bluuebunny/crossref_metadata_2025 huggingface dataset:
ANTERIORUVEITISREVEALING MULTIPLE SCLEROSIS
Authors:   Ophtalmology A, Hopital des Specialites De Rabat., Tabchi Manal , Hmeimett Zeinabou ,   Ophtalmology A, Hopital des Specialites De Rabat., Lazaar Hamza ,   Ophtalmology A, Hopital des Specialites De Rabat., a Tahaboutaj ,   Ophtalmology A, Hopital des Specialites De Rabat., Amazouzi Abdallah ,   Ophtalmology A, Hopital des Specialites De Rabat., Boutimzine Noureddine ,   Ophtalmology A, Hopital des Specialites De Rabat., Ouafa Cherkaoui Lalla ,   Ophtalmology A, Hopital des Specialites De Rabat.
Published: November 2023

Multiple sclerosis is a chronic demyelinating disease of the central nervous system (1). It is often revealed by optic neuropathy(2). However, other ocular manifestations may be associated with multiple sclerosis, notably uveitis (2). We report the case of a patient who consulted for anterior Granulomatous uveitis and whose clinical and para-clinical examination revealed multiple sclerosis.
DIFFICULTIES IN IMPLEMENTING THE HALAL TRACEABILITY SYSTEM AMONG IMPORTED HALAL MEAT SUPPLIERS
Authors:   Academy of Contemporary Islamic Studies, Universiti Teknologi MARA,40450 Shah Alam, Selangor, Malaysia., Nurul Syuhadah Binti Awang Rajie Dayang , Huda Sahari Noorul ,   Academy of Contemporary Islamic Studies, Universiti Teknologi MARA,40450 Shah Alam, Selangor, Malaysia., Samori Zakiah ,   Academy of Contemporary Islamic Studies, Universiti Teknologi MARA,40450 Shah Alam, Selangor, Malaysia.
Published: November 2023

Nowadays, a lot of halal related issues arouse a bad image to religion and many parties includes halal industry players and consumers, directly or indirectly. The meat cartel scandals issuehas shocked Malaysia in the previous year. In conjunction to the issue, many Muslim consumers had lost their confidence towards the consumption of halal meat imports. The unfolding scandal over fake halal documentation, fake halal logos, and fake halal meat has really affected the halal meat import industry since consumer confidence is decreasing and honest businesses are working hard to convince customers of their compliance with halal requirements. Transparency in the implementation of a halal traceability system on the meat import supply chain helped prevents any violations or fraudulent cases. The aims of this studyis to discover the challenges of implementing a halal traceability system among halal meat import suppliers. This research adopts a qualitative method and the data was collected through a semi-structured interview. The thematic analyses was conducted on transcribed and coded data interview. The results of the study showed that time consumption, cost implementation, and lack of digital expertise have become challenges for halal meat import suppliers in implementing a halal traceability system.
ACTUALIZATION OF PANCASILA VALUES IN PREVENTION AND ERADICATION EFFORTS NARCOTICS ABUSE IN INDONESIA
Authors:   Doctoral Student in Law, Faculty of Law, University of Lampung, Indonesia., Susanto Gatot , Rifai Eddy ,   Doctoral Lecturer in Law, Faculty of Law, University of Lampung, Indonesia., a Maroni ,   Doctoral Lecturer in Law, Faculty of Law, University of Lampung, Indonesia., Siswanto Heni ,   Doctoral Lecturer in Law, Faculty of Law, University of Lampung, Indonesia.
Published: November 2023

Pancasila is a state ideology that has been agreed upon as the basis for organizing social, national and state life in Indonesia. The practice of Pancasila values will certainly lead to the development of a society that is devout, humane, united, democratic and just. On the other hand, weak understanding and implementation of these basic values will cause various disorders that can threaten all areas of life, one of which is narcotics abuse. Sanctions or punishments for those who abuse narcotics themselves are different from dealers, couriers, dealers, and so on, because in the Narcotics Law there is a grouping of narcotics crimes. This is in accordance with the double trick system adopted by the Narcotics Law. Actualizing the values of Pancasila in efforts to prevent and eradicate narcotics abuse cannot be separated from the awareness of the entire community and law enforcement officials, in this case judges, in deciding narcotics abuse cases for the sake of justice based on God. This is because the values of Pancasila maintain the credibility of Indonesian culture and attitudes and have a major impact on the life and character of the nation by fighting narcotics abuse and breaking the chain of narcotics problems. We must understand the meaning of Pancasila values correctly, Pancasila as Indonesias national ideology for unity, as a national standard for preventing and eradicating narcotics abuse. The related Pancasila values are the value of God, the value of humanity, the value of unity, the value of people and the value of justice, so in everyday life you must adhere to these five precepts in order to avoid the dangers of narcotics.
ASSESSMENT OF ACADEMIC LEADERSHIP PRACTICES IN PUBLIC UNIVERSITIES IN NIGERIA
Authors:   Post Graduate Student, Department of Educational Management and Foundations, Delta State University Abraka, Nigeria., Patience OKORO , Nelson E. AKPOTU ,   Department of Educational Management and Foundations, Delta State University Abraka, Nigeria., Romina I. ASIYAI ,   Department of Educational Management and Foundations, Delta State University Abraka, Nigeria.
Published: November 2023

