bluuebunny/crossref_metadata_2025 huggingface dataset:
Plano de Empreendimento: APRENDA HOJE
Authors: Versiani Leandro
Published: January 2019

A aprenda Hoje é uma plataforma on-line de aulas particulares com foco em alunos universitários. Buscamos conectar alunos com dificuldades e/ou necessidade de aprofundamento em determinado conteúdo e professores que estão dispostos a dar aulas particulares. Para os alunos é uma maneira rápida de obter explicações específicas sobre conteúdos e tirar dúvidas. E para os professores é uma oportunidade de ampliar suas fontes de receitas, captando um número maior de estudantes. O negócio está estruturado em três camadas de serviço. A primeira camada, que tende a ser o foco da empresa, consiste nas aulas particulares ministradas on-line por meio de uma plataforma interativa, com uma sala de aula virtual, capaz de conectar professores de disciplinas específicas e alunos com dificuldades em conteúdos. A segunda camada abrange o mesmo público da primeira, porém disponibiliza o serviço de agendamento de aulas particulares presenciais. E a última camada de serviços visa aproveitar a base de pessoas cadastradas para divulgação e agendamento de palestras. Este último serviço será mais uma forma de gerar valor para os professores de nossa base de dados. Muitos desses profissionais já desenvolveram e/ou teriam facilidade para desenvolver palestras em seu tema de interesse. Mas poucos encontram um canal para divulgá-las e vendê-las.
Trajetórias do empreendedorismo imigrante e estratégias de mercado a partir das experiências de brasileiros no exterior
Authors: Picanço Eduardo , Falcão Roberto , Mancebo Rafael Cuba , Castro Andreia
Published: January 2019

O objetivo desse ensaio é o de identificar diferentes trajetórias de empreendedores imigrantes que são ilustradas através de comportamentos, e inspiradas tanto em evidências empíricas quanto nas teorias existentes a respeito do tema. Na proposta do modelo de trajetórias, destacam-se alguns fatores, como: a situação legal na entrada do país, o grau de escolaridade, experiências prévias de trabalho, proficiência na língua local, e o grau de conexão dos imigrantes, conformado dentro ou fora das comunidades étnicas. As trajetórias de cada tipo de imigração pesquisada configuram-se como caminhos únicos e possíveis. São ilustradas as trajetórias que retratam alguns tipos de empreendedores, baseados em suas histórias de vida. Os pesquisadores valeram-se da inspiração da literatura acadêmica no tema combinada com dados que emergiram do campo através de diversas técnicas de coleta - entrevistas em profundidade, observação participante, análise documental e surveys. De acordo com sua similaridade e representatividade, foram categorizadas nove possíveis trajetórias, que se configuram a partir de um processo decisório, combinando o efeito do ambiente com a história individual de cada imigrante, sendo explicadas ao longo do ensaio.
Planejamento estratégico para o setor joalheiro
Authors: Blois Henrique Dias , Scapin Tranquilo , Nunes Bruno Blois , Carvalho Maitê Peres de , Zilli Julcemar Bruno
Published: January 2019

Devido às mudanças no cenário econômico para o setor joalheiro do Brasil, aumentaram as incertezas quanto ao comportamento futuro do segmento, crescendo a necessidade de sistematizar previsões que antecipem o futuro. Para tanto, identificou-se estratégias ao setor joalheiro da região norte do Rio Grande do Sul para os próximos cinco anos, utilizando-se o método Grumbach para a criação de cenários prospectivos. Tal pesquisa foi aplicada a peritos do setor, os quais analisaram e propuseram eventos que impactaram como pontos fortes e fracos, oportunidades e ameaças e suas inter-relações. O cenário mais provável apresentou a probabilidade de 55,67% de ocorrência. No cenário de tendência, alguns eventos configuraram-se como possíveis mudanças de direção ao longo do tempo pré-estabelecido nesse estudo, são eles: (3) Aumento da produção e distribuição de joias com pouco planejamento; (4) Aumento do valor do dólar e (11) Aumento da crise econômica brasileira. Palavras-chave: Prospecção. Cenários. Joias. Planejamento. Administração.
Dos processos aos produtos de investigação: três propostas de avaliação de estudos científicos não positivistas
Authors: Ferreira Sónia Mairos
Published: January 2019

Resumo: O presente artigo constitui uma reflexão crítica acerca dos desafios e possibilidades que se colocam, na contemporaneidade, à avaliação da qualidade de investigação científica, quando esta se desenvolve segundo orientações de matriz não positivista. No âmbito da prossecução deste propósito a primeira rubrica contém uma breve síntese das (in)suficiências, reportadas na literatura, no que respeita ao positivismo e, também, às propostas alternativas defendidas pelos/as seus/suas críticos/as. A rubrica seguinte sintetiza três tendências de apreciação da qualidade de estudos científicos não positivistas, apontando as particularidades que assumem, assim como as divergências que possuem, em relação ao positivismo e, igualmente, entre si.Palavras-chave: Conhecimento científico; Investigação (não) positivista; Avaliação. From processes to research products: three proposals of evaluation of non-positivistic scientific studiesAbstract: This article is a critical reflection on the challenges and opportunities that arise, in contemporaneity, to the evaluation of the quality of scientific research, when it develops accordingly to non-positivist guidelines. In pursuing this purpose the first rubric contains a brief overview of the (in)sufficiencies, reported in the literature, regarding positivism and, also, to alternative proposals advocated by its critics. The following rubric synthesizes three trends of assessing the quality of non-positivist scientific studies, pointing out the particularities they assume, as well as the major differences from positivism and from each other.Keywords:
Apresentação da Seção Temática
Authors: Boscarioli Clodis
Published: January 2019

