bluuebunny/crossref_metadata_2025 huggingface dataset:
Analisis Semiotika Peirce pada Kajian “Healing dengan Al-Qur’an”
Authors: Arnita Sri
Published: January 2023

Beberapa bulan terakhir ini, ada satu tren penyembuhan yang sedang ramai diperbincangkan di Indonesia yaitu healing. Healing berasal dari bahasa Inggris yang berarti penyembuhan atau pemulihan. Namun, permasalahannya adalah bahwa banyak masyarakat khususnya anak muda yang telah menyalahartikan healing. Kebanyakan orang memaknai healing dengan liburan dan menghabiskan uang saja. Padahal, healing sesungguhnya adalah segala jenis penyembuhan yang tidak mengandalkan obat-obatan. Penelitian ini menggunakan metode kualitatif dengan pendekatan studi kasus untuk memahami makna Healing dengan Al-Qur’an pada channel YouTube Hanan Attaki. Adapun analisis pada penelitian ini menggunakan teori semiotika yang dikembangkan oleh Peirce. Berdasarkan hasil penelitian bahwa salah satu healing terbaik yang menenangkan hati dan jiwa yaitu membaca Al-Qur’an karena pada hakikatnya Al-Qur’an memang diturunkan untuk menjadi obat bagi orang-orang yang beriman. Healing dengan Al-Qur’an tentunya sangat sederhana karena tidak perlu mengeluarkan biaya. Selain itu, healing dengan cara ini justru akan mendatangkan pahala. Cara healing dengan Al-Qur’an yaitu dengan mencari ayat-ayat tematik yang sesuai dengan permasalahan yang sedang dialami, membaca ayat tersebut secara berulang-ulang, kemudian memaknai apa yang dibaca dengan pemaknaan yang dalam (tadabbur). Membaca berulang-ulang suatu ayat Al-Qur’an menjadikan ayat tersebut memiliki kekuatan yang dahsyat.
KONTEKS LIVING QURAN ala UMAR BIN KHATAB
Authors: Fina Indaturrohmah FINA INDATURROHMAH
Published: January 2023

Umar as a caliph as well as a friend of the Apostle has a special position in the history trajectory. His assertive and rigorous personal attitudes lead him became the Khulafa ar Rashidun who is highly respected by Muslims. However, his personal attitudes sparked uproar and even fierce opposition among Muslims at that time, especially when he served as caliph who - it was assumed - often ignored and disobeyed the text of the Quran and the Sunnah of the Prophet Muhammad SAW. This paper used a qualitative approach and specified on literature review method, by collecting data and information from various relevant literature including both text books and internet sources. The results of this study confirmed that Umar's understanding of the text is a product of contemporary Muslim thought. In addition, Umar bin Khattab's hermeneutics can be learned from his understanding of text exposition, implementation based on the text understanding, and his progressive ijtihad in producing benefit-based law.
PENGARUH ZAT BERBAHAYA DALAM MAKANAN HARAM PERSPEKTIF AL-QUR’AN MENURUT WAHBAH ZUHAILI
Authors: Ihwan Agustono  , Destine Najiha Obey
Published: January 2023

Some imported and exported food products are doubtful because they do not meet the halal certification requirements. Unfortunately, some Indonesia still consume food with no-halal certificate due to a lack of information that packaged food products must receive halal certification. Halal assessment through halal certification is very crucial as a halal guarantee from authoritative parties. In addition, the halal status of the food consumed affects the human soul. This research employs a descriptive analysis method using Tafsir Munir as a primary source. The results show, according to Wahbah Zuhaili, that there is an influence of haram food in human life from various aspects. Food ingredients will affect aspects of human health, morals, and religion. When food intake is good, all aspects of life are good, and vice versa. Unless the group of people whom Allah has given an exception, those who are in an exigent situation where there is no other choice but to consume haram food.
MARITAL RAPE DALAM AL-QUR’AN:
Authors: Rofiatul Windariana
Published: January 2023

Marital rape is understood as an act of rape within a marriage. In Islamic law, the issue of coercion in sexual relations receives less attention due to the domination of patriarchy and a lack of understanding of religion, especially the existence of interpretations that are still gender-biased. The verse that is often used as legitimacy for ownership of women's bodies is Qs. Al-Baqarah (2): 222-223. Although this action has been given legal punishment in the legal system, analysis of this verse's interpretation is insufficient to become a starting point in producing the antithesis of an understanding that tolerates it. Through the interpretation function theory of Jorge J.E Gracia as a hermeneutical foundation, this study seeks to examine Hamka's relevant interpretation in Tafsir Al-Azhar to obtain alternative understandings that are relevant to today's context. Interpretation of Al-Azhar is considered relevant as a representation of interpretation which is closely intertwined with Indonesian sosial culture so it is possible to examine this phenomenon through different contexts of revelation and interpretation as well as the implications of the meanings of both related to the phenomenon of marital rape. Through this method, the conception offered by Hamka begins to focus on sosial aspects and shows significant differences between the context of revelation and the context of interpretation regarding the roles of husband and wife, as well as the relationship between the two.
Content Analysis of the Environmental Dimension of Sustainability Reports of Companies in the BIST Sustainability Index
Authors: Horasan Emre , Akarsu Osman Nuri
Published: January 2023

