bluuebunny/crossref_metadata_2025 huggingface dataset:
MECHANISTIC DEHUMANIZATION IN ALDOUS HUXLEY’S BRAVE NEW WORLD
Authors: Ivana Ivana , Sari Dian Eka
Published: September 2022

ABSTRACT

Knowledge advancement in the field of technology is often considered an advantage. Humans are living alongside the disadvantages. Dependency ontechnological inventions has brought humans to a threshold where technology goes beyond humanity. This occurrence thus possibly leads todehumanization. Two problems are proposed in this research: forms of mechanistic dehumanization and bad impacts of mechanistic dehumanization. The forms of mechanistic dehumanization focus on acts of human degradation while the bad impacts of mechanistic dehumanization focus on the human that represents machine and robot. Michel Foucault’s sociological theory is applied to reveal the problems proposed in this research. Two of Foucault’s concepts are considered appropriate to be utilized: Power and Knowledge and the Regime of Truth. Both concepts emphasize the practice of power imposed on the powerless and theacceptance by the powerless. The finding discloses that one who poses power and knowledge can produce laws that are imposed toward thepowerless and shape them as the powerful wish to obtain the benefit. The powerless ought to be submissive, obedient even accept the truth of lawsunconsciously. People in Aldous Huxley’s Brave New World show their unconscious acceptance of the Controller’s laws therefore they are treated and degraded as low as commodities to be made use of by the Controller. They become cold and rigid thus they show no distinction between humans and machines.
ASSISTED SUICIDE IN JOJO MOYES’ ME BEFORE YOU
Authors: Lestari Ria
Published: September 2022

ABSTRACT This research aims to analyze Assisted Suicide that is portrayed in a novel entitled Me Before You by Jojo Moyes. It tells about the male main character, Traynor, who chooses to end his life through assisted suicide because he is paralyzed as a result of a motorcycle accident. There are two questions to discuss in this research; the causes of assisted suicide and the causes of objectification. This research uses existentialism theory by JeanPaul Sartre.There are some concepts of theory i.e Freedom, The look, and The body that help this research to describe the causes of assisted suicide and the causes of objectification. The research method used by the writer was the qualitative research method. The result of this research showed that the cause of assisted suicide is the excessive freedom to choose to be free from physical pain and emotional pain. Then, the cause of objectification is the existence of the Other, such as The Look and The body that affect Traynor’s existence when people around him try to change his mind not to commit suicide.
SCHIZOPHRENIFORM IN ANDRES HEINZ’S BLACK SWAN
Authors: Zarlina Juni
Published: September 2022

Abstract

This research aims to analyze the personality disorder, Schizophreniform, that happened in this drama, Black Swan by Andres Heinz. It describes that the maincharacter, Nina Sayers, has a psychological problem. She suffers from Schizophreniform. Three questions appear to discuss i.e. the causes, the symptoms, and defense mechanism of Schizophreniform perceived by Nina Sayers the main character. This research uses a theory of Psychoanalysis by Sigmund Freud. There are two concepts to be applied to three problems in this research. The concepts are Id, Ego & Superego, and Defense Mechanism. These concepts help this research to describe the symptoms and the defense mechanism of Schizophreniform. The result of this research found that Nina Sayers shows the symptoms of Schizophreniform after experiencing the stressful event to be a new swan queen in the prestigious ballet company and poor social interaction as the causes of Schizophreniform. The symptoms are visual hallucinations and delusions. Then, the Defense Mechanisms of Schizophreniform that appear in this drama are identifications and Introjections.
HUMORS RELATED TO CULINARY LABELS IN INSTAGRAM
Authors: Aprila Natasha
Published: September 2022

Abstract

The research was aimed to analyze the functions and types of humor Indonesian culinary entrepreneurs tend to use in writing their culinary labels. Humor onwriting and pronunciation of culinary labels is very easy to remember and will  arise the curiosity of anyone who reads the culinary labels and wants to try themenu for sale in a culinary place. Therefore, this research analyzed the humor contained in the culinary labels on Instagram because nowadays some peopleuse social media as a means of promoting their business. Based on the research objectives above, the writer used qualitative research methods to collect andanalyze data. In this study, the writer found three functions of humor, which are humor to entertain, humor to criticize or ridicule, and humor to convey popularthings. Based on these findings, the writer concludes that the function of humor to entertain is one of the functions of humor that is often used in writing culinary labels. The writer hopes that the readers can develop the language by using humor language to develop linguistic language and also to improve the culinary business.
Values Lost in Society in the Eyes of Academics
Authors: KOÇ Sevgi , YAYLA Ahmet
Published: September 2022

Although there are numerous studies and discussions about the concept of value, it is claimed to lack an objective basis. The concept of value is difficult to define from a single perspective because it relates to many disciplines, especially the social sciences. Philosophy, sociology, psychology, religious sciences, anthropology, and historical sciences have attributed different meanings to the concept of value. However, the fact that the concept of value is related to human behavior has been a common point in all disciplines of social sciences. Values are essential in terms of social sciences because they interpret human behavior (Ulusoy & Dilmaç, 2016). Therefore, this study aimed to determine what academics thought about the core values lost in society and what kind of solutions they offered to that problem. The sample consisted of 16 academics from Van Yuzuncu Yıl University/Turkey. The sample consisted of 12 men and 4 women. The study adopted a qualitative research design. Data were collected using a semi-structured interview questionnaire consisting of open-ended questions. The data were analyzed using descriptive analysis. The findings focused on participants’ views of the concept of values, the values lost in society, values problems, and solutions to the lost values.
Modernising the UK Constitution - Draft Legislation
Authors: McBain Graham
Published: September 2022

