bluuebunny/crossref_metadata_2025 huggingface dataset:
Do You See What I See? Insights from Using Google Glass for Disaster Telemedicine Triage
Authors: Cicero Mark X. , Walsh Barbara , Solad Yauheni , Whitfill Travis , Paesano Geno , Kim Kristin , Baum Carl R. , Cone David C.
Published: January 2015

Introduction

Disasters are high-stakes, low-frequency events. Telemedicine may offer a useful adjunct for paramedics performing disaster triage. The objective of this study was to determine the feasibility of telemedicine in disaster triage, and to determine whether telemedicine has an effect on the accuracy of triage or the time needed to perform triage.

Methods

This is a feasibility study in which an intervention team of two paramedics used the mobile device Google Glass (Google Inc; Mountain View, California USA) to communicate with an off-site physician disaster expert. The paramedic team triaged simulated disaster victims at the triennial drill of a commercial airport. The simulated victims had preassigned expected triage levels. The physician had an audio-video interface with the paramedic team and was able to observe the victims remotely. A control team of two paramedics performed disaster triage in the usual fashion. Both teams used the SMART Triage System (TSG Associates LLP; Halifax, England), which assigns patients into Red, Yellow, Green, and Black triage categories. The paramedics were video recorded, and their time required to triage was logged. It was determined whether the intervention team and the control team varied regarding accuracy of triage. Finally, the amount of time the intervention team needed to triage patients when telemedicine was used was compared to when that team did not use telemedicine.

Results

The two teams triaged the same 20 patients. There was no significant difference between the two groups in overall triage accuracy (85.7% for the intervention group vs 75.9% for the control group;P= .39). Two patients were triaged with telemedicine. For the intervention group, there was a significant difference in time to triage patients with telemedicine versus those without telemedicine (35.5 seconds; 95% CI, 72.5-143.5 vs 18.5 seconds; 95% CI, 13.4-23.6;P= .041).

Conclusion

There was no increase in triage accuracy when paramedics evaluating disaster victims used telemedicine, and telemedicine required more time than conventional triage. There are a number of obstacles to available technology that, if overcome, might improve the utility of telemedicine in disaster response.

CiceroMX,WalshB,SoladY,WhitfillT,PaesanoG,KimK,BaumCR,ConeDC.Do you see what I see? Insights from using Google Glass for disaster telemedicine triage.Prehosp Disaster Med.2015;30(1):1-5.
Peer mentoring for radiotherapy planning skills development: a pilot study
Authors: Bridge P. , Ellemor N. J. , Carmichael M. , Gibson G.
Published: January 2015

Introduction

This study aimed to determine the potential role and guidelines for implementation of skill-based peer mentoring for radiotherapy planning education.

Methods

After four weekly mentoring sessions, both Year 3 mentors (n=9) and Year 2 mentees (n=9) were invited to complete a short online questionnaire relating to the impact of the initiative. The tool contained a mixture of Likert-style questions concerning student enjoyment and perceived usefulness of the initiative as well as more qualitative open questions that gathered perceptions of the peer mentoring process, implementation methods and potential future scope.

Results

Several key discussion themes related to benefits to each stakeholder group, challenges arising, improvements and potential future directions. There were high levels of enjoyment and perceived value of the mentoring from both sides with 100% of the 18 respondents enjoying the experience. The informal format encouraged further learning, while mentors reported acquisition of valuable skills and gains in knowledge.

Conclusions

Peer mentoring has a valuable and enjoyable role to play in radiotherapy planning training and helps consolidate theoretical understanding for experienced students. An informal approach allows for students to adopt the most appropriate mentoring model for their needs while providing them with a free space to engender additional discussion.
Spanish Version of the Pain Vigilance and Awareness Questionnaire: Psychometric Properties in a Sample of Women with Fibromyalgia
Authors: Pilar Martínez M. , Miró Elena , Sánchez Ana I. , Lami María J. , Prados Germán , Ávila Daniela
Published: January 2015

Excessive attention to pain is a common psychological characteristic among people who suffer from chronic pain. The Pain Vigilance and Awareness Questionnaire (PVAQ) is an internationally accepted tool to assess this feature, although there is no validated version of this measure for Spanish people with fibromyalgia. Since this pain syndrome mainly affects women, the aim of this study was to determine the psychometric properties of the PVAQ in Spanish women with fibromyalgia. A group of 242 women diagnosed with fibromyalgia aged between 20 and 66 years participated in the study. The goodness of fit of several structures of the PVAQ reported in previous studies was compared via confirmatory factor analysis. A two-factor solution (active vigilance and passive awareness) of the 9-item shortened version (PVAQ-9) was identified as the most appropriate (RMSEA = .08, NNFI = .96, CFI = .97, GFI = .87). It showed good reliability (internal consistency α = .82), convergent validity and divergent validity (p < .01). The optimal cutoff point for identifying fibromyalgia women with worse daily functioning was a score of 24.5, with a sensitivity of .71 and a specificity of .75. The relevance of vigilance to pain for clinical research in fibromyalgia is discussed.
Adaptive Förderung zur Vorbereitung auf den Übergang vom Elementar- in den Primarbereich am Beispiel des Bereichs Mathematik
Authors: Bruns Julia , Eichen Lars
Published: January 2015

