bluuebunny/crossref_metadata_2025 huggingface dataset:
Modelling of emotional exhaustion role on workplace ostracism: A cross-sectional study on Sepah Bank branches in northern provinces of Iran
Authors: Yazarloo Firroz , Shojaei Samere , Azma Fereydoon , Mostaghimi Mahmood Reza
Published: July 2021

Background and aims: Workplace ostracism is the degree to which a person feels ignored by others in the workplace. This study aimed to evaluate the role of emotional exhaustion on workplace ostracism in Sepah Bank branches in Northern provinces of Iran. Methods: The present cross-sectional study was conducted as a field survey. The statistical population included 1472 employees of Sepah Bank branches in Northern provinces of Iran. According to the Cochran’s sample size formula, 306 individuals were identified as the research sample. The research tool was a 49-item researcher-made questionnaire, the validity of which was confirmed after reviewing the experts’ opinions. The reliability of the questionnaire was 0.82 for emotional exhaustion and 0.85 for workplace ostracism. In this study, the structural equation method was used. Data analysis was performed using SPSS and LISREL. Results: The results of the study showed that the mean of emotional exhaustion and workplace ostracism was 2.31 and 2.57, indicating an undesirable status of these variables. In addition, emotional exhaustion had a significant effect on the workplace ostracism (P=0.001; effect=0.22; t=3.25). Conclusion: Given the serious impact of emotional exhaustion on workplace ostracism, Sepah Bank should plan programs to reduce emotional exhaustion.
Evaluation of antidepressant effects of hydroalcoholic extract of Kelussia odoratissima Mozaffarian in male mice
Authors: Asgharzadeh Najmeh , Hajihasani Fatemeh , Lorigooini Zahra , Mardani Marzieh , Amini Khoei Hossein , Moradi Mohamadtaghi , Shahrani Korrani Mehrdad
Published: July 2021

Background and aims: Depression is one of the most common psychiatric disorders with serious impacts on individuals, and is often associated with physiological symptoms. In this study, we investigated the antidepressant effects of Kelussia odoratissima Mozaffarian extract in male mice. Methods: A total of 56 male mice (weight: 25-35 g; age: 6-8 weeks) were used. K. odoratissima Mozaffarian hydroalcoholic extract was prepared by maceration method. The forced swim test, open field test, and splash test were used to investigate the antidepressant effects. The mice were assigned into eight equal groups (n=7 each) as follows: receiving 25, 50, 75, and 100 mg/kg of K. odoratissima Mozaffarian extract; receiving 5 mg/kg reserpine; receiving 5 mg/kg reserpine along with 20 mg fluoxetine; and normal saline. All injections were done intraperitoneally for one week before the test. Malondialdehyde (MDA) levels and antioxidant capacity of serum and brain were also measured in all groups. Statistical analysis was performed by one-way ANOVA and Tukey’s test. Results: Extract of K. odoratissima Mozaffarian significantly decreased the immobility time in forced swim test (P<0.001). The extract also significantly increased splash time and elapsed time in the open field test, which was statistically significant compared with reserpinated mice (P<0.001). Reserpine increased MDA levels and decreased the antioxidant capacity of serum and brain, whereas hydroalcoholic extract of K. odoratissima decreased MDA dose-dependently and increased antioxidant capacity (P<0.001). Conclusion: The results of this study showed that hydroalcoholic extract of K. odoratissima has antidepressant effects, but further studies are necessary to investigate the involved mechanisms.
Histological modifications of the rat prostate following oral administration of silver nanoparticles
Authors: Sheida Fateme , Hamzehpour Manijeh , Sohrabi Maryam , Alizadeh Zohreh
Published: July 2021

Background and aims: Recently, silver nanoparticles (AgNPs) have received much attention for their possible usage in various fields. This study examined the effect of AgNPs on the histopathological changes in the prostate of rats. Methods: In this study, 40 male adult Wistar rats were divided into five equal groups (n=8 in each group). AgNPs were given orally to the four experimental groups at doses of 30, 125, 300, and 700 mg/kg for 28 consecutive days. The control group received deionized water. After performing hematoxylin and eosin (H & E) staining and Masson’s trichrome staining, the histological changes in the prostate of rats were evaluated. Results: Histological evaluation showed that the acinar epithelial height and alveolar folds decreased, but vacuoles in the epithelial cells and accumulation of blood vessel increased in the groups treated with AgNPs at doses of 30 and 125 mg/kg. The collagen content also increased significantly in these groups (30 mg/kg: P=0.03 and 125 mg/kg: P=0.002). Furthermore, the groups treated with AgNPs at doses of 300 and 700 mg/kg showed relative normalization acini and epithelial lining and the amount of their content. Conclusion: According to the results of current study, oral administration of AgNPs for 28 days had effects on prostate, indicating the toxicity of AgNPs.
Comparison between the tie-over and Karydakis procedure in chronic sacrococcygeal pilonidal sinus
Authors: Moazeni Bistgani Mohammad
Published: July 2021

