bluuebunny/crossref_metadata_2025 huggingface dataset:
Predictive Analysis of Yi-Gai-San's Multifaceted Mechanisms for Tremor-dominant Parkinson's Disease via Network Pharmacology and Molecular Docking Validation
Authors: Lin Chih-Ting , Wu Lung-Yuan , Tsai Fan-Shiu
Published: June 2024

Introduction:

Yi-Gan-San, Parkinson's disease, tremor-dominant, network pharmacology, molecular docking,
Uncaria rhynchophylla.

Methods:

We identified 75 active compounds within YGS. From these, we predicted 110 gene
targets, which exhibited a direct association with PD-DT. PPI network results highlighted core
target proteins, including TP53, SLC6A3, GAPDH, MAOB, AKT, BAX, IL6, BCL2, PKA, and
CASP3. These proteins potentially alleviate PD-DT by targeting inflammation, modulating neuronal
cell apoptosis, and regulating the dopamine system. Furthermore, GO and KEGG enrichment
analyses emphasized that YGS might influence various mechanisms, such as the apoptotic
process, mitochondrial autophagy, Age-Rage signaling, and dopaminergic and serotonergic synapses.
The core proteins from the PPI analysis were selected for the docking experiment.

Results:

The docking results demonstrated that the most stable ligand-receptor conformations
were kaempferol with CASP3 (-9.5 kcal/mol), stigmasterol with SLC6A3 (-10.5 kcal/mol), shinpterocarpin
with BCL2L1 (-9.6 kcal/mol), hirsutine with MAOB (-9.7 kcal/mol), hederagenin
with PRKACA (-9.8 kcal/mol), and yatein with GAPDH (-9.8 kcal/mol). These results provide
us with research objectives for future endeavors in extracting single compounds for drug manufacturing
or in-depth studies on drug mechanisms.

Conclusion:

From these computational findings, we suggested that YGS might mitigate PD-DT
via “multi-compounds, multi-targets, and multi-pathways.”
Multi-stimuli-responsive Hydrogels for Therapeutic Systems: An Overview on
Emerging Materials, Devices, and Drugs
Authors: Garshasbi Hamid Reza , Soleymani Sina , Naghib Seyed Morteza , Moepubi M.R.
Published: June 2024

:

The rising interest in hydrogels nowadays is due to their usefulness in physiological conditions as
multi-stimuli-responsive hydrogels. To reply to the prearranged stimuli, including chemical triggers, light,
magnetic field, electric field, ionic strength, temperature, pH, and glucose levels, dual/multi-stimuli-sensitive
gels/hydrogels display controllable variations in mechanical characteristics and swelling. Recent attention has
focused on injectable hydrogel-based drug delivery systems (DDS) because of its promise to offer regulated,
controlled, and targeted medication release to the tumor site. These technologies have great potential to improve
treatment outcomes and lessen side effects from prolonged chemotherapy exposure.
Recent Advancements in the Analyses of Natural Products
Authors: Aslan Erdem Sinem , Dogan Aysegul , Kurbanoglu Sevinc
Published: June 2024

Since ancient times, medicinal plants and their active ingredients have played a key role
in treating a wide array of ailments. Notably, in recent years, there has been a burgeoning interest
in treatments using products derived from natural sources, and some have been studied as clinical
treatments for a variety of disorders. The use of natural products to treat illness has gained increasing
scientific and public interest. Not only to ensure quality control but also to verify their efficacy
as active ingredients in various pharmaceutical formulations, the evaluation of natural products is
of paramount importance. In this field, analytical methods like spectroscopy, electrophoresis, and
chromatography are essential and are constantly being improved upon. Chromatographic techniques
are essential for determining the quality and authenticity of natural products. Moreover,
strict adherence to internationally recognized norms in validating analytical procedures guarantees
the accuracy and dependability of results. Continual research initiatives are essential for tackling
issues like adulteration and enhancing customer trust in natural products.
This review navigates through the complex field of quality control methodologies and analytical
techniques applied in evaluating plant-derived sources, which are generally used as natural
products, and focuses on the analysis of Hypericum, Curcuma, and Cannabis species.
The Model of Incremental Public Policy Development Formulation: Experimentalist Governance Approach
Authors:   Department of Public Administration Brawijaya University, East Java, Indonesia, Setyawan Dody , Sumartono Sumartono , Muluk M. R. Khairul , Amin Fadillah
Published: June 2024

This paper presents a new model for policy learning in the policy formulation process, integrating the incremental public policy development formulation model and the experimentalist governance approach. The aim of the new model is to offer a comprehensive and effective approach to addressing complex social problems. The study focuses on the activities and measures implemented by the government to control pandemic period. Through interviews, observations, and document analysis, a comprehensive understanding of the pandemic situation was achieved. The use of triangulation adds validity to the research findings, resulting in a well-rounded and reliable analysis of the crisis in the city. The results and discussion demonstrate the effectiveness of the Incremental Public Policy approach, specifically the Adjusted Plagiarism Incremental model, in responding quickly to dynamic situations such as a global pandemic. This model highlights the importance of making incremental changes to existing policies to adapt to changing circumstances. This approach proved effective in addressing the challenges pandemic period. By continuously reassessing and adjusting policies based on new information and feedback, the government successfully mitigated impact on the residents of the city in pandemic period. This flexible and adaptive approach to public policy proved crucial in navigating the uncertainties and complexities of the pandemic, emphasizing the significance of agility and innovation in crisis management.
Implementation of TPACK-based problem-based learning model on social studies learning outcomes of elementary school students
Authors: Darmawati Desak Made , Arini Novanita Whindi , Yanti Prima Gusti , Hidayati Deasy Wahyu , Amzat Ismail Hussein
Published: June 2024

