bluuebunny/crossref_metadata_2025 huggingface dataset:
Bilinear Bäcklund transformations, lump solutions and interaction solutions for (4+1)-dimensional variable-coefficient Fokas equation
Authors: Yang Huizhang , He Bin
Published: February 2023

After introducing an auxiliary variable, the (4+1)-dimensional variable-coefficient Fokas (4D vc-Fokas) equation is rewritten and its bilinear form is constructed by using the Bell polynomial. Based on the bilinear form, the bilinear Bäcklund transformation is obtained and some solitary wave solutions are derived. In addition, some new lump solutions and interaction solutions are given and the special solutions influenced by the parameter choice are analyzed.
Mathematics Subject Classification 35Q51 · 35Q53 · 68W30
Audio forgery detection and localization with super resolution spectrogram and keypoint based clustering approach
Authors: Ustubioglu Beste , Tahaoglu Gul , Ulutas Guzin , Ustubioglu Arda , Kilic Muhammed
Published: February 2023

Malicious individuals can modify speech recordings with advanced audio editing software to create forged audio. The most common forgery method, known as audio copy-move forgery, involves copying part of the audio to duplicate or delete a segment. Considering the fact that the speech recording is used as evidence in court, it is of great importance to detect whether the voice recordings are forged or not. To this end, we present an effective and robust method based on BRIEF and OPTICS to detect and locate audio copy-move forgeries. The proposed method uses super-resolution spectrogram images of the input audio to detect forged parts in suspicious audio recordings. For this purpose, key points and their feature descriptors are first extracted from the spectrogram image using the BRIEF method. The Ordering Points To Identify the Clustering Structure method (OPTICS) is used by the approach to match the corresponding descriptors. The proposed approach to eliminate false matches evaluates the correctness of the matches. The method also marks the corresponding forged segments in the audio file based on the location of the keypoints in these clusters. The performance results show that the proposed method has significantly high robustness to post-processing attacks such as noise addition, filtering, and especially compression, as reported in the literature.
Dual photo-enhanced interpenetrating network hydrogel with biophysical and biochemical signals for infected bone defect healing
Authors: Jian Guangyu , Li Dize , Ying Qiwei , Chen Xu , Zhai Qiming , Wang Si , Mei Li , Cannon Richard D. , Ji Ping , Wang Huanan , Chen Tao
Published: February 2023

The healing of infected bone defects (IBD) is a complex physiological process involving a series of spatially and temporally overlapping events, including pathogen clearance, immunological modulation, vascularization and osteogenesis. Based on the theory that bone healing is regulated by both biochemical and biophysical signals, in this study, we developed a copper doped bioglass (CuBGs)/methacryloyl-modified gelatin nanoparticle (MA-GNPs)/methacrylated silk fibroin (SilMA) hybrid hydrogel to promote IBD healing. This hybrid hydrogel demonstrated a dual-photocrosslinked interpenetrating network mechanism, wherein the photocrosslinked SilMA as the main network ensured structural integrity, and the photocrosslinked MA-GNPs colloidal network increased strength and dissipated loading forces. In an IBD model, the hydrogel exhibited excellent biophysical characteristics, such as adhesion, adaptation to irregular defect shapes, and in situ physical reinforcement. At the same time, by sequentially releasing biological biomimetic signals such as Cu2+, Ca2+, and Si2+ ions from CuBGs on demand, the hydrogel spatiotemporally coordinated antibacterial, immunomodulatory and bone remodeling events, efficiently removing infection and accelerating bone repair without the use of antibiotics or exogenous recombinant proteins. Therefore, the hybrid hydrogel can be used as a simple and effective method for the treatment of IBD.
Bibliometric and visual analysis of diabetes and pyroptosis from 2011 to 2022
Authors: Xiaodong Li , Xiaojuan Su , Mingchao Xu
Published: February 2023

Objective: To visualize and analyze the published literature on diabetes and pyroptosis based on a bibliometric approach, so as to provide a comprehensive picture of the hot research directions and dynamic progress in this field.
Methods: This study was based on the web of science core collection database to conduct a comprehensive search of the published literature in the field of diabetes and Pyroptosis from January 1985 to August 2022, including the published research literature in this field, as well as a visual analysis of the number of citations, year of publication, journal, author, research institution, country, and research topic.
Results: A total of 139 literature on research related to diabetes and cellular scorch from 2011 to 2022 were retrieved, with a total of 3009 citations and a maximum of 255 citations for a single article, which had a first authorSchmid-Burgk, JLThe first author of this article is from Germany; among 20 publishing countries, China leads with 100 articles; among 222 publishing institutions, Harbin Medical University leads with 18 articles and 184 citations; among 980 authors, Chen, X from China tops the list of high-impact authors with 5 articles and 29 citations; Among the 98 journals, "CELL DEATH DISEASE" ranked first in both volume and high impact journals with 4 articles and 29 citations; among 349 keywords, "pyroptosis" ranked first with a cumulative frequency of 65 times. The cluster analysis was divided into three categories, chronic complications of diabetes and pyroptosis (67 articles), diabetes and pyroptosis (60 articles), and diabetes combined with other diseases and pyroptosis (12 articles), and the number of articles related to diabetes and its chronic complications increased rapidly from 2019, among which, diabetic cardiomyopathy (27 articles) had the highest number of articles.
Conclusions: Based on a comprehensive analysis of published literature in the field of diabetes and pyroptosis from 2011-2022, this study achieved a visual analysis of studies with significant and outstanding contributions to the field, thus framing a picture showing the development and changes in the field. At the same time, this study provides research information and direction for clinicians and investigators to conduct diabetes and pyroptosis related research in the future.
Investigation of differences in susceptibility of Campylobacter jejuni strains to UV light-emitting diode (UV-LED) technology
Authors: Soro Arturo B. , Ekhlas Daniel , Marmion Maitiú , Scannell Amalia G. M. , Whyte Paul , Bolton Declan J. , Burgess Catherine M. , Tiwari Brijesh K.
Published: February 2023

