bluuebunny/crossref_metadata_2025 huggingface dataset:
RESULTS OF COMBINED TREATMENT PATIENTS WITH SOFT TISSUE SARCOMAS USING STEREOTACTIC ABLATIVE BODY RADIOTHERAPY
Authors: Gafton Georgiy , Ebert Mariya , Novikov S. , Fedosova E. , Zinovev G. , Kanaev S. , Gafton I. , Sinyachkin M.
Published: November 2020

Preoperative radiotherapy in patients with soft tissue sarcomas characterized by important advantages: high precision of dose delivery, reduction of tumour volume and implantation potential, induction of immunologic response. Postoperative radiotherapy associated with decreased complication rate, delivery of treatment to microscopic disease according to pathologic report. Combination of pre- and postoperative irradiation gives the opportunity to use best of both methods. The aim: analyses of feasibility and safety of radiotherapy protocol that combined pre- and postoperative radiotherapy in patients with soft tissues sarcomas of extremities. Materials and methods: from 06.2018 to 01.2020 ten patients with soft tissue sarcomas of extremities were included in the protocol. Preoperative stereotactic ablative body radiotherapy (SABR) was performed as 5 fraction of 7 Gy on the main tumor volume with dose reduction to 5Gy in 5 fraction on the margins of the field. Postoperative radiotherapy started 5-8 weeks after surgery and was performed as standard compartmental irradiation in 25 fractions of 2Gy. Complications were determined according to CTCAE and wound complication scales. Results: from 06.2018 to 01.2020 10 patients with soft tissue sarcomas of extremities were included in the study. Pre-opeartive SABR and subsequent radical resection with tumor free surgical margins were performed in all 10 cases. Primary wound closure was mentioned in all patients. With relatively short follow-up of 9.1 (3-20) months we didn’t mentioned any case of grade II or more toxicity and no local recurrences. Conclusion: Our preliminary results demonstrate that combination of preoperative SABR and postoperative conventional radiotherapy is feasible and associated with low probability of grade II (and higher) toxicity.
Taxonomy, annotated new records and a checklist of Mymaridae (Hymenoptera) of Finland, with description of a new species of Eustochus
Authors: Triapitsyn Serguei V. , Koponen Martti , Vikberg Veli , Várkonyi Gergely
Published: November 2020

A taxonomic account and an annotated checklist of the Finnish Mymaridae (Hymenoptera: Chalcidoidea) are given, comprising 85 named species in 19 genera. Among them 2 genera, Dicopus Enock, 1909 and Stethynium Enock, 1909, 1 subgenus, Anagrus (Paranagrus Perkins, 1905), and the following 25 species represent new records for Finland: Anagrus (Anagrus) avalae Soyka, 1956, A. (Anagrus) bakkendorfi Soyka, 1946, A. (Anagrus) ensifer Debauche, 1948, A. (Anagrus) nigriceps (Smits van Burgst, 1914), A. (Anagrus) obscurus Förster, 1861, A. (Anagrus) parvus Soyka, 1956, A. (Anagrus) subfuscus Foerster, 1847, A. (Paranagrus) optabilis (Perkins, 1905), Anaphes (Anaphes) stygius Debauche, 1948, Camptoptera magna Soyka, 1946, Cleruchus megatrichus Novicky, 1965, C. taktochno Triapitsyn, 2014, Cosmocomoidea oxypygus (Foerster, 1856), C. tremulae (Bakkendorf, 1934), Dicopus minutissimus Enock, 1909, D. moscovit Triapitsyn, 2015, Gonatocerus aegyptiacus Soyka, 1950, Lymaenon aureus (Girault, 1911), L. longior (Soyka, 1946), Polynema flavipes Walker, 1846, P. fuscipes Haliday, 1833, P. pusilloides Debauche, 1948, P. valkenburgense Soyka, 1931, P. vitripenne (Foerster, 1847), and Stethynium triclavatum Enock, 1909. New distributional records and taxonomic notes on some genera and species are also provided. Caraphractus Walker, 1846, syn. nov. is synonymized with Eustochus Haliday, 1833 and treated as its subgenus, E. (Caraphractus), stat. revid., and its type species Caraphractus cinctus Walker, 1846 is transferred to Eustochus as Eustochus (Caraphractus) cinctus (Walker, 1846), comb. nov. Eustochus (Eustochus) koponeni Triapitsyn, sp. nov. is described from Finland and Germany. Lymaenon gracilentus (Hellén, 1974), stat. restit. is resurrected as a valid species from the previous synonymy with Lymaenon aureus and redescribed. The previously unknown male of Alaptus schmitzi Soyka, 1939 is described. Polynema depressicollis Hellén, 1974, syn. nov., is synonymized with Polynema (Doriclytus) vitripenne. Anagrus (Paranagrus) optabilis is newly recorded from the Canary Islands and Madeira, and Cleruchus megatrichus is for the first time reported from France.
Términos y Fórmulas Judiciales: Construcción de un Glosario Español - Francés. Elaboración y Proceso
Authors: Rodríguez Galán Laura
Published: November 2020

