bluuebunny/crossref_metadata_2025 huggingface dataset:
Application of VIPs in Canada’s North—Monitoring Results
Authors: Mukhopadhyaya Phalguni , MacLean Doug , Korn Juergen , Mooney Stephen
Published: October 2017

In Canada, known for its cold climate, there is great potential to use vacuum insulation panels (VIPs) for exterior building envelope construction. The introduction of Canada’s 2015 national energy code for buildings has made VIPs a very attractive choice for designers and builders. This new energy code aims to achieve about 25 % less energy use in buildings than the 1997 version of the same. The code changes and Canada’s cold climate have increased interest in better building insulation in general and in VIPs in particular. VIPs have thermal resistance values much greater (5 to 10 times) than those of conventional thermal insulation materials. In the Yukon, VIPs have been used as thermal insulation in two applications where thermal performance monitoring is in progress: (1) in a retrofit of a commercial building and (2) in a new home. This paper summarizes results from the temperature monitoring in the commercial building. These field thermal performance monitoring results, observations, and the lessons learned are presented to help the building enclosure construction community in Canada, and researchers, designers, and end-users around the world, to make the best use of the unique properties and performance of VIPs.
Transcriptomic Analysis of Octanoic Acid Response inDrosophila sechelliaUsing RNA-Sequencing
Authors: Lanno Stephen M , Gregory Sara M , Shimshak Serena J , Alverson Maximilian K , Chiu Kenneth , Feil Arden L , Findley Morgan G , Forman Taylor E , Gordon Julia T , Ho Josephine , Krupp Joanna L , Lam Ivy , Lane Josh , Linde Samuel C , Morse Ashley E , Rusk Serena , Ryan Robie , Saniee Avva , Sheth Ruchi B , Siranosian Jennifer J , Sirichantaropart Lalitpatr , Sternlieb Sonya R , Zaccardi Christina M , Coolon Joseph D
Published: October 2017

The dietary specialist fruit fly Drosophila sechellia has evolved to specialize on the toxic fruit of its host plant Morinda citrifolia. Toxicity of Morinda fruit is primarily due to high levels of octanoic acid (OA). Using RNA interference (RNAi), prior work found that knockdown of Osiris family genes Osiris 6 (Osi6), Osi7, and Osi8 led to increased susceptibility to OA in adult D. melanogaster flies, likely representing genes underlying a Quantitative Trait Locus (QTL) for OA resistance in D. sechellia. While genes in this major effect locus are beginning to be revealed, prior work has shown at least five regions of the genome contribute to OA resistance. Here, we identify new candidate OA resistance genes by performing differential gene expression analysis using RNA-sequencing (RNA-seq) on control and OA-exposed D. sechellia flies. We found 104 significantly differentially expressed genes with annotated orthologs in D. melanogaster, including six Osiris gene family members, consistent with previous functional studies and gene expression analyses. Gene ontology (GO) term enrichment showed significant enrichment for cuticle development in upregulated genes and significant enrichment of immune and defense responses in downregulated genes, suggesting important aspects of the physiology of D. sechellia that may play a role in OA resistance. In addition, we identified five candidate OA resistance genes that potentially underlie QTL peaks outside of the major effect region, representing promising new candidate genes for future functional studies.
False-Positive Newborn Screening for Cystic Fibrosis and Health Care Use
Authors: Hayeems Robin Z. , Miller Fiona A. , Vermeulen Marian , Potter Beth K. , Chakraborty Pranesh , Davies Christine , Carroll June C. , Ratjen Felix , Guttmann Astrid
Published: October 2017

OBJECTIVES:

Evidence is mixed regarding the impact of false-positive (FP) newborn bloodspot screening (NBS) results on health care use. Using cystic fibrosis (CF) as an example, we determined the association of FP NBS results with health care use in infants and their mothers in Ontario, Canada.

METHODS:

We conducted a population-based cohort study of all infants with FP CF results (N = 1564) and screen-negative matched controls (N = 6256) born between April 2008 and November 2012 using linked health administrative data. Outcomes included maternal and infant physician and emergency visits and inpatient hospitalizations from the infant’s third to 15th month of age. Negative binomial regression tested associations of NBS status with outcomes, adjusting for infant and maternal characteristics.

RESULTS:

A greater proportion of infants with FP results had >2 outpatient visits (16.2% vs 13.2%) and >2 hospital admissions (1.5% vs 0.7%) compared with controls; CF-related admissions and emergency department visits were not different from controls. Differences persisted after adjustment, with higher rates of outpatient visits (relative risk 1.39; 95% confidence interval 1.20–1.60) and hospital admissions (relative risk 1.67; 95% confidence interval 1.21–2.31) for FP infants. Stratified models indicated the effect of FP status was greater among those whose primary care provider was a pediatrician. No differences in health care use among mothers were detected.

