bluuebunny/crossref_metadata_2025 huggingface dataset:
Development of evidence-based guidelines for the treatment and management of periprosthetic hip infection
Authors: Moore Andrew J. , Wylde Vikki , Whitehouse Michael R. , Beswick Andrew D. , Walsh Nicola E. , Jameson Catherine , Blom Ashley W.
Published: April 2023

Aims

Periprosthetic hip-joint infection is a multifaceted and highly detrimental outcome for patients and clinicians. The incidence of prosthetic joint infection reported within two years of primary hip arthroplasty ranges from 0.8% to 2.1%. Costs of treatment are over five-times greater in people with periprosthetic hip joint infection than in those with no infection. Currently, there are no national evidence-based guidelines for treatment and management of this condition to guide clinical practice or to inform clinical study design. The aim of this study is to develop guidelines based on evidence from the six-year INFection and ORthopaedic Management (INFORM) research programme.

Methods

We used a consensus process consisting of an evidence review to generate items for the guidelines and online consensus questionnaire and virtual face-to-face consensus meeting to draft the guidelines.

Results

The consensus panel comprised 21 clinical experts in orthopaedics, primary care, rehabilitation, and healthcare commissioning. The final output from the consensus process was a 14-item guideline. The guidelines make recommendations regarding increased vigilance and monitoring of those at increased risk of infection; diagnosis including strategies to ensure the early recognition of prosthetic infection and referral to orthopaedic teams; treatment, including early use of DAIR and revision strategies; and postoperative management including appropriate physical and psychological support and antibiotic strategies.

Conclusion

We believe the implementation of the INFORM guidelines will inform treatment protocols and clinical pathways to improve the treatment and management of periprosthetic hip infection.

Cite this article: Bone Jt Open 2023;4(4):226–233.
Future changes of snow-related variables in different European regions
Authors: Kis Anna , Pongrácz Rita
Published: April 2023

Snow has an important role in the climate system and also has environmental, natural and socio-economic impacts. Temperature, precipitation, snow coverage, snow depth and snowmelt are analysed in this study for 1971–2099 based on EURO-CORDEX simulations. In order to measure uncertainty, three different scenarios (RCP2.6, RCP4.5, RCP8.5) and five different regional climate models are taken into account. The investigation focuses on eight regions, characterised by different climatic conditions (maritime, continental, boreal). Relative changes of the selected parameters are calculated for 2021–2050 and 2069–2098 compared to 1971–2000 reference period, in addition to the evaluation of the simulated reference. The relative role of the three main uncertainty factors (internal climatic variability, model selection, and used scenario) is also analysed. According to our results, model selection and internal variability possess the most important roles. Based on the multi-model mean, annual mean temperature and precipitation total will increase, the snow cover period will become shorter (the higher the radiative forcing change in the scenario, the greater the decrease), and the snowmelt process is likely to occur earlier in the northern region. Thus, the warming trend seems to have a greater effect on the snow-related variables than increasing precipitation trends. These projected changes may have a huge impact on winter tourism and sports, hence, appropriate adaptation strategies will be crucial.
Kunc, J., Križan, F., Novotná, M., Bilková, K., Sikos, T.T., Ilnicki, D. and Wyeth, R.: Thirty Years of Retail Transformation in V4 Countries
Authors: Szendi Dóra
Published: April 2023

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Assessment of Taungya agroforestry system in dryland forests rehabilitation in Sudan
Authors: Hemida Mohamed , Yasin Emad H E , Kheiry Manal A , Hammad Zeinab M , Vityi Andrea
Published: April 2023

The decline of the forest cover due to deforestation and agricultural expansion in Sudan has reached a critical situation. Taungya agroforestry systems have been used as a strategy to safeguard against this process, allowing farmers to cultivate their subsistence crops at the early stage of tree plantations. The current study research tackled Nabag Forest Reserve (NFR) as a case study to assess and explore Taungya agroforestry system as a practice used for forest rehabilitation in the study area. Satellite images of Landsat 5 Thematic Mapper, and Landsat 8 Operational Land Imager/Thermal Infrared Sensor of 1991, 2001, 2011, and 2021 were used to generate forest cover maps. Both unsupervised and supervised classification, as well as ground truth points, were applied to classify the vegetation cover in NFR as dense forest (DF), light forest (LF), agricultural field (AF), and bare land (BL). The results showed that two trends of forest cover changes occurred in NFR between 1991-2001 and 2011-2021. It was well explored that through Taungya agroforestry, there was a considerable increase in forest cover over this period. This could be clearly detected by increasing dense forest and light forest cover by 1041.73 ha (24.95%) and 2.95 ha (0.07%), respectively and decreasing of bare land and agricultural field by 409.79 ha (9.81%) and 634.52 ha (15.15%) during the addressed period. The findings of the study indicated that Taungya agroforestry system could be a feasible land-use alternative for forest recovery in the dry land of Sudan.
Growth and Yield of Kale, Swiss chard, Amaranth, and Arugula microgreens in response to different growing medium substrates
Authors: Saleh Roksana , Gunupuru Lokanadha Rao , Abbey Lord
Published: April 2023

