bluuebunny/crossref_metadata_2025 huggingface dataset:
Case report: A young man with non-rapid eye movement parasomnias in a KCNT1-related epilepsy family
Authors: Sheng Dandan , Lv Yefan , Li Xinru , Liu Jing , Liu Weiping
Published: November 2023

Differentiating between non-rapid eye movement (NREM) parasomnias and sleep-related hypermotor epilepsy (SHE) is challenging, as they exhibit similar episodes during sleep. A relatively high prevalence of NREM parasomnias has been detected in families with SHE. However, the common pathophysiologic mechanism is not completely clear. There have been no previous reports of KCNT1-related SHE combined with NREM parasomnias. In this report, we describe a 17 years-old male patient from a KCNT1 mutation family who exhibited complex abnormal behaviors during sleep, which have been confirmed as epileptic seizures combined with NREM parasomnias through video-electroencephalogram (vEEG) and video-polysomnography (vPSG). The present article provides a reasoning process to evaluate unusual nocturnal behaviors. Furthermore, our analysis suggests a new potential association between NREM parasomnias and KCNT1 mutations.
Nutritional counseling in athletes: a systematic review
Authors: Fiorini Simona , Neri Lenycia De Cassya Lopes , Guglielmetti Monica , Pedrolini Elisa , Tagliabue Anna , Quatromoni Paula A. , Ferraris Cinzia
Published: November 2023

Many studies report poor adherence to sports nutrition guidelines, but there is a lack of research on the effectiveness of nutrition education and behavior change interventions in athletes. Some studies among athletes demonstrate that nutrition education (NE), often wrongly confused with nutritional counseling (NC), alone is insufficient to result in behavior change. For this reason, a clear distinction between NC and NE is of paramount importance, both in terms of definition and application. NE is considered a formal process to improve a client’s knowledge about food and physical activity. NC is a supportive process delivered by a qualified professional who guides the client(s) to set priorities, establish goals, and create individualized action plans to facilitate behavior change. NC and NE can be delivered both to individuals and groups. To our knowledge, the efficacy of NC provided to athletes has not been comprehensively reviewed. The aim of this study was to investigate the current evidence on the use and efficacy of nutritional counseling within athletes. A systematic literature review was performed based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses method. The search was carried out in: PubMed, Scopus, Web of Science, Science Direct, Cochrane Library between November 2022 and February 2023. Inclusion criteria: recreational and elite athletes; all ages; all genders; NC strategies. The risk of bias was assessed using the RoB 2.0 Cochrane tool. The quality of evidence checking was tested with the Mixed Methods Appraisal Tool system. From 2,438 records identified, 10 studies were included in this review, with athletes representing different levels of competition and type of sports. The most commonly applied behavior change theory was Cognitive Behavioral Theory. NC was delivered mainly by nutrition experts. The duration of the intervention ranged from 3 weeks to 5 years. Regarding the quality of the studies, the majority of articles reached more than 3 stars and lack of adequate randomization was the domain contributing to high risk of bias. NC interventions induced positive changes in nutrition knowledge and dietary intake consequently supporting individual performance. There is evidence of a positive behavioral impact when applying NC to athletes, with positive effects of NC also in athletes with eating disorders. Additional studies of sufficient rigor (i.e., randomized controlled trials) are needed to demonstrate the benefits of NC in athletes.

Systematic review registration

https://www.crd.york.ac.uk/prospero/, identifier CRD42022374502.
Case Report: Bilateral syringocele in an adolescent—area of focus
Authors: Osipov I. B. , Lebedev D. A. , Uzintseva A. A. , Sidorova N. A.
Published: November 2023

Rationale

Cystic dilatation of the bulbourethral gland duct (Cowper's syringocele, CS) is a rare urethral pathology. No more than 150 cases of CS have been reported in the literature, of which the vast majority are children with a unilateral location. Bilateral CS has been reported in eight cases; however, detailed anatomy and clinical manifestations have not been reported. In this study, we report a case of bilateral CS with cavity junctions through the medial septum and its successful minimally invasive treatment in an adolescent.

Case presentation

A 16-year-old adolescent patient complained of painful urination and post-micturition urinary dribbling. Magnetic resonance imaging (MRI), urethrography, and ureteroscopy data enabled the establishment of the diagnosis and determination of the type of CS. The surgical treatment that was performed was endoscopic marsupialization of both CS chambers. At follow-up examination after 7 months, the complaints had ceased, and there was complete normalization of urination. The maximum flow rate during uroflowmetry was 35 ml per second, on voiding cystourethrography, the residual cavities were not contrasted, and there was no residual urine or bacteriuria.

Conclusion

MRI and retrograde urethrography made it possible to visualize changes in the bulbous part of the urethra, and ureteroscopy was the leading imaging modality. These studies was applied precisely because of the suspicion of the presence of a cavity communicating with the urethra. Minimally invasive surgical treatment for double-chamber CS was successful with no resulting complications.
Comparison of clinical outcomes following delivery of budesonide by both vibrating mesh nebulizer and jet nebulizer in premature infants with bronchopulmonary dysplasia
Authors: Zhou Jian-Fu , Zhang Yi-Bing , Zhang Zhi-Wei
Published: November 2023

Background

This study aimed to compare the efficacy of budesonide inhalation suspension administered via a vibrating mesh nebulizer vs. a jet nebulizer in the treatment of premature infants with bronchopulmonary dysplasia (BPD) undergoing high-frequency oscillatory ventilation (HFOV).

