bluuebunny/crossref_metadata_2025 huggingface dataset:
Discrete Dynamic Model of a Disease-Causing Organism Caused by 2D-Quantum Tsallis Entropy
Authors: Al-Saidi Nadia M. G. , Yahya Husam , Obaiys Suzan J.
Published: August 2022

Many aspects of the asymmetric organ system are controlled by the symmetry model (R&L) of the disease-causing organism pathway, but sensitive matters like somites and limb buds need to be shielded from its influence. Because symmetric and asymmetric structures develop from similar or nearby matters and utilize many of the same signaling pathways, attaining symmetry is made more difficult. On this note, we aim to generalize some important measurements in view of the 2D-quantum calculus (q-calculus, q-analogues or q-disease), including the dimensional of fractals and Tsallis entropy (2D-quantum Tsallis entropy (2D-QTE)). The process is based on producing a generalization of the maximum value of the Tsallis entropy in view of the quantum calculus. Then by considering the maximum 2D-QTE, we design a discrete system. As an application, by using the 2D-QTE, we depict a discrete dynamic system that is afflicted with a disease-causing organism (DCO). We look at the system’s positive and maximum solutions. Studies are done on equilibrium and stability. We will also develop a novel design for the fundamental reproductive ratio based on the 2D-QTE.
A Symmetric Extensible Protocol for Quantum Secret Sharing
Authors: Ampatzis Michael , Andronikos Theodore
Published: August 2022

This paper introduces the Symmetric Extensible Quantum Secret Sharing protocol, a novel quantum protocol for secret sharing. At its heart, it is an entanglement-based protocol that relies on the use of maximally entangled GHZ tuples, evenly distributed among the players, endowing the spymaster with the ability to securely share a secret message with the agents. Its security stems from the fact that it is highly improbable for a malicious eavesdropper or a rogue double agent to disrupt its successful execution. It is characterized by symmetry, since all agents are treated indiscriminately, utilizing identical quantum circuits. Furthermore, it can be seamlessly extended to an arbitrary number of agents. Finally, after the completion of the quantum part of the protocol, the spymaster will have to publicly transmit some information, in order to allow the agents to unlock the secret message. This part of the protocol can be considered as an additional advantage, due to the fact that it gives the spymaster the privilege of deciding if, or when, it is the right time for the agents to unlock the secret message, after the completion of the quantum part of the protocol.
Glycyrrhiza Polysaccharide Inhibits Pseudorabies Virus Infection by Interfering with Virus Attachment and Internalization
Authors: Huan Changchao , Xu Yao , Zhang Wei , Ni Bo , Gao Song
Published: August 2022

Pseudorabies virus (PRV) is one of the most important pathogens causing serious diseases and leads to huge economic losses in the global swine industry. With the continuous emergence of PRV variants and the increasing number of cases of human infection, there is an urgent need to develop antiviral drugs. In this study, we discover that Glycyrrhiza polysaccharide (GCP) has anti-PRV infection activity in vitro, and 600 μg/mL GCP can completely block viral infection. The addition of GCP simultaneously with or after PRV infection had a significant inhibitory effect on PRV. Addition of GCP at different times of the virus life cycle mainly led to the inhibition of the attachment and internalization of PRV but does not affect viral replication and release. Our findings suggest that GCP has potential as a drug against PRV infection.
Stromal Antigen 2 Deficiency Induces Interferon Responses and Restricts Porcine Deltacoronavirus Infection
Authors: Wu Yang , Zhang Hongling , Chen Jianfei , Shi Zhaorong , Li Mingwei , Zhao Ying , Shi Hongyan , Shi Da , Guo Longjun , Feng Li
Published: August 2022

Porcine deltacoronavirus (PDCoV) is a recently discovered enteropathogenic coronavirus and has caused significant economic impacts on the pork industry. Although studies have partly uncovered the molecular mechanism of PDCoV–host interaction, it requires further research. In this study, we explored the roles of Stromal Antigen 2 (STAG2) in PDCoV infection. We found that STAG2-deficient cells inhibited infection with vesicular stomatitis virus (VSV) and PDCoV, whereas restoration of STAG2 expression in STAG2-depleted (STAG2−/−) IPEC-J2 cells line restored PDCoV infection, suggesting that STAG2 is involved in the PDCoV replication. Furthermore, we found that STAG2 deficiency results in robust interferon (IFN) expression. Subsequently, we found that STAG2 deficiency results in the activation of JAK-STAT signaling and the expression of IFN stimulated gene (ISG), which establish an antiviral state. Taken together, the depletion of STAG2 activates the JAK-STAT signaling and induces the expression of ISG, thereby inhibiting PDCoV replication. Our study provides new insights and potential therapeutic targets for unraveling the mechanism of PDCoV replication.
Overview of the Current Literature on the Most Common Neurological Diseases in Dogs with a Particular Focus on Rehabilitation
Authors: Spinella Giuseppe , Bettella Piera , Riccio Barbara , Okonji Samuel
Published: August 2022

