bluuebunny/crossref_metadata_2025 huggingface dataset:
Foliar Application of Nano Fertilizer in Agricultural Crops: A Review
Authors: Acharya S.M. , Bhakare B.D. , Durgude A.G. , Thakare R.
Published: December 2023

To meet the food requirement of a huge population the food grain production need to be enhanced accordingly. However, the goal of higher production must not come at the cost of heavy exploitation of natural resources. In order to attain higher yields, need of the hour is to develop and promote new technologies and reform agricultural research. Nanotechnology helps to improve agricultural production by increasing the efficiency of inputs and minimizing relevant losses. Nano fertilizer is an important tool in agriculture to improve crop growth, yield and quality parameters with increased nutrient use efficiency, reduction in wastage of fertilizers and cost of cultivation Since the research work on nanotechnology in agriculture is at nascent stage there is a dearth of information on the response of nanomaterials application in crops. An effort has been made to review and extend the work done worldwide on foliar application of nano fertilizers in agricultural crops.
Successful Clinical Management and Molecular Investigation of Trypanosomosis in a Wild Captured Leopard
Authors: Kolangath S.M. , Pawshe M.D. , Dhoot V.M. , Upadhye S.V. , Kolangath R.M.
Published: December 2023

Background: Trypanosoma evansi is a widely prevalent trypanosomes of the Indian subcontinent and is widely documented in species like cattle, buffalo, horses, camel etc. In the wild, an array of animals like deers, jaguar, tigers, leopards, lions, foxes etc can be infected by the trypanosome. Trypanotolerance is an innate mechanism by which the wild animals harbour moderate infection without the development of clinical signs. Methods: The current report highlights the clinical management and molecular investigation of Trypanosomosis in a wild captured leopard. An adult male leopard, was found to exhibit partial inappetence with no other deviation from normal. Blood, serum and faecal investigations were carried out. A Polymerase Chain Reaction was carried out to gain molecular insights. The amplicon was purified and sequenced. The sequenced was submitted to NCBI after BLASTn analysis. Result: The blood smear revealed trypanosomosis while faecal examination revealed heavy infestation with Spirometra which was treated rationally. The animal showed an uneventful recovery after the treatment. The causative agent was identified to Trypanosoma evansi and was found to be identical to similar sequences reported from India and abroad by the phylogenetic analysis.
Environmental Research of Land Snail Diversity at Selected Rice Field in Lower Katingawan
Authors: Tadena Edgie
Published: December 2023

This study examined the variety and abundance of land snails in a specific rice field located in Lower Katingawan, Midsayap, Cotabato. Land snails are mollusks that dwell on land and possess spiral shells on their backs. Notably, no published research is available on land snails in the municipality of Midsayap, North Cotabato. The study identified three noteworthy species of land snails in the selected rice field, namely Paropeas achatinaceum, Achatina fulica, and Pomacea canaliculata, totaling 1048. The study utilized the quantitative-descriptive method and computed the diversity indices. Simpson's index was calculated, indicating a low probability of two randomly chosen individuals belonging to the same taxon. Shannon's index yielded a value indicating relatively low species richness and uneven distribution of individuals among taxa. These findings offer valuable insights into the community's structure and ecological significance, emphasizing the need for further research to comprehensively understand its diversity and dynamics.
Keywords: Biology; diversity indices; shells; snails; taxonomy; terrestrial ecosystem
Effectiveness of Gamma Ray Irradiation on the Quality of Cured Vanilla (Vanilla Planifolia A.)
Authors: Handayani Yossi , Budiastra I Wayan , Ahmad Usman
Published: December 2023

Vanili umumnya disimpan untuk tahap penuaan selama 2-6 bulan sehingga memicu pertumbuhan mikrob. Teknologi iradiasi dapat diterapkan untuk mereduksi mikrob pada vanili tujuan ekspor. Tujuan penelitian adalah menguji efektivitas iradiasi gamma terhadap mutu vanili hasil curing serta menentukan dosis iradiasi terbaik dengan mutu masih diterima oleh konsumen. Rancangan percobaan adalah rancangan acak lengkap faktorial dengan tiga ulangan. Faktor pertama dosis iradiasi sebanyak tiga taraf yaitu 10, 15 dan 30 kGy serta tanpa iradiasi (0 kGy) sebagai kontrol. Faktor kedua adalah bahan baku vanili hasil curing sebanyak tiga taraf yaitu vanili curing dengan pengering efek rumah kaca (ERK) tanpa peram lanjut, vanili curing dengan pengering ERK dan peram lanjut empat malam serta vanili curing hasil penjemuran petani. Pemberian iradiasi dilakukan pada vanili setelah penyimpanan selama dua bulan. Pengujian parameter mutu dilakukan sebelum dan sesudah iradiasi pada sampel yang dikemas, meliputi, fisik, kimia, mikrobiologi, dan uji organoleptik. Dosis iradiasi 10  kGy ditemukan efektif untuk mengurangi cemaran mikrobiologi  pada vanili tanpa peram dan dengan peram lanjut sesuai batas cemaran SNI, namun pada vanili penjemuran petani dibutuhkan dosis 15 kGy. Dosis iradiasi tidak memberi efek  terhadap susut bobot,  kadar air dan kadar vanilin sehingga mutu dan aroma masih baik. Iradiasi  meningkatkan nilai L* dan chroma namun kesukaan panelis  terhadap warna vanili masih bernilai 4 (agak suka)  hingga 30 kGy. Pemberian iradiasi meningkatkan kesukaan panelis terhadap aroma dari agak tidak suka (3) sebelum diiradiasi menjadi agak suka (4) setelah diiradiasi.
Studi Kritik terhadap Pandangan Tren Childfree menurut Pemahaman Hadis Analisis Sosiologi Keluarga
Authors: Rahmah Siti
Published: December 2023

