bluuebunny/crossref_metadata_2025 huggingface dataset:
ASSOCIATION OF MATERNAL SERUM TOTAL PROTEIN AND ALBUMIN LEVEL WITH BIRTH WEIGHT OF NEWBORN
Authors: S Panwar Bhuvanesh
Published: June 2023

Background: Low birth weight is a leading cause of Neonatal Mortality. Lack of Nutrients and less intake of Nutrients and minerals during pregnancy is associated with Low birth weight of newborn. To Evaluate the Ass Objective: ociation of Maternal serum Total protein and Albumin levels with birth weight of newborn. A Total of 75 Healthy Mothers of Newborns wi Methods: th Low Birth weight (Birth weight <2.5 Kgs.) were selected as cases and 75 Healthy Mothers of Newborns with Normal Birth weight (Birth weight>2.5 Kgs.) were selected as controls. Serum Total proteins and Serum Albumins were measured in all study subjects. Serum Total proteins were done by Biuret Method and Albumins by BCG Dye Method. Birth weight of Newborns were taken by Beam Balance Scale method at the time of Birth. The study found that the mean levels of Results: Serum Total protein and Serum Albumin in cases (Mothers having LBW newborns) were signicantly lower than the Controls (Mothers having NBW newborns). Mean Serum Total protein and Serum Albumin in cases were 4.98±0.57 gm/dL and 2.65±0.29 gm/dL respectively, while in controls 6.90±0.61gm/dL and 4.06±0.63 gm/dL respectively. Birth weight of newborns showed a posit Conclusion: ive, Signicant and strong Correlation with Maternal Serum Total Protein ('r' = 0.985, p<0.0001) and Maternal Serum Albumin ('r' = 0.961, p<0.0001)
BELL'S PALSY IN PREGNANCY AND PUERPERIUM: A CASE REPORT
Authors: Vaidya Maithily , Bambare Rohini , Rokade Jyoti
Published: June 2023

Bell's Palsy is an idiopathic facial nerve palsy and also the most common cause of facial nerve palsy. It's incidence is 17/100,000 population per year in women of child bearing age group(WCBA). We, hereby present a case of 26 year old gravida 2, para 1, living 1 with 35 weeks of gestation who presented with gradual onset of facial weakness and few other complaints which after thorough examination were suggestive of Bell's palsy in a case of pre eclampsia. Patient was later posted for C-section at 36 weeks for scar tenderness. In the post operative period patient was on steroids for persistent facial nerve palsy but the patient landed in an unusual complication due to on going steroids as she had failed to follow up. Patient was taken up for exploratory laparotomy, patient tolerated the procedure well and went home on POD-42. Amongst the medications used in this patient for Bell's palsy, we saw that steroids could thus act as a double edged sword and thus close monitoring, follow up and patient compliance is equally important
VERY RARE COMBINATION OF PATENT VITELLOINTESTINAL DUCT WITH PATENT URACHUS
Authors: R. Chaudhari Archana , R. Harbade Suresh , S. Vairagad Pankaj , P. Jadhav Sarojini
Published: June 2023

Introduction - The vitelline duct is the embryological narrow channel connecting the yolk sac with the intestine. During the foetal life, vitelline duct tends to obliterates itself till to disappear. The partial failure of this obliteration can lead to the development of a duct, a ligament, or a diverticulum known as a Meckel's diverticulum. A Patent omphalomesenteric duct occurs because of the complete lack of vitelline duct.[3] The urachus is an embryological remnant of the allantois. Between the fourth and fth month of gestation, the foetal bladder tends to descend gradually and its apical portion creates the urachus. The urachus obliterates itself, becoming the median umbilical ligament. Its persistence after intrauterine life can manifest as urachal remnants. A patent urachus is because of complete lack of obliteration of urachus [1,3]. The incidence of these anomalies PU was 1-2 per 10000 while PVD is 1 in 5000 to 8000 deliveries [1,3,5]. The association of both anomalies is very rare [7]. Case discussion- A 12-years-old male presented with complaints of pain in abdomen, multiple episodes of vomiting. Patient was tachycardiac with tenderness in right iliac fossa with palpable lump with ultrasonography suggestive of perforated appendix with lump formation and was managed conservatively and asked for interval appendicectomy with CECT abdomen. CECT was suggestive of normal and compressible appendix with infected urachal cyst. But after 4weeks patient had similar complaints hence posted for emergency operation with McBurney's incision not by midline incision to avoid injury to urachal cyst. Intra operative ndings-1) patent Vitello intestinal duct 2) patent urachus 3)15cc pus discharge near umbilical end of urachus 4) normal appendix and small bowel. Resection of Vitello intestinal duct and urachus with ileoileal anastomosis done and specimen sent for histopathology which was suggestive of patent vitello intestinal duct with changes of gangrene. The Patent Vitello Conclusionintestinal duct with patent urachus is very rarely seen in combination and its diagnosis may be missed preoperatively and should be kept as a possibility in patients with patent urachus with or without infection
THE EFFECTS OF NUTRITION ON THE COGNITIVE DEVELOPMENT OF CHILDREN WITH LEARNING DISABILITIES
Authors: D Nambisan Divya , Harish Rasitha
Published: June 2023

A cognitive dysfunction is not a question of skill or creativity. Many aspects, including spoken or nonverbal therapy, organization, acquisition, or knowledge application, are associated with learning difculties. Children with autism are not dumb or lethargic. They are all just as clever as anybody else. Their brains were just structured differently. The status of micronutrients may impact cognitive performance at any age. Insufcient nutrients and trace elements may affect memory, resulting in learning impairment. Food is a changeable lifestyle factor that may signicantly affect learning impairment pathophysiology. This study investigated the inuence of micronutrients on the cognitive functioning of children with intellectual challenges. This study attempted to evaluate the function of nutrients in monitoring the progress of children with impairments and their prognosis and treatment. Our study reveals unequivocally that micronutrient status is strongly connected with intellectual disability and that correcting dietary decits following language treatment dramatically improves the learning capacity of children with learning disabilities (LD). Although micronutrient deciencies typically co-occur in the context of deprivation, little is known about the impact of several micronutrient deciencies on cognitive development. This research examines the relationship between four micronutrient deciencies and children's cognitive performance.
THE PROSPECTIVE STUDY OF COAGULATION PROFILE IN CHRONIC LIVER DISEASES AT TERTIARY CARE CENTRE.
Authors: V. Agrawal Kashmira , S. Dhawle Manjusha , R. Joshi Anil
Published: June 2023

