bluuebunny/crossref_metadata_2025 huggingface dataset:
Dukungan Sosial terhadap Kualitas Hidup Perempuan Infertilitas di Kabupaten Manggarai
Authors: Banul Maria Sriana , Halu Silfia A.N , Dafiq Nur , Afrinita Maria , Serni Elisabet J.
Published: December 2024

ABSTRACT Social support has an important role in improving the quality of life. Women who receive appropriate social support can improve their quality of life, including increasing self-confidence, reducing pressure, stress and depression, as well as increasing hope and optimism in facing infertility problems. The aim of the research is to analyze the influence of social support on the quality of life of women experiencing infertility in Manggarai Regency. This research is quantitative with a cross sectional approach. The sampling technique used was purposive sampling with a total of 90 people. The characteristics of this study are women who have been married for 1 year and have not had children without using contraception. Data analysis was carried out using Chi Square. There is a relationship between social support and the quality of life of infertile women (p value 0.003<0.05). Understanding the positive impact of social support on the quality of life of women experiencing infertility can be a reference for us to develop better interventions and support programs by providing adequate social support. Keywords: Social Support, Women's Infertility, Quality of Life ABSTRAK Dukungan sosial memiliki peran penting dalam meningkatkan kualitas hidup. Perempuan yang mendapat dukungan sosial yang tepat dapat meningkatkan kualitas hidup termasuk meningkatkan kepercayaan diri, mengurangi tekanan, stres dan depresi, serta meningkatkan harapan dan optimisme dalam menghadapi masalah infertilitas. Tujuan penelitian untuk mengalisis pengaruh dukungan sosial terhadap kualitas hidup perempuan yang mengalami infertilitas di Kabupaten Manggarai. Penelitian ini adalah kuantitatif dengan pendekatan cross sectional. Tehnik pengambilan sampel yang digunakan adalah purposive sampling dengan jumlah 90 orang. Karakteristik penelitian ini adalah perempuan yang sudah menikah selama 1 tahun dan belum memiliki keturunan tanpa menggunakan alat kontrasepsi. Analisis data dilakukan dengan Chi Square. Ada hubungan dukungan sosial terhadap kualitas hidup perempuan infertilitas (p value 0,003<0,05). Dengan memahami dampak positif dari dukungan sosial terhadap kualitas hidup perempuan yang mengalami infertilitas dapat menjadi acuan bagi kita untuk mengembangkan intervensi dan program dukungan yang lebih baik dengan pemberian dukungan sosial yang memadai. Kata Kunci: Dukungan Sosial, Perempuan Infertilitas, Kualitas Hidup
Efektivitas Akupresur dan Prenatal Yoga terhadap Penurunan Nyeri Punggung Bawah Ibu Hamil Trimester III di Wilayah Kerja Puskesmas Telagasari
Authors: Masluroh Masluroh , Sutinah Titin
Published: December 2024

ABSTRACT During the third trimester of pregnancy, many pregnant mothers experience complaints or discomfort, one of which is lower back pain as the fetal weight increases and the uterus grows. An attempt to alleviate the mother's lower back pain could be with alternative therapies with acupressure and prenatal yoga. The aim of this survey is to find out how the effectiveness of acupressure and prenatal yoga to the reduction of lower back pain in pregnant mothers of the third trimester in the Public Health Center of Telagasari working region in 2024. The results of the study can be interpreted that pregnant women who had reduced levels of pain after doing Yoga had more respondents who had no pain, most of whom had 11 (73.3%) respondents, while mothers who did Acupressure had 9 (60.0%) respondents. So the results of data analysis use the paired simple t test. The resulting value and ρ-value were 0.000<0.05. Pregnancy yoga exercises (Prenatal Gentle Yoga) are part of non-pharmacological therapy that can reduce pain. Yoga exercises carried out in the third trimester of pregnancy can reduce complaints felt by pregnant women during the third trimester, one of which is back pain. Keywords: Prenatal Yoga, Acupressure, Back Pain  ABSTRAK Selama trimester ketiga kehamilan, banyak ibu hamil yang mengalami keluhan atau ketidaknyamana, salah satunya nyeri punggung bagian bawah ini karena berat badan janin meningkat dan rahim ibu makin membesar. Upaya untuk mengurangi nyeri punggung bagian bawah ibu tersebut bisa dengan pengobatan alternatif dengan akupresur dan prenatal yoga. Tujuan peneltian ini untuk mengetahui bagaimana efektivitas akupresur dan prenatal yoga terhadap penurunan nyeri punggung bawah ibu hamil trimester III di wilayah kerja puskesmas telagasari tahun 2024. Metode penelitian ini menggunakan quasi eksperimen dengan 30 responden teknik pengambilan data menggunakan tekhnik purposive sampling. Hasil penelitian dapat diinterpretasikan bahwa ibu hamil yang pengurangan tingkat nyeri setelah melakukan Yoga mempunyai lebih banyak responden yang Tidak nyeri sebagian besar dengan jumlah responden 11 (73,3%) , sedangkan ibu yang melakukan Akupresur dengan jumlah responden 9 (60,0%). Jadi hasil analisa data menggunakan uji paired simple t test. didapatkan hasil nilai dan ρ-value 0,000<0,05. Senam yoga kehamilan (Prenatal Gentle Yoga) merupakan bagian dari terapi non farmakologis yang dapat menurunkan nyeri. Senam yoga yang dilakukan pada kehamilan trimester III dapat mengurangi keluhan yang dirasakan ibu hamil selama trimester III salah satunya yaitu nyeri punggung. Kata Kunci: Prenatal Yoga, Akupresure, Nyeri Punggung
Blood sugar level changes on cognitive function among students undertaking part‐time employment
Authors: Pratama Irza Haicha , Karan Jag , Harahap Alvin Abrar
Published: December 2024

