bluuebunny/crossref_metadata_2025 huggingface dataset:
Preoperative Evaluation of 3D-MRI on the Depth of Myometrial Invasion of Endometrial Carcinoma: 3D Study of Endometrial Carcinoma
Authors: Fu Jiaxin , Cui Yuhui , Xu Liqun , Shen Ping , Liu Xilong , Chen Chunlin , Liu Ping
Published: September 2022

Background: To evaluate the preoperative diagnostic efficacy of 3D-MRI for the depth of myometrial invasion of endometrial carcinoma. Methods: A total of 116 patients with endometrial carcinoma who had undergone pelvic MRI before surgery were included. Mimics 21.0 (Materialize Co., Belgium) software was used to reconstruct three-dimensional MRI models (3D-MRI). The tumor volume and surface area, uterine volume and surface area were measured, and the tumor volume ratio was calculated. TVR (Tumor Volume Ratio) = tumor volume/uterine volume, TAR (Tumor Area Ratio) = tumor surface area/uterine surface area. Postoperative pathology was used as the gold standard to compare the accuracy, sensitivity, specificity, negative predictive value, and positive predictive value of conventional MRI and 3D-MRI in preoperative assessment of endometrial carcinoma myometrial invasion. Results: The accuracy and specificity of 3D-MRI in the diagnosis of deep myometrial invasion were better than conventional MRI (p < 0.05). There was no statistically significant difference in tumor volume or surface area between stage IA and stage IB (p > 0.05), while TVR and TAR showed significant statistical differences (8.05 ± 0.66 vs. 19.12 ± 3.20, p < 0.01; 21.38 ± 1.04 vs. 35.15 ± 3.42, p < 0.01). Further analysis, the area under the ROC curve of TVR is 0.738, p < 0.01, and the best cut-off value is 13.59%; the area under the ROC curve of TAR is 0.770, p < 0.01, and the best cut-off value is 27.41%. Conclusions: Preoperative 3D-MRI can effectively assess the myometrial invasion of endometrial carcinoma.
Characterization of the Sphingolipidome of the Peri-Infarct Tissue during Hemorrhagic Transformation in a Mouse Model of Cerebral Ischemia
Authors: Lucaciu Alexandra , Trautmann Sandra , Thomas Dominique , Lachner Karsten , Brunkhorst Robert , Subburayalu Julien
Published: September 2022

Background: Cardiovascular diseases like stroke cause changes to sphingolipid mediators like sphingosine 1-phosphate (S1P) or its ceramide analogs, which bear the potential to either alleviate or exacerbate the neurological damage. Therefore, the precise identification of alterations within the sphingolipidome during ischemic stroke (IS) and hemorrhagic transformation (HT) harbors a putative therapeutic potential to orchestrate local and systemic immunomodulatory processes. Due to the scarcity of research in this field, we aimed to characterize the sphingolipidome in IS and HT. Methods: C57BL/6 mice underwent middle cerebral artery occlusion (MCAO) and specimens of the peri-infarct tissue were taken for sphingolipid profiling. Results: Ischemic stroke resulted in reduced S1P whilst ceramides were elevated six hours post ischemia onset. However, these differences were nearly revoked at 24 hours post ischemia onset. Moreover, the topmost S1P and ceramide levels were linked to the presence of HT after MCAO. In this study we show the characterization of the sphingolipidomic landscape of the peri-infarct tissue after ischemic stroke and HT. Especially, highest values of S1P, C 18 lactosylceramide, C 18 glucosylceramide, and C 24:1 ceramide were nearly entirely expressed by mice with HT. Conclusions: Our results warrant further investigations into the immunomodulatory consequences of altered sphingolipid species for the development of HT after IS.
Comparison of Short-Term DAPT and Long-Term DAPT on the Prognosis of PCI Patients: A Meta-Analysis of Randomized Controlled Trials
Authors: Yang Jiaxin , Ding Yaodong , Wang Rui , Wang Kexin , Liu Xiaoli , Shen Hua , Sun Yan , Ge Hailong , Fang Zhe
Published: September 2022

