bluuebunny/crossref_metadata_2025 huggingface dataset:
Proteome profile of Nucleus Accumbens (NAc) uncovers the differential and sex-specific role of CRMP2 in CVMS induced mouse model of depression
Authors: Karisetty Bhanu Chandra , Duscharla Divya , Vijay Vincy , Patel Shashikant , Soren Kalyani , Kumar Arvind , Ummanni Ramesh , Chakravarty Sumana
Published: March 2024

Chronic stress plays a very important role in building pathogenesis of psychiatric disorders including major depressive disorder (MDD). Despite of the fact that the human females are more prone to stress vulnerability, molecular mechanisms of depression-like pathophysiology in female rodent models is less studied as compared to that in males. Previous reports showed that 6-days of chronic unpredictable stress (CUS) paradigm can induce depression-like mood disorders in female mice whereas 21-days of chronic variable multiple stress (CVMS) paradigm induces the similar phenotypes in both the sexes. The gene array studies on critically affected areas like nucleus accumbens (NAc) and hypothalamus have indicated that the molecular mechanisms underlying the stress susceptibility might be differentially regulated across the sexes. However, there is scarcity of studies on proteome changes associated with MDD. In this study we specifically attempted to identify altered protein expression in NAc of OVX, as well as both male and female mice on CVMS using 2-DE followed by MALDI-LC-MS/MS. From 2D gel analysis total of 46 significantly altered protein spots were selected (20 proteins in OVX female, 7 in the male and 19 in the intact female) and identified by MALDI-LC-MS/MS. Proteomics data followed by validation revealed dysregulation of neuropeptide, Collapsin response mediator protein-2, CRMP2 (also known as DPYSL2), crucial for neuronal growth and is known to be associated with neurodegenerative/psychiatric disorders. These findings suggest the importance of comprehending the function of these proteins in a significantly affected brain area under long-term stress conditions to address the occurrence and symptoms of depression in both men and women.
Mumps resurgence in India in the decade 2014-2023: A Trend and Geospatial Analysis
Authors: MD. Bashar , Gnanasekaran Sridevi
Published: March 2024

Background
Mumps, caused by the paramyxovirus, primarily affects children and adolescents and presents with parotiditis. Complications such as orchitis and meningitis can occur, especially in young adult males and vaccination reduces complications. Global mumps cases surged in the past decade, including regions like North and South America, Australia, and Iran. In India, a recent surge in mumps cases was reported in 2023. The current analysis was performed to assess the burden and trend of mumps in India over the last decade and geographical variations in its burden across India.
Methods
Using the weekly outbreak reports of Integrated Disease Surveillance Programme(IDSP) for the period of 2014 to 2023, number of mumps cases and outbreaks in India were plotted to see the trend of mumps in past 10 years. State wise spatial distribution of the number of mumps cases and outbreaks were also performed using QGIS for 2023 to ascertain geographical variation in mumps burden across India.
Results
Distinct peaks and troughs in mumps cases were observed, with notable increases in 2015, 2016, and 2019. Absence of reported cases in 2021 and a resurgence in 2023 were noted. Spatial analysis identified hot spots and clusters, indicating hyperendemic areas. State-wise wide variations were evident, with some states reported disproportionately higher number of outbreaks like Jammu and Kashmir. The impact of COVID-19 on mumps incidence was seen, with a decrease in 2020 and an increase in 2023.
Conclusion
Total number of mumps outbreaks and cases were reported to be highest in 2023 which is alarming and emphasizes the need for inclusion of mumps containing vaccine in form of MMR vaccine in the Universal immunization Programme (UIP) of India along with strengthening the mumps surveillance. These findings also underscore the importance of state-specific analyses and evidence-based interventions to address mumps outbreaks effectively in India.
Stoichiometric characteristics and weight analysis of soil carbon, nitrogen and phosphorus in urban park green space
Authors: Yang Fan , Zhang Jin , Feng Yumeng , Li Wenfang , Yang Xiuyun , Wu Xiaogang
Published: March 2024

In this paper, 136 surface soil samples (0 ~ 10cm, 10 ~ 20cm) were collected from 37 urban parks in the main urban area of Taiyuan City. Mathematical models were used to systematically analyze the effects of urban expansion, park years and different plant allocation patterns on soil carbon, nitrogen and phosphorus content. The purpose of this study is to provide guiding opinions on the sustainable and healthy development of land use management and landscaping in small and medium-sized cities represented by Taiyuan City. The results of the study show that: Soil SOC content in 0-10cm and 10-20cm soil layers decreased by 55.08% and 61.38% with the gradient of urban expansion, and soil TN content increased significantly by 54.38% and 54.48% with the increase of the years of park construction, respectively. The maximum soil TN content appeared in shrub woodland and shrub woodland, respectively. Were 2.02 ± 0.25 g·kg− 1 and 1.76 ± 0.27 g·kg− 1, respectively. C: N decreased significantly with the increase of urban gradient (P < 0.01), C: P decreased first and then increased with the increase of urban gradient (P < 0.01), and there was a significant difference between C: P and plant allocation mode (P < 0.05). SOC, TN and TP contents were significantly correlated with their stoichiometric ratios. Soil SOC and TN contents were the main factors affecting soil in this study area.
Enhanced compatibility and toughness of PHBV/PCL blends by ring-opening polymerization and hydrogen bonding of epoxy- terminated hyperbranched polyester
Authors: Huang jiawei , Jin Yujuan , Tian Huafeng , Kumar Rakesh , Fang Yiqi , Zhou Sudan , Tie Rui , Zhou Shuyi
Published: March 2024

