bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengaruh Kompetensi, Integritas dan Koordinasi terhadap Efektivitas Kerja Anggota Dewan Perwakilan Rakyat Daerah Kota Tangerang Selatan
Authors: Bastian Ricky Yuanda , Rangkuti Zulkifli , Pratikno Yuni
Published: September 2024

The Influence of Competence, Integrity and Coordination on the Work Effectiveness of Members of the Regional People's Representative Council of South Tangerang City. The work effectiveness of council members is not yet optimal in the Regional People's Representative Council (DPRD) of South Tangerang City. Integrity, competence and coordination factors dominantly influence the work effectiveness of board members. This research aims to analyze the magnitude of the influence of competence, integrity and coordination on the work effectiveness of members of the South Tangerang City Regional People's Representative Council. The research approach applied is quantitative, namely research that emphasizes analysis on numerical data or numbers obtained using statistical methods. This research uses survey methods and explanatory/causal analysis. The sample was members of the South Tangerang City DPRD, namely 50 members of the Council. Analysis using multiple linear regression analysis. The results of the analysis show that there is a significant influence of competence, integrity and coordination on the work effectiveness of members of the Regional People's Representative Council of South Tangerang City, both individually and simultaneously.
Peran Guru dalam Penerapan Projek Penguatan Profil Pelajar Pancasila terhadap Budaya Positif di Sekolah Dasar Negeri 241 Palembang
Authors: Firdiansyah Firdiansyah , Ahyani Nur , Mahasir Mahasir
Published: September 2024

This research examines the role of teachers in implementing a project to strengthen students' Pancasila profiles towards fostering a positive culture at SD Negeri 241 Palembang. The research aims to explore how teachers contribute to shaping students' understanding and realization of Pancasila values, thus encouraging the creation of a positive cultural environment in schools. Through qualitative methods, including interviews and observations, this research examines teachers' strategies, the challenges they face, and their impact on student attitudes and behavior. The findings show that teachers play an important role in instilling Pancasila values, influencing students' cultural perceptions, and fostering a conducive learning atmosphere in line with national ethos and moral values. This research underlines the importance of teacher involvement in character education and its implications in creating a harmonious school environment that is rooted in Indonesian cultural values.
THE DYNAMICS OF HEALTH-RELATED QUALITY OF LIFE (HRQoL) IN WORKING GRADUATE STUDENTS OF PSYCHOLOGY
Authors: SHOLEH MOH. , QOWIMAH SIRRI NAHZATUN
Published: September 2024

This study focuses on the Health-Related Quality of Life (HRQoL) of working psychology graduate students. It aims to delve deeper into their experiences in managing HRQoL and the strategies they use to maintain a healthy quality of life. Using a phenomenological qualitative approach, the study explores the subjective experiences of two students who are pursuing graduate studies while working. The findings indicate that the combination of academic and work responsibilities impacts the physical and mental well-being of the students. Both participants employed time management strategies and adapted to different environments to maintain their HRQoL, despite ongoing pressures. In conclusion, working graduate students face significant challenges in maintaining their HRQoL, but with the right strategies, they can manage these pressures effectively.
INVESTIGATION OF THE POSITIONAL COMPETITION LEVELS OF U17 – U19 AND A-TEAM FOOTBALL PLAYERS
Authors: GÜL MINE , VATANSEVER AHMET , ALPAT OĞUZHAN
Published: September 2024

By measuring the reflections of competition in football, it is aimed to determine the status of factors that directly affect individual and team performance, such as development effort, teammate support, supporting a teammate, communication, personal awareness, knowing the coach and coach preference. In the study, the "Positional Competition Scale in Sports" was applied to the football players. While there are differences compared to other athletes in the categories of teammate support and coach preference of football players between the ages of 14-16, there are differences compared to other athletes in the sub-categories of development effort and self-awareness of football players in the 14-16 age group. Get 1-3 years of education in the education age category. When the team category was evaluated, it was determined that the U19 and U17 groups made a difference in the teammate support and coach preference subcategory. There seems to be a general difference in forwards compared to defenders and midfielders. As a result, it is understood that young athletes have more in-team group support in terms of regular training process, and that they make significant progress in the development effort categories in terms of being included in the team and taking responsibility, compared to other subgroups. and self-awareness.
Quantum-to-classical modeling of monolayer Ge2Se2 and its application in photovoltaic devices
Authors: Shrivastava Anup , Saini Shivani , Kumari Dolly , Singh Sanjai , Adam Jost
Published: September 2024

Since the discovery of graphene in 2004, the unique properties of two-dimensional materials have sparked intense research interest regarding their use as alternative materials in various photonic applications. Transition metal dichalcogenide monolayers have been proposed as transport layers in photovoltaic cells, but the promising characteristics of group IV–VI dichalcogenides are yet to be thoroughly investigated. This manuscript reports on monolayer Ge2Se2 (a group IV–VI dichalcogenide), its optoelectronic behavior, and its potential application in photovoltaics. When employed as a hole transport layer, the material fosters an astonishing device performance. We use ab initio modeling for the material prediction, while classical drift–diffusion drives the device simulations. Hybrid functionals calculate electronic and optical properties to maintain high accuracy. The structural stability has been verified using phonon spectra. The E–k dispersion reveals the investigated material’s key electronic properties. The calculations reveal a direct bandgap of 1.12 eV for monolayer Ge2Se2. We further extract critical optical parameters using the Kubo–Greenwood formalism and Kramers–Kronig relations. A significantly large absorption coefficient and a high dielectric constant inspired the design of a monolayer Ge2Se2-based solar cell, exhibiting a high open circuit voltage of Voc = 1.11 V, a fill factor of 87.66%, and more than 28% power conversion efficiency at room temperature. Our findings advocate monolayer Ge2Se2 for various optoelectronic devices, including next-generation solar cells. The hybrid quantum-to-macroscopic methodology presented here applies to broader classes of 2D and 3D materials and structures, showing a path to the computational design of future photovoltaic materials.
Hydrogen-bond activation enables aziridination of unactivated olefins with simple iminoiodinanes
Authors: Thai Phong , Patel Lauv , Manna Diyasha , Powers David C
Published: September 2024

