bluuebunny/crossref_metadata_2025 huggingface dataset:
Prevalence Of Low Back Pain and Disability Among Computer Operators Working in The Banks of Peshawar
Authors: Rehman Muheeur , Ullah Kashif , Wajid Abdul , Zeb Taimur , Ahmad Uzair , Rehman Faiz ur , Tahir Ahmad
Published: October 2022

Low-back disorders are linked to awkward postures and hinders both work performance and quality of life. Objective: The aim of this study was to find the prevalence of low back pain and disability among computer operator working in banks of Peshawar. Methods: A cross sectional study was conducted on 300 computer operators. The UBL, HBL and BOK Banks in Peshawar were targeted for recruitment of participants. Non probability convenience sampling technique was used for subject’s enrolment. Both male and female participants with age ranges from 25 to 50yr, working as computer operator in banks were included in study. The Oswestory of low back pain questionnaire and Numeric pain rating scale questionnaire were used to collect the data from the participants. Results: Out of 300 participants, maximum age respondents were 185 (61.7%) range from 25-33 years and minimum age were 26 (8.7%) ranged in 43-50 years. Male enrolled responses were 273 (91.0%) while females were 27 (9.0%). The prevalence of low back pain was 72.3 % among computer operators working in the banks of Peshawar. Based of NPRS, 27.7% computer operator reported no pain while the maximum number of participants i, e., 39.3% (n=118) suffered from mild pain. The maximum participants have minimal disability and reported as 52% (n= 156) while the minimum participants, only 10% (n=30) have sever disability. Conclusions: The current study revealed that, the prevalence of low back pain is high among computer operators working in Peshawar banks.
Prevalence and antibiotic susceptibility of clinical staphylococcus aureus isolates in various specimens collected from a tertiary care hospital, Hayatabad, Peshawar, Pakistan.
Authors: Rehman Latif Ur , Afzal Khan Amir , Afridi Pashmina , Ur Rehman Sadeeq , Wajahat Muhammad , Khan Furqan
Published: October 2022

Staphylococcus aureus is a notorious Gram-positive, non-spore-forming, opportunistic bacterium that causes a variety of infections including bacteremia, endocarditis, pneumonia, skin and soft tissue infections, and several others. Also, the overuse and misuse of drugs attributed to the crises of multidrug resistance especially in MRSA. Objective: Therefore, the aim of this study was to determine the prevalence rate of MRSA, antimicrobial susceptibility profiles of S. aureus, MRSA, and MSSA isolates to a variety of commonly used antibiotics, and its multidrug resistant patterns. Methods: Samples were collected from the microbiology department of HMC Peshawar, Pakistan. Antibiotic susceptibility patterns were determined under CLSI and EUCAST guideline, 2021 by following the Kirby-Bauer disc diffusion method. Results: Out of 106 S. aureus clinical isolates, 83 (78.3%) isolates were identified as MRSA and 23 (21.7%) were MSSA. In MRSA high resistance was exhibited to Penicillin G and cefoxitin (100%), followed by erythromycin 84.34% and ciprofloxacin 79.52%. Meanwhile low resistance was observed to doxycycline 19.28% followed by chloramphenicol 14.46%, teicoplanin and linezolid 2.41% for each respectively. High sensitivity in MRSA isolates was exhibited to linezolid 97.59% followed by teicoplanin 95.18%, chloramphenicol 85.54%, doxycycline 80.72% and fusidic acid 74.70%. A total of n=94 (88.67%) isolates were characterized as MDR. Conclusions: In conclusion, the most effective antibiotics used to treat S. aureus infections were linezolid, teicoplanin, chloramphenicol, doxycycline, fusidic acid, and gentamycin. In addition, the current study also noticed a significant prevalence of resistance to several antibiotics, emphasizing the importance of antibiotic usage monitoring.
Comparison of Sustained Natural Apophyseal Glide and Natural Apophyseal Glide Effects on Pain, Range of Motion and Neck Disability in Patients with Chronic Neck Pain
Authors: Saleem Iqra , Ahmed Zahoor Idrees , Ali Rana Arif , Sarfraz Shaina , Ibrahim Mubshra , Ghaffar Noman
Published: October 2022

Neck pain is very common in this era, and people have been suffering for many years. As the more advanced techniques of Mulligan, Sustained Natural Apophyseal Glide and Natural Apophyseal Glide are used to relieve pain, increase range of motion, and reduce neck disability in patients with chronic neck pain. Objectives: To compare the efficacy of sustained natural apophyseal glides and natural apophyseal glides in patients of with chronic neck pain. Methods: In this study, randomized clinical trial was done, a total of 45 subjects met the inclusion criteria out of which 5 were dropped out. 40 participants were included, both male and females diagnosed with chronic neck pain between the age of 25-50 years, and 20, 20 patients were randomly allocated into group A and B. Outcome measure tools were visual analog scale and Neck Disability Index (NDI) to assess. Group A received sustained natural apophyseal glides, Group B received natural apophyseal glides three times per week for 2 weeks. Results: In this study, the intragroup analysis revealed that relief of pain, improvement in range of motion, and reduction in disability were statistically significant in groups A and B (p<0.5). While Group A was statistically significant as compared to Group B. Conclusions: This study concluded that both the groups are effective, but the Sustained Natural Apophyseal Glides technique was more effective in pain relief, improvement of cervical range of motion, and reduction of neck disability in patients with chronic neck pain
Outcome Comparison of Stapled Versus Hand-Sewn Anastomosis in Elective Gastrointestinal Surgeries
Authors: Tariq Ghafoor Muhammad , Sabir Sohail , Tumrani Rukhsana , Kauser Noreen , Haider S. Sabahat
Published: October 2022

