bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessment of knowledge, attitude and practice of kangaroo mother care among postnatal women attending at Hiwot Fana Specialized University Hospital, Harar Town, Eastern Ethiopia
Authors: Yezengaw Telksew Yelma
Published: December 2022

Background: - Kangaroo Mother Care is a powerful method to promote the health and well-being of Low Birth Weight babies. One of the main reasons that Low Birth Weight babies are at greater risk of illness and death is that they lack ability to control their body temperature. Globally 25 mil-lion infants (17%) are born with a low birth weight and most of these occur in low-income countries.
Objective: - The aim this study is to assess knowledge, attitude and practice of Kangaroo mother care among mothers in Hiwot Fana comprehensive and specialized university hospital, Eastern Ethiopia.
Method:- A cross-sectional study was employed on mothers admitted to post-natal ward in Hiwot Fana comprehensive and specialized university hospital from January 12/2021 to January 26/2021. Random sampling method was used to select the study participants. The data was collected using semi structured interview administered questionnaire by four female data collectors who have diploma in midwifery/nursing. After checking completeness, the collected data was entered in to SPSS version 22.0 for analysis. The result of analysis was presented by using frequencies, summary measures, texts, tables, Charts and graphs
Result: - The overall study finding revealed that 34.1% mothers who participated in this study had good knowledge and 65.9% had poor knowledge towards KMC. About 18.9% respondent had positive attitude and 81.1% had negative attitude. In regards of practice, 18.4 % good and 81.6% had poor practice towards KMC.
Conclusion and Recommendation:-This study shows that there is poor knowledge, negative attitude and poor practice of KMC. Giving awareness on KMC as well as practice, training were significantly associated with level of knowledge and practice. Moreover, orientation was statistically associated with attitude. Thus, intervention that should focus on creating awareness, training KMC and positive attitude creation are required to strengthen KMC knowledge, attitude and practice in postnatal mothers.
Late Initiation of Antenatal Care and Associated Factors Among Antenatal Care Attendees in governmental Health Centers of Harar Town, Ethiopia
Authors: Yezengaw Telksew Yelma
Published: December 2022

Introduction: Antenatal care is a type of care given for women during pregnancy and is a key strategy for reducing maternal and neonatal morbidity and mortality. The goal of Antenatal care is to prevent health problems of pregnant women through detection of complications and treatment of pregnancy related illness.
Objective: This study aims to Assessment late initiation of antenatal care and associated factors among antenatal care attendants in Governmental Health Centers of Harar Town, Ethiopia March 05 – 20/2020.
Methodology: A quantitative cross-sectional institution based study was used to assess late initiation of antenatal care and factors associated with it in Governmental Health Centers of Harar Town. The sampling technique was Systematic random sampling method was used. Two hundred Seven pregnant women who attend ANC were included in this study. Data was entered, coded and analyzed using SPSS, version 20. Descriptive statistics like frequencies and percentages was used to present the result.
Result: Out of 207 pregnant mothers included in this study, 136 (65.7%) pregnant mothers started their first ANC visit early while the remaining 71 (34. %) pregnant mothers started ANC late. Multivariate analysis revealed that Age, Gravidity and Waiting time were associated with independent variable. Those women whose age group 20-25 years were 3 times more likely having early booking than those age group less than 20 years (AOR=3.374,95% CI=[1.117-10.189] women who had gave live birth were 2 times more likely having early booking than those women who had a history of child death(AOR=2.686,95% CI=[1.005-7.178] Those women had waited time of 1:30-2hours before having the service were 18% less likely having early booking than those women who had waited for less than 30minute (AOR=0.082,95%CI: 0.007-1.019)
Conclusion: The results of this study indicated that two-third of the respondents had started their ANC within the recommended time (65.7%) and the rest one-third were booked late (34.3%). The Respondents educational level, knowledge on the importance of ANC service utilization, Source of the information which contributed to book timely for the current pregnancy and the advice given on the time of first ANC booking are significantly and positively influenced early initiation of ANC in Harar.
THE INFLUENCE OF STRATEGIC MANAGEMENT ACCOUNTING ASPECTS ON BANK PERFORMANCE
Authors: Shodriani Idzna Nur , Izzaty Khairina Nur
Published: December 2022

This research purpose to develop a broad conceptualization of strategic management accounting and examine the influence of aspects of strategic management accounting on organizational performance at commercial banks and BPR in Kota Tegal. This type of research is quantitative and the data analysis uses SPSS ( Statistical Product and Service Solutions ) 25. The sampel of this research is the head of the office leadership of commercial bank and BPR in Kota Tegal. The result of this research indicate that organizational structure and organizational climate hanve a positive effect on organizational performance while organizational resources and information system have no effect on organizational performance.
THE EFFECT OF INFORMATION TECHNOLOGY, ORGANIZATIONAL COMMITMENTS, AND INTERNAL CONTROL SYSTEMS ON VILLAGE FUND MANAGEMENT ACCOUNTABILITY
Authors: Ebrianty Alfina , Meirini Dianita
Published: December 2022

