bluuebunny/crossref_metadata_2025 huggingface dataset:
Afectación auditiva en personal expuesto a ruido industrial en una empresa manufacturera
Authors: Alcivar Tejena Genesis Monserrate
Published: October 2024

La exposición diaria a ruido industrial en el lugar de trabajo puede ocasionar como resultado afectaciones auditivas en diversos niveles, el objetivo de esta investigación es identificar la incidencia de la afectación auditiva en el personal expuesto al ruido industrial en una empresa manufacturera, para ello se realizó un estudio de cohorte retrospectivo de carácter observacional en el que se analizaron los resultados de las audiometrías, porcentaje de pérdida auditiva (cd 513) y antigüedad laboral de 138 trabajadores expuesto a ruido industrial en el año 2021, los resultados demuestran predominio en las características demográficas; género masculino con 91.3%, grupo etario de 40 a 50 años y una exposición laboral a ruido industrial del 72.5% con más de 9 años en el puesto, un pequeño porcentaje (2.9%) de los trabajadores presentaron una afectación auditiva leve de ingreso,  mientras que en las audiometrías actuales un 11.6% de los trabajadores presentaron una afectación auditiva leve, 1.4% una afectación auditiva moderada y el 0.7% una afectación auditiva avanzada según la clasificación de klockhoff modificado. Se concluye que hay una correlación entre la exposición laboral a ruido industrial y afectación auditiva; a mayor tiempo de exposición mayor afectación siendo esta afectación mínima en la población estudiada.
Organizational Capabilities of Retail Companies to Develop Green Marketing Strategies
Authors: Escalera Chávez Milka Elena , Vargas-Hernández José G. , García-Santillán Arturo
Published: October 2024

The human being has damaged the planet by the indiscriminate consumption of products that are not friendly to the environment, hence now the trend of consumers to choose sustainable products. This is the reason why companies are changing the way they make their products, as well as the style of communication to inform that their products are favorable to the environment. The scope of this work is to assess retail enterprises ability for developing green marketing strategies. The study is quantitative-exploratory based on a non-probabilistic sample. A questionnaire was applied to 30 business owners and/or managers. Data was analyzed by using the principal components method. It was observed that the retail companies in Rioverde city, San Luis Potosí (S.L.P.) are able to develop green marketing strategies. The correlation matrix shows acceptable correlations and the values of the Sample Adequacy Measure (MSA) values are greater than 0.500: These values allow corroborating that the data structure is adequate to be examined by factor analysis. The analysis detects two latent factors that together explain 69.18% of the common variance. The results indicate that green marketing strategies require that owners or managers reformulate their business and processes from different perspectives: internally and with their customers. With respect the first point, staff must be trained on the importance of ecological products for the environment, health and the benefits for the company. With reference to, the second point, the owner or manager must identify the specific market for these products, because customers are varied and with different needs.
Diseño pedagógico instruccional para carreras en línea. Uso de recursos didácticos en educación básica
Authors: Alpizar Jorge Luis , Henríquez Coronel María Angélica , Naranjo Flores Christian Alberto
Published: October 2024

El diseño pedagógico instruccional para las carreras en línea aplicado en la UTM se estructura a partir del uso de la plataforma Moodle y consta de ocho (8) recursos básicos. La presente investigación se desarrolló con el propósito de conocer el uso que hacen los estudiantes de los diferentes recursos que se ofrecen en las aulas de las asignaturas. Se hizo acopio y análisis de la información generada por la plataforma para los tres primeros niveles de la carrera de Educación Básica durante uno de los períodos académicos del año 2020. Los resultados indican que los recursos más utilizados son las tareas, los test que se hacen al finalizar cada unidad y los compendios. En contraste, los recursos que tienen menos interacciones por parte de los estudiantes son los materiales complementarios, las presentaciones gráficas y los videos de las clases realizados por el autor y tutores de los cursos, para explicar los temas y actividades de cada unidad. El análisis de los resultados permite orientar de manera apropiada la preparación de estos recursos en procura de incrementar su uso, efectividad y la importancia que se le otorga por los estudiantes a los mismos.
Uso de plataformas virtuales por profesionales de enfermería para educar al paciente oncológico
Authors: Lermo Sandoval Jenny Ivonne , Calixto Cruz Erika Patricia
Published: October 2024

La educación es una actividad trascendente para lograr promover el cuidado del paciente oncológico, es así que el uso de las plataformas virtuales se han convertido en herramientas que favorecen la conectividad, mantienen la posibilidad del contacto continuo con el paciente para dar soporte necesario y promover su autocuidado; además de reducir los costos y tiempo. Este estudio tiene como objetivo, analizar el desarrollo de las evidencias científicas sobre educación de enfermería a través de plataformas virtuales a los pacientes oncológicos. La metodología fue una revisión integrativa, utilizando 6 bases de datos: PudMed, Alicia, SciELO, Embase, DOAJ y Google Académico. Se incluyó artículos en inglés y español de los últimos 7 años. Los resultados encontraron 22 artículos sobre  recursos digitales, siendo medios que proporcionan información y educación; por lo que la enfermera debe aplicar estrategias pedagógicas para asumir el autocuidado en los pacientes oncológicos. Es importante resaltar que la educación debe estar de acuerdo al tipo de paciente tanto en la virtualidad y en la presencialidad. Se concluye que los enfermeros pueden incluir en las actividades cotidianas las prácticas educativas, utilizando los recursos digitales para sostener el autocuidado del paciente oncológico, favoreciendo su bienestar y calidad de vida.
Patrones de diseño en el modelo computacional del proceso de ingreso a la educación superior cubana
Authors: García Ojalvo Irina , Sepúlveda Lima Roberto , Abelló Ugalde Isidro Alfredo
Published: October 2024