This study aims to determine Social Studies (IPS) learning outcomes with a problem-based learning model based on Technological Pedagogical Content Knowledge (TPACK) in elementary school students. The research method used is descriptive quantitative with quasi-experiment. The implementation was carried out in stages with the theory of Borg and Gall, and the main stages are (1) preliminary studies in the form of preparation and needs analysis; (2) preparation of model design and prototype model products in a participatory manner; (3) analysis of trials by learning technology experts; (4) operational trials carried out repeatedly / cycles accompanied by refinement of model products; (5) validation tests using pre-experimental design; and (6) dissemination of results. Data collection in this study was done using objective tests. Observations using observation guideline instruments on activities during the operational test process and pre-experimental tests. Questionnaires and performance assessments were used in the operational and model validation tests. The observation results were analyzed descriptively quantitatively, finding the mean, median, mode, standard deviation, and variance of each variable studied. Data analysis techniques used (1) descriptive analysis, (2) requirements test analysis, and (3) hypothesis testing. The findings of the research showed that elementary school students were motivated to learn by using TPACK-based problem-based learning models and had a high understanding of using ICT learning. The analysis of research results could affect the learning outcomes of social studies based on technological pedagogical content knowledge in elementary schools with an average score of 79.42. So, this research uses classroom action research conducted in 3 (three) cycles. The results obtained up to the third cycle stage (three) were declared complete.
Exploring emotions and sentiments in the Philippine esports industry: A mixed methods approach
Authors:   College of Industrial Technology, Northern Iloilo State University, Estancia, Philippines, Derla Ronald D.
Published: June 2024

The number of participants and viewers in esports is increasing, making it a rapidly growing industry worldwide. In the Philippines, esports elicit a variety of feelings and attitudes. This paper investigates these emotions and sentiments, specifically anger, anticipation, fear, disgust, sadness, joy, surprise, and both positive and negative feelings, using existing research studies and articles. The research adopts the Exploratory Sequential Mixed Methods approach, starting with gathering and analyzing qualitative data, followed by collecting and analyzing quantitative data, and finally, integrating the findings from both data types. The study employs data cleaning techniques such as tokenization, removing URLs, stop words, special characters, and hashtags. Additionally, it uses Latent Dirichlet Allocation (LDA) to explore different topics within journal articles, online news, and various issues related to esports in the Philippines. Opinion mining and sentiment analysis are techniques used to derive meaningful subjective information from text. The findings indicate that many Filipinos hold positive views, including trust, anticipation, joy, and surprise towards the burgeoning esports sector in the country. However, a small percentage of Filipinos still express anger, disgust, fear, sadness, and negative opinions about esports. The discussion on esports in the Philippines has evolved to acknowledge its growth as an industry, its increasing popularity as a sport, and its demands for mental and physical training, among other aspects.
mHealth Apps for Hypertension Self-Management: Interview Study Among Patient-Users
Authors: Muehlensiepen Felix , Bruch Dunja , Seifert Frances , Wengemuth Eileen , Heinze Martin , Spethmann Sebastian , May Susann
Published: June 2024

Background

Hypertension is a major risk factor for cardiovascular disease, affecting over a billion people worldwide. Mobile health (mHealth) apps have emerged as effective tools for managing hypertension, offering capabilities for monitoring blood pressure, fostering lifestyle changes, and improving treatment adherence.

Objective

This study aimed to explore patient-users’ perspectives on the hypertension care mHealth app Hypertension.APP, focusing on its accessibility, expected benefits, potential risks, and role in hypertension management in Germany.

Methods

A qualitative study was conducted involving semistructured interviews with 20 patient-users of a hypertension care mHealth app, Hypertension.APP. Participants were recruited between January and June 2023 using purposive sampling. Verbatim transcripts were analyzed using qualitative content analysis.

Results

Participants primarily discovered the app independently, driven by recent hypertension diagnoses and insufficient information from health care professionals regarding effective self-management strategies for their blood pressure. They valued the app for its continuous monitoring and feedback capabilities, aiding in understanding their condition and making lifestyle adjustments. Risks were perceived as minimal, mainly concerning data privacy and potential overreliance on the app. The app became integral to patient-users’ hypertension management by offering consistent information and support. The integration into formal health care was limited, as patient-users felt that health care professionals did not accept the use of the technology or might have even felt intimidated to use it.

Conclusions

Among the sample studied, mHealth apps like Hypertension.APP were valued for their continuous monitoring and educational content, aiding in hypertension management. The findings suggest potential benefits of mHealth apps for effective hypertension care among patients who are health- and digitally literate as well as self-effective. There is a critical need for better integration of these apps into routine health care practices, as perceived by the app users. Given the small and specific sample of this qualitative study, further quantitative research with a broader and more varied participant group is necessary to validate these findings.

