bluuebunny/crossref_metadata_2025 huggingface dataset:
Организация проведения экспертизы продовольствия за счет поставщика
Authors: Ананьин П.А. , Новичкова Ю.Г.
Published: February 2024

Экспертиза в соответствии с законодательством обязательная процедура, которую должен выполнять каждый заказчик. Проводить еѐ может заказчик различными способами, которые и будут проанализированы в настоящей статье.
Споры, возникающие из договора контрактации
Authors: Бондаренко А.Е.
Published: February 2024

В статье рассматривается вопрос о том, какова сущность правоотношений, возникающих между сторонами договора контрактации, а также о субъектном составе данных правоотношений, что позволяет сделать выводы о том, к компетенции какого суда будет отнесено рассмотрение споров, возникающих из договора контрактации. Для разрешения вопроса о том, каике споры подсудны арбитражному суду, в статье также рассматриваются критерии, которые позволяют определить круг рассматриваемых им дел.
Правовой режим особо охраняемых природных территорий: проблемы и особенности
Authors: Добудько В.А.
Published: February 2024

В данной статье раскрываются проблемы и особенности такого объекта экологоправовой охраны, как особо охраняемые природные территории. Автором делается краткий анализ действующего законодательства в указанной области, а также акцентируется внимание на спорных положениях, связанных с регулированием режима правовой охраны указанных территорий. В конце делается вывод о важности установления правовой охраны и ее роли в процессе обеспечения защиты окружающей среды на уровне государства.
Субъект преступлений против семейных ценностей
Authors: Дранович А.Е.
Published: February 2024

Статья посвящена понятию субъекта преступлений против семейных ценностей. С целью подробного рассмотрения основ субъекта преступлений против семейных ценностей необходимо понять, что же подразумевают под собой понятие «субъект уголовного преступления». Под субъектом уголовного преступления понимается физическое лицо, которое совершило преступление (действие или бездействие) и может нести за это уголовную ответственность. Важность определения субъекта преступления перед возбуждением уголовного дела заключается в том, что именно субъект преступления является ответственным лицом, которое должно нести наказание за совершенное противоправное деяние. Определение и достоверное установление личности субъекта преступления является одним из первоочередных задач следствия, так как от этого зависит правомерность и законность применяемых мер по расследованию преступления.
Право на свободу совести и вероисповедания в России эпохи буржуазнодемократических революций
Authors: Кривова А.А. , Ирицян В.А.
Published: February 2024

В статье говорится о праве на свободу совести и вероисповедания в России эпохи буржуазно-демократических революций. Выделяются исторические события и значимые даты, связанные с этим. Затрагиваются исторические документы которые говорят о данном праве. Говорится об изменении, дополнении и внесении поправок к законам о свободе совести, в которых перечислялись новые положения, нормы и права граждан, связанные с правом на свободу совести и вероисповедания. Упоминались основные принципы государственного права Российской Империи и в них же выделялось особо важное значение свободы совести и вероисповедания граждан в России. Рассматривались элементы концепции свободы совести. На протяжении всей работы выделяется важный исторический документ "Справка о свободе совести". Говорилось о том, что выносились предложения членами Государственной Думы о поправках и введении новых положений в закон о свободе совести и вероисповедания. В статье говорилось о том, что чтобы реализовать свободу совести в России-необходимо признать еѐ. Также говорилось о составлении нового законопроекта, касающегося свободы совести и вероисповедания.
Смертная казнь: «за» или «против»?
Authors: Панькова А.Ю.
Published: February 2024

В настоящем исследовании анализируются аргументы «за» и «против» смертной казни, зарубежный опыт применения смертной казни. Автор в заключении статьи объясняет собственное отношение к необходимости отмене моратория на применение в качестве высшей меры уголовного наказания смертной казни, рассматривает пути разрешения данного вопроса.
Запрет на приближение и запрет определенных действий: вопросы правового регулирования
Authors: Рябова О.А. , Рябов П.Р.
Published: February 2024

Авторы статьи анализируют законопроект, содержащий поправки в Гражданский кодекс РФ, касающиеся ограничения определенных действий и запрета на приближение. Названные поправки по задумке авторов законопроекта должны стать одной из форм защиты прав и свобод человека и гражданина от преследования со стороны других лиц. Авторами указывается на актуальность и своевременность данной законодательной инициативы. При этом обращается внимание на необходимость комплексного подхода к реализации законопроекта во взаимосвязи его с нормами процессуального права с целью эффективной реализации с одной стороны и недопущения злоупотребления правом с другой.
Влияние возрастного фактора мужчин на показатели спермограммы
Authors: Иванова О.С. , Исмаилов Т.К. , Турлыбекова Г.К.
Published: February 2024

В статье проведено ретроспективное исследование спермограмм 665 мужчин г. Караганды, где проанализировано влияние возрастного фактора на такие микроскопические характеристики эякулята как концентрация сперматозоидов в 1 мл, доля прогрессивноподвижных и морфологически нормальных сперматозоидов с целью установления зависимости фертильной функции на основе качества эякулята от возраста мужчин.
Показатели здоровья детского населения города Уфа в зависимости от места проживания и pH водопроводной воды
Authors: Каплина Г.К. , Тельцова Л.З. , Валеев Т.К.
Published: February 2024

На сегодняшний день следует уделять особое внимание здоровью детского населения, проживающего на территории крупных городов-миллионников в связи с выходом на первый план все нарастающей демографической проблемы. Известно, что здоровье человека определяется сложным воздействием целого ряда факторов — наследственность, образ и качество жизни, а также качество окружающей среды. В данной статье приведен анализ pH водопроводной воды на территории двух административный районов города Уфы – Демского и Октябрьского, а также биохимический анализ крови детей дошкольного возраста проживающих там.
Химические добавки и их влияние на свойства бетона
Authors: Курников Т.Д. , Тлехусеж М.А.
Published: February 2024

