bluuebunny/crossref_metadata_2025 huggingface dataset:
The effects of melatonin on the activity of the c-fos gene in the structures of the hypothalamic paraventricular nucleus under prolonged lighting
Authors: Bulyk R. Y. , Abramov A. V. , Bulyk T. S. , Kryvchanska M. I. , Vlasova K. V.
Published: August 2018

The effect of constant illumination as a stress factor on the state of the "early response" c-fos gene in the lateral magnocellular subnuclei of the paraventricular nucleus (lmPVN) of the hypothalamus of rats at different time intervals (day and night) has been studied. To identify c-Fos in histological sections of the hypothalamus, a secondary (indirect) immunofluorescence method is used. Expression of the product of this gene, the c-Fos protein, in animals kept under normal conditions of alternation of illumination and darkness, shows a clear-cut circadian character. There was a significant decrease in the area of the immunopositive sites of structures at night by 19.4% compared to daytime measurements. The average values of the areas of such immunopositive subnuclei sites varied also in subgroups of rats under light stimulation conditions, in which samples of lmPVN were selected for study at 2 pm and 2 am, but the differences between groups did not reach the level of reliability. Under conditions of light stress, the c-Fos concentration index decreased by 29.4% during the day, and by 16.5% at night in relation to similar values in the intact group. In animals that were in the standard light mode, the c-Fos protein concentration index was significantly higher during the day than at night. In the intact group, the night value of the c-Fos concentration index averaged only 71.5% of the daily value. In rats subjected to constant illumination, the day and night values of the c-Fos concentration index did not differ reliably. To correct stress-induced changes in the activity of the "early response" c-fos gene in the rat hypothalamus, melatonin (0.5 mg/kg body weight of the animal) was used. Injections of melatonin to rats exposed to constant illumination normalized the circadian rhythm of the area of the material immunoreactive to c-Fos, compared to the group of animals that did not receive melatonin. When using melatonin against the background of constant illumination, a sharp increase of the protein concentration in the lmPVN subnuclei of hypothalamus in daytime and less pronounced at night intervals was detected. Injections of melatonin to animals were also reflected in the daily dynamics of the index of c-Fos protein content in the lmPVN subnuclei under conditions of constant illumination. In the daytime observation period, the index was almost twice the experimental data on stressed animals without the introduction of the hormone, bringing it closer to normal. Prospects for further research in this sphere will allow us to better understand the place and role of subnuclei of paraventricular nuclei of the hypothalamus in the mechanisms of the formation of circadian rhythms of the rat brain.
Modeling the invasiveness of Ulmus pumila in urban ecosystems in conditions of climate change
Authors: Lykholat Y. , Khromykh N. , Didur O. , Alexeyeva A. , Lykholat T. , Davydov V.
Published: August 2018

Climatic change can influence the boundaries of the natural and alien plant species distribution. Fluctuations in air temperature, relative humidity and other factors can become a stimulus to initiation and / or intensification of the invasive nature of some adventive plant species, especially in areas with a high degree of anthropogenic transformation. This paper presents an analysis of the current state and a forecast of the invasiveness of the alien species Ulmus pumila L. (Asiatic elm) in the Northern Steppe Dnieper under conditions of climatic change. Two local U. pumila populations consisting of young different age trees were found during a route survey in the territory of the large industrial city Dnipro (48°28′00″ N, 35°01′05″ E) in its left-bank and right-bank parts.The seed origin of both local populations of Asiatic elm is confirmed by the fact that the young plants were spaced at a distance of 50 to 120 m from adult trees, which could potentially be parent plants. Both the left-bank and right-bank populations of U. pumila were located on abandoned construction sites, where there were numerous reinforced concrete slabs, piles and abundant construction debris. In both U. pumila local populations, 100 different-aged trees were randomly selected throughout the site, and their age and the morphometric parameters were measured to simulate the development process of the detected populations, provided the current trends of climate change continue. Analytical dependence of the number of trees in the left-bank local U. pumila population on development time was described by a polynomial model with a determination coefficient of 98.3%. The graphic representation of this model had a sinusoidal character, and a similar dynamic of left-bank population growth in the subsequent years was suggested. The dynamic of the number of trees in the right-bank local Asiatic elm population was described by an exponential model with a determination coefficient of 84.4%, and its graphical representation was exponential. According to the forecast, by 2020, the number of plants in the right-bank local population of U. pumila can increase 4-fold in comparison with 2015 while maintaining the current dynamic of population development. Thus, the created mathematical models adequately described the dynamics of development of both local populations during the last 15 years and predicted their subsequent intensive growth, confirming the initiation and intensification of the invasive nature of the alien species U. pumila by climatic change in the Steppe Dnieper.
Cortex electrical activity during switching of motor programs among men and women
Authors: Korzhyk O. V. , Pavlovych O. S. , Dmytrotsa O. R. , Morenko A. H.
Published: August 2018

