bluuebunny/crossref_metadata_2025 huggingface dataset:
PAPER RETRACTION Amir Monfaredan et al. “Designing a microchip for exosome…”, RENSIT, 2024, 16(2):223-238.
Authors:   Kotel'nikov Institute of Radioengineering and Electronics of RAS, Grachev Vladimir I.
Published: August 2024

RETRACTED (duplicate), 06/15/2024: article by Amir Monfaredan, Fakher Rahim, Kojobekov K.G., Gholamreza Tavusidan, Mohammad Hossein Modarressi, Alaviesadat Hosseininasab, Ali-Akbar Aghajani-Afrouzi, Mahdi Shafi Sabet, Elahe Motevaseli. Microarray for exosome isolation with the possibility of simultaneous impregnation with imatinib: in vitro analysis. Publication: RENSIT: Radioelectronics. Nanosystems. Information Technologies, 2024, 16(2)223-238. DOI: 10.17725/rensit.2024.16.223. Topic: Medical Physics. Initiator of the retraction – Amir Monfaredan, ORCID: 0009-0008-2016-0198. Grounds for retraction of the article: violation of publication ethics by its authors – duplication in another journal – Russian Open Medical Journal, 2024. Volume 13. Issue 1 (March). Article CID e0104. DOI: 10.15275/rusomj.2024.0104. Date of the decision on retraction – 15.06.2024.
Acoustic properties of aluminum-polystyrene composite
Authors:   Институт радиотехники и электроники им. В.А. Котельникова РАН, Смирнов Андрей В. , Анисимкин Владимир И ,   Институт радиотехники и электроники им. В.А. Котельникова РАН
Published: August 2024

В работе представлены результаты экспериментальных исследований акустических свойств композита алюминий-полистирол со связностью 0-3. Получены зависимости скорости и затухания продольных объемных акустических волн (ОАВ) в композите на частоте 17 МГц, а также его плотности и акустического импеданса, от объемного содержания в нем частиц алюминия, в диапазоне 0-80%. Показано, что увеличение объемной доли частиц наполнителя в составе композита алюминий-полистирол приводит к существенным изменения его физических свойств - плотности и акустического импеданса - почти в 2 раза, скорости продольных волн – на 17 % и акустического затухания – в 25 раз. Скорость и затухание являются, соответственно, наименее и наиболее чувствительными параметрами к составу композита. Зависимости имеют нелинейный характер, это связано возникновением воздушных включений, межзеренным взаимодействием частиц алюминия и, как следствие, ухудшением межфазного взаимодействия и структурной организации композитного материала
Determination of viscosity and dielectric constant of liquids using the equivalent circuit method using a resonator with a lateral electric field
Authors:   Институт радиотехники и электроники им. В.А. Котельникова РАН, Саратовский филиал, Бородина Ирина А. , Зайцев Борис Д. ,   Институт радиотехники и электроники им. В.А. Котельникова РАН, Саратовский филиал, Теплых Андрей А. ,   Институт радиотехники и электроники им. В.А. Котельникова РАН, Саратовский филиал, Семёнов Александр П. ,   Институт радиотехники и электроники им. В.А. Котельникова РАН, Саратовский филиал
Published: August 2024

В работе представлен метод определения вязкости и диэлектрической проницаемости жидкости с использованием метода эквивалентных схем. Были найдены параметры эквивалентной схемы Мэзона для пьезоэлектрического резонатора с поперечным электрическим полем из керамики ЦТС-19. Измерены частотные зависимости реальной и мнимой частей электрического импеданса резонатора, нагруженного образцами жидкости с различной вязкостью и диэлектрической проницаемостью. Был проведен фиттинг теоретических частотных зависимостей реальной и мнимой частей электрического импеданса резонатора, нагруженного смесями “вода - изопропиловый спирт” и “вода - глицерин”, к измеренным зависимостям. В результате были построены зависимость диэлектрической проницаемости жидкости от дополнительной емкости (определена из схемы Мэзона) и зависимость поперечной вязкости жидкости от мнимой части механического импеданса жидкостной нагрузки (определена из схемы Мэзона). Эти зависимости можно использовать в качестве калибровочных кривых для определения диэлектрической проницаемости и вязкости.
Hydrogen bonds spatial grids in liquids and solutions
Authors:   Институт общей и неорганической химии им. Н.С. Курнакова РАН, Родникова Маргарита Н.
Published: August 2024

Представлен обзор исследований автора проблемы трехмерной сетки водородных связей в жидкостях и растворах. Выявлены основные свойства пространственной сетки: устойчивость, лабильность, упругость и скоррелированность разных видов движения частиц, образующих сетку. Представлены методы и результаты описания и исследования трехмерных сеток. Показана определяющая роль пространственных сеток водородных связей в широком спектре жидкостных проблем биологии, физики и химии, в прикладной и фундаментальной науке. Предложено выделить жидкости с пространственной сеткой водородных связей в отдельный класс растворителей, во главе которого стоит вода.
Triplet superconducting correlations of hybrid mesa-structure with bi-layer ferromagnetic interlayer
Authors:   Институт радиотехники и электроники им. В.А. Котельникова РАН, Константинян Карен И. , Овсянников Геннадий А. ,   Институт радиотехники и электроники им. В.А. Котельникова РАН, Кислинский Юлий В. ,   Институт радиотехники и электроники им. В.А. Котельникова РАН, Петржик Андрей М. ,   Институт радиотехники и электроники им. В.А. Котельникова РАН
Published: August 2024