El continuo perfeccionamiento de las políticas de acceso a la educación superior cubana, hace necesario contar con un sistema informático flexible, tanto para su mantenimiento como para su evolución, que permita responder más eficientemente a los cambios que se suceden cada curso escolar. El presente trabajo tiene el objetivo de analizar el uso de patrones de diseño en la concepción de un modelo computacional del proceso de ingreso. Se presenta la dimensión operacional del modelo elaborado teniendo en cuenta varios de los patrones referidos en la literatura. Se realizó una consulta a expertos en el desarrollo de software para valorar la conveniencia de utilizar estos patrones. Como resultado se obtuvo que más del 70% apreciaron este uso como muy adecuado o bastante adecuado. En la práctica el uso de patrones de diseño ha permitido desarrollar un sistema informático capaz de evolucionar según los cambios que ha tenido el proceso de ingreso a través de los años.
El principio de favorabilidad más allá del quantum de la pena
Authors: Muñoa Vidal Tania , Villacreses Palomeque Jorge Luis
Published: October 2024

El presente artículo de reflexión teórica analiza el principio de favorabilidad en el proceso penal, en virtud de que la doctrina y la norma jurídica entienden restringido el ámbito de aplicabilidad de ley más favorable a casos de conflictos entre leyes vigentes o de vigencia sucesiva respecto al momento de la comisión del delito, y otorga sólo significado a la favorabilidad en la relación entre los términos de la pena desde su aspecto cuantitativo. El enfoque de investigación cualitativa, mediante la revisión documental y bibliográfica, con apoyo en los métodos inductivos-deductivos, de análisis y síntesis, y exegético jurídico, permitieron reflexionar de forma teórica en la materia. Los resultados exhiben la validación de lo afirmado por la autora respecto a considerar que los temas de favorabilidad deben alcanzar no solo el conflicto de normas a resolverse desde la valoración del quantum de la pena, sino también otras instituciones jurídicas de carácter sustantivo y adjetivo. Lo que permitió concluir, que la visión del principio de favorabilidad contraído solo a la aplicación de pena más benigna, limita los derechos del sujeto pasivo del proceso penal si su aplicación no se extiende más allá de la valoración del quantum de la pena.
Alfabetización informacional y competencia digital en la gestión pedagógica docente
Authors: Mendoza Muñoz Gretty Katiuska , Párraga Muñoz Sonia Monserrate
Published: October 2024

La competencia digital docente es el conjunto de conocimientos, capacidades, habilidades y destrezas relacionadas con el uso de la tecnología para generar aprendizajes significativos que aportan a la gestión pedagógica. La presente investigación tiene como objetivo analizar la gestión pedagógica de aula a partir de la competencia digital docente con énfasis en la alfabetización informacional. Este estudio es cualitativo y cuantitativo, la información fue recolectada a docentes y directivos de Unidades Educativas del Estado por medio de una encuesta, además se aplicó una entrevista a dos expertos. En los resultados se evidencia un considerable nivel de colaboración e intercambio de información entre los docentes para el manejo de las tecnologías digitales y tienen interés por aprender e incluir dichas herramientas en la gestión pedagógica, sin embargo, poseen un escaso nivel en el desarrollo de las habilidades de alfabetización informacional. Se concluye que los docentes deben emplear un modelo tomando en cuenta las competencias de saber identificar, localizar, almacenar, organizar y analizar la información a través de los buscadores de la web, evaluando su finalidad y relevancia en la adquisición de conocimientos
Decomposition of Polythene by Bacteria Isolated from Waste Disposal Sites in Gusau City
Authors: Rosemary Okoye , Aliyu Sa’adatu
Published: October 2024

