bluuebunny/crossref_metadata_2025 huggingface dataset:
CLINICAL ADVANTAGES OF LAPAROSCOPIC CHOLECYSTECTOMY: EFFECTS ON RECOVERY AND PATIENT SATISFACTION OVER THE OPEN APPROACH
Authors: Sales Lucas Marques de Abreu , Maciel Emanuel Artur Milagres , Arias Ana Luiza de Souza Martins , Maciel João Pedro Silva Damas , Santos Marilza de Oliveira
Published: October 2024

Cholecystectomy is a surgical procedure aimed at removing the gallbladder, and is commonly used in the treatment of conditions such as symptomatic cholelithiasis and various gallbladder-related diseases. With advances in surgical techniques, laparoscopic cholecystectomy has become the preferred approach in many cases, replacing the conventional open technique. The objective of this integrative review is to analyze the advantages of laparoscopic cholecystectomy compared to conventional surgery, focusing on aspects such as recovery time, postoperative pain, complications, costs, and aesthetic results. The methodology included searches in databases such as PubMed, Scopus, and SciELO, covering studies published in the last 20 years. Inclusion criteria included systematic reviews, clinical trials, and observational studies that compared both surgical approaches. The results indicate that laparoscopic cholecystectomy offers significantly shorter recovery times, allowing patients to quickly return to daily activities. Additionally, this technique is associated with reduced levels of postoperative pain and a lower rate of complications, such as infections and hernias. The aesthetic results are also superior, with less visible scars. Although the initial costs of laparoscopy may be higher, the cost-effectiveness analysis suggests that in the long run, it may be more cost-effective due to the reduction in length of hospital stay and postoperative care. This review provides a comprehensive overview of the benefits of laparoscopic cholecystectomy and its implications for clinical practice and public health.
LEGAL TREATMENT OF THE ANTISOCIAL CONDOMINIUM OWNER IN THE LIGHT OF THE CIVIL CODE
Authors: Muniz Ítalo Bruno Cardoso , Dias Júnior Clóvis Marques
Published: October 2024

In this article, the rights and duties of the condominium owners and the legal solutions for antisocial behavior in the condominium environment were addressed, based on Brazilian legislation, specialized doctrine and judicial decisions. The objective was to understand the limitations and responsibilities of the condominium owners, analyzing how the Brazilian legal system regulates the coexistence in building condominiums. For this, a qualitative approach was used, based on documentary and jurisprudential analysis, focusing on cases judged by the Courts of Justice of São Paulo and Minas Gerais. The results of the research indicate that the legislation provides for the exclusion of the antisocial condominium owner in extreme situations, provided that the legal requirements are respected, such as the qualified quorum for deliberations. It is concluded that, although exclusion is a possible measure, it should be applied only as a last resort, and condominium coexistence requires constant mediation between the exercise of individual rights and collective interests.
ETHICAL LEADERSHIP AND WOMEN’S EMPOWERMENT: DRIVING INNOVATION AND GENDER EQUALITY
Authors: Bezerra Leticia Antonia , Oliveira Ana Paula
Published: October 2024

This paper examines the challenges faced by women in leadership positions, highlighting how machismo and patriarchal culture influence their trajectories. The research uses a bibliographic methodology, complemented by quantitative data, to analyze the evolution of female participation in the labor market. In addition, the study addresses how gender inequality affects decision-making and proposes strategies to promote greater inclusion and equity in companies, encouraging ethical leadership and valuing the role of women.
IMPLEMENTATION OF VECTOR MODULATION APPLIED TO THE THREE-PHASE DC-AC CONVERTER VSI USING A FOUR-STATE SWITCHING CELL
Authors: Reif Douglas Romeu , Hausmann Romeu , Oliveira Sérgio Vidal Garcia
Published: October 2024

This article presents the implementation of spatial vector modulation applied to the three-phase VSI converter with four-state switching cell. The methodology used is shown in detail, indicating the vectors used, the applied switching sequence and the calculations of the vector activation times. It also contains the results of the converter operation in simulation, showing the main waveforms. The following presents the results obtained by experimentation with the assembled prototype.
REGIME PROGRESSION AFTER THE ENTRY INTO FORCE OF THE ANTI-CRIME PACKAGE – LAW NO. 13,964/2019, SPECIAL REGIME PROGRESSION AND ITS BENEFICIAL ASPECTS
Authors: Cananéa Lilian Frassinetti Correia , Vilar Peterson Rodrigues Macêdo
Published: October 2024

The main purpose of this article is to analyze the changes that the Anticrime Package, Law No. 13,964/2019, in force since January 23, 2020, brought to the scope of criminal enforcement, regarding regime progression, analyzing the beneficial aspect for inmates, based on the interpretation of the Superior Courts, as well as the progression of a special regime, regarding women, and the interpretation of the Supreme Federal Court in the use of analogy in malam partem. And in order to achieve the desired proposal, the following specific objectives are followed: to make a retrospective of the fractions applied in regime progressions, in common crimes and heinous crimes, whether repeat offenders or not, highlighting the changes that have occurred, research in doctrines and jurisprudence.
PHYSIOTHERAPIST TRAINING AND INTENSIVE CARE DURING THE SARS-COV-2 PANDEMIC: AN EXPLORATORY STUDY
Authors: Braun Caroline , Rocha Júnior Paulo Roberto , Francischetti Ieda
Published: October 2024