Bowel loop anastomosis is considered as major part of elective gastrointestinal surgeries. The anastomotic procedures being used now a days include hand sewn and stapled anastomosis. For appropriate gastrointestinal anastomosis, many factors should be considered such as intraoperative duration, restoration of blood supply, restoration of normal function of gastrointestinal tract and decrease tissue damage. Objective: The objective of the study was to compare the outcome of stapler and hand sewn anastomosis in elective gastrointestinal surgeries. Methods: Cross-sectional observational study conducted in department of surgery, Sheikh Zayed Hospital, Rahim Yar Khan from May 1, 2021 to August 31, 2022. Total 60 patients included in study and outcome variables such as anastomotic integrity, duration of procedure, post-operative hospital stay and return of bowel activity compared in hand sewn and stapled anastomosis. Results: The study included total 60 patients out of which 38 (63.33%) underwent stapled anastomosis and 22 (36.66%) underwent hand sewn anastomosis. Age (P value: 0.373), gender (p value: 0.372), anastomotic site (p value: 0.284) and return of bowel activity (p value: 0.331) did not show statistically significant difference between two groups. Anastomotic integrity (p value: 0.025), duration of procedure (p value: 0.002), post-operative hospital stay (p value: 0.037) show statistically significant difference between hand sewn and stapled anastomosis. Conclusions: Stapled anastomosis has better anastomotic integrity, reduced duration of procedure and decreased post-operative hospital stay as compared to hand sewn anastomosis with statistically significant difference between two groups.
Perception of nursing students towards educational quality in Khyber Pukhtankhwa Pakistan
Authors: Sohni . , Khan Sheraz , Ahmed Fayaz , Shabana . , Khan Ismail , Sultan Amir
Published: October 2022

Quality education is among the 17 Sustainable development goals recognized by the United Nations in September 2015. Quality education means that "Quality learners, a quality learning environment, quality materials, quality processes, and quality outcomes emphasize the necessity of focusing on all five key characteristics that are all vital aspects of education given by an education system". Objective: To assess the perception of nursing students towards educational quality in Khyber Pakhtunkhwa. Methods: A descriptive cross-sectional study was conducted in the nursing institutes of Khyber Pakhtunkhwa through a self-structured questionnaire from May 2022 to July 2022 having a sample size of 236. Results: The overall positive views of the students were (77%) towards the educational quality. The maximum mean score of students towards education quality was agree (45±9), then strongly agree (21±7), followed by neutral (14±3), strongly disagree (11±7), and disagree (9±6). Conclusions: There was a positive perception of students towards educational quality, but there are some factors that required paying attention.
A Prospective Study On the Surgical Treatment of Large Hypertensive Basal Ganglia Bleed
Authors: Munwar Ali Muhammad , Muzaffer uddin Muhammad , Shibli Zaheen , Kumar Ramesh , Muhammad Zeeshan Qazi , Zulfiqar Farrukh
Published: October 2022

Spontaneous intracerebral bleed is a communal subtype of stroke and is usually the deadliest. Objective: To determine the efficacy of surgical management of spontaneous hypertensive basal ganglia bleed and the factors contributing its outcome. Methods: A prospective study was carried out in the department of Neurosurgery for two-year duration from January 2020 to December 2021. 80 patients aged 18-65 years were included after matching criteria of inclusion of this study. The open craniotomy and evacuation was the surgical technique in all patients. After treatment, all cases were followed up for minimum six months. Patients were categorized as having good or bad scores on GOS. The data analysis was done using SPSS by assessing the effect of the observed variables including age, GCS, volume of blood, midline shift, ventricular extension and hydrocephalus. Results: 80 patients, 55 (68.8%) males and 25 (31.2%) females were done with surgical intervention. Their ages ranged from 18-65 years. Conferring to the patients GCS, they were divided into 3 groups: 26 (32.5%) patients with 5-8GCS; 38 (47.5%) patients with 9-12 GCS; and 16 (20%) patients with 13-15GCS. The volume of blood ranged from 30-90 cm3. 13 patients (16.3%) had ventricular extension, and 9 patients had hydrocephalus. In 34 patients (42.5%) had midline shift was <5 mm and 46 patients (57.5%) had > 5 mm. 49 patients (61.3%) had favorable results conferring to GOS scoring (4, 5), poor results in 31 (38.7%) cases, and 21 among those died (26.3%). Conclusions: Early evacuation with surgery results in a radical decrease in intracranial pressure and better prognosis. Patients with midline deviation >5mm, ventricular extension, hydrocephalus and reduced level of consciousness have worst prognosis.
Prevalence of Urinary Incontinence in Pregnant Women: A Cross Sectional Survey Study
Authors: Razzaq Rabia , Muhammad Atta , Shabbir Sidrah , Naeem Malhi Maria , Fatima Noor , Kiran Warda
Published: October 2022

