bluuebunny/crossref_metadata_2025 huggingface dataset:
Correlation between placental weight and birth weight of the newborn and its effect on perinatal outcome: a hospital based cross-sectional study
Authors: Inamdar Shanti Sampada S. , Kuntoji Nagarathna G. , Mallapur Ashalatha , Mural Prabhu Hanamantappa
Published: February 2025

Background: The placental weight and its correlation with birth weight have been studied extensively for their potential associations with fetal growth and perinatal outcomes. This study aimed to investigate the correlation between placental weight and birth weight of newborns and evaluate the effects of this correlation on perinatal outcomes.
Methods: This hospital-based cross-sectional study included 50 pregnant women with singleton pregnancies without comorbidities. Placental weight was measured immediately after delivery, and birth weight was recorded within the first hour. Perinatal outcomes such as Apgar scores, neonatal intensive care unit (NICU) admission, and respiratory distress were documented. Statistical analysis included descriptive statistics, Pearson's correlation coefficient, and appropriate tests to analyze the effects of placental weight and birth weight on perinatal outcomes.
Results: A positive correlation was observed between placental weight and birth weight of newborns. No significant differences were found in mean birth weight and placental weight across gestational age groups. Lower birth weights and placental weights were associated with adverse perinatal outcomes, including lower Apgar scores, increased NICU admissions, and higher incidence of respiratory distress.
Conclusions: The positive correlation between placental weight and birth weight reinforces the crucial role of the placenta in supporting fetal growth and development. Deviations from normal placental weight may signal underlying placental insufficiency or pathological conditions, increasing the risk of adverse perinatal events. Monitoring placental weight and fetal growth during pregnancy may help identify high-risk pregnancies and optimize perinatal outcomes.
Ectopic pregnancy: an analysis of risk factors, diagnosis and management
Authors: Manohar Navya , Ramanujam Sai Latha
Published: February 2025

Background: Ectopic pregnancy (EP), implantation outside the uterine cavity, is a leading cause of first-trimester maternal morbidity and mortality. Tubal pregnancies constitute over 90% of cases, with risk factors including pelvic inflammatory disease (PID), assisted reproductive technologies (ART), and delayed childbearing. Advances in transvaginal ultrasonography and β-hCG assays have improved early detection, but challenges in diagnosis and management persist. This study examines trends, risk factors, and management outcomes of EP at Chettinad medical college, Kelambakkam.
Methods: A retrospective, non-interventional study of 50 EP cases (Jan 2023-June 2024) analyzed patient demographics, clinical presentations, and treatment outcomes. Descriptive and inferential statistics (Chi-square test, p<0.05) were used for analysis via SPSS.
Results: The mean age was 29.02 years (23-35). Abdominal pain (13 cases) was the most frequent symptom, followed by the classic triad (12 cases). Prior EP (13 cases), PID, and ART were primary risk factors. Unruptured EPs (17 right, 12 left) were more common. Medical management (19 cases) was initially used, but 15 required surgery post-failure. No significant correlation was found between risk factors and symptoms (Chi-square=57.64, p=0.85).
Conclusions: EP predominantly affects reproductive-age women, with abdominal pain as the primary symptom and prior EP as the main risk factor. Diagnostic advancements improve outcomes, but challenges remain in optimizing medical management and recurrence prevention. Future research should refine diagnostic markers and treatment strategies to reduce morbidity and mortality.
An approach to reduce labor pain and increase vaginal birth rate
Authors: Gangwar Archana , Gupta Sudhir
Published: February 2025

Background: Labor pain is considered one of the most intense pains experienced by women. Effective pain management is crucial in enhancing maternal satisfaction and ensuring a positive childbirth experience. The peri-pudendal block (PPB) is a promising alternative to conventional pain management strategies during the second stage of labor. This study evaluated the efficacy of the peri-pudendal block in reducing labor pain, episiotomy rates, and improving maternal and neonatal outcomes.
Methods: A prospective randomized controlled trial was conducted at BRD Medical College, Gorakhpur, involving 206 women with term pregnancies. Participants were divided into two groups: those receiving PPB (n=107) and those receiving standard care (n=99). Visual analogue scale (VAS) scores, duration of the second stage of labor, episiotomy rates, perineal injuries, and neonatal outcomes (APGAR scores) were assessed.
Results: PPB significantly reduced VAS scores in both primiparous and multiparous women (4.61±0.12 and 4.36±0.78, respectively). The second stage of labor was shorter in the PPB group for both primiparous (51.52±5.80 minutes) and multiparous women (24.49±4.23 minutes). Episiotomy rates were significantly lower in the PPB group (63% for primiparous and 26.4% for multiparous women). No significant differences in neonatal APGAR scores or maternal cardiovascular parameters were observed.
Conclusions: The peri-pudendal block is a safe and effective analgesic option during labor, improving maternal comfort and reducing surgical interventions without compromising neonatal outcomes.
The role of levonorgestrel intrauterine device in managing abnormal uterine bleeding
Authors: Shree J. Raveena , Sailatha
Published: February 2025

