bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effect of Tax Socialization and Tax Rates to Restaurant Taxpayable Compliance in The City of Sukabumi
Authors: Permana Irsan , Susianto Triendar
Published: January 2021

This study aims to determine the tax socialization, tax rates, tax compliance, the influence of tax socialization on tax compliance, the influence of tax rates on tax compliance, and the effect of tax socialization and tax rates on restaurant taxpayer compliance in Sukabumi City.

The research method uses quantitative methods with descriptive-associative methods. The unit of analysis used is restaurants in Sukabumi City, with the population used are all restaurants in Sukabumi City, and the total sample size of 70 respondents. Data collection techniques in the form of a questionnaire containing 19 indicator statements and determined by the simple random sampling method. Analysis of the data used is the instrument test, classic assumption test, descriptive analysis, multiple correlation analysis, coefficient of determination analysis, multiple linear regression analysis, and t test (partial test) and F test (simultaneous test).

The results of this study indicate that; 1) tax socialization based on restaurant respondents' responses shows that on the whole the overall response was agreed with the tax socialization conducted towards restaurants in Sukabumi City. 2) tax rates based on respondents' responses indicate that on average the overall response was neutral with the imposition of tax rates on restaurants in the City of Sukabumi. 3) taxpayer compliance based on respondents' responses shows that on average the overall respondent agreed to the compliance of restaurant taxpayers in Sukabumi City, in the sense that respondents were compliant with the existence of taxpayers to their respective restaurants. 4) tax socialization has a positive and significant effect on restaurant taxpayer compliance in Sukabumi City. 5) tax rates have a positive and significant effect on restaurant taxpayer compliance in Sukabumi City. 6) tax socialization and tax rates have a positive and significant effect on restaurant taxpayer compliance in Sukabumi City.
O CONHECIMENTO LOCAL EM FACE DO ENEM: as implicações no ensino de Geografia do Piauí
Authors: Barbosa Aline Camilo , Silva Josélia Saraiva
Published: January 2021

Este trabalho apresenta os resultados de uma pesquisa que teve como objetivo identificar as concepções e as práticas dos professores relacionadas com a disciplina de Geografia do Piauí, o interesse da investigação se dá pelo fato de que após a implementação do Exame Nacional do Ensino Médio - ENEM, esta disciplina deixou de ser alvo de avaliação. A metodologia contou com a construção da fundamentação teórica e pesquisa de campo, realizada nas escolas públicas estaduais do município de Teresina-PI. Os dados mostram que os professores reconhecem a importância do ensino de Geografia do Piauí para viabilizar a compreensão dos alunos acerca da escala geográfica local, porém parte dos professores não busca alternativas para amenizar o impacto que o ENEM vem trazendo para essa disciplina no Ensino Médio. Assim, salientamos a necessidade de mudança de postura dos professores com relação ao ensino de Geografia do Piauí, para tanto sugerimos a oferta de formação continuada sobre essa temática com ênfase no uso diversificado de material didático. PALAVRAS-CHAVE Ensino de Geografia. Conteúdos. ENEM. Geografia do Piauí. CONOCIMENTO LOCAL EN CARA ENEM: las implicaciones para la enseñanza de la Geografia del Piauí RESUMEN Este trabajo presenta los resultados de un estudio que tuvo como objetivo identificar las concepciones y las prácticas de los maestros en la disciplina Geografía del Piauí, el interés de la investigación se da por el hecho de que después de la aplicación del Examen Nacional de Educación Secundaria – ENEM, esta disciplina ya no es objeto de evaluación. La metodología consistió en la construcción de un fundamento teórico y investigación de campo hecha en las escuelas públicas del estado en la ciudad de Teresina-PI. Los datos muestran que los profesores reconocen la importancia de la enseñanza de la Geografía del Piauí para facilitar la comprensión de los estudiantes acerca de la escala geográfica local, sin embargo los maestros no buscan alternativas para mitigar el impacto que el ENEM está trayendo a esta disciplina en la escuela secundaria . Por lo tanto, hacemos hincapié en la necesidad de un cambio de actitud de los maestros con respecto a la enseñanza de la Geografía del Piauí, por lo tanto, se aconseja la provisión de educación continua sobre este tema, centrándose en el uso diversificado de materiales de enseñanza. PALABRAS CLAVE Enseñanza de la Geografía. Contenido. ENEM. Geografia do Piauí. ISSN: 2236-3904REVISTA BRASILEIRA DE EDUCAÇÃO EM GEOGRAFIA - RBEGwww.revistaedugeo.com.br - revistaedugeo@revistaedugeo.com.br
Comparison of Reusable Models in Pericardiocentesis Simulation Training
Authors: Lin Ziwei , Soh Crystal Harn Wei , Chua Mui Teng , Lin Jingping , Ho Cheryl Jing Yi , Lee Julia Ying Hui , Shen Fang Yu Tracy , Yau Ying Wei , Kuan Win Sen
Published: January 2021

