bluuebunny/crossref_metadata_2025 huggingface dataset:
The organization of subglacial drainage during the demise of the Finnish Lake District Ice Lobe
Authors: Hepburn Adam J. , Dow Christine F. , Ojala Antti , Mäkinen Joni , Ahokangas Elina , Hovikoski Jussi , Palmu Jukka-Pekka , Kajuutti Kari
Published: October 2024

Abstract. Unknown basal characteristics limit our ability to simulate the subglacial hydrology of rapidly melting contemporary ice sheets. Sediment-based landforms generated beneath Late Pleistocene ice sheets, together with detailed digital elevation models, offer a valuable means of testing basal hydrology models, which describe the flow and dynamics of water in the subglacial system. However, to date no work has evaluated how well process-based subglacial hydrology models represent the hypothesized conditions associated with glaciofluvial landform formation in the palaeo setting. Previous work comparing model output to geomorphological evidence has typically done so using models that do not resolve subglacial processes and instead express likely subglacial water pathways. Here, we explore the ability of the Glacier Drainage System model (GlaDS), a process-based subglacial hydrology model, to represent the genesis conditions associated with a specific glaciofluvial landform termed “murtoos”. Distinctive triangular landforms found throughout Finland and Sweden, murtoos are hypothesized to form 40–60 km from the former Fennoscandian Ice Sheet margin within a “semi-distributed” system at the onset of channelized drainage in small cavities where water pressure is equal to or exceeds ice overburden pressure. Concentrating within a specific ice lobe of the former Fennoscandian Ice Sheet and using digital elevation models with a simulated former ice surface geometry, we forced GlaDS with transient surface melt and explored the sensitivity of our model outcomes to parameter decisions such as the system conductivity and bed topography. Our model outputs closely match the general spacing, direction, and complexity of eskers and mapped assemblages of features related to subglacial drainage in “meltwater routes”. Many of the predictions for murtoo formation are produced by the model, including the location of water pressure equal to ice overburden, the onset of channelized drainage, the transition in drainage modes, and importantly the seasonal sequence of drainage conditions inferred from murtoo sedimentology. These conclusions are largely robust to a range of parameter decisions, and we explore seasonal and inter-annual drainage behaviour associated with murtoo zones and meltwater pathways. Our results demonstrate that examining palaeo basal topography alongside subglacial hydrology model outputs holds promise for the mutually beneficial analyses of palaeo and contemporary ice sheets to assess the controls of hydrology on ice dynamics and subglacial landform evolution.
Virtual Lifelines: Filipino Psychologists' Experiences with Tele-Counseling for Suicide Prevention
Authors: Pangngay Jose J.
Published: October 2024

The COVID-19 pandemic forced a rapid shift to tele-counseling, presenting unique challenges for psychologists, especially those working with high-risk clients. This exploratory multiple-case study investigated the experiences of three Filipino psychologists providing tele-counseling for suicide prevention. The study revealed initial struggles with technology, ethical concerns, and perceived clinical effectiveness. However, the psychologists demonstrated resilience through a two-phase continuous professional development process: orientation and recalibration. Key outcomes included increased clinician enthusiasm, new professional opportunities, and improved ethical responses to crises. Tele-counseling emerged as a client-responsive tool that expands access to mental health services. Despite challenges, tele-counseling can be effective for suicide prevention with proper adaptation and training. These findings underscore the importance of integrating tele-counseling competencies into professional training curricula and developing evidence-based practices for remote crisis intervention.
Precauções padrão e enfermagem: revisão bibliométrica
Authors: Rosa de Sousa Neto Antonio , Beatriz Oliveira de Abreu Karen , Vaz Pierot Esteffany , Marques Rêgo Neta Marly , Viviane de Oliveira Sena Inara , Nunes Almeida Rosângela , Insabralde de Queiroz-Cardoso Andréia , Reis Joaquim de Freitas Daniela
Published: October 2024

Objetivo: Realizar uma revisão bibliométrica sobre as precauções padrão em enfermagem. Método: Este é um estudo bibliométrico com abordagem quantitativa. O pacote R “Bibliometrix” e sua interface web Biblioshiny foram utilizados para revisão. Resultados: Um total de 50 artigos foram selecionados. A maioria dos artigos foi publicada em 2023, distribuídos entre 35 revistas científicas, 170 autores de 86 instituições distintas e 22 países. Os artigos analisados foram citados um total de 553 vezes. Além disso, a análise da estrutura conceitual revelou a existência de dois conjuntos distintos, cada um representando diferentes temas de pesquisa relacionadas às precauções padrão e enfermagem. Conclusão: Pesquisas futuras devem priorizar a investigação dos fatores que afetam a conformidade com as precauções padrão e enfermagem. Isso requer o desenvolvimento de instrumentos robustos e validados para coleta de dados e para a realização de intervenções educativas eficazes, juntamente com a implementação e avaliação dessas intervenções.
Impact of Taxation and Political Stability on Economic Growth of Pakistan
Authors: Malik Abida , Meraj Muhammad
Published: October 2024

This study investigates the impact of taxation and political stability on economic growth in Pakistan. Analyzing GDP data from 1979 to 2019, measured in US dollars and converted to PKR, we assessed political stability using the Polity IV index and included both direct and indirect taxes in our examination. We formulated two hypotheses: one addressing the impact of political stability on GDP and the other examining the influence of taxation on GDP. A range of methodologies, including unit root tests, ARDL (AutoRegressive Distributed Lag) modeling, and error correction models, was employed to analyze both short-term and long-term effects. Our findings indicate a significant positive relationship between economic growth and both taxation and political stability. Effective direct and indirect taxation policies contribute meaningfully to GDP growth, while a stable political environment is crucial for economic development. To enhance these effects, policymakers should focus on developing progressive taxation strategies and ensuring political stability. This study provides essential insights for policymakers, economists, and government officials to improve tax collection practices and foster an environment conducive to sustainable economic growth.
Viral Hepatitis in Lebanon: Prevalence, Challenges, and Future Directions.
Authors:   Lebanese university, faculty of medical sciences. Hadath, Lebanon, Antoine Abou Rached , Joyce Sanyour ,   Lebanese university, faculty of medical sciences. Hadath, Lebanon, Mariam Naboulsy ,   Lebanese university, faculty of medical sciences. Hadath, Lebanon, Cesar Yaghi ,   Saint Joseph university, faculty of medical sciences. Beirut, Lebanon, Ala Sharara ,   American university of Beirut, Faculty of medical science, Beirut, Lebanon
Published: October 2024