Campylobacter jejuni remains a high priority in public health worldwide. Ultraviolet light emitting-diode technology (UV-LED) is currently being explored to reduce Campylobacter levels in foods. However, challenges such as differences in intra-species and intra-strain susceptibilities, effects of repeated UV-treatments on the bacterial genome and the potential to promote antimicrobial cross-protection or induce biofilm formation have arisen. We investigated the susceptibility of eight C. jejuni clinical and farm isolates to UV-LED exposure. UV light at 280 nm induced different inactivation kinetics among strains, of which three showed reductions greater than 1.62 log CFU/mL, while one strain was particularly resistant to UV light with a maximum reduction of 0.39 log CFU/mL. However, inactivation was reduced by 0.46–1.03 log CFU/mL in these three strains and increased to 1.20 log CFU/mL in the resistant isolate after two repeated-UV cycles. Genomic changes related to UV light exposure in were analysed using WGS. C. jejuni strains with altered phenotypic responses following UV exposure were also found to have changes in biofilm formation and susceptibility to ethanol and surface cleaners.
Harmonic maps on weighted foliations
Authors: Fu Xueshan , Qian Jinhua , Jung Seoung Dal
Published: February 2023

On foliations, there are two kinds of harmonic maps, that is, transversallyharmonic map and (F,F')-harmonic map which are equivalent when the foliation is minimal. In this paper, we study transversally ƒ-harmonic and (F,F')ƒ-harmonic maps on weightedfoliations. Moreover, we investigate the relations between transversal stress energy tensorsand tranversally ƒ-harmonic maps.
Cyclopeptide self-assembly simulated epidemic sequential and synchronous complexity
Authors: Xia Zhenfang , Wang Yong , Wang Qi
Published: February 2023

Epidemic growth curve was one of the epidemiological characteristics, which included sequential and synchronous and their complexity. Decoding the sequential and synchronous complexities of epidemic outbreaks will help guide the scientific response to the epidemic. Here, the complexities of epidemic sequential and synchronous were simulated from the perspective and method of cyclopeptide self-assembly, and the process of cyclopeptide self-assembly was observed by molecular fluorescence and morphological changes, reflecting the characteristics of the epidemic changes. The results showed that the cyclopeptide, namely cyclo(FWWYYF), self-assembly process took different forms under different concentrations and solvents. At lower concentrations, cyclopeptide molecules simulated the complexity of epidemic sequential and synchronous, while at higher concentrations, cyclopeptide molecules self-assembly also behaves as a non-sequential and non-synchronous composite multimodal model. These results indicated that the complexity of the epidemic outbreaks was not only the complexity of sequential and synchronous, but also the emergence of non-sequential and non-synchronous complex multimodal models. Molecular simulations elucidated why the global pandemic required global solidarity and synchronization.
The effects of intra-articular oxamate on anterior cruciate ligament transection-induced experimental osteoarthritic rats
Authors: Wen Zhi-Hong , Sung Chun-Sung , Lin Sung-Chun , Yao Zhi-Kang , Lai Yu-Cheng , Liu Yu-Wei , Wu Yu-Yan , Liu Hsin-Tzu , Chen Wu-Fu , Jean Yen-Hsuan
Published: February 2023

Background: Osteoarthritis (OA) is the most common form of joint disorder and arthritis worldwide. Joint pain and dysfunction are associated with this multifactorial disease characterized by the gradual degeneration of articular cartilage. The metabolic reprogramming of osteoarthritic chondrocytes to glycolysis instead of oxidative phosphorylation results in reduced ATP and lactate accumulation. When the glycolytic metabolite pyruvate is converted into lactate by lactate dehydrogenase A (LDHA), cartilage degeneration occurs. In the present study, we examined the chondroprotective effects of the LDHA inhibitor, oxamate on experimental OA rats.
Methods: Anterior cruciate ligament transection (ACLT)-induced ACLT-rats received an intraarticular (IA) injection of oxamate once a week for 5 weeks from the 10th to 14th after surgery. Animals were divided into four groups as follows: Sham, ACLT, ACLT + oxamate (0.25mg/kg), and ACLT + oxamate (2.5mg/kg). The results showed that an IA injection of oxamate significantly reduced weight-bearing defects and knee swelling in ACLT-rats.
Results: Histopathological analyses showed that oxamate caused significantly less cartilage degeneration than ACLT alone. Moreover, IA oxamate exerts hypertrophic effects in the chondrocyte of articular cartilage by inhibiting glucose-transporter 1, glucose-transporter 3, pyruvate kinase, LDHA, pyruvate dehydrogenase kinase 1, and pyruvate dehydrogenase kinase 2. Terminal deoxynucleotidyl transferase dUTP nick end labeling revealed that oxamate significantly reduced chondrocyte apoptosis in articular cartilage.
Conclusions: We propose that oxamate is beneficial for patients with OA and is associated with regulating glycolysis-related protein expression. In future clinical applications, our findings will provide new insights of LHDA inhibitor, oxamate into delaying strategies for OA progression.
N-methyl pyridinium tosylate (NMPyTs) and Ultrasound Promoted One-Pot Multicomponent Synthesis of Highly Functionalized of Tetrahydropyridine Derivatives
Authors: Sapkal Amol V. , Dinore Jaysing M. , Yelwande Ajeet A. , Palve Manoj P. , Madje Balaji R.
Published: February 2023

