bluuebunny/crossref_metadata_2025 huggingface dataset:
Promises and Failures of the Cooperative Food Retail System in Italy
Authors: Arcidiacono Davide
Published: November 2018

The food market is experiencing a period of deep tensions between farmers, food companies, and retailers across the world. This is particularly true in Italy, a Mediterranean country with a strong agricultural tradition and a great interest in the food market. The largest market weight in terms of food retail in Italy is held by national chains linked to the cooperative movement (Coop and Conad) that has promised to ensure more collaborative and less imbalanced relationships between producers and distributors, along with a stronger connection to the territory and socially responsible corporate management. The Coop is currently the biggest cooperative in Italy. Its increasing power in the Italian food retail system has caused it to behave like an oligopoly that has exploited its proximity to left-wing parties to obtain an advantageous position in some markets (ex: Emilia, Liguria, etc.). Equally alarming is a growing financialization which has led to the bankruptcy of CoopCa and Coop Operaie of Trieste, affecting approximately 20,000 investors. The recent crisis in food retail is redirecting firms’ strategies and producing new forms of food distribution such as Alternative Food Networks that are trying to restore the mission and values of the old consumer cooperatives.
Deepening and Connecting Democratic Processes. The Opportunities and Pitfalls of Mini-Publics in Renewing Democracy
Authors: Michels Ank , Binnema Harmen
Published: November 2018

In recent decades, so-called “mini-publics” have been organized in many countries to renew policy making and democracy. One characteristic of mini-publics is that the selection of the participants is based on random sampling or sortition. This gives each member of the community an equal chance of being selected. Another feature is that deliberation forms the core of the process of how proposals are developed. In this paper, we investigate the possibilities and challenges of sortition and deliberation in the context of the call for a deepening of democracy and more citizen engagement in policy making. Based on extensive research on citizens’ forums (G1000) in The Netherlands, we show the potential of mini-publics, but a number of shortcomings as well. Some of these are related to the specific design of the G1000, while others are of a more fundamental nature and are due to the contradictory democratic values that deliberative mini-publics try to combine. One of these concerns the tension between the quality of deliberation and political impact. We conclude that combining institutional approaches could be a way out to deal with these tensions and a step forward to both deepen and connect democratic processes.
Decreasing Respondent Heterogeneity by Likert Scales Adjustment via Multipoles
Authors: Lipovetsky Stan , Conklin Michael
Published: November 2018

A description of Likert scales can be given using the multipoles technique known in quantum physics and applied to behavioral sciences data. This paper considers decomposition of Likert scales by the multipoles for the application of decreasing the respondents’ heterogeneity. Due to cultural and language differences, different respondents habitually use the lower end, the mid-scale, or the upper end of the Likert scales which can lead to distortion and inconsistency in data across respondents. A big impact of different kinds of respondent is well known, for instance, in international studies, and it is called the problem of high and low raters. Application of a multipoles technique to the row-data smoothing via prediction of individual rates by the histogram of the Likert scale tiers produces better results than standard row-centering in data. A numerical example by marketing research data shows that the results are encouraging: while a standard row-centering produces a poor outcome, the dipole-adjustment noticeably improves the obtained segmentation results.
A Non-Mixture Cure Model for Right-Censored Data with Fréchet Distribution
Authors: Kutal Durga H. , Qian Lianfen
Published: November 2018

This paper considers a non-mixture cure model for right-censored data. It utilizes the maximum likelihood method to estimate model parameters in the non-mixture cure model. The simulation study is based on Fréchet susceptible distribution to evaluate the performance of the method. Compared with Weibull and exponentiated exponential distributions, the non-mixture Fréchet distribution is shown to be the best in modeling a real data on allogeneic marrow HLA-matched donors and ECOG phase III clinical trial e1684 data.
R&D Investments and Firm Value: Evidence from China
Authors: Kim Woo , Park Kunsu , Lee Sang , Kim Hongyoung
Published: November 2018

This study examines whether R&D investments are non-linearly related to firm value. Using a sample of 563 Chinese listed firms between 2005 and 2013, we find that R&D investments have an inverted U-shaped relationship with firm value. This finding indicates that as R&D investments increase, firm value increases to a certain level and then decreases. We further find the presence of an inverted U-shaped relationship in firms with low state ownership. However, we find no evidence of a non-linear relationship in firms with high state ownership. These results suggest that the inverted U-shaped relationship is more pronounced for firms with low state ownership than for firms with high state ownership. Moreover, we find that there is an inverted U-shaped relationship between R&D investments and firm value in firms with high growth opportunities. In contrast, for firms with low growth opportunities, their relationship has a U-shaped pattern. These results are robust to robust standard errors clustered at the firm level, controlling for industry fixed effects, and omitting variable biases. Overall, our empirical evidence extends and complements the literature on the R&D investments–firm value relationship by considering their non-linear pattern. This study provides important implications for stakeholders, such as investors, policy makers, standard-setters, state owners, and regulators. Specifically, our findings can be useful to policy makers who pursue long-term performance objectives.
A Study on the Factors Affecting Consumers’ Willingness to Accept Clothing Rentals
Authors: Tu Jui-Che , Hu Chi-Ling
Published: November 2018

