bluuebunny/crossref_metadata_2025 huggingface dataset:
Modelling the Effects of Roselle Extract, Potato Peel Flour, and Beef Fat on the Sensory Properties and Heterocyclic Amines Formation of Beef Patties Studied by Using Response Surface Methodology
Authors: Pérez-Báez Anna Judith , Valenzuela-Melendres Martin , Camou Juan Pedro , González-Aguilar Gustavo , Tortoledo-Ortiz Orlando , González-Ríos Humberto , Viuda-Martos Manuel
Published: May 2021

Heterocyclic amines (HCAs) are compounds with carcinogenic potential formed during high-temperature processing of meat and meat products. Vegetables or their extracts with high antioxidant capacity can be incorporated into the meat matrix to reduce their formation, but it is necessary to find the optimal levels to achieve maximum inhibition without affecting the sensory properties. The objective of this study was to evaluate the effects of roselle extract (RE, 0–1%), potato peel flour (PP, 0–2%), and beef fat (BF, 0–15%) on the sensory properties and formation of HCAs in beef patties using response surface methodology. IQx, IQ, MeIQx, MeIQ, 4,8-DiMeIQx, and PhIP were identified and quantified by HPLC. Regression models were developed to predict sensory properties and HCAs’ formation. All models were significant (p < 0.05) and showed a R2 > 0.70. Roselle extract and beef fat had a negative linear effect on the formation of the total HCAs, while PP had a positive linear effect. The optimal formula that minimizes the formation of HCAs included 0.63% RE, 0.99% PP, and 11.96% BF. RE and PP are foods that can be used as ingredients in low-fat beef patties to minimize the formation of HCAs without affecting their sensory properties.
Valorisation of Prunus avium L. By-Products: Phenolic Composition and Effect on Caco-2 Cells Viability
Authors: Nunes Ana R. , Gonçalves Ana C. , Alves Gilberto , Falcão Amílcar , Garcia-Viguera Cristina , A. Moreno Diego , Silva Luís R.
Published: May 2021

Prunus avium L. by-products, such as stems, leaves, and flowers, are used in folk medicine to prevent and treat some diseases. However, their phenolic composition and in vitro bioactivities against tumor cells are poorly known. In this work, we compared the phenolic profile and the biological potential of aqueous infusions and hydroethanolic extracts of P. avium leaves, stems, and flowers from Saco cultivar, collected from the Fundão region (Portugal). Among the fifty-two phenolic compounds tentatively identified by HPLC-DAD-ESI/MSn, the hydroxycinnamic acids were the most abundant. Both extracts of stems revealed a higher activity against DPPH•. Meanwhile, hydroethanolic extracts from stems and flowers and aqueous infusions of flowers were the most effective in inhibiting the growth of the human epithelial colorectal adenocarcinoma (Caco-2) cells at concentrations above 200 μg/mL. More detailed knowledge about the phenolic composition and health-promoting properties of Portuguese P. avium by-products allows for increasing the biological and commercial value of these bio-wastes, which may have a positive impact on food and pharmaceutical industries, as on the valorization of the local economy.
Application of PET/Sepiolite Nanocomposite Trays to Improve Food Quality
Authors: Fernández-Menéndez Teresa , García-López David , Argüelles Antonio , Fernández Ana , Viña Jaime
Published: May 2021

New PET and nanosepiolite materials are produced for its application in innovative packaging with better performance. In our previous work, we demonstrate that the use of different percentages of sepiolite modified with different organosilanes improved mechanical and barrier properties of PET. Nanocomposites permeability can decrease up to 30% compared to that of pure PET and the mechanical analyses show that, although PET nanocomposites are more brittle than virgin PET, they are also harder. In the present work, we are going to study the properties of this innovative packaging with real food analyzing mechanical properties related to the product transport together with permeability and microbiological characteristics. At the same time, it has been seen that it is possible to lighten trays, which is very important both industrially and environmentally. On the other hand, a good quality packaging for food needs to ensure that organoleptic and physico-chemical characteristics of the product inside are not modified due to migration of any of the packaging material to the food itself. Results obtained in this work also show lower count of aerobic mesophilic bacteria and Enterobacteriaceae (EB), reducing the incidence of food contaminations by microorganisms.
Metagenetic Analysis for Microbial Characterization of Focaccia Doughs Obtained by Using Two Different Starters: Traditional Baker’s Yeast and a Selected Leuconostoc citreum Strain
Authors: Ferrara Massimo , Sisto Angelo , Mulè Giuseppina , Lavermicocca Paola , De Bellis Palmira
Published: May 2021