CONCLUSIONS:

Higher use of outpatient services among FP infants may relate to a lengthy confirmatory testing process or follow-up carrier testing. However, increased rates of hospitalization might signal heightened perceptions of vulnerability among healthy infants.
Reseña "Un pueblo en el camino. Memoria Cultural de San Sebastián de Palmitas"
Authors: Suárez Gómez Juan Diego
Published: October 2017

Reseña de la investigación de memoria cultural de San Sebastián de Palmitas, corregimiento del Municipio de Medellín.
Obispos, clérigos y fieles en pie de guerra. Antioquia, 1870-1880 Ortiz Mesa, Luis Javier. 2010 Medellín: Editorial Universidad de Antioquia ISBN: 978-958-714-360-7
Authors: Londoño Uriza Elidio Alexander
Published: October 2017

Reseña de libro: Obispos, clérigos y fieles en pie de guerra. Antioquia, 1870-1880 de Ortiz Mesa, Luis Javier. 2010. Medellín: Editorial Universidad de Antioquia. ISBN: 978-958-714-360-7
Ghirardi, Mónica y Chacón Jiménez, Francisco, eds. 2010. Dinámicas Familiares en el contexto de los Bicentenarios Latinoamericanos. Córdoba: CIES (CONICET-UNC) / CEA-UNC (Programa Estructuras y Estrategias Familiares de Ayer y de Hoy). ISBN: 9788562016080
Authors: Siegrist Nora
Published: October 2017

La obra de Mónica Ghirardi y Francisco Chacón Jiménez: Dinámicas Familiares en el contexto de los Bicentenarios Latinoamericanos, edita los análisis y trabajos de diversos autores, mediante una división de áreas puntuales tales como: 1. Familias y sociedad: Reflexiones teóricas u debates historiográficos; 2. Matrimonio, celibato y catolicismo ilustrado; 3. Compadrazgos, redes y poder; 4. Familias, justicia y vida material; y 5. Cuestiones de familia en la modernidad.
Peralta Barrera, Napoleón. 2011. Historia de Chiquinquirá. Tomo 1. Tunja: Academia Boyacense de Historia, Colección ruta del bicentenario. ISBN: 978-958-8424-19-4
Authors: Rodríguez Marroquín Angela María
Published: October 2017

“En el ámbito diverso de lo local y regional se arraigan la conciencia histórica, las manifestaciones culturales autóctonas, el amor por las peculiaridades y los sabores, valores y saberes propios, que son los rasgos distintivos de la identidad” (p. 11). Con estas provocadoras palabras Napoleón Peralta Barrera nos introduce al libro Historia de Chiquinquirá, resultado de una investigación, que tiene como objetivo aportar algo nuevo al conocimiento historiográfico del Municipio de Chiquinquirá en el Departamento de Boyacá. Es a partir de  un enfoque local como el autor desde la misma introducción contextualiza, lo que es la historia local y regional, para mostrarnos una historia que va desde el periodo Prehispánico hasta el Republicano, a partir  del transcurrir cotidiano y del ciudadano como actor y participante en la configuración de la historia de la patria chica.
Peña Márquez, Juan Carlos. 2011. Mitú: Ciudad amazónica; territorialidad indígena. Leticia: Universidad Nacional de Colombia. ISBN: 978- 958- 719- 829- 4
Authors: Betancur Hernández Jason
Published: October 2017

En su libro, Juan Carlos Peña Márquez ofrece, de manera creativa, una descripción sobre el proceso histórico, económico y socio-cultural, que dio origen a la ciudad de Mitú, ubicada en la selva de la Amazonía colombiana. Se trata de un texto que muestra el proceso de emergencia urbana en medio de la selva, acaecido con la participación de distintos pueblos y culturas que con sus valores y saberes participaron en el proceso de encuentro intercultural. Con ello, se desprendió la resignificación del territorio y de las identidades culturales para constituir territorialmente una sociedad incluyente donde sus habitantes pudieran relacionarse de la mejor manera.
Reseña del libro Martínez Garnica, Armando. 2012 Historia de la Guardia Colombiana Bucaramanga: Universidad Industrial de Santander - Colección bicentenario ISBN: 978-958-8777-03-0
Authors: Pardo Bueno Luis Miguel
Published: October 2017

El autor realiza un estudio del proceso ideológico y político que condujo a la eliminación del ejército permanente de la Nueva Granada, la creación de la Guardia Colombiana y de los ejércitos estatales durante el periodo federal y el establecimiento del Ejército Nacional en 1886. Para llevar a cabo este estudio, el libro es dividido en cinco capítulos: el primero parte del tránsito ideológico que permitió la creación de la Guardia Colombiana bajo el ideario radical, influenciado por la definición que las constituciones francesas de 1791, 1793 y 1795.
Jane M. Rausch, “…amplíen sus intereses más allá de su propia región y de otros países, además de Colombia, con el fin de poder hacer comparaciones válidas y hacer un caso más claro del contexto de Colombia en el Hemisferio Occidental.”
Authors: Ramírez Bacca Renzo
Published: October 2017

Llegué al aeropuerto de Hartford (Massachusetts) con mi esposa e hija y nos esperaba Jane Rausch, Profesora Emérita de la Universidad de Massachusetts-Amherst. Fue un recibimiento cálido en un anochecer lluvioso y gris del verano de 2013 en Nueva Inglaterra (Estados Unidos). En pocas horas conocimos su estudio y comenzamos a intercambiar trabajos escritos recientes sobre Colombia. Era el inicio de una comisión en la que ella generosamente participaba en calidad de Mentora, gracias al respaldo institucional de la Universidad Nacional de Colombia – Sede Medellín y la Universidad de Massachusetts-Amherst.
Malcom Deas:"...Hay mucho fatalismo en Colombia, basado en lecturas superficiales de su historia.”
Authors: Jimenez Patiño Hernan David
Published: October 2017

Con el interés de contactar unos de los colombianistas más reconocidos en historia política colombiana, contáctate a través de correo electrónico al profesor Malcolm Deas, Profesor Emérito del St Antony’s College  de la Universidad de Oxford, con el interés de realizarle una entrevista virtual, la cual amablemente acepto.
Editorial
Authors: Ramírez Bacca Renzo
Published: October 2017