Melt extrusion process was followed in order to improve the high crystallinity and poor toughness of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) blend materials. It was achieved by the incorporation of epoxy-terminated hyperbranched polyester (EHBP) elastomer into PHBV and polycaprolactone (PCL). EHBP cross-links PHBV and PCL through ring-opening polymerization of epoxy-terminated and carboxyl groups. Therefore, when the EHBP content was 3phr, the Young's modulus and tensile strength of the blends are increased to 750MPa and 15MPa, respectively, which was comparable to the biodegradable polymers used for packaging. Simultaneously, compatibility between PHBV and PCL has been improved and the particle size reduction of blends can be obviously observed in scanning electron microscope (SEM) images. Dynamic mechanical analysis (DMA) analysis revealed that PHBV and PCL showed improved compatibility with each other by the addition of EHBP. Differential scanning calorimetry (DSC) revealed that the decrease of crystallinity of the blend was consistent with the increase in mechanical properties. Additionally, all the bio-blends show good thermal stability. Food overall migration studies showed that the amount of migration of composite materials in contact with food was also far lower than the national standard value. Therefore, PHBV/PCL/EHBP blends are expected to be used in the field of food packaging.
Factor affecting Time-to-Recovery from Major Depressive Disorder (MDD): Case Study at Jimma University Specialized Hospital, Ethiopia
Authors: Barsisa Temesgen Soboka
Published: March 2024

Background
Major Depressive Disorder (MDD) is depression that leads to disability and know days it is ranked as the 3rd burden of disease through the whole world and predicted to be 1st at 2030. Despite majority of MDD patients delay recovery during treatment, factor affecting time to recovery is unstudied. Hence, the main objective of this study was to explore the factors that affect time to recovery of MDD patients.
Methods
The data was taken from Jimma University Specialized Hospital (JUSH), South West Ethiopia. The retrospective study design was used. The time until the recovery of 204 patients chart were checked for 3 year follow up period from January 2018 to January 2021. The AFT models were employed after checking the restrictive assumption of Cox-PH model.
Result
Then, the study resulted, 134 (66%) were recovered and 70(34%) censored out of 204 patients. The median recovery time of the patients was 31 months but it varies depending on the covariates included in the study. Weibull AFT model was selected as the best model based on AIC. Accordingly, MDD patients of age: \(\ge 57 (\widehat{{\upvarphi }}=1.61[95\text{\%}: 1.12, 2.32\left]\right)\), marital status: widowed \((\widehat{{\upvarphi }}=1.61[95\text{\%}: 1.28, 2.04\left]\right)\), and substance use: yes \((\widehat{{\upvarphi }}=1.31[95\text{\%}: 1.12, 1.52\left]\right)\) had significantly prolonged time to recovery relative to their reference group 18–30 age, single marital status and no substance use respectively and MDD patients of sex: male \((\widehat{{\upvarphi }}=0.75[95\text{\%}: 0.66, 0.84\left]\right)\), education level: high school \((\widehat{{\upvarphi }}=0.69[95\text{\%}: 0.53, 0.88\left]\right)\) and college & above \((\widehat{{\upvarphi }}=0.55[95\text{\%}: 0.42, 0.71\left]\right)\) and living style: not alone \((\widehat{{\upvarphi }}=0.77[95\text{\%}: 0.67, 0.89\left]\right)\) had significantly shorten time to recovery relative to their reference group sex: female, education level: illiterate and living style: alone respectively.
Conclusion
In conclusion, the finding of this study showed that age, sex, marital status, education level, living style and status of substance use were major factors affecting recovery time of MDD patients. It is recommended to make interventions based on these factors.
Psychosocial Factors Influencing Vaccine Hesitancy: A Study in the Context of COVID-19
Authors: Rahel
Published: March 2024

The COVID-19 pandemic has underscored the critical need to comprehend vaccine hesitancy, a multifaceted issue with substantial repercussions for the success of vaccination campaigns. This study delves into vaccine hesitancy within a cohort of 560 individuals. Within this group, 157 individuals (28%) opted to receive the Pfizer vaccine, while the remaining 403 (72%) expressed hesitancy towards vaccination. Hesitant individuals were further classified into five distinct categories: 210 harbored concerns about potential vaccine side effects, 172 were influenced by misinformation and disinformation, and 21 exhibited a historical mistrust of vaccines. Notably, our survey did not unearth any instances of vaccine hesitancy stemming from political polarization or access barriers. Furthermore, we conducted a comprehensive analysis of biological markers in the 157 vaccinated individuals to evaluate vaccine side effects. This analysis unveiled significant variations in blood test parameters, such as D-Dimer, CRP, and WBC levels, between the first week and three weeks following vaccination (p < 0.0001 and p = 0.001, respectively). To sum it up, our results indicate that the vaccination process is a standard and medically valid procedure. Nevertheless, several factors play a role in individuals' vaccine hesitancy. It is imperative for both the government and healthcare systems to provide accurate information to the public about the significance of vaccination. Recognizing and tackling these factors are essential for successful vaccination initiatives and, in the end, attaining widespread immunity.
Occupational Hazards/ Risks Among Dental Staff in Afghanistan
Authors: Azimi Shamila , Azimi Susan , Azami Mashal
Published: March 2024