Trial Registration

Deutsches Register Klinischer Studien DRKS00029761; https://tinyurl.com/r33ru22s
Prevalence of Musculoskeletal Symptoms in Patients With Hidradenitis Suppurativa and Associated Factors: Cross-Sectional Study
Authors: McKee Hayley , Eder Lihi , Jerome Dana , Mirza Reza D , Obetta Chikaodili , Pek Elisabeth , Piguet Vincent , Alhusayen Raed
Published: June 2024

The prevalence of and factors associated with musculoskeletal (MSK) symptoms in patients with hidradenitis suppurativa (HS) have yet to be elucidated. Given the association between HS and inflammatory comorbidities, understanding the burden of MSK symptoms in patients with HS is crucial for patient-centered care. Our objective was to describe the prevalence of and factors associated with MSK symptoms in patients with HS. A cross-sectional study of 78 consecutive patients recruited between November 2021 and February 2023 with a dermatology-confirmed diagnosis of HS, irrespective of MSK symptoms, was performed. The average age of participants (n=78) was 37 (SD 12.2) years, and the average age at symptom onset was 23 (SD 12.1) years; 54% (n=42) of participants identified as women, and 46% (n=36) as men. The most common comorbidities included depression (n=17, 22%) and preexisting arthritis (n=12, 16%). Approximately 24% (n=18) of participants reported prolonged morning stiffness. In a multivariate regression, depression was significantly associated with morning stiffness (odds ratio [OR] 6.1, 95% CI 1.4-26.1; P=.02), while female sex was significantly associated with arthralgia (OR 19.1, 95% CI 1.6-235.2; P=.02). Every patient with depression reported arthralgia. We highlight the high prevalence of MSK symptoms among patients with HS and note the interplay between depression and MSK symptoms, with each one potentially contributing to the other.
Critical Factors for the Successful Usage of Fly Ash in Road Sectors, Analyzing Mega Projects of Pakistan
Authors: Ahmad Shakeel
Published: June 2024

Abstract: Fly Ash is known to be a hazardous material which can cause Water, Air & Soil Pollution. As per Previous study Fly Ash may be considered as a resourceful material (Alam & Akhtar, 2011; Sahay & Bansal, 2022). Twelve (12) Critical Factors are been identified, Studied, analyzed and then classified using Interpretive Structure modeling (ISM), which are presented as a model in this paper. These Critical Factors shown in Final Model is a strategic planning towards the successful usage of Fly Ash in road sectors of Pakistan. Also, MICMAC analysis will help to present managerial suggestions which is useful for stakeholders
Janu Marma: A Literary Review Co-Relation with Modern Concern
Authors: Rohila Dr. Saurabh Chandra
Published: June 2024

Abstract: The description of Marma is an important part of Ayurvedic Rachana Sharira (Anatomy). Acharya Sushruta discusses the Marma as an anatomical aspect of several bodily parts. In the human body, total marma points are 107. Janu Marma is one of them. It is a Sandhi Marma which is located at the knee joint. Several anatomical structures are connected to Janu Marma, each of which can be injured by disease or external factors, resulting in temporary or permanent impairment or loss of function. The knee joint, the body's largest and most complex synovial joint, comprises the femur, tibia and patella. It includes three subjoints: patellofemoral, lateral tibiofemoral, and medial tibiofemoral joints. This work is an attempt to provide accurate guidelines on the location, composition and structural anatomy of Janu Marma in comparison to modern science.
Optimized Logic Gate Design using QCA
Authors: Bhoi Bandan Kumar
Published: June 2024

Abstract: Quantum-dot cellular automaton (QCA) represents a burgeoning and auspicious nanoelectronic computational framework for the forthcoming generation, where binary data is encoded through the electronic charge arrangement within a cell. This architec- ture, rooted in digital logic, leverages individual electrons within arrays of quantum dots to execute binary operations. At the core of QCA circuits lies the QCA cell, serving as a fundamental unit for constructing basic gates and logic devices within QCA architectures. An assessment of diverse QCA-based XOR gate implementations is conducted in this study, alongside the proposition of novel layouts exhibiting enhanced performance metrics. The paper delves into various methodologies for designing QCA circuits, specifically focus- ing on the XOR gate. These layouts demonstrate a reduced number of crossovers and a diminished cell count in comparison to the conventional structures documented in existing literature. Notably, these design configurations hold significance for communication- centric circuit applications, particularly in activities such as phase detection within digital circuits, arithmetic computations, and error identification and rectification processes. A comparative analysis of different circuit designs is also provided, illustrating the potential of the proposed layouts in realizing more intricate circuits. The simulations in this study are executed utilizing the QCADesigner tool.
GHIRO Unveiled: A Comprehensive Approach to Image Forensics and Suspect Detection
Authors: Dodiya Kiranbhai R
Published: June 2024