Abstract Introduction: Pericardiocentesis is a potentially life-saving procedure. We compared two low-cost models—an agar-based model and a novel model, Centesys—in terms of ultrasound image quality and realism, effectiveness of the model, and learners’ confidence and satisfaction after training. Methods: In this pilot randomised 2x2 crossover trial stratified by physician seniority, participants were assigned to undergo pericardiocentesis training either with the agar-based or Centesys model first, followed by the other model. Participants were asked to rate their confidence in performing ultrasound-guided pericardiocentesis, clarity and realism of cardiac structures on ultrasound imaging, and satisfaction on a 7-point Likert scale before and after training with each model. Results: Twenty participants with median postgraduate year of 4 (interquartile range [IQR] 3.75–6) years were recruited. Pre-training, participants rated themselves a median score of 2.5 (IQR 2–4) for level of confidence in performing pericardiocentesis, which improved to 5 (IQR 4–6) post-training with Centesys (P=0.007). Centesys was recognised to be more realistic in simulating cardiac anatomy on ultrasound (median 5 [IQR 4–5] versus 3.5 [IQR 3–4], P=0.002) than the agar-based model. There was greater satisfaction with Centesys (median 5 [IQR 5–6] versus 4 [IQR 3.75–4], P<0.001). All 20 participants achieved successful insertion of a pericardial drain into the simulated pericardial sac with Centesys. Conclusion: Centesys achieved greater learner satisfaction as compared to the agar-based model, and was an effective tool for teaching ultrasound-guided pericardiocentesis and drain insertion. Keywords: Cardiac tamponade, emergency medicine, medical education, pericardial effusion, ultrasonography
Association of Cord Blood Thyroid-Stimulating Hormone Levels with Maternal, Delivery and Infant Factors
Authors: Tan Karen ML , Chu Anne HY , Loy See Ling , Rajadurai Victor Samuel , Ho Clement KM , Chong Yap Seng , Karnani Neerja , Lee Yung Seng , Yap Fabian Kok Peng , Chan Shiao-yng
Published: January 2021

Abstract
Introduction: This study examined maternal, delivery and infant factors associated with
cord thyroid-stimulating hormone (TSH) concentrations in an Asian population.
Methods: The Growing Up in Singapore Towards healthy Outcomes (GUSTO) study is
a mother–offspring birth cohort from 2 major hospitals in Singapore. Cord serum TSH
was measured using the Abbott ARCHITECT TSH Chemiluminescent Microparticle
Immunoassay and the ADVIA Centaur TSH-3 Immunoassay. After excluding infants with
a maternal history of thyroid disease, screening cord TSH results from 604 infants were
available for multivariable regression analysis in relation to the factors of interest.
Results: Babies born by vaginal delivery had significantly higher cord serum TSH
concentrations than babies born by caesarean section. Cord serum TSH concentrations
differed significantly by measurement method. There was no association of cord TSH
concentrations with ethnicity, sex, birth weight, gestational age, maternal body mass index,
gestational weight gain, gestational diabetes mellitus status and other maternal, delivery
and infant factors studied.
Conclusion: Interpretation of cord serum TSH results may need to take into account mode
of delivery and measurement method.

Keywords: Cord blood, Growing Up in Singapore Towards healthy Outcomes,
GUSTO, perinatal
Nồng độ 25-hydroxy vitamin D huyết tương và các yếu tố nguy cơ của hội chứng chuyển hóa
Authors: Nguyễn Trọng Nghĩa , Nguyễn Thị Nhạn , Đào Thị Dừa , Trần Hữu An , Phạm Trung Hiếu
Published: January 2021

Đặt vấn đề: Hội chứng chuyển hóa (HCCH) là một tập hợp của các yếu tố nguy cơ chuyển hóa tim, có khuynh hướng nhóm lại với nhau ở các đối tượng bị ảnh hưởng  hơn là dự đoán một cách tình cờ. Sự hiện diện của HCCH làm tăng đáng kể nguy cơ xuất hiện đái tháo đường típ 2, bệnh tim mạch, từ đó liên quan chặt chẽ đến quá trình lão hóa và một loạt các kết cục xấu. Các nghiên cứu gần đây cho thấy thiếu vitamin D rất phổ biến trên thế giới và là một yếu tố nguy cơ của HCCH. Mục tiêu nghiên cứu: (1). Đặc điểm nồng độ 25-hydroxyvitamin D huyết tương ở đối tượng có HCCH. (2). Mối liên quan giữa nồng độ 25-hydroxyvitamin D huyết tương và các yếu tố nguy cơ của HCCH. Đối tượng và phương pháp nghiên cứu: Sử dụng phương pháp nghiên cứu mô tả cắt ngang có đối chứng ở 275 đối tượng người trưởng thành đến khám sức khỏe tại Trung tâm điều trị theo yêu cầu và quốc tế - Bệnh viện Trung ương Huế, trong đó nhóm bệnh gồm 94 đối tượng có HCCH và nhóm chứng gồm 181 người khỏe mạnh. HCCH được chẩn đoán theo đồng thuận của các tổ chức IDF, NHLBI, AHA, WHF, IAS, IASO năm 2009. Nồng độ 25-hydroxyvitamin D được đo bằng phương  pháp xét nghiệm miễn dịchvi hạt hóa phát quang. Kết quả: Nồng độ 25-hydroxyvitamin D huyết tương ở đối tượng có HCCH là 27,8 ng/mL, tỷ lệ giảm 25-hydroxyvitamin  D huyết tương là 87,2% cao hơn nhóm chứng là 24,9% có ý nghĩa thống kê (p<0,001). Có mối tương quan nghịch giữa nồng độ 25- hydroxyvitamin D huyết tương với vòng bụng, BMI, cholesterol toàn phần, triglycerid, giảm HDL-C, huyết áp tâm thu, huyết áp tâm trương và HbA1C (p<0,05 đến p<0,001). Kết luận: Nồng độ 25-hydroxyvitamin D huyết tương ở đối tượng có HCCH là 27,8  ng/mL, tỷ lệ giảm 25-hydroxyvitamin D huyết tương là 87,2%. Có mối tương quan nghịch giữa nồng độ 25-hydroxyvitamin D huyết tương với vòng bụng, BMI, cholesterol toàn phần, triglycerid, giảm HDL-C, huyết áp tâm thu, huyết áp tâm trương và HbA1C.
Khảo sát chức năng tuyến giáp ở phụ nữ vô sinh
Authors: Nguyễn Thị Phương , Vũ Bích Nga
Published: January 2021