Iminoiodinanes comprise a class of hypervalent iodine reagents that is often encountered in nitrogen-group transfer (NGT) catalysis. In general, transition metal catalysts are required to effect efficient NGT to unactivated olefins because iminoiodinanes are insufficiently electrophilic to engage in direct aziridination chemistry. Here, we demonstrate that 1,1,1,3,3,3-hexafluoroisopropanol (HFIP) activates N-arylsulfonamide-derived iminoiodinanes for the metal-free aziridination of unactivated olefins. 1H NMR and cyclic voltammetry (CV) studies indicate that hydrogen-bonding between HFIP and the iminoiodinane generates an oxidant capable of direct NGT to unactivated olefins. Stereochemical scrambling during aziridination of 1,2-disubstituted olefins is observed and interpreted as evidence that aziridination proceeds via a carbocation intermediate that subsequently cyclizes. These results demonstrate a simple method for activating iminoiodinane reagents, provide analysis of the extent of activation achieved by H-bonding, and indicate the potential for chemical non-innocence of fluorinated alcohol solvents in NGT catalysis.
ANALISIS PENYEMPITAN JALAN TERHADAP KARAKTERISTIK ARUS LALU LINTAS PADA JALAN GAJAH MADA BATAM
Authors: Muhammad Febri Muslim  , Herlina Suciati  , Edi Indera  , Akhbar Ilmiah Room
Published: September 2024

Batam City's strategic position between the Strait of Malacca and the Strait of Singapore makes it a center of economic and trade activities that continues to grow rapidly. This rapid economic growth has led to an increase in infrastructure needs, including roads and transportation systems. One of the problems faced by Batam City is the narrowing of roads which causes an increase in traffic density. This study aims to determine the relationship of traffic flow characteristics and identify the maximum flow value and maximum density on normal and narrowed road sections. The research data were collected through field survey for one week. Data analysis was conducted based on the guidelines of the 1997 Indonesian Road Capacity Manual (MKJI). To analyze the relationship between volume, speed, and density, two models were used: the Greenshields model and the Greenberg model. Based on the results of data analysis, the coefficient of determination on normal road segments for the Greenshields model is r² = 1.000 and for the Greenberg model is r² = 0.941. While on the narrowed road segment, the coefficient of determination for the Greenshields model is r² = 1.000 and for the Greenberg model is r² = 0.929. Thus, the calculation results show that the Greenshields model provides better results because it has a higher coefficient of determination than the Greenberg model.
Delirium en el anciano: guía clínica integral para su diagnóstico y tratamiento
Authors: Sarmiento Dickson Danna , Ordosgoitia Dickson Luis Felipe , Álzate Hoyos Daniela , Santana Araujo Sebastián Enrique , Herdenes García Daniela María , Ibarra Olivella Eyver Enrique , Vergara Serpa Oscar
Published: September 2024

Introducción: Los ancianos tienen un mayor riesgo de presentar delirium debido a factores como la edad avanzada, demencia y deterioro cognitivo y funcional. Su prevalencia varía según el grupo de pacientes y el entorno. Objetivo: Sintetizar y analizar críticamente el conocimiento actual sobre la definición, características clínicas, diagnóstico y tratamiento del delirium en ancianos. Metodología: Se realizó una búsqueda sistemática en bases de datos, utilizando términos MeSH y DeCs: “Delirium”, “Cognitive Dysfunction”, “Dementia”, “Aged”, “Clinical Protocols” y “Coronavirus Infections”. Se incluyeron artículos publicados hasta el 30 de mayo de 2021, seleccionando 50 artículos basados en criterios de inclusión y exclusión establecidos por los autores. Resultados: En los ancianos, el delirium ocurre por una falla cerebral que reduce la capacidad de respuesta a un factor estresante agudo, siendo la disfunción colinérgica el mecanismo más frecuente. Es común en pacientes hospitalizados, con una prevalencia del 23% en pacientes no quirúrgicos. En pacientes postquirúrgicos, la prevalencia varía, alcanzando hasta un 20% en aquellos sometidos a cirugía mayor. Las restricciones generadas por la pandemia de COVID-19 aumentaron la incidencia de delirium en ancianos, presentándose de manera más severa. Es esencial usar herramientas estandarizadas para la detección del delirium en la práctica clínica. No existen pruebas de laboratorio específicas para su diagnóstico y no se recomienda de rutina el uso de estudios de neuroimagen. Las estrategias no farmacológicas con componentes múltiples han demostrado reducir su incidencia. Conclusión: El delirium es una condición multifactorial que genera alta morbimortalidad en los ancianos. El manejo farmacológico sigue siendo un desafío en su tratamiento
Agroforestry Model in Leimea Sorin Village, Emerera District, Timor Leste
Authors: SOARES Cristina
Published: September 2024

