bluuebunny/crossref_metadata_2025 huggingface dataset:
Going Next after “A Guide to Special Functions in Fractional Calculus”: A Discussion Survey
Authors: Kiryakova Virginia , Paneva-Konovska Jordanka
Published: January 2024

In the survey Kiryakova: “A Guide to Special Functions in Fractional Calculus” (published in this same journal in 2021) we proposed an overview of this huge class of special functions, including the Fox H-functions, the Fox–Wright generalized hypergeometric functions pΨq and a large number of their representatives. Among these, the Mittag-Leffler-type functions are the most popular and frequently used in fractional calculus. Naturally, these also include all “Classical Special Functions” of the class of the Meijer’s G- and pFq-functions, orthogonal polynomials and many elementary functions. However, it so happened that almost simultaneously with the appearance of the Mittag-Leffler function, another “fractionalized” variant of the exponential function was introduced by Le Roy, and in recent years, several authors have extended this special function and mentioned its applications. Then, we introduced a general class of so-called (multi-index) Le Roy-type functions, and observed that they fall in an “Extended Class of SF of FC”. This includes the I-functions of Rathie and, in particular, the H¯-functions of Inayat-Hussain, studied also by Buschman and Srivastava and by other authors. These functions initially arose in the theory of the Feynman integrals in statistical physics, but also include some important special functions that are well known in math, like the polylogarithms, Riemann Zeta functions, some famous polynomials and number sequences, etc. The I- and H¯-functions are introduced by Mellin–Barnes-type integral representations involving multi-valued fractional order powers of Γ-functions with a lot of singularities that are branch points. Here, we present briefly some preliminaries on the theory of these functions, and then our ideas and results as to how the considered Le Roy-type functions can be presented in their terms. Next, we also introduce Gelfond–Leontiev generalized operators of differentiation and integration for which the Le Roy-type functions are eigenfunctions. As shown, these “generalized integrations” can be extended as kinds of generalized operators of fractional integration, and are also compositions of “Le Roy type” Erdélyi–Kober integrals. A close analogy appears with the Generalized Fractional Calculus with H- and G-kernel functions, thus leading the way to its further development. Since the theory of the I- and H¯-functions still needs clarification of some details, we consider this work as a “Discussion Survey” and also provide a list of open problems.
(R, S)-(Skew) Symmetric Solutions to Matrix Equation AXB = C over Quaternions
Authors: Liao Ruopeng , Liu Xin , Long Sujuan , Zhang Yang
Published: January 2024

(R,S)-(skew) symmetric matrices have numerous applications in civil engineering, information theory, numerical analysis, etc. In this paper, we deal with the (R,S)-(skew) symmetric solutions to the quaternion matrix equation AXB=C. We use a real representation Aτ to obtain the necessary and sufficient conditions for AXB=C to have (R,S)-(skew) symmetric solutions and derive the solutions when it is consistent. We also derive the least-squares (R,S)-(skew) symmetric solution to the above matrix equation.
Cardiovascular Disease and Chronic Pulmonary Disease Increase the Risk of Short-Term Major Postoperative Complications after Robotic-Assisted Radical Prostatectomy
Authors: Siech Carolin , Gruber Antonia , Wenzel Mike , Humke Clara , Karakiewicz Pierre I. , Kluth Luis A. , Chun Felix K. H. , Hoeh Benedikt , Mandel Philipp
Published: January 2024

Background and objectives: Certain comorbidities may be associated with a higher risk of complications after robotic-assisted radical prostatectomy. Material and Methods: Relying on a tertiary care database, we identified robotic-assisted radical prostatectomy patients (January 2014–March 2023). Short-term major postoperative complications were defined according to Clavien Dindo as ≥IIIa within 30 days after robotic-assisted radical prostatectomy. Results: Of 1148 patients, the rates of postoperative Clavien Dindo IIIa, Clavien Dindo IIIb, Clavien Dindo IVa, and Clavien Dindo IVb complications were 3.3%, 1.4%, 0.3%, and 0.2%, respectively. Of those, 28 (47%) had lymphoceles, and 8 (13%) had bleeding-associated complications. Patients with cardiovascular disease (8 vs. 4%) or chronic pulmonary disease (13 vs. 5%) were more likely to have complications. In multivariable logistic regression models, cardiovascular disease (odds ratio: 1.78; p = 0.046) and chronic pulmonary disease (odds ratio: 3.29; p = 0.007) remained associated with an increased risk of postoperative complications. Conclusions: Complications after robotic-assisted radical prostatectomy are predominantly manageable without anesthesia. Concomitant cardiovascular disease and chronic pulmonary disease were both associated with a higher risk of postoperative complications.
Belgian Cross-Sectional Epidemiological Study on Zoonotic Avian Chlamydia spp. in Chickens
Authors: De Meyst Anne , De Clercq Pieter , Porrez Jelmer , Geens Tom , Braeckman Lutgart , Ouburg Sander , Morré Servaas A. , Vanrompay Daisy
Published: January 2024

