bluuebunny/crossref_metadata_2025 huggingface dataset:
Facilitators and barriers in the rehabilitation process described by persons with spinal cord injury: a deductive-inductive analysis from Finnish Spinal Cord Injury Study
Authors: Tallqvist Susanna , Eskola Kaarina , Täckman Anni , Kauppila Anna-Maija , Koskinen Eerika , Anttila Heidi , Rajavaara Marketta , Arokoski Jari , Hiekkala Sinikka
Published: October 2022

Background
A spinal cord injury (SCI) has multiple effects on the persons’ life, and can lead to impairments in activities, social participation, and environmental factors. Rehabilitation is important for regaining functioning and new skills. The aim of the study wasto determine the factors that people with SCI perceived as promoting and facilitating their rehabilitation, and what they found to be challenges and possible barriers.
Methods
This study was part of a larger, mixed method Finnish Spinal Cord Injury study (FinSCI). The current study had a qualitative approach and used a deductive-inductive content analysis. The deductive approach was guided by a theory of six phases of a rehabilitation process by Autti-Rämö, followed by an inductive analysis to describe in-depth the perceptions of persons with SCI in each phase of the rehabilitation process. We collected the data by interviews from 45 persons representing participants from FinSCI study and used a structured interview guide.
Results
We found 28 facilitators and 19 barriers in the rehabilitation process. The majority of the facilitators and barriers were related to the phase of rehabilitation planning. There were more barriers than facilitators at the beginning of the rehabilitation process in applying for and accessing treatment or rehabilitation, and during the implementation of rehabilitation. As for the facilitators that progressed the rehabilitation process, some of them included: successful or realized, planned treatments, rehabilitation events, clear goals, multidisciplinary teamwork, support, and monitoring various changing situations, and rehabilitating one’s own capability and activity. The barriers were: delays, challenges and deficiencies in the planning and implementation of their treatment or rehabilitation, the lack of different rehabilitation professionals’ skills and resources, and different patients’ personal factors, which made the progress of the rehabilitation process cumbersome.
Conclusions
We identified that communication and interaction were common denominators for the facilitators and barriers. Good communication and interaction among rehabilitation professionals and rehabilitees promoted the occurrence and repetition of facilitating factors during different phases of the rehabilitation process. Good care and good rehabilitation practice for people with SCI were the result of multidisciplinary teamwork, in which a person with SCI was an active member.
Causes of Death in Patients with a History of Severe Anorexia Nervosa
Authors: Westmoreland Patricia , Duffy Alan , Rienecke Renee , Grange Daniel Le , Joiner Thomas , Manwaring Jamie , Watters Ashlie , Mehler Philip
Published: October 2022

Objective:
This study reports causes of death for a cohort of 35 patients with severe anorexia nervosa (AN), who were treated between 2012 and 2020, and descriptive information on their medical and psychological comorbidities is provided.
Methods:
Three hundred and seventy patient names were submitted to the National Death Index (NDI). The NDI reviewed whether a death certificate matching each patient’s identifying information existed, and if it existed, specific causes of death were noted. The original group of 370 patients consisted of 229 individuals who had been treated voluntarily and 141 who had been treated involuntarily.
Results:
Thirty-five patients from the 370 (0.09%) submitted to the NDI were confirmed deceased. Most (83%) were female with an average age of 38.5 years (SD:12.7) and average body mass index (BMI) of 12.8 kg/m² (SD:2.4). The total number of patients with AN listed as a cause of death was 24 (69%). Two patients died as a result of suicide. Twenty-eight (80%) of the patients had a specific medical disease listed as a cause of death, with the most frequent being cardiovascular, metabolic, or gastrointestinal.
Conclusions:
AN is associated with a substantial risk of death from many medical causes. However, two (5.7%) of our sample died by suicide, a rate considerably lower than previously reported.
Impact of Sumadhur intervention on fertility and family planning decision-making norms: A mixed methods study
Authors: Mitchell Ashley , Puri Mahesh , Dahal Minakshi , Cornell Alia , Upadhyay Ushma , Diamond-Smith Nadia
Published: October 2022

Background

Mindful of social norms shaping health among women pressured to prove early fertility in Nepal, a bi-national research team developed and piloted a 4-month intervention engaging household triads (newly married women, their husbands, and mothers-in-law) toward advancing gender equity, personal agency, and reproductive health. This study evaluates the impact on family planning and fertility decision-making.

Methods

In 2021, Sumadhur was piloted in six villages with 30 household triads (90 participants). Pre/post surveys of all participants were analyzed using paired t-tests and in-depth interviews with a subset of 45 participants were transcribed and analyzed thematically.

Results

Sumadhur significantly impacted (p < .05) norms related to pregnancy spacing and timing, and sex preference of children, as well as knowledge about family planning benefits, pregnancy prevention methods, and abortion legality. Family planning intent also increased among newly married women. Qualitative findings revealed improved family dynamics and gender equity, and shed light on remaining challenges.

