bluuebunny/crossref_metadata_2025 huggingface dataset:
Сравнительный анализ методов количественного определения производного индолокарбазола ЛХС-1269 в лекарственной форме
Authors: Шпрах Зоя Сергеевна , Игнатьева Елена Владимировна , Козин Дмитрий Андреевич , Ланцова Анна Владимировна , Николаева Людмила Леонидовна , Васильевич Гусев Дмитрий
Published: December 2024

В ФГБУ «НМИЦ онкологии им. Н. Н. Блохина синтезировано оригинальное химическое соединение из класса N-гликозидов индоло[2,3-a]карбазолов (ЛХС-1269) с выраженной противоопухолевой активностью, и получена его лекарственная форма для инъекционного введения. Для количественной оценки ЛХС-1269 в лекарственной форме разработаны методики спектрофотометрического и хроматографического определения. Сравнительный анализ валидационных характеристик двух методик показал, что они специфичны, линейны, свободны от систематических ошибок, не отличаются по прецизионности и могут быть использованы для количественного определения ЛХС-1269 в лекарственной форме. Метод ВЭЖХ предпочтительнее, поскольку пределы обнаружения и количественного определения ВЭЖХ-методики более чем в 100 раз ниже, чем для метода спектрофотометрии.
Кинетика транскутанной диффузии дезлоратадина из матричных пластырей
Authors: Агеев Валентин Павлович , Заборовский Андрей Владимирович , Тарарина Лариса Анатольевна , Юнина Дина Владимировна , Фоменко Алексей Константинович , Куркин Денис Васильевич , Пьянзина Александра Евгеньевна , Шляпкина Василиса Игоревна , Гололобова Ирина Александровна , Куликов Олег Александрович , Пятаев Николай Анатольевич
Published: December 2024

Цель работы — изучение кинетики транскутанной диффузии дезлоратадина из матричных пластырей двух типов, содержащих действующее вещество в ионной и наноструктурированной формах (в виде мицелл на основе твина-80). Исследование включало оценку эффективности транспорта дезлоратадина через целлюлозную мембрану и через кожу крыс с помощью диффузионных ячеек Франца. Количественное определение дезлоратадина и компонентов пластырей проводили с помощью УФ-спектрометрии. Результаты показали, что матричные пластыри, содержащие дезлоратадин в мицеллярной форме, обеспечивают более полное и продолжительное высвобождение действующего вещества в экспериментах с кожей крыс, что подтверждает их потенциал для использования в качестве эффективной формы транскутанной доставки данного лекарственного вещества.
Неинтервенционное многоцентровое проспективное исследование эффективности циклоферона (меглюмина акридонацетат) у пациентов с ОРВИ на амбулаторном этапе в период 2023 – 2024 гг.
Authors: Агафьина А. С. , Альпенидзе Д. Н. , Василюк В. Б. , Егорова Н. В. , Русанова Е. И. , Обрезан А. Г. , Пак Т. Е. , Сардинов Р. Т. , Свеклина Т. С.
Published: December 2024

Проведена оценка эффективности и безопасности Циклоферона (меглюмина акридонацетат) у взрослых пациентов с ОРВИ. Пострегистрационное многоцентровое проспективное неинтервенционное исследование было проведено на базе 15 учреждений Санкт-Петербурга и Москвы с участием 742 пациентов мужского и женского пола в амбулаторных условиях. В исследовании было предусмотрено 4 визита в клинический центр: на 1, 3, 5 и 9 дни, 1-й визит совпадал с началом применения препарата. Все пациенты получали Циклоферон по 600 мг (в таблетках) на 1, 2, 4, 6 и 8 сут, либо умифеновир по 200 мг 4 раза в сутки (в капсулах) в течение 5 дней. Назначение противовирусных лекарственных средств осуществляли согласно утвержденной инструкции по медицинскому применению и установившейся клинической практике медицинского учреждения, после чего пациенты были распределены на 2 группы. Из включенных участников завершили исследование без значительных отклонений от протокола и имели достаточную комплаентность 676 пациентов. В группу Циклоферона было включено 316 пациентов, в группу умифеновира — 360 пациентов. Всем пациентам на скрининге выполнялась ПЦР-диагностика мазка из носо- и ротоглотки. Эффективность оценивали по длительности гипертермии, выраженности симптомов по шкалам WURSS-21, CCQ, продолжительности периода временной нетрудоспособности и необходимости назначения антибактериальной терапии. Результаты проведенного исследования показали преимущество базовой терапии ОРВИ c Циклофероном по сравнению с умифеновиром у амбулаторных пациентов с ОРВИ, при сопоставимо высоких показателях безопасности. Продолжительность гипертермии различалась между группами исследования в пользу Циклоферона (3,66 дня в группе Циклоферона, 4,06 дня — в группе умифеновира, p = 0,01). Профиль тяжести симптомов, оцененный с помощью площади под кривой для суммы баллов по опроснику WURSS-21, за 2, 3 и 4 визиты различался между группами исследования, в группе Циклоферона составил 34,69 ± 21,74, в группе сравнения — 41,49 ± 29,93 (p = 0,035). Изменение общего балла CCQ на каждом визите было значимо ниже (p < 0,001) относительно визита 1 в обеих группах. Выраженность симптомов по шкале CCQ была ниже в группе Циклоферона на всех визитах (p < 0,05). Средняя длительность периода временной нетрудоспособности была меньше в группе Циклоферона (медианное значение 5 и 7 дней, соответственно, p < 0,001). В исследовании был установлен сопоставимо высокий профиль безопасности «исследуемых препаратов».
Лечение первично-множественных злокачественных опухолей: муцинозной аденокарциномы яичников и аденокарциномы головки поджелудочной железы (клиническое наблюдение)
Authors: Скокова Оксана Сергеевна , Малицкий Н. А. , Чехова А. И. , Канкалов Г. П. , Давыдова С. М. , Овчаренко К. Г. , Оголь М. И. , Гулян А. А. , Бочка К. А.
Published: December 2024

