saqi Anjali , Pan Samuel S. , Hu Jianhua , Shu Catherine A. , Rizvi Naiyer A. , Henick Brian S. , Reiner Steven L.
Published: April 2023

Supplementary Figs. S1-S5
Supplementary Data S1 from Rational Protein Design Yields a CD20 CAR with Superior Antitumor Efficacy Compared with CD19 CAR
Authors: Chen Ximin , Chen Laurence C. , Khericha Mobina , Meng Xiangzhi , Salvestrini Emma , Shafer Amanda , Iyer Neha , Alag Anya S. , Ding Yunfeng , Nicolaou Demetri M. , Chen Yvonne Y.
Published: April 2023

A curated list of 2493 T-cell–relevant gene sets selected from current Molecular Signatures Database (MSigDB) gene sets.
Data from IL18 Receptor Signaling Regulates Tumor-Reactive CD8+ T-cell Exhaustion via Activation of the IL2/STAT5/mTOR Pathway in a Pancreatic Cancer Model
Authors: Lutz Veronika , Hellmund Veronique M. , Picard Felix S.R. , Raifer Hartmann , Ruckenbrod Teresa , Klein Matthias , Bopp Tobias , Savai Rajkumar , Duewell Peter , Keber Corinna U. , Weigert Andreas , Chung Ho-Ryun , Buchholz Malte , Menke André , Gress Thomas M. , Huber Magdalena , Bauer Christian
Published: April 2023

Abstract
Intratumoral cytotoxic CD8+ T cells (CTL) enter a dysfunctional state characterized by expression of coinhibitory receptors, loss of effector function, and changes in the transcriptional landscape. Even though several regulators of T-cell exhaustion have been identified, the molecular mechanisms inducing T-cell exhaustion remain unclear. Here, we show that IL18 receptor (IL18R) signaling induces CD8+ T-cell exhaustion in a murine pancreatic cancer model. Adoptive transfer of Il18r−/− OT-1 CD8+ CTLs resulted in enhanced rejection of subcutaneous tumors expressing ovalbumin (OVA) as a model antigen (PancOVA), compared with wild-type OT-1 CTLs. Transferred intratumoral IL18R-deficient CTLs expressed higher levels of effector cytokines TNF and IFNγ and had reduced expression of coinhibitory receptors (PD-1, TIM-3, 2B4, LAG-3) and the transcription factors Eomes and TOX. Lower expression of coinhibitory receptors and TOX on IL18R-deficient versus IL18R-sufficient CD8+ T cells were confirmed in an orthotopic KPC model. IL18R-induced T-cell exhaustion was regulated by IL2/STAT5 and AKT/mTOR pathways, as demonstrated in an in vitro exhaustion assay. Concordantly, mice deficient in NLRP3, the molecular complex activating IL18, had decreased expression of coinhibitory receptors on intratumoral T cells and similar changes in signaling pathways at the transcriptome level. Thus, molecular pathways promoting T-cell exhaustion indicate an involvement of an NLRP3-expressing tumor microenvironment, which mediates IL18 release. The Cancer Genome Atlas analysis of patients with pancreatic carcinoma showed an association between NLRP3-mediated IL18 signaling and shorter survival. These findings indicate NLRP3-mediated IL18R signaling as a regulator of intratumoral T-cell exhaustion and a possible target for immunotherapy.

See related Spotlight by Stromnes, p. 400
Data from Tumor Cell–Derived Microparticles Induced by Methotrexate Augment T-cell Antitumor Responses by Downregulating Expression of PD-1 in Neutrophils
Authors: Xu Pingwei , Zhang Xiaojie , Chen Kai , Zhu Meng , Jia Ru , Zhou Qingwei , Yang Jintao , Dai Juqin , Jin Yuepeng , Shi Keqing
Published: April 2023