Conclusions

Entrenched social norms surrounding fertility and family planning contrasted with participants’ personal beliefs, highlighting needed community-level shifts to improve reproductive health in Nepal. Engagement of influential community- and family-members is key to improving norms and reproductive health. Additionally, promising interventions such as Sumadhur should be scaled up and reassessed.
Studying Omega-nucleon-nucleon three-body states by realistic nucleon-nucleon and first principles Lattice QCD Omega-nucleon potentials in the cluster model
Authors: Etminan Faisal , Sanchuli Zahra
Published: October 2022

The Faddeev equations in coordinate space are solved to study the Omega-nucleon-nucleon and Omega-Omega-nucleon three-body systems using the latest Omega-nucleon and Omega-Omega interactions developed by the HAL QCD Collaboration (Omega is a decouplet baryon consists three strange quark). We calculate the binding energy of the Omega-nucleon-nucleon system by examining three nucleon-nucleon (NN) potentials, i.e., modern realistic AV18 potential, Yukawa-type Malfliet-Tjon (MT) interaction, and Gogny-Pires-Tourreil (GPT) soft and local potential. We take into account the contribution of the Coulomb potential. Our numerical calculations for Omega-deuteron in maximum spin 5/2+ leads to ground state binding energy of 20.953, 19.368, and 20.439 MeV and matter radius of 1.097, 1.373, and 1.309 fm using MT, GPT, and AV18 NN potentials, respectively. In the case of Omega-deuteron (0)5/2+ system, our numerical analysis shows that considering higher partial waves than s wave in NN interactions leads to an increase of about 0.2 MeV using GPT and about 0.1 MeV reduction with AV18 potentials. We study the convergence of three-body binding energies in a cluster model using the hyperspherical harmonics method and investigate the geometrical properties of Omega-deuteron (0)5/2+ ground states.
Inflated endoplasmic reticulum and autophagy induction promoted death in aggressive cancer cells grown in adherent and in-vitro CTC conditions.
Authors: Khan Sameer Ullah , Fatima Kaneez , Singh Umed , Singh Parvinder Paul , Malik Fayaz
Published: October 2022

Cancer metastasis is the leading cause of death in cancer patients and is a major challenging aspect of cancer biology. Various adaptive molecular signaling pathways play a crucial role in cancer metastasis and later in the formation of secondary tumors. Aggressive cancer cells like Triple Negative breast cancer (TNBCs) are more inclined to undergo metastasis hence having a high recurrence rate and potential for secondary tumor formation. Such aggressive cancer cells have fewer treatment options available with poor prognoses. Metastatic cells in circulation known as circulating tumor cells (CTCs) could be an appealing alternative target for cancer therapy with potentially better outcomes. Cell cycle regulation and stress response of CTCs in blood has a crucial role in their survival and progression and thus may be considered therapeutically active hotspots. The cyclin D/cyclin-dependent kinase (CDK) pathway regulates cell cycle checkpoints, a process that is frequently dysregulated in cancer cells. Selective CDK inhibitors can limit the phosphorylation of cell cycle regulatory proteins by inducing cell cycle phase arrest, and thus may be an effective therapeutic strategy for aggressive cancer cells in their dividing phase at the primary or secondary site. However, during the floating condition, cancer cells halt their division process and proceed through the various steps of metastasis. Our study showed that a novel CDK inhibitor 4ab besides showing anti-proliferative activity in aggressive cancer cells also induces cell death by activating endoplasmic reticulum stress and strong autophagy induction in both adherent and floating conditions which resulted in cytoplasmic vacuolation (paraptosis) and ultimately resulted in cell death. Further our results showed that 4ab efficiently induced apoptosis in aggressive cancer cells by initiating the ER-mitochondrial membrane potential loss-JNK pathway. Further, our in vivo data showed a promising inhibitory effect of 4ab on aggressive 4T1 cells in tumor formation and metastasis. The above data gave us encouraging results to consider 4ab as a potential inhibitor for anti-metastatic therapeutic intervention.
Preparation of a MOF-based molecularly imprinted polymer microsphere by a sol-gel technique and its application to the extraction and separation of aucubin from Eucommia ulmoides
Authors: Luo Xiaoyue , Xu Guoqiang , Deng Wen , Liu Meijun , Zhou Xiaohui , Xiao Zhenyi , Li Hui
Published: October 2022

Development of novel adsorption material for enrichment and separation of the most challenging compounds from plants is interesting. Preparation of a MOF-based aucubin imprinted polymer was performed and it was applied to the extraction and separation of aucubin from Eucommia ulmoides, a Traditional Chinese Medicine. A sol-gel method was utilized to prepared the MIPs and this imprinted material was used as the stationary phase in liquid chromatography to perform separation and extraction of aucubin from plant. Frontal chromatography technique was utilized to SPE application for the polymers. Results indicated that the imprint material (EM@MIP3) obtained under the optimized conditions possessed a high imprinting factor (6.830) and a high selectivity toward the template, with α (selectivity factor) values of 4.931, 4.896 and 3.418 relative to bugle glucoside (BG), plantain glucoside (PG) and geniposide (GP), respectively. The saturated binding capacity for the template on the EM@MIP3 column was 95.16 mg g− 1. When the EM@MIP3 column can be utilized to on-line separation of aucubin from the extract of Eucommia ulmoides, more than 85% purity of aucubin product can be obtained, with a recovery higher than 95%. The proposed method also has a detection limit and a quantitation limit of 0.167 and 0.547 mg kg− 1 in the application to sample analysis, with a high analysis repeatability. In addition, the reusability for the EM@MIP3 polymer was satisfactory. This imprint material is expected to be developed into an efficient adsorption media for the separation and purification of natural product from plants.
Adaptation of Chinese perch (Siniperca chuatsi) to different levels of dietary carbohydrates
Authors: Zhang Qiwei , Zhang Yanpeng , Feng Hexiong , Liang Xu-Fang
Published: October 2022