Resumen: el presente artículo muestra una visión sobre la complejidad de la traducción en el ámbito judicial con respecto al uso de glosarios terminológicos. En el marco de la Justicia es habitual que los traductores e intérpretes judiciales tengan que enfrentarse a toda clase de retos profesionales, por lo que han de estar lo suficientemente preparados, y los glosarios de terminología específica son un recurso de enorme utilidad que facilita la tarea traductora al servir de puente de comunicación entre los intermediarios de la Justicia y los ciudadanos que solicitan sus servicios (demandas, procesos judiciales, apelaciones, etc.), ya sea por vía escrita (traducción de documentos) u oral (interpretación de discursos). La principal hipótesis de la que partimos es la urgente necesidad de crear estos recursos específicos para los traductores e intérpretes que trabajan en el seno de la Justicia, y cuya carencia no hace sino incrementar las dificultades que, sin duda, estos profesionales poseen a la hora de realizar sus tareas de traducción, dada la escasa disponibilidad de tiempo para que puedan elaborar sus propios glosarios terminológicos de consulta. Con este estudio lo que se pretende es mostrar tanto las ventajas como las dificultades de la elaboración de glosarios. Por último, los resultados obtenidos confirman nuestra hipótesis de las ventajas que tiene el hecho de disponer de glosarios terminológicos específicos para el área jurídico-judicial que, sin lugar a dudas, facilitan las tareas de traducción en este ámbito de la Traducción e Interpretación en los Servicios Públicos.Abstract: the present paper shows a vision about the complexity of translation in judicial field concerning the use of terminological glossaries. In the context of Justice, it is common for judicial translators and interpreters to deal with all kinds of professional challenges. So, they must be sufficiently prepared. Glossaries of specific terminology are a resource very useful that facilitates translator’s task, by serving as a bridge of communication between intermediaries of Justice and citizens who request their services (appeals, court proceedings, lawsuits, etc.), either written (translation of documents) or oral (interpreting of speeches). The main starting hypothesis is the urgent need to create these specific resources for interpreters and translators working within the Justice, and whose lack only increases the difficulties that these professionals have, undoubtedly, when the time to perform their translation tasks, given the poor availability of time to produce their own terminological glossaries of consultation. With this study, to show advantages and difficulties of developing glossaries, that is the intention. Finally, results confirm our hypothesis of advantages to have available specific terminological glossaries in Legal-Judicial area which, undoubtedly, facilitate translation tasks in this context of Public Services Interpreting and Translation.
LEARN TO TEACH RUSSIAN AS A FOREIGN LABGUAGE
O.A. Uskova, L.N. Sahakyan
THE WORLD SPEAKS RUSSIAN (THEORETICAL AND APPLIED ASPECTS OF TEACHING RUSSIAN AS A FOREIGN LANGUAGE)
Authors: Васильева Т.В.
Published: November 2020

Учебно-методическое пособие «Мир говорит на русском (теоретические и прикладные аспекты обучения русскому языку как иностранному)», вышедшее в издательстве «Русская речь» в 2019 г., раскрывает основные положения методики преподавания РКИ. Оно актуально для широкого круга читателей: как для студентов, так и для преподавателей РКИ.

The training manual «The world speaks Russian (Theoretical and applied aspects of teaching Russian as a Foreign Language)», published by the «Russian Speech» Publishing House in 2019, provides the main methodologies of teaching Russian as a Foreign Language. This book is intended to be used by postgraduate students, who study at courses of training programs: Master degree – 04.45.02 Linguistics. Theory and practice of teaching Russian as a Foreign Language, Ph.D degree – 13.00.02 Theory of education and training (Russian as a Foreign Language), by teachers of Russian as a Foreign Language and students of continuing education and retraining programs Theory and practice of teaching Russian as a Foreign Language.
BIBLIOGRAPHY OF DR. B.R. AMBEDKAR COLLECTION INTO VIVEKANAND LIBRARY, DR. BABASAHEB AMBEDKAR OPEN UNIVERSITY, AHMEDABAD
Authors: Vyas Priyanki , Ankuya Heena
Published: November 2020

The name of Dr. B.R. Ambedkar brings to our mind a Social worker, chief architect of the Constitution of India and a founding father of The Republic of India, the messiah of backward classes and women’s rights. In this article, I have listed some famous books written by Dr. Ambedkar and also write a bibliography of collections of Vivekanand library, Dr. Babasaheb Ambedkar Open University, Ahmedabad. It is useful to find books and any materials of B.R.Ambedkar Sir. The main purpose of this article is with the use of this article, anyone can know the collection of B.R.Ambedkar Sir. More than 350 bibliographies I wrote in this article.
The Hidden Challenge: Preventive Practices of Sexually Transmitted Illness Among College Students in Western Ethiopia: The Case of Nekemte Town: A Mixed Methods Study
Authors: Feyisa BR , Cheme MC , Biru B
Published: November 2020

Objective: The study was conducted to assess the knowledge, attitude and preventive practice of college students towards Sexually Transmitted Infections (STIs) including HIV/AIDS in Nekemte town, western Ethiopia. Result: Institutional based descriptive cross sectional study design triangulated with in-depth interview method was employed on 403 randomly selected quantitative and 12 purposively selected in-depth interview samples. Quantitative data was obtained by self-administered questionnaire. About forty percent (39.7%) of the respondents had sexual practice in their life. Females were 1.42 times more likely to be encountered in sexual intercourse in the past one year of the study period (AOR = 1.42, 95% CI: 1.3, 2.53). Sex, age, living arrangement and income level, was identified as factors initiating to sexual intercourse in college students. Qualitative evidences show that, living condition, poor access of sexual reproductive services and ever increasing urbanization, poor attention towards STI are challenging preventive practices of STI among college students. Generally, college students have good awareness and positive attitude towards STIs. However, there was a wide gap between knowledge and practice of the students regarding STIs. Greater attention should be paid to the college students improving the living conditions and access of services.
Statistical Predictions of Electric Load Profiles in the UK Domestic Buildings
Authors: Ihbal A. M. , Rajamani H. S. , Abd-Alhameed R.A. , Jalboub M. K.
Published: November 2020

This paper presents a method of generating realistic electricity load profile data for the UK domestic buildings. The domestic space features have been investigated excluding the heating and hot water systems. A questionnaire survey was conducted and the feedback were collected from a number of occupants at different intervals of times on daily bases in order to establish the probabilistic record of the estimated use of electrical appliances. The model concept of this study also considers the results of previous investigations such as that available in public reports and statistics as input data elements to predict the global domestic energy consumption. In addition, the daily load profile from individual dwelling to community can be predicted using this method. The result of the present method was compared to available published data and has shown reasonable agreement.
Thoughts about the current issues of sports policing
Authors: Tóth Ágnes Nikolett
Published: November 2020