The accumulation of polythene can be hazardous and can cause various environmental problems. This work was aimed at studying the biodegradation of polythene by bacteria isolated from waste disposal areas in North West, (Zamfara state) Nigeria. A total of twenty soil samples were collected from four different locations, such as waste disposal areas, hospitals, roadsides, and petrol pumps station. Spread plate method was carried out on Nutrient agar for the growth of bacteria. A total of 13 bacteria were isolated from different areas. The total bacteria count in hospital ranged from 80 × 10-4 - 248 × 10-4 cfu/mL, roadsides ranged from 116 × 10-4 - 208 × 10-4 cfu/mL, petrol pump ranged from 88 × 10-4 - 184 × 10-4 cfu/mL and waste disposal areas ranged from 116 × 10-4 - 264 × 10-4 cfu/mL. The microbial species associated with the polythene materials were identified as Pseudomonas sp, Bacillus sp, Staphylococcus aureus, Providencia stuartii, Clostridium perfringes, Corynebacterium diphtheria, Listeria monocytogen. The bacteria isolates were screened for polyethylene degradation using mineral salt medium containing polyethylene as sole source of carbon and nitrogen for their ability to degrade polyethylene for the period of 2 months. The efficacy of the microbes in the degradation of polythene were analyzed using liquid culture method, among the bacteria Pseudomonas aeruginosa degraded 75% of polythene, Bacillus subtilis 71.4% in a period of 2 months.
Legal Regime of the Settlement of Disputes Arising from a Contract of Multimodal Carriage of Goods within CEMAC Land lock Countries
Authors: Chifu Gho Mary Soledad
Published: October 2024

CEMAC landlocked countries (specifically Chad and Central African Republic) depend solely on Cameroon who serves as a transit state for the transportation of goods to and from these landlocked countries. Thus, the entering into bilateral conventions helped to facilitate and create transit corridors for the transportation of goods amongst these countries. Meanwhile Cameroon which serves as a transit state to these landlocked countries has four modes of transport (road, rail, water and air), while Chad and Central African Republic have just two or three principal mode of transportation namely road, rail and air. However, these modes of transportation pose unique challenges, particularly in countries with limited infrastructure. Through doctrinal analysis of both primary and secondary sources of data, this article seeks to examine the legal framework in resolving disputes arising from contracts of multimodal carriage of goods available to landlocked countries of the Central African Economic and Monetary Community (CEMAC). Our findings revealed that, the legal framework in resolving disputes arising from contracts of multimodal carriage of goods available to landlocked countries are not effectively implemented. As a result, some salient recommendations have been made to bridge the gap between theory and practice amongst these countries in general and Cameroon in particular.
Legal Status of a Dead Person: A Critical Analysis in the Light of Jurisprudence
Authors: Hamid Syed Sarfaraj
Published: October 2024

This study states that while legal rules affecting the dead often have a practical aspect, one of the primary, and yet unrecognized, forces driving the creation of these legal rules are cultural norms, including dignity and respect for decedents’ wishes. In reaching this conclusion, this study adopts an interest theory approach to rights. Interest Theory recognizes persons currently incapable of making choices, such as the mentally incapacitated and infants, as potential right-holders. Using interest theory, this study argues that the dead, although unable to make real-time choices, are capable of being legal right-holders. Furthermore, certain interests, such as the interest in seeing one’s offspring survive or the interest in one’s reputation, can survive death. When these interests are protected by legal rules, the dead are granted de facto legal rights that can be enforced against the living. The law also strives to honor a decedent’s wishes and to protect his interests because society has chosen, within limits, to adhere to the principle of autonomy. This is why courts often consider a decedent’s wishes when determining the disposition of his corpse or property.
A UTILIZAÇÃO DOS MINI-IMPLANTES NO TRATAMENTO ORTODÔNTICO: UMA REVISÃO INTEGRATIVA DA LITERATURA
Authors: Oliveira Samuel , Almeida Patricia Karine Galvão Nunes de
Published: October 2024

Este artigo apresenta uma revisão integrativa da literatura sobre o uso de mini-implantes no tratamento ortodôntico, explorando suas indicações, vantagens, limitações e complicações. Foram selecionados 11 estudos publicados entre 2019 e 2024, a partir das bases de dados PubMed, LILACS, MEDLINE e BBO. A análise revelou que os mini-implantes desempenham um papel essencial na ancoragem ortodôntica, proporcionando maior controle na movimentação dentária e reduzindo a dependência de dispositivos extrabucais. Sua aplicação em tratamentos pré-protéticos e em casos de distalização e intrusão dentária mostrou resultados satisfatórios, com aumento na previsibilidade dos movimentos e diminuição no tempo total de tratamento. No entanto, o sucesso da técnica depende de fatores como a qualidade óssea do paciente, a correta inserção do mini-implante e o uso adequado da biomecânica ortodôntica. Além disso, complicações como perimucosite e a falha do implante podem ocorrer quando há má higienização ou sobrecarga inadequada. Os avanços tecnológicos, como o uso de guias cirúrgicos e softwares de planejamento tridimensional, são apontados como recursos importantes para minimizar riscos e melhorar os resultados clínicos. Conclui-se que os mini-implantes são uma ferramenta fundamental na ortodontia moderna, sendo crucial o aperfeiçoamento contínuo dos profissionais para maximizar seus benefícios e minimizar possíveis complicações.
Institutional environment of banking support for small business development in ukraine
Authors:   Scientific Research Institute of Armament and Military Equipment Testing and Certification, Zhezherun Yuliia
Published: October 2024