Background:- The liver is the body's largest and a vital organ and plays a major role in haemostasis, as most of the coagulation factors,
anticoagulant proteins and components of the brinolysis system are synthesized here. Balance between these procoagulant and anticoagulant
processes is essential to prevent unwanted thrombin generation under normal physiological conditions. Objectives:-To study coagulation defects
in patients of chronic liver diseases and to assess the effect of chronic liver diseases on intrinsic and extrinsic pathway through various coagulation
tests and its correlation with platelet count. Materials and Methods :- Total 100 cases suffering from liver cirrhosis, chronic hepatitis and
hepatocellular carcinoma admitted in medical and surgical wards were studied. Venous blood was collected and coagulation tests like BT, PT,
APTT, D-dimer were done. Result :- Out of 100 cases of chronic liver diseases, 58% were diagnosed as liver cirrhosis, 37% were chronic hepatitis
and 4% were hepatocellular carcinoma. The commonest coagulation defect in chronic liver diseases was prolonged PT. BT,PT,APTT, D-dimer
was signicantly increased and platelet count decreased in hepatocellular carcinoma and liver cirrhosis but within normal range in chronic
hepatitis. Conclusion:- Laboratory tests suggest the abnormality in coagulation system which if done routinely can be helpful in better
management of patients with liver diseases.
SYNCHRONOUS MALIGNANCY OF PAPILLARY THYROID CARCINOMA AND HODGKINS LYMPHOMA IN A YOUNG PATIENT
Authors: Sharma Vishnu , Bagrodia Vansh
Published: June 2023

Here, we report the case of a 35-year-old man who presented with fever and swelling on right side of neck. Radiological examination pointed towards a diagnosis of cancer for which total thyroidectomy along with neck dissection was done. Histopathology ndings conrmed papillary thyroid carcinoma and incidental nding of Hodgkin's lymphoma in lymph nodes. The patient was started on chemotherapy (ABVD) and his symptoms started to improve. The second primary malignancy is a second malignant neoplasm occurring in a patient with known cancer. This case highlights the uncommon phenomenon of the double primary malignancy of PTC and HL and the medical challenges involved in management of such cases
DESCRIPTIVE STUDY OF SENTINEL LYMPH NODES /AXILLARY SAMPLING ON FROZEN SECTION IN CASES OF CARCINOMA OF BREAST
Authors: Karande Dipmala , Ajmera . Rakeshkumar , Konkandakar Hemant , Nilkanth Somesh , Joshi Anil
Published: June 2023

Background: The frozen section provides rapid diagnosis to guide intra or perioperative patient management. Intraoperative frozen sections of
sentinel lymph nodes can be used to identify metastatic disease, allowing immediate axillary lymph node dissection. To Study Sentinel Aims:
Lymph node /Axillary Sampling on Frozen Section in Cases of Carcinoma of the Breast and to assess the accuracy of frozen section diagnosis.
Materials and Methods: - An observational descriptive study was carried out in the department of pathology. A total of 33 patients were evaluated
during January 2021 to July 2022. SLNs were examined using standard frozen section procedure and sections were stained with rapid H &E.
Patients with positive SLN on FS underwent ALND. The remaining frozen tissue was processed for routine histopathology processing. Results: -
Out of 33 cases, 9 (27.27%) cases are positive on the frozen section and 24 (72.72 %) cases are negative on the frozen section. However, on the
parafn section, 14 (42.42%) cases are positive and 19 (57.57 %) are negative. There was no false positive case (specicity-100%). 14 cases show
tumour deposit in sentinel lymph node. 13 cases had macro-metastatic tumour deposit and 01 case shows micro-metastatic tumour deposit. The
diagnostic accuracy is 84.84% and sensitivity 64.28%. Intraoperative frozen section diagnosi Conclusions: - s of sentinel lymph nodes in cases of
carcinoma of breast can identify metastatic disease, allowing immediate axillary dissection, if necessary, thus avoiding the need for reoperation.
Arm and shoulder morbidity caused by axillary lymph node dissection (ALND) can be avoided in cases where it was not indicated on frozen
section.
A CROSS-SECTIONAL STUDY OF RECOVERY PATTERN IN WATERSHED INFARCTS IN A TERTIARY CARE CENTRE.
Authors: N Anand , S Saravanan , S Ravi
Published: June 2023

Background: Acute ischaemic stroke is one of the leading causes of morbidity along with cancers and cardiovascular diseases. Millions suffer from acute ischaemic stroke every year worldwide of which 5% suffer from watershed infarcts(1). The aetiopathogenesis and recovery from decits in watershed infarcts are different from territorial infarcts. The identication of specic features of recovery pattern and pathogenesis of infarcts may throw more light on these diseases as modern-day treatment of stroke is mainly concentrated on the treatment of territorial infarcts like endovascular procedures. This study may help to ll that gap. Aim: To study the recovery pattern in acute watershed infarcts. Methodology: 153 patients with acute watershed infarcts were studied. Detailed examination, NIHSS Score, mRS scale and Barthel index were assessed at the presentation and after 90 days of follow-up. Patients with Cognitive impairments were assessed and followed up after 90 days. Statistical analyses were done using SPSS 25.0 software for Windows. Chi-square and independent t-tests were applied to analyze categorical and numerical data, respectively. Results: A total of 153 patients out of the 2233 acute strokes were studied. The mean NIHSS score, mRS scale, and Barthel Index in patients of watershed infarcts are 10.9,3.1,62.9, and after 90 days are 7.9,2.3, and 74.5 respectively. The comparison was statistically signicant. Most patients had signicant motor improvement and cognitive improvement. The most common etiology was Internal Carotid artery thrombosis which also had the best prognosis. Conclusion: The pathogenesis and recovery in Watershed Infarcts are different from that of territorial infarcts. Prognosis and Recovery depend upon the etiology. Both Motor and Cognition recovery in watershed infarcts is signicantly higher
PITUITARY ABSCESS – A RARE CASE REPORT
Authors: Bhuyan Mrinal , Pratim Boruah Manash
Published: June 2023

