bluuebunny/crossref_metadata_2025 huggingface dataset:
Differentiated tillage system in the forest-steppe zone of the Middle Volga region
Authors: Kuzina E. V.
Published: February 2023

Evaluation of agroeconomic efficiency of different tillage systems for mustard, cultivated in a grain fallow rotation with the following alternation of crops: complete fallow - winter wheat – spring wheat - mustard is presented. The experiments were made in a field experiment in the forest-steppe zone of the Middle Volga region in 2019-2021. The soil of the experimental plot is slightly leached medium-powered heavy loamy chernozem. Tillage horizon is characterized by the following agrochemical parameters: humus content of 5.8 to 6.1%, the provision of mobile phosphorus is high (226 mg/kg), the potassium is medium (92 mg/kg), the reaction of the soil solution is close to neutral (pH 6.6). The object of the study is the mustard variety Rhapsody, the subject of the study is soil tillage systems. The expediency of replacing the annual classic plowing with a differentiated treatment in the rotation, based on the alternation of deep plowing and surface disc cultivation is established. It positively affects the process of formation of agrophysical, biological and agrochemical properties of soil, contributes to the conservation of productive moisture reserves, and helps to reduce weed infestation of crops. This treatment leads to a significant increase in the yield by 0.11 t/ha, allows for the highest yields of 199% (on average for the backgrounds) and the highest energy factor of 1.33, which is 71 and 22% higher than on the option with the annual mouldboard plowing. It was noted that the used mineral fertilizers at a dose of N30P30K30 did not produce the desired effect. Lack of yield growth led to the formation of negative economic indicators when making mineral fertilizers in all the variants studied, with the exception of differentiated treatment in the rotation. In this variant, the maximum increase in the yield by 0.25 t/ha and the cost of gross output by 7500 rubles/ha, which is 1521 rubles/ha higher than the increased production costs is noted. In the option with annual mouldboard plowing fertilization was accompanied by a decrease in the net income and profitability levels by 965 rubles/ha and 75% relative to the non-fertilized background, indicating that the unprofitable use of fertilizers.
The effect of feeding level on the genetic variability of female minks
Authors: Loenko N. N. , Kulikov V. N. , Lyudnov I. P. , Kosovsky G. Yu.
Published: February 2023

The results of the assessment of individual genetic variability in young female short-haired mink at different biological periods are presented. The experiments were conducted under the conditions of the existing technology of housing and feeding in 2019, 2020. For the experiment, two groups of 40 rearing females (at the age of 2 months) of the short-haired mink of the standard black breed (Neovison vison) were formed. The control group of females at the age of 2-4 months was fed according to the recommended energy standards. The experimental group of females was limited in the level of feeding (in terms of energy) by 10.0%. The frequency of erythrocytes containing microkernels in the peripheral blood of females was found to depend on the level of feeding during different periods of ontogenesis and the reproductive cycle phases. This method can be used to predict the reproductive success of female minks. The frequency of erythrocytes with microkernels in the rearing female minks of the control group at the age of 4 months during the formation of their reproductive functions was 2 times higher than in the experimental group (2.97 ± 0.42 vs. 6.01 ± 2.75‰). At the age of puberty (10 months) the frequency of erythrocytes with microkernels in rearing females is statistically significantly higher - 14,36 ± 1,87-14,89 ± 3,67‰ (p < 0,05; p < 0,01), than at the age of 4 months. The following productivity indices were obtained in the studied females of the control and experimental groups: the fertility of females - 5,63 ± 0,64 and 5,67 ± 0,77 pups, the yield of pups per a main female - 4,4 ± 0,77 and 4,67 ± 0,85 pups respectively. There were no unbred females and those which mated with males but did not have a litter in the experimental group, and the yield of pups per a female was 0,27 more. The microkernel test can be used to assess the stability of the genetic apparatus during different phases of the reproductive cycle of female minks and predict the reproductive success of females.
Comparative virulence properties of epizootic strains of Escherichia coli bacteria
Authors: Galiakbarova A. A. , Pimenov N. V.
Published: February 2023

The results of the study to determine the virulence of production strains and epizootic isolates of Escherichia coli isolated in the Moscow and Tula regions in livestock farms and in the private sector from 2016 to 2022 are presented. In the experiment, the virulence of Escherichia coli was studied by determining the LD50 of Escherichia coli isolates for biological test systems. The most virulent strain from the museum collection was E. coli No. TP-85; the most avirulent were E. coli No. 727 and E. coli No. D616. The isolates selected by us showed the following results: the most virulent were E. coli 22/20, E. coli 3/16, E. сoli 20/20, E. coli 24/21 – E. coli 7/16, E. coli 19/2, E. coli 18/20, E. coli 9/17, E. coli 5/16, E. coli 28/21, E. coli 29/21. Avirulent were the isolates E. coli 25/21 and E. coli 17/20. LD50 for them was 22,36 × 108. The study of museum strains of E. coli isolates compared with the isolates obtained in the Moscow and Tula regions led to the conclusion that during long-term storage of collection strains, their virulence decreases. The tendency of strains to lose their physicochemical properties (stability) during lyophilization has also been noted. There could be several reasons for this: imperfect control and storage at different stages of the culture life cycle; improper lyophilization drying when strains were not deep-frozen; and failure to follow drying steps, which over time led to a change in the genetic structure of the strain.
Evaluating the effect of soil moisture during sowing on the depth of cereal crops seeding
Authors: Yakovlev D. A. , Belyaev V. I. , Polyakov G. N.
Published: February 2023