Background: The risks that are exclusive to the dental care setting are known as occupational hazards in dentistry.
Aims: Dangers. This research analyses the prevalence of occupational hazards among dental staff in Afghanistan.
Methodology: A cross-sectional study, using an online survey including qualitative and quantitative questions. Data collection was started from 16th .03.2021 till 12th.05.2021 and completed by 206 dentists. The questionnaire was designed in Google form and data was collected by online link via social media such as “Facebook, and WhatsApp”.
Result: According to a survey the most common occupational hazards among dentists are musculoskeletal problems in Afghanistan. Among musculoskeletal problems, most of the responders had complained of backache while nobody had noticed any pain in their elbow joint. 55% of dentists were vaccinated for common diseases (HBV, HCV, HAV, etc.) and 41.6% were not vaccinated. 74% of participants strongly agreed that dentistry is a stressful field and 26.7% had a high level of fatigue due to work at the end of the day.
Conclusion: musculoskeletal problems especially backache are the most prevalent hazards among Afghan dentists and Continuing education programs have to be conducted to overcome these hazards.
التناص الأدبي في مسرحية "محمد صلى الله عليه وسلم" لتوفيق الحكيم
Authors: Nisa' Kholifah Wahidatun
Published: March 2024

One of the Egyptian famous writer is Taufiq Al-Hakim. Of the many drama scripts that he wrote, namely "Muhammad SAW" which is a biography of the life of the Prophet SAW which is outlined in the form of a drama. Of course a writer has the inspiration to be the main idea during the writing of his literary work. This is what is commonly referred to as intertextual. The problems examined in this research are: First, what are the forms of intertext in the drama script "Muhammad SAW" by Taufiq Al-Hakim? Second, what are the influences that arise on the drama script "Muhammad SAW?. The method used in this research is a qualitative descriptive method with a literature study approach. From the research results, it is founded that in the drama script "Muhammad SAW" there are 22 direct intertext and 9 indirect intertext. As for the influence of the previous texts on the drama script "Muhammad”, namely the value of the Islamic religion and the Al-quran as the foundation of drama script writing.
السجع في القرآن الكريم سورة عبس و التكوير و الانفطار (دراسة بلاغية)
Authors: Fitriah Maulidah , Abdul Hakim Muhammad Kamal Bin , Tajuddin Shafruddin
Published: March 2024

البحث العلمي، قسم تربية اللغة العربية كلية اللغات والفنون جامعة جاكرتا الحكومية، يناير 2022 م. يهدف البحث إلى الحصول على وصف البيانات عن السجع في القرآن الكريم سورة عبس والتكوير والانفطار لمساعدة الطلبة على فهم دراسة البلاغة بوضوح لأن العلماء راجعوا علومهم إلى القرآن. المنهج المستخدم في هذا البحث هو المنهج الوصفي التحليلي في سورة القرآن في عبس والتكوير والانفطار. يركز هذا البحث على القصائد الموجودة في سورة القرآن الكريم عبس والتكوير والانفطار. يعتمد مصدر بيانات البحث على دراسة مكتبية من آيات من القرآن الكريم، وكتب في تفسير القرآن، وكتب بلاغية، وصحف، وغيرها من الكتب المتعلقة بهذا البحث. واستنادا إلى تحليل البحث خلص إلى أن آيات القرآن في سورة عبس والتكوير والانفطار، هناك السجع المطرف والمتوزي والمرصع. والآية القرآنية في سورة عبس والتكوير والانفطار التي توجد السجع المطرف والمتوزي والمرصع التي تتكون من ٣2 شاهدا السجع : السجع المطرف (عبس : 3 شواهد، التكوير : ٨ شواهد، الانفطار : ٤ شواهد)، السجع المتوزي (عبس : ٨ شواهد، التكوير : ٥ شواهد، الانفطار : شاهد واحد)، السجع المرصع (التكوير : شاهد واحد، الانفطار : شاهدان).

الكلمة الرئيسية: السجع، القرآن، عبس، التكوير، الانفطار
إدارة جودة التعليم اللغة العربية في المدرسة
Authors: Mokoginta Siti Mustika Vevi , Hadawiyah Rabiatul , Syamsudin Ahmad , Hilmi Danial
Published: March 2024

تهدف هذه الدراسة إلى تحديد كيفية إدارة جودة تعليم اللغة العربية في المدارسة في إندونيسيا. تستخدم هذه الدراسة المنهج الوصفي النوعي باستخدام طرق دراسة الحالة البحثية. تم جمع البيانات عن طريق المقابلة والتوثيق. تشير نتائج هذه الدراسة إلى أن إدارة الجودة في تعليم اللغة العربية في المدرسة وجدت أ) أن تعليم اللغة العربية في المدارس يصبح أكثر ملاءمة ، من خلال بناء تعليم تفاعلي وملهم وممتع ومحفز. ب) يتحسن تعليم اللغة العربية في المدارس ، بحيث تصبح قادرة على تلبية معايير تخرج الطلاب ، من خلال بناء مرافق دعم التعليم مثل معامل اللغة وبيئات اللغة. تكشف هذه الدراسة أيضًا أن هناك عوامل تدعم نجاح تعليم اللغة العربية ، وهي العوامل الداخلية والخارجية ، مثل بيئة اللغة ، والتحفيز الذاتي ، والمعلمين المحترفين ، ومرافق التعليم المناسبة.
The Effectiveness of Using the SQ3R Method in Improving Maharah Qira'ah in Balaghah Learning at Al-Muhibbin Islamic Boarding School Tambakberas Jombang
Authors: Ulin Nuha Muhammad Afthon
Published: March 2024

