bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical and genetic analysis of 18 patients with KCNQ2 mutations from South China
Authors: Cao Binbin , Peng Bingwei , Tian Yang , Wang Xiuying , Li Xiaojing , Zhu Haixia , Shen Huiling , Chen Wenxiong
Published: May 2024

Background. We aimed to delineate the genotype and phenotype of patients with KCNQ2 mutations from South China.
Methods. Clinical manifestations and characteristics of KCNQ2 mutations of patients from South China were analyzed. Previous patients with mutations detected in this study were reviewed.
Results. Eighteen epilepsy patients with KCNQ2 mutations, including seven self-limited neonatal epilepsy (SeLNE), two self-limited infantile epilepsy (SeLIE) and nine developmental and epileptic encephalopathy (DEE) were enrolled. The age of onset (p=0.006), mutation types (p=0.029), hypertonia (p=0.000), and seizure offset (p=0.029) were different in self-limited epilepsy (SeLE) and DEE. De novo mutations were mainly detected in DEE patients (p=0.026). The mutation position, EEG or the age of onset were not predictive for the seizure or ID/DD outcome in DEE, while the development of patients free of seizures was better than that of patients with seizures (p=0.008). Sodium channel blockers were the most effective anti-seizure medication, while the age of starting sodium channel blockers did not affect the seizure or development offset. We first discovered the seizure recurrence ratio in SeLNE/SeLIE was 23.1% in South China. Four novel mutations (c.790T>C, c.355_363delGAGAAGAG, c.296+2T>G, 20q13.33del) were discovered. Each of eight mutations (c.1918delC, c.1678C>T, c.683A>G, c.833T>C, c.868G>A, c.638G>A, c.997C>T, c.830C>T) only resulted in SeLE or DEE, while heterogeneity was also found. Six patients in this study have enriched the known phenotype caused by the mutations (c.365C>T, c.1A>G, c.683A>G, c.833T>C, c.830C>T, c.1678C>T).
Conclusion. This research has expanded known phenotype and genotype of KCNQ2-related epilepsy, and the different clinical features of SeLE and DEE from South China.
Comprehensive study on catfish (Clarias gariepinus) burger as affected by fortification using carrot and cauliflower
Authors:   Food Technology Department, Faculty of Agriculture, Kafrelsheikh University, Kafrelshiekh, Egypt, HAMMAD ASMAA , OWON MOSTAFA AHMAD ,   Food Technology Department, Faculty of Agriculture, Kafrelsheikh University, Kafrelshiekh, Egypt, SALAMA ABD ELBASET ABD ELAZIZ ,   Food Technology Department, Faculty of Agriculture, Kafrelsheikh University, Kafrelshiekh, Egypt, BISAR BADIAA ABD ELRAHMAN ,   Food Technology Department, Faculty of Agriculture, Kafrelsheikh University, Kafrelshiekh, Egypt
Published: May 2024

This work was conducted to prepare catfish burgers (CFB) using some fresh vegetables such as carrot, cauliflower and mixture of them. Vegetables were partially substituted of catfish meat at different levels of (2.5, 5, 10, 15 and 20%), compared with the control sample (without vegetables). Sensory properties were done in different sessions by a trained panel and generic consumers to assess product acceptability. The best samples were 2.5, 5 and 15% of cauli􀃀 ower, carrots and mixture, respectively, which were selected from organoleptic values and analyzed. The addition of vegetables to catfish burger showed better cooking properties like decrease cooking loss, increase moisture retention, cooking yield and shrinkage. Proximate chemical composition, minerals, and vitamins (A, C and E) were determined. A little decrease in moisture and protein of prepared samples was reported compared with the control, furthermore, carrot and cauliflower improved the ash, fiber, fat and minerals content of CFB, except potassium (K) in burger fortified with 5% carrot as well as Mg, Zn and Fe in burger fortified with cauliflower and mixture vegetables. Also, adding investigated samples to CFB increased vitamin A and E compared with the control, but vitamin C was not defined in all samples including the control.
The contribution of manure to antibiotic resistance and the spread of antibiotic resistance genes in soil: a review
Authors:   University of Bucharest, Faculty of Biology, Doctoral School of Ecology, Romania, JAGA IOANA MIHAELA , MANOLE ALINA ,   University of Bucharest, Faculty of Biology, Doctoral School of Biology, Romania, SÂRBU ECATERINA ,   University of Bucharest, Faculty of Biology, Doctoral School of Ecology, Romania, MARUTESCU LUMINITA GABRIELA ,   The Research Institute of the University of Bucharest, University of Bucharest, Romania, POPA MARCELA ,   The Research Institute of the University of Bucharest, University of Bucharest, Romania, CHIFIRIUC MARIANA MARIANA CARMEN ,   The Research Institute of the University of Bucharest, University of Bucharest, Romania,   Academy of Romanian Scientists, Bucharest, Romania,   The Romanian Academy, Bucharest, Romania, POSTOLACHE CARMEN ,   University of Bucharest, Faculty of Biology, Doctoral School of Ecology, Romania,   Department of Systems Ecology and Management of Natural Capital, University of Bucharest, Bucharest, Romania
Published: May 2024

