bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH PERAN TENAGA KESEHATAN TEHADAP PENCEGAHAN PENYAKIT MENULAR SEKSUAL
Authors: Maesaroh Maesaroh
Published: March 2022

Penyakit Menular Seksual (PMS) merupakan penyakit yang ditularkan melalui hubungan seksual, baik secara vaginal, oral, ataupun anus dengan seseorang yang sebelumnya sudah terinfeksi. Tenaga kesehatan memiliki pengetahuan dan keterampilan melalui pendidikan di bidang kesehatan untuk melakukan upaya kesehatan untuk dapat mencegah dan memberikan promosi kesehatan terkait kesehatan reproduksi terutama dalam pencegahan penyakit menular seksual. Sehingga penelitian ini bertujuan untuk mengetahui peran tenaga kesehatan terhadap pencegahan PMS. Penelitian ini adalah penelitian kuantitatif, dengan menggunakan pendekatan “Cross Sectional” atau potong lintang. Populasi dalam penelitian ini adalah wanita yang telah menikah berusia 20-45 tahun di wilayah Desa Ciharalang Kecamatan Cijeungjing Kabupaten Ciamis sebanyak 164 orang, sedangkan sampel yang diteliti sebanyak 45 orang. Hasil penelitian menunjukkan terdapat pengaruh antara peran tenaga kesehatan terhadap pencegahan penyakit menular seksual karena hasil uji statistik dengan menggunakan Uji Chi Square, dengan derajat kemaknaan 0,05 diperoleh ρ value 0,001 > α dan chi square (χ2) tabel (11,414 > 3,841). Diharapkan dalam melakukan kegiatan promosi kesehatan sebaiknya menggunakan alat peraga seperti brosur atau leafleat, sehingga responden akan lebih paham terkait peningkatan kesehatan reproduksi dan pencegahan PMS.Kata Kunci: tenaga kesehatan, penyakit menular seksual Abstract Sexually Transmitted Diseases (STDs) are diseases that are transmitted through sexual contact, whether vaginal, oral, or anus with someone who was previously infected. Health workers have the knowledge and skills through education in the health sector to make health efforts to prevent and provide health promotion related to reproductive health, especially in the prevention of sexually transmitted diseases. So this study aims to determine the role of health workers in preventing STDs. This research is a quantitative study, using a "cross sectional" approach. The population in this study were 164 married women aged 20-45 years in Ciharalang Village, Cijeungjing District, Ciamis Regency, while the sample studied was 45 people. The results showed that there was an influence between the role of health workers on the prevention of sexually transmitted diseases because the results of statistical tests using the Chi Square test, with a significance degree of 0.05 obtained ρ value 0.001> α and chi square (χ2) table (11.414> 3.841). It is hoped that in carrying out health promotion activities, it is best to use props such as brochures or leaflets, so that respondents will understand more about improving reproductive health and preventing STDs.Keywords: health workers, sexually transmitted diseases
PENGARUH BACK MASSAGE TERAPI TERHADAP PENURUNAN NYERI REUMATIK PADA LANSIA
Authors: Abdillah Awaludin Jahid , Suwandi Maryam Fitria
Published: March 2022

Back Massage adalah salah satu tehnik memberikan tindakan masase pada punggung selama 10-15 menit. Usapan dengan lotion/balsem memberikan sensasi hangat dengan mengakibatkan dilatasi pada pembuluh darah lokal. Penelitian ini bertujuan untuk mengetahui pengaruh back massage terhadap intensitas nyeri reumatik pada lansia. Penelitian ini merupakan ekperiment pra experimental dengan rancangan one group pretest-postest design. Jumlah populasi yang diberi perlakuan seluruh lansia sebanyak 25 responden dengan teknik total sampling. Pengumpulan data dilakukan melalui lembar observasi menggunakan skala nyeri numerik. dianalisis dengan Wilcoxon Matchead Pairs p-value  Hasil penelitian menunjukan intensitas skala nyeri pasien sebelum dilakukan back massage berupa nyeri sedang dan setelah perlakuan terjadi perubahan intensitas nyeri menjadi nyeri ringan. Hasil uji statistik Wilcoxon Signed Rank Test diperoleh p-value = 0.000, ada pengaruh back massage terhadap nyeri reumatik pada lansia. Hasil penelitian diharapkan menjadi pertimbangan dalam penerapan terapi komplementer dalam keperawatan khususnya terapi back massage dalam menurunkan nyeri pada lansia dengan rematikKata Kunci: Back Massage, Nyeri, Reumatik, Lansia  AbstractBack Massage is one of the techniques to provide massage action on the back for 10-15 minutes. The lotion / balm rub provides a warm sensation by dilating the local blood vessels. This study aims to determine the effect of back massage on the intensity of rheumatic pain in the elderly. This research is a pre experimental experiment with one group pretest-postest design. The total population treated by all elderly were 25 respondents with a total sampling technique. The data were collected through observation sheets using a numerical pain scale. analyzed by Wilcoxon Matchead Pairs p-value ≤0.05. The results showed the intensity of the patient's pain scale before doing back massage in the form of moderate pain and after treatment there was a change in pain intensity to mild pain. The results of the Wilcoxon Signed Rank Test statistical test obtained p-value = 0.000 < (a) then Ha is accepted, there is an effect of back massage on rheumatic pain in the elderly. The result are expected to be considered in the application of complementary therapy in nursing practice, especially back massage therapy in reducing pain in the elderly with rheumatism.Keywords: Back Massage, Pain, Rheumatism, Elderly
HUBUNGAN PENGETAHUAN TENTANG COVID-19 DENGAN PERILAKU ADAPTASI KEBIASAAN BARU
Authors: Susiani Ani , Rani Manggar
Published: March 2022

