bluuebunny/crossref_metadata_2025 huggingface dataset:
O Impacto do Campo de Cancerização no Desenvolvimento de Cancro Cutâneo
Authors: Travassos Ana Rita , Mendonça Sanches Maria , Soares-de-Almeida Luís
Published: December 2017

O conceito de campo cancerização, descrito em vários tipos de cancro, tem sido investigado de forma cada vez mais aprofundada no cancro cutâneo, podendo ser definido como o processo em que as células num determinado tecido ou órgão estão transformadas, com alterações genéticas, mas de aspeto clínico e histológico normal, numa fase prévia ao desenvolvimento de neoplasia ou coexistindo com células malignas, independentemente da clonalidade. A aplicação deste conceito na prática clínica poderá ter implicações potencialmente importantes no diagnóstico precoce, na estratificação de risco, na quimioprevenção primária e secundária, na definição de margens tumorais para tratamento e na abordagem das recidivas locais ou à distância. Este artigo apresenta uma revisão da literatura no que respeita ao conceito de campo de cancerização, destacando as suas implicações na prática clínica diária.
Síndrome de Graham-Little-Piccardi-Lasseur: Relato de Um Caso
Authors: Martins Nóbrega Monisa , Marques Feitosa Mendes Siqueira Thais , Santiago Ormay Mariana , Lago Obadi Daniel , Gripp Alexandre Carlos
Published: December 2017

A Síndrome de Graham-Little-Piccardi-Lasseur (SGLPL), variante folicular do Liquen Plano, caracteriza-se por apresentar, progressivamente: alopecia cicatricial multifocal do couro cabeludo associada a queratose folicular disseminada e hipotricose não cicatricial axilar e púbica. Os achados clínicos da síndrome podem estar presentes simultaneamente, embora a alopecia do couro cabeludo muitas vezes preceda os outros achados em meses a anos. Atinge principalmente mulheres na idade adulta, sendo considerada uma doença rara. A terapêutica desta dermatose é um desafio, apresentando resultados controversos. Relatamos o caso de uma paciente do sexo feminino, 75 anos, apresentando área de alopecia na região parietal direita, pápulas violáceas poligonais pruriginosas paravertebrais, máculas hipercrômicas com rendilhado branco na mucosa oral além de discreta diminuição dos pelos axilares. Após uso de hidroxizina associada à aplicação de propionato de clobetasol tópico e betametasona intralesional na placa alopécica observamos discreta melhoria.
Manchas Eritematosas Policíclicas de Instalação Aguda e Rapidamente Progressivas
Authors: Andrade Pedro
Published: December 2017

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PSEUDOXANTOMA ELÁSTICO: RELATO DE CASO
Authors: Gomes Maria Fernanda , Pinto Vinicius Broseghini , De Caprio Gabrielli Saab Oliveira , BALTAZAR ISABELLA LEMOS
Published: December 2017

Pseudoxantoma elástico (PXE), também conhecido como Síndrome de Grönblad-Strandberg, é uma doença hereditária rara, com uma prevalência estimada de 1: 50.000 na população em geral. O PXE é caracterizado por distúrbios da mineralização do tecido conjuntivo com a degeneração das fibras elásticas. Manifestações clínicas ocorrem envolvendo principalmente os olhos, do sistema cardiovascular, e a pele. Apresenta-se nesse relato o caso de um paciente de 61 anos, acometido por PXE, encaminhado pelo oftalmologista por diminuição da acuidade visual percebida há 5 anos.
EFEITOS CUTÂNEOS DA IONTOFORESE COM ÁGUA NÃO MINERAL NO TRATAMENTO DA HIPERIDROSE PALMAR – RELATO DE CASO
Authors: Santos Carolyne Mendes dos , Mazza Maísa Fabri , Neto Domingos Jordão , Maldonado Maria Cristina Jacomette
Published: December 2017

A sudorese excessiva, isolada ou associada, caracteriza a hiperidrose, que comumente ocorre na fronte, mãos, pés e axilas. Atinge cerca de 1% da população geral acometendo homens e mulheres de todas as idades. Apesar de sua função termorregulatória indispensável, o suor excessivo causa impacto significativo na qualidade de vida pessoal e profissional dos pacientes. É uma doença benigna, de diagnóstico essencialmente clínico, onde o tratamento pode ser conservador ou cirúrgico.Descrevemos o caso de uma paciente mulher, 27 anos, que apresentava hiperidrose palmar desde início da adolescência e que após diversos insucessos e dificuldades terapêuticas, obteve excelente resposta clínica à iontoforese com água não mineral. A paciente estava há pelo menos 1 ano sem tratamento clínico.
Implicações Terapêuticas dos Novos Conhecimentos Sobre a Fisiopatologia da Dermite Atópica
Authors: Borges Ana Sofia , Pinheiro Rita , Brasileiro Ana
Published: December 2017

A dermite atópica é uma dermatose inflamatória crónica que afeta principalmente crianças, podendo também manifestar- -se em idade adulta. Apesar de estar associada a um forte impacto na qualidade de vida, os avanços terapêuticos são ainda muito precários. Novos conhecimentos no âmbito da fisiopatologia da dermite atópica, realçando o papel crucial da disfunção da barreira epidérmica e sua relação com a desregulação imunitária, têm permitido o desenvolvimento de possíveis armas terapêuticas.
Dermatite de Contacto Alérgica em Idade Pediátrica: Estudo Retrospectivo
Authors: Cordeiro Ana Catarina , Ramos Leonor , Gonçalo Margarida
Published: December 2017