меза-структуре Sd/F1F2/S, состоящей из эпитаксиальных плёнок Sd купратного сверхпроводника YBa2Cu3O7-δ и F1F2 двухслойной ферромагнитной прослойки.В качестве верхнего сверхпроводящего электрода S использовалась плёнка металлического Nb, нанесённая поверх тонкого защитного слоя Au. Дальнодействующая триплетная компонента сверхпроводящих корреляций возникает при использовании в качестве ферромагнитных материалов F1 рутената стронция SrRuO3 и F2 манганита La0.7Sr0.3MnO3 с неколлинеарными намагниченностями и обнаруживается до толщин F1F2 прослойки d = 53 nm. При этом сверхпроводящий ток отсутствует как в случае прослойки из одиночного манганита (La0.7Sr0.3MnO3 или La0.7Ca0.3MnO3), так и SrRuO3 с минимизированными толщинами, ограничиваемыми возникновением проколов. В работе обсуждаются также влияние магнитного поля на транспортные зависимости сверхпроводящего тока и возникновение второй гармоники в ток-фазовой зависимости.
Structural Features, Electronic and Spin Transport in Epitaxial Thin Films of Iridates
Authors:   Институт радиотехники и электроники им. В.А. Котельникова РАН, Байдикова Виктория А. , Дубицкий Никита В. ,   Институт радиотехники и электроники им. В.А. Котельникова РАН, Москаль Иван Е. ,   Институт радиотехники и электроники им. В.А. Котельникова РАН, Овсянников Геннадий А. ,   Институт радиотехники и электроники им. В.А. Котельникова РАН, Петржик Андрей М. ,   Институт радиотехники и электроники им. В.А. Котельникова РАН, Ульев Георгий Д. ,   Институт радиотехники и электроники им. В.А. Котельникова РАН, Константинян Карен И. ,   Институт радиотехники и электроники им. В.А. Котельникова РАН, Кислинский Юлий В. ,   Институт радиотехники и электроники им. В.А. Котельникова РАН, Шадрин Антон В. ,   Институт радиотехники и электроники им. В.А. Котельникова РАН
Published: August 2024

Разработана методика получения высококачественных эпитаксиальных пленок иридата стронция методом высокочастотного катодного распыления на подложки из титаната стронция и галата ниодима. С помощью рентгеновской дифракции изучены структурные особенности и влияние релаксации механических напряжений в тонких пленках, вызванных различием размеров решетки пленки и подложки. Из анализа дифракционных данных установлено, что в пленке наблюдается деформация параметра решетки. Это свидетельствует о возникновении напряжений, обусловленных несоответствием параметров решетки пленки и подложки, что приводит к неоднородной релаксации напряжений в пленке. Исследованы электронные транспортные параметры тонких пленок и возбуждение спинового тока в гетероструктурах SrIrO3/La0.7Sr0.3MnO3.
A Roadmap to Seamless Connectivity via the Integration of 5G and Radio Access Networks
Authors:   Университет Аль-Китаб, Мохаммед Али Али , Шакор Пштиван ,   Университетский колледж Аль-Калама, Абдулла Салам Х. ,   Университетский колледж Аль-Нухбы, Мохаммед Марван А. ,   Университет знаний, Инженерный колледж, Аббас Саад Д. ,   Университетский колледж Аль-Рафидаин, Салман Хайдер М. ,   Университетский колледж Аль-Турат, Мохаммед Мохаммед А. ,   Университетский колледж Альнур, Калматов Романбек К. ,   Ошский государственный университет
Published: August 2024

Использовался смешанный подход для оценки эффективности и осуществимости внедрения 5G-RAN (fifth Generation-Radio Access Network). Это достигается за счет интеграции количественных данных пилотных исследований с качественным анализом литературы. Результаты показывают, что использование технологии 5G приводит к существенному улучшению скорости передачи данных, уменьшению задержек, повышению надежности сети, масштабируемости и снижению задержек. Выявлено несколько препятствий, в том числе значительные затраты, связанные с инфраструктурой, проблемы совместимости и проблемы безопасности. Интеграция 5G и RAN обеспечивает реальный подход к обеспечению бесперебойной связи, что приводит к значительным преимуществам во многих отраслях.
ОТЗЫВ СТАТЬИ Амир Монфаредан и др. «Разработка микрочипа для экзосомы…», RENSIT, 2024, 16(2):223-238.
Authors:   Институт радиотехники и электроники им . В.А. Котельникова РАН, Грачев Владимир И.
Published: August 2024

ОТМЕНЕНА (дубликат), 15.06.2024: статья Амира Монфаредан и др. Микрочип для выделения экзосом… Издание: РЭНСИТ, 2024, 16(2)223-238. DOI: 10.17725/rensit.2024.16.223. Тема: Медицинская физика. Инициатор отзыва – Амир Монфаредан, ORCID: 0009-0008-2016-0198. Основания для отзыва статьи: нарушение авторами публикационной этики – дублирование в другом журнале – РОМЖ, 2024. Том 13. Выпуск 1 (март). CID статьи e0104. DOI: 10.15275/rusomj.2024.0104. Дата принятия решения об отзыве – 15.06.2024.
Investigation of the modal frequency of a long-span suspension bridge under multiple environmental conditions
Authors: Qin Yazhou , Xu Jiancong
Published: August 2024