The N-methyl pyridinium tosylate (NMPyTs) ionic liquid is used as an efficient, homogeneous, and recyclable catalyst for the synthesis of tetrahydropyridine derivatives via one-pot multi-component condensation of aromatic aldehyde, anilines and β-ketoesters under ultrasonic irradiations and solvent-free conditions. This protocol was successfully pertinent to a wide range of structurally diverse aromatic aldehydes, substituted anilines, and β-ketoesters. The major characteristics of this technique include operational simplicity, short reaction times, mild reaction conditions, and high yield. Importantly, NMPyTs can undergo up to three recycle runs without any noticeable loss of catalytic activity.
A Spectral Learning Based Model to Evaluate Semantic Textual Similarity
Authors: Mehndiratta Akanksha , Asawa Krishna
Published: February 2023

Semantic Textual Similarity (STS) is a task in NLP that compares two sentences in a sentence-pair and scores the relationship between them using the degree of semantic equivalence. It has wide applicability in various fields. Consequently, the research around the task is constantly evolving. The demand for new as well as improved methods is endless. Numerous methods have been proposed that largely belong to either unsupervised or supervised learning approaches. The model proposed here is fairly simple and provides a fresh take on this classification problem using spectral learning. The model does not engage a large labeled corpus or lexical database like most STS supervised and unsupervised methods. Although, supervised STS methods achieve an accuracy that outperforms humans in some cases, but are often held back due to a lack of interpretation of the features instrumental in molding the decision-making process. The proposed model on the other hand generates features (latent knowledge) that are easy to ascertain and have a mathematical foundation. Given a sentence pair, the work focuses on finding latent states and variables from each sentence and performs classification by generating a similarity score. The latent variables are a result of projections learned by performing Canonical Correlation Analysis (CCA) amongst the sentence pair. To perform matching and determine the similarity score, Cosine similarity and Word Mover’s Distance (WMD) are employed. The performance of the proposed model does exhibit an improvement over various sophisticated supervised techniques such as LSTM and BiLSTM.
Mechanism of Zn2+ regulating cellulase production in Trichoderma reesei Rut-C30
Authors: Li Ni , Li Jing , Chen Yumeng , Shen Yaling , Wang Wei
Published: February 2023

Background
Trichoderma reesei Rut-C30 is a hypercellulolytic mutant strain that degrades abundant sources of lignocellulosic plant biomass into renewable biofuels. Zn2+ is an activator of enzymes in almost all organisms; however, its effect on cellulase activity has not been reported in T. reesei.
Results
Although high concentrations of Zn2+ severely hampered the extension of T. reesei mycelia, adding 1–4 mM Zn2+ improved cellulase production in T. reesei high-yielding cellulase-producing strain Rut-C30. The expression levels of the major cellulase genes and two critical transcription activators (xyr1 and ace3) increased significantly on Zn2+ addition. Transcriptome analysis revealed that the mRNA level of plc-e encoding phospholipase C, which is involved in the calcium signaling pathway, was enhanced by Zn2+ addition. The disruption of plc-e abolished the cellulase-positive influence of Zn2+ in the early phase, indicating that plc-e is involved in Zn2+-induced cellulase production; furthermore, supplementation with LaCl3 (a plasma membrane Ca2+ channel blocker) and deletion of crz1 (calcineurin-responsive zinc finger transcription factor 1) demonstrated that calcium signaling is partly involved in this process. Moreover, we identified the zinc-responsive transcription factor zafA; the transcriptional level of zafA decreased significantly with Zn2+ stress, and its deletion indicated that zafA mainly mediates Zn2+-induced cellulase production.
Conclusions
For the first time, we have demonstrated that Zn2+ was toxic to T. reesei and it remarkably promoted cellulase production. This positive influence of Zn2+ was facilitated by the gene plc-e and the transcription factor zafA. These findings provide insights into the role of Zn2+ in T. reesei and a mechanistic study of signal transduction in cellulase synthesis.
Skincare Potential of a Sustainable Postbiotic Extract Produced Through Sugarcane Straw Fermentation by Saccharomyces Cerevisiae
Authors: Duarte Marco , Carvalho Maria João , Carvalho Nelson Mota , Silva João Azevedo , Mendes Adélia , Ribeiro Inês Pinto , Fernandes João Carlos , Oliveira Ana Lucia , Oliveira Carla , Pintado Manuela , Amaro Ana , Madureira Ana Raquel
Published: February 2023

