bluuebunny/crossref_metadata_2025 huggingface dataset:
UJI EFEK PENYEMBUHAN LUKA SEDIAAN GEL EKSTRAK ETANOL DAUN AFRIKA (VERNONIA AMYGDALINA.DEL) PADA MENCIT JANTAN
Authors: Ernawaty Ernawaty , Bintarti Tri , Handayani Maya
Published: April 2021

African leaf (Vernonia amygdalina) is one of the potent plants as antidiabetic, antibacterial,antifungal, analgesic and antioxidant. The aims of this study was to determine the wound healingeffect of ethanolic extract of african leaves gel and obtain an effective formula. It was an experimentalresearch. Injuries were made by cutting the back of mice’s skin with diameter ± 1 cm. Fourty eightmice were divided into 8 groups, one group as control, EEDA 1%, EEDA 3% , EEDA 5%, EEDA 7%,EEDA 9% , Bioplacenton as positif control and base gel group. The observation was done bymeasured the diameter of wound visually. The mice declared cure and marked growth of new skin andhair around the wound. At the end of the test performed histophatological test. This study concludedthe ethanol extract of Africa leaves have wound healing effect in mice and EEDA 9% have woundhealing effect at 15th daya.
FAKTOR-FAKTOR YANG MEMPENGARUHI TINGKAT KECEMASAN PASIEN TB PARU DI RA 3 RSUP HAJI ADAM MALIK MEDAN
Authors: Soep Soep
Published: April 2021

Penyakit TBC sudah di kenal sejak dahulu kala. Penyakit ini di sebabkan oleh kuman /bakterimycobacterium tuberculosis.Kuman ini pada umumnya menyerang paru-paru, seperti kelejarbening,kulit,usus/saluran pencernaan, selaput otak dan sebagainya. Kecemasan adalah respon ataupengalaman yang menyakitkan yang dialami oleh seseorang terhadap berbagai alat-alat dalam yang tundukdibawah jaringan syaraf bebas, seperti jaringan jantung, alat pernafasan, kelenjar-kelenjar peluh, dan lainlain.Faktor-faktor yang mempengaruhi kecemasan pasien dapat berasal dari faktor internal dan eksternal.Faktor internal antara lain berupa usia, jenis kelamin, tingkat pendidikan. Sedangkan faktor eksternal berupaancaman tarhadap integritas biologis dan ancaman terhadap konsep diri. Pengumpulan data di lakukandengan mengunakan kuisioner. Hasil peneltian ini menunjukkan faktor-faktor yang mempengaruhi tingkatkecemasan pasian TB paru di Rumah Sakit Haji Adam Malik Medan berdasarkan usia, Jenis Kelamin,Tingkat Pendidikan. Populasi dalam penelitian ini adalah semua pasien yang ada di RA 3 dengan sampel 37orang. pembahasan hasil penelitin bahwa responden yang menunjukkan kecenderungan memilik tingkatkecemasan, pasien yang berusia 46-50 tahun memiliki tingkat kecemasan sebanyak (35,1%). Respondenyang berjenis kelamin laki-laki memiliki tingkat kecemasan sebanyak (56,8%). Responden yangberpendidikan SMA yang memiliki tingkat kecemasan sebanyak (35,1%).
PENGARUH LATIHAN (ROM) PASIF TERHADAP KEKUATAN OTOT EKSTREMITAS PADA PASIEN STROKE DI RUANG RA4 RSUP H. ADAM MALIK MEDAN TAHUN 2014
Authors: Harahap Zainuddin
Published: April 2021

Stroke merupakan syndrom klinis yang awal timbulnya mendadak, progresif, berupa defisit neurologis fokaldan atau global yang berlangsung 24 jam atau lebih atau langsung menimbulkan kematian, dan semata-matadisebabkan oleh gangguan aliran darah otak non-traumatik. Jenis penelitian ini adalah penelitianeksperimental dengan rancangan one group pretest dan posttest. Penelitian dilakukan pada Ruang Rindu A4RSUP Haji Adam Malik Medan, yang dilaksanakan mulai bulan Desember 2013 sampai dengan Mei 2014dengan populasi 87 orang. Teknik pengambilan sampel dengan cara accidental sampling yaitu pengambilansampel yang dilakukan dengan kebetulan bertemu yang berjumlah 12 responden. Hasil penelitian diketahuibahwa kekuatan otot ekstremitas atas pada pasien stroke non hemoragik sebelum dilakukan latihan Range OfMotion (ROM) pasif memiliki tingkat kekuatan otot yang sangat kecil, kekuatan otot ekstremitas atas padapasien stroke non hemoragik sesudah dilakukan latihan Range Of Motion (ROM) pasif, terjadi perbaikanatau peningkatan. Adanya pengaruh yang signifikan antara sebelum dilakukan latihan Range of Motion(ROM) pasif, terjadi perbaikan atau peningkatan dan adanya pengaruh yang signifikan antara sebelumdilakukan latihan Range Of Motion (ROM) pasif dan setelah tujuh hari pemberian latihan Range Of Motion(ROM) pasif. Hal ini perlu ditingkatkan dengan memberikan latihan lebih lama minimal 4 minggu. Setelahitu, perlu diidentifikasi faktor-faktor apa saja yang mempengaruhi kekuatan otot pasien stroke.
KOMUNIKASI TERAPEUTIK PADA PASIEN PRE OPARATIF EFEKTIF MENURUNKAN TINGKAT KECEMASAN PASIEN
Authors: Batubara Irwan
Published: April 2021

