bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure S4. c-ABL Regulates Cell Cycle Process. from Cervical Cancer Growth Is Regulated by a c-ABL–PLK1 Signaling Axis
Authors: Yang Xu , Chen Gang , Li Wei , Peng Changmin , Zhu Yue , Yang Xiaoming , Li Teng , Cao Cheng , Pei Huadong
Published: April 2023

A, HeLa cells were transfected with c-ABL-specific siRNA or nonspecific control siRNA. After 12hrs transfection, HeLa cells were synchronized by a double thymidine treatment. Cell-cycle distributions were determined by flow cytometry analysis. B, HeLa cells were treated with the indicated shRNAs, then released into mitosis by using thymidine-nocodazol method. The p-H3S10-positive cells were counted at the indicated time points. Data are shown as mean {plus minus} s.e.m. (n=500). C, Representative immunofluorescence imagines of p-H3S10 staining cells were shown. Scale bar: 50 μm. D, HeLa cells were transfected with PLK1 shRNA together with Plk1 or Y425F mutant, and synchronized by a double-thymidine arrest. Cells were released into nocodazol, and collected at the indicated times after release. The levels of the indicated proteins were determined by western blot analysis.
Supplementary Figure S3 from Enriching the Housing Environment for Mice Enhances Their NK Cell Antitumor Immunity via Sympathetic Nerve–Dependent Regulation of NKG2D and CCR5
Authors: Song Yanfang , Gan Yu , Wang Qing , Meng Zihong , Li Guohua , Shen Yuling , Wu Yufeng , Li Peiying , Yao Ming , Gu Jianren , Tu Hong
Published: April 2023

Influence of EE on NK population in the peripheral blood and spleen of tumor-bearing mice.
Supplementary Figure S1 from Enriching the Housing Environment for Mice Enhances Their NK Cell Antitumor Immunity via Sympathetic Nerve–Dependent Regulation of NKG2D and CCR5
Authors: Song Yanfang , Gan Yu , Wang Qing , Meng Zihong , Li Guohua , Shen Yuling , Wu Yufeng , Li Peiying , Yao Ming , Gu Jianren , Tu Hong
Published: April 2023

Exposure to EE reduces anxiety-like behavior, decreases body weight, and increases food intake in mice.
Supporting figure legends and methods from Novel Selective Agents for the Degradation of Androgen Receptor Variants to Treat Castration-Resistant Prostate Cancer
Authors: Ponnusamy Suriyan , Coss Christopher C. , Thiyagarajan Thirumagal , Watts Kate , Hwang Dong-Jin , He Yali , Selth Luke A. , McEwan Iain J. , Duke Charles B. , Pagadala Jayaprakash , Singh Geetika , Wake Robert W. , Ledbetter Christopher , Tilley Wayne D. , Moldoveanu Tudor , Dalton James T. , Miller Duane D. , Narayanan Ramesh
Published: April 2023

Captions for supporting data and detailed methods for chemical synthesis and standard biochemical assays
Supplementary Figure S1 from Tankyrase-Binding Protein TNKS1BP1 Regulates Actin Cytoskeleton Rearrangement and Cancer Cell Invasion
Authors: Ohishi Tomokazu , Yoshida Haruka , Katori Masamichi , Migita Toshiro , Muramatsu Yukiko , Miyake Mao , Ishikawa Yuichi , Saiura Akio , Iemura Shun-ichiro , Natsume Tohru , Seimiya Hiroyuki
Published: April 2023

TNKS1BP1 depletion induces cofilin phosphorylation and enhances cell invasion and focal adhesion in pancreatic cancer cells.
Video S2, Related to Figure 2 from RORγt+ Innate Lymphoid Cells Promote Lymph Node Metastasis of Breast Cancers
Authors: Irshad Sheeba , Flores-Borja Fabian , Lawler Katherine , Monypenny James , Evans Rachel , Male Victoria , Gordon Peter , Cheung Anthony , Gazinska Patrycja , Noor Farzana , Wong Felix , Grigoriadis Anita , Fruhwirth Gilbert O. , Barber Paul R. , Woodman Natalie , Patel Dominic , Rodriguez-Justo Manuel , Owen Julie , Martin Stewart G. , Pinder Sarah E. , Gillett Cheryl E. , Poland Simon P. , Ameer-Beg Simon , McCaughan Frank , Carlin Leo M. , Hasan Uzma , Withers David R. , Lane Peter , Vojnovic Borivoj , Quezada Sergio A. , Ellis Paul , Tutt Andrew N.J. , Ng Tony
Published: April 2023

Time lapse microscopy experiment of sorted NKp46-ILC3 cells (CD3-, CD11c-, B220-, NKp46-, CD127+, CD90.2+) co-cultured with MSC cells as described in Figure 2B. High magnification (Ã-40) video shows the prolonged interaction of NKp46-ILC3 and MSC cells upon contact.
Figure S2 from Pathologic Oxidation of PTPN12 Underlies ABL1 Phosphorylation in Hereditary Leiomyomatosis and Renal Cell Carcinoma
Authors: Xu Yang , Taylor Paul , Andrade Joshua , Ueberheide Beatrix , Shuch Brian , Glazer Peter M. , Bindra Ranjit S. , Moran Michael F. , Linehan W. Marston , Neel Benjamin G.
Published: April 2023

Classical PTP expression, H2O2 sensitivity and irreversible oxidation in FH-deficient PRCC cell lines.
Table S1 from Syntaphilin Ubiquitination Regulates Mitochondrial Dynamics and Tumor Cell Movements
Authors: Seo Jae Ho , Agarwal Ekta , Bryant Kelly G. , Caino M. Cecilia , Kim Eui Tae , Kossenkov Andrew V. , Tang Hsin-Yao , Languino Lucia R. , Gabrilovich Dmitry I. , Cohen Andrew R. , Speicher David W. , Altieri Dario C.
Published: April 2023

Pathway analysis of SNPH-associated proteins
Figure S2 from Syntaphilin Ubiquitination Regulates Mitochondrial Dynamics and Tumor Cell Movements
Authors: Seo Jae Ho , Agarwal Ekta , Bryant Kelly G. , Caino M. Cecilia , Kim Eui Tae , Kossenkov Andrew V. , Tang Hsin-Yao , Languino Lucia R. , Gabrilovich Dmitry I. , Cohen Andrew R. , Speicher David W. , Altieri Dario C.
Published: April 2023

SNPH ubiquitination regulates tubulin binding
Supplementary Figure 5 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma
Authors: Ravindran Menon Dinoop , Luo Yuchun , Arcaroli John J. , Liu Sucai , KrishnanKutty Lekha Nair , Osborne Douglas G. , Li Yang , Samson Jenny Mae , Bagby Stacey , Tan Aik-Choon , Robinson William A. , Messersmith Wells A. , Fujita Mayumi
Published: April 2023

Luciferase reporter assay using Sox2 response elements. Related to Figure 6
Supplementary Figure 4 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma
Authors: Ravindran Menon Dinoop , Luo Yuchun , Arcaroli John J. , Liu Sucai , KrishnanKutty Lekha Nair , Osborne Douglas G. , Li Yang , Samson Jenny Mae , Bagby Stacey , Tan Aik-Choon , Robinson William A. , Messersmith Wells A. , Fujita Mayumi
Published: April 2023