The present study investigated the causes of football hooliganism and the preliminaries, the tragic events and stadium disasters of the last few decades, which called the attention of those involved in securing these events to the fact that the existing practices had to be changed and that the creation of new legal norms was necessary. The paper showcases the significant statements in Taylor’s reports, which were adapted in the practice of securing events in Hungary, too. Taylor established that there was not one method for the management of crowd behaviour that could provide complete safety and, instead of focusing on the policing issue, he moved towards an ‘integrated’, ‘holistic’ approach. He realised that it was both impractical and impossible to stop football fans solely by criminal law measures and thought that communication with the clubs and fans, as well as with the media should be developed. All his proposals have now been implemented. Those securing sports events have been trying to ensure order as a basic value of society ever since his ideas were published.
COVID-19: What We Know So Far
Authors: Emmanuel Nancy , Zibara Victor , Saad Jean Michel , Iskandar Rita , Abi Assaad Rawad , Ammanouil Emmanuel , Bilen Yara , Chidiac Georgio , El Ahmar Nourhan
Published: November 2020

Objective: Since the emergence of the COVID-19 pandemic at the end of 2019, the number of affected cases has not stopped rising. Similarly, the number of scientific publications and pre-prints has been increasing exponentially, with an effort to understand this disease more and find a proper solution. The purpose of this article is to review the current understanding of the novel coronavirus. Background: The latest COVID-19 pandemic caused by the SARS-CoV-2 has spread globally ever since it emerged in Wuhan's city in China. This rapidly spreading disease has changed our lives in unimaginable ways, spreading fear and uncertainty due to the lack of knowledge and the flooding with new information, which lacks the scientific method and cannot be critically appraised. The purpose of this article is to gather some of the best knowledge that has been published so far in a unified narrative review, making it easy for the scientific community to review the most accurate and recent understandings about COVID-19. Methods: We screened relevant articles using a specified number of keywords and specific databases, including PubMed and Embase. We selected peer-reviewed English published material related to the topic, except for a few pre-prints that we deemed necessary to include. We also screened the reference lists of these articles to find relevant publications with the same criteria. Discussion: This narrative overview comprises several subsections that discuss the epidemiology, virology, pathogenesis, clinical manifestations, diagnostic methods, and management of the disease. We also presented a section on the implications of the disease in pregnancy. We wrapped up the review with a special division regarding the response to COVID-19,  which has been diverse in different countries. Conclusion: COVID-19 has been a serious global health threat with a high transmission and case fatality rate, particularly in vulnerable populations. Epidemiologic models have so far guided the response, but they need to be interpreted carefully, with an understanding of their limitations. The disease's response has varied among different countries; with no current vaccine or standard treatment, the world stands in fear, maximizing preventive strategies to reduce the damages caused by this virus. This manuscript presents a summary of everything that is so far known about COVID-19 to make it easier for the medical community to overview the disease that has changed the world.
New records of water scavenger beetles Berosus geminus Reiche & Saulcy, 1856 (Coleoptera: Hydrophilidae) from Russia
Authors: Sazhnev Alexey S.
Published: November 2020

The speciesBerosus geminusReiche & Saulcy, 1856 (Hydrophilidae) is recorded for the first time for European part of Russia. A map with the general distribution of this species is provided.
Aryl hydrocarbon receptors as potential therapeutic targets
Authors: Andreeva-Gateva Pavlina , Bakalov Dimitar , Sabit Zafer , Tafradjiiska-Hadjiolova Radka
Published: November 2020

Aryl hydrocarbon receptors (AhR) are regulators of the expression of cytochrome P-450 isoforms, mediating a wide variety of the effects of substances from the endogenous or exogenous origin, including those produced from the microbiome. An exciting new aspect of their activity is their localization in the brain and their potential to modulate the action of the immune system. AhR is emerging as an essential toxicological and therapeutic target for neuromodulation. Further studies are needed for elucidating their utility as drug-targets.
Chinese species of Carinostigmus Tsuneki (Hymenoptera, Crabronidae), including three new species and a new record to China
Authors: Bashir Nawaz Haider , Ma Li , Li Qiang
Published: November 2020

Three new species ofCarinostigmusTsuneki from the Oriental Region of China are described:Carinostigmus frontirugatusBashir & Ma,sp. nov.,C. latidentatusBashir & Ma,sp. nov., andC. vesulcatusBashir & Ma,sp. nov.In addition, ten species are reported, of whichCarinostigmus palawanensis(Tsuneki) is recorded in China for the first time. A key to known and new species of the genusCarinostigmusTsuneki from China is provided.
A review of Crassignatha (Araneae, Symphytognathidae)
Authors: Li Ya , Lin Yucheng , Li Shuqiang
Published: November 2020

Crassignatha Wunderlich, 1995 is redefined to include species with six eyes in three diads, chelicerae fused only near the base, sculpturing on the carapace, one or two clasping spurs on tibia II, a bilateral scutum of the male abdomen, and globular spermathecae and adjacent copulatory openings in the female. A key and distribution map are provided for 24 Crassignatha species in this paper. Diagnoses and illustrated photographs are provided for 22 species from China, Malaysia, Thailand, and Vietnam. Thirteen species are described and documented as new to science: C. baihua Y. Lin & S. Li, sp. nov. (♂♀), C. bangbie Y. Lin & S. Li, sp. nov. (♀), C. changyan Y. Lin & S. Li, sp. nov. (♀), C. dongnai Y. Lin & S. Li, sp. nov. (♀), C. gucheng Y. Lin & S. Li, sp. nov. (♂♀), C. mengla Y. Lin & S. Li, sp. nov. (♂♀), C. nantou Y. Lin & S. Li, sp. nov. (♂♀), C. nasalis Y. Lin & S. Li, sp. nov. (♂♀), C. rostriformis Y. Lin & S. Li, sp. nov. (♂♀), C. shunani Y. Lin & S. Li, sp. nov. (♂♀), C. si Y. Lin & S. Li, sp. nov. (♂♀), C. thamphra Y. Lin & S. Li, sp. nov. (♀), and C. xichou Y. Lin & S. Li, sp. nov. (♀). Three new combinations are proposed: C. bicorniventris (Lin & Li, 2009), comb. nov., C. quadriventris (Lin & Li, 2009), comb. nov., and C. shiluensis (Lin & Li, 2009), comb. nov. are transferred from Patu Marples, 1951. DNA barcodes and genetic distances of seventeen species are obtained to confirm correct identification. Types of seven known Chinese Crassignatha species are re-examined, and the taxonomic placement of C. longtou Miller, Griswold & Yin, 2009 may be incorrect based on morphological and molecular data.
Regard engagé d’un socialiste français sur les élections européennes de 2019 et la situation politique qui en est issue
Authors: Braud Maurice
Published: November 2020

