bluuebunny/crossref_metadata_2025 huggingface dataset:
Nghiên cứu lựa chọn chế phẩm sinh học tạo Floc phù hợp trong nuôi tôm thẻ chân trắng
Authors: Huỳnh Kim Khánh , Phương Minh Nam , Võ Văn Nha , Võ Thị Ngọc Trâm , Huỳnh Minh Sang Minh Sang
Published: December 2023

Lựa chọn chế phẩm sinh học tạo floc phù hợp cho nuôi tôm thẻ chân trắng (Litopenaeus vannamei) nhằm mục đích đạt được hiệu quả tối ưu nhất về sử dụng thức ăn, nâng cao chất lượng cải thiện môi trường mà vẫn đạt năng suất tôm cao. Bốn loại chế phẩm (NT1, NT2, NT3 và NT4) được sử dụng để nuôi tôm thẻ chân trắng và đánh giá các chỉ tiêu bao gồm vi khuẩn Vibrio spp. và Bacillus spp. trong môi trường nuôi, mật độ hạt floc; tỷ lệ sống (%), khối lượng (g) và hệ số chuyển đổi thức ăn (FCR) của tôm sau 1 tháng nuôi. Kết quả nghiên cứu sau 4 tuần nuôi cho thấy mật độ Vibrio spp. và Bacillus spp. cao nhất ở nghiệm thức NT1 (p< 0,05), còn nghiệm thức NT4 cho kết quả mật độ Vibrio. spp thấp nhất (p < 0,05). Mật độ Bacillus spp. ở các nghiệm thức NT2, NT3 và NT4 không có sự khác nhau sau 4 tuần nuôi (p > 0,05). Kết quả kiểm tra mật độ floc ở nghiệm thức NT1 cao nhất (p < 0,05) và không phát hiện được ở nghiệm thức NT4. Hệ số chuyển đổi thức ăn (FCR) và tỷ lệ sống của tôm ở các nghiệm thức không có sự khác biệt về mặt thống kê. Khối lượng tôm thấp nhất ở NT2. Kết quả nghiên cứu cho thấy chế phẩm sinh học tạo floc NT1 là chế phẩm có hiệu quả nhất trong các loại chế phẩm được sử dụng khi nuôi tôm thẻ chân trắng.

Từ khóa:  Floc, chế phẩm sinh học, tôm thẻ chân trắng.
Phương pháp thu hoạch vi tảo và ứng dụng trong nuôi trồng thủy sản
Authors: Phạm Thị Đan Phượng
Published: December 2023

Vi tảo là sinh vật đơn bào có cấu trúc đơn giản khả năng thích ứng và sinh trưởng mạnh trong nhiều điều kiện môi trường trường sống. Vi tảo giữ vai trò quan trọng trong nhiều hệ sinh thái các thủy vực, nhiều ngành kinh tế, và nguồn thức ăn cần thiết, không thay thế đối với ấu trùng động vật thủy sản. Vi tảo được xem là nguồn thức ăn giàu dinh dưỡng gồm proteins, lipids, carbohydrates, khoáng chất, vitamins, chlorophylls, carotenoids. Đến nay, đã có nhiều phương pháp thu vi tảo được nghiên cứu và thực hiện trong các ngành công nghiệp như sản xuất nhiên liệu sinh học, thực phẩm, dược phẩm, mỹ phẩm và nuôi trồng thủy sản. Tuy nhiên, trên thực tế quá trình loại nước trong thu hoạch vi tảo vẫn đang đối diện với nhiều thách thức, nhất là chi phí đầu tư lớn, tiêu tốn năng lượng, và nhân công. Bài viết này đề cập đến ưu nhược điểm của một số phương pháp thu vi tảo chính và phân tích tiềm năng áp dụng phương pháp thu vi tảo bằng polyme sinh học. Phương pháp này đảm bảo an toàn cho động vật khi sử dụng vi tảo làm thức ăn, có vai trò quan trọng đối với phát triển bền vững ngành nuôi trồng thủy sản. Khi có sự kết hợp với các phương pháp thu hoạch khác, hiệu quả thu hoạch sẽ cao, tiết kiệm năng lượng đáng kể, dễ vận hành và phát triển công nghệ thu hoạch vi tảo ở quy mô công nghiệp.

Từ khóa: Nuôi trồng thủy sản, chitosan, phương pháp thu hoạch, vi tảo
Adsorpsi Logam (Pb) dengan Menggunakan Biji Kelor sebagai Adsorben
Authors: Sharah Muh. Agus
Published: December 2023

Lead or in everyday life is better known as lead, in scientific language it is called lead, and this metal is symbolized by Pb. This metal is included in group IV-A metals on the periodic table of chemical elements. It has an atomic number (NA) of 82 and an atomic weight (BA) of 207.2 (Palar, 2008). Lead in air is in the form of Pb (OH)2. Most of the lead metal on earth enters natural water systems and accumulates, which can eventually enter the bodies of animals and humans, which can cause children's intelligence to decrease, stunted body growth, and even cause paralysis. other symptoms such as poisoning, nausea, anemia, and stomach ache. One absorbent material that can be used to adsorb heavy metals such as lead is moringa oleifera seeds. This research uses a method to obtain the desired quantitative and qualitative data regarding PB metal content before adsorption and after adsorption, adsorption time, and quality of Moringa seeds as an adsorbent, then analyzed proximally. The results of the research showed that the Pb concentration in Tallo River water was 0.0204 mg/L, but after adding Moringa seed adsorbent, the Pb concentration dropped to <0.002mg/L, this means that Moringa seeds are very good at absorbing Pb metal. Hulled Moringa seeds tend to absorb more easily than whole Moringa seeds. The longer the adsorbent takes to adsorb, the Pb concentration decreases until the Pb concentration remains relatively constant.Keywords: Adsorption; Absorbent, Moringa Seeds,Metal
Etnobotani Keragaman Tumbuhan Pangan dan Pemanfatannya di Desa Labulia Kecamatan Jonggat Lombok Tengah
Authors: Amrullah Lalu , Gaffar Affan , Marsahip Marsahip
Published: December 2023

