bluuebunny/crossref_metadata_2025 huggingface dataset:
The use of smartphone on learning activities: Systematic review
Authors: Firmansyah R O , Hamdani R A , Kuswardhana D
Published: May 2020

This article aims to analyze the use of smartphone technology in education field, with a focus on exploring the effects of smartphone and its software application use in learning activities. This study was conducted using the method of systematic literature review through 3 stages, namely: searching related journals through an online database of several publishers, analyzing the search results journals and dividing them into 3 groups according to the research objectives, and describing the results of the analysis in the form of scientific and logical arguments. From the results of the study it can be concluded that smartphone is significantly useful in student-centered learning, can be used in various disciplines, and at all levels of education, and there are various smartphone applications that can be used for learning needs.
Exhaust temperature and peltier element optimization of thermoelectric generator output
Authors: Setyowidodo I , Sutanto S , Mufarrih A , Sholehah I M
Published: May 2020

The purpose of this study are to obtain (1) the optimum exhaust temperature for the highest voltage output, (2) the optimum number of peltier elements for the highest voltage output, (3) the optimum peltier circuit type for the highest voltage output. The analysis were done to obtain the optimum Seebeck coefficient as a representation of the thermoelectric generator performance. The design of this study is an L20 orthogonal matrix with three replications using a factorial design. The independent variables varied were exhaust temperature and number of peltier elements, while data analysis using ANOVA Two Way. Based on the results of the research data it can be concluded that the furnace wall temperature affects the TEG current output. The optimal wall temperature was 480 °C that produces a TEG current output of 168 mA. This indicates an increase in the temperature of the used metal smelting furnace walls cause the increase in the TEG current output. Meanwhile, the number of peltier elements influenced the TEG current output. The optimum values combination of exhaust temperature and peltier’s number which cause the highest TEG output voltage are 480 °C and 6 (six) peltier element in series circuit, respectively.
Optimal distributed generation placement to reduce power loss using Particle Swarm Optimization method
Authors: Firmansyah M G , Mulyadi Y , Hasbullah H , Saripudin A
Published: May 2020

In electrical power systems, distribution networks have considerable power losses compared with the other parts of electrical power systems. This caused by the distance of power plant to the load center. The high value of power losses causing disadvantage for the electricity provider company. This study aims to reduce power losses in the MLBC feeder distribution network by erecting the distributed generation. The optimal location for erecting distributed generation sought by using the Particle Swarm Optimization (PSO) method. Before distributed generation erected in MLBC feeder distribution network, the power losses’ value is 128.1 kW. Locating the most optimum location for erecting the distributed generation is using the particle swarm optimization method, bus 13 on the MLBC feeder distribution network was the optimum location for distributed generation erection. Hence, the loss value from load flow simulation is 67.5 kW or 60.6 kW for power loss reduction after distributed generation installed on bus 13.
Reliability impact and assesement of distributed generation integration
Authors: Sidik R D N , Mulyadi Y , Trisno B
Published: May 2020

Distribution network is a part of an electric power system that has more intensity of failure than other parts of the power system. This is due to the close distribution network at the load which results in more factors that can be the cause of the failure. The more interference, the worse the reliability index. One effort to improve the feeder reliability index is by connecting Distributed Generation (DG) to feeders. In this study the effect of DG on the reliability index of Malangbong Chocolate (MLBC) feeders will be observed. MLBC is a power secondary substation in the district of Garut in West Java province, Indonesia. The method used in this study is to simulate the reliability of MLBC feeders before and after connecting with DG using the ETAP Power System 16.0 software. The results of the two simulations are then compared to see the effect of DG on the system reliability index. The results show that the SAIFI values before and after using DG connected to bus 4 and bus 5, are 3.8865 and 1.1802 per customer respectively. Whereas the value of SAIDI are 4.3079 and 1.1079 hours per customer in one year respectively. So it can be concluded, the use of DG on feeders can improve the reliability index of the system.
Development of remote laboratory based on HTML5
Authors: Nugraha A T , Haritman E
Published: May 2020

The Laboratory is an important of means for engineering students and the researchers to do various kinds of experiments. Amount of equipment and time to be able to access the laboratory is limited. therefore, in this research developed of remote labs that can be accessed via web anytime and anywhere as long as available internet network. This is in line with the development of Industry 4.0 which introduces cyber physical technology based on internet or wireless network. This technology is not only used for communication but also includes controls and remote control. The results of this research showing the remote lab can be accessed by web via internet and via localhost and compatible with web browser as google chrome, Mozilla, opera etc.
Designing a microcontroller based electric physics experiment board “Mini Serial Lab 01”
Authors: Husni M , Purnama W
Published: May 2020

The importance of STEM (Science Technology Engineering and Mathematics) because of technology development are increase and STEM education’s media are developed. Many company offer STEM education’s media which integrated to data acquisition system and integrated to computer. But not every school or campus can afford that media because of price. To handle this problem in this paper, explain how to make such a STEM education’s media which microcontroller based electric physics experiment board which integrated to data acquisition system. There are 5 experiments on this physics experiment board, the experiments are Series Load, Parallel Load, Series and Parallel Load, RC Natural Response, and Electric Induction. There are three main components which is: hardware, software, and firmware. After three components established and integrated to test the system we do some experiment and then compare the result from measurement and the result from equation. The conclusion was the result from the measurement was close from equation.
Prosthetic hand with 2-dimensional motion based EOG signal control
Authors: Pratomo M R , Irianto B G , Triwiyanto T , Utomo B , Setioningsih E D , Titisari D
Published: May 2020