This study aims to examine the effect of the variables of using information technology, organizational commitment, and internal control systems on the accountability of village fund management partially and simultaneously. This research uses quantitative methods. Determination of the sample using a non-probability sampling technique with criteria for village officials who serve as village heads, village secretaries, heads of financial affairs, heads of planning affairs, heads of administrative and general affairs, heads of government sections, heads of welfare sections, and heads of service sections. The data used in the form of primary data by distributing questionnaires using a Likert scale to 122 village officials. The statistical methods used are data quality test, multiple linear regression analysis, classical assumption test, and hypothesis testing with the help of the IBM SPSS 25 application. From the results of this study, it was found that the use of information technology and internal control systems partially had a positive and significant effect on village fund management accountability, while organizational commitment partially did not have a positive effect on village fund management accountability. Based on the F test, it was found that the use of information technology, organizational commitment, and the internal control system simultaneously had a positive and significant effect on the accountability of village fund management.
FACTORS AFFECTING OF SHARIA ACCOUNTING STUDENTS TO WORK IN SHARIA FINANCIAL INSTITUTIONS
Authors: 'Athifah Nabilatul , Adinugraha Hendri Hermawan
Published: December 2022

Penelitian ini bertujuan untuk mengetahui pengaruh minat kerja pada mahasiswa akuntansi syariah di IAIN Pekalongan pada Lembaga Keuangan Syariah. Metode pengumpulan data pada penelitian ini adalah metode angket, yaitu dengan membagikan daftar pertanyaan (kuesioner) untuk diisi atau dijawab oleh responden kepada mahasiswa akuntansi syariah. Untuk mengelola dan menganalisis data yang diperoleh serta melakukan penelitian analisis kuantitatif menggunakan teknik analisis regresi linier berganda bertujuan untuk memperoleh pemahaman yang komprehensif tentang hubungan antar variabel dengan bantuan program SPSS 24. Hasil pengujian menunjukkan bahwa variabel pertimbangan pasar kerja, lingkungan kerja, dan spiritualitas tidak berpengaruh terhadap minat mahasiswa akuntansi syariah untuk bekerja di lembaga keuangan syariah, sedangkan variabel penghargaan finansial dan pengetahuan akuntansi syariah memiliki pengaruh yang signifikan terhadap minat mahasiswa akuntansi syariahbekerja di lembaga keuangan syariah, kemampuan prediksi kedua variabel tersebut terhadap minat 71,8% mahasiswa akuntansi syariah bekerja di lembaga keuangan syariah dan sisanya 26,9% dipengaruhi oleh faktor eksternal lainnya.
Risk factors of lethal outcomes of tuberculosis in a region with low population density (Kamchatskiy kray)
Authors: Gromov A. V. , Sterlikov S. A. , Mikhaylova Yu. V.
Published: December 2022

The objective: evidence-based study of the factors inﬂuencing tuberculosis mortality in the Kamchatskiy Kray as a territory withlow population density.

Subjects and Methods. A retrospective cohort study of the unfavorable course of tuberculosis in 512 patients with tuberculosis (new cases and relapses) was carried out. A univariate and multivariate analysis of risk factors for a lethal outcome of tuberculosis was performed.

Results. In a univariate analysis, the incidence of death from tuberculosis among increased in older patients (p < 0.0001), among the unemployed, pensioners and disabled (p = 0.02), homeless (p = 0.01), persons who failed to undergo ﬂuorography for 2 years or more (p = 0.004), patients with a positive result of sputum smear test at registration (p = 0.003), and those suﬀering from alcoholism (p = 0.03), and decreased in patients who were actively detected (p < 0.0001 ). There was no inﬂuence on the probability of death from tuberculosis in the registration group by such parameters as new cases/relapses (p = 0.2), male/female (p = 0.09), urban/rural area of residence (p = 0.7), belonging to the indigenous population (p = 0.6), resistance to rifampicin (p = 1), cardiovascular diseases (p = 0.5), and smoking (p = 0.3). In multivariate analysis, an independent factor that reduced the risk of death was the active detection of tuberculosis patients (aOR = 0.2, p = 0.02).

Conclusion. To reduce the risk of death from tuberculosis in an area with low population density (Kamchatskiy Kray), the priority should be given to improvement of active detection of tuberculosis cases; the proportion of tuberculosis patients detected during preventive screening should be used as an parameter of this improvement.
Pelatihan Kemampuan Resiliensi Pada Mahasiswa Penerima Beasiswa Yayasan X Dalam Menghadapi Tantangan di Kehidupan Sehari-Hari
Authors: Cunong Kevin Harry Anugerah , Aisah Nurul , Nathania Reinita , Santoso Leticia Virginia , Darmananda Muhammad Ridho , Wira Indarta , Setiawan Jenny Lukito , Virlia Stefani
Published: December 2022

