bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Methods from SOX2 Expression Associates with Stem Cell State in Human Ovarian Carcinoma
Authors: Bareiss Petra M. , Paczulla Anna , Wang Hui , Schairer Rebekka , Wiehr Stefan , Kohlhofer Ursula , Rothfuss Oliver C. , Fischer Anna , Perner Sven , Staebler Annette , Wallwiener Diethelm , Fend Falko , Fehm Tanja , Pichler Bernd , Kanz Lothar , Quintanilla-Martinez Leticia , Schulze-Osthoff Klaus , Essmann Frank , Lengerke Claudia
Published: April 2023

PDF file, 99K, Includes additional information regarding Primer Sequences used for Real Time PCR analysis, Tissue Microarray Analysis, Lentiviral transduction, and PET/MRI analysis.
Supplementary Figure Legends from Vaccine-Instructed Intratumoral IFN-γ Enables Regression of Autochthonous Mouse Prostate Cancer in Allogeneic T-Cell Transplantation
Authors: Hess Michelini Rodrigo , Manzo Teresa , Sturmheit Tabea , Basso Veronica , Rocchi Martina , Freschi Massimo , Listopad Joanna , Blankenstein Thomas , Bellone Matteo , Mondino Anna
Published: April 2023

PDF - 80K
Supplementary Table S1 from Histone Demethylase RBP2 Promotes Lung Tumorigenesis and Cancer Metastasis
Authors: Teng Yu-Ching , Lee Cheng-Feng , Li Ying-Shiuan , Chen Yi-Ren , Hsiao Pei-Wen , Chan Meng-Yu , Lin Feng-Mao , Huang Hsien-Da , Chen Yen-Ting , Jeng Yung-Ming , Hsu Chih-Hung , Yan Qin , Tsai Ming-Daw , Juan Li-Jung
Published: April 2023

Supplementary Table S1 - PDF file 159K, RBP2-regulated genes involved in tumorigenesis and metastasis
Supplementary Movie 7 from CIP4 Controls CCL19-Driven Cell Steering and Chemotaxis in Chronic Lymphocytic Leukemia
Authors: Malet-Engra Gema , Viaud Julien , Ysebaert Loïc , Farcé Manon , Lafouresse Fanny , Laurent Guy , Gaits-Iacovoni Frédérique , Scita Giorgio , Dupré Loïc
Published: April 2023

AVI file - 2141K, Supplemental Movies 6-8 shows Time-lapse video-recording of zoomed sections of the lamellipodium of a representative JVM3 cell expressing GFP-CIP4 and migrating in a CCL19 gradient. The four panels show GFP-CIP4 (green), pseudo-colour scale indicating CIP4 level, transmission and merge.
Supplementary Movie 3 from Histone Demethylase RBP2 Promotes Lung Tumorigenesis and Cancer Metastasis
Authors: Teng Yu-Ching , Lee Cheng-Feng , Li Ying-Shiuan , Chen Yi-Ren , Hsiao Pei-Wen , Chan Meng-Yu , Lin Feng-Mao , Huang Hsien-Da , Chen Yen-Ting , Jeng Yung-Ming , Hsu Chih-Hung , Yan Qin , Tsai Ming-Daw , Juan Li-Jung
Published: April 2023

Supplementary Movie 3 � MOV file 1911K, cell moving in RBP2 KD2
Supplementary Figure Legends and Table Legend from Epimorphin Is a Novel Regulator of the Progesterone Receptor Isoform-A
Authors: Bascom Jamie L. , Radisky Derek C. , Koh Eileen , Fata Jimmie E. , Lo Alvin , Mori Hidetoshi , Roosta Neda , Hirai Yohei , Bissell Mina J.
Published: April 2023

PDF file, 77K.
Supplementary Figure 2 from Superior Penetration and Retention Behavior of 50 nm Gold Nanoparticles in Tumors
Authors: Huo Shuaidong , Ma Huili , Huang Keyang , Liu Juan , Wei Tuo , Jin Shubin , Zhang Jinchao , He Shengtai , Liang Xing-Jie
Published: April 2023

PDF file - 244K, Characterization of 50 nm and 100 nm Au@tiopronin NPs in relevant biological media
Supplementary Methods , Figure Legend from ABL Regulation by AXL Promotes Cisplatin Resistance in Esophageal Cancer
Authors: Hong Jun , Peng DunFa , Chen Zheng , Sehdev Vikas , Belkhiri Abbes
Published: April 2023

PDF file - 60K
Supplementary Figures 1-7 from Novel Oncogene–Induced Metastatic Prostate Cancer Cell Lines Define Human Prostate Cancer Progression Signatures
Authors: Ju Xiaoming , Ertel Adam , Casimiro Mathew C. , Yu Zuoren , Meng Hui , McCue Peter A. , Walters Rhonda , Fortina Paolo , Lisanti Michael P. , Pestell Richard G.
Published: April 2023

PDF file - 675KB, Supplementary Figure 1: Histology of tumors induced by transformed prostate cancer cell lines in mice. Supplementary Figure 2: vWF and KLK3 staining of tumors induced by transformed cell lines. Supplementary Figure 3: Gene Ontology enrichment analysis. Supplementary Figure 4: c-Myc prostate cancer cell line gene expression. Supplementary Figure 5: Kaplan Meier curves for high and low expression populations for the c-Myc overexpression signature. Supplementary Figure 6: Androgen responsiveness of transformed PEC lines. Supplementary Figure 7: CK5 or CK8 IFC staining in cell lines and tumor lung metastasis.
Supplementary Figure 8 from An Antibody That Locks HER3 in the Inactive Conformation Inhibits Tumor Growth Driven by HER2 or Neuregulin
Authors: Garner Andrew P. , Bialucha Carl U. , Sprague Elizabeth R. , Garrett Joan T. , Sheng Qing , Li Sharon , Sineshchekova Olga , Saxena Parmita , Sutton Cammie R. , Chen Dongshu , Chen Yan , Wang Huiqin , Liang Jinsheng , Das Rita , Mosher Rebecca , Gu Jian , Huang Alan , Haubst Nicole , Zehetmeier Carolin , Haberl Manuela , Elis Winfried , Kunz Christian , Heidt Analeah B. , Herlihy Kara , Murtie Joshua , Schuller Alwin , Arteaga Carlos L. , Sellers William R. , Ettenberg Seth A.
Published: April 2023

PDF file - 181K, Figure S8. PIK3CA mutation is associated with reduced activity contributed by Trastuzumab (T) in Trastuzumab + LJM716 (L) combinations.
Supplementary Figure 3 from Intestinal Bacteria Modify Lymphoma Incidence and Latency by Affecting Systemic Inflammatory State, Oxidative Stress, and Leukocyte Genotoxicity
Authors: Yamamoto Mitsuko L. , Maier Irene , Dang Angeline Tilly , Berry David , Liu Jared , Ruegger Paul M. , Yang Jiue-in , Soto Phillip A. , Presley Laura L. , Reliene Ramune , Westbrook Aya M. , Wei Bo , Loy Alexander , Chang Christopher , Braun Jonathan , Borneman James , Schiestl Robert H.
Published: April 2023

