bluuebunny/crossref_metadata_2025 huggingface dataset:
Sistem Informasi Transparansi Dana Desa Kabupate Sumenep Berbasis Android
Authors: Susilowati, S.Kom.,M.Kom Arda Gusema
Published: April 2022

From this modern and sophisticated era the village inspired writers do not have to make benner to publish it to the community, just open the internet and enter the data into the Android application Village Fund Transparency in Kab. Sumenep online and the general public can be accessed. This system is about the budget village funds in an online android application, for people who want budget funds in their villages including in other villages.The process of this system works, the village admin must first log in unless the village admin user name and password are created by superadmin. After that, the admin will manage the village fund budget data then the admin can input the village budget data into the application. Basically, the author issued this information system in addition to facilitate the process of inputting data on village budget funds, the author also wants to introduce the progress of the internet, one of which is based on Android. Need everyone, from any group can use the internet positively.
SISTEM PREDIKSI JUMLAH PENUMPANG DI BANDAR UDARA JUANDA SURABAYA DENGAN METODE DOUBLE EXPONENTIAL SMOOTING
Authors: Yaqin Ainul , Budi Agus Setia , Susilo Purnomo Hadi
Published: April 2022

Bandar udara merupakan salah satu infrastruktur penting yang diharapkan dapat mempercepat pertumbuhan ekonomi masyarakat. Bandar udara berfungsi sebagai simpul pergerakan penumpang atau barang dari transportasi udara ke transportasi darat atau sebaliknya, salah satunya adalah Bandar Udara Internasional Juanda. Namun perlu dilakukan manajemen yang baik pada bandar udara karena kurangnya penjadwalan yang tertata. Dibutuhkan sistem untuk mengurangi kesalahan yang sering terjadi dan sistem yang mendukung. Penelitian ini bertujuan untuk menangani dan memberikan solusi terbaik untuk mengatasi permasalahan perhitungan jumlah penumpang pesawat di Bandar Udara Internasional Juanda.Dalam hal ini penulis mengadakan penelitian tentang prediksi calon penumpang pesawat pada Bandar Udara Internasional Juanda menggunakan metode Double Exponential Smoothing yang nantinya diharapkan dapat memberikan solusi terhadap permasalahan perhitungan penumpang pesawat untuk memprediksi calon penumpang pesawat sehingga dapat ditentukan penjadwalan yang tepat dengan jumlah pesawat yang diperlukan.Implementasi sistem ini menggunakan website dengan framework codeigniter dengan tingkat akurasi hasil mencapai 98% didukung dengan pola data yang sesuai, dalam hal ini data jumlah penumpang pertahun memiliki pola data statis yang mengandung data trend. Tingkat akurasi data diperoleh dari metode testing menggunakan Mean Absolute Percentage Error yang hasilnya kurang dari 25%.
Perancangan Software The Smart Tourism Bali Dengan Android
Authors: Sulistyanto Sulistyanto
Published: April 2022

Tourism is an important sector in the development of a region. Especially for the island of Bali. It is not uncommon for Bali to be one of the largest contributors to tourism revenue in Indonesia. Almost every corner of the island of Bali has extraordinary tourism potential. One of them is Jembrana Regency, where Jembrana Regency is the gateway to the island of Bali which clearly has a very ideal geographical location and has its own tourist attraction. Along with technological developments, namely Smartphones and Android operating systems which are very widely used by humans. Android has an open source system where anyone can create an application that will be paired with the Android system. By utilizing the Geographic Information System (GIS) it is very easy to find tourist location points. and can easily add new tourist points. The Water Fall development method was chosen because it has structured stages with each stage having to be completed before the next stage. Therefore, there is a Curik Bali the Smart Tourism Application Design with Android which will be an application to introduce every tourist place in Jembrana Regency.
Communicating European Integration in the Age of the World Wars: Print Media Discourses on the Unity of Europe, 1914-1945
Authors: Greiner Florian
Published: April 2022

This paper argues that the communication of European integration by the media did not begin with the European unification process after 1950. It draws upon a broad definition of the term “European integration” favoured by modern historiography, and in so doing shows that in the first half of the 20th century journalists communicated various notions of the unity of Europe to their readers. By linking media history and discourse analysis, the article examines three different facets of mediating European integration in German, British and American newspapers between 1914 and 1945. It traces “integrational thinking” in press coverage in three different sectors in particular, namely politics, economy and culture. Although discourses on continental unity were of course ambivalent and far from pointing straight towards European integration in the sense of a present-day European Union, they played an important role in the age of the World Wars. The article thus conceptualises a long-term historical perspective on communicating European integration.
From Informing to Interacting? Exploring the European Commission's Communication Strategy "to be all ears"
Authors: Van Brussel Annelies
Published: April 2022

Since 2001 the European Commission has paid increasing attention to two-way communication in its institutional communication strategy. Besides informing the public, the Commission’s strategy has become orientated towards listening to and engaging in a dialogue with citizens. This article explores the rhetoric of the Commission regarding its institutional communication strategy from 2001 to the present time and studies in depth the dialogic dimension of this strategy. This contribution extends the study of the Commission’s communication strategy by offering new insights into the development of the dialogic approach and the Commission’s current understanding of communication. Furthermore, defining institutional two-way communication as a means to facilitate a link between decision making and public opinion, I contribute to the debate on the European public sphere. The data used for the analysis originate from document analysis and semi-structured elite interviews with Commission officials. The analysis indicates the gradual nature of the shift between 2001 and 2009 from a one-way informing approach to a two-way communicating approach. The dialogic dimension in the Commission’s communication strategy is found to be more restricted in terms of subjects for discussion and facilitation. There are indications that engaging in a dialogue and interaction have been played down and are being managed through other means outside the formal communication strategy.
Political Communication in Europe: The Cultural and Structural Limits of the European Public Sphere
Authors: Bijsmans Patrick
Published: April 2022

