bluuebunny/crossref_metadata_2025 huggingface dataset:
Therapeutic Thrombocytapheresis as an Important Tool in the Management of Symptomatic Hyperthrombocytosis
Authors: Das Sudipta Sekhar , Biswas Rathindra Nath , Sen Subrata , Chakrapani Anupam
Published: April 2022

Background & Objectives:

Hyperthrombocytosis may cause acquired thrombosis-related symptoms and fatal vascular complications. Currently, therapeutic platelet reduction (TPR) with medical therapy remains the mainstay of hyperthrombocytosis management. We encounter patients with high platelet counts with requests for TPR. Here, we share our experience of TPR procedures in patients with symptomatic hyperthrombocytosis due to various underlying etiologies.

Methods:

The study from January 2013 to October 2020 included 36 patients of hyperthrombocytosis who underwent 82 TPR procedures by apheresis technology. Patient details were obtained from the treatment file and all procedures were performed following recommended instructions and protocol. Statistical analysis was done using the SPSS statistical package.

Results:

The median age of patients was 53 years with mean hemoglobin, platelet count, plateletcrit, and platelet distribution width of 9.9 g/dL, 1711.3 × 106/mL, 0.57%, and 43.4%, respectively. A total of 26 patients had primary thrombocytosis. The mean TPR procedure time, whole blood volume processed, and anticoagulant used were 162 min, 5070 mL, and 430.3 mL, respectively. The mean reduction of platelets in patients who underwent two and three procedures was 72.4% and 82.7%, respectively (P = 0.003).

Conclusion:

We conclude that TPR is a useful method in reducing platelet count rapidly in hyperthrombocytosis. It relieves patients of acute symptoms and prevents thrombotic events. The decision to perform TPR should be individualized and based on the clinical scenario, degree of thrombocytosis, and risk factors associated with TPR procedures.
Cw Alloimmunization in Multitransfused Thalassemic Patients of North India
Authors: Pahuja Sangeeta , Sehgal Shivali , Sharma Geetika , Chandra Jagdish , Parakh Nupur , Singh Manisha , Yadav Ramvilash
Published: April 2022

Background and Objectives:

The C Willis or Cw antigen is a low-incidence antigen of Rh system. The antibody against the Cw antigen (anti-Cw) is an IgG antibody which may occur naturally or may be immune in nature. The identification of Cw antibody is important since it has the potential to cause hemolytic disease of the newborn as well as hemolytic transfusion reaction. This study was conducted with the aim of determining the prevalence of Cw antibody in multitransfused thalassemic patients enrolled in a Regional Blood Transfusion Center (RBTC) of North India.

Methods:

A retrospective descriptive observational study was conducted at the Department of Immunohematology and Blood Transfusion, LHMC and Associated Hospitals. All transfusion-dependent thalassemic (TDT) patients and non-TDT (NTDT) patients enrolled in the RBTC of the hospital till December 2018 were included in the study. Antibody screening was performed in all recipients before each transfusion. The prevalence of anti-Cw was estimated.

Results:

A total of 567 thalassemic patients (including TDT and NTDT) were registered in RBTC, LHMC till December 2018. On pretransfusion antibody screening and identification, 3 out of 567 thalassemic patients were found to have alloimmunization against Cw antigen. The prevalence of anti-Cw in multitransfused thalassemics was 0.53%.

Conclusion:

The prevalence of anti-Cw is variable in different populations and it is not a very commonly reported antibody in patients with thalassemia. One should be aware of the approach to transfusion in thalassemic patients who develop Cw alloimmunization.
Promoter methylation of matrix metallopeptidase 9 in peripheral blood mononuclear cells: A novel biomarker in a promising source for noninvasive colorectal cancer diagnosis
Authors: Shaygannejad Alireza , Sohrabi Behnoush , Rad Shima Rahimi , Yousefisadr Farzaneh , Darvish Hossein , Soosanabadi Mohsen
Published: April 2022

Objectives:

Colorectal cancer (CRC) has been described as a “silent disease,” which can be readily treated in most patients when discovered in its early stages. Considering the limitations of the current conventional tests for the diagnosis of CRC, researchers strive to find noninvasive and more valid biomarkers for the early detection of CRC. It has been shown that tumor-specific methylation patterns can also be identified in peripheral blood mononuclear cells (PBMCs) and are reliable sources of methylation analysis for CRC screening.

Materials and Methods:

We carried out a quantitative methylation analysis on matrix metallopeptidase 9 (MMP9) promoter using methylation quantification endonuclease-resistant DNA (MethyQESD) method. A total of 70 patients with CRC and 70 normal controls were enrolled in this study for methylation analysis in the PBMCs.

Results:

Our findings discovered a considerable hypermethylation of MMP9 promoter in CRC patients compared with healthy controls (mean: 47.30% and 20.31%, respectively; P > 0.001). The sensitivity and specificity of the MMP9 gene for the diagnosis of CRC were 88% and 78%, respectively. In addition, on the basis of area under the curve values, the diagnostic power of the MMP9 gene was 0.976 (P < 0.001). Moreover, our analysis established that MMP9 methylation was significantly different between the different stages of CRC (P: 0.034).

