bluuebunny/crossref_metadata_2025 huggingface dataset:
Penerimaan diri dalam keterbatasan fisik: Tinjauan Bimbingan rohani Islam pada Pasien Stroke
Authors: Sabila Dwi Rahayu  , Lina Raikhan Fadila
Published: March 2024

Self-acceptance is an important process for facing physical limitations, especially for stroke patients. Islamic spiritual guidance can be a significant source of support in helping stroke patients achieve greater self-acceptance. This study conducted a review of existing literature to understand the role and effectiveness of Islamic spiritual guidance in helping stroke patients accept and overcome their physical limitations. The literature review research method was used in collecting and analyzing relevant studies. Meanwhile, the nature of this research is descriptive analysis, which involves systematically and orderly analyzing the data that has been obtained. The results show that Islamic spiritual guidance can provide emotional, spiritual, and psychological support to stroke patients, which in turn helps stroke patients accept themselves and face physical limitations. stroke patients better. This article provides insight into the importance of Islamic spiritual guidance as a comprehensive approach to caring for stroke patients. Islamic spiritual guidance can play an important role in helping stroke patients increase self-acceptance. By understanding destiny, overcoming guilt, and strengthening the relationship with God, patients can achieve greater self-acceptance and face change with a more positive attitude.
Penerimaan diri merupakan proses penting dalam menghadapi keterbatasan fisik, terutama bagi pasien stroke. Bimbingan rohani Islam dapat menjadi sumber dukungan yang berarti dalam membantu pasien stroke mencapai penerimaan diri yang lebih baik. Penelitian ini melakukan tinjauan terhadap literatur yang ada untuk memahami peran dan efektivitas bimbingan rohani Islam dalam membantu pasien stroke dalam menerima dan mengatasi keterbatasan fisik pasien stroke. Metode penelitian literatur review digunakan dalam mengumpulkan dan menganalisis studi yang relevan. Sedangkan sifat dari penelitian ini adalah analisis deskriptif dengan mengurai secara sistematis dan teratur data yang telah diperoleh Hasilnya menunjukkan bahwa bimbingan rohani Islam dapat memberikan dukungan emosional, spiritual, dan psikologis kepada pasien stroke, yang pada gilirannya membantu pasien stroke dalam menerima diri dan menghadapi keterbatasan fisik pasien stroke dengan lebih baik. Tulisan ini memberikan wawasan tentang pentingnya bimbingan rohani Islam sebagai pendekatan yang komprehensif dalam merawat pasien stroke. Bimbingan rohani Islam dapat memainkan peran penting dalam membantu pasien meningkatkan penerimaan diri pasien stroke. Dengan memahami takdir, mengatasi rasa bersalah, dan memperkuat hubungan dengan Allah, pasien dapat mencapai penerimaan diri yang lebih baik dan menghadapi perubahan dengan sikap yang lebih positif
Optimalisasi Penghimpunan Dana Zakat dalam Mencapai Target di LAZISMU Banyumas
Authors: Alwi Rokhman Saifulloh
Published: March 2024

Zakat fund collection is one of the main activities of zakat management, every activity in zakat management is aimed at achieving the goal of zakat, namely to improve the people's economy by managing zakat funds that are oriented towards improving the economic conditions of mustahik, so collecting zakat funds must be carried out optimally. To be able to carry out optimal collection, a collection strategy and mechanism is needed. LAZISMU Banyumas implements a strategy and mechanism for collecting zakat funds. The results of collecting zakat at LAZISMU Banyumas are also quite good, and LAZISMU Banyumas has received many national level awards, one of which is  the LAZISMU Award in 2021 to become the best financial amil. The purpose of this research is to find out the mechanism for collecting zakat funds at LAZISMU Banyumas and to find out the strategy of LAZISMU Banyumas in achieving the target of collecting zakat funds. This is  qualitative field research. Data collection techniques include observation, interviews, and documentation. The data analysis techniques used are data reduction, data presentation, and conclusion. Based on the results of this study, it can be concluded that optimizing the collection of zakat funds to achieve targets is carried out by LAZISMU Banyumas, namely by implementing predetermined fundraising strategies such as outreach, direct mail, direct payments to offices, pick up donations, zakat counters, banking channels, QRIS, establishment service offices, online fundraising, and maintenance. The mechanism for collecting zakat funds implemented by LAZISMU Banyumas is by sending socialization notification letters to prospective muzakki, carrying out socialization, and recording the identity of prospective muzakki. LAZISMU Banyumas provides several zakat payment mechanisms. The first is the mechanism for collecting zakat directly at the office, collecting zakat through transfers, and collecting zakat through the pickup and delivery of donations
SUSTAINABLE GREEN ANALYTICAL CHEMISTRY: SPECTROPHOTOMETRIC METHOD DEVELOPMENT OF DAPAGLIFLOZIN AND OMEPRAZOLE BY USING ECO-FRIENDLY SOLVENT
Authors:   Department of Post Graduate in Pharmaceutical Quality Assurance, SVPM’S College of Pharmacy, Malegaon (BKII) Baramati, Pune, Maharashtra, India 413115, JADHAV SAKSHI A. , BHILARE NIKITA A. ,   Department of Post Graduate in Pharmaceutical Quality Assurance, SVPM’S College of Pharmacy, Malegaon (BKII) Baramati, Pune, Maharashtra, India 413115, CHANDANSHIVE B. ,   Department of Post Graduate in Pharmaceutical Quality Assurance, SVPM’S College of Pharmacy, Malegaon (BKII) Baramati, Pune, Maharashtra, India 413115, DYADE GURAPPA K. ,   Department of Post Graduate in Pharmaceutical Quality Assurance, SVPM’S College of Pharmacy, Malegaon (BKII) Baramati, Pune, Maharashtra, India 413115, LUNKAD AMIT S. ,   Department of Pharmaceutical Chemistry, SitabaiThite College of Pharmacy, Shirur, Pune, Maharashtra, India 412210
Published: March 2024

