bluuebunny/crossref_metadata_2025 huggingface dataset:
Nghiên cứu tăng cường độ chính xác của cảm biến quang học sử dụng ánh sáng cận hồng ngoại định hướng ứng dụng y sinh
Authors: Nguyễn Tấn Tài
Published: June 2023

Nghiên cứu trình bày kết quả mô phỏng các đặc tính của cảm biến quang học sử dụng lăng kính dựa trên hiệu ứng cộng hưởng plasmon bề mặt với lớp phủ kim loại Ag và bước sóng ánh sáng 1064 nm. Kết quả nghiên cứu cho thấy cảm biến sử dụng lớp Ag với độ dày 60 nm sẽ cho độ chính xác của phép đo cao hơn 14 lần và độ xuyên sâu (789,6 nm) cao hơn 3,5 lần so với cảm biến sử dụng ánh sáng 633 nm. Độ nhạy của cảm biến này có kết quả đạt được là 93,40/RIU,  khá cao cho cảm biến sử dụng một lớp kim loại và thấp hơn 1,5 lần so với cảm biến sử dụng bước sóng 633 nm. Việc tăng cường độ chính xác và độ xuyên sâu của cảm biến sử dụng bước sóng 1064 nm đã mở ra tiềm năng ứng dụng lớn của cảm biến này trong lĩnh vực chẩn đoán sớm, dùng để đo các thực thể có kích thước lớn như vi khuẩn (1-20 µm) trong lĩnh vực y sinh.
Nhân giống in vitro lan kim tuyến (Anoectochilus sp.)
Authors: Nguyễn Trần Phước Huy , Đỗ Thị Mai Trinh
Published: June 2023

Lan kim tuyến (Anoectochilus sp.) thuộc họ Orchidaceae là một trong những loại dược liệu quý của Việt Nam. Dịch chiết chứa các hợp chất liên quan đến chức năng tim mạch như các arachidonic acid, β – sitosterol… Mục đích của nghiên cứu là thiết lập một quy trình nhân giống in vitro để bảo tồn và phát triển loài lan kim tuyến bằng cách sử dụng các chất điều hoà sinh trưởng (6-benzylaminopurine, thidiazudron) kết hợp với kỹ thuật cắt lát mỏng tế bào. Kết quả cho thấy môi trường Murashige & Skoog bổ sung 0,5 mg/L 6-benzylaminopurine kết hợp 0,5 mg/L thidiazuron là tối ưu cho sự phát sinh chồi lan kim tuyến với 3,67 chồi/mẫu. Kỹ thuật cắt lát mỏng tế bào theo chiều ngang kết hợp chiếu sáng ở 2.000 lux cho số lượng chồi phát sinh từ lát cắt cao nhất với 13,16 chồi/mẫu. Các chồi in vitro lan kim tuyến ra rễ tối ưu trên môi trường Murashige & Skoog giảm 25% cả đa lượng và vi lượng. Các kết quả này có thể sử dụng để nhân giống quy mô lớn cây lan kim tuyến.
So sánh năng suất và hiệu quả tài chính của hai mô hình nuôi thu trứng và sinh khối artemia ở độ mặn thấp
Authors: Nguyễn Văn Hòa , Trần Nguyễn Hải Nam , Nguyễn Tiến Dũng
Published: June 2023

Hai mô hình nuôi Artemia được tiến hành đồng thời trên các ao nuôi diện tích 2.000 m2 (2 ao cho mỗi mô hình). Mật độ thả lần lượt là 200 con/L đối với mô hình nuôi sinh khối và 100 con/L đối với mô hình thu trứng. Kết quả cho thấy về yếu tố môi trường nuôi tương tự nhau ở hai mô hình. Mật độ quần thể cao nhất ở mô hình sinh khối là 366 con/L và mô hình thu trứng là 237con/L. Năng suất, mô hình sinh khối thu được 3,04 tấn sinh khối và 14,6 kg trứng/ha/vụ; và mô hình thu trứng thì năng suất 71,5 kg trứng và 520,1 kg sinh khối/ha/vụ. Tổng chi phí cho mô hình nuôi sinh khối là 45,0±9,1 triệu đồng/ha/vụ và lợi nhuận trung bình thu được 74,5±21,5 triệu đồng/ha/vụ cao hơn 1,6 lần so với mô hình thu trứng (45,8± 25,0 triệu đồng/ha/vụ).
Diễn ngôn người trần thuật trong truyện ngắn Trần Bảo Định
Authors: Lê Thị Nhiên , Nguyễn Trung Nhân
Published: June 2023

Nghiên cứu văn học từ góc nhìn diễn ngôn có ý nghĩa thiết thực về mặt khoa học và thực tiễn. Các đặc điểm trong diễn ngôn người kể chuyện qua truyện ngắn của Trần Bảo Định được khái quát trong bài viết. Các thành phần tường thuật, miêu tả, bình luận trong diễn ngôn người kể chuyện được xác định và có sự phân tích, đánh giá thông qua các sáng tác cụ thể. Từ đó, có thể chỉ ra những nét riêng trong lối kể chuyện của nhà văn Trần Bảo Định.
Đánh giá mối tương quan giữa thực hành du lịch có trách nhiệm và hành vi dự định du lịch có trách nhiệm của khách du lịch
Authors: Nguyễn Thi Thanh Nga , Lê Thị Thanh Xuân , Phan Thị Thuỳ Linh , Đặng Thị Thuý Hiền
Published: June 2023