Study Design: Case Report To report a rare case of Pituitary Abscess, its management and Objective: outcome. A 15-year-old boy Background:
presented with history of headache on and off for the past 9 months. MRI revealed a peripheral rim enhancing lesion in the sellar region. Patient
underwent Right Frontal Craniotomy, Subfrontal Approach wherein there was pus in the sellar region which was aspirated. Patient was started on
antibiotic therapy and on follow up patient got relieved of his symptoms. Pituita Conclusion: ry Abscess is a very rare disease of the sellar region
that is difcult to correctly diagnose on the basis of clinical manifestations and MRI. Despite its rareness, a Pituitary Abscess must be considered in
the case of a pituitary mass associated with signs of raised Intracranial Pressure with/without pituitary hormone dysregulation and signs of
infection. The treatment is a combination of surgery, antibiotics, and hormone substitution whenever needed
A STUDY OF LENGTH OF HOSPITAL STAY OF COVID-19 PATIENTS ADMITTED IN A DEDICARED COVID-19 HOSPITAL IN UDAIPUR
Authors: Keerti Keerti , Pratap Singh Jadon Hitesh , Meena Anuradha , Kumar Parmar Lokesh , Kumar Parasar Satyendra
Published: June 2023

Background :- The ongoing coronavirus disease 2019 ( covid-19 ) pandemic has placed an unprecedented strain on indian healthcare systems, with rapidly increasing demand for life-saving equipment and intensive care unit beds. The present study presents an analysis of average length of stay as per different demographic and clinical factors in a dedicated covid hospital. Objectives: 1) To study the clinical and epidemiological prole of Covid 19 patient. 2) To study about relation between patient's length of stay with their clinical characteristics Method: A hospital based Retrospective crosssectional study in which All RTPCR conrmed Cases who got hospitalization and got treated during 19 months(from March 2020 till September 2021)of the rst RTPCR conrmed case in study area. Result: This study reported that out of the total 8027 study population higher proportion of Males that is 5229 (65.14%) were affected as compare to females 2798(34.86%). Mean age of this study population was 53.13 ± 20.13 year, and median age was 39 years. In our study we found that out of total 16.05% severely ill , mild 39.85% and moderate 44.10%. Duration of stay of symptomatic patients was higher 16.14 ± 4.41 days as compare to asymptomatic patients 11.11 ± 3.95 days. Association between duration of stay with symptoms was statistically signicant (p=<0.001). In our study average length of stay for male patients were 15.49±4.32 days and female was 16.08±4.54 days and average length of stay of patients with comorbidity were 17.23±4.57 days and without comorbidity were 13.57±4.08 days. Conclusion: average length of stay was higher in patients with comorbidity and patients who were symptomatic.
ASSESSMENT OF NUTRITIONAL STATUS IN CHRONIC OBSTRUCTIVE AIRWAY DISEASE PATIENTS WITH RESPECT TO SEVERITY
Authors: Lokesh Lokesh , V. N Prashanth , M Ramesh
Published: June 2023

Introduction: Chronic obstructive pulmonary disease (COPD), the fourth leading cause of death in the world, represents an important public health challenge that is both preventable and treatable. Weight loss, muscle mass and fat mass depletion are common nutritional problems in COPD patients. To investigate the nutritional status of COPD patients with Objective: anthropometric parameters such as Body Mass Index (BMI), muscle mass, skin fold thickness, percentage of fat and Mini Nutritional Assessment (MNA), and biochemical parameters such as total protein and serum albumin. All the above parameters were then correlated with the severity of pulmonary dysfunction using a Pulmonary Function Test (PFT). Methodology: The present cross sectional study was conducted on 65 patients with stable COPD status, satisfying inclusion and exclusion criteria and admitted in hospitals attached to Bangalore Medical College & Research Institute. Wit Result: h increasing severity of COPD a signicant decrease in BMI, skin fold thickness, muscle mass, percentage of fat, mean MNA score, hemoglobin, total protein, albumin and lipid were noted. Conclusion: Malnutrition worsens the severity of airway obstruction in COPD patients. Therefore, nutritional status should be evaluated and nutritional intake should be tailored individually for every COPD patient
STRESS, ANXIETY, WORK-RELATED BURNOUT AMONG PRIMARY HEALTH CARE WORKER: A COMMUNITY-BASED CROSS-SECTIONAL STUDY.
Authors: Parmar Alpesh , Gohil Khushbu , Abhilasha Murmu Anupama , Bharatbhai Gandhi Rohankumar , Patel Bela , Shubham Shaileshbhai Patel
Published: June 2023

The majority of national policies are successfully implemented at the local level because of primary health care providers. Workplace stress is a change in one's emotional or physical status as a result of their job. They are more likely to experience work-related anxiety and burnout. The present study was undertaken to assess the occurrence of psychological distress, anxiety, and burnout among primary Healthcare workers. Methodology- It is a community-based cross-sectional study that was conducted over the period of 6 months from September 2022 to February 2023 at various Primary Health centres of Mundra taluka, Gujarat. Results- 154 participants were recruited. Out of 154 study participants, 55.84% had mild anxiety, 37.01% had moderate, and 7.15% had severe anxiety levels. Among the same participants, 56.49% had mild stress, 31.17% had moderate stress and 12.34% had severe stress. With respect to burnout, 3.90% had no personal burnout, 22.08% had moderate burnout and 74.02% had high burnout. Conclusion- According to the current study, primary healthcare workers frequently experience stress, worry, and burnout connected to their jobs. Screening regularly for stress, anxiety, and work-related burnout at the workplace is the need of the hour.
ASSESSMENT OF REFERRING CLINICIAN'S ADHERENCE TO ROYAL COLLEGE OF RADIOLOGISTS GUIDELINES FOR ABDOMINAL RADIOGRAPHY
Authors: Nikhil Maruti Jadhav , Khushboo Prakash Votavat
Published: June 2023

