bluuebunny/crossref_metadata_2025 huggingface dataset:
Patients With Dragged Optic Disc Vessels and Retinal Folds: Clinical Features, Multimodal Imaging, and Histopathology
Authors: Iyer Prashanth G. , Ashkenazy Noy , Carletti Piero , Hudson Julia L. , Patel Nimesh A. , Sengillo Jesse D. , Kunkler Anne L. , Lazzarini Thomas A. , Khzam Rayan Abou , Tang Vincent , Negron Catherin I. , Dubovy Sander , Flynn Harry W. , Berrocal Audina M.
Published: November 2023

Background and Objective:

To describe the multimodal imaging and histopathological features of patients with dragged optic disc vessels (DODV).

Patients and Methods:

This is a retrospective, observational analysis using multimodal imaging of eyes with DODV in patients with retinal vascular diseases including familial exudative vitreoretinopathy, inflammatory disease, and others. In addition, two additional enucleated eyes with DODV underwent histopathological analysis.

Results:

Of the 13 patients, eight were girls and five were boys. Mean age was 5 years (ranging from 4 months to 10 years old). Of the 15 eyes, 12 (80%) demonstrated temporal dragging and three (20%) had nasal dragging. Retinal vascular abnormalities were present in 11 of the fellow eyes. Multimodal imaging demonstrated features of DODV including direction of traction, outer retinal thickening, increased flow, and other features. Only two (13.3%) eyes required surgical intervention. Mean follow-up was 14 (range 3 to 30 months) months. At last follow-up all eyes remained stable. Last visual acuity ranged from 20/100 to counting fingers. As well, two enucleated globes of adults with retinopathy of prematurity underwent histopathologic evaluation, showing optic nerve fibers that extended from the optic nerve into the DODV.

Conclusions:

DODV is a sign of various late-stage retinal vascular diseases, associated with poor visual function. Multimodal imaging and histopathology can assist in understanding the disease pathology.

[
Ophthalmic Surg Lasers Imaging Retina
2023;54:634–642.]
Optimizing Visual Outcomes in Patients With Neovascular Age-Related Macular Degeneration: the Potential Value of Sustained Anti-VEGF Therapy
Authors: Weng Christina Y. , Singh Rishi P. , Gillies Mark C. , Regillo Carl D.
Published: November 2023

Neovascular age-related macular degeneration (nAMD) leads to irreversible central vision loss if untreated. Frequent administration of anti-vascular endothelial growth factor (anti-VEGF) injections inhibits disease activity with excellent functional and morphological benefits. However, these injections pose a heavy therapeutic burden, and treatment discontinuation is common. Although current anti-VEGF treatment paradigms, such as treat-and-extend, mitigate treatment burden while still leading to acceptable vision outcomes, they fail to sustain initial vision gains for many. Novel longer-acting anti-VEGF therapies may reduce the overall burden on nAMD patients. Gene therapy might offer a paradigm shift by providing continuous expression of anti-VEGF, potentially decreasing treatment requirements and improving long-term vision outcomes.

[
Ophthalmic Surg Lasers Imaging Retina
2023;54:654–659.]
Suppression of absence seizures by using different stimulations in a reduced corticothalamic-basal ganglion-pedunculopontine nucleus model
Authors: Tan Xiaolong , Zhu Rui , Xie Yan , Chai Yuan
Published: November 2023

Coupled neural network models are playing an increasingly important part in the modulation of absence seizures today. However, it is currently unclear how basal ganglia, corticothalamic network and pedunculopontine nucleus can coordinate with each other to develop a whole coupling circuit, theoretically. In addition, it is still difficult to select effective parameters of electrical stimulation on the regulation of absence seizures in clinical trials. Therefore, to develop a coupled model and reduce computation cost, a new model constructed by a simplified basal ganglion, two corticothalamic circuits and a pedunculopontine nucleus was proposed. Further, to seek better inhibition therapy, three electrical stimulations, high frequency stimulation (HFS), 1:0 coordinate reset stimulation (CRS) and 3:2 CRS, were applied to the thalamic reticular nucleus (RE) in the first corticothalamic circuit in the coupled model. The simulation results revealed that increasing the frequency and pulse width of an electrical stimulation within a certain range can also suppress seizures. Under the same parameters of electrical stimulation, the inhibitory effect of HFS on seizures was better than that of 1:0 CRS and 3:2 CRS. The research established a reduced corticothalamic-basal ganglion-pedunculopontine nucleus model, which lays a theoretical foundation for future optimal parameters selection of electrical stimulation. We hope that the findings will provide new insights into the role of theoretical models in absence seizures.
Co-Creating Spaces for Reflective Practice in Teacher Education
Authors: Garcia Nuria Alonso , Campbell Sarah Elizabeth
Published: November 2023

Reflective practice enables educators to engage in self-examination of personal narratives and potential implicit bias that might impact their engagement with the learning communities they serve. Reflective practice informed by critical pedagogies supports educators in fostering learning spaces that affirm diversity, cultivate intellectual and personal growth, and invite community voices. Reflective practice work is grounded in deep trust, reciprocal mentorship, and a shared commitment to culturally sustaining education. As part of the Reflective Practice in Teacher Education project, the authors designed and discussed teaching for critical consciousness resources and reflective practice modules that allowed PreK-12 educators to delve into identity, implicit biases, culture, privilege, and resilience through a variety of methodologies (including dialogue, eloquent listening, journaling, mindfulness, portraiture).
Living Into Our Shared Commitments
Authors: Arnold Amy , Farley Lisa , Flessner Ryan , Minton Chasadee , Oliver Brandie , Welch Mindy , Williams Felicia
Published: November 2023