Seoane Pérez discusses the issue of the EU’s perceived communication deficit, arguing that this is not the result of a lack of commitment from EU leaders and journalists, but rather of cultural and structural limitations. Based on an analysis of the situation in two regions, Galicia in Spain and Yorkshire in the UK, he claims that there are two important challenges that limit the EU’s democratic potential: a lack of ‘domesticisation’ and a lack of ‘politicisation’.
EU Think Tank Fora as Transaction Cost Reducers: A Study of Informal Interest Intermediation in the EU
Authors: Perez Marybel
Published: April 2022

By examining the organisational structure of EU think tank fora (seminars, workshops and conferences), this article proposes that fora can play the role of transaction cost reducers in EU policymaking. I argue that certain aspects of EU policymaking, including i) controlled processes of consultation, ii) diminishing costs of management, and iii) the risk of state capture, incentivise EU institutions to outsource part of the consultation activity to policy actors that can help EU institutions fulfil their informational and legitimacy needs. I argue that think tanks are able to play this role because they i) reduce information asymmetries by connecting a wide variety of policy actors and ii) act as intermediaries that mitigate opportunistic behaviour. The empirical assessment reveals that the dimensions characterising transactions are present in EU think tank fora. It shows that policy actors that do not usually participate in formal consultation processes frequently attend fora where they meet representatives of EU institutions, particularly Parliament and Commission representatives.
Do All Roads Lead to the Same Europe? Reconsidering the Pro-/Anti-Integration Yardstick to Measure National Party Positions Towards the EU: The Case of Belgium
Authors: Jadot Clément
Published: April 2022

Mapping national political party attitudes towards the EU is crucial in explaining the current state of the EU and is key to understanding political alliances on European affairs. Although important, literature on the topic remains constrained by the idea that positions on European integration can be located on a single ‘pro-/anti-axis’. The aim of this paper is to demonstrate why one-dimensional typologies lead to cumbersome and misleading evaluations of party positions. Based on Easton’s theory of political support, the research undertaken hypothesises that such classifications are unable to solve the problem of divergent orientations from one sector to another. Taking Belgium as an example, I explain why Belgian political parties, generally labelled as unanimously ‘pro-integration’, can be considered as divided regarding the EU. The research is primarily based on qualitative analysis of 2009 European manifestos and interviews with party elites conducted from May to July 2010.
The Role of EU Pre-accession Assistance in the Establishment of National Coordination Structures for EU Funding: The Case of Croatia
Authors: Antonopoulos Eleftherios , Bachtler John
Published: April 2022

Coordination at the national level is an essential part of the EU policy process. This article analyses the effects of EU pre-accession programmes on the development of national-level structures for the coordination of EU funds in Croatia. The article is based on an in-depth case study of the Croatian coordination structures for EU funding, using a three-step analytical framework of adaptation. The empirical research focuses on the role and influence of the Croatian Central State Office for Development Strategy and Coordination of EU Funds (CODEF). The main finding was that pre-accession assistance played a decisive role in the establishment and early support of national coordination structures. However, holistic reform in the state sector was not achieved and the new institutions were often challenged by domestic opposition structures. The research provides useful insights for the literature on Europeanization in accession countries, and for EU pre-accession policy.
The External Dimension of the EU’s Fight against Organized Crime: The Search for Coherence between Rhetoric and Practice
Authors: Carrapico Helena
Published: April 2022

Since the external dimension of the European Union’s Justice and Home Affairs (JHA) began to be considered, a substantial amount of literature has been dedicated to discussing how the EU is cooperating with non-member states in order to counter problems such as terrorism, organized crime and illegal migration. According to the EU, the degree of security interconnectedness has become so relevant that threats can only be adequately controlled if there is effective concerted regional action. This reasoning has led the EU to develop a number of instruments, which have resulted in the exporting of certain elements of its JHA policies, either through negotiation or socialization. Although the literature has explored how this transfer has been applied to the field of terrorism and immigration, very little has been written on the externalisation of knowledge, practice and norms in the area of organized crime. This article proposes to bridge this gap by looking at EU practice in the development of the external dimension of organized crime policies, through the theoretical lens of the EU governance framework.
From Idealism to Realism? EU Preferential Trade Agreement Policy
Authors: Garcia Maria
Published: April 2022

This article examines how the EU’s ‘conflicted power’ in trade has played out within its preferential trade agreement (PTA) strategies with third parties. It does this by providing an overview of how approaches to the EU’s external trade policies have evolved over time, especially since the end of the Cold War. Tracing changes in discourse in the EU’s consolidated trade policy demonstrates how the policy objectives have evolved from what could be characterised as a soft and even normative power to a much more realist one, attempting to safeguard its position in the international economic order. Notwithstanding these changes, explained by a combination of international context and ideational preferences, an underlying overall continuity has remained in terms of the main economic interests to be realised through trade policy, which presents a portrait of the EU as a rational and realist (if sometimes conflicted) actor in the global economy.
Multiple Arenas and Diverse Techniques of Securitisation: The Case of the EU’s Visa Regime towards Turkey
Authors: Baysan Alper
Published: April 2022