Conclusions:

Our results showed that MMP9 promoter methylation in PBMCs can be used as an outstanding biomarker for CRC diagnosis. Besides, we confirmed that PBMCs are reliable sources of methylation analysis for CRC screening and MethyQESD is an accurate and fast method for quantitative methylation analyses.
Anesthesia for Per-oral endoscopic myotomy (POEM) – not so poetic!
Authors: Sarkar Soumya , Khanna Puneet , Gunjan Deepak
Published: April 2022

Peroral endoscopic myotomy (POEM) is a promising natural orifice transluminal endoscopic procedure for the treatment of esophageal motility disorders, with similar effectiveness as of Heller myotomy. It is performed under general anesthesia in endoscopy suite. Creation of submucosal tunnel in the esophageal wall is a key component. The continuous insufflation of CO2 inadvertently tracks into surrounding tissues and leads to capno mediastinum, capno thorax, capno peritoneum, and subcutaneous emphysema. Thus, the challenges, for an anesthesiologist are not only providing remote location anesthesia, increased risk of aspiration during induction, but also early detection of these complications and specific emergency management. Though a therapeutic innovation, POEM remains an interdisciplinary challenge with no specific anesthesia care algorithms and evidence-based recommendations. The purpose of this review is to outline the anesthesia and periprocedural practices based on existing evidence.
Patient satisfaction with anaesthesia services in a tertiary care cancer centre. (SAY study)
Authors: Ambulkar Reshma , Patel Alim , Patil Sanika , Savarkar Sukhada
Published: April 2022

Background and Aims:

Patient satisfaction is an important measure of quality of health care. Its assessment leads to a balanced evaluation of the structure, process and outcome of service at an institution. The aim of our study was to assess patient satisfaction with perioperative anaesthesia services provided in our institution and identify factors leading to dissatisfaction which could be preventable or addressed to improve patient care and experience.

Material and Methods:

A convenient sample size of 200 patients was accrued after written informed consent. A questionnaire to suit local needs of institute was developed, validated and a language appropriate questionnaire was administered by a trained research nurse 24–48 hours post anaesthesia to accrued patients. Data was summarised in percentages and satisfaction scores were compared across demographic variables using Chi square test.

Results:

A total of 96% (192/200) patients were satisfied with the overall interaction with the anaesthetists in the perioperative period; with 99% (198/200) patients being satisfied with acute pain services provided, postoperatively. As regards to recovery room, 96.5% (193/200) patients were satisfied with the services provided. Satisfaction scores of the pre-anaesthetic clinic (PAC), pain team and anaesthesia services compared across demographic variables – age, gender and education qualifications were found to be statistically non-significant.

Conclusion:

High rate of patients were satisfied with perioperative anaesthesia care services at our institute. Good and effective preoperative communication with the patient, effective management of postoperative pain and complications significantly contributed towards overall high patient satisfaction.
Outcomes of Posterior Approach Surgery in Various Types and Grades of Upper Eyelid Blepharoptosis in Indian Eyes
Authors: Pandey Nidhi , Singh Swati
Published: April 2022

PURPOSE:

To present the outcomes of levator plication (levatorpexy) surgery by posterior approach for correction of ptosis of different aetiologies in Indian eyes.

METHODS:

Retrospective review of clinical notes and clinical photos of consecutive ptosis patients who underwent levatorpexy from January 2017 to September 2018. Surgery was considered successful if the following four criteria were simultaneously met: a postoperative MRD1 of ≥2 mm and ≤4.5 mm, inter eyelid height asymmetry of ≤1 mm, no overcorrection compared to the opposite eye, and a satisfactory eyelid contour determined by patient.

RESULTS:

Thirty six eyelids of 36 patients (mean age, 23.6 years; 25 females) underwent unilateral levatorpexy with the left eyelid affected in 66.6 %. Twenty one congenital (58.3%) (C), 12 (33.3%) aponeurotic (A) and 3 (8.3%) complex ptosis (CX) had a mean levator function of 9.8 mm (range, 6 to 15). Mean pre and post operative margin reflex distance (MRD 1) was 0.611mm (range, -1 to 3 mm) and 3 .00 mm (range, 2 to 4 mm) respectively. At the final follow up of 12 months, four patients remained under corrected (11.1%). At the final follow up of twelve months, the success rate was 78 percent.

CONCLUSION:

Posterior approach for ptosis repair offers a scar less, minimally invasive, easy to revise, and successful lid height correction in congenital and acquired ptosis.
Evaluation of the Systemic Inflammation in Patients with Pterygium
Authors: Belviranli Selman , Oltulu Refik , Gundogan Ali O. , Mirza Enver , Okka Mehmet
Published: April 2022

PURPOSE:

The purpose of this study is to evaluate systemic inflammation in patients with pterygium using the monocyte-to-high-density lipoprotein cholesterol ratio (MHR) and hematologic indexes of inflammation.

METHODS:

Thirty-one patients with primary pterygium and 31 age-and sex-matched healthy participants were enrolled in this retrospective study. The MHR, neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio, platelet-to-lymphocyte ratio, eosinophil-to-lymphocyte ratio, monocyte-to-eosinophil ratio, mean platelet volume-to-platelet count ratio, platelet distribution width, and red cell distribution width were compared between the two groups.

RESULTS:

There was not a statistically significant difference in terms of the MHR between the pterygium group and the control group (P = 0.693). The NLR was higher in the pterygium group than in the control group (P = 0.028). In the other hematologic indexes, there were no statistically significant differences between the two groups (P > 0.05 for all).

CONCLUSION:

The MHR is not associated with the presence of pterygium. An increased NLR in patients with pterygium may be an indicator of systemic inflammation.
Information Communication Technology in Medical Practice
Authors: Emejulu Jude-kennedy C. , Nkwerem Sunday Patrick , Adimekwe Mary C.
Published: April 2022

Background:

Information communication technology (ICT) is increasingly being used in medicine for teaching and clinical practice. It reduces physical contact and travel time and minimizes the risk of nosocomial infections, including COVID-19. It provides good channels of interaction among medical practitioners as well as between physicians and patients. In Sub-Sahara Africa, the windows of opportunity provided by these platforms, especially WhatsApp, Instagram, electronic mail, are still underused. Reasons include hostile legal atmosphere.