Fashionable clothes resource suppliers are directly linked with resource consumers through the Internet, thus replacing the traditional model. With fashionable clothes as the products for renting, this study helps relevant enterprises understand the factors influencing consumers’ adoption of renting and their attitude and behavioral intention towards clothes renting. Taking the theory of planned behavior as the theoretical foundation, this study thus adopts the technology acceptance model (TAM), the innovation diffusion theory (IDT), the structural equation model (SEM), and the collected information to develop a research methodology that is both theoretical and practical. According to the research results, compatibility matters the most in driving consumers to have a positive assessment and perception of online clothes renting in terms of behavior and attitude. Additionally, personal innovativeness has significant effects and can help relevant enterprises find their target markets. In terms of subjective norm, interpersonal relationship also has a significant influence, showing that consumers today pay much more attention to friends’ information sources. The self-efficacy of the perceived behavioral control also has a noticeable impact. Therefore, relevant enterprises need to consider the operability of online clothes renting to prevent consumers from feeling frustrated in their ability to use it, thus reducing their use intention.
Technology: A Necessary but Not Sufficient Condition for Future Personal Mobility
Authors: Martínez-Díaz Margarita , Soriguera Francesc , Pérez Ignacio
Published: November 2018

Technological advances revolutionize industrial processes, science, communications, and our way of life. However, developed societies have reached a stage in which the fascination with technological innovations often results in their indiscriminate consumption. In this paper, road traffic is used as a line of argument to demonstrate that the random introduction of technology does not imply benefits to society. Particularly, it is analyzed why some of the potential benefits of technological progress are lost in fields such as traffic monitoring, data handling, and traffic management, or in sustainable mobility initiatives, such as the introduction of electric vehicles or the implementation vehicle sharing projects. The risks faced in the future advent of autonomous vehicles are also discussed, and ideas for improvement suggested. A critical reflection on other transportation modes that are expected to be realized in the near future is included as well. The performed analysis evidences that the potential improvement in personal mobility will not become a reality if it exclusively relies on the latest technological devices, in line with consumers’ fantasies or economic interests. This is a statement that could be generalized to many other fields. The implementation/consumption of a particular technology should not be an objective in itself, but a tool to bring benefits to society.
An Evaluation of Local Comprehensive Plans Toward Sustainable Green Infrastructure in US
Authors: Kim Hyun Woo , Tran Tho
Published: November 2018

The benefits of green infrastructure have been verified at the site-level by many empirical studies. However, there is limited understanding of how local governments prepare and implement green infrastructure planning in practice. This study employs the content analysis method to examine the quality of local comprehensive plans regarding sustainable green infrastructure in 60 municipalities of the United States. The study uses regression analysis to explain the variance of plan quality. Study results indicate that key green infrastructure principles were not fully incorporated in the existing sampled plans, with average score of 19.6 out of 50. While plan quality scores were slightly higher in counties than in cities, both areas could significantly improve plan quality with detailed policies, action strategies, and implementation tactics for green infrastructure planning and management. Regression analysis further identified that planning capacities, as well as socio-economic characteristics of study area may impact overall plan quality. The findings of this study demonstrate the importance of incorporating detailed green infrastructure principles whenever local planners adopt or amend regional plans in order to improve plan quality and to support implementation.
A Countermeasure for Preventing Flexibility Deficit under High-Level Penetration of Renewable Energies: A Robust Optimization Approach
Authors: Jeong Jinwoo , Shin Heewon , Song Hwachang , Lee Byongjun
Published: November 2018

An energy paradigm shift has rapidly occurred around the globe. One change has been an increase in the penetration of sustainable energy. However, this can affect the reliability of power systems by increasing variability and uncertainty from the use of renewable resources. To improve the reliability of an energy supply, a power system must have a sufficient amount of flexible resources to prevent a flexibility deficit. This paper proposes a countermeasure for protecting nonnegative flexibility under high-level penetration of renewable energy with robust optimization. The proposed method is divided into three steps: (i) constructing an uncertainty set with the capacity factor of renewable energy, (ii) searching for the initial point of a flexibility deficit, and (iii) calculating the capacity of the energy storage system to avoid such a deficit. In this study, robust optimization is applied to consider the uncertainty of renewable energy, and the results are compared between deterministic and robust approaches. The proposed method is demonstrated on a power system in the Republic of Korea.
Family Female Executives and Firm Financial Performance
Authors: Giraldez-Puig Pilar , Berenguer Emma
Published: November 2018