Viral hepatitis remains a significant global health challenge, affecting millions of individuals worldwide. In Lebanon, understanding the prevalence and impact of viral hepatitis is crucial, given its implications not only for the health and wellbeing of the Lebanese population but also for regional and global health security. The epidemiology of viral hepatitis in Lebanon has evolved over time, influenced by various socioeconomic and political factors.
Pengaruh Sistem Informasi Akuntansi Terhadap Pengendalian Internal Pada Karyawan Indolampung Tulang Bawang
Authors: Nisa Thoyibatun
Published: October 2024

Penelitian ini bertujuan untuk mengetahui seberapa besar pengaruh Sistem Informasi Akuntansi terhadap pengendalian internal pada karyawan Indolampung Tulang bawang. Sampel penelitian dalam penelitian ini berjumlah 30 karyawan Koperasi Karyawan Indolampung Tulang Bawang. Analisis data yang digunakan dalam penelitian ini menggunakan analisis uji statistik deskriptif, uji validitas instrumen, uji reliabilitas instrumen, uji asumsi klasik, analisis regresi sederhana, uji t (persial), dan koefesien determinan (R2). Hasil penelitian ini menunjukkan bahwa Sistem informasi Akuntansi berpengaruh positif terhadap Pengendalian Internal, hasil tersebut dibuktikan dengan pengujian secara persial menunjukkan bahwa thitung e” ttabel yakni 10,518e” 1,701 dengan nilai signifikansi sebesar 0,000d”0,05 yang artinya variabel Sistem Informasi Akuntansi (X) berpengaruh positif terhadap Pengendalian Internal (Y) di Koperasi Karyawan Indolampung Tulang Bawang. Serta kontribusi variabel Sistem Informasi Akuntansi terhadap Pengendalian Intenal sebesar 79,8% dan sisanya (20,2%) dari variabel lain.
Analisis Perputaran Modal Kerjaterhadap Profitabilitas Pada PT. UNI-CHARM INDONESIA TBK
Authors: Salim Salim
Published: October 2024

PT Uni-Charm Indonesia Tbk. Perusahaan ini menghasilkan tiga lini bisnis, yaitu Baby Care, Feminine Care, serta Health Care. Kegiatan usaha utamanya ialah memproduksi produk-produk higienis seperti tisu basah, pembalut wanita, popok bayi, dan popok dewasa. Permasalahan yang diangkat dalam penelitian ini adalah bagaimana analisis perputaran modal kerja terhadap profitabilitas pada PT Uni- Charm Indonesia Tbk. Penelitian ini bertujuan untuk mengetahui perputaran modal kerja terhadap profitabilitas. Metode yang digunakan dalam penelitian adalah metode deskriptif kuantitatif, dengan data sekunder yaitu dokumen laporan keuangan perusahaan tahun 2019-2020. Selanjutnya menggunakan perhitungan perputaran modal kerja dan rasio profitabilitas Net Profit Margin. Pada perhitungan perputaran modal kerja pada tahun 2019 memperoleh sebanyak 2,62 kali, pada 2020 mengalami peningkatan sebanyak 4,28 kali, dan pada tahun 2021 mengalami penurunan sebanyak 3,75 kali. Hal ini mengindikasikan bahwa perusahaan kurang efektif dalam mengelola modal kerjanya. Pada profitabilitas Net Profit Margin memperoleh pada tahun 2019 sebesar 4,7%, mengalami penurunan pada tahun 2020 sebesar 3,7%, dan pada tahun 2021 mengalami peningkatan sebesar 5,2%. Sehingga dalam penelitian ini menunjukan bahwa perputaran modal kerja berpengaruh terhadap profitabilitas pada PT. Uni-Charm Indonesia Tbk.
Analisis Perhitungan Biaya Pokok Produksi dengan Menggunakan Metode Variable Costing dan Cost Plus Pricing untuk Menentukan Harga Jual Pada Perusahaan Haikal Furniture
Authors: Yuliana Yuliana
Published: October 2024

Haikal furniture bergerak di bidang penjualan pembuatan sofa, service dan custome sofa yang sesuai dengan keinginan pelanggan, perusahaan ini berada di desa bumisari, natar, lampung selatan . permasalahan yang di alami perusahaan ini adalah sejak berdirinya perusahaan pemilik usaha tidak memperhitungkan biaya proses produksi sofa secara terperinci sehingga ada kemungkinan biaya-biaya lain yang tidak terhitung dalam proses produksinya, sehingga penentuan harga jual nya bisa terlalu tinggi atau terlalu rendah. Metode yang di gunakan dalam penelitian ini yaitu variable costing untuk menentukan harga pokok produksi dan cost plus pricing yaitu untuk memperhitungkan harga jual nya. Tujuan penelitian ini yaitu untuk menghitung biaya- biaya yang di gunakan dalam proses pembuatan sofa di perusahaan haikal furniture, hasil yang di dapatkan dalam penelitian ini yaitu mendapatkan besaran harga pokok produksi dan besaran harga jual produk yang lebih tepat dan mampu bersaing dengan harga jual produk yang serupa.
Sistem Pengendalian Intern Terhadap Piutang Pada PT. Mulia Putra Pertama
Authors: Wicaksono Dwi Anggoro Pulung
Published: October 2024

Penelitian ini bertujuan untuk mengetahui apakah pengendalian pengendalian pada PT. Mulia Putra Pertama sudah efektif. Jenis penelitian yang digunakan peneliti yaitu penelitian deskriptif kualitatif. Sumber data yang digunakan yaitu data primer dan data sekunder berupa data, wawancara dan dokumentasi terkait piutang. Teknik analisis data pada penelitian ini yaitu dengan mendeskripsikan faktor-faktor yang terdapat dalam SOP dan COSO. Hasil dari penelitian ini adalah sistem pengendalian intern terhadap piutang pada PT. Mulia Putra Pertama kini sudah efektif dari sisi prosedur, namun dari sisi penerimaan masih kurang maksimal. Kinerja telah sesuai dengan SOP dan juga memperhatikan lima konsep pengendalian internal, yaitu lingkungan pengendalian, risiko, kegiatan, informasi dan komunikasi, serta kegiatan-kegiatan yang membuat kegiatan PT. Mulia Putra Pertama bersifat likuid di proyek non-JO, dan untuk proyek JO harus dapat diperbaiki dalam proses penerimaannya.
Features of Vascularization of the Transitional Zone of the Uterus in Patients with Chronic Nonspecific Endometritis
Authors: Pomortsev A. V. , Kuzmenko E. A. , Kuzmenko N. N. , Dyachenko Yu. Yu. , Avakyan S. M.
Published: October 2024

Aim. Тo study the peculiarities of blood supply to the transitional zone of the uterus in patients with chronic nonspecific endometritis (ChE).