Lactic acid bacteria (LAB) decisively influence the technological, nutritional, organoleptic and preservation properties of bakery products. Therefore, their use has long been considered an excellent strategy to improve the characteristics of those goods. The aim of this study was the evaluation of microbial diversity in different doughs used for the production of a typical Apulian flatbread, named focaccia. Leavening of the analyzed doughs was obtained with baker’s yeast or by applying an innovative “yeast-free” protocol based on a liquid sourdough obtained by using Leuconostoc citreum strain C2.27 as a starter. The microbial populations of the doughs were studied by both a culture-dependent approach and metagenetic analyses. The flours used for dough preparation were also subjected to the same analyses. The metagenetic analyses were performed by sequencing the V5–V6 hypervariable regions of the 16S rRNA gene and the V9 hypervariable region of the 18S rRNA gene. The results indicate that these hypervariable regions were suitable for studying the microbiota of doughs, highlighting a significant difference between the microbial community of focaccia dough with baker’s yeast and that of the dough inoculated with the bacterial starter. In particular, the dough made with baker’s yeast contained a microbiota with a high abundance of Proteobacteria (82% of the bacterial population), known to be negatively correlated with the biochemical properties of the doughs, while the Proteobacteria in dough produced with the L. citreum starter were about 43.5% lower than those in flour and dough prepared using baker’s yeast. Moreover, the results show that the L. citreum C2.27 starter was able to dominate the microbial environment and also reveal the absence of the genus Saccharomyces in the dough used for the production of the “yeast-free” focaccia. This result is particularly important because it highlights the suitability of the starter strain for obtaining an innovative “yeast-free” product.
Erratum: Nováková et al. An Analysis of Food Waste in Czech Households—A Contribution to the International Reporting Effort. Foods 2021, 10, 875
Authors: Nováková Petra , Hák Tomáš , Janoušková Svatava
Published: May 2021

The Foods Editorial Office would like to update the error in the original published version [...]
Stability and Activity of the Antimicrobial Peptide Leg1 in Solution and on Meat and Its Optimized Generation from Chickpea Storage Protein
Authors: Heymich Marie-Louise , Srirangan Showmika , Pischetsrieder Monika
Published: May 2021

The antimicrobial peptide Leg1 (RIKTVTSFDLPALRFLKL) from chickpea legumin is active against spoilage bacteria, yeast, and mold. The present study tested its effectiveness under food storage conditions and examined options to obtain a food-grade agent. The minimum inhibitory concentration (MIC) of Leg1 against E. coli (62.5 µM) proved stable over seven days at 20 °C or 4 °C. It was not influenced by reduced pH (5.0 vs. 6.8), which is relevant in food such as meat. An incubation temperature of 20 °C vs. 37 °C reduced the MIC to 15.6/7.8 µM against E. coli/B. subtilis. With a minimum bactericidal concentration in meat of 125/15.6 µM against E. coli/B. subtilis, Leg1 is equivalently effective as nisin and 5000–82,000 times more active than sodium benzoate, potassium sorbate, or sodium nitrite. Replacing the counter-ion trifluoroacetate derived from peptide synthesis by the more natural alternatives acetate or chloride did not impair the activity of Leg1. As an alternative to chemical synthesis, an optimized protocol for chymotryptic hydrolysis was developed, increasing the yield from chickpea legumin by a factor of 30 compared to the standard procedure. The present results indicate that food-grade Leg1 could possibly be applicable for food preservation.
Building of an Internal Transcribed Spacer (ITS) Gene Dataset to Support the Italian Health Service in Mushroom Identification
Authors: Giusti Alice , Ricci Enrica , Gasperetti Laura , Galgani Marta , Polidori Luca , Verdigi Francesco , Narducci Roberto , Armani Andrea
Published: May 2021

This study aims at building an ITS gene dataset to support the Italian Health Service in mushroom identification. The target species were selected among those mostly involved in regional (Tuscany) poisoning cases. For each target species, all the ITS sequences already deposited in GenBank and BOLD databases were retrieved and accurately assessed for quality and reliability by a systematic filtering process. Wild specimens of target species were also collected to produce reference ITS sequences. These were used partly to set up and partly to validate the dataset by BLAST analysis. Overall, 7270 sequences were found in the two databases. After filtering, 1293 sequences (17.8%) were discarded, with a final retrieval of 5977 sequences. Ninety-seven ITS reference sequences were obtained from 76 collected mushroom specimens: 15 of them, obtained from 10 species with no sequences available after the filtering, were used to build the dataset, with a final taxonomic coverage of 96.7%. The other 82 sequences (66 species) were used for the dataset validation. In most of the cases (n = 71; 86.6%) they matched with identity values ≥ 97–100% with the corresponding species. The dataset was able to identify the species involved in regional poisoning incidents. As some of these species are also involved in poisonings at the national level, the dataset may be used for supporting the National Health Service throughout the Italian territory. Moreover, it can support the official control activities aimed at detecting frauds in commercial mushroom-based products and safeguarding consumers.
Spoofing the Limit Order Book: A Strategic Agent-Based Analysis
Authors: Wang Xintong , Hoang Christopher , Vorobeychik Yevgeniy , Wellman Michael P.
Published: May 2021