Microgreens are relatively novel food with high nutrition and dietary benefits that can be influenced by the growing medium. Two experiments were performed to develop an optimum media for microgreensfrom kale (Brassica oleracea L. var. acephala), Swiss chard (Betavulgaris var. cicla), arugula (Eruca vesicaria ssp. sativa), and amaranth (Amaranthus tricolour L.). Experiment 1 was screening of media T1 = 30% vermicast + 40% sawdust + 30% perlite; T2 = 30% vermicast + 50% sawdust + 20% perlite; T3 = 50% vermicast + 30% sawdust + 20% perlite; T4 = 30% vermicast + 40% sawdust + 30% mushroom compost; T5 = 30% vermicast + 20% sawdust + 20% perlite + 30% mushroom compost; and a negative control (NC) = 50% sawdust + 50% mushroom compost. The positive control was Promix BX™ potting mix alone. Experiment 2 was to test the efficacy of two different sources of mushroom compost (White oyster mushroom compost (MC1) and Shiitake mushroom compost (MC2)) added to media T1 to T5 above. The results showed that the media physicochemical properties varied across treatments. Higher chemical parameters were obtained for T4, T5, and media containing MC1. Porosity and water retention were increased in media containing MC2 compared to the other.Seed germination, plant height, and microgreen yield were statistically (P>0.05) enhanced by T2 and T4 that contained MC2 compared to the rest. Microgreens yield was approximately three times higher in T2 and 4 with added MC2, except the yield of arugula which was two times higher in these media compared to the control. Overall, T5 alone, and T2 and T4 with added MC2 were the most effective media for microgreen production. Future studies will assess microgreens’ nutrients in different media.
Ethnobotanical Plants of Phumdi, Loktak Lake, Manipur, India
Authors: Devi Rajkumari Supriya , Satapathy Kunja Bihari , Kumar Sanjeet
Published: April 2023

Loktak is the largest natural freshwater lake in the North-Eastern region of India playing an important role in the ecological and economic security of the region. It is also known for “Phumdi,” a heterogeneous mass of soil, vegetation and organic matter at various stages of decomposition. For the fishing purposes, local communities make a ring with “Phumdi” mass called “Athaphum” measuring 500 ft in diameter, a traditional practice popular since last 200 years. It is further interesting to report that these also harbor a rich flora of medicinal herbs. Keeping the importance of its medicinal wealth, an attempt was made to survey 20 different “Athaphum” of the lake to explore and document the diversity of medicinal plants of the fresh water lake. Extensive floristic survey in the study area revealed the occurrence of over 89 plant species in and around “Athaphum” and “Phumdis.” Among them, five plants (Blumea mollis, Ludwigia repens, Rumex nepalensis, Oenanthe javanica, and Carex riparia) were selected for phytochemical screening to validate their therapeutic claims. All the selected plants were found to be enriched with phenolic compounds. On the basis of their ethnobotanical claims and results of phytochemical analysis, R. nepalensis and O. javanica could be recommended as potential nutraceutical for being a popular food plant among the local inhabitants.
An Improved Ant Colony Optimization Algorithm for Vehicle Routing Problem with Time Windows
Authors: Ibrahim Muhammad Faisal , Mustofa M. I. , Meilanitasari P , Wijaya S. U.
Published: April 2023

Distribution plays an important role in the supply chain system. One of the critical problems in distribution is the vehicle routing problem. This research proposes the Improved Ant Colony Optimization (IACO) algorithm to solve the Vehicle Routing Problem with Time Windows (VRPTW). The main objective is to minimize the total vehicle mileage by considering the vehicle capacity and customer time windows. The proposed IACO algorithm is inspired by the conventional Ant Colony Optimization (ACO) algorithm by adding local search and mutation processes. Numerical experiments were conducted to test that the routes generated did not violate the customer's time window constraints. In addition, this study also compares the proposed IACO algorithm routes with other metaheuristic algorithms, namely ACO classic and Tabu Search. In addition, this investigation was carried out by experimenting with the number of iterations. The results of numerical experiments prove that the proposed IACO algorithm can minimize the total vehicle mileage without violating capacity constraints and time windows.
Implementation of the Merdeka Curriculum Using Citizen Science Project Weather-it to Improve Critical Thinking Skills of Junior High School Students
Authors: Muaziyah St E Sururiyatul , Hidayat Topik , Sriyati Siti , Lutianasari Lia
Published: April 2023

The Merdeka curriculum requires teachers and educational units to provide project activities in student learning. The project activities aim to improve students' skills, one of which is critical thinking. This study aims to see the feasibility of the citizen science project, Weather-it, as part of project activities in the Merdeka curriculum to improve students' critical thinking skills. This study uses the Pre-experimental method with the One-Group Pretest-Posttest Design. A total of 42 grade 7 students at a junior high school in Bandung took part in the citizen science project, Weather-it. The validated pre-test and post-test questions were made and used to analyze the improvement of students' critical thinking skills. This increase can be seen from changes in the average pre-test and post-test scores and by calculating the N-Gain score. The results showed an increase in the average value of students' critical thinking, from 48.75 (pre-test) to 70.41 (post-test). The N-Gain score states the effectiveness of the citizen science project, Weather-it, where 57.1% of students are in the medium category, 28.6% in the high category and 14.3% in the low category. Likewise, the results reflect how the citizen science project, Weather-it, can be implemented as part of implementing the Merdeka curriculum
Development of Web-Based Learning Media (Glideapps) to Improve Digital Literacy and Science Literacy About Materials Human Digestive Systems
Authors: Aprilia Charolin , Anggereini Evita , Nazarudin Nazarudin , Ahda Yuni
Published: April 2023

