bluuebunny/crossref_metadata_2025 huggingface dataset:
KAJIAN PEMANFAATAN LIMBAH DAUN KAYU PUTIH UNTUK MEMPERBAIKI FAKTOR PEMBATAS KESUBURAN TANAH
Authors: Ertanto M. Ahdan Abror , Syekhfani S , Abdillah Erlangga
Published: June 2022

The utilization of eucalyptus leaf waste in the processing unit of the eucalyptus oil factory has not been carried out optimally and has great potential as raw material for making organic fertilizer in the form of compost. This study aimed to study the potential use of eucalyptus leaf compost to improve soil fertility limiting factors in Jati Plus plantations. This research was conducted at the Department of Research and Innovation of the Perhutani Forestry Institute, Cepu, Central Java, and in the chemical laboratory of the Department of Soil, FPUB. This study used a completely randomized design consisting of four treatments and three replications. The results showed that eucalyptus leaf waste could be composted with organic carbon content, total nitrogen, total P2O5, total K2O, high organic matter content, high cation exchange capacity, and neutral pH. Perhutani's Teak Plus Plantation has fertility limiting factors on the ustic soil moisture regime, alkaline soil reaction, and clay texture. Eucalyptus leaf waste compost can be used as organic material for the strategic direction of soil management in several Jati Plus Perhutani plantation areas.
ANALISIS INDEKS KEKERINGAN METODE STANDARDIZED PRECIPITATION INDEX (SPI) DAN PENGARUHNYA TERHADAP PRODUKTIVITAS PADI DAN JAGUNG
Authors: Masruroh Dewi , Bowo Cahyoadi
Published: June 2022

Drought is one of the most significant impacts of the climate on agriculture, especially food crops. Standardized Precipitation Index (SPI) is an Index for droughts. The research objective was to study the relationship of SPI values to the productivity of rice and corn crops in the Situbondo district. The result showed that the value of the SPI time scale at three months is the most appropriate for the observed productivity of rice and corn. The SPI value significantly correlated with the productivity of rice plants in the Jatibanteng and Arjasa districts but did not significantly affect the productivity of corn in the Mlandingan and Situbondo districts. Furthermore, the El-Nino phenomenon reduced the rice productivity up to 3.9% and the corn productivity up to 48.1%. The La-Nina phenomenon reduced rice productivity up to 26.0% but increased the productivity of corn up to 81.7%.
Classification of Malaysian Architecture Revisited
Authors: Wahid Julaihi , Abdullah Azli Bin , Salleh Basseem , Arar Mohd
Published: June 2022

This paper attempts to portray the classification of Malaysian architecture according to the trends and changes along with the advancement of the economy, technology and growth of architecture schools in Malaysia. The faces of Malaysian architecture are very much influenced by graduates in architecture returning from overseas and the establishment of the Malaysian Institute of Architects. Malaysia is blessed with natural beauty and resources that enable it to be independent. The hot-wet equatorial climate of Malaysia and its high humidity together with the abundance of timber and other cheap building materials enable builders and architects alike to experiment with the built forms. The traditional and vernacular architecture that has been crystallized in the colonial style by the pioneer British architects who designed the government quarters and other government buildings in Malaysia revealed the attention towards the climatic factors and the style that later developed into modern and post-modern style that appear in the residential design of the Malaysian landscape today. This paper employs an exploratory technique from earlier writings and longitudinal historical evidences of Malaysian architecture, visual surveys from the digital media and verbal comments from the practising Architects interviewed. The finding shows that the Malaysian Architecture can be classified according to era, style and contemporary trends influenced by the changes in the world.
Kualitas Visual Fasad Bangunan Bersejarah Jalan Hassanudin Kota Batu
Authors: Nugroho Rahadian , Ernawati Jenny , Triwinarto Joko
Published: June 2022

Relics of buildings with Dutch colonial architecture to this day can still be found in several road corridors, especially in Pesanggrahan Village, one of which is Jalan Hassanudin, Batu City. This study serves to measure and measure the community towards building units in forming the image of the area on the corridor of Jalan Hassanudin. This research uses the imageability factor which is used to see the character of the area consisting of impressions, past memories, unforgettable memories, uniqueness, attractiveness, clarity, enjoyment and uniqueness. The measuring instrument used is the semantic differential scale of previous research references. The results of the research regarding impressions are the most dominant variable based on people's impressions. impressiveness, uniqueeness, atractiveness, clarity, pleasantness, distinctiveness, recognizableness are significant variables to the image of the historical area in the corridor of Jalan Hassanudin. Meanwhile, variables such as unforgettable memory and remembrance of the past are variables that have a sig value. > 0.05 so that it does not affect the image of the area.
Editor-in-Chief address
Authors: Kosarev A. B.
Published: June 2022

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Doing Away With Borders: Jornal de Borda Goes Beyond the Frontiers of Art
Authors: Grigolin Fernanda , Wabi-Sabi Mirna
Published: June 2022

Artists' publications are often used in contemporary art studies in discussions about the printed page. However, these publications go beyond their nomenclatures and place in art institutions. The boundaries of visual arts are increasingly blurred, and discussions of works of art become more potent when viewed within the broader spectrum of visual culture. Aesthetics have the power to produce knowledge and establish relations with ways of living and being in the world and throughout history. Publications, as such, are social places that can mediate these relationships between people, especially when it involves issues like feminism, capitalism, and decoloniality. The Jornal de Borda — an anarchist visual culture newspaper circulated in Latin America in Portuguese and Spanish between 2015 and 2021 — is an example of artistic expression through printing. It strategizes the name of dissenting bodies — referred to as “corpas” — in the context of art within visual culture; it establishes relations between these bodies and anarchism within the Latin American context; and the aesthetic relates directly to other newspapers from the last century, such as A Plebe, honoring history as it makes history.
Lekkers in de Boekentoren
Authors: Devriese Luc , Brysse Adrien
Published: June 2022

