bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of Planting Media Composition and NPK Dosage on The Growth and Production of Shallots (Allium Cepa L.) Thailand Varieties
Authors: Ahmad Izzan Nabil Farid  , Helilusiatiningsih Nunuk , Tri Handayani
Published: September 2022

The purpose of this research is to analyzed the interaction between the composition of the growing media and the dose of NPK on the growth and production of shallot (Allium cepa L.).The hypothesis put forward in this study is,It is suspected that there is an interaction between the composition of the growing media and the dose of NPK on the growth and production of shallot (Allium cepa L.). The benefits that can be obtained in this study are: 1. Gaining technical experience in onion cultivation with certain treatments, 2. As a material for providing final project evaluations, 3. As a reference for the community about onion cultivation with certain treatments.This research was conducted at the UNISKA Integrated Field Laboratory Greenhouse using polybags, located in Rejomulyo Village, Kediri City District, with an altitude of 67 meters above sea level, tropical climate with an average temperature of 30ºC and has an average rainfall of 1,500–2,000 mm per year. Has a sandy loam soil type. This research was conducted using a completely randomized design (CRD) with 3×3 factorial pattern, with 9 combinations of 3 replications. Factor I is planting media, which consists of three types, and Factor II is NPK dose. From these two factors, 9 treatment combinations were obtained and repeated 3 times. There was no interaction between the composition of the growing media and the dose of NPK on the growth and production of shallots.There was a single effect, the composition of the growing media had a significant effect on the growth.
Decentralisation For Better Governance
Authors: Sachdeva J K
Published: September 2022

Public administration functions through bureaucratic organisations. The definition of bureaucracy, which is a based on the function of specialisation, has two significant components viz. communication and delegation. No plan can be executed without proper communication and delegation of authority. Communication is never complete without feedback. Delegation is never complete without decentralisation. Communication and delegation run side by side
On the Sustainability of Indiaâ€™s Growth Rate
Authors: Dash Pradyumna
Published: September 2022

The performance of GDP and its sustainability in India largely depends on sustained growth of agricultural production. But agricultural production in India is subject to high volatility due to excessive dependence on monsoon and has also been witnessing a declining trend on account of non-availability of adequate institutional credit, and a decline in public sector capital formation in agriculture. Hence, the answer to ensuring sustainable growth rate of GDP lies to a large extent in ensuring faster and sustained growth in agriculture. For that, there is a need to increase the availability of bank loans to the small and marginal farmers at reasonable cost, increase public investment in infrastructure like irrigation, power, transport, and agricultural research so that the expected growth rate of 8-9 percent may become possible and also sustainable.
National-functional paradigm: increase of language capital as a goal of language policy
Authors:   Herzen Russian State Pedagogical University, Marusenko Michael A.
Published: September 2022

The article discusses changes in linguistic ideology in the postmodern and globalization period, which led to a change in the linguistic paradigm from ethnocultural to national-functional, which arose on the basis of the developmental ideology. Language policies always have a “hidden agenda” aimed at creating language hierarchies and marginalizing language communities. In the new paradigm, the question turned out to be not only the concepts of language and languages, but also many related concepts derived from the concept of the discrete nature of a language, such as language rights, mother language, bilingualism, multilingualism, code switching, etc. The resource-oriented approach to language radically changes attitudes towards languages and language groups. Language management is viewed as an analogy of natural resource management, and language policy makers control the learning and use of languages in the same way as is done in business resource allocation models. Earlier, the spread of English was studied within the framework of the theory of language imperialism. Since the last third of the ХХ century, instead of the concept of linguistic imperialism, which had a heuristic value in the early post-colonial period, the concept of linguistic capital is used. The historical chance of the Russian Federation is the use by the absolute majority of the population of the endogenous world language. Proficiency in Russian constitutes the main share of the linguistic capital of its speakers.
About repeated motives in the book of A.P. Chekhov “Sakhalin Island”
Authors:   Ivanovo State University, Kapustin Nikolay V.
Published: September 2022

“Sakhalin Island” occupies a special place among Chekhov’s creative works, which can be explained first of all by its documentary background and genre peculiarities. It is an undeniable fact but, as the present article shows, it would be wrong to separate “Sakhalin Island” from the writer’s fiction works. On the assumption of the integrity of the creative personality, manifesting itself regardless of the genres the writer works in, the author of the article studies repeated motifs in “Sakhalin Island”. As a result, the book comes close to Chekhov’s fiction works notable for the poetics of repetition. Naturally, repetitions are not so conspicuous in the writer’s long texts in comparison with his short pieces; nevertheless, they cannot but draw attention. Varying, overlapping and interpenetrating, the repeated motifs in “Sakhalin Island” (for example, boredom, bondage, rain, sea, escape/departure from the island, etc.) not only play a compositional role but also unite people’s fortunes, thus becoming an important exponent of Chekhov’s concept of life and a characteristic of generic traits of human nature.
Creativity of Vladimir Narbut in the context of poetic trends of the first half of the 20 century
Authors:   Gorky Literary Institute, Kozhukharov Roman R.
Published: September 2022