Learning media is part of learning that contains messages, people, and devices, which follow technological developments. This study aims to determine the feasibility of developing web-based learning media to improve digital and scientific literacy skills in the material of the human digestive system in class VIII J at SMP Negeri 11 Jambi City. This research development uses the Dick & Carey development model. The test subjects consisted of a small group of 6 people and a large group consisting of 33 students who were students of SMP Negeri 11 Kota Jambi. The instruments used in this study were interviews, questionnaires, tests and validation assessment sheets. This study uses a one-shot case study experimental design. The data analysis technique used in this research is descriptive research with a quantitative approach. The results of this study are media validation. The first material validation gets a score of 56%, and the classification of eligibility is not good with several improvements. The second gets a score of 72%, the classification of eligibility is good, and the third gets a score of 91%, the classification is very good. The first media validation gets a score of 50%, and the feasibility classification is not good with several improvements. The second gets a score of 72%, the feasibility classification is good, and the third gets a score of 94%, and the classification is very good. The effectiveness of web-based learning media (glideapps) in increasing digital literacy was carried out in large group tests obtaining an average value of 0.4915 or 49.1465% with a moderate level of effectiveness. The effectiveness of web-based learning media (glideapps) in increasing digital literacy is carried out in large group tests obtaining an average value of 0.4464 or 44.6496% with a moderate level of effectiveness.
Feasibility Analysis of Thermochemistry Senior High School Chemistry Textbook Based on Criteria of Four Steps Teaching Material Development Method
Authors: Anwar Sjaeful , Sumarna Omay , Mulyadi Andi
Published: April 2023

This study was conducted to analysis properness of thermochemistry teaching material in chemistry school textbook which is used in most SMA/MA in Kota Bandung based on criteria of selection stage of Four Steps Teaching Material Development (4STMD) method. The type of research is evaluative research by content analysis method. There are three criteria in the selection process of 4STMD method. First is conformity with the curriculum, it is known that object of research is not yet fully in accordance with the demands of the Curriculum. In terms of material broadness, there are four concepts required by the curriculum that are not included in the teaching material, so that the teaching material is less broad. In addition, there are six concepts that are not required by the curriculum, but included in the material, so that the material is too broad. Thus, in general, the material broadness is not in accordance with the demands of the Curriculum. Meanwhile, in terms of concepts depth, from 31 concepts demanded by the curriculum, 18 concepts are less deep and three concepts are too deep. Based on second criteria, that is scientific correctness of the concepts, it is known that there are two concepts that are not scientifically correct according to references from international general chemistry textbooks and books published by IUPAC. Based on the third criterion, namely the cultivation of pedagogical context, it is known that the values and skill embedded in the material are religious values, creativity, curiosity, respect for achievement, responsibility, reading-interested, discipline, and environmental care
Analysis of Computational Thinking Instrument for High School Student Using Rasch Model
Authors: Sulsilah Hani , Hidayat Arif , Ramalis Taufik Ramlan
Published: April 2023

This study is aimed-to construct and analyze the Computational Thinking Instrument at Physics subject using Rasch Measurement Model. The instrument was developed by the researcher to assess students’ computational thinking in Grade Eleventh in high school on heat and transfer topics under STEM Quartet Integrated Learning. The type of the instrument is a multiple choice with multiple-choice reasoning. This test consists of 13 questions to measure five concepts of Computational Thinking which are abstraction, decomposition, algorithm, evaluation, and generalization. The test was tried out on 120 students (87 female and 33 male aged 16-18 years old) in West Java and Banten. The item of the questions on the test was analyzed using Winstep 5.3.2.0. The reliability of the Instrument can be shown at the Cronbach’s alpha, Item Reliability, Person Reliability, Item Separation, and Person Separation. The result shows that Cronbach’s alpha (KR-20) is 0.75 which means the instrument has high reliability. The value of the item reliability is 0.95 and person reliability is 0.72. This means that although the consistency of student in answering questions is sufficient, the instrument has high reliability. The values of the item and person separation are 1.61 and 4.43 which means that the instrument has great separation. The validity of the instrument can be seen in unidimensionality and item fit order. The unidimensionality shows that the value of Raw Variance Explain by Measure is 32.8%, the Unexplained variance 1-5 contrast is below 15% and the eigenvalues are also below 3%. Overall, 8 of 13 items of the test meet 3 criteria of the item fit order, then 5 items have 2 of 3 criteria of the item fit order. We can conclude that this Instrument is reliable and valid. Then, the instrument can be used to measure students’ computational thinking on heat and transfer topics
Effect of Argumentation-Based Teaching on Students’ Understanding, Reasoning and Decision-Making Concerning Food Preservatives
Authors: Widodo Ari , Huda Intania Zainul Nurul , Rochintaniawati Diana , Riandi Riandi
Published: April 2023