В статье рассматривается влияние химических добавок на бетон, уделяется внимание химии и строительным аспектам. Обсуждаются различные типы добавок – пластификаторы, ускорители, замедлители твердения, их химические особенности и механизмы воздействия на бетон. Освещается экономическая эффективность и экологическая безопасность применяемых добавок. Предложен интегрированный подход к их выбору и использованию с учѐтом технических и экологических требований.
Физическая культура как регулятор психологического состояния студентов
Authors: Гусев П.М. , Хайруллина А.М. , Нуриева Л.И.
Published: February 2024

В данной статье рассматривается роль физических нагрузок в регулировании психологических процессов и улучшении эмоционального состояния студентов. В процессе обучения, особенно, в экзаменационный период, студенты подвергаются большой эмоциональной нагрузке, что неблагоприятно сказывается на общем состоянии нервной системы. Физическая культура и спорт выступают значимым фактором стабильного психологического состояния, положительно сказываясь на всех его процессах. Студентам необходимо уделять время на физические нагрузки, дабы уменьшить неблагоприятное воздействие стрессовых ситуаций и улучшить свою работоспособность.
Влияние физической культуры и спорта на здоровье студентов в вузе
Authors: Ибрагимов И.Ф. , Фаттахова К.И.
Published: February 2024

В статье «Влияние физической культуры и спорта на здоровье студентов в вузе», автор рассматривает основные преимущества от занятий спортом на организм учащихся в университете. Целью статьи является определение значимости физической культуры и спорта для здоровья студентов. Задачей работы стало выявление преимуществ от занятий спортом для учащихся вузов. Методы исследование: анализ тематической литературы, анкетный опрос. Результатом исследование явилось определение того, что физическая активность оказывает влияние на физическую подготовку, психическое здоровье, лидерские и социальные навыки, лидерскую успеваемость и личностный рост обучаемых. Были сделаны следующие выводы: регулярная физическая активность снижает риск возникновения ряда заболеваний, спорт и игры приносят пользу для физического здоровья, а также дают прекрасную возможность развить социальные навыки.
Efficacy and Safety of Insulin Degludec/Insulin Aspart versus Biphasic Insulin Aspart 30 in Patients with Type 2 Diabetes: A Meta-Analysis of Randomized Controlled Trials
Authors: Niu Yan-Li , Zhang Ye , Song Zhi-Yong , Zhao Chuan-Zhi , Luo Yun , Wang Yan , Yuan Jing
Published: February 2024

Background: We systematically reviewed and analyzed the efficacy and safety of insulin degludec/insulin aspart (IDegAsp) versus biphasic insulin aspart 30 (BIAsp 30) in patients with type 2 diabetes (T2D).
Methods: We used computers to search the Embase, PubMed, Clinical Trials, and the Cochrane Library database, and collected randomized controlled trials (RCTs) on the treatment of IDegAsp versus BIAsp 30 in T2D patients. The research period was from the establishment of the database to May 19, 2023. We used Review Manager 5.20 statistical software for systematic meta-analysis.
Results: We included 8 RCTs with 2281 participants. IDegAsp was better to BIAsp30 in improving fasting plasma glucose (FPG) levels (P<0.001) and reducing the endpoint daily average insulin dose (P<0.01). Furthermore, compared with BIAsp30, IDegAsp significantly reduced the risk of nocturnal hypoglycemic events (P<0.001). However, there was no significant difference in the improvement of body weight change (P=0.99), glycosylated hemoglobin (P=0.50), the overall risk of hypoglycemic events (P=0.57) and adverse events (P=0.89) between the two groups.
Conclusion: Compared with BIAsp30, IDegAsp could significantly reduce FPG levels, insulin dosage, and the risk of nocturnal hypoglycemic events in T2D patients, without increasing the overall risk of adverse events.
Development of Reference Point of Doping Attitude and Dispositions for Anti-Doping Education Notification of Athletes: Application of Reference Group Model
Authors: Jeon Minsoo , Oh Hyeri , Lim Hyosung , Yun Hyo Jun
Published: February 2024

Background: We developed a reference point by applying a doping attitude and propensity tool to prevent doping in sports athletes.
Methods: Performance Enhancement Attitude Scale (PEAS) was investigated on 768 registered athletes with the Korea Sports Association. Independent sample t-test and ANOVA were applied to confirm the doping attitude and propensity according to anti-doping education and event type. To establish the criteria for PEAS, the intersection was confirmed through the group comparison method, and EasyOZ by Excel was applied at this time. In addition, accuracy, sensitivity, and specificity were calculated to confirm the validity of the reference point.
Results: First, in the case of anti-doping education, it was confirmed that more than 90% of the anti-doping education was completed in all sports. Second, there was no statistically significant difference in PEAS according to the type of sport, and there was only a difference in the PEAS according to whether or not anti-doping education was provided and whether or not there was anti-doping education. Third, the point of contact established in the group comparison method was 29.5 points, and as a result of validating the validity based on this, 30 points were found to be the most suitable index.
Conclusion: This study could be used as important information in that it suggests a different method for evaluating PEAS and establishes a reference point that can be used more effectively in the actual field.
Evaluating the Causal Effects of Low Density Lipoprotein Cholesterol Levels on Ischemic Stroke: A Mendelian Randomization Study
Authors: Hou Xiaowen , Zheng Jiaqi , Zhang Jiajun , Tao Lin , Cen Kaiwen , Cui Ying , Wu Ji
Published: February 2024