Postbiotics, a new class of molecules derived from microorganism’s metabolism, are defined as a “preparation of inanimate microorganisms and/or their components that confers a health benefit on the host”. They can be produced by fermentation, using culture media with glucose as the carbon source, and lactic acid bacteria of the genusLactobacillus, and/or yeast, mainlySaccharomyces cerevisiaeas fermentative microorganisms. Postbiotics comprise different metabolites, and have important biological properties (antioxidant, anti-inflammatory, etc), which is why their use in cosmetics should be considered. During this work, the production of postbiotics was carried out by fermentation with sugarcane straw, as a source of carbon and other active compounds, and as a more sustainable and promising process to obtain more bioactive extracts at the end. For this, its saccharification process was carried out with cellulase at 55 ºC for 24 h. Fermentation was performed sequentially after saccharification at 30 ºC, for 72h, usingS. cerevisiae. The cells-free extract was characterized regarding its composition, antioxidant activity, and skincare potential. Its use was safe at concentrations below ~ 20 mg.mL− 1for keratinocytes and ~ 7.5 mg.mL− 1for fibroblasts. It showed antioxidant activity, with ABTS IC50of 1.88 mg.mL− 1, and inhibited elastase and tyrosinase activities by 83.4% and 42.4%, respectively, at the maximum concentration tested (20 mg.mL− 1). In addition, it promoted the production of cytokeratin 14, and demonstrated anti-inflammatory activity at a concentration of 10 mg.mL− 1. Finally, in the skin microbiota of human volunteers, the extract inhibited theCutibacterium acnesbacterium and theMalasseziafungal genus. In short, postbiotics were successfully produced using straw as substrate, and as source of carbon and phenolic compounds. These postbiotics showed bioactive properties that potentiate their use in the development of cosmetic and skincare products, such as the treatment of acne or other skin diseases, due to their anti-inflammatory and inhibitory effect on the bacteria responsible for acne, as well as on potentially colonizing fungi.
Time pattern variation of alien plant introductions in an insular biodiversity hotspot: The Balearic Islands as a case study for the Mediterranean region
Authors: Cerrato Marcello Dante , Cortés-Fernández Iván , Ribas-Serra Arnau , Mir-Rosselló Pere Miquel , Ametller Carles Cardona , Gil-Vives Lorenzo
Published: February 2023

Allochthonous plant species are considered among the main environmental issues worldwide, being especially accused in the Mediterranean basin. The present study aims to update Balearic Alien Flora and discuss its time and spatial variation and invasiveness. Information regarding allochthonous plant records of the Balearic Islands were gathered and analysed based on published checklists and online databases. For each species several general traits were assigned based on previous references to characterise the alien Balearic Flora. Records of allochthonous species between 1827–2023 indicate that Alien Balearic Flora is composed of 602 taxa recorded unevenly among islands with lower records in smaller islands. Alien flora is mainly composed of therophytes and phanerophytes being held mainly in human related habitats. Introduction pathway is mainly ornamental, with over 50% of taxa entering through gardening and horticultural practices. Main biogeographical origins are American, Mediterranean, Euroasiatic and Cape origins. Invasive status of Balearic alien flora shows that 46% of all taxa can be regarded as casual, while 36% are naturalised, and 18% can be considered invasive, being the latter increased in smaller islands. Time variations trends starting mainly in the 70s and predictive models show that alien species increase exponentially, being the most represented taxa from synanthropic habitats, introduced as ornamentals, lianes, phanerophytes and therophytes from Cactaceae, Asteraceae and Leguminosae families. The results of the present study can serve as a model to facilitate the scientifically informed decision making and management of plant invasions both in the Balearic Islands and other continental insular systems and Mediterranean regions.
Prescribing pattern and associated factors in community pharmacies: A cross-sectional study using AWaRe classification and WHO antibiotic prescribing indicators at Dire Dawa, Ethiopia
Authors: Dereje Beyene , Workneh Alemseged , Megersa Alemayehu , Yibabie Shegaye
Published: February 2023

Background: Antibiotics are more likely to trigger the development of antimicrobial resistance than other medications. Thus, they need to be prescribed, dispensed, and administered with greater caution. Timely evidence on medicine use, prescribing patterns, and the factors affecting the prescribing of an antibiotic would help decision-makers draft guidelines that would enable a more rational use of medicines.
Methods: Prospective and cross-sectional study was conducted in seven community pharmacies in Dire Dawa to assess current prescribing practices, including antibiotic use and associated factors. Using stratified random sampling techniques, 1200 encounters were reviewed between October 1 and October 31, 2022 and SPSS version 27 was used for descriptive statistics and logistic regression.
Results: The average medications per prescription was 1.96 and antibiotics were included in 47.83% of encounters while 43.03% were prescribed from Watch group. In 13.5% of the encounters, injections were administered. In multivariate models, patient age, gender, and the number of medications prescribed were all substantially related to the prescription of antibiotics. Antibiotics were about 2.5 times more likely to be prescribed to patients under the age of 18 than to subjects 65 and older (AOR: 2.51, 95% CI: 1.62-2.52; P <.001). Men were also more likely than women to receive an antibiotic prescription (AOR: 1.74, 95%CI: 1.18–2.33; P = 0.011). Subjects who those who received more than two drugs were 2.96 times more likely to receive an antibiotic (AOR: 2.96, 95%CI: 1.77–6.55; P = 0.003). The probabilities of prescribing antibiotics increased by 2.57 units for every unit increase in the number of medications (COR: 2.57; 95%CI: 2.16-3.47; P = 0.002).
Conclusions: According to this study, the amount of prescriptions with antibiotics at community pharmacies much higher than the WHO standard (20–26.2%). Additionally, 13.5% of encounters involved an injection, which is comparable to the World Health Organization standard of 13.4-24.1%. The prescribing of antibiotics was significantly correlated with the patient's age, gender, and number of medications.
A mathematical useful proof about the cardinality and the intersection of P problems and NP-Complete problems
Authors: Louiz Akram
Published: February 2023

