bluuebunny/crossref_metadata_2025 huggingface dataset:
Biogenic synthesized selenium nanoparticles combined chitosan nanoparticles controlled lung cancer growth via ROS generation and mitochondrial damage pathway
Authors: Mahmood Rana I. , Al-Taie Alaa , Al-Rahim Aya M. , Mohammed-Salih Harraa S. , Ibrahim Humam Abdulrahman , Albukhaty Salim , Jawad Sabrean F. , Jabir Majid S. , Salem Mohamed M. , Bekhit Mounir M.
Published: February 2025

The green synthesis approach has drawn a lot of interest as an environmentally friendly and sustainable acceptable means of producing a diverse range of nanoparticles (NPs). This piece described a rapid approach for synthesizing selenium nanoparticles (SeNPs) with grape seed extract. A biologically active composition of selenium-chitosan nanoparticles (Se-chitosan NPs) has been prepared and characterized using, ultraviolet–visible, scanning electron microscopy, transmission electron microscopy, and zeta potential and size distribution experiments. To study the anticancer activity of prepared NP cytotoxicity (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay of chitosan nanoparticles (Chito-NPs), SeNPs were tested on two cancer cell lines: A549 and normal cell line (HK-2). In addition to a series of morphological changes, induction of apoptosis, reactive oxygen species (ROS) generation, and mitochondrial membrane potential. The results showed that the synthesized NPs were spherical with 55.285 and 30.9 nm, for SeNPs and Se-chitosan NPs, respectively. In the A549 cell line, SeNPs and Se-chitosan NPs exhibited dose-dependent cytotoxicity, with an IC50 for Chito-NPs of 24.09 µg/mL, whereas for SeNPs it was 18.56 µg/mL. Conversely, normal cell lines (MCF-10) were not significantly cytotoxically affected by SeNPs and Se-chitosan NPs. Additionally, SeNP and Se-chitosan NP treatment resulted in increased ROS generation and caused mitochondrial dysfunction. Based on ROS-mediated pathways, the results demonstrated that Chito-NPs, SeNPs, and Se-chitosan NPs cause apoptosis and death in A549 cells. As nanotherapeutics, Chito-NPs, SeNPs, and Se-chitosan NPs appear to offer a great deal of unrealized potential based on these findings. Further investigation is warranted and clinically significant to elucidate the specific therapeutic potential and safety of these NPs when applied in vivo. In this work, we show that exposure to SeNPs, Chito-NPs, and Se-chitosan NPs alters the human lung cancer cell line A549’s ROS route of signaling, thereby causing the induction of apoptosis.
Waste Around Longhouses: Taphonomy on LBK Settlement in Hlízov
Authors: Pilař Daniel , Denis Solène , Pavlů Ivan
Published: February 2025

The research investigates the waste management and taphonomy of a Linear Pottery Culture (c. 5600–4900 BC) settlements. Waste deposition significantly shaped the archaeological record of the Early Neolithic in Central Europe and its reconstruction fundamentally influences our perception of the settlement space and the daily life of Neolithic people. Traditionally, it has been assumed that individual households discarded waste near their longhouses. However, findings from the site Hlízov (Czech Republic) reveal a more complex waste management system, with designated disposal areas and differential treatment of various waste types. Additionally, two overlapping waste distribution networks were identified, indicating distinct models of production and waste management organisation. These settlement-wide networks were discovered due to the abandonment of the rigidly used house unit model, which appears to be inadequate for this site.
Technically Getting Off: On the Hope, Disgust, and Time of Robo-Erotics
Authors: McNealis Rachel
Published: February 2025

As robots evolve from functional machines to potential sexual companions, they embody both utopian hopes and dystopian fears. This article explores the ethical implications of sex robots, focusing on power dynamics, objectification, and gender performance. Through Ann Cahill’s concept of derivatization, the article argues for a nuanced understanding of sexual objectification in the context of robo-erotics. While sex robots offer new possibilities for intimacy and desire, they also risk reinforcing problematic gender norms and power structures. The article introduces a queer utopian framework, oscillating between hope and disgust, to examine how sex robots might subvert or perpetuate traditional scripts of sexuality. Ultimately, this work aims to situate sex robots within the broader landscape of technological advancement and its potential to reshape human sexuality.
Dicen que en el punto medio está la virtud. El cambio de ideología de Mariano Barreto a través de Idioma y letras (1904)
Authors: MARTÍN CUADRADO CARMEN
Published: February 2025

Este artículo tiene como finalidad principal analizar el cambio ideológico que Mariano Barreto proyecta en su repertorio Idioma y letras (1904). El autor, perteneciente a la corriente purista en un primer momento, va modificando progresivamente sus concepciones acerca de la lengua hablada en Nicaragua, e incluso valora positivamente ciertos aspectos de su variedad. Tras presentar la figura del autor y el contexto en el que publica su obra, se analizan tanto las páginas preliminares como el interior del cuerpo del texto con el objetivo de identificar cuáles son las actitudes lingüísticas del autor en un momento histórico relevante para la construcción del español centroamericano.
Moderate Earthquakes of Korçë — Leskovik Seismogenic Zone in Albania During This Century
Authors: Rrezart Bozo , Rrapo Ormeni , Erald Silo , Donald Mucaj , Ismail Hoxha , Petraq Naco , Dashamir Gega , Olgert Gjuzi
Published: February 2025