The aim of this paper is to analyze the relationship of family executive women with firm performance in family firms. We have obtained a final sample of 269 family and non-family firms (comprising 3073 firm/year observations) from the Spanish High Council of Chamber (SHCC) website, while data were collected from System for Analysis of Iberian Balances database (SABI) for the period 2000 to 2011. Applying a generalized method of moments (GMM) panel data methodology, we observe a positive effect on the return on assets (ROA) depending on the existence of family ties of executive women. Several implications for the career development of women in family firms arise from our results.
An Adaptable Engineering Support Framework for Multi-Functional Energy Storage System Applications
Authors: Zanabria Claudia , Andrén Filip Pröstl , Strasser Thomas I.
Published: November 2018

A significant integration of energy storage systems is taking place to offer flexibility to electrical networks and to mitigate side effects of a high penetration of distributed energy resources. To accommodate this, new processes are needed for the design, implementation, and proof-of-concept of emerging storage systems services, such as voltage and frequency regulation, and reduction of energy costs, among others. Nowadays, modern approaches are getting popular to support engineers during the design and development process of such multi-functional energy storage systems. Nevertheless, these approaches still lack flexibility needed to accommodate changing practices and requirements from control engineers and along the development process. With that in mind, this paper shows how a modern development approach for rapid prototyping of multi-functional battery energy storage system applications can be extended to provide this needed flexibility. For this, an expert user is introduced, which has the sole purpose of adapting the existing engineering approach to fulfill any new requirements from the control engineers. To achieve this, the expert user combines concepts from model-driven engineering and ontologies to reach an adaptable engineering support framework. As a result, new engineering requirements, such as new information sources and target platforms, can be automatically included into the engineering approach by the expert user, providing the control engineer with further support during the development process. The usefulness of the proposed solution is shown with a selected use case related to the implementation of an application for a battery energy storage system. It demonstrates how the expert user can fully adapt an existing engineering approach to the control engineer’s needs and thus increase the effectiveness of the whole engineering process.
Influence of Personality Traits on Consumer Preferences: The Case of Office Chair Selection by Attractiveness
Authors: Ko Ya-Chuan , Lo Chi-Hung , Chen Chi-Chuan
Published: November 2018

With increasing living standards, a modern product is required to provide emotional links between a user’s personality and their work environment, in addition to satisfying functional and physiological needs. Since office workers in Taiwan have average daily working hours of over 8 h, they spend lots of time on office chairs, and nowadays more companies are willing to buy good chairs so that their employees can deliver higher efficiency under a more comfortable office environment. After interviewing a group of experts, office chairs are classified into 7 types, and the participants’ personality traits are classified into 4 categories. The influence of different personality traits on the evaluation of office chairs by attractiveness is analyzed by quantification theory type I. Design elements that can better deliver an office chair’s attractiveness are determined. The results allow future designers to improve their designs by identifying the preferences of target users under difference office scenarios.
The Effects on Greenhouse Gas Emissions of Ecological Intensification of Meat Production with Rainfed Sown Biodiverse Pastures
Authors: Morais Tiago G. , Teixeira Ricardo F. M. , Domingos Tiago
Published: November 2018

Feed production is an important contributor to the environmental impacts caused by livestock production. In Portugal, non-dairy cattle are commonly fed with a mixture of grazing and forages/concentrate feed. Sown biodiverse permanent pastures rich in legumes (SBP) were introduced to provide quality animal feed and offset concentrate consumption. SBP also sequester large amounts of carbon in soils. Here, we used a comparative life cycle assessment approach to test the substitution of concentrate through installation of high-yield SBP. Using field data for the Alentejo region in Portugal, we compare the global warming potential of a baseline scenario where cattle is fed in low-yield, semi-natural pastures supplemented with feeds that vary in the ratio of silage to concentrate, and a second scenario where the feed is substituted with high-yield SBP. Although SBP use more fertilizers and machinery, this replacement avoids the emission of about 3 t CO2eq/ha even after SBP stop sequestering carbon. Using crude fiber to establish the equivalence between scenarios leads to higher avoided impact, owing to the fact that the fiber content of SBP is also higher. SBP can avoid 25% emissions from beef production per kg of live animal weight.
The Chinese Socio-Cultural Sustainability Approach: The Impact of Conservation Planning on Local Population and Residential Mobility
Authors: Chen Yue , Yang Jianqiang
Published: November 2018