The present research’s aim was to develop analytical method utilizing ecologically suitable solvent which enhances solubility of analyte, sensitivity of the method etc. An analytical method was developed for the estimation of dapagliflozin (DGZ) and omeprazole (OPZ) by using aqueous 0.1 N HCl on the UV-VIS spectrophotometer. Wavelengths 223 nm and 282.5 nm were set to measure absorbance of DGZ and OPZ respectively. The results of different spectral characteristic techniques were examined to select the parameters and the design was validated against the ICH Q 2 R1 regulatory guidelines. The linearity of the drug was determined at a concentration of 1 to 50μg/ml and 1 to 32μg/ml for DGZ and OPZ respectively. The accuracy was found within acceptable limit with standard deviation 1.1874 to 6.4984 for DGZ and 0.1401 to 0.9843 for OPZ; and the assay study data was found 99.77 % for DGZ and 97.92 % for OPZ. The stability study of the method was performed out by minute variation in the wavelength, scan speed. The developed method is rigid, robust and efficient for the estimation of DGZ and OPZ from their respective dosage form. The effort was made to develop green or eco-friendly analytical method utilizing hydrotropic solvent for water insoluble drug dapagliflozin and omeprazole. KEYWORDS: Green method, Dapagliflozin, Omeprazole, analytical method, eco-friendly solvent, UV spectroscopy.
The Implementation of Tolerance Values in Grade V Elementary School Students
Authors: Ramadani Nuresi , Pratiwo Yuda , Hendriana Evinna Cinda , Mertika Mertika
Published: March 2024

The objectives to be achieved in this study are to determine: a description of the implementation and the supporting and inhibiting factors in the implementation of tolerance values in the fifth-grade students of SDN 7 Singkawang. This type of research is a type of descriptive qualitative research. Data collection techniques were carried out by observation and interviews, while additional data was in the documentation. This study uses data analysis techniques with three paths, namely data reduction, data presentation, and verification. The results of this study indicate that the implementation of tolerance values in fifth-grade students of SDN 7 Singkawang is in the form of being able to respect the opinions of others, being able to accept gracefully if they are wrong, being able to express their opinions politely, and not offending others both in words and actions. Factors that influence the implementation of tolerance values in fifth-grade students at SDN 7 Singkawang are categorized into two factors, namely supporting factors and inhibiting factors. Supporting factors are self-awareness, a sense of nationalism in diversity, parents support, teacher encouragement, and support from schools. The inhibiting factor is a closed personality.
Urgensi Penelitian Tindakan Kelas (PTK) untuk Meningkatkan Kualitas Pembelajaran pada Masa New Normal
Authors: Diana Risma Firda , Sufia Rohana , Ixfina Ficky Dewi
Published: March 2024

The various kinds of obstacles occur in the learning process during the pandemic. One approach to solving learning problems is Classroom Action Research (CAR). The purpose of this study is to describe the urgency of CAR to improve the quality of learning in the new normal. This research method is descriptive and qualitative. The research subjects were active elementary teachers in East Java. The data collection instrument in this study was a questionnaire distributed online. The results of the study showed that 100% of the participating teachers thought that CAR was important to implement. This is because they benefit from the implementation of CAR, namely improving the quality of learning. However, the implementation of CAR during the pandemic experienced various obstacles including limited internet connection and face-to-face time. This is a challenge for teachers to continue to carry out CAR with the blended learning method to overcome learning problems that occur during the new normal period.Â
Comparison of Auditory Intellectually Repetition Approach and Student Teams Achievement Division Approach to Mathematics Learning Outcomes of Elementary School Students
Authors: Abdul Karim , Rukli Rukli , Sukmawati Sukmawati
Published: March 2024

This study compares the Auditory Intellectually Repetition approach and the Student Teams Achievement Division approach to elementary school mathematics learning outcomes. This type of research is quantitative research. The research design used is the Pretest Posttest Control Group Design. The population in this study were fifth-grade students in Mappkasunggu District, and the samples of this research were fifth-grade students of public elementary school No. 106 Inpres Takalar I and fifth-grade students of state elementary school no. 23 Center Takalar I. The data collection technique used was multiple choice questions. The research results based on descriptive analysis showed that the average value of mathematics learning outcomes with the AIR learning approach reached 75.33, and the Student Teams Achievement Division approach reached 60.67. At the same time, the results of the inferential analysis show that the Auditory Intellectually Repetition approach has a more significant effect than the Student Teams Achievement Division approach on student mathematics learning outcomes. The sig value obtained based on the multivariate test table in the Manova test is smaller than 0.05.
Diego Rivera, un personaje público entre el reconocimiento y la polémica
Authors:   , Patiño Navarro María Norma
Published: March 2024

La propuesta principal de la tesis es demostrar que las estrategias de reconocimiento que se plantean y se practican en el siglo XX, tienen su origen en las tácticas políticas del nuevo régimen, el llamado Nouveau regime, durante el siglo XIX francés, con Napoleón. Se revisa todo ello para entender fama y reconocimiento, sus consecuencias y repercusiones en el tiempo de Diego Rivera, es decir, el siglo XX. En diversos momentos se expone cómo lo ve la cultura oficial, así como sus contemporáneos y cómo actúa frente a todos ellos, ante las presiones y las críticas y frente a lo que él mismo expresa en sus declaraciones, cartas y textos de arte y política. El eje principal está puesto en el periodo que corresponde al sexenio del presidente Miguel Alemán Valdés, entre los años 1946 a 1952, ya que fue el momento culminante de la fama de Rivera, además de que en él se suscitaron los acontecimientos del máximo reconocimiento que el Estado le hizo al muralista: La exposición-homenaje por los cincuenta años de labor artística de Rivera, que se celebró en 1949 y el Premio Nacional de Ciencias y Artes en el año 1950, y las consecuencias de la crítica político-ideológica y la polémica que se produjo alrededor de su fama. La fama es una situación en la que está entrelazado un juego de poder entre el famoso y el Estado y en el que finalmente el artista está en desventaja, según la idea de Michel Foucault, quien propone que el poder de los intelectuales es una ilusión. La idea que trataré de mostrar es que a partir del Estado moderno, la Nación es quien debe otorgarle la honorabilidad a sus ciudadanos que, en apariencia, así lo merezcan, pero lo que en realidad importa es el lustre que dan esos hombres a un país.
El 68 y sus rutas de interpretación: una crítica historiográfica
Authors:   , Jiménez Guzmán Héctor
Published: March 2024