The intensive use of antibiotics, worldwide, in animal husbandry, has led to the development and enrichment of different environments in antibiotic-resistant bacteria (ARB) and antibiotic-resistance genes (ARGs). Moreover, the subsequent application of manure contributes to the emergence of antimicrobial resistance (AMR) in soil. The spread of ARB and ARGs through trophic networks and potential human transmission indicate the need for innovative treatment approaches and strategies to reduce manure contaminants.
Mesenchymal stem cells attenuate amiodarone-induced pulmonary fibrosis in rats via blockade of inflammation and TGF-B1/Smad3/ S100A4 signaling
Authors:   Department of Biochemistry, Faculty of Science, Ain Shams University, Cairo, Egypt, ABDEL HALIM ALYAA S. , AHMED HANAA H. ,   Hormones Department, Medicine and Clinical Studies Research Institute, National Research Centre, Giza, Egypt, A􀵶 liation ID: 60014618,   Stem Cells Lab, Center of Excellence for Advanced Sciences, National Research Centre, Giza, Egypt, A􀵶 liation ID: 60014618, AGLAN HADEER A. ,   Hormones Department, Medicine and Clinical Studies Research Institute, National Research Centre, Giza, Egypt, A􀵶 liation ID: 60014618,   Stem Cells Lab, Center of Excellence for Advanced Sciences, National Research Centre, Giza, Egypt, A􀵶 liation ID: 60014618, MOHAMED MOHAMED R. ,   Department of Biochemistry, Faculty of Science, Ain Shams University, Cairo, Egypt
Published: May 2024

Aim: This study aimed to clarify the anti-fibrotic potential of bone marrow-derived mesenchymal stem cells (BM-MSCs), compared to conditioned media (CM), in amiodarone (AD)-induced lung fibrosis. Methods: A total of 64 Wistar rats were categorized into eight groups: negative control group, positive control group, 3 AD-challenged-BM-MSCs-treated groups (1, 2 and 4 months) and 3 AD- challenged-CM-treated groups (1, 2 and 4 months). Serum macrophage in􀃀 ammatory protein 2 (MIP-2) evels were measured. Gene expression levels of TGF-􀈕1, SMAD3 and S100A4, were estimated in the lung tissues. Results: Treatment with BM-MSCs/CM mediated a significant reduction in serum MIP-2 concentrations, while downregulating AD-induced up-regulation of lung TGF-􀈕1, SMAD3 and S100A4 gene expression levels. BM-MSCs transplantation revealed better effect than CM in mitigating lung fibrosis. Conclusion: BM-MSCs advance anti-fibrotic effect on lung fibrosis by targeting inflammatory response and TGF-B1 signaling.
Current status on in vitro propagation of sea buckthorn (Hippophae sp.)
Authors:   University of Bucharest, Faculty of Biology, Department of Genetics, Intr. Portocalelor 1-3, sector 6, Bucharest, Romania, DUTA-CORNESCU GEORGIANA , CONSTANTIN NICOLETA ,   University of Bucharest, Faculty of Biology, Department of Genetics, Intr. Portocalelor 1-3, sector 6, Bucharest, Romania, POJOGA MARIA DANIELA ,   University of Bucharest, Faculty of Biology, Department of Genetics, Intr. Portocalelor 1-3, sector 6, Bucharest, Romania, SIMON-GRUI􀄥A ALEXANDRA ,   University of Bucharest, Faculty of Biology, Department of Genetics, Intr. Portocalelor 1-3, sector 6, Bucharest, Romania
Published: May 2024

Sea buckthorn, Hippophae spp., a dioecious shrub, is considered for a very long time a wonder plant, due to the fact that the leaves and berries contain a myriad of biological compounds which have been used in many domains related to human and animal health. For that reason, there is a huge market demand for elite varieties, resistant to biotic and abiotic stress. Because the traditional breeding and propagation methods are limited in their ability to produce such varieties so, plant biotechniques, encompassing plant tissue culture and genetic engineering have been applied. However, the development of optimal in vitro multiplication strategies of Hippophae spp. is very difficult, because sea buckthorn explants are sensitive to their sterilization treatment, plant growth regulators and nutrient composition of the culture medium. This paper is a review of the progress made in the application of the modern biotechnological tools in order to preserve genetic resources for mass production of sea buckthorn and create new varieties.
Influence of using low voltage electrostatic field during freezing and thawing processes on beef quality
Authors:   Agricultural Engineering Department, Faculty of Agric. Kafrelsheikh University, 33516 Egypt, ELSBAAY ATEF MOHAMED , ABOUELHANA NABIHAH H. ,   Agricultural Engineering Department, Faculty of Agric. Kafrelsheikh University, 33516 Egypt, ELSEBAIE ESSAM MOHAMED ,   Food Technology Department, Faculty of Agric. Kafrelsheikh University, Egypt, MANSOUR BASUONY MAHMOUD ABDELHAKIEM ,   Agricultural Engineering Department, Faculty of Agric. Kafrelsheikh University, 33516 Egypt
Published: May 2024

This study examined the effects of LVEF-assisted freezing-thawing on beef loin (Longissimus dorsi) quality and texture. In this work, the quality of beef specimens at 15, 30, and 45 cm from the LVEF plate (test group) and without LVEF treatment (control group) was examined during freezing-thawing. LVEF aided freezing (LVEFF) sped up beef freezing and thawing by 32.46% and 32.60% at 30 cm layer spacing (LVEF-30). LVEF30 created the smallest, most homogeneous ice crystals and less injured muscle fibre tissue. SEM indicated that LVEF30 preserved muscle fibre and perimysium structure, and muscle fibre gaps did not expand. Z-line and M-line were generally intact, while A-band and I-band were distinct and readable, indicating that LVEF30 preserved myo􀂿 brillar structure efficiently. LVEF30’s L*, a*, and C values were substantially higher than the control group (P0.05) and fresh meat (P0.05). LVEF-30 reduced thawing loss, cooking loss, and drip protein content by 52.10%, 31.313%, and 15.97%. In conclusion, LVEF can improve the quality of thawed beef by reducing quality loss during freezing-thawing, and 30 cm is the best distance from the electrostatic field generation plate.
Las Memorias de Mamá Blanca de Teresa de la Parra
Authors: Vejarano Elizabeth
Published: May 2024