Background: Ischemic stroke (IS) is the leading cause of disability and mortality worldwide. Low-density lipoprotein cholesterol (LDL-C) levels hadno potential risk on ischemic stroke. However, higher LDL-C levels were closely related to IS. Based on two antagonistic viewpoints, a Mendelian randomization (MR) study was designed to evaluate the causal effects of LDL-C levels on IS.
Methods: Datasets of LDL-C levels and ischemic stroke were acquired from genome-wide association studies (GWAS). Weighted median method was conducted for main analysis, and MR-Egger and inverse-variance weighted (IVW) methods were performed for auxiliary analyses. Heterogeneity and pleiotropic tests were utilized to confirm the reliability of this study.
Results: A total of 359 single nucleotide polymorphisms (SNPs) were associated with LDL-C levels (P < 5 × 10−8) and 337 SNPs were available in ischemic stroke with eliminating outliers. LDL-C levels were significantly associated with ischemic stroke (OR = 1.104, 95%CI = 1.019 - 1.195, P = 1.52 × 10-2). MR-Egger and IVW showed directionally similar estimates (MR-Egger: OR = 1.120, 95%CI = 1.040 - 1.207, P = 3.12 × 10-3; IVW: OR = 1.120, 95%CI = 1.064 - 1.178, P = 1.17 × 10-5).
Conclusion: LDL-C levels had causal effects on IS, providing insights into the design of future interventions to reduce the burden of ischemic stroke.
Evaluation of Immunohistochemical Expression of Survivin and its Correlation with qRT-PCR Results as a Useful Diagnostic Marker in Gastric Cancer
Authors: Fanaei Khadijeh , Ameli Fereshteh , Salahshourifar Iman , Irani Shiva , Esfandbod Mohsen
Published: February 2024

Background: Today, survivin is known as one of the most specific cancer proteins; provide unique and practical study opportunities. Clinical value of survivin in gastric cancer (GC) is not yet appointed. To establish the expression level of survivin and its diagnosis value in Iranian patients with GC, we evaluated the association of survivin expression with clinicopathologic factors.
Methods: Overall, 60 matched-normal controls with 60 GC samples including 30 cases with evidence of metastasis at time of our study and 30 cases without evidence of metastasis were recruited, in Tehran, Iran during 2008 to 2018. Survivin expression was evaluated by quantitative Real-time polymerase chain reaction (qRT-PCR) and immunohistochemistry (IHC) study.
Results: Increased expression of survivin at mRNA and protein levels was found in 86.7% and 71.6% of cases, respectively. Evidence indicated a significant difference in survivin mRNA expression level between tumor and non-tumoral (marginal) tissues (P<0.001). The difference in expression of survivin mRNA was not significant between metastatic and non-metastatic tumor tissues (P=0.171). Positive immunoreactivity of survivin was observed to be predominantly in the nucleus of tumor cells. A significant difference in survivin protein expression was detected between tumor and non-tumoral tissues (P<0.001) and between metastatic and non-metastatic tumor tissues (P<0.001). There was no significant association between survivin mRNA expression and clinicopathological variables. However, survivin protein expression was significantly correlated with perineural involvement (P<0.018).
Conclusion: This data could be supportive of using survivin as a useful diagnostic marker in GC. Although, more research is needed in this area.
Sleep disorders among healthcare workers during the COVID-19 pandemic: An umbrella review and meta-analysis
Authors: Tahernejad Somayeh , Ghaffari Sina , Farahmandnia Hojjat , Farahi-Ashtiani Iman , Sahebi Ali , Tahernejd Azadeh
Published: February 2024

Background & Aim: Healthcare workers are at the forefront of the fight against COVID-19 and are exposed to numerous risks and health consequences, including sleep disturbance. The present study aimed to investigate the prevalence of sleep disorders among HCWs during the COVID-19 pandemic using an umbrella review of meta-analyses.
Methods & Materials: Based on the guidance of PRISMA, literature was searched on the Web of Science, PubMed, Embase, Science Direct, Scopus, and Google Scholar (from the beginning of January 2020 to the end of March 2022). The random effects model was used for meta-analysis, and the I2 index was employed to ascertain heterogeneity among studies. Publication bias was investigated using the Begg test. Data were analyzed using STATA software version 14.
Results: Initially, 561 studies were found after the primary literature search in the data resources, of which 27 eligible studies were selected for quality assessment and data extraction. The results showed that the prevalence of sleep disorders among HCWs during the COVID-19 pandemic was 38.27% (95% CI: 35.20-41.01, I2= 74.2%, P= 0.008).
Conclusion: Based on the results of this review, the prevalence of sleep disorders among HCWs during the COVID-19 pandemic was relatively high. Therefore, these individuals should undergo routine screening for sleep quality and other mental health disorders.
Barriers to adopting evidence-based practice: A cross-sectional study among undergraduate nursing students in Vietnam
Authors: Hien Pham Thi Thu , Thuy Luu Thi , Yen Hoai Nguyen Thi
Published: February 2024