Although urinary incontinence is not life threatening, it is burdensome physically, mentally, emotionally and economically. During pregnancy many factors like emotional changes mechanical, hormonal and circulatory changes, musculoskeletal changes are occurring in the pregnant women and causing pelvic pain and urinary incontinence. Objective: To determine the prevalence of urinary incontinence among pregnant women. Methods: A cross sectional survey study was conducted in Jinnah Hospital and Services Hospital Lahore. All those females who were in healthy pregnancy condition were included in this study. This convenient sampling was conducted in which sample of 323 were included with estimated population of 2000 women with 95% of confidence interval and 5% margin of error. In this study statistical analysis was done by using SPSS version 16. Results: Majority of females having age groups of 20 to 24 years and 25 to 29 years had mild problems of urinary incontinence. There were 14 subjects of age group 25 to 29 years that had moderate problem of urinary incontinence. There were 3 subjects of age group 25 to 29 years that had severe problem of urinary incontinence. Urinary incontinence was common in females having 2 or 3 previous pregnancies or multiparous females. Conclusions: Hence, it is concluded that urinary incontinence is very common in pregnant females. Majority of females from age group 20 to 29 years had mild problem of urinary incontinence. Its incidence was greater in those females having 2 or 3 previous pregnancies or multiparous females
An evaluation of antibiotic prescribing practices among dentists in Lahore: A cross-sectional study
Authors: Babar Palwasha , Virda Maryam , Haider Adeel , Alamgir Wajiha , Afzal Muhammad , Ahmad Khan Rana Muhammad
Published: October 2022

The appropriate use of antibiotics has become a major concern in healthcare. The over prescription and misuse of antibiotics has contributed to antibiotic resistance which has emerged as a major public health issue. Objective: The current study is conducted to investigate the antibiotic use by the dentists and to assess the conformity with evidence-based guidelines. Methods: A convenience sample of 216 dental practitioners were included in the study. A self-structured questionnaire was administered after getting consent from the participants. The questionnaire consisted of demographic details, self-reported usage of antibiotics in different clinical situations and questions exploring the practices regarding the use of antibiotics. Data were analyzed using SPSS version 24.0. Results: 87% of the participants prescribed antibiotics in irreversible pulpitis, 53.7% in dry socket and 78.7% in localized periapical abscess. Regarding their practice of antibiotic prescription, 77.8% participants reported the prescription of antibiotics in addition to the dental treatment for early resolution of the symptoms. 73.2 % reported that they fear the spread of infection if they have not prescribed antibiotics and 66.7% reported the use of antibiotics to defer the patient if the provision of treatment was not possible at the time. 68.9% participants reported that they would resort to some different antibiotic in case of persistent dental pain at the follow-up visit. Conclusions: The study shows indiscriminate and inappropriate use of antibiotics by the dentists. A lack of knowledge among the dental practitioners regarding the evidence-based clinical indications for antibiotics was evident.
Assessment of risk factors of Depression in the post-stroke phase of the stroke survivor patients: A cross-sectional study
Authors: Bhutto Amanullah , Hussain Tazeem , Ali Qureshi Amjad , Shah Shahnaz , Kumar Santosh , Lalchand .
Published: October 2022

Depression and mood changes are important complications of a stroke. A total of 30% of stroke survivors potentially develop depression, sooner or later. Despite its effect on the quality of life of the patient as well as functional recovery, it is often neglected resulting in a lack of treatment. However, regular antidepressant drugs play no beneficial role in the treatment of PSD. Objective: The present study aim is to the establishment of prevalence and factors responsible for causing post-stroke depression. Methods: The participants included in the study previously had strokes according to the definition given by WHO. Modified Motor Assessment Scale (MMAS) and Depression Anxiety Stress Scale-21 (DASS-21) were administered. Socio-demographic data of all the patients was collected. The risk factors were the laterality of the stroke, duration of the post-stroke phase, functional impairment after the stroke, and gender of the patient. Results: A total of 62 participants were included in the study. A total of 38 (61.29%) of the patients were male and 24 (38.71%) were female. The mean age of the patients was 51.86±5.3 years with a range of 41 to 63 years. Assessment through DASS-21 showed that 46 (74.19%) patients were normal and 16 (25.81%) were detected with depression. The statistically significant risk factors behind post-stroke depression (PSD) were gender and stroke laterality. However, the assessment through MMAS scores shows no significant participation of post-stroke disability and post-stroke duration in PSD. Conclusion: PSD is an important complication followed by stroke. Stroke laterality and gender are significant risk factors for PSD
Age, Gender and length of illness’s relation with Hepatic Dysfunction in individuals having Malaria: A cross-sectional study
Authors: Rafique Saima , Hussain Tazeem , `Rani Memon Faima , Iqbal Atif , Nazia Shaikh Shafaq , Kumar Narindar
Published: October 2022

With almost 200 million medical cases occurring each year, malaria is the most common vector-borne disease worldwide. Objective: To ascertain the relationship of hepatic dysfunction with age, gender, and length of illness in individuals with malaria. Methods: Data were gathered using a non-probability consecutive sampling method. A total of 270 patients are selected for a sample using the Open Epi program, ranging in age from 25 to 65 and of either gender. Patients who tested positive for malarial parasites and had fever >104°F for longer than 4 days accompanied with chills, and rigors were selected. Patients with undiagnosed hepatomegaly and hepatic cirrhosis were excluded. Samples of blood were gathered and delivered to the pathology lab for biochemical evaluation. SPSS version 16.0 was used for data entry and analysis. For the numerical variables (such as age of the patients and disease duration), means and standard deviations were computed. The subjective variables (gender, age groups, length divisions, and hepatic dysfunction) were evaluated as percentages and frequencies. Results: A total of 270 individuals with confirmed cases of malaria were examined, having a mean age of 39.97 + 8.91 years. There were 70 (27.5%) women and 185 (72.5%) men. A total of 100 (37.3%) individuals with malaria had hepatic impairment. The only factor that significantly correlated (p0.03) to hepatic dysfunction was the length of the illness, whereas gender and various age categories did not. Conclusions: Only the length of the illness revealed a strong relationship between malaria and hepatic dysfunction in our research's findings (p 0.03).
Impact Of the Covid-19 Pandemic on The Prevalence of Thoracolumbar Vertebral Compression Fractures in Elderly People
Authors: Ali Qureshi Amjad , Mujahid Sharif Muhammad , Ujjan Badar Uddin , Latif Memon Musadique , Ullah Saeed , Aamir Shah Syed
Published: October 2022

