bluuebunny/crossref_metadata_2025 huggingface dataset:
The Correlation between Secretory Phospholipase A2 Type IIA Levels and Mean Platelet Volume among Type 2 Diabetes Mellitus Patients
Authors:   Faculty of Medicine, Universitas Pembangunan Nasional ‘Veteran’ Jakarta, Sekararum Woro Ayu , Bustamam Nurfitri ,   Department of Internal Medicine, Prof. Dr. Soerojo Mental Hospital, Magelang, Muktamiroh Hikmah ,   Department of Internal Medicine, Prof. Dr. Soerojo Mental Hospital, Magelang, Mahmudji Harli Amir ,   Department of Internal Medicine, Prof. Dr. Soerojo Mental Hospital, Magelang
Published: February 2021

Background: Platelet activity plays a role in the occurrence of diabetic angiopathy with an increase in mean platelet volume (MPV) as a marker of platelet activity. Platelet activity is influenced by phospholipase A2 type IIA (sPLA2 type IIA), which is a lipid-mediating enzyme that connects the pathogenesis of Diabetes Mellitus (DM) with complications of diabetic angiopathy. This study aimed to examine the relationship between levels of type IIA sPLA2 and MPV among type II DM patients. Subjects and Method: This was a cross-sectional study. A total of 63 patients with type II DM was selected for this study. The inclusion criteria for the study subjects were type 2 diabetes mellitus patients who did not experience an infectious disease, acute inflammation, trauma, surgery or malignancy, anemia, taking antiplatelet drugs, having abnormal platelet counts, and smoking. The dependent variable was levels of type IIA sPLA2. The independent variable was MPV. The data were obtained from the medical records of Prof. Dr. Soerojo Mental Hospital, Magelang. The data were analyzed using Spearman correlation test. Results: The study showed the median level of sPLA2 type IIA was 3841.50 ng / dL and the average MPV value was 7.36 fl. The results of the Spearman correlation analysis showed that there was no relationship between sPLA2 type IIA and MPV (p = 0.551), but there was a tendency for an increase in type IIA sPLA2 followed by an increase in MPV value (r = 0.077). There was a difference in the average MPV value in the subject group with DM ≤ 10 years and> 10 years (p = 0.009), and it was statistically significant. Conclusion: There is a tendency for an increase in type IIA sPLA2 followed by an increase in the MPV value among type II DM patients. Keywords: type II diabetes melitus, type IIA sPLA2 enzyme, mean platelet volume Correspondence: Woro Ayu Sekararum. Faculty of Medicine, Universitas Pembangunan Nasional ‘Veteran’ Jakarta. Jl, Rumah Sakit Fatmawati, Pondok Labu, South Jakarta, Indonesia. E-mail: woroayu.sekararum@gmail.com. Mobile: 0811975511 DOI: https://doi.org/10.26911/the7thicph.01.09
The Influence of Social Capital, Parenting, and Environment on Quality of Life among 2-4 Years Old Children
Authors:   Doctoral Program of Development Counseling, Universitas Sebelas Maret, Wahyuningsih Heni Puji ,   School of Health Polytechnis, Yogyakarta, Indonesia, Murti Bhisma ,   Masters Program in Public Health, Universitas Sebelas Maret, Solo, Indonesia, Lestari Eny ,   Masters Program in Development Counseling, Postgraduate Program, Universitas Sebelas Maret, Solo, Indonesia, Reviono Reviono ,   Faculty of Medicine, Universitas Sebelas Maret, Solo, Indonesia
Published: February 2021

Background: Quality of life is actually a broader construct that encompasses aspects of life that may not be amenable to healthcare service. The quality of life of children is a subjective perception of satisfaction or happiness on quality of life. The quality of life is influenced by various factors, namely health conditions, socio-economic status, parenting styles, and the environment. According to HL Bloom’s theory, health status is determined by 40 percent of environmental factors, 30 percent of behavioral factors, 20 percent of health services, and 10 percent of genetics or heredity. The purpose of this study was to determine the effect of social capital, parenting, and the environment on the quality of life among children. Subjects and Method: This was a retrospective cohort study. Total of 400 children aged 2-4 years old who reside in the desa layak anak villages and ordinary villages in the region of Sleman regency. The dependent variable was quality of life among children. The independent variables were social capital, parenting, and the environment. Data were obtained from in-depth interview and questionnaire. Data were analyzed using path analysis. Results: The good quality of life of children was affected directly by positive social capital (b = 0.084; SE = 0.049; p = 0.001), good parenting style (b = 0.123; SE = 0.050; p <0.001), and good environment (b = 0.128; SE = 0.048; p <0.001). Conclusion: Social capital, parenting and environment have a direct influence on the quality of life among children. Keywords: quality of life, children, social capital, parenting, environment Correspondence: Heni Puji Wahyuningsih. Doctoral Program of Development Counseling, Universitas Sebelas Maret/ School of Health Polytechnis, Yogyakarta, Indonesia. Email: heni.pujiw@-poltekkesjogja.ac.id DOI: https://doi.org/10.26911/the7thicph.01.15
A Compliance on Profilactical as A Dominant Factor towards Filariasis Events in Jambi Province as A High Endemis Regency
Authors:   Study Program of Public Health, Universitas Jambi, Kalsum Ummi , Jumati Jumati ,   Study Program of Public Health, Universitas Jambi, Muhammad Damris ,   Study Program of Public Health, Universitas Jambi
Published: February 2021