Abstract: Albania is situated in Alpine-Mediterranean seismic belt comprising the zone of contact between lithosphere plates of Africa and Eurasia. The main cause of Albanian seismicity is the collision of Adria microplate with the Albanian orogeny. Albanian territory is characterized with high level of seismic hazard in the Europe. The earthquakes foci are concentrated mostly along the active faults and low velocity zones. In this century, seismic activity in the Leskovik-Korça-Ohrid (LKO) fault zone has been dominated by seven moderate earthquakes, with magnitudes (ML) ranging from 4.5 to 5.3. Additionally, in the Leskovik-Korça-Ohrid region, there have been approximately 30 earthquakes with ML ≥ 4.0, and 7 earthquakes with ML ≥ 4.5, including 4 earthquakes with ML ≥ 5.0. A series of earthquakes, including the maximum magnitude event (ML = 5.3), began on June 1, 2019, at 04:26 (UTC) near Floq village, about 17 km southwest of Korça, highlighting the increased seismic activity in the Leskovik-Korça-Ohrid seismogenic zone. The focal mechanism analysis reveals that in southeastern Albania, the dominant faulting type is normal faulting with a strike-slip component. This faulting occurs in the direction of N to S extension and is associated with the convergence between the Adriatic microplate and the Albanian orogen. The focal mechanisms solution of 8 moderate earthquakes during this century indicate that the extensional regime was the main cause of the seismic activity along the inner Albanides. This study presents an analysis of the focal mechanisms of seismic events. Together with the strongest earthquake, which occurred in May 1960 (M = 6.2), this activity forms a roughly N–S trending active seismotectonic zone in southeastern Albania, posing a significant seismic threat to nearby urban areas in Albania, Greece, and North Macedonia.
Soil Descompactor Equipment for Deep Tillage
Authors: Chávez Marco Antonio Reynolds , Lezama Rigoberto Zetina , Burela Ángel Capetillo , López Juan Antonio López , López Gilbert Fresh López
Published: February 2025

Abstract: Soil preparation is definitely one of the most critical and costly agricultural activities for the establishment and subsequent
development of crops in any production system. The importance is based on preserving the planting site in conditions that are favourable
for crop yields. At present in our country, conventional tillage with disc plows is mostly used for primary or deep tillage of the soil,
which shows the urgent need for the development of technologies to reduce the loss and degradation of this invaluable resource. The
search for solutions to this problem in soil preparation has led to the study and adoption of conservation tillage practices, including
vertical tillage (VT), in order to reduce the impact on the environment and especially on soil resources. It is convenient to point out
that the VT is a conservation tillage alternative that promotes energy saving and improves physical properties compared to conventional tillage. The objective of the present work was to develop a prototype of a mechanical implement to remove hard soil layers, using the parameters of vertical tillage and the critical depth theory; capable of reducing fuel consumption and effective tillage time by up to 50%, in addition to improving the quality of tillage and some physical parameters of the soil compared to conventional tillage applied with disc plow. The results show the development of a prototype for deep tillage that removes hard soil layers. This equipment uses a plow with five rigid chisels with narrow tips and the combined effect of design and operating parameters. This deep tillage implement does not invert the soil and subsequently requires a harrow cross pass. Likewise, this technology represents savings in fuel consumption and effective operating time of up to 50% per hectare depending on site conditions.
«Vieja barbuda, de lejos la saluda»: la vejez en femenino al prisma de los textos doctrinales de la España de la temprana Edad Moderna
Authors: Orobitg Christine
Published: February 2025

El propósito de la presente contribución es estudiar las representaciones de la mujer mayor en los textos doctrinales, principalmente médicos y demonológicos de la España de la temprana Edad Moderna. La visión peyorativa de la mujer mayor encuentra su base en los saberes médicos, que definen el temperamento femenino como imperfecto, en la frialdad femenina, que se refuerza con la edad y en los mecanismos de producción, circulación y evacuación (o no evacuación) de la sangre menstrual. El articulo analiza los mecanismos conceptuales mediante los cuales estos criterios motivan un rico y denso imaginario en que la mujer mayor es representada como como un ser maligno y tóxico, en relación estrecha con las doctrinas sobre la fascinatio.
La anciana transformada en bruja por la tradición demonológica
Authors: Ortiz Alberto
Published: February 2025

Uno de los estereotipos creados al interior del mito de la brujería representa a la mujer anciana como una sirvienta de los demonios. Tras la imagen común, diseñada por los tratados demonológicos desde la élite intelectual cristiana, voz dictaminadora y censora y descriptora de los personajes principales, pueden vislumbrarse los prejuicios y temores de una cultura que pretende regir la conducta moral de sus individuos. Sin embargo, una somera revisión de los grabados y opiniones principales de los libros más representativos del género demostraría que la descripción no se estanca en el cliché popular, sino que abarca más aspectos esenciales para comprender el tipo de ideología que la sustenta, por ejemplo: el diseño de la víctima propicia, la prohibición tácita del conocimiento, y la funcionalidad femenina ideal.
La persecución inquisitorial contra la matriarca criptojudía
Authors: Perez Villanueva Sonia
Published: February 2025