Modernising the UK Constitution - Draft Legislation.
Información Editorial y Equipo de Artilugio #8
Authors: Editorial Comité
Published: September 2022

Información Editorial y Equipo de Artilugio #8, 2022: "Prácticas artísticas, crisis planetaria y vidas posibles"
Activismo artístico y crisis planetaria. Resistencia y communitas del dolor en los discursos de ContraArte
Authors: Delupi Baal
Published: September 2022

El presente artículo tiene como objetivo analizar las construcciones sociodiscursivas del grupo de activismo artístico ContraArte, gestado en la ciudad de Córdoba hace trece años. Específicamente, nos interrogamos por las acciones llevadas adelante en el periodo 2021 en contra de la empresa Porta Hnos. que ha producido contaminación en la zona sur de la ciudad, dejando a cientos de familias con distintos tipos de secuelas.

En primer término, introducimos al lector en la importancia que tienen las acciones artístico-políticas a favor del medioambiente, para luego caracterizar los derroteros del grupo ContraArte. En segundo lugar, expondremos el prisma teórico que opera como punto de partida, seguido por el análisis de las fotografías de la red social Facebook que muestra la intervención muralista que el grupo lleva adelante en el barrio San Antonio. Los resultados de investigación revelan la construcción de un cronotopo de resistencia y disidencia a favor del medio ambiente que configura una communitas del dolor (siempre marginal) al interior del discurso social argentino.
Ensayo fotográfico: El retorno del agua…
Authors: Ceniceros Ortiz Brenda Isela
Published: September 2022

Este ensayo fotográfico fue realizado a través de recorridos etnográficos por las acequias. En él se reflexiona acerca del río, un río fronterizo llamado río Bravo/Grande que alguna vez fue bravo y hoy se surca como una herida en el desierto chihuahuense. Al caminar se documenta, mediante registros fotográficos y escritos en un diario de campo, y reflexiona a partir de capturas de los elementos naturales y del paisaje, del contraste entre lo natural y lo artifiial, las ruinas y las reminiscencias.
2029: una pieza sonora de sonic fiction en el contexto postpandemia en Lima, Perú
Authors: Beaumont Lucía
Published: September 2022

Después de dos años de pandemia, nuestra relación con el entorno y la tecnología ha cambiado. Las rutinas han variado y, por lo tanto, nuestra percepción e imaginarios también. Cómo nos imaginamos la nueva normalidad y el futuro que nos depara se modifica. El proyecto sonoro se denomina 2029 y consiste en plantear una ficción a partir de sonidos cotidianos del entorno, desde mi subjetividad y percepción, y manipularlos para crear una narrativa de una posibilidad de futuro. Se trata de un proyecto sonoro de ciencia ficción que busca hacer reflexionar sobre el contexto actual en el país y la sensación incómoda de incertidumbre por la que estamos pasando.
Nota editorial #8: Prácticas artísticas, crisis planetaria y vidas posibles
Authors: Yaya Marcela , Martín Daniela
Published: September 2022

Desde múltiples aspectos, la pandemia global que tuvo comienzo en el año 2020 nos puso en jaque como sociedad. Este fenómeno sanitario (también social, político, ecológico) tuvo su continuidad en el año 2021, y todavía no hemos podido superarlo. Sus múltiples consecuencias han generado una trama compleja que provoca situaciones críticas tanto en nuestras vidas individuales como colectivas y planetarias. Es por esto que para el número 8° de la Revista Artilugio, consideramos necesario proponer como eje temático “Prácticas artísticas, crisis planetaria y vidas posibles”. Afirmando estas crisis que nos atraviesan, urge la tarea de imaginar otras formas de vida, otras proposiciones vitales que nos permitan diseñar y crear modos posibles de existencia que no se vinculen –como pareciera ser– a la catástrofe y a la destrucción como únicos destinos posibles. Son muchas las narrativas que construyen el fin de la humanidad, el fracaso del planeta, el exterminio y la desolación. Es, quizás, ese panorama desalentador y despotenciador, el que hace evidente la necesidad de narrativas que nos conecten con la vida, con lo que aún crece y se multiplica, con los movimientos deseantes y transformadores.

Así, encontramos en la imaginación artística, la sensibilidad comunitaria, el cuidado y la producción de vida, claves fundamentales para transitar estos momentos álgidos de crisis planetaria. Nos preguntamos, entonces, ¿qué propuestas vitales hacemos desde nuestras prácticas artísticas para imaginar otros mundos posibles?, ¿qué saberes ponemos en juego, qué diálogos generamos, qué existencias proponemos como alternativas?, ¿cómo pensamos las artes desde esta perspectiva?
Ensayo, error y reconfiguración. El trabajo creativo emergente durante la pandemia en la Ciudad de México
Authors: Molina Roldán Ahtziri Eréndira , Garduño Bello Bianca
Published: September 2022