This research comes from the results of observations of researchers at the Al-Muhibbin Islamic Boarding School Tambakberas Jombang, where in Balaghah learning, the ability to read material is meager, so it affects the level of understanding of students on Balaghah reading material besides the value of students in Balaghah learning is also common. So departing from this, the researchers used the SQ3R method, which was applied to the Al-Muhibbin students in learning Balaghah. This study aims to 1) determine the level of understanding of maharah qira'ah before and after the application of the SQ3R method in learning Balaghah at the Al-Muhibbin Islamic Boarding School Tambakberas Jombang; 2) to determine the effectiveness of using the SQ3R method in increasing maharah qira'ah in Balaghah learning at Al-Muhibbin Islamic Boarding School Tambakberas Jombang. The type of this research is quantitative research with the One-Group Pretest-Postest Design Research. The population of this study was all students of Al-Muhibbin Tambakberas Jombang, with a total of 1300 students. The sample in this study was 40 students. The research instrument used a test of understanding maharah qiraah, documentation, and observation sheets and then analyzed by descriptive and inferential analysis. The results of this study are 1) after the SQ3R method treatment showed that the understanding of the maharah qira'ah of students in Balaghah learning at the Al-Muhibbin Islamic Boarding School Tambakberas Jombang increased, they could conclude that the contents of the reading and understand the Balaghah material contained in the reading; 2) the effectiveness of the SQ3R method in learning Balaghah understanding of the maharah qira'ah of students in Balaghah learning at the Al-Muhibbin Islamic Boarding School Tambakberas Jombang can be concluded to experience a significant increase, as evidenced by the pre-test scores of students, namely 65 and post-test students of 78. So, it can be concluded that the use of the SQ3R method has high effectiveness in understanding the maharah qira'ah of students in Balaghah learning at the Al-Muhibbin Islamic Boarding School Tambakberas Jombang.
Arabic Learning Curriculum Based on Santri Adaptation in the Era of Society 5.0: Concepts and Implications
Authors: Ngarifah Imroatul , Bahtiyar Fadhli Hakim , Mufliha Mufliha , Ainiy Nurul , Mufidah Nuril , R. Taufiqurrochman R. Taufiqurrochman
Published: March 2024

Society 5.0 gives a new nuance to learning Arabic. Optimizing the use of cyber as a learning medium adds to the attractiveness of santri in learning Arabic. The purpose of this study is to determine the concepts and implications of the Arabic language learning curriculum based on the adaptation of students in the era of society 5.0. This research is library research that collects secondary data from various kinds of literature such as books, journal articles, and information from relevant official websites. The data that has been collected will be clasificated, followed by an in-depth discussion. The result of this research is that the Arabic language learning curriculum based on the adoption of santri in the era of society 5.0 combines the pesantren curriculum and other appropriate modern curriculum. It utilizes the latest technology as a media for Arabic learning.
Kitab “Al – ‘Arabiyah Lil Hayah” Limaharatul Kitabah ‘Ala Nadzariyati Abdurrahman bin Ibrahim Al - Fauzan
Authors: Amal Ikhlasul
Published: March 2024

Abstract : Writing skills in arabic teaching materials books are an important aspect that must be present. Arabiyah lil hayah TextBook became the handbook of first-year for student State Islamic University Maulana Malik Ibrahim Malang in the process of learning Arabic. All first-year students learn arabic writing skills using the book. This research was conducted to analyze the contents of Arabiyah lil Hayah (ALH) Textbook based on  Describing the content of material writing skills of ALH Textbook and Describing the evaluation of writing skills in ALH Textbook according to the perspective of Abdurrahman bin Ibrahim Al-Fauzan's . This research uses a qualitative approach in the form of Library Research. The data collection in this study uses the research of documentation of the contents of the book and sorting the material and evaluation of writing skills in it to be analyzed based on al-Fauzan analysis instruments. To present data and analysis researchers using content analysis techniques. The results of the study explained that the writing skills in the  Arabiyah lil Hayah Textbook is contained in each chapter with varying amounts, creative, and innovative.  The form of evaluation of writing skills in the Arabiyah lil Hayah Textbook Volume 2 is in accordance to the Perspective of Abdurrahman bin Ibrahim al-Fauzan. The form of evaluation presented can help students to improve their writing skills fundamentally, creatively and innovatively.
Analisis Minat Belajar Siswa Sekolah Menengah Pertama Terhadap Pelajaran Bahasa Arab
Authors: Ngarifah Imroatul
Published: March 2024

Tujuan penelitian ini ialah untuk mengukur minat belajar siswa terhadap bahasa Arab yaitu rasa suka siswa terhadap pelajaran bahasa Arab, ketertarikan siswa terhadap pelajaran bahasa Arab, keterlibatan siswa dalam pembelajaran bahasa Arab, dan perhatian siswa dalam pembelajaran bahasa Arab. Penelitian ini merupakan penelitian kualitatif deskriptif. Data primer diperoleh dengan menyebarkan angket kepada siswa. Pengambilan sampel menggunakan teknik ramdom sampling yang melibatkan 60 siswa. Hasil dari penelitian ini menunjukkan bahwa persentase dari rasa suka siswa terhadap pembelajaran bahasa Arab ialah 68%. Keterlibatan siswa dalam pembelajaran bahasa Arab mencapai persentase 75%. Ketertarikan siswa terhadap pembelajaran bahasa Arab memperoleh persentase 64%. Perhatian siswa dalam pembelajaran bahasa Arab mencapai persentase 72%. Adapun rata-rata minat belajar siswa dalam pembelajaran bahasa Arab memperoleh persentase 70% dengan kategori “sedang”. Berdasarkan hasil tersebut, maka untuk mencapai hasil belajar yang lebih efektif,  guru hendaknya berupaya untuk menjaga dan meningkatkan minat belajar siswa.
PEMBELAJARAN BERDIFERENSIASI PADA MATA PELAJARAN BAHASA ARAB
Authors: Murtadho Mohamad Aris
Published: March 2024