Du lịch có trách nhiệm (DLCTN) đã trở nên phổ biến và nhận được sự quan tâm của nhiều nhà nghiên cứu nhưng còn ít nghiên cứu tìm kiếm mối quan hệ giữa sự tham gia của khách du lịch (KDL) và hành vi có trách nhiệm. Nghiên cứu này xem xét mối quan hệ giữa thực hành DLCTN của KDL với hành vi dự định DLCTN. Thực hành DLCTN của KDL được đánh giá dựa trên ba khía cạnh: trách nhiệm kinh tế, trách nhiệm văn hóa xã hội và trách nhiệm môi trường. Số liệu nghiên cứu là 220 bảng hỏi từ KDL nội địa đến Thừa Thiên Huế, trong đó 200 bảng hỏi hợp lệ để phân tích. Phương pháp đo lường mô hình cấu trúc với SmartPLS được sử dụng để kiểm tra các giả thuyết. Kết quả nghiên cứu khẳng định các giả thuyết được chấp nhận, có mối quan hệ tích cực giữa thực hành DLCTN với hành vi dự định DLCTN. Trong đó, yếu tố trách nhiệm với môi trường đóng một vai trò quan trọng trong việc quyết định hành vi có trách nhiệm của KDL.
Sức khỏe tài chính của giới trẻ trên địa bàn Hà Nội: Vai trò của thảo luận tài chính, hiểu biết tài chính và ý thức tài chính
Authors: Nguyễn Vân Hà , Trương Hoàng Nam
Published: June 2023

Sức khỏe tài chính đóng vai trò nền tảng trong việc xây dựng và duy trì chất lượng cuộc sống về cả thể chất lẫn tinh thần. Việc nuôi dưỡng sức khỏe tài chính lành mạnh cho thế hệ trẻ lại càng trở nên đặc biệt quan trọng khi đây chính là nguồn lực chính cho sự phát triển của toàn xã hội. Mục tiêu của bài viết là đánh giá vai trò của thảo luận tài chính, hiểu biết tài chính và ý thức tài chính đối với sức khỏe tài chính của giới trẻ trên địa bàn Hà Nội. Dữ liệu nghiên cứu gồm 219 mẫu quan sát và mô hình hồi quy OLS. Kết quả nghiên cứu chỉ ra rằng thảo luận tài chính và ý thức tài chính ảnh hưởng tích cực và đáng kể tới sức khỏe tài chính của giới trẻ, trong khi tác động của hiểu biết tài chính là không đáng kể. Kết quả nghiên cứu gợi mở một số hàm ý quan trọng nhằm nâng cao hơn nữa sức khỏe tài chính cho giới trẻ.
Adsorption Isotherms for CBY 3G-P Dye Removal from Aqueous Media Using TiO2 Degussa, Fe2O3, and TiO2/(DPC)
Authors: Azeez Shireen Abdulmohsin , Hussein Fadhela Muhammad , Alsaedi Rasha Wali Mohi
Published: June 2023

The adsorption of Cibacron Brilliant Yellow (CBY) 3-GP dye onto TiO2 Degussa, Fe2O3, and TiO2 anatase/Diphenylcarbizide in aqueous solution was studied with respect to temperature, contact time, and pH. The CBY 3-GP adsorption at equilibrium increased as the initial dye concentration increased for TiO2/DPC, while it decreased for TiO2 Degussa; however, it increased the initial dye concentration. The best removal efficiency was obtained at 1 mg for TiO2/DPC, TiO2 Degussa, and the amount of adsorption decreases with the rising of temperature. The negative ΔH° reveals the adsorption is exothermic and extremely negative ΔS° for TiO2 Degussa. The negative value for ΔS° indicates a regular increase of the randomness at the TiO2/DPC and Fe2O3 solution interface during adsorption. The intraparticle diffusion, pseudo-first- and second-order kinetic models were used. The Langmuir, Temkin, Freundlich, and Dubbin adsorption models were examined to describe the equilibrium isotherms. The usage of TiO2 Degussa and TiO2/DPC indicates that the equilibrium sorption was favorable.
Investigation of Crystal Size Distribution in Purification of Terephthalic Acid from Polyester Textile Industry Waste by Reactive Crystallization
Authors: Marlena Bekti , Sulistyo Hary , Rochmadi Rochmadi
Published: June 2023

The purification of terephthalic acid recovered from an alkali-reduction wastewater by reactive crystallization was investigated. The crude terephthalic acid was reacted with sodium hydroxide solution to form a salt of disodium terephthalate, then acidified with sulfuric acid to get the terephthalic acid with higher purity. Effects of time, pH, concentration, and flow rate of secondary feed solutions, temperature, and stirring rate on Crystal Size Distribution (CSD) of terephthalic acid precipitate were investigated. The results showed that CSD was influenced by the concentration of reactants and the pH solution. On the other hand, time, temperature, flow rate of secondary solution, and stirring rate had no significant effects on the CSD, which the mean size of crystals ±3 μm. The mean size of crystals at solution pH 5, 4, and 3 were 6.03, 9.42, and 10.34 μm, respectively; meanwhile, at concentrations of 0.5, 0.3, and 0.1 M, were 7.57, 3.24, and 3.09 μm, respectively. The semi-batch reactive crystallization with double-feeding at constant pH and temperature produced monodispersed crystals. However, this method needs to be carried out more than once for terephthalic acid purification, which is intended for polyethylene terephthalate (PET) polymerization.
Pemanfaatan SFCL tipe Bridge untuk Meningkatkan Stabilitas Transien Microgrid dan Economic Feasibility
Authors: Roy Bayu Negara  , Fransisco Danang Wijaya  , Lesnanto Multa Putranto  , Mohd. Brado Frasetyo
Published: June 2023

