bluuebunny/crossref_metadata_2025 huggingface dataset:
Sporadic and familial types of medullary thyroid carcinoma
Authors: Ilyin A. A. , Rumyantsev P. O. , Isayev P. A. , Medvedev V. S. , Vtyurin B. M. , Drozdovsky B Ya , Garbuzov P. I.
Published: October 2019

This article focuses on sporadic and familial variants of medullary thyroid cancer.
The effectiveness of Altiazem PP in patients with non-insulin-dependent diabetes mellitus in combination with mild and moderate arterial hypertension according to daily blood pressure monitoring
Authors: Ametov A. S. , Gubina E. V.
Published: October 2019

Althiazem РР is a selective blocker of slow calcium channels belonging to long-acting benzodiazepines, used for treating arterial hypertension. The efficacy and tolerance of 3-month monotherapy with althiazem PP in a daily dose of 180-360 mg was studied in 20 patients with non-insulin-dependent diabetes mellitus (NIDDM) combined with mild and moderate arterial hypertension. Acute drug test with daily arterial pressure (AP) monitoring showed that the number of the drug doses was determined by the severity of arterial hypertension and the circadian rhythm (r^0.68 and r—0.83, respectively). Daily monitoring of AP showed a significant decrease in the mean 24-h, mean daily, and mean nightly AP values. Diastolic AP normalized in 75%opatients and decreased by 10 mm Hg and more in 25%. "Pressure loading” in the daytime and at night decreased by 29.1 and 31.3%o, respectively. Increased variability of systolic AP for 24-h period decreased by 12.5%) during awakening hours and by 9.8% during sleeping. Heart rate virtually did not change. The drug exerted no negative effects on normal biphasic AP rhythm. Althiazem PP decreased the morning APpeak without notably changing the extent and rate of AP rises during the early morning hours. The drug had no negative effects on carbohydrate and lipid metabolism. Althiazem PP therapy had to be discontinued in only one female patient because of strong headaches. These data confirm high efficacy and good tolerance of althiazem PP as monotherapy for arterial hypertension in patients with NIDDM.
FRAGILIDADE AMBIENTAL E DINÂMICA GEOSSISTÊMICA: MAPEAMENTO DA PAISAGEM NA BACIA HIDROGRÁFICA DO RIO LOURENÇO VELHO, SUL DO ESTADO DE MINAS GERAIS-BRASIL
Authors: Oliveira Thomaz Alvisi de , Viadana Adler Guilherme , Pereira Allan Arantes
Published: October 2019

O arranjo e organização dos mosaicos de paisagem, revelados à superfície como unidades dinâmicas concentradoras de fluxos de matéria e energia, obedecem a uma ordem de classificação definida por homogeneidades e heterogeneidades. Nas bacias hidrográficas, consideradas por lei quando do desenvolvimento de estudos de impactos ambientais, esses mosaicos expõem a relação sistêmica existente nos terrenos compreendidos por divisores topográficos sob a influência de um canal de drenagem principal e seus tributários. Esse trabalho investigou a dinâmica das unidades de paisagem na bacia hidrográfica do rio Lourenço Velho, importante referência físico-geográfica do sul do estado de Minas Gerais, utilizando a concepção geossistêmica associada à fragilidade ambiental, em duas escalas hierarquizadas de análise. A compartimentação geomorfológica e a fragilidade ambiental nortearam a classificação das unidades geossistêmicas hierarquicamente superiores e inferiores, respectivamente, e são apresentadas aqui em documento cartográfico único, contendo também, o posicionamento da paisagem em cena. Os resultados sintetizaram a relevância da fragilidade ambiental quando utilizada na investigação da dinâmica das unidades geossistêmicas de paisagem diante da substituição do quadro natural pela inserção do uso antrópico e servem como balizadores de trabalhos futuros que estejam ajustados ao planejamento do território e à gestão dos recursos hídricos.
The Ambiguities of Iconic Design: Mo Modern Art Museum by Daniel Libeskind
Authors: Almantas Samalavičius
Published: October 2019

The article is focused on the cultural phenomena of architectural iconism that has become globally widespread due to the continuous pressure of ongoing economic, ideological and cultural globalisation and the reigning interests of the web of building industry that appropriates architectural design for its own financial purposes as well as local political stakeholders who often seek to replicate the success of previous internationally renowned iconic buildings by aspiring to the status of world-class cities. While discussing the global and local cultural contexts in which the so-called ‘Bilbao effect’ triggered the current pursuit of iconic buildings, the author of the article analyses the much publicized recent example of iconic architecture in Eastern Europe – the MO Modern Art Museum that was designed by Daniel Libeskind and opened in Vilnius, the capital of Lithuania in 2018 on the site of an abandoned and eventually demolished cinema in the vicinity of the historical Old Quarters. It is argued that despite of publicity and largely overcooked praises of international architectural media, the museum’s architectural design remains an example of ‘signatory architecture’ that largely ignores the aesthetics of its local urban environment and peculiarities of local historical and cultural context. It is suggested that that despite of claims of being contextual, in fact the building is not and on the contrary: it exhibits most of the aesthetics features that plaque iconic buildings in various localities on different continents.
The Innovation of Glassfiber Reinforced Cement (GRC) Application in Buildings
Authors: Indraswara Mohammad Sahid , A'isyah A. , Firmandhani Satriya Wahyu
Published: October 2019