Methods

Between July 2020 and July 2022, we retrospectively analyzed the medical records of 36 preterm infants diagnosed with BPD who underwent HFOV. Based on the nebulizer type used, infants were categorized into the vibrating mesh nebulizer group (VMN group) or the jet nebulizer group (JN group). Post-nebulization outcomes, such as the duration of mechanical ventilation, length of stay in the neonatal intensive care unit (NICU), ventilator-associated parameters, and arterial blood gas metrics, were compared between the two groups. Treatment-associated complications were also documented.

Results

No significant differences were noted between the VMN and JN groups in terms of mechanical ventilation duration (p = 0.519), NICU length of stay (p = 0.112), ventilator-associated parameters, or complications (p = 0.700). However, after 2 weeks of treatment, the oxygenation index (p = 0.012) and arterial partial pressure of carbon dioxide (p = 0.006) were more favorable in the VMN group compared to the JN group.

Conclusion

Among premature infants with BPD on HFOV, for administration of budesonide inhalation suspension resulted in an improved oxygenation index and reduced arterial partial pressure of carbon dioxide when compared to a jet nebulizer, indicating superior therapeutic efficacy.
Effects of high-intensity interval training program on pituartry function in basketball players: a randomized controlled trial
Authors: Soslu Recep , Uysal Abdullah , Devrilmez Meltem , Can Çuvalcıoğlu İsmail , Doğan Ali Ahmet , Karaburgu Sülbiye , Taş Murat
Published: November 2023

The aim of the study was to determine how the short high-interval training program affects cortisol levels in basketball players. A total of 27 male basketball players volunteered for the study and were randomly assigned to one of two groups: Control Group (CG) (n = 13, mean age; 20,56 ± 1,45 years, mean height; 184,53 ± 6,65 cm) and Experimental Group (EG) (n = 14, mean age; 20,71 ± 2,12 years, mean height; 86,51 ± 8,21 cm). The experimental group received a 7-week interval training program. Blood samples were taken at the beginning and end of the study. Cortisol, Adrenocorticotropic Hormone, Triiodothyronine, Tetraiodothyronine, Parathyroid Hormone, Thyroid Stimulating Hormone, Insulin, and Glucose levels were measured of the EG and CG. To test the differences between groups and compare the effects of pre and post-intervention, a two-way ANOVA for repeated measures was used. Consequently, the post-test levels of TSH, PTH, and ACTH in the exercise group showed a significant difference when compared to the pre-test values (p = 0.000). Moreover, the post-test levels of Glucose, Cholesterol, Triglyceride, HDL, and Mg in the exercise group showed statistical significance when compared to the pre-test values (p = 0.000). Significant differences were seen in the post-test PTH and ACTH levels of the control group when compared to the pre-test values (p = 0.000). Furthermore, the exercise group showed significant differences in post-test values for HDL and Cholesterol compared to the pre-test (p = 0.000). In addition, when comparing the post-test values and pre-test values of both the exercise group and the control group, it was found that all parameters, with the exception of Ca, exhibited substantial differences in favor of the exercise group. It may be claimed that the implementation of interval training has favorable outcomes on pituitary function parameters. Additionally, the regulation of energy consumption during exercise is favourably influenced, along with the reduction of physiological stress resulting from prolonged exercise.
Geographical and life-history traits associated with low and high species richness across angiosperm families
Authors: Ferrer Miriam Monserrat , Vásquez-Cruz Marilyn , Hernández-Hernández Tania , Good Sara V.
Published: November 2023

Introduction

The phenomenal expansion of angiosperms has prompted many investigations into the factors driving their diversification, but there remain significant gaps in our understanding of flowering plant species diversity.

Methods

Using the crown age of families from five studies, we used a maximum likelihood approach to classify families as having poor, predicted or high species richness (SR) using strict consensus criteria. Using these categories, we looked for associations between family SR and i) the presence of an inferred familial ancestral polyploidization event, ii) 23 life history and floral traits compiled from previously published datasets and papers, and iii) sexual system (dioecy) or genetically determined self-incompatibility (SI) mating system using an updated version of our own database and iv) geographic distribution using a new database describing the global distribution of plant species/families across realms and biomes and inferred range.

Results

We find that more than a third of angiosperm families (65%) had predicted SR, a large proportion (30.2%) were species poor, while few (4.8%) had high SR. Families with poor SR were less likely to have undergone an ancestral polyploidization event, exhibited deficits in diverse traits, and were more likely to have unknown breeding systems and to be found in only one or few biomes and realms, especially the Afrotropics or Australasia. On the other hand, families with high SR were more likely to have animal mediated pollination or dispersal, are enriched for epiphytes and taxa with an annual life history, and were more likely to harbour sporophytic SI systems. Mapping the global distribution of georeferenced taxa by their family DR, we find evidence of regions dominated by taxa from lineages with high vs low SR.

Discussion

These results are discussed within the context of the literature describing “depauperons” and the factors contributing to low and high biodiversity in angiosperm clades.
Anxiety and depression in geriatric hemodialysis patients: factors that influence the border of diseases
Authors: Elezi Brunilda , Abazaj Erjona , Zappacosta Bruno , Hoxha Malvina
Published: November 2023

Introduction

The two main psychological issues that people with end-stage renal disease (ESRD) experience are depression and anxiety. We conducted this study to determine both the prevalence of depression and anxiety, and the factors associated with them, among hemodialysis patients.