Background: Dual antiplatelet therapy (DAPT) is the primary medication for patients after percutaneous coronary intervention (PCI). However, the best DAPT duration is still controversial. This systematic review and meta-analysis aims to assess the safety and effectiveness of short-term (3–6 months) DAPT compared to long-term (12 months) DAPT. Methods: We searched PubMed, Embase, Cochrane Library, and Web of Science systematically for all the randomized controlled trials (RCTs) which compared the different strategies for DAPT in patients undergoing PCI within ten years prior to January 2021. Major bleeding and any bleeding were identified as the safe endpoints. All causes of death, cardiac death, myocardial infarction, definite/probable stent thrombosis, target vessel revascularization, and stroke were identified as the efficacy endpoints. The hazard ratio (HR) and 95% confidence interval (CI) in each study were abstracted. Results: Overall, 11 trials and 24,242 patients were included in this meta-analysis with 15-month median follow-up time. Short-term DAPT was related to reduced risks of major bleeding (HR 0.65, 95% CI 0.48–0.89) and any bleeding (HR 0.64, 95% CI 0.53–0.79). No obvious differences in any of the other endpoints were observed. In acute coronary syndrome (ACS) patients with drug-eluting stents (DES), short-term compared with long-term DAPT was related to a decreased risk of major bleeding (HR 0.57, 95% CI 0.37–0.87) without significant increasing in the risks of any bleeding and ischemic endpoints. Furthermore, short-term DAPT followed by P2Y12 receptor inhibitor monotherapy appreciably lowered the risk of major bleeding (HR 0.64, 95% CI 0.42–0.96) and any bleeding (HR 0.58, 95% CI 0.36–0.93). There were no obvious differences concerning death between the different strategies for DAPT. Conclusions: After PCI with DES, short-term DAPT is safer than long-term DAPT, and is not inferior in effectiveness, even in ACS patients. P2Y12 receptor inhibitor monotherapy following short-term DAPT is also related to a decreased risk of bleeding and may be an alternative anti-platelet strategy.
Perception in Krashen's Monitor Utilization and the Learners' English-Speaking Performance
Authors: Caratiquit Lovely Jean C. , Caratiquit Kevin D. , Tamanu Mark John M.
Published: September 2022

Speaking of oral communication has frequently been labeled unfavorable to people because it requires confidence and courage. Thus, it appears to be one of the most challenging learning skills, requiring practice and exposure. This study aimed to investigate the relationship between Senior High School learners' level of performance in spoken discourse and their dominant monitor performance. The study employed a descriptive-correlational research design with 156 respondents selected through stratified random sampling. Recognizing and understanding Senior High School students' monitor performance was expected to motivate teachers to address the root cause of the problem, resulting in more proficient and communicative second language use. The findings disclosed that monitoring performance is crucial in determining the level of performance of learners in spoken discourse. A firm grasp of the English language, including its grammar and vocabulary components, effective discourse management, pronunciation, and interactive communication, are critical components in developing learners' speaking abilities. Additionally, this study revealed that those enrolled in the academic track are proficient at communicating, which explains why most are labeled optimal monitor users. In this regard, they use their information appropriately to strike a balance between self-correction and fluency, ensuring that error repair does not become a barrier to communication. Future recommendations were also discussed in this paper.
Impact of Glutathione Administration on Antioxidant Levels and Ileum Histologic of Growth Phase of Cihateup Duck in Extensively Maintained
Authors: Mushawwir Andi , Suwarno N. , Aritonang H.N.
Published: September 2022

This research has been carried out for a month using eighty three-month-old female Cihateup ducks and has been used to study the influence of glutathione on the endogen antioxidant response and  histological illeum. The separation of glutathione was carried out using the distillation technique. Each experimental group consisted of 20 ducks, each treated with G0 = without glutathione; G1= Administration of glutathione 150 µL/head; G2 = Administration of glutathione 175 µL/head; G3= Administration of glutathione 175 µL/head. Tissue and blood sampling was collected at the end of the study by EDTA tube and a fixative solution, and tissue preparations were made using the Mallory-Asan technique and analyzed using a binocular microscope. Antioxidant levels were measured using a spectrophotometer technique based on the instructions of the Randox Kit. The results showed that glutathione affected (P<0.05) morphometric ileum (villi, Peyeri's plaque and goblet cells) and increased with increasing glutathione level and endogenous antioxidant response. It was concluded that glutathione is able to stimulate protein and lipid anabolism, as well as hormonal signals related to ileal tissue growth and antioxidants.
Differential expression of DCAF1 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: September 2022

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines sporadic ALS using published data (3, 4). We found significant differential expression of DCAF1, encoding DDB1- and CUL4-associated factor 1, in primary motor neurons of patients with ALS. DCAF1 was also differentially expressed in fibroblasts isolated from patients with ALS. DCAF1 transcript was present at significantly lower levels in ALS patient fibroblasts as compared to control, non-diseased fibroblasts. These analyses will begin to define the transcriptional landscape of ALS.
Impact of stress regime change on the permeability of a naturally fractured carbonate buildup (Latemar, The Dolomites, Northern Italy)
Authors: Igbokwe Onyedika Anthony , Timothy Jithender J. , Kumar Ashwani , Yan Xiao , Mueller Mathias , Verdecchia Alessandro , Meschke Günther , Immenhauser Adrian
Published: September 2022