Die vorliegende quasi-experimentelle Querschnittsuntersuchung verfolgt das Ziel, adaptive Förderleistungen elementarpädagogischer Fachpersonen zu erfassen und Zusammenhänge mit anderen Komponenten elementarpädagogischer Arbeit aufzudecken. Im Zentrum steht die Frage: Welcher Zusammenhang zeigt sich zwischen der Beobachtungsintensität, den diagnostischen Fähigkeiten und der Qualität der adaptiven Förderpraxis im Elementarbereich? Fokussiert wird die adaptive Förderleistung einer Teilstichprobe mit n = 31 Fachpersonen in Bezug auf die Teilstichprobe von n = 62 Kinder. Dazu werden verschiedene Methoden auf Kinder- und Fachpersonenebene im Sinne eines mixed-methods Designs miteinander verknüpft (Mathematiktest ‚zahlenstark‘, standardisierte Beobachtung, standardisiertes Interview). Die Ergebnisse zeigen, dass keiner Fachperson eine optimale Förderung zweier Kinder gelingt. Im Hinblick auf den Übergang zwischen Elementar- und Primarbereich kann gefolgert werden, dass die Kinder unzureichend in ihren individuellen Bildungsprozessen begleitet werden.
Divergence across diet, time and populations rules out parallel evolution in the gut microbiomes of Trinidadian guppies
Authors: Sullam Karen E , Rubin Benjamin E R , Dalton Christopher M , Kilham Susan S , Flecker Alexander S , Russell Jacob A
Published: January 2015

Diverse microbial consortia profoundly influence animal biology, necessitating an understanding of microbiome variation in studies of animal adaptation. Yet, little is known about such variability among fish, in spite of their importance in aquatic ecosystems. The Trinidadian guppy, Poecilia reticulata, is an intriguing candidate to test microbiome-related hypotheses on the drivers and consequences of animal adaptation, given the recent parallel origins of a similar ecotype across streams. To assess the relationships between the microbiome and host adaptation, we used 16S rRNA amplicon sequencing to characterize gut bacteria of two guppy ecotypes with known divergence in diet, life history, physiology and morphology collected from low-predation (LP) and high-predation (HP) habitats in four Trinidadian streams. Guts were populated by several recurring, core bacteria that are related to other fish associates and rarely detected in the environment. Although gut communities of lab-reared guppies differed from those in the wild, microbiome divergence between ecotypes from the same stream was evident under identical rearing conditions, suggesting host genetic divergence can affect associations with gut bacteria. In the field, gut communities varied over time, across streams and between ecotypes in a stream-specific manner. This latter finding, along with PICRUSt predictions of metagenome function, argues against strong parallelism of the gut microbiome in association with LP ecotype evolution. Thus, bacteria cannot be invoked in facilitating the heightened reliance of LP guppies on lower-quality diets. We argue that the macroevolutionary microbiome convergence seen across animals with similar diets may be a signature of secondary microbial shifts arising some time after host-driven adaptation.
Energy landscapes shape microbial communities in hydrothermal systems on the Arctic Mid-Ocean Ridge
Authors: Dahle Håkon , Økland Ingeborg , Thorseth Ingunn H , Pederesen Rolf B , Steen Ida H
Published: January 2015

Methods developed in geochemical modelling combined with recent advances in molecular microbial ecology provide new opportunities to explore how microbial communities are shaped by their chemical surroundings. Here, we present a framework for analyses of how chemical energy availability shape chemotrophic microbial communities in hydrothermal systems through an investigation of two geochemically different basalt-hosted hydrothermal systems on the Arctic Mid-Ocean Ridge: the Soria Moria Vent field (SMVF) and the Loki’s Castle Vent Field (LCVF). Chemical energy landscapes were evaluated through modelling of the Gibbs energy from selected redox reactions under different mixing ratios between seawater and hydrothermal fluids. Our models indicate that the sediment-influenced LCVF has a much higher potential for both anaerobic and aerobic methane oxidation, as well as aerobic ammonium and hydrogen oxidation, than the SMVF. The modelled energy landscapes were used to develop microbial community composition models, which were compared with community compositions in environmental samples inside or on the exterior of hydrothermal chimneys, as assessed by pyrosequencing of partial 16S rRNA genes. We show that modelled microbial communities based solely on thermodynamic considerations can have a high predictive power and provide a framework for analyses of the link between energy availability and microbial community composition.
Culture and molecular-based profiles show shifts in bacterial communities of the upper respiratory tract that occur with age
Authors: Stearns Jennifer C , Davidson Carla J , McKeon Suzanne , Whelan Fiona J , Fontes Michelle E , Schryvers Anthony B , Bowdish Dawn M E , Kellner James D , Surette Michael G
Published: January 2015

The upper respiratory tract (URT) is a crucial site for host defense, as it is home to bacterial communities that both modulate host immune defense and serve as a reservoir of potential pathogens. Young children are at high risk of respiratory illness, yet the composition of their URT microbiota is not well understood. Microbial profiling of the respiratory tract has traditionally focused on culturing common respiratory pathogens, whereas recent culture-independent microbiome profiling can only report the relative abundance of bacterial populations. In the current study, we used both molecular profiling of the bacterial 16S rRNA gene and laboratory culture to examine the bacterial diversity from the oropharynx and nasopharynx of 51 healthy children with a median age of 1.1 years (range 1–4.5 years) along with 19 accompanying parents. The resulting profiles suggest that in young children the nasopharyngeal microbiota, much like the gastrointestinal tract microbiome, changes from an immature state, where it is colonized by a few dominant taxa, to a more diverse state as it matures to resemble the adult microbiota. Importantly, this difference in bacterial diversity between adults and children accompanies a change in bacterial load of three orders of magnitude. This indicates that the bacterial communities in the nasopharynx of young children have a fundamentally different structure from those in adults and suggests that maturation of this community occurs sometime during the first few years of life, a period that includes ages at which children are at the highest risk for respiratory disease.
Similarities and seasonal variations in bacterial communities from the blood of rodents and from their flea vectors
Authors: Cohen Carmit , Toh Evelyn , Munro Daniel , Dong Qunfeng , Hawlena Hadas
Published: January 2015