Background: Abnormal uterine bleeding (AUB) is a prevalent gynecological condition affecting menstrual regularity and quality of life, with causes ranging from structural abnormalities to hormonal imbalances. Conventional treatments, including hormonal therapy and surgery, pose challenges such as side effects, non-compliance, and fertility loss. The levonorgestrel-releasing intrauterine device (LNG-IUD) offers a minimally invasive alternative, targeting the endometrium to reduce menstrual blood loss while minimizing systemic effects.
Methods: This study evaluated the efficacy, safety, and acceptability of LNG-IUD in 52 women with AUB over 24 months. Clinical outcomes, including bleeding patterns, USG findings, complications, and satisfaction, were assessed at baseline and follow-ups (1 week, 1 month, and 6 months). Statistical analysis was conducted using SPSS v25.0.
Results: The mean age was 42.8 years, with menorrhagia (55.8%) being the most common complaint. Adenomyosis (38.5%) and thickened endometrium (30.8%) were frequent sonographic findings. At 6 months, 48% achieved amenorrhea, and spotting decreased to 36.5%. LNG-IUD retention was 88.4%, with removal in 7.6% and expulsion in 3.8%. Treatment failures led to hysterectomy (7.6%) and hormonal therapy (3.8%). Patient satisfaction was high, with 63.5% reporting being satisfied.
Conclusions: LNG-IUD proved highly effective, safe, and well-accepted for AUB management, significantly reducing menstrual blood loss and improving patient outcomes. Its high retention and satisfaction rates make it a viable alternative to systemic hormonal therapy and surgery, particularly for those seeking uterine preservation. Further studies should explore its long-term efficacy across AUB subtypes.
A case report of uterine leiomyosarcoma
Authors: Kirubanandan Sandhiya , Jaget Nirmala , Sekar Sindhuja , Saranya Sri , R. Priyanka
Published: February 2025

The most prevalent benign tumour in women is uterine leiomyoma. Smooth muscle cells give rise to the uncommon malignant tumour known as uterine leiomyosarcoma. It makes up 1% of all uterine cancers. One out of every 800 women who are thought to have leiomyoma actually has a sarcoma. Uterine leiomyosarcoma is usually diagnosed by histopathological examination and surgery is the only treatment. We describe a 48-year-old woman who had heavy menstrual flow and was initially diagnosed with uterine leiomyoma. Histological analysis revealed that she actually had uterine leiomyosarcoma.
Prevailing circumstances governing abortion in Africa
Authors: Unnithan Vishnu B. , Shree S. Lalitha Lavanya , O. Uzoka Favour , Shrinivas Divya , Singh Shivangi
Published: February 2025

A woman's worth is closely tied to childbirth in many African societies. The immense cultural emphasis that is placed on pregnancy means that women are also subject to stigmatization in the event of unintended pregnancies. In the patriarchal societies that commonly make up the region, a woman’s bodily autonomy is often subjugated to insensitive decisions taken by men based on social circumstances.  Abortion remains a largely taboo topic with the resulting lack of informed awareness putting women at risk. The current review aims to change that discourse by examining the sociodemographic considerations, beliefs, and traditions across various regions that prevent the effective utilization of existing facilities. The risk factors that govern elective abortions are examined with attention being given to commonly found age-disparate relationships as well as vulnerable and marginalized sections of society. The impact of the pandemic is also discussed with recommendations on multi-level action plans that would allow for effective advocacy. There is a lack of access to safe abortion infrastructure. Strengthening healthcare delivery infrastructure will mitigate the national economic burden and ensure that female reproductive health receives the attention it deserves.
Chronic pelvic pain: a comprehensive review on its physical and mental effects
Authors: Mohapatra Ipsita , Samantaray Subha Ranjan
Published: February 2025

Chronic pelvic pain (CPP) is a multifaceted and often debilitating condition that affects a significant portion of the female population wherein there is persistent acyclic pain in the pelvic region continuing for a long period of time. It has multifactorial etiology which may encompass gynecological, urological, gastrointestinal, musculoskeletal, and neurological components. This comprehensive review highlights the physical and psychological effects of CPP and briefly summarizes the various treatment modalities for CPP.
Domain-Driven Design in Cloud Computing: .NET and Azure Case Analysis
Authors: Jordanov Jordan , Petrov Pavel , Kuyumdzhiev Ivan , Vasilev Julian , Petrova Stefka
Published: February 2025

The study explores the integration of domain-driven design (DDD) with the cloud computing framework provided by the Microsoft Azure platform. Limited research exists that connects theoretical DDD principles with practical applications in cloud environments, and this research tries to focus on how DDD concepts could be effectively implemented in PaaS and IaaS cloud models. In this regard, the main research question is: How could DDD concepts be effectively applied on the Microsoft Azure platform using .NET services? The study hypothesizes that by applying the main components of the DDD, such as event-driven patterns, aggregates, and bounded contexts, one could significantly enhance the scalability, maintainability, and efficiency of the cloud applications. The research uses a case study approach as a main research method and evaluates the practical application of DDD within the context of Microsoft Azure’s cloud models. The study finds that DDD offers significant advantages in structuring cloud-native applications, especially in the design of application and data layers. Key findings of the study suggest that DDD, when combined with Azure's cloud capabilities, can provide a robust framework for building scalable, resilient software systems, although some problems remain in aligning theoretical DDD with practical cloud development frameworks.
Cognitive dysfunction after ischemic stroke
Authors: Ozdogru Derya , Erdem Miray
Published: February 2025

Objectives: One of the most important and common consequences of ischemic stroke is the cognitive impairment observed after stroke. This study aimed to investigate the role of strategic stroke among post-stroke cognitive impairment using the Montreal Cognitive Assessment Scale (MOCA).
Methods: This study was planned as a prospective cross-sectional study. Patients admitted between 3 and 12 months after stroke were included in the study. Patients who had a stroke at least 3 months ago, who had not been admitted for a year after the stroke, and who gave consent to participate in the study were considered as inclusion criteria.
Results: This study included 45 (44.1%) females and 57 (55.9%) males. When evaluated in terms of comorbidity, the frequency of hyperlipidemia was found to be significantly higher in the cognitively impaired group (46.5% vs. 25.4%, P=0.027). Thyroid stimulating hormone (TSH) levels were found to be lower in the Cognitive Impairment Group (0.93 μIU/mL vs. 1.03 μIU/mL, P=0.021). Considering the finding rates and significance level of lesion sites between the groups, the strategic infarction rate was found to be significantly higher in the cognitively impaired group (62.8% vs. 33.9%, P=0.004). In cognitive tests, the cognitive impairment group showed significantly lower performance in all areas (P<0.05).
Conclusions: It should be kept in mind that the MOCA scale can be a good evaluation scale in detecting patients with cognitive impairment after ischemic stroke.
Śluby
Authors: Przybyszewski Stanisław , Goławska-Stachowiak Karolina
Published: February 2025