This chapter highlights the Diversity, Equity, and Inclusion (DEI) Fellowship Program in the College of Education at Butler University. The chapter examines the work of the fellows as they led professional learning communities (PLCs) focused on DEI related topics. Data include written reflections produced by the fellows as well as survey responses from colleagues who took part in the PLCs. The chapter captures individual stories of the authors as well as a collective story that examines the implementation of the professional learning communities. Successes are captured, and areas for growth are explored.
Relating, Reckoning, and Reconciling
Authors: McTamaney Catherine , Rifkin Eve , Mohyuddin Hasina , Joseph Nicole M.
Published: November 2023

This chapter describes the work of a professional learning community of higher-education faculty and staff launched to support and probe more expansive thinking about issues of equity, diversity, inclusion, and belonging (EDIB). As participant-observers, the authors describe the preparation, enactment, and reflection upon a pilot program using structured protocols to curate opportunities for faculty to engage authentically in EDIB work. Building on research into the development of professional learning communities and the contexts of transformational learning and tempered by the needs for psychological safety in the process, a professional learning community (PLC) of 13 faculty and 3 facilitators was launched to support more expansive thinking about EDIB issues. While most often EDIB efforts to address in higher education are reactive to an inciting event or crisis, this project seeks to create sustainable transformative learning centering inclusion and disrupting systems of dominance and white supremacy in a more proactive way.
Morphometric and meristic traits of giant sea catfish Arius gigas (boulenger 1911) from new Calabar river and Degema River, Rivers State, Nigeria
Authors: Dienye H. E. , Olaniyi O. A. , Nwafili S. A. , Okoro U. , Bamidele N.
Published: November 2023

Morphometric and meristic characters of the Arius gigas species were examined from two study areas (New Calabar and Degema Rivers) for a period of six months in Rivers State, Nigeria. Total of 200 individuals, 100 from each study site, were examined and analyzed. A majority of the values for external morphometric parameters of A. gigas were higher in the New Calabar River than those from Degema River population, with no significant differences exist (p<0.05) across the morphometric parameters except for pre-orbital length, post-orbital length and eye length. The meristic characters revealed variations in the mean values of dorsal fin spine (8.55±0.11 and 7.07±0.38), pectoral fin ray (5.96±0.06 and 4.23±0.26), and pelvic fin ray (14.99±1.21 and 7.51±0.52) in the study. A significant difference was noted in the number of dorsal fin spine (p< 0.05) between the two populations. The mean percentage of the Length of caudal peduncle (LoCP),1st and 2nd dorsal fin (DF), length of interdorsal fin (LoIDF) and length of adipose fin (LoAF) of A. gigas in the New Calabar River were significantly higher (p<0.05) than Degema River. Growth variability for standard length and all external parameters displayed allometric growth of A. gigas from Degema River. Further studies are recommended to corroborate the findings of the two populations using molecular markers for making conservation plans for exploitable A gigas species.
Mitigating infectious disease risks through non-stationary flood frequency analysis: a case study in Malaysia based on natural disaster reduction strategy
Authors: Mat Jan Nur Amalina Mat Jan , Marsani Muhammad Fadhil , Thiruchelvam Loshini , Zainal Abidin Nur Balqishanis , Shabri Ani , Abdullah Sani Sarah A'fifah
Published: November 2023

The occurrence of floods has the potential to escalate the transmission of infectious diseases. To enhance our comprehension of the health impacts of flooding and facilitate effective planning for mitigation strategies, it is necessary to explore the flood risk management. The variability present in hydrological records is an important and neglecting non-stationary patterns in flood data can lead to significant biases in estimating flood quantiles. Consequently, adopting a non-stationary flood frequency analysis appears to be a suitable approach to challenge the assumption of independent and identically distributed observations in the sample. This research employed the generalized extreme value (GEV) distribution to examine annual maximum flood series. To estimate non-stationary models in the flood data, several statistical tests, including the TL-moment method was utilized on the data from ten stream-flow stations in Johor, Malaysia, which revealed that two stations, namely Kahang and Lenggor, exhibited non-stationary behaviour in their annual maximum streamflow. Two non-stationary models efficiently described the data series from these two specific stations, the control of which could reduce outbreak of infectious diseases when used for controlling the development measures of the hydraulic structures. Thus, the application of these models may help prevent biased prediction of flood occurrences leading to lower number of cases infected by disease.
Intention-to-treat versus as-treated versus per-protocol approaches to analysis
Authors: Ahn EunJin , Kang Hyun
Published: November 2023

Randomized controlled trials (RCTs) are considered the most rigorous study design for testing hypotheses and the gold standard for evaluating intervention effectiveness. However, RCTs are often conducted under the assumption of ideal conditions that may differ from real-world scenarios in which various issues, such as loss to follow-up, mistakes in participant enrollment or intervention, and low subject compliance or adherence, may occur. There are various group-defining strategies for analyzing RCT data, including the intention-to-treat (ITT), as-treated, and per-protocol (PP) approaches. The ITT principle involves analyzing all participants according to their initial group assignments, regardless of study completion and compliance or adherence to treatment protocols. This approach aims to replicate real-world clinical settings in which several anticipated or unexpected conditions may occur with regard to the study protocol. For the PP approach, only participants who meet the inclusion criteria, complete the interventions according to the study protocols, and have primary outcome data available are included. This approach aims to confirm treatment effects under optimal conditions. In general, the ITT principle is preferred for superiority and inequality trials, whereas the PP approach is preferred for equivalence and non-inferiority trials. However, both analytical approaches should be conducted and their results compared to determine whether significant differences exist. Overall, using both the ITT and PP approaches can provide a more complete picture of the treatment effects and ensure the reliability of the trial results.
Actions of $\mathfrak{sl}_2$ on algebras appearing in categorification
Authors: Elias Ben , Qi You
Published: November 2023

