bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengaruh Lingkungan Kerja Terhadap Kinerja Pegawai Pada Dinas Kependudukan Dan Pencatatan Sipil Kabupaten Barito Selatan Tahun 2021
Authors: Kurniaty Harlina
Published: May 2021

Work discipline is an important aspect in generating employee performance which will create a conducive work climate so that it can synergize with increasing employee morale or enthusiasm to achieve a goal. This study aims to see the effect of work influence on employee performance at the Manpower and Transmigration Office of South Barito Regency in 2021.

In this study, the author of quantitative quantitative research. The data used are primary and secondary data collected through, observation, interviews, documentation and questionnaires. The sample used as the object of research was 30 people. This study has two variables, namely the independent (X) Work Discipline and the dependent variable (Y) Employee Performance in the job training and workforce placement sections.

The results obtained in the calculation of simple linear regression are Y = 18,628 + 0.553 x where the value (a) is 18,628; and the coefficient value (b) is 0.553. Then the results of tcount> are obtained from the test that tcount> ttable (3.374 ≥ t table 2.051) then Ho is rejected and Ha is accepted, meaning that there is an effect of work discipline on employee performance at the Manpower and Transmigration Office of South Barito Regency in 2021.

Based on the conclusion, it can be seen that the effect of work discipline on employee performance in the job training section and placement of workers at the Manpower and Transmigration Office of South Barito Regency in 2021 is important because it can improve employee performance in carrying out their duties according to des jobs.
Pelaksanaan Pengadaan Barang/Jasa Secara Elektonik (E-Procurement) Pada Satuan Kerja Pelaksanaan Jalan Nasional Provinsi Kalimantan Tengah
Authors: Juniawan Rooswandy
Published: May 2021

This research aims to analyze the implementation and identify the inhibitory factors of the Implementation of the Procurement of Goods /Services Electonic (e-procurement) in the National Road Implementation Task Force of Central Kalimantan Province. The desired target in the study, the researchers gave a limitation of the problem the implementation of electronic tenders for construction workers (roads/bridges) in the National Road Implementation Task Force of Central Kalimantan Province.

The research approach in this study is a type of qualitative descriptive that aims to describe the complexity and dynamic in the procurement of electronic goods/services. Data collection was conducted through observations, interviews, and documentation. The interviewees were the head of the task force, the commitment-making officer, the task force assistant, the treasurer, and other employees related to the electoral auction in the Central Kalimantan Province National Road Implementing Task Force.

The results of the study show the conclusion that the implementation of procurement of goods /services electronically in the national road implementation taskforce of Central Kalimantan Province has been carried out for the last few years. All stages of the auction are electonic through a long process of 14 stages that all transparent using a system that can be accessed for the public. However, the factor of inhibiting the implementation of electronic procurement of goods /services (e-procurement) in the national road implementation taskforce of Central Kalimantan Province is 1) HR, namely the lack of expertise in running the application of Electronic Procurement System (SPSE) as well as the lack of employees who have a Certificate of Procurement of Service Goods which is an absolute requirement to become Pokja Election / Procurement Officer. 2) Technology, internet network capacity that causes internet access speed to be slow.
Pelatihan Pemanfaatan Spreadsheet untuk Meningkatkan Kompetensi Guru SMK Bisnis dan Manajemen dalam Menyusun Laporan Keuangan
Authors: Helmayunita Nayang , Betavia Ade Elsa , Septiari Dovi , Dwita Sany
Published: May 2021

Based on interviews conducted with the Head of the Vocational High School Management and Business Vocational High School Subject Teacher Conference in West Sumatra Province, it was found that teachers need to improve their competence about the use of Computer Accounting Applications. It is known that teachers still lack competence, and teachers are still unfamiliar with how to operate various menus and functions that can be used in a spreadsheet program to complete company financial reports. Based on this condition, the teaching and learning process for subjects has been done more with the lecture method and a little practice. So that this affects the competence of SMK graduates. In fact, the guidance for the world of work requires SMK graduates to operate this application program properly. The community's activity was carried out for two days on 18 and 19 September 2020 at SMKN 2 Kota Padang. The implementation is carried out in three stages, namely material presentation, integrated training, and evaluation. At the end of the activity, it was known that there was an increase in the understanding of the participants regarding the preparation of financial statements of trading companies using Microsoft Excel with a case settlement value that could be achieved was 85.71%. Furthermore, this increase in teacher competence is expected to be transferred to students and is reflected in the value of UKK and the acceptance of graduates in the world of work.
Berkebun di Rumah pada Masa Pandemi dengan Memanfaatkan Sampah Rumah Tangga
Authors: Santosa Sartono Joko , Siswadi Siswadi , Fajarwanto Andi
Published: May 2021

Food is a basic need for humans that must be fulfilled as a basic need; food has an essential meaning and role in a nation's life. The problems faced during the Covid 19 pandemic have forced everyone to keep quiet and work from home so that everyone tries to take advantage of this free time with productive activities. One of these activities is gardening at home using household waste. To make this happen, from April to September 2020, the community service team conducted counseling and training and practices for the Amuktiwo Ngubo farmer group, Kestalan sub-district, Banjasari District, Surakarta City, Central Java. The results of the program show that the Covid 19 pandemic forces every citizen, especially partner groups, to do activities at home, which results in a lot of free time available, so gardening at home by using household waste as a planting medium is the most appropriate solution because the environment is clean and healthy. The crop yields can meet the needs of the kitchen, which results in reduced expenses. Also, if this program is implemented nationally, the goal of community food security will be achieved.
Program Kemitraan Masyarakat: Perancangan Praktikum Matematika dan IPA Sederhana bagi Guru SMP
Authors: Astiti Kadek Ayu , Ardan Andam S. , Samo Damianus Dao
Published: May 2021

