bluuebunny/crossref_metadata_2025 huggingface dataset:
Calculation of Standard Costs for Testing to Determine the Agricultural Machinery Performances
Authors:   Rosinformagrotekh, Kuzmin V.N. , Burak P.I. ,   Ministry of Agriculture of Russia, Zolotarev D.E. ,   State Testing Center, Gogolev G.A. ,   State Testing Center, Zhidkov G.A. ,   North Caucasian Machine Test Station, Miroshnikov A.N. ,   North Caucasian Machine Test Station, Horuzhy L.I. ,   Institute of Economics and Management, Postnikova L.V. ,   Russian State Agrarian University Moscow Timiryazev Agricultural Academy
Published: September 2021

It is shown that the procedure for the formation of a government task for the provision of public services (performance of work) in relation to federal government agencies requires the calculation of standard costs for these services (work). The federal list (classifier) of public services (works) of the Ministry of Agriculture of Russia includes the government work titled “Organization and testing of agricultural machinery and equipment to determine their performances”, the results of which are taken into account when providing state support. The data obtained from the results of tests carried out by machine testing stations (MTS) under the jurisdiction of the Ministry of Agriculture of Russia are used. Based on the analysis, the median method for calculating the standard costs has been selected, and the standard method has been selected for individual components. A draft methodology for calculating the standard costs of the government work titled “Organization and testing of agricultural machinery and equipment to determine their performances” taking into account the specifics of its implementation has been developed.
Economic Need to Upgrade Livestock Facilities
Authors:   Institute of Livestock Mechanization, a branch of VIM, Rasskazov A.N. , Mishurov N.P. ,   Rosinformagrotekh
Published: September 2021

The economic and social necessity of the upgrading of livestock facilities based on innovative technology has been substantiated. It is noted that, during upgrading, one should use the technical means recommended by the newly developed System of machines for the animal husbandry industry. The economic efficiency of the upgrading of farms is shown in comparison with the construction of new integrated facilities.
Molecular identification of Bifidobacterium sp. from local yoghurt and evaluation of growth inhibition activity against pathogenic bacteria
Authors: Talukder AP , Haque MN , Mahmud ML , Ekram MAE
Published: September 2021

Yoghurt is a potential source of probiotic bacteria including Bifidobacterium sp. In this context, sour yoghurt sample was collected from local market in Rajshahi for molecular identification and characterization of Bifidobacterium sp. with promising antagonistic activity against pathogenic bacteria. Isolation was done on Luria broth agar media for molecular identification and revealed that isolated bacterium showed 90% similarity with Bifidobacterium sp. Antibiotic sensitivity test result revealed that isolated Bifidobacterium sp. was sensitive to erythromycin, kanamycin, gentamycin, tetracycline, ciprofloxacin, doxycycline out of eleven commercially used antibiotics. Moreover, antagonistic activity of Bifidobacterium sp. was evaluated in our present study against four pathogenic bacteriathrough disc diffusion method. Bifidobacterium sp. had relatively strong antagonistic effect (inhibition zone ≥15 mm) against Salmonella sp. with 16mm and 19mm zones of inhibition at doses of 150 and 200 μg/disc, respectively. Similarly, the isolate showed strong growth inhibitory activity against Acinetobacter sp. and E. coli with inhibition zone of 17 mm and 16 mm at dose of 200 μg/disc while moderate growth inhibitory activity was observed against Aeromonas sp. at applied four doses. Furthermore, present investigation showed that the isolated Bifidobacterium sp. had the utmost effect against Salmonella sp. and exhibited growth inhibition of understudy pathogens in such pattern Salmonella sp.>Acinetobacter sp.> E. coli> Aeromonas sp.
Bangladesh J. Sci. Ind. Res.56(3), 147-154, 2021
Transfer of heavy metals to leafy vegetables in Gazipur textile area
Authors: Begum M , Gani MN , Alam MD
Published: September 2021

Heavy metal pollution of soils is a major concern today because contamination of food chain considered as one of the major environmental pathways of human exposure leading to potential health risk.A pot experiment was carried out to investigate the transfer of Zn, Cu, Ni, Fe, Cd, Cr, Pb and Mn from non-contaminated and contaminated soils to jute leaves vegetable plant and to evaluate their associated health risk in the local population.The mean concentration of the heavy metals in jute leaves vegetable plants followed a decreasing order of Fe>Zn>Mn>Cu>Cr>Pb>Cd>Ni. Among the all heavy metals the highest transfer factor (TF) values was found for Cu (77.50-34.95) and the lowest TF value was observed for Ni(0-0.001) in jute leaves vegetables plant. The daily intake of metals (DIM) for a person through ingestion of jute leaves were in order of Fe>Mn>Zn>Cu>Cr>Pb>Ni>Cd. The values of health risk index (HRI) for the heavy metals were less than 1, therefore, no significant health risk is anticipated for the local consumers through ingestion of jute leaves.
Bangladesh J. Sci. Ind. Res.56(3), 155-164, 2021
Clinicopathological Profile and Outcome of Dengue Fever: A Tertiary Care Hospital Experience
Authors: Rahman Md Anisur , Habiba Begum Most Umme , Md Nizam Uddin Hafez , Monira Serazum , Millat Md Bodrul
Published: September 2021