Evaluation of the depth of seeding cereal crops after sowing by units equipped with tyne coulters and tine cultivators under different soil moisture conditions in the steppe zone of Siberia is given. The studies were conducted from 2018 to 2021 in the steppe zone of the Altai Territory. Soil moisture was determined using an HH-2 electronic moisture meter from Delta-T Devices, the principle of operation of which is based on measuring the electrical conductivity of the soil. The depth of seed placement was determined by the etiolated (clarified) part of the plants. When comparing the results, the value of standard deviations from the average value of seed placement depth was taken, because according to the principle of evaluation it corresponds to the agrotechnical requirements for sowing. The standard deviations from the seed placement depth after sowing by the machines equipped with tyne coulters and tine cultivators found in the soil moisture range from 12 to 40% were analyzed. Standard deviations from the average defined seed placement depth are summarized in scatter diagrams. All deviations from the depth of placement after sowing with these coulters were within the acceptable limits of changes in agrotechnical requirements, which are ± 10 mm. The relationship between deviations from the average depth of seeding and soil moisture at the time of sowing was established. Relationship equations of these indicators are highly significant, as evidenced by high coefficients of determination. These equations will allow agricultural producers of the steppe zone of the Altai Territory with knowledge of soil moisture at the time of sowing to predict its quality component after sprouting, since the uniformity of seed distribution on the depth of seeding affects the crop yield.
Results of symbiotic breeding of alfalfa
Authors: Stepanova G. V.
Published: February 2023

The results of the studies on the effectiveness of alfalfa symbiosis varieties created by different methods are presented. Some peculiarities of plant-rhizobial interactions are identified. When alfalfa was grown in low- and near-neutral soils (pH 5.1-6.0), the highest increase in dry matter yield was achieved by pre-sowing inoculation with the CXM 412b strain, and on strongly and moderately acidic soils (pH 4.1-5.0) by the CXM 404b strain. In the year of sowing, the efficiency of symbiosis was at least 25%, and the yield reduction to the control level occurred during 3-4 years of use. Strain СХМ 404b has the unique ability to increase the seed productivity of different varieties under different growing conditions by 23-56%, other strains - by 3-32%. It was found that the productivity of variety microbial systems is mainly determined by the strain of nodule bacteria (the effect of inoculation was 60-62%). No relationship between the yield of the aboveground biomass and its crude protein content was found. The correlation coefficients obtained in the different field experiments were -0.41 ± 0.34 to 0.26 ± 0.39. Pre-sowing inoculation with highly active rhizobia strains of alfalfa variegated seeds of Selena, Agnia, Taisia, created using the methods of conjugate symbiotic breeding, increased the yield in the year of sowing by 26-35% in dry matter and by 44-56% in seeds. The yield of Vega 87, Lugovaya 67, Pastbishnaya 88, and Nakhodka varieties created by traditional methods increased by 3-20% in dry matter and by 23-29% in seeds. Pre-sowing inoculation with active rhizobia strains of alfalfa cultivars created by symbiotic breeding methods increased the yield in the first year of use by 46-128% in plots where alfalfa was not grown before and by 32-35% in the crop rotation with high alfalfa crop saturation.
Efficiency and competitive ability of festulolium mixed with alfalfa when grown for feed
Authors: Bakshaev D. Yu.
Published: February 2023

The results of yield analysis and biological efficiency of joint cultivation of festulolium and alfalfa with different methods of sowing and nitrogen fertilizers in the forest-steppe zone of Western Siberia are presented. The joint sowing of festulolium with alfalfa at different alternation of rows reduces the yield of green mass by 8.9-15.1% compared to the single-seeded festulolium sowing. Nitrogen application at a dose of 30 kg/ha significantly increased the yield of festulolium mixtures with alfalfa in the variants of inter-row sowing by 21.2% and in the variant of sowing by seed mixture by 20.2% due to the increase of shoots on festulolium plant by 11.1%, and the shoot weight - by 12.5-17.8%. An increase in nitrogen dose to 60 kg/ha significantly increased the yield of festulolium 16.13 t/ha green mass (74.1%) compared with unfertilized background due to an increase in the number of shoots on the plant by 26.6% and an increase in weight per shoot by 30.1%. There was a 21.0-30.2% decrease in the number of shoots of the cereal component in the mixtures and a 76.7-82.1% decrease in the number of shoots of the legume component. At the same time, the shoot mass of festulolium increased by 8.3-42.5%, while that of alfalfa decreased by 54.3-81.5%, indicating its depression. Land equivalent ratio (LER) is higher in the variants with the application of fertilizers. With no nitrogen use, the major share of the factor belongs to festulolium. With the application of small doses of nitrogen, the impact of the legume component increases through increased competitive ratio (CR). At the same time, a positive value of the coefficient of aggressivity (CA) was noted in the cereal component, which characterizes it as the dominant species.
Biological and molecular genetic properties of Trichophyton benhamiae, a new pathogen of dermatomycoses in cats
Authors: Smagulova A. M. , Kukhar E. V. , Glotova T. I. , Glotov A. G.
Published: February 2023

