bluuebunny/crossref_metadata_2025 huggingface dataset:
Advanced Glycation End Products (AGEs), Receptor for AGEs, Diabetes, and Bone: Review of the Literature
Authors: Asadipooya Kamyar , Uy Edilfavia Mae
Published: July 2019

Diabetes compromises bone cell metabolism and function, resulting in increased risk of fragility fracture. Advanced glycation end products (AGEs) interact with the receptor for AGEs (RAGE) and can make a meaningful contribution to bone cell metabolism and/or alter function. Searches in PubMed using the key words “advanced glycation end-product,” “RAGE,” “sRAGE,” “bone,” and “diabetes” were made to explain some of the clinical outcomes of diabetes in bone metabolism through the AGE–RAGE signaling pathway. All published clinical studies were included in tables. The AGE–RAGE signaling pathway participates in diabetic complications, including diabetic osteopathy. Some clinical results in diabetic patients, such as reduced bone density, suppressed bone turnover markers, and bone quality impairment, could be potentially due to AGE–RAGE signaling consequences. However, the AGE–RAGE signaling pathway has some helpful roles in the bone, including an increase in osteogenic function. Soluble RAGE (sRAGE), as a ligand decoy, may increase in either conditions of RAGE production or destruction, and then it cannot always reflect the AGE–RAGE signaling. Recombinant sRAGE can block the AGE–RAGE signaling pathway but is associated with some limitations, such as accessibility to AGEs, an increase in other RAGE ligands, and a long half-life (24 hours), which is associated with losing the beneficial effect of AGE/RAGE. As a result, sRAGE is not a helpful marker to assess activity of the RAGE signaling pathway. The recombinant sRAGE cannot be translated into clinical practice due to its limitations.
DrosophilaMon1 constitutes a novel node in the brain-gonad axis that is essential for female germline maturation
Authors: Dhiman Neena , Shweta Kumari , Tendulkar Shweta , Deshpande Girish , Ratnaparkhi Girish S. , Ratnaparkhi Anuradha
Published: July 2019

Monensin-sensitive 1 (Mon1) is an endocytic regulator that participates in the conversion of Rab5-positive early endosomes to Rab7-positive late endosomes. In Drosophila, loss of mon1 leads to sterility as the mon1 mutant females have extremely small ovaries with complete absence of late stage egg chambers – a phenotype reminiscent of mutations in the insulin pathway genes. Here, we show that expression of many Drosophila insulin-like peptides (ILPs) is reduced in mon1 mutants and feeding mon1 adults an insulin-rich diet can rescue the ovarian defects. Surprisingly, however, mon1 functions in the tyramine/octopaminergic neurons (OPNs) and not in the ovaries or the insulin-producing cells (IPCs). Consistently, knockdown of mon1 in only the OPNs is sufficient to mimic the ovarian phenotype, while expression of the gene in the OPNs alone can ‘rescue’ the mutant defect. Last, we have identified ilp3 and ilp5 as critical targets of mon1. This study thus identifies mon1 as a novel molecular player in the brain-gonad axis and underscores the significance of inter-organ systemic communication during development.
CXCL2 attenuates osteoblast differentiation by inhibiting the ERK1/2 signaling pathway
Authors: Yang Yang , Zhou Xinying , Li Yuejun , Chen Ajuan , Liang Wenquan , Liang Guojun , Huang Bin , Li Qingchu , Jin Dadi
Published: July 2019

The C-X-C motif chemokine ligand 2 (CXCL2), a member of the CXC receptor ligand family, is involved in various immune and inflammatory processes, but its effect(s) on bone formation have not yet been reported. We report here that CXCL2 is enriched in bone marrow and show abundant expression of CXCL2 in osteoblasts of osteoporotic mice. CXCL2 neutralization within the bone marrow by using antibody alleviated bone loss in mice, indicating a negative role of CXCL2 in bone formation. In line with this, CXCL2 overexpression attenuated proliferation, as well as differentiation, of osteoblasts in vitro. By contrast, CXCL2 downregulation promoted osteoblast expansion and differentiation. Mechanistically, CXCL2 inhibits the ERK1/2 (MAPK3/1) signaling pathway in osteoblasts. Activation of ERK1/2 abolishes the inhibitory effect of CXCL2 in osteoblasts, whereas inactivation of ERK1/2 reverses the osteogenic role of CXCL2 inhibition. These results show that CXCL2 attenuates osteoblast differentiation through inhibition of the ERK1/2 signaling pathway. We demonstrate here that CXCL2 is a negative regulator of bone formation and clarify the responsible mechanisms. Therefore, pharmaceutical coordination of CXCL2 and of the pathways through which it is regulated in osteoblasts might be beneficial regarding bone formation.
Fatiguing stimulation increases curvature of the force-velocity relation in isolated fast-twitch and slow-twitch rat muscles
Authors: Kristensen A. M. , Nielsen O. B. , Pedersen T. H. , Overgaard K.
Published: July 2019

In skeletal muscles the ability to generate power is reduced during fatigue. Maximal power can in isolated muscles be calculated from the force-velocity relationship. This relationship is well described by the Hill equation, which contains three parameters: 1) Maximal isometric force, 2) maximum contraction velocity, and 3) curvature. Here, we investigated the hypothesis that a fatigue-induced loss of power will be associated with changes in curvature of the force-velocity curve in slow-twitch muscles but not in fast-twitch muscles during the development of fatigue. Isolated rat soleus (slow-twitch) and EDL (fast-twitch) muscles were incubated in Krebs-Ringer solution at 30°C and stimulated electrically at 60 Hz (soleus) and 150 Hz (EDL) to perform a series of concentric contractions to fatigue. Force-velocity data were fitted to the Hill equation, and curvature was determined as the ratio of the curve parameters a/F0 (inversely related to curvature). At the end of the fatiguing protocol, maximal power decreased by 58±5% (soleus) and 69±4% (EDL) compared to initial values in non-fatigued muscles. At the end of the fatiguing sequence, curvature increased as judged from the decrease in a/F0 by 81±20% in soleus and by 31±12% in EDL. However, during the initial phases of fatiguing stimulation we observed a small decrease in curvature in EDL muscles, but not soleus, which may be a result of post-activation potentiation. In conclusion, fatigue-induced loss of power is strongly associated with an increased curvature of the force-velocity relationship, particularly in slow-twitch muscles.
УCТРAНEНИE ДEФEКТOВ CВOДA ЧEРEПA C ПРИМEНEНИEМ МAТEРИAЛOВ C ПAМЯТЬЮ ФOРМЫ
Authors: Radkevich Andrey Anatolevich , Kasparov Eduard Vilyamovich , Mamedov Rasim Khaligovich , Sinyuk Ilya Vasilevich
Published: July 2019