PRZED LEKTURĄ
W przywołanej wcześniej recenzji Kornel Makuszyński, miarkując dyskretnie krytyczny sąd nad dramatem Śluby, sugeruje uwarunkować ocenę „oddaleniem”. Dziś, po ponad stu latach od pojawienia się dzieła, możliwe jest nie tylko oddalenie czasowe, ale i dystans poznawczy. Ponowne wydanie dramatu daje szansę na nowe jego odczytanie. To ważne — odczytanie właśnie, bo dramat Śluby jest ze wszech miar tekstem literackim.
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Karolina Goławska-Stachowiak
Implementation Of Quality Early Childhood Education: A Descriptive Study Of Inclusive Kindergartens In The Yogyakarta Region
Authors: Sari Rahma , Hibana
Published: February 2025

Parents and adults around children are obliged to guide, protect and provide education to children. Parents and adults around children should be able to create a safe and friendly environment for children. This environment is able to accept the exsistence of children, the characteristics of children, the differences of children regardless of background, religion, culture, language, social class, economy, gender, race, ethnicity, including children with special needs who are also given the same opportunity to receive guidance protection, and education. The presence of this environment is a solution to the many acts of discrimination and harassment against children, especially children with special needs (ABK). This environment is called and inclusive environment as an embodiment of quality early childhood education.
Management of the Indoor Learning Environment at Makarima Islamic Kindergarten in Sukoharjo
Authors: Noor Septiannisa Kartika , Riris Ananta  , Ditasya Sabrina Aisywara  , Ahmadi
Published: February 2025

This research discusses the management of the indoor learning environment at Makarima Islamic Kindergarten in Sukoharjo, focusing on effective learning management applied to create an environment that supports early childhood development. A descriptive qualitative approach with an ethnographic approach. The subjects of this study consisted of principals, teachers, and the environment. Researchers applied data collection techniques in the form of observation and documentation. The main findings show that the management of the indoor learning environment at Makarima Sukoharjo Islamic Kindergarten involves the selection of safe teaching materials, flexible and stimulative space arrangement, and learning equipment The use of colour, good lighting, and proper space layout is proven to affect children's attention and motivation in the learning process Makarima Sukoharjo Islamic Kindergarten has five types of rooms, namely the preparation centre, the design centre, the natural materials centre, the siroh role centre, and the life skills centre. This study concludes that controlling the learning environment is important to achieve effective learning goals in children.
Navigating Digital Frontiers: Estonia’s e-Residency through the Lens of the Eclectic Paradigm
Authors: Luhur Ken Budi , Trihartono Agus , Hara Abubakar Eby
Published: February 2025

The Estonian e-Residency program, launched in 2014, allows non-residents to access Estonia’s advanced digital infrastructure and services. It provides a secure digital identity to individuals worldwide, enabling them to start and manage a location-independent business online within the European Union without needing to physically reside in Estonia. This study explores the opportunities and challenges of e-Residency through qualitative methods and the Eclectic Paradigm model by John Dunning. While e-Residency does not grant physical residency, citizenship, or tax residency, is especially attractive to individuals seeking to leverage Estonia’s advanced digital infrastructure and favorable business environment. Key opportunities include leveraging Estonia’s advanced digital infrastructure and accessing the European Union market, significantly enhancing business efficiency and economic participation. However, the novelty of the e-Residency concept still faces challenges from the challenge of low global adoption, which requires optimization for broader relevance and impact. Lastly, this research underscores the need for strategic improvements to maximize the program’s potential and suggests further development to achieve its global aspirations.
Keywords: e-Residency, Digital Identity, Estonia, Eclectic Paradigm
Program e-Residency Estonia, yang diluncurkan pada tahun 2014, memungkinkan non-residen untuk mengakses infrastruktur dan layanan digital canggih Estonia. Program ini menyediakan identitas digital yang aman bagi individu di seluruh dunia, yang memungkinkan mereka untuk memulai dan mengelola bisnis daring yang tidak bergantung pada lokasi di Uni Eropa tanpa perlu bertempat tinggal secara fisik di Estonia. Studi ini mengeksplorasi peluang dan tantangan e-Residency melalui metode kualitatif dan model Paradigma Eklektik oleh John Dunning. Penelitian ini menemukan bahwa meskipun e-Residency tidak memberikan tempat tinggal fisik, kewarganegaraan, atau pajak tempat tinggal, tetapi sangat menarik bagi individu yang ingin memanfaatkan infrastruktur digital canggih Estonia dan lingkungan bisnis yang menguntungkan. Peluang utama termasuk memanfaatkan infrastruktur digital canggih Estonia dan mengakses pasar Uni Eropa, yang secara signifikan meningkatkan efisiensi bisnis dan partisipasi ekonomi. Namun, di sisi lain, kebaruan konsep e-Residency masih mengalami tantangan berupa adopsi global yang masih rendah sehingga memerlukan pengoptimalan untuk relevansi dan dampak yang lebih luas. Terakhir, penelitian ini menggarisbawahi perlunya peningkatan strategis untuk memaksimalkan potensi program dan menyarankan pengembangan lebih lanjut untuk mencapai aspirasi globalnya.
Kata-kata Kunci: e-Residency, Identitas Digital, Estonia, Paradigma Eklektik
DAMPAK SOSIAL EKONOMI PENATAAN DAN PEMBERDAYAAN PEDAGANG KAKI LIMA DI PANTAI PADANG
Authors:   Program Studi Magister Pengembangan Masyarakat Islam, Pascasarjana Universitas Islam Negeri Imam Bonjol, Putri Risya Nurya Ayyu , Azwar Welhendri ,   Program Studi Magister Pengembangan Masyarakat Islam, Pascasarjana Universitas Islam Negeri Imam Bonjol, Jamil Muhamad ,   Sekolah Tinggi Agama Islam Yastis
Published: February 2025

