bluuebunny/crossref_metadata_2025 huggingface dataset:
Modular-Based Multifunctional Product Design Made from Furniture Waste Toward the Circular Economy: Case in Indonesia
Authors: Sari Diana Puspita , Hartini Sri , Azzahra Faradhina , Arsiwi Pramudi , Prayoga Riswanda G.
Published: September 2024

The furniture industry is one of the industrial sectors that has a potential market in Indonesia. This industry requires a lot of wood raw materials but is faced with a wood legality verification system that limits raw materials. Industrial players still need to start using waste as raw materials, which will reduce the use of primary raw materials. The circular economy concept can be applied to waste treatment. This study aims to design a pump-gallon product made from waste, considering the relatively high level of gallon container consumption. With this design, it is hoped to utilize waste into economically valuable products while reducing the environmental impact it causes. The product design process uses an integrated QFD-TRIZ method combined with circular economy principles. QFD functions to determine consumer desires and make technical responses, while TRIZ resolves contradictions in technical responses. The circular economy attribute is used as a reference in making gallon pump products from wood waste. After the design process is complete, it is followed by an economic feasibility analysis using the cost-benefit ratio. The result of this research is the design of multifunctional and modular products for gallon pumps. The gallon storage is designed to store not only gallons but also a small table for placing dirty glass and a drawer at the bottom that can be used to keep the glass or other items. There is a detachable system between the upper and lower components, making it easier to repair and use. At the bottom, they mounted castor wheels to facilitate product movement. Designing products made from waste will increase the income of furniture SMEs. In addition, it is expected that this will overcome waste management problems and shortages of raw materials experienced by furniture SMEs. Future research can utilize powder and smaller pieces of wood.
Managing Risk and Uncertainty in Machine Replacement Decisions Using Real Options Analysis and Monte Carlo Simulation
Authors: Momani Amer , Khrais Samir , Almahmood Ro’a
Published: September 2024

The present research discusses the application of risk management tools and Real Option Analysis (ROA) to assess and quantify managerial flexibility in machine replacement decisions under uncertain conditions. Different management configurations are used for the real options approach: options to execute, options to delay, and options to cancel. This reflects the uncertainty inherent to each stage of planning. Uncertainties such as future demand and life-cycle costs are implemented in the model as probability distributions. Monte Carlo simulation is employed to deal with such uncertainties and to facilitate experimental trials. The net present value is used as a decision criterion to determine the best replacement option under different replacement and real option scenarios. Herein, a case study to evaluate different replacement alternatives was conducted for the garment industry. Results of the stochastic net present value, mean-standard-deviation scatter plot, and stochastic dominance showed that the best option was to rent and then buy a new machine of reduced size but greater technological advancement. Finally, tornado diagrams and perfect control methods were used to analyze uncertain factors in order to improve the model and further minimize uncertainty effects.
Generating Models for Numerical Strength Tests of 3D Printed Elements
Authors: Bołoz Łukasz
Published: September 2024

Additive manufacturing, or 3D printing, has become very common in professional applications in many industries. The 3D printing technology is especially suitable for making prototypes, demonstrators and small-batch production. The stiffness and strength of 3D prints depend on many factors, including among others infills, which are specific to this technology, as well as the orientation of the object during 3D printing. Where the stiffness or strength of an element is crucial, the only way is to empirically assess its properties. The advantage of 3D printing, i.e. incomplete infill of the interior of an object with the use of different types of infills (patterns) and different amounts of material, means that its mechanical properties differ from those of a solid element. The application of numerical tests, i.e. the finite element method (FEM), requires the creation of a 3D model while taking this infill into account. The modelling of elements for performing numerical strength calculations is time-consuming and labour-intensive. The article presents a proprietary original analytical method for generating various types of infills with varying infill density. The method was developed for typical infills (Grid, Triangular, Honeycomb). It was next implemented in the CAD environment using the iLogic tool of Autodesk Inventor. As a result, a tool for creating 3D models of objects consistent with those obtained from 3D printing was obtained. The method and tool were verified. Next, the influence of selected parameters of the 3D print on its mechanical properties was presented on three real objects. The results of numerical analyses revealed measurable benefits of such tests. The research conclusions also constitute recommendations for selecting the type and infill density of an object and its orientation in the printer with regard to the strength and stiffness obtained.
Clustering Based Heuristics for Aligning Master Production Schedule and Delivery Schedule
Authors: Astanti Ririn Diar , Ai The Jin
Published: September 2024

Making a Master Production Schedule (MPS) is a very important activity for a manufacturing industry. This is due to the fact that MPS serves as an input for material and production planning. Between the years 2020 and 2022, there were significant fluctuations observed in container freight rates. As response, a lot of manufacturing industry focus on optimizing their container delivery schedule. Hence, there is a need for aligning the master production schedule with the delivery schedule. This paper presents the development of a novel heuristic approach to address problems with the creation of MPS. Specifically, the focus is on the situation where container delivery schedules are prearranged and serve as a main input for creating the MPS. There are two objective functions that are going to be reached: 1) minimize the total number of product variations or Stock Keeping Units (SKU) per month; and 2) minimize the number of SKU per container. The proposed heuristic approach uses the similarity concept to group objects in a clustering technique. It is then implemented in a real-world case of a furniture manufacturing company. Further results were obtained and then compared to the heuristic technology that had previously been used by business entities. The results show that the number of product variations (SKU) that must be performed per month is 10% lower than that of the existing heuristic. In addition, the ratio of SKU variations per container is 9% lower than that of the existing heuristic. The time required to complete the task of creating MPS is less than one minute, as opposed to the one working day required by the company’s existing heuristic.
Study of the Migration Attractiveness of the Countries of the European Continent: Analysis of the Factors of its Formation
Authors: Mosora Larysa , Lopushynskyi Ivan , Midor Katarzyna , Bembenek Michał
Published: September 2024