Цeль. Пoвышeниe эффeктивнocти хирургичecкoгo уcтрaнeния дeфeктoв кocтeй мoзгoвoгo чeрeпa путeм рaзрaбoтки нoвых мeдицинcких тeхнoлoгий c иcпoльзoвaниeм мaтeриaлoв c пaмятью фoрмы.Мaтeриaлы и мeтoды. Выпoлнeнo oпeрaтивнoe уcтрaнeниe изъянoв cвoдa чeрeпa у 20 бoльных в вoзрacтe oт 17 дo 65 лeт. Рaзмeры дeфeктoв cocтaвляли пo плoщaди oт 30 дo 60 cм2. Иcпoльзoвaли тoнкoпрoфильныe ceтчaтыe имплaнтaты нa ocнoвe никeлидa титaнa. В кaчecтвe рeбрa жecткocти примeняли плacтинчaтыe имплaнтaты из никeлидa титaнa c прoницaeмoй пoриcтocтью.Рeзультaты. Вo вceх cлучaях пoлучeны удoвлeтвoритeльныe кocмe­ти­чecкиe и функциoнaльныe рeзультaты. Рeнтгeнoлoгичecки диaгнocти­рoвaлocь пoлнoцeннoe вoccтaнoвлeниe фoрмы чeрeпнoй кoрoбки.Зaключeниe. Тoнкoпрoфильный ceтчaтый никeлид титaнa c выcoкoй эффeктивнocтью мoжeт быть иcпoльзoвaн для зaмeщeния кocтных дeфeктoв cвoдa чeрeпa любых oбъeмoв, кoнфигурaции и лoкaлизaции.
СОСТОЯНИЕ СИСТЕМЫ ГЕМОСТАЗА У БОЛЬНЫХ АДЕНОМОЙ И РАКОМ ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫ
Authors: Alymova Ekaterina Victorovna , Smirnova Olga Valentinovna , Kasparov Eduard Vil’yamovich , Titova Nadezhda Mitrofanovna
Published: July 2019

Обследовано 161 мужчина в возрасте от 45 до 83 лет с различной стадией заболевания. Среди обследованных выделены три группы: больных аденомой простаты – 46 пациентов, группа больных раком предстательной железы – 53 пациента, группа сравнения – 48 относительно здоровых мужчин той же возрастной категории. Всем обследованным проводилось биохимическое исследование крови с определением компонентов системы гемостаза, характеризующих все звенья свертывающей системы крови: АЧТВ, ПТВ, МНО, фибриноген. Цель исследования – выявить особенности системы гемостаза у больных аденомой и раком простаты.
СОСТОЯНИЕ ГЕМОСТАЗА У БОЛЬНЫХ С РАЗНОЙ ЧУВСТВИТЕЛЬНОСТЬЮ К АЦЕТИЛСАЛИЦИЛОВОЙ КИСЛОТЕ ПРИ ИШЕМИЧЕСКОЙ БОЛЕЗНИ СЕРДЦА
Authors: Goncharov Maxim Dmitrievich , Vеselov Andrey Evgenievich , Pats Yury Stepanovich
Published: July 2019

С целью изучения гемостаза у чувствительных и резистентных к ацетилсалициловой кислоте (АСК) больных ишемической болезнью сердца (ИБС) обследовано 53 пациента с ИБС. Больные разделены на группы чувствительных и резистентных к АСК. У всех обследованных изучались показатели сосудисто-тромбоцитарного гемостаза. Установлено, что у резистентных к АСК больных повышена АДФ-индуцированная агрегационная способность тромбоцитов, снижено их количество и повышен уровень фактора Виллебранда.
СОСТОЯНИЕ ГЛУТАТИОНОВОГО ЗВЕНА АНТИОКСИДАНТНОЙ ЗАЩИТЫ БОЛЬНЫХ МЕХАНИЧЕСКОЙ ЖЕЛТУХОЙ ЖЕЛЧНОКАМЕННОГО ГЕНЕЗА
Authors: Elmanova Nina Georgievna , Smirnova Olga Valentinovna
Published: July 2019

Было изучено состояние глутатионового звена антиоксидантной защиты у больных механической желтухой желчнокаменного генеза. Выявлен высокий уровень окислительного стресса и высокая активность глутатион зависимых ферментов.
ИЗМЕНЕНИЯ ИММУНОЛОГИЧЕСКИХ ПОКАЗАТЕЛЕЙ У БОЛЬНЫХ ХРОНИЧЕСКИМ ОПИСТОРХОЗОМ С КЛИНИКОЙ ПОРАЖЕНИЯ ГЕПАТОБИЛИАРНОЙ СИСТЕМЫ
Authors: Moskalenko Olga Leonidovna , Filimonova Lyudmila Anatolevna , Yaskevich Roman Anatolyevich
Published: July 2019

У больных хроническим описторхозом с клиникой поражения органов гепатобилиарной системы выявлены существенные изменения иммунологических показателей клеточного и гуморального звена иммунитета с увеличением цитотоксических лимфоцитов, снижении ИРИ и фагоцитарной активности клеток крови, в сравнении с пациентами, у которых хронический описторхоз протекал бессимптомно.
Sociodemographic and clinical profile of patients with dual diagnosis living in Warsaw district Mokotow in comparison with participants in other European countries- results of the international, multicentre research project ISADORA.
Authors: Charzyńska Katarzyna , Sawicka Maryla , Osuchowska- Kościjańska Anna , Chądzyńska Małgorzata , Giguere Marta , Kasperek- Zimowska Beata , Bronowski Paweł
Published: July 2019

Cel

Celem obecnego badania było porównanie profilu społeczno- demograficznego i klinicznego pacjentów z podwójną diagnozą leczonych w Warszawie z profilem pacjentów leczonych w innych ośrodkach w Europie.

