bluuebunny/crossref_metadata_2025 huggingface dataset:
Radiomics Derived Brain Age Predicts Functional Outcome After Acute Ischemic Stroke
Authors: Bretzner Martin , Bonkhoff Anna , Schirmer Markus , Hong Sungmin , Dalca Adrian , Donahue Kathleen , Giese Anne-Katrin , Etherton Mark , Rist Pamela , Nardin Marco , Regenhardt Robert , Leclerc Xavier , Lopes Renaud , Gautherot Morgan , Wang Clinton , Benavente Oscar , Cole John , Donatti Amanda , Griessenauer Christoph , Heitsch Laura , Holmegaard Lukas , Jood Katharina , Jiménez-Conde Jordi , Kittner Steven , Lemmens Robin , Levi Christopher , McArdle Patrick , McDonough Caitrin , Meschia James , Phuah Chia-Ling , Rolfs Arndt , Ropele Stefan , Rosand Jonathan , Roquer Jaume , Rundek Tatjana , Sacco Ralph , Schmidt Reinhold , Sharma Pankaj , Slowik Agnieszka , Sousa Alessandro Viana Oliveira e , Stanne Tara , Strbian Daniel , Tatlisumak Turgut , Thijs Vincent , Vagal Achala , Wasselius Johan , Woo Daniel , Wu Ona , Zand Ramin , Worrall Bradford B. , Maguire Jane , Lindgren Arne , Jern Christina , Golland Polina , Kuchcinski Grégory , Rost Natalia
Published: September 2021

While chronological age is one of the most influential determinants of post-stroke outcomes, little is known of the impact of neuroimaging-derived biological brain age. We here first examine whether radiomics analysis of the texture of brain T2-FLAIR MRI images can be used to predict brain age in stroke patients. We then assess the clinical determinants of accelerated brain aging and, finally, its impact on post-stroke functional outcomes. Leveraging a multisite cohort of 4,163 ischemic stroke patients, we show that older-appearing patients have more hypertension, diabetes mellitus, prior strokes, and smoking history and are more likely to develop worse post-stroke outcomes than their younger-appearing counterparts. Our results strengthen the importance of preventive medicine for maintaining brain health in stroke patients as they age and suggest a novel methodology to capture previously undescribed prognostic information available on commonly acquired MRI sequences during routine stroke care.
Low-Profile Visualized Intraluminal Support Stent for the Endovascular Treatment of Traumatic Internal Carotid Artery Pseudoaneurysms
Authors: Tan Song , Zhou Xiaobing , Lu Yuzhao , Lai Lingfeng , Huang Xiaofei , Li Bin , Wang Yang
Published: September 2021

Objectives Optimal treatment strategies for traumatic internal carotid artery (ICA) pseudoaneurysms are controversial. The low-profile visualized intraluminal support (LVIS) device is a braided stent with a metal coverage rate between traditional laser cut stents and flow diversion devices. We report here our therapy strategy using the LVIS stent-assisted coiling for treatment of traumatic ICA pseudoaneurysms.Methods Patients with traumatic ICA pseudoaneurysms treated by the LVIS stent-assisted coiling in our center between January 2015 to June 2021 were reviewed. The complications, radiographic, and clinical outcomes of these patients were analyzed.Results A total of 12 pseudoaneurysms in 12 patients were included. Immediate postoperative angiogram showed that six (50%) aneurysms were Raymond grade 1, four (33.3%) were grade 2, and two (16.7%) were grade 3. Two patients with severe primary cranial injury discontinued treatment after the procedure. During the follow-up of the other ten patients, two patients (20%) received additional coiling because of recanalization of the pseudoaneurysm. At the last angiographic follow-up examination, all aneurysms were Raymond grade 1. Postoperative multiple cerebral infarction occurred in two patients. Of the ten patients with a mean clinical follow-up of 32.2 ± 27.9 (median, 18) months, eight patients recovered well, one patient had right hemiplegia, and one patient died of airway damage, which was unrelated to the pseudoaneurysm.Conclusions LVIS stent-assisted coiling was a feasible approach for the treatment of traumatic ICA pseudoaneurysms.
Anticoagulant therapy in elderly patients with atrial fibrillation : A time series study using the nationwide claim database in Japan
Authors: Tsuji Noriko , TAKAHASHI Yoshimitsu , Sakai Michi , Ohtera Shosuke , Kaneyama Junji , Cho Kosai , KATO Genta , Ohtsuru Shigeru , Nakayama Takeo
Published: September 2021

Background and aim: The introduction of direct oral anticoagulants (DOACs) has greatly changed the use of anticoagulant therapy in patients with non-valvular atrial fibrillation (Af). However, few studies have reported on the current state of anticoagulant therapy at the national level. This study aimed to examine changes in the proportions of oral anticoagulant (OAC) prescriptions (4 DOACs and a vitamin K antagonist: VKA) in patients with non-valvular Af aged ≥65 years, taking into consideration the risk of cerebral infarction and bleeding.Methods: Anticoagulant prescriptions in outpatients with Af were temporally analyzed using the nationwide claims database in Japan. The proportion of anticoagulants prescribed to Af patients aged ≥65 years was determined. Trends in anticoagulant prescriptions were examined according to cerebral infarction and bleeding risk.Results: The proportion of anticoagulant prescriptions for 12,076 Af patients aged ≥65 years in Japan increased from 41% in 2011 to 56% in 2015. The proportion of prescriptions for DOACs surpassed that of VKA. An increase in DOAC prescriptions was accompanied by an increase in the proportion of anticoagulant prescriptions in each group according to the CHA2DS2-VASc and HAS-BLED scores. The proportion of anticoagulant prescriptions for patients with a high risk of developing cerebral infarction and bleeding showed a marked increase.Conclusion: Trends in anticoagulant prescriptions in patients with non-valvular AfAf in Japan showed a marked increase in DOAC prescriptions. The widespread use of DOACs greatly changes the profiles of cerebral infarction and bleeding risks, which are related to the prescription of anticoagulant therapy in patients with non-valvular Af.
Influence of phosphorus fertiliser blend on grain yield, nutrient concentration, and profitability of soyabean in the Southern Guinea Savanna of Ghana
Authors: Adjei-Nsiah Samuel , Ahiakpa John Kojo , Gyan Kwesi , Kanampiu Fred
Published: September 2021