Thanks to my short studies about informatics, I present to you this mathematical proof that deals with the sets of P problems, NP-Complete problems and NP-Hard problems in order to prove new formulas about the cardinality of each group of problems and about the intersection of each one of these sets. This work ends with a strange contradiction about the cardinality of the intersection of the sets of P problems and NP-Complete problems. And thus, some probable causes about the followed method are proposed in order to inform the readers and invite them to reply by there own logical remarks.
Theoretical and Methodological Aspects of Innovative-Industrial Cluster Development in the Era of Digitalization
Authors: Safarov Ganimat , Sadiqova Sabina , Urazayeva Milyanat , Abbasova Narmina
Published: February 2023

This article summarizes the arguments and counterarguments within the scientific debate on the identification of the main theoretical and practical principles of the functioning of innovative-industrial clusters in different countries, as well as the formalization of the impact of digitalization on their activities. The article summarizes scientific approaches to determining the main characteristics and features of the functioning of innovation-industrial clusters. In order to substantiate the theoretical background of the relationship between innovation-industrial clusters’ performance and digitalization processes, a bibliometric analysis of the main Scopus publications in this direction is carried out using the VOSviewer toolkit. That made it possible to identify the main essential and contextual clusters of scientific research on relevant topics to characterize the evolutionary patterns of their changes during the analysis period. In order to determine the empirical causality of the impact of digitalization on innovative and industrial development, an integral indicator of innovative and industrial development is developed. The Index considers the measurement parameters and regional features of industrial, entrepreneurial, and innovative development. Indicators were integrated using the principal components analysis and additive convolution. The study modelled the influence proxies of the digital economy on the integrated indicator of innovative and industrial development using panel data regression modelling in the Stata 14.2/SE software. In the paper, it is also identified those determinants of the digital development of the state that depends to the greatest extent on the volatility of the innovative and industrial development of the country using one-factor regression models. The study is conducted for the country sample with 10 countries, including Azerbaijan, Estonia, Georgia, Kazakhstan, Kyrgyzstan, Latvia, Lithuania, Poland, Romania, and Ukraine. The time horizon of the study covers the period 2009-2021 (or the latest available period). The research results can be useful to scientists, state authorities, and local governments.
Innovations in Energy Efficiency Management: Role of Public Governance
Authors: Ziabina Yevheniia , Navickas Valentinas
Published: February 2023

The article summarizes the arguments and counter-arguments within the scientific debate on the influence of state administration on innovations in energy efficiency management of the national economy. The main goal of the conducted research is to form and prove a hypothesis regarding the effectiveness of the methodological toolkit for assessing the impact of the level of government efficiency on the divergent energy efficiency subindex of the national economy. The systematization of literary sources and approaches to solving the problem of the role of state administration in the context of the formation of innovations in energy efficiency management proved that active discussions are currently underway on this topic. The urgency of solving this scientific problem is to develop an effective mechanism for finding additional determinants of influence on the level of energy efficiency for the further possibility of harmonizing domestic and European energy policies. The study of the role of state management of the innovative component of energy efficiency development in the article is carried out in the following logical sequence: at the first stage, the initial data array was formed, which was checked for multicollinearity (Pearson’s correlation coefficient) and normality of distribution (graphic quantile method of comparing two probability distributions) using statistical analysis tools at the second and third stages; at the fourth stage, a quantile regression OLS model was built, which allows taking into account the heterogeneity of the studied factors. Methods of bibliometric and comparative analysis, correlational and quantile methods became the methodological tools of the conducted research, the years from 2000 to 2020 were chosen as the research period. Ukraine and the EU countries (27) were chosen as the object of the study, because they allow us to compare the level of energy efficiency of countries and their positions in the world ranking of the quality of public administration. The article presents the results of an empirical analysis and found that for Ukraine, the diffusion of green innovations leads to a slight increase in the level of energy efficiency of the national economy by 0.7%, while for the countries of the European Union – by an average of 3%. The experience of the countries of the European Union shows that the multiplier effect in increasing the energy efficiency of the national economy is provided by the growth of green innovations and the activation of the green investment market. Increasing the efficiency of public administration to the level of reference countries will allow to increase the divergent energy efficiency sub-index for Ukraine by 16.1% for the rule of law, 18.9% for the government’s ability to openly implement policies and regulatory measures, and 10.7% for corruption control. The results of the conducted research may be useful for further research in the field of energy efficiency of the national economy.
ANALISIS MAJAS ELIPSIS DALAM AL-QUR’AN DAN FRASA BAHASA ARAB
Authors: Ulin Nuha Muhammad Afthon
Published: February 2023

