bluuebunny/crossref_metadata_2025 huggingface dataset:
Validating the Well-being of Older People (WOOP) instrument in China
Authors: Liu Runhua , Mao Zhuxin , Yang Zhihao
Published: October 2022

Introduction:
So far, generic health related quality of life (HRQoL) has been used for estimating utility value, which then be used for calculating quality adjust life years (QALY). HRQoL measures may not capture many of the relevant and important aspects of quality of life other than health. Well-being of older people (WOOP) was first developed in the Netherlands to measure the well-being of older people; this study aims to validate this new measure in China.
Methods:
Between July and August 2022, a cross-sectional study was conducted in a convenient sample of 500 older people in Southwestern China. Consented older people reported their demographic information and the simplified Chinese version of WOOP measure using paper and pencil. The acceptability of WOOP was examined by percent of missing responses. Then, using the data without any missing responses, we examined the acceptability, item responses distributions, pairwise spearman correlations, exploratory factor analysis and known-group validity of WOOP.
Results:
Among the nine items, three of them had more than 10% of missing responses. The response distributions of 9 items in WOOP were overall good without signs of ceiling effects and floor effects. There was not high correlations among WOOP items. A two-factor EFA model suggested WOOP items can be categorized into either internal wellbeing or external wellbeing. Good known-group validity results were found reported.
Discussion:
Some WOOP items may not be easily understood by a small proportion of rural residents. Other results suggested WOOP to be valid instrument for measuring the well-being of elderly in China. The availability of WOOP enables the measurement of wellbeing related utility.
Cardiac Point-of-Care Ultrasound and Multi-Disciplinary Improvement Opportunities in Acute Systolic Heart Failure Management in a Pediatric Emergency Center
Authors: Scott Camille , Alade Kiyetta , Leung Stephanie , Morrison A. Ruthie , Riley Alan F.
Published: October 2022

Background: Cardiac Point-of-care ultrasound (POCUS) has the ability to rapidly assess function and identify systolic heart failure (HF), an often-missed diagnosis. POCUS has the potential to expedite medical intervention, improving overall outcomes. There have been limited studies describing pediatric emergency center (EC) utilization of cardiac POCUS and its impact on outcomes in pediatric patients.
Methods: Authors performed a retrospective chart review at a tertiary children's hospital to identify all patients admitted from the EC to the Cardiac Intensive Care Unit (CICU) with acute systolic HF between January 2017 and August 2019. Outcome measures included EC length of stay (LOS), CICU LOS, and time until first IV HF medicine was administered.
Results: A total of 21 patients and 24 encounters meeting criteria were identified. Cardiac POCUS agreed with standard echocardiography in 8 of 9 cases. Patients who had a cardiac POCUS in the EC seemed more likely to receive their first dose of intravenous heart failure medication while in the Emergency Center (70% vs 43%). There was a trend towards significance, but it did not reach statistical significance (p=0.1). EC and CICU LOS were not significantly different between POCUS and non-POCUS groups.
Conclusion: Cardiac POCUS has the potential to have a valuable role in the early diagnosis of acute systolic HF in children. However, early diagnosis by POCUS did not translate into shorter EC or CICU LOS. This pilot data serves as a baseline for efforts to promote earlier clinical recognition of acute HF and more efficient collaboration between clinical services.
Multiple potentially toxic elements in urban gardens from a Brazilian industrialized city
Authors: Lange Camila Neves , Freire Bruna Moreira , Monteiro Lucilena Rebelo , de Jesus Tatiane Araújo , Reis Roberta Albino , Nakazato Gerson , Kobayashi Renata Katsuko Takayama , Batista Bruno Lemos
Published: October 2022

Urban agriculture should be promoted as long as the food produced is safe for consumption. Located in the metropolitan region of São Paulo-Brazil, Santo André has intense industrial activities and more recently an increasing stimulus to urban gardening. One of the potential risks associated to this activity is the presence of potentially toxic elements (PTEs). In this study, the concentration of PTEs (As, Ba, Cd, Co, Cu, Cr, Ni, Mo, Pb, Sb, Se, V and Zn) was evaluated by soil (n=85) and soil amendments (n=19) in urban gardens from this municipality. Only barium was above regulatory limits in agricultural soil, although enrichment of all elements was observed. A multivariate statistical approach was applied and indicated two groups of elements with strong influence of the petrochemical complex located in this region. However, carcinogenic, and non-carcinogenic risks were not observed. Soil amendments were identified as a possible source of contamination for Ba, Zn and Pb and for pathogenic bacteria. Besides that, the occurrence of antimicrobial resistance suggests some soil management practices are necessary.
Incidence and risk factors of hypertriglyceridemia in males with human immunodeficiency virus who are treated with combination antiretroviral therapy: a retrospective cohort study
Authors: Yu Xian-dong , Huang Huihuang , Jiao Yanmei , Li Jing , Fan Xing , Zhang Dawei , Wang Fu-sheng
Published: October 2022