En el presente ensayo se articulan puntos clave para darle sentido al tema de la esperanza femenina, que inspira en toda su magnitud a la novela Las Memorias de Mamá Blanca de Teresa de la Parra: la Sororidad, para ilustrar que las alianzas entre mujeres son la ruta de la solidaridad y el liderazgo femenino frente a la hegemonía patriarcal; la figura ausente/política del padre y sus consecuencias en la estructura familiar y en la convivencia social y la relación con la madre, portadora del saber patriarcal, pero también fuente de la lengua viva: lengua madre y por ello fundadora de mundos femeninos.
Balboa y Oviedo: Antecedentes y formación de la cultura colombiana.
Authors: Martínez Fabio
Published: May 2024

La cultura europea entró a América del sur por el Caribe colombiano. A partir de allí, los intentos por crear vasos comunicantes entre el Caribe y el Pacífico no se hicieron esperar. El 1o de noviembre de 1510, Vasco Núñez de Balboa llega al golfo de Urabá en la tripulación capitaneada por el bachiller Enciso. Allí funda la primera ciudad en el continente, llamada Santa María la Antigua del Darién. Balboa pensó unir los dos mares, y los cientos de conquistadores que hicieron su primera experiencia a todo lo largo de la costa norte colombiana.El presente ensayo es un intento por mirar los procesos fundacionales acerca de lo que, tres siglos más tarde, se denominará como la Nación colombiana.
Forensic Aspects of the Study of Latent Papillae Pattern Prints on the Epidermis of a Deceased Person. Summary of the Doctoral Thesis
Authors:   ,   Rīga Stradiņš University, Zīle Aelita
Published: May 2024

This Doctoral Thesis is a systematic study of the theoretical and practical aspects of possibility of visualisation of papillae pattern prints on the skin of a deceased person. The aim of the Thesis is to conduct a theoretical and practical study on the visualisation of latent papillae pattern prints on the epidermis of a deceased person, identifying potential forensic and technological challenges and issues and providing proposals for improvement of their solution. The study was based on a review of scientific literature and articles: in medicine – on the structure of human skin and the substance forming the latent papillae pattern prints; in forensic medicine – on the factors affecting the preservation of papillae pattern prints on the skin of a deceased person; in forensics – on the relief of latent papillae pattern prints and their genesis, preconditions for the preservation of papillae pattern prints, technological possibilities of their visualisation and analysing the course and results of experiments carried out abroad. In the framework of the study the author carried out an independent experiment exploring the genesis and reflection of latent papillae pattern prints on the skin of a deceased person, visualised and copied them using different visualisation agents and removal agents, studied and analysed the influence of gender, age, skin condition, duration of contact on the acquisition of traces suitable for identification of a person. The Thesis consists of introduction, four chapters divided into fourteen sub-chapters, conclusions, which present findings and proposals of the study, a list of literature used and annexes. The Doctoral Thesis was developed Rīga Stradiņš University, Latvia. Defence: at the public session of the Promotion Council of of Law on 21 May 2024 at 15.00 in the Hippocrates Lecture Theatre, Dzirciema Street 16, Rīga Stradiņš University and remotely via online platform Zoom. 5.5 Law; Sub-Sector – Theory of Forensic Science and Investigation Field Work. Keywords: human epidermis; latent papillae pattern prints; genesis of papillae pattern prints; visualisation; copying; identification.
Latentu papillārlīniju rakstu pēdu uz miruša cilvēka epidermas izpētes kriminālistiskie aspekti. Promocijas darbs
Authors:   ,   Rīgas Stradiņa universitāte, Zīle Aelita
Published: May 2024

Promocijas darbs “Latentu papillārlīniju rakstu pēdu uz miruša cilvēka epidermas izpētes kriminālistiskie aspekti” ir sistēmisks pētījums par latentu papillārlīniju rakstu pēdu vizualizēšanas iespējamību uz miruša cilvēka ādas teorētiskā un praktiskā aspektā. Pētnieciskā darba mērķis ir veikt teorētisku un praktisku pētījumu latentu papillārlīniju rakstu pēdu vizualizēšanā uz miruša cilvēka epidermas, apzinot iespējamās kriminālistiskās un tehnoloģiskās problēmas, un sniegt priekšlikumus to risinājuma pilnveidei. Pētījuma ietvarā tika apkopota un pētīta zinātniskā literatūra un raksti: medicīnā par cilvēka ādas uzbūvi un latentu papillārlīniju rakstu pēdu veidojošo vielu; tiesu medicīnā par papillārlīniju rakstu pēdu saglabāšanos ietekmējošajiem faktoriem uz miruša cilvēka ādas; kriminālistikā par latentu papillārlīniju rakstu pēdu reljefu un pēdu ģenēzi, papillārlīniju rakstu pēdu saglabāšanas priekšnosacījumiem, pēdu vizualizēšanas tehnoloģiskajām iespējām un analizējot ārvalstīs veikto eksperimentu gaitu un rezultātus. Tāpat arī pētījuma ietvarā autore veica patstāvīgu eksperimentu, pētot latentu papillārlīniju rakstu pēdu ģenēzi un atspoguļojumu uz miruša cilvēka ādas, pēdu vizualizēšanu un pārkopēšanu, lietojot dažādus vizualizēšanas un izņemšanas aģentus, pētīja un analizēja dzimuma, vecuma, ādas stāvokļa, kontakta ilguma ietekmi uz personas identifikācijai derīgu pēdu iegūšanu. Promocijas darba struktūru veido ievads, četras nodaļas, kas iedalītas apakšnodaļās, un nobeigums, kurā izklāstīti pētījuma secinājumi un priekšlikumi, izmantotās literatūras avotu saraksts un pielikumi. Promocijas darbs izstrādāts Rīgas Stradiņa universitātē, Latvijā. Aizstāvēšana: Tiesību zinātnes promocijas padomes atklātā sēdē 2024. gada 21. maijā plkst. 15.00 Hipokrāta auditorijā, Dzirciema ielā 16, Rīgas Stradiņa universitātē, un attālināti, tiešsaistes platformā Zoom. 5.5. tiesību zinātne; apakšnozare – kriminālistika un operatīvās darbības teorija. Atslēgvārdi: cilvēka epiderma; latentas papillārlīniju rakstu pēdas; pēdu ģenēze; vizualizēšana; pārkopēšana; identifikācija.
Latentu papillārlīniju rakstu pēdu uz miruša cilvēka epidermas izpētes kriminālistiskie aspekti. Promocijas darba kopsavilkums
Authors:   ,   Rīgas Stradiņa universitāte, Zīle Aelita
Published: May 2024