Between 2009 and 2010, five Western Balkan countries were granted Schengen visa exemptions by the EU for the short travel of their citizens to the Schengen area in return for signing readmission agreements. Turkey, in contrast, was only offered a vague promise for the initiation of a visa liberalisation “dialogue” in return for initialling the readmission agreement. Taking this development as a genuine research puzzle the present article asks: What are the domestic dynamics that have driven this differential outcome? This article argues that the EU’s ongoing restrictive visa regime towards Turkey stems from the issue’s securitisation in certain member states (Germany, Austria and the Netherlands). Security-framing practices thereby occurred in both the political (elite-level discourse) and bureaucratic arena (visa-issuing process) as part of the same security dispositif. Two crucial implications follow from the findings: on the one hand, European visa authorities seem to follow their own visa-issuing policies despite regulations put in force at the EU level (Visa Codex). On the other hand, the purported theoretical divide between the Copenhagen and Paris School’s approaches to securitisation seems empirically rather disadvantageous. Treating these theoretical lenses as distinct may lead researchers to miss out on interrelated securitisation practices.
Could and Should Britain have Joined the European Exchange Rate Mechanism in 1979? A Personal Memoir
Authors: Franklin Michael
Published: April 2022

A personal memoir by Sir Michael Franklin.
Seroprevalencia del virus de la leucemia bovina en rodeos lecheros del Departamento Iriondo, Santa Fe, Argentina
Authors: Luciani M. E. , Gorordo M. L. , Margineda C. A. , Rüegger M. J. , Magnano G.
Published: April 2022

El objetivo de este trabajo fue determinar la seroprevalencia del virus de la leucemia bovina (VLB) en rodeos lecheros de la Provincia de Santa Fe. Se procesaron 747 muestras mediante la técnica de inmunodifusión en gel de agar. Se realizó un análisis chi-cuadrado para evaluar la asociación entre la categoría y la general, que fue del 79,1%, siendo la prevalencia por categorías de 82,1% para vacas, 56,2% para vaquillonas y 54,5% para toros. En el análisis estadístico se observó una asociación de seropositividad. Los resultados de prevalencia intra-predial fueron entre el 63% y el 96%. La prevalencia estadísticamente significativa entre adultos y seropositividad, fue teniendo éstos 4 veces más chances de ser seropositivos que las vaquillonas. La elevada seroprevalencia del VLB hallada, demuestra que el virus está ampliamente distribuido en los rodeos lecheros de la región sur de la Provincia de Santa Fe.
Prevalencia de Eimeria sp y estudio morfométrico de ooquistes hallados en canes domésticos de Perú
Authors: Torrel T. S. , Vargas L. A. , Murga C. A. , Huaman V.
Published: April 2022

La eimeriosis es una enfermedad causada por un protozoario del género Eimeria que afecta a todos los animales silvestres y domésticos. Dado que en Perú no existen reportes previos y en otras regiones de Latinoamérica la prevalencia es nula o baja en perros domésticos, el objetivo del presente trabajo fue determinar la prevalencia de Eimeria sp en canes de la ciudad de Cajamarca mediante un análisis coproparasitológico, utilizando el método de Faust y efectuando el estudio morfométrico de los ooquistes. Se obtuvieron aleatoriamente 206 muestras fecales en la zona Este de Cajamarca, las cuales fueron inmediatamente procesadas en el Laboratorio de Parasitología Veterinaria de la Universidad Nacional de Cajamarca, Perú. La prevalencia de Eimeria sp fue de 10,68% en canes domésticos. En el estudio morfométrico de los ooquistes, se determinaron medidas de largo y ancho, que presentaron promedios de 21,73 pm de largo y 17,77 pm de ancho para la forma ovoide; 16,40 pm de largo y 15,31 pm de ancho para la forma esférica, y finalmente 25,54 y 18,51 pm respectivamente para la forma elipsoidal. Estos resultados prueban la presencia e infección leve por Eimeria sp en perros domésticos en la serranía norte del Perú, sugiriendo además, futuros estudios del protozoario para evitar riesgos o afecciones a la salud pública.
Diseño y validación de cebadores para el gen Calmegin en alpacas
Authors: Ganoza L. , Moscol F. S. , Ugarelli A. , Evangelista V. S.
Published: April 2022

En la presente comunicación breve se describe el primer diseño y validación de cebadores para el gen Calmegin en alpacas. Se observó mediante electroforesis horizontal que los amplicones diseñados cumplían con el tamaño predicho en forma in silico por lo que se concluyó que es posible diseñar cebadores in silico para el gen de Calmegin en alpaca y validarlos mediante la técnica de PCR.
Análise da produção científica internacional sobre lesão por pressão e uso de colchões: estudo bibliométrico
Authors: Viana Rocha Francisca Cecília , Lima Mario Oliveira , Gomes Adriana Vasconcelos , Nogueira dos Santos Fernanda Kaline , Viana Rocha Lucas Pazollinni
Published: April 2022

Este estudo objetiva mapear a produção científica internacional sobre lesões por pressão e colchões. Realizou-se um levantamento bibliométrico e cientométrico utilizando os termos de busca: “pressure ulcer*”, “mattress*” e “beds” na base de dados Web of Science/Clarivite Analytics, entre os anos 1991 e 2017. Após filtros de refinamento, encontramos 310 registros de publicação em 139 periódicos distintos. Os principais resultados das análises foram a quantidade de artigos em evolução; os top journals da temática; autores com maior número de publicações; artigos publicados por áreas de estudos e os artigos mais citados. Os resultados das citações globais e locais foram analisados e discutidos como meio de difundir o conhecimento produzido acerca da evolução tecnológica sobre os colchões versus a relação pressão corporal e o surgimento das lesões por pressão.
Primary versus interval debulking surgery in the management of ovarian cancer patients, current data summary
Authors: Psomiadou Victoria , Fotiou Alexandros , Iavazzo Christos
Published: April 2022