Penelitian ini mengkaji dampak sosial dan ekonomi dari penataan Pedagang Kaki Lima (PKL) di Pantai Padang, terutama terkait relokasi dan pembatasan waktu berjualan. Penelitian ini menggunakan metode kualitatif deskriptif dengan observasi dan wawancara mendalam. Hasilnya menunjukkan bahwa penataan sering merugikan PKL, mengakibatkan penurunan pendapatan dan ketidakpuasan karena lokasi baru yang kurang strategis. Meskipun ada janji pemerintah untuk menyediakan fasilitas memadai, banyak PKL merasa janji tersebut tidak terealisasi, yang menambah keresahan sosial dan ketidakpercayaan terhadap pemerintah. Konflik antara PKL dan pemerintah muncul di aspek sosial, sementara ekonomi PKL mengalami penurunan pendapatan yang signifikan, terutama bagi mereka yang bergantung pada lokasi ramai. Secara keseluruhan, penataan PKL di Pantai Padang belum berhasil, sehingga evaluasi lebih lanjut diperlukan untuk meningkatkan kesejahteraan pedagang dan memberikan panduan bagi pembuat kebijakan dalam merancang strategi pemberdayaan PKL yang lebih inklusif.
Kata kunci: Dampak, Penataan, Pedagang Kaki Lima
HUBUNGAN RELIGIUSITAS ISLAM DAN REGULASI EMOSI MAHASISWA UNTUK TERCAPAINYA SDGS KE-3
Authors:   Program Studi Psikologi, Fakultas Psikologi dan Ilmu Sosial Budaya, Universitas Islam Indonesia, Reskido Aleea Dian Putri , Sutra Shafira Dhaisani ,   Program Studi Psikologi, Fakultas Psikologi dan Ilmu Sosial Budaya, Universitas Islam Indonesia, Kurniawan Irwan Nuryana ,   Program Studi Psikologi, Fakultas Psikologi dan Ilmu Sosial Budaya, Universitas Islam Indonesia
Published: February 2025

Religiusitas Islam merupakan hal penting untuk diperhatikan, khususnya pada seorang muslim. Hal ini karena religiusitas Islam berperan terhadap seluruh aspek kehidupan manusia, tidak terkecuali pada mahasiswa Muslim yang memiliki banyak peran dan dituntut untuk produktif. Tujuan dari penelitian ini adalah untuk menjelaskan hubungan religiusitas Islam dan regulasi emosi pada mahasiswa muslim di Yogyakarta. Penelitian ini menggunakan pendekatan kuantitatif dengan metode studi korelasional. Teknik pengumpulan data menggunakan teknik purposive sampling dengan partisipan 154 mahasiswa muslim di Yogyakarta. Hipotesis penelitian ini adalah terdapat hubungan positif antara religiusitas Islam dan regulasi emosi pada mahasiswa muslim di Yogyakarta. Religiusitas Islam diukur dengan menggunakan A Psychological Measure of Islamic Religiousness oleh Abu Raiya et al. dan regulasi emosi diukur dengan Emotion Regulation Questionnaire (ERQ) oleh Gross & John. Hasil penelitian menunjukkan bahwa religiusitas Islam berkorelasi positif terhadap regulasi emosi. Kesimpulannya, semakin tinggi religiusitas Islam pada seseorang, maka semakin tinggi pula kemampuan regulasi emosinya.
Kata kunci: Religiusitas Islam, regulasi emosi, mahasiswa
JUSTIFICATION OF THE STRUCTURE OF THE MONITORING AND CONTROLLING SYSTEM AT AN AGRICULTURAL ENTERPRISE
Authors: Nosach N. , Yehiozarian A.
Published: February 2025

Abstract. The article is devoted to justifying the structure of the monitoring and controlling system at an agricultural enterprise. The study aims to develop theoretical and methodological foundations and practical recommendations for creating and implementing an effective monitoring and controlling system at enterprises, particularly in the agro-industrial sector, considering the specifics of their activities, modern market environment conditions, and sustainable development requirements.
The study presents the principles of integrating monitoring and controlling into the overall enterprise management system. Special attention is paid to using modern digital technologies, such as automated data collection and processing systems, business analytics, big data, and artificial intelligence. The study substantiates the feasibility of introducing monitoring as a process of continuous observation of the enterprise's key performance indicators. It was found that the central monitoring tasks include controlling the implementation of strategic and tactical plans, analyzing resource utilization efficiency, assessing market risks, and identifying deviations from planned indicators. Controlling is characterized as a system that includes planning, analysis, and decision-making, considering the enterprise's long-term goals.
The research revealed the critical role of controlling in ensuring sustainable enterprise development, cost optimization, and improving competitiveness. The article outlines the main elements of a comprehensive monitoring and controlling system: the information base, methodological support, operational and strategic control, and adjustment mechanisms. The importance of their interaction in creating an integrated system capable of functioning effectively in a volatile market environment is emphasized. Particular attention is paid to implementing such systems in agro-industrial enterprises. It is noted that applying an integrated approach to monitoring and controlling ensures adaptability to external challenges, risk reduction, and rational resource utilization, which is critically important for the industry. The study confirmed the effectiveness of monitoring and controlling as tools for improving enterprises' productivity, stability, and investment attractiveness. The conclusion is drawn on the necessity of implementing such systems to achieve strategic goals and ensure long-term development.
On the need to develop “formal education” as the main direction of continuous medical education: improving professional standards and advanced training programs.
Authors:   Expert on the issues of regulatory and legal regulation of health care activities, Piven D. V. , Kitsul I. S. ,   Irkutsk State Medical Academy of Postgraduate Education – the branch of the Russian Medical Academy of Continuing Professional Education of the Ministry of Health of the Russian Federation
Published: February 2025