Pembangkit energi terbarukan (renewable energy, RE) saat ini banyak digunakan oleh masyarakat sebagai upaya untuk mengurangi emisi. Untuk itu, dikembangkan sistem microgrid bersumber pada RE yang berdampingan dengan energi konvensional. Akan tetapi, sistem energi listrik tersebut cenderung mengalami gangguan transien seperti hubung singkat, beban bertambah, dan turunnya keluaran generator. Gangguan tersebut dapat menyebabkan turunnya tegangan dan tidak stabilnya frekuensi, sehingga diperlukan upaya untuk mempertahankan stabilitas sistem dengan menggunakan superconducting fault current limiter (SFCL). Pemilihan SFCL didasari oleh kemampuannya membatasi arus gangguan serta kecepatannya dalam memberikan perlindungan selama terjadinya gangguan transien. Model SFCL yang digunakan adalah SFCL tipe bridge dengan komponen utamanya adalah dua induktor. Pada model ini, dalam kondisi normal, arus mengalir melalui dua induktor. Ketika terjadi gangguan (fault), arus akan mengalir melalui satu induktor. Penelitian ini dilakukan dalam skenario terjadi gangguan. Pada saat kondisi terjadi gangguan, nilai tegangan tanpa SFCL tipe bridge adalah 2,5 V. Ketika SFCL tipe bridge digunakan, nilai tegangannya sebesar 207 V. Nilai arus terukur pada kondisi tanpa SFCL tipe bridge adalah 30 kA dan ketika menggunakan SFCL tipe bridge adalah 1,1 kA. Nilai frekuensi pada kondisi tanpa SFCL tipe bridge adalah 49,7 Hz hingga 50,2 Hz dan ketika menggunakan SFCL tipe bridge adalah 49,9 Hz sampai 50,1 Hz. Penelitian ini juga menambahkan perhitungan economic feasibility untuk mengetahui kelayakan sistem microgrid saat menggunakan SFCL tipe bridge. Perhitungannya terdiri atas empat bagian, yaitu net present value (NPV), profitability index (PI), discounted payback period (DPP), dan internal rate of return (IRR). Economic feasibility yang diperoleh yaitu nilai NPV sebesar US$6.865.405, nilai PI sebesar 2,4, nilai DPP selama empat tahun, dan nilai IRR sebesar 28,59%. Nilai yang diperoleh dibandingkan dengan standar kelayakan dan disimpulkan bahwa microgrid dengan adanya SFCL dapat dikatakan layak.
Bioprospecting and Exploration of the Natural Antifouling Approaches against Marine Foulers
Authors: Subbaiyan Rubavathi , Ganesan Ayyappadasan , Varadharajan Venkatraman
Published: June 2023

Biofouling is a significant problem in various industries, including marine, medical, and water treatment. It occurs when microorganisms, such as bacteria, fungi, and algae, attach to surfaces and form biofilms, which can lead to material degradation, decreased performance, and increased maintenance costs. Traditional approaches to mitigate biofouling include the use of biocides, physical cleaning, and chemical treatments. However, these methods have limitations, such as environmental concerns, short-term effectiveness, and development of resistant organisms. One alternative approach is the use of lichen-associated symbionts, which have been found to produce compounds that inhibit biofilm formation and growth. These compounds could be used to develop eco-friendly and sustainable antifouling coatings. Another promising approach is the use of nanotechnology to develop novel coatings that prevent biofouling. Nanomaterials can be engineered to have hydrophobic structures, which deter microorganisms from attaching to surfaces. They can also be designed to contain nano biocides, which can kill organisms that come into contact with the surfaces. Overall, the use of lichen-associated symbionts and nanotechnology holds great potential for developing effective and sustainable solutions to mitigate biofouling. However, further research is needed to optimize these approaches and ensure their safety and efficacy in various applications. This review offers a brief overview on the mechanisms of biofouling and evaluate the potential of using lichen-associated symbionts and nanotechnology to prevent or reduce biofouling.
The Electricity Generation Potential in Sugar Mill of Bhenda factory and Energy Conservation Activities
Authors: Dipak Patkal Akshada
Published: June 2023

Abstract: The cogeneration system is one of the most important parts of sugarcane mills which use the bagasse as fuel. In the recent years, modern equipment’s and energy efficiency measures made possible to the sugarcane industry, the production of surplus electricity which become, besides the sugar and ethanol, a third product from the same renewable source, the sugarcane. This work analyses the surplus electric power systems for three different schemes of cogeneration system in the sugarcane industry through the simulator thermoflow. The analysis is made considering both the available bagasse and sugarcane straw recovery as fuel in three different scenarios for the industrial process energy requirements
Future of Agro Industry with Advance Monitoring using Thingspeak
Authors: Patil Prof. Dr. C.S. , Sathe Miss. Shital P. , Patil Akshada A. , Mahajan Akanksha N. , Chavhan Sapana S.
Published: June 2023

bstract: In India, an important growing sector is agriculture. The major challenges in agriculture are crop productivity, soil nutrient level, smart irrigation system, crop monitoring, etc. This paper reviews the internet of things (IoT) based smart agriculture system using Thing Speak. The main purpose of this work is to improve the efficiency of the existing. Irrigation system and to reduce the human intervention for the complete automation of the system. The proposed system consists of raspberry pi, various sensors, and a motor driver. Raspberry pi is the main controlling unit that can control the operation of various sensors and actuators. The soil moisture sensor detects the moisture level in the soil and irrigates the crop in a controlled manner. If there is any variation in moisture level then the sensor will update the observed value and store in the cloud. In a smart monitoring system, will update the observed value and store in the cloud. In a smart monitoring system, transfers it to the cloud through raspberry pi. Here Pi is used to provide live video streaming. All this sensor data is stored in a Thing Speak cloud. So that we can view it from a remote location using Thing View Free mobile android application. All this sensor data we can also view on Thing Speak.
Amplitude Based Pilot Protection for Transmission Line
Authors: Wagh Amruta Narendra
Published: June 2023

