bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of banana on ameliorating hyperlipidemia and cardiomyopathy in diabetic SHR
Authors: Lin Hui-Li , Pan Peter , Su Hui-Chen , Chen Ya-Mei , Tseng Yu-Hsiu , Hao Chi-Long , Keng Chih-Yueh , Shen Kuo-Ping
Published: February 2024

Background: We have shown that bananas could improve diabetes mellitus (DM) and related vascular dysfunction. Continuing the previous results, this study aims to find out the anti-DM-induced hyperlipidemia and cardiac dysfunction effect of bananas. This study selected spontaneously hypertensive rats (SHR) as the experimental subjects and divided them into 3 groups.
Method: The control group (n=8) was fed standard chew. The type 2 diabetes group (T2D group; n=8) was intraperitoneally injected with streptozotocin and nicotinamide (STZ/NA) and fed a high-fat diet (HFD). Another group was intraperitoneally injected with STZ/NA and fed a HFD and the carbohydrate was exchanged with banana powder (BA) (T2D/BA group).
Results: After four weeks, hyperlipidemia, hyperuricemia, and higher levels of GPT, IL-6, TNF-α, ox-LDL, and MDA occurred in the T2D group. Moreover, DM deteriorated the related lipid synthesis and metabolism proteins and also worsened the regulating cardiac fibrosis, hypertrophy-related proteins, and as well as inflammatory signaling proteins. In the T2D/BA group, except GPT, the above biochemical parameters affected by DM were all improved.
Conclusions: We concluded that BA ameliorated DM-induced hyperlipidemia and worsened cardiomyopathy by improving lipid homeostasis, reversing cardiac dysfunction, and inhibiting inflammation. Together, we suggest that bananas may serve as an effective dietary intervention for the management of metabolic syndrome.
An insight into the epidemiology of foodborne zoonotic fascioliasis in small ruminants in northwestern region of Bangladesh
Authors: TALUKDER MD Hasanuzzaman , Ahmed Nurnabi , ISLAM Md Nuruzzaman , ISLAM Md Rafiul , ROY Babul Chandra , Akter Shirin
Published: February 2024

Fascioliasis is one of the most common foodborne zoonotic infection of ruminants in Bangladesh. To estimate the prevalence and associated risk factors of fascioliasis and extent of liver damage, 825 livers of sheep and goats were randomly inspected during onsite slaughterhouse visiting in Naogaon, Natore, Rajshahi and Joypurhat districts. The overall prevalence of fascioliasis was 25.09% and significantly (P = 0.008) higher in goats (26.11%) than sheep (24.00%). During gross inspection, Fasciolainfected livers were increased in size, fibrosed, fatty, multiple white or reddish necrotic foci on the parietal surface, hard to cut, calcified, and numerous mature and immature flukes were also observed. In histoarchitecture, inflammatory cell infiltration in the hepatic parenchyma and periportal area, fibrous connective tissue proliferation around necrotic area, hyperplastic bile duct, congestion, and primary biliary cirrhosis were seen in acute and chronic fascioliasis. Epidemiological investigations revealed that fascioliasis was higher in goats than sheep. Age, sex, BCS and season were found to have statistically significant associations with fascioliasis in goats. In case of sheep, age (OR = 5.8671; 95% CI: 2.9482 - 11.6757, P < 0.0001), sex (OR = 3.7317; 95% CI: 1.9052 - 7.3094, p < 0.0001), BCS (OR = 6.0346; 95% CI: 1.7986 - 20.2472, p <.0001), and season (OR = 8.2308; 95% CI: 3.9922 - 16.9693, p = <.0001) were also found to have statistically significant associations with fascioliasis. Results of the study can help for molecular epidemiology of fascioliasis in small ruminants to plan fluke control programs for safe food production.
Влияние противоопухолевых препаратов эруфозина и доксорубицина на развитие метастазов в яичках хомяков с миелоидной опухолью Graffi. Морфометрическое и гистологическое исследования
Authors: Илиева И. Н. , Саинова И. В. , Тошкова Р. А. , Георгиева А. К. , Нанев В. Н. , Цонева Р. Д.
Published: February 2024

Aim. The goal of the current study is directed to investigate the therapeutic effect of erufosine (ЕРС3) alone, as well as in combination with doxorubicin (DOX) on the development of metastases in the testes in an experimental model of transplantable Graffi myeloid tumor (GMT) in hamsters.

Materials & Methods. Experimental in vivo model of GMT in Golden Syrian hamsters was used. Animals were inoculated subcutaneously with live virus-transformed malignant cells. Testes from male tumor-bearing hamsters (TBHs), treated and non-treated with the antitumor agent erufosine alone or in combination with DOX, as well as untreated healthy controls, were subjected to morphometric and histological assays on the testicular architecture to evaluate potential antitumor/antimetastatic effects in in vivo conditions.

Results. The results showed no changes in blood vessels and morphology (impaired spermatogenesis and/or metastatic changes) of the testicular tissue in TBHs treated with antitumor agents (alone or in combination) compared to control healthy animals. In contrast, in the testes of TBHs without therapy, impaired spermatogenesis and foci of metastases, as well as significant changes in testicular blood vessels were found.

