bluuebunny/crossref_metadata_2025 huggingface dataset:
Cultivation, Yield, Income, and Tree Diversity in a Coffee Field in the Eastern Ghats of Andhra Pradesh, India
Authors: Ramalakshmana J. , Padal S. B.
Published: September 2022

In this study we analyse coffee cultivation, yield, revenue and tree diversity in coffee forest regimes in Eastern Ghats of Andhra Pradesh. The coffee growing regions in India are mainly confined to the traditional South Indian states that are Karnataka, Kerala and Tamil Nadu and partly in non-traditional regions are Andhra Pradesh and Odisha. While to a smaller extent in North-Eastern states. The production of coffee has an impact on the national and international economies and is the second-most traded commodity in the world. Total area under coffee plantations in Andhra Pradesh was about 4010 ha. The Average yield of Andhra Pradesh coffee is roughly 363.9026MT per year and the average revenue is 629.158(in lakhs) per year. Deforestation and the loss of biodiversity are two effects of the expansion of coffee farming. However, shade-grown coffee has been hailed as a way to safeguard tropical biodiversity. If promoted, shade-grown coffee can help preserve some biodiversity, but it can't match a natural forest's whole range of ecological advantages. The coffee cultivated in Andhra Pradesh is mainly shade grown coffee. In this study we also focused on tree species diversity, we analysed data on tree species diversity from 20 field plots (0.1 ha) in coffee area of, Eastern Ghats, Andhra Pradesh, India. We also analyse diversity indices evenness indices species richness indices and Density, frequency, basal area and IVI also calculated. Forest ecosystems can be protected against rising levels of disruption by increasing the diversity of tree species. The variety of tree species may also be directly impacted by anthropogenic disturbance.
The Effects of COVID-19 Pandemic on the Perceived Stress and Coping Strategies among Filipino Immigrants in America
Authors: Lofranco Farrezzel T.
Published: September 2022

The Filipinos in America are an at-risk group during the pandemic not only because of their exposure as health care workers but also due to the intersections of various factors like economic insecurity, pre-existing health conditions, a lack of health insurance, and the fact that tens of thousands of undocumented Filipinos. Also, Filipinos faced Asian hate during the pandemic. All the circumstances Filipinos in America faced amid the pandemic can contribute to perceived stress. Filipinos are also known to have good coping skills despite the adversities in life. However, not many studies specifically represent Filipino-Americans but rather Asian Americans collectively. This study sought to examine the effects of the COVID-19 pandemic on Filipinos' perceived stress and coping strategies in America. Using a descriptive inferential research design, this study revealed that the COVID-19 pandemic influenced the level of perceived stress and the coping strategies of the respondents. Also, it showed that there was a significant relationship between the respondents' profile and their level of perceived stress and coping strategies. The findings of this study can contribute to the development of Filipinos' knowledge-based mental health status in America. Also, this can be used for delivering effective treatment programs for Filipinos in America by different healthcare professionals.
Descending Necrotizing Mediastinitis as a Complication of Dental Cervical Cellulitis: A Case Report and Review
Authors: Haddari Fatima Zahra , Touzani Soumaya , Allani Linda El , Houari Nawfal , Bouazzaoui Abderrahim El , Boukatta Brahim , Kanjaa Nabil
Published: September 2022

Descending necrotizing mediastinitis remains a serious condition with a high mortality rate due to its often fulminant clinical presentation. An early diagnosis and a well conducted multidisciplinary therapeutic management are essential to reduce morbi-mortality. Delayed diagnosis, inappropriate antibiotic therapy, non-optimal surgical drainage or lack of surveillance may increase morbidity and mortality. We report the case of a descending necrotizing mediastinitis complicating a dental cervical cellulitis in a 27 year old female patient with a successful outcome.
The Pessimistic Existentialism of Arthur Shopenhauer: An Expository and Evaluative Study
Authors: O. P Rev. Fr. Joseph T. Ekong
Published: September 2022

This work interrogates the seeming ambivalence between Arthur Schopenhauer's existentialist pessimism and his advocacy for artistic, moral and ascetic forms of awareness, as means of managing the absurdities and frustrations of life. The objective of this work is to discover whether or not his apparently orthogonal positions can be reconciled in any way at all, and what that might portend for the contemporary philosopher. Schopenhauer's metaphysics and philosophy of nature led him to the doctrine of pessimism: the view that sentient beings, with few exceptions, are bound to strive and suffer greatly, all without any ultimate purpose or justification and thus life is not really worth living. Arthur Schopenhauer was among the first 19th century philosophers to contend that at its core, the universe is not a rational place. Inspired by Plato and Kant, both of whom regarded the world as being more amenable to reason, Schopenhauer developed their philosophies into an instinct-recognizing and ultimately ascetic outlook, emphasizing that in the face of a world filled with endless strife, we ought to minimize our natural desires for the sake of achieving a more tranquil frame of mind and a disposition towards universal beneficence. Often considered to be a thoroughgoing pessimist, Schopenhauer in fact advocated ways to overcome a frustration-filled and fundamentally painful human condition. He believed that the "will-to-life" (the force driving man to survive and to reproduce) was the driving forces of the world, and that the pursuit of happiness, love and intellectual satisfaction was essentially futile and anyway secondary to the innate imperative of procreation. This essay argues that phenomenologically, Schopenhauer had an “existentialist” orientation towards the spatio-temporal world that informed his pessimism, but also engenders further questions regarding the actual sincerity of his mental commitment to such a position.
The Ambiguity of Culture and the Effect it has on English as a Second Language (ESL) Students Living Abroad
Authors: Dover Nathan
Published: September 2022

