bluuebunny/crossref_metadata_2025 huggingface dataset:
CASE HISTORY OF PRIMARY LEIOMYOMA OF LOWER RESPIRATORY TRACT
Authors: Urazovsky N Y , Khabarov Yu A , Khaidukova N B
Published: March 2018

The present report describes a 40-year old female in whom CT showed tumor of the right lung with bronchus compression. VTS showed tumor of the right lung with pericardium involvement but VTS biopsy could not identify the type of tumor. The patient underwent right pneumonectomy with pericardium resection. The diagnosis of a rare lung disease – primary leiomyoma of lower respiratory tract was confirmed only by immunohistochemistry.
CHEYNE-STOKES RESPIRATION DURING SLEEP AS THE MASK OF EXACERBATION OF IHD. DIAGNOSIS AND TREATMENT BY ADAPTIVE SERVOVENTILATION
Authors: Kalinkin A L , Shestopalova I M , Ardashev A V , Bertova O N , Kuzovlev O P
Published: March 2018

The case report of the patient with complaints of recurrent sudden breathlessness at night is presented. The approach of the diagnosis and therapy is introduced. The effectiveness of the treatment of CheyneStokes respiration by adaptive servoventilation has been shown.
SCIENTIFIC AND THEORETICAL VALIDATION OF DEVELOPMENT OF PERSONALIZED ANTI-CANCER CELL PREPARATION ONTHE BASES OF CLINICAL ONCOPROTEOMICS TECHNOLOGY
Authors: Bryukhovetskiy I S , Bryukhovetskiy A S
Published: March 2018

In the article the authors present analysis of current conventional methodological and technological approaches to contemporary therapy of cancer and certain malignant neoplasms. Based upon the revision of available concepts of clinical oncology, the scientific and theoretical validation of novel approaches to the development of innovative technologies of proteomebased regulatory tumor therapy was attempted. The authors defined their original viewpoint on the development of the preparations for personalized therapy of cancer and proposed a new methodology and alternative approach to the malignant tumors therapy when a cancer stem cell becomes the main target of anticancer therapy. The authors showed that proteome of a cancer stem cell is the most stable information structure of a cell and can be perceived as the main therapeutic target.
ENDOSONOGRAPHY MONITORING IN THE DIAGNOSIS OF DISEASESOF HEPATOPANCREATODUODENAL ZONE AND STOMACH
Authors: Morozova T G , Borsukov A V
Published: March 2018

It is estimate of clinical features and prospects of endosonography in 112 patients with disease of stomach: submucosa neolasm (n=42, 37,5%), chronic ulcer (n=11, 9,8%), cancer-ulcer (n=4, 3,6%) and hepatopancreatoduodenal zone: chronic pancreatitis (n=38, 33,9%), pseudotumor pancreatitis (n=9, 8%), pseudocyst (n=4, 3,6%), cancer of pancrease (n=4, 3,6%). During research it has been specified a place of endosonography typical for hepaticpancreaticoduodenal zone and stomach in determining the prevalence of malignant process in stomach and pancreas, as well as with elastography to differentiate further tactics of patients.
REVASCULARISATION IN SUDDEN CARDIAC DEATH RISK REDUCTION
Authors: Yashin S M , Gromyko G A
Published: March 2018

This issue is about risk stratification and ability of risk reduction in patients undergoing revascularization procedures. Appropriate use of implantable cardioverter-defibrillator in this patients is also discussed.
RESONING FOR THE USE OF A CYLINDRICAL CAGE AFTER VENTRAL DECOMPRESSION OF DEGENERATIVE STENOSIS OF LUMBAR SPINE
Authors: Abakirov M Dzhumabekovich , Abdrachmanov R R , Artem’ev A A , Mader A E , Akhpashev A A
Published: March 2018

Successful use in over 10 years of cylindrical titanium cages after anterior decompression for degenerative diseases of the lumbar spine, and the lack of justification for its use, led us to carry out mathematical modeling using finite element methods. For 10 years we have operated on more than 1200 patients with a primary spinal canal stenosis caused by disc herniation, hypertrophy of the elements of the spine, and at reoperation for failed back surgery syndrome.
Cliniсal-biomeсhaniсal basis of intra-artiсular injeсtion therapy in patients with knee osteoarthrosis
Authors: Zagorodniy N V , Karpovich N I , Skvortsov D V , Damaj Ali I , Akhpashev A A
Published: March 2018

In the article authors describe the basic pathogenetic mechanisms of development of osteoarthritis, a modern approach to the treatment of this group of diseases. Outlined the problems of treatment of coxarthrosis, gonarthrosis in elderly patients with the presence of concomitant somatic pathology. The study used a unique method for estimating motion in gait. Held objectification of treatment results in aged patients with knee joint hyaluronic acid.
OPTIMIZATION OF BIOLOGICAL THERAPY IN PATIENTS WITH ULCERATIVE COLITIS (CASE REPORT)
Authors: Knyazev O V , Kagramanova A V , Fadeeva N A , Kirova M V , Orlova N V , Parfenov A I , Boldyreva O N
Published: March 2018

Now in Russia registered two biological drugs for the treatment of UC is infliximab and golimumab. The largest experience with the use of infliximab (IFX) shows that, despite the high efficiency, in some patients the IBD (20-30%) will develop acquired secondary loss of response to the drug. The development of secondary loss of anti-cytokine therapy is influenced by the following causes - irregular administration of the drug, monotherapy with monoclonal antibodies, initial high levels of TNF-α and low albumin, the presence of antibodies to the drug, activation of opportunistic infections, and changes in pathogenesis of the disease. The appearance at present in the arsenal of gastroenterologists of golimumab (GLM) has expanded the possibilities of treatment of patients with UC in the case of secondary loss of response to therapy with anti-TNF-α or the development of adverse events on IFX. This clinical case shows that after discontinuation IFX, there is a risk of recurrence of the disease, which according to the literature is 50 %. The example also demonstrated that GLM is well tolerated in patients who develop adverse events on IFX in the form of anaphylaxis. This is because GLM are fully human inhibitor of TNF-α. Golimumab is a new, effective inhibitor of TNF-α, which may help to optimize therapy in UC.
CLINICAL OBSERVATION EMPTY THE EXTRAPLEURAL OLEOTHORAX
Authors: Korotkov P B , Levakova A V , Smirnova O P , Tabueva I Yu
Published: March 2018