Background and Aims: Pilonidal sinus in the sacrococcygeal region is a disease with high postoperative morbidity and discomfort for the patient. Although there are various therapeutic modalities to manage these patients, Controversy for choosing the best surgical technique in order to decrease the recurrence rate, patient discomfort, and Duration of disability after surgery still exists. Therefore, the objective of the present study was to compare results reached from two methods of surgery, tie-over procedure (TOP) and Karydakis procedure(KP) for the treatment of sacrococcygeal pilonidal sinus. Methods: In this study, 70 patients with a diagnosis of pilonidal sinus disease treated randomly with surgical excision and TOP or KP, in two 35 patients group, in the educational hospital by the same surgeon, between 2009 and 2010, and followed up until December 2019. Results: Achieved data after excision of sacrococcygeal pilonidal sinus indicate that primary closure of the wound by tie-over sutures have a better result than KP in order of Pain sore during the first month after surgery (P< 0.001), Duration of disability (P <0.001), wound repair time (P <0.001) and Patient satisfaction(P=0.019). Conclusion: Overall, these results show the TOP instead of KP, because higher acceptance results may be an alternative better for the treatment of chronic pilonidal sinus for the patients who have surgery scheduled for them.
Comparing coping styles, personality traits, and resiliency in multiple sclerosis patients
Authors: Katani Amir Mahdi , Mohammadi Shahnaz , Davoodi Zahra , Shahmoradi Somaye
Published: July 2021

Background and aims: Multiple sclerosis (MS) is a common neurological disorder with complex etiology, which is highly affected by psychological factors. These factors should to be identified to help patients with MS (PwMS). This study aimed to compare coping styles, personality traits, and resiliency in PwMS and healthy subjects. Methods: In this case-control study, we selected 75 PwMS from the members of Tehran MS Society in 2016 as case group and 75 healthy subjects as control group. To collect data, we used the Ways of Coping Questionnaire (WOCQ), Big Five Factor Inventory–Revised, and Conner-Davidson Resilience Scale (CD-RISC). Multivariate analysis of variance (MANOVA) and independent T-Test were used to analyze the data. Results: The results indicated that PwMS use emotion-focused coping styles more often (44.53±9.13, P=0.008) and problem-focused coping styles less often (39.84±5.79, P=0.001) compared to control group. Also, they showed higher scores in neuroticism (32.10±4.80, P=0.001) and lower scores in extraversion and conscientiousness (27.46±7.12, P=0.005 and 32.98+±5.72, P=0.008, respectively). The resiliency levels in these patients were also lower than healthy subjects (68.13±13.90, P=0.021). Conclusion: Our findings indicated that PwMS are more likely to use emotional coping strategies in stressful situations compared to healthy individuals. Moreover, data confirmed that a maladaptive personality configuration, which is specified by high neuroticism, along with low extraversion, conscientiousness, and agreeableness are somehow related to MS.
Comparison of ADAM17 gene expression level in acute lymphoblastic leukemia patients
Authors: Karimi Shakiba , Zia Jahromi Noosha
Published: July 2021

Background and aims: In acute lymphoblastic leukemia (ALL), large numbers of stem cells become lymphoblasts or lymphocytes. Among the genetic factors influencing cancer is the ADAM (a disintegrin and metalloprotease) gene family. Due to the important role of this family in cancer, this study aimed to compare the expression level of ADAM17 gene in patients with ALL and healthy individuals. Material and Methods: In this case-control study, 40 venous blood samples were taken from ALL patients referred to Omid hospital in Isfahan, Iran. Also, 40 venous blood samples were taken from healthy individuals in vitro. Lymphocyte isolation was performed using a ficol and cell RNA was isolated using an RNX-Plus kit. It was then converted to cDNA using the Yekta Tajhiz Azma kit. Finally, reverse transcription-polymerase chain reaction (RT-PCR) technique was used to evaluate the relative expression of ADAM17 gene in blood samples of healthy individuals and patients with leukemia, and the ratio was measured with the reference GAPDH gene. SPSS software version 22 and t test were used to analyze the data. Results: The expression level of ADAM17 gene in patients with ALL compared to the control group showed a significant increase, which was statistically significant (P=0.043). Conclusion: It seems that increasing the expression of ADAM17 gene in people with ALL is a suitable biomarker to diagnose this disease.
Evaluation of isolation method in remaining of differentiation potential of perivascular human umbilical cord mesenchymal stem cells toward male germ cell-like
Authors: Shojaeian Ali , Mehri-Ghahfarrokhi Ameneh , Rahmati-Dehkordi Shima , Banitalebi-Dehkordi Mehdi
Published: July 2021

Background and aims: Infertility is one of the most common problems among couples. Generation of male germ cells from adult stem cells is a current promising priority of researchers. This study aimed to investigate the potential of human umbilical cord mesenchymal stem cells (hUMSCs) on the expression of male germ cell markers after isolating by this method. Methods: The hUMSCs was incubated with retinoic acid, testosterone, and conditioned medium (prepared from testicular cell cultures of 7-day-old mice) during 3 days. The bands were visualized and densitometry was accomplished using LI-COR Biosciences software. Results: The high expression levels of C-KIT, DAZL, PIWIL2, and DDX4 in mRNA and protein levels were observed in treated hUMSCs. Conclusion: Results of reverse transcription polymerase chain reaction (RT-PCR) and western blotting showed that method of isolation had no adverse effects on differentiation potential of hUMSCs.
Comparing the Effect of Two Low-dose and High-dose Four-drug Regimens of Furazolidone in Eradicating Helicobacter Pylori
Authors: Seyedmajidi Mohammad Reza , Hosseini Seyed Ashkan , Vafaeimanesh Jamshid
Published: July 2021

