bluuebunny/crossref_metadata_2025 huggingface dataset:
DENTAL IMPLANT OPERATIONS PERFORMED AT GAZI UNIVERSITY FACULTY OF DENTISTRY DEPARTMENT OF ORAL AND MAXILLOFACIAL SURGERY FOR THE LAST SIX YEARS; PREVALANCE AND DEMOGRAPHIC DISTRIBUTION
Authors: Hürmüzlü Mustafa Kenan , Mollaoğlu Nur
Published: December 2024

The main purpose of dental implant treatments is to provide functional integrity, which is important for the oral health of patients who have lost their teeth, as well as to eliminate aesthetic and psychological problems. Thus, demographic information to be provided together with the retrospective studies performed in areas with high patient density forms a basis for other parameters to be used in the evaluation of the success criteria of dental implants. For this purpose, in our study, total of 1892 cases among 7345 cases who received implant treatment at Gazi University Faculty of Dentistry, Department of Oral and Maxillofacial Surgery between January 2017 and June 2022 was examined retrospectively according to years, gender, age, dental regions and tooth numbers. Among 1892 patients who underwent implant application, it was determined that female patients received more implant treatment than male patients by 51.7%. In addition, it was determined that the lower jaw and maxilla posterior regions were the most implanted regions. It was also observed that the most implanted age range was between the ages of 50 and 59 years (the 5th decade) by 31.1%. Looking at the monthly average, the most dental implant treatment was done in 2019 before the pandemic started.
Investigation of Antifungal Effects of Different Remineralization Agents on Salivary Candida amount in children with Early Childhood Caries
Authors: Eren Giray Figen , Güven Özşahin Ceren , Topcuoğlu Nursen , Kargul Betul
Published: December 2024

Objectives: In recent years, Candida has been associated with dental caries in children. The association of Candida albicans with the onset of ECC is well known. In addition to mutans streptococci and lactobacilli, Candida spp. is frequently present in the oral cavity of children with ECC. The purpose of this study was to compare different remineralization agents for Candida count in children with Severe Early Childhood Caries (S-ECC).

Materials and Methods: Fifty-four healthy children aged 3 to 5 years, diagnosed with S-ECC, were examined, and 21 candida-positive children were included in the study. Children were randomly assigned to 3 groups; 500 ppm NaF toothpaste (Control) group; 10% CPP-ACP group and CaGP and 12% Xylitol group. Oral hygiene training was given to the children and they were told to use remineralization agents 3 times a day for 3-5 min for 2 weeks. Unstimulated saliva was quantitatively cultured for Candida counts. The number of colonies of Candida species was determined at the baseline, 2nd week, 1st and 4th months. All analyses were performed with SPSS statistics version 23. A p-value of less than 0.05 was considered statistically significant.
Results: A statistically significant difference was found between baseline and 1st and 4th month Candida count in CaGP + 12% Xylitol group (p 0,05).
Conclusions: These results suggest that remineralization agents can reduce the count of Candida, thus it can be effective in caries management.
Genre et corps dans 'Crépuscule du tourment' de Léonora Miano : entre fiction et frictions
Authors: Molina Romero Mª Carmen
Published: December 2024

Crépuscule du tourment, de l’écrivaine franco-camerounaise Léonora Miano, nous offre un riche terrain d’analyse du corps et du genre féminin au croisement des actuels enjeux de la femme africaine et afrodescendante, en contexte francophone. À quatre voix, les narratrices égrènent les f(r)ictions de leurs cor(p)sages, à travers leurs vécus de corps-mémoire, de corps-désirant, de corps-social ou de corps-maternel. Avec ce quatrain textuel, Miano célèbre une poétique de la relation hors lisières, permettant le contact et la perméabilité, sans catégories, déconstruisant les « plis » corporels acquis par atavisme.
Le monde ourlé et le monde liseré
Authors: Westphal Bertrand
Published: December 2024

L’article explore la notion de lisière comme métaphore des frontières et des transitions dans la pensée philosophique et dans l’expression linguistique et littéraire. Il remet en question l’idée binaire d’une frontière qui serait soit fermée, soit ouverte, en proposant un modèle plus nuancé, symbolisé par la porte entrebâillée. À travers l’analyse plurlinguistique de plusieurs concepts et l’analyse et référence à divers œuvres littéraires et auteurs (comme Charles Baudelaire, María Zambrano ou Michel Tournier), l’article montre que les zones liminaires, ou interstitielles, sont des espaces de rencontre et de dialogue entre le même et l’autre. Ces zones offrent des possibilités infinies d’échange, de transformation et d’altérité, en opposition à l’immobilisme des frontières fermées. Cet article appelle ainsi à repenser les limites comme des espaces de connexion plutôt que de division.
DOKUSUZ YÜZEYLERİN BİYOMEDİKAL ALANDA KULLANIMLARI VE KARAKTERİZASYON YÖNTEMLERİ
Authors: Altıntaş Fatma , Koluman Ahmet
Published: December 2024