Effect of BAY11-7082 on Sox2 subcellular localization. Related to Figure 5
Supplementary Figure 3 from CDK1 Interacts with Sox2 and Promotes Tumor Initiation in Human Melanoma
Authors: Ravindran Menon Dinoop , Luo Yuchun , Arcaroli John J. , Liu Sucai , KrishnanKutty Lekha Nair , Osborne Douglas G. , Li Yang , Samson Jenny Mae , Bagby Stacey , Tan Aik-Choon , Robinson William A. , Messersmith Wells A. , Fujita Mayumi
Published: April 2023

Effect of CDK1 inhibitor on spheroid formation, tumor growth and initiation of melanoma cell lines. Related to Figure 3.
Supplementary Figure 4 from Helicase-Driven Activation of NFκB-COX2 Pathway Mediates the Immunosuppressive Component of dsRNA-Driven Inflammation in the Human Tumor Microenvironment
Authors: Theodoraki Marie-Nicole , Yerneni Saigopalakrishna , Sarkar Saumendra N. , Orr Brian , Muthuswamy Ravikumar , Voyten Jamie , Modugno Francesmary , Jiang Weijian , Grimm Melissa , Basse Per H. , Bartlett David L. , Edwards Robert P. , Kalinski Pawel
Published: April 2023

Uniform activation of immunostimulatory and suppressive inflammatory mediators, including COX-2, by different TLR ligands.
Supplementary Data from Lactic Acid Accumulation in the Tumor Microenvironment Suppresses 18F-FDG Uptake
Authors: Türkcan Silvan , Kiru Louise , Naczynski Dominik J. , Sasportas Laura S. , Pratx Guillem
Published: April 2023

Contains Supplementary Methods, Figures and Tables
Figure S7 from Twist1 Regulates Vimentin through Cul2 Circular RNA to Promote EMT in Hepatocellular Carcinoma
Authors: Meng Jing , Chen Shuang , Han Jing-Xia , Qian Baoxin , Wang Xiao-Rui , Zhong Wei-Long , Qin Yuan , Zhang Heng , Gao Wan-Feng , Lei Yue-Yang , Yang Wei , Yang Lan , Zhang Chao , Liu Hui-Juan , Liu Yan-Rong , Zhou Hong-Gang , Sun Tao , Yang Cheng
Published: April 2023

Figure S7. The formation and sequences of circ-10720 in mice. (A)Schematic diagram of the formation of circRNA-10720 in mice. (B) The sequence alignment of circRNA-10720 in human (Query 1) and mice (Sbjct 1).
Figure S1 from Twist1 Regulates Vimentin through Cul2 Circular RNA to Promote EMT in Hepatocellular Carcinoma
Authors: Meng Jing , Chen Shuang , Han Jing-Xia , Qian Baoxin , Wang Xiao-Rui , Zhong Wei-Long , Qin Yuan , Zhang Heng , Gao Wan-Feng , Lei Yue-Yang , Yang Wei , Yang Lan , Zhang Chao , Liu Hui-Juan , Liu Yan-Rong , Zhou Hong-Gang , Sun Tao , Yang Cheng
Published: April 2023

Figure S1. Peak analyses of Twist1 ChIP-Seq Data Sets. (A) Heat map view of signals observed in the presence of Twist1. (B) Density graph of the Twist1 peak locations in relation to the nearest transcriptional start sites (TSS). The x-axis represents the distance from the peak center to the nearest TSS, where zero is the position of the TSS. The y-axis represents the proportion of detected bindings that are located within each distance interval. (C) Twist1 ChIP-seq peak density on the Cul2.
Table S1 from IL-6 Mediates Cross-Talk between Tumor Cells and Activated Fibroblasts in the Tumor Microenvironment
Authors: Karakasheva Tatiana A. , Lin Eric W. , Tang Qiaosi , Qiao Edmund , Waldron Todd J. , Soni Monica , Klein-Szanto Andres J. , Sahu Varun , Basu Devraj , Ohashi Shinya , Baba Kiichiro , Giaccone Zachary T. , Walker Sarah R. , Frank David A. , Wileyto E. Paul , Long Qi , Dunagin Margaret C. , Raj Arjun , Diehl J. Alan , Wong K.K. , Bass Adam J. , Rustgi Anil K.
Published: April 2023

sequences for qPCR probes used in the manuscript
Figures S1-S5 from Caveolae-Mediated Endocytosis Is Critical for Albumin Cellular Uptake and Response to Albumin-Bound Chemotherapy
Authors: Chatterjee Moumita , Ben-Josef Edgar , Robb Ryan , Vedaie Marall , Seum Star , Thirumoorthy Krishnan , Palanichamy Kamalakannan , Harbrecht Matthew , Chakravarti Arnab , Williams Terence M.
Published: April 2023

Supplemental data that lists how standard curve for mass spectrometry was made (S1), individual nab-paclitaxel IC50 data (S2), electron microscopy images showing how Cav-1 depletion ablates caveolae (S3), additional cell line data showing response to paclitaxel or nab-paclitaxel (S4), and additional confocal microscopy images of low Cav-1 expressing cell lines (S5).
Table S2 from Tethering IL2 to Its Receptor IL2Rβ Enhances Antitumor Activity and Expansion of Natural Killer NK92 Cells
Authors: Jounaidi Youssef , Cotten Joseph F. , Miller Keith W. , Forman Stuart A.
Published: April 2023

Impact of direct contact with cancer cells on NK cells expression profiles of natural cytotoxicity and effectors.
Figure S1 from Tethering IL2 to Its Receptor IL2Rβ Enhances Antitumor Activity and Expansion of Natural Killer NK92 Cells
Authors: Jounaidi Youssef , Cotten Joseph F. , Miller Keith W. , Forman Stuart A.
Published: April 2023

Representation of the chimera CIRB.
Supplemental Methods from TumorMap: Exploring the Molecular Similarities of Cancer Samples in an Interactive Portal
Authors: Newton Yulia , Novak Adam M. , Swatloski Teresa , McColl Duncan C. , Chopra Sahil , Graim Kiley , Weinstein Alana S. , Baertsch Robert , Salama Sofie R. , Ellrott Kyle , Chopra Manu , Goldstein Theodore C. , Haussler David , Morozova Olena , Stuart Joshua M.
Published: April 2023

More detail into the methodology behind the resource are provided as well as proof-of-concept benchmarks.
Figure S1 from Extracellular Matrix Protein Tenascin C Increases Phagocytosis Mediated by CD47 Loss of Function in Glioblastoma
Authors: Ma Ding , Liu Senquan , Lal Bachchu , Wei Shuang , Wang Shuyan , Zhan Daqian , Zhang Hao , Lee Richard S. , Gao Peisong , Lopez-Bertoni Hernando , Ying Mingyao , Li Jian Jian , Laterra John , Wilson Mary Ann , Xia Shuli
Published: April 2023

Figure S1 shows cleaved caspase 3 staining and quantification in CD47 WT and CD47 KO xenografts.
Supplementary Table S1 from Comprehensive Phenotypic Characterization of Human Invasive Lobular Carcinoma Cell Lines in 2D and 3D Cultures
Authors: Tasdemir Nilgun , Bossart Emily A. , Li Zheqi , Zhu Li , Sikora Matthew J. , Levine Kevin M. , Jacobsen Britta M. , Tseng George C. , Davidson Nancy E. , Oesterreich Steffi
Published: April 2023