Promocijas darbs “Latentu papillārlīniju rakstu pēdu uz miruša cilvēka epidermas izpētes kriminālistiskie aspekti” ir sistēmisks pētījums par latentu papillārlīniju rakstu pēdu vizualizēšanas iespējamību uz miruša cilvēka ādas teorētiskā un praktiskā aspektā. Pētnieciskā darba mērķis ir veikt teorētisku un praktisku pētījumu latentu papillārlīniju rakstu pēdu vizualizēšanā uz miruša cilvēka epidermas, apzinot iespējamās kriminālistiskās un tehnoloģiskās problēmas, un sniegt priekšlikumus to risinājuma pilnveidei. Pētījuma ietvarā tika apkopota un pētīta zinātniskā literatūra un raksti: medicīnā par cilvēka ādas uzbūvi un latentu papillārlīniju rakstu pēdu veidojošo vielu; tiesu medicīnā par papillārlīniju rakstu pēdu saglabāšanos ietekmējošajiem faktoriem uz miruša cilvēka ādas; kriminālistikā par latentu papillārlīniju rakstu pēdu reljefu un pēdu ģenēzi, papillārlīniju rakstu pēdu saglabāšanas priekšnosacījumiem, pēdu vizualizēšanas tehnoloģiskajām iespējām un analizējot ārvalstīs veikto eksperimentu gaitu un rezultātus. Tāpat arī pētījuma ietvarā autore veica patstāvīgu eksperimentu, pētot latentu papillārlīniju rakstu pēdu ģenēzi un atspoguļojumu uz miruša cilvēka ādas, pēdu vizualizēšanu un pārkopēšanu, lietojot dažādus vizualizēšanas un izņemšanas aģentus, pētīja un analizēja dzimuma, vecuma, ādas stāvokļa, kontakta ilguma ietekmi uz personas identifikācijai derīgu pēdu iegūšanu. Promocijas darba struktūru veido ievads, četras nodaļas, kas iedalītas apakšnodaļās, un nobeigums, kurā izklāstīti pētījuma secinājumi un priekšlikumi, izmantotās literatūras avotu saraksts un pielikumi. Promocijas darbs izstrādāts Rīgas Stradiņa universitātē, Latvijā. Aizstāvēšana: Tiesību zinātnes promocijas padomes atklātā sēdē 2024. gada 21. maijā plkst. 15.00 Hipokrāta auditorijā, Dzirciema ielā 16, Rīgas Stradiņa universitātē, un attālināti, tiešsaistes platformā Zoom. 5.5. tiesību zinātne; apakšnozare – kriminālistika un operatīvās darbības teorija. Atslēgvārdi: cilvēka epiderma; latentas papillārlīniju rakstu pēdas; pēdu ģenēze; vizualizēšana; pārkopēšana; identifikācija.
SAÚDE EMOCIONAL: UM ESTUDO SOBRE A CONTAÇÃO DE HISTÓRIA COMO ESTRATÉGIA PARA O DESENVOLVIMENTO NO CONTEXTO ESCOLAR
Authors: Almeida Roela Thais , Fragatti Cristovam Poliana
Published: May 2024

Introdução: A saúde emocional tem ganhado espaço na sociedade atual, por decorrência disto, nota-se que a escola é um ambiente primordial para a propagação desta conscientização. Por conta dessa relevância, um meio eficaz para a propagação desta temática ou até mesmo de outras, é através da contação de histórias, pois quando se ouve histórias a criança compreende significados e temas que anteriormente poderiam ser difíceis de entender.
Objetivo: Por meio da contação de história, objetiva-se realizar um projeto sobre saúde emocional com crianças do 3º ano do ensino fundamental. Instigando-os a entenderem seus sentimentos e como lidar com os mesmos. Assim, para que eles adquiram consciência não apenas do que eles sentem, mas do que os outros ao seu redor também podem sentir.
Método: Será realizado por meio de três etapas, a primeira sendo a contação de história do livro “O monstro das cores” (adaptado), no qual serão usados recursos didáticos para a melhor visualização e compreensão dos alunos referente ao assunto abordado. Na segunda parte do projeto, os alunos levarão para casa um material denominado “diário das emoções” e deverão preenchê-lo no período de uma semana, no qual englobará três períodos durante o dia que contarão sobre como estão se sentindo e o porquê do sentimento. Na terceira parte, os pais ou familiares terão contato com o “jogo dos sentimentos”, no qual deverão jogar juntamente com a criança e após a realização do jogo em casa, eles deverão responder um questionário conforme a experiência que compartilharam no jogo.
Resultados (esperados / parciais): Espera-se que ao final deste projeto, os alunos que participarem adquiram um maior conhecimento sobre os sentimentos, tanto individual quanto coletivo. Aprendendo a identifica-los, sabendo como lidar com eles e entendendo a importancia de compartilhar estas emoções com os outros ao seu redor, desde o ambiente escolar até no ambiente familiar.
Descritores: Contação de história; Saúde emocional; Sentimentos.Eixo temático: Ciências Humanas.
DESENVOLVIMENTO DE UM WEBSITE PARA OS CURSOS DE PÓS-GRADUAÇÃO DA FADBA
Authors: Souza Neves Roseane , Silva Santos Bruna , Souza Lago Erik
Published: May 2024

