bluuebunny/crossref_metadata_2025 huggingface dataset:
Organizational factors: a case study of the cost-benefit of implementing control measures in precast structure constructions
Authors: Almeida Filho Roberto Revoredo de , Cruz Felipe Mendes da
Published: January 2022

O presente artigo tem como objetivo demonstrar a implantação de sistemas de inspeção sistemáticas em obras como estratégia de gestão de riscos da empresa na identificação de desvios, bem como propor soluções organizacionais de baixo custo de implantação. A metodologia foi dividida em 5 partes. A primeira etapa consistiu na revisão da literatura, cujo objetivo era encontrar documentos e produções científicas relevantes ao tema discutido neste artigo. Em seguida, foi elaborado um check-list fundamentado na Norma Regulamentadora 18 (NR 18) - Condições e Meio Ambiente de Trabalho na Indústria da Construção e outras. Com a parte documental (check-list) finalizada, foram realizados os procedimentos de campo na obra. Após finalizada a obra e os relatórios entregues, foi realizado levantamento das não conformidades encontradas para que os dados fossem analisados. Por fim, foi realizada a análise de custo-benefício das medidas de controle implementadas. As irregularidades que mais ocorreram durante a execução do projeto foram: pontas verticais de vergalhões desprotegidas; funcionários sem usar o EPI e número insuficiente de instalações sanitárias. Os indicadores de segurança mostraram que os ciclos onde eram realizadas simultaneamente atividades de Estrutura, Alvenaria e Vedação Interna, Instalações Prediais e Acabamento, foram os com maior índice de irregularidades. Por fim, foi verificado que para cada valor unitário investido em medidas de controle de segurança, a proteção com passivos financeiros de multas é 16 vezes maior. Desta forma, todo custo voltado para adequar as condições de trabalho dos colaboradores reflete positivamente para a gestão contábil das obras da construção civil.
Processo de alta hospitalar de pessoas com acidente vascular cerebral: uma revisão narrativa de literatura
Authors: Seeber Fernanda , Peixer Camille , Kanan Lilia Aparecida , Masiero Anelise Viapiana
Published: January 2022

O estudo objetivou a realização de uma revisão narrativa de literatura sobre o processo de alta hospitalar de pessoas com Acidente Vascular Cerebral (AVC). A busca foi realizada nas bases de dados, PubMed e Google Acadêmico, entre os meses de julho e agosto de 2021. Foram utilizados os descritores: “Stroke”, “discharge planning” OR “Transitional Care” AND “Caregivers”. Como critério de inclusão considerou-se publicações que abordaram o tema, publicadas entre os  anos de 2016 a 2021, escritos em idioma português ou inglês e com acesso online. A pré-seleção considerou a leitura de título e resumo das publicaçãoes e classificou ao final 11 para leitura completa. Como principais resultados encontrou-se que o profissional mais envolvido no processo de alta hospitalar de pacientes acometidos por AVC é o enfermeiro (a). Entretanto, parece haver dificuldades no processo de transição do cuidado, principalmente no que se refere a  comunicação e envolvimento dos pacientes e cuidadores na tomada de decisão.  O  planejamento da alta representa estratégia essencial para a transferência do paciente do hospital para casa e pode contribuir para a diminuição: das taxas de reinternação, das complicações, do tempo de internação hospitalar, dos custos de atendimento e de mortalidade. Ainda, destaca-se importância da educação em saúde e do trabalho interprofissional para o cuidado integral de pessoas com AVC.
Multi-objective flower pollination algorithm applied to 5G vehicular networks communication
Authors: Coelho Francisco Jonatas Siqueira , Huampo Eulogio Gutierrez , Lacerda Henrique Figueirôa , Freitas Arthur Doria Meneses de , Silva Filho Abel Guilhermino da
Published: January 2022

The Cellular Vehicle-to-Everything (C-V2X) technology, as a widest version of Vehicular Ad-hoc Network (VANET), aims to interconnect vehicles and any other latest technological infrastructures. In this context, the fifth generation of mobile networks (5G) based on millimeter waves (mmWave) is an excellent alternative for the implementation of vehicular networks, mainly because it is capable of providing high data rates (Gbps) and ultra-low latency, requirements of C-V2X. On the other hand, mmWave signals are highly susceptible to blocking, causing low quality of service (QoS) in VANETs, compromising network functionality and the safety of drivers and pedestrians. Thus, in this work evolutionary computing techniques are applied in the simulation of a 5G vehicular network based on millimeter waves, exploring Media Access Control (MAC) sublayer parameters to optimize packet loss, latency and throughput, in order to optimize inter-vehicular communication. The Multi-objective Flower Pollination Algorithm (MOFPA) was used for this purpose. The results obtained show that the adopted approach can reach results close to the optimal pareto of non-dominated solutions, with a 75% reduction in exploration time in relation to the exhaustive search process. Finally, the performance of the metaheuristics adopted is compared with the non-dominated genetic classification algorithm (NSGA-II) and the multi-objective differential evolutionary algorithm (MODE).
The profile of quality of life and mental health of university students in the healthcare field
Authors: Freitas Pedro Henrique Batista de , Meireles Adriana Lúcia , Barroso Sabrina Martins , Bandeira Marina de Bittencourt , Abreu Mery Natali Silva , David Gabriela Lemes , Paula Waléria de , Cardoso Clareci Silva
Published: January 2022