La persecución inquisitorial de las mujeres criptojudías tuvo importantes contradicciones, particularmente las que se manifiestan en la narrativa e iconografía de la propaganda encargada por la Inquisición. Las mujeres judías representadas en el imaginario católico son típicamente jóvenes, hermosas y sensuales, y contienen un mensaje didáctico de perversión. La representación de las mujeres judías como hermosas, pero peligrosas, sigue una tradición cristiana que se basa en un patrón de marcas peyorativas. Estas imágenes reflejan mujeres sensuales, vestidas con ropas lujosas, adornadas con joyas sobrecargadas, que seducen y engañan a los hombres católicos, quienes se ven incapaces de rechazar su belleza y caen en su seducción. El elemento propagandístico de las obras es didáctico ya que advierten a la audiencia católica masculina de que la juventud y la belleza son únicamente una estrategia de tentación, y que toda mujer judía joven y bella, llegará a ser, eventualmente, una judía vieja, representación del mal y del pecado. Lucía González, anciana de 70 años, acusada de judaizante relapsa y última víctima mortal de la Inquisición en 1738, representa esta persecución. El personaje anciano simboliza la imagen inquisitorial estereotipada de la mujer judía matriarcal, quien se mantiene activa en su sacrilegio contra Cristo y, como alegoría de la sinagoga, se convierte en la propia personificación del judaísmo.
Sobre la composición de «La manganilla de Melilla»: una propuesta de datación
Authors: Resta Ilaria
Published: February 2025

La datación del repertorio alarconiano sigue representando un reto para todo estudioso que se acerque a su dramaturgia. En este trabajo abordaremos la cronología de composición de La manganilla de Melilla, publicada en 1634 en la Parte segunda de las comedias de Ruiz de Alarcón. A partir de una serie de datos textuales, documentales, métricos y estilométricos, se avanzará una nueva propuesta cronológica para la pieza, distinta de la hipótesis que la crítica ha venido defendiendo hasta ahora acerca de una composición que se remontaría a la primera fase de la producción de este dramaturgo novohispano.
Rechazo de los tratamientos médicos: el tópcio «de medicina contempta» en diálogos humanistas
Authors: Sánchez Manzano María Asunción
Published: February 2025

El primer objetivo de este trabajo es la recepción del desprecio de la medicina (Plinio, Plutarco) en el ambiente universitario castellano como tópico de algunos diálogos. En segundo lugar, nos fijamos en el traslado de los recursos relativos a este tópico, desde una disputa y una quaestio hasta su refutación en un comentario bíblico humanista.
La sabiduría de los griegos en la segunda parte de la «Monarquía Mística» de Lorenzo de Zamora
Authors: Seoane Rodríguez Manuel Andrés
Published: February 2025

La segunda parte de la Monarquía mística de Lorenzo de Zamora se inicia con una argumentación sobre la conocida sentencia apolínea del conócete a ti mismo en consonancia con un versículo bíblico extraído del libro de Job. El esfuerzo del humanista se concentra en la elaboración de un mosaico de citas y referencias de los Siete Sabios y filósofos y eruditos griegos, procedentes sin duda de fuentes intermedias que, por un lado, apuntalan esta coincidencia y, por otro, demuestran la antigüedad y prevalencia del precepto bíblico en tanto que verdad revelada
Palimpsestos del «Tiempo de regocijo y carnestolendas de Madrid» de Alonso del Castillo Solózano en el marco del «Honesto y entretenido sarao» de María de Zayas
Authors: Bonilla Cerezo Rafael
Published: February 2025

Este artículo informa de los palimpsestos del Decamerón (1353) de Boccaccio, la traducción por Francisco Truchado (1578) de las Piacevoli notti de Straparola (1550-1553), las cuatro Novelas a Marcia Leonarda (1621-1624) de Lope y, sobre todo, el Tiempo de regocijo y carnestolendas de Madrid (1627) de Alonso de Castillo Solórzano en el marco del Honesto y entretenido sarao (1637-1647) de María de Zayas. Se sondean los motivos de las fiebres cuartanas, los braseros, los dos estrados de la protagonista y el cromatismo de los trajes y faldellines.
Rojas Zorrilla en la fragua colaboradora: el autógrafo de «La más hidalga hermosura»
Authors: Rodríguez Nicolás Sergio
Published: February 2025

Este análisis del autógrafo de Francisco de Rojas Zorrilla de la segunda jornada de La más hidalga hermosura (escrita en colaboración por Juan de Zabaleta, Rojas Zorrilla y Pedro Calderón de la Barca) se une a los estudios de autógrafos teatrales auriseculares de las últimas décadas, intentando aportar su grano de arena en una mejor comprensión del proceso de escritura, autocorrección, censura y adaptación escénica por el que pasaban las comedias en el siglo xvii. En lo concerniente a la figura de Rojas Zorrilla, se comprueba cómo el dramaturgo toledano, a pesar de no ser tan minucioso como Calderón (solo hay que confrontar la tercera jornada de la propia La más hidalga hermosura), sí sometía sus textos a una cuidadosa revisión final antes de desprenderse de ellos y de que llegaran a manos de las compañías teatrales.
Relationship between timber grade and local, global, and dynamic modulus of elasticity in red oak and red maple structural lumber
Authors: Bencsik Balazs , Denes Levente , Hassler Curt C. , Norris Jonathan R. , McNeel Joseph F.
Published: February 2025