Introdução: A dermatite de contacto alérgica em idade pediátrica, habitualmente considerada pouco frequente, tem sido recentemente objecto de numerosas publicações associadas a um aparente aumento da sua prevalência. Tal pode ser devido a exposição e sensibilização mais precoce a alergénios de contacto ou à mais ampla utilização de testes epicutâneos, cruciais ao diagnóstico desta patologia.Métodos: Com o objectivo de avaliar as características e causas da dermatite de contacto alérgica em idade pediátrica, foram analisados os processos clínicos dos doentes com < 18 anos que efetuaram testes epicutâneos entre Janeiro de 2005 e Dezembro de 2014 na Unidade de Alergologia de Contacto do Serviço de Dermatologia dos HUC. Avaliaram- -se os seguintes parâmetros: sexo, idade, história pessoal e familiar de atopia, localização principal da dermatose, testes positivos a alergénios da série básica ou outros e respectiva relevância, hipótese de diagnóstico e diagnóstico final.Resultados: Foram estudados 106 doentes em idade pediátrica (3,6% do total), 68 do sexo feminino (64,2%) e 38 do sexo masculino (35,8%), quatro com idades compreendidas entre os 3 e 5 anos (3,8%), 28 entre os 6 e 11 anos (26,4%) e 74 entre os 12 e 17 anos (69,8%), 52,8% com antecedentes de atopia e 36,8% com lesões localizadas na face e/ou pescoço. Dos 106 doentes, 51 tiveram pelo menos um teste positivo (48,1%), mais frequentemente no sexo feminino por alergia ao níquel (18,9%). Seguiram-se o cobalto, a p-fenilenodiamina e a mistura de caínas (4,7%) entre os alergénios de série básica e, fora dela, o paládio positivo em cinco crianças. De notar que não observámos testes positivos ao níquel nos últimos dois anos. Doze doentes reagiram apenas a alergénios não incluídos na série básica, sobretudo medicamentos.Discussão: A alergia de contacto e dermatite de contacto alérgica antes dos 18 anos revelaram-se relativamente comuns. O diagnóstico etiológico precoce é importante para evitar a cronicidade das lesões e prevenir possíveis repercussões futuras a nível pessoal e profissional. O conhecimento dos principais alergénios nesta faixa etária poderá orientar medidas preventivas de futuras sensibilizações.
Studi Aksesibilitas Halte Bis Trans Menuju Lingkungan Inklusif
Authors: Hayati Arina , Bararatin Kirami , Indrawan Iwan Adi , Muchlis Nurfahmi
Published: December 2017

The provision of an inclusive environment was one of Sustainable Development Goals (SDG) 11 targets that was also listed in the declaration document of the 2016 NUA (New Urban Agenda) Habitat III. This was no exception for the public buildings and transport facilities provision that should meet and accommodate the needs of all users including persons with disabilities, the elderly, children, and women. Currently, Indonesia has committed to ratify and implement the CRPD, including the enactment of several regulations and the provision of access environment in public buildings. However, such implementation has not been maximized and complies with standards based on inclusion design. This paper is part of a Research-Based-Community Service to observe and evaluate bus stop and the pedestrian way in Surabaya. Yet, the discussion only highlights the result of pre-eliminary study of accessibility condition at bus stop based user paricpation. Methods of observation and environmental simulation were used to obtain research data. The results show various problems caused by lack of user participation and understanding and information on the design of accessible environment. This led to many application designs on the environment not in accordance with existing regulations and the needs of users especially those with special needs.
PERIKANAN PUKAT CINCIN TUNA SKALA KECILYANG BERBASIS DI PELABUHAN PERIKANAN PANTAI (PPP) TAMPERAN (Small Scale Tuna Purseseine Fisheries Based in Tamperan Fishing Port)
Authors: Hartaty Hety , Nugraha Budi , Styadji Bram
Published: December 2017

ABSTRACT
In general, fisheries in Indonesia is still dominated by small-scale fisheries, one of themis the purse seine fishery based in Tamperan Fishing Port. This study aims to determine aspects of purse seine fishery based on Tamperan Fishing Port such as vessel size and fishing gear, FADs , fishing ground and catches. The study was conducted in 2012 in Tamperan Fishing Port with measurement methods and direct observation and interviews with owners, skippers and crew. The results showed that the vessel of small-scale tuna purse seine fishing based in Tamperan Fishing Port have tonnage between 28-45 GT and made of wood with length 17.21-28 m, width 6-7 m, and depth 2-3 m. Nets is used have length between 250-300 m and width 8-10 m. Fishing ground is FADs at coordinates 10º-12º S and 100º-110º E, 60-100 miles from the Pacitan Bay with distance to the location of FADs about one day. The catch is dominated by skipjack about 57.27%, followed by scad26.31% and juvenile yellowfin 10.05%.

Keywords: Purse seine, small scale tuna fisheries, Tamperan

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ABSTRAK

Secara umum, perikanan tangkap di Indonesia masih didominasi oleh usaha perikanan skala kecil, salah satunya adalah nelayan pukat cincin yang berbasis di PPP Tamperan. Penelitian ini bertujuan untuk mengetahui aspek penangkapan perikanan pukat cincin yang berbasis di PPP Tamperan berupa ukuran kapal dan alat tangkap, rumpon, daerah penangkapan dan hasil tangkapan. Penelitian dilakukan pada tahun 2011 di PPP Tamperan Pacitan dengan metode pengukuran dan pengamatan langsung di lapangan serta wawancara dengan nelayan pemilik, nakhoda dan awak kapal. Hasil penelitian menunjukkan bahwa armada pukat cincin perikanan tuna skala kecil yang berbasis di PPP Tamperan memiliki ukuran tonase antara 28-45 GT dan terbuat dari kayu dengan ukuran panjang antara 17,21-28 m, lebar 6-7 m, dan dalam 2-3 m. Jaring yang digunakan memiliki panjang antara 250-300 m dan lebar 8-10 m dengan menggunakan rumpon. Daerah penangkapan berada pada koordinat 10º-12º LS dan 100º-110º BT dan berjarak sekitar 60-100 mil dari Teluk Pacitan dengan lama perjalanan menuju lokasi rumpon sekitar 1 hari. Hasil tangkapan didominasi oleh cakalang sebesar 57,27%, diikuti oleh layang 26,31% dan yuwana madidihang 10,05%.