We present an agent-based model of manipulating prices in financial markets through spoofing: submitting spurious orders to mislead traders who learn from the order book. Our model captures a complex market environment for a single security, whose common value is given by a dynamic fundamental time series. Agents trade through a limit-order book, based on their private values and noisy observations of the fundamental. We consider background agents following two types of trading strategies: the non-spoofable zero intelligence (ZI) that ignores the order book and the manipulable heuristic belief learning (HBL) that exploits the order book to predict price outcomes. We conduct empirical game-theoretic analysis upon simulated agent payoffs across parametrically different environments and measure the effect of spoofing on market performance in approximate strategic equilibria. We demonstrate that HBL traders can benefit price discovery and social welfare, but their existence in equilibrium renders a market vulnerable to manipulation: simple spoofing strategies can effectively mislead traders, distort prices and reduce total surplus. Based on this model, we propose to mitigate spoofing from two aspects: (1) mechanism design to disincentivize manipulation; and (2) trading strategy variations to improve the robustness of learning from market information. We evaluate the proposed approaches, taking into account potential strategic responses of agents, and characterize the conditions under which these approaches may deter manipulation and benefit market welfare. Our model provides a way to quantify the effect of spoofing on trading behavior and market efficiency, and thus it can help to evaluate the effectiveness of various market designs and trading strategies in mitigating an important form of market manipulation.
Us Mob Online: The Perils of Identifying as Indigenous on Social Media
Authors: Carlson Bronwyn , Kennedy Tristan
Published: May 2021

Social media is a highly valuable site for Indigenous people to express their identities and to engage with other Indigenous people, events, conversations, and debates. While the role of social media for Indigenous peoples is highly valued for public articulations of identity, it is not without peril. Drawing on the authors’ recent mixed-methods research in Australian Indigenous communities, this paper presents an insight into Indigenous peoples’ experiences of cultivating individual and collective identities on social media platforms. The findings suggest that Indigenous peoples are well aware of the intricacies of navigating a digital environment that exhibits persistent colonial attempts at the subjugation of Indigenous identities. We conclude that, while social media remains perilous, Indigenous people are harnessing online platforms for their own ends, for the reinforcement of selfhood, for identifying and being identified and, as a vehicle for humour and subversion.
Biomarkers in Different Asthma Phenotypes
Authors: Popović-Grle Sanja , Štajduhar Anamarija , Lampalo Marina , Rnjak Dina
Published: May 2021

Asthma is the most common respiratory disease. It has multiple phenotypes thatcan be partially differentiated by measuring the disease’s specific characteristics—biomarkers. The pathogenetic mechanisms are complex, and it is still a challenge to choose suitable biomarkers to adequately stratify patients, which became especially important with the introduction of biologicals in asthma treatment. Usage of biomarkers and an understanding of the underlying pathobiological mechanisms lead to the definition of endotypes. Asthma can be broadly divided into two endotypes, T2-high and T2-low. The right combination of various biomarkers in different phenotypes is under investigation, hoping to help researchers and clinicians in better disease evaluation since theindividual approach and personalized medicine are imperative. Multiple biomarkers are superior to a single biomarker.
Quantification of Phenotypic Variability of Lung Disease in Children with Cystic Fibrosis
Authors: Stahl Mirjam , Steinke Eva , Mall Marcus A.
Published: May 2021

Cystic fibrosis (CF) lung disease has the greatest impact on the morbidity and mortality of patients suffering from this autosomal-recessive multiorgan disorder. Although CF is a monogenic disorder, considerable phenotypic variability of lung disease is observed in patients with CF, even in those carrying the same mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene or CFTR mutations with comparable functional consequences. In most patients with CF, lung disease progresses from childhood to adulthood, but is already present in infants soon after birth. In addition to the CFTR genotype, the variability of early CF lung disease can be influenced by several factors, including modifier genes, age at diagnosis (following newborn screening vs. clinical symptoms) and environmental factors. The early onset of CF lung disease requires sensitive, noninvasive measures to detect and monitor changes in lung structure and function. In this context, we review recent progress with using multiple-breath washout (MBW) and lung magnetic resonance imaging (MRI) to detect and quantify CF lung disease from infancy to adulthood. Further, we discuss emerging data on the impact of variability of lung disease severity in the first years of life on long-term outcomes and the potential use of this information to improve personalized medicine for patients with CF.
Genomic Association between SNP Markers and Diseases in the “Curraleiro Pé-Duro” Cattle
Authors: Freitas Thais Miranda Silva , Dias Juliana Moraes , Guimarães Luanna Kim Pires , Peixoto Sáudio Vieira , Silva Rayanne Henrique Santana da , Badr Kareem Rady , Moura Maria Ivete , Carmo Adriana Santana do , Landi Vincenzo , Fioravanti Maria Clorinda Soares
Published: May 2021

Susceptibility to diseases is inherited and can be transmitted between populations. Single-nucleotide polymorphism (SNPs) in genes related to immune response is associated with diseases in cattle. This study investigated SNPs in the genomic region of cytokines in 702 samples of Curraleiro Pé-Duro cattle and associated them with the occurrence of antibodies in brucellosis, leptospirosis, neosporosis, leukosis, infectious bovine rhinotracheitis (IBR), and bovine viral diarrhea (BVD) tests. DNA samples were evaluated by the kompetitive allele-specific polymerase chain reaction (KASP) method to identify polymorphisms. The gametic phase and SNP haplotypes were determined with the help of PHASE 2.1.1 software. Haplotypes were associated with serological results against Brucella abortus, Leptospira sp., Neospora caninum, leukosis, infectious rhinotracheitis, and BVD using univariate analysis followed by logistic regression. Haplotype 2 of TLR2 was present in 70% of the animals that tested positive for N. caninum infection. Haplotypes of TLR10 and TLR6 and IL10RA were more common in seronegative animals. Haplotypes related to the gene IL10RA were associated with animals negative to all infections. Curraleiro Pé-Duro cattle presented polymorphisms related to resistance to bacterial, viral, and N. caninum infections.
Molecular Composition of Heterochromatin and Its Contribution to Chromosome Variation in the Microtus thomasi/Microtus atticus Species Complex
Authors: Rovatsos Michail , Marchal Juan Alberto , Giagia-Athanasopoulou Eva , Sánchez Antonio
Published: May 2021

