bluuebunny/crossref_metadata_2025 huggingface dataset:
La red clientelar del príncipe de Santo Buono, virrey del Perú, más allá de su séquito. Estudio a partir de una sátira contra la corrupción
Authors: Andújar Castillo Francisco
Published: December 2021

A partir de una sátira política, La comedia del no puede ser, escrita en forma de obra teatral, no para ser representada sino para criticar la tarea de gobierno y al círculo de personas que rodeaban al príncipe de Santo Buono, virrey del Perú entre 1716 y 1719, se estudian en esta aportación dos elementos esenciales de su mandato. En primer lugar, frente a los trabajos clásicos que suelen ocuparse tan solo al séquito que acompañaba desde España a los virreyes, analizamos la red clientelar que rodeó al virrey, formada por actores sociales que residían en Lima y que pertenecían a la Audiencia y al Tribunal Mayor de Cuentas. En segundo término, cotejando el juicio de residencia de Santo Buono con las críticas vertidas en esta sátira teatral, se estudian las prácticas vinculadas a la corrupción que llevó a cabo durante su etapa de gobierno. El estudio de ambos elementos, red clientelar local y dinámicas de corrupción, se aborda de forma interrelacionada.
Aproximación a la producción alfarera en los sitios Alamito durante los primeros siglos d.C. (Noroeste argentino)
Authors: Pereyra Domingorena Lucas
Published: December 2021

Esta investigación procura entender la producción alfarera en los sitios Alamito (Noroeste argentino), habitados durante los primeros siglos d.C. Conocer esta manufactura artesanal es adentrarse en las dinámicas sociales de estos grupos humanos que se caracterizaron por una particular forma de construir, distribuir en el paisaje y abandonar sus viviendas. Se seleccionaron 55 tiestos —representan la variabilidad estilística-morfológica de la muestra estudiada— y fueron sometidos al análisis petrográfico de sus pastas cerámicas. La metodología utilizada incluye el estudio de la matriz arcillosa, la clasificación de las inclusiones (tipo, tamaño y formas) y la descripción de las cavidades. Las regularidades y particularidades registradas en los datos han permitido detectar seis grupos de pastas, que fueron comparados con modos de pastas de áreas cercanas. Este trabajo inició el análisis de las relaciones entre la cerámica Alamito y otras producciones cerámicas del Noroeste argentino durante el Período Formativo.
Aporte al conocimiento de la diversidad poblacional en El Carmen y la banda sur del Río Negro, Norpatagonia (1779-1852)
Authors: Del Valle Moldes Beatriz , Entraigas Jorge Raúl
Published: December 2021

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El mundo en 2022: diez temas que marcarán la agenda internacional
Authors:   Investigador sénior, CIDOB (coordinador y editor), Soler i Lecha Eduard
Published: December 2021

2022 es un año para revaluar los límites de la desigualdad, de las medidas restrictivas, de los planes de estímulo, de las tensiones geopolíticas o de la desconfianza en las instituciones. La recuperación económica y anímica será desigual y estará condicionada a sobresaltos en la rivalidad entre grandes potencias, las subidas de precios y la superación plena de la pandemia. El mundo no tiene un problema de diagnóstico. Se reconoce la necesidad y urgencia de las transiciones socioeconómicas, tecnológicas y climáticas en curso. El debate se centra en saber qué tipo de liderazgo está mejor preparado o goza de mayor legitimidad para pilotar los cambios, cómo transitar este proceso con los menores costes sociales posibles y dónde está el umbral de una posible irreversibilidad. Este es un año donde los liderazgos internacionales se reexaminarán a través de elecciones clave como las de Francia, Brasil, Hungría, las midterm en EEUU, o el XX Congreso Nacional del Partido Comunista de China. ¿Qué tipo de ideas, personas y modelos gozarán de mayor apoyo y legitimidad para transitar hacia el mundo pospandémico?
EARLY FETAL HYDROPIC CHANGES ARE ASSOCIATED WITH MODERATE DILATATION OF THE BRAIN VENTRICULAR SYSTEM: A CLUE TO A POSSIBLE LINK BETWEEN CERVICAL LYMPHATIC ENGORGEMENT AND VENTRICULAR DILATATION?
Authors: Paladini D , Donarini G , Conti A , Costanza De Angelis L , Witte MH , Genesio R , Bernas M , Bellini T , Boccardo F , Ramenghi LA , Bellini C
Published: December 2021

The aim of this study is to assess whether early cervical lymphatic obstruction is associated with a sonographically detectable dilatation of the ventricular system in the 1st trimester of pregnancy. In particular, the objective is to assess whether fetuses with non-immune hydrops fetalis (NIHF), cystic hygroma, or enlarged nuchal translucency (NT) have a greater atrial width/biparietal diameter (AW/BPD) ratio than normal at time of the combined first trimester screening scan. This retrospective study included 96 first trimester fetuses (33 normal and 63 with various degree of cervical lymphatic engorgement). Inclusion criteria were CRL in the 45-84 mm range and availability of one or more three-dimensional volume datasets of the fetal head, acquired from the BPD plane. Each three-dimensional volume dataset was opened and multiplanar correlation employed to align the three orthogonal planes. The ratio between the atrial width and the BPD (AW/BPD ratio) was used to evaluate the possible presence of increased amount of cerebrospinal fluid. Abnormal cases were placed into 4 categories: 1)enlarged non-septated NT 2.5-3.9 mm, no hydrops; 2) grossly enlarged non-septated NT/ edema >3.9 mm; 3) cystic hygroma and/or NIHF; 4) major anomalies with NT <2.5 mm. Presence of dilatation of the latero-cervical jugular lymphatic sacs, karyotype and presence of congenital anomalies were also recorded. The One-way ANOVA test was used to compare means. Intra- and inter-observer variability were also assessed. The AW/BPD ratio was found to be significantly higher in fetuses with grossly enlarged NT/nuchal edema and NIHF/septated cystic hygroma than in normal (p <0.05 and p <0.01, respectively). Also, the AW/BPD ratio was significantly higher in NIHF/septated cystic hygroma than in enlarged NT 2.5-3.9 mm (p <0.05). In case of enlarged NT (2.5-3.9 mm), the AW/BPD ratio is significantly higher in presence of JLS (p <0.01). At the end of the first trimester, presence of cervical lymphatic engorgement, in terms of grossly enlarged NT, nuchaledema, septated cystic hygroma, and NIHF, is statistically associated with a moderate dilatation of the ventricular system. Of note, among fetuses with moderately enlarged NT, those with evidence of dilatation of the JLS show a statistically significant increase in the AW/BPD ratio.
PERCUTANEOUS FLUOROSCOPICALLY-GUIDED TRANSCERVICAL RETROGRADE ACCESS FACILITATES SUCCESSFUL THORACIC DUCT EMBOLIZATION AFTER FAILED ANTEGRADE TRANSABDOMINAL ACCESS
Authors: Bundy JJ , Chick JFB , Jiao A , Cline MR , Srinivasa RN , Khayat M , Gnannt R , Johnson EJ , Gemmete JJ , Monroe EJ
Published: December 2021