Agroforestry is an optimal and sustainable management of land use, by combining forestry and agricultural activities on the same land management unit by taking into account physical, social and economic environmental conditions. The purpose of this study is to calculate the value of farmers' income from the results of the agroforestry model, and the best feasibility analysis on consideration of three factors, namely economic, social and ecological. This research was carried out in the village of Leimea Sorin, Ermera District, Timor Leste in March-May 2021 using qualitative and quantitative methods. The data used in this study are data obtained directly from agroforestry farmers in the Ermera district of Timor Leste by means of interviews with the help of a questionnaire. Economic data analysis using three criteria NPV, BCR and IRR, and social and ecological analysis using qualitative descriptive. The results of the financial analysis show that the NPV is $ 220,184.66, the BCR is 28.7 and the IRR is 35%. The results of the social analysis show that the social aspect in the application of agroforestry in the village of Leimea Sorin Balu is the local community of the Kemak ethnic group of agricultural crops as their daily livelihood such as vanilla, coffee, teak, and others. And the ecological aspect is the results of the study show that the agroforestry model in the village of Leimea Sorin is an agroforestry system that has polycultural properties, and provides various benefits for the community compared to non-agroforestry systems.
The Role of Employee Engagement Mediating Digital Leadership and Organizational Support on Employee Performance at Siloam Bali Hospital
Authors: MARIANI Kadek Lina , SANTOSO R Tri Priyono Budi , KOMALASARI Yeyen , JUNAEDI I Wayan Ruspendi
Published: September 2024

Purpose:The research on this occasion aimed to determine the influence of digital leadership and organizational support on employee performance, mediated by employee involvement among Siloam Hospital Bali employees.
Methodology :The method used in carrying out this research is a quantitative approach. The sample that supports this research is employees recorded as working at Siloam Hospital Bali with a total of 84 data. The techniques used to make searching and collecting data easier are questionnaires, interviews and documentation accompanied by observation. The analytical technique used to answer the hypothesis is quantitative descriptive analysis and Partial Least Square (PLS) applying the Structural Equation Modeling (SEM) equation model.
Findings :The results of this series of research show that 1) digital leadership without providing results influences employee engagement, 2) digital leadership without providing results influences employee performance, 3) organizational support provides results with a positive influence and occurs significantly on employee engagement, 4) organizational support provides results with a positive influence and significant attitude on employee performance.
Implication :5) employee engagement provides results with a positive influence and significant relationship on employee performance, 6) employee engagement without being able to mediate the influence of digital leadership on employee performance, 7) engagement employees succeeded in mediating the influence of organizational support on employee performance.
Optical Variability Properties of Southern TESS Blazars
Authors: Dingler Ryne , Smith Krista Lynne
Published: September 2024

We present a study of high-cadence, high-precision optical light curves from the TESS satellite of 67 blazars in the southern sky. We provide descriptive flux statistics, power spectral density (PSD) model parameters, and characteristic variability timescales. We find that only 15 BL Lacertae objects (BLLs) and 18 flat spectrum radio quasars (FSRQs) from the initial 26 and 41, respectively, exhibit statistically significant variability. We employ an adapted power spectral response method to test the goodness of fit for the PSD function to three power-law variant models. From our best-fitting description of the PSD, we extract the high-frequency power-spectral slopes, and if present, determine the significant bend or break in the model to identify characteristic timescales. We find no significant difference in the excess variance or rms scatter between blazar subpopulations. We identify a linear rms–flux relation in ∼69% of our sample, in which ∼20% show a strong correlation. We find that both subpopulations of blazars show power spectral slopes of α ∼ 2 in which a broken power-law best fits five BLLs and six FSRQs and a bending power-law best fits one BLL and five FSRQs. The shortest timescales of variability in each light-curve range widely from minutes to weeks. Additionally, these objects’ characteristic timescales range from ∼0.8 to 8 days, consistent with optical variability originating in the jet.
Testing the ΛCDM Cosmological Model with Forthcoming Measurements of the Cosmic Microwave Background with SPT-3G
Authors: Prabhu K. , Raghunathan S. , Millea M. , Lynch G. P. , Ade P. A. R. , Anderes E. , Anderson A. J. , Ansarinejad B. , Archipley M. , Balkenhol L. , Benabed K. , Bender A. N. , Benson B. A. , Bianchini F. , Bleem L. E. , Bouchet F. R. , Bryant L. , Camphuis E. , Carlstrom J. E. , Cecil T. W. , Chang C. L. , Chaubal P. , Chichura P. M. , Chokshi A. , Chou T.-L. , Coerver A. , Crawford T. M. , Cukierman A. , Daley C. , de Haan T. , Dibert K. R. , Dobbs M. A. , Doussot A. , Dutcher D. , Everett W. , Feng C. , Ferguson K. R. , Fichman K. , Foster A. , Galli S. , Gambrel A. E. , Gardner R. W. , Ge F. , Goeckner-Wald N. , Gualtieri R. , Guidi F. , Guns S. , Halverson N. W. , Hivon E. , Holder G. P. , Holzapfel W. L. , Hood J. C. , Hryciuk A. , Huang N. , Kéruzoré F. , Knox L. , Korman M. , Kornoelje K. , Kuo C.-L. , Lee A. T. , Levy K. , Lowitz A. E. , Lu C. , Maniyar A. , Menanteau F. , Montgomery J. , Nakato Y. , Natoli T. , Noble G. I. , Novosad V. , Omori Y. , Padin S. , Pan Z. , Paschos P. , Phadke K. A. , Pollak A. W. , Quan W. , Rahimi M. , Rahlin A. , Reichardt C. L. , Rouble M. , Ruhl J. E. , Schiappucci E. , Smecher G. , Sobrin J. A. , Stark A. A. , Stephen J. , Suzuki A. , Tandoi C. , Thompson K. L. , Thorne B. , Trendafilova C. , Tucker C. , Umilta C. , Vitrier A. , Vieira J. D. , Wan Y. , Wang G. , Whitehorn N. , Wu W. L. K. , Yefremenko V. , Young M. R. , Zebrowski J. A.
Published: September 2024

