bluuebunny/crossref_metadata_2025 huggingface dataset:
Early Identification of Autism Spectrum Disorder: Recommendations for Practice and Research
Authors: Zwaigenbaum Lonnie , Bauman Margaret L. , Stone Wendy L. , Yirmiya Nurit , Estes Annette , Hansen Robin L. , McPartland James C. , Natowicz Marvin R. , Choueiri Roula , Fein Deborah , Kasari Connie , Pierce Karen , Buie Timothy , Carter Alice , Davis Patricia A. , Granpeesheh Doreen , Mailloux Zoe , Newschaffer Craig , Robins Diana , Roley Susanne Smith , Wagner Sheldon , Wetherby Amy
Published: October 2015

Early identification of autism spectrum disorder (ASD) is essential to ensure that children can access specialized evidence-based interventions that can help to optimize long-term outcomes. Early identification also helps shorten the stressful “diagnostic odyssey” that many families experience before diagnosis. There have been important advances in research into the early development of ASDs, incorporating prospective designs and new technologies aimed at more precisely delineating the early emergence of ASD. Thus, an updated review of the state of the science of early identification of ASD was needed to inform best practice. These issues were the focus of a multidisciplinary panel of clinical practitioners and researchers who completed a literature review and reached consensus on current evidence addressing the question “What are the earliest signs and symptoms of ASD in children aged ≤24 months that can be used for early identification?” Summary statements address current knowledge on early signs of ASD, potential contributions and limitations of prospective research with high-risk infants, and priorities for promoting the incorporation of this knowledge into clinical practice and future research.
Early Intervention for Children With Autism Spectrum Disorder Under 3 Years of Age: Recommendations for Practice and Research
Authors: Zwaigenbaum Lonnie , Bauman Margaret L. , Choueiri Roula , Kasari Connie , Carter Alice , Granpeesheh Doreen , Mailloux Zoe , Smith Roley Susanne , Wagner Sheldon , Fein Deborah , Pierce Karen , Buie Timothy , Davis Patricia A. , Newschaffer Craig , Robins Diana , Wetherby Amy , Stone Wendy L. , Yirmiya Nurit , Estes Annette , Hansen Robin L. , McPartland James C. , Natowicz Marvin R.
Published: October 2015

This article reviews current evidence for autism spectrum disorder (ASD) interventions for children aged <3 years, based on peer-reviewed articles published up to December 2013. Several groups have adapted treatments initially designed for older, preschool-aged children with ASD, integrating best practice in behavioral teaching methods into a developmental framework based on current scientific understanding of how infants and toddlers learn. The central role of parents has been emphasized, and interventions are designed to incorporate learning opportunities into everyday activities, capitalize on “teachable moments,” and facilitate the generalization of skills beyond the familiar home setting. Our review identified several comprehensive and targeted treatment models with evidence of clear benefits. Although some trials were limited to 8- to 12-week outcome data, enhanced outcomes associated with some interventions were evaluated over periods as long as 2 years. Based on this review, recommendations are proposed for clinical practice and future research.
Modern information tools: their place in students’ extra-curriculum and involvement of them in motor activity of health related orientation
Authors: Yurchyshyn Y.V.
Published: October 2015

Purpose: to determine place and role of modern information tools in formation of motivation for health related motor functioning. Material: in the research 150 boys and 150 girls participated. All they were questioned. Results: we have determined that in hierarchy of students’ functioning in extra-curriculum time its general kinds prevail. Special kinds of health related motor functioning take unfairly low position. Among general kinds of functioning Internet dominates. We found that health related motor functioning takes low position in general hierarchy: only 2 % of girls and 5.3 % of boys use it in form of training of favorite kind of sports; accordingly 8% and 6 % - in the form of walks in the open air. Conclusions: it is necessary to uses students’ preferences of Internet for their involvement in health related motor functioning.
Microstructural, Mechanical Properties and Corrosion Resistance of Ferritic Stainless Steel Welded by GTAW and Coated by Flame Spraying
Authors: Delgado-Venegas J. , Molina-Díaz A. , Ambriz-Rojas R.R. , Cuenca-Álvarez R.
Published: October 2015

Ferritic stainless steels are widely used in transportation industry due to their exceptional performance regarding mechanical and corrosion properties. However, after a welding process, joints feature the sensitizing phenomenon because of the heat exchange from the torch affecting mechanical properties and corrosion resistance. This work describes the behavior firstly of mechanical properties of weld joints of ferritic stainless steel as base material without and with filler material (AISI 308L) by gas tungsten arc welding (GTAW). Operating parameters such as arc voltage, welding currrent, welding speed, feed speed, shielding gas flow were evaluated. Secondly, samples of weld joints were coated by flame spraying of composite particles in order to reduce the weight loss induced by corrosion in a salt spray (fog) apparatus. Changes induced from GTAW on the heat affected zone and Thermal Spraying on corrosion resistance, were monitored by optical and scanning electron microscopy, microhardness and longitudinal tensile testing. Results show that GTAW helps to control the size and the microstructure of heat affected zone improving simultaneously the mechanical properties. Meanwhile, welded joints covered by composite coatings feature a lower damage provided that the ceramic phase has been homogeneously dispersed.
Principles of Technology and Mechanical Properties of Structural Ceramics Based on the Ternary System SiC–B4C–CrB2
Authors: Chalgin Aleksei V. , Vikhman Sergei V. , Ordan’yan Sukyas S. , Danilovich Dmitry P. , Nechaeva Maria V.
Published: October 2015