The article presents the author’s approach to the classification of types of attractiveness that may be characteristic of certain European countries. The migration attractiveness of countries is highlighted and a list of factors that can affect it is given. Factors were ranked according to the level of their impact on population migration, among which the following were highlighted: the economic development of countries, production processes, the use of more modern technologies, ensuring one’s financial well-being, and the culture of the production environment. The dynamics of the number of immigrants who moved to the studied European countries since 2020 are given. The main programs under which European countries accept migrants for permanent residence are considered the issues of providing housing, employment in the industrial infrastructure, and increasing the level of professional competence in various fields. To conduct a comparative assessment of the attractiveness of European countries for potential migrants, a set of available statistical indicators was selected, which fully reflects the main parameters of the countries’ attractiveness. Individual results obtained in the process of assessing the migratory attractiveness of the countries of the European Continent are presented, and proposals for its improvement are presented. It is proved that increasing migration attractiveness is possible by improving the social and economic attractiveness of countries. To do this, countries should create conditions for the development of various industries, create additional jobs, provide high wages, social services, protection, etc. to attract as many highly skilled labor resources from other countries as possible. As a result, the growth in the number of professional labor migrants in countries will contribute to the development of those industries that are common in the respective countries.
Temperature response as a contralateral effect of physiotherapy
Authors: Piętka Tomasz , Knapik Katarzyna , Sieroń Karolina , Kasprzyk-Kucewicz Teresa
Published: September 2024

Introduction: In the presented research, we characterized the contralateral effect after applying capacitive and resistive transfer of energy (TECAR) in the treatment of active myofascial trigger point (MTrP). In order to assess the contralateral effect, we used the infrared thermovision method. We hypothesize that by means of thermal imaging studies, we will be able to present and confirm the contralateral effect which can be important in establishing the MTrP treatment protocol with the use of TECAR.

Material and methods: In the study, thermographic imaging was performed on a group of 6 volunteers with an age range [25-45] years (mean age: 32.3 years ± 9.83 years) who were randomly selected for the study from among people practicing recreational sports and showing the clinical presence of active MTrP in the upper trapezius muscle (UT).

Results: On both sides, the reference area (side untreated) and the target area (side treated), there was an increase in the percentage changes of isotherms. These results indicate the presence of a contralateral effect. The use of TECAR therapy ipsilaterally in the treatment of MTrP in UT results in an increase of temperature on the symmetrical body part and it may be connected with the presence of vascular contralateral effect on the untreated side.

Conclusions: These changes were investigated by IR which, as our research shows, can be an effective form of assessing the therapeutic effects of TECAR in MTrP treatment.
Purification of Crude Glycerol Derived from Hydrogenated Cottonseed and Its Use in Confectionary Products
Authors: Ruzibayev Akbarali , Abdurakhimov Ahror , Calvo-Gomez Octavio , Akhmedova Shahlo , Kurambayev Sherzod
Published: September 2024

Glycerol is a versatile substance used in food, beverages, cosmetics, and technical applications. It can be derived from fats and oils through 4 different reactions, including: transesterification, directed hydrogenation, hydrolysis, and saponification. Glycerol derived from fat hydrolysis yields superior quality and quantity when compared to saponification. The resulting glycerol water is purified and concentrated through evaporation to yield crude glycerol with a concentration of 86-88%. Two distinct methods are recognized for further improving quality of glycerol: distillation, and the purification of glycerol water through the ion exchange process followed by evaporation. The goal of this research was to improve the purification process of glycerol, for obtaining premium-quality glycerol without the need for distillation, through the utilization of cations. Several combinations of activated carbon and clay were tested, and it was determined that a combination of 70:30 yielded the optimal results, considering the amount of glycerol and ash content. Technological parameters such as reaction durations, pH, and process temperatures were investigated, and it was discovered that the appropriate combination was a process duration of more than 40 minutes, a pH value of 2, and a temperature of 70°C. Besides, it was also determined that the concentration and quality of glycerol derived from cottonseed oil can be enhanced through distillation or purification with cationite. Moreover, different concentrations of glycerol on the elaboration of gingerbread were tested, and the conclusion is that adding 5% of the resulting glycerol to the gingerbread recipe could ensure better preservation of its quality during its shelf life.
Study of Amino Acid Profile and Solubility of Pea Protein Isolate for the Production of Beverages for Psychiatric Patients
Authors: Plocina Lasma , Beitane Ilze
Published: September 2024