Esta investigación tiene como objetivo central el identificar y caracterizar los diversos modos en los que ha sido narrado, analizado e interpretado el movimiento estudiantil de 1968. Dicho de otro modo: pretendo relatar una historia sobre las historias del 68, poniendo el énfasis en lo que aquí llamaré rutas de la interpretación. He realizado esta investigación teniendo como hilo conductor la diversidad de obras y escritos que sobre el 68 se han publicado hasta 2008 en México. De este modo, he seleccionado una muestra representativa de lo que se ha escrito sobre aquellos acontecimientos para responder al problema general que guía esta investigación: ¿Cómo ha sido interpretado el movimiento estudiantil de 1968? A partir de este planteamiento central, se generaron otras preguntas específicas que he buscado resolver en este trabajo: ¿Cuáles fueron los cambios que fue experimentando la interpretación sobre el movimiento estudiantil de 1968?, ¿Cuáles son las características de las distintas interpretaciones que hay sobre el 68?, ¿Qué circunstancias sociales e históricas van favoreciendo dichos cambios?, ¿De quiénes han sido las versiones que se han hecho presentes en cada uno de los distintos cambios de la interpretación sobre el 68?, ¿Qué relaciones de poder guardan las distintas interpretaciones que se han ido manifestando a lo largo de los años?
12 profili klinicznych pacjentów, u których warto rozważyć zastosowanie kandesartanu
Authors: Barylski Marcin
Published: March 2024

Zgodnie z aktualnymi polskimi i europejskimi wytycznymi antagoniści receptora AT1 dla angiotensyny II należą do głównych grup leków stosowanych w terapii nadciśnienia tętniczego. Wiele badań wykazało, że sartany zmniejszają ryzyko wystąpienia powikłań nadciśnienia tętniczego, wywierają korzystny wpływ na profil metaboliczny, zmiany naczyniowe, funkcję nerek, a dodatkowo są najlepiej tolerowane spośród wszystkich preparatów hipotensyjnych. W artykule przedstawiono przykłady zastosowania kandesartanu w terapii nadciśnienia tętniczego, zwracając szczególną uwagę na jego skuteczność hipotensyjną, bezpieczeństwo stosowania u pacjentów w wieku podeszłym, korzystny wpływ na niewydolność serca, bóle migrenowe głowy czy przerost lewej komory.
Klarytromycyna w leczeniu zakażeń górnych dróg oddechowych
Authors: Radzikowski Andrzej
Published: March 2024

Klarytromycyna jest lekiem numer jeden we wszystkich przypadkach nietolerancji β-laktamów w terapii zakażeń dróg oddechowych, zwłaszcza w natychmiastowej alergii na amoksycylinę lub nienatychmiastowej na wszystkie β-laktamy, a także w innych formach nietolerancji. Ze względu na swą farmakokinetykę i farmakodynamikę może skutecznie zastąpić β-laktamy. W sytuacji wrażliwości na makrolidy klarytromycyna jest skutecznym eradykatorem paciorkowca ropotwórczego w anginie oraz pneumokoka i pałeczki hemofilnej w przypadkach ostrego zapalenia ucha środkowego i bakteryjnego zapalenia nosa i zatok, a także pozaszpitalnego zapalenia płuc. W przypadkach niejasnej etiologii pozaszpitalnego zapalenia płuc (typowej i/lub atypowej) jest cennym uzupełnieniem i wzmocnieniem β-laktamów w tzw. terapii kombinowanej.
Inhibitory DPP-4 – fakty i mity
Authors: Łebkowska Agnieszka
Published: March 2024

Inhibitory dipeptydylopeptydazy 4 (DPP-4, dipeptidyl peptidase-4), zwane gliptynami, należą do doustnych leków przeciwhiperglikemicznych, wymienianych w algorytmie leczenia cukrzycy typu 2 (T2DM, type 2 diabetes mellitus). Działają w oparciu o mechanizm inkretynowy i powodują szybkie i całkowite hamowanie enzymu DPP-4, przez co przyczyniają się do wzrostu stężenia endogennych inkretyn – glukagonopodobnego peptydu 1 oraz żołądkowego peptydu hamującego, a to w efekcie zwiększa wydzielanie insuliny, a zmniejsza glukagonu. Według aktualnych zaleceń Polskiego Towarzystwa Diabetologicznego dzięki bezpieczeństwu i dobrej tolerancji inhibitory DPP-4 stanowią wsparcie terapii T2DM na etapie jej intensyfikacji lub też w monoterapii w przypadku przeciwwskazań do stosowania innych grup leków przeciwhiperglikemicznych. W Polsce szeroko dostępne substancje z tej grupy to sitagliptyna i wildagliptyna. Wprowadzenie preparatów generycznych gliptyn oraz korzystne warunki refundacyjne umożliwiły szerszy dostęp do tej grupy leków.
Febuksostat – skuteczna i bezpieczna alternatywa leczenia dny moczanowej. Punkty widzenia kardiologa, reumatologa i nefrologa
Authors: Ozierański Krzysztof , Rupiński Robert , Małecki Robert
Published: March 2024

Febuksostat to silny inhibitor oksydazy ksantynowej stosowany w leczeniu przewlekłej hiperurykemii z odkładaniem się złogów moczanowych. Stanowi bardzo ważną alternatywę ze względu na bezpieczeństwo stosowania u pacjentów z chorobami przewlekłymi oraz wyższą skuteczność terapeutyczną od allopurynolu.
Skuteczne leczenie bólu i gorączki u dzieci – opisy przypadków
Authors: Sybilski Adam J.
Published: March 2024