Introduction: One of the commonest complaints encountered in the emergency department is acute abdominal pain and the most common investigation ordered to evaluate it is an abdominal X-ray (AXR). However many studies have shown that AXR has a low diagnostic yield and this investigation may be overused. So in order to optimize the sensitivity of AXR, the Royal College of Radiologists (RCR) introduced the iRefer guidelines. Aims: This study aims to assess referring clinicians' adherence to iRefer guidelines for abdominal radiography. And to determine whether the professional status of the referring clinician inuences their adherence to the guideline. Methodology: This is a retrospective study of consecutive adult patients, who presented to a rural tertiary care center between October 2020 and March 2021. Indications for AXR and clinician seniority were determined from the radiology request slips. The appropriateness of imaging was determined by comparing the indication for abdominal radiographs to iRefer guidelines by the Royal College of Radiology. Data was then analyzed accordingly. Results: Our study included 100 patients. 22% of abdominal radiographs were requested according to the iRefer guidelines while 78% were against the guidelines (p-Value = 0.0001). Out of 22 radiographs adhering to iRefer Guidelines, 7 radiographs were normal and 15 were abnormal (14 correct and 1 incorrect in comparison to gold standard). Also, out of 78 radiographs not adhering to the guidelines, 59 radiographs were normal and 19 were abnormal (5 correct and 14 incorrect). Conclusion: The accuracy of detected abnormalities, if we adhere to iRefer guidelines, is 93%. Therefore, we need to follow the iRefer guidelines for every abdominal X-ray. Non-adherence to iRefer guidelines leads to unnecessary exposure of a patient to radiation and increased cost of treatment. To improve the patient's management we need to educate and inform the doctors of different levels about the guidelines.
TO ASSESS SUBCLINICAL UREMIC ENCEPHALOPATHY IN NEWLY DIAGNOSED CHRONIC KIDNEY DISEASE PATIENTS BY USING COGNITIVE PARAMETERS IN TERTIARY CARE CENTRE
Authors: Garg Shubham , Abdullah Sabiya , Mohod Varun , Kumar Sumeet
Published: June 2023

Background: Chronic kidney disease(CKD) is one of the leading cause of death in the world because of its late or end stage presentation. In our study we assessed patients of CKD for cognitive dysfunction with Addenbrooke scale and other biochemical parameters. Methods: This crosssectional study was conducted on 60 newly diagnosed CKD patients at MGM Medical College and MY Hospital Indore, MP, India, from 2019 to 2021. Baseline parameters like serum urea, creatinine, bilirubin and sodium were done and patients were subjected to Addenbrooke scale to assess subclinical uremic encephalopathy and data were analysed using SPSS statistics version 22.0 and p value <0.05 and condence interval more than 95% were considered signicant. Results: In my study of 60 patients, we have different mean of Addenbrooke scale according to stages. In stage 1 of CKD the mean value of scale is 94.33%. In CKD stage 2 the mean scale is 96.833% . In stage 3 CKD mean value is 94.5%. In CKD stage 4 the mean value is 91.2%. In CKD stage 5 the mean value is 86.88%. Conclusions: This study supports the fact that as CKD stages progresses, there is propensity of Addenbrooke score to decrease which helps in early detection of subclinical uremic encephalopathy and therefore the risk of uremic seizures
Оценка йогуртного продукта выработанного с применением вторичного молочного сырья - пахты
Authors: Канина Ксения Александровна , Красуля Ольга Николаевна , Жижин Николай Анатольевич
Published: June 2023

Введение. Физиологические нормы питания и поступление пищи обогащенными разными эссенциальными веществами является предметом изучения многих специалистов, в том числе и технологов. Поэтому важное значение имеет изучение свойств продуктов с применением функциональных групп веществ. Вторичное сырье является источником биологически и физиологически важных веществ, которое может применяться в обогащение продуктов питания, в том числе йогуртных продуктов, с целью уменьшения дефицита эссенциальных веществ, которые могут приводит к нарушению пищевого статуса, а также нести положительный экономический эффект  с точки зрения ресурсосберегающей технологии производства. Цель. Изучение технологии производства продукта на основе вторичного молочного сырья - пахты и определение его качественных показателей.Материалы и методы. Исследования проведены на кафедре технологии хранения и переработки продуктов животноводства РГАУ-МСХА им. К.А. Тимирязева совместно с Всероссийским научно-исследовательским институтом молочной промышленности. Сырье для производства йогурта и йогуртного продукта поставлялось из зоостанции  РГАУ – МСХА имени К.А. Тимирязева. Исследования сырья и молочных продуктов проводились по общепринятым методам. Результаты. В выработанных продуктах были изучены физико-химические и реологические показатели. На основе полученных данных установлено, что йогурный продукт, с применением вторичного сырья пахты обладает более низкой калорийностью по сравнению с классическим йогуртом из молока. Так же высокое содержание витаминов группы В в пахте, позволяет получать продукт с выраженными биологически активными свойствами.  Установлено, что в исследуемых образцах йогуртного продукта присутствовала микрофлора, характерная для традиционного йогурта, это - Str.thermophillus и Lbm.bulgaricus. Жизнеспособность клеток высокая, на конец срока хранения и она составила в среднем 5,04 *107 КОЕ/см3, что подтверждается показателем кислотообразования в продуктах - более 100 °Т Выводы. Разработанная технология производства йогуртного продукта является не только ресурсосберегающей, но и относится к сфере бережного производства. Полученный продукт так же можно рекомендовать в качестве диетического питания, как источник биологически активных веществ.
Дизайн эмпирического исследования: функциональное содержание и информативность
Authors: Тихонова Елена Викторовна , Косычева Марина Александровна
Published: June 2023

Введение. Корректно подобранный и описанный дизайн исследования определяет достоверность и надежность полученных в ходе оригинального эмпирического исследования результатов, поэтому исследователю важно не только понимать его архитектуру, но и выстраивать ее оптимальную итерацию.