One example of the innovation in building construction that is expansively used at present is Glassfiber Reinforced Cement (GRC). GRC is a cement product based on material mixed with fiberglass. GRC is one of the developments of concrete. This product easily and efficiently provides solutions to a variety of building designs. Additionally, its various forms can be applied to numerous types and functions of buildings. This research aimed to identify the suitability of GRC for several functions. The methods in this study employed a type of qualitative research, with data collection techniques in the form of observation and documentation in several examples of buildings that applied the GRC material innovation. Data analysis was obtained from observation related to GRC types, sizes, installation techniques, and functions in the building. Results showed that the GRC had various types, shapes, and sizes. It could be applied to the building exterior or interior. Each building used different GRC specifications tailored to meet needs and design of the building. GRC installation techniques could use the frame or without frames, adapted to the needs and types of GRC used
Identification of Roof Shapes that Suitable for Buildings on Bangunharjo Street Corridor According to Public Perception
Authors: Satriani Anashia Merliana , Winandari Maria Immaculata Ririk
Published: October 2019

Physical elements are the most easily observed and give visual impression that can absorbed by human memory. Physical element is formed by row of façade elements. Roof is the one of façade elements that very dominant form character. Bangunharjo is a corridor that dominant by residental functions in Semarang, Indonesia. Commercial demands and land efficiency make change to façade. Some of these changes adjust according to the perceptions of designers and buiding owners. But, the suitability of building and shape of façade elements must be assessed according to public perceptions. This study aims to find the shape of façade elements, especially roofs which suitable for Bangunharjo street corridor according public perception.The method of discussion is a quantitative method with a visual perception approach. For the result of the analysis it was found that the roof shape that most suitable for buildings on Bangunharjo is pelana (saddle roof) and limasan (pyramid roof).
Total Coliform Sumber Air Bersih dan Sistem Distribusi Air bersih Rumah Sakit Umum Daerah Ungaran Kabupaten Semarang
Authors: Sari Jasmine Purnama , Rahardjo Mursid , Joko Tri
Published: October 2019

RSUD Ungaran menggunakan sumur bor dalam memperoleh air bersih. Total coliform yang terkandung pada sumber air, bak penampung dan ruang Gizi adalah lebih dari 200 CFU/100 ml. Penelitian ini bertujuan untuk mendeskripsikan sumber, sistem distribusi serta efektivitas desinfeksi air bersih. Populasi objek adalah seluruh air bersih RSUD Ungaran, dengan sampel adalah air sumur, bak penampung dan air bersih yang keluar dari kran. Variabel dependen adalah total coliform pada air bersih dan variabel independen adalah kualitas dan kuantitas sumber air, kualitas jaringan distribusi dan dosis desinfektan dengan variabel pengganggu adalah pH dan suhu. Rata-rata pasokan air bersih RSUD Ungaran adalah 2.79 liter/detik. Kapasitas tempat tidur sebanyak 187 dengan kebutuhan 566 liter/tempat tidur/hari. Kebutuhan air bersih rumah sakit 2.48 liter/detik. Kebocoran pipa sering terjadi sehingga menyebabkan bahan pencemar seperti bakteri coliform akibat rembesan septic tank yang berjarak <10 m dengan pipa masuk kedalam air. Penambahan Kalsium Hipoklorit Ca(ClO)2 dosis 10, 15, 20, 25, dan 30 mg/l dengan waktu kontak 30 menit mampu menurunkan total coliform sebesar 98.5% yaitu jumlah rata – rata MPN Coliform kurang dari 3 atau disebut tidak terdapat pertumbuhan mikroorganisme.
Comprehensive characterization and resolution of discrepant spectrophotometric bilirubin results in patients on eltrombopag therapy
Authors: Cheng Timothy H.T. , Tsui Teresa K.C. , Kwok Jeffrey S.S. , Lit Lydia C.W. , Wong Elaine Y.L. , Kam Richard K.T. , Grote-Koska Denis , Staaden Antje , Okada Hitoshi , Fuke Noriko , Wong Raymond S.M. , Li Chi-Kong , Chan Michael H.M.
Published: October 2019

Background

Eltrombopag is a thrombopoietin receptor agonist used for the treatment of thrombocytopenic conditions. It can cause pH-dependent discoloration of plasma/serum. Eltrombopag is potentially hepatotoxic. It can affect the assessment of hyperbilirubinemia because of its (i) absorbance at ~450 nm (bilirubin), (ii) absorbance at ~550 nm (diazo-bilirubin) and (iii) it can cause yellowish discoloration of the eyes at normal circulating bilirubin levels.

Methods

We collected 66 samples from patients on a range of eltrombopag dosages up to 150 mg daily. Bilirubin was measured using multiple routine spectrophotometric analyzers, the Doumas reference method and high-performance liquid chromatography (HPLC). Plasma/serum eltrombopag concentrations were determined using liquid chromatography tandem mass spectrometry (LC-MS/MS). Spike-in and admixture experiments delineated the effects of eltrombopag and its metabolites.

Results

Forty-nine of 52 samples from patients on ≥50 mg daily eltrombopag therapy showed significantly discrepant inter-analyzer total bilirubin results, a difference up to 64 μmol/L (3.7 mg/dL). In one sample, total bilirubin varied from 8 to 65 μmol/L (0.4–3.8 mg/dL) by different routine analyzers, with direct bilirubin ≤4 μmol/L (0.2 mg/dL). There was a positive correlation between total bilirubin difference and plasma eltrombopag concentration (r = 0.679), and spike-in experiments demonstrated that Beckman AU and Doumas reference methods were susceptible to positive interference. HPLC can quantify bilirubin after separating eltrombopag, and results suggest different analyzers are affected to varying degrees by eltrombopag and its metabolites.