Misuse of food preservatives in the society is alarming that it is necessary to raise students’ awareness about the danger to their health. Educating children about healthy food requires more than just promoting understanding but more importantly practicing reasoning and decision making. This study analyses the impact of lessons designed to improve students’ understanding, reasoning, and decision making on the use of food preservatives. Participants of the study were 30 students of 7th grade junior high school taught by a teacher who has been trained on argumentation-based teaching strategies. During the lessons students were provided with dilemmatic cases that stimulate their thinking followed by discussion before finally making a decision. Data were collected prior and after the lessons using a three-tier test that require students to provide answers that consist of explanation, reason, and evidence. The study shows improvement of students’ understanding of the content, reasoning skills, and decision making. Moreover, the study also reveals that the majority of the students tend to view food preservatives from the usefulness side but ignore the danger. The findings suggest that argumentation-based teaching strategy results in students’ deeper understanding of the content, reasoning and decision-making skills. This study recommends that efforts to promote students’ awareness of food preservatives and healthy diet can be done through a systematic and well-planned teaching strategy that encourage students to reason and to think deeply about the positive and the negative sides of food preservatives
Comparison of Chemical and Biological Control Techniques to Stem Rot Fusarium Spp. On Fig Seedlings (Ficus Carica L.) as an Effort to Substitute Agrochemical Inputs in Environmentally Friendly Control
Authors: Hadi Pramono , Rachmawatie Srie Juli , Masnur Moh.
Published: April 2023

Figs have many benefits to treat various health problems, so it is necessary to breed vegetatively so that the production of figs can increase in the future. Fig nurseries have problems with the success of seedlings caused by stem rot disease due to the attack of pathogen Fusarium spp. This study aims to determine the ability of chemical and biological control techniques in suppressing the intensity of stem rot disease caused by pathogen Fusarium spp., as well as looking for substitution of agrochemical inputs for environmentally friendly disease control. The research was conducted at greenhouse faculty of agriculture, Batik Islamic University of Surakarta, from September 15, 2020 to December 23, 2020. The study used a Complete Randomized Design (RAL), with 6 types of control technique treatments, consisting of control, biological Trichoderma spp., biological Gliocladium spp., biological Corynebacterium spp., biological PGPR, and chemical Mankozeb, which was repeated 3 times and 3 times subrepannant. Observation consists of the parameters of the incubation period of the disease, the incidence of the disease, and the severity of the disease. The results showed that the treatment of biological control techniques was able to reduce the intensity of disease attacks with the best results obtained in trichoderma spp biological control agents (APH). which is able to delay the incubation period of the disease up to 48.89hsi, reduce the incidence of the disease by 88.89%, and reduce the severity of the disease by up to 97.78% because it has antagonism abilities in the form of competition mechanisms, mycoparasites, and antibiosis. Ability APH Trichoderma spp. can be an alternative solution to substitute agrochemical inputs in disease control that is more environmentally friendly and sustainable and can maintain natural balance in agroecosystems
Role of Carrier Media and Types of Indigenous MVA Isolates on Soil Quality in Corn Plants in the Dry Land of West Nusa Tenggara
Authors: Sukmawati Sukmawati , Adnyana I Made , Supraptha Dewa Ngurah , Busaifi Riski
Published: April 2023

Corn plants have many benefits and are needed by the government as a national food reserve. West Nusa Tenggara (NTB) maize production fluctuated. If managed optimally, dry land agriculture in NTB can provide benefits for increasing agricultural production, especially corn production. The sustainability of dry land farming systems must be continuously improved even with various farming strategies with the main objective of improving soil fertility and overcoming drought stress constraints. One of the efforts to increase the productivity of NTB's dry land is the use of arbuscular vesicular mycorrhizal biofertilizers which are an alternative to improve the quality of soil and plants. Arbuscular vesicular mycorrhiza will colonize and infect roots maximally if using a carrier media that is compatible with MVA inoculant. Appropriate MVA carrier media will provide optimal environmental conditions for host plant growth. The aim of the research was to determine the role of Indigenous MVA and carrier media on soil quality in dryland maize. The research was carried out on corn plants using different carrier media and native MVA types. The study was designed as a factorial study using a completely randomized design (CRD) with 2 factors, namely the type of indigenous MVA isolates with 3 treatment levels and the Carrier Media Type factor with 4 treatment levels. There were 12 treatment combinations that were repeated 3 times so that 36 treatment combinations were obtained which were carried out at the Green House of the Faculty of Agriculture, Nahdhatul Wathan University, Mataram from December 2020 to February 2021. The results showed that the MVA type factor, the MVA isolate had a significantly different effect for all observation parameters, namely soil water content, soil pH, soil total N content and soil available P content, the best isolate was Glomus sp. The carrier media factor gives the result that the type of carrier media has a significant effect on the parameters of observing soil water content, soil total N content and soil pH with the best carrier media being rice husk charcoal biochart
Bridging Phenomenology and Neural Mechanisms of Inner Speech: ALE Meta-Analysis on Egocentricity and Intentionality in a Dual-Mechanistic Framework
Authors: Pratts Jaydan , Pobric Gorana , Yao Bo
Published: April 2023