Objective: to present the profile of quality of life and symptoms of anxiety, depression and stress in university students in the healthcare area. Method: a descriptive study with a quantitative approach to data, carried out with university students in the healthcare field of three Federal Institutions of Higher Education in Minas Gerais. Variables such as sociodemographic, lifestyle, presence of depression symptoms, anxiety and stress, and quality of life (QoL) were measured. The QoL was assessed using the WHOQUOL-bref scale and symptoms of depression, anxiety and stress using the DASS-21 scale. A descriptive data analysis was performed. Results: 321 students participated in the study, mostly female (71.0%). More than 50% of the students had symptoms of depression, anxiety and stress, regardless of the level of severity, while severe/very severe symptoms were present in more than 20% of them, presenting a higher proportion in the nursing course. The psychological domain had the lowest overall QoL score (58.33), and the best was observed in the social relationships domain (66.67). Nursing students had the lowest scores while physical education students had the best scores in most domains. Medical students had the best score in the environment domain (68.75). Conclusion: Suggest the planning of policies and strategies that promote the physical and mental well-being of students, as well as screening and monitoring of most vulnerable ones, as well as those with mental health problems; such strategies can positively impact QoL.
Crescimento inicial da alface hidropônica sob diferentes níveis de salinidade em sistema automatizado com Arduino Uno em função da temperatura e umidade do ar no semiárido
Authors: Rodrigues Leoncio Gonçalves , Meireles Ana Célia Maia , Oliveira Carlos Wagner , Bernardo Livia Soares , Simões Davi Hudson Pereira , Gonçalves Antonio Hyago Mendes
Published: January 2022

O semiárido tem como principais características, baixa precipitação, secas recorrentes, altas temperaturas e baixas umidades do ar. Outro ponto, é que grande parte dos solos possui embasamento cristalino, conferindo qualidade inferior às águas subterrâneas. Nesse sentido, a irrigação, nem sempre é viável, por consequência dos recursos hídricos escassos. A hidroponia, no entanto, independe do solo e requer pouca água, às culturas cultivadas em hidroponia são mais tolerantes à salinidade, permitindo o uso de águas mais salinas. Diante do exposto, o objetivo desta pesquisa foi verificar  o crescimento inicial da alface Crespa cv. Moana  sob cultivo hidropônico no semiárido sob diferentes níveis de salinidade em um sistema automatizado com Arduino Uno, onde o intervalo de aplicação da solução opera em função da temperatura e umidade do ar. Para tanto, foram utilizados os níveis de salinidade 1,5, 2,0, 2,5, 3,0 e 3,5 dS m-1, em  delineamento de blocos ao acaso com esquema fatorial de 5 x 5 no sistema  do tipo Net Film Technique.  Verificou-se que a automação em detrimento da temperatura e umidade promoveu uma maior economia de energia, a alface tem melhor desenvolvimento ao nível de 1,5 dS m-1. Portanto, o sistema de automação com Arduino é operacional além de permitir a associação de sensores, e que a alface cv. Moana para as condições do experimento não apresenta desenvolvimentismo inicial satisfatório acima de 2,0 dS m-1 devido aos efeitos deletérios da salinidade.
Perception of public school students about animal welfare and the occurrence of the topic in education books
Authors: Sitton Heliton Aparecido , Janeck Araujo Matheus , Lovadini Vinicius de Lima , Ramos Gabriela Cortellini Ferreira , Oliveira-Junior Itamar Souza , Marinho Márcia
Published: January 2022

In current time, it is evident the necessity of animal welfare education policies. Animal welfare is defined as the state of an individual attempting to adjust to the environment and education material can encourage dialogue inside schools. We aimed to verify the presence or absence of animal welfare related content in school books and survey the perceptions of the students about the subject, associating with the socioeconomic profile of the school district and with the overall school performance in the SARESP test.  This study was performed between July and November, with seven of the twenty-two public schools in the city of Araçatuba, São Paulo, Brazil. Seven books were collected for analysis from each school, totalizing 49 books, and 430 students answered a survey with 10 questions. The statistical analysis did not show relevant difference between biological gender, age, grade and socioeconomic profile and animal welfare knowledge perception. This study concluded that in most of the analyzed books, animal welfare topics are absent, and that there is no difference between the schools’ socioeconomic profile and animal welfare knowledge perception of the students.
Perfil epidemiológico da infecção por COVID-19 em receptores de transplante renal de um centro do nordeste do Brasil e fatores preditivos de mortalidade
Authors: D’Agnoluzzo Tamye Zimmerman , Alcântara Aline Lima Cunha , Fernandes Paula Frassinetti Castelo Branco Camurça , Girão Evelyne Santana , Sandes Freitas Tainá Veras de , Oliveira Claudia Maria Costa de
Published: January 2022

Objetivos: Investigar a mortalidade por COVID-19 em receptores de transplante renal (TR) e os fatores associados ao maior risco de óbito. Métodos: Os receptores de TR com suspeita de COVID-19 foram monitorados por nefrologistas de março a dezembro de 2020, através de contato telefônico diário, sendo registrados dados clinico-laboratoriais-evolutivos referentes à COVID-19. Uma análise multivariada (regressão logística, forward stepwise) para pesquisa de fatores preditivos de óbito foi realizada. Resultados: Foram confirmados 96 casos de COVID-19 (RT-PCR ou sorologia COVID), sendo 55,2% masculino, idade média 49,1 anos, 90,6% doador falecido e mediana do tempo de TR de 5,2 anos. As comorbidades mais frequentes foram HAS (76%), diabetes (37,5%) e doença cardiovascular (14,6%). A imunossupressão mais utilizada foi tacrolimo/micofenolato (66,7%) e prednisona (69,8%). Em 39,6% dos casos foi necessário internamento, sendo 18,8% em UTI. Em relação aos desfechos, 87,5% ficaram livres da doença e 12,5% foram a óbito. Na análise multivariada, associaram-se à maior chance de óbito: o tempo de transplante superior a 5,7 anos e a idade do receptor superior a 55 anos, enquanto uma menor creatinina basal associou-se à menor chance de mortalidade Conclusão: A mortalidade por COVID-19 em receptores de TR foi superior à da população geral, mas inferior ao descrito em outros centros de transplante. O tempo de transplante e a idade do receptor foram preditivos de óbito nesta população, enquanto uma menor creatinina basal associou-se à menor mortalidade.
Estratégias para a atuação pré-hospitalar diante de pacientes com doença avançada em final de vida e suas famílias: revisão integrativa
Authors: Bammann Luisa Helena Maurell , Cordeiro Franciele Roberta , Corrêa Izadora Martins , Silva Felipe Ferreira da
Published: January 2022

