bluuebunny/crossref_metadata_2025 huggingface dataset:
AI Testing for Intelligent Chatbots – a Case Study
Authors: Gao Jerry , Agarwal Radhika , Garsole Prerna
Published: February 2025

Inspired by principles of the decision tree test method in software engineering, this paper provides a discussion on intelligent AI test modeling chat systems, including basic concepts, quality validation, test generation and augmentation, testing scopes, approaches, and needs. The novelty of the paper lies in an intelligent AI test modeling chatbot system that is built and implemented based on an innovative 3-dimensional AI test model for AI-powered functions in intelligent mobile apps to support model-based AI function testing, test data generation, and adequate test coverage result analysis.
A Mixed Reality Digital Twin Application of a Diaphragm Actuator
Authors: de Juan Andrew , O' Mahony Kevin , Buggy Robert , Wolfe Raymond , Geaney Eoin
Published: February 2025

Digital Twin (DT) technologies are becoming ubiquitous within industrial and manufacturing environments, particularly, in the biopharmaceutical production sector. This project explores the integration of Mixed Reality (MR) technology with Digital Twin (DT) systems in industrial environments, focusing on biopharmaceutical production. In collaboration with an industry partner, a small-scale Mixed Reality Digital Twin (MRDT) application was developed for a diaphragm actuator, utilizing MQTT and HTTP protocols to transmit real-time sensor data to a HoloLens 2 headset. The application demonstrated the capability to query, visualize, and publish real-time data associated with the actuator’s properties. By providing immersive, holographic representations of equipment conditions, this approach shows potential for optimizing preventative maintenance methods. The project highlights the possible value of integrating MR technology with DT systems in industrial settings, particularly in supporting service technicians for more effective maintenance and replacement of process equipment.
Insomnia and Life Satisfaction in Esports Players: Examining Mindfulness and Loneliness as Serial Mediators
Authors: Bekir Seyhan , Mancı Egemen , Hürman İpek Ergönül , Makas Samet , Batmaz Hasan , Dombak Kübra
Published: February 2025

Background: This study aimed to understand how insomnia problems experienced by esports athletes affect their life satisfaction and to elucidate the mechanisms underlying these effects. It is thought that psychological factors such as mindfulness and loneliness may mediate the relationship between insomnia and life satisfaction. Understanding the insomnia experienced by esports athletes and reducing the effects of these problems is important to increase their performance and improve their health and well-being. Methods: The study data were obtained from 340 participants, 297 (87.4%) male and 43 (12.6%) female, with an average age of 18.90 (sd=2.35). The explored the serial mediating roles of mindfulness and loneliness between insomnia and life satisfaction in esports athletes and correlational research derived from quantitative methods. Furthermore, the convenience sampling method was chosen for data collection. Results: The findings illuminate a nuanced interplay among insomnia, mindfulness, loneliness, and life satisfaction in the context of esports athletes. Life satisfaction was found to be negatively correlated with both insomnia and loneliness, and positively correlated with mindfulness, indicating that higher levels of insomnia and loneliness are associated with lower life satisfaction, whereas greater mindfulness correlates with higher life satisfaction. Conclusions: This study focused on the psychological interaction of insomnia, mindfulness, loneliness, and life satisfaction in esports athletes. Its approach this study thus fills a significant gap in both the esports psychology literature and the practical management of esports athletes' mental health, positioning itself as a valuable resource for researchers, practitioners, and policymakers interested in the intersection of competitive sports.
The Blood-Labyrinth Barrier: Non-invasive Delivery Strategies for Inner Ear Drug Delivery
Authors: Yi Zhangyi , Wang Xiaoying , Yin Ge , Yu Sun
Published: February 2025

Keywords: blood-labyrinth barrier; cochlear; drug delivery; stria vascularis; hearing
The COVID-19 Infection Did Not Aggravate the Mortality of Long-Term Care Facility Residents Under Strict Infection Control and with Immediate Anti-Viral Treatment: Real World Analysis
Authors: Shimizu Hideyasu , Kawase Jin , Higashi Yuko , Nabeno Hiroyuki , Hayashi Masamichi , Imaizumi Kazuyoshi , Ito Yuji , Matsunaga Masaaki , Okazawa Mitsushi
Published: February 2025

Between January 2022 and December 2023, the Toshiwakai long-term care facility (LTCF) experienced a COVID-19 cluster. Among 231 infected residents, 253 episodes were identified, including 20 residents who were reinfected once and one who was reinfected twice. The strict infection control operation and antiviral treatments were promptly administered; however, four residents died, and five were hospitalized within 10 days (two due to fractures). Most symptomatic cases resolved within 10 days. A comparison of mortality rates between infected and uninfected residents showed no statistically significant differences, underscoring the effectiveness of robust infection control measures and prompt antiviral therapy in mitigating the adverse outcomes of COVID-19. Mortality trends were analyzed across three periods: Period 1 (pre-COVID-19, 2018–2019), Period 2 (COVID-19 present in Japan but absent in our facility, 2020–2021), and Period 3 (Omicron-driven cluster, 2022–2023). Mortality rates in Periods 1 and 2 were comparable, whereas Period 3 unexpectedly demonstrated lower mortality despite Omicron's high transmissibility. Although further research is warranted, enhanced infection control measures may also mitigate other severe infections among high-risk populations, such as the elderly and immunocompromised individuals. Additionally, the viral dynamics during the Omicron surge, including potential suppression of other viral pathogens, may have contributed to these outcomes. These findings emphasize the critical role of proactive clinical and public health strategies in managing COVID-19 outbreaks in long-term care settings.
Exploring the Structure-Activity Relationship of Bentonites for Enhanced Refinement of Recycled Vegetable Oil
Authors: Mannu Alberto , Castia Simona , Petretto Giacomo Luigi , Garroni Sebastiano , Castiglione Franca , Mele Andrea
Published: February 2025