Retaining indigenous populations is vital to the sustainable development and conservation of historic urban areas. However, little attention has been paid to Chinese conservation planning in an effort to safeguard indigenous people. This paper investigates population change and residential mobility in Chinese historic urban areas by applying demographic analysis and regression models to survey data collected in the Ping-Jiang Historic Quarter. Results indicate that few relocation behaviors are a result of the welfare housing policy and property ownership. However, residents’ intentions to move have increased, due to declining living conditions and tourism development in recent years. Classified by property ownership, public housing tenants and rented housing migrants were more willing to move, while private housing owners preferred to stay. Accordingly, there have been increasing trends of aging, poverty growth and population displacement, epitomized by the public housing population. Assessing planning impacts, welfare policy reduced residential mobility while undermining residents’ self-reliance to maintain their own houses. Without substantial social participation and community support, top-down conservation planning could only slow, rather than reverse, the trend of socio-cultural decline.
Energy Consumption Optimization in Irrigation Networks Supplied by a Standalone Direct Pumping Photovoltaic System
Authors: Pardo Picazo Miguel Ángel , Juárez Juan Manzano , García-Márquez Diego
Published: November 2018

Due to the fact that irrigation networks are water and energy hungry and that both resources are scarce, many strategies have been developed to reduce this consumption. Solar energy sources have emerged as a green alternative with lower energy costs and, consequently, lower environmental impacts. In this work, a new methodology is proposed to select a scheduled program for irrigation which minimizes the number of photovoltaic solar panels to be installed and which better fits energy consumption (calculated for discrete potential combinations, assisted by programming software) to available energy obtained by panels without any power conditioning unit. Thus, the irrigation hours available to satisfy the water demands are limited by sunlight, the schedule type of irrigation has to be rigid (rotation predetermined), and the pressure at any node has to be above the minimum pressure required by standards. A case study was undertaken and, after running the software 105 times, the best result was an irrigation schedule which satisfied all the requirements, involving the installation of 651 solar panels and energy consumption of 428.74 kWh per day, to deliver water to orchards of different varieties of citrus fruit spread over 167.7 ha.
MNEs Subsidiary Training and Development and Firm Innovative Performance: The Moderating Effects of Tacit and Explicit Knowledge Received from Headquarters
Authors: Boadu Francis , Xie Yu , Du Yi-Fei , Dwomo-Fokuo Elizabeth
Published: November 2018

This paper set out to investigate the ways training and development impacts on firm innovative performance as well as the moderating role of knowledge transfer received on training and development and firm innovative performance, using a sample of 229 foreign subsidiaries of multinational enterprises (MNEs) operating in China. We adopt hierarchical linear modeling, and the results of the study reveal that both on-the-job training and development and off-the-job training and development have an influence on the firm innovative performance. Also, the empirical results of the study demonstrate that the moderating effect of tacit and explicit knowledge received on the relationship between both on-the-job training and development and off-the-job training and development and firm innovative performance are stronger. This paper shows that continues updating of skills, ability and knowledge of the workforce through on-the job training and development and off-the job training development programs might boost creativity and innovation of business organizations.
German Winegrowers’ Motives and Barriers to Convert to Organic Farming
Authors: Siepmann Laura , Nicholas Kimberly A.
Published: November 2018

Agriculture plays a crucial role in meeting the Sustainable Development Goals, with organic farming being one important potential contributor to environmental, economic, and social sustainability. Despite a national goal of 20% organic agriculture, currently only 6.2% of Germany’s farmland is organic, and conversion rates are slowing down. However, one bright spot is organic viticulture in Germany, which has four times higher conversion rates, but literature on organic viticulture in Germany is scarce and it is unknown what factors contribute to its relative success. We used the largest wine regions in Germany, Pfalz and Rheinhessen, as a case study to investigate winegrowers’ motives and barriers to convert to organic farming in practice. We compared our interview results with literature from throughout the European Union, analyzing the findings using the five capitals framework to assess livelihood strategies. The results indicate that the motives for organic farming most often identified in the literature and interviews are a pro-organic ideology of the farmer (human capital) and supportive social networks (social capital). Barriers to convert to organic farming were skeptical attitudes toward social networks (social capital) and doubting the environmental benefits of organic winegrowing, especially the use of copper (natural capital). Additional barriers were a farmer’s ideology against organic farming (human capital), identified from the interviews, while the literature discussed financial risks, especially during the conversion periods (financial capital). In the particular case of organic wines in Pfalz and Rheinhessen, it was important to be able to tell a story around wines that stresses wine quality. We conclude that potential avenues to increase organic farming in Germany include addressing the use and environmental impacts of copper, addressing ideological barriers against organic farming, supporting the possibility to tell the story behind a wine, and increased financial support.
Reusing Pruning Residues for Thermal Energy Production: A Mobile App to Match Biomass Availability with the Heating Energy Balance of Agro-Industrial Buildings
Authors: Bisaglia Carlo , Brambilla Massimo , Cutini Maurizio , Bortolotti Antonio , Rota Guido , Minuti Giorgio , Sargiani Roberto
Published: November 2018