Changing stress regimes control fracture network geometry and influence porosity and permeability in carbonate reservoirs. Using outcrop data analysis and a displacement-based linear elastic finite element method, we investigate the impact of stress-regime change on fracture network permeability. The model is based on fracture networks, specifically fracture sub-structures. The Latemar, predominantly affected by subsidence deformation and Alpine compression, is taken as an outcrop analogue for an isolated (Mesozoic) carbonate buildup with fracture-dominated permeability. We apply a novel strategy involving two compressive boundary loading conditions constrained by the study area's NW-SE and N-S stress directions. Stress-dependent heterogeneous apertures and effective permeability were computed by (i) using the local stress state within the fracture sub-structure and (ii) running a single-phase flow analysis considering the fracture apertures in each fracture sub-structure. Our results show that the impact of the modelled far-field stresses at (i) subsidence deformation from the NW-SE and (ii) Alpine deformation from N-S increased the overall fracture aperture and permeability. In each case, increasing permeability is associated with open fractures parallel to the orientation of the loading stages and with fracture densities. The anisotropy of permeability is increased by the density and connectedness of the fracture network and affected by shear dilation. The two far-field stresses simultaneously acting within the selected fracture sub-structure at a different magnitude and orientation do not necessarily cancel out each other in the mechanical deformation modelling. These stresses affect the overall aperture and permeability distributions and the flow patterns. These effects—potentially ignored in simpler stress-dependent permeability—can result in significant inaccuracies in permeability estimation.
Effortfulness of Visual Working Memory: Gauged by Physical Exertion
Authors: Xie Weizhen , Zhang Weiwei
Published: September 2022

Active maintenance of information in working memory (WM) is an essential but effortful cognitive process. Yet, the effortful nature of WM remains poorly understood. Here, we constructed a model to evaluate how perceived effort of WM is directly compared to that of physical exertion. In Experiment 1, participants freely chose to either remember a certain number of colors in a visual WM task or hold a hand dynamometer to a required percentage of maximal voluntary contraction (%MVC) to obtain a fixed task credit upon successful task competition. We found that participants discounted WM-related effort in the same way as they discounted handgrip-related effort based on a computation of expected choice outcomes (hence utility) associated with different task loads. This rationality in an observer’s prospective choice in Experiment 1 was generalized to retrospective choice in Experiment 2 where participants reported which task was more effortful immediately after they had performed both tasks in a randomized order without any reward or feedback. Experiment 3 further probed this shared mechanism using a dual-task paradigm. As predicted by our model, we found that physical exertion could disrupt the performance in the concurrent WM task, proportional to the iso-effort relationship between WM and physical exertion when task loads were high for both tasks. Collectively, our findings converge on a shared computational principle connecting task load, perceived effort, and choice utility across physical and cognitive domains.
Reliability and Validity of the Japanese Version of the Camouflaging Autistic Traits Questionnaire
Authors: Hongo Minako , Oshima Fumiyo , Guan Siqing , Takahashi Toru , Nitta Yusuke , Seto Mikuko , Hull Laura , Mandy William , Ohtani Toshiyuki , Tamura Masaki , Shimizu Eiji
Published: September 2022

This study investigated the factor structure and determined the reliability and validity of the Camouflaging Autistic Traits Questionnaire–Japanese version (CAT-Q-J) among 204 autistic and 410 non-autistic people. Since a confirmatory factor analysis revealed no factor validity of the CAT-Q-J for both autistic and non-autistic adults, an exploratory factor analysis was conducted to ensure the psychometric properties matched those of the original scale as much as possible. The results showed the CAT-Q-J comprised three subscales, a four-item compensation subscale, a five-item masking scale, and a five-item assimilation subscale. The overall CAT-Q-J and all three subscales showed sufficient internal consistency and moderate-to-good and stable test-retest reliability in both the autistic and non-autistic samples. Convergent validity was also supported by the correlations found with measures of autistic traits, well-being, anxiety, and depression. Different from the original CAT-Q, compensation/masking for the autistic sample was not correlated with mental health or autistic traits. The reliability and the validity of the overall CAT-Q-J were confirmed; however, caution should be exercised when interpreting its subscales.
Contested Identity and Prejudice Against Co-ethnic Refugees: Evidence from South Korea
Authors: Kim Jae Yeon , Lee Taeku
Published: September 2022

Although North Korean refugees are co-ethnics and receive extensive government support, many reports have alleged that they are discriminated against in South Korea. We theorize that this outcome is due to the contested status of North Korean refugees’ co-ethnic identity. We test this with embedded list experiments on an approximately nationally representative sample of South Koreans (n = 1,418). We find that (1) South Koreans hold prejudice against North Korean refugees primarily because they believe supporting these refugees would waste government resources; (2) liberals are more likely to disagree with this belief while conservatives are ambivalent, and (3) income predicts this belief better than partisanship or ideology. Scholars have focused on native-refugee conflict cases where ethnic identity is a faultline. However, the South Korean case shows that co-ethnic refugees could be unwelcomed in a host society if political and economic factors make their co-ethnic status contested.
Do jihadist terrorist attacks cause changes in institutional trust? A multi-site natural experiment
Authors: Nägel Christof , Nivette Amy , Czymara Christian S.
Published: September 2022