The article presents an understanding of the originality of the poetry of Vladimir Narbut in relation to the ideological and aesthetic searches of acmeists, futurists, expressionists, oberiuts. The close relationship between the style of Narbut and the poetics of futurism is recorded in a number of literary sources, in particular, in the publications of N. Aseev, M. Zenkevich, V. Shklovsky, L. Chertkov, R. Timenchik, S. Fedyakin. The correlation of Narbut’s artistic searches and the poetic vanguard visibly manifested itself after the release in 1912 of the collection of poems “Hallelujah” and the scandalous hype that accompanied it. The rethinking of symbolist canons is carried out by the poet within the framework of the aesthetics of acmeism and “natural realism”, anticipating the “revolution of the spirit” proclaimed by the futurists and the social, October revolution of 1917. Among the authors who influenced the formation of the poetics of Narbut, it is possible to name the poets of German expressionism, first of all, G. Benn. The formal search for Narbut in the 1930s turns out to be consonant with the innovative line of Mayakovsky. Coming closer to the literature of the absurd, the artistic world of Narbut, in turn, influences the ideological and aesthetic searches of the oberiuts, N. Zabolotsky, representatives of “unofficial poetry”, in particular, members of the “L. Chertkov group”.
The motives of the works of Flaubert and Maupassant in the prose of Isaac Babel
Authors:   Gorky Institute of World Literature of the Russian Academy of Sciences, Pogorelskaia Elena I.
Published: September 2022

The article examines some motifs of G. Flaubert and G. de Maupassant in the stories of I. Babel of the 1920s and 1930s. Stylistic and genre comparisons of Babel’s works with the works of French writers were noticed by critics in the first half of the 1920s. Similarities with Maupassant in the structure of the novella, with Flaubert — in the structure of the phrase were noted. Maupassant’s novella and Babel’s novella have a lot in common, first of all, brevity, saturation, paradoxicity. However, there is a significant difference: Maupassant almost never narrates in the first person, Babel, on the contrary, in the vast majority of his stories speaks on his own behalf, while most often the narrator is the actor. At the same time, the similarity of the narrative manner of Maupassant and Babel is noted. V. Shklovsky, appreciating Babel’s stories highly, insists on their similarity to Flaubert’s historical novel Salambo. But in this case, it is hardly possible to talk about direct borrowings or allusions, rather, we can talk about random coincidences and not quite obvious roll calls in the depiction of cruelty and death during the war, about some pomp and solemnity of individual descriptions in Babel’s stories from Red Cavalry or in Odessa stories, similar to the descriptions in Salambo. This article identifies allusions to the works of Maupassant in the short stories Quaker (1920), My first Goose (1924) and allusions to the works of Flaubert and Maupassant in the story Guy de Maupassant (1932).
Perception of absurdistic texts of Achille Campanile in criticism
Authors:   Lomonosov Moscow State University, Gurenkova Julia V.
Published: September 2022

The article presents an overview of the critical reception of the work of the Italian writer of the twentieth century Achille Campanile. The relevance of this study lies in the fact that it analyzes the work of a little-known Italian writer-comedian in Russia, which has not been sufficiently studied in Russian literary criticism and in foreign science. Officially, the works of Campanile are not classified as absurdism as a direction, however, according to some critics, this author should be considered not just a predecessor, but the founder of the theater of the absurd. Accordingly, the study of the poetics of A. Campanile’s comedies is necessary from the point of view of analyzing the genesis of absurdism in Western Europe. The purpose of the study is to comprehend the role and significance of the author’s heritage in the history of Italian and world literature. The main methodological basis of the study is a combination of biographical, historical-literary, historical-cultural and comparative research methods. The materials presented in the article allow us to conclude that in the work of A. Campanile, some critics identify common features with futurism, surrealism and absurdism. Researchers of Campanile’s work generally highly appreciate the talent of the writer, highlight the main techniques used by the author to create a comic effect, a feature of the style and language of the works.
“How we built the subway”: about one story of the project “History of factories and plants”
Authors:   Gorky Institute of World Literature of the Russian Academy of Sciences, Bystrova Olga V.
Published: September 2022

The work is devoted to two books on the history of the metro, published in 1935 — “Stories of the builders of the subway” and “How we built the subway”. Both books were created within the framework of the project “The History of factories and plants”, conceived and implemented by M. Gorky. The history of books studied in the article covers extensive materials (fiction, memoirs, epistolary, documentary, etc.) and at the same time is strategically important for the development of the topic of labor in Soviet literature. The problem of the writer's organizational activity aimed at rallying the writing teams working on production collections is touched upon. The sources of information were documents from the Archive of A.M. Gorky (IMLI RAS) and OR IMLI, which are published for the first time. These ego documents provide additional, previously unknown, material for the study of the project “History of factories and plants”, and also allow you to restore individual episodes of the 1930s. All this allows us to conclude that the stated topic is one of the important strategic directions in the study of the literary process of the twentieth century. When studying the problem, a set of methods of source analysis was used, while biographical, memoir, epistolary and other materials served as sources
Cidadelas da ordem & outros escritos
Authors:   Universidade Estadual de Campinas, Cunha Maria Clementina Pereira
Published: September 2022