Na chamada para este dossiê temático dedicado à Pesquisa Qualitativa acerca de Tecnologias Educacionais na Educação Inclusiva, foram convidados à submissão trabalhos de investigação (preferencialmente qualitativos) sobre a inclusão escolar dos estudantes público alvo da Educação Especial, sob diferentes perspectivas, com particular interesse nos estudos voltados às ações de inclusão mediadas pelo uso de tecnologias digitais e/ou desenvolvimento da Tecnologia Assistiva.
HUBUNGAN TINGKAT PENGETAHUAN MENGENAI RISIKO KEHAMILAN DENGAN PERILAKU SEKSUAL REMAJA DI KELURAHAN MANGGA DUA SELATAN
Authors: Lestari Puspita Hanggit
Published: January 2019

Permasalahan seksual pada remaja tidaklah terbatas hanya masalah fisik tetapi juga secara psikis seperti perasaan ingin tahu terhadap masalah-masalah seksual.  Penyimpangan perilaku seksual remaja berdampak pada risiko sistem reproduksi remaja, antara lain resiko kehamilan di luar nikah, aborsi pada kehamilan remaja, rentan terhadap HIV/AIDS dan berbagai penyakit menular seksual, gangguan saluran reproduksi dan gangguan psikososial. Tujuan penelitian ini adalah mengetahui adanya hubungan tingkat pengetahuan mengenai resiko kehamilan dengan perilaku seksual remaja. Penelitian cross-sectional ini menggunakan teknik purposive random sampling dengan 78 responden siswa SMA di Jakarta Barat. Penelitian mengkaji tingkat pengetahuan risiko kehamilan dan perilaku seksual remaja menggunakan kuesioner. Hasil penelitian menunjukkan bahwa terdapat hubungan yang bermakna antara tingkat pengetahuan remaja mengenai resiko kehamilan pada usia remaja dengan perilaku seksual remaja. Berdasarkan hal tersebut remaja memerlukan bantuan dan pemantauan orang tua atau orang yang lebih dewasa dalam memahami info yang benar terkait seksualitas.
KARAKTERISTIK PENGETAHUAN TENTANG LAKTASI DENGAN TEKNIK MENYUSUI PADA KALANGAN KADER POSYANDU DI KOTA MALANG
Authors: Daramatasia Wira
Published: January 2019

Data kesehatan di Kota Malang diketahui bahwa cakupan ASI eksklusif pada tahun 2009 sebesar 58,47%, cakupan ASI eksklusif ini masih relatif rendah jika dibandingkan dengan target nasional 80%. Untuk mencapai keberhasilan pemberian ASI pada bayi harus didukung oleh manajemen laktasi yang baik dan teknik menyusui yang tepat agar manfaat dari ASI lebih maksimal. Peran aktif kader posyandu dalam menyumbangkan tenaga dan pikirannya untuk meningkatkan kesehatan masyarakat sangatlah penting. Penelitian ini bertujuan untuk mengetahui karakteristik pengetahuan tentang laktasi dengan teknik menyusui pada kalangan kader posyandu di kota Malang, serta hubungan pengetahuan dengan sikap kader posyandu mengenai teknik menyusui. Metode penelitian ini adalah Survey Analitik dengan pendekatan cross sectional. Pengambilan sampel dengan teknik simple random sampling. Jumlah sampel penelitian ini berjumlah 50 responden dari jumlah populasi kader posyandu yang mewakili 5 kecamatan di Kota Malang. Instrumen penelitian ini menggunakan kuesioner dan lembar observasi berupa checklist. Data yang diperoleh yaitu karakteristik responden meliputi usia, pendidikan, pekerjaan, dan masa/lama menjadi kader posyandu, kemudian variable pengetahuan tentang laktasi dan tehnik menyusui kader posyandu. Analisis data menggunakan Korelasi Somers’d. Hasil penelitian diperoleh bahwa pengetahuan kader posyandu mengenai menyusui sebagian besar baik sejumlah (68%), Sikap kader posyandu mengenai teknik menyusui sebagian besar kurang (62%). Tidak terdapat korelasi yang bermakna antara pengetahuan kader posyandu dengan sikap mengenai tehknik menyusui (p>0,05).
HUBUNGAN PENGETAHUAN DENGAN AKURASI PENGAMBILAN KEPUTUSAN PERAWAT DALAM PELAKSANAAN TRIAGE
Authors: Harianto Purwoko Sugeng
Published: January 2019

Instalasi Gawat Darurat (IGD) memberikan pelayanan perawatan selama 24 jam setiap harinya. Triage merupakan aktivitas awal yang dilakukan perawat ketika pasien datang ke IGD. Triagemerupakan proses memilahpasien menurut tingkat keparahannya. Akurasi keputusan triage mempunyai dampak yang signifikan pada outcome pasien. Pada kenyataanya masih banyak perawat yang bekerja di IGD memiliki pengetahuan dan keterampilan yang kurang tentang triage.Pengetahuan dan ketrampilan mempunyai hubungan dengan pelaksanaan triage.Secara umum,terdapat dua faktor yang mempengaruhiakurasi pengambilan keputusanperawat dalam pelaksanaan triage.Faktor pertama adalah faktor internal yang menggambarkan tentang pengetahuan, pengalaman kerja dan pelatihan perawat, sedangkan faktor kedua merupakan faktor eksternal meliputi hal-hal yang berhubungan dengan lingkungan kerja dan beban kerja.Pengabaian terhadap faktor internal dan eksternal dapat menyebabkan pelaksanaan triage menjadi tidak akurat dan mengakibatkan kecacatan permanen pada pasien.