Abstract
Neutrophils act as a “double-edged sword” in the tumor microenvironment by either supporting or suppressing tumor progression. Thus, eliciting a neutrophil antitumor response remains challenging. Here, we showed that tumor cell–derived microparticles induced by methotrexate (MTX-MP) acts as an immunotherapeutic agent to activate neutrophils, increasing the tumor-killing effect of the cells and augmenting T-cell antitumor responses. We found that lactate induced tumor-associated neutrophils to elevate expression of programmed cell death protein 1 (PD-1) and that PD-1+ neutrophils had the properties of N2 neutrophils and suppressed T-cell activation through PD-1/programmed death-ligand 1 (PD-L1) signaling. By performing ex vivo experiments, we found that MTX-MPs–activated neutrophils had reduced surface expression of PD-1 as a result of PD-1 internalization and degradation in the lysosomes, leading to the cells showing a decreased capacity to suppress T-cell responses. In addition, we also found that MTX-MP–activated neutrophils released neutrophil elastase which could kill tumor cells and disrupt tumor stroma, leading to increased T-cell infiltration. Furthermore, using a combination of anti–PD-L1 and MTX-MPs, we observed that long-term survival increased in a mouse model of lung cancer. Collectively, these findings highlight the potential use of a combination of anti–PD-L1 and MTX-MPs to enhance the therapeutic effect of anti–PD-L1 alone.
Supplementary Data from An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities
Authors: Flümann Ruth , Rehkämper Tim , Nieper Pascal , Pfeiffer Pauline , Holzem Alessandra , Klein Sebastian , Bhatia Sanil , Kochanek Moritz , Kisis Ilmars , Pelzer Benedikt W. , Ahlert Heinz , Hauer Julia , da Palma Guerreiro Alexandra , Ryan Jeremy A. , Reimann Maurice , Riabinska Arina , Wiederstein Janica , Krüger Marcus , Deckert Martina , Altmüller Janine , Klatt Andreas R. , Frenzel Lukas P. , Pasqualucci Laura , Béguelin Wendy , Melnick Ari M. , Sander Sandrine , Montesinos-Rongen Manuel , Brunn Anna , Lohneis Philipp , Büttner Reinhard , Kashkar Hamid , Borkhardt Arndt , Letai Anthony , Persigehl Thorsten , Peifer Martin , Schmitt Clemens A. , Reinhardt Hans Christian , Knittel Gero
Published: April 2023

Figures S1 - S8
Supplementary Figure 9 from Aging of Preleukemic Thymocytes Drives CpG Island Hypermethylation in T-cell Acute Lymphoblastic Leukemia
Authors: Roels Juliette , Thénoz Morgan , Szarzyńska Bronisława , Landfors Mattias , De Coninck Stien , Demoen Lisa , Provez Lien , Kuchmiy Anna , Strubbe Steven , Reunes Lindy , Pieters Tim , Matthijssens Filip , Van Loocke Wouter , Erarslan-Uysal Büşra , Richter-Pechańska Paulina , Declerck Ken , Lammens Tim , De Moerloose Barbara , Deforce Dieter , Van Nieuwerburgh Filip , Cheung Laurence C. , Kotecha Rishi S. , Mansour Marc R. , Ghesquière Bart , Van Camp Guy , Berghe Wim Vanden , Kowalczyk Jerzy R. , Szczepański Tomasz , Davé Utpal P. , Kulozik Andreas E. , Goossens Steven , Curtis David J. , Taghon Tom , Dawidowska Małgorzata , Degerman Sofie , Van Vlierberghe Pieter
Published: April 2023

Supplementary Figure 9
Supplementary Figure 8 from Aging of Preleukemic Thymocytes Drives CpG Island Hypermethylation in T-cell Acute Lymphoblastic Leukemia
Authors: Roels Juliette , Thénoz Morgan , Szarzyńska Bronisława , Landfors Mattias , De Coninck Stien , Demoen Lisa , Provez Lien , Kuchmiy Anna , Strubbe Steven , Reunes Lindy , Pieters Tim , Matthijssens Filip , Van Loocke Wouter , Erarslan-Uysal Büşra , Richter-Pechańska Paulina , Declerck Ken , Lammens Tim , De Moerloose Barbara , Deforce Dieter , Van Nieuwerburgh Filip , Cheung Laurence C. , Kotecha Rishi S. , Mansour Marc R. , Ghesquière Bart , Van Camp Guy , Berghe Wim Vanden , Kowalczyk Jerzy R. , Szczepański Tomasz , Davé Utpal P. , Kulozik Andreas E. , Goossens Steven , Curtis David J. , Taghon Tom , Dawidowska Małgorzata , Degerman Sofie , Van Vlierberghe Pieter
Published: April 2023