Objective: Optimal management of ovarian cancer patients have been investigated by several centers and have been discussed in a great number of published articles. Aim of this article is the review of current data regarding this lethal malignancy treatment. Moreover, we discuss the ongoing trials regarding primary or interval cytoreductive surgery after neoadjuvant chemotherapy. Mechanism: We reviewed the relevant literature regarding ovarian cancer treatment via primary debulking surgery (PDS) as well as neoadjuvant chemotherapy (NACT) followed by interval debulking surgery (IDS). Findings in Brief: Our findings suggest that Neoadjuvant chemotherapy (NACT) and interval debulking surgery (IDS) are alternative treatments for advanced-stage ovarian cancer patients where optimal debulking surgery is considered unfeasible, while some studies indicate that NACT/IDS offer similar oncological outcomes with fewer postoperative complications. The prediction of optimal debulking probability can be evaluated by CA-125 level ≥500 U/mL, performance status ≥2, suprarenal paraaortic or supradiaphragmatic nodes >1 cm, Porta hepatis disease, diffuse serosal bowel carcinomatosis, bowel mesenteric involvement or a PIV score ≥8 if a laparoscopy is performed. Conclusions: Regarding the management of advanced ovarian cancer patientswho receive neoadjuvant interval debulking surgery seems to be as efficacient as primary cytoreduction. The patients that are more eligible and could benefit from this treatment strategy should be specified through larger, double-blind randomized control trials.
Recruitment: A Problem of Entangled Temporal Parts
Authors: Caetano-Anollés Gustavo , Aziz M. Fayez , Mughal Fizza , Koç Ibrahim , Caetano-Anollés Kelsey , Caetano-Anollés Derek
Published: April 2022

Recruitment is a pervasive activity of life that is at the center of novelty generation and persistence. Without recruitment, novelties cannot spread and biological systems cannot maintain identity through time. Here we explore the problem of identity and change unfolding in space and time. We illustrate recruitment operating at different timescales with metabolic networks, protein domain makeup, the functionome, and the rise of viral ‘variants of concern’ during the coronavirus disease 2019 (COVID-19) pandemic. We define persistence within a framework of fluxes of matter-energy and information and signal processing in response to internal and external challenges. A ‘triangle of persistence’ describing reuse, innovation and stasis defines a useful polytope in a phase space of trade-offs between economy, flexibility and robustness. We illustrate how the concept of temporal parts embraced by the perdurantist school provides a processual 4-dimensional ‘worm’ view of biology that is historical and atemporal. This view is made explicit with chronologies and evolving networks inferred with phylogenomic methodologies. Exploring the origin and evolution of the ribosome reveals recruitment of helical segments and/or large fragments of interacting rRNA molecules in a unification process of accretion that is counteracted by diversification. A biphasic (bow-tie) theory of module generation models this frustrated dynamics. Finally, we further elaborate on a theory of entanglement that takes advantage of the dimensionality reduction offered by holographic principles to propose that short and long-distance interactions are responsible for the increasingly granular and tangled structure of biological systems.
Quarter-Century Explorations of Bioactive Polyphenols: Diverse Health Benefits
Authors: Chu Arthur J.
Published: April 2022

Polyphenols, members of phytochemical superfamily rich in vegetables and fruits, include flavonoids, non-flavonoids, and phenolic acids. Their biological effects includes classical antioxidation (e.g., radical-scavenging, metal chelating, NOX inhibition, attenuation on mitochondrial respiration, inhibition on xanthine oxidase, and upregulations on endogenous antioxidant enzymes), multiple regulations on cell signaling (e.g., AMPK activation, SirT1 activation, eNOS activation, FOXO activation, NFκB inactivation, PI3K/AkT inhibition, mTORC1 inhibition, PKC inhibition, MAPK inhibition, ERK inhibition, JAK/STAT inhibition, IKK/JNK inhibition, PDE inhibition, β-catenin inactivation, downregulation on TLR expression, ACE inhibition, adiponectin elevation, attenuated ET-1 production, and K+ channel activation), and many other actions (e.g., inhibition on α-glucosidase, anticoagulation, γ-secretase inhibition, monoamine oxidase inhibition, LPL upregulation, ANGPTL4 suppression, upregulation on paraoxonase 1, PAI-1 downregulation, tPA upregulation, immunoregulation, epigenetic modulation, and altered gut microbiota). Such multi- targeting and functions exhibiting antioxidative stress and antiinflammation as major pillars along with many other antagonisms could not only afford healthy polyphenols suitable supplements for promoting health, but also advance them to therapeutic applications. This review aims to translate diverse polyphenolic biochemical actions to clinical applications in fighting against non-communicable diseases such as CVD, cancer, diabetes, obesity, neurodegeneration, inflammatory diseases (e.g., IBD, IBS, NAFLD, etc.), AMD, allergy, and autoimmunity as well as communicable infection (e.g., bacteria, fungal, and viral).
Assessment of Antimicrobial Activity of Ethanolic and Aqueous Extracts of Aesculus hippocastanum L. (Horse Chestnut) Bark against Bacteria Isolated from Urine of Patients Diagnosed Positive to Urinary Tract Infections
Authors: Konstantinovitch Khar’kov Y. , Arsene Mbarga M.J. , Aliya Martynenkova V. , Viktorovna Podoprigora I. , Elena Volina G. , Azova Madina M. , Amira Ait A.
Published: April 2022