Kecemasan pre operasi merupakan suatu respon antisipasi terhadap suatu pengalaman yang dianggap sebagaisuatu ancaman terhadap perannya dalam hidup, integritas tubuh dan kehidupannya sendiri. Pasien pre operasimengalami kecemasan 77,6%, komunikasi terapeutik signifikan menurunkan tingkat kecemasan pasien preoperasi 65,5% (Sawitri, 2004). Di RSUD Kota Padangsidimpuan umumnya pasien operasi terencanamengalami kecemasan, ada yang menjekaskan karena terpaksa, penundaan jadwal operasi dan komunikasiterapeutik belum dilaksanakan terencana. Untuk mengetahui pengaruh Komunikasi terapeutik terhadappenurunan tingkat kecemasan pasien yang akan menjalani opeasi di RSUD Padangsidimpuan. Quasieksperimen. Rancangan dengan rangkaian one group pre test, post test design. Pre test (sebelum intervensi)dan post test (setelah intervensi). Populasi pasien pre operasi terencana yang dirawat di ruang rawat inapbedah Rumah Sakit Umum Daerah Padangsidimpuan, purposif sampling dari bulan September-Oktober2014 berjumlah 30 responden. Analisis data menggunakan uji t berpasangan (paired t-test) memenuhi syaratuji parametrik. Pengaruh komunikasi terapeutik terhadap penurunan tingkat kecemasan pasien pre operatifdari hasil uji t test untuk data berpasangan antara sebelum dan sesudah intervensi komunikasi terapeutikdiperoleh nilai korelasi = 0,658 dengan nilai probabilitas 0,000 atau jauh dibawah 0,05 hal ini menyatakanbahwa kedua variabel mempunyai korelasi yang sangat erat dan benar benar berhubungan secara nyata. Salahsatu syarat uji t berpasangan adalah kedua variabel saling berkorelasi tinggi. Komunikasi terapeutik padapasien pre oparatif efektif menurunkan tingkat kecemasan pasien. Tim perawatan mempersiapkan psikologispasien pre operatif dengan metode komunikasi terapetik yang terencana
TINGKAT PENGETAHUAN KESEHATAN GIGI DAN MULUT DENGAN PENYULUHAN MENGGUNAKAN MEDIA FLIP CHART DAN BONEKA ANIMASI PADA ANAK KELAS V SD NEGERI 105307 SUKARAYA PANCUR BATU TAHUN 2014
Authors: Simaremare Asnita Bungaria
Published: April 2021

Penyuluhan merupakan suatu penerangan yang menekankan pada objek tertentu dan hasil yangdiharapkan adalah perubahan perilaku individu atau sekelompok orang. Penyuluhan merupakan suatuusaha menyebarluaskan hal-hal yang baru agar masyarakat tertarik melaksanakannya dalamkehidupan mereka. Penelitian ini bertujuan untuk mengetahui perbandingan tingkat pengetahuan anakkelas V SD Negeri 064026 tentang kesehatan gigi dan mulut dengan penyuluhan menggunakan mediaflip chart dan boneka animasi. Jenis penelitiannya adalah deskriptif dengan metode suvei, denganpopulasi anak kelas V yang berjumlah 40 orang. Dari hasil penelitian diperoleh tingkat pengetahuananak sebelum penyuluhan dengan media flip chart yang mendapat kriteria baik 5 responden , kriteriasedang 10 responden dan kriteria buruk 5 responden. Sebelum penyuluhan dengan media bonekaanimasi yang mendapat kriteria baik 6 responden, kriteria sedang 5 responden dan kriteria buruk 9responden. Sesudah penyuluhan dengan media flip chart yang mendapat kriteria baik 11 responden,kriteria sedang 9 responden dan kriteria buruk tidak ada. Sesudah penyuluhan dengan media bonekaanimasi yang mendapat kriteria baik 19 responden, kriteria sedang 1 responden dan kriteria buruktidak ada. Kesimpulan penelitian menunjukkan bahwa penyuluhan dengan menggunakan mediaboneka animasi lebih meningkatkan pengetahuan anak kelas V SD Negeri 064026. Hal inidikarenakan boneka animasi lebih menarik perhatian anak-anak, sehingga pesan dalam penyuluhanlebih dapat dipahami.
HUBUNGAN PENGETAHUAN DAN SIKAP IBU DENGAN CAKUPAN PEMERIKSAAN KEHAMILAN DI KLINIK SURYANI KECAMATAN MEDAN JOHOR TAHUN 2014
Authors: Nurhayati1, Ida , Warda2 Eliza
Published: April 2021

Pemeriksaan kehamilan adalah pengawasan sebelum persalinan terutama ditujukan pada pertumbuhan danperkembangan janin dalam rahim. Tujuan penelitian ialah untuk mengetahui hubungan pengetahuan dansikap ibu dengan cakupan pemeriksaan kehamilan di Klinik Suryani Kecamatan Medan Johor Tahun 2014.Jenis penelitian analitik dengan pendekatan crossectional menggunakan data primer, di Klinik SuryaniKecamatan Medan Johor Tahun 2014. Sebanyak 43 orang dengan menggunakan teknik AccidentalSampling. Hasil penelitian menunjukkan bahwa pengetahuan ibu paling banyak ialah pengetahuan baikyaitu 72,1% dan sebesar 65.1% mempunyai sikap positif. Hasil uji chi square menyatakan bahwa terdapathubungan yang signifikan antara pengetahuan dan sikap ibu dengan cakupan ANC. Disarankan bagi petugaskesehatan di klinik Suryani Kecamatan Medan Johor agar dapat meningkatkan kualitas dan memberikanpenyuluhan kesehatan mengenai cakupan pemeriksaan kehamilan.
RELATIONSHIP REGULATION OF F ARDHU PRAYER WITH STRESS LEVEL OF SEMESTER 8 STUDENTS FACULTY OF MEDICINE MUHAMMADIYAH UNIVERSITY PURWOKERTO
Authors: Azizi Rifaqul , Kusumawinakhyu Titik , Finurina Irma
Published: April 2021

Fardhu prayer is a compulsory activity that can create peace of mind for those who run it. For medical students in semester 8 of FK UMP who are experiencing many exams and personal problems, prayer can help calm and relieve stress. This study aims to determine the relationship between the regularity of fardhu prayer and stress levels in 8th-semester students of the Faculty of Medicine, Muhammadiyah University of Purwokerto. Methods use a correlational analysis research design with a cross-sectional approach. The study was conducted on an entire population of 48 students of the Faculty of Medicine, Muhammadiyah University of Purwokerto. Stress level data were obtained using the DASS test questionnaire, and prayer regularity data were obtained from the fardhu prayer regularity questionnaire. Data analysis with Pearson parametric correlation test. Results show the highest level of stress in students who experienced mild stress, and the results of the regularity of student prayers were found that many students regularly prayed. Based on the Pearson correlation test results, the value of p = 0.0 10 was obtained. There is a significant relationship between the regularity of fardhu prayer and the stress of the 8th-semester students of the Faculty of Medicine, Muhammadiyah University of Purwokerto, class of 2013.
PERBANDINGAN PRAKTIK PEMBIAYAAN TABUNGAN SAFARI KOSPIN JASA SYARIAH BANJARAN TEGAL DENGAN FATWA DSN MUI NO. 02 TAHUN 2000
Authors: Putri Nurul Wulandari , Febriani Dhiya Faras
Published: April 2021