Conclusions

Eltrombopag and its metabolites can cause positive interference to the spectrophotometric measurements of total bilirubin. Accurate measurements of total bilirubin may improve our understanding of the prevalence of hyperbilirubinemia in patients on eltrombopag therapy.
Desorption of hydrolyzed poly(AM/DMDAAC) from bentonite and its decomposition in saltwater under high temperatures
Authors: Lin Ling , Li Xin , Shi Chenliang , Mao Yifan
Published: October 2019

Under harsh conditions, the desorption of polyampholytes from bentonite (Bent) can affect the performance of drilling fluids. To study the desorption of polyampholyte from bentonite, partially hydrolyzed copolymers of acrylamide and diallyl dimethyl ammonium chloride (HPAD), containing carboxyl groups, quaternary ammonium groups and amide groups was synthesized via free radical copolymerization followed by hydrolyzation. The molecular structure of HPAD was characterized by1H NMR and13C NMR. The adsorption equilibrium of HPAD on Bent in the presence of 10 wt% NaCl was 106 mg·g–1. The adsorption-desorption behavior of HPAD on Bent was studied using a high pressure and high temperature (HPHT) filtration apparatus, to obtain the filtrate liquid and filter cakes. The content of HPAD in the filtration and the filter cakes was determined via UV and element analysis, respectively. As the temperature increased, the desorption of HPAD from Bent accelerated owing to molecular thermal motion and thermal degradation of the adsorptive groups. Notably, the decomposition rate of the amide group was more than twice that of the quaternary ammonium group. The critical temperature for HPAD desorption was 135°C, as the decomposition of the adsorptive groups became predominant over intensified molecular thermal motion at high temperatures.
Quid Pro Quo! Organization Theoretical Remarks about FIFA’s Legitimacy Under Blatter and Infantino
Authors: Richau Lukas , Emrich Eike , Follert Florian
Published: October 2019

This article addresses the question of the legitimacy of sports organizations, with a particular focus on the football organization FIFA. By applying elements of the public choice theory as well as the concept of political machines to FIFA, we show that the FIFA leadership established an allocation system that works on a discretionary basis in addition to the formal rule-based allocation process. FIFA uses this exchange system to please selected member associations, which in return vote in favor of the leadership’s plans and secure its legitimacy. We further illustrate that such a system can only exist in the long run if the majority of both internal and external stakeholders approves the system.
Just Transition at the Intersection of Labour and Climate Justice Movements: Lessons from the Portuguese Climate Jobs Campaign
Authors: Kenfack Chrislain Eric
Published: October 2019

In the current context of climate change and its accompanying adverse effects on natural, human and social systems, the imperative of transitioning to low- and preferably post-carbon societies has become a non-negotiable reality if we want to avoid reaching the point of no return in terms of environmental and climate catastrophe. Such a transition requires that the interests and needs of workers and their communities be taken into consideration to make sure they do not bear the heaviest part of the burden in terms of loss of jobs and means of survival, and that they are prepared to face the new, post-carbon labour environment. The concept of Just Transition was coined to describe both the socio-political project put forward by trade unions in response to climate change, and the recognition by climate activists that the livelihoods and security of workers and their communities must be ensured during the transition to a post-carbon society. However, just transition movements are divided between two quite different orientations, which are labelled “affirmative” and “transformative.” On the one hand, affirmative just transition advocates envisage a transition within the current political-economic system. Transformative just transition activists, on the other hand, envisage a post-capitalist transition. This article, drawing upon an extensive case study of the Portuguese climate jobs campaign, goes beyond showing how these orientations shape the positions taken by union and climate activists. The article also analyses how the conflicts and cooperation between these key actors can shed light on the possibilities and/or limitations of just transition as a framework for the collective action needed to achieve rapid, deep decarbonisation of economies in the Global North context.

KEY WORDS: climate change; just transition; labour environmentalism; climate jobs; climate justice; climate activism
Reconsidering Osmond
Authors: Noonan Charles
Published: October 2019

Over 30 years has now passed since the High Court of Australia held in Public Service Board (NSW) v Osmond that the common law imposes no obligation on administrative decision-makers to provide reasons for their decisions. Despite this, significant developments made in Australian administrative law since Osmond was decided may in fact cause major difficulties to a rule that has survived the past 30 years largely unscathed. This paper demonstrates that although the emergence of Li unreasonableness is unlikely to give rise to a common law duty to provide reasons, the principles of natural justice provide a solid doctrinal foundation for the High Court to reconsider the position expressed in Osmond.
Electrospun Polycaprolactone for Controlled Drug Delivery
Authors: Govorčin Bajsić Emi , Zubin Ferri Tea , Tominac Trcin Mirna , Holjevac Grgurić Tamara , Mijović Budimir , Zdraveva Emilija
Published: October 2019

Tkivno inženjerstvo dobra je alternativa za razvoj tkiva ili potencijalnih organa iz pacijentova vlastitog staničnog materijala, a kako bi se smanjio problem nedostatka organa za transplantaciju. Elektroispredeni materijali su dobri kandidati kod primjene u biomedicini tj. kao nosači za uzgoj tkivnih stanica. Kod regeneracije tkiva mogu dodatno prenositi lijekove kontrolirano prema terapiji. U ovom je radu istraživano kontrolirano otpuštanje antibiotika Cefuroxima (CFU) koji se upotrebljava u terapiji okularnog tkiva. Elektroispredeni su polikaprolaktonski nosači uz dodatak CFU-a u udjelima od 1, 2, 5 i 10 mas %. Uspješna kapsulacija antibiotika potvrđena je pojavom novih karakterističnih pikova u FTIR spektrima elektroispredenih mješavina. Dodatkom antibiotika i povećanjem njegove koncentracije dobivaju se vlakna homogenijeg izgleda s manjim brojem deformacija po duljini vlakna. UV-VIS spektrofotometrijom praćeno je vrijeme otpuštanja antibiotika iz elektroispredenih PCL/CFU nosača. Dobiveno je povećanje apsorbancije antibiotika s vremenom i porastom koncentracije lijeka u nosaču.
Preparation of 3D Porous Scaffolds for Bone Tissue Engineering
Authors: Ivanković Marica , Ivanković Hrvoje , Antunović Maja , Rogina Anamarija , Ressler Antonia , Bauer Leonard
Published: October 2019