Teknolojik gelişmeler ve artan ihtiyaçlar, malzeme bilimi alanında önemli yeniliklere yol açmıştır. Tekstil endüstrisinin önemli bir alt dalı olan dokusuz yüzey malzemeler, biyomedikal alanda son yıllarda büyük ilgi gören ve geniş bir uygulama yelpazesine sahip önemli materyallerdir. Dokusuz yüzeyler, geleneksel dokuma veya örme teknikleri yerine lifleri doğrudan bir araya getirme veya bağlama yöntemleri ile üretilen, esnek, hafif ve ekonomik malzemelerdir. Bu malzemeler, üretim sürecindeki düzensiz lif yerleşimi ve çeşitli bağlama yöntemleri sayesinde düşük maliyetli, hafif, esnek ve hızlı üretilebilir olma avantajına sahiptir. Yüksek dayanıklılık, düşük ağırlık ve yüksek hava geçirgenliği gibi özellikleriyle dokusuz yüzeyler, yara örtüsü, ilaç iletimi, hijyen ürünleri ve biyolojik sinyal takibi gibi alanlarda etkili çözümler sunmaktadır. Dokusuz yüzey malzemelerin geniş kullanım alanları, fiziksel, mekanik ve kimyasal özelliklerinin doğru bir şekilde karakterize edilmesini gerektirmektedir. Bu karakterizasyon, malzemenin performansını, kalitesini ve uygulama potansiyelini belirleme açısından kritik bir rol oynamaktadır. Dokusuz yüzeylerin karakterizasyon yöntemleri, malzemenin yapısını, mukavemetini, geçirgenliğini, emme kapasitesini ve diğer önemli özelliklerini değerlendirme sürecini içermektedir. Bu makalede, dokusuz yüzey malzemelerin biyomedikal alanlarına odaklanılarak, bu malzemelerin karakterizasyon yöntemlerine dair kapsamlı bir inceleme sunmaktadır. Dokusuz yüzeylerin özelliklerini belirleme amacıyla kullanılan çeşitli karakterizasyon yöntemleri, literatürdeki güncel araştırmalara dayanarak detaylı bir şekilde ele alınmıştır.
MQTT Protocol in Smart Home Environments: Principles of Operation and Application
Authors: Begović Tijana , Čabarkapa Vasilije , Ivković Milica , Popović Božidar
Published: December 2024

Internet of Things as a revolutionary concept in technology of modern days has led to the popularization of “smart” things. It introduces low-cost and reliable solutions to provide independent operations of devices and machines. Smart home systems have become one of the most important implementations as they significantly improve the quality of people’s lives. Since communication plays a key role in these systems, this article provides insights into Message Queuing Telemetry Transport protocol application in smart home systems. Although it is not the only protocol used, MQTT stands out in terms of reliability, efficiency, and simplicity. The article provides major MQTT characteristics, advantages and its application in a particular smart home system for ambient parameters monitoring and control. The system integrates NodeMCU based sensor node with mobile and web applications via MQTT protocol. Results of the performance analysis of MQTT use in this system are given. Tests have shown great connection establishment speed, a high percentage of successfully sent messages, and a large number of messages sent per minute. Thanks to the flexibility of the MQTT protocol, the system is easy to upgrade and expand.
A System for Remotely Monitoring and Controlling Temperature within an Egg Artificial Incubator
Authors: Popović Nataša , Popović Božidar
Published: December 2024

According to a report by the Food and Agriculture Organization of the United Nations, poultry meat is the leading contributor to global growth in total meat production. This growth is facilitated by the short production cycle of poultry, advancements in genetics, animal healthcare, feeding methods, breeding techniques, and improved environmental conditions, enabling producers to adapt quickly to market demands. Proper hatching practices are critical to maximizing the number of healthy chicks and minimizing their mortality rate. There are two primary methods of hatching: natural incubation, where hens incubate eggs by sitting on them, and artificial incubation, which uses incubators. In artificial incubation, monitoring and controlling key environmental factors, particularly temperature and humidity, are essential. Maintaining the incubator's temperature within an optimal range is crucial, with literature recommending a range of 37°C to 38°C and an ideal temperature of 37.8°C. This paper introduces a system for remotely monitoring and controlling temperature within an artificial incubator. The system integrates hardware and software based on the Internet of Things (IoT) framework. For this purpose, a proportional-integral-derivative (PID) controller is designed to maintain the desired temperature, with temperature data stored in a database and accessible online. The proposed system offers a cost-effective yet highly efficient solution, primarily designed for small-scale hatcheries. With modifications, it can be adapted for broader agricultural applications, including greenhouses, silos, and stables. By contributing to digital agriculture, the system supports sustainable farming practices, which are essential for the future of agriculture.
Phenotypic impact of individual conserved neuronal microexons and their master regulators in zebrafish
Authors: Lopez-Blanch Laura , Rodríguez-Marin Cristina , Mantica Federica , Iñiguez Luis P , Permanyer Jon , Kita Elizabeth M , Mackensen Tahnee , Codina-Tobias Mireia , Romero-Ferrero Francisco , Fernandez-Albert Jordi , Cuadrado Myriam , Bustelo Xosé R , de Polavieja Gonzalo G , Irimia Manuel
Published: December 2024

Microexons exhibit striking evolutionary conservation and are subject to precise, switch-like regulation in neurons, orchestrated by the splicing factors
Srrm3
and
Srrm4
. Disruption of these regulators in mice leads to severe neurological phenotypes, and their misregulation is linked to human disease. However, the specific microexons involved in these phenotypes and the effects of individual microexon deletions on neurodevelopment, physiology, and behavior remain poorly understood. To explore this, we generated zebrafish lines with deletions of 18 individual microexons, alongside
srrm3
and
srrm4
mutant lines, and conducted comprehensive phenotypic analyses. We discovered that while loss of
srrm3
, alone or together with
srrm4
, resulted in significant alterations in neuritogenesis, locomotion, and social behavior, individual microexon deletions typically produced mild or no noticeable effects. Nonetheless, we identified specific microexons associated with defects in neuritogenesis (
evi5b
,
vav2
,
itsn1
,
src
) and social behavior (
vti1a
,
kif1b
). Additionally, microexon deletions triggered coordinated transcriptomic changes in neural pathways, suggesting the presence of molecular compensatory mechanisms. Our findings suggest that the severe phenotypes caused by
Srrm3/4
depletion arise from the combined effects of multiple subtle disruptions across various cellular pathways, which are individually well-tolerated.
A new pipeline SPICE identifies novel JUN-IKZF1 composite elements
Authors: Li Peng , Pulugulla Sree , Das Sonali , Oh Jangsuk , Spolski Rosanne , Lin Jian-Xin , Leonard Warren J
Published: December 2024