 

Tujuan penelitian ini adalah menganalisis hubungan pengetahuan dengan akurasi pengambilan keputusan perawat dalam pelaksanaan triage di IGD RSUD Dr. Saiful Anwar Malang. Penelitian ini menggunakan desain analitik korelasional dengan pendekatan cross sectional. Pengambilan data dilakukan tanggal 15 April sampai 15 Mei 2015 dengan jumlah sampel 50 responden.Pengambilan data menggunakan instrument lembar kuesioner dan lembar observasi.Analisis bivariat menggunakan korelasi Pearson. Hasil penelitian menunjukkan ada hubungan antara pengetahuan dengan akurasi pengambilan keputusan perawat dalam pelaksanaan triage(p value=0.000<∝) dengan koefisien korelasi 0.565. Diharapkan pihak rumah sakit dapat meningkatkan pengetahuan, keterampilan dan kompetensi perawat IGD melalui pendidikan berkelanjutan dan pelatihan triage officer.
Hubungan Antara Konsumsi lemak, Obesitas Dan Aktovitas Fisik Dengan Hipertensi Usia Monopause
Authors: Firyal Fadia Rifqi Ayu
Published: January 2019

Hipertensi merupakan penyebab penyakit kardiovaskular, stroke, gagal ginjal dan menyebabkan morbiditas dan mortalitas baik pada pria maupun wanita. Peningkatan prevalensi terjadi pada negara maju, namun juga pada sejumlah negara berkembang di dunia. Prevalensi meningkat seiring bertambahnya usia terutama setelah wanita menopause. Peningkatan risiko pada wanita menopause dipengaruhi adanya perubahan hormonal, pengaruh pola konsumsi seperti konsumsi lemak, adanya obesitas dan juga kurangnya aktivitas fisik. Tujuan penelitian ini yaitu untuk mengetahui hubungan antara konusmsi lemak, obesitas dan aktivitas fisik dengan hipertensi usia menopause. Penelitian ini menggunakan desain case control study dan jenis penelitian retrospektif dengan populasi penelitian yaitu pasien wanita ≥ 45 tahun di poli jantung RSU Haji Surabaya. Besar sampel penelitian ini adalah sejumlah 64 responden. Teknik sampling yang digunakan yaitu simple random sampling.   Teknik pengumpulan data menggunakan wawancara dengan kuesioner serta pengukuran BMI untuk mengukur berat badan dan tinggi badan. Analisis data dengan uji chi-square untuk menguji hubungan variabel independen terhadap variabel dependen. Hasil penelitian menunjukkan konsumsi lemak (p value = 0,042) dan aktivitas fisik (p value = 0,046) bermakna secara signifikan (nilai p < 0,05) terhadap hipertensi usia menopause. Sedangkan variabel obesitas (p value = 0,614) menunjukkan hasil yang tidak bermakna secara signifikan.
Pengaruh Sikap Dan Persepsi Ibu Terhadap Dukungan Tokoh Agama Serta Dukungan keluarga Terhadap Status Kelengkapan Imunisasi dasar Bayi
Authors: Daman Nur jelita Amin , Hargono Arief
Published: January 2019

Hepatitis B, Tuberculosis, Polio, Campak, Difteri, Pertusis dan Tetanus Neonatorum masih menjadi masalah kesehatan global karena menimbulkan kesakitan, kecacatan dan kematian. Pemerintah berupaya mengatasinya melalui program imunisasi dasar lengkap (IDL) dengan target cakupan 91% dan target Universal Child Immunization (UCI) sebesar 84% untuk tahun

2015, sedangkan wilayah kerja Puskesmas Geger hanya mampu mencapai IDL sebesar 46,4% dan UCI 15,4%. Tujuan dilakukannya penelitian ini adalah untuk menganalisis faktor ibu yang mempengaruhi status kelengkapan imunisasi dasar bayi di Wilayah Puskesmas Geger Kabupaten Bangkalan. Desain penelitian Case Control dengan teknik cluster sampling diterapkan dalam penelitian ini dan diperoleh sampel 39 kasus dan 39 kontrol yang terbagi secara proporsi di 6 cluster (desa). Variabel bebas dalam penelitian ini adalah sikap, persepsi ibu terhadap dukungan tokoh agama, dan persepsi ibu terhadap dukungan keluarga. Hasil uji statistik menunjukkan bahwa status kelengkapan imunisasi dasar bayi dipengaruhi oleh sikap ibu (p = 0,001) dan persepsi ibu terhadap dukungan keluarga (p = 0,002). Sikap buruk ibu terhadap imunisasi dan buruknya persepsi ibu terhadap dukungan keluarga mempengaruhi ketidaklengkapan status imunisasi dasar bayi. Disarankan perlu ada perluasan mitra dan sasaran promosi kesehatan tentang imunisasi untuk meningkatkan kesadaran dan kepercayaan masyarakat akan pentingnya imunisasi dasar lengkap bagi bayi
Tingkat pencemaran Logam Berat Khromium VI (CRVI) Pada Air Sumur (Studi Kasus di Home Industri Poles Dan Chrom ''X'' Kelurahan Bumi Ayu Kota Malang
Authors: Yuliati Lilik
Published: January 2019

Khromium adalah logam dengan berat atom 51,966. Toksisitas Khromium dapat mengakibatkan keracunan akut dan kronis seperti kanker paru-paru dan dermatitis. Industri Poles dan Chrom “X” di Kelurahan Bumi Ayu Kota Malang adalah home industri pelapisan logam,yang mana proses produksinya menghasilkan limbah cair yang mengandung Khromium, dan tidak ada pengelolaan limbah cair yang dilakukansebelum dibuang ke sumur resapan. Hal itu dapat mencemari air sumur yang masih digunakan untuk keperluan sehari-hari. Untuk itu penelitian ini dilakukan dengan tujuan mengetahui tingkat pencemaran logam Khromium VI (Cr VI)  pada air sumur home industri poles dan Chrom “X” di Kelurahan Bumi Ayu  Kota Malang dan analisis risiko kesehatan lingkungan.

Metode penelitian yang digunakan adalah deskriptif. Populasi dalam penelitian ini adalah air sumur di home industri Poles dan Chrom “X”. Teknik pengambilan sampel dilakukan dengan total samplingsejumlah 1sumur. Data primer didapat melalui wawancara langsung dan uji kandungan Cr VI pada air sumur di Laboratorium Perum. Jasa Tirta dengan Metode Kolorimetri. Hasil  penelitian disajikan dalam tabulasi dan dianalisis secara  deskriptif.