Objective: The objective was to outline the professional profile of physiotherapists working in intensive care during the pandemic and to analyze how well their undergraduate courses met the needs of COVID-19 patients admitted to Intensive Care Units (ICUs). Method: The study was exploratory and data were collected through an electronic instrument containing closed and objective questions. Nineteen physiotherapists who worked, between March 2020 and March 2022, in ICUs caring for patients infected with COVID-19, from public and private hospitals located in the region of the Regional Health Department (DRS) IX of the state of São Paulo participated in the study. Data analysis was performed by statistical study using the “Microsoft Excel” program. Results: It was possible to observe that in the training of physiotherapists, there is a very large divergence in relation to the completion and duration of internships in the cardiorespiratory area and that the professionals had postgraduate degrees in the specific area and previous experience. It was possible to identify weaknesses in their training. Conclusion: the undergraduate course in physiotherapy partially met the needs of the job market during the pandemic. The National Curricular Guidelines (DCNs) do not ensure equity in the implementation of different curricula and thus the training of professionals does not respond, to a certain extent, to the demands of the services of the Unified Health System. Specific knowledge of the area is required after completing the undergraduate course to work in intensive care.
FIELD STUDY ON FREE PLAY AS AN ENHANCER FOR THE DEVELOPMENT OF CHILDREN'S AUTONOMY
Authors: da Rosa Alice Serrõn , Truccolo Adriana Barni
Published: October 2024

The aim of this study was to investigate the contribution of spontaneous play to the development of children's autonomy. To this end, a qualitative microethnographic study was conducted with six children, five boys and one girl, aged between two and three years old, who were part of a preschool class in kindergarten 1. They were observed daily for four months. Three thematic categories emerged from the participant observation: the importance of organizing spaces as a facilitator of free play; free play and interactions between children; and free play and the development of autonomy. The results showed that the organization of spaces interferes with free play and the development of children's autonomy; that when playing freely, children enhance symbolic play, assume roles and interact spontaneously; and when children play freely, they develop in their entirety, learning to think, question, discover, explore, and experience new discoveries. These factors are essential for the integral growth and development of children's autonomy through free play actions.
SOCIO-ENVIRONMENTAL PUBLIC POLICY FOR THE AMAZON BIOME: AN ESSAY OF THE PROAMBIENTE-POLO RIO CAPIM PROGRAM IN THE AMAZON OF PARÁ
Authors: Vasconcelos Marcelo Augusto Machado , Kato Osvaldo Ryohei , Bittencourt Paulo Celso Santiago , dos Santos Artur Vinícius Ferreira , de Melo Paulo Alves , Melo Kellem Cristina Prestes , da Silva Romulo Luiz Oliveira , de Souza Douglas Portal
Published: October 2024

From the 1990s onwards, the debate around environmental issues became increasingly present throughout the world. In this sense, the United Nations report entitled “Our Common Future”, known as the “Brundtland Report”, released in 1987, and the so-called United Nations Conference on Environment and Development (ECO-92), held in Rio de Janeiro in 1992 (FILHO-MONTIBELLER, 2001), were two events of global notoriety, in which the search for a new form of development became evident, expressed not only by environmentalists, but also by social movements. Many proposals of a socio-environmental nature were triggered from the context of society's discussion about development. The COP-30 itself, to be held in Belém-PA, was not just a forum organized under the leadership of the United Nations, it represents a historic moment where the various matrices of the global environmental movement express themselves in parallel to the official event when the idea of ​​sustainable development is based on new premises of a guiding agenda for public policies.
CANNABIDIOL AS A FORM OF TREATMENT FOR PATIENTS WITH POST-TRAUMATIC STRESS DISORDER FROM VICTIMS OF VIOLENCE – INTEGRATIVE REVIEW
Authors: Braga Cristina , Ocon Carlos Alberto , Constantino Viviane Macedo , Fernandes Antônio de Olival , Filoni Eduardo , Ribeiro Filho Alfredo , Aragão Neylor Rodrigo Oliveira , Almeida Jacqueline Cunha Cabral Azevedo , Santos Gleyce Kelly de Brito Brasileiro , Moraes Suzyanne Araújo , Douradinho Christian , Lima Lidiane Souza , Aristides Jackeline Lourenço , Marreira Marcelo , Olímpio Aloísio , Koike Marcia Kiyomi
Published: October 2024

Introduction. Violence as a social and public health problem, with a particular focus on its consequences, such as Post-Traumatic Stress Disorder (PTSD). According to the World Health Organization, violence encompasses the intentional use of physical force or power, threatening or harming individuals, groups or communities. Objective: To describe the effects of Cannabidiol on patients with Post-Traumatic Stress due to physical and psychological violence. Methodology: This is an observational and retrospective integrative systematic review, with the exclusion criteria: non-empirical articles, non-indexed publications. A total of 545 articles related to post-traumatic stress and cannabidiol were found and only 13 articles were selected to present the results of this study. Results and discussion: The endogenous endocannabinoid system plays a significant role in the processing and extinction of fear memory. Cannabidiol (CBD), a non-psychoactive component of Cannabis sativa, has shown potential in the treatment of anxiety disorders, including PTSD. CBD interacts with the endocannabinoid system indirectly by increasing the availability of endocannabinoids such as anandamide, which act on CB1 receptors in the brain. This activation of the endocannabinoid system may help reduce the behavioral response to aversive memories and improve fear extinction. Final Thoughts: While early research on the effects of CBD on PTSD is promising, more studies are needed to determine its efficacy and safety, particularly in victims of violence. Sources also emphasize the need for greater awareness and accessibility of cannabinoid-based treatments for those who may benefit from them.
THE RELATIONSHIP BETWEEN WORKLOAD AND USE OF ANXIOLYTICS AND ANTIDEPRESSANTS IN NURSING: AN INTEGRATIVE REVIEW
Authors: Borges Alan Junior dos Santos , Conartioli Ana Carolina , Lins Andreza Moreira Ribeiro , de Jesus Bruna Matos , Schibler Carlos Eduardo Michel , Oliveira Giovanna , Paganini Luiz Henrique , Scardoelli Márcia Glaciela da Cruz
Published: October 2024