Ferdinand Vanderhaeghen (1830-1913), de onvermoeibare bibliothecaris van de Gentse Universiteit, achtte niets te min, als het maar op papier stond. Hij verzamelde zelf allerlei etiketten, vlugschriften, reclames, etc. en hij spoorde vrienden en kennissen aan hetzelfde te doen. Daaraan dankt de Gentse universiteitsbibliotheek zijn unieke collectie ‘Vliegende Bladen’.
Beddenzakken voor Baafse monniken.
Authors: Hanson Marc
Published: June 2022

Matrassen zoals wij die kennen, bestonden in de middeleeuwen nog lang niet. Stro en kaf waren het meest voorkomende vulsel van de tijken (ruw linnen) beddenzakken, maar dat stond onderaan op de lijst van het comfortniveau.
Een door godsdiensttwisten verdeelde familie De familie Schoutheet in het Gentse (1577-1578)
Authors: Mattens Danny
Published: June 2022

De naam Schoutheet betekent in het Nederlands schout. Dat is iemand die een oordeel, een schuld uitspreekt. In de geschiedenis van het Gentse blijven herinneringen aan die familie bewaard, met name op het Westveld (Sint-Amandsberg). Daar verscheen de naam Schoutheet (Schautheet, Schouteet, Schoutheete) in de achttiende eeuw.
Minder bekende Gentse fotografen. Edouard Renoz (Parijs 1830 – Gent 1862). Beloftevol, maar veel te vroeg gestorven
Authors: Verhoosele Françoise
Published: June 2022

In deze kleine reeks over Gentse fotografen worden enkele nobele onbekenden eventjes in het licht van de schijnwerpers gebracht.
Charles van Rysselberghe bouwt in Sint-Pieters-Buiten. Deel 3. Eigendommen en huizen.
Authors: Steeman Jan
Published: June 2022

Charles Van Rysselberghe, in middels stadsarchitect van Gent, bouwt in de Sint-Pietersstationsbuurt een vastgoedpatrimonium op.
Geen (pseudo)metselaarshuis aan de Graslei, maar ‘de Ingel’
Authors: Redactie GT
Published: June 2022

Toeristisch Gent kan bogen op een wel heel bijzondere eigenaardigheid: twee schitterende, min of meer gelijkaardige gevels van twee gebouwen die beiden ‘Metselaarshuis’ genoemd werden: een ‘echt’ en een ‘vals’.
Veldwachters in Ledeberg (1795-1874).
Authors: Van Hecke Achiel
Published: June 2022

Het ontstaan van de Belgische politiediensten is te situeren in de periode waarin België bij Frankrijk geannexeerd was (1795-1814). Zo werd de door de Franse Nationale Vergadering gestemde wet op de politiediensten
van 28 september 1791 van kracht in wat nu België is. In landelijke gemeenten werden veldwachters aangesteld.
Middeleeuws begraven door Schokkebroers en Matewijven in Gent. Deel 2. In ‘gariten’ en een ‘celle’ op de Sint-Michielsvest
Authors: Devriese Luc
Published: June 2022

In dit tweede deel bekijken we de nogal ongewone middeleeuwse woonvorm van de Gentse begraafbroeders, de schokkebroers, alias cellebroeders. In Gent huisden ze op de oude stadsvesten bij de Poel. Een uniek inzicht in de primitieve woonvorm, m.n. gariten: plekken op de vestwallen waar de stadsverdedigers konden schuilen.
Lezers aan het woord
Authors: Redactie GT
Published: June 2022

Palfijn. Facteursbeeld Germain Janssens. Mannekepis in het stadhuis. Volkscafés. Spoorwegbrug Kasteellaan Dok-Zuid.
Marie Brouillard, alias tante Nitte, onterecht vergeten
Authors: Gyselinck Sonja
Published: June 2022

Het is weinig of niet geweten dat Marie Brouillard een zeer groot aandeel in de populariteit van haar man Romain Deconinck, van wie zij de tweede vrouw was. Ze was de auteur van muziek en tekst van zijn bekendste succesliedjes en verzorgde kostuums en choreografie van zijn revues. Ze leeft voort in de naam van het nog steeds goed draaiende café Marimain naast de Minard, maar is verder zo goed als onbekend.
t Fortje aan de Blaisantvest. Cité Voortman, nu kerkje
Authors: Devriese Luc
Published: June 2022

Het beluik ‘t Fortje aan de Blaisantvest, gebouwd in de beginjaren van de 19de eeuw op een gewezen bastion (bolwerk), bleef tot in de tweede helft van vorige eeuw bewoond. Het was toen een van de oudste Gentse cités (cité ouvrière: arbeidersbeluik). Het wooncomplex was echter al lang gedegradeerd tot een van de slechtst befaamde. Dit artikeltje belicht de geschiedenis van de cité, vooral aan de hand van het overvloedig beschikbare beeldmateriaal, aangevuld met de in briefvorm bewaarde bitse disputen eind jaren 1800 gevoerd tussen de Stad en eigenaar Jules Voortman.
Het oorlogsverleden (W.O. II) van het Citadelpark en de Leopold - kazerne
Authors: Antheunis Georges
Published: June 2022

Aanvullend bij het artikel van Ghislain (Guy) Mineur, wordt een korte schets gegeven van de bouw en de functie van de schuilplaatsen die kort voor en tijdens de tweede wereldoorlog gebouwd werden in en bij het Citadelpark. Daarnaast worden de opeenvolgende Duitse bezettingstroepen in de Leopoldkazerne opgesomd en geïllustreerd.
Judo, biljarten, dammen en marktfolklore in de Kammerstraat (begin jaren 1960).
Authors: Tombeur Franklin
Published: June 2022