We prove that many of the recently-constructed algebras and categories which appear in categorification can be equipped with an action of

\mathfrak{sl}_2

by derivations. The

\mathfrak{sl}_2

representations which appear are filtered by tensor products of coVerma modules. In a future paper, we will address the implications of the

\mathfrak{sl}_2

structure for categorification.
Can MRI predict olfactory loss and improvement in posttraumatic olfactory dysfunction?
Authors: Hsieh J W , Lenoir V , Sipione R , Hugentobler M , Daskalou D , Lundström J N , Senn P , Rimmer J , Becker M , Landis B N
Published: November 2023

BACKGROUND: Although most patients with post-traumatic olfactory dysfunction (PTOD) undergo MRI, there is no consensus about its diagnostic or prognostic value. The aims were: 1) to classify the extent of post-traumatic neurodegeneration; 2) to determine its relationship with chemosensory dysfunction (smell, taste, trigeminal); and 3) to establish whether MRI can predict olfactory improvement. METHODOLOGY: We conducted a retrospective cohort study based on a series of 56 patients with PTOD. All patients underwent validated psychophysical tests of their smell, taste, and trigeminal functions, otorhinolaryngologic evaluation, and MRI. An experienced radiologist blinded to patient data evaluated 40 chemosensory-relevant brain regions according to a four-point scale (0=no lesion to 3=large lesion). Follow up data after 4 years (on average) were available in 46 patients. RESULTS:The cluster analysis showed 4 brain lesion patterns that differed in lesion localization and severity. They are associated with diagnostic categories: anosmia, hyposmia and normosmia. Two clusters were highly specific for anosmia (100% specificity)and could accurately predict this condition (100% positive predictive value). No clusters were associated with trigeminal or taste dysfunction. Regarding improvement, 72.7% of patients in the cluster with mild lesions experienced subjective and measurable olfactory improvement whereas this was only the case in 21.7-37.5% of patients with larger lesions. The odds of subjective smell improvement were 5.9 times higher in patients within the milder cluster compared to larger ones. CONCLUSIONS: The analysis of brain lesions in PTOD allows corroboration of smell test results and prediction of subjective and measurable improvement.
О существовании собственных значений трехчастичного дискретного оператора Шрeдингера
Authors: Abdullaev Zhanikul Ibragimovich , Boymurodov Jurabek Khusanovich , Khalkhuzhaev Akhmad Miyassarovich
Published: November 2023

Рассматривается трехчастичный оператор Шрeдингера $H_{\mu,\lambda,\gamma}
(\mathbf K)$, $\mathbf K\in \mathbb{T}^3$, ассоциированный с системой трех частиц (две из них - бозоны с массой $1$ и одна - произвольная с массой $m=1/\gamma<1$), взаимодействующих с помощью парных контактных
потенциалов $\mu>0$ и $\lambda>0$ на трехмерной решетке $\mathbb{Z}^3$. Доказано, что существуют критические значения отношений масс $\gamma=\gamma_{1}$ и $\gamma=\gamma_{2}$ такие, что оператор $H_{\mu,\lambda,\gamma}(\mathbf{0})$, $\mathbf{0}=(0,0,0)$ имеет: для $\gamma\in (0,\gamma_{1})$ по крайней мере одно собственное значение, для $\gamma\in (\gamma_{1},\gamma_{2})$ не менее двух и для $\gamma\in (\gamma_{2}, +\infty)$ не менее четырех собственных значений, лежащих левее существенного спектра при достаточно больших $\mu>0$ и фиксированном $\lambda>0$.
Библиография: 23 названия.
MULHERES NEGRAS E DE BAIXADA QUE PEDALAM: A BICICLETA COMO FACILITADORA PARA O ACESSO À CIDADE EM BELÉM DO PARÁ
Authors: Feitosa Teodoro Mayara , Neves Pereira Airely
Published: November 2023

O artigo em tela objetiva refletir como a bicicleta proporciona o direito à cidade a um grupo de mulheres que incentivam o uso da bicicleta em Belém do Pará. Para isso, foi feito uso dos pressupostos teóricos e metodológicos da etnografia da duração desenvolvida por Ana Luisa Rocha e Cornélia Eckert, trata-se de uma perspectiva que busca compreender as dinâmicas temporais e os processos de transformação em contextos sociais por meio de uma imersão profunda e prolongada no campo de estudo, características da pesquisa antropológica. As mulheres que pedalam conseguem acessar espaços da cidade que antes não eram acessados por ela, seja pela falta de transporte, seja por influência dos discursos violentos da cidade ou até mesmo a falta de dinheiro, assim, a bicicleta surge como a possibilidade delas se apropriarem autonomamente do espaço urbano. Nesse sentido, a mobilidade por bicicleta promove o direito à cidade, a liberdade que a bicicleta proporciona vem a partir da tomada da consciência de opressão, e assim, iniciar a ocupação, participação e a transformação dos espaços públicos, promovendo maior equidade social.
análise sobre a Doutrina do Fascismo e sua contribuição para compreender o movimento de Mussolini
Authors: Schargel Sergio
Published: November 2023