We conducted on-farm trials in the southern Guinea Savanna of Ghana in 2016 and 2017 to evaluate soyabean response to three fertiliser blends to guide farmers towards profitable adoption of appropriate phosphorus (P) fertiliser blend for improved soyabean production. Old YARA Legume (OYL), New YARA Legume (NYL) and Triple Superphosphate (TSP) fertiliser blends were evaluated. In both years, the P fertiliser blends were evaluated in a Randomised Complete Block Design with 20, 30, and 40 kg P ha-1 application rates together with control. P fertiliser application increased soyabean yields by 1070 kg ha-1. In 2016, fertiliser blend use efficiency (BUE) ranged from 2.9 kg grain per kg fertiliser blend applied with the NYL applied at 40 kg P ha-1 to 7.4 kg grain per kg fertiliser blend applied with the TSP applied at 40 kg P ha-1 with significant differences between treatments. In 2017, BUE ranged from 2.5 kg grain per kg fertiliser blend applied with OYL applied at 40 kg P ha-1 to 9.2 kg grain per kg fertiliser blend applied with the TSP applied at 40 kg P ha-1 with significant differences between treatments. However, P use efficiency did not significantly differ between the different treatments both in the 2016 and 2017 trials. In both 2016 and 2017 trials, the highest benefit cost ratio was attained at the lowest application rate for all the three fertiliser blends suggesting the need to review the current application rate of 30 kg P fertiliser ha-1 promoted in northern Ghana. Furthermore, the provision of credit and/or subsidy for farmers by the government is required to enable uptake and utilisation of fertilisers by farmers.
Closure of Oronasal Fistulae Post Palatoraphy with Tongue Flap in Bilateral Complete Cleft Lip Palate Patient: A Case Report
Authors: Sayekti Menik , Barus Liska , Sumarta Ni Putu Mira , Nakamura Norifumi
Published: September 2021

Oronasal fistulae are common complication following palatoraphy. There are several surgical procedures to repair oronasal fistulae. However, conventional oronasal fistulae closure technique is not always possible, especially when the surrounding tissue is replaced by fibrotic tissue due to previous palatoraphy. Tissue defects in oronasal fistulae should be replaced with tissues providing good vascularisation such as pedicle tongue flap. A case of pedicle tongue flap used to close oronasal fistulae was reported. Eleven-year-old girl, presented with oronasal fistulae and bilateral alveolar cleft after previous palatoraphy. The oronasal fistulae were closed with pedicled tongue flap. The healing was uneventful, and the division of the pedicle tongue flap was done three weeks later and closed primarily. There was no dehiscence of the wound and masticatory functions were recorded. Vascularised flap such as pedicle tongue flap is a preferred technique to close oronasal fistulae after palatoraphy.
One-piece Implant Placement as an Alternative and Acceptable Treatment for Missing Tooth Rehabilitation: A Case Report
Authors: Teguh Paulus Budi , Nanik Chaterina Diyah
Published: September 2021

Currently dental implant treatment become popular. More clinicians are being presented with the opportunity to perform implant services in their own practice. The use of one-piece implant can be considered as treatment for the replacement of missing tooth in the areas of limited tooth-to-tooth spacing and would bring less trauma for the soft tissue. A 52-year-old female patient presented with difficulty in mastication due to the loss of teeth of 35 region with limitation mesio distal space. Radiology examination did not reveal any radiolucencies in 35 region. Radiograph revealed sufficient bone height from crestal to the floor of the mandible. A one-piece implant was placed in the 35 region. The present case used an endosteal implant, one stage surgery, and delayed loading. Restoration with porcelain fused to the metal crown had been delivered three months after the one-piece implant placement. The result of this treatment indicated that one-piece implant could be considered as an effective therapy choice for replacement of missing tooth in order to rehabilitate the masticatory function.
Antibacterial Effectiveness of Calcium Hydroxide Combined with Cresotin against Enterococcus faecalis
Authors: Aprilia Aprilia , Kusuma Belinda , Wardani Istien
Published: September 2021