The purpose of this study was to demonstrate the feasibility of percutaneous fluoroscopically-guided transcervical retrograde access into the thoracic duct following unsuccessful transabdominal cisterna chyli cannulation to perform thoracic duct embolization for the treatment of chylothorax. Five patients, including three (60%) women and two (40%) men, with median age of 62 years, underwent percutaneous transcervical thoracic duct access and embolization after failed transabdominal cisterna chyli cannulation for the treatment of chylothorax. In all patients, fluoroscopically-guided percutaneous transcervical retrograde access into the distal thoracic duct was achieved using a 21-gauge needle and an 0.018-inch wire. Following advancement of a microcatheter, retrograde lymphangiography was performed to identify the location of thoracic duct injury. A combination of 2:1 ethiodized oil to cyanoacrylate mixtures, platinum microcoils, or stent-grafts were used to treat the chylous leaks. Technical successes, procedure durations, fluoroscopy times, blood losses, immediate adverse events, clinical successes, and follow-up durations were recorded. Technical success was defined as cannulation of the distal thoracic duct using a transcervical approach followed by treatment of the thoracic duct injury. Adverse events were classified according to the Society of Interventional Radiology guidelines. Clinical success was defined as resolution of the presenting chylothorax. Percutaneous transcervical retrograde thoracic duct access and treatment was technically successful in all patients (n=5). Median procedure duration was 173 minutes (range: 136-347 minutes) with a median fluoroscopy time of 94.7 minutes (range: 47-125 minutes). Median blood loss was 10 mL (range: 5-20 mL). No minor or major adverse occurred. Clinical success was achieved in all patients (n=5). Median follow-up was 372 days (range:67-661 days). Percutaneous fluoroscopically-guided transcervical retrograde thoracic duct access is an effective and safe method to perform thoracic duct embolization following unsuccessful transabdominal cisterna chyli cannulation for the treatment of chylothorax.
THE EFFICACY OF INTERMITTENT PNEUMATIC COMPRESSION AS A SUBSTITUTE FOR MANUAL LYMPHATIC DRAINAGE IN COMPLETE DECONGESTIVE THERAPY IN THE TREATMENT OF BREAST CANCER RELATED LYMPHEDEMA
Authors: Sanal-Toprak C , Ozsoy-Unubol T , Bahar-Ozdemir Y , Akyuz G
Published: December 2021

The aim of this study is to evaluate the efficacy of intermittent pneumatic compression (IPC) as a substitute for manual lymphatic drainage (MLD) in complete decongestive therapy (CDT) for treatment of advanced stages of breast cancer-related lymphedema. In this randomized, single-blind, controlled study, 46 patients with breast cancer-related lymphedema were divided into 2 groups. Both MLD with compression bandage (CB) group (n=24) and IPC with CB group (n=22) received treatment 3 days a week for 5 weeks. Home exercise program was also given to all patients. At the end of the 5th week, patients were treated with a daily 23-hour compression garment and home exercise routines. Assessments were taken at baseline, the fifth week, and the third month. Arm circumference was measured at 5 different areas, shoulder range of motion (ROM) was evaluated with a goniometer, pain, and tightness, and heaviness sensations were assessed with visual analog scale. Both groups had similar demographic and clinical characteristics (p < 0.05). There were no significant differences between groups and both groups showed significant improvement (p < 0.05) in the five measurement levels of the arm circumference at the fifth week and third month. Similarly, shoulder ROM, pain, tightness, and heaviness sensations improved in both groups (p < 0.05). Both MLD and IPC as a component of CDT were found successful at 5 weeks and 3 months without superiority to each other.
ISL NEWS
Authors: New ISL
Published: December 2021

ISL CONSENSUS 2020 DOCUMENT UPDATE
A discussion will take place at the next International Congress of Lymphology (September 2019) concerning updates to the ISL Consensus Document on the diagnosis and treatment of peripheral lymphedema. Please send any comments or suggestions for changes, deletions, additions, or clarifications to the Central Office for inclusion of items for discussion.
A HISTORICAL ACCOUNT OF THE ROLE OF EXERCISE IN THE PREVENTION AND TREATMENT OF CANCER-RELATED LYMPHEDEMA
Authors: Johansson K , Hayes S
Published: December 2021