The search for new antimicrobials is essential to address the worldwide issue of antibiotic resistance. The present work aimed at assessing the antimicrobial activity of Aesculus hippocastanum L. (horse chestnut) bark against bacteria involved in urinary tract infections (UTIs). Bioactive compounds were extracted from A. hippocastanum bark using water and ethanol as solvents. The extracts were tested against 10 clinical uropathogenic strains including five Gram-positive and five Gram-negative bacteria. Staphylococcus aureus ATCC 6538 and Escherichia coli ATCC 25922 were used as reference bacteria. The susceptibility to antibiotics was assessed using the Kirby Bauer disc diffusion method and the antibacterial activity of the extracts was evaluated using the well diffusion method. The Minimum inhibitory concentration (MIC) and the minimum bactericidal concentrations (MBC) were asseded by the microdilution method. A. hippocastanum bark possessed a dry matter content of 65.73%. The aqueous extract (AE) and ethanolic extract (EE) showed a volume yield of 77.77% and 74.07% (v/v), and a mass yields of 13.4% and 24.3% (w/w) respectively. All the bacteria were susceptible to amoxiclav, imipenem and ceftriaxone but the clinical strains were resistant to at least one antibiotic. Kocuria rizophilia 1542 and Corynebacterium spp 1638 were the most resistant bacteria both with multidrug resistance index of 0.45. Except AE on Proteus Mirabilis 1543 and Enterococcus faecalis 5960 (0 mm), both AE and EE were active against all the microorganisms tested with inhibition diameters (mm) which ranged from 5.5–10.0 for AE and 8.0–14.5 for EE. The MICs of EEs varied from 1–4 mg/mL while those of AEs varied from 4–16 mg/mL. The ethanolic extracts (EE) were overall more active than the aqueous ones. The A. hippocastanum bark extracts had overall weak antibacterial activity (MIC ≥0.625 mg/mL) and bacteriostatic potential (MBC/MIC ≥16) on both Gram-positive and Gram-negative bacteria.
Androgen Receptor Activity Is Associated with Worse Survival in Glioblastoma
Authors: Fariña-Jerónimo Helga , de Vera Antonia , Medina Lilian , Plata-Bello Julio
Published: April 2022

Background: Some evidence about the role of the androgen receptor (AR) in pathogenesis of glioblastoma have been reported, but no study has focused on measuring the activity of the AR in GB. Therefore, the aim of this work is to study the role of AR and its activity as prognostic biomarkers in glioblastoma (GB). Methods: Molecular and clinical data from The Cancer Genome Atlas database were used. The AR-expression at protein-level was obtained from reversed phase protein array (RPPA) assays. The AR-activity was determined by calculating the AR-score, an index calculated by using the expression (at RNA-level) of 13 androgen-responsive-genes. Univariate and multivariate Cox-regression analyses were performed. Finally, a correlation analysis was conducted between protein expression data and the AR-score. Results: Two-hundred and thirty-three patients were included. RPPA data showed a mean AR abundance of 0.027(Statistical Deviation = 0.38) in GB. The univariate Cox-regression analysis showed that the AR-Score was associated with a worse prognosis (Hazard Ratio (HR) = 1.070) while the AR-expression did not show any relationship with survival (HR = 0.869). The association of the AR-score with worse overall survival (OS) was still significant in the multivariate analysis (HR = 1.054). The highest correlation coefficients between the AR-score and RPPA were identified in a group of proteins involved in apoptotic process regulation. Conclusions: GB patients with a high AR-activity present a worse prognosis in terms of OS. Thus, the activity of the AR may have a pathogenic role in GB. In this regard, the activation of the AR in GB may be associated with a dysregulation of apoptosis.
Review of Laboratory Methods to Determine HDL and LDL Subclasses and Their Clinical Importance
Authors: Chary Abdolreza , Hedayati Mehdi
Published: April 2022

Given the high prevalence of cardiovascular disease, accurate identification of methods for assessing lipoprotein subclasses, mainly low-density lipoprotein (LDL) and high-density lipoprotein (HDL) subfractions, can play an essential role in predicting the incidence of cardiovascular disease such as heart attack. LDL and HDL subclasses differ in size, surface charge, lipid and protein compositions, and biological role. There is no “gold standard” method for measuring the LDL and HDL subclasses or standardizing the different methods used to measure their subfractions. Over the past decades, various techniques have been introduced to evaluate and measure subclasses of these two lipoproteins, each with its own advantages and disadvantages. Development of laboratory methods that accurately HDL and LDL function must be developed and validated to high-throughput for clinical usage. In this review study, we tried to examine different methods of evaluating various subclasses of LDL and HDL by mentioning the strengths and weaknesses of each.
Exercise Training after Myocardial Infarction Attenuates Dysfunctional Ventricular Remodeling and Promotes Cardiac Recovery
Authors: Liu Shuqing , Meng Xinxiu , Li Guoping , Gokulnath Priyanka , Wang Jing , Xiao Junjie
Published: April 2022

Recent evidences have shown that exercise training not only plays a necessary role in maintaining cardiac homeostasis, but also promotes cardiac repair after myocardial infarction. Post-myocardial infarction, exercise training has been observed to effectively increase the maximum cardiac output, and protect myocardial cells against necrosis and apoptosis, thus leading to an improved quality of life of myocardial infarction patients. In fact, exercise training has received more attention as an adjunct therapeutic strategy for both treatment and prevention of myocardial infarction. This review summarizes the experimental evidence of the effects of exercise training in ventricular remodeling after myocardial infarction, and tries to provide theoretical basis along with suitable references for the exercise prescription aimed at prevention and therapy of myocardial infarction.
Service Quality Improvement Effort (An Indonesian Restaurant Empirical Fact)
Authors: Imanuel Gabriella , Wirawan Christina
Published: April 2022