Food is the main human need and continues to increase along with population growth. Food needs can be met from existing natural resources, especially from plants. Ethnobotany is a science that studies interactions between humans and plants, one of which is to meet food needs. The pattern of plant use by a society is closely related to their culture. So the culture of a region can determine the type of food, how it is processed and served. The use of plants is something that is inherent in the Using tribe, especially in meeting food needs. This research aims to gain knowledge about the diversity of types of food plants used by the community in Labulia Village, Jonggat District. The respondents used in this research were 28 people who were people who lived in the area. Data collection was carried out using interviews, questionnaires, random sampling and observation of food plant information including types, benefits and parts of plants used. Food plants used by the people of Labulia Village, 71 species consisting of 41 families. The research results show that the most widely used part of the plant is fruit with a percentage of 83%. This plant is used for foodKeywords: Ethnobotany, Food plant diversity, Labulia Village
Analisis Stabilitas Lereng dengan Metode Bishop pada Proyek Geotechnical Investigation Jalur Transportasi Pelabuhan Batubara Marangkayu Kabupaten Kutai Kartanegara
Authors: Rumbyarso Yonas Prima Arga , Pribadi Gali
Published: December 2023

A slope is a surface that has a slope and forms a certain angle to the horizontal plane and is not protected. The slope and angle formed cause the slopes to have differences in surface height. Differences in slope surface height result in forces acting to push, and also forces in the soil acting to resist or resist, so that the position of the soil remains stable. The stability of a slope is expressed in the slope safety factor which is obtained or obtained by comparing the holding force and the pushing force. Based on topographic data of ground investigation drilling points on the Marangkayu Coal Port transportation route, Kutai Kartanegara Regency, it is known that there are several drilling points with soil conditions in the form of slopes or hills, so it is predicted that they could cause the potential for landslides because these points will become transportation routes for loading and unloading materials. coal. The aim of this research is to determine the slope safety figures, and to obtain a safe slope with the original slope conditions. The method used to analyze slope stability in this research uses Geostudio Slope Bishop method software. The results of the analysis of the original slope conditions at the OLC-FBH-03 and OLC-FBH-06 test points showed that the slope safety value was obtained with the result being that the slope condition was safe from landslides (FK>1.25). With this, it can be concluded that the Marangkayu Coal Harbor transportation route, Kutai Kartanegara Regency is safe from landslides.Keywords: Bishop Method, Geostudio Slope, Slope Stability, Slope Safety Value
Pengembangan Sistem Informasi Administrasi Kependudukan Desa Gumelem Wetan Berbasis Website
Authors: Muflih Ghufron Zaida , Ardiansah Rifki
Published: December 2023

Gumelem Wetan Village is a village in Susukan District, Banjarnegara Regency which is located ± 36 Km from the city center. In the implementation of population administration in Gumelem Wetan Village for population data processing from recording, making certificates to reporting population data, births, deaths, and moves is still manual bookkeeping. This of course reduces the effectiveness and efficiency of population data management. Technology, information and communication have developed very rapidly, this must be used to facilitate the management of population data in Gumelem Wetan Village because technology can provide convenience for humans in various aspects of life. In Indonesia, almost all companies and institutions, both government and private, have sophisticated data processing technology, so the presence of information technology is very necessary. Unlike the data processing in Gumelem Wetan Village which is still bookkeeping, a website-based population administration information system is needed for Gumelem Wetan Village that is able to manage population data effectively and efficiently. So that it can facilitate the performance of the Gumelem Wetan Village Government apparatus. In addition, it can also improve public services, especially administrative services for the people of Gumelem Wetan Village. This study used interviews, literature review, and observation as data collection methods. While the system development method uses the waterfall method using the PHP (Hypertext Preprocessor) programming language. The output of this research is a website-based population administration information system in Gumelem Wetan Village.
 Keywords: Population Administration Information System, Gumelem Wetan, Data Processing, PHP, Waterfall Method
Analisis Ketersediaan dan Kebutuhan Air Serta Penentuan Pola Tanam pada Irigasi Air Palik Aur Gading Kabupaten Bengkulu Utara
Authors: Amri Khairul , Supriani Fepy , Darmo Serlinna Anggraini
Published: December 2023

Air Palik Irrigation Area is located in Aur Gading Village, North Bengkulu Regency with a potential area of 1015 Ha with a functional area of 950 Ha. Climate change in Indonesia affects rainfall intensity, temperature, air pressure, humidity and water availability. Limited water availability will hamper the growth process for plants. Based on this, this research was conducted to determine the comparison of water needs and availability in the Air Palik Aur Gading irrigation area and the determination of cropping patterns. The methods used in this study include the aljabar average method to analyze rainfall, the F.J. Mock method to determine the value of water availability and 2 methods, including KP-01 and the CROPWAT 8.0 to determine the value of water demand used. The results showed that the maximum mainstay discharge occurred in November period 2 of 7.11 m3/second. The maximum irrigation water requirement in the KP-01 method was obtained at 3.12 liters/second/hectare which occurred in the first period of August while in the CROPWAT 8.0 method it was obtained at 1.16 liters/second/hectare which occurred in the third period of May.
Keywords: Water Demand, Water Availability, Cropping Pattern, KP-01, Cropwat Software Version 8.0
Editorial - N.º 11 / 2-2023
Authors: Rita Annabela , Franco José Eduardo , Martuscelli Tania
Published: December 2023