Background: Tanjung Jabung Timur Regency is a district where filariasis is endemic. In 2018, the Microfilaria rate (Mf rate) was 1.33% and is the only district / city in Jambi Province with an Mf rate > 1%, so mass treatment was performed again for 2 years (2017-2018), but cases have still been identified. Novelty in 2019. This study aimed to analyze the relationship between the incidence of filariasis in the physical, biological, social and cultural environment and the dominant factors in the incidence of filariasis. Subjects and Method: This was a case control design conducted in Tanjung Jabung Timur Regency from March to July 2020. Total of 84 patients with filariasis were enrolled in this study. The dependent variable was the incidence of filariasis while the independent variables were the socio-cultural environment and individual characteristics (age, education, occupation, income, level of knowledge, spending habits of the day, preventive measures, and compliance with prophylactic medication), attitude (physical environment), The data were collected using questionnaire and environmental observation. Data were analyzed using a multiple logistic regression. Results: Most of patients with filariasis were male (61.9%), had low education (73.8%), was a farmer, and 60% had a job at risk of developing filariasis. Age (OR = 0.16 ; 95%CI= 0.06 to 0.41), education (OR = 4.50 ; 95%CI= 1.56 to 12.96), occupation (OR = 4.66, 95% CI = 1.76 to 12.31), adherence to taking prophylactic medication (OR = 4.70, 95% CI = 1.83 to 12.04) were affected on the filariasis incidence. Adherence to taking prophylactic drugs was the most dominant risk factor for filariasis (OR = 12.97; 95% CI = 3.35 to 50.15). Conclusion: Following control for resting place, occupation, age and height of residence, the most dominant factor in the incidence of filariasis is adherence to taking prophylactic drugs. Keywords: adherence, prophylaxis, filariasis, risk factors, environment Correspondence: Ummi Kalsum. Study Program of Public Health, Universitas Jambi. Jl. Tri Brata, Km 11 Unja Campus Pondok Meja Mestong, Kab. Muaro Jambi. Email: ummi2103@unja.ac.id. Mobile: 081314385775 DOI: https://doi.org/10.26911/the7thicph.01.16
Analysis of Earthquake Preparedness Measures in Students at Elementary School, Denpasar, Bali
Authors:   Institute of Technology and Health, Bali, Yusniawati Yustina Ni Putu , Suantika Putu Inge Ruth ,   Institute of Technology and Health, Bali
Published: February 2021

ABSTRACT Background: In addition to unsuccessful policies to prepare communities for disaster reduction, the high risk of earthquakes and their harmful consequences indicate that more consideration should be given to social factors in this regard. All community shelters are vulnerable to disasters, especially children, so efforts are needed to determine disaster preparedness factors for elementary school students in Denpasar City. This study aimed to analyzed of earthquake preparedness measures in students at elementary school, Denpasar, Bali. Subjects and Methods: This was a descriptive study conducted at an elementary school in Denpasar from January to September. A sample of 350 elementary school students in Denpasar whose schools have a disaster preparedness school (SSB) program selected by purposive sampling. The inclusion criteria were elementary school students grades 5 and 6 in Denpasar City, who can read fluently and are willing to be research respondents. The exclusion criteria were respondents who refused to be research subjects. The data were collected by 40 questions, where knowledge was 10 items, attitude was 10 items, facilities and infrastructure were 10 items, and IEC was 10 items. The data was analyzed by descriptively Results: The preparedness factors of elementary school students in facing earthquake disasters were still low. There were five earthquake preparedness factors for elementary students in Denpasar, namely (1) experience, (2) knowledge, (3) attitude, (4) facilities and (5) infrastructure, and IEC. The dominant knowledge variable of elementary school students is less than 233 (63.7%), the prevalent attitude variable is negative 244 (64%), the prevalent facilities and infrastructure variable are less than 215 (61.4%), and 300 (85.7%) dominant information and education communication. Conclusion: It is essential to be able to improve these preparedness factors with a variety of continuous education and training for elementary students, and health workers should work together with regional disaster management agency to establish disaster prepared schools in Denpasar City. Keywords: preparedness factors, students, and earthquake Correspondence: Yustina Ni Putu Yusniawati. Institute of Technology and Health, Bali. Jl. Tukad Balian no. 180 Renon Denpasar-Bali. Email: yustinaindrayana@gmail.com. Mobile: 087860000191 DOI: https://doi.org/10.26911/the7thicph.01.24
Nitrate in Groundwater and Health Risk Assessment: A Cross-Sectional Study in Three Villages in Tanah Merah District, Kelantan, Malaysia During Paddy Pre-Planting Season
Authors:   Department of Environmental and Occupational Health, Faculty of Medicine  and Health Sciences Universiti Putra Malaysia, Syafiq N Muhammad , MS Shaharuddin ,   Department of Environmental and Occupational Health, Faculty of Medicine  and Health Sciences Universiti Putra Malaysia, Abidin Zaenal ,   School of Health Sciences Bhakti Husada Mulia, Madiun, East Java, Indonesia
Published: February 2021