Wat valt er nog meer te vertellen over het authentieke café chantant ‘Het Wit Paard‘ ingericht op het gelijkvloers van een nog bestaand trapgevelhuis in de Kammerstraat bij de Vrijdagmarkt.
Lezers aan het woord
Authors: Redactie GT
Published: June 2022

Slag om Engeland merkbaar tot in Gent. Betoging in militair uniform WO II. Kruitlepel. Niet Troch maar Francis Toch. Zwaanridders en Heren van Kleef en Ravenstein. De vijftiende-eeuwse Dulle Griet/Groot Kanon-bombarde.
Ectopic thymic carcinoma in the nasopharynx of a Golden Retriever
Authors: Willemse T.W.J , Scase T. , Marti J. , Di Bella A.
Published: June 2022

An eleven-year-old, male, neutered Golden Retriever was referred for a chronic history of stertorous breathing, inspiratory stridor and mucopurulent discharge from the left nostril. A computed tomographic (CT) scan of the head, neck and thorax revealed a nasopharyngeal mass causing bone lysis of the hard palate. There were no signs of local or distant metastatic disease. Nasopharyngoscopy confirmed a large mass, occluding the entire nasopharynx. Histopathologi cal analysis of the biopsies was indicative of a chronic inflammatory polyp. The mass was surgi cally removed through a ventral approach to the nasopharynx. Histopathological examination of the mass identified it as a thymic carcinoma arising from ectopic thymic tissue. The dog recov ered well but died of unknown causes one year later.
Ultrasonographic and radiographic findings of the kidneys in six dogs and one cat with ethylene glycol intoxication
Authors: Eberlé O. , Pouzot-Nevoret C. , Barthélemy A. , Drumond B. , Harel M. , Belluco S. , Ségard-Weisse E.
Published: June 2022

Antifreeze is the most common source of ethylene glycol poisoning in small animals, caus[1]ing rapid development of acute kidney injury. Ethylene glycol intoxication has been described in the past. However, the evolution of ultrasound devices, and in particular the use of linear probes, allow a more precise evaluation of changes in the echostructure of the kidneys. In this study, the renal ultrasonographic findings were evaluated in six dogs and one cat with ethylene glycol intoxication; particularly, echogenicity changes within the medulla, and the radiographic features of the kidneys in two dogs are described. Severe cortical hyperechogenicity was present in all dogs and was associated with acoustic shadowing in one dog. Different forms of medullary echogenicity were identified with the medullary rim sign being the most common finding. In two dogs, abdominal radiographs showed a diffuse homogeneous increased opacity of both kidneys. However, none of these changes are pathognomonic for ethylene glycol poisoning. In the cat, cortical echogenicity was normal upon admission and evolved into mild hyperechogenicity. The cat did not present medullary rim sign but showed an association of severe hyperechoic outer medulla and moderate medullary band sign.
PECULIAR FEATURES OF METABOLIC AND HORMONAL INDEXES IN PATIENTS WITH ABDOMINAL OBESITY
Authors: Каshperska V. Ya.
Published: June 2022

Results of examination of 73 patients with the abdominal type of obesity allowed one to diagnose dyslipidemia IIb, in 31 % of cases — carbohydrate metabolic disturbance, in 88 % — hyperinsulinemia. Individuals with abdominal obesity have a decrease in the testosterone level as a negative factor of growth in mass of the abdominal fatty tissue, development and progress of insulin resistance, increased serum atherogeny. Reversed dependence of the abdominal fatty tissue and the blood testosterone level was established in male patients.
APPLICATION OF INSULIN DRUGS HENSULIN R, HENSULIN H AND HENSULIN M30 FOR PATIENTS WITH DIABETES MELLITUS
Authors: Kravchun N. A. , Kazakov Alexandr , Oleinikova S. P. , Zemlyanitsyna O. V. , Romanova I. P.
Published: June 2022

The efficacy of insulin drugs — Hensulin R, Hensulin H and Hensulin M30 has been studied in patients with types 1 and 2 diabetes mellitus. The insulins under test were shown to have an effective hypoglycemic action. No negative influence on other metabolic indices of diabetic patients was observed.
STATUS OF INTRARENAL HEMODYNAMICS AND TUBULAR KIDNEY APPARATUS IN NORMOALBUMINURIC CHILDREN WITH 1 TYPE DIABETES MELLITUS
Authors: Makeyeva N. I.
Published: June 2022

It was shown the decreased or absent renal functional reserve in diabetic normoalbuminuric patients with a normal level of glomerular rate filtration indicates the diabetic damage of kidney vessel apparatus. The increased β2-microglobulin excretion in children with 1 type diabetes mellitus is specified as a tubular dysfunction marker and ground for early diagnostics of diabetic nephropathy.
IMMUNOHISTOCHEMICAL PECULIAR FEATURES OF TESTES IN FETUSES AND NEWBORNS FROM MOTHERS WITH PRE-ECLAMPSIA
Authors: Potapov S. N. , Yakovtsova A. F.
Published: June 2022

The pre-eclampsia influence on a structure of the testes in fetuses and newborns was studied using immunohistochemical techniques. Revealed changes were associated with a degree of apoptosis and proliferation, a condition of the blood-testis barrier and processes of angiogenesis. The degree of the changes was directly proportional to pre-eclampsia severity.
PHYTOESTROGENS EFFECT ON SEXUAL HORMONES LEVEL AND FERTILITY OF RATS
Authors: Somova E. V. , Gladkova A. I. , Karpenko N. A. , Koreneva Yevheniia , Chistyakova Elina , Selyukova Nataliia
Published: June 2022