PDF file - 197K, Phyla Legend.
Supplementary Figure 2 from MIG-7 Controls COX-2/PGE2-Mediated Lung Cancer Metastasis
Authors: Ho Ming-Yi , Liang Shu-Mei , Hung Shao-Wen , Liang Chi-Ming
Published: April 2023

PDF file - 171K, Knockdown of EP4 attenuates the effects of PGE2
Supplementary Figure 1 from MIG-7 Controls COX-2/PGE2-Mediated Lung Cancer Metastasis
Authors: Ho Ming-Yi , Liang Shu-Mei , Hung Shao-Wen , Liang Chi-Ming
Published: April 2023

PDF file - 229K, Knockdown of COX-2 downregulates migration and invasive abilities of lung cancer cells that express MIG-7 protein
Supplementary Video 2 from Identification of Two Distinct Carcinoma-Associated Fibroblast Subtypes with Differential Tumor-Promoting Abilities in Oral Squamous Cell Carcinoma
Authors: Costea Daniela Elena , Hills Allison , Osman Amani H. , Thurlow Johanna , Kalna Gabriela , Huang Xiaohong , Pena Murillo Claudia , Parajuli Himalaya , Suliman Salwa , Kulasekara Keerthi K. , Johannessen Anne Chr. , Partridge Max
Published: April 2023

MP4 file - 1035K, 1. Time-lapse microscopy of NF6 plated onto collagen I showing NF movement, with motile cells with shorter tracks. Images were captured every 10 mins and analysed using IMARIS software. The centre of each CAF is marked by a grey square. Migration was visualized by a track that changes colour in time as shown by the scale lower right corner. Quantification of the migration is shown in supplementary Table ST1.
Supplementary Figure 6 from PD-1–Expressing Tumor-Infiltrating T Cells Are a Favorable Prognostic Biomarker in HPV-Associated Head and Neck Cancer
Authors: Badoual Cécile , Hans Stéphane , Merillon Nathalie , Van Ryswick Cordélia , Ravel Patrice , Benhamouda Nadine , Levionnois Emeline , Nizard Mevyn , Si-Mohamed Ali , Besnier Nicolas , Gey Alain , Rotem-Yehudar Rinat , Pere Hélène , Tran Thi , Guerin Coralie L. , Chauvat Anne , Dransart Estelle , Alanio Cécile , Albert Sebastien , Barry Beatrix , Sandoval Federico , Quintin-Colonna Françoise , Bruneval Patrick , Fridman Wolf H. , Lemoine Francois M. , Oudard Stephane , Johannes Ludger , Olive Daniel , Brasnu Daniel , Tartour Eric
Published: April 2023

PDF file - 4.8MB, Synergy between anti-HPV vaccine and anti-PDL-1 to inhibit tumor growth
Supplementary Figure 3 from PD-1–Expressing Tumor-Infiltrating T Cells Are a Favorable Prognostic Biomarker in HPV-Associated Head and Neck Cancer
Authors: Badoual Cécile , Hans Stéphane , Merillon Nathalie , Van Ryswick Cordélia , Ravel Patrice , Benhamouda Nadine , Levionnois Emeline , Nizard Mevyn , Si-Mohamed Ali , Besnier Nicolas , Gey Alain , Rotem-Yehudar Rinat , Pere Hélène , Tran Thi , Guerin Coralie L. , Chauvat Anne , Dransart Estelle , Alanio Cécile , Albert Sebastien , Barry Beatrix , Sandoval Federico , Quintin-Colonna Françoise , Bruneval Patrick , Fridman Wolf H. , Lemoine Francois M. , Oudard Stephane , Johannes Ludger , Olive Daniel , Brasnu Daniel , Tartour Eric
Published: April 2023

PDF file - 2.6MB, Relationship between tumor infiltration with Foxp3 regulatory T cells and survival
Supplementary Table 1 from Trop-2 Promotes Prostate Cancer Metastasis By Modulating β1 Integrin Functions
Authors: Trerotola Marco , Jernigan Danielle L. , Liu Qin , Siddiqui Javed , Fatatis Alessandro , Languino Lucia R.
Published: April 2023

PDF file - 30K, List of Antibodies used in this study.
Supplementary Figure 5 from Synergistic Induction of Adaptive Antitumor Immunity by Codelivery of Antigen with α-Galactosylceramide on Exosomes
Authors: Gehrmann Ulf , Hiltbrunner Stefanie , Georgoudaki Anna-Maria , Karlsson Mikael C. , Näslund Tanja I. , Gabrielsson Susanne
Published: April 2023

PDF file - 54K, Late onset treatment using aGC-loaded exosomes leads to T cell infiltration into the tumor, increased survival and decreased tumor growth.
Supplementary Figure 6 from Trop-2 Promotes Prostate Cancer Metastasis By Modulating β1 Integrin Functions
Authors: Trerotola Marco , Jernigan Danielle L. , Liu Qin , Siddiqui Javed , Fatatis Alessandro , Languino Lucia R.
Published: April 2023

PDF file - 164K, Surface expression levels of wild type and Δcyto Trop-2 in PC3-2 transfectants.
Supplementary Tables 1 - 2 from Cytotoxic Activity of Tivantinib (ARQ 197) Is Not Due Solely to c-MET Inhibition
Authors: Katayama Ryohei , Aoyama Aki , Yamori Takao , Qi Jie , Oh-hara Tomoko , Song Youngchul , Engelman Jeffrey A. , Fujita Naoya
Published: April 2023

PDF file - 37K, Genetic status of the cell lines used in this study (S1); The IC50 values of c-Met-addicted and c-Met-non-addicted cells against tivantinib, PHA-665752 or crizotinib (S2).
Supplementary Figure Legends from EGFR-Activating Mutations Correlate with a Fanconi Anemia–like Cellular Phenotype That Includes PARP Inhibitor Sensitivity
Authors: Pfäffle Heike N. , Wang Meng , Gheorghiu Liliana , Ferraiolo Natalie , Greninger Patricia , Borgmann Kerstin , Settleman Jeffrey , Benes Cyril H. , Sequist Lecia V. , Zou Lee , Willers Henning
Published: April 2023

PDF file, 51K.
Supplementary Table 2 from The Exomes of the NCI-60 Panel: A Genomic Resource for Cancer Biology and Systems Pharmacology
Authors: Abaan Ogan D. , Polley Eric C. , Davis Sean R. , Zhu Yuelin J. , Bilke Sven , Walker Robert L. , Pineda Marbin , Gindin Yevgeniy , Jiang Yuan , Reinhold William C. , Holbeck Susan L. , Simon Richard M. , Doroshow James H. , Pommier Yves , Meltzer Paul S.
Published: April 2023

XLSX file - 271K, Excel sheet containing additional data for the main text.
Supplementary Figure 3 from c-Src Modulates Estrogen-Induced Stress and Apoptosis in Estrogen-Deprived Breast Cancer Cells
Authors: Fan Ping , Griffith Obi L. , Agboke Fadeke A. , Anur Pavana , Zou Xiaojun , McDaniel Russell E. , Creswell Karen , Kim Sung Hoon , Katzenellenbogen John A. , Gray Joe W. , Jordan V. Craig
Published: April 2023