In the article, the authors substantiate that the most promising and at the same time extremely necessary direction of development of continuous medical education today is the improvement of educational programs, namely advanced training programs, in organizations implementing educational activities, i. e. the development of «formal education». The material emphasizes that the legislation of Russia enshrines close continuity between professional standards and advanced training programs for medical workers, while the latter must take professional standards into account in full. At the same time, the article demonstrates that the current professional standards do not contain numerous characteristics of the qualifications that a medical worker must have in accordance with the mandatory requirements imposed today within the framework of state control (supervision) in the field of healthcare for the quality and safety of medical activities.
This problem, in turn, is mirrored on advanced training programs for medical workers. It is proposed to review and update all current professional standards for medical workers. In addition, in accordance with Part 3 of Article 82 of the Law on Education, it is necessary to develop sample additional professional programs for medical workers that fully disclose the mandatory requirements imposed by law on medical workers in terms of ensuring the quality and safety of medical activities.
Hubristik Liderlik Ölçeği: Bir Ölçek Geliştirme Çalışması
Authors: Uysal Şerife , Çelik Rukiye , Üngüren Engin
Published: February 2025

Liderlik konusu her zaman merak edilen, araştıran ve araştırmaya devam edilen bir konudur. Çünkü liderlerin davranışları ve kararları toplum ve işletmeleri derinden etkilemektedir. Haliyle liderlik çalışmaları liderlik özelliklerinin örgütleri nasıl başarıya ulaşabileceğinin yanı sıra nasıl başarısızlığa götürebileceğine dair kanıtlar sunmaktadır. Hubris sendromu ve hubristik davranışlara ilişkin kapsamlı bir akademik yazın olmasına rağmen Hubristik Liderliği değerlendirecek nitelikte elverişli bir ölçme aracı bulunmamaktadır. Bu problemden hareketle çalışmanın amacı çok boyutlu Hubristik Liderlik Ölçeği geliştirmek ve test etmektir. Sağlık çalışanları ve akademisyenler ile gerçekleştirilen yarı yapılandırılmış görüşmelerin analizinden elde edilen ve uzman görüşü ile son hali verilen 35 maddelik Hubristik Liderlik Ölçeği 491 öğretim elemanı ve öğretim üyesine uygulanmıştır. Keşfedici ve doğrulayıcı faktör analizi sonucunda, güvenilir, yakınsak ve ayırt edici geçerliliğe sahip, 35 madde ve altı boyuttan oluşan Hubristik Liderlik ölçeği elde edilmiştir. Elde edilen boyutlar büyüklük sanrısı, istismar etme, küçümseme ve aşağılama, güç baskısı, sosyal beğenirlik ve imaj olarak isimlendirilmiştir. Elde edilen bulgular ışığında Hubristik Liderlik Ölçeğinin geçerli ve güvenilir bir ölçüm aracı olduğu sonucuna ulaşılmıştır.
Dijital Pazarlama ve Müşteri İlişkileri Yönetiminin Tekrar Satın Alma Niyeti Üzerine Etkisi ve Marka Farkındalığının Aracılık Rolü
Authors: Köroğlu Ali , Avcı İbrahim
Published: February 2025

Son dönemlerde birçok sektörde hem ulusal hem de uluslararası markaların faaliyet göstermesi müşterinin önemini daha da arttırmış, markalar günümüz rekabet şartlarında yeni müşteri kazanmak ve mevcut müşterileri elde tutmak için müşteri ilişkileri yönetimi ve dijital pazarlama faaliyetlerine önem vermeye başlamışlardır. Araştırmanın amacı markaların dijital pazarlama ve müşteri ilişkileri yönetimi faaliyetlerinin tüketicilerin tekrar satın alma niyeti üzerindeki etkilerini ve bu etkilerde marka farkındalığının aracılık rolünü ortaya koymaktır. Bu amaçla veriler 15 Eylül-15 Ekim 2023 tarih aralığında Tokat ilinde yaşayan 18 yaş üstü tüketicilerden yüz yüze anket tekniği ile toplanmıştır. Veri toplama süreci sonunda 419 tüketici ankete katılmış ve bu katılımcılardan elde edilen veriler istatistik paket programları aracılığıyla analiz edilmiştir. Yapılan analizler sonucunda dijital pazarlama ve müşteri ilişkileri yönetiminin tekrar satın alma niyeti üzerinde pozitif yönde anlamlı etkilerinin olduğu, bu etkilerde ise marka farkındalığının aracılık rolüne sahip olduğu belirlenmiştir. Elde edilen bu sonuçlar teorik ve uygulama açısından alana önemli katkılar sağlamaktadır.
Yeşil Müşteri Tatmininin Yeşil Güven Üzerindeki Etkisinde Yeşil Marka Farkındalığının Düzenleyici Rolü
Authors: Topaloğlu Gökhan
Published: February 2025