ABSTRACT Introduction: Contamination of nitrate is one of the most common groundwater problems worldwide. Around 70% of residents in the state of Kelantan still rely on groundwater as their primary source of water supply. Extensive usage of fertilizer in agricultural areas may cause nitrate leaching into the groundwater. This study aimed to determine the level of nitrate in groundwater and health risk assessment at three villages in Tanah Merah District, Kelantan, Malaysia. Subjects and Method: This was a cross-sectional study conducted at Tanah Merah district, Kelantan, in January 2020. A total of 52 residents was selected by purposive sampling. The inclusion criteria for study subjects were long life residents, age ≥18 years old, and groundwater as a primary source of drinking supply. The study variables were (1) Level of nitrate in groundwater measured according to age (year), depth (meter), and distance (meter) of well from the agricultural area; and (2) Health risk assessment measured by hazard quotient (HQ). A set of questionnaires consisted of four sections to gather information related to socio-demographic, water usage, living environment, and health status. Groundwater samples were collected in duplicates and were analysed using a Hanna Instruments portable pH/ORP/ISE meter with an attached nitrate electrode. The data were reported descriptively. Results: Nitrate levels were found to be under the maximum acceptable value of 10 mg/L, as stated by the Drinking Water Quality Standard of Malaysia. Nitrate level ranged from 0.22 to 8.81 mg/L (Mean= 2.94; SD= 2.27). Spearman rho correlation showed that nitrate level was significantly and negatively correlated the age of wells (r= -0.31; p= 0.025). Nitrate level was not significantly correlated with the depth (r= 0.19; p= 0.183) and distance of wells (r= -0.05; p= 0.751). Hazard quotient (HQ) for all study subjects was <1, which means that exposure to nitrate contained drinking water in study subjects was not detrimental to health. Conclusion: Nitrate levels were below the maximum acceptable value, but continuous monitoring from health authorities is essential since other seasons of paddy planting may contribute higher deposition of nitrate into groundwater. Keywords: nitrate, groundwater, levels, hazard quotient, Tanah Merah Correspondence: Muhammad Syafiq N. Department of Environmental and Occupational Health, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia. UPM Serdang, Selangor, Malaysia. Email: syafiqnor29@gmail.com. Mobile: +601140731881. DOI: https://doi.org/10.26911/the7thicph.01.27
Multilevel Analysis of Factors Associated with Performance of Midwives in Integrated Antenatal Care Service in Pati, Central Java
Authors:   School of Health Sciences Bakti Utama, Pati, Central Java, Marfu’ah Siti , Wijayanti Irfana Tri ,   School of Health Sciences Bakti Utama, Pati, Central Java, Rofika Ana ,   School of Health Sciences Bakti Utama, Pati, Central Java
Published: February 2021

ABSTRACT Background: In 2017, nearly 295,000 women died during and after pregnancy and childbirth. In low-resource situations, the vast majority of maternal death (94%) occurred, and most could have been avoided. This study aimed to analyze the factors associated with the performance of midwives in integrated antenatal care service in Pati, Central Java. Subjects and Method: This was a cross-sectional study carried out at 26 integrated health posts (posbindu) in Pati, Central Java. A sample of 130 midwives randomly was selected for this study. The dependent variable was work performance of midwives. The independent variables at level 1 were age, employment status, workload, working time, leadership perception, and healthcare facility. The independent variable at level 2 was posbindu. The data were collected using questionnaire. The data were analyzed by a multilevel linear regression. Results: Work performance of midwives increased with working time (OR= 0.19; 95% CI= 0.04 to 0.33; p= 0.012) and healthcare facility (OR= 0.26; 95% CI= -0.77 to 1.31; p = 0.610). Work performance of midwives decreased with age (b= -0.07; 95% CI= -0.05 to 0.13; p= 0.100), employment status (b= -0.87; 95% CI= -1.89 to 0.15; p= 0.096), workload (b= -0.22; 95% CI= -0.45 to 0.01; p= 0.058), leadership perception (b= -0.002; 95% CI= -0.08 to 0.07; p= 0.949). Posbindu had strong contextual effect on work performance of midwives with ICC= 8.60%. Conclusion: Work performance of midwives increases with working time and decreases with employment status and workload. The work performance associated with age, healthcare facility, and leadership perception, but it is statistically non-significant. Posbindu has strong contextual effect on integrated antenatal care (ANC) performance of midwives. Keywords: performance of midwives, contextual effect, antenatal care Correspondence: Siti Marfu’ah. School of Health Sciences Bakti Utama, Pati, Central Java. Email: marfuah@stikesbup.ac.id. Mobile: +6285729885380. DOI: https://doi.org/10.26911/the7thicph.01.30
Factors Associated with Stroke: Evidence from Indonesian Family Life Surveys 2015
Authors:   Masters Program in Public Health, Universitas Sebelas Maret, Delimasari Trisakti Halimah , Widyaningsih Vitri ,   Faculty of Medicine, Universitas Sebelas Maret
Published: February 2021

ABSTRACT Background: Stroke is a major public health problem, affecting millions of people in both developed and developing countries. In Indonesia stroke prevalence in 2013 rose from 7% to 10.9%.The purpose of this study was to determine factors associated with stroke using the Indonesian family live survey 5 (IFLS-5) year 2015. Subjects and Method: This was a cross sectional study. A sample of 34,250 study subject aged ≥18 years old was selected for this study. The dependent variable was stroke. The independent variables were age, gender, body mass index (BMI), hypertension, cholesterol level, and diabetes mellitus. The data were analyzed by a multiple logistic regression. Results: The risk of stroke increased with age ≥40 years old (OR= 5.09; 95%CI= 3.13 to 8.26; p= 0.001), male (OR= 1.86; 95%CI= 1.36 to 2.52; p= 0.001), hypertension (OR= 8.71; 95%CI= 6.09 to 12,46; p= 0.001), diabetes mellitus (OR= 1.89; 95%CI= 1.22 to 2.95; p= 0.004), and cholesterol level (OR= 3.42; 95%CI= 2.35 to 4.99; p= 0.001). The risk of stroke decreased with normal BMI (OR= 0.75; 95%CI= 0.58 to 0.96; p= 0.026). Conclusion: The risk of stroke increases with age ≥40 years old, male, hypertension, cholesterol level, and diabetes mellitus. The risk of stroke decreases with normal BMI. Keywords: stroke, Indonesian family life survey 5 Correspondence: Trisakti Halimah Delimasari. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java, Indonesia. Email: trisaktihd1994@-gmail.com. Mobile:+6285293994629. DOI: https://doi.org/10.26911/the7thicph.01.34
Meta Analysis on Obesity and Diabetes Melitus as Risk Factor Hypertension in Police and Military Personnel
Authors:   Masters Program in Public Health, Universitas Sebelas Maret, Pardosi Firman , Rahardjo Setyo Sri ,   Faculty of Medicine, Universitas Sebelas Maret, Dewi Yulia Lanti Retno ,   Faculty of Medicine, Universitas Sebelas Maret
Published: February 2021