This study focused on evaluating the academic leadership practices within public universities in Edo and Delta States, Nigeria. Its primary objective was to identify the different types of academic leadership practices prevalent in these states. The research design employed was ex post facto, with a target population of 1,957 junior academics. A sample of 375 junior academics was selected using the simple random sampling technique, and data collection relied on a questionnaire. The analysis was carried out using mean and standard deviation, with a benchmark set at 2.50 for acceptability. The results of the analysis unveiled the existence of five distinct forms of academic leadership practices among academic leaders in federal and state universities in Delta and Edo States. These five forms included: stirring common academic vision leadership practice (SCAVLP), promotion of academic relationship leadership practice (PARLP), provision of academic feedback leadership practice (PAFLP), encouraging academic advancement leadership practice (EAALP), and academic mentorship leadership practice (AMLP). Among these, academic mentorship was found to be the least commonly observed form of academic leadership practice among the five identified in the study. In light of these findings, the study recommends that university management should initiate a mentorship program to educate all staff on the principles and concepts of mentorship. Additionally, junior academics should be formally assigned to senior academics for mentorship purposes.
A CREATIVE ODYSSEY TO HEALING AND SELF DISCOVERY
Authors: Purohit Aarushi
Published: November 2023

In a world where stress and mental health concerns are prevalent, the practice of art therapy has emerged as a powerful means of healing and self-discovery. This article explores the transformative potential of art therapy as a form of psychotherapy that employs creative expression to address emotional struggles and promote well-being. Unlike traditional talk therapy, art therapy allows individuals to communicate through visual art, providing a safe space to explore complex emotions and inner conflicts. Through artistic creation, individuals delve into their subconscious, guided by trained art therapists who interpret the symbolism within the artwork. Research highlights its therapeutic impact, reducing stress, enhancing emotional resilience, and fostering empowerment. Art therapy is practiced in diverse settings, benefiting populations from children with developmental disabilities to trauma survivors. It serves as a tool for personal growth and self-exploration, contributing to mindfulness and relaxation. As the importance of mental health gains global recognition, art therapy is expected to integrate more comprehensively into mainstream treatments, offering profound hope in navigating the complexities of the human experience. Art therapy underscores the enduring power of creativity and self-expression, providing a dynamic platform for healing and personal growth.
EXPLORING THE MEDICINAL MARVEL: THE POTENTIAL OFYARSAGUMBA AS REGENERATIVE MEDICINE AND IN WOUND HEALING
Authors:   College of Pharmacy, B-pharmacy, RIMT University, Mandi Gobindgarh, Punjab (147301), India., Kumar Gupta Sumit , Kumar Mali Sushil ,   College of Pharmacy, B-pharmacy, RIMT University, Mandi Gobindgarh, Punjab (147301), India., Prakash Yadav Ram ,   College of Pharmacy, B-pharmacy, RIMT University, Mandi Gobindgarh, Punjab (147301), India., Sohi Shaheena ,   College of Pharmacy, Associate Professor, RIMT University, Mandi Gobindgarh, Punjab (147301), India.
Published: November 2023

Yarsagumba(Cordyceps mushroom) a valued herbal medicine, is a fungus that grows on ghost moth larvae. It belongs to the Ophiocordycipitaceae family and has been used in traditional Chinese medicine for centuries. It has various applications in the pharmaceutical and health industries. In Nepal, Yarsagumba has been recognized for thousands of years and is considered one of the most promising medicinal mushrooms. Scientists have been studying its unique life cycle and medical uses for the past 30 years.However, once correctly identified, these enigmatic organisms hold great promise in the prevention and treatment of numerous ailments such as cancer,woundhealing, antidiabetic, alleviating fatigue, respiratoryproblems, and erectile dysfunction in men.Cordyceps fungi possess significant phytochemicals, namely cordycepin and adenosine, which function by suppressing the adenosine A2 receptor and consequently inhibiting various neuroinflammatory markers such as NF-ÎºB, NLRP3 inflammasome, IL-1Î², iNOS, COX-2, TNF-Î±, and HMGB1. Yarsagumbas wound healing properties are multifaceted, with its anti-inflammatory and antioxidant compounds reducing inflammation and preventing tissue damage. Its immunomodulatory effects enhance the bodys immune response and inhibit the growth of harmful microorganisms, reducing the risk of infection. Yarsagumbas regenerative capabilities stimulate collagen production and promote angiogenesis, resulting in improved wound healing outcomes and minimized scarring. This review examines how Yarsagumbas bioactive compounds can enhance wound healing, reduce scarring, and improve tissue repair. It also explores the plants regenerative properties, such as its ability to stimulate stem cell growth and differentiation. Our findings indicate that the activation of adenosine receptors by adenosine and cordycepin effectively triggers the Wnt/Î²-catenin signaling, which can potentially facilitate tissue remodeling and serve as a therapeutic approach for skin wound treatment.
Anti-lipidemic and protein restoration potential of Monodora myristica (Gaertn.) in rats fed with cassava containing crude oil
Authors: Okpoghono Joel , Ukperegbulem Jonah Kanayo , Igue Udoka Bessie
Published: November 2023

Consumption of cassava meal affected by crude oil has significant effects on lipid and protein metabolism. The hepatoprotective action of spices is mostly attributed to the suppression of lipid oxidation and protein breakdown. This study examined the protein restoration and anti-lipidemic potential of Monodora myristica (Gaertn.) in rats fed with cassava contaminated with crude oil.

The research involved 36 albino rats separated into six groups (n = 6). Group 1 (control) consumed cassava without crude oil. Group 2 received cassava with crude oil. Groups 3, 4, and 5 fed on cassava with crude oil and various extracts of M. myristica, i.e., aqueous, ethanol, and diethyl ether, respectively. Group 6 received non-ionic synthetic surfactant Tween 80. The experiment relied on standard methods.