Chlamydia psittaci, Chlamydia gallinacea, and Chlamydia abortus are the most common Chlamydia spp. in chickens and have a confirmed or suggested zoonotic potential. No recent data are available on their prevalence and impact in the Belgian chicken industry or in the recreational chicken branch. Therefore, a cross-sectional epidemiological study was executed where samples were collected from both factory-farmed and backyard chickens. More specifically, pharyngeal chicken swabs were obtained from 20 chicken farms, 5 chicken abattoirs, and 38 different backyard locations and were analyzed using species-specific Polymerase Chain Reactions (PCRs) for the presence of the three avian Chlamydia spp. To investigate their zoonotic potential, samples were simultaneously collected from 54 backyard chicken caretakes and 37 professional chicken caretakers or abattoir employees and analyzed using species-specific PCRs as well. This study confirmed the presence of DNA of all three Chlamydia species in both the chicken industry and backyard settings. Chlamydia psittaci was the most prevalent in the industry chickens (11.0%), whereas Chlamydia gallinacea was the dominant species in the backyard chickens (14.5%). Chlamydia abortus infections were more common in the commercial chickens (9.0%) compared to the backyard chickens (2.6%). The DNA of all three species was also detected in humans (3.9% Chlamydia psittaci, 2.9% Chlamydia gallinacea, and 1.0% Chlamydia abortus).
The Networked Interaction between Probiotics and Intestine in Health and Disease: A Promising Success Story
Authors: Skoufou Maria , Tsigalou Christina , Vradelis Stergios , Bezirtzoglou Eugenia
Published: January 2024

Probiotics are known to promote human health either precautionary in healthy individuals or therapeutically in patients suffering from certain ailments. Although this knowledge was empirical in past tomes, modern science has already verified it and expanded it to new limits. These microorganisms can be found in nature in various foods such as dairy products or in supplements formulated for clinical or preventive use. The current review examines the different mechanisms of action of the probiotic strains and how they interact with the organism of the host. Emphasis is put on the clinical therapeutic use of these beneficial microorganisms in various clinical conditions of the human gastrointestinal tract. Diseases of the gastrointestinal tract and particularly any malfunction and inflammation of the intestines seriously compromise the health of the whole organism. The interaction between the probiotic strains and the host’s microbiota can alleviate the clinical signs and symptoms while in some cases, in due course, it can intervene in the underlying pathology. Various safety issues of the use of probiotics are also discussed.
Diverse Small Circular DNA Viruses Identified in an American Wigeon Fecal Sample
Authors: Olivo Diego , Khalifeh Anthony , Custer Joy M. , Kraberger Simona , Varsani Arvind
Published: January 2024

American wigeons (Mareca americana) are waterfowls that are widely distributed throughout North America. Research of viruses associated with American wigeons has been limited to orthomyxoviruses, coronaviruses, and circoviruses. To address this poor knowledge of viruses associated with American wigeons, we undertook a pilot study to identify small circular DNA viruses in a fecal sample collected in January 2021 in the city of Tempe, Arizona (USA). We identified 64 diverse circular DNA viral genomes using a viral metagenomic workflow biased towards circular DNA viruses. Of these, 45 belong to the phylum Cressdnaviricota based on their replication-associated protein sequence, with 3 from the Genomoviridae family and the remaining 42 which currently cannot be assigned to any established virus group. It is most likely that these 45 viruses infect various organisms that are associated with their diet or environment. The remaining 19 virus genomes are part of the Microviridae family and likely associated with the gut enterobacteria of American wigeons.
Interaction of Aromatic Amino Acids with Metal Complexes of Tetrakis-(4-Sulfonatophenyl)Porphyrin
Authors: Zagami Roberto , Castriciano Maria Angela , Trapani Mariachiara , Romeo Andrea , Monsù Scolaro Luigi
Published: January 2024

The interaction of a series of metal derivatives of 5, 10, 15, 20-tetrakis(4-sulfonato-phenyl)porphyrin (MTPPS4, M = Cu(II), Pt(II), Ni(II), Zn(II) and Co(II)), including the metal free porphyrin (TPPS4), with the aromatic amino acids L-tryptophan (L-Trp), L-and D-phenylalanine (L-and D-Phe) and L-histidine (L-His) have been investigated through UV/Vis spectroscopy. The amino acid L-serine (L-Ser) has been included as reference compound. The spectroscopic changes induced by adding the amino acids have been exploited to evaluate the extent of interaction between the molecular components in the supramolecular adducts. The binding constants have been estimated for most of the investigated systems, assuming a simple 1:1 equilibrium. The bathochromic shifts of the B-bands, the extent of hypochromicity and the binding constants have been analyzed through two chemical descriptors. All the data point to the important role played by the steric hindrance introduced by axial ligands coordinated to the metal ions and to the degree of hydrophobicity and size of the aromatic moiety in the amino acids.
An Overview of Cannabidiol as a Multifunctional Drug: Pharmacokinetics and Cellular Effects
Authors: Martinez Naya Nadia , Kelly Jazmin , Corna Giuliana , Golino Michele , Polizio Ariel H. , Abbate Antonio , Toldo Stefano , Mezzaroma Eleonora
Published: January 2024