Revisão integrativa de literatura que tem por objetivo identificar as estratégias desenvolvidas internacionalmente para a atuação dos profissionais da atenção pré-hospitalar (APH) diante de pacientes com doença avançada em final de vida e suas famílias. As bases de dados consultadas, entre Setembro e Novembro de 2020, foram Scopus, Embase e Web of Science. O material empírico foi composto por 35 artigos, dos quais foram extraídas informações do método e dos resultados em formulário do Google, organizados em planilha no programa Excel e analisados por aproximação temática. Constatou-se que famílias e cuidadores de instituições de longa permanência apresentam medos e anseios diante da dor, da dispneia e da parada cardiorrespiratória, resultando no chamado dos serviços da APH. Os profissionais da APH, ao se depararem com a situação, possuem receios em suspender intervenções e limitações quanto à formação para os cuidados em final de vida. Dessa forma, realizam procedimentos e tendem a encaminhar os pacientes para o hospital, local em que esses acabam morrendo. Sugere-se, em relação aos cuidados com a família, o suporte diante da finitude, por meio da articulação entre os serviços que integram a rede de urgência e emergência, os quais podem favorecer o acompanhamento por serviços da atenção domiciliar ou da própria atenção primária em saúde, visando a permanência no domicílio até a morte. Ademais, demonstra-se relevante o investimento em tecnologias de informação para o compartilhamento de dados clínicos que facilitem a tomada de decisão, bem como a aproximação com serviços especializados em cuidados paliativos.
KUALITAS DAN DAYA TERIMA YOGHURT SARI BUAH NAGA MERAH UNTUK PENDERITA HIPERKOLESTEROLEMIA
Authors:   Poltekkes Kemenkes Padang Indonesia, Kasmiyetti Kasmiyetti , Amri Zul ,   Poltekkes Kemenkes Padang Indonesia, Hasneli Hasneli ,   Poltekkes Kemenkes Padang Indonesia, Rahmayeni Susi ,   Poltekkes Kemenkes Padang Indonesia, Mushollini Fitria ,   Poltekkes Kemenkes Padang Indonesia
Published: January 2022

Salah satu faktor risiko terjadinya penyakit kardiovaskuler adalah hiperkolesterolemia. Buah Naga Merah mengandung antioksidan tinggi yang diyakini dapat menurunkan kadar kolesterol. Penelitian ini bertujuan mengetahui mutu organoleptik, mutu kimia dan daya terima yoghurt dengan penambahan sari buah naga merah sebagai minuman fungsional bagi penderita hiperkolesterolemia. Desain experiment quasy, rancangan non randomized control group design 1 kontrol dan 3 perlakuan. Uji tingkat kesukaan pada 30 panelis terlatih dan uji daya terima 30 pasien hipekolesterolemia. Uji sidik ragam 5 %, hasil analisa menunjukkan tidak ada perbedaan nyata tiap perlakuan terhadap mutu organoleptik dengan penambahan sari buah naga merah. Total bakteri asam laktat memenuhi SNI dan Daya Terima 96%. Perlu penelitian lanjutan untuk memeriksakan kadar Pb dan daya simpan yoghurt penambahan sari buah naga.
ANALISIS KADAR AKTIVITAS ANTIOKSIDAN, KADAR BESI, DAN pH PADA YOGURT SUSU KAMBING DENGAN PENAMBAHAN SARI KURMA (Phoenix dactylifera)
Authors:   Universitas Nahdlatul Ulama Surabaya Indonesia, Putri Endah Budi Permana , Anggraini Rahayu ,   Universitas Nahdlatul Ulama Surabaya Indonesia
Published: January 2022

Pencegahan virus COVID-19 dapat dilakukan dengan meningkatkan imunitas tubuh dengan mengkonsumsi pangan fungsional salah satunya yaitu yogurt. Susu kambing memiliki rasa yang kurang disukai sehingga dengan diolah menjadi yogurt dan penambahan sari kurma dapat lebih disukai. Di sisi lain, susu kambing dan kurma memiliki kandungan besi yang tinggi. Bahan yang digunakan yaitu susu kambing segar, bakteri asam laktat, kurma ajwa, dan sari kurma. Metode yang digunakan untuk menganalisis kadar aktivitas antioksidan adalah IC50 (Inhibition Concentration 50 Value), kadar besi (Fe) yaitu spektrofotometer UV – Vis, dan nilai pH menggunakan PH-meter. Hasil penelitian menunjukkan bahwa yogurt susu kambing dengan penambahan sari kurma memiliki kandungan antioksidan yang sangat lemah berdasarkan metode analisis antioksidan IC50. Ada perbedaan signifikan kadar besi pada yogurt susu kambing dengan penambahan sari kurma ajwa dengan nilai paling tinggi (5,7827 mg/100g) bila dibandingkan dengan yogurt susu kambing dengan penambahan sari kurma komersial (5,2351 mg/100g), yogurt susu kambing (4,4348 mg/100g) dan yogurt susu sapi (3,6839 mg/100g). Terdapat perbedaan nilai pH pada yogurt susu sapi dan yogurt susu kambing namun perbedaan tidak berbeda nyata pada yogurt dengan penambahan sari kurma ajwa dan komersial.
PENGARUH KONSENTRASI PATI KENTANG TERHADAP KARAKTERISTIK FISIKOKIMIA DAN ORGANOLEPTIK NUGGET IKAN PATIN-TEPUNG NANGKA MUDA
Authors:   Fakultas Teknologi Pertanian, Universitas Katolik Widya Mandala Surabaya, Indonesia, Wijaya Jessica Dewi , Utomo Adrianus Rulianto ,   Fakultas Teknologi Pertanian, Universitas Katolik Widya Mandala Surabaya, Indonesia, Setijawaty Erni ,   Fakultas Teknologi Pertanian, Universitas Katolik Widya Mandala Surabaya, Indonesia
Published: January 2022