The results of isolation of two strains OVB_T. b-19 and OVB_T. b-20 of a new microscopic fungus species Trichophyton benhamiae from the samples of biological material from cats with clinical signs of dermatomycosis are presented.This type of fungus was isolated from domestic cats for the first time in Russia. Molecular genetic studies, species identification and determination of the properties of the isolated cultures were carried out using approved methodological recommendations and determinants of pathogenic and opportunistic fungi. The keratinolytic and biochemical activity, cultural-morphological (phenotypic) and molecular-genetic properties of T. benhamiae were studied. Both strains of the fungus were characterized by a variety of phenotypic properties: they formed colonies on the nutrient media that differed in morphology and color of aerial and substrate mycelium. They revealed the similarity of micromorphology: the presence of a septate bamboo-like mycelium with characteristic branching of two-layer macroconidia and microconidia. The studied strains were characterized by similar biochemical properties (pronounced saccharolytic and urease activities) and keratinolytic activity. The identified keratinolytic activity of the T. benhamiae strains indicates their etiological role in the development of dermatomycoses in domestic cats. The phenotypic characteristics fully corresponded to the culture of the microscopic fungus T. benhamiae. Molecular genetic studies revealed that microscopic fungi isolated from cats belonged to the genus Trichophyton, species Benhamiae. Molecular genetic studies established that the sequences of OVB_T. b-19 and OVB_T. b-20 strains that had been obtained were identical. Both strains are listed in the GenBank database with individual numbers in the international NCBI database, ON479483 and ON479484.
The method of increasing the resistance of young cattle
Authors: Kuzmina I. Yu.
Published: February 2023

In the conditions of the Magadan region researches on the use of a feed additive based on seaweeds (Laminaria Bullatelancet-likelargekelp, fucus Fucusevanescens C. Agardh) in combination with lichens (Cladonia alpestris and Cetraria islandica) in the diets of young cattle of mixed cattle were conducted. Experimental and control groups of 15-17-month-old young animals were matched by the pairwise method. The groups included first-generation crossbred Hereford and Aberdeen Angus steers. Young animals of the experimental group received daily feed supplement in addition to the basic diet: kelp in an amount of 120 g/head with lichens 50 g/head/day. The stimulating effect of the supplement on the body is due to the content of a wide range of biologically active substances that are a factor in the growth and development of farm animals and have a positive effect on their immune system. Inclusion of the feed additive into the diets increased the absolute weight gain of the experimental bulls by 5,62 kg, the relative gain by 12,53%, and the average daily gain by 93,8 g (12,55%) as compared to the control bulls (p ≤ 0,001). The relative growth rate according to S. Brody was 1.31% higher in experimental young animals from birth to 17 months of age compared to the control. The use of the feed additive improved the physiological condition and resistance of the young animals of the experimental group. The content of erythrocytes in their blood increased by 0.32 million/μL (5.18%), hemoglobin by 1.1 g/dL (11.48%), and calcium by 0.06 mmol/L (2.37%).
The opportunities of using a natural adaptogen from the Galleria mellonella larvae in veterinary medicine
Authors: Osokina A. S. , Mikheeva E. A. , Maslennikov I. V.
Published: February 2023

A comparative analysis of the adaptation effects of the Porsolt test of fractionated solutions obtained from the products of the larvae of the large wax moth (Galleria mellonella) on biological systems was performed. The method of X-ray photoelectron spectroscopy determined that in the obtained light fraction of the products of larval life there is a high-energy component of N1s spectra (~402.0 eV) and bond energy for carbon in the C-N bond (~286.0 eV), which indicates the presence of protonated amino groups in the samples. Absorption at 1700 cm-1 can be attributed to the presence of dicarboxylic amino acids (glutamic and aspartic) and other organic acids, which are much less in the heavy fraction. During oral administration of the studied extracts, their multidirectional effect on the intestines of laboratory mice was found. The negative effect of heavy fraction on the microbiocenosis of the intestine by the qualitative composition of the microflora was detected. When the light fraction is used, the intestinal microflora is close to the control. Analysis of the number of leukocytes of the small intestine when the fractions were injected reflected the local immune response of the body. The content of these cells on the mucosal plate of mice injected with the lung fraction was 67.2% higher than that of the control mice (p ≤ 0.05). The content of leukocytes on the own plate of the mucosa of mice injected with the heavy fraction was 2.7 times higher compared to the control, indicating an inflammatory reaction. The difference between the experimental groups is significant (p ≤ 0.001). The comparative effect of the fractions showed that their oral administration had a different effect on the swimming time compared to the control. After 20 days of the experiment, mice injected with the heavy fraction had significantly increased their swimming time compared to the first day (p ≤ 0.05). However, a negative adaptogenic effect compared to the control group is noticeable. A significant difference was found between the results on the 30th day between the experimental groups, which indicates a pronounced difference in the results obtained.
Relations Between Gender and Science-Technology in Brazilian Science Teaching: What do Researches Say?
Authors: Butzen Hendges Ana Paula , Ayres dos Santos Rosemar
Published: February 2023

Through discourses constructed in historical, cultural and social contexts, women face difficulties regarding the insertion, permanence and ascension in the scientific-technological career. In this context, we aim to understand and analyze what is shown in research on gender issues and Science-Technology (ST) in science education in Brazil. To do so, we present a qualitative research, a state of the art, which had as corpus of analysis theses and dissertations present in the repository of the Brazilian Institute of Information in Science and Technology. Methodologically, we used the Textual Discourse Analysis, from which three categories emerged, namely: (1) The discourse of women's non-belonging in ST (2) The (in)visibility of female models who did/do ST and (3) Scientist-mothers and the multiplied workdays. We realize that the feminine gender faces stereotypes and prejudices that end up influencing its inclusion and path in ST. In the search for making ST visible and showing it as a possible career for the female gender, family, school, teachers, and the promotion of public policies of support and incentive are some of the essential means for this.
Analisis Perbandingan Algoritma AES Dan RC4 Pada Enkripsi dan Dekripsi Data Teks Berbasis CrypTool 2
Authors: Fitriana Risa Naili , Djuniadi Djuniadi
Published: February 2023