Cannabidiol (CBD), a non-psychoactive compound derived from Cannabis Sativa, has garnered increasing attention for its diverse therapeutic potential. This comprehensive review delves into the complex pharmacokinetics of CBD, including factors such as bioavailability, distribution, safety profile, and dosage recommendations, which contribute to the compound’s pharmacological profile. CBD’s role as a pharmacological inhibitor is explored, encompassing interactions with the endocannabinoid system and ion channels. The compound’s anti-inflammatory effects, influencing the Interferon-beta and NF-κB, position it as a versatile candidate for immune system regulation and interventions in inflammatory processes. The historical context of Cannabis Sativa’s use for recreational and medicinal purposes adds depth to the discussion, emphasizing CBD’s emergence as a pivotal phytocannabinoid. As research continues, CBD’s integration into clinical practice holds promise for revolutionizing treatment approaches and enhancing patient outcomes. The evolution in CBD research encourages ongoing exploration, offering the prospect of unlocking new therapeutic utility.
Design, Synthesis, and Biological Evaluation of 2-Substituted Aniline Pyrimidine Derivatives as Potent Dual Mer/c-Met Inhibitors
Authors: Huang Daowei , Chen Ying , Yang Jixia , Zhao Bingyang , Wang Shouying , Chai Tingting , Cui Jie , Zhou Xiaolei , Shang Zhenhua
Published: January 2024

Mer and c-Met kinases, which are commonly overexpressed in various tumors, are ideal targets for the development of antitumor drugs. This study focuses on the design, synthesis, and evaluation of several 2-substituted aniline pyrimidine derivatives as highly potent dual inhibitors of Mer and c-Met kinases for effective tumor treatment. Compound 18c emerged as a standout candidate, demonstrating robust inhibitory activity against Mer and c-Met kinases, with IC50 values of 18.5 ± 2.3 nM and 33.6 ± 4.3 nM, respectively. Additionally, compound 18c displayed good antiproliferative activities on HepG2, MDA-MB-231, and HCT116 cancer cells, along with favorable safety profiles in hERG testing. Notably, it exhibited exceptional liver microsomal stability in vitro, with a half-life of 53.1 min in human liver microsome. Compound 18c also exhibited dose-dependent cytotoxicity and hindered migration of HCT116 cancer cells, as demonstrated in apoptosis and migration assays. These findings collectively suggest that compound 18c holds promise as a dual Mer/c-Met agent for cancer treatment.
Phenolic Content Analysis of Two Species Belonging to the Lamiaceae Family: Antioxidant, Anticholinergic, and Antibacterial Activities
Authors: Ndhlala Ashwell R. , Işık Mesut , Kavaz Yüksel Arzu , Dikici Emrah
Published: January 2024

The Lamiaceae family are utilized as ornamental, medicinal, and food supplements throughout the world. The current study focuses on a comparative analysis of the phenolic compositions and bioactivities (including antioxidant, anticholinergic, and antibacterial activities) of ethanolic extracts derived from the aerial parts of the two species (Lavandula stoechas L. and Thymus sipyleus Boiss). The presence of phenolic compounds and phytochemicals in the plant extracts was identified using the LC-MS/MS technique. The LC-MS/MS analysis revealed that vanillic acid (125,596.66 µg/L) was the most abundant phytochemical in L. stoechas. Kaempferol (8550.52 µg/L) was the most abundant substance in Thymus sipyleus. The assessment of the antioxidant efficacy of the species extracts was conducted using the DPPH (2.2-diphenyl-1-picryl-hydrazyl-hydrate), ABTS (2.2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid)), Fe3+–Fe2+ reducing, and CUPRAC (Cu2+–Cu+ reducing) assays. The anticholinergic activity of the samples was determined using the acetylcholinesterase (AChE) inhibition assay. The results of antioxidant activity were higher in the T. sipyleus than in the L. stoechas ethanol extracts. The extracts of L. stoechas exhibited radical scavenging activity ranging from 15 to 18%, while T. sipyleus had activity effects ranging from 34% to 38%. The AChE inhibition potential for L. stoechas and T. sipyleus extracts as IC50 values were 0.221 ± 0.01 mg/mL and 0.067 ± 0.02 mg/mL, respectively. The antibacterial effects of the ethanolic extracts of these species against pathogenic bacteria isolates were determined using the MIC (minimal inhibitory concentration) method. These findings indicated that the extracts from L. stoechas and T. sipyleus possess the potential to be natural antioxidants in the realm of food preservation. Additionally, their antioxidant, anticholinergic, and antimicrobial properties suggest potential therapeutic utility in the management of certain diseases.
Structure-Antitumor Activity Relationships of Aza- and Diaza-Anthracene-2,9,10-Triones and Their Partially Saturated Derivatives
Authors: Avendaño Carmen , López-Alvarado Pilar , Pérez José María , Alonso Miguel Ángel , Pascual-Alfonso Eva , Ruiz-Serrano Miriam , Menéndez J. Carlos
Published: January 2024

The 1,8-Diazaanthracene-2,9,10-triones, their 5,8-dihydro derivatives, and 1,8-diazaanthracene-2,7,9,10-tetraones, structurally related to the diazaquinomycin family of natural products, were synthesized in a regioselective fashion employing Diels–Alder strategies. These libraries were studied for their cytotoxicity in a variety of human cancer cell lines in order to establish structure–activity relationships. From the results obtained, we conclude that some representatives of the 1,8-diazaanthracene-2,9,10-trione framework show potent and selective cytotoxicity against solid tumors. Similar findings were made for the related 1-azaanthracene-2,9,10-trione derivatives, structurally similar to the marcanine natural products, which showed improved activity over their natural counterparts. An enantioselective protocol based on the use of a SAMP-related chiral auxiliary derived was developed for the case of chiral 5-substituted 1,8-diazaanthracene-2,9,10-triones, and showed that their cytotoxicity was not enantiospecific.
A Sub-Picosecond Laser System Based on High-Energy Yb:YAG Chirped-Pulse Regenerative Amplification
Authors: Wu Minjian , Geng Yixing , Wang Dahui , Zhao Yanying
Published: January 2024