The influence of 30-day application of phytoestrogens compound to postpubertal male and female rats on the level of sexual hormones, gametes maturation and fertilization capacity was experimentally studied. Long-term phytoestrogenes supplies into animal’s organism bring out substantial changes in the level of sexual hormones. In females different estradiol contents are levelled at the estrus-diestrus stages that is typical for intact females. In males there was a considerable increase of estradiol, in a lesser degree — testosterone. Hence, the testosterone-esrtadiol ratio is altered. Morphological structural changes in male and female gametes, decreased spermatozoa motility, impaired embryonic implantation, a high rate of embryonic mortality are observed.
EFFICIENCY OF INSULINOTHERAPY OF DIABETES MELLITUS TYPE 1 IN CHILDREN AND ADOLESCENTS
Authors: Budreiko O. A.
Published: June 2022

Analysis of the treatment of type-1 diabetes in children and adolescents in recent years has shown a significant increase in using of insulin analogues. Improvement in the compensation of carbohydrate metabolism and state of microcirculation on the background of the use of insulin analogues when compared with other insulin drugs is shown. The importance of maintaining stable blood glucose levels at night to prevent the development of microcirculatory disorders, which is ensured, primarily by the drugs of non-peak prolonged insulin action was proved.
INSULIN RESISTANCE INCIDENCE IN CHILDREN AND ADOLESCENTS WITH OBESITY
Authors: Budreiko O. A. , Nikitin L. D. , Chumak S. O. , Filipova N. V. , Yudchenko O. I.
Published: June 2022

Examination of 186 children and adolescents with obesity has shown that insulin resistance according to HOMA index is revealed significantly more often (44,3 %) than carbohydrate metabolism disorders according to WHO criteria (5,9 %). Insulin resistance incidence in boys in early and late puberty as compared with prepuberty, increased 4 times. In girls it was registered only in puberty and was less frequent than in boys. It has been established that in children and adolescents with obesity insulin resistance incidence depends mostly not on the type of obesity (hypothalamic or exogenous constitutional) but on the degree of excess body weight.
EXPERIENCE OF THE THERAPY OF HYPOANDROGEN MALE INFERTILITY WITH TAMOXIFEN — AEVIT COMBINATION
Authors: Kozhemyaka V. A. , Bondarenko Volodymyr , Minuchin Andriy
Published: June 2022

Studies into peculiar changes of spermatogram parameters, fructose content in ejuaculate and hormonal levels of hypophysic-gonadal system using the therapy of idiopathic pathospermias in hypoandrogenized males treated with Tamoxifen-Aevit combination have been performed. The applied therapy led to a profound improvement of spermatogram parameters, testosterone secretion stimulation, increased fructose concentration in ejaculate. Tamoxifen combined with Aevit had a more substantial influence upon normalization of all spermatogram parameters of infertile males when prior to their treatment the testosterone-luteinizing hormone ratio exceeded 2,0.
PECULIAR VARIATIONS OF THE INCRETORAL AND SPERMATOGENIC TESTICLE FUNCTION IN HYPOTHYROIDISM-AFFECTED MEN TREATED WITH L-THYROXIN
Authors: Bondarenko Volodymyr , Spivak Zh. S. , Zubko M. I. , Miroshnichenko A. V.
Published: June 2022

The present study has been aimed at determining levels of thyroid-stimulating hormone, thyroxin, free and total testosterone in blood, spermatogram parameters in 20 reproductive men afflicted with primary hypothyroidism prior, following 1 and 3 months of L-thyroxin treatment. Upon completion of 3-month therapy average testosterone values were found to increase profoundly in blood. The spermatozoon amount in 1ml of ejaculate, the percentage of their active and viable forms raised considerably either. It has been revealed that these positive changes in testicles of patients with hypothyroidism take place with regard to the thyroid status compensation.
THERAPEUTIC CORRECTION OF AUTOIMMUNE THYROIDITIS FROM HYPOTHY HYPERTHUNCTION OF THE THYROID GLAND
Authors: Kravchun N. O. , Kozakov Alexandr , Chernyavska Irina
Published: June 2022

The influence of the herbal drug "Zobofit" on the functional activity, structure, including focal changes, thyroid gland, as well as

indicators of autoimmunity in patients with autoimmune thyroiditis.
VITEFFECT OF NOOTROPIC AND NEUROPROTECTOR PRODUCTS PROPERTIES OF ENERGY METABOLISM PROCESSES AND MANIFESTATIONS OF MITOCHONDRIAL DYSFUNCTION IN THE NEURONS OF THE MAIN BRAIN OF RATS WITH ALOXAN DIAMIN D STATUS IN ADOLSECENTS WITH TYPE 1 DIABETES MELLITUS
Authors: Zhylyuk V. I. , Mamchur V. Y. , Pavlov S. V. , Bukhtiyarova N. V.
Published: June 2022

In experimental studies in rats with chronic alloxan-induced hyperglycemia, it was found that the use of piracetam for 20 days,

pramiracetam and ginkgo biloba extract to varying degrees help to reduce the effects of mitochondrial dysfunction and energy deficiency in brain neurons. The basis of these mechanisms is the prevention of mitochondrial opening

cyclosporine-A-sensitive pores, reduction of mitochondrial transmembrane potential and increase of synthesis of macroergic phosphates. The most important

the effect under these conditions has pramiracetam.
HISTOFUNCTIONAL FEATURES OF VISCERAL ADHESIVE TISSUE THE DESCENDANTS OF GESTALLY STRESSED MOTHERS
Authors: Sergienko L. Yu. , Perets O. V. , Kartavtseva O. V. , Cherevko G. M. , Tolmachova L. M. , Bondarenko T. V.
Published: June 2022

A comparative study of the histostructure of adipose tissue in females was performed rats - offspring of intact and gestational stressed mothers in the basal state and after the action of stress factors. It was found that the stress of mature offspring

leads to the formation of a hypertrophic type of obesity in intact animals and provokes adipocyte hyperplasia and adipose tissue inflammation in rats stressed during the antenatal period.
ADIPOCYTOKINES IN DEVELOPMENT INSULIN RESISTANCE IN OBESITY
Authors: Yarmysh N. V. , Kravchenko N. A. , Voitenko E. I.
Published: June 2022