Introduction: Diverse manifestation of recent dengue outbreak has posed a challenge to pre-existing nature of dengue virus infection and management. This study was designed to observe clinicopathological profile and analyze the diverse presentation and outcome of dengue syndrome in recent outbreak in Bangladesh. Methods: This was a hospital based observational study, carried out in Medicine department of Combined Military Hospital (CMH) Dhaka cantonment in between May and September 2019. Total 300 laboratory-confirmed dengue cases aged more than 11 years presenting within 7 days of symptom onset were studied. Patients who presented 7 days after the onset of symptoms or those who were transferred to other hospitals were excluded from study. Results: Total patients were 300 with male predominance (187, 62.3%) and mean age±SD was 37.6±7.5years with age range 12 to76 years; common presentations were fever (300, 100%),headache (265, 88.3%), skin rash (197, 65.7%), bodyache (186, 62.0%),vomiting (152, 50.7%), diarrhoea (65, 21.7%),abdominal pain (58, 19.3%), and bleeding manifestation (36, 12.0). Eighty four (28%) patient had classical dengue fever (DF), 61 (20.3%) had dengue haemorrhagic fever (DHF), 45(15%) had dengue shock syndrome (DSS) and 110(36.7%) had expanded dengue syndrome(EDS). Relevant investigations showed 157(52.3%) patients had leukopenia,18(6%) had leukocytosis, 254(84.7%) had thrombocytopenia with lowest platelet count 1x109/L,135(45%) had abnormal ALT, 110(36.7%) had abnormal AST, 84(28%) had hyponatraemia,43(14.3%) had AKI,125(41.7%) had pleural effusion with 36(12%) bilateral;102(34%) had ascites, 25(8.3%) developed acalculous cholecystitis;7(2.3%) patient developed cerebrovascular accident. Eighteen (6%) patients required mechanical ventilation and 15 (5%) patients required haemodialysis. Regarding outcome, 5 (1.7%) patients died and 295 (98.3%) patients survived. Conclusion: Dengue fever was presented with common as well as other features and involved a number of organs including liver, kidneys, brain, pleura, peritoneum, and gall bladder and had diverse manifestations and adverse outcome.
J Bangladesh Coll Phys Surg 2021; 39: 213-219
Online-Based Distance Learning During Covid-19 Pandemic at Primary School
Authors: Tenika Illananingtyas
Published: September 2021

The Indonesian government is currently facing a Covid-19 pandemic that is still beyond its control. From print media to electronic media, the mass media continues to report on the number of victims infected with this virus, and the number is declining. One of the predictive steps to prevent the spread of this virus is to maintain social distancing. As a formal educational institution, the school responded quickly to this situation. The school does not hope that by changing the face-to-face learning mode, the virus will spread in its environment. I.e. through distance learning or online learning (online). Therefore, this is the task of the teacher, that is, to be able to create various activities in online learning that can attract students' interest in learning. Especially learning English requires not only theory, but also a lot of practice. Therefore, interactive learning in the form of activities is required to allow students to actively participate in the online learning process. This research aims to obtain important information about the effectiveness of online distance learning (PJJ) for primary schools in Kediri City. The research methods used descriptive qualitative methods to 20 respondents. According to the analysis data, the research results show that online distance learning for elementary schools is considered to be quite effective.
EXPERT EVALUATION OF MEDICAL CARE IN MASS RESPIRATORY AND ORAL INFECTIONS
Authors: Barinov E. Kh. , Muzykin M. I. , Iordanishvili A. K. , Sukhareva M. A.
Published: September 2021

Introduction: An increase in the number of citizens' appeals with claims to the courts regarding inadequate medical care warrants more research on this topic in Russia. Aim: To provide expert assessment of unfavorable outcomes in mass respiratory and oral infections and to develop an algorithm for forensic medical examinations. Methods: We used the data on 120 complex forensic medical examinations related to cases of inappropriate provision of medical care to people with acute respiratory diseases, acute bronchitis, acute pneumonia and acute infectious diseases of the oral mucosa (gingivostomatitis). We studied the errors and defects in the provision of medical care resulting in unfavorable outcomes. Results: We found that the recommended standards for diagnostics and treatment of the studied diseases were fulfilled in only 20.5 % and 23.9 % of cases, respectively, in infectious diseases of the respiratory system. The same time in 100 % of cases of the studied oral infections the standards were not fulfilled. Moreover, we present in details the reasons for the failure to fulfil the standards. Conclusions: We revealed the factors associated with violations of therapeutic, diagnostic and preventive routines and proposed an algorithm for conducting forensic medical examinations in cases of acute respiratory and oral infections.
Teaching with Compassion: Autoethnographies from the front lines of e-learning
Authors: Carozza Linda , Gennaro Steve
Published: September 2021

In 2020 the landscape of teaching in higher education was forced to change given a global pandemic. As a result there were/are inevitable shifts in how course instructors develop and deliver their courses, as well as how they connect with students. Remote, or distance, learning is not a new phenomenon, and e-learning has been delivered across different institutions of higher education for approximately twenty years. However, scholarship in distance learning is dated and the empirical literature in digital pedagogy has gaps when it comes to best practices for teaching and learning in an online format. This paper highlights the importance of teaching with compassion as it fosters better relationships between instructors and students and helps to build community in learning environments. Relationships facilitate learning, and this is especially important in strained times - such as a higher concentration of online teaching and learning due to a pandemic. The notion of compassionate teaching is described. Using self ethnography and drawing on examples from their own course experiences, the authors present what has worked well in delivering small and large courses online. In particular, the first half of the paper focuses on backward course design, multimedia, accessibility, and forward/backward extensions. The latter half of the paper describes strategies embedded in a course and their positive effects for instructors and learners.
Classroom Instructional-Based Technology as Predictor of Quality Services Delivery for Academic Staff in Delta State University
Authors: Omemu Felix , A. Veronic Ajuebon
Published: September 2021