A obra reúne um pequeno livro e três artigos avulsos, originalmente publicados entre 1990 e 2000. Produzidos sem intenção de constituir uma unidade, estes textos possuem um eixo comum: a relação entre a consolidação do novo regime político que emerge em novembro de 1889 no Brasil e a implantação e desenvolvimento de instituições fundadas em diversos ramos do saber acadêmico, particularmente a medicina mental e os hospícios científicos. Tais instituições de reclusão, bem como as prescrições escoradas na cientificidade do período, foram alicerces sólidos para a construção da nova forma republicana de dominação. Com essas bases, o novo regime pode se manter fortemente excludente, naturalizando e justificando por outros caminhos as desigualdades de classe, raça e gênero que caracterizavam a dominação escravista e patriarcal.
Perfil dos estudantes de odontologia no uso do instagram como ferramenta de aprendizagem móvel e ubíqua
Authors: Araújo Maria Teresa Borges , Novais Veridiana Resende , Carvalho Thiago de Amorim
Published: September 2022

Objetivo: Caracterizar o perfil de uso do Instagram como ferramenta de aprendizagem ubíqua por parte dos estudantes de Odontologia de instituições de ensino públicas e privadas. Método: Trata-se de um estudo transversal, quali-quantitativo, prospectivo, exploratório, utilizando um questionário estruturado, sobre o uso do Instagram como ferramenta de aprendizagem por estudantes de uma Instituição de Ensino Superior Pública (Universidade Federal de Uberlândia) e uma Instituição de Ensino Superior Privada (Centro Universitário de Patos de Minas) com estudantes do primeiro ao último ano do curso de Odontologia. As análises estatísticas foram realizadas através do software Bioestat versão 5.3, e o nível de significância foi igual 5% ou (p=0,05). Resultado: As características sociodemográficas revelaram que a maioria dos estudantes de Odontologia são mulheres, jovens e brancas. A frequência do uso do celular é média de 5 horas diárias (38,2%). A rede mais acessada é o Instagram (33,5%) e a maioria dos estudantes tem facilidade (44,7%) ou muita facilidade (44,1%) em acessar conteúdos sobre saúde bucal nas redes sociais. A maior parte dos entrevistados se preocupa em visualizar conteúdos com evidência científica (44,4%). Conclusão: Demonstra-se que o Instagram pode ser uma ferramenta útil para o processo ensino-aprendizagem, já que estudantes relatam seu uso para atividades acadêmicas e que professores devem estimular o uso dessa mídia social, mesmo após o retorno do regime presencial.
A BNC-formação e a formação docente em cursos de licenciatura na Universidade Brasileira
Authors: Giareta Paulo Fioravante , Ziliani Arlete Cristina Motovani , Silva Ligiane Aparecida da
Published: September 2022

Este trabalho tem por objeto a pedagogia universitária para a formação de professores no âmbito da Resolução No 2, de 20 de dezembro de 2019, a Base Nacional Comum para a Formação Inicial de Professores da Educação Básica (BNC-Formação). Para tanto, objetiva apresentar uma análise do possível impacto das novas diretrizes curriculares para a formação de professores nos cursos de Licenciatura na universidade brasileira. Metodologicamente, o trabalho apresenta-se como exercício analítico-crítico, estruturado a partir do materialismo histórico-dialético e com aporte teórico nas concepções de Gramsci (1968, 2002). A pesquisa indica o desenho de uma lógica homogeneizante para a política de formação de professores da BNC-Formação, produzida a partir da intelectualidade orgânica do capital e focada em uma pedagogia de resultados, com explícita intencionalidade de reduzir os espaços para pensar a formação para a docência em uma perspectiva de promoção cultural, da expressão e da organização da práxis social da atividade humana das classes subalternas e de uma pedagogia capaz de promover uma articulação indissociável entre as dimensões técnica, científico-pedagógica e sociopolítica da formação de professores.
Machine learning-accelerated first-principles predictions of the stability and mechanical properties of L12-strengthened cobalt-based superalloys
Authors: Xi Shengkun , Yu Jinxin , Bao Longke , Chen Liuping , Li Zhou , Shi Rongpei , Wang Cuiping , Liu Xingjun
Published: September 2022

As promising next-generation candidates for applications in aero-engines, L12-strengthened cobalt (Co)-based superalloys have attracted extensive attention. However, the L12 strengthening phase in first-generation Co-Al-W-based superalloys is metastable and both its solvus temperature and mechanical properties still need to be improved. Therefore, it is necessary to discover new L12-strengthened Co-based superalloy systems with a stable L12 phase by exploring the effect of alloying elements on its stability. Traditional first-principles calculations are capable of providing the crystal structure and mechanical properties of the L12 phase doped by transition metals but suffer from low efficiency and relatively high computational costs. The present study combines machine learning (ML) with first-principles calculations to accelerate crystal structure and mechanical property predictions, with the latter providing both the training and validation datasets. Three ML models are established and trained for predicting the occupancy of alloying elements in the supercell and the stability and the mechanical properties of the L12 phase. The ML predictions are evaluated using first-principles calculations and the accompanying data are used to further refine the ML models. Our ML-accelerated first-principles calculation approach offers more efficient predictions of the crystal structure and mechanical properties for Co-V-Ta- and Co-Al-V-based systems than the traditional counterpart. This approach is applicable to expediting crystal structure and mechanical property calculations and thus the design and discovery of other advanced materials beyond Co-based superalloys.
Fintech adoption: Its determinants and organizational benefits in Indonesia
Authors: Urumsah Dekar , Ispridevi Rintan Falah , Nurherwening Aris , Hardinto Wirawan
Published: September 2022