Background
Hypertriglyceridemia is associated with subclinical atherosclerosis and vascular inflammation even when low-density lipoprotein cholesterol levels are normal. However, few cohort studies have been conducted in males with a higher prevalence of hypertriglyceridemia and higher susceptibility to human immunodeficiency virus (HIV)-related deterioration of arterial structure and function. Our objective was to investigate the incidence of hypertriglyceridemia during treatment with combination antiretroviral therapy (cART) in males with HIV and explore its related risk factors.
Methods
In this retrospective study, we included 309 males living with HIV (median age 31 years [interquartile range 26–42.5]) who initiated cART treatment in our hospital from January 2013 to December 2018. We collected follow-up data on serum triglycerides and other related information as of June 31, 2021. A Cox proportional hazards regression model was used to analyze the related risk factors.
Results
In 666.7 person-years, hypertriglyceridemia occurred in 140 patients (triglyceride ≥ 2.3 mmol/L [200 mg/dL]), and the incidence rate was 21.0 per 100 person-years (The lamivudine [3TC] + tenofovir disoproxil fumarate [TDF] + efavirenz [EFV] regimen accounted for 77.0%.). Multiple Cox regression analysis showed that baseline CD4/CD8 ratio < 0.20 (hazard ratio [HR], 2.705 [95% confidence interval (CI): 1.381–5.296]; P = 0.004}, body mass index (BMI) ≥ 24.0 kg/m2 (HR, 1.768 [95% CI: 1.225–2.552]; P = 0.002), borderline high triglyceride at baseline (HR, 3.457 [95% CI: 2.162–5.527]; P < 0.001), and 3TC + zidovudine (AZT) + EFV regimen (HR, 2.702 [95% CI: 1.593–4.581]; P < 0.001), or 3TC + TDF + lopinavir/ritonavir (LPV/r) regimen (HR, 4.349 [95% CI: 2.664–7.102]; P < 0.001) were independent risk factors for hypertriglyceridemia.
Conclusion
During the course of cART treatment, the incidence of hypertriglyceridemia in males with HIV was high. The main risk factors influencing its occurrence are a low baseline CD4/CD8 ratio, overweight and obesity, and the use of AZT or LPV/r in the cART regimen.
Polyethyleneimine coated MXene quantum dots improve cotton tolerance to Verticillium dahliae by maintaining ROS homeostasis
Authors: Qiu Ping , Li Jiayue , Zhang Lin , Chen Kun , Shao Jianmin , Zheng Baoxin , Yuan Hang , Hu Qin , Ming Yuqing , Liu Shiming , Long Lu , Gu Jiangjiang , Zhang Xianlong , Lindsey Keith , Gao Wei , Wu Honghong , Zhu Longfu
Published: October 2022

Verticillium dahliae is a soil-borne hemi-biotrophic fungal pathogen and inflicts major losses in agricultural production worldwide. Although the pathogenicity of the fungus and plant immunity have been extensively studied, how cotton leaf necrosis is induced by defoliating strains of V. dahliae is poorly understood. In this study, reference-grade genomes were determined for two representative V. dahliae isolates: V991, which is defoliating and aggressive, and 1cd3-2, which is non-defoliating and has weak pathogenicity. Transcriptome analysis showed that cotton resistance to V. dahliae mainly depends on cell wall structure or physical barrier generation in the early stage of infection (3-9 days post inoculation, dpi). However, a large number of pathogenic factors could be detected from 12 dpi and accumulated quickly in cotton stems, accompanied by the burst of reactive oxygen species (ROS), leaf necrosis and defoliation. A V991 specific virulence gene SP3 was identified through comparative genome analysis and found to be highly expressed after colonization. Knock-out of SP3 clearly attenuated pathogenicity, with less ROS produced. These results indicate that disease symptoms in cotton may be due to abnormal immune activation and excessive ROS induced by the pathogen. To further investigate this, Polyethyleneimine coated MXene quantum dots (PEI-MQDs), a type of nano material that possesses the ability to remove ROS in vitro, were used. Cotton seedlings maintain ROS homeostasis with enhanced peroxidase (POD), catalase (CAT) and glutathione peroxidase (GSH-Px) activities after exogenous treatment with PEI-MQDs and show significant tolerance to V. dahliae isolate V991. Our results suggest that excessive ROS and constitutive immune activation in cotton induced by the defoliating strain of V. dahliae is responsible for disease symptoms such as leaf necrosis, and PEI-MQDs application improve cotton tolerance to V. dahliae by maintaining ROS homeostasis.
An epidemiological study on quality of life of beta-thalassaemia major children & its correlates in Kolkata, West Bengal
Authors: Biswas Bijit , Naskar Narendra Nath , Basu Keya , Dasgupta Aparajita , Basu Rivu , Paul Bobby
Published: October 2022