The use of bentonite for recycling vegetable oils presents challenges, as even minor variations in the clay composition and structure can lead to significant differences in its ability to retain various chemical groups. This study investigates the structure-activity relationship of four bentonites—two hydrophilic and two hydrophobic (both in commercial and ground forms)—to better understand these effects. Solid-state NMR spectroscopy revealed subtle differences between hydrophobic and hydrophilic materials, as well as distinctions between ground and unground hydrophilic clays, through 29Si and 27Al experiments. These structural variations directly influenced the bentonites' capacity to retain specific chemical groups, which in turn affected the pour point and volatile profile of the processed oils. A Simplex-Lattice design of experiments, combined with multivariate analysis, facilitated the development of a predictive model to optimize process efficiency. Remarkably, this model achieved an improvement in pour point of up to 14.5 °C (from -2 °C to -16.5 °C) for oils treated with hydrophilic unground bentonite. This research underscores the critical role of bentonite morphology in enhancing the efficiency of vegetable oil recycling.
Dependencia emocional e índice de violencia hacia la mujer en Arequipa, Perú
Authors: Calizaya-López José , Alemán-Vilca Yaneth , Carita-Choquecahua Ariosto , Ortiz-Cansaya Segundo , Cervantes-Chávez Laura , Cáceres-Luna Gabriela
Published: February 2025

Introducción: La dependencia emocional es una conducta adictiva y se presenta como un problema psicosocial en la relación de pareja siendo un factor importante para desarrollar la violencia hacia la mujer. Objetivos: Analizar la relación de la dependencia emocional e índice de violencia hacia la mujer en Perú, y comparar la dependencia emocional e índice de violencia hacia la mujer según variables sociodemográficas de las participantes. Método: El estudio fue correlacional, cuantitativo, no experimental de corte transversal. Participaron 1236 mujeres elegidas intencionalmente a partir de haber experimentado alguna forma de violencia en la relación de pareja. Se utilizaron dos instrumentos de medición validados para identificar la dependencia emocional y la violencia hacia la mujer, además, se incluyó información sociodemográfica (edad, ámbito de residencia, nivel de escolaridad, ocupación, y relación sentimental). Para el análisis de datos se utilizaron pruebas no paramétricas Resultados: Se halló correlación significativa positiva baja entre las variables, el índice de violencia es severo en la mayoría de las participantes y el nivel de dependencia emocional hacia la pareja fue de nivel moderado. Conclusiones: La dependencia emocional es una variable que apertura el incremento de la violencia hacia la mujer, por tanto, de acuerdo con las variables sociodemográficas son las mujeres más jóvenes y que residen en el ámbito urbano, las más dependientes emocionalmente, asimismo, la violencia hacia la mujer es un problema social que no distingue a ninguna mujer de ser potencialmente víctima de violencia, siendo las mujeres adultas que mantienen una relación con la pareja y dependen económicamente las más expuestas a la violencia severa.
Evaluación tridimensional de las características de impactación de caninos mandibulares y su relación con la morfometría de raíces de incisivos inferiores
Authors:   , Mejia Milian Mabel
Published: February 2025

"Objetivo: Evaluar tridimensionalmente las características de la impactación del canino mandibular con la morfometría de las raíces de los incisivos inferiores. Materiales y métodos: Fueron evaluadas tomografías computarizadas de haz cónico (TCHC) de 35 individuos (18 varones y 17 mujeres) con una edad media de 14.37± 10.26 años. En ellas se evaluaron 43 caninos mandibulares impactados (CMbI). En seguida, se determinó su localización, sector y nivel de impactación, y se midieron las distancias de los caninos al plano oclusal, las angulaciones con respecto a la línea media y a los incisivos laterales adyacentes, la longitud de los caninos impactados, y de los incisivos inferiores y finalmente se determinó la presencia de reabsorción radicular de incisivos. Posteriormente, se evaluaron las asociaciones entre el tipo, sector, nivel y proximidad de impactación con la condición de resorción radicular y se compararon las longitudes radiculares entre los tipos, sectores y niveles de impactación. Las pruebas de chi cuadrado y Kruskal Wallis fueron empleadas (P<0.05). Resultados: La posición bucal del canino mandibular impactado fue la más predominante (65.1%), la ubicación por debajo del tercio medio apical de la raíz de los incisivos inferiores fue la más frecuente (32.6%). La proximidad del folículo y la corona de los CMbI no afectaron la estructura de la raíz de los incisivos inferiores, produciendo una ausente o leve reabsorción radicular (hasta 17.9% en el incisivo lateral izquierdo). El 72.1% y el 52.2% no presentaron contacto del canino impactado o de su folículo con el diente adyacente respectivamente. Las longitudes radiculares fueron similares en los distintos tipos de impactación (P>0.05).
Conclusión: El canino mandibular impactado mayormente se encuentra posicionado por bucal y por debajo del tercio medio apical de la raíz de los incisivos inferiores..."
Education, Party Membership, and Occupational Status Attainment in China's Social Transformation (1950-2017)
Authors: Wang Fuqin
Published: February 2025

Previous researches on the occupational status attainment among Chinese residents have predominantly employed grouped regression analysis, which categorizes data according to significant historical events. This approach explores how variables such as education and party membership influence status attainment across different time periods. However, it often overlooks the heterogeneity of effects within these groups. To address this gap, the present study utilizes urban sample data from the "China General Social Survey (CGSS)" spanning from 2003 to 2017(n=43,235)1. It segments the population into 68 cohorts based on individuals' year of entry from 1950 to 2017, thereby concentrating on the evolving impacts of education level and party membership on occupational status attainment post the establishment of New China. The findings reveal a continuous overall increase in average occupational status since the founding of New China. Both education level and party membership positively correlate with status attainment; however, their relative significance exhibits considerable variation across different eras. These results both corroborate and challenge prior studies concerning status attainment. While the method of grouped regression analysis based on major historical events effectively captures the general shift from a redistributive to a market economy, it fails to sufficiently account for the nuanced impacts of social change on occupational status attainment. This study underscores the need for more detailed analyses to comprehensively understand these dynamics.
WITHDRAWN: Appraisal of carbon emissions from logistic processes and prevented by initiatives in the local community
Authors: Snizhkovska Liliia , Sós Eszter , Wang Bohong
Published: February 2025