Ból i gorączka to najczęstsze powody zgłaszania się rodziców z dziećmi do pediatry. Gorączka to nienormalny wzrost temperatury ciała występujący jako część specyficznej odpowiedzi biologicznej na chorobę. Ból i gorączkę leczymy u wszystkich dzieci, u których prawidłowo je zidentyfikowaliśmy i zinterpretowaliśmy, a nasze działanie ma przede wszystkim zmniejszyć dyskomfort i niepokój u pacjenta. Podstawowymi lekami w leczeniu bólu i łagodzeniu gorączki są paracetamol i ibuprofen (jako niesteroidowy lek przeciwzapalny), a ich skuteczność została potwierdzona w wielu badaniach klinicznych. W przypadku, gdy monoterapia w optymalnych dawkach nie powoduje skutecznego zmniejszenia bólu i gorączki, warto zastosować leczenie skojarzone (ibuprofen + paracetamol w jednym preparacie).
Wczesne stosowanie progesteronu w prewencji wybranych powikłań położniczych
Authors: Kwiatkowski Sebastian
Published: March 2024

Forma dopochwowa progesteronu zmniejsza ryzyko poronień u kobiet, które doświadczyły podobnych powikłań. Najlepsze wyniki można uzyskać dzięki zastosowaniu jej w pierwszym trymestrze ciąży. Bardzo obiecujące wyniki otrzymano także w prewencji stanu przedrzucawkowego.
Changes in Isoflavonoid and Flavonoid Content in Soybean Leaves Affected by UV-B or Copper
Authors: Trush Kristina , Handzušová Natália , Paľove-Balang Peter
Published: March 2024

The production of antioxidant flavonoids is an important aspect of plant defence mechanisms under stress conditions. The hypothesis of increased antioxidant flavonol quercetin and isoflavone content in soybean leaves subjected to UV-B irradiation and copper toxicity was proposed, and their accumulation was investigated using HPLC analysis. However, the accumulation of antioxidant quercetin was not induced by either UV-B irradiation or copper treatment. UV-B irradiation strongly induced isoflavone aglycones, mainly genistein, daidzein, formononetin, and to a lesser extent, biochanin A. Isoflavone glycosides, genistin and daidzin were also induced. Copper treatment, whether applied to leaves or root media, resulted in the accumulation of genistin and its malonylated form, whereas aglycones were only slightly affected. The higher accumulation of genistein over daidzein after copper treatment could be related to the higher chelating ability of genistein and its glycosides. Soybean isoflavones, which possess antioxidant and chelating properties, rather than flavonols, play a crucial role in the plant‘s defence mechanisms against both UV-B irradiation and copper toxicity.
Molecular Dynamics Simulation of KIT Mutation in a Patient wıth Piebaldism, Congenital Cataract and Aphakic Glaucoma
Authors: Duymus Fahrettin , Bozkurt Banu , Sahin Ali , Babayev Huseyin , Evans Sibel , Saylik Betul , Cora Tulin
Published: March 2024

Background: Piebaldism (OMIM #172800) is a rare autosomal dominant genodermatosis characterized by congenital poliosis and stable patches of leucoderma. Piebaldism is caused by mutations in the KIT and SNAI2 genes. The most common mutations are detected in the KIT gene.
Case presentation: A 5-year-old boy, who was followed-up for aphakic glaucoma after congenital cataract surgery, was consulted to the medical genetics and dermatology departments due to premature graying of the hair, white forelock in the frontal region of the scalp, whitening in the inner part of the eyebrows and eyelashes and patchy leukoderma with hyperpigmented islands inside on the extremities and trunk. DNA sequencing revealed a heterozygous missense c.1861G>A mutation in the KIT gene. Mutation was evaluated using in silico 3D-structure analysis and bioinformatics tools
Conclusion: KIT gene has a critical role in melanoblast migration, proliferation, differentiation and survival and molecular dynamics simulation and modeling proved that this variant inhibits the migration of melanoblasts and melanocytes by reducing the enzymatic activity of the KIT protein.
Introducción. Hacia una lectura transmoderna de la obra de Karl Marx ante los desafíos del siglo XXI
Authors: Colmenares Lizárraga Katya
Published: March 2024

Marx es uno de esos pensadores críticos de los que toda persona de izquierda cree saber algo. Marx abandonó la filosofía al superar el idealismo hegeliano y se dedicó a la economía para desarrollar el método científico del materialismo histórico. Mientras que para Hegel la realidad era espiritual, para Marx era material (física y económica), ya que, para Marx, lo primero es la materia y la conciencia es un derivado de ésta. A partir del método dialéctico hegeliano, el cual parte de la estructura «tesis, antítesis y síntesis», Marx desarrolló el método del materialismo dialéctico como determinación de la infraestructura sobre la superestructura. La comprensión de la historia que desarrolló el Marx definitivo advirtió a los procesos revolucionarios por venir que la línea histórica de las contradicciones como lucha de clases daría lugar al socialismo como culminación de la etapa capitalista.
Enrique Dussel: filósofo de la liberación de los pueblos
Authors: Colmenares Lizárraga Katya
Published: March 2024

Enrique Domingo Dussel Ambrosini (1934-2023), es el filósofo contemporáneo más importante del Sur global. Dejó más de 75 libros y 450 artículos, ha sido traducido al menos a 8 idiomas y es el más importante representante de la filosofía de la liberación, una filosofía crítica de alcance mundial al servicio de la liberación de las víctimas, los oprimidos y los excluidos ante cualquier sistema de dominación.
Juan José Bautista: pensar desde América Latina
Authors: Colmenares Lizárraga Katya
Published: March 2024