BACKGROUND Antibiotic resistance is a major cause of Helicobacter pylori (H. pylori) treatment failures. The increased resistance to clarithromycin and metronidazole has reduced the ability of this therapeutic regimen and prompted researchers to look for other drugs. One of the antibiotics of interest in this regard is furazolidone because of its low drug resistance. The aim of this study is compare two-drug regimens including low-dose and high-dose furazolidone in the treatment of H. pylori. METHODS This study is a clinical trial in which the studied subjects were categorized into two groups. The first group underwent treatment with amoxicillin 1000 mg-BD, furazolidone 100 mg-BD, omeprazole 20 mg-BD, and bismuth subcitrate 240 mg-BD for two weeks (low-dose OFAB). The second group received furazolidone 200 mg-BD (high-dose OFAB). Then eight weeks after completion of the treatment, they were examined in terms of eradication via the UBT test. RESULTS 85 participants completed the study in each group. The response to treatment was 76% and 83% in the low and high-dose groups, respectively, based on intention to treat analysis. Based on per protocol analysis the response to treatment was 78% and 84%, respectively, if excluded patients had completed their protocol and had response to treatment, and 72% and 79%, respectively, if excluded patients had completed their protocol and did not have response to treatment (p = 0.298). In the low-dose and high-dose groups, 16.5% and 24.7% of the participants suffered the complications of treatment with furazolidone (p = 0.18), respectively. Three patients in the high-dose group and one in the low-dose group did not complete the treatment because of the medication’s bad taste (p = 0.03). CONCLUSION Low doses of furazolidone had a comparable therapeutic effect compared with high doses, but patients experienced significantly lower levels of bad taste, which was a major cause of reluctance to continue treatment. Therefore, we think four-drug low-dose furazolidone treatment is a good choice in eradicating H. pylori.
Use of Over-the-Scope Clip as First Choice to Treat Gastric Dieulafoy Lesions
Authors: Onmez Attila , Torun Serkan
Published: July 2021

Dieulafoy lesion is a rarely seen, superficial vascular lesion of the gastric mucosa that can lead to severe and recurrent bleeding which can be life-threatening. It is characterized by massive hemorrhages that can occur as a result of protrusion of a large artery from a submucosal defect. Endoscopic injection and mechanical and thermal methods are frequently used in traditional treatment. Herein, we presented a 61-year-old women who was admitted with upper gastrointestinal hemorrhage owing to Dieulafoy lesion who was successfully treated with over-the-scope clip as the first choice of treatment.
The effect of extract of Dunaliella salina L. on expression of anti-apoptotic BCL2 in Hela cell line
Authors: Lajavardi Mahdie- Sadat , Kavousi Mahsa
Published: July 2021

Background: After breast cancer, cervix neoplasm is the most common disease among young women. Nowadays, natural substances are used in the treatment of diseases, because of the known side effects of the chemical drugs. Dunaliella is a green alga that lives in the saltwater lakes of Iran and is abundant in antioxidant substances. This paper aimed to study the effect of Dunaliella extract on the expression of the anti-apoptotic BCL-2 gene in Hela cell line. Expression of this gene is increased during cancer. It is expected that gene expression will be reduced if the alga extract is effective. Methods: Hela was prepared from the Center for Genetic and Biological Reserves of Iran and cultured. After culture, cells were divided into two treatment and control groups. Different concentrations of algae extract were applied to the treatment group for 48 hours. Then its toxicity was measured using MTT assay and IC50 was determined. RNA was extracted from cells of two groups, to determine the relative amount of gene expression at a concentration of IC50. Then Real-time PCR was used. Results: The result of Real-time PCR showed that the relative expression of BCL-2, in treatment group cells that were affected by algae extract, was four times lower than the control group. Since the P-value is less than 0.05 (P-value = 0), this decrease is significant. Conclusion: After 48 hours, at a concentration of IC50 of algae extract, the relative expression of BCL-2 was four times lower than control group.
The effect of six weeks of vestibular stimulation training on the static and dynamic balance of children with hearing impairment
Authors: MousaviZadeh Vahideh Sadat , Daneshmandi Hassan , Sedaghati Parisa
Published: July 2021

Background: The motion of the deaf is often inhospitable and without rhythm, and the imbalance in functionality is the root cause of such a phenomenon. Therefore, the purpose of this study was to investigate the effect of Vestibular Stimulation Training on functional balance in children hearing impaired. Methods: This study was a semi-experimental design with pre-test and post-test design. The statistical population included the children of preschool and pre-school children of Ghotbzadeh in Rasht city. Among the statistical population, 24 were available and randomly divided into two groups: control (12) and experimental (12 people). Experimental group performed weekly three sessions of Vestibular stimulation exercises for six weeks. Before and after the training period, the static and dynamic equilibrium was measured by the Bronkins-Oseretsky sub-test and the functional equilibrium was measured by the Timed Up and Go. Results: There was a significant difference on the static equilibrium (p = 0.001), dynamic (p = 0.02) and functional (p = 0.001) in the experimental group after the intervention period. Conclusion: The assessment of the balance of hearing impaired children showed improvement in their motor abilities after six weeks of Vestibular stimulation exercises Considering the results of this study and the importance of balance for hearing impaired, it is suggested that coaches, parents and authorities of special centers and schools use these exercises because of their simplicity, cheapness and side effects to improve the balance in the program for the rehabilitation of hearing impaired children.
Paroxetine effect on expression of TLR2 and TLR4 genes in PBMCs of mentally normal individuals
Authors: Ganjalishahi Fatemeh , Hemmatpur Anahid , Dehghan manshadi Mahdi , Hadi nedoushan Hossein , Karimollah Alireza
Published: July 2021