Conclusion. The data obtained demonstrated an antitumor/antimetastatic effect of EPC3 in the testes of hamsters in the experimental GMT model.
Ибрутиниб в лечении хронического лимфолейкоза у пациентов старше 60 лет из групп высокого и очень высокого риска
Authors: Куркина Надежда Викторовна , Репина Е. А. , Горшенина Е. И. , Куркина В. О. , Волкова П. В. , Репин А. А.
Published: February 2024

Aim. To assess the efficacy and tolerability of ibrutinib in chronic lymphocytic leukemia (CLL) therapy for high- and very-high-risk patients over 60 years of age.

Materials & Methods. The study enrolled 18 CLL patients aged 60 and older. The patients were stratified by age: group 1 included 10 patients aged 60–70 years (median age 64.5 years) and group 2 included 8 patients aged ≥ 71 years (median age 75.8 years); there was equal number of men and women. All patients were subjected to molecular genetic analysis to identify poor prognosis factors and determine the IGHV gene mutation status. The cytogenetic analysis revealed karyotypic abnormalities including 17p deletion in 3 female patients aged 60, 66, and 77 years, respectively. All the patients had CLL without mutation in IGHV genes. They received ibrutinib 420 mg/day per os as first- and second-line therapies.

Results. All patients showed aggravated comorbidity. The median follow-up was 28 months (range 18–42 months) in age group 1 and 46 months (range 12–78 months) in group 2. In group 1, a complete remission in 2 patients with del(17p) and a partial remission (PR) in 3 patients were achieved. PR with lymphocytosis was reported in the rest of 5 patients treated with ibrutinib for 12 months. In group 2, PR with the management of autoimmune complications in 5 out of 8 patients and PR with lymphocytosis in 3 patients were reported. The drug was well tolerated in both groups. No signs of severe hematological toxicity were observed in either of them.

Conclusion. The choice of ibrutinib for high- and very-high-risk CLL patients aged 60 and older appeared to be optimal. This is also proved by the ease of administration of oral capsules, high efficacy, absence of tumor lysis syndrome, good tolerability, and acceptable toxicity profile.
PREVALENCE OF VISUAL ACUITY DISORDERS AMONG INTERMEDIATESCHOOL STUDENTS IN RIYADH, SAUDI ARABIA 2022
Authors: Abdulaziz Aljetaily Mohanad
Published: February 2024

Our objectives in this study are to determine the prevalence of visual acuity disorders and to identify the important risk factors that associated with visual acuity disorders among Intermediate school students in Riyadh, 2022.Design.a cross sectional study was preformed the prevalence of visual acuity has been measured in Riyadh schools district. a sample size of 580 students throw a Multi-stage random sampling technic was conducted. The tools that has been used to collect data in this study are self administered questioner and the Snellen chart through placing it on 6 meter distance from the student, it contains C-letter-like shapes in different direction and sizes, which should be identified by the student. Study Sample: All Male intermediate school students in governmental schools in Riyadh city, 2022. which included a total of 580 students. Results: The prevalence of visual acuity impairment in our study was 14.3%, with a mean age of 14.14 Ã‚Â± 5.497 years old. 44.58 % of the students who are visually impaired didnt wear glasses. Mean hours spent on watching TV of visually impaired students is 4.02Ã‚Â± 2.437 and mean hours spent on reading 1.76 Ã‚Â± 1.061. Mean number of students who feel tired after time watching TV is 15.70%. There is increase in visual impairment among students as age increased. We observed that 60% of visually impaired students dont follow up with ophthalmologists. Conclusion: We found that there is a significant relationship between visual acuity impairment and inheritance. Also one of the risk factors among students who suffer from visual acuity impairment is that they dont regularly follow up with an ophthalmologist, and 44.58 % of the students who are visually impaired didnt wear glasses.
Color Profile of Ice Cream with Concentrates and Whey Protein Microparticles
Authors: Gurskiy Igor , Tvorogova A.
Published: February 2024

Ice cream is one of the most popular desserts all over the world because it possesses excellent sensory characteristics and is highly nutritional. Whey proteins can increase the biological value of ice cream. They are often used in non-fat dry milk powder to reduce its cost. However, whey proteins and casein differ in color. Therefore, replacing milk solids of non-fat proteins with whey proteins hay affect the color profile of the final product. The study registered the color changes in ice cream with different ratios of non-fat dry milk powder, microparticles, and whey protein concentrates. The spectrophotometric method made it possible to assess the key color characteristics, i.e., yellowness, whiteness, and overall color difference. Larger quantities of protein concentrates darkened the final product from 96 to 91.5. A mix of microparticles and whey protein concentrates had no effect on the color profile while each component applied on its own proved significant, as did some other variables. After replacing dry milk proteins, the whiteness index dropped to 85 whereas the yellowness index reached 18. The overall color difference showed that the consumer is likely to notice the replacement of dry milk powder with whey protein concentrates. However, the differences between samples with different ratios were either undetectable or insignificant. The obtained results can be used in qualitative tests to detect the presence of whey proteins in the ice cream protein composition.
Regional projects of public-private partnership in the field of waste management: The transition to a circular economy and sustainable development
Authors:   St. Petersburg State University, Maslova Svetlana V.
Published: February 2024