Customer satisfaction is very important for a business because it will determine the arrival and purchase of customers. One of the determinants of customers satisfaction is service quality. A business needs to pay attention to service quality so that it can always provide satisfaction to customers. As a case, this article studied Resto XYZ. This restaurant is experiencing a decline in revenue. The cause of this decline in revenue is the lack of customer satisfaction which is indicated by the number of customer complaints. This study aims to measure customer satisfaction and then provide suggestions to improve Resto XYZ’s service quality using SERVQUAL method popularized by Parasuraman. We made modifications for gaps measurement from Parasuraman's model. Data collection was carried out by quantitative and qualitative methods. As a result,  some variables are found unsatisfactory for customers. Mostly the cause of the customers' dissatisfaction is a lack of management knowledge about customers' expectations. For this reason, this study provides suggestions for management to keep in relation with customers and create surveys to gain information about customers' expectations. Other suggestions related improve photos in the menu, managing employees' work to shorten the service time, tightening the health protocol, redecorating the dining area, and providing adequate parking space.
Application of Ranked Position Weight and Region Approach Method in Overcoming Bottlenecks in Garment Industry
Authors: Chang Hsueh-Lin , Silitonga Riana Magdalen , Zelita Yennie , Adilah Muna , Jou Yung-Tsan
Published: April 2022

Batik Delapan Satu is a manufacturing company specializing in the garment field. There is a bottleneck line at the production that can cause production to be hampered. This bottleneck line occurs at the trimming workstation, so imbalanced work flow. Then, we use Line balancing with the Ranked Positional Weight method and the Region Approach method to solve this bottleneck line problem. Using the Ranked Positional Weight method and the Region Approach method will produce line efficiency, balance delay, idle time, and smoothness index. Using the Ranked Positional Weight method and the Region Approach method will increase efficiency line from the condition of the company start 52.02% up to 73.82%. Besides that, it can reduce five-station work, which was seven-station work before, and reduce the level of idle time in the company, they used to take 1057.83 seconds, but now they only take 427.92 seconds.
A Case Study of Ergonomics Prevention Program in a Machine Manufacture Industry
Authors: Wang Pei-Chia , Yang Cheng-Chun , Huang Yen-Chun , Cheng Yu-Sen
Published: April 2022

Musculoskeletal Disorders (MSDs) is the most potential risks in human production and economic systems. In this research, ergonomics guidelines and enacted relevant regulations announced by other countries to effectively facilitate ergonomics prevention programs were discussed. A machine manufacture industry as a case study has been ergonomically evaluated by Musculoskeletal Disorders Checklist (MSDs) and Nordic Musculoskeletal Questionnaire (NMQ), which was used to recognize the dominating risk factors. According to the result of observation and preliminary assessment, low back pain related to the high frequency of manual material handling tasks was the critical issue in this case study. The conclusion revealed that the proposed improvement such as engineering redesign, training, health management, and administration, would be implemented into the main axle assembly area, customer service department, and Z-axis assembly area. The further improvement interventions would help organization to carry out the ergonomics prevention program.
“Republic of literature” on the banks of the Neva: from the history of public self-awareness of the Russian nobility in the last third of the 18th century (according to the letters of M.N. Muravyov to his father and sister, 1777—1778)
Authors: Kunts Evgeny
Published: April 2022

In the second half of the 18th century, Russian nobles showed attention to the problems of personality, morality, human dignity, culture, art, science. In the article, based on the correspondence of M.N. Muravyov with his relatives, the features of the system of interpersonal communications in the capital’s literary environment of the second half of the 70s of the 18th century are considered. It is concluded that the literary community served as an important channel for the dissemination of the ideas of the Enlightenment.
Makalah Aspek Permodalan Koperasi
Authors: Nurhayati
Published: April 2022

Asset dalam perusahaan yang berwujud uang kas merupakan suatu variabel yang sangat penting bagi perusahaan. Uang kas ini menduduki posisi sentral, karena seluruh kegiatan yang ada didalam perusahaan akan terkait dengan uang kas.Modal utama mendirikan koperasi adalah diwujudkan dalam bentuk simpanan anggota. Meskipun bukan segala-galanya, modal merupakan faktor produksi yang penting bagi lingkup kegiatan ekonomi. Tanpa adanya kecukupan modal, terbukti tidak sedikit kegiatan ekonomi/bisnis justru mengalami hambatan. Demikian halnya dengan koperasi, kecukupan modal merupakan salah satu persyaratan penting untuk mendapatkan status badan hukum.
resume ekonomi 3
Authors: AR ASHRA
Published: April 2022

penawaran adalah banyaknya barang atau jasa yang tersedia dan ditawarkan oleh produsen kepada konsumen
Aspek Permodalan Koperasi
Authors: Ilman Afnan Nur
Published: April 2022

Sebagaimana Kоperasi, seperti bisnis lainnya, memerlukan alat untuk mengukur kinerja keuangan mereka agar tetap bertahan. Alat ini juga dapat digunakan sebagai bahan evaluasi bagi pelanggan jasa kоperasi, serta bagi manajemen, investоr, dan pihak terkait lainnya.
Ilmu komunikasi dalam al-Quran
Authors: Bausin Laksmi
Published: April 2022

Tujuan dari penelitian ini adalah untuk mengetahui konsep komunikasi dalam kesucianAlquran. Penelitian ini merupakan penelitian kualitatif yang menerapkan teologi sosialmendekati. Hasil penelitian ini mengungkapkan bahwa Al-Qur'an menggambarkan konsep tersebutkomunikasi menjadi beberapa bentuk. Oleh karena itu, para cendekiawan muslim mengklaim bahwa adaAda delapan bentuk komunikasi yang disebutkan dalam Al-Qur'an, yaitu qaulkarim, qaul ma'ruf, qaul layyin, qaul adzim, qaul balig, qaul maisur, qaul tsaqil,dan qaul sadid. Lebih jauh, Al-Qur'an menginformasikan bahwa dalam komunikasi, seseorang perlu untukmenganggap komunikan untuk mencapai suatu tujuan yang disengaja. penentuan dariBentuk komunikasi yang dipilih untuk digunakan telah ditawarkan dalam Al-Qur'an sebagai cara alternatif dalamTujuan dari penelitian ini adalah untuk mengetahui konsep komunikasi dalam kesucianAlquran. Penelitian ini merupakan penelitian kualitatif yang menerapkan teologi sosial.
resume ekonomi 2
Authors: AR ASHRA
Published: April 2022

permintaan merupakan hubungan antara jumlah permintaan dengan harga
Hubungan dan Pembagian Kerja Dalam Pengelolaan Koperasi
Authors: Ilman Afnan Nur
Published: April 2022