Due to its ambiguous nature, culture is one of the most difficult human phenomenons to define. Sociologists and Linguists are continuously expanding the aspects of what constitutes culture in an effort to understand how our individual identities can coexist as simultaneous members of a global community. This paper analysed various theories and literature in relation to the concept of culture in an effort to determine the effect it has on English as a second language (ESL) students. It discovered that although spoken and written discourse is integral to succeeding in a community, there are several non-linguistic methods of communication that can help ESL students to participate and become accepted members of their chosen second language society. This paper also compared the differences between individual and collective cultures and the social and environmental impact they can have on its participants.
Monkeypox an Emerging Threat during COVID-19, Stigmatization and its Status in India: A Review
Authors: Wani Ajaz A. , Kumar Ashwani
Published: September 2022

Human monkeypox is a zoonotic orthopoxvirus disease with a presentation similar to the smallpox. The frequency and geographical spread of human monkeypox cases have increased recently in most countries of world. The disease is endemic in Democratic Republic of the Congo, Central and West Africa, but presently spread to other nations of the world including India that too when the whole world is facing the Covid -19 pandemic. In this article the author focus on the various parameters related to the monkeypox, present status and the stigmatization.
A STUDY OF CONSTITUTION OF INDIA
Authors: Shishir Kumar Dehury
Published: September 2022

The purpose of the paper is vision on the constitution of India is grounded on the principles of the fraternity, liberty, justice and equality. For completing goal, we have taken on a brief study of all the journals and the books which are connected with the necessities of the constitution manifest great esteem for the human dignity, pledge to equality and non-discrimination and, apprehension for the weaker section in the society. Additionally, the constitution makes it compulsory for the Govt. to protect and promote freedoms, and to guarantee every citizen a decent standard of the living. In other words, the Indian Constitution promises the rudimentary human rights to every citizen of India. This article dealt with the general Constitutional Laws of India and the amendments made into the Constitution of India. The article also exposes approximately the schemes for consciousness of the above-mentioned goals are confined in the Fundamental Rights enshrined in Part III and Part IV of the Constitution. “The right to freedom”, “the right against exploitation”, “the right to freedom of religion”, “cultural and educational right”, “right to constitutional remedies” and special necessities connecting to positive classes are some of the constitutional necessities guaranteeing human rights.
KEYWORDS: Constituent Assembly, Adequate Safeguards, Ex-Post Facto Laws, Justifiable.
Factores que influyen en la sexualidad de adolescentes que estudian medicina en una universidad privada, Cochabamba
Authors: Arias López Liseth Lourdes
Published: September 2022

La sexualidad es un eje importante, sobre todo en el periodo de la adolescencia, por los riesgos que suponen las prácticas sexuales para la salud, y es más significativo si nos referimos a estudiantes de medicina. Objetivo. Identificar los factores que moldean la sexualidad de jóvenes adolescentes que estudian medicina en una universidad privada de la ciudad de Cochabamba. Metodología. Para ello se efectuó un estudio cuantitativo, descriptivo, exploratorio y transversal a 253 jóvenes. El cuestionario estructurado contuvo 55 preguntas. Resultados. Existen diferencias en la sexualidad entre hombres y mujeres adolescentes, siendo que la edad de inicio de relaciones sexuales en los varones es más precoz que en las mujeres, además que los varones tienen una vida sexual más activa (58 %) que las mujeres (42 %). El análisis multivariado de sexualidad ajustado a las variables relacionadas con la actividad sexual entre los adolescentes están el sexo (p: 0,009), la religión (p: 0,001), el tipo de familia con la que conviven (p: 0,018), la situación sentimental (p: 33e-08). Discusión y conclusiones. La sexualidad y la educación sexual son diferentes en función al sexo del adolescente, en la misma magnitud en que los estereotipos son caracterizados de manera desigual en el imaginario cultural de los jóvenes universitarios.
PRIMARY IDENTIFICATION OF THE MICROBIOME OF KEFIR GRAINS FROM DIFFERENT TERRITORIAL ZONES AND THEIR FILM-FORMING ABILITY
Authors:   Federal State Budgetary Educational Institution of Higher Education «Lomonosov Moscow State University», Moscow, Russian Federation, Fan Ding ,   Shenzhen MSU-BIT University, Shenzhen, China, Krasilnikova Anna A. ,   Federal State Budgetary Educational Institution of Higher Education «Lomonosov Moscow State University», Moscow, Russian Federation, Stoyanova Lidiya G. ,   Federal State Budgetary Educational Institution of Higher Education «Lomonosov Moscow State University», Moscow, Russian Federation, Netrusov Alexander I. ,   Federal State Budgetary Educational Institution of Higher Education «Lomonosov Moscow State University», Moscow, Russian Federation; Faculty of Biology and Biotechnology, Higher School of Economics, Moscow, Russian Federation
Published: September 2022