AbstrakWHO telah menetapkan penyakit Covid-19 sebagai Public Healty Emergency of International Concern akibat dampak yang ditimbulkannya. Penularan penyakit Covid-19 yang mudah dan cepat telah meningkatkan jumlah kasus dengan angka kematian yang tinggi pada penderitanya. Upaya yang dapat dilakukan untuk mengendalikan penyakit tersebut adalah dengan meningkatkan pencegahan terhadap penularan penyakit diantaranya melalui penerapan perilaku adaptasi kebiasaan baru oleh masyarakat. Penelitian ini bertujuan untuk mengetahui hubungan antara pengetahuan tentang penyakit Covid-19 dengan perilaku adaptasi kebiasaan baru pada anggota kelompok Pengajian Nurul Hikmah dan Al Hidayah di wilayah kerja Puskesmas Margadadi Kabupaten Indramayu. Penelitian ini merupakan penelitian kuantitatif analitik dengan menggunakan pendekatan cross sectional. Populasi penelitian adalah anggota kelompok pengajian Nurul Hikmah dan Al Hidayah yang berjumlah 94 orang. Pemilihan sampel dilakukan dengan teknik total sampling. Hasil penelitian menunjukkan adanya hubungan yang signifikan antara pengetahuan responden tentang Covid-19 dengan perilaku adaptasi kebiasaan baru dengan nilai p value = 0,000 (p < 0,000). Penulis menyarankan kepada Dinas Kesehatan untuk meningkatkan pelaksanaan penyuluhan mengenai Covid-19 baik secara langsung maupun melalui pelatihan kader tanggap Covid-19.Kata kunci: pengetahuan, perilaku AKB, Covid-19  Abstract WHO has designated Covid-19 as a Public Health Emergency of International Concern due to the effects it causes. The easy and fast transmission of the Covid-19 disease has increased the number of cases with a high mortality rate in sufferers. Efforts that can be made to control the disease are to increase the prevention of disease transmission, including through the application of new habitual adaptation behaviors by the community. This study aims to determine the relationship between knowledge about Covid-19 and new habitual adaptation behavior of members of the Nurul Hikmah and Al Hidayah study groups in the working area of Puskesmas Margadadi, Indramayu Regency. This research is a quantitative analytic study using a cross sectional approach. The study population was the members of the muslim forum of  Nurul Hikmah and Al Hidayah, totaling 94 people. The sample selection is done by using total sampling technique. The results showed that there was a significant relationship between respondents' knowledge about Covid-19 and new habitual adaptation behavior with p value = 0.000 (p <0.000). The author advises the Health Office to increase the implementation of health education about Covid-19 both directly and through training for Covid-19 response cadres.Keywords: knowledge, behavior of AKB, Covid-19
PENGARUH MOBILISASI DINI TERHADAP PROSES INVOLUSI UTERI
Authors: Hikhmat Rokhmatul , Lestari Sri , Dewi Ning Puspita
Published: March 2022

Pelaksanaan tindakan mobilisasi dini pada pasien post sectio caesaria rata-rata baru mencapai 23,3% dari seluruh persalinan di rumah sakit Karya Husada, padahal mobilisasi dini merupakan tindakan yang sangat efektif guna mencegah komplikasi pada pasien post sectio caesaria. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian mobilisasi dini terhadap proses involusi uteri pada pasien post sectio saesaria. Jenis penelitian ini adalah Quasi Eksperimen atau eksperimen semu. instrumen yang digunakan adalah kuesioner dengan pertanyaan tertutup. Jumlah responden 30 responden dalam kelompok kontrol 15 responden dan kelompok intervensi 15 responden. Hasil penelitian bahwa nilai rata-rata penurunan TFU pada kelompok kontrol adalah paling banyak pada skala 0,5 cm yaitu sebanyak 5 orang (33,3%). pada  responden kelompok intervensi paling banyak pada nilai 2,5 – 3 cm yaitu sebanyak 8 orang (73,3%). Uji statistik menggunakan uji T-Test diketahui bahwa terdapat perbedaan yang bermakna antara rata - rata penurunan TFU kelompok intervensi dengan kelompok kontrol pada pasien post sectio caesaria, dimana nilai signifikansi 0,023 < α 0,05. Saran dari penelitian ini bagi rumah sakit agar pelaksanaan tindakan  pemberian mobilisasi dini pada pasien post sectio caesaria lebih ditingkatkan guna menjamin kualitas asuhan keperawatanKata Kunci: Mobilisasi Dini, Involusi Uteri, Post Sectio Caesaria ABSTRACTThe implementation of early mobilization in post sectio caesaria patients only reached 23.3% of all deliveries at the Karya Husada hospital, even though early mobilization is a very effective measure to prevent complications in post sectio caesaria patients. This study aims to determine the effect of early mobilization on the process of uterine involution in post sectio saesaria patients. The type of research is Quasy Experiment or quasi-experiment. The instrument used was a questionnaire with closed questions. The number of respondents was 30 respondents in the control group 15 respondents and the intervention group 15 respondents. The results showed that the average TFU reduction in the control group was the most on a scale of 0.5 cm, namely 5 people (33.3%). The most respondents in the intervention group were at a value of 2.5 - 3 cm, namely as many as 8 people (73.3%). Statistical test using the T-Test shows that there is a significant difference between the average reduction in TFU of the intervention group and the control group in post sectio caesaria patients, where the significance value is 0.023 <α 0.05.Suggestions from this study for hospitals so that the implementation of early mobilization in post sectio caesaria patients is further improved in order to ensure the quality of nursing careKeywords: Early Mobilization, Uterine Involution, Post Sectio Caesaria
Pediyatrik Hastada Nedeni Bilinmeyen Ateş
Authors: AKYILDIZ Mustafa Yasir , DİNDAR DEMİRAY Emine Kübra
Published: March 2022