Results from previous research suggest that terrorist attacks lead to relatively short-term increases in trust in institutions. The explanation for this increase is known as the “rally effect”, whereby individuals respond to crises and threats with more positive support for political leaders and institutions. Even though the number of related natural experiments with survey data is increasing, these studies merely represent case studies of single incidents with limited external validity. In order to advance quasi-experimental research on the effects of terrorist attacks on institutional trust, we propose a new methodological approach by assessing all jihadist terrorist attacks resulting in at least one civilian death in a European country that take place during the fieldwork of the European Social Survey and combine the results of eight unique natural experiments in five different countries using meta-analytic and meta-regression techniques. The results of this “multi-site natural experiment” indicate that support for the rally-hypothesis is mixed at best. While some attacks appear to significantly increase at least some measures of institutional trust (e.g., The Netherlands 2004, France 2015, Israel 2012), others seem to have no effect at all (e.g., Germany 2015, France 2018), or even substantially decrease trust in domestic political institutions (Russia 2012). Summary effects from multilevel meta-analysis are non-significant for any institutional trust outcome. These results are robust to a large number of robustness tests and alternative specifications. In comparison with previous research, it appears that a lot of the European evidence for the rally-hypothesis was based on “outlier” case studies like the Charlie Hebdo attack in France, 2015. Accordingly, our results cast doubt on the unrestricted generalizability of rally effects after terrorist attacks to different geographic, political, social, or historical contexts.
Binge eating and sitting behavior as a risk cluster in obesity among software employees
Authors: Yenuganti Vishnu Vardhan , Sivakumar Rajesh Kannan , Darmisetty Srinivas Rao , P J Sasikumar
Published: September 2022

Introduction: Binge eating disorder (BED) was underdiagnosed, underestimated eating disorder known to be responsible for obesity in both children and adults. Sedentary behavior estimated by measuring the sitting time was one of the major contributing factors in the development of metabolic syndrome in adults. People working in Information Technology (IT) sector possess both of these determinants in a significant capacity and thereby might be at risk for obesity, which in turn can be responsible for various cardio-metabolic events in their life.
Methods: A cross-sectional study was conducted on 513 working adults belonging to the IT sector, using a face-to-face interview with a pre-tested questionnaire along with anthropometric measurements to measure BMI for obesity. Binge-eating disorder screener-7 for adults was adopted to assess the disorder, and the Marshall Sitting Questionnaire was used to evaluate their sitting behavior.
Results: The study found that the prevalence of BED (23%) was higher in unmarried individuals, and moderate BED is significantly associated with higher BMI among them. Conversely, sitting time (Mean=8.83 hours/day) was seen mostly in married adults, and is also associated with higher BMI. As a risk cluster, both BED and sitting time combined had higher odds of resulting in Obesity than existing separately.
Conclusion: Several lifestyle factors such as binge-watching TV, late working hours, higher salaries, etc., have contributed to developing Binge eating disorder and higher sitting time, which pose a significant risk for metabolic disorders like obesity.
Dermoscopy of Psoriasis: A Cross Sectional Study
Authors: Thapa Deeptara Pathak , Adhikari Harihar , Bhandari Sajana
Published: September 2022

Introduction: Dermoscopy is a non-invasive tool that aids in the diagnosis of dermatological diseases.
Objectives: The study aims to evaluate the dermoscopic features of psoriasis in the skin.
Materials and Methods: All patients clinically diagnosed with psoriasis were enrolled in the study. Dermoscopic findings were studied using a handheld pocket dermoscope (Dermlite DL1) with high magnification. Dermoscopic examination used both polarizing and non-polarizing lenses.
Results: The age of the patients ranged from 12 years to 58 years, and the mean age of presentation was 30 years (+/-12.7 years). There were 52% females and 48% males. In dermoscopy, vascular changes were seen in 90%. Vessel arrangement was seen as uniform in 80% of the cases and non-uniform in 20%. Dotted vessels were seen in 88%, glomerular and comma-shaped vessels in 2%. In 94%, white scales were seen, followed by yellow scales in 2% and mixed types in 4%. The background color was red in 68% of cases, pink in 26%, and brownish in 6%. Pigmentary changes were observed in 16%. Follicular changes were observed in 6%. 
Conclusion: The present study analyzed the characteristic of dermoscopic features in psoriasis. Further studies should be conducted, including inflammatory disorders and their correlation with dermoscopic features.
ORGANIZATION PRINCIPES AND FINANCIAL FACTORS OF INVIROMENTAL MANAGEMENT IN MODERN CONDITIONS
Authors: Kоreniuk Petr
Published: September 2022

