bluuebunny/crossref_metadata_2025 huggingface dataset:
Geographically Weighted Logistic Regression Applied to Credit Scoring Models
Authors: Albuquerque Pedro Henrique Melo ,   Universidade de Brasília,  Brazil, Medina Fabio Augusto Scalet , Silva Alan Ricardo da ,   Universidade de Brasília,  Brazil
Published: January 2017

Abstract This study used real data from a Brazilian financial institution on transactions involving Consumer Direct Credit (CDC), granted to clients residing in the Distrito Federal (DF), to construct credit scoring models via Logistic Regression and Geographically Weighted Logistic Regression (GWLR) techniques. The aims were: to verify whether the factors that influence credit risk differ according to the borrower’s geographic location; to compare the set of models estimated via GWLR with the global model estimated via Logistic Regression, in terms of predictive power and financial losses for the institution; and to verify the viability of using the GWLR technique to develop credit scoring models. The metrics used to compare the models developed via the two techniques were the AICc informational criterion, the accuracy of the models, the percentage of false positives, the sum of the value of false positive debt, and the expected monetary value of portfolio default compared with the monetary value of defaults observed. The models estimated for each region in the DF were distinct in their variables and coefficients (parameters), with it being concluded that credit risk was influenced differently in each region in the study. The Logistic Regression and GWLR methodologies presented very close results, in terms of predictive power and financial losses for the institution, and the study demonstrated viability in using the GWLR technique to develop credit scoring models for the target population in the study.
THE REPRESENTATION OF BASQUE IMMIGRATION IN AMERICAN CINEMA: Wild is the Wind (1959) or the Quest for Elucidating What a Basque Is
Authors: ALVAREZ-GILA Oscar
Published: January 2017

ABSTRACT In previous studies I have presented a general overview of the way American Cinema depicted Basque people, and especially Basque immigrants in the American West, and its evolution since the times of silent cinema to our days. In this article I will analyse one of the very first films in which a Basque character is presented, not in a secondary role, but as a protagonist. Wild is the Wind (George Cukor, 1959) represents also one of the first approaches to the representation of Basque identity by a Hollywood A-movie (this is, a film with a high budget, produced by major company, with the participation of well-known actors and actresses under the control of a renowned director) Firstly, I will summarize the main elements that characterized and conditioned the image of Basque immigrants, and Basque people as a whole, up to the decade of 1990 in the cinema of Hollywood. Secondly, I will describe the process of ellaboration of the film since its first steps, highlighting when, why and by whom was decided to introduce a Basque character in the plot. Finally, I will analyze how this Basque character is depicted in the film, both by the means of external (race, language, clothes...) and internal features (mainly, the dialogues), putting them in the context of previous and contemporary films and tv movies in which Basque characters also appeared.
Contact angles and wettability: towards common and accurate terminology
Authors: Marmur Abraham , Della Volpe Claudio , Siboni Stefano , Amirfazli Alidad , Drelich Jaroslaw W.
Published: January 2017

Much interest has recently been focused on contact angles, wetting and non-wettable surfaces as is evidenced by the rapid pace and sheer number of papers published in recent years. However, in many cases there exist misconceptions and misuses of terminology, leading to misinterpretation of experimental contact angles, measurements of which deceptively appear to be simple. Terms describing contact angles, wettability, superhydrophobicity and similar other terminology are loosely used. In this contribution, key terms used in relation to contact angles are defined precisely based on the accumulative knowledge from the surface chemistry community over the last decades. The definitions provided are scientifically rigorous to avoid any ambiguity and confusion. The theoretical considerations underlying these definitions are only briefly mentioned, with references to the relevant papers. Interpretation and meaning of the measured contact angles can be made simpler if the basic concepts are clearly understood and theory-based indications are applied. The clarity of definitions should make data interpretation and comparison easier for future contributions to journals, including this journal.
Transformasie en die universiteitswese
Authors: Venter F
Published: January 2017

"Transformasie" word nie in wetgewing of die Grondwet omskryf nie, maar die beleids-dokumente van die regering en die ANC beklemtoon dit sterk as doelwit. Die motivering vir transformasie word in die konteks van die "National Democratic Revolution" onverbloemd op grond van Marxisties-Leninistiese denke gemotiveer. Hoewel dit ongetwyfeld nie "polities korrek" is om die voortgesette benutting van die kommunistiese taal waarvan die ANC se beleidsdokumente deurdrenk is, te bevraagteken nie, kan ook nie eenvoudig aanvaar word dat dit maar net 'n leë woordespel is nie. In sowel die 1993- en 1996-weergawes van die Grondwet word edele oogmerke ter ondersteuning van fundamentele sosiale en ekonomiese verandering gestel, wat - indien dit verwerklik sou kon word - die komplekse en gekonflikteerde Suid-Afrikaanse samelewing kan omskep in n stabiele burgery met gemeenskaplike verwagtinge van sosiale geregtigheid en stabiliteit. Die huidige regswetenskaplike behandeling van die transformasiebegrip dra nie veel by tot die verheldering van die betekenis daarvan nie. Die wetgewing en beleidsdokumente waarin daar sprake is van transformasie, voorsien ook nie definisies nie en die howe se vertolking daarvan is nie eenduidig nie. Daardeur is die begrip blootgestel aan misbruik vir ideologiese doeleindes, wat die belofte van mislukking inhou wanneer die oorblywende hulpbronne uitgeput is. Onomskrewe transformasie word ook vir die universiteitswese voorgeskryf, en die jongste wysiging van die betrokke wetgewing beoog om aan die Minister die gesag te gee om eensydig "transformasiedoelwitte" aan universiteite voor te skryf en af te dwing. 'n Verandering van die heersende magspatrone wat bevryding van die NDR kan meebring, kan die behoud en positiewe uitbou van die oorblywende eilande van uitnemendheid in die hoëronderwyssektor meebring.
"Loving thy neighbour" in times of violence: Social cohesion and collective efficacy in South Africa
Authors: Barolsky V
Published: January 2017

