bluuebunny/crossref_metadata_2025 huggingface dataset:
An exploratory analysis of probable role of Pathya and Apathya in skin disease
Authors: Amit Choudhary  , Yadav Minu , Sunita Dudi  , Sachin Sharma  , Chandan Singh  , Manoj Kumar Adlakha
Published: June 2023

Every living and non-living being in this universe is composed of five basic elements, the Pancha Mahabhuta. The Panch

Every living and non-living being in this universe is composed of five basic elements, the Pancha Mahabhuta. The Pancha Mahabhuta components of the ingested food nourishes their respective tissue elements in the body. Ahara is the best of all medicines and is considered one among the Trayopsthamba. The main idea of Pathya Ahara and Vihara serves as the foundation for both the preventive and therapeutic components of Ayurveda. Ayurveda places a strong emphasis on fundamental dietary principles, or Ashtavidha Ahara Vidhi Visheshayatana. Skin is given due importance since time immemorial owning to the aesthetic value conferred upon it. Skin diseases are mainly described under the spectrum of Kushtha. Dietary modifications have hitherto received little attention in dermatological therapy. However, recent studies have discovered a strong link between various dermatological conditions and food. Ayurveda describes a wide range of etiological factors for dermatological disorders. Consumption of Ahara such as Ati-Lavana, Ati-Amla, Viruddhahara, Guru-Snigdha Annapana, Ajeernahara plays a significant role in the development of skin disease. Excessive intake of food items like Dadhi, fish with milk, Masha, Mulaka, Tila, Madya further contribute to Kushtha. In this article an attempt is made to highlight the probable role of Apathya and emphasize the scope of Pathya Ahara in the management of skin disease.

a Mahabhuta components of the ingested food nourishes their respective tissue elements in the body. Ahara is the best of all medicines and is considered one among the Trayopsthamba. The main idea of Pathya Ahara and Vihara serves as the foundation for both the preventive and therapeutic components of Ayurveda. Ayurveda places a strong emphasis on fundamental dietary principles, or Ashtavidha Ahara Vidhi Visheshayatana. Skin is given due importance since time immemorial owning to the aesthetic value conferred upon it. Skin diseases are mainly described under the spectrum of Kushtha. Dietary modifications have hitherto received little attention in dermatological therapy. However, recent studies have discovered a strong link between various dermatological conditions and food. Ayurveda describes a wide range of etiological factors for dermatological disorders. Consumption of Ahara such as Ati-Lavana, Ati-Amla, Viruddhahara, Guru-Snigdha Annapana, Ajeernahara plays a significant role in the development of skin disease. Excessive intake of food items like Dadhi, fish with milk, Masha, Mulaka, Tila, Madya further contribute to Kushtha. In this article an attempt is made to highlight the probable role of Apathya and emphasize the scope of Pathya Ahara in the management of skin disease.
INCREASING PROFITABILITY OF A MANUFACTURING COMPANY BY USING THE TOTAL PRODUCTIVE MAINTENANCE APPROACH: A REVIEW
Authors: Wardhani Angelia Kusuma , Risonarta Victor Yuardi
Published: June 2023

In the modern world, a company pays serious attention to productivity and efficiency. Several sectors in the manufacturing world are starting to carry out business transformation, particularly those leading to industry 4.0. This circumstance is driven by efforts to achieve higher productivity and efficient process, mainly after being economically hit by the Covid-19 pandemic. To maintain efficiency, a manufacturing company should maintain its machine and equipment. Total productive maintenance is a system based on the concept of preventive and predictive maintenance. It is designed to prevent losses resulting from many factors, e.g. work stoppages due to failures and adjustments, speed losses due to minor stops and speed reductions, and losses due to defects. The total productive maintenance also provides a tool to measure the level of effectiveness of a machine, i.e. overall equipment effectiveness. This review paper focuses on the application of total productive maintenance and overall equipment effectiveness in determining the effectiveness of equipment and eliminating the factors affecting the effectiveness of the equipment.
Fortifying Health Care Intellectual Property Transactions With Blockchain
Authors: Liang Huan-Wei , Chu Yuan-Chia , Han Tsung-Hsien
Published: June 2023

Background

Intellectual property (IP) is a substantial competitive advantage in the health care industry. However, the COVID-19 pandemic highlighted the need for open innovation and collaboration for the greater good. Despite this, the industry faces challenges with innovation owing to organizational and departmental barriers. A secure platform is necessary to facilitate IP sharing without compromising the rights of IP owners.

Objective

This study proposes a blockchain-based framework to secure IP transactions in health care and bring social impact.

Methods

This study reviews existing researches, publications, practical cases, firm and organization websites, and conferences related to blockchain technology, blockchain in health care, blockchain in IP management, IP pledge research, and practice of IP management blockchain. The platform architecture has 7 components: pledgers, advanced research technology (ART), IP pledge platforms, IP databases, health care research, seeking ART, and transaction condition setting. These components work together seamlessly to support the sharing and pledging of ART and knowledge, while ensuring the platform’s transparency, security, and trust.

Results

The open IP pledge framework can promote technology dissemination and use, reduce research and development costs, foster collaboration, and serve the public interest. Medical organizations’ leadership and support and active participation from stakeholders are necessary for success. By leveraging blockchain technology, the platform ensures tamper-proof and transparent transactions and protects the rights of IP owners. In addition, the platform offers incentive mechanisms through pledge tokens that encourage stakeholders to share their ART and contribute to the platform.