Abstract: In contemporary society, the ubiquity of digital photography has engendered a paradigm shift in how individuals perceive and interact with visual information. This proliferation, however, has concurrently birthed an inherent vulnerability: the susceptibility of digital images to manipulation. The ramifications of this susceptibility extend across diverse sectors, including but not limited to public discourse, law enforcement, political narratives, and media representations. In light of the escalating sophistication of digital editing tools, the pervasiveness of counterfeit photographs has become an increasingly pressing concern, precipitating a palpable erosion of trust in the integrity of visual media. This research addresses this difficulty by propounding a methodological framework centred around Ghiro software—a commendable exemplar of open-source innovation tailored to expedite the forensic scrutiny of digital imagery. Ghiro, with its automated algorithms, operates as a stalwart sentinel in elucidating alterations perpetrated upon original photographs. Its efficacy, epitomised by a judicious amalgamation of computational prowess and forensic acumen, positions it as a formidable bulwark against the surreptitious incursions of digital manipulation. Methodologically, this study adopts an empirically grounded approach, wherein the efficacy of Ghiro in discerning subtle alterations within digital photographs is subjected to rigorous scrutiny. Ghiro's capacity to unveil an array of manipulations—ranging from pixel-level modifications to intricate compositing— is unequivocally showcased through meticulously designed experimental protocols. Notably, the study accentuates Ghiro's utility as an automated tool, thereby mitigating the temporal and cognitive burdens traditionally associated with manual forensic analysis. These findings have direct implications for professionals in the fields of digital photography, law enforcement, and media representation, providing them with a powerful tool to combat digital image manipulation.
Natural Language Processing (NLP)
Authors: G Dr. Chandrika
Published: June 2024

Abstract: Machines utilize Natural Language Processing (NLP), a subfield of Artificial Intelligence (AI), to comprehend, evaluate, and translate human languages. Due to advancements in information and communication technology over the last ten years, NLP has gained increased awareness and has been the subject of several studies. Understanding the steps required to advance literary understanding is so crucial. The study's objective is to provide an organized review of the literature in NLP research using bibliometric analysis. In the discipline of NLP, the study highlights important research fields, research clusters, cited publications, significant authors, institutions, nations, and publishing patterns. From the Web of Science (WoS) database, 12541 NLP papers were taken out and subjected to further bibliometric analysis The outcome showed that the largest number of NLP publications occurred in 2021, with the first publication being in 1989. The leading journal with the most publications was IEEE Access, and NLP papers have earned the most citations—3174—than any other journal. Liu HF is the most productive author in the field of NLP, and Harward University is the most significant organization. When it comes to the overall amount of publications, the US is the top nation. Researchers looked at the applied sciences in great detail.
Social Media and the Risk of Poor Mental Health Among Young Adults
Authors: Dave Pallav
Published: June 2024

Social media platforms have become an integral part of people’s lives in the last decade. As a prominent fixture in young people’s lives, social platforms have allowed them to share their experiences and connect with peers. However, using these platforms excessively can become problematic. Research has linked problematic use of social sites to more risk of having mental health issues. Some of the common mental health problems reported include depression, anxiety, loneliness, social media-related fatigue, unhappiness, and increased risk of alcohol use. Different reasons contribute to the increased risk of developing mental health problems because of excessive use of these platforms. They are sedentary behavior, poor sleep patterns, cyberbullying and victimization, multitasking, and internalizing online experiences. Others have a high risk of developing mental disorders because they neglect important aspects of their lives such as real-life social interactions. Addressing these factors can lower individual’s risk of developing mental health issues. Besides, some studies have shown that there is a link between using social platforms and positive mental health more so for individuals struggling with mental problems. Social sites can be used to provide social support for young individuals experiencing mental problems. Individuals can use these problems to share about their life struggles with mental issues. They can also use these platforms to obtain help and resources. Therefore, the aim of this review is to explore how social media increases the risk of mental problems among young adults.
Keywords: Social media, depression, anxiety, loneliness, social support, problematic/excessive social media use
The Distal Pole-Alternative to Conventional Distal Shoe Space Maintainer: A Case Report
Authors: Kottai Gandhi Geeth Deepika , PT Jonathan Vasantha Rajan , Gopalan Dinesh Nandakumar
Published: June 2024

Aim and Background: A major clinical challenge for pedodontist is space maintenance in primary dentition associated with the premature loss of primary teeth. When a primary second molar is lost prematurely, it is the distal shoe appliance (DSA) most widely used and proved to be the effective tool in guiding the permanent first molar into its proper place.
Case Description: The sole purpose of this case report is to describe briefly the clinical management of unilateral extensively carious primary mandibular second molar with a modified distal shoe space maintainer which we named it as “distal pole” which is highly inevitable to prevent space loss and following malocclusion development in later stages.
Clinical Significance: The prime importance in pediatric dentistry is preserving the primary teeth in the dental arch until their physiological exfoliation time however there are certain conditions which are challenging at times where extraction seems unavoidable.
Keywords: distal shoe, space maintenance, E space, Deciduous Dentitions
Factors Contributing to Sleep Disorders Among Young Adults
Authors: Dave Pallav
Published: June 2024

