bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure S4 from Macrophage Infiltration and Alternative Activation during Wound Healing Promote MEK1-Induced Skin Carcinogenesis
Authors: Weber Christine , Telerman Stephanie B. , Reimer Andreas S. , Sequeira Ines , Liakath-Ali Kifayathullah , Arwert Esther N. , Watt Fiona M.
Published: March 2023

Frozen wound sections collected 1, 6 and 13 days after wounding
Supplementary Figure S2 from Macrophage Infiltration and Alternative Activation during Wound Healing Promote MEK1-Induced Skin Carcinogenesis
Authors: Weber Christine , Telerman Stephanie B. , Reimer Andreas S. , Sequeira Ines , Liakath-Ali Kifayathullah , Arwert Esther N. , Watt Fiona M.
Published: March 2023

Manual quantification of CD11b+F4/80+ and F4/80+ cells in the dermis of InvEE and WT skin during different wound healing time points and in unwounded skin
Supplementary Figure S4 from Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis
Authors: Guo Yabin , Updegraff Barrett L. , Park Sunho , Durakoglugil Deniz , Cruz Victoria H. , Maddux Sarah , Hwang Tae Hyun , O'Donnell Kathryn A.
Published: March 2023

Consensus clustering analysis of the top 163 CIS genes in acute lymphocytic leukemia.
Supplementary Figure Legend from Macrophage Infiltration and Alternative Activation during Wound Healing Promote MEK1-Induced Skin Carcinogenesis
Authors: Weber Christine , Telerman Stephanie B. , Reimer Andreas S. , Sequeira Ines , Liakath-Ali Kifayathullah , Arwert Esther N. , Watt Fiona M.
Published: March 2023

Legend for Supplementary Figures S1-S6.
Supplementary Table 2 from Cancer Stem-like Cells Act via Distinct Signaling Pathways in Promoting Late Stages of Malignant Progression
Authors: da Silva-Diz Victoria , Simón-Extremera Pilar , Bernat-Peguera Adrià , de Sostoa Jana , Urpí Maria , Penín Rosa M. , Sidelnikova Diana Pérez , Bermejo Oriol , Viñals Joan Maria , Rodolosse Annie , González-Suárez Eva , Moruno Antonio Gómez , Pujana Miguel Ángel , Esteller Manel , Villanueva Alberto , Viñals Francesc , Muñoz Purificación
Published: March 2023

Table S2. List of differentially expressed genes between E-CSCs and L-CSCs, which were isolated from WD-SCCs and PD/S-SCCs, respectively.
Supplementary Figures 1 through 7, Supplementary Tables 1 and 3, and Supplementary Materials and Methods from Cancer Stem-like Cells Act via Distinct Signaling Pathways in Promoting Late Stages of Malignant Progression
Authors: da Silva-Diz Victoria , Simón-Extremera Pilar , Bernat-Peguera Adrià , de Sostoa Jana , Urpí Maria , Penín Rosa M. , Sidelnikova Diana Pérez , Bermejo Oriol , Viñals Joan Maria , Rodolosse Annie , González-Suárez Eva , Moruno Antonio Gómez , Pujana Miguel Ángel , Esteller Manel , Villanueva Alberto , Viñals Francesc , Muñoz Purificación
Published: March 2023

Figure S1. Generation and characterization of orthotopic SCC lineages. Figure S2. Analysis of CSC frequency and EMT induction during SCC progression. Figure S3. Characterization of primary culture cells derived of WD-SCCs and PD/S-SCCs. Figure S4. Activation of autocrine PDGFRα signaling in PD/S-SCCs. Figure S5. In vitro and in vivo assays showing that the inhibition of PDGFRα signaling does not affect the frequency of CSCs, EMT or PD/S-SCC growth. Figure S6. Activation of autocrine FGFR1 signaling in PD/S cells. Figure S7. L-CSC signature identifies advanced and poor-prognosis human lung and head-neck SCCs. Table S1. Histopathological features of distinct primary and orthotopically-derived SCCs (SCC lineages) at different passages. Table S3. List of human skin SCCs samples used in this study. Histopathological features of these samples are described. Supplementary Materials and Methods.
Supplementary Figure S12 from Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis
Authors: Guo Yabin , Updegraff Barrett L. , Park Sunho , Durakoglugil Deniz , Cruz Victoria H. , Maddux Sarah , Hwang Tae Hyun , O'Donnell Kathryn A.
Published: March 2023

Analysis of myeloid and lymphoid lineage markers in tumors.
Supplementary Table S5 from MSH2 Dysregulation Is Triggered by Proinflammatory Cytokine Stimulation and Is Associated with Liver Cancer Development
Authors: Eso Yuji , Takai Atsushi , Matsumoto Tomonori , Inuzuka Tadashi , Horie Takahiro , Ono Koh , Uemoto Shinji , Lee Kyeryoung , Edelmann Winfried , Chiba Tsutomu , Marusawa Hiroyuki
Published: March 2023

The signaling pathways and biological processes of the mutated genes in 6 HCC tissues
Supplementary Figure 9 from Antagonizing Integrin β3 Increases Immunosuppression in Cancer
Authors: Su Xinming , Esser Alison K. , Amend Sarah R. , Xiang Jingyu , Xu Yalin , Ross Michael H. , Fox Gregory C. , Kobayashi Takayuki , Steri Veronica , Roomp Kirsten , Fontana Francesca , Hurchla Michelle A. , Knolhoff Brett L. , Meyer Melissa A. , Morgan Elizabeth A. , Tomasson Julia C. , Novack Joshua S. , Zou Wei , Faccio Roberta , Novack Deborah V. , Robinson Stephen D. , Teitelbaum Steven L. , DeNardo David G. , Schneider Jochen G. , Weilbaecher Katherine N.
Published: March 2023

Integrin beta3 antagonist treatment on tumor cells and BMMs in culture
Supplementary Table S2 from MSH2 Dysregulation Is Triggered by Proinflammatory Cytokine Stimulation and Is Associated with Liver Cancer Development
Authors: Eso Yuji , Takai Atsushi , Matsumoto Tomonori , Inuzuka Tadashi , Horie Takahiro , Ono Koh , Uemoto Shinji , Lee Kyeryoung , Edelmann Winfried , Chiba Tsutomu , Marusawa Hiroyuki
Published: March 2023

Summary of whole-exome sequencing
Supplementary Figure 6 from Antagonizing Integrin β3 Increases Immunosuppression in Cancer
Authors: Su Xinming , Esser Alison K. , Amend Sarah R. , Xiang Jingyu , Xu Yalin , Ross Michael H. , Fox Gregory C. , Kobayashi Takayuki , Steri Veronica , Roomp Kirsten , Fontana Francesca , Hurchla Michelle A. , Knolhoff Brett L. , Meyer Melissa A. , Morgan Elizabeth A. , Tomasson Julia C. , Novack Joshua S. , Zou Wei , Faccio Roberta , Novack Deborah V. , Robinson Stephen D. , Teitelbaum Steven L. , DeNardo David G. , Schneider Jochen G. , Weilbaecher Katherine N.
Published: March 2023