The inhibition of motor response is considered as an important aspect of executive control, as a way of changing behaviour. Gender, as a biological characteristic, stipulates different peculiarities of brain processes and, as a consequence, different behaviour of men and women. In the context of the Stop-Change task, the aim of our study was to examine whether there were differences in the brain processes between men and women. The method of “event-related desynchronization / synchronization” – ERD / ERS EEG – was used to clarify that issue. 36 men and 38 women, healthy, between the ages of 18 and 22, right-handed, participated in the experiment of compliance with bioethical requirements. The application of Stop-Change task required from the participants under the condition of a low tone (600 Hz sound) to quickly press with the help of the index finger and release the left button of the remote control. If there was a high tone (1600 Hz sound) the participant had to rapidly press and release with the help of middle finger the right button of the console. The prevalence of event-related synchronization phenomena of the α- and β-EEG-activity in cortical areas was distinguished in groups of men and women. It was apparently related to some deactivation of the cortex during the switching of motor program that was launched. At the same time, cortical electrical activity acquired certain specific features of the frequency-spatial organization, which could indicate the existence of certain gender characteristics of the brain processes. The weaker ERG EEG among women (compared with men) at 10 Hz, 16 Hz in symmetrical frontal and left central and parietal areas was found. Instead, the relative increase of ERS EEG among women was set in the range of 10 Hz (right central areas), 13 Hz (frontal central areas) and 19 Hz (central parietal areas). Gender differences in the electrical activity of the cortex in the range above 25 Hz of the EEG were characterized by some instability of the ERS and ERD responses in the frequency and spatial aspects.
Triticum spelta: Origin, biological characteristics and perspectives for use in breeding and agriculture
Authors: Babenko L. M. , Hospodarenko H. M. , Rozhkov R. V. , Pariy Y. F. , Pariy M. F. , Babenko A. V. , Kosakivska I. V.
Published: August 2018

In today’s wheat production, the trends focused on the revival, selection and implementation of forgotten regional grain crops, the so-called "antique" cereals, have been clearly identified. One of these is the ancient hexaploid species of wheat – spelt (Triticum spelta). One of the main reasons that have contributed to the revival of this type of wheat in recent years is its tolerance to growing conditions and capacity to endure the natural and climatic factors of the environment, which allows it to be grown without an excessive use of plant protection products. It is precisely because of this feature that hulled wheat is referred to as "environmentally friendly”. Spelt is capable of yielding stable crops without strict adherence to the production technology and may be a great alternative to soft wheat. The growth in demand for this crop is also due to a complex of economic and valuable traits inherited from its wild ancestors. This review analyzes and summarizes the information about the origin of spelt, presents biological characteristics, discusses the perspectives for using the species in breeding work when implementing interspecific hybridization and compares the structure and genome evolution. The achievements on the revival of spelt as an independent species and its use as a source of economic and valuable traits in breeding programs of crosses with soft wheat are highlighted, examples of successful use of the economic and valuable traits of spelt for the improvement and creation of new high-quality wheat varieties are presented. Data on this superiority of grain from this species over that of genetically close wheat species are presented. The varietals’ characteristics for spelt varieties of Ukrainian selection are given. Such important spelt characteristics as resistance to biotic and abiotic stressors, high quality grain composition and yield have been analyzed.
NOVEL OPTIMAL COORDINATED VOLTAGE CONTROL FOR DISTRIBUTION NETWORKS USING DIFFERENTIAL EVOLUTION TECHNIQUE
Authors: Anh Ho Pham Huy , Kien Cao Van
Published: August 2018

This paper investigates a Distributed Generators (DG) connected to distribution networks offer multiple benefits for power networks and environments in the case of renewable sources. Nevertheless, if there is not an appropriate planning and control strategy, several issues, such as voltage rise problems and increased power losses, may happen. In order to overcome such disadvantages, in this paper, a coordinated voltage control method for distribution networks with multiple distributed generators is proposed. This method is based on a differential evolution DE approach to obtain the optimal setting points for each control component. Furthermore this proposed method considers both of time-varying load demand and production, leading to not only an improvement in the voltage profile but also to optimally minimize the active power loss.
Let's Not Reinvent the Vocational Route: a comment on Labour's proposals for 16-plus
Authors: Allen Martin , Ainley Patrick
Published: August 2018

A National Education Service should be genuinely cradle to grave. This article focuses on the key area, often neglected, of 16-plus education and highlights the need for substantial public investment using the lessons of past experiences to build on the principle of 'a good general
education for all' at 16-19.
Imigrantes e Trabalho: representações discursivas acerca de uma relação de alteridade
Authors: Haubrich Gislene Feiten , Freitas Ernani Cesar de
Published: August 2018

O estudo visa analisar qual é a representação da relação de alteridade evidenciada por discursos institucionais sobre a atividade laboral para a inclusão de refugiados. Inicia-se com uma breve reflexão acerca da cultura brasileira (HOLANDA, 1995; DAMATTA, 1997) em confluência com a noção ergológica de atividade laboral (SCHWARTZ; DURRIVE, 2007) e culmina com a reflexão sobre dialogismo e alteridade (BAKHTIN, 2010; 2015). Estrutura-se a coleta de dados mediante pesquisa documental, cuja organização é sustentada pelo mapa de associação de ideias, que converge categorias oriundas da relação teoria e objeto empírico. Como corpus, elencam-se: cartilhas publicadas em 2015 pela Agência da ONU para Refugiados (ACNUR). O principal resultado evidencia que os discursos analisados expressam um vínculo com refugiados motivado pela monetização da identidade e parece refletir certo fechamento à alteridade.
Narrativas da dor: o Facebook como espaço de discussão de saúde e doença
Authors: Pessoni Arquimedes
Published: August 2018