The voles of the Microtus thomasi/M. atticus species complex demonstrate a remarkable variability in diploid chromosomal number (2n = 38–44 chromosomes) and sex chromosome morphology. In the current study, we examined by in situ hybridization the topology of four satellite DNA motifs (Msat-160, Mth-Alu900, Mth-Alu2.2, TTAGGG telomeric sequences) and two transposons (LINE, SINE) on the karyotypes of nine chromosome races (i.e., populations with unique cytogenetic traits) of Microtus thomasi, and two chromosomal races of M. atticus. According to the topology of the repetitive DNA motifs, we were able to identify six types of biarmed chromosomes formed from either Robertsonian or/and tandem fusions. In addition, we identified 14 X chromosome variants and 12 Y chromosome variants, and we were able to reconstruct their evolutionary relations, caused mainly by distinct mechanisms of amplification of repetitive DNA elements, including the telomeric sequences. Our study used the model of the Microtus thomasi/M. atticus species complex to explore how repetitive centromeric content can alter from chromosomal rearrangements and can shape the morphology of sex chromosomes, resulting in extensive inter-species cytogenetic variability.
DRASTICAI, a New Index for Groundwater Vulnerability Assessment—A Portuguese Case Study
Authors: Albuquerque Teresa , Roque Natália , Rodrigues Joana , Antunes Margarida , Silva Catarina
Published: May 2021

Groundwater vulnerability assessment has become a useful tool for groundwater pollution prevention. Groundwater vulnerability maps provide useful data for protecting groundwater resources. Identification of agricultural patterns is an important issue for optimized land management. The watershed of the Tagus River is the backbone of this study. Naturtejo UNESCO Global Geopark, in the central interior of Portugal, corresponds to a rural area. Intensive agricultural practices showed an increasing trend in the last decades. The method that is most used internationally to assess vulnerability is the DRASTIC index. In this study, the DRASTICAI index is introduced. A new attribute—anthropogenic influence—is added here. Five levels of increasing vulnerability, from low to high, can be recognized here. The municipality of Idanha-a-Nova is most affected by intensive agricultural activities, showing spatial patterns of DRASTICAI with a clear influence of anthropogenic activities, with high needs for groundwater abstraction. A robust assessment of groundwater quality has a key role. Climate change scenarios and water scarcity are important issues in the coming years, and particularly in the studied area. Therefore, optimized groundwater management is essential to consider in policy-making strategies.
A New Set of Tools for the Generation of InSAR Visibility Maps over Wide Areas
Authors: Del Soldato Matteo , Solari Lorenzo , Novellino Alessandro , Monserrat Oriol , Raspini Federico
Published: May 2021

Multi-temporal Interferometric Synthetic Aperture Radar (MTInSAR) is a solid and reliable technique used to measure ground motion in many different environments. Today, the scientific community and a wide variety of users and stakeholders consider MTInSAR a precise tool for ground motion-related applications. The standard product of a MTInSAR analysis is a deformation map containing a high number of point-like measurement points (MP) which carry information on ground motion. The density of MPs is uneven, and they cannot be extracted continuously at large scale due to geometrical distortions and unfavourable landcover. It is a good practice to assess the feasibility of the interferometric analysis ahead of data processing. This technical note proposes a ready-to-use set of tools aimed at updating existing methods for modelling the effects of local topography and land cover on MTInSAR approaches. The goal of the tools is to provide InSAR experts and non-experts with a fast and automatic way to derive visibility maps, useful for pre-processing screening of a target area, and to forecast the expected density of MP over a specified area. Moreover, the visibility maps are a valid support for users to better understand the available standard and advanced interferometric results. Two workflows are proposed: the first generates the so-called Rindex map (Ri_m) to estimate the influence of topography on MP detection, the second is used to derive a land cover-calibrated Ri_m seen as a probabilistic model for MP detection (MPD_m). The proposed set of tools was applied in the context of the Alpine arc, whose climatic, morphological, and land cover characteristics represent a challenging environment for any interferometric approach.
Differences between the Sexes in the Relationship between Chronic Pain, Fatigue, and QuickDASH among Community-Dwelling Elderly People in Japan
Authors: Shimo Satoshi , Sakamoto Yuta , Amari Takashi , Chino Masaaki , Sakamoto Rie , Nagai Masanori
Published: May 2021