El presente texto revisa las formas emergentes que las personas que trabajan en el sector económico del trabajo creativo han puesto en práctica para generar recursos de subsistencia a lo largo de dos años de pandemia. Las autoras proponemos que algunos modos de trabajo resultantes de la necesidad de mantener distanciamiento social trascendieron la emergencia y forman parte de la cotidianidad, especialmente los vinculados con las tecnologías de la comunicación y la información. Mediante el análisis cualitativo de entrevistas, datos cuantitativos de consulta pública y revisión de trabajos de investigación sobre el tema identificamos que los momentos de las diferentes medidas sanitarias fueron marcando el ritmo de los cambios, ajustes e innovaciones del trabajo creativo en el Área Metropolitana de la Ciudad de México. Un sector que pese a sus esfuerzos por generar nuevas formas de interacción, producción y difusión de su labor creativa desde el inicio de la pandemia, enfrenta la agudización de las condiciones de precariedad laboral en una reconfiguración que favorece la desigualdad en el acceso a recursos y oportunidades para el desarrollo de su vida profesional como consecuencia de la crisis.
La lucha por el agua en Mendoza. Una lectura desde la performance
Authors: Sarale Marina Laura
Published: September 2022

El presente trabajo analiza desde el punto de vista de la performance dos eventos acontecidos en Mendoza durante la lucha por la defensa del agua y en contra de la megaminería contaminante. Tanto la Marcha más grande de la historia como la Marcha de los tambores por el agua presentan características singulares que las distinguen de otras manifestaciones porque en su desarrollo alcanzan el estatuto de performance artística. Tales características son analizadas a partir de estructuras y convenciones particulares presentes en cada una. Además, observamos cómo opera en ambos eventos la multimedialidad en lo que se conoce como constelaciones de performance. Finalmente, realizamos una breve reflexión comparativa sobre una obra de teatro inspirada en las manifestaciones de diciembre desde el punto de vista del archivo y el repertorio.
Diálogos #8: Prácticas artísticas, crisis planetaria y vidas posibles
Authors: Biset Emmanuel , Bornancini Belén , Moyano Cortéz Nehuén , Triquell Agustina
Published: September 2022

En esta edición de la Revista Artilugio, nuestrxs invitadxs1 a la sección Diálogos comparten sus experiencias y despliegan un conjunto de preguntas alrededor del eje temático “Prácticas artísticas, crisis planetaria y vidas posibles”. A lo largo de la conversación delinean cuestiones sobre las formas de habitabilidad, enlazando sus prácticas vitales con las profesionales. De este modo van emergiendo las diversas problemáticas vinculadas al tema: la noción de territorio como recurso económico, las prácticas predatorias, los múltiples modos de humanización de los ambientes naturales en los procesos de migración desde los núcleos urbanos hacia lugares menos habitados, los ciclos reiterados de incendios forestales y la construcción de grandes autovías en áreas protegidas. Al mismo tiempo perciben que ni la mirada conservacionista ni la ecológica alcanzan a dimensionar la urgencia de esta enorme crisis. Resultan necesarias otras “figuras del pensamiento” que habiliten la crítica para “hacer vacilar las certezas e imaginar un mundo posible”. En este punto, todxs acuerdan que las prácticas artísticas tienen ese potencial; son capaces de proyectar acciones “sin un saber asignado de antemano”.  En el debate, aparece la idea de un “común” que presienten posible a partir de la construcción de alianzas. Una comunidad (nunca exenta de problemas) que no se limite a lo humano, que abarque a otros seres ya sean vivos o inertes a participar de ella. Así, quedan flotando en el aire las preguntas que nuestrxs invitadxs compartieron: ¿es “lo común” una forma de habitabilidad posible?, ¿o tal vez sea lo “in-común”, es decir, aquello radicalmente in-apropiable?, ¿se encontrarán allí las formas de atravesar el umbral entre lo humano y lo no-humano? ___ Dialogantes invitadxs: Emmanuel Biset, Belén Bornancini, Nehuén Moyano Cortéz y Agustina Triquell Coordinación general: Carolina Cismondi y Constanza Molina Dirección: Juan Tello Contenido: Constanza Molina y Hernando Varela Asistencia de producción: María Sol Rassi Sonido directo: Pablo Dagassan Iluminación y coordinación técnica: Pablo Dagassan Cámaras: Vanina Gottardi, Juan Tello, Marcela Yaya Edición y postproducción de imagen: Vanina Gottardi Grafismo y animación: Sebastián Cáceres Gráfica: Marina Fernández Música, edición de sonido y pos-sonido: Federico Ragessi __ [1] Optamos por el empleo de la “x” para evitar el uso genérico del masculino en aras de seguir produciendo reflexiones en un lenguaje inclusivo, no sexista.
«Geografías turísticas»: moda y modos de viajar en la España de la primera mitad del siglo xx
Authors: Gil de Arriba Carmen
Published: September 2022

La actividad turística en España experimenta un proceso significativo de renovación durante la primera mitad del siglo xx. En este periodo se forman unas iniciales «geografías turísticas» relacionadas con la mejora de las infraestructuras de transporte y de los medios de acceso. El incremento de la movilidad y de las posibilidades de desplazamiento influyó en las primeras iniciativas de planificación turística a escala española, lo que resultó determinante en la conformación de las rutas e itinerarios turísticos modernos, previos al turismo de masas.
Exilio y represión científica en el primer franquismo: el caso de Enrique Moles
Authors: Sales Joaquim , Nieto-Galan Agustí
Published: September 2022

La revisión de la biografía del químico Enrique Moles Ormella (1883-1953), y, en particular, de sus procesos judiciales en el primer franquismo, aporta nuevos elementos de reflexión con relación a las tipologías del exilio español de la Guerra Civil, así como con el papel de los científicos durante el periodo bélico y los inmediatos años posteriores. Las vicisitudes de Moles en la Dictadura de Primo de Rivera, la República, la Guerra Civil y en la Dictadura de Franco demuestran la compleja interrelación entre ciencia e ideología, que debe ser analizada en su contexto histórico, más allá de distinciones esencialistas, a veces demasiado simplistas, entre ciencia y poder.
Efficacy of workstation exercise and ergonomic exercise on nursing staff – a randomized clinical trial
Authors: Patil Deepali
Published: September 2022