This article engages with the problematic of violence and its relationship to conditions of solidarity at a local level in the newly democratised nation-state of South Africa. It explores this question through the concept of social cohesion, which has become a significant part of South African discourse over the past decade and has been the object of policy concern in the global north since the 1990s. More recently the concept of social cohesion has been linked to the question of violence through the theory of collective efficacy, which sees social cohesion enacted in support of the "common good" as functioning as a critical "protective" factor against violence. The paper interrogates these international and local discourses around social cohesion and its relation to violence through an ethnographic examination of the empirical conditions of solidarity and violence in one township, Khayelitsha, in the Western Cape, South Africa. The article reveals the dissonances between the material conditions in Khayelitsha, international discourses on social cohesion and the South African state's aspirations towards new forms of civic solidarity founded on a Constitutionally defined "common good". Instead collective, informal, and sometimes violent forms of social order based on communitarian values and practices, displace or contest the state's law and shape forms of sociality that offer both extraordinary support and the possibility of spectacular violation.
INFLUÊNCIA DOS ENXAGUATÓRIOS BUCAIS NA RUGOSIDADE SUPERFICIAL DE UMA RESINA COMPOSTA
Authors: Aragão Gabriela Sampaio , Falcão Renata Martins , Durães Íris , Bezerra Rebeca Barroso
Published: January 2017

A lisura superficial é uma importante característica do material restaurador. Dessa forma, a resina composta deve apresentar níveis de rugosidade baixos para dificultar a retenção de biofilme dental. A alteração da superfície das restaurações de resina composta pode estar associada às bebidas e alimentos ácidos, aos componentes da saliva, aos métodos de acabamento e polimento, assim como a ação de agentes clareadores, enxaguatórios e fluoretos. Objetivo: Avaliar o efeito de enxaguatórios bucais na rugosidade superficial de uma resina composta nanoparticulada por meio de uma avaliação quantitativa. Materiais e Métodos: Foram confeccionados 48 corpos de prova com a resina composta FiltekTM Z350 XT, divididos em 4 grupos (n=12): água destilada, Colgate® Plax, Oral B® e Listerine®. Para a confecção dos corpos de prova utilizou-se uma matriz retangular com perfurações, cada uma medindo 0,8cm de diâmetro interno por 0,2cm de espessura. Os corpos de prova foram imersos em 50ml de uma dessas substâncias, por 12 horas, equivalente a um ano de uso diário da solução por 2 minutos. Em seguida, foram armazenados em água destilada até a leitura no rugosímetro. Os dados encontrados foram tratados estatisticamente pelos testes de ANOVA e Tukey, com nível de significância de 95%. Resultados: Foi observada diferença estatisticamente relevante entre o grupo controle e o Listerine® (p= 0,03). Ao comparar as médias de rugosidade das diferentes marcas de enxaguatórios, não houve diferença estatisticamente significante (p > 0,05). Conclusões: Dentre os enxaguatórios bucais testados, apenas o Listerine® provocou aumento estatisticamente significante na rugosidade superficial da resina composta utilizada.
PERFIL EPIDEMIOLÓGICO DA HANSENÍASE EM MUNICÍPIO DO INTERIOR PAULISTA
Authors: Femina Luana Laís , Nardi Susilene Maria Tonelli , Donda Priscila , Lozano André Willian , Lazaro Camila , Paschoal Vânia Del’Arco
Published: January 2017

Introdução: Mesmo com os acordos realizados com a Organização Mundial de Saúde para atingir a meta de eliminação dahan-seníase em 2015, no Brasil a detecção é considerada alta. Para a eliminação são necessários o diagnóstico precoce,tratamento gratuito, cura, controle de comunicantes, prevenção de deficiências físicas e ações de educação em saúde paraprofissionais e para evitar o preconceito com os pacientes. Objetivo: Analisar a situação epidemiológica de um município dointerior paulista e o perfil das pessoas com hanseníase. Material e Métodos: Estudo descritivo retrospectivo, cuja coleta dedados foi realizada pelo Sistema de Informação de Notificação de Agravos, prontuários e fichas de enfermagem, dos anos de2001 a 2013. Resultados: Do total de 98 pacientes com hanseníase, 55,1% eram do gênero masculino, 45,9% erammultibacilares e 62,2% tinham baciloscopia negativa. A detecção de casos foi considerada alta em 2002 (27,87/100.000habitantes) e baixa em 2013 (1,76,/100.000 habitantes) e a prevalência veio diminuindo no decorrer dos anos de 4,1/10.000habitantes em 2003 para 0,35/10.000, em 2013. O indicador em menores de 15 anos oscilou, sendo considerado muito alto em2011. A avaliação de incapacidades foi precária no diagnóstico (36,7%) e na alta (12,3%) e 40,5% dos casos foramdiagnosticados com alguma deficiência. Conclusão: A frequência de casos multibacilares com deficiências e a oscilação anualna detecção, prevalência e em menores de 15 anos remetem a uma fragilidade no controle da doença pelo serviço de saúde eevidenciam necessidade de se organizar a gestão do cuidado e as ações de prevenção.
IDENTIFICAÇÃO DOS RISCOS OCUPACIONAIS E MEDIDAS PROTETIVAS DE SEGURANÇA LABORAL: ESTUDO COM GRUPO DE MOTOTAXISTAS
Authors: Lima Marcio Medeiros , Linhares Ana Cristina Fernandes , De Farias Márcia Monteiro , Medeiros Hellen Renatta Leopoldino , Camboim Francisca Elidivânia De Farias , De Sousa Milena Nunes Alves
Published: January 2017