Cet article examine les résultats de la famille socialiste, social-démocrate et travailliste européenne lors des élections européennes du printemps 2019. Moins spectaculaire et fort qu’annoncé, le recul électoral de cette famille politique est néanmoins important. L’auteur en propose une lecture dans le temps, en reprenant quelques étapes de la structuration européenne de cette famille politique. Outre des causes internes, ce fléchissement électoral important s’inscrit aussi dans un contexte de mutation du système politique européen, dans lequel la famille socialiste européenne et ses organisations liées ne sont pas parvenues à apparaître comme la force positive de rupture. Dans l’environnement politique européen actuel, l’auteur esquisse quelques voies susceptibles de contribuer à un regain électoral et à un rebond politique.
The Influence of the Spitzenkandidat Process on the Role of the European Political Parties
Authors: Fotopoulos Stergios , Morganti Luciano
Published: November 2020

Cet article aborde l’évolution du rôle des partis politiques européens au travers du processus des candidats têtes de liste pour la présidence de la Commission européenne (processus Spitzenkandidat), dans le but d’indiquer que la politique peut se réinscrire dans la démocratie de l’UE. Bien qu’abandonné en 2019, le processus du Spitzenkandidat a consolidé le rôle des partis politiques européens, qui sont passés de simples prestataires de services à promoteurs de campagnes électorales. Les stratégies de campagne sont passées au crible, en particulier la structure interne et les activités quotidiennes des partis politiques européens lors des campagnes de 2014 et 2019. Les données se basent sur des entretiens qualitatifs, semi-directifs et directifs, menés avec des experts au premier plan de ces campagnes, pour une approche de l’intérieur. En discutant de l’évolution du rôle des partis politiques européens et des stratégies qu’ils ont adoptées pendant les campagnes électorales, nous souhaitons réfléchir au potentiel du processus Spitzenkandidat visant à renforcer la politisation de l’UE.
EU Institutions’ Operational Resilience in the Time of COVID -19
Authors: Bodson Benjamin
Published: November 2020

La COVID-19 a interrompu le cycle décisionnel de toutes les institutions européennes. Malgré le fait que l’Union ait déjà fait face à d’importantes crises, celle-ci était imprévisible et sans précédent. Jusqu’à présent, peu d’attention a été portée sur la manière avec laquelle les institutions de l’Union ont adapté leur fonctionnement interne pour pallier aux circonstances. Cette contribution propose une analyse de ces arrangements internes. Leur analyse est importante pour des raisons démocratiques, notamment de responsabilité. De la sécurisation à la transparence des réunions virtuelles, en passant par la recherche de méthodes permettant l’adoption valide d’actes, les défis qui se sont posés aux institutions ont été majeurs. Comme cette analyse le met en lumière, certaines institutions n’étaient pas prêtes pour ces changements. De nombreuses règles doivent être adaptées, modernisées ou créées. À cet égard, la Conférence sur l’avenir de l’Europe constitue une belle opportunité de tirer les leçons de cette crise.
Dans quelle mesure l’affirmation selon laquelle « l’Europe, c’est la paix » est-elle fondée ?
Authors: Schwok René
Published: November 2020

« L’Europe, c’est la paix ». Il s’agit là d’une des formules les plus souvent mises en avant par les partisans de la construction européenne. Et pourtant, aussi étonnant que cela puisse paraître, aucune étude approfondie n’a jamais essayé d’étayer une telle affirmation. Un tel travail est d’autant plus nécessaire que le lien entre “intégration européenne” et “paix” est désormais fortement contesté, particulièrement avec l’ascension de forces opposées à la construction européenne. L’objectif de cet article est de renouveler l’argumentation sur ce sujet. Pour ce faire, il n’hésite pas à contester certains poncifs véhiculés par les européistes (pro-Européens), tout en incorporant de manière dialectique certaines des objections avancées par l’approche eurosceptique.
L’enjeu pour la Tunisie du libre-échange avec l’Union européenne
Authors: Boudhiaf Messaoud
Published: November 2020

Cet article examine les avantages et les inconvénients de l’intégration d’un petit pays dans un grand espace économique. Il tente d’analyser les gains et les pertes des accords d’intégration commerciale établis entre la Tunisie et l’Union européenne. Il discute aussi le récent projet intitulé Accord de Libre-Échange Complet et Approfondi (ALECA) proposé par l’UE à la Tunisie. Bien que l’impact de l’intégration soit indéterminé, ses gains sont importants et ses risques sont évitables grâce à une politique commerciale adaptée.
Mobilisation de la violence armée dans la sécurisation foncière
Authors: M’munga Assumani François
Published: November 2020

Cet article analyse le phénomène de la sécurisation foncière par la violence armée au moment de l’éclatement des conflits fonciers en province du Sud-Kivu, en République démocratique du Congo, dans un contexte caractérisé par la déliquescence de l’État congolais. À partir de deux cas de conflits fonciers, cet article révèle que les acteurs locaux recourent souvent aux forces armées nationales, aux groupes armés locaux et/ou aux acteurs eux-mêmes qui se sont armés pour sécuriser leurs terres. De fait, loin de la conception nocive de la violence armée, les stratégies et logiques d’action des acteurs attestent que la violence armée peut être considérée comme une des normes pratiques dans la sécurisation des droits fonciers en milieu coutumier, quelle que soit leur nature.
Improvement of finite-time stability for delayed neural networks via a new Lyapunov-Krasovskii functional
Authors: Prasertsang Patarawadee , Botmart Thongchai
Published: November 2020