Covid-19 had a profound effect on many parts of life during 2020. Our country, much like the majority of other nations across the globe, saw a Covid-19 epidemic, a wave reaching its height from the middle of March through April of 2020. This brought about significant difficulties for our civilization in a variety of spheres, including the medical, social, and economic spheres. On February 27th, the first patient in our country to be diagnosed with Covid-19 was identified. Objective: To evaluate the Covid-19 effect on the prevalence of thoracolumbar vertebral compression fractures in elderly people. Methods: A total of 172 individuals with vertebral compression fractures (VCF) were above the age of 65 years. The age and gender of the patients were comparable across the two research groups. Only those people who exhibited symptoms for less than four weeks were taken into account. We analyzed every patient's medical records and obtained all essential data, including demographics (gender, age, and compression fracture risk factors), fracture mechanism, and location of the fracture. Results: In 2020, we observed a greater percentage of high-energy VCF (10.5% versus 6.7%). In 2020, there were 7.5 times more recurrent fractures and the proportion of Ankylosing Spondylitis was much higher. Similar admission rates to VCF ED were observed, with 60% receiving conservative care. The number of procedures performed on admitted patients increased in 2020 (66.7% vs. 60%, P =.71), and PBK plus fixation tended to be more common in 2020 compared to 2018-19 (15.8% versus 7.5%, P =.29). In the Covid-19 epidemic, the RR for BKP Plus fixation vs. BKP alone was 1.95, indicating increased risks for difficult operation. In 2020, there were significantly more complications (18.4% vs 3.7%, P.001). Time to surgery also increased somewhat in 2020, from 6.25 days to 5.3 days (P =.55), and admission duration increased marginally (12.2 days vs. 9.9 days, P =.27). Most of the patients choose home treatment over inpatient care during the Covid-19 pandemic (72.2% vs. 58.8%). Conclusions: The frequency of VCF did not vary as a result of the Covid-19 pandemic; nevertheless, the features of patients did change, which had an effect on hospitalizations, institutional rehabilitative services, and a predilection for extensive surgery as opposed to BKP alone. Although it is not yet known whether or not COVID-19 will continue to be a problem in the years to come, the effects and lessons it has provided are still valuable.
Role of dietary pattern in infertility among married women
Authors: Imran Rabia , Khalid Sidra , Huda Noor-ul- , Bashir Shahid , Aslam Maria , Jabeen Shaista
Published: October 2022

Infertility is one of the leading disorder and effecting large number of population. Imbalanced dietary pattern can disturb fertility in women. The diet we consumed has huge input in the occurrence of fertility or infertility in women. Objective: To determine the role of dietary pattern in the occurrence of infertility among married women. Methods: Cross-sectional study was conducted in public sector hospital of Lahore on 100 infertile females from reproductive age to premenopausal years of life in married women. Results: Age group ranges from 27-32 years’ female were infertile. 56/100 females consumed refined carbohydrate and 89 out of 100 consumed sugar daily in diet. Several dietary factors were found to be involved in infertility among women. Conclusions: It has been concluded that imbalanced dietary routine can directly cause infertility in women of various age. Women who consumed refined carbs, high fat and low dairy items, thus results in failure to thrive a successful pregnancy.
Clinical Outcomes of Pulmonary Resections for Benign Lung Diseases in Adults
Authors: Shoaib Lodro Muhammad , Ahmad Tanveer , Mazcuri Misauq , Abid Ambreen , Ali Nadir
Published: October 2022

Benign lung diseases (BLD) are a spectrum of diseases that require medical and surgical attention. Surgical treatment in majority cases provides curative treatment in majority of the cases. Objective:  To assess the clinical outcome in patients who undergo pulmonary resection for various indications in BLD. Methods: A prospective study was conducted in The Department of Thoracic surgery at Jinnah Postgraduate Medical Center, Karachi from June 2021 to June 2022. All symptomatic patients above the age of 12 years with radiological evidence of resectable lung disease with good cardiopulmonary reserve were included. Results: Eighty-four patients were included; sixty-six (78.6%) were males. Most common indication for resection was bronchiectasis (n=32; 38.1%) and aspergilloma (n=22; 26.2%). Majority of the patients presented with productive cough (44; 52.3%), chest pain (41; 48.8%) and hemoptysis (28;33%). Eighteen (81.8%) out of 22 patients of aspergilloma were complex in nature. Lobectomy (67; 78.8%) was most commonly performed followed by wedge resection (10; 11.7%). Forced vital capacity (FVC) and forced expiratory volume in one second (FEV1) both were significantly improved after lung resection (p˂0.001). The most common complications were post resection fluid (n=12; 14.2%), residual pleural space (n=10;11.9%). Three patients (3.6%) died; two (2.38%) due to respiratory failure and one (1.2%) after myocardial infraction. Conclusions: Despite limitations, lobectomy and lesser pulmonary resections are safe procedures when patients are carefully selected and prepared. Management in a dedicated Thoracic Surgical unit is essential to keep the complication rate under control and patients should be assessed for symptomatic (spirometric) and radiological improvement on follow up visits to document ongoing clinical improvement for an improved quality of life
Prevalence Of Piriformis Muscle Syndrome Among Individuals with Low Back Pain
Authors: Islam Farooq , Mansha Hamza , Gulzar Khushboo , Raza Asim , Raffique Awais , Haider Saqlain
Published: October 2022