In the absence of guidance from scientific evidence, a range of lymphedema prevention and management, guidelines were developed by relevant organizations around the world. These became publicly available, promoted and endorsed, particularly to women with breast cancer. The recommendations advised avoidance of any activity that could overload or restrict the lymphatic system and need for caution when participating in specific physical activities. However, over the past 20 years evidence has accumulated which has significantly challenged the safety of these recommendations, in particular for those with cancer. There now exists consistent and compelling evidence in support of exercise following a diagnosis of cancer. Participating in exercise during and following cancer treatment improves function and quality of life, reduces treatment-related morbidity, and may improve survival. Further, exercise, including resistance exercise at moderate or high load, is considered safe for those at risk- or with lymphedema. That is, exercise has not been shown to cause or worsen cancer-related lymphedema. This article provides a historical account of the advice given to patients in the prevention and management of lymphedema and how this advice has evolved.
PHYSIOTHERAPY AND REHABILITATION APPLICATIONS IN LIPEDEMA MANAGEMENT: A LITERATURE REVIEW
Authors: Esmer M , Schingale FJ , Unal D , Yazıcı MV , Güzel NA
Published: December 2021

Lipedema is a chronic and progressive disease of adipose tissue caused by abnormal fat accumulation in subcutaneous tissue. Although there is no known cure for lipedema, possible complications can be prevented with conservative and surgical treatments. One of the conservative treatment options is physiotherapy and rehabilitation (PR). When the literature is examined, few studies focusing on the efficacy of PR were found for this patient group. The purpose of this review is to provide a better understanding of the effectiveness of PR applications by compiling existing studies. A bibliographic PubMed search was performed for published studies regarding PR in lipedema management in June 2019 including the last 58 years (1951-2019). Articles were chosen by reading the abstracts and subsequently data were analyzed by reading the entire text through full-text resources. A total of 15 studies met inclusion criteria. Results document how lipedema patients are benefited by PR and the effectiveness of different types of PR programs. The current review also showed that complex decongestive physiotherapy, gait training, hydrotherapy, aerobic exercise, and resistance exercise training each have value in the management of lipedema. The effects of PR for the treatment of lipedema are variable among studies, although overall PR seems to be effective in lipedema management. Although physiotherapy applications have a potentially important role in the management of lipedema, they should be used in combination with other treatment modalities. More studies with higher quality are needed to fully demonstrate the effect and efficacy of PR in lipedema patients.
BONE DEVELOPMENT AND FRACTURE HEALING IS NORMAL IN MICE THAT HAVE A DEFECT IN THE DEVELOPMENT OF THE LYMPHATIC SYSTEM
Authors: McCarter AL , Khalid A , Yi Y , Monroy M , Zhao H , Rios JJ , Dellinger MT
Published: December 2021

Ectopic lymphatics form in bone and promote bone destruction in diseases such as Gorham-Stout disease, generalized lymphatic anomaly, and kaposiform lymphangiomatosis. However, the role lymphatics serve in normal bone development and repair is poorly understood. The objective of this study was to characterize bone development and fracture healing in mice that have a defect in the development of the lymphatic vasculature. We found that bones in wild-type adult mice and mouse embryos did not have lymphatics. We also found that bone development was normal in Vegfr3Chy/Chy embryos. These mice do not have lymphatics and die shortly after birth. To determine whether lymphatics serve a role in postnatal bone development and fracture healing, we analyzed bones from Vegfr3wt/Chy mice. These mice are viable and have fewer lymphatics than wild-type mice. We found that postnatal bone development and fracture healing was normal in Vegfr3wt/Chy mice. Taken together, our results suggest that lymphatics do not play a major role in normal bone development or repair.
IN MEMORIAM
Authors: Szuba A
Published: December 2021

PROFESSOR WALDEMAR LECH OLSZEWSKI, PhD, MDSeptember 3, 1931 - November 8, 2020
COMPARISON OF COMPLETE DECONGESTIVE THERAPY AND KINESIOLOGY TAPING FOR UNILATERAL UPPER LIMB BREAST CANCER-RELATED LYMPHEDEMA: A RANDOMIZED CONTROLLED TRIAL
Authors: Basoglu C. , Sindel D. , Corum M. , Oral A.
Published: December 2021

We designed a study to compare effects of complete decongestive therapy (CDT) and kinesiology taping (KT) (with exercise and skin care) on limb circumference, lymphedema volume, grip strength, functional status, and quality of life in patients with unilateral breast cancer-related lymphedema (BCRL). Forty patients with unilateral stage 2 BCRL were randomized to either the CDT group (n=20) or the KT group (n=20). Patients in the CDT group underwent 30-min manual lymphatic drainage (MLD) and multi-layer, short-stretch bandaging once a week for four weeks. Patients in the KT group underwent taping once a week for four weeks. In addition, all patients were informed about skin care and given an exercise program throughout the treatment. Upper extremity circumference and volume differences as primary outcomes and grip strength, Quick-Disabilities of the Arm, Shoulder and Hand (Q-DASH), and Functional Assessment of Cancer Therapy-Breast (FACT-B) scores as secondary outcomes were assessed initially, after treatment (4 weeks), and at the 1st month follow-up. Limb circumference and volume differences were significantly reduced in the CDT group after the 4-week treatment compared with the KT group (p=0.012 and p=0.015, respectively), but there was no difference between the groups in the 1st month follow-up (p>0.05). There was no difference between the groups in terms of grip strength, Q-DASH, and FACT-B scores after treatment and at the 1st month follow-up (p>0.05). Our results show that both KT and CDT were found to significantly reduce limb volume and circumference individually at 4-weeks and the one-month follow-up in patients with BCRL and that CDT significantly reduced both limb volume and circumference compared to KT at the 4-week time point, but not at the follow-up. Further randomized controlled trials with patients at different stages of BCRL are needed to confirm and expand these results.
Dewan Penyunting
Authors: Poros Admin
Published: December 2021