The purpose of this study was to conduct a critical analysis of the free attitude of children based on the information provided by the hadith. This study uses a qualitative approach by applying the methodology of syarah and ma'anil hadith through descriptive analysis of family sociology with a comprehensive critical study. The results of the research and discussion show that there is an understanding of the hadith that criticizes the childfree view with an understanding of the hadith that recommends marrying a woman who produces many offspring. Even though at the time of the Prophet it was reported that there were companions who had the desire not to have children and did 'azl in practice, but that did not make 'azl more important to do, because 'azl is not useful because pregnancy may still occur. The conclusion of this study is that based on a sociological study of the family, the child-free phenomenon shows a shift in values related to children in society. This finding was obtained after the researchers conducted an analysis of the family, the loss of family function, the existence of gender equality, and was considered contrary to the construction of Indonesian society regarding the concept of the ideal family. This study recommends married couples not to choose childfree and consider having children in life after marriage because the Prophet will be proud of his many followers.
The Impact of Network Status Resources on Health: Moderation by Cultural
Authors: Rusinova Nina , Safronov Viacheslav
Published: December 2023

The article is devoted to such a problem as the impact of social relations on people’s health. One of the directions in researching this issue is linked to analyzing social capital — network resources available to an individual to solve everyday problems. The conceptual basis of the research is the theory of positional network capital by N. Lin, according to which being acquainted to persons with high professional status provides an individual with access to resources that are vital for one’s health and improves its condition. Previous studies conducted in certain countries in different parts of the world generally confirm this theoretical assumption, but it remains unclear why the impact of social capital varies across countries and whether this is due to contextual factors of their socio-economic development and cultural characteristics. To clarify these issues, survey data from the International Social Survey Program (ISSP) 2017 for 30 countries and information (statistical and aggregated) about the differences between them were used. The results of verifying the theoretical ideas about the dependence of state of health on the network resources available to an individual demonstrated that status resources really play an important role in contributing to preserving one’s health. It was also shown that the impact of status and social capital on health depends on the cultural context and is more clearly manifested when trust in other people is widespread in society.
Implozja „kawaii”. Serial „Paranoia Agent” Satoshiego Kona
Authors: Kamrowska Agnieszka
Published: December 2023

The article presents the anime TV series Paranoia Agent by Satoshi Kon and its major themes: escapism, lack of communication and the guise of victimhood, which is as a method of denial meant to mute a conscience burdened by the horrors of World War II prevalent in contemporary Japanese society. Certain phenomena of Japanese consumer culture, such as fine goods, kawaii and character goods are also presented. These phenomena form an important cultural background for an analysis of Kon’s oeuvre, as the author uses them as lens through which he portrays the problems facing contemporary Japanese society — not least of all the ways in which it is influenced by the ubiquity of media. His insights are quite well grounded in reality, and his conclusions are rather bleak. Even the apocalyptic destruction of Tokyo cannot change ways of the Japanese people, who are thoroughly engulfed by non-communication and hyper-consumerism.
Siła klątwy, magia wody i (nie)możność zmiany czasu w noweli „Jańcio Wodnik” Jana Jakuba Kolskiego
Authors: Rusek Iwona E.
Published: December 2023

The text raises the issue of the presence of the magical sphere in the human experience. Johnnie Waterman, the protagonist of a short story and a film by Jan Jakub Kolski, experiences a mysterious force that begins to govern his life. This secret power is related to water, through which the hero begins to heal, and in short order becomes a holy man of sorts. Using this character as and example, the author poses a question about the meaning of human fate and the moral aspects of human existence. He also shows human life as dependent on mythical and symbolic meanings that in fact create reality. Johnnie Waterman, who is finally undone by his own pride, wants to turn back time, because he believes that this magical “band-aid” will repair the harm he had caused. However, it is only his understanding of who he is and what he was doing that brings the desired change and makes the hero start living together with his family. The curse that befell Jańcio on the one hand unleashed evil, on the other — it became a chance for the hero to find the truth about himself and the surrounding world.
Sycylijskie obrazy — intertekstualne nawiązania w drugim sezonie serialu „Biały Lotos”
Authors: Snoch Marta
Published: December 2023

The article focuses on certain aspects of the cinematic and cultural references in the second season of HBO’s TV series The White Lotus. The author draws parallels between the classic works of Italian and Hollywood cinema and various themes of the series, its visual aspects and cast of characters. By comparing different approaches to characters and their arcs narratives the author describes various attempts to challenge the cultural clichés about Americans in Europe, but also stereotypes about Sicily and images of Italians in American cinema and television.
Z genealogii „niepokoju świata”. Ralf Konersmann o oświeceniu
Authors: Wrzeszcz Łukasz
Published: December 2023