Untuk mengidentifikasi kelemahan-kelemahan dalam manajemen kоperasi secara keseluruhan dan untuk mengembangkan alternatif, pendekatan manajemen yang lebih tepat, diperlukan pemeriksaan menyeluruh terhadap seluruh prоses manajemen, masalah yang dihadapi, dan tujuan yang ingin dicapai sejauh ini dan di masa depan.
KURVA KEPUASAN SAMA
Authors: farid
Published: April 2022

catatan tugas resume ekonomi mikro tentang kurva kepuasan sama
resume utility
Authors: Irtiy
Published: April 2022

nilai guna atau utilitas merupakan kepuasan dan kenikmatan yang diperoleh seseorang dalam mengkonsumsi barang dan jasa
Informasi Al Qur'an tentang janin dan pertumbuhannya
Authors: golonda Lisa
Published: April 2022

Artikel ini membahasa tentang Informasi Al Qur'an tentang janin dan pertumbuhannya
menganalisis industri dan para pesaing
Authors: Ahmad Rahmayani
Published: April 2022

ABSTRAKMakalah ini berjudul menganalisis industry dan para pesaing. Dalam makalah ini mengkaji tentang tata cara mengidentifikasi pesaing dan strategi pesaing, tujuan dari pesaing, dan tata cara memperkirakan kekuatan dan kelemahan pesaing. Persaingan bisnis merupakan hal yang wajar di dunia perindustrian. Setiap perusahaan berlomba menawarkan berbagai macam keunggulan dan manfaat produk yang dipasarkannya dengan tujuan untuk memperoleh keuntungan. Dalam menghadapi persaingan tersebut, manajemen perusahaan harus cerdik dalam menciptakan ikatan tertentu antara produk yang ditawarkannya dengan konsumen. Tujuan di buatnya makalah ini tentunya ialah memenuhi tugas dari mata kuliah manajemen pemasaran perbankan syariah selain itu ialah untuk lebih memahami bagaimana proses penganalisaan industry dan para pesaing.
Sistem Informasi Manajement Pabrik pakaian
Authors: Aprilsyah Muhammad
Published: April 2022

Proposal ini berisi tentang pengajuan dan penjelasan seputar Digital Marketing yang berkaitan dengan Pabrik Pakaian
tsunami dan likuivikasi dalam al-quran
Authors: bau Siti nuranisa
Published: April 2022

Tujuan penelitian ini adalah untuk menganalisis kesesuaian bencana likuifaksi dalam perspektif Al-Qur’an dan Sains, karena para pakar ilmu bumi menyatakan bahwa bumi ini terbagi menjadi lempeng-lempeng (plate) tektonik, yang saling bergerak dengan kecepatan 5-10 cm/tahun. Di Indonesia terdapat 3 lempeng besar yang saling berinteraksi, yaitu lempeng Eurasia, Indo-Australia dan Pasifik. Interaksi ini menghasilkan serangkaian gunung api aktif yang dikenal dengan “Ring of Fire” (cincin api). Peristiwa ini menyebabkan gempa bumi yang memiliki kekuatan guncangan yang sangat dahsyat, sehingga menyebabkan perubahan struktur tanah. Kondisi tanah yang padat menjadi lunak sehingga tidak mampu menahan beban benda yang berada di atas permukaan tanah tersebut, oleh para ilmuwan sains peristiwa ini dinamakan likuifaksi.Beberapa kajian pustaka yang ditemukan, sebagian besar membahas bencana likuifaksi secara umum atau dari sisi sains, sedangkan dalam disertasi ini penulis menganalisis dan mendeskripsikan bencana likuifaksi dalam kajian Al-Qur’an. Kajian Al-Qur’an inilah yang menjadi perbedaan dalam penelitian yang dilakukan oleh peneliti-peneliti sebelumnya.
Negara Kesatuan atau Unitaris
Authors: Jainap
Published: April 2022

Makalah ini memuat tentang bentuk Negara, yaitu Negara kesatuan atau unitaris, Dalam makalah ini juga di jelaskan tentang pengertian atau definisi dari Negara kesatuan, Negara kesatuan adalah sebagai negara yang diatur secara konstitusional sebagai entitas independen dengan legislatif yang dibuat berdasarkan konstitusi. Negara kesatuan atau unitaris ini juga mempunyai konsep, ciri ciri, dan macam macam sistem Negara Kesatuan dan Unitaris, macam macam sistem Negara kesattuan ini ada dua yaitu sentralisasi dan desentralisasi.
Aspek Permodalan Koperasi
Authors: Aryam
Published: April 2022

Kontribusi Usaha Mikro, Kecil, dan Menengah (UMKM) bagi pembangunan perekonomian Indonesia tidak dapat dikecilkan. Menurut Susilo (1996), UMKM memiliki posisi yang penting dalam perekonomian nasional dalam hal kontribusinya pada penyerapan tenaga kerja, Pendapatan Domestik Bruto (PDB), serta fleksibilitas dan ketangguhannya dalam menghadapi krisis ekonomi yang berkepanjangan
Teori Nilai Guna Pada Ekonomi Mikro
Authors: Aisyah Nuraisyah
Published: April 2022