The goal of endodontic treatment is to prevent and control of pulp and periradicular infections. Calcium hydroxide has a beneficial biological property as an intracanal medicament and can be combined with cresotin to disinfect bacteria in root canals, especially Enterococcus faecalis (E. faecalis) which is the most frequently isolated strain in the root canals. The aim of this study was to investigate in vitro the antimicrobial activity of calcium hydroxide, cresotin, and combination calcium hydroxide and cresotin (Ca[OH]2+Cresotin, 1:1 and 1:2) against E. faecalis. Antibacterial activity was determined by the agar diffusion method. The test medicaments were placed inside the hole that made in the inoculated agar medium. The zone of growth inhibition was measured and recorded after incubation for each plate, and the result was analysed statistically with ANOVA. The in vitro antimicrobial effects of combination calcium hydroxide and cresotin (Ca[OH]2+Cresotin, 1:2) has more prominent antimicrobial activity than others, and calcium hydroxide is more effective than cresotin alone. The antimicrobial activity of combined calcium hydroxide and cresotin is more effective in killing E. faecalis in comparison to the other treatments.
Acanthus ilicifolius L. Treatment for Oral Candidiasis with Immunosuppressive Conditions Subjected to p38 MAPK Enhancement
Authors: Andriani Dwi , Pargaputri Agni Febrina , Parisihni Kristanti , Revianti Syamsulina
Published: September 2021

Methanolic extract from the leaves of Acanthus ilicifolius L. (A. ilicifolius L.) is a potent inhibitor of Candida albicans (C. albicans) growth and anti-inflammatory. C. albicans causes oral candidiasis in immunosuppressive condition. Mitogen-activated protein kinase (MAPK) signalling via p38 appears to discriminate between yeast and hyphal cells of C. albicans. Activation of p38 MAPK by hyphae results in the upregulation of proinflammatory cytokines. The p38 MAPK activation is known to impair corticosteroid action. The research was conducted to investigate the effect of methanolic extract A. ilicifolius L. treatment of oral candidiasis with the immunosuppressive condition through enhancement of p38 MAPK expression in the epithelial cells. Immunosuppressed conditions were obtained when 16 healthy male Rattus norvergicus (Wistar) was given oral administration of dexamethasone and tetracycline for 14 days and induced with C. albicans (ATCC-10231) 1 McFarland. The subjects were divided into four groups (n = 4/group): immunosuppression (IS), immunosuppression with oral candidiasis without treatment (ISC), immunosuppression with oral candidiasis and nystatin treatment (ISC+N), and immunosuppression with oral candidiasis and A. ilicifolius L. treatment (ISC+AI), and were treated for 14 days. Later, the rats were euthanised, and their tongue were biopsied. The p38 MAPK expression was subjected to immunohistochemical examination, observed under a microscope (400× magnification) and statistically analysed (one-way ANOVA, LSD-test, p < 0.05). The p38 MAPK expression of ISC+AI (36.05 ± 1.54) was higher than IS (26 ± 2.32), ISC (26.4 ± 3.71), IS+N (34.2 ± 0.99). Significant differences existed between ISC+AI and ISC+N to IS and ISC (p < 0.05). No significant differences were present between IS and ISC; ISC+AI and ISC+N (p > 0.05). Therefore, this treatment could enhance p38 MAPK expression in oral candidiasis with the immunosuppressed condition.
Efficient Tuning of Hyper-parameters in Convolutional Neural Network for Classification of Tuberculosis Images
Authors: Arora Ruchika , Saini Indu , Sood Neetu
Published: September 2021

Deep Learning (DL) algorithms, especially Convolutional Neural Network (CNN) have outperformed in medical image classification tasks and have achieved human-competitive performance. This has become possible because CNN learns image features through backpropagation. However, the strategy for designing a CNN model with the highest accuracy for a specific application is often unclear. Because finding an appropriate network structure with the best combination of hyperparameters for different datasets is always a challenging task. To address this, we propose an optimized CNN framework that automatically and efficiently tune its hyper-parameters using a hyperband search optimization approach. In this paper, an efficient CNN with optimized hyperparameters for the classification of tuberculosis disease in Chest X-Ray (CXR) images is trained and tested on a publicly available NLM-China dataset. The experimental results illustrate that the hyperparameters optimize the CNN framework and achieve 91.42% accuracy for the classification of tuberculosis disease in CXR images.
Real Time Smartphone Data for Prediction of Nomophobia Severity using Supervised Machine Learning
Authors: Arora Anshika , Chakraborty Pinaki , Bhatia M.P.S.
Published: September 2021

Excessive use of smartphones throughout the day having dependency on them for social interaction, entertainment and information retrieval may lead users to develop nomophobia. This makes them feel anxious during non-availability of smartphones. This study describes the usefulness of real time smartphone usage data for prediction of nomophobia severity using machine learning. Data is collected from 141 undergraduate students analyzing their perception about their smartphone using the Nomophobia Questionnaire (NMP-Q) and their real time smartphone usage patterns using a purpose-built android application. Supervised machine learning models including Random Forest, Decision Tree, Support Vector Machines, Naïve Bayes and K-Nearest Neighbor are trained using two features sets where the first feature set comprises only the NMP-Q features and the other comprises real time smartphone usage features along with the NMP-Q features. Performance of these models is evaluated using f-measure and area under ROC and It is observed that all the models perform better when provided with smartphone usage features along with the NMP-Q features. Naïve Bayes outperforms other models in prediction of nomophobia achieving a f-measure value of 0.891 and ROC area value of 0.933.
Design of Low Power Neuro-amplifier Circuit with Miller Compensation Technique for Biomedical Neuro-implantable Devices
Authors: Dwivedi Kriti , Gupta Aparna , Oberoi Ritika , Mathew Ribu
Published: September 2021