Metoda

Do badania w Warszawie zakwalifikowano 50 kolejno przyjmowanych pacjentów, w całym programie badawczym uczestniczyło 352 pacjentów z 7 ośrodków w Europie. Rekrutacja odbywała się na całodobowych oddziałach ogólnopsychiatrycznych oraz całodobowych oddziałach leczenia podwójnych diagnoz. Dane zostały zebrane w trakcie jednorazowego wywiadu przy wykorzystaniu kwestionariuszy M.I.N.I i EuropAsi.

Wyniki

Zarówno w Warszawie, jak i w całej badanej populacji mężczyźni stanowili blisko 2/3 grupy. Pacjenci badani w Warszawie częściej mieszkali z bliskimi i pozostawali w trwałych związkach niż badani w innych ośrodkach. Zaburzenia depresyjne były najczęstszą diagnozą w grupie pacjentów leczonych w Warszawie i były rozpoznawane istotnie częściej, niż miało to miejsce w Tampere. Ponadto w tej grupie istotnie rzadziej, w porównaniu do pacjentów badanych w pozostałych ośrodkach, rozpoznawano nadużywanie przetworów konopi, a istotnie częściej- nadużywanie leków uspokajających.

Wnioski

Różnice między ośrodkami dotyczące profilów społeczno- demograficznych i klinicznych pacjentów z podwójną diagnozą wynikały zarówno z uwarunkowań społeczno- kulturowych (np. dostępność substancji), jak i przyjętej metodologii badania.
Effectiveness of ketamine in depressed patients resistant to ECT or rTMS therapy.
Authors: Gosek Paweł , Chojnacka Magdalena , Święcicki Łukasz , Bieńkowski Przemysław
Published: July 2019

Cel

W ostatnich latach opublikowano wiele opisów dotyczących możliwości uzyskania szybkiej i istotnej klinicznie poprawy stanu psychicznego u pacjentów z rozpoznaniem depresji po podaniu antagonisty receptorów N-metylo-D-asparaginowych (NMDA) - ketaminy. Większość badań dotyczy podania ketaminy pacjentom z depresją lekooporną, co jednak nie oznaczało oporności na leczenie elektrowstrząsowe. W niniejszej pracy prezentujemy serię 5 przypadków pacjentów opornych na różne metody leczenia biologicznego (w tym leczenie farmakologiczne, EW, rTMS) u których w warunkach naturalistycznych zastosowano ketaminę w subanestetycznej dawce 0,5 mg/kg. Zgodnie z wiedzą autorów tej pracy jest to pierwszy opisany przypadek leczenia ketaminą u pacjenta z depresją oporną na leczenie farmakologiczne i rTMS.

Metoda

W opisanej grupie u dwóch pacjentów rozpoznano depresję nawracającą, u jednego chorobę afektywną dwubiegunową, u dwóch kolejnych ciężki epizod depresji. Skuteczność i możliwe działania niepożądane monitorowano przy użyciu skal psychometrycznych, podobnie podstawowe parametry życiowe oraz zapis EKG w czasie wlewów ketaminy.

Wyniki

W opisywanej grupie obserwowano przejściową poprawą stanu psychicznego, lecz efektywność leczenia była istotnie mniejsza niż wynikałoby to z dotychczasowych doniesień. Obserwowano dobrą tolerancję, przejściowe wahania ciśnienia tętniczego oraz przejściowe występowanie łagodnych objawów dysocjacyjnych. Nie w pełni satysfakcjonujące wyniki kuracji ketaminą mogą być związane z opornością na wcześniejsze próby leczenia biologicznego, współwystępowaniem objawów lęku i somatyzacji, lub heterogennością opisywanej grupy.

Wnioski

Prezentowane wyniki nie przemawiają za stosowaniem ketaminy w monoterapii w grupie pacjentów z depresją oporną na leczenie biologiczne
Taking care of the sick Veteran – Mental health care within the Department of Veterans Affairs, USA
Authors: Klasa Katarzyna , Gędzior Joanna , DePry D.R.
Published: July 2019

W artykule przedstawiono sposób funkcjonowania systemu psychiatrycznej opieki zdrowotnej dla weteranów w USA na przykładzie stanu Kalifornia. Przedstawione zostały także dwa opisy przypadków klinicznych ilustrujące problematykę zaburzeń zdrowia psychicznego tej populacji pacjentów. Weterani, jak również żołnierze służby czynnej oraz cywilni pracownicy wojska stanowią grupę pacjentów zmagających się z zaburzeniami zdrowia psychicznego, wymagającą rosnącej uwagi klinicystów nie tylko w USA, ale wszystkich krajach, które zaangażowane są w misje wojskowe/pokojowe.
W artykule przedstawiono sposób funkcjonowania systemu psychiatrycznej opieki zdrowotnej dla weteranów w USA na przykładzie stanu Kalifornia. Przedstawione zostały także dwa opisy przypadków klinicznych ilustrujące problematykę zaburzeń zdrowia psychicznego tej populacji pacjentów. Weterani, jak również żołnierze służby czynnej oraz cywilni pracownicy wojska stanowią grupę pacjentów zmagających się z zaburzeniami zdrowia psychicznego, wymagającą rosnącej uwagi klinicystów nie tylko w USA, ale wszystkich krajach, które zaangażowane są w misje wojskowe/pokojowe.

