bluuebunny/crossref_metadata_2025 huggingface dataset:
Coupled experimental and theoretical study of hydroxyapatite ceramics
Authors: Kribaa Oum Keltoum , Labidi Chams Edoha , Djouama Hanane , Laacher Lamia
Published: July 2023

Hydroxyapatite is a biomaterial that has great importance in the medical field and is commonly used as an implant to replace amputated bone in tissue and organ transplants and in drug delivery systems. Quantum chemistry is based on the density functional theory (DFT), which is an important tool for understanding structural arrangements and explaining the physicochemical properties of complexes. This work is mainly based on the synthesis of hydroxyapatite using the double-decomposition method. Fine hydroxyapatite powder was characterized by different techniques such as infrared spectroscopy, the X-ray diffraction method, scanning electron microscopy and density measurement. The crystalline microstructure of hydroxyapatite is hexagonal with lattice parameters a = b = 9.4260 Å and c = 6.8850 Å and space group P63/m. Hydroxyapatite has a porous surface particle morphology with a regular spherical shape. An agreement between the energies and the vibrational frequency of connection which are characteristic of the infrared spectrum. The geometry of the complex isolated using the DFT method was optimized in open air and in various solvents. Different functionals were chosen to determine the energies of excitation and the forces of the associated oscillator of the studied complex. Theoretical absorption spectra were obtained using the GaussView and Origin software programs.
Editorial: Conceptualising Education in Wales Through Reform, Identity, Language and History
Authors: Crick Tom , Thomas Enlli , Beauchamp Gary
Published: July 2023

Editorial (Wales Journal of Education 25.1)
How do we achieve the third space? The challenges and strengths of partnership working to deliver a flexible PGCE Programme in Wales
Authors: Glover Alison , Stewart Sarah , Thomas Angela , Thomas Rachel
Published: July 2023

Wales has devolved powers for education and training and there has been much focus on the quality of education and related factors in Wales in recent years. The education system in Wales is shifting from a 'managerial' one to being based more on trust and professionalism and it is increasingly recognised that the efforts being made to ensure this educational reform is coherent and effectively communicated are successfully progressing. Reforms to Initial Teacher Education (ITE) in Wales provide examples of this successful progress; as the leadership and management of ITE programmes are now led by partnerships of a university working in collaboration with lead partner schools. The new two-year flexible distance learning approach of The Open University in Wales PGCE Programme demonstrates such success, as students study on a part-time or salaried PGCE. Third space theory considers how truly effective and fair collaborative partnership working is achieved without the existence of hierarchical relationships. Twenty stakeholders gave their views on the challenges and strengths of the new Open University Partnership during the development and early implementation stage. The early challenges focus on processes, such as communication issues and the quantity of programme documents, with it recognised that the global pandemic is a contributory factor for the concerns raised. The strengths of a clear shared vision, co-construction of programme materials and collaborative governance indicate the progress the new PGCE programme is making towards existing in the 'third space'.
Exploring the Discursive Construction of National Identity Through the Building of the New Curriculum for Wales
Authors: Roberts Alys Lowri
Published: July 2023

Wales is currently undergoing its largest ever educational reform in way of a new curriculum, within this reform multiple themes of identity and nationality are raised and used. This article uses Foucauldian discourse analysis to explore the discursive construction of identity in the building of the new curriculum. Through locating and exploring the subjectification of learners’ identity, this paper discusses the potential for learners’ subject position for identities and belonging within the new curriculum. It locates identity as diverse, fluid, spatial and strategic and explores the potential outcomes for these discursive constructions in regards to the subject positions of learners. It found these discourses to be interacting and in relation with one another, but also with the potential for conflict and contradiction. It notes many complexities and nuances in themes of identities and belonging within the curriculum. The work found potential for belonging as well as barriers such, as alienation and exclusion for learners. Finally, it offers some caution for ensuring these barriers can be overcome for all learners in the implementation of the new curriculum.
Tuag at y continwwm iaith: Diffiniadau a goblygiadau ar gyfer cyflwyno'r Gymraeg yn y cwricwlwm newydd i Gymru
Authors: Lovell Alexander Edwin
Published: July 2023

Gyda chyflwyno Cwricwlwm i Gymru 2022 yn prysur agosáu, mae’n amserol trafod un o’r prif ddatblygiadau mewn perthynas â’r Gymraeg yn y cwricwlwm newydd, sef y continwwm iaith. Er mai term sydd wedi’i ddefnyddio’n aml gan academyddion a llunwyr polisi fel ei gilydd yw “continwwm”, mae i’r term sawl dehongliad, nid yn unig yn y llenyddiaeth ar ddwyieithrwydd ac addysg ddwyieithog, ond hefyd ym mholisi iaith ac addysg Cymru. Diben y papur hwn yw adolygu’r prif ddehongliadau o’r continwwm iaith, cyn cynnig dehongliad amgen, yr hyn y mae’r ymchwilydd yn ei alw’r “continwwm amlgymwyseddau”, sy’n anelu at bontio rhwng y damcaniaethol a’r ymarferol gan gysylltu’r cysyniad o gontinwwm iaith â’r cysyniad o gontinwwm dysgu, fel y’i cydnabyddir yn y cwricwlwm newydd. Trafodir goblygiadau cyflwyno’r continwwm ar gyfer y Gymraeg mewn ysgolion cyfrwng Saesneg yn benodol.
Evaluación de la información documentada (norma ISO 9001: 2015).
Authors: Moya Acosta Manuel Jesús , Barreto Michel E. , Goncalves Irene , Morales Ángela
Published: July 2023