The topic of finite-time stability criterion for neural networks with time-varying delays via a new argument Lyapunov-Krasovskii functional (LKF) was proposed and the time-varying delay of the system is without differentiable. For sufficient conditions of this study, a new (LKF) is combined with improved triple integral terms, namely the functionality of finite-time stability, integral inequality, and a positive diagonal matrix without using a free weighting matrix. The improved finite-time sufficient conditions for the neural network with time varying delay are given in terms of linear matrix inequalities (LMIs) and the results show improvement on previous studies. Numerical examples are given to illustrate the effectiveness of the proposed method.
La problématisation : une entrée pour examiner et repenser l’apprentissage des élèves en éducation physique et sportive à l’école maternelle
Authors: Véjux-Grillot Marine
Published: November 2020

Cet article rend compte d’une approche collaborative menée dans trois classes de grande section (GS) de maternelle. L’étude met en relation des enseignants du premier degré et un chercheur collaborant autour d’une « situation forcée » (Orange, 2010) en sports collectifs. La situation repose sur une alternance « mise en activité - débat - mise en activité » pour les élèves. L’objectif étant que ces derniers problématisent à partir d’un obstacle rencontré en situation afin de le dépasser et de transformer leur activité tactico-technique. La capacité des élèves de maternelle à problématiser de même que l’impact de l’activité de problématisation dans la construction d’apprentissages moteurs en éducation physique et sportive (EPS) sont examinés dans cette étude.
Baseline characteristics and outcomes of COVID-19 patients admitted to a Respiratory Intensive Care Unit (RICU) in Southern Italy
Authors: Di Lecce Valentina , Carpagnano Giovanna Elisiana , Pierucci Paola , Quaranta Vitaliano Nicola , Barratta Federica , Zito Annapaola , Buonamico Enrico , Resta Onofrio
Published: November 2020

The recent Coronavirus disease 19 (COVID-19) pandemic, first in China and then also in Italy, brought to the attention the problem of the saturation of Intensive Care Units (ICUs). Almost all previous reports showed that in ICU less than half of patients were treated with invasive mechanical ventilation (IMV) and the rest of them with non-invasive respiratory support. This highlighted the role of respiratory intensive care units (RICUs), where patients with moderate to severe respiratory failure can be treated with non-invasive respiratory support, avoiding ICU admission. In this report, we describe baseline characteristics and clinical outcomes of 97 patients with moderate to severe respiratory failure due to COVID-19 admitted to the RICU of the Policlinico of Bari from March 11th to May 31st 2020. In our population, most of the subjects were male (72%), non-smokers (76%), with a mean age of 69.65±14 years. Ninety-one percent of patients presented at least one comorbidity and 60% had more than two comorbidities. At admission, 40% of patients showed PaO2/FiO2 ratio between 100 and 200 and 17% showed Pa02/FiO2 ratio <100. Mean Pa02/FiO2 ratio at admission was 186.4±80. These patients were treated with non-invasive respiratory support 40% with CPAP, 38% with BPAP, 3% with HFNC, 11% with standard oxygen therapy or with IMV through tracheostomy (patients in step down from ICU, 8%). Patients discharged to general ward (GW) were 51%, 30% was transferred to ICU and 19% died. To the best of our knowledge, this is one of the few described experiences of patients with respiratory failure due to COVID-19 treated outside the ICU, in a RICU. Outcomes of our patients, characterized by several risk factors for disease progression, were satisfactory compared with other experiences regarding patients treated with non-invasive respiratory support in ICU. The strategical allocation of our RICU, between ED and ICU, might have positively influenced clinical outcomes of our patients.
Spectrum and Evolution of EEG Changes in Anti-NMDAR Encephalitis
Authors: Viswanathan Lakshminarayanapuram Gopal , Siddappa Shreedhara A. , Nagappa Madhu , Mahadevan Anita , Duble Shishir , Bindu Parayil S , Taly Arun B , Sinha Sanjib
Published: November 2020

Background:

NMDA receptor encephalitis (NMDARE) is the most prevalent autoimmune encephalitis and it encompasses a spectrum of clinical features. It is most commonly associated with alteration in consciousness, seizures, neuro-psychiatric symptoms, and movement disorders. Electroencephalography (EEG) plays a vital role and can give clues to diagnosis in a subset of patients.

Methods:

We retrospectively characterized the clinical and EEG findings in our NMDARE patients (n = 48). A total of 131 EEGs were analyzed.

Results:

We observed that patients with seizures had a younger age of onset (p < 0.001). The most common EEG pattern that was noted was diffuse slowing (n = 20) followed by generalized rhythmic delta activity (n = 9), focal spikes and slowing (n = 8 each). Delta brush pattern was seen in only 3 EEGs. Focal ictal rhythms were seen in 3 EEGs. There was no significant difference in outcomes such as seizure recurrence, modified Rankin score (mRS) at follow up/discharge or relapse between groups of patients who had EEG abnormalities in the first EEG and with those who did not.

Conclusions:

NMDARE has varied EEG findings, most of them being non-specific. When combined with clinical presentation, EEG is a useful tool in the diagnosis and management of NMDARE.
Prognostic value of ECOG performance status and Gleason score in the survival of castration-resistant prostate cancer
Authors: Chen Wen-Jun , Kong Da-Ming , Li Liang
Published: November 2020