Bireyler ve kuruluşlar kendi ihtiyaç ve istekleri uğruna dünyanın yer altı ve yer üstü kaynaklarını tüketerek hem gelecek nesillerin hem de dünyanın devamlılığını ve sürdürülebilirliğini yok edebilmektedirler. Bu nedenle de ister devlet ister şirket olsun bütün ekonomik birimlerin faaliyetlerinin çevresel ve sosyal etkilerinin sınırlandırılması fikri ve uygulamaları giderek önem kazanmaktadır. Borsa İstanbul’daki (BIST) şirketler arasından sürdürülebilirlik performansı yüksek olanlar Sürdürülebilirlik Endeksi’nde yer almakta ve sürdürülebilirliğe ilişkin faaliyetlerini her yıl gönüllü bir şekilde kamuya sürdürülebilirlik raporlarıyla açıklamaktadırlar. Bu çalışmada 2018 – 2019 ve 2020 – 2021 dönemlerinde BIST Sürdürülebilirlik Endeksi’nde yer alan 38 şirketin sürdürülebilirlik raporları aracılığıyla, çevresel sürdürülebilirliğe ilişkin uygulamaları ve açıklamaları incelenmiş, ifadelerin kullanımları şirketler ve sektörler açısından karşılaştırılmıştır. Çalışma kapsamında belirlenen 41 çevresel bildirim ifadesinin kullanımına ilişkin yapılan içerik analizinin sonuçlarına göre; her iki dönemde de çevre ve iklim en fazla kullanılan ifadeler olduğu gözlenmiştir. 2018 – 2019 döneminde toprak kirliliği, görüntü kirliliği, gürültü kirliliği ve 2020 – 2021 döneminde atık kontrolü, toprak kirliliği en az kullanılan ifadeler olurken çevre denetimine ve yeşil finansa hiç yer verilmemiştir. Ayrıca her iki dönemde de sektörel bazda holding ve yatırım şirketleri ile bankalar en fazla, bilişim ve savunma sektörleri en az ifadeye yer vermiştir. Karşılaştırma sonucunda genel olarak ifade kullanımlarının giderek arttığı, ifadelerin sıklığının ve öneminin değiştiği, bazılarının ise sonraki dönemde hiç kullanılmadığı görülmüştür.
The Collapse of the “Soviet Empire”: Ukrainian Scenario
Authors: Shishkov V.
Published: January 2023

The article explores the problems associated with the collapse of multinational states. On the example of political processes in the Ukrainian SSR, the reasons that led to the collapse of the Soviet Union are considered. The scientific literature presents an interpretation of these processes from the standpoint of the “imperial paradigm” as a natural result of the development of the USSR as an imperial and multinational state. The main argumentation of this approach is subjected to critical analysis.
Migration from Central Asia to Russia: Cultural Aspect
Authors: Muratshina K. , Valeeva M.
Published: January 2023

This paper analyses the perception of Russian culture by labour and student migrants from Central Asia (Kazakhstan, Kyrgyzstan, Tajikistan, Uzbekistan and Turkmenistan). The authors have conducted field research in order to define the migrants’ knowledge, participation in cultural exchanges, and the sources they use to extract information regarding the culture of the recipient country.
Moldova: Irreversible Turn to the West?
Authors: Solovyev E.
Published: January 2023

According to the results of the presidential 2020 and parliamentary 2021 elections, the period of divided rule in Moldova was completed and control over the parliament, the government and the president was in the hands of supporters of the pro-Western orientation party PAS. They received full power and the opportunity, in the context of turbulence in international relations, to ensure the turn of economic ties, trade flows and public opinion to the West. Nevertheless, as the results of sociological researches show, so far the majority of Moldovan citizens support the sovereignty and neutral status of the country, readiness to cooperate with both Western countries and Russia. Hence the desire of the authorities to put pressure on the opposition and seize full control over the media. The answer to the question of whether the turn to the West, undertaken under the leadership of the President of Moldova M.Sandu, irreversible in character depends on a number of factors, the key among which are the success of the socio-economic development model and the presence of a request in society to join European structures and active interaction with NATO.
On the Central Asia’s Strategic Importance for the US
Authors: Davydov A.
Published: January 2023

The article presents an assessment of strategic importance of the Central Asian states for the United States. The analysis is based on the positioning of these states in key strategic documents of the U.S. since early 1990s, and also on trade, investments, aid, and military statistics. Author comes to the conclusion that Central Asian states do not present vital strategical interest for the United States, and the U.S. relations with them are mainly determined by Washington’s strategies in the nearby regions. In this regard these relations have good potential for development in the midterm, but do not present significant importance in the long-term.
European Union and Post-Soviet Countries: New Trends in Development Assistance
Authors: Kvashnin Y.
Published: January 2023

The article analyzes the policy in the field of international development assistance implemented by the EU in the post-Soviet space. It is shown that in the second half of the 2010s – early 2020s the largest European donor countries perceived this region as peripheral. The main part of the funds was allocated by the supranational authorities of the EU. Geographically, most official development assistance (ODA) was provided to Eastern European countries and the South Caucasus, while development assistance to Central Asia was financed on a residual basis. After the crisis in Ukraine escalated in 2022, the EU’s collective ODA increased sharply, and the country itself became the main recipient of European assistance. However, the bulk of aid is expenditure on refugees in donor countries, which is statistically recorded as ODA. Financing of projects on the territory of Ukraine itself is not so significant. In the context of the degradation of relations between Russia and the West, the EU countries are interested not so much in the reconstruction of the Ukrainian economy, but in using the anti-Russian potential of Ukraine. In this regard, not economic, but military assistance is of paramount importance.
Belarus: Relations with Russia in the Context of New Foreign Policy Realities
Authors: Astakhova S.
Published: January 2023