The field of nature management is an important component of the national economy, because it ensures the implementation of the economic use of natural resources and the preservation of the environment as a factor of socio-economic growth. The essence and content of environmental management consists in obtaining a multiplier profit from nature-reproducing activities based on parity between ecological, economic and social components. In essence, environmental management studies economic methods of managing the natural conditions of human habitat in parity with ecological and social components. At the same time, the limitation of natural resources contributes to a certain extent to the problem of contradiction in the relationship: man - nature - society. It is important to have a triune approach in environmental management, where economy, ecology and social consequences will have parity when solving production problems of human life. It is necessary to find an optimum between the needs of human society and the potential opportunities of the natural environment. It is necessary to take resources from nature not in the amount that is needed to satisfy human needs, but in the amount that it can give without damage to its recovery process. As human society develops, economic-ecological contradictions are intensifying. And at the same time, the role of environmental management as a tool for inhibiting and resolving them is growing. The role of the manager of the natural environment is significant in achieving a multiplier economic and ecological effect. The capital invested in environmental protection measures will definitely give an economic return in the strategic plan: the quality of food products, the health of the population, etc. With the help of the above-mentioned economic methods, the application of economic levers will contribute to the growth of the efficiency of environmental management in the branches of the national economy. In our opinion, at the micro level, it is appropriate to provide for the determination of the need for financial resources for the implementation of measures for the expanded reproduction of natural resource potential, the determination of criteria for the selection of alternative sources of financing environmental programs and projects.
SOCIAL ENTERPRISE AS A FACTOR OF ENSURING THE ECONOMIC SECURITY OF DOMESTIC ENTERPRISES IN THE CONDITIONS OF MODERN CRISES
Authors: Dragun Andriy
Published: September 2022

The article considers the social enterprise as the implementation of a new "social contract". New aspects of the contradiction between the employee and the latest technologies implemented by enterprises are considered. The main elements of the new model of relationships in a modern enterprise are considered in order to develop approaches and ways to eliminate the conflict of interest of employees in a high-tech enterprise. The study is based on the further development of elements of a new model of interaction between workers and modern social enterprises was the principle of taking into account the interests of the enterprise, workers and society as a whole.

The elements of the new model of interaction between workers and modern technologies of social enterprise were: the creation of a new format of work in the period of return after the crisis or work during the external crisis; analysis and identification of new opportunities after the crisis and their implementation in every aspect of daily work, the formation of new business requirements due to the crisis, the implementation of new opportunities, the formation of employee welfare, taking into account the characteristics and benefits of different groups , artificial intelligence in work teams, the use of institutional knowledge to change the role of employees, the creation of new industries, branches, etc .; providing retraining of workers; HR functions in the enterprise, ensuring future dynamic stability. Each element is given a brief description. The domestic experience of realization of corporate social responsibility is resulted.

An aspect of social responsibility such as caring for the health and safety of workers is shown. This aspect is an important factor in the successful operation of the enterprise in times of crisis. It is determined that for domestic enterprises such care for employees can be their health insurance. The approach of effective introduction of voluntary medical insurance of employees of the enterprise at the expense of the employer is resulted.
PARAMETRIC ANALYSIS OF THE BUDGETARY AND ESTIMATED FINANCING OF THE VOCATIONAL AND TECHNICAL EDUCATION INSTITUTION CITY OF KAMIANSKY
Authors: Hanziuk Svitlana , Brezhnieva-Yermolenko Olha
Published: September 2022

In the article analyzes theoretical and practical aspects of financial support of educational institutions in Ukraine. It has been established that since 2014, the state has not been able to ensure the implementation of the amount of funding at the level of 7 percent, as stipulated in the Law of Ukraine "On Education", although in recent years, this indicator has been maintained at a stable level – 6 % of GDP. The state of financing education in Ukraine by components of the education system (preschool, full general secondary, professional (vocational-technical), higher, post-graduate) was considered. The main sources of financial support of institutions of professional (vocational and technical) education in Ukraine have been determined.

A parametric and prospective analysis of the coefficients of the budget-estimated financing of the vocational and technical education institution of the city of Kamiansky was carried out. It was established that during the studied period, budget funding gradually increased; the general structure of financial support is actually stable; the total amount of current expenses increased; there are no capital expenditures, which is due to the deficit of the budget of Ukraine for relevant measures; cash and actual expenses demonstrated the targeted spending of budget funds in accordance with estimated allocations; the projected growth of general fund expenditures for the next year is 15.5%.