A prosthetic hand is an artificial device that resembles a human hand which can help the human with a physical disability. Previously, the development of a prosthetic hand is designed in various method, from passive to bionic. Electrooculography (EOG) is a technique for measuring potential differences between the front (positive pole formed by the cornea) and the back (negative pole formed by the retina) of the eyeball which can be used to detect eye movements. The purpose of this study is to design a prosthetic hand with two degrees (2D) of freedom using EOG based control. This system consists of electrodes, EOG amplifier, Bluetooth transmitter-receiver, servo motors, and hand prosthetics. In this study, the system will recognize the eye movements, namely front, right, left, up, and down. The system will recognize the motion based on a threshold value. In the hardware implementation, the system was composed of five electrode sensors which installed around the eye, instrumentation amplifier, high pass filter, low pass filter, noninverting amplifier, summing amplifier, a notch filter circuit, and Arduino UNO microcontroller. In EOG data acquisition, this study involved ten healthy subjects. After the evaluation with five trial for each motion, the error for each eye movement is 0%, 0%, 36%, 4% and 16% for right, left, top, bottom, and front, respectively. This study provided an alternative method to control a prosthetics hand with good performance.
Optimal Power Flow the Sulselrabar 150 KV system before and after the penetration of wind power plants considering power loss and generation costs
Authors: Ilyas A M , Suyuti A , Gunadin I C , Siswanto A
Published: May 2020

Optimal Power Flow (OPF) is to optimize power flow in interconnection systems to decrease production costs and increase system reliability, quality, and stability. This research was conducted on power generation 150 KV systems in South Sulawesi, Southeast Sulawesi, and West Sulawesi, abbreviated as Sulselrabar. The number of buses is 44, 15 generator buses before penetration with the Sidrap Wind Power Plant (PLTB), and 16 bus generators after penetration with PLTB. The method used in this study is Improved Particle Swarm Optimization (IPSO) and Lagrange. The results showed that IPSO showed better results compared to Lagrange and the results of existing systems.
Automatic metal sorting conveyor machine based on Programmable Logic Controller
Authors: Eriyadi M , Mulia S B , Purnomo I R
Published: May 2020

The clothing and food industry had to require for each product which is produced by them is free of dangerous metal. To handle the problem, the industry did anyways to decreasing metal contents that might be involved in the product. One of the methods that the industry able to do is metal sorter automatically system that used to do when the product is on the conveyor. This method is counted so efficiently if we know that the conveyor is used for moving an item from a place to another place by using an induction motor as a mover. This research purposes of presenting an example of a Programmable Logic Controller (PLC) uses as an electronic device that able to control the conveyor metal sorter system automatically. We used a photoelectric sensor to detect an item on the conveyor. Meanwhile, inductive proximity is used to detect metal content behind the item. This research also is written on how this PLC is more efficient if we compared it with using the conventional relay.
Design and realization of (7,4) Hamming code channel encoder trainer using Arduino Mega 2560
Authors: Karostiani N , Pantjawati A B
Published: May 2020

Channel encoder is a part of transmitter block in a digital communication system which is capable of protecting information data from errors by adding parity bits from bits of information. The channel encoder receives bits of information from the source encoder and produces a new code called the codeword. Hamming code is one of the coding mechanisms used to protect information data from errors, with the ability to correct an error. This study explains the design of (7.4) Hamming encoder code channel trainer by using Arduino Mega 2560. The purpose of this research is producing a product that synchronizes a theory with the realization of how the channel encoder blocks work. Important parameters in the encoder channel are information bits, matrix generator, and parity bits. The form of the matrix generator affects the parity bits and the generated codeword. Therefore, the trainer is made and designed that can be used in the form of different matrix generator and qualify of (7.4) Hamming code channel encoder. This trainer is made in two stages: the simulation stage using Proteus 8 Professional and the hardware manufacturing stage. The results showed that the trainers worked in accordance with the theory (7.4) Hamming code channel encoder.
Small Vessel Tracking Based on Multi Gateway LORA for Indramayu Traditional Fishery
Authors: Sumarudin A , Putra W P , Rifai A , Putra A E
Published: May 2020

In this study, we use Lora-based data communication for communication between boats and database management systems for vessel. The maximum distance from the Lora is 10 km, and in order to be able to monitor fishermen along the fisherman’s coast in fishing, it is necessary to have a multi-gateway Lora to increase fishermen’s tracking coverage. The system is built using multi gateway Lora installed on the coast. Devices built with a Lora client are installed on a boat with GPS input, the technique of sending data on the device to the gateway uses a time base with a 1-minute period. To minimize data on the gateway that intersects the range of other gateways, a time flag is made to determine the data at a certain time to determine the trajectory of the boat. The result this research is system-monitoring vessel, which is successfully built and can provide fishing boats along the coast with long-range coverage. Based on experiment, multi gateway can be implemented by creating an identical ID gateway, the Lora client will broadcast to the nearest gateway. The maximum distance obtained is 1.35Km NLOS and to cover 20 Km of beach length is needed 15 gateways.
Design and application of double layer bowtie antenna and single layer bowtie antenna as UHF sensors for partial discharge detection
Authors: Uwiringiyimana J P , Khayam U
Published: May 2020