Conclusions

Overall, the proposed framework can facilitate technological innovation, tackle various challenges, and secure IP transactions. It provides a secure platform for stakeholders to share their IP without compromising their rights, promoting collaboration and progress in the health care industry. The implementation of the framework has the potential to revolutionize the industry’s approach to innovation, allowing a more open and collaborative environment driven by the greater good.
Teledermatology as a care collaborative and triage model for improving specialist access and efficiency of dermatological care in Singapore. (Preprint)
Authors: Heng Yee Kiat , Kong Jing Wen , Chong Phui-Nah , Tan Suat Hoon
Published: June 2023

BACKGROUND

In Singapore, National Skin Centre (NSC) is the main dermatology centre in the public healthcare system. However long appointment waiting times have resulted from heavy referral load.
Family Physicians (FPs) who have limited dermatology training may face uncertainty in managing skin conditions and have a low threshold to refer cases to a specialist centre.

OBJECTIVE

To develop a teledermatology network within the same healthcare cluster to reduce NSC appointment waiting time and assist FPs in managing dermatology cases

METHODS

We developed collaborative care model with teledermatology support involving NSC and National Healthcare Group Polyclinics (NHGP). For each polyclinic, designated clinician leads with additional dermatology training (‘Derm Champs’ or DCs) performed screening of referrals and conducted Store-and-Forward teleconsultations, if needed, with NSC dermatologists for management or triaging.

RESULTS

Over 2 years, polyclinic DCs screened 2258 cases, of which 28.6% were managed in primary care, 67.3% were referred to NSC and 4.0% were referred to emergency or other departments. Almost half of 322 tele-consulted cases avoided onward referral. NSC appointment waiting times were reduced within 6 months of service introduction.

CONCLUSIONS

Teledermatology used in the context of a collaborative care network can expedite and improve patient care, helping to triage and reduce specialist referrals. Teledermatology is valuable even in a small country like Singapore with a well-developed healthcare system and will probably be increasingly utilised with technological advances, even in the post-COVID 19 pandemic era.
Readability and Health Literacy Scores for ChatGPT-Generated Dermatology Public Education Materials: Cross-Sectional Analysis of Sunscreen and Melanoma Questions (Preprint)
Authors: Roster Katie , Kann Rebecca B , Farabi Banu , Gronbeck Christian , Brownstone Nicholas , Lipner Shari R
Published: June 2023

UNSTRUCTURED

N/A
Concerns on Generalizability (Preprint)
Authors: Lin Yongjian
Published: June 2023

UNSTRUCTURED

N/A
In-Depth Analysis of the Professional Quality Problems and Solution Strategies of Children’s Dance Teachers
Authors: Duan MengShan
Published: June 2023

As China’s national strength is becoming more and more powerful, the material foundation of the people is generally rich, China’s dance art cause has appeared vigorous scene, especially under the strong support of national policies, the status of dance art has risen sharply. At the same time, a large number of children’s dance education classes have emerged inside and outside the school. However, under the competition of business model, the development of some dance education institutions begins to have many problems, etc. Children’s dance education methods are uneven, and the threshold of teachers is unclear. This paper will focus on the analysis of the chaos caused by the problem of teachers ‘professional quality in children’s dance education in China, put forward relevant basic strategies for such problems, and make efforts to get more scientific, systematic and comprehensive theoretical guidance in the development process of children’s dance education
Characterisation of several isolates of Fusarium oxysporum f. sp. elaeidis for the selection of fusarium-resistant oil palm varieties
Authors: Mva Armand Nsimi , Tengoua Fonguimgo Fabien , Adagoro Hawaou , Pueufo Edgar Roussel Wakam , Dooh Jules Patrice Ngoh
Published: June 2023

This work was aim to evaluate the pathogenicity and the level of aggressiveness of ten strains of Fusarium oxysporum f. sp. elaeidis (Foe) on palm oil seedlings susceptible to vascular wilt. For this purpose, the radial growth, sporulation and the morphological characteristics of ten strains of Foe from the farm palm of the Cameroon Development Corporation (South-west) were studied in vitro. In addition, 500 oil palm seedlings susceptible to vascular wilt and aged 5 months were distributed in a randomized complete block device, and inoculated with said strains. External symptoms of Fusarium wilt were observed on those seedlings and the correlation between these parameters was also investigated. The data collected in prenursery did not establish a significant difference in the aggressiveness of the isolates. However, regarding the pathogenicity, 7 strains have shown a high pathogenicity. As for the radial growth, strain F presented fastest growth was 8.12 cm in diameter, unlike the strainI whose growth was the lowest is 3.98 cm in diameter. The C strain is one that is abundantly sporulated126,5x105spores/ml; however, isolates B and J do not sporulate. No correlation was detected between the different parameters. But, considering the results obtained, the F and I strains could be the most aggressive and can potentially be used to test the timber yard of the specialized Centre for oil palm research of La DIBAMBA to select the most resistant to vascular wilt.
A complexidade da significação probatória
Authors: Da Silva Pereira Eliomar
Published: June 2023