Bu araştırma yeşil müşteri tatmini, yeşil güven ve yeşil marka farkındalığı arasındaki ilişkinin yanı sıra yeşil müşteri tatmininin yeşil güven üzerindeki etkisinde yeşil marka farkındalığının düzenleyici etkisinin tespit edilmesi amacıyla gerçekleştirilmiştir. Veriler anket tekniği kullanılarak elde edilmiştir. Bu amaçla İzmir’de bulunan 287 tüketicinin katılımı ile anket çalışması gerçekleştirilmiştir. Veri analizinde SPSS 22 ve AMOS programları kullanılmıştır. Araştırmada faktör analizi, korelasyon analizi ve düzenleyicilik analizleri kullanılmıştır. Doğrulayıcı faktör analizinde x2/sd, CFI, RMSEA, GFI ve TLI uyum indeks değerlerinin uygun olup olmadığı değerlendirilmiştir. Yapılan analiz sonucunda uyum indeks değerlerinin kabul edilebilir sınır aralığında olduğu tespit edilmiştir. Düzenleyici etki analizi için AMOS programında uygun istatiksel model kurularak analiz yapılmıştır. Düzenleyici etkinin yorumlanabilmesi için literatürde sıklıkla kullanılan etkileşim etki grafiğinden yararlanılmıştır. Bulgulara bakıldığında yeşil müşteri tatmini, yeşil güven ve yeşil marka farkındalığı arasında anlamlı ilişki olduğu görülmektedir. Ayrıca yeşil müşteri tatmininin yeşil güven üzerindeki etkisinde yeşil marka farkındalığının düzenleyici etkisinin olduğu tespit edilmiştir.
Demografik Değişkenler Işığında Muhasebe Hata ve Hilelerine Yönelik Bir Saha Araştırması: Van İli Örneği
Authors: Seyitoğulları Osman
Published: February 2025

Bu araştırmanın amacı, demografik değişkenler ekseninde muhasebe meslek mensuplarının hata ve hilelere yönelik yaklaşımlarının tespit edilmesidir. Bu doğrultuda, Van Serbest Muhasebeci Mali Müşavirler Odası’na kayıtlı 245 meslek mensubundan yüz yüze anket aracılığıyla veriler toplanmıştır. Verilerin analizi aşamasında t testi, one way anova analizi ve post hoc testinden yararlanılmıştır. Yapılan analizler sonucunda katılımcı meslek mensuplarının hata ve hilelere yönelik yaklaşımlarında cinsiyet faktörünün belirleyici bir rol üstlenmediği görülmüştür. Araştırmaya katkı sunan muhasebe meslek mensuplarının yaş açısından hata ve hilelere yönelik yaklaşımlarının farklılık sergilediği belirlenmiştir. Katılımcıların yaşları ilerledikçe hata ve hilelere yönelik duyarlılıklarının düştüğü gözlenmiştir. Çalışma süresinin katılımcı muhasebe meslek mensuplarının hatalara yönelik yaklaşımlarında belirleyici bir işlev gösterdiği keşfedilmiştir. Tecrübe açısından meslekte yeni olan meslek mensuplarının muhasebe hatalarına karşı daha hassas bir tutum sergiledikleri çalışma kapsamında tespit edilmiştir.
Şartlı Mültecilerin Barınma Deneyimleri: “Yıkık ve Kötü Olmasına Rağmen Bu Evi Tuttuk Çünkü Mecburduk”
Authors: Aygüler Edip , Ayalp Mustafa Çağrı , Buz Sema
Published: February 2025

Bu araştırmanın amacı Ankara’daki şartlı mültecilerin, nerede ve hangi şartlar altında barındıklarının anlaşılması ve ev bulma süreçleri ile komşularla kurdukları ilişkilerin kendilerinin gözünden değerlendirilmesidir. Bunun için 15 şartlı mülteci ve onlara hizmet sunan sivil toplum kuruluşlarında görev yapan 17 profesyonel olmak üzere toplam 32 kişi ile derinlemesine görüşmeler gerçekleştirilmiş ve elde edilen veriler tümevarımsal tematik analize tabi tutulmuştur. Analiz sonucunda “Şartlı mültecilerin mevcut politika ve hizmetlerin yetersizliğinden ötürü karşılaştıkları sorunlar", "Ev bulma ve komşularla ilişki kurma süreci" ve "Şartlı mültecilerin yaşadıkları konutların özellikleri” olmak üzere üç temaya ulaşılmıştır. Araştırma sonucunda şartlı mültecilerin genellikle ciddi barınma sorunlarıyla karşılaştıkları ve bunun da yaşam kalitelerini önemli ölçüde etkilediği anlaşılmıştır. Şartlı mültecilere barınma konusunda yeterli desteğin sunulmayışı koşullarının kötüleşmesine yol açmaktadır. Bundan ötürü bu alandaki çabaların artırılmasına ihtiyaç vardır ve politika yapıcılar bir konut politikası geliştirmek ve barınma hakkına erişimi iyileştirmek için harekete geçmelidir.
Orientation and motivational determinants of social consciousness
Authors: Momdzhyan Karen
Published: February 2025