The full text of this preprint has been withdrawn by the authors since they no longer stand by the findings/conclusions of this work. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author.
The overlooked conservation value and ecosystem services of saline lakes
Authors: Burian Alfred , Wilson Ramesh , Karimov Bakhtiyor , Timms Brian , Kulshreshtha Seema , Golovatuyk Larisa , Kalioujnaia Irina , Zechmeister Thomas , Teubner Katrin , Krienitz Lothar , Sanchez Marta , Farias Maria Eugenia , Melack John M , Lipka Oksana , Coleman Peri , Cavicchioli Ricardo , Hueso-Kortekaas Katia , Shadrin Nickolai , Anufriieva Elena , Ulanova Svetlana , Namsaraev Zorigto , Sima Somayeh , Schagerl Michael , Ryves David , Casamayor Emilio , Rogers Christopher , Poikane Sandra , Kokorite Ilga , Komova Anastasia , Matyugina Evgeniya , Boros Emil , Camacho-Santamans Alba , Camacho Antonio , Santamans Anna , Morant Daniel , Anderson Tania , Barbosa Luciana Gomes , Bucher Enrique , Fetahi Tadesse , Selivanova Elena , Hudson Peter , Moreno Edmumdo , Colla María , Datson Bindy , Abram Ors , Mills Keely , Wurtsbaugh Wayne , Baxter Bonnie , Larson Ron , Zapitis Charitos , Chao Xiaobo , Kratina Pavel , Zhang Can , Beckmann Michael , Vignatti Alicia , Echaniz Santiago , Johnston Jill , Alfonso María , Quini Nicolás Vidal , Balci Nurgül , Durand Javier Alcocer , Mauvisseau Quentin , Oren Aharon , Bazhenov Yuri , Bazarova Balzhit , Afonina Ekaterina , Tashlykova Natalya , Borzenko Svetlana , Tsybekmitova Gazhit , Zadereev Egor
Published: February 2025

Saline lakes are hypersensitive to changes in their water balance and therefore show amplified responses to climatic and land-use changes in their catchment. However, despite the resulting, often dramatic ecological consequences, saline lakes rank low on policy agendas as they are assumed to support few ecosystem services and low levels of biodiversity. Here, we challenge this view and evaluate ecosystem services and threatened species in 84 saline lakes distributed across the globe. We found that saline lakes harbour not only threatened aquatic biota but also a diverse range of red-listed terrestrial species that critically rely on the lakes’ existence. Further, our results highlight that saline lakes support, irrespective of their salinity, a number of culturally and economically important ecosystem services. We conclude our analysis with best-practice recommendations for sustainable management of saline lakes. Their local adaptation and implementation will be key for safeguarding biodiversity and ecosystem services of these valuable but highly sensitive ecosystems.
Land Use Changes and Air Quality Impacts on Environmental Sustainability: A Case Study of Salem District, Tamil Nadu, India
Authors: Junaid S. Mohammed , Ilaiyarasan M.
Published: February 2025

This study aims to examine land use changes in Salem District from 1995 to 2024 using Geospatial techniques. It reveals shifts due to urbanization, agricultural expansion, deforestation, and conservation efforts. Urban areas expanded, while cropland and forests decreased. Positive trends, such as the recovery of water bodies and wastelands, are noted. The study assesses environmental impacts like air quality and pollution from industrial and vehicular activities. By linking LULC changes to pollution hotspots, it highlights the necessity for sustainable land management and urban planning. This analysis delivers important insights and recommendations for mitigating environmental impacts, offering policy-oriented strategies for researchers, policymakers, and planners.
Redressal Mechanisms Against Sexual Harassment in an Indian University: A SWOT Analysis
Authors: Singh Jaspreet , Singh Ranvir
Published: February 2025

Women face various forms of discrimination as well as harassment, some of which is sexually oriented and directly impact the dignity and identity of women. In contemporary era when women are entering to all unconventional work profiles, proactive measures are needed more than ever to safeguard against such harassment. This study made an assessment for stakeholder’s awareness, procedural ramification and Internal Complaint Committee’s (ICC) functioning in an Indian University, through qualitative approach. A SWOT analysis was done for institutional redressal mechanism against sexual harassment. Study revealed that ICC is lacking in the areas where institution can play significant supportive roles. Overall, the biggest concern emerged about the compromised autonomy of the ICC.
The ‘π-Trap’ as an Unrestricted Crystal Sponge for Inherently Amorphous Cluster Compounds
Authors: Dehnen Stefanie , Wang Yaofeng , Rinn Niklas , Eberheim Kevin , Ziese Ferdinand , Christmann Jan , Sanna Simone
Published: February 2025

