bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Tables 1 - 8 from MicroRNAs Regulate Tumor Angiogenesis Modulated by Endothelial Progenitor Cells
Authors: Plummer Prue N. , Freeman Ruth , Taft Ryan J. , Vider Jelena , Sax Michael , Umer Brittany A. , Gao Dingcheng , Johns Christopher , Mattick John S. , Wilton Stephen D. , Ferro Vito , McMillan Nigel A.J. , Swarbrick Alexander , Mittal Vivek , Mellick Albert S.
Published: April 2023

PDF file, 194K, Table S1 EPCs cf Lineage Depleted Cells. Table S2 EPCs cf Myeloid Progenitors. Table S3 Small RNAs Regulated in Response to Tumor. Table S4 Tumor Vasculature cf Normal Vasculature. Table S5A Tumor Vasculature cf Normal Vasculature (Log2 Normalised Expression), Table S5B Tumor Vasculature cf Normal Vasculature (Log2 Normalised Expression), Table S5C Tumor Vasculature cf Normal Vasculature (Log2 Normalised Expression), following cherry exclusion. Table S7A Human Tumor Vessels/Field, Table S7B VEGF Induction of Human ECs, Table S7C Tumor-Conditioned Media Induction of Human Cell Lines. Table S8A Tube Number and Length Mouse ECs: anti-miR-10b, Table S8B Tube Number and Length Human ECs: anti-miR-10b, Table S8C Tube Number and Length Mouse ECs: anti-miR-196b, Table S8D Tube Number and Length Human ECs: anti-miR-196b, Table S8E Wound Healing Assay Mouse ECs: anti-miR-10b, Table S8F Wound Healing Human ECs: anti-miR-10b, Table S8G Wound Healing Mouse ECs: anti-miR-196b, Table S8H Wound Healing Human ECs: anti-miR-196b.
Supplementary Methods and Figure Legend from MicroRNAs Regulate Tumor Angiogenesis Modulated by Endothelial Progenitor Cells
Authors: Plummer Prue N. , Freeman Ruth , Taft Ryan J. , Vider Jelena , Sax Michael , Umer Brittany A. , Gao Dingcheng , Johns Christopher , Mattick John S. , Wilton Stephen D. , Ferro Vito , McMillan Nigel A.J. , Swarbrick Alexander , Mittal Vivek , Mellick Albert S.
Published: April 2023

PDF file, 173K.
Supplementary Figures 1-7 from TR3 Modulates Platinum Resistance in Ovarian Cancer
Authors: Wilson Andrew J. , Liu Annie Y. , Roland Joseph , Adebayo Oluwafunmilayo B. , Fletcher Sarah A. , Slaughter James C. , Saskowski Jeanette , Crispens Marta A. , Jones Howard W. , James Samuel , Fadare Oluwole , Khabele Dineo
Published: April 2023

PDF - 404K, Supplementary Figure 1. TR3 expression in normal and neoplastic ovarian epithelium. Supplementary Figure 2. TR3 expression in ovarian cancer epithelial sub-types. Supplementary Figure 3. Association of TR3 expression with clinical data in publically available databases. Supplementary Figure 4. Effects of cisplatin in normal human ovarian surface epithelial cells (HOSE). Supplementary Figure 5. Effects of cisplatin in A2780 PAR and CP20 ovarian cancer cells. Supplementary Figure 6. Effect of cisplatin on cell growth and cytotoxicity in OVCAR8 ShScr and ShTR3 cells. Supplementary Figure 7. Linkage of JNK and Akt regulation of TR3 subcellular localization to apoptotic effects of cisplatin.
Supplementary Figure 6 from Survivin-3B Potentiates Immune Escape in Cancer but Also Inhibits the Toxicity of Cancer Chemotherapy
Authors: Végran Frédérique , Mary Romain , Gibeaud Anne , Mirjolet Céline , Collin Bertrand , Oudot Alexandra , Charon-Barra Céline , Arnould Laurent , Lizard-Nacol Sarab , Boidot Romain
Published: April 2023

PDF file, 767K, S-3B protected cells from different cancer treatments.
Supplementary Table 2 from DNA Methylation-Mediated Repression of miR-886-3p Predicts Poor Outcome of Human Small Cell Lung Cancer
Authors: Cao Jianzhong , Song Yongmei , Bi Nan , Shen Jie , Liu Wenyang , Fan Jing , Sun Guogui , Tong Tong , He Jie , Shi Yuankai , Zhang Xun , Lu Ning , He Yinghua , Zhang Hongyu , Ma Kelong , Luo Xiaoying , Lv Lei , Deng Hui , Cheng Jing , Zhu Jingde , Wang Luhua , Zhan Qimin
Published: April 2023

PDF file - 48K, Primers sequences used for BSP and methylation specific PCR analyses.
Supplementary Figure 3 from Survivin-3B Potentiates Immune Escape in Cancer but Also Inhibits the Toxicity of Cancer Chemotherapy
Authors: Végran Frédérique , Mary Romain , Gibeaud Anne , Mirjolet Céline , Collin Bertrand , Oudot Alexandra , Charon-Barra Céline , Arnould Laurent , Lizard-Nacol Sarab , Boidot Romain
Published: April 2023

PDF file, 233K, Data completing Figure 3.
Supplementary Figure 2 from Survivin-3B Potentiates Immune Escape in Cancer but Also Inhibits the Toxicity of Cancer Chemotherapy
Authors: Végran Frédérique , Mary Romain , Gibeaud Anne , Mirjolet Céline , Collin Bertrand , Oudot Alexandra , Charon-Barra Céline , Arnould Laurent , Lizard-Nacol Sarab , Boidot Romain
Published: April 2023

PDF file, 959K, Representative pictures of tumors obtained in nude mice at end point for each group and data completing Figures 1 and 2.
Supplementary Figure 4 from DNA Methylation-Mediated Repression of miR-886-3p Predicts Poor Outcome of Human Small Cell Lung Cancer
Authors: Cao Jianzhong , Song Yongmei , Bi Nan , Shen Jie , Liu Wenyang , Fan Jing , Sun Guogui , Tong Tong , He Jie , Shi Yuankai , Zhang Xun , Lu Ning , He Yinghua , Zhang Hongyu , Ma Kelong , Luo Xiaoying , Lv Lei , Deng Hui , Cheng Jing , Zhu Jingde , Wang Luhua , Zhan Qimin
Published: April 2023

PDF file - 152K, Forced expression of PLK1 and TGF-β1 reversed the phenotype created by Mimic transfection in NCI-H446 cells.
Supplementary Figure 2 from Chemotherapy Acts as an Adjuvant to Convert the Tumor Microenvironment into a Highly Permissive State for Vaccination-Induced Antitumor Immunity
Authors: Kang Tae Heung , Mao Chih-Ping , Lee Sung Yong , Chen Alexander , Lee Ji-Hyun , Kim Tae Woo , Alvarez Ronald D. , Roden Richard B.S. , Pardoll Drew , Hung Chien-Fu , Wu T.-C.
Published: April 2023

PDF file - 656K, Effect of chemotherapy on HMGB1 secretion
Supplementary Methods from Caveolin-1–LRP6 Signaling Module Stimulates Aerobic Glycolysis in Prostate Cancer
Authors: Tahir Salahaldin A. , Yang Guang , Goltsov Alexei , Song Ki-Duk , Ren Chengzhen , Wang Jianxiang , Chang Wenjun , Thompson Timothy C.
Published: April 2023