O que queremos dizer com a asserção “está provado que”? O argumento principal deste artigo é que se trata de um problema de significação probatória, cuja devida compreensão passa pelo conceito central de intencionalidade, acerca do qual encontramos muitos problemas, precisamos distinguir dimensões semióticas e especificar uma constelação de noções lógicas. O objetivo deste artigo consiste em discutir essas questões, com base em uma abordagem que mobiliza argumentos da filosofia da mente e da linguagem, especialmente encontrados nas teorias de J. R. Searle. Ao final, esperamos tornar claro que a significação probatória, embora pressuponha uma mente e se encontre em linguagem processual, consiste em uma específica intencionalidade intermediária, que se pode beneficiar teoricamente das duas bases conceituais, e assim tornar evidente tudo que se supõe na asserção “está provado que”.
Modeling Forest Wildfires at regional scales
Authors: Graciano-Luna José de Jesús , Rodríguez-Flores Felipa de Jesús , Corral Rivas Sacramento , Návar José
Published: June 2023

Este artículo tiene por objetivos: (i) presentar, (ii) probar y (iii) validar un conjunto de técnicas matemáticas para predecir el número de incendios (No), la superficie incendiada (A), y la superficie promedio incendiada (AM), en bases anuales a escalas regionales. Una fuente de datos extensa proveniente de los bosques de coníferas de Durango se usó para ajustar (1970-2011) y validar (2012-2016) las técnicas de modelaje. La mayoría de los modelos probabilísticos y estocásticos explican menos del 70% de la varianza de los incendios. Sin embargo, el método de teleconecciones que emplea variables a escala oceánica y a escala local del hidroclima aumentó el nivel de precisión hasta cerca del 80% de la varianza total para ambas bases de datos. Los resultados muestran la complejidad de los factores que interactúan, incluyendo los procesos estocásticos y los físicos que hacen que las técnicas de predicción sean modificadas substancialmente. Por estas razones, se propone un modelo más físicamente basado y también un modelo conceptual más comprensivo. El modelo conceptual requiere del uso de todas las técnicas presentadas en este reporte, incluyendo los modelos probabilísticos, estocásticos y físicos en la parameterización de los diferentes submodelos. El uso del modelo conceptual además de sus técnicas de simulación Monte Carlo extraerían los escenarios futuros mas probables en la predicción del riesgo de incendios forestales severos en bosques templados del mundo.
Assessment of Indoor/outdoor Particulate Matter in Residential Building: Tehran Metropolis, Iran
Authors: Oroji Balal
Published: June 2023

La calidad del aire interior y la predicción de los niveles de contaminación interior se han convertido en temas más importantes para los riesgos para la salud. Esta investigación se investigará la proporción de la concentración de partículas dentro y fuera de las casas residenciales en Teherán. El muestreo de material particulado (PM) se realizó en cuatro temporadas desde agosto de 2020 hasta julio de 2021. Se seleccionaron cuatro estaciones como estaciones de muestreo fijas y el tiempo de muestreo varió de 6 horas a 12 horas. Debido al riesgo de partículas finas y la posibilidad de su impacto en la salud humana, en este estudio se examinaron PM 0.4 y PM 2.5 . Para el muestreo se utilizó un amortiguador virtual de etapas múltiples que atrapa partículas en placas de acero con un flujo de aire constante. Se utilizaron los métodos Microscopio Electrónico de Barrido (SEM) y Espectrometría de Masas de Plasma Acoplado Inductivamente (ICP-MS) para estudiar el tamaño, la morfología y la composición química y analizar la concentración total de material particulado (PM). Los resultados mostraron que en la mayoría de las estaciones, la penetración de partículas exteriores en el edificio en la estación fría fue mayor que en la estación cálida. Debido al uso de ventilación natural en la mayoría de los edificios residenciales del área de estudio, la relación I/O de PM 2.5 y PM 0.4 fue en promedio superior a 0.752. En algunas estaciones en marzo, abril y mayo, la relación I/O fue superior a 0.965. De acuerdo con estos resultados, en el área oriente, la exposición a material particulado (PM) con un diámetro menor a 0.4 µm fue mayor que en otras áreas. Asimismo, los resultados mostraron que el efecto promedio del factor de ventilación durante el año fue del orden del 38.4%. En tanto, esta cantidad fue de 19.4 y 13% para los factores de cocción y actividad, respectivamente. El efecto promedio de los factores de vida del edificio y tabaquismo fue de 7.6 y 21.6%, respectivamente. Los resultados del método SEM mostraron que la penetración de contaminantes en el exterior del edificio tiene un gran efecto sobre la concentración de partículas en el interior.
Influence of Non-Woven Geotextile Over Chemically Stabilized Soil in Controlling Erosion
Authors: Varsha R. , Jeyapriya S. P.
Published: June 2023

Abstract: Soil erosion is the most significant hazard in sloping terrain. It affects the hilly regions by the loss of top layer of the soil. Soil erosion is mainly induced by rainfall. As the surface runoff flows with high velocity, the detachment of soil particles takes place and it moves down slope. It causes instability and leads to slope failure. The soil erosion depends on erodibility, rainfall erosivity and spatial variability. Non-woven geotextile has the interlocking fibers which retain the fine soil particles and allow water to pass through the fabric. In this study, non-woven geotextile is used over chemically stabilized soil to control the erosion. The stabilizers used are Guar gum powder and Magnesium Stearate powder. Erosion tests are conducted in the slope model for maximum hourly rainfall intensities of 60mm/hr and 70mm/hr on an inclined slope having inclination of 20°. The erosion rates for the slope wherein geotextile is used as reinforcement on soil treated with Guar gum powder in the slope model for rainfall intensities 60mm/hr and 70mm/hr are 2112g/m²/hr and 2798g/m²/hr respectively. Similarly, the same soil slope model in which the stabilizer used as Magnesium Stearate and reinforced with geotextile sheet and for the same rainfall of 60mm/hr and 70mm/hr intensities produced reduction in erosion rate of 1950g/m²/hr and 2312g/m²/hr respectively. The results show, that the erosion rate decreased with the use of geotextile on chemically stabilized soil with Magnesium Stearate when compared to the other method
Lighting Automation
Authors: S R Chaitrashree
Published: June 2023