Hasil  dari  penelitian  ini menunjukkan ada pencemaran logam berat Cr VI pada air sumur ( < 0,012 mg/l )  meskipun belum melebihi batas maksimal yaitu 0,05 mg/l (Permenkes 32, 2017 ). Hasil ARKL konsentrasi Cr VI < 0,012 mg/l tergolongmasih aman ( RQ<1)  untuk anak-anak dan orang dewasa. Berkenaan dengan hasil tersebut  perlu dilakukan pengelolaan limbah cair sebelum dibuang ke sumur resapan. Disamping itu perlu dilakukan  pemantauan oleh dinas terkait dan edukasi bagi masyarakat sekitar dan pemilik home industri.
DINAMIKA KERUKUNAN UMAT BERAGAMA KOTA AMBON BERBASIS ADAT PERSPEKTIF MASLAHAH
Authors: Muher Abdul
Published: January 2019

The dynamic of religious society peacefulness in Ambon on the base of custom from maslahah perspective has been undoubtedly effective and benefitful to maintain peacefulness and tolerance. Local values such as: a. Ale rasa beta rasa, to feel each other), has been effective in the comtext of tolerance in religious live. These local values are humanity expressions of different religions to share both happiness and bitterness together; b. Katong samua basudara, basicly express men are brothers of one anxious; c. Siwa Lima, to unite Ambonese without differsity), and functionally unite the whole native Ambon-Maluku society and the comers without seeing their religions; d. Pela gandong, which is corresponding Moslems to Moslems, Christians to Christians, and Moslems to Christians).
SEJARAH PEMIKIRAN EKONOMI ISLAM AL SYAIBANI DAN ABU UBAID
Authors: Wally Salidin
Published: January 2019

This article describes about the Islamic economic thinking according to Islamic economist Al Syaibani and Abu Ubaid. In his discussion raised the thinking of two prominent Islamic economist Al Syaibani who emphasized his thoughts on microeconomics and embodied in his work namely Al-Kasb, and also Abu Ubaid's ideas which emphasize his thoughts on macroeconomics by exploring in detail in his book that is Al-Amwal discusses state rights and obligations. And concluded that the thoughts of these two figures differed in view in response to economic problems, but both have a common goal that is for the welfare of the ummah and the main goal of the keridhoan Allah.
E-MONEY DALAM PERSPEKTIF HUKUM EKONOMI SYARIAH
Authors: Firdaus Muhammad Ridwan
Published: January 2019

Money as a medium of exchange in economic activities always changes, both in form, intrinsic value, and extrinsic value. Islam as a universal religion and as a way of life, regulates new symptoms that arise in society. The halal use of electronic money is still in doubt by the public. Because the form that is not visible is only how many numbers, and in the form of digital code on a chip or server. This goal aims to find the common value and position of electronic money. Research is limited to tcash issued by PT. Telkomsel. The results of the study found that electronic money is only a service offered by publishers to simplify and streamline the process of economic transactions.
TINJAUAN YURIDIS KEDUDUKAN HUKUM PARA PIHAK DALAM PERJANJIAN TERAPEUTIK
Authors: Gani Evy Savitri
Published: January 2019

This paper examines the legal status of the parties to the therapeutic agreement. The problem in this paper is how the legal status of the parties to the treaty is therapeutic and what is the legal protection for the patient in the therapeutic covenant. Data were collected through review of laws, books or literature and analyzed descriptively qualitatively. The results showed that the position of the parties between patients and doctors according to law equal or balanced. This is reflected in the rights and obligations set forth in the legislation in the field of health. While the form of legal protection is also reflected in Law Number 36 Year 2009 on Health, Law Number 29 Year 2004 About Medical Practice and Law Number 8 Year 1999 About Consumer Protection.
Analisis Perbandingan Metode Fuzzy Tsukamoto, Mamdani dan Sugeno dalam Pengambilan Keputusan Penentuan Jumlah Distribusi Raskin di Bulog Sub. Divisi Regional (Divre) Cianjur
Authors: Widaningsih Sri
Published: January 2019

Beras untuk penduduk miskin (raskin) merupakan salah satu program pemerintah untuk meningkatkan kesejahteraan penduduk miskin yang dikelola oleh Bulog. Permasalahan yang terjadi yaitu sering kurang tepatnya pemberian jumlah raskin dibandingkan dengan jumlah penduduk miskin yang ada di suatu kota/kabupaten diantaranya Kabupaten Cianjur. Salah satu model yang dapat digunakan untuk pengambilan keputusan jumlah distribusi raskin adalah model logika fuzzy karena model ini dapat menangani data-data yang tidak linier. Pada penelitian ini dilakukan perbandingan antara ketiga metode sistem inferensia fuzzy yang sering digunakan yaitu metode Tsukamoto, Mamdani, dan Sugeno. Variabel input berupa jumlah penduduk miskin dan jumlah rata-rata stok, sedangkan variabel output berupa jumlah distribusi raskin. Untuk mengevaluasi output digunakan dua teknik yaitu perbandingan standar eror dan uji hipotesis t-test. Dari ketiga metode diperoleh nilai MAPE masing-masing untuk metode Tsukamoto (28,05%), Mamdani(39,05%), dan Sugeno (7,45%). Untuk uji hipotesis hanya metode Sugeno yang hipotesisnya diterima sehingga dari dua teknik evaluasi output, metode Sugeno yang terbaik untuk pengambilan keputusan jumlah distribusi raskin di Cianjur
Peluang Keamanan Password dalam Transaksi Perbankan
Authors: Junaedi Dani Indra
Published: January 2019