The concept of sustainable development is one of the dominant concepts in the twenty-first century, based on the need to strike a balance between addressing environmental and natural resource conservation, economic growth and meeting human needs and those of future generations. The concept of circular economy is considered as one of the means of progressive movement in the direction of sustainable development through the achievement of the UN Sustainable Development Goals. The transition to circular economy is one of the key strategic initiatives of the Russian Government to address the fundamental challenges of sustainable production and consumption, industrial development, construction, waste management, as well as environmental protection and climate change. Although in recent years the concept of circular economy has become increasingly important in the system of public administration, the search and implementation of practical mechanisms of transition to circular economy is relatively limited. The author of the study argues that the implementation of public-private partnership projects can bring significant benefits for the transition to circular economy, which, in turn, will contribute to the achievement of the sustainable development goals. The paper offers a framework for categorizing public-private partnership as a mechanism for transition to circular economy. The example of regional public-private partnership projects in the sphere of waste management, demonstrates how the framework can adapts the existing parameters of public-private partnership projects (their object and participants, prequalification requirements and tender criteria for private partner selection, public-private partnership agreement terms and financing instruments) to the conditions of their implementation in relation to circular economy and sustainable development goals. The author proposes a series of steps for scaling such public-private partnership projects.
The Art of Nikolai Estis in the Soviet Abstract Painting of 1950s–1980s
Authors:   HSE University, Brut Sorin
Published: February 2024

The work of the abstract artist Nikolai Estis is considered for the first time in the context of the Soviet version of abstract expressionism, which began to form during the Khrushchev thaw. The author analyzes the conditions, causes and sources that influenced the emergence of interest in abstractionism among a number of Soviet artists in the late 1950s, as well as the features of the forming of the abstract manner of Nikolai Estis. For the first time, a comparative analysis of the conceptual foundations and solutions of the works of Estis and other representatives of Soviet abstract expressionism such as Vladimir Nemukhin, Lidia Masterkova, Lev Kropivnitsky, Evgeny Mikhnov-Voitenko is carried out. The work of Estis is also compared with the works of Jackson Pollock that are consonant with him. The process of formation of Nikolai Estis as an abstract artist was significantly different from the folding of the abstract manner of his older contemporaries. Estis went to abstract painting gradually and wrote the first completely abstract works already in the 1970s. Accordingly, the meanings of abstract art associated with the period of the Khrushchev thaw affected his painting only partially. The works of Estis of the 1970s are the closest to the canvases of Vladimir Nemukhin and Lev Kropivnitsky of the 1950s and 1960s, but they also have significant differences. In the 1980s, the artist’s style changed and became closer to some of the early works of Yevgeny Mikhnov-Voitenko and the paintings of Jackson Pollock. At the same time, the works of the Moscow abstract artist remain original. The ideas of the work of Estis and the Soviet artists under consideration are in many ways close. They are associated with an attempt to escape from the everyday point of view and display the hidden device of reality. The study shows that the work of Nikolai Estis fits into the general line of development of the Soviet version of abstract expressionism. At the same time, in line with this direction, the painter managed to develop an individual manner.
The “Borderline” Monasteries of Tver and Their Role in Forming the Architectural Appearance of the City
Authors:   Moscow State University of Civil Engineering (National Research University), Salimov Alexey M.
Published: February 2024

Dating back to the deep Middle Ages, Tver, even at an early stage of its existence, included monasteries in the city structure. With a few exceptions, they usually appeared in the peripheral city zones. And still, thanks to the active development, these monasteries didn’t only quickly become important city-forming accents, but also contributed to the growth of the surrounding development. This stimulated an increase in the city area and inevitably deprived this monastery of a “borderline” status. However, new monastery ensembles appeared on the outskirts, and suburban ones, having been founded long before, got impulse for development. As a result, these “borderline” monasteries again became city-forming factors and contributed to the more intensive development of the part of the city they were connected with. The time of troubles at the beginning of the 17th century resulted in the loss of a number of monasteries. Their disappearance continued in the time of Peter the Great and in the following decades, when there was a strengthening of the secular principle in the life of the country. At the same time, there increased attention to the remaining monasteries, the vast majority of which can be attributed to the “borderline” ones, which stimulated the creation of large-scale architectural ensembles. In this respect, the “borderline” monasteries were a more significant factor in forming the surrounding development. And shortly before the revolutionary events, a similar trend was observed in the suburban monasteries closest to Tver. The active growth of residential development in close vicinity of these monasteries marked the “borderline” potential of the ones being suburban not so long before. However, this process was interrupted at the end of the 1910s, and only at the end of the 20th century one of the main functions of the monastery ensemble was restored.
Optimality and water conservation under non-system and system tank commands of Andhra Pradesh, India
Authors: Upadhyayula Madhurima , Karunakaran K. R. , Yeligar Sharath S.
Published: February 2024