Transcription factor partners can cooperatively bind to DNA composite elements to augment gene transcription. Here, we report a novel protein-DNA binding screening pipeline, termed Spacing Preference Identification of Composite Elements (SPICE), that can systematically predict protein binding partners and DNA motif spacing preferences. Using SPICE, we successfully identified known composite elements, such as AP1-IRF composite elements (AICEs) and STAT5 tetramers, and also uncovered several novel binding partners, including JUN-IKZF1 composite elements. One such novel interaction was identified at CNS9, an upstream conserved noncoding region in the human IL10 gene, which harbors a non-canonical IKZF1 binding site. We confirmed the cooperative binding of JUN and IKZF1 and showed that the activity of an IL10-luciferase reporter construct in primary B and T cells depended on both this site and the AP1 binding site within this composite element. Overall, our findings reveal an unappreciated global association of IKZF1 and AP1 and establish SPICE as a valuable new pipeline for predicting novel transcription binding complexes.
Economics of Fieldpea (Pisum sativum L.) as Influenced by Phosphorus Levels and Bio-fertilizers in Central Plains of Uttar Pradesh, India
Authors: Katiyar Drishty , Kumar Ravindra , Yadav Arushi , Prajapati Bimlesh Kumar , Kushwaha Raghvendra Kumar
Published: December 2024

A field experiment was conducted at the student instructional farm of CSAUA&T, Kanpur, during the Rabi season of 2021-22 and 2022-23. Sandy loam was the texture of the experimental soil. There are twelve treatment involving combinations of phosphorus and biofertilizers with three replication of factorial randomized block design (FRBD). A fieldpea variety IPFD 6-3 was planted according to recommended agronomic practices. The results of these studies indicate that fieldpea cultivation over a two-year period is consistent with T12 (P90 R1 PSB1), the most economically effective treatment and also recorded the highest economics parametric values i.e., maximum cost of cultivation of ₹39006 & ₹39751, gross return of ₹ 106055 & ₹118535, net return of ₹67049 & ₹ 78784 and benefit to cost ratios were 1.72 & 1.98 followed by the treatment T11.
Minimizing Process Water and Energy Consumption in Styrene Production by Ethylbenzene Dehydrogenation
Authors: Najib Muchammad Ilham , Hestiawan Felicia , Pratiwi Amelia , Pangayom Lintang Bagas
Published: December 2024

Styrene is a crucial unsaturated aromatic monomer with a wide range of industrial applications. Styrene production faces several problems where the water supply and energy usage are keep increasing. Process modifications were implemented to minimize process water and to optimize the energy consumption. The modification uses Aspen HYSYS simulation by replacing coolers and heaters with heat exchanger and implementing water recycling system. Aspen HYSYS simulations show these changes reduce water usage by 89.8% and significantly decrease energy consumption up to 54.69%. This modification shows the water and energy usage have been significantly reduced than the basic process. Copyright © 2024 by Authors, Published by Universitas Diponegoro and BCREC Publishing Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0).
Deep learning‐based auto‐segmentation of clinical target volumes for radiotherapy treatment of cervical cancer
Authors: Ma Chen‐Ying , Zhou Ju‐Ying , Xu Xiao‐Ting , Guo Jian , Han Miao‐Fei , Gao Yao‐Zong , Du Hui , Stahl Johannes N. , Maltz Jonathan S.
Published: November 2021

Objectives

Because radiotherapy is indispensible for treating cervical cancer, it is critical to accurately and efficiently delineate the radiation targets. We evaluated a deep learning (DL)‐based auto‐segmentation algorithm for automatic contouring of clinical target volumes (CTVs) in cervical cancers.

Methods

Computed tomography (CT) datasets from 535 cervical cancers treated with definitive or postoperative radiotherapy were collected. A DL tool based on VB‐Net was developed to delineate CTVs of the pelvic lymph drainage area (dCTV1) and parametrial area (dCTV2) in the definitive radiotherapy group. The training/validation/test number is 157/20/23. CTV of the pelvic lymph drainage area (pCTV1) was delineated in the postoperative radiotherapy group. The training/validation/test number is 272/30/33. Dice similarity coefficient (DSC), mean surface distance (MSD), and Hausdorff distance (HD) were used to evaluate the contouring accuracy. Contouring times were recorded for efficiency comparison.

Results

The mean DSC, MSD, and HD values for our DL‐based tool were 0.88/1.32 mm/21.60 mm for dCTV1, 0.70/2.42 mm/22.44 mm for dCTV2, and 0.86/1.15 mm/20.78 mm for pCTV1. Only minor modifications were needed for 63.5% of auto‐segmentations to meet the clinical requirements. The contouring accuracy of the DL‐based tool was comparable to that of senior radiation oncologists and was superior to that of junior/intermediate radiation oncologists. Additionally, DL assistance improved the performance of junior radiation oncologists for dCTV2 and pCTV1 contouring (mean DSC increases: 0.20 for dCTV2, 0.03 for pCTV1; mean contouring time decrease: 9.8 min for dCTV2, 28.9 min for pCTV1).