En este texto dibujaremos solo algunas líneas generales del retrato de un ser humano que nos ha dejado una enorme tarea, al haber abierto una nueva senda en la historia mundial de la filosofía y del pensamiento crítico. Juan José Bautista nació en La Paz, Bolivia el 27 de diciembre de 1958, su madre, Ana Hortensia Segales fue ama de casa, y su padre, Pablo Bautista, zapatero, ambos de origen aymara. Sería el tercero de cinco hermanos, y su crianza transcurrió entre La Paz y la isla de Anapia en el lago Titicaca, lugar que permaneció siempre como parte de las tierras de sus peregrinaciones.
Gambaran Perilaku Orang Tua dalam Menjaga Kesehatan Gigi dan Mulut Anak Tunagrahita Tingkat SD – SMP di SLB Negeri 2 Padang
Authors: Mulyani Aninda Putri , Ramayanti Sri , Putri Wulandani Liza
Published: March 2024

Introduction: Children with special needs, especially in groups of mentally retarded has greater risk of poor oral hygiene. Mental retardation is a term to describe individuals with below-average general intellectual functioning. Mental retardation and lack of coordination in movement in mentally retarded cause them haven’t skills to clean their teeth and mouth independently so they tend to be guided and cared by their parents. Objective: to describe behaviour of parents in maintaining the oral health of mentally retarded children at SD – SMP levels in SLBN 2 Padang. Methods: This study was categorical descriptive quantitative with cross sectional design. The number of samples is 40 respondents. Data were collected by filling out a questionnaire on how to maintain oral and dental health in mentally retarded children. Results: This study showed the level of knowledge of parents as much as 60% in the high category, attitudes of parents as much as 67% in the good category, and practices of parents as much as 47.5% in the moderate category. Conclusion: The level of behaviour of parents in maintaining the dental and oral health of mentally retarded children at the SD – SMP level in SLBN 2 Padang is in the good category.
Pengaruh Pendidikan Kesehatan Gigi dan Mulut terhadap Perilaku Orangtua dalam Memelihara Kesehatan Gigi dan Mulut Anak
Authors: Pujiyati Alfiyah , Cilmiaty Risya , Susanti Widia , Saptiwi Betty , Priyatno Adi
Published: March 2024

Background: The high prevalence of dental caries in preschool children is caused by various factors, including: knowledge, attitudes and behavior of parents. Preschoolers (93%) were included in severe early caries (dmf-t 8.43). Objective: To determine the effect of dental health education on parents' attitudes and behavior in maintaining the dental health of Joyosuran Kindergarten children. Method: Quasi-experimental research with one group pre-post test method. The sample is 38 people with total sampling method. The variables observed were changes in knowledge, attitudes and actions of parents before and after counseling. The data were tested with the Wilcoxon and Sommer d'gamma tests. Results: The results of the Wilcoxon test showed that there was a significant difference (p=0.000) between knowledge, attitudes and pre- and posttest actions with better post-test scores, while the Sommer d'gamma test results stated that there was no significant relationship between knowledge and attitudes (p sommer= p gamma=0.491), as well as knowledge and action (p sommer=p gamma = 0.686) (pre-test) of parents in maintaining children's oral and dental health. Conclusion: There are significant differences between the knowledge, attitudes and actions of pre- and post-intervention parents of Aisyiyah Joyosuran Kindergarten students.
O cuidado cultural no itinerário terapêutico de mulheres com sífilis
Authors: Nazareth Isis Vanessa , Silva Leila Rangel da , Teixeira Selma Villas Boas , Queiroz Ana Beatriz Azevedo , José Sabrina Ayd Pereira , Santos Inês Maria Meneses dos
Published: March 2024

Objetivo: Analisar o cuidado cultural no itinerário terapêutico de mulheres com sífilis fora do ciclo gravídico-puerperal.  Métodos: Baseado na Etnoenfermagem e utilizado o COREQ visando a qualidade estrutural da pesquisa. Selecionou-se mulheres registradas no Programa Municipal de DST/AIDS em Macaé/RJ e os profissionais da saúde que cuidam de mulheres com sífilis. Participaram vinte mulheres com diagnóstico de sífilis e sete profissionais de saúde. Coletou-se os dados entre janeiro e outubro de 2017. Utilizou-se dois capacitadores da Teoria do Cuidado Cultural e entrevista. A análise dos depoimentos fundamentou-se na Etnoenfermagem. Resultados: Conhecer o itinerário terapêutico através do cuidado cultural implicou em reconhecer os fatores culturais das mulheres e o contexto do ambiente em que vivem. Temática importante, pois, conhecer o itinerário terapêutico para a sífilis remete a uma responsabilidade de entender a cultura e o cuidado como dimensões inseparáveis do cuidado à saúde. Estudo possui limitações, não sendo adequado generalizar os resultados para outras localidades ou participantes. Conclusão: Na perspectiva transcultural identificou as respostas adaptativas para o cuidado da sífilis relacionados às características do contexto social e cultural das mulheres, como também refletir sobre respeitar o modo de vida no cuidado às mulheres com sífilis.
Orientações sobre infecções sexualmente transmissíveis em escolas do interior do Amazonas
Authors: Batista Jhenife Kelly de Souza , Severino Letícia Seixas , Silva Denise Souza da , Nunes Suzana dos Santos
Published: March 2024

Objetivo: Relatar a experiência de discentes de Enfermagem em um projeto de extensão sobre Infecções Sexualmente Transmissíveis realizado nas escolas estaduais de um município do interior do Amazonas. Relato de experiência: O presente relato refere-se à experiência das acadêmicas de Enfermagem nas atividades de extensão, que tiveram como público-alvo os discentes do 3° ano do ensino médio regular. De uma maneira leve e descontraída, foi abordado o tema Infecções Sexualmente Transmissíveis com imagens ilustrativas no PowerPoint, o qual versou sobre as formas de prevenção, destacando sempre o uso do preservativo feminino e masculino. A atividade foi finalizada com uma roda de conversa e com um convite aos alunos para a realização dos testes rápidos de HIV, sífilis, hepatite B e C. Considerações finais: O projeto proporcionou aos participantes vivenciar de perto a educação em saúde fora dos muros da universidade de modo que percebessem a real necessidade da atuação com diferentes públicos correlacionando o conhecimento adquirido em sala de aula e possibilitando-lhes um crescimento profissional.
Sintomas de depressão e ansiedade em estudantes de medicina de uma universidade pública de São Paulo: relação com a qualidade do sono
Authors: Tofanelli Laisa Prandine , Costa Pedro Rafael , Traslaviña Guillermo Andrey Ariza
Published: March 2024