Aim:

This study aims to review the level of use and awareness of legality of WhatsApp, E-mail, and Instagram in a tertiary hospital in the South Eastern Nigeria.

Materials and Methods:

This was a cross-sectional study in which a pro forma was generated and sent to the contacts of doctors working in the above institution. The forms willingly filled and turned in were analyzed.

Results:

About 108 respondents willingly filled and turned in their forms. M: F ratio was 2:1, the modal age group was 20–30 years. About 36.6%, 22.6%, 12.9%, and 8.6% of respondents were in surgery, pediatrics, internal medicine, and family medicine, respectively. About 98.1% of respondents believed in the use of ICT; however, only 10% of respondents used it frequently in the management of patients. Among those respondents that used it, it was mostly for inpatient care. About 43.3% of respondents are convinced that there is no legal backing for ICT in Nigeria. About 86.6% of respondents are waiting to take advantage of ICT when proper law is put in place.

Conclusion:

There is a need for better advocacy and amendment of relevant law to enhance use of ICT.
Effects of Birth Preparedness and Complication Readiness on Pregnancy Outcome in Nigeria
Authors: Umeh Uchenna Anthony , Umeh Chioma Roseline , Ugwu Emmanuel Onyebuchi , Imediegwu Obioha Odoeme , Oguejiofor Nnaemeka Christopher , Grema Bukar Alhaji , Nwankwo Ogochukwu Theophilus , Eleje George Uchenna , Agu Polycarp Uchenna
Published: April 2022

Background:

Birth preparedness and complication readiness (BPCR), a component of focused antenatal care, has a great potential to reducing maternal and newborn deaths in low-income countries. However, the success of this strategy is not well known in most of sub-Saharan Africa, and the effectiveness of the strategy has not been widely studied.

Aims:

This study aimed at evaluating the effects of BPCR on pregnancy outcome.

Materials and Methods:

This was an observational cohort study of eligible consecutive pregnant women presenting in labour at a tertiary hospital in Abakaliki, Nigeria. Maternal and neonatal outcomes of labour were compared between women who had a birth plan (n = 115) and a control group without a birth plan (n = 115).

Results:

The mean age of the parturients was 27.87 ± 5.20 years. Women who had a birth plan were less likely to have postpartum anaemia (P < 0.001), receive blood transfusion (P < 0.001), and have prolonged hospital stay (P = 0.03). Their neonates were at less risk of low birth weight (P = 0.02) and admission into newborn special care unit (P = 0.003). There was no association between BPCR and incidence of Caesarean section (P = 0.65) and maternal satisfaction (P = 0.20).

Conclusion:

The practice of BPCR in Abakaliki, Nigeria, is associated with some favourable maternal and neonatal outcomes. The study findings indicate the need for more advocacies for adequate implementation of BPCR during pregnancy in Nigeria.
Correlation of Axial Length, Lens Thickness, and Anterior Chamber Depth in Patients Undergoing Cataract Surgery
Authors: Ezeh Ernest Ikechukwu , Chinawa Elijah Ndubuisi , Ezeh Roseline Nkeiruka
Published: April 2022

Background:

Axial length, lens thickness and anterior chamber diameter are valuable parameters used in determining the refractive status of the eye.

Aim:

To determine the correlation between axial length (AL), crystalline lens thickness (LT), and preoperative anterior chamber depth (ACD) among patients undergoing cataract surgery.

Patients, Materials and Methods:

It was a cross-sectional study done over a one-year period. One hundred and fifty-one adults with cataract in both eyes were consecutively recruited. Using an optical biometer Ultrasound A/B Scan (Chong Qing Kang Hua S&T Co., Ltd, CAS-2000BER [Model A], China), ocular biometric data including AL, ACD, and LT were assessed for both eyes before cataract operation for either eye. Pearson's correlation and regression analyses were applied to determine relationships between the biometric variables. Statistically, significance was taken as P < 0.05.

Results:

One hundred and fifty-one (302 eyes) adult participants were studied, consisting of 77 (51.0%) males and 74 (49.0%) females. The age range was 12–88 years, with a mean age of 57.73 ± 14.87 years (95% confidence interval, 54.70–59.90). Correlation analysis revealed that AL and ACD were positively correlated (r = 0.164, P = 0.002). AL and LT demonstrated a statistically insignificant and very weak positive correlation (r = 0.071, P = 0.217). ACD was negatively correlated with LT (r = −0.375, P = 0.000). On multiple regression, AL (z-score = 0.191) and LT (z-score = −0.387) were significant predictor estimates of the regression model for ACD (P = 0.000); a hypothetical equation for ACD was generated: ACDpredicted = 2.978 + (−0.522 × LT in mm) + (0.106 × AL in mm).

Conclusion:

LT is an important biometric parameter that should be considered, along with other biometric parameters, in determining effective lens position in patients undergoing cataract surgery. The narrowing of ACD with age is largely due to increasing LT. Using an optical biometer, ACD is predominantly influenced by LT than the AL.
The South-Western Boundary of Central Paratethys
Authors:   Faculty of Mining Geology and Petroleum Engineering, University of Zagreb, Croatia, Pavelić Davor
Published: April 2022

Small Neogene basins within the Dinarides were never invaded by marine transgressions during their evolution. The fresh-water sedimentation, endemic fauna and their position between the Adriatic region and the Pannonian Basin System explain why these basins have not been considered as parts of the Mediterranean or Central Paratethys realm. The correlation of sediments and fauna of these fresh-water basins with the Pannonian Basin System and Adriatic region suggests that Dinaridic fresh-water basins may be considered as a part of the Central Paratethys. This consideration locates the southwestern boundary of Central Paratethys within the High Karst Belt.
Исследование малых возмущений стационарного состояния в модели верхнегибридных плазменных колебаний
Authors: Rozanova Olga Sergeevna
Published: April 2022