Kata kunci: Pukat cincin, perikanan tuna skala kecil, Tamperan
Biosynthesis of Silver Nanoparticles Using Ganoderma Lucidum and Assessment of Antioxidant and Antibacterial Activity
Authors: Poudel Milan , Pokharel Rabin , K.C. Sudip , Awal Suvash Chandra , Pradhananga Rajaram
Published: December 2017

There is an increasing interest these days in the green route of synthesis of metal nanoparticles using plant extract, fungus and bacterial- mediated eco-friendly materials. Silver nanoparticles were synthesized using an intracellular extract of Ganoderma lucidum, a mushroom from Nepal then characterization of silver nanoparticles was performed. The Ag-NPs thus formed show surface plasmonic resonance with a maximum absorption band at 420 nm. Their crystalline nature was confirmed as a face-centered cubic structure by the XRD, Furthermore, SEM revealed that they were in the size range of 10-30 nm and were spherical in shape. The possible biomolecule involved in the reduction and stabilization of Ag-NPs were believed to be oxidized polyphenol, and carbonyl group, amino acid residue. Ag-NPs exhibit good antioxidant activity but showed low antioxidant in comparison to the fungal extract alone, which was studied using DPPH antioxidant assay. The effect of the colloidal silver nanoparticles solution against six human pathological bacteria was carried out by Disc diffusion method. The zone of maximum inhibition was seen in Bacillus subtilis (17.0 ± 0.13 mm) and least effective against Escherichia coli (10.1 ± 0.2 mm). Further, the results showed that Ag-NPs in combination with antibiotics have better antibacterial effect as compared with Ag-NPs alone. The maximum effect with a 3.2 and 5.3 fold increase was seen in Gentamicin and Streptomycin respectively providing the synergistic role of Ag-NPs. The results of antimicrobial studies indicated that the Ag-NPs are the metal of choice and can be effectively used in combination with antibiotics in order to improve their efficiency against various pathogenic microbes. Int. J. Appl. Sci. Biotechnol. Vol 5(4): 523-531
Psychological strategies of Veterans and service members who participate in organized sports
Authors: Peterson Sara L. , Laferrier Justin Z. , Koontz Alicia M. , Wang Hongwu , Hannan Matthew , Cooper Rory A.
Published: December 2017

Introduction: The study sought to examine the performance strategies of wounded, ill, and injured service members and Veterans who participate in the Warrior Games. Methods: The Test of Performance Strategies (TOPS) was completed by 23 men and 5 women participants on the first and last days of the Warrior Games. The participants were separated into 2 groups: those who had participated in organized sporting events for more than 1 year (experienced; n=14) and those who had less than 1 year of experience (novice; n=14). A mixed-model ANOVA was used to assess pre–post changes and the effect of experience on total TOPS scores. Results: Overall participation in the Warrior Games did not change the performance strategies used by the participants. However, experienced participants had higher post-competition sub-scale scores than novice participants in the categories of self-talk, goal setting, and activation ( p<0.05). Discussion: While participation in a single Warrior Games event did not appear to change participants' short-term psychological thought processes around competition and practice, more than 1 year of participation in organized sporting events was associated with improved skills.
Bone Mineral Density and Osteoporosis in Women of Rural and Urban Dwellers
Authors: Begum Shamim MF , Begum Rubina , Alam Rajibul
Published: December 2017

Introduction: Bone mineral density (BMD) is an important and measurable risk factor for osteoporotic fractures. Many studies showed higher bone mineral density and lower incidence of fracture in rural population compared to urban population. But all these studies were done in developed countries and very few studies were found in developing countries. This study was carried out to determine the bone mineral density (BMD) in women of both urban and rural dwellers and to evaluation the rate of occurrence of osteoporosis in these two groups.Method: A total 376 women with age range 35 to 85 were analyzed and divided in two groups. Group I rural (n204) and group II urban (n- 172), who were studied at two different Nuclear Medicine centers of Dhaka with different problems specially for low back pain and joint pain. Bone mineral density of lumbar spines (L2-L4) in anterior-posterior position and hip were measured using the Dual Energy X-Ray Absorptiometry-DEXA (Norland XR36). The T- scores were calculated and results were compared between rural and urban women. The history of physical activity, dietary intake of calcium, smoking habit, number of parity and socio-economic condition was also compared with BMD.Results:  The mean T score of lumber spines in rural group was -2.31±1.10 and in urban group was -1.78±1.03. The hip of rural group showed mean T score -3.11±1.09 and urban group -3.02±1.09. Mean bone mineral density was lower in rural women than urban but statistically no significant difference was observed between the two groups (P <0.01 and P <0.02 respectively). In rural group 39.2 % cases showed osteoporosis in lumbar spines and 76.4% cases in hip. In comparison the urban group revealed osteoporosis in lumbar spines in 22.7% cases and in hip 40.9% cases.Conclusion: This study revealed lower bone mineral density in rural women than urban in our study population but this difference is statistically not significant.Bangladesh J. Nuclear Med. 18(1): 39-42, January 2015
Characteristics of the Sliding Electric Contact of Pantograph/Contact Wire Systems in Electric Railways
Authors: Wu Guangning , Wu Jie , Wei Wenfu , Zhou Yue , Yang Zefeng , Gao Guoqiang
Published: December 2017