Methods

Patients aged 18 years or older, who had received hemodialysis in a hemodialysis center in Elbasan, for at least 3 months were included in this study. Beck Anxiety Inventory and Beck Depression Inventory Instruments were used to assess hemodialysis patients levels of depression and anxiety.

Results

Overall, 107 hemodialysis patients (men 65.4%) with a mean age of 57 ± 8.9 years were enrolled in the study. The prevalence of anxiety and depression resulted to be 85.98, and 84.11%, respectively. We found a significant difference in depression and anxiety scores in patients age groups of 61–70 years old (OR = 1.8; 95% CI [0.7–3.7]; p = 0.041), in non-smoking patients (OR 3.4; 95% CI [1.09–8.2]; p = 0.04), in diabetic patients (OR 3.4; 95% CI [1.09–8.2]; p = 0.04), and in patients with a time in dialysis of 6–10 years and >11 years, respectively, (OR 3.4; 95% [1.5–9.0]; p = 0.01), (OR1.3; 95% CI [0.4–3.6]; p = 0.04).

Conclusion

Our study shows that the prevalence of mental disorders (depression and anxiety) is high among patients with ESRD on maintenance hemodialysis. We recommend a routine screening and referral to psychological health specialists to evaluate the mental health disorders among hemodialysis patients with the primary aim of improving their quality of life.
Tailoring the continuum of care for substance use problems to persons with an Islamic migration background: a co-creative case study
Authors: Pouille Aline , Bouachiba Arafat , De Ruysscher Clara , Vander Laenen Freya , Vanderplasschen Wouter
Published: November 2023

Introduction

Structural inequity and stigma impose barriers toward substance use prevention and recovery support for persons with an Islamic migration background in non-Islamic majority countries. Similar issues of differential power often keep them silenced in research. Therefore, we explore the continuum of care for substance use problems regarding persons with an Islamic migration background.

Methods

We draw from a co-creative case study with Arafat, whose lived and professional experiences as a Muslim with a history of problem substance working in the field, were blended with academic literature through the process of ‘plugging in’.

Results

We discuss (1) culturally competent and selective substance use prevention, (2) facilitating access to adequate support services, (3) culturally competent substance use treatment and (4) supporting long-term recovery for persons with an Islamic background from a combined academic, professional and lived experiences perspective.

Discussion

We discuss the need for tailored interventions that are able to overcome structural inequities and address ethnocultural sensitivities, needs and strengths. Intermediary community organizations, cultural competence of treatment and recovery-oriented systems of care may bridge the gaps between what is needed and what is available. However, it is important to be conscious that hands-on solutions at the personal level do not absolve the responsibility of searching for systemic solutions. Furthermore, awareness of the fine line between cultural competence and culturalization, taking into account the danger of essentializing, othering and overlooking other intersectional traits of diversity, is needed.
Sex differences evident in elevated anxiety symptoms in multiple sclerosis, inflammatory bowel disease, and rheumatoid arthritis
Authors: Joyees Jerlin , Marrie Ruth Ann , Bernstein Charles N. , Bolton James M. , Fisk John D. , Graff Lesley A. , Hitchon Carol , Patten Scott B. , Kowalec Kaarina ,   for the CIHR team in defining the burden and managing the effects of psychiatric comorbidity in chronic immunoinflammatory disease
Published: November 2023

Introduction

Immune-mediated inflammatory diseases (IMID), such as multiple sclerosis (MS), inflammatory bowel disease (IBD) or rheumatoid arthritis (RA) have high rates of elevated anxiety symptoms. This can may worsen functioning and increase IMID disease burden. The rate of and factors associated with elevated anxiety symptoms may differ between males and females, which, in turn can affect diagnosis and disease management. We evaluated whether the frequency and factors associated with comorbid elevated anxiety symptoms in those with an IMID differed by sex.

Methods

Participants with an IMID (MS, IBD or RA) completed two anxiety measures (HADS, GAD-7). We used logistic regression to investigate whether sex differences exist in the presence of comorbid elevated anxiety symptoms or in the endorsement of individual anxiety items in those with an IMID.

Results

Of 656 participants, females with an IMID were more likely to have elevated anxiety symptoms compared to males (adjusted odds ratio [aOR] 2.05; 95%CI: 1.2, 3.6). Younger age, higher depressive symptoms and income were also associated with elevated anxiety symptoms in IMID. Lower income in males with an IMID, but not females, was associated with elevated anxiety symptoms (aOR: 4.8; 95%CI: 1.5, 15.6). No other factors demonstrated a sex difference. Males had nearly twice the odds of endorsing restlessness on the GAD-7 (OR = 1.8, 95%CI: 1.07, 3.15) compared to females.