Nugget merupakan salah satu produk restructured meat dengan prinsip penyatuan kembali potongan-potongan daging menjadi suatu bentuk utuh yang kompak dengan menambahan bahan pengisi (filler) dan pengikat (binder) yang dapat menentukan kualitas nugget. Pengolahan ikan patin menjadi nugget dengan modifikasi penambahan tepung nangka muda merupakan salah satu upaya diversifikasi hasil perikanan dan pertanian, meningkatkan juiciness, serta dapat meningkatkan kandungan serat nugget ikan patin. Penelitian pendahuluan pembuatan nugget ikan patin dengan proporsi 30% tepung nangka muda menunjukkan terjadinya penurunan tingkat kekenyalan dan nugget yang dihasilkan menjadi kurang kompak. Upaya peningkatan kualitas nugget dapat dilakukan dengan penambahan pati kentang sebagai filler dan binder dalam nugget. Tujuan penelitian ini adalah untuk mengetahui pengaruh konsentrasi pati kentang terhadap sifat fisikokimia dan organoleptik nugget ikan patin-tepung nangka muda. Rancangan penelitian yang digunakan adalah Rancangan Acak Kelompok (RAK) faktor tunggal yang terdiri dari enam taraf konsentrasi pati kentang, yaitu 3, 6, 9, 12, 15, dan 18% (b/b ikan patin-tepung nangka muda). Pengujian terhadap karaktertistik fisikokimia meliputi uji kadar air, WHC, daya serap minyak, kestabilan emulsi, tekstur, dan warna. Hasil penelitian menunjukkan adanya pengaruh konsentrasi pati kentang terhadap kadar air, WHC, daya serap minyak, tekstur, dan warna nugget. Peningkatan konsentrasi pati kentang dapat menurunkan kadar air, daya serap minyak, dan cohesiveness (konsentrasi pati kentang 15-18%), serta meningkatkan WHC, hardness, dan cohesiveness (konsentrasi pati kentang 3-12%).
PENGARUH PENAMBAHAN SENYAWA ANTIOKSIDAN PADA PENGGORENGAN KERUPUK BAWANG TERHADAP KUALITAS MINYAK GORENG DAN PRODUK
Authors:   Soegijapranata Catholic University Indonesia, Prayogo Bagus Kristian Hakiki , Harumi Mellia ,   Soegijapranata Catholic University Indonesia, Nugrahedi Probo Yulianto ,   Soegijapranata Catholic University Indonesia
Published: January 2022

Minyak goreng yang dipanaskan pada suhu tinggi dan dilakukan secara berulang dapat menurunkan kualitas dan mengubah karakteristik fisiko-kimianya. Oksidasi merupakan salah satu reaksi akibat penggunaan minyak goreng secara berulang. Penelitian ini bertujuan untuk mengetahui sifat dan kualitas minyak goreng dan produk setelah 3 hari penggunaan berulang dengan penambahan variasi konsentrasi antioksidan. Antioksidan alami dan sintetis seperti Alfa-tokoferol dan Tertiary Butyl Hydroquinone (TBHQ) ditambahkan ke dalam sampel minyak goreng. Kualitad minyak goreng (merek A, control, 90 dan 180 ppm Alfa-tokoferl, 90 dan 180 ppm TBHQ) setelah 10 kali penggunaan dalam sehari pada suhu tinggi (180 oC) dianalisis sebagai Free Fatty Acid (FFA), Thiobarbituric Acid (TBA), serta viskositas. Hasil menunjukkan bahwa kadar FFA, angka TBA, dan viskositas minyak semakin rendah seiring dengan besarnya penambahan konsentrasi antioksidan. Konsentrasi antioksidan optimal terdapat pada TBHQ 180 ppm. Uji hardness, kadar air, warna dan TBA dilakukan terhadap kerupuk bawang hasil penggorengan. Hasil menunjukkan bahwa antioksidan tidak berpengaruh terhadap hasil produk penggorengan.
Meme Kanseri Hastalarında hTERT Gen Ekspresyonunun Klinikopatolojik Önemi
Authors: DİRİCAN Ebubekir , KANKAYA Burak , TATAR Zeynep
Published: January 2022

Amaç: Bu çalışma, meme kanserinde insan telomeraz ters transkriptaz (hTERT) genin mRNA ekspresyonunun klinik önemini incelemeyi ve klinikopatolojik rolünü araştırmayı amaçlamıştır. hTERT geni hücre proliferasyonu, apoptoz ve hücre invazyonu gibi olaylarda rol almaktadır. Yüksek hTERT mRNA ekspresyonunun meme kanseri, mide, akciğer, glioblastoma, baş ve boyun gibi solid tümörlerde kötü prognoz ile ilişkili olduğu bildirilmektedir.

Gereç ve Yöntemler: 59 meme kanser ve sağlıklı kan örneklerinin RNA izolasyonları gerçekleştirildi. hTERT geni mRNA ekspresyonu Gerçek Zamanlı Polimeraz Zincir Reaksiyonu (RT-PZR) yöntemi ile analiz edildi. mRNA ekspresyon sonuçları 2-∆∆ct metoduyla kanserli ve sağlıklı örneklerde değerlendirildi. Klinik veriler toplandı ve bu verilerin hTERT gen ekspresyonu ile ilişkisi istatiksel olarak değerlendirildi.

Bulgular: Meme kanser hastalarında hTERT geni mRNA ekspresyonu sağlıklı örneklere kıyasla anlamlı derecede yüksekti (p=0,0211). Düşük hTERT geni ekspresyonu östrojen reseptör (ÖR) (+) ve insan epidermal büyüme faktör reseptörü 2 (HER 2) (+) olan hastalarda anlamlı derecede ilişkiliydi (sırasıyla p=0,0464; p=0,0080). hTERT geni ekspresyonu histolojik derece (grade) 3 hastalarda derece 2’ye kıyasla yüksek anlamlı bulundu (p=0,0389). Bununla birlikte hTERT ekspresyonun bazal benzeri histolojik tipte luminal A ve luminal B’ye kıyasla anlamlı derecede yüksek olduğu gösterildi (sırasıyla p=0,0160; p=0,0008).