ABSTRACT Background: The strenuous duties of emergency responders (police officers andmilitary personnel) may interact with their personal risk profiles, including elevated blood pressure, obesity, and diabetes mellitus to precipitate acute cardiovascular events. The purpose of this study was to investigate the associations between obesity, diabetes melitus, and hypertension in police and military personnel using meta-analysis. Subjects and Method: This was a meta-analysis and systematic review. The articles which published from year 2000 to 2020 were obtained from Google Scholar, Springer Link, ProQuest, and Science Direct databases, which published from 2000 to 2020. Cross sectional or case control full-text articles were selected for this study. There were 1,822 polices and military personnel conducted as data sample. The articles were reviewed by PRISMA diagram and analyzed by RevMan 5.3. Results: The risk of hypertesion in police and military personnel increased with obesity (OR= 2.51; 95% CI= 1.47 to 4.29; p= 0.007), and diabetes (OR= 2.12; 95% CI= 1.35 to 3.32; p= 0.001). Conclusion: The risk of hypertesion in police and military personnel increases with obesity and diabetes. Keywords: hypertension, obesity, diabetes melitus Correspondence: Firman Pardosi. Masters Program in Public Health, Universitas Sebelas Maret, Jl. Ir. Sutami 36A, Surakarta 57126, Central Java, Indonesia. Email: pardosi.fp@gmail.com. Mobile: +6285261423865. DOI: https://doi.org/10.26911/the7thicph.01.36
Social Capital Phenomenology Study among People Who Treat A Mental Disorder Caregivers
Authors:   Doctoral Program of Community Development / Empowerment, Universitas Sebelas Maret, Herdaetha Adriesti , Sudiyanto Aris ,   Universitas Sebelas Maret, Sumanto RB ,   Universitas Sebelas Maret, Suleman Endang Sutisna ,   Universitas Sebelas Maret, Kusuma Wijaya ,   Faculty of Medicine, Universitas Sebelas Maret
Published: February 2021

ABSTRACT Background: It’s a stressor to have a family of mental illnesses. Financial, social, psychological, and physical burdens are created by looking after people with mental disorders. For the patient, the family is the informal caregiver. It is important to discuss, with a great burden, how social capital can be developed and how the role of social capital is played in treating people with mental disorders. The research was carried out on Javanese individuals who have a cultural structure that prioritizes the importance of peace in collective life. Not only the nuclear family, but also the extended family and the larger community are active in the life of Javanese society. This study aimed to describe the social capital phenomenology study among people who treat mental disorder caregivers. Subjects and Method: This was a qualitative study using a phenomenological study approach. The study was carried out in Surakarta City, Central Java, in September and October 2019. These study subjects were people who were carers for people with mental disorders. The sample was taken using purposive sampling technique. Data were collected using in-depth interviews and observation. Qualitative data analysis was obtained by means of data reduction, data presentation, and drawing conclusions and verification. Data reliability was carried out using NVivo 12 software. Data validity was done by matching the results of interviews with observations, as well as multiple interviews. Results: Data was collected from four respondents with different demographic backgrounds. Six themes were obtained, namely 1) trust in God, government, family, and neighbors; 2) The role of family and neighbors in seeking help; 3) The role of family and neighbors in caring for patients; 4) building social networks; 5) Participation in society; and 6) Social capital is dynamic. Conclusion: The respondents are found to have the same social cognitive capital, but different social structural capital. The level of education, the economic level, self-esteem, and the behavior of people with mental disorders are influenced by structural social capital. Family and neighbors can have a positive or negative role in looking after people with mental disorders. They also play a role in the decision to seek assistance for individuals with mental disorders. Keywords: mental disorders, carers, social capital Correspondence: Adriesti Herdaetha. Doctoral Program of Community Development / Empowerment, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta, Central Java. Email: aherdaetha@gmail.com. Mobile: +628122582995 DOI: https://doi.org/10.26911/the7thicph.01.40
Factors Related to Genital Hygiene Behavior Among Female Underwent Treatment at Dr. Moewardi Hospital Surakarta, Indonesia: A Case-Control Study
Authors:   Department of Public Health, Faculty of Medicine, University of Szeged, Szeged, Hungary, Umami Afriza ,   Medical Record and Health Information, Stikes Muhammadiyah Bojonegoro, Bojonegoro, Indonesia,   University of Muhammadiyah Surabaya, Surabaya, Indonesia, Murti Bhisma ,   Master program in public health, Sebelas Maret University, Surakarta, Indonesia, Pratama Tegar Wahyu Yudha ,   Medical Record and Health Information, Stikes Muhammadiyah Bojonegoro, Bojonegoro, Indonesia,   Hospital Administration, Stikes Muhammadiyah Bojonegoro, Bojonegoro, Indonesia, Fithri Istiqlal ,   Hospital Administration, Stikes Muhammadiyah Bojonegoro, Bojonegoro, Indonesia, Nasrullah Dede ,   University of Muhammadiyah Surabaya, Surabaya, Indonesia
Published: February 2021