Ralf Konersmann (ur. 1955) to dziś jeden z najbardziej cenionych fi lozofów kultury. Od ponad dekady — dzięki przekładom Krystyny Krzemieniowej — polski czytelnik zna dwie jego książki: Filozofię kultury. Wprowadzenie (2009) oraz Krytykę kultury (2012). Niezwykle interesujące są także późniejsze prace Konersmanna, diagnozujące współczesność jako stan nieustannego niepokoju (Unruhe), który przez lata się znormalizował. Mowa tu o książkach Die Unruhe der Welt (2015) oraz Wörterbuch der Unruhe (2017). Konersmann, stosując metodę genealogiczną, poszukuje historycznych źródeł tego stanu i przypisuje szczególną rolę oświeceniu. W artykule rekonstruuję Konersmannowską genealogię niepokoju świata opierając się przedstawionym w analizowanych książkach zarysie osiemnastowiecznej filozofii. Rozpoczynam od ogólnej koncepcji niepokoju, aby przejść do ukazania swoistej relacji niepokoju z nowoczesną krytyką oraz myślą mityczną. Z prac Konersmanna można bowiem wnioskować, że niepokój — jak i sama kultura — wyraża się przez krytykę, a oświeceniowe reinterpretacje mitu pozwoliły się z nim oswoić.
Factores asociados a las prácticas de identificación, diagnóstico y tratamiento de la comorbilidad tuberculosis-diabetes mellitus de médicos generales responsables de la Estrategia Sanitaria de Prevención y Control de Tuberculosis de una red de salud de L
Authors: Campos Coronel Hugo Rolando , Llanos Zavalaga Luis Fernando
Published: December 2023

Objetivo: Determinar los factores asociados a las prácticas de identificación, diagnóstico y tratamiento de lacomorbilidad tuberculosis-diabetes mellitus (TB-DM) de médicos generales responsables de la Estrategia Sanitaria de Prevención y Control de Tuberculosis (ES-PCT) de una red de salud de Lima. Material y métodos: Estudio cuantitativo observacional de tipo transversal analítico; realizado en centros de salud de la Red de Salud San Juan de Lurigancho (RS-SJL). Se aplicó un cuestionario que constó de dos partes: características sociodemográficas (6 preguntas) y prácticas de la asociación TB-DM (20 preguntas): identificación (2 preguntas), diagnóstico (7 preguntas) y tratamiento (11 preguntas). Se validó el contenido del instrumento por juicio de expertos, con 10 profesionales de la salud, entre metodólogos y temáticos; y para el estimado de homogeneidad se utilizó el coeficiente de Kuder-Richardson; en ambos casos se obtuvo significancia. Resultados: La población de estudio se caracterizó en el 61,8 % por ser de sexo masculino; el 50 % tiene entre 31 y 40 años de edad; y el 38,2 % ha trabajado en la ES-PCT entre 1 a 5 años. Entre las prácticas médicas, obtuvo mayor puntaje preguntar al paciente con TB sobre sus antecedentes familiares de DM, con el 94,1 %; seguido de registrar el dato en la parte de antecedentes de la historia clínica, con el 85,3 %. Solo el 20,6 % de los médicos presentaron prácticas adecuadas y se asoció con la edad (p = 0,01) y el tiempo en la ES-PCT (p < 0,05). Conclusiones: Los médicos generales responsables de la ES-PCT requieren mejorar las prácticas para el manejo de pacientes con la comorbilidad TB-DM.
An Initiative Report on Hospitalized Pulmonary TB Patients Co-Infected by SARS-CoV-2 during the COVID-19 Pandemic from Tertiary Referral Hospitals in Surabaya
Authors: Effendy Lyndia , Mertaniasih Ni Made , Soedarsono Soedarsono , Endraswari Pepy
Published: December 2023

The enduring effect of SARS-CoV-2 pandemic has been experienced throughout the past and ongoing three years. Incidences of SARS-CoV-2 co-infected tuberculosis patients were reported globally, including in Italy and several European countries and resulted in a more complicated disease with severe clinical features and poorer clinical outcomes. To effectively manage this co-infection, it is important to be informed of the prevalence and characteristics of an acute SARS-CoV-2 co-infection on TB and determining factors of severity. Therefore, early warning signs can be recognized, monitored closely and managed. This retrospective study, carried out on hospitalized TB patients in Dr. Soetomo Hospital and Universitas Airlangga Hospital, Surabaya, Indonesia, used medical records from March 2020 to December 2022. Samples were from inpatients with a molecularly-Gene Xpert MTB/Rif-confirmed tuberculosis, and currently experienced respiratory and fever symptoms that resembles the symptoms of SARS-CoV-2 infection or exacerbation of tuberculosis. They are then screened and examined using a molecular diagnostic test, with real-time RT-PCR for SARS-CoV-2. A total of 54 (0.7%) patients had TB-SARS-CoV-2 co-infection among 7,786 suspected to have TB, of which 35 had Rifampicin Sensitive (TB-RS), while 19 had TB Rifampicin Resistant (TB-RR) co-infected with SARS-CoV-2. The remaining 2,586 suspected TB patients had only MTB, based on the detection methods of X-pert MTB/RIF, but with negative RT-PCR of SARS-CoV-2. The clinical severity and mortality of TB-SARS-CoV2 co-infected patients were significantly associated with the number of co-morbidities (p=0.0156), and serum haemoglobin levels (p=0.0672), in which p value < 0.05 is considered significant.
Polyvinyl Chloride (PVC)-Glycerol with Chitosan Addition for Antibacterial Blood Bag Application
Authors: Widiyanti Prihartini , Tarissa Diandra Putri Wibowo  , Baskoro Andhi , Siswanto
Published: December 2023