Adipose tissue is key regulator of energy balance and plays an active role in the accumulation of lipids,

as well as the synthesis and secretion of a wide range of adipokines that could potentially be involved in pathogenetic events associated with obesity
THE PROTECTIVE EFFECT OF QUERCETIN ON THE DEVELOPMENT OF METABOLIC SYNDROME IN THE OVARIECTOMIZED RATS FED WITH THE HIGH-FAT DIET
Authors: Borikov Oleksii
Published: June 2022

The aim of the study was to investigate the impact of quercetin on the metabolic manifestations of insulin resistance syndrome induced by high-fat diet in rats under estrogen deficiency. It was revealed that treatment with quercetin ameliorated insulin resistance, decreased visceral fat mass and lipid peroxidation in serum and heart, increased endogen nitric oxide production and decreased ADP-induced platelet aggregation in the ovariectomized rats fed with the high-fat diet. These results show that the quercetin may be used for treatment of the cardio-vascular diseases in postmenopausalwomen.
MORPHOLOGICAL AND BIOCHEMICAL INDEXES OF SEMEN IN MALE PATIENTS WITH DIABETES MELLITUS
Authors: Luchytskiy E. V. , Luchytskiy V. E. , Skladannaya I. I. , Zubkova G. A.
Published: June 2022

Estimation of the sperm parameters and measurement of sex hormones levels were performed in 35 men with diabetes mellitus. The data obtained revealed the negative changes of morphological and biochemical parameters in sperm of males with diabetes compared with the control group, and more significant changes were observed in patients with type 2 diabetes. The changes revealed, except to reduce % of active motility spermatozoa, were within the normal range recommended by WHO.
THE IMPACT OF ESTROGEN DEFICIENCY AND METABOLIC SYNDROME ON THE FUNCTIONAL STATE OF RATS CARDIOVASCULAR SYSTEM
Authors: Ivanova Olha
Published: June 2022

The functional state of cardiovascular system was investigated in ovariectomized rats with metabolic syndrome induced by chronic supplementation with high fructose diet. It was established, that only estrogen deficiency does not disturb the heart rhythm, but leads to prolongation systolic interval, shortening of diastolic interval and duration of P wave. The increased heart rates, systolic index and deformed T wave were observed at the electrocardiogram of rats with estrogen deficiency and metabolic syndrome. Thus, the metabolic syndrome intensified the functional disturbances induced by estrogen deficiency, inducing sinus tachycardia, ischemic heart diseases and diffuse changes of a myocardium.
CONSEQUENCES OF STRESS DURING SUCKLING FOR REPRODUCTIVE FUNCTION OF ADULT FEMALE RATS
Authors: Chistyakova Elina , Karpenko N. O. , Somova O. V.
Published: June 2022

For the study of consequences of stress in a critical period of the physiological suckling the reproductive function of adult female rats exposed to mother separation stress from 3rd till 15thday has been examined. It was found that such conditions led to the change of hormonal profile in the different stages of estrus cycle (higher concentration of testosterone, lower progesterone content in diestrus and flattening of estradiol peak in proestrus), that resulted into the prolongation of estrus cycle in the main over the diestrus phase. The body mass decrease, ovaries mass increase and adrenal mass diminishing at pregnant females, increase of intrauterine losses and inhibition of male fetus embryonal development, specify about production of poor quality oocite and disturbances of pregnancy maintenance at stressed rats.
THE CHARACTERISTIC OF THE EMOTIONAL STATE OF RATS WHOSE MOTHERS WERE AFFECTED BY ESTROGENS OF DIFFERENT NATURE DURING LACTATION PERIOD
Authors: Smolenko Natalia , Karpenko N. A.
Published: June 2022

Suckling female rats had taken a 17β-estradiol or phytoestrogens from 3 till 21 day of lactation. The emotional state of their adult progeny has been investigated in the «elevated plus maze» test and the test «pick up of rats by the tail». The delayed consequences of estrogens intake during critical period of ontogenesis have caused the high level of animals’ anxiety. This effect was considerably intense on male rats while females were more resistant. The 17β-estradiol has a more significant influence then phytoestrogens on formation of the behaviour pattern.
Social activity in shaping the participatory budget
Authors: Dąbrowska Małgorzata
Published: June 2022

In civil society, self-government as a form of social organisation occupies one of the central positions. The condition for the implementation of the development mission of local government is the participation of citizens and their co-responsibility for the shape of local social life. Recently, the participatory budget has become one of the most popular forms of participation. Its aim is to directly involve residents in the decision-making process regarding the choice of the scope of public tasks within the designated pool of funds and to take over part of the responsibility. The aim of the presented analysis is to show the dynamics of citizen involvement in consultations on spending part of the city budget on local tasks falling within the competence of local government – The civic budget. The adopted research hypothesis assumes that the participatory budget is the most popular form of consultation because in its formula it gives residents a sense of agency and subjectivity in expressing one’s opinions and preferences and also gives tangible results of social engagement visible in the short term. The empirical basis for the analysis are reports on the implementation of the participatory budget of the city of Radom from the beginning of its creation, and literature on the subject. A participatory budget is an excellent tool for education about self-government – it is an element of a specific philosophy of functioning of self-government – as a community of authorities and residents of a given territorial unit, cooperating for its development. The example of the city of Radom indicates that the participatory budget supports, complements, and often replaces or increases the efficiency of public administration. The analyses carried out can be an indication when improving the implementation of the budget of Mazovia.
TÜRKÇE DİLİNDE YAZILAN BİLİMSEL METİNLERİN DERİN ÖĞRENME TEKNİĞİ UYGULANARAK ÇOKLU SINIFLANDIRILMASI
Authors: ÖZKAN Mustafa , KAR Görkem
Published: June 2022