Vector-borne microbes are subject to the ecological constraints of two distinct microenvironments: that in the arthropod vector and that in the blood of its vertebrate host. Because the structure of bacterial communities in these two microenvironments may substantially affect the abundance of vector-borne microbes, it is important to understand the relationship between bacterial communities in both microenvironments and the determinants that shape them. We used pyrosequencing analyses to compare the structure of bacterial communities in Synosternus cleopatrae fleas and in the blood of their Gerbillus andersoni hosts. We also monitored the interindividual and seasonal variability in these bacterial communities by sampling the same individual wild rodents during the spring and again during the summer. We show that the bacterial communities in each sample type (blood, female flea or male flea) had a similar phylotype composition among host individuals, but exhibited seasonal variability that was not directly associated with host characteristics. The structure of bacterial communities in male fleas and in the blood of their rodent hosts was remarkably similar and was dominated by flea-borne Bartonella and Mycoplasma phylotypes. A lower abundance of flea-borne bacteria and the presence of Wolbachia phylotypes distinguished bacterial communities in female fleas from those in male fleas and in rodent blood. These results suggest that the overall abundance of a certain vector-borne microbe is more likely to be determined by the abundance of endosymbiotic bacteria in the vector, abundance of other vector-borne microbes co-occurring in the vector and in the host blood and by seasonal changes, than by host characteristics.
CCR7-dependent trafficking of RORγ+ ILCs creates a unique microenvironment within mucosal draining lymph nodes
Authors: Mackley Emma C. , Houston Stephanie , Marriott Clare L. , Halford Emily E. , Lucas Beth , Cerovic Vuk , Filbey Kara J. , Maizels Rick M. , Hepworth Matthew R. , Sonnenberg Gregory F. , Milling Simon , Withers David R.
Published: January 2015

Presentation of peptide:MHCII by RORγ-expressing group 3 innate lymphoid cells (ILC3s), which are enriched within gut tissue, is required for control of CD4 T-cell responses to commensal bacteria. It is not known whether ILC populations migrate from their mucosal and peripheral sites to local draining secondary lymphoid tissues. Here we demonstrate that ILC3s reside within the interfollicular areas of mucosal draining lymph nodes, forming a distinct microenvironment not observed in peripheral lymph nodes. By photoconverting intestinal cells in Kaede mice we reveal constitutive trafficking of ILCs from the intestine to the draining mesenteric lymph nodes, which specifically for the LTi-like ILC3s was CCR7-dependent. Thus, ILC populations traffic to draining lymph nodes using different mechanisms.
On-chip detection of non-classical light by scalable integration of single-photon detectors
Authors: Najafi Faraz , Mower Jacob , Harris Nicholas C. , Bellei Francesco , Dane Andrew , Lee Catherine , Hu Xiaolong , Kharel Prashanta , Marsili Francesco , Assefa Solomon , Berggren Karl K. , Englund Dirk
Published: January 2015

Photonic-integrated circuits have emerged as a scalable platform for complex quantum systems. A central goal is to integrate single-photon detectors to reduce optical losses, latency and wiring complexity associated with off-chip detectors. Superconducting nanowire single-photon detectors (SNSPDs) are particularly attractive because of high detection efficiency, sub-50-ps jitter and nanosecond-scale reset time. However, while single detectors have been incorporated into individual waveguides, the system detection efficiency of multiple SNSPDs in one photonic circuit—required for scalable quantum photonic circuits—has been limited to <0.2%. Here we introduce a micrometer-scale flip-chip process that enables scalable integration of SNSPDs on a range of photonic circuits. Ten low-jitter detectors are integrated on one circuit with 100% device yield. With an average system detection efficiency beyond 10%, and estimated on-chip detection efficiency of 14–52% for four detectors operated simultaneously, we demonstrate, to the best of our knowledge, the first on-chip photon correlation measurements of non-classical light.
Combining gene mutation with gene expression data improves outcome prediction in myelodysplastic syndromes
Authors: Gerstung Moritz , Pellagatti Andrea , Malcovati Luca , Giagounidis Aristoteles , Porta Matteo G Della , Jädersten Martin , Dolatshad Hamid , Verma Amit , Cross Nicholas C. P. , Vyas Paresh , Killick Sally , Hellström-Lindberg Eva , Cazzola Mario , Papaemmanuil Elli , Campbell Peter J. , Boultwood Jacqueline
Published: January 2015

Cancer is a genetic disease, but two patients rarely have identical genotypes. Similarly, patients differ in their clinicopathological parameters, but how genotypic and phenotypic heterogeneity are interconnected is not well understood. Here we build statistical models to disentangle the effect of 12 recurrently mutated genes and 4 cytogenetic alterations on gene expression, diagnostic clinical variables and outcome in 124 patients with myelodysplastic syndromes. Overall, one or more genetic lesions correlate with expression levels of ~20% of all genes, explaining 20–65% of observed expression variability. Differential expression patterns vary between mutations and reflect the underlying biology, such as aberrant polycomb repression for ASXL1 and EZH2 mutations or perturbed gene dosage for copy-number changes. In predicting survival, genomic, transcriptomic and diagnostic clinical variables all have utility, with the largest contribution from the transcriptome. Similar observations are made on the TCGA acute myeloid leukaemia cohort, confirming the general trends reported here.
Innate sensing of microbial products promotes wound-induced skin cancer
Authors: Hoste Esther , Arwert Esther N. , Lal Rohit , South Andrew P. , Salas-Alanis Julio C. , Murrell Dedee F. , Donati Giacomo , Watt Fiona M.
Published: January 2015

The association between tissue damage, chronic inflammation and cancer is well known. However, the underlying mechanisms are unclear. Here we characterize a mouse model in which constitutive epidermal extracellular-signal-regulated kinase-MAP-kinase signalling results in epidermal inflammation, and skin wounding induces tumours. We show that tumour incidence correlates with wound size and inflammatory infiltrate. Ablation of tumour necrosis factor receptor (TNFR)-1/-2, Myeloid Differentiation primary response gene 88 or Toll-like receptor (TLR)-5, the bacterial flagellin receptor, but not other innate immune sensors, in radiosensitive leukocytes protects against tumour formation. Antibiotic treatment inhibits, whereas injection of flagellin induces, tumours in a TLR-5-dependent manner. TLR-5 is also involved in chemical-induced skin carcinogenesis in wild-type mice. Leukocytic TLR-5 signalling mediates upregulation of the alarmin HMGB1 (High Mobility Group Box 1) in wound-induced papillomas. HMGB1 is elevated in tumours of patients with Recessive Dystrophic Epidermolysis Bullosa, a disease characterized by chronic skin damage. We conclude that in our experimental model the combination of bacteria, chronic inflammation and wounding cooperate to trigger skin cancer.
Tropomodulin3 is a novel Akt2 effector regulating insulin-stimulated GLUT4 exocytosis through cortical actin remodeling
Authors: Lim Chun-Yan , Bi Xuezhi , Wu Donghai , Kim Jae Bum , Gunning Peter W. , Hong Wanjin , Han Weiping
Published: January 2015