Inženjerstvo koštanog tkiva brzorastuće je polje istraživanja usmjereno na razvoj bioaktivnih 3D poroznih nosača, kao privremenih izvanstaničnih matrica, koji podržavaju prianjanje, umnažanje i diferencijaciju stanica te potiču stvaranje koštanog tkiva in vivo. Više od deset godina istraživanja naše grupe posvećena su razvoju novih materijala i postupaka za pripravu 3D poroznih nosača za inženjerstvo koštanog tkiva. Kao mogući nosači istraživani su porozni skeleti morskih organizama te kompozitni materijali i hidrogelovi na temelju biorazgradljivih polimera i bioresorbirajuće hidroksiapatitne keramike. U ovom radu dan je prikaz naših istraživanja i glavnih postignuća, objavljenih u međunarodnim znanstvenim publikacijama.
Ekstrakcija i ispitivanje stabilnosti polifenola komine masline u prirodnim eutektičkim otapalima
Authors: Mitar Anamarija , Kučić Grgić Dajana , Prlić Kardum Jasna
Published: October 2019

Polifenolni spojevi, zaostali u komini koja je nusproizvod u proizvodnji maslinova ulja, antioksidansi su koji imaju pozitivan učinak na ljudsko zdravlje. Za izdvajanje polifenola sve češće se primjenjuju prirodna eutektička otapala koje karakterizira netoksičnost, biorazgradljivost, nezapaljivost te niska cijena. U ovom radu upotrijebljeno je prirodno niskotemperaturno eutektičko otapalo (NADES) pripravljeno od triju komponenti: DL-jabučne kiseline, D-fruktoze i glicerola (MaFruGly) s različitim udjelima vode koji omogućavaju uspješnu ekstrakciju polifenola. Određena je optimalna metoda ekstrakcije, a nakon provedene ekstrakcije, ekstrakti su podvrgnuti mikrobiološkoj analizi te je praćena stabilnost izdvojenih polifenola. Istraživanje je pokazalo da su najuspješnije metode za ekstrakciju polifenola mikrovalno ultrazvučna te ekstrakcija ultrazvučnom sondom, a NADES s 30 % vode optimalno otapalo za održavanje stabilnosti polifenola.
Primjena naprednih polimernih materijala
Authors: Gilja Vanja , Hrnjak-Murgić Zlata , Peršić Ana , Kratofil Krehula Ljerka , Katančić Zvonimir
Published: October 2019

Sve intenzivniji razvoj naprednih polimernih materijala kao što su polimerne mješavine i (nano)kompoziti nude brojna inovativna rješenja za različitu upotrebu, što ima velik ekonomski značaj za plastičnu industriju i područja u kojima se primjenjuju. Napredne tehnike modificiranja polimera razvile su se gotovo do krajnjih granica, a znatno su poboljšale omjer troškova i svojstava nastalih modifikacijom strukture polimera. Miješanje različitih polimera, priprema (nano)kompozita te stvaranje višeslojnih materijala, laminata neke su od najznačajnijih tehnika modifikacije. Pri tome postoje sinergistička djelovanja između komponenti, kako bi se postigli izvrsni učinci koji su prilagođeni specifičnim primjenama, kao npr. antimikrobno djelovanje, blokiranje ultraljubičastog svjetla, smanjenje gorivosti, fotokatalitičko djelovanje, a u radu su prikazani rezultati ispitivanja polimernih nanokompozita s ciljem modifikacije navedenih svojstava.
Znanstveno-istraživačka djelatnost Zavoda za organsku kemiju u razdoblju 2009. – 2019.
Authors: Gazivoda Kraljević Tatjana , Vuk Dragana , Škorić Irena , Raić-Malić Silvana , Hranjec Marijana
Published: October 2019

Od osnutka Zavoda za organsku kemiju Fakulteta kemijskog inženjerstva i tehnologije Sveučilišta u Zagrebu, koji je 1922. god. osnovao prof. dr. Ivan Marek, te kasnije preko djelovanja nobelovca Vladimira Preloga i brojnih uspješnih generacija organskih kemičara, vidljiv je utjecaj ne samo na znanstvenu djelatnost Zavoda nego i na cjelokupnu hrvatsku kemijsku zajednicu, osobito u području organske sintetske i medicinske kemije. Preparativnu organsku kemiju profesor Prelog držao je nužnom odrednicom studija, koja je zahvaljujući njegovu djelovanju u Zavodu (1935. – 1941.) ostala glavna okosnica znanstveno-istraživačkog rada. Od samog osnivanja u laboratorijima Zavoda odvijaju se istraživanja iz područja sintetske organske i medicinske kemije i fotokemije, stječu se znanstveni stupnjevi i obrazuju brojni organski kemičari, među kojima su danas mnogi priznati znanstvenici u Hrvatskoj i svijetu.
Impact of left ventricular outflow tract flow acceleration on aortic valve area calculation in patients with aortic stenosis
Authors: Ahmed Andaleeb A. , Matyal Robina , Mahmood Feroze , Feng Ruby , Berry Graham B. , Gilleland Scott , Khabbaz Kamal R.
Published: October 2019