Blood serum and liver obtained from the rats of Group 2 showed a significant (p < 0.05) increase in total cholesterol, low density lipoprotein cholesterol, triacylglycerol, and malondialdehyde, as well as a decrease in total protein, albumin, and high-density lipoprotein cholesterol. The groups that received M. myristica extracts showed a significant increase (p < 0.05) in total protein, albumin, and high-density lipoprotein cholesterol. They also had lower total cholesterol, low density lipoprotein cholesterol, triacylglycerol, and malondialdehyde as compared to Group 2, which dieted on cassava contaminated with crude oil without additives.

In this research, crude oil-contaminated cassava affected proteins and lipids in rats. Diethyl ether extract of M. myristica demonstrated the best anti-lipidemic and protein restoration.
Determinants of the successful signing of public–private partnership contracts for water and sanitation infrastructure financing in Zimbabwe
Authors: Mundonde Justice , Makoni Patricia Lindelwa
Published: November 2023

The private sector remains hesitant to invest in water and sanitation infrastructure in Zimbabwe. For policymakers and investors, it is pertinent to understand the factors that determine the signing of water and sanitation public–private partnership (PPP) contracts, in order to leverage expertise and resources to achieve the Sustainable Development Goal targets. This study applied count econometrics on data collected for the 25 years from 1996 ending in 2021, with the aim of investigating the determinants of the number of PPP contracts signed in Zimbabwe. Poisson regression estimations identified positive macroeconomic prospects, financial market development, and strong institutional governance environment as important determinants for PPP contracting in Zimbabwe. The number of PPP contracts is further confirmed to be dependent on the availability of inward foreign direct investment flows. The influence of institutional governance quality on the number of water and sanitation PPP contracts was tested using a composite index constructed using the principal components analysis technique. It is advised that the government of Zimbabwe should strengthen their governance institutions and further develop their capital and bank credit markets, so as to attract investors to take up the water and sanitation infrastructure PPP contract opportunities available in the country.
The influence of socioeconomic and spatial variables on total maximum daily load progress in the United States
Authors: Gunawardana Charitha , McDonald Walter
Published: November 2023

The total maximum daily load (TMDL) program requires each state in the United States to assess their water bodies, list those that are impaired, and develop TMDL plans or programs to restore them. However, the impact that spatial and socioeconomic variables have on TMDL progress is unknown. This study seeks to fill this gap through a nation-wide analysis of the influence of spatial and socioeconomic variables on indicators of TMDL progress. To do so, data were collected and analyzed for each state, including indicators of TMDL progress, spatial variables, and socioeconomic data. Then, these data were applied to identify overall trends and to define the relationships between indicators of TMDL progress and spatial and socioeconomic variables. Results indicate that the size of a state, the length of total streams, and median household income are related to the percentage of streams that are assessed within a state. In addition, states largely followed similar patterns in TMDL progress based on the US Environmental Protection Agency region that they were within, indicating that location plays a large role. Overall, this study helps to contextualize progress in TMDL development and aid in our understanding of factors that influence the implementation of water quality programs.
Measuring the effectiveness of an integrated algae bloom, T&O, and cyanotoxin monitoring program
Authors: Adams Hunter , Southard Mark , Reeder Sam , Appleton Emily , Nix Daniel
Published: November 2023

The City of Wichita Falls (CWF) Cypress Environmental Laboratory (CEL) established an integrated monitoring program in response to extreme taste and odor (T&O) events in 2016. The program uses field monitoring with sondes, sensory analysis to describe types of odors, water quality bench testing, algae/cyanobacteria identification and enumeration by flow-imaging microscopy, actinomycetes culturing, T&O detection by gas chromatography-mass spectrometry (GC-MS), cyanotoxin screening by quantitative polymerase chain reaction (qPCR), and cyanotoxin detection by fluorometry. To date, the CEL had detected 16 T&O events prior to finished tap being discharged to the distribution system. This has allowed utility staff to take proactive measures to mitigate events, which has virtually eliminated consumer T&O complaints. This article provides a brief history of T&O analysis, means to monitor and mitigate blooms, T&O compounds, and cyanotoxins, and measures the effectiveness of the CEL's monitoring program by evaluating each T&O event, and specifically geosmin.
Tin Oxide Nanoparticles: A Review
Authors: Kumar Aashish , Chitkara Mansi , Thakur Renu
Published: November 2023

The aim of this review article is an overview of the tin oxide (SnO2) nanoparticles, and the
literature addresses the existing research related to the various modifications and characterization of
SnO2 nanoparticles with their physicochemical investigations. Among various metal-oxide nanoparticles, SnO2 nanoparticles are considered one of the potential candidates for electronic and electrical
device fabrication, sensors, display devices, gas sensing, photovoltaic devices, LIBs (Lithium-ion
batteries), photocatalysis and optoelectronic devices, supercapacitors, SnO2 nanowires would provide
electrolyte channels for effective transport, catalyst, and anode materials. Apart from their technological supremacy, SnO2 nanoparticles have demonstrated their compatibility with human cervical cancer cells and have successfully achieved hyperthermia temperature when subjected to an alternating
current magnetic field. Doping with some of the potential rare-earth dopants via various synthesis
methods such as Chemical co-precipitation, sol-gel, polymeric precursor method, and nebulizer spray
pyrolysis method is the major highlight of this review article. As per the requirement of the system,
SnO2 nanoparticles can be tuned by size, shape, and functionality.
La teoría del actor-red: una herramienta para la comprensión de la conservación de los maíces locales en la región Frailesca, Chiapas, México
Authors: Fonseca-Flores María de los Angeles , García-García Antonio , Márquez-Rosano Conrado , Parra-Vázquez Manuel Roberto
Published: November 2023