Jurnal Poros Vol 17 No 1 Mei 2021
Pan Tadeusz Adama Mickiewicza: „stara” – „nowa” lektura
Authors: Gajak-Toczek Małgorzata
Published: December 2021

In the article „Pan Tadeusz” by Adam Mickiewicz: „old” – „new” reading, the author presented the contextual reading of the epic at school through the prism of the works of Czesław Miłosz (metaphysical and epaphysical reading) and Tomasz Różycki (postmodern epic). The adopted perspective allows us to show the timelessness of the works of Czesław Miłosz (metaphysical and epaphysical reading) and Tomasz Różycki (postmodern epic). The adopted perspective allows us to show the timelessness of the work of a romantic artist, the value of narration as a story about Poland and Poles, as well a story about an individual’s fate and its search for a universal meaning of one’s own existenc.
O „polskim” zwyczaju całowania upadłej kruszyny chleba… – z powodu wiersza Cypriana K. Norwida Moja piosnka II
Authors: Bakuła Kordian
Published: December 2021

The author aims to gain knowledge about the custom, its origin and about ourselves, Poles, in order to change the thinking and teaching about the subject of the article. Methods of research procedure: collection, description, interpretation of literary, ethnographic, dictionary material of the past and present: C.K. Norwid’s poem My Song II, a description of the custom by Z. Gloger, other ethnographic descriptions from the nineteenth century and early twentieth century, interviews of students, studies of the attitude of Poles to food. Is kissing a fallen crumb really a Polish custom? It was assimilated rightly from the work of Erasmus of Rotterdam On civility in children (De civilitate morum puerilium); has a literary origin, not a folk background. Today, few Poles practice this custom.
Kompetencje tekstotwórcze uczniów klas pierwszych szkół ponadgimnazjalnych… i ponadpodstawowych – próba porównania
Authors: Trysińska Magdalena
Published: December 2021

The article presents the results of the study of students’ language competences who attend the first secondary school classes. In 2019, as a result of the education reform, two groups of students started their education in the first grades: junior high school graduates and eight-grade primary school graduates. Pre-secondary education in the case of students leaving primary school lasted a year shorter. Both groups took the exam at the end of lower junior high school or elementary school, respectively, and studied according to a different core curriculum.

During the study, it was assumed that thanks to the education that lasted a year longer and was based on a different core curriculum, lower secondary school students should achieve better results in terms of creating an argumentative text and in terms of selected language skills. Both groups of students wrote the same test to confirm or reject the thesis.

The results of the study showed that both groups of students achieved comparable results. In some areas, younger students have even outranked junior high school students. At the same time, it turned out that the lower stage of education was completed by students with very different competences. Both among junior high school and primary school students there are very good and very weak students, while in the group of junior high school students there is a large percentage of very weak students. This may prove that for many students three years of lower secondary school were a waste of time, and the last two years of primary school were enough to master the tested skills.
Refleksje nad pożądanymi kierunkami zmian… w szkolnym kształceniu polonistycznym (głos w dyskusji)
Authors: Fiszbak Jolanta
Published: December 2021

The author describes desirable paths of changes in Polish language school education. Base for the analysis is the research conducted in 2017 on students’ attitude towards Polish language as a subject, as well as students’ works created during the distance learning in 2020. 
According to the author, any changes in the curriculum should be preceded by research conducted on students in order to determine their needs and skills. Addressing changes to unspecified target is the main reason for ill-success of the reforms which were introduced during the past 20 years. Polish language teaching in schools of each level should be more focused on enhancing students’ linguistic skills. The changes should also include the sphere of literature, culture, and media knowledge. The author points to the fact that the reform should involve also teachers-to-be and the way they are prepared for teaching, as well as further education of Polish language teachers.
Sütteki A1-A2 β-Kazeinin Özellikleri Ve İnsan Sağlığına Etkileri
Authors: Yaman Fırıncıoğlu Sema , Kılıç Hatice Nur
Published: December 2021

Despite positive effects on nutrition, it has been reported that milk causes allergic reactions and many health problems. Allergic reaction to milk is called lactose intolerance, but it is estimated that this is not caused by lactose, but by the β -casein structure of milk, which varies depending on animal species. Although there are many fractions of β-casein in the structure of milk, especially A1 and A2 casein attract attention. A1 β -casein causes many health problems because it plays a role in the formation of the bioactive opioid peptide β-casomorphin-7 (β-CM-7). These health problems are allergic reactions, weakening of the immune system and slowing down of the gastro-intestinal system and some systemic diseases (cardiovascular disease, type 1 diabetes, autism, schizophrenia). The underdevelopment of gastro-intestinal system, especially in newborns, causes us to encounter these health problems more frequently. For this reason, the consumption of milk containing A1 β-casein, especially cow’s milk from culture breeds, is not recommended. Since BKM-7 (β-casomorphin-7) formed by A1 β-casein cannot occur in A2 β-casein, these health problems cannot be expected to be observed. However, A2 β-casein causes DPP4 (dipeptidyl peptidase 4) enzymes to be regulated in the body and a non-opioid effect is observed. It is recommended to consume goat’s milk and dairy products containing A2 β-casein in newborns, people with celiac disease and stomach disorders. Despite the lack of studies on the subject of A1 and A2 β-casein and the ongoing discussions, in this review, the importance and differences of A1 and A2 β-caseins in cow and goat milk were discussed and their effects on human health.
Damızlık Bıldırcın Rasyonlarına Portakal ve Limon Kabuğu Esansiyel Yağları ve Karışımlarının İlavesinin Performans, Yumurta Kalitesi ve Kuluçka Parametrelerine Etkisi
Authors: Sevim Behlül , Gökmen Seyit Ahmet , Curabay Barışcan , Cufadar Yusuf , Bahtiyarca Yılmaz
Published: December 2021