Para asegurar la calidad de los trabajos con animales de laboratorio, es fundamental estandarizar sus procesos de cría y mantenimiento. La norma ISO 9001:2015 reúne los requisitos que certifican los Sistemas de Gestión de Calidad de una organización. El trabajo se enfoca primordialmente en el establecimiento y evaluación de información documentada de los procesos a los que se hace referencia en el requisito 7.5 de la ISO 9001:2015. Este requisito normativo hace parte de un sistema de gestión que se enfoca en la satisfacción del cliente con respecto a cumplimiento de sus necesidades. La presente investigación. Se realizó una investigación descriptiva y exploratoria. Se diseñó un instrumento (encuesta) donde se recabó información sobre el uso de la documentación en los procesos productivos y experimentales. Se estudiaron 22 bioterios convencionales, registrados en la Asociación Venezolana para la Ciencia de Animales de Laboratorio (avecal). El instrumento se envió vía correo electrónico a los Jefes de Bioterio. Se recogieron y tabularon los datos en función de las variables investigadas. Se evidenció que el 81,8% de estos bioterios no cuenta con documentos que permitan realizar control y seguimiento de sus procesos. Igualmente, los responsables desconocen del marco jurídico nacional, como la Ley Orgánica del Sistema Venezolano para la Calidad, las Normas Generales de Control Interno de la Contraloría General de República y la Norma ISO 9001:2015. Se recomienda el diseño de una guía metodológica, para que los bioterios nacionales elaboren sus documentos siguiendo la cláusula 7.5 de la norma ISO 9001:2015 con el fin de mejorar la eficiencia de sus procesos.
Analysis of orthopaedic injuries in CT pan scans of polytrauma patients at a quaternary academic hospital
Authors: Laney W , Naicker D , Milne B , Omar S
Published: July 2023

BACKGROUND: In South Africa, doctors commonly treat patients suffering major trauma, often with multiple injuries, which necessitates the demand for a rapid diagnostic assessment. Whole body computed tomography (CT pan scan) allows for a rapid multisystem injury diagnosis. There is a scarcity of literature evaluating the extent of orthopaedic injuries in CT pan scan of polytrauma patients. The aim of the study was to evaluate the local epidemiology of orthopaedic injuries in polytrauma patients who underwent a CT pan scan. METHODS: A retrospective, observational analysis, based at an academic hospital, was done of polytrauma patients who underwent a CT pan scan during a two-year period. A database was compiled by accessing the picture archiving and communication system. RESULTS: A total of 296 polytrauma patients had a reported CT pan scan; 85% were male and 15% were female with a median age of 33 years. The most common mechanism of injury was motor vehicle accidents (33.1%). A total of 1 012 injuries were identified; 196 were spinal fractures (mostly cervical), 137 were pelvic/sacral fractures, and 101 were long bone fractures of the upper and lower limbs. The most frequent non-orthopaedic injury sustained was a chest injury. In a pedestrian-vehicle accident, the most common combination of injuries was a chest injury with an associated pelvic/sacral injury. Interpersonal and intentional injuries were significantly associated with a higher risk of thoracic spine fractures (relative risk [RR] 1.8, CI 1.1-2.9), whereas road traffic accidents were significantly associated with a higher risk of scapula/clavicula fractures (RR 2.0, CI 1.2-3.5) and a higher risk of tibia/fibula fractures (RR 3.5, CI 1.2-10.3). CONCLUSION: The majority of polytrauma patients were young males involved in road traffic accidents. A patient involved in a road traffic accident is 3.5 times more likely to sustain a tibia/fibula fracture as opposed to any other fracture. One in four patients who sustained a chest injury had an associated cervical spine injury, and one in three patients had a pelvic/sacral injury, and similarly with head injuries. The findings of this study highlight injury patterns that should be anticipated in polytrauma patients. Level of evidence: Level 3
Decolonial Post-Tribal Interpretation: Proto-Tribal Socio-Economic Contestation in 3 Reigns 12:24p-t
Authors: West Gerald O.
Published: July 2023

This article reflects on the socio-economic and tribal dimensions of both 3 Reigns 12:24p-t and the post-1994 South African transition. Mahmood Mamdani's recent book, Neither Settler nor Native, provides an analysis of political decolonisation in post-apartheid South Africa, in which he identifies two areas of failure within the significant gains made during South Africa' s transition from apartheid to democracy-socio-economic justice and tribalisation. These two areas are the unfinished business of our substantive decolonisation of the political. In this article, I use Mamdani' s analysis as an exegetical dialogue partner, probing the socioeconomic and tribal dimensions of 3 Reigns 12:24p-t and identifying this text as a proto-tribal text which documents the emergence of tribal economics. Methodologically, this article establishes a to-and-fro tripolar movement between the contemporary South African context and the biblical text.
Exploring Retributive Justice in Job 9:1-24 in the Context of Christianity in Enugu State, Nigeria
Authors: Odo Damian O. , Uwaegbute Kingsle I. , Chukwuma Onyekachi G.
Published: July 2023