O trabalho busca apresentar as interações realizadas entre membros do grupo do Facebook denominado “Eu tenho Síndrome da Cauda Equina” por meio do registro de narrativas da dor e busca por melhoria de qualidade de vida através de troca de informações sobre a doença. Trata-se de um estudo baseado na metodologia de netnografia que analisa as narrativas dos membros e identifica a forma como a memória das dores física e psicológica são compartilhadas entre si.
Predictive Value of Neutrophil to Lymphocyte Ratio in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease v1
Authors: Teng Fei , Ye Huan , Xue Tianjiao
Published: August 2018

Objective: This study aimed to determine the predictive value of the neutrophil to lymphocyte ratio (NLR) in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Methods: A retrospective study was conducted from March 2012 to May 2016 in Fuxing Hospital, Capital University of Medical Science. We collected 906 cases (525 males, 381 females, mean age 81.86±9.75 years) diagnosed with AECOPD. The NLR was calculated from their white blood cell (WBC), neutrophil (NEU), and lymphocyte (LYM)counts, which were obtained at laboratory examination. Result: After treatment, 698 patients with AECOPD improved. The NLR was higher at admission (6.89±6.82) than after treatment (4.19±5.11) (P=0.000). The area under the receiver operating characteristic curve (AUC) of the NLR for predicting the 28-day mortality rate was 0.737. Using 8.130 as the critical NLR value, the sensitivity was 60.5%, and the specificity was 74.8%. The AUC of the NLR for predicting the frequency of the need for invasive mechanical ventilation was 0.732. Using 10.345 as the critical NLR value, the sensitivity was 54.3%, and the specificity was 84.8%. The AUC of WBC, NEU and LYMfor predicting 28-day mortality and the need for invasive mechanical ventilation in these patients were all less than 0.7. An increased NLR was an independent risk factor for 28-day mortality (OR=1.067, P=0.000), intensive care unit occupancy (OR=1.046, P=0.000), and the need for invasive mechanical ventilation (OR=1.042, P=0.000). Compared with those patients without comorbidities, patients with renal dysfunction or upper gastrointestinal bleeding had an increased risk of death within 28 days (OR=3.102, OR=4.598, respectively), ICU admission (OR=2.228, OR=3.103, respectively), and the need for invasive mechanical ventilation (OR=3.572, OR=4.279, respectively). Conclusion: In patients with AECOPD, the accuracy of the NLR for predicting the 28-day mortality rate and frequency of the need for mechanical ventilation was significantly higher than the accuracy of WBC, NEU and LYMcounts. AECOPD patients with an NLR≥8.130 had higher 28-day mortality rate, while those with an NLR ≥10.345 were more likely to need invasive mechanical ventilation.
Adult mouse testis cell dissociation (on ice) v1
Authors: Mahoney Robert
Published: August 2018

This protocol is used to dissociate adult (8-10 week) mouse testis into a single cell suspension. The entire procedure is carried out 'on ice', reducing artifact gene expression changes. The yield is 5.4 million cells from 25 mg tissue and the viability is ~99%.
COMPARATIVE EVALUATION OF MICROBIOCENOSES OF THE CERVICAL CANAL DISCHARGE AND THE EJACULATE IN MARRIED COUPLES
Authors: Pochernikov D. G. , Postovoytenko N. T. , Strel’nikov A. I. , Pochernikova M. N.
Published: August 2018

The study objectiveis to perform comparative evaluation of the microbiocenoses of the cervical canal discharge and the ejaculate in married couples using standard bacteriological culture and real-time polymerase chain reaction (RT-PCR) test systems Androflor for men and Femoflor for women.

Materials and methods. Retrospective analysis of medical histories of 154 married couples seeking medical help in the preconception period was conducted. All patients were divided into 2 groups: in 121 married couples, standard bacteriological cultures of the cervical canal discharge and the ejaculate were evaluated; in 33 couples, analysis of the cervical canal discharge and the ejaculate was performed using RTPCR test systems Androflor and Femoflor.

Results. Monoinfection was significantly more frequent in the ejaculate than in the cervical canal discharge (p <0.05). In women, cultures were significantly more frequently identified as sterile compared to men (p = 0.01). According to the results of standard bacteriological study, in most observations microbiocenoses of the cervical canal discharge and the ejaculate of married couples didn’t match fully in microorganism composition (69.4 %) and matched exactly only in 18.2 % of cases. Evaluation using RT-PRC showed different microorganisms in the microbiocenoses of the ejaculate and the cervical canal discharge in 48 % of observations.