Sonuç: Çalışmamızın bulguları, meme kanser hastalarında hTERT gen ekspresyonunun sağlıklı örneklere göre anlamlı olarak daha yüksek olduğunu gösterdi. Anormal hTERT gen ekspresyonu kanserojenez veya teşhiste önemli bir rol oynayabilir.
Venlafaksin Hidroklorürün Uzatılmış Salım Yapan Tablet Formülasyonlarının Geliştirilmesi ve Değerlendirilmesi
Authors: TORT Serdar , KODAN AKÇA Esra , OLĞAÇ Seval , SAAR Sinem , YILDIZ Ayşegül , ÜNAL İlay Sema , ÖZDAL Zeliha Duygu , TUĞCU DEMİRÖZ Fatmanur
Published: January 2022

Amaç: Depresyon, 250 milyondan fazla insanı yaştan bağımsız olarak etkileyen mental bozukluktur. Venlafaksin, antidepresan bir ilaçtır ve eski antidepresan ilaçlara göre daha az yan etki ile panik atak ve anksiyete tedavisinde kullanılır. Bununla birlikte, venlafaksin hidroklorür (VH), yeterli plazma-ilaç konsantrasyonunu sağlamak için günde üç kez dozlama gerektiren kısa yarı ömre sahiptir. Bu çalışmanın amacı, günde bir kez verilecek uzun süreli salım yapan VH tabletleri geliştirmektir.

Gereç ve Yöntemler: Kontrollü salım ajanı olarak polietilen oksit, sodyum aljinat, hidroksipropil metil selüloz, guar zamkı ve poliakrilik asit kullanıldı. Tabletler doğrudan basım yöntemi ile hazırlandı. Toz (yığın açısı, akış hızı, Carr indeksi ve Hausner oranı) ve tablet (ağırlık homojenliği, sertlik, friabilite) karakterizasyonları değerlendirildi. 24 saat boyunca in vitro salım çalışmaları yapıldı ve ilaç salım kinetikleri farklı modeller kullanılarak değerlendirildi.

Bulgular: Guar zamkı ile hazırlanan formülasyon dışında tüm formülasyonlar uygun Carr indeksi ve Hausner oranı gösterdi. Doğrudan basım yöntemi ile üretilen tabletler, ticari tablet ile karşılaştırıldı. Tüm formülasyonlar için uzun süreli VH salımı gözlendi. In vitro salım hızı test sonuçlarına göre, HPMC ve Carbopol polimerlerini içeren F1 formülasyonundan ilaç salımı, ticari tabletlere kıyasla benzer bulunmuştur.

Sonuç: Doğrudan basılmış VH tabletler, hasta uyumu ve diğer üretim yöntemlerine kıyasla daha az üretim aşaması ile ticari tabletlere tercih edilebilir bir alternatif olabilir.
Sedanter Kadın ve Erkekerde Beden Kitle İndeksi ile Pes Planus, Denge, Yaşam Kalitesi ve Ağrı Düzeyleri Arasındaki İlişki
Authors: KESKİN AKTAN Arzu , KUTLAY Özden
Published: January 2022

Amaç: Bu çalışmanın amacı sedanter erkek ve kadınlarda beden kitle indeksi ile pes planus, denge, yaşam kalitesi ve ağrı arasındaki ilişkinin araştırılmasıdır.

Gereç ve Yöntemler: Çalışmamıza 18-30 yaş aralığında, toplam 82 sedanter gönüllü (39 erkek, 43 kadın) katıldı. Katılımcıların fiziksel aktivite düzeyleri Uluslararası Fiziksel Aktivite Ölçeği ile değerlendirildi ve beden kitle indeksleri hesaplandı. Her iki ayak için pes planus değerlendirmesi Naviküler Düşme Testi (NDT) ile yapıldı. Statik denge ölçümü Tek Ayak Üstünde Durma testi ile, dinamik denge ölçümü ise Dört Adım Kare ve Zamanlı Kalk-Yürü testleri ile yapıldı. Yaşam kalitesinin değerlendirilmesinde Kısa Form-36 (SF-36) ölçeği kullanıldı, ağrı değerlendirmesi ise Vizuel Analog Skala (VAS) ile yapıldı.

Bulgular: BKİ ile yaş, kilo, NDT, Dinamik Denge-Zamanlı Kalk ve Yürü test puanları arasında pozitif yönde; Statik Denge, SF-36-Fiziksel fonksiyon, SF-36-Genel sağlık puanları arasında ise negatif yönde ilişki saptandı. Erkeklerde boy, kilo ve BKİ’ nin yanı sıra NDT-sağ ayak ölçümü daha yüksek bulundu. NDT sınıflamasına göre yapılan gruplamada pes planusu olan katılımcıların kilo, BKİ ve VAS (şiddetli) ölçümlerinin daha yüksek olduğu, ayrıca statik ve dinamik dengelerinin daha kötü olduğu görüldü.

Sonuç: Bulgularımız sedanter genç-erişkinlerde beden kitle indeksinin, pes planus, vücut dengesi ve yaşam kalitesi ile ilişkili olduğunu göstermekte, ayrıca pes planusun statik ve dinamik vücut dengesini olumsuz yönde etkilediğine işaret etmektedir.
COVID-19 Pandemi Sürecinde Çocuklardaki İnternet Bağımlılığı, Siber Mağduriyet Düzeyleri ve Algılanan Ebeveyn İzleminin İncelenmesi
Authors: SARIGEDİK Enes
Published: January 2022

süreleri artırdı. İnsanların evlerinde geçirilen sürelerine paralel olarak internette geçirdikleri süreler de arttı. Bu çalışma da bu gelişmelerin internet üzerinden zorbalığa uğrama ile olan ilişkisinin incelenmesi amaçlanmıştır.

Gereç ve Yöntemler: Katılımcılara çevrimiçi ortam üzerinden ulaşıldı. Annelerden; Sosyo-demografik form, Aile-Çocuk İnternet Bağımlılık Ölçeği, çocuklardan ise Siber Mağduriyet Ölçeği, Anne Baba İzleme Ölçeği doldurmaları istenmiştir. Katılmayı kabul eden katılımcılardan bilgilendirilmiş onamları alınmıştır. Toplam 104 anne ve çocuk ile çalışma tamamlanmıştır.