Background: Paroxetine is one of the well-known antidepressants. Recent studies have focused on paroxetine’s probable immuno-modulatory effects, since findings have indicated inflammation’s role in the pathophysiology of depression. Therefore, in the present study, TLR2 and TLR4 mRNA genes expression was assessed in paroxetine-treated peripheral blood mononuclear cells (PBMCs). Methods: Venous blood samples were drawn from five healthy men (20-40 years old). Peripheral blood mononuclear cells (PBMCs) were isolated from samples and were cultured. After the first incubation for 24h, phytohemagglutinin plus lipopolysaccharide were added to the cells and then were incubated for 24h. Thereafter, cells were treated with different concentrations of paroxetine in the presence or absence of inhibitors of 5-HT2 and 5-HT7 receptors. After incubation for 48h, RNA was extracted and cDNA was synthesized. Using the real-Time PCR technique, TLR2 and TLR4 genes mRNA expression were evaluated. Statistical analysis of data were carried out using GraphPad Prism 7. Results: TLR2 and TLR4 mRNA expression were significantly increased in response to paroxetine at all concentrations. Furthermore, the co-culture of cells with the drug and the 5-HT2R and 5HT7R inhibitor simultaneously revealed that paroxetine’s immuno-modulatory effects viaTLR2 are dependent on serotonin, while it is independent of serotonin in the case of TLR4. Conclusion: Considering paroxetine’s effect in modulating immune responses via increasing TLR2 and TLR4 expression, paroxetine could have therapeutic potentials in diseases with a deficiency in these receptors.
Oral acetaminophen administration for patent ductus arteriosus (PDA) closure in preterm neonates
Authors: Samadi Mahmood , Nabaee Zahra , Mostafagharebaghi Manizheh , Mahalei Majid , Sheykhsaran Elham , Mirnia Kayvan
Published: July 2021

Background: Patent Ductus Arteriosus (PDA) is considered one of the most prevalent types of congenital heart disease. The closure of the ductus arteriosus physiologically occurs at the first 48-72 hours after the birth in healthy term infants. Different causes can result in the pathological opening of ductus arteriosus. This study aims to investigate the effect of oral acetaminophen on the closure of PDA in preterm neonates. Methods: The present study is a trial without control. Forty-five preterm neonates with a gestational age of <32 weeks were studied. Acetaminophen was orally administered with a dose of 10mg/kg every 6 hours for three days. Closure of ductus arteriosus was considered as the success of treatment. Data were analyzed using SPSS 15. Data were reported as )frequency-percent) and mean ± SD. To evaluate the normal distribution of data, we used a Kolmogorov-Smirnov test. Statistical significance was defined as P<0.05. Results: The study population consisted of 20 male and 25 female infants with the mean gestational age of 28.95 ± 1.66 weeks. Cesarean-born infants and vaginal-born infants consisted 17.8% and 82.2% of the study population, respectively. The proportion of PDA closure after administration of oralacetaminophen was 82.3%. Conclusion: The current study indicates that oral acetaminophen is highly effective in closing PDA. Considering its trivial side effects, it has the potency to be a convenient option for treating this condition.
Molecular identification of fungal species and evaluation of Ochratoxin A contamination in spreading flour in Hamedan bakeries
Authors: Ghafori Shamimeh , Habibipour Reza , Bayat Somayeh
Published: July 2021

Background: The presence of toxicogenic fungi and the production of ochratoxin in flour are dangerous to human health. Therefore, identification of these fungi by molecular and precise methods is essential. The aim of this study was molecular identification of fungal species and investigation of ochratoxin A contamination in flours used in bakeries in Hamadan Methods: In this descriptive-analytical study, 60 flour samples were collected from bakeries in Hamadan. At first, fungi were identified using phenotypic methods such as slide culture. Then, the genus and species of fungi were confirmed by PCR and sequencing of PCR products. ELISA method was used to detect ochratoxin A. Data were analyzed with GraphPad software version 6. Results: Of the 60 samples, 28 flour samples (46.66%) were free of fungal contamination and 32 flour samples (53.33%) were over fungal contamination (104 colonies/gr). Aspergillus and penicillium were the most abundant in samples. The prevalence of fungi in flour of Lavash bread, Sangak Bread, Barbari bread, Taftoon bread (Handmade), Taftoon bread (Machinal made), Stokbrood bread and Loaf bread were 50%, 46%, 35%, 31%, 26%, 18% and 11%, respectively. However, the highest levels of ochratoxin A were reported in flour of Lavash bread (3.98 ppb) and the lowest in Loaf bread (0.66 ppb). There was also a significant relationship between the fungal species and the amount of ochratoxin A production in flour of beards. Conclusion: While phenotypic and genotypic methods did not show the same sensitivity, the presence of ochratoxin in the studied flours indicated the necessity of modification in wheat storage and bakery flours.
Structural equation modeling analysis of the effect of resilience and pain coping strategies on pain perception in patients with spinal pain mediated by psychological symptoms
Authors: Mohammadi Shervin , Malihi Alzakerini Saeed , Pashang Sara , Hoseinian Zakaria Mohamad Mehdi , Golmohamadnajhad Gholamreza
Published: July 2021

Background: Spine pain is one of the most common and costly health problems in developed countries. The purpose of this study was to analyze the structural equation modeling the effect of resilience and pain coping strategies on pain perception in patients with spinal pain: mediated by psychological symptoms. Methods: This study was a correlation study using structural equation modeling. The statistical population of the study was all patients with spinal pain referred to Shams Hospital in Tabriz in 2018, estimated to be 750 patients. The statistical sample of the study was 254 people selected by available sampling based on Krejcie and Morgan’s table. The data gathering tool was the SCL-90 questionnaire, Pain Coping Strategies Questionnaire, Resiliency Scale, and new questionnaire (MPQ). The data were analyzed using structural equation test in Amos software and Bootstrap test. Results: The results of structural equation modeling analysis showed that direct paths from irradiation to pain perception (β=0.000, P<0.01) were significant. There is a direct correlation between coping strategies and pain perception (β=0.31, P<0.01). There is an indirect relationship between vibration, psychological symptoms, and pain perception (β=0.139, P<0.01) There is an indirect relation between coping strategies, psychological symptoms, and pain perception (β = 0/25, P<0.01) Conclusion: It is recommended to develop a comprehensive care plan for patients with spinal pain by enhancing resilience and coping strategies to reduce the level of psychological symptoms in these patients.
Study of microscopic neck metastasis in clinically N0 neck in oral squamous cell carcinoma
Authors: Shahidi Nikzad , Zokaei Nastaran
Published: July 2021