W artykule przedstawiono sposób funkcjonowania systemu psychiatrycznej opieki zdrowotnej dla weteranów w USA na przykładzie stanu Kalifornia. Przedstawione zostały także dwa opisy przypadków klinicznych ilustrujące problematykę zaburzeń zdrowia psychicznego tej populacji pacjentów. Weterani, jak również żołnierze służby czynnej oraz cywilni pracownicy wojska stanowią grupę pacjentów zmagających się z zaburzeniami zdrowia psychicznego, wymagającą rosnącej uwagi klinicystów nie tylko w USA, ale wszystkich krajach, które zaangażowane są w misje wojskowe/pokojowe.
­A Defense of Analogy Inference as Sui generis
Authors: Juthe André
Published: July 2019

Accounts of analogical inference are usually categorized into four broad groups: abductive, deductive, inductive and sui generis. The purpose of this paper is to defend a sui generis model of analogical inference. It focuses on the sui generis account, as developed by Juthe [2005, 2009, 2015, 2016] and Botting’s [2017] criticism of it. This paper uses the pragmadialectical theory of argumentation as the methodological framework for analyzing and reconstructing argumentation. The paper has two main points. First, that Juthe’s arguments against a deductive interpretation of prima facie analogy argumentation remain unaffected by Botting’s criticism, which means that many of the reasons against deductive reformulation of analogy argumentation still stand. The additional argument, which Botting himself brings up, that a deductive interpretation cannot account for the cumulative effect of analogies, just provides further reason to reject deductivism. The second main point of this paper is that an inductive interpretation of analogical inference also fails. There are constitutional differences between inductive and analogical inference that cannot be bridged. The result is a firm defense of the sui generis view of analogical inference.
Angiotensin receptor blockers as an alternative to angiotensin converting enzyme inhibitors
Authors: O'Donovan Kate
Published: July 2019

Cardiovascular disease is the leading cause of mortality in the UK with ischaemic heart disease and heart failure being the main contributors. The renin-angiotensin aldosterone system has an essential role in cardiovascular pathophysiology by increasing preload, afterload and left ventricular workload. Angiotensin converting enzyme inhibitor therapy is a first-line therapy in this patient population except for those who are intolerant of angiotensin converting enzyme inhibitors. Angiotensin receptor blockers are deemed as a safe alternative while achieving the same clinical benefit. Common adverse effects are hypovolaemia, hyperkalemia and renal dysfunction. The nursing role involves cardiovascular assessment, monitoring for adverse effects and patient education.
Depression in heart failure
Authors: Sharp John , McCowat Monica
Published: July 2019

Heart failure is one of the most prevalent long-term physical health conditions. It is suggested that up to 26 million people are living with it worldwide including approximately 920 000 people in the UK. Evidence has consistently demonstrated the links between cardiac health and mental health; therefore, this article will explain depression and its presentation in heart failure, as these two conditions have been strongly and consistently linked. The prevalence of depression in heart failure will be reviewed from epidemiological studies and an overview of the impact of comorbid depression in heart failure will be provided, with a particular focus on mortality, morbidity and quality of life outcomes. The relationship between depression and heart failure will be discussed by examining pathophysiological and behavioural mechanisms, as well as evidence regarding the appropriate identification and subsequent management of heart failure depression will be reviewed.
Apraclonidine in the unlicensed treatment of eyelid ptosis
Authors: Fromage Gemma
Published: July 2019

Eyelid ptosis is a complication that may occur following injection of botulinum toxin type A. It generally presents within 3–7 days of treatment. A drooping or lowering of the eyelid may be severe to the point that it leads to restriction of vision, or it may be subtle, with just the feeling of a heavy lid or, more typically, difficulty in being able to apply eye make-up. There is currently no licensed treatment for eyelid ptosis. Apraclonidine hydrochloride, commonly known as Iopidine is an alpha-adrenergic receptor agonist and causes the contraction of the Muller's muscle, which may result in an eyelid lift of 1–3 mm. There are factors that may lead to an increased risk of this complication, and there are also ways in which to help prevent it from occurring. Thorough consultations should always be given and practitioners should always ensure that they have in-depth knowledge of facial anatomy and musculature and use good injection technique.
VAT: implications for aesthetic practitioners
Authors: Collier Helena
Published: July 2019

The issue of VAT in medical aesthetics can be confusing. In this article, Helena Collier discusses the criteria to determine in which instances VAT is applicable to aesthetic services, and how this might change should the sector become demedicalised
Collaboration in aesthetics
Authors: Hubbard Kevin
Published: July 2019

Following on from his presentation at the Journal of Aesthetic Nursing's 2019 conference, Kevin Hubbard explores the idea of collaboration in aesthetics, discussing how his team use social media and training opportunities to connect with others
Methods of applying traction to unerupted maxillary incisors and safety considerations
Authors: Parker Kate , Acharya Priti , Collins Joanne M
Published: July 2019

Unerupted maxillary incisors should be identified and managed promptly. When exposure and bonding of a gold chain to an unerupted tooth is indicated, there are multiple methods that can be used to apply traction to the tooth. This paper outlines the different methods available, their advantages and disadvantages and the important safety considerations. Treatment often utilizes small components which may pose an inhalation or ingestion risk if not used appropriately.

CPD/Clinical Relevance: This article reviews the different methods available to align impacted upper incisors. It details the advantages and disadvantages of each method and highlights the associated safety considerations.
Nasal considerations with the Le Fort I osteotomy
Authors: McSwiney Timothy , Khan Sadaf , Dhariwal Daljit
Published: July 2019

Orthognathic surgery involves the correction of severe dentofacial deformities through a combination of orthodontics, surgery and, occasionally, restorative dentistry. This procedure, when involving surgical movement of the maxilla, can lead to changes in the overlying nasal morphology. In this paper, the standard nasal assessment that is undertaken prior to a Le Fort I osteotomy is outlined along with the reported nasal changes seen following this procedure. In addition, the various risk factors associated with adverse nasal changes are considered, as are the management techniques adopted by clinicians to minimize these changes

CPD/Clinical Relevance: Clinicians should be aware of the adverse nasal changes associated with the Le Fort I osteotomy.
DESAFIOS E OBSTÁCULOS PARA A CONSOLIDAÇÃO DE UM ECOSSISTEMA DE EMPREENDEDORISMO NA CIDADE DO RIO DE JANEIRO: UMA ANÁLISE COM BASE NA VISÃO DOS PRINCIPAIS PLAYERS
Authors: Santos Guilherme de Oliveira , Peixoto Fabio Vieira Pereira Cendão
Published: July 2019

