bluuebunny/crossref_metadata_2025 huggingface dataset:
Sistem Informasi Apotek Terintegrasi dengan Memanfaatkan Storage Cloud System
Authors: Ramadhan Muhammad Farhan , Suprianto Suprianto , Kautsar Irwan Alnarus , Sumarno Sumarno
Published: August 2024

Apotek Tiara di Surabaya, meskipun memiliki jaringan cabang yang luas, menghadapi tantangan dengan sistem transaksi offline yang membutuhkan transfer data fisik melalui flash drive, menyebabkan keterlambatan dalam pembaruan di seluruh cabang. Studi ini bertujuan untuk mengatasi ketidakefisienan ini dengan merancang sistem terintegrasi menggunakan penyimpanan cloud untuk memfasilitasi pembaruan data secara instan melalui platform online. Menggunakan metode waterfall, model umum dalam Siklus Hidup Pengembangan Sistem (SDLC), penelitian ini berlangsung melalui tahapan analisis, desain, implementasi, pengujian, dan pemeliharaan. Sistem yang diterapkan secara signifikan meningkatkan efisiensi sinkronisasi data, seperti yang dibuktikan oleh tes replikasi Master Slave yang sukses, memastikan pembaruan data yang cepat dan pengelolaan IP dinamis antara database master dan slave. Penelitian ini mengonfirmasi efektivitas sistem berbasis cloud dalam meningkatkan manajemen data dan efisiensi operasional dalam pengaturan farmasi.
Perancangan Aplikasi Marketplace Toko Tani Indonesia Center Berbasis Web
Authors: Hermawan Rafel Ardinata , Azinar Azmuri Wahyu
Published: August 2024

Dalam konteks digitalisasi perdagangan yang meningkat, perusahaan memerlukan sistem informasi yang kuat untuk meningkatkan pemasaran. Toko Tani Indonesia Center, yang populer karena beragam penawaran produk dan layanan prima, berupaya meningkatkan kualitas layanan melalui aplikasi marketplace berbasis web. Studi ini bertujuan untuk meningkatkan visibilitas produk, memfasilitasi akses pengguna, dan meningkatkan efisiensi transaksi. Penelitian sebelumnya menyoroti kekurangan fitur di marketplace yang ada, mendorong integrasi fungsi tambahan seperti riwayat transaksi, pelaporan penjualan dengan grafik, pilihan metode pembayaran, dan fitur obrolan WhatsApp dalam aplikasi baru. Metode Pengembangan Aplikasi Cepat (RAD) digunakan, melibatkan tahapan identifikasi pengguna, perencanaan kebutuhan, desain pengguna, pengembangan aplikasi, dan cutover. Hasilnya adalah aplikasi yang berpusat pada pengguna yang selaras dengan tujuan pusat, secara signifikan meningkatkan interaksi pengguna dan hasil penjualan, sehingga menunjukkan efektivitas menggabungkan umpan balik pengguna secara komprehensif dalam pengembangan aplikasi.
Perbedaan Dividen Sebelum dan Selama Masa Pandemik pada Perusahaan yang Terdaftar di Bursa Efek Indonesia
Authors: Winarso Beni Suhendra
Published: August 2024

Fenomena pandemic Covid-19 telah melanda seluruh dunia dan berpengeruh terhadap semua sektor kehidupan. Dalam dunia industri, pandemik ini sangat berpengaruhi terhadap proses operasional perusahaan, akibatnya tidak sedikit perusahaan yang merugi namun tidak sedikit pula perusahaan yang mendulang pundi-pundi emas selama masa pandemik. Penelitian ini berusaha untuk mengkaji perbedaan dividen yang dibayarkan oleh 31 perusahaan terdaftar di Bursa Efek Indonesia selama tahun 2017-2020 yang memenuhi krteria sebelum dan selama masa pandemik. Metode yang digunakan menggunakan paired sample test dengan terlebih dahulu dilakukan pengujian normalitas. Sebanyak. Hasil uji normalitas menunjukkan data berdistribusi tidak normal (signifikansi 0,00 dibawah 0,05, ) sehingga pengujian selanjutnya dilakukan menggunakan analisis non parametrik. Berdasarkan hasil pengujian non-parametrik hasil nilai Asymp. Sig sebesar 0.724, lebih besar dari 0,05, hal ini menunjukkan bahwa tidak terdapat perbedaan secara signifikan antara dividen sebelum dan selama masa pandemic.
Pengaruh Pengetahuan Pajak, Tingkat Pendidikan, dan Pendapatan Terhadap Kepatuhan Wajib Pajak Dalam Membayar Pajak Bumi dan Bangunan (Studi Kasus Kelurahan Hadimulyo Barat, Kecamatan Metro Pusat, Kota Metro)
Authors: Palupi Lutfia Indah , Rusdianto Rusdianto
Published: August 2024