Background: Part-time work among students has become a common phenomenon in higher education, often driven by financial constraints, daily needs, and the desire for independence. However, the integration of work and study can pose significant challenges, particularly concerning the heavy workload of assignments and potential health risks. Cognitive functions, which include attention, memory, language, and visuospatial skills, can be affected by various factors, including health disorders such as hyperglycemia. Hyperglycemia, or high blood glucose levels, is often associated with a decline in cognitive function. In Indonesia, the prevalence of hyperglycemia is increasing, with the highest undiagnosed rates in the age group 17-29 years.
Purpose: To analyze the relationship between blood glucose levels and cognitive function among students undertaking part-time employment.
Method: Applying an observational analytical approach with a cross-sectional design. The sample comprised 100 part-time students from the Management Study Program at the Faculty of Economics, Prima Indonesia University. Data collection was carried out using observation sheets, and the Spearman Rank Correlation test was applied for analysis.
Results: Most respondents were 18 years old (45%), with males comprising 55% of the sample. A majority (53%) had been working part-time for less than three months, while 47% had worked for over three months. Blood glucose levels, assessed using a glucometer, ranged from 66 to 217, with a median of 96. Cognitive function, evaluated through the Digit Symbol Substitution Test (DSST), showed scores ranging from 17 to 53, with a median of 38.
Conclusion: There is a significant relationship between cognitive function and blood glucose levels among part-time working students.
Consumer Inertia and Dynamic Price Competition
Authors: Wiśnicki Bartłomiej
Published: December 2024

Celem opisanych badań była analiza decyzji firm dotyczących ceny i jakości w warunkach, w których konsumenci nie mogą w pełni ocenić produktu, przy dokonywaniu wyboru muszą polegać na anegdotycznych dowodach oraz wykazują inercję (nadmierne przywiązanie do wcześniejszych zakupów) w swoim procesie decyzyjnym. Aby przeanalizować zachowanie firm, zastosowano dwuokresowy model konkurencji cenowej, w którym firmy mogą również wybierać jakość swoich produktów. Konsumenci są świadomi cen, ale uczą się jakości produktu poprzez doświadczenie i dowody anegdotyczne, które przejawiają się w prostych regułach decyzyjnych. Uzyskano analityczne wyniki w postaci równowagi Nasha w strategiach cenowych i dotyczących jakości dla różnych poziomów inercji konsumentów oraz przeprowadzono statykę porównawczą wyników. Zauważono, że zgodnie z przewidywaniami inercja czyni rynek mniej konkurencyjnym, ponieważ firmy zyskują monopolistyczną władzę nad przywiązanymi konsumentami. Inercja prowadzi jednak również do zwiększonej konkurencji o konsumentów nieprzywiązanych oraz do poprawy jakości produktów. W związku z tym w pew¬nych sytuacjach może przyczynić się do obniżki ceny produktu i tym samym do poprawy dobrobytu rynkowego.
Prehistoric Schematic Rock Art
in the Eastern Adriatic: the discovery of Rock Art at the Badanj II rock
shelter (Bosnia and Herzegovina) viewed from the Western Mediterranean
Authors: Barciela González Virginia , Ruiz-Redondo Aitor , Vujnović Ante , Vukosavljević Nikola
Published: December 2024

Research on post-Palaeolithic schematic rock art has changed substantially since its identification and definition almost a century ago. In the areas where this phenomenon is extensively studied (such as South and East Iberia), a chronological and cultural sequence has been established. This is due to the large number of rock art finds and the study of their archaeological context, which includes numerous portable art analogies. Based on this documentation, it has been proposed that its origins lie in the Early Neolithic and that it persisted until the Chalcolithic (c. 6th – 3rd millennium cal BC) or even, in some areas, until the Bronze Age. In this paper, we present the recent discovery of graphic motifs with similar characteristics in the Badanj II rock shelter. In the context of other finds in the Western and Central Mediterranean, this is an interesting indicator that leads us to suggest a connection between this graphic expression and the dispersion, establishment, and consolidation of Neolithic groups in Europe.
(Peri)urbano vrtlarstvo u Saloni? O nalazu ollae perforatae u salonitanskome urbs orientalis u kontekstu vrtlarstva na istočnome
Jadranu u rimskome razdoblju
Authors: Konestra Ana
Published: December 2024

U radu se raspravlja o šupljim posudama pronađenima tijekom zaštitnih istraživanja na trasi plinovoda u Solinu, a koja je zahvatila istočni dio antičke Salone (urbs orientalis). Posude se karakteriziraju tipološki i funkcionalno te se na temelju analogija identificira njihovo korištenje u hortikulturi ili voćarstvu, odnosno interpretira ih se kao ollae perforatae funkcionalne u presađivanju i transportu biljaka. Uzimajući u obzir topografiju područja nalaza unutar (pri)gradskoga rastera Salone, na temelju ovih posuda raspravlja se o mogućim asocijacijama pretpostavljenoga hortikulturnoga prostora s ranijim arhitektonskim nalazima. S obzirom na unikatnost takvih posuda u salonitonskome, ali i širem istočnojadranskom keramičkom korpusu, te uzimajući u obzir srodne i pretpostavljene indikatore antičke hortikulture, one se smještaju u širu raspravu o vrtlarstvu u rimskome razdoblje na tomu području te o društvenim praksama i širim implikacijama koje prate uspostavu i korištenje rimskih vrtova te njihovo ideološko i identitetsko značenje kao kulturnih krajolika.
Forenzična rekonstrukcija lica pomoću 3D računalne
tehnologije
Authors: Ćirić Irena , Mikulka Ana , Hincak Daris Zdravka
Published: December 2024