Supplementary Figure 8
Supplementary Figure 13 from Aging of Preleukemic Thymocytes Drives CpG Island Hypermethylation in T-cell Acute Lymphoblastic Leukemia
Authors: Roels Juliette , Thénoz Morgan , Szarzyńska Bronisława , Landfors Mattias , De Coninck Stien , Demoen Lisa , Provez Lien , Kuchmiy Anna , Strubbe Steven , Reunes Lindy , Pieters Tim , Matthijssens Filip , Van Loocke Wouter , Erarslan-Uysal Büşra , Richter-Pechańska Paulina , Declerck Ken , Lammens Tim , De Moerloose Barbara , Deforce Dieter , Van Nieuwerburgh Filip , Cheung Laurence C. , Kotecha Rishi S. , Mansour Marc R. , Ghesquière Bart , Van Camp Guy , Berghe Wim Vanden , Kowalczyk Jerzy R. , Szczepański Tomasz , Davé Utpal P. , Kulozik Andreas E. , Goossens Steven , Curtis David J. , Taghon Tom , Dawidowska Małgorzata , Degerman Sofie , Van Vlierberghe Pieter
Published: April 2023

Supplementary Figure 13
Supplementary Figure 11 from Aging of Preleukemic Thymocytes Drives CpG Island Hypermethylation in T-cell Acute Lymphoblastic Leukemia
Authors: Roels Juliette , Thénoz Morgan , Szarzyńska Bronisława , Landfors Mattias , De Coninck Stien , Demoen Lisa , Provez Lien , Kuchmiy Anna , Strubbe Steven , Reunes Lindy , Pieters Tim , Matthijssens Filip , Van Loocke Wouter , Erarslan-Uysal Büşra , Richter-Pechańska Paulina , Declerck Ken , Lammens Tim , De Moerloose Barbara , Deforce Dieter , Van Nieuwerburgh Filip , Cheung Laurence C. , Kotecha Rishi S. , Mansour Marc R. , Ghesquière Bart , Van Camp Guy , Berghe Wim Vanden , Kowalczyk Jerzy R. , Szczepański Tomasz , Davé Utpal P. , Kulozik Andreas E. , Goossens Steven , Curtis David J. , Taghon Tom , Dawidowska Małgorzata , Degerman Sofie , Van Vlierberghe Pieter
Published: April 2023

Supplementary Figure 11
Supplementary Figure 1 from Aging of Preleukemic Thymocytes Drives CpG Island Hypermethylation in T-cell Acute Lymphoblastic Leukemia
Authors: Roels Juliette , Thénoz Morgan , Szarzyńska Bronisława , Landfors Mattias , De Coninck Stien , Demoen Lisa , Provez Lien , Kuchmiy Anna , Strubbe Steven , Reunes Lindy , Pieters Tim , Matthijssens Filip , Van Loocke Wouter , Erarslan-Uysal Büşra , Richter-Pechańska Paulina , Declerck Ken , Lammens Tim , De Moerloose Barbara , Deforce Dieter , Van Nieuwerburgh Filip , Cheung Laurence C. , Kotecha Rishi S. , Mansour Marc R. , Ghesquière Bart , Van Camp Guy , Berghe Wim Vanden , Kowalczyk Jerzy R. , Szczepański Tomasz , Davé Utpal P. , Kulozik Andreas E. , Goossens Steven , Curtis David J. , Taghon Tom , Dawidowska Małgorzata , Degerman Sofie , Van Vlierberghe Pieter
Published: April 2023

Supplementary Figure 1
Supplementary Table 1 from SIRT5 Is a Druggable Metabolic Vulnerability in Acute Myeloid Leukemia
Authors: Yan Dongqing , Franzini Anca , Pomicter Anthony D. , Halverson Brayden J. , Antelope Orlando , Mason Clinton C. , Ahmann Jonathan M. , Senina Anna V. , Vellore Nadeem A. , Jones Courtney L. , Zabriskie Matthew S. , Than Hein , Xiao Michael J. , van Scoyk Alexandria , Patel Ami B. , Clair Phillip M. , Heaton William L. , Owen Shawn C. , Andersen Joshua L. , Egbert Christina M. , Reisz Julie A. , D'Alessandro Angelo , Cox James E. , Gantz Kevin C. , Redwine Hannah M. , Iyer Siddharth M. , Khorashad Jamshid S. , Rajabi Nima , Olsen Christian A. , O'Hare Thomas , Deininger Michael W.
Published: April 2023

