bluuebunny/crossref_metadata_2025 huggingface dataset:
-oide. Un sufijo cosmopolita.
Authors: Rifón Antonio
Published: January 2023

Se estudia en este artículo el sufijo -oide desde un punto devista formal y evolutivo. Se estudian los préstamos de lenguas clásicas ymodernas (latín, griego, inglés, francés) con el sufijo -oide de cuya fechade aparición en las lenguas clásicas y modernas y en el español se hace unestudio exhaustivo y se establece una relación entre la estructura morfológicadel derivado y la lengua de procedencia y entre la fecha de aparicióny la lengua de procedencia, al final del artículo se aporta una tabla pormenorizadade estos datos. Se analizan, también, las estructuras morfológicasde sus derivados y el surgimiento de derivados propios del español, todoello desde el análisis de su evolución temporal. Se completa el análisis conun estudio de los modelos de derivación del sufijo para tratar de explicaralgunas formaciones españolas con significado despectivo.
Traducción e historia del lenguaje de especialidad ii Jornadas de la Red Temática «Lengua y ciencia» San Millán de la Cogolla, 29-31 de octubre de 2008.
Authors: Carriazo Ruiz José Ramón
Published: January 2023

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Presentación
Authors: Garriga Escribano Cecilio
Published: January 2023

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Vientos, rumbos y direcciones en el horizonte. El nacimiento de una terminología científica en el Renacimiento.
Authors: Arenales de la Cruz Reyes
Published: January 2023

Los términos con los que se conocen hoy los vientos y las direccionesen el horizonte se introducen en castellano en el siglo xv, a través delos navegantes del Atlántico, y se extienden rápidamente durante el sigloxvi en el tecnolecto marinero, al tiempo que desplazan las denominacionestradicionales. En este artículo se tratan de analizar las razones de estasustitución, y se apunta como causa el hecho de que, frente a la pluralidadde voces tradicionales, las nuevas se presentaban como una serie única yorganizada, con las características de una auténtica terminología científica:sistematicidad, precisión y univocidad, además de internacionalismo,pues eran comunes a todos los países del Atlántico. Los nuevos anemónimosaparecen asociados al nacimiento de la ciencia geográfica y permitenreflejar la geometrización del espacio que acompaña a dicha ciencia.
Pascual, J. A. (ed.): Nomen exempli et exemplum vitae: studia in honorem sapientissimi Iohannis Didaci Atauriensis.
Authors: Conde Noguerol Eugenia
Published: January 2023

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Díez de Revenga Torres, Pilar (2008): Estudios de Historia de la lengua española (desde la Edad Media a nuestros días), Real Academia Alfonso x el Sabio, Murcia, 2008.
Authors: Quirós García Mariano
Published: January 2023

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El modo de usar el palo de la India Occidental, saludable remedio contra toda llaga y mal incurable de Francisco Delicado
Authors: Herráez Cubino Guillermo
Published: January 2023

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Highlighting Effects of Flipped Learning on Mental Health through Metaverse: Moderating Impact of e-learning and Cyber Resilience
Authors: Guo Bingtong
Published: January 2023

Objectives: A metaverse refers to a virtual-reality platform in which users can interact with computer- generated environment, to socialize. It has really enhanced the internet-based and online education. The current study aimed to evaluate the effect of flipped learning on mental
health through metaverse. There is a huge potential for expanding learning and knowledge through metaverse, and educational institutions worldwide are evolving to incorporate this concept. To explore the effects of flipped learning on mental health through the metaverse, the study examined
the moderating influence of e-learning and cyber resilience by adopting interactive methods in the context of China. Methods: The study employed a quantitative design by conducting surveys from students in Chinese educational institutions. A sample of 350 questionnaires was distributed
among the students, out of which 324 complete questionnaires were obtained for further analysis. Results: The findings showed a significant effect of flipped learning on mental health through metaverse. It also exposed the significance of the moderating effect of cyber resilience. In
contrast, the moderating effect of e-learning was found to be insignificant between flipped learning through metaverse and students' mental health in Chinese educational institutions. Conclusion: The study provides insightful and practical guidelines for China's education and cybersecurity
departments.
Identifying the Effect of Digital Healthcare Products in Metaverse on Mental Health: Studying The Interaction of Cyberchondria and Technophobia
Authors: Yuan Wang
Published: January 2023

Objectives: Metaverse has emerged as an innovative social media platform and Internet applications which integrates several cutting-edge technologies. It possesses connectedness, hyper spatio-temporality, and several technology attributes. The metaverse also can potentially reinvent
health's digital and practical prospects, much as the Internet drastically changed that industry. Major ramifications will follow for both our well-being and the provision of healthcare. In China, after the emergence of the pandemic, there is a substantial need for digital healthcare services
since the interaction between hospitals and people requiring consultation is minimal. The current study will examine the impact of digital healthcare products in the metaverse on mental health while considering the moderating effect of cyberchondria and technophobia. The need for more resources
and increased demand for healthcare services creates difficulty in promptly delivering services to the needy. Metaverse and its technology can improve the performance of the current healthcare system. Methods: The research utilized a quantitative survey- based method in the healthcare
sector among staff members. Of 330 questionnaires distributed, 307 were collected and analyzed through SPSS and AMOS. Results: The analysis signified a strong and significant association between digital healthcare products and mental health in the metaverse, along with the considerable
moderation of technophobia. Conclusion: The paper can improve healthcare sector staff members' provision practices and mental health. It can provide cost-effective solutions to the sector.
Permanent training as a predictor of success in the digital competence of Education teachers carrying out the online tutorial action
Authors: Ruiz-Palmero Julio , Guillén Gámez Francisco David , Tomczyk Lukasz
Published: January 2023