The aim of this study was to determine the effects of adding orange peel (PKY), lemon peel essential oils (LKY) and PKY+LKY (respectively 300, 300, 150+150 mg/kg) to laying quail diets on performance, egg internal and external quality parameters and hatchability parameters. The eight-week trial was conducted in 20 subgroups, with 4 treatment groups and 5 replications for each treatment, and a total of 120 Japanese quails at 10 weeks of age were randomly distributed, with 6 quails (4 females, 2 males) in each subgroup. Feed intake with the addition of LKY to the diet, egg production and egg mass with the addition of PKY + LKY decreased significantly compared to the control group, and the eggshell breaking resistance with the addition of LKY and PKY + LKY increased significantly compared to the control group. However, the addition of LKY, PKY and PKY+LKY to the diet did not affect hatchability and reproduction parameters. According to these results, the addition of 300 mg/kg PKY and 300 mg/kg (150+150) PKY+LKY to breeder quail diets had an effect on the increase of eggshell qualityi, although the performance was adversely affected.
El funcionamiento del Sistema Interamericano de Derechos Humanos en tiempos de pandemia: gestión, eficacia y contexto internacional
Authors: Silva González Jorge Luis , Ramos Hernández Clari Neury
Published: December 2021

El artículo tiene como objetivo valorar el funcionamiento del Sistema Interamericano de Derechos Humanos en función de su efectiva observancia, promoción y protección, ante la crisis sanitaria en la región a causa de la pandemia del nuevo Coronavirus. Se sistematizan los referentes histórico-teóricos que fundamentan el sistema, con énfasis en su proceso de fortalecimiento y repercusión en Latinoamérica, se analiza desde el punto de vista jurídico-doctrinal el funcionamiento interno del mismo, así como su gestión y eficacia en la protección de los derechos en el contexto internacional pandémico. Dentro de los resultados obtenidos se encuentra que, a pesar de sus esfuerzos por disminuir el efecto de la pandemia, mediante la Resolución No.1/2020 de su Comisión y la Declaración No.1/2020 de la Corte, hasta la fecha han sido inevitables las violaciones de derechos debido al ascenso de la pobreza y la desigualdad, ante el desplome del rendimiento económico de la región.
A review on chemical constituents of essential oils of Aframomum genus
Authors: Van Hong Thien , Pham Tan Viet , Nguyen Hanh Thi Dieu , Nguyen Ngoc An , Truong Duy H.
Published: December 2021

Aframomum K.Schum is a genus native to Africa belonging to Zingiberaceae. Members of the genus Aframomum are the aromatic and perennial rhizomatous herbs. Many plant parts of Aframomum species contain essential oils, including fruits, seeds, leaves, stems, rhizomes, pods, husks, pericarps, limbos and leaf sheaths. The major constituents of Aframomum plants are mainly composed of sesquiterpene hydrocarbons, oxygenated monoterpenes, oxygenated sesquiterpenes and monoterpene hydrocarbons. The present work provides the comprehensive information regarding the volatile components of various Aframomum species.
FATORES QUE PROPORCIONAM MELHORIA NO PROCESSO COMUNICATIVO SOBRE ACIDENTES DE TRABALHO NAS ORGANIZAÇÕES
Authors: Freitas Lucas Henrique do Nascimento , Casagranda Yasmin Gomes
Published: December 2021

O presente trabalho busca entender como está relacionado o processo comunicativo e as os acidentes de trabalho dentro das organizações, bem como entender quais fatores podem melhorar esta comunicação. A análise foi feita a partir de uma revisão integrativa dos descritores selecionados nas bases de dados Scielo e Capes Periódicos: “Comunicação” e “Indústria”; e posteriormente “Acidentes de Trabalho”. Os resultados apontaram que um sistema de informação e comunicação interno eficiente pode melhoras a análise de dados sobre os acidentes de trabalho. Além disso, o levantamento das incidências pode ser subsídio para um plano de ação para proteção e bem-estar dos trabalhadores. São necessários, ainda, dados oficiais consistentes e o desenvolvimento de métodos de comunicação e investigação que possam ser usados por todas as empresas, independentemente do seu setor de atuação e tamanho.
Military clergy of the 4th Orenburg Army Corps of the Kolchak Army based on the documents of the dean corps of S. V. Kaverznev
Authors: Veber Mikhail
Published: December 2021

This article is dedicated to the history of the Russian Orthodox Church during the revolutionary disturbances of 1917 and the Russian Civil War. The subject of this research is the the history of military clergy of the Kolchak Army. The article introduced into the scientific discourse the report of the dean of the 4th Orenburg Army Corps of the Southern Army of the Armed Forces of Admiral A. V. Kolchak –  archpriest Stefan Vasilyevich Kaverznev on the activity of military clergy of the corps in August – September of 1919. This is a valuable historical source that contains records on staff composition of regimental priests of the 4th Orenburg Army Corps, as well as reveals the engagement of military priests in propaganda activity among the soldiers and officers of the corps. The report of the archpriest S. V. Kaverznev provides valuable information on the history of military operations of the 4th Orenburg Army Corps in summer of 1919, which ended with its defeat and escape to the Turgai Steppe. The article also publishes the formal request of the archpriest S. V. Kaverznev on the emergency situation that took place in the 4th Orenburg Army Corps – desertion of the regimental priest of the 6th Syzran Rifle Regiment Vasily Yaremenko, who joined the Reds in early September of 1919. The author believes that this document testifies to the escalated symptoms that led to decomposition of the Kolchak Army in the autumn of 1919.
Analisis Manajemen Pengelolaan Linen Di Instalasi Laundry Rumah Sakit Permata Hati Duri Kec Mandau Kab Bengkalis Tahun 2020
Authors: Ardrianti Reni , Candra Leon , Wahyudi Arief
Published: December 2021