The aim of this research was to work out the technology of ceramics for finding optimal sintering temperatures and to study their mechanical properties. Samples were prepared from powders with different volumetric ratio of the components. The powders underwent a prolonged co-milling in a vibratory mill, followed by uniaxial pressing, cold isostatic pressing (CIP) and pressureless sintering in a vacuum furnace under an argon atmosphere. Hot pressing (HP) was applied to some powder formulations. This study showed that it is advisable to carry out the first stage of the heat treatment up to 1550 ̊C under vacuum, with the aim of refining the grain surface from the oxygen-containing impurities due to their dissociation and evaporation. The studied area of formulations has a very narrow range of sintering (1940-1945 ̊C). It was established that the sinterability of the materials is affected by the amount of silicon carbide in the ternary system. Under pressureless sintering, the relative density of the material directly depended on the volume fraction of SiC. However, a change in the concentration of B4C had no appreciable effect on the sinterability of the materials. The application of HP helped us to reduce the negative impact of large amounts of SiC. Under HP at temperatures close to Teut, a certain decompaction of materials was observed with a significant amount of B4C (3-5% loss in density).
Numerical Analysis Applied to Nonlinear Problems
Authors: León E. Pineda , Rodríguez-Castellanos A. , Aliabadi M.H.
Published: October 2015

The present paper shows the applicability of the Dual Boundary Element Method to analyze plastic, visco-plastic and creep behavior in fracture mechanics problems. Several models with a crack, including a square plate, a holed plate and a notched plate are analyzed. Special attention is taken when the discretization of the domain is done. In Fact, for the plasticity and viscoplasticity cases only the region susceptible to yielding was discretized, whereas, the creep case required the discretization of the whole domain. The proposed formulation is presented as an alternative technique to study this kind of non-linear problems. Results from the present formulation are compared to those of the well-established Finite Element Technique, and they are in good agreement. Important fracture mechanic parameters such as KI, KII, J- and C- integrals are also included. In general, the results, for the plastic, visco-plastic and creep cases, show that the highest stress concentrations are in the vicinity of the crack tip and they decrease as the distance from the crack tip is increased.
Ceramic Refractory Compositions with Biosolubility Characteristics
Authors: Joaquín-Morales Ma.G. , Vargas-Gutiérrez G. , Rodríguez-Galicia J.L. , Vazquez-Carbajal G.I. , López-Cuevas J.
Published: October 2015

In this work, we studied the dissolution of three different refractory compositions belonging to the ternary system SiO2-CaO-MgO into two Simulated Lung Fluids (SLF). The initial powder mixtures were uniaxially pressed and then sintered at 1300-1400 °C. The sintered samples were immersed for times from 1 to 21 days into a given SLF at 37 °C. The samples were characterized by X-Ray Diffraction (XRD) and Scanning Electron Microscopy (SEM). The dissolution of Ca2+, Mg2+ and Si4+ into the SLF was quantified by Inductively Coupled Plasma Atomic Emission Spectroscopy (ICP-AES). The in vitro studies suggested that all the considered materials had a potential to show a diminished biopersistence in vivo, due to reasons that depended on their chemical and phase composition.
Influence of Heat Treatments on a NiTi Shape Memory Alloy Obtained Using Vacuum Induction Melting and Reprocessed by Plasma Skull Push-Pull
Authors: de Brito Simões Jackson , Pereira Francisco Fernando Roberto , Otubo Jorge , de Araújo Carlos José
Published: October 2015

Shape memory alloys (SMA) are metallic attractive engineering materials due to their capacity to store pre-defined shapes through a thermally induced phase transition from a solid state. This paper aims to evaluate the influence of solubilization thermal treatments on a NiTi shape memory alloy originally fabricated by vacuum induction melting and then reprocessed by plasma melting followed by injection molding (Plasma Skull Push Pull process) into different metal molds (steel, aluminum, brass and copper) in order to compare the thermal properties regarding to its raw state. The thermal treatments of solubilization were carried out at 850°C in different times (2n function, n = 0, 1, 2 and 3, in hours). The influence of solubilizing treatments in the NiTi shape memory alloy was analyzed using the following characterization techniques: Differential Scanning Calorimetry (DSC) and Electrical Resistance as a function of Temperature (ERT). The results demonstrate that the solubilization heat treatments applied on the reprocessed NiTi shape memory alloy through the plasma skull push pull process, provides important changes in the phase transformation of the material. Therefore, it was demonstrated that it is necessary to solubilize the material after melting or remelting the NiTi shape memory alloy via this process to obtain mini-actuators products with homogeneous properties.
Determination of Recrystallization Kinetics and Activation Energy of Grain Growth Process of Cu-14Al-4Ni Shape Memory Alloy
Authors: Lima Emmanuel P. R. , de Lima Pedro C. , Nava Marcelo
Published: October 2015

The non-ferrous shape memory alloys have, normally, two problems that hinder its use in industrial scale: the natural aging and grains growth. The first degrades the memory effect, while the second, observed during the processing of alloy, modifies the temperatures which the transformations occur. Thus, the study of kynetic of recrystallization is important for enabling the control of hardened state in function of treatment time, without causing excessive grain growth. Therefore, the objective of this study is to determine the kinetics of recrystallization of Cu-14Al-4Ni shape memory alloy, based on an empirical law of the formation of Jonhson-Mehl-Avrami, as well as their activation energies for grain growth process according to the empirical Arrhenius law. The alloy was vacuum melted in an induction furnace. After casting, the bulk samples of the alloy were homogenized for 24 hours, solubilized and hot rolled followed by water-quenching to initiate the recrystallization. Then, different samples were annealed at temperatures close to the peak, start and end of the DSC curve. Following the heat treatments, the samples were submitted to mechanical tests and the values of the properties were correlated to the fraction transformed for determination of recrystallization’s kinetic. For the characterization of the grain growth process, analyses in optical microscopy were accomplished and all annealed samples were examined by statistical metallography and the grain sizes were measured. After measurements, the ln[-ln(1-Yrec)] x ln(t) and the ln [D-Do] x 1/T diagrams were plotted to determine the parameters of Jonhson-Mehl-Avrami equation and the activation energy of the process, respectively. The results showed that the equation of the recrystallized fraction follows the empiric law of the formation of Jonhson-Mehl-Avrami for the considered property, as well as, also showed that the alloy Cu-14Al-4Ni is extremely sensitive to temperature variation in which the alloy is treated, having a dual kinetics of grain growth. In the first domain, between 670 and 710°C, the diagram provides a value for the activation energy equal to 39.32 KJ/mol, in the second domain, between 710 and 790°C, the diagram provides a value for the activation energy equal to 9.01 KJ/mol.
Experimental and Theoretical Study on Melting Kinetics of Spherical Aluminum Particles in Liquid Aluminum
Authors: Ramírez-Argáez Marco , Jardón Enrique , González-Rivera Carlos
Published: October 2015