The reliability of the power system cannot be achieved without good insulation quality of the high voltage apparatus. The Ultra-high frequency (UHF) method has been applied and proven to be accurate in detecting partial discharge (PD) signals emitted from the PD source in the form of electromagnetic waves. This paper discusses the design and application of double layer bowtie antenna and single layer bowtie antenna as UHF sensors for partial discharge detection in air insulation. The PD measurement results obtained by using the designed double layer bowtie antenna were compared with PD measurement results obtained by using the single layer bowtie antenna. The PD characteristics of induced EM waves detected by double layer bowtie antenna and single layer bowtie have been analysed. Based on the simulation results, the double layer bowtie antenna has a minimum return loss values of -31.54 dB and -33.43 dB, with corresponding resonance frequency values of 1.7 GHz and 2.7 GHz, with a total bandwidth of 602 MHz, and corresponding VSWR values of 1.04 and 1.05 while the measurement results by using Vector Network Analyser (VNA) shows that the designed double layer bowtie antenna has a minimum return loss of -20.2 dB, at a resonance frequency of 1.7 GHz, a bandwidth of 576 MHz and corresponding VSWR of 1.2. The single layer bowtie antenna has a bandwidth of 240 MHz, a minimum return loss of -24 dB, at a resonance frequency of 1.28 GHz, and a VSWR of 1.13 based on the simulation results while the single layer bowtie antenna has a bandwidth of 298 MHz, a minimum return loss of -23.32 dB, at a resonance frequency of 1.3 GHz, and a VSWR of 1.14 based on the measurement results by using VNA. The bowtie antennas were designed using the 3D-HFSS software with FR4-epoxy substrate type and later on were printed on the Printed Circuit Board (PCB). The PD measurement data were performed by using the applied voltage level of 7 kV. According to the antennas simulation results, antennas measurement results by VNA and PD measurement results, the double layer bowtie antenna has proven to be more sensitive than the single layer bowtie antenna.
Low interaction honeypot as the defense mechanism against Slowloris attack on the web server
Authors: Fitri N R , Budi A H S , Kustiawan I , Suwono S E
Published: May 2020

Threats and attacks on internet services are in line with developments in internet technology. One of the main risks is Distributed Denial of Service (DDoS). In this paper, we focus on the Slowloris attack which is an open-source DDoS attacker that generally attacks the Apache webserver. Apache is one of the most popular web servers in the world and is still used by many companies. This research presents another way to reduce attacks to the firewalls and load a counterweight by using a low interaction honeypot, HoneyPy. In normal conditions, attack schemes and defense mechanisms are evaluated by conducting experiments. Slowloris attacks cause high traffic because it prevents the socket from closing, so the webserver cannot handle other connections from legitimate users. When defense mechanisms are applied to the network, Slowloris attacks that enter the webserver are minimized because most packets are discarded and directed to the honeypot without the attacker’s knowledge. It seems like the attacker has managed to attack the web server even when the attack becomes slower.
Characteristics of hardness at local propellers with variations of timing by using sandblasting method
Authors: Endramawan T , Sifa A , Dionisius F
Published: May 2020

Sandblasting is one method of surface treatment that aims to improve the characteristics of material properties, such the hardness materials. This process was done by spraying abrasive material onto the surface of the object with the pressure. The purpose of this study was to increase the hardness of local propellers as a result of the sandblasting process. In this study, the material used aluminum alloys in the form of propellers of local fishing boats. While abrasive material used aluminum oxide with size 100 mesh. Then the pressure used 3, 4, and 5 bars with 25, 50, and 75 seconds in shooting times by angle 90. Measurement of hardness value used Universal Hardness Tester by macro-Vickers with load parameters 5 Kgf and indentation time of 10 seconds. The results showed that the longer the shooting time, the hardness of the propeller be increased 32.4% from the material that has not been carried out by the sandblasting process. The factor of time variation and shooting pressure has a significant effect on the results of the hardness in the specimen.
Electrospinning and characterization nanofibers and nano particle of Polyvinylpyrrolidone
Authors: Virginia C , Khasanah A , Jauhari J , Sriyanti I
Published: May 2020