Materials and methods. 106 women aged 22–45 years were examined. The main group included 72 patients with morphologically verified chronic endometritis. We distinguished subgroup I (n = 39.37%) of HE with an autoimmune component, subgroup II (n = 33.31%) with HE without an autoimmune component, as well as a control group consisting of 34 patients with a normal result of morphological examination. Transabdominal and transvaginal ultrasound examination (ultrasound) of the uterus and appendages was performed on the 18th–23rd day of the cycle, with the calculation of the parameter proposed by US — the coefficient of vascularization of the transitional zone of the uterus (k).

Outcomes. In the control group, the average k value was 32 ± 2.6%, in the subgroup of patients with an autoimmune component (subgroup I) — 17.0 ± 4.0%, in the subgroup with a nonimmune component (subgroup II) — 23.0 ± 3.4%.

Statistically significant differences in the k value were obtained between subgroup I and all the others, but there were no differences between subgroup II and the control group.

Autoimmune nonspecific HE was predicted when the vascularization coefficient was below 20.9%. In nonimmune nonspecific HE, the resulting model was not statistically significant. Nonimmune nonspecific HE was predicted when the vascularization coefficient was equal to or higher than 18.6%.

Under normal conditions, the resulting model was statistically significant. The norm was predicted when the vascularization coefficient was equal to or higher than 27.6%.

Conclusion. The proposed coefficient of vascularization of the transitional zone of the uterus (k) showed high diagnostic value in patients with nonspecific СhE and it can be recommended for inclusion in the ultrasound examination protocol at the stage of pre-gravidar preparation.
Features of Magnetic Resonance Diagnostics of Tenosynovial Giant Cell Tumor (Pigmented Villonodular Synovitis)
Authors: Potemkina T. V. , Konopleva Yu. Yu. , Petrova E. B.
Published: October 2024

Aim. Demonstrate the features of magnetic resonance diagnostics of tenosynovial giant cell tumor.

Materials and Methods. Using magnetic resonance imaging, we identified patients with tenosynovial giant cell tumor of the knee joint, describing the diagnostic features and clinical course of diffuse and local forms of the tumor.

Results. Specific MRI patterns of tenosynovial giant cell tumor are hemosiderin deposits, villous and nodular growths of the synovium of the knee joint, joint effusion and bone erosion.

Conclusion. Тenosynovial giant cell tumor is a rare mesenchymal neoplasm arising from the synovium of joints and tendon sheaths, disabling young able-bodied people. Magnetic resonance imaging, being the “gold” standard for radiological diagnostics, helps to identify specific patterns.
Tamoxifen Retinopathy. An Uncommon but Serious Complication: Case Report
Authors: Pierre Lucas  Linhares , Pierre Lara Linhares , Pierre-Filho Paulo de Tarso Ponte
Published: October 2024

Tamoxifen is a selective estrogen receptor modulator most widely used in the treatment of hormone-dependent breast cancer. We describe a case of a 51-year-old woman treated with tamoxifen for 4 years who had gradual diminution of vision in both eyes of three months duration. On examination, visual acuity was 20/40 in the right eye and 20/50 in the left eye. A fundus examination revealed bilateral symmetric crystalline deposits in the macula. There were characteristic structural changes on spectral domain-optical coherence tomography, including abnormalities of the ellipsoid zone and outer nuclear layer.  Subsequently, tamoxifen was switched to anastrozole. Despite cessation of tamoxifen, her vision did not improve. The clinical presentation of tamoxifen retinopathy is discussed, along with the importance of regular ophthalmic examination for individuals receiving tamoxifen, even in low doses.
Perfiles filosóficos. Hombre, sociedad y derecho en el pensamiento contemporáneo
Authors: Serra Juan Pablo
Published: October 2024

José María Carabante, Perfiles filosóficos. Hombre, sociedad y derecho en el pensamiento contemporáneo, Pamplona, Aranzadi, 2022, 128 pp.
Edukasi Proses Publikasi Artikel Ilmiah pada Jurnal Internasional Bereputasi
Authors: Dewi Christine
Published: October 2024

Conducting research and publishing the results of the research and its analysis is one of the main criteria that must be fulfilled by lecturers in order to fulfill the responsibilities of lecturers as part of the Tridharma of Higher Education. The relevance of lecturers conducting investigations, research, and publishing scientific articles is raised substantially by the demands for publication by the higher education community. According to the Regulation of the Minister of Administrative Reform and Bureaucratic Reform (PAN RB) Number 17 of 2013 and the Regulation of the Minister of Education and Culture Number 92 of 2014 issued by the Minister of Education and Culture, academic promotion is recognized for publication in nationally accredited scientific journals as well as international reputable journals in their respective fields. This rule provides direction so that scientific publications and functional positions of lecturers in Indonesia continue to increase. The skills to write and publish scientific articles are very important for researchers, lecturers, and students in Indonesia. However, most of them still have difficulty writing down their findings in the form of scientific publications and publishing them in well-known international journals. Therefore, this activity which is part of community service is carried out to cultivate the ability to write and publish scientific publications for the benefit of students, lecturers and researchers in Indonesia. The Zoom Meeting digital platform is used for service-related operations. Researchers, lecturers, and students from various regions in Indonesia participated in this activity. The information obtained by the participants about the field of scientific writing in well-known international journals is very much.
Keywords : Publication of scientific articles, Writing of scientific articles, Training of reputable journal publications.
Peran Media Video Animasi Stunting Terhadap Pemahaman Stunting Tim Pendamping Keluarga (TPK) di Kecamatan Way Ratai, Pesawaran, Lampung
Authors: Martini Cita , Kartika Tina , Zainal Anna Gustina
Published: October 2024