Pada zaman dimana ekonomi yang sedang tidak menentu, perlu sekiranya setiap individu memiliki cadangan dana. Cadangan dana tersebut yang sangat mudah dilakukan oleh masyarakat dapat berbentuk tabungan. Dalam hal Kospin Jasa Syariah Capem Banjaran hadir untuk memberikan produk yang dibutukan oleh masyarakat salah satunya Tabungan Safari yang merupakan tabungan berjangka dengan wisata gratis. Tujuan dari penelitian ini yaiitu untuk mengetahui tingkat kepatuhan pada produk Tabungan Safari Kospin Jasa Syariah Capem Banjaran terhadap Fatwa DSN MUI No. 02/DSN-MUI/IV/2000 tentang Tabunga. Penelitian ini menggunakan metode kualitatif deskriptif. Hasil penelitian ini menunjukkan bahwa praktik pembiayaan Tabungan Safari di Kospin Jasa Syariah Capem Banjaran masih ada beberapa yang tidak sesuai dengan Fatwa DSN MUI. Perbandingan praktik dalam pembiayaan Tabungan Safari telah sesuai dengan Fatwa DSN MUI No.02/DSN-MUI/IV/2000 tentang Tabungan, diantaranya nasabah bertindak sebagai shahibul mal dan bank sebagai mudharib, modal yang diiyatakan Kospin Jasa Syariah harus menjelaskan jumlahnya  dan dalam bentuk tunai bukan piutang, pembagian keuntungan  didapatkan harus dinyatakan dalam bentuk nisbah. Tetapi ada juga beberapa praktik yang tidak sesuai dengan Fatwa DSN MUI seperti bank dapat melakukan berbagai macam usaha  tetapi praktiknya Kospin Jasa Syariah menggunakan dana tersebut sebagai dana outstanding, yang mana seharusnya Kospin Jasa Syariah dapat.Kata Kunci: Tabungan Safari, Kepatuhan Syariah,  DSN MUI
Humanity And Divinity Are The Objects Of Sufi Teachings
Authors:   Doctor Of Philosophical Science (PhD), Docent Of The National Institute Of Fine Art And Design Named After Kamoliddin Bekhzod, Uzbekistan, Djumaniyazova Dilfuza
Published: April 2021

Philosophy, especially Eastern philosophy, has always developed in harmony with religion, religious teachings. It is true that at one-time Imam al-Ghazali in his "Tahafut ul-Falasifa" (“Incoherence of the Philosophers”) opposed philosophers, sharply criticized their sixteen metaphysical and four physical rules, and sought to absolutize the divine will, which, although it gained followers and successes in this respect, cannot eliminate the harmony [1] between philosophy and religion, humanity, and divinity. Perhaps he brought Ibn Rushd into the world of philosophy, and Ibn Rushd became famous for illuminating the relationship between philosophy and religion [2].
External Sources Of The Development Of The Ethnographic System Of Terms And Internal Resources Of Their Education
Authors:   Lecturer, Department Of Metodology Of Russian Language, Ferghana State University, Uzbekistan, Nargiza Xodjaeva , Gimadetdinova Viktoriya ,   Lecturer, Department Of Metodology Of Russian Language, Ferghana State University, Uzbekistan
Published: April 2021

The article considers the specific features of the national language, which record the unique socio-historical experience of a certain national community of people, as well as the principle of nomination as a kind of rule formed as a result of the generalization of motivated features in the "speaking" team
Composition Of Modern Uzbek Stories
Authors:   Doctor Of Philosophy In Philology (PhD), Fergana State University, Fergana, Uzbekistan, Oripova Gulnoza Murodilovna , Tolibova Madinakhon Toyirjon Qizi ,   Master Student, Fergana State University, Fergana, Uzbekistan
Published: April 2021

This article discusses the views on the genre of the story, the essence, functions and significance of its composition. The compositional features of contemporary Uzbek stories, the basic artistic functions in the organization of composition, elements of the composition of a work of art are analyzed on the basis of the stories of Shoyim Butaev.
About The Universality Of Modeling
Authors:   Doctor Of Philosophy In Philology, Senior Lecturer, Fergana State University, Fergana, Uzbekistan, Ganieva Shodiya Azizovna
Published: April 2021

The article discusses modeling, the process of abstraction, symbolization, the introduction of modeling into linguistics, the problems of modeling at the language level, the versatility of modeling.
Lexical And Grammatical Aspects Of The Arabic Female Names In Abdulla Kahhar`S Stories
Authors:   Department of Uzbek language and literature, Karshi Engineering Economics Institute, Uzbekistan, Tursunova Yulduz
Published: April 2021

The article provides insights on Arabic women anthroponomy encountered in the stories of Abdulla Kahhar. Their lexical and grammatical features have been extensively studied.
The Role Of Zoroastrianism In The Formation Of The First Statehood
Authors:   Master's Student Of Termez State University, Uzbekistan, Yuldashov Iskandar
Published: April 2021

In this article, the religion of Zoroastrianism was formed in a certain period of time on the basis of certain procedures. The emergence of religion, its formation on the basis of a special system, will be necessary to gain the trust of the people in society and to strengthen the ideological and political power. According to Democritus and Epicurus, there will be no gods and goddesses in society. Man irrigates his mind with spiritual help only in order to overcome the obstacles that appear in front of him. Faith is central to religion. Without faith, there is no question of religion or its form.
The Teaching Tools Of Physics Course Topics On The Basis Of Interdiscipline Integration
Authors:   Associate Professor Of Bukhara State University, Uzbekistan, Atoeva Mehriniso Farhodovna , Saidova Rano Mehriyevna ,   Senior Lecturers Of Bukhara State University, Uzbekistan, Kamolov Vahobiddin Shavkatovich ,   Senior Lecturers Of Bukhara State University, Uzbekistan, Hikmatov Behzod Amonovich ,   Master’s Student Of Bukhara State University, Uzbekistan
Published: April 2021

The article discusses the use of effective teaching aids in teaching physics. In this regard, the importance of interdisciplinary integration, the main organizational and pedagogical activities based on interdisciplinary relations, is widely covered. The main goal of integration in the article is to create a holistic view of the world around the student, that is, to form a worldview, to explore some possibilities for a high-quality solution to the problems of teaching and educating students, to build a comprehensive learning process.
The History Of National Enlightenment In Turkestan
Authors:   Assistant-Professor At The Department “National Idea, Bases Of Morality And Law Education” Of Andizhan State University, Andizhan Region, Republic Of Uzbekistan, Alimova Nodira Ibragimovna
Published: April 2021