This study was conducted to investigate the effects of dietary carbohydrate on growth performance, feed utilization, proximate compositions, and hepatic glucolipid metabolism in Chinese perch. Triplicate groups of Chinese perch (29.51 ± 0.24 g) were fed five isonitrogenous and isolipidic diets containing graded levels of carbohydrate (2.4%, 9.7%, 16.5%, 23.9%, and 30.1%) for 8 weeks. The results showed that 10.93% dietary carbohydrate level provided a maximum growth for Chinese perch based on second-order polynomial regression analysis of specific growth rate (SGR). Compared to 2.4%-carbohydrate group, moderate-carbohydrate (9.7%) group exhibited the increase in daily weight gain (DWG) and protein retention ratio(PER), and the decrease in feed conversion efficiency (FCR). Moreover, moderate-carbohydrate group showed the increase in the mRNA levels of phosphofructokinase (pfk) and citrate synthase (cs) involved in aerobic oxidation pathway, the increase in hepatic glycogen content, and no change in glucose level. Above results suggested that part carbohydrates may be converted into energy for growth by aerobic oxidation pathway, and the remaining carbohydrates may be converted into glycogen for storage to maintain glucose homeostasis in Chinese perch fed with moderate-carbohydrate diet. Differently, high-carbohydrate (23.9% and 30.1%) group showed the decrease in DWG and PER, and the increase in FCR,compared to 2.4%-carbohydrate group. Additionally, high-carbohydrate group presented the increase in the mRNA levels of glucose-6-phosphatase a (g6pca) and pyruvate carboxylase (pc) involved in gluconeogenesis, which caused the increase in plasma glucose level. However, other plasma indices related to TG-metabolite and its transport (total triglyceride, total cholesterol, and low-density lipoprotein) did not show difference, which combined with elevated fatty acid synthesis-related gene acetyl coA carboxylase α (accα) mRNA level resulted in excessive liver lipid deposition. Above results indicated that unregulated gluconeogenesis and invalidoutward transportation of liver TG-rich metabolites may account for the glucose intolerance of Chinese perch fed with carbohydrate-rich diet.
Localized wave solutions to a variable-coefficient coupled Hirota equation in inhomogeneous optical fiber
Authors: Song Ni , Shang H. J. , Zhang Y. F. , Ma W. X.
Published: October 2022

Higher-order localized waves for a variable-coefficient coupled Hirota equation describes the vector optical pulses in inhomogeneous optical fiber and are investigated via generalized Darboux transformation in this work. Based on its Lax pair and seed solutions, the localized wave solutions are calculated, evolution plots are constructed, and the dynamics of the obtained localized waves are analyzed through numerical simulation. It is observed that the first- and second-order localized waves interact with dark-bright solitons or breathers, and the functions α(t), β(t), and δ(t) determine the propagation shape of the localized waves. The presented results contribute to enriching the dynamics of localized waves in inhomogeneous optical fiber. Keywords: variable-coefficient coupled Hirota equation; generalized Darboux transformation; soliton; breather
Overexpression of chloroplastic Zea mays NADP-malic enzyme (ZmNADP-ME) confers tolerance to salt stress in Arabidopsis thaliana
Authors: Kandoi Deepika , Tripathy Baishnab C.
Published: October 2022

Plants with C4 photosynthesis efficiently assimilate CO2 under stress conditions. To probe this idea further, the cDNA of decarboxylating C4 gene, for the NADP-malic enzyme from Zea mays (ZmNADP-ME), was overexpressed in Arabidopsis thaliana under the control of 35S promoter. The amino acids and protein contents in the transgenics were lower than in the vector control (VC). In the transgenics, the decarboxylation of malate to pyruvate resulted in reduced presence of 4-carbon acids that serve as the carbon backbone for amino acid synthesis. Consequently, amino acid and protein content were lower in the transgenics than in the VC. As a result, the photosynthetic efficiency (Fv/Fm), electron transport rate (ETR), carbon assimilation rate, overall quantum yield and starch content were reduced in the transgenics. These resulted in lower Chl content, rosette diameter, fresh weight and dry weight of the transgenics than that of the VC. Conversely, the transgenics had higher photosynthetic rate under salt stress. The overexpressers had higher Chl and protein content, Fv/Fm, ETR, and biomass than the VC grown under 150mM NaCl. NADPH generated due to the overexpression of NADP-ME in the overexpressers must have been used to synthesize proline that protected plants from reactive oxygen species, increased glutathione peroxidase activity and decreased H2O2 content in the transgenics. The reduced membrane lipid peroxidation and lower malondialdehyde production resulted in better preservation of thylakoid integrity and membrane architecture in the transgenics under saline environment. Our results demonstrate the vital role of C4 gene(s) in protecting plants form abiotic stress.
A multi-factory collaborative iterated greedy algorithm for distributed flowshop scheduling with blocking constraint
Authors: Zhang Chenyao , Han Yuyan , Wang Yuting , Li Junqing , Gao Kaizhou
Published: October 2022