Conclusion. The study demonstrates the uniqueness of urogenital microbiocenoses and attests to the necessity of examination of both partners at the stage of preconception preparation and unacceptability of prescribing the same treatment to both partners.
LONG-TERM RESULTS OF TREATMENT OF PATIENTS WITH CHRONIC NONBACTERIAL PROSTATITIS AND INCREASED LEVEL OF SPERM DNA FRAGMENTATION WITH THE PROSTATILEN® AC DRUG
Authors: Borovets S. Yu. , Rybalov M. A. , Gorbachev A. G. , Al’-Shukri S. Kh. , Levina A. V.
Published: August 2018

The study objectiveis to evaluate the results of treatment of patients with chronic nonbacterial prostatitis, increased level of sperm DNA fragmentation, and concomitant reproductive function disorders with the Prostatilen® AC drug 1, 2, and 3 months after the end of therapy.

Materials and methods. Thirty five men aged 21–46 years (mean age 31.3 ± 4.3 years) with a verified diagnosis of “chronic nonbacterial prostatitis, associated reproductive function disorders, history of early-stage missed miscarriage in a wife/sex partner” were examined. All patients received Prostatilen® AC as rectal suppositories daily for 10 days with a repeat course 20 days later. Before and after the treatment, as well as after 1, 2, and 3 months after its end, the fraction of spermatozoa with fragmented DNA was measured in all patients using sperm chromatin structure assay with flow cytofluorometry. The risk of decreased fertility was considered low if the number of spermatozoa with fragmented DNA was 15 % or lower (this value is considered the norm). If DNA fragmentation was 16 % or higher, it was considered increased.

Results. The fraction of spermatozoa with fragmented DNA significantly decreased during the treatment, and 1 month after the end of the therapy it was 7.5 ± 4.2 % (prior to treatment it was 17.8 ± 6.7 %) (p <0.005). Prior to Prostatilen® AC treatment, enhanced DNA fragmentation was observed in 18 (51 %) patients, 1 month after treatment – only in 6 (17 %); the difference is statistically significant (p <0.001). Two months after the end of treatment, increased level of DNA fragmentation was detected in 7 (20 %) patients, 3 months after – in 15 (42 %) patients. Aside from that, if the fraction of spermatozoa with fragmented DNA was more than 30 % before treatment, then a decrease in this value during treatment wasn’t statistically significant.

Conclusion. Prostatilen® AC promotes a reduction in the level of sperm DNA fragmentation in patients with chronic nonbacterial prostatitis. A steady positive effect persists for 2 months with a tendency to weaken at the end of month 3 which indicates advisability of repeated courses of Prostatilen® AC treatment 2 months after the end of therapy.
Economic evaluation of postoperative hypofractionated radiation therapy in patients with breast cancer
Authors: Afonin G. V. , Ragulin Yu. A. , Avxentyeva M. V. , Gulidov I. A. , Ivanov S. A. , Kaprin A. D.
Published: August 2018

Breast cancer remains the most common malignant neoplasm in women. According to the current standards, radiation therapy is one of the most important components of the multi-disciplinary treatment. The efficacy of the postoperative radiotherapy in both the traditional fractionation regimen and in the hypofractionation mode is not questioned. Contrary to the conventional fractionation, hypofractionation implies an increase in the daily dose and a reduction in the total treatment time. This approach helps reduce the treatment costs in patients with breast cancer while maintaining a high treatment efficacy and quality of life.

The aim of the study was to analyze the economic efficiency of the dose hypofractionation as compared to the traditional mode of dose fractionation during postoperative radiation therapy in patients with breast cancer.

Materials and methods. The study included 220 patients with breast cancer who received a combined treatment. Of these, 120 patients (study group) received hypofractionated radiotherapy (40.5 Gy in 15 fractions) whereas 100 patients of the control group were treated by the conventional therapy of 50 Gy in 25 fractions. Patients of the both groups were comparable by stages of the disease, systemic treatment, age and molecular type of tumor. The cost of treatment was calculated from the price list of this research center.

Results. The present economic analysis showed that the method of hypofractionation was more (30% on average) cost-efficient than the conventional regimen while both modalities produced similar rates of total and relapse-free survival. We were then able to identify the main items in the list of medical services that contributed to the estimated difference in the treatment costs. Reducing the number of examinations and the treatment duration help reduce the expenditure of this medical organization.

Сonclusion. Hypofractionation of postoperative radiotherapy in patients with breast cancer allows one to reduce the treatment costs as compared to the conventional fractionation regimen. The funds saved by optimizing the costs of postoperative radiation can be directed to the development of additional means of cancer treatment.
Positive and Negative Ambivalence of Trust to the Teacher Between Students with Different Styles of Pedagogical Leadership
Authors: Dorofeev V. , Mochalova Y.A.
Published: August 2018

The model of two types of ambivalence of student’s confidence in the teacher is presented - positive and negative. Integration of psychological parameter ("psychological health" of the subject of the trust) determined by features of a ratio of trust/mistrust and a formalized (construct of the measurement of ambivalence) determined by method of measurement and statistical technology of the analysis of data is the basis for differentiation. In longitudinal analysis and taking into account the contradictoriness of the trust object as the determinant of ambivalence, an empirical verification of the validity of the model was carried out on the sample of students (N = 78) and teachers (N = 4). The statistically significant prevalence of students with a negative ambivalence of confidence in a controversial (liberal) style compared to a consecutive (authoritarian) one is established. A decrease (statistically reliable in the liberal style) of the proportion of such students as the time of interaction with teachers has been increased. The empirical results are interpreted substantively.
Competence Approach in the Scientific Paradigm of Russian Education
Authors: Ulyanina O.A.
Published: August 2018