Mahasiswa seringkali dihadapkan pada permasalahan dan tantangan baik dalam kehidupan sehari-hari, maupun perkuliahan. Mahasiswa penerima beasiswa memiliki tekanan yang lebih pada aspek akademik, regulasi, dan kewajiban pembelajaran. Hal tersebut menyebabkan mahasiswa penerima beasiswa menjadi mudah stress, cemas, depresi hingga memunculkan perilaku destruktif. Kondisi ini juga dialami oleh para mahasiswa penerima beasiswa Yayasan X. Tantangan yang dihadapi antara lain adaptasi diri, manajemen waktu, mengalami pemikiran berlebihan akan studi lanjut serta karir di masa depan. Adanya berbagai tantangan dan permasalahan tersebut menyebabkan mahasiswa penerima beasiswa menjadi kurang terbuka, pesimis, mudah putus asa, stress, depresi, hingga melukai diri sendiri. Berdasarkan permasalahan tersebut, peneliti tertarik untuk memberikan pelatihan secara luring guna mengembangkan kemampuan resiliensi mahasiswa penerima beasiswa Yayasan X. Dari pelatihan ini mahasiswa akan memiliki kapasitas untuk bangkit, serta kembali siap dalam menghadapi tantangan maupun situasi sulit dalam kehidupan sehari-hari. Pelaksanaan pelatihan terdiri dari penyampaian materi, kegiatan praktek, refleksi, serta evaluasi. Hasil pelatihan ini menunjukkan tidak ada perubahan pengetahuan yang signifikan, namun terdapat pengembangan kemampuan-kemampuan baru yang dimiliki oleh mahasiswa penerima beasiswa Yayasan X, diantaranya kemampuan resiliensi, pemecahan masalah, mengenali potensi diri, mengembangkan hubungan sosial, berpikir kritis, proaktif, dan pengendalian emosi yang dapat diterapkan dalam kehidupan sehari-hari.
PEMETAAN DIGITAL UNTUK MENDUKUNG PENGEMBANGAN KAWASAN WISATA PECINAN JAMBLANG
Authors: Ghozali Achmad Aprizal , Andana Bagus Tri , Santoputri Cintiya Dewanti , Azizah Latifah Nur , Nurzaqi Dave Vian , Rachmat Mohamad Nurfian , Sofwan Gyanrahma Indrajid , Roswati  , Lodhita Felicia , Lesmana Cindrawaty , Djakaria Elliati , Nurrachman Mohamad Irfan , Santoso Miky Endro , Darmayanti Tessa Eka , Kusbiantoro Krismanto , Leonardo  , Sugata Ferlina
Published: December 2022

Jamblang adalah sebuah desa di tepi Sungai Jamblang di kecamatan Depok, Kabupaten Cirebon yang memiliki sejarah permukiman komunitas Tionghoa yang cukup tua. Peninggalan ini menjadi salah satu potensi lokal yang ada di Desa Jamblang untuk dapat dikembangkan jadi kawasan wisata Pecinan Jamblang. Kawasan Pecinan Jamblang yang belum tertata dengan baik, masih banyak perlu menjadi target pengembangan. Tujuan dari kegiatan pengabdian kepada masyarakat adalah melakukan mengumpulkan data untuk mengembangkan desa Jamblang menjadi kawasan wisata Pecinan. Kegiatan dilakukan dalam empat tahap, yaitu tahap screening, tahap pengumpulan data, tahap pengolahan data, serta yang terakhir tahap evaluasi dan tindak lanjut. Survei dan pemetaan wilayah dilakukan secara kolaboratif dengan melibatkan partisipasi masyarakat setempat dalam pengambilan data dan pengumpulan aspirasinya. Data dikumpulkan melalui wawancara, survei, observasi, pengukuran langsung, foto udara dengan Unmanned Aerial Vehicle, dan pameran. Seluruh data diolah menjadi beberapa luaran seperti pemetaan digital Pecinan Jamblang dan observasi bangunan-bangunan tua pada Pecinan Jamblang yang dapat mendukung pengembangan kawasan wisata Pecinan Jamblang.
Assessing the Borta Reservoir using physicochemical parameters, Oromia Regional State, Ethiopia
Authors: Kuma Tolera , Hailu Yohanis
Published: December 2022

This study was conducted in the Borta Reservoir (Ethiopia) to portray physicochemical parameters between September 2018 and July 2019 for three data collection sessions. Accordingly, the sampling site was purposely selected perimeter-wise from the Borta Reservoir based on the distance from human settlements; anthropogenic effect and accessibility for the study three stations (sampling sites) were purposely selected perimeter-wise and the sites were coded as Site one (S1), site two (S2), and site three (S3). Water samples were collected monthly for three sample collection sessions. Samples were collected from each site and transported to the Limnology Laboratory and other parameters were measured on-site using a pre-calibrated portable instrument. SPSS version 20 was used for the statistical analysis. The recorded physicochemical parameters were in the range of freshwaters. It was evident that the Borta Reservoir had been showing signs of water quality loss over time. This could have resulted from stressors linked to anthropogenic sources from domestic wastes and pollutants from agricultural lands. This study suggested a restoration action be undertaken.
Ozone therapy in veterinary medicine: clinical indications and techniques
Authors: Sumida Juliana Midori , Hayashi Ayne Murata
Published: December 2022

Ozone therapy application and research have increased recently. The mixture of oxygen-ozone (O2-O3) has been used as a therapeutic agent for the treatment of several diseases with beneficial effects. This brief literature review has the objective of disclosing the mechanisms of action and main clinical indications and possibilities of ozone therapy for different conditions. The local and systemic approaches and techniques described for human treatment can be easily transposed for use in animals, such as rectal insufflation; bag therapy; ozonated oil; intradiscal and paravertebral applications; in acupuncture points; minor autohemotherapy, and major autohemotherapy. The possibilities of clinical indications and dosages were also described, including immunological and infectious diseases. Although it is a minimally invasive and relatively safe approach, more clinical studies are necessary to standardize techniques, doses, and clinical indications.
Evaluation of the use of dry blood spots for progesterone determination in ewes
Authors: Melo Anyelle Maia , Silva Joziane Souza da , Claudio Jonatas Maciel , Amaral Rodrigo de Souza
Published: December 2022