The modulus of elasticity (MOE) of structurally graded one-inch-thick red oak (Quercus rubra) and red maple (Acer rubrum) lumber was measured in this work. The center-point, third-point static loading tests, and the stress wave timer methods were used. The objective was to determine if there are statistical differences between three structural lumber grades based on their MOE values. The study considered both the within separated grades and the across combined grades. For red oak and red maple, significant differences in MOE values from center-point static loading tests were observed solely between Select Structural and Below-grade lumber. With the dynamic method, no significant differences were found between any visual grades, including Below-grade lumber. Regardless of the MOE determination method used, the MOE value was not useful for distinguishing the structural, No. 2, and No. 3 visual grades. The strongest correlation existed between the global MOE and the dynamic MOE, which was even higher when the analyses were conducted on separated visual grades. In the case of red maple, stronger correlations between the dynamic MOE, local MOE, and global MOE were observed when separated by visual classes, compared to the analysis conducted on the combined grades. The global MOE was found to be a better predictor of the local MOE than the dynamic MOE.
Andrographis paniculata mediated AuNPs as anti-microbial, antioxidant, anti-diabetic agents and their efficacy in wound healing of mice
Authors: Wu Can , Huang Liang
Published: February 2025

Gold nanoparticles (AuNPs) are known to have low toxicity and biocompatibility. Meanwhile, Andrographis paniculata (A. paniculata) is a medicinal plant known for its therapeutic benefits. Traditional methods for the synthesis of AuNPs frequently depend on toxic compounds, which present environmental and health hazards. In this work, A. paniculata was combined with AuNPs to enhance its antimicrobial, antioxidant, and wound healing effects, thereby offering a safer and more effective alternative compared to current available methods. Water-soluble gold metal ions were reduced to neutral metal nanoparticles in the course of reaction with aqueous A. paniculata extract. The biosynthesised AuNPs was examined using UV-Vis, FTIR Spectroscopy, TEM, XRD, SAED Diffraction, EDX, DLS, and zeta potential measurements. AuNPs were incorporated into nonionic surfactant to form a thick, readily spreadable hydrogel. The mixture was found to enhance the wound contraction rate with no skin irritation observed in treated mice. The study demonstrated a simple and environmentally safe approach to produce AuNPs with improved antimicrobial, antioxidant, antidiabetic and wound healing abilities. The AuNPs-PF127 hydrogel is a non-toxic and bio-friendly delivery technology that shows potential in promoting healing of wounds, burns, etc.
Children’s preferences for the styling of consultation room furniture based on scenic beauty estimation and Kansei engineering,
Authors: Hao Kangqing , Guan Huiyuan
Published: February 2025

Children’s preferences for the design of consultation room furniture were evaluated with a focus on the emotional and aesthetic factors influencing these preferences. An evaluation model for children’s furniture in consultation rooms was developed using the Scenic Beauty Estimation (SBE) method and Kansei Engineering. Data were collected by gathering children’s aesthetic ratings and emotional assessments of furniture sample images, followed by statistical analysis to identify design preferences on both visual and emotional levels. The SBE results revealed a negative correlation between straight-line desks, backrest-free designs, and square seat surfaces with scenic beauty, suggesting that children prefer furniture with soft, rounded shapes. The Kansei Engineering results identified two principal factors influencing children’s preferences, further highlighting that soft, rounded forms, lightweight and comfortable experiences, and minimalist designs significantly enhance emotional engagement and attraction. The consistency between the two evaluation methods was high. In conclusion, furniture design for children’s consultation rooms should prioritize safety, comfort, and playfulness, incorporating soft, simple, and child-friendly designs to enhance children’s acceptance and comfort within the examination environment.
Antimicrobial with time-kill kinetics, antioxidant, and anticancer properties of Rosmarinus officinalis L. oil extract based on its bioactive components
Authors: Abada Emad , Mashlawi Abadi M. , Gadallah Abdelalim A. , Hakami Othman , El Alfy Mervat A. Ahmed , Meganid Abeer S. , Elbaz Reham M.
Published: February 2025

There is a major clinical problem associated with antimicrobial resistance. Rosmarinus officinalis L. is an effective medicinal source. Its oil has been extracted and tested for its multiple therapeutic capabilities. The oil extract was found to be a broad-spectrum antimicrobial agent against Bacillus subtilis and Staphylococcus aureus as Gram-positive bacteria, Escherichia coli and Klebsiella pneumonia as Gram-negative bacteria, and Candida albicans as the most common pathogenic mold. The minimum inhibitory concentration of the oil extract was found to be 15.6 μg/mL against B. subtilis, S. aureus, and C. albicans, and 62.5 μg/mL and 125 μg/mL against E. coli and K. pneumonia, respectively. The bactericidal activity started at 150 and 180 min against Gram-positive and Gram-negative bacteria, respectively, with clear time-killing kinetics. The oil extract was able to scavenge DPPH free radicals with an IC50 of 4.0 μg/mL. The oil extract was found to have high toxicity on the Caco2 cell line (colon tissue) at high dose 1000 μg/mL with IC50 of 75.39 ± 0.56 μg/mL. The chemical composition of the oil extract was determined employing gas chromatography/mass spectrometry, in which 53 compounds were named at different surface area ratios, retention times, and probability ratios.
Der Österreichische Staatsrat - Protokolle des Vollzugsausschusses, des Staatsrates und des Geschäftsführenden Staatsratsdirektoriums 21. Oktober 1918 bis 14. März 1919, Band 3 13. Dezember 1918 bis 11. März 1919
Authors: Semotan Stefan
Published: February 2025

The third and final volume of minutes of the Austrian State Council (Staatsrat) encompasses the protocols of 13 December 1918 to 11 March 1919. In this phase the Staatsrat still faced the challenge of laying the groundwork for a republican order against the backdrop of severe supply shortages. Another concern was finding a basis for the relationship to the other successor states of the Habsburg Monarchy. These intertwined matters of domestic and foreign policy shaped the broad thematic spectrum of the minutes in this period. The volume hence makes an important contribution to the understanding of the transition period from the Austro-Hungarian Monarchy to the Austrian Republic.
Škorpion by Josip Kulundžić in the context of Croatian expressionism
Authors: Vuco Jurica
Published: February 2025