Ekim 2018 yılında Google tarafından geliştirilen BERT derin öğrenme tekniği, makine öğrenimi ve doğal dil işleme dünyasında çok popüler oldu. Transformatörlerin Çift Yönlü Kodlayıcı Gösterimleri anlamına gelen BERT, yapay zeka ve makine öğrenimi teknolojilerini bir arada kullanan bir doğal dil işleme tekniği olarak açıklanabilir. Günümüzde, gözetimli öğrenme metodolojisinin bir parçası olan sınıflandırma problemleriyle çokça karşılaşılmaktadır. Sınıflandırmanın temeli eğitilen bir makinenin yeni gelen bir veri hakkında tahminleme yapabilmesine ve sınıflandırabilmesine dayanır. Buradaki amaç bir veri kümesi üzerinde tanımlı olan sınıflar arasında veriyi dağıtabilmektir. Türkçe'nin morfolojisinin zengin ama karmaşık olması, sondan eklemeli bir dil olması ve dil bilgisinden kaynaklanan zorluklar çoklu sınıflandırma problemlerinin çözümünde başlıca sorun teşkil etmekte iken BERT derin öğrenme tekniği ile bu sorun daha kolay çözülebilir hale gelmiştir. Bu çalışmada, son 10 yıl içinde Türkçe dili ile yazılmış akademik araştırma ve bilimsel çalışmalar veri seti olarak kullanıldı. Çoklu sınıflandırma problemlerinde kullanmak üzere, veri setine BERT derin öğrenme tekniği uygulanarak önceden eğitilmiş Türkçe bir BERT modeli üzerinde ince ayar (fine-tuning) yapıldı. Deneylerin sonucunda, eğitilmiş olan sistemin doğruluğu %96 başarım oranına sahip olmuştur.
Using Twitter Data for Cohort Studies of Drug Safety in Pregnancy: Proof-of-concept With β-Blockers
Authors: Klein Ari Z , O'Connor Karen , Levine Lisa D , Gonzalez-Hernandez Graciela
Published: June 2022

Background

Despite the fact that medication is taken during more than 90% of pregnancies, the fetal risk for most medications is unknown, and the majority of medications have no data regarding safety in pregnancy.

Objective

Using β-blockers as a proof-of-concept, the primary objective of this study was to assess the utility of Twitter data for a cohort study design—in particular, whether we could identify (1) Twitter users who have posted tweets reporting that they took medication during pregnancy and (2) their associated pregnancy outcomes.

Methods

We searched for mentions of β-blockers in 2.75 billion tweets posted by 415,690 users who announced their pregnancy on Twitter. We manually reviewed the matching tweets to first determine if the user actually took the β-blocker mentioned in the tweet. Then, to help determine if the β-blocker was taken during pregnancy, we used the time stamp of the tweet reporting intake and drew upon an automated natural language processing (NLP) tool that estimates the date of the user’s prenatal time period. For users who posted tweets indicating that they took or may have taken the β-blocker during pregnancy, we drew upon additional NLP tools to help identify tweets that report their pregnancy outcomes. Adverse pregnancy outcomes included miscarriage, stillbirth, birth defects, preterm birth (<37 weeks gestation), low birth weight (<5 pounds and 8 ounces at delivery), and neonatal intensive care unit (NICU) admission. Normal pregnancy outcomes included gestational age ≥37 weeks and birth weight ≥5 pounds and 8 ounces.

Results

We retrieved 5114 tweets, posted by 2339 users, that mention a β-blocker, and manually identified 2332 (45.6%) tweets, posted by 1195 (51.1%) of the users, that self-report taking the β-blocker. We were able to estimate the date of the prenatal time period for 356 pregnancies among 334 (27.9%) of these 1195 users. Among these 356 pregnancies, we identified 257 (72.2%) during which the β-blocker was or may have been taken. We manually verified an adverse pregnancy outcome—preterm birth, NICU admission, low birth weight, birth defects, or miscarriage—for 38 (14.8%) of these 257 pregnancies. We manually verified a gestational age ≥37 weeks for 198 (90.4%) and a birth weight ≥5 pounds and 8 ounces for 50 (22.8%) of the 219 pregnancies for which we did not identify an adverse pregnancy outcome.

Conclusions

Our ability to detect pregnancy outcomes for Twitter users who posted tweets reporting that they took or may have taken a β-blocker during pregnancy suggests that Twitter can be a complementary resource for cohort studies of drug safety in pregnancy.
A Platform for Data-Centric, Continuous Epidemiological Analyses (EpiGraphHub): Descriptive Analysis (Preprint)
Authors: Coelho Flávio , Câmara Daniel Cardoso Portela , Araújo Eduardo Correa , Bianchi Lucas Monteiro , Ogasawara Ivan , Dalal Jyoti , James Ananthu , Abbate Jessica L , Merzouki Aziza , dos Reis Izabel Cristina , Nwosu Kene David , Keiser Olivia
Published: June 2022

BACKGROUND

Guaranteeing durability, provenance, accessibility, and trust in open data sets can be challenging for researchers and organizations that rely on public repositories of data critical for epidemiology and other health analytics. The required data repositories are often difficult to locate and may require conversion to a standard data format. Data-hosting websites may also change or become unavailable without warning. A single change to the rules in one repository can hinder updating a public dashboard reliant on data pulled from external sources. These concerns are particularly challenging at the international level, because policies on systems aimed at harmonizing health and related data are typically dictated by national governments to serve their individual needs.

OBJECTIVE

In this paper, we introduce a comprehensive public health data platform, EpiGraphHub, that aims to provide a single interoperable repository for open health and related data.

METHODS

The platform, curated by the international research community, allows secure local integration of sensitive data while facilitating the development of data-driven applications and reports for decision-makers. Its main components include centrally managed databases with fine-grained access control to data, fully automated and documented data collection and transformation, and a powerful web-based data exploration and visualization tool.