Intervertebral disc herniation, degenerative myelopathy, fibrocartilaginous embolism and polyradiculoneuritis often affect dogs; and physiotherapy may improve the patient’s quality of life and/or reduce recovery times. The aim of this review was to evaluate the current scientific outcomes on these four neurological diseases and on their physiotherapy approaches. From the analysis of the published articles, it emerged that intervertebral disc herniation can be treated, with different rates of success, through a conservative or a surgical approach followed by physiotherapy. The literature is generally oriented toward the efficacy of the rehabilitation approach in this specific canine disease, often proposing intensive post-surgery physiotherapy for the most severe conditions with the absence of deep pain perception. When degenerative myelopathy, fibrocartilaginous embolism or polyradiculoneuritis occur, the existing literature supports the use of a physiotherapeutic approach: allowing a delay in the onset and worsening of the clinical signs in degenerative myelopathy, physical improvement, and, sometimes, complete remission during fibrocartilaginous embolism or acute idiopathic polyradiculoneuritis. However, papers on rehabilitation in dogs affected by polyradiculoneuritis are currently limited to single clinical cases and further blinded, controlled, prospective studies are still advisable for all four neurological diseases.
Ocular Surface Squamous Neoplasia: A 12-Month Prospective Evaluation of Incidence in Waikato, New Zealand
Authors: Hossain Ruhella R , Oh Jee Ah , McLintock Cameron , Murphy Chris , McKelvie James
Published: August 2022

Ocular surface squamous neoplasia (OSSN) has a high incidence in the southern hemisphere. This prospective study evaluated the incidence of OSSN in the Waikato region of New Zealand. All patients presenting with pterygium or conjunctival lesions in the Waikato region in 2020 were included. All surgeons in the region were asked to send all conjunctival and corneal specimens excised for histopathologic examination. The primary outcome measure was the incidence of OSSN. Eighty-eight percent of all excised specimens were sent for histopathologic examination. Of the 185 excised lesions sent for histopathological assessment, 18 (10%) were reported as OSSN. Patients were on average 69.4 years of age (standard deviation, SD = 6.9), predominantly male (78%), and of New Zealand-European ethnicity (89%). The OSSN annual incidence was 3.67/100,000/year. Histology grades included conjunctival intraepithelial neoplasia (CIN)-I (25%), CIN-II (25%), CIN-III (12.5%), carcinoma in situ (25%), and invasive squamous cell carcinoma (SCC) (12.5%). One patient with invasive SCC required exenteration. This study identified a high incidence rate of OSSN and is the first prospective study to analyze OSSN epidemiology in New Zealand.
Joint Modelling of Flood Hydrograph Peak, Volume and Duration Using Copulas—Case Study of Sava and Drava River in Croatia, Europe
Authors: Lacko Martina , Potočki Kristina , Škreb Kristina Ana , Bezak Nejc
Published: August 2022

Morphodynamic changes in the riverbed may be accelerated by the climate change-induced effects, mostly through the increase of the frequency of extreme climatic events such as floods. This can lead to scouring of the riverbed around the bridge substructure and consequently reduces its overall stability. In order to better understand hydromorphological processes at the local scale, the influence of floods on bridge scour requires a detailed analysis of several interacting flood hydrograph characteristics. This paper presents a multivariate analysis of the annual maximum (AM) flood discharge data at four gauging stations on the Drava and Sava Rivers in Croatia (Europe). As part of the hydrograph analysis, multiple baseflow separation methods were tested. Flood volumes and durations were derived after extracting the baseflow from measured discharge data. Suitable marginal distribution functions were fitted to the peak discharge (Q), flood volume (V) and duration (D) data. Bivariate copula analyses were conducted for the next pairs: peak discharge and volume (Q–V), hydrograph volume and duration (V–D) and peak discharge and hydrograph duration (Q–D). The results of the bivariate copula analyses were used to derive joint return periods for different flood variable combinations, which may serve as a preliminary analysis for the pilot bridges of the R3PEAT project where the aim is to investigate the influences on the riverbed erosion around bridges with installed scour countermeasures. Hence, a design hydrograph was derived that could be used as input data in the hydraulic model for the investigation of the bridge scour dynamics within the project and a preliminary methodology is proposed to be applied. The results indicate that bivariate frequency analysis can be very sensitive to the selected baseflow separation methodology. Therefore, future studies should test multiple baseflow separation methods and visually inspect the performance.
Inland Navigation as an Opportunity to Increase the Cargo Capacity of the Tri-City Seaports
Authors: Kaizer Adam , Winiarska Magdalena , Formela Kamil , Neumann Tomasz
Published: August 2022

The aim of the article is to analyse the transport accessibility of the Tri-City seaports as well as to verify the necessity of starting the inland navigation. The proposal to develop inland navigation by creating new and developing existing waterways is supported by the idea of sustainable transport, which emphasizes how important it is to improve the efficiency of transport work and to minimize the harmful impact of transport on the environment. The purpose of the study is to determine the capability to increase the cargo capacity of the Port of Gdansk and the Port of Gdynia. The article presents the results of the operational analysis from the navigation and manoeuvring simulator Navi-Trainer Professional 5000, where scenarios that the barge from Tri-City seaports reaches the planned dry port in Zajączkowo Tczewskie have been made. This concept intends to verify the option of relieving truck traffic in the Tri-City area.
Impact of Fish Ponds on Stream Hydrology and Temperature Regime in the Context of Freshwater Pearl Mussel Conservation
Authors: Hoess Rebecca , Generali Konstantina A. , Kuhn Johannes , Geist Juergen
Published: August 2022