Цель данной редакторской статьи - описать логику построения, функциональное содержание и оптимальный объем дизайна эмпирического исследования.

Архитектура дизайна исследования. Описаны этапы планирования исследования на основе “луковой модели” (философия исследования, подход к исследованию, выбор методологии, исследовательская стратегия, временной интервал, сбор данных и анализ),  которая позволяет читателю понять не только внешнюю, но и внутреннюю логику исследования.

Выводы. Материалы данной редакторской статьи призваны помочь авторам эффективно планировать эмпирическое исследование, осознавая не только его процессуальные аспекты, но и его философию,. Подобный подход повысит индекс читабельности статьи и привлечет к исследованию внимание читательской аудитории.
Triple-Tail Common-Mode Insensitive High-Speed Dynamic Comparator for Analog In-Memory Computing Architectures
Authors: krishna kummarapalli , rashid ria , nambath nandakumar
Published: June 2023

This paper presents a novel cascode cross coupled dynamic comparator that has good coomon-mode behaviour. Performance metrics such as delay, offset, rms noise, energy consumed per bit conversion are calculated andcompared with state of the art work.
PanVA: Pangenomic Variant Analysis
Authors: van den Brandt Astrid , Jonkheer Eef , van Workum Dirk-Jan , van de Wetering Huub , Smit Sandra , Vilanova Anna
Published: June 2023

Genomics researchers increasingly use multiple reference genomes to comprehensively explore genetic variants underlying differences in detectable characteristics between organisms. Pangenomes allow for an efficient data representation of multiple related genomes and their associated metadata. However, current visual analysis approaches for exploring these complex genotype-phenotype relationships are often based on single reference approaches or lack adequate support for interpreting the variants in the genomic context with heterogeneous (meta)data. This design study introduces PanVA, a visual analytics design for pangenomic variant analysis developed with the active participation of genomics researchers. The design uniquely combines tailored visual representations with interactions such as sorting, grouping, and aggregation, allowing users to navigate and explore different perspectives on complex genotype-phenotype relations. Through evaluation in the context of plants and pathogen research, we show that PanVA helps researchers explore variants in genes and generate hypotheses about their role in phenotypic variation.

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Citation information: A. van den Brandt, E. M. Jonkheer, D. J. M. van Workum, H. van de Wetering, S. Smit and A. Vilanova, "PanVA: Pangenomic Variant Analysis," in IEEE Transactions on Visualization and Computer Graphics, doi: 10.1109/TVCG.2023.3282364.
Problematika Pembelajaran Matematika Kelas VIII ditinjau dari Minat Belajar Siswa
Authors: Sumadi Suhartini
Published: June 2023

tujuan dalam penelitian ini adalah untuk menganalisis problematika matematika siswa kelas VIII berdasarkan minat belajar. Penelitian ini adalah penelitian kualitatif, yaitu penelitian yang data datanya adalah berupa kata kata, gambar gambar dan bukan angka angka, jenis penelitian ini adalah kualitatif deskriptif. Subjek dari penelitian ini adalah siswa dan guru mata pelajaran matematika kelas VIII Mts Terpadu Ar Roihan Lawang.Instrumen yang dipakai dalam penelitian ini adalah observasi, angket dan wawancara. Teknik pengumpulan data perlu dilakukan dengan tujuan agar mendapatkan data data yang valid dalam penelitian. Teknik pengumpulan data dalam penelitian ini adalah dengan  peneliti langsung terjun ke lapangan.Langkah-langkah yang dilakukan untuk menganalisis data yaitu menyusun data secara sistematis dan menjabarkannya, memilih dan memilah data yang penting, serta membuat kesimpulan. Simpulan dari penelitian ini adalah terdapat beberapa faktor yang menyebabkan kurangnya minat belajar siswa terhadap pembelajaran matematika, yaitu kesulitan belajar oleh siswa sehingga mengakibatkan kurangnya minat siswa dalam menjawab soal-soal yang diberikan guru; serta metode yang digunakan dalam pembelajaran sebagai penunjang proses belajar siswa.
ANALISIS KECEMASAN SISWA DALAM PROSES PEMBELAJARAN TERHADAP HASIL BELAJAR MATEMATIKA DI KELAS X MA MUHAMMADIYAH AIMAS
Authors: SAFITRI YUNI , Sumadi Suhartini , Sahidi Sahidi
Published: June 2023

tujuan dari penelitian ini adalah untuk Mendeskripsikan kecemasan siswa dalam proses pembelajaran terhadap hasil belajar peserta didik di kelas X MA Muhammadiyah Aimas. Jenis penelitian yang digunakan adalah penelitian kualitatif deskriptif., digunakan untuk meneliti pada kondisi objek yang alamiah, dimana peneliti adalah instrument kunci. Cara pengambilan subjek penelitian ini adalah dengan menggunakan tehnik purposive sampling, dimana dalam tekhnik ini menggunakan satu kelas di awal setelah itu dipilih 2 peserta didik untuk mewakili masing-masing kategori. Instrumen yang digunakan dalam penelitian ini adalah angket kecemasan, tes hasil belajar dan wawancara. Berdasarkan hasil penelitian dan pembahasan, maka dapat diambil kesimpulan bahwa, responden dengan skor angket kecemasan rendah, yaitu hasil belajar yang diperoleh siswa dapat memenuhi KKM karena persepsi individu menjadi turun, hanya memikirkan hal yang kecil saja dan mengabaikan yang lainnya, namun individu berusaha untuk dapat berpikir dengan tenang. Responden dengan kecemasan sedang, Kesimpulan dari tingkat kecemasan sedang hasil belajar yang diperoleh siswa tidak dapat memenuhi KKM dari sekolah karena Persepsi individu lebih memfokuskan hal yang penting saat itu saja dan mengesampingkan hal yang lainnya. Responden dengan kecemasan tinggi, Kesimpulan dari tingkat kecemasan tinggi skor hasil belajar yang didapat siswa tidak dapat memenuhi KKm karena, Persepsi individu menjadi turun, hanya memikirkan hal yang kecil saja dan mengabaikan yang lainnya, sehingga individu tidak dapat berpikir dengan tenang.
ANALISIS VISUALISASI TEORI VAN HIELE DALAM PEMECAHAN MASALAH MATEMATIKA PADA MATERI SEGITIGA KELAS VII SMP IT AL-GHUROBA
Authors: Lemau Kanisius Dore
Published: June 2023