Reviewed the clinical case of empty extrapleural oleothorax. The data of laboratory study, computed tomography and surgcal tactics are given.
GRAFTS FOR CORONARY SURGERY
Authors: Zotov A S , Anokhin A V , Arinchev R S , Tereshenko V I , Shin A R , Tsvetkov D S
Published: March 2018

Results of surgical treatment of coronary heart disease, both immediate and distant, are directly depend on the consistency of shunts. The variety of factors that determine the good function of the conduit raises a difficult question before the surgeons: what kind of graft should be chosen in every situation? The article presents the analysis of the advantages and disadvantages of various conduits, methods of their application and factors that affect the viability of grafts in the near and in the future.
SURGICAL CLINIC OF FEDERAL SCIENTIFIC CLINICAL CENTER FMBA OF RUSSIA: ON THE EDGE OF THE ACHIEVEMENTS OF MODERN SCIENCE AND PRACTICE
Authors: Panchenkov D N , Ivanov Yu V
Published: March 2018

The article is devoted to the surgical clinic, Federal scientific clinical center FMBA of Russia, its modern level. Presented new surgical techniques successfully implemented over the last 5 years (2011-2015) and widely used in the surgical clinic of Federal scientific clinical center FMBA of Russia. Emphasis is placed on the description of new minimally invasive technologies. Given the ongoing attention of the clinic staff, research and educational work. The results of surgical clinic clearly show that the close and fruitful collaboration between practicing surgeons, the staff and specialists from other medical institutions, is fully justified.
MORPHOLOGICAL AND ULTRASOUND CHARACTERISTICS OF ENDOMETRIUM IN PATIENTS WITH BREAST CANCER AND THE RISK OF SECONDARY TUMORS
Authors: Gerasimov A V , Krasilnikov S E , Kedrova A G , Afonina N S , Nechaeva O E , Maksimenko T A , Kosyi V V
Published: March 2018

The analysis of features of endometrial hyperplasia in patients with breast cancer (BC) receiving adjuvant tamoxifen therapy in the period from 2011 to 2014 inclusive. 196 patients with breast cancer with ultrasound criteria of endometrial hyperplasia were examined. A postoperative histopathologic examination revealed that the lesions were endometrial hyperplasias and with 4,1% malignant findings. Hyperplasia, polyps and endometrial cancer were diagnosed in patients receiving tamoxifen, which allowed a comparison clinicoanamnestic, ultrasound, morphological and genetic characteristics of the endometrium to recover a high risk of developing a second cancer, as well as offer a pathogenic variant of its prevention. The article can be interesting as for obstetrician-gynecologist, watching women after breast cancer treatment, and oncologists, choosing a drug for adjuvant therapy.
MEDICAL CARE TO PATIENTS WITH CARDIOVASCULAR DISEASE IN FEDERAL SCIENTIFIC CLINICAL CENTER
Authors: Chupin A V , Staferov A V , Zotov A S
Published: March 2018

Diseases of the circulatory system are the major social problem worldwide. The prevalence of these diseases, disability, mortality, temporary disablement and the need for specialized medical care contribute to medical and social significance of this pathology, for which our society incurs tangible human and economic losses. According to experts, the number of deaths from CVDs will increase due to the increase of mortality among the male population from 18.1 million in 2010 to 24.2 million in 2030. Mortality rates from CVD in the Russian Federation - one of the highest in the world.
EXPRESSION OF OCT-4, P53, P16 AND KI-67, WITH HPV ASSOCIATED PRECANCER AND CANCER OF THE CERVIX
Authors: Kogan E A , Ts Li Ts , Faizullina N M , Kazachenko A V
Published: March 2018

The pathology of cervical HPV infection is detected by three types of epithelial-mesenchymal spheroidal structures: reparative, neoplastic and cancerous involved in reparation processes and in tumor growth. Cancer spheroids are different from neoplastic not only larger in size but also a tendency to merge, and high expression of p53. Expression of tumor markers p53, p16 and Ki-67 could be used in the early differential diagnosis of precancer and squamous cell carcinoma of the cervix.
PRIMARY INFERTILITY AND FOREIGN BODY (CORPUS ALIENUM) ABDOMINAL CAVITY
Authors: Dobrokhotova Y E , Grishin I I , Ibragimova D M
Published: March 2018

The given clinical example of prolonged bearing of foreign body, leading to infertility. A number of recommendations aimed at the optimization of reference for this group of patients were drawn up.
CLINICAL CASE OF 19-YEARS-OLD PATIENT WITH CONGENITAL ADRENAL CORTEX DYSFUNCTION
Authors: Ascolskaya S I , Tàzitdinov R H , Popov Yu V , Soyustova E L , Okulov A B
Published: March 2018

Congenital adrenal hyperplasia is caused by partial or complete block of enzymatic systems involved in the synthesis of steroid hormones of the adrenal cortex and leading to reduced production of glucocorticoids. Surgical correction is subject to, developing in utero, as a result of changes in hormonal profile, virilization. The article describes the clinical observation of a girl of 19 years, which has not underwent surgery for this disease at the usual term.
DIFFICULTIES OF DIFFERENTIAL DIAGNOSIS BETWEEN ATYPICAL LEIOMYOMA AND LEIOMYOSARCOMA OF THE UTERINE BODY
Authors: Kogan E A , Solomakhina M A , Askolskaya S I , Popov Yu V , Kozachenko A V , Fayzullina N M , Kekeeva T V , Shikeeva A A
Published: March 2018