Patient sample information.
Supplemental Table 3A&3B from Predictors of Humoral Response to SARS-CoV-2 Vaccination after Hematopoietic Cell Transplantation and CAR T-cell Therapy
Authors: Tamari Roni , Politikos Ioannis , Knorr David A. , Vardhana Santosha A. , Young Jennifer C. , Marcello LeeAnn T. , Doddi Sital , Devlin Sean M. , Ramanathan Lakshmi V. , Pessin Melissa S. , Dunn Erica , Palazzo Meighan , Bravo Christina D. , Papanicolaou Genovefa A. , Kamboj Mini , Perales Miguel Angel , Chung David J. , Shah Gunjan L.
Published: April 2023

3A: Anti-SARS-CoV-2 spike IgG titers by different cutoffs Supplemental Table 3B: Neutralization Ab >30% threshold when using different cutoffs of anti-SARS-CoV-2 spike IgG response
Supplementary Figures S1-S11 from ZBTB33 Is Mutated in Clonal Hematopoiesis and Myelodysplastic Syndromes and Impacts RNA Splicing
Authors: Beauchamp Ellen M. , Leventhal Matthew , Bernard Elsa , Hoppe Emma R. , Todisco Gabriele , Creignou Maria , Gallì Anna , Castellano Cecilia A. , McConkey Marie , Tarun Akansha , Wong Waihay , Schenone Monica , Stanclift Caroline , Tanenbaum Benjamin , Malolepsza Edyta , Nilsson Björn , Bick Alexander G. , Weinstock Joshua S. , Miller Mendy , Niroula Abhishek , Dunford Andrew , Taylor-Weiner Amaro , Wood Timothy , Barbera Alex , Anand Shankara , Psaty Bruce M. , Desai Pinkal , Cho Michael H. , Johnson Andrew D. , Loos Ruth , MacArthur Daniel G. , Lek Monkol , Neuberg Donna S. , Lage Kasper , Carr Steven A. , Hellstrom-Lindberg Eva , Malcovati Luca , Papaemmanuil Elli , Stewart Chip , Getz Gad , Bradley Robert K. , Jaiswal Siddhartha , Ebert Benjamin L.
Published: April 2023

Supplementary Figures S1-S11
Supplementary Data from Machine Learning of Bone Marrow Histopathology Identifies Genetic and Clinical Determinants in Patients with MDS
Authors: Brück Oscar E. , Lallukka-Brück Susanna E. , Hohtari Helena R. , Ianevski Aleksandr , Ebeling Freja T. , Kovanen Panu E. , Kytölä Soili I. , Aittokallio Tero A. , Ramos Pedro M. , Porkka Kimmo V. , Mustjoki Satu M.
Published: April 2023

Supplementary Data
Supplementary Table S2 from Lysine Demethylase 5A Is Required for MYC-Driven Transcription in Multiple Myeloma
Authors: Ohguchi Hiroto , Park Paul M.C. , Wang Tingjian , Gryder Berkley E. , Ogiya Daisuke , Kurata Keiji , Zhang Xiaofeng , Li Deyao , Pei Chengkui , Masuda Takeshi , Johansson Catrine , Wimalasena Virangika K. , Kim Yong , Hino Shinjiro , Usuki Shingo , Kawano Yawara , Samur Mehmet K. , Tai Yu-Tzu , Munshi Nikhil C. , Matsuoka Masao , Ohtsuki Sumio , Nakao Mitsuyoshi , Minami Takashi , Lauberth Shannon , Khan Javed , Oppermann Udo , Durbin Adam D. , Anderson Kenneth C. , Hideshima Teru , Qi Jun
Published: April 2023