HiSTOReLo ofrece un variado número de artículos, reseñas y entrevistas en su Vol. 6, No. 12 (2014), perfilados bajo las categorías Iglesia, Empresa, Cultura y Representaciones. Iniciamos con los textos de Nora Siegrist, William Elvis Plata Quezada y Antonio José Echeverry Pérez- Carolina Abadía Quintero quienes abordan el papel de la Iglesia Católica en diferentes temporalidades y espacios. Siegrist, por ejemplo, pone al descubierto el entramado social alrededor de Dispensas y Libros Secretos de Matrimonios entre XVIII y XIX en Argentina; Plata Quezada ofrece su compresión sobre el papel de la Iglesia con relación a la política y la sociedad neogranadina (en la actual Colombia) a partir del análisis sobre los conventos establecidos y desde el caso de la Orden Dominicana durante la primera mitad del siglo XIX; mientras que Echeverry Pérez y Abadía Quintero interpretan el papel de las diócesis en el Valle de Cauca colombiano, en el marco del proceso de modernización y ordenamiento político-administrativo evidenciado en las primeras décadas del siglo XX.
CERATOCYSTIS WILT IN ‘UBÁ’ AND ‘DURA’ MANGO TREES UNDER WATER DEFICIT
Authors: SILVA SAULO DAVID REZENDE DA , SIQUEIRA DALMO LOPES DE , SALOMÃO LUIS CARLOS CHAMHUM , CECON PAULO ROBERTO , ALFENAS ACELINO COUTO
Published: October 2017

ABSTRACT The occurrence of water stress in mango trees grown in orchards located in semi-arid climates in Brazil is frequent. Water stress caused to plants may predispose them to the incidence of fungal diseases. The aim of this study was to evaluate the effect of water deficit on the incidence and severity of Ceratocystis wilt in mango trees considered resistant. Seedlings of ‘Ubá’ and ‘Dura’ were kept in pots and submitted to different water stress levels and inoculated with Ceratocystis fimbriata isolate (CEBS15). Mortality was low in ‘Ubá’ plants and high in ‘Dura’ plants. ‘Ubá’ plants showed lower severity and lesion length. In ‘Ubá’ plants, water deficit influenced the increase in lesion length. ‘Dura’ plants showed greater severity and lesion length, which were not affected by increasing water stress. It was concluded that ‘Ubá’ variety is resistant to fungus Ceratocystis fimbriata, even in severe drought conditions, while ‘Dura’ variety was not resistant to CEBS15 isolate, even under optimum irrigation conditions.
Bispectral index assessment in calves subjected to the continuous infusion of propofol combined with fentanyl administration
Authors: Deschk Mauricio , Trein Thomas Alexander , Wagatsuma Juliana Tessália , Silva Guilherme Lopes da , Araújo Marcelo Augusto de , Games Bruna de Moraes Martins , Alcindo Jefferson Filgueira , Rodrigues Celso Antônio , Santos Paulo Sergio Patto dos
Published: October 2017

ABSTRACT: The aim of this study was to evaluate the bispectral index (BIS) effects in calves through continuous infusion of propofol with or without fentanyl. Eight Holstein male calves (ages from six to twelve months old) with an average weight of 123±18kg were used. All animals participated in both groups, always keeping a minimum interval of one week between the anesthetic procedures; the calves were randomly distributed between groups. Anesthesia was induced with an intravenous (IV) dose of propofol of 5mg kg-1 in control group (GP) or with propofol (4mg kg-1) associated with IV fentanyl 0.001mg kg-1(GF). All the calves were positioned in right lateral recumbency and were allowed to spontaneously breathe room air. Subsequently, the anesthesia was maintained by continuous infusion of propofol at the rate of 0.6mg kg-1 min-1 IV in GP, and associated with the infusion of fentanyl 0.001mg kg-1 hour-1 in GF. Measurements of BIS, signal quality index (SQI) and electromyography (EMG) were evaluated before anesthesia induction (TB), and at 15, 30, 45 and 60 minutes after the beginning of continuous drugs infusion (T15, T30, T45 and T60, respectively). The heart rate (HR), respiratory rate (f), end-tidal carbon dioxide tension (ETCO2) and recovery times were evaluated as well. No significant differences were observed between the groups in the BIS variables and the recovery time was longer in GF. Co-administration of propofol and fentanyl infusions, at the doses reported here, did not change the values of BIS in cattle, but delayed the recovery time.
COM AÇÚCAR, COM AFETO: UM OLHAR ANTROPOLÓGICO SOBRE RITUAIS MATRIMONIAIS A PARTIR DE SUAS MESAS DE DOCES
Authors: Marins Cristina Teixeira
Published: October 2017

Resumo Neste artigo, argumento que as mesas de doces presentes nos rituais matrimoniais ocupam lugar central nos festejos que se seguem à cerimônia de casamento e são atravessadas por dimensões econômicas, morais, materiais, estéticas e afetivas, funcionando como um condensador do ritual. Defendo ainda que, quando observadas atentamente, as mesas de doces são reveladoras da existência de uma hierarquia presente em todo o ritual, bem como de uma temporalidade que é própria dele. Nos últimos anos, venho me dedicando a estudar este ritual de passagem com o intuito de compreender alguns dos significados, códigos e valores nele investidos. O exame do percurso da mesa de doces, desde sua montagem até sua desmontagem, focalizando em especial suas funções sociais e simbólicas, é realizado a partir de material etnográfico construído entre os anos 2011 e 2014.
Marcas de oralidade e memória no Livro das mil e uma noites
Authors: Werneck Mariza Martins Furquim
Published: October 2017