Ellipsis is one of the phenomena of language structure that occurs to display a meaning by not mentioning all the pronunciation elements. The phenomenon of ellipsis occurs in many languages, including Arabic. In Arabic, even an ellipsis seems to contain several unique patterns, among others: there is a mandatory ellipsis, some are allowed to have ellipsis, and some are not allowed to have ellipsis. Departing from this problem, the writer considers it necessary to express thoughts about ellipsis in Arabic and will begin with Arabic phrases. By using the library research method, which is then processed using an inductive or deductive approach, it is hoped that it can produce conclusions about various ellipsis patterns in the Qur'an and Arabic phrases. In this study, it was also found that ellipsis on the Qur'an and Arabic phrases, in general, can be done if it does not cause ambiguity in meaning. Another value of the ellipsis is for the efficiency of word use, and more focus on the intended meaning.
PLACE DU BILAN DHEMOSTASE EN PREOPERATOIRE : ETUDE DES PRATIQUES DE LHOPITAL UNIVERSITAIRE JRA ANTANANARIVO MADAGASCAR
Authors:   UPFR Hematologie CHU-JRA Antananarivo, Madagascar., Zolalaina Huberthine Rakotoarivelo , Tsiriniaina Ramavoson ,   Laboratoire du CHU Morafeno Toamasina, Madagascar., Bronislaw Tchesterico Dodoson ,   Laboratoire de Biologie Medicale CHU Andrainjato Fianarantsoa, Madagascar., Andriamiadana Luc Rakotovao ,   Laboratoire de Biologie Medicale CHU Joseph RasetaBefelatanana Antananarivo, Madagascar., Andriamahatratsoa Tahirimalala Rabenandrianina ,   Centre Regional de Transfusion Sanguine CHU PzaGaAndrova Mahajanga, Madagascar., Alson Aimee Olivat Rakoto ,   UPFR Hematologie CHU-JRA Antananarivo, Madagascar., Andry Rasamindrakotroka ,   Laboratoire de Rechercheet de Formations en Biologie Medicale Faravohitra Antananarivo, Madagascar.
Published: February 2023

Introduction: Le bilan dhemostase est devenu une routine dans certains pays pour evaluer le risque hemorragique peri-operatoire. Lobjectif principal de cette etude etait devaluer les resultats des bilans dhemostase preoperatoires effectues au laboratoire dhematologie. Methodes et resultats:Une etude transversale retrospective descriptive et analytique a ete menee a lunite dhematologie du CHU Joseph Ravoahangy Andrianavalona pendant trois mois. Elle concernait des patients ayant realise des bilans dhemostase preoperatoires durant cette periode. Parmi 269 patients, 98 patients avaient des troubles de la coagulation preoperatoire. Le taux de prothrombine (TP) bas predominait dans 38,1% des cas, dont 68,9% etaient isoles et 31,1% etaient associes a lallongement de temps de cephaline active (TCA). La thrombocytose a ete retrouvee dans 37,3% des cas, la thrombocytopenie dans 15,3%. Lallongement du TCA a ete retrouve dans 9,3% des cas. Conclusion:Lesbilans dhemostase preoperatoire standards ne peuvent a eux seuls predire le risque de saignement. Leur prescription doit etre selective en fonction des antecedents et de la clinique. La recherche de letiologie des anomalies est importante pour ameliorer la prise en charge peri et post-operatoire.
INGUINAL HERNIA IN FEMALE CHILDREN - A CASE SERIES OF 19 PATIENTS
Authors:   MS,FICS, FACS, FIAGES, Department of Surgery Skims Medical College, Bemina Srinagar Jammu and Kashmir., Ul Bari Shams , Nabi Naveed ,   MBBS, MS, Department of Surgery Skims Medical College, Bemina Srinagar, Jammu and Kashmir.
Published: February 2023

BackgroundInguinal hernia is quite uncommon in females as compared to males and may pose a diagnostic as well as a surgical challenge to the surgeons. Thorough knowledge of the anatomy of the region and the variable nature of contents is essential to prevent any complications. The cumulative incidence of inguinal hernia from birth to 15 years of age has been reported as 6.62% in males and 0.74% in females. Aims and objectivesThe aim of the study was to study the clinical profile and management of inguinal hernia in female children. Material and methodsThestudy,Inguinal Hernia in Female Children â€“ A case series of 19 patients was conducted prospectively in the department of Surgery at Sheri-Kashmir Institute of Medical Sciences Medical College Srinagar from March 2017 to February 2022. All the female children in the age group of 1 to 14 years who presented with clinical or Sonographic evidence of inguinal hernia were included in the study. Results and observations Total number of patients studied was nineteen. All the study patients had indirect inguinal hernia, with right sided hernia in 8 (42.10%), left sided hernia in 10 (52.25%) patients and bilateral hernia in one patient(5.26%).At the time of surgery, indirect sac alone was found in 50% patients, indirect sac containing omentum was seen in 18.75% patients and a sac containing small bowel was seen in 25% patients.One patient had a sliding hernia containing ovary and fallopian tube. All the patients underwent herniotomy under general anesthesia. Conclusion Thorough knowledge of female inguinal anatomy is essential before attempting any surgical intervention for inguinal hernia. The possibility of a sliding inguinal hernia with uterus, fallopian tube and ovaries should be considered and may present as an incarcerated inguinal hernia in females.Herniotomy is the surgical procedure of choice in all patients.
DOMESTIC VIOLENCE DURING FIRST AND SECOND WAVE OF COVID IN SRINAGAR
Authors: Aalia Dkhar Sabira , Quansar Ruqia , Salim Khan S.M.
Published: February 2023