Conservation of endangered, cold-stenothermic species, such as the freshwater pearl mussel (FPM) and its salmonid host fish, are particularly challenging in headwater streams as their last refuge areas. Understanding the impact of anthropogenic catchment features such as fish ponds on the hydrology and the temperature regime of such streams is, therefore, important. In this study, runoff in a FPM catchment with more than 150 small ponds was simulated using SWAT and compared to a scenario without ponds. Additionally, water temperature was monitored hourly along three steams over 2.5 years, at sites upstream and downstream of the inflow of pond outlet channels. Temperature metrics were related to land use within a 180 m corridor along the streams. Peak flows were reduced by 1.5% with ponds, while low flows were increased by 4.5%. In summer, temperature in pond effluents was higher than in the receiving stream, depending on the proximity of the inflow points. Discharge from close-by ponds increased summer stream temperature directly downstream of the inflow by up to 5.5 °C. These increased temperatures were partly compensated by groundwater contribution in forested areas. In contrast, stream temperature significantly further increased along stretches flowing through open land, persisting independently of pond inflows. We suggest incorporating this knowledge on pond- and land use-dependent effects on stream temperature regimes into the conservation management of FPM and other cold-stenothermic species, as well as into climate change mitigation strategies targeting an increased resilience against temperature extremes.
Synergistic Effect of Ferrate with Various Water Processing Techniques—A Review
Authors: Zhang Shaoqing , Jiang Jia-Qian
Published: August 2022

The use of ferrate has been demonstrated as a highly efficient technique for the removal of pollutants in water and wastewater treatment. While most of the published work about ferrate investigated the treatment performance by ferrate alone, new applications of ferrate expand to the synergistic application of ferrate with other techniques such as membrane separation, sulphur-based chemical use, UV radiation, ozonation, acidification, and other chemical additives. This paper aims to review and explore the treatment performance and reaction mechanisms associated with synergistic applications of ferrate. The main objective of this study is to conduct case studies on the synergistic application of ferrate with other water processes. It was found that the efficiency of water treatment increased significantly by the synergistic application of ferrate, and this is attributed to the alleviation of membrane fouling, the activating the formation of more radical oxidative species, enhanced coagulation, and the potential improvement of micropollutants’ biodegradability. Therefore, the stated ferrate technology holds high potential for improving the efficiency of water treatment and other environmental remediation processes. Further studies are required to explore a more feasible combination of ferrate with other techniques and expand the understanding of the working mechanisms of the known synergistic applications of ferrate.
Identification of Suitable Locations in a Small Water Supply Network for the Placement of Water Quality Sensors Based on Different Criteria under Demand-Driven Conditions
Authors: Tsitsifli Stavroula , Kanakoudis Vasilis
Published: August 2022

Drinking water quality monitoring in real time is of utmost importance to ensure public health. Although water utilities, following the related legislative framework, monitor drinking water quality through samplings, the likelihood of detecting contaminants in consumers’ taps is low, depending on the scale of the monitoring programme. Additionally, even if the monitoring frequency is high, there is a time delay since sampling and analysis processes take some time. The selection of suitable locations for the installation of online water quality sensors is a hard task for a water utility due to the complexity of the water distribution system, the limitations of certain network junctions which are not easily accessible, and the computational burden involved. This topic has been extensively studied in recent years and sophisticated methods have been developed using optimization techniques. However, small water utilities do not have the means to implement such tools. This paper applies a methodology to identify the suitable junctions for the installation of online water quality sensors based on different objectives and under demand-driven conditions. This paper utilizes the hydraulic simulation model of a standard network to set up the water quality simulation model. A thorough analysis of various contamination scenarios takes place with different injection nodes and at different starting injection times for 24 h. The latter relates to the contaminant’s spread due to varying water demand. After a thorough analysis of 816 scenarios, a prioritized list of the most suitable nodes for the installation of the sensors is available for each optimization objective. Comparing the prioritized list of nodes achieved from each single or multi-objective function, the detection probability is almost the same. The analysis revealed that, due to varying water demand conditions, the ranking of the proposed nodes suitable for the installation of water quality monitoring sensors differs. Thus, varying hourly water demand should be part of analyses seeking to get reliable results.
A Study of the Agricultural Water Supply at the Hoengseong Dam Based on the Hydrological Condition of the Basin
Authors: Kim Deokhwan
Published: August 2022

Since South Korea relies on dams and agricultural reservoirs for approximately 45% of its annual agricultural water usage, the supply control of agricultural water based on its usage amount is essential for effective water resources management. The objective of the study, therefore, is to suggest an alternative to the agricultural water supply from the Hoengseong Dam using the threshold curve of usage record that was suggested in the previous study. The characteristics of agricultural water usage and Usage Rate compared to the Permission amount (URP) threshold curve of the Seom River basin, which is defined as the thresholds of the maximum usage rate of agricultural water in each hydrological condition, were derived and analyzed using the historical record of runoff and agricultural water usage. The agricultural water supply of the Hoengseong Dam was simulated from 2006 to 2021 according to the URP threshold curve. As a result, it was found that the agricultural water usage rate of the Seom River Basin can be up to 106.5% even with the average hydrological condition compared to normal years. It was also shown that about 1.7 million m3 of agricultural water could be stored by applying the URP threshold curve to the agricultural water supply of the Hoengseong Dam annually.
The PlaceMarker Survey: A Place-Based Tool for Supporting the Monitoring and Appraisal of River-Related Projects and Natural Capital Assessments
Authors: Wharton Geraldene , Gurnell Angela M. , Ross Mark , Pereira-Gurnell Dave
Published: August 2022