Introduction: Nursing professionals face high levels of stress and work overload, which can affect their mental health and lead to the use of anxiolytics and antidepressants. However, the relationship between workload and the use of these medications is not yet completely clear. Objective: This study aims to explore the relationship between nurses' workload and the use of anxiolytics and antidepressants, in addition to identifying the main factors that influence this use. Methodology: An integrative literature review was carried out, searching the PubMed and CINAHL databases, using specific descriptors. The studies were selected based on the relationship between workload and medication use, and analyzed for quality and relevance. Conclusion: The data suggest a significant association between high workload and the use of psychotropic medications, highlighting factors such as long working hours and high demand in the health environment. The review suggests that work overload is linked to the use of anxiolytics and antidepressants by nurses, reinforcing the need for interventions to improve working conditions and support the mental health of these professionals.
ASSESSING PROGRESS TOWARDS A CIRCULAR CARBON ECONOMY IN THE G20 COUNTRIES
Authors:   PhD, Associate Professor, Faculty of Economics, and Dean of Academic Affairs at the University of East Sarajevo in Brčko, Bosnia and Herzegovina, Terzić Lejla
Published: October 2024

As cornerstones of worldwide sustainable development, the circular economy and the circular carbon economy are profoundly interrelated. However, opinions differ on how to optimize the circular economy towards reducing carbon dioxide emissions. This article aims to investigate the different levels of readiness for the circular carbon economy within G20 member countries in the domain of economic efficiency. In that regard, a selection of circular carbon economy sub-indicators has been analysed. Through the use of secondary data, tendencies towards change in this variability were found. The degree of adoption of a circular carbon economy differs among the G20 economies. In terms of the various factors considered in the G20 member countries, the current analysis has determined that there continue to be substantial differences between the best performers and their enabling factors.
FACTORS OF THE DIGITAL TRANSFORMATION
Authors:   PhD student at the Faculty of Economics and Business Administration of Sofia University „St. Kliment Ohridski“, Lazarov Simeon
Published: October 2024

The digital transformation is profoundly changing organizations and creating new comparative advantages but also necessitating new approaches to management and organizational strategy. The majority of research on business’ digital transformation focuses on technological adoption, innovation, value creation and the dynamic capabilities of organizations. However, the question of why different organizations approach the digital transformation in various ways remains less explored. This article examines the possibilities of inferring various factors that have an impact on the adoption of digital technologies in order to improve the understanding of organizations' digital transformation strategies. Factors such as size, internationalization, research and development (R&D) expenses, foreign direct investment (FDI), turnover, wages and salaries have an expected impact on the adoption of new technologies in an organization and its digital transformation. This is supported by organizational theories such as the resource-based view (RBV), the knowledge-based view (KBV) and the technology-organization-environment (TOE) frameworks. Through examples from the scientific literature, a summary is provided on how the study of the interrelationships between these factors and organizations’ digital transformation can contribute to a better understanding of the different strategies in this field.
EFFECTS OF STRIP-TILL TECHNOLOGY ON AGRICULTURAL SYSTEMS
Authors:   PhD, is Assistant Professor at the Department ", Blagoev Anton ,   Economics of Natural Resources",   , University of National and World Economy, Bulgaria
Published: October 2024

Farmers face the challenges of climate change and rising production costs, forcing them to apply the most efficient farming practices in order to achieve sustainable agriculture. More and more farmers are rethinking traditional tillage methods and introducing changes to implement more agroecological practices. Intensive farming brings with it negative consequences such as reduced soil fertility, loss of organic carbon, reduced biodiversity, and the excessive use of natural resources, which threatens sustainable agriculture. It is therefore important to place equal emphasis on both increasing crop productivity and focusing on, implementing, and using agri-environmental practices. Choosing the appropriate practice, such as working towards a no-till system or a more balanced strip-till approach, will lead to a positive impact on agriculture and the environment. The goal of this paper is to investigate the impact of agroecological practices, in particular strip-tillage, on environmental protection. The research methodology covers a literature review on the concept of strip-tillage technology, an analysis of the effects of the adoption of this technology in agriculture, and an assessment of the future prospects of strip-tillage for environmental protection.
Handbook on Proactive Contemporary Public Policies for Poverty Reduction in Bulgaria
Authors:   Dr. Ec. Sc., Professor at the University of National and World Economy, Sofia, Bulgaria, Lulanski Pano
Published: October 2024