Background & Aim: As the future nursing workforce, evidence-based practice is one of the key competencies for undergraduate nursing students in delivering safe and quality care. While plenty of studies investigate nurses' evidence-based practice, understanding this topic is limited among nursing students. Thus, this study aimed to identify barriers and associated factors to adopting evidence-based practice among undergraduate nursing students in Vietnam.
Methods & Materials: A cross-sectional descriptive study was conducted on 395 undergraduate nursing students who were conveniently selected at a public university in Central Vietnam from March to May 2022. A questionnaire was administered to collect information about general characteristics and barriers to implementing evidence-based practice regarding knowledge, practice, authority, setting, and research utilization. Data were analyzed using SPSS 20.0 with descriptive statistics, independent T-test, one-way analysis of variance, and Pearson's correlation coefficients.
Results: Among 395 participants, most of them faced barriers regarding knowledge (91.9%), practice (96.2%), authority (89.1%), clinical setting (92.2%), and research utilization (96.2%). The most mentioned barriers were related to research utilization and clinical settings. Barriers to adopting evidence-based practice were significantly associated with a level of seeking information about research/scientific evidence and a level of participating in research/implementing evidence-based practice (p<.05). Moreover, knowledge barriers were related to age, school year, and sources of data for searching (p<.05).
Conclusion: Undergraduate nursing students have faced many barriers when adopting scientific evidence into clinical practice. Supporting students in addressing these barriers is necessary to enhance their evidence-based practice competency.
MOLECULAR GENETIC CHARACTERIZATION OF UKRAINIAN REPRESENTATIVES OF THE COMPLEX SPECIES ACONITUM ANTHORA BASED ON THE ITS1-5.8S- ITS2 REGION OF THE NUCLEAR GENOME
Authors: Tynkevich Yu. O. , Biliai D. V. , Cherevatov O. V. , Kagalo O. O. , Volkov R. A.
Published: February 2024

Problem. The question of determining the boundaries of a species, in addition to the fundamental aspects, is of practical importance for nature conservation activities. One of the taxonomically problematic groups is the complex species A. anthora s. l. In the flora of Ukraine, four taxa with controversial status are distinguished within its borders, A. anthora L., A. eulophum Rchb., A. jacquinii Rchb. and A. pseudanthora Błocki ex Pacz. The last two species are included in the Red Book of Ukraine and the IUCN list. Determining the taxonomic position of these closely related forms requires the use of molecular genetic approaches. The ITS1-5.8S-ITS2 region of 35S rDNA is considered the most popular and informative marker for plant taxonomy and barcoding.
Aim. To clarify the taxonomic status and phylogenetic relationships of representatives of A. anthora s. l. using the molecular marker ITS1-5.8S-ITS2 of 35S rDNA.
Methods. Herbarium specimens of four representatives of the group A. anthora s. l. were collected on the territory of Western Ukraine. DNA was isolated by a modified CTAB method and then used for PCR amplification of the ITS1-5.8S-ITS2 region. PCR products were purified and Sanger sequenced. The sequences obtained were aligned with the sequences deposited in the GenBank database for representatives of two subgenera of the genus Aconitum, i.e. the nominative subgenus and the subgenus Lycoctonum. The resulting matrix was used for principal component analysis (PCA) and phylogenetic analysis using the Maximum Likelihood method.
Main results. The sequences of ITS1-5.8S-ITS2 that we obtained for A. anthora, A. eulophum, A. jacquinii, and A. pseudanthora samples were found to be almost identical. They differed from each other in only five of the 641 alignment positions. Among them, four out of five positions appeared to be polymorphic even within individual genomes. According to the results of PCA analysis, all four samples of A. anthora s. l. formed a dense cluster separated by significant distances from the clusters formed by representatives of the subgenera Aconitum and Lycoctonum. In the generated phylogenetic tree, three main monophyletic clades are present, which correspond to the subgenera Aconitum and Lycoctonum and the A. anthora s. l. group. The Lycoctonum clade was sister to other members of the genus, and the Aconitum and A. anthora s. l. clades were sister to each other.
Conclusions. The use of the ITS1-5.8S-ITS2 region of 35S rDNA for phylogenetic analysis confirms the need to grant the A. anthora s. l. group the status of a separate subgenus within the genus Aconitum. The high genetic affinity between samples of A. anthora s. l. from the territory of Ukraine indicates that the species names A. eulophum, A. jacquinii, and A. pseudanthora should be considered synonyms of A. anthora.
SCIENTIFIC JOURNAL “VOLYNSKYY BLAHOVISNYK”: A SHORT HISTORY ON THE OCCASION OF THE 10th ANNIVERSARY
Authors: Fulmes V. S.
Published: February 2024

The glorious center of spirituality and science in the western lands was the Volyn Theological Seminary, which since its founding in 1796 has educated and graduated a large number of students, including prominent hierarchs of the Church of Christ, devotees of piety, representatives of theology. For a long time in different periods of the seminary’s existence, an important and integral part of its functioning was scientific activity. Improvement of the educational process, intensification of scientific life, development of the infrastructure of theological school led to the reorganization of the Volyn Theological Seminary into the Volyn Orthodox Theological Academy. The status of the Academy has significantly intensified the teaching staff and students to persistent research work with clear objectives: to preserve the traditions of spiritual education, to increase the experience and to integrate into the world educational and scientific space.
The scientific life of any educational institution is unthinkable without its scientific journal, therefore an important event in the life of the Volyn Orthodox Theological Academy was the appearance in 2013 of the theological and historical scientific journal “Volynskyy Blahovisnyk” (VB) in its own publishing house “ΕΙΚΩΝ”. Since the founding of the “Volynskyy Blahovisnyk” (VB) in 2013 and up to today, there have been many changes in the publication of the scientific journal, in particular, the composition of the editorial board and reviewers has significantly increased, to which international scientists have also joined, there have been some changes in the appearance and design of the journal, etc. Every year, each subsequent issue was improved, which made it possible to start indexing in the leading scientific and metric databases and also to be included in the List of scientific specialized publications of Ukraine of category “B” (specialty – 041 Theology).
This article briefly presents information about the history of the establishment of the professional periodical of the Volyn Orthodox Theological Academy “Volynskyy Blahovisnyk” (VB), noted the main events in the development of the scientific publication, which became a platform for the exchange of scientific achievements between science and theology, providing mutual integration and incorporation.
Cultural and Molecular Diversity of Fusarium pallidoroseum (Cooke.) Sacc Isolates Causing Wilt in Mothbean (Vigna aconitifolia)
Authors: Patel D.D. , Waghunde R.R. , Abhishek Dinisha , Garde Y.A.
Published: February 2024