Introdução: A motocicleta vem se tornando um meio de transporte socialmente relevante, em especial, para a classe trabalhadora que utiliza esse veículo para prestação de serviços de condução e/ou serviços de entrega. Nesse contexto, inserem-se os profissio-nais mototaxistas e motoboys que representam uma importante opção de sobrevivência pela autonomia na realização do trabalho. Objetivo: Identificar os riscos ocupacionais e as medidas protetivas de segurança no trabalho entre um grupo de mototaxistas. Casuística e Métodos: Trata-se de uma pesquisa descritiva com uma abordagem quantitativa. A amostra foi composta por 50 profissionais. A coleta foi realizada no mês de março de 2016. Os dados foram analisados a partir de estatística descritiva. Resul-tados: Todos são do sexo masculino, 48% com ensino médio completo. O risco ocupacional mais citado pelos profissionais foram os acidentes de trânsito, seguidos por assalto. O uso de equipamentos de segurança foi considerado muito importante por 54% dos profissionais. Conclusão: é possível confirmar que o objetivo do trabalho foi alcançado, visto que os profissionais reconhecem alguns dos riscos as quais estão expostos como: risco para acidente de trânsito, risco para o desenvolvimento de câncer, entre outros. Os profissionais fazem uso equipamentos de proteção individual, embora não todos os equipamentos recomendados à sua prática trabalhista e reconhecem que o uso desses equipamentos pode minimizar as lesões relacionadas a acidentes de trabalho.
CARACTERIZAÇÃO DOS PACIENTES COM ACIDENTE VASCULAR ENCEFÁLICO ATENDIDOS NA EMERGÊNCIA
Authors: Ribeiro Renato Mendonça , Rodrigues Clea Domitildes Soares , Bertolin Daniela Comelis , Ribeiro Rita De Cassia Helú Mendonça , Cesarino Claudia Bernardi , Kusumota Luciana , Fantini Joseli Ferreira Angelini
Published: January 2017

Introdução: O Acidente Vascular Encefálico se caracteriza por déficit neurológico súbito, de origem vascular, podendo ser isquêmico ou hemorrágico. Objetivos: Caracterizar os pacientes com Acidente vascular encefálico atendidos na emergência de um Hospital de ensino e verificar os desfechos clínicos desses pacientes. Material e Métodos: Desenvolveu-se um estudo epidemiológico observacional, retrospectivo, de análise de prontuário eletrônico, que utilizou a estatística descritiva e o coeficiente de Spearman. Resultados: Fizeram parte da amostra 1.095 prontuários de pacientes com diagnóstico de acidente vascular encefálico, atendi-dos na emergência no período de 01 de janeiro a 31 de dezembro de 2014. Houve predomínio de pacientes do sexo masculino (51,9%); brancos (83,7%); com até oito anos de estudo (64,4%); casados/união estável (62,2%); procedentes de outras cidades do estado de São Paulo (60,8%); com mais de 60 anos (68,3%); que precisaram de internação (69,3%); atendidos pela neurocirurgia (52,3%); que fizeram tomografia computadorizada (55,8%); e tiveram como principal desfecho a alta médica (63,5%). Pode-se observar correlação direta e estatisticamente significativa, p=0,004, com o desfecho internação, indicando que as pessoas mais idosas necessitem mais tempo de internação. Conclusão: A maioria dos pacientes atendidos era homens, idosos, casados, com boa escolaridade, atendidos pela neurocirurgia, internados e o principal desfecho clínico foi a alta médica por melhora.
PREVALÊNCIA E FATORES ASSOCIADOS AO TEMPO EXCESSIVO ASSISTINDO TV EM ADOLESCENTES
Authors: Pelegrini Andreia , Pinto André De Araújo , Claumann Gaia Salvador , De Angelo Hector Cris Colares , Silva João Marcos Ferreira de Lima , Petroski Edio Luiz
Published: January 2017

Introdução: Atividades, como assistir à TV, o uso do computador, trabalhos de mesa e ficar sentado em momentos de socialização são consideradas como comportamentos sedentários. Dentre tais comportamentos, o tempo excessivo em frente à TV é associado ao aumento no risco de desenvolvimento de inúmeras doenças. Preocupantemente, adolescentes brasileiros estão cada vez mais envolvidos nesse comportamento (assistir à TV). Objetivo: Estimar a prevalência de tempo excessivo assistindo TV e suas possíveis associações com fatores sociodemográficos, status do peso e atividade física em adolescentes. Casuística e Métodos: Participa-ram 1127 adolescentes de ambos os sexos, de 14 a 19 anos, de escolas públicas estaduais de Florianópolis-SC. Os adolescentes informaram o tempo de permanência assistindo à TV (sendo considerado tempo excessivo > 2h/dia) e se possuíam TV no quarto. Foram coletadas informações sobre sexo, idade, nível econômico e nível de atividade física. Foram aferidas as medidas de massa corporal e estatura para cálculo do índice de massa corporal e posterior classificação quanto ao status do peso. Resultados: Dos adolescentes, 53,9% (58,8% das moças e 46,4% dos rapazes) assistiam à TV por tempo excessivo. Rapazes e moças que possuíam TV no quarto apresentaram maior chance de permanência excessiva assistindo ao eletrônico (OR= 1,84; IC95%= 1,05-3,24 e OR= 1,58; IC95%= 1,07-2,32, respectivamente). Moças com níveis insuficientes de atividade física apresentaram maior chance de assistir TV por tempo excessivo (OR= 1,56; IC95%= 1,05-2,32). Conclusão: Mais da metade dos adolescentes permanecia por tempo excessivo assistindo à TV. Possuir TV no quarto foi um fator associado ao desfecho para ambos os sexos. Apenas para as moças, o nível de atividade física esteve associado ao tempo excessivo assistindo à TV.
HIV/AIDS: RELAÇÃO DOS NÍVEIS DE LINFÓCITOS TCD4+ E CARGA VIRAL COM O TEMPO DE DIAGNÓSTICO
Authors: Furini Adriana Antônia da Cruz , Neves Evellyn Ribeiro , Ferreira Gabriela Alvez , Rodrigues Jean Francisco , Jorge Luciana Souza , Machado Ricardo Luiz Dantas
Published: January 2017