Background: Metastasis of aerodigestive tract cancers to cervical lymph nodes is one of the otolaryngologists’ concerns that relies on a variety of factors such as the size of the primary tumor and its spread. We aimed to study the prevalence of occult cervical metastases in patients with clinical N0 neck in oral cavity squamous cell carcinoma. Methods: In this cross-sectional analytic study, the researchers referred to the archive of Emam Reza Hospital and studied medical files of patients with a definite diagnosis of oral cavity squamous cell carcinoma admitted from April 2011 to April 2016 while collecting relevant data such as age, gender, size of the primary mass, place of the lesion, clinical and pathological nodal involvement. The data was analyzed employing SPSS 19 whereas the statistical significance level in all exams was set at 0.05. Results: Average age of participants was 61.67 ± 14.02, and they were mostly male. Forty-five percent of participants had a clinical N0 neck and the majority of them didn’t have metastasis in the pathological study. The prevalence of metastatic lymph nodes in patients with clinical N0 was 30%. No significant relationship was observed between the number of lymph nodes containing occult metastasis and T of the tumor (P = .578). Conclusion: In squamous cell carcinoma of oral cavity, the prevalence of metastatic lymph nodes in the neck is 30% and is significantly related to the location of the lesion while no significant relationship to T of the tumor is observed.
Transsternal surgery on a patient with a pathological lesion in the thoracic vertebrae and severe destruction of the third thoracic vertebra
Authors: Rajabi Ramin , Ebrahimi Abed , Rahimi Sara , Gholamveisi Behzad
Published: July 2021

Due to the critical and important structures in the thorax, transsternal surgery on thoracic vertebrae is very complex and rarely performed. We report a case of successful transsternal surgery on thoracic vertebrae. In this study, a 27-year-old man presented to the hospital with progressive lower extremity complaints. Pathologic lesions and severe destruction of the T3 vertebra were diagnosed. Considering the location of the lesion, an anterior approach was performed. The results of this operation have been very successful and have some noteworthy points. In this study, transsternal surgery is supported in patients with anterior vertebral conditions.
Fauna urbana: revisão bibliográfica dos mamíferos presentes em fragmentos florestais no estado de São Paulo / Urban fauna: mammals present in forest fragments in the state of São Paulo
Authors: Almeida Ana Beatriz de , Silva Jaqueline Macena Santos , Carvalho Beatriz Regina Rodrigues , Ribeiro Victoria Quagliato Narcizo , Oliveira Edna Maria Cardoso de , Oliveira Murilo Henrique Lara de , Smith Welber Senteio
Published: July 2021

Com a supressão contínua da Mata Atlântica e Cerrado, a fauna, presente nesses biomas, enfrenta desafios em busca de abrigo e recursos. O estado de São Paulo possui importantes fragmentos florestais urbanos que atuam como refúgios para a biodiversidade. O presente estudo teve como objetivo realizar uma revisão bibliográfica dos mamíferos presentes em fragmentos florestais urbanos no estado de São Paulo. Os dados foram considerados de 2000 a 2020 nas bases de dados Google Scholar e Web of Science, a partir de estudos com registros diretos ou indiretos de mamíferos. Dentre as nossas buscas, 11 artigos se enquadraram, onde foram registradas 75 espécies pertencentes a 25 famílias e oito ordens de mamíferos. Foram registradas nove espécies ameaçadas de extinção estadual e duas se categorizam como NT – Near Threatened (Quase ameaçada), já a nível mundial quatro estão em alguma categoria de ameaça e três estão na categoria NT. Dessa forma, os dados levantados ressaltam a necessidade da preservação mesmo de pequenos fragmentos urbanos, que podem atuar como refúgio, passagem ou hábitat da fauna silvestre, podendo inclusive, interligar áreas maiores e formar um corredor ecológico.
Distúrbio respiratório associado a perfuração de laringofaringe por fragmento de casca cana-de-açúcar (Saccharum officinarum) em bovino / Respiratory disorder associated with perforation of the laryngopharynx by a fragment of sugar cane (Saccharum officinarum) in cattle
Authors: De Lima Larissa Serafim , Dos Anjos Giovanna Lemos , E Silva Maurício Machado , Nogueira Mylenna Carvalho , Almeida Ana Maria de Souza
Published: July 2021

A cana-de-açúcar é uma fonte de nutriente amplamente utilizada na nutrição de ruminantes no território brasileiro. Porém, processo inadequados de trituração e moagem da cana-de-açúcar podem dificultar a sua apreensão pelos animais ou até mesmo causar traumas no trato gastrointestinal. O presente estudo relata um caso de um bovino com histórico de dificuldade respiratória e aumento de volume focalmente extenso na região ventral do pescoço que foi a óbito três dias após ser internado em um hospital veterinário do Distrito Federal. Os achados de necropsia revelaram acúmulo de exsudato purulento em tecido subcutâneo e musculatura no pescoço, massa composta com tecido fibrinonecrótica em região músculo cleidocefálico com presença de fragmento de casca de cana-de-açúcar em seu interior. Esse fragmento formava uma fístula entre a massa e a região de laringofaringe permitindo escoamento de exsudato purulento para o rúmen e pulmão. Baseado nos achados macroscópicos, quadro clínico e alterações hematológicas, a causa morte do animal foi insuficiência respiratória decorrente de pneumonia grave, agravada por compressão das vias aéreas superiores pela massa em região de pescoço, associada a processo infeccioso grave.
A redefinição do espaço natural para o lúdico: a interação ecoturismo educação ambiental e preservação do patrimônio natural tendo as reservas particulares do patrimônio natural-RPPNS como elemento mediador / The Redefinition of Natural Space for the Ludic: The Interaction Among Ecotourism. Environmental Education and Preservation of the Natural Asset Taking Account The Particular Reserves of the Natural Heritage-RPPN’s as a Mediating Elemen
Authors: Matteucci Magda Beatriz de Almeida , Vera Rosângela , Figueiredo Reginaldo Santana
Published: July 2021