The activation of NATO on the borders of the Union State strengthens the interaction of Russia and Belarus in the field of military cooperation. By supporting its ally in the western direction, Russia will continue to strive to keep NATO at a remote distance from its borders. The general context of the Russian-Belarusian integration has changed since the beginning of the special military operation. The new economic reality contributes to deepening of integration and expansion of economic cooperation between the two countries in the field of import substitution.
The US Ukrainian Front
Authors: Tsedilina E.
Published: January 2023

Russia’s special military operation in Ukraine, which began in the format of a limited armed conflict, by the efforts of the United States was transformed into a full-scale indirect war of the collective West with the Russian Federation. Formally remaining outside the conflict, the United States is taking an active part in it, providing unprecedented military assistance to Ukraine. The main task of the American leadership is to inflict strategic defeats on Russia without endangering its own territory. On the Ukrainian front, the existential issue of preserving the positions of global dominance for the United States is being resolved, while for Russia this is a matter of preserving its statehood. The stakes for both sides are very high, and their interests are diametrically opposed. Therefore, it is difficult to count on a political and diplomatic settlement of the conflict in the foreseeable future.
FINANCIAL CHALLENGES OF SMEs DURING COVID-19 CRISIS: THE CASE OF SPLIT-DALMATIA COUNTY
Authors: Derado Dražen , Pejković Karla
Published: January 2023

The purpose of the paper is to find out how COVID-19 has affected the sector of SMEs, especially in terms of its access to finance. In doing so we hypothesize that problems arising from both supply side and demand side of the business, have additionally restrained SMEs’ access to finance, thus putting their short-to-medium term position to a threat. Research methodology includes descriptive statistical analysis of the results of a company survey of Croatian enterprises with respect to their current access to finance and expectations for the future. The survey was carried out on a sample of 40 small and medium sized companies in Split-Dalmatia County. The findings show that companies do not perceive many of the business risks as particularly threatening to their businesses. Still, this survey reveals a presence of a series of risks closely related to the current situation caused by COVID-19. These include increasing production costs resulting from rising costs of labor, capital, raw materials and other inputs (e.g. transport and logistics services), followed by increasing tax burden and stagnating productivity. Together with increasing costs, a fall in demand on both domestic and foreign markets, as well as a resulting decrease in sales, announce further problems that call for a strong policy response in the future. The main contribution of the paper is the finding that besides the problem of access to finance, the COVID-19 crisis has revealed other serious obstacles for SMEs which threaten to endanger the market position and competiveness of small business in the long run. By far the most serious problems for Croatian SMEs are that of a structural nature which include increasing costs and decreasing productivity. This research has additionally accentuated some serious obstacles from external environment which threaten to restraint SMEs’ capacity to restructure and keep their competitive edge.
FACTORS OF TOURISTS’ PERCEIVED SAFETY IN THE POST COVID PERIOD: THE CASE OF OPATIJA RIVIERA
Authors: Alkier Romina , Okičić Jasmina , Milojica Vedran
Published: January 2023

Purpose – The pandemic caused by the COVID-19 virus left a significant negative mark on the world economy, and tourism industry. It has also significantly affected the perception and behavior of tourists when it comes to the safety of a tourist destination. To continue to record a positive recovery trend, destinations must undertake scientific and professional research, and based on the results consider and develop new development strategies for the development of tourism in the post-pandemic period. The perception of risk in tourists is changing, which ultimately has an impact on their future behavior when choosing a holiday destination. Opatija Riviera is a destination with a rich and long tourist tradition, which until before the pandemic was perceived as safe, as evidenced by the continuous growth of tourist turnover. The purpose of this paper is to emphasize the importance of monitoring whether and to what extent tourists perceive Opatija Riviera as a safe tourist destination and based on the findings to offer developmental guidelines for the post-pandemic period. Methodology – Data collection was conducted during June and July 2022, using an online survey questionnaire. 152 respondents agreed to participate in research. The basic measurement instrument was based on the Tourists’ Perceived Safety at Destinations (TPSD) scale developed by Xie et al. (2020b), i.e. initial items (25) proposed by these authors. To extract the dimensions of perceived tourist safety, the authors primarily used exploratory factor analysis. Findings – by using the exploratory factor analysis the following factors were identified: perception of safety of human elements (PSH), safety of facilities and equipment (PSFE), safety of natural environments (PSNE), perceived safety of social environments (PSSE) and safety of management elements (PSM). The results for PSH, PSFE, PSNE and PSSE have proven to be satisfactory in terms of how tourists perceive them as safe and reliable, which is not the case with the PSM. The f indings for PSM indicate the need for additional investments aimed towards improvement of protection of tourist´s safety (safety of the construction, safety of information and visibility of warning sign about security in Opatija Riviera). Originality of the research – this research contributes to the theory by presenting relevant literature content in safety perception in tourism. The empirical contribution derives from the fact that no similar research was conducted on Opatija Riviera until now. Its findings set the basis for future empirical research that will be conducted in the post-COVID period in Opatija Riviera, based on which it will be possible to plan further developmental activities aimed towards improving tourist´s safety during their stay.
Desigualdades socioeconómicas y étnico-raciales en la mortalidad de un hijo durante su niñez en México. ¿Qué tanto importa el color de la piel?
Authors: Zazueta Borboa Jesus Daniel
Published: January 2023