Using the pruning residues of woody crops can be beneficial in many ways (e.g., excellent energy balance, a net reduction in pollutant emission and a positive contribution to global warming control). This article describes the background work and development of a new support tool that will allow the user to know the amount and quality of pruning residue required to meet the energy requirements to heat both residential and agro-industrial buildings (e.g., greenhouses). Knowing the average amount of pruned biomass (t d.m. ha−1), the average lower heating value of wood (4.00 kWh kg−1) and the average efficiency of a woody biomass boiler (90%) enabled the overall available net energy yearly amount (kWh year−1) to be determined. This was compared to the overall energy requirements (kWh year−1) of agro-industrial buildings, which are a result of their main features (e.g., maximum heatable surface, building energy classification and the climatic zone). Depending on user needs, the tool suggests the amount of required biomass and, if not entirely available, what amount of fossil fuels are required to fulfill the energy requirement. The algorithm output was compared with the results of two case studies carried out on seven farm buildings and nine greenhouses. Knowing the amount and energy potential of the available biomass allows for planning and evaluation of the planned benefits.
Simulating the Evolution Mechanism of Inner Innovation in Large-Scale Construction Enterprise with an Improved NK Model
Authors: Chen Tao , Huang Guangqiu , Olanipekun Ayokunle Olubunmi
Published: November 2018

The aim of this study is to simulate the self-organized evolution mechanism of inner innovation of large-scale construction enterprises (LSCE) under different contexts. Based on NK stochastic combinatorial optimization model with two parameters (N, K), this study proposes three modules—ambidexterity, punctuated equilibrium, and automation—to simulate the change behaviors of the inner innovation system. Furthermore, this study analyses the influence of factor correlation on inner innovation performance under discusses nine different combination situations. The research results show that (a) regardless of how the relationship strength changes, fitness increases with an increasing K value; and (b) the comparison of optimization modes show that the punctuated equilibrium mode can guarantee the long- and short-term inner innovation performance LSCE. This study therefore reveals the mutual effects of the factors in the inner innovation system in LSCE and provides an effective model for internal systems analyses in the construction industry and in other sectors.
Ephemeral ID Beacon-Based Improved Indoor Positioning System
Authors: Kang Jinsu , Seo Jeonghoon , Won Yoojae
Published: November 2018

Recently, the rapid development of mobile devices and communication technologies has dramatically increased the demand for location-based services that provide users with location-oriented information and services. User location in outdoor spaces is measured with high accuracy using GPS. However, because the indoor reception of GPS signals is not smooth, this solution is not viable in indoor spaces. Many on-going studies are exploring new approaches for indoor location measurement. One popular technique involves using the received signal strength indicator (RSSI) values from the Bluetooth Low Energy (BLE) beacons to measure the distance between a mobile device and the beacons and then determining the position of the user in an indoor space by applying a positioning algorithm such as the trilateration method. However, it remains difficult to obtain accurate data because RSSI values are unstable owing to the influence of elements in the surrounding environment such as weather, humidity, physical barriers, and interference from other signals. In this paper, we propose an indoor location tracking system that improves performance by correcting unstable RSSI signals received from BLE beacons. We apply a filter algorithm based on the average filter and the Kalman filter to reduce the error range of results calculated using the RSSI values.
On Classical Gauss Sums and Some of Their Properties
Authors: Chen Li
Published: November 2018

The goal of this paper is to solve the computational problem of one kind rational polynomials of classical Gauss sums, applying the analytic means and the properties of the character sums. Finally, we will calculate a meaningful recursive formula for it.
A Novel Tool for Supervised Segmentation Using 3D Slicer
Authors: Chalupa Daniel , Mikulka Jan
Published: November 2018

The rather impressive extension library of medical image-processing platform 3D Slicer lacks a wide range of machine-learning toolboxes. The authors have developed such a toolbox that incorporates commonly used machine-learning libraries. The extension uses a simple graphical user interface that allows the user to preprocess data, train a classifier, and use that classifier in common medical image-classification tasks, such as tumor staging or various anatomical segmentations without a deeper knowledge of the inner workings of the classifiers. A series of experiments were carried out to showcase the capabilities of the extension and quantify the symmetry between the physical characteristics of pathological tissues and the parameters of a classifying model. These experiments also include an analysis of the impact of training vector size and feature selection on the sensitivity and specificity of all included classifiers. The results indicate that training vector size can be minimized for all classifiers. Using the data from the Brain Tumor Segmentation Challenge, Random Forest appears to have the widest range of parameters that produce sufficiently accurate segmentations, while optimal Support Vector Machines’ training parameters are concentrated in a narrow feature space.
SS1P Immunotoxin Induces Markers of Immunogenic Cell Death and Enhances the Effect of the CTLA-4 Blockade in AE17M Mouse Mesothelioma Tumors
Authors: Leshem Yasmin , King Emily M. , Mazor Ronit , Reiter Yoram , Pastan Ira
Published: November 2018