The study investigated the predictive powers of classroom instructional-based technology on quality services delivery of academic staff in Delta State University. Three research questions and three hypotheses guided the study. The study adopted a correlation research design. The population was 861 lecturers in the Delta state university with a sample size of 430 drawn through proportionate stratified method representing 50% of the population. A 30-item Classroom Instructional-Based Technology Scale (CIBTS) and 15-item Quality Services Delivery Scale (QSDS) were used for data collection. The scales were validated by three experts in Information and Communication Units. The internal consistency reliability coefficients of 0.78 and 0.81 were computed for CIBTS and QSDS through Cronbach alpha. Liner regression was used to answer the research questions while t-test associated with linear regression was used to test the null hypotheses at 0.05 level of significance level. It was found that classroom instructional-based technology can significantly predict quality services delivery of academic staff in Delta State Universities. More so, classroom instructional-based technology with the use of interactive whiteboard, video conferencing and virtual field trip can independently predict quality instructional delivery. It was recommended among others that the university authority should ensure that the lecture halls and classrooms in the university are equipped with functional interactive whiteboards. The academic staff should be availed the opportunity for capacity development and enhancement on the use of communication technologies such as interactive whiteboard. The university authorities as well as the heads of departments and deans of faculties should make available computers, projectors, internet connectivity, power supply, printers and flash drive that can encourage video conferencing. The academic staff should be very proactive in the determination of sites that can provide them needed information and learning through the virtual field trip platform.
Worldwide national intervention of developmental screening programs in infant and early childhood
Authors: Kim Seunghyo
Published: September 2021

The prevalence of developmental disabilities is increasing worldwide over time. Developmental issues in infancy or early childhood may cause learning difficulties or behavioral problem in school age, further adversely affecting adolescent quality of life, which finally lead to low socioeconomic status in family, increase in medical expenses, and other relevant issues in various ways. Early childhood has brain plasticity, which means there is high chance of recovering from developmental issues by early detection and timely intervention. Pediatricians are placed an ideal position to meet with young children till 6 years of age, of which age range is the time applicable to early intervention. Determining child’s developmental status can be made by 2 pathways such as developmental surveillance and developmental screening tests. For better results, pediatricians should update their knowledge about developmental issues, risk factors, screening techniques through varying educational program or other relevant educating materials. This paper will update reports on the prevalence of developmental disabilities and review the recent results of Korean developmental screening test and discuss relevant issues. Finally, it will be addressed the pediatrician’s role in early detecting developmental issues and timely intervention.
The Effect of Product Quality and Price Policy On Consumer Loyalty Through the Variables of Customer Satisfaction Ulamm Pt. Permodalan Nasional Madani (Persero) Bekasi Branch
Authors: Zahra Aisya Cindyta , Suharto Suharto , Subagja Dr. Iwan Kurniawan
Published: September 2021

This study aims to determine the effect of product quality on consumer loyalty, the effect of price policy on consumer loyalty, the influence of consumer satisfaction on consumer loyalty, the influence of product quality on customer satisfaction, the influence of price policy on consumer satisfaction, the influence of product quality on consumer loyalty through the variable customer satisfaction, and knowing the effect of price policy on consumer loyalty through customer satisfaction variables. This research was conducted at Pt. Permodalan Nasional Madani (Persero) Bekasi branch involving 98 consumers of the company. Data analysis used path analysis with partial least square (PLS) model with t-test.
Based on data analysis, it is found that product quality has a significant effect on consumer loyalty. The analysis in this path is the effect of product quality on consumer loyalty. Price policy has a significant effect on consumer loyalty.
Satisfaction has a significant effect on consumer loyalty. The analysis in this path is the effect of customer satisfaction on customer loyalty. Product quality has a significant effect on satisfaction. The analysis in this pathway is the effect of product quality on customer satisfaction. Price policy has a significant effect on satisfaction. Analysis in this pathway is the effect of price policy on customer satisfaction.
The consumer satisfaction variable is not a moderating variable. The analysis on this path is the effect of product quality on consumer loyalty through customer satisfaction. The consumer satisfaction variable is not a moderating variable. The analysis in this path is the effect of price policy on consumer loyalty through customer satisfaction.
An Afterlife of a Scholarly Epic: Frazer's Golden Bough and Lewis's Argument from Myth
Authors: Gassman Mattias
Published: September 2021

C.S. Lewis believed that Jesus Christ embodied, in historical fact, a mythic pattern of dying and rising exemplified by deities such as Balder and Osiris. Taken from James Frazer's Golden Bough, an enormously influential work of early anthropological scholarship, the idea of a generalized ‘dying and rising’ motif is now substantially outmoded. Resting specifically on the resemblance between that motif and the story of Christ, and not (unlike Tolkien's argument from myth) on the gospel's general qualities as a story, Lewis's argument from myth thus presupposes an incorrect vision of actual ancient pagan religion. That shortcoming is not fatal, however. In contrast to Chesterton in The Everlasting Man (another formative influence), Lewis used an aesthetic or ideal, rather than a historical, conception of myth, which he carefully distinguished from the word's ordinary senses. Although Lewis did believe that ancient myth-makers worshipped ‘dying and rising’ gods, the core of his case is ‘our’ apprehension of a mythic quality in such stories and the Gospels, independent of the beliefs of ancient writers or hearers of myths. That conclusion should discourage overly sanguine appropriations of Lewis's arguments, which never developed into a general theory of mythology and, once the historicity of the ‘dying and rising’ motif is set aside, can be developed into a case much like Tolkien's.
How Dorothy L. Sayers Helped the Prime Minister of Canada Rally His Country before D-Day
Authors: Revington Robert
Published: September 2021