Dos vários materiais discursivos criados por Mussolini no vintênio Fascista, poucos são tão ricos quanto a Doutrina de 1932. Publicada em um momento em que o regime procurava se institucionalizar e “normalizar”, o material é fundamental à historiografia do Fascismo por revelar como Mussolini enxergava o seu próprio movimento/ideologia/regime. Este artigo oferecerá uma análise de conteúdo deste material, na intenção de apreender os principais elementos que o constituem e suas diferenças ou semelhanças em relação a outros momentos do Fascismo. Com a ajuda das teorias de Albert Hirschman e Robert Paxton, será possível contribuir à historiografia sobre o Fascismo, ao iluminar as idiossincrasias da Doutrina, mostrando, na prática, o quanto o movimento/regime se alterou conforme os anos ― o que dificulta, na prática, falar em um Fascismo com características congeladas. Em suma, entender o que o Fascismo dizia sobre si, e o quanto isso dialogava com a prática.
Analysis of the Feasibility of Universal Basic Income in Colombia: A Grounded Theory Study
Authors: Acuña Gómez Johanna Sareth , Jímenez-Barbosa Wilson Giovanni , Hernández Monsalve Juan Sebastián
Published: November 2023

This paper shows the results of research conducted with the objective of knowing the perceptions of people in Colombia about the possibility of receiving a universal basic income, which does not exist thus far in the country. The research question was: how do the social perceptions of Colombians about receiving a UBI allow them to understand the possibilities of developing a public policy that guarantees it? A qualitative methodology of grounded theory was applied by conducting 37 in-depth interviews with adults of all socioeconomic levels, all educational levels and productive working age. The information obtained was coded. The resultant main categories with which the Grounded Theory was built were mistrust in others, hope for a better society, unconditional support, and implementation scenario. It was concluded that, if there is an intention to implement the UBI in Colombia, there must be policies that contribute to changing the mistrust and fear of citizens to receive support from the State by solidarity and equity so that UBI can be assume as a right that contributes to the construction of justice and social welfare.
Sustainability Innovation in Small Medium Enterprises (SMEs): A Qualitative Analysis
Authors: Harsanto Budi , Mulyana Asep , Faisal Yudi Ahmad , Shandy Venny Mellandhia , Alam Muntasir
Published: November 2023

Prior research suggests that today, sustainability is an important key in innovation. While the integration of sustainability into innovation in large enterprises has been widely studied, research on small-medium enterprises (SMEs) is still lacking. The aim of this study is to understand the sustainability innovation practices in SMEs. We interviewed 30 SME owners and managers in Indonesia and analyzed the data using thematic analysis to understand how SMEs practice sustainability innovation. The findings show that sustainability innovation in the form of product innovation is commonly practiced through the use of more environmentally friendly raw materials and packaging materials. As for process innovation, the practices include local sourcing and empowerment of the surrounding community as well as small-scale waste treatment to help reduce the damaging impact on the environment.
The What and How of Essential Thematic Analysis
Authors: Yanto Elih Sutisna
Published: November 2023

Gareth Terry and Nikki Hayfield's book, Essentials of Thematic Analysis, introduces readers to reflexive thematic analysis, a method for analyzing interview and focus group transcripts, qualitative survey responses, and other qualitative data. This method is based on the understanding that we all exist in a context from which we can see and speak. In this way, researchers produce knowledge that represents situated truths and allow them to understand others’ perspectives on a given topic. The book shows how to construct a “positioned reality of the situation” from qualitative data. According to the authors, this method is not a methodology but rather a method; that is, a theoretical framework. They emphasize adaptability and subjectivity and go beyond data summaries to understand underlying structures. This method requires frequent data exploration and re-evaluation. It can be studied by both novices and experts. The method is illustrated with notes, illustration, and examples. This book provides a straightforward, concise, and comprehensive description of the authors’ approach, including its methodological rigor, advantages, and limitations.
LIKOVNO OBLIKOVANjE SRPSKIH KNjIGA U VREME VLADAVINE KRALjA MILUTINA
Authors: Stanojlović Jovana
Published: November 2023

The period of King Milutin’s reign, marked by the strengthening and expan- sion of the Serbian state, is important for the manuscript book, primarily because of its increased production, caused by the building of a larger number of churches and monasteries, but also in artistic terms, due to the frequent appearance of new ornamental motifs. At that time, there was a gradual change in the decoration of manuscript books created in Serbian scriptoriums. Teratological motifs, which will continue to appear sporadically, give way to geometric-intertwined forms. In the adapted style of the books of this period, there are three basic geometric mo- tifs - a circle, a knot and a rhomboid ring that form various decorative surfaces - from very small discrete flags to those that can occupy an entire page. In addition to flags, initials also have a special place. They can be simpler - geometrically or more developed - intertwined. The period of King Milutin’s long reign is also characterized by the codification of liturgical books according to the Jerusalem typikon, which, among other things, led to the fact that books that were once separate (eg, Prophetologion) became part of other liturgical books. This also affects the artistic design of books, because each liturgical book has recognizable places, highlighted with decorative motifs. At this time at the end of the 13th and the beginning of the 14th century, in the long process of creating books, the use of extremely high quality parchment and ink is striking, as evidenced by their current state. Considering that only a small number of those codices that had to exist at that time have been preserved, for the sake of a more complete idea of their illumina- tion at that time, quite discreet decorations are included in the research. The illu- mination of Serbian books, as well as the entire artistic creation in the considered period, developed within the framework of the Byzantine cultural, spiritual and aesthetic circle. On some pages of the code, however, the original solutions of talented Serbian illuminators and calligraphers are noticeable. This primarily re- fers to the intertwined geometric-floral style, which will reach its full expression in rich compositional solutions during the 14th century.
MANASTIR KRUPA: ZADUŽBINA IZ VREMENA KRALjA MILUTINA
Authors: Orlović Snježana
Published: November 2023