Mục tiêu: Xác định tỷ lệ rối loạn chức năng tuyến giáp ở phụ nữ vô sinh và nhận xét một số yếu tố liên quan đến rối loạn chức năng tuyến giáp ở phụ nữ vô sinh. Phương pháp: Đối tượng nghiên cứu là 222 phụ nữ vô sinh (tuổi từ 18 – 45) được khảo sát làm xét nghiệm FT4, TSH. Yếu tố liên quan được khảo sát gồm: tuổi, BMI, tiền sử sản khoa xấu gồm thai lưu hoặc xảy thai, tình trạng kinh nguyệt, thời gian vô sinh, mức prolactin máu. Tình trạng rối loạn chức năng tuyến giáp được đánh giá dựa trên mức TSH trên hoặc dưới khoảng tham chiếu bình thường (TSH: 0,45 – 4,12) theo ATA 2012. Kết quả: Tỷ lệ rối loạn chức năng tuyến giáp trên nhóm bệnh nhân nghiên cứu là 12.7%. Tỷ lệ cường giáp là 3.2% gồm 0.5% cường giáp lâm sàng và 2.7% cường giáp dưới lâm sàng. Tỷ lệ suy giáp là 9.5% gồm 0.5% suy giáp lâm sàng và 9.0% suy giáp cận lâm sàng. Tỷ lệ rối loạn chức năng tuyến giáp tăng cao hơn ở nhóm phụ nữ lớn tuổi. Tỷ lệ rối loạn chức năng tuyến giáp ở nhóm trên 35 tuổi (chiếm 5.4%) cao hơn nhóm phụ nữ dưới 25 tuổi (1.4%).Tỷ lệ phụ nữ có tình trạng rối loạn kinh nguyệt là 32.7%, trong đó BN rối loạn chức năng tuyến giáp chiếm 4.6% và bệnh nhân bình giáp chiếm 28.1%. ở 4.6% bệnh nhân  rối loạn chức năng tuyến giáp giáp thì tỷ lệ rối loạn kinh nguyệt là 37% cao hơn nhóm bệnh nhân bình giáp ( 28.1%). Tỷ lệ tăng mức prolactin máu của nhóm nghiên cứu là 24.4% (bệnh nhân có rối loạn chức năng tuyến giáp chiếm 5.9% và bệnh nhân bình giáp chiếm 18.5%). ở những bệnh nhân có rối loạn chức năng tuyến giáp thì tỷ lệ tăng mức prlactin máu (46.4%) cao hơn nhóm bình giáp (21.1%). Tỷ lệ bệnh nhân có tiền sử sản khoa xấu bao gồm xảy thai, thai lưu trong nghiên cứu là 31.1%. (15.3% có tiền sử sảy thai, 9.9% có tiền sử thai lưu, 5.9% có cả tiền sử xảy thai và thai lưu). Kết luận: Tỷ lệ rối loạn chức năng tuyến giáp ở nhóm bệnh nhân nghiên cứu là 12.7%. Tỷ lệ rối loạn chức năng tuyến giáp tăng cao hơn ở nhóm tuổi trên 35. Tỷ lệ phụ nữ vô sinh có tình trạng rối loạn kinh nguyệt hoặc tăng mức prolactin máu ở nhóm rối loạn chức năng tuyến giáp thì cao hơn so với nhóm phụ nữ vô sinh bình giáp.
Béo phì và nhiễm COVID-19 nặng
Authors: Nguyễn Thị Nhạn
Published: January 2021

Béo phì có nguy cơ cao nhiễm COVID-19, với đặc trưng lâm sàng từ mức độ nhẹ đến tử vong. Hội chứng hô hấp cấp tính nặng do Coronavirus 2 (SARS-CoV-2) là do virus gây ra và có thể dẫn đến yêu cầu thở máy tại các đơn vị chăm sóc đặc biệt và tử vong sớm.Các tình trạng bệnh lý cần quan tâm ở bệnh nhânbéo phì như bệnh tim mạch, bệnh phổi, đái tháo đường, tăng huyết áp hoặc hội chứng ngưng thở khi ngủ do tắc nghẽn. Nếu không, sẽ có những đáp ứng miễn dịch không đầy đủ và quá mức, “cơn bão cytokine”, trầm trọng hơn bởi các kho chất béo “lạc cỗ” trong lồng ngực. Những phát hiện này đòi hỏi các biện pháp phòng ngừa và điều trị tăng cường ở những bệnh nhân béo phì bị nhiễm COVID-19, để hạn chế nguy cơ tiến triển thành dự hậu không tốt.
Snow mass characteristics for the indication of the ice-melting products application load
Authors: Voronina Lyudmila P. , Tribis Lev I. , Ponogaybo Ksenia E. , Amelyanchik Olga A. , Antropova Natalia S.
Published: January 2021