In this study a process analysis of the melting process of solid particles in a bath of same composition is performed using both experimental information and theoretical computations. An experimental setup was used to measure the thermal histories and to follow the evolution with time of the size of solid metallic spherical particles being melted in a metallic bath of same composition. For such a purpose, pure aluminum was used during the experiments for both solid particles and liquid bath. A mathematical model was also developed based on first principles of heat transfer to simulate the melting kinetics of a cold metallic spherical particle immersed in a hot liquid bath of same composition. The mathematical model was reasonably validated when compared against the experimental results obtained in this work. A process analysis of the melting process was performed to determine the effect of the initial temperature and size of the solid particle, the bath temperature and the convective heat transfer coefficient on the melting time and on the energy consumption.

The analysis showed that the variable presenting the most significant effect on both the melting time and the energy consumption is the convective heat transfer coefficient between the particle and the bath, since an increment in such a parameter accelerates the melting process and saves energy. Therefore, proper stirring of the bath is highly recommended to enhance the melting of metallic alloying additions in the metallic baths.
Recent Interpretations of the Laws of Zakat with Regard to People with Disabilities
Authors: Rispler-Chaim Vardit
Published: October 2015

Zakat is considered the earliest social solidarity system that does not depend on voluntary charity but on orderly periodic government support. In this article I trace interpretations of the zakat laws on people with disabilities in the past and the present in respect of two main questions: is a disabled person subject to zakat taxation? and does a disabled person qualify as a beneficiary of funds collected through the zakat taxation? The main conclusions are that if and when the economic situation of people with disabilities is similar to that of the healthy, they are subject to taxation. People with disabilities become beneficiaries of zakat funds only when they are “poor,” “needy,” and unable to support themselves, but never only because of the disability.
Ibn 'Ata' Allah al-Sakandari
Authors: Abdelaziz Mohamed Mohamed Mosaad
Published: October 2015

Ibn 'Ata' Allah al-Sakandari (d 1309) is known as the true founder of the Šadhili Madhhab. Little is known about his role in creating both social peace and political stability in Mamluk Egypt. Comparing him to Ibrahim al-Dusuqi , I will study three aspects of this role. First, I will study his introduction of a new model of the Sufi-the Faqih vis-à-vis the Sufi-the Theologian, a model that created reconciliation between the two historical enemies: the Sufis and the Jurists. Second, Ibn 'Ata' Allah moved from Alexandria to Cairo to be a teacher at al-Azhar University, turning Sufism into a respected discipline, and closing the gap between urban Islam and periphery Islam. Third, he forged a political alliance with Sultan Qalawun that saved the Sultan enough popular support to create political stability after long years of political turmoil.
TABARAN: INTERCULTURAL EXCHANGE, PARTICIPATION AND COLLABORATION
Authors: Webb Michael
Published: October 2015

Musical appropriation is a two-way traffic and elements from new musical vocabularies are assimilated by various parties for different ends. In this article I address issues involved in musical border crossing (and border repositioning) in the context of examining Tabaran, the musical collaboration between musicians of Rabaul, Papua New Guinea and the Melbourne musicians, Not Drowning, Waving (henceforth NDW), released early in 1991
Blurring of collective identities in the post-Soviet space
Authors: Ehala Martin
Published: October 2015

The paper focuses on collective identity formation in the post-Soviet space, applying the Sign Theory of Identity, which claims that collective identity is a type of Social Sign, which structure the social world and legitimise the distribution of power and resources. The paper specifies the functional and structural differences between ethnic, ethnic national, civic national, imperial and linguistic identities; outlines the conditions for identity blurring, using the notions of identity density and identity distance; characterises the main paths of identity blurring; and presents an analysis of the collective identity dynamics in the post-Soviet space, based on the case studies in this special issue.
DIFICULDADES DO PROCESSO DE ORIENTAÇÃO EM TRABALHOS DE CONCLUSÃO DE CURSO (TCC): UM ESTUDO COM OS DOCENTES DO CURSO DE ADMINISTRAÇÃO DE UMA INSTITUIÇÃO PRIVADA DE ENSINO SUPERIOR
Authors: Medeiros Bruno Campelo , Silva Ruthilene Catarina Lima da , Rocha Fabrícia Abrantes Figueiredo da , Danjour Miler Franco
Published: October 2015