U radu je prikazan proces forenzične rekonstrukcije mekih tkiva lica kako bi se ispitala uspješnost primjene 3D računalnih metoda na lubanji osobe ekshumiranoj iz masovne grobnice iz Drugog svjetskog rata i poslijeratnog razdoblja. Lubanja neidentificirane osobe pripada jednoj od ukupno 294 ekshumirane žrtve sa sedam lokacija istraženih 2018. godine na području Gračana u Zagrebu. Nakon antropološke analize, koja obuhvaća kraniofacijalnu antropometriju i 3D skeniranje lubanje, proces rekonstrukcije lica izveden je u standardnim programima za 3D oblikovanje: Blender, MakeHuman i OrtogOnBlender. Postupak osjenčavanja 3D modela pri računalnoj obradi omogućio je pretvaranje digitalne rekonstrukcije lubanje u trodimenzionalni prikaz lica, što predstavlja završnu fazu procesa. Rekonstrukcijom je prikazano kako se i iz izazovnog koštanog materijala može pružiti mnoštvo podataka korisnih u procesu identifikacije osoba. Daljnji razvoj forenzične rekonstrukcije lica ovisi o stvaranju opsežnih baza podataka i daljnjem istraživanju novih metoda.
PENERAPAN PROGRAM KKN MBKM KIMIA ASIK UNTUK MENINGKATKAN MINAT BELAJAR SISWA KELAS X DI SMAN 2 KOTA BENGKULU
Authors: Jamilah Tussadiah  , Alen Midiya  , Adeka Oktavianda  , Astri Hartati  , Rina Elvia
Published: December 2024

Program KKN MBKM bertajuk "Kimia Asik" dilaksanakan di SMAN 2 Kota Bengkulu dengan tujuan meningkatkan minat belajar siswa kelas X terhadap pelajaran kimia melalui praktikum pembuatan es krim. Metode yang digunakan mencakup ceramah, diskusi, dan praktik. Siswa mempelajari prinsip-prinsip kimia seperti perubahan fisik, suhu, pembentukan emulsi, dan kristalisasi melalui metode konvensional. Hasil angket menunjukkan peningkatan minat belajar siswa yang signifikan setelah kegiatan ini, terutama dalam memahami aplikasi kimia dalam kehidupan sehari-hari. Guru juga memberikan tanggapan positif atas pendekatan interaktif ini. Program ini berhasil mengubah paradigma pembelajaran kimia dari sulit dan membosankan menjadi menarik dan relevan. Dengan eksperimen praktis, program ini tidak hanya meningkatkan pemahaman siswa terhadap konsep kimia, tetapi juga menumbuhkan rasa ingin tahu dan keterlibatan mereka dalam proses pembelajaran.
Analisis Perkembangan Kecerdasan Naturalis Anak Usia 5-6 tahun Ditinjau Dari Penerapan Media Busy Book
Authors: Ulfa Maria , Bafadal Usman , Ilyas Sitti Nurhidayah , Rusmayadi Rusmayadi , Musi Muhammad Akil , Djadir Djadir
Published: December 2024

Penelitian ini dilatarbelakangi oleh perlunya membantu terkhususnya anak di usia 5-6 tahun dalam mengembangkan intelegensi keadaan lingkungan sekitar melalui proses observasi secara langsung serta bermain busy book. Kecerdasan naturalis memegang kedudukan berharga dalam pertumbuhan anak usia dini. Sasaran mengenai pengkajian ini yakni menganalisis perkembangan kemampuan naturalis pada anak didik. Tujuan dari penelitian yakni untuk mengidentifikasi perkembangan media terhadap kemampuan naturalis sesuai dengan karakteristik anak serta kualitas produk busy book. Metode yang digunakan yaitu penelitian kualitatif dengan jenis deskriptif untuk mendeskripsikan terkait pengembangan busy book pada anak di usia 5-6 tahun TK Alkhairaat Bahoea Reko-Reko. Penelitian ini memakai teknik pengumpulan data observasi, wawancara serta dokumentasi. Hasil yang telah ditemukan menjelaskan bahwa dengan menggunakan media busy book anak sudah mencapai aspek perkembangan yang diteliti oleh peneliti. Media busy book memiliki pengaruh positif melalui pengembangan yakni kecerdasan naturalis kepada anak usia 5-6 tahun. Anak-anak menunjukkan minat yang tinggi terhadap aktivitas yang disajikan dalam busy book dan aktif berpartisipasi dalam kegiatan tersebut. Berdasarkan analisis ini, memperoleh kesimpulan yaitu setelah penerapan dari media busy book efisien di dalam merangsang kemajuan di dalam kecerdasan naturalistik bagi anak usia 5-6 tahun. Anak-anak menunjukkan minat yang tinggi terhadap aktivitas yang disajikan dalam busy book, serta mengalami peningkatan dalam pemahaman anak-anak tentang berbagai konsep alam. Guru dan orang tua juga melaporkan perubahan positif dalam perilaku dan pengetahuan anak-anak setelah menggunakan busy book secara teratur.
Analisis Pola Interaksi Guru Dalam Membangun Karakter Kemandirian Anak Usia dini
Authors: Oktaviana Sovia , Elan Elan , Purwati Purwati
Published: December 2024

Penelitian ini bertujuan untuk menganalisis pola interaksi guru dalam membentuk karakter kemandirian pada anak usia dini melalui tinjauan literatur. Kemandirian merupakan aspek penting dalam perkembangan anak usia dini yang memengaruhi kemampuan mereka dalam menghadapi tantangan dan mengambil inisiatif secara mandiri. Melalui analisis terhadap literatur yang relevan, artikel ini mengidentifikasi berbagai pola interaksi guru yang efektif dalam membantu anak usia dini membangun karakter kemandirian. Data yang diperoleh dari literatur akan dianalisis secara sistematis untuk mengidentifikasi pola-pola interaksi guru dalam membentuk karakter kemandirian pada anak usia dini. Dari hasil tinjauan literatur ini, dapat disimpulkan bahwa interaksi antara guru dan anak usia dini memainkan peran yang sangat penting dalam pembentukan karakter kemandirian. Pola-pola interaksi yang efektif dan edukatif, seperti memberikan dukungan, memberikan tanggung jawab, dan membangun hubungan yang positif dengan anak-anak, memiliki dampak yang signifikan dalam membantu anak-anak mengembangkan kemandirian. Temuan dari penelitian ini diharapkan dapat memberikan wawasan yang berharga bagi pendidik dan praktisi dalam merancang strategi pembelajaran yang mendukung pengembangan kemandirian anak usia dini.
Pengembangan Instrumen Skala Kemampuan Komunikasi Interpersonal Pada Mahasiswa Pendidikan Guru Pendidikan Anak Usia Dini
Authors: Sari Yulia Novita , Fajhriani N Dyla , Arfa Umikalsum , Jariah Nurul , Sultoni Agus
Published: December 2024