Introduction. For the time present, the active substances of many ice-melting agents used in Moscow are technical sodium and calcium chlorides. By degree of impact of sodium chloride on the human body is characterized as a moderately dangerous substance that belongs to the 3rd hazard class. Residents of megacities who remain unprotected from the possible harmful effects of these substances need the compliance of the ice-melting product’s application with appropriate security measures. Our research focused on the presence of these substances and their accompanying components in the transit environment and determining their actual and extreme loads to prevent possible functional changes in the future traffic chain objects. Material and methods. Chloride (Cl-) and sodium (Na+) content in the snow mass samples taken from the sites adjacent to motorways in Moscow were determined using ion chromatography. Other associated elements in the ice-melting agents were detected using inductively coupled plasma mass spectrometry method (ICP-MS). Results. According to the snow mass analysis as an object of transit accumulation and distribution of ice-melting reagents, the authors ranked results and identified clusters with different degrees of contamination for many indices. Selecting the group with very high contamination enabled us determine the indices’ levels that limit the use of deicing reagents. When using sodium-chloride reagents, they are the levels of the specific electrical conductivity (SEC) ≥ 4500 µS/cm, the concentration of chloride anions (Cl- ≥ 2500 mg/l), the concentration of sodium ions (Na+) ≥1500 mg/l, the index of total contamination (Zc).
The odours in the ambient air: analysis of the relationship with the state of health and quality of life in adults residing in the town with food industries
Authors: Goshin Mikhail E. , Budarina Olga V. , Ingel Faina I.
Published: January 2021

Introduction. The article is devoted to studying atmospheric air pollution by industrial odours on the health, quality of life, and the occurrence of various somatic and emotional disorders in the population of neighboring residential areas. According to most abroad studies, a literature review showed different conditions mediated by “annoyance” of smell, a “predictor” of deviations in health status. Material and methods. The data for this study were obtained as a result of the survey of residents of the city with a population of about 50 thousand residents living at different distances from odour sources: coffee factory, bone meal factory, a sugar factory, and solid waste landfill. The distances from the primary sources ranged from 1500 m to > 5 km. Results. The analysis showed that odour pollution is one of the priority factors affecting residents’ health and quality of life. The frequency and intensity of specific odours in the atmospheric air, according to the results of the survey, decrease as respondents’ place of residence is removed from sources (from 1500 m to > 5 km), as well as the degree of their “annoyance” with odours (from 87.5% to 51.2%), remaining at a very high level at the farthest distances (over 5 km). Conclusion. Besides to the area of residence and, accordingly, the level of atmospheric air pollution by odours, extent of this “annoyance” can be influenced by concern of residents about possible impact of air pollution, particularly by odours, on health. It has been established that there is a certain category of residents (making up about one-third of the population) who tend to associate their health problems with the state of the environment and, mainly, with the presence of industrial odours. This group of respondents is characterized by a lower tolerance to odours and, at the same time, a higher frequency of upper respiratory tract diseases, allergies, cardiovascular, and some other diseases.
Complexing ability of organic compounds and their influence on the human body (review)
Authors: Hlystov Ivan A. , Shtin Tat’yana N. , Gurvich Vladimir B. , Kuz´mina Elena A. , Bugayeva Aleksandra V. , Khar´kova Polina K.
Published: January 2021

Introduction. Increased content of organic substances in natural waters, expanding the list of input substances to water bodies, owing to industrial and economic activities of a person, and climate changes is an urgent issue. Against this background, compounds with unknown chemical and toxic properties are likely to appear. The purpose of this study is to collect data concerning the ways for organic compounds entering water bodies and the human body, study data on interaction mechanisms of organic substances with metals, reveal the fate of known organic chelators, complexing agents as well as organometallic compound shaped by them inside the body. The literature search was carried out in Scopus, Web of Science, CyberLeninka databases. Sources of organic substances entering water bodies, properties of organic substances. There are three types of organic substances in water bodies, divided by the sources of their occurrence (inflow): terrigenous origin, shaped inside water bodies and coming from man-made sources. Organic compounds may produce soluble and insoluble compounds with metals and colloids. Mechanisms of interaction of organic substances with metals. Bonding of organic substances takes place by the type of chelation and complexation. There are factors for bonding: functional group content, the molecular mass of substances, ion radius, and competitive interaction with binding sites. Substances having binding properties include phenolic compounds, carboxylic acids, polysaccharides, and flavonoids. Considering that phenolic compounds are located in large quantities in plant and animal tissues, this group of compounds has been researched more thoroughly in terms of interactions with metals and toxicometry. Intake of organic and organometallic compounds into the body, their kinetics, metabolism and decay. Organic compounds, chelates, and complexes enter the body with drinking water, food, and drugs. They are also generated in the body, including by replacing ions. Data on biochemical and toxicological studies of currently known compounds is given
The study of the odour impact on physiological, emotional, and cognitive aspects of human health under experimental conditions (literature review)
Authors: Ivanova Svetlana V. , Skovronskaya Svetlana A. , Goshin Mihail E. , Budarina Olga V. , Kulikova Aliya Z.
Published: January 2021

The article contains a literature review devoted to research on the influence of odours on physiological, emotional, and cognitive aspects of human health. The following databases were used at literature search execution: Pubmed, Scopus, Web of Science, MedLine, Global Health, Russian Research Citation Index. A total amount of 60 sources was analyzed for 1983-2019. The experimental research results aimed at studying the influence of odours on such physiological indices a: heart rate, heart rate variability, arterial blood pressure, respiratory rate, skin conductibility reaction, sleep, are described, and emotional and cognitive characteristics of the test subjects. The response to odours exposure was shown to depend on their intensity, hedonistic tone, the chemical structure of the odorant, as well as individual peculiarities of the test subjects, including their past experiences with smelling. In most cases, exposure to unpleasant odours activates the sympathetic nervous system, therefore heart rate, respiratory rate, skin blood circulation and its conductivity increase. Attention concentration increases at the deterioration of cognitive functions. Anger and repulsion reactions are noted at the emotional level; a feeling of discomfort with a motivation to escape appears. The exposure of pleasant odours leads to parasympathetic nervous system activation, heart rate, respiratory rate, skin conductibility, and blood circulation decrease. Cognitive functions improve, the quality of problem-solving increases, attention concentration decreases. A person’s mood gets better; the sensation of happiness appears. At that literature analysis has revealed most of the studies on the human to have significant restrictions: standard exposure methods absence, the difficulty of execution blind experiments that were deemed to be ignorant by test subjects as well as the influence of individual preferences and previous personal experience on the effects generated by the odour. The authors proposed recommendations on the current restrictions prevention and optimization of conducting the experimental research on the influence of odours on humans.
The impact of the weakly-fibrogenic bauxite dust on lungs in mine workers
Authors: Karpova Elena A. , Gazimova Venera G. , Gurvich Vladimir B. , Obukhova Tatyana Yu. , Gogoleva Olga I. , Plotko Eduard G. , Il´ina Marina I. , Ruzakov Vadim O.
Published: January 2021