Leiomyoma of the uterus is a benign hormone-dependent tumors in women.The incidence of LM among gynecological diseases is 25 to 50%, according to different authors. In reproductive-aged women its frequency is about 30%. WHO recommends to allocate leiomyoma, which in russian literature often referred to as a simple or ordinary leiomyoma, and its histologic variants (cellular, mitotic activity, epithelioid, myxoid, atypical leiomyoma and lipoleyomioma etc.).We performed clinical and morphological analysis of atypical uterine leiomyoma in 44-year-old woman. Immunohistochemical study detected positive reaction to smooth muscle actin, dismin, progesterone receptors, N-caldesmon. Adverse reactions to c-kit, ER keratins. Proliferation index by Ki-67 does not exceed 10%. At the molecular genetic research in the studied loci, the microsatellite instability and loss of heterozygosity, characteristic of the LMS, were not revealed.
SPECIAL APPROACHES TO BREAST CANCER HORMONAL THERAPY OF YOUNG PATIENTS
Authors: Kravchenko D N , Parokonnaya A A , Nechushkin M I , Avtomonov D E
Published: March 2018

Breast cancer is the most prevalent female malignancy. When diagnosed at young age (up to 40 years), negative clinical, morphological and prognostic features are noted. A non-randomized retrospective trial (n=500) was performed to evaluate different scenarios of breast cancer hormone therapy in young patients. Ovarian suppression in young patients is shown to statistically improve prognosis. Disease-free survival rate values are observed to decrease in patients without ovarian suppression in comparison with any type of ovarian suppression, especially at a remote follow-up (after 60 months). Menstrual function resumption and no amenorrhea after chemotherapy significantly decrease disease-free survival rate values in young patients.
MODERN TRANSARTERIAL CHEMOEMBOLIZATION AS A STEP TOWARDS THE TREATMENT OF MALIGNANTTUMORS OF THE UTERI AND CERVIX
Authors: Lebedev D P , Kedrova A G , Astakhov D A , Shablovsky O R , Wanke N S
Published: March 2018

Introduction: Advanced cases of carcinomas with parametrial and fornix infiltration often cause massive genital bleeding, with severe anemia, fast deterioration, and a high risk of death for patients. One method of stoped bleeding is transarterial chemoembolization, which has been studied. Methods: Seven women with advanced uterine and cervix cancer or the pelvic locoregional recurrence withgenital massive bleeding were treated using an endovascular therapy (transarterial chemoembolization (TACE) using cisplatin or doxorubicin or gemcitabine). Ware used HepaSphere (Bioshere Medical, France) filled with saturated 50 mg doxorubicin or 500 mg gemcitabine or 50 mg cisplatin. Results: On average, the total operative time for the procedure was 52 minutes. In all cases, the achieved control bleeding. By the 7th day were signs of reduction in tumor size, 1/3 of its original size. The maximum effect on the tumor size was achieved within 14-20 days. In 2 cases, chemoembolization performed twice at an interval of 21 to 28 days, due to a good picture of the ultrasound tumor vascularization. All operations are carried out under the I/V anesthesia and we had no adverse reactions or complications. Conclusions: Arterial chemoembolization dominant vessels tumor is a reliable method of stopping the genital bleeding at any time during of the planned treatment. It is to improve the quality of life of patients. Antitumor efficacy of drug has a lasting effect. The method is applicable as a minimally invasive, effective for treatment of cancer patients.
ZENKER’S DIVERTICULUM: MODERN APPROACHES TO SURGICAL TREATMENT
Authors: Ivanov Yu V , Sazonov D V , Panchenkov D N , Shablovsky O R , Istomin N P
Published: March 2018

The study is devoted to the peculiarities of surgical treatment of Zenker diverticulum. For convenience and for safety we propose the use of intraoperative video endoscopic transillumination of the diverticulum. The method significantly increases the safety of operation, shortens its duration and results to a better cosmetic effect. To avoid relapse, diverticulectomy should be supplemented by cricopharyngeal myotomy.
ON-PUMP BEATING HEART MYOCARDIAL REVASCULARIZATION FOR HIGH RISK PATIENTS
Authors: Zotov A S , Klypa T V , Borisov D V , Ilyin M V
Published: March 2018

107 patients with mean ejection fraction 40,6±7,4% underwent on-pump-beating heart coronary revascularization and associated procedures. There were 76 men and 31 women, with a mean age of 68,9±7,8 years. Five patients required carotid endarterectomy and twelve patients required left ventricular aneurysm repair. 5 patients underwent carotid endarterectomy and 12 patients - left ventricular aneurysm repair. The mean number of graft/patient was 2,9±0,8. Postoperatively occurred the following complications: acute ischemic stroke - 1 (0.9%), acute heart failure - 1 (0.9%), respiratory failure - 2 (1.9%) and bleeding required surgical revision - 1 (0.9%). Hospital mortality rate was 0,9% (1 of the 107 patients). On-pump beating heart technique is a safe and efficient method for coronary artery bypass grafting and associated procedures (carotid endarterectomy, left ventricular aneurysm repair).
INDUSTRIAL MEDICINE: EXPERIENCE AND PROBLEMS
Authors: Ivashova I S , Vanin A V , Moiseenko D A
Published: March 2018

The article discusses the positive experience of the Southern regional medical center of FMBA of Russia in the system of industrial healthcare. Describes the experience of work in selected areas of industrial medicine - diving and marine medicine, the tasks and the experience of the Center of professional pathology, discussed a number of problematic issues.
ANALYSIS OF EARLY POST-OPERATIONAL COMPLICATIONS IN PATIENTS UNDERGOING LAPAROSCOPIC SURGERY FOR HIATAL HERNIA
Authors: Burikov M A , Shoolgin O V , Skazkin I V , Kinyakin A I , Sokirenko I A
Published: March 2018