Abstract: Distance protection and differential protection schemes are the two primary types of protection schemes employed in gearbox line protection today. However, industrial practice has shown that commonly used gap prevention techniques are limited in tripping speed and selectivity. The timing of the samples in each of the two relays located at the gearbox line terminals also affects the differential protection mechanism. On the other hand, pilot safety schemes using only the communication link to exchange local decision-making about fault conditions are not affected. These method include protection of Extra High Voltage (EHV) and Ultra High Voltage (UHV) transmission lines. Synchronization of time. The problem of creating a fast and accurate fault detection system for the safety of EHV/UHV transmission lines, which is crucial in present power systems, is the subject of this master's thesis. The protection method described in this thesis is the foundation for the detection and analysis of waves travelling wave along transmission at fault initiation. This method compares the arrival of the first traveling waves at both ends of the protected line with respect to direction. This will establish whether the fault is located in the safe zone or not. Based on high voltage transmission network safety requirements a suitable phase sequence algorithm is developed to control single phase tripping. Finally, through simulations conducted in the MATLAB environment, practical design concerns for incorporating the newly proposed protection algorithm into a numerical relay unit are investigated.
Is Overwork Culture a New Normal? Rethinking from Psychological Detachment Perspective.
Authors: Barik Smita , Yadav Dr. Jaya
Published: June 2023

Previous studies have shown and proven that employees need temporary detachment from their work to recharge and re-energize for the next day to work with similar enthusiasm. But work pressures and overwork culture have become a buzzword every corporate follows, and employees are bound to face it. This study investigates the impact of overwork culture (OWC) on employee longevity (EL). Further, it examines the mediating role of employee psychological detachment (EPD) on the linkage between OWC and EL. It aims to develop a relationship between psychological detachment and employee longevity, which can be referred to further to show how important the former's role is for the organization's welfare. The survey data was collected from 116 IT professionals from India, and the proposed relationship was analyzed through the SMART – PLS structural equation modeling tool. This study found a significant impact of Overwork Culture on EPD, but at the same time, the impact of OWC on EL is much less. This gives a scope to rethink the causes behind accepting this new norm. Also, our study fails to give the considerable impact of EPD on EL, and the mediating role of EPD can decrease up to 13% of the impact of OWC on EL. The originality of the research stems from the scarcity of research on EPD and almost no study on the mediating role of EPD on EL. This is one of the earliest studies to investigate the mediating role of EPD on EL with another independent variable. This proves the novelty of this study as it has a huge difference after Covid-era, where psychological detachment has less effect on employee longevity.
Case Reports Using Continuous Glucose Monitoring: Analysis For Application Of Digitalization In Management Of Diabetes Mellitus
Authors: Saxena Rajesh , B Singh Dr. Anurupa , .Singh Dr. N. P
Published: June 2023

Diabetes has emerged as a burgeoning health challenge in the last two decades. Specifically, there is an alarming rate of adult-onset diabetes mellitus, a point of deep concern. Therefore, cohesive steps are essential for the management of symptoms of diabetes mellitus to regulate its prevalence rate globally. Continuous glucose monitoring (CGM) technology can aid in this effort by allowing for safe therapy intensification with HbA1c (hemoglobin-a1c) reduction and by assisting in lowering some of the psychosocial impacts of diabetes. We aim to analyze the application of the digital device Freestyle Libre Pro in the management of diabetes mellitus. Using the FreeStyle Libre Pro CGM system, we analyzed the datasets for eight patients over 14 days. In addition, regular 12-hour data was monitored on a fortnight basis. Two of the eight cases were on insulin, and the rest were administered oral medications for diabetes care. Ambulatory Glucose Profiles, Average Glucose Levels, Time in Range, Time Below Range, Time Above Range, and, afterward, calculation of HbA1c levels were determined for eight patients using the FreeStyle Libre Pro system's current glucose measurements. We observed that for four patients, the average glucose levels were maintained in range, and for f our patients, the average glucose levels were above range. Regarding Time, four were above range, and four were in range. Our analysis shows that the Freestyle Libre Pro offers an alternative to current CGM devices for professional use as it may aid clinics and patients.
Analisis Trend Perkembangan Volume Impor Daging Sapi di Indonesia Selama Periode Tahun 2000–2020 dan Faktor-Faktor yang Mempemgaruhinya
Authors: Wulandari Dian Ikke , Fimansyah Fimansyah , Hoesni Fahroerrozi Hoesni
Published: June 2023

Tujuan dari penelitian ini untuk mengetahui trend perkembangan volume impor daging sapi di Indonesia selama periode tahun 2000-2020, untuk mengetahui pengaruh harga daging sapi impor,harga daging dalam negeri, konsumsi daging sapi, produksi daging sapi, dan nilai tukar rupiah di Indonesia selama periode tahun 2000-2020. Metode yang digunakan yaitu metode analisis data sekunder dengan data tahunan (time series). Hasil analisis pengaruh harga daging sapi impor dan harga daging sapi dalam negeri terhadap volume impor daging sapi menunjukkan bahwa adanya pengaruh yang signifikan (nyata), analisis pengaruh konsumsi daging sapi terhadap volume impor daging sapi menunjukkan bahwa tidak adanya pengaruh yang signifikan (nyata), analisis pengaruh produksi daging sapi terhadap volume impor daging sapi menunjukkan bahwa tidak adanya pengaruh yang signifikan (nyata), dan analisis pengaruh nilai tukar rupiah terhadap volume impor daging sapi menunjukkan bahwa tidak adanya pengaruh yang signifikan (nyata). Trend perkembangan volume impor daging sapi di Indonesia selama periode tahun 2000-2020 mengalami kecenderungan meningkat.
O ESTUDO DO MODELO COMBINATÓRIO DE PADOVAN POR MEIO DA ENGENHARIA DIDÁTICA
Authors: Passos Machado Vieira Renata , Vieira Alves Francisco Regis , Machado Cruz Catarino Paula Maria
Published: June 2023