Penelitian ini bertujuan untuk mengetahui pengaruh pengetahuan perpajakan, tingkat pendidikan, dan pendapatan terhadap kepatuhan wajib pajak dalam membayar Pajak Bumi dan Bangunan (PBB). Penelitian ini merupakan penelitian kuantitatif. Penelitian dilakukan di Kelurahan Hadimulyo Barat, Kecamatan Metro Tengah. Sebanyak 95 wajib pajak dijadikan sampel dengan menggunakan metode accidental sampling untuk penentuan sampel. Pengumpulan data menggunakan kuesioner dengan teknik accidental sampling. Data yang terkumpul sebanyak 95 wajib pajak. Hasil penelitian menunjukkan bahwa secara parsial dan simultan variabel pengetahuan perpajakan, tingkat pendidikan, dan pendapatan berpengaruh positif signifikan terhadap kepatuhan wajib pajak dalam membayar Pajak Bumi dan Bangunan di Kelurahan Hadimulyo Barat. Temuan dalam penelitian ini memperkuat teori sebelumnya dan menemukan pentingnya sosialisasi perpajakan untuk meningkatkan kepatuhan wajib pajak dalam membayar pajak.
Pengaruh Literasi Keuangan, Pengetahuan Kewirausahaan, dan Sikap Terhadap Minat Berwirausaha Mahasiswa Akuntansi di Kota Yogyakarta
Authors: Angelika Helvyn , Sumaryanto Sumaryanto
Published: August 2024

Wirausaha adalah salah satu faktor pendukung untuk menentukan kemajuan perekonomian negara. Penelitian ini bertujuan untuk menentukan bukti empiris pengaruh positif literasi keuangan, pengetahuan kewirausahaan, dan sikap terhadap minat berwirausaha mahasiswa Akuntansi di Kota Yogyakarta. Metode peneliian yang digunakan adalah pendekatan kuantitatif. Teknik pemilihan sampel pada penelitian ini adalah purposive sampling terhadap mahasiswa program studi akuntansi di Kota Yogyakarta yang telah menempuh mata kuliah kewirausahaan sebagai objek penelitian. Tenik pengumpulan data menggunakan kuesioner yang disebarkan menggunakan media google form kepada 147 responden. Skala likert digunakan dalam melakukan pengukuran sampel. Teknik analisis yang digunakan adalah regresi linear berganda. Hasil dalam penelitian ini adalah secara parsial pengetahuan dan sikap berpengaruh terhadap minat berwirausaha sedangkan literasi keuangan tidak berpengaruh terhadap minat berwirausaha.
Sikap Kemandirian Remaja Broken Home Dengan Tidak Selalu Mengidealkan Orang Tuanya Di Kelurahan Cilangkap Jakarta Timur
Authors: Prayuda Sandro , Esterillita Mari
Published: August 2024

Penelitian ini membahas mengenai Sikap kemandirian Remaja Broken Home Dengan Tidak Selalu Mengidealkan Orang Tuanya Di Kelurahan Cilangkap Jakarta Timur. Penelitian ini menggunakan metode kualitatif hasil penelitian dituliskan secara deskriptif. Teknik pengumpulan data berupa wawancara, observasi dan studi dokumentasi. Hasil dari penelitian ini ialah diketahui jika para remaja dengan latar belakang broken home di Kelurahan Cilangkap, Jakarta Timur sudah tidak menganggap orang tua sebagai sosok yang selamanya benar dalam mengambil sikap, serta sudah mampu untuk mulai melepas ketergantungannya kepada orang tua dan mempunyai sikap tanggung jawab
Classic and molecular cytogenetic findings in leukemia patients from the Western part of Romania
Authors:   Department of Genetics, Genomic Medicine Centre, Victor Babeş University of Medicine and Pharmacy, Timişoara, Romania, Popa Cristina Annemari , Andreescu Nicoleta Ioana ,   Department of Genetics, Genomic Medicine Centre, Victor Babeş University of Medicine and Pharmacy, Timişoara, Romania, Arghirescu Teodora Smaranda ,   Department of Pediatrics, Victor Babeş University of Medicine and Pharmacy, Timişoara, Romania, Petrescu Carmen Angela Maria ,   Department of Pediatrics, Victor Babeş University of Medicine and Pharmacy, Timişoara, Romania, Jincă Cristian Marius ,   Department of Pediatrics, Victor Babeş University of Medicine and Pharmacy, Timişoara, Romania, Huţ Emil Florin ,   Department of Surgery 1, Victor Babeş University of Medicine and Pharmacy, Timişoara, Romania, Drăgoi Răzvan Gabriel ,   Department of Medical Rehabilitation, Victor Babeş University of Medicine and Pharmacy, Timişoara, Romania, Puenea George ,   Department of Medical Rehabilitation, Victor Babeş University of Medicine and Pharmacy, Timişoara, Romania, Popa Daniel ,   Department of Medical Rehabilitation, Victor Babeş University of Medicine and Pharmacy, Timişoara, Romania
Published: August 2024