The article analyzes the essence and content of the competence approach in education from the position of domestic researchers. The stages of formation and development of the indicated approach are described: the first stage of categorically–conceptual uncertainty; the second stage of the existence of multiple interpretations of key categorical units and the blurring of the boundaries of concepts competence / competence; the third stage of legal consolidation of the above–mentioned concepts at the state level. The necessity of changing the educational paradigm is substantiated, the existing problems in the preparation of specialists competitive on the labor market are noted. The circle of unresolved questions in the competence approach and the ambiguity of the interpretations of its key conceptual units are outlined. In this connection, the existing views of the scientific community are being studied both on the correlation of the concepts of competence / competence and on their content characteristics. Based on the examination of existing approaches, it is concluded that competence is a systemic concept, as an important new formation of the individual, which arises in the course of training and the subsequent development of professional activity, and competence as its component. Through the prism of the description of the categorical–conceptual apparatus of the competence approach, its conceptual positions in the theory and practice of modern education and training of personnel are examined.
Effect of CRP and lactate clearance in predicting outcome of emergency abdominal surgeries
Authors: Pandey Vinod Kumar , Singh Rahul , Nagarwal Neeraj , Singh Vaibhav , Singh Santosh Kumar
Published: August 2018

Background: Emergency abdominal condition had good prognosis if they diagnosed early and had better prognosis. Many biological parameters were considered to reduce postoperative complications. This study aims to study the effects of CRP and 24-hour lactate clearance on morbidity and mortality of patients undergoing emergency abdominal surgery.Methods: All the patients undergone surgery for emergency abdominal conditions over a period of 1 year were included. Patient age of below 15 years and above 70 years were excluded.Results: In the present study of 86 patients, patients whose preoperative CRP level <150 mg/dl and preoperatively CRP >150 mg/dl had mortality of 1 and 9 patients respectively (p = 0.049), wound discharge among 12 and 9 patients respectively (p = 0.113), wound dehiscence among 7 and 9 patients respectively (p = 0.909) and respiratory complications among 2 and 11 patients respectively (p = 0.049). In the present study of 86 patients, patients whose 24 hour lactate clearance of <10% and >10% had mortality of 4 and 3 patients respectively (p = 0.0003), wound discharge among 5 and 16 patients (p = 0.119), wound dehiscence among 5 and 11 patients (p = 0.023), respiratory complication among 5 and 8 patients (p = 0.002), prolonged ileus among 3 and 3 patients respectively (0.007).Conclusions: Preoperative CRP level >150 mg/l associated with higher chances of mortality, respiratory complication and postoperative ileus. 24-hour lactate clearance < 10 % associated with higher chances of mortality, wound dehiscence, respiratory complication and postoperative ileus.
Demography and etiology of congenital sensorineural hearing loss in children
Authors: Shrivastava O. P. , Gupta Anuj
Published: August 2018

Background: The prevalence of sensorineural hearing loss (SNHL) is 2-3 per 1000 live births in India, and out of 1000 babies, 1 is having profound degree of hearing loss at birth or in the pre-lingual age group. Hearing loss is categorized as syndromic or non-syndromic hearing loss. The present study was done to identify and diagnose children with SNHL and study the etiological profile, so that all necessary timely precautions may be taken as SNHL in pediatric age group affects not only development of speech and language, but also emotional, social and behavioural development.

Methods: A cross-sectional observational study was carried out in Department of ENT of a tertiary care centre, in 50 children with congenital SNHL. Data on epidemiological and etiological factors were collected. All cases were analyzed for detailed history and underwent clinical and audiological assessment.  

Results: Majority of cases presented between 2 and 4 years of age, however age of detection of congenital deafness by parents was most commonly observed in 6-12 months of age. Out of 50 cases, the maximum number of cases [14 (28%)] were having history of antenatal complications, 11 (22%) cases were having adverse perinatal and postnatal history, while in remaining cases, the etiological factors remained undetermined. In one case associated syndrome was observed (Van der Hoeve’s syndrome).

Conclusions: The increased occurrence of etiologies in this study was of prenatal origin, followed by perinatal origin. The present study conducted at a tertiary centre reflects the need of 'High risk' registry maintenance with active surveillance and subsequent screening for early detection of hearing loss.

 
An epidemiological study of allergic contact dermatitis in Greece: prevalence of sensitization to an adapted European baseline series’ allergens
Authors: Tagka Anna , Stratigos Alexandros , Stavropoulos Panagiotis , Rigopoulos Dimitrios , Chatziioannou Argiro
Published: August 2018

Background: Contact dermatitis is a common skin disorder related to environmental exposures affecting, all age groups, and both genders. The pattern of contact sensitization to a series of allergens included in the European baseline series has already been studied for a number of EU countries by the ESSCA Network. The current study aims to explore the patterns of contact dermatitis in Greece through a patch test against a large number of allergens provoking contact dermatitis.