The nurses’ population comprises of almost majority of the health care staff in the hospitals and other clinical settings. This population was undermined in the past but in recent years, many studies have been focused on this group to increase efficacy along with analyzing and reducing adjoining risks. The illness most frequent for absenteeism and quality of work hampering is back pain. Hence, this study targets the interventions for low back pain in the nurses. The participants (n=120) will be selected from the hospital setting and divided into 3 random groups. Group A will perform work station exercises, group B will undergo ergonomic changes and advices and group C will be the control group. Each group will have 40 participants each and the participants will implement the interventions of the allotted protocol for 2 months. The initial and final changes will be noted as day 1 and day 60. The outcome measures used will be Visual Analog Scale for pain rating and WHO Quality of Life scale (BREF) for ratings in the standard and quality of living. In post intervention, the exercise modification group performed better than the ergonomic advice group. The VAS and the QOL grading showed a significant change. The control group had a non-significant change. This study concluded that both the workplace exercises and the ergonomic advices show a positive impact on low back pain in the nurses. The workplace exercises are although more efficient than the ergonomic advices.
Association of poor sleep with low back pain among symptomatic and asymptomatic population
Authors: Phansopkar Pratik
Published: September 2022

Although Low back pain puts an immerse economic strain on healthcare services, this disease is responsible for impacting people’s daily lives. Sleep quality has gained interest for people with musculoskeletal pain conditions as a contributing factor to the outcome. Sleep consistency has created consideration as a risk factor to the outcomes for people with MSK pain disorders. According to several studies, there is a bidirectional relationship between pain severity and sleep quality. The recent focus on the interaction of inflammatory processes in pain and sleep, on the one hand, leads to neuro-immunological pathways that may contribute to the close relationship between pain and sleep, on the other. To study association of poor sleep with low back pain among symptomatic and asymptomatic population. All asymptomatic and symptomatic individuals with low back pain in the group between 35-50 years of age filled the survey using Visual Analogue Scale (VAS) and Insomnia Severity Index Questionnaire, and the data was analyzed. There's a link between low back pain and a lack of sleep. When compared to asymptomatic individuals, the visual analogue score for pain and the insomnia severity index score were higher in the symptomatic low back pain population, implying a bidirectional relationship between low back pain and poor sleep. In thisstudy, we discovered a link between poorsleep and low back discomfort. Thisresearch found that there is a bidirectional relationship between low back discomfort and poor sleep, with one affecting the other and vice versa
Newcastle disease virus in poultry animals
Authors: Gupta Amit
Published: September 2022

Newcastle disease virus (family Paramyxoviridae; genus Avulavirus), poultry disease isextensively spread in Asia, Africa, USA and Canada. In literature, strains of Newcastle disease virus are worldwide reported and causing a huge loss to the poultry industries. The present review discusses about Newcastle disease virus and mentioning about its clinical trial-based studies and also discussed about surveillance-based studies and vaccination. In this literature there should be more focus area on the techniques to make a vaccination successful and make any permanent cure for it. Also, we have checked the mortality rate of different states so that we should perform our techniques in those countries. In addition, this literature includes bioinformatics approach study various strains of Newcastle disease virus
Method development and validation of spray content uniformity for ipratropium bromide and budesonide in nasal spray
Authors: shah Abhay
Published: September 2022

Ipratropium bromide and Budesonide is combined Pharmaceutical Nasal dosage form. The label claim of this combined dosage form is 21 mcg of Ipratropium Bromide and64 mcg of Budesonide per Spray. It is for treatment of allergic rhinitis. Spray content uniformity is in-vitro investigational test which provides idea of uniformity of product throughout product life cycle. The present study aimed to validate High Performance Liquid Chromatography method for determination of spray content uniformity of these analytes. This validation study performed as per guidelines of International Conference on Harmonization and covers Precision, Linearity, Accuracy, Robustness, Ruggedness, stability of analytical solution and Specificity. The reversed phase chromatographic method uses a mobile phase prepared by mixing Buffer containing Sodium dihydrogen orthophosphate with Acetonitrile, Zorb ax CN150 mm column, 1.5 ml per min flow rate, 220 nm wavelength, 25°C column oven and 50 μL injection volume. The method found linear over the range of 50% to 150% of target concentration with correlation coefficient of 0.9997 for Ipratropium bromide and 0.9999 for Budesonide. The recoveries obtained were 103.1% - 103.8% for Ipratropium bromide and 97.0% - 100.1% for Budesonide. %Related Standard Deviation found well within the acceptance criteria for precision. No interference found at the retention time of analyte peaks in blank, placebo and degradation conditions describe specificity of method. The method showed a successful application for determination of Ipratropium bromide and Budesonide in Nasal spray pharmaceutical formulation.
Impact of covid-19 on mediocre life-style and their psychology (Special emphasis on middle-class indian households)
Authors: Agggarwal Shipra
Published: September 2022