PDF file - 75K, 3A, The 4-OHT completely blocked E2-induced growth inhibition. MCF-7:5C cells were treated with vehicle (0.1% EtOH), E2 (10-9 mol/L), 4-OHT (10-6 mol/L), E2 (10-9 mol/L) plus 4-OHT(10-6 mol/L) respectively for 7 days. Cells were harvested and total DNA was determined using a DNA fluorescence quantitation kit. P<0.001, ** compared with control. All the data shown were representative of at least three separate experiments with similar results. 3B, Classification of E2-induced apoptosis-related genes selected by RNA-seq in MCF-7:5C cells. MCF-7:5C cells were treated with different compounds as above for 72 hours. Cells were harvested in TRIzol for RNA-seq analysis as in Material and Methods.
Supplementary Figures 1 - 5 from CD95L Cell Surface Cleavage Triggers a Prometastatic Signaling Pathway in Triple-Negative Breast Cancer
Authors: Malleter Marine , Tauzin Sébastien , Bessede Alban , Castellano Rémy , Goubard Armelle , Godey Florence , Levêque Jean , Jézéquel Pascal , Campion Loic , Campone Mario , Ducret Thomas , MacGrogan Gaëtan , Debure Laure , Collette Yves , Vacher Pierre , Legembre Patrick
Published: April 2023

PDF file - 3848K, Figure S1. Pathological doses of cl-CD95L trigger cell migration of TNBC cells. Figure S2. Cl-CD95L induces migration of TNBC cells through a PI3K(p110β)/c-yesdriven signaling pathway. Figure S3. NOX-3-dependent ROS production is instrumental in CD95-mediated cell motility in TNBC cells. Figure S4. Cl-CD95L induces co-localization of CD95 with EGFR. Figure S5. cl-CD95L promotes migration of TNBC cells via EGFR-dependent and EGFindependent signaling pathways.
Supplementary Table 2 from A Classification Model for BRCA2 DNA Binding Domain Missense Variants Based on Homology-Directed Repair Activity
Authors: Guidugli Lucia , Pankratz Vernon S. , Singh Namit , Thompson James , Erding Catherine A. , Engel Christoph , Schmutzler Rita , Domchek Susan , Nathanson Katherine , Radice Paolo , Singer Christian , Tonin Patricia N. , Lindor Noralane M. , Goldgar David E. , Couch Fergus J.
Published: April 2023

PDF file - 58K, Table showing model-based estimates of conditional probabilities in favor or against pathogenicity for VUS based on HDR activity calculated with equal prior probabilities or AGVGD-based prior probabilities for each variant
Supplementary Tables from Constitutive β-Catenin Activation Induces Male-Specific Tumorigenesis in the Bladder Urothelium
Authors: Lin Congxing , Yin Yan , Stemler Kristina , Humphrey Peter , Kibel Adam S. , Mysorekar Indira U. , Ma Liang
Published: April 2023

PDF file, 65K, Supplemental Table 1 B-catenin target genes in the urothelium identified by comparing gene expression of GOF urothelium to that of control urothelia. ; Supplemental Table 2 genes underpinning beta-catenin-induced sexual dimorphic tumorigenesis identified by comparing gene expression of GOF male urothelia to that of female urothelia. ; Supplemental Table 3 Known AR target differentially regulated in male and female GOF bladder urothelia.
Supplementary Figure Legends from Loss of p120-Catenin Induces Metastatic Progression of Breast Cancer by Inducing Anoikis Resistance and Augmenting Growth Factor Receptor Signaling
Authors: Schackmann Ron C.J. , Klarenbeek Sjoerd , Vlug Eva J. , Stelloo Suzan , van Amersfoort Miranda , Tenhagen Milou , Braumuller Tanya M. , Vermeulen Jeroen F. , van der Groep Petra , Peeters Ton , van der Wall Elsken , van Diest Paul J. , Jonkers Jos , Derksen Patrick W.B.
Published: April 2023

PDF - 82K
Supplementary Figure 5 from Loss of p120-Catenin Induces Metastatic Progression of Breast Cancer by Inducing Anoikis Resistance and Augmenting Growth Factor Receptor Signaling
Authors: Schackmann Ron C.J. , Klarenbeek Sjoerd , Vlug Eva J. , Stelloo Suzan , van Amersfoort Miranda , Tenhagen Milou , Braumuller Tanya M. , Vermeulen Jeroen F. , van der Groep Petra , Peeters Ton , van der Wall Elsken , van Diest Paul J. , Jonkers Jos , Derksen Patrick W.B.
Published: April 2023

PDF - 346K, Loss of p120 and subsequent AJ inactivation does not induce autocrine survival pathways or increased EGF binding.
Supplementary Figure 2 from Distinct FAK Activities Determine Progenitor and Mammary Stem Cell Characteristics
Authors: Luo Ming , Zhao Xiaofeng , Chen Song , Liu Suling , Wicha Max S. , Guan Jun-Lin
Published: April 2023

PDF file, 128K, Acinar colony and mammasphere formation for MaECs deleted of FAK in vivo or in vitro.
Legends to Supplementary Figures from A Renewable Tissue Resource of Phenotypically Stable, Biologically and Ethnically Diverse, Patient-Derived Human Breast Cancer Xenograft Models
Authors: Zhang Xiaomei , Claerhout Sofie , Prat Aleix , Dobrolecki Lacey E. , Petrovic Ivana , Lai Qing , Landis Melissa D. , Wiechmann Lisa , Schiff Rachel , Giuliano Mario , Wong Helen , Fuqua Suzanne W. , Contreras Alejandro , Gutierrez Carolina , Huang Jian , Mao Sufeng , Pavlick Anne C. , Froehlich Amber M. , Wu Meng-Fen , Tsimelzon Anna , Hilsenbeck Susan G. , Chen Edward S. , Zuloaga Pavel , Shaw Chad A. , Rimawi Mothaffar F. , Perou Charles M. , Mills Gordon B. , Chang Jenny C. , Lewis Michael T.
Published: April 2023

Legends to Supplementary Figures - PDF file 65K, Legends to supplementary figures
Supplementary Figure 4 from eIF4B Phosphorylation by Pim Kinases Plays a Critical Role in Cellular Transformation by Abl Oncogenes
Authors: Yang Jianling , Wang Jun , Chen Ke , Guo Guijie , Xi Ruijiao , Rothman Paul B. , Whitten Douglas , Zhang Lianfeng , Huang Shile , Chen Ji-Long
Published: April 2023

PDF - 59K, Phosphorylation of eIF4B on Ser422 is regulated by Pim kinase downstream of Jak2 and Stat5 signaling.
Supplementary Figure 3 from eIF4B Phosphorylation by Pim Kinases Plays a Critical Role in Cellular Transformation by Abl Oncogenes
Authors: Yang Jianling , Wang Jun , Chen Ke , Guo Guijie , Xi Ruijiao , Rothman Paul B. , Whitten Douglas , Zhang Lianfeng , Huang Shile , Chen Ji-Long
Published: April 2023

PDF - 76K, Pim-1 and Pim-2 kinases regulate eIF4B phosphorylation in Abl transformants.
Supplementary Figures from Werner Syndrome Helicase Has a Critical Role in DNA Damage Responses in the Absence of a Functional Fanconi Anemia Pathway
Authors: Aggarwal Monika , Banerjee Taraswi , Sommers Joshua A. , Iannascoli Chiara , Pichierri Pietro , Shoemaker Robert H. , Brosh Robert M.
Published: April 2023