Electrospinning method used to fabricate fibers both micrometers and nanometers scale. Nanofibers of Polyvinylpyrrolidone (PVP) have been developed using an electrospinning method. It is PVP acting as matrix and ethanol analyst as a solvent. We used the same concentrate of PVP I namely 10% (w/v) for three difference molecule-weight materials namely PVP 1.300.000 kg/mol (PVP-1), PVP 360.000 kg/mol (PVP-2) and PVP 40.000 kg/mol (PVP-3). The spinning process of the three molecule-weight PVP could be produced with various parameters, 0.3 flowrate, 10 kV voltage, and 12 cm needle length. Observation using a microscope shows the morphology of each solution (PVP-1), (PVP-2), (PVP-3) will generate large fibers, medium fiber, and nanofibers. The diameter of each fiber is 2620, 1760 and 1380. From the diameter analysis, we conclude that a smaller molecule-weight of PVP will obtain smaller fibers. The FTIR results give an overview of the interactions between PVP molecules that are shown against the PVP peaks. Nanofibers and nanoparticles can be applied in medicine, high-performance air filters, military and medical protective textiles, sensors, advanced composites, photo vault cells, and separation membranes. This study will show the difference form of PVP with the same concentrate for three difference molecule-weight.
The effect of a single quenching double tempering process on the mechanical properties of NiCrMo alloyed steel casting
Authors: Bandanadjaja B , Purwadi W , Lilansa N , Idamayanti D , Putra T R S
Published: May 2020

This research aimed to improve the mechanical properties of NiCrMo alloyed steel casting, especially in terms of toughness. Toughness is a combination of tensile strength, yield strength, and elongation. The method used was a multi-heat treatment process involves normalizing, tempering, double tempering, and an additional intermediate process of quenching. The results obtained through the normalizing process followed by single quenching on oil media and double tempering (single quenching double tempering) produced the best-combined result of tensile strength, yield strength, and elongation. The modulus of toughness increased by up to 745 % compared to the as-cast condition from 20 N.mm/mm3 to 149 N.mm/mm3. The best mechanical properties were obtained from tempered martensite microstructure. It is free from rest martensite and secondary carbide.
Lifetime simulation of traditional boat propellers using Ansys
Authors: Endramawan T , Sifa A , Dionisius F , Syah M I
Published: May 2020

In this study an age-predictive simulation of propellers used by traditional fishermen in the Indramayu region was carried out. These boats were driven by gasoline or diesel motors to drive boat propellers. This boat propeller is made of aluminum alloy with gravity casting technique. The problem is that there are many fishermen who fail on their propellers which generally occur faults on the propeller fins, the purpose of this study is to predict fatigue and age of propellers used in traditional boats, with the observation and calculation method of Finite Element Analysis (FEA) using Ansys software. The results of lifetime propeller analysis with variability in boat hull loading and boat load, with different variations between 3488N and 4788 N, obtained a lifetime for the loading did not experience a significant difference with a lifetime of 277,7 hours.
Traffic sign detection and recognition by improving Region of Interest (ROI) division to support driver assistance system
Authors: Suheryadi A , Sumarudin A , Puspaningrum A , Prastyo E
Published: May 2020

Traffic signs detection and recognition is a technology that allows automatic identification of traffic signs. In the implementation, it mostly uses a camera to capture video or real-time conditions. The Traffic detection and recognition system can give benefits to improve safety for drivers or passengers. Therefore, traffic signs detection and recognition system are one of the important parts in Driver Assistance Systems (DAS), besides that it is also used in video surveillance to improve traffic safety in the field of Intelligent Transportation System (ITS). In this paper, we propose a method for detecting and recognizing traffic signs by combining color and shape detection and divide the interest object to several regions for object recognition. The first step is image transformation, which aims to determine interest objects in the camera view. Such a process was using hue, saturation, value (HSV) color space, grey level, and black and white (BW) level. The next step is the filter and the segmentation process. The result of the filter and segmentation process then detects area objects by using region determination. The last step is the region of interest (ROI), which is used to recognizing sign traffic by the sum of absolute differences (SAD), and we try to improve area selection of ROI around nine parts. The results of the experiment proved that the proposed method was relatively good with the success rate for detecting objects about 97,38 %, and the true positive of recognition result about 81,67 %.
Performance analysis of Pico Hydro-Solar Photovoltaic Hybrid System
Authors: Ratnata I W , Sumarto S , Saputra W S
Published: May 2020

This paper presents experimental results from the operation of the prototype of Pico Hydro-Solar Photovoltaic Hybrid System. This device includes a pico hydro power with a capacity of 600 VA, a 3x200 WP solar panel, 4x60Ah energy storage, solar charge controller, a 1500 W inverter, and a 15-200 watt variable load. In this experiment, measurements of the current flow and terminal voltage were carried out at the output of photovoltaic, picohydro, battery, and inverter at various different load values, ranging from 15 watts to 200 watts. Measurements are made during the day when the intensity of solar radiation is quite high. The measurement results show that the output voltage on each component is relatively stable at various load values, and the load energy requirements are supplied more by solar photovoltaic components in sunny weather and more by pico-hydro in cloudy weather.
Oyster mushroom cultivation solution based IoT for Nova Farmers
Authors: Fauzi R M , Waranti F S , Rais I K , Somantri Y
Published: May 2020