Integrin gene expression of WT and Itgb3-/- BMMs after M1 or M2 polarization
CTL CD103+ on rICAM-Fc from TGFβ Signaling Intersects with CD103 Integrin Signaling to Promote T-Lymphocyte Accumulation and Antitumor Activity in the Lung Tumor Microenvironment
Authors: Boutet Marie , Gauthier Ludiane , Leclerc Marine , Gros Gwendoline , de Montpreville Vincent , Théret Nathalie , Donnadieu Emmanuel , Mami-Chouaib Fathia
Published: March 2023

CTL CD103+ on rICAM-Fc from TGFβ Signaling Intersects with CD103 Integrin Signaling to Promote T-Lymphocyte Accumulation and Antitumor Activity in the Lung Tumor Microenvironment
Supplementary Figure 4 from Myeloid-Derived Suppressor Cells Endow Stem-like Qualities to Breast Cancer Cells through IL6/STAT3 and NO/NOTCH Cross-talk Signaling
Authors: Peng Dongjun , Tanikawa Takashi , Li Wei , Zhao Lili , Vatan Linda , Szeliga Wojciech , Wan Shanshan , Wei Shuang , Wang Yin , Liu Yan , Staroslawska Elzbieta , Szubstarski Franciszek , Rolinski Jacek , Grywalska Ewelina , Stanisławek Andrzej , Polkowski Wojciech , Kurylcio Andrzej , Kleer Celina , Chang Alfred E. , Wicha Max , Sabel Michael , Zou Weiping , Kryczek Ilona
Published: March 2023

MDSCs produce NO and IL-6 and induce tumor STAT3 phosphorylation
Supplementary Table 1 from An Anti-EGFR IgA That Displays Improved Pharmacokinetics and Myeloid Effector Cell Engagement In Vivo
Authors: Lohse Stefan , Meyer Saskia , Meulenbroek Laura A.P.M. , Jansen J.H. Marco , Nederend Maaike , Kretschmer Anna , Klausz Katja , Möginger Uwe , Derer Stefanie , Rösner Thies , Kellner Christian , Schewe Denis , Sondermann Peter , Tiwari Sanjay , Kolarich Daniel , Peipp Matthias , Leusen Jeanette H.W. , Valerius Thomas
Published: March 2023

Iontrap aquisition Settings according to MIRAGE Guidelines.
Supplementary Figures from Agonists of the TRAIL Death Receptor DR5 Sensitize Intestinal Stem Cells to Chemotherapy-Induced Cell Death and Trigger Gastrointestinal Toxicity
Authors: Finnberg Niklas K. , Gokare Prashanth , Navaraj Arunasalam , Lang Kuhs Krystle A. , Cerniglia George , Yagita Hideo , Takeda Kazuyoshi , Motoyama Noboru , El-Deiry Wafik S.
Published: March 2023

Supplementary Figures 1-9. Sup. Fig. 1: IV injections of the monoclonal DR5-targeting MD5-1 antibody in combination with fluorouracil (5-FU) and CPT-11 sensitizes mice to chemotherapy-induced toxicity. Area-under-the curve (AUC) analysis of weight loss curves following different doses of fluorouracil (5-FU). Sup. Fig. 2: High dose treatment with the DR5-targeting antibody MD5-1 in combination with low-dose CPT-11 triggers liver toxicity whereas low dose MD5-1-treatment combined with high dose chemo triggers GI-toxicity in mouse strains known to be resistant to TRAIL-R-targeting. Sup. Fig. 3: Targeting of DR5 in combination with radiochemotherapy does not trigger synergistic bone marrow toxicity. Sup. Fig. 4: DR5-targeting sensitizes human small intestinal epithelial cells to cell death following chemotherapy. Sup. Fig. 5: DR5-targeting in combination with chemotherapy triggers cell death in the crypts of the GI tract in mice in vivo. Sup. Fig. 6: P53-dependent gene expression changes in the mouse colonic epithelium following fluorouracil and irinotecan. Affymetrix gene expression mRNA data on p53-responsive genes in the colon of mice treated with 5-FU (A) and CPT-11 (B). Sup. Fig. 7: Chemotherapy-dependent reliance on cell cycle regulating- and apoptosis-signaling genes for the toxic response following chemotherapy and DR5-targeting. Sup. Fig. 8: Chk2 is a modulator GIT following combined chemotherapy and DR5-targeting. Sup. Fig. 9: Pharmacologic targeting of Chk2 countermeasure GIT without impacting the anti-tumor response following chemotherapy and DR5-targeting.
Supplementary Figures 1 through 11 and Supplementary Figure and Video Legends from Modeling Spontaneous Metastasis following Surgery: An In Vivo-In Silico Approach
Authors: Benzekry Sebastien , Tracz Amanda , Mastri Michalis , Corbelli Ryan , Barbolosi Dominique , Ebos John M.L.
Published: March 2023

Supplementary Figure 1. In vitro fit and direct statistical analysis of the xenograft breast data. Supplementary Figure 2. Population fit of the tumor growth data. Supplementary Figure 3. Population fits of the breast xenograft data under different growth theories. Supplementary Figure 4. Population fits of the kidney isograft data under different growth theories. Supplementary Figure 5. Second kidney data set used for fitting the data (resection time = 23 days). Supplementary Figure 6. Individual fits of primary tumor and metastatic burden kinetics. Supplementary Figure 7. Individual fits of primary tumor and metastatic burden kinetics. Supplementary Figure 8. Link between experimental and model survival. Supplementary Figure 9: Surgery benefit on survival and metastatic burden reduction as a function of resection size, for varying values of metastatic potential. Supplementary Figure 10. Population fits of the ortho-surgical metastasis animal models. Supplementary Figure 11. Population fits of the ortho-surgical metastasis animal models.
Supplementary Movie 2 from Metabolic Stress-Induced Phosphorylation of KAP1 Ser473 Blocks Mitochondrial Fusion in Breast Cancer Cells
Authors: Cheng Chun-Ting , Kuo Ching-Ying , Ouyang Ching , Li Chien-Feng , Chung Yiyin , Chan David C. , Kung Hsing-Jien , Ann David K.
Published: March 2023

Movie 2. Time-lapse imaging of MDA-MB-231 cells in glucose-depleted medium.
Supplementary Table S6 from HBXIP and LSD1 Scaffolded by lncRNA Hotair Mediate Transcriptional Activation by c-Myc
Authors: Li Yinghui , Wang Zhen , Shi Hui , Li Hang , Li Leilei , Fang Runping , Cai Xiaoli , Liu Bowen , Zhang Xiaodong , Ye Lihong
Published: March 2023

Enrichment for c-Myc targets which could not be occupied by HBXIP.
Supplementary Figure S4 from HBXIP and LSD1 Scaffolded by lncRNA Hotair Mediate Transcriptional Activation by c-Myc
Authors: Li Yinghui , Wang Zhen , Shi Hui , Li Hang , Li Leilei , Fang Runping , Cai Xiaoli , Liu Bowen , Zhang Xiaodong , Ye Lihong
Published: March 2023