PDF file - 46K, Construction of LRP6-Flag plasmid.
Supplementary Tables 1 - 2 from Activation of HIF2α in Kidney Proximal Tubule Cells Causes Abnormal Glycogen Deposition but not Tumorigenesis
Authors: Fu Leiping , Wang Gang , Shevchuk Maria M. , Nanus David M. , Gudas Lorraine J.
Published: April 2023

PDF file - 63K, Supplemental tables for GGT-HIF2αM3 transcript quantification
Supplementary Figure 1 from Downregulation of the Novel Tumor Suppressor DIRAS1 Predicts Poor Prognosis in Esophageal Squamous Cell Carcinoma
Authors: Zhu Ying-Hui , Fu Li , Chen Leilei , Qin Yan-Ru , Liu Haibo , Xie Fajun , Zeng Tingting , Dong Sui-Sui , Li Jiangchao , Li Yan , Dai Yongdong , Xie Dan , Guan Xin-Yuan
Published: April 2023

PDF file - 2668K, Supplemental Figure 1. Expression of genes located within chromosome 19p13.3 in 50 paired ESCC and non-tumor clinical samples.
Supplementary Figure 1 from Inhibition of Protein Kinase CK2 Reduces Cyp24a1 Expression and Enhances 1,25-Dihydroxyvitamin D3 Antitumor Activity in Human Prostate Cancer Cells
Authors: Luo Wei , Yu Wei-Dong , Ma Yingyu , Chernov Mikhail , Trump Donald L. , Johnson Candace S.
Published: April 2023

PDF file - 2596K, CYP24A1 mRNA expression in PC3 cell treated with TBBz and 1,25D3
Supplementary Methods from A Meta-analysis of Lung Cancer Gene Expression Identifies PTK7 as a Survival Gene in Lung Adenocarcinoma
Authors: Chen Ron , Khatri Purvesh , Mazur Pawel K. , Polin Melanie , Zheng Yanyan , Vaka Dedeepya , Hoang Chuong D. , Shrager Joseph , Xu Yue , Vicent Silvestre , Butte Atul J. , Sweet-Cordero E. Alejandro
Published: April 2023

PDF file - 60KB
Supplementary Figure 2 from MyoD Is a Tumor Suppressor Gene in Medulloblastoma
Authors: Dey Joyoti , Dubuc Adrian M. , Pedro Kyle D. , Thirstrup Derek , Mecham Brig , Northcott Paul A. , Wu Xiaochong , Shih David , Tapscott Stephen J. , LeBlanc Michael , Taylor Michael D. , Olson James M.
Published: April 2023

PDF file - 14123K, Mouse medulloblastomas with one allele of MyoD trend towards higher Ki67 index with reduction in total number of MyoD+ cells as well as cellular expression.
Supplementary Figure 1 from MyoD Is a Tumor Suppressor Gene in Medulloblastoma
Authors: Dey Joyoti , Dubuc Adrian M. , Pedro Kyle D. , Thirstrup Derek , Mecham Brig , Northcott Paul A. , Wu Xiaochong , Shih David , Tapscott Stephen J. , LeBlanc Michael , Taylor Michael D. , Olson James M.
Published: April 2023

PDF file - 25456K, Comparative analysis of MyoD +/+; SmoA2, MyoD +/-; SmoA2 and MyoD-/-; SmoA2 mice.
Supplementary Figure Legend from Personalizing the Treatment of Pediatric Medulloblastoma: Polo-like Kinase 1 as a Molecular Target in High-Risk Children
Authors: Triscott Joanna , Lee Cathy , Foster Colleen , Manoranjan Branavan , Pambid Mary Rose , Berns Rachel , Fotovati Abbas , Venugopal Chitra , O'Halloran Katrina , Narendran Aru , Hawkins Cynthia , Ramaswamy Vijay , Bouffet Eric , Taylor Michael D. , Singhal Ash , Hukin Juliette , Rassekh Rod , Yip Stephen , Northcott Paul , Singh Sheila K. , Dunham Christopher , Dunn Sandra E.
Published: April 2023

PDF file - 80K
Supplementary Figure 4 from Combined Anti-CD40 and Anti–IL-23 Monoclonal Antibody Therapy Effectively Suppresses Tumor Growth and Metastases
Authors: von Scheidt Bianca , Leung Patrick S.K. , Yong Michelle C.R. , Zhang Yu , Towne Jennifer E. , Smyth Mark J. , Teng Michele W.L.
Published: April 2023

PDF file - 76K, Time course of cytokine production by GM-BMDCs after stimulation.
Supplementary Figure Legends, Tables 1 - 2 from Genetic Suppression of Inflammation Blocks the Tumor-Promoting Effects of TGF-β in Gastric Tissue
Authors: Ota Mitsuhiko , Horiguchi Masahito , Fang Victoria , Shibahara Kotaro , Kadota Kyuichi , Loomis Cynthia , Cammer Michael , Rifkin Daniel B.
Published: April 2023

PDF file - 108KB, Supplementary Table 1. Primer List. Supplementary Table 2. Distribution of Tgfb1 and Rag2 Genes.
Supplementary Figure 1 from Targeting Akt3 Signaling in Triple-Negative Breast Cancer
Authors: Chin Y. Rebecca , Yoshida Taku , Marusyk Andriy , Beck Andrew H. , Polyak Kornelia , Toker Alex
Published: April 2023

PDF file - 164K, AKT3 Expression and Survival in TNBC.
Supplementary Figure S2 from Whole-Genome Sequencing of Asian Lung Cancers: Second-Hand Smoke Unlikely to Be Responsible for Higher Incidence of Lung Cancer among Asian Never-Smokers
Authors: Krishnan Vidhya G. , Ebert Philip J. , Ting Jason C. , Lim Elaine , Wong Swee-Seong , Teo Audrey S.M. , Yue Yong G. , Chua Hui-Hoon , Ma Xiwen , Loh Gary S.L. , Lin Yuhao , Tan Joanna H.J. , Yu Kun , Zhang Shenli , Reinhard Christoph , Tan Daniel S.W. , Peters Brock A. , Lincoln Stephen E. , Ballinger Dennis G. , Laramie Jason M. , Nilsen Geoffrey B. , Barber Thomas D. , Tan Patrick , Hillmer Axel M. , Ng Pauline C.
Published: April 2023

Percentage of somatic variants based on 6 mutation types in Asian lung cancers.
Supplementary Figure Legends from Whole-Genome Sequencing of Asian Lung Cancers: Second-Hand Smoke Unlikely to Be Responsible for Higher Incidence of Lung Cancer among Asian Never-Smokers
Authors: Krishnan Vidhya G. , Ebert Philip J. , Ting Jason C. , Lim Elaine , Wong Swee-Seong , Teo Audrey S.M. , Yue Yong G. , Chua Hui-Hoon , Ma Xiwen , Loh Gary S.L. , Lin Yuhao , Tan Joanna H.J. , Yu Kun , Zhang Shenli , Reinhard Christoph , Tan Daniel S.W. , Peters Brock A. , Lincoln Stephen E. , Ballinger Dennis G. , Laramie Jason M. , Nilsen Geoffrey B. , Barber Thomas D. , Tan Patrick , Hillmer Axel M. , Ng Pauline C.
Published: April 2023

Legend for Supplementary Figures S1-S2.
Supplementary Tables 1 - 3, Figures 1 - 7 from An Antibody–Drug Conjugate That Targets Tissue Factor Exhibits Potent Therapeutic Activity against a Broad Range of Solid Tumors
Authors: Breij Esther C.W. , de Goeij Bart E.C.G. , Verploegen Sandra , Schuurhuis Danita H. , Amirkhosravi Ali , Francis John , Miller Vibeke Breinholt , Houtkamp Mischa , Bleeker Wim K. , Satijn David , Parren Paul W.H.I.
Published: April 2023