Antibody and shRNA sequence information.
Figure S2 from A Novel Small-Molecule Inhibitor of MRCK Prevents Radiation-Driven Invasion in Glioblastoma
Authors: Birch Joanna L. , Strathdee Karen , Gilmour Lesley , Vallatos Antoine , McDonald Laura , Kouzeli Ariadni , Vasan Richa , Qaisi Abdulrahman Hussain , Croft Daniel R. , Crighton Diane , Gill Kathryn , Gray Christopher H. , Konczal Jennifer , Mezna Mokdad , McArthur Duncan , Schüttelkopf Alexander W. , McConnell Patricia , Sime Mairi , Holmes William M. , Bower Justin , McKinnon Heather J. , Drysdale Martin , Olson Michael F. , Chalmers Anthony J.
Published: April 2023

Confirmation of tumour volume (MRI), levels of circulating BDP-9066 and CT guided RT
Supplemental figure legends from TRPM2 Mediates Neutrophil Killing of Disseminated Tumor Cells
Authors: Gershkovitz Maya , Caspi Yaki , Fainsod-Levi Tanya , Katz Ben , Michaeli Janna , Khawaled Saleh , Lev Shaya , Polyansky Lola , Shaul Merav E. , Sionov Ronit V. , Cohen-Daniel Leonor , Aqeilan Rami I. , Shaul Yoav D. , Mori Yasuo , Karni Rotem , Fridlender Zvi G. , Binshtok Alexander M. , Granot Zvi
Published: April 2023

Supplemental figure legends
Supplementary Tables S1 to S14 from Gene Expression Integration into Pathway Modules Reveals a Pan-Cancer Metabolic Landscape
Authors: Cubuk Cankut , Hidalgo Marta R. , Amadoz Alicia , Pujana Miguel A. , Mateo Francesca , Herranz Carmen , Carbonell-Caballero Jose , Dopazo Joaquin
Published: April 2023

Table S1: Cancer types. Table S2: Cell lines. Table S3: Metabolic modules. Table S4: Correlations between gene expression and RPPA values. Table S5: Correlation between the non-metabolic proteins and their corresponding gene expressions. Table S6: Fold changes of metabolites from metabolomics data and predicted module activities. Table S7: Subtype analysis. Table S8: Impact of mutations. Table S9: Modules whose activity is significantly associated to patient survival. Table S10: Combinations of module activities significantly related to patient survival. Table S11: Modules showing the strongest association with survival than any of their gene components. Table S12: Modules associated to different responses. Table S13: Validation of the effect of real Knock-Downs in genes. Table S14: Collection of drugs listed in drugbank with known targets within any of the modules used in this work.
Supplementary Figure S6 from mTOR Inhibition via Displacement of Phosphatidic Acid Induces Enhanced Cytotoxicity Specifically in Cancer Cells
Authors: Nguyen Tra-Ly , Nokin Marie-Julie , Egorov Maxim , Tomé Mercedes , Bodineau Clément , Di Primo Carmelo , Minder Lætitia , Wdzieczak-Bakala Joanna , Garcia-Alvarez Maria Concepcion , Bignon Jérôme , Thoison Odile , Delpech Bernard , Surpateanu Georgiana , Frapart Yves-Michel , Peyrot Fabienne , Abbas Kahina , Terés Silvia , Evrard Serge , Khatib Abdel-Majid , Soubeyran Pierre , Iorga Bogdan I. , Durán Raúl V. , Collin Pascal
Published: April 2023

The file contains supplementary results showing that inhibition of mTORC1 by ICSN3250 is responsible for its cytotoxicity in cancer cells.
Supplementary Figure S5 from mTOR Inhibition via Displacement of Phosphatidic Acid Induces Enhanced Cytotoxicity Specifically in Cancer Cells
Authors: Nguyen Tra-Ly , Nokin Marie-Julie , Egorov Maxim , Tomé Mercedes , Bodineau Clément , Di Primo Carmelo , Minder Lætitia , Wdzieczak-Bakala Joanna , Garcia-Alvarez Maria Concepcion , Bignon Jérôme , Thoison Odile , Delpech Bernard , Surpateanu Georgiana , Frapart Yves-Michel , Peyrot Fabienne , Abbas Kahina , Terés Silvia , Evrard Serge , Khatib Abdel-Majid , Soubeyran Pierre , Iorga Bogdan I. , Durán Raúl V. , Collin Pascal
Published: April 2023

The file contains supplementary results showing that ICSN3250 is redox inactive.
Supplementary Tables (Excel) from Whole-Genome Sequencing Reveals Elevated Tumor Mutational Burden and Initiating Driver Mutations in African Men with Treatment-Naïve, High-Risk Prostate Cancer
Authors: Jaratlerdsiri Weerachai , Chan Eva K.F. , Gong Tingting , Petersen Desiree C. , Kalsbeek Anton M.F. , Venter Philip A. , Stricker Phillip D. , Bornman M.S. Riana , Hayes Vanessa M.
Published: April 2023

Supplementary Excel Tables include Supplementary Table S5. Segmented copy number alterations in six African PCa patients identified by WGS. Supplementary Table S6. Clinical characteristics of previously published prostate tumors compared in this study. Supplementary Table S7. Allele distribution for known PCa risk alleles in SAPCS. Supplementary Table S9. Small somatic mutations in six African (SAPCS) and nine European (APCRC) patients with high-risk PCa. Supplementary Table S10. Oncogenic driver mutations in six African PCa patients. Supplementary Table S11. Somatic SVs in six African (SAPCS) and nine European (APCRC) patients with high-risk PCa. Supplementary Table S14. Machine learning prediction results of missense mutations (CanDrA program) showing potential oncogenic drivers in six African PCa patients and the impact of the drivers on cellular pathway alterations using PANTHER classification system. Supplementary Table S15. Recurrent SCNAs in six African PCa patients. Supplementary Table S16. Gene level copy number alterations in six African PCa patients. Columns 4 - 9 are absolute values and Columns 10 - 15 are relative values for percentage genome alteration, including 276 signature genes in Columns 16 - 19. Positive and negative values indicate gains and losses, respectively. Zero means neutral copy number variation.
Supplementary Information from YAP1-Mediated Suppression of USP31 Enhances NFκB Activity to Promote Sarcomagenesis
Authors: Ye Shuai , Lawlor Matthew A. , Rivera-Reyes Adrian , Egolf Shaun , Chor Susan , Pak Koreana , Ciotti Gabrielle E. , Lee Avery C. , Marino Gloria E. , Shah Jennifer , Niedzwicki David , Weber Kristy , Park Paul M.C. , Alam Md. Zahidul , Grazioli Alison , Haldar Malay , Xu Mousheng , Perry Jennifer A. , Qi Jun , Eisinger-Mathason T.S. Karin
Published: April 2023

Supplementary methods, references, and legends
Figure S7 from YAP1-Mediated Suppression of USP31 Enhances NFκB Activity to Promote Sarcomagenesis
Authors: Ye Shuai , Lawlor Matthew A. , Rivera-Reyes Adrian , Egolf Shaun , Chor Susan , Pak Koreana , Ciotti Gabrielle E. , Lee Avery C. , Marino Gloria E. , Shah Jennifer , Niedzwicki David , Weber Kristy , Park Paul M.C. , Alam Md. Zahidul , Grazioli Alison , Haldar Malay , Xu Mousheng , Perry Jennifer A. , Qi Jun , Eisinger-Mathason T.S. Karin
Published: April 2023