SS1P is an anti-mesothelin immunotoxin composed of a targeting antibody fragment genetically fused to a truncated fragment of Pseudomonas exotoxin A. Delayed responses reported in mesothelioma patients receiving SS1P suggest that anti-tumor immunity is induced. The goal of this study is to evaluate if SS1P therapy renders mesothelioma tumors more sensitive to cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) immune checkpoint blockade. We evaluated the ability of SS1P to induce adenosine triphosphate (ATP) secretion and calreticulin expression on the surface of AE17M mouse mesothelioma cells. Both properties are associated with immunogenic cell death. Furthermore, we treated these tumors with intra-tumoral SS1P and systemic CTLA-4. We found that SS1P increased the release of ATP from AE17M cells in a dose and time-dependent manner. In addition, SS1P induced calreticulin expression on the surface of AE17M cells. These results suggest that SS1P promotes immunogenic cell death and could sensitize tumors to anti-CTLA-4 based therapy. In mouse studies, we found that the combination of anti-CTLA-4 with intra-tumoral SS1P induced complete regressions in most mice and provided a statistically significant survival benefit compared to monotherapy. The surviving mice were protected from tumor re-challenge, indicating the development of anti-tumor immunity. These findings support the use of intra-tumoral SS1P in combination with anti-CTLA-4.
Cyanobacterial Blooms and Microcystins in Southern Vietnam
Authors: Trung Bui , Dao Thanh-Son , Faassen Elisabeth , Lürling Miquel
Published: November 2018

Studies on cyanobacteria in Vietnam are limited and mainly restricted to large reservoirs. Cyanobacterial blooms in small water bodies may pose a health risk to local people. We sampled 17 water bodies in the vicinity of urban settlements throughout the Mekong basin and in southeast Vietnam. From these, 40 water samples were taken, 24 cyanobacterial strains were isolated and 129 fish, 68 snail, 7 shrimp, 4 clam, and 4 duck samples were analyzed for microcystins (MCs). MCs were detected up to 11,039 µg/L or to 4033 µg/g DW in water samples. MCs were detected in the viscera of the animals. MC-LR and MC-RR were most frequently detected, while MC-dmLR, MC-LW, and MC-LF were first recorded in Vietnam. Microcystis was the main potential toxin producer and the most common bloom-forming species. A potential health hazard was found in a duck–fish pond located in the catchment of DauTieng reservoir and in the DongNai river where raw water was collected for DongNai waterwork. The whole viscera of fish and snails must be completely removed during food processing. Cyanobacterial monitoring programs should be established to assess and minimize potential public health risks.
Phylogeny and Mycotoxin Characterization of Alternaria Species Isolated from Wheat Grown in Tuscany, Italy
Authors: Ramires Francesca , Masiello Mario , Somma Stefania , Villani Alessandra , Susca Antonia , Logrieco Antonio , Luz Carlos , Meca Giuseppe , Moretti Antonio
Published: November 2018

Wheat, the main source of carbohydrates worldwide, can be attacked by a wide number of phytopathogenic fungi, included Alternaria species. Alternaria species commonly occur on wheat worldwide and produce several mycotoxins such as tenuazonic acid (TA), alternariol (AOH), alternariol-monomethyl ether (AME), and altenuene (ALT), provided of haemato-toxic, genotoxic, and mutagenic activities. The contamination by Alternaria species of wheat kernels, collected in Tuscany, Italy, from 2013 to 2016, was evaluated. Alternaria contamination was detected in 93 out of 100 field samples, with values ranging between 1 and 73% (mean of 18%). Selected strains were genetically characterized by multi-locus gene sequencing approach through combined sequences of allergen alt1a, glyceraldeyde-3-phosphate dehydrogenase, and translation elongation factor 1α genes. Two well defined groups were generated; namely sections Alternaria and Infectoriae. Representative strains were analyzed for mycotoxin production. A different mycotoxin profile between the sections was shown. Of the 54 strains analyzed for mycotoxins, all strains included in Section Alternaria produced AOH and AME, 40 strains (99%) produced TA, and 26 strains (63%) produced ALT. On the other hand, only a very low capability to produce both AOH and AME was recorded among the Section Infectoriae strains. These data show that a potential mycotoxin risk related to the consumption of Alternaria contaminated wheat is high.
Bioinformatics and Functional Assessment of Toxin-Antitoxin Systems in Staphylococcus aureus
Authors: Habib Gul , Zhu Qing , Sun Baolin
Published: November 2018