Teknologi sudah menjadi unsur utama dalam pelayanan jasa perbankan. Setiap nasabah memiliki akun yang bisa dimanfaatkan untuk berbagai fitur layanan perbankan. Untuk mengakses akun tersebut diperlukan password yang secure supaya tidak mudah diakses oleh orang lain. Keamanan Password menjadi syarat utama dalam keamanan suatu akun perbankan dimana pembobolan rekening nasabah dapat dihindari.Teknis pembuatan password harus mengandung karakter angka, huruf (besar kecil) dan simbol supaya tidak mudah ditebak. Semakin lengkap karakter yang digunakan dan semakin banyak jumlah karakter akan membuat password semakin aman. Walaupun secara penghitungan peluang pembobolan sangat kecil, namun perilaku social engineering tetap dianggap sebagai potensi yang membahayakan bagi keamanan suatu akun. Dalam social engineering, si pelaku memanfaatkan sifat alamiah dari manusia. Hal ini diartikan bahwa betapa sifat alami manusia dapat diketahui dan dipelajari juga dimanfaatkan untuk tujuan tertentu. Kejahatan social engineering sangat membahayakan bisnis perbankan karena berpotensi menimbulkan kerugian finansial, reputasi dan hukum bagi bank dan nasabahnya melalui serangan fisik dan serangan psikologis. Dalam tulisan ini juga akan diberikan solusi bagaimana membuat suatu password dan mengelola password supaya benar-benar aman bagi pengguna
Penerapan Strategi Social Media Marketing Untuk Meningkatkan Penjualan Pada Dealer Mobil Toyota, Daihatsu dan Honda Bandung
Authors: Akbar Yopi Hidayatul , Helmiawan Muhammad Agreindra
Published: January 2019

Social media is one of the information media that is currently widely used by several companies and personally to convey information, with the presence of social media companies no longer need to spread offers through print media, they can use information technology tools in this case social media to submit offers the products they sell to users globally through social media. This social media marketing technique is the process of reaching visits by internet users to certain sites or public attention through social media sites. Marketing activities using social media are usually centered on the efforts of a company to create content that attracts attention, thus encouraging readers to share the content through their social media networks. The application of the QMS method is certainly not only submitted through search engine webmasters, but also on a website keywords must be applied that relate to the contents of the website content, because with the keyword it will automatically attract visitors to the university website based on keyword phrases that they type in the search engine. With Search Media Marketing Technique (SMM) is one of the techniques that must be applied in conducting sales promotions, especially in car dealers in Bandung, it is considered important because each product requires price, feature and convenience socialization through social media so that sales traffic can increase. Each dealer should be able to apply the techniques of Social Media Marketing (SMM) well so that car sales can reach the expected target and provide profits for sales as car sellers in the field.
PENGETAHUAN PASIEN TENTANG PENYAKIT DEMAM BERDARAH DENGUE DI POLIKLINIK UMUM PUSKESMAS POASIA KOTA KENDARI
Authors: Taamu Taamu , Misbah Sitti Rachmi , Purnama Arif
Published: January 2019

Dengue hemorrhagic fever is a disease caused by dengue virus that enter into human body through Aedes aegypti mosquito bites. Dengue Hemorrhagic Fever case in Southeast Sulawesi province from January to February 2016 has reached 530 cases with 3 deaths or 0,57%. This study aims to determine the description of patient knowledge about the causes, signs and symptoms, prevention and management of dengue fever. The sample in this research is obtained by accidental sampling technique as many as 82 people from the total population of 821 people who are patients in Public Health Center of Kendari Polyclinic. The results showed that the patient had sufficient knowledge of DHF on the aspect of cause as much as (43,9%), sign and symptom aspect as much (53,66%), prevention aspect as much (50,00%) while the management aspect, (45.12%). The conclusion of this study is that the majority of patients in the Public Polyclinic of Poasia City Health Center have sufficient knowledge on the causal aspects, signs and symptoms and preventive measures against dengue hemorrhagic fever. While in the management aspect of dengue hemorrhagic disease majority of patients have knowledge of good.
KEBIASAAN MENCUCI TANGAN PADA ANAK SEKOLAH DENGAN KEJADIAN KECACINGAN DI DAERAH PESISIR DESA TADUI KECAMATAN MAMUJU
Authors: Saeni Rahmat Haji , Arief Erdiawati
Published: January 2019

The World Health Organization (WHO) in 2011 estimates that more than 2 billion people are infected with worms around the world, about 300 million suffer from severe worm infections and about 150,000 deaths occur annually due to STI (Soil transmitted helminths) infections. Deworming has a major impact on society because it affects intake, digestion, absorption and food metabolism. Cumulatively worm infections can cause nutritional loss of calories and proteins and blood loss that can cause anemia, inhibit physical development, mental, intellectual decline in children and work productivity, can decrease the body's resistance so easily affected by other diseases. The purpose of this study was to determine the relationship between hand washing habits and bathing habits with the incidence of worms. The research method used is cross sectional. The results of this study showed that there was a relationship between hand washing before eating and hand washing after  to the occurrence of worm infestation with p value of 0.02 and 0.04 respectively. The relationship of bathing habits also showed a statistical relationship with a p value of 0.03, whereas there was feces in the nails also showed a statistical relationship with a p value of 0.00. Conducting efforts to promote clean and good living behavior both at school and community. Improve the promotion of handwashing, especially handwashing with soap.
FAKTOR YANG BERHUBUNGAN DENGAN PEMBERIAN KOLOSTRUM PADA BAYI BARU LAHIR DI RSKDIA PERTIWI MAKASSAR
Authors: Harun Ayatullah , Jumriani Jumriani
Published: January 2019