RESUMO O artigo pretende detectar a presença de marcas de oralidade e técnicas de memória presentes em algumas versões do Livro das mil e uma noites. Para isso parte de algumas considerações sobre as técnicas de memória utilizadas na cultura árabe, herdadas da mnemotécnica grega para, em seguida analisar essas marcas sob três perspectivas: como sortilégio (à maneira de Mnemosyne), como forma de imprimir ritmo e cadência aos contos e, finalmente, como arquitetura da memória.
Ensaio sobre o diálogo: as relações intertextuais entre José Saramago, Pieter Bruegel e Van Gogh
Authors: Gomes Murilo de Assis Macedo
Published: October 2017

RESUMO O objetivo deste artigo é demonstrar, com base na teoria de Bakhtin, como se constroem as relações interdiscursivas entre literatura e pintura, mais especificamente entre um diálogo contido na obra Ensaio sobre a cegueira, de José Saramago, e outras obras de arte, como a pintura A parábola dos cegos (1568), de Pieter Bruegel, artista do Renascimento europeu do século XVI, e a tela Trigal com corvos (1890), de Van Gogh, artista expressionista holandês do final do século XIX. Analisar-se-á o modo como o discurso de José Saramago na prosa literária se constituiria a partir da palavra de outrem e como isso caracterizaria uma "dissonância individual", o estilo do autor, em meio à heterodiscursividade inerente ao discurso do romance, como previsto por Bakhtin.
INSCRIÇÕES NO ESPAÇO SOCIAL: OS IMIGRANTES BRASILEIROS NO GRANDE PORTO
Authors: Oliveira Maria João
Published: October 2017

Resumo Este artigo pretende contribuir para o aprofundamento da compreensão dos processos de integração dos imigrantes nas sociedades de acolhimento. Debruçamo-nos sobre os imigrantes brasileiros no Grande Porto com o objetivo de compreender como as migrações - por meio da análise das dimensões social, política e cultural do fenômeno - se relacionam com as inscrições desses imigrantes no espaço social. Enquadrados pela teoria dos sistemas migratórios e com recurso ao inquérito por questionário, os resultados da pesquisa validam a existência de forte relação entre as diferentes dimensões em análise e destacam a influência que a dimensão social assume nos processos de integração. A dimensão cultural ajudou-nos a perceber o efeito bola de neve que algumas categorias das variáveis sociais e políticas assumem na compreensão da forma como o espaço cultural está organizado.
Do controverso “chão da escola” às controvérsias da etnografia: aproximações entre antropologia e educação
Authors: Pereira Alexandre Barbosa
Published: October 2017

Resumo: O artigo discute os dilemas da aproximação interdisciplinar entre antropologia e educação, a partir de duas perspectivas importantes: a etnografia e as práticas culturais juvenis. Aborda-se como a etnografia constitui um ponto controverso de diálogo. Discute também a incontornável e clássica discussão sobre as noções de juventude e de fases da vida, que tem propiciado um debate bastante profícuo, agregando pesquisas que se situam entre a antropologia e a educação. Conclui-se, assim, que a antropologia pode contribuir para o debate público sobre a educação e as diferenças no mundo contemporâneo, mas, para isso, precisa aproximar-se mais do contexto educacional e escolar.
Um estudo da virtualização de processos: o uso de mundos virtuais com foco em ensino-aprendizagem
Authors: NOVELI MÁRCIO , ALBERTIN ALBERTO LUIZ
Published: October 2017

RESUMO Tecnologias de Informação e Comunicação (TICs) têm permitido que processos que dependiam da presença física de indivíduos ou objetos, em um mesmo lugar e tempo, ocorram sem esses limites. Dentre esses, o Processo Ensino-Aprendizagem (PEA) vem ganhando notoriedade, apesar de ainda persistirem dúvidas quando à adequação dessas tecnologias. Portanto, esta pesquisa teve o objetivo de identificar a relação entre requisitos de um processo e capacidades das TICs. Especificamente, foi estudada a adequação dos mundos virtuais à virtualização do PEA, com base na Teoria de Virtualização de Processo (TVP), por meio de evidências advindas de três cursos e analisadas por meio de técnicas de análise de conteúdo e escalonamento multidimensional. Isso resultou em um quadro sistematizado que permite entender o alinhamento entre TIC e requisitos de processo para a sua virtualização, evidenciando quais TICs têm viabilizado o desenvolvimento do PEA.
Temporal coherence of physical, chemical and biological variables in four tropical lakes (Minas Gerais, Brazil)
Authors: Bezerra Mariana Peifer , Barbosa Pedro Maia , Barbosa Francisco Antônio Rodrigues , Bezerra Neto José Fernandes
Published: October 2017