Eastern Cooperative Oncology Group (ECOG) performance status and Gleason score are commonly investigated factors for overall survival (OS) in men with castration-resistant prostate cancer (CRPC). However, there is a lack of consistency regarding their prognostic or predictive value for OS. Therefore, we performed this meta-analysis to assess the associations of ECOG performance status and Gleason score with OS in CRPC patients and compare the two markers in patients under different treatment regimens or with different chemotherapy histories. A systematic literature review of monotherapy studies in CRPC patients was conducted in the PubMed database until May 2019. The data from 8247 patients in 34 studies, including clinical trials and real-world data, were included in our meta-analysis. Of these, twenty studies reported multivariate results and were included in our main analysis. CRPC patients with higher ECOG performance statuses (≥ 2) had a significantly increased mortality risk than those with lower ECOG performance statuses (<2), hazard ratio (HR): 2.10, 95% confidence interval (CI): 1.68–2.62, and P < 0.001. The synthesized HR of OS stratified by Gleason score was 1.01, with a 95% CI of 0.62–1.67 (Gleason score ≥ 8 vs <8). Subgroup analysis showed that there was no significant difference in pooled HRs for patients administered taxane chemotherapy (docetaxel and cabazitaxel) and androgen-targeting therapy (abiraterone acetate and enzalutamide) or for patients with different chemotherapy histories. ECOG performance status was identified as a significant prognostic factor in CRPC patients, while Gleason score showed a weak prognostic value for OS based on the available data in our meta-analysis.
Retrospective analysis of the changes in the surgical treatment of benign prostatic hyperplasia during an 11-year period
Authors: Peng Zhu-Feng , Zhou Jing , Song Pan , Yang Lu-Chen , Yang Bo , Ren Zheng-Ju , Wang Lin-Chun , Wei Qiang , Dong Qiang
Published: November 2020

The present study aimed to determine whether the number of patients with symptomatic benign prostatic hyperplasia (BPH) who preferred surgery decreased during the past 11 years at our center (West China Hospital, Chengdu, China), and whether this change affected the timing of surgery and the physical condition of surgical patients. This retrospective study included 57 557 patients with BPH treated from January 2008 to December 2018. Of these, 5427 patients were treated surgically. Surgical patients were divided into two groups based on the time of treatment (groups 8–13 and groups 13–18). The collected data comprised the percentage of all patients with BPH who underwent surgery, baseline characteristics of surgical patients, rehabilitation time, adverse events, and hospitalization costs. The surgery rates in groups 8–13 and groups 13–18 were 10.5% and 8.5% (P < 0.001), respectively. The two groups did not clinically differ regarding patient age and prostate volume. The rates of acute urinary retention and renal failure decreased from 15.0% to 10.6% (P < 0.001) and from 5.2% to 3.1% (P < 0.001), respectively. In groups 8–13 and groups 13–18, the mean catheterization times were 4.0 ± 1.7 days and 3.3 ± 1.6 days (P < 0.001), respectively, and the mean postoperative hospitalization times were 5.1 ± 2.4 days and 4.2 ± 1.8 days (P < 0.001), respectively. The incidences of unplanned second surgery and death reduced during the study period. The surgery rate decreased over time, which suggests that medication was chosen over surgery. However, the percentage of late complications of BPH also decreased over time, which indicates that the timing of surgery was not delayed.
Chẩn đoán trước bất thường nhiễm sắc thể ở thai mắc tim bẩm sinh liên quan đến quá trình ngăn thân động mạch – nón tim
Authors: Bùi Hải Nam , Trần Danh Cường , Nguyễn Thị Hiệp Tuyết
Published: November 2020

Mục tiêu: Mô tả bất thường nhiễm sắc thể (NST) liên quan đến bất thường quá trình ngăn thân động mạch – nón tim được chẩn đoán trước sinh.

Đối tượng và phương pháp nghiên cứu: mô tả cắt ngang 109 thai được chẩn đoán dị tật tim bẩm sinh (TBS) liên quan đến quá trình ngăn thân động mạch – nón tim trên siêu âm, được chọc hút dịch ối, sử dụng kỹ thuật BoBs và Karyotype để phân tích NST thai.

Kết quả: Các loại dị tật TBS liên quan đến quá trình ngăn thân động mạch – nón: Tứ chứng fallot (63/109 - 57,8%), chuyển chỗ mạch máu lớn (18/109 - 16,5%), hẹp động mạch phổi (10/109 – 9,2%), thất phải hai đường ra (5/109 – 4,6%), thân chung động mạch (2/109 – 1,8%) và các loại bất thường khác liên quan đến động mạch chủ, thất trái (11/109 – 10,1%). Tỷ lệ bất thường NST là 33/109 (30,3%), bất thường về số lượng NST là 14/33 trường hợp và bất thường về cấu trúc NST là 19/33 trường hợp (13 trường hợp hội chứng DiGeorge). Nhóm có bất thường phối hợp cơ quan khác ngoài tim có nguy cơ NST bất thường cao hơn 7.3 lần so với nhóm chỉ có biểu hiện bất thường tại tim, OR = 7.3 (2.6; 20.5), p = 0.0002.

Kết luận: Các loại dị tật tim bẩm sinh liên quan đến quá trình ngăn thân động mạch là các dị tật nặng, thai bất thường NST ở nhóm dị tật này chiếm tỷ lệ cao, trong đó hội chứng DiGeorge chiếm phần lớn.
Peranan Sistem Penilaian CAVeA2T2 dalam Memprediksi Maturasi Fistula Radiosefalika
Authors: Andhini Ratna Astri , Djajakusumah Teguh Marfen , Hapsari Putie , Nusjirwan Rama
Published: November 2020

Latar Belakang. Berdasarkan panduan National Kidney Foundation-Kidney Disease Outcomes Quality Initiative (NKF/KDOQI), fistula radiosefalika merupakan pilihan utama akses vaskular pada pasien yang menjalani hemodialisis. Fistula dikatakan matur apabila sesuai dengan rule of six (laju aliran >600mL/menit, diameter ?6mm dan berjarak sekitar ?6mm dari permukaan kulit). Sistem penilaian CAVeA2T2 (akses vena sentral ipsilateral, usia >73 tahun, vena <2,2mm, riwayat angioplasty pada tungkai bawah, dan tidak ditemukannya thrill intraoperatif) memiliki potensi dalam menilai maturasi fistula radiosefalika.