Berkembangnya teknologi diikuti dengan bertambahnya data yang cukup besar. Data tersebut tidak semuanya disajikan untuk khalayak umum, beberapa data sangat dijaga kerahasiannya karena kepentingan tertentu. Penelitian ini bertujuan untuk melakukan uji coba enkripsi dan dekripsi pada data teks (dengan  format  *.txt)  untuk menjaga kerahasiannya dan membandingkan kinerja dari algoritma AES dengan RC4. Penelitian ini menggunakan metode algoritma AES dan RC4 dengan panjang kunci 256 bit menggunakan CrypTool 2  untuk proses enkripsi dan dekripsi. Hasilnya uji coba pertama yaitu dilakukan uji coba enkripsi dan dekripsi algortima AES pada data teks menghasilkan ukuran ciphertext yang berbeda dari data teks asli. Sedangkan uji coba kedua dilakukan enkripsi dan dekripsi algoritma RC4 pada data teks dihasilkan ukuran ciphertext yang sama sebelum dilakukan proses simulasi. Sehingga dari penelitian ini diperoleh algoritma RC4 menghasilkan ukuran ciphertext lebih kecil dari pada menggunakan algoritma AES.
Analisa dan Perancangan Aplikasi Marketplace Bagi Pelaku UMKM Untuk Pemulihan dan Kebangkitan Ekonomi di Indonesia Pada Masa Pandemi Covid-19
Authors: - Himawan , Paulina Kristin , Ridwan Fauzi Aditya
Published: February 2023

Pandemi Covid-19 yang melanda di hampir seluruh negara dan tidak terkecuali di Negara Indonesia, menyebabkan dampak yang sangat besar terutama pada bidang ekonomi, pendidikan, kesehatan dan sosial. Banyak negara mengalami keadaan krisis yang luar biasa dikarenakan pandemi Covid-19 yang cukup lama berlangsung. Salah satu contoh dari efek yang sangat dirasakan oleh hampir seluruh masyarakat dunia dengan adanya pandemi Covid-19 adalah di bidang ekonomi, hal ini dibuktikan dengan sudah tidak terhitung lagi jumlah bidang usaha yang mengalami krisis dan bahkan berujung dengan kebangkrutan. Namun demikian, melihat kepada situasi dan realita kehidupan tersebut, para pelaku usaha mulai memikirkan untuk memanfaatkan serta mengoptimalkan penggunaan media digital, media teknologi informasi dan juga media sosial. Hal tersebut perlu dilakukan oleh para pelaku UMKM untuk secara bertahap melakukan transformasi dari bentuk usaha yang sebelumnya menggunakan model konvensional menjadi model digitalisasi. Penelitian ini mengajukan model perancangan platform aplikasi marketplace yang dapat digunakan sebagai media bagi para pelaku UMKM yang tergabung sebagai anggota Koperasi UMKM Indonesia Sejahtera (KOMINDO) untuk dapat memasarkan dan menjual berbagai produk yang dihasilkan oleh masing-masing anggota KOMINDO.
Educational Data Clustering Menggunakan K-Means pada Seleksi Penerimaan Peserta Didik Baru Madrasah Aliyah Negeri Unggulan
Authors: Wahyudi Noor , Ardilla Yunita , Hastuti Nanik Puji
Published: February 2023

The National Students admissions (SNPDB) for Madrasah Aliyah is managed by the Directorate of Madrasah Curriculum, Facilities, Institutions and Student Affairs. It is essential for the Directorate and Madrasah to explore patterns and knowledge from admission data in formulating policies and programs from to MAN. Educational Data Clustering (EDC) is a data mining method that is implemented in the education area. K-means is applied to group students based on the results of learning potential and academic potential tests that will be used for development program and student admission policies at MAN-IC. The best results from the experiments tested with Silhouette dividing the data into 2 clusters are excellent and good. The Silhouete value indicates the cluster structure in the medium predicate.. The results present the distribution of clusters in 23 MAN-IC, distribution of personality profiles of prospective students, as well as recommendations for conducting tests in Madrasah.
ANALYSIS OF WIRELESS AND CABLE NETWORK QUALITY-OF-SERVICE PERFORMANCE AT TELKOM UNIVERSITY LANDMARK TOWER USING NETWORK DEVELOPMENT LIFE CYCLE (NDLC) METHOD
Authors: Naim Farras , Saedudin Rd. Rohmat , Hediyanto Umar Yunan Kurnia Septo
Published: February 2023