Abstract: In most of the educational institutions, the significant amount of energy is spent for illuminating the classrooms and for switching the fans, computers and so on. Sometimes due to unnecessary consumption of energy the energy costs may rise. practices. In order to minimise the energy consumption or to avoid energy waste during unoccupied and daylight hours ,here more efficient equipment is designed for utilization of improved lighting design Here we have established a lighting control system in which the light circuits and fans in classroom remain Off in the absence of students and switches on in their presence. When student enter classroom , Infrared energy emitted from the person activates the IR sensor and the aurdino acts as power saving device according to relay operations. By using IR Sensor is detected the relays are triggered and the fan and lights are switched On. Measuring the brightness of the cl motion LDR Sensor for assroom and also a sensor is used for the measuring the temperature, if the temperature is above 25°C the fans will be turned ON.
Design and Simulation of a High Gain Boost Converter with Reduced Input Current Ripple
Authors: Banerjee Debadyuti
Published: June 2023

Abstract: This paper proposes a high gain novel DC- DC converter. According to this topology gain of the converter can be improved more than a boost converter without using any transformer. In this topology it is possible to increases the gain of the converter without increasing the current ripple in the input current. This proposed topology is capable to reduce the voltage stress of the switches. Implementation of non-isolated topology eliminates the need of the transformer and reduces the magnetic size. The maximum duty restriction problem can be reduced by the higher gain of this proposed converter. The ripple reduction in the input current increases the life of energy storage system.
Influence of factors on filtration regime of an earth dam under headwater drawdown
Authors: Aniskin Nikolai A. , Stupivtsev Andrey V.
Published: June 2023

Introduction. As the statistics of observations of groundwater retaining structures shows, one of the most significant factors of emergencies in these structures is the occurrence of filtration deformations in the dam body. This often results in the appearance of moves of concentrated filtration. The occurrence of these phenomena can be provoked by a rapid decrease of the headwater level known as reservoir drawdown. It can be caused either by the technological requirements of the operation of the hydraulic unit or by the occurrence of an emergency situation. Modern design standards require mandatory consideration of the case of rapid drawdown with an assessment of the filtration regime and stability of the structure.

Materials and methods. The results of numerical studies of unsteady filtration in a homogeneous earth dam under reservoir drawdown are considered. Numerical studies were carried out on the basis of the finite element method using the PRAXIS software package. Test calculations were carried out, which showed the reliability of the results obtained. The influence of the soil filtration coefficient of the dam, the rate of drawdown and the slope of the structure on the change in the position of the depression curve and the value of the maximum pressure gradient is analyzed.

Results. For the considered variants of earth dams with different characteristics, the parameters of the filtration flow are obtained when the headwater level changes: the position of the depression curve and the values of the maximum pressure gradients. An assessment of the possibility of occurrence of filtration deformations of soils of the upper prism of the dam is given.

Conclusions. The use of the PLAXIS software package for solving problems of unsteady filtration under reservoir level changes allows to obtain reliable results that are well comparable with the results of other proven methods. At certain rates of runoff for soils of different permeability in the upper prism of an earth dam, large values of pressure gradients exceeding critical values may occur. This indicates the necessity to control the process of drawdown and the use of antifiltration measures.
Забытый сюжет из истории советского градостроительства: несостоявшийся Всесоюзный съезд ВОРСа по планировке социалистических городов (1931)
Authors: Старостенко Юлия
Published: June 2023

центре внимания статьи находится сюжет из истории советского градостроительства рубежа 1920-х – 1930-х годов, ранее не попадавший в поле зрения исследователей, а именно – замысел Всероссийского общества рационализаторов строительства (ВОРС) по проведению в начале 1931 года первого Всесоюзного съезда по планировке социалистических городов. На основании материалов малоизвестных сегодня периодических изданий того времени и немногочисленных документов ВОРСа из Государственного архива Российской Федерации (ГАРФ) в статье предпринята попытка восстановить в общих чертах историю создания и деятельности ВОРСа, прежде всего, в сфере градостроительства. Особое внимание уделено созданию. Сектора социалистической планировки и реконструкции городов СССР при Центральном правлении ВОРСа под руководством С.М. Горного и инициативе по проведению градостроительного съезда, который рассматривается в публикации в ряду других состоявшихся и несостоявшихся мероприятий такого рода 1900-х – 1930-х годов. Смысловым центром статьи являются доклады участников конференции ВОРСа (Э. Мая, В.Л. Орлеанского, И.А. Ильина и Главного геодезического управления ВСНХ СССР), проведённой в марте 1931 года в качестве альтернативы отложенному съезду.
Британские «архитектурные маршруты» русских посланников грозненской эпохи
Authors: Чекмарёв Владимир
Published: June 2023