A number of promising directions for improving the system of financial support and development of vocational (vocational-technical) education institutions in Ukraine are proposed, including: improvement of the legal framework for vocational (vocational-technical) education in accordance with modern legislation, which will make it possible to clearly distribute powers from management and financing of professional (vocational and technical) education institutions at each level and introduce responsibility for the irrational use of resources; completion of the transfer of vocational (vocational and technical) education institutions from state to communal ownership and transition to financing from regional budgets of vocational (vocational and technical) education institutions located on the territory of cities of regional importance – regional centers; involvement of the private sector of the country's economy in cooperation with the state within the framework of public-private partnership, etc.
PROCEDURES FOR OBTAINING AND EVALUATING AUDIT EVIDENCE
Authors: Budko Oksana , Lola Viktoriia
Published: September 2022

The purpose of the article is to study the process of obtaining audit evidence and methods of their evaluation in the context of the application of International Auditing Standards. The article defines the concept of audit evidence. The main requirements for audit evidence are characterized (acceptability as a measure of the quality of audit evidence; sufficiency as a measure of the amount of audit evidence). The content of the international audit standards, which determine the procedure for collecting audit evidence (IAS 500, IAS 501, IAS 505, IAS 520, IAS 315, IAS 330), is highlighted. The classification of audit evidence is presented (depending on the sources of receipt, on proximity to the real fact, on the method of obtaining audit evidence, on the form of submission, on the purpose of evidence collection, on the degree of accuracy, on the degree of reliability and persuasiveness). The essence of audit procedures used to obtain audit evidence (verification, request, confirmation, recalculation, analytical procedures) is highlighted. Procedures for collecting audit evidence are analyzed on the example of checking the correctness of depreciation (amortization) of fixed assets and its display in accounting. The situations that characterize the correspondence of accounting data with financial reporting data are defined. The characteristics of assessing the quality of audit evidence (sufficiency, reliability, relevance, usefulness) are revealed. The stages of obtaining audit evidence are proposed, which include determining the purpose of obtaining audit evidence, determining the sources of information for obtaining evidence, assessing the risks of material distortion of information, choosing audit procedures, collecting evidence, analyzing the collected evidence, collecting the necessary additional evidence, evaluating the obtained evidence, forming an opinion the auditor based on the received evidence. It was established that the value of each stage of obtaining audit evidence is determined by the sequence of the auditor's actions, the degree of importance of the results obtained at a certain stage of the audit from the point of view of the validity of the general results, the amount of time and labor costs.
“Slavic” or “Germanic Spirit”? Examples of the Ideologisation of Arcades in Research on Architecture in the 19th and 20th centuries
Authors: Gliński Radosław
Published: September 2022

Travelling across present-day Poland, it is only exceptionally possible to come across a specific type of historic urban and rural houses with a ground-level section open on three sides and supported on columns or posts. Yet still in the first half of the 20th century, in some areas of Europe this type of a house was commonly found, and already a century earlier it had intrigued researchers investigating among other things, its origins of development. Within the current borders of Poland, arcaded houses are found in greater concentration in territories that in the past belonged to different political organisms and thus their research was conducted with the adoption of different optics. It is noteworthy that arcades were easily subjected to various more or less conscious manipulations in order to justify their native character, sometimes understood as belonging to particular peoples, regions, nations or even races. The paper provides hypothesis that arcades are a construction element extremely liable to ideologisation. In order to illustrate this problem, the paper presents methods of interpreting the origin of arcades in former East and West Prussia, Silesia, Lesser Poland and Lublin Province in the period from almost the beginning of the 19th century, when researchers started to be interested in this element, until 1939 when Erich Kulke’s book was published, which was the clearest result of arcades’ ideologisation. These interpretations were divided into a few main groups, which made it possible to compare the narratives and to show how the same arguments could lead to different conclusions. Unique issues, characteristic only of particular regions, were also identified. Ultimately, an attempt was made to answer the question of what influenced the liablity of arcades to ideologisation. Since the authors of the research, often architects, promoted the preservation and use of arcades referring to old patterns in new developments, the question was also asked whether such developments actually occurred.
СОВРЕМЕННЫЕ ПОДХОДЫ К УСПЕШНОМУ ЛЕЧЕНИЮ КОЛОРЕКТАЛЬНОГО РАКА
Authors: Дузенко А.А.
Published: September 2022

В статье представлены результаты аналитического обзора распространенности колоректального рака в мире и Украине, рост заболеваемости которым отмечается повсеместно. Проанализированные данные рассматривают основные факторы риска развития этого опасного заболевания и его осложнений. Показаны современные подходы к профилактике венозных тромбоэмболических и геморрагических осложнений при хирургическом лечении больных колоректальным раком. Акцентировано внимание на важности индивидуализированного подхода в предупреждении развития неблагоприятных исходов хирургического лечения больных КРР.
Generation, Classification, and Human-Plant Analogies in the Mid-Eighteenth Century
Authors: Powell Rosalind
Published: September 2022

Focusing on three pseudonymously published mock-scientific treatises on artificial generation from the 1750s, this article considers the roots and purposes of human-plant analogies in the period. The first half establishes how the texts express anxieties about human classification in light of Linnaean botany, treatments of liminal organisms such as the sensitive plant and the polyp, and unresolved theories about the function of the egg and sperm and the nature of the human embryo. The second half addresses the classification of the infant products of the fictional experiments and of the natural philosophers that present them. In the first case, it draws links between the cultivation systems advocated in these texts and the iatromechanical theories of Stephen Hales and George Cheyne. In the second case, it parallels the natural philosophers’ violence and immodesty with Abraham Trembley’s and Henry Baker’s experiments in the artificial reproduction of polyps.
Political Order and Political Decay: From the Industrial Revolution to the Globalization of Democracy. By Francis Fukuyama. Farrar, Straus and Giroux, 2014. ISBN-13: 978- 1374227357. 672 pp. Hard Cover, $ 35.
Authors: Gul Nabiha
Published: September 2022