PDF file - 166K, Supplementary Table S1: TF HuMab: target binding characteristics and inhibition of FXa generation. Supplementary Table S2: Cross-competition between TF HuMab. Supplementary Table S3: Thromboelastography: coagulation of LPS-stimulated whole blood in the presence of 20 microg/mL TF-011, TF-013 or TF-098. Supplementary Figure S1: TF HuMab inhibit TF:FVIIa-induced ERK1/2 phosphorylation. Supplementary Figure S2: TF:FVIIa-induced IL-8 production in MDA-MB-231 cells is reduced in the presence of TF HuMab. Supplementary Figure S3: Binding of TF HuMab is unaltered after conjugation with vcMMAE or mcMMAF. Supplementary Figure S4: Anti-tumor activity of TF-ADCs in the A431 and HCT-116 xenograft models. Supplementary Figure S5: Anti-tumor activity of unconjugated TF HuMab in vivo. Supplementary Figure S6: Post-paclitaxel treatment with TF-011-MMAE in PDX models. Supplementary Figure S7: Full-length blots for Figure 1C.
Supplementary Materials, Figure Legends, and Tables from Genetic Validation of the Protein Arginine Methyltransferase PRMT5 as a Candidate Therapeutic Target in Glioblastoma
Authors: Yan Fengting , Alinari Lapo , Lustberg Mark E. , Katherine Martin Ludmila , Cordero-Nieves Hector M. , Banasavadi-Siddegowda Yeshavanth , Virk Selene , Barnholtz-Sloan Jill , Bell Erica Hlavin , Wojton Jeffrey , Jacob Naduparambil K. , Chakravarti Arnab , Nowicki Michal O. , Wu Xin , Lapalombella Rosa , Datta Jharna , Yu Bo , Gordon Kate , Haseley Amy , Patton John T. , Smith Porsha L. , Ryu John , Zhang Xiaoli , Mo Xiaokui , Marcucci Guido , Nuovo Gerard , Kwon Chang-Hyuk , Byrd John C. , Chiocca E. Antonio , Li Chenglong , Sif Said , Jacob Samson , Lawler Sean , Kaur Balveen , Baiocchi Robert A.
Published: April 2023

PDF file - 636KB, Supplemental Table S1: information of the GBM lines used in this paper. Supplemental Table S2: information of the patient clinical data for Figure 1. Supplemental Table S3: Percentage of cells positive for staining with PRMT5 in spontaneous high grade astrocytoma from Mut3 strain (GFAP-cre; cisNf1-/+; P53-/-) and normal brain tissue from wild-type control mouse stained by PRMT5 and ki-67 antibody. Supplemental table S4. GBM cell line (U251) was transfected by scramble control or si-PRMT5. Affymetrix microarray genechip was performed in three independent experiments to evaluate genes up-regulated with PRMT5 silencing.
Supplementary Figure 8 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation
Authors: Lallet-Daher Hélène , Wiel Clotilde , Gitenay Delphine , Navaratnam Naveenan , Augert Arnaud , Le Calvé Benjamin , Verbeke Stéphanie , Carling David , Aubert Sébastien , Vindrieux David , Bernard David
Published: April 2023

PDF - 2383KB, PKA activation reverses the transformation blockage induced by KCNA1.
Supplementary Figure 7 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation
Authors: Lallet-Daher Hélène , Wiel Clotilde , Gitenay Delphine , Navaratnam Naveenan , Augert Arnaud , Le Calvé Benjamin , Verbeke Stéphanie , Carling David , Aubert Sébastien , Vindrieux David , Bernard David
Published: April 2023

PDF - 1285KB, PKA activation favors OIS escape.
Supplementary Figure 4 from Potassium Channel KCNA1 Modulates Oncogene-Induced Senescence and Transformation
Authors: Lallet-Daher Hélène , Wiel Clotilde , Gitenay Delphine , Navaratnam Naveenan , Augert Arnaud , Le Calvé Benjamin , Verbeke Stéphanie , Carling David , Aubert Sébastien , Vindrieux David , Bernard David
Published: April 2023

PDF - 3282K, Membrane-associated KCNA1 favors OIS hallmarks.
Supplementary Figure 5 from NDY1/KDM2B Functions as a Master Regulator of Polycomb Complexes and Controls Self-Renewal of Breast Cancer Stem Cells
Authors: Kottakis Filippos , Foltopoulou Parthena , Sanidas Ioannis , Keller Patricia , Wronski Ania , Dake Benjamin T. , Ezell Scott A. , Shen Zhu , Naber Stephen P. , Hinds Philip W. , McNiel Elizabeth , Kuperwasser Charlotte , Tsichlis Philip N.
Published: April 2023

PDF file - 145KB, Expression of exogenous NDY1/KDM2B rescues the shNDY1 phenotype.
Supplementary Figure 3 from NDY1/KDM2B Functions as a Master Regulator of Polycomb Complexes and Controls Self-Renewal of Breast Cancer Stem Cells
Authors: Kottakis Filippos , Foltopoulou Parthena , Sanidas Ioannis , Keller Patricia , Wronski Ania , Dake Benjamin T. , Ezell Scott A. , Shen Zhu , Naber Stephen P. , Hinds Philip W. , McNiel Elizabeth , Kuperwasser Charlotte , Tsichlis Philip N.
Published: April 2023

PDF file - 139KB, The knockdown of NDY1/KDM2B interferes with the replating efficiency of mammospheres from both basal and luminal mammary adenocarcinoma cell lines.
Supplementary Figure S4 from HMGB1 Enhances Immune Suppression by Facilitating the Differentiation and Suppressive Activity of Myeloid-Derived Suppressor Cells
Authors: Parker Katherine H. , Sinha Pratima , Horn Lucas A. , Clements Virginia K. , Yang Huan , Li Jianhua , Tracey Kevin J. , Ostrand-Rosenberg Suzanne
Published: April 2023

Supplementary Figure S4. Tumors from mice treated with anti-HMGB1 mAb tend to have more tumor-infiltrating CD3+ cells.
Supplementary Figure S3 from HMGB1 Enhances Immune Suppression by Facilitating the Differentiation and Suppressive Activity of Myeloid-Derived Suppressor Cells
Authors: Parker Katherine H. , Sinha Pratima , Horn Lucas A. , Clements Virginia K. , Yang Huan , Li Jianhua , Tracey Kevin J. , Ostrand-Rosenberg Suzanne
Published: April 2023

Supplementary Figure S3. HMGB1 produced by tumor cells promotes tumor growth and metastasis.
Supplementary Tables 1 - 4 from Activation of the NOTCH Pathway in Head and Neck Cancer
Authors: Sun Wenyue , Gaykalova Daria A. , Ochs Michael F. , Mambo Elizabeth , Arnaoutakis Demetri , Liu Yan , Loyo Myriam , Agrawal Nishant , Howard Jason , Li Ryan , Ahn Sun , Fertig Elana , Sidransky David , Houghton Jeffery , Buddavarapu Kalyan , Sanford Tiffany , Choudhary Ashish , Darden Will , Adai Alex , Latham Gary , Bishop Justin , Sharma Rajni , Westra William H. , Hennessey Patrick , Chung Christine H. , Califano Joseph A.
Published: April 2023