Pediyatrik hastalarda ateş sık karşılaşılan bir klinik sendromdur. Nedeni bilinmeyen ateşin ise erişkinde net tanımlaması olmasına rağmen, çocuk yaş grubunda bu tanım konusunda fikir birliği yoktur. Çalışmalar arasında farklılıklar mevcut olup, bu konudaki literatür de sınırlıdır. Biz de bu çalışmada mevcut literatürü çocuk yaş grubunda nedeni bilinmeyen ateş açısından derlemeyi amaçladık.
EVALUATION OF THE IMPACTS OF AUTONOMOUS VEHICLES ON THE MOBILITY OF USER GROUPS BY USING AGENT-BASED SIMULATION
Authors: Hamadneh Jamil , Esztergar-Kiss Domokos
Published: March 2022

An agent-based transport simulation model is used to examine the impacts of Autonomous Vehicles (AVs) on the mobility of certain groups of people. In the state of the art, it has been found that the researchers primarily have simulation studies focusing on the impacts of AVs on people regardless of certain groups. However, this study focuses on assessing the impacts of AVs on different groups of users, where each group is affected variously by the introduction of different penetration levels of AVs into the market. The Multi-Agent Transport Simulation (MATSim) software, which applies the co-evolutionary algorithm and provides a framework to carry out large-scale agent-based transport simulations, is used as a tool for conducting the simulations. In addition to the simulation of all travellers, 3 groups of users are selected as potential users of AVs, as follow: (1) long commuters with high-income, (2) elderly people who are retired, and (3) part-time workers. Budapest (Hungary) is examined in a case study, where the daily activity plans of the households are provided. Initially, the existing daily activity plans (i.e., the existing condition) of each group are simulated and assessed before the introduction of AVs into the market. After that, the AVs are inserted into the road network, where different fleet sizes of AVs are applied based on the demand of each group. The marginal utility of the travel time spent in case of a transport mode, the AV fleet size, and the cost of the travel are the key variables that determine the use of a transport mode. The key variables are set based on the characteristics of the case study (i.e., demand) and the AVs. The results of the simulations suggest that the AVs have different degrees of influences on certain groups as demonstrated in the occurred changes on the modal share. The value of changes depends on the Value of Travel Time (VOT) of people and the used fleet size of AVs. Moreover, the influence of the traveller’s characteristics on the AVs is manifested, such as different values of fleet utilization. Furthermore, the study demonstrates that an increase in the fleet size of AVs beyond 10% of the demand does not significantly raise the modal share of AVs. The outcome of this paper might be used by decision-makers to define the shape of the AVs’ use and those groups who are interested in using AVs.
The Second Catalog of Interplanetary Network Localizations of Konus Short-duration Gamma-Ray Bursts
Authors: Svinkin D. S. , Hurley K. , Ridnaia A. V. , Lysenko A. L. , Frederiks D. D. , Golenetskii S. V. , Tsvetkova A. E. , Ulanov M. V. , Kokomov A. , Cline T. L. , Mitrofanov I. , Golovin D. , Kozyrev A. , Litvak M. , Sanin A. , Goldstein A. , Briggs M. S. , Wilson-Hodge C. , Burns E. , von Kienlin A. , Zhang X.-L. , Rau A. , Savchenko V. , Bozzo E. , Ferrigno C. , Barthelmy S. , Cummings J. , Krimm H. , Palmer D. M. , Tohuvavohu A. , Yamaoka K. , Ohno M. , Fukazawa Y. , Hanabata Y. , Takahashi T. , Tashiro M. , Terada Y. , Murakami T. , Makishima K. , Boynton W. , Fellows C. W. , Harshman K. P. , Enos H. , Starr R. , Goldsten J. , Gold R. , Ursi A. , Tavani M. , Bulgarelli A. , Casentini C. , Del Monte E. , Evangelista Y. , Galli M. , Longo F. , Marisaldi M. , Parmiggiani N. , Pittori C. , Romani M. , Verrecchia F. , Smith D. M. , Hajdas W. , Xiao S. , Cai C. , Yi Q. B. , Zhang Y. Q. , Xiong S. L. , Li X. B. , Huang Y. , Li C. K. , Zhang S. N. , Song L. M. , Liu C. Z. , Li X. Q. , Peng W. X. , Martinez-Castellanos I.
Published: March 2022

We present the catalog of InterPlanetary Network (IPN) localizations for 199 short-duration gamma-ray bursts (sGRBs) detected by the Konus-Wind (KW) experiment between 2011 January 1 and 2021 August 31, which extends the initial sample of IPN-localized KW sGRBs to 495 events. We present the most comprehensive IPN localization data on these events, including probability sky maps in Hierarchical Equal Area isoLatitude Pixelization format.
MaxEnt model-based prediction of potential distributions of Parnassia wightiana (Celastraceae) in China
Authors: Dai Xiaosong , Wu Wei , Ji Ling , Tian Shuang , Yang Bo , Guan Bicai , Wu Ding
Published: March 2022

The maximum entropy (MaxEnt) model for predicting the potential suitable habitat of species has been commonly employed in many ecological and biological applications by using presence-only occurrence records along with associated environmental factors. Parnassia wightiana, a perennial herb, is a cold-adapted plant distributed across three diversity hotspots in China, including the Hengduan Range, Central China and the Lingnan region. The MaxEnt model was used to simulate the historic, current and future distribution trends of P. wightiana, as well as to analyse its distribution pattern in each historical period and explore the causes of species distribution changes. The results of our analysis indicated that annual precipitation, annual temperature range and mean temperature of the warmest quarter were the key bioclimatic variables affecting the distribution of P. wightiana. Most temperate species retracted into smaller refugial areas during glacial periods and experienced range expansion during interglacial periods. Possible refugia of the species were inferred to be located in the Hengduan Range and Qinling Regions.
Cytotoxic activities of ethanolic crude extracts from fruiting bodies of bamboo mushrooms (Dictyophora spp.) against cholangiocarcinoma cells
Authors: Chantree Pathanin , Chumkiew Sirilak , Jamklang Mantana , Martviset Pongsakorn
Published: March 2022