Bulgular: Kız cinsiyette, yaş ile siber mağduriyet ölçek puanları arasında istatistiksel olarak anlamlı pozitif yönlü zayıf bir ilişki bulunmuştur (r: 0,308, p=0,028). Sosyal medya hesabı olan çocuk ve ergenlerin siber mağduriyet puanları olmayanlara göre istatistiksel olarak anlamlı düzeyde daha yüksek bulunmuştur(p=0,002). Ölçeklerin birbirleri ile olan ilişkileri değerlendirildiğinde Aile-Çocuk İnternet Bağımlılık Ölçeği ile Siber mağduriyet düzeyleri arasında istatistiksel olarak anlamlı pozitif yönde zayıf bir ilişki olduğu saptanmıştır (r=0,248 p=0,011). Ergen grubunda hem Aile-Çocuk İnternet Bağımlılık Ölçeği hem de Siber mağduriyet ölçeği ile kısıtlayıcı izlem arasında istatistiksel olarak anlamlı pozitif yönde zayıf düzeyde ilişki bulunmaktadır (r=0,345 p=0,019; r=0,345 p=0,019).

Sonuç: COVID-19 sürecinde internet bağımlılığı ve siber mağduriyet gençler arasında hızla artmaktadır. Yaşın artması ve sosyal medya hesaplarının olması çocuk ve ergenlerde siber mağduriyet açısından risk yaratmaktadır. Aileler bu süreçte çocukları yakından izlemeli, internet kullanımı ve siber mağduriyet hakkında doğru bilgilendirmeler yapmalıdır, sınır koyma da aşırı kısıtlayıcı olmaktan kaçınmalıdırlar.
Eskişehir 112 İl Ambulans Servisi Çalışanlarında Bel Ağrısı ve Algılanan Stres Düzeylerinin Değerlendirilmesi
Authors: KILINÇ Ali , ÇALIŞKAN PALA Seval , PALA Veli Görkem , ARSLANTAŞ Didem , ÜNSAL Alaettin
Published: January 2022

Amaç: Çalışmada hastane öncesi acil sağlık hizmetleri (HÖASH) çalışanlarında en sık görülen kas-iskelet problemlerinden biri olan bel ağrısının ve algılanan stresin değerlendirilmesi amaçlanmıştır.

Gereç ve Yöntemler: Kesitsel tipteki bu çalışmada Eskişehir’deki HÖASH çalışanlarının %77,5’ine (n=378) ulaşıldı. Fonksiyonel Bel Ağrısı Skalası (FBAS) ve Algılanan Stres Ölçeği (ASÖ) kullanıldı. İstatistiki değerlendirmede Mann Whitney U, Kruskal Wallis, Spearman korelasyon ve binomial lojistik regresyon analizleri kullanılmıştır.

Bulgular: Çalışma grubunu oluşturanların %55,1’i (n=205) kadın olup yaş ortalaması ± SS 32,15 ± 7,52 yıl idi. Çalışanların %76,6’sı son 1 yılda bel ağrısı şikayeti olduğunu belirtti. Bel ağrısı riski, ön lisans ve üzeri öğrenim düzeyi olanlarda lise ve altına göre 1,97 (%95 GA; 1,07-3,62), sağlık sektöründe 6-10 yıl ve 11 yıl üzeri çalışanlarda 5 yıl ve daha az çalışanlara göre sırasıyla 3,46 (%95 GA; 1,66-7,22) ve 5,33 (%95 GA; 2,52-11,27), 24 saat çalışanlarda 24 saatten az çalışanlara göre 3,65 (%95 GA; 1,83-7,26), anne, baba ve kardeşlerinde bel ağrısı olanlarda olmayanlara göre 2,13 (%95 GA; 1,19-3,80) ve algılanan stres düzeyleri yüksek olanlarda düşük olanlara göre 1,11 kat (%95 GA; 1,03-1,20) daha fazlaydı. Genel sağlık durumunu iyi algılayanlarda orta ve kötü algılayanlara göre bel ağrısı 0,16 kat (%95 GA; 0,04-0,58) daha az olarak bulundu. HÖASH çalışanlarının ASÖ ve FBAS’dan aldıkları puanlar arasında negatif yönde zayıf bir ilişki bulundu (r=-0,186, p
Principles of Salvation undertaken according to Bible
Authors: Faot Agustinus , Octavianus Jonathan , Laurina Connie
Published: January 2022

Various polemics about the concept of salvation confuse God's people. The polemic

intended is the difference in understanding of what salvation that can be or cannot be

achieved. The problems are not only issues in the world of theology but are also developing

in churches in Indonesia. So the concept of salvation developed no longer lies in the Bible

but lies in the dogmatics of each church. It must be realized that the Christian faith stands

on the basis of the Bible, so the Bible must answer every doctrinal problem. Therefore in

this article will provide answers to the polemics of the concept of salvation according to

the Bible. This research uses exegesis methodology. The main purpose of this writing is to

convince God's people to understand the Bible comprehensively and to understand every

concept of Salvation subjectively.
The Impact Of Organizational Commitment On The Membership Growth In FGBMFI Chapter In East Java Region 1 In Surabaya
Authors: Tjiptobusono Aditia Djaja
Published: January 2022

The title of The Impact of Organizational Commitment on The Membership Growth in FGBMFI Chapter in East Java Region 1 in Surabaya, was chosen by the author in this research study. The author wants to know whether the organizational commitment can increase the membership growth, especially in FGBMFI Chapter in  East Java Region 1 in Surabaya. Pearson correlation coefficient and regression analysis, t-test and analysis of variance are used as the methods of analysis in this matter. Descriptive analysis was conducted to analyze the growth rate of members in FGBMFI Chapter in East Java Region 1 in Surabaya according to demographic groups. It turns out that organizational commitment has an influence, which is 39.4%, on the member growth in FGBMFI Chapter in East Java Region 1 in Surabaya.
Exploring the Effects of Economic Complexity and the Transition to a Clean Energy Pattern on Ecological Footprint From the Indian Perspective
Authors: Wan Xiaowen , Jahanger Atif , Usman Muhammad , Radulescu Magdalena , Balsalobre-Lorente Daniel , Yu Yang
Published: January 2022