Supplementary Table S2 shows the ChIP-seq data with the peaks significantly overlap with KDM5A ChIP-seq peaks MM1S
Supplementary Figure from Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia
Authors: Umeda Masayuki , Ma Jing , Huang Benjamin J. , Hagiwara Kohei , Westover Tamara , Abdelhamed Sherif , Barajas Juan M. , Thomas Melvin E. , Walsh Michael P. , Song Guangchun , Tian Liqing , Liu Yanling , Chen Xiaolong , Kolekar Pandurang , Tran Quang , Foy Scott G. , Maciaszek Jamie L. , Kleist Andrew B. , Leonti Amanda R. , Ju Bengsheng , Easton John , Wu Huiyun , Valentine Virginia , Valentine Marcus B. , Liu Yen-Chun , Ries Rhonda E. , Smith Jenny L. , Parganas Evan , Iacobucci Ilaria , Hiltenbrand Ryan , Miller Jonathan , Myers Jason R. , Rampersaud Evadnie , Rahbarinia Delaram , Rusch Michael , Wu Gang , Inaba Hiroto , Wang Yi-Cheng , Alonzo Todd A. , Downing James R. , Mullighan Charles G. , Pounds Stanley , Babu M. Madan , Zhang Jinghui , Rubnitz Jeffrey E. , Meshinchi Soheil , Ma Xiaotu , Klco Jeffery M.
Published: April 2023

Supplementary Figure from Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia
Supplementary Table from The Cell Type–Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and TET2-Mutant Preleukemia
Authors: Nakauchi Yusuke , Azizi Armon , Thomas Daniel , Corces M. Ryan , Reinisch Andreas , Sharma Rajiv , Cruz Hernandez David , Köhnke Thomas , Karigane Daiki , Fan Amy , Martinez-Krams Daniel , Stafford Melissa , Kaur Satinder , Dutta Ritika , Phan Paul , Ediriwickrema Asiri , McCarthy Erin , Ning Yuhong , Phillips Tierney , Ellison Christopher K. , Guler Gulfem D. , Bergamaschi Anna , Ku Chin-Jen , Levy Samuel , Majeti Ravindra
Published: April 2023

Supplementary Table from The Cell Type–Specific 5hmC Landscape and Dynamics of Healthy Human Hematopoiesis and TET2-Mutant Preleukemia
Supplementary Table S3 from Extracellular Vesicle Secretion by Leukemia Cells In Vivo Promotes CLL Progression by Hampering Antitumor T-cell Responses
Authors: Gargiulo Ernesto , Viry Elodie , Morande Pablo Elías , Largeot Anne , Gonder Susanne , Xian Feng , Ioannou Nikolaos , Benzarti Mohaned , Kleine Borgmann Felix Bruno , Mittelbronn Michel , Dittmar Gunnar , Nazarov Petr V. , Meiser Johannes , Stamatopoulos Basile , Ramsay Alan G. , Moussay Etienne , Paggetti Jérôme
Published: April 2023

Supplemental Table S3 - Patient clinical information
Supplementary Table 3 from ETV6 Deficiency Unlocks ERG-Dependent Microsatellite Enhancers to Drive Aberrant Gene Activation in B-Lymphoblastic Leukemia
Authors: Kodgule Rohan , Goldman Joshua W. , Monovich Alexander C. , Saari Travis , Aguilar Athalee R. , Hall Cody N. , Rajesh Niharika , Gupta Juhi , Chu Shih-Chun A. , Ye Li , Gurumurthy Aishwarya , Iyer Ashwin , Brown Noah A. , Chiang Mark Y. , Cieslik Marcin P. , Ryan Russell J.H.
Published: April 2023

Supplementary Table 3 summarizes TF ChIP-Seq results and motif enrichment statistics
Table S5 from Distinct Genetically Determined Origins of Myd88/BCL2-Driven Aggressive Lymphoma Rationalize Targeted Therapeutic Intervention Strategies
Authors: Flümann Ruth , Hansen Julia , Pelzer Benedikt W. , Nieper Pascal , Lohmann Tim , Kisis Ilmars , Riet Tobias , Kohlhas Viktoria , Nguyen Phuong-Hien , Peifer Martin , Abedpour Nima , Bosco Graziella , Thomas Roman K. , Kochanek Moritz , Knüfer Jacqueline , Jonigkeit Lorenz , Beleggia Filippo , Holzem Alessandra , Büttner Reinhard , Lohneis Philipp , Meinel Jörn , Ortmann Monika , Persigehl Thorsten , Hallek Michael , Calado Dinis Pedro , Chmielewski Markus , Klein Sebastian , Göthert Joachim R. , Chapuy Bjoern , Zevnik Branko , Wunderlich F. Thomas , von Tresckow Bastian , Jachimowicz Ron D. , Melnick Ari M. , Reinhardt Hans Christian , Knittel Gero
Published: April 2023