This study employs advanced techniques, namely the improved multi-synchrosqueezing transform (IMSST) and the Fourier synchrosqueezed transform (FSST), to extract the instantaneous frequency of the Humber Bridge, in the UK, in operational conditions. First, a brief overview of the relevant
theories behind the techniques used is provided. These techniques are then applied to track the instantaneous frequencies within the monitored vertical acceleration data of the bridge. The instantaneous frequencies extracted by both techniques are verified against each other. The investigation
further encompasses the development of three distinct regression models: a simple regression model, an expanded regression model and a regression model based on principal component analysis (PCA). The efficacy of the PCA-based model is scrutinised by generating and testing datasets that mirror
the monitored data, with the Kolmogorov-Smirnov (KS) test confirming their validity. The findings of this research indicate a statistically significant inverse relationship between modal frequency and acceleration intensity. Furthermore, by incorporating wind effect considerations into the
regression analysis, the R-squared values in both the expanded and PCA-based models exhibit substantial improvements. This demonstrates the performance of the enhanced model in capturing the dynamics of the bridge. The robustness of the PCA-based model is further corroborated by its performance
during testing, proving its potential as a reliable tool in structural health monitoring (SHM).
An extraction method for early fault features of rolling bearings based on resonance sparse signal decomposition and non-convex second-order total variation denoising
Authors: Xu Changjie , Ding Jun , Wang Caihong , Zhang Min
Published: August 2024

A primary challenge in the field of fault diagnosis is extracting weak fault characteristics of bearings under large background noise and non-stationary conditions. Due to significant noise interference in the signals of rolling bearings, resonance sparse signal decomposition (RSSD)
cannot efficiently extract the transient impact components in the early failure stage and the total variation denoising (TVD) method distorts signal waveforms. In this study, a combined extraction method for early fault features of rolling bearings based on RSSD and non-convex second-order
total variation denoising (NCSOTVD) is proposed. Firstly, a non-convex function is introduced to define the regularisation term in the second-order TVD method, and the regularisation parameter and the convexity parameter in the NCSOTVD method are respectively screened using the noise standard
deviation and the permutation entropy value to enhance the impact characteristics of signals and induce signal sparsity. The NCSOTVD model is solved using the optimisation-minimisation algorithm, so as to achieve noise reduction and feature enhancement of the vibration signals. Then, the low-resonance
components of RSSD are denoised using the NCSOTVD method to highlight periodic pulse signals and extract the fault features of the rolling bearings. The simulation results and experimental data show that the method largely suppresses the noise interference, highlights the fault characteristics
and reduces the problems of waveform distortion and poor sparsity of the TVD method in the denoising process.
ThermalTrend: a tool for organising and analysing thermal images
Authors: Parrany A M , Dayyani D , Rahimzadeh M
Published: August 2024

Infrared thermography (IRT), as a non-contact condition monitoring (CM) technique, measures the temperature distribution of machines and components to detect anomalous thermal behaviour. It is usually considered as a complementary technique and nowadays is used in a wide variety of
industrial applications. In this paper, two commonly used criteria to assess the condition of machines based on the infrared thermography technique, ie absolute and relative temperature criteria, are represented. Then, the importance of the temperature trend in condition monitoring and fault
diagnosis of machines and components is described. The ThermalTrend software, which was developed in the Condition Monitoring Unit, Smelting Department, Sarcheshmeh Copper Complex in Rafsanjan, Iran, is introduced and its most important and unique features are discussed. This software package
helps thermographers to organise thermal images and provides the temperature trends of machines and components that are under regular monitoring. Finally, some industrial case studies on the usefulness and applicability of the infrared thermography technique and the ThermalTrend software are
reported.
Bearing fault diagnosis method based on recurrence plot and improved EfficientNetV2-S
Authors: Cai Chaozhi , Ma Jie , Ren Jianhua , Xue Yingfang
Published: August 2024

The non-linear and non-stationary characteristics of vibration signals in rolling bearings make it difficult to accurately extract fault features. In addition, traditional fault diagnosis methods cannot fully explore the correlation characteristics between time-series of fault signals.
To address the aforementioned issues, this paper introduces a recurrence plot (RP) coding technique into the field of fault diagnosis and proposes a bearing fault diagnosis method based on RP and the improved EfficientNetV2-S. Firstly, the method uses the RP coding technique to convert one-dimensional
vibration signals into two-dimensional time-frequency images as inputs to the neural network. Then, the number of layers in the EfficientNetV2-S network is optimised by a non-linear attenuation strategy to reduce network parameters and improve the recognition speed. Finally, the attention
mechanism is modified and the variable load dataset is constructed for training to improve the feature extraction ability and generalisation performance of the model. To verify the effectiveness of the proposed method, experiments are conducted based on the bearing datasets provided by Case
Western Reserve University (CWRU). The experimental results show that the bearing fault diagnosis method based on RP and the improved EfficientNetV2-S cannot only realise accurate identification of bearing faults but also accurately identify the degree of bearing fault with an accuracy of
99.85%.
Assessment of reinforced concrete corrosion degree based on the quantum particle swarm optimised-generative adversarial network
Authors: Lin Xumei , Yu Shijie , Wang Peng , Wang Shiyuan
Published: August 2024

Reinforced concrete corrosion inspection methods based on deep learning have been widely used in the engineering field to monitor the service status of reinforced concrete. However, in engineering practice, it is difficult to obtain a large amount of reinforced concrete corrosion data
of different types, which greatly hinders the improvement of the accuracy of neural network models in predicting corrosion conditions. The classic generative adversarial network (GAN) model gives poor model quality for datasets with small amounts of data and high concentration. This paper
proposes an improved generative adversarial network approach to optimise reinforced concrete corrosion data. Firstly, a quantum particle swarm optimisation (QPSO) algorithm is used to improve the generative adversarial network. Then, existing corrosion characteristic data is used to train
the improved generative adversarial network until the ideal equilibrium state is reached. Next, the feature data generated by the generator are fused with the original data and the fused data are input into several common machine learning models for training. Experimental results show that
compared with other conventional results obtained by directly inputting corrosion data into a neural network model for training, the improved method makes full use of multi-source signal data and achieves better classification performance.
Tarım Atıklarından Aktif Karbon Üretimi ve Atıksudan Boya Giderimi: Karakterizasyon, Kinetik ve Denge Çalışmaları
Authors: Yıldız Hakan
Published: August 2024