Recently, the Publishing Complex - UNWE made available the interesting study of Dr. Ralitsa Veleva "Proactive Public Policies for Poverty Reduction". This monograph deserves attention mainly due to the still existing deficit in Bulgaria of complex analyses on the development and implementation of proactive public policies for poverty reduction. The work of the young author breaks the tradition in the Bulgarian social space to discuss extensively and in priority "welfare", and its antipode "poverty" - only as incidental touches and by the way. And it is brazenly "present on the table" of a significant part of the population, which lives this ingrained scarcity as its own social drama. What is clearly needed is, first, a professional identification of the level and trends of poverty in the country, and second, the development and implementation of credible radical instruments for its definite mitigation and containment.
Administration of oleuropein or hydroxytyrosol improves diabetic markers in obese mice
Authors: Harun Nurhidayati , Adnyana I Ketut , Damayanti Sophi , Kurniati Neng Fisheri
Published: October 2024

Context: Olive leaves are renowned for their medicinal properties in managing diabetes, primarily due to their high concentrations of hydroxytyrosol and oleuropein. Aims: To evaluate the anti-diabetic effects of hydroxytyrosol and oleuropein isolates in a mice model of obesity-induced diabetes. Methods: Male Swiss Webster mice were subjected to a high-fat diet and streptozotocin to induce obesity and diabetes, respectively. Following induction, the mice were treated with either oleuropein or hydroxytyrosol at a dosage of 20 mg/kg body weight over a period of 14 days. Fasting glucose levels, insulin sensitivity, and glucose tolerance were monitored throughout the treatment period. Additionally, histological examinations of the liver and pancreas were conducted. Furthermore, in silico docking studies were performed to assess the interactions of oleuropein and hydroxytyrosol with key metabolic receptors, including peroxisome proliferator-activated receptor gamma (PPARγ), hydroxysteroid 11-β dehydrogenase 1 (HSD11B1), and fructose-bisphosphatase 1 (FBP1). Results: Treatment with oleuropein and hydroxytyrosol led to significant reductions in fasting blood glucose levels and marked improvements in insulin sensitivity in obese and diabetic mice. These compounds also provided protective effects against pancreatic and hepatic cellular damage. In silico analyses corroborated these findings, demonstrating strong binding affinities of oleuropein and hydroxytyrosol to the targeted receptors. Conclusions: Oleuropein and hydroxytyrosol exhibit potent anti-diabetic effects in vivo, comparable to those of metformin, including glucose regulation, improved insulin sensitivity, and cellular protection. These findings suggest their potential as therapeutic agents for managing type 2 diabetes and its associated complications.
The solid-state modification for solubility enhancement of practically insoluble glimepiride: A systematic review
Authors: Darusman Fitrianti , Sopyan Iyan , Azzahra Nadya , Rusdiana Taofik
Published: October 2024

Context: Solubility is a crucial physicochemical property of pharmaceuticals that directly influences the absorption and bioavailability of drugs within the human body. Glimepiride, an oral anti-diabetic agent included in the Biopharmaceutics Classification System (BCS) class II, is practically insoluble in water. Various solid-state modification techniques have been implemented to improve the solubility of glimepiride, namely by the formation of co-crystals, co-amorphous, inclusion complexes, and solid dispersions. Aims: To systematically review the enhancement of glimepiride solubility after solid-state modifications, including co-crystals, co-amorphous, inclusion complexes, and solid dispersions. Methods: This review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 statement. The citation searches for records published in the last ten years from reputable journals. The eligibility criteria of the identified study are as follows: Population (P): Glimepiride is practically insoluble in water; Intervention (I): Solid-state modification of glimepiride includes co-crystals, co-amorphous, inclusion complexes, and solid dispersions; (C): Glimepiride raw material before solid-state modification; and Outcome (O): Solubility and dissolution enhancement. ADA tool was used to assess the quality of the records. Results: A total of 5,220 records were found. The duplicates and undesired articles were excluded. 14 relevant records were further identified through citation searching. The screening and exclusion of records based on the inclusion and exclusion criteria left 13 eligible studies. The studies show that solid-state modification, including co-crystals, amorphous, inclusion complexes, and solid dispersions, can enhance the solubility of practically insoluble glimepiride. Conclusions: Solid-state modification could improve the solubility and dissolution of glimepiride.
Unlocking the Secrets of Pheromones: Reproductive and Social Communication in Domestic Mammals
Authors: Dharani K. , Abinaya P. , J Violet Beaulah , Sridevi P. , Gnanadevi R. , Kannan T. A.
Published: October 2024

Pheromones play a pivotal role in the reproductive and behavioural management of livestock, influencing various physiological and behavioural responses within and across species. This review explores the application of pheromones in cattle, buffalo, sheep, goats, pigs, and equines, highlighting their significant impact on reproductive efficiency, stress reduction, and animal welfare. In cattle, pheromones are essential for estrus detection and the enhancement of maternal bonding. Similarly, in buffaloes, urinary pheromones have been identified as markers for estrus detection, aiding in overcoming the challenge of silent ovulation, while also contributing to penis erection and sperm quantity enhancement. In small ruminants such as sheep and goats, the "male effect" accelerates puberty and synchronizes estrus, which is crucial for optimizing breeding cycles. In pigs, the presence of boars accelerates puberty in gilts and reduces postpartum anestrus in sows, enhancing reproductive outcomes. Equines benefit from appeasing pheromones, which alleviate stress in foals and adult horses, particularly during transportation and other stressful events. The synthesis and application of synthetic analogs of these pheromones have demonstrated practical benefits in animal husbandry, offering promising avenues for improving reproductive performance and animal welfare. However, despite these advancements, the identification and characterization of specific pheromones across different species remain incomplete. Future research should focus on the molecular identification of these pheromones, their mechanisms of action, and the development of innovative applications to further enhance their utility in animal management.
Ornamental Fish Diversity in Some Selected Water Bodies of the Upper Brahmaputra Basin in Assam, India
Authors: Deb Shatabdi , Sonowal Jyotirmoy , Biswas Shyama Prasad
Published: October 2024