Objetivo: Identificar a proporção de estudantes de medicina de uma universidade pública com sintomas de depressão, ansiedade, insônia, má qualidade do sono, e seus fatores determinantes. Métodos: Trata-se de um estudo transversal do tipo survey. Foi enviado um formulário com questões sociodemográficas e os questionários de qualidade do sono de Pittsburgh, sonolência de Epworth e ansiedade e depressão de Beck. A coleta de dados ocorreu entre agosto de 2021 e janeiro de 2022. Foi feita análise estatística descritiva e cálculo de medidas de associação. O estudo foi aprovado pelo Comitê de Ética em Pesquisa. Resultados: A amostra contou com 53 estudantes, predominando mulheres (52,8%), com idades entre 18 e 29 anos (84,9%), e de raça branca (67,9%). Os sintomas de depressão e ansiedade foram reportados por 83% e 50,9% dos participantes, respectivamente. Observou-se sonolência excessiva diurna em 15% dos estudantes, enquanto 77,4% pontuaram para má qualidade do sono. Demonstrou-se uma correlação positiva moderada entre sintomas de saúde mental e a escala de Pittsburgh. Os sintomas de depressão aumentaram a probabilidade de má qualidade do sono (OR 28,4; IC 95% 1,75-149). Conclusão:  Na população de estudantes de medicina, os sintomas de depressão podem comprometer negativamente a qualidade do sono.
Ação de educação alimentar e nutricional para promoção da saúde de adultos e idosos
Authors: Acerbi Matheus Carlos , Manfredi Flávia Veronezi , Florêncio Tatiane Silva , Miranda Nathaly Daquila , Alves Paula Pens , Faria Dayane Pêdra Batista de
Published: March 2024

Objetivo: Relatar a experiência de uma ação de educação alimentar e nutricional (EAN), direcionada a adultos e idosos, sobre os graus de processamento dos alimentos e as consequências para a saúde do consumo excessivo de alimentos processados e ultraprocessados. Relato de experiência: Foi realizada uma ação de EAN com grupo de adultos e idosos. Após a ação, foi realizada dinâmica com balões contendo perguntas sobre o tema abordado. Para o desenvolvimento da ação utilizou-se recursos visuais, com slides e uma maquete, contendo 15 alimentos com diferentes graus de processamento, sendo in natura e/ou minimamente processados, processados e ultraprocessados. Após a ação, foi entregue folder explicativo contendo regras de ouro e 10 passos para alimentação adequada e saudável. Considerações finais: Ação de EAN realizada com esse grupo promoveu a integração, despertou o interesse, aprofundou o entendimento teórico acerca do grau de processamento dos alimentos e nas consequências do consumo excessivo de alimentos processados e ultraprocessados, possibilitando a melhora do estado de saúde e na qualidade de vida dos participantes.
Socket-shield Technique and immediate implant placement for ridge preservation in the aesthetic region: a 1-year clinical and tomographic follow-up
Authors: Costa Marllus Alvarenga , Ghiraldini Bruna , Soares Michel Aislan Dantas , Crescencio Lívia Ramalho , Almeida Camila Saggioro de , Oliveira Lucas Viana de , Rosalém Gabriel Pereira , Vieira Esio , Machado Aldir Nascimento , Casado Priscila Ladeira
Published: March 2024

Objective: To describe the clinical, radiographic and tomographic aspects, as well as complications, success, aesthetic and functional results of an implant placed using the “socket shield” technique. Case Details: Represents a 46-year-old patient, with increased mobility of the crown in the bucco-palatal direction, with indication for extraction replaced by immediate implant. Atraumatic extraction, socket preservation technique and immediate implant placement were performed. The socket-shield technique was designed for placing implants to protect the oral bone and achieve adequate aesthetics. The buccal fragment of the tooth was kept fixed and the implant was placed in contact with the tooth fragment. Cone Bean computed tomography showed bone formation in the buccal aspect 1 year later, and demonstrated stability of the peri-implant bone tissue and replacement of the root remnant by bone. The clinical appearance demonstrated maintenance of peri-implant soft tissues and good aesthetics without gingival retraction. Final considerations: One-year follow-up shows adequate healing and healthy peri-implant tissue, suggesting that the socket-shield technique with immediate implant placement can be an excellent alternative for preserving the vestibular cortex and implant placement, especially in the aesthetic area.
Impactos de dispositivos tecnológicos avançados para o autocuidado e monitoramento de pacientes ostomizados
Authors: Pereira Valéria de Santana , Madeira Julyana Falcão , Oliveira Chrystianne da Silva , Silva Stefanne Moraes Gomes da , Cavalcanti Andréa de Oliveira Ribeiro , Nascimento José William Araújo do
Published: March 2024