In May 1944, Dorothy L. Sayers exchanged letters and had a phone conversation with William Lyon Mackenzie King, the prime minister of Canada. Sayers's letter made such an impression on King that he saw mystical and prophetic significance in its arrival and used it in a speech he gave in the Canadian House of Commons. This study uses the digitised archives of King's diaries and the parliamentary records of his speech, as well as Canadian media accounts from the time. It will be shown that Sayers played an underappreciated role in helping the Canadian prime minister rally his country during the war, as the speech that used her letter met with acclaim across the political spectrum and received positive notice in Canadian newspapers. In the weeks leading up to D-Day, Sayers played an integral role in building up the morale of Canada's prime minister, as he endeavoured to inspire his country. Finally, King's diaries offer first-hand testimony of how one important contemporary figure reacted to the radio broadcasts of The Man Born to Be King, as he particularly enjoyed Sayers's portrayal of the masculinity of Jesus.
Küçük Yaşta Ölen Çocukların Anne Babalarına Şefaatlerini Konu Edinen Müellifi Meçhul Bir Manzûme
Authors: ÇAKIN Mehmet Burak
Published: September 2021

Eski Anadolu Türkçesi devrinde yazılan eserlerin büyük bir kısmı, dinî ve ahlakî bir muhtevaya sahip olup muhataplarına yol göstermeyi amaçlamaktadır. Bu bağlamda, Hz. Peygamber’in hadislerini konu alan birçok eser verildiği bilinmektedir. Bu çalışmada Hz. Peygamber’in “büluğ çağına ermeden ölen çocukların anne-babalarına şefaati” hakkındaki hadislerini anlam bakımından ele alan ve müellifi bilinmeyen bir manzûme incelenmiştir. Dil ve imla özelliklerinden Eski Anadolu Türkçesi devrine ait olduğu anlaşılan manzûmede Hz. Peygamber’in hadislerinden yola çıkılarak, küçük yaşta ölen çocukların ahirette anne ve babalarına ne şekilde şefaat edecekleri ve cehennem azabından kurtulmalarına nasıl vesile olacakları canlı tasvirlerle anlatılmıştır. Manzûme, Milli Kütüphane Yazmalar Koleksiyonu’unda 06 Mil Yz A 9084/6 demirbaş numarası ile kayıtlı olan kitapta yer almaktadır.
New EU requirements for road infrastructure development
Authors:   State Enterprise “State Road Transport Research Institute”, Novikova Alla , Sabanska Olga ,   National Transport University, Gerasimenko Alla ,   National Transport University
Published: September 2021

The current situation is considered on the development of safe and secure parking areas for trucks in Europe. The reports of the International Road Transport Union were analyzed on the European Union-funded project on Safe and secure truck parking areas for trucks in Europe and a final report on the study of safe and secure places for truck parking in the EU. The analysis of European regulations is carried out on road infrastructure safety management, specification of truck parking zones, rules of working time and rest of the driver, as well as Ukrainian legislation on these issues. Recommendations for possible measures to improve the legislation of Ukraine are provided in terms of establishing the SSTPA in view of the EU-Ukraine Association Agreement.
Assessment of physical and mechanical indicators of sandy soils by static and dynamic probing data
Authors:   M.P. Shulgin State Road Research Institute State Enterprise – DerzhdorNDI SE, Lytvynenko Anatoаlii , Alieksieienko Oleksandr ,   National Transport University
Published: September 2021

In the work, on the basis of the analysis of tabular data of both current and former normative documents on engineering-geological surveying and design of soil bases and foundations of structures and literary sources, as well as own experience, a graphical and analytical interpretation of determination of the basic values of physical-mechanical normative and calculated indices of sandy soils according to the indicators of static q, MPa and dynamic RD, MPa probing are given. The use of the proposed empirical analytical dependencies can significantly accelerate the processing of field engineering-geological surveying and provide more objective comparison of such soils condition at different objects while making design decisions. They can also be used in the development of resident software, in case of its development and manufacture for automatically calculating the values of the physical and mechanical parameters of sandy soils. The obtained analytical dependencies are presented in the form of two tables for different types of sandy soils: separately for surveying that are carried out using both static and dynamic probes. And the graphs allow you to visually compare these dependencies, that can provide new material for further scientific generalizations and conclusions in the field of soil science and mechanics.
Desain Sensor Tingkat Kekeruhan Air Menggunakan Bahan Fiber Optik
Authors: Masitoh Silviana Dewi , Isnomo Yoyok Heru Prasetyo , Mustafa Lis Diana
Published: September 2021