Este artigo tem como objetivo investigar os desafios e obstáculos para a consolidação de um Ecossistema de Empreendedorismo no Rio de Janeiro. Para tanto, em primeiro lugar foi feita uma revisão bibliográfica sobre Ecossistemas de Empreendedorismo, bem como uma contextualização do cenário atual com base em dados secundários. Em seguida, foram realizadas entrevistas – por e-mail – com diferentes atores que compõem o Ecossistema de Empreendedorismo do Rio de Janeiro. As respostas foram analisadas por meio da técnica de Análise de Conteúdo, a partir das categorias definidas. Os resultados apontam que o Ecossistema de Empreendedorismo do Rio de Janeiro ainda é pouco desenvolvido, apesar de ter grande potencial de crescimento. Os principais obstáculos e desafios identificados são: o excesso de burocracia; a reduzida disponibilidade de capital; a falta de articulação entre os atores; a realização periódica de eventos para empreendedores e a criação de espaços compartilhados; e um maior estímulo a investimentos de impacto.
O USO DE TECNOLOGIAS COMO ESTRATÉGIA NA CONSTRUÇÃO DE CIDADES MAIS INTELIGENTES E SUSTENTÁVEIS
Authors: Saraiva Paola Pol , Camara Inara Pagnussat , Ribeiro Lauro André , Silva Thaísa Leal da
Published: July 2019

Nas últimas décadas, é possível verificar uma intensa migração da população mundial de áreas rurais para urbanas, gerando congregações de pessoas e diversas dificuldades relacionadas à gestão das cidades. Assim, os grandes centros urbanos apresentam inúmeros problemas relativos à gestão de resíduos e energia, escassez de recursos, poluição do ar, problemas de saúde humana e congestionamentos. Para mitigar estes problemas, uma alternativa é o desenvolvimento e utilização de tecnologias com foco na sustentabilidade. Assim, o presente artigo tem por objetivo identificar e analisar estratégias que contribuam para que as cidades tornem-se inteligentes através da utilização de Tecnologias de Informação e Comunicação (TICs), visando uma melhoria na sustentabilidade. Os resultados demonstram que a implantação de tecnologias nas cidades pode contribuir com questões relacionadas ao monitoramento e gerenciamento de serviços e infraestruturas, facilitando a gestão das cidades e garantindo o aumento da qualidade de vida da população.
ORIENTACIÓN EMPRENDEDORA, ORIENTACIÓN AL MERCADO Y CAPACIDADES DINÁMICAS EN PEQUEÑAS Y MEDIANAS EMPRESAS
Authors: Pastor Pérez María del Pilar , Rodríguez Gutiérrez Paola Isabel , Balbinot Zandra
Published: July 2019

Las capacidades que se desarrollan y su interacción son claves para comprender el desempeño de las organizaciones, especialmente en contextos dinámicos, en los que sostener ventajas competitivas es complicado. A partir de esta afirmación habitual en la literatura sobre el tema, el objetivo de este trabajo es analizar la relación entre la orientación al mercado, la orientación emprendedora, y las capacidades dinámicas en pequeñas y medianas empresas que operan en el mercado latinoamericano. El enfoque es cuantitativo, con diseño no experimental transeccional, y alcance exploratorio. El método consiste en un muestreo aleatorio de 330 empresas que respondieron un cuestionario para encuesta. Los datos se analizan mediante la estadística descriptiva y la correlación de variables. Entre los principales resultados destaca que el entorno no es evaluado como dinámico por los empresarios, y que existe relación entre las variables estudiadas: orientación emprendedora, orientación al mercado, capacidades dinámicas y desempeño.
ADOÇÃO DA AGRICULTURA DE PRECISÃO NA AMÉRICA DO SUL: O ESTADO DA ARTE EM ARGENTINA, BRASIL E COLÔMBIA
Authors: Pamplona João Batista , Rodrigues Silva Miguel Augusto
Published: July 2019

A América do Sul faz grande contribuição relativa à produção agrícola mundial. O crescimento extensivo da atividade agrícola na região aproxima-se do limite, restando à modalidade intensiva o potencial de superar desafios como sustentabilidade e competitividade, capaz ainda de produzir desenvolvimento econômico. As inovações são essenciais nesse sentido, especialmente as associadas à agricultura de precisão (AP), entendida como um conjunto de inovações organizacionais e de processo que conjuga mecanização com tecnologias de informação e comunicação (TIC), permitindo singularização da unidade de produção agrícola, ao se valer da variabilidade espacial e temporal em áreas de pequena escala. O objetivo deste artigo é analisar o “estado da arte” da adoção da AP na América do Sul, a partir do levantamento e da análise da produção acadêmica sobre o tema. Esta pesquisa de natureza exploratória enfoca a experiência de três países representativos das condições econômicas e edafoclimáticas da Região: Argentina, Brasil e Colômbia.
EVALUACIÓN DE LA ESCALA BRASILEÑA “GRADO DE INNOVATIVIDAD” EN PYMES PERUANAS
Authors: Sosa-Sacio Manuel , Matos-Reyes Nancy
Published: July 2019

Las teorías y modelos de innovación tradicionalmente han respondido a la realidad de empresas grandes y de países más desarrollados, pero en su evolución histórica se ha puesto en relieve la necesidad de estudiarla también en países emergentes y PYMEs, ya que enfrentan diferentes retos. Uno de los modelos de innovación vigentes que se enfoca en estos retos es el de la triple hélice (programas del gobierno que integran esfuerzos universidad-empresa), y dentro del contexto de dos proyectos de triple hélice (uno en Brasil y otro en Perú) se ha diseñado y evaluado una escala de grado innovatividad en estos países. Los resultados muestran que la escala es consistente en ambos países, aunque discriminando perfiles particulares. Se comprueba el ajuste teórico y empírico de la escala, pues predice el desempeño creativo y es afectado por la actitud innovadora del líder, tal como se planteó en el diseño.
Editorial V.35, n.105 (2019) - Edição Especial
Authors: G&R Editoria
Published: July 2019