Stunting menjadi perhatian utama pemerintah karena dampaknya yang signifikan terhadap kualitas sumber daya manusia. Stunting adalah gangguan pertumbuhan anak yang disebabkan oleh kekurangan gizi kronis dan infeksi berulang, yang mengakibatkan tinggi badan anak di bawah standar Kementerian Kesehatan. Menurut UNICEF, stunting dapat menyebabkan masalah jangka panjang, seperti penurunan kemampuan kognitif dan peningkatan risiko penyakit degeneratif. Di Kecamatan Way Ratai, Pesawaran, Lampung, Tim Pendamping Keluarga (TPK) berperan penting dalam mengatasi stunting dengan memberikan edukasi dan pemantauan kepada keluarga berisiko. Namun, pemahaman TPK tentang stunting masih terbatas, yang menghambat efektivitas mereka. Untuk mengatasi masalah ini, penyuluh KB dari BKKBN melakukan pengabdian kepada masyarakat (PKM) pada 22 November 2023, melibatkan 22 anggota TPK yang terdiri dari kader PKK dan kader KB. Penyuluhan menggunakan media video animasi untuk meningkatkan pengetahuan TPK. Penelitian ini menggunakan pendekatan kualitatif fenomenologi untuk meneliti peran video animasi dalam meningkatkan pemahaman TPK, dengan pengumpulan data melalui kuesioner pretest dan posttest serta wawancara. Hasil evaluasi menunjukkan peningkatan pengetahuan peserta sebesar 26,45%. Sebanyak 27,3% anggota TPK merasa video animasi sangat membantu, sementara 72,7% merasa bermanfaat. Peserta menghargai format media yang menarik dan mudah diakses. Mereka menginginkan sesi mendatang yang lebih bervariasi dan menyarankan tambahan materi, seperti leaflet, untuk memperkaya pengalaman belajar mereka. Ini menunjukkan pentingnya mempersiapkan TPK sebagai mitra dalam mengatasi masalah stunting di komunitas mereka.

Kata kunci : animasi, penyuluhan, stunting,
Anti-Cancer Potential of Salaciaoblonga Wall Compounds by Targeting 5HZN and 1Q1A Receptor: A Comprehensive Molecular Docking and Simulation Approaches
Authors: S. Tarihalkar Suraj , Patil Vipul , Kumar Patil Sachin
Published: October 2024

Plants produce phytochemicals with pharmacological properties that have been demonstrated in various conditions. In-silico techniques like molecular docking and virtual screening are being used to clarify the pharmacological aspects of bioactive chemicals of botanical origin. Aromatherapy has focused on plant secondary metabolites' anti-inflammatory, antioxidant, and anticancer capabilities. Essential oils contain monoterpenes and sesquiterpenes, which have several pharmacological activities. Salaciaoblongais a perennial plant with a long tradition of use in Ayurvedic medicine. It contains polyphenols, triterpenes of the friedelane and norfriedelane kinds, sesquiterpenes of the eudesmane type, and glycosides. The extract has positive pharmacological effects due to its interactions with molecular targets inside the human body. The primary goals of the current investigation were to investigate the bioactive compounds and isolates of Salaciaoblonga Wall extract with the receptors 5HZN (BRCA 3) and 1Q1A (IR). Bioactive compounds included 2,4- dimethylamphetamine, 19-hydroxyferruginol, Cyclotrisiloxane, Dulcitol, Epicatechin, Galactinol, Hexadecanoic acid, Kotalagenin-16-acetate, Kotalanol, Lambertic acid, Mangiferin, Neokotalanol, Neosalacinol, Quercetin, Raffinose, Salaciaoblonga Wall, Salasone A, Salasol B, Salasone C, Salasone D, Salasone E, Stachyose, and Trichloroacetic acid. Autodock 4.2.6 was used to dock these compounds to a chosen protein. Molecular docking data was used to identify the optimal binding conformation of inhibitors to enzymes, and protein-ligand complexation provided information on interactions. Salaciaoblonga had the best docking positions and free energy scores, but some had substandard ADME characteristics. This study paves the way for the development of novel medications against cancer-associated molecular targets.
Artificial Intelligence: Future Aspects in the Pharmaceutical Industry an Overview
Authors: Bairagi Aakash , K. Singhai Akhlesh , Jain Ashish
Published: October 2024

Artificial intelligence (AI) has emerged as a potent tool leveraging human-like knowledge to offer swift solutions to intricate challenges. Striking advancements in AI technology and machine learning present a revolutionary opportunity in pharmaceutical drug discovery, formulation, and dosage form testing. By employing AI algorithms that scrutinize vast biological datasets encompassing genomics and proteomics, scientists can pinpoint disease-related targets and forecast their interactions with potential drug candidates. This facilitates a more precise and efficient approach to drug discovery, thereby elevating the chances of successful drug approvals. Moreover, AI holds the potential to curtail development costs by streamlining research and development processes. Machine learning algorithms aid in experimental design and can foresee the pharmacokinetics and toxicity of drug candidates, allowing for the prioritization and refinement of lead compounds, thereby reducing the necessity for extensive and expensive animal testing. Personalized medicine initiatives can be advanced through AI algorithms analyzing real-world patient data, culminating in more efficacious treatment outcomes and enhanced patient compliance. This comprehensive overview delves into the diverse applications of AI in pharmaceutical drug discovery, dosage form design for drug delivery, process refinement, testing, and pharmacokinetics/pharmacodynamics (PK/PD) investigations. It provides a glimpse into various AI-driven methodologies employed in pharmaceutical technology, shedding light on their advantages and limitations. Nonetheless, sustained investments in and exploration of AI within the pharmaceutical sector present promising avenues for enhancing drug development processes and patient care.
Novel Drug Delivery Systems: An effective platform for Enhanced Therapy
Authors: Chinthaginjala Haranath , Repollu Maddileti , Naik Bhukya Babji
Published: October 2024