As Unidades de Conservação - UCs representam territórios apropriados ao turismo sustentável na natureza por se tratar de áreas destinadas à proteção, por vezes, integral dos recursos naturais, admitindo-se, a depender da modalidade de UC, a visitação com objetivos turísticos, recreativos e educacionais. O objetivo deste foi estudar as RPPNs como estratégia para legitimar o ecoturismo como atividade sustentável geradora de renda tendo a educação ambiental como instrumento de preservação ambiental. O estudo foi realizado através da observação participante. A coleta de dados foi realizada por meio de 10 (dez) visitas a UC entre março de 2016 e maio de 2017.  A principal observação foi o número de pessoas que visitavam a UC e quais os procedimentos foram utilizados pelo proprietário visando a proteção dos atributos naturais. Esse estudo sinaliza que, de um modo geral, a estratégia conservacionista do meio ambiente necessita de uma política consistente com o ecoturismo, articulada com a política de Educação Ambiental e a política de conservação da natureza visando harmonizar as ações turísticas com a conservação da natureza, garantindo o bem-estar das populações envolvidas e oferecendo aos turistas um contato íntimo e prazeroso com os recursos naturais e culturais de uma dada região.
Utilizaçao de fototerapia em lesão de membro pélvico de uma espécie de tucano toco (Rhampastos toco) – (Muller-1776), encontrado na Fazenda Palmares-SP / Phototherapy application in a pelvic limb lesion of a toucan toco species (Rhampastos toco) – (Muller- 1776), found at Fazenda Palmares-SP
Authors: Duemes Jessica , Passos Rodrigo Rabello de F. C. e F. , Silva Giulia Costa , Lopes Edris Queiroz
Published: July 2021

O Rhamphasto toco é o maior dos tucanos, podendo ser encontrado em todo o Brasil central e partes da Amazônia. Esta ave é um símbolo marcante da fauna brasileira, por suas características, principalmente pelas cores e pelo formato do bico e tamanho. O presente estudo, que é o primeiro a relatar a eficácia do tratamento coadjuvante com fototerapia em lesão de tibiotarso em Rhamphasto toco, tem como objetivo contribuir no tratamento de lesões em aves, utilizando fototerapia. Sabemos que as aves respondem ao estresse de forma intensa, e a utilização da fototerapia minimiza consideravelmente esses fatores, pois é uma técnica de aplicação rápida, indolor e eficaz. Um exemplar de Rhamphasto toco jovem foi resgato e levado para o IBIMM, apresentando uma lesão em membro pélvico direito e com dificuldade de locomoção, este animal passou por cuidados médicos veterinários onde foi utilizado como tratamento fototerapia associada a aplicação de medicamento tópico. Relacionando o que já foi encontrado sobre o tratamento de feridas em aves, com o resultado deste trabalho, a fototerapia é uma técnica inovadora e extremamente eficaz podendo ser utilizada na rotina clínica de aves para o tratamento de traumas.
Efeito do ácido valpróico e dos fatores de crescimento na plasticidade dos fibroblastos dérmicos felinos / Effect of Valproic acid and growth factors on plasticity of feline dermal fibroblasts
Authors: Berrío Diana Maritza Echeverry , González Constanza Javiera Aguilera , Mansilla Daniela Michel Rojas , Álvarez Lleretny Rodríguez- , Castro Fidel Ovidio
Published: July 2021

As células-tronco mesenquimais (CTM) são utilizadas na terapia celular, isolando-se de diferentes tecidos, incluindo a pele. Os fibroblastos dérmicos têm mostrado características de potência semelhantes às CTMs como expressão de marcadores de superfície e diferenciação para outros tipos de linhagens de origem mesodérmica, principalmente sob a influência de moduladores epigenéticos e fatores de crescimento. A terapia celular em medicina veterinária, especificamente em gatos, representa um desafio devido à invasividade na obtenção de tecidos fonte de CTM, para os quais outras opções menos invasivas estão sendo buscadas para an obtenção dessas células. O objetivo deste estudo foi avaliar o efeito do ácido valpróico - VPA (modulador epigenético) e fatores de crescimento (PRP e h-PDGF-B) na expressão de marcadores de superfície, genes de pluripotência e capacidade de diferenciação mesodérmica de fibroblastos felinos. Fibroblastos de pele foram isolados de gatas e cultivados com VPA e fatores de crescimento por 12 dias. A expressão de Cd90, Cd44, E-Caderina, Snail, Nanog e Oct4 foi avaliada nos dias 5 e 12. O potencial de diferenciação adipogênico, condrogênico e osteogênico dos fibroblastos foi avaliado após 12 dias de tratamento. A expressão de Cd44 aumentou no dia 5 do tratamento com VPA + PRP (p = 0,01). A expressão de Oct4 e Nanog aumentou no dia 5 do tratamento com VPA + h-PDGF-B (p 0,05). Fibroblastos em tratamento com VPA e h-PDGF-B mostraram capacidade de se diferenciar para condrogênese e osteogênese. O protocolo de cultura de células para fibroblastos felinos com VPA e h-PDGF-B confere plasticidade aos fibroblastos felinos ao promover a expressão de Nanog e Oct4, bem como a diferenciação mesodérmica in vitro.
Fixed Point Theorems for the Alternate Interpolative Ciric-Reich-Rus Operator
Authors: Ampadu Clement Boateng
Published: July 2021