Editorial V.35, n.105 (2019) - Edição Especial
Seismic Wave Propagation Simulation in a Poro-elastic Medium Using Spectral Method Elements in MPI-GPU Cluster: Study Case of Anticline Reservoir Trap
Authors: Sudarmaji Sudarmaji , Rudianto Indra , Rahmareza Muhammad Kautsar , Alfontius Yosua
Published: July 2019

Modeling 2D seismic wave propagation using spectral element method on MPI-GPU clusters has been implemented and can complete the problem of elastic-poro elastic medium model. Free surface boundary conditions and absorption layer will use the CPML method. Seismic wave propagation simulation in hybrid elastic-poroelastic medium has been carried out on hydrocarbon reservoir models with anticline type. In reservoir rocks that have a poro elastic medium, there will be a fast and slow P wave. While in non-reservoir rocks that have elastic medium, only P fast waves is observed. The computation time for an anticline type reservoir model with dimensions of 1 km x 1.5 km using MPI 4 nodes cluster with 48 CPU cores is 3 minutes 48 second.
The Appomattox Field: Norphlet Aeolian Sand Dune Reservoirs in the Deep-Water Gulf of Mexico
Authors: Godo Ted
Published: July 2019

Exploration for oil in the Norphlet reservoir in the deep-water Gulf of Mexico began in 2003 at prospect Shiloh (DC269). The well found oil but not an economic volume. The second prospect, Vicksburg (DC353), was drilled in 2007. This well found a larger in-place volume of oil, but with an immovable solid hydrocarbon component within pore spaces, there was great uncertainty as to the potential producible volumes. Two subsequent wells (Fredericksburg [DC486] and Antietam [DC268]) were dry and had a very small amount of oil, respectively. Finally, in late 2009, the fifth well (Appomattox [MC392]) was a significant discovery of high-quality oil in a thick aeolian Norphlet sandstone.
Perla Field: The Largest Discovery Ever in Latin America
Authors: Castillo Veronica , Benkovics Laszlo , Cobos Carlos , Demuro Daniel , Franco Alejandro
Published: July 2019

Perla gas field is a world-class giant and one of the most significant in Latin America in the last decade. The field was discovered in August 2009. It is the largest gas field in Latin America with approximately 17 trillion cubic feet (tcf) of gas in place, or 3.1 BBOE. The field, located in the shallow waters of the Gulf of Venezuela, was discovered, and is operated by Cardon IV S.A., a 50/50 joint operating company formed by Repsol and Eni.

The Perla discovery is important because it is a Play opener for the southern Caribbean domain, triggering a new exploration cycle in the region and proving a previously unknown Tertiary thermogenic petroleum system. The discovery well encountered a thick carbonate section (240 m [787 ft] thick) with excellent primary reservoir properties. The trap is a combination structural and stratigraphic, defined by a northwest–southeast trending asymmetric faulted structure and pinch-out of the carbonate reservoir rock to the north. The proven hydrocarbon column exceeds 350 m (1148 ft) and is in complete hydraulic continuity, and the structural-stratigraphic closure exceeds 100 km2 (39 mi2).
Breaking Barriers and Paradigms in Presalt Exploration: The Pão de Açúcar Discovery (Offshore Brazil)
Authors: de Luca Pedro Henrique Vieira , Matias Hugo , Carballo José , Sineva Diana , Pimentel Gustavo Antunes , Tritlla Jordi , Esteban Mateu , Loma Rubén , Alonso José Luis Algibez , Jiménez Ricardo Perona , Pontet Matthieu , Martinez Pedro Bonillo , Vega Victor
Published: July 2019

Pão de Açúcar is certainly one of the most impressive and challenging hydrocarbon accumulations found in the prolific Campos Basin, offshore Brazil. This discovery opened a new frontier for exploration in Brazil’s ultradeep waters, in depths ranging from 2500 to 2900 m (8202 to 9514 ft). Pão de Açúcar is the third discovery made by a consortium integrated by Repsol Sinopec Brasil (operator), Statoil do Brasil, and Petrobras in the Concession BM-C-33, with estimated resources of 700 million bbl of light oil and 3 tcf of gas. This discovery is the result of the integrated work of a multidisciplinary international team using some of the most advanced technologies available today in the oil exploration industry in seismic imaging, drilling, formation evaluation, and fluid-rock sampling analysis. This discovery consists of a significant hydrocarbon column hosted within a unique reservoir made up of a variety of basic volcanic rocks overlain by pervasively silicified microbial carbonate platform/ramps, grading toward profundal lake facies. This chapter summarizes the main results of the exploration and ongoing appraisal work regarding this unique hydrocarbon accumulation, highlighting both the complexity of the discovered reservoirs and the operational and technical challenges faced, and still to overcome, before beginning production.
The Jubilee Field, Ghana: Opening the Late Cretaceous Play in the West African Transform Margin
Authors: Dailly Paul , Henderson Tracey , Kanschat Kathy , Lowry Phil , Sills Stephen
Published: July 2019

The discovery of the Jubilee field in the Tano Basin of Ghana opened a new play in the deep water of the Atlantic transform margins. The field is a late Cretaceous combination structural-stratigraphic trap associated with topography created by the transform tectonics during the opening of the Atlantic. Prior to the drilling of the discovery well, the African transform margin had seen very little deep-water exploration with only nine wells drilled over a margin more than 2000 km (1243 mi) long. The field was discovered in June 2007 with the Mahogany 1 well, which encountered 98 m (322 ft) of high-quality oil pay in a Turonian-aged fan sequence trapped in a combination structural-stratigraphic trap. Subsequent to the discovery, accelerated appraisal and phased development resulted in first production in November 2010. The field is currently producing more than 100,000 BOPD and has a planned peak production of 120,000 BOPD. The discovery has resulted in an industry-wide exploration campaign of over 50 wells in the last 8 years. These have resulted in a number of additional discoveries and to date at least one additional development. This chapter describes the exploration play concept and the geology of the field.
The Windjammer Discovery: Play Opener for Offshore Mozambique and East Africa
Authors: Fletcher Tom
Published: July 2019