Penelitian ini bertujuan untuk mengembangkan instrumen skala kemampuan komunikasi interpersonal sehingga menghasilkan instrumen yang valid dan reliabel dalam mengukur tingkat kemampuan komunikasi interpersonal pada mahasiswa. Penelitian ini menggunakan metode Research and Development (RD). Subjek dalam penelitian ini adalah 32 mahasiswa semester tujuh. Hasil uji validitas dengan menggunakan dua cara, yaitu validitas konstruk (construct validity) dan validitas isi (content validity). Pada hasil uji validitas dihasilkan 29 item pernyataan valid dan 11 item pernyataan tidak valid. Selanjutnya dilakukan uji reliabilitas dengan  nilai Cronbach’s Alpha 0,910 yang memiliki kualifikasi reliabilitas yang sangat tinggi. Dengan demikian, instrumen siap digunakan. Berdasarkan hasil uji validitas dan reliabilitas tersebut, instrumen kemampuan komunikasi interpersonal pada mahasiswa yang dikembangkan telah memenuhi kriteria validitas serta termasuk ke dalam kategori validitas dan reliabilitas sangat tinggi, sehingga instrumen skala kemampuan komunikasi interpersonal pada mahasiswa dapat dikatakan layak untuk mengukur tingkat kemampuan komunikasi interpersonal.
Filosofi Pendidikan Islam: Membentuk Jiwa Anak Usia Dini Sebagai Cerminan Fitrah Dan Akhlak Mulia
Authors: Achmad Fatoni
Published: December 2024

Pendidikan Islam memiliki peran krusial dalam membentuk karakter dan moral anak usia dini yang berada dalam keadaan fitrah, dengan penekanan pada nilai-nilai akhlak mulia. Penelitian ini bertujuan untuk mengkaji dan menganalisis filosofi pendidikan Islam dalam kaitannya dengan pembentukan jiwa anak usia dini sebagai cerminan fitrah dan akhlak mulia. Metode penelitian yang digunakan adalah library research. Teknik pengumpulan data dilakukan melalui beberapa langkah, yaitu pengumpulan dilakukan literatur, klasifikasi literatur, dan analisis isi. Untuk memastikan keabsahan data, dilakukan uji kredibilitas melalui triangulasi teknik. Hasil penelitian menunjukkan bahwa filsafat pendidikan Islam menekankan pentingnya pendidikan bukan hanya sebagai transfer ilmu pengetahuan, tetapi juga sebagai pembentukan karakter, akhlak, dan spiritualitas anak. Pendidikan dalam Islam memandang anak sebagai amanah Allah dengan fitrah yang suci, di mana orang tua dan guru berperan sebagai fasilitator untuk menjaga dan mengarahkan potensi tersebut. Pendidikan Islam menekankan keseimbangan antara perkembangan intelektual, emosional, dan spiritual, yang bertujuan membentuk anak dengan kesadaran moral yang kuat, siap menghadapi kehidupan dengan prinsip-prinsip ilahiah dan tanggung jawab sosial.
Analisis Perkembangan Bahasa Daerah Tidore Pada Anak Kelompok B Di PAUD Rirorano Topo 3 Kota Tidore Kepulauan
Authors: Taib Bahran , Arifin Andi Agustan , Wondal Rosita , Ramli Karlina
Published: December 2024

Tujuan penelitian ini untuk memahami perkembangan bahasa daerah Tidore pada anak kelompok B PAUD Rirorano Topo 3 Kota Tidore Kepulauan. Metode penelitian kualitatif dengan memakai pendekatan deskriptif dengan subjek penelitian sebanyak 11 anak dan 2 guru. Teknik pengumpulan data yang dilakukan ialah observasi, wawancara, serta dokumentasi. Teknik analisis data terdiri dari pengumpulan data, reduksi data, penyajian data, serta penarikan kesimpulan. Hasil penelitian ini memperlihatkan perkembangan bahasa daerah Tidore pada anak kelompok B di PAUD Rirorano terlihat dengan 3 indikator yakni: 1). Mengucapkan kata yang tepat, dari 11 anak, terdapat 7 anak yang sudah mampu mengucapkan kata sederhana dalam bahasa Tidore, sedangkan 4 anak lainnya belum mampu mengucapkan kata dalam bahasa Tidore dengan tepat, karena ketika ditanya anak hanya diam tidak bereaksi apa-apa. Hal ini karena ketika guru mengajar anak tidak menyimak apa yang dikatakan guru melainkan anak bermain dengan teman dibelakang. 2). Memahami bahasa daerah Tidore, dari 11 anak, terdapat 5 anak yang sudah mampu memahami bahasa daerah Tidore, sedangkan 6 anak lainnya masih kesulitan, terutama dalam mengulang kalimat yang rumit. Kemampuan anak dalam memahami penjelasan guru tentang bahasa Tidore juga sangat terbatas. Hal ini diperparah oleh metode pembelajaran yang kurang menarik, sehingga anak-anak cenderung merasa malas selama proses pembelajaran bahasa daerah tersebut. 3). Berbahasa daerah Tidore, dari 11 anak, terdapat 5 anak yang mampu berbahasa daerah Tidore, sedangkan 6 anak lainnya belum lancar dan belum bisa berbahasa daerah Tidore dikarenakan di rumah mereka hanya menggunakan bahasa Indonesia sehingga pada saat berbahasa daerah Tidore anak terbata-bata dalam pengucapannya.
Teachers’ Attitude Towards the Topic of Dialects in Polish Schools
Authors: Osowski Błażej
Published: December 2024