In this study, we have successfully demonstrated a high-energy subpicosecond Yb:YAG laser system based on chirped-pulse regenerative amplification. Our experimental results demonstrate a pulse energy of 3 mJ with a pulse duration of 829.8 fs and a repetition rate of 1 kHz. Additionally, we conducted an extensive investigation into the system’s recompression capability under various modulation and seeding conditions. Our findings suggest that the system can achieve effective recompression over a broad range of parameters, with the ability to compensate for a considerable degree of chirp. Our study provides valuable insights into the fundamental physic of high-energy laser systems and the performance characteristics of chirped-pulse regenerative amplification.
Exploring the Anticancer Potential of Traditional Thai Medicinal Plants: A Focus on Dracaena loureiri and Its Effects on Non-Small-Cell Lung Cancer
Authors: Huang Xiaomin , Arjsri Punnida , Srisawad Kamonwan , Yodkeeree Supachai , Dejkriengkraikul Pornngarm
Published: January 2024

Non-small-cell lung cancer (NSCLC) is renowned for its aggressive and highly metastatic nature. In recent years, there has been a surge in interest regarding the therapeutic potential of traditional medicinal plants. Dracaena loureirin (D. loureirin), Ficus racemosa Linn. (F. racemosa), and Harrisonia perforata (Blanco) Merr. (H. perforata) are prominent traditional medicinal herbs in Thailand, recognized for their diverse biological activities, including antipyretic and anti-inflammatory effects. However, their prospective anti-cancer properties against NSCLC remain largely unexplored. This study aimed to evaluate the anti-cancer attributes of ethanolic extracts obtained from D. loureiri (DLEE), F. racemosa (FREE), and H. perforata (HPEE) against the A549 lung adenocarcinoma cell lines. Sulforhodamine B (SRB) assay results revealed that only DLEE exhibited cytotoxic effects on A549 cells, whereas FREE and HPEE showed no such cytotoxicity. To elucidate the anti-cancer mechanisms of DLEE, cell cycle and apoptosis assays were performed. The findings demonstrated that DLEE inhibited cell proliferation and induced cell cycle arrest at the G0/G1 phase in A549 cells through the downregulation of key cell cycle regulator proteins, including cyclin D1, CDK-2, and CDK-4. Furthermore, DLEE treatment facilitated apoptosis in A549 cells by suppressing anti-apoptotic proteins (Bcl-2, Bcl-xl, and survivin) and enhancing apoptotic proteins (cleaved-caspase-3 and cleaved-PARP-1). In summary, our study provides novel insights into the significant anti-cancer properties of DLEE against A549 cells. This work represents the first report suggesting that DLEE has the capability to impede the growth of A549 lung adenocarcinoma cells through the induction of apoptosis.
Growth, Physiological, and Biochemical Variations in Tomatoes after Infection with Different Density Levels of Meloidogyne enterolobii
Authors: Sikandar Aatika , Wu Fangcao , He Heliang , Ullah Rana Muhammad Kaleem , Wu Haiyan
Published: January 2024

Meloidogyne enterolobii is an extremely important plant parasitic nematode. Tomato (Solanum lycopersicum) is an essential worldwide vegetable, and M. enterolobii poses a major threat to its production. The present research investigated the effects of different levels of inoculum density of M. enterolobii (100, 500, 1000, 1500, and 2000 second-stage juveniles (J2s)/plant) on tomato growth, physiological, and biochemical changes at 7, 14, 21, and 28 days post-inoculation (dpi). The negative impact of M. enterolobii on plants gradually increased when the inoculum level increased. Therefore, M. enterolobii population densities (500–2000 J2s/plant) significantly (p < 0.05) reduced plant growth, photosynthetic pigmentation, gas exchange, and chlorophyll fluorescence compared to control plants, while the low population density (100 J2s/plant) showed very little influence. Furthermore, plants with the highest M. enterolobii inoculum (2000 J2s/plant) exhibited a greater number of egg masses and galls. The inoculum densities of M. enterolobii exhibited a notable correlation with the significant elevation of both malondialdehyde (MDA) and hydrogen peroxide (H2O2) levels, which are recognized as very detrimental stresses in plants. Similarly, a rise in the activity of several defensive antioxidant enzymes, namely superoxide dismutase (SOD), catalase (CAT), and peroxidase (POD), indicates the defensive mechanism used to combat the oxidative destruction produced by M. enterolobii. The specific activity of glutathione (GSH) and ascorbate (ASA) increased as potent antioxidant defense molecules in response to induced oxidative damage. In addition, our findings also demonstrated that the highest population density (2000 J2s/plant) increased the secondary metabolites responsible for scavenging oxidative stress in the plants. However, further research is required to explore the underlying reasons for this phenomenon and to develop efficient chemical or biocontrol strategies for managing M. enterolobii.
The Combining Ability and Heterosis Analysis of Sweet–Waxy Corn Hybrids for Yield-Related Traits and Carotenoids
Authors: Prai-anun Kanyarat , Jirakiattikul Yaowapha , Suriharn Khundej , Harakotr Bhornchai
Published: January 2024