Chronic pain and fatigue have negative effects on the health, ADL, work, and hobbies of the elderly. As the proportion of people 65 years of age and older in the population increases, chronic pain and disability research regarding this group is receiving more consideration. However, little empirical evidence of the association between chronic pain, fatigue, and physical disability between the sexes is available. This study investigated the association between chronic pain, fatigue, and instrumental activities of daily living among community-dwelling elderly people by sex in Japan. Concerning the presence of chronic pain, 61% of males and 78% of females reported chronic pain, indicating that many elderly people living in the community suffer from chronic pain and fatigue on a daily basis. The number of sites of chronic pain was higher in females than in males (p = 0.016), with more chronic pain in the knees (p < 0.001) and upper arms (p = 0.014). Regarding chronic pain, males showed a higher correlation with QuickDASH-DS (rs = 0.433, p = 0.017) and QuickDASH-SM (rs = 0.643, p = 0.018) than females. Furthermore, fatigue also showed a higher correlation with QuickDASH-W (rs = 0.531, p = 0.003) in males than in females. These results indicate that the association between chronic pain, fatigue, and QuickDASH differed between the sexes among community-dwelling elderly people in Japan. A better understanding of the risk factors for elderly chronic pain and fatigue among sexes will facilitate the development of elderly healthcare welfare and policies.
Software “Pinxit”: Hail Magister Leonardo!
Authors: Zilberstein Gleb , Zilberstein Roman , Zilberstein Svetlana , Maor Uriel , Righetti Pier Giorgio
Published: May 2021

In the present report, we offer a novel way for studying (via optical and digital means) features in Renaissance and Leonardo’s (and of course any other painter who followed this canon) paintings, based on a software that separately recognizes white, red, green, blue colors and measures the intensity of single bright spots in canvasses. After mapping the distribution of individual colors, the software proposes a trajectory considering the different geometrical and topological aspects. What we propose here is not just a variant of known methods for discovering the color distribution in a painting; on the contrary, it represents a new way to find unknown parameters in any Renaissance painting. In addition, via multispectral and hyperspectral analyses and image processing, the developed software permitted us to monitor the decay of some pigments in these canvasses at macro- and microscopic levels.
Predicting of the Coronavirus Disease 2019 (COVID-19) Epidemic Using Estimation of Parameters in the Logistic Growth Model
Authors: Kartono Agus , Wahyudi Setyanto Tri , Setiawan Ardian Arif , Sofian Irmansyah
Published: May 2021

The COVID-19 pandemic was impacting the health and economy around the world. All countries have taken measures to control the spread of the epidemic. Because it is not known when the epidemic will end in several countries, then the prediction of the COVID-19 pandemic is a very important challenge. This study has predicted the temporal evolution of the COVID-19 pandemic in several countries using the logistic growth model. This model has analyzed several countries to describe the epidemic situation of these countries. The time interval of the actual data used as a comparison with the prediction results of this model was starting in the firstly confirmed COVID-19 cases to December 2020. This study examined an approach to the complexity spread of the COVID-19 pandemic using the logistic growth model formed from an ordinary differential equation. This model described the time-dependent population growth rate characterized by the three parameters of the analytical solution. The non-linear least-squares method was used to estimate the three parameters. These parameters described the rate growth constant of infected cases and the total number of confirmed cases in the final phase of the epidemic. This model is applied to the spread of the COVID-19 pandemic in several countries. The prediction results show the spread dynamics of COVID-19 infected cases which are characterized by time-dependent dynamics. In this study, the proposed model provides estimates for the model parameters that are good for predicting the COVID-19 pandemic because they correspond to actual data for all analyzed countries. It is based on the coefficient of determination, R2, and the R2 value of more than 95% which is obtained from the non-linear curves for all analyzed countries. It shows that this model has the potential to contribute to better public health policy-making in the prevention of the COVID-19 pandemic.
Knowledge, Emotions and Stressors in Front-Line Healthcare Workers during the COVID-19 Outbreak in Mexico
Authors: Hernández-Díaz Yazmín , Genis-Mendoza Alma Delia , Fresán Ana , González-Castro Thelma Beatriz , Tovilla-Zárate Carlos Alfonso , Juárez-Rojop Isela Esther , López-Narváez María Lilia , Martínez-Magaña José Jaime , Nicolini Humberto
Published: May 2021

The aim of this study was to explore the knowledge, emotions and perceived stressors by healthcare workers who were in contact with infected patients during the COVID-19 outbreak. An online cross-sectional survey was applied. Data were collected from N = 263 healthcare workers in Tabasco State, Mexico. We developed and administered a questionnaire, which consisted of sociodemographic characteristics, plus four sections. The sections evaluated were (1) knowledge of COVID-19; (2) feelings/emotions during the COVID-19 outbreak; (3) factors that caused stress and (4) factors that helped to reduce stress. Surveyed individuals were divided into three groups: physicians, nurses and other healthcare workers. When we evaluated their knowledge of COVID-19 we observed that the majority of healthcare workers in the three groups reported that they knew about COVID-19. Physicians indicated that they felt insecure about practicing their profession (62.5%) due to the high risk of being in contact with SARS-CoV-2. With regards to stressor factors, the risk of transmitting COVID-19 to their families was the main factor causing moderate to high stress (95.4%). Finally, we found that “your profession puts your life at risk” was the only factor associated with feeling nervous and scared (PR: 3.15; 95% CI: 1.54–6.43). We recommended health education campaigns, introductory courses on COVID-19 and other infectious diseases, management protocols and the provision of protection equipment to health workers in order to reduce personal and professional fears of contagion and to improve the health system in Mexico when facing epidemics.
How Social Media Comments Inform the Promotion of Mask-Wearing and Other COVID-19 Prevention Strategies
Authors: Keller Sarah N. , Honea Joy C. , Ollivant Rachel
Published: May 2021