ABSTRACT Background: Maintaining genital cleanliness is very important for women because intimate organ problems can cause female tract infections. This study aimed to find out the factors associated with genital hygiene behavior in women. Methods: A case-control study was carried out in female underwent treatment at Dr. Moewardi Hospital Surakarta, Indonesia, from December 2017 to February 2018. A structured questionnaire was used to collect data from 178 participants, who consisted of 56 cases and 122 controls. The dependent variable was genital hygiene behavior. The independent variables were stress, exposure to social media regarding genital hygiene, environmental sanitation, husband’s education, and support. Logistic regression was employed for data analysis. Results: Genital hygiene behavior increased with exposure to social media related to genital hygiene (OR= 9.20; 95% CI= 3.87 to 21.87, p<0.001), good environmental sanitation (OR= 5.16; 95% CI= 2.19 to 12.14, p<0.001), high husband’s education (OR= 6.49; 95% CI= 2.23 to 18.91, p=0.001) and support (OR= 2.88; 95% CI= 1.24 to 6.67, p=0.013). While women who experienced psychological problems such as stress decreased genital hygiene behavior (OR= 0.25; 95% CI= 0.94 to 0.71, p=0.009). Conclusions: Genital hygiene behavior in women increases with exposure to social media related to genital hygiene, adequate environmental sanitation, high husbands’ income, and support. In contrast, stress decreases women’s behavior in practicing genital hygiene. Keywords: Genital hygiene behavior, social media, environmental sanitation, stress, husband’s education, and support. Corresponding author: Afriza Umami, MPH. Department of Public Health, Faculty of Medicine, University of Szeged, Szeged, Dóm tér 10 H-6720, Hungary. E-mail: umami.afriza@med.u-szeged.hu DOI: https://doi.org/10.26911/the7thicph.05.27
Effectiveness of Consuming Decoction of Bay Leaves (Syzygium Polyanthum) and Soursop Leaves (Annona Uricata) on Reducing Uric Acid Levels in Elderly in Grobogan, Central Java
Authors:   Master Program in Public Health, Universitas Negeri Semarang, Rukmana Dewi ,   School of Health Sciences An Nur Purwodadi, Riniasih Wahyu ,   School of Health Sciences An Nur Purwodadi
Published: February 2021

ABSTRACT Background: Gout remains a common health problem of elderly. Uric acid occurs due to excessive consumption of purines. Alternative therapy using herbal which contains uric acid reducing agents can be considered the treatment for gout. Syzgium Polyantum and Annona Muricata L leaves are found the component of flavonoids, tannins, and essential oils with citrate oil and eugenol which can reduce uric acid levels. This study aimed to examine the effectiveness of consuming decoction of bay leaves (Syzygium polyanthum) and soursop leaves (Annona uricata) on reducing uric acid levels in elderly in Grobogan, Central Java. Subjects and Method: A quasi-experimental with pretest and posttest control group design conducted at Purwodadi, Central Java. A sample of 20 elderlies was selected for this study and allocated into two groups: (1) Experimental group that received decoction Bay leaves (Syzgium polyanthum) and Soursop leaves (Annona Muricate L), and (2) Control group that received no intervention. The dependent variable was uric acid level in elderly. Uric acid level was measured by digital blood uric acid test. The independent variables were consuming decoction Bay leaves (Syzgium polyanthum) and Soursop leaves (Annona Muricate L). The data were analyzed by Mann-Whitney test. Results: Bay and Soursop leaves had effect to reduce the uric acid level in elderly. After the intervention, mean of the Bay leaves (Mean= 7.40; SD= 13.60) was lower than the Soursop leaves (Mean= 13.60; SD= 0.57), and it was statistically significant (p= 0.018). Conclusion: Bay and Soursop leaves have the effect to reduce the uric acid level in elderly. There is significant mean difference in effectiveness of Bay and Soursop leaves. Keywords: uric acid, Annona Muricate L, Syzgium polyanthum, elderly Correspondence: Dewi Rukmana. Master Program, Universitas Negeri Semarang. Gedung B 202 Pascasarjana UNNES, Kelud Utara III Petopon Gajah Mungkur, Semarang, 50273. Email: dewirukmana737@students.unnes.ac.id. Mobile: +6285726418732. DOI: https://doi.org/10.26911/the7thicph.05.30
Meta Analysis: The Effect of High-Intensity Interval Training on Low Density Lipoprotein Level in Patients with Type 2 Diabetes Melitus
Authors:   Masters Program in Public Health, Universitas Sebelas Maret, Adelita Sela Putri , Pamungkasari Eti Poncorini ,   Departement of Public Health, Faculty of Medicine, Universitas Sebelas Maret, Murti Bhisma ,   Masters Program in Public Health, Universitas Sebelas Maret
Published: February 2021