Background: Mothbean is minor pulse crop grown in arid and semi-arid region. Mothbean wilt is one of the most important diseases directly contributing to the yield losses of the crop. It is caused by Fusarium which shows the great cultural, morphological and molecular diversity. Nowadays, the meagre information known mothbean wilt and pathogen causing it. Methods: Present investigation was conducted during 2022-2023, the fixed plot survey was carried out in moth bean growing farmers’ fields of Bharuch district. Eleven isolates of the pathogen were collected from selected villages of Bharuch district. The cultural and morphological characteristics of pathogen were studied under laboratory condition as per standard methods. The molecular variability of eleven isolates causing mothbean wilt was studied employing standard six ISSR primers. Result: During this investigation, the pathogen causing mothbean wilt is new record from South Gujarat location. Eleven Fusarium isolates causing mothbean wilt was found under Bharuch district of Gujarat. The cultural, morphological and molecular characteristics of eleven isolates were studied during present work. The present investigation will explore detailed study of Fusarium isolates causing mothbean wilt and their geographical cultural and morphological characteristics along with molecular diversity.
Lupinus mutabilis Sweet (Tarwi) γ-conglutin Modulates TNF-α and IL-1α Transcriptional Expression in Human Monocytes Infected with Leishmania (V.) peruviana
Authors: Arone-Farfán R. , Alzamora-Gonzales L. , Carnero L.A.R. , Colona-Vallejos E. , Escobar-Guzmán E. , Camarena-Mayta F. , Huaringa-Joaquín A.
Published: February 2024

Background: γ-Conglutin is a hemagglutinating lectin found in the seeds of the Andean legume Lupinus mutabilis. Leishmania (Viannia) peruviana is the etiological agent of cutaneous leishmaniasis, which is endemic in Peru. Leishmaniasis is a neglected disease that lacks an effective and non-toxic treatment. The aim of this study was to evaluate the effect of γ-conglutin from L. mutabilis Patón Grande ecotype (CoPG) on human monocyte cultures before infection with L. (V.) peruviana and to determine the production of molecules that stimulate cellular immunity. Methods: CoPG was isolated by chromatography from a hexane extract of L. mutabilis seeds. Monocytes were obtained by density gradient centrifugation. The effect of CoPG on their viability was determined by the MTT assay. To assess superoxide and nitric oxide production, monocyte cultures were pre-treated with CoPG and then infected with L. (V.) peruviana. Transcriptional expression of TNF-α and IL-1α in CoPG-treated and parasite-infected monocytes was determined by RT-PCR. Result: CoPG retained its hemagglutinating activity throughout the isolation process. The purified protein had a molecular weight of 47 KDa. Besides, CoPG at a 20 µg mL-1 induced the production of superoxide on the treated monocytes. This CoPG concentration also promoted the overexpression of IL-1α and TNF-α on the infected monocytes. The present study showed that CoPG has a novel in vitro immunomodulatory effect. The discovery of bioactive proteins from L. mutabilis may uncover a wide range of new applications for this Andean plant.
Laporan Kasus: Anaplasmosis dan Ehrlichiosis pada Anjing Husky Siberia Penderita Penyakit Ginjal Kronis
Authors: Permatasari Serly Nur Indah , Batan I Wayan , Erawan I Gusti Made Krisna
Published: February 2024

Anaplasmosis dan ehrlichiosis merupakan infeksi yang disebabkan oleh bakteri obligat intraseluler yaitu Anaplasma sp. dan Ehrlichia canis. Pada kasus ini, dilaporkan terjadi pada anjing husky siberia yang didiagnosis mengalami penyakit gagal ginjal kronis stadium tiga dan rutin dilakukan check up dua minggu sekali. Saat pemeriksaan ketiga anjing tampak lemas, nafsu makan menurun, terdapat leleran mukopurulen di hidung, dan ditemukan caplak. Hasil pemeriksaan fisik menunjukkan kasus hewan mengalami dehidrasi yang ditandai dengan membran mukosa yang pucat dan turgor kulit menurun. Hasil pemeriksaan hematologi rutin menunjukkan kasus anjing mengalami anemia normositik hiperkromik dan trombositopenia. Hasil pemeriksaan biokimia darah menunjukkan peningkatan kreatinin, Blood Urea Nitrogen (BUN), dan Symmetric Dimethylarginine (SDMA). Pemeriksaan ulas darah menunjukkan adanya badan inklusi pada monosit yang kemudian dikonfirmasi hasil positif dengan uji serologi test kit terhadap Anaplasma sp. dan Ehrlichia canis. Diagnosis definitif anjing kasus adalah gagal ginjal kronis stadium 3 disertai anaplasmosis dan ehrlichiosis. Penanganan yang dilakukan adalah pemberian terapi cairan, antibiotik doksisiklin (10 mg/kg BB, selama 28 hari), anti inflamasi metilprednisolon (0,5 mg/kg BB, selama 14 hari), dan pengobatan suportif dengan suplemen herbal Nutrilite® Liver Health with Milk Thistle dan Dandelion Plus diberikan satu tablet sehari sekali dan suplemen ginjal AminAvast® diberikan dua tablet sehari sekali. Setelah hari ke-14 pengobatan menunjukkan perbaikan kondisi yang ditandai dengan nafsu makan yang baik, anjing terlihat aktif kembali, serta bebas dari caplak. Hasil pemeriksaan kimia darah setelah hari ke-14 menunjukkan penurunan nilai kreatinin dan Blood Urea Nitrogen (BUN).
Keefektifan Pembuatan RPP Inovatif, Media dan Weblog Pembelajaran guna meningkatkan Kualitas Pembelajaran di Pondok Pesantren Darussalam
Authors: Jhoni Muhammad
Published: February 2024