Introdução: O site da PÓS-GRADUAÇÃO tem como foco atender as pessoas que te interesse em cursar pós-graduação, consequentemente o website irá rodar em computadores como Windows, MacBook, Android e Apple entre outros dispositivos.Sua tela inicial dará ao usuário informações sobre os cursos de pós-graduação, sobre o campus, localização da faculdade, terá alguns botões indicando quais cursos tem disponíveis, qual área o aluno poderá se matricular.
Objetivo: O Website da PÓS-GRADUAÇÃO tem como objetivo facilitar a vida de pessoas que estão à procura de pós-graduações, com apenas alguns clicks, conseguiram conhecer mais sobre a FADBA e os cursos dos quais ela oferece.
Método: O Website foi construindo com a plataforma do Wordpress, onde foi desenvolvido todas a paginas e conteúdo assim encontrado no mesmo, foi utilizado alguns plugins como o elementor que auxiliar na edição das paginas, post entre outros , Vlibras onde foi possivel adicionar acessibilidade ao website , Forminator onde foi desenvolvido o formulário de inscrição, o Website é dividido por área de estudo, cada uma traz os cursos relacionados as mesmas.
Resultados (esperados / parciais): o website irá atender a demanda da realização de uma pré-matrícula onde serão obtido os dados do interessado, podendo ele ter a acesso aos cursos disponíveis as modalidades, locais disponíveis e custo do mesmo, podendo assim ser um ambiente flexível atendendo pessoas não ouvintes que precisem de ajuda, tendo o VLibras como auxiliador para guiar essas pessoas, esperado que possamos inferir a opção de pagamento no site tonando a matrícula dos interessados mais prática e fáceis, de forma que de onde ele esteja ele consiga realizar a mesma, tendo em mente também acrescentar mais alguns recursos de acessibilidade para o site este item também se encontra como esperado.
Descritores: pós-graduação; libras; desenvolvimento.Eixo temático: Ciências Tecnológicas e Inovação.
UMA PROPOSTA PARA ENVOLVER PARA ENVOLVER OS MEMBROS DA IASD Parto, na missão integral através dos dons e talentos
Authors: Pereira Borba Jackson , Rodrigues dos Santos Manoel
Published: May 2024

Introdução: Não é possível, esperar ter apoio de pessoas para participarem em atividades que não tem afinidade, nem sabem fazer. Sendo assim, esse critério serve para atividades evangelística. Partindo desse pressuposto, iremos propor uma proposta que visa envolver IASD do porto de Maragojipe-BA, em ações baseadas nos dons de cada membro, desenvolvendo ministérios que promova unidade da congregação e conquiste novos membros. Quando Cristo esteve aqui na terra, Seu ministério era pautado em duas frente, anunciar o evangelho a todos que estavam perdidos, e ensinar seus discípulos a serem pescadores de almas. Esse trabalho tem o propósito de promover o envolvimento da IASD do porto, no evangelismo integrado com base nos dons e talentos. Essa igreja será o protótipo da proposta que poderá ser implantado em outras realidades.
Objetivo: Desenvolver uma proposta de como envolver a membresia da IASD Porto, Maragojipe-Ba, no evangelismo integrado por meio dos dons e talentos dos membros.
Método: A metodológica adotado neste trabalho será básica estratégica, com o objetivo descritivo de pesquisa. Na perspectiva da metodologia qualitativa de investigação bibliográfica. Bogdan e Biklen (1994) definem características da investigação qualitativa, que consideram os principais pontos de pensamento e formas de se intervir nessa perspectiva. Será usado o procedimento bibliográfico para realizar esse estudo.
Resultados (esperados / parciais): Esse trabalho pretende envolver a membresia da igreja adventista do porto de Maragojipe-BA, no evangelismo integrado que conta com a unidade dos membros na realização de ações solidarias na cidade. Vamos dividir a igreja com base nos dons e talentos. O propósito desse estudo é fortalecer a igreja em sua experiência de conduzir pessoas de uma maneira que cumpra a missão com a habilidade de cada membro.
Descritores: Evangelismo, Dons, Talentos, Missão
Eixo temático: Estudos históricos e teológicos
APLICACIÓN WEB PARA LA FORMULACIÓN DE ALIMENTOS PARA ENGORDE BOVINOS EN ZONAS ALTOANDINAS
Authors: Angel Sullon A. , Wilber Tipo Mamani Noe
Published: May 2024