The use of dried blood spots on filter paper has been shown to be a practical alternative in several studies with humans and animals, enabling a simple means of storing and transporting viable blood samples for various laboratory analyses. However, its applicability in the measurement of progesterone in animals is scarce. Thus, the objective of this study was to evaluate the feasibility of using dried blood spots for the measurement of progesterone in sheep. In total, 38 blood samples from 6 sheep were dripped onto filter paper, and the remainder of each sample was separated into serum. The progesterone levels in the serum samples and in the dry drops were measured by enzyme immunoassay and subsequently correlated. The levels of progesterone in the serum and dry spots showed a high correlation between the matrices (R2 = 0.9694). In conclusion, this study demonstrated the feasibility of using samples of dried sheep blood spots for the measurement of progesterone, and the storage and transport technique can be applied in the field.
The Rv2807 target gene: a determining factor to directly detect Mycobacterium bovis from suspected bovine tuberculosis lesions
Authors: Anjos Taís Ramalho dos , Sudária Maria Júlia , Castro Vinícius Silva , Figueiredo Eduardo Eustáquio de Souza , Carvalho Ricardo César Tavares
Published: December 2022

Bovine tuberculosis (bTB) is a zoonosis caused by Mycobacterium bovis, a species belonging to the Mycobacterium tuberculosis complex (MTC) group. Direct bTB diagnosis from suggestive lesions can be performed by nested q-PCR targeting the Rv2807 gene present in the MTC group, as well as the TbD1 gene, present in M. bovis. In this context, the aim of the present study was to assess the importance of considering positive MTC results for the Rv2807 target gene obtained through the nested real time polymerase chain reaction (nested q-PCR) applied to samples obtained directly from suspected bTB lesions. A total of 174 samples of suggestive bTB caseous lesions were obtained during cattle slaughter in slaughterhouses in the state of Mato Grosso, Brazil. DNA was extracted from the lesions and nested q-PCR was performed to detect both MTC and M. bovis. Both samples positive for the Rv2807 (41/174) and TbD1 (29/174) were submitted to bacterial culturing (23/41), and the DNA of the isolates (23) was extracted and submitted again to nested q-PCR. The Rv2807 gene (MTC) was previously amplified by nested q-PCR directly from the lesions, although the TbD1 gene specific for M. bovis was not amplified previously in four of the successfully isolated samples (4/23), only following isolation, and only the Rv2807 gene was amplified before and after isolation. In conclusion, the target gene Rv2807(MTC) exhibited higher positivity in the analyzed samples compared to the TbD1 gene (M. bovis).
Hyperadrenocorticism in a crab-eating fox (Cerdocyon thous) kept under human care
Authors: Farsette Anna Beathriz Nascimento , Dias Neto Ramiro das Neves , Barbosa Bruna Emely Pereira , Miranda Bernardo de Paula de , Alves Arthur Carlos Trindade , Barros Matheus de Almeida
Published: December 2022

Hyperadrenocorticism is a relatively common endocrine disease affecting the adrenal glands of domestic dogs. However, there are few reports of this disease in wild canids. A crab-eating fox (Cerdocyon thous) kept under human care was diagnosed with the disease after detection of conformational abnormalities in the adrenal glands visualized by ultrasonography, a cortisol suppression test after low-dose dexamethasone, and the detection of proteinuria and bacteria in urinalysis. After the diagnosis, the patient was treated with trilostane with a satisfactory clinical response. This report aims to report the sonographic and laboratory findings of hyperadrenocorticism and its treatment in a specimen of the species.
Tracheostomy-related Tracheal Tears in Pediatrics
Authors: Alenezi Mazyad , Alsudays Ali , Alanazy Sultan , Almashharawi Eman , Bawazir Samir
Published: December 2022

Introduction:

Tracheostomy-related tracheal tear is a serious complication that may follow surgical or percutaneous tracheostomy. Pediatric populations carry a higher risk because of anatomical differences. The aim of this article is to review this condition and to help in its diagnosis and management with the assistance of clinical and radiological findings.

Materials and Methods:

An English literature review was done using the terms pediatric, tracheostomy, tracheal tear and tracheostomy tube.

Result:

Two cases reported in the literature met the criteria to be included in the review.

Discussion:

Tracheostomy-related tracheal tear needs immediate diagnosis as it may lead to life-threatening outcomes, such as pneumothorax, respiratory distress, extensive subcutaneous emphysema and pneumomediastinum. Symptoms and complications of the tear may occur intraoperatively or postoperatively. Gold standard methods for diagnosis include flexible or rigid tracheobronchoscopy, which helps in determining the management plan. The treatment choices for iatrogenic tracheal tears depend on the tear site, size, and extension of the tear and patient’s hemodynamic status. Conservative management is sufficient for stable patients with small tears, whereas surgical management is essential for unstable patients and those with large or complicated tears.

Conclusion:

Tracheostomy-related tracheal tear is a serious rare complication. The pediatric age group carries a higher risk of the condition and its management, either conservative or surgical, depends on airway endoscopy findings and patient’s hemodynamic status.
Bibliometric and Semantic Analysis of the Global Research on Biomarkers in Personalized Medicine
Authors: Khakimova Aida , Rahim Fakher , Zolotarev Oleg
Published: December 2022

Aim:

The aims of the research were to study the citation history of popular articles in the field of biomarkers in personalized medicine, to study the use of terms in the sections of articles, and to consider the key terminology of the most-cited articles and its visualization.

Background:

The article describes approaches to the analysis of publication activity in the field of biomarkers and personalized medicine based on the data from the Web of Science.

Objective:

The aim of this study is a bibliometric and semantic analysis of the investigation field related to the application of biomarkers for the purposes of personalized medicine.