Excessive intake of saturated fatty acids and physiologically imbalanced amino acids worsens the patient’s psychotic condition, creating the risk of developing psychosis and other comorbidities. Therefore, to ensure the optimal amount of amino acids and improve the psychotic state, pea protein isolate is an alternative to nutritional supplementation. The aim of the study was to analyse the amino acid profile of pea protein isolates and their solubility to evaluate their potential for the development of beverages for patients with psychiatric disorders. In the study, the amino acid profile analysis of organic and conventional pea protein isolates was performed using high performance liquid chromatography mass spectrometry. To evaluate solubility, pea protein isolates were treated in an ultrasonic bath and at different pH concentrations. The results showed that organic pea protein isolate showed a higher composition of essential amino acids (41.27%) and semi-essential amino acids (8.37%) than conventional pea protein isolate. Organic pea protein isolate was able to provide a more appropriate amino acid composition to meet the amino acid needs of patients with psychiatric disorders. Organic and conventional pea protein isolates had higher solubility in the ultrasonic bath of 20 min and in the alkaline environment. The solubility between the two pea protein isolates was not significantly different, but the ultrasonic bath treatment and different pH concentrations were significant, which gave insight and further application in beverage production.
Gut Microbiome Differences Regarding Lifestyle and the History of COVID-19 Disease in Ulcerative Colitis Patients
Authors: Straume Zane , Krūmiņa Nikola , Elbere Ilze , Rozenberga Maija , Blomniece Laura , Erts Renārs , Rudzīte Dace , Kloviņš Jānis , Krūmiņa Angelika
Published: September 2024

The microbiome’s role in ulcerative colitis pathogenesis is established. The influence of lifestyle on gut microbiome composition remains unclear, and interplay with COVID-19 disease warrants investigation. In a cross-sectional study conducted from June to December 2021, 49 outpatients from Rīga East Clinical University Hospital were included. Patients were categorised based on COVID-19 disease status (positive vs. negative) within the preceding six months. Lifestyle factors (smoking, alcohol consumption, physical activity, stress levels, and dietary patterns) were assessed and evaluated. Taxonomic classification of gut microbiome metagenome data was performed using MetaPhlAn v.2.6.0, with subsequent analysis conducted using SPSS 20.0. Thirty-one (63%) were male, and 18 (37%) were female patients. Fourteen patients (28.6%) tested positive for COVID-19. Gut microbiome composition differences were not observed between COVID-19 disease groups. Twenty-four (49%) patients engaged in sports activities and 30 (61.2%) patients reported a history of smoking. No significant microbiome differences were observed in groups regarding physical activity or smoking. Thirty-five (71.4%) were alcohol users, for whom Firmicutes abundance was significantly higher compared to non-users, p = 0.041. Patients reporting lower stress levels (18, 36.7%) exhibited higher Actinobacteria abundance compared to those with higher stress levels (31, 63.3%), p = 0.03. COVID-19 disease status did not affect gut microbiome composition, alcohol consumption and stress levels demonstrated significant associations.
Patient with Newly Diagnosed HIV Infection in Aids Stage Who Developed Oesophageal Candidiasis and Miliary Tuberculosis: A Case Report
Authors: Jevsjutina Žanna , Zeltiņa Indra , Šurpicka Anda
Published: September 2024

This clinical case is about a 50-year old woman, a refugee from Ukraine, without known epidemiological risk factors, with newly diagnosed human immunodeficiency virus-1 (HIV-1) infection in acquired immune deficiency syndrome (AIDS) stage. Qesophageal candidiasis as an indicator disease of HIV in this case was the first diagnosis that promoted further investigation, revealing both primary HIV infection and sequentially other opportunistic infections — cytomegalovirus, Epstein Barr virus, and miliary tuberculosis. Oesophageal candidiasis was visualised by the oesophagogastroduodenoscopy method, which was initially performed due to detected anaemia to rule out bleeding from the gastrointestinal tract. Deep immunosuppression was provided to this patient and this led to the development of miliary tuberculosis, worsening the prognosis. The patient was prescribed treatment for several opportunistic infections, also anti tuberculosis treatment, as well as combined antiretroviral treatment, which stabilised the situation. In this case our patient developed odynophagia and dysphagia, common complications of oesophageal candidiasis, so she had to receive nutrition through a nasogastric tube.
Acute Liver and Kidney Failure as the Presentation of Leptospirosis: Case Report of a Rare Differential Diagnosis in Case of Jaundice
Authors: Makarova Angelina , Ekšteina Ilze , Sperga Māris , Elsberga Evija , Klimovičs Toms , Zeltiņa Indra
Published: September 2024