Introdução: La economía de la región altiplánica, está basada fundamentalmente en las actividades agropecuarias, siendo la producción de especies: bovinos, alpacas, llamas y ovinos las más representativas. La producción y crianza de vacunos de engorde, se realiza de manera sub desarrollada en el departamento de Puno, en la crianza de los bovinos, se encuentra cuatro pilares de la producción (Alimentación, Sanidad, Manejo ganadero), el mal manejo de estos pilares da como consecuencia bajos ingresos y altos precios en la producción.La alimentación en los animales bovinos de engorde es muy importante en los primeros 60 días, así como durante el crecimiento 30 días y acabado 15 días. Una dieta bien equilibrada y un manejo apropiado mejoran la producción, la reproducción y la salud de los animales. Para cubrir las necesidades nutricionales del ganado bovino, se debe asegurar que las porciones de alimentos incluyan agua, materia seca, proteínas, fibras, vitaminas y minerales en porciones suficientes y bien equilibradas, considerando además el precio de la ración de alimento, por lo que el especialista en nutrición debe recomendar la ración de menor costo en función de sus cálculos de balanceo nutricional, esto comúnmente se calcula utilizando un mecanismo de tanteos. Sumado a las limitaciones de los produtores como falta de computadora personal, capacitación en informática básica y el desconocimiento de las técnicas de balanceo óptimo al mínimo costo de raciones para animales por parte de los ganaderos de la región. 
Objetivo: Monitorear la elaboración de dietas para animales bovinos de engorde, estableciendo las proporciones adecuadas en las que las distintas materias primas de la zona deben ser combinadas para cumplir con los requisitos nutricionales del animal, buscando minimizar los costosMétodo: Para el adecuado balanceo de raciones se empleó el algoritmo programación lineal simplex LP. La programación lineal es un algoritmo matemático mediante el cual se resuelve un problema indeterminado, formulado por medio de ecuaciones lineales buscando constantemente perfeccionar la función objetivo.La formulación de los alimentos se realizó con los productos propios de la zona altiplánica (Puno). Para que la solución sea utilizada por los ganaderos en las zonas altoandinas se emplea la tecnología web. Donde el proceso del calculo se realiza en un servidor web con lenguaje de programación PHP, Python, Javascript y como gestor de base datos MYSQL.Resultados (esperados / parciais): 1. Aplicación WEB para la FORMULACIÓN DE ALIMENTOS PARA ENGORDE BOVINOS EN ZONAS ALTOANDINAS. 2. Esta aplicación web apoyará al monitoreo del equilibrio de alimentación para los ganados de miles de agricultores ganaderos y los datos que se generen servirán para futuras investigaciones.
Descritores: Programación Lineal, Formulación de alimentos, Engorde de bovinos, Monitoreo.
Bridging Proactive Market Orientation to Startups’ Marketing Approach: Theoretical Background and Case Studies
Authors: Şahin Begüm
Published: May 2024

Rapid change of global market dynamics makes the survival of startups difficult. This study investigates the integration of startups' marketing approach with proactive market orientation in order to adapt these changing dynamics of the market. Customer orientation, new-product development, innovation orientation and competitiveness are explained as encouraging components of proactive market orientation to be robust and long-run in the in competitive environment. Case studies of the paper are involving the most innovative and valuable brands of the world as well as customer-centric oriented. Findings showed that the startups in the research sample that integrate innovation and proactive market orientation are tend to grow-up rapidly and achieve success in long run. The most fundamental purpose of the paper is to emphasize the importance of marketing approach through those companies’ proactive behaviors. With the continues startup culture, the companies can give inspirations for the early-stage ventures while designing their marketing strategies. The article presents a strategic point of view based on theoretical background of the phenomenon and recommends a holistic roadmap for practitioners in the journey of entrepreneurship also pioneering for the further studies.
Kamu Kurumlarında Örgütsel Muhalefet ve İşe Yabancılaşma Arasındaki İlişkinin Belirlenmesi
Authors: Yılmaz Kılıçkaya Fatma
Published: May 2024

Bu çalışma, kamu sektöründeki mevcut çalışanların örgütsel muhalefet ile işe yabancılaşma algıları arasındaki potansiyel ilişkiyi araştırmayı amaçlamaktadır. Çalışma, özellikle böyle bir ilişkinin var olup olmadığını ortaya koymayı, işe yabancılaşmayı etkileyen örgütsel muhalefetin boyutlarını belirlemeyi ve işe yabancılaşma davranışının demografik faktörler arasında önemli ölçüde farklılık gösterip göstermediğini değerlendirmeyi amaçlamaktadır. Veriler Erzincan ilinde kamu sektöründe aktif olarak çalışan 307 çalışandan anket yoluyla toplanmıştır. Toplanan veriler istatistiksel yazılım paketleri SPSS 24 ve AMOS 17 kullanılarak analiz edilmiştir. Sonuçlara göre, dikey muhalefet ile işe yabancılaşma arasında anlamlı bir negatif ilişki olduğu ortaya konmuşken yatay muhalefet ile işe yabancılaşma arasında anlamlı bir pozitif ilişkinin varlığı belirlenmiştir. Ayrıca, fark analizlerine göre işe yabancılaşmanın cinsiyet, medeni durum ve yaşa göre önemli ölçüde değiştiği ortaya konmuştur. Tukey testi sonuçları, erkek çalışanlar, evli çalışanlar ve orta yaşlı çalışanlar arasında daha yüksek düzeyde işe yabancılaşma olduğunu göstermektedir. Ancak eğitim düzeyi ve çalışma saatlerine göre işe yabancılaşmada anlamlı bir farklılık gözlenmemiştir. Örgütsel muhalefet kamu kurumlarında en iyi şekilde yönetilerek yatay muhalefet davranışları dikey muhalefet davranışlarına döndürülerek işe yabancılaşmanın önüne geçilebilmektedir.
Türk Devletleri Teşkilatı Örnekleminde AR-GE Harcamaları ve Doğrudan Yabancı Yatırımların Ekonomik Büyüme Üzerine Etkisi
Authors: Tıraş Hacı Hayrettin
Published: May 2024