The PlaceMarker Survey is an operational tool to support the delivery of the core aims of England’s Environment Agency (EA) in helping to increase resilience to climate change, manage flood risk, and create a better place for people and wildlife. It was developed in response to a recognised need by the EA’s National Environmental Assessment and Sustainability (NEAS) team for a broad-based survey undertaken in the field to get to know the site and prior to more specialist surveys. The key aim of the survey is to capture in a systematic and consistent way the character and condition of a place where river-related projects such as flood risk management and river restoration schemes are proposed to inform discussions around the design and planning of a project and provide the baseline for future place-based monitoring. The tool comprises: a Study Area Survey and one or more River Surveys, which provide measurements to generate metrics and information to support assessments of Habitat and Biodiversity, Landscape, Amenity, and Heritage. Data are stored, analysed, retrieved, shared, and displayed through a web-based information system. It is intended that a PlaceMarker Survey will be conducted on at least three occasions in the lifetime of a project or asset: pre-inception of a project to understand the broad environmental baseline and assist in the design of a scheme; immediately post-project to confirm the “as-built condition”; and post-recovery from the works to monitor the environmental response to interventions at the site. Tracking the assessments over time informs evaluations of environmental enhancements and supports decision-making around adaptive management.
Desarrollo de competencias informacionales en la educación superior.
Authors: Cedeño Palacios Gema María , Morales Intriago Juan Carlos , Arteaga Pita Iván Gasendy
Published: August 2022

La alfabetización informacional se impulsa como un componente esencial de conocimientos para la formación en la educación superior, por tanto, desde los primeros niveles se deben alcanzar en cierta medida competencias informacionales para el desempeño óptimo de sus actividades de formación. El objetivo de este trabajo es identificar cualidades asociadas con el desarrollo de competencias informacionales y su vínculo con los programas de formación de usuarios. Para ello se realizó una investigación documentada de tipo no experimental, mediante una revisión de la literatura organizada en: preguntas de investigación; criterios de inclusión y exclusión; estrategias de búsqueda y términos base; construcción y selección de la cadena de búsqueda; proceso de selección y depuración de referencias; selección de estudios primarios; y extracción de datos, centrada en la caracterización de las competencias informacionales, sus formas de medición y su relación con los resultados de programas de formación. En consecuencia, las contribuciones provienen de las bases de datos Scopus, ERIC, WOS y Springer, de los que se obtiene un conjunto de elementos agrupados en: búsqueda de información, la evaluación de la información, preparación de la información en procesos específicos, aspectos éticos y formas de compartir la información. En conclusión, las cualidades más importantes son: la claridad de las necesidades de información, la búsqueda y selección adecuada de fuentes de información, las estrategias aplicadas para la búsqueda de información, el análisis y pensamiento crítico centrado en la evaluación de la información, con el objetivo de comprender, interpretar y sintetizar la información de la literatura preexistente.
ETIOLOGIA DO BRUXISMO INFANTIL
Authors: Oliveira Hanna Leila Maués , Silva da Silva Joseph Lwy , Carvalho Pereira Sabrina Nunes
Published: August 2022

Introdução: o bruxismo é um hábito parafuncional, relacionado com vários distúrbios dentários, um movimento involuntário, podendo ser em vigília ou durante o sono, sendo em crianças sua ocorrência mais frequente. O bruxismo afeta a qualidade de vida das crianças, por muitas vezes causando danos ao sono, dores de cabeça e nos músculos da face. Objetivo: esta revisão interativa tem por objetivo relatar sobre a etiologia do bruxismo infantil. Método: foram consultados sites de pesquisa avançada, tais como, Scopus of sciense, Bvs, Scielo, Lilacs, Pubmed e Portal de periódicos da capes. Resultado: o bruxismo é considerado de etiologia multifatorial, envolvendo fatores sistêmicos, psicológicos, hereditários e distúrbios de sono. O tratamento deve ser associado a equipe multidisciplinar, envolvendo pediatras, odontopediatras, psicólogos, otorrinolaringologistas e médicos gastroenterologista. Conclusão: é de extrema importância o diagnóstico precoce, para prevenir danos ao sistema estomatognático, e proporcionar conforto e bem estar do paciente.
METHODOLOGICAL FEATURES OF DETERMINATION THE SPECIFIC SURFACE ENERGY OF MINERAL QUARTZ-CONTAINING POWDERS
Authors: Frolova M.
Published: August 2022

Methods for sample preparation of prototypes for the subsequent determination of the specific surface energy by the Owens, Wendt, Rabel and Kaelble (OWRK) method are worked out on the example of highly dispersed powders of quartz sand, characterized by a SiO2 content of 98.3%. For this purpose, dry grinding in a planetary ball mill disperses the raw material, the mechanical activation time is varied in the range of 15÷45 min. Five fractions of highly dispersed powders are obtained. They are characterized by the specific surface area. This parameter is changed in the following range: 1200÷3000 kg/m2. Prototypes for subsequent research by the OWRK method are made by pressing with a pressing force of 2 to 16 tons. As a criterion for optimizing sample preparation conditions, the coefficient of determination of the functional dependence of the cosine of the wetting angle of the surface of test samples with working fluids (decane, glycerin, water) on the dispersion component of their surface tension is proposed. It has been established that for the quartz sand used, the maximum value of the coefficient of determination (0.94) is noted at a pressing force of fine fractions equal to two tons. An increase in the specific surface area of powder materials over 2370 kg/m2, obtained by mechanical dispersion and an increase in pressing force up to 12÷16 tons, leads to additional errors in determining the surface tension of compacted prototypes by the OWRK method.
UNIVERSAL ANALYTICAL DEPENDENCE OF DEFORMATION-STRENGTH PROPERTIES OF REINFORCING STEELS UNDER FORCE TENSION
Authors: Donchenko Oleg , Suleymanova L. , Kryuchkov A. , Logachev K.
Published: August 2022