Blood bag is a medical device that stokes and transports whole blood or blood components. The material that is often used for blood bag membranes is Polyvinyl Chloride (PVC), however the common problem that is bacterial contamination and that material have not antibacterial characteristic.  Because of this matter, the aim of this reseach are a blood bag that has antibacterial function is needed and meet the ideal standard as bloodbag. Chitosan as a blood bag membrane material fabrication to get the antibacterial effect. Chitosan is chosen as a blood bag material fabrication to get the antibacterial effect. Chitosan has several specific biocompatibility properties, antibacterial, chelation, and biodegradability. This study used various Chitosan concentrations of 1.5%, 2%, 2.5%, and 3%, and Glycerol was added as a plasticizer. The composition of Chitosan: Glycerol is 1:1. Then, the mixture is added to the PVC solution in a ratio of 1:5 then poured into a petri dish. The results showed characterization that the biocomposite PVC-Glycerol with the addition of 3% concentration of chitosan was the best composition, the tensile strength test result of biocomposite is 21.20 MPa, the absence of membrane pores in the morphology of the blood bag, the hemolytic activity is 0.24%, and the inhibition zones of E. coli and S. aureus, respectively 11.66 mm and 12.66 mm in diameter. Based on the characterization results, the biocomposite PVC-Glycerol membrane with the addition of Chitosan has a very high potential as a candidate for blood bag membranes
A Peculiar Manifestation of Urinary Tract Infection in a 76-year-old Female
Authors: Alius Cahyadi  , Angelina Yuwono  , Nicholas Adrianto  , Patricia Michelle Lukito
Published: December 2023

Purple Urine Bag Syndrome (PUBS) is a rare and benign clinical phenomenon associated with urinary tract infections, characterized by the distinctive purple discoloration of a urinary catheter bag. The underlying cause of PUBS is related to bacterial activity involved in the breakdown of tryptophan, mainly in individuals with predisposing factors such as long-term catheterization, constipation, alkaline urine, and being female. We present the case of a 76-year-old female patient with a history of tuberculous spondylitis who developed PUBS during her hospital stay. The patient had been bedridden for three years and had been given a urinary catheter, which was routinely replaced by a non-medical family member and without a proper antiseptic procedure. A urine culture revealed the presence of Proteus mirabilis, and the patient was treated with intravenous antibiotics while also replacing the urinary catheter and bag. After five days of treatment, the urine bag and catheter remained clear, and the patient was discharged. PUBS is a significant indicator of urinary tract infection, necessitating prompt medical intervention to prevent complications. Healthcare professionals should be aware of this syndrome to enable early detection and appropriate management.
Screening of Legionella pneumophila from Well Water in Magetan Regency, Indonesia
Authors: Hapsari Nafisah Nurul , Kurniawan Muhammad Ridho Hafid , Sucipto Teguh Hari , Fajar Nur Syamsiatul , Herupradopo Eduardus Bimo Aksono , Fauziyah Shifa , Widya Alicia Margaretta , Aquaresta Febriana , Sin War Naw
Published: December 2023

Legionellosis is a respiratory infection caused by Legionella pneumophila, a bacterium that can infect protozoa and human lung cells. The disease can be mild or severe, and sometimes fatal, especially in immunocompromised people. Some types of antibiotics that can be used to treat Legionella disease are macrolides such as rifampicin, azithromycin and clarithromycin, as well as fluoroquinolones such as levofloxacin and moxifloxacin. The aim was to investigate the distribution and prevalence of Legionella in well water. This study collected and tested water samples from a different well water in Magetan Regency, East Java, Indonesia using DNA extraction, two-step PCR methods, and visualization with 1.5% agarose gel in UV transluminator. The results were visualized with QGIS 3.28.6 and compared with other tests. The results showed that none of the eight water samples were contaminated with L. pneumophila compared with positive control (403 bp).
Tempo de exposição à radiação nas osteossínteses com hastes intramedulares nos membros inferiores
Authors: Alencar Neto Jonatas Brito de , Helito Camilo Partezani , Vasconcelos Jônatas Ponte , Félix Diego Freitas , Pinto Neto Luiz Holanda , Lima Diego Ariel de
Published: December 2023

Objetivo: Avaliar o tempo de fluoroscopia intraoperatória em osteossínteses com haste intramedular das fraturas diafisárias do fêmur e/ou tíbia. Métodos: Estudo observacional, descritivo e retrospectivo, através de estudo dos prontuários de pacientes admitidos com fraturas na região diafisária da tíbia e/ou do fêmur e submetidos a tratamento cirúrgico com haste intramedular. Resultados: O tempo médio de fluoroscopia por procedimento foi de 239 ± 157 segundos. A comparação do tempo de fluoroscopia entre tipos de cirurgia indicou a haste retrógrada de fêmur como menor necessidade de imagens fluoroscópicas (p<0,001). Quando o procedimento foi realizado pelo staff o tempo de cirurgia foi mais reduzido (195 ± 43,3 minutos para os residentes e 154 ± 10,8 minutos para os Staffs, p= 0,018). O tempo médio de fluoroscopia por procedimento não houve diferença significativa (p=0,508) em relação a quem fez a cirurgia (Staff ou residente). Conclusão: A fixação com haste retrógrada de fêmur exigiu menos tempo de fluoroscopia em comparação com a haste femoral cefalomedular longa e haste de tíbia. Quando os cirurgiões ortopédicos realizavam a cirurgia obtiveram menor tempo de cirurgia em comparação com os médicos residentes.
Autonomous method for a strapdown inertial navigation system calibration in operation in operation
Authors: Uspenskyi Valerii
Published: December 2023