PDF file - 88K, Supplementary Table I. Baseline characteristics of the HNSCC patients for microarray analysis. Supplementary Table II. Short Tandem Repeat Profile of the 2 HNSCC Cell Lines. Supplementary Table III. NOTCH Signaling Pathway Genes assigned in KEGG pathway database and shown on expression microarrays. Supplementary Table IV. Summary of the mRNA levels of NOTCH signaling pathway genes in the cohort of 44 HNSCC tumors and 25 normal mucosas measured by Affymetrix expression array.
Supplementary Methods from Activation of the NOTCH Pathway in Head and Neck Cancer
Authors: Sun Wenyue , Gaykalova Daria A. , Ochs Michael F. , Mambo Elizabeth , Arnaoutakis Demetri , Liu Yan , Loyo Myriam , Agrawal Nishant , Howard Jason , Li Ryan , Ahn Sun , Fertig Elana , Sidransky David , Houghton Jeffery , Buddavarapu Kalyan , Sanford Tiffany , Choudhary Ashish , Darden Will , Adai Alex , Latham Gary , Bishop Justin , Sharma Rajni , Westra William H. , Hennessey Patrick , Chung Christine H. , Califano Joseph A.
Published: April 2023

PDF file - 111K
Supplementary Figure 5 from HIC1 Silencing in Triple-Negative Breast Cancer Drives Progression through Misregulation of LCN2
Authors: Cheng Guangcun , Sun Xueqing , Wang Jinglong , Xiao Gang , Wang Xiumin , Fan Xuemei , Zu Lidong , Hao Mingang , Qu Qing , Mao Yan , Xue Yunjing , Wang Jianhua
Published: April 2023

PDF file - 570K, LCN2 promotes lung metastasis in balb/c nude mice.
Video S4 from The NADH Oxidase ENOX1, a Critical Mediator of Endothelial Cell Radiosensitization, Is Crucial for Vascular Development
Authors: Venkateswaran Amudhan , Sekhar Konjeti R. , Levic Daniel S. , Melville David B. , Clark Travis A. , Rybski Witold M. , Walsh Alexandra J. , Skala Melissa C. , Crooks Peter A. , Knapik Ela W. , Freeman Michael L.
Published: April 2023

AVI file 79712K, circulation in embryo treated with VJ11
Supplementary Figure 3 from HIC1 Silencing in Triple-Negative Breast Cancer Drives Progression through Misregulation of LCN2
Authors: Cheng Guangcun , Sun Xueqing , Wang Jinglong , Xiao Gang , Wang Xiumin , Fan Xuemei , Zu Lidong , Hao Mingang , Qu Qing , Mao Yan , Xue Yunjing , Wang Jianhua
Published: April 2023

PDF file - 141K, HIC1 and LCN2 do not affect epithelial-mesenchymal transition (EMT).
Video S3 from The NADH Oxidase ENOX1, a Critical Mediator of Endothelial Cell Radiosensitization, Is Crucial for Vascular Development
Authors: Venkateswaran Amudhan , Sekhar Konjeti R. , Levic Daniel S. , Melville David B. , Clark Travis A. , Rybski Witold M. , Walsh Alexandra J. , Skala Melissa C. , Crooks Peter A. , Knapik Ela W. , Freeman Michael L.
Published: April 2023

AVI file 50842K, circulation in solvent control embryo
Video S1 from The NADH Oxidase ENOX1, a Critical Mediator of Endothelial Cell Radiosensitization, Is Crucial for Vascular Development
Authors: Venkateswaran Amudhan , Sekhar Konjeti R. , Levic Daniel S. , Melville David B. , Clark Travis A. , Rybski Witold M. , Walsh Alexandra J. , Skala Melissa C. , Crooks Peter A. , Knapik Ela W. , Freeman Michael L.
Published: April 2023

Video S1 MOV file 4944K, circulation in control morphant
Supplementary Table 2 from Acquired Expression of NFATc1 Downregulates E-Cadherin and Promotes Cancer Cell Invasion
Authors: Oikawa Tsukasa , Nakamura Atsuko , Onishi Nobuyuki , Yamada Taketo , Matsuo Koichi , Saya Hideyuki
Published: April 2023

XLS file, 30K, List of a primer pair used for ChIP assay.
Supplementary Table 1 from Acquired Expression of NFATc1 Downregulates E-Cadherin and Promotes Cancer Cell Invasion
Authors: Oikawa Tsukasa , Nakamura Atsuko , Onishi Nobuyuki , Yamada Taketo , Matsuo Koichi , Saya Hideyuki
Published: April 2023

XLS file, 25232K, List of genes.
Supplementary Figure Legends from Acquired Expression of NFATc1 Downregulates E-Cadherin and Promotes Cancer Cell Invasion
Authors: Oikawa Tsukasa , Nakamura Atsuko , Onishi Nobuyuki , Yamada Taketo , Matsuo Koichi , Saya Hideyuki
Published: April 2023

PDF file, 83K.
Dataset S4 from The NADH Oxidase ENOX1, a Critical Mediator of Endothelial Cell Radiosensitization, Is Crucial for Vascular Development
Authors: Venkateswaran Amudhan , Sekhar Konjeti R. , Levic Daniel S. , Melville David B. , Clark Travis A. , Rybski Witold M. , Walsh Alexandra J. , Skala Melissa C. , Crooks Peter A. , Knapik Ela W. , Freeman Michael L.
Published: April 2023

XLSX file 11K, Expression of transcription factors and membrane receptors critical for vascular development
Dataset S3 from The NADH Oxidase ENOX1, a Critical Mediator of Endothelial Cell Radiosensitization, Is Crucial for Vascular Development
Authors: Venkateswaran Amudhan , Sekhar Konjeti R. , Levic Daniel S. , Melville David B. , Clark Travis A. , Rybski Witold M. , Walsh Alexandra J. , Skala Melissa C. , Crooks Peter A. , Knapik Ela W. , Freeman Michael L.
Published: April 2023

XLSX file 30K, Up-regulated genes assigned to GO:0008152 metabolic processing
DataSet S1 from The NADH Oxidase ENOX1, a Critical Mediator of Endothelial Cell Radiosensitization, Is Crucial for Vascular Development
Authors: Venkateswaran Amudhan , Sekhar Konjeti R. , Levic Daniel S. , Melville David B. , Clark Travis A. , Rybski Witold M. , Walsh Alexandra J. , Skala Melissa C. , Crooks Peter A. , Knapik Ela W. , Freeman Michael L.
Published: April 2023

XLSX file 150K, Genes that exhibit a 2 fold or greater change in expression - P less than 0.05
Data Supplement from Osteopontin Shapes Immunosuppression in the Metastatic Niche
Authors: Sangaletti Sabina , Tripodo Claudio , Sandri Sara , Torselli Ilaria , Vitali Caterina , Ratti Chiara , Botti Laura , Burocchi Alessia , Porcasi Rossana , Tomirotti Andrea , Colombo Mario P. , Chiodoni Claudia
Published: April 2023

Supplemental Figure 1. OPN-silencing in tumor cells affects their migratory and invasive capacity in vitro and metastatic potential in vivo.
Data Supplement from Osteopontin Shapes Immunosuppression in the Metastatic Niche
Authors: Sangaletti Sabina , Tripodo Claudio , Sandri Sara , Torselli Ilaria , Vitali Caterina , Ratti Chiara , Botti Laura , Burocchi Alessia , Porcasi Rossana , Tomirotti Andrea , Colombo Mario P. , Chiodoni Claudia
Published: April 2023