Supplemental Ingenuity Pathway Analysis and cleaved caspase 3 findings
Supplementary Tables from Targeting PARP1 in XRCC1-Deficient Sporadic Invasive Breast Cancer or Preinvasive Ductal Carcinoma In Situ Induces Synthetic Lethality and Chemoprevention
Authors: Ali Reem , Al-Kawaz Abdulbaqi , Toss Michael S. , Green Andrew R. , Miligy Islam M. , Mesquita Katia A. , Seedhouse Claire , Mirza Sameer , Band Vimla , Rakha Emad A , Madhusudan Srinivasan
Published: April 2023

Supplemental Table S1: Clinicopathological characteristics of whole breast cancer cohort Supplemental Table S2: Clinicopathological characteristics of ER- cohort Supplementary Table S3: Antigens, primary antibodies, clone, source, optimal dilution and scoring system used for each immunohistochemical marker Supplementary Table S4. Clinicopathological significance of PARP and XRCC1 co-expression in breast cancers. Supplementary Table S5: Percentage of cells in various stages of cell cycle. Supplementary Table S6: Patient demographics in DCIS cohort. Supplementary Table S7: XRCC1 and clinic-pathological associations in pure DCIS cohort Supplementary Table 8: List of EMT PCR array genes layout Supplementary Table S9: LD50 for PARP inhibitor sensitivity in XRCC1 deficient/knockout cells.
Table S2 from Pharmacologic Ascorbate Reduces Radiation-Induced Normal Tissue Toxicity and Enhances Tumor Radiosensitization in Pancreatic Cancer
Authors: Alexander Matthew S. , Wilkes Justin G. , Schroeder Samuel R. , Buettner Garry R. , Wagner Brett A. , Du Juan , Gibson-Corley Katherine , O’Leary Brianne R. , Spitz Douglas R. , Buatti John M. , Berg Daniel J. , Bodeker Kellie L. , Vollstedt Sandy , Brown Heather A. , Allen Bryan G. , Cullen Joseph J.
Published: April 2023

Additional Clinical Data for Comparator Patients.
Supplemental Material and Methods from Targeting CCR8 Induces Protective Antitumor Immunity and Enhances Vaccine-Induced Responses in Colon Cancer
Authors: Villarreal Daniel O. , L'Huillier Andrew , Armington Susan , Mottershead Cristina , Filippova Elena V. , Coder Brandon D. , Petit Robert G. , Princiotta Michael F.
Published: April 2023

File contains the supplementary Material and Methods
Supplemental Figures from Mcl-1 Phosphorylation without Degradation Mediates Sensitivity to HDAC Inhibitors by Liberating BH3-Only Proteins
Authors: Tong Jingshan , Zheng Xingnan , Tan Xiao , Fletcher Rochelle , Nikolovska-Coleska Zaneta , Yu Jian , Zhang Lin
Published: April 2023

Figure S1. HDACi promote GSK3β-mediated Mcl-1 phosphorylation, but not Mcl-1 degradation, in colon cancer cells. SAHA or MS-275 treatment did not affect Mcl-1 protein half-life in HCT116 cells, or induce Mcl-1 degradation in DLD1 and RKO cells. The 4A (S121A/E125A/S159A/T163A) mutant was more effective than WT Mcl-1 in suppressing SAHA- and MS-275-induced apoptosis in DLD1 and RKO cells. Figure S2. Knock-in of the 4A (S121A/E125A/S159A/T163A) mutant Mcl-1 suppressed apoptosis induced by HDACi and other anticancer agents. Figure S3. FBW7 was induced by the kinase inhibitors regorafenib and sorafenib, but not by the HDACi SAHA and MS-275 in colon cancer cells. Transfection of WT but not mutant FBW7 was sufficient to promote Mcl-1 degradation in cells treated with SAHA or MS-275. Figure S4. PUMA, Bim and Noxa mRNA was induced in HCT116 cells in response to SAHA and MS-275 treatment. Bim and Noxa were knocked out by homologous recombination in HCT116 cells. Figure S5. SAHA- and MS-275-induced apoptosis in HCT116 cells was suppressed by knockout of PUMA, Bim, Noxa or BAX. Figure S6. Immunoprecipitation analysis showed that the mutant Mcl-1 in the Mcl-1-KI cells had enhanced binding to Bim and Noxa in response to SAHA or MS-275 treatment. Figure S7. Mcl-1 inhibitors restored SAHA- and MS-275-induced apoptosis analyzed by annexin V/PI staining in Mcl-1-KI cells.
Figures S1-S5 and Tables S1-S3 from VEGFC Antibody Therapy Drives Differentiation of AML
Authors: Kampen Kim R. , Scherpen Frank J.G. , Mahmud Hasan , ter Elst Arja , Mulder André B. , Guryev Victor , Verhagen Han J.M.P. , De Keersmaecker Kim , Smit Linda , Kornblau Steven M. , De Bont Eveline S.J.M.
Published: April 2023

Complete supplementary Data file including supportive figures that highlight: VEGFC targeting potential in pediatric AML, VEGFC/KDR complex molecular targeting in AML, and VEGFC antibody induced differentiation phenotype in AML, and supplementary tables include the patient characteristics, used antibodies and primer sequences, and FLT3-ITD ratio's
Figure S2 from Reduced Expression of PROX1 Transitions Glioblastoma Cells into a Mesenchymal Gene Expression Subtype
Authors: Goudarzi Kaveh M. , Espinoza Jaime A. , Guo Min , Bartek Jiri , Nistér Monica , Lindström Mikael S. , Hägerstrand Daniel
Published: April 2023

Expression analysis of PROX1 in different glioma sample collections
Supplementary Data from A Novel Germline Variant in CSF3R Reduces N-Glycosylation and Exerts Potent Oncogenic Effects in Leukemia
Authors: Spiciarich David R. , Oh Stephen T. , Foley Amy , Hughes Seamus B. , Mauro Michael J. , Abdel-Wahab Omar , Press Richard D. , Viner Rosa , Thompson Sarah L. , Chen Qiushi , Azadi Parastoo , Bertozzi Carolyn R. , Maxson Julia E.
Published: April 2023

Supplemental Mass Spectrometry Methods including: MALDI-TOF MS analysis of released N-linked glycans, Protein Digestion for MS/MS analysis, and Glycoproteomics on TMT-labeled peptides
Figure S1 from Paclitaxel Reduces Tumor Growth by Reprogramming Tumor-Associated Macrophages to an M1 Profile in a TLR4-Dependent Manner
Authors: Wanderley Carlos W. , Colón David F. , Luiz João Paulo M. , Oliveira Francisco F. , Viacava Paula R. , Leite Caio A. , Pereira Janaina A. , Silva Camila M. , Silva Cassia R. , Silva Rangel L. , Speck-Hernandez Cesar A. , Mota José M. , Alves-Filho José C. , Lima-Junior Roberto C. , Cunha Thiago M. , Cunha Fernando Q.
Published: April 2023