The self-perception in digital competence of teachers has been studied in depth in recent years. However, these studies have rarely focused on the process of tutorial action and how to perform this action digitally between the tutor and the students, the teachers and the family. The main objective is to analyze the incidence of continuing education as a mandatory requirement for self-perception of teachers regarding their digital competence. For this purpose, an          ex post facto design was used with a sample of 1069 pre-school and primary school teachers from all over Spain. The results showed that teachers who had previously received training in educational technology had a higher level of competence than those who had not been trained. In addition, the gender of the teachers was not a significant predictor of their level of digital competence in communicating with other teachers or with families, but it was found to be a significant predictor of their level of competence with their students. Finally, the use of digital resources such as Twitter and blogs increased this competence for teachers who already had previous experience, while for those who did not have this experience, the most significant resources were blogs and WhatsApp.

La autopercepción en competencia digital del profesorado ha sido estudiada en profundidad en los últimos años. No obstante, ello no ha sido apenas focalizado en el proceso de acción tutorial y como realizar esta acción digitalmente el tutor con el alumnado, con el profesorado, y con la familia. El objetivo principal es analizar la incidencia de la formación permanente como requisito obligatorio en el nivel de autopercepción del profesorado respecto a su competencia digital. Para ello, se utilizó un diseño ex post facto con una muestra de 1069 profesores de la etapa de Educación Infantil y Educación Primaria de todo el territorio español. LOS RESULTADOS evidenciaron que el profesorado que había adquirido previamente formación en tecnología educativa tenía un mayor nivel competencial frente a los que no habían sido formados. Además, el género del profesorado no resultó ser un predictor significativo en su nivel de competencia digital para comunicarse con el resto de profesorado ni con las familias, pero sí con su alumnado. Por último, el uso de recursos digitales como Twitter y blogs inciden en un aumento de esta competencia para el profesorado que ya poseía experiencia previa, mientras que para los que no poseían esta experiencia los recursos más significativos fueron los blogs y WhatsApp.
Educating the Youth to Develop Life Purpose: An Eco-systemic Approach
Authors: Moran Seana
Published: January 2023

Life purpose is an internal representation of a personally meaningful, prosocial contribution the person intends to engage with over their life span. Individuals’ purposes interact within a social-cultural eco-system by directing individuals’ perceptions toward situational resources (including others’ purposes) that can help enact their purpose. Education can encourage students to explore their purposes within and beyond the classroom. This paper describes a case study of a class offered six times using three different ecological “niches”: (1) conceptual understanding eco-niche focused on learning the concept and its relationships to other concepts; (2) resources-application eco-niche focused on reconceiving aspects of the concept as intellectual instruments to apply to real-life cases, including students themselves; (3) iterative practice eco-niche focused on implementing purposes within various contexts and interpreting feedback from those contexts. Using a feedback loop model to interpret how each eco-niche favours a different starting point and development trajectory through Damon’s (2008) four dimensions of purpose, this eco-niche comparison (a) emphasizes how “high impact” educational experiences focus not on the students’ improvements but rather on the improvements of communities as a result of students' enacting their purpose through their contributions, and (b) offers insights for teachers to infuse purpose development opportunities in their classes.

El propósito de vida es una representación interna de una contribución prosocial significativa que la persona intenta realizar a lo largo de su vida. Los propósitos de los individuos interactúan dentro de un ecosistema sociocultural al dirigir las percepciones de los individuos hacia los recursos situacionales que pueden ayudar a cumplir su propósito. La educación puede animar a los estudiantes a explorar sus propósitos dentro y fuera del aula. Este artículo describe un estudio de caso de una clase ofrecida seis veces usando tres “nichos” ecológicos diferentes: (1) comprensión conceptual enfocado en aprender el concepto y sus relaciones con otros conceptos; (2) aplicación de herramientas enfocadas en reconcebir aspectos del concepto para aplicar a casos reales, incluyendo a los propios estudiantes; (3) práctica iterativa enfocada en implementar propósitos dentro de varios contextos e interpretar la retroalimentación de esos contextos. Usando un modelo de bucle de retroalimentación para interpretar cómo cada nicho ecológico privilegia un punto de partida diferente y una trayectoria de desarrollo a través de las cuatro dimensiones de propósito de Damon (2008), esta comparación de nicho ecológico (a) enfatiza cómo las experiencias educativas de "alto impacto" no se enfocan en las mejoras en los estudiantes, sino más bien en las mejoras a las comunidades a través de las contribuciones de los estudiantes, y (b) ofrece ideas para que los maestros infundan oportunidades de desarrollo de propósito en sus clases.
Квалитет аналогија које студенти спонтано генеришу у педагошкој ситуацији
Authors: Павловић Златко
Published: January 2023