Supplemental Figure 2. MDSC subsets in the lungs of naive mice and in vitro suppressive activity of tumor-bearers' MDSC.
Supplementary Table 2 from UTX and MLL4 Coordinately Regulate Transcriptional Programs for Cell Proliferation and Invasiveness in Breast Cancer Cells
Authors: Kim Jae-Hwan , Sharma Amrish , Dhar Shilpa S. , Lee Sung-Hun , Gu Bingnan , Chan Chia-Hsin , Lin Hui-Kuan , Lee Min Gyu
Published: April 2023

PDF file - 61KB, Statistically significant Gene Ontology (GO) terms of genes co- downregulated by UTX and MLL4 knockdown.
Supplementary Figure 2 from RAE1 Ligands for the NKG2D Receptor Are Regulated by STING-Dependent DNA Sensor Pathways in Lymphoma
Authors: Lam Adeline R. , Le Bert Nina , Ho Samantha S.W. , Shen Yu J. , Tang Melissa L.F. , Xiong Gordon M. , Croxford J. Ludovic , Koo Christine X. , Ishii Ken J. , Akira Shizuo , Raulet David H. , Gasser Stephan
Published: April 2023

PDF file - 155K, Phosphorylation of TBK1S172 in response to DNA damage.
Supplementary Figure 1 from RAE1 Ligands for the NKG2D Receptor Are Regulated by STING-Dependent DNA Sensor Pathways in Lymphoma
Authors: Lam Adeline R. , Le Bert Nina , Ho Samantha S.W. , Shen Yu J. , Tang Melissa L.F. , Xiong Gordon M. , Croxford J. Ludovic , Koo Christine X. , Ishii Ken J. , Akira Shizuo , Raulet David H. , Gasser Stephan
Published: April 2023

PDF file - 164K, Efficiencies of Zbp1, Rig-I, Sting, Tbk1, and Irf3 shRNA-mediated knockdown in BC2 cells.
Supplementary Figure 4 from UTX and MLL4 Coordinately Regulate Transcriptional Programs for Cell Proliferation and Invasiveness in Breast Cancer Cells
Authors: Kim Jae-Hwan , Sharma Amrish , Dhar Shilpa S. , Lee Sung-Hun , Gu Bingnan , Chan Chia-Hsin , Lin Hui-Kuan , Lee Min Gyu
Published: April 2023

PDF file - 48KB, Two different MLL4 antibodies confirmed that MLL4 is recruited to MMP-9, MMP-11, and Six1 genes.
Supplementary Figure 1 from UTX and MLL4 Coordinately Regulate Transcriptional Programs for Cell Proliferation and Invasiveness in Breast Cancer Cells
Authors: Kim Jae-Hwan , Sharma Amrish , Dhar Shilpa S. , Lee Sung-Hun , Gu Bingnan , Chan Chia-Hsin , Lin Hui-Kuan , Lee Min Gyu
Published: April 2023

PDF file - 155KB, UTX knockdown had no effect on cell migration, whereas MLL4 depletion moderately decreased cell migration.
Supplementary Figure 5 from CRR9/CLPTM1L Regulates Cell Survival Signaling and Is Required for Ras Transformation and Lung Tumorigenesis
Authors: James Michael A. , Vikis Haris G. , Tate Everett , Rymaszewski Amy L. , You Ming
Published: April 2023

PDF file - 92K, TERT Depletion in Mouse Cells.
Supplementary Figure 3 from Identification of a Cyclin D1 Network in Prostate Cancer That Antagonizes Epithelial–Mesenchymal Restraint
Authors: Ju Xiaoming , Casimiro Mathew C. , Gormley Michael , Meng Hui , Jiao Xuanmao , Katiyar Sanjay , Crosariol Marco , Chen Ke , Wang Min , Quong Andrew A. , Lisanti Michael P. , Ertel Adam , Pestell Richard G.
Published: April 2023

PDF file - 208K, DHT regulated gene pathways in cyclin D1+/+ and cyclin D1-/- mouse prostates.
Supplementary Materials and Methods, Figure Legends from Curative Properties of Noninternalizing Antibody–Drug Conjugates Based on Maytansinoids
Authors: Perrino Elena , Steiner Martina , Krall Nikolaus , Bernardes Gonçalo J.L. , Pretto Francesca , Casi Giulio , Neri Dario
Published: April 2023

PDF file - 162KB
Supplemetary Video S3 from Snail1-Expressing Fibroblasts in the Tumor Microenvironment Display Mechanical Properties That Support Metastasis
Authors: Stanisavljevic Jelena , Loubat-Casanovas Jordina , Herrera Mercedes , Luque Tomás , Peña Raúl , Lluch Ana , Albanell Joan , Bonilla Félix , Rovira Ana , Peña Cristina , Navajas Daniel , Rojo Federico , García de Herreros Antonio , Baulida Josep
Published: April 2023

Video S3. MDA-MB231 cells on 3D-ECM generated by KO MEFs.
Supplementary Data Figure Legends from CD38 in Hairy Cell Leukemia Is a Marker of Poor Prognosis and a New Target for Therapy
Authors: Poret Nicolas , Fu Qiangwei , Guihard Soizic , Cheok Meyling , Miller Katie , Zeng Gordon , Quesnel Bruno , Troussard Xavier , Galiègue-Zouitina Sylvie , Shelley Carl Simon
Published: April 2023

Supplementary Data Legends to Figures 1-4
Supplemental Figure S3 from PD-1/SHP-2 Inhibits Tc1/Th1 Phenotypic Responses and the Activation of T Cells in the Tumor Microenvironment
Authors: Li Jing , Jie Hyun-Bae , Lei Yu , Gildener-Leapman Neil , Trivedi Sumita , Green Tony , Kane Lawrence P. , Ferris Robert L.
Published: April 2023

Supplemental Figure S3. Fusaruside triggers the tyrosine phosphorylation of SHP-2 in human T lymphocytes from PBMC.
Supplementary Figures S1-S5 and Tables S1-S3 from Snail1-Expressing Fibroblasts in the Tumor Microenvironment Display Mechanical Properties That Support Metastasis
Authors: Stanisavljevic Jelena , Loubat-Casanovas Jordina , Herrera Mercedes , Luque Tomás , Peña Raúl , Lluch Ana , Albanell Joan , Bonilla Félix , Rovira Ana , Peña Cristina , Navajas Daniel , Rojo Federico , García de Herreros Antonio , Baulida Josep
Published: April 2023

Supplementary Figure S1. TGF beta remodels the ECM generated by mesenchymal stem and 1BR3G cells in a Snail1-dependent manner. Supplementary Figure S2. Cell Commitment is Modulated by Fibroblast-derived Matrices in a Snail1-dependent Manner. Supplementary Figure S3. TGF beta controls focal contacts in a Snail1-dependent manner. Supplementary Figure S4. TGF beta regulates N-cadherin intercellular contacts in a Snail1-dependent manner. Supplementary Figure S5. Alignment of MEFs bo-cultured with CAFs. Supplementary Table S1. Baseline Characteristics According to Snail1 Expression in the Stroma Supplementary Table S2. Overall Survival Analysis in Patients with Snail1 Expression in Stroma Supplementary Table S3. Antibodies Used for Protein Analysis
Supplemental Figure Legends from PD-1/SHP-2 Inhibits Tc1/Th1 Phenotypic Responses and the Activation of T Cells in the Tumor Microenvironment
Authors: Li Jing , Jie Hyun-Bae , Lei Yu , Gildener-Leapman Neil , Trivedi Sumita , Green Tony , Kane Lawrence P. , Ferris Robert L.
Published: April 2023