India being the second most populated nation, observed the chronic outbreak of Novel Coronavirus as an instrumental factor for bringing about a major shift in the conduct of routine work and regular course of common life during the tragic year of 2020. The virus has given severe jolts to the economy, its distinct classes as well as its citizens alike, projecting far reaching effects across the country and disrupting the ordinary flow of the vital world. With special reference to the middle- class households in India, the purpose of this study is to highlight the impact of COVID-19 on the various facets of mediocre lifestyle including law and order, family and festivals, income and expenditure, mental and physical health, community welfare and social work, creativity and culture, citizen compliance and environmental concern etc. This research intends to provide a useful insight on how the virus is affecting the perspective of mediocre men under the exceptional circumstances of Pandemic and what are the surfacing pros and cons ascribed to the preventive measures like lock- down, quarantine and social distancing.
Design, molecular modeling, synthesis and biological evaluation of novel pyrazole based schiff Bases as fungal biofilm inhibitors
Authors: Sangshetti Jaiprakash Navnath
Published: September 2022

We designed series of pyrazole based Schiff bases on the basis of Bioisosteric replacement principle and validated for drug likeness using Absorption, Distribution, Metabolism, and Excretion (ADMET) criteria. The designed Schiff bases who have excellent pharmacokinetics properties, Low toxicity when In-silico analyzed for inhibition potential using molecular docking study. The top hit of molecular docking having free energy of binding in between -6.95to -4.28 kcal/mol was synthesized and biologically evaluated for fungal biofilm inhibition and minimum inhibitory concentration. The invitro biological assay of synthesized Schiff bases suggesting antibiofilm activity of Schiff base MPY10 inhibitory concentration (IC50=41.7μM) and MPY1 (IC50=44.7μM) very much equivalent to standard drug Fluconazole. The inhibition potential of MPY10 (MIC=42.6μg), MPY1 (MIC=54.4μg), MPY2 (MIC=58.1μg), MPY6 (MIC=61.8μg) and MPY4 (MIC=64.2μg) reproduces the molecular docking results shown against c. albicans biofilm drug target secreted aspartic proteinases (Sap5) signifying antifungal activity as that of standard.
Effect of proprioceptive neuromuscular facilitation stretching versus aerobic training on glycosylated hemoglobin (HbA1C) in patients with type 2 diabetes mellitus
Authors: Sethi Jasobanta
Published: September 2022

The study aimed to compare the effect of Proprioceptive neuromuscular facilitation stretching Vs. Aerobic training on HbA1c levels in patients with type 2 diabetes mellitus. Forty sedentary type 2 diabetes mellitus patients (22 males & 18 females) were randomly allocated in Aerobic Training group(n=20) and Proprioceptive neuromuscular facilitation stretching group(n=20) with twelve-week protocol for both the groups. Glycosylated Hemoglobin (HbA1c) was measured before and after the intervention to examine the effect on blood glucose level. Both Aerobic training and Proprioceptive neuromuscular facilitation stretching induced decrease in blood glucose levels (Glycosylated Hemoglobin HbA1c) after the protocol (P< .001). There was no significant difference between the two groups (P>0.001). This study shows that both Aerobic training and Proprioceptive neuromuscular facilitation stretching reduced blood glucose levels. There is no significant difference between the two interventions. Proprioceptive neuromuscular stretching may be an alternative to aerobic training to those patients who are unable to perform aerobic training to control blood glucose levels.
Bactericidal activity of lactic acid Bacillus in presence of oxide nanoparticles
Authors: Mukherjee Nabanita
Published: September 2022

The bactericidal activity of human beneficial gut bacteria commonly known as probiotics plays an important role in the era of multidrugresistant bacteria as the rising antimicrobial resistance has been identified as a top health threat. The probiotic organism plays an important role not only in infection but also in the development of immunity and its impact on inflammatory diseases. Besides digestion and absorption, it eliminates pathogenic microorganisms by their bactericidal activity and thus maintains a proper balance in the gut ecosystem. Along with that, multiple applications of nanotechnology in the agri-food sector, drug delivery, and medical sectors are growing rapidly. The biosafety study of those nanoparticles was tested on several human cell lines, but the fate and behaviour of nanoparticles in the human gastrointestinal tract, especially on beneficial gut flora or probiotics need attention along with its antimicrobial activity. Here, in this study we have tested the effect of titanium dioxide (TiO2), silicon dioxide (SiO2) and zinc oxide (ZnO) nanoparticles (as those nanoparticles used mostly in the agri-food sectors and health sectors) treated Bacillus coagulans (used as probiotic) cellular supernatant on E. coli MTCC 1610 strain with respect to untreated Bacillus coagulans cellular supernatant. We found reduced bactericidal activity in the case of TiO2 and SiO2 nanoparticles treated Bacillus coagulans whereas the bactericidal activity of ZnO nanoparticles treated Bacillus coagulans cellular supernatant showed more or less similar result with respect to untreated Bacillus coagulans cellular supernatant. Hence, the bactericidal activity of nanoparticle-treated Bacillus coagulans was studied thoroughly.
Analytical method development and validation of related substances by rphplc of sofosbuvir and velpatasvir tablets
Authors: Bhatt Jay
Published: September 2022