Metode. Desain analitis menggunakan metode kohort prospektif dengan consecutive sampling untuk menilai perananan sistem penilaian CAVeA2T2 dalam memprediksi maturasi fistula radiosefalika. Populasi terjangkau adalah pasien gagal ginjal terminal (GGT) yang datang ke poliklinik Bedah Vaskular RSUP Dr. Hasan Sadikin Bandung dan RSKG Ny.R.A.Habibie yang akan menjalani operasi fistula radiosefalika. Uji statistik menggunakan uji univariat untuk dekskripsi data. Sampel dikelompokkan berdasarkan skor CAVeA2T2 (skor <2 dan ?2) dan status maturasi fistula (matur/non matur) kemudian dianalisis melalui perbandingan antar kelompok melalui model bivariat. Selanjutnya analisis untuk menguji hipotesis melalui analisis Chi-Square Fisher dengan batas kemaknaan 0,05.

 Hasil. Didapatkan 24 pasien (perbandingan laki-laki dan perempuan adalah 1:1) yang dilakukan analisis dengan rentang usia 21-76 tahun, rerata tekanan sistolik 149,2 (±28,4) mmHg. Didapatkan sitem penilaian CAVeA2T2 memiliki peranan dalam memprediksi maturasi fistula radiosefalika dengan probabilitas kesalahan statistik sebesar p<0,01 dan koefisien kontingensi sebesar C=0,674. Derajat peranan sistem penilaian CAVeA2T2 terhadap maturasi fistula radiosefalika tergolong sangat kuat berdasarkan klasifikasi Guilford.

Kesimpulan. Sistem penilaian CAVeA2T2 memiliki peranan dalam memprediksi maturasi fistula radiosefalika.

(ISSN 2723-7494 J Bedah Indonesia. 2020;48:15-37)
Hubungan Kadar Laktat dan Albumin dengan Mortalitas dan Morbiditas Pasien Perforasi Ulkus Peptikum
Authors: Karina Gisela , Rudiman Reno , Ruchimat Tommy
Published: November 2020

Latar Belakang. Perforasi ulkus peptikum merupakan kondisi emergensi di seluruh dunia, dengan tingkat mortalitas sampai dengan 30%. Penilaian kadar laktat dan albumin dalam darah diharapkan dapat menjadi suatu perangkat penilai untuk memperkirakan tingkat mortalitas dan morbiditas pasien perforasi ulkus peptikum.3,5

Metode. Desain analitis menggunakan metode kohort prospektif dengan analisis korelasi hubungan kadar albumin dan laktat terhadap kejadian mortalitas dan morbiditas pasien perforasi ulkus peptikum di RS. Hasan Sadikin. Subjek penelitian dilakukan dengan cara consecutive sampling. Populasi terjangkau adalah pasien dengan diagnosis klinis perforasi ulkus peptikum yang datang ke Unit Gawat Darurat RSHS pada periode 1 Februari 2018 – 28 Februari 2019. Uji statistik menggunakan uji analisis regresi logistik bivariat.

Hasil. Didapatkan 40 pasien, mayoritas berjenis kelamin laki – laki (35 pasien), sisanya perempuan dengan rentang usia 22 – 80 tahun. Didapatkan 11 pasien meninggal (27.5% dari sampel). Pasien mati memiliki rata – rata kadar laktat 6,4 ± 3,7 mmol/L dan rata – rata kadar albumin 2,1 ± 0,4 mg/dL. Morbiditas pada penelitian ini ialah komplikasi hospital acquired pneumonia pasca operasi. Hasil uji Wald membuktikan bahwa kadar laktat berhubungan positif secara signifikan dengan mortalitas pasien perforasi ulkus peptikum dengan probabilitas kesalahan statistik sebesar p = 0,024 (p < 0,05) dan kadar albumin berhubungan negatif secara signifikan dengan mortalitas pasien perforasi ulkus peptikum dengan probabilitas kesalahan statistik sebesar p = 0,032 (p < 0,05).

Kesimpulan: Kadar laktat berhubungan positif dengan mortalitas pasien namun tidak dengan morbiditas pasien, sedangkan kadar albumin berhubungan negatif dengan mortalitas pasien namun tidak dengan morbiditas pasien.. Semakin tinggi kadar laktat dan semakin rendah kadar albumin, semakin tinggi probabilitas pasien untuk mati.
YARATICI TAKIM İKLİMİ ÖLÇEĞİ: TÜRKÇE’YE UYARLAMA, GEÇERLİLİK VE GÜVENİRLİK ÇALIŞMASI
Authors: PEKKAN Nazmiye Ülkü , ÇALIŞKAN Abdullah
Published: November 2020

Bu araştırmanın amacı, Yaratıcı Takım İklimi Ölçeğinin Türkçe uyarlamasını yapmaktır. Özellikle yeni dünya düzeninde, örgütlerin rekabet sürecini başarılı bir şekilde yönetmesinin altında bireylerin ve takımların yaratıcı eylem ve düşüncelerinin önemli bir rolü olması nedeniyle, tüm sektörlerde yaygın olarak kullanılabilecek Yaratıcı Takım İklimi Ölçeğinin Türk kültüründe değerlendirilmesi önemli görülmüştür. Türkçe literatürde söz konusu ölçeğin geçerlemesini test eden bir çalışmaya rastlanmamıştır. Araştırmanın çalışma grubuna Mersin ve Ankara illerindeki iki farklı sektörün çalışanları dahil edilmiştir. Analizler neticesinde söz konusu ölçeğin orijinal ölçekle uyum gösterdiği ve Türkiye’deki farklı sektörler üzerinde yaratıcı takım iklimi algısının ölçülmesinde güvenilir bir ölçme aracı olduğuna dair güçlü kanıtlara ulaşılmıştır.
SOSYAL MEDYA’DA ÇOCUK MAHREMİYETİ: EBEVEYNLERİN INSTAGRAM’DAKİ ÇOCUK MAHREMİYETİNE BAKIŞ AÇILARI
Authors: SEZERER ALBAYRAK Eda
Published: November 2020