ABSTRACT Background: High intensity interval training (HIIT) is a protocol of short work intervals of vigorous to high intensity interspersed with active or passive (cessation of movement) recovery periods. HIIT has been employed since the mid-20th century to improve athletic exercise performance. Regular exercise reduces elevated low-density lipoprotein (LDL), atherosclerosis formation, and risk factors of cardiovascular disease (CVD). This study aimed to examine the effect of high-intensity interval training on low density lipoprotein level in patients with type 2 diabetes mellitus (DM). Subjects and Method: This was meta-analysis and systematic review. The study was conducted by search published article from year 2010 to 2020 in PubMed, Science Direct, Research Gate, and Google Scholar databases. The inclusion criteria were full text, using randomized controlled trial study design, high-intensity interval training intervention, and reporting mean and standard deviation. Study subjects were type 2 DM patients aged 25-65 years. The study outcome was LDL reduction. The articles were analyzed by PRISMA flow chart and Revman 5.3. Results: 7 studies from America, Europe, Australia, and Asia showed that high intensity interval training reduced LDL level in type 2 DM patients (Mean Difference= -0.06; 95% CI= 1.32 to -0.47; p<0.001) with I2= 92% (p <0.93). Conclusion: High-intensity interval training reduces LDL level in type 2 DM patients. Keywords: high-intensity interval training, low density lipoprotein Correspondence: Sela Putri Adelita. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: Selaadelita558@gmail.com. Mobile: 085357117517. DOI: https://doi.org/10.26911/the7thicph.05.42
A Meta-Analysis of Knee Orthosis Uptake in Reducing Pain in Patients with Knee Osteoarthritis
Authors:   Masters Program in Public Health, Universitas Sebelas Maret, Anggriani Atika Febri , Kristiyanto Agus ,   Faculty of Teaching and Educational Sciences, Universitas Sebelas Maret, Rahardjo Setyo Sri ,   Faculty of Medicine, Universitas Sebelas Maret
Published: February 2021

ABSTRACT Background: Osteoarthritis (OA) of knee joint is a degenerative disease that results in decreased function and pain. Orthotic devices can reduce knee adduction moment, pain, and improve function in knee OA. The purpose of this study was to examine knee orthosis uptake in reducing pain in patients with knee osteoarthritis. Subjects and Method: A meta-analysis and systematic review was conducted by search published articles from PubMed, Science Direct, Google Sscholar, Mendeley, and Clinical key databases. Keywords used “knee orthosis” OR “KO” AND “valgus knee brace” AND “brace” AND “knee support” AND “valgus knee support” AND “osteoarthritis” AND “patellofemoral osteoarthritis” AND “knee pain” AND “effect knee orthosis for osteoarthritis” AND “randomized controlled trial”. The inclusion criteria were full text and using randomized controlled trial study design. The articles were selected by PRISMA flow chart and the quantitative data were analyzed by Revman 5.3. Results: 6 studies reported that knee orthosis uptake reduces pain in patients with knee osteoarthritis (Mean Difference= -0.53; 95% CI= -1.39 to 0.33; p= 0.230) with heterogeneity I2= 95%. Conclusion: Knee orthosis uptake reduces pain in patients with knee osteoarthritis. Keywords: osteoarthritis, pain, knee orthosis, knee valgus brace Correspondence: Atika Febri Anggriani. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: atikaanggriani07@gmail.com. Mobile: 085728794960. DOI: https://doi.org/10.26911/the7thicph.05.44
Lateral Wedge Insole Uptake in Reducing Pain in Patients with Knee Osteoarthritis: A Meta-Analysis Study
Authors:   Masters Program in Public Health, Universitas Sebelas Maret, Fatati Muhibbah , Rahardjo Setyo Sri ,   Faculty of Medicine, Universitas Sebelas Maret, Prasetya Hanung ,   Health Polytechnics, Ministry of Health, Surakarta
Published: February 2021

ABSTRACT Background: The increase in rates of knee replacement for osteoarthritis has made the identification of effective nonsurgical treatments a high priority. One type of treatment for medial knee osteoarthritis involves reducing medial loading to ease the physical stress applied to that compartment of the joint. The wedge is placed under the sole of the foot and angulated so that it is thicker over the lateral than the medial edge, transferring loading during weight bearing from the medial to the lateral knee compartment. This study aimed to investigate the effect of lateral wedge insole uptake in reducing pain in patients with knee osteoarthritis. Subjects and Method: A meta-analysis and systematic review conducted by search published articles from PubMed, Science Direct, Google Scholar, Mendeley, and Clinical key databases. Keywords used “Lateral Wedge Insole” OR “Insole” AND “Foot Orthosis “AND “osteoarthritis” AND “patellofemoral osteoarthritis” AND “knee pain” AND “medial knee osteoarthritis “AND” effect lateral wedge insole for osteoarthritis” AND “randomized controlled trial”. The inclusion criteria were full text, using randomized controlled trial (RCT) study design, and reporting effect size (mean and standard deviation). The intervention was lateral wedge insole with comparison non lateral wedge insole. The study outcome was pain. The data were analyzed by Revman 5.3. Results: 6 studies were met the inclusion criteria. This study showed that the use of lateral wedge insole reduced pain in patients with knee osteoarthritis (Mean Difference= -0.17; 95% CI= -0.51 to 0.18; p= 0.340) with heterogeneity I2= 77%. Conclusion: Lateral wedge insole use reduced pain in patients with knee osteoarthritis. Keywords: knee osteoarthritis, lateral wedge insole, randomized control trial Correspondence: Muhibbah Fatati, Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: muhibbahfatati@gmail.com. Mobile: 089633466598. DOI: https://doi.org/10.26911/the7thicph.05.45
Meta Analysis: The Effect of Type 2 Diabetes Mellitus in Stroke
Authors:   Masters Program in Public Health, Universitas Sebelas Maret, Suprayogi Dody , Kristiyanto Agus ,   Faculty of Teaching and Educational Sciences, Universitas Sebelas Maret, Prasetya Hanung ,   Study Program in Acupuncture, Health Polytechnics, Ministry of Health, Surakarta
Published: February 2021