Violence against women and girls is a human rights violation. Domestic abuse, also called domestic violence or intimate partner violence, can be defined as a pattern of behaviour in any relationship that is used to gain or maintain power and control over an intimate partner. Domestic violence affects people of all socioeconomic backgrounds and education levels. Study design: cross-sectional study design. Research tool: semi structured pre-tested questionnaire. Sample size was calculated based on recent study on domestic violence which showed an increase of 5% during pandemic. Sampling technique was convenient purposive sampling. We had 92 participants. Out of which 42 were married women. Around 31 were of the age group 31-40. About 16 out of 92 said they have experienced domestic violence. Out of 16, 6 had experienced abuse during Covid while 10 said it started before Covid. All of the 16 women had confided about this to someone. 10 of them had never seeked for help, 6 who had seeked for help had received some kind of assistance.
THE IMPLEMENTATION OF PRUDENTIAL BANKING PRINCIPLES AND THE VALIDITY OF POWEROF ATTORNEY TO CHARGE MORTGAGE RIGHTSMADE BASED ON A SALE AND PURCHASE PRELIMINARY AGREEMENT AND POWER DEED OF SALE
Authors:   Master Student, Faculty of Law, Jenderal Soedirman University, Indonesia., Indah Ahasani Amalia , Lisiani Prihatinah Tri ,   Associate Professor, Faculty of Law, Jenderal Soedirman University, Indonesia., a Sulistyandari ,   Senior Lecturer, Faculty of Law,Jenderal Soedirman University, Indonesia., Wahyu Handayani Sri ,   Senior Lecturer, Faculty of Law, Jenderal Soedirman University, Indonesia.
Published: February 2023

Banks carry out their business it must apply the principle of prudential in granting credit. In the High Court Decision Number 23 / Pdt / 2017 / PT YYK stated that Bank Perkreditan Rakyat Gunungkidul had violated the prudential banking principle because of the credit disbursement too fast. In addition, making a Power of Attorney to Charge of Mortgage Rights based on a Sale and Purchase Preliminary Agreement followed by a Power Deed of Sale is against the law. The research method is normativejuridica,using secondary data from libraryresearch. The application of the prudential principle of banks in extending credit is by analyzing the 5 Cs principles, namely Character, Capacity, Capital, Collateral, and Condition of Economy. So that credit disbursement that is too fast does not violate of the prudential principle. Power of Attorney to Charge of Mortgage Right whose object is still based on a Sale and Purchase Preliminary Agreement and Power Deed of Sale, based on Article 1334 paragraph (1) of the Civil Code, which relates to goods that will exist. However, after the Power of Attorney to Charge of Mortgage Rights is made, a transfer of rights must carry out by following Article 37 paragraph (1) of Government Regulation Number 24 of 1997 concerning Land Registration Juncto Article 2 paragraph (2) Government Regulation 37 of 1998 as amended by Government Regulation Number 24 of 2016 concerning Regulations for the Position Land Deed Officials so that a deed of granting mortgage rights can make.
STUDY OF PROGNOSIS OF PATIENTS WITH PERITONITIS USING MANNHEIM PERITONITIS INDEX SCORING SYSTEM
Authors:   Assistant Professor ACSR. Govt. General Hospital & Medical College, Nellore, AP, India., Prasad M.S Gen. Surgery K. , Chirimala M.S Gen. Surgery Y. ,   Assistant Professor ACSR. Govt. General Hospital & Medical College, Nellore, AP, India., Pratap Kumar M.S Gen. Surgery A. ,   AssistantProfessor ACSR. Govt. General Hospital & Medical College, Nellore, AP, India.
Published: February 2023

Discussions of the treatment of peritonitis and the evaluation of different therapeutic approaches are hampered by the lack of precise classification (ability).1The advantages of various scoring systems used in other studies like Glasgow coma scale, TNM Staging and APACHE scores in the evaluation of the pathophysiology and in comparing the efficacy of the treatment made one search for a similar scoring system in evaluation of peritonitis.ie., Mannheim peritonitis index.
NOTARY LIABILITY FOR CLIENT DOCUMENTS PROVEN TO BE FAKE DUE TO CARELESSNESS
Authors:   Master Student, Faculty of Law, Jenderal Soedirman University, Indonesia., Larasati Intan , a Budiyono ,   Senior Lecturer, Faculty of Law, Jenderal Soedirman University, Indonesia., Wasi Bintoro Rahadi ,   Senior Lecturer, Faculty of Law, Jenderal Soedirman University, Indonesia., Wahyu Handayani Sri ,   Senior Lecturer, Faculty of Law, Jenderal Soedirman University, Indonesia.
Published: February 2023

Notary is required to be responsible for the deed he has made. Sometimes, deeds made before a notary contain fake documents, fraud and even untruth and are often subject to articles 263, 264, 266 in conjunction with Article 55 of the Criminal Code. The task of a notary is to record data and information provided by clients in accordance with the obligations of a notary in Law Number 2 of 2014 concerning the office of a notary, article 16, article 1 letter (f). The Notary Office Law does not specifically regulate legal protection for notaries in the examination process regarding forgery of client documents. For this reason, the criminal liability of a notary for a deed made on the basis of a forged document as a result of not applying the precautionary principle needs to be studied and analyzed. This can be started by ensuring and checking the formal correctness of the client if it is considered lacking. Supposedly, notaries seek material truth in order to achieve the goal of the precautionary principle in knowing clients and minimizing the possibility of problems occurring in the future.
IMPETIGO HERPETIFORMIS IN A CASE REPORTPRESENTATION OF A RARE ENTITY
Authors:   Gynecology and Obstetrics Department at Mohammed VI University Hospital of Oujda, Morocco., STIMOU Sanae , TAHERI Hafsa ,   Gynecology and Obstetrics Department at Mohammed VI University Hospital of Oujda, Morocco., SAADI Hanane ,   Gynecology and Obstetrics Department at Mohammed VI University Hospital of Oujda, Morocco., MIMOUNI Ahmed ,   Gynecology and Obstetrics Department at Mohammed VI University Hospital of Oujda, Morocco.
Published: February 2023