From samples of kefir grains (KG) of home-made kefirs from different traditional territorial zones of their production and use: the Caucasus (North Ossetia), China (Tibet) and Russia (Moscow region), 2 species of lactobacilli were isolated and identified: Lactobacillus kefiri and L.casei, 3 yeast species Pichia fermentans (from Moscow), Yarrowia lipolytica and Pichia fermentans (from Tibet), Galactomyces candidus (from North Ossetia). The ability of the studied cultures to form biofilms was shown, which is an important indicator for the creation of sustainable probiotic microbial communities and functional food products needed during the coronavirus pandemic.
VETERINARY AND SANITARY ASSESSMENT OF BEE HONEY
Authors:   Moscow State University of Food Production, Moscow, Russian Federation, Kushch Irina V. ,   All-Russian Research Institute of Veterinary Sanitation, Hygiene and Ecology – Branch of Federal State Budget Scientific Institution «Federal Scientific Center – K.I. Skryabin, Ya.R. Kovalenko All-Russian Research Institute of Experimental Veterinary Medicine, Russian Academy of Sciences», Moscow, Russian Federation, Udavliev Damir I. ,   Moscow State University of Food Production, Moscow, Russian Federation; All-Russian Research Institute of Veterinary Sanitation, Hygiene and Ecology – Branch of Federal State Budget Scientific Institution «Federal Scientific Center – K.I. Skryabin, Ya.R. Kovalenko All-Russian Research Institute of Experimental Veterinary Medicine, Russian Academy of Sciences», Moscow, Russian Federation, Bairov Anton L. ,   Central Scientific and Methodological Veterinary Laboratory, Moscow, Russian Federation
Published: September 2022

The article presents data of studies conducted from 2019 to 2021 on physicochemical and organoleptic indicators, the determination of pesticides, antibiotics and other drugs. The main methods for determining the safety of beekeeping products and regulatory documents regulating the quality of manufactured products are also considered. According to the results of the study, 98% of bee honey in the territory of the Russian Federation met the requirements of the Technical Regulations of the Customs Union TR CU 021/2011 «On food safety», which indicates the high quality of the products.
Perancangan Sistem Pembayaran Sekolah pada SMK ZZZ Menggunakan Metode Waterfall
Authors: Sugiyatno Sugiyatno
Published: September 2022

Tujuan penelitian ini adalah untuk membangun sebuah sistem informasi pembayaran pada salah satu SMK ZZZ di Bekasi. Permasalahannya mengapa perlu pengembangan sistem, karena proses pembayaran selama ini masih dilakukan secara konvensional yang mempengaruhi proses pelayanan memerlukan waktu lebih lama. Untuk membangun mengembangkan sistem menggunakan metode waterfall yang merupakan salah satu dari metode pengembangan sistem yang dikenal dengan Software Development Life Cycle (SDLC). Tahapan metode waterfall adalah mengkomunikasikan dengan pemilik proyek dalam hal ini sekolah, merencanakan kebutuhan dengan mengumpulkan data dan menganalisa, membuat model dari perangkat lunak terhadap aliran data dan control, proses-proses fungsional, tingkah laku operasi dan informasi-informasi yang terkandung di dalamnya, mengkodekan dalam hal ini peneliti menggunakan PHP (Hypertext Preprocessor) dengan Database MySQL serta melakukan pengujian terhadap sistem. Terdapat 3 (tiga) actor dalam aplikasi ini yaitu Admin, Petugas Staff Tata Usaha dan Siswa/wali murid. Aktivitas dari sistem ini antara lain Pembayaran SPP, Kelola Data Siswa, Kelola Data Kelas, Kelola Data Petugas, Transaksi Pembayaran oleh Admin, Buka Histori Pembayaran, Laporan
Sistem Pendukung Keputusan Cerdas Menggunakan Metode Ant Colont Optimization (ACO) untuk Pencarian Jalur Optimum Rantai Pasok Bioenergi Berbasis Kelapa Sawit
Authors: Maryani Rina
Published: September 2022

The concept of supply chain management in business activities is very necessary. This concept involves more than one type of company. One of the businesses that requires this concept is palm oil-based bioenergy management. The optimal path in the supply chain network is very difficult, because the product supply chain network is perishable. For that we need an intelligent decision support system model in the search for the optimal path. The purpose of this study is to determine the optimum value and to find the optimum path of the palm oil-based bioenergy supply chain. The method used in the development of the model is the ant colony optimization method, namely the shortest path method. The data processed is the distance and time of supply. The optimal path search result is 0.035. So that this research becomes a reference in determining the optimal path.
Analisis Trend Saham LQ-45 selama Pandemi Covid-19 dengan K-Means Clustering
Authors: Hanjasto Prima
Published: September 2022

Stocks are one of the investment instruments that have great risks and benefits. Large profits in a very fast time often make investors forget about the risks that may occur. Dynamic price changes at any time require in-depth analysis to determine the decision to buy, hold or sell. The COVID-19 pandemic has had a major effect on economic growth, investment and culture. This study aims to group stocks that have the same trend during the pandemic so that they can get returns and minimize the risk of loss. The stock price data in this study is sourced from finance.yahoo.com with a time span from 2019 to 2021. The stocks to be analyzed are stocks belonging to the LQ-45 stock category from 2019 to 2021. will be grouped with K-means Clustering. This study groups LQ-45 stocks into 3 clusters which are the right considerations by investors in stock investments during the Covid-19 pandemic.
Effects of (COVID)-19 Pandemic on Tourism Businesses in India: Operational and Strategic Measures Undertaken for Survival
Authors: Aggarwal Prachi Jain , Singh Kaurav Rahul Pratap , Gursoy Dogan
Published: September 2022