The expression levels of LSD1 mRNA are positively associated with those of HBXIP and c-Myc mRNAs in breast cancer tissues.
Supplementary_siNRP2 autophagy from Neuropilin-2 Regulates Endosome Maturation and EGFR Trafficking to Support Cancer Cell Pathobiology
Authors: Dutta Samikshan , Roy Sohini , Polavaram Navatha S. , Stanton Marissa J. , Zhang Heyu , Bhola Tanvi , Hönscheid Pia , Donohue Terrence M. , Band Hamid , Batra Surinder K. , Muders Michael H. , Datta Kaustubh
Published: March 2023

Autophagy_live cell
Supplementary Fig 5 from Neuropilin-2 Regulates Endosome Maturation and EGFR Trafficking to Support Cancer Cell Pathobiology
Authors: Dutta Samikshan , Roy Sohini , Polavaram Navatha S. , Stanton Marissa J. , Zhang Heyu , Bhola Tanvi , Hönscheid Pia , Donohue Terrence M. , Band Hamid , Batra Surinder K. , Muders Michael H. , Datta Kaustubh
Published: March 2023

Analysis of late endosomal protein PIKfyve
Supplementary Figure S5 from Rapalogs Efficacy Relies on the Modulation of Antitumor T-cell Immunity
Authors: Beziaud Laurent , Mansi Laura , Ravel Patrice , Marie-Joseph Elodie Lauret , Laheurte Caroline , Rangan Laurie , Bonnefoy Francis , Pallandre Jean-René , Boullerot Laura , Gamonet Clémentine , Vrecko Sindy , Queiroz Lise , Maurina Tristan , Mouillet Guillaume , Hon Thierry Nguyen Tan , Curtit Elsa , Royer Bernard , Gaugler Béatrice , Bayry Jagadeesh , Tartour Eric , Thiery-Vuillemin Antoine , Pivot Xavier , Borg Christophe , Godet Yann , Adotévi Olivier
Published: March 2023

This file contains contains CD8 responses in immune groups: Supplementary figure 5
Supplementary Figure S8 from Upregulation of Cytosolic Phosphoenolpyruvate Carboxykinase Is a Critical Metabolic Event in Melanoma Cells That Repopulate Tumors
Authors: Li Yong , Luo Shunqun , Ma Ruihua , Liu Jing , Xu Pingwei , Zhang Huafeng , Tang Ke , Ma Jingwei , Zhang Yi , Liang Xiaoyu , Sun Yanling , Ji Tiantian , Wang Ning , Huang Bo
Published: March 2023

Supplementary Figure S8. A schematic was drawn to show metabolic pathway in melanoma TRCs.
Supplementary Figure S4 from Rapalogs Efficacy Relies on the Modulation of Antitumor T-cell Immunity
Authors: Beziaud Laurent , Mansi Laura , Ravel Patrice , Marie-Joseph Elodie Lauret , Laheurte Caroline , Rangan Laurie , Bonnefoy Francis , Pallandre Jean-René , Boullerot Laura , Gamonet Clémentine , Vrecko Sindy , Queiroz Lise , Maurina Tristan , Mouillet Guillaume , Hon Thierry Nguyen Tan , Curtit Elsa , Royer Bernard , Gaugler Béatrice , Bayry Jagadeesh , Tartour Eric , Thiery-Vuillemin Antoine , Pivot Xavier , Borg Christophe , Godet Yann , Adotévi Olivier
Published: March 2023

This file contains the two groups statistic model: Supplementary figure 4
Supplementary Figure S7 from Upregulation of Cytosolic Phosphoenolpyruvate Carboxykinase Is a Critical Metabolic Event in Melanoma Cells That Repopulate Tumors
Authors: Li Yong , Luo Shunqun , Ma Ruihua , Liu Jing , Xu Pingwei , Zhang Huafeng , Tang Ke , Ma Jingwei , Zhang Yi , Liang Xiaoyu , Sun Yanling , Ji Tiantian , Wang Ning , Huang Bo
Published: March 2023

Supplementary Figure S7. High methylation in promoter region of PCK1 gene. B16 TRCs and control cells were used for DNA isolation.
Supplementary Figure S2 from Rapalogs Efficacy Relies on the Modulation of Antitumor T-cell Immunity
Authors: Beziaud Laurent , Mansi Laura , Ravel Patrice , Marie-Joseph Elodie Lauret , Laheurte Caroline , Rangan Laurie , Bonnefoy Francis , Pallandre Jean-René , Boullerot Laura , Gamonet Clémentine , Vrecko Sindy , Queiroz Lise , Maurina Tristan , Mouillet Guillaume , Hon Thierry Nguyen Tan , Curtit Elsa , Royer Bernard , Gaugler Béatrice , Bayry Jagadeesh , Tartour Eric , Thiery-Vuillemin Antoine , Pivot Xavier , Borg Christophe , Godet Yann , Adotévi Olivier
Published: March 2023

This file contains the lymphocytes count in patients: Supplementary figure 2
Supplementary Figure S5 from Upregulation of Cytosolic Phosphoenolpyruvate Carboxykinase Is a Critical Metabolic Event in Melanoma Cells That Repopulate Tumors
Authors: Li Yong , Luo Shunqun , Ma Ruihua , Liu Jing , Xu Pingwei , Zhang Huafeng , Tang Ke , Ma Jingwei , Zhang Yi , Liang Xiaoyu , Sun Yanling , Ji Tiantian , Wang Ning , Huang Bo
Published: March 2023

Supplementary Figure S5. Inhibition of PCK1 enzymatic activity repressed TRC growth and PCK1 knockdown didn't affect B16 TRC apoptosis.
Supplementary Table S3 from Decreased Expression of Fructose-1,6-bisphosphatase Associates with Glucose Metabolism and Tumor Progression in Hepatocellular Carcinoma
Authors: Hirata Hidenari , Sugimachi Keishi , Komatsu Hisateru , Ueda Masami , Masuda Takaaki , Uchi Ryutaro , Sakimura Shotaro , Nambara Sho , Saito Tomoko , Shinden Yoshiaki , Iguchi Tomohiro , Eguchi Hidetoshi , Ito Shuhei , Terashima Kotaro , Sakamoto Katsumi , Hirakawa Masakazu , Honda Hiroshi , Mimori Koshi
Published: March 2023

Overall survival based on the expression levels of genes specific to gluconeogenesis and aerobic glycolysis.
Supplementary Table S1 from Decreased Expression of Fructose-1,6-bisphosphatase Associates with Glucose Metabolism and Tumor Progression in Hepatocellular Carcinoma
Authors: Hirata Hidenari , Sugimachi Keishi , Komatsu Hisateru , Ueda Masami , Masuda Takaaki , Uchi Ryutaro , Sakimura Shotaro , Nambara Sho , Saito Tomoko , Shinden Yoshiaki , Iguchi Tomohiro , Eguchi Hidetoshi , Ito Shuhei , Terashima Kotaro , Sakamoto Katsumi , Hirakawa Masakazu , Honda Hiroshi , Mimori Koshi
Published: March 2023

Copy number and expression profiles of FBP1 in liver cancer cell lines from the Cancer Cell Line Encyclopedia.
Supplementary Figure S4 from Decreased Expression of Fructose-1,6-bisphosphatase Associates with Glucose Metabolism and Tumor Progression in Hepatocellular Carcinoma
Authors: Hirata Hidenari , Sugimachi Keishi , Komatsu Hisateru , Ueda Masami , Masuda Takaaki , Uchi Ryutaro , Sakimura Shotaro , Nambara Sho , Saito Tomoko , Shinden Yoshiaki , Iguchi Tomohiro , Eguchi Hidetoshi , Ito Shuhei , Terashima Kotaro , Sakamoto Katsumi , Hirakawa Masakazu , Honda Hiroshi , Mimori Koshi
Published: March 2023