Financial Technology (Fintech) has become an essential issue in the past few years, especially for the companies that offer the products/services that require payment. This research explores the factors which drive companies to adopt fintech - risk perception, cost perception, organizational readiness, top management support, knowledge of information technology, customer pressure, and competitive pressure - and the benefits of its adoption. This research distributed questionnaires using purposive sampling method to the employees working in the companies adopting Fintech. There were 195 questionnaires analyzed using SEM-PLS. This research indicates that customer pressure, competitive pressure, organizational readiness, top management support, and knowledge of information technology have significant influences on Fintech adoption. However, risk perception and cost perception do not significantly affect Fintech adoption. Fintech adoption has a significant effect on organizational benefits. Companies can use this research to find the opportunities and risks when they adopt fintech in order to improve on innovating and maximize customers and partners’ satisfactions.
Identification and Prevalence of Helicobacter Pylori Virulence Genes Baba and Caga in Wolinella Isolates from the Oral Cavity of Dogs
Authors: Jahanshiri Zahra , Nayeri-fasaei Bahar , Jamshidi Shahram , Zahraei-Salehi Taghi
Published: September 2022

Wolinella spp. and Helicobacter spp. have been repeatedly reported in the oral cavity of dogs and are associated with periodontal disease. Wolinella strains predominate in the oral cavity of dogs. The only known species of this genus, Wolinella succinogenes, was considered non-pathogenic until sequence analysis of its genome revealed homologous genes resembling virulence factors in Helicobacter pylori. This has led researchers to question the nonpathogenic status of W. succinogenes. The cagA and babA genes are examples of crucial virulence factors in H. pylori pathogenesis; thus, the present study evaluated the prevalence of these genera and assessed the Wolinella strain genome in terms of the presence of these virulence factors. Multiple specific PCR tests were performed on oral secretion samples collected from 62 dogs by sterile cytobrush to evaluate the genera, species, and presence of virulence genes. The species-specific 16s rRNA genes from the Helicobacter and Wolinella genera were detected in 58.06% and 83.87% of the oral samples, respectively. H. pylori were not detected in the specimens. No cagA and babA genes were detected in the Wolinella spp. or non-pylori Helicobacter genomes. Our results confirmed that Wolinella spp. is the predominant population compared to Helicobacter in the oral cavity of dogs. Apparently, the incidence of Helicobacter infections is generally associated with non-pylori Helicobacter organisms. Despite the hypothesis of genomic homology between W. succinogenes and H. pylori, cagA and babA virulence genes were not identified in any of the oral samples from the dogs.
Evaluation of the Parenting Program in Kindergarten
Authors: Asmawulan Tri , Hastuti Isnaini Budi , Fitriyah Qonitah Faizatul
Published: September 2022

This research is motivated by the low level of understanding of parents about early childhood education. In addition, there is still a lack of synergy between the school and parents in educating children. The method used in this research is qualitative research, with interview, observation and documentation techniques. The results of this study are: a. the parenting program implemented at Al Fajar Kindergarten has generally been running according to the standard parenting activity program, namely the existence of programs related to parent meetings (KPO), parental involvement in class (KOK), parent involvement in joint events (KODAB) , parent consultation days (HKO), and home visits. c. Parenting programs that have been running at Al Fajar Kindergarten include parent meetings, involving parents or guardians in learning activities and institutional activities, consulting children's problems with school consultants, and regular home visits to children. d. The results of the parenting program implementation at Al Fajar Kindergarten show that the better the understanding of parents towards early childhood education, children's health and hygiene, and also the increasing positive synergy between the school and parents.
The Role of Mothers in Early Childhood Education amidst the COVID-19 Pandemic in Indonesia
Authors: Wahyuningsih Sri
Published: September 2022

The spread of COVID-19 impacted education sector in which teachers cannot carry out the face-to-face (offline) learning. Consequently, teaching and learning activities are conducted online which students access from home with the help of their main carers especially mothers. This study aims to explore the role of Indonesian mothers in their early childhood education amidst the COVID-19 pandemic. It reports challenges experienced by mothers in accompanying their children’s online study from home. Data were collected from semi-structured interviews with six Indonesian mothers. The study finds that the roles of mothers to their children’s online learning include providing the children’s needs in online classes, assisting children to do the assignments, managing time between house chores and kid’s schooling, and concerning for mental kid’s health and families. It is clear that Indonesian moms encountered myriad of challenges during their children’s online class in the COVID-19 pandemic time. These challenges were worsened by the lack of technical expertise, lack of training and support, lack of preparation among children, difficulties in managing the time between children’ school and other works, and problems with internet connection. This study proposes an involvement and collaboration between parents, so that online learning can be facilitated by both fathers and mothers. This collaboration is needed to ensure the successful online learning for the children, especially during the COVID-19 pandemic. 
Aplicación del Aprendizaje Basado en Retos en la Agricultura de Precisión para una agricultura sostenible
Authors: Real Moreno Severiano , Aragón Rodríguez Fernando , Castro García Sergio , Agüera Vega Juan
Published: September 2022