The article shows that on the basis of documents of the National Archives of the Republic of Uzbekistan, national enlightenment in Turkestan has long been developed. It is reported that after the Russian government’s occupation of Turkestan, a policy of restricting madrassahs and schools was implemented. The study also noted that as a result of the restrictive policy, their number has decreased, the number of teachers, tutors, mullahs has decreased, and this situation has caused great damage to the upbringing of young people.
From The History Of National Education In Uzbekistan
Authors:   Researcher Of Andizhan State University, Andizhan Region, Republic Of Uzbekistan, Yunusov Bekhzod Alijon Ugli
Published: April 2021

In the present article the history of national schools and madrasahs during the soviet period in Uzbekistan have been analyzed in details. Besides that reformation of national enlightenment system by Jadids, results of reforms, applying new programs and methods to madrasahs and schools have been investigated with important sources.
Mechanisms Of Creating An Electronic Methodological Set In The Professional Development Programs For The State Language
Authors:   Senior Teacher Science Of The State (Uzbek) Language Of The Regional Center, Retraining And Professional Development Of The Staff Of Public Education Of Tashkent City, Uzbekistan, Supiyeva Bukholida Abduvaliyevna
Published: April 2021

The educational and methodological complex is a complete, self-sufficient set of educational and methodological materials that provide high-quality mastering by students of the content of the discipline, which is part of the main educational program and program of additional professional education in the specialties implemented in the college.The teaching materials are developed by the teaching staff based on the requirements from State educational standards, a curriculum of the academic discipline. The following article looks into the mechanisms of creating n electronic methodological set for professional training programs.
The influence of language-specific and universal factors on acquisition of motion verbs
Authors: Smyder Rebecca , Harrigan Kaitlyn
Published: April 2021

This study explores children’s encoding of novel verbs referring to motion events, and finds influence of both language-specific and universal constraints on meaning. Motion verbs fall into two categories—manner verbs encode how a movement happens (run, swim), and path verbs encode the starting and ending point of a motion (enter, fall). Some languages express path more frequently in the verb (Spanish, Hebrew), and others manner more frequently (English, German). Our study expands on this previous work demonstrating sensitivity to these language-specific distributions, as well as expanding to test environmental factors representing a predictable universal distribution. We find that children are sensitive to both the language-specific factors as well as the universal factors in motion verb acquisition.
Un très heureux grand-père
Authors: Sotty Dominique
Published: April 2021

Un grand-père raconte quelques souvenirs de moments partagés avec ses petits-enfants, et particulièrement celui d’un voyage qu’il vient de faire avec une de ses petites-filles et son compagnon.
Ketamine-induced neurotoxicity in neurodevelopment
Authors: Kalopita Konstantina , Armakolas Athanasios , Philippou Anastassios , Zarros Apostolos , Angelogianni Panagoula
Published: April 2021

Ketamine, a phencyclidine derivative and N-methyl-D-aspartate (NMDA) receptor antagonist, is widely used as an anesthetic, analgesic, and sedative agent in daily pediatric practice. Experimental studies have suggested that early prenatal or postnatal exposure to ketamine can induce neuroapoptosis, and establish neurobehavioral deficits that are evident in adulthood. However, most of the currently available clinical evidence is derived from retrospective and observational clinical studies. We, herein, attempt a brief review of the cellular and molecular mechanisms suggested to mediate ketamine-induced developmental neurotoxicity, utilizing a selected number of recent in vivo experimental evidence.
Comparison of morphine, dexmedetomidine and dexamethasone as an adjuvant to ropivacaine in ultrasound-guided supraclavicular brachial plexus block for postoperative analgesia—a randomized controlled trial
Authors: Venkatraman Rajagopalan , Pushparani Anand , Karthik Krishnamoorthy , Nandhini Prabuvel
Published: April 2021

Background and Aims:

An ideal adjuvant to local anesthetic in a nerve block should prolong the duration of analgesia, and hasten the onset of sensory and motor blockade without significant adverse effects. The aim of this study was to compare morphine, dexmedetomidine, and dexamethasone as an additive to ropivacaine in ultrasound-guided supraclavicular brachial plexus block (SBPB) for postoperative analgesia.

Material and Methods:

In this randomized, double-blinded study, 150 patients undergoing upper extremity surgery were randomly divided into three groups: group A (morphine 5 mg), group B (dexmedetomidine 50 μg), and group C (dexamethasone 8 mg). The additives were added to 30 ml of 0.5% ropivacaine solution and administered in SBPB. The duration of postoperative analgesia, onset of sensory and motor blockade, sedation, and adverse effects were observed. The pain was assessed by visual analog scale (VAS) and sedation by Ramsay sedation score. The duration of postoperative analgesia was taken as time consumed from block completion to administration of rescue analgesia (VAS >3).

Results:

The demographic profile was similar in both groups. The duration of analgesia was significantly longer in dexamethasone (867.2 ± 217.6 min) than morphine (739. 2 ± 162.5 min) and dexmedetomidine (654.2 ± 179.9 min) (P < 0.001). The onset of sensory and motor blockade was quicker with dexmedetomidine than dexamethasone and morphine. Three cases of block failure were reported with morphine. No major adverse effects were reported.

Conclusion:

Dexamethasone is an ideal adjuvant to ropivacaine in brachial plexus block to prolong postoperative analgesia and devoid of adverse effects. Dexmedetomidine has a quicker onset of sensory and motor blockade.
Clinical Appraisal of Corpora Cavernosa Injuries (Penile Fracture)
Authors: Elkhafifi Muftah Hamad , Alaorfi Wael E. Y.
Published: April 2021

Background and Aim:

Penile fracture is a relatively rare urological emergency. The aim of this study was to review the experience with 69 consecutive cases in Benghazi, Libya.

Patients and Methods:

Records of 69 penile fracture cases who presented between January 1997 and December 2018 to Hawari Center for Urology, Benghazi, Libya were retrospectively reviewed. Penile fracture diagnosis was based on classic history and typical physical signs. Surgical exploration was performed for all patients under spinal anesthesia.