Discussion

We found evidence for sex differences in the factors associated with experiencing elevated anxiety symptoms in those with an IMID. These findings could be helpful to sensitize clinicians to monitor for comorbid anxiety symptoms in males with an IMID.
The effect of the COVID-19 pandemic on the provision of outpatient clinic services in East Jerusalem hospitals: patients’ perspectives
Authors: Ahmead Muna , Daghlas Firas
Published: November 2023

Background

Due to the decreased availability, accessibility, and quality of services, the COVID-19 pandemic has an impact on the healthcare system. In the wake of the COVID-19 pandemic, patients’ perceptions of healthcare have changed, and out-patient visits to clinics have decreased. As part of the COVID-19 outbreak in East Jerusalem, this study aims to assess how patients perceive the way that outpatient clinic services were delivered before and during COVID-19 outbreak.

Methodology

Convenience sampling and self-reported questionnaires were used in a cross-sectional study. Three hundred people from three significant outpatient clinic hospitals in East Jerusalem-Al-Makassed Hospital, Augusta Victoria Hospital, and Sant-Joseph Hospital- made up the sample. Multivariate tests, frequencies, and percentages were used in the statistical analysis.

Results

The results showed that the most of the participants (98.6%) had negative opinion when the current situation is compared with before the COVID-19 period in terms of accessibility, availability of resources, quality of care, attitudes and patient’s preference. Finally, multivariate analysis indicated a significant relationship between participant opinion and education level and participants with educational levels of 12 study years or less had more positive opinions of the delivery of the healthcare system during the COVID-19 outbreak period than the group with more than 12 study years. Also, the multivariate analysis revealed a significant `relationship between participant opinion and the duration of the illness as those with years of illness and less had more negative opinion toward the delivery of the healthcare system than those with more than 3 years of illness.

Conclusion

This study found that when the current situation during the COVID-19 outbreak is compared to before the COVID-19 period in terms of accessibility, availability of resources, quality of care, attitudes, and patient preferences, the majority of the participants with chronic diseases or cancer had a negative opinion. Policymakers and health managers should enhance patient preferences and attitudes during the COVID-19 pandemic and other pandemics by increasing accessibility, availability of health resources, and the quality of healthcare.
Invoking and identifying task-oriented interlocutor confusion in human-robot interaction
Authors: Li Na , Ross Robert
Published: November 2023

Successful conversational interaction with a social robot requires not only an assessment of a user’s contribution to an interaction, but also awareness of their emotional and attitudinal states as the interaction unfolds. To this end, our research aims to systematically trigger, but then interpret human behaviors to track different states of potential user confusion in interaction so that systems can be primed to adjust their policies in light of users entering confusion states. In this paper, we present a detailed human-robot interaction study to prompt, investigate, and eventually detect confusion states in users. The study itself employs a Wizard-of-Oz (WoZ) style design with a Pepper robot to prompt confusion states for task-oriented dialogues in a well-defined manner. The data collected from 81 participants includes audio and visual data, from both the robot’s perspective and the environment, as well as participant survey data. From these data, we evaluated the correlations of induced confusion conditions with multimodal data, including eye gaze estimation, head pose estimation, facial emotion detection, silence duration time, and user speech analysis—including emotion and pitch analysis. Analysis shows significant differences of participants’ behaviors in states of confusion based on these signals, as well as a strong correlation between confusion conditions and participants own self-reported confusion scores. The paper establishes strong correlations between confusion levels and these observable features, and lays the ground or a more complete social and affect oriented strategy for task-oriented human-robot interaction. The contributions of this paper include the methodology applied, dataset, and our systematic analysis.
Does the Design of Buildings Affect Our Minds?
Authors: Bower Isabella S. , Hill Aron T. , Tucker Richard , Enticott Peter G.
Published: November 2023

Do buildings affect how we feel and, if so, how can we tell? Currently, we can only ask people, which relies on them being able to accurately identify their emotions. As our emotions influence how we think, behave, and work, it is important to understand whether the places we spend time in, like our homes, offices, schools, and hospitals, affect us. We ran an experiment with more than 60 healthy adults. Participants sat in a virtual reality room, which we made larger or smaller, or we colored the walls. To understand if the size or color of the room affected their brains and bodies, we used sensors on the skin and asked participants to tell us about their emotions. We found that room size and color affected brain activity associated with concentration and emotion. This suggests that the buildings we spend time in impacts the ways we interact with the world.
Insects as Clues: What Can Butterflies Tell Us About Environmental Health?
Authors: Lourenço Giselle Martins , Rodrigues Domingos Jesus , Sobral-Souza Thadeu
Published: November 2023

Butterflies can quickly inform us about the health of the environment—they are like perfect clues used by detectives when solving mysteries! Why? First, because butterflies can be found practically everywhere. Second, because butterfly communities are sensitive to very small changes in the environment. By investigating the butterflies in a certain location, researchers can learn about the current health of the environment and see evidence of things humans may have done in the past to impact the area. Cutting down forests, for example, changes to the types of butterfly species living in an area and can lead to the extinction of some species. In this way, studying butterflies helps us understand the effect of human impacts on the environment. Based on what they learn from butterflies, researchers can propose conservation actions to protect certain species—and the whole environment. So, the next time you look at a butterfly, maybe it will make you consider the health of the environment around you.
Post-activation performance enhancement does not occur following a large hand-paddles and parachute-resisted warm-up routine in collegiate swimmers
Authors: Bufalo Santiago Soares , Fontanetti Gabriel , Barreto Renan Vieira , Benazzi Gabriel Rocha , Junior Rubens Correa , Marangoni Victor , Bassan Natália de Menezes , Denadai Benedito Sérgio , Greco Camila Coelho , Vilas-Boas João Paulo , Lima Leonardo Coelho Rabello de
Published: November 2023