We forecast constraints on cosmological parameters enabled by three surveys conducted with SPT-3G, the third-generation camera on the South Pole Telescope. The surveys cover separate regions of 1500, 2650, and 6000 deg2 to different depths, in total observing 25% of the sky. These regions will be measured to white noise levels of roughly 2.5, 9, and

12

μ
K

-armin, respectively, in cosmic microwave background (CMB) temperature units at 150 GHz by the end of 2024. The survey also includes measurements at 95 and 220 GHz, which have noise levels a factor of ∼1.2 and 3.5 times higher than 150 GHz, respectively, with each band having a polarization noise level

∼

2

times higher than the temperature noise. We use a novel approach to obtain the covariance matrices for jointly and optimally estimated gravitational lensing potential band powers and unlensed CMB temperature and polarization band powers. We demonstrate the ability to test the ΛCDM model via the consistency of cosmological parameters constrained independently from SPT-3G and Planck data, and consider the improvement in constraints on ΛCDM extension parameters from a joint analysis of SPT-3G and Planck data. The ΛCDM cosmological parameters are typically constrained with uncertainties up to ∼2 times smaller with SPT-3G data, compared to Planck, with the two data sets measuring significantly different angular scales and polarization levels, providing additional tests of the standard cosmological model.
Rotation of Polarization Angle in Gamma-Ray Burst Prompt Phase. II. The Influence of the Parameters
Authors: Li Jia-Sheng , Wang Hao-Bing , Lan Mi-Xiang
Published: September 2024

In addition to the light curve and energy spectrum, polarization is also important for inferring the physical properties of the gamma-ray burst (GRB). Rotation of the polarization angle (PA) with time will cause depolarization of the time-integrated polarization degree. However, it has rarely been studied before. Here, we use a magnetic reconnection model with a large-scale ordered aligned magnetic field in the emitting region to study the influence of the parameters on the PA rotations in the GRB prompt phase. We find that the half-opening angle of the jet θ

j
, the observational angle θ

V
, and the bulk Lorentz factor Γ all have significant impacts on the PA rotations. The PA rotations are affected by the product value of θ

j
Γ0 (Γ0 is the normalization factor of Γ with

Γ

(
r
)
=

Γ

0

(
r

/

r

0

)

s

), but are roughly independent of the concrete values of both θ

j
and Γ0. For the typical parameters, the changes of the PA within T
90 (△PA) would be within (12°, 66°) for slight off-axis observations, where T
90 is the duration of the burst with the accumulated flux density ranging from 5% to 95%. The q range for △PA > 10° becomes smaller with the increase of the product value of θ

j
Γ0. The most significant PA rotation with △PA ∼ 90° will happen when θ

j
Γ0 > 50 and 1.0 < q ≤ 1.2.
Cometary Activity from Minor Planet 2015 VP51 Discovered with Citizen Science
Authors: Frissell Maxwell K. , Chandler Colin Orion , Oldroyd William J. , Trujillo Chadwick A. , Sedaghat Nima , Burris William A. , Kueny Jay K. , DeSpain Jarod A. , Farrell Kennedy A. , Hsieh Henry H. , Magbanua Mark Jesus Mendoza , Sheppard Scott S. , Mazzucato Michele T. , Bosch Milton K. D. , Shaw-Diaz Tiffany , Gonano Virgilio , Lamperti Al , da Silva Campos José A. , Goodwin Brian L. , Terentev Ivan A. , Dukes Charles J. A.
Published: September 2024

We report the discovery of cometary activity emanating from minor planet 2015 VP51 outbound from its recent perihelion passage. The activity, in the form of a diffuse tail, was first identified by volunteers of our Citizen Science program Active Asteroids, a NASA Partner program hosted on the Zooniverse platform. This discovery was aided by the recently implemented TailNet artificial intelligence assistant which filters out images with a low likelihood of showing cometary activity. The tail is present in nine images of 2015 VP51 from the Dark Energy Camera and OmegaCAM between UT 2015 August 2 and UT 2015 October 18. We classify 2015 VP51 as a Jupiter-family comet based on its Tisserand parameter with respect to Jupiter T
J = 2.931.
Enhancement of nutritional characteristics of Tartary buckwheat (Fagopyrum tataricum) sprouts, passion and pineapple juice fermented by yeast (Saccharomyces cerevisiae) and Lactobacillus plantarum
Authors: Han Xiao , Ma Gen , Fu Xiao-qin , Zou Xin , Zhang Jie-yu , Wen Jie , Fan Yu , Wan Yan , Jiang Liang-zhen , Song Chao , Xiang Da-bing
Published: September 2024