Objective: Due to its circular shape, the area of the proximal left ventricular tract (PLVOT) adjacent to aortic valve can be derived from a single linear diameter. This is also the location of flow acceleration (FA) during systole, and pulse wave Doppler (PWD) sample volume in the PLVOT can lead to overestimation of velocity (V1) and the aortic valve area (AVA). Therefore, it is recommended to derive V1 from a region of laminar flow in the elliptical shaped distal LVOT (away from the annulus). Besides being inconsistent with the assumptions of continuity equation (CE), spatial difference in the location of flow and area measurement can result in inaccurate AVA calculation. We evaluated the impact of FA in the PLVOT on the accuracy of AVA by continuity equation (CE) in patients with aortic stenosis (AS).

Methods: CE-based AVA calculations were performed in patients with AS once with PWD-derived velocity time integral (VTI) in the distal LVOT (VTILVOT) and then in the PLVOT to obtain a FA velocity profile (FA-VTILVOT) for each patient. A paired sample t-test (P < 0.05) was conducted to compare the impact of FA-VTILVOT and VTILVOT on the calculation of AVA.

Result: There were 46 patients in the study. There was a 30.3% increase in the peak FA-VTILVOT as compared to the peak VTILVOT and AVA obtained by FA-VTILVOT was 29.1% higher than obtained by VTILVOT. p]Conclusion: Accuracy of AVA can be significantly impacted by FA in the PLVOT. LVOT area should be measured with 3D imaging in the distal LVOT.
Antagonistic effects of RAC1 and tumor-related RAC1b on NIS expression in thyroid
Authors: Faria Márcia , Félix Daniela , Domingues Rita , Bugalho Maria João , Matos Paulo , Silva Ana Luísa
Published: October 2019

Thyroid cancer (TC) is the most common endocrine malignancy. The sodium–iodide symporter (NIS), responsible for active transport of iodide into thyroid cells, allows the use of radioactive iodine (RAI) as the systemic treatment of choice for TC metastatic disease. Still, patients with advanced forms of TC often lose the ability to respond to RAI therapy, which results in worse survival rates. We have shown that the overexpression of RAC1b, a tumor-related RAC1 splice variant, is associated with less favorable clinical outcomes in differentiated TCs derived from the follicular epithelial (DTCs). RAC1b overexpression is also significantly associated with the presence of MAPK-activating BRAFV600E mutation, which has been previously implicated in the loss of NIS expression. Here, we show that increased RAC1b levels are associated with NIS downregulation in DTCs and demonstrate that ectopic overexpression of RAC1b in non-transformed thyroid cells is sufficient to decrease TSH-induced NIS expression, antagonizing the positive effect of the canonically spliced RAC1 GTPase. Moreover, we clearly document for the first time in thyroid cells that both NIS expression and iodide uptake are hampered by RAC1 inhibition, highlighting the role of RAC1 in promoting TSH-induced NIS expression. Our findings support a role for RAC1 and RAC1b signaling in the regulation of NIS expression in thyroid cells and suggest that RAC1b in cooperation with other cancer-associated signaling cues may be implicated in the response of DTCs to RAI therapy.
PEMBANGUNAN DAN FEMINISASI TANAH DI INDONESIA (KAJIAN EKOFEMINISME GLOBAL)
Authors: Sulistyati Mardian
Published: October 2019

Abstract. Until now, the development process in most Third World countries including Indonesia still places women as second-class citizens; while leaving a latent environmental crisis problem. This paper examines the influence of development practices through the face of mining corporations, and examines the experiences of the struggles of the people who are in the circle of power relations. The global ecofeminism approach of Vandana Shiva and Maria Mies is used as a linguistic nomenclature that helps explain each of the key words in concepts that have previously been tendered by the patriarchal power system. In the end, the value of ecofeminism as the ethics of life becomes a solutive choice to restore traditional and relational awareness that transcends the binary barriers of the human genitals, and transcends the boundaries of human egoism towards non-humans.Abstrak. Hingga kini, proses pembangunan di sebagian besar negara Dunia Ketiga termasuk Indonesia masih menempatkan perempuan sebagai warga kelas dua; sekaligus menyisakan problem krisis lingkungan yang laten. Tulisan ini mengkaji pengaruh praktik pembangunanisme melalui wajah korporasi tambang, serta mengkaji pengalaman perjuangan masyarakat yang berada di dalam lingkar relasi kuasa tersebut. Pendekatan ekofeminisme global Vandana Shiva dan Maria Mies digunakan sebagai nomenklatur linguistik yang membantu memaparkan setiap kata kunci dalam konsep- konsep yang sebelumnya telah tergenderkan oleh sistem kuasa patriarki. Pada akhirnya, nilai ekofeminisme sebagai etika kehidupan menjadi pilihan solutif untuk mengembalikan kesadaran tradisional dan relasional yang melampaui sekat-sekat biner kelamin manusia, serta melampaui sekat egoisme manusia terhadap non-manusia.
NARASI PERJUANGAN KATINI KENDENG DALAM PERSPEKTIF EKOLOGI LIBERATIF AL-QURAN
Authors: Muhammad Wildan Imaduddin
Published: October 2019