Results:

The most common mechanism of penile fracture was self-inflicted forceful bending (manipulation) of erected penis which account for 39 (56.5%) patients, followed by vigorous sexual intercourse in 19 (27.5%) patients, masturbation in five (7.2%) patients, rolling over an erect penis in bed in five (7.2%) patients, and slipping in WC in one (1.5%) patient. Clinical features at presentation include intense pain in 97%, sudden audible popping sound in 87%, rapid de tumescence in 94.2%, followed by development of swelling and ecchymosis in all patients (100%). All patients were treated surgically and no intraoperative or immediate postoperative complications were encountered. During the follow-up period, all patients had normal urinary steam and normal sexual function was experienced by 97.1% of the patients. Five patients (7.2%) had long-term complications: penile hypoesthesia (one patient), painful erection (one patient), penile curvature of <15o on erection (one patient), and mild erectile dysfunction (two patients). Most patients were discharged home on postoperative day 1.

Conclusion:

Penile fracture occurred mainly due to forceful sexual manipulation of erected penis, and diagnosis can be made clinically. Immediate surgical repair is the only option to avoid complications.
THE IMPERATIVE OF ACCOUNTING ETHICS IN THE ADOPTION OF FRAUD PREVENTIVE MEASURES IN NIGERIA
Authors: Ngu Solomon
Published: April 2021

This study examined the imperative of accounting ethics in adopting fraud preventive measures in Nigeria. To achieve this objective, the survey research design was adopted while primary data was sourced through structured questionnaire. Data collected were analyzed using Descriptive statistical tools (tables, frequency distribution and percentages) and Spearman’s Nonparametric Correlation. It was discovered that the effectiveness of other fraud preventive measures depends to a large extent on the level of ethical compliance by accountants. Findings also revealed that compliance with ethical codes is an effective way to prevent fraud. Hence, strict enforcement by relevant professional bodies will increase the compliance level, thereby reducing the incidences of fraud in Nigeria. It was concluded that accounting ethics plays significant role in the adoption of fraud preventive measures in Nigeria. Therefore, it is recommended that organizations should adopt measures that will encourage accountants to discharge their responsibilities in accordance with the requirements of the ethical code without undue influence or pressure from management. Furthermore, accounting bodies should put in place strict monitoring and disciplinary measures that will ensure compliance with ethical principles. This will restore the confidence and reputation of the accounting profession as trustees and watchdogs of the society.
Functional development of preschoolers of 5-6 y.o.: report II. Psychophysiologi-cal aspects of the organism
Authors:   Institute of Developmental Physiology of the Russian Academy of Education, Moscow, Krivolapchuk I.A. , Kesel’ S.A. ,   Grodno State University named after Yanka Kupala, Grodno, Chernova M.B. ,   Institute of Developmental Physiology of the Russian Academy of Education, Moscow, Krivolapchuk I.I. ,   Institute of Developmental Physiology of the Russian Academy of Education, Moscow
Published: April 2021

The paper characterizes the functional development of preschool children at the age of 5-6 years old. To assess the functional development of children of this age group in terms of physiological, behavioral, and subjective indica-tors, a set of rating scales was designed. These scales can be used to determine the level of functional development of preschoolers of the corresponding age and to identify chil-dren at risk (those with suboptimal development).
PROBLEMS OF PROTECTING THE POPULATION FROM EPIDEMIOLOGICAL EMERGENCIES IN THE JOURNALISM OF JADIDISM
Authors: Sagatov Djumadulla
Published: April 2021

Мақолада жадидчилик журналистикасида XX аср бошида Туркистондаги ижтимоий ҳаёт, ўлкада эпидемилогик фавқулодда вазиятларнинг келиб чиқиши сабаблари, аҳоли саломатлиги ва атроф-муҳит муҳофазаси билан боғлиқ муаммолар, ёритилиши тадқиқ қилинган.
ABDURAUF FITRAT - A NATIONAL EDUCATED GROWN WRITERS
Authors: Shohruxbek Olimov , Umarova Dilnoza
Published: April 2021

Абдурауф Абдураҳим ўғли Фитрат ХХ аср ўзбек адабиётининг энг ёрқин шахсларидан бири эди. Зеро адиб, айни пайтда, кучли ёзувчи, тили бурро шоир, синчков адабиётшунос, шижоатли сиёсий фигура, моҳир журналист, лидер жадидчи, қайсар миллиятчи, билимдон диншунос, қомусий олим ҳам эдики, унинг ҳар бир жиҳатини алоҳида тадқиқ ва таҳлил қилиш мумкин. Баъзи мутахассисларнинг фикрига кўра, Фитрат ўзбеклардан чиққан илк профессор эди104. Фитрат ва сафдошлари тарихимизнинг энг мураккаб, тез ўзгарувчан даврида яшаб ижод қилдилар, шу сабаб фикр ва қарашларида баъзан ихтиёрий ва баъзан мажбурий туб бурилишлар рўй берган. Фитрат ижодида ҳам вақти-вақти билан устивор йўналишларнинг ўзгарганини кўриш мумкинки, замоннинг зайли шуни тақозо қилган эди. Хўш, Фитрат ўзи ким эди ва қайси хизматлари учун унинг ижодини ўрганишимиз зарур?
ABOUT THREE TRIPS OF MAHMUDHOJA BEHBUDI
Authors: Isomiddinova Munira
Published: April 2021

Мазкур мақола ХХ аср бошидаги жадидчилик ҳаракатининг намояндаларидан бири бўлган Маҳмудхўжа Беҳбудийнинг уч сафари ҳақида бўлиб, жадидшунос олимлар турли манбаларга таяниб берган маълумотлари тилга олинган. Беҳбудий биринчи марта узоқ сафарга 24 ёшида чиққан, бу сафар муқаддас Ҳаж сафари бўлиб у Кавказ ҳамда Туркия орқали ўтади. Иккинчи маротаба Маҳмудхўжа 1903-1904 йилларда Москва, Петербургга боради, 1906йилда Қозон, Уфа, Нижний Новгородда бўлади. Булар саёҳат эмас, хизмат сафари эди. Учинчи мартасида эса кўп давлатлар оралаб ўтган қизиқ саёҳат қилган. Шубҳасиз, бу сафарлар Беҳбудий ижодида ҳам чуқур из қолдирган ва алалхусус саёҳатшунослик илмига, жумладан туризм журналистикаси илмига ҳам беқиёс ҳисса бўлиб қўшилган.
PENERAPAN BIMBINGAN BERKELANJUTAN UNTUK MENINGKATKAN KOMPETENSI GURU DALAM MENYUSUN RENCANA PELAKSANAAN PEMBELAJARAN (RPP) BERKARAKTER DI SMP NEGERI 1 TAMBELANG, KABUPATEN BEKASI TAHUN PELAJARAN 2019-2020
Authors: SITI FATONAH SITI FATONANH
Published: April 2021