В 1947 г. Н. Н. Петров сформулировал определение первично-множественных злокачественных опухолей (ПМЗО), которые по сей день представляют собой малоизученную проблему в современной онкологии. Одним из основных критериев ПМЗО является установление их первичности, что подразумевает под собой исключение гематогенного, лимфогенного метастазирования, а также контактного распространения опухолевого процесса. В последние годы отмечено увеличение частоты множественных новообразований. В данной статье представлено клиническое наблюдение лечения первично-множественных злокачественных метахронных опухолей: муцинозной аденокарциномы яичников и аденокарциномы головки поджелудочной железы спустя 12 мес после лечения первой опухоли.
Доклиническое изучение безопасности коллагеназы из африканского сома Clarias gariepinus
Authors: Саватеева-Любимова Тантьяна Н. , Сивак Константин В. , Стосман Кира И. , Калинина Елена Ю. , Казакова Светлана Б. , Оршанская Яна Р. , Любишин Михаил М. , Федорова Виктория А. , Парамонов Борис А. , Скворцов Никита В. , Пожарская Елена М.
Published: December 2024

В рамках доклинического исследования проведено изучение безопасности протеолитического средства «Коллагеназа» из африканского сома Clarias gariepinus. Изучена токсичность при одно- и многократном введении на двух видах животных (крысы и кролики обоего пола), иммунотоксичность, аллергизирующие свойства, репродуктивная токсичность и мутагенная активность. Показано отсутствие летальности при однократном внутрижелудочном введении коллагеназы крысам в максимально возможной дозе. В условиях многократной, в течение 30 дней, накожной аппликации на выстриженную и частично скарифицированную кожу спины крыс и кроликов обоего пола наблюдали повышение двигательной и ориентировочной реакции в тесте «Открытое поле» у крыс обоего пола. Данные изменения носили обратимый характер. У самцов крыс, получавших коллагеназу внутрижелудочно в дозе 0,34 мг/кг, и у самок (3,4 мг/кг), наблюдали повышенный уровень диуреза, а также несколько сниженный (по отношению к плацебо) рН только у самцов (p < 0,05). Выявленные статистически значимые изменения показателей не выходили за пределы диапазона нормы для крыс. Местно-раздражающее действие не выявлено. Коллагеназа в исследованных дозах не обладала иммунотоксическими, эмбриотоксическими, генотоксическими и аллергизирующими свойствами и не влияла на генеративную функцию.
История внедрения антипсихотических средств в зарубежную психиатрическую практику
Authors: Демьянов Глеб Валерьевич , Лихтерман Болеслав Леонидович
Published: December 2024

Современная фармакотерапия психических заболеваний, ведущая свою историю с введения в клиническую практику в 1952 г. антипсихотического средства аминазина (хлорпромазина), возникнув во Франции, стремительно распространилась по всему миру. Началась новая эпоха в лечении психических заболеваний, неотделимая от развития психофармакологии — раздела фармакологии, занимающегося созданием психотропных средств и изучением их механизмов действия. Описывая смену одних антипсихотических средств другими, авторы литературного обзора определяют аспекты внедрения данных психотропных средств в клиническую практику западноевропейских стран и США с 1950-х по 2000-е гг., анализируют проблемы, с которыми сталкивалась в своем распространении и общемировом признании терапия антипсихотическими средствами, обозначают особенности фармакологических исследований механизмов действия антипсихотических средств.
Действие производных 1,2,3,4-тетрагидроизохинолиновых алкалоидов на NMDA-рецепторы, холинэстеразы и оценка их антиоксидантной и противосудорожной активности в эксперименте
Authors: Махаева Галина Файвелевна , Азаматов Азиз Азамат угли , Турсунходжаева Фируза Муратовна , Журакулов Шерзод Нияткабулович , Григорьев Владимир Викторович , Ковалева Надежда Владимировна , Рудакова Елена Владимировна , Габрельян Алексей Витальевич , Виноградова Валентина Ивановна , Шевцова Елена Феофановна , Сагдуллаев Шамансур Шахсаидович , Бачурин Сергей Олегович
Published: December 2024

Для ряда производных 1,2,3,4-тетрагидроизохинолинов изучены: 1) влияние на связывание [3H]MK-801 и [3H]ифенпродила с NMDA-рецепторами фракции синаптических мембран из головного мозга крыс, 2) ингибирование активности ацетилхолин- эстеразы, бутирилхолинэстеразы и карбоксилэстеразы, 3) антиоксидантная активность и 4) противосудорожная активность на модели никотиновых судорог у мышей. Установлено, что большинство соединений блокирует внутриканальный сайт связывания NMDA-рецепторов с максимальной активностью у соединений 6 с 2-Br-фенильным заместителем (ИК50 = 10,4 ± 0,6 мкМ) и 4 с 2-нитрофенильным заместителем (ИК50 = 12,7 ± 0,5 мкМ), соединения 6 и 11 блокируют аллостерический сайт NMDA-рецептора (ИК50 = 72,8 ± 7,7 и 25,2 ± 2,9 мкМ соответственно). Обнаружено, что соединение 11, 2-((6-бромбензо[d][1,3]диоксол-5-ил)метил)-6,7-диметокси-1,2,3,4-тетрагидроизохинолин, одновременно селективно ингибирует бутирилхолинэстеразу (ИК50 = 29,8 ± 1,2 мкМ) и блокирует аллостерический сайт NMDA-рецептора; также найдены соединения со значительным антиоксидантным (соединение 8, TEAC = 1,7) и высоким противосудорожным (соединения 7, 8, 9) потенциалом.
Análisis de la propuesta didáctica “The Rape of Lucrece”
Authors: Latorre Elena Lilian , Cazorla María Angelina
Published: December 2024