Conclusions

DL‐based auto‐segmentation improves CTV contouring accuracy, reduces contouring time, and improves clinical efficiency for treating cervical cancer.
Ion‐Conductive Polytitanosiloxane Networks Enable a Robust Solid‐Electrolyte Interface for Long‐Cycling Lithium Metal Anodes
Authors: Zhong Yuan , Huang Peng , Yan Wen , Su Zhong , Sun Chuang , Xing Yimin , Lai Chao
Published: November 2021

Despite a high‐energy density and low reduction potential, the use of Li metal batteries is hampered by their insufficient electrochemical sustainability, which mainly stems from the lack of a reliable solid‐electrolyte interphase (SEI). In this study, a robust SEI connected by polytitanosiloxane (PTS) is constructed via the in situ condensation reaction between tetraethyl orthosilicate/tetraethyl orthotitanate (TEOS/TEOT) electrolyte additives and the Li anode. In PTS, the Si‒O‒Si bonds, which have a low ion diffusion barrier, can provide an Li+ transport pathway to ensure regular Li deposition. Moreover, the 3D crosslinked PTS skeleton with strong Si‒O‒Ti linkages relieves the strain of volume variations and maintains the integrity of the SEI under Li stripping/plating cycles. The resulting Li|LiFePO4 cell with TEOS/TEOT electrolyte additives exhibits ultra‐stable cycling performance over 3000 cycles with an extremely low capacity decay rate of 0.008% per cycle. This study of the TEOS/TEOT as synergetic electrolyte additives offers a new method for regulating the interfacial properties of Li anodes.
Engineering Tissues of the Central Nervous System: Interfacing Conductive Biomaterials with Neural Stem/Progenitor Cells
Authors: Bierman‐Duquette Rebecca D. , Safarians Gevick , Huang Joyce , Rajput Bushra , Chen Jessica Y. , Wang Ze Zhong , Seidlits Stephanie K.
Published: November 2021

Conductive biomaterials provide an important control for engineering neural tissues, where electrical stimulation can potentially direct neural stem/progenitor cell (NS/PC) maturation into functional neuronal networks. It is anticipated that stem cell‐based therapies to repair damaged central nervous system (CNS) tissues and ex vivo, “tissue chip” models of the CNS and its pathologies will each benefit from the development of biocompatible, biodegradable, and conductive biomaterials. Here, technological advances in conductive biomaterials are reviewed over the past two decades that may facilitate the development of engineered tissues with integrated physiological and electrical functionalities. First, one briefly introduces NS/PCs of the CNS. Then, the significance of incorporating microenvironmental cues, to which NS/PCs are naturally programmed to respond, into biomaterial scaffolds is discussed with a focus on electrical cues. Next, practical design considerations for conductive biomaterials are discussed followed by a review of studies evaluating how conductive biomaterials can be engineered to control NS/PC behavior by mimicking specific functionalities in the CNS microenvironment. Finally, steps researchers can take to move NS/PC‐interfacing, conductive materials closer to clinical translation are discussed.
Recent Advances in Electrolytes for “Beyond Aqueous” Zinc‐Ion Batteries
Authors: Lv Yanqun , Xiao Ying , Ma Longtao , Zhi Chunyi , Chen Shimou
Published: November 2021

With the growing demands for large‐scale energy storage, Zn‐ion batteries (ZIBs) with distinct advantages, including resource abundance, low‐cost, high‐safety, and acceptable energy density, are considered as potential substitutes for Li‐ion batteries. Although numerous efforts are devoted to design and develop high performance cathodes and aqueous electrolytes for ZIBs, many challenges, such as hydrogen evolution reaction, water evaporation, and liquid leakage, have greatly hindered the development of aqueous ZIBs. Developing “beyond aqueous” electrolytes can be able to avoid these issues due to the absence of water, which are beneficial for the achieving of highly efficient ZIBs. In this review, the recent development of the “beyond aqueous” electrolytes, including conventional organic electrolytes, ionic liquid, all‐solid‐state, quasi‐solid‐state electrolytes, and deep eutectic electrolytes are presented. The critical issues and the corresponding strategies of the designing of “beyond aqueous” electrolytes for ZIBs are also summarized.
Solvent‐Assisted 4D Programming and Reprogramming of Liquid Crystalline Organogels
Authors: Jin Binjie , Liu Jiaqi , Shi Yunpeng , Chen Guancong , Zhao Qian , Yang Shu
Published: November 2021

Encoding molecular ordering during liquid crystalline network (LCN) formation endows preprogrammed but fixed shape morphing in response to external stimuli. The incorporation of dynamic covalent bonds enables shape reprogramming but also permanently alters the network structures. Here, an entropic approach that can program complex shapes via directed solvent evaporation from an isotropic LCN organogel is discoursed. Different shapes can be erased and reprogrammed from the same LCN on demand depending on the modes of deformation of the organogel during solvent evaporation. The ability to decouple network synthesis and molecular alignment relaxes the requirements to LCN chemistry and alignment methods, allowing for the realization of a variety of origami/kirigami structures and 4D shape morphing of LCNs printed from the digital light processing technique with unattainable spatial and temporal controls.
Amphiphilic Bottlebrush Polymeric Binders for High‐Mass‐Loading Cathodes in Lithium‐Ion Batteries
Authors: Kim Nag‐Young , Moon Junsoo , Ryou Myeong‐Hwa , Kim Seung‐Hyeok , Kim Jung‐Hui , Kim Ju‐Myung , Bang Joona , Lee Sang‐Young
Published: November 2021

In contrast to noteworthy advancements in cathode active materials for lithium‐ion batteries, the development of cathode binders has been relatively slow. This issue is more serious for high‐mass‐loading cathodes, which are preferentially used as a facile approach to enable high‐energy‐density Li‐ion batteries. Here, amphiphilic bottlebrush polymers (BBPs) are designed as a new class of cathode binder material. Using poly (acrylic acid) (PAA) as a sidechain, BBPs are synthesized through ring‐opening metathesis polymerization. The BBPs are amphiphilic in nature owing to the hydrophilic PAA sidechains and hydrophobic polynorbornene (PNB) backbones. The PNB backbone allows process compatibility with nonaqueous solvent‐based commercial cathode fabrication, while the PAA sidechain provides strong adhesion between cathode active layers and metallic current collectors. Moreover, the PAA sidechain simultaneously chelates transition metal ions dissolved from cathode active materials (LiNi0.8Mn0.1Co0.1O2 (NCM811)) particles which are chosen as a model material. Driven by the well‐balanced amphiphilicity and bottlebrush‐based structural uniqueness of the BBP binder, the resulting NCM811 cathode exhibits uniform electron/ion conduction networks and dimensional stability. Notably, a high‐mass‐loading (27 mg cm−2, corresponding to 5.2 mAh cm−2) NCM811 cathode with stable cyclability is achieved with an extremely low content (1 wt%) of the BBP binder.
Excellent HER and OER Catalyzing Performance of Se‐Vacancies in Defects‐Engineered PtSe2: From Simulation to Experiment
Authors: Chang Yuan , Zhai Panlong , Hou Jungang , Zhao Jijun , Gao Junfeng
Published: November 2021

