bluuebunny/crossref_metadata_2025 huggingface dataset:
Attitudes of University Students towards Mandatory COVID-19 Vaccination Policies: A Cross-Sectional Survey in Rome, Italy
Authors: Sciurti Antonio , Baccolini Valentina , Renzi Erika , De Blasiis Maria Roberta , Siena Leonardo Maria , Isonne Claudia , Migliara Giuseppe , Massimi Azzurra , De Vito Corrado , Marzuillo Carolina , Villari Paolo
Published: March 2023

Mandatory vaccination (MV) against COVID-19 is a contentious topic. In this study, we used logistic regression models to identify attitudes among Sapienza University students towards MV for COVID-19. We considered three different scenarios: mandatory COVID-19 vaccination (MCV) for healthcare workers (HCWs) (Model 1), for all people aged ≥ 12 years (Model 2), and for admission to schools and universities (Model 3). We collected 5287 questionnaires over a six-month period and divided these into three groups (September–October 2021, November–December 2021, and January–February 2022). MCV for HCWs was the most strongly supported policy (69.8% in favour), followed by MCV for admission to schools and universities (58.3%), and MCV for the general population (54.6%). In a multivariable analysis, the models showed both similarities and differences. There was no association of socio-demographic characteristics with the outcomes, apart from being enrolled in non-healthcare courses, which negatively affected Models 2 and 3. A greater COVID-19 risk perception was generally associated with a more positive attitude towards MCV, although heterogeneously across models. Vaccination status was a predictor of being in favour of MCV for HCWs, whereas being surveyed in November–February 2022 favoured MCV for admission to schools and universities. Attitudes towards MCV were variable across policies; thus, to avoid unintended consequences, these aspects should be carefully considered by policymakers.
Mathematical Modeling Evaluates How Vaccinations Affected the Course of COVID-19 Disease Progression
Authors: Tzamali Eleftheria , Sakkalis Vangelis , Tzedakis Georgios , Spanakis Emmanouil G. , Tzanakis Nikos
Published: March 2023

The regulation policies implemented, the characteristics of vaccines, and the evolution of the virus continue to play a significant role in the progression of the SARS-CoV-2 pandemic. Numerous research articles have proposed using mathematical models to predict the outcomes of different scenarios, with the aim of improving awareness and informing policy-making. In this work, we propose an expansion to the classical SEIR epidemiological model that is designed to fit the complex epidemiological data of COVID-19. The model includes compartments for vaccinated, asymptomatic, hospitalized, and deceased individuals, splitting the population into two branches based on the severity of progression. In order to investigate the impact of the vaccination program on the spread of COVID-19 in Greece, this study takes into account the realistic vaccination program implemented in Greece, which includes various vaccination rates, different dosages, and the administration of booster shots. It also examines for the first time policy scenarios at crucial time-intervention points for Greece. In particular, we explore how alterations in the vaccination rate, immunity loss, and relaxation of measures regarding the vaccinated individuals affect the dynamics of COVID-19 spread. The modeling parameters revealed an alarming increase in the death rate during the dominance of the delta variant and before the initiation of the booster shot program in Greece. The existing probability of vaccinated people becoming infected and transmitting the virus sets them as catalytic players in COVID-19 progression. Overall, the modeling observations showcase how the criticism of different intervention measures, the vaccination program, and the virus evolution has been present throughout the various stages of the pandemic. As long as immunity declines, new variants emerge, and vaccine protection in reducing transmission remains incompetent; monitoring the complex vaccine and virus evolution is critical to respond proactively in the future.
Humoral Response in Hemodialysis Patients Post-SARS-CoV-2 mRNA Vaccination: A Systematic Review of Literature
Authors: Notarte Kin Israel , Catahay Jesus Alfonso , Peligro Princess Juneire , Velasco Jacqueline Veronica , Ver Abbygail Therese , Guerrero Jonathan Jaime , Liu Jin , Lippi Giuseppe , Benoit Stefanie W. , Henry Brandon Michael , Fernández-de-las-Peñas César
Published: March 2023

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), has infected over 600 million individuals and caused nearly 7 million deaths worldwide (10 January 2023). Patients with renal disease undergoing hemodialysis are among those most adversely affected, with an increased predisposition to SARS-CoV-2 infection and death. This systematic review aimed to pool evidence assessing the humoral response of hemodialysis patients (HDP) post-mRNA SARS-CoV-2 vaccination. A systematic search of the literature was performed through MEDLINE, CINAHL, PubMed, EMBASE, and Web of Science databases, as well as medRxiv and bioRxiv preprint servers up to 10 January 2023. Cohort and case-control studies were included if they reported an immune response in one group of patients undergoing hemodialysis who received mRNA SARS-CoV-2 vaccination compared with another group of patients receiving the same vaccine but not on hemodialysis. The methodological quality was assessed using the Newcastle-Ottawa Scale. Meta-analysis was not deemed appropriate due to the high heterogeneity between studies. From the 120 studies identified, nine (n = 1969 participants) met the inclusion criteria. Most studies (n = 8/9, 88%) were of high or medium methodological quality (≥6/9 stars). The results revealed that HDP developed lower antibody levels across all timepoints post-vaccination when compared with controls. Patients with chronic kidney disease elicited the highest antibody immune response, followed by HDP and, lastly, kidney transplant recipients. Overall, post-vaccination antibody titers were comparatively lower than in the healthy population. Current results imply that robust vaccination strategies are needed to address waning immune responses in vulnerable populations.
Fluvial Hydraulics Affected by River Ice and Hydraulic Structures
Authors: Sui Jueyi
Published: March 2023