Este análisis descriptivo se concentra en las acciones superadoras de las dificultades de lectura comprensiva y criticidad de los estudiantes de educación superior y examina una propuesta diseñada en el marco de la cátedra Culturas IV del profesorado en lengua-cultura inglesa. El análisis se sustenta en la premisa de la lectura y la escritura como prácticas necesarias para potenciar el pensamiento crítico promovidas a través de acciones de enseñanza ajustadas a diferentes momentos de práctica y objetivos de aprendizajes esperados. La propuesta didáctica analizada está basada en tres elementos fundamentales: (1) el hecho histórico protagonizado por la joven romana Lucrecia en el siglo VI a.C., (2) el poema narrativo histórico The Rape of Lucrece, de William Shakespeare, y (3) las expresiones filosóficas de San Agustín de Hipona en torno al caso histórico. La iniciativa didáctica incluye la indagación de situaciones problemáticas similares en la actualidad y el análisis comparativo o contrastivo entre la situación actual y el caso histórico-literario de la joven latina.
La finalidad de esta descripción es el registro exhaustivo de las acciones de enseñanza relacionadas con los momentos de práctica organizados y los objetivos esperados en los aprendizajes de los estudiantes. Como el propósito del estudio realizado no es evaluar producciones de los estudiantes, sino describir las acciones docentes, las conclusiones obtenidas indican que la comprensión lectora y el pensamiento crítico fueron orientados por acciones de desarrolladas en función de momentos de práctica y objetivos de aprendizaje.
Taller de atletismo escolar en la EESO 391 “Dr. Agustín Zapata Gollán” de la ciudad de Santa Fe, Argentina. Hacia prácticas deportivas coeducativas en la escuela secundaria. Tesis de Maestría en Educación Física y Deporte, Universidad Nacional de Avellaneda (Argentina).
Authors: Rodríguez Piñero Cristian David
Published: December 2024

Tesis de Maestría en Educación Física y Deporte, Universidad Nacional de Avellaneda (Argentina).
La gestión educativa de la escuela secundaria: aportes desde la perspectiva de directivos de la provincia de Buenos Aires, entre 2010 y 2020
Authors: Asprella Gabriel , Vicente María Eugenia
Published: December 2024

En la escuela secundaria de Argentina, y en particular en la Provincia de Buenos Aires, conviven escenarios de cambio y hasta cierta mutación que hacen posible analizar las condiciones en que se desarrolla la acción directiva. Nos hallamos ante una realidad que habilita el análisis sobre cómo los directivos escolares de secundaria, en medio de las condiciones cotidianas, afrontan a diario la gestión del sistema educativo. En este sentido, el artículo tiene el objetivo de identificar concepciones y representaciones que caracterizan el pensamiento de directivos de escuelas de educación secundaria de la Provincia de Buenos Aires sobre gestión educativa y sus modelos subyacentes. Se presentan los resultados de dos investigaciones culminadas. Metodológicamente, se trabajó con entrevistas en profundidad a directivos de la Provincia de Buenos Aires, realizadas entre los años 2010 a 2020. Las dimensiones de análisis sobre las que versan los resultados son: las impresiones sobre la gestión de la escuela secundaria obligatoria; los intereses y prioridades en la agenda cotidiana; y el reconocimiento de conflictos en la gestión educativa. Las conclusiones se orientan a contribuir a la comprensión de la dinámica y la estructura social que se expresa en el espacio escolar y la connotación que eso tiene para la planificación política e institucional.
Pengaruh Penggunaan Youtube Sebagai Media Pembelajaran Terhadap Tingkat Kreativitas Mahasiswa Ekonomi Di Universitas Negeri Medan
Authors: Siboro Hotman , Pasaribu Nurita , Hutahaean Rahel , Situmorang Eva , Haryadi Haryadi
Published: December 2024

This study aims to analyze the impact of using YouTube as a learning medium on the creativity levels of economics students at Universitas Negeri Medan. In the digital era, YouTube has become a popular educational resource, offering diverse content that supports the learning process. Creativity is an essential competency for students to face challenges in a competitive business world. This research employs a survey method, collecting data through questionnaires distributed to students. Quantitative data analysis is conducted to identify the relationship between YouTube usage and creativity levels. The findings indicate that, although YouTube provides access to various information, no significant impact on enhancing student creativity was found. This highlights the need for active engagement in the learning process to stimulate creativity and provides recommendations for the development of more interactive and collaborative teaching methods. This research is expected to contribute to the advancement of higher education in Indonesia.
Analisis Kinerja Operator Sekolah Yang Dipengaruhi Oleh Penguasaan Teknologi, Fasilitas dan Kesejahteraan
Authors: Sriyanti Esi , Roza Seflidiana , Maharani Anita
Published: December 2024