Current COVID-19 messaging efforts by public health departments are primarily informational in nature and assume that audiences will make rational choices in compliance, contradicting extensive research indicating that individuals make lifestyle choices based on emotional, social, and impulsive factors. To complement the current model, audience barriers to prevention need to be better understood. A content analysis of news source comments in response to daily COVID-19 reports was conducted in Montana, one of the states expressing resistance to routine prevention efforts. A total of 615 Facebook comments drawn from Montana news sources were analyzed using the Persuasive Health Message Framework to identify perceived barriers and benefits of mask-wearing. A majority (63%) of comments expressed barriers, the most common of which were categorized as either misinformation about the virus or conspiracy theories. Benefits (46%) of mask-wearing were articulated as benefits to loved ones or people in one’s community or saving hospital space. This paper analyzes the implications of low perceived threat accompanied by low perceived efficacy of mask-wearing to make recommendations for future prevention efforts.
Food Insecurity: Is It a Threat to University Students’ Well-Being and Success?
Authors: Ahmad Nor Syaza Sofiah , Sulaiman Norhasmah , Sabri Mohamad Fazli
Published: May 2021

Food insecurity is a growing concern among university students. The high prevalence of food insecurity is a threat to students’ health and success. Therefore, this study aims to determine an association between food security status, psychosocial factors, and academic performance among university students. A total of 663 undergraduate students in seven randomly selected faculties in Universiti Putra Malaysia participated in this study. An online survey was conducted to obtain demographic and socioeconomic characteristics, food security status (six-item USDA; food security survey module, FSSM), psychosocial factors (depression, anxiety and stress scale, DASS-21) and academic performance. Among the abovementioned participating students, 32.4% are male. About 62.8% reported to have experienced food insecurity. Binary logistic regression revealed that students whose fathers were working (AOR = 6.446, 95% CI: 1.22, 34.01) came from low- (AOR = 14.314, 95% CI: 1.565, 130.954) and middle-income groups (AOR = 15.687, 95% CI: 1.720, 143.092), and those receiving financial aid (AOR = 2.811, 95% CI: 1.602, 4.932) were associated with food insecurity. Additionally, food insecurity students were less-likely reported, with CGPA ≥ 3.7 (AOR = 0.363, 95% CI: 1.22–34.014). Food insecurity respondents had higher odds for stress (AOR = 1.562, 95% CI: 1.111, 2.192), anxiety (AOR = 3.046, 95% CI: 2.090, 4.441), and depression (AOR = 2.935, 95% CI: 2.074, 4.151). The higher institutions should identify students with food insecurity problems and future intervention programs need to be conducted to combat food insecurity among students, thus yielding benefits to their health and success.
Influence of Parental Health Literacy on Change over Time in the Oral Health of American Indian Children
Authors: Brega Angela G. , Johnson Rachel L. , Jiang Luohua , Wilson Anne R. , Schmiege Sarah J. , Albino Judith
Published: May 2021

In cross-sectional studies, parental health literacy (HL) is associated with children’s oral health. It is unclear, however, whether HL influences pediatric outcomes. We examined the relationship of HL with change over time in parental oral health knowledge, beliefs, and behaviors, as well as pediatric oral health outcomes. We used longitudinal data from a study designed to reduce dental decay in American Indian children (N = 579). At baseline and annually for three years, parents answered questions assessing HL; oral health knowledge, beliefs, and behaviors; and pediatric oral health status. The number of decayed, missing, and filled tooth surfaces (dmfs) was computed based on annual dental evaluations. Linear mixed models showed that HL was significantly associated with all constructs, except dmfs, at their reference time points and persistently across the three-year study period. HL predicted change over time in only one variable, parents’ belief that children’s oral health is determined by chance or luck. HL is strongly associated with oral health knowledge, beliefs, behaviors, and status prospectively but is not a key driver of change over time in these oral health constructs.
Using Spatial Pattern Analysis to Explore the Relationship between Vulnerability and Resilience to Natural Hazards
Authors: Sung Chien-Hao , Liaw Shyue-Cherng
Published: May 2021