The article deals with topical issues of the normative methodology for calculating bending and eccentrically compressed reinforced concrete elements along normal sections. They are based on the joint use of a nonlinear deformation model, the hypothesis of flat sections, physically and geometrically linear diagrams of the mechanical state of reinforcing steels of various strengths under force tension. Attention is drawn to the significant inaccuracies of calculations when using the approximate rectilinear steel deformation modulus of constant value E = 2 105 MPa up to the steel's ultimate strength. The high degree of complexity of manual calculation is confirmed when using the actual values of the physically nonlinear steel deformation modulus, approximated by analytical dependences of high degrees. A new author's approach is presented for solving such problems by approximating the real nonlinear strain modulus to the secant strain modulus E's with simple equations for high-strength “hard” and “soft” (not high and medium strength) steels, which allows to manually calculate such problems with greater accuracy.
Creative figure of V. I. Sokalskyi as Kharkіv genius loci in Z. B. Yuferova’s res omnis aetatis
Authors: Olena Roshchenko
Published: August 2022

Statement of the problem. The article aims to recreate the features of two historical portraits: the composer and musical critic V. Sokalskyi (1863–1919), whose name belongs to the history of the “pre-conservatory” musical Kharkiv, and the researcher of his work Z. Yuferova (1931–1999), whose monograph dedicated to V. Sokalskyi has become a matter of life (“res omnis aetatis”). The innovative element of the study is the development and introduction into musicology the dialogical research method, which allows identifying the researcher’s scientific method by analyzing the composer’s creative portrait, which she recreated in her work. The methodological basis of the study is supplemented by historical-cultural and historical-contextual analyses based on the material of Z. B. Yuferova’s monograph (2014, published posthumously) dedicated to V. I. Sokalskyi. Conclusions and results of the study. Dialogic research method made it possible to create a double historical portrait, which, on the one hand, reveals the features of the composer’s creative thinking, on the other hand, exposes the researcher’s professional qualities. According to Z. Yuferova, V. Sokalskyi is a pioneer of many genres in Ukrainian music; a person with high human virtues, chivalrous courage of his critical judgments, sincere service to the cultural flourishing of his native city. In turn, the personality of the researcher is characterized by her respect for historical facts, motivated problem analysis, systemic thinking, careful reproduction of the cultural background, reasonable conclusions, and encyclopedic knowledge. High professionalism embodied on the pages of Z. Yuferova’s substantial monograph gives every reason to agree with her assessments, and along with the recognition of the composer and music critic Sokalskyi as a “genius” of artistic Kharkiv at the turn of the 20th–21st centuries, to consider him a much more prominent all-Ukrainian figure. The introduction of V. Sokalskyi’s works into educational and concert programs should become an important prospect for the further revision of the history and renewal of the performance repertoire of the national musical culture.
Treatment of Arrhythmias in the Context of the COVID-19 Pandemic
Authors: Якубова Л.В. , Снежицкий В.А.
Published: August 2022

В статье приведен обзор литературных данных по регистрации и течению различных аритмий у пациентов с COVID-19, частота развития которых была от 8 до 17% и достигала 44–60% в отделениях интенсивной терапии. Описаны основные патофизиологические механизмы, которые совпадают с клиническим течением COVID-19 и могут предрасполагать к развитию аритмий. На сегодняшний день лечение нарушений ритма и проводимости сердца у пациентов с COVID-19 должно проводиться в соответствии с текущими национальными и международными рекомендациями. В статье приведены шкала стратификации риска лекарственно-индуцированного удлинения корригированного интервала QT, а также список наиболее часто используемых препаратов, удлиняющих QTc. Сделан акцент на необходимости выявить и скорректировать модифицируемые факторы риска, к которым прежде всего относятся: гипокальциемия, гипокалиемия, гипомагниемия, одновременное применение препаратов, удлиняющих интервал QTc, и брадикардия. В статье подчеркивается важность рационального выбора лекарственных средств клиницистами и оценки их взаимодействия, а также важность мониторинга ЭКГ у пациентов с риском развития аритмии.