ملخص

التعلم المتمايز عبارة عن سلسلة من القرارات المنطقية التي يتخذها المعلمون والتي تستهدف احتياجات الطلاب. يستخدم التعلم التفاضلي مجموعة متنوعة من الأساليب (مناهج متعددة) في المحتوى والعمليات والمنتجات. يعد الالتزام بتنفيذ التعلم المتمايز وعدًا يربط نتائج تعلم الطلاب ويطور الاحتراف والعملية التعاونية التي تضمن التعلم الناجح للجميع. الالتزام بتنفيذ التعلم المتمايز بما في ذلك: (1) استخدام التقييم. ويشمل ذلك الانتباه إلى مدخلات الطلاب، والاستعداد، والاهتمامات ، والمواهب؛ (2) استخدام نتائج التقييم للتمييز بين بيئة التعلم والتعلم والتقييم؛ (3) اختيار استراتيجيات التعلم التي تناسب احتياجات الطلاب؛ (4) قم بإجراء تعديلات (يمكن إجراؤها في أي وقت) لتوقع الأشياء التي لا يمكن التنبؤ بها.

الكلمة الرئيسية: تعلم ، تمييز ، لغة عربية

Abstract

Differentiated learning is a series of common sense decisions made by teachers oriented to student needs. Differentiation learning uses a variety of approaches (multiple approaches) in content, processes and products. Commitment to implementing differentiated learning is a promise that binds student learning outcomes, develops professionalism and a collaborative process that ensures successful learning for all. Commitment to implementing differentiated learning, including: (1) Using assessment. This includes paying attention to student input, readiness, interests and talents; (2) Using the results of the assessment to differentiate the learning environment, learning, and evaluation; (3) Choose learning strategies that suit the needs of students; (4) Make adjustments (can be done at any time) to anticipate things that cannot be predicted.

Keywords: Learn, distinguish, Arabic language

 

Abstrak

Pembelajaran berdiferensiasi adalah serangkaian keputusan masuk akal (common sense) yang dibuat oleh guru yang berorientasi kepada kebutuhan siswa. Pembelajaran diferensiasi menggunakan berbagai pendekatan (multiple approach) dalam konten, proses dan produk. Komitmen dalam melaksanakan pembelajaran berdiferensiasi merupakan sebuah janji yang saling mengikat hasil belajar siswa, mengembangkan profesional dan proses kolaborasi yang menjamin keberhasilan belajar bagi semua. Komitmen pelaksanaan pembelajaran berdiferensiasi, meliputi: (1) Menggunakan asesmen. Termasuk di dalamnya memperhatikan masukan, kesiapan, minat dan bakat siswa; (2) Menggunakan hasil asesmen untuk mendiferensiasikan lingkungan belajar, pembelajaran, dan evaluasi; (3) Memilih strategi pembelajaran yang sesuai dengan kebutuhan siswa; (4) Membuat penyesuaian (bisa dilakukan kapan saja) untuk mengantisipasi hal-hal yang tidak dapat diperkirakan

Kata Kunci: Pembelajaran, Diferensiasi, Bahasa Arab
Forecasting Number of Inbound Tourists in India Adopting ARIMA Model
Authors: Manik Arora
Published: March 2024

This study focuses on estimating the occurrence of inbound tourists in India using univariate time series econometrics, the ARIMA model in particular. The tourism industry plays a significant role in India's economy, making accurate forecasts essential for effective planning and decision-making. The ARIMA model is known for its ability to analyze time series data, making it an appropriate tool for predicting future tourist arrivals. Data from previous years of inbound tourist arrivals in India, including factors such as historical trends, seasonality, and economic conditions, is utilized form world bank open data. The ARIMA model will be employed to capture the patterns and correlations within the data, enabling the prediction of future tourist numbers accurately. By adopting this forecasting model, policymakers, tourism authorities, and industry stakeholders can make informed decisions regarding infrastructure development, resource allocation, marketing strategies, and policy formulations. This research aims to contribute to the tourism sector by providing reliable insights into the future trends of inbound tourism in India, facilitating sustainable growth and development in the industry.
Digital economy in Africa: condition and problems of development
Authors:   St. Petersburg State University, Prikhodko Dmitrii , Sherov-Ignatiev Vladimir ,   St. Petersburg State University
Published: March 2024

Today, much attention is paid to the development of the digital economy in most countries of the world. African countries are no exception. The purpose is to provide a general analysis of the digital economy in Africa and to assess the correlation between the digitalization and the economic growth. As the main research methods, rating and statistical approaches were used to analyze the development of the digital economy in Africa, as well as correlation analysis to identify the relationship between digitalization and economic growth. The hypothesis of the significance of digitalization as a factor in the economic growth of African countries is being tested. The results confirmed the hypothesis only partially. It was found that for most African states, such a relationship exists and varies depending on the country from medium (Senegal, Cameroon, Tunisia) to very strong (Morocco, Rwanda, Kenya). At the same time, there is a whole group of countries, for which digitalization and economic growth are poorly interconnected. Ranking African countries according to the degree of interconnection between digitalization and economic growth should be the basis for further research in order to determine the place of digitalization in a number of factors of economic growth and development. The article identifies key problems in the development of the digital economy on the continent, including limited access to electricity, the low level of development of the Internet infrastructure, the gender gap in the use of digital technologies, as well as the insufficient level of funding for digital transformation.
A study on brand competitiveness: A comparative analysis of European and Korean auto brands in the Russian automotive industry
Authors:   Peoples’ Friendship University of Russia named after Patrice Lumumba, Lee Han-Sol , Chernikov Sergey ,   Peoples’ Friendship University of Russia named after Patrice Lumumba, Degtereva Ekaterina ,   Peoples’ Friendship University of Russia named after Patrice Lumumba, Zobov Alexander ,   Peoples’ Friendship University of Russia named after Patrice Lumumba
Published: March 2024