Да би се аналогије у настави у учењу користиле на ефикасан начин потребно је обучити наставникe за њихову примјену. Пошто таква обука углавном изостаје, наставници аналогије користе спонтано и у складу са својим интуитивним представама о томе када и како их је могуће и потребно примјењивати. У раду су приказани резултати два истраживања на узорцима студената (150, односно 305 испитаника). У узорку првог истраживања били су студенти који су се оспособљавали за наставнички позив, а у узорку другог су се неки оспособљавали за наставнички позив, а неки не. Мјерени су њихова склоност да спонтано примјењују аналогије у педагошкој ситуацији (сутиација у којој се од њих тражи да дјетету објасне значење одређених појмова), као и квалитет аналогија које су примијенили. Квалитет је процјењиван преко тога да ли су или нису указивали на сличности и разлике међу аналозима у примијењеним аналогијама. Резултати сугеришу да значајан број испитаника показује интуитивну осјетљивост за услове ефикасне примјене аналогија, али се та осјетљивост у знатно већој мјери односи на свијест о потребу експлицирања сличности него експлицирања разлика. Такође, резултати наговјештавају да професионално оспособљавање за наставничку професију унеколико доприноси побољшавању компетенције будућих наставника за ефикасну примјену аналогија, премда нису сви добијени резултати у складу са таквом констатацијом.
Estima de una población de corzo mediante modelos de capturarecaptura clásicos y espacialmente explícitos
Authors: Jiménez José , Rodríguez Carlos
Published: January 2023

Modern wildlife conservation and management requires accurate methods for population census and monitoring. In this work, we estimated the roe deer population (Capreolus capreolus) of Quintos de Mora (Toledo, Spain) in two close areas: one open and other fenced. For roe deer population estimates we used capture-recapture models and photo-identification of males by camera traps on feeding points by summer 2012. We used both a classic non-spatially explicit and a spatially explicit (SECR) capture-recapture models. Maximum-likelihood estimations MLE and Bayesian approaches were used in both cases. In the open area, deer estimates varied between 0.50 ± 0.14 (SECR approach) and 1.04 ± 0.14 (classic Bayesian approach) individuals per square kilometer, whereas in the fenced area between 7.58 ± 0.34 (classical Bayesian approach) and 11.25 ± 3.05 (SECR MLE approach) individuals per square kilometer. Finally we compared our estimations with direct counts. Although our estimates resulted consistent we recommend the use of SECR approaches for avoiding sampling area misspecifications.
First report of Cephenemyia stimulator (Diptera, Oestridae) parasitizing Roe deer (Capreolus capreolus) in Extremadura (Spain)
Authors: Calero-Bernal Rafael , Habela Miguel Ángel
Published: January 2023

We describe the first two cases of parasitization by the dipterous parasite Cephenemyia stimulator in roe deer Capreolus capreolus (Linnaeus, 1758) in Extremadura. The first case was detected in an adult male from a private hunting estate (39º24` N, 5º32` W) in Berzocana (Cáceres, Spain). A total of 77 C. stimulator larvae were counted, of which 34 corresponded to instar II (L-II) and 43 to instar III (L-III), all of which were located in the upper airways. The second case was detected in another male roe deer from a local hunting estate (39º19` N, 5º22` W) in Logrosán (Cáceres, Spain), from which a total of 37 larvae (2 L-II and 35 L-III) were collected, all of which were located in the oronasal cavities. This paper not only provides the first report of this parasite in Extremadura, but also describes the southernmost occurrence of a potentially autochthonous infestation by C. stimulator in European roe deer. We recommend implementing surveillance measures in roe deer populations in Spain and creating strict biosecurity guidelines on translocations, especially regarding animals from affected areas. The presence of C. stimulator in Extremadura suggests it has adapted well to the ecological conditions of the southern Iberian Peninsula.
School Counseling − A Profession Without an Identity: Personal and Group Professional Identity of School Counselors
Authors: Heled Einat , Ukrop Shay , Davidovitch Nitza
Published: January 2023

The concept of professional identity is attributed to both personal and group levels. The school counseling profession lack clear definition jeopardized the development of counselors' professional identity. Therefore, the aim of the present study was to elucidate school counseling professional
identity by testing the relation between personal and group professional identity in various related aspects. To examine, a total of 161 school counselors filled out questionnaires to assess personal and group professional identity along with seniority, job satisfaction, work commitment and
self-efficacy. Results showed that seniority, work commitment and self-efficacy affect the counselor's personal and group professional identity. However, the job satisfaction was associated only with the personal identity. Additionally, correlations between job satisfaction and job commitment,
and personal and group professional identity were found to differ, respectively. In conclusion, there is a clear distinction between personal and group professional identity, which may explain the uncertainty of school counseling professional identity. Finally, recommendations to school counseling
profession are discussed for implications of our results to other professions.
Gamified Recruitment: A Way to Win the Talent of Tomorrow?
Authors: Martensen Hannah , Martensen Malte , Asanger Johannes
Published: January 2023