The sliding electric contact of pantograph/contact wire systems plays a significant part in the current collection stability and operation life of pantograph/contact wire systems. This paper addresses the evolutionary process of sliding electric contact of pantograph/contact wire systems by analyzing three key characteristics including contact resistance, temperature distribution and microstructure. The influence of electric current on contact resistance was interpreted. Furthermore, the evolution of the spatial temperature distribution of the carbon strip was obtained in the zigzag movement, while the dominant role of electric effect in temperature rise was demonstrated. In the end, the wear morphology differences under pure friction and current-carrying conditions were analyzed. The formation of radial cracks was illustrated and its influenced on the wear process was discussed.
Internal Force Response of a Pile in an Inhomogeneous Temperature Field
Authors: Zhang Dan , Wang Yian , Cheng Jian
Published: December 2017

An inhomogeneous temperature field was built in an experimental model of sand with an embedded pile. The temperature of the soil, as well as the temperature and strain on opposite sides of the pile were investigated in the process of temperature balance. The effect of the inhomogeneous temperature field on the internal force of the pile was analyzed. The experimental results show that the inhomogeneous temperature field will cause a bending deformation in the pile body according to the FBG (fiber Bragg grating) strain sensors. The distribution of the bending moment along the length of the pile is related to the temperature difference. The maximum bending moments reached −25.7 N·m when the temperature difference was about 1.3 °C. Therefore, the influence of the inhomogeneous temperature field o· the internal force of the foundation pile should be taken into account in the applications of a ground source heat pump system.
Parameters Identification and Sensitive Characteristics Analysis for Lithium-Ion Batteries of Electric Vehicles
Authors: Zhang Yun , Shang Yunlong , Cui Naxin , Zhang Chenghui
Published: December 2017

This paper mainly investigates the sensitive characteristics of lithium-ion batteries so as to provide scientific basises for simplifying the design of the state estimator that adapt to various environments. Three lithium-ion batteries are chosen as the experimental samples. The samples were tested at various temperatures (−20 ∘ C, −10 ∘ C, 0 ∘ C , 10 ∘ C , 25 ∘ C) and various current rates (0.5C, 1C, 1.5C) using a battery test bench. A physical equivalent circuit model is developed to capture the dynamic characteristics of the batteries. The experimental results show that all battery parameters are time-varying and have different sensitivity to temperature, current rate and state of charge (SOC). The sensitivity of battery to temperature, current rate and SOC increases the difficulty in battery modeling because of the change of parameters. The further simulation experiments show that the model output has a higher sensitivity to the change of ohmic resistance than that of other parameters. Based on the experimental and simulation results obtained here, it is expected that the adaptive parameter state estimator design could be simplified in the near future.
Modulatory Effects of Breed, Feeding Status, and Diet on Adipogenic, Lipogenic, and Lipolytic Gene Expression in Growing Iberian and Duroc Pigs
Authors: Benítez Rita , Fernández Almudena , Isabel Beatriz , Núñez Yolanda , De Mercado Eduardo , Gómez-Izquierdo Emilio , García-Casco Juan , López-Bote Clemente , Óvilo Cristina
Published: December 2017

Meat quality depends on tissue composition which is in turn influenced by different factors, such as diet, genotype, age, or sex. We evaluated the effects of breed, 24 h fasting, and dietary energy source (HO: oleic acid versus CH: carbohydrates) on the expression of candidate genes involved in adipogenesis, lipogenesis, and lipolysis in the adipose tissue from Iberian and Duroc growing pigs. The Iberian pigs showed greater feed intake, backfat thickness, and saturated fatty acids (SFA) content in the subcutaneous fat, whereas the Duroc pigs had greater ham weight and polyunsaturated fatty acids (PUFA) content. In both breeds, the diet induced changes in the fatty acid (FA) composition of subcutaneous fat samples. The HO group had higher monounsaturated fatty acids (MUFA) and oleic acid, and lower SFA than the CH group. Regarding gene expression, breed and feeding status (fasting versus postprandial) had significant effects on gene expression, with quantitative interactions between them, while diet showed negligible effects. In general, adipogenic and lipogenic genes were upregulated in the Iberian pigs and in postprandial samples. In contrast, the expression of lipolytic genes showed complex interaction effects. Our results agree with the phenotypic differences between the Iberian and Duroc breeds and with the inhibition of lipogenesis by fasting. Quantitative interactions between breed and feeding status effects were observed, which indicates a different response to fasting of the two breeds, with the obese Iberian breed showing a more stable expression of lipogenic genes. These results highlight the complexity of lipid metabolism regulation, especially in relation to lipolysis processes.
Chaperones and the Proteasome System: Regulating the Construction and Demolition of Striated Muscle
Authors: Carlisle Casey , Prill Kendal , Pilgrim Dave
Published: December 2017

Protein folding factors (chaperones) are required for many diverse cellular functions. In striated muscle, chaperones are required for contractile protein function, as well as the larger scale assembly of the basic unit of muscle, the sarcomere. The sarcomere is complex and composed of hundreds of proteins and the number of proteins and processes recognized to be regulated by chaperones has increased dramatically over the past decade. Research in the past ten years has begun to discover and characterize the chaperones involved in the assembly of the sarcomere at a rapid rate. Because of the dynamic nature of muscle, wear and tear damage is inevitable. Several systems, including chaperones and the ubiquitin proteasome system (UPS), have evolved to regulate protein turnover. Much of our knowledge of muscle development focuses on the formation of the sarcomere but recent work has begun to elucidate the requirement and role of chaperones and the UPS in sarcomere maintenance and disease. This review will cover the roles of chaperones in sarcomere assembly, the importance of chaperone homeostasis and the cooperation of chaperones and the UPS in sarcomere integrity and disease.
Time Series Analysis for Spatial Node Selection in Environment Monitoring Sensor Networks
Authors: Bhandari Siddhartha , Bergmann Neil , Jurdak Raja , Kusy Branislav
Published: December 2017