This study compares brand competitiveness of European and Korean auto brands in the Russian automotive market based on cross-sectional datasets for 42 auto brands in Russia of the year 2022. The econometric models (OLS, WLS, and Robust least squares) are constructed by employing a theoretical frame of Porter’s diamond model. The results of the regression analysis allowed us to get to the conclusion that product diversification, accessibility to dealers (or retail shop) and active social media marketing are critical factors to promote auto sales in the Russian market. Based on the comparison, we can draw two important conclusions. First, Korean auto brands are ahead of the European auto brands in value chain management as they have a huge pool of dealers and maximize contact with potential Russian customers. Secondly, the German auto brands lead when it comes to product diversification and social media marketing. However, Korean auto brands are not behind based on those criteria compared to the average European auto brand, and take an above average-middling position. From the outstanding performance of Korean auto brands in the Russian market especially, it seems that securing numerous retail channels is particularly crucial. The results of this study are helpful for national and international automotives companies to create business strategies in the Russian automotive industry.
Nankai school: The experience of adapting economics to Chinese conditions in the 1920s–1930s
Authors:   Institute of China and Contemporary Asia of the Russian Academy of Sciences, Borokh Olga
Published: March 2024

Using the example of the activities of the Nankai Institute of Economics in the second quarter of the twentieth century, the article analyses the problem of adapting Western economic theories to the study of the Chinese economy. At the heart of the program of sinicization of economic research and education proposed by the Nankai school was the work of collecting and systematising reliable information on the Chinese economy. In the second half of the 1920s, Nankai University became a leader in China in conducting socio-economic surveys, compiling index numbers of prices, studying selected industries and rural regions. The founders of the Nankai school. He Lian and Fang Xianting were educated in economics in the United States; up until the late 1940s, the Nankai Institute of Economics was highly dependent on American grant support. This did not prevent them from setting the objectives of “knowing China” and “serving China” by combining foreign theories and methods with an understanding of the real economic situation based on reliable quantitative data. The task of “localization” of economics stimulated writing of pioneering university textbooks that explained general theoretical concepts through Chinese examples. Focus on solving China’s problems led the economists to abandon copying ready-made foreign prescriptions. During the two decades of activity in the Republican period the Nankai school made major achievements in collecting factual material on Chinese economy and adapting courses, its legacy has become an important starting point of the contemporary policy of sinicization of economics in the PRC.
EXAMINING THE EFFECTS OF CONNECTIVE TISSUE MASSAGE ON PAIN AFTER THORACOTOMY - RANDOMIZED CONTROLLED TRIAL
Authors: Temel Aksu Neriman , Erdoğan Abdullah
Published: March 2024

Purpose: The objective was evaluate the effect of a connective tissue massage on pain, applied analgesic amounts and length of hospitalization of the patients.
Method: The study was a prospective, randomized, controlled clinical trial and conducted at a thoracic surgery department of university hospital. The patients were randomly allocated to 1 of 2 groups: a control group (n=27) and the experimental group (n=27). Standard medical treatment, care and pulmonary rehabilitation program were applied to both groups. In addition, a total of 5 sessions of connective tissue massage were applied to the experimental group. Pain level of the patients was evaluated at every 24 hours as of the zeroth postoperative day. VAS was used as a one-dimensional scale for pain assessment. Totally applied analgesic amounts and length of hospitalization of the patients were recorded.
Results: There was no statistically significant difference between the experimental and control groups on the postoperative 0th and 1st days. A statistically significant difference was found between VAS averages on postoperative 2nd, 3rd, 4th, 5th, 6th and 7th days (p
Cryptosporidium spp. and Eimeria spp. (Apicomplexa: Eimeriorina) of freshwater Cyprinid fish species in the Kura River basin in Azerbaijan territory
Authors: Mamedova Simuzer , Karanis Panagiotis
Published: March 2024

This study aims to determine the prevalence of Cryptosporidium and Eimeria spp. oocysts in fish specimens in the river Kura. It was conducted during the 2021–2022 at two sites: Mingachevir reservoir in central Azerbaijan and in Neftchala district where the river finally enters the Caspian Sea through a delta of the Kura River estuary. The diagnosis of oocysts was performed microscopically. Fine smears from the intestine epithelial layers stained by Ziehl-Neelsen for Cryptosporidium oocysts. To identify Eimeria oocysts, each fish's faecal material and intestinal scrapings were examined directly under a light microscope in wet samples on glass slides with a coverslip. Results revealed a prevalence of Cryptosporidium and Eimeria species infections in fish hosts from both territories Rutilus caspicus, Alburnus filippi, Abramis brama orientalis and Carassius gibelio. Of 170 investigated fish specimens, 8.8% (15/170) were infected with Cryptosporidium species oocysts. Eimeria species oocysts were identified in 20.6% (35/170). The presence of Cryptosporidium and Eimeria infections in fish specimens are natural infections. However, their presence in fish species may be attributed to the age of the fish species and water pollution. This is the first report regarding the prevalence of Cryptosporidium oocysts in fish species in Azerbaijan.
Spatial assessment of groundwater quality for drinking In Souk El Arbaa, Morocco
Authors: Ghachoui Elhassan , Taouil Hamid , Naser Ramzy S. M. , Said Ibn Ahmed
Published: March 2024