This study employs a qualitative research approach based on the premises of the Grounded Theory method to identify the impact of COVID-19 on travel businesses, especially on travel agencies, in India and investigates the various operational and strategic measures undertaken by those
businesses to survive during the pandemic. Data for this study were collected from 40 travel agency businesses in India through structured interviews of representatives from various travel agencies and from secondary data sources such as interview articles, newspaper reports, and blogs. The
results highlight the impacts of the pandemic on travel agency businesses and the measures being taken by those businesses to survive in the short run, sustain in the medium run, and thrive in the long run. Findings provide critical insights on the operational and strategic measures for policymakers
and other stakeholders of the travel and hospitality industry for effective management and comeback from the pandemic’s effects. This research extends previous studies by focusing more specifically on tourism business organizations with different modes and scales of operations.
The Impact of the (COVID)-19 Crisis on Tourism Development in Peripheral Areas in Austria
Authors: Sandriester Jasmin , Kern Carmen , Harfst Jörn
Published: September 2022

COVID-19 has greatly influenced and restricted people’s everyday lives worldwide, especially the freedom to travel and engage in tourism. In Austria, tourism contributes 7.5% to the country’s GDP, ranking it in the top one third of EU countries. Hence, the consequences of
the pandemic have been significant. However, in contrast to the overall declining numbers in arrivals and overnight stays, domestic tourism has experienced a revival compared to 2019, with a +22.6% increase in overnight stays by Austrian guests in August 2020. Nevertheless, these
trends have been unevenly distributed across Austrian regions. As the long-term consequences of COVID-19 on tourism are unclear, this article aims to provide a snapshot by analyzing the pandemic’s impact on selected Austrian regions as well as the district of Leoben, a small and peripheral
tourism region. Based on quantitative and qualitative research, the article highlights the uneven geographical character of COVID-19’s impact on tourism and shows that more peripheral regions have indeed experienced short-term gains in regard to their visitor numbers–especially strengthening
existing peaks. Nevertheless, there are questions regarding the sustainability of these trends because of the intrinsic deficits of these regions in terms of infrastructure and management capacities. Future research in this field should consider the unevenness of COVID-19’s impact while
also analyzing (long-term) changes related to peripheral regions and their tourism development in post-COVID-19 times. A microanalysis on a municipal level could also be beneficial.
(COVID)-19 and the Impact on Cultural Tourism: The Case of Beit She'An Valley, Israel
Authors: Sofer Michael , Shmuel Irit , Amit-Cohen Irit , Tchetchik Anat , Shiff Shilo , Michael Yaron
Published: September 2022

Under the COVID-19 (SARS-CoV-2) pandemic in Israel, almost every taken-for-granted feature of the day-to-day life was affected. This phenomenon and its derived socioeconomic effects on cultural tourism have been investigated in a northern peripheral area, Beit She’an Valley, which
includes a small urban municipality, Beit She’an town, and a regional council, Emek HaMaayanot (a rural municipality). The closure of heritage sites and almost every kind of public cultural venue has led to economic consequences such as absence of tourists, worker layoffs in the cultural
tourism industry, and a wave of collapse of businesses. In order to understand the implications of the pandemic on the area, surveys were conducted among two local groups: business owners and residents. The findings show that 9 out of 10 businesses have been affected, yet few have received
governmental support. A large number of business owners think that under the current circumstances, their business can be sustained only for several months. Residents reported that during the pandemic, they avoided public spaces and gatherings, visiting cultural sites much less often than
before the pandemic. It is clear that both groups have to readjust their perception of tourist spaces and their activities. The changes that took place in tourism activities following the pandemic have led the owners of local businesses related to cultural tourism, as well as tour guides,
to think of different ways to operate their activities. Interviews with a group of business owners suggest that new initiatives and survival strategies may have far-reaching implications for cultural tourism in the region and its characteristics. The findings of this research yield several
recommendations regarding how to deal with similar crises in the future so that tourism activities at heritage sites will not be harmed.
ЕФЕКТИВНІСТЬ КОМБІНОВАНОЇ ІМУНОТЕРАПІЇ ПРОПЕСОМ ТА ІНФЛАМАФЕРТИНОМ ПРИ ВИБІРКОВОМУ ДЕФІЦИТІ NK- І NKT-КЛІТИН У ДОРОСЛИХ ПАЦІЄНТІВ З ГЕНЕТИЧНИМ ДЕФІЦИТОМ ФОЛАТНОГО ЦИКЛУ
Authors: Стефанишин Володимир Михайлович , Мальцев Дмитро Валерійович
Published: September 2022

Обґрунтування. Результати попередніх клінічних досліджень вказують на потенційну користь від комбінованої імунотерапії Пропесом та Інфла-мафертином для компенсації дефіциту NK- і/або NKT-клітин, зумовленого генетичним дефіцитом фолатного циклу (ГДФЦ), у дітей з розладами спектру аутизму.

Мета дослідження: вивчити ефективність комбінованої імунотерапії Пропесом та Інфлама-фертином при дефіциті NK- і/або NKT-клітин у дорослих з ГДФЦ.

Матеріали і методи. В даному одноцентровому ретроспективному контрольованому нерандомізованому клінічному дослідженні проаналізовано дані медичних карток 212 дорослих пацієнтів віком від 19 до 50 років з ГДФЦ (досліджувана група, ДГ). Пацієнти ДГ отримували Пропес в дозі 2 мл в/м через день на ніч протягом 3 місяців підряд (45 ін’єкцій) та Інфламафертин в дозі 2 мл в/м через день на ніч протягом 3 місяців підряд, чергуючи з Пропесом (45 ін’єкцій). Контрольну групу (КГ) склади 34 пацієнти аналогічного вікового і гендерного розподілу з ГДФЦ, однак не отримували імунотерапії.