Acute lymphoblastic leukemia (ALL) is the most common type of leukemia in childhood and rare in adults, while acute myeloid leukemia (AML) is less common in children and more common in older adults. The aim of the study was to present our experience for the diagnostic of leukemia by using the classic and molecular cytogenetic methods. The study was conducted between 2009 and 2019 within the Classic and Molecular Genetic Laboratory of the Oncohematology Department from the Louis Ţurcanu Emergency Hospital for Children, Timişoara, Romania. The study group included 337 children and adults, evaluated between 2009 and 2019. By using the conventional and molecular cytogenetic technique, the cytogenetic anomalies found were 35 numerical chromosomal abnormalities, 10 (9;22)(q34;q11) [four ALL, one AML, five chronic myeloid leukemia (CML)] translocations, nine (15;17)(q24;q21) translocations, three (14;14)(q11;q32) translocations, two (4;11)(q21;q23) translocations, one (1;14)(p32;q11) translocation, one (7;14)(qter;q11) translocation, one (8;21)(q22;q22) translocation, one (9;14)(p12;q32) translocation, seven rearrangements of the MLL gene and two rearrangements of the core-binding factor subunit beta/myosin heavy chain 11 (CBFB/MYH11) gene. The use of conventional and molecular cytogenetic analysis is one of the most important prognostic indicators in acute leukemia patients, allowing the identification of biologically distinct subtypes of disease and selection of appropriate treatment approaches.
The particularities of connective fibers from the wall of varicose veins extirpated by cryostripping
Authors:   Department of Surgery I, Faculty of Medicine, Victor Babeş University of Medicine and Pharmacy, Timişoara, Romania, Părău Andrei Florin , Ceauşu Amalia Raluca ,   Department of Microscopic Morphology/Histology, Angiogenesis Research Center, Victor Babeş University of Medicine and Pharmacy, Timişoara, Romania, Gaje Nela Puşa ,   Department of Microscopic Morphology/Histology, Angiogenesis Research Center, Victor Babeş University of Medicine and Pharmacy, Timişoara, Romania, Olariu Sorin ,   Department of Surgery I, Faculty of Medicine, Victor Babeş University of Medicine and Pharmacy, Timişoara, Romania, Raica Marius ,   Department of Microscopic Morphology/Histology, Angiogenesis Research Center, Victor Babeş University of Medicine and Pharmacy, Timişoara, Romania
Published: August 2024

Introduction: The varicose vein affects more than 30% of the general population. Significantly increased rates were noticed in women and older population. From the histopathological point of view, venous arterialization, smooth muscle cell hypertrophy, and hyperplasia are the main changes noticed in varicose vein disease. Some of the main therapeutic methods used in the management of varicose disease are injection sclerotherapy, conservative, surgical, saphenous vein inversion and removal, high saphenous ligation, ambulatory phlebectomy, transilluminated powered phlebectomy, endovascular management, cryostripping. Aim: The aim of this study was to evaluate the morphology of connective fibers from the wall of the varicose veins extirpated by cryostripping. Patients, Materials and Methods: The study included 109 samples taken by cryostripping method. Hematoxylin–Eosin, Masson’s trichrome, Silver and Orcein staining were applied. The assessment of fibers was made according to score values between 0 and 3. Results: It was found no major structural differences in terms of alterations of collagen fibers induced by the applied surgical procedure. It was noticed duplications and multiplications of the internal elastic lamina, as diffuse and nodular forms. Depletion of elastic fibers at the media was a lesion identified in most of the specimens. The depletion of reticulin fibers correlates with the accumulation of collagen fibers, which partially or completely replace the network in the media and intima. No correlation was found between changes in the reticulin network and the time between prelevation and buffered formalin fixation, the maximum time investigated being five days. Conclusions: The Orcein staining in the venous vessel evaluation panel may be a useful investigation.
Modifications of the articular eminence inclination in association with the loss of occlusal support in the molar area. A cone-beam computed tomography study
Authors:   Department of Oral Rehabilitation, Faculty of Dentistry, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, Vîrlan Maria Justina Roxana , Nimigean Victor ,   Department of Anatomy, Faculty of Dentistry, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, Păun Diana Loreta ,   Department of Endocrinology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, Bisoc Adriana ,   Department of Prosthodontics, Faculty of Dentistry, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, Nimigean Vanda Roxana ,   Department of Oral Rehabilitation, Faculty of Dentistry, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Published: August 2024

The articular eminence (AE) is part of the temporal component of the temporomandibular joint (TMJ). The inclination of the AE (AEI) has an important role in TMJ biodynamics, influencing the path of movement of the disc–condyle complex. Although AEI values might change due to tooth loss, little is known about what effect could have the loss of occlusal support in the molar area on AE morphology. AEI was measured on cone-beam computed tomography (CBCT) images of 41 patients (82 TMJs) with or without occlusal support in the molar region. The patients included in this study were divided into four groups: (1) patients with maintained occlusal support in the molar areas on both sides (right and left side) (MM); (2) patients with loss of occlusal support in the molar areas on both sides (right and left side) (LL); (3) patients with loss of occlusal support in the molar area only on the right side, but with maintained occlusal support on the left molar area (LM); (4) patients with loss of occlusal support in the molar area only on the left side, but with maintained occlusal support in the right molar area (ML). AEI values were higher in the TMJs on the side with maintained occlusal support in the molar area (M) than the AEI values measured in TMJs from the side with loss of occlusal support in the molar area (L). AEI values on the right side were higher in the MM patients in comparison to the AEI values on the right side of LL patients. The loss of occlusal support in the molar areas changes the mandibular biodynamics, which might be reflected in the morphological changes at the AE level, where it might cause flattening of the articular slope predominantly on the right side.
Synchronous laryngeal cancer
Authors:   Department of Otorhinolaryngology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania, Ciolofan Mircea Sorin , Anghelina Florin ,   Department of Otorhinolaryngology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania, Vlăescu Alexandru Nicolae ,   Department of Otorhinolaryngology, Dr. Vlăescu Central Polyclinic, Craiova, Romania, Mitroi Mihaela Roxana ,   Department of Otorhinolaryngology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania, Căpitănescu Alina Nicoleta ,   Department of Otorhinolaryngology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania, Ioniţă Elena ,   Department of Otorhinolaryngology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania, Ioniţă Iulică ,   Department of Otorhinolaryngology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania, Ionovici Nina ,   Department of Occupational Medicine, University of Medicine and Pharmacy of Craiova, Romania, Vrînceanu Daniela ,   Department of ENT, Bucharest Emergency University Hospital, Bucharest, Romania; Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Published: August 2024