The inclusion or exclusion of topics in the core curriculum directly influences the content covered in lessons, with dialect-related issues receiving limited attention. Despite their marginal role in the curriculum, dialects are significant in shaping local identity, whether genuinely or symbolically. This raises questions about whether teachers independently integrate dialectal content into their lessons, their perceived need to acquaint students with such topics, their attitudes toward dialects, and the sources of their knowledge. To explore these questions, an online survey was conducted among teachers.
Keywords: dialectology, school, core curriculum, teachers’ perspectives.
Epidemiological and Clinical Profile of Irritable Bowel Syndrome among Medical Students in Conakry
Authors: Sarifou Diallo Mamadou , Oumarou Youssouf , Boubacar Kanté , N'Djouria Diallo Abdourahmane , Kadiatou Diallo , Amadou Wann Thierno , Djenabou Diallo , LamineYaya Bah Mamadou , Mamadou Diakhaby , Aliou Kanté Mamadou , Djibril Sylla , Dramane Soro
Published: December 2024

Introduction: Irritable bowel syndrome (IBS) represents a real public health problem. It is a gastrointestinal disorder characterized by chronic abdominal pain and intestinal transit abnormalities, in the absence of identifiable organic substrate. It is a clinical entity whose prevalence, impact on the quality of life of individuals and the health costs generated are significant. The aim of this study was to determine the prevalence of irritable bowel syndrome, clinical aspects, triggering and/or aggravating and calming factors in medical students.

Methods: This was a descriptive cross-sectional study. It was carried out from June 8, 2023 to December 8, 2023, i.e. a period of six (06) months. The study took place in the faculties of medicine of the Gamal Abdel Nasser University of Conakry and the University of La Source and meeting the criteria of Rome IV.

Results: Three hundred cases of IBS out of 633 surveyed, representing a prevalence of 47.4%, were recorded. There was a male predominance with a M/F sex ratio of 2.13. The average age was 22.51 years with extremes of 18 and 35 years. The main clinical signs were constipation in 74.4%, abdominal pain (61.4%), abdominal bloating 49.77%, diarrhea 31.4% and alternating diarrhea/constipation 13.02%. The most frequent extradigestive manifestations were: headaches 60%, physical asthenia 35% and dizziness 29%. The main triggering factors were: psychological factors 46% and dietary factors (cassava 40.4%, okra 32%, beans 20.3%). The calming factors were: the emission of gas (farts) in 68% of cases, defecation in 57.9% of cases, eating meals in 32% of cases, sleep in 15.5% of cases.

Conclusion: IBS is a public health problem that impairs the quality of life of those affected. Abdominal pain, constipation and abdominal bloating constitute the symptomatic triad. Stress is a triggering factor for the symptoms.
HBsAg Seroclearance and Seroconversion: Incidence and Patient Profiles at the Centre Hospitalier Universitaire Yalgado Ouedraogo
Authors: PARE Stella Line Emmanuella , NAPON-ZONGO P Delphine , Emile KY Lawagoulé Joseph , DIALLO Mamadou Sarifou , Sandrine MOB Hema-Soudre , BANTENGA Daouda , Ben Moctar Abdou Djibo , ZONGO Abdoul Rasmané , SESSOUMA Arouna , SOMDA Sosthène , SOMBIÉ Arsène Roger
Published: December 2024

Introduction: HBsAg seroclearance is a rare event in the natural history of chronic hepatitis B virus (HBV) infection. Data on HBsAg seroclearance and seroconversion are scarce in Burkina Faso. This study assessed the incidence and determined the profile of patients with HBsAg clearance and conversion at the Yalgado Ouédraogo University Hospital.

Patients and Methods: This was a retrospective descriptive cross-sectional study conducted from 1 January 2006 to 31 July 2023, i.e. 17 years and 6 months, at the Yalgado Ouédraogo University Hospital. Patients were included who were chronic HBV carriers who had lost HBsAg spontaneously or after the introduction of nucleoside analogue therapy, had a viral load of HBV on admission and were negative for antibodies to hepatitis C virus (HCV), hepatitis D virus (HDV) and human immunodeficiency virus (HIV). HBsAg seroclearance was defined as serum HBsAg negativity, checked at least once, and seroconversion as the disappearance of serum HBsAg and the appearance of anti- Bs antibodies > 10 IU/ml.

Results: Of the 1507 patients in our cohort, 27 lost their HBsAg during the study period. The overall incidence of HBsAg loss was 1.8% and 55.5% of patients seroconverted to HBsAg within 12 months of HBsAg loss. The mean age of patients on admission was 31.3 ± 8.9 years, with a sex ratio of 2. The mean age of patients at the time of HBsAg loss was 39.9 ± 10.2 years. The mean duration of HBsAg carriage was 9 ± 5 years. All patients were inactive carriers. Untreated patients represented 74.1% of the cohort. Quantitative HBsAg was less than 100 IU/mL in 81.8% of patients, and 88% of patients had undetectable DNA before loss of HBsAg.

Conclusion: Although HBsAg seroclearance is associated with a good long-term prognosis, it remains a rare event. Patients at risk of developing hepatocellular carcinoma (HCC) after HBs seroclearance should be monitored at intervals that can be determined on the basis of further studies.
Chemistry Profile and Biological Activity of Campnosperma auriculatum Extracts
Authors: MUHARINI RINI , LESTARI IRA , ERSANDO  , MASRIAN  , PUTRI YANA AISYA , GERINA FEBRILIA , OLA ANTONIUS RB
Published: December 2024