Supaya amanah serta tanggung jawab bisa terpenuhi dengan efektif, operator sekolah wajib mengetahui serta memiliki keterampilan dalam mengelola Data Pokok Pendidikan. Dilakukannya studi ini bertujuan agar dapat diketahui pengaruh daripada penguasaan teknologi, fasilitas, dan kesejahteraan yang akan memberikan dampak kepada kinerja operator di SD Negeri se Kota Solok. Penelitian kuantitatif ini menggunakan pendekatan deskriptif. Data yang dipakai asalnya dari data awal yang diperoleh dari kuesioner yang dibagikan ke peserta atau responden yang dalam hal ini operator sekolah. Studi ini melibatkan seluruh operator di SDN se Kota Solok, yang berjumlah 41 orang, yang diambil sampel secara keseluruhan. Maka itu, sampel di studi ini sebanyak 41 orang. Adapun analisis data dilaksanakan dengan memakai uji instrumen, analisis regresi linier berganda, uji hipotesis, serta uji koefisien determinasi. Dari hasil uji yang dilakukan, memperlihatkan bahwasanya variabel Penguasaan Teknologi (X1), Fasilitas (X2) dan Kesejahteraan (X3) secara parsial berdampak positif terhadap Kinerja Operator Sekolah (Y) Dasar Negeri Se Kota Solok. Selanjutnya, berdasarkan koefisien determinasi 0,690, terbukti bahwasanya variabel Penguasaan Teknologi (X1), Fasilitas (X2) dan Kesejahteraan (X3) secara simultan berdampak positif terhadap Kinerja Operator Sekolah (Y).
Implementasi Manajemen Berbasis Sekolah Dalam Meningkatkan Mutu Pendidikan di SMA N 1 Jepon Blora
Authors: Listyari Farida , Haryati Titik , Wuryandini Endang
Published: December 2024

Penelitian ini bertujuan untuk menganalisis implementasi Manajemen Mutu Berbasis Sekolah (MBS) dalam meningkatkan mutu pendidikan di SMA N 1 Jepon Blora. Pendekatan kualitatif deskriptif digunakan untuk memahami secara mendalam peran kepala sekolah, wakil kepala sekolah, guru, siswa, komite sekolah, dan orang tua dalam penerapan MBS. Data dikumpulkan melalui wawancara mendalam, observasi partisipatif, dan studi dokumentasi, yang dianalisis secara tematik. Hasil penelitian menunjukkan bahwa kepala sekolah berperan sebagai pemimpin strategis yang menggerakkan seluruh komponen sekolah, didukung oleh peran wakil kepala sekolah bidang kurikulum dan kesiswaan dalam mengelola program pembelajaran dan pengembangan siswa. Guru terlibat aktif dalam inovasi pembelajaran, sementara komite sekolah dan orang tua memberikan dukungan signifikan dalam perencanaan dan pengelolaan sekolah. Kendala utama dalam implementasi MBS adalah keterbatasan anggaran, rendahnya pelatihan teknologi bagi guru, dan partisipasi masyarakat yang belum optimal. Penelitian ini menyimpulkan bahwa kolaborasi intensif antara semua pemangku kepentingan diperlukan untuk mengatasi tantangan tersebut dan mencapai mutu pendidikan yang lebih baik
Analisis Faktor-Faktor Yang Mempengaruhi Minat Belajar Tata Rias Dalam Kegiatan Ekstrakurikuler Beauty Class Pada Siswi SMA Berkebutuhuan Khusus Di SLB 02 Lenteng Agung Jakarta Selatan
Authors: Youdhiyan Maritie Aprilia , Yulia Elvyra , Atmanto Dwi
Published: December 2024

The purpose of the study is to analyze the factors that affect the interest in learning cosmetology in beauty class activities in high school students with special needs at SLBN 02 Lenteng Agung South Jakarta, This study is a quantitative research with the results of a hypothesis between variables X (factors that affect learning interest) and Y (interest in learning cosmetology) obtained the results of the t-test has a hypothesis test result which shows a significance value of 0.001 i.e. ≤ 0.05 shows that Ho is rejected and Ha is accepted, which means that there is a significant positive influence between factors that affect learning interest in cosmetology. The result of the determination coefficient (R2) is 0.953 which means that learning interest factors play a role of 95.3% in the interest in learning cosmetology. The remaining 4.7% was influenced by other variables that were not studied in this study. The results of this study concluded that the indicator that got the highest score from the X variable (factors that affect learning interest) was the "attention" indicator of 23.31% and from the Y variable (interest in learning cosmetology) got the highest score, namely the indicator of "general attitude towards activities" of 39.23%.
Pelatihan Kegiatan Membuat Keterampilan Mozaik Dengan Palawija Untuk Meningkatkan Kreativitas Siswa Kelas V SDN 104277 Desa Tanah Merah
Authors: Harahap Juli Yanti , Friska Diva , Wangi Indah Sekar , Kumala Sari Siti Asnik , Anjani Yulia , Abidah Hania
Published: December 2024

Community Service with the title "Training in Activities for Making Mosaic Skills with Secondary Education to Increase the Creativity of Class V Students at SDN 104277 Tanah Merah Village" aims to increase students' creativity in making skills in the form of mosaics. The method used in community service activities is through the lecture method and providing training to class V students at SDN 104277 Tanah Merah Village. This activity begins by providing tools and materials for mosaics using secondary crops such as peanuts, corn, green beans and rice. The results achieved from this mosaic training activity were that almost all students were able to increase their creativity in mosaic making skills and they were also able to make wall decorations using mosaic techniques.
Pemanfaatan Augmented Reality (AR) Sebagai Media Pembelajaran Benda Padat, Cair dan Gas
Authors: Simaremare Togihon J.P. , Emi Yuliana , Bahari Yohanes , Warneri Warneri
Published: December 2024