The article reveals the essence of the infrastructure structure that supports small businesses as an environment and the conditions for producing goods/services. The classification of the infrastructure of the support system for small and medium-sized businesses has been given. The small business support infrastructure components have been singled out: financial and credit, organizational and legal, informational and consulting, production and technical, social and environmental. Attention has been focused on the peculiarities of the functioning of infrastructure facilities supporting small businesses (business centers, business incubators, innovative business incubators, scientific and technological centers, technology transfer centers, small business support funds, leasing funds, consulting centers, other enterprises, institutions, and organizations) depending on the level of their function (state, regional, local). An analysis of small business support infrastructure facilities as of the end of 2023 was carried out. It has been found that the extensiveness of the infrastructure created by the state is used as one of the criteria for assessing the level of state support for the development of small businesses. It has been proposed to evaluate the innovative infrastructure of small business support of a separate region, considering the Digital Transformation Index, which includes the following sub-indices: institutional capacity, access to the internet, development of the Administrative Service Centers (TsNAPs), implementation of the paperless regime, digital education, the business card of the region, penetration of basic e-services, sectoral digital transformation. Keywords: small business, support infrastructure, infrastructure facility, innovative infrastructure, digital transformation.
Tools for the Portuguese contemporary art market
Authors: Duarte Adelaide
Published: October 2024

In the past two decades, the art market has seen significant growth, with scholars and academics across the globe showing newfound interest in its potential as an interdisciplinary field. This has led to a prolific number of publications, particularly through the lens of globalization. However, a dearth of studies from regions outside the main axes remains, despite the potential for such studies to challenge globalization. This article investigates the primary art market of Portugal, located in southwestern Europe, which borrows ideas from the Global South due to similarities with regions from outside Europe and North America. We apply this concept to the features from a country, namely Portugal that is considered semi-peripheral and marginalized within dominant narratives. We emphasize the permanent tension between the local actuation and the global aspirations of the players in this market. Using literature published on the subject, reports, and interviews, we systematize the mechanisms of activation of the primary market; the launch of art fairs; the emergence of contemporary art galleries, museums, and collectors; and the discourse surrounding the recognition of the global art scene. Despite being a small-scale, semi-peripheral market, a willingness exists to internationalize. Furthermore, in addition to its rich cultural history and substantial investments, mainly from the private sector, the market has attracted international audiences from the artistic milieu and thereby contributed to the heterogeneity observed in the Global South.
The role of artificial intelligence in higher medical education and the ethical challenges of its implementation
Authors: Perkins Mark , Pregowska Agnieszka
Published: October 2024

Artificial intelligence (AI) is penetrating higher medical education; however, its adoption remains low. A PRISMA-S search of the Web of Science database from 2020 to 2024, utilizing the search terms “artificial intelligence,” “medicine,” “education,” and “ethics,” reveals this trend. Four key areas of AI application in medical education are examined for their potential benefits: Educational support (such as personalized distance education), radiology (diagnostics), virtual reality (VR) (visualization and simulations), and generative text engines (GenText), such as ChatGPT (from the production of notes to syllabus design). However, significant ethical risks accompany AI adoption, and specific concerns are linked to each of these four areas. While AI is recognized as an important support tool in medical education, its slow integration hampers learning and diminishes student motivation, as evidenced by the challenges in implementing VR. In radiology, data-intensive training is hindered by poor connectivity, particularly affecting learners in developing countries. Ethical risks, such as bias in datasets (whether intentional or unintentional), need to be highlighted within educational programs. Students must be informed of the possible motivation behind the introduction of social and political bias in datasets, as well as the profit motive. Finally, the ethical risks accompanying the use of GenText are discussed, ranging from student reliance on instant text generation for assignments, which can hinder the development of critical thinking skills, to the potential danger of relying on AI-generated learning and treatment plans without sufficient human moderation.
Does improving diagnostic accuracy increase artificial intelligence adoption? A public acceptance survey using randomized scenarios of diagnostic methods
Authors: Hswen Yulin , Rafaï Ismaël , Lacombe Antoine , Davin-Casalena Bérengère , Dubois Dimitri , Blayac Thierry , Ventelou Bruno
Published: October 2024

This study examines the acceptance of artificial intelligence (AI)-based diagnostic alternatives compared to traditional biological testing through a randomized scenario experiment in the domain of neurodegenerative diseases (NDs). A total of 3225 pairwise choices of ND risk-prediction tools were offered to participants, with 1482 choices comparing AI with the biological saliva test and 1743 comparing AI+ with the saliva test (with AI+ using digital consumer data, in addition to electronic medical data). Overall, only 36.68% of responses showed preferences for AI/AI+ alternatives. Stratified by AI sensitivity levels, acceptance rates for AI/AI+ were 35.04% at 60% sensitivity and 31.63% at 70% sensitivity, and increased markedly to 48.68% at 95% sensitivity (p <0.01). Similarly, acceptance rates by specificity were 29.68%, 28.18%, and 44.24% at 60%, 70%, and 95% specificity, respectively (P < 0.01). Notably, AI consistently garnered higher acceptance rates (45.82%) than AI+ (28.92%) at comparable sensitivity and specificity levels, except at 60% sensitivity, where no significant difference was observed. These results highlight the nuanced preferences for AI diagnostics, with higher sensitivity and specificity significantly driving acceptance of AI diagnostics.
Evaluating the impact of brachytherapy duration on therapeutic outcomes in patients with cervical cancer
Authors: Han Haonan , Hou Hailing , Qiu Lin , Cheng Chingyun , Xu Keying , Kang Minglei , Chen Tingting , Yang Yanling , Li Xiangpan , Xu Liming
Published: October 2024