A presente pesquisa retrata os dados mais relevantes de uma investigação fundamentada na metodologia de pesquisa da Engenharia Didática em conjunto com a metodologia de ensino da Teoria das Situações Didáticas. Visando abordar estratégias e teorias de ensino para o estudo de História da Matemática e sequências, tem-se uma interpretação combinatória da sequência de Padovan, guiada pela Engenharia Didática. Assim, é proposta e discutida uma questão, denominada de situação-problema, permitindo uma investigação em torno dos números de Padovan. As análises são realizadas com base nas metodologias citadas, visando oferecer novas abordagens de resoluções, para que os estudantes se tornem os protagonistas do seu próprio conhecimento. A investigação poderá ocorrer em cursos de formação inicial de professores de Matemática, promovendo uma visualização e vislumbre da sequência de Padovan diante de sua abordagem combinatória.  Por fim, conclui-se que a pesquisa fornece recursos para que ocorram repercussões e promoções de roteiros investigativos em cursos de formação inicial de professores de Matemática, no âmbito do ensino da sequência de Padovan.
DESEMPENHO FISCAL DOS MUNICÍPIOS: UMA ANÁLISE COMPARATIVA PARA AS MESORREGIÕES DO NORTE DE MINAS E TRIÂNGULO MINEIRO
Authors: Machado Lopes Roberto Paulo , Pereira Quaresma Marta
Published: June 2023

Este trabalho tem por objetivo analisar, em um estudo comparativo, o efeito da descentralização fiscal baseada em transferências no desempenho arrecadatório dos municípios das mesorregiões do Triangulo Mineiro e do Norte de Minas Gerais. Para isto procura relacionar os desníveis na arrecadação per capita entre os municípios (variável dependente) às transferências lump sum e à renda per capita. O estudo parte de duas hipóteses: (i) que as transferências intergovernamentais do tipo lump-sum, ao conceder uma fonte de receita incondicional e sem contrapartida, tende a reduzir o esforço fiscal dos governos municipais; (ii) que os municípios de regiões mais desenvolvidas e maior capacidade fiscal, apresentam um esforço de arrecadação maior que as regiões mais pobres. O estudo tem por base de análise o referencial teórico sobre descentralização fiscal baseado em transferências. Para testar as hipóteses estima-se modelo econométrico relacionando as variáveis e utiliza o método dos Mínimos Quadrados Ordinários (MQO). Os principais resultados apontam que as transferências lump sum reduzem o estímulo a arrecadação própria. No entanto, não se verificou diferenças significativas no esforço de arrecadação entre as mesorregiões analisadas.
HANNAH ARENDT: FILÓSOFA EM TEMPOS DE PERPLEXIDADE
Authors: Rodríguez Cruz Manuel , Amorim Lima Adenaide
Published: June 2023

Após um primeiro comentário sobre a recepção de Arendt na Espanha, o autor pretende usar as categorias centrais da obra A condição humana para abordar a questão da subjetividade humana em termos adequados ao tempo presente. Trata-se de levar em consideração todas aquelas determinações sem as quais não seria possível analisar hoje o problema da identidade: ação, fragilidade, natalidade, reconhecimento. Da mesma maneira, se pretende fugir de todos aqueles ideais de perfeição que no passado foram acolhidos sob o rótulo de utopia e que terminaram por revelar-se – como Arendt teve que sofrer em sua própria carne – como a causa primordial dos maiores horrores do nosso tempo.
SARTRE E AS IMPLICAÇÕES ÉTICAS DE SUA ONTOLOGIA
Authors: Da Silva Martins Jasson
Published: June 2023

Não discutiremos se existe ou não uma ética na obra de Sartre. Nosso objetivo é, partindo da sua ontologia, apresentar possíveis implicações éticas de sua filosofia. Todo o texto visa demonstrar que a afirmação irrestrita da liberdade humana conduz à luta pelo reconhecimento do Eu pelo Outro, como necessidade inevitável. O resultado deve revelar que não há liberdade sem reconhecimento de outra consciência livre.
O uso de jogos digitais no ensino de química: explorando o jogo Minecraft
Authors:   , Hazenfratz Bruno Ferreira
Published: June 2023

O presenta trabalho fala sobre o uso de jogos para o ensino dando exemplos de jogos variados como Minecraft que será usado como exemplo no resto do texto. Os objetivos gerais são demonstrar as ferramentas que o jogo Minecraft possui e que podem ser aplicadas no ensino da disciplina de química e os objetivos específicos são entender as ferramentas existentes no jogo Minecraft que são aplicáveis na educação, e demonstrar a aplicação das ferramentas do jogo Minecraft com aplicação no ensino da disciplina de química. Para a pesquisa foram usadas as plataformas Portal de anais UEMS (Universidade Estadual do Mato Grosso do Sul), Revista Valore (Revista Cientifica da FASF Faculdade Sul Fluminense), ResearchGate, Repositório Universitário da Ânima (RUNA), Repositório Digital Lume (UFRGS Universidade Federal do Rio Grande do Sul), Repositório Institucional UFSC (Universidade Federal de Santa Catarina) e Repositório UFAL (Universidade Federal de Alagoas) nos idiomas de português e inglês e priorizando pesquisas que tivessem a aplicação do jogo Minecraft em sala de aula. São usados exemplos de materiais que podem ser usados no ensino de química e são citados autores que aplicaram o Minecraft em sala de aula junto com gráficos para mostrar como os alunos lidaram com o jogo. É concluído que o jogo Minecraft pode ser usado para o ensino de química e pode ser aplicado em outras matérias dependendo de como o professor conseguir se acostumar com as ferramentas do jogo.
Human Papillomavirus Infection: Epidemiology, Biology, Host Interactions, Cancer Development, Prevention, and Therapeutics
Authors: Wolf Jonas Michel
Published: June 2023