The activity of gluconeogenesis and aerobic glycolysis predicted survival in patients with HCC.
Supplementary Tables 1-7 from Establishment and Characterization of an In Vitro Model of Ovarian Cancer Stem-like Cells with an Enhanced Proliferative Capacity
Authors: Ishiguro Tatsuya , Sato Ai , Ohata Hirokazu , Ikarashi Yoshinori , Takahashi Ryou-u , Ochiya Takahiro , Yoshida Masayuki , Tsuda Hitoshi , Onda Takashi , Kato Tomoyasu , Kasamatsu Takahiro , Enomoto Takayuki , Tanaka Kenichi , Nakagama Hitoshi , Okamoto Koji
Published: March 2023

Supplementary Table S1. Information on clinical data of SOCs and sphere formation. Supplementary Table S2. Xenograft tumor formation assay of the ovarian spheroids (#4). Supplementary Table S3. Limited dilution assay on the FACS-sorted spheroid cells. Supplementary Table S4. Clinicopathological features of high-grade serous ovarian carcinoma patients. Supplementary Table S5. Statistical analyses of ALDH1A1 expression in advanced-stage high-grade serous ovarian carcinoma. Supplementary Table S6. Limited dilution assays for the sh-ALDH1A1-infected cells. Supplementary Table S7. Limited dilution assays for the sh-SOX2-infected cells.
Table S2 from Non–Small Cell Lung Cancer Cells Acquire Resistance to the ALK Inhibitor Alectinib by Activating Alternative Receptor Tyrosine Kinases
Authors: Isozaki Hideko , Ichihara Eiki , Takigawa Nagio , Ohashi Kadoaki , Ochi Nobuaki , Yasugi Masayuki , Ninomiya Takashi , Yamane Hiromichi , Hotta Katsuyuki , Sakai Katsuya , Matsumoto Kunio , Hosokawa Shinobu , Bessho Akihiro , Sendo Toshiaki , Tanimoto Mitsune , Kiura Katsuyuki
Published: March 2023

Probe and primer
Suppl. Figure 8 from Non–Small Cell Lung Cancer Cells Acquire Resistance to the ALK Inhibitor Alectinib by Activating Alternative Receptor Tyrosine Kinases
Authors: Isozaki Hideko , Ichihara Eiki , Takigawa Nagio , Ohashi Kadoaki , Ochi Nobuaki , Yasugi Masayuki , Ninomiya Takashi , Yamane Hiromichi , Hotta Katsuyuki , Sakai Katsuya , Matsumoto Kunio , Hosokawa Shinobu , Bessho Akihiro , Sendo Toshiaki , Tanimoto Mitsune , Kiura Katsuyuki
Published: March 2023

Long-term effects of crizotinib on tumor growth in xenograft models
Suppl. Figure 5 from Non–Small Cell Lung Cancer Cells Acquire Resistance to the ALK Inhibitor Alectinib by Activating Alternative Receptor Tyrosine Kinases
Authors: Isozaki Hideko , Ichihara Eiki , Takigawa Nagio , Ohashi Kadoaki , Ochi Nobuaki , Yasugi Masayuki , Ninomiya Takashi , Yamane Hiromichi , Hotta Katsuyuki , Sakai Katsuya , Matsumoto Kunio , Hosokawa Shinobu , Bessho Akihiro , Sendo Toshiaki , Tanimoto Mitsune , Kiura Katsuyuki
Published: March 2023

ALK kinase domain sequencing
Supplementary Table and Figure Legends from Hypoxia-Induced Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma Induces an Immunosuppressive Tumor Microenvironment to Promote Metastasis
Authors: Ye Long-Yun , Chen Wei , Bai Xue-Li , Xu Xing-Yuan , Zhang Qi , Xia Xue-Feng , Sun Xu , Li Guo-Gang , Hu Qi-Da , Fu Qi-Han , Liang Ting-Bo
Published: March 2023

Legends for Supplementary Tables S1-S2 and Supplementary Figures S1-S6.
Supplemental Figure Legend from Decoding Intratumoral Heterogeneity of Breast Cancer by Multiparametric In Vivo Imaging: A Translational Study
Authors: Schmitz Jennifer , Schwab Julian , Schwenck Johannes , Chen Qian , Quintanilla-Martinez Leticia , Hahn Markus , Wietek Beate , Schwenzer Nina , Staebler Annette , Kohlhofer Ursula , Aina Olulanu H. , Hubbard Neil E. , Reischl Gerald , Borowsky Alexander D. , Brucker Sara , Nikolaou Konstantin , la Fougère Christian , Cardiff Robert D. , Pichler Bernd J. , Schmid Andreas M.
Published: March 2023

Detailed description of mean and max value analysis of ADC and [18F]FDG data of tumors of tg(PyV-mT) mice.
Supplementary Figures 1-10 from Cdx2 Expression and Intestinal Metaplasia Induced by H. pylori Infection of Gastric Cells Is Regulated by NOD1-Mediated Innate Immune Responses
Authors: Asano Naoki , Imatani Akira , Watanabe Tomohiro , Fushiya Jun , Kondo Yutaka , Jin Xiaoyi , Ara Nobuyuki , Uno Kaname , Iijima Katsunori , Koike Tomoyuki , Strober Warren , Shimosegawa Tooru
Published: March 2023

Supplementary Figure 1. Cdx2 expression in human gastric epithelial cell lines. Supplementary Figure 2. The expression of Cdx2 was enhanced by H. pylori infection in gastric epithelial cell. Supplementary Figure 3. Scheme of the Cdx2 prmoter-luciferase reporter plasmids used in this study. Supplementary Figure 4. BAY11-7082 inhibits NF-κB activation. Supplementary Figure 5. NOD1 siRNA reduced the expression of NOD1. Supplementary Figure 6. Cdx2 and MUC2 expression in GSM06 cells. Supplementary Figure 7. Pretreatment with iE-DAP reduces H. pylori infection-induced Cdx2 expression. Supplementary Figure 8. iE-DAP alone does not alter Cdx2 expression. Supplementary Figure 9. Inflammatory scores of the stomach did not differ between NOD1-intact and NOD1-deficient mice. Supplementary Figure 10. TNF-α was induced in the stomachs of H. pylori-infected mice.
Supplementary Figure S3 from Hypoxia-Induced Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma Induces an Immunosuppressive Tumor Microenvironment to Promote Metastasis
Authors: Ye Long-Yun , Chen Wei , Bai Xue-Li , Xu Xing-Yuan , Zhang Qi , Xia Xue-Feng , Sun Xu , Li Guo-Gang , Hu Qi-Da , Fu Qi-Han , Liang Ting-Bo
Published: March 2023