Penelitian ini dilakukan dengan tujuan: (1) memperoleh gambaran penerapan bimbingan berkelanjutan untuk meningkatkan kompetensi guru menyusun RPP berkarakter; (2) melihat partisipasi dan aktivitas guru dalam mengikuti kegiatan bimbingan berkelanjutan untuk meningkatkan kompetensi guru menyusun RPP berkarakter; (3) mengetahui peningkatan kompetensi guru menyusun RPP berkarakter  melalui bimbingan berkelanjutan; (4) melihat respon yang muncul dari guru dalam kegiatan bimbingan berkelanjutan untuk meningkatkan kompetensi guru menyusun RPP berkarakter. Penelitian ini menggunakan metode Penelitian Tindakan Sekolah (PTS).  PTS  dapat diartikan sebagai penelitian tindakan / action research yang dilakukan dengan tujuan untuk memperbaiki kwalitas proses dan prestasi belajar siswa. Subjek dalam penelitian ini adalah guru  di SMP Negeri 1 Tambelang, Kabupaten Bekasi, Jawa Barat,  tahun pelajaran 2019 – 2020, semester ganjil.  Berjumlah 30 orang guru , dengan perincian  jumlah guru laki-laki 13 orang, guru perempuan berjumlah 17 orang. Instrumen penelitian yang dipergunakan dalam penelitian ini meliputi: (1) wawancara; (2) observasi  ; (3) diskusi. Hasil dari penelitian ini yaitu sebagai berikut : (1) Partisipasi dan aktivitas guru dalam mengikuti kegiatan bimbingan berkelanjutan untuk meningkatkan kompetensi guru menyusun RPP berkarakter cukup tinggi dan bersemangat; (2) Melihat respon yang muncul dari guru dalam kegiatan bimbingan berkelanjutan untuk meningkatkan kompetensi guru menyusun RPP berkarakter; (3) Bimbingan berkelanjutan dapat meningkatkan motivasi guru dalam menyusun RPP dengan lengkap. Guru menunjukkan keseriusan dalam memahami dan menyusun RPP apalagi setelah mendapatkan bimbingan pengembangan/penyusunan RPP dari peneliti. Informasi ini peneliti peroleh dari hasil pengamatan pada saat mengadakan wawancara dan bimbingan pengembangan/penyusunan RPP kepada para guru; (3) Bimbingan berkelanjutan dapat meningkatkan kompetensi guru dalam menyusun RPP. Hal itu dapat dibuktikan  dari hasil observasi /pengamatan yang memperlihatkan bahwa terjadi peningkatan kompetensi guru dalam menyusun RPP dari siklus ke siklus. Pada siklus 1 nilai rata-rata komponen RPP 79% dan pada siklus 2 = 93%. Jadi, terjadi peningkatan 14%  dari siklus 1
ANALISIS KINERJA KEUANGAN DENGAN PENDEKATAN METODE ECONOMIC VALUE ADDED (EVA) PADA PT. BLUE BIRD Tbk PERIODE 2014-2018
Authors: Zakaria Hamzah Zeze , Awaliyah Sarah
Published: April 2021

Penelitian ini bertujuan untuk mengetahui kinerja keuangan PT. Blue Bird Tbk yang diteliti berdasarkan analisis dengan menggunakan metode Economic Value Added (EVA) periode 2014 – 2018, jenis yang digunakan dalam penelitian ini adalah kuantitatif. Populasi penelitian yang juga merupakan sampel penelitian ialah laporan keuangan lima tahun terakhir (2014-2018). Pengumpulan data di lakukan dengan mengambil dokumentasi dari website resmi dan selanjutnya dianalisis dengan menggunakan metode EVA yang terdiri dari analisis NOPAT, Invested Capital, WACC, Capital Charges. Hasil penelitian menunjukkan bahwa Economic Value Added (EVA) pada PT. Blue Bird Tbk periode 2014-2018 mendapatkan nilai EVA < 0 artinya perusahaan tidak dapat menciptakan nilai tambah  ekonomis (NITAMI). Di karenakan tingkat biaya modal lebih tinggi dibandingkan dengan tingkat pengembalian laba operasi perusahaan sebab adanya pesaing baru berupa transportasi online.
Therapeutic effect of YSY01 on osteoarthritis in rabbit: involvement of suppressing signaling pathway of NF-kB and MMP-9
Authors: Yang Zhou , Zhan Feng , Lin Shu-dian , Liu Ying , Zhan Yu-wei , Cheng Jiao-mei
Published: April 2021

Introduction

It has been reported that the NF-κB and MMP-9 signaling pathways were involved in the pathogenesis of osteoarthritis (OA), while the treatment of OA by YSY01 could inhibit the proteasome activity. Therefore, we aimed to study the therapeutic effect of YSY01A treatment on OA via interfering with expression of NF-κB and MMP-9.

Material and methods

Western blot analysis and immunohistochemistry (IHC) assays were used to measure the expression of NF-κB and MMP-9 in animal models established via SH treatment or cellular models established via sodium nitroprusside (SNP) treatment. MTT assay and flow cytometry analysis were performed to observe the effect of YSY01 treatment on cell viability and apoptosis.

Results

The decreased expression of NF-κB and MMP-9 was observed in OA rabbits and cells treated by YSY01A, thus indicating the inhibitory effect of YSY01A on NF-κB and MMP-9 expression. And YSY01A exhibited a positive therapeutic effect on OA both in vivo and in vitro by inhibiting the expression of NF-κB and MMP-9. Meanwhile, YSY01A treatment could increase cell viability to a certain degree and decrease the apoptosis index, which suggested the application of YSY01A in OA therapy.

Conclusions

The levels of NF-κB and MMP-9 which were associated with aggravated apoptosis were up-regulated in OA models in vivo and in vitro. YSY01A treatment could down-regulate the expression of NF-κB and MMP-9 and inhibit cell apoptosis, thus reducing the severity of OA.
MiR-125b-5p enclosed in hypoxic HK2 cell-derived extracellular vesicles alleviates renal ischemia-reperfusion injury by regulating NLRC5
Authors: Xu Kai , Zhang Lifeng , Zhang Lei , Zhang Lei , Zhang Ze , Qian Siwei , Zou Xiangyu , Chen Shuqiu , Zuo Li , chen ming , Zhang Guangyuan
Published: April 2021

Introduction

In this study, we validated the changes in microRNA (miRNA) expression in hypoxic human kidney 2 (HK2) cell-derived extracellular vesicles (EVs). Additionally, we investigated the mechanism by which miRNA that are derived from EVs alleviated renal ischemia-reperfusion (I/R) injury.