Penelitian ini bertujuan untuk mengetahui kemampuan siswa dalam Pemecahan Masalah Geometri peserta didik pada level visualisasi berdasarkan Teori Van Hiele pada materi segitiga kelas VII SMP IT Al-ghuroba. Penelitian ini merupakan penelitian kualitatif dengan pendekatan studi kasus. Subjek penelitian adalah peserta didik kelas VII SMP IT Al-ghuroba sebanyak 3 orang dengan kemampuan matematika tinggi, sedang, dan rendah. Pengumpulan data menggunakan posttest berbentuk soal uraian sebanyak 3 nomor dan wawancara. Semua data yang dikumpulkan dianalisis secara deskriptif kualitatif. Hasil analisis data yang diperoleh bahwa pemahaman pemecahan masalah pada subjek level visualisasi siswa dengan kemampuan tinggi yaitu siswa mampu menggambarkan bentuk bangun secara benar dengan sisi tegak dan bentuk garis sesuai penampakannya, siswa mampu membedakan antara dua bentuk bangun segitiga yang berbeda dengan memberikan nama bangun segitiga, siswa mampu menghitung jumlah bangun ≥ 7 dan mampu memberi nama dari bentuk bangun.

Pemahaman pemecahan masalah pada subjek level visualisasi kemampuan sedang yaitu siswa mampu menggambarkan bentuk bangun secara benar dengan sisi tegak dan bentuk garis sesuai penampakannya, siswa mampu membedakan antara dua bentuk bangun segitiga yang berbeda dengan memberikan nama bangun segitiga, siswa mampu menghitung ˂ 7 atau hanya mampu memberi nama dari bentuk bangun bangun.

Pemahaman pemecahan masalah pada subjek level visualisasi dengan kemampuan rendah yaitu siswa mampu menggambarkan bangun dengan kemiripan pola yang sama namun dengan sisi yang kurang tegak, siswa mampu membedakan antara dua bentuk bangun segitiga yang berbeda dengan memberikan nama bangun segitiga, siswa mampu menghitung ˂ 7 atau hanya mampu memberi nama dari bentuk bangun.
KEMAMPUAN MENYELESAIKAN SOAL CERITA SISTEM PERSAMAAN LINEAR DUA VARIABEL (SPLDV) DENGAN METODE ELIMINASI DI KELAS VIII SMP NEGERI 15 KABUPATEN SORONG
Authors: Dogoni Theresia , Sahidi Sahidi , Astutik Heny Sri
Published: June 2023

Penelitian ini bertujuan untuk mengetahui kemampuan meyelesaikan soal cerita SPLDV denganmetode eliminasi. Penelitian ini merupakan penelitian kualitatif. Subjek penelitian ini adalahsiswa kelas VIII SMP Negeri 15 Kabupaten Sorong yang terdiri dari 6 orang pengupulan datamengunakan tes dan wawancara. Data dan analisis mengunakan pengupulan data, reduksi data,penyajian data dan penarikan kesimpulan hasil penelitian menujukan bahwa subjek dengankemampuan tinggi dalam menyelesaikan soal cerita dengan metode eliminasi sudah mampudalam memahami soal, membuat model matematika, menyelesaikan dan menarik kesimpulan,sedangkan subjek dengan kemampuan sedang hanya mampu memodelkan matematika dansubjek kemapuan rendah sudah paham dalam tahap penyelesaian tetapi kurang teliti dalam tahappengerjaan sehingga tidak mendapatkan hasil yang benar.
KEMAMPUAN BERPIKIR KRITIS PESERTA DIDIK BERDASARKAN KECERDASAN MAJEMUK DALAM MENYELESAIKAN MASALAH MATEMATIKA
Authors: Rosmiana Farida , Sumadi Suhartini , Pamungkas Dwi
Published: June 2023

Penelitian ini bertujuan untuk mengetahui kemampuan berpikir kritis peserta didik kelas IX A berdasarkan kecerdasan majemuk dengan dominan kecerdasan logis-matematis dan dominan kecerdasan visual-spasial dalam menyelesaikan masalah matematika materi Teorema Pythagoras di MTs. Al-Ma’Arif 1 Kabupaten Sorong. Jenis penenelitian ini menggunakan pendekatan kualitatif deskriptif. Sumber data yang digunakan yaitu data primer. Teknik pengumpulan data dengan cara Tes Kecerdasan Majemuk, Tes Kemampuan Berpikir Kritis, dan Wawancara. Teknik analisis data yang digunukan adalah reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian ini menunjukan bahwa kemampuan berpikir kritis peserta didik dengan dominan kecerdasan logis-matematis dan dominan kecerdasan visual-spasial memenuhi semua kriteria berpikir kritis Focus, Reason, Inference, Situation, Clarity, dan Overview, meskipun ada perbedaan dalam penyelesaiannya.