The rapid development of technology encourages the diffusion of innovation in the world of education, including in learning methods. One phenomenon of innovation that is used and continues to increase is the use of Augmented Reality (AR) media as an interactive learning media. The purpose of this study is to measure the effectiveness of AR learning media and student responses after using the learning media. This research uses quantitative descriptive method. AR learning media will be tested on 18 third grade students of SD Tunas Bangsa Kubu Raya, which is divided into four groups. The instruments used are questionnaires to measure students' responses and post-test to evaluate students' knowledge improvement after using AR learning media. In conclusion, by using AR media in learning material about solid, liquid and gas objects, students showed a significant increase in understanding when doing the post-test. Students are able to understand that solid objects do not necessarily have to be hard, but have other characteristics that distinguish them from liquid and gas substances. The results of the student response questionnaire to AR learning media are 82.2% with a very good response category.
Kajian Strategi Manajemen Kesiswaan untuk Meningkatkan Kualitas Pendidikan di Sekolah Menengah Kejuruan
Authors: Yosiana Angela , Ernawati Ernawati , Mardiza Jonni
Published: December 2024

This study aims to examine effective student management strategies in improving the quality of education in Vocational High Schools (SMK). Student management plays an important role in creating a conducive educational environment, which has a direct impact on students' academic success and character development. Through the Systematic Literature Review (SLR) approach, this study collects and analyzes previous studies that discuss the relationship between student management and the quality of education in SMK. The results of the study indicate that student management strategies, such as managing extracurricular activities, character building, and student supervision and motivation, can significantly improve the quality of education in SMK. This study provides insights for SMK managers and policy makers to optimize student management in order to create higher quality education that is relevant to industry needs.
Pengaruh Media Panorama dan Wordwall dalam Pembelajaran Pendidikan Pancasila Terhadap Minat Belajar Peserta Didik Kelas V SDN Pulorejo 01
Authors: Diah Utami Afitri , Tri Rahayu Erviana , Widodo Susilo Tri , Nuraeni Rina , Wulandari Esti
Published: December 2024

Someone who has an interest will be stimulated to be enthusiastic about an activity, including studying. Students' learning interest can be influenced by the learning media implemented by the teacher during the learning process. This research aims to determine the effect of using panorama and Wordwall learning media and compare the effectiveness of the two media in learning Pancasila Education on the learning interest of class V students at SDN Pulorejo 01. This research uses the Classroom Action Research method. The data analysis technique used in this research is descriptive qualitative.  From the teaching practice activities that have been carried out by the author by applying panorama and wordwall media in Pancasila education learning in class V at SDN Pulorejo 01, it can be seen that these two media have an influence on the learning interest of class V students at SDN Pulorejo 01. The students were initially passive and less active becomes more active after using learning media in teaching and learning activities. Based on the research that has been carried out, the most effective way to apply Pancasila education for class V at SDN Pulorejo 01 is wordwall.
The Use of Youtube to Improve Listening Skills for Non-English Major Students in EFL Classroom
Authors: Juita Erlinna
Published: December 2024

Compared to the four language skills, listening is the first language skill acquired by a language learner. Nevertheless, Students frequently had low performance in listening. They also had a notion that listening can be hardly acquired. Thus, new methods need to applied in listening activities, one of them is using YouTube. This study is classroom action research conducted in two cycles. The subjects of this study were 49 students of Akademi Kesehatan John Paul II Pekanbaru. Tests and Interviews were carried out to collect data. In cycle 1, the students’ score increased from 50 to 65.10. In cycle 2, the students obtained the average score of 71.02. In conclusion, the use of YouTube in listening activities can improve students’ listening skills. The result of interview revealed that students are more interested in learning English through YouTube. They can learn pronunciation and how to express ideas the same way native speakers did.
Penempatan, Pengembangan Karier dan Kesejahteraan Karyawan di MA PP Darussalam Kasomalang
Authors: Badrudin Muhamad Badar , Hidayat Wahyu
Published: December 2024

This study aims to analyse the practices of placement, career development and employee welfare at MA PP Darussalam Kasomalang, and to examine their impact on work effectiveness and the quality of the organisational environment. Using a qualitative approach with a case study method, this research involved educators, administrative staff, and management as research subjects. Data were obtained through in-depth interviews, direct observation, and document analysis, then analysed thematically to identify relevant patterns. The results showed that employee placement based on a match between individual competencies and organisational needs contributed to increased productivity and job satisfaction. The career development programme implemented, although still limited, is able to encourage employee motivation and loyalty. Meanwhile, employee well-being, which includes physical, psychological and work-life balance aspects, plays an important role in maintaining retention and creating a harmonious working environment. The relationship between placement, career development and employee welfare proved significant in supporting the achievement of the institution's overall goals. This research makes a practical contribution to human resource management in educational institutions by recommending more structured strategies in employee placement, provision of comprehensive career development programmes, and improved welfare policies.
Analisis Strategi Pemasaran pada PT Astra Internasional Tbk
Authors: Oktavia Shintami , Simanjuntak Hasiandra , Sandrina Sitompul Putri , Narwastu Radhika , Martiza Sari Maya , Miranda Lumbangaol Cecilia , M.C Sinulingga Dicky
Published: December 2024

Information within a company is very important to support sustainability development, so there is a reason that information is really needed for a company company. One company that uses an integrated information system network to make business easier the company is PT. Telkom . Telkom demands to be even better improve the quality and quantity of its services in order to become a company the best telecommunications in Indonesia and even the world, not only that, PT Telkom too Realizing that there is the importance of human resources (HR) in helping company to achieve its main targets, and in helping the company to achieve main target, and in its implementation must take into account social interests, functional and employee.
Pengaruh Literasi Keuangan terhadap Nilai Konsumtif Mahasiswa Pendidikan Ekonomi 2022
Authors: Siagian Irma , Hutasuhut Saidun , Larasati Sinaga Dewi , Ulinda Tinambunan Fitry , Lylia Saragi Sarah , Sitio Veranita , Valentina Banjar Yefoni
Published: December 2024