The northeastern region of India is renowned for its rich repository of ornamental fish. Though the majority of them constitute a rich source of dietary protein, many of them are also sourced as ornamental fish from the region. Among different states in the region, Assam is blessed with a huge repository of ornamental fish resources that are found to occur naturally in a variety of freshwater habitats. The present investigation deals with the diversity of ornamental fishes in prominent fish assemblage areas of the state. A total of 49 ornamental fish species were recorded represented by 32 genera under 18 families and 8 orders from the studied water bodies. Among the water bodies, R. Dibru accounted for the highest number of species, i.e. 46 ornamental fishes belonging to              31genera under 18 families. Mer Beel and R. Burhidihing recorded the lowest number of species. The findings of the present investigation provide crucial information on diversity in the study area, which would be helpful in better management and conservation of ornamental fish in the region.
Chlorella sp. inmovilizada con aplicación en el tratamiento, monitoreo de agua y producción de biomasa
Authors: Vizcaíno-Rodríguez Luz Adriana , Aguilar-Corona Nereida Yuriko , Caro-Becerra Juan Luis , Mayoral-Ruíz Pedro Alonso , Michel-Parra J. Guadalupe
Published: October 2024

La aplicación de microalgas en procesos de biorremediación tiene como fin remover componentes tóxicos y excesos de iones que causan eutrofización. Las algas emplean el exceso de nutrientes presentes en el agua, para producir biomasa mediante fotosíntesis. Las microalgas son utilizadas en el monitoreo ambiental, dichos organismos son sensibles ante contaminantes tanto naturales como antropogénicos, los cuales promueven o inhiben el crecimiento celular y poblacional. El presente estudio tuvo como objetivo la determinación de una matriz óptima para la inmovilización de Chlorella sp. la cual es una especie nativa de la región. Las matrices ensayadas fueron alginato de calcio al 4 % y alginato- agar 4 %. Para el cultivo se empleó medio Bold ́s y se realizó una cinética de crecimiento por cada tratamiento en cultivo tipo Bach, durante 21 días de incubación. Las variables de respuesta fueron: la concentración celular máxima, la viabilidad celular y la conservación de las esferas. La concentración celular máxima fue de 1.07x106 células. mL-1 y se alcanzó a los 15 días de cultivo, en esferas de alginato al 4 %. El tiempo de duplicación fue de 0.162 y 0.141 para Chlorella sp. retenida en matriz de alginato 4 % y agar-alginato 4 %, respectivamente. Respecto a la calidad de esferas, a los 15 días de cultivo, inició el proceso de desintegración del sistema de inmovilización alginato-agar. Las esferas de alginato permanecieron sin cambios durante los 21 días del experimento. En conclusión, el mejor tratamiento para la inmovilización de Chlorella se obtuvo cuando se empleó el alginato al 4 % y se recomienda continuar los estudios para el desarrollo del sistema de biorremediación, producción de biomasa y biosensores. Se establecieron las condiciones de inmovilización para el cultivo de Chlorella sp. en matriz de alginato de calcio.
Obtención de carbones activados a partir de residuos agroindustriales mediante activación química con ácido fosfórico para la adsorción de azul de metileno
Authors: Canales-Flores Roberto Antonio , Prieto-García Francisco
Published: October 2024

Actualmente, los residuos agrícolas y forestales han encontrado uso como materia prima para otras aplicaciones. En esta investigación se obtuvieron carbones activados (CA) de cascarilla de cebada (BHA), mazorca de maíz (CCA) y hojas de Agave salmiana (ALA) mediante activación química con ácido fosfórico para la adsorción de azul de metileno (MB). Se utilizó un diseño experimental L9, basado en la metodología Taguchi, para maximizar el rendimiento de CA. La concentración del agente de activación (Factor A), el tiempo de activación (Factor B), la temperatura de activación (Factor C) y el flujo de nitrógeno (Factor D) fueron los factores de control para la activación química. El factor ruido fue el precursor. Se investigó el efecto de los factores de control sobre el rendimiento de CA y las capacidades de adsorción de MB. La relación S/R se analizó mediante análisis de varianza (ANOVA). Las condiciones óptimas para el proceso de activación química fueron: H3PO4 al 30% (nivel 1), tiempo de activación de 60 min (nivel 2), temperatura de activación de 300 °C (nivel 1) y flujo de nitrógeno de 100 cm3/min (nivel 1). Se obtuvieron CA con estructuras mesoporosas y cargas superficiales aniónicas. Las Qmax de MB y los rendimientos de CA fueron de 11.61 mg g-1 y 68% para ALA, 84.89 mg g-1 y 66% para CCA, 86.14 mg g-1 y 87% para BHA, respectivamente. A partir de estos hallazgos, se estableció que los olotes de maíz, la cascarilla de cebada y las hojas de agave son buenos precursores para la producción de CA.
Percepción del impacto ambiental en las comunidades de origen de los estudiantes de propedéutico, UACh, México
Authors: Castillo Beltrán Martha
Published: October 2024