The study examined the functional properties of lactic yeast-fermented Tartary buckwheat sprout with passion and pineapple juice (Tatary buckwheat sprout juice). Pineapple and passion fruit were included during fermentation to improve the sensory and nutritional quality of the juice. We initially created a juice with Tartary buckwheat sprouts, and then fermented it with Lactobacillus plantarum and yeast (Saccharomyces cerevisiae) to produce a novel fermented sprout juice. Our results indicated that the best organoleptic quality was achieved when the inoculum of Lactobacillus plantarum was 2%, the inoculum of yeast was 1%, and the fermentation time was 30 hours. The results showed that fermentation resulted in a 1.55-fold increase in the total amino acid content, with fresh sweet amino acids increasing by 1.75-fold and sour-bitter amino acids increasing by 1.33-fold. Additionally, the levels of acetic acid, lactic acid, citric acid, and tartaric acid in the buckwheat sprout juice increased by 12.31%, 11.45%, 4.22%, and 3.88%, respectively. GC-MS analysis revealed a significant increase of volatile flavoring substances, such as alcohols and esters, by more than 24.7% in the fermentation products. From the results, yeast-Lactobacillus fermentation process may effectively improve the nutritional values of Tartary buckwheat sprout juice.
Synthesis, characterization, preliminary molecular docking, pharmacological activity, and ADME studies of some new pyrazoline derivatives as anti-breast cancer agents
Authors: Fadhil Hayder R. , Raauf Ayad M. R. , Mahdi Monther F.
Published: September 2024

This work studied the anti-breast cancer activities of pyrazoline-containing benzenesulfonamides (6–10) in vitro and silico. The GOLD suite performed molecular docking on the target human estrogen receptor and the PARPA1 antagonist crystal structure, yielding comparable results using tamoxifen as a reference drug. Researchers tested these compounds (6–10) on two types of breast cancer cells (MCF-7 and MDA-MB-468) in the lab and found an antiproliferative activity that depended on the dose. Compounds 9 demonstrated a high docking score on PARP1 antagonist crystal structure in triple-negative breast cancer with a PLP fitness score of 93.24 and potential antiproliferative activity with an IC50 of 2.79 µM on the MDA-MB-468 cell line. In contrast, compounds 8 and 10 showed promising activity on the MCF-7 cancer cell line with IC50s of 7.4 and 17.96, respectively.
Mobile Health Service Adoption: Reducing the Digital Gap and Age's Moderating Influence
Authors: B. Muruganantham  , Hezerul Abdul Karim  , Sarina Binti Mansor
Published: September 2024

In the past few years, mobile health services (MHS)—a growing topic in the healthcare sector—have received increasing attention. Technologies related to mobile health, or m-health, have several advantages for people, businesses, and medical professionals. Indeed, using m-health can help older people become more proactive patients and lessen the strain on health systems and financial resources. However, the potentially revolutionary impact of m-health is constrained since a large number of senior citizens oppose its adoption, which creates an age-based digital divide. Few studies have examined how public consumers of MHS adopt MHS, even though prior study on this topic is very substantial. We discover that user attitudes towards MHS are positively impacted by perceived benefits and usefulness, perceived barriers, and external cues. Perceived service availability also has a major impact on perceived benefits and usefulness, which, when combined with attitude, directly increases intention. Additionally, we discover that the MHS’s utilization intent has moderating effects. The final section discusses the implications for mobile health marketing. The results indicate that perceived ease of use, vulnerability, and severity are more significant factors for middle-aged and older users to use MHS. The moderator analysis confirmed that different age groups have specific moderating effects on the adoption of mobile health services.
Examining the Quality of English Online Learning Using the D&M Information System Success Model
Authors: Zhao Peng , Sun Heng
Published: September 2024

This study addresses the quality issues of university English online learning. The Delone and Mclean (D&M) information system success model (ISSM) was used to explore the impact of online platforms on students’ engagement in English learning. Empirical results indicate that both information and system quality significantly and positively predict students’ intention to use, user satisfaction, and learning engagement. However, although service quality positively influences user satisfaction, it does not reach statistical significance and has a positive impact on usage intention. Both usage intention and user satisfaction serve as mediators in the effects of both information and system quality, while only usage intention acts as a mediator in the effect of service quality on learning engagement. The mediating effect of user satisfaction does not reach significance.
A Two-Stage Robust Optimization for Reliable Logistics Network Design via Evolutionary Computation
Authors: He Junqi , Yang Dongsheng , Wang Xin
Published: September 2024

This paper presents a novel two-stage robust optimization model for designing a dependable logistics network that integrates evolutionary computation techniques. The proposed model considers both the normal and disrupted states of the logistics network and seeks to reduce the overall network cost and operating time in different disruption situations. The challenge is a multi-objective optimization problem addressed using a hybrid evolutionary method that combines the advantages of the non-dominated sorting genetic algorithm with the large neighborhood search heuristic. Numerical experiments are conducted on various test instances to demonstrate the effectiveness and efficiency of the proposed model and algorithm. The results show that the proposed algorithm can generate robust and reliable logistics network designs resilient to disruptions and uncertainties, leading to significant improvements in logistics performance and cost savings compared to traditional methods.
Outcome of tenonplasty in scleral ischemia secondary to acute ocular surface burn
Authors: Gupta Nidhi , Singh Shweta , Sangwan Virender , Mathur Umang
Published: September 2024

Purpose:

To study the outcome of tenonplasty in eyes with perilimbal ischemia in acute ocular surface burns.