Abstract Aim: The main objective of this study was to evaluate the presence of temporal coherence of limnological variables and pairs of lakes considering four tropical lakes of the Rio Doce State Park, using monthly data from the Long-Term Ecological Research Program (LTER) between the years of 2004 to 2009. Methods Subsurface data (0.5 meters) from the Carioca, Dom Helvécio, Gambazinho, and Jacaré Lakes were used in the analysis. We estimated the temporal coherence from the creation of time series for each of the variables. Through these series, we calculated the Pearson correlation coefficient between all pairs of lakes (N=6) and performed the average. We also analyzed the correlation between the temporal coherence found for the different pairs of lakes and two predictors of spatial patterns: proximity and exposure to climatic factors. The spatial proximity of the lake pairs was calculated in kilometers, and the exposure to climatic factors was estimated using two metrics: surface area and surface area/mean depth ratio. Results The largest temporal coherence levels were recorded for water temperature (0.97), pH (0.78), and dissolved organic carbon (DOC) (0.74). The lowest levels were found for chlorophyll-a (0.25) and phytoplankton richness (-0.02). The average temporal coherence was 0.58. Different from other studies, no significant correlation was found between the synchronicity of the lake pairs and the differences in their exposure to climatic factors. Also, no relation was found with the spatial proximity. Conclusions Our results demonstrate the existence of temporal coherence in tropical lakes to compatible levels with those found in temperate regions. Our work contributes to the knowledge of how synchronicity works at different set of lakes and climatic regions.
Benefits of pre-loading temporary props for braced excavations
Authors: Latapie Benoît , Winarta Terry , Lloyd Steven David
Published: October 2017

Using soil profiles typical of excavations in London, UK and Dubai, UAE calculations have been carried out to compare the performance of temporary steel and proprietary hydraulic propping. Numerical modelling indicates that pre-loading allows the lower-stiffness hydraulic prop to match the performance (in terms of prop load and wall displacement) of a higher-stiffness steel prop, without pre-load. The low prop stiffness also helps to mitigate loading induced by thermal effects. Furthermore, where limiting the horizontal deflection of the wall is critical, the application of a calibrated pre-load can improve the economy of the temporary works by reducing the prop size. Pre-loaded props are sometimes associated with increased bending moment and shear force values in the retaining wall. The finite-element models produced for this paper prove that for the cases considered, the use of pre-loaded low-stiffness hydraulic props achieved the same performance as stiff steel props, with no impact on the wall’s reinforcement. Further work is suggested to explore how manipulating and varying the pre-loading values in multipropped basements might be used to improve further the performance and/or the economy of the retaining wall and how this might affect the load transfer from temporary to permanent supports in the longer term.
Method of mesenchymal stem cells derived ligament tissue v1
Authors: Tsuru Michiyo
Published: October 2017

Our objective was to facilitate ligament tissue reconstruction by characterizing the mechanism of expression of ligament tissue. To accomplish this, we searched for proteins specific to the tissue and introduced them into mesenchymal stem cells. In the two dimensional phosphorescent gel electrophoresis, the spots in common with the normal human ligament tissue were selected after removing the spots of the normal bone tissue from those of the ossified tissue in the spinal ligament. Proline/arginine-rich end leucine-rich repeat protein (PRELP) was identified in ligament-specific locations by liquid chromatography–tandem mass spectrometry. Transfection of PRELP into mouse mesenchymal stem cells yielded ligament-like connective tissue comprised of parallel fibers. Thus, expression of the PRELP protein could reconstruct the ligament tissue. Since zinc-related proteins were found with high incidence as a result of an array analysis of PRELP’s ProtoArray, it was considered that there is a relationship to the zinc metabolism. Tissue induction was mediated by the tumor necrosis factor (TNF)-a via the zinc pathway.PRELP may be a useful gene in syndesmoplasty, provided zinc is present for tissue reconstruction. Chromosome division becomes active with the addition of zinc, and rapid tissue induction takes place in the presence of zinc and TNF-a. Currently, the reconstruction of a ruptured ligament tissue is difficult, but we expect that the PRELP protein expression may facilitate this process. This study describes the discovery of the gene responsible for the differentiation of stem cells into ligament tissue. This important finding may lead to treatments for gonarthrosis, cruciate ligament, and periodontal ligament ruptures, and ossification of the posterior longitudinal ligament.
Phosphoproteomics v1
Authors: Tsuru Michiyo
Published: October 2017

Proteins from the spinal ligament cells of wild-type and null mice were separated using two-dimensional gel electrophoresis and stained with Pro-Q Diamond phosphoprotein gel stain (Thermo Fisher Scientific, Waltham, MA, USA) followed by SYPRO Ruby protein gel stain (Thermo Fisher Scientific). The gel was visualized by using a Molecular Imager FX Pro Plus multi imager system (Bio-Rad, Hercules, CA, USA), and the images were acquired using PDQuest software, version 8.0 (Bio-Rad). The composite images were digitally pseudo-colored and overlaid. The gels were treated with a phosphorylation reagent, and the phosphorylation spots were verified using LC–MS/MS after in-gel digestion using trypsin and peptide extraction, which were performed according to a previously published protocol. Purified peptides (20–30 pmol) were analyzed by using the UltiMate 3000 RSLCnano system (Thermo Fisher Scientific) coupled to an Orbitrap Elite linear ion trap mass spectrometer (Thermo Fisher Scientific) with an in-house manufactured nano-electrospray ionization interface. For micro reversed-phase LC-MS/MS analysis, the samples were injected into a trap column (nano; 75 × 280 μm inner × outer diameter; packed with 15 cm Acclaim Pep Map C18). Buffer A (0.1 % formamide) and Buffer B (80 % acetonitrile and 0.0 8% formic acid) were used to elute the bound peptides with a split flow system (flow rate: 300 nL/min) for 60 min on a linear gradient. In positive ion mode, spectra were acquired with cycles of one full MS scan in the linear trap quadrupole (m/z 350–2000) followed by 20 data-dependent MS/MS scans with a normalized collision energy of 35 %.
A 4-month-old male null mouse walking. Video.1 v1
Authors: Tsuru Michiyo
Published: October 2017