The thematic dossier of this year-end edition pays homage to two geniuses of Surrealism, Mário-Henrique Leiria (1923-1980) and Mário Cesariny (1923-2006), who reached the milestone of 100 years in 2023. Both multifaceted artists dedicated themselves passionately to artistic and literary expression in the pursuit of freedom. In the multi-themed section, diversity reigns: from the artistic expression of epidemics to heritage and an essay on the expropriation process of master craftsmen in contemporary Portugal. The interview constitutes a dialogue with the renowned professors, researchers, and activists Catherine Walsh and Walter Mignolo, both indispensable figures in the field of decolonial studies. In the Critical Readings section, two works and a cinematographic diptych are discussed. And, as usual, the magazine looks to the future with the presentation of a project, the Global History of Economy and Management in Portugal.
Entrevista a Walter Mignolo e Catherine E. Walsh
Authors: Martuscelli Tania , Cantu-Guerra Jonatan , Berjano Rodríguez Daniel , Berjano Blanca
Published: December 2023

Catherine E. Walsh (1964) had her initial experiences as an activist at the University of Massachusetts (Amherst), influencing her academic interests in pedagogy, decoloniality, and feminism. After completing her Ph.D. in Education in 1984, she worked at the University of Massachusetts in Amherst and Boston until the mid-1990s when she permanently relocated to Ecuador. Among her many activist contributions, she stands out for her work alongside Paulo Freire and the critical pedagogy network in the 1990s, bilingual education and consulting projects for indigenous communities in Ecuador, and the establishment of the Fondo Documental Afro-Andino, jointly with Afro-Ecuadorian community leader and intellectual Juan García Salazar in 2002, with whom she co-authored To Think Sowing/To Sow Thinking with Grandfather Zenon (2017). Notable among her various works are the edited volumes Decolonial Pedagogies (2013), On Decoloniality (in collaboration with Walter Mignolo, 2018), and her latest work, Rising Up, Living Up. Re-Existances, Sowings, and Decolonial Cracks (2023, Duke University Press). She recently retired as a professor and director of the Ph.D. program in Latin American Cultural Studies at the Universidad Andina Simón Bolívar (Quito, Ecuador). Walter Mignolo (1941) specialized in Semiotics and Literary Theory and has made extensive contributions to the fields of modernity and coloniality. His work prominently explores the concepts of decoloniality, global colonialism, geopolitics of knowledge, border thinking, and pluriversality. He is a central figure in the Latin American decolonial thought school, with a profound impact on global academic discourse. The author of several books translated into other languages, notable among them, in addition to On Decoloniality, co-authored with Walsh, are The Darker Side of the Renaissance: Literacy, Territoriality, and Colonization (1996), winner of the Katherine Singer Kovaks Award, The Idea of Latin America (2006), winner of the Frantz Fanon Award, and his most recent work, The Politics of Decolonial Investigations (2021). He has been working at Duke University since 1993, where he holds the distinguished title of «William H. Wannamaker» as a professor of Literature and Romance Studies. The works developed by Walsh and Mignolo are an extension of the concept of coloniality initiated by the Peruvian sociologist Aníbal Quijano, whom they consider disciples.
«Os Surrealistas», no centenário de Mário Cesariny e de Mário-Henrique Leiria
Authors: Franco António Cândido
Published: December 2023

This article seeks to examine the roots of the organized surrealism in Portugal, in the second half of the 1940s, starting with the dialogue between two young poets, Mário Cesariny and Alexandre O’Neill, who were instrumental in the formation of the Surrealist Group of Lisbon (1947-1950). An attempt is made to understand the tensions that erupted within this group, leading to the resignation and departure of Mário Cesariny and António Domingues in the summer of 1948 and the subsequent formation of the group «The Surrealists» (1949-1952). This group emerged from encounters with a new set of personalities, including notable figures such as Cruzeiro Seixas, António Maria Lisboa, and Mário-Henrique Leiria, providing a renewed consistency to surrealist intervention in Portugal.
Performance Evaluation of Vapour Compression Cascade Refrigeration System for Storing Blood Plasma
Authors: Oginni Olarewaju Thomas
Published: December 2023

A cascade refrigeration system consists of two cycles to get the greatest possible refrigeration effect for applications requiring extremely low temperatures. The experimental examination of the cascade refrigeration system utilized for quickly freezing and storing blood products, notably plasma, was the main emphasis of this paper. This system is able to manage and apply cold storage for plasma at temperatures as low as -35oC. R410A (low temperature cycle) and R404A (high temperature cycle) are the working fluids in this system respectively, and their selection was based on their reasonable boiling point differences and rapid freezing times. These working fluids have very little ozone depletion and global warming potential, and they are non-toxic to the environment. This system performance evaluation determines the cascade refrigeration system's parameters ranging effects of variation in evaporator temperature, condenser temperature and temperature difference in cascade condenser. As the evaporator temperature increases from – 35oC to -70C at interval of 7oC, the suction pressure increased from 0.22 MPa to 0.64 MPa. The decrease in compressor discharge temperature of 30oC to 26oC resulted to decrease in discharge pressure ranging 1.62 to 1.49MPa in the high temperature cycle at constant condenser temperature of 40 0C. At varying heat exchanger temperature, all parameters reduced with exception of discharge temperature in both cycles and evaporator heat.   A substantial increase in the coefficient of performance of comparable systems was found to be 3.04 (LTC) and 7.7 (HTC). At the high temperature cycle condenser, there was a total heat rejection of 6228 kJ, which could then be recycled for heating.
Mesenchymal and mononuclear stem cell therapy for acute ischemic stroke - A systematic review
Authors: Mohammad Kurniawan  , Yetty Ramli  , Teguh A S Ranakusuma  , Salim Harris  , Al Rasyid  , Taufik Mesiano  , Rakhmad Hidayat
Published: December 2023