Результати та їх обговорення. Кількість NK-клітин досягла нижньої межі норми у 95 із 131 пацієнта (72% випадків) з вихідним дефіцитом цих лімфоцитів, а середня кількість NK-клітин в крові в ДГ збільшилася майже вдвічі протягом 3-місячного курсу імунотерапії (р<0,05; Z0,05; Z>Z0,05). Кількість NKT-клітин нормалізувалася у 136 із 174 пацієнтів (78% випадків) з вихідним дефіцитом цих клітин, а середня кількість NKT-клітин в крові в ДГ зросла під час курсу імунотерапії наполовину (р<0,05; Z<Z0,05) і продовжувала зростати протягом 2-х наступних місяців після відміни імунотропних препаратів (р<0,05; Z<Z0,05). Відзначалася спряженість між проведенням імунотерапії та нормалізацією кількості NK- (χ2=22,786; OR=11,215; 95%CI=3,534-35,590) і NKT-клітин (χ2=34,238; OR=9,54; 95%CI=4,094-22,247) в крові з середнім зв’язком між цими процесами (критерій φ=0,387 i 0,407 відповідно; С=0,361 і 0,377 відповідно).

Висновки. Комбінована імунотерапія за допомогою Пропесу та Інфламафертину – ефективна стратегія лікування імунодефіциту, зумовленого ГДФЦ, у дорослих пацієнтів.
ПРОТЕОЛІЗ У ПАТОГЕНЕЗІ АЛЕРГОЛОГІЧНОГО ЗАХВОРЮВАННЯ
Authors: Гарєєв Олексій , Кравець Тетяна , Лобанова Катерина
Published: September 2022

У дослідженні наведено результати оцінки культивування мікроорганізмів, що входять до складу транзиторної та нормофлори кишківника людини, з білками, екстрагованими з продуктів харчування, що складають щоденний раціон. В експеримент було залучено: екстракти білків коров’ячого молока, курячого жовтка, курячого білка, сої, пшениці, арахісу. Всі штами мікроорганізмів є пробіотичними, які у якості біологічно активних добавок (БАД) різними прописами широко використовуються як засоби терапії. Було отримано підтвердження участі позаклітинних протеолітичних ферментів мікроорганізмів у деструкції харчових білків. Відзначено вибірковість впливу ферментів одного штаму на різні харчові білки; участь у гідролізі конкретного білка протеаз штамів різних таксономічних груп.
ФЕНОТИПІЧНІ ОСОБЛИВОСТІ КЛІТИН ІМУННОЇ СИСТЕМИ У ВАГІТНИХ ЖІНОК, ЯКІ МАЛИ БЕЗПЛІДДЯ РІЗНОГО ГЕНЕЗУ В АНАМНЕЗІ
Authors: Коломієць Олена Володимирівна , Туманова Лариса Євгеніївна , Холод Валерія Володимирівна , Величко Марина Борисівна
Published: September 2022

Вступ. Комплексні клініко-лабораторні дослідження вагітних жінок з вивченням стану їх імунної системи — CD-фенотипу, в тому числі експресією внутрішньоклітинних цитокінів, є актуальними і важливими для розробки тактики спостереження і терапії, особливо у випадках безплідності в анамнезі.

Мета роботи – визначення особливостей рівнів імунокомпетентних клітин крові на основі CD-фенотипа з експресією внутрішньоклітинних цитокінів у вагітних жінок із безпліддям різного генезу в анамнезі.

Матеріали і методи. За допомогою клітинного цитофлуориметра FACSCan (Becton Dickinson, США) і тест-систем Becton Dickinson (США) визначали особливості імунітету з використанням моноклональних антитіл (МКА) до диференційованих антигенів лімфоцитів CD3, CD4, CD8, CD19, CD56, маркерів активації (HLA-DR, CD25, CD69), а також внутрішньоклітинну експресію цитокінів (IFN-γ, TNF-α, IL-4 і IL-10) CD3+CD4+-клітинами, у 436 не вагітних (референтна група n), 280 здорових вагітних без ускладненого анамнезу (група N) та 88 вагітних жінок із безпліддям різного генезу в анамнезі.

Результати. Проведені дослідження імунної системи вагітних жінок із ендокринним (1 гр.), перитонеальним (2 гр.) чи поєднаним (ендокринним і трубнозапальним труб-перитонеальним) (3 гр.) характером безпліддя в анамнезі виявили достовірне підвищення у жінок з хронічними інфекціями (2 гр.), порівняно з нормою у не вагітних, відносних рівнів CD3+ та CD3+CD4+-лімфоцитів з високою експресію у них маркерів активації HLA-DR та CD25, так само як і активації CD3+CD8+-, NK T CD3+CD4+CD56+- та CD3-CD56+-лімфоцитів за експресією ними антигенів гістосумісності ІІ класу. Показано також підвищення в порівнянні з здоровими не вагітними, на відміну від інших двох груп, функціональної активності Т-хелперів по продукції прозапальних цитокінів за даними експресії у них відповідних маркерів (IFN-γ+ та TNF-α+) в групі вагітних жінок з безпліддям запального генезу в анамнезі; експресія протизапальних IL-4 та IL-10 не відрізнялась він норми в усіх 3-х групах. Фенотипічні особливості імунокомпетентних клітин пацієнток із запальним безпліддям в анамнезі, так само як і інших двох груп, не відрізняються від здорових вагітних в ці терміни часу (6-10 тижнів), за винятком зниження рівнів у них CD3+CD4+IL-10+-лімфоцитів, що може бути прогностично небезпечним для зберігання нормального про-/протизапального цитокінового балансу.