Sleep disorders are increasingly being reported among young adults. The recent Gallup Survey is an indication of the magnitude of the problem more so among young Americans. Sleep is important for good health and well-being. Different studies have shown the negative effects of sleep disorders on overall health and well-being. Sleep deprivation and disorders increase the risk of depression and anxiety. It also increases the risk of diabetes, obesity, hypertension, and heart attack. Sleep disorders occur because of a number of factors including psychosocial stressors, chronic pain, caffeine intake, smoking, lack of physical activity, poor sleep environment, use of screens before bedtime, and alcohol consumption. These factors are prevalent among the youth which explains the increased risk of sleep disorders in this population. Addressing sleep disorders is vital because they are associated with poor functioning. Individuals who report sleep disorders tend to have lower work productivity, increased risk of accidents, and poor health. Lifestyle modifications can help to address the growing problem of sleep disorders among young adults.
keywords: Sleep disorders, insomnia, obstructive sleep apnea, sleep deprivation, daytime sleepiness
Portable Dental Chair Innovation in Improving Operator Comfort
Authors: Putri Rindharso Rahmaisynta , Santoso Bedjo , Sunarjo Lanny , Aryati Eko Ningtyas Endah
Published: June 2024

Objective: to produce a suitable portable dental chair innovation and its effective application in improving operator comfort.
Materials and Methods: This study was an R&D type with a pre-experimental design. Sampling was done using purposive sampling with a total of 30 Dental Therapists across all primary health centers in the Banjarbaru City. The independent variable was the Portable Dental Chair innovation, and the dependent variable was operator comfort.
Results: The use of portable dental chair innovation provides convenience in dental health services regarding operator comfort, which is sometimes suboptimal, as well as limitations in features for complex dental care. Technical and logistical issues such as equipment damage and lack of resource availability can also be challenging. Therefore, innovation in the production of portable dental chairs is crucial. Technological advancements can improve ergonomics, efficiency, and equipment quality, addressing the increasing market demand for mobile and flexible dental care. Thus, this innovation not only provides solutions to existing problems but also expands access to quality dental care for more people, resulting in a positive impact on overall dental health sector.
Conclusion: Portable Dental Chair Innovation is suitable and effectively applied to improve operator comfort.
Keywords: Dental Therapists, Portable Dental Chair, operator comfort
O CINEMA COMO FERRAMENTA PEDAGÓGICA MULTIMODAL NO ENSINO DE CIÊNCIAS E BIOLOGIA
Authors: Bastos Raquel Ribeiro de Carvalho , Frasson Fernanda , Zompero Andreia de Freitas
Published: June 2024

Este trabalho de cunho teórico propõe uma leitura integrada entre os referenciais da Multimodalidade Representacional e do Cinema, discutindo suas contribuições como ferramenta pedagógica no ensino de Ciências e Biologia. Os problemas centrais examinados são como a integração de múltiplos modos de representação no Cinema, facilitada pelo sincretismo semiótico, pode melhorar a compreensão dos alunos em conceitos científicos complexos, e também como essa integração pode melhorar o engajamento dos alunos na aprendizagem de tais conceitos. Utilizou-se uma metodologia de revisão integrativa da literatura para analisar estudos sobre Multimodalidade Representacional e Cinema. Conclui-se que o Cinema, ao combinar elementos visuais, auditivos e textuais, oferece uma plataforma dinâmica para a aprendizagem, superando as limitações das abordagens tradicionais. A integração das teorias de Multimodalidade Representacional e Cinema proporciona uma abordagem inovadora e relevante para a educação científica. Diante da leitura realizada, conclui-se que o Cinema é uma ferramenta pedagógica multimodal com grande potencial para a promoção da aprendizagem em alunos de Ciências e Biologia.
Knowledge flows for rural producers: evidence from the Medellín ecosystem, Colombia
Authors: Coletto Camila , Caliari Leonardo , Bernardes de Souza Dércio , Callegaro de Menezes Daniela
Published: June 2024

This study aims to analyze how knowledge flows occur between rural producers and the ecosystem of Medellín. Based on the case study method, 26 interviews were carried out, encompassing 10 rural producers and 16 actors of the ecosystem of Medellín, besides the documental analysis and direct observation, to complement the triangulation of the evidence sources. In the results, it was possible to map knowledge flows, identifying the actors of the ecosystem that interact with the rural producers of low technological incorporation. The University of Antioquia stands out with projects that involve producers in defining the demands to be met, but these are individualized actions on the part of the university, requiring greater integration of the other players in the ecosystem. The present study contributes with knowledge regarding a flow model to be replicated, in which a framework can be structured, to be investigated in other ecosystems, as well as its interactions with productive chains.
Hubungan Pola Makan dan Stress terhadap Kejadian Gastritis di Ruang Rawat Inap Penyakit Dalam
Authors: Sylvia Elsa , Suwahyu Romy
Published: June 2024