Material and methods

HK2 cells were treated in a hypoxic chamber (1% O2) for 12 h.EVs were obtained as supernatant from ultracentrifugation and characterized. After examining 16 differentially expressed EV-miRNAs between normoxic and hypoxic conditions by RT-PCR and bioinformatics analysis, miR-125b-5p was selected for further analysis. Normoxic and hypoxic HK2 cells-derived EVs as well as EVs that were isolated from miR-125b-5p negative control (miR-NC)-transfected or miR-125b-5p mimic (miR-MI)-transfected HK2 cells were injected in mice with renal I/R injury. The degree of renal injury was assessed by periodic acid-Schiff staining, renal tubule injury score, and plasma creatinine levels. Bioinformatics analysis was performed to determine the potential target genes of differentially expressed miRNAs. RT-PCR,western blotting, luciferase reporter assay, and immunohistochemistry were performed to investigate the relationship between miR-125b-5p and the NLR family CARD domain containing 5 (NLRC5).

Results

RT-PCR revealed that from 16 differentially expressed miRNAs, four EV-miRNAs were upregulated. Animal study showed that miR-125b-5p overexpression in EVs alleviated renal I/R injury. Bioinformatics analysis predicted that NLRC5 was targeted by miR-125b-5p. Moreover, the relationship between miR-125b-5p and NLRC5 was also validated.

Conclusions

There were several miRNAs that were upregulated (including miR-125b-5p) in hypoxic HK2 cells. Hypoxia induced EVs that alleviate renal IRI, can be attributed to miR-125b-5p for targeting NLRC5.
Metodologias ativas no ensino de administração estratégica: gamificação
Authors: Hampf Lucas Copacheski , Napoli Giovanni , Baniski Gislaine Martinelli
Published: April 2021

O objetivo deste estudo é demonstrar como os jogos eletrônicos (games) estão contribuindo para a formação de competências de pensamento estratégico. O estudo é parte do programa de iniciação científica e foi realizado por meio de pesquisa bibliográfica enfatizando a gamificação no ensino ativo da administração estratégica. Foi realizada uma pesquisa qualitativa adotando-se entrevistas com gamers como meio de coleta de dados. Estes dados foram analisados confrontando-se com a teoria pesquisada, desenvolvendo-se uma comparação entre etapas do jogo e conceitos possíveis de serem aprendidos. O estudo demonstra as competências que podem ser desenvolvidas pelos jogos e sugere que a aproximação e analogia com games de interesse dos estudantes pode ser uma metodologia eficaz no aprendizado de Estratégia.
Política pública de formação para o trabalho: o papel da educação profissional e tecnológica na relação entre educação e geração de renda, à luz da teoria do capital humano
Authors: Graczkowski Jefferson Vinicius , Pereira Adriano Willian da Silva Viana
Published: April 2021

As Políticas Públicas de Formação para o Trabalho iniciam-se em 1909 com o Decreto nº 7.566, do então Presidente da República Nilo Peçanha, que criou 19 "Escolas de Aprendizes Artífices”, sendo este o marco inicial da Educação Profissional e Tecnológica no Brasil (EPT). Após décadas de um modelo dual no sistema educacional brasileiro, onde a EPT era relegada a um sistema educacional de segunda linha, que visava formação de trabalhadores para a indústria, a EPT assume hoje destaque na integração da educação do indivíduo como um todo. Este trabalho trata de uma abordagem de natureza descritiva e exploratória, pois procura através de uma revisão bibliográfica descrever a relação entre a Educação Profissional e Tecnológica e o desenvolvimento, e exploratória através de um estudo de caso nas séries concluintes dos Cursos Técnicos Subsequentes de Eletromecânica, Eletrotécnica, Eventos e Mecânica do IFPR – Curitiba, objetiva encontrar relação entre a Educação e a Geração de Renda. O estudo de caso abordou uma análise quantitativa dos resultados da pesquisa Likert através de método estatístico, Correlação de Pearson e Regressão Linear, verificando-se que 73,7% dos discentes estarem empregados auferindo renda através da educação recebida. Assim a EPT é política pública de geração de trabalho e renda que confirmou os conceitos de Schultz e Becker onde as relações entre o capital humano, fruto da educação, são causa e efeito do crescimento, desenvolvimento econômico e geração de renda.
ANALISIS MANAJEMEN PEMBELAJARAN PENDIDIKAN DINIYAH FORMAL (PDF) TINGKAT ULYA DI DAYAH BABUSSALAM MATANGKULI KABUPATEN ACEH UTARA
Authors: Khaidir Khaidir
Published: April 2021

Tujuan penelitian ini adalah: mendeskripsikan perencanaan, pelaksanaan, dan evaluasi pembelajaran di PDF Babusalam Matangkuli Kabupaten Aceh Utara. Penelitian ini menggunakan jenis penelitian kualitatif. Teknik pengumpulan data terdiri dari wawancara, observasi partisipan dan dokumentasi. Analisis data menggunakan tahapan, reduksi, penyajian data, dan verifikasi data. Hasil penelitian menunjukkan bahwa perencanaan pembelajaran di PDF Babussalam Matangkuli, untuk pembelajaran fiqih tidak ada suatu ketentuan baku rancangan rencana pembelajaran. Pembelajaran pada pelajaran dayah berlangsung seperti biasa, mengaji di dayah seperti umumnya. Pelaksanaan pembelajaran di PDF Babussalam Matangkuli, untuk pembelajaran umum diambil waktu khusus yaitu pagi hari sebelum jadwal mengaji di dayah seperti biasanya. Sedangkan untuk pembelajaran fiqih pembelajarannya mengikuti waktu ngaji sehari-hari di dayah. Evaluasi pembelajaran di PDF Babussalam Matangkuli, hasil pembelajaran baik pelajaran umum dan pendidikan keagamaan Islam, penilaian tidak hanya ditekankan pada aspek kognitifnya tetapi juga pada aspek afektifnya.
PEREMPUAN DAN KONFLIK SOSIAL: SEBUAH UPAYA PENYELESAIAN KONFLIK AGRARIA DI KABUPATEN TAKALAR SULAWESI SELATAN
Authors: Arifin Suryanto , Raf Nuvida , Genda Arsyad , Sultan Sultan
Published: April 2021