Background & objectives: Quality of life (QoL) of thalassaemic children is likely to be impaired in comparison to their healthy counterparts. Knowledge of attributes affecting QoL of thalassaemic children may help to find out the key areas of interventions to improve it. Thus, the current study was envisioned to find out QoL of beta-thalassaemia major (β-TM) children and its various correlates.
Methods: An institution-based observational study, cross-sectional in design, was conducted in the thalassaemia unit of Calcutta National Medical College and Hospital, Kolkata, West Bengal, India, between May 2016 and April 2017. In the study period, 328 β-TM children and their caregivers were interviewed using a structured schedule.
Results: In the final multivariable logistic regression model, thalassaemic children who were residing in an urban area [adjusted odds ratio (AOR): 3.8 (1.8-7.9)], had mothers with higher educational level (middle and above) [AOR: 2.1 (1.1-4.0)], working parents [AOR: 2.7 (1.2-6.3)], no family history of thalassaemia [AOR: 3.5 (1.6-8.0)], received less number of blood transfusion in the previous year (<12) [AOR: 2.1 (1.1-4.2)], higher pre-transfusional haemoglobin (Hb) level [AOR: 1.7 (1.1-2.6)], no transfusion-transmitted infections [AOR: 2.8 (1.5-5.2)], higher body mass index z-score [AOR: 1.6 (1.1-2.2)] and higher caregivers’ care-related QoL (CarerQoL) score (>5) [AOR: 3.2 (1.6-6.2)] were more likely to have favourable QoL (Peds4QL score >54.3).
Interpretation & conclusions: QoL of the study participants was significantly correlated with their caregiver’s CarerQoL, mother’s educational level, parent’s working status, place of residence, family history of the disease, blood transfusion frequency, pre-transfusional Hb level and nutritional and comorbidity status.
Shelf Life of Greenhouse- and Garden-grown Kale in Nitrogen-enriched and Nonenriched Packaging
Authors: Reda Tony , Thavarajah Pushparajah , Bridges William , Whiteside William , Polomski Robert , Ship Emerson , Thavarajah Dil
Published: October 2022

Over half of global food waste occurs in retail and households, highlighting the importance of improving shelf life. Many factors affect shelf life, including storage temperature, harvest time, processing method, and packaging. Modified atmosphere packaging (MAP), such as nitrogen (N2), has been used to improve the shelf life of produce. This study aimed to determine the effect of nitrogen-enriched packaging on the shelf life of greenhouse- and garden-grown kale in raised beds outdoors. Five kale cultivars (Black Magic, Darkibor, Lacinato, Red Russian, and Westlander) were grown in the greenhouse, and four cultivars (Curly Roja, Dwarf Green Curled, Meadowlark, and Vates) outdoors in raised beds, harvested and stored in nitrogen-enriched or nonenriched bags for 6 days. Leaf water content, water activity, color, visual score, and texture were measured for each replicate. Nitrogen-enriched packaging did not affect the kale shelf life. Garden-grown kale exhibited significantly lower water activity (0.979 vs. 0.999) and noticeably lower water content (88.6 vs. 90.6%) than greenhouse-grown kale. The cultivars were significant for all factors tested except for texture on day 4 and change in light to dark (Δ L*) and blue to yellow (Δ b*) color ratios. At the end of the study, cultivars Darkibor and Curly Roja had the highest visual score (4.4) and texture (305 g), respectively. The high performance of ‘Darkibor’ and ‘Curly Roja’ in visual score and texture may be due to decreased (Δ L*) and (Δ b*) values and decreased water content and water activity values. Future breeding efforts focused on the shelf life of kale should use the top-performing cultivars identified in this study and a diverse genetic population tested in a range of environments to develop cultivars with a longer shelf life.
The Influence of Business Models, Information Technology on the Quality of Accounting Information Systems Digitizing MSMEs Post-COVID-19
Authors: Supriyati S , Mulyani Sri , Suharman Harry , Supriadi Taufiq
Published: October 2022

Many organizations realize the importance of building information systems based on the formulation of business models and implementing them into company activities. The survival of an organization is determined by its ability to compete in the market. In modern systems, there are dependencies between enterprise information systems, business models and enterprise business processes. There is an equally strong influence between business models and information systems. The goal achieved between business models and information systems is to maintain a balance between the three dimensions of sustainable development, namely: environmental, social, and economic. The research method used is qualitative with a field approach, an institutional approach, and a library approach. The types of data used in this research are primary data and secondary data. The data collection technique used is observation and literature study both nationally and internationally, while secondary data comes from journals, proceedings, government regulations, and statutory regulations. The output target achieved is obtaining business models, information technology on the quality of MSME accounting information systems after Covid-19.
An analysis on influencing factors of irrigation water effective utilization coefficient – A case study of Jiangsu province, China
Authors: Ju Yan , Xing Yang , Dong Azhong , Qi Fei , Hou Miao , Zhang Wenye
Published: October 2022

The irrigation water effective utilization coefficient (IWEUC) is a critical indication of agricultural water use efficiency. To improve water-saving potential, the inter-annual variation of IWEUC from 2014 to 2021 in Jiangsu Province was analyzed. Taking consideration of natural factors, planting structure, management levels, and water-saving engineering, the primary influencing factors of IWEUC were investigated through principal component analysis. The results revealed that IWEUC in Jiangsu Province was higher than the annual national level and showed an insignificant increasing trend. IWEUC and its trend were negatively correlated with irrigation district size. Water-saving irrigation areas had an extremely significant impact on IWEUC (P < 0.01). The positive load of water-saving engineering investment was rated first. Furthermore, economic and water-saving benefits for different irrigation district scales based on the TOPSIS model were evaluated. Despite restricted government support, the economic gains for large irrigation districts were superior to those for small irrigation districts. In the past decade, agricultural water declined while agricultural water conservation rose. The completion of integrated agricultural water pricing reform, as well as the improvement of water-saving engineering and optimization of management level, had a significant beneficial influence on IWEUC. Jiangsu's IWEUC has been efficiently implemented, and provides guidelines in other regions.
Interaction of TiO2 nanoparticles with the C. vulgaris: oxidative stress, lipid peroxidation and lipid amount
Authors: Sezer Mesut , Tanatti N. Pınar , Şengil İsmail Ayhan
Published: October 2022