Indian agriculture relies on irrigation. India's net irrigated area has tripled in 60 years, although tank-irrigated regions suffered a large decline. This study examines the potential for improving tank irrigation performance through linear programming by developing individual optimal plans for two different tank irrigation systems (non-system and system tank) in the Chittoor and Srikakulam districts of Andhra Pradesh, India. The optimal plans under non-system tanks allocated less land under paddy while improving groundnut areas to optimally reorganize resources among head, middle, and tail ends. Net returns were maximized to ₹ 2.63, ₹ 2.52, and ₹ 1.92 lakhs. The system tank optimal plans advised less water-intensive crops like pulses and sesame over sugarcane with maximized net returns of ₹ 5.35, ₹ 2.61, and ₹ 1.71 lakhs. Both physical (kg/m3) and economic water productivity (₹/m3) were highest among optimal crop mix under non-system and system tank command farms. Participatory water management, adoption of less water-intensive crops, and promotion of pressurized technologies were highly recommended in the study area and similar agro-climatic conditions
Seeded membrane distillation crystallization for hypersaline brine treatment
Authors: Flatscher Stefanie , Hell Florian , Hlawitschka Mark W. , Lahnsteiner Josef
Published: February 2024

Brine evaporation and crystallization are energy- and equipment-intensive technologies commonly used in industries. Alternatively, membrane distillation (MD) has shown ability for concentrating different saline solutions. However, there is a limited understanding of the impact of these solutions on the scaling and wetting behavior. To address this knowledge gap and reduce costs and energy consumption, we investigated a novel method called ‘seeded near-zero liquid discharge membrane crystallization’ (NZLDMC). This approach combines MD and crystallization in a single apparatus, reducing capital and operating costs while improving sustainability. Our study focused on applying seeding processes at NZLDMC for concentrating synthetic mono- and multi-salt solutions with a salinity of 300 g/L and a real salt solution. We investigated the effects of salt crystals and seeds on membrane performance under different operating conditions. Our findings indicate that seeding crystal technology leads to high yield and long-term stability, thereby offering the potential in industries and municipal water treatment to fractionate salt in multi-salt solutions and obtain purified water simultaneously.
The influence of public perception on acceptance of potable water reclamation schemes. The case of Diepsloot township, Johannesburg
Authors: Tshililo Fhulufhelo Phillis , Mutanga Shingirirai Savious , Gumbo Trynos , Sikhwivhilu Keneiloe , Chikozho Claudious
Published: February 2024

While a considerable amount of research in several parts of the world has already demonstrated reclaimed water safety and reliability for various uses, its acceptance and use by communities and households in South Africa remains very low. In this article, we use quantitative and qualitative data from a community-level cross-sectional perception survey that was carried out from 2018 to 2019 to assess water users' willingness to accept reclaimed water as an alternative source of water for domestic purposes in Diepsloot township as well as the main factors influencing respondents' perceptions. Results of this study show that there is high acceptance of reclaimed water for domestic uses. Respondents with higher levels of education were more likely to accept reclaimed water than those with lower levels of education. The assumption that the water they were using was already mixed with wastewater also increased water user's acceptance levels. The results of the study suggest that governments, municipalities, and other key actors in the water and sanitation sector should first work towards building community trust and confidence when establishing water reclamation projects for domestic use, particularly through strategic communication and awareness-raising initiatives before they can expect widespread community acceptance.
A tolerant hydrologic technique for real-time selection of optimum QPFs from NWPMs for flood warning applications
Authors: Salah Mahmoud , El-Mostafa Ashraf , Gad Mohamed A.
Published: February 2024

The most important information required to successfully issue a flood warning is the quantitative precipitation forecasts (QPFs). This is important to run subsequent rainfall–runoff simulations. A rainfall–runoff simulation derives its accuracy mainly from the accuracy of the input QPFs. The dynamically based global numerical weather prediction models (NWPMs) are strong candidate sources of QPFs. A main problem is the real-time selection of which NWPM should be used to provide the QPFs for flood warning simulations. This paper develops an automated technique to solve this problem. The technique performs real-time comparisons with measured rainfall fields using a novel ‘tolerant’ hydrologic approach. The ‘tolerant’ approach performs the comparison on the basin scale and allows for timing shifts in the forecasts. This is because QPFs can be good but only a few hours early or late. Two events are used for illustration, and the proposed real-time application in flood warning is presented. The developed technique, employing the tolerant approach, could eliminate the effects of the timing shifts and, accordingly, succeeded to select the QPFs to be used. A Python package was developed for automation. The developed technique is expected to also be useful for offline assessments of historical performances of NWPMs.
Integrated assessment of available water volume for sustainable sponge city construction – A case study in Xi'an, China
Authors: Luo Li , Su Dong , Wang Tong , Guo Wenshan
Published: February 2024

To address the lack of theoretical guidance for sponge city construction (SCC) in China, this study introduces a method to evaluate the available water volume (AWV) in urban watersheds. This evaluation is based on the water balance relationship, water volume, and ecological water demand (EWD). The Xi'an urban area was selected as a case study due to its water shortage and flooding issues. Results show monthly surface and subsurface AWV ranging between 53.06 and 53.98 million m3 and between 8,701.89 and 8,898.14 million m3, respectively. By maximizing the potential for surface AWV, an annual water supply of 527.75 million m3 could be provided, surpassing the annual artificial water consumption of 394.20 million m3, effectively addressing water scarcity. During the rainy season, implementing measures such as employing permeable paving materials, establishing wetlands and rainwater gardens, and constructing lakes and reservoirs can mitigate flooding caused by rainfall exceeding 32.8 mm. While the subsurface space in Xi'an holds significant potential for subsurface AWV utilization, revitalizing the ecological environment of subsurface water is crucial. Overall, the AWV theoretical framework offers a comprehensive solution to water shortage and flooding issues in the Xi'an urban area, serving as a vital theory for SCC.
SEQUÊNCIAS DE ENSINO COM ENFOQUE SOCIOCIENTÍFICO NA INTERFACE COM AS CORRENTES DE EDUCAÇÃO AMBIENTAL
Authors: Fonseca Aleson da Silva , Costa Ivaneide Alves Soares da
Published: February 2024