Penelitian ini mengungkapan isu konflik sosial dari aspek konflik agraria dan upaya pelibatan perempuan khusunya ibu rumah tangga dalam pengelolaan konflik sosial. Dilaksanakan di Kabupaten Takalar tahun 2016 dan Desa Timbuseng Kecamatan Polongbangkeng Utara Kabupaten Takalar tahun 2018, dengan teknik pengumpulan data wawancara mendalam kepada tokoh kunci yang terlibat dalam konflik sosial dan Focus Group Discussion kepada ibu rumah tangga sebagai agen penyelesaian konflik sosial. Penelitian ini menunjukkan bahwa konflik agraria telah berlangsung cukup lama dengan mengalami eskalasi yang berujung memakan korban jiwa, serangkaian upaya yang dilakukan oleh aparat dengan memediasi kedua belah pihak yang bertikai namun belum memiliki kesepakatan yang berpotensi kembali terjadi konflik sosial. Dengan keterlibatan perempuan sebagai subjek (aktor/pelaku) pada kelembagaan formal dan informal sehingga dapat berkontribusi secara positif melalui pemetaan potensi, permasalahan dan upaya pengelolaan konflik sosial.
TRADISI DETUNUHA: MEDIA PENINGKATAN INTERAKSI SOSIAL PADA MASYARAKAT MUNA DESA BANGKALI KABUPATEN MUNA
Authors: Maliudin Maliuddin , Lestariwati Lestariwati , Suryati Nurmin , Hermin Laode
Published: April 2021

Penelitian ini membahas tentang bagaimana sebuah tradisi dalam masyarakat dapat menjadi sebuah wadah dalam meningkatkan interaksi sosial pada masyarakat Muna desa Bangkali. Hal ini dilakukan karena melihat bahwa desa Bangkali merupakan desa yang termasuk padat penduduknya sehingga perpecahan dan friksi mudah terjadi. Hal ini berpengaruh pada baik buruknya atau kuat dan lemahnya interaksi sosial dalam masyarakat. Salah satu solusi dalam menghindari friksi atau perpecahan tersebut adalah dengan tradisi detunuha. Tradisi detunuha merupakan tradisi membuat makanan tradisional dari ubi, kelapa dan gula merah yang melibatkan orang banyak. Penelitian ini bertujuan untuk mengetahui sejauh mana  tradisi detunuha dapat menjadi media untuk meningkatkan interaksi masyarakat Muna Desa Bangkali, Kabupaten Muna. Hasil yang didapatkan bahwa pada proses tradisi detunuha pada masyarakat desa Bangkali dari awal sampai akhir selalu melibatkan banyak orang. Mereka saling membantu dan saling bekerjasama agar kegiatan dapat berjalan dengan lancar. Dalam bentuk-bentuk interaksi, semua proses yang terjadi masuk ke dalam kategori bentuk coorperation (kerjasama) dan joint—venture (usaha patungan).
Role of GandharvaHasta Tail in Geriatric Constipation - A Case Study
Authors: Khekale Kranti N.
Published: April 2021

Constipation is a common complaint in older adults. Although constipation is not a physiologic consequence of normal aging, decreased mobility and other medical conditions may contribute to its increased prevalence in older adults. The prevalence of constipation rises dramatically with age, with some estimates approaching 50% among adults over 80 years of age. There are a variety of over-the-counter and prescription laxatives available for the treatment of constipation. There are many laxatives sold in the market. They have not been studied in controlled trials to make a recommendation. Its side effect may be harmful to patient. There is no one best evidence-based treatment for chronic constipation in the elderly.
this study, shows single case of geriatric patient suffering from constipation wherein  Gandharvahasta tailwas given 10ml orally. The reference of Gandharvahasta tail is  Bhaishajya Ratanavali. Gandharvahasta tail acts as mild laxative with sweet taste, pleasant smell. Gandharvahasta Tail shows significant result with no side effect. It is easily palatable so there is no compliant for taking medicine.
PSYCHOLOGICAL DISORDERS IN OLD AGE AND AYURVEDA
Authors: Bansode Chitrakala
Published: April 2021

According to modern concept aging is a physical, physiological, psychological phenomenon which is result because of inherent evolutionary changes occurring in the mind and body system. Hypertension, Ischemic Heart Disease, Diabetes, Senile Dementia, Alzheimer's disease, Parkinsonism, Degenerative Arthritis, Osteoporosis, Opportunistic Infections, Prostatic enlargement, degenerative eye diseases like Cataract which causes major morbidity in old age. In old age most commonly Psychological disorders are observed like senile dementia, Alzheimer disease, depression. Ayurveda describe aging is Swabhava of human body i.e. ''Shirayate Tata Shariram''. Ayurveda Samhita described that after sixty age function of brain decrease so psychological disorders are occur in this age. Aim of this subject is to enlighten the basic concept of mental disorder both in Ayurveda and Modern books and discussion on different views. In recent era we see technology increases in health science but life span of people decreases from 100 years to 60- 70 years. Ayurveda is science of life and longevity. Ayurveda give basic knowledge about age related problems. Conclusion made by comparing between Ayurveda and modern concepts of Psychological disorders.
                 Demographically India is the second largest country in the world with the largest number of aged persons (60+ years). Psychological disorders are big problem in old age, so for confirm diagnosis and treatment we need to enhance our knowledge.
Causative factor for premature ageing
Authors: Usgaonkar Praneta
Published: April 2021

Ageing is the change in biology of an organism as it ages after its maturity. Such changes range from those affecting its cells and their function to that of the whole organism. As ageing is the natural process of growing older yet there are many factors that play a role in whether we age gracefully or if we are the one out of people who age faster than our biological. Globally, the population is ageing rapidly But the major concern in the current era is the â€œpremature ageingâ€ and not the natural ageing or what we can call blissful ageing, which can be due to several causative factors such as smoking, drinking, sun, moisture, perpetual anger, diet, excess weight, stress, free radicals etc.
The era that we live in is full of stress due to stressful tasks that line up our way. Chronic stress is one of the most important factor that accelerates aging by shortening DNA telomeres
The modern era has taken great strides in providing materialistic comfort to human beings but along with comfort ailments have come along. Stress is one such by - product of modern day lifestyle. The stress that is left unchecked can contribute to many health problems such as hypertension, heart diseases, obesity and diabetes.
Stress also affects our mind drastically. Chronic stress can lead to mood disorders.