PCX induces production of M1 markers in TLR2 deficient cells
Supplementary Figures S1-S12 and Supplementary Tables S1 and S3 from Loss of Pax5 Exploits Sca1-BCR-ABLp190 Susceptibility to Confer the Metabolic Shift Essential for pB-ALL
Authors: Martín-Lorenzo Alberto , Auer Franziska , Chan Lai N. , García-Ramírez Idoia , González-Herrero Inés , Rodríguez-Hernández Guillermo , Bartenhagen Christoph , Dugas Martin , Gombert Michael , Ginzel Sebastian , Blanco Oscar , Orfao Alberto , Alonso-López Diego , Rivas Javier De Las , García-Cenador Maria B. , García-Criado Francisco J. , Müschen Markus , Sánchez-García Isidro , Borkhardt Arndt , Vicente-Dueñas Carolina , Hauer Julia
Published: April 2023

Supplementary Figure 1: Mouse generation and GSEA enrichment analysis of Sca1-BCR-ABLp190 mice. Supplementary Figure 2: Time course of the percentage of B220+ cells in PB of Sca1-BCR-ABLp190 and Sca1-BCR-ABLp190+Pax5+/- mice. Supplementary figure 3: pB-ALL is transplantable to secondary recipients. Supplementary figure 4: Sca1-BCR-ABLp190+Pax5+/- mice housed in SPF develop similar pB-ALL than Sca1-BCR-ABLp190+Pax5+/- mice housed in CF Supplementary Figure 5: transcriptome analysis of Sca1-BCR-ABLp190+Pax5+/- mice. Supplementary Figure 6: Mouse tumor exome sequencing data identified recurrent Pax5 mutations. Supplementary Figure 7: Polyclonal VDJ recombination events in pre-leukemic B220-positive cells from the BM of Sca1-BCR-ABLp190+Pax5+/- mice Supplementary Figure 8: Altered pathways in leukemic Sca1-BCR-ABLp190+Pax5+/-. Supplementary Figure 9: Quantitative differences of mRNA levels of glycolytic related genes between leukemic Sca1-BCR-ABLp190+Pax5+/-, Sca1-BCR-ABLp190 and wild-type B cells. Supplementary Figure 10: QRT-PCR validation of microarray data. Supplementary Figure 11: Metabolic signature in human pB-ALLs. Supplementary Figure 12: Analysis of ChIP-seq data revealed novel targets of PAX5 in human B lymphocytes. Supplementary Table 1: Percentage and total numbers of hematopoietic progenitor compartments in young Sca1-BCR-ABLp190 and wild type mice. Supplementary Table 3: pB-ALL genotype and phenotype of Sca1-BCR-ABLp190+Pax5+/- and Sca1-BCR-ABLp190 mice.
Supplementary Figures S1-S11 from Targeting STAT5 or STAT5-Regulated Pathways Suppresses Leukemogenesis of Ph+ Acute Lymphoblastic Leukemia
Authors: Minieri Valentina , De Dominici Marco , Porazzi Patrizia , Mariani Samanta A. , Spinelli Orietta , Rambaldi Alessandro , Peterson Luke F. , Porcu Pierluigi , Nevalainen Marja T. , Calabretta Bruno
Published: April 2023

Supplementary Fig. S1. Effect of Doxycycline on shScramble (shSCR)-transduced Ph+ ALL cell lines. Supplementary Fig. S2. Effect of STAT5 inhibitor IST5-002 on Ph+ leukemia lines. Supplementary Fig. S3. Effect of treatment with IST5-002 in Ph like leukemia cells. Supplementary Fig. S4. Effect of IST5-002 on G-CSF-mobilized peripheral blood normal CD34+ hematopoietic cells. Supplementary Fig. S5. Effect of BIM silencing on apoptosis of STAT5-silenced Ph+ ALL cells. Supplementary Fig. S6. qPCR analysis of STAT5-regulated genes in untreated and Doxy-treated shScramble- or shSTAT5-BV173 cells. Supplementary Fig. S7. Levels of PIM1-s in STAT5-silenced Ph+ ALL lines and correlation with STAT5 expression in primary Ph+ ALL cells. Supplementary Fig. S8. Ectopic expression of PIM-1 does not rescue the apoptosis of STAT5-silenced BV173 cells. Supplementary Fig. S9. Effect of AZD1208 and Sabutoclax on cell growth and survival of Ph+ leukemia cell lines. Supplementary Fig. S10. Effects of the AZD1208- Sabutoclax combination on the growth of Ph+ leukemia cell lines. Supplementary Fig. S11. Effects of the AZD1208, Sabutoclax, or the drug combination on colony formation of Ph-like cell lines.
Supplementary Materials and Methods from YAP/TAZ Initiates Gastric Tumorigenesis via Upregulation of MYC
Authors: Choi Wonyoung , Kim Jeongsik , Park Jaeoh , Lee Da-Hye , Hwang Daehee , Kim Jeong-Hwan , Ashktorab Hassan , Smoot Duane , Kim Seon-Young , Choi Chan , Koh Gou Young , Lim Dae-Sik
Published: April 2023

Supplementary Materials and Methods
Table S1 from RIPK1 Binds MCU to Mediate Induction of Mitochondrial Ca2+ Uptake and Promotes Colorectal Oncogenesis
Authors: Zeng Fanxin , Chen Xiao , Cui Weiyi , Wen Wei , Lu Fujian , Sun Xueting , Ma Dongwei , Yuan Ye , Li Zezhong , Hou Ning , Zhao Hong , Bi Xinyu , Zhao Jianjun , Zhou Jianguo , Zhang Yan , Xiao Rui-Ping , Cai Jianqiang , Zhang Xiuqin
Published: April 2023

Table S1 shows the patients information in CRC.
Supplemental Table from HLA Class I and II Diversity Contributes to the Etiologic Heterogeneity of Non-Hodgkin Lymphoma Subtypes
Authors: Wang Sophia S. , Carrington Mary , Berndt Sonja I. , Slager Susan L. , Bracci Paige M. , Voutsinas Jenna , Cerhan James R. , Smedby Karin E. , Hjalgrim Henrik , Vijai Joseph , Morton Lindsay M. , Vermeulen Roel , Paltiel Ora , Vajdic Claire M. , Linet Martha S. , Nieters Alexandra , de Sanjose Silvia , Cozen Wendy , Brown Elizabeth E. , Turner Jennifer , Spinelli John J. , Zheng Tongzhang , Birmann Brenda M. , Flowers Christopher R. , Becker Nikolaus , Holly Elizabeth A. , Kane Eleanor , Weisenburger Dennis , Maynadie Marc , Cocco Pierluigi , Albanes Demetrius , Weinstein Stephanie J. , Teras Lauren R. , Diver W. Ryan , Lax Stephanie J. , Travis Ruth C. , Kaaks Rudolph , Riboli Elio , Benavente Yolanda , Brennan Paul , McKay James , Delfau-Larue Marie-Hélène , Link Brian K. , Magnani Corrado , Ennas Maria Grazia , Latte Giancarlo , Feldman Andrew L. , Doo Nicole Wong , Giles Graham G. , Southey Melissa C. , Milne Roger L. , Offit Kenneth , Musinsky Jacob , Arslan Alan A. , Purdue Mark P. , Adami Hans-Olov , Melbye Mads , Glimelius Bengt , Conde Lucia , Camp Nicola J. , Glenn Martha , Curtin Karen , Clavel Jacqueline , Monnereau Alain , Cox David G. , Ghesquières Hervé , Salles Gilles , Bofetta Paulo , Foretova Lenka , Staines Anthony , Davis Scott , Severson Richard K. , Lan Qing , Brooks-Wilson Angela , Smith Martyn T. , Roman Eve , Kricker Anne , Zhang Yawei , Kraft Peter , Chanock Stephen J. , Rothman Nathaniel , Hartge Patricia , Skibola Christine F.
Published: April 2023