Objetivou-se analisar sob a perspectiva vygotskyana as macrotendências político-pedagógicas-ideológicas da educação ambiental, identificadas em sequências de ensino constituídas em um curso de formação docente fundamentadas na abordagem de Questões Sociocientíficas (QSC). Ao final da formação solicitou-se a elaboração de sequências de ensino, obtendo-se 21 propostas didáticas que foram analisadas para enquadramento das correntes político-pedagógicas de Educação Ambiental. Verificou-se a predominância do viés pragmática (14 sequências), críticas (4 sequências), conservacionistas (2 sequências), uma não foi possível encontrar elementos suficientes para o enquadramento. Esse resultado decorre do processo de construção da identidade e desenvolvimento sócio-histórico, ao qual os professores foram submetidos ao longo do seu desenvolvimento cognitivo. Por isso recomenda-se, que as formações pedagógicas, que pretendem subsidiar a preparação para o trabalho docente com o uso de QSC, carecem de uma base teórica de vertente crítica, como possibilidade de enfrentamento das ideologias reducionistas, tecnicistas e positivistas desse universo educativo.
Peculiarities of legal regulation of property relations of spouses when carrying out business activities and exercising corporate rights
Authors:   Larisa V. Kudryavtseva Kuban State Agrarian University named after I.T. Trubilin, Kudryavtseva Larisa V. , Gulikov Andrey A. ,   Andrey A. Gulikov Kuban State Agrarian University named after I.T. Trubilin
Published: February 2024

В статье рассмотрены спорные ситуации супругов при разделе доли в уставном капитале предприятия при разводе супругов. В статье раскрывается вопрос о правовом режиме доходов, полученных супругами от предпринимательской деятельности. Выявлено отсутствие единообразного подхода к оспариванию сделок, связанных с изменением размера уставного капитала предприятия. Предлагается будущим супругам до вступления в брак заключать брачный договор либо мирное соглашение, чтобы избежать негативных последствий для предприятия.
The concept and legal nature of the bank deposit agreement
Authors:   Larisa I. Popova Kuban State Agrarian University, Popova Larisa I. , Stepanov Dmitry V. ,   Dmitry V. Stepanov Kuban State Agrarian University
Published: February 2024

В статье авторами анализируется правовая природа договора банковского вклада. Исследуются существующие авторские и законодательные подходы к пониманию правовой природы договора банковского вклада. В заключение авторы приходят к выводу о самостоятельности правовой природы договора банковского вклада. Говорится, что договор необходимо рассматривать в качестве самостоятельного, публичного гражданско-правового договора, а также договора присоединения, имеющего собственную правовую природу, несмотря на присущие данному договору элементы заемного обязательства.
Analysis of professional training of mediators in modern Germany
Authors:   Alexey V. Kudryavtsev Vladimir branch of RANEPA, Kudryavtsev Alexey V. , Eyvazov Ruslan A. ,   Ruslan A. Eyvazov  Central Territorial Administration of the Federal Agency for Railway Transport of the Ministry of Transport of the Russian Federation, Eyvazov Alishir Sh. ,   Alishir Sh. Eyvazov Vladimir branch of RANEPA, Kosaeva Svetlana R. ,   Svetlana R.Kosaeva Vladimir branch of RANEPA
Published: February 2024

Объектом исследования является профессиональная подготовка медиаторов в современной Германии. Предметом исследования служат актуальные проблемы подготовки и профессионального становления медиаторов. С использованием общенаучных методов рассмотрены требования немецкого законодательства к профессиональной подготовке медиаторов. В ходе исследования отмечены основные принципы профессиональной подготовки, предлагаемые немецким законодательством о медиации. Критический анализ исследования позволил выявить основные профессиональные и личностные характеристики современного немецкого медиатора. Новизна исследования заключается в проведение авторами сравнительных сопоставлений требований к профессиональной подготовке медиаторов на современном этапе развития рынка медиации в Германии. Авторами указана необходимость разработки профессиональной подготовки медиаторов в Российской Федерации и их обязательное законодательное закрепление. Сделаны выводы о том, что наилучших результатов достигают специалисты, прошедшие полный курс обучения и, как правило, с наличием нескольких базовых образований.
Legal basis for the introduction of electronic document management at the university
Authors:   Ruslan Ab. Abdusalamov Dagestan State University, Abdusalamov Ruslan Ab.
Published: February 2024