Methods: Retrospective analyses of routine data of 668 patients were collected during 2014 in the Laboratory of Patch Testing, National Referral Centre of Occupational Dermatoses. Sensitization in all cases was tested with a battery of 28 allergens of the European baseline series and additional ones aiming to identify new sensitizations to inform the National baseline of allergens; information for an extended MOAHLFA index was also collected.

Results: One at least positive result was found in 61.5% of the patients while 19.1% of those found to be sensitized in two or more allergens. Nickel sulphate, fragrance mix and balsam of Peru were the most prevalent allergens in the total population, as well as with respect to gender. Nickel is the most frequent allergen of baseline series, a result which is in agreement with other reports.

Conclusions: Allergic contact dermatitis surveillance is of great importance towards the clinical and systematic understanding of the disease. Further studies should be directed towards that end, in order to facilitate more effective health policies.
Perfil Valorativo e Saúde Geral de Homens Usuários da Atenção Básica
Authors: Mariano Tailson Evangelista , Medeiros Emerson Diógenes de , Gouveia Valdiney Veloso , Sales Hemerson Fillipy Silva , Nascimento Anderson Mesquita do
Published: August 2018

O objetivo desta pesquisa foi conhecer o perfil valorativo, bem como a saúde mental geral de homens atendidos pelos serviços de atenção primária de uma cidade litorânea do Piauí. Para isso contou-se com uma amostra não probabilística de 153 participantes, em sua maioria solteiros (70,9%), com idades entre 20 e 58 anos (M = 27; DP = 9,1), que utilizam os serviços das Unidades Básicas de Saúde (UBS) desta cidade. Os participantes responderam ao Questionário de Valores Básicos (QVB-18) e o Questionário de Saúde Geral (QSG-12). Os resultados identificaram os valores sobrevivência (M = 6,33), maturidade (M = 6,33), religiosidade (M = 5,98); e a subfunção existência (M = 6,04) como os mais priorizados pelos usuários. Encontrou-se também uma relação negativa (p < 0,05) entre saúde geral e as subfunções valorativas existência (- 0,17) e normativa (- 0,27). Não foram encontrados casos de incidência de distúrbios mentais leves. Espera-se que estes achados possam ser usados na elaboração de estratégias que levem a uma maior aderência da população masculina ao cuidado com a própria saúde e para o desenvolvimento de campanhas específicas para esta população, considerando suas peculiaridades e o contexto social.
Vitimização e Percepção do Bullying: Relação com a Sintomatologia Depressiva de Adolescentes
Authors: Cavalcanti Jaqueline Gomes , Coutinho Maria da Penha De Lima , Pinto Adriele Vieira de Lima , Silva Karla Costa , Do Bú Emerson Araújo
Published: August 2018

A presente pesquisa objetivou conhecer a relação entre vitimização, percepção acerca do bullying, e sintomatologia depressiva no contexto de adolescentes escolares. Para isso, contou-se com uma amostra de 243 adolescentes com uma média de idade de 14,81 (DP=1,41). Esses responderam à Escala de Percepção sobre o Bullying Escolar, à Escala Califórnia de Vitimização do Bullying, e ao Inventário de Depressão Infantil (CDI-20). Os principais resultados apontaram para efeitos da vitimização na percepção do enfrentamento frente ao bullying e na sintomatologia depressiva. Também foram verificados que os alunos do sexo feminino, do ensino médio, que se sentem seguros na escola, apresentaram uma maior percepção de enfrentamento frente ao bullying. Já os alunos do sexo masculino, do ensino fundamental, que se sentem inseguros na escola, apresentam-se como sendo os mais vitimizados. Quanto à sintomatologia depressiva, os alunos do ensino fundamental e que se sentem inseguros na escola, apontaram para maiores índices. Ademais, confia-se que esses achados podem contribuir para um aprofundamento teórico e conceitual acerca do bullying e seu correlato com a depressão em escolares adolescentes. Espera-se que os resultados desse estudo possam contribuir para implementação de políticas públicas voltadas para promoção de saúde desse grupo identitário.
MENGIDENTIFIKASI KEMUKTABARAHAN TAREKAT SYAHADATAIN
Authors: Rosyid Moh
Published: August 2018

This article discusses about Shahadatayn tarîqah, one of lesser-known tarîqah in Indonesia. The writer explores it from a primary source written by Abah ‘Umar, the founder of this tarîqah and other supporting references. To be a member of Shahadatayn tarîqah, one is acknowledged through an inaugural ceremony (bay‘at), ḍuhâ and tahajjud praying in fourty days, reciting ṣalawât tunjînâ, wirid, Asmâ’ Nûr al-Îmân, and Asmâ’ al-Ḥusnâ. Shahadatayn is known for its uniqueness such as implementing the meaning of shahâdat in daily life, wearing white attire and turban when performing prayer, chanting after the obligatory prayers, ḍuhâ, tahajud, and other sunna prayers. Shahadatayn tarîqah is not as famous as the other tarîqah as it has not been listed in the JATMAN as mu‘tabar version. This is because there is no murshid transformation from the Prophet Muhammad and continues through the path of the ṣâlih to the murshid. JATMAN version can not be an absolute reference for it is within the circle of NU and not all tarekat residents are NU members. Furthermore, the actual Shahadatayn has a murshid lineage, i.e. from Prophet Muhammad, Sharif Hidayatullah, and Abah ‘Umar who is now passed on by his descendants. Although it is realized that the genealogy is not as many other tarîqahs, but the content of his teachings is in line with the guidance of the Prophet Muhammad.
El teatro histórico como ámbito educativo. Análisis de cuatro obras para conmemorar el triunfo de la República en Querétaro, México.
Authors: Latapí Escalante Paulina
Published: August 2018