Faced with grave climate change and enormous energy demands, effective catalysts have become more and more important due to their significant effects on reducing fossil fuels consumption. The hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) by water splitting are feasible ways to produce clean sustainable energy. Here, atomic structures and related scanning tunneling microscope images of Se defects in PtSe2 are systematically explored. The equilibrium fractions of vacancies under variable conditions are predicted in detail. In addition, it is found that the vacancies are highly kinetically stable, without recovering or aggregation. The Se vacancies in PtSe2 can dramatically enhance the HER performance, comparing to Pt(111). It is also revealed that a PtSe2 monolayer with Se vacancies is also a good OER catalyst. The excellent bipolar catalysis of Se vacancies is further confirmed by experimental measurements. A defective PtSe2 made via direct selenization of Pt foil at 773 K using a chemical vapor deposition process is produced. It is shown that the HER and OER performance of defective PtSe2 is much more efficient than Pt foils by a series of measurements. This work, with its compelling theoretical and experimental studies indicates PtSe2 with Se defects is an ideal bipolar candidate for HER and OER.
Variant connective tissue (joint hypermobility) and dysautonomia are associated with multimorbidity at the intersection between physical and psychological health
Authors: Csecs Jenny L. L. , Dowell Nicholas G. , Savage Georgia K. , Iodice Valeria , Mathias Christopher J. , Critchley Hugo D. , Eccles Jessica A.
Published: November 2021

The symptoms of joint hypermobility extend beyond articular pain. Hypermobile people commonly experience autonomic symptoms (dysautonomia), and anxiety or related psychological issues. We tested whether dysautonomia might mediate the association between hypermobility and anxiety in adults diagnosed with mental health disorders and/or neurodevelopmental conditions (hereon referred to as patients), by quantifying joint hypermobility and symptoms of autonomic dysfunction. Prevalence of generalized joint laxity (hypermobility) in 377 individuals with diagnoses of mental health disorders and/or neurodevelopmental conditions was compared to prevalence recorded in the general population. Autonomic symptom burden was compared between hypermobile and non‐hypermobile patients. Mediation analysis explored relationships between hypermobility, autonomic dysfunction, and anxiety. Patient participants had elevated prevalence of generalized joint laxity (38%) compared to the general population rate of 19% (odds ratio: 2.54 [95% confidence interval: 2.05, 3.16]). Hypermobile participants reported significantly more autonomic symptoms. Symptoms of orthostatic intolerance mediated the relationship between hypermobility and diagnosis of an anxiety disorder. Patients with mental health disorders and/or neurodevelopmental conditions have high rates of joint hypermobility. Accompanying autonomic dysfunction mediates the association between joint hypermobility and clinical anxiety status. Increased recognition of this association can enhance mechanistic understanding and improve the management of multimorbidity expressed in physical symptoms and mental health difficulties.
Multi‐Stimuli‐Induced Mechanical Bending and Reversible Fluorescence Switching in a Single Organic Crystal
Authors: Zheng Xin , Liu Xiaojing , Liu Lijie , Li Xiaochuan , Jiang Song , Niu Caoyuan , Xie Puhui , Liu Guoxing , Cao Zhanqi , Ren Yunlai , Qin Yuchen , Wang Jianji
Published: November 2021

Fluorescent single crystals that respond to multiple external stimuli are of great interest in molecular machines, sensors, and displays. The integration of photo‐ or acid‐induced fluorescence enhancement and bending in one organic crystal, however, has not been reported yet. Herein, we report the interesting plastic photomechanical bending and switching on of the fluorescence of an azine crystal in a single‐crystal transformation, due to extended π‐conjugation and molecular slippage. Moreover, the fluorescent plastic bending driven by multiple volatile acid vapors was firstly observed, and attributed to the synergistic effect of push–pull electronic structure and hydrogen bonding. The single crystal also shows high elasticity under external force. In addition, reversible fluorescence switching can be triggered by grinding and solvent fuming, as well as by the adsorption and desorption of HCl vapor. The integration of plastic, elastic bending and switch‐on fluorescence into one single crystal provides a new strategy for next‐generation smart materials.
Imparting CO2 Electroreduction Auxiliary for Integrated Morphology Tuning and Performance Boosting in a Porphyrin‐based Covalent Organic Framework
Authors: Wang Yi‐Rong , Ding Hui‐Min , Ma Xiao‐Yu , Liu Ming , Yang Yi‐Lu , Chen Yifa , Li Shun‐Li , Lan Ya‐Qian
Published: November 2021