Monocytes co-cultured with hepatoma cells exhibit a higher level of expression of CD206 and CD163, indicating differentiation into suppressive MMs.
Supplementary Tables and Figures from AKT1 Inhibits Epithelial-to-Mesenchymal Transition in Breast Cancer through Phosphorylation-Dependent Twist1 Degradation
Authors: Li Chia-Wei , Xia Weiya , Lim Seung-Oe , Hsu Jennifer L. , Huo Longfei , Wu Yun , Li Long-Yuan , Lai Chien-Chen , Chang Shih-Shin , Hsu Yi-Hsin , Sun Hui-Lung , Kim Jongchan , Yamaguchi Hirohito , Lee Dung-Fang , Wang Hongmei , Wang Yan , Chou Chao-Kai , Hsu Jung-Mao , Lai Yun-Ju , LaBaff Adam M. , Ding Qingqing , Ko How-Wen , Tsai Fuu-Jen , Tsai Chang-Hai , Hortobagyi Gabriel N. , Hung Mien-Chie
Published: March 2023

Supplementary Table S1. Relationship between expression of AKT1, β-TrCP, Twist1, and E-cadherin in surgical specimens of breast cancer. Supplementary Table S2. Antibodies used in Western blotting and immunoprecipitation. Supplementary Figure S1. AKT1 is downregulated in aggressive breast cancer. Supplementary Figure S2. AKT1 preferentially interacts with Twist1. Supplementary Figure S3. AKT1 phosphorylates Twist1 at two putative motifs. Supplementary Figure S4. AKT1 induces β-TrCP mediated Twist1 degradation. Supplementary Figure S5. Twist1 AVA induces a stronger EMT phenotypic change. Supplementary Figure S6. Twist1 AVA induces a stronger EMT phenotypic change. Supplementary Figure S7. Clinical association of AKT1, β-TrCP, Twist1 and E-caherin expression in breast cancer patients. Supplementary Figure S8. MK-2206 induces EMT phenotypic change. Supplementary Figure S8. Clinical association of AKT1, β-TrCP, Twist1 and E-caherin expression in breast cancer patients. Supplementary Figure S9. MK-2206 induces EMT phenotypic change.
legends of supplemental figures from RASSF1A Suppresses the Invasion and Metastatic Potential of Human Non–Small Cell Lung Cancer Cells by Inhibiting YAP Activation through the GEF-H1/RhoB Pathway
Authors: Dubois Fatéméh , Keller Maureen , Calvayrac Olivier , Soncin Fabrice , Hoa Lily , Hergovich Alexander , Parrini Maria-Carla , Mazières Julien , Vaisse-Lesteven Mélissa , Camonis Jacques , Levallet Guénaëlle , Zalcman Gérard
Published: March 2023

legends of all supplemental figures
Table S2 from RASSF1A Suppresses the Invasion and Metastatic Potential of Human Non–Small Cell Lung Cancer Cells by Inhibiting YAP Activation through the GEF-H1/RhoB Pathway
Authors: Dubois Fatéméh , Keller Maureen , Calvayrac Olivier , Soncin Fabrice , Hoa Lily , Hergovich Alexander , Parrini Maria-Carla , Mazières Julien , Vaisse-Lesteven Mélissa , Camonis Jacques , Levallet Guénaëlle , Zalcman Gérard
Published: March 2023

Plasmids used in this study.
HBEC-3 2D-migration induced by RASS1A-knockdown from RASSF1A Suppresses the Invasion and Metastatic Potential of Human Non–Small Cell Lung Cancer Cells by Inhibiting YAP Activation through the GEF-H1/RhoB Pathway
Authors: Dubois Fatéméh , Keller Maureen , Calvayrac Olivier , Soncin Fabrice , Hoa Lily , Hergovich Alexander , Parrini Maria-Carla , Mazières Julien , Vaisse-Lesteven Mélissa , Camonis Jacques , Levallet Guénaëlle , Zalcman Gérard
Published: March 2023

HBEC-3 2D-migration induced by RASS1A-knockdown showed features evoking both collective migration and multicellular streaming
Supplementary Table 2 from Phosphotyrosine Signaling Analysis in Human Tumors Is Confounded by Systemic Ischemia-Driven Artifacts and Intra-Specimen Heterogeneity
Authors: Gajadhar Aaron S. , Johnson Hannah , Slebos Robbert J.C. , Shaddox Kent , Wiles Kerry , Washington Mary Kay , Herline Alan J. , Levine Douglas A. , Liebler Daniel C. , White Forest M.
Published: March 2023

Supplementary Table 2. Basal state of ovarian tumor samples
Figure S4: trans-endothelial invasion, enhanced-migration and growth in soft agar upon RASSF1A depletion in 4 transformed and untransformed epithelial bronchial cell lines. from RASSF1A Suppresses the Invasion and Metastatic Potential of Human Non–Small Cell Lung Cancer Cells by Inhibiting YAP Activation through the GEF-H1/RhoB Pathway
Authors: Dubois Fatéméh , Keller Maureen , Calvayrac Olivier , Soncin Fabrice , Hoa Lily , Hergovich Alexander , Parrini Maria-Carla , Mazières Julien , Vaisse-Lesteven Mélissa , Camonis Jacques , Levallet Guénaëlle , Zalcman Gérard
Published: March 2023

The cells were transiently transfected with siNeg, siRASSF1A or siRASSF1AC. The experiences were performed 48 hours after transfection A. The trans-endothelial invasion capacity of transfected cells was assessed using a cell culture insert (BioCoat Matrigel Invasion Chamber) on which a monolayer of endothelial cells has been grown previously. The total number of cells that invaded to the lower side of the filter after 48h was counted under the microscope (10X). The relative invasion was normalized to that of the cells transfected with siNeg. B. The migration speed (µm/h) of transfected HBEC-3 RasV12, H1975 and BEAS-2B cells was determined by wound healing assay on Fibronectin (HBEC-3) or collagen IV (H1975 and BEAS-2B). Mitomycin C (1 µg/ml) was added to medium 12h before wounding. C. The invasion capacity of transfected HBEC-3RasV12, H1975, BEAS-2B, BEAS-2B RasV12 cells was assessed using BioCoat Matrigel Invasion Chambers. The total number of cells that invaded to the lower side of the filter after 48h was counted under the microscope (10X). The relative invasion was normalized to that of the cells transfected with siNeg. D. The capacity of growth without adherence in soft agar of HBEC-3 RasV12 and BEAS-2B cells transfected by an inactive siRNA or SiRASSF1A was evaluated by quantification of colony formation. The number of colonies was scored after 7 days. One representative experiment is shown in a right panel. Scale bar represents 80 µm. For all of the histograms, error bars indicate the standard error of the mean (SEM) of at least three independent experiments. For all of the histograms, error bars indicate the standard error of the mean (SEM) of at least three independent experiments. *p<0.05, **p<0.01 and ***p<0.001, using an ANOVA test followed by Dunnett's test.
Supplemental Figure Legends from Autocrine Secretion of Progastrin Promotes the Survival and Self-Renewal of Colon Cancer Stem–like Cells
Authors: Giraud Julie , Failla Laura M. , Pascussi Jean-Marc , Lagerqvist Ebba L. , Ollier Jérémy , Finetti Pascal , Bertucci François , Ya Chu , Gasmi Imène , Bourgaux Jean-François , Prudhomme Michel , Mazard Thibault , Ait-Arsa Imade , Houhou Leila , Birnbaum Daniel , Pélegrin André , Vincent Charles , Ryall James G. , Joubert Dominique , Pannequin Julie , Hollande Frédéric
Published: March 2023