Abstract. The Women Farmer from Mount Kendeng a.k.a Kartini Kendeng are persistence to refuse the operation of cement factories and its mining in their land. They are representative of consevasion movement to not defferred to corporation and goverment for their own land and water. This article illustrates narratively the fighting of Kartini Kendeng trhough the perspective of ecology and liberation in the Quran. It is the convergence of thought from three women scholars are Nur Arfiyah Febriani, Amina Wadud and Asma Barlas. Those women agree that Quran is book of liberation from any oppression and despotism. By viewing the Quran as book of liberation, this research consider that Kartini Kendeng are appropriate with Quranic values. In other word, the religious preaching has been motivates the persistent of Kartini Kendeng.Abstrak. Para petani perempuan dari lereng Pegunungan Kendeng atau dikenal dengan Kartini Kendeng sangat gigih menolak operasi Pabrik Semen dan penambangan. Mereka adalah representasi pejuang ekologi yang enggan mengalah dari korporasi yang didukung Negara demi kelestarian tanah dan air. Tulisan ini memotret narasi perjuangan kartini kendeng dengat perspektif ekologi dan liberasi dalam Al-Quran. Perspektif ekologi dan liberasi Al-Quran merupakan konvergensi dari pemikiran tiga tokoh: Nur Arfiyah Febriyani, Amina Wadud dan Asma Barlas. Ketiga tokoh ini sepakat bahwa al-Quran adalah kitab pembebasan dari segala bentuk penindasan dan kesewenangan. Dengan memosisikan al-Quran sebagai kitab liberasi, penelitian ini melihat bahwa perjuangan Kartini Kendeng telah sesuai dengan nilai-nilai dalam al-Quran. Salah satu kesimpulan penelitian ini adalah bahwa ajaran agama turut menjadi motivasi perjuangan para Kartini Kendeng.
PENCEGAHAN, PERLINDUNGAN DAN PENANGANAN KEKERASAN TERHADAP ANAK DAN REMAJA
Authors: Kustanty Ulfah Farida
Published: October 2019

Abstract. This article is motivated by violence that occurs in children and adolescents who can negatively influence if not sought and anticipated factors that influence it. In general, this article aims to identify and analyze the prevention, protection and treatment of violence against children and adolescents. Violence is an act committed by a person or a number of people who are strongly positioned to a person or a number of people who are weak (weak/weak), whose means of strength, both physically and non-physically deliberately committed to cause suffering to the object of violence. What makes children vulnerable to violence are: unharmed families, parents who abuse addictive substances or suffer mental disorders, neglect or neglect, inappropriate or aggressive behavior in the classroom, fail or be less accountable to schools, limited social skills and join friends who use alcohol or drugs or participate in other risky behaviors. Actions that can be done include: Preventive action, educative action, curative action and rehabilitative action. In this issue the role of parents, community, and government is very important to make children and adolescents physically and mentally healthy and able to live in society appropriately.Abstrak. Artikel ini dilatarbelakangi oleh kekerasan yang terjadi pada anak dan remaja yang dapat berpengaruh negatif jika tidak dicari dan diantisipasi faktor-faktor yang mempengaruhinya. Secara umum artikel ini bertujuan untuk mengetahui dan menganalisis pencegahan, perlindungan dan penanganan kekerasan terhadap anak dan remaja. Kekerasan adalah suatu tindakan yang dilakukan oleh seseorang atau sejumlah orang yang berposisi kuat (merasa kuat) kepada seseorang atau sejumlah orang yang berposisi lemah (dipandang lemah/ dilemahkan), yang dengan sarana kekuatannya, baik secara fisik maupun non-fisik dengan sengaja dilakukan untuk menimbulkan penderitaan kepada obyek kekerasan. Yang menyebabkan anak rentan menjadi korban kekerasan adalah : keluarga yang tidak harmonis, orang tua yang menyalahgunakan zat adiktif atau menderita gangguan mental, pengabaian atau penelantaran, perilaku tak pantas atau agresif di kelas, gagal atau kurang bertanggung jawab pada sekolah, kecakapan sosial yang terbatas dan ikut teman yang menggunakan alkohol atau narkoba atau ikut serta dalam perilaku yang beresiko lainnya. Tindakan yang dapat dilakukan diantaranya adalah : tindakan Preventif, tindakan edukatif, tindakan kuratif dan tindakan rehabilitatif. Dalam permasalahan ini peran orang tua, masyarakat, dan Pemerintah sangatlah penting untuk menjadikan anak dan remaja sehat fisik dan mental dan dapat hidup di masyarakat dengan sewajarnya.
Nursing approach to the use of buttonhole and rope ladder cannulation of arteriovenous fistula based on a survey in Nigeria
Authors: Jared M , Rajki V
Published: October 2019

Purpose

The main purpose of this study is to examine the nursing aspect of two types of cannulation techniques and to investigate the outcomes of using cannulations on an arteriovenous fistula, as well as analysing their impact on outcome.

Materials and methods

Data were collected using a self-developed questionnaire. Data were obtained from haemodialysis (HD) patients in Rivon Dialysis Centre in the city of Rivers State named Port Harcourt with over 60 HD patients and with over 15 HD nurses. Only 50 patients met the inclusive criteria after answering the questionnaire, 25 for rope ladder (RL) and 25 for buttonhole (BH) and 10 nurses chosen answered the questionnaire.

Results

This study revealed that patients who are using the BH cannulation technique reported a better outcome than the RL group patients. Patients reported lower occurrence of complication, for instance, out of 25 patients, 8 of them using the BH and 15 of them using the RL reported to have infection.