Leptospirosis is a widespread and potentially fatal zoonosis that is endemic in many tropical regions. It is the most common zoonotic infection in the world, but a rare disease in Latvia. The clinical manifestations and the severity of leptospirosis are highly variable. This case report describes a 64-year-old male without comorbidities, who was admitted to Rīga East University Hospital in the Gastroenterology Department due to expressed jaundice, weakness, and acute kidney injury. The initial inpatient clinical diagnosis was initially acute alcoholic hepatitis, as the patient had consumed alcohol a month before hospitalisation. The clinical and laboratory picture of the patient was dominated by significant hyperbilirubinemia, a relatively small increase in liver transaminases, preserved synthetic liver function, acute kidney failure in the polyuria phase, and severe thrombocytopenia. During hospitalisation, the study of anamnesis and the results of laboratory tests gave grounds for suspecting the diagnosis of leptospirosis, which was subsequently serologically confirmed. Routine laboratory tests are not specific for diagnosing leptospirosis. Diagnosis is made on the basis of the doctor’s request and clinical examination, as well as on the basis of blood and urine culture and serological tests. Early initiation of antibiotic therapy plays an important role in controlling infection and reducing mortality.
2D speckle tracking in echocardiography in hypertrophic cardiomyopathy and its relation to hypertrophy and late gadolinium enhancement extent
Authors: Krid Marouan , Jebberi Zeynab , Boudiche Selim , Ezzaouia Khaled , Ouali Sana , Aouji Cyrine , Mghaieth Fathia , Mizouni Habiba , Halima Manel Ben , Mourali Mohamed Sami
Published: September 2024

Introduction

The relationship between cardiac deformation by 2D speckle tracking, hypertrophy, and the extent of late gadolinium enhancement (LGE) in patients with hypertrophic cardiomyopathy remains uncertain. Our study aims to compare left ventricular global longitudinal strain (GLS) with the extent of LGE and to determine a relationship between GLS and hypertrophy.

Methods

We conducted a descriptive cross-sectional single-center study that included patients aged 16 or above. Participants underwent echocardiography and cardiac MRI. GLS was assessed through 2D speckle tracking. LV mass index and LGE extent (LGE% = LGE volume/ LV mass) were calculated from MRI. Patients were divided into three groups based on LGE extent for analysis (LGE extent = 0; < 15%; ≥ 15%),

Results

Forty-two patients were included, 15 having a LGE extent ≥ 15%, 16 having an extent < 15%, and 11 having no LGE. Patients with LGE ≥ 15% had significantly lower global longitudinal strain, higher LV mass index, and higher maximal wall thickness compared to those without LGE (p= 0.016, p=0.025, and p=
0.003, respectively). A GLS cutoff value of -13.95 % predicted a LGE extent ≥15% with a specificity of 63% and sensitivity of 66.7%. Area Under the Curve (AUC) of 0.691 (95% CI 0.515 - 0.868) p=0.042. Patients with higher LV mass index had lower GLS (p<0.0001).

Conclusions

The study suggests a correlation between GLS, LGE extent, and hypertrophy in HCM patients. These findings indicate that GLS could be a promising tool for sudden death risk stratification as the LGE extent.
The Role of Radiosurgery in the Treatment of Brain Metastases
Authors: Dantas Bruno Rafael Chaves , Carrizo Juliana Fernandes Areal , Pessoa Fabrício Silva , Mendonça Gilberto José Góes de , Balestrero Julia Gomes Pimentel , Barreiros Lucas Cezar , Araújo Beatriz da Silva , Lembo Neto Giovanni , Barbosa Geovanna Karen da Silva , Garcês Marcella Aparecida Carvalho , Theodorovitz Armando Tomaz , Filho Maurício Caetano Lourenço , Ferreira Yasmin Lopes , Maldonado João Victor de Oliveira , Brito Rodrigo Gomes
Published: September 2024

Objective: This article explores the role of radiosurgery in the treatment of brain metastases, evaluating its effectiveness in improving clinical outcomes and patient quality of life. Technical challenges and the need for advanced technologies and integrated policies to overcome implementation barriers are discussed. Interdisciplinary collaboration is highlighted as essential for optimizing therapeutic outcomes.
 
Theoretical Framework: The effective application of radiosurgery in the treatment of brain metastases is crucial, given the increasing incidence of these lesions and their association with severe complications such as neurological deficits, cerebral edema, and deterioration in quality of life.
 
Method: A narrative literature review was conducted using the major scientific databases to collect articles on the use of radiosurgery in the treatment of brain metastases. Key studies were evaluated to measure the effectiveness of this approach in treatment precision and the preservation of healthy brain tissue.
 
Results and Discussion: The review revealed that radiosurgery in the treatment of brain metastases is effective in reducing neurological complications, improving patient survival and quality of life. Implementation barriers include limited access to advanced technologies and the management of patients with multiple brain lesions. To optimize treatment and outcomes, it is essential to improve access to specialized care, continuously train healthcare professionals, and develop integrated policies and innovative technologies, aiming for a more effective approach and the reduction of treatment-associated complications.
Mapping the Discourse: Scientometric Analysis of Affordable Housing Research Trends
Authors: Sohaimi Nor Suzylah , Hanafiah Nur Aili Hanim , Manaf Azhani Abd , Tülay Zıvalı
Published: September 2024