The neural mechanisms of inner speech remain unclear despite its importance in a variety of cognitive processes and its implication in aberrant perceptions such as auditory verbal hallucinations. Previous research has proposed a corollary discharge model in which inner speech is a truncated form of overt speech, relying on speech production-related regions (e.g. left inferior frontal gyrus). This model does not fully capture the diverse phenomenology of inner speech and recent research suggesting alternative perception-related mechanisms of generation. Therefore, we present and test a framework in which inner speech can be generated by two separate mechanisms, depending on its phenomenological qualities: a corollary discharge mechanism relying on speech production regions and a perceptual simulation mechanism within speech perceptual regions. The results of the activation likelihood estimation meta-analysis examining inner speech studies support the idea that varieties of innerspeech recruit different neural mechanisms.
Impact of insurance status on healthcare resource utilization and outcomes in adolescent patients presenting with spinal cord injuries
Authors: Sandhu Mani Ratnesh S. , David Wyatt B. , Reeves Benjamin C. , Sherman Josiah J. Z. , Craft Samuel , Jayaraj Christina , Boroumand Sam , Clappier Mona , Gutierrez Alan , Sarkozy Margot , Koo Andrew B. , Tuason Dominick A. , DiLuna Michael L. , Elsamadicy Aladine A.
Published: April 2023

OBJECTIVE

Insurance disparities have been suggested to influence the medical and surgical outcomes of adult patients with spinal cord injury (SCI), with a paucity of studies demonstrating their impact on the outcomes of pediatric and adolescent SCI patients. The aim of this study was to assess the impact of insurance status on healthcare utilization and outcomes in adolescent patients presenting with SCI.

METHODS

An administrative database study was performed using the 2017 admission year from 753 facilities using the National Trauma Data Bank. Adolescent patients (11–17 years old) with cervical/thoracic SCIs were identified using International Classification of Diseases, Tenth Revision, Clinical Modification coding. Patients were categorized by governmental insurance versus private insurance/self-pay. Patient demographics, comorbidities, imaging, procedures, hospital adverse events (AEs), and length of stay (LOS) data were collected. Multivariate regression analyses were used to determine the effect of insurance status on LOS, any imaging or procedure, or any AE.

RESULTS

Of the 488 patients identified, 220 (45.1%) held governmental insurance while 268 (54.9%) were privately insured. Age was similar between the cohorts (p = 0.616), with the governmental insurance cohort (GI cohort) having a significantly lower proportion of non-Hispanic White patients than the private insurance cohort (PI cohort) (GI: 43.2% vs PI: 72.4%, p < 0.001). While transportation accident was the most common mechanism of injury for both cohorts, assault was significantly greater in the GI cohort (GI: 21.8% vs PI: 3.0%, p < 0.001). A significantly greater proportion of patients in the PI cohort received any imaging (GI: 65.9% vs PI: 75.0%, p = 0.028), while there were no significant differences in procedures performed (p = 0.069) or hospital AEs (p = 0.386) between the cohorts. The median (IQR) LOS (p = 0.186) and discharge disposition (p = 0.302) were similar between the cohorts. On multivariate analysis, with respect to governmental insurance, private insurance was not independently associated with obtaining any imaging (OR 1.38, p = 0.139), undergoing any procedure (OR 1.09, p = 0.721), hospital AEs (OR 1.11, p = 0.709), or LOS (adjusted risk ratio −2.56, p = 0.203).

CONCLUSIONS

This study suggests that insurance status may not independently influence healthcare resource utilization and outcomes in adolescent patients presenting with SCIs. Further studies are needed to corroborate these findings.
Institutions’ Effect on a Country’s Investment Attractiveness within Sustainable Development
Authors: Moskalenko Bogdan , Lyulyov Oleksii , Pimonenko Tetyana , Kobushko Ihor
Published: April 2023

Sustainable development requires implementation of relevant green transformation of countries by providing green policies and extending green technologies and renewable energies. Withal, it requires attracting additional knowledge, human, financial, and natural resources. In this case, countries with higher investment attractiveness have a higher capability to attract additional knowledge and resources to implement mechanisms and policies to achieve sustainable development goals. The effectiveness of public governance is a basic condition for the successful modernization of the economy to develop a positive business climate and attract investment. The paper aims at analysing the impact of institutions’ quality on a country’s investment attractiveness. The objects of research are Ukraine and the EU countries. The study applies correlation and regression analysis to achieve the purpose of the research. The findings show that institutions’ quality has a positive and statistically significant effect on a country’s investment attractiveness in the EU countries. However, in political stability, freedom and quality of governance positively influence a country’s investment attractiveness. Improving political stability by one point promotes the integrated index of a country’s investment attractiveness for the EU country by 0.086 and for Ukraine by 0.016. The impact of the rule of law on a country’s investment attractiveness is not statistically significant. This means that Ukraine has not formed an appropriate and affordable legislation base for attracting investors to the country. Thus, the Ukrainian government should pay attention to legislation for the regulation of social and economic development and energy and resource use.
Recommendations on the use of azole antifungals in hematology-oncology patients
Authors: Azanza José Ramón , Mensa José , Barberán José , Vázquez Lourdes , Pérez de Oteyza Jaime , Kwon Mi , Yáñez Lucrecia , Aguado José María , Cubillo Gracian Antonio , Solano Carlos , Ruiz Camps Isabel , Fortún Jesús , Salavert Lletí Miguel , Gudiol Carlota , Olave Rubio Teresa , García-Vidal Carolina , Rovira Tarrats Montserrat , Suárez-Lledó Grande María , González-Sierra Pedro , Dueñas Gutiérrez Carlos
Published: April 2023