The purpose of this service program is to assist madrasa teachers at the Darussalam Islamic boarding school in making Innovative RPP, Learning Media, and Web blogs. The method used is Participatory Action Research (PAR), in which all relevant parties are actively involved in analyzing the stages of ongoing activities in order to make changes for the better. Based on the results of the service, it was found that the average attitude of the teacher was 6.38 for making weblogs, an average of 7.54 for PPT, and an average of 6.97 for RPP, each of which was in the good category.; 86% of the 37 participants were able to make weblogs, PPT, and RPP; each school makes an official school weblog. Thus, it can be concluded that this PKM activity has a good impact on madrasa teachers at the Darusaalam Islamic Boarding School.
A memória institucional do Instituto de Economia
Authors:   Universidade Estadual de Campinas, Alves Rodrigo Coutinho , Silva Matheus Leonardo da Costa ,   Universidade Estadual de Campinas
Published: February 2024

Introdução: Preservar a memória de uma instituição significa garantir o conhecimento sobre a sua fundação, fatos e atores que trouxeram com êxito a organização aos dias de hoje. Desenvolver e apresentar a história institucional é valorizar todos os esforços feitos por seus pioneiros e sucessores e permitir uma reflexão sobre a trajetória da instituição. Objetivo: O projeto “Memória Institucional do Instituto de Economia/UNICAMP” teve como objetivo levantar informações históricas sobre os principais momentos de construção do Instituto de Economia, desde o início de suas atividades e disponibilizá-las de forma simples e organizada para toda a comunidade interna e sociedade. Metodologia: Para garantir o conhecimento e a divulgação da memória do Instituto de Economia/UNICAMP, priorizou-se o resgate de informações através de registros fotográficos e documentos antigos no Instituto, além de grande contribuição do Sistema de Arquivos da Unicamp/SIARQ. Resultados: Os levantamentos de informações, fotos e momentos da história institucional resultaram em duas divulgações disponíveis no portal da Unidade (www.eco.unicamp.br): i) uma linha do tempo dos Diretores do Instituto de Economia; ii) um registro detalhado de fatos históricos da Unidade, incluindo a proposta de funcionamento do Departamento no IFCH/UNICAMP (1968), a proposta de criação do Instituto de Economia (1984) e a inauguração das instalações próprias em 1986. Conclusão: A organização das informações históricas e a publicação em sítio eletrônico da Unidade, impediram o esquecimento dos fatos e promoveram a memória institucional do Instituto de Economia para conhecimento amplo da comunidade atual e de futuras gerações.
Avaliação de egressos de cursos de pós-graduação em biotecnologia: desenvolvimento baseado na metodologia almalaurea
Authors:   Universidade Estadual Paulista, Desiderio Tamiris Mariani Pereira , Ferreira Ana Silvia Sartori Barraviera Seabra ,   Universidade Estadual Paulista
Published: February 2024

Introdução: Com as recentes regulamentações acerca da atuação do aluno egresso da área da saúde este é um momento propício para fomentar ferramentas que auxiliem os programas de Pós-graduação a conhecer o perfil de seus egressos bem como estreitar os laços com o mercado de trabalho Objetivos: Este trabalho tem como objetivo desenvolver uma metodologia de avaliação de egressos do curso de Pós-graduação em Pesquisa e Desenvolvimento (Biotecnologia Médica) da Faculdade de Medicina de Botucatu – FMB Unesp. Metodologia: Inicialmente foi feita uma pesquisa bibliográfica a fim de entender como são avaliados os egressos de cursos semelhantes no Brasil, a partir dos resultados optou-se por implantar um questionário, disponibilizado em um site. Foram estruturadas as interfaces dos egressos, empresas e administrador e a etapa de programação foi feita por uma empresa júnior contratada. A partir dos resultados após análise do grupo piloto serão apresentados modelos preditivos a partir da interação dos alunos com o mercado de trabalho. Esta pesquisa foi submetida e aprovada pelo Comitê de Ética e Pesquisa da Faculdade de Medicina de Botucatu, sob o parecer 613752920.1.0000.5411. Resultados: Como resultado foram apresentados dois artigos o primeiro, Avaliação de egresso da área da saúde: uma revisão. O segundo, Edulink - Desenvolvimento de plataforma de avaliação de egressos com participação do mercado de trabalho exibe o delineamento da elaboração da página. Atualmente apresenta-se também o registro de programa de computador, BR512023001522-9. Conclusões: até o presente momento pode-se concluir que a página está apta para ser encaminhada ao grupo piloto.
A atuação da Biblioteca Antonio Candido do IEL/UNICAMP no enfrentamento da pandemia Covid19 na UNICAMP nos anos de 2020 a 2021
Authors:   Universidade Estadual de Campinas, Araújo Dionary Crispim de , Custódio Crisllene Queiroz ,   Universidade Estadual de Campinas, Santos Cristiano Brito dos ,   https://orcid.org/0009-0006-4539-5407, Nocera Tiago Pereira ,   Universidade Estadual de Campinas, Grego Joyce Catarina ,   Universidade Estadual de Campinas, Nascimento Leandro dos Santos ,   Universidade Estadual de Campinas
Published: February 2024