Se parte del supuesto central de que las obras de teatro histórico, por las formas en que conjugan cogniciones y emociones, producen conocimiento a través de mecanismos de alto impacto. Se comprueba, tras la revisión de los estados del conocimiento más recientes en el campo de la enseñanza de la historia, que el estudio de ámbitos no formales de enseñanza y la emocionalidad, son temas que es necesario investigar. La presente investigación focalizó en cuatro obras de teatro histórico. Su estudio requirió de una metodología interdisciplinaria que trenzó conocimientos aportados por la filosofía, la antropología, la psicología y la neurociencia con los cuales se construyeron instrumentos de análisis que se procesaron mediante herramientas etnográicas aportadas por la Teoría Fundamentada. Los resultados arrojan categorías que explican la relación entre cogniciones y emociones suscitadas por las obras de teatro, dan cuenta de los insumos que las provocan, puntualizan cómo son un vehículo para generar empatía en relación a la adopción de perspectivas y a la humanización en relación con saberes previos. El trabajo es parte de la tesis doctoral de la Universidad Autónoma de Barcelona, bajo la dirección del doctor Joan Pagès Blanch, y de la investigación registrada en la Universidad Autónoma de Querétaro.
INVESTIGACIÓN E HISTORIAS RECIENTES ENSEÑADAS en la Nord Patagonia
Authors: Funes Graciela , Muñoz María Esther
Published: August 2018

Este texto busca conocer las potencialidades de la enseñanza de las historias recientes para la construcción de ciudadanías múltiples y democráticas, que exigen una educación para la responsabilidad y la participación accionada a partir de enseñanzas con fundamento ético político. La investigación, de carácter cualitativo, se desarrolla en instituciones públicas de enseñanza elemental y media de varias ciudades de las provincias de Río Negro y Neuquén, y busca contribuir al conocimiento de la formación docente en historia.

 

La enseñanza de la Historia Reciente es altamente compleja, por lo que su presencia se recontextualiza desde múltiples abordajes. Pensar en el presente históricamente conlleva un reto epistemológico y un replanteo acerca de modelos historiográficos. Sin embargo, ello no significa ausencia en las aulas. Si bien, dar cuenta de los procesos recientes en la enseñanza, les exige a los/as docentes revisar y repensar en torno a estos retos y desafíos, supondría que entienden su importancia desde el compromiso de posibilitar y favorecer a la formación de ciudadanías activas, críticas y responsables con los problemas de los presentes por venir. Cuestiones abordadas en el marco de contextos diversos y heterogéneos.
CRIANÇAS FAZENDO ARTE: processos de criação artística e formação profissional docente para a educação infantil
Authors: Cunha Sandra Mara da
Published: August 2018

Aprender arte por meio de processos criativos remete diretamente às crianças pequenas, exploradoras de lugares e investigadoras de gestos, movimentos, sons, cores e suas misturas. A aprendizagem da arte na Educação Infantil é objeto deste artigo, de natureza ensaística. Aqui, o objetivo é buscar conexões entre os processos criativos em arte com crianças pequenas, considerando o papel fundamental que as professoras desempenham na promoção desta aprendizagem. Fundamentado nos diálogos entre projetos educativos em arte desenvolvidos com crianças pequenas e os estudos da infância, traz elementos que apontam caminhos possíveis para a arte na Educação Infantil. Como resultado, as professoras, em formação e no exercício docente, são conclamadas a reconfigurar suas atuações ao trabalhar em parceria com as crianças, experimentando materiais e modos de lhes dar vida em uma abordagem pedagógica centrada nos processos de criação artística.
Transformation of Scientific Research Into Teaching-A Case of Enzymatic Mechanism and Kinetics
Authors: Cong Fangdi , Wang Xiaohong , Li Ping , Zhang Shulin
Published: August 2018

It is one of main tasks in university teaching to solve the contradiction between scientific research and teaching, so as to return the present teaching work to the essence of university education, effectively imparting the professional knowledge and technical ability to undergraduates. An effective strategy for solving this problem is to carry out teaching work by the transformation of scientific research into teaching. That is to say, the scientific research results obtained by teachers are integrated into course teaching, or students are guided into the scientific research activities undertaken by teachers in some way. Here taking the teaching content of enzymatic mechanism and kinetics in biochemistry, one teaching knowledge point with great difficulty, as an example, the paper expounds the teaching idea, selecting content, designing plan and completing effect by the method of scientific research into teaching. It is minded to be taken as a useful case referred by university teacher at work to implement the transformation of scientific research into teaching, so as to improve the teaching effect of courses, especially those important, in universities.
Characterization of Sardinian Bentonite
Authors: Mannu Alberto , Vlahopoulou Gina , Petretto Giacomo Luigi , Sireus Veronica , Mulas Gabriele
Published: August 2018