This article investigates the idea of retributive justice in Job 9:1-24 in the context of Christianity in Enugu State. In this pericope, Job refuted the inflexible doctrine of his sage friends who interpreted his misfortune from the standpoint of moral transgression, as they accused him of being culpable for the calamity that enveloped him. Job argued that there is no direct nexus between sin and suffering since the righteous and the wicked are indiscriminately rewarded. The study employed literary analysis as its methodology. Like Job of the Old Testament, some Christians in Enugu State experience diverse misfortunes, but their suffering is not necessarily because of their sins. This situation strongly contrasts with the erroneous view of the exponents of retributive justice that every misfortune is the consequence of sin. The study demonstrates that the suffering of Christians in Enugu State is an existential reality that cannot be explicated through the lens of retributive justice.
An empirical analysis of the impact of mobile instant messaging for collaborative learning during the Covid-19 lockdown in a rural-based university
Authors: Mashau Nkhangweni Lawrence
Published: July 2023

The world-wide outbreak of Covid-19 effected radical change in most institutions of higher learning. These institutions were forced to adopt any technologies at their disposal to continue with teaching and learning and, during that time, many students and lecturers at rural-based universities adopted mobile instant messaging (MIM) for collaborative learning. This study investigates the impact of MIM for collaborative learning during a Covid-19 lockdown in one rural-based university. Data were collected from both students and lecturers using a closed-ended questionnaire, and analysed using IBM SPSS Statistics. The study found that MIM had a positive impact on collaborative learning in the rural-based university during the Covid-19 lockdown.
Hermenéutica y tecnología como un diálogo salvífico para la pedagogía actual
Authors: Tillería-Aqueveque Leopoldo
Published: July 2023

El escrito plantea la controversial tesis de que el diálogo entre hermenéutica y tecnología resulta decisivo para salvaguardar una pedagogía originaria y al servicio de un ciudadano libre y responsable. Para ello, se vale de la hermenéutica de la facticidad de Heidegger, como una estructura interpretativa que reordena el sentido de las nociones de técnica y tecnología hasta ahora oculto en la tradición. Se sugiere que la relación originaria entrehermenéutica y tecnología se revelaría como una relación salvífica para una pedagogía centrada no el modo de instruir al ciudadano respecto de lo que debe o no debe saber, sino en la forma primitiva y más auténtica de comprenderse a sí mismo. Una consideración más propia de la conexión entre tecnología y pedagogía, si ha de fundarse efectivamente en una hermenéutica filosófica como la heideggeriana, debiese poder ejecutar lo que pudiera llamarse “giro hermenéutico”; es decir, sería la relación fenomenológica del ser humano con la tecnología lo que determinaría el alcance, la direccionalidad y la pertinencia de cualquier enfoque educativo. Inopinadamente, se interroga si pudo ser Platón quien arrojó luz a la tarea desocultante de Heidegger de invertir los polos entre tecnología y mundo, y, por lo mismo, determinó una hermenéutica de la facticidad en la que el desocultamiento poético allanase el camino hacia una pedagogía salvífica del pensar originario.
Uso de las paradojas como recursos didácticos que desarrollan el pensamiento crítico en los estudiantes
Authors: Mora-Ramírez Rafael Félix
Published: July 2023

Últimamente, la educación se ha visto desafiada por el contexto digital que beneficia a las plataformas virtualesque contienen creaciones de youtubers o influencers, los cuales se enfocan en entretener más que en formar integralmente al estudiante. En este sentido, este artículo considera a las paradojas como recursos didácticos que pueden ayudar al desarrollo del pensamiento crítico del estudiante durante su formación. Esta investigación es documental y se basa en la consulta de fuentes escritas y de internet. Comienza aclarando los conceptos de falacia y reducción al absurdo, pues las paradojas han sido vistas como falacias muy sutiles por algunos estudiosos como Bertrand Russell y, además, hay quienes utilizan las paradojas para realizar deducciones, como ocurre en la reducción al absurdo que se aplica en el argumento ontológico de San Anselmo de Canterbury. Enseguida, se analiza una lista de paradojas, pero con el objetivo de que puedan ser utilizadas en un aula de clase. Así, se trata sobre algunas paradojas como la paradoja de Aquiles y la Tortuga, la de Galileo, la del hotel de Hilbert, la de Tristam Shandy, la de Protágoras, etc. Este trabajo se cierra tratando de explicitar el aspecto afectivo y emocional que un estudiante experimenta cuando trata con esta clase de problemas.
Percepción estudiantil sobre la discriminación y el racismo en la educación superior
Authors: Bravo-Mancero Patricia Cecilia , Guffante-Naranjo Tania María , Falconí-Uriarte Martha Yolanda
Published: July 2023