En este trabajo se presenta un análisis de las características socioeconómicas y étnico-raciales en México respecto a la probabilidad de mortalidad de un hijo antes de sus cinco años con datos de la encuesta ESRU de Movilidad Social de México de 2017 (del Centro de Estudios Espinosa Yglesias). Se documenta que las mujeres con tono de piel más oscura tienen una probabilidad de perder un hijo antes de que cumpla cinco años de 2,82 (1,39-5,74 IC) veces más alta que las de con de piel más claro. Estos resultados están controlados por diferentes cohortes de nacimiento, características sociodemográficas, territoriales y socioeconómicas. En un escenario contrafactual se estimó que la probabilidad de perder un hijo se explica hasta en un 28,7% por las características étnico-raciales y, por las características socioeconómicas, hasta en un 58,5%. En conclusión, la pérdida de un hijo es un evento demográfico distribuido de manera desigual en la población y está determinado no solo por las características socioeconómicas, sino también por las características étnico-raciales. La idea de mestizaje en México que propone una igualdad étnico-racial en la población demuestra ser errónea y evita salvar vidas.
Mortalidade de mulheres em idade fértil no Brasil de 2006 a 2019: causas e tendências
Authors: Albert Silmara Bruna Zambom , Martinelli Katrini Guidolini , Zandonade Eliana , Theodoro do Santos Neto Edson
Published: January 2023

O objetivo deste estudo é analisar a tendência das principais causas de óbito de mulheres em idade fértil (MIF) no Brasil, por faixa etária, no período de 2006 a 2019. Utilizaram-se dados do Sistema de Informações sobre Mortalidade (SIM) e do Instituto Brasileiro de Geografia e Estatística (IBGE). As principais causas de morte de MIF (10 a 49 anos) foram classificadas por capítulos da Classificação Estatística Internacional de Doenças e Problemas Relacionados à Saúde (CID-10). Posteriormente realizou-se análise de tendência temporal por meio de modelos de regressão polinomial das principais causas de morte de MIF segundo faixa etária. No Brasil, as maiores taxas de mortalidade por causas p/100 mil MIF deveram-se a neoplasias (25,34), doenças do aparelho circulatório (20,15), causas externas (18,69), doenças infecciosas e parasitárias (8,79) e doenças do aparelho respiratório (6,37). Para o período analisado, após padronização, as taxas de mortalidade por doenças do aparelho circulatório, do aparelho respiratório e infecciosas e parasitárias apresentaram tendência decrescente, com uma queda expressiva de 26,6% para as doenças do aparelho circulatório; já as taxas de mortalidade por causas externas e neoplasias registraram tendência crescente de 2006 a 2012 e decrescente de 2013 em diante. As causas externas e as neoplasias foram as principais causas de óbito, especialmente entre as mulheres mais jovens e com tendência crescente. Sendo este um importante problema de saúde pública, faz-se necessário planejar ações que otimizem os recursos e melhorem a qualidade de vida e saúde das mulheres.
Hábito alimentar de adultos brasileiros segundo a condição na força de trabalho
Authors: De Assumpção Daniela , Cocetti Monize , Gomes de Macedo Bacurau Aldiane , Maria Pita Ruiz Ana , Maria Stolses Bergamo Franscisco Priscila
Published: January 2023

O objetivo desse artigo é avaliar o hábito alimentar da população adulta no Brasil segundo a condição na força de trabalho. Realizou-se estudo transversal com dados de 63.782 adultos (18 a 59 anos), participantes da Pesquisa Nacional de Saúde (PNS) 2019. A condição na força de trabalho - ocupado, desocupado ou fora da força - foi relacionada com marcadores de consumo alimentar saudável e não saudável. Estimaram-se razões de chance (odds ratio) ajustadas com regressão logística multinomial. Os resultados apontam que, entre os adultos brasileiros, 71,3% estavam ocupados, 6,7% desocupados e 21,9% encontravam-se fora da força de trabalho. Os ocupados apresentaram maior frequência de consumo de frutas, hortaliças e carne vermelha, e menor de feijão. O consumo de frango, bebidas de frutas, cereais, ovos, margarina e pratos prontos/semiprontos foi mais frequente para os desocupados versus ocupados, enquanto o de peixes e tubérculos foi menos frequente. Os adultos fora da força de trabalho, comparados aos ocupados, mostraram menor frequência de consumo de refrigerantes, embutidos, pães de pacote, oleaginosas, assim como do costume de substituir o almoço por lanches. Observaram-se discrepâncias na alimentação segundo a condição de trabalho, sobretudo no consumo de hortaliças, frutas, carnes e feijão, denotando a necessidade de iniciativas de promoção da alimentação adequada e saudável voltadas para a saúde do trabalhador.
Koping Diadik sebagai Moderator Kelekatan Menghindar dan Komitmen pada Hubungan Romantis Jarak Jauh
Authors: Rahmadina Susilaningtyas Fira , Nurwianti Fivi
Published: January 2023