В статье рассматриваются знания и ценности как инварианты родового человече­ского сознания, связанные с его ориентационной и мотивационной ролью в дея­тельности людей. Задачей ориентационного сознания является познание окружаю­щего и охватывающего нас мира (существование которого постулируется как аксио­ма, сомнение в которой делает существование людей де-факто невозможным). Познание ищет собственную логику бытия воспринимаемого мира, дает нам вери­фицируемые знания о нем, отличные от незнаний и заблуждений. Мотивационная функция сознания предполагает экспертизу возможных реакций на безальтернатив­ные влечения человека для выбора оптимального из вариантов поведения. Автор рассматривает три уровня мотивационной экспертизы – эмоциональный, рассудоч­ный и облигаторный – которыми руководствуются люди, вынужденные выбирать между императивами приятного, полезного и должного. Мотивы долженствования образуют ценностное сознание людей – системную совокупность стратегических предпочтений, связанных с выбором приоритетных конечных целей жизни и, далее, фундированных ими потребностей. Конечные цели жизни автор связывает с генети­чески заданными экзистенциальными влечениями к сохранению факта и приемле­мого качества жизни. Потребность рассматривается как объективно-реальное свой­ство социального субъекта испытывать надобность в том, что необходимо для дости­жения конечных целей жизни. Экзистенциальные влечения и потребности не могут быть “отменены” человеческой волей, что не мешает ей вмешиваться в процесс их реализации, делая возможным экзистенциальный выбор между бытием и небыти­ем, а также ценностное ранжирование потребностей. В статье рассматривается де­терминационная связь между исторически неизменными, видоспецифическими по­требностями людей и их базовыми ценностями, имеющими универсальный харак­тер. Различия в ценностном сознании людей, принадлежащих разным обществам и культурам, автор связывает не с набором базовых ценностей, а с субординацион­ными связями между ними, которые формируют разные ценностные приоритеты. Автор настаивает на фундаментальном различии между знаниями и ценностями, которое связано с разным отношением к институту истины, неверифицируемостью ценностных предпочтений человека, ориентированных на мир должного, а не сущего.
Explainable AI-driven heterogeneity using coagulation–inflammatory markers improves prognosis prediction, risk stratification, and anticoagulant treatment effects for sepsis
Authors: Niu Bailin , Zhu Li , Chen Zengtian , Zhang Hong , Chen Hongjun , Liu Lanqi , Yu Wei , Wu Kai , Chen Yijin , Tao Xingyu , Yu Zefeng , Shi Linhui , Wang Jialian , Zhang Fan , Shen Jiaying , Liu Fen , Hu Chongke , Ren Yangguang , Liu Tzu-Ming , Luo Yang , Guo Fei
Published: February 2025

Sepsis, a leading cause of hospital mortality, is characterized by substantial heterogeneity, hindering the development of effective and interpretable prognostic and stratification methods. To address this challenge, we developed an explainable prognostic model (SepsisFormer, a transformer-based deep neural network with an enhanced domain-adaptive generator) and an automated risk stratification tool (SMART, a scorecard consistent with medical knowledge). In a multicenter retrospective study of 12,408 sepsis patients, SepsisFormer achieved high predictive accuracy (AUC: 0.9301, sensitivity: 0.9346, and specificity: 0.8312). SMART (AUC: 0.7360) surpassed most established scoring systems. Seven coagulation-inflammatory routine laboratory measurements and patient age were identified to classify patients' four risk levels (mild, moderate, severe, dangerous) and two subphenotypes (CIS1 and CIS2), each with distinct clinical characteristics and mortality rates. Notably, patients with moderate or severe levels or CIS2 derive more significant benefits from anticoagulant treatment. In conclusion, explainable artificial intelligence can potentially improve sepsis outcomes by uncovering patient heterogeneity.
Seasonal Variations in Otorhinolaryngology Case Presentations: Findings from a Pilot Study in a Tertiary Care Teaching Hospital in Mardan
Authors: imad Imad , Ahmad Miraj , Shah Syed Muddasir , Said Muhammad , Khattak Naeem , Rehman Ishtiaq Ur Rehman Ur , Uddin Iftikhar
Published: February 2025

Background:
This retrospective study aimed to examine the seasonal variations in the prevalence of otorhinolaryngological (ORL) disorders at a prominent teaching hospital in Mardan, spanning from October 2023 to September 2024. By analyzing patient data from the Otolaryngology, Head and Neck Department, this study explored the seasonal trends in ORL conditions, considering the type of disorder, time of presentation, and demographic characteristics.
Results:
The study revealed significant seasonal variations in the prevalence of ORL conditions. Otitis media showed a marked increase during the spring and summer months, while upper respiratory tract infections, such as acute sinusitis and rhinitis, were more frequent in colder months. Notably, there was a rise in cases of epistaxis and tonsillitis during transitional seasons, which could be influenced by fluctuating environmental conditions and immune responses. The study also identified the 16–30 years age group as the most affected, indicating that young adults are particularly vulnerable to seasonal ORL conditions. Surgical case volumes exhibited seasonal fluctuations, with peak months observed in spring and autumn. Tonsillectomy and septoplasty were more common in winter, while functional endoscopic sinus surgeries (FESS) peaked in spring.
Conclusions:
This study highlights the seasonal patterns in otorhinolaryngological disorders, emphasizing the importance of incorporating these variations into clinical practice. Understanding these patterns can aid in optimizing healthcare resource allocation, improving patient care, and developing targeted prevention and management strategies. This approach is essential for better addressing the seasonal impact on ORL disorders.
The Effect of Physical Activity Intensity On All-cause and Cardiovascular Mortality in Diabetic Patients
Authors: Wang Yali , Sun Lingling , Zhang Zhi , Jin Hongfeng , Tang Lijiang , Du Changqing , Liu Xiaowei
Published: February 2025