Gastritis is an inflammation of the gastric mucosa. Gastritis can be caused by diet, drugs, alcohol, bacterial infections, stress conditions, illness. Gastritis occurs in people who have an irregular diet and eat foods that stimulate the production of stomach acid. Workload and life problems (stress) can trigger gastritis. The aim of the study was to know the relationship between diet and stress on the incidence of gastritis in the internal medicine ward of Bhayangkara Hospital. The research design was cross sectional with purposive sampling technique. The population was 100 people and the sample size was 35 people. Place of research in the internal medicine ward of Bhayangkara hospital. The study was conducted in February 2023. The univariate results were 54.3% with acute gastritis, 60.0% with a good diet and 60.0% with mild stress. The bivariate results showed that there was a relationship between diet and stress with the incidence of gastritis, the p value of the two variables was 0.00. Suggestions for the hospital can provide education about a good diet, as well as provide counseling services for people with gastritis (as needed).
Abstrak
Gastritis adalah suatu peradangan mukosa lambung. Penyakit gastritis dapat disebabkan karena pola makan, obat-obatan, alkohol, infeksi bakteri, kondisi stres, penyakit. Penyakit gastritis terjadi pada orang-orang yang mempunyai pola makan yang tidak teratur dan memakan makanan yang merangsang produksi asam lambung. Beban kerja dan persoalan hidup (stres) dapat memicu terjadi gastritis. Tujuan penelitian adalah diketahuinya hubungan antara pola makan dan stres pada kejadian gastritis di ruang rawat inap penyakit dalam Rumah sakit Bhayangkara Palembang. Rancangan penelitian adalah cross sectional dengan tehnik pengambilan sample purposive sampling. Populasi 100 orang dan jumlah sampel 35 orang. Tempat penelitian di ruang rawat penyakit dalam Rumah sakit Bhayangkara Palembang. Penelitian dilakukan bulan Februari 2023. Hasil penelitian univariat didapatkan 54,3% dengan gastritis akut, 60,0% dengan pola makan baik dan 60,0 % dengan stres ringan. Hasil bivariat didapatkan ada hubungan pola makan dan stres dengan kejadian gastritis, nilai p value kedua variable adalah 0,00. Saran bagi Rumah sakit dapat memberikan edukasi mengenai pola makan yang baik, serta menyediakan layanan konseling untuk penderita gastritis (sesuai kebutuhan).
Kata kunci : Gastritis, pola makan, stress
La evolución logística en las empresas
Authors: Cely-Cely Viviana Marcela , Carrillo-Estrada Maryurie Dayana , Rolón-Rodríguez Blanca Mery
Published: June 2024

Al transcurrir de los años, la logística ha evolucionado innovando lo relacionado con los procesos, productos, entrega de mercancía, formas de pago y almacenamiento de información. Todo esto hace necesario que las empresas o aquellas personas que planean crear empresas tengan en cuenta la necesidad de incorporar en sus negocios alguno de los tipos de logística que hoy en día son tendencia ya que estos permiten el desarrollo, crecimiento y avance de las empresas. Cabe resaltar la importancia de que esto debe convertirse en una necesidad en las empresas pues gracias a estos métodos, las empresas han logrado avanzar a través del tiempo y mantenerse en el mercado generando nuevas oportunidades de empleo. Algunas de las tendencias más relevantes incluyen: la automatización de procesos la cual disminuye la posibilidad de errores, el monitoreo que ayuda a tener un control y seguimiento ya sea de productos o de clientes, la última milla lo cual hace referencia al último momento en el cual la mercancía llega a manos del cliente, las entregas rápidas que como su nombre lo indica permite mayor rapidez en la entrega de productos, la logística verde que hace referencia a que tanto los productos como la forma de entrega sea eco-amigable, la inteligencia artificial que brinda herramientas tecnológicas para facilitar cualquier tarea, los drones y los camiones autónomos que se encargan de realizar entregas directamente a los clientes, los cambios en las formas de pago ya que se hacen a través de plataformas de forma más rápida y desde cualquier parte del mundo, y el almacenamiento en la nube que fue el boom durante la pandemia y gracias al cual muchas empresas lograron implementarlo.
Análisis de la Influencia de Costos en la Productividad de las Zonas Cafetaleras de Colombia
Authors: Rey- cevedo Laura Micheli
Published: June 2024

La producción en las empresas agrícolas del país es importante porque de ellas depende gran cantidad de abastecimiento de los principales rubros de la economía y el desarrollo de la mano de obra especializada para tal fin; de allí que los costos de producción son un punto clave en el desarrollo de las contabilidades de las empresas, más el área cafetalera que requiere de análisis de costos a profundidad para poder evaluar la rentabilidad de la industrialización, conocimiento de los costos variables, costos fijos y gastos en general, que incluyen mano de obra, insumos del agro, proyecciones e inversiones a corto/mediano y largo plazo. El objetivo general que se presenta es: Analizar la influencia de costos en la productividad de las zonas cafetaleras de Colombia. Se aplicó una metodología de análisis descriptivo sobre la consulta de 50 referencias de diversos trabajos publicados de tesis, libros y revistas científicas. Se concluyó que, es necesario establecer una relación de costos en productividad en la zona cafetalera, para poder conocer cuáles son las expectativas que enfrenta la empresa productora y que le permita establecer un margen de utilidad, calculando el costo preciso por kilogramo del producto, para ello han de establecerse análisis profundos, aproximaciones con costos históricos, establecimientos comparativos de precios, factores intervinientes del costos, como son los costos fijos/variables, los cuales son fundamentales para poder tener una base sólida en la rentabilidad del rubro.
Perlindungan Hukum Bagi Korban Pemerkosaan Sedarah yang Melakukan Aborsi Ditinjau dari Hak Asasi Perempuan
Authors: Gita Yunita Eka , Ulum Mukhamad Bahrul
Published: June 2024