Introduction: Cholangiocarcinoma (CCA) is a highly progressive tumor. The standard chemotherapy varies in its effectiveness, with generally low efficacy. So, the discovery of novel chemotherapy is still required. The objective of this preliminary study was to determine the cytotoxic effects induced by three kinds of bamboo mushrooms (Dictyophora indusiata or Chinese bamboo mushroom; Ch-DTP, Short skirt bamboo mushroom (Thai isolate); Th-DTP, and orange skirt bamboo mushroom; Or-DTP) on CCA cells.

Materials and methods: CCA cell lines, including CL-6, HuCCT1, HuH28, and OUMS normal fibroblast cells, were treated with various concentrations of DTP extracts. The MTT assay was used to determine cytotoxicity, and cell morphology was observed by using phase-contrast microscopy.

Results and discussion: The results suggested that Ch-DTP effectively killed all three CCA cell lines in both low (0.3 mg/mL) and high (0.6 mg/mL) doses, but Th-DTP and Or-DTP had significantly reduced cell viability only at high doses (p<0.001). Ch-DTP had the best effect by showing a response of more than 50% at a concentration of 0.3 mg/mL. Th-DTP had moderate effects at a concentration of lower than 0.6 mg/mL but worthwhile at higher concentrations, whereas Or-DTP had limited effects at concentrations of 0.4 mg/mL and downward, although the effects were significantly increased in the higher concentration range. Morphology of the Ch-DTP treated cells was greatly transformed both at low and high doses, but Th-DTP and Or-DTP showed definite alteration only at high doses. The morphological changes revealed apoptotic induction. In OUMS cells, no effects were recognized with any of the three DTPs.

Conclusion: This study indicated that DTP extracts could induce cytotoxicity in cholangiocarcinoma, with a high potential of being an effective therapeutic agent.
A new genus of minute stingless bees from Southeast Asia (Hymenoptera, Apidae)
Authors: Engel Michael S. , Nguyen Lien Thi Phuong , Tran Ngat Thi , Truong Tuan Anh , Herrera Motta Andrés F.
Published: March 2022

A new genus of minute stingless bees (Meliponini: Hypotrigonina) is described from Southeast Asia.EbaiotrigonaEngel & Nguyen,gen. nov., is based on the type speciesLisotrigona carpenteriEngel, recorded from Vietnam, Thailand, Laos, Cambodia, and southern China. The species was previously considered an enigmatic member ofLisotrigonaMoure, but is removed to a new genus based on its unique male terminalia that differs considerably from that ofLisotrigonaand instead shares resemblances withAustroplebeiaMoure, and the presence of yellow maculation (also similar to that ofAustroplebeia). It is possible thatEbaiotrigonais the extant sister group ofAustroplebeia, but this requires confirmation by future phylogenetic analyses. Based on available biological observations,Ebaiotrigona carpentericould not be confirmed as lachryphagous as is well documented from the tear-drinking species ofLisotrigonaandPariotrigonaMoure.
Obstétrique, (non)violence et féminisme
Authors: Topçu Sezin
Published: March 2022

De nombreux problèmes au cœur de l’actuelle controverse sur les violences obstétricales ont déjà été mis sur la table dans la France des années 1970. Cet article met le projecteur sur les critiques forgées et les expériences alternatives lancées durant cette période pour faire face à l’expansion des doctrines, normes et pratiques médicales jugées mal-traitantes. Notre objectif est de décrypter en particulier la manière dont le concept de non-violence est alors pensé, théorisé et mis en pratique, les dynamiques qu’il a fait émerger, et les tensions multiples et variées qu’il a engendrées, au sein notamment du mouvement féministe.
Human biomonitoring of multiple mycotoxins in hair: first large-scale pilot study
Authors: Narváez A. , Rodríguez-Carrasco Y. , Ritieni A. , Mañes J.
Published: March 2022

Human biomonitoring (HBM) represents the most accurate approach for assessing the exposure to mycotoxins, but traditional matrices fail to provide information about long-term exposure due to the rapid excretion rates and short half-lives of mycotoxins. Hair emerges as a promising matrix considering that contaminants can form stable links with hair components, such as keratins and melanin. Hence, the aim of the present study was to monitor the presence of up to ten mycotoxins (aflatoxins andFusarium mycotoxins) in human hair samples (n=100) through a high-performance liquid chromatography coupled to Q-TOF high resolution mass spectrometry. A prevalence of 43% at concentrations ranging from 2.7 to 106.1 ng/g was observed, being enniatins and aflatoxin B1 the most prevalent compounds. Co-occurrence of up to three mycotoxins was observed in 42% of the positive samples. Retrospective untargeted analysis of hair samples tentatively identified up to 128 mycotoxins and related metabolites. These results confirm the accumulation of toxicologically relevant mycotoxins in hair matrix, thus standing as a suitable matrix for assessing long-term exposure.
Promoting Child Health Equity Through Medicaid Innovation
Authors: Peltz Alon , Wong Charlene A. , Garg Arvin
Published: March 2022

Black, Latino/a/e, American Indian, and Alaska Native children often receive lower quality health care than White children. As the predominant health insurer for medically underserved populations, Medicaid plays a critical role in advancing socioeconomic and racial health equity. In this article, we focus on structural barriers to health equity in the Medicaid program and potential steps for improving long-standing socioeconomic and racial health inequities through programmatic innovation. We identify opportunities for expanding care models for holistically addressing the social determinants of health, aligning clinical care delivery around health equity principles, diversifying the clinical workforce, and promoting meaningful and consistent provider participation in Medicaid. Practitioners and policy makers can start to undertake many of these steps today to set the stage for more sweeping reforms that can help achieve national health equity goals for children.