Introdução: A Síndrome da Imunodeficiência Adquirida é a manifestação causada pelo Vírus da Imunodeficiência Humana, caracterizada por um processo crônico progressivo. O tempo de sobrevida é relacionado à qualidade do serviço em saúde, diag-nóstico precoce, inicialização da Terapia Antirretroviral segundo Consensos pré-estabelecidos, exames laboratoriais de rotina e monitorização da evolução clínica da doença. A relação entre o sistema imunológico do paciente e o vírus do HIV possibilita ao médico avaliar a terapêutica. Objetivo: Avaliar níveis de carga viral e linfócitos TCD4+ (LTCD4+), de acordo com o tempo de diagnóstico da doença em anos. Material e Métodos: Estudo retrospectivo constituído de 182 prontuários do Ambulatório de Do-enças Infecto-parasitárias do Hospital de Base/FUNFARME (ADIPHB) de São José do Rio Preto/SP. Foram analisados: tempo de doença, contagem dos primeiros e últimos índices de LTCD4+ e de carga viral. Resultados: Dos 182 prontuários avaliados, 84,07% tinham entre 8,1 a 18 anos de doença diagnosticada. A maior média de LTCD4+ final foi em pessoas com tempo de doença de 8,1 a 18 anos, com 597,19 cel/mm³. No período de ≥ 18,1 anos de doença, foram detectados 11 pacientes com aumento de 31,53% de média entre os índices iniciais e finais dos LTCD4+ e com redução de 92,69% da carga viral. Os resultados de carga viral média para contagem <50 cópias/mL foi verificado para 121 pacientes nos últimos exames. As maiores taxas para os níveis médios de LTCD4+ iniciais <350 cel/mm3 foram verificadas em 71,46% dos pacientes, enquanto 50,54% tiveram índices finais >500 cel/mm3. Conclusão: Observou-se que os níveis de carga viral foram inversamente proporcionais aos LTCD4+, apresentando uma diminuição significativa para as contagens finais de carga viral, e um aumento expressivo para LTCD4+.
CARACTERIZAÇÃO DAS OCORRÊNCIAS DE ACIDENTES DE TRABALHO GRAVES
Authors: Guimarães Cardoso Mariana , Oliveira Romero Ligia , Carvalho Bachi Zeuma , Trefiglio Eid Vera Rolemberg , Beretta Denise , De Carvalho Jericó Marli
Published: January 2017

Introdução: Os acidentes de trabalho geram prejuízos em âmbitos social e econômico, podendo levar a ocorrência de sérios danos que comprometam a saúde física e psicológica do trabalhador, sua família e dependentes. Objetivo: Caracterizar as ocorrências de acidentes de trabalho grave na região noroeste do estado de São Paulo. Material e Métodos: Estudo descritivo, transversal de abordagem quantitativa acerca de acidentes de trabalho registrados no Sistema Nacional de Agravos de Notificação (SINAN) do Ministério da Saúde do banco do Grupo de Vigilância Epidemiológica (GVE) XXIX, no período de 2008 a 2013. Submetido ao Comitê de ética (parecer nº 501.897). Resultados: Notificados 4.687 casos de acidentes de trabalho grave na região de São José do Rio Preto. A maior parte dos acidentes notificados ocorreu com homens (80,2%), faixa etária de 25 a 45 anos (44,9%), nível médio de escolaridade 58,9%, tempo de trabalho de 1 a 5 anos, com registro em carteira de trabalho (82,1%). Os aciden-tes de trabalho típicos corresponderam a 65,8% e a maior parte dos atendimentos médicos prestados foi ambulatorial e evoluiu com alguma incapacidade temporária, total ou permanente (43,7%), no qual a parte do corpo mais atingida foram as mãos. As principais causas foram relacionadas com motos e a fratura como lesão em 49% dos casos. Conclusão: O mapeamento gerado por este estudo instrumentaliza os trabalhadores, contratantes e gestores na tomada de decisão e estratégias voltadas prevenção e promoção de agravos laborais.
Amniocentesis increases level of anxiety in women with invasive prenatal diagnosis of Down syndrome
Authors: Tursinawati Yanuarita , Thain Serene , Choi Christina , Seow George Heong Yeo
Published: January 2017

Backgound
Invasive prenatal diagnosis (PND) through amniocentesis and chorionic villus sampling (CVS) can detect Down syndrome. Pregnant women usually experience a variety of psychological responses associated with invasive PND. This study is intended to assess depression, anxiety and stress levels and the factors related to their psychological responses in pregnant women with invasive prenatal diagnosis of Down syndrome.

Methods
A cross sectional study was conducted at Kandang Kerbau Women’s and Children’s Hospital, Singapore. The psychological responses of 70 women undergoing PND were assessed by Depression Anxiety Stress Scale 21 (DASS 21) questionnaire. A multiple linear regression analysis was used to analyze association between knowledge and perceived risk with psychological responses (CI 95% and significance value p<0.05).

Results
More than half of the participants had normal anxiety (55.7%), stress (72.8%), depression levels (65.8%). The results revealed significantly higher level of anxiety in women with gestational age >13 weeks who had pursued amniocentesis. Women with no previous children had higher levels of depression and stress. Women who pursued amniocentesis had significantly higher anxiety scores compared to women undergoing CVS (p=0.015).