4ヵ月齢のヌードマウスの歩行。
A 4-month-old male wild-type mouse swimming. Video 2. v1
Authors: Tsuru Michiyo
Published: October 2017

A 4-month-old male wild-type mouse swimming. The water temperature was 34 °C.
Evaluation of clinical profile of febrile thrombocytopenia: an institutional based study
Authors: S. Hariprasad , Sukhani Neha
Published: October 2017

Background: Most instances of prolonged fevers are examples of surely understood ailments showing them atypically. Thrombocytopenia is characterized as platelet tally less than 1,50,000/μL. This is because of diminished creation, expanded obliteration, and expanded sequestration in spleen. Hence, we planned the present study to analyse the clinical profile of febrile thrombocytopenia.Methods: The present study included assessment of clinical profile of febrile thrombocytopenia. A total of 200 subjects were included in the present study. At the time of diagnosis, complete detailed history of all the patients was taken along with thorough clinical examination. Etiologic and clinical data of all the patients was recorded and compiled. All the results will be analysed by SPSS software 16.0.Results: Out of total 200 cases included in the present study, fifty-two cases were due to viral fever while fifty-seven cases were due to malaria. Jaundice and cough was present in 52 and 58 cases respectively. In fifty five percent of the cases, platelet count was between 50000 to 10000 per cubic mm.Conclusions: Infectious diseases accounts for most of the cases of febrile thrombocytopenia.
Creatinephosphokinase in organophosphorus poisoning
Authors: Kumar Amith , V. Virupakshappa
Published: October 2017

Background: Organophosphorus Poisoning has been found to be a major cause of death or morbidity in our country as it freely available without need of prescription unlike in developed countries where prescription is required to purchase insecticides, the various organophosphorus compounds available are Malathion, parathion, diazinon, fenthion, dichlorvos, chlorpyrifos, ethion. Erythrocyte cholinesterase (EchE) and pseudocholinesterase (Butyryl cholinesterase-BchE) are markers used for assessing the severity in OP poisoning, but estimation of these are costly, has variable values for different individuals and is not available at all centers. This study was done to estimate levels of serum Creatine Phosphokinase (CPK)serially in acute OP poisoning patients and to correlate with prognosis.Methods: 50 patients of organophosphorus poisoning admitted to Mcgann hospital attached to Shimoga institute of medical sciences Shimoga over a period of 6 months from 1st July 2016 to 31st December 2016 were taken up for the study. A comprehensive history and detailed clinical examination was performed and patients were clinically evaluated for severity. Level of serum cholinesterase and serum CPK were estimated at admission and CPK level was measured on day 3 and day 5. The outcome of these patients was evaluated.Results: Out of 50 patients, 78% (n=39) were males and 22% (n=11) were females. Majority of patients were in the age group 21 – 40 years. Chlorpyrifos was the most common compound used. 72% had mild, 20% had moderate and 8% had severe poisoning. Serial measurements of serum CPK levels showed significant correlation with the severity of acute OP poisoning patients. The CPK levels showed a sensitivity of 74% and a specificity of 81% with a positive predictive value of 92%.Conclusions: Severe organo phosphorus poisoning is correlated with CPK levels. This study recommends CPK level estimation in assessment of severity and prognosticate patients with organophosphorus compound as alternate marker to choline esterase.
The Role of Entitlement, Self-Control, and Risk Behaviors on Dating Violence Perpetration
Authors: Tyler Kimberly A. , Schmitz Rachel M. , Ray Colleen M. , Simons Leslie Gordon
Published: October 2017

Dating violence continues to be pervasive among college students (Stappenbeck & Fromme, 2010). Given the paucity of research investigating the various pathways through which risk factors are linked to dating violence among different college campuses, we use multiple group path analysis to examine the role of child abuse, self-control, entitlement, and risky behaviors on dating violence perpetration among college students from one Southeastern and one Midwestern university. There were 1,482 college students (51% female) enrolled in undergraduate courses at 2 large public universities who completed paper and pencil surveys. Dating violence perpetration was directly associated with gender, child physical abuse, and sexual and drug risk behaviors and indirectly associated with college Greek letter fraternity affiliation, self-control, and entitlement. Moreover, significant differences in the pathways to dating violence were found between the Southeast and Midwest campuses.
Nurse Assessment of Nutritional Status to Identify Patients at Risk for Complications After Pancreatic Resection
Authors: Kintz Tanya , Riley-Doucet Cheryl
Published: October 2017