Morocco is facing challenges with its water resources due to population growth, industrial expansion, agriculture, urban development, tourism, climate change, overuse of underground water sources, and pollution from inadequate sanitation and chemical fertilizers. The Gharb aquifer is significant for supplying drinking water and irrigation in the country. Souk El Arbaa is a Moroccan city located in the northwestern part of the Kingdom of Morocco in the Kenitra Province. Its economic activities depend mainly on agriculture and livestock raising. This study aims to assess the groundwater status of a basin in a semi-arid climate in the Souk El Arbaa for drinking purposes by collecting 14 samples in 2022 from different locations and analyzing their physicochemical characteristics. The quality assessment was made by estimating electrical conductivity, pH, total dissolved solids, total hardness, calcium, magnesium, sodium, potassium, bicarbonates, chloride, sulfate, nitrate, and ammonium. The results showed that most of the groundwater in the study area is very hard, and all groundwater in the study area, according to the Moroccan Standards for drinking purposes, exceeds the permissible limits for nitrate and ammonium.
Ultrasonographically Measured Rectus Femoris Cross-sectional Area might
Predict Osteosarcopenia
Authors: Binay Safer Vildan , Catikkas Nezahat Muge , Bas Suleyman , Sevindik Gunay Deniz , Durak Ayfer , Utku Irem Kirac , Safer Umut
Published: March 2024

Aim:

We have aimed to investigate the role of ultrasonographic muscle parameters (UMP) in predicting osteosarcopenia in bedridden patients in a
palliative care center.

Background:

The role of ultrasound has not been evaluated in predicting osteosarcopenia.

Objective:

Reduced muscle thickness (MT) and cross-sectional area (CSA) have often been observed in individuals with sarcopenia, reflecting muscle loss
and atrophy. Meanwhile, the potential role of muscle ultrasound has not been evaluated in predicting osteosarcopenia.

Methods:

We have conducted a prospective, observational study between January 2021 and 2022. We have recorded the demographics, comorbidities, and
nutritional status by using the mini nutritional assessment-short form. We measured handgrip strength with a hand dynamometer and the muscle
mass with dual X-ray absorptiometry. Sarcopenia was defined by the European Working Group on Sarcopenia in Older People 2 criteria.
Osteoporosis was diagnosed according to the World Health Organization criteria. We have categorized the body phenotypes into four groups:
"non-sarcopenic non-osteoporotic," "sarcopenic alone," "osteoporotic alone," and "sarcopenic osteoporotic." We have measured the subcutaneous
fat thickness (SFT), MT, and CSA of the rectus femoris (RF) and biceps brachii (BB) via ultrasonography. A multivariate regression analysis was
performed and area under curve (AUC) values were used to evaluate the accuracy of UMPs.

Results:

We included 31 patients (mean age: 74.6±12.1 years, 54.8%: male). The prevalences of sarcopenia, osteoporosis, and sarcopenic osteoporosis were
71%, 48.4%, and 41.9%, respectively. Only the "sarcopenic osteoporotic" phenotype was negatively correlated with all UMPs. In the regression
analysis, only the "sarcopenic osteoporotic" phenotype was independently associated with RFCSA (ß=-0.456, p= 0.024). The AUC for all patients
was >0.700.

Conclusion:

RFCSA measurement might be useful in the screening for osteosarcopenia. This has been the first study investigating the relationship between
UMPs and body phenotypes. Multi-center and large-scale studies are, however, needed.
Liposomal Nano-Based Drug Delivery Systems for Breast Cancer Therapy: Recent
Advances and Progresses
Authors: Yazdan Mostafa , Naghib Seyed Morteza , Moepubi M. R.
Published: March 2024

Breast cancer is a highly prevalent disease on a global scale, with a 30% incidence rate among women
and a 14% mortality rate. Developing countries bear a disproportionate share of the disease burden, while countries
with greater technological advancements exhibit a higher incidence. A mere 7% of women under the age of
40 are diagnosed with breast cancer, and the prevalence of this ailment is significantly diminished among those
aged 35 and younger. Chemotherapy, radiation therapy, and surgical intervention comprise the treatment protocol.
However, the ongoing quest for a definitive cure for breast cancer continues. The propensity for cancer stem
cells to metastasize and resistance to treatment constitute their Achilles' heel. The advancement of drug delivery
techniques that target cancer cells specifically holds significant promise in terms of facilitating timely detection
and effective intervention. Novel approaches to pharmaceutical delivery, including nanostructures and liposomes,
may bring about substantial changes in the way breast cancer is managed. These systems offer a multitude of
advantages, such as heightened bioavailability, enhanced solubility, targeted tumor destruction, and diminished
adverse effects. The application of nano-drug delivery systems to administer anti-breast cancer medications is a
significant subject of research. This article delves into the domain of breast cancer, conventional treatment methods,
the incorporation of nanotechnology into managerial tactics, and strategic approaches aimed at tackling the
disease at its core.
Food Color, Taste, Smell, Culinary Plate, Flavor, Locale, and their Impact on Nutrition: Present and Future Multisensory Food Augmentation and Noncommunicable Disease Prevention: An Overview
Authors: Wilson Douglas W. , Meester Fabien De , Takahashi Toru , Singh Ram B. , Buttar Harpal S.
Published: March 2024