Tarım atıkları, sürdürülebilir ve çevre dostu atık yönetimi açısından büyük bir potansiyele sahiptir. Bu çalışmada, tarım atıklarından pamuk sapları kullanılarak aktif karbon adsorbenti üretilmiştir. Bu adsorbent ile atık sudan tehlikeli bir boyar madde olan malahit yeşilinin adsorpsiyon prosesi ile giderilmesi incelenmiştir. Adsorbentin BET, SEM ve FT-IR analizleri ile karakterizasyonu yapılmıştır. Adsorpsiyon etkinliğini belirlemek için boya konsantrasyonu ve pH gibi değişkenlerin optimizasyonu gerçekleştirilmiştir. Malahit yeşili adsorpsiyonunun doğası hakkında daha iyi bir anlayış elde etmek için kinetik ve denge çalışmaları yapılmıştır. Yapılan çalışmalar sonucunda, yalancı ikinci dereceden kinetik modelin adsorpsiyon sürecini en iyi şekilde temsil ettiği, Langmuir izoterminin ise denge özellikleri için en uygun model olduğu belirlenmiştir. Langmuir izoterm verilerine dayanarak, maksimum adsorpsiyon kapasitesi (qmax) 69.06 mg g⁻¹ olarak belirlenmiştir. Bu çalışma, atık pamuk saplarından üretilen adsorbanın çevre dostu, ekonomik ve etkili bir su arıtım malzemesi olarak potansiyelini ortaya koymaktadır.
Computational Analysis of Selected Phytochemicals for their PARP Inhibitory Potential in Cancer
Authors: Alam Mudassir , Abbas Kashif , Chaudhary Bharat , Asif Sana , Balti Ali Asgar
Published: August 2024

Poly (ADP-ribose) polymerase (PARP) inhibitors have emerged as promising agents in cancer prevention due to their ability to target the DNA repair machinery of cancerous cells. PARP enzymes repair single-strand DNA breaks through the base excision repair pathway. In cancer cells, particularly those with deficiencies in homologous recombination, PARP aids in DNA repair pathways and promotes cancer cell survival. PARP inhibitors suppress the enzyme function, thus inducing apoptosis in cancerous cells. Phytochemicals, bioactive compounds derived from plants, have gained increasing attention for their potential role in cancer prevention and treatment. We have investigated selected phytochemicals such as cinnamaldehyde, baicalein, curcumin, galangin, ellagic acid, resveratrol, pinocembrin, genistein, quercetin, and apigenin against PARP. The assessment of selected phytochemicals, including baicalein, galangin, ellagic acid, genistein, and apigenin, reveals promising attributes through various computational analyses. Specifically, these compounds exhibit favorable docking scores, indicating strong binding affinity to their target molecules. Molecular dynamic simulations for 10 nanoseconds were performed to validate the findings. Moreover, their potential as PARP inhibitors suggests a plausible role in inhibiting DNA repair mechanisms, an essential aspect of cancer therapy. These compounds were found to exert PARP inhibition through direct interference with enzymatic activity or modulation of PARP expression. This targeted investigation underscores the potential of these phytochemicals as PARP inhibitors, contributing to the advancement of precision cancer therapeutics.
Crocetin regulates cell cycle progression in N-nitroso-Nmethylurea(NMU)-induced breast cancer in rat: cyclin D1 suppression, p21Cip1 and p53 induction
Authors: Bathaie S. Zahra , Ashraf Mahboobeh , Azizian Mahshid , Khademian Narges , Abroun Saeid
Published: August 2024

Objectives: Crocetin, a saffron-derived carotenoid, inhibits tumor growth in some cancer types. However, its mechanism of action still needs to be clearly understood. Here, the Crocetin effect on the expression of some cell cycle regulators was investigated.
Methods: The N-nitroso-N-methylurea (NMU)-induced rat mammary carcinomas were induced in a group of 35-day-old female Wistar Albino rats. Then, the expression of several cell cycle regulators was studied using reverse transcription-polymerase chain reaction (RT-PCR) and Western blot. After the tumor appearance, these rats were treated with Crocetin through weekly, intraperitoneal injections of 100 mg/kg body weight for four weeks. A control group has received the vehicle only. In the end, rats were sacrificed, and tumors were divided into two parts. A part was for pathologic investigation, and a part was retained at -70 °C to determine desired parameters.
Results: Before Crocetin treatment, the tumor volumes were 13.27 ± 3.77 and 9.44 ± 4.39 cm3 , which was changed to 23.66 ± 8.82 and 4.71 ± 2.44 cm3 at the end of the experiment in the untreated and treated groups, respectively. The results showed that Crocetin markedly decreased the increased expression of cyclin D1 due to NMU administration. However, it further increased the expression of p53 and p21Cip1, with no significant effect on p27Kip1 expression. We previously showed Crocin-induced cell cycle arrest through a p53-dependent mechanism.
Conclusion: Crocetin induced the cell cycle arrest in NMU-induced breast cancer in rats through a p53-independent mechanism. It is the second mechanism additional to apoptosis induction in cancer cells.
Whole-genome sequencing of Salmonella phage vB_SenS_ TUMS_E15 for bio-control in the food chain
Authors: Torkashvand Narges , Kamyab Haniyeh , Shahverdi Ahmad Reza , Khoshayand Mohammad Reza , Karimi Tarshizi Mohammad Amir , Sepehrizadeh Zargham
Published: August 2024