The employment of clays in industry and on laboratory scale is still of interest, despite their long history. The chemical-physical characteristics of such material are strongly related to their geographical origin and the availability of proper characterization techniques is of great importance in order to gain as more information about their behavior when utilized as filling materials. In the present contribute a physical characterization by meaning of Thermogravimetry and N2 physisorption, including a thermal stability evaluation, of samples of Sardinian bentonite collected from the Alghero area (Italy) is reported.
Boundary Bound Diffraction: A Combined Spectral and Bohmian Analysis
Authors: Tounli Jalal , Alvarado Aitor , Sanz Ángel S.
Published: August 2018

The diffraction-like process displayed by a spatially localized matter wave is here analyzed in a case where the free evolution is frustrated by the presence of hard-wall-type boundaries (beyond the initial localization region). The phenomenon is investigated in the context of a nonrelativistic, spinless particle with mass m confined in a one-dimensional box, combining the spectral decomposition of the initially localized wave function (treated as a coherent superposition of energy eigenfunctions) with a dynamical analysis based on the hydrodynamic or Bohmian formulation of quantum mechanics. Actually, such a decomposition has been used to devise a simple and efficient analytical algorithm that simplifies the computation of velocity fields (flows) and trajectories. As it is shown, the development of space-time patters inside the cavity depends on three key elements: the shape of the initial wave function, the mass of the particle considered, and the relative extension of the initial state with respect to the total length spanned by the cavity. From the spectral decomposition it is possible to identify how each one of these elements contribute to the localized matter wave and its evolution; the Bohmian analysis, on the other hand, reveals aspects connected to the diffraction dynamics and the subsequent appearance of interference traits, particularly recurrences and full revivals of the initial state, which constitute the source of the characteristic symmetries displayed by these patterns. It is also found that, because of the presence of confining boundaries, even in cases of increasingly large box lengths, no Fraunhofer-like diffraction features can be observed, as happens when the same wave evolves in free space. Although the analysis here is applied to matter waves, its methodology and conclusions are also applicable to confined modes of electromagnetic radiation (e.g., light propagating through optical fibers).
Competence Training  and  Incentives Medical ServicesSupport the Achievement of Nurses’ Performances in General Hospital of  Prof. W. Z. Johannes Kupang
Authors: Salesman Frans , Bayo Thresia
Published: August 2018

Background.Nurse gives professional nursing service to patients according to competence owned. Based on these services in the end of every year, nurses are given incentives for medical services as financial incentive. Purpose. To analyze the impact of competence training and incentives medical services’ distribution upon the achievement of nurse’s performances in General Hospital of W. Z. Johannes Kupang. Matterial and method. Observational survey research with cross sectional design. Population. Nurses in General Hospital of W. Z. Johannes Kupang. Technique. Total sampling technique with number of samples 183 respondents. Inclusive criteria of samples are willing to be interviewed, nurse’s status, permanent offices without limitation from particular working unit or poly in hospital. Independent variable: (1) competence training; (2) Incentives for medical services. Dependent variable; Nurse’s performance achievement. Variables are measured by using Lickert scale. Information are recorded through questionnaire. Analyzes using linier regression. Result. There are impacts of competence training (α=.000;ß=.489)and distribution of incentives for medical services(α=.012; ß=.152)upon nurse’s performances achievement in General Hospital of Prof.W. Z. Johannes Kupang. Conclusion.The training of nursing service status that could increase competences among nurses with affair incentives for medical services’ distribution simultaneously end up in the increasing of nurse’s performances achievement in a hospital
Experimental Validation of an Onboard Transient Luminous Events Observation System for VisionCube via Ground Simulation Environment
Authors: Kim Seho , Nam Taehyung , Jung Dongwon
Published: August 2018

The VisionCube is a 2-unit CubeSat developed in-house, of which the primary mission is aimed at detecting the occurrence of transient luminous events in the upper atmosphere and obtaining corresponding images from the low Earth orbit. An on-board TLE observation system of the VisionCube cubesat is designed and developed by incorporating a photon-sensitive MaPMT and a CMOS image sensor. Also, a distinctive TLE observation software which enables detecting the TLEs and capturing images in a timely manner is devised. By taking into account the limited resources of a small CubeSat in size and power, the on-board observation system is developed employing a system-on-chip design architecture by which both hardware and software can be integrated seamlessly. The purpose of this study is to investigate the functionality of the hardware and the validity of the software algorithm to show the on-board system will operate properly with no human intervention during the space operation. To this end, a ground simulation facility is constructed to emulate the space environment of the TLE occurrence using a set of UV LEDs inside a darkbox. Based on the analysis of the spectral and temporal properties of the TLEs, the randomly generated UV LED pulses are opted for verification scenarios for the TLE observation system. The validation results show that the hardware and the software algorithm of the on-board observation system can effectively detect the TLEs and obtain the images during the on-orbit operation.