Background To assess the association between physical activity (PA) and mortality risk, few data are available to guide clinical recommendations for individuals with high levels of PA in the presence of clinically diagnosed diabetes.Methods Data on diabetic patients (aged 18 to 85 years) were acquired from the United States (US) National Health and Nutrition Examination Survey (NHANES) 1999–2018. The patients were divided into three groups based on the level and frequency of PA: a) sedentary (n = 2,152), b) moderate PA (n = 504), and c) vigorous PA (n = 1,708). Logistic regression analysis was used to determine the relationship between PA and all-cause mortality (ACM) or cardiovascular mortality (CVM) in diabetic patients.Results Among 4,364 adult respondents (54% men, 46% women, mean age 60.44 ± 15.4 years), 50.69% reported adequate PA. During the study, there were 283 (6.48%) deaths from cardiovascular disease (CVD) and 937 (21.47%) deaths from all causes. The incidence of all-cause or CVM was highest in the sedentary group. Patients who undertook sedentary PA had the highest risk of ACM (odds ratio [OR] 2.18; 95% confidence interval [CI] 1.69–2.82; P < 0.01) or CVM (OR 1.69; 95% CI 1.07–2.66; P < 0.01) compared to those in the moderate PA group. Vigorous PA did not further improve efficacy.Conclusions There is evidence that moderate PA is associated with reduced all-cause or CVM in diabetes after a decade of follow-up, but vigorous PA is not associated with further reductions in all-cause or cardiovascular mortality.
Why are iron chelators not as effective as artemisinin in killing malaria parasites?
Authors: Sun Jun , Fang Chuantao , Si Wenwen , Qin Xixi , Wang Fei , Li Yanna , Yan Xiaoli
Published: February 2025

Background
It is currently established that artemisinin kills malaria parasites by disrupting iron or haem utilization. Similarly, iron chelators also eliminate these parasites by interfering with iron utilization. However, the antimalarial effect of artemisinin is significantly greater than that of iron chelators. Understanding the differences between these two mechanisms is beneficial for elucidating the antimalarial action of artemisinin and for developing strategies to enhance artemisinin-based combination therapies.
Methods
We employed single-cell RNA sequencing analysis to assess the sensitivity of different stages of P. falciparum 3D7 to dihydroartemisinin (DHA) and desferrioxamine (DFO) at 3, 9, and 24 hours post-treatment. Additionally, we compared the distinct antimalarial effects of artemether, DHA, and DFO on malaria parasites in vitro and in vivo. Transmission electron microscopy (TEM) was utilized to observe the effects of artemisinin on the parasites.
Results
Our findings indicate that P. falciparum 3D7 is more sensitive to DFO than DHA at 12, 18, 24, and 30 hours post-infection; however, 24 hours post-treatment, all stages exhibit greater sensitivity to DHA than DFO. Notably, at 3 hours post-treatment with DFO and DHA, the number of various stages changed minimally, yet iron utilization-related genes were significantly upregulated only in the DHA treatment group. Gene expression analysis revealed that the actions of DFO and DHA result in the expression of different genes, particularly those involved in ribosome synthesis and protein translation in the DHA treatment group. Although both DHA and DFO can reduce the infection rate of P. falciparum 3D7 in vitro, DFO fails to inhibit the growth of Plasmodium yoelii 17XNL in vivo. Furthermore, the combined effect of DHA and DFO is weaker than that of DHA alone. TEM analysis demonstrates that artemether disrupts haem aggregation within the digestive vacuole of malaria parasites.
Conclusions
While both artemisinin and iron chelators can disturb or prevent iron utilization, they kill malaria parasites through distinct mechanisms and yield different effects. Notably, the accumulation of artemisinin and its unique interaction with haem in the digestive vacuole facilitate a more efficient and specific antimalarial effect of artemisinin.
Real-space imaging of ultrafast electron dynamics and subsequent crystallographic dynamics via photo-induced phase transition
Authors: Fukumoto Keiki , Onda Ken , Tanaka Takanori , Kusakabe Koichi , Yamochi Hideki , Adachi Shin-ichi , Koshihara Shin-ya
Published: February 2025

Photo-induced phase transition (PIPT) involves substantial changes in both electronic and crystallographic structures caused by electron excitations. Because PIPT is ultrafast and exhibits inhomogeneous behaviour, its fundamental processes, in particular how the ultrafast dynamics of photoexcited electrons trigger lattice deformation and the time scales involved, remain poorly understood. In this study, the dynamics of the photoexcited electrons and the subsequent volume change of organic charge transfer complexes are directly visualised simultaneously in the time and energy domains using photoemission electron microscopy with a femtosecond pulsed laser as the excitation source. The results show that an anisotropic volume change of a few percent is initiated following the accumulation of electrons in unoccupied states over approximately a picosecond.
The mechanism of charge transfer between quantum dots and redox molecules
Authors: Vogel Yan , Boeije Willemijn , Steekelenburg Lotte van , Vollebregt Demi , Ubbink Reinout , Chen Hua , Younesi Ali , Ulbricht Ronald , Jager Wolter , Grozema Ferdinand , Houtepen Arjan
Published: February 2025

Charge transfer between quantum dots (QDs) and redox molecules is not well described by the Marcus theory, the hall-mark theory for charge transfer in molecular systems. The Marcus inverted region, where the rate decreases with increasing the free energy difference, has never been observed in QDs. The previously reported hypothesis for the absence of the Marcus inverted region in QDs is an Auger-assisted charge transfer pathway. Here, we show that the Auger hypothesis does not hold to experimental tests. Instead, our experimental results suggest the presence of a distribution of molecular configurations on the QD surface that results in multiple energy surfaces. We measured the rate constants for two processes where Auger is either allowed or not: charge separation and charge recombination. We used ultrafast transient absorption spectroscopy to probe the rate of charge separation and recombination between PbS QDs and ferrocene derivatives ligands bound to their surface. We find that the rate constant for both charge separation and recombination increase by increasing the free energy difference, are temperature-independent, and increase with the number of molecular acceptors. All these results are against theoretical predictions for an Auger-assisted charge transfer and suggest the presence of multiple molecular configurations with charge transferring through the most favorable pathway.