The genome analysis of bacteriophages is crucial for their successful application in clinical and biocontrol settings. In this study, we isolated a new lytic phage, vB_SenS_TUMS-E15, from hospital sewage that was effective against Salmonella enteritidis, and analyzed its genomic features. The complete genome analysis revealed that E15 had circularly permuted double-stranded DNA of 43,048 base pairs (bp), with a G+C content of 49.7%. Sixty coding sequences (CDSs) were predicted in the genome, with 44 CDSs encoding known proteins in different modules, including packaging, structure, replication, metabolism, and lysis modules. No tRNA genes were found in the genome. Eight transcriptional promoter sequences and 37 rho-independent terminators were detected in the E15 genome. Phylogenetic analysis based on whole-genome sequences suggested that phage E15 should be classified as a member of the Jersyvirus genus in the subfamily Guernseyvirinae. Furthermore, no antibiotic-resistance genes, toxins, virulence factors, or lysogen-forming genes were observed in the genome. This suggests that E15 is a lytic phage, making it a promising candidate for clinical and biocontrol purposes.
Effects of Plasma Therapy on Laboratory Factors and Clinical Improvement of COVID-19 Patients
Authors: Ghezelbash Behrooz , Golabi Marjan , Tavakol Negah , Mesgari Azam , Shamsfar Reihaneh , Sami Ramin , Eskandari Nahid
Published: August 2024

Objectives: Over 50 million confirmed cases and 1.5 million fatalities worldwide have been linked to the COVID-19 pandemic. Researchers have used convalescent plasma (CP) from recovered patients, which includes neutralizing antibodies, to develop therapeutics for virus neutralization and prevention. This study assessed the effectiveness of CP using several clinical and laboratory variables.
Methods: The intervention group received two doses of CP on the day of hospitalization, while the control group received standard care. Clinical and analytical data were documented and evaluated before plasma therapy and on the third and fifth days after therapy. The results were measured in the patient’s blood using the ELISA method.
Results: The present study showed that the ICU hospitalization times for the control and CP groups were similar, with a slightly lower mortality rate in the CP group (6.2% vs. 8.2%, p > 0.05). There was no significant association between COVID-19 and clinical factors such as blood pressure, heart rate (HR), respiration rate (RR), and temperature. The blood serum urea, serum LDH, ALT, PTT, PLT, and IL-6 were significantly higher in the CP group than in the control group (p <0.05). Our results indicated that there was no difference in blood pH, PO2 , HCO3 , ESR, WBC counts, serum troponin, Na, AST, CRP, D-dimer, and PT between patients in the CP and control groups.
Conclusion: Overall, in certain instances, CP therapy may help individuals with COVID-19 recover. In general, additional research is required to determine the efficacy of plasma treatment in COVID-19 patient care.
Mid-term results of percutaneous transmitral commissurotomy (PTMC) in central iran
Authors: Andishmand Abbas , Montazer Ghaem Hossein , Fallahzadeh Somayeh , Andishmand Mojtaba , Haghaninejad Hasan , Dehghani-Tafti Faezeh , Namayandah Mahdiah , Nough Hossein
Published: August 2024

Objectives: Percutaneous Trans-Mitral Commissurotomy (PTMC) is an effective non-surgical treatment in patients with severe rheumatic mitral valve stenosis. This study aimed to evaluate the mid-term results of this procedure in central Iran.
Methods: This retrospective study was performed on 101 patients with severe mitral valve stenosis who underwent successful PTMC from March 2011 to September 2018 in Afshar Hospital in Yazd. At follow-up, all patients underwent clinical examination, two-dimensional and color Doppler echocardiography, and events were recorded. Data were analyzed using SPSS software version 19.
Results: The mean age of the patients was 44.79± 11.72 years, and 83.3% were female. The mean follow-up time was 38.98 23.33 months (6-94 months).25.8% had AF rhythm, and 12% had previous PTMC or OMVC or CMVC. After percutaneous Trans-Mitral Commissurotomy, 97% of patients were in NYHA functional class I, II and the mitral valve area (MVA) increased from 0.92 ± 0.18 to 1.66± 0.29 cm2 (p<0.0001). Pulmonary artery systolic pressure decreased from 46.96± 18.56 mmHg to 38.43±14.02 mmHg (p<0.0001). The Mean mitral valve gradient decreased from 12.37± 3.99 mmHg to 4.79± 2.38 mmHg (p<0.0001). Restenosis rate and severe mitral regurgitation resulting in mitral valve replacement (MVR) were 10.9% and 2%, respectively. Two patients died because of intracranial hemorrhage (ICH). During the follow-up event, free survival was 82.2%. Multivariable analysis revealed that the predictors of shorter event-free survival were AF rhythm (HR; 4.5, 95%CI;1.59-12.9, P=0.005) and post PTMC higher NYHA functional class (HR;2.2, CI;1-4.8,p=0.049).
Conclusions: Mid-term results of percutaneous transmitral commissurotomy (PTMC) in central Iran are the same as in other parts of the world. This procedure is an effective and low-risk treatment for severe mitral valve stenosis.
Unlocking the power of echocardiography: strategies in risk stratification of patients with PE using echocardiography
Authors: Shahabi Raberi Venus , Jafari Negar , Zadeh Reza Faramarz , Parizad Razieh , Kahourian Ozra
Published: August 2024