Abstract. Building romantic relationship is a developental task for young adults. There are two types of love relationships based on differences in distance, short distance and long distance relationship. Many couples are in long distance relationships, which allows conflict to arise in the relationship. Therefore, commitment is needed for both to be able to maintain a relationship. Attachment is a relational factor that is closely related to the sustainability of the relationship, but on the other hand, individuals with avoidant attachment tend to have low commitment to maintain their relationship. Previous research stated that dyadic coping can increase commitment for individuals with avoidant attachments, so that they are more motivated to maintain their relationship. This study aims to see whether avoidant attachment has a significant relationship with commitment, and whether common dyadic coping and negative dyadic coping moderate the relationship between avoidant attachment and commitment in individuals who are in long-distance relationships. A total 406 participants with an age range of 18-40 years participated in this study. Commitment was measured using the Triangular Theory of Love Scales (Sternberg, 1990); Avoidant attachment was measured using the Experience in Close Relationship Questionnaire-Revised (Fraley, Brennan, Waller, 2000); and Dyadic coping was measured using Dyadic Coping Inventory (Bodenmann, 2008). The results showed that (1) Aoidant attachment was a significant predictor of commitment in long-distance relationships; (2) Common dyadic coping moderates avoidant attachment and commitment in long-distance relationships; (3) Negative dyadic coping does not moderate the relationship between avoidant attachment and commitment. This research is expected to add to the theoretical study of attachment style, commitment, and dyadic coping as well as become a reference material for counselors to deal with clients that having related problems.
Analyzing the effects of digital marketing on brand awareness among internet users
Authors: Karen Karen , Zai Immanuel
Published: January 2023

Information technology advancements have influenced how marketing is carried out in the sector with that, a variety of platforms and methods for raising consumer brand awareness. Digital marketing strategies such as advertising, social media marketing, content marketing, email marketing, and website marketing are well-known and used across a variety of industries in our fast-evolving technology. This article provides a thorough analysis of how various digital marketing strategies related to brand recognition. In light of this, the study design for this work is comparative causal, and the primary data used were those that were gathered from 273 consumers of digital media in the province of Riau Island and evaluated using the SmartPLS program. The theory was put to the test, and the results revealed a significant positive association between internet advertising and brand recognition. The study can be further expanded using data from various age groups, geographic locations, and other digital marketing strategies which wasn’t further studied in this study.
Analisis peran modal intelektual dan BOPO sebagai determinan kinerja perbankan
Authors: Serly Serly , Yaputri Josephine Ardini
Published: January 2023

Studi ini bertujuan untuk menganalisis pengaruh efisiensi modal intelektual dan BOPO terhadap kinerja perusahaan perbankan. Penelitian ini mengangkat profitabilitas sebagai variabel terikat serta melibatkan 41 perusahaan perbankan yang terdaftar di Bursa Efek Indonesia (BEI) yang telah merilis laporan tahunan pada periode 2017-2021. Metode yang digunakan yaitu metode analisis deskriptif kuantitatif dengan pemilihan data secara purposive sampling. Hasil penelitian memaparkan bahwa semua komponen dari efisiensi modal intelektual berpengaruh signifikan kecuali capital employed efficiency  yang merupakan indikasi efisiensi bank dalam menggunakan modal fisik dan keuangannya dalam mendukung bank untuk bertahan di pangsa pasar. Selain itu, BOPO menunjukan pengaruh negatif terhadap kinerja bank karena pengaruhnya berbanding terbalik dengan konsep pengukuran kinerja bank.
Good news on public restriction and stock prices in Indonesia
Authors: Siagian Valentine
Published: January 2023

his paper aims to investigate the impact that the news has on the public's ability to restrict stock prices on the Indonesia Stock Market. There are a total of 18,824 firm-day observations derived from 724 different firms that are listed, and that are observed 25 trading days. In order to validate the data, panel data regression was utilized, and additional regression on each industry was carried out. According to the findings of this paper, the number of specimens that were announced today does, in fact, affect the closed price on the following day. There is a correlation between the total number of cases recovered and stock prices. From an empirical standpoint, even a higher recovered case was unable to provide assurance that the following day's stock prices would remain stable.
Methodological issues in physical exercise and people with spinal cord injury: a multidisciplinary approach is needed
Authors: Martin-Manjarrés Soraya
Published: January 2023

This editorial presents some methodological issues that should be considered when performing physical exercise in people with spinal cord injury (SCI) and raises the need for specific knowledge to adjust the protocols and training programs used in this population.
The effects of taekwondo practice on physical and cognitive variables in children and adolescents: a systematic review
Authors: Gama Diego
Published: January 2023

Taekwondo can develop social responses, beliefs, values, attitudes, and cognitive experiences due to its characteristics and the diversity of frequency, intensity, time, and type of application. This can facilitate the achievement of results related to physical health and cognition in individuals in the formation phases. Thus, this study aimed to analyze the effects of taekwondo practice on physical and cognitive variables in children and adolescents. This systematic review followed the PRISMA recommendations and was registered in PROSPERO (CRD42021293609). The search was performed in the MEDLINE (via PubMed), Scopus, SPORTDiscus, and Web of Science databases. The search terms were related to the theme taekwondo, school, and students with the keywords grouped in a single Boolean phrase: “taekwondo AND school” OR “taekwondo AND students”. Studies that analyzed the effects of taekwondo on health-related variables in children and adolescents of both sexes were included. The risk of bias in experimental and quasi-experimental studies was analyzed using the Cochrane Collaboration tool and the Risk Of Bias In Non-randomized Studies - of Interventions (ROBINS-I) tool, respectively. After using the selection criteria, 8 studies were included. Study interventions consisted of a minimum of 8 weeks and a maximum of 72 weeks. There was a total of 402 participants aged between 6 and 16 years, of which 75% were male. The protocols demonstrated improvement in cognitive performance, strength, flexibility, and balance after taekwondo intervention. We concluded that the practice of taekwondo was able to bring positive responses to physical and cognitive performance in children and adolescents.
Determinants of service quality influencing customer satisfaction in fitness centers: A systematic review
Authors: Ferreira Helena
Published: January 2023