Affordable housing is not merely about cost but encompasses quality, safety, and accessibility. The shortage of affordable housing perpetuates cycles of poverty, negatively impacting well-being. Utilizing scientometric techniques —co-authorship analysis, citation network analysis, and keyword co-occurrence analysis— on Scopus data from 1999 to 2024, and employing the VOSviewer tool, the aim of this study is to provide a comprehensive understanding of housing affordability by integrating both monetary and non-monetary factors and identifies 1) the co-authorship, co-occurrence, and countries’ collaboration, and 2) the most cited article in the field.  The results reveal key contributors in affordable housing research, highlight influential works, and map publishing trends. The outcomes show that nine different groups exist and actively collaborate worldwide. Waddell’s work, with 873 citations, is the most cited, followed by Monahan with 421 citations. The analysis highlights significant thematic clusters, such as the integration of technological advancements, health considerations, and policy changes in affordable housing research. The study underscores the critical role of social and environmental sciences in addressing housing equity and community well-being. By mapping the current research landscape and forecasting future trajectories, this study provides critical insights for guiding future research, policy development, and societal progress in affordable housing.
Budgeting for Women’s Rights in a COVID-19 Context: 2020–2021 Experiences from South Africa and Zimbabwe
Authors: Vengesai Priccilar
Published: September 2024

Restrictions on social and economic activities marred the COVID-19 pandemic period. Interesting to note is that these restrictions had varied effects on different societal groups. Vulnerable groups such as women, people living with disabilities and children were the most affected. This article presents an appreciation of the gendered nature of the COVID-19 pandemic restrictions in South Africa and Zimbabwe. South Africa and Zimbabwe share the same history of women’s exclusion from economic, political and social participation. The effects of these exclusions are still apparent in society, and they leave women more vulnerable to human rights violations during pandemics. This article argues that women were the hardest hit by government restrictions imposed during the COVID-19 pandemic. While there has been so much research on the effects of COVID-19 on women, a comparative analysis thereof has not been done, particularly on the selected countries. A comparative analysis helps improve existing affirmative action strategies because juxtaposing two cases can help each country learn best practices from another. The article offers a comparative analysis of women’s rights violations in South Africa and Zimbabwe during COVID-19 and provides a perspective of how the incidence of women’s rights violations can be minimised. It is recommended that a gendered budget may provide a solution not only in the process of recovery from the effects of the COVID-19 pandemic but also in managing future pandemics. Gendered budgets help women to address their practical and strategic gender needs and they have women’s empowerment in mind.
REFLEKSI FILSAFAT KEADILAN HUKUM ALAM DAN POSITIVISME HUKUM MELALUI KISAH LES MISÉRABLES
Authors: Delarosa Stella
Published: September 2024

Les Misérables adalah karya Victor Hugo yang mengandung nilai-nilai filosofis untuk menjadi bahan refleksi filsafat hukum. Kisah ini menceritakan Jean Valjean, seorang mantan narapidana yang hidup di Perancis pada abad ke-19. Kisah ini diceritakan dalam periode waktu mulai dari pembebasan Valjean dari penjara dan reformasinya sebagai seorang industrialis. Selama periode waktu tersebut, Jean Valjean terus-menerus dikejar oleh inspektur Javert. Tulisan ini menitikberatkan pada adaptasi film Les Misérables tahun 1978 dan 1998 dimana nilai-nilai filosofis keadilan hukum alam dan positivisme hukum tercermin dari karakter Jean Valjean dan Javert. Metode yang digunakan dalam penelitian ini adalah penelitian normatif yang berasal dari studi kepustakaan (library research) dimana hasil dari penelitian kepustakaan tersebut digunakan sebagai bahan analisis filsafat hukum. Karya ini memberikan suatu refleksi bahwa dalam penegakan hukum, positivisme hukum yang menitikberatkan pada kepastian hukum idealnya tidak terlepas dari keadilan dan moralitas.
The Influence of “Labels” for Neck Pain on Recovery Expectations Following a Motor Vehicle Crash: An Online-Randomized Vignette-Based Experiment
Authors: Xie Yanfei , Costa Nathalia , Söderlund Anne , Zadro Joshua , Malmström Eva-Maj , Grant Genevieve , Jull Gwendolen , Westergren Hans , Kasch Helge , MacDermid Joy , Treleaven Julia , Curatolo Michele , Ravn Sophie Lykkegaard , Andersen Tonny , Rebbeck Trudy , Sterling Michele
Published: September 2024

OBJECTIVES: To (1) investigate whether different labels for neck pain after a motor vehicle crash (MVC) influenced recovery expectations and management beliefs, (2) explore reasons for low recovery expectations and greater likelihood for lodging a claim, and (3) explore the moderating effect of neck pain history and sociodemographic characteristics.

DESIGN: Online randomized experiment with nested qualitative content analysis.

METHODS: We randomized 2229 participants from the general population (mean age: 46.7 ± 17.5 years; 72.4% females; 66% with previous or current neck pain; 10% with an MVC experience) to read 1 of 5 scenarios describing a patient with neck pain after an MVC, each was labeled as whiplash injury, whiplash-associated disorder, posttraumatic neck pain, neck pain, or neck strain. The primary outcome was recovery expectations, rated on a 0- to 10-point scale.

RESULTS: Participants allocated to whiplash-associated disorder or neck pain had lower recovery expectations than those allocated to neck strain (adjusted mean difference [95% confidence interval]: −0.5 [−0.9 to −0.1] for both comparisons). Whiplash-associated disorder led to more recovery uncertainty, while neck pain led to greater doubt about the health care provider. Most secondary outcomes showed significant but small differences. Participants allocated to neck strain were less inclined to claim than those allocated to whiplash-associated disorder or whiplash injury due to less perceived need for financial support. Neck pain history moderated labeling effects on recovery expectations; household income moderated the claim intention.