This community service activity improves teacher skills in carrying out simple Mathematics and Natural Sciences practical activities. This activity is designed in the form of training through several stages, namely 1) coordinating with partner schools for implementation time, 2) providing material related to simple mathematics and science practicum, 3) Mentoring for Mathematics and Natural Sciences teachers in designing simple practicums, and 4) program evaluation. Participants in this activity were several Mathematics and Natural Sciences teachers from SMP N 1 Nekamese, SMP N 2 Nekamese, SMP N 4 Nekamese, and SMP N 5 Nekamese. In the training activities, the participants were quite enthusiastic in participating in the activities, which could be seen from the enthusiasm to participate in the activities and dynamic discussions. Based on the final test results, there was an increase in the teacher's ability before and after the training with an n-gain value in the high category.
Pemberdayaan Potensi Diri dalam Kewirausahaan pada Anggota Posyandu Remaja di Kecamatan Bubutan Surabaya
Authors: Sosialita Tiara Diah , Sari Reza Lidia , Nisa Valina Khiarin
Published: May 2021

Based on the need analysis conducted, the problems are Bubutan subdistrict of Surabaya City has a large number of young people, but it is not balanced with productivity. In this stage, adolescents should be directed to carry out positive activities by their interests. Results of the initial assessment found that young people in Bubutan are interested in the field of entrepreneurship. Still, unfortunately, most of them did not have basic entrepreneurial knowledge and skill. The solution that is expected to be effective for those problems is an entrepreneurship education program to empower self-potential in the entrepreneurial field. In fact, the implementation of this program can be a solution to the need of young people in Bubutan, which was lack entrepreneurial education. This program was given to Posyandu Remaja with consideration that they can become initiators for other adolescents to develop productivity, quality, and self-character in the industrial era 4.0, which demands global competition.
Peningkatan Kapasitas Produksi Terasi Rebon di Desa Ketapang, Kotamadya Probolinggo
Authors: Firdaus Muhamad , Intyas Candra Adi , Yahya Yahya
Published: May 2021

Kademangan is a shrimp paste production center in the Probolinggo municipality. The shrimp paste made from this fish processing center is of lower quality than similar products on the market. The varying size of the raw materials is a significant problem in shrimp paste production in this business hub. This activity aimed to improve the quality of the shrimp paste product by introducing and enhancing the partners' skills in using grinders and shrimp powder for rebon shrimp in making rebon shrimp paste. The method of this service activity consists of training, monitoring, and evaluation of the activities. This activity showed that the partners had received training on the production of shrimp paste and its quality and the use of grinding machines and machines for boiling shrimp meal. During the partner monitoring period, it became apparent that the partners had switched the technology from manual production of shrimp paste to machine production. The evaluation results show that the partners are familiar with grinding and grinding machines in making Rebon shrimp paste. The resulting products are of higher quality than those made before the partners used the shrimp grinding shrimp flour machines. The conclusion is that the use of grinding and flour machines for rebon shrimp by partners has increased the production capacity by three times and increased the quality of the rebon shrimp paste.
Edukasi Dampak Covid-19 Melalui Komik serta Pembagian Masker dan Sembako bagi Masyarakat Terdampak Covid-19 di Kelurahan Panjehang Kota Palangka Raya
Authors: Rosmilawati Srie , Sari Mita , Rahman Sirojul , Yustin Yustin , Qomah Isti
Published: May 2021

Countries in the world face a big challenge in handling the coronavirus outbreak, which is officially identified by WHO as Corona Virus Disease-19 or abbreviated as Covid-19. This pandemic, which started in the city of Wuhan, China, has caused a global shock because, in the last few decades, we have never experienced a viral outbreak with such a rapid and massive rate and transmission rate like this coronavirus, far above its cousins ​​SARS and MERS viruses as well as Ebola, which had been tormented a few years ago, but was quickly resolved. Educational action on the impact of Covid-19 is very much needed to provide understanding to the people of Panjehang Village where the education contains what Covid-19 is, its effects and dangers, and how to prevent the spread of Covid-19 and to continue the distribution of food packages.
Pemberdayaan Masyarakat Desa dalam Pengembangan Ekonomi Digital kepada Industri Kecil dalam Menghadapi Covid-19 di Desa Mentaren II Pulang Pisau
Authors: Handayani Indah Tri , Bahrianoor Bahrianoor
Published: May 2021

The village of Mentaren II is productive as the center of the snack processing industry. The majority of the people use agricultural land as a livelihood to make various snacks. The management of small industries in this village has been going on for a long time; business actors have their own materials and equipment in their processing practices. Pukades is one of the leading village programs in the direction of development in the village. With this superior village product, it is hoped that it can boost job opportunities in the countryside. So that systematically, it can increase purchasing power and reduce the level of poverty in the village. The sales prospect is quite developed, as evidenced by the many results of their complaining that they are traded in suburban stalls along the Kalimantan road, even directly with buyers. However, this industry's development has faced obstacles since the Covid-19 epidemic, which requires the public not to gather together. This has an impact, especially on business actors who have been relying on conventional marketing systems. At this stage, the community service team visits the village office and meets the village head and village officials, discussing village institutions' activeness, both BUMDes, and Posyantek, in the village. The service team immediately went into the field by visiting several houses that had businesses and conducting brief interviews with the procession of managing activities and various obstacles.
Pemanfaatan Barang Bekas sebagai Alat Peraga Edukasi Ramah Lingkungan Sekolah PAUD di Kota Yogyakarta
Authors: Kencono Dewi Sekar , Winarsih Atik Septi
Published: May 2021