Nanoparticles are widely used in many industries such as food and cosmetics. With increasing use, its spread to environmental environments is also increasing. Microalgae have an important place in the uptake of nanoparticles into the food chain. In this study, the effect of TiO2 nanoparticle on antioxidant enzyme activity, malondialdehyde, hydrogen peroxide, chlorophyll-a and total lipid amount in C. vulgaris microalgae has been investigated. As a result of the dose study, while the superoxide dismutase and ascorbate peroxidase enzyme activities decreased, the amount of MDA, H2O2 and chlorophyll-a increased. Depending on the times at different light:dark ratios, both an increase and a decrease occurred in the SOD, APX enzyme activity and the amount of MDA, H2O2. There was an increase in the amount of chlorophyll-a. In the time study, while the SOD and APX enzyme activities increased, the amount of MDA and H2O2 decreased. The amount of chlorophyll-a increased. In the total lipid study, the total lipid amount in the group with nano TiO2 increased compared to the control group. At the same time, C18:2 T (linoleic acid) has been found as fatty acid methyl ester in both groups.
The highly efficient simultaneous removal of Pb2+ and methylene blue induced by the release of endogenous active sites of montmorillonite
Authors: Luan Jingde , Zhao Chen , Zhai Qian , Liu Wengang , Ke Xin , Liu Xiaoyang
Published: October 2022

The inherent periodic structure of montmorillonite limits the adsorption capacity of its endogenous active units such as Si-O tetrahedron and Al-O octahedron for pollutants. The high-intensity ultrasound method was used to release these active units and the layer-by-layer assembly was adopted to prepare carbon@chitosan@montmorillointe microsphere adsorbent (C@CS@Mt) to give full play to the adsorption capacity of montmorillonite. The montmorillonite nanosheet exhibited good hole-making ability, resulting in high surface area, pore volume and pore diameter of microspheres. Benefitting from the release of active sites in Si-O tetrahedron and Al-O octahedron of montmorillonite nanosheets, the adsorption capacity of C@CS@Mt was significantly improved. The maximum adsorption capacities of Pb2+ and methylene blue (MB) reached 884.19 mg·g−1 and 326.21 mg·g−1, respectively. The simultaneous adsorption experiments indicated that the occupation of active sites by Pb2+ caused the observed decrease of MB adsorption capacity. The theoretical calculations indicated that Pb was preferentially adsorbed by active adsorption units due to strong electron donating ability in comparison to MB. As an active unit, Si-O tetrahedron exhibited stronger adsorption capacity for cationic dyes than Al-O octahedron due to both the large electronegativity and lower adsorption binding energy.
Fouling reduction in nanofiltration membranes in the treatment of municipal sewage – effect of coagulant type used for prior chemically enhanced primary treatment
Authors: Fida Sadia , Haydar Sajjad , Zeeshan Muhammad
Published: October 2022

The limiting factor in wide-scale application of membranes for wastewater treatment is membrane fouling. Coagulation has emerged as an effective technique for fouling control. In this research, municipal wastewater was treated using a two-stage treatment. In stage-1, chemically enhanced primary treatment (CEPT) was rendered using an optimum dose of two coagulants, i.e. alum, ferric chloride and a 1:1 mix of both. The optimum doses for coagulants were determined using a jar test. In stage-2, a nanofiltration (NF) membrane was used to further treat the effluent from stage-1. In CEPT, the 1:1 mixture of coagulants showed maximum removals, i.e. 75–77% for the total suspended solids and 73–75% for the chemical oxygen demand (COD). Stage-2 provided 85–95% removals for turbidity (0.88 nephelometric turbidity units), COD (41 mg/L), total dissolved solids (101 mg/L), hardness (11 mg/L as CaCO3), chlorides (80 mg/L), and heavy metals (copper [0.03 mg/L] and lead [0.02 mg/L]). The operational time of the NF membrane was 46 min, 55 min and 70 min using alum, ferric chloride, and mix (1:1), respectively. Significant reduction was observed in membrane fouling for 1:1 mixture of coagulants. The effluent met the US Environmental Protection Agency guidelines for non-potable reuse.
Lifestyle and Dietary Patterns as Risk Factors for Osteoporosis:
A Literature Review
Authors: Tayyem Reema , Abuhijleh Haya , Al-Khammash Amal
Published: October 2022

Background:

Osteoporosis is a major public health concern and is highly prevalent
worldwide. There is increasing evidence about the importance of nutrition to this chronic condition.

Aim:

In this literature review, we aim to show the association between dietary patterns and the
risk of developing osteoporosis.

Methods:

We reviewed and reported over 90 research papers published in Google scholar and
ScienceDirect between 1981 and 2020 that investigated a connection between nutrient intake, dietary
patterns and lifestyle and the risk of developing osteoporosis.