The total duration of radiotherapy for patients with cervical cancer should be limited to 56 days to optimize treatment outcomes. This study aimed to statistically evaluate the effects of extended radiotherapy duration on survival and complications in 649 patients with cervical cancer treated with brachytherapy at our institution from 2014 to 2019. All patients had undergone intensity-modulated external beam radiation therapy, with 525 receiving two-dimensional (2D) brachytherapy and 124 receiving three-dimensional (3D) brachytherapy. Using the inverse probability of treatment weighting (IPTW) and propensity score matching (PSM), clinical data regarding treatment duration, survival outcomes, and complications were analyzed. PSM revealed that overall survival (OS) did not significantly differ between patients receiving prolonged treatment (>56 days) and those receiving treatment for a standard duration (<56 days) (P > 0.05). However, among patients who had received 2D brachytherapy, prolonged treatment correlated with increased recurrence and metastasis risks (P < 0.001); this trend was not evident in patients receiving 3D brachytherapy (P = 0.287). Higher FIGO stages were associated with worse OS and higher progression risks, which persisted post-IPTW adjustment. Extended radiotherapy duration was linked to a higher incidence of rectal and bladder reactions, particularly in the 2D group. Consequently, strictly controlling radiotherapy duration for patients receiving 2D brachytherapy is essential to reduce recurrence and metastasis risks. Close monitoring of rectal and bladder reactions is also recommended.
Health expenditure and fiscal marksmanship before and during the coronavirus pandemic across the federal states of India
Authors: Jakovljevic Mihajlo , Monalisa Sahoo Pragyan , Sekhar Rout Himanshu
Published: October 2024

This study examined state-level health expenditure, fiscal marksmanship, and COVID-19 deaths among selected states in India. It (1) compared health expenditure between the pre-COVID-19 and the COVID-19 period in India and selected states; (2) investigated the fiscal marksmanship in the context of health expenditure at the national and state level; and (3) assessed the relationship between COVID-19 deaths, population density, health expenditure, and fiscal marksmanship. The study period from 2017 to 2021 was divided into pre-COVID-19 (2017-late – 2019) and COVID-19 (late-2019 – 2021). This study focused on India and selected Indian states, using data from state budget documents, Census 2011 for population density, and COVID-19 data from the government website. Descriptive statistics, percentages, ratios, graphs, and tools such as Theil’s U-Statistic and Pearson’s correlation were employed for analysis. Simple linear regression was used to analyze the impact of fiscal marksmanship and other variables on the case fatality ratio. This study revealed challenges in maintaining fiscal discipline during COVID-19, with disparities in capital expenditure among states. The results emphasized the need for increased health spending and structural changes to enhance resilience to future health crises, advocating for investments in infrastructure and services to improve preparedness.
Exploring innovative approaches to fundraising for palliative care
Authors: Shahriah Sunjida , Dwivedi Sachin , Amornmahaphun Sucheera , Seshkar Suman , Pouy Somaye , Puri Sidharth , Kaur Hemdeep , Mya Aye Shoon , Vernette N. Sangma Risa , Poh Teo Shyh
Published: October 2024

Palliative care is a holistic approach aimed at improving the quality of life for those facing life-limiting illnesses and their families. Palliative care services often face financial constraints that restrict their ability to reach all those in need. There are difficulties accessing traditional funding mechanisms; therefore, innovative fundraising strategies are required to sustain and expand palliative care initiatives. In this paper, diverse fundraising approaches for palliative care are described, based on group discussions and collective brainstorming sessions by clinicians undergoing a Fellowship in Palliative Care. Fundraising approaches that were deemed innovative, yet feasible to apply in each locality, were shortlisted and described, with their strengths and challenges outlined in detail. These approaches include art and photography exhibitions, “piggy-bank” projects, community-based fundraising, charity shops, lottery and lucky draws, shuttle bus services, grants from international organizations and collaborative networks, the use of tap-on technology, festive events, and restaurant partnerships. It is hoped that through these innovative approaches, collaborative efforts, strategic planning, and resource mobilization, it would be possible to generate funds to develop and provide palliative care services for those in need to fulfill a fundamental human right.
A cultural exposition model for interpreting architectural heritage: A study on Pingyao historical city
Authors: Liu Ming , Thimwatbunthong Sathit , Ungkawanichakul Piyanard
Published: October 2024