Introdução: A Biblioteca Antonio Candido foi pioneira no Sistema de Bibliotecas Unicamp (SBU) a apresentar um Plano de Contingenciamento no enfrentamento da pandemia Covid-19. Acompanhamos pelos webinários como as Bibliotecas da Europa estavam atuando no atendimento emergencial. E, deste modo fomos adaptando nosso Plano de Contingenciamento conjuntamente às orientações do SBU. Objetivo: Elaborar ações de atendimento para suprir as necessidades informacionais dos usuários da Biblioteca durante a pandemia. Metodologia: Os serviços atendidos foram: empréstimos mediante agendamento e entrega num sistema take away com uso de EPI na separação do material; prática da quarentena dos livros devolvidos; adoção de teletrabalho pela equipe; atendimento online; elaboração de fichas catalográficas; recebimento de doação de Reserva Técnica; digitalização de capítulos de livros. Realização do preparo e a adaptação dos espaços da biblioteca (sinalizações, bloqueio assentos/equipamentos, readequação do balcão de atendimento) para o retorno presencial da comunidade. Resultados: Os indicadores de serviço e produção foram: Empréstimos: 9379 (A Biblioteca que mais emprestou do SBU); Acessos às Teses/ Dissertações: 1.228.036 downloads; Acesso aos TCCs: 66.003 downloads; Capacitação de usuários: 124; Recepção calouros: 302; Empréstimo entre Bibliotecas: 97 atendimentos e 17 solicitações; Compra de livros de Reserva Técnica: 1.109 livros; Elaboração fichas catalográficas: 280;Redes Sociais: Facebook 2.100 seguidores e Instagram 326 seguidores. Conclusão: Os profissionais da Biblioteca assumiram um compromisso social, incorporando uma postura dinâmica, orientada e antecipada às necessidades informacionais de seus usuários, uma vez que a Biblioteca é o principal suporte acadêmico da pesquisa e do ensino desenvolvidos no Instituto de Estudos da Linguagem.
Adequação das normas e práticas de armazenamento de produtos controlados no Almoxarifado do Instituto de Química da Unicamp
Authors:   Universidade Estadual de Campinas, Yoshinaga Fabiana , Santos Bárbara Leite Tacarambi ,   Universidade Estadual de Campinas, Rosa Isabela Ferreira ,   Universidade Estadual de Campinas, Spoladore Larissa ,   Universidade Estadual de Campinas
Published: February 2024

Introdução: O processo de reformulação de resoluções internas é bastante complexo, pois envolve a mudança da cultura organizacional de uma instituição. Objetivo: O presente trabalho objetivou reformular as normas de armazenamento de produtos químicos controlados no almoxarifado do Instituto de Química da Unicamp. Metodologia: Foram analisadas as resoluções internas que vigoravam no Instituto de Química da Unicamp. A partir desse estudo foram elaboradas adequações de forma a alinhar as normas internas com a legislação nacional e estadual vigentes. Resultados: A resolução proposta foi aprovada na Congregação do Instituto de Química e já está em vigor, trazendo diversas vantagens para a instituição, como o atendimento à legislação vigente para evitar autuações dos órgãos de fiscalização e o aumento da segurança do Almoxarifado e das pessoas que trabalham e/ou frequentam o local. A alteração realizada também suscitou na comunidade interna o debate sobre as legislações vigentes. A ação educativa aconteceu tanto entre docentes, quanto em discentes, os quais poderão, futuramente, propagar os conhecimentos adquiridos em seus locais de trabalho. Conclusão: O trabalho apresentado conseguiu atingir o objetivo proposto. É importante destacar que o processo de reformulação de normas é um trabalho árduo e, por envolver uma mudança cultural, depende do engajamento contínuo da comunidade acadêmica.
Plataforma Sucupira no IFSC-USP: a participação da biblioteca no preenchimento da Produção Intelectual
Authors:   Universidade de São Paulo, Mastrantonio Sabrina Di Salvo , Pepe Gracielli Batista ,   Universidade de São Paulo, Prado Ana Mara Marques da Cunha ,   Universidade de São Paulo, Silva Isabella Cristina Gomes da ,   Universidade de São Paulo, Almeida Tania Ortin de ,   Universidade de São Paulo
Published: February 2024

Introdução/Objetivo: O desempenho dos programas de pós-graduação das universidades brasileiras é avaliado pela CAPES, a qual utiliza a Plataforma Sucupira para coleta de dados (Brasil, 2020). Dentre as inúmeras informações solicitadas, destaca-se o módulo de Produção Intelectual, cujo preenchimento é de difícil execução pelos programas. Nesse contexto, surge a importância da parceria da Biblioteca do IFSC junto ao Serviço de Pós-graduação, no preenchimento dos dados da Produção Intelectual na Plataforma Sucupira, a qual apresentamos neste trabalho. Metodologia: A biblioteca, a partir dos dados extraídos do Dedalus, preenche os dados da Produção Intelectual (Módulo Produções Acadêmicas) e cadastra novos autores na Plataforma. O trabalho com os autores envolve: listar, padronizar, comparar com os dados existentes na plataforma e levantar os dados necessários para novos cadastros. Resultados: Este novo desafio assumido pela biblioteca, que antes já fornecia os dados ao Serviço de Pós-Graduação, fez com que a equipe ampliasse a preocupação durante o processamento da produção científica, para facilitar a inclusão dos dados na plataforma, bem como garantir a sua confiabilidade para a avaliação do Programa de Pós-Graduação do instituto. Conclusão: Concluímos que os serviços prestados pelas bibliotecas universitárias devem ser repensados, fornecendo o apoio necessário para manutenção ou elevação dos índices de avaliação dos programas de suas Unidades.
Mapeamento de processos no contexto dos produtos químicos controlados
Authors:   Universidade Estadual de Campinas, Bergo Patricia Luisa de Souza , Yoshinaga Fabiana ,   Universidade Estadual de Campinas, Venturini Anderson de Oliveira ,   Universidade Estadual de Campinas
Published: February 2024