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Pediatr Ann
. 2022;51(3):e118–e122.]
Healthy Eating and Diets: Fad or Rad?
Authors: Liu Amy
Published: March 2022

One of the top chronic diseases in the United States is pediatric obesity. As such, many pediatricians will have conversations with patients and families regarding the health effects of this disease process. This article will provide a broad overview of many of the popular diets as well as evidence for their effectiveness. Lastly, recommendations for healthy eating and nutritional counseling with patients and families will be discussed.

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Pediatr Ann
. 2022;51(3):e88–e92.]
The RET gene encodes RET protein, which triggers intracellular signaling pathways for enteric neurogenesis, and RET mutation results in Hirschsprung's disease
Authors: Bhattarai Chacchu ,   Department of Anatomy, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Karnataka, 576104, India, Poudel Phanindra Prasad , Ghosh Arnab , Kalthur Sneha Guruprasad ,   Department of Anatomy, Manipal College of Medical Sciences, Pokhara, Nepal,   Department of Pathology, Manipal College of Medical Sciences, Pokhara, Nepal
Published: March 2022

Enteric neurons and ganglia are derived from vagal and sacral neural crest cells, which undergo migration from the neural tube to the gut wall. In the gut wall, they first undergo rostrocaudal migration followed by migration from the superficial to deep layers. After migration, they proliferate and differentiate into the enteric plexus. Expression of the Rearranged During Transfection (RET) gene and its protein RET plays a crucial role in the formation of enteric neurons. This review describes the molecular mechanism by which the RET gene and the RET protein influence the development of enteric neurons. Vagal neural crest cells give rise to enteric neurons and glia of the foregut and midgut while sacral neural crest cells give rise to neurons of the hindgut. Interaction of RET protein with its ligands (glial cell derived neurotrophic factor (GDNF), neurturin (NRTN), and artemin (ARTN)) and its co-receptors (GDNF receptor alpha proteins (GFRα1-4)) activates the Phosphoinositide-3-kinase-protein kinase B (PI3K-PKB/AKT), RAS mitogen-activated protein kinase (RAS/MAPK) and phospholipase Cγ (PLCγ) signaling pathways, which control the survival, migration, proliferation, differentiation, and maturation of the vagal and sacral neural crest cells into enteric neurons. Abnormalities of the RET gene result in Hirschsprung's disease.
Odločevalna vprašanja in tipi odgovorov nanje v češčini v primerjavi s slovenščino
Authors: Škvorc Ines
Published: March 2022

Odločevalna vprašanja in odgovori nanje imajo tako v češčini kot v slovenščini podobno skladenjsko in leksikalno zgradbo. Razlike med češkimi in slovenskimi odločevalnimi vprašanji so očitne predvsem na funkcijski in stilni ravni, pri odgovorih pa tudi na ravni leksikalno-skladenjskih uresničitev. V prispevku so sistematično razdelani različni načini uresničitve povedka pri odločevalnih vprašanjih in odgovorih nanje v češčini in slovenščini ter primerjana njihova leksikalna struktura v obeh jezikih.
Pretender ser lo que fue: Domingo Martínez y la restauración de las pinturas murales de la Giralda
Authors: Escuredo Elena , Muñoz Nieto Enrique
Published: March 2022

En el siglo XVIII, la decoración mural que Luis de Vargas (1566) había realizado en los arcos ciegos de la Giralda y en los medios punto de su cara norte debía encontrarse en un mal estado de conservación. Es por ello que el Cabildo ca­tedralicio mostró una clara intención de retocarla, intentando paliar los estragos del paso del tiempo y de la climatología. Son diversos los autos capitulares que dejan constancia de la voluntad de devolver el esplendor a la torre. Consideradas las distintas posibilidades de intervención, sería el pintor Domingo Martínez el designado para mejorar los frescos antes de que se perdieran para siempre, algo que, sin embargo, ocurriría décadas más tarde.
Un método para establecer la viabilidad de las poblaciones de la araña trampera Amblyocarenum en áreas urbanas: un estudio piloto
Authors: Calatayud-Mascarell Arnau , Migueles-Miralles Luna
Published: March 2022

Amblyocarenum walckenaeri (Lucas, 1846) (Araneae: Mygalomorphae: Nemesiidae) se encuentra en varias zonas urbanas de La Safor (Valencia, España). Aquí, presentamos un método que podría exponer el efecto perturbador de la rápida expansión urbana en poblaciones de arañas tramperas: contando las clases de edades de una población como indicador de su viabilidad. Nuestros resultados muestran que la mayoría de las poblaciones urbanas muestreadas no presenta crías. Esto sugiere que Amblyocarenum existe en dichas zonas urbanas como remanentes; poblaciones envejecidas que presentan dificultad a la hora de reclutar nuevas generaciones de ejemplares, tornándose inviables.
Localización y confirmación de la existencia del holotipo de Plagionotus andreui Fuente, 1908 (Coleoptera: Cerambycidae)
Authors: Fernández-Carrillo‍ Enrique , Fernández-Carrillo‍ José Luis
Published: March 2022

Se localiza y se confirma la existencia del holotipo de Plagionotus andreui Fuente 1908, en la colección Fuente. Se realiza un resumen de la historia nomenclatural y taxonómica de la especie hasta el presente.
Human Intelligence Cultivation with the 2CG® Poetry Machine
Authors: Merl Christina
Published: March 2022