Показано, что постоянное внешнее магнитное поле, вообще говоря, не способно предотвратить опрокидывание (потерю гладкости) релятивистских плазменных колебаний, даже если они являются сколь угодно малыми возмущениями нулевого состояния покоя. Этот результат резко отличается от нерелятивистского случая, для которого можно подавить опрокидывание колебаний при любых начальных отклонениях путем увеличения интенсивности магнитного поля. Тем не менее даже в релятивистском случае существуют подклассы решений, соответствующие глобально гладким по времени решениям.
Задача о деформации полосы в трех моделях гидродинамики
Authors: Pukhnachev Vladislav Vasilievich
Published: April 2022

Изучается задача о деформации прямолинейной полосы, ограниченной твердой непроницаемой стенкой и параллельной ей свободной границей. Рассматриваются три модели несжимаемой жидкости: идеальная жидкость, классическая вязкая жидкость и разбавленный раствор полимера. Выявлено влияние вязкого и релаксационного факторов на качественную картину движения.
О доказательстве существования вынужденных колебаний с помощью добавления диссипативных сил
на примере сферического маятника
Authors: Polekhin Ivan Yur'evich
Published: April 2022

Рассматривается обобщение задачи Уитни о периодическом движении перевернутого сферического маятника при наличии горизонтальной периодической силы на случай, когда маятник также находится в поле сил, зависящих от скорости. Рассматривается метод введения в систему дополнительных диссипативных сил, позволяющий доказывать существование периодических решений в исходной задаче.
Квазигармоническая продольная волна, распространяющаяся в стержне Миндлина-Германа, погруженном в нелинейно-упругую среду
Authors: Erofeev Vladimir Ivanovich , Leontieva A V
Published: April 2022

Рассматривается модуляционная неустойчивость квазигармонической продольной волны, распространяющейся в однородном стержне, погруженном в нелинейно-упругую среду. Динамическое поведение стержня определяется теорией Миндлина-Германа, уточняющей техническую теорию стержней. Точность модели достигается за счет описания движения частиц стержня в поперечном направлении при отказе от гипотезы, что поперечные деформации при осевом растяжении или сжатии пропорциональны продольной деформации. Система уравнений, описывающая продольные колебания стержня, сводится к одному нелинейному уравнению четвертого порядка относительно продольного смещения частиц стержня. Методом многих масштабов получено нелинейное уравнение Шредингера - одно из основных уравнений нелинейной волновой динамики. С помощью критерия Лайтхилла определены области модуляционной неустойчивости. Показано, как границы этих областей смещаются при изменении параметров, характеризующих упругие свойства материала стержня и нелинейность среды. Проанализировано влияние параметров системы на волновые пакеты и основные параметры солитонов огибающих (амплитуда, скорость, ширина).
Уединенные внутренние волны с захваченным ядром в многослойной мелкой воде
Authors: Lyapidevskii Valerii Yur'evich , Chesnokov Aleksandr Aleksandrovich
Published: April 2022

Рассматривается нелинейная система уравнений, описывающая в приближении Буссинеска распространение придонных и приповерхностных внутренних волн большой амплитуды в многослойной стратифицированной мелкой воде под крышкой. Получены гладкие стационарные солитоноподобные решения уравнений движения в виде симметричных и несимметричных волн второй моды, примыкающих к заданному постоянному потоку. Показано, что построение гладкого решения, в котором один из слоев имеет конечную длину (захваченное ядро), может привести к образованию сингулярности. В классе функций с кусочно-гладкими первыми производными предложен метод построения решений с захваченным ядром. Для многослойных уравнений мелкой воды приведены примеры стационарных решений, описывающих солитоноподобные структуры и течения с захваченным ядром.
Efeito de borda sobre atributos funcionais das árvores num remanescente de restinga, Rio de Janeiro
Authors: Zuñe Felipe , Melo Eliza Christina do Nascimento , Lopes Rosana Conrado
Published: April 2022

Objetivou-se avaliar o efeito de borda com base nas diferenças dos atributos funcionais das árvores (densidade da madeira, diâmetro e altura) na restinga de Grumari, RJ, região de Floresta Atlântica. Em campo, delimitaram-se duas bordas: Banco Halles e Lagoa Feia. Em cada borda foram selecionadas árvores com diâmetro ≥ 10 cm. Registrou-se o diâmetro e a altura de cada árvore, sendo também coletadas amostras de madeira. A densidade da madeira foi obtida pelo método de imersão. Os testes t de Student e Wilcoxon foram utilizados na análise dos atributos funcionais para verificação de diferenças entre bordas. A correlação de Pearson foi aplicada para constatar relações entre os atributos. Adicionalmente, estimou-se a biomassa das árvores e comparou-se a média entre bordas. Foi observado que apenas a altura apresentou diferenças significativas entre bordas (t 2,55; p 0,02). Os atributos funcionais não apresentaram relações significativas entre si e a borda Banco Halles apresentou maior estoque médio de biomassa (126,48 ± 71,14 kg) do que Lagoa Feia (71,5 ± 40,67 kg). Este estudo sugere que o efeito de borda poderia estar influenciando a variação dos atributos funcionais em um mesmo remanescente com diferentes históricos de distúrbio e ocupação.
WORKSHOP PEMBUATAN MEDIA PEMBELAJARAN QUIS INTERAKTIF MENGGUNAKAN MICROSOFT POWERPOINT BAGI GURU SMPN 1 WAIGETE
Authors: Rahmawati Tanti Diyah , Safrudin Nurfitriah , Chotimah Nur , Fitriah Fitriah , Salwiana Salwiana
Published: April 2022