Our aim was to investigate if using a warm-up routine that included parachute-resisted sprints with large hand-paddles improves 50 m freestyle performance in trained collegiate swimmers. Twelve swimmers (23.9 ± 2.2 years, 179 ± 7 cm, 77.1 ± 10.6 kg) participated in the study and completed two 50-m freestyle races, each preceded by a different warm-up routine, either control (CON) or experimental (EXP). The warm-up routines consisted of 500 m of swimming at self-selected speed, followed by four 10 s sprints with 1 min rest intervals. During EXP, sprints were performed using large hand-paddles and a swimming parachute, while during CON, sprints were performed freely. Performance and technique were assessed during the 50 m freestyle races. We found no significant differences in 25- and 50 m performance times (CON: 12.6 ± 0.8 vs. EXP: 12.5 ± 0.8 s, ES = 0.125; and CON: 26.8 ± 1.6 vs. EXP: 26.7 ± 1.7 s, ES = 0.06, respectively) between the two conditions. Mean stroke length (CON: 2.04 ± 0.21 vs. EXP: 2.02 ± 0.22 m·cycle−1, ES = 0.09), stroke frequency (CON: 55.4 ± 5.3 vs. EXP: 56.3 ± 5.2 cycles s−1, ES = 0.17), and propulsive time (CON: 0.62 ± 0.07 vs. EXP: 0.61 ± 0.06 s, ES = 0.15) were also not different between conditions. It is possible that the CON warm-up routine induced the priming effects that lead to PAPE, or that the EXP warm-up routine primed the athletes further but also induced greater fatigue, resulting in no significant effects on swimming performance. Our findings suggest that parachute-resisted sprints with hand-paddles during warm-up do not enhance 50 m freestyle swimming performance in trained collegiate swimmers. Coaches and practitioners should consider exploring different warm-up protocols to identify what works best for their athletes.
Family Caregivers Employed by Home Care Agencies: Lessons Learned From Switzerland and the United States
Authors: Bischofberger Iren , Vetter Mary Jo
Published: November 2023

Background: Increasing demands for home care staff has been triggered in the past decades by shorter hospital length of stay, and a shift of responsibility for complex care regimens to private households. Therefore, an innovative model to employ family caregivers in home care agencies is expanding in Switzerland and the United States. This policy brief aims to identify core characteristics of the model and analyze its potential benefits and challenges.

Evidence: The model is expanding based on legal ground but without the requisite scientific evidence. After an initial patient assessment by a registered nurse, and assigned hands-on tasks to family caregivers, the salary is derived from payer reimbursement.

Policy Options and Recommendations: Standards need to be in place to determine the family caregivers qualification that are specific to the client situation of all age groups. Supervision of quality of care, labor law, and blurred roles of biographical relationships remains at the responsibility of the home care agency.

Conclusion: Further research for the data-driven exploration of the model is needed to inform the many stakeholders involved.
Coevaluación y aprendizajes en los estudiantes de la Institución Educativa Zegel Ipae, Lima 2023. Valoración de una experiencia
Authors: Chocobar-Reyes Emilio José
Published: November 2023

La investigación tuvo el objetivo de identificar los efectos de implementar la coevaluación entre estudiantes de la institución educativa Zegel Ipae como herramienta de la evaluación, 2023. La metodología fue cuantitativa, diseño cuasiexperimental y explicativa.  La unidad de análisis fueron dos grupos de estudiantes de cursos diferentes donde participaron un total de 41 distribuidos en cada grupo: G1 (27) y G2 (14). Al ser cuasiexperimental se implementó un instrumento de coevaluación innovador en ambos cursos y luego se aplicó una encuesta para levantar información. A diferencia de otros cursos en los cuales no se aplica la coevaluación, los resultados respecto de las actividades de estudio determinaron que más del 85% de estudiantes consideraron que la coevaluación logró una mejor distribución de las tareas, aumentó la participación y asistencia a las reuniones programadas y se buscó mayor y mejor información elevando la calidad de las tareas y/o exámenes. Respecto de las dificultades más del 74% señalaron que, a pesar de ser la primera vez que aplican la coevaluación, lograron superar el temor inicial logrando minimizar los problemas de falta de participación, asistencia a las reuniones e incumplimiento de tareas.  Respecto de las satisfacciones más del 71% señalaron que trabajaron mejor, profundizaron más en los temas académicos, aumentaron su responsabilidad por presión de sus propios compañeros, tomaron mejores decisiones y aprendieron a aplicar el control y seguimiento entre ellos. La investigación demostró que el instrumento de coevaluación implementado generó grandes beneficios y mejoró el proceso de enseñanza y aprendizaje en los estudiantes.
Innovación pedagógica en el proceso de enseñanza-aprendizaje de matemáticas para estudiantes de Educación General Básica considerando las Tecnologías de la Información y la Comunicación
Authors: Potes-Duque Freddy Bayron , Jiménez-Contreras Johnny José
Published: November 2023