Strategies that enable simultaneous morphology‐tuning and electroreduction performance boosting are much desired for the exploration of covalent organic frameworks in efficient CO2 electroreduction. Herein, a kind of functionalizing exfoliation agent has been selected to simultaneously modify and exfoliate bulk COFs into functional nanosheets and investigate their CO2 electroreduction performance. The obtained nanosheets (Cu−Tph−COF−Dct) with large‐scale (≈1.0 μm) and ultrathin (≈3.8 nm) morphology enable a superior FECH4 (≈80 %) (almost doubly enhanced than bare COF) with large current‐density (−220.0 mA cm−2) at −0.9 V. The boosted performance can be ascribed to the immobilized functionalizing exfoliation agent (Dct groups) with integrated amino and triazine groups that strengthen CO2 absorption/activation, stabilize intermediates and enrich the CO concentration around the Cu active sites as revealed by DFT calculations. The point‐to‐point functionalization strategy for modularly assembling Dct‐functionalized COF catalyst for CO2 electroreduction will open up the attractive possibility of developing COFs as efficient CO2RR electrocatalysts.
Preparing Two‐Dimensional Ordered Li0.33La0.557TiO3 Crystal in Interlayer Channel of Thin Laminar Inorganic Solid‐State Electrolyte towards Ultrafast Li+ Transfer
Authors: Lv Ruixin , Kou Weijie , Guo Shiyuan , Wu Wenjia , Zhang Yatao , Wang Yong , Wang Jingtao
Published: November 2021

Inorganic superionic conductor holds great promise for high‐performance all‐solid‐state lithium batteries. However, the ionic conductivity of traditional inorganic solid electrolytes (ISEs) is always unsatisfactory owing to the grain boundary resistance and large thickness. Here, a 13 μm‐thick laminar framework with ≈1.3 nm interlayer channels is fabricated by self‐assembling rigid, hydrophilic vermiculite (Vr) nanosheets. Then, Li0.33La0.557TiO3 (LLTO) precursors are impregnated in interlayer channels and afterwards in situ sintered to large‐size, oriented, and defect‐free LLTO crystal. We demonstrate that the confinement effect permits ordered arrangement of LLTO crystal along the c‐axis (the fastest Li+ transfer direction), permitting the resultant 15 μm‐thick Vr‐LLTO electrolyte an ionic conductivity of 8.22×10−5 S cm−1 and conductance of 87.2 mS at 30 °C. These values are several times’ higher than that of traditional LLTO‐based electrolytes. Moreover, Vr‐LLTO electrolyte has a compressive modulus of 1.24 GPa. Excellent cycling performance is demonstrated with all‐solid‐state Li/LiFePO4 battery.
Effect of heteroatom‐doped carbon quantum dots on the red emission of metal‐conjugated phthalocyanines through hybridization
Authors: Eryiğit Şule , Gelir Ali , Budak Esranur , Ünlü Caner , Gömleksiz Azize , Özçeşmeci İbrahim , Gül Ahmet
Published: November 2021

Quantum dots (QDs) are significant fluorescent materials for energy transfer studies with phthalocyanines (Pcs) and phthalocyanine (Pc)‐like biomolecules (such as chlorophylls). Carbon‐based QDs, especially, have been used in numerous studies concerning energy transfer with chlorophylls, but the numbers of studies concerning energy transfer between phthalocyanines and carbon‐based QDs are limited. In this study, peripherally, hydroxythioethyl terminal group substituted metal‐free phthalocyanine (H2Pc) and zinc phthalocyanine (ZnPc) were noncovalently (electrostatic and/or π–π interaction) attached to carbon QDs containing boron and nitrogen to form QD‐Pc nanoconjugates. The QD‐Pc conjugates were characterized using different spectroscopic techniques (Fourier transform infrared spectroscopy and transmission electron microscopy). The absorption and fluorescence properties of QD‐Pc structures in solution were studied. It was found that the quantum yields of the QDs slightly decreased from 30% to 25% upon doping the QDs with heteroatoms B and N. Förster resonance energy transfer efficiency was calculated as 33% for BCN‐QD/ZnPc. For the other conjugates, almost no energy transfer from QDs to Pc cores was observed. It was shown that the energy transfer between QDs to Pc cores was completely different from the energy transfer between QDs and photosynthetic pigments, and therefore we concluded that heteroatom doping in the QD structure and the existence of zinc metal in the phthalocyanine structure is obligatory for an efficient energy transfer.
A novel spectrofluorimetric method for determination of lomefloxacin adopting on zinc(II) chelation strategy: Application in human plasma
Authors: Attia Tamer Z. , Omar Mahmoud A. , Nour El‐Deen Deena A. M. , Mohamed Abbas Asmaa , Mohamed Abobakr A.
Published: November 2021

A new sensitive and instantaneous spectrofluorimetric method for efficient determination of lomefloxacin (LMX) in its pure, dosage form and human plasma was designed. The developed method depends on formation of a metal‐chelation compound of LMX as a ligand with zinc(II) in a buffer of acetate (pH 5.5). The following parameters; type of metal, concentration of metal, pH, type of buffer and diluting solvent were optimized. After carefully investigation; 0.2 mM zinc, 2.0 ml acetate buffer (pH 5.5) and water as diluting solvent were set as optimum reaction conditions. Under these conditions, a large increase in the intensity of the fluorescence of LMX was attained at 450 after excitation at 284 nm. The limits of detection and quantification were 5.8 and 1.9 ng ml−1, respectively, with linearity range of 10.0 to 500.0 ng ml−1. The binding mode of LMX and zinc(II) ion (Zn2+) was found to be 2:1, respectively, and confirmed by Job's plot method. Furthermore, it extended to the analysis of LMX in the spiked plasma of humans with percentage recovery (98.70 ± 0.97 to 100.30 ± 1.69%,n = 3).
Determination of organophosphate flame retardant tris(2‐chloroethyl)phosphine based on the luminol–H2O2 chemiluminescence system
Authors: Zhu Huanhuan , Xie Yonghong , Zou Xue , Wang Tengfei , Gong Zhengjun
Published: November 2021