Background: Studies have shown that stem cells have promising effect in ischemic stroke management. As an alternative therapy, the effectiveness and safety of mesenchymal (MSC) and mononuclear (MNC) stem cells in acute stroke are still unclear. This review evaluated the efficacy and safety of the use of MSC and MNC in acute ischemic stroke in terms of clinical and structural improvement.
Methods: This is a systematic review which is conducted based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guideline. Our review focused on RCT, with acute ischemic stroke population using MSC or MNC, and evaluated the clinical and structural improvements, and safety outcome after administration of the stem-cells.
Results: Eight studies were included, consisted of 155 patients in intervention and 408 in control group. In the MNC group, there was significant improvement of NIHSS within one month and achieved mRS ≤ 1 by six months. Slightly different from MNC, studies using MSC showed mRS improvement occurred after 3 months and NIHSS-motor improvement achieved after 2 years of infusion. One month after cell infusion, MRI showed structural improvement, with infarct expansion ratio of 0.9 ± 0.2 (p < 0.05). There was no differences in adverse events between intervention and control group in all studies.
Conclusions: This review show that MSC and MNC stem-cells are effective and safe to use as alternative treatment in acute ischemic stroke if other definitive measures could not be done or not available.
Predictors associated with stroke after coronary artery bypass grafting in Turkish population
Authors: Eruyar Esra , Kaan Kaya
Published: December 2023

Background Objective: Postoperative stroke is a serious adverse event, a major cause of morbidity and mortality after coronary artery bypass grafting (CABG). This study is designed to determine the incidence of stroke after CABG and to identify the preoperative, intraoperative and postoperative risk factors associated with the development of a stroke.
Methods: Between January 2019 and December 2022, 1.555 CABG were performed. Retrospective analysis of the patient files revealed that 24 (1.48%) patients had stroke in the postoperative period. Variables were compared with patients without neurological deficits (n=50) who had undergone CABG. Predictors of preoperative, intraoperative and postoperative stroke were identified.
Results: The incidence of postoperative stroke was 1.48% (n=24). Mean age of these patients was 63.86 ± 8.58 years, and 59 (79.7%) were males. Chronic renal failure (p= 0.011), previous CABG (p=0.009), carotid artery disease (p=0.009), CRP levels (p=0.004) and Monocyte/Lymphocyte ratio (p=0.019) were identified as important preoperative risk factors for stroke development but there were no diffirence prevalence of age, sex, diabetes, hypertension, congestive heart failure and atrial fibrillation.
Conclusion: Five variables (chronic renal failure, prior CABD, prior carotid artery disease, preoperative CRP levels and Monocyte/Lymphocyte ratio were found as risk factors for stroke after CABG. The development of postoperative stroke is associated with multiple morbidities and increased mortality. Careful assessment and management of risk factors should be implemented to reduce this important complication after CABG.
A rare epilepsy phenotype in Gabriele-de Vries syndrome: A new case and literature review
Authors: Woo Hyewon , Kim Won Seop , Kim Jon Soo
Published: December 2023

Gabriele-de Vries syndrome (GADEVS) is an extremely rare genetic syndrome characterized by mild-to-profound intellectual disability/developmental delay and a wide spectrum of clinical features. Herein, we report a case involving a rare early childhood epilepsy phenotype in a patient diagnosed with GADEVS based on the typical clinical features and the identification of a pathologic variant of the Yin Yang 1 (YY1) gene. A 3-year-old girl with global developmental delay, failure to thrive, and facial dysmorphism was referred to our rare genetic clinic. She also presented with cognitive impairment, hypotonia, hyperlaxity, strabismus, and autistic features. Whole genome sequencing identified a de novo heterozygous missense variant in the YY1 (c.1130A>G; p.His377Arg) gene. Notably, she developed afebrile seizures with abnormal electroencephalogram in early childhood. Currently, she has been seizure-free for more than 2 years with valproic acid. This case expands the epilepsy phenotypic features of GADEVS and reviews the association between the loss-of-function of the YY1 gene and epileptogenesis and possible treatment options.
The level of physical activity among ambulant stroke survivors at one year: a cross sectional study in a tertiary center in Malaysia
Authors: Jilimin Mitchel Brian , Mazlan Mazlina
Published: December 2023

Background & Objective: Despite the importance of physical activity, there is lack of evidence measuring the level of activity performed by the stroke survivors. This study aims to determine the level of physical activity amongst ambulant stroke patients in a tertiary centre in Malaysia and to investigate the factors that may impact their physical activity.
Methods: A cross-sectional study was conducted on ambulant stroke participants at one year post stroke. International Physical Activity Questionnaire (IPAQ) was used to measure the level of physical activity, and 6 Minute Walk Test (6MWT) was recorded to assess the participants functional walking distance and endurance. The participants were categorised into low, moderate, or high physical activity levels. Age-matched healthy controls were recruited form community. Factors including presence of depression were tested in relation to physical activity. P-value of <0.05 was considered statically significant in all statistical analyses.
Results: There were 45 stroke patients and 30 controls recruited in this study. Participants in the stroke group has significantly lower level of physical activity compared to the control group, especially in the high physical activity level (p<0.001); 55.6% reported having moderate, 31.1% low and 13.3% high physical activity level respectively. No significant factors were found to be associated with the physical activity. Only depression was found to have a weak negative correlation with level of physical activity (p=0.003).
Conclusion: Stroke survivors have lower level of physical activity at one year post stroke despite having mild physical impairments. Rehabilitation strategies to promote physical activities should be implemented early to take advantage on the benefits of cardiovascular fitness as secondary prevention of stroke.
The effect of internet-based telehealth nursing on the quality of life in patients with atrial fibrillation and stroke
Authors: Zhang Meng , Guo Wei
Published: December 2023