Este artículo examina la percepción estudiantil sobre discriminación y racismo en la educación superior. La pregunta que orienta el estudio es: ¿Qué percepciones tienen los estudiantes sobre la discriminación y el racismo en el contexto universitario? El racismo es considerado una ideologíaque naturaliza la desigualdad y que toma como base las particularidades biológicas para establecer situaciones de diferenciación social. Así, la discriminación se refiere a circunstancias de exclusión,segregación, restricción debido a estereotipos que limitan los derechos de las personas. El estudio fue de carácter cuantitativo, descriptivo y transversal. Participaron 263 estudiantes provenientes decuatro facultades de la Universidad Nacional de Chimborazo. Los datos de la investigación fueron recogidos mediante el Cuestionario de Percepción sobre racismo y discriminación en la EducaciónSuperior. Se evidencia que el 29,9 % de estudiantes manifiesta haber experimentado racismo y discriminación; el 89,7 % afirma que nunca lo han ejercido y el 57,7 % aduce que ha observado diversas manifestaciones en las interacciones. Los principales focos de la discriminación son: etnia, género, identidad sexual, situación socioeconómica y/o discapacidad. Las manifestaciones de la exclusión son explícitas e implícitas y las formas más evidentes de ejercerlos son a través deviolencia psicológica, verbal y física. Finalmente, existe una negación y naturalización del fenómenoque se encuentra enraizado en la dinámica institucional.
Toda linha tem um ponto de partida: relato de um psicólogo residente sobre a construção da Linha de Cuidado em Saúde Mental Infantojuvenil de Dias d’Ávila/BA
Authors: Gomes Junior Wellington Ramos , Teixeira Dhara Santana
Published: July 2023

INTRODUÇÃO: As Linhas de Cuidado têm-se mostrado como importantes ferramentas para a gestão do cuidado, facilitando o fluxo assistencial, integrando serviços, instituições e atores responsáveis pelo cuidado àquela população específica; no campo da saúde mental infantojuvenil, essas ferramentas mostram-se como objetos importantes na luta pelo cuidado integral, humanizado e em liberdade. OBJETIVO: Descrever o processo inicial de planejamento, discussão e elaboração da Linha de Cuidado em Saúde Mental Infantojuvenil do município de Dias d’Ávila-BA. METODOLOGIA: A experiência relatada ocorreu durante estágio na Rede de Atenção Psicossocial (RAPS) do município, quando o autor era residente no Programa de Residência em Saúde da Família (FESF-SUS/FIOCRUZ). Para tal, foram utilizadas anotações e registros pessoais do autor, além de fichas e livros de registro do Centro de Atenção Psicossocial (CAPS). Trata-se de um estudo descritivo, de abordagem qualitativa, no formato de relato de experiência. RESULTADOS: Durante as discussões, além do debate de temas centrais, como racismo e sexismo, foram levantadas possibilidades assistenciais e critérios de encaminhamento, tendo como referência o CAPS. CONCLUSÃO: Os objetivos da pesquisa foram cumpridos e, além disso, relatar essa experiência proporcionou ao campo, de modo geral, um olhar mais cuidadoso em relação ao tema proposto.
Reverse transcription, primer pools preparation and multiplex PCR steps for DENV2 serotype v1
Authors: Ceschini Laís
Published: July 2023

This step-by-step protocol describes the cDNA synthesis, primer pools preparation and multiplex PCR conditions with the main goal to sequence the complete genome of DENV2 serotype strains.
Testimony on a successful lab protocol to disrupt Chlorella vulgaris microalga cell wall v2
Authors: Coelho Diogo
Published: July 2023

Over the last decades, microalgae have gained popularity due to demand for novel environmental green solutions and development of innovative mass-production sources for multiple processes, including animal feed and human diet, turningmicroalgae into an exquisite candidate for several ecofriendly technologies. Notwithstanding, there is a catch. Most species of microalgae, as the case of common Chlorella vulgaris (C. vulgaris)display a recalcitrant cell wall, characterized by a complex matrix of polysaccharides and glycoproteins, which constitutes a major barrier for monogastric species digestibility and extraction of inner valuable nutritional compounds. To overcome this limitation, the development of feed enzymes, in particular Carbohydrate-Active enZymes (CAZymes) with capacity to disrupt C. vulgariscell wallmay contribute to improve the bioavailability of these microalgae compounds in monogastric diets, namely at high levels of incorporation. In order to disclosure novel combination of feed enzymes to disrupt C. vulgaris cell wall, a lab protocol was implemented by our research team containingthe following key steps: after microalgae cultivation and having available a repertoire of two hundred pre-selected CAZymes produced by high-throughput technology, thestep 1 is the individual screening of the most functional enzymes on disrupting C. vulgariscell wall (versus a control, defined as the microalgae suspension incubated with PBS) and the determination of reducing sugars released by the 3,5-dinitrosalicylic acid (DNSA) method; step 2 concerns on finding the best CAZymes cocktail, testing the synergistic effect of enzymes, to disrupt C. vulgariscell wall (in parallel with running the control) along with characterization of each enzyme thermostability and resistance to proteolytic attack, to which feed enzymes are subjected in the animal gastrointestinal tract; step 3 is the assessment of C. vulgaris cell wall degradation degree by measuring the amount of reducing sugars released by the DNSA method, fatty acid analysis by gas chromatography (GC) with flame ionization detector(FID), oligosaccharides quantification byhigh performance liquid chromatography(HPLC) equipped with an electrochemical detector (ECD),protein content by the Kjeldahl method, and various pigments (chlorophylls a and b, and total carotenoids) in the supernatant. In the correspondent residue, we also assessed cellular counting using a Neubauer chamber by direct observation on a bright-field microscope and fluorescence intensity, after staining with Calcofluor White for both control and CAZymes cocktail treatments, on a fluorescence microscope. Beyond animal feed industry with impact on human nutrition, our lab protocol may increase the yield in obtaining valued constituents from C. vulgarismicroalga for other biotechnological industries. (Thelast stepin this version contains a supplemental video with extra context and tips, as part of the protocols.io Spotlight series, featuring conversations with protocol authors.)
bacia hidrográfica e sua topografia:
Authors: Reis do Nascimento Lopes Elfany , Coutinho de Oliveira Caroline
Published: July 2023