Single crystal diffraction is one of the most common and powerful tools for structural elucidation in science. However, obtaining single crystals of adequate size and quality is not always trivial, with some chemicals inherently resisting all attempts. The ‘crystalline sponge’ method has attracted a lot of attention for crystallizing otherwise intrinsically amorphous compounds inside a metal organic framework (MOF).1,2 However, its application is limited by the size and stability of the pores within the networks. In this study, we propose a novel ‘unrestricted crystalline sponge’ method, which we denominate as the ‘π-trap’. It makes use of π-π interactions between C60 and nm-sized molecules that by themselves do not form crystalline compounds. Using this technique, we successfully crystallized adamantane-like organic-inorganic hybrid clusters, which exhibit extreme nonlinear optical properties only within the amorphous habitus, and resist any attempt for crystallization. As the clusters' low tendency to order in the long range was successfully overcome by the strong C60···cluster interactions in the ‘π-trap’, we were able to precisely determine their molecular structures. As we could show by optical spectroscopy and quantum chemical calculations, both the clusters and C60 behave like being dissolved in the other component, including the formation of cluster pairs previously proposed by theoretical studies and low-angle scattering experiments on amorphous samples. We propose that the described method is applicable to all kinds of amorphous compounds that allow for π-π interactions, without the size restrictions facing the ‘crystalline sponge’ method, especially when considering the usage of larger fullerenes.
Hepatocyte growth factor/c-MET signaling is associated with gestational diabetes (GDM) and GDM complications: a case control study
Authors: Jung Ye Won , Lee Mina , Ko Young Bok , Song Soo Youn , Yoo Heon Jong , Kang Yea Eun , Kim Ok Soon , Kang Byung Hun , Kim Hyun Jin
Published: February 2025

Background
Hepatocyte growth factor (HGF)/mesenchymal-epithelial transition factor (c-MET) signaling is involved in glucose homeostasis in pancreatic β cells; however, studies on its relationship with gestational diabetes mellitus (GDM) are lacking. This study aimed to investigate HGF and its receptor, c-MET, in pregnant women with GDM and to analyze the correlation between HGF/c-MET signaling and GDM complications.
Methods
In total, 44 pregnant women with normal glucose tolerance (NGT) and 32 with GDM were studied. Serum levels of HGF and c-MET were measured using an enzyme-linked immunosorbent assay. The relative mRNA expression of HGF and c-MET was measured using real-time polymerase chain reaction. The protein expression of HGF and c-MET in placental and visceral fat tissues was measured using western blot analysis. Logistic regression and Pearson’s correlation analyses examined the associations of these variables with clinical information.
Results
Serum sc-MET levels were significantly higher (1472.58 vs. 1651.23 ng/mL, p < 0.001) and cord blood HGF levels were significantly lower (370.76 vs. 254.54 ng/mL, p = 0.042) in the GDM group than in the NGT group. The area under the receiver operating characteristic curve for sc-MET was 0.744 (95% confidence interval: 0.632–0.857, p < 0.001). The cut-off serum sc-MET level for predicting GDM was 1455.26 ng/mL. HGF protein expression in the maternal visceral fat tissue was significantly higher in the GDM group than in the NGT group (2-fold higher, p < 0.05). Serum HGF significantly correlated with cord arterial blood gas analysis (ABGA) base excess (r =-0.390, p = 0.007) and cord ABGA lactic acid (r = 0.469, p = 0.001). Cord blood HGF levels were significantly correlated with cord blood glucose levels (r = 0.439, p = 0.002).
Conclusions
We found an increase in serum sc-MET, a decrease in cord HGF, and an increase in HGF protein expression in the visceral fat tissue of the GDM group, indicating that HGF/c-MET signaling is related to GDM expression. In addition, maternal serum HGF levels correlated with base excess and lactic acid levels in cord ABGA, and cord blood HGF levels correlated with cord blood glucose levels. These outcomes suggest that HGF/c-MET signaling may have potential application in predicting GDM complications.
Notch, β-catenin and MAPK signaling segregate endoderm and mesoderm germ layer identities in the diploblast Nematostella vectensis
Authors: Technau Ulrich , Haillot Emmanuel , Lebedeva Tatiana , Steger Julia , Genikhovich Grigory , Montenegro Juan , Cole Alison
Published: February 2025

A recent study suggested that morphologically diploblastic sea anemones (Cnidaria) have three segregated germ layer identities corresponding to the bilaterian germ layers. Here, we investigated, how these germ layer identities are specified during early development of the sea anemone Nematostella vectensis. Our gene expression analysis shows that the mesodermal territory is specified at the animal pole at 6 hours postfertilization, followed by the specification of the definitive endoderm between mesoderm and ectoderm. We then assessed the role of β-catenin, MAPK and Notch signaling during mesoderm and endoderm formation. We show that the mesodermal marker genes are activated by MAPK signaling while being repressed elsewhere by β-catenin signaling. Delta-expressing mesoderm then signals to Notch-expressing ectoderm inducing the definitive endoderm domain at the mesoderm/ectoderm interface. Gain- and loss-of-function experiments showed that Notch signaling is necessary and sufficient for endoderm induction. Based on our results, we propose a model of germ layer specification in Nematostella defined by a crosstalk of MAPK, β-catenin and Notch signaling. Given the similarity of the germ layer specification between the sea anemone and echinoderms, we propose that triploblasty may have predated the split of cnidarians and bilaterians.
Dissecting Genetic Architecture of Flowering and Maturity Traits in Soybean Using GWAS in Indian Environment
Authors: Raghuvanshi Rishiraj , Kumawat Giriraj , Kavishwar Rucha , Gupta Sanjay , Chitikineni Annapurna , Chandra Subash , Satpute Gyanesh K. , Nataraj Vennampally , Varshney Rajeev K , Nguyen Henry , Rajesh Vangala , Maranna Shivakumar , Kuchlan Mrinal K. , Kuchlan Punam , Singh Ajay K. , Singh K.H. , Ratnaparkhe Milind B.
Published: February 2025