Water on earth moves from one place to another by way of hydrologic processes such as precipitation, runoff, infiltration, evapotranspiration, melting, and ground-water flow [...]
A Stacking Ensemble Model of Various Machine Learning Models for Daily Runoff Forecasting
Authors: Lu Mingshen , Hou Qinyao , Qin Shujing , Zhou Lihao , Hua Dong , Wang Xiaoxia , Cheng Lei
Published: March 2023

Improving the accuracy and stability of daily runoff prediction is crucial for effective water resource management and flood control. This study proposed a novel stacking ensemble learning model based on attention mechanism for the daily runoff prediction. The proposed model has a two-layer structure with the base model and the meta model. Three machine learning models, namely random forest (RF), adaptive boosting (AdaBoost), and extreme gradient boosting (XGB) are used as the base models. The attention mechanism is used as the meta model to integrate the output of the base model to obtain predictions. The proposed model is applied to predict the daily inflow to Fuchun River Reservoir in the Qiantang River basin. The results show that the proposed model outperforms the base models and other ensemble models in terms of prediction accuracy. Compared with the XGB and weighted averaging ensemble (WAE) models, the proposed model has a 10.22% and 8.54% increase in Nash–Sutcliffe efficiency (NSE), an 18.52% and 16.38% reduction in root mean square error (RMSE), a 28.17% and 18.66% reduction in mean absolute error (MAE), and a 4.54% and 4.19% increase in correlation coefficient (r). The proposed model significantly outperforms the base model and simple stacking model indicated by both the Friedman test and the Nemenyi test. Thus, the proposed model can produce reasonable and accurate prediction of the reservoir inflow, which is of great strategic significance and application value in formulating the rational allocation and optimal operation of water resources and improving the breadth and depth of hydrological forecasting integrated services.
How to Incorporate System Archetypes into Water Conflicts Analysis: Application in Euphrates, Nile, Zambezi, and Lake Kivu Transboundary Basins
Authors: Shahbazbegian Mohammadreza , Nabavi Ehsan
Published: March 2023

This paper introduces and fleshes out a systemic method designed to develop a holistic understanding of states’ behavior in transboundary water conflict and cooperation. Such an approach leverages causality analysis to capture the deep structural characteristics that shape the hydropolitics dynamics and may lead to the evolution of destructive behaviors with severe consequences. The paper does so by using the concepts of the system archetype. The system archetype analysis offers insight into the underlying structures from which the dynamics of hydropolitics emerge over time—cycles of conflict and cooperation. The approach provides riparian states with a diagnostic tool to recognize patterns of destructive behaviors in the management of shared water resources and warning signs that are usually too long overlooked. Using four case studies from different continents, this paper shows how a systems archetype approach is useful for developing a big-picture understanding of the hydropolitical problem, its dynamics, and potential resolution pathways. The systemic lessons learned from these case studies can be used in other contexts, helping policymakers anticipate the destructive and constructive dynamics leading to conflict and cooperation.
Ammonia-Nitrogen Removal by Hydroxyapatite Prepared from Waste Fish Scale
Authors: Wang Haoru , Qian Mingjie , Zhang Dongchen , Wu Qiaoling , Zhao Zengying
Published: March 2023

The pollution of ammonia-nitrogen in water became more serious with the development of the industry. In this paper, hydroxyapatite (HAP) was prepared from waste fish scales; the XRD, FTIR, SEM, TEM and Raman were used to characterize the prepared samples, and the prepared HAP samples were studied as degradation photocatalyst and adsorbing material for the removal of ammonia-nitrogen. The ammonia-nitrogen removal efficiency (ANRE, Removal Rate = (Initial Concentration–Current Concentration)/Initial Concentration × 100%) of the samples was also discussed. The results showed that the HAP sample, which was calcinated at 800 °C for 2 h, had the best ANRE, which was 41%. The UV-Vis, EIS, and PL were used to analyze the reason for the different ANRE. The reason for the high ANRE was attributed to the samples’ superior adsorption capability resulting from their large specific surface area, as well as their superior properties for photocatalytic degradation. This was a meaningful work to explore a treatment of ammonia-nitrogen by HAP.
Optimal Near Real-Time Control of Water Distribution System Operations
Authors: Bin Mahmoud Abdulrahman Abdulaziz , Momeni Ahmad , Piratla Kalyan Ram
Published: March 2023

The scarcity of freshwater resources, combined with deteriorating infrastructure, pushes water utilities to employ optimal operational practices to control water distribution systems (WDSs) based on objectives such as minimizing operational costs or leakages. This paper demonstrates a metaheuristic optimization framework for controlling WDS operations in near real-time by minimizing the total energy consumption, while maintaining sustainable system conditions and operations, such as those of tanks. The proposed framework, at its core, comprises a water demand forecasting model, an optimization-based control model, and a hydraulic continuity model. The hypothesis is that WDS can be controlled more efficiently by forecasting and predicting the near future system conditions based on past and prevailing conditions. Operational time steps of 60, 30, and 15 min are considered, to evaluate the benefits of using shorter operational time steps than the conventional norm. The proposed framework is demonstrated using a small-sized benchmark WDS. The results revealed that real-time control schemes reduce the operational costs of the selected WDS by up to 17.8%, with the shortest time step scheme (15 min) offering the most reduction in operational expenses, at the cost of more computational expensiveness. This study and its findings would help utilities plan more reliable and sustainable operational schemes.
Investigation and Development of the Brushless and Magnetless Wound Field Synchronous Motor Drive System for Electric Vehicle Application
Authors: Li Yanhui , Wang Yiwei , Zhang Zhuoran , Li Jincai
Published: March 2023