The administration of antifungals for therapeutic and, especially, prophylactic purposes is virtually a constant in patients requiring hematology-oncology treatment. Any attempt to prevent or treat Aspergillus or Mucor infections requires the administration of some drugs in the azole group, which include voriconazole, posaconazole and isavuconazole, noted for their activity against these pathogens. One very relevant aspect is the potential risk of interaction when associated with one of the antineoplastic drugs used to treat hematologic tumors, with serious complications. In this regard, acalabrutinib, bortezomib, bosutinib, carfilzomib, cyclophosphamide, cyclosporine A, dasatinib, duvelisib, gilteritinib, glasdegib, ibrutinib, imatinib, nilotinib, ponatinib, prednisone, ruxolitinib, tacrolimus, all-transretinoic acid, arsenic trioxide, venetoclax, or any of the vinca alkaloids, are very clear examples of risk, in some cases because their clearance is reduced and in others because of increased risk of QTc prolongation, which is particularly evident when the drug of choice is voriconazole or posaconazole.
Tezden Makale Üretmek: Ama Nasıl?
Authors: DEMİR Abdullah
Published: April 2023

Tezden makale üretmek, yüksek lisans ve doktora tezi tamamlanmadan önce veya sonra gündeme gelmektedir. Tez tamamlanmadan önce tez verisini kullanarak makale yayımlamak, tezin özgünlüğünü tartışmaya açabilir. Tez tamamlandıktan sonra yayın yapılması daha uygundur. Tezin tamamlanmasından sonra yapılan yayın, araştırmacının ve tezin bilinirliğini artırır. Bununla birlikte tezden yayın üretilirken tezden oluşturulduğunun belirtilmesi gereklidir. Ayrıca makale yazım sürecinde danışman önemli bir katkı sunmuşsa, ikinci yazar olarak belirtilmesi zorunludur. Tezden makale üretmek sadece kopyala-yapıştır işi değildir. Tezden makale üretmek tahmin edildiğinden daha zordur. Editörler ve hakemler aceleyle dönüştürülen bir makaleyi kolaylıkla fark ederler. Bu nedenle tez makaleye dönüştürülürken yoğun emek sarf edilmesi gerekir.
A Review of the Flood Hazard and Risk Management in The South Iran Region, Particularly Konarak, Makoran in Balochestan
Authors: Zainudini Mohammad Anwar , Sardarzaei Asadollah
Published: April 2023

Flood preparedness involves building capacities that enable minimizing losses through effective response and recovery. While there are many preparedness assessments at household and community level, very few have been conducted at institutional level. This study assessed the households' perspectives of the preparedness of civil protection institutions in Iran during the 2021 Balochestan flood disaster and identified the capacity building needs of the civil protection institutions. It used a 5-point Likert scale to measure six preparedness indicators: emergency plans, early warning systems, evacuation, resources, disaster knowledge, and relocation camp management. Data came from a cross-sectional survey involving 1456 household-heads who were randomly selected among the affected villagers of Konarak.The findings revealed various gaps in preparedness both at indicator and at variable level. While some indicators showed incipient levels of development in all their variables, others had a combination of low and developed variables. The preparedness elements that critically need immediate attention include the development of emergency plans, evacuation of populations at risk and the prepositioning of resources. However, it is pertinent to mention that civil protection Systems in Iran need to strengthen most of their preparedness elements. As such, this study recommends strengthening preparedness activities in civil protection systems.
Un échec démocratique ?
Authors: Baeckelandt Simon , Bonin Hugo
Published: April 2023

En 2021, le Conseil économique, social et environnemental (Cese) a formalisé la participation à ses travaux de citoyens tirés au sort. Aujourd’hui, des frustrations s’expriment. De quoi interroger la capacité du système représentatif à s’ouvrir à de nouveaux visages.
Grenoble fait ses gammes
Authors: Back Antoine , Guillou Benoît
Published: April 2023

La Ville de Grenoble s’essaie à l’indicateur du Donut dans le cadre de son plan « Grenoble 2040 ». L’objectif : mettre en place des politiques socio-environnementales soutenables. Entretien avec Antoine Back, adjoint au maire.
Ibest, indicateur de bien-être
Authors: Berthaud Annabelle
Published: April 2023

La rénovation des Villeneuves, menée par la Métropole de Grenoble, s’appuie sur un indicateur local centré sur le bien-être soutenable : l’Ibest. De quoi démontrer l’impact concret de ces nouvelles méthodes d’évaluation des politiques publiques.
Reflet d’un possible
Authors: Ferren Pascal , Guillou Benoît
Published: April 2023