Conclusions
Women’s psychological responses are associated with gestational age, type of procedure and parity. The level of anxiety increased in women who underwent amniocentesis for diagnosis of Down syndrome. Knowledge and perceived risk of having a baby with Down syndrome do not seem to have psychological effects to women.
Central obesity increases the risk of type 2 diabetes mellitus among urban adults
Authors: Pradono Julianty , Kusumawardani Nunik , Delima Delima
Published: January 2017

Background
In Indonesia the number of persons with type 2 diabetes mellitus (T2DM) was 8.5 million in 2013, and is estimated to be 11.8 million in 2030. The aim of this study was to determine the major risk factors associated with T2DM prevalence in urban aged >15 years.

Methods
An observational study with cross-sectional design was used with the data from Riskesdas 2007 and 2013 on population aged >15 years. Total respondents were 294,352 (2007) and 368,281 (2013). Data were collected by trained personnel through interviews, blood pressure and anthropometry measurements, and blood glucose and lipid tests. Odds ratio (OR) was used to test the relationship between T2DM and a number of other variables. Multiple logistic regression analysis was obtained to determine the main risk factor associated with T2DM prevalence.

Results
Type 2 diabetes mellitus prevalence increased from 2.3% (2007) to 2.5% (2013). T2DM tended to be increased in the younger age groups. Low education, middle-to-high economic status, less physical activity, smoking >200 cigarettes, and high risk blood lipid levels were strongly associated with T2DM prevalence. The main risk factors were inadequate physical activity (2007: OR 1.9;95% CI:1.16–2.98 and 2013: OR 2.44;95% CI: 1.57-3.78) and central obesity (2007: OR 1.8;95% CI:0.99–3.10, and 2013:OR 3.84; 95% CI: 2.49-5.93) after controlling for age, gender, employment and economic status.

Conclusions
Type 2 diabetes mellitus prevalence in the population aged >15 years increased within 5 years. Lack of physical activity and central obesity were the major risk factors of T2DM prevalence in urban adults.
High MMP-9 and TNF-α expression increase in preterm premature rupture of membranes
Authors: Sulistyowati Sri , Zakia Yuniarsih , Khasan Soetrisno
Published: January 2017

Preterm delivery is one of the causes of high perinatal morbidity and mortality. Matrix metalloproteinase 9 (MMP-9) is important for extracellular matrix (ECM) remodeling and may cause preterm labor and premature rupture of membranes (PROM). Tumor necrosis factor-α (TNF-α) as a pro-inflammatory cytokine plays a role in stimulating uterine activity and cervical ripening by degrading the ECM of the amniotic membranes through MMP-9. This study aimed to determine differences between MMP-9 and TNF-α expression of the membranes in preterm delivery with premature rupture of membranes (PPROM) and without PROM.

Methods

An analytic observational study with cross-sectional approach was conducted in 24 subjects, who were divided into 2 groups, with 12 subjects in the preterm delivery group with PROM and 12 subjects in the preterm delivery group without PROM. The expression of MMP-9 and TNF-α in the amniotic membrane was determined by immunohistochemistry. Data were analyzed using the t test.

Results

MMP-9 expression in the amniotic membrane of preterm delivery subjects with PROM (8.6 ± 3.1%/field) differed significantly with that of preterm delivery subjects without PROM (5.5 ± 2.3 %/ field) (p=0.001). TNF-α expression in the amniotic membrane of preterm delivery subjects with PROM (8.0 ±3.0%/field) also differed significantly with that of preterm delivery subjects without PROM (3,3 ± 1.5%/field) (p=0.000).

Conclusion
Expression of MMP-9 and TNF-α was higher in the amniotic membrane of preterm delivery subjects with PROM than in preterm delivery subjects without PROM and can thus be used as predictor to avoid PPROM.
Inverse correlation between serum albumin and serum lactate in adults with dengue
Authors: Mauleti Ifael Yerosias , Suhendro Suhendro , Nainggolan Leonard , Rumende Martin
Published: January 2017

BACKGROUND
Dengue infection is an acute viral infection, in the natural history of which plasma leakage may occur, resulting in shock followed by tissue hypoxia, with death as the final outcome if not treated properly. The purpose of this study was to determine the correlation of the hematocrit, serum albumin concentration, and the presence of pleural effusion or ascites, with hyperlactatemia in adult dengue patients.

METHODS
A cross-sectional study was conducted on 62 subjects. The inclusion criteria were: diagnosed dengue viral infection, age >14 years, fever during three consecutive days, and hyperlactatemia. Serum albumin was measured on an Advia 1800 analyzer using the bromocresol green method. The lactate oxidase method was used to determine serum lactate levels. Pleural effusion and/or ascites was determined using an ultrasound scanner (Xario SSA-660 A, Toshiba, Japan). The Pearson correlation test was used to analyze the data.
 
RESULTS
There was no significant correlation between the hematocrit (r=0.11; p=0.301), serum albumin (r=0.003;p=0.981), and pleural effusion or ascites (r=0.75; p=0.692) with serum lactate levels. However, in patients aged >30 years there was a significant inverse correlation between serum albumin and lactate levels (r =- 0.663;p=0.026).