Piriformis syndrome is a condition in which the piriformis muscle, located in the buttock region, spasms and causes buttock pain. The piriformis muscle also can irritate the nearby sciatic nerve and cause pain, numbness and tingling. Starts at the lower spine and connects the upper surface of each femur (thighbone). Functions to assist in rotating the hip and turning the leg and foot outward Runs diagonally. Objective: To find out the prevalence of piriformis muscle syndrome among individuals with low back pain. Methods: Participation of population from Gujranwala city from various emergency clinics was remembered for this study in view of inclusion and exclusion criteria. The data was collected through non-probability convenient sampling technique. Affirmed instances of low back torment patients were added and get some information about their agony as indicated by VAS (visual simple scale) and outer muscle tests (FAIR test, pace sign, Piriformis stretch (test) were performed on patients. Results: The results have been obtained from 219 participants. The overall Prevalence of piriformis muscle syndrome among individuals with low back pain was 18.3%.The Mean±SD of exact BMI were 27.43±6.859. Out of 219 patients, male and female Pace sign were respectively (85.8% negative and 14.2% positive). (81.7%) Negative and (18.3%) Positive Prevalence of piriformis muscle syndrome in the general population in Age groups chi-square value is (47.753b) and P- Value (<0.001*). Conclusions: In this research, the positive prevalence rate is 18.3%. It demonstrates that several individuals with low back pain have piriformis muscle syndrome.
Struktur Pasar Industri Konstruksi Di Indonesia Tahun 2018-2021
Authors: Dinarjito Agung
Published: October 2022

Industri konstruksi dan bangunan saat ini menjadi salah satu industri yang sangat penting untuk menunjang pertumbuhan ekonomi. Industri konstruksi dan perumahan yang saat ini menjadi industri prioritas untuk memenuhi kebutuhan dasar masyarakat. Penelitian ini bertujuan untuk mengetahui struktur pasar industri konstruksi di Indonesia untuk tahun 2018-2021. Penelitian ini menggunakan data sekunder yang berupa laporan keuangan dan laporan tahunan perusahaan sub industri konstruksi dan bangunan tahun 2018-2021. Untuk melihat struktur pasar tersebut digunakan pengukuran rasio konsentrasi (CR4) dan Indeks Herfindahl-Hirschman (IHH). Berdasar hasil penelitian disimpulkan bahwa bentuk pasar industri konstruksi di Indonesia tahun 2018-2021 adalah pasar oligopoli ketat.
Apakah Revolusi Industri 5.0 Dapat Menghilangkan Profesi Akuntan?
Authors: Prakosa Dani Karismawan , Firmansyah Amrie
Published: October 2022

Profesi akuntan memiliki peran yang sangat penting di berbagai entitas dan sektor. Penelitian ini bertujuan untuk menguji eksistensi profesi akuntansi terkait dengan hadirnya era revolusi industri 5.0. Penelitian ini menggunakan metode kualitatif dengan pendekatan scoping review. Dari hasil telaah, diketahui bahwa revolusi industri 5.0 akan mentransformasi peran profesi akuntan ke level penciptaan nilai yang lebih tinggi. Namun demikian, terdapat beberapa tantangan yang dihadapi para akuntan, diantaranya terkait kemampuan mereka untuk beradaptasi dengan perubahan yang cepat, pergeseran kebutuhan klien dan pemberi kerja, peningkatan kompetensi diri, penguasaan teknologi, dan kompetisi yang semakin luas. Penelitian ini mengidentifikasi beberapa keterampilan kunci yang diperlukan oleh para akuntan untuk dapat bertransformasi ke peran mereka yang baru, diantaranya seperti literasi teknologi, kemampuan analitis dan berpikir kritis, kefasihan berkomunikasi, kemampuan beradaptasi, dan mengelola emosi. Untuk mengawal kesuksesan transformasi ini, diperlukan kolaborasi dari badan profesi akuntan, pemerintah, dan penyusun standar.
THE RISE OF HOPS IN HINDUSTAN
Authors: Chittibomma Karthik
Published: October 2022

Hop shoots are also called as hops and scientifically known as Humulus lupulus belonging to the family Cannabaceae are native to the North American temperate. These plants are crawlers and can grow up to 30 feet height. Its flowers are widely used in breweries due to their unique flavor and aroma. The bitter tase and aroma of beer is due to the hops as they balance the sweetness in beer. This plant also has anti-cancer properties, rich in IPA (iso propyl alcohol) and also used in curing fatty liver disease and tuberculosis disease. Hops have been recently cultivated in India. The brewing industry of India has a new raw material for the preparation of alcoholic beverages. These hops have anti-cancer properties therefore minorly helps in reducing the risk of liver cancer and liver cirrhosis. A farmer named Amarendar Singh is going to be the first known farmer to cultivate this crop successfully and Bihar becomes the first state in India cultivating the hops. Scientists are investigating its characteristics and conducting trails. Key words: Brewery, Strobile, Economical crop, Hopfield, Oleoresin, Hop house, flavonoids.
OCCURANCE OF N. viridula (Order- HEMIPTERA)) FROM SANGOLA, DIST.SOLAPUR (MS)
Authors: A. M Bhosale
Published: October 2022