La conservación de los maíces locales (CML) en la región Frailesca, Chiapas, México, interactúa con una creciente materialidad tecnológica, sin embargo, son escasos los estudios para comprender la dinámica de redes sociomateriales que la conforman. Por eso, el objetivo de esta investigación es valorar el potencial de la teoría del actor-red (TAR) para comprender la complejidad sociotécnica de la cml. A partir de su perspectiva metodológica, “seguir a los actores”, se realizaron 33 entrevistas a campesinos que conservan maíces locales en tres ejidos de la región para describir y entender, a partir de sus explicaciones, las conexiones y las mediaciones entre entidades diversas. El resultado demuestra el potencial de la tar para valorar la complejidad sociotécnica de la cml dada a través de asociaciones y reasociaciones en la práctica de conservación. En particular, con objetos técnicos que, junto a otras entidades de cualquier naturaleza, influyen en la estabilidad de la CML frente a las tensiones crecientes para preservar la base de la subsistencia campesina. Se concluye que el análisis sociotécnico de la cml aporta a la comprensión de sus transformaciones y desplazamientos en una región impactada por la modernización agrícola; además que se necesita profundizar en la utilidad de la tar para proponer configuraciones heterogéneas de humanos y no humanos a favor de la sustentabilidad de la CML.
Solve single photon detector problems
Authors: Shu Hao
Published: November 2023

Single photon detector(SPD) problems arise in most quantum tasks, especially for measuring states going through high-lost channels. They are particularly prominent in quantum key distribution(QKD), which could be the most significant application in quantum information theory. In recent years, QKD distance has been improved dramatically but is still restricted because the bit error rate(QBER) caused by SPD dark counts will be out of control as the distance increases. If this problem can be solved, QKD can be implemented over arbitrarily long distances. However, previous solutions often result in impractical requirements such as superconductors while they can only reduce the dark count rate to finite low levels. In this paper, we solve SPD problems with today's technologies only. Although it is the no-cloning theorem that prevents a state from being measured multiple times to obtain a more reliable result, we propose a scheme circumventing the no-cloning theorem in certain tasks to allow a single state to be employed several times. The scheme demonstrates that imperfect detectors can provide nearly perfect results, namely, the QBER caused by dark counts can be reduced to arbitrarily low while in the meantime, detective efficiency can be improved to arbitrarily high. Consequently, QKD distance is not limited by the imperfect SPD anymore and can be improved from hundreds of kilometers to thousands without high-technology detectors. Furthermore, similar schemes can be applied for reducing measurement errors or improving the performance of sources. Finally, it is worth noting that although the paper is mainly discussed in the context of QKD, our scheme is an independent scheme that could be employed in other protocols wherever SPD are employed.
Contribuição da Tecnologia Digital para a Técnica Cirúrgica de Inserção de Mini-Implantes: Uma Revisão de Literatura
Authors: Honsali Yasmina El , Mohimd Hajar Ben , Zaoui Fatima , Benyahia Hicham
Published: November 2023

Mini-implantes ortodônticos são usados ​​para obter uma ancoragem segura. Sua técnica de inserção é simples, mas deve ser precisa para evitar complicações intra e pós-operatórias. Este estudo teve como objetivo revisar a literatura sobre o papel da tecnologia digital na colocação precisa de mini-implantes e descrever as diferentes etapas da cadeia de fabricação do guia de inserção. As bases de dados utilizadas foram PubMed, Science Direct e Google Scholar, incluindo os seguintes descritores em inglês: “Orthodontic Anchorage Procedures”, “Cone Beam Computed Tomography”. A tecnologia digital melhora a precisão da colocação dos mini-implantes usando imagens 3D para avaliar a quantidade e qualidade do osso e a proximidade das estruturas anatômicas na área a ser implantada. Ao combinar imagens 3D com as novas técnicas de impressão 3D e planejamento virtual, o ortodontista pode obter um guia de posicionamento personalizado para o paciente usando técnicas de design e fabricação auxiliadas por computador. Um sistema de inserção de mini-implantes assistido digitalmente é uma técnica promissora, mas não pode ser usado rotineiramente. Portanto, são necessários estudos em larga escala para mapear a inserção dos mini-implantes em diferentes áreas, considerando etnia, gênero e diferentes características anatômicas.
Queilite actínica (“Lábios de Marinheiro”): uma Revisão para o Clínico
Authors: Mattos Maria Vitória , Honorato Júlia , Leite Ana Flávia Schueler de Assumpção , Oliveira Silvia Paula de , Lourenço Simone de Queiroz Chaves
Published: November 2023

A Queilite Actínica (QA), também conhecida como “lábios de marinheiro”, é uma patologia com potencial de malignização e, ainda que seja de fácil diagnóstico e prevenção, casos diagnosticados tardiamente podem evoluir para carcinoma de lábios. Seu principal fator etiológico é a exposição aos raios ultravioletas, e por este motivo, indivíduos que se expõem muito ao sol, incluindo militares, podem ser considerados grupo de risco para a doença. O objetivo principal deste trabalho foi descrever os principais fatores de risco e prognósticos da QA e apresentar uma revisão para o cirurgião-dentista, facilitando a identificação e conduta. Para tal, foi realizada busca de artigos pertinentes ao tema nas bases de dados Medline, Lilacs, SciELO e PubMed, de 1987 a 2022. O seguinte perfil do paciente com QA foi identificado: homem, na quinta década de vida, pele clara, com lesões no lábio inferior e com histórico de longo tempo de atividades ocupacionais ao ar livre/intensa exposição solar. O cirurgião-dentista possui papel fundamental na identificação dos grupos de risco, no reconhecimento precoce da doença e, em casos mais avançados, realizar o diagnóstico e o correto encaminhamento para atendimento especializado.
The relationship between self-stigma and quality of life in long-term hospitalized patients with schizophrenia: A cross-sectional study
Authors: Chai Jiabao , Liu Fuquan , Deng Hu , Hu Na , Huang Wenqian , Wang Hong , Zhou Xuanzi , Liu Lin , Li Ying
Published: November 2023