Objectives: Pulmonary embolism (PE) is challenging to diagnose due to nonspecific symptoms. While computed tomography pulmonary angiography (CTPA) is the gold standard, transthoracic echocardiography (TTE) is frequently used first. This study aimed to evaluate the accuracy of TTE findings in predicting the severity of CTPA-confirmed PE.
Methods: This retrospective study in 2023, analyzed 124 patients who underwent CTPA for suspected PE at Seyed Al Shohada Hospital of Urmia, Iran. The Pulmonary Embolism Severity Index (PESI), as a risk stratification tool for pulmonary embolism, was measured in the first hours of hospitalization. TTE was performed 48 hours following hospital admission, with an emphasis on Key TTE parameters, including McConnell’s sign, D-shape septum sign, right ventricular (RV) dimensions, left ventricular dimensions, pulmonary artery (PA) diameter, tricuspid regurgitation gradient (TRG), Tricuspid annular plane systolic excursion (TAPSE)  and PA acceleration time (PaACT). Sensitivity, specificity and predictive value were all calculated.
Results: Most patients were women (53.23%) over 60 (38.71%). Several TTE measures showed promise for predicting PE: RV dilation (sensitivity 84%, specificity 77%), PA diameter (84% and 28%), TRG (66% and 58%), and PA acceleration time (92% and 62%). However, McConnell’s sign had low accuracy (area under ROC curve 0.62). Tricuspid annular plane systolic excursion (TAPSE) and PA acceleration time showed the best predictive performance (AUC 0.95-0.92) and can be used as screening tools for life-threatening massive PE.PESI index test, when compared to the gold standard CT scan (which shows lung involvement), does not provide additional valuable information and accurate predictions about the severity of PE.
Conclusions: TAPSE and PaACT showed excellent predictive ability to CTPA-detected PE. RV dilation and PA diameter also showed good predictive capability. Findings support using some TTE indices to screen for PE severity and risk assessment before CTPA when access is limited.
The role of serum uric acid in predicting left ventricular function and outcomes in patients with STEMI following PCI
Authors: Haghaninejad Hasan , Banifatemeh Seyed Ali , Mohammadi Hamidreza , Razavi Ratki Seyed Kazem , Moghadam Reza Nafisi , Namiranian Nasim , Taheri Asl Ghazal
Published: August 2024

Objectives: Percutaneous coronary intervention (PCI) is the preferred treatment for ST-elevation myocardial infarction (STEMI); however, reduced left ventricular ejection fraction (LVEF) remains a critical issue post-PCI. Serum uric acid (SUA) has emerged as a biomarker linked to cardiovascular events and may be associated with LVEF. This study aims to investigate the relationship between SUA levels and LVEF in STEMI patients treated with primary PCI and identify potential biomarkers for predicting patient outcomes.
Methods: This prospective study was conducted at Afshar Hospital, Shahid Sadoughi University of Medical Sciences of Yazd, from September 2019 to March 2021. Participants included 254 consecutive ST-elevation myocardial infarction (STEMI) patients undergoing primary PCI. Exclusion criteria were contraindications for angiography, history of myocardial infarction, PCI, CABG, NSTEMI, thrombolytic treatment, kidney diseases, gout, or alcoholism. Demographic data, clinical history, SUA levels, and echocardiographic parameters were collected. Statistical analysis was performed using SPSS version 20.0, with significance at p<0.05.
Results: 81.49% of patients were male, with a mean age of 57.7±11.47 years. Hypertension was the most prevalent condition (42.9%). SUA levels did not significantly differ between patients with LVEF below and above 40% (p=0.39). However, smoking was significantly associated with reduced LVEF (p<0.001). A weak negative correlation between SUA and LVEF was observed in males (p=0.012) but not in females (p=0.097). Overall, a weak negative correlation between SUA and LVEF was statistically significant (p=0.05).
Conclusions: Our findings revealed a weak but statistically significant overall negative correlation between SUA and EF. Further research with larger, more diverse populations is necessary to elucidate the relationship between SUA and cardiac function in STEMI patients.
Impact of preexisting hypertension and antihypertensive medication on prognosis of COVID-19 patients
Authors: Gholinataj Jelodar Mohsen , Mirzaei Samaneh , Hajimaghsoudi Majid
Published: August 2024

Objectives: Coronavirus disease-2019(COVID-19) patients with comorbidities experience severe disease. Hypertension (HTN) is one of the most common comorbidities seen in these patients. The published reports are conflicting regarding the role of HTN and antihypertensive medication on the in-hospital prognosis of COVID-19 patients. This study investigated the effect of HTN on the prognosis of hospitalized COVID-19 individuals and sought to identify the risk factors for worse clinical outcomes in this population.
Methods: This descriptive-analytical observational study was conducted on COVID-19 patients hospitalized in two teaching hospitals (Shahid Rahnemoon and Shahid Sadoughi) in Yazd, Iran from February 20, 2022, to April 20, 2022. All hospitalized patients with positive polymerase chain reaction (PCR) tests for COVID-19 were included in the study. The demographic, laboratory, imaging, pharmaceutical and clinical data were extracted and analyzed by SPSS v-26.
Results: Out of 615 participants, 243 had HTN. Hypertensive patients had significantly more need for Intensive Care Unit (ICU) admission (P=0.001) and endotracheal intubation (P<0.001) and experienced higher mortality (P<0.001). The length of hospital and ICU stay and duration of endotracheal intubation were not significantly different. No antihypertensive medication was found to impact the patient's prognosis significantly. In hypertensive individuals, the multivariate regression analysis revealed the vaccination status (OR=0.27; CI 95%: 0.10-0.69), a score of Computed tomography (CT) scan involvement (OR=7.49; CI 95%: 3.50-16.01), and neutrophil-to-lymphocyte ratio (NLR) (OR=1.05; CI 95%: 1.00-1.11) as the predictors of need to ICU admission.
Conclusions: Hypertensive COVID-19 patients experience higher mortality and require more ICU admission and endotracheal intubation. None of the antihypertensive drugs had a significant effect on prognosis. The vaccination status, NLR, and the degree of lung involvement in chest imaging predicted the need for ICU admission in this subgroup of patients.
Isn’t the killing of more than 13 thousand children in Gaza and the destruction of 35 hospitals, a case report?
Authors: Akhondzadeh Shahin
Published: August 2024