In order to identify the advantages of the original modification of Nissen fundoplication techniques and identify the safest mash material for prosthetic reinforcement of hiatal closure, was made analysis of early postoperative complications in 121 patients with hiatal hernia.The formation of the non tension fundoplication reduces the level of early postoperative complications. The usage of biological prosthesis has the advantage in comparison with synthetic ones. In general, the usage of mashes significantly increases the severity of the complaints of patients after the intervention, but most of them are within 3-14 days of the postoperative period.
THE RELATIONSHIP OF KIDNEY FUNCTION WITH ARTERIAL WALL CONDITION IN INDIVIDUALS WITHOUT CHRONIC KIDNEY DISEASE AND CARDIOVASCULAR DISEASES
Authors: Pykhtina V S , Strazhesko I D , Tkacheva O N , Sharashkina N V , Vygodin V A , Plokhova E V , Boytsov S A
Published: March 2018

Background: Chronic kidney disease (CKD) is a known risk factor for cardiovascular disease (CVD). However, there is a small information about increased risk of CVD already with a slight decrease in kidney function. Substrate for CVD development is subclinical changes in the arterial wall, which can be accelerated by known risk factorsHypothesis: We have assumed that even an initial impairment of kidney function were capable of adversely affecting on the arterial wall.Objective: To examine the association of kidney function with the condition of the arterial wall in persons without CKD and CVD in different age groups.Materials and methods: The study group included 253 subjects free of known CVD and CKD. The average age of the subjects was 51.5 ± 13.3 g. There were 172 women and 81 men. The group of conditionally “older” (women> 55 years, men> 45 years) was 117 people, conditionally “younger” (women ≤ 55 years, men ≤ 45 years) - 136. 55 subjects had arterial hypertension 1-2 st. All subjects had a glomerular filtration rate (GFR) ≥60 ml / min / 1.73 m2, albuminuria <30 mg /24h. When assessing the condition of the arterial wall, the pulse wave velocity (PWV)> 10 m / s had 93 people, the complex intima-media thickness (CIMT)> 0.9 mm had 42 people, the presence of atherosclerotic plaques (AP) had 106 people, and a decrease in endothelium-dependent vasodilation (EDVD) <10% in 86 people. An elevated urea level> 8.3 mmol / l in the blood was detected in 10 people. Determination of creatinine, urea in the blood serum was carried out by routine methods. Measurement of PWV with the help of applanation tonometry. Measurement of CIMT and determination of AP was carried out by means of duplex scanning of carotid arteries. Measurement of EDVD - using a test with reactive hyperemia.Results: Statistical analysis of the results of this study was carried out using the SAS application statistical software package (StatisticalAnalysisSystem, SAS InstituteInc., USA). In the course of multivariate linear regression analysis, a statistically significant independent association of the urea level with CIMT (β = 0.023, p = 0.023) was detected in the “older” group taking into account the correction for sex, systolic blood pressure level, smoking, body mass index, fasting glucose level and albuminuria. Independent relationships of levels of GFR, creatinine and albuminuria with parameters of the vascular wall were not revealed.Conclusions: The level of urea had a direct independent relationship with CIMT in the older age group, which is more likely due to the ability of urea to enhance oxidative stress. Interrelations of the level of GFR, albuminuria, creatinine with the condition of the arterial wall were not obtained in the study group
CLINICAL ASPECTS OF SLEEP DISORDERS IN PATIENTS WITH PARKINSON’S DISEASE
Authors: Andrienko O A
Published: March 2018

According to the scientific literature of sleep disturbance in patients with Parkinson’s disease meet from 51 to 85 %. In this study, PD patients with sleep disturbances were found in 50.1% (348 of 694 patients) were included in the registry (it surveyed patients with PD, aged from 21 to 90 years with different stages of BP living in different cities and districts of the Rostov region), noted sleep disorders during the disease, as well as to verify the diagnosis of PD. In the future, EEG-somnography were selected 48 patients with BP stage 2 on the Hoehn-Yahr, aged 52 to 71 years, and 50 healthy volunteers aged 49 to 67 years. It is established that in patients with PD stage of sleep you go faster - less time awake, and time of stage 1 non-REM sleep and the stage of paradoxical sleep (PS) in comparison with healthy volunteers. Chronic dyssomnia may occur due to ingestion of antiparkinson medications. Sleep duration decreases, but the psychological need remains the same. Structural changes are observed in sleep are significantly reduced slow-wave stage of sleep, some to a lesser extent, REM-phase and total sleep time.
EXPERIENCE OF REHABILITATION THE ATHLETES AFTER SURGICAL INTERVENTION ON THE ACHILLES TENDON
Authors: Belyakova A M , Sereda A P , Samoilov A S
Published: March 2018

Achilles tendon injury frequency increases. The lack of standardized methods of rehabilitation after surgery on the Achilles tendon leading to increased risk of repeat injury tendon and reduces the possibility return to physical activity. Recovery of function the main task of rehabilitation programs, especially when working with athletes. We have a program of rehabilitation of 147 patients was per- formed after surgery on the Achilles tendon, which began from the first day after the operation and was as much as possible early onset of axial load.
METABOLISM AND CHEMILUMINESCENT ACTIVITY OF NEUTROPHILIC GRANULOCYTES IN PATIENTS WITH DIFFERENT SENSITIVITY TO ACETYLSALICYLIC ACID IN ACUTE CORONARY SYNDROME
Authors: Grinshtein I Yu , Savchenko A A , Grinshtein Yu I , Gvozdev I I
Published: March 2018