In order to solve the problems of soaring costs and supply fluctuation in permanent magnet materials, this paper investigates and develops a magnetless wound field synchronous motor (WFSM) drive system for electric vehicle (EV) application. As the crucial drive component for EVs, the proposed WFSM in this paper has a two-stage structure which is described as the exciter and the main motor. The excitation characteristics of the exciter that provide power to the rotor field winding are emphatically analyzed. In addition, the discrete time domain armature current regulator and excitation current regulator are designed and analyzed for the high-performance WFSM drive system. A current coordinated control strategy for the full speed range is proposed to expand the constant power region. The experiment shows that the excitation characteristics and torque capability of the WFSM are consistent with the analysis, and proves that the WFSM is a potential solution for the magnetless motor for EV application.
APPROACH TO ACCOUNTING PARAMETERS, APPLYING METHODS OF CHOICE FOR UNCERTAIN ALTERNATIVES
Authors:   Saint Petersburg Mining University, Alexander Grigorievich Matveev , Tatyana Anatolyevna Menuhova ,   Saint Petersburg Mining University
Published: March 2023

In the process of making management decisions in order to improve the efficiency of enterprises, decision makers often resort to evaluating various conditions, equipment, routes, development strategies, etc. using methods for choosing alternatives under conditions of uncertainty. This article proposes an alternative approach to the existing one, applicable to many existing decision methods, capable of taking into account parameters with fixed reference values and minimum reference values. The algorithm of the proposed approach is demonstrated on the example of the choice of a vehicle.
SPECIAL VEHICLE FUNCTIONAL PART MATHEMATICAL MODEL DEVELOPMENT
Authors:   Moscow Automobile and Road Construction State Technical University (MADI), Dmitriy Aleksandrovich Nikitin
Published: March 2023

The article discusses the features of the operation of the airfield. The basic principles of operation of special purpose vehicles when cleaning runways in winter are given. The special importance of productivity and quality of work performed on the territory of the airfield, performed with the use of a brush unit, is determined. The main structural elements and drive systems of the central brush of a special cleaning car are revealed. As a result of the research, the main structural elements and the drive system of the cylindrical brush, lifting and clamping mechanism have been developed.
THE CONCEPT OF A METHODOLOGY TO IMPROVE ROAD SAFETY BY PROVIDING A SAFE ROUTE FOR USERS OF PERSONAL TRANSPORTERS
Authors:   Moscow Automobile and Road Construction State  Technical University, Sultan Vladimirovich Zhankaziev , Marina Nikolaevna Vrazhnova ,   Moscow Automobile and Road Construction State  Technical University, Anastasiya Andreevna Pashkova ,   Moscow Automobile and Road Construction State  Technical University
Published: March 2023

The paper deals with personal transporters and their main technical characteristics. The statistics of accidents involving personal transporters in the territory of the Russian Federation for 9 months of the last three years is analyzed. The analysis of traffic parameters in terms of errors of the first and second kind is carried out. A concept of route guidance methods for users of personal transporters by constructing a safe route was offered. The results of this study will be used to de-velop a smartphone application for users of personal transporters.
EXPERIENCE IN THE IMPLEMENTATION OF PUBLIC TRANSPORT COORDINATION SYSTEMS ON THE EXAMPLE OF THE OREL URBAN AGGLOMERATION
Authors:   NAVIGATOR Group of Companies, Aleksandr Nikolayevich Semkin , Aleksandr Nikolayevich Shevlyakov ,   NAVIGATOR Group of Companies
Published: March 2023

The authors of the article give examples of the practical implementation of an ecosystem that includes technological products for management, modeling and interactive interaction of participants in the urban passenger transportation system. the problems of their implementation are described, the architecture of the module that coordinates the work of public transport is developed, the results of the implementation of subsystems for coordinating the movement of route vehicles are presented, recommendations for the further development of the implemented subsystems are given.
DEVELOPMENT OF TRAFFIC MANAGEMENT METHODS IN SMALL AND MEDIUM CITIES
Authors:   Voronezh State Forest Engineering University, Sergey Vladimirovich Dorokhin , Alexander Yurievich Artemov ,   Voronezh State Forest Engineering University
Published: March 2023

The article is devoted to the development of traffic flow management methods in urban transport systems of small and medium-sized cities. Certain conditions for managing traffic flows, typical for small and medium-sized cities, require the development of methods used today. In order to improve management efficiency, in particular, the use of coordinated management of main streets, within the framework of this study, the movement process was modeled and the delay time was estimated when the intensity changed at the object of study. The analysis of the obtained results made it possible to establish certain dependencies and identify specialized areas in which it is necessary to change the type of management used.
IMPROVEMENT OF TRAFFIC IN THE CITY OF KRASNOYARSK ON THE BASIS OF INTELLIGENT TRANSPORT TECHNOLOGIES
Authors:   Krasnoyarsk kray Administration, Sergey Vasilyevich Eremin , Alexander Nikolaevich Novikov ,   Orel State University, Larisa Yurevna Frolenkova ,   Orel State University, Andrei Vladimirovich Kulev ,   Orel State University, Maksim Vladimirovich Kulev ,   Orel State University
Published: March 2023