ABSTRACT Background: Diabetes can cause pathologic changes in blood vessels at various locations and can lead to stroke if cerebral vessels are directly affected. Additionally, mortality is higher and poststroke outcomes are poorer in patients with stroke with uncontrolled glucose levels. The purpose of this study was to examine the effect of type 2 diabetes mellitus in stroke. Subjects and Method: Meta analysis and systematic review was conducted by collecting published articles from PubMed, Science Direct, Google Sscholar, Mendeley, and Clinical key databases. Keywords used “Diabetes Mellitus” AND “Type 2 Diabetes Mellitus” AND “Stroke” AND “Risk Factor of Stroke” AND “Cross-sectional”. The inclusion criteria were full text and using cross-sectional study design. The articles were collected and selected by PRISMA flow chart. The quantitative data were analyzed by Review Manager 5.3. Results: Meta analysis from 6 studies reported that type 2 DM increased the risk of stroke (aOR= 1.90; 95% CI= 1.41 to 2.57; p<0.001) with heterogeneity (I2= 78%). Conclusion: Type 2 DM increases the risk of stroke. Keywords: type 2 diabetes mellitus, stroke Correspondence: Dody Suprayogi. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: 23dhodik.yogi@gmail.com. Mobile: 08562772052. DOI: https://doi.org/10.26911/the7thicph.05.46
The Effects of Ferric Carboxymaltose Versus Iron Sucrose on the Ferritin Level in Pregnant Women with Anemia: A Meta-Analysis
Authors:   Masters Program in Public Health, Universitas Sebelas Maret, Nirwana Astika Candra , Dewi Yulia Lanti Retno ,   Faculty of Medicine, Universitas Sebelas Maret, Murti Bhisma ,   Masters Program in Public Health, Universitas Sebelas Maret
Published: February 2021

ABSTRACT Background: Prophylactic oral iron is recommended during pregnancy to meet the increased requirement during the antenatal period. The most commonly used iron preparation for anemia in pregnancy is iron sucrose complex (ISC). The purpose of this study was to compare the effects of ferric carboxymaltose versus iron sucrose on the ferritin level in pregnant women with anemia. Subjects and Method: This was a meta-analysis study. The study was conducted by collecting published articles from 2010 to 2019 in PubMed, Science Direct, and Google Scholar databases. The keywords used to search the articles including “Ferric Carboxymaltose”, “Ferric Carboxymaltose and anemia in pregnancy”, and “the effect of Ferric Carboxymaltose for anemia”. The inclusion criteria was full text with randomized control trial study, anemia therapy provision using ferric carboxymaltose versus iron sucrose, and the study subjects were pregnant women with anemia. The selected articles were analyzed using Revman 5.3. Results: 5 articles that meet the inclusion criteria were selected for this study. There was high heterogeneity between experiment group (I2 = 96%; p= 0.020). Therefore, this study used random effect model. Ferric carboxymaltose provision increased feritin level 0.89 times than iron sucrose (Mean Difference= 0.89; 95% CI= 0.12 to 1.66; p<0.001). Conclusion: Ferric carboxymaltose is effective to increased feritin level in pregnant women. Keywords: ferric carboxymaltose, iron sucrose, randomized controlled trial Correspondence: Astika Candra Nirwana. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir Sutami 36A, Surakarta 57126, Central Java. Email: astikacandranirwana2796@gmail.com. Mobile: 085640018896 DOI: https://doi.org/10.26911/the7thicph.05.48
The Effectiveness of Acupuncture in Reducing Musculoskeletal Pain: A Meta-Analysis
Authors:   Masters Program in Public Health, Universitas Sebelas Maret, Putri Kurnia Eka , Murti Bhisma ,   Masters Program in Public Health, Universitas Sebelas Maret, Prasetya Hanung ,   School of Health Polytechnics, Ministry of Health Surakarta
Published: February 2021

ABSTRACT Background: Musculoskeletal disorder affects the musculoskeletal system’s function, which includes tendons, bursae, bones, muscles, joints, and ligaments. Acupuncture is one of the non-pharmacological alternative therapies for treating musculoskeletal disorders. This study aimed to examine the effectiveness of acupuncture in reducing pain in musculoskeletal diseases. Subjects and Method: This was a meta-analysis and systematic review. The study was collected articles from PubMed, ProQuest, Science Direct, Scopus, Spinger Link, and Google Scholar databases. The inclusion criteria were full text in English language and used randomized controlled trial study design. There were 8 articles with 466 study subjects comprised in two groups, including 236 people received acupuncture therapy (intervention) and 230 people received sham acupuncture (control). The selected articles were analyzed by ReVman 5.4. Results: This study had high heterogeneity (I2= 90%; p<0.001). This study reported that acupuncture was more effective to reduce musculoskeletal pain than sham acupuncture (Mean Difference= 1.63; 95% CI= 0.89 to 2.38; p= 0.001). Conclusion: Acupuncture is more effective to reduce musculoskeletal pain than sham acupuncture. Keywords: acupuncture, musculoskeletal pain Correspondence: Kurnia Eka Putri. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: nia.putrinia@gmail.com. Mobile: +628995212646. DOI: https://doi.org/10.26911/the7thicph.05.52
Meta-Analysis: Acupuncture Therapy in Reducing Blood Pressure on Hypertensive Patients
Authors:   Masters Program in Public Health, Universitas Sebelas Maret, Susilo Fahmi Eko , Prasetya Hanung ,   Study Program in Acupuncture, Health Polytechnics, Ministry of Health, Surakarta, Kristiyanto Agus ,   Study Program in Sports Education and Health Sciences, Universitas Sebelas Maret
Published: February 2021