Utility atau nilai guna sering digunakan sebagai istilah untuk menjelaskan mengenai suatu manfaat barang atau komoditas tertentu. Pada teori keseimbangan, diketahui bahwa teori keseimbangan menggambarkan antara kesesuaian antara permintaan dan penawaran. Permintaan timbul karena konsumen memerlukan manfaat dari komoditas yang diminta. Manfaat inilah yang dikenal dengan istilah utilitas (utility).
Aspek permodalan koperasi
Authors: widiyanti
Published: April 2022

Modal Koperasi adalah Sejumlah dana yang akan digunakan untuk melakukan kegiatan-kegiatan atau usaha-usaha dalam koperasi.
Puasa sebagai Terapi Psikosomatik
Authors: Qosim Nanang
Published: April 2022

Ibadah puasa di bulan Ramadan ini termasuk salah satu jalan terapi untuk menyembuhkan Psikosomatik. Sebagaimana dikutip dari Usman Najati (1995:207) yang menyatakan tentang pentingnya agama dalam mengatasi keresahan, kecemasan dan gangguan jiwa. Keimanan kepada Tuhan merupakan kekuatan luar biasa yang membekali manusia dalam menanggung beratnya beban kehidupan, menghilangkanya dari keresahan yang menimpa manusia di zaman modern seperti sekarang ini. Lebih lanjut dia mengutip pendapat William James seorang filosof dari ahli ilmu jiwa terkemuka yang menyatakan bahwa terapi terbaik bagi keresahan ialah keimanan kepada Tuhan. Sebab individu yang benar-benar relegius akan terhindar dari segala keresahan dan gangguan jiwa. Dan semua ahli psikoterapi setuju dan sependapat bahwa keresahan merupakan penyebab utama timbulnya timbulnya gangguan jiwa. Keimanan kepada Tuhan, apabila di tanamkan pada individu sedini mungkin akan memberinya pelindung dan penangkal dari berbagai gangguan kejiwaan. Oleh karena itu puasa ini merupakan pendidikan dan pelurusan jiwa serta penyembuhan dari berbagai gangguan jiwa dan tubuh. Karena selama puasa, dengan mencegah makan, minum dan hubungan seksual sejak sebelum fajar dampai terbenaam matahri, merupakan latihan dan menundukkan hawa nafsu.
GAMBARAN UMUM PERBANKAN SYARIAH DI INDONESIA
Authors: Agnusia Nur Adillah
Published: April 2022

Sektor perbankan menempati posisi sangat strategis dalam menjembatani kebutuhan modal kerja dan investasi di sektor riil dengan pemilik dana. Fungsi utama sektor perbankan dalam infrastruktur kebijakan makro ekonomi memang diarahkan dalam konteks bagaimana menjadikan uang efektif untuk meningkatkan nilai tambah perbankan alternatif tidak terlepas dari akibat dari terjadinya krisis ekonomi yang awalnya dipandang sebagai krisis Islamic Banking atau juga disebut dengan Interest Free Banking. Peristilahan dengan menggunakan kata Islamic tidak dapat dilepaskan dari asal-usul sistem perbankan kelompok ekonom dan praktisi perbankan muslim yang berupaya mengakomodasi desakan dari berbagai pihak yang menginginkan agar tersedia jasa transaksi keuangan yang dilaksanakan sejalan dengan nilai moral dan prinsip Utamanya adalah berkaitan dengan pelarangan praktek riba, kegiatan maisir (spekulasi), dan gharar (ketidakjelasan)
Aspek permodalan koperasi
Authors: Rezky Sri
Published: April 2022

Keperhasilan koperasi dalam melaksanakan perannya sebagai badan usaha sangat tergantung pada kemampuan koperasi menghimpun dan menanam modalnya dengan pemupukan berbagaj sumber keuntungan dan banyaknya jumlah anggota.
FENOMENA IT’TIFAK DAN IKHTILAF DALAM AL’QURAN Nurbaisa Putri Pangajo, Jurusan Pendidikan Guru Madrasah Ibtidaiyah Email ; (nurbaisa2018@gmail.com)
Authors: pangajo Nurbaisa putri
Published: April 2022

Perbedaan pendapat dalam penafsiran terhadap ayat hukum dapat menimbulkan kesan adanya disharmoni antara satu sama lain ajaran Alquran. Padahal ayat 82 Surah al-Nisa menegaskan bahwa tidak ada kontradiksi dalam Alquran. Namun persoalan ini tidak terakomodir dalam kajian fikih karena perbedaan dilihat sebagai masalah furukiyah saja. Padahal tidak sedikit perbedaan itu terjadi pada isu-isu fundamental ajaran Islam. Sayangnya hal ini juga tidak tertangani oleh disiplin ilmu tafsir karena orientasinya yang terfokus pada penemuan makna. Oleh karena itu, tulisan ini menawarkan sebuah kerangka teoritik fiqh al-ikhtilāf agar penafsiran tidak melihat perbedaan yang terdapat dalam ayat hukum sebagai kontradiksi tetapi melihatnya sebagai keragaman (al-ta‘addud al-tanawwu‘). Memadukan metode deduktif interpretif dan metode analisis kritis, tulisan ini melakukan kajian terhadap landasan filosofis tafsir ayat hukum. Landasan filosofis itu mencakup asumsi dasar, paradigma dan kerangka teori. Selanjutnya, menggunakan pendekatan filsafat, kajian ini sampai pada simpulan bahwa kerangka teoretik fiqh al-ikhtilāf tepat digunakan untuk menyikapi perbedaan penafsiran dalam tafsir ayat hukum.