The Krupa Monastery belongs to the Eparchy of Dalmatia. According to the records made in the past few centuries, this monastery was founded in 1317, with the help of King Milutin, by monks from Bosanska Krupa. The fact that this is not just a legend is confirmed by the historical and political circumstances in this area. In the hitherto uninhabited areas, during the reign of Ban Mladen Šubić, at the end of the 13th century, Serbs began to settle. This area was of great importance for Nemanjić and the area over which the Serbian state exerted influence. Serbian rulers king Stefan Dečanski and Tsar Dušan also paid attention and material assistance to the Krupa Monastery. When the Turks ruled Dalmatia, they confirmed to the Krupa monks the right to enjoy the mentioned lands. The Serbian despots of Branković family from Srem, who gave the monastery a "charter" in 1494, also contributed to its renewal. The year 1502 will be the beginning of the centuries of suffering, but also a series of renewals. Today, the church has the basis of a developed inscribed cross with a dome on pendants, which are supported by semicircular vaults. In the 19th centurie, several important construction projects took place, and then the entire monastery complex was formed.
Association Between Erythrocyte Indices and Covid-19 Severity
Authors: Axel Ruslie Geraldo , Suwasanti Niluh , Darmadi Epriyanto T , Tahalele Paul L , Dian Novita Bernadette
Published: November 2023

Rapid oxygen desaturation has been widely reported in sufferers of Coronavirus Disease (COVID-19) with severe and critical severity. The latest scientific evidence shows that this virus can interact with erythrocytes and disrupt the function of hemoglobin as an oxygen transporter. This study aims to analyze the relationship between the erythrocyte index and the severity of COVID-19 sufferers. This research is a cross-sectional study of 120 confirmed COVID-19 sufferers at the PHC Surabaya hospital. This research was conducted from January 2021 to July 2021. This research data was collected from electronic medical records at the Primasatya Husada Citra (PHC) Hospital in Surabaya. Patients in this study were categorized based on the degree of severity into mild-moderate and severe-critical. Statistical analysis was carried out using the Spearman rank correlation test. There is a decrease in the erythrocyte index value in patients with critical severity. Based on the Spearman rank correlation test, a significant correlation with weak correlation strength was found for MCV (r = -468, p=0.000), MCH (r = -337, p=0.000), and MCHC (r = -203, p=0.026 ). This research shows that there is a significant correlation. However, the strength of the correlation is weak, so this parameter cannot be used as a predictor to assess the prognosis and severity of sufferers. Further research is needed for better knowledge regarding COVID-19 and erythrocytes.
The Impact of Corporate Social Responsibility on Financial Performance: The Case of Internet-based Enterprises in China
Authors: Zandi Gholam Reza
Published: November 2023

"With the development of the economy and society, enterprises are no longer just profit organizations. They need to meet the demands of people to fulfill their social responsibilities. The development of Corporate Social Responsibility in China has only been more than a decade, and it is still in the initial exploration stage. Most companies initially adopted a wait-and-see attitude towards it. This article will take the perspective of listed internet companies in China and construct a social responsibility evaluation index system to empirically analyze the relationship between social responsibility and financial performance of internet-based companies. It will explore whether the cost of Corporate Social Responsibility will have a negative impact on their economic benefits. Based on this, it will help internet-based companies correctly understand the important position of social responsibility in their management system and enhance their awareness of actively taking social responsibility."
Anesthesia Options for Pediatric Endoscopy: A Review of Intravenous Sedation and General Anesthesia
Authors: Alkhazal’eh Sana’a
Published: November 2023

Gastrointestinal (GI) endoscopy has emerged as an indispensable tool for the assessment and management of GI disorders. Intravenous (IV) sedation and General Anesthesia (GA) are both employed to alleviate patient discomfort and ensure amnesia during these procedures. Essential aspects of both methods include vigilant monitoring of consciousness levels, pulmonary ventilation, oxygenation and hemodynamics.

While GI endoscopy is generally regarded as safe, there is a potential for complications. This is particularly noteworthy in the context of pediatric patients. Raising awareness of the potential complications linked to sedation during GI endoscopy in children and involving anesthesiologists in their care is pivotal to ensuring safety. Several risk factors for complications were identified, including younger age, higher ASA (American Society of Anesthesiologists) class (indicating more severe health conditions) and the use of IV sedation.

Documented adverse events encompassed issues such as inadequate sedation, diminished oxygen saturation, airway blockages, episodes of apnea necessitating bag-mask ventilation, patient agitation, occurrences of bleeding and cases of organ perforation. Statistical analysis revealed that complications were less frequent when GA was used (1.2%) compared to IV sedation (3.7%). Furthermore, IV sedation was found to be independently linked to a 5.3% higher risk of cardiopulmonary complications compared to GA. Consequently, GA can be considered a safer and more efficacious choice in providing comfort and amnesia during GI endoscopy.
Personalisme Karol Wojtyła
Authors: Lesomar Antonius Alex
Published: November 2023