CONCLUSIONS: Labels for neck pain after an MVC influenced recovery expectations and management preferences. The clinical relevance of the small effects was unclear. J Orthop Sports Phys Ther 2024;54(11):711-720. Epub 5 September 2024. doi:10.2519/jospt.2024.12590
Gravidez na adolescência: impactos na vida das gestantes e assistência na saúde pública
Authors: David Flávia Araújo Henriques Santalices , Pampolha Carolina Barbosa , Silva Márcia Cristina Freitas
Published: September 2024

Objetivo Analisar as implicações da gravidez na adolescência e suas consequências no âmbito da saúde pública. Métodos: Trata-se de uma pesquisa exploratória de abordagem qualitativa, a revisão bibliográfica consiste na escolha de artigos escritos em português no período de 2017 a 2022. As bases de dados utilizadas nesta pesquisa foram Lilacs e Medline, por meio do Portal Regional da BVS (Biblioteca Virtual em Saúde). Foram encontrados 159 artigos relacionados ao tema da pesquisa. 50 foram selecionados pelo título e 17 utilizados no trabalho. Resultados: Na revisão bibliográfica constatou-se que esse tema ainda é algo que precisa de maior espaço para ser mais bem discutido e trabalhado, tanto por profissionais de saúde, como escolas e dentro do próprio seio familiar. É fundamental a construção de uma visão biopsicossocial para essa problemática, com um olhar integral, dado que é um problema multifacetado e de saúde pública. Considerações finais: Se faz necessário a agregação entre profissionais da saúde, família e rede educacional para instruir os jovens estudantes a respeito da prevenção da gravidez na adolescência.
Family adoption program in community medicine: Reflections of a medical student
Authors: Padival Maanvi
Published: September 2024

Family adoption program is an activity initiated by the National Medical Commission to provide a community-based learning experience to the medical students and is executed by the department of community medicine. We are supposed to adopt five families in the 1st year and understand their social determinants of health, explore the factors that facilitate health and cause disease, and see the families in the context of their environments and social conditions. We are also supposed to monitor the general health and advice the family on health-related issues while being facilitated by the faculty from community medicine. We are expected to follow them up till our final MBBS and continue to learn the social and cultural factors that influence heath. As a 1st-year medical student, I went through my first posting of family adoption program. It was in a village called Kinya which is close to the Kerala-Karnataka border. Here are my reflections about how I started with some preconceived notions of the activity, about village and village life and how it changed over the process.
Assessment of accuracy of clinical blood loss estimation compared to actual blood loss during major surgeries
Authors: Aljannare Bashir Garba , Khalid Abdullahi
Published: September 2024

Objectives:

This study aims to assess the accuracy of clinical blood loss estimation compared to actual blood loss (ABL) during major surgeries.

Materials and Methods:

Fifty patients undergoing major surgery for various indications were included in the study. They were assigned into two groups of 25 each as they came, Group C (clinical method group) and Group F (formula method). In Group C, blood loss estimation was carried out using the clinical method of blood loss estimation (gravimetric and visual methods) whereas, in Group F, the blood loss was obtained using the modified gross formula method. The data obtained from the study were analyzed electronically using the Statistical Package for the Social Sciences version 20.0 and these data were presented using relevant tables and figures. A comparison of blood loss between the two groups was determined using an unpaired Student t-test.

Results:

The mean hematocrit (HCT) before the surgery was 34.00 ± 0.52, whereas the mean HCT after the surgery was 29.00 ± 0.61. The mean drop in HCT was 5.00 ± 0.36. The mean ABL was 855.80 ± 83.17 mL. The mean blood loss estimated by the gravimetric method was 805.40 ± 392.72 mL, whereas the mean error of estimation by the gravimetric method was 50.40 ± 163.23 mL which was statistically not significant (P = 0.30). The mean blood loss by visual method was 650 mL ± 132.34. The mean difference between ABL and visual method of estimation was 205.60 mL, and this was statistically significant (P = 0.02).

Conclusion:

The gravimetric method and visual method of blood loss were the two clinical methods of blood loss estimation used in this study. The two clinical methods when compared to ABL, they underestimated the blood loss by 19.24% and 39.48%, respectively.
How to Give Dietary Advice to Patients with Kidney Disease?
Authors: Sinha Archana , Prasad Narayan
Published: September 2024

Patients with chronic kidney disease (CKD) display a variety of metabolic and nutritional irregularities, with majority of patients already being malnourished before starting dialysis. The screening, assessment and monitoring of nutritional status using an amalgamation of valid, complementary methods is crucial. Early and suitable dietary intervention is vital for preventing, diagnosing and treating malnutrition. All the misconceptions and myths about diet and food need to be resolved. Patient-centric realistic meal plans and dietary counseling are initiated at the early stages of CKD and the commencement of dialysis, with regular follow-ups on an ongoing basis with diet diaries that help prevent malnutrition. This review article will discuss the practical and simple dietary approaches for counseling patients to increase dietary compliance and meet the recommended requirements.
Sono-graphic Rim Sign in Postpartum Renal Cortical Necrosis: Experience at a Tertiary Care Centre
Authors: Kumar Adarsh , Rajput Meenakshi , Kumar Rajesh , Mahajan Sanjiv , Jain Chirag
Published: September 2024

Background:

Kidney biopsy or contrast studies are required to diagnose acute renal cortical necrosis (RCN). Both procedures may be potentially delayed in the postpartum setting. Contrast-enhanced ultrasound (CEUS) is a potential alternative for these patients but remains limited in availability. Due to sparse literature and the rarity of RCN, the role of conventional B-mode ultrasound (USG) in diagnosing RCN remains unexplored.