Objetivo: Analisar e sintetizar as evidências disponíveis na literatura sobre o impacto de dispositivos tecnológicos avançados no autocuidado e monitoramento de pacientes ostomizados. Métodos: Trata-se de uma revisão integrativa, realizada nas bases de dados EMBASE, PubMed, Scopus e Web of Science, por meio dos seguintes descritores: “ostomy”, “colostomy”, “ileostomy”, “abdominal stoma”, “information systems”, “e-health”, “wearable electronic devices” e “mobile applications”. Foram incluídos estudos publicados entre 2018 a 2023 que avaliaram a aplicação de tecnologias de informação especificamente projetadas para indivíduos vivendo com ostomias intestinais. Resultados: Oito artigos compuseram a amostra final deste estudo, com maior frequência de estudos pilotos (n: 02). Foram examinadas intervenções tecnológicas como sensores portáteis, aplicativos móveis, chatbots e algoritmos de IA para os ostomizados. Os estudos indicaram melhorias na qualidade de vida, ajustamento psicossocial e manejo de complicações, apesar de enfrentarem desafios como precisão e usabilidade das tecnologias. Considerações finais: Esta revisão destacou o potencial significativo de dispositivos tecnológicos avançados no cuidado de pacientes ostomizados, melhorando a qualidade de vida e o autocuidado. Apesar dos avanços, desafios como precisão e adaptação das tecnologias a diversas condições clínicas permanecem.
Periprocedural management of ruptured blister aneurysms treated with pipeline flow diversion
Authors: Hoffman Jessa E. , Morel Brent , Wittenberg Blake , Kumpe David , Seinfeld Joshua , Folzenlogen Zach , Case David , Neumann Robert , Cava Luis , Breeze Robert , Wiley Laura , Roark Christopher
Published: March 2024

Background:

Blister aneurysms are high-risk intracranial vascular lesions. Definitive treatment of these lesions has been challenging. Severe disability or mortality rates are as high as 55% when these lesions are treated with open surgery. Recent data show that flow diversion is a safe and effective alternative treatment for blister aneurysms. Rerupture of the functionally unsecured lesion remains a concern as flow diversion does not immediately exclude the aneurysm from the circulation.

Methods:

A retrospective review was performed of any patients with ruptured blister aneurysms treated with a pipeline embolization device between 2010 and 2020 at the University of Colorado.

Results:

In this paper, we present the results of the intensive care management of ruptured intracranial blister aneurysms after flow-diverting stent placement.

Conclusion:

Despite the need for dual antiplatelet therapy and the delayed occlusion of blister aneurysms treated with flow diversion, we did not find an increase in periprocedural complications.
The role of preoperative hematological inflammatory markers as a predictor of meningioma grade: A systematic review and meta-analysis
Authors: Rusidi Hanan Anwar , Rosyidi Rohadi Muhammad , Wardhana Dewa Putu Wisnu , Baskoro Wisnu , Ramadhana Geizar Arsika
Published: March 2024

Background:

Inflammatory processes play an important role in the aggressiveness of a tumor. However, the relationship between inflammatory markers in meningioma grade is not well known. Knowledge of preoperative meningioma grade plays an important role in the prognosis and treatment of this tumor. This study aims to assess preoperative hematological inflammatory markers as a predictor of the pathological grade of meningioma.

Methods:

To ensure comprehensive retrieval of relevant studies, we searched the following key databases, PubMed, Science Direct, and Biomed Central, with evidence related to preoperative hematological inflammatory markers among meningioma up to September 2023. The studies involved were selected based on established eligibility criteria. The analysis in this study uses Review Manager 5.4

Results:

Six studies were obtained from the search results. The total number of patients 2789 (469 high-grade meningioma and 2320 low-grade meningioma) analysis shows elevated neutrophil-to-lymphocyte ratio (NLR) (mean difference [MD]: 0.29; 95% confidence interval [CI] 0.13–0.45; P = 0.0004), monocyte-to-lymphocyte ratio (MLR) (MD: 0.02; 95% CI 0.00–0.04; P = 0.003), and low lymphocyte-to-monocyte ratio (LMR) (MD: −0.82; 95% CI −1.46–−0.18; P = 0.005) significantly associated with high-grade meningioma compared to low-grade meningioma. No significant correlation between high-grade and low-grade meningioma based on platelet-lymphocyte ratio value is observed.

Conclusion:

The parameters of NLR, MLR, and LMR have been found to be cost-effective preoperative methods that demonstrate potential value in the prediction of meningioma grade. To enhance the reliability of the findings, it is imperative to do further prospective study.
Three components: one-pot synthesis of tetrazoles using silica-supported melamine tri-sulfonic acid, an efficient and reusable heterogeneous catalyst
Authors: Tailor Hetal , Limbachiya Pruthviraj , Mahajan Dharmesh H.
Published: March 2024

The effective and straightforward procedure for synthesizing 1-H 1,2,3,4 tetrazole involves the reaction of a primary amine, triethyl orthoformate and sodium azide in the presence of silica-supported melamine tri sulfonic acid. One pot synthesis of tetrazole derivatives over the silica-supported melamine tri sulfonic acid catalyst reveals that the existence of strong acid sites in silica makes it more efficient with respect to the shortening of the reaction time (5–6 h) and excellent yield (75-84%) as compared to the other catalysts. This process includes benefits like a more environmentally friendly path, an easier work-up, a reusable catalyst and a high yield.
Application of High-Performance Computing to Solve the Cauchy problem with the Fractional Riccati Equation Using an Nonlocal Implicit Finite-Difference Scheme
Authors: Твёрдый Д.А. , Паровик Р.И.
Published: March 2024

В статье представлено исследование вычислительной эффективности параллельной версии численного алгоритма для решения уравнения Риккати с производной дробного перменного порядка типа Герасимова-Капуто. Численный алгоритм представляет собой нелокальную неявную конечно-разностную схему, которая сводится к системе нелинейных алгебраических уравнений и решается с помощью модифицированного метода Ньютона. Нелокальность численной схемы создает высокую вычислительную нагрузку на вычислительные ресурсы, из-за чего возникает необходимость в реализации эффективных параллельных алгоритмов их решения. Исследуемый на эффективность численный алгоритм реализован на языке C из-за его универсальности при работе с памятью. Распаралеливание проводилось с помощью технологии OpenMP. Проводится серия вычислительных экспериментов на вычислительном сервере NVIDIA DGX STATION (Институт математики имени В.И. Романовского, г. Ташкент, Узбекистан) и ноутбуке HP Pavilion Gaming Laptop Z270X, где решалась задача Коши для дробного уравнения Риккати с непостоянными коэффициентами. На основе среднего времени вычисления вычисляются: ускорение, эффективность и стоимость алгоритма. Из анализа данных видно, что OpenMP параллельная программная реализация нелокальной неявной конечно-разностной схемы показывает ускорение работы от 9-12 раз в зависимости от количества задействованных ядер CPU.