Introduction. New cases of pneumoconiosis are detected annually at the bauxite mining enterprises of the Sverdlovsk Region. Differential diagnosis of bauxite pneumoconiosis with other interstitial lung diseases using only lung radiography can be difficult. The aim of the work was to clarify the nature of changes in the lungs of workers exposed to weakly fibrogenic dust of bauxite, and the relationship of changes in the lungs with working conditions in cases of difficulty in making the final diagnosis of pneumoconiosis. Material and methods. Underground miners of a working face and underground drifters with a work experience of at least ten years in conditions of exposure to bauxite dust were examined. All patients underwent a plain chest x-ray and high-resolution computed tomography (HRCT), bodyplethysmography, bronchoscopic examination with trans-bronchial biopsy, and subsequent histological examination of the biopsy. To determine the elemental composition of micro- and nanoparticles in biological tissue samples, scanning electron microscopy with X-ray spectral microanalysis was used. Results. During the histopathological examination of lung tissue biopsy materials by a bright-field method and polarized filter and using electron microscopy, the composition of dust in the lung tissue complied with the composition of industrial aerosol. It is formed during bauxite mining (aluminum, iron, and quartz compounds). High-resolution computed tomography (HRCT) and bronchoscopy can detect signs of exposure to industrial aerosol of complex composition represented by early interstitial parenchymal fibrosis and changes in bronchial mucosa. This is typical for individuals at risk of occupational respiratory diseases development without radiological features specific to pneumoconiosis. Before X-ray pattern formation, typical for pneumoconiosis, bronchitis syndrome and atrophic changes in the bronchial mucosa are developed. This happens in workers exposed to weakly-fibrogenic dust of a complex composition formed during the mining of bauxite. The changes are permanently observed long after the exposure to the dust factor has ceased.
Medical and social characteristic and occupational risk factors of employees of locomotive brigades
Authors: Zhidkova Elena A. , Gutor Ekaterina M. , Wilk Mikhail F. , Pankova Vera B. , Onishchenko Gennady G. , Gurevich Konstantin G.
Published: January 2021

Introduction. Drivers and assistant drivers directly manage rail transport. The number of employees of locomotive brigades in 2018 amounted to about 140 thousand people. A significant number of driver jobs and their assistants are characterized by third class working conditions. Purpose of the study. Study of medical and social characteristics and production risk factors of locomotive crew employees. Material and methods. In 2018, 7.6% of locomotive teams employees were interviewed from their full-time number using STEPS tool and questionnaire on production risk factors. The study was carried out on all railways of the Russian Federation. 10476 questionnaires are collected. Results. 55.5% of the respondents indicated their work schedule to be abnormal; 60% of workers reported about extra-working time. More than 50% of workers told earlier start of work, 43% said about later ends. 86% of respondents believed that work hurt their health. 96% of drivers complained about the low air temperature in the cabin during the winter period, 83% reported about the need to carry out repair works during the flight, 69% say about overheating in the house in the summer, 61% wrote about the need to make a lot of movements in the place during operation, 51% reported about noise, and 52% told about vibration. Conclusion. The working schedule of at least 50% of respondents is not optimal. More than 60% of workers note not good hygienic working conditions. The ongoing work of Russian Railways JSC on the modernization of the locomotive fleet partly eliminates some of the above-mentioned occupational risk factors, which adversely affect employees’ psychoemotional and physical condition of locomotive teams.
The risk assessment for employees working under different technologies of application of pesticides
Authors: Rakitskii Valery N. , Tarasova Liliya S. , Artemova Olga V. , Ilnitskaya Aleksandra V. , Fedorova Svetlana G.
Published: January 2021

Introduction. In recent years, agricultural production in Russia has increased at the expense of farms and personal subsidiary plots; farmers use chemical protection means - pesticides to protect crops. Farmers and users of private household plots are considered the leading risk group most exposed to pesticides during their application, transportation, and loading. At the same time, farmers and users do not have special training in the safe handling of pesticides. They do not undergo periodic medical examinations, which increases the risk of exposure to pesticides on their health. Purpose of work. Study of exposures of pesticides in the air of the working area and on the skin of workers when they use pesticides in private farms, farms on-field, and high garden crops; justification of the requirements for the safe use of pesticides in private farms and farms. Material and methods. The established exposure levels of pesticides in the air and on the skin were compared with hygiene standards calculated or experimentally set: MPC / OBUV (mg / m3) in the atmosphere of the working area and MPC/ODU (mg/cm2) of skin contamination. The exposure level risk was determined by the KBsumm. The risk of exposure to pesticides for the operator/farmer/user based on the absorbed dose, determined by the value of the safety factor - KBp, and exposure - Kbsumm, is considered acceptable when the value of KBsumm and KBp < 1. Results. The authors presented generalized results of the analysis of the risk of exposure to pesticides in terms of both exposure (KBsumm) and absorbed dose (KBp) in natural conditions when using 20 drugs on field and garden crops in private household plots and farms. The absorbed dose for farmers, calculated taking into account the work for 6 hours, when compared with ADI, in some cases, exceeded the permissible values. The risk of using two preparations in suspension concentrates and one preparation in the form of a nanoemulsion concentrate in terms of the absorbed dose during knapsack spraying of field crops in farms was higher than the acceptable one. Conclusion. The hygienic assessment of the risk of using pesticides of different hazard classes for all land application methods into the environment convinces us the actual hygienic situation to be determined mainly by the state of the equipment used, compliance with hygiene regulations. The degree of professional skills of operators, as well as the culture of pesticide use, are significant. In the future, the risk, especially in terms of the absorbed dose, must be calculated for users of private household plots and farmworkers, taking into account the differences in cultivated areas’ volumes.
Improvement in Survival Outcomes of Acute Lymphoblastic Leukemia Patients Treated With Berlin-Frankfurt-Munster 76/79 Protocol
Authors: Khansa Saleem  , Muhammad Ilyas  , Saad Razzaq  , Fahad Maqbool  , Qaiser Abbas  , Aneem Abdullah  , Abu Bakar Shahid
Published: January 2021