The paper discusses the issues of improving the efficiency of traffic management based on intelligent transport technologies. The proposed methodology is based on the developed factor model of maximizing the capacity of a section of the road network, which allows to establish the relationship between the values of traffic flow intensities in different directions. The practical implementation of the proposed measures is carried out on the example of the intersection of Aca-demician Kirensky and Kopylov streets in the city of Krasnoyarsk. The initial data for modeling were obtained using subsystems and modules of the intelligent transport system of the city.
DETERMINATION OF THE DYNAMIC INDICATOR OF THE CAR IN THE TRAFFIC FLOWS OF THE URBAN TRANSPORT SYSTEM
Authors:   Belgorod State Technologica lUniversity, Alina Gennadievna Loktionova , Anastasia Gennadievna Shevtsova ,   Belgorod State Technological University
Published: March 2023

This article defines a dynamic indicator, namely the acceleration of a car, for an improved calculated - calibrated car based on research, technical and geometric parameters of frequently encountered passenger vehicles in urban traffic.
PROSPECTS FOR THE DEVELOPMENT OF TRANSPORT ACCESSIBILITY IN THE ARCTIC ULUSES OF THE REPUBLIC OF SAKHA (YAKUTIA)
Authors:   Moscow Automobile and Road Construction State  Technical University, Nadezhda Anatolievna Filippova , Anna Egorovna Ivanova ,   North-Eastern Federal University, Alexander Mikhailovich Ishkov ,   North-Eastern Federal University
Published: March 2023

The article discusses the prospects for the development of transport accessibility of the Arctic uluses of the Republic of Sakha (Yakutia). The main characteristics of the bridge crossing over the Lena River are given and the improved indicators are described when it is put into operation.
TO THE QUESTION OF MATHEMATICAL STATEMENT OF THE PROBLEM OF OPTIMIZATION OF ROUTES OF CARGO MULTIMODAL TRANSPORTATION
Authors:   South-Russian State Polytechnic University, Valeria Evgenjevna Yarkina , Evgeny Kuzmich Yarkin ,   South-Russian State Polytechnic University
Published: March 2023

The article deals with the urgent task of increasing the efficiency of multimodal transportation of goods based on the optimization of delivery routes. The task is formulated in terms of the subject area of interest to the transportation customer. The mathematical statement of the problem is presented in the form of a graph model that takes into account dynamic changes in the requirements of both the consignor and the consignee. According to the authors, this approach to solving the logistics problem allows the multimodal operator to respond to changes in a timely manner and gives some advantages when choosing an effective route in the face of sanctions pres-sure and border closures.
DECISION SUPPORT SYSTEM FOR THE MANAGEMENT OF THE TECHNICAL OPERATION OF ROAD TRANSPORT
Authors:   Tyumen Industrial University, Evgeniy Sergeevich Kozin , Artem Vladimirovich Bazanov ,   Tyumen Industrial University
Published: March 2023

The article deals with the issues of introduction and use of information technologies in the field of technical operation of road transport. The article presents in detail the block of simulation modeling of the processes of operation of the fleet of vehicles and the area of car repair.
PECULIARITIES OF SELF-ATTITUDE OF EDUCATIONISTS WITH DIFFERENT LEVELS OF EMOTIONAL BURNOUT
Authors: Metelska N.
Published: March 2023

The article presents the results of an empirical study of the problem of emotional burnout of pedagogues. In particular, an analysis of the peculiarities of self-attitude of educationists with different levels of emotional burnout is made.

The nature of the connection between the level of emotional burnout of educationists and the peculiarities of their professional self-consciousness, in particular self-attitude as one of the components of a specialist’s self-consciousness, is analyzed. The results of the comparative study proved that inspite rather high indicators of self-approval and positive self-esteem, the studied pedagogues are not sure that their personality is interesting for others, and they are also convinced that other people and colleagues are not interested in them. We came to the conclusion that most of the symptoms and phases of emotional burnout are not formed within the group of the studied educationists, but they are characterized with a certain emotional closedness, aloofness and indifference, which can be an indicator of their emotional exhaustion, and against this background any emotional involvement into professional affairs and communications can cause the feeling of excessive fatigue of pedagogues.