As our ongoing investigation for bioactive natural products from tropical plant, we performed preliminary study on one of important tropical plants in West Kalimantan, Terentang putih, Campnosperma auriculatum. The aims were to determine effective solvent used for extraction, chemistry profile, total phenolic content, free-radical scavenging, cytotoxicity, and anti-termite activities of leaves, stems, and roots extracts of C. auriculatum. Variation of solvent for extraction was selected based on its polarisation, namely, ethanol, ethyl acetate, and n-hexane. The effectiveness of solvent was determined by observing the rendemen of each extract, where amount of sample and solvent volume, duration of extraction, temperature, and maceration technique were controled. Determination of total phenolic content was performed using Folin-Ciocalteu method. IC50 value for free-radical scavenging activity was calculated by plotting standard concentration and absorption data observed through DPPH method. Cytotoxicity evaluation was performed to each ethanolic extract against 4T1 cancer cell line using MTT assay. Anti-termite activity was conducted against Coptotermes curvignathus by calculating percentage of termite mortality and paper weight loss. This research showed that ethanol solvent was the most effective extraction solvent giving the highest yield in each part of plant. Phytochemically, all extracts showed that they contain phenolics and alkaloids. Ethanolic extract of stems showed the highest total phenolic content with 737.6 ± 0.56 ppm (GAE) and the most active as free-radical scavenger with IC50 value of 135.51 ± 0.91 ppm. Meanwhile, the roots extract exhibited pronounce cytotoxicity toward 4T1 cancer cell line with IC50 value of 1.55 ± 3.29 µg/ml and high selectivity index. Furthermore, the roots extract displayed most active as anti-termite as well as antifeedant. Hitherto, this study is the first report on  phytochemistry and biological activity from leaves, stems, and roots of C. auriculatum. Moreover, this plant can be explored further for its potential on medicinal and agricultural industries.
Physico-Chemical Properties and Mineral Identification of Salt Licks Soil in Segaliud Lokan Forest Reserve
Authors: MOHAMAD MAIDIN SITI NUR ANISA , SOMPUD JEPHTE , ABD RAHIM ISMAIL , SARJADI MOHD. SANI , MUSTA BABA
Published: December 2024

This study intended to describe the physicochemical and mineralogical properties of salt licks discovered in Segaliud Lokan Forest Reserve. The salt licks in this forest reported to be visited and used by wildlifes via camera trap studies. In order to understand this wildlife’s behavior, the physicochemical and mineralogical properties of the salt lick especially the salt lick soil are important to determine the cause of the wildlife visitation. Five salt licks area as well as controlled soils were selected. Water and rock samples were also collected for the comparison study. The physical characteristic of licks soil shows pH ranges from slightly acidic to alkaline, high moisture content (23.30% – 59.35%), wide range of organic matter content (0.38% – 9.65%) and electrical conductivity range between 41.82 µS/cm to 243.32 µS/cm which is higher than the controlled soils. The soil texture from the salt licks soils is mostly classified as loam. The result of chemical analysis shows that the concentration of elements is higher in the lick soil compared to the controlled soil such as Ca (1101.92 mg/kg – 11551.64 mg/kg), K (767.32 mg/kg – 2432.11 mg/kg), Na (85.83 mg/kg – 754.20 mg/kg), Mg (986.05 mg/kg – 5843.29 mg/kg) and P (47.23 mg/kg – 290.215 mg/kg). Water samples from salt licks area are rich in Ca (637.67 mg/L – 3074.25 mg/L) and Na (572.35 mg/L – 2554.63 mg/L) compared to river nearby. The mineral analysis indicated the appearance of clay such as illite, chlorite and smectite. As a conclusion, the salt lick soil’s pH varies from slightly acidic to alkaline (5.38 – 8.98) compared to controlled soils (4.54), The salt lick surface soils also show higher percentage of moisture content (69.38%) and soil electrical conductivity (78.41%) difference compared to controlled soils. Meanwhile the organic matter percentage in salt lick soils is slightly lower (48.85%) than the controlled soils (51.11%). The salt lick soils also exhibit higher elements concentration than the controlled soils such as average concentration of Ca (96.14%), K (86.09%), Na (89.51%) Mg (91.38%) and P (86.78%).
Assessment of Microplastics in the Surface Water of Mengkabong and Salut Rivers of Sabah, Malaysia
Authors: KALWANT-SINGH RAVEENA-KAUR , SOO CHEN-LI , CHEN CHENG-ANN
Published: December 2024

Microplastics in river water are a global risk to aquatic ecosystems due to their longevity in the environment, causing toxicity, ingestion by organisms, and bioaccumulation. However, knowledge and research on microplastic pollution are still scarce in Sabah, Malaysia, as no studies have been carried out before. Hence, this study aimed (1) to determine the occurrence of microplastics in the surface water of the Mengkabong and Salut Rivers in Sabah and (2) to assess the spatial variability in the concentration and characteristics of microplastics within these rivers. Microplastics were extracted, counted, and characterized for their shape, colour, size, and polymer. An independent t-test was used to compare microplastic abundance and characteristics between the two rivers, whereas Hierarchical cluster analysis was used to group the eight stations based on similarities in microplastics. This study detected microplastics at all stations, with a significantly higher concentration (p < 0.05) of microplastic in the Salut River (4.78±2.43 items/L) compared to those in the Mengkabong River (1.63±0.87 items/L). Fibre was the most abundant microplastic shape in both Mengkabong (78%) and Salut (57%), likely sourced from textile washing, fishing, and aquaculture activities in the vicinity. Transparent microplastics were prevalent in Mengkabong (30%), while black microplastics dominated in Salut (42%). Size distribution exhibited the opposite trend, with 74% larger-sized microplastics in Mengkabong but 63% smaller-sized microplastics in Salut. Polymer analysis revealed rayon (68%) dominance in Mengkabong, while polyethylene (34%) and rayon (33%) in Salut. Spatial heterogeneity of microplastics was evident through cluster analysis, categorizing stations into clean, moderately polluted, and polluted. Stations adjacent to areas with fewer land-based activities were clean with a low microplastics count, while areas with intense developments, residential, and fishing activities were polluted with high microplastic counts. This study underscores the presence of microplastics in Sabah's rivers, serving as a foundational reference for future research. It is also imperative to conduct regular monitoring of microplastics in the rivers of Sabah since it is anticipated that microplastics contamination will escalate in the coming years globally.
The Black Hole Mass-Gap and its Relation to Bekenstein-Hawking Entropy Leads to Potential Quantization of Black Holes
Authors: Haug Espen
Published: December 2024