Modern developments in drug pharmacokinetic and Pharmacodynamics behavior make developing the optimal drug delivery method more rational. It is already clear that future success in medication delivery research will mostly come from interdisciplinary collaborations. Pharmaceutical businesses stand to gain enormous commercial potential and advance human disease treatment by employing better drug delivery methods to make therapeutic agents safer and more effective. It is already apparent that multidisciplinary efforts will mostly be responsible for future success in drug delivery research. Any therapeutic agent that can be made safer and more effective while using an enhanced drug delivery method represents a step forward in the treatment of human diseases as well as significant marketing potential for pharmaceutical companies. The best drug delivery systems, based on the etiology and physiological requirements of the body, deliver a predefined dose of medication to the intended site at the appropriate time and place. The speed at which a medication reaches its intended location cannot be controlled by conventional pharmaceutical dosage forms. Novel drug delivery systems (NDDS) are carriers that maintain the drug concentration in the therapeutic range for longer periods of time and may also deliver the content to the targeted site if desired and as needed, because higher doses often cause serious side effects during treatment. Because of this, therapeutic dosages for drug dispersion in non-target tissue and bodily fluids may be far higher than those needed in target cells.
ОНЛАЙН МААЛЫМАТ КАРАЖАТТАРЫНЫН МАЗМУНУ ЖАНА АУДИТОРИЯСЫ
Authors: Дуйшонбаева Аида Байышевна , Сатыбалдиева Чыныхан Топчубаевна
Published: October 2024

Азыркы массалык маалымат каражаттарынын техникалык негизин санариптик жана компьютердик технологиялар түзгөндүгүнүн натыйжасында, алардын социалдык-саясий функционалдуулугу өзгөрүүгө дуушар болууда.  Ал эми макалада эгемендүү  Кыргыз Республикасындагы онлайн-массалык маалымат каражаттарынын заманбап аудиториясы, мазмуну жана экономикалык талаасы каралып талдоого алынды. Интернет маалымат каражаттарына өтүү жараяны дал ушул онлайн маалымат каражаттарына тиешелү экендигин көрүгө болот. Интернеттин  Жалпыга Маалымдоо Каражаттарынын мазмунунун жана  тенденцияларын аныктоо үчүн, “Chalkan.kg” жана “Gezitter.org” маалымат сайттарынын базасында кароо мүмкүн болду. Андан башка Маалыматтык жазуунун популярдуу жанрынан тышкары, онлайн медиада кайра жазуу жана копирайтинг деп аталган кеңири таралган техногендү маалымат каражаттарынынын тарыхы көрсөтүлдү.
КЫРГЫЗ КООМУНДАГЫ ШАЙЛОО ТАЖРЫЙБАЛАРЫ ЖАНА АЗЫРКЫ КӨЙГӨЙЛӨРҮ (САЯСИЙ-СОЦИОЛОГИЯЛЫК ТАЛДОО)
Authors: Жусубалиев Абдикайым Рысбаевич , Патиев Нурканбек Маматович
Published: October 2024

Макалада XIX кылымдын экинчи жарымында Кыргызстандын азыркы территориясы падышалык Россиянын курамына каратылгандан кийин  административдик-саясий башкаруу системасындагы өзгөрүүлөр, киргизилген жаңы башкаруу системасы менен байланышкан саясий өзгөрүүлөр, болуштук шайлоо практикасы талдоого алынган. Анда бул саясий өзгөрүүлөрдүн калктын аң-сезимине, анын жашоо образына, социалдык түзүлүшүнө тийгизген таасирлери каралган. Падышалык бийлик административдик башкаруунун ынтаа коюп иштеген жергиликтүү калктын өкүлдөрүнүн чинин көтөрүү, мураска калтыруу укугу менен пайдаланууга жерлерди берүү, ардак наамдарын ыйгаруу, орден, медалдарды тапшыруу сыяктуу кызыктыруучу практикаларды кеңири колдонгон. XIX кылымдын 2-жарымында түптөлгөн кыргыз коомунун мындай саясий түзүлүшү жана башкаруу системасы 1917-жылдан кийинки Кеңеш бийлигинин киргизилишине чейин дээрлик өзгөрбөй сакталып калган. Бул процесстер, шайлоо практикалары кыргыздар үчүн алгачкы шайлоо тажрыйбалары катары тарыхый мааниге ээ болуп, Улуу Октябрь төңкөрүшүнөн кийин да, азыркы эгемендүүлүк мезгилинде да андагы терс тажрыйбалардын таасири башкаруу системасындагы кээ бир мүчүлүштүктөрдүн башаты болуп калган сыяктуу.
ИCХAК ACAН УУЛУ ПОЛОТ ХAНДЫН ДООРУ
Authors: Aлтымышовa Венерa , Aпышовa Чынaргул Кaбыловнa , Тaгaйбековa Aйнурa
Published: October 2024

Эгемендүүлүккө ээ болгондон кийин поcтcоветтик Борбор Aзия өлкөлөрү менен мaмилеcи caяcий, экономикaлык жaнa мaдaний тaрмaктaрдa бaйкaлaрлык жылыштaргa ээ болду. Aлaрдын ортоcундaгы конcтруктивдуу мaмилелерди жaцы шaрттaрдa куруу, бул өлкөлөрдүн мурдaгы мaмилелерин үйрөнүү кечиктирилгиc милдет болуп caнaлaт. Мaкaлaдa Кокон хaндыгы, aндaгы өзөктүү aйрым экономикaлык, caяcий учурлaр боюнчa cөз болот.
ИСХАК АСАН УУЛУ ПОЛОТ ХАН – КОКОН ХАНДЫГЫНЫН ТАРЫХЫНДАГЫ НЕГИЗГИ ИНСАН
Authors: Адышева Назгул Кабылбековна
Published: October 2024