Objective: To investigate self-stigma’s influence on
schizophrenia patients’ quality of life and its mediated impact by
various factors. Methods: This study adopted a cross-sectional
design and randomly selected 170 hospitalized patients with
schizophrenia for evaluation. The assessment tools included the Positive
and Negative Syndrome Scale (PANSS), Self-Esteem Inventory (SEI),
Connor-Davidson Resilience Scale (CD-RISC), Internalized Stigma of
Mental Illness Scale (ISMI), Schizophrenia Quality of Life Scale (SQLS),
Coping Questionnaire for Schizophrenia Patients (CQSP), and Social
Support Rating Scale (SSRS). Correlation analysis, regression analysis,
and mediation analysis were used to test the correlation and mediation
effects. Results: Self-stigma had a significant impact on
quality of life (T = 8.13, p = 0.00). Self-esteem (T = -2.11,
p = 0.04) and coping strategies, specifically problem-solving (T
= -2.58, p = 0.01) and avoidance (T = 4.65, p = 0.00),
have a greater impact on self-stigma. When self-stigma is used as a
mediator, the problem-solving factor in coping strategies has an
indirect effect on quality of life, which is significant (AB = -0.16,
P = 0.02), while the avoidance factor in coping strategies has a
direct effect on quality of life, which is significant (C’ = 0.54,
p < 0.001), and an indirect effect, which is also
significant (AB = 0.25, p < 0.001).
Conclusion: Self-stigma has a significant impact on quality of
life. Clinical work to improve the quality of life of patients with
schizophrenia should focus on self-stigma and factors that affect
self-stigma, especially self-esteem and coping strategies.
The risk factors of hemorrhoidal disease： a Mendelian randomization study
Authors: Miaozhi Yu , MZ Yu , Y Shang , LL Han
Published: November 2023

Hemorrhoids are the most common perianal disease, but current
observational studies have yielded inconsistent results in investigating
the etiology. Our further exploration of the etiology will help prevent
the disease. We conducted a two-sample bidirectional Mendelian
randomization (MR) analysis using publicly available genome-wide
association studies (GWAS) statistics from multiple consortia. The
inverse-variance weighted (IVW) method was used for the primary
analysis. We applied four complementary methods, including weighted
median, weighted mode, MR-Egger regression, and Cochrane’s Q value, to
detect and correct the effects of horizontal pleiotropy. Genetically
determined constipation (OR = 0.97, 95% CI: 0.91-1.03, P = 0.28) and
diarrhea (OR = 1.00, 95% CI: 0.99-1.01, P = 0.90) did not have a causal
effect on HEM but stool frequency (OR = 1.28, 95% CI: 1.05-1.55, P =
0.01), waist-to-hip ratio adjusted for BMI (OR = 1.11, 95% CI:
1.06-1.64, P = 1.59×10 ), and order Burkholderiales
(OR = 1.09, 95% CI = 1.04–1.14, p = 1.63×10 ) had
a causal effect on. Furthermore, we found a significant causal effect of
constipation on HEM in the reverse MR analysis (OR = 1.21, 95% CI:
1.13-1.28, P = 3.72×10 ). The results of MR-Egger
regression, Weighted Median, and Weighted Mode methods were consistent
with those of the IVW method. Horizontal pleiotropy was unlikely to
distort the causal estimates, as indicated by the sensitivity analysis.
Our MR analysis reveals a causal association between stool frequency and
waist-to-hip ratio with HEM, despite variations in results reported by
observational studies. Unexpectedly, we found a relationship between the
order Burkholderiales in the gut flora and HEM, although the mechanism
is unclear.
Effects of host competence and schooling behavior on parasite transmission in a fish-gyrodactylid system: test of the dilution effect
Authors: Zhou Shun , Jin Xiao , Duan Ming , Zou Hong , Li Ming , Marcogliese David , Wang Guitang , Li Wenxiang
Published: November 2023

High species diversity in a community may reduce risk of infectious
disease, termed the dilution effect. However, the generality of dilution
effect in different disease systems remains controversial. Besides host
competence, behavior of fish hosts also may play an important role in
dilution or amplification of disease. Using the goldfish (Carassius
auratus)-Gyrodactylus kobayashii system, effects of host competence and
schooling behavior on parasite transmission were investigated while
holding focal host density constant. Following competency tests of 12
fish species as potential hosts for the parasite, infection of G.
kobayashii was determined on fins of goldfish mixed with each one of
three different species based on their level of host competence,
including the silver crucian carp, C. auratus gibelio (low competence),
the grass carp, Ctenopharyngodon idellus (incompetence), the swordtail
Xiphophorus helleri (incompetence), and all four species combined.
Compared with mean abundance (85.8 ± 25.1) on goldfish in the control
group, there was a significant decrease in the silver crucian carp group
(30.0 ± 16.5), but no significant changes in the swordtail group (70.0 ±
22.2), the grass carp group (116.1 ± 33.2), or the multi-species group
(75.9 ± 30.8) during the 10-day experiment. The parasite was also found
on C. auratus gibelio in the silver crucian carp group and the
multi-species group at a mean abundance of 7.1 and 10.9, respectively.
Analysis of swimming behavior showed that the goldfish mixed well in
schools with the silver crucian carp. However, the goldfish maintained
separation from the grass carp and swordtail when mixed together.
Distance between goldfish increased, and swimming speed and contact time
decreased with the additional fish for all groups. The results suggested
that the presence of a low-competence host in sufficient numbers was a
necessary condition for a dilution effect due to encounter reduction,
and the dilution effect may also be enhanced by changes in schooling
behavior of goldfish in the presence of the low competence hosts.
However, the presence of incompetent hosts did not result in any
dilution effect owing to the specialist nature of the parasites and the
lack of mixing with schools of goldfish.
Wyniki ekonomiczne a nakłady inwestycyjne w indywidualnych gospodarstwach rolnych uczestniczących w polskim FADN w zależności od ich typu rolniczego
Authors: Mikołajczyk Jarosław
Published: November 2023