This paper has the aim of demonstrating the importance of environmentally friendly educational props by utilizing used goods. The implementation of teaching and learning activities at Pre-Kindergarten Kota Yogyakarta has problems with limited educational aids (APE). The existence of APE is one of the keys in carrying out the learning process. The low level of teacher creativity in making APE, in this case, becomes the anchor to provide APE for the learning process. This APE can be made by enhancing the creativity between teachers and parents of parents. During the Covid-19 pandemic, teaching and learning activities in Pre-Kindergarten were carried out in their respective homes. To support the use of APE, training on the use of used goods was conducted. Through training in the use of used goods, the aim is to utilize items around and be used as children's learning media for teachers and parents. In addition, to increase the creativity of teachers and parents. Used goods are recycled into useful items. The use of used goods reduces the increasing waste of waste. Through training on the use of used goods as educational props, it can facilitate learning methods both at home and school for early childhood and reduce waste of used goods.
Representasi Local Wisdom dalam Karawitan Melalui Lagu Garuda Pancasila Sebagai Upaya Memperkuat Identitas Bangsa di Kalangan Pemuda-Remaja
Authors: Kurniajati Linuar Setya Rahdiyatmi
Published: May 2021

The development of science and technology and the rapid flow of globalization have indirectly resulted in the degradation of values and the erosion of national identity, especially among youth. Youth become "easy targets" for HOAKS, intolerance, radicalism, SARA issues, negative gangs, crime, terrorism, and other negative views that increasingly erode Pancasila values as part of the national identity. These negative ideas are internalized either through association, social media, negative doctrine, tantalizing offers, mounts of interests of a group, changes in material and educational orientation, and so on. In this regard, karawitan as a cultural product full of local wisdom can be an alternative means of strengthening national identity. This study tries to represent local wisdom in musikals through the Garuda Pancasila song as a material for introducing and practicing gamelan in RW.04 Tukangan youth. The Garuda Pancasila song was chosen as the material for the song because it is one of the national songs; familiar; contains the aesthetic taste of Pancasila, the spirit of nationality, values, the foundation of the state and national identity. The objectives to be achieved from this research are 1) the creation of the Garuda Pancasila song arrangement using the laras slendro gamelan with the creative pop genre, and 2) the training process in the field is expected to encourage the development of a sense of joy playing the gamelan; activated creativity, innovation and expression; the emergence of togetherness, kinship, tolerance, tolerance, empathy, listening to one another, and others, which can strengthen the identity of the nation which is beginning to be eroded.
Influence of behavioral and dietary aspects on children's oral health
Authors: Ramirez Gleice Tibauje Vicente , Okamoto Ana Cláudia , Saliba Tânia Adas , Moimaz Suzely Adas Saliba
Published: May 2021

The purpose of this study was to verify the association of microbiological aspects, behavioral and eating habits that affect the oral health of preschoolers. This is a cross-section of a longitudinal study, with a sample of 42 preschoolers at 30 months of age. A home visit was carried out to conduct an interview on aspects of breastfeeding, early weaning, the child's oral hygiene habits, such as brushing frequency and habits, sharing toothbrushes and kitchen utensils and 24-hour food recall of the preschooler. Was collected 0.5 ml of saliva from the oral floor of the mother and the preschooler using sterile disposable pipettes for culture in a Petri dish. It was observed that there was an association between early weaning (p = 0.046) and bottle use (p = 0.018) with the presence of caries; however, there was no association between the consumption of sugary foods between meals (p = 0.302). The average colony-forming unit (CFU) / ml of S. mutans found in the mothers' saliva was 974421 and the preschool was 135341.9. Extracellular polymer was found in the CFU of samples from 61.90% of mothers and 09.52% of preschoolers. Eating habits such as early weaning and bottle use were associated with the presence of caries. There was no association between microbiological and behavioral aspects that affect oral health and the consumption of sugary foods between meals with the presence of caries in preschoolers.
Analysis of errors according to Newman in solving the spherical triangle
Authors: Sriantini Ari , Cholik Mochamad
Published: May 2021

Penelitian deskriptif dengan pendekatan kualitatif ini bertujuan untuk mengidentifikasi tipe kesalahan dan penyebabnya, serta mengatasinya. Tipe-tipe kesalahan menurut Newman mencakup kesalahan pembacaan, pemahaman terhadap soal, melakukan transformasi, ketrampilan pengerjaan, dan penulisan simbol. Subyek penelitian ini adalah mahasiswa semester pertama Program Studi Nautika yang berjumlah 25 mahasiswa, dengan memakai metode tes, wawancara, dan pengumpulan data. Hasil wawancara dibandingkan dengan jawaban tes mahasiswa, metode dokumentasi digunakan untuk mengetahui nama mahasiswa sebagai subyek penelitian. Berdasarkan luaran penelitian, didapatkan 23,6% mahasiswa mengalami kesalahan pada tahap membaca, 21,8% mahasiswa menghadapi kesalahan dalam tahap pemahaman, 17,3% mahasiswa melakukan kesalahan dalam tahap transformasi, 26,4% mahasiswa mengalami kesalahan pada tahap ketrampilan proses, 10,9 % mahasiswa mengalami kesalahan pada tahap notasi. Kesalahan-kesalahan tersebut disebabkan kurangnya memahami soal, mahasiswa tidak mampu mengubah soal cerita menjadi bahasa matematika, kurang teliti, kurang latihan dalam mengerjakan soal cerita, dan lupa tentang rumus yang digunakan. Dosen diharapkan sering mengenalkan persoalan segitiga bola yang kontekstual kepada mahasiswa untuk meningkatkan pemahaman mahasiswa, mahasiswa harus sering dilatih untuk menyelesaikan soal cerita yang berkaitan dengan segitiga bola dengan berbagai variasi untuk melatih ketelitian dan keterampilannya.
THE EFFECT OF GENDER ROLES AND SEXUAL QUALITY OF LIFE ON MENOPAUSAL COMPLAINTS
Authors: AKSOY DERYA Yeşim , ALTIPARMAK Sümeyye , ÖZTAŞ Hatice Gül
Published: May 2021