Improving sweet–waxy corn hybrids enriched in carotenoids via a hybrid breeding approach may provide an alternative cash crop for growers and provide health benefits for consumers. This study estimates the combining ability and heterosis of sweet–waxy corn hybrids for yield-related traits and carotenoids. Eight super sweet corn and three waxy corn lines were crossed to generate 24 F1 hybrids according to the North Carolina Design II scheme, and these hybrids were evaluated across two seasons of 2021/22. The results showed that both additive and non-additive genetic effects were involved in expressing the traits, but the additive genetic effect was more predominant. Most observed traits exhibited moderate to high narrow-sense heritability. Three parental lines, namely the ILS2 and ILS7 females and the ILW1 male, showed the highest positive GCA effects on yield-related traits, making them desirable for developing high-yielding hybrids. Meanwhile, five parental lines, namely the ILS3, ILS5, and ILS7 females and the ILW1 and ILW2 males, were favorable general combiners for high carotenoids. A tested hybrid, ILS2 × ILW1, was a candidate biofortified sweet–waxy corn hybrid possessing high yields and carotenoids. Heterosis and per se performance were more positively correlated with GCAsum than SCA, indicating that GCAsum can predict heterosis for improving biofortified sweet–waxy corn hybrid enriched in carotenoids. The breeding strategies of biofortified sweet–waxy corn hybrids with high yield and carotenoid content are discussed.
Improving the Quality of Tantalum Cylindrical Deep-Drawn Part Formation Using Different Lubricating Media-Coated Dies
Authors: Xu Teng , Dou Shihao , Su Mingwu , Huang Jianbin , Zhu Ningyuan , Yu Shangpang , Zhu Likuan
Published: January 2024

Lubrication is one of the key factors to improve metal-forming quality. In the process of deep drawing, seizing tumors easily occur on the contact surfaces between the tantalum metal and the mold, which greatly affects the forming quality of the deep-drawn parts. Quality-forming quality problems that occur during the deep drawing of tantalum metal are studied from the perspective of lubrication in this paper. Three lubrication media, caster oil, PE (polyethylene) film, and DLC (Diamond Like Carbon) film, were adopted in the deep drawing of tantalum cylindrical cups. A universal testing machine and microscope were used to investigate the effect of lubrication media on the limit-drawing ratio, maximum forming force, and surface topography quality during the deep drawing process of the tantalum sheet. The results reveal that the lubrication of the PE film and DLC film can greatly improve the forming quality of the tantalum metal sheet, in which the DLC film has higher wear resistance and lower friction coefficient and can be used as the lubricating medium in the industrial forming process of tantalum deep-drawn parts.
Digital Twin Enabled Process Development, Optimization and Control in Lyophilization for Enhanced Biopharmaceutical Production
Authors: Juckers Alex , Knerr Petra , Harms Frank , Strube Jochen
Published: January 2024

Digital twins have emerged as a powerful concept for real-time monitoring and analysis, facilitating Quality by Design integration into biopharmaceutical manufacturing. Traditionally, lyophilization processes are developed through trial-and-error, incorporating high security margins and inflexible process set points. Digital twins enable the integration of adaptable operating conditions and implementation of automation through Advanced Process Control (APC) with Process Analytical Technology (PAT) and validated physicochemical models that rely on heat and mass transfer principles, allowing us to overcome the challenges imposed by the lyophilization process. In this study, a digital twin for freeze-drying processes is developed and experimentally validated. Using the digital twin, primary drying conditions were optimized for controlled nucleation and annealing methods by carrying out a few laboratory tests beforehand. By incorporating PAT and modeling, the digital twin accurately predicts the product’s temperature and drying endpoint, showing smaller errors than the experiments. The digital twin significantly increases productivity by up to 300% while reducing the costs by 74% and the Global Warming Potential by 64%.
Spatio-Temporal Evolution of Loading and Deformation of Surface Gas Pipelines for High-Intensity Coalbed Mining and Its Integrity Prediction Methodology
Authors: Xu Yingnan , Liang Shun , Liang Xu , Yang Biao , Shi Zhuolin , Wu Chengle , Shen Jinhang , Yang Miao , Ma Yindou , Xu Pei
Published: January 2024

In recent years, the integrity of the gas pipeline in the coal-gas co-mining subsidence area has become a critical problem, restricting the safe and efficient mining of coal resources. This paper establishes a theoretical model for the safety prediction of gas pipelines in mining subsidence areas based on elastic free theory, constructs a 3D model of pipe-sand soil by using ABAQUS simulation software (2021), analyzes the characteristics of ground surface and pipeline settlement combined with the measured data on-site, and reveals the temporal and spatial evolution law of the pipeline load and deformation under the condition of diagonal intersections of the pipeline and high-strength mining working face. The results show that during the mining cycle, the pipe and the sandy soil body experienced the stage of cooperative deformation, the stage of increasing non-cooperative deformation, and the stage of weakening non-cooperative deformation; the pipe body is most vulnerable to yield failure in the circumferential direction of 180°, 45°, 225°, and 0°; the relative deformation rate of the pipe experienced a slow and rapid increase in the stage, and tends to flatten out when the advancement length is about 1.5–2 times the distance at the taken cross-section. The study’s results are conducive to accurately predicting the pipe failure orientation under high-intensity mining conditions in coal seams, improving the diagnostic efficiency of pipes, and optimizing the advancement speed of the working face.
Transition Metal Complexes with Amino Acids, Peptides and Carbohydrates in Catalytic Asymmetric Synthesis: A Short Review
Authors: Titova Yuliya
Published: January 2024