Background
Soybean (Glycine max [L.] Merril) is a photoperiod-sensitive crop, with traits like days to flowering, days to maturity playing crucial roles in its adaptability and yield. These traits are regulated by genetic networks controlling flowering time and environmental adaptation, making their genetic basis as an essential knowledge for breeders aiming to improve yield and adaptability. In this study, a Genome-Wide Association Study (GWAS) was conducted for Days to flowering (DTF), days to maturity (DTM) by using FarmCPU, BLINK and MLM model on 254 diverse soybean genotypes over four consecutive years (2019–2022) to dissect genetic architecture for flowering and maturity traits in an Indian Environment.
Results
In this study, GWAS identified 20 significant loci for days to flowering and maturity, among them 12 are new and 8 were previously reported loci. Among the 12 newly identified loci, a significant locus, Lee.Gm03-3 on chromosome 03, is associated with days to flowering and linked with SNP markers S3_46108324 and S3_46108342. We also identified key candidate genes for Lee.Gm03-3, include Glyma.03G227300 (circadian rhythm and photomorphogenesis, Phytochrome region) Glyma.03G225000 (circadian rhythm, gibberellic acid signaling, red/far-red light signaling), Glyma.03G219100 (cytokinin signaling, embryo sac development), and Glyma.03G226000 (meristem initiation). These genes are vital for light-response and developmental pathways. In addition, we also validated eight previously known genes E2, E4, E9, E11, E10/FT4, PRR7/Tof12, Dt1, and Dt2 that influence flowering and maturity in Indian environment.
Conclusions
This study advances understanding of the genetic basis underlying photoperiod sensitivity related genes for circadian rhythm and photomorphogenesis, gibberellic acid signaling, red/far-red light signaling in soybean and highlights potential targets for genetic improvement of flowering maturity duration and adaptability of soybean under Indian environment.
Unterschiedliche Menschen wollen auch unterschiedlich teilnehmen
Authors: Eggert Susanne , Jäntschi Katharina
Published: February 2025

Im Interview erläutert die Geschlechterforscherin Katharina Jäntschi, wie das Beteiligungsverfahren beim Bayerischen Aktionsplan QUEER aufgebaut und gestaltet ist, was dabei gut funktioniert und wo es Hürden gibt. Auch ein Shitstorm spielt dabei eine Rolle, den das Projektteam letztlich für einen zusätzlichen Bildungsauftrag genutzt hat.
Qualitätvolle Ansätze für eine rassismuskritische Medienpädagogik
Authors: Aberl Daniel
Published: February 2025

Im Rahmen meiner Masterarbeit zum Abschluss des Studiengangs ‚Handlungsorientierte Medienpädagogik‘ an der Universität für Weiterbildung Krems habe ich qualitätvolle Ansätze für eine rassismuskritische Medienpädagogik untersucht. Für dieses Unterfangen wurden insgesamt sechs Expert*innen interviewt und die Gespräche mithilfe einer qualitativen Inhaltsanalyse ausgewertet. Die zentralen Erkenntnisse werden im ­ Folgenden dargelegt.
19. Shell Jugendstudie – Pragmatisch zwischen Verdrossenheit und gelebter Vielfalt
Authors: Giebisch Antonia
Published: February 2025

Bei den Jugendlichen in Deutschland ist ein wachsendes politisches Interesse deutlich spürbar, wie die 19. Shell Jugendstudie zeigt. So interessieren sich 55 Prozent der Studienteilnehmenden für politische Themen und rund die Hälfte (51 %) informiert sich aktiv darüber. Zudem positioniert sich eine zunehmende Zahl im politischen Spektrum, wobei sich 25 Prozent dem rechten und 41 Prozent dem linken Lager zuordnen. Auch die Digitalisierung prägt den Alltag der jungen Generation: ­ Digitale Medien werden vor allem zur Kommunikation (95 %), für Unterhaltung (67 %) und für Bildungsinhalte (69 %) genutzt. Dabei bleibt das Vertrauen in klassische Medien hoch – 83 Prozent der Jugendlichen schätzen die Nachrichtenangebote von ARD und ZDF, und 80 Prozent empfinden überregionale Zeitungen als vertrauenswürdig. Im Gegensatz dazu genießen Plattformen wie YouTube, TikTok und Instagram weniger Vertrauen, verzeichneten insgesamt über die letzten Jahre jedoch einen Vertrauenszuwachs. Zudem wünschen sich 90 Prozent der Jugendlichen eine verstärkte Einbindung digitaler Medienkompetenz und den Umgang mit Fakenews im Schulunterricht. Auch das Interesse an Bildung zu KI nimmt zu. Zwar stehen 47 Prozent der Studienteilnehmenden dieser Technologie positiv gegenüber und hoffen, dass sie den Alltag erleichtert (69 %) und in Bereichen wie Medizin und Bildung Fortschritte ermöglicht (60 %), doch zwei Drittel äußern Bedenken, dass KI aufgrund fehlender Empathie unmenschliche Entscheidungen treffen könnte.
Die Studienergebnisse beruhen auf einer Befragung von 2.509 Jugendlichen im Alter von 12 bis  25 Jahren aus ganz Deutschland, ergänzt durch vertiefende Leitfadeninterviews mit 20 Jugendlichen, die tiefere Einblicke in ihre Lebenssituation, Einstellungen und Orientierungen geben.
https://shell.de
Lese- und Sprachförderung unter Wasser
Authors: Müller Marcus
Published: February 2025