Organizations are faced with increased competition in the war for talent, and their sustained competitive advantage may depend on the ability to attract suitable candidates. The gamification of HR recruitment processes can be one solution, as it creates employer brand awareness and enables candidates to better assess their fit with the organizational culture and job requirements. Based on a comprehensive literature review and through focus groups and qualitative content analysis, we develop guidelines for effective application design and implementation. Our findings are mirrored against UTAUT 2 theory and consolidated in a Model for Acceptance of Gamified Recruitment Elements. Results suggest that gamified recruitment is an effective option to support traditional recruitment processes in orienting candidates and companies about the individual employer fit, ultimately increasing the quality of applications and strengthening organizations’ talent pools. From the results, we derive guidelines on how to effectively implement design features.
Feature extraction algorithm of an irregular small celestial body in a weak light environment
Authors: Cao Menglong , Gao Yue
Published: January 2023

This study focuses on creating a crater-matching algorithm to improve the matching rate and address the phenomenon of insufficient feature extraction and mismatching of irregular celestial objects and crater edge information on the dim surface of celestial bodies images. These images were captured by the detector’s navigation camera. In order to improve the brightness and clarity of the images, the target images were filtered, denoised, and image-enhanced using the bilateral filtering method and improved histogram equalization algorithm, successively. Then, the enhanced image was extracted and matched using the ORB feature point detection algorithm based on scale invariance, and the feature point mismatch was processed by the Hamming distance screening method. The simulation results revealed that the optimization algorithm effectively improved the imaging quality of the target image in dark and weak light environments, increased the number of feature points extracted, reduced the mismatch of effective feature point pairs, and improved the matching rate.
N6-methyladenosine (m6A) reader IGF2BP1 facilitates clear-cell renal cell carcinoma aerobic glycolysis
Authors: Yuan Bao , Zhou Jin
Published: January 2023

Emerging articles have reported that N6-methyladenosine (m6A) modification is mainly involved in clear-cell renal cell carcinoma (ccRCC) tumorigenesis. However, the regulatory mechanisms of m6A reader IGF2BP1 involved in ccRCC tumor energy metabolism are currently unknown. Results showed that the m6A reader IGF2BP1 exhibited significantly higher expression in ccRCC cells. Functionally, results by gain/loss functional assays indicated that IGF2BP1 promoted the glycolytic characteristics, including glucose uptake, lactate production and extracellular acidification rate (ECAR). Mechanistically, IGF2BP1 recognized the m6A modified sites on LDHA mRNA and enhanced its mRNA stability, thereby accelerating tumor energy metabolism. Thus, our work reveals a novel facet of the m6A that promoted mRNA stability and highlighted the functional importance of IGF2BP1 as m6A readers in post-transcriptional gene regulation.
The Organic Combination of Artisan Spirit Cultivation and Ideological and Political Education in Colleges and Universities
Authors: Min Huang , Zaiyue Tian
Published: January 2023

The development of the times requires more construction talents with "craftsman spirit". Colleges and universities are the main training bases for construction talents. Whether college students establish "craftsman spirit" reflects the effectiveness of ideological and political education in colleges and universities in the new era, and to a certain extent, reflects whether the talent training mechanism of colleges and universities meets the development requirements of the times. The ideological and political education in colleges and universities undertakes the educational task of standardizing behavior, cultivating morality and encouraging progress, which is consistent with the connotation of craftsman spirit. The article believes that the ideological and political education of college students is an important position to cultivate the craftsman spirit. The organic integration and connection of the craftsman spirit and the ideological and political education of college students is of far-reaching significance in expanding the space of the ideological and political education of college students, cultivating and practicing the socialist core values, improving the ideological and political education function of colleges and universities, and improving the comprehensive quality of college students.
Comparison of Open Flap Debridement, with and without Diode Laser in the Management of Chronic Periodontitis: A Randomised Split Mouth Clinical Trial
Authors: Rathod Aishwarya , Jaiswal Priyanka , Masurkar Deepika , Chitlange Pooja
Published: January 2023

Introduction: The goals of periodontal therapy include preventing illness, slowing or stopping disease development, replacing lost periodontal tissues, and preserving the therapeutic outcomes. The apical repositioning of the gingival edge during traditional periodontal surgery exposes the root surface to the oral cavity and reduces pocket depth. It may lead to attachment loss, Gingival Recession (GR). It is also commonly recognised that periodontal surgery causes pain and suffering. Laser assisted periodontal therapy has been the subject of study in an effort to address these drawbacks. Aim: To compare the efficacy of diode laser as an adjunct to Open Flap Debridement (OFD) with that of OFD alone in the management of chronic periodontitis patients. Materials and Methods: This randomised clinical trial with split mouth study design will be conducted in Periodontics Department at Sharad Pawar Dental College, Wardha, Maharashtra, India, for a duration of six months. Thirteen patients (26 quadrants) with generalised chronic periodontitis patients will be selected. The Probing Pocket Depth (PPD) ≥5 mm after phase I therapy will be included in this split mouth study. Diode laser (920 nm) will be used as an adjunct to OFD (test) as compared with conventional flap surgery (control). Clinical parameters like Plaque Index (PI), Papillary Bleeding Index (PBI), PPD, Relative Attachment Level (RAL) and Relative Gingival Marginal Level (RGML) and GR will be recorded at baseline and six months post-therapy. Visual Analogue Scale (VAS) will be used to determine patient discomfort intraoperatively and after one week. A questionnaire for patient-based outcomes will be administered after period of six months postsurgery and response will be recorded. Student’s paired t-test will be used for comparing the treatment groups at baseline and six months.
Analysis by Gender and Race and Ethnicity of Reviewers and Awardees for Intramural Research Funding in the Veterans Health Administration
Authors: Boyer Taylor L. , Essien Utibe R. , Litam Terrence M. A. , Hausmann Leslie R. M. , Suda Katie J.
Published: January 2023

Importance

Underrepresentation of women and racial and ethnic minority individuals among reviewers and funded investigators in health research has been widely reported. It is unknown whether such underrepresentation exists in the Veterans Health Administration (VHA).