Wireless sensor networks are widely used in environmental monitoring. The number of sensor nodes to be deployed will vary depending on the desired spatio-temporal resolution. Selecting an optimal number, position and sampling rate for an array of sensor nodes in environmental monitoring is a challenging question. Most of the current solutions are either theoretical or simulation-based where the problems are tackled using random field theory, computational geometry or computer simulations, limiting their specificity to a given sensor deployment. Using an empirical dataset from a mine rehabilitation monitoring sensor network, this work proposes a data-driven approach where co-integrated time series analysis is used to select the number of sensors from a short-term deployment of a larger set of potential node positions. Analyses conducted on temperature time series show 75% of sensors are co-integrated. Using only 25% of the original nodes can generate a complete dataset within a 0.5 °C average error bound. Our data-driven approach to sensor position selection is applicable for spatiotemporal monitoring of spatially correlated environmental parameters to minimize deployment cost without compromising data resolution.
Fast and Sensitive Ellipsometry-Based Biosensing
Authors: Li Kewu , Wang Shuang , Wang Liming , Yu Hui , Jing Ning , Xue Rui , Wang Zhibin
Published: December 2017

In this work, a biosensing method based on in situ, fast, and sensitive measurements of ellipsometric parameters (Ψ, ∆) is proposed. Bare silicon wafer substrate is functionalized and used to bind biomolecules in the solution. Coupled with a 45° dual-drive symmetric photoelastic modulator-based ellipsometry, the parameters Ψ and ∆ of biolayer arising due to biomolecular interactions are determined directly, and the refractive index (RI) of the solution and the effective thickness and surface mass density of the biolayer for various interaction time can be further monitored simultaneously. To illustrate the performance of the biosensing method, immunosensing for immunoglobulin G (IgG) was taken as a case study. The experiment results show that the biosensor response of the limit of detection for IgG is 15 ng/mL, and the data collection time is in milliseconds. Moreover, the method demonstrates a good specificity. Such technique is a promising candidate in developing a novel sensor which can realize fast and sensitive, label-free, easy operation, and cost-effective biosensing.
Genetic Architecture of Dietary Fiber and Oligosaccharide Content in a Middle American Panel of Edible Dry Bean
Authors: Moghaddam Samira Mafi , Brick Mark A. , Echeverria Dimas , Thompson Henry J. , Brick Leslie A. , Lee Rian , Mamidi Sujan , McClean Phillip E.
Published: December 2017

Common bean (Phaseolus vulgaris L.) is the most consumed edible grain legume worldwide and contains a wide range of nutrients for human health including dietary fiber. Diets high in beans are associated with lower rates of chronic diseases such as obesity and type 2 diabetes, and the content of dietary fibers varies among different market classes of dry bean. In this study, we evaluated the dietary fiber content in a Middle American diversity panel (MDP) of common bean and evaluated the genetic architecture of the various dietary fiber components. The dietary fiber components included insoluble and soluble dietary fibers as well as the antinutritional raffinose family of oligosaccharides (RFOs; raffinose, stachyose, and verbascose). All variables measured differed among market classes and entries. Colored bean seeds had higher levels of insoluble dietary fibers with the black market class showing also the highest raffinose and stachyose content. Cultivars and lines released since 1997 had higher insoluble dietary fibers and RFO content in race Durango. Higher levels of RFOs were also observed in cultivars with type II growth habit that was a recent breeding target in Durango race germplasm. Candidate genes for dietary fiber traits, especially homologs to two main genes in the RFO biosynthesis pathway, were identified. The knowledge of diversity of dietary fibers in the MDP accompanied with the identification of candidate genes could effectively improve dietary fiber components in common bean.
Estudis etnobotànics a la comarca del Ripollès (Pirineu, Catalunya, península Ibèrica)
Authors: Rigat M. , Gras A. , Vallès J. , Garnatje T.
Published: December 2017

Este trabajo presenta una síntesis de la prospección etnobotánica llevada a cabo en la comarca del Ripollès entre los años 2004 y 2013. Mediante entrevistas semiestructuradas con 163 informantes nacidos entre 1915 y 1988, hemos obtenido información sobre nombres y usos populares de 457 táxones (incluyendo especies, subespecies y variedades), 15 de los cuales solamente han sido determinados hasta el nivel de género. Sobre estas plantas, los informantes han referido 7192 reportes de uso. En este artículo incluimos comentarios generales sobre diversos usos (medicinales, alimentarios y de otro tipo) y presentamos, en dos apéndices, el catálogo completo de la etnoflora comarcal.

[ct] Aquest treball presenta una síntesi de la prospecció etnobotànica duta a terme a la comarca del Ripollès entre els anys 2004 i 2013. A través d’entrevistes semiestructurades amb 163 informants nascuts entre 1915 i 1988, hem obtingut informació sobre noms i usos populars de 457 tàxons (comptant-hi espècies, subespècies i varietats), 15 dels quals només han estat determinats fins al nivell de gènere. Sobre aquestes plantes, els informants han fet 7192 reports d’ús. En aquest article fem comentaris generals sobre els diversos usos (medicinals, alimentaris i d’altra mena) i presentem, en dos apèndixs, el catàleg complet de l’etnoflora comarcal.
Exorciser l’homme des sciences humaines : programmes du poststructuralisme
Authors: A. Kittler Friedrich
Published: December 2017