Висновки. У обстежених всіх груп з ускладненим анамнезом в 1 триместрі досліджені показники не відрізняються від здорових вагітних на тих самих строках, але у жінок із трубно-перитонеальними запальними гінекологічними захворюваннями в анамнезі більш висока, порівняно з не вагітними, активація Т-кілерів, Т-цитотоксичних, натуральних кілерів і Т-хелперів/індукторів, в тому числі за внутрішньоклітинною секрецією прозапальних цитокінів IFN-γ і TNF-α, з достовірним зниженням — протизапального IL-10 при порівнянні з двома іншими групами.
Transfer Learning Model Training Time Comparison for Osteoporosis Classification on Knee Radiograph of RGB and Grayscale Images
Authors: Abubakar Usman Bello , Boukar Moussa Mahamat , Adeshina Steve , Dane Senol
Published: September 2022

In terms of financial costs and human suffering, osteoporosis poses a serious public health burden. Reduced bone mass, degeneration of the microarchitecture of bone tissue, and an increased risk of fracture are its main skeletal symptoms. Osteoporosis is caused not just by low bone mineral density, but also by other factors such as age, weight, height, and lifestyle. Recent advancement in Artificial Intelligence (AI) has led to successful applications of expert systems that use Deep Learning techniques for osteoporosis diagnosis based on some modalities such as dental radiographs amongst others. This study uses a dataset of knee radiographs (i.e., knee-Xray images) to apply and compare the training time of two robust transfer learning model algorithms: GoogLeNet, VGG-16, and ResNet50 to classify osteoporosis. The dataset was split into two subcategories using python opencv library: Grayscale Images and Red Green Blue (RGB) images. From the scikit learn python analysis, the training time of the GoogLeNet model on grayscale images and RGB images was 42minutes and 50 minutes respectively. The VGG-16 model training time on grayscale images and RGB images was 37 minutes and 44 minutes respectively. In addition, to compare the diagnostic performance of the two models, several state-of-the-art neural networks metric was used.
Evaluation of Hand Hygiene Facilities and Compliance of Healthcare Workers at The University of Medical Sciences Teaching Hospital, Ondo
Authors: Alao Oluwaseun Iretiayo , Farotimi Adekunbi Abosede
Published: September 2022

Hand Hygiene (HH) is the leading measure for preventing the spread of pathogens and reducing health care associated infections, health care providers’ adherence to recommended practices remains suboptimal in most settings, and maintaining its standards is difficult to sustain. However, Healthcare-associated infections (HAIs) remain the most common adverse event in healthcare, resulting in a significant burden on patients, their families, and health care systems. This study examines evaluation of hand hygiene facilities and compliance of health care workers at the University of Medical Sciences Teaching Hospital, Ondo. This was a cross-sectional descriptive study that was made up of 324 participants. Multi-stage sampling technique was used for the selection of participants. Self-administered questionnaire and observational checklists were used as tools for data collection. The reliability value of the questionnaire eliciting responses on self-reported compliance to hand hygiene technique techniques ranges from 0.703 to 0.764. Data were analysed using SPSS version 27. Inferential statistics of Chi Square was used test the hypothesis generated at 0.05 level of significance. The results revealed that none of the wards met the standard for hand hygiene facilities set by the WHO. 83.3% of the units had no poster or written policy on HH; 87% did not have alcohol-based hand rubs; 100% had at least one handwash sink; 100% had flowing tap water all day; and 100% had no hand drying facilities. Assessment of self-reported hand hygiene compliance showed that 86.42% of the respondents have good compliance to hand washing technique guideline with a mean score is 23.72 of 27 (87.85%) and 90.1% of the respondents have good compliance to hand hygiene using alcohol-based hand rub technique with a mean score is 19.68 of 21 (93.71%). A total of 1,016 hand hygiene opportunities were observed during the three-week period with an overall compliance rate of 29.9%. The compliance rate among nurses (31.2%) is higher than among doctors (21.8%). In recorded hand hygiene actions, hand washing is used slightly more frequently than alcohol-based hand rubs. The use of gloves is a major reason for missed opportunities in hand hygiene, responsible for 39.3% of missed opportunities.The study concluded that the availability of hand hygiene facilities and HCWs compliance at the University of Medical Sciences Teaching Hospital, Ondo is poor. The study also confirmed that while the self-reported hand hygiene compliance is high, the observed compliance with hand hygiene techniques is low. Specific measures such as improved facilities, training and monitoring are needed to improve HH compliance.
Building a Bridge Between Spirituality/Religion with Acceptance and Commitment Therapy
Authors: YAVUZ Oğuzhan
Published: September 2022

This study provides a framework for acceptance and commitment therapy (ACT) and draws attention to the points that ACT shares with spiritual/religious traditions. The paper first presents the history of the theory, its view of human nature, its basic concepts, and the emergence of ACT while ACT’s theoretical foundations, functional analysis of behavior theory, relational framework theory, and functional contextualism theory are presented as tables. The paper then explains the shared points between ACT and spiritual/religious approaches and diScusses how basic processes of the two can be combined. It then considers the spiritual/religious-oriented methods and techniques that can be used in ACT. The conclusion highlights the differences between ACT and other therapy approaches and the themes it shares with spiritual/religious approaches. Drawing on this study and ACT philosophy, new models could be developed that take into account the Islamic belief system specific to Turkish culture.
Special Issue on the Application of Machine Learning and Artificial Intelligence in Fault Diagnostics
Authors: Gryllias Konstantinos , Wang Tianyang , Shao Haidong
Published: September 2022