Conclusion:

Bone health is usually supported by nutrients such as calcium, phosphorus, potassium,
magnesium, vitamin K and vitamin D. Healthy dietary patterns with high intakes of fruits
and vegetables showed protective effects against osteoporosis. Physical activity and exercise also
showed beneficial effects in protecting BMD. Other factors such as smoking, alcohol consumption,
pregnancy and lactation, and body mass index are all associated with osteoporosis risk. On
the other hand, existing research shows that western dietary patterns ,including processed high
protein diets, sugar, candy, soft drinks, pizza, French fries, and refined grains, are associated with
low bone mineral density (BMD) and a high risk of fractures. Besides all that, it has been reported
that postmenopausal women tend to be primarily prone to osteoporosis, and this is mainly due
to hormonal insufficiencies.
Therapeutic Potential of Stable Organosulfur Compounds of Aged Garlic
Authors: Rani Vibha , Sharma Kumkum
Published: October 2022

Aged garlic extract (AGE) is an odorless derivative of garlic prepared by extracting garlic cloves in an aqueous solution for twenty months. During the process of aging, reactive organosulfur compounds such as allicin present in garlic are converted to their stable isoforms such as S- Allyl cysteine. The unstable organo sulfurs in garlic (Allium sativum L.) have been reported to cause problems in the gastrointestinal (GI) tract with an extremely pungent odor to attain its therapeutic potential. But these pharmacologically safer sulfur compounds of AGE have been studied and reported to have exceptional therapeutic potential in human health and various diseases. SAllyl cysteine (SAC), Diallyl disulfide (DADS), Diallyl trisulfide (DATS), S-allyl-mercaptocysteine (SAMC), are the most studied organosulfur compounds in in-vitro as well as in-vivo research. Biomedical research suggests that these phytoconstituents exhibit antioxidant, cardioprotective, cancer preventive, neuroprotective, immunomodulatory, antilipidemic, antidiabetic, hepatoprotective, and antiobesity effects. The therapeutic potential of aged garlic extract has been found to be extensively beneficial in these conditions, and provide a vast future in biomedical chemistry, herbdrug synergy and drug designing. The purpose of this review is to provide a mechanistic understanding of various organosulfur compounds of AGE in human health and disease based on data provided in the literature.
Formulation, Optimization and Characterization of Bupropion Hydrochloride
Loaded Nanostructured Lipid Carriers for Intra-Nasal Administration:
An Approach to Management of Smoking Cessation
Authors: Natarajan Jawahar , Rekharani Aravind Shyamprasad , Nidamanuri Bala Sai Soujith , Rajendra Praharsh Kumar Mandadhi , Venkatachalam Senthil , Selvaraj Jubie
Published: October 2022

Background:

Tobacco smoking is a major factor leading to cardiovascular diseases. About 48% of cardiovascular diseases occur due to cigarette smoking. Bupropion hydrochloride is a non-nicotine treatment for smoking cessation. The existing marketed formulation of bupropion has limitations, like low bioavailability and extensive first-pass metabolism. In order to boost the bioa-vailability and increase the brain biodistribution of the drug, a colloidal drug delivery system, like nanostructured lipid carriers, is employed.

Methods:

NLC formulation was prepared using the microemulsion technique and an optimized formula was developed using a three-level factorial design.

Results:

The particle size of the optimized formulation was 162 nm, the polydispersity index was 12.2%, and the zeta potential was -29.0mV. Entrapment efficiency was found to be 41.2%. SEM images show that these NLCs are spherical. In vitro drug release study was conducted, and at the end of 72 hours, 50% of the drug was released, indicating the sustained release of the drug. Histo-pathological studies were conducted using goat nasal mucosa, and results indicated the NLC formu-lation as non-toxic for intranasal administration.

Conclusion:

Thus, through the intra-nasal route, an increased concentration of drug can be deliv-ered to the brain via the olfactory pathway, thereby improving the therapeutic effect and exhibiting better patient compliance in smoking cessation.
Telemedicine using Machine Learning: A Boon
Authors: Yadav Seema , Bhole Girish P. , Sharma Avinash
Published: October 2022

Telemedicine is a part of e-Health that employs information communication
technologies (ICT) to transmit healthcare information required for educational and
therapeutic purposes. Telehealth attempts to overcome the challenges in the delivery of
health services due to distance, time, and challenging landscapes. It plays a significant
role during floods and earthquakes. It enables better access and cost-effectiveness in
both developing and developed world locations. The health sector has been
dramatically influenced and affected by the Covid-19 pandemic with the adoption of
improved technology that has allowed many people to access healthcare from the
comfort of their homes. Remote follow-up and monitoring are also provided through
Telemedicine as postoperative care. The possible scope and application of Artificial
Intelligence techniques in the Telehealth area are discussed in this paper. The paper
also focuses on different computational solutions involving machine learning and
Artificial Intelligence to tackle the crisis. The methods focus on two major areas: 1)
improvement in the quality of existing clinical practices, and service delivery. 2) the
growth besides the support of innovative models for healthcare. The methods to
improve quality include digital storage of patient data and large datasets, automation of
manual tasks for CT scans, conducting X-rays and handling the emergency, and
electronic consultation for diagnosis, treatment, and monitoring of patients. Innovative
methods such as ICT and technology such as accelerometers, GPS, gyroscopes, motion
sensors, and so on, are used in healthcare.
Sam Ratulangi's philosophical cultural ideas and their implications in the principle of just and civilized humanity
Authors: Pangalila Theodorus , Loho Ambrosius Markus , Tanase Tasente
Published: October 2022