Akt2 and its downstream effectors mediate insulin-stimulated GLUT4-storage vesicle (GSV) translocation and fusion with the plasma membrane (PM). Using mass spectrometry, we identify actin-capping protein Tropomodulin 3 (Tmod3) as an Akt2-interacting partner in 3T3-L1 adipocytes. We demonstrate that Tmod3 is phosphorylated at Ser71 on insulin-stimulated Akt2 activation, and Ser71 phosphorylation is required for insulin-stimulated GLUT4 PM insertion and glucose uptake. Phosphorylated Tmod3 regulates insulin-induced actin remodelling, an essential step for GSV fusion with the PM. Furthermore, the interaction of Tmod3 with its cognate tropomyosin partner, Tm5NM1 is necessary for GSV exocytosis and glucose uptake. Together these results establish Tmod3 as a novel Akt2 effector that mediates insulin-induced cortical actin remodelling and subsequent GLUT4 membrane insertion. Our findings suggest that defects in cytoskeletal remodelling may contribute to impaired GLUT4 exocytosis and glucose uptake.
Distinct p21 requirements for regulating normal and self-reactive T cells through IFN-γ production
Authors: Daszkiewicz Lidia , Vázquez-Mateo Cristina , Rackov Gorjana , Ballesteros-Tato André , Weber Kathrin , Madrigal-Avilés Adrián , Di Pilato Mauro , Fotedar Arun , Fotedar Rati , Flores Juana M. , Esteban Mariano , Martínez-A Carlos , Balomenos Dimitrios
Published: January 2015

Self/non-self discrimination characterizes immunity and allows responses against pathogens but not self-antigens. Understanding the principles that govern this process is essential for designing autoimmunity treatments. p21 is thought to attenuate autoreactivity by limiting T cell expansion. Here, we provide direct evidence for a p21 role in controlling autoimmune T cell autoreactivity without affecting normal T cell responses. We studied C57BL/6, C57BL/6/lpr and MRL/lpr mice overexpressing p21 in T cells and showed reduced autoreactivity and lymphadenopathy in C57BL/6/lpr and reduced mortality in MRL/lpr mice. p21 inhibited effector/memory CD4+ CD8+ and CD4−CD8−lpr T cell accumulation without altering defective lpr apoptosis. This was mediated by a previously non-described p21 function in limiting T cell overactivation and overproduction of IFN-γ, a key lupus cytokine. p21 did not affect normal T cell responses, revealing differential p21 requirements for autoreactive and normal T cell activity regulation. The underlying concept of these findings suggests potential treatments for lupus and autoimmune lymphoproliferative syndrome, without compromising normal immunity.
A unique mechanism of successful fertilization in a domestic bird
Authors: Sasanami Tomohiro , Izumi Shunsuke , Sakurai Naoki , Hirata Toshifumi , Mizushima Shusei , Matsuzaki Mei , Hiyama Gen , Yorinaga Eriko , Yoshimura Takashi , Ukena Kazuyoshi , Tsutsui Kazuyoshi
Published: January 2015

Fertilization is an indispensable step for formation of a zygote in sexual reproduction, leading to species survival. When mating occurs, sperm is transported to the female reproductive tracts via the seminal plasma (SP). SP is derived from male accessory sex glands and it plays pivotal roles for fertilization in animals. However, molecular mechanisms of SP or a fluid derived from male accessory sex glands for successful fertilization remain unclear. Here, we report that in male quail the cloacal gland (CG) produces prostaglandin F2α (PGF2α) that contributes to successful fertilization. PGF2α, as well as the secretion of CG (CGS), induced vaginal contractions and caused the opening of the entrance of the sperm storage tubules, the structures responsible for the long-term sperm storage and fertilization. The removal of CGS from the male before mating reduced the fertility, but the supplementation of CGS or PGF2α rescued the subfertility. We further showed that male CG contains glucose that is utilized as energy source for the intrinsic sperm mobility after transportation to female vagina. This mechanism, in concert with the excitatory effects of PGF2α enables successful fertilization in the domestic bird.
Fluorescence imaging of selenol in HepG2 cell apoptosis induced by Na2SeO3
Authors: Kong Fanpeng , Hu Bo , Gao Yan , Xu Kehua , Pan Xiaohong , Huang Fang , Zheng Qiuling , Chen Hao , Tang Bo
Published: January 2015

In order to investigate the Na2SeO3anticancer mechanism in HepG2 cells, a novel selenol fluorescence probe has been designed and used to image selenocysteine (Sec) in living cells andin vivo.
The importance of loop length on the stability of i-motif structures
Authors: Gurung Sarah P. , Schwarz Christine , Hall James P. , Cardin Christine J. , Brazier John A.
Published: January 2015

I-motif stability is enhanced by short loop lengths compared to long loop lengths.
A synthetic biology approach for the transformation of l-α-amino acids to the corresponding enantiopure (R)- or (S)-α-hydroxy acids
Authors: Gourinchas Geoffrey , Busto Eduardo , Killinger Manuela , Richter Nina , Wiltschi Birgit , Kroutil Wolfgang
Published: January 2015

A synthetic biology approach enabled the design of a single E. coli cell catalyst co-expressing three enzymes (l-AAD, l- or d-HIC and FDH) for the quantitatively transformation of l-amino acids to the corresponding optically pure (R)- and (S)-α-hydroxy acids.
Synthesis of polyfunctional secondary amines by the addition of functionalized zinc reagents to nitrosoarenes
Authors: Dhayalan Vasudevan , Sämann Christoph , Knochel Paul
Published: January 2015