This research aims to analyze the influence of financial literacy on the consumptive behavior of students in the Economic Education Study Program, Medan State University class of 2022. The research uses a correlational quantitative approach with survey methods. Data was collected through a Likert scale-based questionnaire that measures financial literacy and consumer behavior. The results show that financial literacy has a significant influence on student consumptive behavior with a coefficient of determination (R²) of 38.3%. Students with a higher level of financial literacy tend to be wiser in managing their finances, so they are able to suppress consumer behavior. This research emphasizes the importance of financial literacy education as an effort to increase students’ financial awareness to support their financial independence in the future.
Etnomatematika: Identifikasi Unsur Matematis pada Struktur Utama Bangunan Candi Tikus Kabupaten Mojokerto
Authors: Sugandi Eko , Maftuh Syukron , Prayitno Lydia Lia , Mutianingsih Ninik
Published: December 2024

This research to show the relationship between mathematics and the structure of the Tikus Temple building, Mojokerto Regency. This research aims to explore parts of Tikus Temple that contain mathematical concepts. The building structure is the focus of this research. The method used in this study uses ethnographic methods with data collection techniques using ethnographic principles such as observation, interviews, documentation, and making field notes. The results showed that ethnomathematics exploration of the structures of the Tikus Temple contains cultural values full of history and mathematical concepts in the material of geometric transformations, plane shapes, and spatial shapes.
Pengaruh Media Pembelajaran Kincir Pintar Terhadap Kemampuan Keaksaraan Awal Anak Usia 5-6 Tahun di TK Santo Thomas 1 Medan
Authors: Munawwarah S Hidayatul , Farida Niken , Rosalina Duha Delfi
Published: December 2024

This research aims to determine the effect of smart wheel learning media on the early literacy abilities of children aged 5 - 6 years at Santo Thomas 1 Medan Kindergarten. This type of research is quantitative research with a quasi-experimental research design. The sample selection technique used was random sampling. The sample in this study was all children aged 5 - 6 years at Kindergarten Santo Thomas 1 Medan, totaling 44 children who were combined into two groups, namely the experimental class and the control class. This research was analyzed using SPSS 22 with the normality test, homogeneity test, and hypothesis testing using the t test. Based on the results of research data analysis, it was found that the average value of the pretest and posttest, namely 10.61, increased to 16.17 and the results of the t test sample hypothesis test were sig (2-tailed) with pretest and posttest of 0.005 <0.05. The results of the t test analysis show that the value of t count > t table (2.955 > 1.68195) means that Ho is rejected and Ha is accepted. So it can be concluded that there is an influence of the smart wheel learning media on the early literacy abilities of children aged 5 - 6 years at Santo Thomas 1 Medan Kindergarten
Ilmu Sebagai Konstruksi Sosial: Perspektif Filsafat Ilmu Dan Sosiologi Ilmu
Authors: Alam Luktfy , Syukur Muhammad
Published: December 2024

Ilmu pengetahuan telah lama menjadi pilar peradaban manusia, tetapi pandangan mengenai hakikat ilmu telah berkembang dari sekadar fakta objektif menjadi hasil dari konstruksi sosial. Mengkaji ilmu sebagai konstruksi sosial melalui perspektif filsafat ilmu dan sosiologi ilmu. Metode penelitian ini menggunakan literature review atau studi kepustakaan. Penelitian bertujuan untuk menyusun kerangka teori yang komprehensif dan mendalam sebagai dasar pemahaman terhadap ilmu sebagai konstruksi sosial ditinjau dari filsafat ilmu dan sosiologi ilmu. Hasil penelitian ini menunjukkan bahwa pengetahuan tidak hanya dihasilkan melalui metode empiris dan rasional, tetapi juga terikat pada konteks sosial, budaya, dan historis. Filsafat ilmu menyoroti asumsi, metodologi, dan kriteria kebenaran dalam praktik ilmiah, sedangkan sosiologi ilmu mengungkapkan bagaimana interaksi sosial membentuk pengetahuan. Dengan mengintegrasikan teori konstruksi sosial dan filsafat ilmu, artikel ini menawarkan wawasan tentang proses pembentukan pengetahuan serta implikasinya terhadap masyarakat. Refleksi kritis terhadap peran individu dan tanggung jawab sosial dalam ilmu menjadi perhatian utama, menciptakan landasan untuk pengetahuan yang inklusif dan bermanfaat bagi semua.
Pengembangan Media Pembelajaran Berbasis Android pada Mata Pelajaran Informatika
Authors: Ayustyaningtias Rochma , Alinurdin Enjang , Wahyudin Asep , Wahyudin Wahyudin
Published: December 2024

This study aims to develop and evaluate the effectiveness of an Android-based learning media to enhance students' understanding of digital literacy, particularly in distinguishing between facts and opinions. The learning media was developed using the ADDIE model, which includes the stages of analysis, design, development, implementation, and evaluation. In the analysis stage, the software and hardware requirements were identified to support the media development. During the design stage, the media was created using Microsoft PowerPoint and iSpring Suite 11, with the content presented descriptively and in an easily understandable manner. The development stage produced media that was validated by experts, achieving scores of 88% for instructional design, 97% for content quality, and 92% for user experience, indicating excellent quality. The implementation was conducted in grade VIII at SMPN 43 Bandung, with the LORI questionnaire results showing an average score of 84.33%, indicating that the media is highly suitable for use in learning. The evaluation results demonstrated that the Android-based learning media is effective in helping students understand digital literacy and is highly suitable for classroom application.
Systematic Literature Review: Pengaruh Sistem Penerimaan Peserta Didik Baru Berbasis Tes terhadap Adaptabilitas dan Pemenuhan Standar Kompetensi Peserta Didik SMA di Kecamatan Kebayoran Baru
Authors: Risa Kamal Sep Arinda , Nurhattati Nurhattati , Kamaludin Kamaludin
Published: December 2024