CONCLUSION
This study demonstrated a significant inverse correlation between albumin and serum lactate levels in dengue patients aged > 30 years. This can aid in the early recognition and prompt management of at-risk patients to reduce morbidity and mortality.
Musculoskeletal manifestations in type 2 diabetes mellitus
Authors: Deshmukh Deepti P. , Akarte Asmita G.
Published: January 2017

Background: Musculoskeletal complications of diabetes have been generally ignored and poorly treated as compared to other complications. Hence we carried out this study to find the prevalence of musculoskeletal manifestations in type II diabetes mellitus and its correlation with age, BMI, duration of diabetes, and control of diabetes.Methods: 100 consecutive patients of type II diabetes were studied. Duration of diabetes, control of diabetes, and any musculoskeletal complaints were noted. Complete examination with special reference to BMI, waist circumference and waist hip ratio was done. Fasting and postprandial blood sugar and HbA1c was estimated. Correlation of musculoskeletal manifestations with age, BMI, duration of diabetes, and control of diabetes was evaluated and statistical analysis was done.Results: Study shows that the prevalence of musculoskeletal manifestations was 42%. Difficulty with stairs (73 cases) and joint pain (87cases) were the commonest difficulties patients experienced. Most common affected joint was shoulder joint (56%). Adhesive capsulitis (28 cases), tendonitis (15 cases), limited joint mobility (3 cases) were commonest musculoskeletal manifestations. There was a statistically significant positive correlation between musculoskeletal  manifestations and age (odds ratio: 4.4), BMI (odds ratio: 9.6), and control of diabetes (odds ratio: 2.61). There was a positive correlation between duration of diabetes and the presence of musculoskeletal manifestations; however it was not statistically significant.Conclusions: Musculoskeletal manifestations are frequent in Type 2 diabetics and have a positive correlation with age, duration of diabetes, control of diabetes, and BMI.
An observational study on the incidence of HER-2/neu receptor over-expression and comparison of clinical presentation between HER-2/neu positive and HER-2/neu negative breast cancer
Authors: Chatterjee Sajib , Mukherjee Madan Mohan , Nath Nemai Chandra , Samanta Saugata , Saha Asis Kumar
Published: January 2017

Background:Tumours that over express HER2/neu are less responsive to chemotherapy and patients with these tumours have a reduced survival compared with patients with normal levels of HER2/neu. The aim was to determine the frequency of HER-2/neu receptor over-expression in Breast cancer patients and its comparison to Her-2/neu negative breast cancer in respect to clinical presentation, risk factors, clinical staging, pathological staging.Methods: 50 patients who presented with Invasive ductal carcinoma of breast, meeting inclusion and exclusion criteria were included in the study. They were divided into two groups; according to Her-2/neu receptor over-expression (Yes/No).Incidence of Her-2-neu receptor over-expression was determined among the sample population. Both groups were compared on the basis of various parameters.Results: Young age at presentation, negative hormone receptor status (ER/PR), high grade of tumour, large sized tumour and increased axillary lymph nodes are more common in Her-2/neu over-expression patients. These parameters are statistically significant.Conclusions: Her-2/neu overexpressing breast cancers have increased invasive and metastatic capability and are less responsive to chemotherapy. They have increased risk of recurrence and patients with these tumours have a reduced survival compared with patients with normal levels of HER2/neu.
A Support of Independent Processes Outside of Information System, Using an Ontology Driven Application
Authors: Burita Ladislav
Published: January 2017

The purpose of the article is to analyze support of the independent processes, using any tool of information technology (IT) outside of the information system (IS) in the enterprise environment. The useful tool of IT could be the software (SW) ATOM, an ontology-driven web based application. Changes in IS are very expensive, complicated and risky, but it should be suggested solution omitted. The extensive literature review of the current state of the topic is added. The chosen process is innovation; the life cycle of innovation is explained: suggestion of innovation, demand for the solution of innovation, the final solution of innovation, and project for implementation of innovation. The methodology of an ontology preparation for the SW application includes design scheme of classes and associations between classes, preparation table of assignment characteristics to classes, and implementation of an ontology design in SW ATOM. The real possibility to support independent processes outside of IS using an ontology-driven application was experimentally verified and confirmed, and the result of research work could be used for any process outside of IS. Limits of the proposed solution consist of only experimental laboratory verification. For the practical use, it should be necessary first to prepare a prototype for the corporation IS in an enterprise environment.
Perlindungan Perempuan Korban Kekerasan Perspektif Hukum Islam
Authors: Santoso Lukman , Arifin Bustanul
Published: January 2017

The issue of violence against wife physically and psychologically, today more frequent in the community. The factual reality shows that domestic violence against wife is a phenomenon that sometimes considered to be prevalent in society. The common assumption must not be separated from social construction in the society that the husband is the head of the family and has full authority to the family members, including his wife. In that context, this study attempts to analyze how the concept of the women protection as victims of domestic violence in Islamic law. In the context of the protection of women in the household, the texts of the Quran give many answers that require embodiment household with ma'ruf relationship in the sense of equal, fair and democratic. It is confirmed that Islamic law carries a mission ofprotection, which is a mercy for all human beings on earth. It also harmonized with applicable laws protecting women in Indonesia today.Persoalan kekerasan terhadap istri secara fisik maupun psikis, dewasa ini semakin sering terjadi di masyarakat. Realita tersebut secara faktual menunjukkan bahwa kekerasan dalam rumah tangga terhadap istri, merupakan suatu fenomena yang terkadang dianggap lazim di lingkungan masyarakat. Anggapan lazim ini tentunya tidak terlepas dari konstruksi sosial yang berkembang di tengah masyarakat bahwa suami adalah kepala keluarga dan memiliki otoritas penuh terhadap anggota keluarga termasuk isteri. Dalam konteks itu kajian ini berupaya mengupas tentang bagaimana konsep perlindungan terhadap perempuan korban KDRT dalam hukum Islam. Dalam konteks perlindungan perempuan dalam rumah tangga,teks-teks al-Qur’an memberikan banyak jawaban yang mengharuskan perwujudan hubungan rumah tangga secara ma’ruf dalam arti setara, adil dan demokratis. Hal ini menegaskan bahwa hukum Islam membawa misi perlindungan, yaitu sebagai rahmat bagi seluruh manusia di muka bumi. Hal ini juga diharmonisasikan dengan hukum perlindungan perempuan yang berlaku di Indonesia saat ini.
Spatial and Temporal Variation of Water Quality in the Bertam Catchment, Cameron Highlands, Malaysia
Authors: Rasul M.G. , Islam Mir Sujaul , Yunus Rosli Bin Mohd , Mokhtar Mazlin Bin , Alam Lubna , Yahaya F. M.
Published: January 2017