This research is conducted with the purpose of identifying the effect of gender roles and sexual quality of life on menopausal complaints. Sample of this cross-sectional research consisted of 306 women in menopausal period.The data was collected using “Personal Information Form”,“Gender Roles Attitude Scale”,“The Sexual Quality of Life-Female (SQOL-F)” and “Menopause Symptoms Rating Scale (MSRS)”.While the average age of women is 53.03±4.91 years, their average age of menopause is 48.58±3.31 years.The total average score that women get from GRAS is 47.61±8.04, total average score they get from SQOL-F is 49.12±11.87 and total average score they get from MSRS is 18.15±9.14. Total average scores they get from Somatic Complaints, Psychological Complaints and Urogenital Complaints sub-dimension of MSRS are 6.64±3.15, 7.15±4.27 and 4.35±3.00, respectively.It was determined that total and all sub-dimension score averages of MSRS increased significantly as the GRAS average score increases in women in menopausal period (p<0.05).In addition, it was also determined that average score from MSRS Urogenital Complaints sub-dimension decreased significantly as SQOL-F average score increases (p<0.05).It was determined that as equalitarian attitude level in terms of gender roles increases, complaints regarding menopausal symptoms increase and urogenital complaints experienced during menopause caused decrease in sexual quality of life
Кримінологічний профіль особи, яка вчинила розголошення державної таємниці
Authors: Тищук В.В. , Сивовол Р.М.
Published: May 2021

У статті досліджено елементи кримінологічного профілю особи, яка вчинила ро­зголошення державної таємниці. Дослідження проведено на основі аналізу статистичних даних Єдиного державного реєстру судових рішень України. У дослідженні були оцінені соціально-демографічні (стать, вік, освіта, національність) та кримінально-правові хара­ктеристики (мотивація злочинної поведінки, одноосібний чи груповий характер злочи­нних дій, тривалість злочинної діяльності, наявність чи відсутність судимості тощо). Уза­гальнення та інтерпретація результатів судових рішень надали можливість змоделювати типовий кримінологічний профіль особи злочинця, що вчинив розголошення державної таємниці, та виділити окремі специфічні характеристики суб’єктів цього злочину.
Struggling, Stupendous Female Artistic Aspirations
Authors: Alban Gillian M.E.
Published: May 2021

Women’s struggles to express themselves artistically, whether in the visual arts or in literature, has never been easy. This writing evaluates women’s creative efforts, from Virginia Woolf’s fictional Judith Shakespeare, to the playwrights Aphra Behn and Elizabeth Inchbald, whose plays scarcely outlived their own era. In the twentieth century, Woolf shows Lily Briscoe painting despite discouragement, and Margaret Atwood and A.S. Byatt’s female characters describe similar artistic struggles to achieve success. The real-life efforts of Sylvia Plath show her creating through the traumas of her life, while Frida Kahlo undertakes a parallel struggle to create her amazing paintings through dreadful pain. These two consummate artists, Plath and Kahlo, immortalize woman’s agonizing self-expression in their verbal and visual portraits, overcoming considerable obstacles. This work presents the historical toils and fictional accounts of women artists in their attempts at artistic self-expression, proving that such efforts come at a high cost to the artist even to this day.
Seeing the Belly Dance as a Feminist Possibility: Gaze, Gender and Public Space in İstanbul
Authors: Eğrikavuk Işık
Published: May 2021

This paper discusses the ancient form of belly dance as an example to speak more in depth about the public spaces of Istanbul, where the female body is constantly under surveillance by the male gaze. Over thousands of years, the ancient dance form of belly dance has been transformed from a collective women’s ritual to a form of entertainment that serves the male gaze. This paper looks for the possibilities tore-define belly dance as a feminist counter strategy to revive its essence. Framed by the Muted Group Theory, this paper also exemplifies various artworks and strategies produced by female artists and analyze them in the light of this theory. It also searches for redefining the belly dance as part of a feminist identity and asks whether these artistic strategies could be pathways in re-defining belly dance as a feminist practice.
Durdurun Uçağı, İnecek Var! Asi Kızlara Uykudan Önce Hikâyeler
Authors: Behçetoğulları Pembe
Published: May 2021

Bir kız çocuğu asi olur, olmalıdır, ta ki kendi yolunu kendi bildiği gibi çizene kadar; çünkü hayat ona ‘dur’ der, ‘sen kızsın’ der, ‘yapma’ der, ‘önüne bak’ der, ‘konuşma’ der, ‘düzgün otur’ der, ‘sokakta şarkı söyleme’ der, ve hatta ‘sokağa çıkma’ der. Bunları duya duya, bir kız çocuğu, eğer yeterince sindirilmemişse, eğer korkutulup susturulmamışsa tamamen, birazcık asi olur mutlaka. Olsun da!
Effect of Air Quality on the Risk of Emergency Room Visits in Patients With Atrial Fibrillation
Authors: Liang Bin , He Xiaonan , Du Xin , Liu Xiaoxia , Ma Changsheng
Published: May 2021

Background: We investigated the effect of particulate matter with aerodynamic diameter <2.5 μm (PM2.5) and meteorological conditions on the risk of emergency room visits in patients with atrial fibrillation (AF) in Beijing, which is considered as a monsoon climate region.