RESULTS

EpiGraphHub is already being used for hosting a growing collection of open data sets and for automating epidemiological analyses based on them. The project has also released an open-source software library with the analytical methods used in the platform.

CONCLUSIONS

The platform is fully open source and open to external users. It is in active development with the goal of maximizing its value for large-scale public health studies.
The Effect Of Temperature and Time on Hydrolisis of Palm Oil Empty Fruit Bunch and Its Enzymatically Biodegradation for Xylose Production
Authors: Yulianto Wisnu Adi , Panji Dewa Made Krismanto
Published: June 2022

The acid hydrolysis and the heating of lignocellulosic waste from palm oil mills have caused irreversible damage to the natural environment and can create inhibitor compounds on hydrolysis, making the waste improper for fermentation media. In this study, an environmentally save hydrolysis was tested by heating it under high temperature which followed by enzymatic degradation. The objective of the present study was to determine the optimal reaction temperature and reaction time of hydrolysis for the production of xylose. Under the temperatures of 128 and 200°C with reactions time of 30, 45, and 60 min, the best result of hydrolysates were taken. Its hemicellulose, cellulose, lignin, water content (raw material), residual hemicellulose, reducing sugars, water content (hydrolysate) and xylose were analyzed. The results showed that the higher the temperature had resulted in the more reduction of sugar hydrolysis and the hemicellulose in the solid residue was slightly removed. Hydrolysis at the temperature of 200°C for 45 min had indicated a reduction of sugar yield of 17.71% (db). Biodegradation in enzymatic hydrolysis of xylose had increased by 113.79% at 24 -1.24 g xylose / 100 ml.
Antioxidant Level and Sensory of Dragon Fruit (Hylocereus undatus) Peel Tea Infusion Made by Partially Fermented Process
Authors: Sari Anjar Ruspita , Hardiyanti Ratih
Published: June 2022

Dragon fruits are usually consumed by people directly or being processed into juice. Therefore,the major by-product of dragon fruits is the peel. As by-product, dragon fruit peels have higherantioxidant level than pulp especially for White Dragon Fruits (Hylocereus undatus). Thisresearch is carried out in order to evaluate the antioxidant level and sensory of dragon fruitpeel tea which produced through a partially fermented process. The objective of this researchis to investigate the effect of withering time and rolling time on antioxidant level and sensory ofdragon fruit peel tea. Withering time varied in 30, 60, and 120 min while the rolling timevaried in 10, 20, and 30 sec. 2, 2, diphenyl-1-picrylhydrazil (DPPH) assay showed that radicalscavenging activities of dragon fruit peel tea infusion increased with the longer withering timeand shorter rolling time. Likewise the total phenol content (TPC) assay demonstrated theamount of phenol increased with the longer withering time and shorter rolling time. Therewere found that the dragon fruit peel had 29.58% in proportion compared with the whole fruitand vitamin C content in the peel higher than that in the pulp. The longer withering time andshorter rolling time will increase the phenol total content, antioxidant activity, and thelightness color, but decrease the acidity degree of tea infusions. In addition, the withering timewas 120 min and rolling time was 10 sec had higher Antioxidant activity 41.19% and the totalphenol 55.93 mg/L.
Assessment of Workers’ Body Temperature and Workload in Tomato Production Greenhouse Work
Authors: Silalahi Rizky , Ushada Mirwan , Fallah Mohammad Affan Fajar , Takayama Kotaro , Takahashi Noriko , Nishina Hiroshige
Published: June 2022

Many workers work in the tomato production greenhouse in Japan, exposed to unfavorable environmental conditions during their work, especially in the summer season. In this study, workers’ body temperatures of internal, facial, and head area temperature were measured, so did the workers’ workload. They were related to environmental conditions of solar radiation and air temperature to clarify their relationships. Three workers in semi-commercial tomato production greenhouse were employed for this research. Jobs were classified into upper and lower canopy job, to examine the working condition in the greenhouse. Ear thermometer and thermal camera were used to measure worker’s body temperatures. Workload of the jobs was assessed and determined the level with Heart Rate Reserve (HRR). Workers’ heart rate itselves was measured using finger pulseoxymeter. Significant correlations were found between workers’ body temperature and environmental conditions. Worker’s workload could change on changing environmental conditions. Workload level of tomato production greenhouse job is considered low, as the job relatively does not require heavy physical work.
The Best Solvent And Extraction Time In Pectin Production made From Waste Of Jackfruit (Bark and Straw)
Authors: Wignyanto Wignyanto , Rahmah Nur Lailatul , Margani Athika Dyah
Published: June 2022

Jackfruit barks are known to have fairly high pectin content, by 4.7% on wet and 22.5% on dry barks. The content is sufficiently highboy make it worthy of being raw material for producing pectin. Pectin is a polygalacturonic acid containing methyl ester. Pectin is a high- value functional food that is widely used as gelling agent and stabilizer. Approximately 65 until 80% jackfruit barks were wasted from the industry and it were only useful for animal feed . To increase the added value of it, so that jackfruit barks were extracted to get the pectin. This research used randomized block design (RBD) with 2 factors:(i)the type of solvents(hydrochloric and citric acids, with pH = 1.5) and (ii) extraction times (30, 90 and 150 minutes). Each factor is conducted in triplicate in order to get 18 units of experiment. Before analyzed, the jackfruit waste (bark and straw) was powdered during sample preparation. Later on, the yield, equivalent weight, methoxyl, galacturonic acid, and ash contents of the powdered, then were analyzed and used as pectin’s parameters. Multiple attribute method (Zeleny method) was used to determine which combination of treatments that produced pectin with the best pectin’s parameter. The best pectin made from jackfruit waste is derived from the combination of citric acid solvent and the extraction time of 150 minutes, resulting in yield of 10.21%, methoxyl content of 9.25%, equivalent weight of 1088.43 g/mol, ash content of 2.79%, and galacturonic acid content of 47.40%.
Post-harvest Quality Evolution of Jonagored Apples (Mallus domestica cv. Borkh) during Shelf life Storage
Authors: Affandi Fahrizal Yusuf , Verlinden Bert
Published: June 2022