Background: The purpose of this study is to determine if patients with atrial fibrillation and stroke can benefit from receiving care at home under the supervision of remote specialist nurses through internet-based telehealth nursing.
Methods: We selected a total of 168 patients with atrial fibrillation and stroke, who were treated in our hospital from January 2018 to December 2019. The patients were divided into a traditional at-home self-help nursing group (the control group) and an internet-based telehealth nursing group involving specialist nurses based on the post-discharge convalescence nursing modes (the experimental group). The patients were followed up and observed for 12 months, and the survival rate, readmission rate, daily life activities, limb motor ability, psychological state, cardiac function and rhythm control, adverse event rate, and the nursing satisfaction of the patients and their families were evaluated for the two different nursing modes.
Results: Compared with traditional at- home nursing, internet-based telehealth nursing provided by specialist nurses resulted in a significant improvement in the survival rate of patients. Additionally, the readmission due to atrial fibrillation or stroke was significantly reduced, the daily activities and limb motor ability were significantly improved, the patients’ anxiety and depression were reduced, and the cardiac function index and rhythm control showed obvious improvement. In addition, the rates of bedsores and minor hemorrhage events were lower, and the nursing satisfaction levels of the patients and their families were significantly higher.
Conclusion: Patients with atrial fibrillation and stroke benefit greatly from internet-based telehealth nursing provided by specialized nurses, both in terms of prognosis and quality of life. As a result, this approach to nursing care deserves wider adoption and dissemination.
Cyclic vomiting syndrome plus accompanying Ross syndrome: More than a peripheral autonomic dysfunction
Authors: Gürsoy Gizem , Tutkavul Kemal , Yaşar Şirin
Published: December 2023

Ross syndrome is a rare syndrome consisting of areflexia, tonic pupil and segmental anhidrosis. It has been shown to accompany neuropsychiatric diseases such as psychiatric disorders, headache, and epilepsy. We report here a 19-year-old female who was the first case in which cyclic vomiting syndrome plus was shown to accompany Ross syndrome.
Parsonage-Turner syndrome after COVID-19 vaccination: A case report
Authors: Deveci Şule
Published: December 2023

Parsonage-Turner syndrome (PTS) is one of the rare peripheral neuropathies that causes sudden and severe pain followed by sensory defect, loss of muscle strength and atrophy in the upper extremities. If a patient experiences persistent shoulder pain after COVID-19 vaccination, followed by weakness and sensory changes in the extremity, Parsonage-Turner syndrome should be considered in the differential diagnosis. We report a rare case of PTS that developed after COVID-19 vaccination.
Effect of cold compression before botulinum neuro- toxin injection in hemifacial spasm
Authors: Tantirittisak Tasanee , Peamnapatch Dhanachanvisith
Published: December 2023

Objectives: To compare the effect of using cold compression before injecting botulinum toxin (BTX) versus not using cold compression, on pain and bleeding at the injection site, efficacy and the quality of life of patients with hemifacial spasm (HFS).
Methods: A prospective, randomized, case crossover design was employed. One hundred fifty-nine (159) patients who were diagnosed as having primary HFS with BTX treatment in the botulinum toxin clinic were randomized during the period from May 2017 to November 2017. Patients were divided into two groups – with cold compression and without cold compression before BTX injection and then evaluated for the severity and frequency of HSF using the Jankovic Rating Scale and quality of life questionnaire. Immediate complications after injection such as pain and bleeding were also assessed.
Results: Cold compression before BTX injection significantly decreased the severity and frequency of HFS (p<0.001). Pain in cases where cold compression was used before BTX injection was significantly lower than in those cases not receiving cold compression (p<0.001). Satisfaction scores and bleeding were significantly different (p<0.001). Quality of life was significantly improved after treatment with BTX (p<0.001).
Conclusion: Cold compression before BTX injection can improve the efficacy of treatment by reducing severity and frequency. This study confirms previous studies that using cold compression before BTX injection results in a good outcome in relation to satisfaction and bleeding. No significant complications were found. Additionally, BTX injection can also improve quality of life in hemifacial spasm patients.
Multiple symmetric lipomatosis and MERRF: A case from Turkey
Authors: Alpaydin Baslo Sezin , Tekin Betul , Gundogdu Unverengil Gokcen , Erdogan Mucahid , Yusifov Mahir , Atakli Dilek
Published: December 2023

The association of multiple symmetric lipomatosis (MSL) and mitochondrial disorders is not frequent. We report a male patient with multiple lipomas, hearing loss, progressive limb-girdle muscle weakness, neuropathy and myoclonia. Serum creatinine kinase was mildly elevated. Electromyography revealed sensory axonal polyneuropathy and myopathy with sparse denervation. A muscle biopsy showed ragged-red fibers. Next-generation DNA sequencing revealed a heteroplasmic m.8344A>G mutation in the MT-TK gene. To the best of our knowledge, this is the first patient to be reported from Turkey with a diagnosis of MSL and myoclonic epilepsy with ragged red fibers (MERRF).
Clinical exome sequencing reveals an important role for clinical diagnosis of intellectual disability with definition of seven novel variants
Authors: Yalcintepe Sinem , Gorker Isik , Bozatli Leyla , Sezginer Guler Hazal , Zhuri Drenushe , Demir Selma , Atli Emine Ikbal , Atli Engin , Eker Damla , Gurkan Hakan
Published: December 2023