The present review is devoted to the application of transition metal complexes with such ligands as amino acids, peptides and carbohydrates in catalysis. The literature published over the past 20 years is surveyed. Among the distinctive features of these ligands are their versatility, optical activity, stability and availability. Furthermore, depending on the specific synthetic task to be solved, these ligands open up almost infinite opportunity for modification. Largely thanks to their multifaceted reactivity, transition metal complexes with amino acids, peptides and carbohydrates can catalyze most of the known chemical reactions affording optically pure compounds. In this review, the emphasis is placed upon C(sp3)–H activation, cross-coupling and hydrogenation (including traditional hydrogenation in the presence of hydrogen gas and hydrogenation with hydrogen transfer) reactions. The choice is not accidental, since these reactions on the one hand display the catalytic versatility of the above complexes, and on the other hand, they are widely employed in industry.
The Influence of Wettability Effect and Adsorption Thickness on Nanoconfined Methane Phase Behavior: Vapor-Liquid Co-Existence Curves and Phase Diagrams
Authors: Wu Guodai , Zeng Chunlin , Cheng Lijun , Luan Jinhua , Zhang Ruigang , Chen Ziwei , Pang Yu , Sun Zheng
Published: January 2024

Research interest in the behavior of methane inside nanopores has been growing, driven by the substantial geological reserves of shale gas and coalbed methane. The phase diagram of methane in nanopores differs significantly from its bulk state, influencing its existing form and pertinent physical properties—such as density and viscosity—at specific pressures and temperatures. Currently, there is a lack of effort to understand the nanoconfinement effect on the methane phase diagram; this is a crucial issue that needs urgent attention before delving into other aspects of nanoconfined methane behavior. In this study, we establish a fully coupled model to predict the methane phase diagram across various scales. The model is based on vapor-liquid fugacity equilibrium, considering the shift in critical pressure and temperature induced by pore size shrinkage and adsorption-phase thickness. Notably, our proposed model incorporates the often-overlooked factor of capillary pressure, which is greatly amplified by nanoscale pore size and the presence of the adsorption phase. Additionally, we investigated the impact of surface wettability, correlated to capillary pressure and the shift in critical properties, on the methane phase diagram. Our results indicate that (a) as pore size decreases, the methane phase diagram becomes more vertical, suggesting a transition from a gaseous to a liquid state for some methane molecules, which is contrary to the conventional phase diagram; (b) enhancing surface wettability results in a more vertical phase diagram, with the minimum temperature corresponding to 0 MPa pressure on the phase diagram, increasing by as much as 87.3%; (c) the influence of capillary pressure on the phase diagram is more pronounced under strong wettability conditions compared to weak wettability, and the impact from the shift in critical properties can be neglected when the pore size exceeds 50 nm.
Driving Strategies for Omnidirectional Mobile Robots with Offset Differential Wheels
Authors: Badia Torres Joan , Perez Gracia Alba , Domenech-Mestres Carles
Published: January 2024

In this work, we present an analysis of, as well as driving strategies and design considerations for, a type of omnidirectional mobile robot: the offset-differential robot. This system presents omnidirectionality while using any type of standard wheel, allowing for applications in uneven and rough terrains, as well as cluttered environments. The known fact that these robots, as well as simple differential robots, have an unstable driving zone, has mostly been dealt with by designing driving strategies in the stable zone of internal dynamics. However, driving in the unstable zone may be advantageous when dealing with rough and uneven terrains. This work is based on the full kinematic and dynamic analysis of a robot, including its passive elements, to explain the unexpected behaviors that appear during its motion due to instability. Precise torque calculations taking into account the configuration of the passive elements were performed for better torque control, and design recommendations are included. The stable and unstable behaviors were characterized, and driving strategies were described in order to achieve the desired performance regarding precise positioning and speed. The model and driving strategies were validated through simulations and experimental testing. This work lays the foundation for the design of better control strategies for offset-differential robots.
Exploring Spatial and Temporal Dynamics of Red Sea Air Quality through Multivariate Analysis, Trajectories, and Satellite Observations
Authors: Mitra Bijoy , Hridoy Al-Ekram Elahee , Mahmud Khaled , Uddin Mohammed Sakib , Talha Abu , Das Nayan , Nath Sajib Kumar , Shafiullah Md , Rahman Syed Masiur , Rahman Muhammad Muhitur
Published: January 2024