Methods:

The evaluation of a number of publications and its’ citations was carried out. The key terms extracted from the most-cited articles were divided into thematic groups. The number of citations of the most popular articles since 2011 was estimated.

Results:

The citation histories of the top ten articles were considered. Analysis of key terms from different parts of the most-cited articles included statistics and thematic ranking. The comparison of key terms from the most-cited article and the citing articles allowed us to show that the key terminology of the cited article extends to the citing articles. We presented the key terms of the most-cited articles as a terminological map.

Conclusion:

The study of citation of the articles in the field of personalized medicine and biomarkers was based on a survey on the Web of Science. Based on the analysis of a number of citations the trends and citation histories were constructed. The statistical and thematic analysis of the use of keywords in different sections of articles was done. We have shown that the citing articles spread the key terms of the cited article to identify trends in knowledge development which could be presented as a terminological map.

Others:

We presented the results in the form of a terminological map of the latest developments in the field of biomarkers in personalized medicine based on proposed principles.
Comprehensive Review on COVID-19 and Pregnancy
Authors: Chowdhury Selia , Bappy Mehedi Hasan , Chowdhury Samia , Chowdhury Md. Shahraj , Patel Vraj , Desai Shreeya , Fonseca Ayesha , Sekzer Catalina , Zahid Samina , Masenga Matias Juan
Published: December 2022

It is of greatest concern that how COVID-19 is affecting pregnancy, mothers, and babies. Scientists are studying the impact of COVID-19 on pregnant women and babies and understanding a little more every day. Reports show that there is an increased risk in pregnant women compared to nonpregnant women to get more serious illness due to COVID-19. Researchers are also investigating COVID-19 and its potential impact on a fetus, there are exceedingly rare cases of COVID-19 transmission to the fetus, and newborns can pick up COVID-19 when exposed. Vaccines are proved to be safe for pregnant women and help prevent both mother and the fetus from getting COVID-19. They are highly effective to prevent COVID-19 infection, critical sickness, and fatalities. There are specific guidelines for labor and delivery during the COVID-19 pandemic which are to be imposed and followed to achieve safer and healthier childbirth. In this article, the overall influence of COVID-19 in pregnancy, its pathophysiology, effects on placenta and neonates, maternal and perinatal features and outcomes, the role of vaccination, available treatment options, and the guidelines to be followed during the pandemic are discussed based on available research articles.
Higher Scores of Ambient Temperature, Sunshine Hours and UV Index are Associated with Lower COVID-19 Mortality
Authors: Errasfa Mourad
Published: December 2022

Background:

Following two years of the COVID-19 pandemic, thousands of deaths were registered around the world. A question on whether climate parameters in each country could or not affect coronavirus incidence and COVID-19 death toll is under debate.

Objective:

In this work, we aimed to analyse possible relation between the prevalence of COVID-19 deaths and the geographic latitude. The study focused on the geographic latitudes and some of their associated climate factors, such as the average annual level of temperature, sunshine hours and UV index.

Methods:

We sought the number of the deaths caused by COVID-19 in 39 countries. Latitude levels were plotted against the average annual levels of either temperature, sunshine hours or UV index. Data were analysed by simple linear regression or polynomial regression, by means of Microsoft Excel software (2016).

Results:

When COVID-19 death numbers were plotted against geographic latitudes, we obtained inverted bell-shaped curves, for both the first and second year of the pandemic, with a coefficient of determination of (R2 = 0,32) and (R2 = 0,39), respectively. In addition, COVID-19 death numbers were very negatively correlated with the average annual levels of temperature (R2 = 0,52, P= 4.92x10-7), sunshine hours (R2 = 0,36, P= 7.68x10-6) and UV index (R2 = 0,38, P= 4.16x10-5). Bell-shaped curves were obtained when latitude was plotted against the average annual number of temperature, sunshine hours and UV index, with a coefficient of determination of (R2 = 0,85), (R2 = 0,452) and (R2 = 0,87), respectively.

Conclusion:

In contrast to high-latitude countries, countries located at low latitudes may have suffered less COVID-19 death tolls, thanks to their elevated temperature, sunshine hours and UV index. The above climate factors, in addition to yet unknown factors, could have impaired the spread of the coronavirus and/or helped individual’s natural immunity to fight COVID-19 disease.
Nanocarriers For Drug Targeting
Authors: Gidwani Bina , Sahu Varsha , Namdeo Priya , Tiwari Sakshi , Tripathi Atul , Pandey Ravindra Kumar , Shankar Shukl Shiv , Joshi Veenu , Jain Vishal , Thareja Suresh , Vyas Amber
Published: December 2022

Drug targeting specific cells/tissues of the body without their becoming a
part of the systemic circulation is a prominent area of research in drug delivery, with
the main emphasis on improvement in formulation and development. Drug-targeting
can improve the viability, lower/minimize the adverse/side effects, and can become
cost-effective. Certain limitations like short circulating half-life, bioavailability issues,
rapid metabolism and degradation, poor tissue distribution and penetration in the
blood-brain barrier, intestinal absorption barriers, etc., are associated with the delivery
of various therapeutic agents. Nanocarriers have arisen in the field of drug targeting
with valuable delivery of drugs to site-specific/desired areas which is a significant
therapeutic advantage since it keeps drugs from being conveyed to some unacceptable
spots. Nanocarriers prevent the obstacles in clinical utilization of the therapeutic agents
as they decrease the serious and critical side/adverse effects by targeted drug delivery
and provide slow and sustained drug release. Nanocarriers bring new trust to drug
targeting by upgrading the efficacy, defeating resistance, and minimizing toxicity. This
chapter mainly focuses on the role and benefits of nanocarriers in drug-targeting and
nanocarriers as prominent systems for targeting and delivering drugs to achieve
maximum effects with improved therapeutic response.
Targeting Potential of Nanocarriers for Efficient Treatment of H. Pylori Infection
Authors: Jain Sunil K. , Rajpoot Kuldeep , Kesavan K. , Yadav Awesh , Gupta Umesh , Gupta Prem N.
Published: December 2022