Исхак Асан уулу Полот хан кыргыз тарыхынын маанилүү бөлүгү болгон Кокон хандыгынын тарыхында көрүнүктүү инсан. Ал башкарган мезгилде аскердик чеберчилик менен дипломатиялык мамиленин өзгөчө айкалышын көрсөткън. Анын ишмердүүлүгү хандыктын түптөлүшүнө жана чыңдалышына, кошуна мамлекеттер жана уруулар менен тышкы байланыштарына чоң таасирин тийгизген. Ийгиликтүү аскердик жортуулдардын жана билгич саясаттын натыйжасында Полот хан Кокон хандыгынын аймагын бир топ кеңейтип, аймактык саясат аренасында өз ордун бекемдей алган. Анын мурасы Кыргызстандын жана бүтүндөй Борбордук Азиянын бул доордун тарыхын түшүнүү үчүн негизги элемент бойдон калууда.
КУРМАНЖАН ДАТКА ЖАНА ОРУС ГЕНЕРАЛДАРЫ: КЫЗМАТЫНЫН БААЛАНЫШЫ, СЫЙЛЫКТАРЫ
Authors: Абытов Байболот Капарович
Published: October 2024

Макалада даңазалуу “Алай ханышасы” Курманжан-датканын жана аны менен ар түрдүү мезгилдерде, ар кандай шарттарда карым-катнашта болгон, атактуу  орус гене­ралдары - Россия империясынын Түркстан генерал-губернаторствосунун генерал-гу­бер­на­торлору менен Фергана облусунун аскер губернаторлорунун ишмердүүлүгүн чагыл­дырууга аракет жасалган. Көпчүлүккө маалым болгондой атактуу мекендешибиз Курман­жан-датканын бай өмүр таржымалы, ар тараптуу ишмердүүлүгүнүн бардык тармак­тары жана аспектилери деталдуу түрдө, дээрлик изилденгендей көрүнүп, таасир калты­рат. Бирок дагы да болсо датка айымдын өмүр баянында, айрыкча орус генералдары, Орус империясынын Түркстан генерал-губернаторствосунун жогорку даражалуу аскер чинов­ник­­тери, Россия империясынын согуш министри А.Н.Куропаткин менен болгон жеке мамиле­лери боюнча дагы эле аз изилденген жагдайлар бар. Кызыгууну туудурган  жаг­дайдын би­ри, Курманжан-датканын 1875-76-жылдардагы Кокон хандыгындагы элдик көтөрүлүш­кө болгон мамилеси, көтөрүлүштүн жетекчилеринин бири, акырына чейин согуш­кан, жеңил­генден кийин бөтөн жерде каза болгон уулу Абдылдабек болот. Өзгөчө кызыгуу­ну туудур­ган маселе Курманжан-датканын Россия империясынын расмий сыйлыктарына ээ болуу­су. Ошол эле учурда Орус бийликтеринин кичүү уулу Камчыбекти бажычыларды жок кылганы үчүн өлүм жазасына тартышын, туруктуулук жана сабыр­дуулук менен баштан кечириши, уулдарынын, небересинин Сибирге айдалышы болгон. XIX кылымдын аягында Түркстан генерал-губернаторствосунун бийлик эгедерлерине уулдарын жана небересин меке­нине кайтарууга  көптөгөн өтүнүч менен кайрылган. Өзүнүн жеке аброю, бир катар генерал-губернаторлордун натыйжалуу жардамы менен балдарын, небересин Сибирь сүр­гүнөн бошотуга, өз мекенине кайтарууга жетишкен.
НАУЧНАЯ И ПЕДАГОГИЧЕСКАЯ ДЕЯТЕЛЬНОСТЬ ИСТОРИКА-УЧЕНОГО ТАШМАНБЕТА КЕНЕНСАРИЕВА В ОШЕ
Authors: Арстанов Сабыркул Абдиманапович
Published: October 2024

В данной статье подробно анализируется научная и педагогическая деятельность известного историка и ученого Ташманбета Кененсариева в городе Ош. В статье отражен его вклад в развитие науки и образования в Кыргызстане, в частности, в Ошском государственном университете, а также его достижения в области исторической науки и педагогический опыт. Также подробно рассмотрены научные исследования автора и его работа в Ошском государственном университете, обсуждено их современное общественное и образовательное значение. В статье глубоко изучены научные работы под руководством Т.Кененсариева и результаты его историко-методологических исследований. Также подчеркнута его роль в подготовке научных кадров.
ИСХАК АСАН УУЛУ ПОЛОТ ХАНДЫН ЖЕТЕКЧИЛИГИ АСТЫНДАГЫ КӨТӨРҮЛҮШТҮН ПОСТСОВЕТТИК ТАРЫХНААМАДА ИЗИЛДЕНИШИНИН КЭЭ БИР МАСЕЛЕЛЕРИ
Authors: Алымбаев Жээнбек , Баитова Фарида Турганбаевна
Published: October 2024

Совет мезгилиндеги тарыхнаамада азаттык үчүн күрѳшкѳн элдин аракеттерине баа берүүдөгү  илимий жыйынтыктар партиянын идеологиялык багытына шайкеш келүүсү зарылдык катары саналган.  Элдик кыймылдарга баа берүүдѳ окумуштуулар таптык позициядан карап, совет мамлекетинин негизги урааны болгон “таптык эзүүгѳ каршы күрѳш”, “бай-манаптык”, “буржуазиялык элементтерге каршы күрѳшүү” сыяктуу калыптанган түшүнүктѳрдү колдонушкан. Андан айырмаланып, постсоветтик тарыхнаамадагы изилдѳѳлөрдүн негизги ѳзгѳчѳлүктѳрү катары азаттык кѳтѳрүлүштѳр элдин эркиндикке умтулган аракеттери катары бааланып, анын жетекчилерине элдик баатыр, улуу тарыхый инсан катары баа берүү тенденциясы жүрүп келүүдѳ. 1873-76-жылдардагы Фергана өрөөнүндө болгон элдик кыймылдын мааниси жана ал кыймылдын жүрүшүндөгү Исхак Асан уулу Полот хандын ролу постсоветтик мезгилдеги тарыхнаамада кыргыз, өзбек окумуштуулары тарабынан жаңы көз караштан изилденип, анын натыйжасында бир канча маӊыздуу эмгектер жаралып, макалалар жарык көрдү
The Applicability of Critical Pedagogy in Adult English Language Teaching (ELT)
Authors: Askari Mona , Baumgartner Lisa
Published: October 2024