The Red Sea, a significant ecoregion and vital marine transportation route, has experienced a consistent rise in air pollution in recent years. Hence, it is imperative to assess the spatial and temporal distribution of air quality parameters across the Red Sea and identify temporal trends. This study concentrates on utilizing multiple satellite observations to gather diverse meteorological data and vertical tropospheric columns of aerosols and trace gases, encompassing carbon monoxide (CO), nitrogen dioxide (NO2), sulfur dioxide (SO2), and ozone (O3). Furthermore, the study employs the Hybrid Single-Particle Lagrangian Integrated Trajectory (HYSPLIT) model to analyze the backward trajectory of air mass movement, aiding in the identification of significant sources of air pollutants. A principal component analysis (PCA) with varimax rotation is applied to explore the relationship and co-variance between the aerosol index (AI), trace gas concentrations, and meteorological data. The investigation reveals seasonal and regional patterns in the tropospheric columns of trace gases and AI over the Red Sea. The correlation analysis indicates medium-to-low positive correlations (0.2 < r < 0.6) between air pollutants (NO2, SO2, and O3) and meteorological parameters, while negative correlations (−0.3 < r < −0.7) are observed between O3, aerosol index, and wind speed. The results from the HYSPLIT model unveil long-range trajectory patterns. Despite inherent limitations in satellite observations compared to in situ measurements, this study provides an encompassing view of air pollution across the Red Sea, offering valuable insights for future researchers and policymakers.
Deception Velocity-Based Method to Discriminate Physical Targets and Active False Targets in a Multistatic Radar System
Authors: Li Qiang , Guo Yumei , Zhang Peng , Xu Hong , Zhang Linrang , Chen Zhanye , Huang Yan
Published: January 2024

Due to the silent operation of the receiver station in a multistatic radar system, it is difficult for the jammer to generate the cooperative active deception target for the multistatic radar system. Making use of the spatial diversity property, a data level fusion method is proposed to counter the active deception jamming in this paper. According to the spatial correlation difference in physical target and active false target motion states, the deception velocity of the physical target, which is obtained by the radial velocity of each receiver, obeys the Gaussian distribution with zero mean, and the one of the active false target obeys the Gaussian distribution with the mean being its true deception velocity. Based on this fact, the active false target and physical target are discriminated by the deception velocity testing. The proposed deception velocity-based (DVB) method can keep a constant misjudgment probability for physical targets and discriminate active false targets effectively, especially in large deception velocity cases. The simulation verifies the feasibility and validity of the proposed discrimination method. Moreover, the proposed method can be combined with the location information association method to enhance the ability to discriminate the range–velocity joint deception of false targets.
Robot Grasp Planning: A Learning from Demonstration-Based Approach
Authors: Wang Kaimeng , Fan Yongxiang , Sakuma Ichiro
Published: January 2024

Robot grasping constitutes an essential capability in fulfilling the complexities of advanced industrial operations. This field has been extensively investigated to address a range of practical applications. However, the generation of a stable grasp remains challenging, principally due to the constraints imposed by object geometries and the diverse objectives of the tasks. In this work, we propose a novel learning from demonstration-based grasp-planning framework. This framework is designed to extract crucial human grasp skills, namely the contact region and approach direction, from a single demonstration. Then, it formulates an optimization problem that integrates the extracted skills to generate a stable grasp. Distinct from conventional methods that rely on learning implicit synergies through human demonstration or on mapping the dissimilar kinematics between human hands and robot grippers, our approach focuses on learning the intuitive human intent that involves the potential contact regions and the grasping approach direction. Furthermore, our optimization formulation is capable of identifying the optimal grasp by minimizing the surface fitting error between the demonstrated contact regions on the object and the gripper finger surface and imposing a penalty for any misalignment between the demonstrated and the gripper’s approach directions. A series of experiments is conducted to verify the effectiveness of the proposed algorithm through both simulations and real-world scenarios.
Optimizing Sensor Placement for Temperature Mapping during Ablation Procedures
Authors: Santucci Francesca , Nobili Martina , De Tommasi Francesca , Lo Presti Daniela , Massaroni Carlo , Schena Emiliano , Oliva Gabriele
Published: January 2024

Accurately mapping the temperature during ablation is crucial for improving clinical outcomes. While various sensor configurations have been suggested in the literature, depending on the sensors’ type, number, and size, a comprehensive understanding of optimizing these parameters for precise temperature reconstruction is still lacking. This study addresses this gap by introducing a tool based on a theoretical model to optimize the placement of fiber Bragg grating sensors (FBG) within the organ undergoing ablation. The theoretical model serves as a general framework, allowing for adaptation to various situations. In practical application, the model provides a foundational structure, with the flexibility to tailor specific optimal solutions by adjusting problem-specific data. We propose a nonlinear and nonconvex (and, thus, only solvable in an approximated manner) optimization formulation to determine the optimal distribution and three-dimensional placement of FBG arrays. The optimization aims to find a trade-off among two objectives: maximizing the variance of the expected temperatures measured by the sensors, which can be obtained from a predictive simulation that considers both the type of applicator used and the specific organ involved, and maximizing the squared sum of the distances between the sensor pairs. The proposed approach provides a trade-off between collecting diverse temperatures and not having all the sensors concentrated in a single area. We address the optimization problem through the utilization of approximation schemes in programming. We then substantiate the efficacy of this approach through simulations. This study tackles optimizing the FBGs’ sensor placement for precise temperature monitoring during tumor ablation. Optimizing the FBG placement enhances temperature mapping, aiding in tumor cell eradication while minimizing damage to surrounding tissues.
A Spin Valve-Based Rhombus-Shaped Micro-Object Implementing a Full Wheatstone Bridge
Authors: Milyaev Mikhail , Naumova Larisa , Germizina Anastasiya , Chernyshova Tatyana , Pavlova Anastasia , Krinitsina Tatiana , Proglyado Vyacheslav , Ustinov Vladimir
Published: January 2024