Rumah sakit dalam memberikan pelayanan kesehatan perlu ditunjang oleh pelayanan non medik, salah satunya instalasi laundry. Survei awal di RS Permata Hati Duri menggambarkan bangunan instalasi laundry Rumah Sakit tidak memenuhi standar serta jumlah linen yang belum mencukupi. Tujuan penelitian ini yaitu untuk menganalisis manajemen pengelolaan linen di laundry RS Permata Hati Duri Kecamatan Mandau Kabupaten Bengkalis Tahun 2020. Penelitian ini merupakan penelitian kualitatif dengan pendekatan deskriptif yaitu secara khusus membuat gambaran berdasakan hasil wawancara dan observasi. Penelitian ini dilakukan di Rumah Sakit Permata Hati selama satu bulan, mulai tanggal 31 April sampai dengan 30 Mei tahun 2020. Informan dalam penelitian ini menggunakan metode purposive sampling (non probability) yaitu kepala ruangan instalasi laundry, kepala bagian K3 RS dan umum, kepala bagian keperawatan, staf laundry, staf keperawatan. Analisis data menggunakan triangulasi data. Hasil penelitian yaitu SDM di instalasi laundry RS Permata Hati terdiri dari 4 orang staf pelaksana dan 1 orang kepala ruangan. Staf belum mendapatkan pelatihan. Sarana peralatan di instalasi laundry RS Permata Hati telah tersedia, namun prasarana seperti ruangan belum sesuai dengan standar serta belum ada sekat pemisah antara tiap kegiatan pengelolaan linen. SPO di instalasi laundry RS Permata Hati telah tersedia, disosialisasikan dan ada di ruangan serta terdapat reward dan punishment bagi petugas yang tidak menjalankan SPO. Namun evaluasi yang dijalankan belum maksimal.Diperlukan penambahan tenaga staf pelaksana di instalasi laundry RS Permata Hati serta pelatihan kepada para staf agar tidak terjadi kendala dalam pengelolaan dan pendistribusian linen.
FAKTOR YANG BERHUBUNGAN DENGAN KELUHAN KELELAHAN MATA PADA PENGGUNA KOMPUTER DI STIKES HANG TUAH PEKANBARU TAHUN 2020
Authors: Hanafi Muhammad Hanafi , Asril Asril , Efendi Ahmad Satria
Published: December 2021

Kelelahan mata adalah gangguan yang dialami mata karena otot-ototnya yang dipaksa bekerja keras terutama saat harus melihat objek dekat dalam jangka waktu lama. Tujuan penelitian ini adalah ntuk mengetahui hubungan antara karakteristik pekerja dan perangkat kerja dengan keluhan kelelahan mata pada pengguna komputer. Penelitian ini merupakan penelitian analitik kuantitatif dengan menggunakan desain studi cross sectional, dengan responden kasus adalah pekerja yang menggunakan komputer di STIKes Hang Tuah Pekanbaru. Jumlah sampel dalam penelitian ini adalah 46 orang. Teknik pengambilan sampel pada kasus adalah non probability sampling. Alat ukur yang di gunakan adalah kuesioner, dan pengukuran. Analisis yang di gunakan adalah univariat dan bivariat dengan uji statistik Chi-square. Hasil penelitian menunjukkan bahwa ada hubungan yang signifikan antara usia (Pvalue=0,024, nilai OR=5,409), durasi penggunaan komputer (Pvalue=0,020, nilai OR=5,143), jarak pandang mata dengan monitor (Pvalue=0,009, nilai OR=6,500) dengan kelulahan kelelahan mata. Hasil penelitian menunjukkan tidak ada hubungan signifikan antara penggunaan anti glare (Pvalue=0,457, nilai OR=1,929) dengan keluhan kelelahan mata. Disarankan kepada pekerja menjaga jarak mata dengan layar monitor, melakukan istirahat mata sekitar 10 menit stiap jam, dan mengatur pencahayaan monitor dalam menggunakan komputer.
Eye fatigue is a disorder experienced by the eye because the muscles are forced to work hard, especially when they have to look at close objects for a long time. The purpose of this study was to determine the relationship between the characteristics of workers and work equipment with complaints of eye fatigue in computer users. This research is a quantitative analytic study using a cross sectional study design, with case respondents being workers who use computers at STIKes Hang Tuah Pekanbaru. The number of samples in this study were 46 people. The sampling technique in this case is non-probability sampling. The measuring instrument used is a questionnaire, and measurement. The analysis used was univariate and bivariate with Chi-square statistical test. The results showed that there was a significant relationship between age (P value = 0.024, OR value = 5,409), duration of computer use (P value = 0.020, OR value = 5.143), distance between eyes and monitor (Pvalue = 0.009, OR value = 6,500) with complaints of eye fatigue. The results showed that there was no significant relationship between the use of anti-glare (P-value = 0.457, OR = 1.929) with complaints of eye fatigue. It is recommended for workers to keep their eyes away from the monitor screen, take an eye break of about 10 minutes every hour, and adjust the lighting of the monitor when using the computer.
ANALISIS BAURAN PEMASARAN DI RUMAH SAKIT PEKANBARU MEDICAL CENTER (PMC) KOTA PEKANBARU TAHUN 2020
Authors: Nurkumala Asih Anggri , Devis Yesica , Abidin Aldiga Rienarti
Published: December 2021