Multiple primary cancers are usually defined as primary malignant tumors of different histological origins in one person. Synchronous cancers are defined as two or more primary cancers diagnosed in the same patient at the same time or within six months after identifying the first tumor, and those cancers that develop at more than a six-month interval are termed as metachronous multiple primary cancers. Our study comprised of a patient with synchronous laryngeal cancer with double localizations. The case was solved through surgical excision of the tumors. Histopathological and immunohistochemistry examinations revealed synchronous laryngeal cancer. Laryngeal cancer should usually be managed through surgical resection, followed by oncological treatment.
The Existence of A Court Decision With Legal Force Remains in the Process of Registering Land Ownership for the First Time
Authors:   Master of Notary Program at Warmadewa University, Lestari Ni Kadek Budiani , Astara I Wayan Wesna ,   Lecturer, Faculty of Law, Warmadewa University, Wijaya I Ketut Kasta Arya ,   Lecturer, Faculty of Law, Warmadewa University
Published: August 2024

This research aims to analyze the position of court decisions that have permanent legal force in the certificate issuance process and the mechanism for issuing land ownership certificates based on court decisions that have permanent legal force. This research is normative research which places law as a building system of norms. The approaches used by the author are the Legislative Approach and the Legal Concept Analysis Approach. The research results show that the court decision can be a strong basis for changing or updating land ownership status in land registration records. In issuing a certificate of ownership of land, the application is submitted and the Badung Regency Land Office officer carries out a field inspection. A certificate is issued if the documents are complete which can also be seen from the absence of any notes in the land book.
Voices from within: Employee Perspectives in the Leading Insurance Company in Cagayan de Oro City
Authors:   Research Coordinator, City College of El Salvador, Poblacion City, El Salvador City Alumnus, Capitol University, M. Jala Dr. Jolou Vincent , T. Gaid Joshua ,   Faculty, University of Science and Technology of Southern Philippines-Claveria Campus, Poblacion, Claveria, Misamis Oriental
Published: August 2024

Since human people are an organization's most treasured asset, it is pivotal to learn how they can contribute to the organization efficiently, effectively and productively. This has been a tremendous challenge on the HR manager to evaluate actions and procedures that will progress the organization's efficacy. The aim of this qualitative study is to offer a wide-ranging notion of how human resource managers can enhance procedures to advance organizational performance in the leading insurance firm in Cagayan de Oro City. The study used a qualitative research design, concentrated on the transcendental phenomenological design of Husserl. Transcendental phenomenology (TPh), is a philosophical method to qualitative research design that pursues to comprehend human experience, it was established with noteworthy input from Husserl (Moustakas, 1994). Transcendental phenomenology is grounded on the principle that all previous assumptions (epoche) must be set away in order to see incidences through clear manifestations. By having this, it permits the factual implication of the phenomena to appear naturally alongside and within their exceptionality (Moustakas, 1994). Fifteen (15) individual participants from the insurance industry were involved in the study. In addition, semi-structured interview was created and conducted for triangulation purposes. After collecting relevant data from participant answers, a Thematic Approach was utilized to commence data analysis using Husserl's Phenomenological research design. The results showed that the factors influence the adoption of Strategic Human Resource Management Practices were competitive pressure, leadership and management and financial capability of the organization. Moreover, the participants indicated that the type of commitment that they have in their organization were continuance commitment, affective commitment and normative commitment. Furthermore, the participants gave answer on the influence of effective Strategic Human Resource Management practices in their organization which were employee involvement, employee retention and better organizational performance.
Potential for utilizing Socioeconomic Registration Data to improve targeting of Ministry of Manpower’s Training and Business Assistance Program
Authors: Putra Riski Raisa
Published: August 2024

This policy paper explores the potential for utilizing Registrasi Sosial Ekonom (Regsosek - Socioeconomic Data Registration) to improve the targeting of training and business assistance programs managed by Kementerian Ketenagakerjaan (Kemnaker – Ministry of Manpower) in Indonesia. Indonesia’s National Long-Term Development Plan (RPJPN 2005-2025) aims to create a developed, self-reliant, just, and democratic society. The paper identifies key issues in the implementation of Kemnaker's programs, including Tenaga Kerja Mandiri (TKM - Self-Employed Workers Program) and Pelatihan Berbasis Kompetensi (PBK - Competency Based Training). These issues include inaccurate targeting, lack of inclusivity, and disparities in the geographical distribution of beneficiaries. Data from Regsosek reveals critical gaps in program participation, business ownership, and inclusivity, particularly for marginalized groups such as people with disabilities and women. Moreover, there are significant disparities in program access, with a higher concentration of benefits accruing to wealthier individuals, indicating the need for more effective targeting mechanisms.By leveraging the comprehensive socioeconomic data provided by Regsosek, Kemnaker can develop targeted solutions that more effectively address the unique needs of different demographic groups, ensure equitable resource allocation, and ultimately improve the overall impact of its training and business assistance programs. The paper underlines the importance of data-driven policies in achieving sustainable economic growth and social equity. It points to the critical role of accurate data in informed decision-making, efficient resource allocation, and continuous program improvement. The integration of Regsosek data is presented as a core strategy for enhancing the precision and effectiveness of government interventions aimed at fostering economic independence and improving the livelihoods of Indonesia’s diverse population. By addressing these challenges and implementing the recommended strategies, Indonesia can move closer to its vision of a prosperous, equitable, and inclusive society.
Emerging Artificial Intelligence In Therapeutic Agreements With A Medicolegal Approach
Authors: Dewantara Reka , Pandansari Rekyan
Published: August 2024