The Windjammer prospect spud in late 2009, leading to the discovery of 190 trillion cubic feet (tcf) in the offshore region of the Rovuma Basin in northern Mozambique. The key reservoirs are composed of stacked submarine fan complexes from the Oligocene, Eocene, and Paleocene epochs of the lower Tertiary. The submarine fans form traps truncating against the leading edge of the Palma fold and thrust belt. The high-permeability reservoirs are thick, widespread, and very well connected, making them ideally suited for long-term natural gas production and liquid natural gas (LNG) exports. The massive amount of gas found offshore Rovuma has the potential to elevate Mozambique to the world’s third-largest exporter of natural gas.
The Jansz-Io Gas Field, Northwest Shelf Australia: A Giant Stratigraphic Trap
Authors: Jenkins C. C. , Duckett A. , Boyett B. A. , Glenton P. N. , Mills A. A. , Schapper M. C. , Williams M. A. , McPherson J. G.
Published: July 2019

The Jansz-Io gas field is located in production licenses WA-36-L, WA-39-L, and WA-40-L within the Carnarvon Basin, northwest shelf, Australia. It is 70 km (43 mi) northwest of the Gorgon gas field, 140 km (87 mi) northwest of Barrow Island, and 250 km (155 mi) from Dampier on the northwest coast of Western Australia. Water depths vary from 1200 to 1400 m (3937 to 4593 ft) across the field.

The Jansz-Io gas field was discovered in 2000 by the Jansz-1 exploration well. A three-dimensional (3-D) seismic survey was acquired in 2004, and a further five wells were drilled between 2000 and 2009 to further delineate the field extent and size and characterize the resource to facilitate progress toward development.

The Jansz-Io hydrocarbon trap extends over 2000 km2 (772 mi2) with both structural (faulted anticline) and stratigraphic (reservoir pinch-out) components. The stratigraphic component of the trap is defined by the reservoir extent, which is limited by depositional downlap to the northwest, and erosional truncation by Upper Jurassic and Lower Cretaceous unconformities to the southeast.

The reservoir comprises muddy, bioturbated, predominantly very fine- to fine-grained sandstones deposited in a shallow-marine environment and is divided into two units. The upper wedge reservoir has 25 to 35% total porosity with 10 to 1000 md permeability, and the lower wedge reservoir has 15 to 25% porosity with 0.01 to 10 md permeability. Both reservoir units are expected to contribute gas during production.

The original gas in place (OGIP) for the Jansz-Io Oxfordian reservoir has a probabilistic range from 320 to 946 Gm3 (11 to 33 tcf), with a P50 value of 632 Gm3 (22 tcf). The ultimate recovered gas for the field will depend on both the development plan and the reservoir performance over field life. For the current 15-well development plan, the resource estimates range from 201 to 442 Gm3 (7 to 16 tcf).

The Jansz-Io gas field is a key part of the greater Gorgon liquified natural gas (LNG) project and will supply gas to the LNG plant that is being constructed on Barrow Island. The development concept includes subsea completions from three drill centers placed on the seafloor connected to a subsea production pipeline to carry gas to the LNG processing plant.

For the first stage of field development, 10 development wells were successfully drilled and completed during 2012 and 2014. The second drilling campaign is planned to commence after field start-up with the timing dependant on field performance.
Las secciones sindicales en la negociación colectiva: convenios colectivos erga omnes y control sindical
Authors: Mata Diestro Héctor
Published: July 2019

En este artículo se aborda la negociación colectiva a través de las secciones sindicales, como parte del contenido esencial del derecho fundamental a la libertad sindical. Para ello se procede a un análisis legislativo y jurisprudencial, tratando algunas de las problemáticas derivadas de esta cuestión, para posteriormente ponerlo en relación respecto a los derechos de información y control sindical. De lo cual se concluye la necesidad de potenciar, a través de la negociación colectiva, el control sindical de las empresas. A estos efectos, se realizan una serie de propuestas concretas.
El papel de la negociación colectiva como herramienta de reforzamiento de las representaciones sindicales más allá de la empresa
Authors: Esteban Legarreta Ricardo
Published: July 2019

El artículo aborda a través del análisis de algunos Convenios Colectivos de alcance estatal cómo las representaciones sindicales favorecen la representación de los trabajadores más allá de la empresa. Para ello, se describen las características más importantes de la Sección Sindical para explicar a continuación que la Sección de ámbito supraempresarial gozará de prerrogativas en tanto en cuanto, con carácter general, esté pactada en Convenio Colectivo. El texto aborda igualmente la posibilidad de puesta en marcha de Secciones Sindicales de sector. La segunda parte de la comunicación se dedica a los Delegados de alcance supraempresarial, deteniéndose en primer lugar en los Delegados Sindicales de grupo, regulados detalladamente en algunos Convenios Colectivos de grupo de empresas, convenios que optan claramente por potenciar a las representaciones sindicales. El texto se detiene en el análisis de otras opciones más clásicas –el Delegado de grupo de empresas regulado en Convenio sectorial—y también de posibilidades más innovadoras y de especial utilidad como los denominados Delegados Sindicales de sector.
Communicative differences between emergent and traditional parties: An analysis of Facebook posts from Spain’s 2015 general election campaign
Authors: Fenoll Vicente , Cano-Orón Lorena
Published: July 2019

Las redes sociales han supuesto una revolución para la comunicación política, posibilita a los partidos tener un canal de comunicación masivo con capacidad de personalizar y crear una comunicación directa con los ciudadanos. Este estudio analiza las publicaciones de los principales partidos políticos españoles en Facebook durante la campaña de las elecciones de 2015. Desde una perspectiva cuantitativa, comparamos la frecuencia de publicación y el contenido de los mensajes a través de un análisis computarizado. Los resultados señalan que existen diferencias entre partidos tradicionales y emergentes en la gestión de las páginas de Facebook.
Periodistas valencianos de los años 20 y 30. Algunos nombres de referencia de la generación del exilio de 1939
Authors: Viadel Girbés Francesc , Pelliser Rossell Nel.lo
Published: July 2019