Статья посвящена первым встречам русских посланников Ивана Грозного с британской архитектурой. В отличиеот довольно хорошо исследованных русско-итальянских связей в области архитектуры, русско-английским художественнымконтактам этого периода до сих пор уделялось мало внимания. Тем не менее именно в это время закладывается основамноговековых двусторонних связей в целом ряде областей, в том числе и в архитектуре. Полное отсутствие  разработанности данной темы как в отечественной, так и в зарубежной специальной литературе определяет актуальность нашего исследования. Вместе с тем сохранившиеся краткие упоминания в английских источниках, Статейные списки, архивные источники и исследовательские работы всё же позволяют проследить, в каких городах им удалось побывать и с какими архитектурными памятниками воочию столкнуться.
Архитектура в традиционной культуре: строительство здания, его отделка и обживание, старение и модернизация, сохранение и уничтожение
Authors: Бондаренко Игорь
Published: June 2023

Делается попытка соотнести существование произведения архитектуры с жизненными циклами, сопряжёнными с обычаями и ритуалами, присущими традиционной культуре. Мир изменился, но многое в нем остаётся от прошлого исохраняет свою действенность по инерции до сих пор. Новое строение «рождается» как неполноценное на первых порах ичуждое окружению. Его необходимо оформить, украсить и обжить. Постепенно оно «приживается», «набирает силу», «расцветает». Некоторые архитектурные объекты с годами становятся знаковыми, особо ценными, прославляющими свой город и страну. Им подражают как образцам-«родоначальникам». «Старение» таких зданий затормаживается заботами почитателей. Сакрализация устраняет власть времени. Другой вариант продления жизни здания – его модернизация, «омоложение». Обращение к архаическим воззрениям помогает различать смысл поверхностного поновления, «переодевания» сооружения и его коренной реконструкции, которую можно назвать «перерождением». А то, что отжило свой век, должно «умирать» – рушиться и исчезать с лица земли. Традиция требовала также уничтожать здания, в которых «завелась нечистая сила» и происходят несчастья. Осуществлялось и целенаправленное разрушение завоевателями ключевых построек покорённых народов. Рассмотрение данной темы призвано помочь дифференциации разнокачественных архитектурных составляющих исторической городской среды, что необходимо при её современных преобразованиях.
O não-lugar de mulheres-mães na educação: ingresso à docência e a permanência no ensino superior
Authors: Pizolati Audrei Rodrigo da Conceição
Published: June 2023

Este artigo analisa o não-lugar de mulheres-mães no campo da educação. Para tanto, recorre-se teórico e metodologicamente aos Estudos das Políticas Educacionais, Estudos de Gênero pós-estruturalistas e Estudos foucaultianos. Em um primeiro momento é realizado um recuo histórico no intuito de investigar o não-lugar de mulheres-mães na docência, cujas investigações se dão no âmbito da I Conferência Nacional de Educação (1927). Após, debate-se sobre o não-lugar dessas mulheres-mães no Ensino Superior e o direito a Educação que lhe és garantido por lei, mas não efetivado. Diante disso, conclui-se que o avanço nas políticas educacionais permitiu o acesso ao ensino para distintas classes sociais, entretanto essas “minorias” ainda carecem de políticas que possibilitem a permanência e o êxito em seu processo formativo, o que acomete todos os níveis da educação – básica, profissionalizante e superior.
Desenvolver e medir a competência global nos professores: Uma revisão sistemática
Authors: Sanz-Leal María , Gómez Martha Lucía Orozco , Villasante Ángel Llorente
Published: June 2023

A competência global ganhou destaque a partir de sua inclusão no PISA (Programme for International Student Assessment) 2018 e é o resultado de diferentes modelos de educação global que permitirá aos estudantes enfrentar os desafios da globalização. Para isso, é necessária uma formação do professorado nesta competência e em seu ensino. Este estudo procura saber: a) o que entendemos por docentes globalmente competentes? b) como podemos melhorar esta competência? e c) como podemos avaliá-la? Através de uma revisão sistemática, 35 estudos foram compilados das bases de dados Scopus, Eric, e Web of Science. A análise mostra que a competência pedagógica global envolve dois aspectos: a competência pessoal e a competência pedagógica. Por sua vez, fornece vários programas de formação docente e diferentes metodologias e instrumentos para a sua avaliação, mas nenhum deles em espanhol. Oferecer experiências múltiplas e cumulativas em programas de formação de professores melhora a competência global do professorado, a reflexão crítica é essencial, e as parcerias com organizações comunitárias locais e internacionais são uma forma de contornar as limitações das experiências no estrangeiro.
Alfabetização midiática informacional aliada ao artivismo em busca de um fazer docente pautado na criticidade e na cultura da paz
Authors: Almeida Ângela Aparecida de
Published: June 2023

Este ensaio teórico em forma de artigo propõe uma reflexão sobre o potencial da alfabetização midiática informacional aliada a práticas de artivismo, em busca da formação de cidadãos com senso crítico, autônomo e reflexivo no exercício da liberdade, paz e cidadania. Por meio de pesquisa bibliográfica sobre alfabetização midiática informacional, artivismo, cultura da paz e educação, propõe-se a compilação de parâmetros teóricos e metodológicos que possam auxiliar a composição de práticas pedagógicas que possibilitem a constituição de uma identidade cidadã, participativa e não violenta, que consigam ser explorados em projetos e pesquisas envolvendo alfabetização midiática informacional e artivismo, tanto na educação formal como informal.
GROUPING OF POVERTY IN INDONESIA USING K-MEANS WITH SILHOUETTE COEFFICIENT
Authors: Erda Gustriza , Gunawan Chairani , Erda Zulya
Published: June 2023