With the increasing development of technology, teachers are required to be able to master IT in learning. A variety of active and interactive learning media can motivate students in learning. This causes the need for interactive, fun, and easily accessible media. This service aims to provide knowledge and practice on making interactive learning media in the form of quizzes using PowerPoint. The results of this service got an excellent response from the teachers at SMPN 1 Waigete. With the resulting Quiz media in the form of PPT, the teachers felt that the media was beneficial and provided much knowledge that had not been obtained so far. It can be seen from the results of the questionnaire that mastery can make media quizzes using PPT 60%, while 40% still need guidance and assistance. Thus, the teachers feel that this service activity is significant to increasing their IT knowledge, and they hope that they will not stop making quizzes but can continue with other IT training because the teachers' mastery at SMPN 1 Waigete is still minimal
PELATIHAN PENGENALAN KETERAMPILAN PRA MATEMATIKA YANG KREATIF DI TK ALQUR’AN TAQARRUB
Authors: Sihotang Siti Fatimah , Zuhri Zuhri
Published: April 2022

Pre-mathematics is an important activity to train children to construct understanding with symbolic language called simple abstraction then teach children to understand the concept of numbers and number operations. One of the pre-mathematical activities or skills for early childhood is sorting and classifying (grouping activities). Sorting and grouping skills are very important because this activity can hone children's ability to observe similarities and differences. Unfortunately for the current condition of children, where the covid-19 pandemic is still ongoing which of course requires children to do a lot of activities at home, making early childhood children play less, especially understanding the importance of playing while learning. In fact, the introduction of playing and learning activities through pre-mathematical activities is very useful when children enter the elementary school (SD) level. Thus, seeing the importance of understanding pre-mathematical skills for teachers in Alqur'an Taqarrub Kindergarten to be taught to students, this service activity aims to provide information as well as improve pre-mathematical abilities and skills for teachers in Alqur'an Taqarrub Kindergarten. through pattern recognition, activity and classification of creative activities for early childhood, so that they can be directly applied and applied to students. The implementation method used is the Transfer of Knowledge with activity stages; 1) preparation; 2) Implementation; and (3) Evaluation. In general, PKM can run according to the schedule of activities and there is an increase in knowledge and skills about pre-mathematical skills, through creative activities. The teachers are also proven to have been able to understand various pre-mathematical skills and are able to make examples of creative and fun questions to teach students.
Critical Dialogues
Authors: Clarke John
Published: April 2022

In this engaging and original book, John Clarke is in conversation with twelve leading individual scholars about the dynamics of critical thinking in the social sciences, and he reflects on the necessity of thinking collaboratively and dialogically.
Comparing the Performance of Prediction Model of Ridge and Elastic Net in Correlated Dataset
Authors: Bastiaan Richy Marcelino , Salaki Deiby Tineke , Hatidja Djoni
Published: April 2022

Multicollinearity refers to a condition where high correlation between independent variables in linear regression model occurs.Â  In this case, using ordinary least squares (OLS) leads to unstable model. Some penalized regression approaches such as ridge and elastic-net regression can be applied to overcome the problem. Penalized regression estimates model by adding a constrain on the size of parameter regression. In this study, simulation dataset is generated, comprised of 100 observation and 95 independent variables with high correlation. This empirical study shows that elastic-net method outperforms the ridge regression and OLS.Â  In correlated dataset, the OLS is failed to produce a prediction model based on mean squared error (MSE)
Distribution of Spread and Characteristics of Confirmed Covid-19 based on Spatial Autocorrelation in Manado
Authors: Pontoh Sophia Olga , Weku Winsy , Hatidja Djoni
Published: April 2022

Covid-19 is a collection of viruses that attack the respiratory system. This virus spread quickly and spread to other regions in China and most countries in the world, including Indonesia. North Sulawesi Province, especially Manado City is one of the cities in Indonesia that has been affected by Covid-19. The highest confirmed Covid-19 cases in Manado City are in the Malalayang, Mapanget, and Wanea villages which are geographically not adjacent/neighboring. This study aims to analyze the spatial distribution of Covid-19 cases and their characteristics. This study uses significant data on Covid-19 cases in every village in Manado City, where there are 86 villages (Malayang Satu Barat Village and Malalayang Satu Timur Village combined), and the focus of this research is on the confirmed variables, with the latest data update is October 21, 2021. The effect of covid-19 between observation locations is accomplished using Moran's I, and the weighting matrix used is the Euclidean distance matrix. The Moran's Index provides an overview of the spatial relevance of the Covid-19 case data in every village in Manado City and specifically the spatial attachment of every village will be explained by the Local Moran's I value (LISA). The results of this study found that there is a spatial autocorrelation found using the Euclidean distance matrix. A spatial correlogram of 30 meters is used as the maximum geographical distance limit for being infected with Covid-19. The Moran's Index value of the Covid-19 case in Manado City is 0.348, meaning that there is a positive autocorrelation between the villages. There are thirteen villages that affect the spread of Covid-19 in Manado City, namely Malalayang Satu Timur dan Barat, Malalayang Satu, Winangun Satu, Kleak, Karombasan Utara, Ranotana Weru, Bumi Nyiur, Pakowa, Tinkulu, Taas, Paal Empat, Tikala Baru, and Paniki Dua.
Design Web-Based Information System of Tri Dharma Higher Education for Lecturer
Authors: Anastasia Lenshy Aprisilia , Pinontoan Benny , Latumakulita Luther Alexander
Published: April 2022