Strapdown inertial navigation systems (SINS) are widely used in modern air transport. The service life of such systems is decades. During this time, the characteristics of such systems may deteriorate due to the degradation of inertial sensors - gyroscopes and accelerometers. Under these conditions, in order to maintain the required accuracy of the SINS during the entire period of operation, it is necessary either to periodically carry out routine maintenance with the onboard system, or to continuously adapt the used sensor measurement model in terms of compensating for errors that arise. The second direction, which we will call calibration, has the advantage over the first one that it is carried out automatically by the system itself and does not require any additional equipment or additional maintenance work. The known method of SINS recalibration is based on the integration of information from the SINS and from the receiver of satellite radio navigation signals (SRNS). Such calibration, firstly, significantly depends on the availability and quality of satellite information, and secondly, it is possible only for integrated navigation systems in which the inertial subsystem is supplemented by a SRNS receiver. In contrast to the known method, this article solves the problem of autonomous SINS calibration, which is carried out after each flight. The solution is based on a linearized inertial navigation error model based on the boundary conditions of the state vector (at the beginning and end of the flight). The external information used consists only of the initial values of the coordinates and the current measurements of the baroaltimeter. As a result of the decision at the end of the flight, the errors of gyroscopes and accelerometers are determined, as well as the error in determining the final values of latitude and longitude in the SINS. Sensor errors can be used in subsequent system activations, which improves the accuracy of its operation as a whole. The analysis of the suitability and effectiveness of the developed methodology was carried out on a typical flight simulation program.
Minimization of the weight of the blade of the aerial installation by an adaptive hybrid optimization method
Authors: Lapitan Konstantin , Misura Serhii , Listrova Daria , Rudenko Tetiana , Misura Ievgeniia , Vasiliev Anatolii
Published: December 2023

In various fields of engineering practice, such as turbine building, power engineering, elements of thin-walled structures are widely used, which operate under increased loads when interacting with air or water. These include blades of impellers of radial-axial and rotary-blade hydraulic turbines, blades of wind power plants. Designing highly efficient machines and structures with the required level of reliability requires determining their optimal characteristics. The article proposes an adaptive method for finding the minimum of an arbitrary smooth multivariable function. The method was used to solve the benchmark optimization problem of a function in the form of a valley. The essence of the proposed algorithm lies in the sequential approach to the bottom of the valley and the subsequent movement in the direction of decreasing the objective function. Comparison of the results of calculating the minimum point of the function is performed using both non-gradient and gradient methods, namely: Powell, Hook-Jeeves, the steepest descent method and the developed method. It was found that the effectiveness of the proposed method is greater than the usual search algorithms, but it is not without its drawbacks. The method is proposed that represents a number of hybrid methods, which form a hybrid coalition Proposed hybrid algorithm does not provide a satisfactory result in the "single" search. The search algorithm reaches a point where all the values of the function at the surrounding points are greater than the values at the obtained point, and the algorithm cannot overcome the barrier. To solve the problem, it is necessary to take the obtained point as a new starting point and repeat the algorithm for finding the minimum of the function, that is, use the multistart method. The proposed method was used to solve the problem of optimizing the blade of an air installation, which was reduced to the problem of unconditional optimization using the method of penalty functions, but the goal function had a significantly valley structure. The optimal values of section thicknesses were obtained, which made it possible to build a blade with improved characteristics.
Development of a mobile application for checking the level of English knowledge using the SWIFT programming language and the UIKIT framework
Authors: Krasulia Daria , Ivanchenko Kseniia , Ivanchenko Dmytro
Published: December 2023

This scientific work is aimed at the development and implementation of an innovative mobile application aimed at assessing the level of knowledge of foreign languages. The main goal of the study was to create a convenient and fast tool that allows users not only to determine their level of language competence, but also to identify shortcomings and determine the optimal path for further improvement.

In the course of the study, the existing methods and systems for evaluating language skills were carefully analyzed. Based on this analysis, detailed functional and non-functional requirements for the developed software product were formulated. The choice of technical and software tools, in particular the Swift programming language and the IOS operating system, was justified by their relevance and the ability to create applications for all devices in the Apple ecosystem.

A significant part of the work was the creation of a database using the non-relational Realm system for mobile devices. The application interacts with data in JSON format, which allows you to efficiently load and display lists of questions for users. In the development process, such libraries as Foundation, UIKit, RealmSwift and others were used in order to ensure optimal performance and reliability of the application.

Special attention was paid to creating an intuitive and convenient interface for users. The development process included a careful design of the logic and structure of the mobile application in order to ensure maximum convenience during use.