Acquiring pure fact-based knowledge is no longer sufficient when it comes to dealing with increasingly complex realities in the machine age, such as the degrowth economy, climate change and global health crises. 21st century learners who want to interact with the world in a constructive way need to cultivate (human) capabilities, develop relevant practical skills and acquire relational knowledge, which implies that they can apply factual knowledge in diverse contexts so as to solve complex problems. The present paper aims to demonstrate how the 2CG® Poetry Machine, a hybrid coaching tool that makes use of artistic impulses, can support learners across cultural, hierarchical and disciplinary boundaries in developing future skills and generating new ideas. The focus is on communication skills, critical thinking skills, creativity and imagination, collaborative skills and ICT literacy. Practice examples are given to show how the 2CG® Poetry Machine uses impulses from poetry, puppetry, literature, theater, photography, dance and music to enable learners to connect with their creative power, improve their skills and generate new ideas in Lab 21, a hybrid hyper-structure for learning, sharing and exploring new ways of thinking and doing.
Combining and Balancing Project-Based and Blended Learning in Education
Authors: Knoblauch Christoph
Published: March 2022

This paper discusses evaluation findings from project-based and blended learning courses in the higher education sector and beyond. The multi-method studies focus on learners’ attitudes, practices and preferences towards project-based and blended learning. The evaluated courses were developed and taught in the context of teacher training programs at Ludwigsburg University of Education (LUE). They aim at the planning, execution and critical reflection of individual projects carried out by the participating students in blended learning contexts. This paper presents a discussion of the structure, the blended methodology and the outcomes of the courses, combining the methods of quantitative evaluation research and qualitative interviews. By doing so, the study assesses current practice and analyses the above-mentioned courses closely and in detail. Thus, this paper discusses how students deal with a project-based and blended learning environment and how these results can be constructively implemented to improve future project-based and blended learning scenarios.
Review of Deep Transfer Learning Models for Image Classification
Authors: Karthikeyan Neelesh
Published: March 2022

With the rapid rise in urbanization, solid waste generation has increased exceedingly. This study aims to develop a Convolutional Neural Network (CNN) to classify trash into biodegradable and non-biodegradable wastes. The TrashNet dataset was utilized in this study, and image augmentation was employed to make the model more robust against translation invariance. Transfer Learning methods based on CNN have shown promising outcomes on diverse image classification problems. This paper reviews the deep learning models available with pre-trained weights in the Keras library. The performance of the models was compared, and the model based on NASNetMobile had the highest accuracy of 97%. Further, the model’s hyper-parameters were tuned, and the significance of a hyper-parameter on the model’s accuracy was studied.
Chapitre 3. Il contesto geologico e l’evoluzione quaternaria della valle del fiume Tavo e del torrente Gallero
Authors: Agostini Silvano
Published: March 2022

Il bacino idrografico del fiume Tavo e del suo affluente Gallero si estende dal versante orientale del Gran Sasso, dove scolpisce le formazioni pertinenti alla successione carbonatica ceno-mesozoica in facies di scarpata – bacino, per ampliarsi verso est nella zona collinare fino al mare Adriatico, dove il substrato è invece costituito da successioni silico clastiche (arenarie, peliti, marne, argille) a cui si intercalano – come a Montebello di Bertona – banchi di conglomerati con clasti prevalentemente calcarei. Il Quaternario è rappresentato da forme relitte, quali superfici di paleopaesaggio, depositi di versante (brecce e coltri detritiche), corpi di frana, coltri colluviali ed unità alluvionali terrazzate e sospese a quote diverse. Gli alvei attuali sono profondamente incassati all’interno dell’unità alluvionale riferita all’ultimo tardiglaciale. Sulle sommità e all’interno delle unità alluvionali terrazzate sono conservati lembi di paleosuoli. L’elevata energia di rilievo, che evidenzia un continuo e discreto tasso di sollevamento areale per tutto il Pleistocene medio e superiore, si esprime con processi di ringiovanimento e di modellamento che hanno lasciato sospesi forme e depositi depostisi in contesti morfoclimatici differenti. In particolare le associazioni di facies dei depositi clastici a margine del rilievo montano e delle unità alluvionali del Tavo e del Gallero permettono di ricostruire l’evoluzione paleogeografica, i paesaggi e gli ambienti del Pleistocene superiore.Particolare attenzione è stata posta all’analisi della selce presente nelle formazioni della successione carbonatica affioranti, nel bacino idrografico e oltre i suoi margini, sia in forma di arnioni, che di letti discontinui o in strati sottili. Grana e colori della selce, consistenza e spessore del cortice, omogeneità e qualità, assenza, presenza e spaziatura di microfratture formazioni risultano tipici della selce presente in ciascuna delle carbonatiche. Nelle unità alluvionali pleistoceniche, la selce si rinviene negli orizzonti grossolani costituiti da ghiaie, come ciottoli sia integri che spezzati, e più diffusamente in schegge minute non utilizzabili.
Chapitre 5. La vallée du Gallero au tardiglaciaire
Authors: Le Jeune Yann
Published: March 2022