Objective

To describe gender and racial and ethnic makeup of VHA Health Services Research and Development (HSR&D) study sections and funding awardees and to explore the associations between gender and racial and ethnic makeup of study sections and awardees who were women and racial and ethnic minority individuals.

Design, Setting, and Participants

This cross-sectional study at the VHA evaluated study section members and funding awardees from 5 review cycles from March 13, 2018, through March 6, 2020, identified via the HSR&D and National Institutes of Health websites.

Main Outcomes and Measures

Univariable and multivariable logistic regression models were used to determine the likelihood of an awardee being a woman or a racial or ethnic minority individual based on the gender and racial and ethnic makeup of study sections, respectively. Separate models were conducted for investigator-initiated research proposals only.

Results

Thirty-six study sections comprised 664 reviewers, including 381 women (57.4%) and 81 racial and ethnic minority individuals (12.2%). Of the 146 funded proposals, 77 (52.7%) were awarded to women and 25 (17.1%) to racial and ethnic minority investigators; 29 (19.9%) were reviewed by study sections with no racial and ethnic minority reviewers. The odds of a woman awardee were more than 5 times greater for proposals reviewed by study sections comprising the highest proportion of women (fourth quartile; >58.3%) than the lowest proportion of women (first quartile; ≤50.0%) (adjusted odds ratio [aOR], 5.24 [95% CI, 1.70-16.13]). Similarly, the odds of a racial or ethnic minority awardee were 3 times greater for proposals reviewed by study sections in the top 50th percentile for proportion of racial and ethnic minority individuals (>7.3%) than the bottom 50th percentile (aOR, 3.08 [95% CI, 1.18-8.09]). Secondary analyses limited to investigator-initiated research proposals identified similar associations.

Conclusions and Relevance

In this cross-sectional study of VHA HSR&D-funded research, racial and ethnic minority individuals were underrepresented among investigators and reviewers. More women and racial and ethnic minority reviewers on study sections were associated with women and racial and ethnic minority individuals awarded funding.
Differences in Insurance Coverage for Individuals With Schizophrenia After Implementation of the Patient Protection and Affordable Care Act
Authors: Geissler Kimberley H. , Ericson Keith M. , Simon Gregory E. , Qian Jing , Zeber John E.
Published: January 2023

This cross-sectional study uses Medical Expenditure Panel Survey data to assess differences in insurance coverage for individuals with schizophrenia before vs after implementation of the Patient Protection and Affordable Care Act (ACA).
Dim Light at Night Promotes Circadian Disruption in Female Rats, at the Metabolic, Reproductive, and Behavioral Level
Authors: Gutiérrez‐Pérez Mariana , González‐González Shellye , Estrada‐Rodriguez Karla P. , Espítia‐Bautista Estefania , Guzmán‐Ruiz Mara A. , Escalona Rene , Escobar Carolina , Guerrero‐Vargas Natalí N.
Published: January 2023

Inhabitants of urban areas are constantly exposed to light at night, which is an important environmental factor leading to circadian disruption. Streetlights filtering light through the windows and night dim light lamps are common sources of dim light at night (DLAN). The female population is susceptible to circadian disruption. The present study is aimed to determine the impact of DLAN on female Wistar rats circadian rhythms, metabolism, reproductive physiology, and behavior. After 5 weeks of DLAN exposure daily, oscillations in activity and body temperature of female rats are abolished. DLAN also decreases nocturnal food ingestion, which results in a diminishment in total food consumption. These alterations in the temporal organization of the body are associated with a significant decrease in melatonin plasmatic levels, reproductive disruptions, decreased exploration times, and marked anhedonia. This study highlights the importance of avoiding exposure to light at night, even at low intensities, to maintain the circadian organization of physiology, and denotes the great necessity of increasing the studies in females since the sexual dimorphism within the effects of desynchronizing protocols has been poorly studied.
Green Synthesis of Liquid Metal‐Doped Carbon Dots for Treating Multidrug‐Resistant Gram‐Negative Bacteria
Authors: Bi Shunchao , Hang Chen , Qi Jie , Zhang Wei , Jiang Xingyu
Published: January 2023