Conclusion

Based on the results, it is possible to conclude that the patients who are cannulated with the RL cannulation technique have a higher risk of experiencing complications than the patients using the BH site cannulation technique.
2-es típusú diabetesesek és nem cukorbetegek területen szerzett, belgyógyászati osztályos felvételt igénylő bakteriális infekcióinak klinikai összehasonlítása
Authors: Barkai László József , Sipter Emese , Csuka Dorottya , Baló Tímea , Nébenführer Zsuzsa , Máthé András , Karádi István , Pánczél Pál , Prohászka Zoltán , Hosszúfalusi Nóra
Published: October 2019

Abstract:

Introduction: Previous data showed bacterial infections among diabetic patients to be more serious and frequent, with higher mortality rates in comparison with non-diabetics. Recent investigations, however, are contradictory. Aim: The goal of our prospective, observational study was to compare patients hospitalized on a general medical ward due to community-acquired bacterial infections with type 2 diabetes mellitus (T2DM) to those of non-diabetics (K) by 1) infection localization, 2) spectrum of pathogens, 3) three-month mortality rates. Method: Patients were consecutively involved (T2DM: n = 205, K: n = 202). We characterized the infections, clinical parameters, mortalities of the two groups, and matched them to international data. Results: No difference regarding clinical details of the groups were found except for glycemic parameters and BMI. In the T2DM group the skin- and soft tissue- (37.1%), in the K patients respiratory infections (37.1%) were the most common, followed by urinary ones (31.2% and 31.7%, respectively). Skin- and soft tissue infection incidence among T2DM subjects were higher compared to international results (37.1% vs. 16%). Co-presence of Gram positive and Gram negative bacteria in the skin- and soft tissue infections (23/76 vs. 5/46, p = 0.0149), and polymicrobial origin in the urinary tract infections (34.0% vs. 15.1%, p = 0.0335) were found to be more frequent in T2DM than in K. No difference regarding mortality rates were detected. In T2DM the skin- and soft tissue while in the K group the respiratory infections had the most death counts. Conclusions: We found higher rates of skin- and soft tissue infections among T2DM patients hospitalized on a general medical ward compared to international data. In total we did not find difference regarding three-month mortality between the groups. Our results highlight the importance of primary prevention and shows its inadequacy concerning skin and soft tissue infections among type 2 diabetics in Hungary. Orv Hetil. 2019; 160(41): 1623–1632.
A simplified numerical method to simulate the thawing of frozen soil
Authors: Loli Marianna , Tsatsis Angelos , Kourkoulis Rallis , Anastasopoulos Ioannis
Published: October 2019

Thawing weakens the frozen soil supporting buildings and lifelines from Siberia to Alaska, resulting in settlements up to hundreds of millimetres during a single season. This paper presents a simplified sequentially coupled numerical approach that can be implemented in a general purpose, commercially available finite-element analysis model. It is intended to provide a reasonably accurate computational tool for the analysis of structures on degrading permafrost, allowing modelling of complex three-dimensional geometries and boundary and loading conditions. The method permits simulation of the temperature-dependent thermal and mechanical properties of soils in an approximate manner. It accommodates large-strain consolidation theory, also allowing use of plasticity constitutive relationships. A thorough validation study was carried out involving comparison with monotonic and cyclic thaw consolidation element tests, analytical solutions and a well-documented case study of an unstable roadway embankment. The latter was complemented by an investigation of thaw-settlement remediation solutions using thermosyphons, with emphasis on the three-dimensional response and their transverse spacing.
Experimental and analytical study on electro-osmosis in low-permeability soil considering the pore size effect
Authors: Zhou Haijun , Fang Yingguang , Chen Minghua , Gu Renguo , Li Wei
Published: October 2019

Existing electro-osmotic calculation models are mostly based on the assumption of a porous medium with uniform pores, whereas natural soil has pores of different sizes. This is especially significant in the case of low-permeability soil, whose pore size can vary over five or six orders of magnitude, from the nanometre to the millimetre scale. Experimental results have revealed significant differences in the electro-osmotic flow characteristics of soils with various pore sizes, indicating a strong dependence on pore size distribution (PSD). This dependence is termed the pore size effect (PSE) on electro-osmosis. In this paper, a series of one-dimensional electro-osmosis experiments on three types of low-permeability clay soil are conducted to quantify the PSE on electro-osmosis. Based on the experimental results and an analysis of electro-osmotic characteristics, a modified analytical approach considering the actual soil PSD and its effect on electro-osmosis is proposed and thereby two modified analytical models are established. Using the experimental results, the modified models are compared with the existing Helmholtz–Smoluchowski model and other models that assume uniform pores. The results show that the PSE increases with increasing thickness of the electric double layer and that the modified models can be used to reasonably calculate the electro-osmotic permeability of low-permeability soil.
Native and Non-Native EFL Teachers Dichotomy: Terminological, Competitiveness and Employment Discrimination
Authors: Dervić Mersad , Bećirović Senad
Published: October 2019

The application of ‘native’ and ‘non-native’ labels to EFL professionals has been influenced by the argument over their discriminatory nature. L1 proponents claim that natives are innate with linguistic competence while non-natives are referred to as second-best. A review of studies investigating the coherence of these terms supported the validity of this phenomenon. However, competing theories emphasise the importance and impact of discriminatory terminology not addressed by natives This paper looks at this debate in some detail and aims to balance the need for accurate descriptive labelling against the damaging effects of pejorative categories. It also discusses teaching and linguistic competence in light of both “native” and “non-native” categories. The discourse focuses on the advantages and disadvantages attributed to the native versus non-native EFL teacher and employment discrimination issues faced by non-native EFL teachers in institutions, job advertisements, and in the administration of institutions themselves today. It was concluded that a more refined approach to describing different types of EFL professionals is required, which does not negatively disadvantage either L1 or L2 teachers of English.
test v1
Authors: Brown Dillan
Published: October 2019

test
MojoSort™ Human CD4 T Cell Selection Protocol v2
Authors: Li Sam
Published: October 2019