Legend for Supplemental Figures S1-S6.
Supplemental Figure Legends from M-COPA, a Golgi Disruptor, Inhibits Cell Surface Expression of MET Protein and Exhibits Antitumor Activity against MET-Addicted Gastric Cancers
Authors: Ohashi Yoshimi , Okamura Mutsumi , Hirosawa Asaka , Tamaki Naomi , Akatsuka Akinobu , Wu Kuo-Ming , Choi Hyeong-Wook , Yoshimatsu Kentaro , Shiina Isamu , Yamori Takao , Dan Shingo
Published: March 2023

Supplemental Figure Legends
Supplementary Figure Legends from IL6 Trans-signaling Promotes KRAS-Driven Lung Carcinogenesis
Authors: Brooks Gavin D. , McLeod Louise , Alhayyani Sultan , Miller Alistair , Russell Prudence A. , Ferlin Walter , Rose-John Stefan , Ruwanpura Saleela , Jenkins Brendan J.
Published: March 2023

Legends for supplementary figures.
Supplementary Materials and Methods from Ivermectin Induces Cytostatic Autophagy by Blocking the PAK1/Akt Axis in Breast Cancer
Authors: Dou Qianhui , Chen Hai-Ning , Wang Kui , Yuan Kefei , Lei Yunlong , Li Kai , Lan Jiang , Chen Yan , Huang Zhao , Xie Na , Zhang Lu , Xiang Rong , Nice Edouard C. , Wei Yuquan , Huang Canhua
Published: March 2023

Supplementary Materials and Methods
Supplemental Figures from Aberrant Activation of Notch Signaling Inhibits PROX1 Activity to Enhance the Malignant Behavior of Thyroid Cancer Cells
Authors: Choi Dongwon , Ramu Swapnika , Park Eunkyung , Jung Eunson , Yang Sara , Jung Wonhyeuk , Choi Inho , Lee Sunju , Kim Kyu Eui , Seong Young Jin , Hong Mingu , Daghlian George , Kim Daniel , Shin Eugene , Seo Jung In , Khatchadourian Vicken , Zou Mengchen , Li Wei , De Filippo Roger , Kokorowski Paul , Chang Andy , Kim Steve , Bertoni Ana , Furlanetto Tania Weber , Shin Sung , Li Meng , Chen Yibu , Wong Alex , Koh Chester , Geliebter Jan , Hong Young-Kwon
Published: March 2023

Supplemental Figures. Fig S1:Expression of HEY1 and HEY2 in thyroid cancers vs. normal thyroid tissues. Fig S2:PROX1 mislocalization in TPC-1 cells does not depend on CRM1, energy or temperature. Fig S3: T3 promotes PROX1 nuclear exclusion in a dose-dependent manner. Fig S4: Engineered BCPAP cells conditionally express FLAG-tagged PROX1 by doxycycline administration. Fig S5: Wnt/β-catenin signaling is suppressed in PTC cells. Fig S6: PROX1-mediated regulation of thyroid cancer-associated genes in TPC1 and 8505c cells. Fig S7: Single cell motility assay. Fig S8: Reinstatement of PROX1 expression in TPC1 and 8505c thyroid cancer cells. Fig S9: Dox-induced expression of PROX1 in BCPAP tumor cells in mouse. Fig S10: PROX1 re-expression inhibits tumor growth and aggressive tumor cell morphology of TPC1 thyroid carcinoma cells. Fig S11: PROX1 re-expression suppressed tumor growth and aggressive morphology of 8505c thyroid cancer cells. Fig S12: Cytoplasmic localization of PROX1 in other cancer cells.
Supplemental Figure S3 from Identification of Bone-Derived Factors Conferring De Novo Therapeutic Resistance in Metastatic Prostate Cancer
Authors: Lee Yu-Chen , Lin Song-Chang , Yu Guoyu , Cheng Chien-Jui , Liu Bin , Liu Hsuan-Chen , Hawke David H. , Parikh Nila U. , Varkaris Andreas , Corn Paul , Logothetis Christopher , Satcher Robert L. , Yu-Lee Li-Yuan , Gallick Gary E. , Lin Sue-Hwa
Published: March 2023

Effects of integrin ligands on C4-2B4 soft agar colony formation.
Supplementary Figures 1-8, Supplementary Tables 1-3 from Identification of DNA Methylation–Independent Epigenetic Events Underlying Clear Cell Renal Cell Carcinoma
Authors: Becket Elinne , Chopra Sameer , Duymich Christopher E. , Lin Justin J. , You Jueng Soo , Pandiyan Kurinji , Nichols Peter W. , Siegmund Kimberly D. , Charlet Jessica , Weisenberger Daniel J. , Jones Peter A. , Liang Gangning
Published: March 2023

Supplementary Figure 1. Quantitation and location of epigenetic changes in all 6 patient samples. Supplementary Figure 2. Significant accessibility changes between 6 patients. Supplementary Figure 3. Accessibility changes shared in at least two patient samples, plotted in heatmaps, either losing accessibility (Groups a and e) or gaining accessibility (Groups d and f) with or without DNA methylation. Supplementary Figure 4. ChIP-seq analyses of Patient 5. Supplementary Figure 5. Validation of AcceSssIble data from each Group a, d, e, and f using locus-specific bisulfite sequencing. Supplementary Figure 6. Correlation plots of chromatin accessibility and DNA methylation changes vs. gene expression changes. Supplementary Figure 7. Epigenetically-regulated genes in the HIF1A-signaling pathway and VHL status in each ccRCC patient. Supplementary Figure 8. Example diagram of M.SssI treatment efficacy. Supplementary Table 1. List of loci with methylation-dependent accessibility changes that positively correlate with expression changes from TCGA RNA-seq data. Supplementary Table 2. List of loci with methylation-independent accessibility changes that positively correlate with expression changes from TCGA RNA-seq data. Supplementary Table 3. List of genes overlapping between epigenetically-regulated genes from our study, and commonly mutated genes in ccRCC from TCGA.
Supplementary figure S3 from JX06 Selectively Inhibits Pyruvate Dehydrogenase Kinase PDK1 by a Covalent Cysteine Modification
Authors: Sun Wenyi , Xie Zuoquan , Liu Yifu , Zhao Dan , Wu Zhixiang , Zhang Dadong , Lv Hao , Tang Shuai , Jin Nan , Jiang Hualiang , Tan Minjia , Ding Jian , Luo Cheng , Li Jian , Huang Min , Geng Meiyu
Published: March 2023

PDK inhibition by JX06 in different cancer cells.
Movie 3 from Mesenchymal Stem Cell–Derived Exosomes Stimulate Cycling Quiescence and Early Breast Cancer Dormancy in Bone Marrow
Authors: Bliss Sarah A. , Sinha Garima , Sandiford Oleta A. , Williams Lisa M. , Engelberth Daniel J. , Guiro Khadidiatou , Isenalumhe Leidy L. , Greco Steven J. , Ayer Seda , Bryan Margarette , Kumar Rakesh , Ponzio Nicholas M. , Rameshwar Pranela
Published: March 2023