Introduction: Medical services use artificial intelligence for operating to help and even transform the healthcare system. AI innovators have developed tools to improve clinical care processes, advance medical research, and increase efficiency in medical services.Purposes of the Research:  The purpose of this article is to analyse the legal validity of therapeutic agreements using AI in medical field.Methods of the Research: The research method used is a normative juridical research type with an analytical approach.Results of the Research: The results show that medical services are complex and closely related systems, and always contain risks, so they must be carried out with great care. Legal provisions governing the use of AI in therapeutic agreements with a medicolegal approach must be able to evaluate and ensure the safety and accuracy of medical decisions made by AI "thinking algorithms".
A meta-analysis of genome-wide association studies to identify candidate genes for feed efficiency traits in pigs
Authors:   , Silva Maria Rita Gonçalves da
Published: August 2024

The pig production industry is an activity of great importance for the economic and social scenarios of the Brazilian and world markets. The growing prominence of feed efficiency traits in production systems, due to their impact on production costs and the environment, has increased the importance given to these traits in animal breeding programs. Genome wide association studies (GWAS) have emerged as an important methodology for assessing the genetic background of complex traits, contributing to a better biological understanding of the trait under study. In this context, this study was carried out with the main objective of identifying and validating candidate genes associated with feed conversion ratio (FCR) and residual feed intake (RFI) through a systematic review and meta-analysis of GWAS in pigs. The systematic review was conducted to compile the studies that would make up the database. For the meta-analysis, information on the significant markers, including associated p-values and number of observations, was extracted from each article. The METAL software was used to implement the meta- analysis. After the meta-analysis, Bonferroni correction was applied considering an alpha of 0.05 to establish statistically significant associations for the genome-wide significance level, by dividing alpha by the number of SNPs tested in the meta-analysis. The significant SNPs in the meta-analysis were used to identify candidate genes. An enrichment analysis was conducted using the Database for Annotation, Visualization, and Integrated Discovery (DAVID). The results of the systematic review revealed 13 studies, of which 10 evaluated FCR and 6 evaluated RFI, identifying a total of 160 markers for FCR and 96 for RFI. After the meta-analysis, 145 and 90 markers were significantly associated with FCR and RFI, respectively. The gene annotation process resulted in 105 and 114 genes for FCR and RFI, respectively. The enrichment analysis for FCR resulted in 16 significant gene ontology (GO) terms, while 6 terms were identified for RFI. The MED18, PHACTR4, ABCC2, TRHDE, FRS2, FAR2 and FIS1 genes stand out as strong candidates for FCR, and the ADGRL2, ASGR1, ASGR2 and MAN2B1 genes for RFI. Keywords: Feed conversion ratio; Residual feed intake, GWAS.
Educação ambiental: cidadania e o manejo humanitário de animais domésticos
Authors:   , Martins Thamires Sousa
Published: August 2024

Esta pesquisa discute o tema educação ambiental no manejo humanitário de animais domésticos na educação básica, conforme a legislação vigente. Teve como objetivo promover a conscientização e o acesso dos professores da educação básica às principais legislações referentes à causa animal e ofertar sugestões para implementá- las no cotidiano escolar de forma interdisciplinar e cidadã. A opção metodológica foi a revisão bibliográfica, recorrendo-se, principalmente, à análise documental das normas jurídicas brasileiras (federais, do estado de Minas Gerais e do Município de São Gotardo-MG), tratados internacionais, documentos escolares e reportagens digitais aplicáveis à Educação Ambiental, Cidadania e Proteção Animal. O método utilizado foi o exploratório. Dentre as principais inferências, identificou-se que a causa animal é um fator de saúde pública e cidadania e que a escola, por meio das práticas docentes reflexivas, exerce um papel imprescindível na transformação da sociedade ao fomentar os estudantes para o exercício de uma cidadania participativa e crítica. Porém, os textos e a amostra analisada indicam que possivelmente é insuficiente a adesão das escolas com relação a valorização da temática. Palavras-chave: Educação Ambiental; Cidadania; Proteção Animal; Animais Domésticos; Cães e Gatos.
Caderno de lâmina digital do módulo II e III da medicina do UniFOA no programa Microsoft™ OneNote©
Authors: Simas Portes Debora , Diniz Pinto Bravo Filho Jose , Fernandes Portes Eduardo , Souza Portes Walter , Alexandre Villani Gantus Michel
Published: August 2024