The results of a comparative analysis of peculiarities of the self-attitude of educationists with different levels of emotional burnout indicate a general high level of self-attitude of the subjects, but do not exclude the formation of professional deformations of them. In general, it was found that a high level of positive self-attitude of educationists correlates with a low level of manifestation of symptoms and phases of burnout in their professional activities. Educationists with a positive self-attitude are less likely to feel emotional exhaustion, fatigue, and desolation caused by professional activity. In addition, pedagogues with positive self-attitude are less likely to experience the leveling of professional achievements, disruption of professional communications, dissatisfaction with themselves as professionals and their own professional activity, as well as psychosomatic diseases, perception of the conditions of professional activity and interpersonal relationships in the professional area as psychologically traumatic.
Swedish LGBTQ Activists’ Responses to Neo-Nazi Threats:
Authors: Linander Ida , Lauri Johanna , Lauri Marcus
Published: March 2023

LGBTQ communities and movements across Europe are under attack from various conservative and right-wing extremist groups. What are the political implications of such attacks for LGBTQ activists? Through qualitative interviews and psychoanalytical discourse theory, this article analyses LGBTQ activists’ responses to threats from neo-Nazis in Sweden. By focusing on the problems, solutions and desires articulated by LGBTQ activists, the analysis asks: Who is called upon to handle the neo-Nazis, and how? What fantasies are expressed in such articulations? How may the response to neo-Nazis shape the subjectivities and political aspirations of LGBTQ activists? The analysis shows that the activists adhere to a fantasy of positive and conflict-free politics where the state is called upon to care for them through legal measures, which ties the activists to the state and might block other alliances. The activists also express a desire to inscribe themselves into the LGBTQ movement’s history. This fantasy echo might strengthen a political collective and prove pivotal in future struggles. Taken together, our analysis demonstrates some of the effects of the neo-Nazi presence in Sweden and some of the wider political implications for the LGBTQ movement.
Sodium magnetic resonance imaging shows impairment of the counter-current multiplication system in diabetic mice kidney
Authors: Nakagawa Yusuke , Kaseda Ryohei , Suzuki Yuya , Watanabe Hirofumi , Otsuka Tadashi , Yamamoto Suguru , Kaneko Yoshikatsu , Goto Shin , Terada Yasuhiko , Haishi Tomoyuki , Sasaki Susumu , Narita Ichiei
Published: March 2023

Background:

Sodium magnetic resonance imaging can non-invasively assess sodium distribution, specifically sodium concentration in the countercurrent multiplication system in the kidney, which forms a sodium concentration gradient from the cortex to the medulla, enabling efficient water reabsorption. This study aimed to investigate whether sodium magnetic resonance imaging can detect changes in sodium concentrations under normal conditions in mice and in disease models such as a mouse model with diabetes mellitus. Methods: We performed sodium and proton nuclear magnetic resonance imaging using a 9.4-T vertical standard-bore super-conducting magnet. Results: A condition of deep anesthesia, with widened breath intervals, or furosemide administration in 6-week-old C57BL/6JJcl mice showed a decrease in both tissue sodium concentrations in the medulla and sodium concentration gradients from the cortex to the medulla. Further, sodium magnetic resonance imaging revealed reductions in the sodium concentration of the medulla and in the gradient from the cortex to the medulla in BKS.Cg-Leprdb+/+ Leprdb/Jcl mice at very early type-2 diabetes mellitus stages compared to corresponding control BKS.Cg-m+/m+/Jcl mice. Conclusions: The kidneys of BKS.Cg-Leprdb+/+ Leprdb/Jcl mice aged 6 weeks showed impairments in the countercurrent multiplication system. We propose the utility of 23Na MRI for evaluating functional changes in diabetic kidney disease, not as markers that reflect structural damage. Thus, 23Na MRI may be a potential very early marker for structures beyond the glomerulus; this may prompt intervention with novel efficacious tubule-targeting therapies.
Adverse drug event trigger tool: construction and application of a readyto-use tool at Hue University of Medicine and Pharmacy Hospital
Authors: Phan Dang Thuc Anh , Pham Thi Nhan , Tran Quang Phuc , Phan Van Nam
Published: March 2023

Background: Adverse drug event (ADE) is one of the most common causes of injury to patients, accounting for 19% of adverse events (AEs), particularly among the elderly due to their sensitivity to ADE. Thus, taking ADE detection is the first vital step in improving medication safety. Objective: This study aimed to develop an appropriate modified triggers tool based on Institute for Healthcare Improvement (IHI) Global Trigger tool for Adverse Events detecting potential ADEs in patients at Hue University Hospital. Materials and methods: Using a retrospective study on the medical records of inpatients treated in Hue University of
Medicine and Pharmacy Hospital in 2020. Results: The modified ADE trigger tool encompassed 13 triggers. In the screening stage, the ADEs were found in 18 medical records (1.9% of total screening records), and 22 ADEs were identified, in which 19 ADEs were determined as adverse drug reactions (ADRs). The study also found that 17/19 ADRs had not been reported via a spontaneous reporting system (89.5%). The modified ADE Trigger tool’s positive predictive value (PPV) was 0.06. Conclusion: A modified ADE Trigger tool for detecting ADE has been constructed and applied at Hue University of Medicine and Pharmacy Hospital. This study would be the first motivation for further studies that attempt to apply this tool into daily clinical pharmacy activities and emphasize the role of Clinical Pharmacists at the hospital.
Key words: Adverse Drug Event, adverse event, geriatrics, clinical pharmacy.
Farklı Yönlendirmeli Bina Dış Duvarlarında Faz Değiştiren Malzeme Kullanımının Isı Kazancına Etkisinin Araştırılması
Authors: ÖZEL Meral , ÇAKMAK Fethi Ahmet
Published: March 2023