Due to the multiple factory production pattern is becoming increasingly apparent, the distributed permutation flowshop scheduling problem (DPFSP) and its extension are studied. In this study, we consider the no buffers between adjacent machines and the setup time of adjacent jobs in DPFSP, and formed a distributed blocking flowshop scheduling problem with sequence-dependent setup times, called DBFSP_SDST. To better study this problem, we first construct mixed-integer linear programming (MILP) and verify the correctness of MILP by using the Gurobi solver. Then, we proposed a multi-factory collaborative iterated greedy algorithm, called mIG to solve the above-formulated model. In mIG, a rapid initialization strategy is proposed to generate a solution with high quality by using refresh accelerated calculation. Two iterative processes are designed with a certain probability to increase the diversity of solutions. Furthermore, according to the distributed characteristic, cross-factory and factory-inner strategies are proposed in iterative process II, the two strategies cooperate with each other to generate new solutions, which balances the exploration and exploitation of the algorithm. Numerous experiments have been conducted to test the performance of mIG, and the computational results demonstrate that mIG has obvious superiority over the state-of-the-art algorithms for DBFSP_SDST.
Towards Data Fusion based Big Data Analytics for Intrusion Detection
Authors: Jemili Farah
Published: October 2022

Intrusion detection is seen as the most promising way for computer security. It is used to protect computer networks against different types of attacks. The major problem in the literature is the classification of data into two main classes: normal or intrusion. To solve this problem, several approaches have been proposed but the problem of false alarms is still present. To provide a solution to this problem, we have proposed a new intrusion detection approach based on data fusion. The main objective of this work is to suggest an approach of data fusion based Big Data analytics in order to detect intrusions; It is to build one dataset which combines various datasets and contains all the attacks’ types. This research consists in merging the heterogeneous datasets and removing redundancy information using Big Data analytics tools: Hadoop and Neo4j. In the next step, machine learning algorithms are implemented for learning. The first algorithm, called SSDM (Semantically Similar Data Miner), uses fuzzy logic to generate association rules between the different item sets. The second algorithm, called K2, is a score-based greedy search algorithm for learning Bayesian networks from data. Experimentation results prove that - in both cases - data fusion contributes to have very good results in terms of detection rates and false alarms.
Modeling interfacial tension of heptane + alcohol mixtures using cubic plus association equation of state plus simplified gradient theory
Authors: Hernández Ariel
Published: October 2022

This work has been dedicated to modeling the interfacial tension of the heptane + alcohol mixtures in the temperature range of 288.15 K to 333.15 K. The cubic plus association equation of state is applied to the liquid - vapor phase equilibrium calculations. The binary interaction parameters are obtained according to the experimental isothermal and isobaric phase equilibrium data. For the binary interaction parameters, correlations have been obtained as a function of temperature for isothermal phase equilibrium, and a constant value for isobaric phase equilibrium. The linear gradient theory is used as a predictive and adjustment approach to describe the interfacial tension of the heptane + alcohol mixtures. The influence parameters of the pure components and the symmetric parameters of the binary mixtures were correlated with the temperature. The results of this work show that the cubic plus association equation of state is capable of simultaneously representing the phase equilibrium and interfacial tension of the mixtures studied. The results obtained in the interfacial tension are in agreement with those published in the literature.
Numerical Investigation of the Regional Climate Effect of the Lake Nasser
Authors: Xiong Zhe , Wang Ping , Dai Xingang , Ramah Mohamed , Wahab Magdy Abdel
Published: October 2022

Lake Nasser is the largest artificial reservoir in the world, with a water area of about 5000–6000 km2. This study aims to investigate the impact of the Lake on the local or regional climate in Upper Egypt with its surroundings using a high-resolution regional climate model. The numerical experiment is conducted with the RIEMS model with a boundary condition constrained by reanalysis ERA5 for 2010–2012. Two experiments are performed with and without the lake at the surface. The results show that the lake plays a role similar to a smooth, wet, cooling island in the hot desert. The cooling comes from lake water evaporation, which decreases the daily temperature difference resulting from the drop in daily maximal temperature and increase in minimum temperature. The smoothness of the lake water has the surface moisture flow accelerated and has local potential precipitation decreased and increased farther with additional northward moisture flows near the surface induced by the lake. Finally, the mechanism of the lake's impact is explored with the difference in horizontal moisture flux represented by the streamlines, whose pattern approximately coincides with the corresponding precipitation difference during the period. The main finding is that the lake has a significant impact not only on the local climate but also on regional climate, especially regional precipitation. It leads to an additional decrease in precipitation over the lake basin and an increase farther from the basin. This is the first time that a regional climate effect of an artificial lake has been proved by numerical experiment.
Evaluation of rock burst intensity of cloud model based on CRITIC method and order relation analysis method
Authors: Zhang Qianjun , Liu Chuanju , Guo Sha , Wang Wentong , Luo Haoming
Published: October 2022