Nezara viridula (L.) is a cosmopolitan, polyphagous heteropteran that causes economic damage to many crop species. It is predominant in most of the warmer regions, damaging a wide variety of fruits. In the present study, N.viridula insect pest was recorded for the first time. It belongs to the family Pentatomidae . This is a polyphagus vegetable pest that mainly occurs on brinjal and okra vegetable crops. It is a sap-sucking insect pest that causes severe damage and economic losses. Key words: Occurance, N. viridula, vegetables, insect pest.
Intelligent System using Flex Sensor for the Assessment of Parkinson's Disease
Authors: Journal IJSREM
Published: October 2022

Parkinson's disease is a progressive nervous system disorder that affects movement which is prevalent in a large number of the world’s population and progressively deteriorates over time. A prognostic system using flex sensors was used to detect tremors in people to assess the severity, progression and chances of regression of the disease. The electronic components used are: an Arduino Nano, five novel flex sensors made of a carbon material known as velostat and a glove onto which the sensors are attached at each finger to record movements and bending. The glove is worn by the patient and every time a tremor is detected; sensors send signals to the Arduino which are converted to bend angles using the change in resistance. The tremor signals are sent in the form of resistances and then converted to voltage. The voltage is then plotted as a function of the bend angle of the flex sensor. A threshold was determined using the sudden and rapid tremors, causing a change in resistance from which the severity and stage of Parkinson’s in the patient can be inferred. This system can be useful for patients who have come out of therapy but still have recurring symptoms.
Process Parameter Optimization of Laser Beam Machining for SS-304
Authors: Kasbe Amol
Published: October 2022

This paper presents an investigation and optimization of process parameters of laser beam machining process on SS-304. LBM uses the light energy from a laser device for the material removal by vaporization and ablation. In the present study, attempt is made to find the optimal machining conditions with Taper (T) and surface roughness (Ra) as objective. It was observed that with increase in laser power, taper and surface roughness increases. Response surface methodologies D optimality test was used to determine the optimal machining parameters, among which the laser power and the cutting speed were found to be the most significant. It was observed that lower laser power and cutting speed is suitable for better taper and surface roughness. Key Words: LBM, RSM, SS-304
Chronic obstructive pulmonary disease: structure prediction of pulmonary surfactant associated protein 1
Authors:   Department of Zoology, M.R.K College of Arts and Science, Palanchanallur, Kattumannarkovil, Tamil Nadu, Glory Ruba , K Palanivelu ,   Department of Zoology, M.R.K College of Arts and Science, Palanchanallur, Kattumannarkovil, Tamil Nadu
Published: October 2022

Biological research is significantly impacted by bioinformatics. Without the bioinformatics component, massive research endeavors like the human genome project would be worthless. After the raw data is available, in silico testing of hypotheses is possible. A form of obstructive lung illness called COPD is characterized by persistently inadequate airflow. Shortness of breath and a cough that produces phlegm are the prominent symptoms. Usually, it gets worse with time. It will eventually be challenging to carry objects or climb stairs. COPD is the primary diagnosis for chronic bronchitis. The most frequent cause of COPD is tobacco use, with other variables such as air pollution and genetics having a lesser impact.
Proximate and physicochemical composition of marine red seaweed Portieria hornemannii against anti diabetic activity
Authors:   Ethanopharmacological and Algal Biotechnology Laboratory, Department of Botany, School of Life Sciences,  Periyar University, Periyar Palkalai Nagar, Salem-11, Karuppannan Saranya , Palani Kokila ,   Ethanopharmacological and Algal Biotechnology Laboratory, Department of Botany, School of Life Sciences,  Periyar University, Periyar Palkalai Nagar, Salem-11, Palaniappan Nithya ,   Ethanopharmacological and Algal Biotechnology Laboratory, Department of Botany, School of Life Sciences,  Periyar University, Periyar Palkalai Nagar, Salem-11, Lakshmanan Archana ,   Ethanopharmacological and Algal Biotechnology Laboratory, Department of Botany, School of Life Sciences,  Periyar University, Periyar Palkalai Nagar, Salem-11, Maluventhan Viji ,   Department of Botany, Thiagarajar College, Madurai – 625009, Tamil Nadu, India, Arumugam Maruthupandian ,   Ethanopharmacological and Algal Biotechnology Laboratory, Department of Botany, School of Life Sciences,  Periyar University, Periyar Palkalai Nagar, Salem-11
Published: October 2022

The proximate composition (Protein, carbohydrate, lipid, ash, moisture and total dietary fiber content) and physicochemical properties of Portieria hornemannii were studied. The proximate composition of protein 33.82 ± 1.48 followed by carbohydrate and lipid the protein is highest activity. Total dietary fiber contained 2.24 ± 0.39 for thr red seaweed of Portieria hornemannii contains neutral sugars corresponded to sulphated galactoans (Carrageen and agar). Insoluble fiber 1.22 ± 0.06 and soluble fiber 1.02 ± 0.05, moisture and ash were 12.96 ± 0.55 and 18.42 ± 1.03 respectively. Followed by WHC and swelling both had strong physicochemical characteristics at high temperatures. The oil retention is very low. Finally the seaweed P.hornemannii is used in anti diabetic activity of α amylase enzyme activity IC50 value 121.68. The P.hornemannii can be effective inhibition of anti diabetic activity and its leads to develop the natural drug in pharmaceutical application
T cell receptor excision circles (TRECs) and kappa-deleting recombination excision circles (KRECs) as markers of early T cell and B cell immune recovery after haematopoietic stem cell transplantation (HSCT)
Authors:   Department of Clinical Pathology, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Elghazawy Mahmoud , Talkhan Hala ,   Department of Clinical Pathology, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Ghareeb Hala ,   Department of Clinical Pathology, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Samaha Dalia ,   Department of Clinical Pathology, Faculty of Medicine, Ain Shams University, Cairo, Egypt., El-Zimaity Maha ,   Department of Internal Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Salem Lamyaa ,   Department of Clinical Pathology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Published: October 2022