Human papillomavirus (HPV) infection is one of the most common sexually
transmitted infections worldwide. It is caused by the human
papillomavirus, a DNA virus that infects epithelial cells in various
mucous membranes and skin surfaces. HPV can be categorized into
high-risk and low-risk types based on their association with the
development of certain cancers. High-risk HPV types, such as HPV-16 and
HPV-18, are known to be oncogenic and are strongly associated with the
development of cervical, anal, vaginal, vulvar, penile, and
oropharyngeal cancers. These types of HPV can persist in the body for an
extended period and, in some cases, lead to the formation of
precancerous lesions that may progress to cancer if left untreated.
Low-risk HPV types, such as HPV-6 and HPV-11, are not typically
associated with cancer but can cause benign conditions like genital
warts. Genital warts are characterized by the growth of small,
cauliflower-like bumps on the genital and anal areas. Although not
life-threatening, they can cause discomfort and psychological distress.
HPV is primarily transmitted through sexual contact, including vaginal,
anal, and oral sex. It can also be transmitted through non-penetrative
sexual activities that involve skin-to-skin contact. In addition to
sexual transmission, vertical transmission from mother to child during
childbirth is possible but relatively rare. Prevention of HPV infection
includes vaccination and safe sexual practices. HPV vaccines, such as
Gardasil and Cervarix, are highly effective in preventing infection with
the most common high-risk HPV types. These vaccines are typically
administered to adolescents and young adults before they become sexually
active. Safe sexual practices, such as consistent and correct condom use
and limiting the number of sexual partners, can also reduce the risk of
HPV transmission. Diagnosis of HPV infection can be challenging because
the infection is often asymptomatic, especially in men. In women, HPV
testing can be done through cervical screening programs, which involve
the collection of cervical cells for analysis. Abnormal results may lead
to further diagnostic procedures, such as colposcopy or biopsy, to
detect precancerous or cancerous changes. Overall, HPV infection is a
prevalent sexually transmitted infection with significant implications
for public health. Vaccination, regular screening, and early treatment
of precancerous lesions are key strategies to reduce the burden of
HPV-related diseases and their associated complications. Education and
awareness about HPV and its prevention are crucial in promoting optimal
sexual health. This study aimed to carry out a literature review
considering several aspects involving HPV infection: Global
distribution, prevalence, biology, host interactions, cancer
development, prevention, therapeutics, coinfection with other viruses,
coinfection with bacteria, association with head and neck squamous cell
carcinomas (HNSCC), and association with anal cancer.
Building a Predictive Model and Survival Analysis for Distant Metastases in Differentiated Thyroid Carcinoma: A Three Center Retrospective Study
Authors: Jiuping Huang , Yang Peipei , Zhendong Wang , Pei Feng , Huarong Li , Qian linxue
Published: June 2023

BACKGROUNDː Distant metastases (DM) occur rarely and are
associated with poor outcomes in patients with differentiated thyroid
carcinoma (DTC). The aim of this study was to explore potential risk
factors of DM in DTC and build a decision-tree model. METHODSː
The medical records of 15,591 patients who were diagnosed with DTC after
initial surgery in three medical centers (2000 to 2018) were reviewed
and 37 patients (test group) and 14 patients (validation group) with DM
and detailed clinicopathologic characteristics were identified. Patients
with no evidence of disease (NED) postoperatively were randomly sampled
to create a control group in a 4:1 ratio. RESULTSː Multiple
factors, including median age, extrathyroidal extension (ETE), AJCC
stage, position, histological type, and diameter differed significantly
between the DM and NED groups (P˂0.001) in univariate and multivariate
analysis. AJCC stage and diameter of the primary tumor made the greatest
contributions to prognosis according to decision-tree analysis and a
random forest algorithm. The predictive model constructed from these
data achieved 100% accuracy of classification. External validation
confirmed that this model has 100% accuracy of classification. In
addition, histology and ETE were found to be independent predictors of
survival in patients with metachronous metastases. CONCLUSIONSː
This study optimized the weight of risk factors, including AJCC stage
and diameter of primary tumor, in predicting DM in patients with DTC.
Our predictive model provides a strong tool for prediction that may
potentially affect clinical decision-making.
Real-world study of antifibrotic drugs-related adverse events based on the United States Food and Drug Administration Adverse Event Reporting System and VigiAccess databases
Authors: He Mneglin , Zhou Jian , Yang Taoran , Li Xuehan , Wang Rurong
Published: June 2023

Aims: To analyze and compare the adverse events (AEs) and adverse drug
reaction (ADRs) associated with pirfenidone and nintedanib, two
antifibrotic drugs commonly used in the treatment of idiopathic
pulmonary fibrosis (IPF), based on real-world data. Methods: We
collected reports from the FD Adverse Event Reporting System (FAERS) and
VigiAccess databases. Two main disproportional analysis, including
reporting odds ratio (ROR) and proportional reporting ratio (PRR), were
conducted to determine the association of these drugs with signals at
both the preferred term (PT) and system organ class (SOC) levels.
Results: A total of 55,949 reports for pirfenidone and 35,884 reports
for nintedanib were obtained from the FAERS database. Correspondingly,
the VigiAccess database provided 37,187 reports for pirfenidone and
23,134 reports for nintedanib. Male patients and individuals over the
age of 65 were more likely to report AEs for both drugs.
Gastrointestinal disorders emerged as the most significant signal at SOC
level for both pirfenidone and nintedanib. Additionally, signals such as
nausea, diarrhoea and decreased appetite were notable at PT level.
Furthermore, we also identified signals, including hemiplegic migraine
for pirfenidone and asthenia, constipation, as well as flatulence for
nintedanib, which were previously unknown or underestimated risks.
Conclusion: This study identified AEs and ADRs of pirfenidone and
nintedanib in the treatment of IPF, confirming the most of the
corresponding label information is relatively safe. However, some
unexpected risk signals should be taken seriously, and further research
is needed to manage the safety profiles of these drugs in IPF patients.
Tissue-specific expression of heterozygous Z-inversions in the zebra finch
Authors: Viitaniemi Heidi , Leder Erica , Lifjeld Jan , Kauzál Ondřej , Stopková Romana , Stopka Pavel , Albrecht Tomas
Published: June 2023