paedalogis (2024). Kuno taucht ab. App für Tablets, Android/iOS, 1,99 €.
Zusammen mit Kater Kuno kann man sich in der App Kuno taucht ab in ein Leseabenteuer begeben, das zu Recht mit dem Pädagogischen Medienpreis 2024 ausgezeichnet wurde. In einer wunderbar absurden wie auch schönen Bildergeschichte können sich Leseanfänger*innen durch die interaktive Geschichte klicken. Der Kater im Matrosenhemd trägt bei seinen Tauchgängen einen Tauchtopf (eine Art Kochtopf) auf dem Kopf. Klar, wie sonst sollte ein Kater unter Wasser atmen? Mit ähnlicher Selbstverständlichkeit können Kinder die ersten Schritte zum Lesenlernen machen und sich in die Welt der Buchstaben, Silben und Wörter begeben.
In der App kann man Kater Kuno bei seiner Reise zu seiner Tante Tea begleiten. Am Ende hält diese eine kleine Überraschung für ihn bereit. Doch zuvor begegnen den Kindern am Bildschirm viele kleine Rätsel und die Reise ist mit verschiedenen Entscheidungspfaden gespickt, sodass Kinder sich mehrmals durch die Geschichte klicken können, ohne dass es langweilig wird. Positiv ist hervorzuheben, dass in den Rätseln gezielt mögliche Schwierigkeiten angegangen werden, die viele Leseranfänger*innen haben. So sollen Kinder bei einem Rätsel einen Hai mit Gegenständen füttern, aber dabei beachten, dass der Hai nur Dinge futtert, die mit K beginnen. So kommt das Gummibärchen mit dem Anfangsbuchstaben G nicht in Frage, der Käse mit K ist hingegen in Ordnung. So üben Kinder spielerisch, zwischen den Plosivlauten k und g zu unterscheiden. Darüber hinaus müssen Reimpärchen gefunden werden, was ebenfalls eine wichtige Kompetenz für alle Leseanfänger*innen ist.
Es sind etwa 350 Lesewörter in der Geschichte enthalten. Dabei kann jederzeit jedes Wort angetippt und vorgelesen werden. Insgesamt zeigt sich beim Spielen des Abenteuers, dass nicht nur Lesekenntnisse, sondern auch Neugier und Freude am Ausprobieren Teil eines Erfolgsrezepts sein können, um die Geschichte bis zum Ende durchzuspielen. So können Kinder sich jederzeit Tipps geben lassen und sich sowohl als etwas fortgeschrittene Leseanfänger*innen als auch als Neulinge an dieses Abenteuer wagen.
Auf der Website finden sich weitere didaktische Anregungen zur App. So stehen zum Beispiel Memorykarten oder kleine Papierfiguren von Kuno und den anderen Charakteren zum kostenlosen Download und Ausdruck zur Verfügung, sodass Kinder die Lesereise analog nachspielen und so die Worte aus der Geschichte wiederholen können.
https://paedalogis.com/kuno
Kramp, Leif & Weichert, Stephan (2025). Resilienz in der digitalen Gesellschaft. Mediennutzung in Zeiten von Krisen, Kriegen und KI. Köln: Herbert von Halem. 198 S., 24,00 €.
Authors: Giebisch Antonia
Published: February 2025

Leif Kramp und Stephan Weichert untersuchen in ihrem Werk, wie die Digitalisierung und aktuelle Krisen die Mediennutzung, die demokratische Stabilität und die individuelle Widerstandsfähigkeit beeinflussen. Sie betonen dabei die Bedeutung digitaler Resilienz als zentrale Kompetenz, um den Herausforderungen einer zunehmend vernetzten Gesellschaft begegnen zu können.
Im Buch wird die zunehmende Nachrichtenvermeidung aufgearbeitet, die häufig durch digitale Überforderung oder ein schwindendes Vertrauen in journalistische Inhalte hervorgerufen wird. Diese Entwicklung gefährdet sowohl den öffentlichen Diskurs als auch die demokratische Stabilität. Gleichzeitig beleuchten die Autoren die ambivalente Rolle der Digitalisierung: Soziale Netzwerke können zwar Vernetzung und Engagement fördern, doch viele Nutzer*innen akzeptieren dabei bewusst die potenziell gravierenden gesundheitlichen und sozialen Folgen.
Abschließend präsentieren die Autoren konkrete Handlungsempfehlungen, die von Herausforderungen digitaler Mediennutzung bis hin zu Handlungsempfehlungen zum Thema digitale Resilienz als soziale Medienkompetenz reichen. Das Buch verbindet eine fundierte theoretische Grundlage mit empirischen Erkenntnissen aus repräsentativen Befragungen und qualitativen Interviews. Praxisnahe Beispiele verdeutlichen, wie tief digitale Medien in das Leben der Menschen eingreifen.
Mit ihrer differenzierten Analyse der Wechselwirkungen zwischen Digitalisierung, Mediennutzung und gesellschaftlicher Resilienz gelingt es Kramp und Weichert, ihre Leser*innen für die komplexen Zusammenhänge zu sensibilisieren und ein tieferes Verständnis für dieses hochaktuelle Thema zu schaffen.
Digital Detox– Abschalten im Urlaub
Authors: Mellitzer Sophia
Published: February 2025