The paper Škorpion by Josip Kulundžić in the context of Croatian expressionism will present a dramatic text Škorpion in the context of Croatian expressionism. Along with the dramatic text Ponoć, it is considered to be Kulundžić’s most significant dramatic work in terms of aesthetics and quality. Škorpion witnesses a strong expressionist genre and stylistic dramatic determination, while on the other hand it continues to implement the author’s, also specific, expressionist poetic framework. An overview of the most important features and characteristics of Croatian expressionism, the origin and duration of expressionist poetics within the corpus of Croatian literature, and the fundamental characteristics and basic elements of Croatian dramatic expressionism will be presented. Expressionist poetics dominated Croatian literary creativity until the mid-twen-ties of the 20th century and remained present until the end of that decade and in that period Josip Kulundžić was the most fruitfull expressionistic writer. The paper will provide a brief overview of the poetic principles of dramatic writing of Josip Kulundžić as well as the most important principles of his second phase of expressionist production.

His second phase begins in 1926 with the dramatic text Škorpion which symbolizes the transition from his first to the second phase of his expressionist dramatic work. In this phase of the author’s work, expression-istic features are still dominant, but they begin to intertwine in places with realistic, sometimes naturalistic dramatic properties and psychological, social and existential dramatic signals that will characterize later drama. On the level of dramatic expression and content, expressionist features still stand out, but they are no longer so extreme and radical, and the concept of original, German dramatic expressionism replaces the view of Croatian dramatic expressionism and its already mentioned, specific features that will be present in all Croatian expressionist dramatists of the third decade of the 20th century. In the second phase of his expressionist dramatic creation, his plays will increasingly take on the characteristics of national literary and theatrical expressionism, thus securing Kulundžić’s position as one of the most prominent and prolific expressionist playwrights of Croatian expressionism. The paper will present typical and paradigmatic expressionist features in all segments of the dramatic text, from the plan of expression through stylistic features to the content part of the text. Also, the paper will present the characteristics of typical expressionist characters with an emphasis on the main character, the expressionist ironic anti-hero.
Andrew Snyder. 2023. Critical Brass: Street Carnival and Musical Activism in Olympic Rio De Janeiro
Authors: Müller Carolin
Published: February 2025

Andrew Snyder. 2023. Critical Brass: Street Carnival and Musical Activism in Olympic Rio De Janeiro. Middletown, CT: Wesleyan University Press. 320 pp. ISBN 9780819500199 (pbk).
Socialtjänsten som kunskapande praktik: Exemplet individbaserad systematisk uppföljning i öppenvården för barn och familj
Authors:   , Höglund Petra
Published: February 2025

The overall aim of this licentiate thesis is to explore what individual-based systematic follow-up of interventions (ISF) in social services means as a knowledge-producing practice. Based on the premise that knowledge is created through processes of creation and re-creation in practice, the study analyzes how these processes are expressed within the ISF practice. Conducted as a case study, it examines ISF in two cases of non-institutional social services for children and families in two Swedish municipalities, using different models for ISF: LOKE (Local Evidence) and FIT (FeedbackInformed Treatment). Empirical material was collected through interviews, observations, and documents.

The first article reveals how ISF results are transformed into knowledge when family therapists reflect on the significance of the results. Central to these reflections is the frequent relation of ISF results to the family therapists’ daily work, making the knowledge meaningful for them. The results also highlight the importance of facilitating opportunities for reflection within the ISF practice.

The second article examines how ISF is used within and by the organizations. The results show a multifaceted use of both ISU results, and the knowledge derived from them, as well as the ISF models themselves. The results also indicate that the impact of knowledge is often “creeping” and occurs over time, integrating with other information, knowledge, and practical experiences during the process.

The final discussion deepens the understanding of the results by relating them to three distinctive parts of the knowledge creation process: from data to information, from information to knowledge, and from knowledge to use. Each section concludes with thoughts on practical implementation. Here, the importance of organizationally creating favorable conditions for maintaining work methods, reflection, and knowledge use are highlighted. Additionally, it is suggested that there needs to be flexibility in ISF work methods to adapt to changes in what the organization perceives as relevant to follow up, in order to promote new knowledge.
Reflections on the Use of Interactive Whiteboards in Instruction in International Context
Authors:   Palacký University in Olomouc, Dostál Jiří
Published: February 2025

The article discusses up-to-date problems entailed in the use of interactive whiteboards in instruction. The author reflects on their use in the international context and evaluates the results of previous research. Further, the methodological and technical aspects of the use of interactive whiteboards and specificity of creating interactive instructional presentations are dealt with.
The Mercator projection on the sphere: a deduction without mathematical gaps
Authors: Ramos Isaac , De Seixas Andrea , Jacks dos Anjos Garnés Silvio , Gonzales Lima Pereira Calado Lucas
Published: February 2025