Architectural heritage, encompassing both its material and immaterial aspects, serves as a vital lens for understanding the historical, social, and esthetic values embedded in a society. As a reflection of cultural evolution, it offers insight into the architectural technologies, social structures, and collective memories of specific historical periods. This article investigates the architectural history of Pingyao historical city by employing theoretical perspectives that integrate material, social, and spiritual dimensions. The study demonstrates how the philosophy and cultural values of ancient Chinese society are reflected in the spatial and architectural forms of Pingyao. The material dimension considers how principles such as Feng Shui, numerology, and color symbolism shaped the city’s general layout and building designs. The social attribute addresses the influence of Confucianism on spatial organization, the use of culturally significant architectural elements, and the function of key structures in fostering social unity among the population. The spiritual aspect explores concepts of Eastern origin, such as Yin and Yang, the Five Elements theory, and the “Unity of Heaven and Humanity,” as these are incorporated into the city’s external architecture. Furthermore, it examines the influence of Buddhism and Daoism on Pyingyao’s architectural features. This comprehensive analysis reveals that Pingyao is far more than a collection of historic buildings; it is an intricate cultural artifact, offering a unique perspective on earlier stages of Chinese thought and society. Therefore, the preservation and study of Pingyao’s architecture offer a valuable opportunity to deepen our understanding of China’s architectural history.
Bioinformatics approach to identifying potential cancer-associated mutations in CCL2
Authors: Kamal Shah , Ullah Najeeb , Amanullah Amanullah , Mujtaba Mariam Ahmed , Khan Kashif Ali , Deng Cheng , Lai Shanshan , Kamal Mohammad Amjad
Published: October 2024

Chemokine C-C motif ligand 2 (CCL2), also known as monocyte chemoattractant protein 1 or small inducible cytokine A2, is a cytokine from the CC chemokine family. It plays a crucial role in recruiting monocytes, memory T-cells, and dendritic cells to inflammatory sites resulting from tissue injury or infection. C-C motif chemokine receptor 2 (CCR2) is a chemokine receptor that may influence lymphocyte function. The interaction between CCL2 and CCR2 is essential for inflammatory responses and cancer regulation, as it attracts monocytes and macrophages to tumor sites, facilitating tumor growth and metastasis. Given the importance of CCL2 in regulating cell trafficking and cancer progression, we employed a bioinformatics approach to examine the effects of oncogenic missense mutations in CCL2 on CCR2 activation. We used precise computational methods to identify the molecular characteristics responsible for the altered activity and interactions, thereby enhancing our understanding of the molecular mechanisms underlying disease progression. We generated a three-dimensional model of the CCL2 protein with the identified mutations using the I-TASSER algorithm. The effects of these mutations on the protein’s stability and functional properties were evaluated using various prediction tools, and molecular dynamics simulations were conducted using WebGro software. Our analysis of 83 CCL2 missense mutations identified 10 disease-causing mutations, including C59G, which was directly linked to cancer. The C59G mutation increases the binding interaction between CCL2 and CCR2. The C59G position was determined to be highly conserved, and substitutions of cysteine (C) 59 with glycine (G) altered CCL2 activity. Our results suggest that this mutation alters the CCL2–CCR2 binding activity, lowering the risk of developing cancer and defending against pathogen invasion during the neutrophil-mediated innate immune response.
Internet of things as a tool for ensuring material security of Military Units and Institutions
Authors: Pawlisiak Mieczysław , Maslii Oleh
Published: October 2024

Abstract: Material security of military units and institutions is one of the determinants of the ability to carry out combat tasks. It will be possible to provide it, among other Things, by obtaining information on the existing material needs and the possibility of meeting them. This information can be obtained through the use of technologically advanced technologies such as the Internet of Things. The aim of the article is to publish the results of research indicating whether and to what extent the Internet of Things will determine the logistical security of military units and institutions. In order to achieve this goal, a general research problem has been identified in the form of a question: "How will the Internet of Things affect the acquisition of information necessary to make decisions regarding the satisfaction of the material needs of military units and institutions"? The solution to the general research problem was achieved by refining it with four specific research problems. Theoretical methods (analysis, synthesis) supplemented by an empirical method – participant observation – were used to solve them. An important item in the research process were the results of surveys conducted with persons performing tasks related to ensuring material security in military units and institutions. The results obtained in the course of the research clearly indicate the importance of information for decision-making related to meeting the material needs of military units and institutions. On the other hand, the ability to provide material resources will depend not only on the resources at hand, but mainly on the time of obtaining information on the occurrence of needs in a specific place and time. This requirement can be met through the use of modern technologies such as the Internet of Things. In addition to the undoubted benefits, the results of the study also pointed to the possibility of threats during the use of the Internet of Things. Therefore, it is necessary to balance the benefits and threats and make a decision on the possibility of implementing the Internet of Things for solutions supporting the implementation of material security tasks for military units and institutions.
Data is the fuel of generative artificial intelligence
Authors: Sokołowski Wojciech , Ficoń Krzysztof , Florczyk-Żółtowska Marzena
Published: October 2024