Aryl, heteroaryl or adamantyl zinc reagents add in the presence of magnesium-salts and LiCl to various aryl or heteroaryl nitroso arenes producing after reductive work-up polyfunctional secondary amines.
Photochemical synthesis of size-tailored hexagonal ZnS quantum dots
Authors: Gonzalez Carlos M. , Wu Wei-Chen , Tracy Joseph B. , Martin Benjamin
Published: January 2015

Photochemically generated ketyl radicals were employed for the synthesis of hexagonal ZnS quantum dots at room temperature.
A metal-based tumour necrosis factor-alpha converting enzyme inhibitor
Authors: Leung Chung-Hang , Liu Li-Juan , Lu Lihua , He Bingyong , Kwong Daniel W. J. , Wong Chun-Yuen , Ma Dik-Lung
Published: January 2015

We report herein a novel iridium(iii) complex1as an antitumour necrosis factor agent and the first metal-based inhibitor of TACE enzymatic activity.
Asymmetric catalysis activated by visible light
Authors: Meggers Eric
Published: January 2015

Recent advances in merging visible light activated photochemistry with asymmetric catalysis are summarized and discussed.
Stabilizing electrochemical carbon capture membrane with Al2O3 thin-film overcoating synthesized by chemical vapor deposition
Authors: Tong Jingjing , Si Fengzhan , Zhang Lingling , Fang Jie , Han Minfang , Huang Kevin
Published: January 2015

The stability of electrochemical silver-carbonate dual-phase membranes can be significantly enhanced by overcoating the surfaces of porous silver matrix with a uniform layer of Al2O3 thin-film derived from chemical vapor deposition.
Synthesis of spiroindanes by palladium-catalyzed oxidative annulation of non- or weakly activated 1,3-dienes involving C–H functionalization
Authors: Khan Imtiaz , Chidipudi Suresh Reddy , Lam Hon Wai
Published: January 2015

The palladium-catalyzed oxidative annulation of non- or weakly activated 1,3-dienes with 2-aryl cyclic 1,3-dicarbonyl compounds is described.
Salicylic acids as readily available starting materials for the synthesis of meta-substituted biaryls
Authors: Luo Junfei , Preciado Sara , Larrosa Igor
Published: January 2015

Salicylic acids are shown to be readily available and versatile starting materials that easily undergo a tandem arylation–protodecarboxylation process under Pd-catalysis. The corresponding meta-arylphenols can subsequently be easily transformed into a variety of meta-functionalized biaryls, highlighting the versatility of this approach to access this structural motif.
Observation of aliphatic C–H⋯X hydrogen bonds in imidazolium ionic liquids
Authors: Khrizman Alexander , Cheng Hiu Yan , Bottini Gualberto , Moyna Guillermo
Published: January 2015

Measurement of H/D isotope effects on the19F resonances of sequentially deuterated 1-n-butyl-3-methylimidazolium hexafluorophosphate and tetrafluoroborate isotopologues reveals the formation of aliphatic C–H⋯X hydrogen bonds between the fluorinated anions and protons along theN-alkyl sidechains of the cations.
Controlled formation of core–shell structures with uniform AlPO4 nanoshells
Authors: Yang Fen-Li , Zhang Wei , Chi Zi-Xiang , Cheng Fu-Quan , Chen Ji-Tao , Cao An-Min , Wan Li-Jun
Published: January 2015

Uniform AlPO4 nanoshells are successfully achieved on different core materials by controlling their formation kinetics in solution.
Immobilization of polyoxometalates in the Zr-based metal organic framework UiO-67
Authors: Salomon William , Roch-Marchal Catherine , Mialane Pierre , Rouschmeyer Paul , Serre Christian , Haouas Mohamed , Taulelle Francis , Yang Shu , Ruhlmann Laurent , Dolbecq Anne
Published: January 2015

We report the successful synthesis of several POM@UiO-67 composites and their characterization by a panel of complementary techniques.
Hole delocalization over adenine tracts in single stranded DNA oligonucleotides
Authors: Capobianco Amedeo , Caruso Tonino , Peluso Andrea
Published: January 2015

The spin density of oxidized single stranded DNA oligomers is distributed over adenine tracts forming delocalized polarons.
Thermal and shape stability of high-index-faceted rhodium nanoparticles: a molecular dynamics investigation
Authors: Zeng Xiang-Ming , Huang Rao , Wen Yu-Hua , Sun Shi-Gang
Published: January 2015

Atomistic simulations are used to investigate the thermodynamic and shape stability of tetrahexahedral Rh nanaoparticles with high-index facets.
Confinement of massless Dirac fermions in the graphene matrix induced by the B/N heteroatoms
Authors: Yu Shansheng , Zheng Weitao , Ao Zhimin , Li Sean
Published: January 2015

The p-/n-type massless Dirac fermions are confined around an extended 1-D defect in graphene.
An evaporation-induced tri-consistent assembly route towards nitrogen-doped carbon microfibers with ordered mesopores for high performance supercapacitors
Authors: Liu Ruili , Pan Lixia , Wan Li , Wu Dongqing
Published: January 2015

Prepared via an evaporation-induced tri-consistent assembly approach, nitrogen-doped mesoporous carbon microfibers exhibit enhanced capacity, excellent rate capability and durability in electric double-layer capacitors.
Fast oxygen exchange and diffusion kinetics of grain boundaries in Sr-doped LaMnO3thin films
Authors: Navickas Edvinas , Huber Tobias M. , Chen Yan , Hetaba Walid , Holzlechner Gerald , Rupp Ghislain , Stöger-Pollach Michael , Friedbacher Gernot , Hutter Herbert , Yildiz Bilge , Fleig Jürgen
Published: January 2015

Isotope exchange depth profile measurements were performed on columnar/epitaxial LSM thin films with varied microstructure. These uncover the importance of grain boundaries for oxygen reduction reaction and oxide ion diffusion.
Simulations of room temperature ionic liquids: from polarizable to coarse-grained force fields
Authors: Salanne Mathieu
Published: January 2015