В статье рассмотрены правовые основы электронного документооборота в образовательных учреждениях России. Определены преимущества внедрения электронного документооборота и возможные препятствия на пути его реализации. Особое внимание уделяется практическим и правовым пробелам, связанным с фактическим использованием и нормативной регламентацией особенностей и порядка реализации электронного документооборота в вузах. В частности, делается акцент на технических трудностях повсеместного перехода от бумажной документации к электронной во всех вузах; проблеме квалификации преподавательского состава; пробелах в правовом регулировании электронного документооборота. С учетом выявленных практических трудностей и правовых проблем в рамках указанного вопроса предлагаются пути разрешения практических трудностей и направления совершенствования действующего законодательства. Представляется, что сформулированные выводы и предложения могут быть использованы в научных, правоприменительных и законотворческих целях.
Features of the problems of protecting the rights and freedoms of man and citizen in the Russian Federation at the present stage
Authors:   Naida А. Gazimagomedova Dagestan State University, Gazimagomedova Naida А.
Published: February 2024

В статье рассматриваются шесть особенностей, характерных для защиты прав человека в современной России с учетом сложившейся международной обстановки и вызовов, обусловленных внесенными поправками в Конституцию РФ в 2020 г. в правозащитной сфере. Последовательное рассмотрение и учет этих особенностей будут способствовать формированию эффективной национальной правозащитной системы, особенно касательно регионов – субъектов РФ Северо-Кавказского федерального округа, которые наиболее отстают в социально-экономическом развитии.
On the issue of the constitutional model of local self-government in the Russian Federation
Authors:   Dzhuma V. Kamilova Dagestan State University, Kamilova Dzhuma V.
Published: February 2024

В настоящее время вновь меняется статус местного самоуправления ввиду вступивших в силу изменений. Вопрос новой модели местного самоуправления, его прав и обязанностей вновь остро встает как перед практиками, так и перед наукой. Актуальным остается вопрос о месте местного самоуправления в структуре управления государством. Автором статьи сделан анализ конституционной модели местного самоуправления, сложившейся в Российской Федерации, раскрыты ее отличительные особенности. Делается вывод о том, что эффективности реформирования рассматриваемого института будет способствовать более четкое разграничение полномочий между органами государственной власти и местного самоуправления.
Problems of providing public services to the population on the basis of multifunctional centers in the Republic of Dagestan
Authors:   Aminat Z. Arslanbekova Dagestan State University, Arslanbekova Aminat Z. , Khaibulaeva Raisat G. ,   Raisat G. Khaibulaeva The MFC branch in Kazbekovsky district
Published: February 2024

В статье проведён анализ становления, развития и современного состояния деятельности многофункциональных центров на территории Республики Дагестан, результатов реализации проекта «Создания сети многофункциональных центров в РД». Выделены основные направления развития многофункциональных центров в Республике Дагестан. Сделан вывод, что многофункциональный центр – это новый формат взаимодействия государства и гражданина, ориентированный на комплексное удовлетворение потребностей гражданина в государственных и муниципальных услугах. Одной из главных целей, достигнутых по итогам реализации проекта «Создания сети многофункциональных центров в РД», является создание положительного имиджа государственной власти, выразившегося в многочисленных положительных отзывах заявителей о деятельности многофункциональных центров.
The quality and safety of food products as a factor affecting the health of the population: issues of legal support
Authors:   Elena V. Vorontsova Southwest State University, Vorontsova Elena V.
Published: February 2024

В статье анализируется проблема качества и безопасности продуктов питания как фактора общественного здоровья. Отмечается, что состояние здоровья современных россиян ставит под сомнение возможность устойчивого развития нашего общества в ближайшей и отдаленной перспективе. При этом многие проблемы общественного здоровья обусловлены качественными характеристиками потребляемой пищи. В этой связи автор анализирует потенциальные риски для здоровья граждан, возникающие на российском пищевом рынке вследствие применения в агроиндустрии технологий генной инженерии, фармакологии и др. Исследуется организационно-правовой механизм обеспечения качества и безопасности пищевой продукции, указывается на его несовершенство, связанное с дисбалансом правового регулирования вопросов качества и безопасности. Обосновывая необходимость придания требованиям качества обязательного характера, автор в то же время указывает на возможные негативные последствия императивного правового регулирования сферы производства пищевой продукции. Выход из создавшейся проблемной ситуации автор видит в выборе оптимальной юридической формы сочетания публично-правовых и частноправовых интересов в данной сфере и предлагает собственные подходы к формированию системы управления качеством пищевой продукции.
On the issue of the subjects of professional and public accreditation of educational programs in the sphere of legal education
Authors:   Viktoriya T. Azizova Dagestan State University, Azizova Viktoriya T.
Published: February 2024