Modern states and changing nature of political order has always been of interest to historian and political scientists. Scores of volumes are written on the subject matter from various perspectives covering the origin of state system to the fragmentation of political boundaries, development of supranational entities to the global networks of groups, and institution of market system to the implications of transnational corporations. Moreover, the advent of globalization, with the growing interconnectedness of the world in terms of economies and political order, instigated research studies on the eroding political system, state order and rule of law in many countries.  To bring a comprehensive and an interesting account to readers on the history of modern state, Francis Fukuyama has contributed an impressive study in two volumes beginning from , the prehuman times to the globalization of democracy. The two volumes revolve around the argument that functioning and successful liberal democracy combines three essential elements: the state, rule of law and accountability. The book, a cohort of the first volume, is a project that attempted to advance and update Samuel P. Hungtington’s classic, Political Order in Changing Societies, presents a detailed account of evolution of government and political order in different parts of the world. With some success stories, Fukuyama critically evaluates the causes and consequences of “political decay” of modern state system in many regions.
Anthropological profile of long jumpers: Differences between Olympic games finalists
Authors: GRANIĆ Dejan , PAVLOVIC Ratko
Published: September 2022

The study included a sample of 48 male and female Olympic finalists (Beijing, 2008; London, 2012; Rio de Janeiro, 2016) in the long jump discipline. The following primary parameters of anthropological status (Body height, Body mass, Body Mass Index, Age) and Result (secondary parameter) were analyzed. The aim of the study was to determine the differences in the defined parameters of anthropological status (body height, body weight, BMI, and age) between male and female long jump finalists. The basic central and dispersion indicators were calculated on the basis of which a descriptive comparison of the analyzed variables was performed. The significance of the difference between subjects was examined by MANOVA and ANOVA (p<0.05). The results showed statistically significant differences in mean values of body height in men where the jumpers in Beijing (180,25cm) were lower than the jumpers in London (186.88cm) for level (p<0.05). There were significant differences in height among women, the female athletes in Beijing (175.50cm) were more than the female athletes from Rio (Rio, 169cm), for level (p<0.05). Numerical differences were also recorded for other parameters, but the expected statistical significance was not achievable. It has been shown that anthropometric parameters are relative and not primary. Preference is given to the motor and functional parameters of jumpers.
Cadeia produtiva da piscicultura: um olhar para a evolução da tilapicultura no Brasil
Authors: Carneiro Cleiton Jardel , Luís Brum Argemiro , José Thesing Nelson , Ariel Prochnow Darlan
Published: September 2022

O presente artigo busca a compreensão da cadeia produtiva da piscicultura brasileira, de forma especial, a produção e a comercialização da tilápia, tendo presente o resultado das pesquisas que apontam um crescimento gradativo durante os últimos anos. Assim, busca-se identificar os fatores que passam a influenciar na produção e comercialização da tilápia. O processo de alimentação com cereais, a conquista do mercado interno e externo, atual e futuro, da cadeia produtiva. Para responder as inquietações do estudo, a investigação faz uso da pesquisa qualitativa, descritiva, documental, bem como, para sustentar o rigor e a cientificidade. Os achados do estudo permitem afirmar que a cadeia produtiva está conquistando avanços significativos, tanto no campo científico-tecnológico da produção, quanto na conquista de mercado, tanto nacional como internacional. No entanto, enfrenta alguns desafios, tais como a necessidade da redução dos custos de produção, em função do limitado processo de recuperação econômica do país, bem como, a ampliação do mercado externo. A presença de políticas públicas para conquistar novos avanços científicos e tecnológicos, nos processos produtivos, além da implementação de novas legislações, que contribuem no desenvolvimento sustentável da piscicultura no país
A Review on Cervical Dysplasia: Etiology, Risk Factors, Diagnostic Biomarkers and Possible Nutritional Association
Authors: Dasgupta Shirin
Published: September 2022