Bu çalışmanın amacı, Türk Devletleri Teşkilatı ülkelerinde doğrudan yabancı yatırımlar ve Ar-Ge harcamalarının ekonomik büyümeye olan etkilerini ortaya koymaktır. Doğrudan yabancı yatırımlar, Ar-Ge harcamaları ve gayri safi yurtiçi hasılanın değişken olarak kullanıldığı bu çalışmada, değişkenlere ait 1997-2021 dönemi yıllık verileri yeni nesil panel ekonometrik yöntemlerle analiz edilmiştir. Dinamik panel veri yöntemlerinin kullanıldığı çalışmada, tahminler için Westerlund (2006) ve AMG eşbütünleşme testlerinden yararlanılmıştır. Analizler sonucunda Türk Devletleri Teşkilatı ülkelerinde, Ar-Ge’ye yapılan harcamaların uzun dönemde ekonomik büyümeye anlamlı bir katkı sağladığı, doğrudan yabancı yatırımların etkisinin ise istatistiksel olarak anlamsız olduğu ortaya konulmuştur. Türk Devletleri Teşkilatı ülkelerinde ekonomik büyümenin sağlanabilmesi için öncelikle; doğrudan yabancı yatırımların ülkeye çekilebilmesi adına iktisadi, hukuki ve altyapı bakımından tüm engellerin kaldırılması, ülkede, ekonomik, siyasi ve güvenlik açısından istikrarlı bir ortamın oluşturulması, Ar-Ge faaliyetlerinin teşvik edilerek kamu ve özel sektör Ar-Ge süreçlerinin özendirilmesi faydalı olacaktır.
S. Holm, J. Lewis. Abortion: pro et contra / trans. from Engl. A. V. Nekhaev
Authors:   Omsk State Technical University, Nekhaev A. V.
Published: May 2024

The article provides a critical review of some of the most common arguments actively used in the abortion debate. Based on the notion of moral personhood, the main groups of such arguments (no full moral status, full moral status, and gradualism) are identified and characterized. Separate consideration is given to the right of pregnant women to abortion, the legal defense of the fetus’ right to life, and the practice of using the medical concept of viability in law.
A. R. Galloway. The autism of reason / trans. from Engl. Z. M. Neustroev
Authors:   Tyumen State University, Neustroev Z. M.
Published: May 2024

The article examines the key principles of François Laruelle’s non-philosophical project and analyzes it comparatively with the Kantian categories of a priori, a posteriori, analytical and synthetic. It discovers certain parallels between the a priori and transcendental account of non-philosophy, its theory of subjectivity and autistic perception of the real.
Transforming Novosibirsk into the capital of Siberia in the early 1920s
Authors:   Institute of History, Siberian Branch, Russian Academy of Sciences, Papkov S. A.
Published: May 2024

The development of Novonikolaevsk (Novosibirsk) and its transformation into a city of all-Siberian importance is connected with the construction of the Trans-Siberian Railway and the growth of the city’s economy due to its favorable geographical location. The decision about Novonikolayevsk as a residence of Siberia’s governing bodies was made in a hurry, with the resistance of various interested parties and was finally approved in the spring of 1921 in the conditions of acute crisis caused by the consequences of the civil war. In such an environment the mass transfer from Omsk and the organization of all-Siberian institutions in Novonikolaevsk began, with the simultaneous creation of provincial government bodies in the city as well. As a result, this led to enormous problems with the accommodation of numerous employees with their families and strenuous efforts to overcome the housing crisis. Radical measures were taken to solve the difficulties: emergency commissions were set up to search for and distribute premises, mass evictions outside the city of residents not connected with service in Soviet institutions were carried out. But these measures had only a minor effect — the housing crisis and the shortage of office space persisted for decades.
Modeling the digital transformation of industrial holdings
Authors:   Dostoevsky Omsk State University, Miller A. E. , Rudenko N. S. ,   Dostoevsky Omsk State University
Published: May 2024

The article reflects the achieved results of research on methodological provisions related to the application of economic models in the digital transformation of industrial holdings. The methodology of using economic models under consideration made it possible to identify the target orientation and the main tasks of digital transformation. The characteristic features of the proposed methodology should be considered: generalization of the signs of digital transformation; argumentation of distinctive properties that affect the development of economic models in the digital transformation of industrial holdings. The studied aspects make it possible to clarify the conceptual provisions of the classical theory of digital transformation of economic systems, in terms of studying problematic situations arising in the process of digital transformation of industrial holdings, as well as substantiating concepts such as modeling, digital transformation, models of digital transformation of industrial systems, to highlight the main stages of development of digital transformation of industrial systems. As part of the methodological implementation of the proposed methodology, an instrumental approach is considered that allows to systematize the tools of digital transformation of industrial systems in the context of digital business models, digital technologies and platform solutions, as well as to argue the key features of each of the tools. The advantage of the instrumental approach is the possibility of studying the established economic models of digital transformation and substantiating the author’s model of digital transformation of an industrial holding. The proposed model allows you to: optimize the configuration of manufactured products and processes of its life cycle in terms of optimizing the added value of an industrial holding; integrate systems and processes, as well as the value chain of an industrial holding, the components of which are: optimization of production, environmental safety, cost reduction, asset productivity, productivity improvement, profitability growth and increase in the value of the holding.
Incompetent managers — modern realities in Russian companies
Authors:   Department of Culture  of the Administration of the city of Omsk, Medvedev E. V.
Published: May 2024

In the article, the author raises the question of the incompetence of modern managers. The purpose of the study is to analyze such a category as managers, as well as to identify the reasons for their incompetence and offer recommendations for improving the situation. In conclusion, the author draws a conclusion about the work done and proposes a set of measures to increase the level of competence of our managers. The results of the study can be used in the practical activities of the country’s enterprises, as well as in the authorities.
The development of Russian federalism in the 1990s (on the example of the Omsk region)
Authors:   Omsk State Technical University, Novikov M. S.
Published: May 2024