PDF file, 1010K, Chemical structures of structurally related analogs of the previously identified parent compound NSC 19630 (S1); Effect of NSC 617145 on WRN catalytic functions and DNA unwinding by other helicases (S2); Effect of selected small molecules structurally related to NSC 19630 on HeLa cell proliferation (S3); NSC 617145 inhibits cell proliferation in a WRN-dependent manner (S4); Effect of NSC 617145 on WRN-depleted cells expressing ectopic WRN protein that is active or inactive as for ATPase/helicase activity (S5); Specificity of WRN helicase inhibition by NSC 617145 (S6); NSC 617145 induces DNA damage (S7); NSC 617145 induces apoptosis when WRN is present (S8); Elevated PCNA staining of NSC 617145-treated cells is WRNdependent (S9); Effect of NSC 617145 exposure on cell cycle (S10); NSC 617145 exposure does not sensitize HeLa, FA-A, or FA-D2 cells to hydroxyurea (S11); WRN depletion does not affect MMC sensitivity of FA-D2 mutant cells (S12); Western blot analysis of ATM activation in FA-D2 mutant cells (S13).
Supplementary Figure 2 from Novel DNA Damage Checkpoints Mediating Cell Death Induced by the NEDD8-Activating Enzyme Inhibitor MLN4924
Authors: Blank Jonathan L. , Liu Xiaozhen J. , Cosmopoulos Katherine , Bouck David C. , Garcia Khristofer , Bernard Hugues , Tayber Olga , Hather Greg , Liu Ray , Narayanan Usha , Milhollen Michael A. , Lightcap Eric S.
Published: April 2023

PDF file - 337K, Analysis of flow cytometry results of the effect of vehicle (DMSO) or 3 muM MLN4924 for 24 h on multiple cell lines
Supplementary Figure 4 from SOX10 Ablation Arrests Cell Cycle, Induces Senescence, and Suppresses Melanomagenesis
Authors: Cronin Julia C. , Watkins-Chow Dawn E. , Incao Art , Hasskamp Joanne H. , Schönewolf Nicola , Aoude Lauren G. , Hayward Nicholas K. , Bastian Boris C. , Dummer Reinhard , Loftus Stacie K. , Pavan William J.
Published: April 2023

PDF file, 164K, KitlacZ and Mitfvga are not sufficient genetic alterations to suppress melanoma in Grm1Tg mice.
Supplementary Figure 5 from Complex Tumor Genomes Inferred from Single Circulating Tumor Cells by Array-CGH and Next-Generation Sequencing
Authors: Heitzer Ellen , Auer Martina , Gasch Christin , Pichler Martin , Ulz Peter , Hoffmann Eva Maria , Lax Sigurd , Waldispuehl-Geigl Julie , Mauermann Oliver , Lackner Carolin , Höfler Gerald , Eisner Florian , Sill Heinz , Samonigg Hellmut , Pantel Klaus , Riethdorf Sabine , Bauernhofer Thomas , Geigl Jochen B. , Speicher Michael R.
Published: April 2023

PDF file - 346K, Analysis of CTC03 of patient #22: The array-CGH ratio profile demonstrates losses on chromosomes 3, 4, 5, 8p, and 18 and gains on chromosomes 7p, 17q, and 20.
Supplementary Figure 4 from Complex Tumor Genomes Inferred from Single Circulating Tumor Cells by Array-CGH and Next-Generation Sequencing
Authors: Heitzer Ellen , Auer Martina , Gasch Christin , Pichler Martin , Ulz Peter , Hoffmann Eva Maria , Lax Sigurd , Waldispuehl-Geigl Julie , Mauermann Oliver , Lackner Carolin , Höfler Gerald , Eisner Florian , Sill Heinz , Samonigg Hellmut , Pantel Klaus , Riethdorf Sabine , Bauernhofer Thomas , Geigl Jochen B. , Speicher Michael R.
Published: April 2023

PDF file - 1362K, Evaluation of available material from patient #38. (a-b) Array CGH profiles of the primary tumor (a) and liver metastasis (b).
Data Supplement from Chromosomal Instability Selects Gene Copy-Number Variants Encoding Core Regulators of Proliferation in ER+ Breast Cancer
Authors: Endesfelder David , Burrell Rebecca A. , Kanu Nnennaya , McGranahan Nicholas , Howell Mike , Parker Peter J. , Downward Julian , Swanton Charles , Kschischo Maik
Published: April 2023

Supplementary Table S1: Genes that impair cell viability (Z-Score < -2) in at least 3/5 cell lines (PC9 (lung), RCC4 (kidney), HCT116 (colon), MCF-10A (breast) and HT1080 (fibrosarcoma)) in RNAi screens and their Z-scores. These genes were regarded as proliferation genes. Supplementary Table S2: GO Term Enrichment for Proliferation Genes (RNAi Screens) found in Supplementary Table S1. Supplementary Table S3: Candidate core regulators prior to CONEXIC analysis. Supplementary Table S4: GO Term Enrichment of Top 30 Key Regulators. Supplementary Table S5: Top 50 GO Terms Enriched for Module Genes Belonging to Core Regulators from Table 1. P-Values were derived by Fishers Exact Test. The GO analysis for each core regulator module was done independently of the other core regulator modules. Supplementary Table S6: The amplified core regulators TPX2, AURKA, UBE2C, EXO1, MYBL2, TPT1, KIF14 and UBE2T are also members of at least one breast cancer prognostic signature.
Supplementary Material 2 from Androgen Glucuronidation: An Unexpected Target for Androgen Deprivation Therapy, with Prognosis and Diagnostic Implications
Authors: Grosse Laurent , Pâquet Sophie , Caron Patrick , Fazli Ladan , Rennie Paul S. , Bélanger Alain , Barbier Olivier
Published: April 2023

PDF file - 10741K, Supplementary material 2: Representative examples of immunoexpression obtained after incubation of prostate tissue microarrays with the anti-UGT2B15, anti-UGT2B17 or anti-vimentin antibodies.
Supplementary Figures 1 - 5 from Differential Contributions of STAT5A and STAT5B to Stress Protection and Tyrosine Kinase Inhibitor Resistance of Chronic Myeloid Leukemia Stem/Progenitor Cells
Authors: Casetti Luana , Martin-Lannerée Séverine , Najjar Imen , Plo Isabelle , Augé Sylvie , Roy Lydia , Chomel Jean-Claude , Lauret Evelyne , Turhan Ali G. , Dusanter-Fourt Isabelle
Published: April 2023

PDF file - 589K, shS5A, shS5B and shS5A/B differentially affect STAT5 expression in CML and normal stem/progenitor cells (S1); Characteristics of CML cells following addition of the indicated shRNA encoding lentiviral particles (S2); shS5A enhances ROS which depends on NADPH oxidase activity in CML cells (S3); Characteristics of IM-sensitive and -resistant CML cells (S4); Expression of STAT5A and STAT5B mRNA in normal and CML CD34+ stem/progenitor cells (S5).
Supplementary Figure 1 from A CD90+ Tumor-Initiating Cell Population with an Aggressive Signature and Metastatic Capacity in Esophageal Cancer
Authors: Tang Kwan Ho , Dai Yong Dong , Tong Man , Chan Yuen Piu , Kwan Pak Shing , Fu Li , Qin Yan Ru , Tsao Sai Wah , Lung Hong Lok , Lung Maria L. , Tong Daniel K. , Law Simon , Chan Kwok Wah , Ma Stephanie , Guan Xin Yuan
Published: April 2023