Rock burst has always been a major problem for deep underground engineering with high stress. In order to effectively predict and evaluate rock burst intensity grade of underground rock mass engineering. In this paper, a cloud model (CM) rock burst intensity evaluation method based on CRITIC method and order relation analysis method (G1) is established. Firstly, the rock's uniaxial compressive strength σc, tangential stress σθ, uniaxial tensile strength σt, ratio of uniaxial compressive strength to tensile strength σc/σt (brittleness coefficient), ratio of tangential stress to uniaxial compressive strength σθ/σc (stress coefficient), elastic deformation energy index Wet and buried depth H are selected as evaluation indexes of rock burst intensity. 95 groups of rock burst measured data at home and abroad are selected, and the objective weight and subjective weight of each index are calculated by using CRITIC method and G1 method respectively. The combined weighting method of game theory is used to calculate the final weight and analyze the sensitivity of each evaluation index. MATLAB software was used to calculate the membership degree of different rock burst grades, and compared with the evaluation results of CRITIC-CM method and G1-CM method and the actual grades. And the rock burst classification ability of the model is analyzed. Finally, the rock burst case of W39 line in Chengchao Iron Mine was analyzed by using this model. The research results show that the rock burst evaluation results based on CRITIC-G1-CM are basically consistent with the actual rock burst grade, and the rock burst intensity grade evaluation model has good practicability and reliability.
Research on ICT Development and Training for Teachers in the Western Province of Sri Lanka.
Authors: de Silva Arosha , de Silva Arosha
Published: October 2022

This research aims to evaluate the outcome of felicitating the ICT training and development program for teachers in the western province of Sri Lanka. Teachers face many challenges and drawbacks in teaching in a technologically advancing world. Due to the lack of technological knowledge and skill, teachers are unable reach their highest potential in the field of teaching. This actionresearch reviews the development of the teacher’s knowledge and skill in ICT. For this study, teachers were able to give an account of their experiences in the ICT training and development program. A mixed method of data collection and analysis was used for this research, first a qualitative method followed by a quantitative method. Through the findings of this research it was revealed that a majority of teachers had benefited from the ICT training and development program thereby it is necessary that measures be taken to conduct more ICT training and development programs for teachers. Teachers who had undergone ICT training and development were better equipped and confident to face the technologically advancing education system.
The potential protective effect of C-phycocyanin from new extremophile strain Phormidium versicolor NCC-466 against cadmium-induced nephrotoxicity in HEK293 cells and rats kidney
Authors: Guermazi Wassim , Athmouni Khaled , Diwani Nouha , Bidhi Mariem , Aloulou Ahmed , Ayadi Habib , Gammoudi Sana
Published: October 2022

This research focused on the nephroprotective activity of phycocyanin (C-PC) a bleu protein pigment extracted from new halophile cyanobacteria Phormidium versicolor against cadmium induced renal damage in vitro and in vivo. In vitro study, 25 µg /ml C-PC was assessed for nephroprotective activity against 35 µg /ml of cadmium (Cd) induced toxicity in HEK293 cells by determining cell viability. The effect of Cd on lipid peroxidation and antioxydant capacity (SOD, GPx and CAT) was assessed. The results showed that cells exposed to Cd and treated with C-PC caused a significant increase in cell viability reached 90%. Morphological studies also supported the protective action of C-PC. In addition, in vivo study showed that the C-PC treated rats significantly prevented Cd-induced elevation of creatinine and urea concentrations. Antioxydant parameters catalase (CAT), Superoxyde Dismutase (SOD) and Glutathione peroxydase (GSH-Px) of rat kidneys treated by C-PC were significantly antagonized for the pro-oxydant effect of Cd-exposure. This study suggests that P.versicolor phycocyanin has a significant in vitro and in vivo antioxidant potential on Cd-caused HEK293 and rats kidney.
Burden of neglected tropical diseases and access to medicine and diagnostics in Ethiopia: A scoping review
Authors: Semahegn Agumasie , Manyazewal Tsegahun , Getachew Eyerusalem , Fekadu Bethelhem , Assefa Esubalew , Kassa Munir , Davey Gail , Hopekins Michael , Araya Mesele , Woldehanna Tassew , Hanlon Charlotte , Fekadu Abebaw
Published: October 2022