Staphylococcus aureus is a nosocomial pathogen that can cause chronic to persistent infections. Among different mediators of pathogenesis, toxin-antitoxin (TA) systems are emerging as the most prominent. These systems are frequently studied in Escherichia coli and Mycobacterial species but rarely explored in S. aureus. In the present study, we thoroughly analyzed the S. aureus genome and screened all possible TA systems using the Rasta bacteria and toxin-antitoxin database. We further searched E. coli and Mycobacterial TA homologs and selected 67 TA loci as putative TA systems in S. aureus. The host inhibition of growth (HigBA) TA family was predominantly detected in S. aureus. In addition, we detected seven pathogenicity islands in the S. aureus genome that are enriched with virulence genes and contain 26 out of 67 TA systems. We ectopically expressed multiple TA genes in E. coli and S. aureus that exhibited bacteriostatic and bactericidal effects on cell growth. The type I Fst toxin created holes in the cell wall while the TxpA toxin reduced cell size and induced cell wall septation. Besides, we identified a new TA system whose antitoxin functions as a transcriptional autoregulator while the toxin functions as an inhibitor of autoregulation. Altogether, this study provides a plethora of new as well as previously known TA systems that will revitalize the research on S. aureus TA systems.
Recent Advances in Zika Virus Vaccines
Authors: Garg Himanshu , Mehmetoglu-Gurbuz Tugba , Joshi Anjali
Published: November 2018

The recent outbreaks of Zika virus (ZIKV) infections and associated microcephaly in newborns has resulted in an unprecedented effort by researchers to target this virus. Significant advances have been made in developing vaccine candidates, treatment strategies and diagnostic assays in a relatively short period of time. Being a preventable disease, the first line of defense against ZIKV would be to vaccinate the highly susceptible target population, especially pregnant women. Along those lines, several vaccine candidates including purified inactivated virus (PIV), live attenuated virus (LAV), virus like particles (VLP), DNA, modified RNA, viral vectors and subunit vaccines have been in the pipeline with several advancing to clinical trials. As the primary objective of Zika vaccination is the prevention of vertical transmission of the virus to the unborn fetus, the safety and efficacy requirements for this vaccine remain unique when compared to other diseases. This review will discuss these recent advances in the field of Zika vaccine development.
Sharp Interface Approach for Regional and Well Scale Modeling of Small Island Freshwater Lens: Tongatapu Island
Authors: Babu Roshina , Park Namsik , Yoon Sunkwon , Kula Taaniela
Published: November 2018

Sustainable management of small island freshwater resources requires an understanding of the extent of freshwater lens and local effects of pumping. In this study, a methodology based on a sharp interface approach is developed for regional and well scale modeling of island freshwater lens. A quasi-three-dimensional finite element model is calibrated with freshwater thickness where the interface is matched to the lower limit of the freshwater lens. Tongatapu Island serves as a case study where saltwater intrusion and well salinization for the current state and six long-term stress scenarios of reduced recharge and increased groundwater pumping are predicted. Though no wells are salinized currently, more than 50% of public wells are salinized for 40% decreased recharge or increased groundwater pumping at 8% of average annual recharge. Risk of salinization for each well depends on the distance from the center of the well field and distance from the lagoon. Saltwater intrusions could occur at less than 50% of the previous estimates of sustainable groundwater pumping where local pumping was not considered. This study demonstrates the application of a sharp interface groundwater model for real-world small islands when dispersion models are challenging to be implemented due to insufficient data or computational resources.
Multi-Crop Production Decisions and Economic Irrigation Water Use Efficiency: The Effects of Water Costs, Pressure Irrigation Adoption, and Climatic Determinants
Authors: Fan Yubing , Massey Raymond , Park Seong C.
Published: November 2018

In an irrigated multi-crop production system, farmers make decisions on the land allocated to each crop, and the subsequent irrigation water application, which determines the crop yield and irrigation water use efficiency. This study analyzes the effects of the multiple factors on farmers’ decision making and economic irrigation water use efficiency (EIWUE) using a national dataset from the USDA Farm and Ranch Irrigation Survey. To better deal with the farm-level data embedded in each state of the U.S., multilevel models are employed, which permit the incorporation of state-level variables in addition to the farm-level factors. The results show higher costs of surface water are not effective in reducing water use, while groundwater costs show a positive association with water use on both corn and soybean farms. The adoption of pressure irrigation systems reduces the soybean water use and increases the soybean yield. A higher EIWUE can be achieved with the adoption of enhanced irrigation systems on both corn and soybean farms. A high temperature promotes more the efficient water use and higher yield, and a high precipitation is associated with lower water application and higher crop yield. Intraclass correlation coefficients (ICC) suggest a moderate variability in water application and EIWUE is accounted by the state-level factors with ICC values greater than 0.10.
Long-Term GIS Analysis of Seaside Impacts Associated to Infrastructures and Urbanization and Spatial Correlation with Coastal Vulnerability in a Mediterranean Area
Authors: Garcia-Ayllon Salvador
Published: November 2018