The article provides a review of the literature data on the registration and course of various arrhythmias in patients with COVID-19, the incidence of which was from 8 to 17% and reached 44–60% in intensive care units. The main pathophysiological mechanisms are described, which coincide with the clinical course of COVID-19 and may predispose to the development of arrhythmias. To date, the treatment of cardiac arrhythmias and conduction disorders in patients with COVID-19 should be carried out in accordance with current national and international guidelines. The article provides a risk stratification scale for drug-induced prolongation of the corrected QT interval, as well as a list of the most commonly used drugs that prolong QTc. The emphasis is on the need to identify and correct modifiable risk factors, which primarily include: hypocalcemia, hypokalemia, hypomagnesemia, simultaneous use of drugs that prolong the QTc interval, and bradycardia. The article emphasizes the importance of rational choice of drugs by clinicians and evaluation of their interactions, as well as the importance of ECG monitoring in patients at risk of developing arrhythmias.
Spontaneous Muscle Hematoma in Patient with COVID-19: Case Report
Authors: Каленчиц Т.И. , Кабак С.Л. , Примак С.В. , Цедрик Л.Г.
Published: August 2022

В статье описан клинический случай формирования обширной внутримышечной гематомы боковой стенки живота и гематомы в четырехглавой мышце бедра у пациентки с COVID-19-пневмонией средней тяжести на фоне антикоагулянтной терапии гепарином. На 6-е сутки после поступления на стационарное лечение по данным УЗИ гематома в области боковой стенки живота достигла объема 1200 мм, а в верхней трети правого бедра – 260 мл. Образование гематом сопровождалось подкожными кровоизлияниями, изменениями параметров гемостазиограммы и падением артериального давления. Концентрация гемоглобина в сыворотке крови снизилась до 44 г/л. Пациентка была переведена в анестезиолого-реанимационное отделение (АРО), где ей под местной анестезией и под контролем УЗИ на 3 см выше правой паховой связки была произведена пункция гематомы и установка ПВХ дренажной трубки. Из трубки под давлением получено около 300 мл серозно-сукровичной жидкости (фибринолизированной крови) без сгустков. В полость гематомы вводились гемостатические препараты, восстанавливался объем циркулирующей крови, подкожное введение гепарина было отменено.

The article describes a COVID-19 patient with large hematomas of the abdominal wall and quadriceps femoris as a complication of anticoagulation therapy with heparin. According to abdominal ultrasound on the 6dth day after admission, the volume of the abdominal wall hematoma was 1200 ml, and the volume of the hematoma in the upper third of the right thigh was 260 ml. Sings of intramuscular hematomas included subcutaneous hemorrhages, changes in hemostasiogram parameters, a decrease in the level of hemoglobin in the blood serum, and a drop in blood pressure. The hemoglobin level in the blood serum decreased to 44 g/l. The patient was transferred to the anesthesiology and intensive care unit (ARO), where, under ultrasound-guided regional anesthesia 3 cm above the right inguinal ligament, a hematoma puncture was performed and a PVC drainage tube was placed. About 300 ml of serosanguineous fluid (fibrinolyzed blood) without clots was obtained from the tube under pressure. Hemostatic agents were put into the hematoma cavity, the volume of circulating blood was restored, subcutaneous administration of heparin was stopped.
Privacy Risks and Security Threat Strategy to Optimize the Vulnerability in Health Information System (HIS)
Authors: Amanul Islam Mohammad
Published: August 2022

Health information systems (HIS) generally access, process, or maintain large volumes of sensitive data corresponding to the patient, health service provider (HSP), clinicians, and other stakeholders. Hence, ensuring health data security is a primary concern to improve patient outcomes, inform research, and influence policymaking. Many countries across the world practice data protection and privacy preservation laws against numerous threats related to health data and its communication between the computer networks. Hence, resolving the health information security flaws by designing a potential threat model is always given significant importance. The main objective of this study is to emphasize the concerns related to privacy risks and security threats with the use of HIS.
Analysis of Frequency and Polarization Scaling on Rain Attenuated Signal of a KU-Band Link in Jos, Nigeria.
Authors: Jangfa Timothy Zhimwang , Samuel Shaka Oghenemega , Lagbegha-ebi Mercy Frank , Aminu Ibrahim , Yunisa Yahaya
Published: August 2022

This paper presents the analysis of frequency and polarization scaling on rain attenuated signal of a KU-Band link. The study was carried out in Jos, Plateau state, Nigeria (9.89650 N, 8.85830 E; 1192 meters) with Maximum, Average and Minimum Temperatures of 29.80C, 22.80C and 170C respectively. Data were obtained for the months of May, June, July, August, September and October 2020.Davis Vantage Vue weather station was used to measured and record one-minute rain-rates from a minimum of 0.8 mm/h up to a value of 460 mm/h, with an accuracy of 0.2 mm/h. The precipitation data, with date and time is captured on the micro-chip of the wireless electronic data logger, which, when calibrated, logs on data every minute. The down converted Ku-band signal was fed into the digital satellite meter and a spectrum analyzer for signal level analysis, logging and recording samples of viewed spectrum over finite periods of time on a computer system. Both satellite signal and precipitation measurements were done concurrently. Data were analyzed using Microsoft excel and results were obtained based on ITU-R model. Results obtained revealed that rain attenuated signal for vertical and horizontal polarization varies for different rain rate and months under reviewed. For the month of May 2020, rain attenuated signal is more severe from rain rate of 100mm/hr with the highest rain attenuation of 25.57dB, 30.37dB, and 39.84dB at frequencies of 12GHz, 15GHz and 18GHz respectively while the rain attenuated signal for vertical polarization is more severe from 80mm/hr with highest recorded rain attenuation of 27.96dB, 40.33dB and 45.71dB at frequencies of 12GHz, 15GHz and 18GHz respectively. For the month of July 2020, the results shows that rain attenuated signal for vertical polarization is more severe from rain rate of 80mm/hr with the highest rain attenuation of 60.57dB, 73.37dB, and 100.84dB for frequencies of 12GHz, 15GHz, and 18GHz respectively. At Horizontal polarization, signal losses are more severe from 60mm/hr. The results further proves that frequency and polarization scaling of rain attenuated signalare major factors to consider when designing a microwave link budget especially in the study area that experiences high amount of rainfall annually.
استخدام النمذجة الرياضية AHP ونظم المعلومات الجغرافية GISفي تقييم ملاءمة الأراضي لزراعة القمح في وسط سوريا
Authors: Khallouf Alaa , Mohammed Safwan A. , Almesber Waseem
Published: August 2022