PDF file - 490K, Supplemental Figure 1. A significantly deregulated network of genes in CD90+ esophageal T-ICs identified by genome-wide expression profiling and Ingenuity Pathway Analysis (IPA).
Supplementary Figure S5 from mTOR Complex 2 Is Involved in Regulation of Cbl-Dependent c-FLIP Degradation and Sensitivity of TRAIL-Induced Apoptosis
Authors: Zhao Liqun , Yue Ping , Khuri Fadlo R. , Sun Shi-Yong
Published: April 2023

Supplementary Figure S5 PDF file - 172K, siRNA-mediated knockdown of rictor, but not raptor, sensitizes cells to TRAIL-induced apoptosis
Supplementary Methods from Senescent Fibroblasts in Melanoma Initiation and Progression: An Integrated Theoretical, Experimental, and Clinical Approach
Authors: Kim Eunjung , Rebecca Vito , Fedorenko Inna V. , Messina Jane L. , Mathew Rahel , Maria-Engler Silvya S. , Basanta David , Smalley Keiran S.M. , Anderson Alexander R.A.
Published: April 2023

PDF file - 719K
Supplementary Figure S1 from mTOR Complex 2 Is Involved in Regulation of Cbl-Dependent c-FLIP Degradation and Sensitivity of TRAIL-Induced Apoptosis
Authors: Zhao Liqun , Yue Ping , Khuri Fadlo R. , Sun Shi-Yong
Published: April 2023

Supplementary Figure S1 PDF file - 69K,Combination Indexes (CIs) for interaction between PP242 and TRAIL in NSCLC cells
Supplementary Figure Legends from Transient Antiangiogenic Treatment Improves Delivery of Cytotoxic Compounds and Therapeutic Outcome in Lung Cancer
Authors: Chatterjee Sampurna , Wieczorek Caroline , Schöttle Jakob , Siobal Maike , Hinze Yvonne , Franz Thomas , Florin Alexandra , Adamczak Joanna , Heukamp Lukas C. , Neumaier Bernd , Ullrich Roland T.
Published: April 2023

PDF file - 66KB
Supplementary Figure 4 from Transient Antiangiogenic Treatment Improves Delivery of Cytotoxic Compounds and Therapeutic Outcome in Lung Cancer
Authors: Chatterjee Sampurna , Wieczorek Caroline , Schöttle Jakob , Siobal Maike , Hinze Yvonne , Franz Thomas , Florin Alexandra , Adamczak Joanna , Heukamp Lukas C. , Neumaier Bernd , Ullrich Roland T.
Published: April 2023

PDF file - 1341KB, Pericyte coverage and tumor cell proliferation.
Supplementary Tables 1 and 2 from Tumor Hypoxia Does Not Drive Differentiation of Tumor-Associated Macrophages but Rather Fine-Tunes the M2-like Macrophage Population
Authors: Laoui Damya , Van Overmeire Eva , Di Conza Giusy , Aldeni Chiara , Keirsse Jiri , Morias Yannick , Movahedi Kiavash , Houbracken Isabelle , Schouppe Elio , Elkrim Yvon , Karroum Oussama , Jordan Bénédicte , Carmeliet Peter , Gysemans Conny , De Baetselier Patrick , Mazzone Massimiliano , Van Ginderachter Jo A.
Published: April 2023

PDf - 36K, List of antibodies (S1); List of gene specific primers (S2).
Supplementary Video 10 from Endogenous Two-Photon Fluorescence Imaging Elucidates Metabolic Changes Related to Enhanced Glycolysis and Glutamine Consumption in Precancerous Epithelial Tissues
Authors: Varone Antonio , Xylas Joanna , Quinn Kyle P. , Pouli Dimitra , Sridharan Gautham , McLaughlin-Drubin Margaret E. , Alonzo Carlo , Lee Kyongbum , Münger Karl , Georgakoudi Irene
Published: April 2023

AVI file - 1258KB, Representative 3D RENDERING E6 EETE.
Supplementary Methods, Figure Legends, Video Legends from Endogenous Two-Photon Fluorescence Imaging Elucidates Metabolic Changes Related to Enhanced Glycolysis and Glutamine Consumption in Precancerous Epithelial Tissues
Authors: Varone Antonio , Xylas Joanna , Quinn Kyle P. , Pouli Dimitra , Sridharan Gautham , McLaughlin-Drubin Margaret E. , Alonzo Carlo , Lee Kyongbum , Münger Karl , Georgakoudi Irene
Published: April 2023

PDF file - 147KB
Supplementary Figure Legends, Figures 1 - 6 from Endothelial Cell-Secreted EGF Induces Epithelial to Mesenchymal Transition and Endows Head and Neck Cancer Cells with Stem-like Phenotype
Authors: Zhang Zhaocheng , Dong Zhihong , Lauxen Isabel S. , Filho Manoel Sant'Ana , Nör Jacques E.
Published: April 2023

PDF file - 524KB, Supplementary Figure 1. Endothelial cell-secreted EGF induces phenotypic changes consistent with EMT in head and neck squamous cell carcinoma cells. Supplementary Figure 2. Endothelial cell-secreted factors enhance the motility of HNSCC. Supplementary Figure 3. Endothelial cell-secreted factors activate STAT3, Akt and ERK signaling. Supplementary Figure 4. Endothelial cell-secreted EGF induces Snail expression via PI3K/Akt signaling. Supplementary Figure 5. EGF enhances the fraction of cancer stem-like cells. Supplementary Figure 6. Endothelial cell-secreted EGF dose not increase blood vessel density in tumors in vivo.
Supplementary Tables from Childhood Height and Body Mass Index Were Associated with Risk of Adult Thyroid Cancer in a Large Cohort Study
Authors: Kitahara Cari M. , Gamborg Michael , Berrington de González Amy , Sørensen Thorkild I.A. , Baker Jennifer L.
Published: April 2023

PDF file 75K, Supplementary Table 1. Hazard ratios and 95% confidence intervals for papillary and follicular thyroid cancer per 1-standard deviation score difference in height and BMI at each age from 7-13 years Supplementary Table 2. Hazard ratios and 95% confidence intervals for total thyroid cancer per 1-standard deviation score difference in height at each age from 7-13 years, by age at diagnosis Supplementary Table 3. Hazard ratios and 95% confidence intervals for total thyroid cancer per 1-standard deviation score difference in BMI at each age from 7-13 years, by age at diagnosis Supplementary Table 4. Hazard ratios and 95% confidence intervals for total thyroid cancer per 1-standard deviation score difference in height and BMI at each age from 7-13 years, mutually adjusted Supplementary Table 5. Hazard ratios and 95% confidence intervals for total thyroid cancer per 1-standard deviation score difference in height and BMI at each age from 7-13 years, restricted to participants with data on birth weight Supplementary Table 6. Hazard ratios of thyroid cancer by quintiles of change in height SDS between ages 7 and 13 years Supplementary Table 7. Hazard ratios of thyroid cancer by quintiles of change in BMI SDS between ages 7 and 13 years
Supplementary Figure 1 from Natural Human Plasmacytoid Dendritic Cells Induce Antigen-Specific T-Cell Responses in Melanoma Patients
Authors: Tel Jurjen , Aarntzen Erik H.J.G. , Baba Tetsuro , Schreibelt Gerty , Schulte Barbara M. , Benitez-Ribas Daniel , Boerman Otto C. , Croockewit Sandra , Oyen Wim J.G. , van Rossum Michelle , Winkels Gregor , Coulie Pierre G. , Punt Cornelis J.A. , Figdor Carl G. , de Vries I. Jolanda M.
Published: April 2023