Methods: In this case-crossover design study, medical records from patients with AF who visited the Critical Care Center in the Emergency Department of Anzhen Hospital from January 2011 through December 2014 and air quality and meteorological data of Beijing during the same period were collected and analyzed using Cox regression and time-series autocorrelation analyses.

Results: A total of 8,241 patients were included. When the average PM2.5 concentration was >430 μg/m3, the risk of emergency room visits for patients with uncomplicated AF, AF combined with cardiac insufficiency, and AF combined with rheumatic heart disease increased by 12, 12, and 40%, respectively. When the average PM2.5 concentration was >420 μg/m3, patients with AF combined with diabetes mellitus had a 75% increased risk of emergency room visits, which was the largest increase in risk among all types of patients with AF. When the average PM2.5 concentration was >390 μg/m3, patients with AF combined with acute coronary syndrome had an approximately 30% increased risk of emergency room visits, which was the highest and fastest increase in risk among all types of patients with AF. The risk of emergency room visits for patients with AF was positively correlated with air quality as the time lag proceeded, with an autocorrelation coefficient of 0.223 between the risk of emergency room visits and air quality in patients with AF on day 6 of the time lag.

Conclusion: Exposure to certain concentrations of PM2.5 in a monsoon climate region significantly increased the risk of emergency room visits in patients with AF.
Differential Erosion and Sedimentation Process at the Longmenshan Foreland Basin, Eastern Margin of the Tibetan Plateau: Evidence From Analog Experiments
Authors: Luo Qiang , Deng Bin , Guang Youhui , He Yu , Guo Hongbin , Huang Jiaqiang , Yang Rongjun , Yu Hao , Zhang Jing
Published: May 2021

We use analog experiments to investigate the influence of rapid filling of a foreland basin system during the development of a fold-and-thrust belt, in particular, the change of erosion–sedimentation along the strike in the Longmenshan foreland basin. A negative relationship between wedge geometries and the magnitude of erosion can be found; increased erosion results in out-of-sequence thrusting and fault reactivation in the wedge hinterland, to limit the forelandward propagation of the wedge. In contrast, increased sedimentation facilitates the forelandward propagation of the wedge. We focus on a natural example of the Longmenshan foreland basin, where a change in erosion–sedimentation along the strike during the Late Cretaceous to Cenozoic is well documented. The comparison between our model and seismic sections indicates that such along-strike variation results in a rejuvenated foreland basin restricted to the southwestern part of the western Sichuan Basin in the Cenozoic.
Co-digestion of Oil Palm Trunk Hydrolysate and Slaughterhouse Wastewater for Biohydrogen Production in a Fixed Bed Reactor by Immobilized Thermoanaerobacterium thermosaccharolyticum KKU19 on Expanded Clay
Authors: Khamtib Sontaya , Sittijunda Sureewan , Imai Tsuyoshi , Reungsang Alissara
Published: May 2021

The goal of this study was to evaluate the use of expanded clay as a support material for Thermoanaerobacterium thermosaccharolyticum KKU19 to produce hydrogen from oil palm trunk hydrolysate (OPT) and slaughterhouse wastewater (SHW) in a fixed-bed reactor (FBR) under non-sterile conditions. The effects of hydraulic retention time (HRT) on the performance of the FBR were also investigated. The FBR was operated at an OPT hydrolysate to SHW ratio of 2.55:1 (v:v), 60°C, initial pH 6.5, and 1.2 mg (as total volatile solids/g expanded clay) of T. thermosaccharolyticum KKU19 immobilized on expanded clay. A maximum hydrogen production rate (HPR) and hydrogen yield (HY) of 7.15 ± 0.22 L/L day and 234.45 ± 5.14 mL H2/g-COD, respectively, were obtained at an HRT of 6 h. Long-term operation of FBR at 6 h HRT indicated that expanded clay efficiently immobilizes T. thermosaccharolyticum KKU19, for which an HPR of 6.82 ± 0.56 L H2/L day, and an HY of 231.99 ± 19.59 mL H2/g-COD were obtained. Furthermore, the COD removal efficiency of 30% obtained under long-term operation was comparable to that under short-term operation at an HRT of 6 days. Butyric and acetic acids were the main soluble metabolite products, thereby indicating a butyrate–acetate type fermentation. Our findings indicate that expanded clay is an effective support material that contributes to the protection of microbial cells and can be used for long-term operation.
First Evidence of Retrospective Findings of Microplastics in Harbour Porpoises (Phocoena phocoena) From German Waters
Authors: Philipp Carolin , Unger Bianca , Ehlers Sonja M. , Koop Jochen H. E. , Siebert Ursula
Published: May 2021