Map projection is the mathematical process of converting the Earth's surface, considered as a sphere or an ellipsoid, into a map. This conversion is performed by projecting the Earth's points onto a surface, which can be a plane, a cone, or a cylinder. Its basic objective is to develop a mathematical basis for creating maps, essential in areas such as cartography, geodesy, and navigation. It would be ideal if all maps were isometric, but for large areas, the curvature of the Earth makes it impossible, causing distortions. For the reasons above, the mathematics behind map projection is complex, but it is important to understand it. Among the most varied types, the Mercator projection, created by Gerard Mercator in 1569, is a conformal cylindrical projection, widely used in navigation, as it represents the rhumb lines on the map as straight lines, but, despite preserving angles, it generates other distortions. The objective of this article is to present a mathematical derivation as complete as possible of the Mercator projection on the sphere, with the purpose of avoiding simplifications and omissions as much as possible, and, as an application, to use the deduced equations to implement in Python a visualization of the continents.
Dynamic Seating in Learners with Down's Syndrome in South Africa
Authors: Reyneke Lise Kathleen , Hoosain Munira
Published: February 2025

Introduction: The study aimed to investigate whether the classroom behaviour and task performance of learners with Down syndrome improved with the use of a stability ball as a classroom chair.Method: A single-subject withdrawal design was utilised. There were three participants, aged ten to twelve, with Down syndrome in a special education classroom. Five phases of three weeks each were implemented alternately. Two phases incorporated usual classroom chairs and the other three phases made use of stability balls as chairs. Momentary time sampling was used to record learners' classroom behaviours in relation to their in-seat and on-task performance.Results: A substantial positive change was found in the learners' on-task performance when seated on stability balls instead ofof chairs. Results differed across participants; with some demonstrating a definite difference in the usual daily average on-task performance, while others showed steadier patterns of on-task behaviour in comparison with their usual fluctuating levels of attention.Conclusion: Stability ball seating is a non-invasive intervention strategy that can be effectively utilised in classrooms and occupational therapy clinical settings, to improve on-task behaviour in learners with Down syndrome
Key words: Dynamic seating, Down syndrome, attention, in-seat behaviour, on-task behaviour
Filiczki János Konrad Rittershausen házasságára írt versének autográf hamburgi kézirata
Authors: Molnár Dávid
Published: February 2025

Filiczki János egy versének imeretlen, autográf verziója Hamburgból.
Heltai Gáspár Biblia-idézési módszere életművében
Authors: Kőrösi Ferenc
Published: February 2025

A tanulmány fő kérdése, hogy Heltai Gáspár milyen módszerrel idéz a Bibliából saját munkáiban. A kiindulópontot az a Pázmány Péter munkái kapcsán megfogalmazott nézőpont adja, miszerint Pázmány tudatos módszert alakított ki az idézéshez. Annak feltárásához, hogy Heltai alkalmazott-e valamilyen tudatos szerkesztési metódust e tekintetben, illetőleg, milyen elvek figyelhetőek meg, a vizsgálat középpontjában a Heltai művek elemzése állt. Kutatásaim során négy kérdés mentén vizsgáltam a Heltai szövegekben található bibliai idézeteket. Arra kerestem választ, hogy milyen kapcsolatban állnak a művekben található idézetek Heltai részleges Biblia-fordításaival. Emellett az is a vizsgálat tárgya volt, hogy egy idézet többszöri megjelenése esetében azonos, vagy eltérő formában került-e erre sor. Az összehasonlító és szövegelemző vizsgálatok arra mutattak rá, hogy éles határ húzható meg az idézés módszerében Heltai korai és késői munkásságában. Míg korai munkáiban Heltai többnyire szó szerint idézi a Biblia szövegét (főképp az Ószövetség könyveit), addig kései műveiben már elsősorban átdolgozásokkal, paratextusokkal találkozunk. Ennek két oka lehet. Az első, hogy míg korai munkái megjelenésekor már rendelkezésére állt Heltainak az Ószövetség fordításának nagy része, addig az Újszövetségé nem. A másik ok abban látható, hogy Heltai, munkásságának második felében, áttért a dogmatikai kiadványok megjelentetéséről az erkölcsi példákat nyújtó történetek közreadására. Míg előbbi esetében a tévtanok elkerülése megkövetelte a pontos idézést, addig az utóbbi nyomtatványok esetében fontosabb volt az idézetek beágyazása a szövegbe.
Esterházy Pál bécsi kiadványai
Authors: Viskolcz Noémi
Published: February 2025

Esterházy Pál herceg (1635-1713) és magyar nádor kora jól ismert mecénása volt, egyben alkotó ember, akinek irodalmi, művészi és zenei tehetsége is megmutatkozott. Fiai tanulmányai során került kapcsolatba bécsi nyomdászokkal, amikor tézislapjaikat és Szent László-napi beszédeiket kiadatta. Az 1690-es évtizedben a saját latin nyelvű kegyességi művei és családtörténete kinyomtatásával a nagy és patinás műhellyel rendelkező Leopold Voigtot bízta meg, összesen öt műve jelent meg a császárvárosban. A bécsi helyszínválasztás elsődleges mozgatórugója az volt, hogy az császárnak és a környezetének is megmutathassa különleges képességeit, nemcsak azt, hogy milyen nagylelkű mecénás, hanem azt is, hogy a teológiában jártas, a hitében elmélyült és a pietas austriacát értő író is. Ezt az elismerésre vágyó reprezentálás szándékát támasztja alá a fennmaradt jeles névsor, amely szerint a Via Lactea 1691 végén kinyomtatott 200 példányából majdnem harmincat a bécsi udvarban osztottak szét. Nem ismert, hogy a nádor a másik négy bécsi könyvét eljuttatta-e az előkelő bécsi köröknek, de tény, hogy hasonló cél vezette 1700-ban a családja múltját és előkelőségét összefoglaló Trophaeum megjelenésekor is. Esterházy Pál ambícióiról sokat elárul a Bécsben a jezsuita egyetemen létrehozott alapítványa, amelynek feladata volt a teológushallgatók Szeplőtelen Szűz Máriáról szóló beszédeinek kiadása, legalább 11 ilyen, ugyancsak Leopold Voigtnál évente megjelent kisnyomtatványról tudunk. Ezek ékessége a címlap elé helyezett Győzedelmes Mária-metszet, a 11 év alatt négy különböző megformálásban.
A szultáni szerájtól a párizsi Királyi Könyvtárig
Authors: Tóth Ferenc
Published: February 2025