We demonstrate that black holes likely have an energy or mass gap, E_g/c^2=m_g, that is of the order m_g\approx m_p^2/M_{BH}. Interestingly, the mass of the black hole divided by the mass gap seems closely related to the Bekenstein-Hawking entropy and thereby potentially leads to a quantization of black holes. Even if mathematically trivial, this could be a potentially important step toward better understanding the potential to quantize black holes. Our focus is mainly on Schwarzschild black holes, but we also briefly discuss Reissner-Nordström black holes. It is also important that this results leads to minimal gravitational acceleration, creating a gravitational gap that could potentially eliminate dark matter.
The Effectiveness of Special Repayment Strategies in Overcoming Bad Credit at Leasing Company PT.Mega Auto Central Finance
Authors: Manik O. D. S. G. , Peong H. K.
Published: December 2024

ABSTRACT
Bad credit is a problem in non-bank financial institutions such as leasing companies, so a good strategy is needed to overcome this. One of them is the implementation of a special repayment strategy of PT Mega Auto Central Finance. This study aims to determine the effectiveness of the implementation of a special repayment strategy in overcoming bad credit at the leasing company PT Mega Auto Central Finance (PT MACF). The approach used in this research is qualitative which produces descriptive data in the form of written words from people and observable behavior. The stages of this research method consist of information collection, reduction, and selection. The research location is located at PT Mega Auto Central Finance Sidikalang. Informants consisted of the heads of posts, administration, collector coordinators, and implementers of the special repayment program. Data collection techniques used interviews (primary) to 13 employees, observation, and secondary data (books and journals). The results of the study said that this company had a high level of bad debts on motorcycle loans. After the implementation of the special repayment strategy, the bad debt rate decreased from previous years. In November 2023, the company's bad debts of 29% were lower than before the implementation of the special repayment strategy in 2020 of 36%.
An Examination of The Role of Psychological Empowerment on Entrepreneurial Success: Evidence of Women Entrepreneurs in Semarang City
Authors: Sugiyanto Eviatiwi Kusumaningtyas , Wijayanti Ratna , Damajanti Anita , Arif Muhammad , Shujahat Ali
Published: December 2024

Purpose – This study aims to review empirical data on the effect of empowerment on performance at the individual level. It investigates the aspects of empowerment and how they affect a female entrepreneur’s ability to succeed. 
Methodology – We collected 96 female entrepreneurs in Semarang City participated in this study. Data was gathered using a Google form link questionnaire. The data was analyzed using the WrapPLS 8.0 software and the structural equation modelling (SEM) technique.
Findings – The findings showed that women’s success as entrepreneurs is influenced by all three aspects of psychological empowerment: self-determination, competence, and impact. However, the meaning dimension does not affect women’s entrepreneurial success.
Originality – Based on the body of knowledge from previous research, there is a population gap. The originality of this research is to consider the object that has not been studied in previous studies, that is, women entrepreneurs.
Characterization and genomic analysis of Salmonella Abortusequi phage, vB_SalP_LDDK01, and its biocontrol application in donkey meat
Authors: Cao Shengliang , Kong Xinyu , Liu Yixuan , Wang Zhiwei , Zhang Zhi , Lei Xiaojing , Li Pan , Wang Liting , Yang Fan , Liu Shiyang , Li Rongyue , Li Yubao , Feng Xiujuan , Wang Tongtong
Published: December 2024

Salmonella Abortusequi (S. Abortusequi) is the primary cause of abortions in equine animals, and can cause serious foodborne illness. Thus, effective biocontrol strategies are needed to decontaminate and control the emergence of foodborne diseases. In recent years, phages have been used as a new strategy for modulating foodborne pathogens and food safety. In this study, a new phage, vB_SalP_LDDK01, was isolated from donkey farm bedding. The data indicated that the incubation period of vB_SalP_LDDK01 was 10 min, the burst size was 378 PFU/cell, as well as a wide range of heat resistance (40-70°C) and pH stability (4-12). Furthermore, genomic analysis and electron microscopy indicated that vB_SalP_LDDK01 belongs to the Class Caudoviricetes and genus Jerseyvirus. Moreover, its genome was 42,378 bp long, encoded 57 ORFs, was double-stranded DNA with a 49.52% GC content, and lacked virulence and drug-resistant genes. In addition, how vB_SalP_LDDK01 inhibits the growth of S. Abortusequi and removes the biofilm of S. Abortusequi was assessed in a liquid broth medium, and the results showed that vB_SalP_LDDK01 inhibited the growth of S. Abortusequi for about 8 h and significantly reduced the viable bacteria abundance compared with the phage-free positive control. Further, vB_SalP_LDDK01 treated the host bacteria for 12 h and effectively destroyed the biofilm of S. Abortusequi. This study further investigated how effectively vB_SalP_LDDK01 modulates bacterial contamination in donkey meat inoculated with S. Abortusequi LCU-S-ABORT-F at 4°C and 25°C. Furthermore, after 72 h of vB_SalP_LDDK01 treatment with different multiplicity of infection (1, 0.1, 0.01, and 0.001), the bacterial contamination on the surface of donkey meat was reduced by 4.3, 3.7, 3.3, and 3.5 log10 CFU/piece at 25°C, and 4.5, 3.9, 2.8, and 2.7 log10 CFU/piece at 4°C. Whereas the phage titers at different temperatures were basically comparable to the initial titers. Overall, these results indicated that vB_SalP_LDDK01, the new phage, can serve as an effective biological agent and inhibit S. Abortusequi in donkey meat.
Examining a brief web and longitudinal app-based intervention [Wysa] for mental health support in Singapore during the COVID-19 pandemic: mixed-methods retrospective observational study
Authors: Sinha Chaitali , Dinesh Dyuthi , Heaukulani Creighton , Phang Ye Sheng
Published: December 2024