Background The World Health Organization’s new roadmap for neglected tropical diseases (NTDs) 2021–2030 aims to prevent, control, eliminate or eradicate 20 tropical diseases that are affecting the lives of 1.5 billion people worldwide. Ethiopia experiences a high burden of these diseases, but current access to diagnostics, medicine and /or care has been little explored to inform the country’s NTD strategic plan. This scoping review aimed to map and characterize the burden of NTDs and challenges in access to diagnostics, medicine and /or care in Ethiopia. Methods A systematic search was conducted in PubMed, Cochrane Library, and Google Scholar from January 2000 until May 2022 and without restrictions of language or study design. The Preferred Reporting Items for Systematic Reviews and Meta-Analysis Extension for Scoping Review (PRISMA-ScR) was followed and the findings were synthesized narratively. Results The search resulted in 4,532 articles, of which 105 met the inclusion criteria and were included in the scoping review under three themes: burden of NTDs, access to medicine/drug, care and diagnostics. Although gains have been made in the prevention and control of NTDs in Ethiopia, the burden remains high and progress in access to diagnostics, medicine/drugs, and/or care is very slow. Poverty, poor quality of life, and underfunding of NTD programs decelerate the process of NTD elimination program in the country. Conclusions The review identified a considerable number of studies on the burden of NTDs in Ethiopia and strategies for diagnosis, treatment and/or care; however, there is a paucity of evidence on the suitability and potential benefits of novel diagnostic technologies and medicines in the country. A regular review and analysis of such country-level evidence is important to inform the country NTDs roadmap and local implementation strategies.
Level of Knowledge regarding Monkeypox among Peruvian Physicians during the 2022 Outbreak: A Cross-Sectional Study
Authors: Gonzales-Zamora Jose , Soriano-Moreno David R. , Soriano-Moreno Anderson N. , Ponce-Rosas Linda , Sangster-Carrasco Lucero , De-Los-Rios-Pinto Abraham , Benito-Vargas Raysa M. , Murrieta-Ruiz Valentina , Morocho-Alburqueque Noelia , Caira-Chuquineyra Brenda , Fernandez-Guzman Daniel , Ccami-Bernal Fabricio , Quispe-Vicuña Carlos , Alarcon-Parra Mariano , Pinedo-Soria Antony , Alave Jorge
Published: October 2022

Introduction:
Monkeypox has become a public health emergency given the rapid spread of the disease worldwide. Due to the high incidence of this disease in Peru and the poor knowledge about monkeypox among healthcare workers in non-endemic countries, it is crucial to determine the knowledge status of Peruvian physicians.
Methodology:
We conducted an analytical cross-sectional study based on an online survey from August to September 2022. Physicians who had a medical license and lived and practiced Medicine in Peru were included. To evaluate the factors associated with a higher level of knowledge, we used crude (cPR) and adjusted (aPR) prevalence ratios with 95% confidence intervals (95% CI) using Poisson regression.
Results
We included 463 physicians. The mean age was 36.6 (SD: 10.3) years, and most were male (58.1%). Regarding knowledge, the median knowledge score was 14 [IQR: 13 to 15] out of 17 points. In terms of knowledge gaps, only 60.7% of the participants knew that there was an FDA-approved vaccine for monkeypox, 49.0% of participants knew about monkeypox proctitis and 33.3% acknowledged that it could be transmitted by the bite of an infected rodent. We found that taking care of patients with monkeypox (aPR: 1.39; 95% CI: 1.13 to 1.72) was associated with a higher knowledge (> p50) while living in the jungle (aPR: 0.61; 95% CI: 0.41 to 0.91) was associated with lower knowledge (< p50).
Conclusions
Our study showed a high level of knowledge about monkeypox among Peruvian physicians. However, educational campaigns may be necessary, especially for physicians from the jungle and those who do not have clinical experience in monkeypox.
Spin-up time and internal variability analysis for overlapping time slices in a regional climate model
Authors: Gullon Alvaro Lavin , Milovac Josipa , Dı́ez Markel Garcı́a , Fernández Jesús
Published: October 2022

Long-term regional climate simulations are computationally very 8 costly. One way to improve their computational efficiency is to split them into 9 overlapping time slices, which can then be run in parallel. Although this proce10 dure reduces the cost, sufficient spin-up must be left at the start of each slice. 11 In any case, discontinuities will occur due to internal variability where two dif12 ferent slices join. In this study, we explore the relative role of spin-up time and 13 internal variability in the discontinuities of overlapping time slice simulations 14 and their effect on the simulated climate. This analysis has implications also 15 for non-overlapping time slices, commonly used in very high resolution climate 16 modelling, where long transient simulations cannot be afforded. We show that 17 discontinuities are negligible for surface and upper-air variables, but they are 18 noticeable in variables with long response times, such as soil moisture or snow 19 depth. For these variables, differences between the slices are mainly attributed 20 to internal variability, but also to insufficient spin-up time, depending on the 21 region. In general, the results show that the overlapping time slice approach 22 is valid to accomplish long term regional climate simulations.
Mapping the Queer Body: Queer Tropes and Malayalam Cinema
Authors: Rajesh James  , Sathyaraj Venkatesan
Published: October 2022

The narrative logic of mainstream Malayalam cinema is often predicated on heteronormative values and homophobic social practices. Though representations of LGBTQIA+ (lesbian, gay, bisexual, transgender, queer, intersex, asexual and agender) desires (both individual and collective) have been subject to changes particularly after the historical verdict of 2018, mainstream Malayalam cinema is quite reluctant to explore “the love that had for so long been left out in the cold” (Griffiths 2008, 130). Barring a few exceptions, most of the films produced in Kerala (since Malayalam cinema’s inception in 1928) have characterised LGBTQIA+ as aberrant, abnormal, or deviant. Having said that, there have been considerable efforts from progressive filmmakers to critique and subvert the homophobic sentiments of the society and engage with queer desires in Malayalam cinema either denotatively or connotatively. This has been made possible due to their exposure to variegated cultural values as a result of the changing socio-economic and political conditions. By identifying three major tropes (the closeted queer body, the stereotyped queer body, and the visible queer body) in queer filmic representations, the paper attempts to map the many expressions of queer subjectivities in Malayalam cinema. In the process, the article demonstrates how queer cinema in Malayalam disrupts heteronormativity using its queer aesthetics.
New Communication Trends in Education: digital technologies and artificial intelligence
Authors: Sharkov F. I. , Abisheva V. T. , Luchina M. A. , Potapchuk V. A. , Ramazanova Zh. S.
Published: October 2022