TThe aim of the article is to present the generative technology of artificial intelligence and a general analysis of its achievements and technological limitations. In turn, the hypothesis is as follows: data is the main factor ensuring the development of generative AI. The identified research niche includes stimulants of this development, the need to clarify the concept of generative AI and the indication of the most frequently used sources and methods of obtaining data. At the beginning, the concept and genesis of artificial intelligence were explained, which was necessary to move on to further considerations regarding the analyzed generative artificial intelligence. The self-learning mechanisms used by this type of artificial intelligence are discussed, consisting mainly in the analysis of specific data sets, thanks to which computers learn things that have not been known before. The advantages of generative artificial intelligence were also indicated, including increased productivity, greater efficiency and high creativity. Part of the attention was also paid to the limitations of this technology, including inaccurate and fuzzy output information, uncritical analyzes and often biased conclusions, copyright infringement and high requirements for memory and computing power of computers. Two factors have been identified that have recently stimulated the development of generative intelligence, i.e. the growing computing power of computers and easy access to large data sets. The main subject of considerations are large data sets, dynamically and uncontrollably self-replicating in Internet servers. Today, data resources are collected very efficiently, including: in Big Data, Cloud Computing and Internet of Things technologies, and their use is almost cost-free and publicly available. It was enough to improve the technology of artificial neural networks, expand multi-layer machine learning and create deep learning for generative intelligence to gain enormous momentum and become a symbol of the beginning of the 21st century. The whole investigation was summarized with a synthetic ending.
Pengaruh Kompensasi Dan Lingkungan Kerja Terhadap Kinerja Pegawai Dinas Perkimtan Kota Palembang Dengan Lingkungan Kerja Sebagai Variabel Intervening
Authors: Muhammad Hendri Mulyadi  , Djatmiko Noviantoro  , Yusro Hakimah
Published: October 2024

This study aims to test and prove the effect of compensation and work environment on the performance of employees of the Palembang City Perkimtan Service, both directly and indirectly, with work motivation as an intervening variable. The population in this study were all employees of the Palembang City Perkimtan Service, totaling 82 people. The sampling technique used the saturated sample method, so that the entire population was used as a research sample. Thus, the number of samples used was 82 employees. The data were analyzed using the Structural Equation Model (SEM) method operated through the Partial Least Square (PLS) program. The results of the study indicate that compensation variables affect work motivation, work environment variables affect work motivation, compensation variables affect performance, work environment variables affect performance, and work motivation variables affect performance. In addition, compensation variables also affect performance with work motivation as an intervening variable, and work environment variables affect performance with work motivation as an intervening variable.
Hydrogen-bonded macrocycle-mediated dimerization for orthogonal supramolecular polymerization
Authors: Yu Wentao , Yang Zhiyao , Yu Chengkan , Li Xiaowei , Yuan Lihua
Published: October 2024

Orthogonal self-assembly represents a useful methodology to construct supramolecular polymers with AA and AB type monomers as commonly used for covalent bond-linked polymers. So far, the design of such monomers has relied heavily on three-dimensional macrocycles and the use of two-dimensional shape-persistent macrocycle for this purpose remains rather rare. Here, we demonstrate a dimerization motif based on a hydrogen-bonded macrocycle that can be effectively applied to form orthogonal supramolecular polymers. The macrocycle-mediated connectivity was confirmed by single crystal X-ray diﬀraction, which reveals a unique 2:2 binding motif between host and guest bridged by two cationic pyridinum end groups through π-stacking interactions and other cooperative intermolecular forces. Zinc ion-induced coordination with the macrocycle and a terpyridinium derivative enables orthogonal polymerization as revealed by 1H NMR, DLS, and TEM techniques. In addition, viscosity measurements show a transition from oligomers to polymers at the critical polymerization concentration of 17 mM. These polymers are highly concentration dependent. Establishing this new dimerization motif with shape-persistent H-bonded macrocycle widens the scope of options of non-covalent building blocks for supramolecular polymers and augurs well for the future development of functional materials.
Impacto de la Corrupción sobre la Inversión Extranjera Directa en el Ecuador
Authors: Litardo Chavez Nahomi Alexandra , Hernández Amaya Kimberly Katherine , Flores González Denys Antonio
Published: October 2024

En un contexto global cada vez más interconectado, la inversión extranjera directa se ha convertido en un componente crucial para el desarrollo económico de los países en vías de desarrollo. Sin embargo, factores como la corrupción pueden influir significativamente en la capacidad de un país para atraer este tipo de inversión, afectando su crecimiento económico y estabilidad. El objetivo principal de la investigación es analizar el impacto de la corrupción en la inversión extranjera directa, identificando los factores económicos y sociales que mediatizan esta relación. La metodología empleada combina análisis cuantitativo y cualitativo a través de un modelo econométrico, utilizando datos de series temporales de fuentes secundarias como el Banco Central del Ecuador y el Banco Mundial, abarcando el período de 2000 a 2022. Los resultados del análisis revelan que la corrupción tiene un efecto significativamente negativo en la inversión extranjera directa, sugiriendo que un incremento en los niveles de corrupción puede disuadir a los inversores extranjeros. En conclusión, el estudio subraya la necesidad imperiosa de mejorar la percepción de la corrupción y fortalecer las instituciones ecuatorianas para crear un entorno más atractivo y estable que incentive la inversión extranjera en el país. Estas medidas podrían contribuir a un desarrollo económico más robusto y sostenible en Ecuador.
Classification of Corn Diseases and Pests Using Fuzzy Naïve Bayes Method
Authors: Resti Yulia , A. Zayanti Des , R. Dewi Novi , Yani Irsyadi , Darmawan Fauzi , Jimmy
Published: October 2024