One of the key parts of the research was testing the developed application. UI testing was carried out to check the correctness and usability of the interface, compatibility testing to ensure operation on different devices, and functional testing to check compliance with all defined requirements.

As a result of the research, an information system for automated testing that meets high standards and requirements was successfully developed. The obtained results can serve as a basis for the integration of the program into the educational process or to provide students with the opportunity to gain practical skills in assessing their language competence.
DIAGNOSTICS OF THE LOGISTICS FLOWS MONITORING SYSTEM
Authors: Volosnikova Nataliia
Published: December 2023

The article delves into an in-depth examination of methods and tools designed to facilitate the efficient analysis and control of goods movement within contemporary logistics systems. It places a particular emphasis on critical diagnostic aspects, including the determination of efficiency, identification of potential issues, and the optimization of monitoring processes. The study focuses on exploring diagnostic methods tailored to assess efficiency levels and identify deviations that may occur in the course of goods flow.

A comprehensive analysis is conducted on the utilization of innovative technologies and advanced analytical tools to elevate the precision and operational efficiency of logistics system diagnostics. The article explores the intricate dynamics of the interaction among different components of the monitoring system, shedding light on their collective impact on the efficiency of logistics processes. Moreover, potential strategies for optimizing interaction and communication within expansive logistics networks are considered, aiming to achieve the pinnacle of productivity.

Beyond this, the article extends its inquiry to the interplay among various elements within the monitoring system, probing into their influence on the holistic efficiency of logistics processes. The exploration encompasses a discussion of viable pathways for optimizing this interaction, ultimately striving for the attainment of not only the highest productivity but also the most judicious utilization of resources.

The insights derived from the article are poised to offer significant utility to logistics professionals seeking to enhance the monitoring systems governing logistic flows. Researchers with an interest in advancing logistics monitoring systems will find valuable perspectives, and practitioners eager to integrate cutting-edge technologies into their logistics management strategies stand to gain practical guidance from the article's findings.
DEVELOPMENT OF METHODS FOR EFFECTIVE SELECTION OF EQUIPMENT FOR TOURISM AND HOTEL AND RESTAURANT BUSINESS
Authors: Yakymenko-Tereshchenko Nataliia , Aleksandrova Viktoriia , Strygul Larysa
Published: December 2023

Tourism and hotel restaurant business is a promising area of entrepreneurship development in Ukraine. One of the main tasks of its successful management remains the rational selection of equipment and energy-efficient technologies, which allow entrepreneurs to open up new opportunities for attracting customers, which can subsequently cause a new push for the development of this business in Ukraine. The relevance of the topic of the article is due to the fact that the hotel and restaurant business is one of the branches of the food industry, in which the requirements for the quality of services and products are extremely high. This determines the high quality of the necessary equipment, which in turn leads to an increased financial burden on this business. The modern equipment market offers consumers a wide range of restaurant equipment of different price categories and quality. When choosing equipment for the hotel and restaurant business, it is necessary to take into account the quality and guarantees offered by the manufacturer; price, country of manufacture. To effectively solve this problem, the business owner needs to attract highly qualified specialists from this field, which entails additional costs, or try to solve this problem on his own. The purpose of the article is the formation of generalized recommendations on the use of equipment selection methods for the hotel and restaurant business based on the criterion of energy efficiency and competitiveness. The article reviews the problem of choosing the necessary equipment for the hotel and restaurant business, considers the main types of equipment used and its technological indicators, and defines the main economic indicators that should be taken into account for its effective selection.
Strong Association Between Growth Hormone Therapy and Proximal Tibial Physeal Avulsion Fractures in Children and Adolescents
Authors: Beber Samuel A. , Gross Preston W. , Nichols Erikson , Green Daniel W. , Fabricant Peter D.
Published: December 2023

Background:

Published literature describes slipped capital femoral epiphysis as a complication of recombinant human growth hormone (rhGH) therapy that may be related to decreased physeal strength. The purpose of the current investigation was to utilize a case-control study design to determine whether a greater proportion of pediatric patients sustaining physeal avulsion fractures of the proximal tibia were undergoing rhGH therapy at the time of injury compared with a cohort of matched controls.

Methods:

A case-control design study design was utilized. Patients 4 to 18 years of age with proximal tibial physeal avulsion fractures (cases) or midshaft tibial fractures (controls) at our institution from February 1, 2016, to May 4, 2023, were identified. Cases and controls were matched 1:1 on the basis of age (within 1 year), sex, and body mass index (within 3 kg/m2). A total of 132 patients were included in the analysis (mean age, 13 ± 2 years). rhGH exposure was compared using conditional logistic regression with Firth correction.

Results:

We found that 11% of the patients with a proximal tibial physeal avulsion fracture were on rhGH therapy at the time of injury compared with 0% of patients with midshaft tibial fractures (odds ratio [OR], 15.0; 95% confidence interval [CI], 1.8 to 1,946.7; p = 0.007). There was no significant difference in the proportion of sports-related injuries between cases (70%) and controls (67%) (OR, 1.15; 95% CI, 0.55 to 2.39; p = 0.85). Among subjects with proximal tibial avulsion fractures, the proportion requiring surgery did not differ significantly between patients receiving and those not receiving rhGH therapy (43% versus 41%, respectively; p = 0.99).