A Bibliothèque nationale de France kéziratok osztálya az egyik legfontosabb központi francia gyűjtemény. Az ott őrzött, magyar jelentőségű kéziratok között megtalálható Ptolemaiosz Kozmográfiájának latin fordítása, amely korábban a Mátyás király Corvina könyvtárához tartozott. Ez az értékes kézirat valószínűleg a mohácsi csata (1526) után került Konstantinápolyba, és a 18. században a Bibliothèque du Roi (jelenlegi Bibliothèque nationale de France) gyűjteményébe került. E kézirat megszerzésének körülményei mindeddig homályban maradtak. Az új kutatás kimutatta, hogy egy magyar származású francia diplomata és katona fedezte fel a Szerailban az 1770-es években, és felajánlotta a külügyminiszternek, Vergennes grófjának. A levéltári források irodalmi forrásokkal való összehasonlításával a tanulmány rávilágít a francia diplomaták kulturális közvetítői szerepére az Ancien Régime végén.
A kora újkori magyarországi könyvtárak Széchényi Ferenc alapításáig – kutatástörténeti áttekintés
Authors: Zvara Edina
Published: February 2025

A könyvtártörténeti kutatások áttekintésekor az egyik legfontosabb és legnagyobb eredmény, hogy az 1979-ben Szegeden Keserű Bálint, majd Monok István vezetésével megkezdett, illetve szervezett munkálatok a közelmúltban tulajdonképpen lezártnak tekinthetőek. Az elmúlt negyvenöt év kutatásai azt mutatják, hogy számos forrás megőrződött, és ezek alapján nemcsak árnyalni lehet a korábbi szakirodalmakban megjelent megállapításokat, hanem esetenként át is lehet azokat értékelni, és emellett új eredmények is születnek. A hazai könyvtártörténeti alapkutatások eredményei több sorozatban jelentek meg, s ezek mindegyike elektronikusan is elérhető. A fehér foltok közé tartozik többek között a 18. század második felében keletkezett forrásoknak – különösen a szerzetesrendi könyvtárak jegyzékeinek – mind a kiadása, mind a feldolgozása. Több hazai közgyűjteménynek hiányzik még alapkatalógusa, legyen az ősnyomtatvány vagy régi könyvek 1850-ig katalógusa. A régi/új témák közé tartozhat az ismert könyvjegyzékek vagy könyvállományok több szempontból történő, áttekintő elemzése. Több művelődéstörténeti szempontból kiemelkedőn fontos személy könyveiről alig tudunk valamit, pedig életműve gazdag könyvtárat feltételez. Egykori gyűjteményük rekonstruálására kiváló eszköz (lehetne) az eruditio-adatbázis, amibe legalább már az ismert, elszórtan megjelent adatokat lehetne rögzíteni.
A 16–17. századi Kárpát-medence olvasmánytörténete
Authors: Oláh Róbert
Published: February 2025

A tanulmány a 16-17. századi Kárpát-medence olvasmánytörténeti kutatásait tekinti át. A magánkönyvtárak olvasóit ismerhetjük meg a nemességről, a katolikus főpapságról, az értelmiségről, a polgárságról és a nőkről szóló alfejezetekben. Az intézményi könyvtárakról felekezeti bontásban tájékozódhatunk. Végül az olvasmánytörténeti tendenciákat ismertetjük és felmutatunk néhány olyan területet a kutatásokban, amelyek nem kellőképpen feltártak.
Multilocus identification and pathogenetic characterization of Colletotrichum endophyte and pathogen species isolated from cocoa leaves and pods (Theobroma cacao) in Ecuador
Authors: Espinoza-Lozano Fernando , Villavicencio-Vasquez Mirian , Serrano Lizette , Sosa Daynet , Coronel-León Jonathan , Vera-Morales Marcos
Published: February 2025

Cacao cultivation is one of the main agricultural products of Ecuador, known internationally for its quality and aroma. However, it is affected by fungal diseases including Moniliophthora roreri, Moniliophthora perniciosa, Phytophthora spp., and Colletotrichum spp. The genus Colletotrichum spp. is known for its characteristics that complicate traditional taxonomic identification. In cacao cultivation, it is one of the most frequently found species as an endophyte of leaves and fruits, yet it is also reported to cause the disease known as anthracnose on leaves and fruits. The objective of this work was to identify at the species level 16 Colletotrichum isolates, 13 from healthy leaf endophytes and 3 from pods with symptoms, through multilocus analysis of the ITS1, 5.8S, and ITS2 region, and partial sequences of the TUB2 and GAPDH genes. Subsequently, their pathogenicity was evaluated by inoculating healthy cacao pods and measuring the damage caused. The 16 isolates were identified as follows: from the gloeosporioides complex, C. siamense 6, C. chrysophilum 6, C. theobromicola 2 and from the boninense complex, C. karstii 2. The most frequently found species were those that caused symptoms, especially C. siamense, to which the strains were isolated from symptomatic pods belonged. This work provides relevant and accurate information about the diversity of Colletotrichum species that colonize cocoa plantations and identifies which species might cause the disease known as anthracnose. Additionally, it allows for a more precise diagnosis and consequently better treatment.
Transport Properties of Niobium Doped Silver-Borate Glasses
Authors:   Associate Professor, Department of Physics, Govt. First Grade College, K.R. Puram, Bangalore, 560036, Karnataka, India, Sathish M , Nayaka Ravikumara , Dinesh C M , Mathad Gavisiddayya , Pathar Deepa , Shivaprakash Y
Published: February 2025