SUPPLEMENTAL TABLE: Effect of homozygosity at the three HLA class I loci -A, -B and -C and five HLA class I loci -DRB1, DQA1, DQB1, DPA1, and DPB1 on susceptibility to four NHL subtypes (DLBCL, FL, CLL/SLL, and MZL) stratified by GWAS platform (analyses adjusted for sex, age, and ancestry/principal components)
Supplementary Data from Fibrin Stiffness Mediates Dormancy of Tumor-Repopulating Cells via a Cdc42-Driven Tet2 Epigenetic Program
Authors: Liu Yuying , Lv Jiadi , Liang Xiaoyu , Yin Xiaonan , Zhang Le , Chen Degao , Jin Xun , Fiskesund Roland , Tang Ke , Ma Jingwei , Zhang Huafeng , Dong Wenqian , Mo Siqi , Zhang Tianzhen , Cheng Feiran , Zhou Yabo , Xie Jing , Wang Ning , Huang Bo
Published: April 2023

Figure S1 related to figure 1; figure S2 related to figure 2; figure S3 related to figure 3; figure S4 related to figure 4; figure S5 related to figure 5; figure S6 related to figure 6 and supplementary experimental procedures
Figure S3 from Zika Virus Selectively Kills Aggressive Human Embryonal CNS Tumor Cells In Vitro and In Vivo
Authors: Kaid Carolini , Goulart Ernesto , Caires-Júnior Luiz C. , Araujo Bruno H.S. , Soares-Schanoski Alessandra , Bueno Heloisa M.S. , Telles-Silva Kayque A. , Astray Renato M. , Assoni Amanda F. , Júnior Antônio F.R. , Ventini Daniella C. , Puglia Ana L.P. , Gomes Roselane P. , Zatz Mayana , Okamoto Oswaldo K.
Published: April 2023

Oncolytic assessment of ZIKVBR in mice bearing orthotopically implanted tumors.
Figure S3 from Astrocyte Elevated Gene-1 Regulates Macrophage Activation in Hepatocellular Carcinogenesis
Authors: Robertson Chadia L. , Mendoza Rachel G. , Jariwala Nidhi , Dozmorov Mikhail , Mukhopadhyay Nitai D. , Subler Mark A. , Windle Jolene J. , Lai Zhao , Fisher Paul B. , Ghosh Shobha , Sarkar Devanand
Published: April 2023

This figure shows low magnification images of liver sections in DEN/PB-treated mice.
Supplementary Figure 5 from CRISPR/Cas9-Mediated Knockout of DGK Improves Antitumor Activities of Human T Cells
Authors: Jung In-Young , Kim Yoon-Young , Yu Ho-Sung , Lee Myoungsoo , Kim Seokjoong , Lee Jungmin
Published: April 2023

139 CAR-T cells upregulate PD-1 expression after co-incubation with U87vIII.
Supplementary Figure 2 from CRISPR/Cas9-Mediated Knockout of DGK Improves Antitumor Activities of Human T Cells
Authors: Jung In-Young , Kim Yoon-Young , Yu Ho-Sung , Lee Myoungsoo , Kim Seokjoong , Lee Jungmin
Published: April 2023

An optimized CRISPR/Cas9-mediated DGK KO process achieved high KO efficiency while maintaining cell growth and viability of T cells.
Supplementary Table 1 from CAMKK2 Promotes Prostate Cancer Independently of AMPK via Increased Lipogenesis
Authors: Penfold Lucy , Woods Angela , Muckett Phillip , Nikitin Alexander Yu. , Kent Tera R. , Zhang Shuai , Graham Rebecca , Pollard Alice , Carling David
Published: April 2023

Primers used in this study.
Table S2, Table S3 from Transcriptomic Differences between Primary Colorectal Adenocarcinomas and Distant Metastases Reveal Metastatic Colorectal Cancer Subtypes
Authors: Kamal Yasmin , Schmit Stephanie L. , Hoehn Hannah J. , Amos Christopher I. , Frost H. Robert
Published: April 2023

Table S2. Extended Table 2 for MCC dataset: Determining differences between primary colorectal adenocarcinomas and liver metastases with (tissue sensitive) and without (tissue agnostic) consideration of tissue-specific pathway expression: Hallmark and C2 Collection. Table S3. Extended Table 2 for MCC dataset: Determining differences between primary colorectal adenocarcinomas and lung metastases with (tissue sensitive) and without (tissue agnostic) consideration of tissue-specific pathway expression: Hallmark and C2 Collection
Supplementary Figures from Inhibition of Thioredoxin/Thioredoxin Reductase Induces Synthetic Lethality in Lung Cancers with Compromised Glutathione Homeostasis
Authors: Yan Xiang , Zhang Xiaoshan , Wang Li , Zhang Ran , Pu Xingxiang , Wu Shuhong , Li Lei , Tong Pan , Wang Jing , Meng Qing H. , Jensen Vanessa B. , Girard Luc , Minna John D. , Roth Jack A. , Swisher Stephen G. , Heymach John V. , Fang Bingliang
Published: April 2023

Figure S1 shows dose-response curves of aurothioglucose in A549 and A549/GSR-/- cells. Figure S2 shows Western blot analysis of GSR and responses to auranofin treatment in H1993 cells after transfection with GSR expression vector or control vector.
Figure S7 from Poly (ADP) Ribose Glycohydrolase Can Be Effectively Targeted in Pancreatic Cancer
Authors: Jain Aditi , Agostini Lebaron C. , McCarthy Grace A. , Chand Saswati N. , Ramirez AnnJosette , Nevler Avinoam , Cozzitorto Joseph , Schultz Christopher W. , Lowder Cinthya Yabar , Smith Kate M. , Waddell Ian D. , Raitses-Gurevich Maria , Stossel Chani , Gorman Yulia Glick , Atias Dikla , Yeo Charles J. , Winter Jordan M. , Olive Kenneth P. , Golan Talia , Pishvaian Michael J. , Ogilvie Donald , James Dominic I. , Jordan Allan M. , Brody Jonathan R.
Published: April 2023

Supplementary Fig S7 describes western blot and RTPCR of PARG in modified shPARG cells.
Figure S1 from CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms
Authors: Castillo Joseph , Wu Esther , Lowe Christopher , Srinivasan Shrividhya , McCord Ron , Wagle Marie-Claire , Jayakar Sangeeta , Edick Melissa Gonzalez , Eastham-Anderson Jeffrey , Liu Bonnie , Hutchinson Katherine E. , Jones Wendell , Stokes Matthew P. , Tarighat Somayeh S. , Holcomb Thomas , Glibicky Andrew , Romero F. Anthony , Magnuson Steven , Huang Shih-Min A. , Plaks Vicki , Giltnane Jennifer M. , Lackner Mark R. , Mounir Zineb
Published: April 2023