Pentingnya mengetahui tingkat kekeruhan air terutama dalam aktivitas penggunaan air konsumsi yang berupa air bersih menuntut adanya suatu alat yang digunakan untuk mengukur tingkat kekeruhan air. Pemanfaatan serat optik untuk mengetahui tingkat kekeruhan air dari nilai rugi daya diharapkan dapat menjadi suatu solusi untuk mengetahui tingkat kekeruhan air sebelum digunakan. Penelitian dilakukan dengan mengukur nilai loss daya pada dua ujung serat optik singlemode dan multimode yang dihubungkan dengan fiber coupler, kemudian diukur menggunakan Handheld Light Source dan Optical Power Meter. Fiber coupler dimodifikasi dengan memberi lubang sebesar 1mm pada titik tengah untuk melewatkan air yang diuji. Pengukuran dilakukan dengan kondisi dua ujung optik tanpa jarak, ujung optik diberi jarak sebesar 1mm, ujung optik diberi jarak sebesar 1mm melalui air jernih dan air dengan zat pengeruh berupa tinta. Didapatkan hasil loss pengukuran terbesar pada serat optik singlemode dengan pengeruh warna yellow sebesar 1.9dB. Pada serat optik multimode pengeruh warna yellow sebesar 2.81dB. Hasil grafik dan perhitungan loss daya menggunakan matlab menunjukkan adanya pengaruh penambahan zat pengeruh tinta terhadap daya terukur di OPM. Berdasarkan hasil pengukuran perubahan loss daya tidak konstan pada setiap penambahan 5ml zat pengeruh, dapat dikatakan sensor yang di desain memiliki sensitivitas rendah.
Nilai Tri Kaya Parisudha Sebagai Fondasi Kepatuhan Pajak Orang Pribadi
Authors: I Nyoman Darmayasa  , Ni Kadek Meri Tiar Dwi Absari  , I Nyoman Mandia
Published: September 2021

This study aims to internalize the value of Tri Kaya Parisudha on tax compliance model. Method used was qualitative interpretive through in-depth interviews. The research results in the internalization of Tri Kaya Parisudha values which are rooted in the daily life of the community as the foundation for the practice of fulfilling the tax obligations of individual taxpayers. This tax compliance behavior is a proposed model for the tax compliance of individual taxpayers. The novelty of the research is a model of locality values as the foundation of compliance. This research contributes to the tax authority as a basis for developing policies towards better taxpayers’ compliance.
 
Abstrak
Penelitian ini bertujuan untuk menginternalisasikan nilai Tri Kaya Parisudha pada model kepatuhan pajak. Metode yang digunakan adalah kualitatif interpretif melalui wawancara mendalam. Hasil penelitian berupa internalisasi nilai Tri Kaya Parisudha yang mengakar dalam keseharian masyarakat menjadi fondasi praktik pemenuhan kewajiban perpajakan wajib pajak orang pribadi. Perilaku pemenuhan kewajiban pajak ini menjadi usulan model kepatuhan pajak wajib pajak orang pribadi. Kebaruan penelitian terletak pada penggunaan nilai lokalitas sebagai fondasi kepatuhan pajak. Penelitian ini berkontribusi untuk menjadi pijakan otoritas pajak dalam menyusun kebijakan menuju kepatuhan wajib pajak yang lebih baik.
Melihat Perspektif Kinerja dengan Value for Money
Authors: Silfyana Cahya Manggar Mahdita  , Ikhsan Budi Riharjo  , Lilis Ardini
Published: September 2021

The purpose is to understand and identify concept of performance appraisal using value for money perspective method. This method is carried out with an approach with an interpretive paradigm. The results UPTD Tugu Pahlawan, Balai Pemuda and THR running effectively, efficiently and economically. 3 keys that are applied by UPTD in maintaining the level of Value for Money in their activities, namely collaboration, evaluation and innovation. Good collaboration internal and external organizations will be able to increase effectiveness. Evaluation performance make employees improve and make new innovations to increase revenue and save expenses.
 
Abstrak
Tujuan penelitian ini adalah memahami dan mengidentifikasi konsep penilaian kinerja instansi yang menggunakan metode perspektif value for money. Metode ini dilakukan dengan pendekatan kualitatif dengan paradigma interpretatif. Hasil menunjukkan organisasi berjalan secara efektif, efisien dan ekonomis. Terdapat 3 kunci yang diterapkan UPTD dalam menjaga tingkat Value for Money kegiatan mereka yaitu kerjasama, evaluasi dan inovasi. Kerjasama yang baik di internal eksternal organisasi akan meningkatkan efektivitas. Evaluasi kinerja membuat pegawai berbenah dan melakukan inovasi baru untuk meningkatkan pendapatan dan menghemat pengeluaran. Dengan melakukan hal tersebut akan diraih good corporate governance.
Pentingkah Remunerasi dalam Memediasi Gaya Kepemimpinan Transformasional terhadap Keterlibatan Kerja?
Authors: Fullchis Nurtjahjani  , Ane Fany Novitasari
Published: September 2021

The purpose of this study was to analyze the role of remuneration as a moderating variable for the effect of transformational leadership on job involvement. This research is a quantitative study using Structural Equation Modeling (SEM) analysis tools. The results showed that transformational leadership had no significant effect on worker involvement. High work involvement of lecturers could occur both for lecturers in work environments with leaders who often or rarely apply transformational leadership. Remuneration does not mediate the effect of transformational leadership on work involvement, because the remuneration for lecturers at the institution has not met expectations.