The rapid development of data science and associated artificial intelligence (AI) methods has seen a substantial increase in interest in their application to anomaly detection, fault diagnostic, and prognostic challenges across a wide range of industrial and civil applications. Such approaches may well be the complement that is sought for conventional physical model-based and statistical approaches which often struggle to achieve the desired performance when dealing with complex engineering systems. Researchers have started to apply a range of machine learning and AI-based methods to the large-scale, multi-dimensional data that is often associated with large-scale sensor systems, particularly those which involve IoT devices. There is clear scope for the further development of such approaches, such as deep learning, transfer learning methods, and AI models, to enhance the performance of condition monitoring and associated technologies, and this is the key motivation for this Special Issue. This Special Issue on the Application of Machine Learning and Artificial Intelligence in Fault Diagnostics contains 6 papers.
Variedades Castillo® Zonales. Resistencia a la roya con mayor productividad.
Authors: Flórez Claudia Patricia , Arias Juan Carlos , Cortina Hernando Alfonso , Moncada María del Pilar , Quiroga-Cardona Julio , Molina Diana María , García-López Juan Carlos
Published: September 2022

Las variedades Castillo® se desarrollaron a partir del cruzamiento de Caturra x Híbrido de Timor 1343, utilizando la diversidad genética como estrategia para tener una resistencia durable contra la roya del cafeto.
The complete mitochondrial genome of Montipora vietnamensis (Scleractinia, Acroporidae)
Authors: Wang Wei , Cao Bingbing , Xu Ziqing , Jia Zhiyu , Yu Shuangen , Tian Peng , Niu Wentao , Xiao Jiaguang
Published: September 2022

Montipora vietnamensisVeron, 2000 (Cnidaria, Anthozoa, Scleractinia, Acroporidae) is an uncommon, but distinctive species of stony coral. The complete mitochondrial genome ofM. vietnamensiswas sequenced in this study for the first time, based on 32 pairs of primers newly designed according to seven species in the family Acroporidae. The mitogenome ofM. vietnamensishas a circular form and is 17,885 bp long, including 13 protein-coding genes (PCGs), 2 tRNA (tRNAMet, tRNATrp), 2 rRNA genes and a putative control-region. The base composition of the complete mitogenome was 24.8% A, 14.2% C, 24.2% G and 36.8% T, with a higher AT content (61.6%) than GC content (38.4%). Based on 13 protein-coding genes, a Maximum Likelihood phylogenetic analysis showed thatM. vietnamensisis clustered in the genusMontiporawhich belongs to the family Acroporidae. More stony coral species should be sequenced for basic molecular information and to help confirm the taxonomic status and evolutionary relationships of Scleractinia in the future.
Quelle évolution pour le Système monétaire international ?
Authors: Artus Patrick , Gravet Isabelle
Published: September 2022

Est-ce que le dollar va rester la monnaie de réserve dominante, malgré l’endettement excessif des États-Unis, et en l’absence d’un substitut crédible au dollar ? Est-ce que la politique monétaire des États-Unis continuera à privilégier les situations domestiques sans tenir compte des externalités sur les pays émergents ? Est-ce que le financement extérieur des États-Unis va devenir plus difficile ? Ce qui entraînerait une dépréciation du dollar, avec la forte hausse de l’endettement extérieur des États-Unis, la volonté de l’Europe de conserver son épargne pour investir, avec la volonté des pays émergents de limiter les sorties de capitaux. Ou bien allons-nous rentrer dans un nouveau système pour limiter la variabilité déstabilisante des flux internationaux de capitaux : contrôles sélectifs des capitaux, réaction plus forte des politiques monétaires aux taux de change ? Est-ce que le Système monétaire international va continuer à se privatiser avec un rôle accru des flux de capitaux en actions, et donc de l’attractivité des entreprises, par rapport aux flux de capitaux en dettes publiques ? Ce papier tente de répondre à ces différentes questions qui sont cruciales pour l’avenir du système financier international. Classification JEL : E4, E5, E58, F3
Adverse Childhood Experiences, Family Support, and Depression: Evidence from Internal Migrants in China
Authors: Wu Shuqin , Wang Cen , Jiang Junfeng , Kelifa Mohammedhamid Osman , Wang Xinyu , Zheng Chen , Wang Peigang
Published: September 2022

Previous studies have linked poor family support and adverse childhood experiences (ACEs) to increased risk of depression; however, little is known about the interplay between the two when it comes to their effects on depression. Therefore, the current study examined if family support moderated the cumulative effect of ACEs on depression. Based on data from a migrant survey in Shiyan, Hubei Province, in 2019 (N= 1,326), this study used the ordinary least squares method to analyze the effect of ACEs on depression and evaluate whether family support moderated this effect. Higher exposure to ACEs and lower scores of family support were associated with higher depression levels in adulthood. The moderation model indicated that family support significantly moderated the relationship between ACEs and depression. Appropriate interventions to reduce depression should target internal migrants with history of ACEs. Community nurses should consider ACEs as an integral part of psychosocial assessment. Negative effects of ACEs can be reduced through teaching skills that increase effective family interaction and maintain supportive family networks. [Journal of Psychosocial Nursing and Mental Health Services, 61(3), 19–25.]
Corneal Epithelium Thickness and Refractive Changes After Myopic Laser Corneal Refractive Surgery
Authors: Canto-Cerdan Mario , El Bahrawy Mohamed , Alió Jorge L. , Casanova Laura , García María J. , Al-Amri Saad Abdulrahman J. , Cavas Francisco , Alió del Barrio Jorge L.
Published: September 2022

PURPOSE:

To evaluate the postoperative changes in corneal epithelium thickness and refractive power after femtosecond laser–assisted laser in situ keratomileusis (LASIK) and small incision lenticule extraction (SMILE) for myopia correction using anterior segment optical coherence tomography (OCT) with an integrated Placido disc topographer.