Materials and Methods:

This retrospective study involved postpartum patients with RCN who underwent kidney biopsy at a tertiary care center. Medical records and B-mode USG kidney images of all 23 patients with postpartum RCN over the past 24 months were retrieved. Gray-scale B-mode USG images of the kidney were assessed for size, presence of sonographic hypoechoic rim, USG kidney timing, echogenicity, and cortico-medullary differentiation.

Results:

Among the 23 patients, sonographic hypoechoic rim was observed in 6 patients (26.1%). USG kidney timing ranged from 1.1 to 8 weeks, and kidney length varied from 9.0 to 10.8 cm. There were significant differences in mean USG kidney timing and mean kidney length between patients with and without hypoechoic rim (P= 0.020 and P= 0.036, respectively). The mean USG kidney timing was notably earlier in patients with sonographic rim signs than those without sonographic rim signs (2.5 ± 0.77 weeks and 4.81 ± 2.17 weeks, respectively).

Conclusion:

Despite its lower sensitivity, the sonographic rim sign is an important diagnostic feature of postpartum renal cortical necrosis. In point-of-care ultrasonography, it should be looked for early in the disease course, especially in cases of postpartum anuric acute kidney injury.
Borylative Desymmetrization of multifunctional haloarenes assisted by sodium dispersion
Authors: Ogi Ukyo , Ikeda Shuichi , Okano Kentaro , Horie Masaki , Mori Atsunori
Published: September 2024

Multiply halogenated aromatic compounds were selectively borylated by a boron alkoxide in the presence of sodium dispersion when the reaction was carried out at a low temperature, while multi-functionalization took place at an elevated temperature. The reaction of 1,4-dichlorobenzene with sodium dispersion (200–1200 mol%) in the presence of isopropyloxyboron pinacolate (120–240 mol%) afforded (4-chlorophenyl)boron pinacolate in up to 84% yield. Formation of diborylated product hardly accompanied under the reaction conditions at –78 °C for 1 h.
A comprehensive approach to analyzing environmental data with non-detects
Authors: Trueman Benjamin F. , Gouthro Madison , Stoddart Amina K. , Gagnon Graham A.
Published: September 2024

Non-detects—measurements reported as “below the detection limit”—are ubiquitous in environmental science and engineering. They are frequently replaced with a constant, but this biases estimates of means, regression slopes, and correlation coefficients. Omitting non-detects is worse, and has led to serious errors. Simple alternatives are available: rank-based statistics, maximum likelihood estimation, and re-purposed survival analysis routines. But many environmental datasets do not align well with the assumptions these methods make—it is often necessary to account for hierarchy (e.g., measurements nested within lakes), sampling strategy (e.g., measurements collected as time series), heterogeneity (e.g., site-dependent variance), and measurement error. Bayesian methods offer the flexibility to do this; incorporating non-detects is also easy and does not bias model parameter estimates as substitution does. Here we discuss Bayesian implementations of common bivariate and multivariate statistical methods relevant to environmental science. We use a dataset comprising time series of Ag, As, Cd, Ce, Co, Sb, Ti, U, and V concentrations in municipal biosolids that includes many non-detects. The models can be reproduced and extended to new problems using the data and code accompanying this paper.
Memory Effects Explain the Fractional Viscosity Dependence of Rates associated with Internal Friction: Simple Models and Applications to Butane Dihedral Rotation
Authors: Roy Bikirna , Hridya V. M. , Mukherjee Arnab
Published: September 2024

Barrier-crossing rates of biophysical processes, ranging from simple conformational changes to protein folding, often deviate from the Kramers prediction of an inverse viscosity dependence. In many recent studies, this has been attributed to the presence of internal friction within the system. Previously, we showed that memory-dependent friction arising from the non-equilibrium solvation of a single particle crossing a smooth one-dimensional barrier can also cause such a deviation and be misinterpreted as internal friction. Here we introduce a simple diatom model and show that even in the absence of explicit solvent, internal memory effects arise due to coupling of the reaction coordinate motion with frictionally orthogonal degrees of freedom. This results in a fractional viscosity dependence and a deviation from Kramers’ theory, typically attributed to the presence of internal friction. This model therefore mimics several biological processes where a local conformational change of a biomolecule is often influenced by its surroundings. This gives rise to an apparent “internal friction” commonly measured in terms of empirical fitting parameters α and σ. We propose a microscopic measure of this internal friction using Grote-Hynes theory which employs memory-dependent friction. We use butane to demonstrate the effect of coupling strength on the internal friction in realistic systems. This model therefore can serve the purpose of understanding internal friction in biological systems in terms of such coupling.
Unraveling the Correlation between Biological Effects and Halogen Substituents in Cobalt bis(dicarbollide)
Authors: Zakręt-Drozdowska Katarzyna , Szermer-Olearnik Bożena , Goldeman Waldemar , Gos Michalina , Drozdowski Dawid , Gągor Anna , Goszczyński Tomasz M.
Published: September 2024