Intellectual disability can be defined as a significantly below-average general mental function, accompanied by environmental adaptation and behavioural deterioration. Patient files of 87 children with intellectual disability were evaluated in this study. After clinical exclusion criterias, clinical exome sequencing was performed for 25 of 87 intellectual disability cases with a massively parallel targeted sequencing method. Seventeen variants in the genes MBOAT7, KDM5C, TUBB3, MAN1B1, GFAP, CACNA1A, BCOR, LMNA, LBR, ALS2, ENPP1, UBE3A, TRAPPC9, HSPG2, AFF2, NLGN4, and SOX10 were identified in 14 of 25 patients (56%). Seven of the 17 variants (41.1%) were novel in the genes KDM5C, BCOR, UBE3A, TRAPPC9, AFF2, NLGN4, and SOX10. Seven cases (7/25, 28%) had a definite diagnosis of intellectual disability with their pathogenic variants. The high rate of variant detection (56%) in the current study shows that multiple gene analysis plays an essential role in diagnosing the uncertain etiology of intellectual disability. This study also presents seven novel variants, which are first reported.
Serum YKL-40 (chitinase 3-like protein 1) levels in migraine patients during an attack
Authors: Horasanli Bahriye , Caliskan Sak Zeynep , Ozsahin Aysun , Ucar Karabulut Keziban
Published: December 2023

Objectives: The aim of this study was to investigate YKL-40 in migraine patients during migraine attacks.
Methods: In this prospective study, 30 migraine patients with aura (MWA) and 30 migraine patients without aura (MWOA) who presented to the Neurological Outpatient Department of Konya City Hospital during a migraine episode as well as 28 healthy controls were included. According to the manufacturer’s recommendations, serum YKL-40 levels were determined using an ELISA kit (FineTest). Statistical analysis of the data was performed with the IBM SPSS version 20.0 program.
Results: The mean gender and age were similar between groups (p>0.05). The serum YKL-40 level was 3575 ± 604.975 pg/ml in the MWA group, 3339 ± 492.689 pg/ml in the MWOA group and 3190 ± 544.018 pg/ml in the control group. YKL-40 levels were significantly higher in MWA than in the control group (p=0.028). YKL-40 levels were similar in the MWA and MWOA groups (p=0.302). No significant difference was found between the group with MWOA and the control group (p=0.915).
Conclusion: Although YKL-40 levels are increased in patients with migraine with aura during an attack, comprehensive studies with a larger sample are needed to clarify the relationship between YKL-40 and migraine.
Cumulative seizure occurrence and the predictors of seizure in low- and high-grade gliomas
Authors: Audrey Christine , Lim Kheng Seang , Chan Chet-Ying , Kumar Thinisha Sathis , Hou Rui Jia , Fong Si Lei , Narayanan Vairavan , Wan Anuar Wan Muhammad Afnan , Tan Chong Tin
Published: December 2023

Objective: We aimed to determine the cumulative seizure occurrence, 1-year, and 5-years of preoperative seizures in gliomas, and an update on the predictors.
Methods: This was a retrospective analysis of 239 patients with histopathologically confirmed gliomas in University Malaya Medical Centre, Malaysia, between 2008-2020. Kaplan-Meier curves were used to determine the cumulative incidence of seizures. Logistic regression was performed to determine the predictors of preoperative seizures.
Results: A total of 80/239 patients (33.5%) had preoperative seizures. They were more commonly seen in those with younger age of presentation (40.0% in those <40 years old vs. 26.9% in ≥40 years old, p<0.05) and low-grade tumors (42.2% vs. 28.8% in high-grade tumors). Those with cortical involvement, especially the frontal lobe, or without focal deficit, headache, nausea, or vomiting were more likely to have seizures preoperatively. Logistic regression identified three significant predictors for preoperative seizure: absence of focal deficits at presentation (OR 6.090, 95% CI 3.110-11.925, p<0.001), cortical location (OR 3.834, 95% CI 1.363-10.786, p<0.05) and absence of headache at presentation (OR 2.487, 95% CI 1.139-5.431, p<0.05). The cumulative incidence of seizure was 29% at one year and 32% at 5-year for gliomas. Specifically, the seizure incidence was higher in low-grade gliomas (39% at 1-year) and certain tumor types such as ganglioglioma (50%), oligodendroglioma (48%), and astrocytoma (45%).
Conclusion: The cumulative incidence of preoperative seizures in low-grade gliomas and certain tumor types is high. The predictors included cortical involvement and absence of focal neurological deficit or headache at presentation.
Association between language function and body composition characteristics in patients with subacute left hemispheric stroke
Authors: Han Soo Jeong , Suh Jee Hyun
Published: December 2023