CD63-GFP (green) transfected cells Donor Cells/ Lower well
Supplementary Materials and Methods from ICOS Promotes the Function of CD4+ Effector T Cells during Anti-OX40–Mediated Tumor Rejection
Authors: Metzger Todd C. , Long Hua , Potluri Shobha , Pertel Thomas , Bailey-Bucktrout Samantha L. , Lin John C. , Fu Tihui , Sharma Padmanee , Allison James P. , Feldman Reid M.R.
Published: March 2023

Supplementary Materials and Methods
Supplementary Figure S4 from ICOS Promotes the Function of CD4+ Effector T Cells during Anti-OX40–Mediated Tumor Rejection
Authors: Metzger Todd C. , Long Hua , Potluri Shobha , Pertel Thomas , Bailey-Bucktrout Samantha L. , Lin John C. , Fu Tihui , Sharma Padmanee , Allison James P. , Feldman Reid M.R.
Published: March 2023

ICOS blockade does not impair CD8+ T cell-driven anti-tumor immunity
Supplementary Figure S3 from ICOS Promotes the Function of CD4+ Effector T Cells during Anti-OX40–Mediated Tumor Rejection
Authors: Metzger Todd C. , Long Hua , Potluri Shobha , Pertel Thomas , Bailey-Bucktrout Samantha L. , Lin John C. , Fu Tihui , Sharma Padmanee , Allison James P. , Feldman Reid M.R.
Published: March 2023

Gating strategy to identify ICOS+ and ICOS- T cells
Supplementary Figure 10 from miR-155 Drives Metabolic Reprogramming of ER+ Breast Cancer Cells Following Long-Term Estrogen Deprivation and Predicts Clinical Response to Aromatase Inhibitors
Authors: Bacci Marina , Giannoni Elisa , Fearns Antony , Ribas Ricardo , Gao Qiong , Taddei Maria Letizia , Pintus Gianfranco , Dowsett Mitch , Isacke Clare M. , Martin Lesley-Ann , Chiarugi Paola , Morandi Andrea
Published: March 2023

Supplementary Figure S10. Tamoxifen-treated patients expressing high levels of HK2, GLUT1, MCT4 and miR155 show worst prognosis.
Supplementary Figure S1 from ICOS Promotes the Function of CD4+ Effector T Cells during Anti-OX40–Mediated Tumor Rejection
Authors: Metzger Todd C. , Long Hua , Potluri Shobha , Pertel Thomas , Bailey-Bucktrout Samantha L. , Lin John C. , Fu Tihui , Sharma Padmanee , Allison James P. , Feldman Reid M.R.
Published: March 2023

OX86-mG2a specifically depletes tumor Tregs
Supplemental Materials and Methods from Cancer-Associated Fibroblasts in Pancreatic Cancer Are Reprogrammed by Tumor-Induced Alterations in Genomic DNA Methylation
Authors: Xiao Qian , Zhou Donger , Rucki Agnieszka A. , Williams Jamila , Zhou Jiaojiao , Mo Guanglan , Murphy Adrian , Fujiwara Kenji , Kleponis Jennifer , Salman Bulent , Wolfgang Christopher L. , Anders Robert A. , Zheng Shu , Jaffee Elizabeth M. , Zheng Lei
Published: March 2023

Instrument settings for MethySYBR PCR Pryosequencing primers and targeted sequence Instrument settings for immunofluorescence Instrument settings for SOCS1 Immunohistochemistry
Supplementary Table S1 from Hybrid Manganese Dioxide Nanoparticles Potentiate Radiation Therapy by Modulating Tumor Hypoxia
Authors: Abbasi Azhar Z. , Gordijo Claudia R. , Amini Mohammad Ali , Maeda Azusa , Rauth Andrew M. , DaCosta Ralph S. , Wu Xiao Yu
Published: March 2023

Summary of reported rates of H2O2 production by different cancer cell lines and estimated H2O2 production in a solid tumor of ~100 mm3 in volume.
Supplemental Figures and Tables from Cancer-Associated Fibroblasts in Pancreatic Cancer Are Reprogrammed by Tumor-Induced Alterations in Genomic DNA Methylation
Authors: Xiao Qian , Zhou Donger , Rucki Agnieszka A. , Williams Jamila , Zhou Jiaojiao , Mo Guanglan , Murphy Adrian , Fujiwara Kenji , Kleponis Jennifer , Salman Bulent , Wolfgang Christopher L. , Anders Robert A. , Zheng Shu , Jaffee Elizabeth M. , Zheng Lei
Published: March 2023

Table S1. Primer sequences Table S2. Promoter methylation status of 8 genes in 3 paired primary PDAC cells and CAFs measured by methylation specific PCR Table S3. SOCS1 methylation analyzed by pryosequencing in stroma dissected from PDAC tissues Table S4 Pyrosequencing results of five methylation sites on the SOCS1 promoter in MSCs or CAFs* before or after co-culture with human PDAC cells. Table S5. A list of clusters with a minimum of 5 genes that are both methylated and downregulated in CAFs upon interacting with PDAC tumor cells Table S6. Summary of genes with expression alterations (fold of change >1.5) in MSC cocultured with Panc10.05T vs. singly cultured MSC in both methylated genes (beta value > 0.5) and unmethylated genes (beta value < 0.5), respectively Figure S1. Representative pyrosequencing results. Figure S2. DNMT1 mRNA expression in MSC cells following shRNA knockdown of DNMT1. Figure S3. Pathways most significantly upregulated in CAFs upon co-culturing with PDAC tumor cells. Figure S4. SOCS1 expression in MSC cells following shRNA knockdown of SOCS1.
Supplemental Table 3 from Genomic Profiling of Pediatric Acute Myeloid Leukemia Reveals a Changing Mutational Landscape from Disease Diagnosis to Relapse
Authors: Farrar Jason E. , Schuback Heather L. , Ries Rhonda E. , Wai Daniel , Hampton Oliver A. , Trevino Lisa R. , Alonzo Todd A. , Guidry Auvil Jaime M. , Davidsen Tanja M. , Gesuwan Patee , Hermida Leandro , Muzny Donna M. , Dewal Ninad , Rustagi Navin , Lewis Lora R. , Gamis Alan S. , Wheeler David A. , Smith Malcolm A. , Gerhard Daniela S. , Meshinchi Soheil
Published: March 2023

List of all segment variations
Supplemental Table 1 from Genomic Profiling of Pediatric Acute Myeloid Leukemia Reveals a Changing Mutational Landscape from Disease Diagnosis to Relapse
Authors: Farrar Jason E. , Schuback Heather L. , Ries Rhonda E. , Wai Daniel , Hampton Oliver A. , Trevino Lisa R. , Alonzo Todd A. , Guidry Auvil Jaime M. , Davidsen Tanja M. , Gesuwan Patee , Hermida Leandro , Muzny Donna M. , Dewal Ninad , Rustagi Navin , Lewis Lora R. , Gamis Alan S. , Wheeler David A. , Smith Malcolm A. , Gerhard Daniela S. , Meshinchi Soheil
Published: March 2023