This perspective article summarizes the recent advances in the classical molecular modelling of room temperature ionic liquids.
Correction: Theoretical study and design of multifunctional phosphorescent platinum(ii) complexes containing triarylboron moieties for efficient OLED emitters
Authors: Wu Yong , Shan Guo-Gang , Li Hai-Bin , Wu Shui-Xing , Ren Xin-Yao , Geng Yun , Su Zhong-Min
Published: January 2015

Correction for ‘Theoretical study and design of multifunctional phosphorescent platinum(ii) complexes containing triarylboron moieties for efficient OLED emitters’ by Yong Wu et al., Phys. Chem. Chem. Phys., 2015, DOI: 10.1039/c4cp04919e.
A salen-type Dy4 single-molecule magnet with an enhanced energy barrier and its analogues
Authors: Luan Fang , Yan Pengfei , Zhu Jing , Liu Tianqi , Zou Xiaoyan , Li Guangming
Published: January 2015

A discrete hexadentate salen-type tetranuclear Dy complex with a unique {Ln4O8} core exhibits two slow magnetic relaxations with the highest energy barrier of 48.14 K among the reported tetranuclear salen-type dysprosium SMMs.
Synthesis and characterisation of nickel Schiff base complexes containing the meso-1,2-diphenylethylenediamine moiety: selective interactions with a tetramolecular DNA quadruplex
Authors: Davis Kimberley J. , Richardson Christopher , Beck Jennifer L. , Knowles Brett M. , Guédin Aurore , Mergny Jean-Louis , Willis Anthony C. , Ralph Stephen F.
Published: January 2015

Two nickel(ii) Schiff base complexes exhibit binding selectivity for a tetramolecular DNA quadruplex.
An N-heterocyclic carbene phenanthroline ligand: synthesis, multi-metal coordination and spectroscopic studies
Authors: Webster Alyssa A. , Prasad Shyamal K. K. , Hodgkiss Justin M. , Hoberg John O.
Published: January 2015

Dimetal complexes of a new N-heterocyclic carbene/phenanthroline ligand have been synthesized.
Facile preparation and bifunctional imaging of Eu-doped GdPO4 nanorods with MRI and cellular luminescence
Authors: Du Qijun , Huang Zhongbing , Wu Zhi , Meng Xianwei , Yin Guangfu , Gao Fabao , Wang Lei
Published: January 2015

Eu-doped GdPO4 NRs coated by silk fibroin have been prepared in a template of silk fibroin (SF) peptides via a mineralization process. A growth mechanism of SF-NRs is proposed to explain their stronger luminescence, better cyto-compatibility and higher longitudinal relaxivity r1.
A highly stable indium phosphonocarboxylate framework as a multifunctional sensor for Cu2+ and methylviologen ions
Authors: Dan Wenyan , Liu Xiaofeng , Deng Mingli , Ling Yun , Chen Zhenxia , Zhou Yaming
Published: January 2015

An indium phosphonocarboxylate framework (InPCF-1) with a novel 3,4,5-connected topology was synthesized, which serves as a selective and sensitive sensor for Cu2+ and MV2+ ions.
Diverse structures of metal–organic frameworks based on different metal ions: luminescence and gas adsorption properties
Authors: Zhang Chuan-Lei , Qin Ling , Shi Zhen-Zhen , Zheng He-Gen
Published: January 2015

Diverse structures of metal–organic frameworks induced by different metal ions under solvothermal conditions exhibit different topological characteristics and spectral properties.
Online solid sampling platform using multi-wall carbon nanotube assisted matrix solid phase dispersion for mercury speciation in fish by HPLC-ICP-MS
Authors: Deng Dongyan , Zhang Shu , Chen He , Yang Lu , Yin Hui , Hou Xiandeng , Zheng Chengbin
Published: January 2015

A method using multi-wall carbon nanotubes assisted matrix solid phase dispersion was developed to couple with HPLC-ICP-MS for mercury speciation.
Analysis of the hierarchical structure of the B. subtilis transcriptional regulatory network
Authors: Kumar Santhust , Vendruscolo Michele , Singh Amit , Kumar Dhiraj , Samal Areejit
Published: January 2015

Hierarchical decomposition of transcriptional regulators into Top, Middle and Bottom levels in theB. subtilistranscriptional regulatory network.
Facile synthesis of spinous-like Au nanostructures for unique localized surface plasmon resonance and surface-enhanced Raman scattering
Authors: Zhang Yan , Wang Bingyu , Yang Shihe , Li Lidong , Guo Lin
Published: January 2015

Spinous-like gold nanostructures were prepared using a wet chemistry method, and the intensities of the UV-Vis and SERS signals of the nanostructures were determined to be greatly enhanced by the presence of the spinous shapes.
Organocatalytic oxa-Diels–Alder reaction of α,β-unsaturated ketones under non-classical conditions
Authors: Mojzesová Melinda , Mečiarová Mária , Marti Roger , Šebesta Radovan
Published: January 2015

Non-classical activation techniques improve the organocatalysed oxa-Diels–Alder reaction of aldehydes with enones.
Nonradiative energy transfer in colloidal CdSe nanoplatelet films
Authors: Guzelturk Burak , Olutas Murat , Delikanli Savas , Kelestemur Yusuf , Erdem Onur , Demir Hilmi Volkan
Published: January 2015

In this study, nonradiative energy transfer was investigated in solid thin films of colloidal nanoplatelets incorporating two different vertical thicknesses.
Silver nanocube aggregation gradient materials in search for total internal reflection with high phase sensitivity
Authors: König Tobias A. F. , Ledin Petr A. , Russell Michael , Geldmeier Jeffrey A. , Mahmoud Mahmoud. A. , El-Sayed Mostafa A. , Tsukruk Vladimir V.
Published: January 2015