Spin valves with a synthetic antiferromagnet were fabricated via magnetron sputtering. It was shown that the fabricated spin valve layers had a perfect microstructure and smooth interfaces, and therefore, an RKKY interaction dominated in the coupling of the ferromagnetic layers separated by a copper spacer. Rhombus-shaped micro-objects were fabricated from a single spin valve film. The thermomagnetic treatment procedure was found to form unidirectional anisotropy in the micro-object such that the values of the exchange bias fields in the rhombus’ nonparallel sides were opposite in sign. For the CoFeNi/Ru/CoFeNi synthetic antiferromagnet, we determined the differences between the ferromagnetic layer thicknesses at which the thermomagnetic treatment formed the same exchange bias all over each rhombus’ side. We also fabricated a sensor element in which each side of the rhombus was the shoulder of a Wheatstone bridge. After the thermomagnetic treatment procedure, each shoulder worked as an active magnetosensitive element, enabling the device to operate as a full Wheatstone bridge. The sensor output exhibited a step shape, high sensitivity to field changes, and significant magnetic hysteresis. Such characteristics are suitable for switching devices.
Activity Detection in Indoor Environments Using Multiple 2D Lidars
Authors: Bouazizi Mondher , Mora Alejandro Lorite , Feghoul Kevin , Ohtsuki Tomoaki
Published: January 2024

In health monitoring systems for the elderly, a crucial aspect is unobtrusively and continuously monitoring their activities to detect potentially hazardous incidents such as sudden falls as soon as they occur. However, the effectiveness of current non-contact sensor-based activity detection systems is limited by obstacles present in the environment. To overcome this limitation, a straightforward yet highly efficient approach involves utilizing multiple sensors that collaborate seamlessly. This paper proposes a method that leverages 2D Light Detection and Ranging (Lidar) technology for activity detection. Multiple 2D Lidars are positioned in an indoor environment with varying obstacles such as furniture, working cohesively to create a comprehensive representation of ongoing activities. The data from these Lidars is concatenated and transformed into a more interpretable format, resembling images. A convolutional Long Short-Term Memory (LSTM) Neural Network is then used to process these generated images to classify the activities. The proposed approach achieves high accuracy in three tasks: activity detection, fall detection, and unsteady gait detection. Specifically, it attains accuracies of 96.10%, 99.13%, and 93.13% for these tasks, respectively. This demonstrates the efficacy and promise of the method in effectively monitoring and identifying potentially hazardous events for the elderly through 2D Lidars, which are non-intrusive sensing technology.
Investigating the Combined Effects of Fascial Distortion Model Manual Therapy and Balance–Strength Training in Individuals with Chronic Ankle Instability
Authors: Mohammadi Amin , Sakhtemani Seyed Ehsan , Trimmel Lukas , Petricsevics Krisztina , Makai Alexandra , Zsenak Istvan , Melczer Csaba , Tardi Péter Sándor
Published: January 2024

Background: The Fascial Distortion Model (FDM) is a relatively new manual therapy approach in the field of musculoskeletal physical therapy, and its potential effectiveness in treating chronic ankle instability (CAI) remains unexplored. Methods: A randomized controlled trial with 23 participants was conducted. Patients were randomly assigned to either the FDM + balance–strength training (BST) group (n = 8), receiving extra FDM sessions weekly in addition to two sessions of BST, or the BST group (n = 7). Healthy controls (n = 8) did not receive any treatment and participated only in pre- and post-test measurements. Objective measurements including Y-Balance Test Lower Quarter (YBT-LQ), Flamingo Balance Test (FBT), Weight-Bearing Lunge Test (WBLT), ankle joint range of motion (ROM), and Cumberland Ankle Instability Tool (CAIT) were recorded at baseline and the end of the intervention. The results demonstrated significant differences between the FDM + BST and BST groups for supination ROM (p = 0.008) and similarly for WBLT (p = 0.041), FBT (p = 0.40), YBT-LQ (p = 0.023), and CAIT score (p = 0.008). Moreover, while both groups demonstrated significant improvement at the post-test compared with their pre-test for plantarflexion and pronation ROM, WBLT, and CAIT score, the FDM + BST group demonstrated significant improvements in supination ROM, FBT, and YBT-LQ. Conclusion: Our study suggests that the addition of FDM concepts to a BST may lead to enhanced improvements in ankle ROM, static and dynamic balance, and self-reported outcomes in individuals with CAI compared to BST.
Modeling of Particle Size Distribution in the Presence of Flocculant
Authors: Fedorova Elmira , Pupysheva Elena , Morgunov Vladimir
Published: January 2024

This study presents a mathematical description of the solid fraction aggregation process in the presence of a flocculant and its result. The basis is a population balance equation. The model is realized in Python language. Verification was carried out using red mud from the investigated enterprise; Flomin AL P 99 VHM was used as a flocculant. The mean square deviation for the parameter “mean aggregate diameter” is equal to 19.88 μm. The time required for the model calculation is about 3 min. The time spent on modeling depends on the number of calculation channels. In this study, 40 channels (20 with PSD source data, and 20 with empty values required for the calculation) were used for the calculation. The time spent on the model calculation is much shorter than the inertia via each of the communication channels for the studied symmetric radial type thickener. A user interface is developed, where the input parameters are the initial pulp particle size distribution, viscosity and density of pulp in the thickener, particle surface area, concentration and flow rate of flocculant, concentration of solid particles, inner diameter and height of the feed well, and simulation time. The result of the simulation is particle size distribution in the feed well of the washer and the mean flocculus diameter.