Las Matemáticas son consideradas como una ciencia exacta en las competencias del currículo de Educación Básica, actualmente con estudiantes nativos digitales en las aulas. Para una acertada aplicación de Tecnologías de Información y Comunicación en los procesos de enseñanza-aprendizaje de las matemáticas, es necesaria una conexión con los procesos experienciales y las innovaciones educativas. El objetivo de este artículo fue implementar la estrategia de innovación pedagógica en la enseñanza-aprendizaje basada en TIC en el campo de las matemáticas de educación básica y evaluar sus efectos. Se utilizó un enfoque transversal mixto, un análisis sistemático de la literatura correlacionada de la base de datos Scopus y el análisis bibliométrico de la literatura utilizando criterios de exclusión de palabras clave en la herramienta VOSviewer. Se identificaron las principales estrategias pedagógicas de las innovaciones educativas existentes que aplican las TIC específicas de las matemáticas. Luego, en el desarrollo de un plan de lección en un curso de 10mo para la Educación Básica de matemáticas en una institución educativa, se implementó la estrategia de innovación educativa con una muestra de 22 estudiantes, entre los cuales los estudiantes reconocieron y aplicaron un índice de percepción de 95,45% en el aprendizaje y calificaron a las herramientas TIC aplicadas con el 100% de usabilidad, utilidad y aplicabilidad, además, se demostró una tasa de satisfacción de aprendizaje del 100%. Al evaluar el proceso se evidenció que 95,46% de estudiantes mejoran el rendimiento y desempeño alcanzando los objetivos académicos sustentados en integración de modelos y estrategias de aprendizaje activo.
Comunicación, educación y desarrollo: el reto de la pandemia
Authors: Molina-Molina Ibeth Johana , Suárez-Molina Veronica Johana , Moreno-Pérez Elssy Yamile , Durán-Sánchez Carlos Alberto
Published: November 2023

Este artículo presenta los resultados de una investigación realizada entre 2021 y 2022, cuyo propósito fue el reconocimiento de las transformaciones, aprendizajes y retos más significativos que dejó la pandemia en las prácticas comunico-educativas docentes, en 19 instituciones educativas rurales y urbanas en Colombia en el contexto de la pandemia ocasionada por la COVID 19. El estudio se realiza a partir del análisis de las narrativas de docentes y estudiantes; por ello, visibiliza las experiencias docentes, el uso de las Tecnologías de la Información y la Comunicación, para la enseñanza y su relevancia en los contextos sociales en los que tuvieron lugar. Metodológicamente, se ubica en el enfoque cualitativo y acude a instrumentos propios del método biográfico como las historias de vida y las entrevistas. Finalmente, la fortaleza de la experiencia narrativa precisó que las desigualdades tecnológicas suscitaron prácticas formales e informales, con formas comunicativas que afianzaron el tejido social y ayudaron superar dificultades.
Designing Inorganic–Organic Dual-Acid Deep Eutectic Solvents for Synergistically Enhanced Extractive and Oxidative Desulfurization
Authors: Zhu Dongao , Xu Lixian , Zhang Beibei , Zhu Linhua , He Jing , Li Hongping , Li Huaming , Jiang Wei
Published: November 2023

Acidic deep eutectic solvents (DESs) have been considered desirable extractants and catalysts for desulfurization. However, their hydrogen bond donors (HBDs) are usually sole organic acids, which are not conducive to efficient green catalysis. Herein, a novel inorganic–organic dual-acid DES (DADES) was reported for efficient extractive and oxidative desulfurization. Benefiting from the physical interaction among the three components in a DADES, a transparent homogeneous liquid can be obtained even though inorganic acid (boric acid, BA) and organic acid (acetic acid, AA) can be immiscible. Furthermore, the dual-acid HBD can increase the acidity of the DADES and reduce its viscosity, accelerating its mass transfer efficiency and enhancing its catalytic activity. With 1-butyl-3-methylimidazolium chloride ([Bmim]Cl) as the hydrogen bond acceptor, [Bmim]Cl/BA/0.3AA effectively activated hydrogen peroxide and achieved sulfur removal of 96.6% at 40 °C. Furthermore, the universality of the synergistic effect in various DADESs was confirmed by the modulation of the types of organic acids. This study not only motivates the construction of more intriguing novel DESs based on the DADES concept but also highlights their potential in clean fuel production.
Parameter Optimization of Ultrasonic–Microwave Synergistic Extraction of Taxanes from Taxus cuspidata Needles
Authors: Zhao Zirui , Zhang Yajing , Li Wenlong , Tang Yuanhu , Wang Shujie
Published: November 2023

Taxanes are the best-known compounds in Taxus cuspidata owing to their strong anticancer effects. However, the traditional taxanes extraction method is the solid–liquid extraction method, which is limited by a large energy consumption and low yield. Therefore, it is urgent to find an efficient method for taxanes extraction. The ultrasonic microwave synergistic extraction (UME) method integrates the cavitation effect of ultrasound and the intensifying heat transfer (ionic conduction and dipole rotation of molecules) effect of microwave to accelerate the release of intracellular compounds and is used in active ingredient extractions. This study aimed to evaluate the performance of UME in extracting taxanes from T. cuspidata needles (dichloromethane-ethanol as extractant). A single-factor experiment, Plackett–Burman design, and the response surface method showed that the optimal UME parameters for taxanes extraction were an ultrasonic power of 300 W, a microwave power of 215 W, and 130 sieve meshes. Under these conditions, the taxanes yield was 570.32 μg/g, which increased by 13.41% and 41.63% compared with the ultrasound (US) and microwave (MW) treatments, respectively. The reasons for the differences in the taxanes yield were revealed by comparing the physicochemical properties of T. cuspidata residues after the UME, US, and MW treatments. The cell structures were significantly damaged after the UME treatment, and numerous tiny holes were observed on the surface. The absorption peaks of cellulose, hemicellulose, and lignin increased significantly in intensity, and the lowest peak temperature (307.40 °C), with a melting enthalpy of −5.19 J/g, was found after the UME treatment compared with the US and MW treatments. These results demonstrate that UME is an effective method (570.32 μg/g) to extract taxanes from T. cuspidata needles by destroying cellular structures.
Multistage Self-Assembled Nanomaterials for Cancer Immunotherapy
Authors: Guo Lamei , Yang Jinjun , Wang Hao , Yi Yu
Published: November 2023