Neuro-amplifiers form an integral part of biomedical implantable devices. In this paper, we design a neuro-amplifier circuit with Miller compensation capacitor. The neuro-amplifier design is based on operational transconductance amplifier (OTA) with an active load. In this work, performance of the neuro-amplifier is enhanced by incorporating the Miller compensation technique. Design and simulation of the neuro-amplifier circuit is performed using SPICE simulation software. Body biasing and feedback techniques are imparted to optimize the circuit performance. Simulation results show that the neuro-amplifier circuit has a mid-frequency gain and 3-dB bandwidth of 48dB, and 16kHzrespectively.
Cardiovascular and Cardiorespiratory Signals Complexity Analysis Using Different Techniques
Authors: Singh Kirti , Saini Indu , Sood Neetu
Published: September 2021

In recent decades, the concept of complex physiological systems has become more and more popular. The evaluation of the biological time series' dynamic complexity is an essential subject with possible applications such as the characterization of physiological states i.e. HRV, BP, and RESP signals and pathological disorders to the measurement of diagnostic parameters. The convergence of several physiological regulation processes is the cause of heterogeneity in cardiovascular time series, that consider many factors and function over several time scales, resulting not only the presence of short-term dynamics but also the coexistence of long-range correlations in various physiological signals. The most popular approach to evaluating the dynamic complexity and irregularity of time series over multiple time scales is entropy based analysis. The most used approach is multiscale entropy (MSE) and refined MSE (RMSE). It is then added to the heart period time series, respiration time series, and blood pressure time series, measured in young subjects and old subjects under resting conditions. This research applies to short-term cardiovascular and cardiorespiratory variability documents that LMSE can better describe physiological processes' behavior causing biological oscillations at various time scales than RMSE.
A Review on Evolution Trends in Passive Optical Networks
Authors: Kaur Ramandeep , Singh Simranjit
Published: September 2021

In this paper, the passive optical network (PON) evolution trend has been discussed. The literature of PON standards which are ATM PON (APON), Broadband PON (BPON), Gigabit PON (GPON), 10-Gigabit-capable passive optical networks (XG-PON) and next-generation PON2 (NG-PON2) has been reviewed extensively. From the literature review, a comparison of the PON technologies is made. The GPON, XG-PON and NG-PON2 are the most recent PON generations, and these are simulated to find the split per wavelength supported. The Q-factor below 6 is considered unacceptable in the analysis. The results show that the GPON can support 32 ONU when transmitted power set to 3dB. In the case of XG-PON, the Q-factor remains more than 6 for a split ratio up to 16. For the NG-PON2, the observed Q-factor is more than 6 for split up to 32. However, as the split increases above 32, the Q-factor falls below the acceptable level of 6.
A Brief Review of Energy Efficient Protocols in Mobile Ad hoc Networks
Authors: Kaur Kirandeep , Kaur Satinder
Published: September 2021

Mobile Ad Hoc Networks (MANETs) is an assemblage of multi-hop wireless mobile nodes that communicate with each other without centralized control and established infrastructure. Energy efficient routing is not merely concerned about less power consumption, it also deals with increasing the time duration in which any network maintains certain performance level. Therefore, power management becomes an essential issue. Considering this, various authors have designed and developed different techniques to enhance the energy efficiency of mobile networks. This paper focuses on the comparative study of different developments and modifications that have been carried out in this field in past decades. It also highlights how these modifications have helped to enhance the network lifetime.
Geospatially Enabled Serious Gaming for Decision Support in Agroforestry System: A Conceptual Study
Authors: Khan Nadeem Ahmad , Khosla Arun , Singh Parampreet
Published: September 2021

Natural resources are in a constant state of depletion. The main reason being over exploitation of these resources and not contributing to their replenishment. To deal with these challenges, ecologists, leaders and experts have recommended the adoption of an agroforestry agriculture system. Agroforestry is more sustainable agricultural method that provides a long term vision to combat food insecurity. In spite of agroforestry being very useful, still individuals can not foresee it’s advantages. Serious games can motivate people in agroforestry scenarios and involve users in high interaction. GIS is a tool that can help in decision of proper location for agroforestry depending upon past data or information available. This paper defines a conceptual study for serious game to dynamically create 3D real-world agro-forestry environments. The serious games aim to provide visualization, intuitive management, and analysis of geospatial, hydrological and economic data to help participants for the decision support in agroforestry systems.
An Analysis of Heuristics for a Mathematically Incomplete Variant of TicTacToe
Authors: Baker Feyaz , Mukhoti Arunava , Chandavarkar B. R.
Published: September 2021

We attempt to produce a game-winning heuristic for the mathematically incomplete game Ultimate Tic Tac Toe (UTT). There are several game AI that use Monte Carlo Tree Search to decide moves, however, heuristics offer a faster and computationally cheaper alternative. The mathematical analysis of UTT has not been actively pursued, so we attempt to prove a posteriori. We have decided on a few strategies for playing, and assign different strategies to each player. We play several automated games of UTT, and statistically analyse which games end quickest, and use that data to find optimal strategies for playing. This can be used to produce game heuristics for more complicated games, and produce insight about strategies. The first objective is to specify a framework that can compare heuristics for UTT, and decide an optimal strategy for both players. The second objective is to test the framework with a large amount of data, and produce demonstrable results for UTT. Lastly, to aid further research in this topic, we release our dataset into the public domain.
A Temperature-Dependent Threshold Voltage Model for SiGe Source/Drain Si–NT JLFET
Authors: Thakur Anchal , Dhiman Rohit
Published: September 2021