Introdução: O mapeamento de processos é uma ferramenta consolidada de planejamento e gestão que permite conhecer todos os fluxos de trabalho da unidade, suas características e limitações. Objetivo: O presente trabalho visou mapear os processos de trabalho do Escritório de Produtos Controlados (EPC/DEPI) da Unicamp consolidados. Metodologia: Inicialmente, levantaram-se todas as informações relacionadas às sequências de atividades de cada um dos processos de trabalho da unidade. Os dados foram compilados e organizados em mapas de processos, construídos utilizando a plataforma colaborativa digital Miro®. Após a revisão final, cada processo foi validado por um funcionário externo ao EPC. Resultados: Foram mapeados os processos de renovação dos Alvarás de Funcionamento e do Certificado de Vistoria, bem como do protocolo dos mapas de controle da Polícia Civil - SP. Também foram mapeados os processos de obtenção do Certificado de Registro do Exército Brasileiro e de renovação do Certificado de Licença de Funcionamento da Polícia Federal. Os processos foram analisados, identificando-se os pontos críticos que demandam melhorias. Algumas etapas foram suprimidas e outras incluídas, de forma a tornar o serviço mais eficiente. Conclusão: Os processos de trabalho do EPC já consolidados, foram mapeados com sucesso. Essa ferramenta de planejamento possibilitou otimizar o fluxo de atividades, melhorando a eficiência do trabalho desenvolvido pela unidade.
A falando com as mãos! : a Libras e o código braille nas vivências do Prodecad
Authors:   Universidade Estadual de Campinas, Stamponi Marcela Aparecida da
Published: February 2024

Introdução: O projeto ocorre na Turma da Criatividade (17 crianças entre 6 e 11 anos) no espaço de educação não formal no Programa de Desenvolvimento da Criança e do Adolescente (Prodecad) da Divisão de Educação Infantil e Complementar (DEdIC) ligado à Diretoria Executiva de Ensino Pré-Universitário (DEEPU) da Universidade Estadual de Campinas (UNICAMP). Objetivo: Proporcionar para esse grupo de crianças aspectos que tangem a acessibilidade da pessoa surda ou cega. Metodologia: As atividades ocorrem diariamente na rotina das crianças durante a permanência no Prodecad. São apresentados para as crianças alguns sinais da Língua de Sinais Brasileira (Libras) e código braille (decodificação tátil do alfabeto). Resultados: As rodas de conversa permitem às crianças a elaboração de aprendizados à sua maneira, assim como prevê a pedagogia da escuta, proposta como fundamento do trabalho na educação não formal. O projeto expandiu-se para diversos setores da Universidade. Pessoas que a dialogaram com as crianças e sobre a cultura surda e visuais e as adaptações sociais necessárias para as pessoas com deficiências auditivas e visuais. Conclusão: Certamente, o projeto é relevante porque apresenta às crianças sobre inclusão e acessibilidade. Esse trabalho pode ser uma inspiração para que outras instituições de educação tracem planos em prol de uma educação inclusiva. O “Falando com as Mãos!” é um exemplo, sem custo financeiro, de que o diálogo é um dos fundamentos para uma proposta de inclusão da diferença.
Fluxo de Alta da Unidade de Internação de Adultos para Otimização de Liberação de Leitos no Hospital de Clínicas da UNICAMP
Authors:   Universidade Estadual de Campinas, Julio Paulo Rogerio , Recco Elenita Ap de Castro ,   Universidade Estadual de Campinas, Graciano Joaquim Antonio ,   Universidade Estadual de Campinas, TanaKa Suelma Sarchi ,   Universidade Estadual de Campinas, Zapparoli Luciana Alves ,   Universidade Estadual de Campinas, Gardin Ligiane Maciel Rezende ,   Universidade Estadual de Campinas, Bordin Ana Paula ,   Universidade Estadual de Campinas
Published: February 2024

Introdução: O leito hospitalar é considerado um recurso escasso, sendo necessário um bom aproveitamento deste, com o uso adequado e no tempo oportuno, garantindo que o paciente acesse-o o mais breve possível e a gestão de leitos é realizada com a finalidade de manter a eficiência hospitalar e garantir o maior giro de leito, disponibilizando e atendendo a demanda de pacientes. Objetivo: Liberação dos leitos hospitalares imediatamente após a saída do paciente. Agilizar o processo de internação eletiva ou de urgência. Otimizar o giro de leitos Metodologia: Relato de experiência sobre o gerenciamento de leitos no Hospital de Clínicas/UNICAMP, redirecionando os pacientes em alta para o NIR, sendo neste local realizada a liberação do leito no sistema informatizado AGHUse, e disponibilizado nova internação em até 2 horas. Resultados: O estudo avaliou o tempo de liberação em 14 meses antes da implantação do projeto e 18 meses após a implantação do mesmo, onde encontramos uma redução nos tempos para liberação dos leitos após a alta médica efetivada no sistema informatizado. Com isso conseguimos melhorar a liberação dos leitos e efetivar maior número de internações em até 02 horas tanto eletiva quanto de urgência. A cada hora que reduzimos a permanência do paciente com alta no hospital, conseguimos aumentar a internação em até 2,83 pacientes/dia, totalizando 85 novas internações/mês e melhorando nosso giro de leito. Conclusão: Conseguimos demonstrar nos resultados melhora no giro de leito e nas internações para os pacientes da nossa comunidade, atingindo todos os nossos objetivos propostos.