O artigo aborda as dificuldades encontradas por professores durante o processo de orientação de trabalhos de conclusão de curso (TCC´s) de alunos do curso de Administração. Foi desenvolvido um estudo de campo, com dados coletados junto a um universo de 30 docentes do curso de uma instituição privada de ensino superior através de um questionário que contemplou além da análise do perfil do docente, três aspectos fundamentais para a realização deste tipo de trabalho, que são: o conhecimento em metodologia (aspecto cognitivo), o planejamento de pesquisa (aspecto operacional) e a forma de orientação (aspecto da relação professor-aluno). Os resultados apontam as principais dificuldades inseridas no processo de orientação, que vão desde características dos docentes bem como à forma e o envolvimento dos discentes durante a construção de trabalho. Os resultados, apesar de limitados por uma pequena amostragem, podem servir de suporte de informação para o processo de planejamento das ações de formação por professores e coordenadores de curso.
ANÁLISE DE UMA ORGANIZAÇÃO FAMILIAR À LUZ DO MODELO MULTIDIMENSIONAL-REFLEXIVO
Authors: Ferraz Isabela Neves , Cavalcanti Junior Henrique Sérgio Barros , Ferraz Maíra Neves
Published: October 2015

O principal objetivo deste trabalho consiste em analisar, a partir da realização de um estudo de caso, uma organização familiar, tendo como referência o Modelo Multidimensional-Reflexivo de Alves (2003). Todos os característicos retratados no presente artigo, obtidos através da pesquisa documental, entrevistas e observação não-participante, e analisados por meio da técnica de análise de conteúdo, permitiram, como principal achado, o enquadramento da empresa familiar analisada como uma organização, de fato, equiparativo-adaptadora, à luz do modelo formulado por Alves (2003).
A EDUCAÇÃO EM SAÚDE AMBIENTAL NOS SERVIÇOS DE SAÚDE DO SUS
Authors: Alves Maria Lima , Ximenes Maria de Fátima Feire Melo , Araújo Magnólia Florêncio Fernandes
Published: October 2015

A necessidade de transcender os limites da sala de aula mediante o exercício de atividades educacionais desenvolvidas em ambientes diversos deve ser pautada considerando-se as particularidades e necessidades que configuram cada ambiente. Assim sendo, a implementação de ações educativas na perspectiva da saúde ambiental nas instituições de saúde são necessárias diante da crescente demanda que envolve questões ambientais nestes serviços. O objetivo do estudo consistiu em difundir os princípios da educação em saúde ambiental em estabelecimentos de saúde do SUS no município de Mossoró-RN. Elencou-se como público alvo profissionais da área e como estratégia pedagógica a metodologia da pesquisa-ação. Diferentes fases metodológicas foram percorridas possibilitando a interação entre os sujeitos da pesquisa e a pesquisadora. As discussões envolvendo a temática da educação em saúde ambiental favoreceram a construção de debates reflexivos acerca das responsabilidades individuais e coletivas que refletem nas questões ambientais em saúde e, sobretudo da necessidade de mudanças de comportamentos e atitudes que promovam a saúde coletiva e a qualidade do ambiente nos serviços de saúde do SUS.
DESAFIOS EMERGENTES NA AÇÃO EDUCATIVO-AMBIENTAL: UMA EXPERIÊNCIA EM CENTROS DE EDUCAÇÃO INFANTIL DE CURITIBA – PR
Authors: Campos Marília Andrade Torales , Carvalho Andrea Macedônio de
Published: October 2015

A inserção da Educação Ambiental nos cenários educativo-institucionais aponta para a criação de alternativas necessárias frente às evidências de uma crise ambiental. Com esta perspectiva, a análise da práxis dos docentes é importante para avaliar as propostas educativas desenvolvidas em Centros de Educação Infantil, tomando como referência o ponto de vista e a ação dos professores. O objetivo deste trabalho foi a elaboração de um conjunto de estratégias de intervenção estimuladoras de um diálogo efetivo entre as acadêmicas do curso de Pedagogia e a realidade profissional que as professoras vivenciam em um Centro Municipal de Educação Infantil (CMEI) de Curitiba, através da análise de práticas e discursos das docentes no que se refere à temática educativo-ambiental. A compreensão da proposta pedagógica da escola foi o ponto de partida para estruturar nossa proposta de intervenção e o estabelecimento de diálogo com as profissionais que atuam no CMEI. Através de entrevistas e aplicação de questionários a dez professoras, foi possível identificar as características das prática de Educação Ambiental elaboradas pelas professoras e educadoras. As professoras se manifestaram positivamente sobre a necessidade de que iniciativas como essa sejam repetidas nos próximos anos e que o número de CMEIs participantes fosse ampliado. Acredita-se que os resultados obtidos por meio desta pesquisa possam contribuir para repensar o processo de inserção da Educação Ambiental no contexto educativo institucional e para a elaboração de políticas públicas coerentes com as necessidades manifestadas pelas profissionais que participaram do projeto.
VALIDAÇÃO ESTOCÁSTICA DE UM RECEPTOR RFID COM MÚLTIPLO ACESSO POR DIVISÃO DE CÓDIGO E PROCESSAMENTO POR DECOMPOSIÇÃO DE FATORES PARALELOS.
Authors: Braga Teixeira Francisco Hitalo James , De Aquino Francisco José Alves , Barros Tavares Daniel Alencar
Published: October 2015

A aplicação de sistemas RFID (Identificação por Rádio Frequência) é uma importante ferramenta para o desenvolvimento e segurança dos processos industriais e afins. No entanto, o uso desta tecnologia em cenários com densas populações de transponders ainda não é trivial e muito menos comum em nosso cotidiano. O processo de singularização em ambientes com múltiplo acesso requer um sistema de controle eficiente e capaz de reduzir interferências, executando a distinção entre os vários sinais transmitidos no canal compartilhado.   Neste trabalho, propomos ser válido o conceito de unicidade para um receptor RFID modelado com CDMA (Múltiplo Acesso por Divisão de Código) e o Algoritmo PARAFAC (Decomposição por Fatores Paralelos). Portanto a arquitetura consiste num tratamento de dados multilinear capaz de identificar e processar, simultaneamente, múltiplos transponders RFID a partir de um canal de rádio frequência compartilhado. O artigo apresenta uma introdução sobre os conceitos inerentes à pesquisa, bem como um conjunto de simulações para validar o modelo.
O SOFRIMENTO E A DOR COMO CONSTITUINTES DA BELEZA ESPORTIVA: REFLEXÕES PARA A EDUCAÇÃO
Authors: Cavalcanti Loreta Melo Bezerra , Porpino Karenine Oliveira
Published: October 2015