Microplastic ingestion by lower trophic level organisms is well known, whereas information on microplastic ingestion, egestion and accumulation by top predators such as cetaceans is still lacking. This study investigates microplastics in intestinal samples from harbour porpoises (Phocoena phocoena) found along the coastline of Schleswig-Holstein (Germany) between 2014 and 2018. Out of 30 individuals found along the North Sea (NS) and the Baltic Sea (BS) coast, 28 specimens contained microplastic. This study found a relationship between the nutritional status of cetaceans and the amount of found microplastics. Harbour porpoises with a good or moderate nutritional status contained a higher number of microplastics, when compared with specimens in a poor nutritional status. In addition, when individuals died accidently due to suspected bycatch in gillnets, where a feeding event is highly assumed or a pharyngeal entrapment happened, the microplastic burden was higher. In total, 401 microplastics (≥100 μm), including 202 fibres and 199 fragments were found. Intestines of the specimens of the BS contained more microplastics than the ones from the NS. Differences in the share of fibres could be revealed: for BS fibres constituted 51.44% and for NS, fibres constituted 47.97%. The polymers polyester, polyethylene, polypropylene, polyamide, acrylic (with nitrile component) and an acrylic/alkyd paint chip (with styrene and kaolin components) were identified. This is the first study investigating the occurrence of microplastics in harbour porpoises from German waters and will, thus, provide valuable information on the actual burden of microplastics in cetaceans from the North and Baltic Seas.
Fecal Enterotoxigenic Bacteroides fragilis–Peptostreptococcus stomatis–Parvimonas micra Biomarker for Noninvasive Diagnosis and Prognosis of Colorectal Laterally Spreading Tumor
Authors: Shen Xiaonan , Li Jialu , Li Jiaqi , Zhang Yao , Li Xiaobo , Cui Yun , Gao Qinyan , Chen Xiaoyu , Chen Yingxuan , Fang Jing-Yuan
Published: May 2021

Objective

Up to now, non-invasive diagnosis of laterally spreading tumor (LST) and prediction of adenoma recurrence after endoscopic resection of LSTs is inevitable. This study aimed to identify a microbial signature with clinical significance of diagnosing LSTs and predicting adenoma recurrence after LSTs colectomy.

Methods

We performed 16S rRNA sequencing in 24 mucosal samples, including 5 healthy controls (HC), 8 colorectal adenoma (CRA) patients, and 11 LST patients. The differentiating microbiota in fecal samples was quantified by qPCR in 475 cases with 113 HC, 208 CRA patients, 109 LST patients, and 45 colorectal cancer (CRC) patients. We identified differentially abundant taxa among cases and controls using linear discriminant analysis effect size analysis. ROC curve was used to evaluate diagnostic values of the bacterial candidates. Pairwise comparison of AUCs was performed by using the Delong’s test. The Mantel-Haenszel hazard models were performed to determine the effects of microbial compositions on recurrence free survival.

Results

The microbial dysbiosis of LST was characterized by relative high abundance of the genus Lactobacillus-Streptococcus and the species enterotoxigenic Bacteroides fragilis (ETBF)–Peptostreptococcus stomatis (P. stomatis)–Parvimonas micra (P. micra). The abundance of ETBF, P. stomatis, and P. micra were steadily increasing in LST and CRC groups. P. stomatis behaved stronger value on diagnosing LST than the other two bacteria (AUC 0.887, 95% CI 0.842–0.931). The combination of P. stomatis, P. micra, and ETBF (AUC 0.922, 95% CI 0.887–0.958) revealed strongest diagnostic power with 88.7% sensitivity and 81.4% specificity. ETBF, P. stomatis, and P. micra were associated with malignant LST (PP.stomatis = 0.0015, PP.micra = 0.0255, PETBF = 0.0169) and the abundance of IL-6. The high abundance of P. stomatis was related to the adenoma recurrence after LST resection (HR = 3.88, P = 0.008).

Conclusions

Fecal microbiome signature (ETBF–P. stomatis–P. micra) can diagnose LSTs with high accuracy. ETBF, P. stomatis, and P. micra were related to malignant LST and P. stomatis exhibited high predictive value on the adenoma recurrence after resection of LSTs. The fecal microbiome signature of LST may provide a noninvasive alternative to early detect LST and predict the adenoma recurrence risk after resections of LSTs.
Epithelial-Mesenchymal Transition in Colorectal Carcinoma: Comparison Between Primary Tumor, Lymph Node and Liver Metastases
Authors: Pavlič Ana , Urh Kristian , Štajer Katarina , Boštjančič Emanuela , Zidar Nina
Published: May 2021

There is emerging evidence suggesting that epithelial-mesenchymal transition (EMT) and mesenchymal-epithelial transition (MET) play an important role in colorectal carcinoma (CRC), but their exact role remains controversial. Our aim was to analyze the miR-200 family as EMT markers and their target genes expression at invasive tumor front and in nodal and liver metastases. Sixty-three formalin-fixed paraffin-embedded tissue samples from 19 patients with CRC were included. Using a micropuncture technique, tissue was obtained from central part and invasive front of the primary tumor, and nodal and liver metastases. Expression of the miR-200 family and their target genes CDKN1B, ONECUT2, PTPN13, RND3, SOX2, TGFB2 and ZEB2 was analyzed using real-time PCR. We found miR-200 family down-regulation at invasive front compared to central part, and up-regulation of miRNA-200a/b/c and miR-429 in metastases compared to invasive front. At invasive front, TGFB2 was the only gene with inverse expression to the miR-200 family, whereas in metastases inverse expression was found for ONECUT2 and SOX2. CDKN1B, PTPN13 and ZEB2 were down-regulated at invasive front and up-regulated in metastases. Our results suggest the involvement of partial EMT at invasive tumor front, and partial MET in metastases in CRC, based on miR-200 family and its target genes expression.
Integrated Strategy of Network Pharmacological Prediction and Experimental Validation Elucidate Possible Mechanism of Bu-Yang Herbs in Treating Postmenopausal Osteoporosis via ESR1
Authors: Xia Hanting , Liu Jiangyuan , Yang Wenlong , Liu Min , Luo Yunfeng , Yang Zhijun , Xie Jingbo , Zeng Huiliang , Xu Rui , Ling Houfu , Zeng Qinghe , Xu Huihui , Fang Liang , Wang Hongyu , Tong Peijian , Jin Hongting , Yang Fengyun
Published: May 2021