The Article Abstract is not available.
A case report of lymphohistiocytic hemophagocytosis syndrome with Syntaxin11(STX11) positive gene and co-infection with Leishmania
Authors: Jafari Mohsen , Ghodsi Maryam , Noory Maryam , Torshizi Mahdieh Mousavi , Kaji Yazdi Mohammad
Published: August 2024

Background and Purpose: Hemophagocytic lymphohistiocytic syndrome is a rare, significant, and life-threatening disease. We are reporting this case with the hope that it may contribute to saving some patients if treated appropriately.
case: A 4-year-old boy presented with fever and pancytopenia. He was treated based on the symptoms that matched the criteria of (HLH). Furthermore, the bone marrow biopsy report revealed the presence of Leishman’s bodies.
Conclusion: Hemophagocytic lymphohistiocytic syndrome is a rare, important and life-threatening disease that we are reporting this case due to the hope of saving some patients if treated. A 4-year-old boy with fever and pancytopenia, who was treated according to the symptoms matching the criteria of HLH, as well as the bone marrow biopsy report showing Leishman’s bodies. HLH is a life-threatening disease based on cumulative increase and unrestricted excessive activity of T lymphocytes, cytokines and macrophages, which occurs in two primary and secondary forms, which requires the rejection of all risk factors, symptoms similar to the disease, including infections, lymphoproliferative and autoimmune diseases and other causes, and after ruling out other causes, the patient should be treated quickly with the treatment protocol of this disease, which is reported.due to the rarity of this disease and the urgent need for timely diagnosis and treatment; we are trying to report this patient
Accidental Journeys: Intrauterine Contraceptive Device Migration to the Sigmoid Colon and Right Ovary – A Report of Two Cases
Authors: Al-wageeh Saleh , Ahmed Faisal , Alyhari Qasem , Altam Abdulfattah
Published: August 2024

Ectopic migration of intrauterine contraceptive devices (IUCDs) to neighboring organs is infrequent, but can lead to severe consequences. This article presents two cases of IUCD migration resulting in serious outcomes, including sigmoid colon penetration in the first case (a 25-year-old) and right ovary penetration and contraceptive failure leading to pregnancy in the second case (a 19-yearold). The IUCD was inserted 6 months ago and 2 years ago in the first and second cases, respectively. Both cases underwent surgical exploration and IUCD removal. Fortunately, both patients experienced uneventful recoveries without any complications. In conclusion, although uncommon, IUCD ectopic migration may result in contraceptive failure and, in some cases, organ perforation. Thorough evaluation during care visits is necessary for proper IUCD placement, and radiological assessment should be performed in cases of a ‘missed IUCD,’ even if the patient is asymptomatic. Timely removal of an ectopic IUCD is strongly advised to minimize potential risks.
Airbag Deployment and Tinnitus Emergence Following Car crash, a Case Report and a Brief Literature Review
Authors: Azizi Mohammad Hossein , Aghanejad Frough
Published: August 2024

Automatic airbag deployment during car accidents undoubtedly plays a vital role in preventing injuries. However, it may occasionally lead to aural damage, including noise-induced hearing loss, tympanic membrane perforation, and tinnitus. Here, we present a case of left curtain airbag deployment immediately following a low-speed car accident, which resulted in the driver experiencing tinnitus. In addition to the case presentation, we have included a brief literature review on potential otologic and nonotologic injuries caused by airbags
Epidemiology of Human Monkeypox about the 2022 Outbreak: A Narrative Review
Authors: Fakhri-Demeshghieh Aliasghar , Akbarein Hesameddin , Almasi Parsa
Published: August 2024

Abstract:  Human Monkeypox is a zoonotic disease caused by 2 distinct clades of human monkeypox virus (MPXV). MPXV infections can cause several clinical symptoms including fever, skin rash, back pain, and lymphadenopathy in humans. Even though MPXV infections are generally self-limiting, death is possible and fatality due to MPXV infections in humans is 3-6 percent. While the disease is endemic to Africa, its potential to cause outbreaks in other continents has been observed. The natural reservoir of MPXV in Africa and the full host range of the virus are not known, but rodents are suggested to be the reservoirs. The transmission of MPXV occurs via close contact and the prevention strategies include avoiding close contact and post-exposure prophylactic vaccination of people at risk with smallpox vaccines. In this study, the most recent information about the epidemiology of MPXV about the latest research on the 2022 outbreak of MPXV has been reviewed.
Investigation of Peroxidase-Like Activity of Flower-Shaped Nanobiocatalyst from Viburnum Opulus L. Extract on the Polymerization Reactions
Authors: Kalaycı Berkant , Kaplan Naime , Mirioğlu Müge , Dadı Şeyma , Öçsoy İsmail , Göktürk Ersen
Published: August 2024

Here, we report the effects of peroxidase-mimicking activity of flower shaped hybrid nanobiocatalyst obtained from Viburnum-Opulus L. (Gilaburu) extract and Cu2+ ions on the polymerization of phenol and its derivatives (guaiacol and salicylic acid). The obtained nanoflowers exhibited quite high catalytic activity upon the polymerization of phenol and guaiacol. The yields and the number average molecular weights of the obtained polymers were significantly high. Due to solubility issue of salicylic acid in aqueous media, polymerization of salicylic acid resulted in very low yields. Free-horseradish peroxidase (HRP) enzyme is known to be losing its catalytic activity at 60 °C and above temperatures. However, the synthesized nanoflowers exhibited quite high catalytic activity even at 60 °C and above reaction temperatures. This provides notable benefits for reactions needed at high temperatures, and it is very important to use these kinds of nanobiocatalysts for both scientific studies and industrial applications.
Unilateral Double Superior Cerebellar Artery Variation: A Cadaveric Case Report
Authors: Sönmez Sefa , Özgen Merve Nur , Kasap Abdulkerim , Nahir Mert
Published: August 2024