Patient Characteristics
Supplemental Figure 2 from Genomic Profiling of Pediatric Acute Myeloid Leukemia Reveals a Changing Mutational Landscape from Disease Diagnosis to Relapse
Authors: Farrar Jason E. , Schuback Heather L. , Ries Rhonda E. , Wai Daniel , Hampton Oliver A. , Trevino Lisa R. , Alonzo Todd A. , Guidry Auvil Jaime M. , Davidsen Tanja M. , Gesuwan Patee , Hermida Leandro , Muzny Donna M. , Dewal Ninad , Rustagi Navin , Lewis Lora R. , Gamis Alan S. , Wheeler David A. , Smith Malcolm A. , Gerhard Daniela S. , Meshinchi Soheil
Published: March 2023

Gene expression (array based) of recurrently mutated genes. Graph shows normalized expression of each patient and normal bone marrow (BM) controls for 9 of the 10 recurrently mutated genes; DHX30 was not represented on the array.
Supplementary movie 2 from FIH Is an Oxygen Sensor in Ovarian Cancer for G9a/GLP-Driven Epigenetic Regulation of Metastasis-Related Genes
Authors: Kang Jengmin , Shin Seung-Hyun , Yoon Haejin , Huh June , Shin Hyun-Woo , Chun Yang-Sook , Park Jong-Wan
Published: March 2023

Molecular dynamics simulation of H3K9me2 binding to N867-hydroxylated GLP-ARD. These movies are related to main Fig. 3D.
Figures 1-2 from FIH Is an Oxygen Sensor in Ovarian Cancer for G9a/GLP-Driven Epigenetic Regulation of Metastasis-Related Genes
Authors: Kang Jengmin , Shin Seung-Hyun , Yoon Haejin , Huh June , Shin Hyun-Woo , Chun Yang-Sook , Park Jong-Wan
Published: March 2023

Histone H3/4 modifications and oxygen-dependent H3K9 methylation by FIH and G9a/GLP. This file is related to Fig. 1.
Figure S9-11 from FIH Is an Oxygen Sensor in Ovarian Cancer for G9a/GLP-Driven Epigenetic Regulation of Metastasis-Related Genes
Authors: Kang Jengmin , Shin Seung-Hyun , Yoon Haejin , Huh June , Shin Hyun-Woo , Chun Yang-Sook , Park Jong-Wan
Published: March 2023

FIH-G9a axis controls the growth and metastasis of OvCa xenografts. This file is related to Fig. 5.
Supplementary table 1 from Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer
Authors: Hu Nan , Kadota Mitsutaka , Liu Huaitian , Abnet Christian C. , Su Hua , Wu Hailong , Freedman Neal D. , Yang Howard H. , Wang Chaoyu , Yan Chunhua , Wang Lemin , Gere Sheryl , Hutchinson Amy , Song Guohong , Wang Yuan , Ding Ti , Qiao You-Lin , Koshiol Jill , Dawsey Sanford M. , Giffen Carol , Goldstein Alisa M. , Taylor Philip R. , Lee Maxwell P.
Published: March 2023

Summary of demographic and clinical data for 15 sequenced cancer cases.
Figure S4 from Synergistic Activation of ERα by Estrogen and Prolactin in Breast Cancer Cells Requires Tyrosyl Phosphorylation of PAK1
Authors: Oladimeji Peter , Skerl Rebekah , Rusch Courtney , Diakonova Maria
Published: March 2023

This file contains Supplemental Figure S4 entitled "Selective inhibitors inhibit multiple pathways".
Supplementary Figure 2 from Phytoestrogen Suppresses Efflux of the Diagnostic Marker Protoporphyrin IX in Lung Carcinoma
Authors: Fujita Hirofumi , Nagakawa Keisuke , Kobuchi Hirotsugu , Ogino Tetsuya , Kondo Yoichi , Inoue Keiji , Shuin Taro , Utsumi Toshihiko , Utsumi Kozo , Sasaki Junzo , Ohuchi Hideyo
Published: March 2023

ALA-induced PpIX accumulation in tumor and normal dermal tissue.
Supplemetary Figure S2 from BPTF Depletion Enhances T-cell–Mediated Antitumor Immunity
Authors: Mayes Kimberly , Alkhatib Suehyb G. , Peterson Kristen , Alhazmi Aiman , Song Carolyn , Chan Vivian , Blevins Tana , Roberts Mark , Dumur Catherine I. , Wang Xiang-Yang , Landry Joseph W.
Published: March 2023

BPTF depleted 4T1 tumors are flat compared to controls and BPTF does not affect MDSC amplification or metastasis to the lung.
Supplemental Figures from Frequency and Dynamics of Leukemia-Initiating Cells during Short-term Ex Vivo Culture Informs Outcomes in Acute Myeloid Leukemia Patients
Authors: Griessinger Emmanuel , Anjos-Afonso Fernando , Vargaftig Jacques , Taussig David C. , Lassailly François , Prebet Thomas , Imbert Véronique , Nebout Marielle , Vey Norbert , Chabannon Christian , Filby Andrew , Bollet-Quivogne Frederic , Gribben John G. , Peyron Jean-François , Bonnet Dominique
Published: March 2023

Supplemental Figures
Supplementary Figure Legends from SOX9 Elevation Acts with Canonical WNT Signaling to Drive Gastric Cancer Progression
Authors: Santos Juliana Carvalho , Carrasco-Garcia Estefania , Garcia-Puga Mikel , Aldaz Paula , Montes Milagrosa , Fernandez-Reyes Maria , de Oliveira Caroline Candida , Lawrie Charles H , Araúzo-Bravo Marcos J. , Ribeiro Marcelo Lima , Matheu Ander
Published: March 2023

Legends of supplementary figures
Table S1 and S2 from Restraining Network Response to Targeted Cancer Therapies Improves Efficacy and Reduces Cellular Resistance
Authors: Das Tirtha K. , Esernio Jessica , Cagan Ross L.
Published: March 2023

Shows statistics for drug screen in flies and CI index in human cell lines
Supplementary Tables S1-S7 from Nrf2 Activation Promotes Keratinocyte Survival during Early Skin Carcinogenesis via Metabolic Alterations
Authors: Rolfs Frank , Huber Marcel , Kuehne Andreas , Kramer Stefan , Haertel Eric , Muzumdar Sukalp , Wagner Johanna , Tanner Yasmine , Böhm Friederike , Smola Sigrun , Zamboni Nicola , Levesque Mitchell P. , Dummer Reinhard , Beer Hans-Dietmar , Hohl Daniel , Werner Sabine , Schäfer Matthias
Published: March 2023

List of genes associated with detoxification with a fold change of 1.5 or higher and p-value lower than 0.05 analyzed by microarray analysis using skin of P2.5 K5cre-caNrf2 compared to control mice (S1); Relative expression of genes encoding glycolysis enzymes determined by microarray analysis using skin of P2.5 K5cre-caNrf2 and control mice (S2); Expression levels of NQO1, SRXN1, G6PDX, PGD, TKT, IDH1 and ME1 relative to GAPDH as determined by qRT-PCR using RNA isolated from skin cancer precursor lesions and skin of healthy patients (S3); Murine qRT-PCR primers (S4); Human qRT-PCR primers (S5); Antibodies used for immunofluorescence or immunohistochemistry staining (S6); Antibodies used for western blotting (S7).