The developed method was a simple, accurate, precise, specific and robust method for the validation of Sofosbuvir and Velpatasvir Tablets by reverse phase high pressure liquid chromatography. For Sofosbuvir and Velpatasvir Tablets Chromatography was performed on Agilent 1200 series, UV and PDA Detector, Waters X-bridge C18 (150 mm x 4.6 mm, 3.5 µm) by using Mobile Phase A contains Buffer solution (0.6% Trifluroacetic acid in water adjusted pH to 2.2±0.05) : Acetonitrile (95:5)%v/v and Mobile Phase B contains mixture of purified water, methanol and acetonitrile in the ratio of (20: 30: 50) % v/v/v. at a flow rate of 1.0 mL/min and at 263 nm for Sofosbuvir and 320 nm for Velpatasvir wavelength. The retention times of About 48.0 minutes for Sofosbuvir and About 78.8 minutes for Velpatasvir respectively. Methyl Uridine and Impurity at RRT 0.39 found linear over the range of LOQ - 150 % of target concentration. Method also found precise by spiking impurities at specification level. Accuracy was demonstrate at LOQ - 150 % level by preparing sample in triplicate for each level and found accurate. Hence, the method could be successfully used for the analysis Impurities in Sofosbuvir and Velpatasvir Tablets Tablet.
Problematik aksebilitas pemilih penyandang disabilitas sensorik pada pemilihan umum Walikota Kota Semarang Tahun 2020
Authors: Putranti Honorata Ratnawati Dwi , Christiani Charis , Pudjiarti Emiliana Sri
Published: September 2022

Salah satu permasalahan di dalam Pemilihan Umum maupun PILKADA adalah persoalan pengumpulan data, proses pemungutan suara untuk para penyandang disabilitas. Salah satunya adalah penyandang disabilitas sensorik yang termasuk didalamnya adalah tuna rungu, tuna wicara tuna netra. Permasalahan yang dihadapi para penyandang Tuna netra pada saat pemilihan Umum ada beberapa hal yang perlu terus menjadi perhatian untuk selalu di evaluasi untuk menjadi yang lebih baik di pemilihan umum di masa-masa yang akan datang. Metode pengabdian ini dengan pendekatan kualitatif yang merupakan pendekatan dengan wawancara mendalam untuk bisa menggali lebih dalam tentang problem dan persoalan yang terjadi untuk disabilitas sensorik. Sumber data adalah penyandang disabilitas sensorik sebanyak 8 orang di Kota Semarang yang mengikuti pemilihan Walikota 2020 Kota Semarang. Sumber data Bertempat tinggal di kota semarang. Hasil yang didapatkan bahwa akasebilitas untuk logistik penyandang disabilitas sensorik perlu diperhatikan, bahwa tidak semua penyandang disabilitas dapat membaca huruf braile, dan pada saat pemilihan walikota 2020 terjadi pandemic covid, protokol kesehatan masker dan kaos tangan kesulitan bagi penyandang disabilitas sensorik. Butuh pendampingan karena mungkin informasi tidak terdengar atau menuju tempat perlu petunjuk khusus (tali) untuk memandu bagi tuna netra.
أصول التفسير عند الشيخ أمين أحسن الإصلاحي رحمه الله (دراسة تحليلية نقدية)
The Principles of Quranic Exegesis According to Shaikh Amin Ahsan Islahi (A Critical Analytical Study)
Authors: Mahmood Asif
Published: September 2022

This research comprises of the principles of exegesis according to Sheikh Amin Ahsan Islahi - may Allah have mercy upon him -. There is no doubt that the Holy Quran is a book of guidance and we desperately need to understand it to receive His guidance. Many Arab and non-Arab scholars have tried to interpret the Holy Quran and have chosen a variety of methodologies and specific principles so that people know Allah’s commands and prohibitions. Among these scholars is Sheikh Amin Ahsan Islahi who interpreted the Holy Qur’an in a new way and chose definite and indefinite principles for the interpretation of the Book of Allah. What are the principles that Sheikh Islahi focused on? What are the definite and indefinite principles according to him? What are the methods that he chose to explain the meanings, rulings and wisdom of the Qur’an? Is he appreciated or blamed for those principles? According to these questions, the researcher will answer them in a critical analytical study based on traditional and rational evidence.
ختم نبوت کے تقاضے قرآن و سنت کی روشنی میں
Requirements of the Finality of Prophethood in the light of the Quran and the Sunnah
Authors: Al-Azhari Salauddin Sani , Sani Toba
Published: September 2022

The belief in the Finality of Prophethood is the belief on which the foundation of Islam stands, even a slight crack in this faith is enough to destroy Islam. The Prophet (PBUH) is a universal Prophet and He came with the universal book and law.
We have described four reasons for the End of Prophethood in this article. Although the Finality of Prophethood is proved by 110 Quranic verses, some of its examples are presented in the article. And it has also been proved through Ahadees-e-Mutawatira.
According to the famous saying, one lac and twenty-four thousand Prophets and messengers were sent to guide the people in the world. A question arises here that no prophet came after The Last Prophet Muhammad (SAWW) the Messenger of Allah, so how can the Ummah be guided now? We have answered this question in the article that prophethood has ended but its influence continues even today in the form of the caliphate, true dream, and Mujaddid scholars (Ulama).
We have also described the types of deniers of the end of prophethood in the article and made it clear that no type of denial is acceptable. A great war was fought in the history of Islam against the claimant of the end of Prophethood, Musailma Qazab, 28000 Muslims were martyred. Islam always teaches moderation; therefore, Islam has always taken the path of dialogue so that the claimants of prophethood can take the right path.
Prophet (peace be upon him) is the last and universal prophet. After them, anyone who claims prophethood and his followers are all disbelievers, but not every follower is liable to death.
PENTINGNYA ANALISIS BIAYA KUALITAS TERHADAP KUANTITAS KERUSAKAN PRODUK PADA PT NUSANTARA
Authors: Retno Udaninsih
Published: September 2022