Hematopoietic stem cell transplantation (HSCT) is a key therapeutic strategy for a number of hematological malignancies and non-malignant disorders of the hematopoietic system. One of the most important events post SCT is the immune system reconstitution—a process characterized by a considerable dynamic and is critical in promoting overall survival of transplant patients, restoring immune protection from opportunistic infections, and mediating an alloreactive graft-versus-tumor effect against residual malignant disease. T cell receptor excision circles (TRECs) and Kappa deleting recombination excision circles (KRECs) are byproducts of T cells and B cells receptor recombination processes, respectively and can be used in monitoring denovo synthesis of T cells and B cells post SCT. The aim of this study was to determine the role of combined TRECs and KRECs quantitation in follow up of allogenic HSCT patients through testing samples at 1, 3 and 6 months post-transplant as well as their role in predicting outcomes of transplantation. The study was conducted on 32 patients receiving allogenic HSCT from an HLA identical sibling. Combined quantification of TRECs and KRECs in the genomic DNA of peripheral blood mononuclear cells was performed using quantitative real-time PCR using a standard curve. TRECs and KRECs levels were inversely related to age and significantly lower in patients transplanted for malignant diseases than benign diseases (p <0.05). TREC levels could predict relapse as an outcome and graft versus host disease (GvHD) at 6 months posttransplant. In conclusion, age and nature of disease determined TRECs and KRECs levels posttransplant. In addition, monitoring immune reconstitution using combined TRECs/KRECs quantitiation by real time PCR may be informative and could help predict outcomes of transplantation in allogenic HSCT.
Skin colonization of Staphylococcus aureus harboring superantigen toxin genes and its correlation with serum IL-22 level in psoriasis patients
Authors:   Department of Medical Microbiology & Immunology, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Fouad Nancy , Mostafa Fatma ,   Department of Medical Microbiology & Immunology, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Soltan Marwa ,   Department of Dermatology & Andrology, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Zaki Ali ,   Department of Medical Microbiology & Immunology, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Rania Rania ,   Department of Medical Microbiology & Immunology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Published: October 2022

Psoriasis is a chronic debilitating skin disease with an estimated prevalence reaching 2% of the worldwide population. Psoriatic disease is driven by the interactions among innate and adaptive immune systems with structural components of the skin. Interleukin (IL)-22 mediates keratinocyte proliferation and epidermal hyperplasia, and changes in the structure of skin flora can play a role in the secretion of IL-22. The aim of this study was to correlate serum levels of IL-22 and Staphylococcus aureus toxins with disease activity in plaque psoriasis. The study group included 50 patients with mild, moderate, and severe psoriasis. The control group comprised 20 sex- and age-matched apparently healthy volunteers. IL-22 concentration was assessed in sera of patients and the control group by using the ELISA technique. The serum levels of IL-22 in patients were higher than in the control group, but the difference was statistically insignificant (P=0.413). Serum IL-22 levels were positively correlated with the Psoriasis Area and Severity Index (PASI) score of psoriasis patients (P=0.0003). The IL-22 serum levels in patients colonized with toxigenic strains of S. aureus were significantly higher than in patients colonized with non-toxigenic strains (P= 0.028). In conclusion, IL-22 plays a role in the pathogenesis of psoriasis, and its secretion can be triggered by the toxins produced by S. aureus colonizing the skin of patients.
High-Flux dialyzer 2.6 m2 is promising for free light chains removal in high-flux hemodialysis and in hemodiafiltration
Authors:   Department of Internal Medicine & Nephrology, Faculty of Medicine, Ain Shams University, Cairo, Egypt., El-Sayed Hesham , Waleed Waleed , Shaimaa Shaimaa , Emara Shaimaa , Sultan Reem , Magdy Magdy ,   Department of Internal Medicine & Nephrology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Published: October 2022

Department of Internal Medicine & Nephrology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
SHOCK HIPOVOLÉMICO
Authors: Saquicela Espinoza Luis Alberto , Muzha Arevalo Carla Samantha , Naula Macancela Bryan Eduardo , Vázquez Lituma Sofia Belén
Published: October 2022

El shock hipovolémico se define como un estado de hipoperfusión tisular, que puede ser hemorrágico y no hemorrágico, producido principalmente por traumatismos y sangrados, donde los accidentes de tránsito y las caídas destacan como las principales etiologías. Al hablar de su fisiopatología, se debe destacar que en este tipo de shock el sangrado es el rasgo principal y la extensión del daño a tejidos blandos determinará si se trata de una entidad hemorrágica o no hemorrágica. Lo esencial es reconocer el grado clínico de shock del paciente, por ello setomará como referencia la Guía ATLS del 2020 y Escala Davis. Un punto clave es saber cómo diagnosticar al paciente, por lo cual una correcta anamnesis, exploración física y los exámenes complementarios serán de gran ayuda en reconocer lesiones que comprometan la vitalidad, así como la revisión constante de los signos vitales, estado neurológico, diuresis, con el objetivo de mantener la volemia del paciente. La fluidoterapia administrada en forma temprana es la piedra angular del tratamiento del shock hipovolémico, en la práctica clínica el líquido de elección en el shock hipovolémico de tipo hemorrágico es el Lactato de Ringer que pertenecen a la familia de soluciones cristaloides, este contribuye en la expansión intravascular transitoria estabilizando la volemia desplazando el líquido a los espacios intersticial e intracelular. Los fármacos vasopresores más utilizados son norepinefrina, dopamina y epinefrina, el fármaco inotrópico por excelencia es la dobutamina empleada por su efecto vasodilatador y en signos de hipoperfusión.
APENDICITIS AGUDA
Authors: Zambrano Párraga Enma Jacqueline , Morejón Flores Génesis Dayana , Pesantez Méndez Jenny Gabriela
Published: October 2022