Tri dharma of higher education consisting of education & teaching, research, and community service which must upheld by every lecturer at universities in Indonesia. Lecturer who has implemented the tri dharma of higher education need these tri dharma files for promotion and lecturer performance report to get allowance. It is important to have an online system to store those files. In this research we develop a web-based information system for processing lecturer tri dharma activities data using Rapid Application Development (RAD) Method which started from requirement planning, system design, and implementation.
Analisis Meningkatkan Simpan Pinjam Koperasi dan UKM pada Masa Covid-19 di Provinsi Sumatera Utara
Authors: Mandasari Sheila Putri , Arif Muhammad
Published: April 2022

Cooperatives are a necessary and important economic institution. Cooperatives are a form of joint effort based on the principle of family to improve welfare. And cooperatives have a goal to increase economic activity. Cooperatives and MSMEs have contributed significantly to regional and national income, especially in the North Sumatra Province. MSMEs play a role in absorbing labor in the distribution of development results. During the COVID-19 pandemic, the majority of the economic sector, especially MSMEs, could not develop and many ended up in bankruptcy and a slowdown in the economic sector in Indonesia with its various derivatives. The Micro, Small and Medium Enterprises (MSMEs) sector which is the most important part of the economic sector that is feeling the impact of the COVID-19 pandemic. During the Covid-19 period, MSMEs experienced various problems such as decreased sales, capital, distribution was hampered, raw material difficulties, decreased production and the occurrence of many layoffs for workers and hunting which later became a threat to the national economy. With the purpose of this research, the analysis is to increase Savings and Loans for Cooperatives and Small and Medium Enterprises (UKM) during the Covid-19 period in North Sumatra Province, this research method is by taking secondary data and interviews, solving problems using qualitative methods from existing descriptions. in the mass media and then concluded by researchers.

Keywords : Savings and Loans, UKM, Covid 19
The Use of Clitics In Novel “Murder on The Orient Express” By Agatha Christee
Authors: Setiani Rulik , Dewi Sri Kuning
Published: April 2022

Clitics are words or parts of words that are structurally depend on neighboring words (it is the host) and cannot stand alone. The objectives of the research are 1) to investigate the types of clitics in the Novel “Murder on the Orient Express” by Agatha Crhistee. 2) to investigate the dominant types of clitics in the novel “Murder on the Orient Express” by Agatha Crhistee. This research used qualitative descriptive method and the instrument used was the researchers. The data of this research is taken from the novel “Murder on the Orient Express” by Agatha Christee. The data analysis technique used is Miles and Huberman technique, the steps are: data reduction, data display, and drawing conclusion and verification. From the research results obtained that the researchers found 699 clitics. There are 22 proclitics and 677 enclitics. Proclitic only has two kinds (o') and (d'). While enclitic has eight kinds, namely ('m), ('re), ('ll), ('ve), ('d), ('s), (n't), and genetive ('s) and the percentage shows that enclitic is 96.85% greater than the proclitic is 3.15%. So it can be concluded that enclitic is the most dominant used in novel Murder on the Orient Express by Agatha Christee.
Literature Review Evaluasi Implementasi Sistem Informasi Manajemen Rumah Sakit (SIMRS) Dengan Metode Hot-Fit
Authors: Khasanah Lina , Fajar Imani Farhan
Published: April 2022

Perkembangan teknologi sistem informasi di Rumah Sakit membawa pengaruh yang besar dalam kesuksesan organisasi. Rumah Sakit sebagai organisasi yang kompleks memerlukan dukungan sistem teknologi informasi yang lengkap, akurat serta sesuai dengan kebutuhan dan tujuan rumah sakit tersebut untuk mendukung kegiatan operasionalnya agar berjalan efektif dan efisien. Evaluasi suatu sistem informasi merupakan suatu usaha nyata untuk mengetahui kondisi sebenarnya suatu penyelenggaraan sistem informasi. Dengan evaluasi tersebut, capaian kegiatan penyelenggaraan suatu sistem informasi dapat diketahui dan tindakan lebih lanjut dapat direncanakan untuk memperbaiki kinerja penerapannya. Tujuan dari penelitian ini adalah untuk mengetahui gambaran evaluasi sistem informasi manajemen rumah sakit (SIMRS) dengan menggunakan metode Hot-Fit. Metode yang digunakan dalam penelitian ini adalah literature review. Objek dalam penelitian ini merupakan jurnal 5 tahun terakhir. Pengumpulan data yang digunakan adalah data sekunder. Analisis data dilakukan secara deskriptif kualitatif  dengan teknik literature review yaitu mencari kesamaan, ketidaksamaan, pandangan, bandingkan dan ringkasan terhadap beberapa penelitian. Hasil dari 5 jurnal literature bahwa pelaksanaan SIMRS belum berjalan lancar hal ini disebabkan masih terdapat kendala dari aspek manusia banyaknya petugas yang belum memahami dan mengerti dalam menggunakan SIMRS dikarenakan tidak adanya pelatihan, dari aspek organisasi kurangnya dukungan, pengawasan, serta evaluasi dari pihak manajemen, dan dari aspek teknologi kualitas jaringan yang kurang baik serta kualitas informasi dan layanan yang belum maksimal. Kesimpulan Implementasi SIMRS belum berjalan secara optimal yang disebabkan masih ditemukannya beberapa kendala di ketiga faktor yaitu Manusia, Organisasi dan Teknologi. Diharapkan pihak terkait agar lebih memperhatikan dan mempersiapkan segala sesuatu terkait SIMRS dengan baik.
STUDENT SATISFACTION OF ITSK Acupuncture Study Program RS dr. SOEPRAOEN KESDAM V/BRW MALANG TOWARDS ONLINE LEARNING METHODS
Authors: Wulandari Mayang , Mahadini Chantika
Published: April 2022