Helicobacter pylori (H. pylori), a prevalent human-specific pathogen, plays
a key role in the development of peptic ulcer disease, gastric carcinoma, and gastric
mucosa associated lymphoid tissue lymphoma. Once infected, those bacteria reside
below the gastric mucosa adherent to the gastric epithelium, and entry of drugs to this
target site is very difficult. The bacteria can also acquire resistance to commonly used
antimicrobial drugs. Thus, an effective antimicrobial concentration cannot be achieved
in the gastric mucous layer or on the epithelial cell surfaces where H. pylori exist and
caused inefficient treatment. Such challenges have encouraged researchers into
developing some therapies based on nanotechnology.
Management of community-based Melasti beach tourism destinations
Authors: Wiartha Nyoman Gede Mas , Suda I Ketut , Dharmika Ida Bagus
Published: December 2022

Communities in a tourism destination have the potential for a variety of activities that can be created into attractive tourism products. Tourism destinations encourage the emergence of new trends towards community-based tourism development. Planning and developing tourism destinations so as to have opportunities for the community to get hopes, wishes from the development of existing tourism destinations in Ungasan Village, Badung Regency. Based on this phenomenon, there are three main problems in this study. First, why can Melasti Beach become a tourist destination in Ungasan Village, Badung Regency? How is the management of the community-based Melasti Beach tourist destination carried out with the relevant government in Badung Regency, Bali? These problems are studied with several theories, namely imperative functionalism theory, management theory. Management of community-based Melasti Beach Tourism Destinations in Ungasan Village, Badung Regency because Melasti Beach has beautiful beach tourism attractions, complete facilities and infrastructure, and there are institutions that regulate the course of tourism activities.
The Effect of the Covid-19 on the Purse Seine Fishing Business at CFP Bajomulyo, Pati
Authors:   Department of Capture Fisheries, Faculty of Fisheries and Marine Sciences, Diponegoro University, Ningtyas Dyah Rahayu , Suherman Agus , Mudzakir Abdul Kohar ,   Department of Capture Fisheries, Faculty of Fisheries and Marine Sciences, Diponegoro University
Published: December 2022

The COVID-19 virus has brought many changes in the economy and business, including in the CFP Bajomulyo, Juwana, and Pati Regency fishing businesses. This study aimed to determine the impact of the COVID-19 pandemic on capture fisheries business from a technical, marketing, social, and financial perspective on the fishing business using purse seine fishing gear at CFP Bajomulyo, Pati. The sampling method is the purposive sampling method with a total sample of 13 respondents. The results of the study show that technically and socially. There is no influence from the presence of COVID-19, while in financial and marketing aspects, there is an influence of COVID-19. The effect is an increase in fixed costs, variable costs, and total costs and income of small-scale fishing businesses, respectively, by 0.9%, 5.7%, 4.7%, and 1%. Meanwhile, for medium-scale businesses, there was an increase of 0.45%, 4.6%, 3.6%, and 2.8%. The profit for small-scale businesses increases by 1.81%, and for medium-scale businesses decreases by -0.35%. The NPV, IRR, R/C Ratio and PP values of each business have different results, but all of the values are positive, which means they include in the feasible business category. In terms of marketing, the impact of COVID19 is an increase in the price of fish such as scad (Decapterus sp) 1.5%, lemuru (Sardinella sp) 1.01%, tuna (Euthynnus affinis) 1.3%, banyar (Restrelliger sp) 1.15%, mackerel (Scomberomorini) 1.03%.
Fisheries Resource Management of Lake Tempe Based on Co-Management in Wajo Regency, Southern Sulawesi
Authors:   Manajemen Sumber Daya Perairan, Universitas Puangrimaggalatung, Sengkang, Kurniawan B Agus , Abbas MH ,   Administrasi Publik, Universitas Puangrimaggalatung, Sengkang, Asriani Asriani ,   Dinas Perikanan Kabupaten Barru, Ahirta Andi Dian ,   Aquaculture Sciences, Huazhong Agricultural University, Wuhan, China
Published: December 2022

One of the most important sectors in Wajo Regency, South Sulawesi is the fisheries sector. This sector contributes to regional income, food security, and job creation. Lake Tempe has several problems such as conflicts between fishermen, unrestricted access to new technology, inadequate management of fisheries resources, uncontrolled fishing, and traditional community-based fisheries management. Co-management is carried out to organize activities in fisheries management. For this reason, it is necessary to strengthen institutions in managing the use of fishery resources and developing networks between fishing communities. This research was conducted using a structured questionnaire to identify and integrate the co-management model in Lake Tempe. There are relevant findings regarding this research, some of which are: (1) Goals, (2) Targets, and (3) Strategies, namely infrastructure strategy, banking services, coordination between authorities, organizational structure, cooperation, formation of cooperatives, training programs, and utilizing local wisdom. Natural resource management is a form of adaptive management, co-management, and change governance. Stakeholder involvement in improving conservation management and taking socio-economic aspects of the characteristics of the Tempe Lake area is an important element in efforts to design and implement co-management in fisheries resource management.
The impact of COVID-19 vaccination coverage on reducing disease burden: A data-driven analysis comparing higher income and lower income countries
Authors:   Department of Mathematics, College of Science and Arts, King Abdulaziz University, Rabigh, Saudi Arabia, Hussien Hamid H.
Published: December 2022