El presente trabajo consistió en la percepción que tiene el estudiante sobre el Impacto Ambiental (IA) de 22 comunidades rurales en donde residen. Se empleó el método cualitativo y exploratorio, con el propósito de analizar la percepción del impacto ambiental que se genera en las comunidades, los problemas y las causas del deterioro, así como promover la conservación y preservación de los recursos del medio ambiente con acciones de aprendizaje-servicio. El material esencial utilizado radicó en guías de aprendizaje sobre problemas ambientales (cambio climático, energía, efecto invernadero e impacto ambiental) y 2 grupos focales para el efectuar el IA. Los resultados mostraron que el uso de plásticos, exceso de uso de transporte y electrodomésticos, los desechos orgánicos, los pesticidas y fertilizantes usados para la floricultura, “cuetes” para fiestas, quema de basura y no reciclarla, generan y repecurten en el cambio climático, así, como los desastres ambientales que han observado en sus comunidades contaminación por basura, socavones, contaminación por camiones de contrucción, desechos tóxicos, tala, exceso de incendios, inundaciones, sequías, agua contaminada. Sin embargo, en algunas casas emplean ecotecnologías como son los calentadores solares, huertos caseros, biodigestores, baños secos, recolecta de agua de lluvia, fotoceldas, etc.. Finalmente, se pueden mitigar los problemas ambientales promoviendo la participación con acciones ambientales en el desarrollo de una sociedad sustentable inclusiva, siendo solidarios, como un proceso de concientización y promoción social.
Ingeniería Multidisciplinaria: Investigaciones y Aplicaciones Modernas y Sustentables
Authors: Agualongo Wilson G. , Analuiza Byron D. , Poma Juan P. , Vistin Ángel L. , García Jimmy D. , Pozo Jhony P. , Mora Alex F. , Remache Angelito G. , Barragán Rommel A. , Guastay Washington E. , Chávez José N. , Gáleas Zoila M. , Lema Paul A. , Remache Milton X. , Cañar Willam P. , Armendariz Jaime A.
Published: October 2024

La ingeniería multidisciplinaria ha surgido como un enfoque vital para abordar desafíos complejos en el mundo rápidamente cambiante de hoy, implica la integración de varias disciplinas de ingeniería, como la ingeniería mecánica, civil, eléctrica y ambiental, para crear soluciones innovadoras que no solo sean efectivas sino también sustentables. Los proyectos que involucran tecnologías de reciclaje y procesamiento sustentable de desechos se benefician de conocimientos de distintas disciplinas de ingeniería, lo que en última instancia conduce a un planeta más saludable. Por lo tanto, la invitación es leer este libro donde en 4 artículos se evidencia el compromiso con la investigación, la innovación y por supuesto, con mejorar la calidad de vida de la sociedad por parte de profesionales de la ingeniería..
Etnobotánica de la Cultura Ancestral Florística de la Comunidad Kichwa Quindihua
Authors: Peña Guamán Carlos Oswaldo , Guerrero Tipantuña Mario Rubén , Sánchez Guerrero Daniel Oswaldo , Lema Pillalaza Jaime René , Romo Rojas Mario Giovanni
Published: October 2024

De todas las etnias que viven dentro del territorio ecuatoriano, el presente estudio se centró en el pueblo milenario de Waranka, uno de los pueblos milenarios con un cúmulo inmenso de saberes o conocimientos que vienen de ser practicados desde las épocas ancestrales, asentado en el centro de la Provincia Bolívar, en plena sierra, a una altura de 2500 m s. n. m. y a 3500 m s. n. m., presente en los cantones de Guaranda. Este texto de etnobotánica es una contribución muy importante para el conocimiento de nuestra riqueza en biodiversidad, además de un acercamiento válido a la rica cultura de las etnias y sus conocimientos ancestrales de la Naturaleza., a la cual rinde respeto y veneración.
Moderate Intensity Interval Training (MIIT) and High Intensity Interval Training (HIIT) exercise therapy against irisin levels in obesity
Authors: Riwayadi Didib , Ambardini Rachmah Laksmi , Sutapa Panggung , Hardianto Deni , Ali Syed Kamaruzaman Syed , Karakauki Manil , Aryanto Sherif Juniar , Pratama Kukuh Wahyudin , Utami Danarstuti , Kristianto Agus
Published: October 2024

Obesity can cause physiological disorders. These physiological disturbances cannot be separated from the roles of irisin. Exercising with the right measure, measurable, and regularly is a strategy for dealing with obesity. The aims of this study were (1) to determine the effect of irisin levels on exercise with the Moderate Intensity Interval Training (MIIT) and High Intensity Interval Training (HIIT) levels models in obese rats.
This research is a true experimental laboratory study with a pretest-posttest control group design. This research was conducted at the Bioscience Laboratory of Brawijaya University, Malang. The research sample used 27 obese male Wistar rats divided into 9 MIIT group rats, 9 HIIT rats, and 9 control rats. Exercise intervention is given for 6 weeks at a frequency of 4 times per week. The intensity of MIIT (60–80% of base line ability), HIIT (90–100% of base line ability), irisin levels are obtained from blood tests using enzyme-linked immunosorbent assay (ELISA). Data analysis used the Anova test and post hoc Tukey analysis with a significance level of 0.01.
The results showed that there was no significant difference in irisin levels (p = 0.507). The HIIT irisin difference was lower than MIIT (p = 0.932) and Control (p = 0.491), and there was no difference in irisin value between the MIIT and Control groups (p = 0.708).
Geisterbahn in die Zukunft
Authors: Behrendt Eva
Published: October 2024