This study aims to analyze the impact of a test-based New Student Admission (PPDB) system on student adaptability and the fulfillment of competency standards at the senior high school (SMA) level in Kebayoran Baru District. The study is motivated by the differing effectiveness between the currently dominant zoning system and a test-based academic selection system, particularly in fostering a conducive learning environment and enhancing the quality of education. Employing a quantitative research design, data will be collected through questionnaires and documentation from high school students in the region. Descriptive and inferential statistical analyses will be used to measure the effects of the test-based system on students' learning outcomes, motivation, and engagement. The findings of this study are expected to provide a comprehensive understanding of the test-based selection system's impact on educational quality and offer policy recommendations that balance equity and learning effectiveness.
Peran Komunikasi Interpersonal dan Dialog Kinerja terhadap Kinerja Tim: Systematic Literature Review
Authors: Putriwulan Mentari , Nurhattati Nurhattati , Kamaludin Kamaludin
Published: December 2024

This research analyzes the role of interpersonal communication and performance dialogue on team performance. In an organizational context, effective interpersonal communication plays an important role to enhance cooperation, collaboration, and problem-solving among team members, which in turn affects overall team performance. Weak communication can lead to misunderstandings, hinder collaboration, and reduce team effectiveness. Performance dialog, which involves structured discussions between leaders and team members, also plays an important role in monitoring and improving team performance. Research shows that regularly conducted performance dialogues can clarify goals, improve coordination, and strengthen relationships between team members. This research uses a qualitative method with a literature study approach, reviewing various journals related to interpersonal communication, performance dialog, and team performance. The results show that both, effective interpersonal communication and structured performance dialogue, strongly positively influence team performance. Therefore, organizations need to develop communication skills and support performance dialogue as part of a more effective team management strategy.
Faktor-Faktor yang Mempengaruhi Orang Tua terhadap Minat Memilih Sekolah Dasar Swasta: Systematic Literature Review
Authors: Restarie Maya Diaz , Nurhattati Nurhattati , Kamaludin Kamaludin
Published: December 2024

Choosing the right school early on is very important because it will form the foundation of a child's education and experience that can affect their learning process throughout life. Parents tend to consider various factors before deciding on the right school for their child. This study aims to determine and analyze the factors that influence parents' interest in choosing a private elementary school. The method used in this study is a literature review. The analysis of the discussion shows that parents' interest in choosing a private elementary school is based on various factors, both subjective (such as recommendations and image) and objective (such as facilities and costs). These factors contribute together and influence each other in shaping parents' interest in choosing a particular school. Therefore, private schools need to consider these factors to increase the attractiveness and interest of parents in their institutions.
Systematic Literature Review (SLR): Kepemimpinan Egaliter dalam Pelaksanaan Pendidikan
Authors: Fardila Anisah , Nurhattati Nurhattati , Kamaludin Kamaludin
Published: December 2024

This research wants to see what kind of egalitarian leadership style in educational institutions influences innovative behavior in its employees. The research method used is Systematic Literature Review (Slr). Meanwhile, analyzing journal articles then looks for journals that match inclusion and exclusion. The results of this research explain that the leader's egalitarian leadership style is easy to contact and meet, support from the work social environment is very important for the leader's effectiveness, the leader's effectiveness must go down directly to the bottom, and the leader provides rewards and punishment directly and this can form innovative behavior in employee.
Membangun Pendidikan yang Berkualitas: Antara Idealitas dan Realitas
Authors: Khonsa Nabilah , Rizky Basuki Rahmat , Rusmiyati Lena , Rosyidi Unifah , Takdir Muh.
Published: December 2024

Education plays a crucial role in forming quality human resources. However, several regions in Indonesia actually experience educational gaps. This study was conducted with the aim of determining the factors that cause educational gaps in Indonesia, the role of educational management in influencing the quality of education implementation in various regions, and solutions that can be applied to minimize gaps in the Indonesian education system using the Systemic Literature Review (SLR) method. The results of the study indicate that the factors causing gaps in the quality of education in Indonesia include limited education funds, limited resources and infrastructure, less than optimal teacher quality, and a non-data-based evaluation system. The role of educational management in influencing the quality of education in various regions includes several supporting components, such as Human Resources (HR) management, facilities and infrastructure management, financial management, and educational supervision. The solution to minimize gaps in the Indonesian education system can be done by maximizing education funds, improving the quality of facilities and infrastructure, organizing effective teacher professional development programs, and increasing the participation of all education stakeholders. The results of this study are important in order to reveal the gap between ideals and reality in Indonesian education.
Manajemen Rekrutmen Guru Di Sekolah : Studi Literatur
Authors: Fitriani Rizka Annissa , Rahawarin Benediktus , Kristiyana Yosi , Rosyidi Unifah , Takdir Muh.
Published: December 2024

One of the biggest factors to enhance the quality of education in Indonesia is the educators themselves. The educator or teacher plays a big part in the process of education, which makes the process of recruiting teachers very important. This research aims to find the meaning of recruitment management in school, the process, the strategy, and the challenge of the recruitment process. Using collective works of literatures to study, this research uses the qualitative method approach. Based on the literature, it is concluded that recruitment management in school is a process that starts from planning the process until the placement of the candidates (teachers). There are a lot of strategies and challenges depending on the location of the school. It makes the recruitment management vary based on the location of the school.
Reduction of gossypol in cottonseed meal using halophilic archaeal fermentation for enhanced feed safety and nutritional value
Authors: Kesbiç Fevziye Işıl
Published: December 2024