Introduction: Acute lymphoblastic leukemia (ALL) is a malignancy of the white blood cells and lymphoid lines of hematopoietic cells in the blood and bone marrow while lymphomas mostly involve the lymph nodes. This study showed the response rate of ALL treated with BFM (Berlin-Frankfurt-Munster) 76/79 protocol.

Aims & Objectives: To study the effects of WBC (White Blood Cells), age, and treatment protocols on the survival of ALL patients to BFM 76/79 protocol and other chemotherapy protocol.

Place and duration of study: 6 months retrospective study on 2015-2017 indoor patient data from INMOL Hospital Lahore, Pakistan.

Material & Methods: Data of 129 patients was assessed for eligibility, and 84 patients of ALL  selected. Clinical information of patients regarding Gender, Age, WBC, Fever, Hepatosplenomegaly, Lymphadenopathy, Bleeding, Bone Pain, Immunophenotype, Relapse, Death, and survival rates were recorded. Patients were grouped according to Age, WBC, Gender, and Immunophenotype. Patients were treated with BFM 76/79 Protocols and the remaining patients were treated with other protocols (CALGB, FLAG-TDA, Hyper-CVAD, EURO, COG, T-Cell ALL protocol, and ALL protocol 9111).

Results: Out of 84 patients, 55 (65.5%) patients were treated with Berlin-Frankfurt-Munster 76/79 protocol and the remaining 20 (23.81%) patients with other protocols. After the end of induction 64 (73.8%) patients achieved complete remission and 5 (5.95%) patients did not achieve Remission.

Conclusion:  Response rate of ALL (Acute Lymphoblastic Leukemia) patients treated with BFM 76/79 protocol was better than other protocols and possibly when risk adapted for male gender, WBC > 50 x 109/L and age> 30 years.
Az innovációs és tanulási képesség egyenlőtlenségei : A magyar kkv-k nemzetközi összehasonlításban
Authors: Makó Csaba , Illéssy Miklós , Heidrich Balázs
Published: January 2021

A tanulmány értékeli a magyar kkv-szektor innovációs teljesítményét. A szervezeti méret, a tanulási-abszorpciós képesség és az innováció „hármasa” képezi az elemzés központi tárgyát. Az eredmények szerint jelentős különbségek találhatók a régi és új EU-tagállamok innovációs teljesítményében. A kkv-szektor innovációs teljesítménye minden tagállamban elmarad a nagyvállalatokétól, azonban a régi tagállamokban a különbségek kisebbek a szervezeti méret szerint, mint az új tagállamokban. Az innovációs teljesítményben tapasztalható különbségek az egyes országok aggregált innovációs teljesítményét is kedvezőtlenül befolyásolják, vagyis ahol nagyobbak a különbségek a nagyvállalatok és a kkv-k között, ott az innovációs teljesítmény átlagos színvonala is kisebb. A humán, a strukturális és a kapcsolati tőkék külön-külön és együttesen is meghatározó szerepet játszanak a kkv-k tanulási és abszorpciós képességében és ezen keresztül az innovációs teljesítmény színvonalában.
Значение свободных экономических зон по улучшению инвестиционного потенциала региона
Authors: Камoлова А.
Published: January 2021

В статье рассматриваются перспективы инвестирования в свободные экономические зоны (СЭЗ) на территории Республики Узбекистан. Сделан корреляционный анализ влияния объема инвестиций на основные макроэкономические показатели. Рассматриваются теоретические и практические аспекты функционирования СЭЗ. Сделаны авторские выводы и предложения по улучшению инвестиционного потенциала региона и обеспечения стабильного функционирования СЭЗ.
Расчёт гидравлического удара в самодренируемых гелиоустановках
Authors: Рашидов Юсуф , Файзиев Зафар , Рашидов Карим
Published: January 2021

АННОТАЦИЯ

Целью исследования является выявление особенностей возникновения гидравлических ударов в самодренируемых гелиоустановках атмосферного типа при пуске и остановке циркуляционных насосов,вывод расчётных формул для вычисления их величины и выполнение практические расчётов для самодренируемых гелиоустановок применяемых на практике.

Установление расчётных формул для определения величины гидравлического удара было осуществлено теоретическим методом на основе теории Н.Е. Жуковского, а также путём составления уравнения Д.Бернулли для определения максимальной скорости истечения теплоносителя в дренажный бак, находящийся под атмосферным давлением.