مع التغيرات المتلاحقة في النمو السكاني وازدياد الطلب على الغذاء في الدول النامية، أصبحت إدارة الموارد الطبيعة  والمحدودة، بطريقة منهجية وعلمية ومستدامة أمراً ضرورياً. ويهدف هذا البحث إلى تقديم نهج متكامل لعملية تحليل ملاءمة الأراضي الزراعية لنمو محصول القمح في منطقة جورين من سهل الغاب في سوريا باستخدام نموذج التسلسل الهرمي التحليلي (AHP) ضمن بيئة نظم المعلومات الجغرافية (GIS). و لتقييم درجة الملاءمة، تم تحديد ثمانية معايير وهي: نسيج التربة، الميل، عمق التربة، محتوى المادة العضوية، محتوى كربونات الكالسيوم (CaCO3)، سعة التبادل الكاتيوني (CEC)، درجة الحموضةPH) )، والتوصيل الكهربائي (EC)، ثم تم إعداد الخرائط اللازمة وفي مرحلة لاحقة تم إجراء المقارنات الثنائية بين المعايير المدروسة. وأظهرت النتائج أن 25.6٪ ​​من المساحة المدروسة مناسبة جداً وذات ملاءمة عاليةS1، بينما شكلت نسبة المناطق المتوسطة الملاءمة S2 56.33٪، وتوزعت 16.45٪ من أراضي منطقة الدراسة بملاءمة هامشيةS3، وكانت 1.61٪ هي أراضي غير صالحة لزراعة القمح N1.
Expanding the Shelf-Life of Ready to use Shredded Icebergs by Using Oxidation - Reduction Potential controlled Release of Various Chlorine Concentrations in Washing Water
Authors: Abdullah Mai Adnan , Alawamleh Heba Saed , Al- Nasraween Moath S.
Published: August 2022

Ready to use (RTU) shredded iceberg lettuce is a perishable product with a short shelf-life. Expanding the shelf life to seven days of this product as an economic need for the producers is the aim of this research. Fresh samples were harvested from the field and prepared according to the standard protocol of minimal processing fresh produce (receiving, removing dribs and pre-washing, washing, de-watering, packaging, and storing). Several concentrations of sodium hypochlorite were precisely optimized by oxidative/ reductive Potential (OPR) automated dozing pump under controlled neutral pH and cold temperature during washing regimen. Samples were vacuumed packed and kept tightly sealed at 4 °C for further analysis. Aerobic plate count and coliform as well as sensory evaluation were performed. Results showed that at a chlorine dose level less than 700 mV ORP, the shredded lettuce deteriorated due to elevated microbial load as well as from a sensory point of view. The level of 700 and 800 mV ORP extended shelf life for 7 days. Washing with chlorine levels higher than 800 mV showed alteration in sensory attributes although the microbial load was under control.

Results of this study show that the automated ORP chlorine dozing “in form of sodium hypochlorite” at 700 mV (50 ppm) and 800 mV (100 ppm) within controlled pH and temperature, followed by storing the vacuumed well-sealed packs at 4 °C, were the best measures taken to increase the shelf life of the shredded iceberg lettuce from 5 to 7 days. Furthermore, there was no significant difference between the uses of an ORP reading of 700 mV vs. 800 mV of chlorination. However, it is preferable to use the 700 mV ORP reading because it will release less chlorine in the washing water, hence, it will be healthier and more economical.
Response Postharvest Quality of Diyala Orange to Two Rootstocks and Some Plant Extracts
Authors: Aljabarya Ali Muhi Aldeen Omar , Ahmadb Zhala Muhammad , Fatihb Avan Assi
Published: August 2022

This study was performed on Diyala orange fruits to investigate the role of sour orange and Lemon rootstocks and the dipping in (0, 2, 4, and 6) % from each aqueous extract of clove flower buds, thyme leaves, and pomegranate peel for four minutes on extending the storability and maintain postharvest quality of Diyala orange fruits. A factorial experiment was used within Randomized Complete Design with three replicates.

 The fruits were placed in polyethylene bags, subsequently stored at 6±1 ºC and 85-95% relative humidity for two months. The results indicated that fruits were grown on sour orange rootstock significantly maintained the highest values in most of the chemical properties were studied, likewise reducing the weight loss and physiological disorders than fruits were grown on lemon rootstock. Concerning the plant extracts, fruits immersed in 2% clove extract had the maximum values of total soluble solids (TSS), vitamin C, and total phenol than control. Furthermore, fruits immersed in 6% thyme extract had the highest values of TSS, total sugar, vitamin C, and total phenol, whereas, minimized physiological disorders than control. Likewise, fruits immersed in 2% Pomegranate peel extract had the highest values of TSS and vitamin C but had lower physiological disorders than control.
Use of Enzymatic Preparations to Improve the Productivity and Quality of Olive Oil
Authors: Al-Rousan Walid M. , Al-Marazeeq Khaled M. , Abdullah Mai A. , Al- Khalaileh Nazieh I. , Angor Malak M. , Ajo Radwan Y.
Published: August 2022

Improving the quantity and quality of olive oil extraction is considered crucial for producers not only in Jordan but also worldwide. The present study aimed to enhance olive oil yield from olive fruits without compromising its quality by applying an enzymatic treatment technique during the malaxation stage of the oil extraction process.