Chromosomal inversions have been identified in many natural populations
and can be responsible for novel traits and fast adaptation. In zebra
finch, an inversion in the Z chromosome has a pleiotropic effect on
multiple traits but especially on sperm. Males heterokaryotypic for the
inversion have sperm with a longer midpiece and higher velocity. They
have higher fertility and siring success than homokaryotypic males. To
understand the effect the Z inversion on these traits, we examined young
males at different stages of testis development using two homokaryotypic
lines and heterokaryotypes. We sampled both testis and liver tissue to
identify gene expression differences. In testis, 520 differentially
expressed genes were found and most of them were located on chromosome
Z. They were functionally enriched for sperm-related traits. In liver,
420 differentially expressed genes were not enriched for any specific
functions but showed also an overrepresentation on chromosome Z. In both
tissues, this overrepresentation was located near the distal end of Z
but also in the middle of the chromosome. For the heterokaryotype, we
observed several genes with expression patterns more similar to one or
the other karyotype, based on similarity to homokaryotype invidividuals.
This was confirmed with SNPs for three genes, and interestingly one
gene, dmgdh, had allele-specific expression originating from only one
inversion-allele in the testis, yet both inversion alleles were
expressed in the liver. This allele-specific difference in
tissue-specific expression demonstrates a pleiotropic effect of the
inversion and thus suggests a mechanism for divergent phenotypic effects
resulting from an inversion.
Intravenous Fluid Therapy and Hospital Outcomes for Vaso-Occlusive Episodes in Children, Adolescents, and Young Adults with Sickle Cell Disease
Authors: Haimed Abraham , Weiss Rebecca , Kwon Soyang , Bhat Rukhmi , Badawy Sherif
Published: June 2023

Background: While intravenous fluid (IVF) therapy in patients
with sickle cell disease (SCD) admitted for a vaso-occlusive episodes
(VOE) can help reduce red blood cell sickling, clinical practice varies
across institutions. We examined the relationship between IVF therapy
and hospital length of stay (HLOS), as well as adverse events, such as
acute chest syndrome (ACS), pediatric intensive care unit (PICU)
transfer and 28-day readmission. Methods: This is a
single-center retrospective analysis of SCD VOE hospitalizations between
January 2015 and April 2020. Patients with SCD, age 0-30, with
consecutive hospitalizations for VOE were included. For the first 3 days
of each admission, an “IVF ratio” was calculated by dividing actual
IVF rate administered by weight-based maintenance IVF (mIVF) rate.
Results: A total of 617 hospitalizations for 161 patients were
included. Mean HLOS was 5.7 days, (SD 3.9), and mean IVF volume over the
first 3 days of admission was 139.6 ml/kg/day (SD 57.8). Multivariate
analysis showed that for each additional 0.5 times the mIVF rate, HLOS
increased by 0.53 days (P<0.001; 95% CI: 0.609–0.989), but
there was no significant association between IVF therapy and adverse
events. History of chronic pain was associated with increased odds of
readmission (OR, 6.4; 95% CI: 3.93 – 10.52). Conclusions:
Despite the theoretical potential for IVF therapy to slow down the
sickling process, our findings suggest that increased IVF therapy was
associated with prolonged HLOS, which places a burden on patients,
families, and the health system.
Dynamics of oceanic slab tearing during transform-fault horizontally-oblique subduction: Insights from 3D numerical modeling
Authors: Xin Jie , Zhang Huai , Orellana-Rovirosa Felipe , Li Zhong-Hai , Liu Liang , Xu Yigang , Zhang Zhen , Shi Yaolin
Published: June 2023

Oceanic-plates vertical tearing is seismically-identified in the
present-day Earth. This type of plate tearing is frequently reported in
horizontally-oblique subduction zones where transform-faulted oceanic
plates are subducting (or subducted). However, the mechanisms behind
vertical slab tearing are still poorly understood, thus we utilize 3D
time-dependent Stokes’ flow thermo-mechanical models to further study
this problem. We find that (i) the age offset of transform fault and
(ii) the horizontal obliqueness of subduction fundamentally control the
tearing behavior of two generic, materially-homogeneous oceanic slabs
separated by a low-viscosity zone. The two slabs sequentially bend,
which combined with the age-thickness difference between slabs, causes
the differential sinking of them. Based on the modeling results,
well-developed slabs vertical tearing would happen when the oblique
angle of subduction is ≥30° or the age ratio of the secondly-bent to
firstly-bent slab being ~<0.6. Quantifying the
horizontal distance-vector between sinking slabs, we find that
subduction at medium-low horizontal-obliqueness angles (≤40°) of young
lithosphere (slabs-average ~15 Myr) tends to produce
fault-perpendicular tearing. Contrastingly, old-age slabs (average ≥ 30
Myr) with medium-large obliqueness angles
(~>20°) tend to produce fault-parallel
tearing, related to differential slab-hinge retreat or rollback.
Correlations between slabs’ (i) computed tearing horizontal-width and
(ii) scaling-theory forms of their subduction-velocity differences, are
reasonable (0.76-0.97). Our numerically-predicted scenarios are
reasonably consistent with plate-tear imaging results from at least 4
natural subduction zones. Our modeling also suggests that continual
along-trench variation in subduction dip angle may be related to a
special case of oblique subduction.
Predictions Vs Measurements Wavefield recovery and identification The experimental setup Aim of the study Velocity changes by the stretching method Conclusion
Authors: Bastide Thomas Gaubert , Bordes Clarisse , Garambois Stéphane , Brito Daniel , Collet Olivia , Voisin Christophe
Published: June 2023