Product description and procedure summary:This kit is designed for the sequential positive selection of CD4+ T cells from human peripheral blood mononuclear cells (PBMCs). Human monocytes express both CD14 and CD4. When using only CD4 Nanobeads for positive selection of human CD4 T cells, monocytes could be isolated along with the T cells. If this monocyte fraction does not impact your application, there is no need to address it. However, not including this population may be required. Thus, the first step in this kit is the depletion of CD14+ cells using a combination of biotin anti-human CD14 and Streptavidin Nanobeads. The second step is the positive selection of the CD4 T cells using directly conjugated CD4 Nanobeads. After collection of the targeted cells, downstream applications include functional assays, gene expression, phenotypic characterization, etc. Note:This procedure is optimized for the isolation of 107 to 2 x 108 cells per tube. If working with fewer than 107 cells, keep volumes as indicated for 107 cells. For best results, optimize the conditions to your specific cell number and tissue. Prepare fresh MojoSort™ Buffer solution by diluting the 5X concentrate with sterile distilled water. Scale up volumes if using 14mL tubes and Magnet, and place the tube in the magnet for 10 minutes.
Transformation of the Krasnoyarsk Urban Space in the 90s of the 20th Century
Authors: Lusan Vladimir S. , Pimenova Natalia N. , Khrebtov Mikhail Ya. , Khudonogova Anastasia E , Sertakova Ekaterina A. , Shimanskaya Kseniya I.
Published: October 2019

The article attempts to uncover the transformation of the urban environment of Krasnoyarsk, starting from the moment of its foundation until the end of the 20th century, as well as the influence of certain spheres of life (culture, industry, transport infrastructure, administrative and territorial position, etc.) and the environment on its formation. The article notes that the analysis of domestic and foreign studies of urban space confirms the validity of an appeal to an interdisciplinary type of research. The object of the research is the city of Krasnoyarsk as an actively developing metropolis with a rich history and its own administrative and cultural characteristics. The subject of research is the urban space of Krasnoyarsk. Observation and analytical and descriptive methods, which include the analysis of individual elements of the development of urban space in the specified period, followed by a generalization of the data, as well as comparative historical and dialectical methods, are used to solve the problems of the study. In addition, the main research methods include the analysis of architectural objects constructed in various years. In conclusion, the general conclusions and trends that characterize the specifics of the urban space of Krasnoyarsk, formed by the end of the 20th century and largely predetermined its development in the third millennium, are indicated
Krasnoyarsk Urban Environment: Main Characteristics
Authors: Zamaraeva Yulia S. , Kistova Anastasia V. , Kolesnik Maria A. , Koptseva Natalia P. , Reznikova Ksenia V. , Seredkina Natalia N. , Sitnikova Aleksandra A.
Published: October 2019

The article discusses the main features of the urban architecture of Krasnoyarsk, the specifics of public transport and the availability of urban space for residents, the problems of public safety in the city; features of parks and public recreation areas; the peculiarity of urban management and the involvement of citizens in the processes of city management. The study is based on modern approaches to the consideration of the urban environment as a result of the interaction of residents and city government. The article is based on a wide range of sources: modern studies of the urban environment in Russia and abroad, official sites of the administration and city services, statistics, modern studies of the urban environment of Krasnoyarsk conducted by scientists of the Siberian Federal University. The results of the study reveal the transitional state of the urban environment of Krasnoyarsk, its rich potential and indicate the main problems and prospects for further development
Using Behavior Skills Training and Other Environmental Manipulations to Teach Safety Skills to Adolescents with ASD
Authors: Rizzi D. , Dibari A.
Published: October 2019

Choosing the correct target behavior to teach is fundamental for parents, teachers, therapists and other professionals working with people with autism and other intellectual disabilities. While early intensive behavioral intervention (EIBI) for young children diagnosed with autism can produce large gains in social, cognitive, and language development, choosing the appropriate curriculum for adolescents and adults warrants some further reflections. Starting from puberty and adolescence, the focus of teaching should move from what the student is missing with respect to typically development peers to what the student needs to become an effective adult, with the final outcome of “making a life”. Applied Behavior Analysis is effective in teaching functional skills, adaptive skills, daily living skills, safety skills, sexuality, physical exercise, self-advocacy and other often overlooked skills that can contribute to the improvement of the quality of life of people with or without disabilities. Research suggests that working on functional skills provided through a meaningful curriculum leads to a more independent life. During this presentation the contribution ABA can offer in developing a meaningful curriculum for adolescents will be reviewed. Particular focus will be placed on using Behavior Skills Training (BST) and other environmental manipulations to teach safety skills to adolescents and young adults with autism spectrum disorders. Examples of safety skills include abduction prevention, seeking help if lost, inappropriate physical contact and information disclosure. The use of technology in teaching safety skills to students with a poor repertoire of verbal behavior will be discussed.
Tutor Support Practices with Children with Severe Forms of Autism in Elementary School
Authors: Gordeeva S.B.
Published: October 2019

Autism spectrum disorders belong to the category of disorders that impede the process of educating children, which is often ineffective without tutorial support. Examples of tutor practice, support techniques of children with intellectual disabilities and detailed comments on cases are presented. Tutor support realized in the school department of the Federal Resource Center for the Organization of Comprehensive Support to Children with ASD. Education was provided in adopted general education program of primary general education for students with health limitations (Program 8.4). The differences in the functions of the tutor and teacher in the classroom, the importance of observing ethical rules in communicating with the children, colleagues and parents are emphasized.