Tulisan ini bertujuan untuk mempresentasikan kekhususan personalisme Karol Wojtyła. Personalisme yang dikembangkan oleh Wojtyła adalah personalisme substantial. Personalismenya adalah kombinasi dari pendekatan metafisika dan fenomenologi. Melalui kedua pendekatan ini ditemukan bahwa manusia adalah suppostium sekaligus sebagai personal being (pengada personal).  Kekhususan dari manusia sebagai personal being yaitu ia menjadi sumber atau subjek dari eksistensinya dan semua bentuk dinamisme (apa yang terjadi pada manusia dan tindakan sadar) yang pantas bagi manusia. Person tidak hanya sebagai subjek dalam arti objektif, dalam ranah metafisika, tetapi juga subjek dalam arti subjektif atau subjek dari pengalaman, dalam ranah fenomenologi, dimana ia menyadari dan mengalami dirinya sebagai subjek.  Dan secara khusus dalam dan melalui tindakan sadar sebagai dinamisme khas person ditampakkan nilai personalistik, dimana dalam dan melalui tindakan ia memenuhi dirinya dalam arti moral sebagai seorang yang baik atau jahat. Untuk mencapai maksud dari penulisan ini maka metode yang digunakan yaitu analisa teks dan ekplanasi.
EUTHANASIA DALAM PERSPEKTIF MORAL DAN AGAMA: SUATU TINJAUAN REFLEKTIF TERHADAP KODRAT MANUSIA DALAM TERANG GAUDIUM ET SPES
Authors: Nifanngelyau Martinus , Koisin Edoardus
Published: November 2023

AbstrakPenelitian ini bertujuan untuk mengetahui bagaimana euthanasia dalam perspektif moral dan agama: Suatu Tinjauan Reflektif Terhadap Kodrat Manusia   Dalam Terang Gaudium Et Spes. Penelitian ini mengunakan jenis pendekatan library research atau riset kepustakaan untuk euthanasia dalam perspekrif moral dan agama yang dimana kajian tentang euthanasia memiliki makna untuk mengakhiri hidup dengan cara mudah, tanpa rasa sakit atau kematian yang baik. Dari sudut pandang etika/moral dan agama, euthanasia berhadapan dengan suatu prinsip yang sangat mendasar, yaitu keharusan menghormati kehidupan manusia bagaimana pun keadaannya, bahkan seandainya ia berada dalam keadaan klinis “status vegetatif” sekalipun. Untuk melihat euthanasia dalam perspektif moral terlihat jelas bahwa euthanasia sangat bertentangan dengan dengan moral, yang dimana moral merupakan nilai-nilai dalam kehidupan yang mengatur tentang tindakan dan tingkah laku baik seseorang maupun kelompok dalam masyarakat. Oleh karena itu menghilangkan nyawa orang atau membunuh merupakan suatu pelanggaran terhadap nilai-nilai moral, dan tindakan itu tidak dapat dibenarkan dan tak dapat diterima dengan alasan dan dalam keadaan apapun. AbstractThis study aims to find out how euthanasia is from a moral and religious perspective: A Reflective Review of Human Nature in the Light of Gaudium Et Spes. This research uses a type of library research approach or library research for euthanasia in a moral and religious perspective where the study of euthanasia has the meaning of ending life in an easy way, without pain or good death. From an ethical/moral and religious point of view, euthanasia deals with a very basic principle, namely the obligation to respect human life no matter what the circumstances, even if he is in a clinical state of "vegetative status". To see euthanasia in a moral perspective it is clear that euthanasia is very contrary to morality, where morals are values in life that govern the actions and behavior of both individuals and groups in society. Therefore killing people or killing is a violation of moral values, and that action cannot be justified and cannot be accepted for any reason and under any circumstances.
TELAAH FAKTOR-FAKTOR PENGARUH STUKTUR MODAL PERUSAHAAN BLUE CHIP NON KEUANGAN DI BEI
Authors: Kartika Yuni , Mahaputri Rizki Kurnia , S. Siregar Bernardus Wishman
Published: November 2023

This study aims to determine the effect of firm size and liquidity on capital structure partially and simultaneously. This research was conducted because there were inconsistencies in the results of previous studies. The data used is secondary data using a sample of 67 samples of Non-Financial Blue Chip companies listed on the Indonesia Stock Exchange in 2017-2020. Sampling was carried out using purposive sampling. This study uses a quantitative approach and the analysis technique used is multiple linear regression analysis. The results showed that the independent variables of firm size and liquidity had an effect on capital structure both partially and simultaneously.Keywords: Company Size, Liquidity, Capital Structure, Blue Chip, Non-financial ABSTRAKPenelitian bertujuan mengetahui pengaruh ukuran perusahaan dan likuiditas terhadap strukktur modal secara parsial dan simultan. Penelitian ini dilakukan karena terdapat ketidakkonsistenan hasil dari penelitian terdahulu. Data yang digunakan adalah data sekundur menggunakan sampel sebanyak 67 sampel perusahaan Blue Chip Non Keuangan yang terdaftar di Bursa Efek Indonesia pada tahun 2017-2020. Pengambilan sampel dilakukan dengan menggunakan purposive sampling. penelitian ini menggunakan pendekatan kuantatif dan teknik analisis yang digunakan adalah analisis regresi linier berganda. Hasil penelitian menunjukan variabel independen ukuran perusahaan dan likuiditas berpengaruh terhadap strukktur modal baik secara parsial dan maupun simultan.Kata Kunci : Ukuran Perusahaan, Likuiditas, Struktur Modal, Blue Chip, Non Keuangan
Écrire l’histoire de la fiscalité antique : un défi insurmontable ?
Authors: GIRARDIN Michaël
Published: November 2023