„Sonne im Gesicht, Italienisch im Kopf, Eis in der Waffel, Füße im Meer – wir sind angekommen im Urlaub an der Adria! Ich lege mein Smartphone für eine Woche zur Seite und befinde mich ganz im Hier und Jetzt. A presto e tanti saluti d‘Italia!”
Mit einer Nachricht wie dieser verabschiede ichbmich jedes Jahr in den sommerlichen Digital Detox. Schon Wochen vorher steigt meine Vorfreude auf diese Auszeit. Denn damit entbinde ich mich jeglicher Erwartungen, Verpflichtungen und Zwänge, die mit dem Gerät verbunden sind. Eine Schulfreundin hat Geburtstag? Sie weiß, dass sie keinen Anruf von mir bekommt. Im örtlichen WhatsApp-Familienchat werden die Regeln nicht eingehalten? Die anderen Admins übernehmen. Ein wunderschöner Sonnenuntergang mit Flamingos am Himmel lädt zum Fotografieren ein? Das Bild speichere ich in meinem Kopf ab.
Ich beobachte mich dabei, wie ich mein ­ Tempo verlangsame. Und nicht mehr so viele Dinge gleichzeitig tue. Ich lese. Ich suche Muscheln. Ich schaue in die Luft. Ich habe die Kinder im Blick. Ich unterhalte mich mit den Einheimischen. Mir ist ein bisschen langweilig. Das ist echt selten. Wie schön! Ich beobachte, wie die Menschen um mich herum ihr Smartphone nutzen. Mein Mann ist in die Nachrichten vertieft. Strandgäste telefonieren lautstark. Großeltern filmen ihre Enkel beim Planschen. Jugendliche hören Musik über die Bluetooth Box. Und unser befreundetes Pärchen stellt witzige Memes in unsere Urlaubsgruppe und kichert sofort los.
Ab und zu fehlt mir mein Smartphone. „Was heißt nochmal Pflaster auf Italienisch?” frage ich mich auf dem Weg zum Strandaufseher. Der blutende Zeh unseres Kindes bedarf keiner Erklärung. Die Kinder haben eine großartige Sandburg gebaut. „Kannst du bitte ein Foto davon machen?” bitte ich unsere Freundin. Eines Morgens heißt es: „In welche Stadt wollen wir heute einen Ausflug machen?”. Fragt mich nicht, ich mache Digital Detox! Keine Internetrecherche in diesem Urlaub. Ich zwinge mich, loszulassen. Die anderen Erwachsenen dürfen das organisieren. Nach einer Dreiviertelstunde Fahrt in Richtung Klein-Venedig runzle ich die Stirn: „Sind das da hinten Gewitterwolken?”. Wir steuern direkt auf eine Regenfront zu. Es hat wohl niemand von uns die Wetter-App gecheckt? Klar, das mache sonst meistens ich! Vom Parkplatz aus schaffen wir es gerade noch, einen freien Tisch unter einer großen Markise einer Pizzeria am Kanal zu erwischen. Dort sitzen wir über zwei Stunden fest. Es ist irgendwie gemütlich, wie der Regen um uns herum vom Himmel strömt. Die Kinder spielen zwischen den Tischen. Ich gönne mir ein leckeres Tiramisu. Wann habe ich sonst mal Zeit für einen Nachtisch? Hach, schon toll, meine Digital-Detox-Woche. Auch wenn ich mir zugegebenermaßen manches davon ein klein wenig schönreden muss. ;-)
#77 – Sichtbarkeit von Frauen* in der Wissenschaft mit Prof. Dr. Judith Ackermann und Anne Gerlieb
Authors: Struckmeyer Kati , Ackermann Judith , Gerlieb Anne
Published: February 2025

Warum sind Wissenschaftlerinnen im Wissenschaftsjournalismus und in der Wissenschaftskommunikation unterrepräsentiert? Und wie lässt sich das ändern? Diesen Fragen widmet sich das Projekt WIM | Wissenschaftlerinnen in die Medien. Prof. Dr. Judith Ackermann, Leiterin des Projekts und Anne Gerlieb, wissenschaftliche Mitarbeiterin, geben spannende Einblicke in dieses komplexe und hochaktuelle Thema. Denn gerade jetzt ist die Vielfalt der Perspektiven gefragt!
Der Einfluss des Interleukin-1-Signalwegs in Hepatozyten auf die metastatische Nische in Bezug auf Lebermetastasen des kolorektalen Karzinoms
Authors:   , Hausdorf Anna
Published: February 2025

Das kolorektale Karzinom gehört zu den häufigsten Krebserkrankungen und Krebstodesursachen in Deutschland. Lebermetastasen treten bei vielen Patientinnen und Patienten auf und beeinträchtigen die Prognose erheblich.
Für die Entstehung des kolorektalen Karzinoms ist die Interaktion zwischen Tumorzellen und dem umgebendem Gewebe entscheidend. Dieses umgebende Gewebe wird als Tumormicroenvironment bezeichnet. Es beinhaltet molekulare Komponenten wie Cytokine und verschiedene Zelltypen wie Immun- und Stromazellen. Auch für die Entstehung von Lebermetastasen ist ein komplexes Zusammenspiel zwischen Tumorzellen und Lebergewebe nötig, welches als metastatische Nische bezeichnet wird. Hepatozyten sind über verschiedene Mechanismen an der Bildung der metastatischen Nische beteiligt.
Sowohl im Tumormicroenvironment als auch für die metastatische Nische spielen Immun- und Entzündungsreaktionen eine große Rolle. Interleukin-1 (IL-1) ist ein proinflammatorisches Cytokin, das an verschiedenen entzündlichen Prozessen beteiligt ist, so auch im Tumormicroenvironment. Unklar ist jedoch, wie die Interaktion zwischen IL-1 und den Hepatozyten die metastatische Nische beeinflusst.
Ziel der durchgeführten Arbeit war deshalb, zu untersuchen, wie der IL-1-Signalweg in Hepatozyten die Entwicklung von Lebermetastasen des kolorektalen Karzinoms beeinflusst.
Um einen Hepatozyten-spezifischen Knockdown des Interleukin-1 Rezeptors 1 (IL-1R1) zu generieren, wurden FAH(-/-)-Cas9-Mäuse verwendet. Den Mäusen wurden daraufhin Tumororganoide orthotop ins Kolon transplantiert. Nach Anwachsen der Tumore im Kolon sollten die Lebern der Mäuse auf Metastasen untersucht werden. Die Tumore wuchsen zunächst im Kolon der Mäuse an, wurden jedoch nach kurzer Zeit abgestoßen. Metastasen konnten demnach nicht untersucht werden. Die vorliegende Arbeit diskutiert daher auch mögliche Gründe für die Abstoßung.
LANGUAGE AS A TOOL FOR DEFINING GENERATIONS: A STUDY ON GEN-Z LINGO
Authors:   Lecturer, Department of English, Prime University., Yeasmin Sayma
Published: February 2025