We fabricated monolayers of AgNC aggregations gradient with low surface coverage via LB deposition for broadband light absorption, which depends on the relative orientation of the aggregates to light polarization.
A comparative investigation on the effects of nitrogen-doping into graphene on enhancing the electrochemical performance of SnO2/graphene for sodium-ion batteries
Authors: Xie Xiuqiang , Su Dawei , Zhang Jinqiang , Chen Shuangqiang , Mondal Anjon Kumar , Wang Guoxiu
Published: January 2015

Enhanced electron transfer efficiency plays a dominant role for improving the performance of SnO2/N-doped graphene for sodium-ion batteries.
Gas phase chemistry of N-benzylbenzamides with silver(i) cations: characterization of benzylsilver cation
Authors: Sun Hezhi , Jin Zhe , Quan Hong , Sun Cuirong , Pan Yuanjiang
Published: January 2015

Benzylsilver cations are synthesized in the gas phase from the collisional dissociation of argentinatedN-benzylbenzamides, when the carbonyl oxygen nucleophilically attacks an α-hydrogen.
Alkylidene malonates and α,β-unsaturated α′-hydroxyketones as practical substrates for vinylogous Friedel–Crafts alkylations in water catalysed by scandium(iii) triflate/SDS
Authors: Oelerich Jens , Roelfes Gerard
Published: January 2015

Alkylidene malonates and α,β-unsaturated α′-hydroxyketones are excellent substrates for the Sc(OTf)3/SDS catalysed Friedel–Crafts alkylation in water.
Validating the alkene and alkyne hydrophosphonylation as an entry to organophosphonates
Authors: Dondoni Alessandro , Marra Alberto
Published: January 2015

The hydrophosphonylation of terminal alkenes and alkynes by H-phosphonates affords Markovnikov and/or anti-Markovnikov adducts depending on the catalyst (a metal or a radical initiator) and the reaction conditions.
Templating carbohydrate-functionalised polymer-scaffolded dynamic combinatorial libraries with lectins
Authors: Mahon Clare S. , Fascione Martin A. , Sakonsinsiri Chadamas , McAllister Tom E. , Bruce Turnbull W. , Fulton David A.
Published: January 2015

The templation of carbohydrate-functionalised Polymer-Scaffolded Dynamic Combinatorial Libraries affords polymers possessing significantly enhanced affinities for the template, with enhancements in free energy of binding in the range of 5.2–8.8 kJ mol−1 observed.
Secondary amine based ionic liquid: an efficient catalyst for solvent free one pot synthesis of xanthenes and benzoxanthenes
Authors: Das Pranab J. , Das Jupitara
Published: January 2015

Amine based ionic liquid was reported as an efficient and easily recyclable catalyst for the solvent free environmental benign synthesis of xanthene and benzoxanthene derivatives within 10–30 minutes.
Usage of different vessel models in a flow-through cell: in vitro study of a novel coated balloon catheter
Authors: Bandomir Jenny , Kaule Sebastian , Schmitz Klaus-Peter , Sternberg Katrin , Petersen Svea , Kragl Udo
Published: January 2015

Calcium alginate and polyacrylamide hydrogels were used as tissue models for the simulated anatomic implantation process.
Improved performance of lipases immobilized on heterofunctional octyl-glyoxyl agarose beads
Authors: Rueda Nazzoly , dos Santos Jose C. S. , Torres Rodrigo , Ortiz Claudia , Barbosa Oveimar , Fernandez-Lafuente Roberto
Published: January 2015

A new heterofunctional support, octyl-glyoxyl agarose, is proposed in this study.
Structural and magnetic properties of tetragonal perovskite BaFe1−xBixO3−δ
Authors: Farid Muhammad Asim , Zhang Hao , Lin Xiaohuan , Yang Aimei , Yang Sihai , Li Guobao , Liao Fuhui , Lin Jianhua
Published: January 2015

BaFe1−xBixO3−δ (0.09 ≤ x ≤ 0.35) crystallizes in P4/mmm confirmed by the combinational use of powder X-ray, synchrotron, neutron and electron diffractions with the antiferromagnetic transition occurring from 64 to 50 K.
A green method to prepare TiO2/MWCNT nanocomposites with high photocatalytic activity and insights into the effect of heat treatment on photocatalytic activity
Authors: Zeng Qingping , Li Hua , Duan Huanan , Guo Yiping , Liu Xuefa , Zhang Yangyang , Liu Hezhou
Published: January 2015

We demonstrate a green method to prepare TiO2/MWCNT with uniform loading and high photocatalytic activity, and study the effect of heat treatment on the photocatalytic activity.
Examining the compatibility of collagen and a polythiophene derivative for the preparation of bioactive platforms
Authors: Soto-Delgado Jorge , Torras Juan , del Valle Luis J. , Estrany Francesc , Alemán Carlos
Published: January 2015

Poly(3,4-ethylenedioxythiophene) and collagen interact specifically forming biocomposites that mimic the growing of biological tissues.
Hierarchical hollow TiO2@CeO2 nanocube heterostructures for photocatalytic detoxification of cyanide
Authors: Liu Yongjun , Li Tingting , Chen Weiwei , Guo Yuanyuan , Liu Lixiang , Guo Hong
Published: January 2015

Hollow TiO2@CeO2 nanocubes are fabricated via a fast coordinating etching route. The hollow cubic nature and heterojunction effect of the nanostructure contribute greatly to the enhanced performance for photocatalytic detoxification of cyanide.
The effect of the selenization process on grain size and performance of CuIn(Sx,Se1−x)2 counter electrodes
Authors: Zhang Yan-zhu , Li Huan-huan , Zhou Zheng-ji , Kou Dong-xing , Zhou Wen-hui , Wu Si-xin
Published: January 2015

Rapid heating selenization is beneficial to the formation of well crystalline CISSe film with large grains and excellent electrocatalytic activity.
Structural characterization of α-amino acid complexes of molybdates: a spectroscopic and DFT study
Authors: Biancalana Lorenzo , Bortoluzzi Marco , Forte Claudia , Marchetti Fabio , Pampaloni Guido
Published: January 2015