O estudo analisou a fragmentação florestal em função dos atributos topográficos existentes na bacia hidrográfica do Rio dos Mangues entre 1990 a 2018. Segmentou-se a área de vegetação dos mapeamentos temporais de uso do solo da cidade de Porto Seguro, classificando-os em tamanhos pequenos, médios e grandes. Extraiu-se para cada fragmento a média das cotas altimétricas e declividade, obtidos por modelo digital de elevação. Analisou-se a adequação do Plano Diretor Urbano e do Plano Municipal de Conservação e Recuperação da Mata Atlântica como instrumentos para a conservação da bacia hidrográfica. Identificou-se o aumento da fragmentação florestal na bacia hidrográfica, seguindo os padrões de fragmentação em áreas atlânticas, com fragmentos menores em áreas mais baixas e planas. Os instrumentos de gestão são potenciais para a gestão da bacia hidrográfica, mas possuem metas ainda não realizadas.
Mobility Hubs: A Way Out of Car Dependency Through a New Multifunctional Housing Development?
Authors: Krüger Arvid , Altrock Uwe
Published: July 2023

Today’s urban design of new quarters in the fringes of German metropolises shows a renaissance of the garage building as a cluster for car parking. In contrast to the past, parking garages are planned as multifunctional “mobility hubs.” Planners enrich them with new mobility and sharing options and incorporate sports or social infrastructure facilities on the roof and the ground floor, thus contributing to vibrant neighborhoods. In contrast to the internationally renowned example of Nordhavn (Copenhagen), we observe a decentralization in the mainstreaming of the approach: Mobility hubs are to become constitutive parts of small subcenters. In this respect, they can be seen as a common leitmotiv for urban design in Germany’s metropolises. The hubs form a new model of local mobility, guaranteeing a certain flow of pedestrians and freeing the adjacent streets of car traffic. Integrated into a system of alternative modes of transportation and nearby mass transit, those infrastructural and mobility clusters might contribute to a change in mobility habits and ultimately reduce car dependence. If their underlying mobility policies can be implemented and if they are ultimately more successful than traditional parking garages or even create an incentive not to use private cars at all remains open to further investigation. For this purpose, the article will trace the emergence of mobility hubs in the discourse and practice of urban design with a particular focus on major new developments at the periphery of German cities. It analyzes urban design competitions and the formal planning and implementation following them.
Promoting Wellness for an Inclusive Perinatal Population: Strategies for Counselors
Authors: Devooght Andrea , Stinnett Rachel , Philippi Kelsey J. , Cahill Ada , Neuer Colburn Anita A.
Published: July 2023

The authors present wellness-supporting strategies for counselors working with anyone looking to add a child to their family. Current literature is largely heteronormative and cisnormative, with a predominant focus on mothers’ experiences, and still often limited in its consideration of multicultural factors and impacts across levels of intersectional wellness. Focusing on populations typically ignored in the literature, the authors present risk and protective factors associated with perinatal mood and anxiety disorders and apply the socio-ecological model of mental health and well-being to demonstrate how counselors can use their own and their clients’ levels of influence to promote wellness.
Sinkhole Detection in IOT using Elliptic Curve Digital Signature
Authors: Hepsiba C. Linda , Priyadarsini R. Jemima
Published: July 2023

A variety of smart applications, including homes, transportation, health, and robots in industries, are starting to gain interest due to the fast expansion of Internet of Things (IoT). Smart devices are made up of sensors and actuators that actively involved in monitoring, prediction, security, and information sharing in the IoT ecosystem. These state-of-the-art (SOTA) technologies enable people to monitor and manage their unified milieu in real-time. IoT devices are nevertheless regularly used in hostile situations, where attackers try to grab and penetrate them to take over the entire network. Due to the possibility of selective forwarding, sinkhole, blackhole, and wormhole attacks on IoT networks is a serious security risk. This research offers an effective method using a digital signature to detect and mitigate sinkhole attacks on IoT networks to resolve this problem. By doing a thorough security study of this suggested system, it shows how safe it is and how resistant it is to secure sinkhole attack detection. In this study, elliptic curve digital signature algorithm is used along with the node ranker to detect the sinkhole attack in IoT environment. According to the performance analysis and experimental findings compared to other research, the suggested system offers good detection accuracy and greatly lowers the overhead associated with computing, communication, and storage.
Enhanced Grey Wolf Optimization based Hyper-parameter optimized Convolution Neural Network for Kidney Image Classification
Authors: Priyanka Priyanka , Kumar Narender , Kumar Dharmender
Published: July 2023