Abstrak

Tujuan dari penelitian ini adalah menganalisis peran remunerasi sebagai variabel moderasi untuk pengaruh kepemimpinan transformasional terhadap keterlibatan kerja. Penelitian ini merupakan penelitian kuantitatif menggunakan alat analisis Structural Equation Modelling (SEM). Hasil penelitian menunjukkan bahwa kepemimpinan transformasional berpengaruh tidak signifikan terhadap keterlibatan kerja. Tingginya keterlibatan kerja dosen bisa terjadi baik pada dosen di lingkungan kerja dengan pimpinan yang sering atau jarang menerapkan kepemimpinan transformasional. Remunerasi tidak memediasi pengaruh kepemimpinan transformasional terhadap keterlibatan kerja karena pemberian remunerasi dosen di institusi belum memenuhi harapan
Manajemen Kas Pemerintah: Implementasi Kartu Kredit Pemerintah dalam Pembayaran Belanja Negara
Authors: Agus Sunarya Sulaeman  , Rizky Ridho Dwinanda
Published: September 2021

The purpose of this study was to examine the benefits of using the Kartu Kredit Pemerintah (KKP) on government cash management. Survey methods and regression analysis techniques with panel data were used in this study. The results of the study proved that the expenditure realization using the KKP did not have a significant effect on idle cash from the use of Uang Persediaan (UP), but the expenditure realization through UP cash did. Operational costs, number of work units and size of Ministry had a significant effect on increasing the value of UP KKP. The use of KKP is recommended for all types of government transactions, and it is mandatory for all spending units. The elimination of payment through cash UP is considered to help the effectiveness of government cash management.

Abstrak

Penelitian ini bertujuan menguji manfaat penggunaan Kartu Kredit Pemerintah (KKP) terhadap manajemen kas pemerintah. Penelitian ini menggunakan metode survei dan teknis analisis regresi dengan data panel. Hasil penelitian membuktikan bahwa realisasi belanja menggunakan KKP tidak berpengaruh signifikan terhadap kas menganggur dari penggunaan uang persediaan (UP), tetapi realisasi belanja melalui UP tunai berpengaruh. Biaya operasional, jumlah satuan kerja dan ukuran Kementerian Negara/Lembaga berpengaruh signifikan meningkatkan nilai UP KKP. Penggunaan KKP disarankan untuk seluruh jenis transaksi pemerintah, dan diwajibkan terhadap seluruh satker. Penghapusan pembayaran melalui UP tunai dinilai membantu efektivitas manajemen kas pemerintah.
Molecular characterization of foodborne pathogenic bacteria recovered from fermented meat products
Authors: Yousef Naeima M. H. , Abd El- Aziz Doaa M. , Mansour Martina A.
Published: September 2021

Foodborne pathogenic bacteria are causing diseases with a significant effect on human health and the economy. The four most common bacterial foodborne pathogens were isolated from different fermented meat products and characterized molecularly in the current study. A total of 20 random samples of fermented meat products, including Hotdog, pepperoni, salami, sausage, and luncheon (4 from each), were collected from different markets to be examined bacteriologically for detection of foodborne pathogenic bacteria. The samples were tested by culture for the presence of bacteria. PCR was used as a diagnostic tool for the proper identification of foodborne pathogenic bacteria. So, the pure isolates were identified and confirmed by PCR- based method using specific primers for each genus. The isolated pathogenic bacteria were identified as Escherichia coli 0157:H7, Listeria monocytogenes, Salmonella sp. and Staphylococcus aureus. Out of 20 samples, only one sample contains E. coli 0157:H7. Listeria monocytogenes and Salmonella spp. were isolated from two samples. At the same time, S. aureus was found in 6 samples, one of which was mecA positive. The results revealed the presence of foodborne pathogenic bacteria in fermented meat samples. So, to decrease the human hazard risk and a major public health threat associated with foodborne pathogenic bacteria and their toxins, a greater emphasis should be applied in control and prevention of contamination during processing and manipulation.
Towards in silico Models of the Inflammatory Response in Bone Fracture Healing
Authors: Lafuente-Gracia Laura , Borgiani Edoardo , Nasello Gabriele , Geris Liesbet
Published: September 2021

In silico modeling is a powerful strategy to investigate the biological events occurring at tissue, cellular and subcellular level during bone fracture healing. However, most current models do not consider the impact of the inflammatory response on the later stages of bone repair. Indeed, as initiator of the healing process, this early phase can alter the regenerative outcome: if the inflammatory response is too strongly down- or upregulated, the fracture can result in a non-union. This review covers the fundamental information on fracture healing, in silico modeling and experimental validation. It starts with a description of the biology of fracture healing, paying particular attention to the inflammatory phase and its cellular and subcellular components. We then discuss the current state-of-the-art regarding in silico models of the immune response in different tissues as well as the bone regeneration process at the later stages of fracture healing. Combining the aforementioned biological and computational state-of-the-art, continuous, discrete and hybrid modeling technologies are discussed in light of their suitability to capture adequately the multiscale course of the inflammatory phase and its overall role in the healing outcome. Both in the establishment of models as in their validation step, experimental data is required. Hence, this review provides an overview of the different in vitro and in vivo set-ups that can be used to quantify cell- and tissue-scale properties and provide necessary input for model credibility assessment. In conclusion, this review aims to provide hands-on guidance for scientists interested in building in silico models as an additional tool to investigate the critical role of the inflammatory phase in bone regeneration.
Hofmeister Effect in RT-QuIC Seeding Activity of Chronic Wasting Disease Prions
Authors: Hwang Soyoun , Beckley Danielle , Alekseev Konstantin P. , Nicholson Eric M.
Published: September 2021

Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) that causes a fatal neurodegenerative disease in cervids. Cases of CWD are rapidly increasing in North America among wild and farmed cervid populations, and potential for zoonotic transmission is not yet determined. Therefore, in order to manage the disease, it is imperative to devise a system that can detect CWD during its early phases to prevent spread to new captive herds through introduction of CWD-affected animals into otherwise CWD-free herds. Real-time quaking–induced conversion (RT-QuIC) assays have been applied to detect the presence of disease-associated prions from various samples in both animals and humans. In this study, we have tested the use of five Hofmeister anions that range from weakly hydrating to strongly hydrating: Na3citrate, Na2SO4, NaCl, NaI, and NaClO4 in RT-QuIC reactions for CWD seeding activity using different recombinant prion proteins as substrates. This work shows how the ionic environment of the RT-QuIC reaction can enhance or diminish the seeding activity. The use of Na2SO4 or NaI as the sodium salt for RT-QuIC using bank vole recombinant prion substrate for the detection of CWD using brain samples reduces the lag time to detect with reasonable specificity. For detection of the CWD in fecal samples, only NaI showed comparable reduction in lag time relative to NaCl but required reduced temperature to alleviate spontaneous fibril formation in negative control samples. Selection of the proper ion environment and recombinant prion protein substrate will make RT-QuIC a powerful diagnostic tool for early detection of CWD prions, further supporting CWD surveillance in wild and captive cervids.
Walkability and Its Relationships With Health, Sustainability, and Livability: Elements of Physical Environment and Evaluation Frameworks
Authors: Baobeid Abdulla , Koç Muammer , Al-Ghamdi Sami G.
Published: September 2021

Urban sprawl and increasing population density in urban centers create the challenge to finding ways of sustainable transportation solutions that preserve the convenience of residents while reducing emissions. Therefore, walkability is a core urban design element because of being advantageous onto three fronts: health, livability, and sustainability. Adopting walkability as urban solution relieves conceptual and practical tensions between the individualistic interests manifested in the desire to own and use private cars, and the need to reduce transportation-based consumption. This review advocates that long-term health benefits from walking and physical activity are the premier incentive to repurpose our cities to be more sustainable and more walking friendly, and spark behavioral change into reducing car dependency for all daily transportations. The review inspects physical elements of the built environment that make the walking trip feasible and desirable, such as connectivity, accessibility, and closeness of destination points, presence of greenness and parks, commercial retail, and proximity to transit hubs and stations. Hence, this review explores a few popular walkability evaluation indices and frameworks that employ subjective, objective, and/or distinctive methods within variant environmental, cultural, and national context. There is no unified universal standardized walkability theory despite the need for rigorous evaluation tools for policy makers and developers. Furthermore, there is a lack of emphasis on air quality and thermal stress while approaching walkability, despite being important elements in the walking experience. Research opportunities in the field of walkability can leverage location tracking from smart devices and identify the interaction patterns of pedestrians with other transportation modes, especially for those with fundamental movement challenges such as wheelchair users.
Systematic Characterization and Identification of Saikosaponins in Extracts From Bupleurum marginatum var. stenophyllum Using UPLC-PDA-Q/TOF-MS
Authors: Liu Wenxi , Cheng Xianlong , Kang Rong , Wang Yadan , Guo Xiaohan , Jing Wenguang , Wei Feng , Ma Shuangcheng
Published: September 2021

Saikosaponins comprise a large group of chemical components present in the Bupleurum species that have attracted attention in the field of medicine because of their significant biological activities. Due to the high polarity, structural similarity, and the presence of several isomers of this class of components, their structural identification is extremely challenging. In this study, the mass spectrometric fragmentation pathways, UV spectral features, and chromatographic behavior of different types of saikosaponins were investigated using 24 standard substances. Saikosaponins containing carbonyl groups (C=O) in the aglycone produced fragment ions by loss of 30 Da, and in addition, type IV saikosaponins could produce [aglycone−CH2OH−OH−H]− and [aglycone−H2O−H]− fragment ions through neutral losses at positions C16 and C17. The above characteristic ions can be used to identify saikosaponins. More notably, the identification process of saikosaponins was systematically summarized, and using this method, 109 saikosaponins were identified or tentatively characterized from the saikosaponins extract of Bupleurum marginatum var. stenophyllum (BMS) using UPLC-PDA-Q/TOF-MS with both data-dependent acquisition (DDA) and data-independent acquisition (DIA) modes, of which 25 were new compounds and 60 were first discovered from BMS. Further studies revealed that the saikosaponins profiles of BMS, Bupleurum chinense DC (BC), and Bupleurum marginatum Wall. ex DC (BMW) were very similar. This work is of great significance for the basic research of the Bupleurum species and provides strong technical support to solve the resource problems associated with Radix Bupleuri.
The Nasopharynx Swab Test for Coronavirus Disease-2019 Is Mild and Will Not Cause Significant Pain and Anxiety: A Cross-Sectional Study Based on Psychiatrists
Authors: Li Wei , Zhou Han , Guo Qian , Li Guanjun
Published: September 2021

Background

Laboratory viral nucleic acid testing (NAT), such as the nasopharyngeal swab test, is now recommended as the gold standard for the diagnosis of Coronavirus disease-2019 (COVID-19). However, the nasopharyngeal swab testing process may cause some discomfort.

Objective

To investigate the influence of nasopharyngeal swab tests on the anxiety and pain felt by psychiatric medical staff.