In the framework of the presented article, the author analyzes the process of management transformation in the Omsk region in the 1990s as the formation of federalism in the Russian Federation. Later, the author of the article plans to carry out similar work in relation to the Altai Territory and the Tyumen region. Based on the available scientific developments and introducing into circulation a wide range of sources, the author of the work identifies the features of the development of federalism in the Omsk region within the framework of the system of socio-political and economic relations. Omsk region had serious industrial and agricultural potential, but also raw materials problems, exacerbated by the transition to market relations. The local leadership put forward the idea of regionalization of economic reform, which required the presence of a strong authoritarian business executive in power. But the active privatization carried out by external forces led to rapid bankruptcy, which did not suit the local leadership, and the population is not satisfied with the decline in living standards. In the Omsk region, this situation leads to increased support for left-wing parties. As part of the national administrative construction, the Azov German National District was created in the Omsk region. The idea of creating the territorial autonomy of the Siberian Tatars, triggered by the process of privatization of the oil industry, was stopped by transferring it to owners living outside the Omsk region.
Some notes on the relationship between Adorno and the Southern Epistemology
Authors: Silva Gustavo Ruiz da , Matheus Daniel Lopes Prado
Published: May 2024

This paper aims to develop an understanding of how the culture industry still operates in the postcolonial era. To this end, the first part of this paper will look at Adorno and Horkheimer’s reading of modernity, touching on how instrumental reasoning can lend itself to barbarism, along with an exposition of Adorno’s analysis of the culture industry. The second part will present decolonial theory, its critique of European modernity and, particularly, its focus on neo-imperialism. This theory will then be put alongside critical theory, analyzing their differences concerning racial issues and how their critique of capitalism may represent a meeting point between the two theories. Finally, the conclusion will consider all previous elements to explain the connection between the Culture industry and its current strategy in former colonial areas.
O homem como fim terminal no projeto de paz perpétua kantiano
Authors: Santos Cleiton Marcolino Isidoro dos
Published: May 2024

O objetivo deste artigo é refletir sobre a temática do homem como fim terminal no projeto de paz kantiano, considerando a necessidade de compreender o papel do indivíduo, enquanto sujeito moral, nos passos para a paz perpétua. Para isso, efetua-se uma análise dividida em duas partes, na qual se avaliará, num primeiro momento, o conceito de fim terminal na filosofia kantiana e suas correlações nos âmbitos do progresso do gênero humano e sua consequente dignidade; e, num segundo momento, o papel do homem enquanto sujeito moral atuante na formação de uma comunidade civil capaz de administrar o direito e seus decorrentes no pensamento do direito público kantiano. Por fim, será exposto o papel do homem, enquanto fim terminal da criação, na superação de sua condição mecanicista de existência para sua consequente atuação como sujeito moral na criação de uma sociedade civil que ruma em prol da efetiva paz perpétua.
O Ensino da Filosofia nas Instituições do ensino fundamental e universitário angolanos: da utilidade à essencialidade
Authors: Valentim Inácio , Moço Feliciano Nanga
Published: May 2024

This article addresses the pressing issue of the essential importance of teaching Philosophy, often questioned for its utility, especially in the Angolan educational context. It emphasizes the urgent need to implement Philosophy courses to educate academically prepared professionals. Under the auspices of contemporary philosophers such as Imbamba, Valentim, Pondé, and others, this article argues that, despite utilitarian societies, Philosophy provides crucial skills such as critical and argumentative thinking, essential for shaping reflective citizens. It is imperative to analyze the relevance of teaching Philosophy in Angolan institutions, considering the challenges faced by teachers. Furthermore, the teaching of Philosophy is not an academic luxury but a crucial necessity for the intellectual and ethical development of all citizens. The importance of Philosophy as a discipline dedicated to promoting essential skills, such as analysis, criticism, and argumentation, crucial for democratic societies, should be highlighted. In the face of the devaluation of the Humanities, especially Philosophy, it is opportune to appeal to public administrators to humanize Angola by integrating humanistic courses into curricula, aiming to educate not only qualified professionals but also conscious and engaged citizens. Philosophy, ipso facto, is presented as a possible "salvation" for the new youth, providing a space for existential questioning amidst an educational system often marked by commercialism and a lack of academic merit.
A problemática da reforma do ensino da filosofia em Angola
Authors: Bastos Feliciano Moreira
Published: May 2024

This work is a logical result of the discussions that took place in 1991 in the context of the formation of the new political mentality in Angola. The discussions discussed above continued in the academy based on the reflections entitled “Process of reforming the teaching of Philosophy in Angola: some epistemological and methodical aspects”, and as a response, the article by Professor Muanamoni Matumona “The teaching of Philosophy in Angola” appeared. It was an imperative need to develop reforms in the teaching of philosophy due to the spirit of social changes existing in the country. This meant the restructuring and construction of a new model and paradigm of education and teaching, in which Philosophy was integrated. Our analysis focuses on understanding the reform process at three crucial moments: The teaching of philosophy in the post-colonial era and the current moment. With this simple theoretical contribution, we take as our main reference the intention of interacting, implicitly, two issues that title it: epistemology and methodology, without losing sight of the accentuated treatment of the theoretical foundations of the teaching and study of philosophy in Angola.
Myocardial infarction in non-obstructive coronary artery (MINOCA) in a young girl with multidrug poisoning
Authors: Moniruzzaman Md , Paul Amal Krishna , Bulbul K M Adnan , Islam Md Shariful , Hasan Md Nahid
Published: May 2024

A 24-year-old girl was admitted to the emergency room with chest pain, abdominal discomfort and excessive sleeping tendency after taking some unprescribed medications. She had no risk factors for cardiovascular disease. On query, she gives a history of taking multiple medications available in her room due to some emotional outbreak. Her relatives give a history of taking paracetamol 1000 mg, cephradine 2500 mg, propranolol 100 mg, bilastine 160 mg and hydroxyzine 200 mg. None of these drugs have proven to cause myocardial infarction (MI) at this dosage. Initial ECG showed sinus bradycardia which can be because of taking propranolol. But 2 hours after admission, she developed severe chest pain and at that time ECG showed gross segment (ST) depression. Troponin-i was found to be raised. After initial management, a coronary angiogram was done which revealed normal epicardial coronaries. Patient was managed symptomatically and she recovered completely.