Pretende-se investigar as relações entre beleza, sofrimento e dor na Ginástica Rítmica (GR). Compreende-se que as construções de beleza, sofrimento e dor entremeiam-se numa complexa trama de sentidos: o corpo, fazendo com que ginasta e coreografia se constituam como uma obra de arte minuciosamente lapidada. Esta investigação possui como questão de estudo: Que referenciais para pensar a educação, inerentes à formulação da beleza na GR, emergem enquanto reflexões a partir do sofrimento e da dor? Deseja-se, a partir da abordagem fenomenológica, refletir sobre a preparação de ginastas da Ginástica Rítmica para competições esportivas buscando observar, descrever e compreender a constituição da beleza na GR, enquanto esporte de natureza artística, considerando o sofrimento e a dor como elementos que a permeiam, mas que também se reverberam numa dimensão existencial e trazem referenciais para Educação. Para tanto, o presente artigo encontra-se no formato de ensaio teórico organizado a partir de dois eixos de reflexão: Sofrimento e dor que produzem beleza e Reflexões para a educação.
ANÁLISE DE UM TIME DE TRABALHO À LUZ DO FRAMEWORK SCRUM: O CASO DE UMA ORGANIZAÇÃO PÚBLICA FEDERAL DE EDUCAÇÃO PROFISSIONAL E TECNOLÓGICA
Authors: Rosa Gustavo Danicki Aureliano , Massukado Luciana Miyoko , Stumpf Elisabeth Regina Tempel
Published: October 2015

O desenvolvimento de produtos exige controles e processos organizacionais eficientes para a sinergia de competências entre diferentes indivíduos de uma equipe. Partindo-se deste pressuposto, e levando-se em conta que o framework SCRUM foi desenvolvido para integrar equipes em torno do desenvolvimento de produtos complexos, o objetivo deste artigo foi analisar a dinâmica de uma equipe de trabalho de uma organização pública federal de educação profissional e tecnológica à luz do SCRUM. A pesquisa possuiu natureza quantitativa e foi realizada com cinco indivíduos, sendo que os dados sobre suas percepções foram coletados por meio de levantamento survey com itens estruturados na forma da escala Likert. Os resultados da pesquisa forneceram um diagnóstico do time de trabalho pesquisado e seu ambiente atual, sendo identificados pontos convergentes (multifuncionalidade na equipe, existência de espaço para adaptação, desenvolvimento transparente dos produtos e frequência de entregas de produtos funcionais) e pontos divergentes com princípios do SCRUM (cultura de inspeção, autogerenciamento da equipe, e realização de planejamentos contínuos). A aderência das respostas aos requisitos baseados no framework SCRUM, evidenciando os pontos fortes e fracos da equipe, poderá embasar o gestor na tomada de decisões com vistas à melhoria do gerenciamento das atividades desenvolvidas pela unidade analisada.
FORMAÇÃO INICIAL DE PROFESSORES DE BIOLOGIA NO IFRN: A CONCEPÇÃO DOS LICENCIANDOS SOBRE O ENSINO/ENSINAR
Authors: Morais João Kaio Cavalcante de , Albino Giovana Gomes
Published: October 2015

A formação inicial de professores é uma das temáticas mais recorrentes no cenário educacional brasileiro nas últimas décadas, tendo em vista a problemática envolvendo o ensino nas escolas do país. Em meio a esse contexto, a presente pesquisa decorre das inquietações dos autores em entender as concepções que os graduandos do curso de licenciatura plena em Biologia do IFRN campus Macau apresentam sobre o ensino. Para tanto, evidencia como objetivo analisar essas concepções de ensino ressaltadas pelos sessenta e três (63) alunos participantes. Como critério para a interpretação dos dados foi utilizada a técnica de análise de conteúdos (BARDIN, 2011), além do amparo teórico centrado na formação docente que enfatiza o caráter qualitativo da pesquisa. Os resultados mostram que os sujeitos evidenciam duas (2) concepções sobre o ensino:  a primeira pautada na perspectiva tradicional, mais amplamente presente nos discursos; e a segunda centrada na ideia de construção do conhecimento, aproximando-se das abordagens mais progressistas. Em vista de tal cenário, os resultados impulsionam a necessidade de que novos contornos possam ser dispensados à referida formação no curso enfatizado, a fim de que a realidade alcance perspectivas ainda mais amplas sobre o significado da ação de ensinar, do papel do docente nesse fazer e, principalmente, do sentido atribuído ao aluno mediante os processos de ensino e de aprendizagem a que o mesmo se vincula.
PERFIL DE HOMENS NA ATENÇÃO PRIMÁRIA À SAÚDE
Authors: Santiago Fabiana Pinheiro , Souza Poliana R. Filgueira de , Machado Flávia C. de Azevedo , Fernandes Eliana Regina Lima
Published: October 2015