Kata Kunci : Kemampuan berpikir kritis, Kecerdasan majemuk, Teorema Pythagoras
IMPLEMENTASI GUIDED INQUIRY LEARNING DITINJAU DARI MOTIVASI DAN HASIL BELAJAR SISWA SMP MUHAMMADIYAH AIMAS
Authors: Syamsulrizal Syamsulrizal , Sinaran Herlina
Published: June 2023

Penelitian ini bertujuan untuk mendeskripsikan keefektifan pembelajaran matematika dengan menggunakan guided inquiry learning ditinjau dari motivasi belajar, dan hasil belajar matematika mahasiswa program studi pendidikan matematika.Penelitian ini adalah penelitian eksperimen semu dengan desain pretest-posttest non equivalent control group design. Populasi dalam penelitian ini adalah seluruh siswa SMP Muhammadiyah Aimas. Instrumen yang digunakan adalah soal uraian, angket motivasi belajar, dan lembar observasi. Hasil uji coba instrument penelitian menujukan bahwa soal pretest dan posttes serta angket motivasi reliable dan valid. Hasil analisis data sebelum perlakuan menunjukan bahwa data berdistribusi normal dan homogen. Hasil uji multivariate menunjukan tidak terdapat perbedaan vektor rerata pembelajaran berdasarkan masalah dengan pembelajaran langsung ditinjau dari motivasi dan hasil belajar siswa sebelum perlakuan. Hasil penelitian adalah: 1) Guided Inquiry Learning efektif ditinjau pada aspek  motivasi, dan hasil belajar siswa ; 2) Guided Inquiry Learning lebih efektif dibandingkan dengan pembelajaran konvesional ditinjau pada aspek motivasi, hasil belajar Siswa.
ANALISIS KEMAMPUAN PERSEPSI DAN VISUAL SPASIAL PESERTA DIDIK DALAM MENYELESAIKAN SOAL GEOMETRI BERBASIS OPEN ENDED
Authors: Anggo Ayu Yuniar , Sahidi Sahidi , Syamsulrizal Syamsulrizal
Published: June 2023

Penelitian ini bertujuan untuk mengetahui kemampuan persepsi dan visual spasial Peserta didik kelas IX A dalam pembelajaran Matematika materi Geometri berbasis open ended di MTs Al-Ma’Arif Kabupaten Sorong. Jenis penenelitian ini menggunakan pendekatan kualitatif deskriptif. Sumber data yang digunakan yaitu data primer dan skunder. Teknik pengumpulan data dengan cara Tes, wawancara dan dokumentasi. Teknik analisis data yang digunukan adalah pengumpulan data, reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian ini menunjukan bahwa kemampuan persepsi dan visual spasial peserta didik yang ditinjau dari beberapa indikator. Indikator kemampuan persepsi spasial yaitu : Pengkonsepan dan penyelesaian masalah. Indikator kemampuan visual spasial yaitu : Pengimajinasian dan pencarian pola. Kemampuan persepsi dan visual spasial dapat diperoleh berdasarkan tiga kategori yaitu Tinggi, Sedang, Rendah. Hasil penelitian menunjukan bahwa 1) Kemampuan persepsi dan visual spasial Tinggi dengan nilai 100, 2) kemampuan persepsi dan visual spasial Sedang dengan nilai 81,25, dan 3) kemampuan persepsi dan visual spasial rendah dengan nilai 66,667.
Histomorphological Study of Skin Lesions in a Specialized Tertiary Care Hospital: A Descriptive Study
Authors: Parvez Mashud , Uddin Rukon , Mahmud Salahuddin
Published: June 2023

Introduction: The skin is the largest organ of the integumentary system in human. Dermatological lesions are commonly encountered in all countries and it encompasses a wide spectrum, varies from country to country and various regions within a country. Skin diseases are much common in developing countries. The spectrum varies according to geographic distribution, gender, age, and coexisting disorder. We conducted this study to find out the prevalence of different skin lesions and to evaluate their frequency and site of distribution. Aim of the Study: The aim of this study was to find out the prevalence of different skin lesions and to evaluate their frequency and site of distribution. Methods: This was a descriptive study and was conducted in the Department of Histopathology of Bangladesh Specialized Hospital, Dhaka, Bangladesh during the period from January 2019 to December 2021.We included 133 skin biopsies in our study. Result: Among 133 skin biopsies examined, non-infectious vesicobullous and vesicopustular disease were found in 53 (48.18%) cases followed by microbial disease in 20 (18.18%) and non-infectious erythematous papular and squamous disease in 28 (21.05%) cases. Lichen simplex chronicus was the most common vesicobullous disease seen in 08 (15.09%) cases. Dermatophytes were the commonest microbial disease found in 10 (50%) cases. The commonest non- infectious erythematous papular and squamous disease was lichen planus and psoriasis 08 (15.09%) cases. The commonest neoplastic lesion was keratinocytic tumor seen in 13 (56.53%) cases. The commonest tumor of the skin was seborrheic keratosis and squamous cell carcinoma in 13 (56.53 %) cases. Upper extremities were the most frequently involved site by skin lesions. Conclusion: In our study prevalence of lichen simplex chronicus was higher. We observed a wide spectrum of skin lesions ranging from dermatitis to malignant neoplasm. The importance of specific histomorphological features lies in distinguishing various skin lesions and play a major role in making the final diagnosis of these diverse skin lesions. This highlights the role of histopathological examination for the proper management of patient.
The Influence of Digital Marketing, Access to Capital, and Financial Management on the Competitiveness of MSMEs Products in the Regency/City of Tasikmalaya
Authors: Putri Mega Amalia , Hanida Tiara , Tarwisah Iyang Siti , Wati Vera , Maulana Zidan Arif , Firmansyah Irman
Published: June 2023

Micro, Small and Medium Enterprises or MSMEs have proven to be the spearhead of the Indonesian economy at the national, regional, and regional levels, including in the Regency/City of Tasikmalaya. The sustainability of MSMEs is a success in business ventures. This can be seen from the digital marketing strategy, financial management, and access to capital, which are the determining factors for the competitiveness of MSMEs products. This study aims to determine the effect of digital marketing, access to capital, and financial management on product competitiveness in Tasikmalaya Regency/City. It can be used as supporting and evaluation material in planning activities and policy planning, increasing MSMEs product competitiveness in Tasikmalaya Regency/City. The research method used quantitative research using a questionnaire instrument distributed to MSMEs actors in the Tasikmalaya Regency/City with 74 respondents. The data analysis technique used is multiple linear regression with the help of the SPSS program. The study results show that digital marketing, access to capital, and financial management positively affect product competitiveness in Tasikmalaya Regency/City.
Strategic planning in Gauteng grassroots football clubs
Authors: Boya Kgaugelo Sammy , Venter Peet
Published: June 2023