This research aims to identify cases of rape victims committed by blood parties where the victim has experienced pregnancy and followed by abortion, this research will be reviewed through Women's Human Rights. Women are entitled to receive justice and legal protection by the government. Abortion or better known by its legal term, abortus procatus which in Latin has the meaning and meaning of deliberate abortion of the womb. Abortion is one of the many health cases that claim many victims, abortion is also one of the health cases included in the criminal act. Criminal regulation of abortion is not without reason, this is done one of them with the aim of saving women's health. Departing from one of the cases that occurred in the community, especially in Batang hari district, where the victim was raped by her own biological brother to experience pregnancy and abortion. The research method used in this study uses normative research using legal norms using a case approach. The results can be concluded that all forms of legal provisions regarding abortion, stating that the act of abortion is not allowed unless there are certain indications that allow it. So that there needs to be legal corrective action related to abortion, especially in certain conditions in order to create a sense of security and justice for others.
Sertifikasi Elsimil Bagi Calon Pengantin Sebagai Salah Satu Syarat Administrasi Pernikahan Ditinjau Dari Maṣlaḥah Mursalah
Authors: Son Haji Saputra  , Seno Aris Sasmito
Published: June 2024

The elsimil certification programme (siap nikah dan siap hamil) is an electronic application-based nutrition screening programme and premarital health assistance for prospective brides and grooms which is intended as an effort to help plan the formation of a healthy, quality family, ready for marriage and especially ready for pregnancy. The purpose of this study is to determine the implementation of elsimil certification for prospective brides as one of the requirements for marriage administration in Ngawi District, Ngawi Regency in 2023 with a review of maṣlaḥah mursalah. The research method used is qualitative field method, with data collection techniques including interviews, observation, and documentation. The results showed that the implementation of elsimil certification in Ngawi District, Ngawi Regency, is not fixed on the rules that require 3 months of assistance before marriage, because for those whose marriage registration is too tight, elsimil certification assistance can be proposed after marriage. So, the bride-to-be can still get married according to the planned time and certainly does not complicate the marriage. The benefit contained in the elsimil certification is ḥājiyyāt because it can avoid difficulties in the framework of ḥifẓu an-nasl.
Tantangan Dan Peluang Eksistensi Asuransi Syariah Pada Era Digital Dan Upaya Pengembangannya Di Indonesia
Authors: Wendy Dika Ariani  , Fairuz Sabiq
Published: June 2024

This research aims to analyze challenges and opportunities of sharia insurance in the digital era as well as efforts to develop sharia insurance in Indonesia. This research uses descriptive analysis with a qualitative approach. The discussion in this article is a literature review based on literature references. The results show that based on the Fatwa of the National Sharia Council (DSN) of the Indonesian Ulema Council (MUI) Number 21/DSN-MUI/IV/2001 sharia insurance is an effort to mutually protect and help a number of people through investment in the form of assets which provides return patterns to face certain risks through sharia-compliant contracts. The development of sharia insurance in Indonesia is quite good and significant with the use of sharia fintech digital technology. With this digital business, the opportunity to reach the wider community becomes easier. However, the challenge is that public knowledge in operating sharia fintech is still minimal. As an effort to develop it, all parties must work hard to introduce and socialize the sharia insurance system in Indonesia by educating the public in operating sharia fintech.
Penanganan Perkara Penyalahgunaan Narkotika Dengan Pendekatan Keadilan Restoratif Perspektif Hukum Pidana Islam
Authors: Avivah Firisqi Leksono  , Fery Dona
Published: June 2024

The significant increase in narcotics criminal cases in the city of Surakarta in the last three years and the situation of overcapacity in the Surakarta Detention Center have prompted the Surakarta District Prosecutor's Office to take action to resolve alternative criminal cases, namely restorative justice. Based on this background, this paper aims to examine how narcotics abuse cases are handled using a restorative justice approach at the Surakarta District Prosecutor's Office and how it is viewed from the Islamic Criminal Law perspective. This research is a qualitative field research with an empirical juridical approach. Primary data was obtained directly from the Surakarta District Prosecutor's Office in the form of case data and interviews, while secondary data was obtained from books, journal articles and scientific works related to research. To collect the data, interviews and documentation were carried out. The data obtained was then analyzed using the data analysis method according to Miles and Huberman, namely data reduction, data display, and data conclusion. The results of the research explain that the handling of narcotics abuse cases with restorative justice at the Surakarta District Prosecutor's Office has been successfully implemented in two narcotics abuse cases. Meanwhile, from the perspective of Islamic criminal law, the provisions for handling narcotics abuse cases with restorative justice are not found in the Al-Quran or Sunnah, so that the Authorities are responsible for deciding the punishment that is deemed appropriate for the case, which is usually called ta'zir.
Penggunaan Batok Kelapa sebagai Alat Tukar ditinjau dari Teori ‘Urf dan Undang-Undang No.7/2011
Authors: Safitri Novita Dwi , Andi Wicaksono
Published: June 2024