This research aims to explore the spatial pattern of vulnerability and resilience to natural hazards in northeastern Taiwan. We apply the spatially explicit resilience-vulnerability model (SERV) to quantify the vulnerability and resilience to natural hazards, including flood and debris flow events, which are the most common natural hazards in our case study area due to the topography and precipitation features. In order to provide a concise result, we apply the principal component analysis (PCA) to aggregate the correlated variables. Moreover, we use the spatial autocorrelation analysis to analyze the spatial pattern and spatial difference. We also adopt the geographically weighted regression (GWR) to validate the effectiveness of SERV. The result of GWR shows that SERV is valid and unbiased. Moreover, the result of spatial autocorrelation analysis shows that the mountain areas are extremely vulnerable and lack enough resilience. In contrast, the urban regions in plain areas show low vulnerability and high resilience. The spatial difference between the mountain and plain areas is significant. The topography is the most significant factor for the spatial difference. The high elevation and steep slopes in mountain areas are significant obstacles for socioeconomic development. This situation causes consequences of high vulnerability and low resilience. The other regions, the urban regions in the plain areas, have favorable topography for socioeconomic development. Eventually, it forms a scenario of low vulnerability and high resilience.
Implementation Process of General Land-Use Planning and Its Adjustment—A Case Study of Rongchang District in Chongqing, China
Authors: Li Lingli , Wang Jinjie , Yang Chaoxian , Wei Chaofu
Published: May 2021

General land-use planning has a critical role and a guiding significance for economic and regional social development. To increase the ability of planning to cope with regional economic changes in an orderly manner and to defend the legal status of the planning guidance role, this article takes Rongchang District as a case study. This study combines GIS spatial analysis to select speed indicators, the center of gravity offset theory, and the spatial fit model and analyses the implementation process and the adjustment situation of planning from the perspectives of ‘quantity’, ‘time’, and ‘space’. The main results are as follows: (1) The completion rate of cultivated land and the surplus rate of urban land show that planning can effectively guide the direction of land use, with the results of 101.9% and 15%, respectively. The difficulty of planning implementation lies in the control of rural residential land because the actual annual average withdrawal rate of rural residential land is less than one-third of the planned rate, with an actual withdrawal area of 97.22 hm2 per year on average. (2) The results of the spatial coincidence degree and the barycentric offset angle demonstrate that planning plays a prominent role in guiding the direction of land use, although deviations remain between planned and actual land-use demand, with values ranging from 0.9 to 1 and an angle of less than 30° between the implementation process and the target year. (3) From 2013 to 2015, the planning of the study area was adjusted 32 times with an area of 2301.7 hm2. This finding indicates that planning is characterized by frequent disorder and that the gap between land use and planning is alleviated at the cost of the planning authority. (4) The degree of the coincidence between the adjusted plan and the land-use change data decreased year by year, reaching 0.99 two years after implementation of the plan, which is closest to the actual land demand. Thus, general land-use planning can guide the direction of land use to some extent, and the adjustment of planning can alleviate the contradictions of land-use demand under the changes of economic development, but the disorder ignores the legal status of planning. Making regular dynamic adjustments to the plan can provide ideas for planning compilation and revision while maintaining economic benefits and guiding functions without losing legal status.
Reliability and Validity of the ONAPS Physical Activity Questionnaire in Assessing Physical Activity and Sedentary Behavior in French Adults
Authors: Charles Marc , Thivel David , Verney Julien , Isacco Laurie , Husu Pauliina , Vähä-Ypyä Henri , Vasankari Tommi , Tardieu Michèle , Fillon Alicia , Genin Pauline , Larras Benjamin , Chabanas Bruno , Pereira Bruno , Duclos Martine
Published: May 2021

This study was conducted to assess the validity and reliability of a new questionnaire, the ONAPS-PAQ, developed to assess physical activity (PA) and sedentary behaviors (SB) in the general population. A total of 137 healthy adults aged 18 to 69 years were included. Following completion of two physical activity questionnaires (ONAPS-PAQ and GPAQ, the Global physical activity questionnaire) to study concurrent validity, participants wore an accelerometer (UKK-RM42) for 7 days to study criterion validity. A subsample (n = 36) also completed a 7-day-interval test–retest protocol to assess its reliability. Reliability was tested by the intraclass correlation coefficient (ICC) and Kappa coefficient; concurrent and criterion validity by the Spearman correlation coefficient (ρ) and Bland-Altman plot analyses. The ONAPS-PAQ showed good reliability (ICC = 0.71–0.98; Kappa = 0.61–0.99) and concurrent validity (ρ = 0.56–0.86), but only poor criterion validity (ρ = 0.26–0.41), and wide limits of agreement. Self-reported and accelerometer-measured SB were better correlated with ONAPS-PAQ than GPAQ (0.41 vs. 0.26, respectively) and medians were comparable, whereas the GPAQ underestimated SB (SBacc = 481 (432–566), SBONAPS = 480 (360–652), SBGPAQ = 360 (240–540) min·day−1; median (q1-q3)). The ONAPS-PAQ provides good reliability and acceptable validity for the measurement of PA and SB and seems to provide a better assessment of SB than GPAQ.
Malignant Germ Cell Tumors and Their Precursor Gonadal Lesions in Patients with XY-DSD: A Case Series and Review of the Literature
Authors: Steinmacher Sahra , Brucker Sara Y. , Kölle Andrina , Krämer Bernhard , Schöller Dorit , Rall Katharina
Published: May 2021