Получены зависимости для расчёта прямого (полного) и непрямого (неполного) гидравлических ударов с разрывом и без разрыва сплошности потока при пуске и остановке циркуляционных насосов самодренируемых гелиоустановок. Выполнены практические расчёты с учётом характеристик самодренируемыхгелиоустановок 16-ти ведущих мировых производителей.

На величину гидравлического удара в самодренируемых гелиоустановках большое влияние оказывают электромеханические характеристики циркуляционных насосов. При проектировании самодренируемых гелиоустановок подбор циркуляционных насосов кроме основных их показателей (напор и расход) должен осуществляться также с учётом их электромеханических характеристик (мощность, число оборотов, вращающий момент на валу электродвигателя и момент инерции его ротора), влияющих на величины гидравлического удара.
ASPECTS OF CLASSROOM METHODS.
Authors: Nadirova Hilola
Published: January 2021

In this article says about to develop aspects, methods, approaches and techniques of Classroom Methods in foreign language teachers.Key words: develop, classroom methods, aspects, approaches, tachniques.
Changes in the spectrum of salivary cytokines in recurrent stomatitis in children
Authors: Murtazaev Alisher , Norbutaev Alisher
Published: January 2021

The concentration of the level of cytokines in saliva depends on the form of stomatitis, which is confirmed by the presence of a relationship between the concentrations of TNFα and IL-1β, and this relationship is direct and varies depending on the form of stomatitis, which indicates a violation of immunoregulatory mechanisms in chronic recurrent forms of stomatitis.
Распространенность кожных лейшманиозов среди населения в эндемичных районах Узбекистана
Authors: У.Т. Сувонкулов , Т.И. Муратов , М.Р. Баратова , Н.Х. Исламов , Л.А. Саламова , Р.А. Орипов , В.А. Мамиров
Published: January 2021

Согласно официальным данным, встречаемость кожных лейшманиозов за полседние 5 лет, в эндемичных районах Узбекистана заметно растет. Учитывая рост заболеваемости среди населения республики, необходимым является проведение ежегодного эпидемиологического анализа выявляемости и распространения данного заболевания, с целью своевременного контроля и профилактика. [1,4,5].
Симптоматик эпилепсияда когнитив бузилишларни психотерапевтик коррекцияси
Authors: Эрнаева Гуласал , Махаматджанова Нодира
Published: January 2021

Кўплаб неврологик касалликларда когнитив бузилишлар асосий касалликни асорати бўлиб келиши аниқланган. Шунингдек, когнитив бузилишлар беморларда эрта иш қобилятини юқотилишига ва ҳаёт сифатига салбий таъсир кўрсатишига олиб келади. Шундай экан беморларда когнитив функцияларни стимулловчи машқлар орқали деменция ривожланиб кетишини олдини олиш мумкун
Сочинение и подчинение в структуре сложного предложения
Authors: Закирова Махмуда , Боронов Икром
Published: January 2021

В данной статье рассматривается вопросы сочинения и подчинения в структуре сложного предложения. Статья состоит в выявлении особенностей типов синтаксической связи в структуре сложного предложения.
Норма ижодкорлигида юридик техникани қўллаш борасидаги хориж тажрибаси
Authors: Берлияров Шухрат
Published: January 2021

Мақолада ҳуқуқий фаолиятда юридик техникани қўллаш билан боғлиқ хорижий давлатларнинг тажрибалари уларнинг ҳуқуқий тизими, норматив-ҳуқуқий ҳужжатлари, ҳуқуқ ижодкорлиги, ҳуқуқни қўллаш амалиёти ҳамда нашр этилган монография, рисола ва ўқув қўлланмаларини ўрганиш асосида илмий таҳлил этилган.
Жамоат хавфсизлигини таъминлашда қилмишнинг жиноят эканлигини истисно этувчи айрим масалалар таҳлили
Authors: Ғиёсов Баҳриддин
Published: January 2021

Мазкур мақола Ўзбекистон Республикасида жамоат хавфсизлигини таъминлаш фаолиятини олиб борувчи ҳуқуқ-тартибот органларнинг ҳуқуқбузарликларни олдини олиш ва бартараф этишда куч ишлатиш, хусусан ўқотар қуролдан фойдаланиш ва қўллаш борасидаги амалиётини ўз ичига олади. Бундан ташқари, ҳуқуқни муҳофаза қилиш органлари қилмишнинг жиноийлигини истисно қиладиган ҳолатлар ҳақидаги жиноят-ҳуқуқий институтнинг фундаментал қоидаларини мустаҳкамлайди.
Особенности криминалистического познания доказательственной информации в расследовании преступлений против общественного порядка
Authors: Таджиев Азамат
Published: January 2021

В статье рассматриваются вопросы связанные с теорией доказательств в раскрытии и расследовании преступлений против общественного порядка посредством изучения теоретических аспектов криминалистического познания доказательственной информации, которая служит оптимизации алгоритма действий следователя, дознавателя и должностных лиц осуществляющих доследственную проверку направленную на повышение качества обнаружения, получения, фиксации, изучения и проверки доказательств указывающих на вину в совершении данного вида преступлений.
Давлат рамзларининг янги Ўзбекистонни янада ривожлантиришдаги аҳамияти
Authors: Мухамедов Ўткирбек , Саидов Бахром
Published: January 2021

Ўзбекистон Республикасининг давлат рамзлари бўлган давлат байроғи, герби ва мадҳияси, уларнинг қабул қилиниши, ҳуқуқий асоси, тавсифи, белгилари, янги Ўзбекистонни сиёсий, иқтисодий ва ижтимоий ривожлантиришдаги аҳамияти, суверен, тинчликпарвар мамлакат ёшларини ватанпарварлик руҳида тарбиялашда давлат рамзларининг ўрни ҳақидаги фикр-мулоҳазалар илгари сурилган
Исламское гражданское право – муамалат
Authors: Рахманов Абдумухтар
Published: January 2021