В статье освещаются проблемные аспекты определения субъектов проведения профессионально-общественной аккредитации образовательных программ в сфере юридического образования касательно всех уровней – от среднего специального юридического образования до подготовки кадров высшей квалификации в аспирантуре и адъюнктуре. В ходе анализа Перечня организаций, проводящих профессионально-общественную аккредитацию образовательных программ высшего образования и (или) соответствующих дополнительных профессиональных программ, применительно к сфере юридического образования были выявлены проблемы определения аккредитующих организаций в отношении всех уровней юридического образования. В частности, к экспертной деятельности в отношении образовательных программ юридического образования допускаются организации, имеющие весьма опосредованное отношение к сфере юриспруденции. В связи с выявленными проблемами формирования субъектного состава аккредитующих организаций обозначены меры по преодолению указанных проблем. Вносится предложение о необходимости включения в список документов, представляемых для формирования Перечня организаций, проводящих профессионально-общественную аккредитацию образовательных программ высшего образования и (или) соответствующих дополнительных профессиональных программ, реестра экспертов, обладающих необходимым набором профессиональных качеств, позволяющих в полной мере и квалифицированно проводить профессионально-общественную аккредитацию образовательных программ в рамках юридического образования.
Analysis of Self-Care Activities in Type 2 Diabetes in Brazil: Protocol for a Scoping Review
Authors: Toledo Marileila Marques , da Silva Edson , Esteves Elizabethe Adriana
Published: February 2024

Background

Diabetes mellitus is a chronic disease that is growing worldwide. It is estimated that 15.7 million people aged between 20 and 79 years live with diabetes in Brazil, and the majority of cases are type 2 diabetes (T2D). To successfully manage diabetes, the patient needs to develop self-care activities. However, there is limited understanding of what self-care activities are performed by people with T2D in Brazil.

Objective

This study aims to identify and map studies that evaluate self-care activities in T2D in Brazil.

Methods

This is a scoping review protocol structured according to the methodological guidelines of the Joanna Briggs Institute. Six databases and gray literature were used. The process of searching, identifying, and evaluating the papers was carried out by 2 independent reviewers, guided by the assumptions established by the Joanna Briggs Institute. We sought to answer the following guiding question: How are self-care activities for people with T2D evaluated in Brazil? We included papers and publications in any language, from public and private domains, and with different methodological approaches.

Results

Initial database searches produced a total of 681 results. These papers will be critically analyzed, and relevant information will be extracted. Quantitative and qualitative results of the papers reviewed will be presented to respond to the study’s objective. We intend to publish the scoping review in the first half of 2024.

Conclusions

The protocol for this scoping review will evaluate the main self-care activities carried out by adults and older people with T2D in Brazil. The results may help identify knowledge gaps and contribute to future research and diabetes education interventions.

International Registered Report Identifier (IRRID)

DERR1-10.2196/49105
The Impact of Broadband Infrastructure Construction on Medical Resource Mismatch: Quasi-Natural Experiment From the Broadband China Policy
Authors: Chai Yulin , Yuan Xiaoping , Guo Lin , Chen Zhongming
Published: February 2024

Background

Whether the construction of broadband infrastructure can alleviate the problem of mismatched medical resources is crucial to the national information strategy, residents’ well-being, and social equity. However, the academic community lacks a comprehensive theoretical analysis and rigorous empirical research on this issue.

Objective

This study aims to construct a preliminary theoretical framework to scientifically assess the effects of broadband infrastructure development on the mitigation of health care resource mismatch from both theoretical and empirical perspectives, to explore the potential mechanisms of influence, and ultimately to develop several practical policy recommendations.

Methods

We first used a theoretical analysis to propose testable theoretical hypotheses and establish a preliminary theoretical framework. Then, based on balanced panel data from 300 cities from 2010 to 2021, a 2-way fixed effects difference-in-differences model was used for empirical testing. Mechanism tests, robustness analyses, and heterogeneity analyses were further conducted.

Results

The research findings demonstrate that the Broadband China Policy significantly reduces the degree of mismatch in medical resources by primarily using innovation effects and integration effects, resulting in a reduction of 13.2%. In addition, the heterogeneity analysis reveals that the central and eastern regions, cities with large populations, and areas with a high proportion of young people benefit more significantly.

Conclusions

This study fully confirms, both theoretically and empirically, that broadband infrastructure construction can effectively reduce the mismatch of medical resources not only by expanding the existing literature on the impact of broadband on public services but also by providing valuable opportunities for policy makers to optimize the allocation of medical resources.
Overdose Detection Among High-Risk Opioid Users Via a Wearable Chest Sensor in a Supervised Injecting Facility: Protocol for an Observational Study (Preprint)
Authors: Tas Basak , Lawn Will , Jauncey Marianne , Bartlett Mark , Dietze Paul , O'Keefe Daniel , Clark Nico , Henderson Bruce , Cowan Catriona , Meredith Osian , Strang John
Published: February 2024

BACKGROUND

Opioid overdose is a global health crisis, affecting over 27 million individuals worldwide, with more than 100,000 drug overdose deaths in the United States in 2022-2023. This protocol outlines the development of the PneumoWave chest biosensor, a wearable device being designed to detect respiratory depression in real time through chest motion measurement, intending to enhance early intervention and thereby reduce fatalities.

OBJECTIVE

The study aims to (1) differentiate opioid-induced respiratory depression (OIRD) from nonfatal opioid use patterns to develop and refine an overdose detection algorithm and (2) examine participants’ acceptability of the chest biosensor.