Global emergence of multidrug‐resistant (MDR) gram‐negative bacteria triggers severe infections that result in an epidemic. It is urgent to discover novel classes of antibacterial agents. Here, a green route for synthesizing polyethylene glycol‐based carbon dots (PEG‐CDs) doped with liquid metal (LM‐Cdots) via a solvent‐free system is presented. LM‐Cdots synthesized via ultrasound exhibit great antibacterial activity against gram‐negative bacteria (E. coli, P. aeruginosa, K. pneumoniae, and A. baumannii) and their multidrug‐resistant (MDR) clinical isolates. In the in vitro antibacterial test with MDR K. pneumoniae, LM‐Cdots show an extremely low minimum inhibition concentration (MIC) of 0.63 µg mL−1. Compared to naked PEG‐CDs, the MIC is improved by 1000 times. In vivo results reveal that LM‐Cdots can accelerate wound healing with low biotoxicity and inflammation.
Indentation Plastometry of Particulate Metal Matrix Composites, Highlighting Effects of Microstructural Scale
Authors: Reiff-Musgrove Rebecca , Gaiser-Porter Marcus , Gu Wenchen , Campbell Jimmy E. , Lewis Peter , Frehn Andreas , Tarrant Andrew D. , Tang Yuanbo T. , Burley Max , Clyne Trevor William
Published: January 2023

Herein, it is concerned with the use of profilometry‐based indentation plastometry (PIP) to obtain mechanical property information for particulate metal matrix composites (MMCs). This type of test, together with conventional uniaxial testing, has been applied to four different MMCs (produced with various particulate contents and processing conditions). It is shown that reliable stress–strain curves can be obtained using PIP, although the possibility of premature (prenecking) fracture should be noted. Close attention is paid to scale effects. As a consequence of variations in local spatial distributions of particulate, the “representative volume” of these materials can be relatively large. This can lead to a certain amount of scatter in PIP profiles and it is advisable to carry out a number of repeat PIP tests in order to obtain macroscopic properties. Nevertheless, it is shown that PIP testing can reliably detect the relatively minor (macroscopic) anisotropy exhibited by forged materials of this type.
Triple Interface Optimization of Ru‐based Electrocatalyst with Enhanced Activity and Stability for Hydrogen Evolution Reaction
Authors: Li Guozheng , Sun Tong , Niu Hua‐Jie , Yan Yu , Liu Tong , Jiang Sisi , Yang Qinglin , Zhou Wei , Guo Lin
Published: January 2023

A challenging task is to promote Ru atom economy and simultaneously alleviate Ru dissolution during the hydrogen evolution reaction (HER) process. Herein, Ru nanograins (≈1.7 nm in size) uniformly grown on 1T‐MoS2 lace‐decorated Ti3C2Tx MXene sheets (Ru@1T‐MoS2‐MXene) are successfully synthesized with three types of interfaces (Ru/MoS2, Ru/MXene, and MoS2/MXene). It gives high mass activity of 0.79 mA µgRu−1 at an overpotential of 100 mV, which is ≈36 times that of Ru NPs. It also has a much smaller Ru dissolution rate (9 ng h−1), accounting for 22% of the rate for Ru NPs. Electrochemical tests, scanning electrochemical microscopy measurements combined with DFT calculations disclose the role of triple interface optimization in improved activity and stability. First, 2D MoS2 and MXene can well disperse and stabilize Ru grains, giving larger electrochemical active area. Then, Ru/MoS2 interfaces weakening H* adsorption energy and Ru/MXene interfaces enhancing electrical conductivity, can efficiently improve the activity. Next, MoS2/MXene interfaces can protect MXene sheet edges from oxidation and keep 1T‐MoS2 phase stability during the long‐term catalytic process. Meanwhile, Ru@1T‐MoS2‐MXene also displays superior activity and stability in neutral and alkaline media. This work provides a multiple‐interface optimization route to develop high‐efficiency and durable pH‐universal Ru‐based HER electrocatalysts.
Nucleic Acids Enabled‐Interfacial Engineering for Biomarker Sensing with Distance Constraint Effects
Authors: Wang Lu , Tang Shuqi , Li Lin , Jin Kaifei , Xie Xiyue , Chen Yuhua , Cai Kaiyong , Zhang Jixi
Published: January 2023

Controlling the distance of molecular recognition and signal transduction at the nano–bio interface plays a vital role in sensing molecular interactions, which significantly impacts how a biomarker sensor performs in terms of sensitivity, specificity, detection threshold, and response time. However, conventional biosensing interfaces without the design of distance constraint show limited molecular interactions, hindering target accessibility and mass transport. Nuclei acid‐enabled engineering of biosensing interfaces facilitates highly regulated orientation and programmable density control of biomolecules, providing an effective strategy to improve the performance of biosensing platforms for early diagnosis of diseases and regulation of cellular activities. This review summarizes the recent advances in nucleic acid‐based engineering of biosensing interfaces from a unique perspective of distance constraint effects. The roles of structural nucleic acids in delicately programmed assemblies, functional nucleic acids in molecular recognition, and sensor reactions at well‐controlled distances are highlighted. Then applications of advanced biosensing platforms with the effect of distance constraint are introduced. Finally, the current challenges and future directions for developing such biosensors that can compete effectively to meet the requirements of point‐of‐care testing are also discussed.
Diagnostic features of low‐ and high‐grade mucinous neoplasms in pancreatic cyst FNA cytology
Authors: Sigel Carlie , Wei Xiao‐Jun , Agaram Narasimhan , Sigel Keith , Raza Roshan , Andrade Rebecca , Rao Rema , Shah Pari , Soares Kevin , Goyal Abha
Published: January 2023

Background

Pancreatic cyst cytology evaluates for neoplastic mucin and epithelial grade. This study describes cytological features of low‐ and high‐grade mucinous neoplasms (MNs) using gastrointestinal contaminants for comparison.