Supplementary figure 1 shows supportive RT-qPCR data on the transcriptional modulation of Treg differentiation by CBP/p300 along with the proliferation effects of CBP/p300 inhibitor GNE-781 on T cells and Tregs.
Figure S1 from Poly (ADP) Ribose Glycohydrolase Can Be Effectively Targeted in Pancreatic Cancer
Authors: Jain Aditi , Agostini Lebaron C. , McCarthy Grace A. , Chand Saswati N. , Ramirez AnnJosette , Nevler Avinoam , Cozzitorto Joseph , Schultz Christopher W. , Lowder Cinthya Yabar , Smith Kate M. , Waddell Ian D. , Raitses-Gurevich Maria , Stossel Chani , Gorman Yulia Glick , Atias Dikla , Yeo Charles J. , Winter Jordan M. , Olive Kenneth P. , Golan Talia , Pishvaian Michael J. , Ogilvie Donald , James Dominic I. , Jordan Allan M. , Brody Jonathan R.
Published: April 2023

Supplementary Figure S1 describes mRNA and protein expression of PARG in shPARG models and in vitro sensitivity to oxaliplatin.
Figure S6 from Remodeling the Tumor Microenvironment Sensitizes Breast Tumors to Anti-Programmed Death-Ligand 1 Immunotherapy
Authors: Clift Renee , Souratha Jennifer , Garrovillo Sheryl A. , Zimmerman Susan , Blouw Barbara
Published: April 2023

Pegvorhyaluronidase alfa in combination with anti-PD-L1 effect on density of T-cells and NK cells and the proportion of Gr1+ myeloid-derived suppressor cells in EMT-6 orthotopic breast tumors
Supplementary Data from A Direct Podocalyxin–Dynamin-2 Interaction Regulates Cytoskeletal Dynamics to Promote Migration and Metastasis in Pancreatic Cancer Cells
Authors: Wong Bin Sheng , Shea Daniel J. , Mistriotis Panagiotis , Tuntithavornwat Soontorn , Law Robert A. , Bieber Jake M. , Zheng Lei , Konstantopoulos Konstantinos
Published: April 2023

Contains Supplementary Figures, Supplementary Figure Legends, Supplementary Video Legends, Supplementary Table and Supplementary Methods
Figure S1 from Remodeling the Tumor Microenvironment Sensitizes Breast Tumors to Anti-Programmed Death-Ligand 1 Immunotherapy
Authors: Clift Renee , Souratha Jennifer , Garrovillo Sheryl A. , Zimmerman Susan , Blouw Barbara
Published: April 2023

Tumor growth in 4T1 and 4T1/HAS3 tumors
Microfluidics chip based exosome proteomic profiling from A Microfluidic Chip Enables Isolation of Exosomes and Establishment of Their Protein Profiles and Associated Signaling Pathways in Ovarian Cancer
Authors: Dorayappan Kalpana Deepa Priya , Gardner Miranda L. , Hisey Colin L. , Zingarelli Roman A. , Smith Brentley Q. , Lightfoot Michelle D.S. , Gogna Rajan , Flannery Meghan M. , Hays John , Hansford Derek J. , Freitas Michael A. , Yu Lianbo , Cohn David E. , Selvendiran Karuppaiyah
Published: April 2023

Sup. Tables: S1-S3 is Gene Ontology Term analysis by Panther db in cancer cells Vs normal cells. S4-S6 is IPA core analysis showing the top protein molecules identified to be upregulated in cancer cells Vs normal cells. S7 is Proximity Extension Assay for select the Immuno-oncology panel proteins that were significantly higher in HGSOC
Supplementary Figure 2 from Gene Editing of α6 Integrin Inhibits Muscle Invasive Networks and Increases Cell–Cell Biophysical Properties in Prostate Cancer
Authors: Rubenstein Cynthia S. , Gard Jaime M.C. , Wang Mengdie , McGrath Julie E. , Ingabire Nadia , Hinton James P. , Marr Kendra D. , Simpson Skyler J. , Nagle Raymond B. , Miranti Cindy K. , Warfel Noel A. , Garcia Joe G.N. , Arif-Tiwari Hina , Cress Anne E.
Published: April 2023

Prostate 3D cell networks require expression of integrin α6, FAK, and uPAR
Supplementary Table S1 from Deletion of the Miz-1 POZ Domain Increases Efficacy of Cytarabine Treatment in T- and B-ALL/Lymphoma Mouse Models
Authors: Ross Julie , Rashkovan Marissa , Fraszczak Jennifer , Joly-Beauparlant Charles , Vadnais Charles , Winkler René , Droit Arnaud , Kosan Christian , Möröy Tarik
Published: April 2023

GSEA KEGG and reactome
Supplementary Data from Deletion of the Miz-1 POZ Domain Increases Efficacy of Cytarabine Treatment in T- and B-ALL/Lymphoma Mouse Models
Authors: Ross Julie , Rashkovan Marissa , Fraszczak Jennifer , Joly-Beauparlant Charles , Vadnais Charles , Winkler René , Droit Arnaud , Kosan Christian , Möröy Tarik
Published: April 2023

Supplementary Figures + Supplementary Materials and Methods
Supplementary Data from HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy
Authors: Emmons Michael F. , Faião-Flores Fernanda , Sharma Ritin , Thapa Ram , Messina Jane L. , Becker Jurgen C. , Schadendorf Dirk , Seto Edward , Sondak Vernon K. , Koomen John M. , Chen Yian A. , Lau Eric K. , Wan Lixin , Licht Jonathan D. , Smalley Keiran S.M.
Published: April 2023

Supplementary Table 1: Clinical data on samples stained for HDAC8 expression. S1) HDAC expression levels in melanoma cells S2) Cell lines that are resistant to BRAF inhibitors have upregulated c-Jun protein expression S3) Inhibiting HDAC6 does not resensitize BRAF/MEK resistant cells to BRAF inhibitors S4) BRAF/MEK inhibitor withdrawal decreases HDAC8 expression over time S5) Knocking down or elevating HDAC8 levels does not change cell proliferation S6) Expression of HDAC8 increased ERK activity and resistance upon treatment with BRAF-MEK inhibitors S7) Knocking down HDAC8 in BRAFi naïve cells increased apoptosis and BIM expression while decreasing ERK activity after BRAFi activity. S8) HDAC8 expression increases baseline RTK signaling S9) Inhibiting MET or FGFR3 partially resensitizes HDAC8 expressing cells to BRAF inhibitors S10) HDAC8 expression increases baseline c-Jun, p53, AKT and HSP60 signaling S11) Inhibiting c-Jun resensitizes HDAC8 expressing cells to a BRAF inhibitor S12) Protein sequences of c-Jun acetyl mutants S13) Acetylation-deficient c-JUN at residue 273 increases melanoma cell survival following BRAF inhibition S14) Acetylation-deficient c-Jun at residue 273 increases p53, Akt 1/2/3, STAT3, WNK1 and HSP60 S15) Acetylation-deficient c-JUN at residue 273 increases baseline EGFR signaling
Table S4 from Epigenetic Regulation of NAMPT by NAMPT-ASDrives Metastatic Progression in Triple-Negative Breast Cancer
Authors: Zhang Hanwen , Zhang Ning , Liu Ying , Su Peng , Liang Yiran , Li Yaming , Wang Xiaolong , Chen Tong , Song Xiaojin , Sang Yuting , Duan Yi , Zhang Jiashu , Wang Lijuan , Chen Bing , Zhao Wenjing , Guo Haiyang , Liu Zhaojian , Hu Guohong , Yang Qifeng
Published: April 2023