The study explores the association between economic complexity, globalization, renewable and non-renewable energy consumption on the ecological footprint in the case of India from 1990–2018. The autoregressive distributed lag (ARDL) is applied to measure the long-run elasticity, while the vector error correction model (VECM) is applied to classify the causal path. The empirical findings demonstrate that economic complexity, globalization process, and renewable energy consumption play a dominant role in minimizing environmental degradation. In contrast, economic growth and non-renewable energy consumption are more responsible for increasing the pollution level in both the short and long run. Furthermore, the VECM outcomes disclose that there is long-run causality between ecological footprint and economic complexity. Moreover, the empirical outcomes are robust to various robustness checks performed for analysis to the consistency of our main results. The Indian government/policymakers should encourage a more environmentally friendly production process and eco-friendly technologies in exports to minimize environmental degradation.
The Impact of the D21 Method and Its Modification on Citizens’ Participation in Participatory Budgeting. The Case of the Czech Republic
Authors: Kukučková Soňa , Poláchová Marie
Published: January 2022

Participatory budgeting (PB) is often discussed as a tool to support active participation of citizens in the decision-making in the matters of the distribution of public resources. However, little was said about the possibility that the choice of a voting method used in the voting phase of the PB process could affect the participation in PB. In the Czech Republic, the Democracy 2.1 (D21) voting method is often used in municipalities implementing PB and additionally, it is promoted as a method to encourage more people to vote. This article aims to determine Czech municipalities with the D21 method and its modification, and to evaluate the impact of choosing these voting methods on participation rate in PB. The study suggests that the choice of a voting method is relevant for citizens´ engagement in voting. Based on the empirical findings, the D21 method and its modification are associated with a higher voter turnout in PB than another voting method. Further, the results underline the influence of external organizations offering online platforms for voting.
Participatory Budgeting: Case Study of Possible Causes of Failures
Authors: Soukop Michal , Šaradín Pavel , Zapletalová Markéta
Published: January 2022

Participatory budgeting is perhaps the most widespread and popular form of democratic innovation (DI). It is often identified as an appropriate tool to deepen the democracy at the local level. The text shows that this is not always the case, as some elected officials may use it as a innovation “façade” or its design suffers from various forms of imperfections leading to its failure to be implemented. The authors focus on the practice of participatory budgeting and its failures in the Czech Republic. Through the empirical testing of causal mechanism, the article reveals the main causes of that failure, in the case of its implementation in Prague 7 borough. The mechanism presented is based on the theory-testing minimal process-tracing design in which part of the findings of the previous research have been tested. It also attempts to support empirically only the significant steps of the mechanism between cause and outcome. In particular, the three scope conditions are tested: political support, sufficient funding for participatory budgeting and the existence of a source of know-how. Authors conclude that in the selected case, there was a domino effect of failure, with successive failures in all observed conditions, which ultimately led to a complete brake of causal mechanism and failure of participatory budgeting tool.
Specifications of Participatory Budgeting in Visegrad Group States and Possible Implementations for Slovakia
Authors: Mikuš Dalibor , Brix Richard , Šmatlánek Daniel
Published: January 2022

Participatory budget is an innovative tool for public policymaking, which is characterized by the particpation of residents of territorial administrative units. In the paper, authors focus on the evaluation of the participatory budget within the Visegrad Group, which is linked by specific ties due to the special development of this geopolitical area after the political and social changes in the late 1980s. Identifying the specifics of participatory budgeting in Poland, the Czech Republic, Hungary, and Slovakia is set as the main goal of the article, specifically evaluating the pilot project model, analysing the legislative framework, which regulates participatory budgeting, and extending this tool at the local level in terms of current statistics. As for the pilot projects, the authors identified differences in the following indicators: initiator of its implementation; participation of citizens and their position and powers in project design; participation in the decision-making on projects in terms of voting; whether a direct physical vote or online form was used. In addition, the authors evaluate the legal framework of the selected states in terms of presence of the primary or secondary regulation. Finally, the quantitative development of participatory budgets is monitored, while the potential impact of the COVID-19 pandemic is also reflected in the paper. Based on the data from other states of the Visegrad Group, in the final chapter the authors present optimization proposals, which they consider applicable in Slovakia. The authors identified at least three possible ways of amending the current Slovak legislation in order to improve the implementation of the participatory budget. The paper specifies the shortcomings in the form of low citizen participation in the drafting phase and in the voting process. The paper also identifies the same bottom-up implementation process in all V4 member countries. Poland is the only V4 country that has enshrined primary legislation on participatory budgets in its legal system.
Predictors, Determinant Groups, and Participatory Budgeting
Authors: Klun Maja , Benčina Jože
Published: January 2022

Recent developments in local public finance management in Slovenia indicate the local governments’ growing interest in introducing participatory budgeting as a decision-making tool, wherein part of local resources are used with citizen participation. Usually, the literature on participation budgeting analyses its effects, but our main research objective was to analyze the possible determinants influencing its implementation. The influence of political factors, sociodemographic factors, economic factors, and the capability of municipalities are examined here using binary logistic regression to predict a dichotomous dependent variable from a set of predictor variables. In binary logistic regression, predictable variables are the probability of one category being chosen. In this case, the authors calculated the probability that a municipality, described by selected prediction variables, would implement a participatory budget. The results of the analysis suggest six indicators that impact the probability of participatory budgeting adoption, proving the influence of four determinants on the decision to adopt such a measure.
Participation of Citizens in Public Financial Decision-Making in Serbia
Authors: Trtovac Šabović Mirela , Milosavljevic Milos , Benkovic Sladjana
Published: January 2022

Participation in the local public finance decision-making process in Serbia is not a new concept as it was implemented even during the ‘Titoistic’ period. However, direct participation is still in an infant phase altogether with the low interest of citizens in participating in local financial decision-making procedures. The aim of this paper is to explain the main types of civic participation in the local financial decision-making process (i.e., referendum voting on self-imposed contribution, participatory budgeting, and civic crowdfunding) and to focus on the main factors that lead to a low participation of citizens in such processes. Additionally, the article analyses how these factors affect general mistrust in politics and society. For this purpose, a total of N=421 citizens were interviewed. Using the principal component analysis, the following three main components for low participation were defined: 1) lack of knowledge, 2) lack of interest, and 3) lack of political will. Thereafter, using the regression analysis, the study confirmed that the first two components are statistically significant predictors for mistrust in politics and society.
Selected Factors Determining the Adoption and Use of Participatory Budgeting in Central and Eastern Europe
Authors: Klimovský Daniel , Junjan Veronica , Nemec Juraj
Published: January 2022