In this paper, we investigate the impact of temperature on threshold voltage in the SiGe source/drain silicon-nanotube junctionless field effect transistor (NT JLFET). A threshold voltage model has been derived with inclusion of temperature for presented device. It is found that when the temperature increases from T = 300 K, T = 400 K, and T = 500 K, the strain produced by the SiGe source/drain on channel has been relaxed. However, the elevated temperature decreases the potential and the electric field in channel due to increases in intrinsic carrier concentration which further shifts the Fermi level towards the band gap. It has been evaluating that the threshold voltage roll-off and the short channel effects increases due to increases in temperature. The numerical results of threshold voltage model have been well compared with results of 2-D technology computer aided design (TCAD) simulations.
Design of Constant Transconductance Operational Amplifier By CMOS With High Gain And Low Operational Power
Authors: Kumar Parvesh , Chaudhary Tarun , Ram Vijay Kumar
Published: September 2021

In the following paper, there is a presentation of a small potential, small capacity CMOS which programs numerically working trans conductance circuit of an amplifier (OTA). A constant transconductance up to (7% of max variation) secures the whole usual-mode of the input range. The circuit process and it can also be operated on a voltage supply of 3.3V with a common-mode range of input from 0.3 to 1.6V. A constant-current is maintained by the designed OTA and also provide a continuous transmission capacity for varying burden capacitors with no increase in consumption of capacity. Simulation of the circuit works upon T-SPICE .5 µm level 49 sub-micron technology.
Design and Analysis of a Dual Material Triple Gate TFET with the Pocket Doping for the Performance Enhancement
Authors: Gupta Rahul , Khosla Mamta , Wadhwa Girish
Published: September 2021

In this investigated work, we have analysed the miscellaneous figure of merit for Double metal Triple gate TFET. Various techniques have been utilized to improve the ON-state driven current in the drain by doing a comprehensive analysis. Different techniques are examined and correlated by using the TCAD Silvaco tool to get excellent ON current. Further work function engineering has been done in the optimized DMTG-TFET to increase its performance and finally, we introduce pocket doping that increases the ON current (2.34×10-3) and also ION/IOFF ratio (4.36×1014) with subthreshold (SS) of 25.8mV/decade. The pocket doped DMTG-TFET adequately suppress the ambipolarity and endeavour about 20 times higher ION as compared to conventional DMTG-TFET.
Índice de Temperatura y Humedad (THI) respaldado por el Cortisol Capilar en ganado lechero para la medición de Estrés Calórico Crónico
Authors: López-Quiñonez Edna , Albarrán-Tamayo Froylán , Ramírez-Emiliano Joel , Bañuelos-Hernández Bernardo , Cruz-Hernández Andrés
Published: September 2021

Introducción: El estrés crónico en el ganado bovino lechero es uno de los mayores problemas para la producción de leche ya que reduce la producción, aumentan las enfermedades y se reproducen menos y el principal causante es el clima. El estrés calórico ha sido estudiado por muchos años, pero el parámetro más comúnmente usado es el índice de temperatura y humedad (THI), este proviene de las mediciones meteorológicas y no de los cambios que ocurren en el organismo de la vaca.
Método: Para encontrar la relación entre el THI y la respuesta del organismo ante el estrés, muestreamos bimestralmente pelo de 50 vacas Holstein de un establo lechero intensivo automatizado durante un año, extrajimos el cortisol acumulado y lo medimos mediante la técnica de ELISA. También se obtuvieron las mediciones climatológicas de los reportes meteorológicos locales para calcular los THI y los promedios de cada periodo. Mediante un análisis de regresión múltiple se calculó la correlación de las concentraciones bimestrales de cortisol con los promedios de temperatura, humedad, viento y THI en los mismos periodos.
Resultados: Los cambios en los niveles de cortisol de cada periodo fueron significativamente diferentes al anterior. El análisis de regresión múltiple mostró como principal regresor al THI (p < 0.001).
Discusión: Los resultados mostraron que el THI está significativamente relacionado con los niveles de cortisol capilar, esto demuestra que el THI es un parámetro confiable, si no para calcular el estrés fisiológico, sí para saber indirectamente el estrés que puede provocar el clima y tomar decisiones en las explotaciones de ganado lechero.
Models for the concept implementation of “smart city”: analysis of European experience
Authors: Kostko Natalya A.
Published: September 2021

The appeal to cities is determined by their significance and role in the modern world. The vector of urban development depends on various factors, but is directly related to the modern type of society and the choice of the governance model by the authorities. In essence, each of the city models development management correlates with the theories of economic growth, new urbanism and includes all or individual elements of the concepts: sustainable development, healthy, inclusive, entrepreneurial, smart, creative cities. All these concepts are united by the task of identifying additional resources, conditions and grounds for the development of cities. The purpose of this article is to analyze the European experience in implementing the concept of a creative city. Today, there are several management models for the concept implementation of “smart city” with an emphasis on creative industries, which differ in the structure and composition of sectors, the definition of priority among them. In European urban management policy, creative industries are identified as a socio-economic factor and driver of the city’s success. New in this article is the emphasis on sociality in choosing a model for the concept implementation with the need to pair it with the concept of a “smart city”. An analysis of European experience shows that each of the countries, in accordance with national specifics, uses its own model of the functioning of creative industries in cities, which must be done in our country as well. The contribution of creative industries to the development of cities is not only economic, but also social, which is the merit of the concept.
Multilocular Thymic Cyst with Superior Cava Vein Syndrome Complication
Authors: Widodo Rahadi
Published: September 2021