In [1], the authors introduced the interpolative Ciric-Reich-Rus operator in Branciari metric space and obtained some fixed point theorems; in this work we present an alternate characterization of the interpolative Ciric-Reich-Rus operator in metric space, and obtain some fixed point theorems.
Research on the Cultural Integration of International Students in Universities: A Perspective of Cross-Cultural Management
Authors: Wang Jiayun
Published: July 2021

With the development of globalization, the number of international students in Chinese colleges will continue to grow, and the education of international students has gradually become an important part of the domestic higher education system. Facing the group of international students in China, its complicated cultural backgrounds and individual differences further increase the difficulty of school management. Therefore, colleges need to start from the perspective of cross-cultural management to strengthen the management of international students, improve and innovate the management system of domestic universities. In this case, schools can reduce the cultural anxiety of international students and improve the cross-cultural awareness of managers, as well as create a better campus environment. In a long run, schools can then create a good environment conducive to the reform, innovation, and development of domestic higher education, and promote the rapid and highquality development of national education.
A Polynomial Composites and Monoid Domains as Algebraic Structures and their Applications
Authors: Matysiak Łukasz , Jankowska Magdalena
Published: July 2021

This paper contains the results collected so far on polynomial composites in terms of many basic algebraic properties. Since it is a polynomial structure, results for monoid domains come in here and there. The second part of the paper contains the results of the relationship between the theory of polynomial composites, the Galois theory and the theory of nilpotents. The third part of this paper shows us some crypto systems. We find generalizations of known ciphers taking into account the infinite alphabet and using simple algebraic methods. We also find two cryptosystems in which the structure of Dedekind rings resides, namely certain elements are equivalent to fractional ideals. Finally, we find the use of polynomial composites and monoid domains in cryptology.
Simulasi Dampak Penghalang pada Gelombang Tsunami Menggunakan Persamaan Air Dangkal dengan Metode Beda Hingga
Authors: Arifin Ahmad Zaenal
Published: July 2021

ABSTRAKTsunami menjadi salah satu bencana alam yang paling berbahaya di daerah sekitar pesisir. Dampak dari gelombang tsunami menyebabkan kerugian yang besar bagi manusia, adanya banyak korban jiwa dan juga besarnya kerugian dalam bidang ekonomi. Artikel ini menunjukkan simulasi dengan pendekatan numerik metode beda hingga untuk menunjukkan dampak keberadan barrier sebagai penghalang gelombang tsunami. Gelombang tsunami dapat direpresntasikan dengan menggunakan persamaan air dangkal. Persamaan air dangkal secara umum digunakan dalam menggambarkan masalah fluida yang didasari oleh konservasi fisik dan juga dapat digunakan untuk menggambarkan terjadinya gelombang tsunami. Persamaan air dangkal berbentuk persamaan diferensial parsial sehingga dapat diselesaikan menggunakan metode beda hingga. Hasil simulasi persamaan air dangkal menunjukan bahwa persamaan air dangkal dapat merepresentasikan gelombang tsunami dengan konstruksi penghalang dan diketahui bahwa pembangunan sebuah penghalang dapat memecah gelombang tsunami dan dapat mengurangi kekuatan gelombang. ABSTRACTOne of the most dangerous natural disasters in the coastal area is Tsunami. The tsunami waves impact caused considerable losses to humans, many casualties, and significant losses in the economic field. This article shows a simulation using the numerical approach of finite difference methods to deliver the barrier's impact is a tsunami wave barrier. Tsunami waves can be represented using the shallow water equation. The shallow water equation is generally used to describe fluid problems based on physical conservation and define tsunami waves. The shallow water equation is in the form of a partial differential equation to be solved using the finite difference method. The shallow water equation's simulation results show that the shallow water equation can represent a tsunami wave with a barrier construction. It is known that the construction of a barrier can break the tsunami waves and reduce the strength of the waves.
Ruang Fase Tereduksi Grup Lie Aff (1)
Authors: Kurniadi Edi
Published: July 2021

ABSTRAKDalam artikel ini dipelajari ruang fase tereduksi dari suatu grup Lie khususnya untuk grup Lie affine  berdimensi 2. Tujuannya adalah untuk mengidentifikasi ruang fase tereduksi dari  melalui orbit coadjoint buka di titik tertentu pada ruang dual  dari aljabar Lie . Aksi dari grup Lie    pada ruang dual  menggunakan representasi coadjoint. Hasil yang diperoleh adalah ruang Fase tereduksi  tiada lain adalah orbit coadjoint-nya yang buka di ruang dual . Selanjutnya, ditunjukkan pula bahwa grup Lie affine     tepat mempunyai dua buah orbit coadjoint buka.  Hasil yang diperoleh dalam penelitian ini dapat diperluas untuk kasus grup Lie affine  berdimensi  dan untuk kasus grup Lie lainnya.ABSTRACTIn this paper, we study a reduced phase space for a Lie group, particularly for the 2-dimensional affine Lie group which is denoted by Aff (1). The work aims to identify the reduced phase space for Aff (1) by open coadjoint orbits at certain points in the dual space aff(1)* of the Lie algebra aff(1). The group action of Aff(1) on the dual space aff(1)* is considered using coadjoint representation. We obtained that the reduced phase space for the affine Lie group Aff(1) is nothing but its open coadjoint orbits. Furthermore, we show that the affine Lie group Aff (1) exactly has two open coadjoint orbits in aff(1)*. Our result can be generalized for the n(n+1) dimensional affine Lie group Aff(n) and for another Lie group.
SOSIALISASI TENTANG PENERAPAN PROTOKOL KESEHATAN PENCEGAHAN COVID-19 DI KABUPATEN BATU BARA PROVINSI SUMATERA UTARA
Authors: Kasim Felix , Bangun Sri Melda , Paranduri Anggi Isnani , Sihite Henri Gudmen , Saputri Ika Nur , Sitepu Kuat
Published: July 2021