This is a summary article of the SJPS thematic issue on participatory budgeting in the Central and Eastern European region. Its authors provide an overview of the diffusion of participatory budgeting, and they classify relevant countries in terms of the pace of this diffusion into four different groups: frontrunners, early majority, later majority, and lagging adopters. In addition, they uncover various diffusion mechanisms that have been used. Since the research articles included in this thematic issue unpack various factors that influence the diffusion of the innovative practice of participatory budgeting in the specific settings of Central and Eastern Europe, the main goal of this article is to sum up their crucial findings and formulate several conclusions, including a few avenues for further research. A clear majority of countries in the region have already collected a relevant amount of experience with the adoption and further use of participatory budgeting. An analysis of the individual experiences reveals that the position and characteristics of mayors, organizational resources, and available capacities, as well as the quality of public trust, are likely to be important factors that determine the adoption and use of participatory budgeting in the region.
Effects of sodium selenite and selenium-enriched yeast on cardiometabolic indices of patients with atherosclerosis: A double-blind randomized clinical trial study
Authors: Khabbaz Koche Ghazi Mahdiyeh , Ghaffari Samad , Naemi Mohammad , Salehi Rezvaniyeh , Taban Sadeghi Mohammadreza , Barati Meisam , Namazi Shabestari Alireza , Kafil Behnam , Mesri Alamdari Naimeh , Soleimanzadeh Hamid , Tarighat-Esfanjani Ali , Roshanravan Neda
Published: January 2022

Introduction: Atherosclerosis and related cardiovascular diseases (CVDs) are the major causes of mortality worldwide. The available reports regarding the effects of selenium (Se) supplementation in the realm of atherosclerosis have been equivocal. The present investigation is aimed to assess the effects of sodium selenite and Se-enriched yeast supplementation on metabolic parameters among atherosclerotic patients. Methods: In this double-blind placebo-controlled randomized clinical trial, 60 patients diagnosed with atherosclerosis were randomly allocated into either 200 μg/day selenite, yeast, or placebo groups for eight consecutive weeks. Serum levels of lipid profile and glycemic indices were measured at the baseline and end of the intervention. Results: There were no significant within-or between-group changes in levels of total cholesterol, triglycerides, high-density lipoprotein cholesterol (HDL-c), fasting blood sugar, insulin, and homeostatic model assessment for IR throughout the study (P≥0.05). Only the low density lipoprotein cholesterol (LDL-c) levels were significantly lower in the yeast group in comparison with the placebo group (P= 0.015). Conclusion: The administration of Se-enriched yeast is significantly effective in decreasing LDL-c levels in patients with atherosclerosis. Additional clinical trial studies investigating the effect of Se administration on glucose homeostasis parameters and lipid profiles in atherosclerotic patients are suggested for a more definitive conclusion.
Characteristics and outcomes of hospitalized patients with cardiovascular complications of COVID-19
Authors: Jalali Farzad , Hatami Farbod , Saravi Mehrdad , Jafaripour Iraj , Hedayati Mohammad Taghi , Amin Kamyar , Pourkia Roghayeh , Abroutan Saeid , Javanian Mostafa , Ebrahimpour Soheil , Valizadeh Niloufar , Khosravi Bizhaem Saeede , Ziaie Naghmeh
Published: January 2022

Introduction: To address cardiovascular (CV) complications and their relationship to clinical outcomes in hospitalized patients with COVID-19. Methods: A total of 196 hospitalized patients with COVID-19 were enrolled in this retrospective single-center cohort study from September 10, 2020, to December 10, 2020, with a median age of 65 years (IQR, 52-77). Follow-up continued for 3 months after hospital discharge. Results: CV complication was observed in 54 (27.6%) patients, with arrhythmia being the most prevalent (14.8%) followed by myocarditis, acute coronary syndromes, ST-elevation myocardial infarction, cerebrovascular accident, and deep vein thrombosis in 15 (7.7%), 12 (6.1%), 10(5.1%), 8 (4.1%), and 4 (2%) patients, respectively. The proportion of patients with elevated high-sensitivity troponin I, N-terminal pro-B-type natriuretic peptide, left ventricular diastolic dysfunction, and heart failure with preserved ejection fraction was greater in the CV complication group. Severe forms of COVID-19 comprised nearly two-thirds (64.3%) of our study population and constituted a significantly higher share of the CV complication group members (75.9%vs 59.9%; P=0.036). Intensive care unit admission (64.8% vs 44.4%; P=0.011) and stay (5.5days vs 0 day; P=0.032) were notably higher in patients with CV complications. Among 196patients, 50 died during hospitalization and 10 died after discharge, yielding all-cause mortality of 30.8%. However, there were no between-group differences concerning mortality. Age, heart failure, cancer/autoimmune disease, disease severity, interferon beta-1a, and arrhythmia were the independent predictors of all-cause mortality during and after hospitalization. Conclusion: CV complications occurred widely among COVID-19 patients. Moreover,arrhythmia, as the most common complication, was associated with increased mortality.
Editorial for the Special Issue of EJKM 2021
Authors: Garcia-Perez Alexeis
Published: January 2022

Guest EditorAlexeis Garcia-Perez, Centre for Business in Society, Coventry University, UK

Supported byAnitha Chinnaswamy, Aston Business School, Aston University, UKVahid Jafari-Sadeghi, Aston Business School, Aston University, UK
Fostering Residential Demand Response through Developing Proactive and Elastic Demand Approaches. An Overview DR
Authors: Hussain Muhammad , Gao Yan , Xu Zhihong
Published: January 2022

Demand response (DR) is one of the major stakeholders in the smart grid and has been used as an energy reconciler between supply and demand. After a literature overview, the importance of the paper is enhanced by having a theoretical and behavioral-based analysis of DR in power systems. In this work, the potential factors that influence more DR among customers and the residential market as a whole have been discussed. The customers’ elastic demand approach can pave the way for adapting a responsive demand mechanism that ensures the system reliability and cost effective measures. Alternatively, this approach can make the program more effective and supportive in serving the social welfare as whole.