Background: Thymic cysts are uncommon, only comprising 1-3% of all mediastinal masses and 5-28% of the mediastinal cysts. Usually benign entities representing remnants of persistent thymopharyngeal duct or cystic degeneration of Hassall corpuscles. Unilocular thymic cysts are probably of congenital origin (derived from embryologic thymic tissue) and without inflammation, while multilocular thymic cysts are predominantly acquired, resulting from inflammation or neoplasm, have thick walls and contain dark-brown fluid.Case: A 51-year-old male with complaint of pain on his neck, shoulder, and right chest, accompanied with swelling of right arm and vena ecstasis on his neck and chest wall. The patient was diagnosed as anterior mediastinal tumor with complication vena cava superior syndrome. He underwent surgical treatment with approach median sternotomy and wide excision of tumor. Histopathologic examinaton of the tumor reveals a multilocular thymic cyst. Pneumonia occured after surgery and could be overcome by aggresive combination antibiotic treatment. There was right pleural effusion and right phrenic nerve paralysis after surgery. In this patient, also there is a mass in right posterior pleural cavity which has not been removed by surgical treatment.
Successful Therapy on Patients with Yolksac and Embrional Carcinoma by Surgery and Chemotherapy
Authors: Prasetya Fahmi Adhi , Djajalaksana Susanthy , Retnani Diah Prabawati , Isharanto Artono , Normahayu Indrastuti , Okta Shinta
Published: September 2021

Background: Malignant mixed germ cell tumors account for 13-25% of all non seminoma germ cell tumors, almost all cases were found in males (85%), increased in the third decade, and had an average survival rate of 40-45%. With modern management the average 5-year survival rate can be over 80%.Case Report: We reported a case report in Saiful Anwar Malang Hospital, Indonesia, a young man, 26 years old with an malignant epithelial tumor derived from mediastinal or lung. The CT scan of the chest showed an lobulated solid mass of iso-hipodens on the anterior superior mediastinum, mass encompassing the aortic arch, left pulmonalis artery, subclavian artery. The result from transthoracic FNAB with USG guidance showed an malignant epithelial tumor derived from mediastinal or lung, impression of an adeno squamous carcinoma. The AFP, LDH, and NSE serum level was elevated. Patient underwent a surgical sternotomy and tumor debulking. The biopsy showed an malignant mixed germ cell tumor (yolksac and embrional carcinoma). These were confirming the diagnosis of malignant mixed germ cell mediastinal tumor (yolksac and embrinonal carcinoma). Patient received a combination bleomycin, etoposid, cisplatin 3 series chemoteraphy Â and evaluated.Conclusion: Some procedures like biopsy, tumor marker, could differentiate the subtype of mediastinal germ cell tumor. The multimodality treatment by combining surgical therapy (surgical sternotomy and tumor debulking) with chemotherapy could increase the survival rate of patients.
Diseño y construcción de prototipos de heliodón para simulador de trayectorias solares
Authors: García-Quintero Thadee Birzavitt , Morales-Guzmán Carlos César
Published: September 2021

Se presenta el desarrollo y funcionamiento de dos modelos de simuladores de trayectorias solares (Heliodón) y su aplicación en la Arquitectura. Se observa el impacto de las sombras sobre una vivienda y la orientación correcta del proyecto utilizando estos prototipos. El proceso de diseño y construcción del Heliodón permite aprovechar al máximo la incidencia solar en la Arquitectura y otorgarle a las viviendas un menor consumo energético, a fin de disminuir la afectación al medio ambiente.
Active Annotation in Evaluating the Credibility of Web-Based Medical Information: Guidelines for Creating Training Data Sets for Machine Learning
Authors: Nabożny Aleksandra , Balcerzak Bartłomiej , Wierzbicki Adam , Morzy Mikołaj , Chlabicz Małgorzata
Published: September 2021

Background

The spread of false medical information on the web is rapidly accelerating. Establishing the credibility of web-based medical information has become a pressing necessity. Machine learning offers a solution that, when properly deployed, can be an effective tool in fighting medical misinformation on the web.

Objective

The aim of this study is to present a comprehensive framework for designing and curating machine learning training data sets for web-based medical information credibility assessment. We show how to construct the annotation process. Our main objective is to support researchers from the medical and computer science communities. We offer guidelines on the preparation of data sets for machine learning models that can fight medical misinformation.

Methods

We begin by providing the annotation protocol for medical experts involved in medical sentence credibility evaluation. The protocol is based on a qualitative study of our experimental data. To address the problem of insufficient initial labels, we propose a preprocessing pipeline for the batch of sentences to be assessed. It consists of representation learning, clustering, and reranking. We call this process active annotation.

Results

We collected more than 10,000 annotations of statements related to selected medical subjects (psychiatry, cholesterol, autism, antibiotics, vaccines, steroids, birth methods, and food allergy testing) for less than US $7000 by employing 9 highly qualified annotators (certified medical professionals), and we release this data set to the general public. We developed an active annotation framework for more efficient annotation of noncredible medical statements. The application of qualitative analysis resulted in a better annotation protocol for our future efforts in data set creation.