The spatio‐temporal variability of water quality associated with anthropogenic activities was studied for the Bertam River and its main tributaries within the Bertam Catchment, Cameron Highlands, Malaysia. A number of physico‐chemical parameters of collected samples were analyzed to evaluate their spatio‐temporal variability. Nonparametric statistical analysis showed significant temporal and spatial differences (p < 0.05) in most of the parameters across the catchment. Parameters except dissolved oxygen and chemical oxygen demand displayed higher values in rainy season. The higher concentration of total suspended solids was caused by massive soil erosion and sedimentation. Seasonal variations in contaminant concentrations are largely affected by precipitation and anthropogenic influences. Untreated domestic wastewater discharge as well as agricultural runoff significantly influenced the water quality. Poor agricultural practices and development activities at slope areas also affected the water quality within the catchment. The analytical results provided a basis for protection of river environments and ecological restoration in mountainous Bertam Catchment.
Humanistic Leadership, Organizational Culture and Corporate Citizenship Behaviour
Authors: Parameswar Naveen , Prasad Rajiv
Published: January 2017

Leadership plays a significant role in shaping an organization's culture. A new type of organization is
emerging that aims at not only earning profit through its business, but also at contributing to the benefit and
well being of the members of the society. These organizations are led by a new type of leader who is called a
humanistic leader (Prasad, 2011). This paper looks at the importance of humanistic leadership style in
shaping this new type of organization. We also look at these organizations using the lens of established
frameworks such as the Corporate Social Responsibility pyramid developed by Buchholtzand Carroll. These
organizations look at the well-being of all stakeholders including owners, vendors, customers, employees
and other shareholders. These organizations behave like responsible corporate citizens and new emerging
research suggests that these organizations are being rewarded by their customers, as well as the
shareholders. This development will in turn create a new model of business which is based on win-win
strategy for all the stakeholders of an organization. Many of these new class of leaders display higher order
needs such as self-transcendence and self-actualization in the Maslow's schema of needs arranged in a
hierarchical pyramid. This paper suggests that the research in the areas of individual motivation of leaders
can be merged with research in the area of leadership and organizational culture to help understand this
new emerging trend.
Фактори ризику переломів проксимального відділу стегнової кістки у хворих старших вікових груп
Authors: Grygorieva N.V. , Zubach O.B.
Published: January 2017

Актуальність. На сьогодні переломи проксимального відділу стегнової кістки (ПВСК) залишаються важливою медико-соціальною проблемою. Продовжується вивчення факторів ризику, оскільки доведено, що їх вплив істотно відрізняється в різних популяціях. Метою даного дослідження була оцінка факторів ризику в осіб старших вікових груп з переломами ПВСК. Матеріали і методи. Обстежено 122 особи віком 50 років і старше (88 жінок та 34 чоловіки з внутрішньо- та позасуглобовими переломами ПВСК). Оцінку факторів ризику остеопорозу та переломів проводили за допомогою анкетування (українська версія опитувальника FRAX®, доповнена авторами). Результати. У 79,4 % чоловіків і 73,9 % обстежених жінок встановлено клінічно діагностовані переломи в минулому. Найбільш часто у жінок були зареєстровані переломи кісток передпліччя (39,4 %), тіл хребців (25,8 %) і плечової кістки (12,1 %), у чоловіків — переломи плечової кістки та кісток гомілки (25 %), кісток передпліччя та переломи тіл хребців (17,9 %). Термін від попереднього перелому у 80,3 % обстежених жінок і 78,6 % чоловіків становив більше 5 років. У 52,3 % жінок і 50 % у чоловіків з переломами ПВСК підтверджено сімейний анамнез перелому стегнової кістки в близьких родичів (матері або батька). У 79,4 % чоловіків і 71,6 % обстежених жінок встановлено наявність переломів іншої локалізації у близьких родичів. До перелому ПВСК 85,3 % чоловіків і 52,1 % жінок мали показники 10-річної ймовірності перелому стегнової кістки (FRAX®) 3 і більше, що свідчить про необхідність їх оцінки для своєчасного лікування остеопорозу. Висновки. Вищезазначене слід враховувати для планування профілактичних заходів щодо остеопорозу та його ускладнень в осіб старших вікових груп.
Обсяг хірургічної допомоги пораненим із вогнепальними переломами кісток передпліччя на етапах медичної евакуації під час антитерористичної операції
Authors: Korol S.O. , Matviichuk B.V. , Domansky A.M.
Published: January 2017