Poverty is an enormous problem in numerous nations including Indonesia. Poverty can be measured using several indicators, including the unemployment rate, the percentage of poor people, expenditures per capita, and the poverty line. The purpose of this study is to categorize Indonesian provinces based on poverty indicators in 2021 using K-Means with the Silhouette Coefficient approach. Based on the silhouette coefficient approach, there are two clusters that are created. The first cluster is a high-poverty-rate regional group that includes the provinces of Aceh, Bengkulu, West Nusa Tenggara, East Nusa Tenggara, Central Sulawesi, Gorontalo, Maluku, West Papua, and Papua. On the other hand, the second cluster is an association of regions with a low poverty rate, and it includes 25 provinces. The greater number of provinces in the low poverty rate cluster implies that the poverty rate in Indonesia in 2021 is included in the low category
Changes in deoxyhemoglobin and admission duration in carbon monoxide poisoning patients: a retrospective study
Authors: Ji Jae Gu , Kim Yang Weon , Park Chul Ho , Yoon Yoo Sang , Jang Yundeok , Kang JI-Hun , Park Chang Min , Park Sang Hyeon
Published: June 2023

Purpose: The purpose of this study was to determine whether deoxyhemoglobin changes were associated with admission duration in carbon monoxide (CO)-poisoned patients.Methods: This retrospective study included 181 patients who were able to breathe by themselves after CO poisoning. Arterial blood gas analysis was performed to measure their deoxyhemoglobin levels. Their baseline characteristics and clinical outcomes during hospitalization in the emergency department (ED) were collected and compared. To assess changes in deoxyhemoglobin levels, blood samples were taken immediately after patients presented to the ED and then again after 6 hours. For statistical analysis, logistic regression was utilized to determine the effect of deoxyhemoglobin changes on admission duration.Results: The incidence rates of hypocapnia and hypoxemia at presentation after acute CO poisoning were 28.7% and 43.6%, respectively. Moreover, the magnitude of increasing deoxyhemoglobin levels in patients with hypoxemia (2.1 [1.7–3.1], p<0.001) and changes in deoxyhemoglobin levels appeared to have an impact on the length of hospitalization in the ED (odds ratio, 1.722; 95% confidence interval, 0.547–0.952; p<0.001).Conclusion: In patients with acute CO poisoning, deoxyhemoglobin levels appeared to increase in those with hypoxemia, which in turn was associated with prolonged hospitalization.
Development and Application of an MRM Method for Simultaneous Quantification of Sodium Channels Na v 1.1, Na v 1.2 and Na v 1.6 in Stable HEK293 cell lines, and Solubilized Membrane Proteins from Rodents and Human Brain Tissues.
Authors: Sojo Luis , Kwan Raibow , Das Prerna , Gerrebos Neelan , Li Jenny , Wang Xin Yin , DeBoer Gina , Emnacen-Pankhurst Vanessa , Lin Sophia , Feng Raymond , Goodchild Sam
Published: June 2023

Rationale Na 1.1, 1.2 and 1.6 are
transmembrane proteins acting as voltage gated sodium channels
implicated in various forms of epilepsy. There is a need for knowing
their actual concentration in target tissues during drug development.
Methods Unique peptides for Na 1.1, Na
1.2 and Na 1.6 were selected as
quantotropic peptides for each protein and used for their quantification
in plasma membranes from stably transfected HEK293 cells and rodent and
human brain samples using ultra‐high‐performance liquid
chromatography/electrospray ionization tandem mass spectrometry.
Results Na 1.1, 1.2 and 1.6 protein
expressions in three stably individually transfected HEK293 cell lines
were found to be 2.1±0.2, 6.4±1.2 and 4.0±0.6 fmole/µg membrane protein
respectively. Na 1.2 showed the highest expression,
with approximately 3 times higher (p<0.003) in rodents than in
human at 3.05±0.57, 3.35±0.56 in mouse and rat brains and 1.09±0.27
fmole/µg in human, respectively. Both Na 1.1 and 1.6
expressions were much lower than Na 1.2, with
approximately 40% less expression in human Na 1.1 when
compared with rodents Na 1.1 at 0.49±0.1 (mouse),
0.43±0.3 (rat), and 0.28±0.04 (human); while Na 1.6 was
approximately 60% less expression in human when compared to rodents at
0.27±0.09 (mouse), 0.26±0.06 (rat) and 0.11±0.02 (human) fmole/µg
membrane proteins. Conclusions MRM was used to quantify sodium
channels Na 1.1, 1.2 and 1.6 expressed in stably
transfected HEK293 cells and brain tissues from mouse, rat, and human.
We found significant differences in the expression of these channels in
mouse, rat, and human brains. Na expression ranking
among the three species was Na 1.2
>> Na 1.1> Na
1.6, with the human brain expressing much lower
concentrations overall in comparison to rodents.
Proteomics analysis of C2C12 myotubes treated with atrophy inducing cancer cell-derived factors
Authors: Marzan Akbar , Chitti Sai , Gummadi Sriram , Kang Taeyoung , Ang Ching-Seng , Mathivanan Suresh
Published: June 2023