The article aims to explore the philosophical thinking of Si Tou Timou Tumou Tou (living human to humanize others) concerning the noble values contained in the second principle of the Pancasila, "Just and Civilized Humanity." The background of this paper is the development of the current era that erodes human existence from social man to individualist man. This article is library research by exploring the thoughts of Sam Ratulangi through relevant books and sources and looking for their relevance to the precept of Just and Civilized  Humanity. The Si Tou Timou Tumou Tou is the most prominent Minahasan culture and animates the lives of the people of North Sulawesi in general and the people of the Tomohon city in particular. The values in the local wisdom of "Si Tou Timou Tumou Tou" are closely related to the fundamental values found in the second principle of Pancasila. The local wisdom of "Si Tou Timou Tumou Tou" and the second precept of Pancasila place human nature at an essential level in life.
“It really needs to be given to students” digital citizenship understanding amongst student teachers qualitative Nvivo analysis
Authors: Prasetiyo Wibowo Heru , Naidu Noor Banu Mahadir , Tan Bee Piang , Sumardjoko Bambang
Published: October 2022

Although the internet provides benefits, teachers’ role as central figures in the learning process is imperative. Due to misuse and abuse of technology, promoting digital citizenship for student teachers was challenging. Using nine elements of digital citizenship by Mike Ribble, this study explores the knowledge and comprehension of digital citizenship (DC) among twenty student teachers involved in semi-structured interviews, observation, and documentation. The result of thematic analysis with Nvivo 12 Plus indicates that student teachers assume that DC incorporates digital literacy, the standard of behaviors, and moral guidance in an online environment. The study contributes to providing insight regarding appropriate behavior in technology use. Further studies may need to be conducted regarding teacher preparation in managing the integration of digital citizenship into the teacher education.
THE IMPACT OF INTERNET ON TOURISM DEMAND
Authors: Bratić Marija , Petrović Jelena , Golubović Ninoslav , Anđelković Željko
Published: October 2022

In the XXI century, one of the trends in tourism as a leading service sector is Internet usage. The aim of this paper is to examine whether the use of the Internet (by companies and individuals) has a different impact on domestic and inbound tourism demand in the European Union for the 2010-2019 period. The results of the research indicate that the Internet usage by companies has an important positive impact on the domestic and inbound tourism expenditure in developed and transition countries in European Union while the Internet usage by individuals has an important negative impact only on the domestic tourism expenditure in transition countries in European Union. At the same time, results show that Internet usage by companies has a higher impact on domestic tourism expenditure than on inbound tourism expenditure in developed and transition countries.
On the coordinate systems transformation
Authors: Neiman Yu.M. , Sugaipova L.S.
Published: October 2022

Determination of coordinate systems’ parameters transformation has always been and remains the core of surveyors’ practical and theoretical works. However, in most cases, the issue is interpreted under the assumption that the angular rotation of the coordinate axes and the similarity parameter are very small, which enables a significant simplifying of the algorithm. In this paper the strict theory of determining the 7 and 9 parameters of coordinate systems transformation within the framework of nonlinear method of least squares with limitations is considered. Strict algorithm is described and numerical experiments are performed. The connection of the coordinate systems transformation theory with the general one of mathematical statistics, known under the name of Procrust analysis, is specified. However, in general, artificial neural network theory is recommended for conversion of one coordinate system to another. This generally eliminates the need for a prior determination of the transformation’s appropriate parameters, inevitably associated with hypotheses for the transformation model, but quickly and accurately solves the main problem.
Efficacy of the U.S. Navy Treatment Tables in treating DCS in 103 recreational scuba divers
Authors:   UCLA Radiation Oncology, Los Angeles, California U.S., Chin Walter , Joo Ellie , Ninokawa Scott , Popa Daniel A. , Covington Derek B
Published: October 2022

Despite the fact that current decompression schedules reduce the risk of decompression sickness (DCS), recreational scuba divers continue to experience DCS. Therapy outcomes in these divers are difficult to track. Our study aims to understand the efficacy of the United States Navy (USN) Treatment Tables (5, 6, 6A, 9) in providing symptomatic relief among recreational scuba divers. We conducted a single-center retrospective review of recreational divers treated from 2003 to 2013. A total of 187 divers were identified: 84 divers were excluded, and the charts of the remaining 103 divers were independently reviewed by three clinicians. For these 103 divers, the response variable, therapy outcome, was categorized as no relief, partial relief, or complete relief of symptoms. In a population of 76 males and 27 females with an average of three dives and three treatments, 53 patients achieved complete symptomatic relief, 45 patients had partial relief, and five patients reported no relief at the end of all recompression treatments. Among the patients who achieved complete symptomatic relief, 28 (53%) needed only one recompression treatment. The depth of the diver’s first dive and the change in symptoms within the first 20 minutes of the first recompression treatment were found to be explanatory variables of the treatment outcome.
Modifying Kurchatov's method to find multiple roots of nonlinear equations
Authors: Torregrosa Juan Ramon , Cordero Alicia , Garrido Neus , Triguero-Navarro Paula
Published: October 2022

In this work, we modify the iterative Kurchatov’s method to solve
nonlinear equations with multiple roots, that is,for approximating the
solutions of multiplicity grater than one. Its main feature is that you
do not need to know a priori the multiplicity of the root, which does
not appear in the iterative expression. We perform a dynamical analysis
to see the behaviour of the proposed method. We also carry out some
numerical experiments to confirm the theoretical results and compare the
proposed method with other known schemes for multiple roots.
PEMBELAJARAN BANGUN DATAR MENGGUNAKAN PERMAINAN ANAK TRADISIONAL INDONESIA
Authors: Muslihatun Ana , Sugiman Sugiman
Published: October 2022