Bu çalışmada, farklı yönlere bakan bina dış duvarlarında geleneksel ısı yalıtım malzemesi yerine faz değiştiren malzeme (FDM) kullanılarak soğutma yükleri ANSYS Fluent programı ile nümerik olarak araştırılmıştır. Analizler iki boyutlu ve zamana bağlı olarak gerçekleştirilmiştir. Elazığ ilinin yaz iklim şartları göz önünde bulundurularak bina dış yüzeyinin 24 saat boyunca değişen güneş ışınımı ve dış ortam sıcaklıklarına maruz bırakıldığı iç yüzeyinin ise sabit sıcaklıkta oda havasıyla temasta olduğu kabul edilmiştir. Bu amaçla 5 farklı duvar modeli belirlenerek ilk olarak duvar kalınlığı boyunca sıcaklık dağılımları ve soğutma yükleri hesaplanmış ve daha sonra ise ısıl depolama kapasitelerini temsil eden faz kayması ve sönüm oranları tespit edilmiştir. Elde edilen sonuçlar mevcut yalıtım ile kıyaslanmıştır. Sonuç olarak, duvara yalıtım yerine aynı kalınlıkta FDM uygulanarak tüm duvar yönlendirmeleri için dış sıcaklık dalgalanmaları sönümlenip iç yüzey yayılımının en aza indirilmesi sağlanmıştır. Ayrıca duvara FDM uygulanarak maksimum faz kayması ve minimum sönüm oranı açısından duvarın ısı depolama kapasitesinin de arttığı görülmüştür. Faz değiştiren malzemenin dışta kullanılmasının daha verimli olduğu görülmüş ve yalıtımsız duvara göre iç yüzeyde 2oC daha düşük sıcaklık elde edilmiştir. Çalışmada kullanılan UDF (User-defined function) kodu sayesinde her bir saatteki sıcaklık değerleri değişken sınır şartı olarak verilmiştir.
AUDITORIA ENERGÉTICA COM ÊNFASE EM ILUMINAÇÃO E CONDICIONAMENTO AMBIENTAL PARA UNIDADE ACADÊMICA I DE UM INSTITUTO FEDERAL
Authors: LIMA SANTOS THAÍS , BARROS CASTOR DANIEL
Published: March 2023

Population growth imposes on society a pattern of intense consumption that generates a need for greater awareness and energy management. In order to bring improvements and manage resources in an intelligent and efficient way, this article will present a practical study of an energy audit in a public building located on the IFPB campus João Pessoa-PB with the intention of seeking viable solutions to reduce energy consumption. The approach adopted for waste analysis consists of a careful survey of data from all areas of the building, listing consumption items such as lighting, air conditioning, as well as various equipment. Then, technical calculations were made to improve environments and implement new equipment, as well as calculate the payback to inform how long the return on investment would be. Finally, it was found that the proposed changes to the studied system would bring a return in the short term and with a long period of profitability.
INFLUENCE OF ZHEZHELEVSKY GRANITE QUARRY WASTEWATER ON THE FORMATION OF PLANT COMMUNITIES
Authors: Medvid O. , Kotsiuba I. , Khomiak I.
Published: March 2023

The work is devoted to studying the impact of reclaimed water discharge on the dynamics and state of plant communities in the Zhezheliv granite quarry. The purpose of the study is to study the effect of return water on plant communities in the territory of the planned activity of the Private Joint-Stock Company "Zhezhelivsky Quarry". To achieve the goal, the following tasks were set: to investigate and classify plant groups in the territory of the planned activity of the Zhezheliv granite quarry; to establish the leading factors that change  during  the release of  return  waters;  to  predict the probable environmental impact of reclaimed waters on  rare components  of  the biota.  The territory of the Zhezheliv granite deposit is a typical anthropogenic landscape with a high level of anthropogenic transformation with a large share of fallows and shrubs. The biota of the studied territory consists of trivial, often synanthropic flora and fauna. They are represented by zonal

species common to this area. The vegetation of the studied area belongs to 11 classes, 12 orders, 14 unions, and  18  associations  according  to  the  Brown-Blanquet classification.  No  settlements,  species of flora, and fauna, which are included in the Red Book of Ukraine, the Green Book of Ukraine, and annexes to the resolutions of the Berne Convention, were found on the territory of the deposit. Coastal ecosystems with autotrophic blocks in the  form of  vegetation  classes Phragmiti- Magnocaricetea and Salicetea purpurea are affected by return water discharges. The discharge of reclaimed water from the Zhezheliv quarry stabilizes the existence of eutrophic coastal habitats with Phragmitetum australis and Typhetum angustifoliae vegetation associations. Also, by increasing the long-term wetting regime in the coastal areas, the condition of the Salici-Populetum association improves, which on the banks of rivers outside the zone of planned activity can acquire the status of a rare habitat (G1.11. Riverine Salix woodland). According to indicators of the dynamics of natural dynamics and the level  of  anthropogenic  transformation,  coastal  habitats  are  euhemerobic ecosystems at the stage of transition from the herbaceous to the tree-shrub stage of the autogenic succession. Raising the water level due to the discharge of Reclaimed waters will contribute to their restoration and return to a less transformed state.
Grado de adecuación a los requerimientos calóricos y proteicos en pacientes con dieta de textura modificada
Authors: Acerbo Florencia Yasmin , Lema Rocio , Lopez Mato Malena
Published: March 2023