Supplemental Figure Legends. Legends for Supplemental Figures S1-S3.
Supplementary Table S1 from Perivascular M2 Macrophages Stimulate Tumor Relapse after Chemotherapy
Authors: Hughes Russell , Qian Bin-Zhi , Rowan Charlotte , Muthana Munitta , Keklikoglou Ioanna , Olson Oakley C. , Tazzyman Simon , Danson Sarah , Addison Christina , Clemons Mark , Gonzalez-Angulo Ana Maria , Joyce Johanna A. , De Palma Michele , Pollard Jeffrey W. , Lewis Claire E.
Published: April 2023

Antibody Details
Supplementary Figures S1-S7 from Perivascular M2 Macrophages Stimulate Tumor Relapse after Chemotherapy
Authors: Hughes Russell , Qian Bin-Zhi , Rowan Charlotte , Muthana Munitta , Keklikoglou Ioanna , Olson Oakley C. , Tazzyman Simon , Danson Sarah , Addison Christina , Clemons Mark , Gonzalez-Angulo Ana Maria , Joyce Johanna A. , De Palma Michele , Pollard Jeffrey W. , Lewis Claire E.
Published: April 2023

Effects of various cytotoxic agents on TAM accumulation in three mouse tumor models (S1); Further Characterization of MRC1+ TAMs in mouse tumors (S2); VEGFA lmmunofluorescence in control and CTX-treated LLC1 tumors (S3); Role of hypoxic (ie. HIF-expressing) TAMs in relapse of LLC1 tumors after CTX (S4); Effect of CXCR4 blockade on various tumor parameters in CTX-treated LLC1 tumors (S5); Co-localization of HIFs 1 and 2, but not CXCL12 or HO-1, with hypoxia in LLC1s (S6); Effect of CXCR4 blockade on the longer-term re-growth kinetics of primary and metastatic LLC1s (S7).
Supplemental Methods from Imaging Active Urokinase Plasminogen Activator in Prostate Cancer
Authors: LeBeau Aaron M. , Sevillano Natalia , Markham Kate , Winter Michael B. , Murphy Stephanie T. , Hostetter Daniel R. , West James , Lowman Henry , Craik Charles S. , VanBrocklin Henry F.
Published: April 2023

Supplemental Methods. Description of additional methods and procedures used in the study.
Supplemental Figures S1-S6 from Imaging Active Urokinase Plasminogen Activator in Prostate Cancer
Authors: LeBeau Aaron M. , Sevillano Natalia , Markham Kate , Winter Michael B. , Murphy Stephanie T. , Hostetter Daniel R. , West James , Lowman Henry , Craik Charles S. , VanBrocklin Henry F.
Published: April 2023

Supplemental Figures S1-S6. U33 Fab Sequence (S1); Inhibition constant calculation of U33 Fab (S2); U33 does not bind to the uPA-PAI1 complex (S3); Selectivity of U33 IgG for active uPA versus inactive uPA (S4); Dependence of U33 IgG binding on an accessible uPA active site (S5); Selectivity of U33 IgG for human uPA compared to highly related serine proteases (S6).
Supplementary Figure 3 from Genetic Mutation of p53 and Suppression of the miR-17∼92 Cluster Are Synthetic Lethal in Non–Small Cell Lung Cancer due to Upregulation of Vitamin D Signaling
Authors: Borkowski Robert , Du Liqin , Zhao Zhenze , McMillan Elizabeth , Kosti Adam , Yang Chin-Rang , Suraokar Milind , Wistuba Ignacio I. , Gazdar Adi F. , Minna John D. , White Michael A. , Pertsemlidis Alexander
Published: April 2023

Supplementary Figure 3. Transcriptional profiling of HBEC30KT and HBEC30KT-shTP53 identifies context-dependent de-repression of the miR-17~92 targetome after p53 loss driven by target genes of the miR-17-92 polycistron.
Supplementary Figure 1 from Genetic Mutation of p53 and Suppression of the miR-17∼92 Cluster Are Synthetic Lethal in Non–Small Cell Lung Cancer due to Upregulation of Vitamin D Signaling
Authors: Borkowski Robert , Du Liqin , Zhao Zhenze , McMillan Elizabeth , Kosti Adam , Yang Chin-Rang , Suraokar Milind , Wistuba Ignacio I. , Gazdar Adi F. , Minna John D. , White Michael A. , Pertsemlidis Alexander
Published: April 2023

Supplementary Figure 1. Activity of miR-92a related inhibitors.
Supplementary Figure S7 from Targeting of Runx2 by miR-135 and miR-203 Impairs Progression of Breast Cancer and Metastatic Bone Disease
Authors: Taipaleenmäki Hanna , Browne Gillian , Akech Jacqueline , Zustin Jozef , van Wijnen Andre J. , Stein Janet L. , Hesse Eric , Stein Gary S. , Lian Jane B.
Published: April 2023

Supplementary Figure S7. miR-135 and miR-203 reduce breast cancer metastasis to lung.
Supplemental Figure 7 from Tumor Radiosensitization by Monomethyl Auristatin E: Mechanism of Action and Targeted Delivery
Authors: Buckel Lisa , Savariar Elamprakash N. , Crisp Jessica L. , Jones Karra A. , Hicks Angel M. , Scanderbeg Daniel J. , Nguyen Quyen T. , Sicklick Jason K. , Lowy Andrew M. , Tsien Roger Y. , Advani Sunil J.
Published: April 2023

Schematic model of therapeutic strategy utilizing tumor targeted MMAE delivery with ACPP.
Supplementary figure 3 from Ceacam1L Modulates STAT3 Signaling to Control the Proliferation of Glioblastoma-Initiating Cells
Authors: Kaneko Sadahiro , Nakatani Yuka , Takezaki Tatsuya , Hide Takuichiro , Yamashita Daisuke , Ohtsu Naoki , Ohnishi Takanori , Terasaka Shunsuke , Houkin Kiyohiro , Kondo Toru
Published: April 2023

Supplementary figure 3. The Ceacam1L/STAT3 axis regulated the expression of stemness-related genes in NSCL61s
Supplemental Table S1 from miR-339-3p Is a Tumor Suppressor in Melanoma
Authors: Weber Claudia E.M. , Luo Chonglin , Hotz-Wagenblatt Agnes , Gardyan Adriane , Kordaß Theresa , Holland-Letz Tim , Osen Wolfram , Eichmüller Stefan B.
Published: April 2023

Characterization of melanoma cell lines.
Supplementary Table S2 from Lysophosphatidic Acid Receptor LPAR6 Supports the Tumorigenicity of Hepatocellular Carcinoma
Authors: Mazzocca Antonio , Dituri Francesco , De Santis Flavia , Filannino Addolorata , Lopane Chiara , Betz Regina C. , Li Ying-Yi , Mukaida Naofumi , Winter Peter , Tortorella Cosimo , Giannelli Gianluigi , Sabbà Carlo
Published: April 2023

List of genes down-regulated in LPAR6 knocked down cells.
Supplementary Figures S1-S7 from Lysophosphatidic Acid Receptor LPAR6 Supports the Tumorigenicity of Hepatocellular Carcinoma
Authors: Mazzocca Antonio , Dituri Francesco , De Santis Flavia , Filannino Addolorata , Lopane Chiara , Betz Regina C. , Li Ying-Yi , Mukaida Naofumi , Winter Peter , Tortorella Cosimo , Giannelli Gianluigi , Sabbà Carlo
Published: April 2023