Nova Farmers is a group of oyster mushroom farmers in Pasirhalang Village, Cikarangmulya, West Bandung, which has a vertical mushroom baglog. Farmers who are dominated by women need to climb Baglog to water Baglog at every level. The purpose of this study is to design a tool that can maximize the growth of oyster mushrooms, temperature, and humidity of the kumbung to be maintained at temperatures of 28 ° C and 80% through watering. To improve watering techniques by farmers, oyster mushroom sprinklers are automatically made based on the Internet of Things that takes into account temperature and humidity factors that can be monitored and controlled through the ABUJAT android application using Android Studio software. The sprinkler section can move vertically up and down to be able to sprinkle all baglogs at each level. This system is made using a DC PG45 motor to drive the sprinkler section which is controlled by DOIT ESP32 DevKit V1 as a microcontroller and combined with a DHT22 sensor as a temperature and humidity sensor, DS1307 RTC module, water sensor, buzzer module for watering the alarm notification, 12VDC pump for pumping water, 16x2 LCD to display sensor values, limit switches, and BTS7960 motor drivers. Based on the results of the experiment, our application can function properly and can be used by Nova Farmers.
Synthesis of ZnO/C dots as antibacterial dental bracket
Authors: Taufiq H R , Mirza M , Paramita S A , Sutanto H
Published: May 2020

Demineralization brackets has caused serious problems in orthodontic techniques effect by increasing streptococcus mutans bacteria in the mouth. To overcome this problem, antibacterial brackets based on ZnO and carbon dots materials were made using spray coating-microwave irradiation methods which have environmentally friendly, non-toxic and low-cost. C-dots with variations power of microwave are 450 W and 540 W were successfully made with microwave time of 15, 30 and 45 minutes. Optical properties showed the highest absorbance owned by ZnO/C-dots at 15 minutes and power of 450 W. Data obtained in the form of absorbance graphs were then processed using the Tauch Plot method to determine the value of the energy band gap. The shift of light absorption of ZnO/C-dots towards the higher wavelength causes a decrease in the energy band gap of 3.16 eV from before ZnO value is 3.26 eV. Therefore, ZnO/C-dots is effectively used under visible light radiation. After modification with C-dots, the surface of the bracket shows a more rugged morphology, covered by a dense and uniform ZnO/C-dots layer which is useful for protecting brackets.
Photocatalytic degradation of heavy metal in dairy milk by N-doped ZnO thin film using spray coating technique
Authors: Pratiwi N I , Ilsatoham M I , Asror M Z , Sutanto H
Published: May 2020

Zinc Oxide (ZnO) is a photocatalytic material. N-doped ZnO thin film can reduce heavy metals in milk. In the process, N-doped ZnO thin film photocatalyst is deposited on the glass by spray coating technique. N-doped ZnO thin film was characterized using UV-Vis (Ultraviolet/Visible Spectroscopy), X-Ray Diffraction (XRD) and FTIR (Fourier Transform Infrared). This study aims to investigate the reduction of heavy metals in milk due to N-doped ZnO thin film. In this study, dairy milk was obtained from farms in Central Java. Characterization results show that the band gap of N-doped ZnO thin film is 3.2 eV that N- doped ZnO thin film can function under visible light. Photocatalytic activity of prepared N-doped ZnO thin film was evaluated by the degradation of heavy metals in dairy milk. Duration of N-doped ZnO thin film degradation was found to vary from 0, 60, and 120 to 180 minutes. Heavy metal content in dairy milk is 0.5775 ppm. Addition of N-doped ZnO thin film to dairy milk reduced heavy metal content to 0.0053 ppm. In can then be inferred that heavy metal degradation using N-doped ZnO thin film is by as much as 89-99 %.
The sensitivity of sensor based on Microring Resonator (MRR) and Surface Plasmon Resonance (SPR) for diabetes monitoring application
Authors: Nugroho H S , Hasanah L , Wulandari C , Pawinanto R E , Haron M H , Menon P S , Zain A R M , Berhanuddin D D , Mulyanti B
Published: May 2020

Diabetes mellitus is a disease of metabolic disorders where human blood contains a high amount of sugar level for a prolonged period. This study aims to simulate how effective sensor based on MRR and SPR for the purpose of diabetes monitoring. The results show that sensor based on MRR and SPR provides the ability to detect low level of glucose concentration as low as 7 mmol/L (0.13%) and the ability to detect resonance shift for very small glucose concentration change. Therefore, the sensor based on MRR and SPR can be used for diabetes monitoring. The sensitivity of the sensor based on MRR and SPR is 85.84 nm/RIU and 116.69 °/RIU respectively. These findings are important for the development of diabetes monitoring based on MRR or SPR.
Analysis characteristic of cholesteryl acrylate conductivity with the addition of the PE-b-PEG doped ITO-nanoparticle in the development of liquid crystal technology
Authors: Ismail M , Afrizal A , Syafei D I , Puspita M A
Published: May 2020