Conclusions:

This study demonstrates that the proportion of subjects who sustained proximal tibial physeal avulsion fractures and were receiving recombinant human growth hormone therapy at the time of injury was significantly greater than that of an age, sex, and body mass index-matched control group with midshaft tibial fractures (11% versus 0%, respectively, representing 15-times greater odds of exposure). This quantifies a previously unreported serious orthopaedic complication associated with rhGH therapy.

Level of Evidence:

Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
Differentiation of Lamproitic Magma: Case Study of Mesozoic High-K Dikes of the Ryabinovyi Massif (Central Aldan)
Authors: Izokh A.E. , Chayka I.F. , Gaskov I.V. , Egorova V.V.
Published: December 2023

––Studies of the mineral–petrographic and geochemical compositions of high-potassic lamprophyric dikes of the Tobuk complex, manifested at the Ryabinovyi plutonic massif (Central Aldan Mesozoic magmatic province, Russia), have shown that these dikes compose a single fractionation series formed from a high-Mg lamproitic parental melt in an intermediate chamber. The composition of the rocks ranges from olivine–diopside–phlogopite and diopside–phlogopite lamproites through minettes to microsyenites and syenite–porphyry. Early crystallization of high-Mg olivine and chromite in an intermediate chamber could produce cumulative dunites similar to those of the Inagli intrusion. Crystallization of olivine and chromite was followed by cotectic crystallization of olivine and clinopyroxene, then that of clinopyroxene and phlogopite, and, finally, eutectic crystallization of Na-rich clinopyroxene, phlogopite, and K-feldspar. Crystallization and gravitational differentiation of lamproitic melt was complicated by silicate–carbonate immiscibility, which is texturally manifested in minettes as carbonate–silicate globules and interstitial calcium and magnesium carbonates. Furthermore, compositional zoning of Sr in apatite and Ba in phlogopite and K-feldspar is considered to have resulted from the immiscibility. Separation of the carbonate–fluorite melt fraction might have led to formation of the carbonatite and fluorite–carbonatite schlieren and gangues which have been described in drill cores from the Ryabinovyi massif. In most of the geochemical and mineralogic features, the Ryabinovyi massif lamproites are similar to the low-Ti lamproites of the Mediterranean postcollisional belt and northern Vietnam and differ from typical high-Ti within-plate lamproites.
Detrital Chrome Spinels of the Udokan Sedimentary Basin in Transbaikalia
Authors: Novoselov K.A. , Belogub E.V. , Blinov I.A. , Artem’ev D.A.
Published: December 2023

––The Udokan sedimentary basin is a unique geological structure containing many copperstone deposits and occurrences. A detrital chrome spinel is identified in the metasandstones of the Sakukan Formation at the Udokan and Unkur deposits, which tend to interlayers of natural heavy mineral concentrates. The mineral forms relict inclusions in magnetite crystals. Its composition is distinguished by high concentrations of zinc (up to 11.62 wt.% ZnO) and manganese (up to 6.32 wt.% MnO) with an almost complete absence of magnesium. In comparison with the associated magnetite, chromite is significantly enriched in germanium (up to 666 ppm) and gallium (up to 59.1 ppm). The formation of Zn-chrome spinel occurred during the transformation of detrital chromite against the background of specific chemical processes accompanying the deposition and crystallization of iron gel enriched with adsorbed impurities.
Fermented and Distilled Beverages Tej and Areki (an ethnic, indegenous food of Ethiopia)
Authors: Yalew Temesgen Awoke , Zeru Tesfaye , Assefa Teshome , Tesfaye Biniyam , G/Giorgies Taddesse , Bitew Abebe , Taddesse Chere , Tesfaye Kelemua , Demelash Yoseph , Yehualashet Asrat , Tefera Nahom , Ashenafi Negat , W/Yohannes Messeret , Legesse Addisu , Gobene Waqtole , Abera Andinet , Wodajo Birhanu , Andualem Misganaw , Tessema Masresha
Published: December 2023

Alcoholic beverages are a part of the human dietary culture. In Africa, fermented alcoholic beverages are consumed on different occasions. Beverage production depends on the type of food, fermentation process duration, and application of microbes utilized for fermentation. Ethiopia is one of the countries where many traditional fermented beverages are prepared and consumed. Tej, Areki, Tella, kribo, borde, and korfe are the most common. However, information regarding this indigenous product is limited. Most of the recipes and the preparation methods are not documented and studied. This study was undertaken to collect indigenous knowledge, practices, mode of preparation, and skills, as well as to generate data on the functional properties and chemical composition of Tej and Araki. The study includes information on ingredients, pH, electrical conductivity, specific gravity, methanol and ethanol content, total acidity, esters content, and acetaldehyde content. Previous research supports the findings, indicating consistency in the characteristics of Tej and Areki across studies.
Acoustic Energy Harvesting From Sonic Crystals with Non-square Lattices Using Piezoelectric Patch
Authors: Sharifi-Moghaddam Saeed , Ziaei-Rad Saeed , Hafshjani Reihaneh Hadipour , Tikani Reza
Published: December 2023