Expression of LPAR1-5 mRNA levels in peritumoral and HCC cell lines (S1); Cell cycle analysis of LPAR6-knocked-down cells versus controls (S2); Absence of apoptosis in stably LPAR6-knocked-down cells (S3); LPAR6 knockdown impairs HCC migration and actin organization but not cells adhesion (S4); Ectopic expression of LPAR6 in human hepatocarcinoma cell line HLE (S5); LPAR6 knockdown affects the gene expression profile in HCC cells (S6); The PIM3 inhibitor, SGI-1776 decreases tumor growth in vivo and in vitro (S7).
Supplementary Figure 1 from Identification of a Functional SNP in the 3′UTR of CXCR2 That Is Associated with Reduced Risk of Lung Cancer
Authors: Ryan Bríd M. , Robles Ana I. , McClary Andrew C. , Haznadar Majda , Bowman Elise D. , Pine Sharon R. , Brown Derek , Khan Mohammed , Shiraishi Kouya , Kohno Takashi , Okayama Hirokazu , Modali Ramakrishna , Yokota Jun , Harris Curtis C.
Published: April 2023

Predicted modulation of miR-138-1* binding to CXCR2 mRNA by rs1126579.
Supplementary Methods from Histone Deacetylase Inhibitors Repress Tumoral Expression of the Proinvasive Factor RUNX2
Authors: Sancisi Valentina , Gandolfi Greta , Ambrosetti Davide Carlo , Ciarrocchi Alessia
Published: April 2023

Supplementary Methods. Description of additional methods and procedures used in the study.
Supplementary Methods and References from Stem Cell Transplantation Reverses Chemotherapy-Induced Cognitive Dysfunction
Authors: Acharya Munjal M. , Martirosian Vahan , Chmielewski Nicole N. , Hanna Nevine , Tran Katherine K. , Liao Alicia C. , Christie Lori-Ann , Parihar Vipan K. , Limoli Charles L.
Published: April 2023

Description of additional methods and procedures used in the study. Also includes Supplementary References.
Supplementary Figure S4 from High-Mobility Group Box 1 Promotes Hepatocellular Carcinoma Progression through miR-21–Mediated Matrix Metalloproteinase Activity
Authors: Chen Man , Liu Yao , Varley Patrick , Chang Ying , He Xing-xing , Huang Hai , Tang Daolin , Lotze Michael T. , Lin Jusheng , Tsung Allan
Published: April 2023

Supplementary Figure S4. The HMGB1-IL6-STAT3-miR-21 axis promotes HCC tumor progression.
Supplementary Figure S3 from High-Mobility Group Box 1 Promotes Hepatocellular Carcinoma Progression through miR-21–Mediated Matrix Metalloproteinase Activity
Authors: Chen Man , Liu Yao , Varley Patrick , Chang Ying , He Xing-xing , Huang Hai , Tang Daolin , Lotze Michael T. , Lin Jusheng , Tsung Allan
Published: April 2023

Supplementary Figure S3. In vivo imaging of MMP activity and tumor growth.
Supplementary Figure S1 from High-Mobility Group Box 1 Promotes Hepatocellular Carcinoma Progression through miR-21–Mediated Matrix Metalloproteinase Activity
Authors: Chen Man , Liu Yao , Varley Patrick , Chang Ying , He Xing-xing , Huang Hai , Tang Daolin , Lotze Michael T. , Lin Jusheng , Tsung Allan
Published: April 2023

Supplementary Figure S1. Mir-21 is stimulated by HMGB1 through IL-6/ stat3 pathway in HepG2 cells.
Supplementayr Figure 6 from TLR2 Limits Development of Hepatocellular Carcinoma by Reducing IL18-Mediated Immunosuppression
Authors: Li Shinan , Sun Rui , Chen Yongyan , Wei Haiming , Tian Zhigang
Published: April 2023

S. Fig. 6. Caspase-8 expression after DEN/Pam3CSK4 and shcaspase-8 treatment.
Supplementary Table 1 from TLR2 Limits Development of Hepatocellular Carcinoma by Reducing IL18-Mediated Immunosuppression
Authors: Li Shinan , Sun Rui , Chen Yongyan , Wei Haiming , Tian Zhigang
Published: April 2023

Primer information.
Supplementary Figure 7 from TLR2 Limits Development of Hepatocellular Carcinoma by Reducing IL18-Mediated Immunosuppression
Authors: Li Shinan , Sun Rui , Chen Yongyan , Wei Haiming , Tian Zhigang
Published: April 2023

S. Fig. 7. Pam3CSK4 stimulation reduces MDSC number.
SUPPLEMENTARY TABLE S1. from Loss of Tet1-Associated 5-Hydroxymethylcytosine Is Concomitant with Aberrant Promoter Hypermethylation in Liver Cancer
Authors: Thomson John P. , Ottaviano Raffaele , Unterberger Elif B. , Lempiäinen Harri , Muller Arne , Terranova Remi , Illingworth Robert S. , Webb Shaun , Kerr Alastair R.W. , Lyall Marcus J. , Drake Amanda J. , Wolf C. Roland , Moggs Jonathan G. , Schwarz Michael , Meehan Richard R.
Published: April 2023

List of genes exhibiting loss of promoter core 5hmC and gain of 5mC in PB driven liver tumours
Supplementary Figure 1 from TLR2 Limits Development of Hepatocellular Carcinoma by Reducing IL18-Mediated Immunosuppression
Authors: Li Shinan , Sun Rui , Chen Yongyan , Wei Haiming , Tian Zhigang
Published: April 2023

S. Fig. 1. CD8+ T cell function is impaired in Tlr2-/- mice.
Supplementary Figure S5 from CCL9 Induced by TGFβ Signaling in Myeloid Cells Enhances Tumor Cell Survival in the Premetastatic Organ
Authors: Yan Hangyi H. , Jiang Jian , Pang Yanli , Achyut B.R. , Lizardo Michael , Liang Xinhua , Hunter Kent , Khanna Chand , Hollander Christine , Yang Li
Published: April 2023

CCL9 regulation by TGFβ-p38 pathway.
Supplementary Table 2 from Wnt/β-Catenin Small-Molecule Inhibitor CWP232228 Preferentially Inhibits the Growth of Breast Cancer Stem-like Cells
Authors: Jang Gyu-Beom , Hong In-Sun , Kim Ran-Ju , Lee Su-Youn , Park Se-Jin , Lee Eun-Sook , Park Jung Hyuck , Yun Chi-Ho , Chung Jae-Uk , Lee Kyoung-June , Lee Hwa-Yong , Nam Jeong-Seok
Published: April 2023

The extreme limiting dilution(ELDA)assay.
Supplementary Figure Legends from Wnt/β-Catenin Small-Molecule Inhibitor CWP232228 Preferentially Inhibits the Growth of Breast Cancer Stem-like Cells
Authors: Jang Gyu-Beom , Hong In-Sun , Kim Ran-Ju , Lee Su-Youn , Park Se-Jin , Lee Eun-Sook , Park Jung Hyuck , Yun Chi-Ho , Chung Jae-Uk , Lee Kyoung-June , Lee Hwa-Yong , Nam Jeong-Seok
Published: April 2023

Supplementary figure legends
Dataset S1 from Nitric Oxide Regulates Gene Expression in Cancers by Controlling Histone Posttranslational Modifications
Authors: Vasudevan Divya , Hickok Jason R. , Bovee Rhea C. , Pham Vy , Mantell Lin L. , Bahroos Neil , Kanabar Pinal , Cao Xing-Jun , Maienschein-Cline Mark , Garcia Benjamin A. , Thomas Douglas D.
Published: April 2023