The study of liquid crystal material is very interesting and has the opportunity as a smart material such as cholesteryl acrylate. Liquid crystal cholesteryl acrylate can be made shynthesized by Acryloiloxy Butyloxy Benzoate (ABB) precursor and cholesterol. Cholesteryl acrylate was polymerized by the ultraviolet curing (UV-Curing) method to keep the crystal structure stable. During the polymerization process some ingredients are added which can increase and regulate the formation of liquid crystal structure phases. Cholesteryl acrylate can be doped by adding conductive oxide in the form of nano particle scale Indium Tin Oxide (18 nm). The optimum conductivity results were 5.70 × 10−7 S/m with the addition of ITO 10% w/w. The structure of the crystal phase formed can be directed by the addition of Polyethylene-block-Polyethylene Glycol during the UV-Curing process. The hydrophobic part of PE block will interact with hydrophobic liquid crystal molecules, while the hydrophilic part of the PEG block has a high affinity for the hydrophilic ITO electrode substrate. The added PE-b-PEG varies from 0.001 to 0.005 percent by weight of polymer cholesteryl acrylate composite. Conductance data is measured using LCR meters from a frequency of 50 Hertz to 5000 kHertz. The average conductance data for ITO is 0.09597838 S, cholesteryl acrylate is 5.20635 × 10−6 S, the polymer cholesteryl acrylate composite with doped ITO is 4.58284 × 10−6 S. When added PE-b-PEG 0,003 percent composite weight is obtained the highest average conductance data is 1.24234 × 10−5 S with an average conductivity value of 6.09 × 10−5 S/m. The varies composition of PE-b-PEG content is very influential to regulate the arrangement of crystals formed in electrical conductivity.
Design of a compact UWB Wilkinson Power Divider using ring structured and tapered line matching transformer
Authors: Yuniar R N , Hariyadi T , Saripudin A , Mulyanti B
Published: May 2020

There is an increasing interest in the design of ultra-wideband (UWB) microwave components for UWB applications. One of the important components in the ultra-wideband application is power divider. In this paper, an ultra-wideband Wilkinson power divider (WPD) using ring structure and tapered line matching transformer is proposed. The aims of this research are to design an UWB WPD for feeding antenna UWB in use of detecting breast cancer. The method used in this research is simulation using finite integration based on CST STUDIO SUITE 2015 3D EM simulator software. This study shows the improvement of output responses due to the introduction of a tapered line and added isolation resistors. The bandwidth and input reflection coefficient are also improved by the ring structure. The proposed UWB WPD can be used for 1:2-way equal power division application in ultra-wideband range, such as UWB antenna which is operating in frequency 3-13 GHz. The simulation result shows that the return loss is better than -10 dB and the insertion loss is about 3.2 dB until 4.15 dB for the operating frequencies and impedance value of 50 ohms.
Design of array microstrip antenna with circular polarization for Broadband Tracking System Application
Authors: Alam S , Surjati I , Sari L , Ningsih Y K , Wibowo T
Published: May 2020

This paper proposes the design and simulation of microstrip array antennas with 4x1 elements that have circular polarization for Broadband Antenna Tracking System (BATS) applications. The proposed antenna is designed to work at a frequency of 11 GHz by using FR-4 type substrate with a dielectric constant 4.3, thickness (h) 1.6 mm and loss tangent (tan α) 0.0265. Circular polarization with axial ratio ≤ 3 dB was obtained using the truncated corner technique while the 4x1 element array technique was used to increase the bandwidth of the proposed antenna. From the simulation results obtained return loss of -29.71 dB and VSWR 1.068 at the working frequency of 11 GHz. The bandwidth of the proposed antenna is 1663 MHz in the frequency range 10582 GHz - 12215 MHz. The axial ratio of the proposed antenna is ≤ 3 dB, which is 2.462 dB at the working frequency of 11 GHz. Based on the results obtained from the design and simulation process, the proposed antenna has worked in accordance with the specified working frequency and is suitable for the Broadband Tracking System application.
Design and realization of 4 way Chebyshev Wilkinson power divider at 3 GHz frequency for 3 dimensional radar application
Authors: Khoirini D R , Hariyadi T , Pantjawati A B
Published: May 2020

In the radar system, detection of objects with high accuracy is needed. Therefore, a low sidelobe antenna is needed to avoid interference from other detected targets. One method to suppress sidelobe antenna is by using unequal power divider with Chebyshev polynomial excitation coefficients. In this paper, we will discuss about the design and fabrication of Chebyshev Wilkinson power divider for 3 dimensional radar application. This research was conducted through 4 stages, namely design, simulation, fabrication and measurement. This power divider is realized in the form of a microstrip using Rogers R0-4003C (lossy) substrate with a thickness of 1,524 mm and a dielectric constant of 3.55. The simulation and measurement results are met the desired specifications, the operating frequency is at 3 GHz with a bandwidth of 200 MHz, the return loss is less than -10 dB, the insertion loss value is in accordance with Chebyshev, the isolation value of the port is less than -10 dB, and the unbalance phase is smaller than 2.5°.
Analysis of the relevance between Vocational High School competencies and the needs of the industrial sector on Computer and Network Engineering Competencies
Authors: Kamilah S , Budi A H S , Purnama W
Published: May 2020