Résumé Le renouveau historiographique concernant la fiscalité antique nécessite de prendre le temps d’une réflexion épistémologique. Les défis à surmonter pour travailler sur ce domaine d’étude sont nombreux. La lecture croisée des articles de ce dossier fournit quelques pistes pour repenser le rapport des historiens aux travaux passés, aux sources, ainsi que la méthodologie la plus adéquate. La transdisciplinarité et l’attention portée aux contextes de production des principales références bibliographiques sont mises en avant comme des éléments indispensables pour progresser sans dépendre excessivement d’héritages historiographiques éventuellement discutables aujourd’hui. Title: Writing the History of Ancient Taxation: An Impossible Challenge? The historiographical renewal concerning Ancient taxation requires taking the time for epistemological thoughts. There are many challenges to overcome in order to work on this field of study. The cross-reading of the papers in this dossier provides some leads for rethinking the relationship of historians to past works, to sources, as well as the most appropriate methodology. Transdisciplinarity and the attention paid to the contexts of production of the main bibliographical references are put forward as essential elements for progress without depending excessively on possibly questionable historiographical legacies.
Vectigalia nervos esse rei publicae? Three Case-Studies on Ancient Framing of Taxes in the Roman Republic beyond Modern Fiscal Discourses
Authors: GÜNTHER Sven
Published: November 2023

Résumé

Titre : Vectigalia nervos esse rei publicae? La perception de l’impôt dans la République romaine : trois études de cas, pour dépasser les discours modernes sur la fiscalité

Avec l’essor de la New Fiscal History, les modèles de comportement de l’État prédateur et l’application des études de la culture politique, le débat sur la nature de la fiscalité romaine a repris de l’ampleur. Tandis que des sujets importants comme les institutions du régime fiscal romain, les relations entre ses agents et les contribuables, ainsi que le caractère concurrentiel de l’élite romaine dans le domaine des finances publiques ont été renouvelés par ces approches, le caractère discursif des sources a rarement été interrogé et analysé. Pourtant, les écrits d’auteurs romains d’époque républicaine, tels que Cicéron, César et Salluste, de même que les documents historiographiques des époques ultérieures, font un lien entre les informations fiscales et les discours politiques, sociaux, économiques, et même moraux. Dès lors, l’objectif de ce texte est de révéler, avec trois études de cas, les paradigmes (frameworks) dans lesquels les impôts étaient interprétés et présentés, puis de confronter ces paradigmes aux interprétations actuelles afin de démontrer combien les auteurs anciens et modernes intègrent leurs conceptions de la fiscalité romaine d’époque républicaine dans un cadre d’analyse qui leur est propre.

Abstract

With the rise of New Fiscal History, models of predatory state behavior, and the application of political culture studies within the field, debate over the character of Roman taxation has regained momentum. While important topics such as the institutions of the Roman tax regime, the relationship of its actors to taxpayers, and the competitive character of the Roman elite in the field of public finances have been studied anew within these frameworks, the discursive character of the sources has rarely been questioned and analyzed. Yet, the writings of contemporary authors such as Cicero, Caesar, and Sallust, as well as historiographic records from later periods do connect fiscal information with political, social, economic, or moral discourses. Hence, the task of this paper is to reveal the ancient frameworks within which taxes were perceived and presented in three case studies, and to juxtapose these with current debates in order to demonstrate the extent to which ancient and modern authors frame(d) perceptions of Roman taxation in the Republican period.
Héroïque jeunesse, victoire éclose : à propos d’un combat de pygmées et de grues (retour sur l’hydre du Louvre F 44)
Authors: MACKOWIAK Karin
Published: November 2023

Résumé

L’analyse iconographique de l’hydrie du Louvre F 44 qui figure le mythique combat des pygmées contre les grues, rapporté par ailleurs dans l’Iliade, pose de nombreuses questions à l’historien, notamment celles de la relation entre les scènes du vase et la réalité sociale et culturelle de l’Athènes d’époque archaïque. La mise en scène originale du mythe justifie des hypothèses relatives à la présence d’un discours sur l’éducation des jeunes gens au VIe s. av. J.-C. Comment l’image est-elle susceptible de construire ce discours ? Quelle(s) lecture(s) l’historien peut-il en faire ?

Abstract

Title: Heroic Youth, Blossoming Victory: About a Hydria in the Louvre Museum (F 44)

An hydria in the Louvre Museum (F 44), figurating the epic – and homeric – tale of the pygmies and cranes, proposes an interesting field of research for the historian. Among the many questions raised by this archaic vase painting are the relationships between pictures and the social context possibly imbedded in them, more precisely an educational discourse concerning athenian youth in the VIth century B.C. How do finally the pictures order this discourse ? Which kind of readings or significations can they afford to the historian ?
Tolerância à corrupção em democracias latino-americanas
Authors:   , Lieberenz Thaysa Viana Almeida de
Published: November 2023