The risk of gonadal germ cell tumors is increased over the lifetime of patients with XY-disorders of sex development (XY-DSD). The aim of this study was to evaluate clinical features and histopathological outcome after gonadectomy in patients with XY-DSD to assess the risk of malignant transformation to gonadal germ cell tumors. Thirty-five women treated for XY-DSD at our hospital between 2003 and 2020 were enrolled in this study. Twenty-seven (77%) underwent prophylactic gonadectomy, 10 (29%) at our department and 17 (48%) at external hospitals. Eight (23%) patients didn’t receive gonadectomy. Of the patients who underwent a surgical procedure at our hospital, two patients were diagnosed with a unilateral seminoma, one patient with a bilateral and one patient with a unilateral Sertoli cell adenoma. According to these findings, preventive gonadectomy in patients with XY-DSD should be taken into consideration. Guidelines concerning the necessity of gonadectomy to avoid malignant transformation are still lacking. The risk of malignant germ cell tumors from rudimentary gonads has not been investigated sufficiently to date, as it is mostly based on case series due to the rarity of the condition. In our study we retrospectively analyzed patients who partly underwent bilateral gonadectomy, aiming to fill this gap. Concerning the ideal point of time for gonadectomy, further studies with a higher number of patients are needed.
Hospital Employees’ Well-Being Six Months after the COVID-19 Outbreak: Results from a Psychological Screening Program in Italy
Authors: Lamiani Giulia , Borghi Lidia , Poli Silvia , Razzini Katia , Colosio Claudio , Vegni Elena
Published: May 2021

The COVID-19 outbreak has taken a heavy toll on the mental well-being of healthcare workers. This study aims to describe a psychological screening program developed at a large University Hospital in Milan, Italy, and assess the psychological outcomes of employees and associated factors. A survey was electronically conducted among hospital employees between July and October 2020. Sociodemographic data, information about COVID-19 experience and three scales assessing anxiety (STAI-Y1), depression (HAM-D) and post-traumatic stress disorder (PCL-5) were collected. A total of 308 employees (80% women; mean age 45.1 years) responded: 16% physicians, 68% other healthcare professionals, and 16% administrative staff. Employees reported moderate/severe symptoms of anxiety (23%), depression (53%), and post-traumatic stress disorder (40%). At multivariate logistic regression analysis, having suffered a loss for COVID-19 in the personal context was independently associated with higher risk of moderate/severe anxiety (OR = 2.40; 95% CI 1.16–4.98), being female was associated with higher risk of moderate/severe depression (OR = 2.82; 95% CI 1.43–5.59), and having had a family member affected by COVID-19 was associated with higher risk of moderate/severe post-traumatic stress disorder (OR = 2.75; 95% CI 1.01–7.48). COVID-19 personal experience may have a profound impact on hospital workers’ mental health and should be considered in supportive interventions.
Differences in Workplace Risk Perception between Foreign-Born and First-Generation Mexican American Construction Workers
Authors: Ibarra-Mejía Gabriel , Gómez-Bull Karla Gabriela , Vargas-Salgado María Marisela
Published: May 2021

Risk perception is used to quantify risks in the industry and is influenced by different socio-demographic variables. This work aims to determine significant differences in the risk perception between Mexican American migrants and first-generation Mexican American construction workers. This study used a sample of 112 construction workers. A guided questionnaire was applied to collect socio-demographic information. For workplace risk behaviors, we used a 21-item questionnaire adapted from the previous instrument. Each question asked the participant’s perception of the frequency with which they carried out risky activities during routine work activities and the severity of the possible injuries, using a five-level Likert scale. Then, an inferential analysis was carried out using analysis of variance (ANOVA). The main results highlight that time of residence in the United States had a significant influence (p = 0.012) on risk perception in the surveyed construction workers. On the other hand, the age and time they have been working for the organization did not significantly influence risk perception. Finally, risk perception can vary in construction workers according to different variables. It is essential to investigate the factors that influence it, to prevent risky behaviors that can lead to accidents.
The Identification and Referral to Improve Safety Programme and the Prevention of Intimate Partner Violence
Authors: Akbari Amir Reza , Alam Benyamin , Ageed Ahmed , Tse Cheuk Yin , Henry Andrew
Published: May 2021

Introduction: Intimate Partner Violence (IPV) is a global epidemic which 30% of women experience world-wide. Domestic violence has serious health consequences, with an estimated cost of 1.7 billion annually to the NHS. However, healthcare professionals remain uncertain on how to manage IPV. In 2007, the Identification and Referral to Improve Safety (IRIS) was introduced within primary care to address this shortcoming. The aim of this project is to analyse the impact of IRIS, whilst discussing the extension into secondary care. Materials and Methods: A literature review was conducted using PubMed, Cochrane Library and Google scholar. The official IRIS publication list for randomized controlled trial data. Results: General practices with IRIS displayed a threefold increase in the identification of IPV and sevenfold increase in referrals. IRIS is cost-effective and under the NICE threshold of £20,000 per quality-adjusted life year gained. Additionally, a systematic review illustrated that one in six women presenting to the fracture clinic experienced IPV within the last year. Conclusions: The implementation of IRIS into general practice proved to be cost-effective. Orthopaedic fracture clinics are at the forefront of dealing with IPV, and therefore an adapted IRIS programme within this setting has potential in the prevention of IPV.