GO terms associated with ÃƒÂ¢Ã‹â€ Ã¢â€žÂ¢NO-regulated genes
Supplementary Figure 5 from Wnt/β-Catenin Small-Molecule Inhibitor CWP232228 Preferentially Inhibits the Growth of Breast Cancer Stem-like Cells
Authors: Jang Gyu-Beom , Hong In-Sun , Kim Ran-Ju , Lee Su-Youn , Park Se-Jin , Lee Eun-Sook , Park Jung Hyuck , Yun Chi-Ho , Chung Jae-Uk , Lee Kyoung-June , Lee Hwa-Yong , Nam Jeong-Seok
Published: April 2023

The comparison of CWP232228 activities with another well-known small molecule inhibitor.
Supplementary Figures S1-19 and legends from Hypoxia Drives Breast Tumor Malignancy through a TET–TNFα–p38–MAPK Signaling Axis
Authors: Wu Min-Zu , Chen Su-Feng , Nieh Shin , Benner Christopher , Ger Luo-Ping , Jan Chia-Ing , Ma Li , Chen Chien-Hung , Hishida Tomoaki , Chang Hong-Tai , Lin Yaoh-Shiang , Montserrat Nuria , Gascon Pedro , Sancho-Martinez Ignacio , Izpisua Belmonte Juan Carlos
Published: April 2023

Supplementary Figures S1-19 and legends. Figure S1: Overexpression of HIF-1α enhances BTIC characteristics. Figure S2: Characterizations of isolated BTICs by different parameters. Figure S3: The expression of TET1 and TET3 is upregulated by hypoxia. Figure S4: HIF-1α binding to TET1 and TET3 gene promoter in HIF-1α overexpressing cells. Figure S5: Knockdown of TET diminishes hypoxia induced activation of stemness related genes in breast cancer cell lines. Figure S6: Knockdown of TET1/3 represses tumorigenicity of isolated BTICs in vivo. Figure S7: Isotype control for IHC analysis. Figure S8: Gene specific changes in 5hmC level and TET proteins binding in hypoxic, HIF-1α overexpressing cells and isolated BTICs. Figure S9: Starvation is unable to affect the levels of 5hmC on the genome regions of TNFα gene and TNFα gene expression. Figure S10: TET proteins are essential for hypoxia activated TNFα-p38-MAPK signaling. Figure S11: TET proteins are required for hypoxia-induced 5hmC change on the genome regions of the TNFα gene. Figure S12: The enzymatic activity of TET proteins is required for establishing 5hmC signature upon hypoxia. Figure S13: The enzymatic activity of TET proteins is required for activation of TNFα-p38-MAPK signaling upon hypoxia. Figure S14: Protein-protein interaction between TET1 and TET3 in hypoxic cells and isolated BTICs. Figure S15: Co-occupancy of TET1 and TET3 on genome regions of the TNFα gene. Figure S16: Suppression of p38-MAPK signaling reduces BTIC properties. Figure S17: Certain downstream targets of TNFα-p38-MAPK signaling are regulated by hypoxia/TET. Figure S18: The levels of 5hmC and the bindings of TET proteins at pluripotent loci upon hypoxia. Figure S19: The landscape for 5hmC level and TET proteins binding on pluripotent loci upon hypoxia.
Supplementary Methods, References, Figure Legends from Microenvironment-Modulated Metastatic CD133+/CXCR4+/EpCAM− Lung Cancer–Initiating Cells Sustain Tumor Dissemination and Correlate with Poor Prognosis
Authors: Bertolini Giulia , D'Amico Lucia , Moro Massimo , Landoni Elena , Perego Paola , Miceli Rosalba , Gatti Laura , Andriani Francesca , Wong Donald , Caserini Roberto , Tortoreto Monica , Milione Massimo , Ferracini Riccardo , Mariani Luigi , Pastorino Ugo , Roato Ilaria , Sozzi Gabriella , Roz Luca
Published: April 2023

Supplementary Methods, References, Figure Legends from Microenvironment-Modulated Metastatic CD133+/CXCR4+/EpCAM− Lung Cancer–Initiating Cells Sustain Tumor Dissemination and Correlate with Poor Prognosis
Supplementary Table S1 from NRF2 Intensifies Host Defense Systems to Prevent Lung Carcinogenesis, but After Tumor Initiation Accelerates Malignant Cell Growth
Authors: Satoh Hironori , Moriguchi Takashi , Saigusa Daisuke , Baird Liam , Yu Lei , Rokutan Hirofumi , Igarashi Keiko , Ebina Masahito , Shibata Tatsuhiro , Yamamoto Masayuki
Published: April 2023

Nrf2-target genes showing differential expression patterns between the Keap1-wt and the Keap1-kd tumors.
Supplementary Figure 2 from Adaptive Upregulation of EGFR Limits Attenuation of Tumor Growth by Neutralizing IL6 Antibodies, with Implications for Combined Therapy in Ovarian Cancer
Authors: Milagre Carla S. , Gopinathan Ganga , Everitt Gemma , Thompson Richard G. , Kulbe Hagen , Zhong Haihong , Hollingsworth Robert E. , Grose Richard , Bowtell David D.L. , Hochhauser Daniel , Balkwill Frances R.
Published: April 2023

Supplementary Figure 2. pSTAT3, pErbB-1 and pERK quantification.
Supplementary Figure 1 from Adaptive Upregulation of EGFR Limits Attenuation of Tumor Growth by Neutralizing IL6 Antibodies, with Implications for Combined Therapy in Ovarian Cancer
Authors: Milagre Carla S. , Gopinathan Ganga , Everitt Gemma , Thompson Richard G. , Kulbe Hagen , Zhong Haihong , Hollingsworth Robert E. , Grose Richard , Bowtell David D.L. , Hochhauser Daniel , Balkwill Frances R.
Published: April 2023

Supplementary Figure 1. IL-6 inhibition activates EGFR
Supplemental Figure Legends from Adaptive Upregulation of EGFR Limits Attenuation of Tumor Growth by Neutralizing IL6 Antibodies, with Implications for Combined Therapy in Ovarian Cancer
Authors: Milagre Carla S. , Gopinathan Ganga , Everitt Gemma , Thompson Richard G. , Kulbe Hagen , Zhong Haihong , Hollingsworth Robert E. , Grose Richard , Bowtell David D.L. , Hochhauser Daniel , Balkwill Frances R.
Published: April 2023

Supplemental Figure Legends
Supplemental Table 1 from Accuracy of Molecular Data Generated with FFPE Biospecimens: Lessons from the Literature
Authors: Greytak Sarah R. , Engel Kelly B. , Bass B. Paige , Moore Helen M.
Published: April 2023

Table containing further information on papers included in review.
Supplementary Materials and Methods, Figure Legends from Genomic and Functional Analysis of the E3 Ligase PARK2 in Glioma
Authors: Lin De-Chen , Xu Liang , Chen Ye , Yan Haiyan , Hazawa Masaharu , Doan Ngan , Said Jonathan W. , Ding Ling-Wen , Liu Li-Zhen , Yang Henry , Yu Shizhu , Kahn Michael , Yin Dong , Koeffler H. Phillip
Published: April 2023

Supplementary Information includes Supplementary Materials and Methods, Supplementary Figure Legends and References. (FOR PUBLICATION)