Durante los años 20 y 30 del siglo XX surgió en el País Valenciano una generación de periodistas entre los que se encuentran algunas de las firmas más destacadas del periodismo valenciano de todos los tiempos. Paradójicamente, se trata de trayectorias que han quedado desdibujadas por las circunstancias históricas, fundamentalmente por el exilio republicano. Este trabajo parte de la selección de aquellos más relevantes, desde una perspectiva periodística profesional. Atendiendo a su trayectoria y su producción, se han seleccionado los más relevantes para reconstruir sus biografías profesionales como punto de partida para su recuperación como grupo y el posterior estudio de su obra.
El tratamiento audiovisual de los menores de edad en los filmes que recrean el contexto de la dictadura franquista. Estudio del cine español realizado durante la etapa democrática (1978-2015)
Authors: Corral Rey María Nieves
Published: July 2019

La atención del presente estudio se ha centrado en el estudio del tratamiento audiovisual del personaje menor de edad como protagonista integrado en filmes españoles realizados durante la etapa democrática (1978-2015) e inspirados en el contexto de la dictadura franquista. Para su exploración se ha elaborado una ficha que recoge tres dimensiones: física, psicológica y sociológica. La metodología utilizada ha sido el estudio fílmico, enmarcado en el análisis de contenido, y la muestra la integran trece filmes que responden a las características anteriormente descritas. Las conclusiones apuntan a la presencia de una serie de metáforas relevantes, que desarrollan un hilo narrativo en estos personajes, así como la omisión de sus raíces familiares.
La Economía del Bien Común en la prensa española (2008-2017): una década de parcialidad y silencio
Authors: Fernández Beltrán Francisco
Published: July 2019

La Economía del Bien Común (EBC) se presenta como uno de los sistemas económicos alternativos al capitalismo que mayor crecimiento ha experimentado. El tratamiento por parte de la prensa española durante la primera década de desarrollo de este movimiento (2008-2017) no se corresponde con ese nivel de expansión, lo que condena a la EBC a ser una víctima de la teoría de la espiral del silencio descrita por Noelle-Neumann (1995). La investigación analiza la presencia del movimiento en las dos principales cabeceras generalistas de España (El País y El Mundo)y en las de ámbito económico (Expansión y Cinco Días).
Mujer, música y Transición. Una perspectiva desde el diario El País
Authors: Pajón Fernández Alicia
Published: July 2019

En este artículo se busca indagar en los artículos relacionados con la música publicados en El País entre 1976 y 1982 la visión que se da de las artistas y la presencia de las mujeres como redactoras de información musical. Se analiza cómo el canon que esta publicación diseña en torno a la música en la Transición incluye o no a las artistas femeninas y la imagen que se proyecta de éstas. Observamos, además, los perfiles de las mujeres que consiguieron hacerse hueco en la redacción, como es el caso de Mercedes Domenech, Rosa María Pereda o Bel Carrasco. This article seeks to delve into the articles published about music by El País between 1976 and 1982 the perspective given towards female women and the women’s presence as musical journalists. We will analyze how the canon designed by the publication around music in the Transición includes or not certain female artists as well as the image that the newspaper projects of them. We will also look at the profiles of those women who did made a name for themselves in the publication as critics, such as Mercedes Domenech, Rosa María Pereda or Bel Carrasco.
Creando poder: la evolución de la autoridad docente en España
Authors: Lázaro Herrero Luján , García Redondo Eva
Published: July 2019

Este trabajo pretende abordar el tema de la autoridad del profesorado ya que se ha convertido en un problema que desborda las barreras educativas, para convertirse en un asunto con entidad política. Para ello, realizamos un análisis de la evolución de la autoridad del docente a lo largo de los dos últimos siglos, contemplada a partir de los diferentes desarrollos legislativos. Como unidades de análisis, hemos tomado las leyes educativas que arrancan en el año 1857, con la Ley Moyano, hasta nuestros días, así como los desarrollos normativos surgidos al respecto a nivel autonómico. El estudio de la normativa, desde una perspectiva histórica, nos va a permitir no solo constatar el papel que en cada momento social se le ha dado al docente, y cómo se ha recogido este a través de las regulaciones, sino la evolución del concepto de autoridad y el valor otorgado en cada época.
Contribuições para uma genealogia da pena de morte: desnudando a “índole pacífica” do povo brasileiro
Authors: Salla Fernando Afonso , Teixeira Alessandra , Marinho Maria Gabriela S. M. C.
Published: July 2019

O artigo propõe uma genealogia das disputas em torno da pena de morte no Brasil, apresentando os discursos que nortearam o debate, os instrumentos legais que estipularam essa pena e as práticas extralegais que indiretamente a promoveram. Apontamos três níveis de previsão para sua aplicação: aos crimes militares; à dissidência política e à criminalidade comum. Identificamos a legislação adotada e os debates travados entre os anos 1920 e 1950, sendo a década de 50 decisiva para que o discurso da pena de morte passasse a ser mobilizado como principal recurso à contenção da criminalidade comum. Contrariando a retórica da “índole pacífica” do povo brasileiro, demonstramos que a aparente rejeição à inserção da pena de morte no ordenamento jurídico é contraposta pelo apoio popular às formas de justiçamento que, a partir dos anos 50, se cristalizarão em práticas rotineiras de execuções sumárias de suspeitos, esquadrões da morte e na violência policial de um modo geral, esvaziando o debate em torno de sua previsão legal.
Resilient Bodies, Residual Effects
Authors: Noeth Sandra
Published: July 2019

What does it take to cross a border, and what does it take to belong? Sandra Noeth examines the entangled experiences of borders and of collectivity through the perspective of bodies. By dramaturgical analyses of contemporary artistic work from Lebanon and Palestine, Noeth shows how borders and collectivity are constructed and negotiated through performative, corporeal, movement-based, and sensory strategies and processes. This interdisciplinary study is made urgent by social and political transformations across the Middle East and beyond from 2010 onwards. It puts to the fore the residual, body-bound structural effects of borders and of collectivity and proceeds to develop notions of agency and responsibility that are immanently bound to bodies in relation.