The relationship between the impacts of coastal perimeter transformations derived from human activity and coastal vulnerability is not easy to assess. The impacts associated with coastal dynamics are phenomena that usually develop very extensively over a considerable time. These are transformations that cause significant environmental damage in vulnerable coastal areas, but whose results are very often not really visible until 10, 20, or even 40 years have elapsed. In addition, the analysis and quantification of the current context in complex territories is particularly difficult, since the spatial feedback of various issues and its consequences can generate an uncertain scenario with many interrelated variables. In this field, the use of GIS tools can be of great help to objectively analyze the relationship between coastal anthropization and its impact on its vulnerability in order to correct wrong inertias in vulnerable coastal areas. To this end, a long-term GIS analysis has been carried out of the impacts from urbanization and seaside infrastructures suffered by a complex Mediterranean coastal area in Spain. This territory, with singular elements such as dune ridges, beaches located in protected areas, and a coastal lagoon, will be evaluated using GIS spatio-temporal indicators over the last 90 years and geostatistical correlation methods. This approach will allow us to better understand the relationship between territorial transformations on the coast and the current coastal vulnerability of this area.
Supporting Sustainable Water Management: Insights from Australia’s Reform Journey and Future Directions for the Murray–Darling Basin
Authors: Papas Maureen
Published: November 2018

Effective regulation of freshwater remains one of the biggest challenges facing our societies. In times of record-breaking weather extremes spurred by a changing climate, decision makers are increasingly aware of the need to formulate more effective governance to ensure the reliability, accessibility, and quality of this life-giving resource. In recent years, the Australian government has played a key role in water management. The government has managed a significant amount of water entitlements in the Murray–Darling Basin (MDB), through its Commonwealth Environmental Water Holder (CEWH) agency, in a bid to increase river flows and thus improve the river system’s environmental and ecological conditions. The CEWH is unique in many respects, and the Australian government’s control of its budget and actions is a critical aspect of the Basin’s sustainable long-term management. Despite the importance of this instrument, this article points out that there are serious issues with the current governance arrangements, such as inherent conflicts in the Murray–Darling Basin Authority’s (MDBA) role, which is a concern raised by the Productivity Commission. This article goes on to recommend the policy changes required to address Basin-wide issues and promote sustainable practices to ensure the MDB’s long-term resilience.
Sustainable Water Management in Iraq (Kurdistan) as a Challenge for Governmental Responsibility
Authors: Yousuf Mahmood A. , Rapantova Nada , Younis Jalal H.
Published: November 2018

During the last few decades, a critical scarcity of water has occurred in the Middle East due to climate change and the mismanagement of water resources. The situation is complicated by the absence of an effective legislative framework at the local level as well as by the incapability and disrepute of the local water authorities. Most Iraqi citizens depend on the surface waters of the Tigris and Euphrates rivers, which have their sources in upstream neighbouring countries. Water crises concerning the shared waters urgently require a solution at the international level. Unfortunately, Iraq has faced several wars in a row (1980–2003), which has prevented the country from establishing its institutions. The rapid increase in the population of the transboundary countries on the Tigris and Euphrates rivers, and the high demands on agriculture, are accelerating water exploitation. In this paper, the present state of water management in Iraq from the viewpoint of the legislative framework, water balance, and transboundary issues will be discussed, with special attention to Kurdistan. Many legislative documents have been established or amended by the Iraqi and Kurdistan parliaments since 2003. In 2015, the Kurdistan Government Ministry of Agriculture and Water Resources, in cooperation with the EU, issued a guide for environmental legislation related to all environmental components such as air, water, and soil. The recommendations on actions needed in the water management in Kurdistan will be presented; they are inspired by the Water Framework Directive (WFD) (2000/60/EC) implemented in EU member states.
Towards Ecological-Economic Integrity in the Jing-Jin-Ji Regional Development in China
Authors: Li Suxiao , Yang Hong , Liu Junguo , Lei Guangchun
Published: November 2018

In China, the regional development policy has been shifting from solely economic orientation to ecologically sound economic growth. Using the Beijing-Tianjin-Hebei (Jing-Jin-Ji) region as a case study, we evaluated the temporal variations in ecosystem service values (ESVs) associated with land use changes from 1990 to 2015. We analyzed the dynamic relations between ESVs and the economy (indicated by the gross domestic product, GDP) by introducing the elasticity indicator (EI), which reflects the growth synchronism between the two, and the ecosystem service load (ESL), which reflects the ecological efficiency of economic growth. The results showed that the land use changes in Jing-Jin-Ji have been characterized by decreases in water areas, cropland, and grassland and increases in woodland and built-up areas. The ESVs of woodland and water areas contributed to 80% of the total ESV of the region, and the total ESV increased by 13.87% as a result of an area increase in woodland (26.87%). The average EI of Jing-Jin-Ji improved from 0.028 to 0.293 over the study period, indicating that the growth of ESVs was being balanced with the growth in the GDP. The average ESL decreased by 1.24, suggesting a significant improvement in ecological efficiency per unit GDP. Within the Jing-Jin-Ji region, large disparities in EI and ESL were shown to exist among Beijing, Tianjin, and Hebei owing to their differences in ecological resources, GDP compositions, and development levels. The study highlights the needs to reinforce woodland and water conservation, adjust economic structures, and balance the intraregional development to achieve the ecological-economic integrity of the region.