« Exorciser l’homme des sciences humaines » constitue un manifeste dans lequel Kittler se penche sur les « Programmes du poststructuralisme ». Récapitulant deux siècles de « sciences humaines » (de l’institution philosophique des notions d’histoire, d’esprit et d’homme au xixe siècle à leur remise en cause dans la psychanalyse, la linguistique et l’ethnologie du xxe siècle), Kittler conclut à la dissémination des discours. En creux, il dessine toutefois une ligne plus radicale. Là où un exorcisme chrétien ne se conçoit pas sans la parole : celui auquel il invite fonctionne par une combinatoire quasi mécanique des sciences dont la clé est l’opérationnalisation mathématique et technique, c’est-à-dire informatique, de la négation. Le programme implicite de Kittler étant de faire l’archéologie d’un « Esprit » devenu « Légion ».
La mort de l’auteur selon Friedrich Kittler
Authors: Guez Emmanuel , Vargoz Frédérique
Published: December 2017

En 1900, Stéphane Mallarmé, Christian Morgenstern, Hugo Ball ou encore Stefan George bouleversent la création littéraire en produisant des œuvres qui semblent s’affranchir du sens en même temps qu’elles expérimentent les matérialités de la page, des lettres ou des sons. Une partie de la littérature ne se préoccupe plus d’ouvrir à un monde de l’imagination accessible par-delà les lettres écrites, et explore au contraire l’écriture automatique ou le pouvoir de signifiants qui font obstacle à l’intentionnalité de l’acte d’écriture. Mais un auteur qui ne se reconnaît plus dans ce qu’il écrit est-il encore un auteur ? Si à l’âge classique folie et littérature s’excluaient, le xxe siècle est le siècle d’une écriture qui s’écrit toute seule, et qui à ce titre échappe à l’exigence du sens pour devenir un simple jeu de symboles, c’est-à-dire un code qui ne peut se déchiffrer qu’a posteriori. Pour Friedrich Kittler, l’auteur est une fonction de son environnement média-technique et celui de 1900 est façonné par l’apparition du phonographe, qui enregistre ce que l’écriture échouait à dire (les bruits), du cinéma qui convoque l’imaginaire en agissant directement sur le système nerveux et de la machine à écrire qui permet d’écrire plus vite que l’on ne pense. Si tout s’écrit, que faut-il lire et comment ? Le tournant du xixe siècle est aussi l’époque en Europe d’une réforme pédagogique qui encourage les libres essais des élèves et non plus la lecture des auteurs classiques. La « mort de l’auteur », énoncée par Roland Barthes et Michel Foucault, est ainsi en réalité pour Friedrich Kittler celle de l’auteur de ce qu’il appelle le système d’inscription 1800, c’est-à-dire le réseau institutionnel et technique déterminant les modalités selon lesquelles les données peuvent être, à cette époque, adressées, stockées et traitées. Ce qui disparaît est le monopole d’une conception herméneutique de la lecture qui faisait d’un monde d’idées universelles le fondement et l’horizon de la littérature et de la lecture, pour laisser place aux matérialités de l’écriture et à une prise en compte renouvelée de la visualité de la page graphique.
Nomenclatural novelties for the Euro+Med flora
Authors: Banfi Enrico , Galasso Gabriele , Bartolucci Fabrizio
Published: December 2017

Today’s plant phylogeny more and more deals with ranks from the genus down, so changes in current taxonomy and nomenclature are frequently requested. For this reason, referring to the Euro+Med flora, we take here into account 20 taxa and recover the following forgotten nomenclatural combinations: Bidens atrosanguinea (Hook.) Regel, B. formosa (Bonato) Sch.Bip., B. sulphurea (Cav.) Sch.Bip., and B. tinctoria (Nutt.) Baill. ex Daydon. Moreover we propose the new names Agrostis linkii Banfi, Galasso and Bartolucci, Bidens selenactis Banfi, Galasso and Bartolucci, Bidens sweetiana Banfi, Galasso and Bartolucci, and the new combinations Achnatherum paradoxum (L.) Banfi, Galasso and Bartolucci, A. virescens (Trin.) Banfi, Galasso and Bartolucci, Agrostis linkii Banfi, Galasso and Bartolucci subsp. prostrata (Hack. and Lange) Banfi, Galasso and Bartolucci, Bidens atkinsoniana (Douglas ex Lindl.) Banfi, Galasso and Bartolucci, B. basalis (A.Dietr.) Banfi, Galasso and Bartolucci, B. gladiata (Walter) Banfi, Galasso and Bartolucci, B. lanceolata (L.) Banfi, Galasso and Bartolucci, Calamagrostis arenaria (L.) Roth subsp. arundinacea (Husn.) Banfi, Galasso and Bartolucci, Prunus ×hybrida (Schmidt) Galasso, Banfi and Bartolucci, Solanum aethiopicum L. subsp. anguivi (Lam.) Banfi, Galasso and Bartolucci, S. macrocarpon L. subsp. dasyphyllum (Schumach. and Thonn.) Banfi, Galasso and Bartolucci, S. melongena L. subsp. insanum (L.) Banfi, Galasso and Bartolucci, and Trisetaria argentea (Willd.) Banfi, Galasso and Soldano.
Demyelinating syndrome in SLE: review of different disease subtypes and report of a case series
Authors: Chessa E. , Piga M. , Floris A. , Mathieu A. , Cauli A.
Published: December 2017

Demyelinating syndrome (DS) is a rare manifestation of systemic lupus erythematosus (SLE) (1%) with high clinical heterogeneity and potentially severe prognosis. It can represent a diagnostic and therapeutic challenge for clinicians. A recent study described 5 different patterns of demyelinating disease presentation, characterised by specific clinical, laboratory and brain and spine magnetic resonance imaging abnormalities: 1) neuromyelitis optica; 2) neuromyelitis optica spectrum disorders; 3) DS prevalently involving the brain; 4) DS prevalently involving the brainstem; 5) clinically isolated syndrome. In this review we briefly discuss typical characteristics of each DS presentation in SLE and we describe 5 illustrative clinical cases, one for each subset of DS, considering both diagnostic and therapeutic options.
Plantar pain is not always fasciitis
Authors: Romano N. , Fischetti A. , Prono V. , Migone S. , Barbieri F. , Pizzorni C. , Garlaschi G. , Cimmino M.A.
Published: December 2017