Organophosphorus flame retardants (OPFRs) are new types of environmental pollutants, therefore the rapid and sensitive detection of OPFRs is a very important objective. A new experimental phenomenon was found in which tris(2‐chloroethyl)phosphine (TCEP), a type of OPFR, could effectively enhance the signal of the luminol–H2O2 chemiluminescence (CL) system. Combined with the controllability of flow injection analysis, a rapid, stable, and sensitive CL method was established. The CL intensity responded linearly to the concentration of TCEP in the range 0.5–100 μg/L (R2 = 0.999) with a low detection limit of 33 ng/L. Relative standard deviation (RSD) was 2.2% (n = 7, c = 100 μg/L). Water samples were labelled and recycled with RSDs of 1.1–5.7% and recoveries of 88.7–116.1%. Based on these results, this study established a new CL detection method for the environmental pollutant TCEP.
Emotional processing of sadness and disgust evoked by disaster scenes
Authors: Wang Xin , Jin Jingna , Liu Wenbo , Liu Zhipeng , Yin Tao
Published: November 2021

Objective

Disaster scenes produce long‐term negative feelings in those who experience them. Previous studies have focused on mitigating disaster impacts through directed forgetting or conscious suppression. However, the initial emotional processing of disaster scenes is not fully understood, hindering the comprehension of long‐term disaster impacts. This study aims to investigate how pictures of disaster scenes evoking disgust and sadness are processed via cortical electrical activity.

Methods

Pictures of grief and mutilation from disasters were used to evoke sadness and disgust, respectively. Event‐related desynchronization (ERD) and event‐related potentials (ERPs) were used to quantify the intensity and time‐course of emotional processing.

Results

The information processing of emotional pictures was stronger than neutral pictures, represented by greater declines of alpha ERD. In the posterior ERP components of N1 and EPN, amplitudes for emotional pictures were larger than those for neutral pictures, which reflected the effects of arousal on visual perception. In the anterior ERP components of P2, P3, and LPP, disgust pictures showed higher attention attraction and enhanced encoding memory processing.

Conclusions

Disgust disaster scenarios induced long‐term prominent LPP, which may correspond with the long‐term negative impacts of the disaster.
Using Parental Attachment in Family Court Proceedings: DMM Theory about the Adult Attachment Interview
Authors: Crittenden Patricia M. , Landini Andrea , Spieker Susan J. , Grey Ben
Published: November 2021

Parental attachment refers to the protective and comforting role of parents toward their children. This role has been violated in cases of maltreatment. Understanding the attachment of parents who endanger their children can illuminate the psychological processes behind the harmful behaviour of parents. This paper proposes assessing parental attachment with the Adult Attachment Interview (AAI), classified according to the Dynamic‐Maturational Model of Attachment and Adaptation (DMM). We discuss meta‐analyses of the ‘gold standard' Berkeley method for extracting AAI information. AAIs of maltreating adults classified with the Berkeley method have an improbably high rate of secure attachment, making it inadequate for family forensic applications. In contrast, the DMM uses a theory‐based, developmental expansion of Ainsworth's infant categories to describe a wide array of dimensionally related protective strategies for coping with danger across the lifespan. DMM‐AAIs, classified by trained, reliable professionals and integrated with data from other sources to create an individualised family formulation, meet evidentiary requirements. We call for a programme of research of court‐involved families comparing DMM‐AAI formulations to outcomes of usual methods for determining family services.

‘This paper proposes assessing parental attachment with the Adult Attachment Interview, classified according to the Dynamic‐Maturational Model of Attachment and Adaptation (DMM)’

Key Practitioner Messages

Childhood exposure to danger is crucial to understanding maltreating parents' behaviour.

Adult Attachment Interviews, classified with the DMM method by authorised experts, can reveal motivating psychological processes that are not apparent in parental behaviour.

Information about parents' attachment, together with other information, can help child protection personnel gauge the risk that parents pose to their children and organise personalised treatment plans to reduce that risk.

ABCD Berkeley AAI classifications are not suitable for forensic use.
Sudden bilateral hearing loss after vestibular‐evoked myogenic potentials
Authors: Asakura Shinnosuke , Kamogashira Teru
Published: November 2021

This case report presents bilateral hearing loss after vestibular‐evoked myogenic potential (VEMP) testing. The loud acoustic stimulus used in VEMP testing can cause noise‐induced hearing loss in some cases with high sensitivity to noise exposure or by exceeding individual cochlear safety thresholds.
Subacute thyroiditis after SARS‐CoV‐2 infection
Authors: Semikov Vasiliy I. , Aghayan Davit L. , Shulutko Alexander M. , Khorobrykh Tatyana V. , Aleksandrov Yuriy K. , Mansurova Gaukhar T. , Kazaryan Airazat M.
Published: November 2021

Viral infections are considered as etiologic factors of subacute thyroiditis. The true incidence of subacute thyroiditis, caused by SARS‐CoV‐2 infection, is probably considerable since it is often masked by more dramatic affection of the respiratory system. This report presents two female patients who developed de Quervain's thyroiditis after COVID‐19 disease.
Rehabilitation of a deep bite patient with worn dentition using minimally invasive approach: A 3‐year follow‐up
Authors: Hasanzade Mahya , Ghodsi Safoura , Yaghoobi Negin
Published: November 2021

Full mouth rehabilitation of severely worn teeth represents a challenging situation for dental clinicians. This case report describes the minimally invasive interdisciplinary approach for treatment of severely worn dentition with a loss of vertical dimension of occlusion. After 3 years of follow‐up, no complication was observed.
Coordination‐Induced Band Gap Reduction in a Metal–Organic Framework
Authors: Peeples Craig A. , Çetinkaya Ahmet , Tholen Patrik , Schmitt Franz‐Josef , Zorlu Yunus , Bin Yu Kai , Yazaydin Ozgur , Beckmann Jens , Hanna Gabriel , Yücesan Gündoğ
Published: November 2021