ABSTRAK

Bauran pemasaran merupakan salah satu strategi pemasaran untuk menyampaikan informasi secara luas, memperkenalkan suatu produk barang dan jasa. Bauran pemasaran yang lazim digunakan perumah sakitan indonesia adalah 7P yaitu : produk, harga, tempat, promosi, orang, bukti fisik, dan proses. Tujuan penelitian ini secara umum untuk mengetahui bauran pemasaran di Rumah Sakit Pekanbaru Medical Center (PMC). Penelitian yang digunakan adalah penelitian kualitatif, dilakukan dengan metode wawancara dan observasi kepada 5 informan yaitu manajer humas dan marketing, staf humas dan marketing 1, staf humas dan marketing 2, pengunjung keluarga pasien, masyarakat. Hasil penelitian menyebutkan bahwasannya rumah sakit belum memiliki pelayana MRI  dan rencana kedepannya akan memiliki bedah digestif dan rumah sakit juga memiliki produk unggulan rehabilitasi kesehatan jiwa dan narkoba ditambah lagi klinik bayi tabung. Sedangkan untuk plang petunjuk arah masih belum jelas dan fasilitas khususnya di parkiran motor kurang luas dan belum ada atap atau kanopinya. Disarankan bagi pihak rumah sakit untuk lebih memperhatikan pelayanan MRI dan juga plang petunjuk rumah sakit dan juga lebih menggiat aktifkan promosi Rumah Sakit PMC disegala aspek media sosial dan juga lebih memperhatikan lokasi parkiran agar pengunjung yang datang lebih nyaman.

 

Daftar Pustaka  :  19 (2010-2020)

Kata Kunci    : Bauran Pemasraan, Pemasaran, Rumah Sakit Pekanbaru Medical Center (PMC)
Air drag coefficient of textile-covered elastic cylinders – preliminary aerodynamic studies
Authors: Siegmund Jana , Wendt Ellen , Rothe Stefan , Kyosev Yordan , Hildebrandt Veit , Pfifer Harald , Schubert Sebastian , Schleifenbaum Stefan
Published: December 2021

This paper presents preliminary experimental results on the influence on the aerodynamic drag of a cylinder from the cylinder type (i.e., rigid or soft) and its textile surface. Both a rigid cylinder and a soft-body cylinder, with a gelatin layer, each with five different textile surfaces were measured in the wind tunnel using force measurement technology. The drag coefficient was determined for several Reynolds numbers. The study shows that the elasticity of a cylinder has a significant influence on the drag force and the airflow type. However, the influence of the soft-body cylinder depends on the respective fabric. With the given measurements, no exact statements can yet be made to quantify the influence. This influence must be studied independently and in conjunction with the textile surface in order to gain understanding of the overall system of airflow, textile and elastic body.
Dicoordinate Au(I)–Ethylene Complexes as Hydroamination Catalysts
Authors: Navarro Miquel , Alferez Macarena G. , de Sousa Morgane , Miranda-Pizarro Juan , Campos Jesus
Published: December 2021

A series of gold(I)–ethylene  complexes containing a family of bulky phosphine ligands has been prepared. The use of these sterically congested ligands is crucial to stabilize the gold(I)–ethylene bond and prevent decomposition, boosting up their catalytic performance in the highly underexplored hydroamination of ethylene. The precatalysts bearing the most sterically demanding phosphines showed excellent results reaching full conversion to the hydroaminated products under low ethylene pressure (1 bar). Kinetic analysis together with density functional theory (DFT) calculations revealed that the assistance of a second molecule of the nucleophile as a proton shuttle is preferred even when using an extremely congested cavity-shaped Au(I) complex.
Approaching the Spin-Statistical Limit in Visible-to-UV Photon Upconversion
Authors: Olesund Axel , Johnsson Jessica , Edhborg Fredrik , Ghasemi Shima , Moth-Poulsen Kasper , Albinsson Bo
Published: December 2021

Triplet-triplet annihilation photon upconversion (TTA-UC) is a process in which triplet excitons combine to form emissive singlets, and holds great promise to improve the spectral match in solar energy and biological applications. While high TTA-UC quantum yields has been reported for e.g., red-to-green TTA-UC systems there are only a few examples of visible-to-UV transformations in which the quantum yield reaches 10%. In this study we investigate the performance of six annihilators when paired with the sensitizer 2,3,5,6-tetra(9H-carbazol-9-yl)benzonitrile (4CzBN), a purely organic compound that exhibits thermally activated delayed fluorescence (TADF). We report a record-setting TTA-UC quantum yield of 16.8% (out of a 50% maximum) for 1,4-bis((triisopropylsilyl)ethynyl)naphthalene (TIPS-Naph), demonstrating the first example of a visible-to-UV TTA-UC system approaching the classical spin-statistical limit of 20%. Three other annihilators, of which 2,5-diphenylfuran (PPF) has never been used for TTA-UC previously, also showed impressive performances with TTA-UC quantum yields above 12%. In addition, a new method to determine the rate constant of triplet-triplet annihilation is proposed in which only time-resolved emission measurements are needed, circumventing the need for more challenging transient absorption measurements. The results reported herein represent an important step towards highly efficient visible-to-UV TTA-UC systems which hold great potential for driving high-energy photochemical reactions.
Liquid-liquid phase separated microdomains of an amphiphilic graft copolymer in a surfactant-rich medium
Authors: Castellvi Corrons Xavier , Gummel Jeremie , Smets Johan , Berti Debora
Published: December 2021