Características próprias do universo masculino como o simbolismo da masculinidade podem dificultar práticas de autocuidado, bem como a procura por serviços de saúde, tornando este grupo mais vulnerável ao adoecimento. Com intuito de reverter este panorama, criou-se no Brasil a Política Nacional de Atenção Integral a Saúde do Homem (PNAISH). Assim, este estudo busca traçar o perfil de homens que acessaram serviços da atenção primária da Zona Norte de Natal/RN e verificar o conhecimento da PNAISH por este grupo. Para tanto, realizou-se um estudo seccional com 155 homens entre 20 e 59 anos que responderam a um questionário para caracterizá-los quanto: condição socioeconômica, hábitos, perfil de doença, conhecimento da PNAISH e percepção quanto ao serviço de saúde acessado. Assim foi constatado, dentre outros aspectos, que a maioria dos indivíduos eram pardos, tinham baixa escolaridade, renda entre 1 e 2 salários e desconheciam a PNAISH. Em relação ao serviço, 90,3% disseram ter resolvido sua demanda, porém apenas 55,4% consideraram a assistência satisfatória. Por conseguinte, homens que acessam a atenção primária são, em sua maioria, de baixa condição socioeconômica e desconhecedores da PNAISH. Assim, é necessário disseminar mais informações sobre esta política e adequar os serviços de saúde para atender as reais necessidades da população masculina.
CONCEPÇÕES DE FORMAÇÃO PROFISSIONAL TÉCNICA DE NÍVEL MÉDIO ADOTADAS PELO IFRN: ESPECIFICIDADES E (DES)CONTINUIDADES
Authors: Silva Jose Moises , Cabral Neto Antonio
Published: October 2015

O artigo trata das concepções de formação profissional técnica de nível médio adotadas pelo IFRN. Discute essas concepções a partir dos quatro Projetos Político-Pedagógicos (PPPs) construídos no período de 1970 a 2010, abrangendo três institucionalidades: ETFRN (1970-1998), CEFET-RN (1999-2008) e IFRN (a partir de 2009). O objetivo é analisar como se configuram as concepções de formação profissional adotadas nos PPPs, com ênfase nas especificidades e (des)continuidades entre os referidos projetos. Como orientação teórico-metodológica adotou-se a dialética e como procedimento de pesquisa a revisão bibliográfica, a pesquisa documental e as entrevistas com sujeitos que participaram do grupo de trabalho que coordenou a elaboração dos PPPs. Os resultados evidenciam que entre os PPPs, dos períodos analisados, há mais continuidades do que rupturas em relação às concepções de formação profissional adotadas. Conclui-se que, embora a utopia do IFRN, no momento atual, seja consolidar, em suas ações educativas, a concepção de formação humana integral, na prática, essa é apenas uma possibilidade em construção.
Metabolitos aislados de raputia heptaphylla y esenbeckia alata (rutaceae) y síntesis de precursores de análogos de alcaloides quinolínicos
Authors: Coy Barrera Carlos A. , Cuca Suárez Luis E.
Published: October 2015

Abstract. Previous studies on the Esenbeckia alata and Raputia heptaphylla,

both species belonging to the Rutaceae family, have shown

important results with respect to their chemistry. These species have

secondary metabolites (coumarins and alkaloids mainly), which act as

chemotaxonomic markers. This paper presents, for the first time, the phytochemical

work and isolated metabolites in these species: four coumarins:

bergapten, xanthyletin, xanthotoxin, 3-isoprenyl-4-methoxy-coumarin;

four alkaloids: skinmianine, kokusaginine, dictamnine, and 1-methyl-2-

methoxy-4-quinolone; two lignans: sesamin and mesodihydroguaiaretic

acid; two sterols: -sitosterol, stigmasterol; and a pentacyclic triterpene:

lupeol that have been isolated from leaves of E. alata. Five alkaloids

7-methoxy-2,2-dimethyl-2,6-dihidro-piran[3,2,c] quinolin-5-one, flindersiamine,

skinmianine, kokusaginine and dictamnine that have been isolated

from leaves of R. heptaphylla. Moreover, it presents a new method by

obtaining quinolone alkaloid analogue precursors trough the condensations

of Mannich adduct vinylogous and aldehydes followed by radical

cyclization to obtain products with high regio- and stereoselectivity.

 
Análisis de la distribución del tamaño de partícula de agregados de porfirinas por dispersión dinámica de luz
Authors: Díaz Uribe Carlos E. , Vallejo William
Published: October 2015

La formación de sus agregados recibe considerable interés

debido a las distintas aplicaciones ópticas y electrónicas. La distribución

del tamaño de partícula es una propiedad fundamental para caracterizar

sistemas de partículas en suspensión de agregados moleculares. En este

trabajo se estudió la distribución del tamaño de partícula de agregados de

tetracarboxifenilporfirinas de Zn (TCPPZn) y Cu (TCPPCu) en solución.

Los compuestos fueron sintetizadas utilizando la metodología desarrollada

por Achar. Las tetracarboxifenilporfirinas fueron caracterizadas por

espectrofotometría y el tamaño de partícula en solución fue determinado

por Espectroscopia de Correlación Fotónica (ECF). Los resultados de

espectro fotometría mostraron las señales características de tetracarboxifenilporfirinas;

adicionalmente el estudio del tamaño de agregados mostró

un valor promedio de 5419 nm para los agregados de TCPPZn, mientras

que para la TCPPCu fue de 5560 nm.
El problema de Cauchy asociado a la ecuación no lineal de Schrödinger forzada paramétricamente
Authors: Martínez Rojas Luisa Fernanda
Published: October 2015

El propósito de este trabajo es abordar el buen planteamiento en los espacios de Sobolev H1(R),H2(R) del problema de Cauchy, asociado a la ecuación lineal de Schrödinger, forzada paramétricamente para modelar fenémenos físicos que se presentan en óptica.
Producción de hidrógeno a partir de energía solar. Panorama en Colombia
Authors: Lache Muñoz Andrea
Published: October 2015