Objective: to study the features of the chemiluminescent state and the activity of NAD (P) -depen- dent dehydrogenases in neutrophilic granulocytes of blood in patients with different sensitivity to acetylsalicylic acid (ACA) in acute coronary syndrome (ACS).Materials and methods: The study included 53 patients with ACS. Evaluation of resistance or sensitivity to ASA was performed in vitro by incubating platelet-rich plasma with adenosine diphosphate and ASA to determine the level of aggregation. The state of respiratory explosion of neutrophils was investigated by the method of chemiluminescence. The activity of enzymes in neutrophils was studied by the bioluminescent method.Results of the study: In patients with ACS-resistant ACS, the rate of synthesis of primary and secondary active forms of oxygen was reduced, and the index of luminol-dependent activation of neutrophils was reduced. The intensity of substrate stimulation of glycolysis and oxidation of glucose by the pentose phosphate pathway is increased.Conclusion: With resistance to ASA in patients with ACS, there are abnormalities in the metabolism and functional activity of neutrophils, which is of interest in studying the intercellular relationships of thrombus formation.
Reducing Interprofessional Conflicts in Order to Facilitate Better Rural Care: A Report From a 2016 Rural Surgical Network Invitational Meeting
Authors: Pelletier Hayley
Published: March 2018

An invitational meeting organized by the Centre for Rural Health Research con-vened to facilitate respectful dialogue with general surgeons in British Columbia; the objective was to clearly understand concerns and address questions around rural family physicians with enhanced surgical skills (FPESS). In particular, the meeting focused on interprofessional challenges that hinder the adoption of a network model between general surgeons and FPESS. This report summarizes the findings (n = 5) and recommendations (n = 8) made during the meeting. The meeting underscored the need for more thoughtful discussions to develop interprofessional trust and support between general surgeons and FPESS through an integrated health care system and proper networks.
A case of intra-operative anaphylactic shock in hepatic hydatidosis with inadequate chemotherapy and proximity to hepatic vessels
Authors: Noor Mohamed Shawnas Bahnou , Newton Mario Victor , Govindaraj Sridar , Prakash Clement , Pavithra B. , Padaki P. A. , Jasmine A.
Published: March 2018

Incidence of intraoperative Hydatid anaphylaxis is 0.2-3.3% Reporting of such rare cases is crucial for future reference and study. 52 years old lady presented with hepatic hydatidosis. Computed Tomography showed 2 cystic lesions; one in segment 6, 7 in proximity to right hepatic vein; multiseptated cyst with multiple daughter cysts in segment 4 adjoining the middle hepatic vein with intracystic vessel. No rupture seen. Preoperatively she was prescribed Albendazole 400mg twice-daily for 3months. She was given Hydrocortisone before surgery. 10% povidone iodine mops to prevent intraperitoneal spillage and hypertonic saline used to flush the cyst. One hour after anesthesia when the Segment IV cyst close to middle hepatic vein was punctured she had anaphylactic shock, resuscitated. Marsupialization of both the cysts with omentoplasty and intracystic drains done. She recovered well and discharged with Albendazole for 1 month. Growing cyst produces complex echinococcal antigens, increased cellular immune response, Th2 balanced with Th1; elevated immunoglobulin levels. In dead cysts Th2 responses drop rapidly. Albendazole 10mg/kg for 3 months causes good cyst wall degeneration, less viability of protoscoleces and cyst, less echinococcal antigen production. After the surgery we found that she had stopped albendazole in the preoperative period, which she did not reveal pre-operatively fearing delay in surgery. Inadequate albendazole, close proximity of cysts to vascular structures with high intracystic pressure would have predisposed to develop anaphylactic shock during cyst handling. Preoperative Albendazole can reduce anaphylaxis, morbidity and mortality due to hydatid, making hydatid surgery safer.
Prevalence of pulmonary hypertension in COPD
Authors: Katiyar Vivek , Khare Rajesh Kumar
Published: March 2018

Background: Chronic obstructive pulmonary disease is a leading cause of morbidity and mortality in adults all over the world. Pulmonary hypertension (PH) is a severe disorder defined by a mean pulmonary artery pressure of ≥25 mmHg at rest. Pulmonary hypertension can occur as an isolated disease or as a consequence of a number of underlying diseases and conditions, such as heart failure and chronic obstructive pulmonary disease (COPD). The aim of our study was to study the prevalence of pulmonary hypertension in COPD patients and to highlight the importance of early diagnosis of pulmonary hypertension to prevent further complications.Methods: This was a retrospective observational hospital based study conducted at Integral Institute of Medical Sciences and Research Lucknow U P, during 1st January to 31st December 2017. A total of 210 patients were evaluated for presence of pulmonary hypertension using chest X-ray, electrocardiogram, 2D echocardiography.Results: The present study finding reveals 38.02 % patients of various severity of COPD have findings of pulmonary hypertension, that is similar in prevalence of previous studies.Conclusions: The prevalence of PH in patients with COPD was 38.02%. As PH has an important role in the prognosis of COPD patients, it should be evaluated in as many COPD patients as possible.
Use of feracrylum in tonsillectomy
Authors: D. C. Sathyaki , Roy Mereen Susan , G. Vishnu Kumar , R. Jyothiswarup
Published: March 2018

Background: Haemorrhage is the most common complication which is encountered in tonsillectomy. Various methods have been employed to minimise it. One such method has been employed in this study. The objective of the study was to study the efficacy of feracrylum in reducing post tonsillectomy haemorrhage with that of tranexemic acid.

Methods: 40 patients who underwent tonsillectomy in a tertiary care centre were involved in this study. They were classified into two groups with 20 patients in each group.  

Results: Use of feracrylum reduced the haemorrhage significantly. Only one patient required ligation of vessels.

Conclusions: Use of feracrylum reduces haemorrhage significantly as compared to that of intra venous tranexemic acid.