A joint spectroscopic and computational study has allowed us to determine the dinuclear structural core of the products of the reactions between molybdates and α-amino acids in aqueous medium.
Fabrication of zein/quaternized chitosan nanoparticles for the encapsulation and protection of curcumin
Authors: Liang Hongshan , Zhou Bin , He Lei , An Yaping , Lin Liufeng , Li Yan , Liu Shilin , Chen Yijie , Li Bin
Published: January 2015

In this article, we report the successful assembly of nanoparticles (NPs) from a water-soluble chitosan (CS) derivative (N-(2-hydroxyl)propyl-3-trimethyl ammonium chitosan chloride, HTCC) and zein via a low-energy phase separation method.
Co-precipitation with calcium carbonate – a fast and nontoxic method for removal of nanopollutants from water?
Authors: Mallampati Ramakrishna , Valiyaveettil Suresh
Published: January 2015

A simple, scalable and environmentally friendly coprecipitation method using CaCO3 is reported for the removal of nanopollutants from water.
Hydrophobic mesoporous silica-supported heteropolyacid induced by ionic liquid as a high efficiency catalyst for the oxidative desulfurization of fuel
Authors: Xiong Jun , Zhu Wenshuai , Ding Wenjing , Yang Lei , Zhang Ming , Jiang Wei , Zhao Zhen , Li Huaming
Published: January 2015

The hydrophobic HPMo-IL/SBA-15 material served not only as a high-efficiency catalyst but also as an adsorbent.
Sonochemical synthesis of reduced graphene oxide uniformly decorated with hierarchical ZnS nanospheres and its enhanced photocatalytic activities
Authors: Golsheikh A. Moradi , Lim H. N. , Zakaria Rozalina , Huang N. M.
Published: January 2015

Reduced graphene oxide decorated with ZnS nanospheres was synthesized through the simple ultrasonic irradiation route which shows a significant enhancement in the photocatalytic degradation of methylene blue compared to the bare ZnS particles.
Synthesis of a 2,4,6,8,10-dodecapentanoic acid thioester as a substrate for biosynthesis of heat stable antifungal factor (HSAF)
Authors: Olson Andrew S. , Chen Haotong , Du Liangcheng , Dussault Patrick H.
Published: January 2015

The N-acetylcystamine thioester of dodecapentaenoic acid is synthesized. The thioester is investigated as a biosynthetic substrate and was not incorporated in the observed products.
Synthesis of hierarchical ferrierite using piperidine and tetramethylammonium hydroxide as cooperative structure-directing agents
Authors: Xue Teng , Liu Huaping , Wang Yi Meng
Published: January 2015

Zeolite ferrierite aggregates with hierarchical porosity were synthesized using TMAOH and piperidine as cooperative structure-directing agents (co-SDAs).
New insights into the effects of NaCl and LiCl on the hydrogen storage behaviours of a 6LiBH4–Mg(AlH4)2composite
Authors: Pang Yuepeng , Liu Yongfeng , Zhang Xin , Li You , Gao Mingxia , Pan Hongge
Published: January 2015

The presence of NaCl and LiCl changes the dehydrogenation/hydrogenation kinetics of the 6LiBH4–Mg(AlH4)2composite.
Formation of NaP zeolite from fused fly ash for the removal of Cu(ii) by an improved hydrothermal method
Authors: Deng Hui , Ge Yan
Published: January 2015

Fly ash with a Si : Al ratio of 3.63 has been converted to a zeolite of high Cu2+ sorption capacity using a fusion conversion process and an improved hydrothermal method.
Computer investigations of influences of molar fraction and acyl chain length of lipids on the nanoparticle–biomembrane interactions
Authors: Li Yang
Published: January 2015

Structural variations of the heterogeneous membrane: (a) a water defect, (b) the membrane buckling.
Spectroscopic signatures and structural motifs in isolated and hydrated theophylline: a computational study
Authors: Singh Vipin Bahadur
Published: January 2015

Optimized geometry of newly characterized theophylline dimer Form IV at MP2/6-311++G(d,p) level.
Impact of linker in polypyrrole/quinone conducting redox polymers
Authors: Karlsson Christoffer , Huang Hao , Strømme Maria , Gogoll Adolf , Sjödin Martin
Published: January 2015

Introducing a linker unit in polypyrrole/quinone conducting redox polymers dramatically reduces the interaction between the two redox systems. Moreover, increasing its length and flexibility completely eliminates the interaction.
Large area quantitative analysis of nanostructured thin-films
Authors: Sliz Rafal , Eneh Chibuzor , Suzuki Yuji , Czajkowski Jakub , Fabritius Tapio , Kathirgamanathan Poopathy , Nathan Arokia , Myllyla Risto , Jabbour Ghassan
Published: January 2015

Proposed and verified method offers an unique quantitative large scale nanostructures' evaluation.
Fluorescent/laser dual-channel ATP sensors based on flavins
Authors: Liu Yu , Li Peng , Ma Hongwei , Zhang Ming , Li Feng
Published: January 2015

The fluorescence biomolecules flavin mononucleotide and lumiflavin were demonstrated as ATP sensors for the first time.
Comparative evaluation of the blends of gas-to-liquid (GTL) fuels and biodiesels with diesel at high idling conditions: an in-depth analysis on engine performance and environment pollutants
Authors: Hossain S. , Masjuki H. H. , Varman M. , Kalam M. A. , Rahman S. M. Ashrafur
Published: January 2015

The effect of high-idling conditions at different engine performance-emission parameters were investigated using blends of GTL–diesel and biodiesel–diesel.
One pot selective synthesis of water and organic soluble carbon dots with green fluorescence emission
Authors: Zheng Baozhan , Liu Tao , Paau Man Chin , Wang Meina , Liu Yang , Liu Lizhen , Wu Chuanfang , Du Juan , Xiao Dan , Choi Martin M. F.
Published: January 2015

This work reports a simple and energy-saving strategy for selective synthesis of water-soluble and organic-soluble carbon dots at room temperature.