This study aimed at exploring the relationship between the language in practice and the generational identity, based on the use of generation-specific jargon in a specific generation of bilingual participants. Language and identity is a prominent subject matter in linguistic studies. The core objective of this paper was to establish language as a metaphor for generation or to examine the fluidity of language with the course of time. It also attempted to break down the conventional idea of defining generation through biological age, rather held generation as a relative term depending on the linguistic behavior in the relevant contexts. The researcher intended to find out the significant factors behind such variations by adopting a mixed research methodology. Finally, the study made an attempt to answer the research question and thus fulfil the research objective of the study. The findings of the study suggested that there are generation specific jargons that help the people of Generation-Z to establish their generational identity.
COMPARATIVE CARDIAC REGENERATION: ZEBRAFISH VS. HUMAN HEART REPAIR MECHANISMS
Authors:   Under Graduate Student, Bachelor of Pharmacy, Thanthai Roever College of Pharmacy, Perambalur, Tamilnadu, India., Irshath R. , Mariyammal R. ,   Professor, Department of Pharmacology, Thanthai Roever College of Pharmacy, Perambalur, Tamilnadu, India., Nepolean R. ,   Principal, Department of Pharmaceutics, Thanthai Roever College of Pharmacy, Perambalur, Tamilnadu, India., Annadurai Sathya ,   Assistant Professor, Department of Pharmacology, Thanthai Roever College of Pharmacy, Perambalur, Tamilnadu, India.
Published: February 2025

Zebrafish(Danio rerio) can regenerate their hearts, completely after being injured, they have become an important model organism for research on cardiovascular regeneration. Through the proliferation and dedifferentiation of cardiomyocytes, and additional contributions of other cell types such as epicardial cells, endothelial cells, and fibroblasts.Zebrafish may repair significant cardiac injury, in contrast to mammals or humans whose hearts have limited regeneration capacity. Wnt/Î²-catenin, Notch and Hippo signaling are some of the molecular pathways involved in this regeneration process that coordinate the reactivation of cardiomyocytes, proliferation, and the development of new blood vessels. Comparative studies show how Zebrafish and mammals differ greatly in their ability to repair the heart, highlighting how Zebrafish research may help or guide us in regenerative medicine treatments for human heart disease. This analysis looks at the molecular and cellular processes that underlie the betterment of human life threatened by heart surgeries.
Do myxomycete assemblages differ in the forest core vs. its edge? Rapid assessment of a tropical secondary-growth experimental forest in Southern Mindanao, Philippines
Authors:   University of Santo Tomas, University of Southern Mindanaо, N. Buisan Prince Nur-Hakeem , A. Dagamac Nikki Heherson ,   University of Santo Tomas
Published: February 2025

Forest patches and edges resulting from fragmentation brought by various stresses
have increased our understanding of stress effects on the assemblages of various
organisms residing in these habitats, with the degradation of forest ecosystems
often negatively affecting flora and fauna. However, our knowledge of the dynamic
influences of such factors on microorganisms is limited, and little is known about
variations in forest disturbance gradients. Study of myxomycetes in different
habitats and microhabitats offers a bridge to overcome these limitations. The
moist chamber technique was used to compare the myxomycete assemblages of
three forest zones (core, midline, and edge) within an experimental secondarygrowth forest in Cotabato Province. For the analyzed forest, 15 morphospecies
belonging to 7 genera were identified. In addition, it was shown that regardless
of site, forest zone, and sample substrate, alpha diversity values showed no
significant differences. Cluster analysis revealed distinct delineations between
the sampled forest zones—the forest edge and core were more similar than the
forest midline. However, ordination analysis showed no significant differences
in species composition between the sampled forest zones, further suggesting that
the myxomycete assemblages in different forest zones are identical. This research
is the first step toward understanding the continuity of myxomycete assemblages
in anthropogenically affected forest types, helping to fill in the gaps in knowledge
about one of the world’s unexplored research areas.
Os jogos teatrais e a sequência básica de Rildo Cosson na formação do leitor literário no curso de pedagogia
Authors:   , Pinheiro André de Araújo
Published: February 2025

As discussões no tocante à formação leitora têm suscitado, cada vez mais, a necessidade de novas práticas metodológicas no contexto de sala de aula. Nesse sentido, entende-se que o pedagogo, profissional que tece os saberes iniciais no contexto escolar, na vida da criança, deve ter apropriação de fazeres eficazes e, acima de tudo, se permita leitor na atuação da leitura literária. A pesquisa “Os Jogos Teatrais e a Sequência Básica de Rildo Cosson na Formação do Leitor Literário no Curso de Pedagogia” tem por objetivo geral propor uma intervenção de formação leitora literária a partir do diálogo entre os jogos teatrais e a sequência básica de Rildo Cosson, A primeira categoria da discussão teórica é concebida, inicialmente, com Pontes (2012), Candido (1995) e Martins (2006) na discussão da leitura literária, Colomer (2003) e Machado (2016) na formação leitora e, também, Coelho (2000) e PISA (2012; 2015; 2018) na análise da leitura sob a perspectiva dessa pesquisa. A segunda categoria, que versa sobre o letramento literário e a sequência básica, é ombreada nos estudos de Cosson (2007) a respeito da sequência básica e Carlino (2017), Azevedo (2004) e Kleiman (2004) com o letramento acadêmico para as potencialidades do texto literário. Por fim, a terceira categoria teórica traz a perspectiva dos jogos teatrais, em que recorremos a Courtney (2001) para discutirmos o texto dramático em sala de aula e Spolin (2010) e Manzoni (2008) no jogo, criatividade, espontaneidade e improvisação teatral. A pesquisa se constituiu, metodologicamente, numa abordagem de métodos mistos, em que os dados quantitativos são analisados qualitativamente, dada por meio de uma pesquisa intervenção com uma proposta voltada aos graduandos do curso de Pedagogia da Universidade do Estado do Rio Grande do Norte (UERN). O corpus a ser analisado se constituiu de um questionário investigativo, a fim de averiguar como se dão as aulas de formação leitora, e uma proposição de sequência básica com foco na leitura de um poema de Manoel de Barros. Os resultados apontaram a aplicabilidade das etapas das oficinas em uma proposição pensada e vivenciada no/do diálogo entre os jogos teatrais e a sequência básica de Rildo Cosson. Verificamos que os jogos teatrais de improvisação, estímulo composto, fragmentos de texto e círculos concêntricos convergem, respectivamente, com os passos da sequência básica, de motivação, introdução, leitura e interpretação, culminando em uma proposta capaz de formar, prazerosamente, os leitores