The curriculum applied in vocational schools aims to synchronize graduate competencies with the demands of the industrial sector on workforce competencies. This study aims to analyze the relevance of the 2013 Vocational High School curriculum on Computer and Network Engineering Competencies and the needs of the workforce in the Telecommunications Industry Sector. This research was conducted using quantitative descriptive methods. The study population was the Vocational High School and the Telecommunications Industry in West Java Province and DKI Jakarta. The sample is determined by purposive sampling technique for the Telecommunications Industry and saturated sampling for Vocational High Schools. Participants in this study were 6 respondents from the Vocational High School and 21 respondents from the Telecommunications Industry. The research instrument used was a questionnaire. The analysis technique used is recall and precision. The results showed a high relevance between Basic Competence in the field of computer and network engineering and the need for workforce in the telecommunications industry sector by 83.84%.
Early Outpatient Treatment of Symptomatic, High-Risk COVID-19 Patients That Should Be Ramped Up Immediately as Key to the Pandemic Crisis
Authors: Risch Harvey A
Published: May 2020

More than 1.6 million Americans have been infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and more than 10 times that number carry antibodies to it. High-risk patients with progressing symptomatic disease currently have only hospitalization treatment, with its high mortality, available to them. An outpatient treatment that prevents hospitalization is desperately needed. Two candidate medications have been widely discussed: remdesivir and hydroxychloroquine (HCQ) + azithromycin (AZ). Remdesivir has shown mild effectiveness in hospitalized inpatients, but no trials in outpatients have been registered. HCQ + AZ has been widely misrepresented in both clinical reports and public media, and results of outpatient trials are not expected until September. Early outpatient illness is very different from later florid disease requiring hospitalization, and the treatments differ. Evidence about use of HCQ alone, or of HCQ + AZ in inpatients, is irrelevant with regard to the efficacy of HCQ + AZ in early high-risk outpatient disease. Five studies, including 2 controlled clinical trials, have demonstrated significant major outpatient treatment efficacy. HCQ + AZ has been used as the standard of care in more than 300,000 older adults with multiple comorbid conditions; the estimated proportion of such patients diagnosed with cardiac arrhythmia attributable to the medications is 47 per 100,000 users, among whom estimated mortality is less than 20% (9/100,000 users), as compared with the 10,000 Americans now dying each week. These medications need to be made widely available and promoted immediately for physicians to prescribe.
Joint reconstruction of cis-regulatory interaction networks across multiple tissues using single-cell chromatin accessibility data
Authors: Dong Kangning , Zhang Shihua
Published: May 2020

The rapid accumulation of single-cell chromatin accessibility data offers a unique opportunity to investigate common and specific regulatory mechanisms across different cell types. However, existing methods for cis-regulatory network reconstruction using single-cell chromatin accessibility data were only designed for cells belonging to one cell type, and resulting networks may be incomparable directly due to diverse cell numbers of different cell types. Here, we adopt a computational method to jointly reconstruct cis-regulatory interaction maps (JRIM) of multiple cell populations based on patterns of co-accessibility in single-cell data. We applied JRIM to explore common and specific regulatory interactions across multiple tissues from single-cell ATAC-seq dataset containing ~80 000 cells across 13 mouse tissues. Reconstructed common interactions among 13 tissues indeed relate to basic biological functions, and individual cis-regulatory networks show strong tissue specificity and functional relevance. More importantly, tissue-specific regulatory interactions are mediated by coordination of histone modifications and tissue-related TFs, and many of them may reveal novel regulatory mechanisms.
Accurate prediction of genome-wide RNA secondary structure profile based on extreme gradient boosting
Authors: Ke Yaobin , Rao Jiahua , Zhao Huiying , Lu Yutong , Xiao Nong , Yang Yuedong
Published: May 2020

Motivation

RNA secondary structure plays a vital role in fundamental cellular processes, and identification of RNA secondary structure is a key step to understand RNA functions. Recently, a few experimental methods were developed to profile genome-wide RNA secondary structure, i.e. the pairing probability of each nucleotide, through high-throughput sequencing techniques. However, these high-throughput methods have low precision and cannot cover all nucleotides due to limited sequencing coverage.

Results

Here, we have developed a new method for the prediction of genome-wide RNA secondary structure profile from RNA sequence based on the extreme gradient boosting technique. The method achieves predictions with areas under the receiver operating characteristic curve (AUC) >0.9 on three different datasets, and AUC of 0.888 by another independent test on the recently released Zika virus data. These AUCs are consistently >5% greater than those by the CROSS method recently developed based on a shallow neural network. Further analysis on the 1000 Genome Project data showed that our predicted unpaired probabilities are highly correlated (>0.8) with the minor allele frequencies at synonymous, non-synonymous mutations, and mutations in untranslated regions, which were higher than those generated by RNAplfold. Moreover, the prediction over all human mRNA indicated a consistent result with previous observation that there is a periodic distribution of unpaired probability on codons. The accurate predictions by our method indicate that such model trained on genome-wide experimental data might be an alternative for analytical methods.

Availability and implementation

The GRASP is available for academic use at https://github.com/sysu-yanglab/GRASP.