 
A AVALIAÇÃO EM LARGA ESCALA NOS CENTROS EDUCACIONAIS DE TEMPO INTEGRAL: MAIS TEMPO, MELHORES RESULTADOS?
Authors: Souza Rosana Ramos de , Colares Anselmo Alencar
Published: March 2018

A consolidação do Sistema Nacional de Avaliação da Educação Básica (SAEB), na última década, impulsionou as redes estaduais a criarem sistemas próprios de avaliação. No Amazonas foi criado, em 2008, o Sistema de Avaliação do Desempenho Educacional do Amazonas (SADEAM). Ambos os sistemas (nacional e estadual) apresentam como objetivos a melhoria na qualidade educacional e a concretização de políticas públicas pautadas nos diagnósticos e resultados das avaliações. Ao verificar que os Centros Educacionais de Tempo Integral (CETIs), têm alcançado índices satisfatórios no IDEB, este artigo visa analisar o desempenho do CETI Deputado Gláucio Gonçalves nas avaliações em larga escala. O estudo pautou-se na análise de documentos, tais como o Plano de Gestão e Regimento Geral dos CETIs; a análise de microdados do IDEB e IDEAM e a descrição da avaliação implementada pelo Estado, bem como entrevista com a gestora para identificar as ações geridas no CETI Deputado Gláucio Gonçalves para atingir as metas nas avaliações externas. Constatou-se um aumento contínuo das notas no IDEB e IDEAM dos CETIs. Identifica-se no local pesquisado uma tendência de utilizar este “mais tempo” para intensificar a preparação dos alunos para as avaliações em larga escala. Com isso, não é consenso afirmar que estes resultados sejam traduzidos como qualidade educacional.

Palavras-chave: Avaliação em Larga Escala. Tempo Integral. Qualidade.
EDUCAÇÃO INTEGRAL EM PAUTA: “A ESCOLA DE TEMPO INTEGRAL OU QUE VISE UMA FORMAÇÃO INTEGRAL É UMA POSSIBILIDADE PARA A MELHORIA DO ENSINO NO BRASIL”. UMA ENTREVISTA COM ROMUALDO PORTELA DE OLIVEIRA
Authors: Caetano Camila Arelaro
Published: March 2018

A educação integral tem sido foco de discussões políticas em segmentos diversos no contexto da educação brasileira, com especial destaque para produções acadêmicas que consideram o diálogo profícuo entre as políticas públicas e experiências educativas. Na entrevista apresentada o professor Romualdo Portela de Oliveira atualiza o cenário das políticas em educação integral e aponta para uma perspectiva das possibilidades reais, frente as políticas nacionais, na ampliação das ações em relação a implementação de uma escola de educação integral no Brasil.

Palavras-chave: Educação integral. Educação em tempo integral. Política educacional.
El rol de las humanidades en la formación de los trabajadores sociales
Authors: Arrese  Igor Héctor Óscar
Published: March 2018

En este trabajo intento mostrar la importancia de las Humanidades para la formación de trabajadores sociales. En este contexto, considero las teorías de la justicia, a fin de determinar el rol de la Universidad en la construcción de una sociedad justa. Como consecuencia, planteo la importancia de promover las relaciones de reconocimiento entre los ciudadanos, desde el enfoque de Axel Honneth. A fin de evitar las relaciones de menosprecio, considero que es importante no tratar al otro como un mero objeto, sino más bien ponerse en su lugar. Por eso, considero relevante el enfoque de Martha Nussbaum, basado en el desarrollo de la empatía pormedio de la educación humanística y artística.Nussbaum sostiene que la experiencia estética nos permite ponernos en contacto con nuestro mundo emocional, para luego poder captar la interioridad del otro. Por otro lado, el estudio de la filosofía nos permite reconstruir la posición del otro y mirar el mundo desde el punto de vista del otro. En este contexto, considero la necesidad de desarrollar un modelo de desarrollo humano en la formación de los trabajadores sociales, orientado no sólo al entrenamiento técnico, sino también ampliado al desarrollo de la creatividad y el pensamiento crítico, que son fundamentales para el logro de una ciudadanía plena.
Türkiye’de Keçi Yetiştiriciliği Ekonomisinin Bölgelere Göre Çok Boyutlu Ölçekleme Analizi İle Karşılaştırılması
Authors: Adanacıoğlu Hakan , TAŞKIN Turğay , KANDEMİR Çağrı , KOŞUM Nedim
Published: March 2018

Bu çalışmada;
TÜİK’in istatistiki bölge sınıflandırması esas alınarak Türkiye’deki 12
bölgenin canlı keçi, canlı teke, keçi sütü ve keçi karkas et fiyatlarının
birlikte değerlendirilerek bölgelerin birbirlerine olan benzerlikleri ve
farklılıkları ortaya konulmuştur. Söz konusu fiyat değişkenleri kullanılarak
bölgeler arasındaki ilişkiler çok boyutlu ölçekleme analizi yöntemi ile elde edilmiştir.
Bu çalışmada elde edilen sonuçlara göre, Türkiye’de bazı bölgelerin canlı
hayvan, karkas et ve süt fiyatları açısından diğer bölgelerden önemli derecede ayrıştığı
görülmektedir. Yapılan çok boyutlu ölçekleme analizinde pozitif yüklere göre
değerlendirme yapıldığında, en önemli ayrıştırıcı bölgeler birinci boyutta
İstanbul, ikinci boyutta ise Batı Marmara’dır. Aldığı en yüksek negatif değerle
canlı hayvan, karkas et ve süt fiyatları açısından en farklı bölge birinci
boyutta Kuzeydoğu Anadolu iken, ikinci boyutta Orta Anadolu Bölgesidir. Bu
çalışmada, keçi yetiştiricilerinin eline geçen fiyatlar açısından Türkiye’deki
istatistiki bölgeler arasında önemli farklılıklar olduğu da ortaya konulmuştur.
Bölgeler arasındaki fiyat marjının azaltılması ve keçi yetiştiriciliğinin
ekonomik sürdürülebilirliği açısından özellikle de İstanbul, Batı Marmara,
Kuzeydoğu Anadolu ve Güneydoğu Anadolu gibi genel eğilimden sapma gösteren bazı
bölgelerin incelenmesini gerekli kılmaktadır. Bu kapsamda söz konusu bölgelerde
hem arz hem de talep yönlü olmak üzere kapsamlı araştırmalara ihtiyaç
bulunmaktadır. Bu amaçla yapılacak araştırmalarda keçi yetiştiriciliğini
ekonomik yönden sürdürülebilir hale getirecek ve keçi eti ile sütüne olan
talebi artıracak davranışsal analizlere odaklanılması önerilmektedir.
The Effect of Human Resources Competencies on a Firm Performance: A Marketing Perspective (With Reference to Firms Located in UAE)
Authors: Awad Ashraf
Published: March 2018