Cognizant that 'the world is one family', this overview describes
chemosensory characteristics of food and related issues that may enable global
inequalities in healthy food consumption to be improved with a reduction in noncommunicable diseases (NCDs), preventatively. Past and modern aspects of food
tradition are briefly described followed by titular chemosensory characteristics and
their potential application to improving health in nutrition in the sense intended,
including the culinary plate. Human-computer interface and food augmentation reality
and commensal dining, in association with chemosensory properties, including sound
concerning oral food processing, are described. Future research on arresting trends in
the prevalence of NCD is suggested based on the literature. Visual cues for in-store
food choice are discussed that potentially allow the consumer, through psychological
processes and behavior outcomes, to be more discerning. Advertisements and store
architecture per se are not discussed. The relatively high prevalence of anosmia caused
by COVID-19 infection relative to non-infected subjects may alter taste and flavor
perception and lead to changed dietary habits and metabolism. Most global consumers
can practice the 'how' and ‘when’ to beneficially eat but food insecurity poses a global
problem.
Therapeutic Scope and Application of Mushroom-Derived Pharmacoactives in Enhancing Health
Authors: Rajasekharan Pillai Sharika , Chuchawankul Siriporn
Published: March 2024

In the present era, the notion that “prevention is better than cure” has gained
impetus with increased incidences of infectious and degenerative lifestyle diseases.
Recent years have seen many people choosing functional food such as probiotics,
plant-based nutritional supplements, and their normal dietary needs. Studies have
shown significant health benefits in using these nutraceuticals as they aid in the body's
general well-being. Among food varieties, edible mushrooms have also become a
functional dietary food. It has been used as a source of nutrition in many parts of the
world. Oriental medicine has been using mushrooms as a component in various
medicinal concoctions for several decades. Today, with the advent of scientific knowhow, around 2,000 edible mushrooms have been identified; among them, 700 possess
bioactive compounds. Both In vitro and In vivo studies have shown immunomodulatory
effects via the regulation of innate, complement-mediated, and adaptive immunity by
enhancing the active mechanisms of immune systems such as the macrophages, IL,
TNF-α, IFN-γ, NO, and the complement system. The possibility of modulating these
immune system players by the bioactives may pave the way to side-effect-free
anticancer and immunosuppressant drugs. Recent studies have also elucidated the
neuroprotective effect induced by mushroom-derived compounds through ROS
scavenging and antioxidant activity. This chapter highlights the recent findings and the
importance of these mushroom-derived compounds and their anti-inflammatory, anticancerous antioxidant, and immunomodulatory roles.
Immunomodulating Botanicals: An Overview of the Bioactive Phytochemicals for the Management of Autoimmune Disorders
Authors: Thakkar Ami P. , Vora Amisha , Buttar Harpal S. , Kaur Ginpreet
Published: March 2024

Immunomodulation refers to the mechanism by which the response of the
immune system is modified by the regulation of antibody synthesis, leading to either an
increase or a decrease in its levels in the circulation and body organs. Owing to their
immunomodulation and remedial benefits, a broad range of herbal remedies have been
shown to be effective in the treatment of autoimmune diseases such as multiple
sclerosis, rheumatoid arthritis, myasthenia gravis, and systemic lupus erythematosus.
The ancient Indian system of Ayurveda and different other alternative therapeutic
methods have acknowledged the potential benefits of herbal-based remedies to
upregulate or suppress the immune response in the human body. The conventional
pharmacotherapies used for the management of autoimmune ailments are documented
to cause serious drug-induced adverse reactions (ADRs). Whereas, some
phytotherapies have proven safe, reliable, and efficient alternatives for the existing
drug regimens with lesser ADRs. For instance, Withania somnifera, Andrographis
paniculate, Tinospora cordifolia, Glycyrrhiza glabra, and Berberis arista are a few
herbs whose bioactive phytoconstituents have been reported to possess powerful
immunomodulation properties. Based on their purported immunomodulatory
mechanisms, they can be used for the management of autoimmune conditions. The
focus of this review is to highlight the key inflammatory biomarkers such as TNF-α
and interleukin 1, 6 involved in the distortion of the immune system in humans. Also,
we will discuss the usefulness of animal models for understanding the underlying
mechanisms of autoimmune disorders. In addition, we will describe the patents of
phytomedicine formulations filed by different manufacturers for the management of
autoimmune disorders, as well as futuristic opportunities that should be explored for
discovering the therapeutic functions of alternate remedies for treating autoimmune
diseases.
Establishment of Universiti Muhammadiyah Malaysia (UMAM) in the perspective of communication for development through education modernization
Authors: Amallah Nurlaillah Sari , Bakti Andi Faisal , Praptiningsih Novi Andayani , Sanjaya Makroen , Hermansah Tantan
Published: March 2024

Muhammadiyah is considered a radical conservative movement among the Malaysian Muslim community. The education system in Malaysia is generally exclusive. The majority of Malaysian society is resistant to the Muhammadiyah sect except in certain states. This research used the theory from Servaes and Malikhao, the modernization paradigm that influenced academia from 1945 to 1965 was supported by the transition of socio-political technology and culture from advanced societies to traditional societies. Development is explained as economic growth. The main idea in the modernization perspective shows that development is interpreted as first, planned, and overlapping. The results showed ideologically, the principle of progressive Muhammadiyah in establishing Universiti Muhammadiyah Malaysia (UMAM) cannot be separated from the role of the 47th Muktamar Muhammadiyah in Makassar. The congress was aimed at strengthening Muhammadiyah's Islamic vision, namely progressive Islam. Muhammadiyah launched an internationalization program, especially in the field of education, one of its implementations was by developing excellent educational centers abroad. Furthermore, Malaysia is considered the first step as a representative city center that excels in education and internationalization. Muhammadiyah is a movement that cares about Muslims so that they are not degraded by the progress of other nations, so public schools were founded and eventually became universities. This research concluded that the establishment of UMAM was a place to prove that Muhammadiyah is a progressive da'wah movement and builds society towards enlightenment. UMAM presents a superior lecture system with international standards through the use of technology. However, life is still based on Islamic values.