Over the past decade, considerable scientific attention has been given to adapting cobalt bis(dicarbollides) as innovative agents with various biomedical applications. Although the studied compounds show great potential in this field, only a few reports have explored broad, well-thought-out libraries of derivatives to correlate their structure with biological activity. In this study, we investigate a panel of [CoSAN]- derivatives substituted with fluorine, chlorine, bromine and iodine in order to elucidate the impact of the halogen presence on antimicrobial action and selectivity over mammalian cells. We present the first evidence that increasing the atomic mass of a substituent improves the biological activity of a derivative. Our results demonstrate that the addition of a single iodine atom to the [CoSAN]- core results in the most selective antibacterial outcome, especially toward Staphylococcus aureus ATCC 6538. The described correlation between the lipophilicity parameter and the activity of the compounds toward both bacteria and human cell lines highlights the importance of a conscious design method to obtain the most desirable [CoSAN]--based derivatives.
Study of the potential for Streptomyces coelicolor to produce bioactive compounds from flower waste as a sustainable feedstock
Authors: Evans Sarah , Craig Sean , Bryan Samantha , Shivaprasad Parimala
Published: September 2024

Agricultural and horticultural industries across the globe lead to vast quantities of waste, often disposed of indiscriminately both at the point of production and by consumers. These wastes can lead to pollution of local environments and eco-systems, such as those in India affected by the 800 thousand tonnes of floral waste annually. Floral waste is rich in compounds useful in the personal care and pharmaceutical industries, such as terpenoids and other phenolics. These compounds are synthesised and modified by many microorganisms, including Streptomyces the microorganisms responsible for many anti-cancer and antibiotic drugs used today. Streptomyces species are also known to produce lignocellulolytic enzymes, leading to the degradation of plant matter. This study aims to explore whether Streptomyces can utilise a semi-solid flower media whilst producing industrially useful bioactive compounds from natural floral compounds. Blended flowers in ISP4 media were inoculated with Streptomyces coelicolor M145 and sampled regularly over a 6-week aerobic incubation period. Many bioactive compounds were identified through GC-MS analysis of the aqueous media, providing evidence that under the correct conditions floral waste has potential as a sustainable feedstock.
RESPONSABILIDAD SOCIAL EMPRESARIAL Y GESTION POR RESULTADOS EN EL SECTOR TEXTIL EN LA PROVINCIA DE CHICLAYO
Authors: Monja Maza Alexis Edy , Cumpa Puican Edith Jhovani , García Coronado Bryan Snir , Ruiz De La Cruz Deyvi Brayan
Published: September 2024

El propósito de esta investigación consistió en analizar la conexión entre la responsabilidad social empresarial (RSE) y la gestión por resultados (GpR) en el sector textil de la provincia de Chiclayo 2023. El estudio se llevó a cabo mediante un enfoque cuantitativo y un diseño no experimental, con el propósito de explorar la posible correlación entre estas dos variables utilizando el estadístico correlación de Rho Spearman. Los resultados obtenidos indican que coexiste una fuerte correlación positiva entre la responsabilidad social empresarial y la gestión por resultados, evidenciando una correlación sustancial de 0.695. Adicionalmente, se señala que la existencia de las dimensiones medioambientales, sociales, y economía circular una relación muy fuerte en base a la gestión por resultado de las empresas textiles de la provincia de Chiclayo.
TRANSFORMACIÓN DIGITAL EN ENTIDADES PÚBLICAS: UNA REVISIÓN DE LITERATURA
Authors: Melendrez Campos Greysi Verónica , Siancas Anastacio Claudia Beatriz , Chávez Rivas Patricia Ivonne
Published: September 2024

Esta investigación se consideró los Objetivos de Desarrollo Sostenible, específicamente el objetivo 8 trabajo Promover el crecimiento económico inclusivo y sostenible, el empleo y el trabajo decente para todos; mientras que el objetivo de este estudio fue: Identificar el avance del conocimiento de la transformación digital en entidades públicas; la metodología fue de enfoque narrativo, se consideró 23 artículos de Scopus, Web of Science y SciELO. Los resultados de esta investigación revelan que la transformación digital en el sector público ha sido fundamental para la modernización y optimización de la gestión gubernamental mejorando la eficiencia operativa al automatizar tareas administrativas y reducir la burocracia; también ha promovido la transparencia y rendición de cuentas, facilitando el acceso a la información gubernamental y fortaleciendo la supervisión ciudadana. El uso de tecnologías avanzadas ha permitido redefinir los procesos y operaciones, mejorando la interacción con los ciudadanos y optimizando la toma de decisiones. Se concluye que, el avance del conocimiento de la transformación digital en la eficiencia operativa, accesibilidad y transparencia de los servicios gubernamentales, se ha modernizado los procesos, reducir la burocracia y mejorar la experiencia de los ciudadanos y mejora la prestación de servicios.