In recent years, seismic-noise based methods have shown great potential
for the monitoring of various processes occurring in the Earth’s crust.
Among them, the fine detection of hydrological variations at different
scales is a major issue in the context of water resources management
(Gaubert-Bastide et al. 2022). In order to better understand the
sensitivity of continuous seismic wavefields to water content variations
affecting both saturated and unsaturated zones, we have set up a dynamic
and meter-scale laboratory experiment. This sandbox experiment
reproduces field surveys based on the recording and processing of
seismic background noise (hundred to kiloHertz range) in the context of
hydrological variations. These multiple measurements, which benefit from
independent measurements of pressure and water saturation at different
depths, allow us to refine the sensitivity of the seismic wavefield to
variations in water content and hysteretic behavior related to different
phases of imbibition/drainage.
Learning Closed-form Equations for Subgrid-scale Closures from High-fidelity Data: Promises and Challenges
Authors: Jakhar Karan , Guan Yifei , Mojgani Rambod , Chattopadhyay Ashesh , Hassanzadeh Pedram , Zanna Laure
Published: June 2023

There is growing interest in discovering interpretable, closed-form
equations for subgrid-scale (SGS) closures/parameterizations of complex
processes in Earth system. Here, we apply a common equation-discovery
technique with expansive libraries to learn closures from filtered
direct numerical simulations of 2D forced turbulence and Rayleigh-Benard
convection (RBC). Across common filters, we robustly discover closures
of the same form for momentum and heat fluxes. These closures depend on
nonlinear combinations of gradients of filtered variables (velocity,
temperature), with constants that are independent of the fluid/flow
properties and only depend on filter type/size. We show that these
closures are the nonlinear gradient model (NGM), which is derivable
analytically using Taylor-series expansions. In fact, we suggest that
with common (physics-free) equation-discovery algorithms, regardless of
the system/physics, discovered closures are always consistent with the
Taylor-series. Like previous studies, we find that large-eddy
simulations with NGM closures are unstable, despite significant
similarities between the true and NGM-predicted fluxes (pattern
correlations > 0.95). We identify two shortcomings as
reasons for these instabilities: in 2D, NGM produces zero kinetic energy
transfer between resolved and subgrid scales, lacking both diffusion and
backscattering. In RBC, backscattering of potential energy is poorly
predicted. Moreover, we show that SGS fluxes diagnosed from data,
presumed the ‘truth’ for discovery, depend on filtering procedures and
are not unique. Accordingly, to learn accurate, stable closures from
high-fidelity data in future work, we propose several ideas around using
physics-informed libraries, loss functions, and metrics. These findings
are relevant beyond turbulence to closure modeling of any multi-scale
system.
The impacts of Stratospheric Aerosol Injection on Antarctic ice loss depend on injection location
Authors: Goddard Paul Brent , Kravitz Ben , MacMartin Douglas G , Visioni Daniele , Bednarz Ewa M. , Lee Walker Raymond
Published: June 2023

Owing to increasing greenhouse gas emissions, the West Antarctic Ice
Sheet as well as a few subglacial basins in East Antarctica are
vulnerable to rapid ice loss in the upcoming decades and centuries,
respectively. This study examines the effectiveness of using
Stratospheric Aerosol Injection (SAI) that minimizes global mean
temperature (GMT) change to slow projected 21st century Antarctic ice
loss. We use eleven different SAI cases which vary by the latitudinal
location(s) and the amount(s) of the injection(s) to examine the
climatic response near Antarctica in each case as compared to the
reference climate at the turn of the last century. We demonstrate that
injecting at a single latitude in the northern hemisphere or at the
Equator increases Antarctic shelf ocean temperatures pertinent to ice
shelf basal melt, while injecting only in the southern hemisphere
minimizes this temperature change. We use these results to analyze the
results of more complex multi-latitude injection strategies that
maintain GMT at or below 1.5°C above the pre-industrial. All these cases
will slow Antarctic ice loss relative to the mid-to-late 21st century
SSP2-4.5 emissions pathway. Yet, to avoid a GMT threshold estimated by
previous studies pertaining to rapid West Antarctic ice loss
(~1.5°C above the pre-industrial), our study suggests
SAI would need to cool below this threshold and predominately inject at
low southern hemisphere latitudes. These results highlight the
complexity of factors impacting the Antarctic response to SAI and the
critical role of the injection strategy in preventing future ice loss.
A New GFSv15 based Climate Model Large Ensemble and Its Application to Understanding Climate Variability, and Predictability
Authors: Zhang Tao , Yang Weiyu , Quan Xiaowei , Zhu Jieshun , Jha Bhaskar , Kumar Arun , Hoerling Martin P. , Barsugli Joseph , Wang Wanqiu
Published: June 2023

NOAA Climate Prediction Center (CPC) has generated a 100-member ensemble
of Atmospheric Model Intercomparison Project (AMIP) simulations from
1979 to present using the GFSv15 with FV3 dynamical core. The intent of
this study is to document a development in an infrastructure capability
with a focus to demonstrate the quality of these new simulations is on
par with the previous GFSv2 AMIP simulations. These simulations are part
of CPC’s efforts to attribute observed seasonal climate variability to
SST forcings and get updated once a month by available observed SST.

The performance of these simulations in replicating observed climate
variability and trends, together with an assessment of climate
predictability and the attribution of some climate events is documented.
A particular focus of the analysis is on the US climate trend, Northern
Hemisphere winter height variability, US climate response to three
strong El Niño events, the analysis of signal to noise ratio (SNR), the
anomaly correlation for seasonal climate anomalies, and the South Asian
flooding of 2022 summer, and thereby samples wide aspects that are
important for attributing climate variability. Results indicate that the
new model can realistically reproduce observed climate variability and
trends as well as extreme events, better capturing the US climate
response to extreme El Niño events and the 2022 summer South Asian
record-breaking flooding than GFSv2. The new model also shows an
improvement in the wintertime simulation skill of US surface climate,
mainly confined in the Northern and Southeastern US for precipitation
and in the east for temperature.