Postmenopausal osteoporosis (PMOP) is a type of bone metabolism disease-related to estrogen deficiency with an increasing incidence. Traditional Chinese (TCM) has always been used and showed effectiveness in treating PMOP. In the current study, Bu-Yang herbs were considered to be the most frequently used and efficient TCM herbs in PMOP treatment. However, chemical and pharmacological profiles were not elucidated. Network pharmacology was conducted on representative Bu-Yang herbs (Yin-Yang-Huo. Du-Zhong, Bu-Gu-Zhi, Tu-Si-Zi) to investigate the mechanism of Bu-Yang herbs on PMOP. Chemical compounds, potential targets, and disease related genes were available from the corresponding database. Results showed that Bu-Yang herbs could interact with ESR1 and estrogen signaling pathways. For further validation, the Bu-Yang decoction (BYD), formula consisted of the above-mentioned 4 Bu-Yang herbs was presented for experimental validation. In vivo, BYD significantly reversed ovariectomy (OVX)-induced osteoporosis progress in a dose-dependent manner by up-regulation of bone mineral density and amelioration of bone microarchitecture. In vitro, BYD dramatically improved the proliferation and mineral nodules formation of osteoblasts. Both in vitro and in vivo results illustrated that the phenotype change induced by BYD is correlated with up-regulated of ESR1 and activation of the β-catenin pathway. Meanwhile, inhibition of ESR1 by ICI182, 780 blocked the osteogenic phenotype and β-catenin pathway activation induced by BYD. In conclusion, the current study suggested that Bu-Yang herbs are the most useful TCM herbs in treating PMOP. Furthermore, the integrated strategy of network pharmacology prediction with experimental validation suggested that BYD exerted its anti-PMOP via ESR1 and the downstream mechanism might be activation of the β-catenin signaling pathway.
Integrated Gene Co-expression Analysis and Metabolites Profiling Highlight the Important Role of ZmHIR3 in Maize Resistance to Gibberella Stalk Rot
Authors: Sun Yali , Ruan Xinsen , Wang Qing , Zhou Yu , Wang Fang , Ma Liang , Wang Zhenhua , Gao Xiquan
Published: May 2021

Gibberella stalk rot (GSR) caused by Fusarium graminearum is one of the most devastating diseases causing significant yield loss of maize, and GSR resistance is a quantitative trait controlled by multiple genes. Although a few quantitative trait loci/resistance genes have been identified, the molecular mechanisms underlying GSR resistance remain largely unexplored. To identify potential resistance genes and to better understand the molecular mechanism of GSR resistance, a joint analysis using a comparative transcriptomic and metabolomic approaches was conducted using two inbred lines with contrasting GSR resistance, K09 (resistant) and A08 (susceptible), upon infection with F. graminearum. While a substantial number of differentially expressed genes associated with various defense-related signaling pathways were identified between two lines, multiple hub genes likely associated with GSR resistance were pinpointed using Weighted Gene Correlation Network Analysis and K-means clustering. Moreover, a core set of metabolites, including anthocyanins, associated with the hub genes was determined. Among the complex co-expression networks, ZmHIR3 showed strong correlation with multiple key genes, and genetic and histological studies showed that zmhir3 mutant is more susceptible to GSR, accompanied by enhanced cell death in the stem in response to infection with F. graminearum. Taken together, our study identified differentially expressed key genes and metabolites, as well as co-expression networks associated with distinct infection stages of F. graminearum. Moreover, ZmHIR3 likely plays a positive role in disease resistance to GSR, probably through the transcriptional regulation of key genes, functional metabolites, and the control of cell death.
The Association Between Emotion Regulation, Physiological Arousal, and Performance in Math Anxiety
Authors: Pizzie Rachel G. , Kraemer David J. M.
Published: May 2021

Emotion regulation (ER) strategies may reduce the negative relationship between math anxiety and mathematics accuracy, but different strategies may differ in their effectiveness. We recorded electrodermal activity (EDA) to examine the effect of physiological arousal on performance during different applied ER strategies. We explored how ER strategies might affect the decreases in accuracy attributed to physiological arousal in high math anxious (HMA) individuals. Participants were instructed to use cognitive reappraisal (CR), expressive suppression (ES), or a “business as usual” strategy. During the ES condition, HMA individuals showed decreases in math accuracy associated with increased EDA, compared to low math anxious (LMA) individuals. For both HMA and LMA groups, CR reduced the association between physiological arousal and math accuracy, such that even elevated physiological arousal levels no longer had a negative association with math accuracy. These results show that CR provides a promising technique for ameliorating the negative relationship between math anxiety and math accuracy.
Research on Disability Grading Based on ICF Functional Framework: Empirical Evidence From Zhejiang Province, China
Authors: Liu Huan
Published: May 2021