Les recherches menées à Campo delle Piane ont accordé une large place à l’étude paléoenvironnementale. Les observations stratigraphiques effectuées dans la vallée du Gallero et la cartographie des dépôts sédimentaires font apparaître la présence d’un ancien cône de déjection en contexte de piémont qui s’est formé sous un régime nival. L’incision importante du Gallero (une vingtaine de mètres) est rapportée au début de l’Holocène en relation avec le changement climatique (passage d’un régime nival à pluvio-nival) conjuguée avec une forte activité tectonique classique dans la région. Les dépôts tardiglaciaires prennent donc localement la forme d’une terrasse. Leur conservation et celle des vestiges épigravettiens résultent principalement de cette incision holocène des cours d’eau et de l’érosion provoquée par l’agriculture.La séquence sédimentaire surmontant le niveau épigravettien trouvé dans le locus n° 7 (CDP 7) constitue une coupe de référence. Ce niveau se situe sur la pente d’un ancien dôme de graviers et à proximité d’un chenal qui sont des formes héritées de la morphogenèse weichselienne. Il est associé à un paléosol brun-rouge dont la conservation est liée au comblement de ce chenal.L’étude fine de cette séquence permet de reconstituer des éléments du paléoenvironnement et de la paléoclimatologie du Tardiglaciaire dans la vallée du Gallero. L’observation macroscopique et les analyses physico-chimiques des sédiments montrent l’existence de deux paléosols distincts associés à des traces d’incendies. Le paléosol supérieur, daté par le carbone 14, est attribué à l’interstade Bølling-Allerød. La corrélation du paléosol inférieur contenant les vestiges archéologiques avec un interstade précis repose sur plusieurs datations (carbone 14 et OSL) qui le placent entre 17 ka et 21.1 ka cal. BP et sur la confrontation avec des références lointaines, de portée générale (carottes de glaces polaires et marines), et des travaux plus rapprochés réalisés en Italie (Lago di Monticchio, bassin du Fucino et Apennins). Ce paléosol semble correspondre à une période d’amélioration climatique du G2sb (Greenland Interstadial 2b), antérieure au Dryas I et postérieure au Dernier Maximum Glaciaire. C’est durant cet épisode de réchauffement et dans un environnement de prairie et de pins, et en bordure d’un chenal, que s’installent les Épigravettiens de CDP 7. Après leur départ, un incendie au moins affecte cette pinède clairsemée. Ainsi, il apparaît que les environs du massif du Gran Sasso ont enregistré cette amélioration climatique de manière plus nette qu’au nord de l’Europe laissant augurer d’intéressantes perspectives d’étude sur la fin de la période glaciaire dans cette partie des Abruzzes. En conclusion, sont retracés quelques traits majeurs de l’histoire environnementale de la vallée du Gallero depuis le Dernier Glaciaire.
A Preliminary Study of Consumer Behavior From the Online Marketplace in Indonesia
Authors: Candra Sevenpri , Tulangow Conny Elmanuella , Winalda Filda Trya
Published: March 2022

The growth of online marketplace in Indonesia is increasing. By understanding consumer behavior, online marketplaces can enhance their service quality. Consumer behaviors refer to the study of customers and how they behave while decided to do the transaction. Consumer behavior can be evaluating from activity of repurchase intention, word of mouth and site revisit. The purpose of this study is to understand the impact of e-service quality, customer satisfaction and customer trust on consumer behavior of online marketplace. This study using snow-ball sampling technique and fill-in through online questionnaires to online customers in Indonesia. There are 431 respondents and analyzed by Structural Equation Modelling using Warppls 7.0 software. Customer satisfaction and customer trust affect repurchase intention and word of mouth. While site revisits are influenced by customer satisfaction. Based on this finding, online marketplace to give more attention and improving the e-service quality to increasing the customer satisfaction and customer trust.
Comparison Between Offline and Online Distribution Practices for the Insurance Industry in India
Authors: Singh Rajni Kant , Deshmukh Anand A.
Published: March 2022

Insurance has been the back bone of Indian society and economy. For India, a developing country, insurance does serve the need to a limited extent as social security practices are absent in India compared to foreign nations. Insurance has been sold mainly through traditional channels with Agency garnering major share of the pie. The study started with robust literature review, formulating the objectives to examine existing offline distribution channels for insurance and the relative significance of emerging online distribution channel for insurance. Accordingly hypothesis were promulgated for understanding difference between online and offline insurance in terms of cost and convenience, difference between economies of scale and accuracy, beneficial to customer and/or company and on the growing trend of young internet users being a high potential target market for insurance business suitable to online channel. The study further gives suggestions and recommendations for promotion of online channels and highlights its relative significance to various stakeholders.
Deep Learning Model for Enhanced Crop Identification From Landsat 8 Images
Authors: Sucithra B.  , Gladston Angelin
Published: March 2022

Deep learning is a powerful state-of-the-art technique for image processing, including remote sensing images. This paper describes a multilevel deep learning based crop type identification system that targets land cover and crop type classification from multi-temporal multisource satellite imagery. The proposed crop type identification is based on unsupervised neural network that is used for optical imagery segmentation and missing data restoration due to clouds and shadows, and an ensemble of supervised neural networks. The main part of this multilayer deep network with Self Organizing maps and atmospheric correction is an ensemble of CNNs. The proposed system is applied for crop identification using Landsat-8 time-series and implemented with different sized vector data, parcel boundary. Aided with self-organizing maps and atmospheric correction for pre-processing doing both pixel based and parcel based analysis, this proposed crop type identification system allowed us to achieve the overall classification accuracy of nearly 95% for three different time periods.
Characterization of No-Bake Phenolic-Isocyanate and Furanic Binders in Different Base Metal Casting Sands
Authors: Sotomayor Oscar E. , Anrango Jefferson , Campoverde Carlos Diaz
Published: March 2022