The aim of the present systematic review was to investigate the determinants of fitness center service quality that most influence customer satisfaction. Studies were identified from searches in PubMed, Scopus, Web of Science and EBSCO databases from 2017 through 2022. The search process was carried out by four independent researchers. Titles and abstracts were reviewed to determine whether the studies met the inclusion criteria. The quality of the reporting of the measures was assessed using a tailored list. The electronic search strategy produced 378 studies. A total of 17 articles met the inclusion criteria. Results of the review support the importance of service quality to improve customer satisfaction, leading to customers future intentions with the brand, increasing loyalty and customer retention. Therefore, positive perceptions of service quality influence customer satisfaction, in turn customer loyalty and retention, and are indispensable for the sustainability of these companies. Through the studies included in this systematic review it was possible to identify nine dimensions of service quality as predictors of customer satisfaction: facility quality, instructors and reception staff quality, price, supporting services, service recovery, service assurance, online marketing, and customer relations. This article provides useful and global information on the most current service quality factors. Given the fitness market's competitiveness, understanding the factors that influence service quality allows managers to better choose their strategies for increasing customer satisfaction.
Performance Analysis in Elite Basketball Differentiating Game Outcome And Gender
Authors: Bezerra Marcos
Published: January 2023

Traditionally, basketball research has used game-related statistics in order to discriminate winning and losing teams. Unfortunately, most investigations refer exclusively to the analysis of men's competitions. In this sense, Tokyo 2020 Olympic Games created a unique opportunity to make gender performance comparison feasible, since it provided same period and environmental conditions for both genders. The aim of this study was to identify which game-related statistics best discriminated winning and losing teams in men and women’s team playing Tokyo 2020 Basketball Olympic Tournament. All statistical data for the 26 games of each gender were obtained from the FIBA website. The MANOVA and discriminant analysis models were run to check differences according to gender and game outcome. The main results revealed 2-point field-goals percentage, defensive rebounds, assists, points in the paint, and effective field goal percentage as key variables to succeed in men and women’s games. However, there were gender discrepancies on 2-point field-goals made, points from turnovers, turnover per ball possession rate (relevant only when discriminating men’s winning teams), and fastbreak points, offensive rebounds percentage, and free-throw rate (only for women’s winning teams). Winning and losing discriminant statistics were quite similar for both, men and women’s teams when only considering traditional box-score stats, but not when analyzing advanced stats.
Modelling of biodiesel production from transesterification process of sandbox (Hura crepitans L.) seed oil: performance comparison of artificial neural networks (ANN) and adaptive neuro-fuzzy inference system (ANFIS)
Authors: Ajala Olajide Olukayode , Oyelade Joel Olatunbosun , Oke Emmanuel Olusola , Oniya Oluwole Oluwatoyin
Published: January 2023

Biodiesel has been seen as an alternative to diesel (fossil) fuel as a result of its favourable properties, energy security reasons and environmental benefits. In this research, transesterification of sandbox seed oil with ethanol to form biodiesel has been modelled using artificial neural network (ANN) and adaptive neuro-fuzzy inference system (ANFIS) techniques. Temperature (oC), time (min.), catalyst concentration (w/w) and catalyst type (g) were used as input variables while biodiesel yield was used as output variable for modelling the efficiency of biodiesel production from sandbox seed oil. The results showed that ANN model gave R2 of 0.925, RSME of 2.99255, MAE of 0.62196, SEP of 0.03689 and AD of 0.03194 while ANFIS model gave R2 of 0.961, RSME of 1.97379, MAE of 0.0001, SEP of 0.02433 and AD of 0.000005136. The results prove that ANFIS model is more reliable in predicting biodiesel yield from sandbox seed oil than ANN model.
Effects of Consecutive Rebound Jump Training Dependent on Muscles to which Electromyostimulation is applied
Authors: Ogiso Kazuyuki
Published: January 2023

Background
Consecutive rebound jump (RJ) training performed while applying electromyostimulation (EMS) to the calf muscle increases muscle strength and Achilles tendon stiffness, and enhances jump performances. The present study investigated whether the effects on jumping performance of consecutive RJ training with EMS differed depending on lower limb muscles on which EMS was superimposed.
Methods
Forty-nine men who trained every other day for 4 weeks were divided into five groups: a non-EMS group and EMSCALF, EMSAF, EMSPF, and EMSTHIGH groups in which EMS was applied to the calf, anterior femoris, posterior femoris, and all thigh muscles, respectively. Participants were only instructed to perform RJs at the same spot but were not instructed on jumping action and its kinesthetic sensation.
Results
After training, the jump heights increased in all EMS-applied groups. Kinesthetic sensation and the joint angles in which maximum voluntary isometric contraction torque increased differed depending on the muscles on which EMS was superimposed during RJs. The EMSCALF group experienced a clear “bounce” sensation during jumping and increased ankle plantar flexion torque and Achilles tendon stiffness in the ankle dorsiflexion position. The body was moved backward in the EMSAF group during RJs but forward in the EMSPF group. The EMSTHIGH group felt the easiest to jump during jumping.
Conclusions
The application of EMS to lower limb muscles during RJs enhanced jumping performance, but its mechanism and effects depended on the muscles to which it was applied.
A simulation and experiential learning intervention for labor and delivery providers to address HIV stigma during childbirth in Tanzania: Study protocol for the evaluation of the MAMA intervention
Authors: Watt Melissa H. , Cohen Susanna R. , Minja Linda M. , Barabara Mariam , Mlay Pendo , Stephens Maya J. , Olomi Gaudensia , Mlay Janeth , Marchand Virginie , Mmbaga Blandina T.
Published: January 2023