Background & Objectives: Stroke-related sarcopenia and language disorder are main sequelae of stroke. The aim of this study is to evaluate the association between language function and body composition characteristics in patients with subacute left hemiplegic stroke.
Methods: Body mass index, skeletal muscle index (SMI), and body fat percentage using bioimpedance analysis, hand grip strength, and Medical Research Council (MRC) sum score were evaluated. Language function was evaluated using the Western Aphasia Battery (WAB). A partial correlation analysis was used to assess the relationship between body composition and language function.
Results: A total of 54 patients with subacute left hemispheric stroke were enrolled in the study. The aphasia quotient (AQ) of WAB was significantly correlated with SMI, body fat percentage, MRC-sum score, MRC-sum score of unaffected side and hand grip strength. In the multiple regression analysis after adjusting for age and sex, the AQ of WAB was significantly correlated with SMI.
Conclusions: Skeletal muscle index showed highest correlation with language function in patients with left hemispheric stroke.
Pharmacogenomics knowledge within Neurology: A brief survey amongst physicians
Authors: Narasimhalu Kaavya , Soo Joel , Shen Jia Yi , Wong Pei Shieen
Published: December 2023

Pharmacogenomics has emerged as a tool to optimise treatment. Many neurologists encounter drugs with pharmacogenomic associations with unclear guidelines. We therefore aimed to determine the knowledge, attitudes, and barriers to implementing pharmacogenomics in clinical practice within a neurology unit. We developed and administered a survey on pharmacogenomics to physicians working in a neurology unit. Three drug-gene pairs clinically relevant to neurology were presented as case scenarios to assess physicians’ perceived competency, attitudes, and risks towards pharmacogenomics. Thirty-two (27.4%) physicians responded to the survey. Respondents were most confident about activities involving the HLA-B*15:02 test, followed by the CYP2C19 test, and lastly the CYP2C9 test. However, perceived competency in drug-drug-gene interactions was consistently low for all three tests. Referring to the product information leaflet ranked highest in usefulness, followed by local practice guidelines. In conclusion, local clinical guidelines and training on the clinical applications of pharmacogenomics are important to facilitate the implementation of pharmacogenomics.
Depression as comorbidity in Sundanese epilepsy patients
Authors: Tandiawan Fedrick , Gunadharma Suryani , Gamayani Uni , Ong Anam , Rizal Ganiem Ahmad , Sobaryati  , Iskandar Shelly
Published: December 2023

Background: Depressive disorder is a common psychiatric comorbidity in patients with epilepsy (PWE). This health condition is prevalent among the Sundanese who have a calm and polite character, with a tendency to hide their feelings, which is associated with an increased risk of depression.
Methods: This cross-sectional study aimed to determine the prevalence of major depressive disorder (MDD) and the associated factors among Sundanese PWE. The study was carried out in the neurology outpatient clinic at Hasan Sadikin General Hospital Bandung, consisting of the Sunda ethnic group as the majority of patients. Self-stigma degree was measured using the Indonesian version of Internalized Stigma of Epilepsy (ISEP) questionnaire, while depression symptom was screened through the Indonesian version of Neurological Disorders Depression Inventory for Epilepsy (NDDI-E). Subsequently, patients who had depression symptoms were referred to a psychiatrist to confirm whether their conditions matched the criteria of MDD according to the Diagnostic and Statistical Manual of Mental Disorder-5.
Results: The prevalence of depressive symptoms in Sundanese epilepsy patients was found to be 18.4%, and MDD was 6.8% among 103 patients included in this study. Many PWE with MDD were not married, had uncontrolled seizures, used polytherapy anti-seizure medication, and exhibited a higher degree of self-stigma.
Conclusion: In this study, the prevalence of MDD was found to be 6.8% among a cohort of Sundanese PWE. A significant relationship was also observed between MDD and several factors, including single status, uncontrolled seizure, polytherapy, and a higher degree of self-stigma.
Evaluation of inpatients neurology consultations in the department of gynecology, obstetrics, and reproductive medicine of a tertiary hospital in Turkey
Authors: Agircan Dilek , Cekic Murat , Uyanıkoglu Hacer , Gesoğlu Demir Tülin , Ethemoglu Ozlem
Published: December 2023

Background & Objective: It is important to be aware of hormonal changes in neurological disease in neurology training. We aimed to investigate the most common disorders which resulted in the clinicians from the Department of Gynecology, Obstetrics, and Reproductive Medicine (GORM) to ask for neurology consultation from the Department of Neurology.
Methods: All the neurology consultations requested from the Department of GORM between 2015 and 2023 at Harran University Hospital, Sanliurfa, Turkey, were retrospectively evaluated with regard to demographic characteristics, the reason for referral, neurologic diagnoses, and treatment, imaging features. SPSS statistical software version 22 (IBM Inc. NC, USA) was used to perform all statistical analyses.
Results: There were 333 patients with a mean age of 32.5 years (range 17-68) seeking consultations; 287 had obstetric problems, and 46 had gynecological issues. In the obstetric group, pre-eclampsia and Posterior Reversible Encephalopathy Syndrome (PRES) were the most frequent final neurological diagnoses, while headache and acute cerebrovascular disease were the most common frequent problems in the gynecological group. The number of consultations rose from 23 in 2015 to 66 in 2022. The predicted rate of final diagnosis of GORM residents was 58%. The neurologist’s contribution has substantial influence on the management of 208 (62%) patients.
Conclusion: Neurologists have a significant contribution to the management of GORM inpatients. In neurological training, importance should be given to the effect of hormonal changes on neurological diseases in neurology training.
Novo ensino médio e projeto de vida: libertação ou adaptação?
Authors: Ferreira João Roberto Resende , Da Silva Cláudio José
Published: December 2023