This research aims to analyze the practice of using coconut shells as a medium of exchange in buying and selling at Bahulak Market, Karungan, Plupuh, Sragen from the perspective of 'urf. This research methodology uses a type of field research with a descriptive qualitative approach. The data sources used are primary data and secondary data. The research site is Bahulak Market, Karungan Village, Plupuh District, Sragen Regency. By using data collection techniques in the form of observation, interviews and documentation. The result of this research is the practice of buying and selling is in accordance with the pillars and conditions of buying and selling according to sharia with a medium of exchange in the form of coconut shell. This coconut shell meets the criteria of a medium of exchange. From the perspective of ‘urf, this buying and selling is included in al-‘urf as-ṣaḥīḥ, al-‘urf al-‘amalī, and al-‘urf al-khāṣ which can be used as a legal basis. This buying and selling practice does not violate Law No. 7/2011 on Currency because coconut shells can only be used as a medium of exchange and cannot be considered money or currency.
Multi-scale Edge Aggregation Mesh-graph-network for Character Secondary Motion
Authors: Wang Tianyi , Liu Shiguang
Published: June 2024

As an enhancement to skinning-based animations, light-weight secondary
motion method for 3D characters are widely demanded in many application
scenarios. To address the dependence of data-driven methods on ground
truth data, we propose a self-supervised training strategy that is free
of ground truth data for the first time in this domain. Specifically, we
construct a self-supervised training framework by modeling the implicit
integration problem with steps as an optimization problem based on
physical energy terms. Furthermore, we introduce a multi-scale edge
aggregation mesh-graph block (MSEA-MG Block), which significantly
enhances the network performance. This enables our model to make vivid
predictions of secondary motion for 3D characters with arbitrary
structures. Empirical experiments indicate that our method, without
requiring ground truth data for model training, achieves comparable or
even superior performance quantitatively and qualitatively compared to
state-of-the-art data-driven approaches in the field.
Crowd Evacuation Simulation Based on Hierarchical Agent Model and Physics-based Character Control
Authors: Ye Jianming , Liu Zhen , liu tingting , Wu Yanhui , Wang Yuanyi
Published: June 2024

Crowd evacuation has gained increasing attention in recent years. The
agent-based method has shown a superior capability to simulate complex
behaviors during crowd evacuation simulation. For agent modeling, most
existing methods only consider the decision process but ignore the
detailed physical motion. In this paper, we propose a hierarchical
framework for crowd evacuation simulation, which combines the agent
decision model with the agent motion model. In the decision model, we
integrate emotional contagion and scene information to determine global
path planning and local collision avoidance. In the motion model, we
introduce a physics-based character control method and control agent
motion using deep reinforcement learning. Based on the decision
strategy, the decision model can use a signal to the motion model to
control the agent motion. Compared with existing methods, our framework
can simulate physical interactions between agents and the environment.
The results of crowd evacuation simulation demonstrated that our
framework can simulate crowd evacuation with physical fidelity.
Facial Action Units Detection Using Temporal Context and Feature Reassignment
Authors: Yang Sipeng , Huang Hongyu , Huang Ying Sophie , Jin Xiaogang
Published: June 2024

Facial action units (AUs) encode the activations of facial muscle
groups, playing a crucial role in expression analysis and facial
animation. However, current deep learning AU detection methods primarily
focus on single-image analysis, which limits the exploitation of rich
temporal context for robust outcomes. Moreover, the scale of available
datasets remains limited, leading models trained on these datasets to
tend to suffer from overfitting issues. This paper proposes a novel AU
detection method integrating spatial and temporal data with
inter-subject feature reassignment for accurate and robust AU
predictions. Our method first extracts regional features from facial
images. Then, to effectively capture both the temporal context and
identity-independent features, we introduce a Temporal feature
Combination and Feature Reassignment (TC&FR) module, which transforms
single-image features into a cohesive temporal sequence and fuses
features across multiple subjects. This transformation encourages the
model to utilize identity-independent features and temporal context,
thus ensuring robust prediction outcomes. Experimental results
demonstrate the enhancements brought by the proposed modules and the
state-of-the-art (SOTA) results achieved by our method.
Enhancing Doctor-Patient Communication in Surgical Explanations: Designing Effective Facial Expressions and Gestures for Animated Physician Characters
Authors: Kim Hwang Youn , Ali Ghazanfar , Hwang Jae-In
Published: June 2024

Paying close attention to facial expressions, gestures, and
communication techniques is essential when creating animated physician
characters that are realistic and captivating when describing surgical
procedures. This paper emphasizes the integration of appropriate
emotions, co-speech gestures when medical experts explain the medical
procedure, and designing animated characters. We can achieve healthy
doctor-patient relationships and improvement of patients’ understanding
by depicting these components truthfully. We suggest two critical
approaches to developing virtual medical experts by incorporating these
elements. First, doctors can generate the contents of the surgical
procedure with a virtual doctor. Second, patients can listen to the
surgical procedure described by the virtual doctor and ask if they have
any questions. Our system helps patients by considering their psychology
and adding medical professionals’ opinions. These improvements ensure
the animated virtual agent is comforting, reassuring, and emotionally
supportive. Through a user study, we evaluated our hypothesis and gained
insight into improvements.