Impetigo herpetiformis (IH) is a very rare and specific pustular dermatosis of pregnancy that can be life-threatening for both mother and child. This entity is currently considered as a variant of pustular psoriasis. We report an observation of a 35-year-old female patient who presented with extensive erythematous-pustular plaques for which the diagnosis of impetigo herpetiformiswas made clinically and histologically. The lesions appeared in the third trimester of pregnancy without fetal or maternal impact. The treatment was prednisone, vitamin D supplementation and a macrolide for 10 days.
PSYCHOTRAUMA AND CLINICALPOLYMORPHISM : CASE REPORT
Authors:   Hopital Universitaire Psychiatrique Arr-Azi ,CHU Ibn Sina Rabat., Zaki Amal ,   Faculte De Medecine Et De Pharmacie De Rabat. Universite Mohammed V, Rabat., Sabir Maria ,   Professeur En Psychiatrie., El Omari Fatima ,   Professeur En Psychiatrie.
Published: February 2023

The clinical description of psychotrauma has undergone a huge change since the advent of the new versions of international classifications, in particular the DSM 5, which through basic clinical criteria (reliving/hypervigilance/avoidance), helps the clinician to make the diagnosis of post-traumatic stress disorder (PTSD). However, psychotrauma presents transonographic and transcultural characteristics, as it can take on different clinical pictures, essentially a psychotic picture, which can mislead the diagnosis and in this case the therapeutic management. Through a clinical vignette rich in clinical polymorphism, we will expose the different difficultes encountered, highlighting the need for an approach based on a multidimensional approach criteriological perhaps, but psychopathological and phenomenological certainly. Therefore, it is important that the clinician takes into consideration the cultural, social and biological dimension in order to guarantee a good management both with medication and psychotherapy.
Resilience and vulnerability of a person in a community in the context of military events
Authors: Kupenko Olena , Kostenko Andriana , Kalchenko Larysa , Pehota Olena , Kubatko Oleksandr
Published: February 2023

A full-scale Russian invasion in Ukraine changes people’s behavior and determines the current person’s resilience/vulnerability in society. This paper aims to estimate individual resilience/vulnerability and its factors in the community during wartime. It used the online survey method based on Google Forms and online focus-group interviews during May-August 2022 at four territorial communities in Kyiv, Lviv, Mykolaiv, and Sumy regions, which geographically represent the whole of Ukraine. A randomly selected 468 respondents were interviewed, including 139 internally displaced persons and refugees and 329 who did not consider themselves in any vulnerable category. The survey shows that according to the “Well-being and baseline status” factor, 66.3% of respondents confirmed an increase in their activity in response to the war.Along with a high level of trust in their family during wartime, indicators of social atomization (broken social ties, isolation of people from each other) are high. Thus, 37.4% of respondents noted that they rely only on themselves and solve their problems independently, without anyone’s help. Using the Connor-Davidson Resilience Scale, it was found that the social resilience of the Ukrainian population is mainly based on individual resilience rather than on the resilience of mechanisms. For almost 50% of the respondents, there are manifestations of atomized sustainability and vulnerability, which increase the likelihood of post-traumatic stress disorder. Therefore, the control over disaster management processes should be based not only on data monitoring but also on training and innovativeness to increase social resilience. AcknowledgmentThis study was funded by a grant “Restructuring of the national economy in the direction of digital transformations for sustainable development” (No. 0122U001232).
GuideLiner Balloon Assisted Tracking for deep cathether intubation to address challenging distal coronary lesions
Authors: Thiele John M , Mathbout Mohammad , Fernandes Valerian
Published: February 2023

As the medical treatment and survivability of coronary artery disease improve, patients requiring catheter-based coronary intervention present with increasingly challenging coronary anatomy. Navigating complicated coronary anatomy requires a diverse armamentarium of techniques to reach distal target lesions. Here, we discuss a case in which we used GuideLiner Balloon Assisted Tracking, a technique formerly used to achieve difficult radial access, to facilitate delivery of a drug-eluting stent to a challenging coronary target.
CERCA (Cascading Effects in Risk Consequences Assessment): An operational tool for geo-hydrological scenario risk assessment and cascading effects evaluation
Authors: Biondi Daniela , Scarcella Graziella Emanuela , Versace Pasquale
Published: February 2023

Building multiple, complex risk scenarios is a priority for the improvement of the effectiveness of early warning systems and technical countermeasure designs to detect phenomena associated with severe weather events, such as floods and landslides. This study presents CERCA (Cascading Effects in Risk Consequences Assessment), a methodology for the characterisation of event scenarios that is consistent with the current Italian Civil Protection Guidelines on the national warning system for weather-related geo-hydrological and hydraulic risks. The aim is to propose a simple, effective, multi-scale operational tool that can be adapted to multiple purposes. CERCA is structured as a tool for a typical ‘scenario analysis’ in a multi-hazard context through the qualitative assessment of cascading effects and consequences for different categories of elements at risk, particularly in terms of human losses. The framework is assessed on a case study concerning a local event in Rossano (Calabria, Italy) and on a number of damaging events that occurred in Italy during the period 2004–2021. The proposed approach can be effective in processing post-disaster information, monitoring the real-time evolution of critical situations, creating priority lists for decision-making, and providing general dependency matrices to be used for ‘ex-ante’ definitions of scenarios.