La generación de energía a partir de fuentes renovables como el sol, representa una oportunidad para reducir la emisión de gases de efecto invernadero, los cuales han sido los responsables de la aceleración del cambio climático, en los últimos años. A su vez, el hidrógeno es considerado el vector o gestor energético ideal para las energías de tipo renovables, que puede facilitar la implementación de un nuevo modelo de suministro energético, para países como Colombia, que en un mediano y largo plazo, la energía solar ampliamente disponible, promueva la independencia energética, garantice el suministro en todo el territorio y aporte tanto bienestar ambiental como social en materia energética.
Desarrollo de competencias integrales con tecnologías de la información y de la comunicación en educación superior a distancia
Authors: Muñoz Vargas Isabel Cristina , Rodríguez Pichardo Catalina María , Monroy Íñiguez Felipe Jesús
Published: October 2015

El estudio buscó identificar e implementar estrategias didácticas con uso de tecnologías de la información y de la comunicación (TIC), que favorecieran el desarrollo de competencias integrales en los estudiantes de educación a distancia de la Licenciatura en Ciencias Naturales y Educación Ambiental de la Universidad de Córdoba. Se utilizó el método de investigación acción, en dos ciclos, donde participaron tres docentes y 242 estudiantes. El análisis de datos en el primer ciclo estableció tres categorías de análisis y el diseño de cuatro estrategias de intervención basándose en el conocimiento científico y la experiencia académica de los docentes. En el segundo ciclo, los resultados muestran que los alumnos mejoraron académicamente de manera integral.
Las tecnologías de la información y de la comunicación en el currículo de matemáticas: orientación desde las políticas y los proyectos educativos
Authors: Arévalo Duarte Mayra Alejandra , Gamboa Suárez Audin Aloiso
Published: October 2015

Este artículo analizó los criterios que orientan la integración de las tecnologías de la información y de la comunicación en el currículo de matemáticas desde las políticas y los proyectos educativos desarrollados en Colombia. El estudio se abordó desde el enfoque cualitativo utilizando el análisis de contenido vertical como método de investigación. Los resultados del proceso de análisis de configuran algunos aspectos para orientar la integración de las tecnologías de la información y de la comunicación en el currículo de matemáticas. Se concluyó que las políticas y proyectos desarrollados en torno a las tecnologías de la información y de la comunicación son un insumo fundamental para construir las bases teóricas y metodológicas de la incorporación de estas en el sistema educativo y para caracterizar el contexto que le permitirá a las instituciones educativas comprender las exigencias del Estado y la sociedad para plantear currículos pertinentes y viables según las metas y propósitos de la educación en Colombia.
Desarrollo de los niveles de razonamiento geométrico según el modelo de Van Hiele y su relación con los estilos de aprendizaje
Authors: Fuentes Hernández Nevis María , Portillo Wilches Jorge Camilo , Robles Juana Raquel
Published: October 2015

El objetivo de artículo fue evaluar la eficacia del modelo de Van Hiele en el avance en los niveles de razonamiento geométrico de los estudiantes de grado 7º de una institución educativa oficial en Córdoba (Colombia) y su relación con los estilos de aprendizaje. El estudio se abordó desde un enfoque cuantitativo de tipo cuasiexperimental, incluyó un test para identificar el nivel de razonamiento geométrico de los estudiantes antes y después de la intervención, la aplicación de una secuencia didáctica acerca de polígonos teniendo en cuenta las fases de aprendizaje según del modelo de Van Hiele, además de un test para identificar estilos de aprendizaje. Para el análisis de resultados se aplicaron las pruebas no paramétrica de Wilcoxon, de Mann-Whitney y chi-cuadrado, disponibles en el software SPSS 17. Se destaca que los estudiantes lograron mejoras significativas en cuanto a los grados adquisición de los niveles 1 y 2 de Van Hiele, luego de la intervención con la secuencia didáctica. Además se encontró, como en estudios anteriores, que el estilo predominante en los grupos fue el reflexivo, sin embargo no se encontraron diferencias significativas entre los estilos de aprendizaje y la mejora en los niveles de razonamiento, con lo cual se concluye que el modelo fue eficaz para la mayoría de los estudiantes independientemente de su estilo de aprendizaje.
Estructura y sujeto del inconsciente: la ficción de lo simbólico
Authors: Peña Pinzón Evaristo
Published: October 2015

Hablar de epistemología en psicoanálisis implica un doble trabajo: el de encontrar los vestigios en la teoría analítica, preferentemente en los aportes de Freud y Lacan, y el de revisar fuera del contexto de la disciplina los conceptos con que se alimenta. En muchas ocasiones, estos conceptos provienen de diferentes orillas del conocimiento, lo cual implica un esfuerzo adicional de dar su lugar a cada una de las nociones, específicamente para notificar lo que sucede en esos dos espacios cruciales para el psicoanalista, la clínica y la cotidianidad. En este orden de ideas, este trabajo trae a colación dos conceptos muy importantes para las actividades comprometidas con la clínica y la cotidianidad: las nociones de estructura y sujeto en psicoanálisis, así como su relación y alcance.
The Association Between PD-L1 Expression and the Clinical Outcomes to Vascular Endothelial Growth Factor-Targeted Therapy in Patients With Metastatic Clear Cell Renal Cell Carcinoma
Authors: Shin Su-Jin , Jeon Yoon Kyung , Cho Yong Mee , Lee Jae-Lyun , Chung Doo Hyun , Park Ji Young , Go Heounjeong
Published: October 2015

Background.

Vascular endothelial growth factor pathway (VEGF)-tyrosine kinase inhibitors (TKIs) are used as the first-line treatment for patients with metastatic clear cell renal cell carcinoma (mCCRCC). Recently, programmed death-1 (PD-1) and programmed death ligand-1 (PD-L1) blockade emerged as promising therapy for renal cell carcinoma. However, the expression pattern and prognostic implication of programmed death-ligands (PD-Ls) in mCCRCC patients receiving VEGF-TKI remain unclear.

Patients and Methods.