Мета дослідження: визначити структуру операційних втручань, що виконані на етапах медичної евакуації (ЕМЕ) пораненим із вогнепальними переломами кісток передпліччя та відривами кінцівки під час антитерористичної операції (АТО) з 2014 по 2015 рік. Матеріали та методи. Масив клінічного дослідження становили 45 поранених із вогнепальними переломами кісток передпліччя та мінно-вибуховими пораненнями з 2014 по 2015 рік під час проведення антитерористичної операції. У структурі поранень передпліччя переломи та відриви становили 10,95 %. Bогнепальні переломи спостерігались у 88,89 % поранених, відриви кінцівки на рівні передпліччя — в 11,11 %. Усі поранені були чоловіками, 88,89 % — військовослужбовцями Збройних сил України. Результати та обговорення. У поранених із вогнепальними переломами кісток передпліччя та відривами кінцівки на ЕМЕ базового та першого рівнів допомоги проводили тимчасову зупинку кровотечі, накладали асептичну пов’язку, проводили знеболювання, іммобілізацію підручними засобами та термінову евакуацію. На ЕМЕ другого рівня допомоги виконували первинну хірургічну обробку рани (81,83 %) та фасціотомію (42,42 %). Важливим протишоковим заходом другого рівня було стабільне накладання стрижневого апарата зовнішньої фіксації (36,36%), а також внутрішньом’язове введення антибіотиків та правцевого анатоксину. На ЕМЕ третього та четвертого рівнів переважну більшість операційних втручань становили повторні хірургічні обробки ран та фасціотомії. Підвищенню якості виконання повторних хірургічних обробок сприяли використання вакуум-терапії й ультразвукової кавітації, а також медична реабілітація. Висновки. Надання допомоги пораненим із вогнепальними переломами та відривами кінцівки на рівні передпліччя під час АТО призвело до 64,45 % добрих і 24,44 % задовільних функціональних результатів через 1–2 роки після поранення.
Математичне моделювання остеосинтезу черезвертлюгових переломів типу А1 із застосуванням різних металевих фіксаторів
Authors: Kalashnikov A.V. , Malyk V.D. , Lazarev I.A. , Kalashnikov O.V.
Published: January 2017

Із метою визначення оптимального виду остеосинтезу при оперативному лікуванні черезвертлюгових переломів типу А1 проведено комп’ютерне моделювання напружень на металеві фіксатори (пластина DHS та PFN-стрижень). Визначено, що найбільш біомеханічно обґрунтованою при черезвертлюгових переломах типу А1 є модель PFN-стрижня у варіанті без застосування гвинтів для дистального блокування, про що свідчать мінімальне напруження на металевому фіксаторі та наявність оптимальної мікрорухливості між кістковими відламками. Проведене дослідження дозволить визначити диференційований підхід до лікування хворих із черезвертлюговими переломами стегнової кістки, покращить ефективність надання медичної допомоги цій категорії тяжких хворих.
Ефективність застосування препарату Гербіон сироп ісландського моху при лікуванні сухого кашлю в дітей
Authors: Niankovskyi S.L. , Yatsula M.S. , Babik I.V. , Yaskiv V.B. , Shpychka O.I. , Yandio B.V.
Published: January 2017

У статті розглянуті етіологічні та патогенетичні чинники виникнення сухого кашлю в дітей. Наведений власний досвід застосування препарату Гербіон сироп ісландського моху при лікуванні постінфекційного сухого кашлю в дітей віком 4–10 років. Застосування препарату істотно зменшує інтенсивність сухого кашлю, швидко припиняє нічні приступи кашлю, дозволяє покращити показники якості життя дітей. Препарат Гербіон сироп ісландського моху добре переноситься дітьми й не викликає побічних реакцій при застосуванні.
Синдром емоційного вигорання при викладанні дисципліни «Педіатрія» студентам старших курсів факультету підготовки іноземних громадян: розпізнавання симптомів та шляхи усунення
Authors: Lembryk I.S.
Published: January 2017

У статті наведені дані щодо дефініції, складових та основних проявів синдрому емоційного вигорання загалом та конкретно у викладачів-медиків. Автор проаналізувала історію питання за останні десятиліття, провела оцінку отриманих даних, систематизувала основні підходи до виявлення та купірування симптомів емоційного вигорання. Встановлено негативні особистісні риси як викладача, так і студента-медика, що сприяють розвитку емоційного вигорання у викладача. Автор пропонує шляхи розв’язання цієї проблеми у вищій медичній школі.
Міжнародний проект ЕSO-EAST в Україні: оптимізація та поліпшення якості допомоги пацієнтам з інсультом
Authors: Chistik T.
Published: January 2017

Надано огляд ключових доповідей, представлених на засіданні, організованому ESO та Українським науково-практичним товариством неврологів, психіатрів та наркологів, де був презентований стратегічний міжнародний проект Європейської організації інсульту (European Stroke Organization - ESO). Даний захід було проведено в рамках науково-практичної конференції з міжнародною участю «Когнітивні порушення при неврологічних, психічних і наркологічних захворюваннях», що відбулася 6 - 7 жовтня 2016 року в м.Ужгороді (Україна).
Значення куріння в розвитку псоріатичного артриту і псоріазу
Authors: Golovach I.Yu.
Published: January 2017

У статті наведені нові дані щодо зв’язку куріння з розвитком псоріазу та псоріатичного артриту. Встановлено, що куріння погіршує тяжкість перебігу та прогноз псоріазу, а також те, що пацієнти, які курять, є менш чутливими до терапії. Патогенетичні зв’язки вказують, що куріння індукує окисні ушкодження, сприяє запальним змінам, а також підвищує експресію генів, пов’язаних із псоріазом. Крім того, нікотин зв’язує ацетилхолінові рецептори на дендритних клітинах, макрофагах, ендотеліальних клітинах і кератиноцитах. Це призводить до запалення і Th1-імунної стимуляції клітин, а потім — до вираженої міграції лейкоцитів у шкіру внаслідок підвищеної експресії молекул міжклітинної адгезії‑1 і молекул судинної адгезії‑1 на ендотеліоцитах, до підвищеного ангіогенезу і безконтрольної проліферації кератиноцитів. Надано інформацію щодо генетичної схильності до розвитку псоріазу та артриту, а також ролі куріння в модифікації генетичних факторів. Куріння обумовлює своєрідну метаболічну і генетичну коморбідність при псоріазі та псоріатичному артриті, що визначає частоту загострень, тяжкість перебігу, а також розвиток ускладнень. У даний час лікарі можуть запобігти виникненню або загостренню пов’язаних із курінням хвороб, таких як, наприклад, псоріаз і псоріатичний артрит, стимулюючи своїх пацієнтів відмовитись від куріння.