Strategic planning has become indispensable for organisations that seek to develop and grow, and grassroots football clubs are no exception. As large amounts of money are invested in football clubs, these entities may be prone to substantial financial risk if resources are not effectively deployed, underlining the importance of strategic planning and management. Against this background, this qualitative study explored the strategic planning processes of grassroots football clubs in Gauteng Province, South Africa. Interviews were conducted with representatives of 12 football clubs affiliated with the South African Football Association, and data were analysed thematically. The findings suggest that grassroots football clubs are like not-for-profit community organisations in their strategic planning approach (or lack thereof). Grassroots football clubs still have much to do in developing their strategic planning capabilities to create value and enhance the sustainability of football.
Short-term effect of Kinesiotape™-application on running speed, agility and plyometric performance in amateur soccer players
Authors: Cochrane Maria Elizabeth , Nkuna Felix , Dawood Muhammad
Published: June 2023

Soccer is a physically demanding team sport requiring players to run fast, perform multiple changes in direction and jump, among other skills. Soccer players with optimal running speed, agility and plyometric abilities are more likely to be selected for team participation, as they will have enhanced on-the-field performance. Various exercise and rehabilitation protocols exist to ensure optimal player performance, but none focus on the immediate effect of Kinesio tape (Kinesio Holding Corporation, Albuquerque, NM, USA) on the stabilising muscles of the lower limb to influence important basic soccer skills. A one-group pre-test–post-test quasi-experimental design was used. Thirty-three male university-level soccer players aged 18–35 years with no history of lower limb surgery were included. Baseline testing was performed using the vertical jump test, Modified Illinois Change of Direction test and a timed 50-metre sprint. After a rest period of 1–4 days, the participants were strapped with Kinesio tape and the post-test, using the same objective measures, was conducted. Pre- and post-test analysis was performed using paired student t-test. Improvement was observed for running speed (p≤0.001, SD: 0.685), agility (p≤0.001; SD: 2.312) and plyometrics (p≤0.001; SD: 2.451). The application of Kinesio tape on the stabiliser muscles of the lower limbs significantly improved running speed, agility and plyometrics in amateur soccer players immediately after application.
مِنْ أَمْثِلَةِ ابْنِ مَالِكٍ فِي الألفيَّة لِتَوضِيحِ القَاعِدَةِ النَّحوِيَّةِ
Authors: أ.م.د. أبو حنيفة عمر الشريف علي عمر
Published: June 2023

يُعَالِجُ البَحثُ بَعْضَ أَمْثلةِ ابنِ مالك في ألفيَّتهِ المُتَضمِّنَة القواعد الأساسيَّة للأبواب النَّحويَّة الواردة فيها؛ لإثبات رؤوس القواعد النَّحويَّة ودراستها دلاليًّا، رابطًا ذلك بِمَا ورد في الكُتبِ النَّحويَّة، مع بيانِ إفادةِ شُرَّاح الألفيَّة من هذه الأمثلة في شُرُوْحِهِم، وقد أتتْ أهميَّةُ هذا الموضوع في كونهِ يُلقي الضّوء على موضوعٍ مُهِمّ، وهو: دراسة أمثلة ابن مالك في الألفيَّة نحويًّا ودلاليًّا، ومن أهدافِ البَحثِ التي سَعَى إلى تحقيقها: الوقوف على أمثلة ابن مالك في الألفيَّة لإثبات القاعدة النَّحويَّة، ولطبيعة البحث اُنتهج فيه المنهج الوصفي، وأُخذ من أدواته التَّحليل، وقد جُعِلَتْ حدوده الأمثلة المَالكيَّة في خلاصَتِهِ النَّحويَّة، ودراستها نَحويًّا، ودلاليًّا؛ وقد قًسِّمَ البحث إلى محورين، اهتمَّ الأوَّلُ منهما بالتَّعريف بابن مالك وألفيته، واختصَّ الآخر بالحديث عن مفهوم الأمثلة، ودراسة بعض أمثلة ابن مالك في ألفيَّته دراسة نحوية دلاليَّة، ثُمَّ خاتمة ذُكِرَ فيها أهمّ ما تَوَصَّلَ إليه البَحثُ من نتائج وتوصيات.
فاعلية برنامج علاجي معرفي سلوكي لخفض التعب العصبي لدى أمهات الاطفال ذوي الشلل الدماغي
Authors: أ.م. د. رنا عبد المنعم كريم العباسي
Published: June 2023

يعد العلاج المعرفي السلوكي من أهم البرامج العلاجية الحديثة نسبياً والتي تحاول تعديل السلوك والتحكم في الاضطرابات النفسية من خلال تعديل أسلوب تفكير الفرد وإدراكه لنفسه وبيئته، وإعادة البناء المعرفي من خلال استبدال الأفكار السلبية بأخرى إيجابية. هدفت الدراسة الحالية الى تعرف فاعلية برنامج علاجي معرفي سلوكي في خفض التعب العصبي لدى أمهات الاطفال ذوي الشلل الدماغي، تكونت العينة التي طبق عليها مقياس التعب العصبي من (30) أم يعاني ابنها الشلل الدماغي وأشارت النتائج الى ان (24) أم تعاني التعب العصبي. تم تقسيم هذه العينة الى مجموعتين المجموعة الأولى التي طبق عليها البرنامج العلاجي وهي العينة التجريبية وكان عدد افرادها (12) أم والمجموعة الثانية وهي المجموعة الضابطة والتي تكونت من (12) أم. واشارت النتائج الى فاعلية البرنامج العلاجي معرفي السلوكي لخفض التعب العصبي لدى أمهات الأطفال ذوي الشلل الدماغي، وكانت هنالك مجموعة من التوصيات التي تساعد الأمهات.