Advances in nanotechnology have brought innovations to cancer therapy. Nanoparticle-based anticancer drugs have achieved great success from bench to bedside. However, insufficient therapy efficacy due to various physiological barriers in the body remains a key challenge. To overcome these biological barriers and improve the therapeutic efficacy of cancers, multistage self-assembled nanomaterials with advantages of stimuli-responsiveness, programmable delivery, and immune modulations provide great opportunities. In this review, we describe the typical biological barriers for nanomedicines, discuss the recent achievements of multistage self-assembled nanomaterials for stimuli-responsive drug delivery, highlighting the programmable delivery nanomaterials, in situ transformable self-assembled nanomaterials, and immune-reprogramming nanomaterials. Ultimately, we perspective the future opportunities and challenges of multistage self-assembled nanomaterials for cancer immunotherapy.
Traditional Uses, Pharmacological Activities, and Phytochemical Analysis of Diospyros mespiliformis Hochst. ex. A. DC (Ebenaceae): A Review
Authors: Ramadwa Thanyani Emelton , Meddows-Taylor Stephen
Published: November 2023

Diospyros mespiliformis Hochst. ex. A. DC is widely distributed throughout Africa and around the world. It is utilized ethnobotanically to treat fevers, wounds, malaria, diabetes mellitus, and other diseases. This review aims to provide an exhaustive overview of the traditional uses, pharmacology, and phytochemical analysis of D. mespiliformis, with the objective of identifying its therapeutic potential for further research. Scientific resources, including Google Scholar, Science Direct, Web of Science, Pub Med, and Scopus, were used to find pertinent data on D. mespiliformis. Secondary metabolites tentatively identified from this species were primarily terpenoids, naphthoquinones, phenolics, and coumarins. D. mespiliformis has been reported to demonstrate pharmacological activities, including antimicrobial, antiproliferative, antiparasitic, antioxidant, anti-inflammatory, antiviral, anti-hypersensitivity, and antidiabetic properties. The phytochemicals and extracts from D. mespiliformis have been reported to have some pharmacological effects in in vivo studies and were not toxic to the animal models that were utilized. The D. mespiliformis information reported in this review provides researchers with a comprehensive summary of the current research status of this medicinal plant and a guide for further investigation.
Cutaneous Leishmaniasis Prevalence and Clinical Overview: A Single Center Study from Saudi Arabia, Eastern Region, Al-Ahsa
Authors: Al-Dhafiri Mahdi , Alhajri Abdulmohsen , Alwayel Zahraa Ali , Alturaiki Jasmine Ahmed , Bu Izran Shaima Ali , Alhammad Fatimah Ahmed , Aljumaiah Ryhana Mohammed
Published: November 2023

Cutaneous leishmaniasis (CL) is a vector-borne parasitic disease that is transmitted via the bites of infected female sandflies. CL has been endemic in several countries worldwide for many decades, and numerous cases have been reported in Saudi Arabia, particularly across six regions; one of which is AL-Ahsa. Our research aimed to evaluate the epidemiological situation of CL among the patients in Al-Ahsa, Eastern region, Kingdom of Saudi Arabia, during the period from 2017 to 2023. The data were collected from the patients’ registries and included 245 patients who were diagnosed with CL in Al-Ahsa, Saudi Arabia. Fewer than half of the cases (47.8%) were Saudi patients, with a significant number of them being males (84.5%). Over half of the cases (52.7%) were aged between 21 and 40 years, and about three-quarters (74.7%) of the cases resided in rural areas. Regarding the nature of the lesions, 38.4% of the cases had one lesion, which was mainly distributed on a lower extremity (62.0%) or an upper extremity (52.2%). A high percentage of the lesions (75.2%) were wet lesions and caused by L. major. Concerning risk factors, a greater number of patients (71.4%) had been in rural areas within the last three months. Additionally, more than half of the cases (54.3%) had close contact with rodents, followed by birds (28.2%), sheep (22.0%), dogs (16.3%), and other animals (1.2%). The results showed a low number of reported CL cases in 2020 and 2021, followed by a surge in 2022 and 2023. The study shows that cutaneous leishmaniasis is still a public health problem in Al-Ahsa and is primarily associated with rural areas.
PSYCHOLOGICAL EXPERT EXAMINATION OF INCLUSIVE EDUCATIONAL ENVIRONMENT: THEORETICAL ANALYSIS
Authors: Bunjak N.
Published: November 2023

The results of the analysis of psychological problem of the education system readiness for the inclusion process implementation are considered in this paper.