This study investigated the capacity of halophilic archaea fermentation to detoxify gossypol, a poisonous polyphenolic compound present in cottonseed meal, a major protein source in animal feed. The objective of the study was to investigate the ability of the fermentation process of using halophilic archaeal fermentation to decrease the level of gossypol in cottonseed meal as well as to increase the protein content of the diets. Halophilic microorganisms are able to survive in harsh environmental conditions, offer a potential answer for difficult industrial operations. Cottonseed meal contains high quantities of gossypol, was subjected to fermentation with the halophilic archaeon Halorubrum ezzemoulense in order to reduce gossypol levels and enhance protein content. The study entailed the fermentation of cottonseed meal with H. ezzemoulense, and the amounts of gossypol in the feeds before and after fermentation were assessed using HPLC. Results showed that there was significant (p<0.05) reduction (5.59±0.17 mg/kg) in the gossypol level after microbial fermentation compared to the control which was (139.03±7.17 mg/kg). The protein and lipid content of substrate increased significantly (p<0.05). These analyses revealed modifications in the nutritional values as a result of the fermentation process. The findings indicated a substantial decrease in gossypol levels, coupled with a remarkable rise in protein content. This novel technology not only tackled the drawbacks linked to cottonseed meal but also highlighted the capacity of halophilic archaea fermentation as a sustainable and efficient technique for enhancing the nutritional value of animal feed. Further research could focus on optimizing fermentation, exploring scale-up possibilities, and evaluating broader implications for the livestock industry.
Habitat predilection of loach species Aborichthys uniobarensis through analysis of physicochemical parameters in Poma River, Arunachal Pradesh, Northeast India
Authors: Machahary Krima Queen , Chetia Awarlin , Das Debangshu Narayan
Published: December 2024

The Poma River in Arunachal Pradesh serves as the primary habitat for Aborichthys uniobarensis, an ornamental fish species endemic to biodiversity hotspot. The  present study aimed to investigate the habitat characteristics of Aborichthys uniobarensis within the Poma River. Given the species' predominant presence in this river, understanding the water quality of the Poma River is crucial for further biological research, and of course conservation aspect of this fish species within in-situ as well ex-situ habitat. Over a two-year period (January 2018 to December 2019), the study assessed various physicochemical parameters (pH, water temperature (WT), dissolved oxygen (DO), biochemical oxygen demand (BOD), total dissolved solids (TDS), free carbon dioxide (FCO2), alkalinity, total hardness, electrical conductivity (EC), and salinity) at three sites along the Poma River with seasonal comparisons. Water samples were randomly collected in the morning between 6 a.m. to 10 a.m. Samples were analysed based on the standard methods of APHA (2012). The results indicated consistent conditions across sites but significant variations by season and year (Kruskal-Wallis and Mann-Whitney tests). Minimum values recorded were pH 6.29, WT 18.62°C, DO 6.55 mgL-1, BOD 3.85 mgL-1, TDS 29.78 mgL-1, FCO2 3.89 mgL-1, alkalinity 37.25 mgL-1, total hardness 23.71  mgL-1, EC 57.22 µs/cm, and salinity 0.05 ppt, while maximum values were pH 7.42, WT 25.43°C, DO 7.80 mgL-1, BOD 5.42 mgL-1, TDS 71.12 mgL-1, FCO2  6.48 mgL-1, alkalinity 59.34 mgL-1, total hardness 45.62 mgL-1, EC 117.33 µs/cm, and salinity 0.07 ppt. Simpson correlation tests revealed significant positive and negative correlations among the parameters. PCA analysis highlighted that WT, DO, pH, TDS, BOD, and FCO2 (both physical and chemical factors) have a greater influence on supporting A. uniobarensis, other fish species and the overall health of the river. As the values of habitat parameters were within the acceptable range, the River Poma is congenial for A. uniobarensis along with other species available in this particular riverine habitat.
İzmir ili pamuk tarlalarında görülen zararlı akarlar ile ilişkili bazı predatör türler ve popülasyon gelişimleri
Authors: Kasap İsmail , Ernur Çiftçi Rukiye
Published: December 2024

Bu çalışma İzmir iline bağlı Menemen ve Bergama ilçeleri pamuk alanlarında görülen zararlı akarlar ile ilişkili bazı türleri saptamak ve bu türlerin popülasyon gelişimlerini belirlemek amacı ile 2019-2020 yıllarında yürütülmüştür. Çalışmalar sonucunda pamuk alanlarında zararlı olarak Tetrancyhus urticae Koch (Acari: Tetranychidae)’nin kırmızı formu, faydalı türlerden ise 3 takımdan 4 familyaya bağlı 11 avcı tür saptanmıştır. Bu familyalar içerisinde, zararlı akarlar ile yoğun olarak beslenen ve onların popülasyonları ile ilişkili olan Phytoseiidae (Acari) familyası, 2 cinse ait 3 tür ile en önemli grubu oluşturmuştur. Avcı böceklerden Coccinellidae (Coleoptera) familyasından 4 cinse bağlı 6 tür ve Thripidae ile Acolothripidae (Thysanoptera) familyalarından ise 2 predatör tür belirlenmiştir. Bu türler içerisinde Phytoseiulus persimilis Athias-Henriot en yaygın tür olarak gözlenmiştir. Bu avcı akarların pamuk alanlarında, Temmuz ayının sonu ile Ağustos ayının ortalarında yaprak başına ortalama 20-21 akar ile en yüksek popülasyon yoğunluğuna ulaşabildikleri gözlenmiştir.