La apendicitis aguda es una patología que con frecuencia es asociada a dolor abdominal, misma que se origina como consecuencia de la inflamación del apéndice, posterior a una obstrucción o taponamiento de la luz apendicular. Se presenta usualmente en pacientes jóvenes (11-20 años), sin embargo, ninguna edad es inmune a esta patología, se estima una incidencia de 100 a 151 por 100.000 personas en América del Norte, Europa del Este y Europa Occidental y una tasa de mortalidad alrededor de 0,25%, siendo el sexo femenino el más frecuente. Esta patología suele caracterizarse por dolor visceral, periumbilical, epigástrico, y a nivel de fosa iliaca derecha; así como signos de irritación peritoneal y obstrucción del flujo vascular. El diagnóstico y manejo de la apendicitis aguda continúa siendo un desafío para los cirujanos, puesto que, existe controversia en tornoa los medios de diagnóstico que se manejan en base a escalas diagnosticas como la de Alvarado o RIPASA, la experiencia de los tratantes en la clínica de la patología, exámenes paraclínicos, o exámenes de imagen operador dependiente; así como el tratamiento más idóneo, ya sea este enfocado en agentes antibacterianos o en el abordaje quirúrgico correspondiente a la apendicectomía. Por ello, el diagnóstico diferencial de un apéndice anormal incluye otras condiciones que a menudo se presentan con signos y síntomas que coinciden con la clínica de apendicitis aguda. En este capítulo, repasamos la patogenia, las manifestaciones clínicas, así como el diagnóstico y manejo característicos de una apendicitis aguda.
LIQUIDOS Y ELECTROLITOS
Authors: Ortega Castillo Susan Karina , Aguaiza Rivera Estefanía de Rocío , Chillogallo Ochoa Joel Alexander , Veliz Vargas Xaviera Patricia
Published: October 2022

Los líquidos y electrolitos forman parte de un papel fundamental en un paciente quirúrgico, siendo así de gran importancia para el manejo durante el periodo preoperatorio, durante la cirugía y posterior a ella debido a los cambios que pueden existir en los volúmenes de los mismos. El agua es un componente esencial en el ser humano, representando así el 60% aproximadamente de la masa corporal en los adultos y hasta un 80% en los jóvenes, de este porcentaje los 2/3 corresponden al espacio intracelular y el 1/3 al extracelular. Conocer sobre la distribución de los diversos compartimientos a nivel corporal es indispensable debido a que permite al médico evaluar y prevenir alteraciones a nivel de líquidos o electrolitos e individualizar a cada paciente de acuerdo a sus requerimientos y de esta manera poder administrar los fluidos adecuados. Las soluciones utilizadas para administrar por vía endovenosa se clasifican en cristaloides y coloides siendo su principal diferencia que la una tiene la capacidad de atravesar una membrana dada mientras que la otra no. Los electrolitos son sustancias que están presentes en la sangre y demás líquidos a nivel corporal mismos que poseen una carga eléctrica ya sea positiva o llamados cationes como el sodio, potasio o magnesio,y los de carga negativa o aniones tales como el cloro, bicarbonato, etc. Identificar las alteraciones que se producen ya sea por valores elevados o disminuidos de cada electrolito deben ser identificadas de manera inmediata para evitar complicaciones que pongan en riesgo al paciente.
ENFERMEDADES DE LA VESÍCULA BILIAR Y COLÉDOCO
Authors: Vélez Chávez Lady Elizabeth , Soto Jaramillo Diana Elizabeth , Urgiles Campoverde Wendy Jazmín , Carrillo Velasco Génesis Pauleth
Published: October 2022

La vesícula biliar y colédoco cumplen un papel importante en cuanto a la digestión, al no funcionar correctamente engloban diversas patologías muy comunes y conocidas en la emergencia médica, de las cuales debemos hacer rápidamente un diagnóstico diferencial entre las cuatro enfermedades gastrointestinales más usuales, la cual puede tratarse de una colelitiasis, colecistitis aguda o crónica, colangitis,coledocolitiasis o quistes biliares.La incidencia varía dependiendo de cada una de estas patologías, en la colelitiasis es más común en mujeres y representa del 10-30% de casos anuales, mientras que en la colecistitis va a depender si desarrolla una colecistitis aguda o crónica, siendo más común en hombres; en cuanto a la coledocolitiasis su incidencia se da mas en pacientes mayores con antecedentes previo de colecistitis; a nivel de la colangitis esta ha disminuido gracias a la intervención quirúrgica enla vía biliar, representando un 0.5%-2.4% de casos y finalmente un 80% presentan quistes biliares con mayor frecuencia en pacientes pediátricos.En la actualidad el tratamiento de la VB, independientemente de la patología que presente determina si puede ser tratado de una forma no/si quirúrgica, como es en la colecistitis, su diagnóstico y tratamiento se basa según los criterios de Tokio, la cual determinar el grado de severidad de la VB para así indicar si el paciente debe ser intervenido quirúrgicamentepor medio de una cirugía abierta o laparoscópica.