Objectives: Cervical dysplasia which is the precursor or premalignant form of cervical cancer is prolonged; hence its diagnosis is essential for the early detection and inhibiting the development of cervical cancer. This review briefs the extensive studies conducted globally to gain knowledge about the development of cervical dysplasia along with the risk factors associated, role of human papilloma virus (HPV), potential diagnostic biomarkers and association with various micronutrient levels. Materials and method: All these data were collected through extensive literature review. Result: Based on the review, it can be stated that HPV virus (HPV 16 most commonly) is the most important etiological agent for the process of cervical carcinogenesis. However, HPV infection solely does not cause cervical cancer. There are various factors which act synergistically to develop cervical dysplasia and cancer. Smoking was found to be an important independent risk factor. There are studies which showed conflicting results regarding oral contraceptive intake association with cervical dysplasia. There are quite a few biomarkers like HPV DNA, p16INK4a, telomerase, and microRNA expression which have been identified as effective in diagnosing cervical dysplasia. Chromosome 3q mutation has been reported to be present in early dysplastic lesions; hence, it can be used in screening early lesions. Various micronutrient studies highlighted the facts that high plasma concentrations of several carotenoids and Vitamin C are inversely proportional to the degree of cervical dysplasia. Low red cell folate levels n plasma increases the risk of cervical dysplasia association. Low dietary intake of Vitamin A is also associated with increased risk of cervical dysplasia. Conclusion: Finally, it can be stated that more extensive studies relating to nutritional and serum markers level need to be conducted with larger cohorts so that an appropriate nutrition plan can be implemented for these patients.
Impact of COVID-19 Pandemic on Medical Practices
Authors: Kumar Balbir , Garg Rakesh , Sirohyia Prashant , Ratre Brajesh Kumar , Singh Ram
Published: September 2022

The COVID-19 pandemic has affected human life in all spheres. However, the medical and health practices seen changed a lot since the arrival of this pandemic. This article describes the positive and negative impact of covid in the medical field. The integration of telehealth needs to be emphasized and positive changes like hand hygiene, wearing a mask, and appropriate social distancing and online interactive learning may be useful in health care practices. Although, the negative effects of the pandemic like ignoring the patients with other comorbidity and deteriorating mental health of HCW must be kept in mind and should be properly addressed.
Sustain Renewable Energy – Lessons for Bangladesh from an Interprofessional Study Conducted in West Michigan, USA
Authors: Molla Azizur , Locher Alexandra , Bacon-Baguley Theresa , Mandale Sonal
Published: September 2022

Objective: Between 1999–2018, the Global Climate Risk Index placed Bangladesh in the top 10 countries most affected from extreme weather events associated with climate change. Implementation of alternative energy may minimize climate change in vulnerable countries. Our objectives were to characterize public knowledge and perceptions of costs and benefits of renewable energy in west Michigan, USA, and recommend areas in which policy discussions on renewable energy should focus. Method: Via email and postal service, we distributed a survey to 1,000 randomly-selected university employees, and 1,000 residents of primarily Ottawa and Kent counties in west Michigan (Grand Valley State University Institutional Review Board #20-118-H). Result: A total of 313 respondents completed the survey, including 170 university employees and 122 county residents. Results suggest that 12.5% of people older than age 60, and people with no college degree use alternative energy sources more than other age classes or those with higher education. Females (p = 0.0636) and people who have lived in their homes for 10–15 years (p = 0.0802) perceived renewable energy as less costly than other sources. Although females perceived less knowledge than males (p = 0.0001), there were no differences in perceived knowledge level among respondents of various ages, education levels, careers, salary, or whether they owned a home. Respondents aged 40–49 and 60–69 also perceived lower pollution from renewable energy than other age groups (p = 0.0393 and p = 0.0779, respectively). Conclusion: With a broader, more diverse population in future work, we anticipate more variability in responses, but similar trends. The prospect of implementing renewal energy is positive and suggests that policy makers should supply incentives, promote education, and invest resources for effective implementation. The Bangladesh government can support studies to understand peoples’ perception of alternative energy sources and explore socially suitable interventions to address climate change.
An Overview of Bangladesh Health Systems Financing
Authors: Ali Molla Azaher
Published: September 2022

Health financing is fundamental to the ability of health systems to maintain and improve human welfare. Bangladesh has a mixed health system both in financing and in delivery of services. Despite a significant economic improvement, health systems financing does not meet the greater needs of the population. Total expenditure on health as a percentage of GDP was 3.4% in 2012 and 2.37% in 2016.
Nursing Education Leader’s Competencies: A Narrative Review
Authors: Alyateem Sami , Houriah Ali
Published: September 2022

This study aimed to shed light on general core competencies among nursing education leaders. Although these competencies have been identified by international organizations such as the World Health Organization (WHO) and National League for Nursing (NLN), the rapidly changing healthcare environment means they should be reviewed regularly. In addition, specific aspects of nursing education leaders’ competencies in different fields (e.g., academic and clinical education) should be highlighted to ensure consistency in nursing education outcomes.This study focused on nursing educators’ competencies. The results may support efforts to improve their competence and inform development of a framework for their scope-related functions. In turn, this may provide a clear guide for their professional development.For nursing students, this study may contribute to improving nursing entry competencies and ensuring students are more ready for practice when they graduate and begin their professional career. Through such contributions, this study may also lead to improved quality of care for patients.