The COVID-19 pandemic in Singapore led to limited access to mental health services, resulting in increased distress among the population. This study explores the potential benefits of offering a digital mental health intervention (DMHI), Wysa, as a brief and longitudinal intervention as part of the mindline.sg initiative launched by the MOH Office for Healthcare Transformation in Singapore. The paper aims to (i) Evaluate the engagement and retention of Singaporean users across the brief intervention on the mindline.sg website and the longitudinal app version of Wysa; (ii) Examine the types of negative thoughts and challenges managed during the pandemic; and (iii) Assess the impact of the conversational agent (CA) in supporting cognitive restructuring across attributional styles and cognitive patterns. A retrospective observational design with a mixed-methods approach was utilized. Website users (N = 69,055) and app users (N = 4,103) from September 1, 2020, to July 25, 2022, were included in the study. Engagement and retention were evaluated through usage data, and T-tests were used to compare engagement and retention between the app and website. A thematic analysis assessed the types of negative thoughts and the success of cognitive restructuring. Logistic regression was used to estimate the likelihood of restructuring based on negative thought type and attributional style. Users who used the longitudinal intervention after first using a brief intervention demonstrated significantly higher engagement and retention (P < 0.001). In user ratings received for mindline.sg (n = 8,959), 83.03% rated the app 3 or higher (out of 5) on helpfulness. 91.6% of the users (n = 862) who attempted cognitive restructuring (n = 790) on the app successfully reframed a thought. A single conversation with Wysa was also significantly associated with the ability to restructure future-oriented negative thoughts (P < 0.001) and internal, stable and global (P < 0.001) negative thoughts, while other attributional styles required more intervention. Psychosocial challenges managed by users during COVID-19 were also documented through negative thoughts mentioned within the CA. The findings demonstrate that brief interventions can facilitate enhanced engagement with DMHIs and that digital interventions can successfully facilitate cognitive restructuring and improve mental health outcomes. The study provides useful inputs to guide the development of DMHIs and improve their effectiveness.
Triglycerides to apolipoprotein A1 ratio: an effective insulin resistance-associated index in identifying metabolic dysfunction-associated fatty liver disease in type 2 diabetes mellitus
Authors: Wang Wei , Chen Yang , Tu Mei , Chen Hang Ju
Published: December 2024

Background

The triglycerides to Apolipoprotein A1 ratio (TG/APOA1) holds promise to be a more valuable index of insulin resistance for the diagnosis of metabolic dysfunction-associated fatty liver disease (MAFLD) in type 2 diabetes mellitus (T2DM). This study aims to evaluate the correlation between TG/APOA1 and MAFLD, as well as compare the efficacy of TG/APOA1 with triglycerides to high-density lipoprotein cholesterol ratio (TG/HDL-c) and triglyceride-glucose (TyG) index in identifying MAFLD among individuals with T2DM.

Method

This study consecutively recruited 779 individuals with T2DM for the investigation. The unenhanced abdominal CT scans were conducted to measure CT liver-spleen attenuation measurement (CTL-S). The CTL-S less than 1.0 and without other liver comorbidities were considered to be MAFLD. The binomial logistic regression analysis and restricted cubic spines (RCS) were employed to evaluate the association between TG/APOA1 and MAFLD. The receiver operating characteristic (ROC) curve analysis was performed to compare the efficacy of TG/APOA1 with TG/HDL-c and TyG index identifying MAFLD.

Results

The TG/APOA1 exhibited a substantial increase in the MAFLD group (P<0.05). Even after adjustments for potential confounding factors, TG/APOA1 exhibited significant associations with nonalcoholic fatty liver disease fibrosis score (β=0.266, P<0.001), fibrosis-4 index (β=0.123, P=0.029), aspartate aminotransferase-to-platelet ratio index (β=0.113, P=0.037), and CTL-S (β=-0.225, P<0.001). Meanwhile, TG/APOA1 contributed to an independent variable for MAFLD, the odds ratio with a 95% CI was 2.092 (1.840-2.380) in the total population, 2.123 (1.810-2.511) in men, and 2.162 (1.824-2.587) in women. Additionally, the results also revealed a nonlinear association between elevated TG/APOA1 and higher MAFLD risk according to the RCS analysis whether in the total population, men, or women (P for nonlinearity and overall <0.001). Furthermore, TG/APOA1 had higher AUC level compared to TG/HDL-c and TyG index in the total population (0.769 vs 0.742, P=0.025; 0.769 vs 0.694, P < 0.001), men (0.776 vs 0.744, P=0.044; 0.776 vs 0.709, P < 0.001), and women (0.762 vs 0.728, P=0.041; 0.762 vs 0.674, P < 0.001).

Conclusion

TG/APOA1 serves as an effective index of insulin resistance in identifying MAFLD, offering advantages in the screening of MAFLD in T2DM.
The incidences of postoperative hypoparathyroidism during thyroid surgery with ipsilateral central lymph node dissection for papillary thyroid carcinoma were close to that during thyroid surgery for benign thyroid diseases necessitating surgical intervention: a retrospective study
Authors: Wang Bin , Zhu Chun-Rong , Fei Yuan , ShanZhou Qiyue , Liu Hong , Yao Xin-Min , Wu Jian
Published: December 2024

Objective

This study aimed to assess the degree of effect of central lymph node dissection on postoperative hypoparathyroidism incidence.

Methods

The incidence of postoperative hypoparathyroidism was compared between patients receiving thyroidectomy with central neck dissection for papillary thyroid carcinoma and those undergoing thyroidectomy for benign thyroid diseases (thyroid follicular adenoma and/or nodular goiter) necessitating surgical intervention.

Results

The incidence of postoperative hypoparathyroidism was not significantly different between the groups of lobe thyroidectomy for benign thyroid diseases and lobe thyroidectomy with ipsilateral central lymph node dissection for papillary thyroid carcinoma (immediate: 9.2% vs 3.0%, P = 0.157; protracted: 4.6% vs 0%, P = 0.06; permanent: 0% vs 0%). Similarly, there was no significant difference in the postoperative hypoparathyroidism incidence between total thyroidectomy for benign thyroid diseases and total thyroidectomy with ipsilateral central lymph node dissection for papillary thyroid carcinoma (immediate: 25.0% vs 33.8%, P = 0.12; protracted: 4.5% vs 5.3%, P = 0.99; permanent: 1.1% vs 0.9%, P > 0.99).

Conclusion

While the rates of postoperative hypoparathyroidism during thyroid surgery with ipsilateral central lymph node dissection may be slightly elevated compared to surgery without it for papillary thyroid carcinoma, they remained akin to those observed during surgery for benign thyroid diseases that need surgical management.