Colostrum represents the first fluid that secreted by the breast gland, containing tissue debris and residual material in the alveoli and ducts of the breast glands pre- and post-puerperium. It is also viscous liquid with yellowish color and more yellow than mature milk (Wulandari & Handayani, 2011). This research aimed to determine the relationship of mother knowledge, family support and health officers by giving colostrum at RSKDIA Pertiwi Makassar. The methods of research by using anaytical design with cross sectional study apparoach, the sample of research is post-partum mother as many as 122 mothers. The result of research indicates that there is significant correlation between mother’s knowledge with the giving of colostrum for newborn with p-value = 0.014 < α = 0.05, there is no significant correlation between family support and the giving of colostrum with p-value = 0.79 > α = 0.05 and there is no correlation between health officer support with the giving of colostrum with p-value = 0.283 > α = 0.05. It can be concluded that there is a relationship between mother’s knowledge with the giving of colostrum and there is no relationship between family support, and health officer support with the giving of colostrum. It is expected that mothers can increase their knowledge about colostrum delivery for newborn by following counseling of health officer as well as increasing the role of health officer by giving health program especially in improving the understanding of communities about the importance of colostrum.
HOSPITALISASI MEMPENGARUHI TINGKAT KECEMASAN ANAK TODDLER
Authors: A. Pulungan Zulhaini Sartika , Purnomo Edi , Purwanti A. Arni
Published: January 2019

Hospitalization can cause anxiety and stress at all age levels. The cause of anxiety is influenced by many factors, both from the officer factor (nurses, doctors and other health personnel), the new environment, and the accompanying family during the treatment. Children sometimes perceive hospitalization as punishment so that children will feel shame, guilt, or fear. This leads to aggressive reactions such as anger and rebellion, verbal expression by saying angry words, not cooperating with nurses, thus affecting the treatment process while in hospital. The present study aimed at investigating the effect of hospitalization on anxiety levels of toddler in Puskesmas Tampa Padang. This research is an descriptive research with cross sectional design. Research subjects taken by purposive sampling counted 63 people. The data were analyzed using fisher's exact test. The results showed that hospitalization influenced toddler child's anxiety level (p 0.005). It is expected that health workers continue to provide good services and continue to maintain communication to children and families so that children feel comfortable during the process of hospitalization.
ANALISIS KANDUNGAN BORAKS PADA BAKSO YANG DIJUAL DI ANDUONOHU KOTA KENDARI SULAWESI TENGGARA
Authors: Misbah Sitti Rachmi , Darmayani Satya , Nasir Narti
Published: January 2019

Fast food consumption today has become a habit of eating for the people in Indonesia. One of the popular fast food is meatballs, but nowadays often found the use of non-food additives in the meatballs, namely borax. The Indonesian Republic Food and Drug Administration has detected the abusive use of borax on food derived from various regions of Indonesia. Borax is a chemical compound derived from heavy metals, namely Boron and commonly used as an anti-fungal and wood preservative. This study aimed to determine the content of borax on meatballs that was sold in Anduonohu, Kendari City of Southeast Sulawesi. Type of research using total sampling conducted by observational descriptive by the qualitative method that was using the method of centrifugation and dry ash processing. The results showed that from 24 samples of meatballs located in Anduonohu, Kendari City, it was proven that none of the meatballs contained borax which could endanger the consumer's health which was marked by no change of green color when heated on the flame. Based on the results of the analysis can be concluded that all sellers of meatballs located in Anduonohu, Kendari City have the knowledge and good attitude. Knowledge and attitude level is one important factor in order to avoid pollution of toxin material. Meatball processing method in Anduonohu, Kendari City has fulfilled the requirement of Indonesian Republic Health Minister Regulation in 2015, Number: 722/Menkes/Per /IX/2015 about food, so people do not have to worry about consuming meatballs located in Anduonohu, Kendari City.
In vitro effect of tuibur (tobacco brew) on the viability of human blood lymphocytes
Authors: Lalruatfela B. , Zoremsiami Jennifer , Jagetia Ganesh Chandra
Published: January 2019

The use of tobacco and its products are known to cause many illnesses including cancer. A smokeless tobacco locally manufactured called tuibur (tobacco brew) has been consumed by the Mizos from a very long time. In this experiment we aim to determine the cytotoxicity of tuibur by an in vitro study on tuibur-treated human peripheral blood lymphocytes. We have found that 24 h treatment of human lymphocytes with two grades of commercial tuibur and nicotine showed a concentration dependent decrease in cell viability. We, therefore, concluded that as the in vitro use of tuibur has an adverse effect on cell survival, its consumption might have potential side effects on the health of the users.
Enumeration of ethno-medicinal plants in Rongram Block of West Garo Hills District, Meghalaya
Authors: Marak Nadaline M. , Lalnundanga
Published: January 2019

A study was conducted to enumerate the ethno-medicinal plants in Rongram block of West Garo Hills District, Meghalaya. The study was based on the primary survey and data collected through questionnaires, focus-group discussions and semi-structured interviews prepared for the purpose by approaching the local traditional healers (oja) as well as villagers. The study revealed that a total of 18 medicinal plants belonging to 18 genera and 16 families were documented. Information on local names, scientific names, family, plant parts used and traditional usage of these plants were also reported. Among the documented medicinal plant species, trees were most frequently used followed by herbs, shrubs and climbers. The study also revealed that leaves were most commonly used in the treatment followed by the bark.
Comparison of single and double entry twin cup dosimeter in measuring indoor radon and thoron concentration in Mizoram, India
Authors: Chhangte L.Z. , Rohmingliana P.C. , Sahoo B.K. , Sapra B.K. , Vanramlawma  , Hmingchungnunga  , Remlalsiama  , Pachuau Z. , Zoliana B.
Published: January 2019

Indoor radon and thoron concentrations have been measured using solid state nuclear track detector (LR-115 type-ІІ) based twin cup dosimeter with single and double entry deployed side by side. The measurements have been carried out in 50 dwellings of 8 different villages/towns situated in Saiha and Lawngtlai districts, Mizoram. Dwellings were selected primarily from the gamma level measured using Micro-R survey meter and the construction type of the building. The average concentrations of radon and thoron were found to be 75.76 Bq/m3 and 96.50 Bq/m3 for single entry dosimeter and 63.47 Bq/m3 and 19.79 Bq/m3 for double entry dosimeter. The single entry dosimeter was found to give more reliable observations than that of double entry in terms of trends of seasonal data and also on the theory behind the manufacturing qualities.
Effect of seasonal variation on soil enzymes activity and fertility of soil in paddy fields of North Vanlaiphai, Mizoram, India
Authors: Vanlalveni C. , Lalfakzuala R.
Published: January 2019