W artykule zaprezentowano wyniki ekonomiczne oraz nakłady inwestycyjne realizowane w gospodarstwach rolniczych uczestniczących w polskim FADN. Celem opracowania było oszacowanie i ocena różnic w działalności inwestycyjnej pomiędzy gospodarstwami różnych typów rolniczych. Wyniki wskazują na silne uzależnienie poziomu wydatków inwestycyjnych od dochodów gospodarstw. Wysoko wyspecjalizowane gospodarstwa ogrodnicze uzyskiwały najwyższe dochody i realizowały wyższe wydatki inwestycyjne. Najniższe dochody, a co za tym idzie także wydatki inwestycyjne, odnotowano w gospodarstwach bez specjalizacji
Wpływ absorpcji środków unijnych na rozwój rolnictwa regionu kujawsko-pomorskiego na przykładzie PROW
Authors: Biczkowski Mirosław , Jezierska-Thole Aleksandra
Published: November 2023

Analiza wdrażania PROW wykazała, że był to program, z którego beneficjenci chętnie korzystali. Wynika to poniekąd z jego specyfiki, bowiem został on ukierunkowany na wsparcie dużej liczby niewielkich kwotowo inwestycji. Ogólna liczba wniosków przyjętych do realizacji w regionie kujawsko-pomorskim w ramach analizowanych działań wyniosła 29,1 tys., co stanowiło 6,8% ogółu wniosków w skali kraju. Zestawiając liczbę wdrożonych wniosków z liczbą indywidualnych gospodarstw rolnych można stwierdzić, że 38,4% gospodarstw wzięło udział w którymś z działań PROW. Największe zainteresowanie towarzyszyło działaniu ukierunkowanemu na dostosowanie gospodarstw rolnych do standardów UE (45,4% ogółu wniosków). Łączna wielkość środków rozdysponowanych w ramach PROW przekroczyła 713 mln zł (10,7% ogólnej puli środków w kraju), co czyniło z tego programu równoważny instrument wsparcia rolnictwa obok równolegle wdrażanego SPO Rolnictwo. Analiza alokacji środków PROW podkreśliła dominującą rolę działania ukierunkowanego na dostosowanie gospodarstw do standardów UE (61,2% budżetu PROW).
Ekologizacja procesu produkcji wielkopolskich przedsiębiorstw mleczarskich
Authors: Hadryjańska Barbara
Published: November 2023

W pracy przedstawiono działania ekologizacje, jakie są prowadzone w przedsiębiorstwach mleczarskich na terenie Wielkopolski. Badaniom ankietowym poddano 32 jednostki, wśród których występowały przedsiębiorstwa małe, średnie i duże. Respondenci odpowiadali na pytania związane z czynnikami motywującymi do podejmowania działań pro środowiskowych, a także priorytetami, czy też barierami takich działań. Przedsiębiorstwa mleczarskie określały zmiany parametrów środowiskowych oraz zmiany w polityce środowiskowej firmy. W badanych przedsiębiorstwach podejmowane są działania pro środowiskowe, których forma oraz intensywność zależą od wielkości jednostki produkcyjnej W większości badanych przedsiębiorstw poprawie uległy parametry środowiskowe, takie jak waga odpadów w przeliczeniu na produkt gotowy, ilość opakowań odzyskiwanych w stosunku do całkowitej ilości opakowań, wielkość emisji do atmosfery, czy też ilość ścieków powstających w procesie produkcji.
Rola produktów tradycyjnych i regionalnych w podejmowaniu decyzji nabywczych przez konsumentów na rynku dóbr żywnościowych w Polsce
Authors: Grębowiec Mariusz
Published: November 2023

Opracowanie poświęcono cieszącemu się coraz większym zainteresowaniem zagadnieniu, jakim są tradycyjne i regionalne produkty żywnościowe. Opierając się o dostępną literaturę, artykuły z czasopism branżowych oraz informacje zawarte na stronach internetowych zdefiniowano i scharakteryzowano rynek żywności tradycyjnej i regionalnej. Dodatkowo przeprowadzono badania ankietowe, dzięki którym sprawdzono stopień znajomości i rozpoznawalności takich produktów wśród polskich konsumentów oraz ich stosunek do tego typu żywności
Proces integracji europejskiej a napływ bezpośrednich inwestycji zagranicznych do sektora rolno-żywnościowego
Authors: Lizińska Wiesława
Published: November 2023