The liquid-liquid phase separation (LLPS) of amphiphilic thermoresponsive copolymers can lead to the formation of micron-sized domains, known as simple coacervates. Due to their potential to confine active principles, these copolymer-rich droplets have gained interest as encapsulating agents. Understanding and controlling the conditions inducing this LLPS is therefore essential for applicative purposes and requires thorough fundamental studies on self-coacervation. In this work, we investigate the LLPS of a comb-like graft copolymer (PEG-g-PVAc) consisting of a poly(ethylene glycol) backbone (6 kDa) with 2-3 grafted poly(vinyl acetate) chains, and a PEG/PVAc weight ratio of 40/60. Specifically, we report the effect of various water-soluble additives on its phase separation behavior. Kosmotropes and non-ionic surfactants were found to decrease the phase separation temperature of the copolymer, while chaotropes and, above all, ionic surfactants increased it. We then focus on the phase behavior of PEG-g-PVAc in the presence of sodium citrate and a C14-15 E7 non-ionic surfactant (N45-7), defining the compositional range for the generation of LLPS microdomains at room temperature and monitoring their formation with fluorescence confocal microscopy. Finally, we determine the composition of the microdomains through confocal Raman microscopy, demonstrating the presence of PEG-g-PVAc, N45-7, and water. These results expand our knowledge on polymeric self-coacervation, clarifying the optimal conditions and composition needed to obtain LLPS microdomains with encapsulation potential at room temperature in surfactant-rich formulations.
Engineering multi-functional protein biologics through PAL-mediated hydrazide ligation
Authors: Zhang DingPeng , Wang Zhen , Chen Wei Meng , Pui Sze Min , Hu Side , Lescar Julien , Tam James P. , Liu Chuan-Fa
Published: December 2021

Attributed to the -effects, hydrazides are nucleophilic despite being non-basic. Herein, we report that the hydrazide nucleophiles are effective acyl acceptors in the ligation reactions catalyzed by peptidyl asparaginyl ligases (PALs). Because hydrazides are easily functionalizable, hydrazide ligation is highly versatile. Interestingly, the linkages formed with the hydrazide substrates have varying degrees of liability toward the PAL enzyme, with some being remarkably resistant and thus ensuring nearly irreversible ligation. Using the hydrazide ligation method, we labelled an EGFR-targeting affibody-Fc fusion protein with various functional moieties to generate selective and potent cancer-imaging and therapeutic agents. Irreversible hydrazide ligation also allowed a sequential ligation scheme to be conducted on a protein. Using this scheme, quadruple FITC labels were introduced onto the N- and C-termini of the affibody-Fc protein to yield a bi-specific engager for Car-NK cell therapy. Our work expands the substrate scope of PAL enzymes and further point to their promise as a precision manufacturing tool for multi-functional protein biologics.
Reduced Molecular Flavins as Single-Electron Reductants after Photo-Excitation
Authors: Foja Richard , Walter Alexandra , Jandl Christian , Thyrhaug Erling , Hauer Jürgen , Storch Golo
Published: December 2021

Flavoenzymes mediate a multitude of chemical reactions and are catalytically active both in different oxidation states and in covalent adducts with reagents. The transfer of such reactivity to the organic laboratory using simplified molecular flavins is highly desirable and such applications in (photo-)oxidation reactions are already established. However, molecular flavins have not been used for the reduction of organic substrates yet, although this activity is known and well-studied for DNA photolyase enzymes. We report a catalytic method using reduced, molecular flavins as photo-reductants and γ-terpinene as sacrificial reductant. Additionally, we present our design for air-stable, reduced flavin catalysts, which is based on a conformational bias strategy and circumvents the otherwise rapid reduction of O2 from air. Using our catalytic strategy, we were able to replace super-stoichiometric amounts of the rare-earth reductant SmI2 in a 5-exo-trig cyclization of substituted barbituric acid derivatives. Such flavin-catalyzed reductions are anticipated to be of broad applicability and their straightforward synthesis indicates future use in stereo- as well as site-selective transformations.
Site-selective Amide Functionalization by Catalytic Azoline Engrafting
Authors: Powell Wyatt , Evenson Garrett , Walczak Maciej
Published: December 2021

Amide activation is a challenging transformation due to the stabilizing effect of the amide group. While enzymes can be considered as prototypical systems that have evolved to achieve high selectivity and specificity, small-molecule catalysts that functionalize the amide group may accommodate a much larger selection of substrates but currently re-main scarce. Here, by combining the desired features from both catalytic regimes we designed an artificial cyclodehy-dratase, a catalytic system for site-selective modification of peptides and natural products by engrafting heterocyclic into their scaffolds. The catalytic system features molybdenum(VI) center that was decorated with a sterically congest-ed tripod ligand. The optimized catalyst can introduce azolines into small molecules, natural products, and oligopeptides with high efficiency and minimal waste. We further demonstrate the utility of the new protocol in direct func-tionalization of a single amide group in the presence of up to seven other chemically similar positions, and direct conversion into amines and thioamides. This new mechanistic paradigm may address an unmet need for a general method for selective and sustainable functionalization of peptides and natural products.
Ligand exchange in zirconocene dichloride–diethylzinc bimetallic systems
Authors: Mozgovoj Oleg , Kadikova Rita , Ramazanov Ilfir , Khalilov Leonard , Dzhemilev Usein
Published: December 2021

The reaction between zirconocene dichloride and excess diethylzinc in d-6-benzene solution was studied. It was found that the exchange reaction between Cp2ZrCl2 and Et2Zn is accompanied by the formation of such complexes as bis-(cyclopentadienyl)ethylzirconium chloride (EtZrCp2Cl), a zirconium-organozinc complex, and bis-(cyclopentadienyl)diethylzirconium (Et2ZrCp2). It was also found that as a result of ligand exchange in zirconocene dichloride–diethylzinc bimetallic systems, the zirconium-organozinc complex is formed in minor amounts. An assessment of the thermodynamic stability of the obtained products is given based on the results of DFT analysis. The description of the NMR spectral data of the obtained organozirconium complexes is carried out.
Lo fantástico como género liminal en el cine
Authors: Huapaya Fernanda
Published: December 2021

Una extrapolación de la literatura al cine, con la clasificación que hizo Todorov de lo fantástico, permite analizar las categorías de uno de los géneros que mejor ha sabido reinventarse en el transcurso de los años. Su facilidad de adaptación y su capacidad de coexistencia con otros géneros les ha permitido a cineastas de todo el mundo tomar sus elementos como materia prima para innumerables trabajos, lo cual nos permite entender su vigencia.