There are some infrastructure problems in the Telkom University Landmark Tower building, which still lacks human resources to help troubleshoot the network when an interference happens. The second problem is that the TULT has a closed concept building, which will be an issue for the network stability. The last problem is the lack of information transparency when handling a network problem. In this research, the author uses the NDLC (Network Development Life Cycle) method as a step to solve the problem. The sequence of the NDLC methodology starts from the initial stage, the analysis stage, the design stage, the prototype simulation stage, and the final stage. Based on the analysis of the current wireless and wired network condition, it can be concluded that it is still in good condition, which only requires good and scheduled maintenance to prevent the internet connection from going down. The current wireless and wired connections are tested during peak and free times by adjusting the lecture conditions with the Hybrid Blended Learning (HBL) learning model, where not too many people use the internet connection from TULT building. Tests on wireless and cable networks during peak and off-peak hours revealed results for the 4th, 8th, 9th, and 18th floors with a very good delay index, a very good throughput index, and a very good packet loss index on all floors. All wireless and wired network test results have a very good index category
ANALYSIS OF THE IMPLEMENTATION OF MVVM ARCHITECTURE PATTERN ON PERFORMANCE OF IOS MOBILE-BASED APPLICATIONS
Authors: Indrawan Deri , Kusumo Dana Sulistyo , Puspitasari Shinta Yulia
Published: February 2023

Performance efficiency is important in mobile application development because mobile devices have limitations in terms of power and resources. Performance efficiency can be improved by applying architecture patterns. In this paper, we use the Model View ViewModel (MVVM) architecture. The application of the architecture is carried out to analyze how practical the application of the MVVM architecture pattern is in increasing performance efficiency in the mobile application. Performance efficiency is measured based on CPU usage, memory usage, and execution Time. The case study shows that the CPU usage and execution Time on MVVM are smaller than Base architecture pattern from the AR Ruler. This is due to the third-party library RxSwift in the MVVM architecture that increases the application's response so that CPU usage and execution time is better than Base architecture pattern. However, the existence of the third-party library RxSwift has a negative impact on memory usage, resulting in higher memory usage than the Base Architecture Pattern. The MVVM pattern is highly recommended for mobile application development to improve performance efficiency.
IT RISK MANAGEMENT ANALYSIS ON BANK XYZ E-BANKING SERVICE SYSTEM USING ISO 31000
Authors: Ash Siddiqi Hafiz Izzamufid , Darwiyanto Eko , Priyadi Yudi
Published: February 2023

The growth of information technology is now forcing businesses to innovate, one of which is in the banking sector. Electronic banking or e-banking is a new system in the banking world, where the existence of e-banking can make it easier for customers to carry out banking activities. Bank XYZ has also used this e-banking service system where the services are Mobile Banking, Personal Internet Banking, Corporate Internet Banking. but there are several risks that may occur ranging from low to high level risk. The purpose of this research is to carry out a risk assessment using the ISO 3100 risk management standard on the e-banking application of Bank XYZ. The results show that there are 20 possible risks that occur and are divided into two categories, namely those that may occur from outside and from within the company. Risk analysis shows that risk has several types of impacts from small scale to disaster scale. There are also several types of risk management depending on the type of risk and the priority level of the risk, namely risk avoidance, risk sharing, risk mitigation, and risk acceptance.
REDESIGNING USER INTERFACE OF TEMAN BUS APPLICATION USING GOAL-DIRECTED DESIGN
Authors: Prastiawan Yogi Putra , Effendy Veronikha , Herdiani Anisa
Published: February 2023

In these modern era, it is very easy to create an investment portfolio, an investment portfolio can be formed by buying a shares. By creating portfolio investation, our can expect score return which makes it an advantage. However, there is also a risk value that will be obtained when buy shares. In the formation of an investment portfolio for active investors, it is expected to create an optimal investment portfolio, there are many models that can be used to create an optimal investment portfolio. In this final project, will discusses the use of the Black-Litterman Model in optimizing portfolios for active investors. The Black-Litterman model is one of the models that can be used to optimize the investment portfolio, the Black-Litterman model provides additional information for the return and risk values based on the views of experts. This model builds on the MV and CAPM using a Bayesian framework that allows investors to effectively incorporate their views of the market into the allocation process asset. Based on several tests that have been carried out during the research with different days, the value of the investor's view will always be different every day, the value of an optimistic view will have a good impact on the stock, even though the stock price is falling, if the investor's view is expressed optimism, the weight of the shares will remain high.
USE OF THE BLACK-LITTERMAN MODEL IN PORTFOLIO OPTIMIZATION FOR ACTIVE INVESTORS ON STOCKS IN LQ45 INDEX
Authors: Herlansyah Ridhwan Rifky , Saepudin Deni
Published: February 2023

In these modern era, it is very easy to create an investment portfolio, an investment portfolio can be formed by buying a shares. By creating portfolio investation, our can expect score return which makes it an advantage. However, there is also a risk value that will be obtained when buy shares. In the formation of an investment portfolio for active investors, it is expected to create an optimal investment portfolio, there are many models that can be used to create an optimal investment portfolio. In this final project, will discusses the use of the Black-Litterman Model in optimizing portfolios for active investors. The Black-Litterman model is one of the models that can be used to optimize the investment portfolio, the Black-Litterman model provides additional information for the return and risk values based on the views of experts. This model builds on the MV and CAPM using a Bayesian framework that allows investors to effectively incorporate their views of the market into the allocation process asset. Based on several tests that have been carried out during the research with different days, the value of the investor's view will always be different every day, the value of an optimistic view will have a good impact on the stock, even though the stock price is falling, if the investor's view is expressed optimism, the weight of the shares will remain high.
PENERAPAN METODE DOUBLE EXPONENTIAL SMOOTHING DAN VISUALISASI DASHBOARD UNTUK MENGANALISA DATA TRANSAKSI PENJUALAN PADA KEMITRAAN PT NATURAL NUSANTARA (STUDI KASUS : STOCKIS BG.3005 MUARA ENIM)
Authors: Tasriq Tasriq , Kunang Suzi Oktavia
Published: February 2023