Cancer-associated cachexia is a wasting syndrome that results in
dramatic loss of whole-body weight, predominantly due to loss of
skeletal muscle mass. It has been established that cachexia inducing
cancer cells secrete proteins and extracellular vesicles (EVs) that can
induce muscle atrophy. Though several studies examined these cancer-cell
derived factors, targeting some of these components have shown little or
no clinical benefit. To develop new therapies, understanding of the
dysregulated proteins and signalling pathways that regulate catabolic
gene expression during muscle wasting is essential. Here, we sought to
examine the effect of conditioned media (CM) that contain secreted
factors and EVs from cachexia inducing C26 colon cancer cells on C2C12
myotubes using mass spectrometry-based label-free quantitative
proteomics. We identified significant changes in the protein profile of
C2C12 cells upon exposure to C26-derived CM. Functional enrichment
analysis revealed enrichment of proteins associated with inflammation,
mitochondrial dysfunction, muscle catabolism, ROS production, and ER
stress in CM treated myotubes. Furthermore, strong downregulation in
muscle structural integrity and development and/or regenerative pathways
were observed. Together, these enriched proteins in atrophied muscle
could be utilized as potential muscle wasting markers and the
dysregulated biological processes could be employed for therapeutic
benefit in cancer-induced muscle wasting.
Percepción de los profesionales interventores de organismos colaboradores del Servicio Mejor Niñez sobre la vulneración de los derechos de niños, niñas y adolescentes en comuna centro-sur de Chile: una mirada desde el contexto de pandemia
Authors: Lobos Gabriela , Burgos Carlos , Ulloa Cynthia
Published: June 2023

El Servicio Mejor Niñez es un organismo público que tiene como objetivo garantizar la protección de derechos de niños, niñas y adolescentes al amparo de la ley N.º 21302. En los últimos años, se ha visto cuestionado tanto por la opinión pública como por organismos internacionales, por incumplimiento de las funciones para la cual se creó. En esta línea, el objetivo de esta investigación se centró en la percepción de los profesionales interventores sobre la vulneración de derechos sobre niños, niñas y adolescentes en la zona centro-sur de Chile. Estas personas son profesionales en Psicología y Trabajo Social que durante años han trabajado en programas de protección de vulneración de derechos, y han desempeñado un rol protector en cuanto a la protección de estos derechos. Para ello, se utilizó un método cualitativo basado en un enfoque fenomenológico, a partir de entrevistas que permitieron conocer los significados y percepciones sobre su ejercicio profesional. Los resultados destacan la visión opuesta y extrema de los profesionales sobre el proceso de intervención (satisfactoria y frustrante), así como la diversidad de modelos o enfoques utilizados en el proceso, lo que parece indicar que no existe una sistematización teórica en cuanto a la intervención que cada programa utiliza. Se estableció una reflexión importante sobre la ejecución de políticas en infancia y adolescencia que buscan promover el desarrollo integral en el marco postpandemia por COVID-19, considerando que muchas personas menores de edad se vieron nuevamente expuestas a vulneraciones de derechos durante el proceso de pandemia.
New family of Jacobi-Stirling numbers
Authors: Cakic Nenad , El-Desouky Beih , Gomaa Rabab
Published: June 2023

The Jacobi-Stirling numbers of the first and second kind were introduced in 2007 by Everitt et al. In this article we find new explicit formulas for Jacobi Stirling numbers. Furthermore, we derive and study new class of the Jacobi Stirling numbers so-called generalized Jacobi-Stirling numbers. Some special cases such as Legendre-Stirling numbers are given. Some interesting combinatorial identities are obtained.
Employing machine learning to assess the accuracy of near-infrared spectroscopy of spent dialysate fluid in monitoring the blood concentrations of uremic toxins
Authors: Trbojevic-Stankovic Jasna , Matovic Valentina , Jeftic Branislava , Nesic Dejan , Odovic Jadranka , Perovic-Blagojevic Iva , Topalovic Nikola , Matija Lidija
Published: June 2023

Hemodialysis (HD) removes nitrogenous waste products from patients? blood through a semipermeable membrane along a concentration gradient. Near-infrared spectroscopy (NIRS) is an underexplored method of monitoring the concentrations of several molecules that reflect the efficacy of the HD process in dialysate samples. In this study, we aimed to evaluate NIRS as a technique for the non-invasive detection of uremic solutes by assessing the correlations between the spectrum of the spent dialysate and the serum levels of urea, creatinine, and uric acid. Blood and dialysate samples were taken from 35 patients on maintenance HD. The absorption spectrum of each dialysate sample was measured three times in the wavelength range of 700-1700 nm, resulting in a dataset with 315 spectra. The artificial neural network (ANN) learning technique was used to assess the correlations between the recorded NIR-absorbance spectra of the spent dialysate and serum levels of selected uremic toxins. Very good correlations between the NIR-absorbance spectra of the spent dialysate fluid with serum urea (R=0.91) and uric acid (R=0.91) and an excellent correlation with serum creatinine (R=0.97) were obtained. These results support the application of NIRS as a non-invasive, safe, accurate, and repetitive technique for online monitoring of uremic toxins to assist clinicians in assessing HD efficiency and individualization of HD treatments.
Sabine Hossenfelder and the crisis of modern physics
Authors: Kandic Aleksandar
Published: June 2023

The book of one of the currently most famous female physicists, Sabine
Hossenfelder, Lost in Math: How Beauty Leads Physics Astray, is a reason for
discussing the crisis in which modern physics has fallen, as well as new
tendencies in physics as possible ways to overcome the situation. Part of
the responsibility for decades of stagnation in the development of physics
is borne by certain aspects of the heritage of ancient, specifically
Pythagorean-Platonic philosophy, which have found their place in modern
science. The critical insights presented by Hossenfelder are very well
founded. However, the author can be criticized for overlooking some ways of
thought in physics that represent a strong alternative to aesthetic
theoretical approaches, mostly inspired by ancient Greek natural philosophy.
For example, physicist Fritjof Capra?s book The Tao of Physics points to
numerous parallels between Eastern systems of thought and 20th century
physics.
Intraosseous Device Insertion for Adults and Pediatrics
Authors: Lau Jack , Thompson Judy
Published: June 2023

The position of the Association for Vascular Access is that intraosseous (IO) cannulation should be employed by qualified clinicians in all critical situations when vascular access is not established.