The case is described of a patient with chronic plantar pain, diagnosed as fasciitis, which was not improved by conventional treatment. Magnetic resonance imaging revealed flexor hallucis longus tenosynovitis, which improved after local glucocorticoid injection.
G-Protein Inwardly Rectifying Potassium Channel 1 (GIRK1) Knockdown Decreases Beta-Adrenergic, MAP Kinase and Akt Signaling in the MDA-MB-453 Breast Cancer Cell Line
Authors: Hance Michael W. , Dhar Madhu S. , Plummer Howard K.
Published: December 2017

Previous data from our laboratory have indicated that there is a functional link between the beta-adrenergic receptor signaling pathway and the G-protein inwardly rectifying potassium channel (GIRK1) in breast cancer cell lines and that these pathways are involved in growth regulation of these cells. To determine functionality, MDA-MB-453 breast cancer cells were stimulated with ethanol, known to open GIRK channels. Decreased GIRK1 protein levels were seen after treatment with 0.12% ethanol. In addition, serum-free media completely inhibited GIRK1 protein expression. This data indicates that there are functional GIRK channels in breast cancer cells and that these channels are involved in cellular signaling. In the present research, to further define the signaling pathways involved, we performed RNA interference (siRNA) studies. Three stealth siRNA constructs were made starting at bases 1104, 1315, and 1490 of the GIRK1 sequence. These constructs were transfected into MDA-MB-453 cells, and both RNA and protein were isolated. GIRK1, β2-adrenergic and 18S control levels were determined using real-time PCR 24 hours after transfection. All three constructs decreased GIRK1 mRNA levels. However, β2 mRNA levels were unchanged by the GIRK1 knockdown. GIRK1 protein levels were also reduced by the knockdown, and this knockdown led to decreases in beta-adrenergic, MAP kinase and Akt signaling.
JUSTIÇA ESPACIAL E CIDADE DIGITAL: ESPAÇO COMO MEIO OPERACIONAL NO BRASIL
Authors: Serpa Angelo
Published: December 2017

Busca-se, com o presente artigo, construir uma abordagem comparativa da inserção de tecnologias de informação e comunicação no território nacional, em diferentes escalas (macrorregional, estadual e intra-urbana), pensando o espaço como “meio operacional” e tomando as noções de justiça espacial e acessibilidade como princípios norteadores da reflexão proposta. A discussão está também baseada na assertiva de que os lugares são “plataformas” para a construção de ações e discursos de cunho eminentemente espacial que atravessam variados recortes e escalas.Palavras-chave: Justiça espacial, cidade digital, espaço, meio operacional.
TERRITÓRIO E DESENVOLVIMENTO NA PERSPECTIVA DOS GEÓGRAFOS DA ESCOLA DE TURIM – ITÁLIA
Authors: Andrade Viana de Andrade Áurea , Serra Elpídio
Published: December 2017

O artigo discute os paradigmas de território e de desenvolvimento local dentro do Sistema Local Territorial (SLOT), pautado nos postulados dos geógrafos italianos. Através deste, buscamos demonstrar o debate acerca dessas questões, considerando as concepções teóricas e metodológicas da Escola de Turim de Geografia, especialmente dos geógrafos Giuseppe Dematteis, Francesca Governa, Egídio Dansero, Marco Baggiani, visto que se destacam nas produções científicas, desde a década de 1960, e têm influenciado o pensamento de pesquisadores brasileiros, que buscam uma abordagem relacional e híbrida, com as relações geográficas e com as articulações territoriais para o desenvolvimento.Palavras-chave: Território, desenvolvimento local, escola de Turim.
Concepts and Roles of Faculty in the Palestinian Universities in the Light of Knowledge Economy
Authors: Hasan Awajneh Ahlam Mustafa , Mohammed Sabbah Suhair Sulaiman , Saleh Naser Inas Aref
Published: December 2017

The study aims to recognizing the concepts of knowledge economy and the roles of faculty members in the light ofknowledge economy from the perspectives of its members, it was clear that the concept of the knowledge economywas high, it was (2.7,) and there were differences in years of experience in favor of (1-5 years) class, and in favor ofthe associate teacher in the educational degree, and the university in favor of Bier Ziet University. Whereas the meanof the faculty members’ roles was (2.26) with differences in gender in favor of the females and as for the university,in was in favor of Bier Ziet University.
Physicochemical Properties, Total Phenolic and Antioxidant Activity of Mixed Tropical Fruit Juice, TP 3 in 1TM
Authors: Abdul Malek Siti Nur Aqilah , Haron Hasnah , Wan Mustafa Wan Aida , Shahar Suzana
Published: December 2017