Stockis BG.3005 adalah salah satu kemitraan PT Natural Nusantara yang terletak di Muara Enim yang mengalami kesulitan dalam mengetahui tren penjualan dan manajemen stok barang. Oleh karena itu, dilakukan penerapan metode BI roadmap dalam membangun dashboard business intelligence untuk mengevaluasi penjualan produk serta metode double exponential smoothing yang digunakan untuk meramalkan penjualan pada Stockis BG.3005 Muara Enim. Penerapan metode BI roadmap didapatkan hasil berupa dashboard yang menampikan penjualan dan pendapatan tahun 2020 – 2021 yang mengalami penurunan, kategori produk terlaris (kosmetik dan perawatan tubuh, rumah tangga, kesehatan, dan agrokompleks), 5 produk yang paling banyak peminat (Pasta Gigi Nasa, Moreskin : Clean Glow Cream, Grece Anti Perspirant, Quwless : Liquid Hygiene For Man dan Shanas : Shampoo 3 in 1). Serta peramalan penjualan menggunakan metode double exponential smoothing dengan menggunakan ,  yang menghasilkan MAD atau tingkat kesalahan terkecil adalah  dengan hasil peramalan untuk tahun 2022 bulan Januari yaitu, Pasta Gigi Nasa = 33 item, Moreskin : Clean Glow Cream = 2 item , Grece Anti Perspirant = 3 item, Quwless : Liquid Hygiene For Man­ = 2 item, dan Shanas : Shampoo 3 in 1 = 4 item. Dashboard Business Intelligence yang dihasilkan telah memudahkan Stockis BG.3005 Muara Enim dalam mengetahui tren dan peramalan penjualan.
PENJADWALAN RUANG OPERASI RUMAH SAKIT DENGAN METODE NON-DOMINATED SORTING GENETIC ALGORITHM II (NSGA-II)
Authors: Mahariani Yeni Roha
Published: February 2023

Penjadwalan operasi pasien merupakan aktifitas penting pada kegiatan operasional rumah sakit, karena menentukan waktu pasien-pasien tertangani dengan baik. Permasalahan ini dimodelkan sebagai masalah optimasi multi-obyektif yaitu meminimalkan waktu yang digunakan saat tindakan operasi. Masalah penjadwalan operasi dirumuskan sebagai masalah mixed integer programming (MIP), sehingga variabel merepresentasikan jadwal kasus operasi yang layak untuk ruangan tertentu dalam satu hari. Tahapan dalam merumuskan solusi heuristik, yaitu menentukan fungsi objektif sebagai solusi fraksional, menentukan solusi integer dengan mengubah solusi fraksional, dan meningkatkan kualitas solusi menggunakan local branching, formulasi MIP tersebut didasarkan pada variabel time-index. Model optimasi penjadwalan pasien dapat diselesaikan dengan metode berbasis global search. Metode tersebut dapat menghasilkan sejumlah jadwal operasi non-dominated yang mendekati pareto front dalam satu proses. Walaupun mampu mendekati pareto front, isu utama dari metode berbasis global search adalah bagaimana menjaga diversitas jadwal operasi. Penelitian ini menerapkan algoritma Non-dominated Sorting Genetic Algorithm II (NSGA-II). Berdasarkan hasil uji coba, dalam hal isu diversity pada penjadwalan operasi, metode NSGA II mampu menghasilkan himpunan pareto optimal dengan tingkat diversitas terbaik sebesar 0.597. Hal ini menunjukkan bahwa metode usulan berbasis NSGA-II mampu menghasilkan jadwal operasi pasien yang beragam dengan berbagai kombinasi.
Characterization of M-curcumin complexes (M= Cu, Co, Ag) in turmeric rhizome as sensitizer candidates in dye-sensitized solar cell (DSSC)
Authors: Jariah Ainun , Hadisaputra Saprizal , Purwoko Agus Abhi
Published: February 2023

This experimental research aims to characterize the complex compound M-curcumin (M=Cu, Co, Ag) based on turmeric (Curcuma longa Linn) rhizome as a candidate for photosensitizer in solar cells. The basic material used for manufacturing the M-curcumin complex compound in this study was curcumin from turmeric rhizome extract added to Cu2+, Co2+, and Ag+ metal ions. The results of the synthesis of the M-curcumin complex were characterized by FTIR and Uv-Vis spectrophotometers. The FTIR spectrophotometer test showed a curcumin compound in the viscous curcumin extract, characterized by an absorption wave number corresponding to the curcumin compound. In the M-curcumin complex, the bond between the metal and the ligand only appears in the Co-curcumin complex at the absorption number of 498.77 cm -1. The results of the UV-Vis spectrophotometer test showed that the maximum wavelength absorption in curcumin extract was 430 nm (abs = 0.688), Cu-Curcumin complex lmax 300 nm (abs = 2.573), Co-curcumin complex lmax 425 nm (abs = 1.067), and complex Ag-Curcumin lmax 430 nm (abs = 1.36). The UV-Vis and FTIR characterization showed that the Co-curcumin complex has good potential compared to the organic compounds (curcumin) and can be used as an alternative photosensitizer in solar cells
Intervenção fisioterapêutica na reabilitação funcional da entorse lateral de tornozelo em atletas
Authors:   , Santos Sabrina Macedo Verissimo e , Jorge Adriana Caldeira
Published: February 2023