COVID-19 (coronavirus disease 2019) vaccination remains a key preventive measure against the current pandemic. As of March 25, 2022, the World Health Organization (WHO) reported 476,374,234 confirmed cases of COVID-19 and more than six million deaths globally. Our motivation in this study was to examine differences in COVID-19 burden between countries (in terms of incidence and mortality), with the goal of answering whether countries with different income levels have different proportions of fully vaccinated individuals per 100,000 populations, whether this results in differences (on average) in COVID-19-specific incidence, mortality, and vaccination coverage, and whether vaccinations reduce the rate of infections and deaths caused by COVID-19. We performed simple one-way ANOVA (analysis of variance) tests as well as Spearman rank correlation analyses. Our results demonstrated that COVID-19 vaccination rates were low in low-income countries (LICs) and lower-middle-income countries (LMICs), and that the rates of recorded cases and deaths were the lowest in these countries as well (almost certainly due to low surveillance rates). In contrast, COVID-19 vaccination rates were high in high-income countries (HICs) and upper-middle-income countries (UMICs), and these countries also showed the highest rates of recorded cases and deaths. The country-level proportion of people receiving COVID-19 vaccines was statistically significantly and negatively correlated with COVID-19 descriptives in HICs and showed negative weak-to-moderate correlations in lower and middle-income countries. However, there is no proof that this association is causative in nature. Our findings inform research directions, policy initiatives, and medical guidelines.
Evaluation of Phytochemical Properties and Biological Activities of Leaf Extracts and Oil of Petroselinum sativum Collected from Algeria
Authors: Benmekhbi Lotfi , Mosbah Salima , Laamraoui Hanane , Hamlaoui Ikram , Bencheriet Serhouda , Ibrahim Demirtas
Published: December 2022

Indigenous medical professionals prescribe plant-based therapeutics for the handling of a range of maladies and use typical medical care at the preventive level. Oxidative stress, obesity, and multidrug resistance to pathogenic microorganisms are major challenges in the healthcare systems and pharmaceutical industries. This study aimed to screen phytoconstituents, estimate total phenol and flavonoid contents, and evaluate the antioxidant, and antimicrobial activities of Petroselinum sativum extracts and essential oil growing in Algeria. The antioxidant capacity of n-butanol, dichloromethane extracts and essential oil was determined by using DPPH radical scavenging method. All extracts were also evaluated against Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacterial species using the disk diffusion method. The leaves are pharmacologically active and related to the detected phytochemical components. In the proximate analysis, plant nutrients that are important for diverse pharmacological activities are found in the leaves. The ethyl acetate extract of P. sativum showed the highest phenol content while the n-butanol and ethyl acetate extracts gave high flavonoid contents at 144.44 ± 0.07 and 100.97 ± 0.04 mg/g, respectively. The antioxidant results demonstrate powerful free radical scavenging activity for three extracts. The activity reduced in the following order as concentration increased n-BuOH > AE > DCM.
Biodecolorization of Methylene Blue by Using Bacillus subtilis Immobilized into SA-PVA-Bentonite Matrix in Mineral Salt Medium and Non-nutritious Medium
Authors: Rohmah Alya Awinatul , Purnomo Adi Setyo , Safitri Widiya Nur
Published: December 2022

Industrial dye wastewater can potentially cause significant harm to organisms and the environment across the world. Methylene blue (MB) is a synthetic dye that can be found in wastewater. Immobilizing clay material and degradative bacteria into a carrier is the best way to remove MB. Therefore, this study aimed to immobilize Bacillus subtilis in sodium alginate (SA)-polyvinyl alcohol (PVA)-Bentonite for adsorption and degrading MB in nutritious mineral salt medium (MSM) and non-nutritious media. The result showed that SA-PVA-Bentonite-non-living B. subtilis beads (SPB-nBS) had the highest result in non-nutritious medium, approximately 88.89%. While in nutritious MSM, living B. subtilis addition into beads (SPB-BS) reached the highest MB removal, which was 94.31%. Nutritious MSM had a role as the sole carbon and energy for living B. subtilis. So, it could adsorb and degrade MB by its enzymatic system. The degradation products were predicted as C7H10N2O4S, C8H10N2O2 and C6H8N2O3S. Hence, this study indicated that a nutritious medium was the suitable medium for MB degradation. According to the SEM result, the bacteria spread and covered the beads. Furthermore, the adsorption kinetics and isotherms were also analyzed; SPB beads followed the pseudo-second order kinetic model and Langmuir isotherm.
Application of Numerical Nonlinear Optimization Problems
Authors: Pattar Dr. Raveendra Tammanna
Published: December 2022