The article presents a study of the computational efficiency of a parallel version of a numerical algorithm for solving the Riccati equation with a fractional variable order derivative of the Gerasimov-Caputo type. The numerical algorithm is a nonlocal implicit finite-difference scheme, which reduces to a system of nonlinear algebraic equations and is solved using a modified Newton method. The nonlocality of the numerical scheme creates a high computational load on computing resources, which creates the need to implement efficient parallel algorithms for solving them. The numerical algorithm studied for efficiency is implemented in the C language due to its versatility when working with memory. Parallelization was carried out using OpenMP technology. A series of computational experiments are being carried out on the NVIDIA DGX STATION computing server (Institute of Mathematics named after V.I. Romanovsky, Tashkent, Uzbekistan) and the HP Pavilion Gaming Laptop Z270X, where the Cauchy problem for the fractional Riccati equation with non-constant coefficients was solved. Based on the average computation time, the speedup, efficiency and cost of the algorithm are calculated. From the data analysis it is clear that the OpenMP parallel software implementation of the non-local implicit finite-difference scheme shows an acceleration of 9-12 times, depending on the number of CPU cores involved.
A mikrobiom és a kardiovaszkuláris egészség
Authors: Péterfi Zoltán
Published: March 2024

A bél mikrobiom fontos szerepet játszik számos betegség kialakulásában vagy annak progressziójában. Egy kevésbé ismert terület a kardiovaszkuláris rendszer betegségei és a mikrobiom közötti kapcsolat, a bél–szív tengely és ateroszklerózis kapcsolata. A bél mikrobiom hatását különböző közvetítő molekulákon, mint a lipopoliszacharid, trimetilamin, fenilactetil-glutamin, rövid szénláncú zsírsavak, másodlagos epesavak, keresztül fejti ki. A legtöbb hatás, nem közvetlen, hanem az anyagcsere-folyamatok megváltoztatásán keresztül érvényesül és tartós folyamat eredménye, ezért vizsgálata és az összefüggések bizonyítása is nehézségekbe ütközik. A bél mikrobiom egyensúlyának helyreállítása segíthet a kóros folyamatok megállításában vagy azok visszafordításában. Jelen közleményben összefoglaljuk az eddigi ismereteinket a mikrobiom anyagcseretermékeinek kardiovaszkuláris rendszerre való hatásáról, valamint a rendelkezésünkre álló lehetőségeket a kóros hatások kivédése érdekében.
Kardiovaszkuláris rizikóstratifikációs szisztéma a diabetes mellitusban szenvedők számára – az ESC Diabetes guideline alapján
Authors: Vértes András
Published: March 2024

Az Európai Kardiológiai Társaság kardiovaszkuláris betegségek megelőzésére vonatkozó irányelvei a SCORE2 kockázati index használatát javasolják a klasszikus SCORE kockázati index helyett a kardiovaszkuláris kockázat – a 10 éves fatális és nem fatális kimenetelű kockázatok – becsléséhez az egészséges populációban 70 éves életkorig. A 2 típusú diabetes mellitusban szenvedő betegek esetében 2-4-szer nagyobb kockázatnak vannak kitéve a szív- és érrendszeri betegségek kialakulására. Számos ateroszklerózisban szenvedő betegnek nem diagnosztizált cukorbetegsége van. A SCORE2-Diabetes, a 2-es típusú cukorbetegségben szenvedő betegek szív- és érrendszeri betegségek 10 éves fatális és nem fatális kardiovaszkuláris kockázatának előrejelzésére kifejlesztett, kalibrált és validált új algoritmus Európa-szerte javítja a szív- és érrendszeri betegségek kialakulásának nagyobb kockázatának kitett betegek korai meghatározását.
Szex és aritmiák
Authors: Kardos Attila
Published: March 2024

A szexuális aktivitás közben fellépő hirtelen szívhalál ritka esemény, ugyanakkor a kockázati csoportokat illetően demográfiai változások tanúi lehetünk. A legújabb tanulmányok rávilágítottak arra, hogy a szexuális tevékenység során előforduló kardiális események egyre fiatalabbakat érintenek, a női elhunytak aránya a korábban leírtaknál nagyobb. Párbeszédre van szükség a kardiovaszkuláris személyzet és a betegek között, így jöhet csak létre a szükséges felvilágosítás, és megnyugtatás a biztonságos szexuális életet illetően. Jelen cikk áttekinti, hogyan vezethet a szexuális aktivitás a szívritmuszavarok és a hirtelen szívmegállás kockázatának növekedéséhez nem optimálisan kezelt vagy nem kellően informált betegeknél. A leggyakoribb szív- és érrendszeri betegségeknél tárgyalja a szexuális együttlét által kiváltott szívritmuszavarok és hirtelen szívhalál lehetséges kockázatait és ezek pszichoszociális hatásaival is foglalkozik. Végül a szív- és érrendszeri gyógyszerek és a beültethető kardioverter defibrillátorok (ICD-k) biztonságosságával kapcsolatos szakirodalmat tekinti át. Összességében a szexuális tevékenység biztonságos a legtöbb szívbeteg számára, és a megfelelő oktatás a beteg és partnere számára magasabb kockázatú szív- és érrendszeri betegség esetén is megnyugtató nemi életet biztosít. Nem lehet eléggé hangsúlyozni a beteg kellő informáltságát azokról a tényezőkről, amelyek a szexuális tevékenység során szívritmuszavarokat és hirtelen szívmegállást válthatnak ki. Az egészségügyi szolgáltatóknak lehetőség szerint beszélni kell minden beteggel, és biztosítani őket, hogy szexuális partnerek, nőbetegek és az LMBTQIA + közösség tagjai ugyanilyen hozzáférést kapnak a tanácsadáshoz egyéni szükségleteikre szabva.