The experiment was carried out to study the quality evolution of Jonagored apples (Mallus domestica cv. Borkh) during 14 days of shelf life prior to controlled atmosphere (CA) storage. The apple were harvested from the “Fruitteelt centrum” (Velm, Belgium) in 24 September 2010 (optimal picking) and 8 October 2010 (late picking) and were stored at 18°C and 65% RH to mimic the shelf life condition. The apple then were measured for colour, firmness, soluble solid content (SSC), titratable acidity, ethylene production rate, O 2 consumption rate, CO 2 production rate and respiratory quotient (RQ) at 0, 7 and 14 days after harvest. There was a significant effect of shelf life duration in colour of the apple. The apple turn its colour from green to yellowish green at the end of shelf life. The optimal-harvested apple had a greener colour than the late-harvested apple at 0 and 7 days of shelf life except at 14 days where the older apple had a greener colour. Although the effect was not consistent, firmness of apple was affected by shelf life and picking time as well. Firmness decreased along shelf life and the optimal-harvested apples were firmer than the late-harvested apple. Apple’s acidity decreased during shelf life from 8,43 mL NaOH (optimal-harvested apple) and 8.85 mL NaOH (late- harvested apple) to 7.58 mL NaOH (optimal-harvested apple) and 7.03 mL NaOH (late- harvested apple) at the end of shelf life. Yet, acidity was not affected by picking time. Ethylene was considerably increased throughout shelf life and the late-harvested apple had a higher ethylene production level than the optimal-harvested apple. Optimal-harvested apple had a lower respiration rate than the late picked apple. Older apple consumed oxygen and produced carbon dioxide at a higher rate than the younger apple. Moreover, respiration rates as represented by O 2 consumption rate, CO 2 production rate and respiratory quotient (RQ) tended to increase along shelf life.
Analysis of Inventory Control and Banana Chips Agroindustry Development Strategy in Bandar Lampung
Authors: Affandi M Irfan , Astuti Sussi
Published: June 2022

The study aims to analyze the performance of the inventory control and agroindustry development strategy banana chips. Site selection was done in the chips industry center Bandar Lampung City. Sampling was done offender census on members of banana agroindustry business group. Data analysis methods used was the analysis of economic order quantity (EOQ), SWOT and AHP. The results showed that the control of inventory through the ordering of raw materials and production capacity adjusted to do with intersystem messaging. The production process is generally carried out every 3 times a week with raw material price of Rp 3500,- per comb. Agroindustry development strategy banana chips were utilizing fabric of cooperation with other parties in the application of science and technology in order to produce quality products, banana chips, giving a sense of innovation so that the amount of consumer interest and increasing demand for banana chip, and optimization of infrastructure and facilities wereowned agroindustries effective and efficient.
Global Warming Potential of Nata de Coco Processing using Life Cycle Assessment Approach in CV. XYZ, Yogyakarta, Indonesia
Authors: Supartono Wahyu , Astari Annisa Dwi , Widhiarti Ratnadewi , Windayanti Wahyu , Gama Putri Ika Fajriah , Gama Siti Fathonah
Published: June 2022

Nata de coco is a well-known product in Indonesia which processed from coconut water. In the production process, the input of raw material and energy are needed to make nata de coco which the amounts are not small, as well as the amount of waste and emission which release to the environment. This study was conducted to find out how much the environmental impact in the process of making nata de coco using LCA methodology within the gate to gate scope. Analysis is carried out using functional unit on producing 1 kg of ready-to-sell nata de coco. This study was conducted by following the LCA methodology listed in ISO 14040-14043 series. The environmental impact caused by the production process of nata de coco is presented at midpoint level concentrated on global warming potential (GWP). The findings demonstrated that 0.285 kg of CO2-eq GWP were associated with 1 kg of nata de coco and firewood usage is the major contributes to the CO2 emissions.
Dampak Kebijakan Tenaga Kerja Asing Era Pemerintahan Joko Widodo (2014–2019) terhadap Tenaga Kerja Lokal di Indonesia
Authors: Martias Fara Marisda
Published: June 2022

Penetapan deregulasi pada kebijakan penggunaan tenaga kerja asing (TKA) era pemerintahan Joko Widodo (2014–2019) yang bertujuan untuk membuka lapangan pekerjaan yang seluas-luasnya serta meningkatkan pertumbuhan ekonomi melalui investasi tidak terimplementasi dengan baik. Hal ini justru memberikan kerugian bagi tenaga kerja lokal karena investasi yang didatangkan ke Indonesia turut membawa serta TKA sehingga mempersempit peluang kesempatan kerja untuk tenaga kerja lokal (TKL). Tulisan ini berupaya untuk menganalisis dampak politik dari deregulasi kebijakan TKA di Era Pemerintahan Joko Widodo terhadap TKL menggunakan teori kebijakan Theodore Lowi dan mengklasifikasikannya sebagai kebijakan regulatif. Melalui analisa kualitatif deskriptif dengan metode wawancara dan studi literatur ditemukan: (1) kebijakan penggunaan TKA dibuat pemerintah untuk mengatur melalui instrumen hukum, (2) konflik serta debat politik tidak mengubah koalisi sesuai keuntungan dan kerugian dalam arena kebijakan, hal ini disebabkan karena kurangnya partai yang berorientasi pada nasib buruh, (3) kebijakan ini dibuat dan diputuskan oleh pihak eksekutif, dan (4) keterlibatan Presiden dalam deregulasi kebijakan TKA sejak tahun 2015 dan kehadiran pengusaha dalam pusaran politik dapat menghambat tujuan deregulasi kebijakan karena konflik kepentingan.