Till date numerous theories in the field of marking has recognized both the need for improved marketing skills and the literature which provide in-depth analysis and details about such marketing skills and competencies for the help of marketing managers.For the current work, a questionnaire was served over the managers of 162 companies, constituting 52 percent of industrial firms in Abu Dhabi. A pre-tested questionnaire having details about three prominent dimensions of leadership management, marketing and personal attributes, as measures of company performance were sent to them to analyse and to add to existing stock of knowledge on marketing skills and competency. The questionnaire turnover ratio was 77 percent, which was suitable for statistically significant analysis.The current research has been carried out with aim to find out how much fund multi-national companies (MNCs) should allocate to Human Resource building, also to bring out competencies issues across industries, along with that to develop nexus between employee competencies and firm performance and finally to devise an appropriate mechanisms through which these relationship in companies may operate. Findings of the current work revealed that human resource competencies on the firm performance from marketing perspectives paly its role through different channels namely organizational cultural, communication system, managing changes, knowledge sharing, employees inspiration by leaders, global completion, empowering employees, leadership competency and taking initiatives by employees.It has been observed that performance perception, which is based on manager individual perception and a managerial style, has a negative impact on perceived benefits of creativity negligence factors. Out of nine motivating factors, only five factors were found having statistically significant impact on the competencies of firms in the selected sample of manufacturing and service industries. Analysis shows that management initiatives highlight the fact that not all of them are necessarily successful.
The Nurses’ Role in Providing Comfort During Childbirth Using Ambulation and Hydrotherapy
Authors: Johnson Nicolette , Nokomis Zoë , Stark Mary Ann
Published: March 2018

Providing care and comfort to women during childbirth is an important role. While medical interventions are available, all are associated with potential risks. Using nonpharmacologic means to support the normal process of birth, nurses may reduce the use of medical procedures and their potential complications. The purpose of this article is to discuss the use of two techniques that promote physiologic childbirth, ambulation and hydrotherapy, and the nurses’ role in providing comfort using these techniques in this important life event. Use of these techniques may delay or minimize the use of medical interventions while supporting the normal physiology of labor and birth.
CRONOLOGIA DE AZULEJOS HISTÓRICOS: Danos e Caracterização Química dos Revestimentos das Fachadas do Museu da Abolição no Recife, Pernambuco
Authors: Muniz Eduardo De Freitas , Monteiro Gabriela De Andrade , Lavalle Henry , Souto Maior Paulo Martin , Souza Ravena Barbosa de , Lucena Renata Alves
Published: March 2018

A pesquisa que resultou neste relatório partiu de uma série de fotografias das décadas de 1970-80, do acervo do Iphan em Pernambuco, nas quais se registra a intervenção ocorrida no antigo Sobrado Grande da Madalena como motivo de sua adequação e reforma para abrigar o Museu da Abolição. A partir dessas imagens e de documentos administrativos da instituição indagou-se quais azulejos eram antigos e quais eram mais recentes, pois não se localizou nenhum registro técnico da intervenção nas fachadas dessa edificação. Embora os azulejos mantenham o padrão estético do século XIX as fotografias denotam intervenções nas quais alguns elementos foram substituídos por réplicas. Mapear o estado de conservação, caracterizar quimicamente e identificar quais azulejos são antigos e quais são recentes foram os objetivos principais desta pesquisa. HISTORICAL TILES CHRONOLOGY:  Damage and Chemical Characterization of the Facade Cladding of the Abolition Museum in Recife, Pernambuco ABSTRACTThe research that resulted in this report came from a series of photographs from the 1970s and 1980s, from the Iphan collection in Pernambuco, in which one was registered the intervention in the old Sobrado Grande of Madalena for its adaptation and renovation to the Museum of Abolition. From these images and administrative documents of the institution, we inquired which tiles were old and which were more recent, because no technical record of the intervention in the façades of this building was found. Although all the tiles retain the aesthetic pattern of the nineteenth century, photographs indicate interventions in some tile’s facades that have been replaced by replicas. Mapping the state of conservation, chemical characterizing and identifying which tiles are old and which are recent were the main objectives of this research.Keywords: Historical tiles, chemical and mineralogical characterizations, restoration,
Biocompatible and Antibacterial Nitric Oxide-Releasing Pluronic F-127/Chitosan Hydrogel for Topical Applications
Authors: Pelegrino Milena T. , de Araujo Lima Bruna , do Nascimento Mônica H. M. , Lombello Christiane B. , Brocchi Marcelo , Seabra Amedea B.
Published: March 2018