El Aprendizaje Basado en Retos (ABR) es una metodología que fomenta la creatividad y el pensamiento crítico mediante el planteamiento de retos relevantes para la formación del estudiante claramente identificables como situaciones reales. En la agricultura actual se están empleando nuevas técnicas y tecnologías las cuales nos permiten conocer y gestionar la variabilidad de la producción para mejorar la sostenibilidad y eficiencia de los sistemas agrícolas, conformándose la denominada agricultura de precisión (AP). Se plantea que los alumnos de 2º curso del Máster de Ingeniería Agronómica, a través del ABR y los principios de la AP, realicen una experiencia real del manejo de un cultivo. Para ello, se ha orientado el aprendizaje hacia la toma de decisiones en la Gestión de Flotas de vehículos agrícolas y la distribución variable de insumos, articulándose en cuatro actividades guía. Participaron un total de 26 alumnos, trabajándose habilidades blandas, como la comunicación, toma de decisiones y orientación a resultados, y habilidades técnicas relacionadas con el dominio agrícola y herramientas tecnológicas específicas. Se evaluaron los aspectos citados mediante un cuestionario teórico, evaluación de las actividades guía y una exposición de la solución aportada, alcanzando puntuaciones más elevadas que en cursos anteriores con metodologías convencionales.
La gamificación como herramienta pedagógica de apoyo a la docencia en el Grado en Veterinaria.
Authors: Cano Terriza David , Caballero Gómez Javier , Risalde Moya Maria de los Angeles , Jiménez Martín Débora , Paniagua Risueño Jorge , García Bocanegra Ignacio
Published: September 2022

En la última década, el interés y aplicabilidad de las Tecnologías de la Información y la Comunicación (TIC) basadas en la gamificación se han visto reflejados en el desarrollo de gran cantidad de aplicaciones digitales (Apps). El objetivo general del presente trabajo fue introducir herramientas TICs basadas en la gamificación para el autoaprendizaje en el aula en distintos cursos del Grado en Veterinaria. Durante el curso académico 2019/2020 se incluyeron dos Apps (Plickers y Socrative) en la docencia práctica de diferentes asignaturas del Grado en Veterinaria de la Universidad de Córdoba. Un total de 196 estudiantes participaron en estas actividades. La valoración general por parte del alumnado fue muy positiva (media: 9,0 y 8,8 sobre 10 para Plickers y Socrative, respectivamente). Con una puntuación de 4,8 sobre 5, el alumnado consideró de gran importancia este tipo de aplicaciones en el apoyo a la docencia. Además, con una puntuación de 4,4 y 4,8, sobre 5, el alumnado recomendaría la implantación de las Apps Plickers y Socrative, respectivamente, en la evaluación de seminarios y prácticas de otras asignaturas y repetiría la actividad con este formato (puntuaciones ≥ 4,5 sobre 5 de media). Los resultados obtenidos evidenciaron un elevado grado de satisfacción por parte del alumnado y del propio profesorado que participó en la experiencia.
Physiological and Hormonal Effects of Titanium Dioxide Nanoparticles on Thyroid Function and the Impact on Bodyweight in Male Rats
Authors: Luaibi Noori Mohammed , Mohammed Raghda Ali
Published: September 2022

Fifty-four Sprague-Dawley albino adult male rats were classified into three main groups each of 18 rats treated for a particular duration (1,2, and 4) weeks respectively. Each group was subdivided into three subgroups each of six rats treated as follows; group (1) serve as normal control, group (2, and 3) intra-peritoneal treated with TiO2NPs (50,200) mg/kg respectively, body *weight of all rats was measured before and after the experiment, then rats were dissected at the end of each experiment and the weights of the thyroid was measured. The result showed a highly significant decrease (p<0.01) in thyroid gland weight, a highly significant increase (p<0.01) in body weights and TSH, while a highly significant decrease (p<0.01) inT3 and T4 was observed in all different doses (50,200) mg/kg at durations 1,2 and 4 weeks. So, this study confirms body weight gain is associated with thyroid dysfunction.
COVID-19 Diagnosis Using Spectral and Statistical Analysis of Cough Recordings Based on the Combination of SVD and DWT
Authors: Mohammed Thabit Sultan , Sultan Awni Ismail , Alheeti Khattab M. Ali , Aljebory Karim Mohammed , Sultan Hasan Ismail , Al-Ani Muzhir Shaban
Published: September 2022