Methods

Histologically confirmed pancreatic cystic neoplasms were reviewed by a panel of cytopathologists to identify which, among 26 selected cytologic features, correlate significantly with low‐ and high‐grade MN. A test for greater than or equal to four of eight high‐grade features (three‐dimensional architecture, high nuclear:cytoplasmic ratio, moderate nuclear membrane abnormalities, loss of nuclear polarity, hyperchromasia, >4:1 nuclear size variation in one cluster, karyorrhexis, and necrosis) was assessed for identifying a high‐grade neoplasms. Additional characteristics of the cohort such as cyst fluid carcinoembryonic antigen results, molecular testing, Papanicolaou Society of Cytopathology classification, and select high‐risk clinical features are described.

Results

Endoscopic ultrasound fine‐needle aspirations from 134 MN and 17 serous cystadenomas containing gastrointestinal contaminants were included. The MN consisted of 112 (84%) intraductal papillary MNs (low‐grade = 69, 62%; high‐grade = 24, 21%; and invasive = 19, 17%) and mucinous cystic neoplasms (low‐grade = 20, 90%; high‐grade = 2, 10%). Half had greater than five clusters of epithelium for analysis. Compared with gastrointestinal contaminants, mucin from MN was thick and colloid‐like (40% vs. 6%, p < .01), covered >20% of the smear area (32% vs. none, p < .01), and contained histiocytes (46% vs. 18%, p = .04). Greater than or equal to four of eight select high‐grade features was present in 36% of high‐grade MN with sensitivity 37% and 98% specificity.

Conclusion

Colloid‐like features, >20% of smear, and histiocytes correlated with MN. Testing for greater than or equal to four high‐grade features had low sensitivity and high specificity for high‐grade MN.
Sigma Delta Quantization for Images
Authors: Lyu He , Wang Rongrong
Published: January 2023

In signal quantization, it is well‐known that introducing adaptivity to quantization schemes can improve their stability and accuracy in quantizing bandlimited signals. However, adaptive quantization has only been designed for one‐dimensional signals. The contribution of this paper is two‐fold: (i) we propose the first family of two‐dimensional adaptive quantization schemes that maintain the same mathematical and practical merits as their one‐dimensional counterparts, and (ii) we show that both the traditional 1‐dimensional and the new 2‐dimensional quantization schemes can effectively quantize signals with jump discontinuities, which immediately enable the usage of adaptive quantization on images. Under mild conditions, we show that by using adaptivity, the proposed method is able to reduce the quantization error of images from the presently best to the much smaller , where s is the number of jump discontinuities in the image and P () is the total number of samples. This ‐fold error reduction is achieved via applying a total variation norm regularized decoder, whose formulation is inspired by the mathematical super‐resolution theory in the field of compressed sensing. Compared to the super‐resolution setting, our error reduction is achieved without requiring adjacent spikes/discontinuities to be well‐separated, which ensures its broad scope of application.

We numerically demonstrate the efficacy of the new scheme on medical and natural images. We observe that for images with small pixel intensity values, the new method can significantly increase image quality over the state‐of‐the‐art method. © 2022 Wiley Periodicals, Inc.
Empirical Hydrogen Bonding Donor (HBD) Parameters of Organic Solvents Using Solvatochromic Probes – A Critical Evaluation
Authors: Spange Stefan , Weiß Nadine
Published: January 2023

The solvatochromicity of established solvatochromic UV/Vis probes, which appear to be sensitive to the so‐called hydrogen bond donor (HBD) property of the solvent, is analysed using the hydroxyl group density of alcoholic solventsDHBDas a physical parameter in comparison to the pKa, the chemical benchmark for acidity. Reichardt's dyeB30, KosowersZ‐indicator 1‐ethyl‐4‐(methoxycarbonyl) pyridinium iodide (K), Kamlet‐Tafts α, DragosSparameter, CatalansSAscale, thecis‐dicyano‐bis (1,10‐phenanthroline) iron II complex (Schilt's Ferrocyphen dye,Fe) and Gutmann‘s acceptor number (AN) have been investigated. The observed dependencies of the empirical polarity parameters as a function ofDHBDfor several alcoholic solvent families requires a ompletely new physicochemical understanding of these established HBD parameters. Only theANscale (orFe) is able to bridge the gap between global polarity and acidity, provided the values are interpreted correctly and applied accordingly.
The global depth range of marine fishes and their genetic coverage for environmental DNA metabarcoding
Authors: Duhamet Agnès , Albouy Camille , Marques Virginie , Manel Stephanie , Mouillot David
Published: January 2023