Energy harvesting from the environment has been one of the important challenges for researchers in recent years. Acoustic energy is one of the natural sources of mechanical energy that can be converted into electrical energy by using metamaterial or piezoelectric. In such a way that by creating a defect in a regular lattice of the crystal, at the point of defect, the concentration of sound pressure was created, and by installing the PVDF piezoelectric patch, mechanical energy can be converted into electrical energy. In this research, to identify a suitable model to harvest maximum acoustic energy, the effect of various lattices including circular, rhombus, rectangular, square-rhombic, square-rectangular, and rhombus-rectangular lattices on the sound pressure level (SPL) and energy harvesting was investigated. Also, the effect of changing the position of the defect and increasing the number of defects on the SPL was studied. The simulated results were calculated using Comsol Multiphysics 6.0. The validation of the results was confirmed by comparing them with the results of previous studies. The results showed that a square-rhombic lattice can provide the highest SPL and consequently the highest harvested energy. In the square-rhombic lattice, by using the optimal resistance of 15 kΩ at the frequency of 4220.4 Hz, the voltage and power were 11.34 mV and 4.15 nW, respectively.
Influence paths and transboundary impacts of green finance on sustainable development goals across China: a mediating effect and spatial econometric analysis
Authors: Li Chenggang , Bao Youhui , Jiao Xinying , Yue Mu , Shang Guofei , Wu Liang
Published: December 2023

Sustainable development is a global consensus, and green finance is considered to have important impact on the sustainable development. However, there is limited research exploring the influence paths and transboundary impacts of green finance on the sustainable development. In this study, we developed an assessment system for green finance (GF) and sustainable development goals (SDGs) and used China’s provincial panel data over the period 2008–2020. We utilized the panel data model, mediating effect model, and spatial Durbin model to examine the effect, influence paths, and transboundary impacts of green finance on the SDGs. Our findings reveal that GF has a significantly positive influence on the SDGs. GF promotes the SDGs by adjusting the industrial structure, promoting green innovation, and reducing energy consumption and CO2 emissions. Notably, the positive effect of GF on the SDGs has prominent differences in eastern, central and western China, and the establishment of a green finance system significantly strengthens the effect. Furthermore, we found that the synergistic effect of GF in peripheral provinces contribute to SDGs progress of local provinces, especially in eastern region and the period over 2016–2020. This study provides valuable insights for the world to develop green finance and achieve sustainable development.
Setting the environmental performance threshold for diverting residual streams towards bioeconomy strategies
Authors: Javourez U. , Karan S.K. , Hamelin L.
Published: December 2023

To shift towards low fossil carbon economies, making more out of residual biomass is increasingly promoted. Yet, it remains unclear if implementing advanced technologies to reuse these streams really achieves net environmental benefits compared to current management practices. By integrating resource assessment methods, consequential life cycle analysis (LCA) and uncertainty analysis, we propose a single framework to quantify the residual biomass baseline, which is the environmental threshold any bioeconomy strategy should overpass. For France, we estimate the residual biomass baseline to generate 18.4 ± 2.7 MtCO2-eq.y-1, 255 ± 35 ktN-eq.y-1 and 12,300 ± 800 diseases per year (particulate matter formation). More than 90% of total environmental impacts and associated uncertainties were found attributable to the conventional management of crop residues and livestock effluents. We systematically assessed the environmental impacts associated with each residual stream, by reporting potential improvement measures and actions to reduce uncertainties. Overall, reusing residual streams as fertilizing products is currently supplying more than half of total P and K demand for France, but only 6% of the nitrogen demand, due to volatilization and prevailing farming accounting practices. Moreover, only 3% of residual streams are currently diverted to energy recovery. We argue that current situation is not a suitable reference for bioeconomy trajectories, as efforts to improve the agricultural and energy reuse of residual streams are already underway. These include the wide deployment of anaerobic digestion and the prioritization of biogas to suply sectors without decarbonization options, among others. We suggest any alternative bioeconomy strategy should rather compare to this projected baseline, estimated for France at 8.5 MtCO2-eq.y-1. The proposed framework is a stepping stone in defining indicators tailored to track the environmental relevance of bioeconomy strategies, but should be integrated with spatially-explicit LCA to guide local waste management planning.
Structural mechanisms of potent lysophosphatidic acid receptor 1 activation by nonlipid basic agonists
Authors: Nureki Osamu , Akasaka  Hiroaki , Sano Fumiya , Shihoya Wataru
Published: December 2023

Lysophosphatidic acid receptor 1 (LPA1) is one of the G protein-coupled receptors activated by the lipid mediator, lysophosphatidic acid (LPA). LPA1 is associated with a variety of diseases, and LPA1 agonists have potential therapeutic value for treating obesity and depression. Although potent nonlipid LPA1 agonists have recently been identified, the mechanisms of nonlipid molecule-mediated LPA1 activation remain unclear. Here, we report a cryo-electron microscopy structure of the human LPA1-Gi complex bound to a nonlipid basic agonist, CpY, which has 30-fold higher agonistic activity as compared with LPA. Structural comparisons of LPA1 with other lipid GPCRs revealed that the negative charge in the characteristic binding pocket of LPA1 allows the selective acceptance of CpY, which lacks a polar head. In addition, our structure showed that the ethyl group of CpY directly pushes W271 to fix the active conformation. Endogenous LPA lacks these chemical features, which thus represent the crucial elements of nonlipid agonists that potently activate LPA1. This study provides detailed mechanistic insights into the ligand recognition and activation of LPA1 by nonlipid agonists, expanding the scope for drug development targeting the LPA receptors.