Methods:

This was a single-center retrospective study that included all patients presenting between May 2012 and December 2022 with acute ocular surface burn (within 6 weeks from injury) with perilimbal scleral ischemia, without perforation or previous surgical intervention for the same. All these patients underwent single-stage tenonplasty with amniotic membrane transplantation and medical management. Successful outcome was defined as globe preservation at 6 months.

Results:

Twenty-three eyes of 20 patients were included in our study. Out of these, alkali was the most common offending agent (10 eyes of 8 patients). The extent of scleral ischemia was <90° in seven eyes, 90°–180° in six eyes, and >180° in 10 eyes. The mean interval between the injury and tenonplasty was 16.5 days. Globe integrity in 20 of the 23 eyes was maintained 6 months post injury. Three eyes that developed hypotony at the end of 6 months had more than 180° of perilimbal scleral ischemia at presentation. The extent of scleral ischemia correlated with the development of phthisis bulbi, but the values were not statistically significant (P = 0.081).

Conclusion:

Tenonplasty in the acute stage acts as a globe-salvaging procedure in acute chemical burns with perilimbal scleral ischemia. Extensive scleral ischemia in an acute chemical burn remains a poor prognostic factor for globe integrity in the long term.
Ocular biometric parameters in South-Indian children with myopia – A hospital-based retrospective descriptive analysis
Authors: Ganesh Sandra , Lusobya Rebecca Claire , Uduman Mohammed Sithiq , Rajan Reshma , Rajendran Nisha , Sanjeev Kripa , Narendran Kalpana
Published: September 2024

Aim:

This study aims to profile the ocular biometric parameters in a large group of children of South-Indian ethnicity who visited our outpatient children’s department and were diagnosed with myopia.

Methods:

Children <15 years old diagnosed with myopia (Jan 2022–Oct 2023) and who had ocular biometry readings recorded were included. Their demographics, axial length (AL), anterior chamber depth (ACD), spherical equivalent (SE), corneal radius of curvature (CR), and AL/CR ratio were analyzed.

Results:

The study included 3728 myopic children; the mean age was 11.85 (4–15) years, and 52.8% were girls. Mean SE was −3.98 D. The mean (SD) AL, ACD, CR, and AL/CR ratio were 24.64 (1.32), 3.73 (0.40), 7.61 (0.27), and 3.24 (0.16), respectively. Female gender was associated with shorter AL, ACD, CR, and AL/CR ratios (P < 0.001) across all age groups. There was a significant increase in ACD with age in both sexes (P < 0.001). A 1-unit (mm) increase in AL was associated with an SE increase of −1.65 D (CL: −1.70 to −1.60). AL/CR ratio could explain 71% of the total variance in SE (P < 0.001). SE showed a mild correlation with age (rho = 0.14, P < 0.001) and ACD (rho = −0.03, P = 0.041) and a stronger correlation with AL (rho = −0.68, P < 0.001) and AL/CR (rho = −0.83, P < 0.001).

Conclusion:

In this hospital-based study, AL and AL/CR ratios strongly correlate with SE, and the AL/CR better explains the total variance in SE than AL alone in children with myopia.
Brolucizumab in patients with neovascular age-related macular degeneration: Real-life outcomes from a tertiary care eye hospital
Authors: Fabozzi Lorenzo , Younis Saad , Sen Sagnik , López-Cuenca Inés , Palmieri Filomena
Published: September 2024

Purpose:

To report real-world clinical evidence of brolucizumab in treating neovascular age-related macular degeneration (nAMD).

Methods:

This study included 37 eyes with nAMD treated with intravitreal injections of brolucizumab. The main outcomes were best corrected visual acuity (BCVA) changes, central retinal thickness (CRT), and serious ocular adverse events. Intraretinal fluid (IRF) and subretinal fluid (SRF), subretinal hyperreflective material (SHRM), pigment epithelial detachments (PEDs), hyperreflective foci, macular atrophy, and retinal pigment epithelial tears were evaluated.

Results:

The mean BCVA of all patients showed a post-treatment value of 0.47 ± 0.33 log of minimum angle of resolution (LogMAR), compared to a baseline measure of 0.50 ± 0.28 LogMAR (P = 0.372). For treatment-naïve patients, a non-statistically significant improvement in BCVA was observed (P = 0.116). Both treatment-naive patients and the entire patient cohort exhibited a statistically significant improvement in the mean CRT after injections. Majority of patients exhibited improvements in optical coherence tomography findings, specifically in the resolution of IRF, SRF, SHRM, and PEDs. Four eyes experienced ocular adverse events in the form of intraocular inflammation.