The COVID-19 pandemic has become a world health problem since the end of 2019, this case is increasing and spreading rapidly throughout the world, including Indonesia. Batu Bara Regency is one of the districts experiencing an increase in confirmed cases of COVID-19. The purpose of this paper is to provide socialization about the implementation of the COVID-19 prevention health protocol in Batu Bara Regency, North Sumatra Province. The method of implementing the activity is in the form of observation and socialization about the implementation of the COVID-19 prevention health protocol in the community. Based on the results of the activities that have been carried out, the community has a better understanding of health protocols in prevention efforts, it is hoped that it will have an impact on changing people's behavior to better comply with and implement the COVID-19 prevention health protocol so that there will be a significant decrease in cases.
SOSIALISASI PEMBERDAYAAN KADER POSYANDU DI PUSKESMAS TANJUNG MORAWA
Authors: Simarmata Marice , Saputri Ika Nur , Octavariny Raisha , Panjaitan Delita Br , Irmayani Irmayani , Nurianti Irma
Published: July 2021

Stunting in infants and toddlers is a chronic nutritional problem that requires comprehensive management and involves various cross-sectors. In 2018, it was determined that stunting management was a national development priority through the National Action Plan for Nutrition and Food Security in Indonesia. Tanjang Morawa District is one of the cases where there are cases of stunting. Stunting management efforts by optimizing conditions in the first 1000 days of life (HPK) can be implemented at Posyandu. Posyandu as a form of community empowerment in the health sector has a strategic role, however, because posyandu cadres have a diverse educational and socio-cultural background, their knowledge and skills need to be continuously updated. In the case of stunting, various studies have shown that the knowledge and skills of cadres related to stunting and prevention efforts are mostly not good, therefore efforts to increase the capacity of posyandu cadres are important. The training activities for 20 posyandu cadres were carried out in three stages, namely program socialization, training preparation and implementation, using a deductive model approach, training materials were compiled based on field observation data which was then discussed with expert sources. After training posyandu cadres can better understand balanced nutrition, early detection of stunting and the important role of posyandu cadres to inform optimal nutrition at 1000 HPK as an effort to prevent stunting and identify risk factors for stunting in the posyandu working area. It is known from the increase in the results of knowledge on the test after training. It is hoped that this capacity building will be made as continuous training that is periodic and well programmed
PEMBERDAYAAN DUKUNGAN KELUARGA TERHADAP PENINGKATAN KEPATUHAN PENERAPAN PROTOKOL KESEHATAN PENCEGAHAN COVID-19
Authors: Satria Beni , Kasim Felix , Paranduri Anggi Isnani , Irmayani Irmayani , Bangun Sri Melda Br , Sitepu Kuat
Published: July 2021

COVID-19 became a world health problem in early 2020. This case began with information from the WHO on December 31, 2019 which stated that there was a cluster case of pneumonia with unclear etiology in Wuhan City, Hubei Province, China. This case continued to grow until there were reports of deaths and imports outside China. In Indonesia, on March 2, 2020, Indonesia has reported 2 (two) confirmed cases of COVID-19. Cases are increasing and spreading rapidly throughout Indonesia. This paper aims to empower family support to improve compliance with the implementation of COVID-19 prevention health protocols. The method of implementing the activity is in the form of observation and providing health education about the application of health protocols in an effort to prevent COVID-19 to the community, based on the results of activities carried out by the community enthusiastically welcoming this activity. Through this activity, it is hoped that there will be an increase in compliance in the application of the COVID-19 prevention health protocol so as to suppress the decline in COVID-19 cases.
SOSIALIASI SKRINING FITOKIMIA EKSTRAK ETANOL UMBI BAWANG MERAH (Allium cepa L.)
Authors: Hasibuan Ahmad Syukur , Edrianto Vicky
Published: July 2021

Bawang merah (Allium cepa L) banyak mengandung senyawa aktif yang memiliki efek farmakologi. Etanol adalah pelarut yang mempunyai universal serta memiliki sifat netral, absorbsi baik, tidak beracun dan stabil sehingga dapat digunakan untuk ekstraksi umbi bawang merah. Skrining fitokimia dilakukan untuk mengetahui golongan senyawa yang terkandung dalam ekstrak umbi bawang merah. Penelitian ini dilakukan ekstraksi menggunakan metode maserasi selama 5 hari dan dilanjutkan dengan remaserasi selama 2 hari. Kemudian ekstrak yang didapat dilakukan skrining fitokimia. Hasil skrining fitokimia umbi bawang merah menggunakan pelarut etanol menunjukkan adanya kandungan senyawa flavonoid, tanin, saponin, alkaloid dan steroid/terpenoid. Sosialiasasi hasil skrining ekstrak etanol umbi bawang merah tersebut dilakukan terhadap mahasiswa pada saat pengajaran di kelas menggunakan aplikasi zoom.