Le Parlement de Loire, expérience unique en France, entend doter le fleuve d’une personnalité juridique. Le but : trouver une mécanique politique de la représentation des éléments naturels. Entretien avec Pascal Ferren, l’un des protagonistes de l’initiative.
Du pouvoir d’achat au pouvoir de vivre
Authors: Viveret Patrick
Published: April 2023

Plus ambitieux que le pouvoir d’achat, le pouvoir de vivre invite à repenser ce à quoi nous donnons de la valeur, en questionnant la place de la monnaie dans nos sociétés. Mais un tel bouleversement n’est pas sans risques et suppose le renforcement de l’exigence démocratique.
Le glaive chinois
Authors: Munier Jean-Charles
Published: April 2023

Dotées de propriétés physiques exceptionnelles, lesdites « terres rares » sont une ressource géologique cruciale pour nos économies et pour la transition énergétique. La Chine contrôle la majorité de la production. Ce quasi-monopole incite à envisager d’autres solutions.
Strategic HR Management Impacts on the Performance of an Organization
Authors:   Ph.D. Candidate, Faculty of Business, Karabuk University, Karabuk, Turkey, Doka Peace , Zehra TAN Pro. Dr. Fatma ,   Faculty of Business, Karabuk University, Karabuk, Turkey
Published: April 2023

Strategic HR management has an impact on the performance of an organization and it can play an effective role. SHRM constructs organizations’ desired objectives which are attainable and boost their performance. For that reason, this paper investigates the impact of strategic HR management on an organization’s performance and the correlations between them. Researchers have done some studies on strategic human resources management and explored how strategic H management influences the performance of an organization. However, studies claim that strategic HR management positively impacts the performance of an organization, job attitudes, and personal performance of HR professionals.
Library Services Amidst the COVID-19 Pandemic: Study of Remotely Exploitable Electronic Academic Databases in Selected University Libraries in Nigeria
Authors: Clifford Ishola Bolanle , Ojokuku Yemisi , Akpobasah-Amugen Sarah , Eluyemi Omotoyosi
Published: April 2023

The study adopted a research design of the qualitative type to investigate library services amid the COVID-19 Pandemic using remotely exploitable electronic academic databases in two Nigerian foremost university libraries, as case studies. An Interview guide was used to elicit data from E-Librarians of the two Federal University libraries randomly selected for the study. The interview guide contains seventeen questions that seek to proffer answers to the main objective of the study. Response retrieved were analyzed using thematic analysis to extract codes, identify patterns, and create themes relevant to the study’s objective. The study revealed that both libraries have a functional E-library and subscribes to key databases. The study also revealed that both libraries’ websites are connected to open source databases remotely accessible to library users. The study reinforces the need to embrace the change in the global architecture of library services in the wake of the COVID -19 pandemic and make their E-resources remotely accessible to users. The study recommended that library managers should adopt best practices in providing users with remote access to their E-resources. Also, the study underscores the need for library managers to reappraise their memorandum of understanding with E-databases aggregator, allowing their E-resources to be remotely accessible to library users’ thereby limiting users contact with their physical library environment amid the COVID-19 Pandemic.
ACHIEVING SUSTAINABLE BUSINESS PERFORMANCE THROUGH GREEN TRANSFORMATIONAL LEADERSHIP, GREEN INNOVATION & CORPORATE SOCIAL RESPONSIBILITY
Authors: Zain Fahad , Abbas Muhammad Zaigham , Ali Muhammad Rizwan
Published: April 2023

There are numerous approaches to sustainability; one of them is the notion of green economy. Society is more aware of business operations' environmental impact since industrial operations contribute to environmental imbalance. Small and medium enterprises (SMEs) act as a catalyst for the development of economy. The current study examines impact of green transformational leadership (GTL), green innovation (GI), and corporate social responsibility (CSR) on sustainable business performance (SBP). Sample size of this study was 500, selected with help of the purposive sampling technique, and 319 responses were saved & used for analysis. Managers of diverse departments were respondents who were linked with small & medium enterprises (SMEs) operating in Punjab, Pakistan. Statistical tools (SPSS-20 & AMOS-21) were utilized for reliability, validity, and hypotheses testing. In light of findings, the study recommends focusing on GTL, GI, and CSR to enhance sustainable business performance & remain competitive in market. Results offer to SMEs managers & policymakers to manage green aspects and CSR practices. It can help managers of SMEs strengthen internal resources to enhance sustainable business performance.
Role of Pesantren in Improving Sociopreneurs of the Community Around Pesantren in Palembang City
Authors: Asrol Safitri , Hesthria Nur , Rizki Oki Sania
Published: April 2023

The function of pesantren besides education and da'wah is community empowerment. One of the implementations of the empowerment function is the role of Pesantren in increasing Sociopreneurship in the community around the pesantren. So, this study suggests the role of pesantren in increasing the Sociopreneurship of the Islamic Boarding School Community in Palembang City. This study uses descriptive qualitative research methods and field research methods. Data collection techniques were carried out using observation, and interviews by distributing 30 questionnaires to pesantren administrators and local communities. The study found that social entrepreneurship in pesantren is carried out by providing students with the skills to run a business and collaborate with SMEs (Micro, Small, and Medium Enterprises) to develop businesses. Pesantren also provides economic assistance to socioeconomically disadvantaged populations. The development of Sociopreunership carried out by pesantren has a positive impact on the community around the pesantren, especially in improvement an living standards.
Comparative Evaluation of the Effects of Pre-sowing Treatments on the Germination and Growth Parameters of Zea mays Linn
Authors: Okereke Chukwu Nkumah , Nwaogaranya Uche Patrick , Ogbu Angela Chinenye , Ikegbunam Clara Nchedochukwu , Iroka Chisom Finian
Published: April 2023