Objective: To create a broad composition range of Nb2O5 doped silver-borate glasses without adding any reducing chemical agents and to achieve ac-dc conduction mechanism. Methods: Borate glasses compositions, (1-x)Nb2O5- 65B2O-(35-x)Ag2O, (Where x=0.1 to 0.5 mol%) have been synthesized by conventional melt-quenching technique. Temperature dependent conductivity over a wide range of frequency (40-10MHz) has been performed. Findings: Only one semicircle is visible in the impedance plots, suggesting the existence of a single kind of conduction mechanism. Fitting the data to the Almond West type power law behavior, 𝜎(𝜔) = 𝜎0 + 𝐴𝜔𝑠 is used for the analysis of the ac conductivity. It is also discovered that the power law exponent ”s” rises as the temperature rises. Indicating the temperature dependence of the conductivity of the samples. Novelty: The preparation of niobium doped silver-borate glass samples is achieved without the reducing agents and established the wide range of conduction mechanism by both Nb+ and Ag+ ions for the first time.

Keywords: Glass; Transport Properties; AC-DC Conductivity; Ag-Ions; Almond-West Power Law
Manual Uterine Tissue Dissociation for Multiome Analysis v1
Authors: A Johnston Sarah , O'Neill Kate , Fisher Stephen , Kim Junhyong
Published: February 2025

This protocol was developed in accordance with the mission statement of the Human BioMolecular Atlas Program (HuBMAP) of the NIH, to create an open and global platform to map healthy cells in the human body. Protocols developed through HuBMAP can be used by researchers across the world to create Standard Operating Protocols (SOPs) for sample collection and processing. This protocol describes dissociation of snap-frozen uterine tissues in order to isolate nuclei that can be used for downstream molecular analysis. This protocol can also be used on cell suspensions made from fresh tissue; freezing tissues leads to a slight decrease in RNA quality after tissue thawing and dissociation. If using fresh tissue, we recommend optimizing the lysis time. We use this protocol to generate high quality 10X Multiome libraries from snap-frozen uterine and cervix tissue biopsies.
Optogenetic Silencing of Projection Terminals v1
Authors: H. Roth Richard , B. Ding Jun
Published: February 2025

This protocol describes the combination of protocols and techniques that are employed to optogenetically silence projections from various areas in the brain.
Нация и молодежь (диалог со Скептиком в форме самоинтервью)
Authors: Ильинский Игорь Михайлович
Published: February 2025

Статья известного социального философа, президента Московского гуманитарного университета И. М. Ильинского посвящена проблеме формирования российской нации в новых социально-экономических, политических и геополитических условиях. Основной тезис статьи: политика нациестроительства в России должна опираться на традиционные российские ценности (прежде всего приоритет духовного над материальным) и одновременно быть направлена на воспитание новых поколений (молодежи). Именно целенаправленная воспитательная политика государства, по мнению автора, может стать основным противоядием против насаждавшихся в России долгое время (с начала 1990-х гг.) чуждых ей ценностей и основой формирования подлинной гражданской нации.

Текст написан в 2009 г., но републикуется сегодня в связи с большой актуальностью высказанных в нем идей.
Трансформация военных конфликтов современности и появление новых понятий в политическом и военном тезаурусе
Authors: Бартош Александр Александрович
Published: February 2025

Актуальность статьи обусловлена изменением стратегий военных конфликтов ХХI в., появлением гибридной войны как нового вида межгосударственного противоборства и настоятельной необходимостью сформулировать важные, системообразующие определения понятийного аппарата теории гибридной войны как части политического и военного тезауруса.

Трансформации стратегических взглядов на войну привели к изменению политического, дипломатического и военного лексикона и к появлению не существовавших ранее социально-политических понятий, требующих осмысления в философских и военно-политических категориях, отражения их в соответствующих разделах тезауруса.

Новизна предпринятой автором попытки теоретического рассмотрения влияния феномена гибридной войны на понятийный аппарат военных конфликтов современности связана с отражением используемых в политике, дипломатии и военном деле новых ключевых терминов (понятий), описывающих феномен гибридной войны как новую предметную область, с указанием семантических отношений (связей) между терминами (понятиями).
Цифровая трансформация кадровой политики образовательных организаций высшего образования в России
Authors: Гурина Елена Алексеевна , Курбатова Мария Романовна
Published: February 2025

В статье представлен анализ актуальных проблем управления человеческими ресурсами в образовательных организациях высшего образования в современной цифровой экономике, основанный на положении о том, что кадровая политика сегодня определяет основные направления деятельности для обеспечения успешного функционирования учебного заведения. Авторами обозначены ключевые моменты работы HR-специалистов образовательных организаций, способствующие повышению их эффективности, а также рассмотрен процесс внедрения и особенности использования цифровых технологий, позволяющих автоматизировать рутинные операции и повысить результативность взаимодействия между сотрудниками.