Herein, we report on the synthesis of a microporous, three‐dimensional phosphonate metal–organic framework (MOF) with the composition Cu3(H5‐MTPPA)2 ⋅ 2 NMP (H8‐MTPPA=methane tetra‐p‐phenylphosphonic acid and NMP=N‐methyl‐2‐pyrrolidone). This MOF, termed TUB1, has a unique one‐dimensional inorganic building unit composed of square planar and distorted trigonal bipyramidal copper atoms. It possesses a (calculated) BET surface area of 766.2 m2/g after removal of the solvents from the voids. The Tauc plot for TUB1 yields indirect and direct band gaps of 2.4 eV and 2.7 eV, respectively. DFT calculations reveal the existence of two spin‐dependent gaps of 2.60 eV and 0.48 eV for the alpha and beta spins, respectively, with the lowest unoccupied crystal orbital for both gaps predominantly residing on the square planar copper atoms. The projected density of states suggests that the presence of the square planar copper atoms reduces the overall band gap of TUB1, as the beta‐gap for the trigonal bipyramidal copper atoms is 3.72 eV.
Angucycline and angucyclinone derivatives from the marine‐derived Streptomyces sp.
Authors: Liu Ming , Yang Ying‐Jie , Gong Ge , Li Zhi , Zhang Lu , Guo Lin , Xu Bo , Zhang Shu‐Min , Xie Ze‐Ping
Published: November 2021

Atramycin C (1), one new angucycline bearing an O‐6 rhamnose side chain, along with one new highly hydroxylated angucyclinone emycin G (2), and ten known analogs (3–12) were isolated from the marine‐derived Streptomyces sp. strain BHB‐032. Their structures were assigned by spectroscopic analysis and comparison with literature data. The absolute configuration of the sugar unit of 1 was assigned as 6‐O‐α‐l‐rhamnoside, based on the analysis of the coupling constants and chemical derivatization, whereas the absolute configuration of 2 was determined by X‐ray diffraction. Furthermore, the stereochemistry of saccharothrixin A (3) and SNA‐8073‐A (4) was established unequivocally by X‐ray crystallography for the first time. Compounds 1 and 2 exhibited moderate antimicrobial activities with minimum inhibitory concentration (MIC) values ranging from 16 to 64 μg/ml.
Impact of cyclofructan derivatives as efficient chiral selector in chiral analysis: An overview
Authors: Aboul‐Enein Hassan Y. , Kannappan Valliappan , Kanthiah Selvakumar
Published: November 2021

The development of chiral selectors for the separation and analysis of chiral molecules has been an evolving process happening over three decades, since the introduction of the first chiral stationary phase (CSP) in 1938. The main impetus for designing new chiral selectors is to get to most promising one which has a broad chiral recognition property, separation capability for a wide range of chiral analytes, and the cost‐effective CSP, which is also a major concern. Today, we have more than 100 commercially available CSPs, and these are prepared by coating or immobilizing the classical chiral selectors on to the chromatographic support, normally, silica gel. The purpose of this review is to look at progress and the impact of cyclofructan derivatives, a novel chiral selector introduced recently, for performing chiral analysis.
On stress in abdominal aortic aneurysm: Linear versus non‐linear analysis and aneurysm rupture risk
Authors: Wittek Adam , Alkhatib Farah , Vitásek Radek , Polzer Stanislav , Miller Karol
Published: November 2021

We present comprehensive biomechanical analyses of abdominal aortic aneurysms (AAA) for 43 patients. We compare stress magnitudes and stress distributions within arterial walls of abdominal aortic aneurysms (AAA) obtained using two simulation and modelling methods: (a) Fully automated and computationally very efficient linear method embedded in the software platform Biomechanics based Prediction of Aneurysm Rupture Risk (BioPARR), freely available from https://bioparr.mech.uwa.edu.au/; (b) More complex and much more computationally demanding Non‐Linear Iterative Stress Analysis (Non‐LISA) that uses a non‐linear inverse iterative approach and strongly non‐linear material model. Both methods predicted localised high stress zones with over 90% of AAA model volume fraction subjected to stress below 20% of the 99th percentile maximum principal stress. However, for the non‐linear iterative method, the peak maximum principal stress (and 99th percentile maximum principal stress) was higher and the stress magnitude in the low stress area lower than for the automated linear method embedded in BioPARR. Differences between the stress distributions obtained using the two methods tended to be particularly pronounced in the areas where the AAA curvature was large. Performance of the selected characteristic features of the stress fields (we used 99th percentile maximum principal stress) obtained using BioPARR and Non‐LISA in distinguishing between the AAAs that would rupture and remain intact was for practical purposes the same for both methods.
UAV‐derived imagery for vegetation structure estimation in rangelands: validation and application
Authors: Zhang Junzhe , Okin Gregory S. , Zhou Bo , Karl Jason W.
Published: November 2021

The purpose of this study is to develop an unmanned aerial vehicle (UAV)‐based remote sensing method that can estimate vegetation indicators in arid and semiarid rangelands. This method was used to quantify six rangeland indicators (canopy size, bare soil gap size, plant height, scaled height, vegetation cover, and bare soil cover) in a semiarid grass–shrub ecosystem. The drone‐based estimates were validated with field measurements by using the standard transect methods (gap intercept, drop disk, and line‐point intercept methods) in the spring and summer of 2017. The drone‐based estimates showed strong agreements with in situ measurements in cases where deciduous vegetation (mesquite) had leaves with R2 for bare soil gap size and vegetation height of 0.97 and 0.89 in the summer, respectively. The RMSE of bare soil gap size and vegetation height are 0.2 m and 6.72 cm in the summer, respectively. Based on these results, we found that drone‐based remote sensing proved to be an efficient and highly accurate method that serves as a complement to field measurements for rangeland indicator estimation. We discussed the possible applications of drone‐based products on arid and semiarid rangelands: the spatially explicit input of an ecological model, to detect and characterize non‐stationarity, and to detect landscape anisotropy.