The bathymetric and geographical distribution of marine species represent a key information in biodiversity conservation. Yet, deep‐sea ecosystems are among the least explored on Earth and are increasingly impacted by human activities. Environmental DNA (eDNA) metabarcoding has emerged as a promising method to study fish biodiversity but applications to the deep‐sea are still scarce. A major limitation in the application of eDNA metabarcoding is the incompleteness of species sequences available in public genetic databases which reduces the extent of detected species. This incompleteness by depth is still unknown. Here, we built the global bathymetric and geographical distribution of 10,826 actinopterygian and 960 chondrichthyan fish species. We assessed their genetic coverage by depth and by ocean for three main metabarcoding markers used in the literature: teleo and MiFish‐U/E. We also estimated the number of primer mismatches per species amplified by in silico polymerase chain reaction which influence the probability of species detection. Actinopterygians show a stronger decrease in species richness with depth than Chondrichthyans. These richness gradients are accompanied by a continuous species turnover between depths. Fish species coverage with the MiFish‐U/E markers is higher than with teleo while threatened species are more sequenced than the others. “Deep‐endemic” species, those not ascending to the shallow depth layer, are less sequenced than not threatened species. The number of primer mismatches is not higher for deep‐sea species than for shallower ones. eDNA metabarcoding is promising for species detection in the deep‐sea to better account for the 3‐dimensional structure of the ocean in marine biodiversity monitoring and conservation. However, we argue that sequencing efforts on “deep‐endemic” species are needed.
Forecasting housing investment
Authors: Cañizares Martínez Carlos , de Bondt Gabe J. , Gieseck Arne
Published: January 2023

This study applies a model averaging approach to conditionally forecast housing investment in the largest Euro area countries and the Euro area. To account for substantial modeling uncertainty, it estimates a large and diverse number of vector error correction models using a wide set of long‐ and short‐run determinants and applies subset selection based on in‐sample and out‐of‐sample criteria. First, a pseudo out‐of‐sample forecast exercise shows that our model averaging approach consistently beats a battery of distinguished benchmark models, including BVARs, FAVARs, LASSO, and Ridge regressions. This evidences that model averaging provides more accurate forecasts also in the case of housing investment. Second, we find remarkable cross‐country heterogeneity in the drivers of housing investment. Overall, these findings guide forecasters and modelers on improving housing investment models and policymakers on implementing country‐specific housing market policies.
Expression of MSTN/Smad signaling pathway genes and its association with meat quality in Tibetan sheep (Ovis aries)
Authors: He Na , Lang Xia , Wang Cailian , Lv Cailing , Li Mingming , Sun Ruizhe , Zhang Junxia
Published: January 2023

Tibetan sheep is a unique breed living in Qinghai‐Tibet Plateau. Since MSTN/Smad signaling pathway plays a critical role in the regulation of muscle development, we aimed to study the mutton quality, mRNA expression of main transduction genes in the MSTN/Smad signaling pathway, and the effects of those genes on the mutton quality of Tibetan sheep in this study. Six‐month‐old Qinghai‐Tibetan sheep were selected, slaughtered, and their Longissimus lumborum, semitendinosus muscle, arm triceps, and quadriceps femoris muscle were collected. The mutton quality was evaluated, and gene expression and their association with the mutton quality were analyzed using RT‐qPCR. The results showed that the indexes of mutton quality were not significantly different between ewes and rams (p > .05) except for Warner–Bratzler shear force (WBSF) (p < .05). A total of 21 different fatty acids were detected in the muscles of Tibetan sheep, including nine types of SFA, four types of MUFA, and eight types of PUFA. The main transduction genes of the MSTN/Smad signaling pathway were found to be widely expressed in muscle tissues, but no significant differences were observed (p > .05). The correlation analysis of the main genes and mutton quality showed that MSTN was significantly correlated with redness and cooking time; Smad2, Smad3, Smad4, and TGFβRI had significant positive correlations with marbling in arm triceps; Smad3 and TGFβRII had strong negative correlations with pH24 h in Longissimus lumborum; Smad2 was negatively correlated with drip loss in Longissimus lumborum. In short, the expression level of MSTN in muscles was positively correlated with Smad2, Smad3, and Smad4 genes and negatively correlated with TGFβRII genes. Thus, the results of this study provide a theoretical basis for the regulation mechanism of the MSTN/Smad pathway on mutton quality.
Looking up and fitting in: Team leaders' and members' behaviors and attitudes toward the environment in an MNC
Authors: Baldassari Paul , Eberhard Sophie , Jiang Yuan , Muller‐Camen Michael , Obereder Lisa , Schiffinger Michael , Thiele Raik
Published: January 2023

As an emerging topic in human resource management (HRM) research, organizational citizenship behavior for the environment (OCBE) and workgroup green advocacy (WGGA) have been studied as a proxy of the environmental performance of organizations as well as a potential way for companies to assess the impact of their environmental strategies and initiatives. Viewing OCBE and WGGA as green‐focused knowledge, skills, abilities, and other characteristics and building on leader‐member exchange theory, we examined the effects of leaders' OCBE and WGGA, person‐supervisor fit (PSF), and person‐group fit (PGF) as well as their potential interactions on members' OCBE and WGGA. To minimize the potential impact of different company strategies, the study was conducted in one MNC using a sample of 269 members from 64 teams. The results revealed that PSF and especially PGF were associated with members' OCBE and WGGA, but leaders' OCBE was a stronger predictor of members' OCBE and WGGA than leaders' WGGA. Contrary to our prediction, no moderating effect of PSF or PGF was found for the associations between leaders' and members' WGGA and OCBE. Together, these findings shed light on the differential trickle‐down effects of leaders' perceptions and behaviors in the context of environmental management. As for the implications for HRM practitioners, our findings suggest companies may focus on leaders' OCBE and WGGA as well as on PSF and PGF independently as the means to shaping team members' OCBE and WGGA to support environmental strategies.