A entorse de tornozelo é um movimento brusco atingindo a região do retropé, afetando diretamente os ligamentos, classificada como a lesão musculoesquelética com maior incidência entre atletas. A estimulação transdérmica, liberação do ponto de gatilho, exercícios para ganho de força e estabilidade articular, alongamento e RPG serão alguns dos recursos terapêuticos utilizados pelo fisioterapeuta para reabilitar e reduzir os danos musculoesqueléticos causados por lesões devido à exercícios excessivos, extenuantes e repetitivos. Objetivo: Esse estudo tem como finalidade evidenciar a importância da fisioterapia desportiva no processo de reabilitação e prevenção de lesões em atletas. Metodologia: O presente trabalho foi desenvolvido através de uma revisão bibliográfica descritiva da lesão e a conduta fisioterapêutica, no qual foram utilizadas bases de dados Bireme, Scielo, Medline e Pedro, livros relevantes. Resultado: A partir da busca nas bases de dados para esse estudo, foram selecionados 14 artigos de acordo com os critérios de inclusão e exclusão. Conclusão: O estudo pode concluir que o treino proprioceptivo é o método de tratamento mais eficaz para tratamento da entorse de tornozelo, entretanto outras técnicas como: Kinesio Taping, PRICEMMMS, TENS e Terapia Manipulativa podem auxiliar e intensificar o tempo de recuperação.
SWOM strategy and influence of its using on developing mathematical thinking skills and on metacognitive thinking among gifted tenth-grade students
Authors: AlAli Rommel , Wardat Yousef , Al-Qahtani Mohammed
Published: February 2023

Education is important for the advancement of peoples and countries, so it is necessary to take care of the learners by providing them with the skills and experience to face problems systematically based on sound thinking, by following appropriate teaching strategies. Therefore, this study aimed to use the school wide optimum mode (SWOM) strategy to reveal its effect on meta-cognitive thinking, and the effect of its employment in developing the mathematical thinking skills of gifted tenth-grade students. The analytical descriptive approach and the experimental approach were used. 84 gifted male and female students from the tenth grade were randomly selected. The data were analyzed using SPSS and evaluated according to the Rasch model. The study results showed that there were statistically significant differences between the average level of metacognitive thinking among gifted students who learned using SWOM strategy, and the average level of metacognitive thinking among students who learned traditionally, in favor of the students who learned using SWOM strategy. The results of the study also showed that there were statistically significant differences between the average scores of gifted students who learned using SWOM strategy, and the average scores of gifted students who learned traditionally in a mathematical thinking skills test, in favor of the students who learned using SWOM strategy.
Successful treatment with minocycline and Saiko-keishi-to for COVID-19
Authors: Ohe Masashi , Shida Haruki , Yamamoto Junya , Seki Masahide , Furuya Ken
Published: February 2023

N/A
Entropy generation in unsteady MHD convective flow past a flat porous oscillating plate with suction or injection
Authors: Akpabokigho L Panya  , Olufemi A Akinyemi  , Akindele M Okedoye
Published: February 2023

In this study, Entropy generation in MHD convective flow past a flat porous oscillating plate with suction or injection are presented for an unsteady, one-dimensional flow of a viscous incompressible fluid. The importance of Entropy generation is noticed in industrial and scientific fields including heat transfer in thermal systems which includes viscous dissipation, chemical reaction, mass transfer, heat transfer, and electrical conduction etc. The role of flow parameters like magnetic parameter, Radiation parameters, Grashof number, Heat generation/absorption, irreversibility distribution ratio on entropy generation are presented and elaborated through graphs. The obtained results reveal that for various values of Hartmann number, the entropy generation and Bejan number are increased, a larger radiation parameter increases the entropy generation and the Entropy generation due to viscous irreversibility decreases with the increase in Grashof number and Hartmann number.
Imatinib mesylate: Recent drug used in oncology
Authors: Nerella Bhavani  , M Sunitha Reddy
Published: February 2023

Background: The European Union and Canada have approved generic imatinib for the treatment of chronic myeloid leukaemia (EU). Anecdotal evidence suggests that generic imatinib performs less well than brand-name imatinib. MEDLINE and EMBASE were searched as methods. The European Medicines Agency (EMA) and Health Canada-approved generic imatinib product monographs were examined. We contacted Novartis, Teva, and Apotex's medical information. Results: A number of issues have been brought up. First, generic imatinib approved outside of Canada and the EU has been linked to inconsistent results in two case series and lower efficacy in minor case reports. However, it is unclear whether these generic products' clinical bioequivalence has been established. Second, there have been concerns raised about generic imatinib's use in different populations. However, compared to adults with chronic myeloid leukaemia, imatinib absorption is not significantly different in children with chronic myeloid leukaemia or in patients with gastrointestinal tumours. Even though there have been reports of reduced absorption following gastric bypass and gastrectomy, the majority of imatinib is absorbed in the ileum, duodenum, colon, and jejunum. It has also been demonstrated that changes in stomach acidity have no impact on imatinib absorption. At room temperature, the beta-crystal form of brand-name imatinib is more stable than the alpha-crystal form of generic imatinib. However, the EMA discovered that both crystal forms were extremely soluble and that polymorphism would not materially affect the efficacy of generic imatinib.
Determination of glutathione peroxidase activity and oxidized/reduced glutathione ratio in patients with colon cancer
Authors: GÖKCE Kemal  , DAG Seker
Published: February 2023