Purpose/Objectives: To determine if serum prealbumin (PAB) levels can be used by nurses to predict patients who may be at higher risk for postoperative complications after pancreatic surgeries. Design: A quantitative, retrospective study. Setting: One cancer center at an urban medical center in Detroit, Michigan. Sample: A convenience sample of 41 patients with resectable pancreatic neoplasms. Methods: Descriptive study with cross-sectional data using chart review to obtain preoperative PAB levels and perioperative data. Main Research Variables: Pancreatic leak, chyle leak, gastroparesis, sepsis, heart attack, length of hospital stay, and readmissions. Findings: There was a higher incidence of pancreatic leak reported after a distal pancreatectomy; however, this complication was not associated with a low PAB of ≤20 mg/dl. Patients with a diagnosis of adenocarcinoma or who underwent a pancreaticoduodenectomy experienced a longer hospital stay. Conclusions: Results did not reinforce the relationship between preoperative nutritional status and outcomes in pancreatic surgery. Implications for Nursing: Surgical oncology nurses should be aware of the importance of presurgical risk assessment and optimization. Tailored implementation of nutritional prehabilitation to improve patient outcomes after resection of pancreatic neoplasms should be studied more comprehensively.
Mothers’ and Fathers’ Report of Coparenting Relationship Quality, Attitudes Toward Father Involvement, and Paternal Prioritized Roles
Authors: Perry Armon , Rollins Aaron , Grooms Wes , Sabree Ramzi
Published: October 2017

Little is known about mothers’ and fathers’ opinions related to the roles that fathers should prioritize in their parenting. To fill this gap, this study analyzes data collected from parents receiving services from an urban Healthy Start program related to coparenting relationship quality, attitudes toward fathers’ involvement, and the roles that fathers should prioritize in their parenting. The results revealed that mothers had divergent opinions from fathers about the roles that fathers should prioritize in their parenting. Qualitative analyses revealed a link between coresidence and reports of good fathering. Furthermore, the reported discrepancies were related to fathers’ expectations that mothers facilitate their involvement and mothers’ expression of fatigue and resentment from feeling responsible for having to facilitate fathers’ involvement.
Semantic and stylistic features of English texts of journalistic style.
Authors: Hlinka Natalia
Published: October 2017

The article deals with the semantic and stylistic realities of contemporary English-language journalism, briefly lists the main features and characteristics of the functional style of journalistic texts, outlines the techniques that are used in them, and names the particular qualities of their translation in Ukrainian language. Also there are given several examples of the usage of figures of speech and tropes in contemporary English-language journalism such as epithets, metaphors, stylistic comparisons, metonymies and allusions. Also the article provides an example of the difficulties of translation of aforementioned stylistic figures. The article brings the briefsummarized data on the frequency of usage of the stylistic tropes and the figures showing the most productive and the least productive forms. The close relation between language of modern journalism and the cultural environment and impact of this factor during translation is also under consideration of the article. Moreover the article indicates priori conditions of translator language competence, as well as the problems arising on the translation of journalistic materials and ways of overcoming them. As the conclusion the article defines the main translation tasks and connects the methods of resolving the translation obstacles often arising during the translation of modern English-language journalistic texts with the solution of the main translation challenges.
Innovative Technologies in Teaching Students of Technical Specialties: Podcasting.
Authors: Prykhodko Dmytro
Published: October 2017

Due to the fact that Ukraine is the part of the European space, important questions concerning the quality of education have arisen and thus new requirements for the teaching methods and approaches in higher technical educational institutions appear. To improve the quality of education, foreign languages teachers of technical universities are developing new teaching methods. It is very important for educators to use information technologies due to the social and educational informatization. One of the most innovative technologies in contemporary education is podcasting.The suggested paper is devoted to the analysis of podcasting as an innovative technology in the field of foreign language teaching and learning. This paper analyses the application features of the podcasting technology in the learning process. The basic concepts related to the podcasting technology (podcasting, audiocast, vodcast) are defined. The detailed process of audiocast creation is outlined. The main features of the software for audiocast creation are given. The advantages (listening sub-skills formation; listening skills development; the individualized learning intensification; creating conditions for refreshing knowledge and students’ skills reinforcement in the classroom and extracurricular time; multimedia and interactivity; creativity stimulation; usability) and disadvantages (potential abstracting from studying process; audiocast selection problems) of using audiocasts in the educational process are considered.
The role of foreign language in formation of future advertising experts’ professional mobility.
Authors: Natalia Chizhova
Published: October 2017

The paper reveals the meaning of professional mobility, gives some definitions and proves the actuality of its forming in training process of future advertising experts. It demonstrates some examples of “horizontal” mobility among advertising experts. Cognition and communication are main aspects of educational activity which are integrated while learning English. Foreign language doesn’t become the objective of education, but it is the mean of acquisition  and exchanging  information and satisfaction the communication need. Communicative approach is considered to be the main technology in educational process.  Foreign language promotes the development of professional mobility due to intersubject communications, communicative focus and development of cognitive and personal students’ characteristics. Main components of teaching process are disclosed. Pedagogical conditions for formation of professional mobility are defined: intersubject communications, use of information technologies and active forms and innovative methods of teaching. Main forms of interactive technologies are business and role games, multimedia presentations and discussions.  The integration of interactive technologies and intersubject communication is described while teaching foreign language for specific purposes. The perspective of further research is the development of teaching courses based on integration of special subjects with foreign language.
Nerve Growth Factor(s) Mediated Hypothalamic Pituitary Axis Activation Model in Stress Induced Genesis of Psychiatric Disorders
Authors: Kumar Ashutosh , Kumar Pavan , Pareek Vikas , Faiq Muneeb A. , Raza Khursheed , Prasoon Pranav , Mochan Sankat , Sharma Vivek
Published: October 2017