The article discusses new communication trends in education and reveals major trends in the media sphere, in particular, new data transfer rates, the use of artificial intelligence, the digital revolution in educational formats. The authors note that innovative technologies play an important role in the development of a culture of learning and open up new opportunities for professional development. These should increase the efficiency of the educational process, offer flexibility in the methods of obtaining knowledge, reveal in a new way the potential and social role of the teacher, acting in a new educational paradigm. The digitalization of the educational process, the inclusion of virtual technologies and artificial intelligence in the development of knowledge, the development of software are turning into a new educational industry, becoming a factor that effectively influences the depth of knowledge acquisition and determines the development dynamics of modern advanced universities and ed-tech companies. Based on the analysis of the recent publications and the following universal socio-cultural study with the participation of scientists from Russia, Kazakhstan and the international research company Ipsos – Сomcon, the authors outline key communication trends and scenarios for the development of education using digital technologies and artificial intelligence in the foreseeable future.
Sensorimotor and Perceptual Processes in Children of Primary School Age with Multiple Developmental Disorders
Authors: Tolkacheva Anastasiya , Belogai Ksenia
Published: October 2022

The article focuses on sensorimotor and perceptual processes in primary school children with multiple developmental disorders. The study involved 40 children aged 9–11 with multiple developmental issues. All the participants studied at the Secondary School of Psychological and Pedagogical Support No. 101 (Kemerovo, Russia). The experiment relied on the method developed by N. I. Ozeretskiy and M. O. Gurevich as the main diagnostic tool. The method combines a set of diagnostic tasks aimed at measuring the level of motor and perceptual development in children. The experimental study also included elements of the neuropsychological approach. The authors designed and conducted a series of practice sessions on the development of sensorimotor and perceptual processes. The neuropsychological exercises developed purposeful voluntary actions with objects and materials, improved available sensory experience, increased visual-motor coordination, sharpened the ability to navigate in various physical environments, and improved body control. They facilitated the compensation of residual reflexes, as well as the development of speech and general motor rhythmization. The exercises involved orthopedic mats, massage balls, tasks on visual-motor perception and integration, Balametrics cerebellar stimulation, etc. Statistic results showed a positive trend in the sensorimotor and perceptual processes, except for complex forms of space and time perception.
Developing Professionally Important Personal Qualities of a Future Mining Engineer in the Conditions of Dual Training in Kuzbass
Authors: Grigor'eva Natal'ya
Published: October 2022

Kuzbass mining managers have certain requirements for professional skills of future mining engineers. Along with theoretical and practical knowledge, they expect university graduates to possess professionally important personal qualities that allow mining engineers to work in potentially dangerous environment and bear responsibility for themselves and their team. Dual training is a form of social partnership between an educational institution and a large industrial enterprise. The article provides mechanisms for interaction between social partners and describes the possibilities of dual training as a means of developing professionally important personal qualities. The author reviewed foreign and Russian publications in the field of dual training and analyzed regulatory documents, requirements of mining managers, curricula of Mining university programs, personality characteristics of students of the practice-oriented specialties, and the socio-psychological climate at Kuzbass mining enterprises. The research resulted in an adjustment project for Mining majors and curricula developed by an expert group of university staff and mining enterprises.
Pedagogical Staff and Digital Competencies: Professional Development in the Academic Digitalization
Authors: Shirokolobova Anastasiya , Larionova Yuliya , Achkasova Oksana , Shirokolobov Georgiy
Published: October 2022

Modern university teaching staff require digital competencies, but their development in the digitalization epoch still remains understudied. The organization and content of digital training in the system of continuing pedagogical education also need a unified approach. The article focuses on digital skill development in faculty members as part of life-long learning. The authors defined the concept of digital competency and created a professional retraining program of Digital Technologies in Teaching, which they put to an evaluation test. The course lasted 72 hours and consisted of several stages and a final assessment. The research objective was to identify the level of digital competencies in the course graduates. The study involved a review of relevant scientific publications, an analysis of normative documents, and various methods of observation. The program provided a well-structured learning process and enabled the participants to create digital syllabuses of their own. It can be recommended for teaching staff of all education levels who would like to increase their digital competency.
On Some Problems of Qualification of Lawful Infliction of Harm in Case of Environmental Tort
Authors: Peraladov Andrey
Published: October 2022