Dijital dünyanın içerisinde kaybolunan bu dönemde dünyaya dijital ekranların arkasından bakıldığı inkâr edilemeyen bir gerçektir. Bu dijital dünyada en çok eleştirilen, üzerinde konuşulan ama bir o kadar da vazgeçilmez olan sosyal medya kullanımı sonucunda ister istemez belli tavizler verilmektedir. Bireyler hem kendilerinin hem de çocuklarının fotoğraflarını, videolarını, mahrem bilgilerini paylaşmaktadırlar. Çocukların mahremiyeti özellikle son zamanlarda çok fazla konuşulmaya başlanmıştır. Çocuklar genellikle ilk adımlarını atmadan çok önce dijital ayak izlerine sahip olmaktadırlar. Uzman kaynaklar, en başta ebeveynlerin sosyal medyayı anlamaları, dijital medya okuryazarı olmaları, çocuklarına yönelik paylaşım yaparken pedofili, çocuk istismarı vb. konularının farkında olarak içerik oluşturmalarını söylemektedirler. Çocuklarının günlük yaşantılarının neredeyse hepsini sosyal medya mecralarından yayınlayan ebeveynler için farkındalık yaratmak adına çalışma önem arz etmektedir. Instagram hesabını aktif olarak kullanan ebeveynlerin çocuk mahremiyeti konusundaki bakış açılarını ortaya koymayı amaçlayan bu çalışma Konya ilinde yaşayan 20 katılımcı ile yarı yapılandırılmış yüz yüze görüşme gerçekleştirilerek veriler toplanmıştır. Bu veriler nitel veri analizi ile incelenmiş olup sonuca ulaşılmıştır.
Comparative evaluation of upper versus lower calyceal approach in percutaneous nephrolithotomy (1) for managing renal calculi
Authors: Waqar Ahmed Memon  , Salman El Khalid  , Ali Haider  , Sherjeel Saulat  , Shariq Anis Khan  , Muhammad Bilal Quddus  , Khadijah Abid
Published: November 2020

Abstract

Objective: To compare upper versus lower calyceal approaches in percutaneous nephrolithotomy for managing renal calculi.

Method: The retrospective study was conducted in the Department of Urology, The Kidney Centre Post-Graduate Training Institute, Karachi, and comprised data of patients who underwent percutaneous nephrolithotomy from January 2014 to January 2015. Patients were divided into upper pole puncture group A and lower pole puncture group B. Data was analysed using SPSS 17.

Results: Of the 198 patients, 147(74.2%) were males and 51(25.8%) were females. The overall mean age was 40.64±14.02 years. Of the total, 69(34.84%) were in group A and 129(65.15%) were in group B. Inter-group difference was significant in pre- and post-operative haemoglobin (p<0.05). Post-operative outcomes showed that blood transfusion, stone clearance and complication like tube thoracostomy had significant association with both the groups (p<0.05). Complete clearance was seen in 152(76.8%) patients; 40(74.1%) in group A and 102(81.6%) in group B.

Conclusion: The success rate was found to be better in lower calyceal puncture group than upper calyceal puncture group for the management of renal calculi.

Key Words: Upper and lower calyceal approach, Percutaneous nephrolithotomy, Continuous....
PLASMAPHERESIS IN PATIENT WITH GUILLAIN-BARRE SYNDROME OF THE INTENSIVE CARE UNIT
Authors: Ramdhani Vicky Muhammad , Suwarman K , Sudjud Reza Widianto , Pradian Erwin
Published: November 2020

Purpose: The purpose of writing this case report is to determine the importance of patient treatment using appropriate and specific therapies and the use of mechanical ventilation in the threat of respiratory failure of patients with GBS.

Methodology: We presented a case of 47 years old man with chief complaint of weakness in both upper and lower extremities. The patient was diagnosed with GBS and plasmapheresis was performed.

Findings: Holistic intensive care together with plasmapheresis has been shown to improve the survival of patients with GBS. In the current study, the patient was admitted for 1 day in HCU before he experienced difficulty in breathing, was intubated, and transferred to ICU. Plasmapheresis was performed six times in the ICU. The patient progressively improved until he was discharged to the HCU on 10th day of ICU admission.

Unique contribution to theory, practice, and policy: Holistic intensive care together with plasmapheresis has been shown to improve the survival of patients with GBS. From the current study, we recommend healthcare practitioners to perform either IVIG therapy or plasmapheresis for GBS patient
Job Burnout in Front-Line Employees: Moderating Role of Hope and Self-Efficacy
Authors:   University of Central Punjab, Akhtar Faiza , Khan Huma
Published: November 2020

The present study investigates the effects of burnout toward job performance and job satisfaction with a moderating role of hope and self-efficacy. Findings from 310 frontline employees of Pakistani commercial bank (Lahore, Karachi & Islamabad), showed burnout has a significant negative effect on job performance and job satisfaction. A simple random sampling technique was used to collect data, and inferential statistics were applied to analyze the data. However, results disclose no moderation effect of hope on burnout and job performance or with job satisfaction. But, data significantly support the moderation effect of self-efficacy. The moderation effect was analyzed by the moderation process of Preacher, Rucker, & Hayes, (2007). The study further sheds light on the development of psychological capital, and the importance of the implication of the current finding is discussed. This study will help top management and trainers to understand so they can manage burnout issues on frontline employees for better performance and employee satisfaction.
Wild Life
Authors: Baid Anisha
Published: November 2020

Wild Life is a series of augmented photographs of animals and insects placed in vacant, overgrown spaces in suburban Bangalore. Taken through mobile AR apps like Holo and Augment, these photographs (or screenshots) situate virtual bodies within the frame of the mobile camera – creating something in between a document and fiction. The work investigates these processes of augmentation, which enable 3D representations of things in the real/physical world to be projected back into physical space that are then photographed. The larger phenomenon of AR photography also complicates traditional notions of “immersive” media – forcing one to interact with their environments. This essay reflects on the implications of mobile AR photography on the image and the referent. Through a phenomenological reading of and immersion into popular uses of mobile AR (like the game Pokémon Go), the essay is an observation of the convoluted relationships evoked between augmented bodies, their environments and the screens on which they manifest. Keywords: digital image, documentary, mobile AR, photography, Pokémon Go