Com o desenvolvimento tecnológico, a necessidade de acoplar a tecnologia ao ensino se torna cada vez mais evidente. Atualmente, pesquisas evidenciam os benefícios de mesclar o estudo tradicional com meios digitais de ensino, havendo, assim, a modalidade hibrida de ensino. Com base em tais pesquisas e, com o intuito de criar um ambiente de aprendizagem digital de estudo híbrido, o atlas digital de histologia foi criado na plataforma do Microsoft™ OneNote© com informações das aulas práticas da disciplina em conjunto das respectivas imagens das lâminas fotografadas por uma máquina digital acoplada ao microscópio Opticam 0400S do laboratório morfofuncional do UniFOA, no tamanho de 1920x1080 pixels em imagens digitais de 24 bit em aumentos de 4X, 10X e 40X. Resultando, assim, em um total de 67 imagens do módulo II e 144 imagens do módulo III. Posteriormente, as imagens foram editadas através de um programa de edição de imagens para a criação de legendas das estruturas destacadas em cada lâmina. As imagens foram inseridas no programa OneNote para uma organização simples e fácil. Além disso, o conteúdo pode ser disponibilizado offline com a possibilidade de o estudante fazer edições e anotações no material. Assim, o projeto pretende beneficiar docentes e discentes a terem uma aprendizagem mais fácil e interessante da disciplina de histologia.
O Que Você Precisa Saber Sobre Transtornos Alimentares e Não Aprendeu Na Faculdade
Authors: Valentim Vale Lara , Damato Bemfeito Barroso Laura , Coutinho de Melo e Cruz Maria Júlia , José de Paula da Silva Willian , De Faria Nicolau Orlando Joelma , Moreira de Oliveira Jussara , Schächter Guidoreni Angela
Published: August 2024

Os transtornos alimentares são um tipo de adoecimento psíquico que traz consequências tanto físicas quanto mentais, sendo a sua maior prevalência entre os adolescentes e jovens, constituindo-se em um grave problema de saúde pública. Além disso seu tratamento necessita de profissionais qualificados e que saibam trabalhar em um contexto interprofissional, algo que se mostra extremamente desafiador. Diante disso, este artigo tem como objetivo analisar a formação dos estudantes universitários na área da saúde em relação aos transtornos alimentares, buscando entender a raiz do problema que leva os profissionais de saúde a não estarem preparados para tratar os portadores desses transtornos. Para este estudo, foram analisadas a matriz curricular de X instituições de ensino superior no estado do Rio de Janeiro, tanto privadas como públicas e que oferecem pelo menos duas graduações na área da saúde. Além disso, o estudo envolveu a criação de gráficos e revisão da literatura existente, explorando também a importância da abordagem interdisciplinar no tema.
Entrevista a: PhD. Daniela Célleri La responsabilidad del Estado en la protección y asistencia a personas en situación de movilidad humana
Authors: Cifuentes Ruiz Danny Gilberto , Mendoza Escalante Pablo Ricardo
Published: August 2024

Daniela Célleri, es investigadora asociada en el Departamento de Sociología de la Universidad Leibniz Hannover-Alemania, donde obtuvo su PhD. en Sociología y se encuentra cursando su posdoctorado. Es Máster en Ciencias Sociales y Especialista en estudios Interdisciplinarios de Género y Transformación Social. Licenciada en Ciencias Sociales y Socióloga por la Pontiﬁca Universidad Católica del Ecuador. Es directora del Departamento de relaciones internacionales del Distrito Metropolitano del cantón Quito y profesora investigadora del Instituto de Altos Estudios Nacionales-Ecuador. Cuenta con diversas publicaciones en las áreas de investigación: migraciones internacionales, procesos de formación del Estadonación en América Latina, desigualdad social e interseccionalidad, etnicidad y ciudadanía, discriminación y xenofobia. Actualmente investiga sobre la situación y el aporte de inmigrantes en Ecuador.
Fue coordinadora del Proyecto de Investigación: “Situación laboral y aporte económico de los inmigrantes en la actividad comercial en la ciudad de Quito”. Investigadora y miembro del grupo de Investigaciones: Globalización y Migraciones internacionales, Departamento de Sociología y Estudios de Género de la Facultad Latinoamericana de Ciencias Sociales (FLACSO-sede Ecuador). Coordinadora de la Red de Investigaciones sobre América Latina. Etnicidad, Pertenencia y Ciudadanía. Universidades de Hannover, Munster, Colonia, Bonn y Bielefeld, sede-Hannover. esponsable de la línea sobre migraciones internacionales y ciudadanía.
From Outcasts to Believers: Cults, Religions, and Social Perception
Authors: Kugel Reese
Published: August 2024

Emergent faiths often materialize as modest congregations harboring unorthodox beliefs perceived as aberrant by the larger society. Initially marked with the pejorative label of "cult," these groups become consigned to the margins of society, thereby impeding their prospect of integration into the mainstream. Nevertheless, if these communities persist in their commitment to disseminating and upholding their doctrines despite persecution, the passage of time can contribute to their expansion, solidifying their place within a broader religious landscape. Hence, distinguishing between a large cult and a small religion is an exercise in semantics, as the former can be identified as an incipient stage of the latter’s awaiting societal acceptance to achieve theological metamorphosis.
Synergistic CRISPR/Cas9 Gene Editing and CAR T-cell Therapy for FLT3-Mutated in AML
Authors: Lee Derrick
Published: August 2024