For sustainability in agricultural productions, familiarity of soil quality and manual improvement to create the best possible growing environment for plants are extremely important. In this study the quality of soil of a paddy field in North Vanlaiphai was investigated with respect to the change in seasons throughout the year. A total of five (5) soil samples were selected from various places of the paddy field, and soil fertility indicators such as pH, total soil nitrogen (N), available phosphorus (Pav), exchangeable potassium (Kex), soil organic carbon (SOC), soil organic matter (SOM) and soil enzymes viz. dehydrogenase, phosphatase and urease were analyzed using standard protocols. All the parameters except available phosphorus and exchangeable potassium were found to be highest during rainy season whereas lowest in summer.
Sightings of chestnut-flanked white-eye Zosterops erythropleurus: First report from Mizoram, India
Authors: Sailo Lalawmawia , Chhangte Lawmsangzuala , Aineh Rochamliana , Lalthanzara H.
Published: January 2019

In this paper we report the first confirmed sighting of chestnut-flanked white-eye Zosterops erythropleurus (Swinhoe, 1863) from Mizoram and first photographic report from India. chestnut-flanked white-eye belongs to the family Zosteropidae and is a resident of Cambodia, China, Hongkong, Korea, Democratic People’s Republic of Korea, Laos, Myanmar, Russia, Thailand and Vietnam. In the Indian Sub-continent this is the only sighting report for this species and details of sightings and habitat are discussed.
Some pharmacognostic studies of the cogon grass Imperata cylindrica from Mizoram, India
Authors: Lalthanpuii P.B. , Zarzokimi  , Lalchhandama K.
Published: January 2019

Cogon grass Imperata cylindrica is a perennial grass belonging to the family Poaceae, and the rhizome-root portion of which is used for the treatment of bacterial infections, ringworms and other skin infections. Among the Mizo people they are directly consumed or juiced for the treatment of intestinal infection. Its chemical and biological properties are poorly documented. In this study, a methanol extract of the rhizome-root was prepared by hot extraction in a Soxhlet apparatus. Standard chemical tests were conducted. The presence of alkaloids, carbohydrates including reducing sugars, phytosterols, tannins, saponins and proteins were confirmed as the major bio-compounds. Free radical-scavenging activities were also determined. The plant extract indicated concentration-dependent scavenging activity on DPPH with an inhibitory concentration (IC50) of 2.14 µg/ml. H2O2 was similarly scavenged, in which the IC50 was 2.221 µg/ml. Our results suggest that I. cylindrica has important medicinal values.
Performance Enhancement of Internal Combustion Engines through Vibration Control: State of the Art and Challenges
Authors: Mahdisoozani Hojat , Mohsenizadeh Mehrdad , Bahiraei Mehdi , Kasaeian Alibakhsh , Daneshvar Armin , Goodarzi Marjan , Safaei Mohammad Reza
Published: January 2019

Internal combustion engines (ICEs) are the primary source of power generation in today’s driving vehicles. They convert the chemical energy of the fuel into the mechanical energy which is used to drive the vehicle. In this process of energy conversion, several parameters cause the engine to vibrate, which significantly deteriorate the efficiency and service life of the engine. The present study aims to gather all the recent works conducted to reduce and isolate engine vibration, before transmitting to other vehicle parts such as drive shafts and chassis. For this purpose, a background history of the ICEs, as well as the parameters associated with their vibration, will be introduced. The body of the paper is divided into three main parts: First, a brief summary of the vibration theory in fault detection of ICEs is provided. Then, vibration reduction using various mechanisms and engine modifications is reviewed. Next, the effect of using different biofuels and fuel additives, such as alcohols and hydrogen, is discussed. Finally, the paper ends with a conclusion, summarizing the most recent methods and approaches that studied the vibration and noise in the ICEs.
The PERK Branch of the Unfolded Protein Response Promotes DLL4 Expression by Activating an Alternative Translation Mechanism
Authors: Jaud Manon , Philippe Céline , Van Den Berghe Loic , Ségura Christèle , Mazzolini Laurent , Pyronnet Stéphane , Laurell Henrik , Touriol Christian
Published: January 2019

Delta-like 4 (DLL4) is a pivotal endothelium specific Notch ligand that has been shown to function as a regulating factor during physiological and pathological angiogenesis. DLL4 functions as a negative regulator of angiogenic branching and sprouting. Interestingly, Dll4 is with Vegf-a one of the few examples of haplo-insufficiency, resulting in obvious vascular abnormalities and in embryonic lethality. These striking phenotypes are a proof of concept of the crucial role played by the bioavailability of VEGF and DLL4 during vessel patterning and that there must be a very fine-tuning of DLL4 expression level. However, to date the expression regulation of this factor was poorly studied. In this study, we showed that the DLL4 5′-UTR harbors an Internal Ribosomal Entry Site (IRES) that, in contrast to cap-dependent translation, was efficiently utilized in cells subjected to several stresses including hypoxia and endoplasmic reticulum stress (ER stress). We identified PERK, a kinase activated by ER stress, as the driver of DLL4 IRES-mediated translation, and hnRNP-A1 as an IRES-Trans-Acting Factor (ITAF) participating in the IRES-dependent translation of DLL4 during endoplasmic reticulum stress. The presence of a stress responsive internal ribosome entry site in the DLL4 msRNA suggests that the process of alternative translation initiation, by controlling the expression of this factor, could have a crucial role in the control of endothelial tip cell function.
Numerical Simulation and Optimization of Waste Heat Recovery in a Sinter Vertical Tank
Authors: Xu Chenyi , Liu Zhichun , Wang Shicheng , Liu Wei
Published: January 2019