A corrupção é uma conduta - ou prática - que se desvia das expectativas padronizadas no desempenho das funções do poder confiado. O que é ou não percebido como corrupção varia entre os indivíduos, no espaço e no tempo. Sempre haverá um certo grau de permissividade em relação à corrupção na sociedade. Esta dissertação concentra-se em compreender os elementos que condicionam a tolerância à corrupção, em nível individual, nas democracias latino-americanas. Para tanto, calculou-se um modelo probit ordenado, usando dados do Latinobarômetro de 2020. Os resultados indicam que os homens, em média, são mais propensos a ter menor tolerância à corrupção do que as mulheres; que indivíduos com menor nível de escolaridade têm maior probabilidade de serem mais tolerantes à corrupção; e que níveis mais elevados de prática religiosa tendem a estar associados a atitudes mais duras em relação à corrupção. Os resultados também evidenciam que os funcionários das empresas privadas têm maior probabilidade de serem mais tolerantes do que os de empresas públicas. No que se refere à percepção da extensão da corrupção, os indivíduos que acreditam que a corrupção aumentou ou aumentou muito no ano de 2020, tendem a ser menos tolerantes à corrupção e que aqueles que estão mais satisfeitos com a democracia mostram uma tendência menor de tolerar a corrupção. Confiar em muitas instituições governamentais - nacionais e internacionais - também está associado a uma menor tolerância à corrupção, resultado semelhante para indivíduos que preferem uma sociedade mais livre. Pode-se perceber que, ao se comparar com ano de 2016, os condicionantes da tolerância à corrupção se mantiveram, à exceção do resultado por sexo. Este estudo fornece evidências relevantes sobre os determinantes individuais da tolerância à corrupção nas democracias da América Latina e, portanto, nos ajuda a compreender por que a corrupção é mais resistente em algumas sociedades do que em outras. Palavras-chave: Tolerância à corrupção. Latinobarômetro. Probit ordenado.
PENGARUH KONSENTRASI EKSTRAK KAYU SECANG PADA PEMBUATAN SABUN ANTIBAKTERI TRANSPARAN
Authors: Kalla Ruslan , Putriani Eka , Derwan Ilsa Safitri , Wiyani Lastri
Published: November 2023

Sabun antiseptik yang ada di pasaran selama ini menggunakan zat aktif sintetik untuk membunuh bakteri. Tujuan dari penelitian ini adalah mengetahui pengaruh penambahan ekstrak kayu secang terhadap daya hambat auerus pada sabun transparan dan mengetahui mutu sabun tranparan dari ekstrak kayu secang sesuai standar nasional indonesia (SNI 06-3532-2016). Proses pembuatan sabun menggunakan metode panas dengan waterbath sebagai medianya. Minyak kelapa murni (VCO) dipanaskan dengan waterbath. Masukkan asam stearat, lalu aduk hingga homogen. Kemudian masukkan larutan NaOH 30%. Setelah itu masukkan etanol 96%, gliserin, sirup gula (gula pasir+akuades yang dicairkan terlebih dahulu), coco-DEA terlebih, NaCl, dan fragrance oil kemudian aduk hingga tercampur sempurna. Turunkan  suhunya hingga mencapai ±50°C kemudian masukkan ekstrak kayu secang kemudian tuangkan ke dalam cetakan silikon dan diamkan selama 24 jam.  Setelah 24 jam, sabun dilakukan proses curing selama ±3 minggu. Pada penelitian ini kemampuan sabun dari ekstrak kayu secang untuk menghambat bakteri Staphylococcus aureus pada sabun transparan diperoleh diameter zona hambat tertinggi pada variasi penambahan 2% ekstrak kayu secang yaitu 13,3 mm. Kadar air tertinggi pada F4 yakni penambahan 2% ekstrak kayu secang dengan nilai 3,8% dan kadar air terendah pada F1 yakni tanpa penambahan ekstrak kayu secang dengan nilai 2,63%
OPTIMASI PEMELIHARAAN PEMANTAUAN SUHU KANDANG DOC AYAM BROILER DENGAN SENSOR LM35 DAN TEKNOLOGI KOMUNIKASI BLUETOOTH
Authors: Sriwati Sriwati , M Saripuddin , Fathurrahman Muhammad , Khaidir Muhammad
Published: November 2023

Suhu kandang mengalami perubahan suhu sehingga perlu dibuat rancangan otomatis. Tujuan penelitian yaitu merancang sistem otomatis yang mampu mengatur suhu pada kandang ayam broiler. Metode penelitian yang digunakan sistem Arduino Uno sebagai kontrol utama. Untuk mengukur suhu di sekitar kandang menggunakan sensor LM35. Berdasarkan nilai suhu yang terdeteksi menggunakan sensor LM35, Arduino akan mengontrol lampu dan relay bertindak sebagai saklar untuk mengatur panas lampu. Hasil pengujian menunjukkan bahwa sensor suhu bekerja dengan baik, tingkat error sebesar 1,69%. Secara keseluruhan, sistem pemanas kandang ayam bekerja dengan baik dan memenuhi harapan. Kesimpulan perancangan sistem sudah sesuai dengan kebutuhan kandang DOC ayam broiler.
RT-qPCR Protocol Optimization Assessment with Propidium Monoazide for Viable and Non-Viable Pathogen Detection
Authors: Mariam Sajid  , Mohamed Askar  , Roger Bayston
Published: November 2023

Real time PCR or RT-qPCR (including reverse transcriptase PCR) is a gold standard in diagnostic testing for pathogens such as bacteria and viruses that contain RNA or DNA for amplification. As a validated molecular assay technique, RT- qPCR has been instrumental in microbial detection because of its high throughput, quantification of DNA or RNA samples as well as quick turnaround especially when compared with culturing methods that can take multiple days to generate result. While the advancement of PCR has had significant impact for diagnosis of diseases such as COVID- 19through its high sensitivity and specificity, the test also brings with it its own challenges of false positive and false negative results. This is normally attributed to PCR's susceptibility to contamination or inhibitors. However, there are other conditions like DNA extraction techniques and protocols in PCR methodology that can impact the accuracy of the PCR results as well. This paper, therefore, aims to synthesize factors that contribute to false positive and negatives in PCR results, improvements to protocols that includes the use of DNA intercalating dyes such as Propidium Monoazide (PMA) in PCR assay to improve DNA extraction and discuss the importance of an optimized PCR assay for diagnostic testing efficacy from a social and economic standpoint.