METHODS

The study adopts an observational design over a 6-month period. The biosensor, a small device, will be worn by consenting participants during injecting events to capture chest motion data. Safe injecting facilities (SIF) in Melbourne, Victoria (site 1), and Sydney, New South Wales (site 2), which are legally sanctioned spaces where individuals can use preobtained illicit drugs under medical supervision. Each site is anticipated to recruit up to 100 participants who inject opioids and attend the SIF. Participants will wear the biosensor during supervised injecting events at both sites. The biosensor will attempt to capture data on an anticipated 40 adverse drug events. The biosensor’s ability to detect OIRD will be compared to the staff-identified events that use standard protocols for managing overdoses. Measurements will include (1) chest wall movement measured by the biosensor, securely streamed to a cloud, and analyzed to refine an overdose detection algorithm and (2) acute events or potential overdose identified by site staff. Acceptability will be measured by a feedback questionnaire as many times as the participant is willing to throughout the study.

RESULTS

As of April 2024, a total of 47 participants have been enrolled and data from 1145 injecting events have already been collected, including 10 overdose events. This consists of 17 females and 30 males with an average age of 45 years. Data analysis is ongoing.

CONCLUSIONS

This protocol establishes a foundation for advancing wearable technology in opioid overdose prevention within SIFs. The study will provide chest wall movement data and associated overdose data that will be used to train an algorithm that allows the biosensor to detect an overdose. The study will contribute crucial insights into OIRD, emphasizing the biosensor’s potential step forward in real-time intervention strategies.

CLINICALTRIAL

INTERNATIONAL REGISTERED REPORT

DERR1-10.2196/57367
A CHRONOLOGICAL ANALYSIS OF INFLATION DYNAMICS IN KENYA
Authors: Kimolo Deogratius Wenceslaus , Odhiambo Nicholaus , Nyasha Sheilla
Published: February 2024

This paper undertakes an exploratory examination of inflation dynamics in Kenya between 1970 and 2021, employing a descriptive research design and secondary data from various sources, coupled with qualitative analysis of the literature. The paper comprehensively analyzes the impact of diverse policy changes, including monetary and fiscal policies. Overall, this paper provides a beneficial resource for anyone interested in comprehending the intricacies of inflation dynamics in Kenya and the relevant measures employed to manage rising prices. The government implemented various measures to fight inflation over the years, including tight monetary policy and fiscal policy measures. The Central Bank of Kenya implemented various monetary policies to control inflation, such as increasing interest rates and tightening credit. Factors such as rising food and fuel prices, droughts, and political instability have driven inflation in Kenya over the years. Despite Kenya's implementation of several reforms aiming to promote stable inflation over time, challenges regarding inflation persist. To achieve long-term economic growth and stability, it may be wise for the government to consider implementing policies that promote fiscal discipline, strengthen institutional frameworks, and encourage private sector development. By doing so, the government can ensure sustainable economic growth and stability.
INVESTIGATING FINANCIAL FRAUDS IN THE MODERN LANDSCAPE: A FORENSIC ACCOUNTING PERSPECTIVE IN THE COVID-19 ERA
Authors: Pavlović Miloš , Đukić Tadija , Gligorić Čedomir
Published: February 2024

This paper explores the evolving landscape of forensic accounting, particularly in the context of changing financial frauds and the challenges posed by the COVID-19 pandemic. The progression of financial fraud over time, driven by technological advancements and shifting business environments, highlights the necessity for adaptive and innovative approaches to fraud detection and prevention. Advanced methodologies, including data analytics, digital forensics, and artificial intelligence, have empowered forensic accountants to confront increasingly sophisticated fraud schemes. The examination of frauds arising from the pandemic underscores the resilience of fraudsters in exploiting vulnerabilities during crises. This paper underscores the importance of forensic accounting in upholding financial integrity, ethical standards, and business resilience. It calls for continuous research, innovation, and vigilance in the field of forensic accounting to counter emerging fraud schemes and evolving business landscapes.
CONFLICTS IN THE ORGANIZATION: HOW CAN MEDIATION AFFECT THE DEVELOPMENT OF THE ORGANIZATION?
Authors: Kvitka Yuliia , Andreieva Kateryna , Kvitka Anton , Prus Yuliia
Published: February 2024

Modern organizations in conditions of globalization and high uncertainty have not only a complex development trajectory, but also face a high number of organizational conflicts (both internal and external). For the stable functioning of organizations and the creation of comfortable working conditions for their employees, it is important to implement effective methods of resolving conflict situations, such as mediation, into organizational practice. The aim of the paper is the systematization of the modern approaches to organizational conflicts and assessment of the mediation influence on organizational development on the example of the social and healthcare spheres. Also, research is devoted to identification of the main causes of conflicts in institutions of the social and healthcare, participants in conflicts, methods of their resolution. Empirical research was conducted with the involvement of 88 representatives of social and healthcare institutions from three regions of Ukraine (Dnipro, Zaporizhzhia, and Kharkiv). Within the framework of the research, the frequency and types of conflicts that arise in organizations of the social sphere and healthcare were studied. The causes of conflict situations are considered, the influence of conflicts on the development of modern organizations was determined. The key areas of work on conflict resolution and prevention were identified according to employees. The degree of awareness of employees regarding the mediation procedure was determined and the readiness for its implementation in organizations of the social sphere and healthcare was assessed. Directions for further research into the impact of conflicts and mediation on the development of modern organizations are proposed.