Background: The experience of HIV stigma during intrapartum care can impact women’s trust in the health care system and undermine their long-term commitment to HIV care engagement. Delivery of respectful maternity care (RMC) to WLHIV can improve quality of life and clinical outcomes. The goal of this study is to conduct an evaluation of MAMA (Mradi wa Afya ya Mama Mzazi, Project to Support the Health of Women Giving Birth), a simulation team-training curriculum for labor and delivery providers that addresses providers’ instrumental and attitudinal stigma toward WLHIV and promotes the delivery of evidence-based RMC for WLHIV.
Methods: The MAMA intervention will be evaluated among healthcare providers across six clinics in the Kilimanjaro Region of Tanzania. To evaluate the impact of MAMA, we will enroll WLHIV who give birth in the facilities before (n=103 WLHIV) and after (n=103 WLHIV) the intervention. We will examine differences in the primary outcome (perceptions of RMC) and secondary outcomes (postpartum HIV care engagement; perceptions of HIV stigma in the facility; internal HIV stigma; clinical outcomes and evidence-based practices) between women enrolled in the two time periods. Will also assess participating providers (n=60) at baseline, immediate post, 1-month post training, and 2-month post training. We will examine longitudinal changes in the primary outcome (practices of RMC) and secondary outcomes (stigma toward WLHIV; self-efficacy in delivery intrapartum care). Quality assurance data will be collected to assess intervention feasibility and acceptability.
Discussion: The implementation findings will be used to finalize the intervention for a train-the-trainer model that is scalable, and the outcomes data will be used to power a multi-site study to detect significant differences in HIV care engagement.
Trial Registration: The trial is registered at clinicaltrials.gov, NCT05271903.
A pilot randomised controlled trial to increase the sustainment of an indoor-outdoor free play program in early childhood education and care services following the introduction of outdoor free play guidelines: a study protocol for the Sustaining Play, Sustaining Health (SPSH) trial
Authors: Imad Noor , Pearson Nicole , Hall Alix , Shoesmith Adam , Nathan Nicole , Giles Luke , Grady Alice , Yoong Serene
Published: January 2023

Background:

Early Childhood Education and Care (ECEC) settings are an important environment to support child physical activity (PA). Increasing the time children have outdoors is associated with increased activity levels. As such, ECEC guidelines recommend that childcare services provide indoor-outdoor free play programs (periods of free play located in both the indoor and outdoor environments) as a way to increase outdoor free play opportunities. In 2021, such recommendations were supported by COVID-19 regulations as a way of reducing the transmission of the virus and increasing social distancing, resulting in an increased uptake of this practice by ECEC services. As the context changes, research suggests that ECEC services could cease the implementation of such practices. The aims of this pilot randomised controlled trial (RCT) therefore, is to examine the feasibility, acceptability, and impact of a sustainment strategy to ensure ongoing implementation (sustainment) of ECEC delivered indoor-outdoor free play programs.

Methods:

Twenty ECEC services located in one state (New South Wales), Australia that have implemented indoor-outdoor free play programs since the release of COVID-19 related health advice will be recruited to participate. Services will be randomly allocated to receive either the sustainment strategy (intervention group) or usual care (control group). The “Sustaining Play, Sustaining Health” program consists of eight strategies, developed to address key barriers and facilitators to sustainment of health promotion programs in ECEC settings informed by the Integrated Sustainability Framework. The 6-month sustainment strategy will be delivered remotely and will target ECEC staff responsible for supporting the implementation of PA programs in the ECEC service. The outcomes are feasibility, acceptability, and impact of the sustainment strategy, which will be measured at 6-months post-baseline. Outcomes will be assessed via internal project records, staff surveys, and a self-reported measure of the amount of indoor-outdoor free play provided. Feasibility and acceptability will be assessed using descriptive statistics and impact will be compared between groups.

Discussion:

This study will provide important data to support the conduct of a fully powered trial within Australian ECEC settings and inform the development of future strategies to sustain population health programs in the setting.

Trial Registration:

Australian New Zealand Clinical Trials Registry (ACTRN12622001089729). Prospectively registered 5th August 2022, ANZCTR - Registration.
RNF8 enhances the sensitivity of PD-L1 inhibitor against melanoma through ubiquitination of galectin-3 in stroma
Authors: Wang Degui , guo yanan , Shen Rong , Yang keren , Wang yutong , Song haoyun , Liu Xiangwen , Cheng xin , Wu rile , Song yanfeng
Published: January 2023