The enzymes that were used in this study were cellulase, pectinase, and a mixture of both enzymes at a ratio of (1:1). Each of the enzymes and there mixture was added at concentrations of 0.02 %, 0.04 % 0.06 %, 0.08 %, 0.10 %, and 0.12 % (w/w). Two Jordanian olive cultivars, Nabali Baladi (NB) and Nabali Muhassan (NM), in their immature state, were selected for the enzymatic treatment. The olive oil yield increased significantly (P < 0.05) after the enzymatic treatment. The increments in yield were 4.38 % (at an enzymatic concentration of 0.08 %), 3.29 % (at 0.1 %), and 5.25% (at 0.12 %) for NB treated with cellulase, pectinase, and 1:1 cellulase/pectinase, respectively. The increments in oil yield were 4.08 % (at 0.1%), 3.09 % (at 0.12%), and 4.5 (at 0.08%) for NM treated with cellulase, pectinase, and 1:1 cellulase/pectinase, respectively. The percent increments were significantly (P < 0.05) higher for NB than for NM. The quality parameters in terms of acidity, peroxide values, and UV-extinction coefficients at 232 and 270 nm were not significantly affected in any of the treatment groups when compared to those of control samples. The content of phenolic compounds, α-tocopherols, chlorophylls, and carotene was significantly higher (P < 0.05) in both oils in all enzymatic treatments than in the control, resulting in increased oxidative stability, as revealed by Rancimat analyses.
What to Know about Food Flavor? A Review
Authors: Al Saqqa Ghada S. R.
Published: August 2022

The primary function of flavors is to add taste or aroma to foods, as they have no nutritional properties. According to Flavor and Extract Manufacturers Association (FEMA), flavors have a place in the food supply to meet consumer demand for a variety of safe and tasty products. This review provides an overview of the three flavor groups; natural flavors, nature-identical flavors, and artificial flavors, where they are added to replace the flavor lost through processing and to develop new products, while flavor enhancers are compounds with no intrinsic aroma or taste of their own, but when are added in low concentrations to appropriate foods,  they improve the palatability of the food distinctly, a popular example is monosodium glutamate. The food industry is constantly striving to improve the quality and taste of modern food products through creating new flavors and improving existing ones. The flavors of commercially produced food products are usually created by florists who work for flavor companies. Among these commercial flavors are those that are often added to elderly food to offset the losses in their sense of smell and taste. Encapsulation can be used to treat flavors and protect them from evaporation, reaction, or disappearance from food. Flavors manufacturers need to know which ingredients are allowed in the community that includes restrictions and specific requirements for use in food applications.
Morphological Variability Assessment of Worldwide Germplasm of Pharmaceutically Important Plant Nigella Sativa L.
Authors: Aftab Arusa , Yousaf Zubaida , Rasheed Madiha , Younas Afifa , Qamar Nadia Riaz , Yasin Hamna , Shamsher Hafiza Bushra
Published: August 2022

N. sativa is an important industrial crop globally but neglected crop in Pakistan, hence imported. It has been used for revitalizing body system in almost all ancient civilizations. In the present investigation worldwide accessions of N. sativa were cultivated for three years to select the most diverse accessions for cultivation and future breeding purpose in Pakistan. More diverse and acclimatized accessions with enhanced morphological traits were observed. Seed length, seed width, plant height, number of flowers and number of follicles showed maximum considerable variation in three years. Morphological variations observed and collected for all three years were not consistent among all accessions, due to some environmental fluctuations while some of the accessions like ACC 20662, ACC W626529, ACC 20878, ACC 21545, ACC 21428and ACC 20990 showed consistency at some extent among results of different morphological markers (number of flowers, number of stamens, number of follicles, follicle length, follicle width and seed per follicle). 50% accessions germinated in 26-35 days consecutively three years and showed optimum growth. The maximum height was noticed as 108cm in two accessions ACC 20878 and ACC 20780. The maximum frequency of flower initiation days was noted 101-110 days. The maximum frequency distribution for number of branches was noted in frequency class 11-15 during all three years. The maximum frequency of flower initiation days was noted 101-110 days for 2015-16 and 2017-18. The data recorded in 2017-18 depicted the maximum number of flowers as 15 (ACC 20780 and ACC 20878). The rate of follicle production per plant was 10 among accessions (ACC W626529, ACC 20545 and ACC 21295). The largest frequency class for stamens number was 21-25 stamens, whereas the plants with frequency class 31-35 stamens were least frequent. The flower color varied in the recombinant plants (RC) as Purple White whereas in the parents it was White (Jordan) and Bluish white (Ukraine).  In general the accessions belonging to Gujranwala, Jordan, Lahore, Haripur, Attock and Sargodha were found morphologically more significant and diverse.