Healthcare professionals routinely use audio signals, generated by the human body, to help diagnose disease or assess its progression. With new technologies, it is now possible to collect human-generated sounds, such as coughing. Audio-based machine learning technologies can be adopted for automatic analysis of collected data. Valuable and rich information can be obtained from the cough signal and extracting effective characteristics from a finite duration time interval that changes as a function of time. This article presents a proposed approach to the detection and diagnosis of COVID-19 through the processing of cough collected from patients suffering from the most common symptoms of this pandemic. The proposed method is based on adopting a combination of Singular Value Decomposition (SVD), and Discrete Wavelet Transform (DWT). The combination of these two signal processing techniques is gaining lots of interest in the field of speaker and speech recognition. As a cough recognition approach, we found it well-performing, as it generates and utilizes an efficient minimum number of features. Mean and median frequencies, which are known to be the most useful features in the frequency domain, are applied to generate an effective statistical measure to compare the results. The hybrid structure of DWT and SVD, adopted in this approach adds to its efficiency, where a 200 times reduction, in terms of the number of operations, is achieved. Despite the fact that symptoms of the infected and non-infected people used in the study are having lots of similarities, diagnosis results obtained from the application of the proposed approach show high diagnosis rate, which is proved through the matching with relevant PCR tests.  The proposed approach is open for more improvements with its performance further assured by enlarging the dataset, while including healthy people.
Analysis of Adipokines and some Steroid Hormones in Myocardial Infarction
Authors: Yousif Araz M , Ismail Parween A , Ismail Chalak A
Published: September 2022

The most common cause of death is cardiovascular disease (CVD), with ischemic heart disease being the most notable type.  There is a propensity to raise the sensitivity of methods in contemporary laboratory for diagnosing of CVD, and assessing key as CVD bio-indicators. The urgent task is to seek for different indicators as a hopeful tool for early detection and monitoring of myocardial infarction in blood samples only. This study comprised 117 Volunteers, recorded with both genders in the age range of 32-64 years old. The volunteers were categorized into two groups: 67patients of myocardial infarction, other group embraced 50 healthy individuals. The samples of blood were collected and directed for biochemical analysis to evaluate estradiol, testosterone, progesterone, adiponectin, leptin, and lipid profile [total cholesterol, triglycerides, high density lipoprotein (HDL), and low-density lipoprotein (LDL)] levels in each group. The following conclusion can be drawn from this study based on statistical assessment of bio-indicator parameters, significantly reduced of testosterone and HDL (P <0.001) levels in myocardial infarction, within non-significantly elevated P <0.061 of progesterone levels in myocardial infarction patients as compared with healthy individuals. The remaining biochemical tests indicated significantly elevated levels in patients with myocardial infarction such as estradiol (P <0.001), adiponectin (P <0.001), leptin (P <0.001), total cholesterol (P <0.001), triglycerides (P <0.001) and LDL (P <0.001) levels. Adipokines (adiponectin, leptin) and some steroid hormones (estradiol, testosterone) show crucial roles in the improvement of metabolic and cardiovascular diseases and may be utilized as bio-pointer for myocardial infarction exposure, medical conduct and severity. This acknowledgment offers early diagnosis of disease and progression.
Honeyword Generation Using a Proposed Discrete Salp Swarm Algorithm
Authors: Yasser Yasser A. , Sadiq Ahmed T. , AlHamdani Wasim
Published: September 2022

Honeywords are fake passwords that serve as an accompaniment to the real password, which is called a “sugarword.” The honeyword system is an effective password cracking detection system designed to easily detect password cracking in order to improve the security of hashed passwords. For every user, the password file of the honeyword system will have one real hashed password accompanied by numerous fake hashed passwords. If an intruder steals the password file from the system and successfully cracks the passwords while attempting to log in to users’ accounts, the honeyword system will detect this attempt through the honeychecker. A honeychecker is an auxiliary server that distinguishes the real password from the fake passwords and triggers an alarm if intruder signs in using a honeyword. Many honeyword generation approaches have been proposed by previous research, all with limitations to their honeyword generation processes, limited success in providing all required honeyword features, and susceptibility to many honeyword issues. This work will present a novel honeyword generation method that uses a proposed discrete salp swarm algorithm. The salp swarm algorithm (SSA) is a bio-inspired metaheuristic optimization algorithm that imitates the swarming behavior of salps in their natural environment. SSA has been used to solve a variety of optimization problems. The presented honeyword generation method will improve the generation process, improve honeyword features, and overcome the issues of previous techniques. This study will demonstrate numerous previous honeyword generating strategies, describe the proposed methodology, examine the experimental results, and compare the new honeyword production method to those proposed in previous research.
Some K-Banhatti Polynomials of First Dominating David Derived Networks
Authors: Mekala Anjaneyulu , U Vijaya Chandra Kumar , Murali R.
Published: September 2022

Chemical compounds, characteristics, and molecular structures are inevitably connected. Topological indices are numerical values connected with chemical molecular graphs that contribute to understanding a chemical compounds physical qualities, chemical reactivity, and biological activity. In this study, we have obtained some topological properties of the first dominating David derived (DDD) networks and computed several K-Banhatti polynomials of the first type of DDD.
Exploring the Relationship between Faculty Mentor Engagement and African American STEM Persistence
Authors: Harris Pheather R. , Nagle Barry
Published: September 2022