Nitric oxide (NO) is involved in physiological processes, including vasodilatation, wound healing and antibacterial activities. As NO is a free radical, designing drugs to generate therapeutic amounts of NO in controlled spatial and time manners is still a challenge. In this study, the NO donor S-nitrosoglutathione (GSNO) was incorporated into the thermoresponsive Pluronic F-127 (PL) - chitosan (CS) hydrogel, with an easy and economically feasible methodology. CS is a polysaccharide with known antimicrobial properties. Scanning electron microscopy, rheology and differential scanning calorimetry techniques were used for hydrogel characterization. The results demonstrated that the hydrogel has a smooth surface, thermoresponsive behavior and good mechanical stability. The kinetics of NO release and GSNO diffusion from GSNO-containing PL/CS hydrogel demonstrated a sustained NO/GSNO release, in concentrations suitable for biomedical applications. The GSNO-PL/CS hydrogel demonstrated a concentration-dependent toxicity to Vero cells, and antimicrobial activity to Pseudomonas aeruginosa (minimum inhibitory concentration and minimum bactericidal concentration values of 0.5 µg·mL-1 of hydrogel, which corresponds to 1 mmol·L-1 of GSNO). Interestingly, the concentration range in which the NO-releasing hydrogel demonstrated an antibacterial effect was not found to be toxic to the Vero mammalian cell. Thus, the GSNO-PL/CS hydrogel is a suitable biomaterial for topical NO delivery applications.
Investigation of invitro Antioxidant and invivo Protective Effects of Hypericum triquetrifolium Seed Methanol Extracts against Cyclophosphamide-Induced Acute Myelotoxicity, Hemotoxicity and Hepatotoxicity in Rats
Authors: Cetik Yildiz Songul , Keskin Cumali , Ayhanci Adnan
Published: March 2018

The aim of this study was to investigate in-vitro antioxidant properties and in-vivo protective effects of different concentrations of Hypericum triquetrifolium Turra. (HT) seed methanol extracts against acute hepatotoxicity, myelotoxicity and hematotoxicity in rats exposed to overdose of cyclophosphamide (CP). HT seed methanol extracts were tested in view of its in-vitro antioxidant activities as total phenolic contents and DPPH free radical-scavenging activity. To investigate in-vivo protective effects of HT seed methanol extracts on rat tissues; tested animals were divided into nine groups. Three groups only were treated with HT extracts (25, 50 and 100 mg/kg HT) for 6 days. Three groups were pre-treated with the extract of HT (25, 50 and 100 mg/kg HT) for 6 days and on the last day they were injected with single dose of CP (150-mg/kg body weight). Two groups were used as control groups and one group was only treated with CP (150 mg/kg) on the 6th day. The toxic effects of CP and protective effects of HT extracts on the nucleated cells which were produced by bone marrow and serum alanine transaminase (ALT), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), oxidative stress index (OSI) levels were investigated biochemically. Additionally, liver tissue samples were examined histopathologically. Our results show that HT seed methanol extract has high total phenolic content and antioxidant activity. Over dose CP administration caused hepatotoxicity, myelotoxicity and hematotoxicity on rat. Whereas, 25, 50 and 100 mg/kg HT plus CP administered groups showed significant protective effects on nucleated cells. And 25, 50, 100 mg/kg HT plus CP treated groups showed an important decrease on serum ALT, ALP, LDH and OSI levels when compared with CP treated group. Our results showed that the administration of different HT doses with high doses of CP significantly reduced hepatotoxicity, myelotoxicity and hematoxicity on rats.
A Bibliographical Survey on Software Architectures for Smart Grid System
Authors: Ramesh A. , Karthikeyan Prabhakar , Padmanaban Sanjeevikumar , Balasubramanian Saravanan , M. Guerrero Josep
Published: March 2018

Smart grid software interconnects multiple Engineering disciplines (power systems, communication, software and hardware technology, instrumentation, big data, etc.). The software architecture is an evolving concept in smart grid systems in which systematic architecture development is a challenging process. The architecture has to realize the complex legacy power grid systems and cope up with current Information and Communication Technologies (ICT). The distributed generation in smart grid environment expects the software architecture to be distributed and to enable local control. Smart grid architecture should also be modular, flexible and adaptable to technology upgrades. In this paper, the authors have made a comprehensive review on architecture for smart grids. An in depth analysis of layered and agent based architectures is presented and compared under various domains.
Modelling Filler Dispersion in Elastomers: Relating Filler Morphology to Interface Free Energies via SAXS and TEM Simulation Studies
Authors: Gundlach Norman , Hentschke Reinhard
Published: March 2018

The properties of rubber are strongly influenced by the distribution of filler within the polymer matrix. Here we introduce a Monte Carlo-based morphology generator. The basic elements of our model are cubic cells, which, in the current version, can be either silica filler particles or rubber volume elements in adjustable proportion. The model allows the assignment of surface free energies to the particles according to whether a surface represents, for instance, 'naked' silica or silanised silica. The amount of silanisation is variable. We use a nearest-neighbour site-exchange Monte Carlo algorithm to generate filler morphologies, mimicking flocculation. Transmission electron micrographs (TEM) as well as small angle scattering (SAS) intensities can be calculated along the Monte Carlo trajectory. In this work we demonstrate the application of our morphology generator in terms of selected examples. We illustrate its potential as a tool for screening studies, relating interface tensions between the components to filler network structure as characterized by TEM and SAS.
Qualidade de vida e condições para se viver na pesca artesanal em Itanhaém-SP
Authors: PICCOLO Natali Isabela Pierin , MACHADO Ingrid Cabral , HENRIQUES Marcelo Barbosa
Published: March 2018

Novas contribuições í­Â  gestão pesqueira vêm sendo discutidas a partir de abordagens sobre bem-estar e qualidade de vida. No Brasil, a qualidade de vida (QV) e condições para se viver (QCV) foram avaliadas para comunidades rurais e aquicultores, com resultados objetivos que poderiam contribuir também í­Â  avaliação da atividade pesqueira de pequena escala. O presente trabalho buscou conhecer o distanciamento entre os olhares de pescadores e técnicos do municí­­pio de Itanhaém/SP sobre a atividade pesqueira em quatro dimensões: social, ambiental, econômica e governança, a partir de uma abordagem qualiquantitativa. A dimensão governança foi a mais crí­­tica e insatisfatória, implicando no menor indicador de qualidade de vida (IQV) e condições para se viver (IQLC), ressaltando a discussão sobre a necessidade de novos estudos sobre como os processos institucionais interferem no bem-estar da comunidade pesqueira da região.