Supplementary Figure 1 PDF file - 34K, Supplementary Figure 1 CliniMACS-based pDC isolation is feasible
Supplementary Figure 5 from TGF-β Mediates Homing of Bone Marrow–Derived Human Mesenchymal Stem Cells to Glioma Stem Cells
Authors: Shinojima Naoki , Hossain Anwar , Takezaki Tatsuya , Fueyo Juan , Gumin Joy , Gao Feng , Nwajei Felix , Marini Frank C. , Andreeff Michael , Kuratsu Jun-Ichi , Lang Frederick F.
Published: April 2023

PDF file - 2556K, TGFβ levels do not alter tumor vascularity or tumor size.
Supplementary Figure 3 from FOXC2 Expression Links Epithelial–Mesenchymal Transition and Stem Cell Properties in Breast Cancer
Authors: Hollier Brett G. , Tinnirello Agata A. , Werden Steven J. , Evans Kurt W. , Taube Joseph H. , Sarkar Tapasree Roy , Sphyris Nathalie , Shariati Maryam , Kumar Sreedevi V. , Battula Venkata L. , Herschkowitz Jason I. , Guerra Rudy , Chang Jeffrey T. , Miura Naoyuki , Rosen Jeffrey M. , Mani Sendurai A.
Published: April 2023

Supplementary Figure 3 PDF File - 326K, Attenuation of FOXC2 expression leads to reduced levels of PDGFR- �. (a) Immunofluorescene staining for PDGFR-� (red) detected with Alexa Fluor 548 anti-mouse secondary antibody in HMLE, HMLE-Snail-shCntrl and HMLE-Snail-shFOXC2 cells. Nuclei were counterstained with DAPI and overlayed images are shown.Scale bar indicates 100 �m. (b) FACS analysis of PDGFR-� cell surface expression using anti- PDGFR-�-PE antibody in cells described in (a). The histogram represents the intensity of PE signal in the FL2 detector on the x-axis
Supplementary Figure 2 from TGF-β Mediates Homing of Bone Marrow–Derived Human Mesenchymal Stem Cells to Glioma Stem Cells
Authors: Shinojima Naoki , Hossain Anwar , Takezaki Tatsuya , Fueyo Juan , Gumin Joy , Gao Feng , Nwajei Felix , Marini Frank C. , Andreeff Michael , Kuratsu Jun-Ichi , Lang Frederick F.
Published: April 2023

PDF file - 1271K, Proliferation effects of knocking down TGFβRII or CD105 in BM-hMSCs.
Supplementary Tables 1 - 4 from p53 Is Positively Regulated by miR-542-3p
Authors: Wang Yemin , Huang Jen-Wei , Castella Maria , Huntsman David George , Taniguchi Toshiyasu
Published: April 2023

PDF file - 117KB, Summary of miRNA mimic library screen to identify miRNAs that regulate p53 expression (S1). Top Canonical Pathways affected by miR-542-3p in U2OS cells (S2). Components of p53 signaling pathway that were significantly affected by miR-542-3p in U2OS cells (S3). Components of ribosome that were modulated by miR-542-3p in U2OS cells (S4).
Supplementary Figures 1 - 9 from p53 Is Positively Regulated by miR-542-3p
Authors: Wang Yemin , Huang Jen-Wei , Castella Maria , Huntsman David George , Taniguchi Toshiyasu
Published: April 2023

PDF file - 574KB, Precursor of miR-542-3p induces p53 expression (S1). MiR-542-3p has no effect on p53 mRNA level (S2). Effects of miR-542-3p on p53 expression in multiple cell lines (S3). MiR-542-3p has no effect on expression levels of various modulators of p53 degradation (S4). Actinomycin D induces p53 expression (S5). Amplification of RPS23 transcript (S6). Effects of miR-542-3p and siRPS23 on cell growth (S7). MiR-542-3p Inhibits cell growth independent of RPS23 (S8). miR-542-3p inhibits cell growth independent of p53 (S9).
Supplementary Table S3 from MYC Regulation of CHK1 and CHK2 Promotes Radioresistance in a Stem Cell-like Population of Nasopharyngeal Carcinoma Cells
Authors: Wang Wen-Jun , Wu Si-Pei , Liu Jia-Bin , Shi Yong-Sheng , Huang Xue , Zhang Qian-Bing , Yao Kai-Tai
Published: April 2023

XLS file - 34K,Binding sites (c-MYCBSs) within the 2000bp promoter upstream of the CHK1 and CHK2 genes
Supplementary Figure 3 from Myeloid-Specific Expression of Ron Receptor Kinase Promotes Prostate Tumor Growth
Authors: Gurusamy Devikala , Gray Jerilyn K. , Pathrose Peterson , Kulkarni Rishikesh M. , Finkleman Fred D. , Waltz Susan E.
Published: April 2023

PDF file - 138K, qRT-PCR analysis of cytokines in the tumor proper and Ron expression in purified cell populations. For Review and Publication Both.
Supplementary Figure Legend and Tables 2 - 3 from Characterization of Torin2, an ATP-Competitive Inhibitor of mTOR, ATM, and ATR
Authors: Liu Qingsong , Xu Chunxiao , Kirubakaran Sivapriya , Zhang Xin , Hur Wooyoung , Liu Yan , Kwiatkowski Nicholas P. , Wang Jinhua , Westover Kenneth D. , Gao Peng , Ercan Dalia , Niepel Mario , Thoreen Carson C. , Kang Seong A. , Patricelli Matthew P. , Wang Yuchuan , Tupper Tanya , Altabef Abigail , Kawamura Hidemasa , Held Kathryn D. , Chou Danny M. , Elledge Stephen J. , Janne Pasi A. , Wong Kwok-Kin , Sabatini David M. , Gray Nathanael S.
Published: April 2023

PDF file - 69K
Supplementary Figure 3 from Automated Tracking of Nanoparticle-labeled Melanoma Cells Improves the Predictive Power of a Brain Metastasis Model
Authors: Sundstrøm Terje , Daphu Inderjit , Wendelbo Ingvild , Hodneland Erlend , Lundervold Arvid , Immervoll Heike , Skaftnesmo Kai Ove , Babic Michal , Jendelova Pavla , Sykova Eva , Lund-Johansen Morten , Bjerkvig Rolf , Thorsen Frits
Published: April 2023