This quantitative study explores factors associated with the persistence rates of African American students aspiring to major in STEM subjects and who ultimately complete undergraduate STEM degrees. The primary data source for this study is the Cooperative Institutional Research Program’s 2009 The Freshman Survey (TFS) and the 2013 College Senior Survey (CSS). The sample included 379 African American students who indicated on TFS that they intended to declare STEM as their major. The findings reveal that African American undergraduates are significantly more likely to persist in STEM majors with increased levels of faculty mentor engagement. The findings demonstrate the need for institutions to implement curricula that encourage meaningful faculty engagement to contribute to the creation of more inclusive academic environments for African American students in STEM.
A comparison of NAFLD and MAFLD diagnostic criteria in contemporary urban healthy adults in China
Authors: Liu Qiling , Zhao Gang , Li Qian , Wu Weiyun , Zhang Yan , Bian Hua
Published: September 2022

Background
A recently proposed diagnostic criteria of metabolic dysfunction-associated fatty liver disease (MAFLD) is more available for various clinical situations than nonalcoholic fatty liver disease (NAFLD), but understanding about MAFLD prevalence and the characteristics of the examination results remain limited in the general adult urban population in China.
Methods
A total of 795 subjects were recruited from Wu Song Branch of Zhongshan Hospital who participated in general health assessment. Of these patients, 369 were diagnosed with fatty liver disease by abdominal B-ultrasonic examination. Information on other examination results was obtained through a questionnaire survey and analysis of blood samples.
Results
Among the 795 people investigated, no significant differences in the prevalence, weight, age, fasting blood glucose, glycated haemoglobin, blood lipid profile, liver enzyme examination, percentage of overweight, diabetes, hypertension or dyslipidaemia were foundbetween NAFLD and MAFLD patients. Patients with MAFLD had worse metabolic disorders than NAFLD+ MAFLD- patients. The NAFLD fibrosis score (NFS) of NAFLD+ MAFLD- group were lower than NAFLD- MAFLD+ group.
Conclusions
Compared with the diagnostic criteria of NAFLD, the MAFLD definition are highly consistent. These criteria can identify a group of people who have not been diagnosed with NAFLD due to excessive drinking or other chronic liver diseases. They have high risks of metabolic disorders and liver fibrosis.
The Effects of Ionotropic GABA Receptor Blockage on Brain in Sepsis-induced Rats
Authors: Ates Gulten , Ozkok Elif , Gundogan Gul Ipek , Tamer Sule
Published: September 2022

Encephalopathy develops following sepsis, which is defined as life-threatening organ failure due to the irregular response of a host to infection. It has high mortality and morbidity rates. In this study, we aimed to investigate the effects of inflammation on brain tissue, and the effects of the Gamma-Aminobutyric acid- A (GABAA) receptor antagonist bicuculline in rats with sepsis. Sepsis was experimentally generated in rats using Lipopolysaccharide (LPS). The rats were divided into four groups as control, LPS (10 mg/kg i.p.), bicuculline (1.5 mg/kg bicuculline methiodide s.c.), and LPS + bicuculline. Electrophysiologic recordings and body temperature measurements were completed at the 24th hour after injection, and blood samples were taken from the heart for measurements of biochemical parameters. TNF-α, IL-10, and GABA levels were measured using ELISA, and MDA levels were measured using the Bouge method from tissue. Tissue imaging was performed with S100-ß, NEUN, and synaptophysin antibody using immunofluorescence staining. One-way ANOVA and the Tukey test were used in statistical analysis. Inflammatory parameters significantly increased in brain tissue in the LPS group compared with the other groups. The immunofluorescence staining results in brain tissue were as follows: S-100ß involvement increased, and NeuN and synaptophysin involvement decreased in the LPS group. In electrophysiologic recordings, activity consistent with acute non-focal seizures was observed in the LPS group; however, resting status in others. We suggest that the GABAA antagonist bicuculline methiodide may be a prophylactic agent in sepsis, which caused the impaired neurotransmitter balance, increased pro-inflammatory cytokine and lipid peroxidation, and decreased anti-inflammatory cytokine levels.
Molecular identification and phylogenetic characterization of A-strain isolates of Maize streak virus from western Ethiopia
Authors: Ketsela Daniel , Oyeniran Kehinde Adewole , Bekele Berhanu , Fontenele Rafaela S , Kraberger Simona , Varsani Arvind
Published: September 2022

The A-strain of Maize streak virus (MSV) causes maize streak disease (MSD) which is a major biotic threat to maize production in sub-Saharan Africa. Previous studies have described different MSV strains of economic importance from southern and eastern African countries, and how eastern African regions are hubs for MSV diversification. Despite these efforts, and lack of extensive sampling, there is limited knowledge about the MSV-A diversity in Ethiopia. Here, field sampling of maize plants and wild grasses with visible MSD symptoms were carried out in western Ethiopian regions of Gambela, Oromia, and Benishangul-Gumuz, during the maize growing season of 2019. The complete genomes of MSV isolates (n = 60) were cloned and Sanger sequenced. We use a model based phylogenetic approach to analyse 725 full MSV genome sequences available in the GenBank together with newly recovered genomes from Ethiopia to determine their subtypes and recombinant lineages. Of the 127 fields accessed, MSD prevalence was highest at 96% in Gambela region, and lowest in Oromia at 66%. Highest mean symptom severity of 4/5, (where 5 is the highest and 1 the lowest) was observed for both Gambela and Benishangul-Gumuz. Our results show that these newly determined MSV isolates belong in the recombinant lineage V of the A1 subtype with the widest dissemination, and economic significance in the sub-Saharan Africa and the adjacent Indian Ocean islands.
The constitutive immune response of Long-nosed bats (Leptonycteris yerbabuenae) does not vary with sex, age, reproductive activity, and migratory habits
Authors: Rivera-Ruiz David A. , Flores-Martínez Jose Juan , Rosales Carlos , M. L. Gerardo Herrera
Published: September 2022