The insertion of an intraosseous device is a necessary tool. Central venous access device (CVAD) or peripheral intravenous (PIV) insertion should not be attempted under such conditions. In conscious patients, use a lidocaine protocol for infusions. Education and training must be established to have qualified operators and to decrease the barriers to appropriate use.

Reviewed by AVA Clinical Review Team Jan 2023

Adopted by the AVA Board of Directors
Langerhans Cell Histiocytosis Caused by Adalimumab for Crohn’s Disease: A Case Report
Authors: Mariko Kochi  , Higuchi Tetsuya
Published: June 2023

Abstract is missing (Short communication)
Psychosocial Factors Associated with Prolonged Length of Stay in Acquired Brain Injury Rehabilitation: A Retrospective Cohort Study
Authors: McDougall Alexandre , Mylabathula Swapna , Alavinia Mohammad , Kam Alice , Bayley Mark , Guo Meiqi , Tam Alan
Published: June 2023

Objective: In a climate of rising healthcare costs and increasing pressure to reduce inpatient length of stay, hospitals must balance their role as care providers with that as resource stewards. There is a need to understand what factors are associated with patients staying beyond rehabilitation length of stay targets. The aim of this study was to determine psychosocial patient factors that are identifiable on admission that influence length of stay targets in acquired brain injury rehabilitation.Methods: A retrospective case series of 167 inpatients with acquired brain injury was conducted at an urban, academic rehabilitation hospital. A total of 29 factors were used for data analysis. Logistic and multiple linear regression analysis was utilized to determine if any patient factors were associated with patients exceeding their length of stay targets.Results: Premorbid communal living status (e.g. group home) was associated with an odds ratio of 14.67 of exceeding length of stay target. Patients who did not drive prior to their admission had an odds ratio of 2.63 of exceeding their length of stay target. Conclusion: Premorbid communal living and premorbid non-driving status are predictors of patients with acquired brain injuries exceeding target rehabilitation length of stay. These findings may help acquired brain injury rehabilitation programmes plan for the needs of and advocate for patients.
LAY ABSTRACTIn the setting of rising healthcare costs, there is a need to understand which patient factors most affect why patients stay longer than anticipated in hospital. The aim of this study was to determine what non-medical factors affect rehabilitation length of stay in patients after brain injuries. A study of 167 patients with brain injuries was conducted at a rehabilitation hospital to determine if any patient factors were associated with patient hospital length of stay. The results show that patients who lived in communal environments, such as group homes, had 14.67 times the risk of exceeding their length of stay target compared to all other living arrangements. Patients who did not drive prior to their admission had 2.63 times the risk of exceeding their length of stay target compared to drivers. In our study, only patient living environments and driving status were predictors of meeting length of stay targets. These findings may help brain injury rehabilitation programmes plan for the needs of and advocate for their patients.
Clinical features and test indications of 11,087 patients undergoing cardiac magnetic resonance imaging during a decade in a tertiary referral center: A retrospective observational study
Authors: Jang Shin Yi , Kim Junghyun , Kim Yi Seul , Chang Young Ae , Jung Wooin , Kim Hwang Og , Yoo Kyungnam , Kim Eun Kyoung , Chang Sung-A , Park Sung-Ji , Park Seung Woo , Kim Duk-Kyung , Kim Sung Mok , Huh June , Song Jinyoung , Kang I-Seok , Cho Soo Jin , Oh Jae K. , Lee Sang-Chol , Choe Yeon Hyeon
Published: June 2023

Purpose: We evaluated the clinical characteristics of patients undergoing cardiac magnetic resonance (CMR) examinations over 10 years at a tertiary referral hospital.Methods: This retrospective study included 11,087 CMR examinations performed between November 2009 and September 2020. The number of adults aged ≥20 years was 10,648 (72.8% males). A total of 439 children or young adults aged < 20 years underwent CMR (66.5% males). Indications for CMR examinations were classified according to the Consensus Panel recommendations of the Society for Cardiovascular Magnetic Resonance (SCMR).Results: The mean age was 55.9±12.4 years for adults. Forty percent of patients were obese. Leading cardiovascular risk factors were hypertension, dyslipidemia, diabetes mellitus, and current smoking status in 28.2%, 19.1%, 13.8%, and 25.4% of patients, respectively. The proportion of stress CMR examinations performed was 57.2%. For children, the mean age was 12.6±5.3 years. Most children underwent a non-stress CMR test. In adults without congenital heart disease, indication numbers for SCMR classes were 5,682 for class I (49.4%), 772 for class II (6.7%), 313 for class III (0.3%), and 4,714 for investigational group (41.1%). In pediatric patients and adults with congenital heart disease, indication numbers for SCMR classes were 539 for class I (80.3%), 62 for class II (9.2%), and 70 for the investigational group (10.4%).Conclusion: CMR is most commonly performed in men in their 50s or 60s. CMR may be used as the first-line imaging technique (SCMR class I) in around a half of adult patients and in most pediatric patients.