Abstract: In this paper develops a method based on fuzzy logic for solving linear approximation relationship nonlinear optimization problems. In the proposed method, the nonlinear objective function as well as the constrained functions forming the feasible regions is linearly approximated about an initial feasible point by Taylors Series and then the nonlinear optimization problem is approximated to a linear optimization problem or a linear programming problem. The concept of fuzzy decision making is iteratively applied to find the fuzzy optimal solution of the problem.
Toxic Effects of Fungicide Sheathmar to Worm, Tubifex Tubifex
Authors: Medda Sharmistha , Saha Nimai Chandra , Bhattacharya Ritwick , Chatterjee Arnab , Ghosh Shruti , Pal Sarmila
Published: December 2022

Abstract: The current study sought to determine Sheathmar's acute toxicity as well as its sublethal effects on oxidative stress enzymes in Tubifex tubifex, a benthic oligochaete worm. The results showed that the 96-hour median lethal concentration (LC50) of Sheathmar for Tubifex tubifex is 3186.3 µg/l. According to the model fit performance, the GUTS-SD model can better predict the survival rate of Tubifex tubifex. Sublethal Sheathmar concentrations (10% and 20% of the 96h LC50) significantly changed the oxidative stress enzymes. Reduced glutathione (GSH), glutathione S-transferase (GST), and glutathione peroxidase (GPx) activity all showed a significant initial increase followed by a decline, whereas catalase (CAT) activity and malondialdehyde (MDA) levels increased significantly with increasing Sheathmar concentrations at all exposure times. Furthermore, the effects of Sheathmar on Tubifex tubifex were demonstrated by the development of a potency index and the assessment of integrated biomarker response (IBR). These findings suggest that exposure to Sheathmar influences Tubifex tubifex survival at the acute stage and modifies oxidative stress enzyme alterations at the sublethal level
Study and Analysis of Effective Traffic Management on Porwal Road
Authors: Dongre Harshada S. , Raskar Rohit R. , Lengare Atul , Jaiswal Mayur , Ingle Prof. Dr. Aakanksha
Published: December 2022

Abstract: In many contemporary cities around the world, traffic congestion is a serious issue. In the biggest and most crowded cities, traffic congestion has been a major source of issues and concerns. For those who must commute in traffic, getting about the city is becoming increasingly challenging. Because of the congestion issues cause individuals to waste time, pass on opportunities, and become irritated. Due to the ambulance's position in a traffic jam, there is a potential that someone could pass away inside of it. Damage to life and property could result if the fire department is unable to arrive in time. The companies are directly impacted by the traffic congestion. Due to traffic jams, workers are less productive, trade opportunities are lost, deliveries are delayed, and as a result
A Project Report on Planning, Scheduling, and Delay Analysis of a Construction Project during Covid-19 Pandemic: A Case Study
Authors: Sasane Prathamesh Y
Published: December 2022

Abstract: Time delay is one of the biggest problems faced by the construction industry in India. Completing projects on time isthe key factor of the project, but the construction process is subject to many variables and unpredictable factors, which result from many sources such as the availability of resources, external factors, the performance of parties, and the type the structure. Delay in the project, leadsto loss of productivity,increased cost, contract termination, and disputes between contractor and owner. These types of unrealistic exceptions are usually avoided by using a clean and efficient planning mechanism, which specifies the work and timetable to be used.This project aims to examine the causes and effects of delay ona building construction project during the construction phase and to provide control measures for time overrun in the project. A study was carried out on construction schedule, delays an,d various delay analysis techniques and methods to evaluate the causes of delay and their impacts on the construction project. The current study is based on a residential building, “Savali Saffron” located at Mundhwa, Keshav Nagar, near the old Orbis School, Pune, developed by Sapthasiddhi Associates. Studyingthe A-Wing, during the COVID-19 Pandemic, a delay of 42 days has been observed, with a sum of RS 8,26,500/- added to the original budget of the construction project. The effect of the COVID-19 Pandemic on Constructiontion Project is studied.
Comparative Study of Conventional Concrete and Green Concrete Made Of Fly Ash, Recycled Red Bricks and Recycled Crushed Aggregates
Authors: Shahroz Malik Mohammed , Chandra Mrs. B. Sahithi
Published: December 2022

Abstract: Because cement is a binding substance, it is commonly utilized in building. Cement production accounts for 8-10% of total world CO2 emissions.. This greenhouse gas is produced when lime stone and clay are smashed and heated to high temps in mills. Concrete contributes significantly to greenhouse gas emissions and complicates waste disposal. Therefore the use of recycled materials in concrete has become necessary. A Danish scientist by the name of Dr. WG made the initial discovery of green concrete in 1998, which has been a groundbreaking idea in the history of concrete. The term "green concrete" refers to a type of concrete that includes recycled components that are environmentally friendly, has greater performance, and have a longer life cycle .By utilizing industrial ecology, green chemistry, as well as the structural behaviour and organisation of cement nano-particles in the mix for higher performance, researchers have made numerous attempts to find alternatives that can significantly reduce high energy consumption and environmental impacts during the fabrication process of cement. It is also Observed that the increase in RHA to 20% i.e (Mix 2) & not changing the other two components, leads to the decrease in the strength, this is because of much replacement of Materials which effects the binding Factor of Cement & Aggregates. The Main Advantage of RHA replacement by 10% shows high strength growth by 33% when compared to conventional Concrete on 28th Day. In this assignment, we'll conduct tests on both freshly laid concrete and hardened concrete, including a compressive strength test. In this project, the typical components of concrete, such as F.A. and C.A., are substituted by powdered clay brick and crushed glass waste, respectively. Cement is also partially replaced with rice husk ash. M20 is the concrete grade that was employed