Background: Blood pressure control is an important component of cardiovascular disease prevention. Despite the advances in the treatment of hypertension; effective management remains poor. Studies have shown that acupuncture facilitated a significant reduction in blood pressure. The purpose of this study was to examine the effectiveness of acupuncture therapy in reducing blood pressure on hypertensive patients. Subjects and Method: This was a meta-analysis and systematic review. The study was conducted by collected articles from PubMed, Google Schoolar, Mendeley, and Hindawi databases. Keywords used “acupuncture hypertension” OR “acupuncture high blood pressure” AND “efficacy acupuncture” AND “hypertension” AND “effect acupuncture for hypertension” AND “randomized controlled trial” AND “visual analogue scale”. The study population was patients with hypertension. The intervention was acupuncture. The comparison was sham acupuncture. The outcome was blood pressure reduction. The inclusion criteria were full text with English language and using randomized controlled trial study design. The selected articles were analyzed by PRISMA flow diagram and RevMan 5.3. Results: 7 articles were studied. There was high heterogeneity between experiment groups (I2= 66%; p= 0.007). Acupuncture therapy was more effective to reduce blood pressure than sham acupuncture (Standardized Mean Difference= 0.13; 95% CI= -0.13 to 0.39; p= 0.320). Conclusion: Acupuncture therapy is effective to reduce blood pressure in patients with hypertension. Keywords: hypertension, acupuncture Correspondence: Fahmi Eko Susilo. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: fahmiekss@gmail.com. Mobile: 081393644991. DOI: https://doi.org/10.26911/the7thicph.05.53
Effect of Obesity and Family History on the Risk of Breast Cancer: Meta Analysis
Authors:   Masters Progamin Public Health, Universitas Sebelas Maret, Ketaren Enge Surabina , Murti Bhisma ,   Faculty of Medicine, Universitas Sebelas Maret, widyaningsih Vitri ,   Faculty of Medicine, Universitas Sebelas Maret
Published: February 2021

Background: Breast cancer is the most common cancer among women worldwide and currently ranked as the fifth leading cause of death from cancer in general. Studies have indicated that breast cancer was strongly associated with a positive family history of breast cancer.The risk of breast cancer also increased with the increasing levels of body‐mass index. This study aimed to examine the effect of obesity and family history on the risk of breast cancer. Subjects and Method: Meta analysis and systematic review was conducted by collecting published articles from Google Scholar, PubMed, Springer Link, DOAJ, and Science Direct databases.Keywords used “breast cancer” AND “risk factors” AND “BMI” OR “body mass index” AND “obesity”AND “family history” AND “cohort” AND “Asia”. The inclusion criteria were full text, using English language, using cohort study design, and reporting adjusted hazard ratio.The study population was Asian women. Intervention was obesity and family history with comparison non-obesity and no family history. The study outcome was breast cancer. The collected articles were selected by PRISMA flow chart. The quantitative data were analyzed by random effect model using Revman 5.3. Results: 6 studies fromTaiwan, Israel, Japan, Malaysia, Thailand, and Korea were selected for this study. This study showed that obesity (aHR= 1.01; 95% CI= 0.67 to 1.52; p= 0.96), with I²= 90% and family history (aHR= 1.69; 95% CI= 1.09 to 2.62; p= 0.02), with I²= 57%, were associated with breast cancer. Conclusion: Obesity and family history are associated with breast cancer. Keywords: breast cancer, obesity, family history Correspondence: Enge Surabina Ketaren. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: ketarenenge3@gmail.com. Mobile: 087838583646. DOI: https://doi.org/10.26911/the7thicph.05.56
Effect of Drumstick (Moringa Oleifera Lam) Leaves Ethanol Extract on Anopheles Aconitus L. Third Instar Larvae Mortality
Authors:   Faculty of Medicine, Universitas Sebelas Maret, Maung Yuzana ,   Masters Program in Public Health, Universitas Sebelas Maret, Handayani Sutartinah Sri ,   Faculty of Medicine, Universitas Sebelas Maret, Aryoseto Lukman ,   Faculty of Medicine, Universitas Sebelas Maret
Published: February 2021

Background: Synthetic insecticides may have the negative effect to nature. Many studies suggested the applications of botanical larvicides as an alternative replacement for synthetic insecticides. This study aimed to examine the effect of Moringa oleifera Lam leaves ethanol extract on the Anopheles aconitus L. third instar larvae mortality. Subjects and Method: This was a laboratory experimental with post-test only con-trol group design conducted at Salatiga, Central Java, in November 2016. A total of 150 Anopheles aconitus L. third instar larvae was selected by convenience sampling method and divided into 6 groups in which contained replication of 25 larvae. One negative control group was added 100 ml distilled water. The other treatment groups were 1 mg/ 100 ml, 10 mg/ 100 ml, 20 mg/ 100 ml, 30 mg/ 100 ml, and 40 mg/ 100 ml of Moringa oleifera Lam leaves ethanol extract. Each test group was repeated four times. The dependent variable was mortality of the larvae. The independent variable was different concentrations of Moringa oleifera Lam leaves ethanol extract. The observation of larvae mortality was conducted after 48 hours of exposure with extract. The data were analyzed by Kruskal-Wallis. Results: Mean of the mortality of Anopheles aconitus L. third instar larvae was dif-ferent in each group, and it was statistically significant (p= 0.008). Conclusion: Moringa oleifera Lam leaves ethanol extract has effect on mortality of Anopheles aconitus L. third instar larvae. Keywords: Moringa oleifera Lam, Anopheles aconitus L., ethanol extract, mortality Correspondence: Yuzana Maung. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta, 57126, Central Java, Indonesia. Email: yuzmg5699@student.-uns.ac.id. Mobile: +6281295346614. DOI: https://doi.org/10.26911/the7thicph.05.59