Pendahuluan. Metode pembelajaran daring belum pernah dibayangkan dan direncanakan sebelumnya, namun karena situasi darurat demi keselamatan maka apapun dilakukan agar pendidikan tetap berlangsung dengan segala kekurangan dan kelebihannya. Pembenahan dan inovasi mandiri terus dilakukan, kesiapan perangkat, kualitas jaringan, kuota internet, dan kesiapan sumber daya manusia menjadi kebutuhan utama saat ini. Metode. Metode yang digunakan adalah pendekatan analisis deskriptif kualitatif untuk mengolah data primer yang diperoleh. Populasi pada penelitian ini adalah mahasiswa Program Studi Akupunktur ITSK RS dr Soepraoen Kesdam V/ BRW Malang dengan total sampling 231 orang. Data penelitian diperoleh dengan menggunakan kuesioner / google form yang diisi secara daring oleh mahasiswa. Analisis respon mahasiswa menggunakan Skala Guttman. Hasil. Dari total 231 mahasiswa menjawab 9 pertanyaan tentang E learning dengan hasil 227 mengenal, 230 bisa mengoperasikan, 220 menjawab kuliah tetap menarik, 223 menjawab dengan E learning kuliah menjadi fleksibel, 202 menjawab hasil belajar bisa optimal, 222 orang menjawab dengan E learning masih bisa berkomunikasi dengan dosen, 216 merasa puas, 222 menjawab dengan E learning kuliah menjadi hemat biaya, dan 200 merasa lebih baik menggunakan E learning untuk perkuliahan selanjutnya. Kesimpulan. Mahasiswa Prodi Akupunktur ITSK RS dr Soepraoen Kesdam V/ BRW Malang puas terhadap Metode Pembelajaran Daring.      

Kata kunci: Daring, Fleksibel, Kepuasan.
TERAPI NERS GENERALIS: SESI 1 PADA KLIEN DENGAN KEKAMBUHAN RISIKO PERILAKU KEKERASAN DENGAN PENDEKATAN TEORI PEPLAU: LAPORAN KASUS
Authors: Wandira Shella Ayu , Alfianto Ahmad Guntur , Ulfa Miftakhul
Published: April 2022

Pendahuluan : Perilaku kekerasan pada rang dengan gangguan Jiwa disebakan kekambuhan. Upaya yang dapat dilakukan dengan terapi ners generalis dan pendekatan teori Peplau. Tujuan studi ini adalah mengidentifikasi ke efektifan terpai ners generalis Sesi 1 pada klien dengan kekambuhan risiko perilaku kekerasan dengan pendekatan teori Peplau  Metode : studi ini menggunakan pendekatan case report dengan juhmal responden sebanyak 5 orang yang mengalamai kekambuhan risiko perilaku kekerasan. Kriteri inkulis responden mengalami kekambuhan akibat obat, sering mengalami kekambuhan dan risiko perilaku kekersan. Studi ini dilaksanakan di Desa Bantur pada bulan Novemebr 2021 dengan instrument yang digunakan adalah asuhan keperawatan jiwa pendekatan Stuart. Hasil : responden mampu melakukan tindakan keperawatan pada terapai ners generalis sesi 1 yaiatu mengenal, penyebab, gejala perilaku kekerasan serta melakukan teknik nafas dalam dan memukul bantal dengan pendekatan teori Peplau dengan 4 fase yaitu orientasi, indentifiksi, eksploitasi dan resolusi. Namun pada fase eksploitasi respon subjetif responden belum dikerjakan dengan semuprna. Kesimpulan : terapi ners generalis sesi 1 pada responden dengan kekambuhan risiko perilaku kekerasan dengan pendekatan teori Peplau teratasi dengan baik namun pada fase eksploitasi terdapat respon subjektif yang tidak sempurna pada salah satu reseponden.
PENERAPAN MODEL INDEX CARD MATCH UNTUK MENINGKATKAN HASIL BELAJAR SISWA PELAJARAN IPS KELAS IV MIN 8 ACEH BARAT
Authors: Andhika M. Rezki , Setiawan Andra
Published: April 2022

Lack of active student interaction in learning such as joint discussions between students and teachers, as well as the lack of application of learning models that can support student activity. The learning outcomes of fourth grade students of MIN 8 West Aceh can be seen from the low level of student learning outcomes. The research target is how teacher activities, student activities and student learning outcomes through the application of the Index Card Match model on Theme 5 My Heroes in Class IV MIN 8 West Aceh. This study aims to describe teacher activities, student activities, and student learning outcomes during learning. The research instruments used in this study were teacher activity observation sheets, student activity observation sheets, and test question sheets. In this study, researchers used Classroom Action Research (CAR) which was carried out in the classroom by using an action to improve the quality of the learning process in order to obtain better learning outcomes than before. The data analysis technique used is using the percentage formula. Based on observations of teacher activity in the first cycle, the percentage was 73% (good), and in the second cycle it increased to 90% (very good). Meanwhile, student activity in the first cycle obtained a percentage of 72% (good) and the second cycle increased to 84% (very good). While the student learning outcomes obtained in the first cycle only 12 students who completed with a value of 60% and who did not complete 11 students with a value of 40%. While in the second cycle there was an increase, namely 20 students achieved completeness with a score of 86% and 3 students did not complete with a score of 14%. Based on the results of data analysis, it can be obtained that the use of the Index Card Match learning model can improve student learning outcomes.
PERCOBAAN PEMBUNUHAN SEBAGAI MAWANI‘ AL-IRTH DALAM KHI PASAL 173 DILIHAT MENURUT PERSPEKTIF MAQASID Al-SYARI‘AH
Authors: Mawaddah Lailatul
Published: April 2022