The failure of melanoma immunotherapy can be mediated by immunosuppression in the tumor microenvironment (TME) and insufficient activation effector T cells to against tumor. Here, we show that inhibition of galectin-3 (gal-3) enhances the infiltration of T cells in TME and improves the sensitivity of anti-PD-L1 therapy. We identify that RNF8 downregulated the expression of gal-3 by K48-polyubiquitination and promoted gal-3 degradation via ubiquitin proteasome system. RNF8 deficiency in host but sufficiency in implanted melanoma results immune exclusion and tumor progression due to up-regulation of gal-3. Up-regulation of gal-3 decreased the immune cell infiltration by restricting IL-12 and IFN-γ. Inhibition of gal-3 reverses immunosuppression and induces immune cells infiltration in tumor microenvironment. Moreover, gal-3 inhibitor treatment can increase the sensitivity of PD-L1 inhibitors via increasing immune cells infiltration and enhancing immune response in tumor. This study reveals a previously unrecognized immunoregulation function of RNF8 and provides a promising strategy for therapy of “cold” tumors. Tremendous effects of melanoma treatment can be achieved by facilitating immune cell infiltration combined with anti-PD-L1 treatment.
HDAC inhibitors target IRS4 to enhance anti-androgen receptor (AR) therapy in AR-positive triple negative breast cancer
Authors: He Yang , Ma Yue , Zhu ye , Zhang Yi , Zhao rong , Zhang Di , Xu Danni , zhao peng , Tong sheng
Published: January 2023

Triple negative breast cancer (TNBC) is the most malignant subtype of breast cancer. Androgen receptor (AR)-positive TNBC has been identified as a potential therapeutic target; however, clinical trials have not produced an effective treatment. This study aimed to identify a new treatment regimen to improve the prognosis of AR-positive TNBC. First, we used a combination of an AR inhibitor (enzalutamide, Enz) and selective histone deacetylase inhibitor (chidamide, Chid) to treat AR-positive TNBC cell lines and observed a synergistic effect of the drugs. The combination treatment inhibited cell growth and migration by arresting the cell cycle at the G2/M phase. We used next-generation sequencing to detect changes in gene regulation. The results showed that the PI3K/Akt signalling pathway was significantly inhibited by the combination treatment of Enz and Chid, and gene set enrichment analysis (GSEA) revealed that KRAS signalling was significantly enriched. Analysis of associated genes revealed that insulin receptor substrate 4 (IRS4) plays a critical role in blocking the activation of KRAS signalling. In a mouse xenograft model, combination treatment also inhibited the PI3K/Akt signalling pathway by upregulating the expression of IRS4 and thereby suppressing tumour growth. In conclusion, we found that Enz and Chid combination treatment upregulates IRS4, which results in the blocking of KRAS signalling and suppression of tumour growth. We hypothesize that the expression level of IRS4 can be used as a biomarker for screening patients with AR-positive TNBC using enzalutamide and chidamide combination therapy.
Anti-amphiphysin antibody-associated paraneoplastic brainstem encephalitis with pruritus and dysphagia as the first symptoms: a case report
Authors: Wang Jin , Mi Xiaokun , Ban Feng , Li Ruoyang , Zhao Xuewei , Zhang Yaxi , Zhang Wei , Jia Yaqiong , Zhang Jing , Zhao Jingxia
Published: January 2023

Anti-amphiphysin antibodies are uncommonly detected in paraneoplastic neurologic syndromes (PNS). If this happens, it is likely to present as a stiff-person syndrome (SPS). Here, we report the first case of PNS with pruritus as the first complaint,whose serum examination showed anti-amphiphysin antibodies IG+++, and the lung puncture confirmed small-cell lung cancer (SCLC). During the progression of the disease, the patient developed dysphagia and anxiety. With chemotherapy and paroxetine 20mg/d, his symptoms significantly improved. This case report emphasizes that clinicians should consider diagnoses other than anxiety states or esophageal cancer in a patient with pruritus and dysphagia, such as PNS.
A Prospective Precision Medicine Phase 3 Clinical Trial of Low-dose Ondansetron (a 5-ht3 Antagonist) to Treat Heavy and Very Heavy Drinkers With Alcohol Use Disorder
Authors: Johnson Bankole , Alho Hannu , Addolorato Giovanni , Lesch Otto , Chick Jonathan , Liu Lei , Reich Jack , Schuyler Vinzant , Rodd Zachary
Published: January 2023

This 6-month, double-blind, randomized, Phase-3 clinical trial in Alcohol Use Disorder (AUD; n = 303) tested ondansetron 0.33 mg/twice daily (AD04) vs placebo in reducing the Percentage of Heavy Drinking Days (PHDD) among a genetic subgroup with variations at the serotonin transporter and 5-HT3A/5-HT-3B receptors who consumed < 10 Standard Drinks/Drinking Day (DDD) (heavy drinkers) or ≥ 10 DDD (very heavy drinkers). At Month 6, the least square (LS) mean change in PHDD from baseline was 8.5% greater in the heavy drinkers AD04 group compared with placebo (LS mean (SD): -46.7% (2.7%), 95%CI: -52.1% to -41.2% vs. -38.1% (2.9%), 95%CI: -43.8% to -32.5%; p = 0.03) with lower effect (LS mean difference: 7.0%, p = 0.07) for Months 5 and 6 combined. At Month 6, for the total AD04 group compared with the placebo group, heavy drinkers had a better quality of life (OR = 3.4, 95% CI: 1.03–11.45, p = 0.04), fewer AUD symptoms (Mild: AD04 group 33% vs. placebo group 39%; Severe: AD04 group 10% vs. placebo group 24%) (p = 0.05), and similar adverse event profiles. No treatment-related effects differentiated AD04 and placebo in very heavy drinkers. This study showed AD04’s promise as a precision medicine treatment for heavy drinkers with a specific genetic profile.