Introducción: se estima que 8 % de la población a nivel mundial experimenta dificultad para consumir alimentos sólidos y líquidos. Los pacientes con dieta de textura modificada suelen tener una ingesta alimentaria variable.
Objetivos: determinar la asociación entre el porcentaje de adecuación descrito y los niveles de textura de la dieta.
Materiales y métodos: se evaluó la ingesta mediante un método de desperdicio de plato de 3 días. Los valores calóricos y proteicos se compararon con la ingesta dietética de referencia (IDR) según el estado nutricional. Se calculó el porcentaje de adecuación calórico y proteico. El análisis estadístico se realizó utilizando la prueba de Kruskal-Wallis para la comparación de medias según el nivel de IDDSI.
Resultados: la muestra se conformó por 52 pacientes hospitalizados mayores de 18 años con indicación de una dieta de textura modificada. La media del porcentaje de adecuación calórica fue de 72,31 %, 79,35 %, 83,9 %, para IDDSI 4, 5 y 6, respectivamente. La adecuación proteica fue de 71,89 %, 77,25 % y 80,75 %, para IDDSI 4, 5 y 6, respectivamente. No existen diferencias estadísticamente significativas en el grado de adecuación calórica y proteica en cada uno de los grupos según los niveles de IDDSI.
Conclusiones: el grado de adecuación calórica y proteica se encuentra por debajo de los estándares de comparación. Existe una tendencia a presentar un mayor porcentaje en la adecuación a los requerimientos calóricos y proteicos a medida que se incrementan los niveles de IDDSI, pero sin significancia estadística.
Empatía y Com-Pasión: la medicina que el mundo necesita
Authors: Pérez Cano Angélica María
Published: March 2023

Carta de la presidenta
Agent bankers and customer victimization in Ado City, Nigeria
Authors: Adeosun Oluwaseun Titi , Adeosun Omoniyi Alabi
Published: March 2023

Criminal victimization against agent bankers and their customers has recently been on the increase, and the multiplier effect is a major socio-economic problem that could cause a downturn in the economy. This study examines the exposure of agent bankers and their customers to criminal victimization in Ado city, Nigeria. Specifically, the study explores the forms of criminal victimization against agent bankers and their customers, examines the consequences of criminal victimization, looks into the cases of agent bankers and customer victimization, and determines the preventive measures adopted by agent bankers and their customers against victimization. Lifestyle-routine activity theory was deployed as the conceptual framework. An exploratory research design and snowball and purposive sampling with key informant and in-depth interviews were used to interview 12 victimized and non-victimized agent bankers and their customers. Interviews were conducted in Fayose market, King market, Bisi market, and Irona market. Findings reveal that agents’ bankers and their customers were being targeted by criminals who use non-violent tactics. The eagerness of the agent bankers to transact business brings a measure of carelessness to their business dealings. This carelessness and lack of security measures exposes them to motivated offenders. Victimization through fake alert, fraudulent transfer, withdrawal under false pretense, fraudulent alteration, intentional criminal patronage, fake identity, and urgent withdrawal under duress represent the themes found. It is imperative for agent bankers and their customers to set up security measures that could protect them against being victimized.
Ethical images and storytelling amidst differing expectations
Authors: Ogbu Oluchi G.
Published: March 2023

Non-governmental organizations (NGOs) and non-profit organizations (NPOs) seek creative ways to raise awareness about issues and connect with donors to raise the resources required to address the needs of the communities they work with. This paper highlights ethical challenges and lessons learned in using images and storytelling in the development sector. This article resulted from a capacity-building event on the ethical use of images from development projects. It draws from the event itself, which was organized by the Manitoba Council for International Cooperation (MCIC) in 2022, and from conversations leading up to and following the event between the author, guest speakers, and additional stakeholders.     The workshop was led by two representatives from MCIC member organizations. These two guest speakers shared experiences of using images and storytelling in their work in the Global South. Based on these conversations, this article highlights unequal power relations around the use of images from development projects, emphasizing organizations’ ethical challenges and how storytelling is (re)constructed amidst competing needs and expectations. The paper contributes to the ongoing discourse on ethical storytelling in fundraising and the need for decolonial storytelling.
Methodological approaches to assessing the quality of fish food products using sensory analysis: scientific review
Authors: Sytova M. V.
Published: March 2023

The purpose of the work: to propose express methodological approaches for establishing the quality and ensuring the safety of fish food products based on the use of sensory analysis, based on the results of a scientific review.

The methods that were used: a descriptive-analytical research method was used, a theoretical analysis of scientific, reference and methodological literature, as well as international and national regulatory documents in the field of organoleptics (sensorics) of food products was carried out.

The element of novelty is the systematization of information on methodological approaches to assessing the quality of fish food products using sensory analysis, followed by the development of a methodological manual for use in the fisheries industry.

Research results: determination of methodological system techniques for organoleptic (sensory) assessment of the quality of raw materials of aquatic origin and food products from it.