This paper explores the applicability of critical pedagogy in adult ELT, emphasizing its role in fostering social awareness and change. Critical pedagogy encourages learners to critically examine their social reality, engage in meaningful dialogues, and become active agents for social justice. However, incorporating this approach into adult ELT faces some challenges. This study addresses four major obstacles to critical pedagogy implementation. The four challenges are a) lack of teacher preparation, b) potential risk of misguiding learners, c) cultural barriers in certain countries and regions, and d) insufficient infrastructure for aligning materials and assessment with critical pedagogy. Despite these challenges, evidence from literature and existing successful case studies suggest that critical pedagogy can be integrated inro ELT with thoughtful adjustments. The current paper provides insights for adult English program leaders to overcome such challenges and implement critical pedagogy effectively, thus empowering learners to achieve both linguistic proficiency and social transformation.
Jordanian EFL Students' Views on the Impact of Online Learning on Their Academic Achievement and Self-Motivation
Authors: Alsayed Sandy Fayez , Ta'amneh Issam Mostafa
Published: October 2024

The research aims to explore Jordanian EFL students' views on the impact of online learning on their academic achievement and self-motivation. The study involved 1776 EFL participants from Al-Zaytoonah, Isra, and Middle East Universities in the academic year 2023-2024, out of which 388 were chosen randomly for sampling. Data gathering was facilitated through a validated survey, distributed both digitally via Google Forms and in printed forms. Collected responses were organized in Excel for analysis. The analysis process involved evaluating the data, focusing on participant demographics, and using frequency and percentage metrics. Both academic performance and self-motivation dimensions were evaluated through mean values, standard deviations, and the MANOVA test. The initially used 5-point Likert scale was restructured into three categories: low, moderate, and high. The results indicate a middle-range influence on the investigated domains, with academic performance taking a slight lead. Key influencing factors identified were gender and GPA. The effect of online learning on student outcomes was diverse, positively impacting collaboration, preparedness, and overall performance but showing limitations in areas like time management and assignment submission. Even though students expressed contentment in collaborative areas, the research highlighted gaps in intrinsic motivation and perceived relevance of tasks.
Legislation of the Russian Federation in the field of industrial safety
Authors:   Lipetsk State Technical University, Makurin P.S.
Published: October 2024

Subject. The article is devoted to the analysis of the existing legislation in the field of industrial safety in the Russian Federation. The goal. The aim is to identify the main regulatory legal acts in the field of industrial safety in the Russian Federation. Method or methodology. The research includes methods of logical, systemic, comparative and structural-functional analysis. Results of the work. The main result of the study is the analysis of legal acts defining the rights and obligations of employees, officials and managers of enterprises and organizations where there are hazardous industries. Conclusions. The regulatory framework presented in the framework of the study regulates the activities of industrial enterprises, but, taking into account the development of modern technologies, it should be developed and updated.
Analysis of the state of franchises in the city of Lipetsk on the example of a barbershop
Authors:   Lipetsk State Technical University, Fedkova O.D. , Glotov D.S. ,   Lipetsk State Technical University
Published: October 2024

Subject. The article is devoted to the activity of the system of the market of franchising services in Russia. Goal. The main purpose of the study is to identify the features, prospects for the development of franchising in the service sector. The tasks to be solved in the course of the work: to study the history of the emergence of franchising, to study the specifics of the barbershop format, to assess the demand for such a business, to analyze competition according to the «5 competitive force method». Method or methodology. The theoretical and methodological basis of the study were the works of domestic and foreign authors in the field of franchising in the service industries of the business sector. The results of the work. An analysis of macro-environment trends showed that the market is characterized by the emergence of a large number of new players in different price segments, as well as price differentiation within large networks, which leads to increased competition for the consumer. Conclusions. The conclusion is to identify the main features of franchising in the service sector.
Social Studies Teachers' Opinions on the Use of Augmented Reality in the Education of Gifted Students
Authors: Ak Çoban Duygu , Oruç Şahin
Published: October 2024

The aim of this study is to reveal social studies teachers' opinions on the use of Augmented Reality in the education of gifted students. As part of the research, a qualitative study was conducted with teachers experienced in the education of gifted and talented students working in BİLSEM and various schools in Istanbul regarding the use of Augmented Reality. Due to the qualitative nature of the study, semi-structured interviews were conducted with 20 Social Studies teachers. The research was conducted within the scope of Social Studies and gifted and talented education during the 2023-2024 academic year. A descriptive content analysis was used to thoroughly examine the data. According to the findings from the interviews, the teachers are knowledgeable about augmented reality. Additionally, the results indicate that the use of augmented reality in the education of gifted and talented students strengthens skills such as permanent learning, capturing attention, increasing motivation, rapid learning, critical and creative thinking, developing perspective, and problem-solving.
The Use of Geographic Information Systems and Multi-Criteria Decision-Making Methods in the Creation of Forest Fire Susceptibility Maps: A Literature Review
Authors: Küçükarslan Ali Bahadır , Köksal Mustafa , Ekmekçi İsmail
Published: October 2024

Forest fires are natural disasters that cause significant environmental, economic, and social damage worldwide. This study provides a literature review examining how Geographic Information Systems (GIS) and Multi-Criteria Decision-Making (MCDM) methods are utilized in the prevention of forest fires and the identification of high-risk areas. GIS, as a system used for the collection and analysis of spatial data, enables the consideration of various factors influencing fire risk, such as climate change, topography, vegetation, and weather conditions. The spatial analysis capabilities offered by GIS play a critical role in identifying regions with high fire susceptibility when generating fire risk maps. Additionally, MCDM methods contribute significantly to the decision-making process by allowing the evaluation of multiple criteria in fire risk analysis. Logistic Regression and Frequency Ratio, which are frequently employed in the literature, are widely used in fire risk analysis and improve the accuracy of susceptibility maps. Furthermore, MCDM methods have been proven effective in estimating the likelihood of forest fire occurrences and identifying fire-prone areas. The integration of GIS and MCDM methods allows for more precise identification of risk zones and supports the development of fire prevention strategies. This literature review highlights the advantages of utilizing GIS and MCDM in the production of forest fire susceptibility maps and suggests that these methods may have broader applications in future research. The effective use of technology in combating forest fires enhances the accuracy of fire risk assessments, contributing significantly to environmental protection efforts.
臺灣精準運動科學研究發展現況與未來展望
Authors: 江佩穎 江佩穎
Published: October 2024