Table S5 contains statistical values of gene set enrichment analyses of the KEGG, BIOCARTA and HALLMARK gene set collections.
Table S3 from Distinct Genetically Determined Origins of Myd88/BCL2-Driven Aggressive Lymphoma Rationalize Targeted Therapeutic Intervention Strategies
Authors: Flümann Ruth , Hansen Julia , Pelzer Benedikt W. , Nieper Pascal , Lohmann Tim , Kisis Ilmars , Riet Tobias , Kohlhas Viktoria , Nguyen Phuong-Hien , Peifer Martin , Abedpour Nima , Bosco Graziella , Thomas Roman K. , Kochanek Moritz , Knüfer Jacqueline , Jonigkeit Lorenz , Beleggia Filippo , Holzem Alessandra , Büttner Reinhard , Lohneis Philipp , Meinel Jörn , Ortmann Monika , Persigehl Thorsten , Hallek Michael , Calado Dinis Pedro , Chmielewski Markus , Klein Sebastian , Göthert Joachim R. , Chapuy Bjoern , Zevnik Branko , Wunderlich F. Thomas , von Tresckow Bastian , Jachimowicz Ron D. , Melnick Ari M. , Reinhardt Hans Christian , Knittel Gero
Published: April 2023

Table S3 contains B cell receptor repertoire sequencing data and lists the individual sublcones of the dominant clones of MBC, SMBC and PPMBC lymphomas.
Table S2 from Distinct Genetically Determined Origins of Myd88/BCL2-Driven Aggressive Lymphoma Rationalize Targeted Therapeutic Intervention Strategies
Authors: Flümann Ruth , Hansen Julia , Pelzer Benedikt W. , Nieper Pascal , Lohmann Tim , Kisis Ilmars , Riet Tobias , Kohlhas Viktoria , Nguyen Phuong-Hien , Peifer Martin , Abedpour Nima , Bosco Graziella , Thomas Roman K. , Kochanek Moritz , Knüfer Jacqueline , Jonigkeit Lorenz , Beleggia Filippo , Holzem Alessandra , Büttner Reinhard , Lohneis Philipp , Meinel Jörn , Ortmann Monika , Persigehl Thorsten , Hallek Michael , Calado Dinis Pedro , Chmielewski Markus , Klein Sebastian , Göthert Joachim R. , Chapuy Bjoern , Zevnik Branko , Wunderlich F. Thomas , von Tresckow Bastian , Jachimowicz Ron D. , Melnick Ari M. , Reinhardt Hans Christian , Knittel Gero
Published: April 2023

Table S2 contains a summary of the B cell receptor sequencing data of lymphoma samples. It includes 1) an overview of the investigated samples, 2) a list of characteristics of the dominant clone of each lymphoma sample, 3) a list comparing the frequencies of V family usage in WT samples to the lymphoma frequency, 4) the frequencies of FR and CDR mutations in samples analyzed by full-length BCR sequencing.
Table S2 from Type-I Interferon Signaling Is Essential for Robust Metronomic Chemo-Immunogenic Tumor Regression in Murine Breast Cancer
Authors: Vergato Cameron , Doshi Kshama A. , Roblyer Darren , Waxman David J.
Published: April 2023

Table S2. Results of DAVID analysis showing output of Functional Annotation Clustering for all annotation clusters with an overall cluster enrichment score > 1.3.
Supplementary Methods, Tables S1-S4 from Ribonuclease H2 Subunit A Preserves Genomic Integrity and Promotes Prostate Cancer Progression
Authors: Kimura Naoki , Takayama Ken-ichi , Yamada Yuta , Kume Haruki , Fujimura Tetsuya , Inoue Satoshi
Published: April 2023

Supplementary Table S1. PCR primer sequences for RT-PCR. Supplementary Table S2. Primer sequences for ChIP/DRIP assay. Supplementary Table S3. Relationships of RNASEH2A immunoreactivity (IR) score with clinicopathological findings in prostate cancer (PC) patients. Supplementary Table S4. Univariate and multivariate analysis for recurrence free survival in PC patients.
Table ST1 from Safety, Tolerability, and Pharmacokinetics of TAK-931, a Cell Division Cycle 7 Inhibitor, in Patients with Advanced Solid Tumors: A Phase I First-in-Human Study
Authors: Kuboki Yasutoshi , Shimizu Toshio , Yonemori Kan , Kojima Takashi , Kondo Shunsuke , Koganemaru Shigehiro , Iwasa Satoru , Harano Kenichi , Koyama Takafumi , Lu Vickie , Zhou Xiaofei , Niu Huifeng , Yanai Tomoko , Garcia-Ribas Ignacio , Doi Toshihiko , Yamamoto Noboru
Published: April 2023