Methods

A total of 174 psychiatric medical staff (namely 97 doctors, 68 nurses, and nine administrators) and 27 controls were included in the current study. A self-designed questionnaire was used to collect their general demographic information (age, gender, marriage, occupation, profession, smoking history, alcohol consumption history, tea drinking history, previous history of anxiety and depression) as well as their subjective experience, such as nausea, vomiting, coughing, worry, fear, etc, during nasopharyngeal swab collection. The Numerical Rating Scale (NRS) and the State-Trait Anxiety Inventory (STAI) were used to assess the subjects’ pain and state anxiety, respectively.

Results

There were no statistical differences (p>0.05) in age, marriage, smoking history, a history of anxiety and depression, pain scores, and anxiety scores between different professions and genders. The results of partial correlation analysis (controlled for gender and history of depression or anxiety) indicated that the male gender was negatively correlated with being anxious (r=-0.148, p=0.037) and nervous (r=-0.171 p=0.016), although there was no significant difference in pain and anxiety between men and women. In addition, marriage might help women resist negative emotions.

Conclusions

1) There will be mild discomfort during nucleic acid testing, but not enough to cause pain and anxiety; 2) women are more likely to be anxious and nervous during the nucleic acid testing.
Malignancy Rate of Bethesda Class III Thyroid Nodules Based on the Presence of Chronic Lymphocytic Thyroiditis in Surgical Patients
Authors: Cho Yoon Young , Chung Yun Jae , Kim Hee Sung
Published: September 2021

Background

Hashimoto’s thyroiditis (HT), also known as chronic lymphocytic thyroiditis (CLT), may interfere with the accurate cytological diagnosis of thyroid nodules. Recently, HT has been considered a premalignant condition for thyroid cancer development. The diagnosis of atypia of undetermined significance/follicular lesions of undetermined significance (AUS/FLUS) thyroid nodules is challenging and evidence for the malignancy risk of AUS/FLUS thyroid nodules coexisting with CLT is scarce. Therefore, we assessed the malignancy risk of AUS/FLUS thyroid nodules according to the presence of background CLT.

Methods

This study included 357 surgically resected thyroid nodules with AUS/FLUS cytology. Cases with concomitant malignant nodules were excluded. CLT was defined based on the pathologic report after thyroid surgery.

Results

Among 357 tumors, 130 tumors (36%) were confirmed to have coexisting CLT, and 170 tumors (48%) were determined to be malignant after thyroidectomy. Malignancy rates were similar in both groups (48% in each) regardless of background CLT (62/130 with CLT vs. 108/227 without CLT). In the group with CLT, thyroiditis was more frequent in the final pathology (12% with CLT vs. 1% without CLT, P = 0.003). In multivariate analysis, positive BRAFV600E mutation, highly suspicious sonographic features (K-TIRADS 5), and smaller thyroid nodules were significant factors for thyroid malignancies.

Conclusion

The malignancy rate of thyroid nodules with AUS/FLUS cytology was comparable irrespective of the presence of underlying CLT.
The Impact of Interferon Beta-1b Therapy on Thyroid Function and Autoimmunity Among COVID-19 Survivors
Authors: Lui David Tak Wai , Hung Ivan Fan Ngai , Lee Chi Ho , Lee Alan Chun Hong , Tam Anthony Raymond , Pang Polly , Ho Tip Yin , Cheung Chloe Yu Yan , Fong Carol Ho Yi , Law Chun Yiu , To Kelvin Kai Wang , Lam Ching Wan , Chow Wing Sun , Woo Yu Cho , Lam Karen Siu Ling , Tan Kathryn Choon Beng
Published: September 2021

Background

Some studies have indicated that interferon (IFN) may be valuable in COVID-19. We aimed to evaluate the impact of short-term IFN on incident thyroid dysfunction and autoimmunity among COVID-19 survivors.

Methods

We included consecutive adults without known thyroid disorder admitted to Queen Mary Hospital for COVID-19 from July 2020 to January 2021 who had thyroid function tests (TFTs) and anti-thyroid antibodies measured both on admission and at three months.

Results

226 patients were included (median age 55.0 years; 49.6% men): 135 were IFN-treated. There tended to be more abnormal TFTs upon reassessment in IFN-treated patients (8.1% vs 2.2%, p=0.080). 179 patients (65.4% IFN-treated) had a complete reassessment of anti-thyroid antibodies. There were significant increases in titres of both anti-thyroid peroxidase antibodies (anti-TPO: baseline 29.21 units [IQR: 14.97 – 67.14] vs reassessment 34.30 units [IQR: 18.82 – 94.65], p<0.001) and anti-thyroglobulin antibodies (anti-Tg: baseline 8.23 units [IQR: 5.40 – 18.44] vs reassessment 9.14 units [IQR: 6.83 – 17.17], p=0.001) in the IFN-treated group but not IFN-naïve group. IFN treatment (standardised beta 0.245, p=0.001) was independently associated with changes in anti-TPO titre. Of the 143 patients negative for anti-TPO at baseline, 8 became anti-TPO positive upon reassessment (seven IFN-treated; one IFN-naïve). Incident anti-TPO positivity was more likely to be associated with abnormal TFTs upon reassessment (phi 0.188, p=0.025).

Conclusion

IFN for COVID-19 was associated with modest increases in anti-thyroid antibody titres, and a trend of more incident anti-TPO positivity and abnormal TFTs during convalescence. Our findings suggest that clinicians monitor the thyroid function and anti-thyroid antibodies among IFN-treated COVID-19 survivors, and call for further follow-up studies regarding the clinical significance of these changes.