Trial of Assassination is an action carried out with the intention of killing people, but the person who wants to be killed does not die. In KHI Article 173 stated that the trial of assassination were prevented from inheriting, but in fiqh did not mention this, because that was the result of  ijtihad by Indonesian Islamic law experts. Based on this, this research attempted to explain the provisions of the KHI regarding the trial of assassination as mawani' al-irth, and the provisions of KHI regarding the trial of assasination as mawani‘ al-irth seen in the motivations behind it. Both of these will be studied using the perspective of maqasid al-syari'ah. The type of research used in this thesis is library research (qualitative research). Sources of data from this study come from the book al-Muwafaqat, Tasyri 'al-Jinaai al-Islami, Al-Fatawa al-Fiqhiyyah al-Kubra, Al-Tahzib fi Fiqh Imam Al-Syafi'i and the book Compilation of Islamic Law by Cik Hasan Bisri, as well as books and journals relating to maqasid al-syari'ah and mawani' al-irth. Data collection method is carried out in documentation and data analysis method in the form of qualitative descriptive. The results of the study indicate that the provisions of the KHI Article 173 concerning trial of assassination that’s hindered from inheriting is not suitable to be applied. Because the trial of assassination does not cause a person to die. Then in KHI also do not recognize the term forgiveness, even though the opportunity to be forgiven by the own heir is very large. Furthermore, in KHI, it does not consider the background of doing this action, even though between one person and another person has different intentions and objectives. Although the trial of assassination is a case that violates the existence of maqasid al-syari‘ah from the needs of the dharuriyyah, which is guarding the soul (hifz al-nafs), the benefit here is to apply a law according to the conditions that it wants. Because the basic purpose of Islamic law (maqasid al-syari‘ah) is to gain benefit and prevent damage (mafsadah).
TINJAUAN QANUN ACEH NOMOR 5 TAHUN 2016 TENTANG PENCABUTAN QANUN NOMOR 9 TAHUN 2014 TENTANG PEMBENTUKAN BANK ACEH SYARI’AH
Authors: Mukhlisuddin Teuku
Published: April 2022

The existence of Qanun Number 5 of 2016 concerning the Revocation of Qanun Number 9 of 2014 concerning the Establishment of the Aceh Sharia Bank has caused disputes among Acehnese elite figures. For the government, the revocation of Qanun Number 9 of 2014 is a step to speed up conversion. Meanwhile, according to M. Jafar, the implementation of the conversion of Bank Aceh from the conventional system to sharia does not require Qanun, except for the formation of a new bank or spin off (separation). In fact, the Financial Services Authority (OJK) instructed the Aceh government to revoke Qanun Number 9 of 2014 to speed up conversion permits from the Financial Services Authority. So that the authors are interested in exploring deeper information about the reasons for the Aceh government to revoke Qanun Number 9 of 2014 concerning the establishment of Bank Aceh Syariah in the form of a spin off. This type of research is a library research using a normative juridical approach, namely Qanun Number 5 of 2016 concerning the revocation of Qanun Number 9 of 2014 concerning the Establishment of the Aceh Sharia Bank.  From this research, it can be seen that the Aceh Qanun which was issued in 2014 and then revoked by the Aceh government in 2016 is not a requirement to obtain a license to convert Conventional Aceh Bank into sharia.
HUBUNGAN ANTARA AGAMA DAN NEGARA DALAM PERSPEKTIF PEMIKIRAN ISLAM
Authors: Zulfahmi Zulfahmi
Published: April 2022

This paper examines religious and state relations of Islamic thought perspective. This study aims to describe how the relationship between religion and state in the view of Islam. The method used in obtaining data is descriptive method through literature study. The results of the study show that among Muslim figures or thinkers such as Nurcholish Madjid and Abdur Rahman Wahid agree that there is a constructive relationship between state and religion which by revivalists separates it. Some of the indicators are: (1) Islam gives the principles of the formation of a state with the concept of khalīfah, dawlah, or hukūmah, (2) Islam emphasizes the democratic values of truth and justice, and (3) Islam upholds Human Rights by stating that the basic rights that human beings bring ever since they are born are the right of religious freedom. Therefore, Islam essentially emphasizes the importance of human rights to be upheld in a state, because human rights are rights that should not be disturbed and deprived from the person who has the right.
La elección del nombre de bautismo en el siglo XVI: el caso de Jacinto
Authors: Rodríguez Toro José Javier
Published: April 2022

El trabajo se concentra en el estudio del nombre Jacinto (y de su femenino Jacinta) en el siglo XVI. Para ello se han analizado todos los libros de bautismo conservados en los archivos parroquiales de Sevilla, con especial atención a los de la principal parroquia de la ciudad, la del Sagrario de la Santa Catedral. Del análisis llevado a cabo se desprende que este antropónimo, sin apenas testimonios a lo largo del siglo, se hizo muy frecuente en el último lustro como nombre simple y como elemento integrante de nombres dobles (por ejemplo, Juan Jacinto). El motivo de esta extraordinaria difusión, comprobable en todos los sectores sociales, parece ser la canonización de Jacinto de Cracovia, declarada en abril de 1594. El papel de la Iglesia sevillana debió de ser fundamental en este fenómeno.
Resources and sources in anthroponomastic studies: a review of contemporary references-TRAD
Authors: Fernández Juncal María Carmen
Published: April 2022

This paper investigates the various sources that can serve as a starting point for the study of anthroponomastic processes. We examine two types of resources for this kind of research. On the one hand, we can access more or less established repertoires, as is the case of the database provided by public institutions in different countries (censuses, registers, statistical agencies, among others), whose purpose as a public service is open and multifunctional. On the other hand, this list can be complemented by other compilations of very different origin and purpose that can be used in a subsidiary manner. These corpora are mostly compiled by the onomastics researcher himself, who uses tools such as interviews, surveys or other mechanisms from which onomastic catalogues can be established, as well as gathering other relevant information in the processes that take place to determine the impact of certain parameters in the attribution processes, specifically in that which affects personal names.