This study was carried out on the TP 3 in 1TM juice formulation, which consisted of pomegranate concentrate with guava and roselle extract. This study aimed to determine its physicochemical properties, proximate content, total phenolic content, antioxidant activity, total sugar, vitamin C and several targeted polyphenol compounds. Total phenol content was determined using Folin-Ciocalteu method while antioxidant activity was determined using DPPH and ABTS methods. The results showed pH and total soluble solid values of the juice were 3.69 and 8.1 °Brix, respectively. The juice has brightness colour of L = 33.25, a = 3.16 and b = -4.63. Every 100 ml juice contained 10.92 g total sugar, 4 mg vitamin C and 0.44% titratable citric acid. Proximate analyses showed TP 3 in 1TM juice contained 89.38% moisture, 0.15% total ash, 0.16% protein, 0% fat and 10.31% total carbohydrates. The juice was low in calories (42 kcal/100 ml) and contained total phenolic (609 mg GAE/100 ml) and total monomeric anthocyanin (12.94 mg C3G/100 ml). Antioxidant value obtained through DPPH and ABTS test methods were 88.90% and 472.44 µM TE/ml, respectively. Eight selected individual polyphenol compounds ranged from 0.13-633.73 mg/100 ml have been identified. TP 3 in 1TM juice consisting three different tropical fruits can be considered of having high phenolic content and antioxidant activity. Consumption of mixed tropical juices with various polyphenol compositions will protect human body from several diseases attributed to the reactions of free radicals.
O PROBLEMA DAS METÁFORAS NA CLÍNICA
Authors: Almeida Bruno Vasconcelos de , Nova Cruz Denise Viuniski da , Mostafa Solange Puntel
Published: December 2017

Este artigo problematiza o uso das metáforas na clínica médica e no ensino da clínica, extrapolando a questão para outros encontros terapêuticos, e destacando a importância da linguagem para as práticas de cuidado em saúde.  Para isso, apresenta dois argumentos teóricos diferentes a respeito da metáfora, figura de linguagem tão significativa para diferentes áreas de conhecimento: argumentos contrários à utilização das metáforas resgatados do texto clássico de Susan Sontag – Doença como Metáfora. AIDS e suas Metáforas, e uma teorização poética favorável às metáforas como forma de expressão e representação de sentimentos de dor e de perda no pensamento de Anatole Broyard – Intoxicated by my Illness and Other Writings on Life and Death. Esses dois resgates teóricos são utilizados para demonstrar a relevância do problema para a prática da clínica.  O artigo concentra-se na questão linguística e na literalidade no pensamento de Gilles Deleuze, alçando as metáforas ao domínio dos conceitos filosóficos.
Application of Google-based Data for Travel Time Analysis: Kaunas City Case Study
Authors: Dumbliauskas Vytautas , Grigonis Vytautas , Barauskas Andrius
Published: December 2017

Recently, new traffic data sources have emerged raising new challenges and opportunities when applying novel methodologies. The purpose of this research is to analyse car travel time data collected from smartphones by Google Company. Geographic information system (GIS) tools and Python programming language were employed in this study to establish the initial framework as well as to automatically extract, analyse, and visualize data. The analysis resulted in the calculation of travel time fluctuation during the day, calculation of travel time variability and estimation of origin-destination (OD) skim matrices. Furthermore, we accomplished the accessibility analysis and provided recommendations for further research.
Control of Luminescence by Tuning of Crystal Symmetry and Local Structure in Mn4+‐Activated Narrow Band Fluoride Phosphors
Authors: Fang Mu‐Huai , Wu Wei‐Lun , Jin Ye , Lesniewski Tadeusz , Mahlik Sebastian , Grinberg Marek , Brik Mikhail G. , Srivastava Alok M. , Chiang Chang‐Yang , Zhou Wuzong , Jeong Donghyuk , Kim Sun Hee , Leniec Grzegorz , Kaczmarek Slawomir M. , Sheu Hwo‐Shuenn , Liu Ru‐Shi
Published: December 2017

Mn4+‐doped fluoride phosphors have been widely used in wide‐gamut backlighting devices because of their extremely narrow emission band. Solid solutions of Na2(SixGe1−x)F6:Mn4+ and Na2(GeyTi1−y)F6:Mn4+ were successfully synthesized to elucidate the behavior of the zero‐phonon line (ZPL) in different structures. The ratio between ZPL and the highest emission intensity υ6 phonon sideband exhibits a strong relationship with luminescent decay rate. First‐principles calculations are conducted to model the variation in the structural and electronic properties of the prepared solid solutions as a function of the composition. To compensate for the limitations of the Rietveld refinement, electron paramagnetic resonance and high‐resolution steady‐state emission spectra are used to confirm the diverse local environment for Mn4+ in the structure. Finally, the spectral luminous efficacy of radiation (LER) is used to reveal the important role of ZPL in practical applications.
The Role of Mg(OH)2 in the So‐Called “Base‐Free” Oxidation of Glycerol with AuPd Catalysts
Authors: Fu Jile , He Qian , Miedziak Peter J. , Brett Gemma L. , Huang Xiaoyang , Pattisson Samuel , Douthwaite Mark , Hutchings Graham J.
Published: December 2017

Mg(OH)2‐ and Mg(OH)2‐containing materials can provide excellent performance as supports for AuPd nanoparticles for the oxidation of glycerol in the absence of base, which is considered to be a result of additional basic sites on the surface of the support. However, its influence on the reaction solution is not generally discussed. In this paper, we examine the relationship between the basic Mg(OH)2 support and AuPd nanoparticles in detail using four types of catalyst. For these reactions, the physical interaction between Mg(OH)2 and AuPd was adjusted. It was found that the activity of the AuPd nanoparticles increased with the amount of Mg(OH)2 added under base‐free conditions, regardless of its interaction with the noble metals. In order to investigate how Mg(OH)2 affected the glycerol oxidation, detailed information about the performance of AuPd/Mg(OH)2, physically mixed (AuPd/C+Mg(OH)2) and (AuPd/C+NaHCO3) was obtained and compared. Furthermore, NaOH and Mg(OH)2 were added during the reaction using AuPd/C. All these results indicate that the distinctive and outstanding performance of Mg(OH)2 supported catalysts in base‐free condition is in fact directly related to its ability to affect the pH during the reaction and as such, assists with the initial activation of the primary alcohol, which is considered to be the rate determining step in the reaction.