Conclusion:

Brolucizumab did not yield a substantial improvement in BCVA, but it exhibited efficacy in reducing CRT in the entire study population and treatment-naive patients with nAMD. Our study identified intraocular inflammation as a significant adverse event with brolucizumab. Thus, precise patient selection, education, and vigilant inflammation monitoring are crucial for patients undergoing this treatment.
Inferior Turbinate Dislocation after Nasal Surgery
Authors: Alsliham Rahaf , Alotaibi Ghadah , Alrayes Nuha , Alhumaizi Abdulrahman
Published: September 2024

Nasal turbinates regulate the flow of air, but they can sometimes cause obstruction, necessitating surgical intervention. Complications such as bleeding, crustation, and scarring can occur postoperatively, and in rare instances, dislocation of inferior turbinates may occur. A 22-year-old female presented with persistent unilateral nasal obstruction following a nasal surgery. Nasal endoscopy and computed tomography revealed a nasopharyngeal mass attached to the right inferior turbinate, which was identified as a dislocated inferior turbinate due to incomplete separation during the previous surgery. Surgical excision of the dislocated inferior turbinate resolved the patient’s symptoms. Nasal obstruction can be caused by various etiologies, warranting surgical intervention. Different surgical techniques are available. Rare complications such as turbinate dislocation underscore the need for early recognition and intervention. Turbinate dislocation, although rare, should be considered a postoperative complication. Early detection leads to improved patient outcomes. Follow-up is essential for the effective management of postoperative complications.
Follicular Epithelial Dysplasia and Papillary Thyroid Carcinoma: A Retrospective Cross-sectional Study in Saudi Arabia
Authors: Hafiz Bayan Z. , Samargandy Shaza , Ajabnoor Rana , Alghamdi Doaa , Shafique Nadeem , Marzouki Hani , Merdad Mazin
Published: September 2024

Objectives:

Papillary thyroid carcinoma (PTC) is the most commonly reported thyroid malignancy. Recent epidemiological studies have demonstrated an increased risk of PTC in patients with chronic lymphocytic thyroiditis (CLT)/Hashimoto’s thyroiditis (HT). Reactive atypia is typically observed in cases of CLT/HT. If severe, this atypia is referred to as “follicular epithelial dysplasia” (FED). FED can mimic PTC; however, it lacks the invasive growth of papillary architecture and intranuclear pseudoinclusions seen in PTC. This study reviewed postthyroidectomy cases between 2016 and 2020 to evaluate the association between FED and PTC.

Materials and Methods:

A retrospective study was conducted on 91 thyroid specimens in King Abdulaziz University Hospital, Jeddah, from January 2016 to December 2020. All 91 cases have HT in addition to PTC or other benign conditions. We evaluate the level of thyroid-stimulating hormone, thyroid peroxidase antibodies (TpoAb), and thyroglobulin antibodies (TgAb) and examined the cases microscopically to evaluate: the grading of inflammation and presence of FED based on the following criteria: cells should be <1 cm, stand out on low power, and demonstrate overlapping, crowding, irregular nuclear membranes, and mild grooves on high power.

Results:

HT was most frequently observed in female patients (93.4%). Almost 60% of the participants were aged over 40 years. Nearly half of the samples were euthyroid (51.2%), with high levels of preoperative TgAb and TpoAb observed in 83% and 72.9% of participants, respectively. No significant association was observed between FED and PTC (P = 0.39). Similarly, inflammation grade was also not found to be associated with PTC (P = 0.98).

Conclusion:

FED is a challenging diagnosis, and additional research is required to understand its nature and determine whether or not it should be classified as premalignant. Obtaining a second opinion from a subspecialized pathologist is highly recommended when encountering suspected FED.
TERT mutations and aggressive histopathologic characteristics of radioiodine-refractory papillary thyroid cancer
Authors: Pyo Ju Yeon , Cha Yoon Jin , Hong SoonWon
Published: September 2024

Background: Radioiodine (RI) ablation following thyroid-stimulating hormone suppression is an effective treatment for papillary thyroid cancer (PTC), typically leading to favorable outcomes. However, RI-refractory tumors exhibit aggressive behavior and poor prognoses. Recent studies highlight the role of genetic abnormalities in PTC signaling pathways, including the activation of telomerase reverse transcriptase (TERT), and the correlation of mutations with adverse outcomes. Methods: This study analyzed mutations in BRAF V600E and the TERT-promoter genes, comparing clinicopathological features between RI-refractory and RI-responsive PTCs. Among 82 RI-refractory patients, formalin-fixed, paraffin-embedded tissues from initial surgeries were available for 26. Another 89 without distant metastasis over 5 years formed a matched RI-responsive control group. Results: Histopathologically, RI-refractory PTCs showed increased frequencies of small tumor clusters without fibrovascular cores, hobnail features, and a high height-to-width ratio of tumor cells. These tumors were more likely to exhibit necrosis, mitosis, lymph node metastasis, extrathyroidal extension, and involvement of resection margins. TERT-promoter mutations were statistically significantly associated with these aggressive clinicopathologic features. Immunohistochemically, decreased expression of sodium iodide symporter and thyroglobulin stimulating hormone receptor proteins was common in RI-refractory PTCs, along with lower levels of oncogenic proteins such as vascular endothelial cell growth factor, vascular endothelial cell growth factor receptor 2, and nuclear factor kappa-light-chain-enhancer of activated B cells. Total loss of PTEN expression was occasionally observed. In contrast, all cases tested positive for cytoplasmic β-catenin. Conclusions: RI-refractory PTCs are linked to TERT mutations and exhibit specific aggressive histopathologic features, particularly in tumor centers.
Histopathologic classification and immunohistochemical features of papillary renal neoplasm with potential therapeutic targets
Authors: Park Jeong Hwan , Shin Su-Jin , Kim Hyun-Jung , Oh Sohee , Cho Yong Mee
Published: September 2024