Summary of best response to treatment for patients in the pharmacodynamic-evaluable population (schedule A).
Supplementary Table S2 from A Preclinical and Phase Ib Study of Palbociclib plus Nab-Paclitaxel in Patients with Metastatic Adenocarcinoma of the Pancreas
Authors: Hidalgo Manuel , Garcia-Carbonero Rocio , Lim Kian-Huat , Messersmith Wells A. , Garrido-Laguna Ignacio , Borazanci Erkut , Lowy Andrew M. , Medina Rodriguez Laura , Laheru Daniel , Salvador-Barbero Beatriz , Malumbres Marcos , Shields David J. , Grossman Joseph E. , Huang Xin , Tammaro Meggan , Martini Jean-François , Yu Yanke , Kern Kenneth , Macarulla Teresa
Published: April 2023

Treatment-Related Any-Grade AEs (≥10% of Patients Overall).
Figure SF2 from Safety, Tolerability, and Pharmacokinetics of TAK-931, a Cell Division Cycle 7 Inhibitor, in Patients with Advanced Solid Tumors: A Phase I First-in-Human Study
Authors: Kuboki Yasutoshi , Shimizu Toshio , Yonemori Kan , Kojima Takashi , Kondo Shunsuke , Koganemaru Shigehiro , Iwasa Satoru , Harano Kenichi , Koyama Takafumi , Lu Vickie , Zhou Xiaofei , Niu Huifeng , Yanai Tomoko , Garcia-Ribas Ignacio , Doi Toshihiko , Yamamoto Noboru
Published: April 2023

Patient disposition.
Appendix 1 from Under-Representation of Racial Groups in Genomics Studies of Gastroenteropancreatic Neuroendocrine Neoplasms
Authors: Herring Brendon R. , Bonner Andrew , Guenter Rachael E. , Vickers Selwyn , Yates Clayton , Lee Goo , Dhall Deepti , Chen Herbert , Rose J. Bart
Published: April 2023

Structured Queries to PUBMED and EMBASE for Systematic Literature Review of GEP-NEN Genomics Studies.
Supplementary Figure S6 from Tumor Cell–Autonomous SHP2 Contributes to Immune Suppression in Metastatic Breast Cancer
Authors: Chen Hao , Cresswell Gregory M. , Libring Sarah , Ayers Mitchell G. , Miao Jinmin , Zhang Zhong-Yin , Solorio Luis , Ratliff Timothy L. , Wendt Michael K.
Published: April 2023

Depletion of SHP2 in tumor cells delays 4T1 pulmonary metastasis in vivo
Supplementary Figure S4 from Tumor Cell–Autonomous SHP2 Contributes to Immune Suppression in Metastatic Breast Cancer
Authors: Chen Hao , Cresswell Gregory M. , Libring Sarah , Ayers Mitchell G. , Miao Jinmin , Zhang Zhong-Yin , Solorio Luis , Ratliff Timothy L. , Wendt Michael K.
Published: April 2023

Corresponding representative dot plots for the quantification in figure 2B-C and additional T cell exhaustion marker analysis in the study of D2.A1 model.
Supplementary Figure S1 from Tumor Cell–Autonomous SHP2 Contributes to Immune Suppression in Metastatic Breast Cancer
Authors: Chen Hao , Cresswell Gregory M. , Libring Sarah , Ayers Mitchell G. , Miao Jinmin , Zhang Zhong-Yin , Solorio Luis , Ratliff Timothy L. , Wendt Michael K.
Published: April 2023

Combination of SHP099 and α-PD-L1 delays D2.A1 pulmonary growth in vivo
Supplementary Figure FS1 from Circulating Tumor DNA Monitoring Reveals Molecular Progression before Radiologic Progression in a Real-life Cohort of Patients with Advanced Non–small Cell Lung Cancer
Authors: Frank Malene S. , Andersen Christina S.A. , Ahlborn Lise B. , Pallisgaard Niels , Bodtger Uffe , Gehl Julie
Published: April 2023

OS and PFS