Colon cancer (CC) is accepted as the third type of cancer that causes death in the world. Oxidative stress and low glutathione peroxidase (GPx) activity can cause CC. This study aims to show whether GPx and Oxidized (GSSG)/ reduced glutathione (GSH) levels, which are considered oxidative stress markers, are effective in the etiopathogenesis of CC. Erythrocyte isolation was performed in 3 ml blood sample taken from volunteers aged 18-75 years. Hemoglobin amounts were determined from the standard graph drawn by monitoring the conversion of methemoglobin to cyanmethemoglobin in the presence of cyanide at 540 nm. Glutathione peroxidase activity was determined by spectrophotometric monitoring of NADPH+H+ (reduced nicotinamide adenine dinucleotide phosphate) oxidation at a wavelength of 340 nm. The amounts of oxidized and reduced glutathione were determined by using the standard graph drawn by following the 412 nm wavelength of the formation of 2-nitro-5-thiobenzoic acid, which has a yellow color. GPx activity of individuals with CC is 5.64 ± 1.49 U/gHb, GSH concentration is 6.96 ± 1.45 nmol/gHb, and GSH/GSSG ratio is 1.04 ± 0.49, GPx activity of healthy individuals is 10.52 ± 2.22 U/gHb, GSH concentration 11.43 ± 1.90 nmol/gHb, and GSH/GSSG: 3.86 ± 1.30, that is, the values of the patient group were significantly lower than the control group. Current results suggest that GPx activity, GSH concentration and GSH/GSSG ratio can be used as CC markers in the diagnosis and monitoring of disease course, and that the decrease in these parameters may be associated with an increased risk of CC.
Antimicrobial and antioxidant potentials of crude extracts of culturally dissimilar endophytic fungi
Authors: Ugochukwu M Okezie  , Michael C Obi  , Ugonna C Morikwe  , Ijeoma N Ebenebe  , Miriam GU Nwaneri
Published: February 2023

Endophytes from an unexplored plant such as Spatterdock (SD) Nuphar lutea variegata could be a dependable producer of novel secondary metabolites active against drug resistance organisms. This study explored the diversity of fungal endophytes from mid-rib (MR) and leaf blade (LB) of Nuphar lutea variegata as well as the antimicrobial and antioxidant potentials of their secondary metabolites. Morphological features observed showed four species were isolated. A broad-spectrum antimicrobial activity observed to be concentration-dependent was observed for all the fungal crude extracts 1 mg/mL. Crude extract of SD-LB3 showed the best antibacterial activities against S. aureus and P. aeruginosa with a minimum inhibitory concentration of 0.5 and 0.25 µg/mL respectively. The antioxidant capacities of the fungal crude extracts showed a better neutralizing effect of free radicals compared to the standard Quercitin. Effective inhibition of free radicals was observed for all the fungal extracts from 20 to 100 mg/mL (96.7 – 99.3 %). The highest antioxidant activity was shown by the extracts of fungi isolated from the leaf blade with an average of 98 to 99.2 % at the tested concentrations of 20 to 100 mg/mL. Our study provides evidence of diverse endophytic fungi associated with Nuphar lutea variegata, and the antibacterial and antioxidant activities observed confirm their capacities as producers of bioactive secondary metabolites. This study is the first to isolate endophytic fungi form Nuphar lutea variegata and screen the antimicrobial and antioxidant activities of their secondary metabolites.
Natural honey and diabetic wound healing: A review of literature
Authors: Ofor Casimir Chijioke  , Ramalan Mansur Aliyu  , Ohanme Eugene Ohams  , Anele Donatus Onyebuchi  , Ajegi Innocent Fountain  , Nwakelu Benjamin Nwaforcha
Published: February 2023

Honey has been used widely for the treatment of various types of chronic burns, necrotic diabetic foot and post-operative split skin wounds. Despite the fact that wounds in diabetic patients are similar to wounds in normal patients, the healing process is different from that of other wounds. The most worrisome aspect of diabetic wounds is that the healing process is unduly prolonged. Poor oxygenation of tissues occurs in diabetic wounds and is caused by early inflammatory responses and a heavy load of Reactive Oxygen Species (ROS) induced by high blood sugar levels in diabetic patients. The formation of advanced glycation end-products (AGEs) under severe hyperglycemic conditions and interaction with their receptors (RAGE) are also known to impair wound healing among diabetic patients. The antioxidant, anti-inflammatory and antibacterial effects of natural honey significantly promote the healing process in diabetic wounds. This is due to the presence of hydrogen peroxide (H2O2) produced by the action of glucose oxidase on glucose in the honey, nitric oxide and the hyperosmolar nature of natural honey. Honey also stimulates angiogenesis in the wound environment thereby enhancing wound healing in diabetics. The potent antioxidants in natural honey include, phenolics, flavonoids, ascorbic acid and certain enzymes such as catalase. Glucose oxidase from the bee crop slowly breaks down glucose into gluconic acid, which lowers the pH of honey, and the presence of hydrogen peroxide helps to kill bacteria in diabetic wounds. In a wound site, the lower pH of honey (3.5–4) reduces protease activity, increases oxygen release from hemoglobin, and stimulates the activity of macrophages and fibroblasts, while the hydrogen peroxide content sterilizes the wound and stimulates vascular endothelial growth factor (VEGF) production.