Apart from their established role in embryonic development Nerve Growth Factors (NGFs) have diverse functions in the nervous system. Their role in integration of physiological functioning of the nervous system is now attracting attention. In the present analysis, we propose a new paradigm about a novel role of NGFs. We hypothesize that NGFs play imperative role in maintaining psychological integrity of an individual as a biological system. This function may be mediated through HPA-axis- operated homeostatic mechanisms; stress induced disruption of which may lead to psychiatric disorders. Current literature suggests existence of constitutive homeostatic regulatory mechanisms for NGFs disruption which may lead to important behavioural effects. NGFs have been shown to play crucial parts in endocrine regulation. This is especially true with the prototype ‘NGF’ and Brain Derived Neurotrophic Factor (BDNF). These moieties have been observed to play important role in maintaining neuro-endocrine homeostasis thereby having a profound impact on the psychological health of an individual. Role of NGFs and HPA-axis activation (in separate studies) in developing psychiatric disorders - especially those born of stress - have been established. Literature suggests their unique interplay for producing a common effect which might be implicated in stress induced genesis of psychiatric disorders. This aspect, therefore, needs to be elucidated further as a disease etiogenesis model. This model may yield important insights into the evolution of psychiatric disorders and may open ways for new therapeutic approaches.
Recent Advances on Surface Modification of Halloysite Nanotubes for Multifunctional Applications
Authors: Yang Yongtao , Chen Yun , Leng Fan , Huang Li , Wang Zijian , Tian Weiqun
Published: October 2017

Halloysite nanotubes (HNTs) are natural occurring mineral clay nanotubes that have excellent application potential in different fields. However, HNTs are affected by size effect, surface electron effect and hydrogen bond formation on the surface which lead to weak affinity and prone to reunion at some extent. It is very significant to modify the HNTs’ surface for expand its applications. In this review, the structural characteristics, performance and the related applications of surface modification HNTs are reviewed and summarized. we focus on the surface modified methods of HNTs, the effect of surface modification on materials and its related applications in various regions. In addition, future prospects and the meaning of surface modification have been discussed in HNTs studies. This review provided a reference for the application of HNTs modifications in new fields.
Resource Demand Forecasting Model Based on Dynamic Cloud Workload
Authors: An Chunyan , Zhou Jiantao
Published: October 2017

The primary attraction of IaaS is providing elastic resources on demand. It becomes imperative that IaaS-users have an effective methodology for learning what resources they require, how many resources and for how long they need. However, the heterogeneity of resources, the diversity resource demands of different cloud applications and the variation of application-user behaviors pose IaaS-users big challenge. In this paper, we purpose a unified resource demand forecasting model suiting for different applications, various resources and diverse time-varying workload patterns. With the model, taking input from parameterized applications, resources and workload scenarios, the corresponding resources demands during any time interval can be deduced as output. The experiments configure concrete functions and parameters to help understanding the above model.
Time Series Seasonal Analysis Based on Fuzzy Transforms
Authors: Di Martino Ferdinando , Sessa Salvatore
Published: October 2017

We define a new seasonal forecasting method based on fuzzy transforms. We use the best interpolating polynomial for extracting the trend of the time series and generate the inverse fuzzy transform on each seasonal subset of the universe of discourse for predicting the value of a an assigned output. Like first example, we use the daily weather dataset of the municipality of Naples (Italy) starting from data collected from 2003 till to 2015 making predictions on the following outputs: mean temperature, max temperature and min temperature, all considered daily. Like second example, we use the daily mean temperature measured at the weather station “Chiavari Caperana” in the Liguria Italian Region. We compare the results with our method, the average seasonal variation, ARIMA and the usual fuzzy transforms concluding that the best results are obtained under our approach in both examples.
Ceramic-Based 4D-Components: Additive Manufacturing (AM) of Ceramic-Based Functionally Graded Materials (FGM) by Thermoplastic 3D-Printing (T3DP)
Authors: Scheithauer Uwe , Weingarten Steven , Johne Robert , Schwarzer Eric , Abel Johannes , Richter Hans-Jürgen , Moritz Tassilo , Michaelis Alexander
Published: October 2017

In our study we investigated the additive manufacturing (AM) of ceramic-based Functionally Graded Materials (FGM) by the direct AM technology Thermoplastic 3D-Printing (T3DP). Zirconia components with a varying microstructure were additively manufactured by using thermoplastic suspensions with different contents of pore forming agents (PFA) and were co-sintered defect-free. Different materials were investigated concerning their suitability as PFA for the T3DP process. Different zirconia-based suspensions were prepared and used for AM of single- and multi-material test components. All samples were sintered defect-free and in the end we could realize a brick wall-like component consisting of dense (<1% porosity) and porous (approx. 5% porosity) zirconia areas to combine different properties in one component. The T3DP opens the door to AM of further ceramic-based 4D-components like multi-color or multi-material, especially multi-functional components.
Average Generalized Ambiguity Function Analysis for Passive Bistatic SAR Systems Using PSK Modulating Signal
Authors: Yin Zhiping , Zhang Lei , Xie Jinbao , Yang Jun , Deng Guangsheng , Zeng Zhaoxian
Published: October 2017

The formula of the Generalized Ambiguity Function (GAF) of passive bistatic SAR system using the non-cooperative illuminators which transmit PSK modulating signals is derived to analyze the spatial resolution of the system. The average GAF is introduced to remove the effect of particular sequence of symbols on resolution because the particular sequence of symbols is usually unpredictable before being received. The influence of the waveform parameters of the PSK modulating signals, such as length of the symbol sequence and roll-off factor, on spatial resolution is investigated by numerical simulation. It is confirmed that the influence of the length of the symbol sequence and roll-off factor is very slight but still exists.