Conclusions

The results of the qualitative analysis support our claims of the efficacy of the presented method.
Authors’ Response to Peer Reviews of “Technologies to Support Assessment of Movement During Video Consultations: Exploratory Study” (Preprint)
Authors: Jones Ray B , Hubble Suzanne , Taylor Lloyd , Gunn Hilary , Logan Angela , Rowland Tim , Bradwell Hannah , Connolly Luke J , Algie Kim , Anil Krithika , Halliday Bradley , Houston Sandra , Dennett Rachel , Chatfield Sarah , Buckingham Sarah , Freeman Jennifer
Published: September 2021

UNSTRUCTURED

These are author responses to peer review.
Peer Review of “Technologies to Support Assessment of Movement During Video Consultations: Exploratory Study” (Preprint)
Authors: Sadeghi-Demneh Ebrahim
Published: September 2021

UNSTRUCTURED

This is a peer review report.
Seedling Diversity Considerably Changes Near Localities in Three Salinity Zones of Sundarbans Mangrove Forest, Bangladesh
Authors: Helal Siddiqui ASM , Rahman Md. Masudur , Pitol Md. Najmus Sayadat , Islam Md. Akramul , Hasan Sk Md. Mehedi
Published: September 2021

The status of natural seedlings near localities in the Sundarbans Mangrove Forest was assessed through a stratified random sampling method  to observe seedling composition and diversity, importance value index, family importance value, and species evenness. A total of 63 sample plots of 3,990 m2 area were surveyed in three natural and anthropogenic influenced salinity zones of Sundarbans. A total of 16,166 seedlings of 15 species under 12 families were found. Family Euphorbiaceae showed the highest (59.59%) family relative density and Rhizophoraceae presented the highest (20%) family relative diversity Index (FRDI). The maximum family importance value (FIV) showed by Euphorbiaceae (66.26) and the maximum importance value index (IVI) of species has been observed in Excoecaria agallocha (114.74). Excoecaria agallocha showed the highest relative density (59.6%) and relative abundance (39.87%) where the highest relative frequency (15.27%) was observed by Heritiera fomes. The mean stem density and species diversity index in the whole survey area was 2701 stem ha-1 and 0.0009 correspondingly. The Shannon-Wienner's diversity index was 1.52 where the maximum Shannon-Wienner's diversity index was 2.708. The Simpson's diversity index and Dominance of Simpson index were 0.38 and 0.62 with Simpson's reciprocal index 2.632. The Species evenness index, Menhinick’s, and Margalef's indices were 0.561, 0.118, and 1.445 respectively. The Species diversity index of the three salinity zones were 0.0017, 0.0029, and 0.0035 respectively. The Shannon-Wienner's diversity index of Low Salinity Zone (LSZ), Moderate Salinity Zone (MSZ), and Strong Salinity Zone (SSZ) were 0.887, 1.369, and 1.845 correspondingly where LSZ (0.632) showed the highest Simpson's diversity index follow ed by MSZ (0.394) and SSZ (0.21). The Species evenness index for LSZ, MSZ, and SSZ were 0.346, 0.505, and 0.742 where Menhinick’s Index were 0.148, 0.210, and 0.207 respectively. The analysis showed poor diversity indices and the area was dominated by few species with few families. The status is also reduced with increasing salinity.
La frontera móvil entre constitucionalidad y legalidad en la procedencia del amparo directo en revisión
Authors: Lara Chagoyán Roberto
Published: September 2021

El presente artículo se ocupa de plantear, denunciar y analizar un problema relacionado con la enorme discrecionalidad que se genera a la hora en que la Corte Suprema de nuestro país decide la procedencia de un recurso de revisión en amparo directo. Demostraré que el enunciado “La Suprema Corte, en su papel de tribunal constitucional, sólo debe ocuparse de cuestiones propiamente constitucionales” es manifiestamente falso, porque la propia legislación y la jurisprudencia aplicables permiten que la procedencia de dicho recurso dependa más de la discrecionalidad de los ministros —tolerada por el propio sistema— que de reglas precisas y objetivas. Asimismo, expondré las razones que a mi juicio han provocado esta situación y las consecuencias nocivas que genera, especialmente con relación al principio de igualdad.
Límites a la responsabilidad patrimonial por daño moral
Authors: León Oyosa Oscar Antonio
Published: September 2021

A partir del 14 de junio de 2002 la responsabilidad patrimonial del Estado en México no solamente fue elevada a categoría constitucional, sino que fue introducida con carácter objetivo y directo; esto es, para hacerla valer es necesario demostrar que se ha sufrido daño en la esfera jurídica del cual no se tiene el deber jurídico de soportar, sin necesidad de acreditar previamente el actuar ilícito del servidor público que lo causó, pues bajo esta figura el Estado es directamente responsable de los daños causados por sus agentes. Sin embargo, la redacción del texto constitucional cedió al legislador ordinario la imposición de límites a las indemnizaciones derivadas de la responsabilidad patrimonial, mismas que aquél estableció en la Ley Federal de Responsabilidad Patrimonial del Estado, publicada el 31 de diciembre de 2004 en el Diario Oficial de la Federación. Precisamente, tales límites serán motivo de análisis en el presente, con la finalidad de identificar si son constitucionales, o por el contrario, se apartan del fin buscado por la norma fundamental. De igual manera, se valorará la redacción del texto constitucional con relación a las justificaciones para la imposición de límites respecto del daño moral.
Caso Marielle Franco – Tensão entre o segredo de justiça e a liberdade de imprensa (proposta de distensionamento entre os princípios constitucionais)
Authors: Souza Artur César
Published: September 2021