PD-L1 and PD-L2 expression in tumor cells and the quantities of PD-1+ tumor-infiltrating lymphocytes were immunohistochemically evaluated in 91 mCCRCC patients treated with VEGF-TKI, and their associations with VEGF-TKI responsiveness and clinical outcome were analyzed.

Results.

PD-L1 immunopositivity was observed in 17.6% and significantly associated with a high International Society of Urological Pathology grade (p = .031) and sarcomatoid features (p = .014). PD-L2 immunopositivity was observed in 39.6% and was not associated with any of the assessed clinicopathological variables. PD-L1-positive cases showed poor VEGF-TKI responsiveness (p = .012) compared with PD-L1-negative cases. In univariate survival analysis, PD-L1 immunopositivity was significantly associated with shorter overall survival (OS) (p = .037) and progression-free survival (PFS) (p = .043). Multivariate survival analysis revealed that PD-L1 expression was independently associated with poor OS (p = .038) and PFS (p = .013) in addition to tumor necrosis (p = .006; p = .029, respectively) and Memorial Sloan Kettering Cancer Center score (p = .018; p = .032, respectively). PD-L2 expression was neither associated with VEGF-TKI responsiveness nor patients’ outcome.

Conclusion.

PD-L1 expression was significantly related to lack of VEGF-TKI responsiveness and independently associated with shorter survival in mCCRCC patients after VEGF-TKI treatment. PD-L1 may have a predictive and prognostic value for determining the value of VEGF-TKI treatment in patients with mCCRCC.

Implications for Practice:

Vascular endothelial growth factor pathway (VEGF)-tyrosine kinase inhibitors (TKIs) are essential for the treatment of metastatic renal cell carcinoma patients, but the treatment suffers from a lack of predictive markers. This study demonstrates that PD-L1 expression is a predictor for unfavorable response to VEGF-TKI and a prognostic indicator for poor overall survival and progression-free survival in patients with metastatic clear cell renal cell carcinoma receiving VEGF-TKI.
Phase II Trial of Nilotinib in Patients With Metastatic Malignant Melanoma Harboring KIT Gene Aberration: A Multicenter Trial of Korean Cancer Study Group (UN10-06)
Authors: Lee Su Jin , Kim Tae Min , Kim Yu Jung , Jang Kee-Taek , Lee Hyo Jin , Lee Soon Nam , Ahn Mi Sun , Hwang In Gyu , Lee Suee , Lee Moon-Hee , Lee Jeeyun
Published: October 2015

Background.

KIT has been suggested to be a potential therapeutic target for malignant melanoma. We evaluated the antitumor activity and safety of the KIT inhibitor nilotinib in metastatic melanoma patients harboring KIT gene mutations or amplifications.

Methods.

We conducted a phase II multicenter trial of nilotinib in metastatic malignant melanoma with KIT mutations or amplifications. Patients received 400 mg oral nilotinib twice daily. The primary endpoint was response rate, and if seven or more responders were observed from the cumulative 36 patients, nilotinib would be considered worthy of further testing in this study population.

Results.

Between October 2009 and June 2013, 176 patients underwent molecular screening for KIT gene aberrations, and 42 patients harboring KIT gene mutations and/or amplification were enrolled in the study. Overall, 25 (59.5%), 15 (35.7%), and 2 (4.8%) patients had KIT mutations, KIT amplifications, and both KIT mutations and amplification, respectively. Of the 42 enrolled patients, 1 patient achieved complete response, 6 patients achieved partial response, and 17 patients achieved stable disease, resulting in an overall response rate of 16.7% (95% confidence interval [CI]: 5.4%−28.0%) and a disease control rate of 57.1% (95% CI: 42.1%−72.1%). The median duration of response was 34 weeks (range: 5–55 weeks). Of the 7 responders, 6 patients had KIT mutations (exon 11: 5 patients; exon 17: 1 patient), and 1 patient had KIT amplification only.

Conclusion.

Although this study did not meet its primary endpoint of response rate, nilotinib showed durable response in a subset of metastatic melanoma patients with specific KIT mutations.

Implications for Practice:

KIT aberration can be detected in a subset of metastatic melanoma patients. This phase II trial showed that nilotinib demonstrates durable response in a subset of patients with KIT mutations. The safety profile was very tolerable. This study suggests that a KIT inhibitor may benefit a small subset of metastatic melanoma patients with KIT mutations.
Blog v1
Authors: homes john
Published: October 2015

Blog
Editorial
Authors: Delduque Maria Célia
Published: October 2015

Editorial
Literacies for Surveillance: Social Network Sites and Background Investigations
Authors: Jackson Young Sarah
Published: October 2015

In September 2013, civilian contractor Aaron Alexis entered the Washington Navy Yard and murdered twelve people before being fatally shot by police. This incident, together with an incident three months earlier involving Edward Snowden, caused the U.S. government to critically examine their background investigation (BI) process; because both Snowden and Alexis had supposedly slipped through the cracks of their investigations, there must be some flaw in the BI procedure. The U.S. Committee on Oversight and Reform concluded that rules forbidding “background checkers from looking at the Internet or social media when performing checks” was one of the main factors contributing to defective BIs (Report, 2014). Since the report’s release, the Director of National Intelligence has been debating and trialing whether information from the Internet should be used to form a data double for BIs (Kopp, 2014; Rockwell, 2014). Using this conversation as a discussion catalyst, I argue that due to the nature of the data double, if the United States were to adopt the use of social networking sites (SNSs) for security clearance purposes, neglecting to take into account basic principles of SNSs into the process of BIs may lead to misinformation and unfavorable adjudication. Ultimately, being literate about the social practices involved in SNSs and surveillance would benefit not only investigators, but anyone, including academics, looking at individuals in online spaces.