Celem pracy jest przedstawienie zmian napływu bezpośrednich inwestycji zagranicznych (BIZ) do Polski na tle napływu do krajów Europy Środkowo-Wschodniej w latach 2005-2008 oraz napływu BIZ do polskiego sektora rolno-żywościowego w latach 1996-2008 w kontekście procesu integracji europejskiej. Proces integracji europejskiej jest ważnym czynnikiem decydującym o napływie BIZ do Polski, ale jest on również uzależniony od tendencji ogólnoświatowych. Najwięcej kapitału zagranicznego do sektora produkcji artykułów spożywczych, napojów i wyrobów tytoniowych napłynęło w latach: 1996 i 1998. W przypadku rolnictwa i rybołówstwa największy napływ BIZ odnotowano w 2008 r. (100 mln euro) oraz w 2004 r. (85,5 mln euro). Udział napływu do rolnictwa, rybołówstwa oraz produkcji artykułów spożywczych w ogólnej wartości napływającego kapitału jest niewielki. Napływ kapitału zagranicznego do rolnictwa i przetwórstwa spożywczego miał tendencję wzrostową już przed akcesją (odwrotnie niż napływ kapitału ogółem). W roku akcesji odnotowano wzrost wartości zainwestowanego kapitału zagranicznego ogółem oraz w analizowanych sektorach.
Aktywność samorządów i partycypacja społeczna w kreowaniu warunków sprzyjających rozwojowi lokalnemu
Authors: Pomianek Iwona
Published: November 2023

Celem opracowania jest określenie roli jakości kapitału ludzkiego przedstawicieli lokalnych samorządów w rozwoju społeczno-gospodarczym gmin. Badania empiryczne przeprowadzono w 2008 r. w województwie warmińsko-mazurskim. Dla wszystkich gmin miejsko-wiejskich i wiejskich obliczono syntetyczny wskaźnik poziomu rozwoju społeczno gospodarczego przy zastosowaniu metody wzorca rozwoju Hellwiga, a następnie jednostki zaszeregowano w 3 klasy. Następnie badaniem ankietowym objęto obszar wiejski powiatów ziemskich, w których udział ludności wiejskiej w ludności ogółem (wskaźnik ruralizacji) przekraczał 50%. Badania wykazały, iż jakość kapitału ludzkiego przedstawicieli samorządów gminnych (mierzonego za pomocą posiadanego wykształcenia i reprezentowanej grupy zawodowej), a także aktywność obywatelska (wyrażona frekwencją w wyborach) oraz gospodarcza (mierzona wskaźnikami przedsiębiorczości) mieszkańców badanych gmin są dodatnio powiązane z poziomem rozwoju społeczno-gospodarczego. W gminach, gdzie strategie rozwoju przygotowywano przy współudziale lokalnych liderów, odnotowywano większe sukcesy w ich realizacji.
Wpływ zatrudnienia na rentowność i bezpieczeństwo finansowe wybranych spółdzielni mleczarskich w Polsce
Authors: Zuba Maria
Published: November 2023

Badaniami objęto 41 spółdzielni mleczarskich w okresie czterech lat (2002-2005). Celem pracy jest określenie wpływu zatrudnienia na rentowność i bezpieczeństwo finansowe spółdzielni mleczarskich. Badania wykazały, że zatrudnienie miało pozytywny wpływ głównie na poziomy rentowności sprzedaży, majątku, kapitału własnego i zatrudnienia.
Hipoteza efektywności rynku – weryfikacja dla indeksu WIG- Spożywczy
Authors: Waszkowski Adam
Published: November 2023

W pracy poddano weryfikacji hipotezę o słabej efektywności informacyjnej rynku finansowego. Badania przeprowadzono dla indeksu WIG-Spożywczy. Wykorzystano w tym celu test Walda-Wolfowitza, test współczynnika autokorelacji Quenouille’a, łączną statystykę Ljunga-Boxa oraz testy efektów stycznia oraz poniedziałku. Analizę przeprowadzono w oparciu o dzienne logarytmiczne stopy zwrotu dla okresu od 31.12.1998 do 05.05.2011 dla wyznaczonych 11 podprób.
Fragments of holy warrior cycles in the Parekklesia of the Mileseva Monastery
Authors: Filipovic Ivana , Stevanovic Bojana
Published: November 2023

King Vladislav?s foundation, the Mileseva Monastery with its Church of the
Ascension, was built in the thirteenth century near Prijepolje. The
architecture and wall paintings of the church have already been exhaustively
researched. However, the fragments of frescoes in the katholikon?s side
parekklesia have remained unexplored, and the remnants of the scenes
unidentified. Both lateral structures are dedicated to warrior saints - St.
George and St. Demetrios. The imagery of these parekklesia included some
images from the vitae of these megalomartyrs. The paper describes and
identifies their remnants, comparing them with similar representations in
the programs of other foundations.
From an imperial stemma to a laurel wreath. Images of rulers on prince Lazar’s coinage
Authors: Odak Marina
Published: November 2023

The paper deals with the representations of rulers on the coinage of Prince
Lazar while tracing the iconographic and insignological changes in the
depiction of the prince, which reflected Lazar?s political program in
different phases of his reign. Modeling his first representations on the
dinars he minted on the coinage images of the emperors Dusan and Uros,
shaped on their money according to the formulas of Byzantine imperial
images, after consolidating his power, Lazar gradually left the framework of
the Byzantine ruler iconography and entered the sphere of the western
monarchical image, culminating in the representation of the prince depicted
in a profile bust with a laurel wreath, created under the influence of
Hungarian coinage.
Nature-based Solutions for corporate climate targets: views regarding the corporate use of Nature-based Solutions to meet net-zero goals
Authors: Martinez G. , Drion B. , Gladstone J. , Vidal A.
Published: November 2023