A morte da vereadora brasileira do PSOL (Partido Solicialista e Liberdade), Marielle Franco, e de seu motorista, Anderson Gomes, ocorrida em 14 de março de 2018, no Rio de Janeiro, Brasil, ganhou repercussão nacional e internacional, em especial pelas dúvidas existentes quanto à legitimidade do procedimento investigatório realizado pela polícia brasileira. Há suspeita de que o assassinato foi encomendado por inimigos políticos à milícia do Rio de Janeiro, gerando graves danos aos direitos humanos e ao sistema democrático brasileiro. A partir deste caso, pretende-se analisar a proibição de divulgação dos elementos probatórios inseridos no inquérito policial em razão do segredo de justiça decretado pelo magistrado brasileiro que conduz o procedimento criminal, ensejando certa tensão entre os princípios da liberdade de imprensa e do devido processo legal. Ao final, resguardando-se a higidez e a eficácia de ambos os princípios, apresenta-se (sub censura) uma possível solução sociojurídica na qual a essência de um dos princípios não seja subjugada pelo outro. Nesse sentido, ao mesmo tempo em que não se apóia qualquer censura prévia aos meios de comunicação, sustenta-se que a divulgação de conteúdo probatório resguardado pelo segredo de justiça (devido processo legal) pode caracterizar a inutilidade da prova. Para tanto, vale-se de uma metodologia indutiva e de uma revisão bibliográfica de direito comparado como forma de se dar sustentação aos fundamentos apresentados para a solução da questão.
La falta de garantía de los derechos sexuales en Colombia: ¿cuestión de ineficacia normativa?
Authors: Alzate Jaramillo Alirio Jesús , Mojica Araque Carlos Alberto
Published: September 2021

De los derechos humanos sexuales se reclama constantemente una protección eficaz por parte del poder estatal para poder así verificar una verdadera legitimación de los contenidos constitucionales y legales que se erigen para este propósito. Este artículo analiza las diferentes prescripciones normativas enunciadas a través de la dogmática constitucional y penal, nacional e internacional, que se encauzan para proteger estos derechos, y en donde las diferentes concepciones sobre aquéllos encuentran sin duda una validez en su construcción a partir del concepto de la dignidad humana. Un análisis crítico de esas normas nos permite constatar en principio lo frágil que resultan el poder y la fuerza del Estado para garantizar estos derechos, cuando desde la misma dialéctica es posible construir también un discurso de ineficacia de aquellas normas. No obstante, aquel calificativo verificado de alguna manera en la praxis parece seguir siendo el resultado de la histórica y poco cambiante conducta irracional de sus destinatarios, lo cual impide consolidar una verdadera barrera frente a la eventual trasgresión. Cuando se supere dicha irracionalidad, será entonces posible constatar lo que teleológicamente anhela el Estado a través del derecho y el poder, que entre otros fines está el respeto por los derechos sexuales ajenos.
La jurisdicción y la institucionalidad en Venezuela: Balance y desafíos
Authors: Casal Jesús María
Published: September 2021

Este artículo analiza el papel que ha desempeñado la Sala Constitucional del Tribunal Supremo de Justicia de Venezuela en el desmantelamiento de la institucionalidad democrática que se ha producido en ese país. Se identifican las bases conceptuales y procesales en que se ha apoyado dicha Sala para apuntalar una dominación autoritaria. El autor aborda la importante misión cumplida por tribunales constitucionales en procesos de transición a la democracia o de redemocratización y, a partir de allí, plantea los principales desafíos que debería asumir una jurisdicción constitucional renovada en su integración y en su concepción funcional con la finalidad de asegurar el pluralismo político y el Estado de Derecho en Venezuela. Se señalan también las prácticas procesales y las interpretaciones que deberían ser abandonadas y las que habría que promover. Finalmente, el autor enuncia algunas herramientas que podrían robustecer la autoridad de tal jurisdicción en una posible transición a la democracia.
El diálogo jurisprudencial entre cortes constitucionales: El caso de México
Authors: Cortez Salinas Josafat
Published: September 2021

¿Por qué las cortes supremas usan el derecho internacional? Este trabajo sugiere que en México se comenzó a utilizar dialogo jurisprudencial porque un nuevo juez con un perfil distinto (José Ramón Cossío) decidió hacerlo de forma gradual mediante su equipo de colaboradores que combinaba gente de carrera judicial y gente con trayectoria en la academia y en el litigio. Adicionalmente se muestra como el ministro capacitó a su personal en cortes y tribuna-les internacionales para que tuvieran cercanía y contacto con el derecho internacional. Estos factores combinados con un ambiente favorable a los derechos humanos propiciaron que la Suprema Corte comenzará a usar diálogo jurisprudencial.
La mediación en la sociedad de República Popular China: Comparativa con el modelo de México en el siglo XXI
Authors: García Vázquez Borja
Published: September 2021

La resolución voluntaria de controversias con la ayuda de un tercero imparcial y sin capacidad para imponer una solución, no constituye un sistema exclusivo de occidente. China es heredera de una tradición milenaria en el uso de la mediación, confirmando la eficiencia de un sistema ajeno a ideologías y destinado a reforzar la necesidad de satisfacción de justicia de los ciudadanos. México en los últimos veinte años se ha adherido al empleo de la mediación, con lo que, por medio de la comparativa de ambos países, se pretende detectar aquellos puntos que podrían ser de interés al objeto de fortalecer el cuerpo normativo mexicano en la materia.