Background: Papillary renal cell carcinoma (pRCC) is the second most common histological subtype of renal cell carcinoma and is considered a morphologically and molecularly heterogeneous tumor. Accurate classification and assessment of the immunohistochemical features of possible therapeutic targets are needed for precise patient care. We aimed to evaluate immunohistochemical features and possible therapeutic targets of papillary renal neoplasms Methods: We collected 140 papillary renal neoplasms from three different hospitals and conducted immunohistochemical studies on tissue microarray slides. We performed succinate dehydrogenase B, fumarate hydratase, and transcription factor E3 immunohistochemical studies for differential diagnosis and re-classified five cases (3.6%) of papillary renal neoplasms. In addition, we conducted c-MET, p16, c-Myc, Ki-67, p53, and stimulator of interferon genes (STING) immunohistochemical studies to evaluate their pathogenesis and value for therapeutic targets. Results: We found that c-MET expression was more common in pRCC (classic) (p = .021) among papillary renal neoplasms and Ki-67 proliferation index was higher in pRCC (not otherwise specified, NOS) compared to that of pRCC (classic) and papillary neoplasm with reverse polarity (marginal significance, p = .080). Small subsets of cases with p16 block positivity (4.5%) (pRCC [NOS] only) and c-Myc expression (7.1%) (pRCC [classic] only) were found. Also, there were some cases showing STING expression and those cases were associated with increased Ki-67 proliferation index (marginal significance, p = .063). Conclusions: Our findings suggested that there are subsets of pRCC with c-MET, p16, c-MYC, and STING expression and those cases could be potential candidates for targeted therapy.
A climate-fiscal policy mix to achieve Türkiye’s net-zero ambition under feasibility constraints
Authors: Schoder Christian , Tercioglu Remzi Baris
Published: September 2024

This paper employs an estimated dynamic stochastic open-economy macro framework to identify policy interventions that allow Türkiye to achieve net-zero emissions by 2053 while respecting important feasibility constraints such as fiscal consolidation and sovereign debt stability as well as compensation of low-income households. The policy mix includes a carbon tax, a renewable energy subsidy, transfer payments, public infrastructure investments, a bad bank for stranded fossil fuel assets, and the phase-out of fossil fuel subsidies and public investment. Although the proposed policy package has only moderate effects on gross domestic product, transition risks involve declining exports and fossil asset stranding. The paper highlights the importance of transparent policy communication and a credible commitment to the net-zero agenda to ensure an orderly transition. Improving the rule of law and access to green finance considerably support the private sector-led low-carbon transition.
Czynniki ryzyka otyłości wśród pracowników fizycznych
Authors: Łastowiecka-Moras Elżbieta
Published: September 2024

The problem of obesity not only affects people working in various sectors and performing various professions but also affects the work environment. Blue-collar workers, even though their work involves physical exertion, may also be exposed to problems with maintaining proper body weight. The work environment can directly influence employee’s lifestyle behaviours. An active lifestyle related to professional work that is not adapted to the employee’s capabilities often leads to fatigue and may be the reason for reluctance to engage in recreational activities. Performing physical work may also lead to various types of health problems that contribute to limiting physical activity, both in professional and recreational sense. Excess work and responsibilities often force employees to limit their daily meals to a minimum. Additionally, certain factors present in the work environment may also increase the risk of developing obesity. These include, among others: shift work, certain chemical factors, employment conditions, and psychosocial working conditions.
Zaskarżalność rozstrzygnięcia o zwrocie zobowiązanemu kosztów egzekucyjnych w postępowaniu egzekucyjnym w administracji
Authors: Majer Tomasz Tadeusz
Published: September 2024

One of the consequences of entering the Act of July 4, 2019, amending the Act on enforcement proceedings in administration and certain other acts into force, was the supplementation of the Act of June 17, 1966, on enforcement proceedings in administration with Art. 64cd. The new provision was an extension of the previous regulation contained in Art. 64c § 3 of the Act on the possibility of reimbursement of enforcement costs. This regulation also covered the procedure for appealing against a decision on reimbursing enforcement costs to the obligated party. It also specifies the principles for appealing against a separate decision on charging a creditor with enforcement costs reimbursed to the obligated party. The wording of the provision may raise doubts regarding the determination of the circle of entities that may challenge decisions on the reimbursement of enforcement costs to the obligated party.

The purpose of this article was, first of all, to discuss the current procedure for reimbursement of enforcement costs, as well as to demonstrate the linguistic interpretation of Art. 64cd of the Act on Enforcement Procedure. The author put forward the thesis that in the case of a decision to refund or refuse to refund the costs of enforcement proceedings. Although the legislator did not limit the category of entities entitled to file a complaint, this right may only be assigned to the beneficiary of the refund, the obligated party or the creditor, respectively.
Zmiany w przepisach o karach pieniężnych za niepowiadomienie o zbyciu lub nabyciu pojazdu jako przykład niedopracowanej legislacji
Authors: Szafrańska Weronika
Published: September 2024

On January 1, 2024, the long-awaited changes to the Road Traffic Law came into force, imposing administrative fines on vehicle owners (former owners) for failure to notify about their purchase or sale. The penalty for failure to notify about the purchase of a vehicle has been replaced in the abovementioned regulations with a penalty for failure to register it. The penalty rates have also changed, and the obligation for co-owners to bear the penalty jointly and severally has been introduced. The legislator has also excluded the possibility of applying general provisions on penalties from Chapter IVA of the Polish Code of Administrative Procedure, including the possibility of waiving the imposition of a penalty. Although some of the changes should be assessed positively, some errors were highlighted in this article.