PDF file - 241K, SPIONs do not influence cell migration and growth in vitro
Supplementary Table 1 from MDM2 Small-Molecule Antagonist RG7112 Activates p53 Signaling and Regresses Human Tumors in Preclinical Cancer Models
Authors: Tovar Christian , Graves Bradford , Packman Kathryn , Filipovic Zoran , Xia Brian Higgins Mingxuan , Tardell Christine , Garrido Rosario , Lee Edmund , Kolinsky Kenneth , To Kwong-Him , Linn Michael , Podlaski Frank , Wovkulich Peter , Vu Binh , Vassilev Lyubomir T.
Published: April 2023

PDF file - 12K, Antitumor activity of RG7112 against a panel of solid tumor cells.
Supplementary Materials and Methods and Figure Legends from Therapeutic PD-1 Pathway Blockade Augments with Other Modalities of Immunotherapy T-Cell Function to Prevent Immune Decline in Ovarian Cancer
Authors: Duraiswamy Jaikumar , Freeman Gordon J. , Coukos George
Published: April 2023

PDF file, 122K.
Supplementary Figure 8 from Therapeutic PD-1 Pathway Blockade Augments with Other Modalities of Immunotherapy T-Cell Function to Prevent Immune Decline in Ovarian Cancer
Authors: Duraiswamy Jaikumar , Freeman Gordon J. , Coukos George
Published: April 2023

PDF file, 20K, Combination therapy increases ovarian tumor antigen (mesothelin) specific inflammatory cytokine production by ID8 TILs.
Supplementary Methods, Legends for Table 1, Figures 1-6, Movies 1-2 from Definition of Molecular Determinants of Prostate Cancer Cell Bone Extravasation
Authors: Barthel Steven R. , Hays Danielle L. , Yazawa Erika M. , Opperman Matthew , Walley Kempland C. , Nimrichter Leonardo , Burdick Monica M. , Gillard Bryan M. , Moser Michael T. , Pantel Klaus , Foster Barbara A. , Pienta Kenneth J. , Dimitroff Charles J.
Published: April 2023

PDF file - 275K
Supplementary Figure 3 from Definition of Molecular Determinants of Prostate Cancer Cell Bone Extravasation
Authors: Barthel Steven R. , Hays Danielle L. , Yazawa Erika M. , Opperman Matthew , Walley Kempland C. , Nimrichter Leonardo , Burdick Monica M. , Gillard Bryan M. , Moser Michael T. , Pantel Klaus , Foster Barbara A. , Pienta Kenneth J. , Dimitroff Charles J.
Published: April 2023

PDF file - 137K, Modulating FT expression does not alter PCa cell integrin expression or function
Supplementary Figures 1 - 11 from An Inducible Hepatocellular Carcinoma Model for Preclinical Evaluation of Antiangiogenic Therapy in Adult Mice
Authors: Runge Anja , Hu Junhao , Wieland Matthias , Bergeest Jan-Philip , Mogler Carolin , Neumann André , Géraud Cyrill , Arnold Bernd , Rohr Karl , Komljenovic Dorde , Schirmacher Peter , Goerdt Sergij , Augustin Hellmut G.
Published: April 2023

PDF file - 8221K, Supplementary Figure S1: Kinetics of tumorigenic transformation, Supplementary Figure S2: Kinetics of VEGF expression. Supplementary Figure S3: Functional liver tumor vasculature. Supplementary Figure S4: Side effects in long-term Sorafenib-treated iAST mice. Supplementary Figure S5: VEGF-A expression after Sorafenib treatment Supplementary Figure S6: Necrosis and hypoxia in Sorafenib-treated livers. Supplementary Figure S7: Sinusoidal marker expression upon Sorafenib treatment. Supplementary Figure S8: Vascular remodeling upon Sorafenib treatment. Supplementary Figure S9: Microarray data analysis. Supplementary Figure S10: Regained proliferative potential after LT-Sorafenib administration. Supplementary Figure S11: Stable weight in Sorafenib-treated mice.
Supplementary Figure 6 from Thyroid Hormone Regulation of miR-21 Enhances Migration and Invasion of Hepatoma
Authors: Huang Ya-Hui , Lin Yang-Hsiang , Chi Hsiang-Cheng , Liao Chen-Hsin , Liao Chia-Jung , Wu Sheng-Ming , Chen Cheng-Yi , Tseng Yi-Hsin , Tsai Chung-Ying , Lin Sheng-Yen , Hung Yu-Ting , Wang Chih-Jen , Lin Crystal D. , Lin Kwang-Huei
Published: April 2023

PDF - 179K, MSH2 is a miR-21 target downregulated by T3.
Supplementary Table 1 from The Insulin Receptor Negatively Regulates the Action of Pseudomonas Toxin-Based Immunotoxins and Native Pseudomonas Toxin
Authors: Liu Xiu Fen , FitzGerald David J. , Pastan Ira
Published: April 2023

PDF file - 93K, Summary of the results of SS1P toxicity after IR knock down or addition of inhibitors in KB31 cells.
Supplementary Figure S5 from Adjuvants That Improve the Ratio of Antigen-Specific Effector to Regulatory T Cells Enhance Tumor Immunity
Authors: Perret Rachel , Sierro Sophie R. , Botelho Natalia K. , Corgnac Stéphanie , Donda Alena , Romero Pedro
Published: April 2023

Supplementary Figure S5. Cytokine production by antigen-specific T cells at the peak of the effector response
Supplementary Figure S4 from A Multifunctional Chimeric Chaperone Serves as a Novel Immune Modulator Inducing Therapeutic Antitumor Immunity
Authors: Yu Xiaofei , Guo Chunqing , Yi Huanfa , Qian Jie , Fisher Paul B. , Subjeck John R. , Wang Xiang-Yang
Published: April 2023

Supplementary Figure S4 PDF file - 86K, Ad.Flagrp170 therapy augments a potent immune response against B16 melanoma
Supplementary Figure and Movie Legend from Integrin-Free Tetraspanin CD151 Can Inhibit Tumor Cell Motility upon Clustering and Is a Clinical Indicator of Prostate Cancer Progression
Authors: Palmer Trenis D. , Martínez Carlos H. , Vasquez Catalina , Hebron Katie E. , Jones-Paris Celestial , Arnold Shanna A. , Chan Susanne M. , Chalasani Venu , Gomez-Lemus Jose A. , Williams Andrew K. , Chin Joseph L. , Giannico Giovanna A. , Ketova Tatiana , Lewis John D. , Zijlstra Andries
Published: April 2023

PDf - 92K, Legends for Supplementary Figures S1-S8 as well as Supplementary Movie S1.
Supplementary Table 1 from IFN-γ–Mediated Downregulation of LXA4 Is Necessary for the Maintenance of Nonresolving Inflammation and Papilloma Persistence
Authors: Wang Chunhui , Xiao Mingjie , Liu Xiaoman , Ni Chen , Liu Jianhong , Erben Ulrike , Qin Zhihai
Published: April 2023

Supplementary Table 1 PDF file - 1931K, Neutralization of IFN� did not have a significant influence on carcinoma development
Supplementary Figure S4 from IFN-γ–Mediated Downregulation of LXA4 Is Necessary for the Maintenance of Nonresolving Inflammation and Papilloma Persistence
Authors: Wang Chunhui , Xiao Mingjie , Liu Xiaoman , Ni Chen , Liu Jianhong , Erben Ulrike , Qin Zhihai
Published: April 2023