METHODS:

The VisuMax 500-kHz femtosecond laser (Carl Zeiss Meditec AG) and Amaris 750 excimer laser (SCHWIND eye-tech-solutions) were used. Central, paracentral, and 6-mm epithelial thickness values were obtained, and the change in the value of epithelial thickness was calculated. Changes in the refractive power of the epithelium were also evaluated. The repeatability of this new measurement was also analyzed using the intraclass correlation (ICC). The total follow-up period was 6 months.

RESULTS:

A total of 77 LASIK eyes were matched with 77 SMILE eyes. Mean spherical equivalent was −3.92 ± 1.67 diopters (D) for LASIK versus −4.02 ± 1.63 D for SMILE (
P
= .356). Epithelial thickness parameters significantly and equally thickened in both types of surgery. The change in the value of epithelial thickness was positively correlated with spherical aberration. Analysis of the refractive power of the corneal epithelial layer (ICC > 0.70) showed a tendency for the postoperative myopization of the refractive component of this layer (−0.11 D for SMILE and −0.53 D for LASIK at 3 mm) and an increase in its cylinder and aberrometry. Increasing postoperative spherical aberration and epithelial thickness increased myopization of the epithelial refractive sphere (
P
< .05).

CONCLUSIONS:

Corneal epithelium thickens similarly after LASIK and SMILE, being slightly higher after SMILE. This correlates with the induced spherical aberration. Corneal epithelium thickening induces myopization of its refractive power, which accounts for a slight regression of the net refractive power change on the treated cornea.

[
J Refract Surg
. 2022;38(9):602–608.]
Strengthening Health Literacy of Vulnerable Groups—Introduction of Two New Modules Within the Communal Health Guides Intercultural in Frankfurt am Main Project
Authors: Schade Manuela , Lang Sarah Alexandra , Stenzel Sophia
Published: September 2022

Health literacy is limited among most of the German population. Among vulnerable groups, including people with a migration history, it is necessary to provide support. Thus, the public health department of the city of Frankfurt am Main initiated a project called communal health guides intercultural [Kommunale Gesundheitslotsen interkulturell] where health guides are trained to strengthen the health literacy of people with a migration background as well as of people with poor socioeconomic living conditions. Health guides are trained on specific health topics to pass on their knowledge as multipliers in different target groups. We are introducing two new modules complementing the existing health guide project from conceptualization to evaluation. The first module aims to strengthen health literacy among parents of children younger than age 10 years and the second module addresses inhabitants of community accommodations and aims to improve health communication and information, currently focusing on coronavirus disease 2019 and vaccinations. Another aim of the two modules is to find out the specific information needs of the target populations. The newly added modules aim to reduce health inequities for all citizens of Frankfurt am Main. [

HLRP: Health Literacy Research and Practice
. 2022;6(3):e239–e246.

]

Plain Language Summary:

Health literacy is often limited among the German population. Especially for socially disadvantaged groups, the public health department of the city of Frankfurt am Main would like to provide support. A project called Communal Health Guides Intercultural was initiated. Health leaders are trained to strengthen the health literacy of people who are socially disadvantaged. This project consists of two modules. One module is aimed at parents of children younger than age 10 years; the other module is aimed at residents in community accommodation. The project aims to reduce health inequities.
Remarks on parabolic equation with the conformable variable derivative in Hilbert scales
Authors: Duc Phuong Nguyen , Akdemir Ahmet Ocak , Nguyen Van Tien , Nguyen Anh Tuan
Published: September 2022

In this paper, we are interested in diffusion equations with conformable derivatives with variable order. We will study two different types of models: the initial value model and the nonlocal in time model. With different values of input values, we investigate the well-posedness of the mild solution in suitable spaces. We also prove the convergence of mild solution of the nonlocal problem to solutions of the initial problem. The main technique of our paper is to use the theory of Fourier series in combination with evaluation techniques for some generalized integrals. Our results are one of the first directions on the diffusion equation with conformable variable derivative in Hilbert scales.
Adverse Effects of Air Pollution on Pulmonary Diseases
Authors: Ko Ui Won , Kyung Sun Young
Published: September 2022

Environmental exposure to air pollution is known to have adverse effects on various organs. Air pollution has greater effects on the pulmonary system as the lungs are directly exposed to contaminants in the air. Here, we review the associations of air pollution with the development, morbidity, and mortality of pulmonary diseases. Short- and long-term exposure to air pollution have been shown to increase mortality risk even at concentrations below the current national guidelines. Ambient air pollution has been shown to be associated with lung cancer. Particularly long-term exposure to particulate matter with a diameter <2.5 μm (PM2.5) has been reported to be associated with lung cancer even at low concentrations. In addition, exposure to air pollution has been shown to increase the incidence risk of chronic obstructive pulmonary disease (COPD) and has been correlated with exacerbation and mortality of COPD. Air pollution has also been linked to exacerbation, mortality, and development of asthma. Exposure to nitrogen dioxide (NO2) has been demonstrated to be related to increased mortality in patients with idiopathic pulmonary fibrosis. Additionally, air pollution increases the incidence of infectious diseases, such as pneumonia, bronchitis, and tuberculosis. Furthermore, emerging evidence supports a link between air pollution and coronavirus disease 2019 transmission, susceptibility, severity and mortality. In conclusion, the stringency of air quality guidelines should be increased and further therapeutic trials are required in patients at high risk of adverse health effects of air pollution.