This paper presents test results for silica and corundum base metals casting sands. Standardized tests were carried out to understand physical and mechanical properties of the metal casting sands and molding mixtures prepared with these refractory bases. Grain distribution, grain size, grain shape classification, moisture content, pH, LOI, Weibull distribution tensile test, permeability and roughness are the properties that have been evaluated. Tensile, permeability and roughness tests are carried out with different molding mixtures changing base sand and Phenolic-isocyanate and Furanic binders. The results of the tensile test were adjusted to a Weibull distribution. Weibull modulus of each molding mixture and the strength at a probability of failure of 63% is obtained. The permeability and roughness results were subjected to ANOVA and T-Test. Regular grains contributes to increase strength of molding mixture while permeability is not affected by time and amount of binder.
Statistical Analysis on the Influence of Stack Thickness on the Tensile Property of Glass Fiber-Reinforced Polymer Laminates
Authors: Priya I. Infanta Mary , Senthil Ramalingam , Kayaroganam Palanikumar
Published: March 2022

This work investigates the tensile testing of glass fibre-reinforced polymer (GFRP) composite material and its most influencing parameter. The GFRP constitutes bi-axial glass-fibre and epoxy-matrix. The three parameters considered for the tensile test are the load, elongation, thickness, and the experiment's factorial design is L9 orthogonal array. The percentage contribution of load, extension, and thickness for stress and strain is calculated using variance (ANOVA) analysis. Optimizating parameters made using response surface method (RSM). Since the solutions arrived at by this optimization process are promising, the optimized outcomes are high load, low elongation, and high thickness. Such works are beneficial for replacing concrete slabs constructed on the roads for rainwater harvesting. In such applications, non-crimp GFR panels with openings at regular intervals may replace concrete slab structures. A mathematical response surface model for the stress and strain parameters has been formulated. The model validation is done using the Pearson product-moment coefficient.
Moderating role of turbulent environment between IT dynamic capabilities, business agility, and innovative capabilities: Empirical evidence from Sri Lanka
Authors: Ilmudeen A.
Published: March 2022

Drawing on the resource-based theory and dynamic capability theory this study examines how IT-enabled dynamic capabilities impact on business capabilities (business process agility and firm innovative capability) with moderating role of turbulent environment. The purpose of this study is to test the impact of ITenabled dynamic on business process agility and innovative capability that in turn drive firm performance under turbulent environment. This study conceptualizes that IT governance mechanism positively effect on ITDC, that in turn positively impact on business process agility and firm innovative capability to achieve firm performance. Data were collected in offline and online by using convenient and snowball sampling technique from the senior IT and business managers in Sri Lankan. Using the partial least squares (Smart PLS 3.0) hierarchical regression analysis for various model were performed. The finding from 188 senior IT and business manager’s responses from Sri Lanka reveals the strong and positive relationship in the hypothesized relationship. In contrary to the expectation, the turbulent environment’s both hypotheses (H6a and H6b) failed to show a significant moderating effect. This study adds to the existing literature and extends the managerial practice by focusing on the key constructs such as IT governance mechanism, ITDC, turbulent environment, and firm performance.
Common and Divergent Features of T Cells from Blood, Gut, and Genital Tract of Antiretroviral Therapy–Treated HIV+ Women
Authors: Xie Guorui , Moron-Lopez Sara , Siegel David A , Yin Kailin , Polos Anastasia , Cohen Jennifer , Greenblatt Ruth M , Tien Phyllis C , Lee Sulggi A , Yukl Steven A , Roan Nadia R
Published: March 2022

T cells residing in mucosal tissues play important roles in homeostasis and defense against microbial pathogens. The gut and female reproductive tract (FRT) are both tolerogenic environments, but they differ in the kinds of foreign Ags they need to tolerate. How these different environments influence the properties of their T cells is poorly understood, but important for understanding women’s health. We recruited antiretroviral therapy–suppressed women living with HIV who donated, within one visit, blood and tissue samples from the ileum, colon, rectosigmoid, endometrium, endocervix, and ectocervix. With these samples, we conducted 36-parameter cytometry by time of flight phenotyping of T cells. Although gut and FRT T cells shared features discriminating them from their blood counterparts, they also harbored features distinguishing them from one another. These included increased proportions of CD69+ T resident memory cells of the T effector memory phenotype, as well as preferential coexpression of CD69 and CD103, on the gut-derived cells. In contrast, CD69+CD103+ T resident memory CD8+ T cells from FRT, but not those from gut, preferentially expressed PD1. We further determined that a recently described population of CXCR4+ T inflammatory mucosal cells differentially expressed multiple other chemokine receptors relative to their blood counterparts. Our findings suggest that T cells resident in different tolerogenic mucosal sites take on distinct properties.
LncRNA GAS5 enhances tumor stem cell-like medicated sensitivity of paclitaxel and inhibits epithelial-to-mesenchymal transition by targeting the miR-18a-5p/STK4 pathway in prostate cancer
Authors: Lu Ting-Ting , Tao Xia , Li Hua-Lei , Gai Ling , Huang Hua , Li Feng
Published: March 2022

The onset of prostate cancer (PCa) is often hidden, and recurrence and metastasis are more likely to occur due to chemotherapy resistance. Herein, we identified downregulated long noncoding RNA (lncRNA) growth arrest-specific 5 (GAS5) in PCa that was associated with metastasis and paclitaxel resistance. GAS5 acted as a tumor suppressor in suppressing the proliferation and metastasis of paclitaxel-resistant PCa cells. GAS5 overexpression in vivo inhibited the tumor growth of xenografts and elevated PCa sensitivity to paclitaxel. Combination of GAS5 and paclitaxel treatment showed great potential in PCa treatment. Moreover, mechanistic analysis revealed a novel regulatory network of GAS5/miR-18a-5p/serine/threonine kinase 4 (STK4) that inhibits epithelial-to-mesenchymal transition (EMT) and enhances tumor stem cell-like-mediated sensitivity to paclitaxel in PCa. These findings provide a novel direction for the development of a potential adjunct to cancer chemotherapy that aims to improve the sensitivity of chemotherapy drugs in PCa.