Persaingan bisnis yang begitu kompetitif saat ini menuntut setiap perusahaan untuk mampu bersaing, agar perusahaan bisa bertahan hidup, berkembang dan mencapai tujuan yang diinginkan yaitu memperoleh laba yang optimal. Oleh karena itu peranan akuntansi manajemen dalam masalah pengendalian kualitas atas produk yang dihasilkan menjadi perhatian utama. Pelaksanaan pengendalian kualitas tidak lepas dari biaya kualitas yang harus dikeluarkan oleh perusahaan, karena untuk menghasilkan kualitas yang tinggi dibutuhkan biaya kualitas yang  terdiri dari biaya pencegahan, biaya penilaian, biaya kegagalan baik internal maupun eksternal. Kegiatan pengendalian tersebut diharapkan dapat meningkatkan kualitas sehingga diperoleh output yang benar-benar baik, sehingga akan menekan atau mengurangi jumlah produk yang rusak, karena apabila dalam proses produksi banyak terjadi produk rusak, maka perusahaan akan mengalami kerugian yang diakibatkan oleh banyaknya biaya, tenaga waktu yang dikeluarkan. Dengan dikeluarkannya biaya kualitas diharapkan dapat menekan kerugian yang disebabkan oleh produk rusak. Metode penelitian yang digunakan dalam penelitian ini yaitu pendekatan kualitatif dengan alasan tidak menggunakan pengujian statistik  Ruang lingkup penelitian ini yaitu membahas pengendalian kualitas dan biaya kualitas   untuk produksi jenis square pile. Dari hasil penelitian  menunjukkan bahwa biaya kualitas yang telah dikeluarkan perusahaan sudah cukup efisien karena perbandingan total biaya kualitas terhadap penjualan masih dibawah standar yang ditetapkan yaitu 2,5 %  dimana pada tahun 2012 sebesar 1,39 %, tahun 2013 sebesar 1,58 % dan tahun 2014 sebesar 1,18 % dari penjualan.Dan tingkat kerusakan produk dari tiga tahun  tersebut menurun dan masih dibawah standar yang ditetapkan yaitu 1 %, dimana pada tahun 2012 sebesar 0,47 %, tahun 2013 sebesar 0,62 % dan tahun 2014 sebesar 0,45 %.
Sistem Jual Beli Kelapa Sawit oleh Peron CV Ibrahim Putra di Pangkalan Dewa Persfektif Ekonomi Syariah
Authors: Rahmad Kurniawan  , Indah Dwi Ristiana Putri
Published: September 2022

The platforms are usually owned by individuals, in the village of Pangkalan Dewa, West Kotawaringin Regency, there are 5 palm oil platforms, one of which is the CV Ibrahim Putra platform. Many farmers sell their oil palm harvests to the CV Ibrahim Putra platform, this can be seen from the farmer data in 2021 that there are 200-250 permanent farmers who sell their oil palm harvests to the CV Ibrahim Putra platform. on the other platforms there are less than 100 farmers. This type of research is field research. Subjects consist of employees and farmers who sell their crops to the CV Ibrahim Putra platform. The technique of determining the subject is purposive sampling. The data analysis is data collection, data reduction, data presentation, and conclusion drawing and verification. The buying and selling system of the CV Ibrahim Putra platform is to pick up the fruit to the farmer's land or the farmer delivers it directly to the CV Ibrahim Putra platform, then the fruit is weighed using a ram scale, the fruit that has been weighed will be paid by the platform in cash with a receipt of the sale. The buying and selling system of the CV Ibrahim Putra platform in terms of transactions and pricing is legal according to Islam because there are no violations of Islamic sharia provisions. The presence of the CV Ibrahim Putra platform has a positive value for farmers and can improve the economic welfare of oil palm farmers.
PENGARUH KOMITMEN ORGANISASI, KUALITAS PELAYANAN DAN KINERJA PEGAWAI TERHADAP KEPUASAN MASYARAKAT PADA LEMBAGA PEMASYARAKATAN KELAS IIA PADANG
Authors: Yozi Rahmat Denus  , Yulihasri Yulihasri
Published: September 2022

This study aims to determine the effect of organizational commitment, service quality, and employee performance on community satisfaction on employees of the Class IIA Padang Penitentiary. The method used in this research is quantitative research with a descriptive approach. The population in this study were employees of the Class IIA Penitentiary in Padang. The sample used was 144 people using a saturated sampling technique (census). The data analysis technique is multiple linear regression. The results showed that: (1) Organizational commitment has a positive and significant effect on community satisfaction. (2) Service quality has a positive and significant effect on community satisfaction. (3) Employee performance has a positive and significant effect on community satisfaction. (4) Organizational commitment, service quality, employee performance together have a positive and significant effect on community satisfaction in the Class IIA Padang Penitentiary.
PENGARUH MANAJEMEN BAKAT, MANAJEMEN PENGETAHUAN, PENILAIAN KINERJA, KEPRIBADIAN DAN KREATIVITAS TERHADAP PENGEMBANGAN KARIR PEGAWAI KANTOR KEMENTERIAN AGAMA KABUPATEN PADANG PARIAMAN
Authors: Helda Marini  , Evi Susanti Tasri
Published: September 2022