Supplementary Figure S4 PDF file - 1223K, CD4+ cell deficiency promoted papilloma regression
Supplementary Figure S3 from IFN-γ–Mediated Downregulation of LXA4 Is Necessary for the Maintenance of Nonresolving Inflammation and Papilloma Persistence
Authors: Wang Chunhui , Xiao Mingjie , Liu Xiaoman , Ni Chen , Liu Jianhong , Erben Ulrike , Qin Zhihai
Published: April 2023

Supplementary Figure S3 PDF file - 433K, Anti-IFN� and/or LXA4 treatment accelerated papilloma regression
Supplementary Figure S1 from IFN-γ–Mediated Downregulation of LXA4 Is Necessary for the Maintenance of Nonresolving Inflammation and Papilloma Persistence
Authors: Wang Chunhui , Xiao Mingjie , Liu Xiaoman , Ni Chen , Liu Jianhong , Erben Ulrike , Qin Zhihai
Published: April 2023

Supplementary Figure S1 PDF file - 1841K, The LXA4 used in our experiments was structurally integrated
Supplementary Figure 3 from Inhibition of CSF-1 Receptor Improves the Antitumor Efficacy of Adoptive Cell Transfer Immunotherapy
Authors: Mok Stephen , Koya Richard C. , Tsui Christopher , Xu Jingying , Robert Lídia , Wu Lily , Graeber Thomas G. , West Brian L. , Bollag Gideon , Ribas Antoni
Published: April 2023

PDF file - 68K, Gating strategy for the studies of myeloid cells.
Supplementary Figure 2 from Inhibition of CSF-1 Receptor Improves the Antitumor Efficacy of Adoptive Cell Transfer Immunotherapy
Authors: Mok Stephen , Koya Richard C. , Tsui Christopher , Xu Jingying , Robert Lídia , Wu Lily , Graeber Thomas G. , West Brian L. , Bollag Gideon , Ribas Antoni
Published: April 2023

PDF file - 59K, Combined anti-tumor activity of adoptive cell transfer (ACT) immunotherapy and PLX3397 in SM1 and B16 murine melanoma.
Supplementary Methods from Multimodal Elucidation of Choline Metabolism in a Murine Glioma Model Using Magnetic Resonance Spectroscopy and 11C-Choline Positron Emission Tomography
Authors: Wehrl Hans F. , Schwab Julian , Hasenbach Kathy , Reischl Gerald , Tabatabai Ghazaleh , Quintanilla-Martinez Leticia , Jiru Filip , Chughtai Kamila , Kiss Andras , Cay Funda , Bukala Daniel , Heeren Ron M.A. , Pichler Bernd J. , Sauter Alexander W.
Published: April 2023

PDF file - 121K
Supplementary Figure 1 from Inherited Variation in miR-290 Expression Suppresses Breast Cancer Progression by Targeting the Metastasis Susceptibility Gene Arid4b
Authors: Goldberger Natalie , Walker Renard C. , Kim Chang Hee , Winter Scott , Hunter Kent W.
Published: April 2023

PDF file - 455K, Latency, tumor burden and metastatic index values in all 18 AKXD RI strains.
Supplementary Table 3 from Global Transcriptome Analysis of Formalin-Fixed Prostate Cancer Specimens Identifies Biomarkers of Disease Recurrence
Authors: Long Qi , Xu Jianpeng , Osunkoya Adeboye O. , Sannigrahi Soma , Johnson Brent A. , Zhou Wei , Gillespie Theresa , Park Jong Y. , Nam Robert K. , Sugar Linda , Stanimirovic Aleksandra , Seth Arun K. , Petros John A. , Moreno Carlos S.
Published: April 2023

XLSX file - 9K, Summary of sequencing statistics from RNAseq analysis of 106 FFPE RNA samples.
Supplementary Figure Legend from Polo-like Kinase 1: A Potential Therapeutic Option in Combination with Conventional Chemotherapy for the Management of Patients with Triple-Negative Breast Cancer
Authors: Maire Virginie , Némati Fariba , Richardson Marion , Vincent-Salomon Anne , Tesson Bruno , Rigaill Guillem , Gravier Eléonore , Marty-Prouvost Bérengère , De Koning Leanne , Lang Guillaume , Gentien David , Dumont Aurélie , Barillot Emmanuel , Marangoni Elisabetta , Decaudin Didier , Roman-Roman Sergio , Pierré Alain , Cruzalegui Francisco , Depil Stéphane , Tucker Gordon C. , Dubois Thierry
Published: April 2023

PDF file - 66K
Supplementary Tables 1 - 5 from Selection of Personalized Patient Therapy through the Use of Knowledge-Based Computational Models That Identify Tumor-Driving Signal Transduction Pathways
Authors: Verhaegh Wim , van Ooijen Henk , Inda Márcia A. , Hatzis Pantelis , Versteeg Rogier , Smid Marcel , Martens John , Foekens John , van de Wiel Paul , Clevers Hans , van de Stolpe Anja
Published: April 2023

PDF file - 131KB, Wnt target genes and probesets (S1). ER target genes and probesets (S2). Used datasets (S3). Variation in predicted probability of pathway activity between and within cell lines, assessed on dataset E-MTAB-37 (S4). Gene set enrichment analysis results on normal colon samples versus colon adenoma from GSE8671 (S5).
Supplementary Figure 2 from Homing of Human B Cells to Lymphoid Organs and B-Cell Lymphoma Engraftment Are Controlled by Cell Adhesion Molecule JAM-C
Authors: Doñate Carmen , Ody Christiane , McKee Thomas , Ruault-Jungblut Sylvie , Fischer Nicolas , Ropraz Patricia , Imhof Beat A. , Matthes Thomas
Published: April 2023

PDF file - 6982K, Analysis of human B cell migration to lymphoid organs of NOD/SCID mice
Supplementary Table 1 from Combination Therapy Targeting the Chk1 and Wee1 Kinases Shows Therapeutic Efficacy in Neuroblastoma
Authors: Russell Mike R. , Levin Kirill , Rader JulieAnn , Belcastro Lili , Li Yimei , Martinez Daniel , Pawel Bruce , Shumway Stuart D. , Maris John M. , Cole Kristina A.
Published: April 2023

PDF file - 42K, Therapies targeting Chk1/Wee1 in combination with chemotherapy demonstrates synergy in most neuroblastoma cells. Ten neuroblastoma cell lines were tested for synergistic interactions between MK-1775 or MK-8776 in combination with either SN-38 (irinotecan) or gemcitabine. Combination indices were determined by increasing concentrations of both drug simultaneously (based on multiples of each drugs individual IC50), utilizing the Chou-Talalay method. The majority of neuroblastoma lines demonstrated synergy (denoted by a CI value < 0.7) in combination with chemotherapy, and particularly in the MK-1775 + MK-8776 combination group
Supplementary Figure Legends 1-4, Table Legend 1 from Combination Therapy Targeting the Chk1 and Wee1 Kinases Shows Therapeutic Efficacy in Neuroblastoma
Authors: Russell Mike R. , Levin Kirill , Rader JulieAnn , Belcastro Lili , Li Yimei , Martinez Daniel , Pawel Bruce , Shumway Stuart D. , Maris John M. , Cole Kristina A.
Published: April 2023

PDF file - 55K