Univariate cox analysis of overall survival and relapse-free survival in TCGA breast cancer patients
Table S3 from Epigenetic Regulation of NAMPT by NAMPT-ASDrives Metastatic Progression in Triple-Negative Breast Cancer
Authors: Zhang Hanwen , Zhang Ning , Liu Ying , Su Peng , Liang Yiran , Li Yaming , Wang Xiaolong , Chen Tong , Song Xiaojin , Sang Yuting , Duan Yi , Zhang Jiashu , Wang Lijuan , Chen Bing , Zhao Wenjing , Guo Haiyang , Liu Zhaojian , Hu Guohong , Yang Qifeng
Published: April 2023

Associations between NAMPT-AS level and clinico-pathological characteristics in TCGA breast cancer patients
Figure S1 from LINE-1 Retrotransposition Promotes the Development and Progression of Lung Squamous Cell Carcinoma by Disrupting the Tumor-Suppressor Gene FGGY
Authors: Zhang Rui , Zhang Fan , Sun Zeguo , Liu Pengpeng , Zhang Xiao , Ye Yingnan , Cai Beiqi , Walsh Martin J. , Ren Xiubao , Hao Xishan , Zhang Weijia , Yu Jinpu
Published: April 2023

LINE-1 RTs were validated in cell lines.
Table S2 from Epigenetic Regulation of NAMPT by NAMPT-ASDrives Metastatic Progression in Triple-Negative Breast Cancer
Authors: Zhang Hanwen , Zhang Ning , Liu Ying , Su Peng , Liang Yiran , Li Yaming , Wang Xiaolong , Chen Tong , Song Xiaojin , Sang Yuting , Duan Yi , Zhang Jiashu , Wang Lijuan , Chen Bing , Zhao Wenjing , Guo Haiyang , Liu Zhaojian , Hu Guohong , Yang Qifeng
Published: April 2023

Antibody information
Supplementary Tables S1-S5 from Epigenomic Reordering Induced by Polycomb Loss Drives Oncogenesis but Leads to Therapeutic Vulnerabilities in Malignant Peripheral Nerve Sheath Tumors
Authors: Wojcik John B. , Marchione Dylan M. , Sidoli Simone , Djedid Anissa , Lisby Amanda , Majewski Jacek , Garcia Benjamin A.
Published: April 2023

Tabbed excel spreadsheet with each tab representing a single supplementary table. The first cell of each tab contains a description of the contents. Supplemental Table 1: Log2 normalized protein abundances of proteins identified in FFPE MPNST samples. Supplemental Table 2: GO term enrichment for proteins showing increased levels with PRC2 loss. Supplemental Table 3: GO term enrichment for proteins showing decreased levels with PRC2 loss. Supplemental Table 4: GO term enrichment for proteins showing increased levels following both SUZ12 restoration and NSD2 knockdown. Supplemental Table 5: GO term enrichment for proteins showing increased levels following decitabine treatment.
Supplementary Data Legends from Epigenomic Reordering Induced by Polycomb Loss Drives Oncogenesis but Leads to Therapeutic Vulnerabilities in Malignant Peripheral Nerve Sheath Tumors
Authors: Wojcik John B. , Marchione Dylan M. , Sidoli Simone , Djedid Anissa , Lisby Amanda , Majewski Jacek , Garcia Benjamin A.
Published: April 2023

Word file containing legends for supplemental figures S1-S4 and Supplemental tables 1-5
Supplementary Figure 7 from 2-Hydroxyglutarate-Mediated Autophagy of the Endoplasmic Reticulum Leads to an Unusual Downregulation of Phospholipid Biosynthesis in Mutant IDH1 Gliomas
Authors: Viswanath Pavithra , Radoul Marina , Izquierdo-Garcia Jose Luis , Ong Wei Qiang , Luchman Hema Artee , Cairncross J. Gregory , Huang Bo , Pieper Russell O. , Phillips Joanna J. , Ronen Sabrina M.
Published: April 2023

CQ and BAF do not affect ER area or phospholipid levels in IDHwt glioma cells.
Supplementary Figure 4 from 2-Hydroxyglutarate-Mediated Autophagy of the Endoplasmic Reticulum Leads to an Unusual Downregulation of Phospholipid Biosynthesis in Mutant IDH1 Gliomas
Authors: Viswanath Pavithra , Radoul Marina , Izquierdo-Garcia Jose Luis , Ong Wei Qiang , Luchman Hema Artee , Cairncross J. Gregory , Huang Bo , Pieper Russell O. , Phillips Joanna J. , Ronen Sabrina M.
Published: April 2023

2-HG induces ER-phagy in IDHmut glioma cells.
Movie S4 from A Human Organotypic Microfluidic Tumor Model Permits Investigation of the Interplay between Patient-Derived Fibroblasts and Breast Cancer Cells
Authors: Truong Danh D. , Kratz Alexander , Park Jin G. , Barrientos Eric S. , Saini Harpinder , Nguyen Toan , Pockaj Barbara , Mouneimne Ghassan , LaBaer Joshua , Nikkhah Mehdi
Published: April 2023

Time-lapse imaging of CAFs migrating through the 3D stroma in presence of SUM-159 breast cancer cells.
Figure S1 from The Transcriptional Regulator Sin3A Contributes to the Oncogenic Potential of STAT3
Authors: Gambi Giovanni , Di Simone Elisabetta , Basso Veronica , Ricci Luisa , Wang Rui , Verma Akanksha , Elemento Olivier , Ponzoni Maurilio , Inghirami Giorgio , Icardi Laura , Mondino Anna
Published: April 2023

Data depict STAT3 phosphorylation and acetylation in NPM-ALK+ ALCL
Supplementary Table S2 from HER2 Overexpression Triggers an IL1α Proinflammatory Circuit to Drive Tumorigenesis and Promote Chemotherapy Resistance
Authors: Liu Shou , Lee Ji Shin , Jie Chunfa , Park Min Ho , Iwakura Yoichiro , Patel Yogin , Soni Mithil , Reisman David , Chen Hexin
Published: April 2023

Supplementary Table S2 shows the clinicopathological characteristics of clinical samples.
Supplementary Data from The HPV16 Genome Is Stable in Women Who Progress to In Situ or Invasive Cervical Cancer: A Prospective Population-Based Study
Authors: Arroyo-Mühr Laila-Sara , Lagheden Camilla , Hultin Emilie , Eklund Carina , Adami Hans-Olov , Dillner Joakim , Sundström Karin
Published: April 2023

Supplementary Table 1: Nucleotide variant calls detected over time in pairs of serial cervical smears from 94 women.
Figure S1 from SIX2 Mediates Late-Stage Metastasis via Direct Regulation of SOX2 and Induction of a Cancer Stem Cell Program
Authors: Oliphant Michael U.J. , Vincent Melanie Y. , Galbraith Matthew D. , Pandey Ahwan , Zaberezhnyy Vadym , Rudra Pratyaydipta , Johnson Katherine R. , Costello James C. , Ghosh Debashis , DeGregori James , Espinosa Joaquin M. , Ford Heide L.
Published: April 2023

Levels of Six2 OE in 4T07 cells is comparable to levels in multiple other human TNBC cell lines with relatively high endogenous Six2 expression.