目的：運動科技研究及產業應用是目前臺灣主要推動的政策項目之一，國科會人文處推動「精準運動科學研究專案計畫」，支援及促進臺灣各學術領域參與運動科學及運動科技的研究風潮。本文目的在藉由分析國科會人文處運動科學研究相關專案計畫推動歷程，闡述臺灣精準運動科學研究的精神、推動策略、推動成效等面向，並提出精準運動科學研究的未來展望。結果：「精準運動科學研究專案計畫」立案精神為知識轉譯，將實驗室所進行的科學研究成果轉譯成教練與選手、運動產業、社會大眾可用的知識；著重跨領域研究、產學研合作、成果落實應用、擴散運科知識等推動策略；推動成效除學術報告外，更強調運科技術產品研發成果、運動員轉譯成果、社會大眾轉譯成果。民國107-111年推動之第1期「精準運動科學研究專案計畫」著重於教練與選手的成果轉譯，業已順利完成；現正進行著重於運動產業成果轉譯的第2期「精準運動科學研究專案計畫」(民國112-115年)，期待未來展望於臺灣運動文化研究、創新性運動科技研究、運動心理研究、永續運動生態研究…等，成果轉譯能全面擴展至社會大眾，以建構具臺灣特色及價值的全民健康運動生態系。

 

Purposes: The research and industrial application of sports technology is one of the major policy initiatives currently promoted in Taiwan. The “Precision Sports Science Research Project” which supports and encourages various academic fields in Taiwan to participate in the sports science and technology research. This article aims to analyze the progress of sports science research projects of the National Science and Technology Council (NSTC), elucidating aspects such as the spirit, promotion strategies, and outcomes of Taiwan’s precision sports science research, while also proposing future prospects for this research area. Conclusions: The foundational concept behind the "Precision Sports Science Research Project" is knowledge translation, which aims to transform scientific research outcomes from laboratories into practical knowledge for coaches, athletes, the sports industry, and the general public. The project emphasizes interdisciplinary research, industry-academia collaboration, results application, and sports science knowledge dissemination. In addition to academic reports, the outcomes emphasize the development of sports technology products, the translation of research findings for athletes and the public. The first phase of the "Precision Sports Science Research Project" (2018-2022) focused on the translating results for coaches and athletes and has been successfully completed. The second phase (2023-2026) is currently underway, which focuses on translating results for the sports industry. Future prospects for Taiwan might include research in sports culture, innovative technology, sports psychology, and sustainable sports ecology, with the aim of building a Taiwan-specific, value-driven ecosystem for public health and sports.

 
羽球競賽資料文獻分析與實務訓練應用
Authors: 王志全 王志全 , 廖偉成 廖偉成
Published: October 2024

目的：運動競賽資訊的數據分析是評估選手運動表現和訓練處方的重要參考依據。羽球運動在2006年實施21分新賽制後，雖有相關研究針對新賽制競賽資料進行分析，但少有文章有系統的進行統整與歸納，使得相關研究結果資料的解釋與應用受到限制，而降低了資料的可用性。因此，本研究目的係以系統性文獻回顧，分析羽球五個單項的競賽資料結果，並依此結果進行討論和提出具體實務訓練建議，作為科學化訓練和提升運動表現與降低運動傷害之重要參考依據。方法：本文以Google學術搜尋、PubMed和華藝線上資料庫進行文獻檢索，經由排除非收錄在SSCI、SCI及TSSCI資料庫之論文，以及研究對象為非頂尖運動員和非真實競賽分析資料後，共計有8篇外文文獻，1篇中文文獻。結果：回顧相關文獻後發現，羽球五個單項的競賽結構會有差異，而造成差異主因是選手性別的不同，其中男子選手的競賽會有較快節奏和高強度的比賽，而女子選手的競賽則是會有較多的來回拍數，且羽球五個單項競賽結構內容在平均每回合擊球時間和休息時間皆有增加的趨勢。結論：羽球實務訓練應依五個單項和選手性別不同，安排差異和特殊性訓練安排，同時必須定期關注分析羽球競賽資料的發展與知識更新，以利訓練更符合實際競賽需求和提升訓練成效。

 

Purpose: Data analysis is crucial for assessing athletic performance and prescribing effective training regimens. While previous studies have explored competition data following the implementation of badminton’s 21-point scoring system since 2006, there is a lack of comprehensive integration of these results. This gap impedes the interpretation and application of research data, limiting its overall utility. Therefore, this study conducts a systematic literature review to analyze competition results across the five individual badminton events. The aim is to provide practical training recommendations based on these results, serving as a valuable reference for optimizing scientific training, enhancing sports performance, and reducing sports injuries. Methods: This article employed Google Scholar, PubMed, and the Airiti library online database for literature retrieval. Studies not included in the SSCI, SCI, and TSSCI databases, as well as those did not analyze real competition data from elite athletes, were excluded. The final selection included 8 international and 2 Chinese literature. Results: Previous studies reveal differences in competition structure across the five events, primarily attributed to player gender. Men’s competitions tend to be faster-paced and more intense, while women’s competitions involve longer rallies. An upward trend was observed in the average rally duration and rest time across the five events. Conclusion: This study highlights the importance of tailored training to address the distinct differences in the competition structures of men’s and women’s badminton events. Continuous monitoring of badminton competition data is essential to ensure training aligns with current competition demands, ultimately enhancing performance. Regular updates in badminton competition data analysis are crucial for ensuring that training regimens meet competition needs.

 
Far from the Madding Crowd at 150: Seven Reflections
Authors: Guiliano Edward , Henchman Anna , Hennessy Jr. Mark M. , Jackson Jeffrey Edward , Jenkins Melissa Shields , Kim Jane E. , Lorentzen Eric G. , Yamboliev Irena
Published: October 2024

Seven scholars of Victorian literature reflect on Thomas Hardy’s Far from the Madding Crowd in honor of the 150th anniversary of its publication. The authors reflect their personal responses to the novel, and each has a unique focus.