In contrast to birds, the relationship between migration and immune response has been scarcely studied in bats. We examined how the expression of the humoral portion of the constitutive immune response varied in a bat with partial and differential migration: the Lesser longed-nosed bat Leptonycteris yerbabuenae (Phyllostomidae). The Lesser longed-nosed bat is a nectarivorous species in which pregnant females migrate ~ 1,500 km along the Pacific Coast to northern Mexico and southern USA in spring-summer where they have their young, while males and some females remain throughout the year in west-central Mexico. We measured bacterial killing ability (BKA) in plasma of males and females throughout the year and along its geographic distribution in the Pacific coast. We also examined if BKA varied with sex, age category and reproductive activity. We found that BKA values did not vary significantly with reproductive activity, migratory behavior, sex and age. However, big interindividual variation indicates that other intrinsic factors not examined in our study might play a role in bactericidal activity. Our findings and those of previous bat studies indicate that, in contrast to other migratory vertebrates, migratory bats do not regulate the humoral portion of the constitutive immunity during migration.
Microbial eco-evolutionary responses amplify global soil carbon loss with climate warming
Authors: Abs Elsa , Saleska Scott , Ferriere Regis
Published: September 2022

Soil microbes respond to warming climates through variation in traits linked to the decomposition of soil organic matter, which impacts global soil carbon emissions. Microbial trait variation is shaped by eco-evolutionary processes; yet soil carbon models largely ignore such processes and their implications for global responses to warming. Here, we apply eco-evolutionary theory to a microbe-enzyme model to optimize a key microbial trait controlling decomposition and re-calculate soil carbon projections. Eco-evolutionary optimization leads microbes subject to warming to allocate more resources to enzyme production, which leads to faster decomposition and larger soil carbon loss, especially in cold regions. As a consequence, microbial optimization significantly amplifies global soil carbon loss by 2100 relative to current models, most strongly at high latitudes. This analysis demonstrates the potential importance of microbial eco-evolutionary dynamics in carbon-cycle feedbacks to climate change.
The China facioscapulohumeral muscular dystrophy type 1 (FSHD1) registry: rationale for and description of a nationwide, observational cohort study
Authors: Qiu Liangliang , Chen Long , Zheng Fuze , Zheng Ying , Lin Xin , He Qifang , Lin Lin , Wang Lili , Ye Zhixian , Lin Minting , Lin Yi , Fu Ying , Wang Zhi-qiang , Wang Ning
Published: September 2022

Background: Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a rare, hereditary, and progressive muscular dystrophy characterized by weakness and wasting of the facial (facio-) and shoulder-upper arm (scapulo-humeral-) muscles. The clinical severity varies from nonpenetrant/asymptomatic to disability with independent ambulation loss or even wheelchair dependence. Expansion of our knowledge of the genetic model D4Z4 macrosatellite repeat contraction leading to inappropriate expression of DUX4 has led to advances in developing targeted therapeutic strategies. Thus, clinical trial readiness is now required, particularly patient registry. However, there is no FSHD registry in China, let alone any database of the epidemiology, natural history, and clinical management of FSHD. This nationwide, longitudinal, non-interventional, rare-disease patient registry (The China FSHD1 Registry, CF1R ) was established to address the paucity of data in FSHD1 and to help inform future clinical practice and optimization clinical management.
Results: This explorative study aims to recruit all patients with a genetically confirmed diagnosis of FSHD1 in China. Practice data, including demographic factors, disease progression history, family history, and clinical and genetic features are collected; the protocol does not mandate any interventions. Patients will be continuously assessed for 10 years at 5-year intervals. Several data analyses and peer-reviewed publications are expected to be generated throughout this period.
Conclusions: The data collected within this rare-disease patient registry (CF1R) will be utilized to synthesize real-world data on epidemiological information, disease progression, and clinical and (epi)genetic information, which are vital for adequate symptom management and clinical trial-readiness of FSHD1 in China.
Ethics and dissemination
The study was granted ethics committee approval by the First Affiliated Hospital of Fujian Medical University (MRCTA, ECFAH of FMU [2020]026) in 2020. Findings will be disseminated via presentations and peer-reviewed publications. Dissemination will target different audiences, including national stakeholders, researchers from different disciplines and the general public.
Trial registration number
NCT04369209
The Influence of Two Etiological Factors of Pulp Diseases on the Success of Regenerative Endodontic Procedures in Immature Human Teeth (A Comparative in-Vivo Study)
Authors: AbdulRahman Aya , Batouty Kariem El , Nagy Mohamed
Published: September 2022

The authors have requested that this preprint be removed from Research Square.