Practical significance: the possibility of using operational approaches to assessing the quality and safety of fish food products as express methods. The research materials will be used in the preparation of a methodological manual on quality control and safety of fish food products using sensory analysis for use in the fish processing industry and trade, for the implementation of control and supervisory measures, as well as for use for educational purposes.
“FUNCTIONAL OUTCOME OF BICOLUMNAR DISTAL END RADIUS FRACTURES TREATED BY VOLAR LOCKING PLATE”
Authors: K Harish. , Rakshith Ashoka , Sai Ranga Reddy P , M Daddimani Ravi , D Naveen
Published: March 2023

Introduction: Distal end radius fractures are one the foremost common injuries of the upper extremity.
Greatest prevalence was noticed elderly women who fall on their outstretched hand and young men
involved in impact injuries. This is a prospective study conducted in the Department of Orthoped Materials And Methods: ics,
Adichunchanagiri Institute of Medical Sciences, B.G.NAGARA after obtaining ethical clearance. This study consisted of 20
adult patients of either sex visiting outpatient department of the hospital/ casualty diagnosed to have distal end radius
fractures with the involvement of radial and intermediate columns. Patients satisfying inclusion criteria were included in the
study during the period from February 2021 to August 2022 In present stud Results: y 20 cases there were 12 males and 08
females with average age of presentation was 41.5 years, there was a predominance of right sided fractures when compared to
the left. Mean duration between admission and surgery was 3.2 days, the mean duration of complete radiological union was 6.6
weeks. We have achieved excellent results in 50% of cases, good results in 25%, fair results 25%, and no poor results.
Complications like Stitch abscess, stiffness, reduced range of motion, Persistent pain syndrome seen in 4 (20%) cases
Conclusion: This present study shows that volar locking plate is a better technique in view of shorter operative time, less
hardware, reduction in blood loss, less tendon irritation, lesser risk of neuromuscular injury. However this is a short term study
with small sample size, needs long term follow up to predict further outcome
Oil extraction, biochemical activities and in silico analysis for active compound valorization in Azardiricta indica seeds and production of microbial oil using Saccharomyces cerevisiae
Authors: Vaishnaw Chanchal , SVGK Kaladhar Dowluru
Published: March 2023

Neem oil is an excellent source of biofuel and medicinal levels that show good chemical components.
Fresh seeds of Azadirachta indica (neem seeds) were collected during summer season (April 2022) and
were dried in the sunlight for 24 hours. The dried seeds were kept in the seeds to oil machine and the oil was extracted by heat
press method. Around 45ml of the oil was extracted from 100 gm of seeds. The waste seed substrate of Azadirachta indica that
mix with yeast has shown the Microbial oil burn in glass plate. The extracted oil was tested for the biochemical activities to
understand about the chemical components (protein, carbohydrates, phenols, terpenoids, steroids, cholesterol, avonoids and
aminoacids) present in the oil. The seed oil and Petroleum ether mix with microbial oil (50:50) has shown little activity with
Candida, Enterococcus, Pseudomonas and Staphylococcus. No antimicrobial activity was observed with Ethanol dissolved
with microbial oil (50:50). Trypsin and proteinase K has shown protein degradation. The oil with proteinase has not shown
gelatin degradation indicates the oil mix with proteins making negative effect with gelatin degradation. QSAR (Quantitative
structure-activity relationship) properties shows no partial charges showing molecules as stable. The ligands and the receptor
has been selected in the present experimentation to understand about molecular docking process. Caffeic acid and
gallocatechin present in fresh seeds oil of Azadirachta indica (neem seeds oil) shown best activities with microbes.
MEASLES-RUBELLA VACCINE WITH ORAL ZINC VERSUS MEASLES-RUBELLA VACCINE MONOTHERAPY FOR PALMOPLANTAR WARTS
Authors: Shrivastava Pooja , P Manjunatha
Published: March 2023

Introduction Immunotherapy works by increasing cell mediated immunity against HPV. Some studies
have shown that combining immunomodulators with different MOA can result in a synergistic effect that
is slightly better than single therapy. To compare the efcacy of Intralesional measles-rubella (MR) Aim & Objectives: vaccine
with oral zinc VS IL MR vaccine monotherapy in treatment of palmoplantar warts In this hospital Materials and methods:
based, interventional study, 20 clinically diagnosed cases of palmoplantar warts were enrolled and randomly divided into 2
groups of 10 patients each. Group A received 0.5 ml/2 units of MR vaccine, injected into the largest wart. The dose was repeated
at 2-week intervals until complete clearance or maximum of 3 doses with oral zinc for one month. Group B received only 0.5ml/2
units of MR vaccine for the same period. Follow up was every 2 weeks for 3 months after last injection. Clinical improvement
assessed by physician's global assessment using visual analogue scale score. Statistical analysis done using SPSSversion21.
Results: In group A complete clearance in 60%, excellent response in 30%and good response in 10% , while in group B complete
clearance in 50%,excellent response in 30% and good response in 20%.The mean number of injection for complete clearance
3.6 in group A & 3.8 in group B. No recurrence in either group. Clinical improvement slightly better in group A than in group B.
Conclusion: In our study we found combination of two immunomodulators for the treatment of warts is slightly better than when
used individually.
A RARE CASE OF ACUTE HEMORRHAGIC CONJUNCTIVITIS IN A NEWBORN: A CASE REPORT
Authors: Thakur Umang , Gupta Vatika
Published: March 2023

The purpose of this publication is to highlight the clinical spectrum and management of acute
hemorrhagic conjunctivitis in minimal resource settings. Acute hemorrhagic conjunctivitis is a highly
contagious ocular infection characterized by lid edema, blood-stained discharge, pain, and subconjunctival hemorrhage. Most
common causes are infections with chlamydia trachomatis, coxsackie virus A-24, gonococcal infections