Over the last few years, Convolution Neural Networks (CNN) have shown dominant performance over real world applications due to their ability to find good solutions and deal with image data. However their performance is highly dependent on the network architecture and methods for optimizing their hyper parameters especially number and size of filters. Designing a good CNN architecture requires human expertise and domain knowledge. So, it is difficult in CNN to find sufficient number and size of filters for classification problems. The standard GWO algorithm used for any optimization purpose suffers from some issues such as slow convergence speed, trapping in local minima and unable to maintain balance between exploration and exploitation. In order to have proper balance between these phases, two modifications in GWO are introduced in this paper. A technique for finding optimum CNN architecture using methods based on Enhanced Grey Wolf Optimization (E-GWO) is proposed. The paper presents optimization of hyper parameters (numbers and size of filters in convolution layer) of CNN using E-GWO to improve the performance of the model. Kidney ultrasound images dataset collected from ultrasound centre is used to evaluate the performance of the proposed algorithm. Experimental results showed that optimization of CNN with E-GWO outperformed CNN optimized with traditional GA, PSO and GWO and conventional CNN yielding 97.01% accuracy. At last, the obtained results are statistically validated using t-test.
Augmented MRI Images for Classification of Normal and Tumors Brain through Transfer Learning Techniques
Authors: Angurala Mohit
Published: July 2023

A brain tumor is a severe malignant condition caused by uncontrolled and abnormal cell division. Recent advances in deep learning have aided the health business in Medical Imaging for the diagnosis of numerous disorders. The most frequent and widely used deep learning algorithm for visual learning and image recognition. This research seeks to multi-classification tumors in the brain from images attained by Magnetic Resonance Imaging (MRI) using deep learning models that have been pre-trained for transfer learning. As per the publicly available MRI brain tumor dataset, brain tumors identified as glioma, meningioma, and pituitary, are accounting for most brain tumors. To ensure the robustness of the suggested method, data acquisition, and preprocessing are performed in the first step followed by data augmentation. Finally, Transfer Learning algorithms including DenseNet, ResNetV2, and InceptionResNetv2 have been applied to find out the optimum algorithm based on various parameters including accuracy, precision, and recall, and are under the curve (AUC). The experimental outcomes show that the model’s validation accuracy is high for DenseNet (about 97%), while ResNetv2 and InceptionResNetv2 achieved 77% and 80% only.
Remembering Alexander Ivanovich Panyushkin: the first neurosurgeon at the Lenringad Road Hospital, successor of the neurosurgical school of the Military Medical Academy named after S.M. Kirov
Authors: Vavilova Anastasia A. , Khilova Yuliana K.
Published: July 2023

This article focuses on the life and professional achievements of Alexander Ivanovich Panyushkin (19332022), who served as the first neurosurgeon at the Oktyabrskaya Railway Road Hospital and later became its chief physician from 1974 to 1999. Panyushkin obtained his neurosurgical specialization at the Department of Neurosurgery of the Military Medical Academy named after S.M. Kirov, studying under renowned academic neurosurgeons such as V.A. Shustin, V.A. Grebenyuk, and B.A. Samotokin. In the 1960s, Panyushkin studied under renowned academic neurosurgeons such as Associate Professor V.A. Shustin (a specialist in treating discogenic radiculitis), Professor V.A. Grebenyuk, and Professor B.A. Samotokin (head of the department) and other figures and doctors of the academy. The article highlights the establishment of the neurosurgical department of the Road Hospital, which served as the base of the Department of Neuro surgery of the Military Medical Academy named after S.M. Kirov, as well as the close relationship between the hospital and the academy for many years. It also explores Panyushkins significant contributions to the diagnosis and surgical treatment of discogenic lumbosacral radiculomyeloishemia, as reflected in his well-known monographs. The article provides insights into Panyushkins remarkable career journey from a young surgeon to the head physician of a renowned spinal neurosurgical department in Leningrad. Under Panyushkins leadership, the hospital witnessed substantial development, including the construction and equipping of new buildings between 1976 and 1985, where the main capacities of the hospital are concentrated today. The authors draw on Panyushkins memoir to shed light on the history of the Road Hospital, its doctors from different generations, and the experiences of Soviet medicine during the 1960s to 1990s. The authors of this article constantly refer to the materials of this book, which may be useful to clinicians as well as those who are interested in the history of domestic medicine.
The importance of the level of education as a social characteristic of the patient in the formation of his attitude to the organization of outpatient medical care
Authors: Martirosov Aram V. , Cherkasov Sergey N. , Fedyaeva Anna V. , Karailanov Mikhail G. , Arutyunyan Grigoriy B.
Published: July 2023