Corn is an essential dietary source for humans and animals. In addition to being a food source, corn has numerous benefits as a manufacturing commodity. The quality of grain crops must be considered to minimise the likelihood of disease and pest infestations. Therefore, the diseases and pests that attack corn plants must be classified so that farmers can control them during the growth period of corn plants. The fuzzy naive Bayes method is a statistical machine learning method that can be used to classify the diseases and pests of corn crops based on colour space-transformed digital images. This study aims to classify corn plant diseases and pests using the fuzzy naive Bayes method. Digital images of corn plant diseases and pests were transformed into a red, green and blue colour space model. The following seven classes of corn plant diseases and pests were classified: leaf rust disease, downy mildew disease, leaf blight disease, Locusta pest, Heliotis armigera pest, Spodoptera frugiperdita pest and non-pathogenic pest. With this method, the classification model achieves an accuracy of 87.83%, a macro precision of 34.91%, a macro recall of 35.90% and a macro f-score of 33.82%.
Enhancing Students' Development through Human-Space Correlation: A Conceptual Review of Co-Working Spaces in Educational Institutions
Authors: Mohamad Noraiham , Wan Ahmad Kamil Wan Sofiya , Mohamad Juoi Jariah , Kamat Seri Rahayu , Selamat Siti Rahayu , Abdul Hamid Rahimah , Anang Masuri Mohd Rayme
Published: October 2024

Education spaces are an important factor in maximising students' learning experience. Tertiary education institutions in Malaysia could benefit from co-working spaces as informal learning spaces to improve student interactions, well-being, productivity, and knowledge. This paper aims to establish a framework for developing co-working spaces in tertiary education institutions, particularly in Malaysian institutions. This research undertakes a review of journal articles, reports, and other documents gathered from the Google Scholar database concerning two main areas: firstly, co-working spaces, and secondly, education institutions. The data was analysed using VOSviewer software for specific keywords; 'education institution', 'university', 'student', and 'library'. The review brings forth important attributes when developing co-working spaces in tertiary education institutions. The findings can tremendously help education institutions apply the concept of co-working spaces to enhance learning environments for students' holistic development
Predicting Mental Health Outcomes Using Wearable Device Data and Machine Learning
Authors: Sanjay Suryawanshi Nikhil
Published: October 2024

This paper proposes a machine learning- based system designed to predict mental health outcomes using wearable device data. The system is conceptualized to process physiological and behavioral data such as heart rate, sleep patterns, and activity levels collected from wearable technology. Key stages of the system include data preprocessing, feature extraction, and model training using multiple machine-learning algorithms, including Random Forest, Support Vector Machine, XGBoost, and Logistic Regression. These models are combined using a voting-based ensemble classifier to improve prediction accuracy. While the system has not yet been implemented, expected results suggest that this approach will enhance prediction reliability and offer real-time insights into mental health conditions. The proposed system is envisioned to facilitate early detection of mental health disorders, thereby aiding in timely interventions and personalized care.
AI in Healthcare: Bridging the Gap between Research and Clinical Implementation
Authors: Lanka Srinivas , Madala Pavithra
Published: October 2024

Artificial intelligence (AI) has the potential to revolutionize healthcare by enhancing diagnostic accuracy, reducing administrative burdens, and providing personalized treatment. However, the slow adoption of AI in healthcare is due to obstacles associated with ethical considerations, data management, regulations, and technological capabilities. The results of our study highlight specific challenges related to ethics, technology, regulatory, social, economic, and workforce barriers that affect the implementation of AI in healthcare. We aim to improve current knowledge by providing a more comprehensive understanding, by bridging the gap, and addressing the barriers to implement AI in the healthcare sector.
A New Era of Tooth Preparation and Gingitage Retraction Technique: A Case Report
Authors: Verma Diksha , Kumar M.V Sunil , Kumar Rajesh , Kumar Krishan , Utwal Simran
Published: October 2024

The demand for procedures intended to improve dental aesthetics has increased recently. Preserving the teeth and surrounding soft structures to the greatest extent possible is preferred in this situation by both patients and dentists. When using fixed prostheses, maintaining the stability and health of soft tissues is a constant struggle. Bone tissue health and soft tissue health are directly correlated. The long-term efficacy of prosthetic therapy thus depends on preserving tissue health and being free of mucositis. This case report describes the successful application of the gingitage technique in a patient requiring aesthetic enhancement of the gingival margins surrounding dental restorations. The patient presented with uneven gingival contours and mild inflammation around subgingival margins of existing restorations, compromising both function and aesthetics. Results demonstrated significant improvements in gingival health, a more balanced gingival margin, and an enhanced aesthetic outcome. Follow-up assessments revealed stable gingival contours and an overall increase in patient satisfaction. This case report underscores the effectiveness of the gingitage technique as a minimally invasive solution for enhancing soft tissue aesthetics and supporting the longevity of dental restorations.