Within the formation of the inclusive education environment, the author is particularly sympathetic toward the understanding of inclusive education as a specially organized interaction of teachers and individuals with special needs and normative development level.

Inclusive education is a systematic process of well-organized interaction between all participants of the educational process.

The theoretical approaches to the problems of education of individuals having special educational needs, based on equality are summarized in this paper. It is concerned with the possibility of implementation of the right to education in typical educational institution, opened for education of individuals with physical, intellectual, social, emotional, linguistic or other features.

The author emphasizes that the primary problem in creating the inclusive educational environment at present is the professional training of teachers focused on the  work with individuals who have special educational needs.
PECULIARITIES OF PROFESSIONAL-PSYCHOLOGICAL TRAINING OF LAW ENFORCEMENT EMPLOYEES
Authors: Goncharova N.
Published: November 2023

The article focuses on the peculiarities of the professional activities of law enforcement officers, the definition of components that affect the level of psychological readiness of professionals (strict legal regulation of professional conduct, authoritative and mandatory nature of professional powers, the extreme nature of law enforcement, procedural independence).

Qualitative characteristics of law enforcement officers' activity are analyzed: normativeness, organization, preparedness and efficiency.

The components of professional and psychological training of law enforcement officers for activities are presented: professional and psychological orientation and sensitivity, knowledge and skillful use of psychological tools and techniques, developed professional observation and memory, psychological stability.

The article notes that professional and psychological training promotes the development of professional skills of law enforcement officers, ie readiness to act professionally in any conditions. It is aimed at the formation and development of psychological characteristics of the individual that meet the specific and important psychological characteristics of service activities and are one of the necessary prerequisites for its implementation.
ANALISIS AKUNTABILITAS DAN TRANSPARANSI DALAM PENGELOLAAN KEUANGAN MASJID AL-AHSANI KEC. SUNGGAL KAB.DELI SERDANG
Authors: Adfi Muhammad Kholid , Nurwani Nurwani , Nasution Yenni Samri Juliati
Published: November 2023

The purpose of this study is to improve the financial accountability and transparency of Al-Ahsani Mosque. This is an example of quantitative research. Quantitative research. Documentation, field observation, observation, and interviews were used to obtain data with two informants related to Al-Ahsani Mosque, namely the mosque chairman and the mosque treasurer. The investigation method applied was a case study. The results showed a positive attitude towards the responsibility given to mosque administrators in carrying out non-profit (mosque) financial policies. Transparency in mosque financial management is still not fully implemented in transparency in financial management reporting. It's just that the transparency implemented by the Mosque is in the form of announcing the records of the mosque's financial statements every Friday in person.

Key words: Financial Reporting, Accountability, Transparency
The Specific Characteristics of the Creativity of Alexander Chekmenev in the Concept of the Development of Social Documentary as a Significant Part of Contemporary Ukrainian Art Photography
Authors: Safronova Anna , Mihaescu Camil , Safronova Olena , Safronov Valeriy
Published: November 2023

Social documentary photography is one of the key genres that Ukrainian artists use for creating a series of works presented in the form of a photo book or as an independent project. Among the most prominent representatives of this direction, Alexander Chekmenev and the members of Kharkov School of Photography (Boris Mikhailov, Evgeny Pavlov, Mikhail Pedan, etc.) should be singled out. It is notable that despite the fact that their works have common issues, the similar choice of the method and general stylistics, there are a number of significant differences. With the transfer of individual facial features, Aleksander Chekmenov seeks to reveal the psychology of the person being portrayed and elevate a person in the eyes of others, while representatives of the Kharkov school of photography use sharp, satirical language with the active inclusion of various manipulations of the image. On the basis of the art history analysis of a number of well – known projects by Alexander Chekmenev, certain regularities in the strategy of creating a social documentary project in his works have been identified.
Evaluasi Kepatuhan POS Pembelian Perusahaan Tekstil dalam Persiapan Sertifikasi ISO 9001:2015
Authors: Wehartaty Tineke Wehartaty , Handoko Jesica , Yudhanti Ceicilia Bintang Hari , Nugraheni Bernadetta Diana
Published: November 2023

The research object is PT Jimas, a textile waste processing manufacturing company, where PT Jimas is in preparation for ISO 9001:2015 certification. During the COVID 19 pandemic, PT Jimas remained fully operational in accordance with government regulations and underwent changes in procedures and documents in its purchasing cycle. One of the things assessed in ISO 9001: 2015 certification is compliance with the implementation of existing SOPs. Purchasing cycle SOP compliance audit, manufacturing companies can check the conformity of the management system with the audit criteria, namely the required material standards, the company's purchasing management system, supplier requirements and others. This research is expected to contribute to PT Jimas, especially in measuring compliance in the implementation of the purchase cycle SOP, by designing a Purchase Cycle Compliance checklist, starting from the initial supplier selection procedure to paying purchase debts.The research was conducted using descriptive qualitative methods, namely interviews and checking related documents. The results of this study are that PT Jimas is quite compliant in carrying out procedures and using purchasing documents, but in the context of adjusting to changes related to the COVID 19 pandemic, PT Jimas requires socialization of the latest SOP purchasing cycle. The socialization of the implementation of the SOP purchasing cycle is expected to increase PT Jimas' compliance and be useful in preparation for obtaining ISO 9001: 2015 certification.