The significance of a patients level of education as a social characteristic in shaping their attitude toward the provision of medical care in outpatient settings has been scientifically supported. This analysis is based on primary data obtained from interviews conducted with 502 patients seeking outpatient medical care in Moscow. The main group consisted of 185 patients with secondary or specialized secondary education, while the control group comprised 273 patients with incomplete higher, higher or multiple higher education. Various approaches have been employed to assess the management system of medical care in patients with different educational backgrounds. The data reveals a correlation between the frequency of patient visits and their evaluation of the medical care system, with distinct trends observed. Patients with lower levels of education, who make more frequent visits to medical facilities, tend to provide more critical assessments of the administrative structures. The data reveals a correlation between the frequency of patient visits and their evaluation of the medical care system, with distinct trends observed. Patients with lower levels of education, who make more frequent visits to medical facilities, tend to provide more critical assessments of the administrative structures. On the contrary, patients with higher levels of education, who also visit medical organizations frequently, tend to hold a more positive view of the administrative structures. Despite both groups assigning similar overall ratings to the medical organizations providing outpatient care, patients with higher education levels tend to file more complaints specifically concerning the organization of certain departments within the polyclinic. These complaints are predominantly related to the functioning of the laboratory service, specialized specialists, and senior management within the polyclinics staff. Consequently, a patients social characteristics significantly influence their behavior and attitude toward the health care system. It should be noted that the list of social characteristics that can impact an individuals behavior and their perception of the healthcare system is extensive.
Experience with augmented reality technology in the surgical treatment of a patient with encapsulated metal foreign bodies of lower extremities
Authors: Agakhanova Maria D. , Grebenkov Vladimir G. , Rumyantsev Valery N. , Korzhuk Mikhail S. , Dymnikov Denis A. , Ivanov Vladimir M. , Smirnov Anton Yu. , Balura Oleg V. , Eselevich Roman V. , Gavrilova Anna L.
Published: July 2023

This paper presents the experience of using augmented reality (AR) technology in the surgical treatment of a patient with encapsulated foreign bodies in the lower extremities. The study aims to test a previously developed algorithm for implementing AR technology in surgery and assess its effectiveness in treating patients with encapsulated foreign bodies. The study was conducted by a multidisciplinary team, comprising the Department of Naval Surgery of the S.M. Kirov Military Medical Academy and the Technical University named after Peter the Great. The medical and technical aspects involved an AR hardware and software package, including a personal computer and Microsoft Hololens II AR glasses. An invasive fixation system was also developed, incorporating a threaded pin used as an X-ray contrast mark with a seat for attaching special markers. The clinical part of the study involved observing and subsequently removing encapsulated foreign bodies in a patient who received inpatient treatment at the clinic of the Department of Naval Surgery in October 2022. Overall, AR technology demonstrated the potential for performing minimally invasive removal of encapsulated foreign bodies in limbs. The detailed visualization provided by AR allowed for determining optimal operative access, the volume of the upcoming operation, and the exact position, skeletotopy, and syntopia of the foreign body during the preoperative stage. Consequently, various intervention options could be digitally simulated. The use of AR technology facilitated intraoperative navigation, enhancing the safety and efficiency of the operation. Thus, AR technology has proven to be a minimally invasive, safe, and effective tool in surgical treatment. However, several unresolved issues require further research.
A clinical case of a combined method for correcting irregular post-keratoplastic astigmatism in a patient with cataract
Authors: Sinitsyn Maksim V. , Pozdeyeva Nadezhda A.
Published: July 2023

Using the example of a clinical case, a clinical and functional analysis of a combined method for correcting irregular post-keratoplastic astigmatism in a patient with cataract is presented.
Patient, aged 50, complained of low vision and fog in front of the left eye during the last 3 years. For the left eye, the diagnosis was made: Irregular post-keratoplastic astigmatism of a high degree, condition after penetrating keratoplasty, posterior capsular cataract. To correct the irregular post-keratoplastic astigmatism, the patient underwent the MyoRing implantation into the corneal graft. Then, 1 year later, the patient underwent cataract phacoemulsification with a toric intraocular lens implantation for the simultaneous correction of residual corneal astigmatism. The follow-up period after phacoemulsification was 1 year. One year after the MyoRing implantation into the corneal graft, uncorrected visual acuity and corrected visual acuity increased from 0.02 to 0.05, corneal astigmatism decreased by 4.46 D and became significantly more regular. 1 month after phacoemulsification with toric intraocular lens implantation, uncorrected visual acuity increased from 0.05 to 0.8, corrected visual acuity from 0.05 to 1.0; spherical and cylindrical components of refraction amounted to 0.5 D each and did not change anymore.
The combined method of irregular post-keratoplastic astigmatism correction in a patient with cataract showed a high refractive result, stability and safety in the late postoperative period.
Transpalpebral tonometry as a priority method for intraocular pressure monitoring in corneal pathology
Authors: Petrov Sergey Y. , Filippova Olga M. , Markelova Oksana I.
Published: July 2023