Jan-Christoph Gockel fährt in Frankfurt mit Goethes «Faust 1&2» Geisterbahn – und Wilke Weermann philosophiert in seiner Boulevardkomödie «Alle Zeit der Welt» über Tourismus in die Vergangenheit

Von Eva Behrendt
Vervielfacht, vereinfacht
Authors: Pesl Martin Thomas
Published: October 2024

Die neue Burg-Direktion nimmt Fahrt auf – neben Therese Willstedts «Orlando»-Adaption stehen zwei Solos auf dem Programm: Thomas Bernhards «Holzfällen» mit Nicolas Ofczarek und Stefan Zweigs «Schachnovelle» mit Nils Strunk

Von Martin Pesl
Frohe Botschaften
Authors: Tschirner Christian , Musiol Lynn Takeo
Published: October 2024

... führen zu mehr queer joy. Lassen sich die Theater darauf ein? Und «Theater heute»?

Von Lynn T Musiol und Christian Tschirner
Development and Challenges of Maglev Transportation
Authors: Huang Huan , Li Haitao , Sun Yougang , Hu Xiao
Published: October 2024

Magnetic levitation (Maglev) transportation and Evacuated Tube Transportation (ETT) represent cutting-edge advancements in high-speed travel. Maglev trains utilize powerful magnets to levitate above the tracks, eliminating friction and allowing for extremely high speeds, and typically have a wide speed range. Since the 1960s, Germany has developed Maglev transportation technology to a mature stage for engineering application, providing new options for the further development of high-speed ground transportation. This technology is already in use in countries like Japan and China, offering efficient, fast, and smooth travel experiences. This chapter examines the development and application of Maglev and ETT. We divide the existing magnetic levitation systems into two categories: active electromagnetic suspension (EMS) and passive Maglev, which includes superconducting electrodynamic suspension (EDS) and pinning Maglev. It begins by analyzing the experience of existing commercial lines for medium- and low-speed EMS transportation, followed by a discussion of the advancements in high-speed EMS transportation. Then, this chapter explores the current status of passive Maglev transportation systems, with a focus on superconducting EDS and superconducting pinning Maglev technologies. Lastly, it reviews the research progress on ETT-Maglev systems and considers potential projects, highlighting the future possibilities of this cutting-edge technology.
Innovative Strategies for Remote Patient Management in Peritoneal Dialysis: The Role of Artificial Intelligence
Authors: Biswas Ratnadeep
Published: October 2024

The integration of artificial intelligence (AI) and telehealth in peritoneal dialysis (PD) marks a paradigm shift in chronic kidney disease care. In conventional PD practice, poor adherence to prescriptions leads to increased complications, hospitalizations, and mortality, while delays in care and inefficient oversight contribute to higher healthcare costs and workload burdens. Addressing these unmet needs is critical for improving patient outcomes. This chapter explores the evolution of remote patient management (RPM) in PD, emphasizing AI’s transformative role in enhancing patient outcomes through real-time monitoring, predictive analytics, and personalized care plans. The historical progression from basic telemedicine to sophisticated AI-driven systems highlights the potential for reduced hospitalizations and improved treatment adherence. Despite the benefits, obstacles such as digital access, data security, disparities, and the need for specialized training persist. Ethical considerations, including patient autonomy and algorithmic bias, are also crucial in the responsible deployment of these technologies. As advancements in AI and telehealth continue, their role in managing PD is poised to expand, resulting in enhanced health outcomes and a better quality of life for patients.
Topology Optimization for Metal Additive Manufacturing: Effect of Build Orientation and Overhang Constraint
Authors: Dangal Babin , Boppana Harshith , Jung Sangjin
Published: October 2024

Additive manufacturing (AM) is an advanced manufacturing technology that offers significant advantages for producing complex geometries, but it also presents unique challenges, particularly in managing overhangs and selecting appropriate build orientations. Overhangs, which are unsupported features that extend beyond the main structure, can lead to defects such as warping, sagging, and incomplete fusion during fabrication. To address these challenges, this chapter explores the integration of overhang constraints and build orientation as critical factors in the topology optimization process for AM. The study demonstrates that incorporating overhang constraints into the optimization algorithm can significantly reduce the need for support structures, thereby minimizing material usage, post-processing requirements, and overall manufacturing costs. Additionally, this chapter examines the effect of build orientation on the optimized geometry, highlighting how changes in orientation can dramatically affect the volume of support structures and the manufacturability of the final part. We also show that fixing the build orientation for AM in a particular orientation and then performing topology optimization often fails to produce a converged, feasible design solution. The findings underscore the need for a holistic approach to design optimization for metal additive manufacturing, where these AM design factors are simultaneously optimized to achieve practical and efficient designs.
Sustainable Production of Certified Beef Cattle Farming in the Pantanal
Authors: Gomes Pinto de Abreu Urbano , Gonçalves Gomes Eliane , Henrique Ribeiro Balduino Silvio
Published: October 2024