Kegiatan pembelajaran bangun datar yang hanya menitikberatkan pada prosedur formal, tidak mampu mengembangkan lintasan belajar siswa. Oleh karena itu, pembelajaran bangun datar menggunakan konteks permainan tradisional menjadi salah satu alternatif yang dapat dilakukan. Tujuan penelitian ini adalah untuk mendeskripsikan learning trajectory siswa dalam mengkonstruksikan konsep luas bangun datar dengan menggunakan konteks bentuk papan permainan dam-daman sebagai titik awal pembelajaran. Metode penelitian ini menggunakan penelitian kualitatif berupa design research. Hasil dari penelitian ini adalah serangkaian aktivitas pada tingkat situational, referensial, general, dan formal. Pada tingkat situational, pemahaman awal secara langsung bentuk-bentuk bangun datar menggunakan bentuk papan permainan dam-daman. Tingkat referensial, siswa  merepresentasi bentuk bangun apa yang ditemukan pada papan permainan dam-daman melalui representasi gambar.  Tingkat general, siswa menghitung luas dari suatu bangun dengan menggunakan satu satuan luas yang telah ditentukan. Terakhir, tingkat formal, siswa merekonstruksi pemahaman mereka untuk menentukan rumus masing-masing luas bangun datar. Simpulan dari penelitian ini menunjukkan bahwa papan permainan dam-daman mampu merangsang siswa dalam mengkonstruksikan konsep luas bangun datar seperti persegi panjang, segitiga, jajar genjang, dan trapesium.
LKPD BERBASIS MIND MAPPING: UPAYA MENDUKUNG PENINGKATAN PENALARAN MATEMATIS PADA MATERI EKSPONEN DAN LOGARITMA
Authors: Fitrianingrum Melinia Astri , Sari Christina Kartika
Published: October 2022

The lack of teaching materials that support the exponential and logarithmic learning process to improve students' mathematical reasoning abilities causes this ability to be not optimal. The purpose of research and development was to develop student worksheets based on mind mapping that was valid and feasible in supporting the improvement of mathematical reasoning on exponential and logarithmic material. The research used the ADDIE development (Analysis, Design, Development, Implementation, Evaluation). This article describes only the development stage. First, the analysis phase is carried out through curriculum analysis, student characteristics, and material analysis. In contrast, the design phase is carried out with the preparation of product manufacture, the basic framework related to material, and the trial of product instruments. Next, the development stage consists of making LKPD products based on mind mapping, validation of worksheets, practicality tests, and feasibility tests of worksheets. The research subjects in the analysis stage are mathematics teachers and students, while the researcher is in the design stage. In contrast, the development stage is three experts as validators, user teachers as practitioners, and six students of SMA Negeri 1 Kembang class X in the 2021/2022 academic year. The research data were obtained through observation, documentation, interviews, and questionnaires. The study results indicate that the mind mapping-based LKPD development design has a good category. After being declared valid, the practicality test was carried out on the user teacher and claimed practical with an average score of 4.00. After being declared applicable, the feasibility test was carried out to students by distributing questionnaires and was declared very suitable for use with an average score of 4.05.
ELEMENTARY SCHOOL STUDENTS' ERRORS IN SOLVING WORD PROBLEMS BASED ON NEWMAN ERROR ANALYSIS
Authors: Prasetyaningrum Hesty Dian , Amir Mohammad Faizal , Wardana Mahardika Darmawan Kusuma
Published: October 2022

Based on previous studies, elementary school students often experience errors in solving word problems on cube and block material. Confirmed Newman Error Analysis (NEA) can analyze the location of student errors in solving word problems. Hence, the purpose of this study was to analyze the errors made by students in solving word problems based on NEA. The type of research used is qualitative research with case studies. The research subjects were 34 students of grade five elementary students with data collection techniques, including tests, interview sheets, and documentation. Data analysis using NEA consists of five stages: reading, comprehension, transformation, process skills, and encoding. From the study results, reading errors were 12,74%, comprehension errors were 51,96%, transformation errors were 9,8%, process skills errors were 52,94%, and encoding errors were 67,64% of students. These errors are caused because students do not read and understand the questions, do not know the formulas and arithmetic operations model used, and count errors.
STRATEGI KORPS PASUKAN KHAS TENTARA NASIONAL INDONESIA ANGKATAN UDARA DALAM OPERASI PENANGGULANGAN BENCANA ALAM (Studi Kasus Penanggulangan Bencana Alam Gempa Bumi dan Tsunami di Kepulauan Mentawai Tahun 2010)
Authors: Risdar Frian Alfa , Djuyandi Yusa , Hidayat Taufik
Published: October 2022