In this paper, a two-dimensional steady model is established to investigate the gas-solid heat transfer in a sinter vertical tank based on the porous media theory and the local thermal non-equilibrium model. The influences of the air flow rate, sinter flow rate, and sinter particle diameter on the gas-solid heat transfer process are investigated numerically. In addition, exergy destruction minimization is used as a new principle for heat transfer enhancement. Furthermore, a multi-objective genetic algorithm based on a Back Propagation (BP) neural network is applied to obtain a combination of each parameter for a more comprehensive performance, with the exergy destruction caused by heat transfer and the one caused by fluid flow as the two objectives. The results show that the heat dissipation and power consumption both gradually increase with an increase of the air mass flow rate. Additionally, the increase of the sinter flow rate results in a decrease of the heat dissipation and an increase of the power consumption. In addition, both heat dissipation and power consumption gradually decrease with an increase of the sinter particle diameter. For the given structure of the vertical tank, the optimal operating parameters are 2.99 kg/s, 0.61 kg/s, and 32.8 mm for the air flow rate, sinter flow rate, and sinter diameter, respectively.
The Cancer Aneuploidy Paradox: In the Light of Evolution
Authors: Salmina Kristine , Huna Anda , Kalejs Martins , Pjanova Dace , Scherthan Harry , Cragg Mark S. , Erenpreisa Jekaterina
Published: January 2019

Aneuploidy should compromise cellular proliferation but paradoxically favours tumour progression and poor prognosis. Here, we consider this paradox in terms of our most recent observations of chemo/radio-resistant cells undergoing reversible polyploidy. The latter perform the segregation of two parental groups of end-to-end linked dyads by pseudo-mitosis creating tetraploid cells through a dysfunctional spindle. This is followed by autokaryogamy and a homologous pairing preceding a bi-looped endo-prophase. The associated RAD51 and DMC1/γ-H2AX double-strand break repair foci are tandemly situated on the AURKB/REC8/kinetochore doublets along replicated chromosome loops, indicative of recombination events. MOS-associated REC8-positive peri-nucleolar centromere cluster organises a monopolar spindle. The process is completed by reduction divisions (bi-polar or by radial cytotomy including pedogamic exchanges) and by the release of secondary cells and/or the formation of an embryoid. Together this process preserves genomic integrity and chromosome pairing, while tolerating aneuploidy by by-passing the mitotic spindle checkpoint. Concurrently, it reduces the chromosome number and facilitates recombination that decreases the mutation load of aneuploidy and lethality in the chemo-resistant tumour cells. This cancer life-cycle has parallels both within the cycling polyploidy of the asexual life cycles of ancient unicellular protists and cleavage embryos of early multicellulars, supporting the atavistic theory of cancer.
Cannabisin F from Hemp (Cannabis sativa) Seed Suppresses Lipopolysaccharide-Induced Inflammatory Responses in BV2 Microglia as SIRT1 Modulator
Authors: Wang Shanshan , Luo Qian , Fan Peihong
Published: January 2019

Hemp seed (Fructus cannabis) is rich in lignanamides, and initial biological screening tests showed their potential anti-inflammatory and anti-oxidative capacity. This study investigated the possible effects and underlying mechanism of cannabisin F, a hempseed lignanamide, against inflammatory response and oxidative stress in lipopolysaccharide (LPS)-stimulated BV2 microglia cells. Cannabisin F suppressed the production and the mRNA levels of pro-inflammatory mediators such as interleukin 6 (IL-6) and tumor necrosis factor α (TNF-α) in a concentration-dependent manner in LPS-stimulated BV2 microglia cell. Furthermore, cannabisin F enhanced SIRT1 expression and blocked LPS-induced NF-κB (Nuclear factor kappa B) signaling pathway activation by inhibiting phosphorylation of IκBα (Inhibit proteins of nuclear factor kappaB) and NF-κB p65. And the SIRT1 inhibitor EX527 significantly inhibited the effect of cannabisin F on pro-inflammatory cytokines production, suggesting that the anti-inflammatory effects of cannabisin F are SIRT1-dependent. In addition, cannabisin F reduced the production of cellular reactive oxygen species (ROS) and promoted the expression of Nrf2 (Nuclear factor erythroid-2 related factor 2) and HO-1 (Heme Oxygenase-1), suggesting that the anti-oxidative effects of cannabisin F are related to Nrf2 signaling pathway. Collectively, these results suggest that the neuro-protection effect of cannabisin F against LPS-induced inflammatory response and oxidative stress in BV2 microglia cells involves the SIRT1/NF-κB and Nrf2 pathway.
Moderate Physical Activity as a Prevention Method for Knee Osteoarthritis and the Role of Synoviocytes as Biological Key
Authors: Castrogiovanni Paola , Di Rosa Michelino , Ravalli Silvia , Castorina Alessandro , Guglielmino Claudia , Imbesi Rosa , Vecchio Michele , Drago Filippo , Szychlinska Marta Anna , Musumeci Giuseppe
Published: January 2019

The purpose of this study was to investigate the influence of moderate physical activity (MPA) on the expression of osteoarthritis (OA)-related (IL-1β, IL-6, TNF-α, MMP-13) and anti-inflammatory and chondroprotective (IL-4, IL-10, lubricin) biomarkers in the synovium of an OA-induced rat model. A total of 32 rats were divided into four groups: Control rats (Group 1); rats performing MPA (Group 2); anterior cruciate ligament transection (ACLT)-rats with OA (Group 3); and, ACLT-rats performing MPA (Group 4). Analyses were performed using Hematoxylin & Eosin (H&E) staining, histomorphometry and immunohistochemistry. In Group 3, OA biomarkers were significantly increased, whereas, IL-4, IL-10, and lubricin were significantly lower than in the other experimental groups. We hypothesize that MPA might partake in rescuing type B synoviocyte dysfunction at the early stages of OA, delaying the progression of the disease.