Acute Myeloid Leukemia (AML) with FLT3 (FMS-like Tyrosine Kinase 3) mutations poses a significant challenge in oncology. This paper explores the potential of a combined treatment approach involving CRISPR/Cas9 gene editing and CAR T-cell therapy. CRISPR/Cas9 technology can precisely target and correct the FLT3 gene mutation responsible for AML proliferation. Simultaneously, CAR T-cell therapy harnesses the immune system to target FLT3-mutated AML cells using engineered T cells. While promising, these approaches come with challenges, such as off-target effects for CRISPR/Cas9 and complications like cytokine release syndrome for CAR T-cell therapy. Nevertheless, they offer a groundbreaking paradigm shift in AML treatment, potentially providing more effective and personalized therapies for patients with FLT3 mutations. Further research and clinical trials are essential to fully realize their potential and address associated hurdles. This combination therapy offers hope for improving outcomes in AML patients with FLT3 mutations, representing a significant advancement in precision oncology.
Movie Review Sentiment Analysis: Supervised Learning versus Large Language Model
Authors: Kochut Natalia
Published: August 2024

Sentiment analysis is frequently used to derive insights from natural language. Examples include analysis of textual data to measure brand perception, social media trends, or customer opinion about products. This paper evaluates the performance of three supervised machine learning methods and compares them with the next-generation large language model (LLM), which recently gained popularity with the release of OpenAI ChatGPT. Specifically, we explore the application of Decision Tree, Random Forest, and Support Vector Machine classifiers to a representative sample of 100K movie reviews collected by a well-known website, IMDb.com. Reviews are tagged with numeric ratings, allowing the formulation of a supervised learning problem and exploring the ability to differentiate sentiment between strongly opinionated positive and negative reviews and also, a more challenging problem of differentiating between weakly opinionated positive and negative reviews. Models are tuned to optimize recall and precision in this application, achieving an accuracy score of 0.89 for strong reviews and 0.63 for weak reviews. We then compare the results with ChatGPT, without specialized training, which reaches a perfect accuracy score of 1.00 for strongly opinionated reviews and 0.75 for weakly opinionated reviews, concluding that it outperforms supervised learning approaches but is also imperfect in distinguishing more subtle sentiment in weakly opinionated reviews.
A Reconciliation with Reality and Self-preservation
Authors: Li Jasmine-Sixian , Massand Nancy
Published: August 2024

ABSTRACT
The untimely loss of a loved one is an excruciating ordeal. Renowned Victorian Scottish writer George MacDonald was obliged to face the recurring early deaths of family members all his lifetime. Drawing from the background of Victorian literature and his working experience in church, he forges a reconciliation with reality and realizes his self-preservation through religion. His masterpiece, At the Back of the North Wind, is the reflection of his life sufferings, inner world, and way of reconciliation with reality. By examining the characterization of Diamond and North Wind, two leading characters in the book, and the employment of his unique literary technique, this article aims to reveal his motivation in portraying the protagonist of the book—Diamond, a poor little boy living in London, and conclude MacDonald’s means of self-preservation, i.e., interpretation of early death: those who pass away at a young age are angels from heaven. After fulfilling their earthly missions, they return to a better realm they inherently belong to—Heaven. Hence, earthly life is only a fragment of human beings’ existence. MacDonald’s coming to terms with bereavement while facing death holds practical significance today, especially for the people suffering from the loss of loved ones during the COVID-19 pandemic.
A jellyfish inspired soft robot powered by cable-driven actuation
Authors: Wee Andrew
Published: August 2024

Jellyfish’s natural propulsion abilities with a soft body has often served as an inspiration for many soft robots due to their size and efficiency, with many robots being based on the ephyra larva stage of a jellyfish. However, most previous jellyfish-inspired robots were constructed of costly actuation systems, as well as being based on the ephyra larva stage rather than an adult jellyfish. To address these issues, a jellyfish-like soft robot was made with 4 cable-driven actuators which were attached to a dome-shaped soft material, mimicking that of the jellyfish. A mechanism using a servo powered the cable-driven actuators, allowing the dome-shaped cavity to contract its bell uniformly. When actuated, the mechanism expels a jet of fluids from the bell, leading to a positive thrust. The result was empirically measured by collecting video data on the robot's performance underwater.
Application of Machine Learning in Prediction of Lithofacies from Well Logs
Authors: Tian Yuxiang , Renaud Alfred , Goldsztein Guillermo
Published: August 2024

As humanity’s reliance on mineral resources continuously grows, new technologies need to be implemented in the mining industry to fulfill this demand. A method of using well logging data to predict rock types in the surrounding area using a multiclass classification neural network is discussed as a potential way to increase efficiency. The model achieved an accuracy rate much higher than would be possible through guessing, 70% as compared to 11%, demonstrating the effectiveness of such technology. Potential ways this model can be applied and improved were also discussed.
Global Refugee Crisis
Authors: Park Ethan
Published: August 2024

This essay explores the often-ignored historical intersections of forced migration and disability. This intersectional approach directs attention to understudied dimensions of how crossing inequalities of race, class, national origin, and ability can shape the experiences of subordinate groups in various ways. Disabled refugees and asylum seekers are the most economically and socially disadvantaged members of society. This displaced population is at heightened risk for abuse, exploitation, and violence. Through the conceptual frameworks of human rights, disability studies, and critical refugee studies, this paper looks the United Nations 1951 Convention Relating to the Status of Refugees and the 1981 International Year of the Disabled Person and their impact on contemporary policies toward refugees. By analyzing these historical policies, we can gleam insight into ways for improving resettlement policies and practices for disabled refugees in the contemporary moment.
The Transition to Clean Energy and the Role of Building Envelope Efficiency
Authors: Hua Alex , Teichert Kurt
Published: August 2024