BACKGROUND: Measurement of intraocular pressure in the presence of combined ophthalmic condition could determine further therapy and prognosis. However, tonometry in corneal diseases could lead to unreliable results. The search for methods for intraocular pressure measurement in these settings is a critical task intended to expand diagnostic capabilities.
AIM: Evaluation of the transpalpebral tonometry diagnostic value for intraocular pressure monitoring in patients with corneal conditions of various origin.
MATERIALS AND METHODS: Measurements of intraocular pressure were carried out in 39 patients with glaucoma and/or cataract (mean age 62.34 9.1), with corneal changes due to various ophthalmic conditions: post-traumatic scars; keratotomy scars as a result of refractive surgery; corneal defects due to ulcerative process of various etiology; corneal erosions; bullous keratopathy; deformities and leukomas after surgical treatment of pterygium or exposure to an infectious agent. Intraocular pressure measurement was carried out using several methods: palpation, using rebound and transpalpebral tonometry, in some cases tonometry was performed according to Maklakov method.
RESULTS: The averaged data were comparable: palpation; rebound tonometry 23.34 4.7 mm Hg; transpalpebral tonometry 24.27 4.7 mm Hg; and Maklakov tonometry 23.16 5.4 mm Hg. The accuracy and reproducibility of measurement results increased significantly with the improvement of skills in using tonometers.
CONCLUSIONS: Transpalpebral tonometry using TVGD-02 tonometer makes it possible to adequately assess intraocular pressure in patients with corneal pathology. The absence of contact during the implementation of technique makes it possible to recognize it as a priority when measuring intraocular pressure in certain categories of patients.
Experience of therapeutic eyelid hygiene products use in patients with anophthalmia after eyeball injury
Authors: Baranova Nadezhda A. , Senina Irina A. , Frolov Oleg A.
Published: July 2023

BACKGROUND: One of the purposes of ocular prosthetics is to prevent the progression of pathological processes in the eyelids and conjunctiva of the anophthalmic socket.
AIM: The aim of this study is to assess the effectiveness of therapeutic eyelid hygiene products: Blepharowipe, Blepharogel cleansing (Geltek-Medica, Russia), used in the late postoperative and long-term rehabilitation periods, in patients with anophthalmia who lost the eyeball as a result of an injury.
MATERIALS AND METHODS: For the study, 3 main (50 patients) and 3 corresponding control groups (50 patients) were created. The examination of patients included: complaints, medical history; biomicroscopy of the eyelids, the conjunctiva of the anophthalmic socket, and the surface of the ocular prosthesis. In the main groups, therapeutic eyelid hygiene products were used for 8 weeks in combination with regular ocular prosthesis care. In the control groups, eyelid hygiene products were not used. Assessment and analysis of the effectiveness of the products was carried out after 1, 2 and 4 weeks in group I and after 4 and 8 weeks in groups II and III based on the dynamics of patient complaints and objective examination indicators.
RESULTS: In the main groups I and II, there was a positive dynamics: normalization of the state of the eyelids and the conjunctiva of the anophthalmic socket; increasing comfort of an ocular prosthesis wear. In the main group III and in all control groups, no significant positive dynamics was noted.
CONCLUSIONS: The results of using the products included in the course of therapeutic hygiene of the eyelids: Blepharowipe, Blepharogel cleansing showed high efficiency, and give reason to recommend them in late postoperative and long-term rehabilitation periods in patients with anophthalmia.
A Note from the Editor
Authors: Raghavan K. S.
Published: July 2023

No Abstract.
Estimating the Magnitude of Completeness of Earthquake Catalogs Using a Simple Random Variable Transformation
Authors: Taroni Matteo
Published: July 2023

The estimation of the magnitude of completeness for a seismic catalog is the starting point for most of the seismological statistical analyses. It is important, in particular, for the estimation of the Gutenberg–Richter (GR) law parameters. This law corresponds to an exponential distribution of the magnitudes. The recent studies have shown that the proper method to estimate the completeness is to check the exponentiality of the data. Here, we try to improve this method using a simple random variable transformation, which makes the method more robust in the case of catalogs with magnitudes coming from exponential distributions with different parameters, that is, catalogs with different b-values of the GR law.
Future Directions in Chronic Cough
Authors: Wingfield Digby James ,   Respiratory Medicine, Immunology and Allergy, University of Manchester, Manchester, UK,   Manchester University Foundation Trust, Manchester, UK, King Jenny ,   Respiratory Medicine, Immunology and Allergy, University of Manchester, Manchester, UK,   Manchester University Foundation Trust, Manchester, UK, Smith Jaclyn ,   Respiratory Medicine, Immunology and Allergy, University of Manchester, Manchester, UK,   Manchester University Foundation Trust, Manchester, UK, Marsden Paul ,   Respiratory Medicine, Immunology and Allergy, University of Manchester, Manchester, UK,   Manchester University Foundation Trust, Manchester, UK
Published: July 2023

Introduction: Refractory/unexplained chronic cough (RUCC) is a highly prevalent debilitating condition. The characteristics of RUCC suggest neuronal excitability. The biological mechanisms leading to this in humans are uncertain but are thought to involve changes in both the peripheral and central nervous system. Efficacy of P2X purinoceptor 3 (P2X3) antagonists suggests a role for extracellular adenosine triphosphate (ATP) in RUCC. In guinea pigs, ATP release occurs in response to hypotonic saline, through a transient receptor potential cation channel subfamily V member 4 (TRPV4)−ATP−P2X3 axis. Aims: In this review we discuss data from two European Respiratory Society 2022 abstracts in RUCC, as well as current insights and future directions in chronic cough. Results: We show that hypotonic saline cough challenge, measured by maximum evoked cough response, effectively discriminates RUCC from healthy volunteers. We show that low-dose morphine is efficacious in up to 75% of patients with RUCC and that side effects, experienced in around 38% of cases, can usually be managed. Further areas: We discuss treatable traits in chronic cough, existing pharmacological management options and future antitussives.