O artigo apresenta uma reflexão sobre o papel do componente curricular Projeto de Vida, no contexto das reformas educacionais, realizadas para atender às demandas do capitalismo em sua fase neoliberal. A esse propósito, apresentamos uma reflexão sobre os fatores que influenciam na definição das políticas educacionais, e no componente curricular projeto de vida, bem como na forma como ele está sendo apresentado e implementado no Estado de Goiás. A metodologia utilizada foi a pesquisa bibliográfica em autores como Marx (2013), Meszáros (2008), Saviani (1999) e documental tendo como referência a Constituição de 1988, a Lei de Diretrizes e Bases da Educação de 1996, a Base Nacional Comum Curricular (BNCC) e Documento Curricular para Goiás – Etapa Ensino Médio (DC-GOEM). Nosso pressuposto é que a educação é parte integrante de uma sociedade, e como tal ela recebe influência desta estrutura ao mesmo tempo que a influencia.
Análise da aplicabilidade dos artefatos gerenciais utilizados nos meios de hospedagem da cidade de Rosana – SP
Authors: Ginez Tainá de Moraes , Da Costa Araceli Mascarenhas , Giacomini Wesley Felipe Gois , Da Silveira Vítor Cardoso , Eduardo Antonio Sérgio , Schotten Paulo César
Published: December 2023

O presente estudo buscou analisar a aplicabilidade dos artefatos gerenciais nos meios de hospedagem do município de Rosana, interior do estado de São Paulo. Por meio de conceitos relacionados à gestão empresarial, contabilidade gerencial e seus artefatos, foram realizadas entrevistas semiestruturadas presenciais com quatro gestores e proprietários no período de agosto/2022. A pesquisa possui abordagem qualitativa com transcrição de entrevistas e utilização da técnica de pesquisa de análise de conteúdo para apresentação dos fatores que influenciam a escolha e a forma que os artefatos são utilizados nos meios de hospedagem. Dentre os principais resultados, tem-se a ausência de gestão especializada no setor hoteleiro e a adoção dos artefatos gerenciais baseada na prática e na experiência de anos de trabalho em um ambiente interiorano. Os artefatos gerenciais mais utilizados nos estabelecimentos estudados são os tradicionais – Custeio por Absorção, Orçamento e Retorno sobre o Investimento. Dentre os artefatos de contabilidade gerencial modernos, destaca-se a forte presença do planejamento estratégico.
Sistema de informação geográfico aplicado na espacialização de ocorrência de dengue em São Luís de Montes Belos-GO
Authors: Paixão Júnior Marcelo Alves , Giongo Pedro Rogerio , Cardoso Robson Lopes , Coelho Karyne Oliveira , Ponciano Isaac de Matos , Corioletti Níbia Sales Damasceno , De Oliveira Márcio Sebastião , Backes Clarice
Published: December 2023

Este estudo objetivou mapear a área urbana de São Luís de Montes Belos quanto a incidência de dengue no período de 2008 a 2017 com vistas a fornecer subsídios ao Programa de Vigilância e Controle da doença no município. Cada caso foi identificado por bairro de acordo com informações obtidas pelo Sistema de Informação de Agravos de Notificação. Esse banco de dados foi correlacionado a fatores geográficos e espacializados por meio do geoprocessamento. Foram elaborados mapas temáticos da incidência dos casos suspeitos e confirmados de dengue em cada bairro e ano; realizou-se a correlação desses índices com os níveis de precipitação mensal entre os anos de 2011 a 2017. Após a análise de dados, alguns fatores que mais influenciam na incidência desse agravo foram observados sendo eles: volume de chuva, alternância de vírus e região com maior densidade populacional. Entre os itens o que houve maior significância foi o índice pluviométrico, sendo o fator determinante no aumento da ocorrência, principalmente nos dois primeiros trimestres do ano. De acordo com espacialização dos casos o avanço da doença pode ter seu avanço bloqueado com maior eficácia, pois medidas preventivas diversas podem ser adotadas nos pontos críticos de todo município.
The Impact of Pricing, and Product Quality on Purchasing Decisions: Role Digital Marketing as a Moderating
Authors: Herispon Herispon , Sudriana Putri
Published: December 2023

This study attempts to ascertain how factors related to product quality, competitive pricing, and digital marketing affect sales volume and how digital marketing modifies the relationship between sales volume and purchasing decisions at PT Sang Hyang Seri Marketing Branch Riau. In this study, information was gathered from 130 respondents via questionnaires, and SEM was used for analysis. Found that Digital marketing did not show any support when employed as a moderating variable between purchase decisions and sales volume, while all other variables studied had a substantial beneficial effect on purchasing decisions and sales volume, both concurrently and separately
Alexina B., Contemporary Opera as Consolation
Authors: Fernández Rosa , Sound Stage Screen
Published: December 2023

Review-Essay of the opera Alexina B. Music by Raquel García-Tomás, libretto by Irène Gayraud, stage direction by Marta Pazos. Gran Teatre del Liceu, Barcelona, March 2023.
Prediction of Cybercrime using the Avinashak Algorithm
Authors:   Research Scholar, Department of Information Technology, Lincoln University College, Malaysia., Rajeev Haritha , Chakkaravarty Dr. Midhun ,   Assistant Professor, Department of Information Technology, Lincoln University College, Malaysia.
Published: December 2023

The detection and prevention of phishing websites continue to be major obstacles in the continually changing field of cybersecurity. Phishing attacks continue to use sophisticated methods to exploit user vulnerabilities, thus it is vital to predict and identify these malicious websites. Traditional techniques for detecting phishing sites frequently rely on rule-based and domain-based approaches, which might not adequately capture the dynamic nature of phishing attacks. The Avinashak Crime Prediction Algorithm appears to be a proprietary or specialized algorithm not widely known in the machine learning community. Its details and working principles are not publicly available, which makes it challenging to provide a detailed explanation without additional information.