A comparative study on the effects of pre-sowing treatments on the germination and growth of Zea mays was carried out by subjecting the seeds to three treatments at different durations before sowing. The treatments used include; soaking in 30% H2SO4, vernalization and soaking in water (hydotreatment). Soil was filled in 160 polyethene bags of 10 kg each. Five polyethene bags were used for each replicate. With this arrangement, 16 replicates were gotten for the plant according to the treatment and duration placement. Parameters such as germination percentage, plant height, and stem girth as well as leaf area were collected and analyzed using mean, variance, standard deviation, variance of the mean, standard error and confidence limit. The results of the analysis showed that the various treatments and the duration significance on percentage germination and growth parameters of Zea mays seeds. Data presented in Tables 1-14 showed the various treatments and the duration significance on percentage germination of Zea mays seeds. The result showed that the treatment of seeds before cultivation increased the percentage germination in Zea mays when compared with the control replicate. The results revealed the height readings of different treatment sources and treatment durations and how significantly it affected the height of Zea mays. It was also observed that leaf Area and stem girth significantly increased in different treatment methods and durations as seen in treatment of Zea mays. From this research, it was observed that seed treatment resulted in early germination and high growth strength; hence seed treatment with any of the treatments will suffice in giving a better seed performance but for the sake of availability and accessibility of the treatments, hydro-treatment is most recommended.
Ferroelectric Polarization‐Enhanced Performance of Flexible CuInP2S6 Piezoelectric Nanogenerator for Biomechanical Energy Harvesting and Voice Recognition Applications
Authors: Zhang Yunchen , Mao Junqi , Zheng Ren‐Kui , Zhang Jiawei , Wu Yonghui , Wang Xiaobing , Miao Kexin , Yao Hongbo , Yang Liya , Zheng Haiwu
Published: April 2023

2D piezoelectric materials have strong intrinsic piezoelectricity and superior flexibility, which are endowed with huge potential to develop piezoelectric nanogenerators (PENGs). However, there are few attempts to investigate the energy harvesting of 2D ferroelectric materials. Herein, an enhanced output performance is reported by ferroelectric polarization in a PENG with exfoliated 2D ferroelectric CuInP2S6 (CIPS). Specifically, the polarized CIPS‐based PENG produces a short‐circuit current of 760 pA at 0.85% tensile strain, which is 3.8 times higher than that of unpolarized CIPS‐based PENG. Systematical PFM and Raman analysis reveal that the ferroelectric polarization remarkably reinforces the effective piezoelectric constant of CIPS nanoflakes and boosts the in‐plane migration and out‐of‐plane hopping of copper ions, which is the main reason for the enhancement of output performance. Furthermore, the CIPS‐based PENG can not only be utilized to harvest biomechanical energy such as wrist joints movement, but also exhibits a potential for a voice recognition system integrated with deep learning technology. The classification accuracy of a series of letter sounds is as high as 96%. This study commendably broadens the application scope of 2D materials in micro‐nano energy and intelligent sensors, which will have profound implications for exploring wearable nanoelectronic devices.
Educational strategies for general medicine education in accordance with the model core curriculum for medical education in Japan
Authors: Shikino Kiyoshi , Tago Masaki , Hirata Risa , Watari Takashi , Sasaki Yosuke , Takahashi Hiromizu , Shimizu Taro
Published: April 2023

In Japan, the Model Core Curriculum for Medical Education, which is the National Model COre CUrriculum for Undergraduate Medical Education, was first published in 2001 and has since been revised to meet the needs of an aged society and the global standardization of medical education. A new quality and ability “Generalism,” which is a comprehensive attitude toward patients, has been added to this revision of the model core curriculum. In this letter, we propose an educational strategy for generalism.
Radiofrequency labeling strategies in chemical exchange saturation transfer MRI
Authors: Bie Chongxue , van Zijl Peter , Xu Jiadi , Song Xiaolei , Yadav Nirbhay N.
Published: April 2023

Chemical exchange saturation transfer (CEST) MRI has generated great interest for molecular imaging applications because it can image low‐concentration solute molecules in vivo with enhanced sensitivity. CEST effects are detected indirectly through a reduction in the bulk water signal after repeated perturbation of the solute proton magnetization using one or more radiofrequency (RF) irradiation pulses. The parameters used for these RF pulses—frequency offset, duration, shape, strength, phase, and interpulse spacing—determine molecular specificity and detection sensitivity, thus their judicious selection is critical for successful CEST MRI scans. This review article describes the effects of applying RF pulses on spin systems and compares conventional saturation‐based RF labeling with more recent excitation‐based approaches that provide spectral editing capabilities for selectively detecting molecules of interest and obtaining maximal contrast.