The superior cerebellar artery (SCA) is a vessel anterior to the brainstem, usually originating from the basilar artery (BA). In this case, a different course of left SCA in a 74-year-old male cadaver was reported. The origin of the SCA was found to be a unilateral double root at the left side on the anterior surface of the pons. The distances of the starting points of roots to the bifurcation of BA were 31.09 mm on the right side, on the left side the rostral root was 33.84 mm and the caudal root was 30.95 mm. The diameter of the right SCA was 2.37 mm, the left rostral root was 2.05 mm and the caudal root was 1.24 mm. Knowing the course of SCA, and especially morphological variations, will be helpful for the clinical branches in preventing complications during surgical operations, evaluating angiographic examinations, and diagnosing and treating neurovascular diseases.
The Effect of Prolotherapy and Dry Needling on Pain and Foot Functions in Hallux Valgus
Authors: Sağlam Sönmez , Aydın Mustafa , Yüzügüldü Uğur , Erşen Ömer , Uludağ Veysel
Published: August 2024

Aim: Hallux valgus is a common foot deformity that causes significant pain and functional impairment. This study aimed to compare the effectiveness of prolotherapy and dry needling in treating mild to moderate hallux valgus pain.
Material and Methods: Patients with hallux valgus deformity experiencing refractory pain after orthotic and analgesic treatment, and treated with prolotherapy (52 patients, 68 feet) or dry needling (49 patients, 57 feet) methods were included in the study. Each group received three treatment sessions at 3-week intervals. Clinical assessments were performed using the visual analog scale (VAS) and American Orthopedic Foot and Ankle Society (AOFAS) scores at baseline, in the third month, and twelfth month.
Results: Both groups showed significant improvement in VAS and AOFAS scores after treatment (p
Peran Spesialisasi Industri Auditor dalam Memoderasi Pengaruh Audit Tenure dan Ukuran KAP terhadap Audit Report Lag
Authors: Misnawati  , Nindito Marsellisa , Khairunnisa Hera
Published: August 2024

This study aims to determine the role of auditor industry specialization in directing the impact of audit tenure and size of Public Accounting Firm on audit report lag. Sampling was carried out with the aim of purposive sampling. Panel data regression analysis was used to test the hypothesis, and the sample size included 30 energy sector companies listed on the Indonesia Stock Exchange between 2021 and 2023 with outlier data. Based on the findings of this study, audit report lag is significantly affected by auditor industry specialization and tenure, but not by the size of the Public Accounting Firm. While auditor industry specialization does not moderate the effect of Public Accounting Firm size on audit report lag, it does moderate the effect of audit tenure on audit report lag.
"Inspired to be a teacher seriously": An autoethnography of student engagement in a Vietnamese TESOL training programme
Authors: Huynh Huy-Hoang , Pretorius Lynette
Published: August 2024

TESOL (Teaching English to Speakers of Other Languages) training programmes in Vietnam often emphasise the significant alignment of academic knowledge with practical classroom methods. However, an intricate yet underexplored topic is understanding the dynamic engagement of student teachers in those programmes to investigate the complexities of such alignment. Therefore, this research examines factors influencing student teachers’ in-class engagement following a 120-hour TESOL training programme at an institution in Vietnam.      This autoethnographic study analysed a TESOL teacher trainer’s reflections on student teachers’ engagement in the programme, using artefacts in the form of anonymous and open-ended short-text feedback from 30 students across approximately eight months. The reflection and feedback responses were analysed thematically, anchored in a framework emphasising the three facets of in-class engagement, i.e., cognitive, emotional, and behavioural dimensions. Through the analysis, three themes were constructed: (1) theoretical-practical synthesis: how TESOL-related concepts are blended with concrete teaching examples; (2) pedagogical climate: the teacher educator’s critical role in creating a receptive and engaging learning environment; and (3) professional pathway clarity: the student teachers’ understanding of their future roles and trajectories in the TESOL arena. The research’s findings provide TESOL educators with crucial insights into student teachers’ engagement with teaching methods that synthesise both theoretical and practical components. Moreover, the research enriches the academic discourse, underscoring the potential of using the cognitive, emotional, and behavioural engagement triad as a diagnostic tool to understand students’ learning experiences in TESOL training programmes.
An updated method on the injectivity of integral operators related to Riemann Hypothesis
Authors: Adam Dumitru
Published: August 2024

With this paper, a reformulation and improvement of the previous version v3 of [2] and a continuation of [1], we provided a solution for the Alcantara-Bode equivalent formulation ([3]) of the 165 years old Riemann Hypothesis - one of the Clay Inst. \textit{Millennium Problems}.
We consider it to be a solution in the areas of numerical analysis, applied math rather than in the field of number theory as expected but, for someone who needs to have an answer for RH they could find it here.
The Alcantara-Bode equivalence (1993) of the Riemann Hypothesis (RH, 1859) consists in the injectivity of a certain Hilbert-Schmidt integral operator, result obtained from Beurling equivalent formulation of RH (1955).
Both outstanding equivalences reduced RH to a problem dealing with the injectivity of a specific linear bounded operator on a separable Hilbert space.
The scenario behind Theorem 1, a generic result in the area of functional analysis and its associated methods is briefly described below. Given T a linear operator bounded on a separable Hilbert space H without zeros in a dense family of finite dimensional subspaces, its zeros, if any, should be in the difference set between the Hilbert space and the dense set of the union of the subspaces. The methods, the Corollary and the Injectivity Criteria exploit the strict positivity of the operator on the family subspaces as well as the density of the family in H, in order to obtain the sufficient conditions imposed to our operator for its injectivity.

With both methods we proved the Alcantara-Bode equivalence, meaning: the Riemann Hypothesis holds.