Through assignment method, the total score of disability in multiple dimensions is obtained, and it is divided into five functional states—severe disability, partial disability, moderate disability, mild disability, and health—according to the score, and the probability of death is constructed. Using the Chinese Longitudinal Healthy Longevity Survey (CLHLS) database tracking survey data, by constructing a multistate transition probability matrix, the empirical calculation of the multistate disability transfer probability, with the help of the sixth national census data, we estimated maintenance time of each state, life expectancy, etc. The results show that the 3 year transfer probability of the initial healthy elderly is the highest, and the mortality rate is also the lowest. It can be found that the disability state transition probability measurement based on the data is more accurate than the model estimation; the disability scale and life expectancy estimated based on the multistate transition probability matrix are more reliable.
A Systematic Review of Robotic Rehabilitation for Cognitive Training
Authors: Yuan Fengpei , Klavon Elizabeth , Liu Ziming , Lopez Ruth Palan , Zhao Xiaopeng
Published: May 2021

A large and increasing number of people around the world experience cognitive disability. Rehabilitation robotics has provided promising training and assistance approaches to mitigate cognitive deficits. In this article, we carried out a systematic review on recent developments in robot-assisted cognitive training. We included 99 articles in this work and described their applications, enabling technologies, experiments, and products. We also conducted a meta analysis on the articles that evaluated robot-assisted cognitive training protocol with primary end users (i.e., people with cognitive disability). We identified major limitations in current robotics rehabilitation for cognitive training, including the small sample size, non-standard measurement of training and uncontrollable factors. There are still multifaceted challenges in this field, including ethical issues, user-centered (or stakeholder-centered) design, the reliability, trust, and cost-effectiveness, personalization of the robot-assisted cognitive training system. Future research shall also take into consideration human-robot collaboration and social cognition to facilitate a natural human-robot interaction.
Problemáticas de la docencia universitaria ecuatoriana en tiempos de COVID19
Authors: Salamea Nieto Rosa Marianela , Campoverde Romero Sandra Elizabeth , Cedillo Chalaco Luis Fernando , Campuzano Vásquez John Alexander
Published: May 2021

El coronavirus (covid-19), ha sumido a los países del mundo en un apuro, no solo sanitario y económico, sino también educativo, que ha llevado a muchas naciones a la suspensión de las actividades docentes tradicionales. Ecuador es parte de esta realidad, su sistema universitario está inmerso en una urgente transición de las clases presenciales a formatos online. La Universidad Técnica de Machala es parte de este crítico momento, el cual ha generado varias problemáticas para los docentes, que de forma abrupta y en un período inusual los ha llevado a migrar sus clases a un formato educativo distinto al tradicional, constituyéndose un salto apresurado a la universidad del nuevo siglo, en donde la tecnología pasó de ser una herramienta esporádica a convertirse en una parte fundamental en la cátedra, marcando un nuevo nivel de fatiga y estrés en los educadores. Esta investigación usó una encuesta online que recogió las respuestas de docentes de la Universidad Técnica de Machala, para identificar el nivel de fatiga y estrés por el cual están atravesando por la virtualización de sus clases, debido a la pandemia del covid-19, obteniendo datos respecto a las problemáticas presentadas (logísticas, tecnológicas, pedagógicas y socioafectivas), y la edad (intervalos) de cada uno de ellos, los que son analizados usando un modelo ANOVA de doble vía. Los principales resultados muestran que el nivel de fatiga y estrés en los docentes universitarios se ha visto incrementado, y marca diferencias estadísticamente significativas respecto a las edades, y no significativas en cada problemática manifestada.
El trabajo con inteligencia emocional en psicoterapia integradora humanista
Authors: Gimeno-Bayón Cobos Ana
Published: May 2021

Tras una breve presentación del modelo de Psicoterapia Integradora Humanista (del que son creadores la propia autora y Ramón Rosal), y de sintetizar el papel y tratamiento que tienen las emociones en dicho modelo, el artículo aborda el constructo de la inteligencia emocional. Desde el enfoque que proponen Salovey y Mayer, el texto va ascendiendo uno por uno a través de los cuatro grandes niveles de este modelo de inteligencia emocional, y de las subhabilidades integrantes de cada uno de ellos. Conforme va avanzando en esta descripción sistemática, va apuntando algunas intervenciones psicoterapéuticas que se realizan desde la Psicoterapia Integradora Humanista para el aprendizaje de cada una de estas habilidades.
Formas de afrontamiento, mecanismos de defensa e inteligencia emocional: comparación teórica y evaluación empírica de su frecuencia y funcionalidad
Authors: Páez Darío , Velasco C. , Campos M.
Published: May 2021

En este artículo compararemos las grandes estrategias de afrontamiento con los mecanismos de defensa, revisaremos los estudios que muestran sus efectos y su funcionalidad. También examinaremos su asociación con indicadores de Inteligencia Emocional (IE), así como con algunos rasgos de la personalidad. De esta forma, el lector tendrá una visión del carácter normal de muchas respuestas de afrontamiento, corrigiendo el sesgo demasiado idealista de la concepción de los mecanismos de defensa maduros –al igual que la mayoría de una población normal presenta síntomas, los mecanismos de defensa neuróticos son mayoritarios y dominantes–. En el último apartado se expondrán los ítems de la escala más relevante de medida para los mecanismos de defensa, el DSQ-40, que servirá para tener una idea mediante preguntas de auto-informe de cuál es el contenido de estos mecanismos.