The electrification of building systems and the improvement of their envelopes must work in tandem to achieve a truly energy efficient and sustainable outcome. Many jurisdictions, including Boston, MA, and Acton, MA, have already released climate action plans, detailing many steps that can be taken to decarbonize. These plans have many specific strategies when it comes to buildings, from incentivizing building improvements on private property to retrofitting municipal buildings. Building electrification includes many aspects, from the electrification of household appliances like stoves to the conversion of traditional heating and cooling systems to heat pumps; an electrification roadmap by Acton lists many specifics when it comes to the electrification of its municipal buildings. The improvement of envelope, encompassing aspects of a building such as its insulation, air sealing, windows, moisture control, and ventilation system, is an aspect of sustainability that is arguably more important than the pure electrification of systems. Envelope improvements will improve heat pump efficiency at colder temperatures, and will result in significant energy use and cost reductions.
Circadian and Sleep-Wake Dysfunctions of the Hypothalamus in Alzheimer’s Disease Progression
Authors: Kovalchuk Angelina , Eckhardt Joanna
Published: August 2024

Alzheimer’s disease (AD) is a disorder that causes degeneration of brain cells, cognitive decline, and memory loss. AD is characterized by both the accumulation of tau proteins and the amyloid plaques, which inhibit cell function. Cognitive symptoms are considered manifestations of late-stage AD, though other manifestations such as sleep alterations occur long before these symptoms. Moreover, specific subcortical areas of the brain are affected very early on in AD progression, even before cognitive structures such as the hippocampus. One notable region is the hypothalamus, which regulates circadian rhythms, sleep-wake structure, and other metabolic signals. The hypothalamus is significant in AD progression due to its protective qualities and influence on disease development. This paper investigates the regulation of circadian and sleep-wake cycles within the hypothalamus and how desynchronization may contribute to AD pathogenesis in preclinical and early stages of the disease. Because the hypothalamus is a complex and varied structure, other processes of the hypothalamus are also discussed due to their influence on the sleep-wake cycle. Circadian rhythms also vary among different populations, potentially affecting AD onset. Understanding the influence of circadian and sleep-wake cycles on early AD pathology can provide insight into new interventions and therapeutics preceding later stages of the disease.
Synergizing Convolutional Neural Networks and Drug Similarity Estimation for Improved Drug-Drug Interaction Prediction
Authors: Kim Ryeogyung , Kim Hyehyang
Published: August 2024

Drug-drug interactions can cause adverse effects and impact patient safety. Traditionally, the prediction of DDIs has been labor intensive. However, these approaches have certain limitations in terms of scalability, convergence of different drug combinations, and capturing complex interactions. The potential combinations increase as the number of approved drugs increases; this results in the need for efficient methods. This research aims to utilize artificial intelligence and machine learning techniques to develop a method that accurately detects potential DDIs. The proposed idea allows for greater accuracy and automation in predicting DDI, reducing the time and cost required. The proposed method takes two drug formulas as input and employs a Drug Feature Extractor to extract their features. These features are then represented in feature maps, which are used when calculating a similarity score between input drugs and other drugs in the data set, and to predict potential DDIs. The model combines a drug similarity calculator and DDI predictor, enabling the system to process data in a “human-like” method; aiding in predicting interactions for newly developed drugs. The proposed model achieved state-of-art performance with an accuracy of 88.9%. The results demonstrate the efficacy of the proposed method in predicting potential drug interactions.
Mechanisms of bone degradation and prevention factors
Authors: Mora David , Kethar Jothsna , Appavu Rajagopal
Published: August 2024

This research paper thoroughly investigates bone development, spanning embryonic differentiation into osteoblasts and osteoclasts, culminating in the ossification of the cartilaginous template. Postnatally, growth entails longitudinal expansion and appositional growth through the periosteum. Integral for maintaining strength and structure, bone remodeling achieves equilibrium between formation and resorption. Hormones and genetics wield substantial influence, encompassing growth hormones, sex hormones, and transcription factors. The research scrutinizes age-related bone loss, osteoporosis, and the impact of diseases and lifestyle on bone health. Prevention strategies against degradation take center stage, with particular emphasis on nutrition, including the role of calcium and vitamin D. A balanced diet rich in nutrients conducive to bone health is paramount. Exercise is pivotal, particularly weight-bearing and resistance training, stimulating remodeling and fortifying density. Furthermore, the study underscores the significance of smoking cessation and alcohol moderation for sustaining bone health, given their deleterious impact on bone density. The consideration of personalized medical treatments is imperative. The paper highlights the need for interventions tailored to individual requirements and risk factors, encompassing pharmacological treatments and therapies that curtail bone loss while enhancing integrity. This research also offers a comprehensive overview of bone development, the interplay of hormones and genetics, and the repercussions of diseases and lifestyle choices. Strategies for averting degradation, ranging from nutrition and exercise to smoking cessation, alcohol moderation, and personalized medical approaches, are underscored. In conclusion, the synthesis of these factors creates a holistic approach to preserving bone health.