This study aims to determine the effect of Talent Management, Knowledge Management, Performance Assessment, Personality, and Creativity on the Career Development of the Ministry of Religion's Office employees, Padang Pariaman Regency. The population in this study were all employees the Ministry of Religion, Padang Pariaman Regency, with as many as 62 people. By using the Multiple Linear Regression method. The results of this study indicate that talent management has a positive influence on employee career development at the Office of the Ministry of Religion of Padang Pariaman Regency, Knowledge management has a positive influence on the career development of employees of the Ministry of Religion Office of Padang Pariaman Regency, Performance appraisal has a positive influence on employee career development. Office of the Ministry of Religion of Padang Pariaman Regency, Personality has a positive influence on the career development of employees of the Office of the Ministry of Religion of Padang Pariaman Regency, Creativity has a positive influence on the career development of employees of the Office of the Ministry of Religion of Padang Pariaman Regency.
ANALISIS FAKTOR FUNDAMENTAL YANG MEMPENRAUHI RETURN PERUSAHAAN RITEL
Authors: Heri Sasono  , Muhammad Hendra Apriwarto
Published: September 2022

The company's performance can be seen from the profitability and sustainability in maintaining its business, especially retail companies. The purpose of this study was to examine the influence of factors that affect the performance of retail companies, such as DER, NPM and TATO. The population of this research is 25 companies and the research sample is 8 companies on the Indonesia Stock Exchange (IDX).The research method uses Normality Test, t test, Anova test, Coefficient of Determinants, Correlation and Multiple Linear Regression using SPSS software version 22.

The results of the research Net Profit Margin (NPM) and Total Asset Turnover (TATO) have a significant effect on Return on Assets (ROA), while the Debt Equity Ratio (DER) has no significant effect.

However, simultaneously the three independent variables (DER, NPM and TATO) have a significant effect on Return on Assets with the equation Y = -0.015 - 0.001X1 + 1.549X2 + 0.011X3.
PENGARUH RETURN ON ASSET, LOAN TO DEPOSIT RATIO, DAN CAPITAL ADEQUACY RATIO TERHADAP HARGA SAHAM
Authors: Lucy Maya Enjela  , Ickhsanto Wahyudi
Published: September 2022

This study aims to determine the effect of Return on Assets, Loan to Deposit Ratio, and Capital Adequacy Ratio on stock prices. In this study using stock prices as the dependent variable, and with three types of independent variables, namely Return on assets, Loan to Deposit Ratio, and Capital Adequacy. The population in this study are all conventional banking sub-sector companies listed on the Indonesia Stock Exchange in 2017-2021. The sampling technique used purposive sampling, and as many as 24 companies were selected as samples. This research model uses a causal design and multiple linear regression analysis with secondary data types. The program used in this study uses the Statistical Program for Social Science (SPSS) 25 software in processing data. From these results it can be concluded that Return on Assets, Loan to Deposit Ratio, and Capital Adequacy simultaneously affect stock prices. Partially, Return on Assets (ROA) has a positive and significant effect on stock prices, Loan to Deposit Ratio (LDR) has a significant and negative effect on stock prices, and Capital Adequacy Ratio (CAR) has no effect on stock prices. Further researcher are expected to consider other variable related to stock prices or other sector and update research period for future period.
PERUMUSAN PEDOMAN INTERNALISASI NILAI-NILAI BUDAYA PERUSAHAAN DI PABRIK ROKOK SUKUN PUSAT
Authors: Tuti Ningrum  , Fera Elviana
Published: September 2022

Culture has an important role in the company. One of the elements in corporate culture is values. Companies must ensure that the culture is acceptable and even practiced by employees. PR Sukun it self has problems related to employees' understanding of their cultural values. Internalization can be used as one of the company's strategies to ensure that cultural values ​​can be accepted and implemented. Of course, guidelines are needed as the basis for the implementation of internalization. Purpose of this study is to know the guidelines formulation process for the internalization of corporate cultural values. This research uses descriptive-qualitative. Data collected by triangulation method that are interviews, documentation, and observation. The results show that PR Sukun had espoused values “Sukun Kuat”, that are (contibutive, strong, original, and tados). Moreover, this research also got information about conditions and steps for internalizing the current PR Sukun values. The results are compared with the references obtained by the writer to make recommendation. The recommendations of this guideline contain the preparation of guide or internalization materials, the formation of agents of change and their duties, planning of internalization programs, and monitoring evaluations.
SOSIALISASI BAGAIMANA MEMILIH KOSMETIK YANG AMAN DAN BAIK BAGI MASYARAKAT
Authors: Aulia Mutiara Hikmah  , Zahara Fadilla
Published: September 2022

Masyarakat pada umumnya ingin berpenampilan menarik di hadapan orang lain. Perawatan yang dilakukan diantaranya mulai dari ujung rambut sampai ujung kaki. Masyarakat memilih kosmetik biasanya karena harganya murah, iklan kosmetik yang ditampilkan menarik, ataupun melihat efek yang dihasilkan ketika rekan terdekat telah menggunakannya. Padahal, kebutuhan kosmetik tiap orang berbeda-beda bergantung dari jenis kulit orang itu. Masyarakat juga diharuskan jeli dan teliti dalam memilih kosmetik yang aman dan baik untuk dirinya. Oleh karena itu, diperlukan pengetahuan yang cukup dan baik dalam memilih kosmetik yang aman dan baik bagi masyarakat agar pembelian kosmetik itu dapat memberikan hasil semaksimal mungkin sehingga penampilan yang diinginkan dapat terwujud. Sosialisasi dilakukan di lingkungan RT 16 RW 04 Kelurahan Rawa Buaya melibatkan ibu rumah tangga dan bapak-bapak yang berusia dalam rentang 30-60 tahun. Metode yang dilakukan adalah pembagian kuisioner, presentasi materi, dan pembagian flyer yang berisi tips singkat sesuai dengan tema pendidikan. Pengetahuan masyarakat bertambah sebesar 78% setelah dilakukan pemaparan materi.