The Pantanal is a Brazilian biome with a peculiar beef cattle production system. In November 2018, the Government of Mato Grosso do Sul, Brazil, approved legislation that made the tax incentive for organic and sustainable meat production official. Despite the initial difficulty in organizing the production chain and, in parallel, going through 2 years of pandemic, in 2022 the production system was consolidated. In order to evaluate the progress of the sustainable and organic meat production system in the Pantanal, data from nine slaughterhouses accredited by the Pantanal Sustainable Livestock Program were subjected to unstructured modeling using the K-means method. Two groups were identified (C1 and C2). The first (C1) had a smaller number of animals per batch, and most batches had females. Group C2 had a larger number of animals, mainly males. C1 and C2 received, respectively, 53 and 47% of the total tax exemption (BRL 8,495,587.53). The development of a sustainable livestock system with quality and certification for bovine at slaughter proved to be an important option for the development of livestock farming in the Pantanal.
Mapping Entrepreneurial Competences for the Cultural and Creative Industries: An Application of the European Entrepreneurship Competence Framework to Course Design
Authors: Durão Marília , Fernandes Sandra , Nogueira Sónia , Neves Augusto
Published: October 2024

Entrepreneurial education for the Cultural and Creative Industries (CCIs) has gained visibility in educational settings, notably higher education institutions, fostering a business-driven approach to creativity and value in cultural and artistic production. At the core of this approach lies the development of an entrepreneurial mindset, a principle underscored by the European Entrepreneurship Competence Framework (EntreComp). This framework serves as the European benchmark for initiatives promoting entrepreneurial learning, such as the project ‘Fostering Entrepreneurship and Innovation in Cultural and Creative Industries through Interdisciplinary Education’ (FENICE), developed under the Erasmus+ Program of the European Union. Drawing on the insights gained from the FENICE project, this conceptual work outlines the application of EntreComp in designing a teaching program aimed at bridging existing skill gaps in entrepreneurship within the CCIs, cultivating an entrepreneurial mindset, and promoting key competencies outlined in EntreComp. This chapter underscores the importance of aligning educational initiatives with EntreComp to equip students with managerial capabilities and foster entrepreneurial skills, tailoring the curricula with entrepreneurial learning outcomes that align with the unique context of the cultural and creative sector. Nevertheless, limitations are to be acknowledged, including the absence of empirical data to evaluate the actual progression of entrepreneurial competencies among students and the necessity for nurturing an entrepreneurial culture and refining educational frameworks within the CCIs.
Health-Related Quality of Life (HRQoL) in COVID-19 Patients After Recovering from the Acute Infection
Authors: Firouzabadi Dena , Mahmoudi Laleh , Kadkhodamohammadi Maryam , Niknam Ramin , Amanati Ali
Published: October 2024

Background: Nearly four years after the COVID-19 outbreak, its burden persists, with long-term physical and mental impacts still being discovered. Objectives: Given that these effects may vary across different periods post-infection and in diverse cultural, medical, and economic settings, we aimed to evaluate the health-related quality of life (HRQoL) in Iranian patients six months after acute infection. Methods: A total of 194 infected patients were enrolled and re-evaluated six months after the onset of acute infection. Health-related quality of life was assessed using the validated EQ-5D-3L questionnaire. Results: The mean age of patients was 50.1 ± 15.8 years, with a female-to-male ratio of 1.04. Diabetes mellitus and hypertension were the most common comorbidities. Significant impairment was observed in all categories of HRQoL after recovery from acute COVID-19 infection (P-value < 0.05). Female gender, older age, and intensive care unit admissions were independent factors associated with worsened health status post-recovery. The overall reduction in post-COVID-19 infection quality of life (QoL) score was 25%. Conclusions: The mental and physical burden of COVID-19 in our study population was considerable. Comorbid conditions and a lack of supportive measures post-infection, especially in a low-income country, may contribute to the long-term effects of COVID-19.
Investigation of the Effectiveness of Tocilizumab on COVID-19 Patients: A Retrospective Study
Authors: Khodabakhshi Behnaz , Masoumifar Romina , Mazandarani Mahdi , Lashkarbolouk Narges , Roshandel Gholamreza
Published: October 2024

Background: Tocilizumab (TCZ), an interleukin-6 receptor inhibitor, has been considered a potential treatment for severe COVID-19 cases. However, data on its effectiveness remain limited. Objectives: This study aims to evaluate the outcomes of using TCZ in patients with severe COVID-19 during the fifth wave of the pandemic. Methods: This retrospective cohort study was conducted on 114 patients with severe COVID-19 who were hospitalized in the ICU at Sayyad Shirazi Hospital in Gorgan, Iran, during the fifth wave. The patients were divided into two groups: 57 received TCZ along with standard treatment (remdesivir and corticosteroids), while 57 received only standard treatments. Results: The mean age of the participants was 53.02 ± 17.29 years, with 54.4% being female. The mean length of hospitalization was 20.16 ± 17.30 days. Statistical analysis showed no significant differences regarding age (P = 0.34), gender (P = 0.25), or length of hospitalization (P = 0.84). Additionally, 43.9% of the participants had underlying health conditions, with no significant difference in their distribution (P = 0.70). The intubation rate was 3.5% in the TCZ group compared to 5.3% in the control group, with no significant association between the two groups (P = 0.64). Mortality rates were 47.4% (27 patients) in the TCZ group and 56.1% (32 patients) in the control group, with statistical analysis revealing no significant difference between the two groups (P = 0.34). However, in patients aged 60 years and older, the mortality rate was significantly higher in the control group than in the TCZ group (P = 0.03). Conclusion: The use of TCZ in severe COVID-19 patients hospitalized in the ICU was associated with a reduced mortality risk among patients aged 60 years and older.