Penelitian ini bertujuan untuk mendeskripsikan dan menganalisis strategi Korpaskhas TNI AU dalam operasi dukungan penanggulangan bencana alam gempa bumi dan tsunami di Kepulauan Mentawai tahun 2010. Metode yang digunakan dalam penelitian ini adalah metode kualitatif dengan pendekatan studi kasus. Teknik analisis data yang digunakan adalah teknik analisis data interaktif Miles dan Huberman yang terdiri dari reduksi data, penyajian data, dan diakhiri dengan penarikan kesimpulan/verifikasi. Teknik pengumpulan data dilakukan dengan wawancara mendalam, observasi, studi kepustakaan dan studi dokumen. Hasil penelitian menunjukkan bahwa strategi Korpaskhas TNI AU dalam operasi dukungan penanggulangan bencana alam gempa bumi dan tsunami di Kepulauan Mentawai tahun 2010 yaitu melakukan persiapan personel dan perlengkapan secara cepat dan cermat, membagi pasukan kerja ke dalam unit-unit kecil yang memiliki tugas-tugas tersendiri untuk mencapai tujuan yang telah ditetapkan, melaksanakan tugas penanggulangan berdasarkan permintaan atau perintah dari institusi yang lebih tinggi, menggerakkan pasukannya dengan menggunakan perlengkapan khusus, menggunakan taktik tertentu dalam memasuki wilayah terjadinya bencana, dan selalu melaksanakan koordinasi dengan satuan lain pada saat di lapangan.
OVERCOMING TERRORISM THREATS IN AIR FORCE BASE : CASE STUDY OF HALIM PERDANAKUSUMA AIR FORCE BASE
Authors: Pramono Sony Aji , Sudirman Arfin , Djuyandi Yusa
Published: October 2022

ABSTRACT: Terrorism is one form of transnational crime and is very threatening tranquility and peace. In Indonesia, terrorism crimes often occur and consume victims that are not small in number from their own citizens or from foreign nationals. The purpose of the study "Overcoming Terrorism Threats at Air Base: Study of terrorism threat prevention cases at Halim Perdanakusuma Air Base" is to describe and analyze the handling of terrorism threats at the Base Air both in terms of policy and technical. The indicators used in this study are the ability of the Air Base and Halim Perdanakusuma Airport to be viewed from aspects of human resources, infrastructure, operations, supervision and equipment. The informants in this study were Air Base personnel, Angkasa Pura and officials in the Halim Perdanakusuma Air Base area. The research data is preceded by collecting secondary data and then followed by interviews and observation methods. Based on the results of the research carried out, it was obtained the results that counterterrorism at Halim Perdanakusuma Air Base was seen from the aspect of human resources, infrastructure, operations, supervision and equipment was still not optimal. So it needs a method that is solved in an innovative idea where it will indirectly provide input in improving terrorism threat control at Halim Perdanakusuma Air Base and Halim Perdanakusuma Airport.
Efektivitas Program Layanan Transjakarta Cares Bagi Penyandang Disabilitas di DKI Jakarta
Authors: Akbar Alfredo , Miradhia Darto , Buchari Rd Ahmad
Published: October 2022

This study was conducted to identify the effectiveness of the Transjakarta Cares service program for persons with disabilities in DKI Jakarta to be able to determine the extent to which the Transjakarta Cares service program is able to provide the needs according to the wishes of persons with disabilities. In this study, the author uses the theory issued by Edy Sutrisno which measures the effectiveness of the program with five aspects, namely understanding the program, being on target, being on time, achieving goals, and real change. Then the researchers in this study used qualitative methods to be able to explain in detail the effectiveness of the Transjakarta Cares service program. According the results of the research that researchers have done, it can be seen that the Transjakarta Cares service program for persons with disabilities in DKI Jakarta has not been effective. This is reviewed through five aspects that are considered to have not been able to be fulfilled to the maximum. From the aspect of understanding the program, it can be assessed that not all parties have a good understanding of the Transjakarta Cares program, the timely aspect that has not been carried out according to the procedure, and the aspect of achieving the goals that have not been achieved. Because of this, the Transjakarta Cares service program is considered ineffective and requires program evaluation to be able to improve the service program provided to persons with disabilities. Penelitian ini dilakukan untuk mengidentifikasi terkait dengan efektivitas dari program layanan Transjakarta Cares bagi penyandang disabilitas di DKI Jakarta untuk dapat mengetahui sejauh mana program layanan Transjakarta Cares mampu memberikan kebutuhan yang sesuai dengan keinginan dari penyandang disabilitas. Dalam penelitian ini penulis menggunakan teori yang dikeluarkan oleh Edy Sutrisno yang mengukur efektivitas program dengan lima aspek yaitu pemahaman program, tepat sasaran, tepat waktu, tercapainya tujuan, dan perubahan nyata. Kemudian peneliti dalam penelitian ini menggunakan metode kualitatif untuk dapat menjelaskan secara rinci terkait efektivitas dari program layanan Transjakarta Cares. Berdasarkan hasil penelitian yang telah peneliti lakukan dapat diketahui bahwasanya program layanan Transjakarta Cares bagi penyandang disabilitas di DKI Jakarta belum efektif. Hal ini ditinjau melalui lima aspek yang dinilai belum mampu terpenuhi dengan maksimal. Dari aspek pemahaman program yang dapat dinilai belum semua pihak memhami dengan baik program Transjakarta Cares, aspek tepat waktu yang belum sesuai prosedur, serta aspek tercapainya tujuan yang belum tercapai. Oleh karena ini hal ini membuat program layanan Transjakarta Cares dinilai belum efektif dan membutuhkan evaluasi program untuk dapat meningkatkan program layanan yang diberikan kepada penyandang disabilitas.