The issues related to the negative impact on the environment with the permitted use of natural resources, when the user of natural resources has a permit for nature use and a construction project that has passed the procedure for agreeing on the state environmental review, are being investigated. The purpose of the paper is to establish the possibility of qualifying the actions of a nature user within the framework of his permitted activities as lawful infliction of harm to the natural environment. The injustice and unacceptability of the approaches formed in law enforcement practice on imposing responsibility on any user of nature for harm caused to the environment in the process of carrying out permitted economic activities is revealed. In the comparative legal aspect, the inquisitorial nature of approaches in domestic law enforcement is substantiated, which contradicts modern legal guarantees for ensuring the functioning of business, which are characteristic of foreign legal orders. There is an unfair distribution of the burden of proof and the establishment of de facto legal presumptions not provided for by law in relations from environmental torts. In order to establish the fair liability of the tortfeasor, when considering cases of environmental torts, it is necessary to take into account the fact that state regulatory authorities have issued a permit for subsoil use, because such an act authorizes the use of natural resources and, accordingly, allows for environmental degradation. In the article, the author formulates the criteria for lawful infliction of harm and factors that should affect the amount of liability of the nature user in connection with causing harm to the environment.
The Evolution of the Legislative Regulation of the Confiscation of Property in the Domestic Legal System
Authors: Gorbachev Ivan
Published: October 2022

The institute of confiscation of property serves as a historically integral tool, known since ancient times, to fight crime. The contradictory legal nature and ambiguous nature have led to a trend of variability of its legal status in the domestic criminal law system. An objective assessment of the role and place of confiscation of property in modern Russia requires consideration of the rich historical experience of the formation and development of this institution, which is the purpose of this work. The methodological basis of the study is represented by a number of traditional, general scientific (analysis, synthesis, comparison, forecasting) and private scientific methods of cognition. Among them, the most common were the historical method, which made it possible to trace the specifics of the formation of the institution of confiscation in domestic criminal law, the comparative legal method, with the help of which it was possible to compare the norms of different historical eras that regulate the legal status of confiscation. The formal legal method made it possible to prove the expediency of maintaining the legal status of confiscation in the Russian legal system. As a result of the study, the features of the criminal law regulation and application of property confiscation in the pre-revolutionary and Soviet state are considered in detail. The relationship between the economic needs of the country and the regulation, content and procedure for the execution of property confiscation is substantiated. The author's position on the need to preserve confiscation as another measure of a criminal law nature is argued. The results obtained can be used in the process of further theoretical understanding of the institution of property confiscation.
Pengaruh Herding Bias dan Overconfidence Bias terhadap Pengambilan Keputusan Investasi
Authors:   Bali Creative Industry Center, Kementerian Perindustrian Indonesia, Kesiman Kertalangu, Kec. Denpasar Timur, Kota Denpasar, Bali & Fakultas Ekonomi, Universitas Pendidikan Ganesha, Jl. Udayana No.11, Banjar Tegal, Singaraja, Kabupaten Buleleng, Bali 81116, Rona I Wayan , Sinarwati Ni Kadek ,   Fakultas Ekonomi, Universitas Pendidikan Ganesha, Jl. Udayana No.11, Banjar Tegal, Singaraja, Kabupaten Buleleng, Bali 81116
Published: October 2022

This research study was conducted to analyze the effect of herding bias and overconfidence bias on investment decision-making. This research used quantitative methods with data collection techniques using questionnaires distributed to individual investors who have experience with a total sample of about 124 respondents. The technique used for sampling in this research was simple random sampling. The research analysis methods used the classical assumption test such as normality test, multicollinearity test, heteroscedasticity test, and multiple linear regression analysis, namely hypothesis testing. According to the analysis, the result of this research is that herding bias and confidence bias had a positive and significant effect on investment decision-making.
Keputusan Etis Konsultan Pajak: Pentingnya Tanggung Jawab Sosial dan Machiavellianisme
Authors:   Program Studi Akuntansi, Trisakti School of Management Jl. Kyai Tapa No.20, RT.1/RW.9, Tomang, Kec. Grogol petamburan, Kota Jakarta Barat, Daerah Khusus Ibukota Jakarta 11440, Christian Yesheca Gracia , Susanto Yulius Kurnia ,   Program Studi Akuntansi, Trisakti School of Management Jl. Kyai Tapa No.20, RT.1/RW.9, Tomang, Kec. Grogol petamburan, Kota Jakarta Barat, Daerah Khusus Ibukota Jakarta 11440
Published: October 2022

This research objective is to get evidence about the effect of perception of the importance of ethical and social responsibility, Machiavellianism, ethical reasoning, idealism, experience, and professional commitment to ethical decision-making of tax consultants. Data were obtained from the questionnaire. This research used the convenience sampling method. This study used 60 tax consultants as the study samples in DKI Jakarta, and the data were analyzed using multiple regression analysis. This research showed that the perception of the importance of ethical and social responsibility, Machiavellianism, and ethical reasoning affects the ethical decision-making of tax consultants. The results showed that tax consultants with a high perception of the importance of ethical and social responsibility and ethical reasoning and low perception of Machiavellianism support that tax consultants conduct ethical decision-making. Meanwhile, idealism, experience, and professional commitment do not affect tax consultants' ethical decision-making. The implications of this research are for tax consultants to maintain the perception of the importance of ethics and social responsibility, and ethical considerations to make ethical decisions. The limitation of this study is that it uses respondents' perceptions of questions related to all variables. This finding shows that there is still a subjective element of the respondents.