Nature-based Solutions (NbS) are activities undertaken to protect, sustainably manage and restore natural and modified ecosystems to simultaneously benefit people and nature. NbS are critical to addressing challenges like climate change, food security, water security, disaster risk, human health, and social and economic development. NbS balances conservation with sustainable development and showcases how nature can benefit societal and human well-being. Therefore, NbS are critical to achieving a low-carbon future while facilitating climate change adaptation and supporting other critical ecosystem functions. This publication outlines the available pathways to include NbS in corporate climate strategies consistent with the NbS definition, principles and Global Standard for NbS™. When correctly implemented, NbS can contribute to climate mitigation and adaptation while offering important benefits for biodiversity and human well-being.
Perceived Organizational Inclusion: Evidence from Neurodivergent Accountants in the U.S.
Authors: Jiles Loreal , Duong Qi , Venkatesh Roopa
Published: November 2023

SYNOPSIS

To address talent attraction and retention challenges with respect to diverse talent in the accounting profession, this study examines the intersection of neurodiversity and the accounting employment experience. Through interviews and online questionnaires of neurodivergent accountants in the U.S., we found a general lack of perceived organizational inclusion among neurodivergent accountants in our study, evidence supporting the existence of a positive impact of perceived organizational inclusion on individuals’ perceptions of their job performance, and key antecedents to perceived organizational inclusion. We report the lived experiences of neurodivergent accountants by amplifying their voices through presentation of oral histories and 37 actionable practices informing future strategies for organizations and leaders in practice.

JEL Classifications: M14.
The Decision-Usefulness of ASC 606 Revenue Disaggregation
Authors: Hinson Lisa A. , Pündrich Gabriel P. , Zakota Mark
Published: November 2023

The disclosure requirements of ASC 606 significantly expanded the volume and granularity of revenue information. However, because of the significant judgment associated with the standard, it is unclear whether the new disclosures increased the decision-usefulness of financial reports. To shed light on this question, we investigate the revenue disaggregation requirements of ASC 606. These requirements had significant disclosure consequences, illustrated by an over two-fold increase in the median number of revenue items in disaggregating firms’ reports. Consistent with enhanced decision-usefulness, we find higher (lower) analyst sales forecast accuracy (dispersion) for disaggregating firms. These benefits are primarily present when disaggregation is accompanied by detailed qualitative disclosures, when disaggregated revenues are comparable, and when the granularity of segment information is low. Our study contributes to research evaluating ASC 606 and offers valuable insights to standard-setters currently considering broader disaggregation of income statement items (Financial Accounting Standards Board (FASB) 2022).

Data Availability: Data are available from the sources identified in the paper.

JEL Classifications: G24; G30; G34.
Mechanical Regulation of Retinal Vascular Inflammation and Degeneration in Diabetes
Authors: Chandrakumar Sathishkumar , Santiago Tierno Irene , Agarwal Mahesh , Lessieur Emma M. , Du Yunpeng , Tang Jie , Kiser Jianying , Yang Xiao , Rodriguez Anthony , Kern Timothy S. , Ghosh Kaustabh
Published: November 2023

Vascular inflammation is known to cause degeneration of retinal capillaries in early diabetic retinopathy (DR), a major microvascular complication of diabetes. Past studies investigating these diabetes-induced retinal vascular abnormalities have focused primarily on the role of molecular or biochemical cues. Here we show that retinal vascular inflammation and degeneration in diabetes are also mechanically regulated by the increase in retinal vascular stiffness caused by overexpression of the collagen–cross-linking enzyme lysyl oxidase (LOX). Treatment of diabetic mice with LOX inhibitor β-aminopropionitrile (BAPN) prevented the increase in retinal capillary stiffness, vascular intracellular adhesion molecule-1 overexpression, and leukostasis. Consistent with these anti-inflammatory effects, BAPN treatment of diabetic mice blocked the upregulation of proapoptotic caspase-3 in retinal vessels, which concomitantly reduced retinal capillary degeneration, pericyte ghost formation, and the diabetes-induced loss of contrast sensitivity in these mice. Finally, our in vitro studies indicate that retinal capillary stiffening is sufficient to increase the adhesiveness and neutrophil elastase-induced death of retinal endothelial cells. By uncovering a link between LOX-dependent capillary stiffening and the development of retinal vascular and functional defects in diabetes, these findings offer a new insight into DR pathogenesis that has important translational potential.

Article Highlights
Euglycemic Ketoacidosis in Two Patients Without Diabetes After Introduction of Sodium–Glucose Cotransporter 2 Inhibitor for Heart Failure With Reduced Ejection Fraction
Authors: Umapathysivam Mahesh M. , Gunton James , Stranks Steve N. , Jesudason David
Published: November 2023

OBJECTIVE

Ketoacidosis induced by sodium–glucose cotransporter 2 inhibitor (SGLT2i) treatment has been consistently observed in clinical practice in patients with type 2 diabetes despite minimal indication from the landmark cardiovascular outcome trials. It has been postulated that individuals without diabetes will not develop this complication due to an adequate insulin secretory capacity, which will protect against significant ketone formation. Cardiovascular outcome trials examining SGLT2i use in individuals with heart failure but not diabetes have not reported ketoacidosis.

RESEARCH DESIGN AND METHODS

We describe the first two case reports of severe nondiabetic ketoacidosis after initiation of an SGLT2i for the treatment of heart failure with reduced ejection fraction, and we describe the management strategies employed and implication for the pathophysiology of SGLT2i-associated ketoacidosis.

RESULTS

Each individual presented with ketoacidosis triggered by reduced oral nutrition intake. For both individuals, ketoacidosis resolved with intravenous glucose administration, encouragement of consumption of oral glucose-containing fluid, and minimal insulin administration.

CONCLUSIONS

These two cases demonstrate that SGLT2i-associated ketoacidosis is possible in individuals without diabetes.