Supplementary information

Supplementary data are available online.
AOP4EUpest: mapping of pesticides in adverse outcome pathways using a text mining tool
Authors: Jornod Florence , Rugard Marylène , Tamisier Luc , Coumoul Xavier , Andersen Helle R , Barouki Robert , Audouze Karine
Published: May 2020

Motivation

Exposure to pesticides may lead to adverse health effects in human populations, in particular vulnerable groups. The main long-term health concerns are neurodevelopmental disorders, carcinogenicity as well as endocrine disruption possibly leading to reproductive and metabolic disorders. Adverse outcome pathways (AOP) consist in linear representations of mechanistic perturbations at different levels of the biological organization. Although AOPs are chemical-agnostic, they can provide a better understanding of the Mode of Action of pesticides and can support a rational identification of effect markers.

Results

With the increasing amount of scientific literature and the development of biological databases, investigation of putative links between pesticides, from various chemical groups and AOPs using the biological events present in the AOP-Wiki database is now feasible. To identify co-occurrence between a specific pesticide and a biological event in scientific abstracts from the PubMed database, we used an updated version of the artificial intelligence-based AOP-helpFinder tool. This allowed us to decipher multiple links between the studied substances and molecular initiating events, key events and adverse outcomes. These results were collected, structured and presented in a web application named AOP4EUpest that can support regulatory assessment of the prioritized pesticides and trigger new epidemiological and experimental studies.

Availability and implementation

http://www.biomedicale.parisdescartes.fr/aop4EUpest/home.php.

Supplementary information

Supplementary data are available at Bioinformatics online.
Knockout of family with sequence similarity 170 member A (Fam170a) causes male subfertility, while Fam170b is dispensable in mice†
Authors: Devlin Darius J , Nozawa Kaori , Ikawa Masahito , Matzuk Martin M
Published: May 2020

Families with sequence similarity 170 members A and B (FAM170A and FAM170B) are testis-specific, paralogous proteins that share 31% amino acid identity and are conserved throughout mammals. While previous in vitro experiments suggested that FAM170B, an acrosome-localized protein, plays a role in the mouse sperm acrosome reaction and fertilization, the role of FAM170A in the testis has not been explored. In this study, we used CRISPR/Cas9 to generate null alleles for each gene, and homozygous null (−/−) male mice were mated to wild-type females for 6 months to assess fertility. Fam170b−/− males were found to produce normal litter sizes and had normal sperm counts, motility, and sperm morphology. In contrast, mating experiments revealed significantly reduced litter sizes and a reduced pregnancy rate from Fam170a−/− males compared with controls. Fam170a−/−;Fam170b−/− double knockout males also produced markedly reduced litter sizes, although not significantly different from Fam170a−/− alone, suggesting that Fam170b does not compensate for the absence of Fam170a. Fam170a−/− males exhibited abnormal spermiation, abnormal head morphology, and reduced progressive sperm motility. Thus, FAM170A has an important role in male fertility, as the loss of the protein leads to subfertility, while FAM170B is expendable. The molecular functions of FAM170A in spermatogenesis are as yet unknown; however, the protein localizes to the nucleus of elongating spermatids and may mediate its effects on spermatid head shaping and spermiation by regulating the expression of other genes. This work provides the first described role of FAM170A in reproduction and has implications for improving human male infertility diagnoses.
3,3-Diindolylmethane (DIM): a nutritional intervention and its impact on breast density in healthy BRCA carriers. A prospective clinical trial
Authors: Yerushalmi Rinat , Bargil Sharon , Ber Yaara , Ozlavo Rachel , Sivan Tuval , Rapson Yael , Pomerantz Adi , Tsoref Daliah , Sharon Eran , Caspi Opher , Grubsrein Ahuvah , Margel David
Published: May 2020

Women who carry the BRCA mutation are at high lifetime risk of breast cancer, but there is no consensus regarding an effective and safe chemoprevention strategy. A large body of evidence suggests that 3,3-diindolylmethane (DIM), a dimer of indole-3-carbinol found in cruciferous vegetables, can potentially prevent carcinogenesis and tumor development. The primary aim of this prospective single-arm study was to investigate the effect of DIM supplementation on breast density, a recognized predictive factor of breast cancer risk. Participants were 23 healthy female BRCA carriers (median age 47 years; 78% postmenopausal) who were treated with oral DIM 100 mg × 1/day for 1 year. The amount of fibroglandular tissue (FGT) and background parenchymal enhancement (BPE) on magnetic resonance imaging (MRI) performed before and after the intervention was scored by two independent expert radiologists using the Breast Imaging and Reporting Data System. The results showed a decrease in the average score for FGT amount from 2.8 ± 0.8 at the onset to 2.65 ± 0.84 after 1 year (P = 0.031), with no significant change in BPE (P = 0.429). A group of DIM-untreated age- and menopausal-status-matched women from the BRCA clinic did not show a significant change in FGT amount (P = 0.33) or BPE (P = 0.814) in a parallel year. Mean estradiol level decreased from 159 to 102 pmol/l (P = 0.01), and mean testosterone level decreased from 0.42 to 0.31 pmol/l (P = 0.007). Side effects were grade 1. In conclusion, 1 year’s supplementation with DIM 100 mg × 1/day in BRCA carriers was associated with a significant decline in FGT amount on MRI. Larger randomized studies are warranted to corroborate these findings.