В статье рассмотрено исламское гражданское право начало которого складывается в основном во II веке Арабского халифата. Исламское право – это в значительной части частное право, исторически возникшее из отношений собственности, обмена, личных неимущественных связей. Особой и наиболее развитой его отраслью является «право личного статуса», основными институтами которого являются брак, развод, родство, материальное обеспечение семьи, обязанности по воспитанию семьи, наследование по закону, муамалат, опека, попечительство, ограничение правоспособности и т. д. Анализ основных положений собственно исламского права и общих положений, регулирующих отношения собственности, налоговую систему, торговлю и финансы, позволяет раскрыть сущность исламского законодательства, проследить его эволюцию в процессе исторического развития. В зоне распространения ислама, исламское право было и остается сводом законов и принципов, регулирующих жизнь уммы. Исламское законодательство рассмотрено, что, не только полностью сохраняет своё значение, но и играет все более важную роль в развитии исламской цивилизации.
The importance of physical culture and sports in student life
Authors: Gapparov Khafiz , Akhmedov Khikmatilla
Published: January 2021

The article discusses the concepts of physical culture and sports, the important task of which is strengthening and maintaining health, their importance in the life of students. It is also considered what role physical culture and sports play in student life, how it affects personality development and motivation for a healthy lifestyle of a student.
Competencia docente en la formación de emprendedores en un contexto de emergencia sanitaria
Authors: CARDENAS VASQUEZ YUDITH YESICA , LEDESMA CUADROS MILDRED JÉNICA
Published: January 2021

Competencia docente en la formación de emprendedores en un contexto de emergencia sanitaria
Importancia del manejo interdisciplinario de pacientes con Fisuras Labiopalatinas y Anemia de Blackfan Diamond. Reporte de caso: seguimiento a 2 años
Authors: Cisneros Hidalgo Cristhian Ariel , Sotomayor Guaman Gabriela , Bernal Pardo María del Pilar
Published: January 2021

Las fisuras labiopalatinas (FLP) son las malformaciones craneofaciales congénitas más comunes. La anemia de Diamond-Blackfan o anemia aneritroblástica es una hipoplasia congénita selectiva de la serie roja, asociada a alteraciones cardiacas, renales, malformaciones en manos, hipertelorismo y retraso en el crecimiento. La presentación de las FLP y pacientes con Anemia de Diamond-Blackfan es del 10.3%. Objetivo: Presentar un reporte de caso de un paciente de 12 años con anemia de Diamond-Blackfan y secuela de FLP de la Clínica Interdisciplinaria de LPH de la Pontificia Universidad Javeriana (Bogotá-Colombia) donde el abordaje interdisciplinario, el casomanejo del comportamiento y el apoyo psicológico brindado a la familia fueron fundamentales para lograr la adherencia, clarificar el diagnóstico y obtener los resultados terapéuticos esperados. Resultados: se logró la adherencia al tratamiento y el éxito de éste en apoyo con otras especialidades, permitiendo un seguimiento de 2 años. Conclusiones: El manejo multidisciplinario e interdisciplinario con especialidades odontológicas, médicas, y de la salud en general para el manejo de pacientes con FLP y síndromes asociados, resulta importante para el éxito en el tratamiento.
Reprobación escolar en el nivel medio superior y su relación con el autoconcepto en la adolescencia
Authors: Díaz Barajas Dámaris , Ruiz Olvera Abigail
Published: January 2021

Algunos de los problemas del sistema educativo nacional en su nivel medio superior son la deserción, la baja eficiencia terminal y el bajo rendimiento escolar, problemática asociada a los niveles de reprobación en sus alumnos. La reprobación escolar consiste en no aprobar una o varias materias en un determinado grado o nivel, lo cual se relaciona a elementos sociales y familiares, psicológicos, económicos, perfiles de ingreso limitados y falta de hábitos de estudio (Corzo s/f). Entre los factores personales se encuentra el autoconcepto, o conjunto de pensamientos y sentimientos genéricos que el individuo tiene de sí mismo. Esta investigación se plantea como objetivo determinar si existe relación entre la reprobación escolar y el autoconcepto. La metodología fue cuantitativa, con un diseño descriptivo correlacional, con 103 estudiantes de nivel bachillerato de una preparatoria pública de la ciudad de Morelia, Michoacán, México, quienes presentaban más de una materia reprobada. Se les aplicó la Escala de Autoconcepto AF5 de Tomas y Oliver (2004), validada para esta población por Díaz y Morales (2015), con un alpha de Cronbach de .775. Los resultados destacan una correlación significativa de carácter negativo entre el número de materias reprobadas y el autoconcepto en sus factores familiar y escolar.
Ethnic Identity Formation beyond Language: Reflexive Identification of Indigenous Children in Urban Schools
Authors: Moreno Medrano Luz María Stella
Published: January 2021

This paper examines the processes of identity formation of indigenous children in two urban schools in Jalisco, Mexico. By studying the processes of identity formation, I focus on understanding how indigenous children represent themselves within wider social discourses and dynamics of power that attempt to erase cultural differences. Drawing on ethnographic research conducted in two urban primary schools over a period of 14 months, the paper foregrounds indigenous children’s voices to illustrate their complex processes of selfidentification. The article demonstrates how children’s social and family networks, such as compadrazgos, shape ethnic identities. It also highlights how indigenous children feel a stronger attachment to their communities when they have the opportunity to participate in agricultural activities during holidays and learn from their grandparents and other family members. The analysis also highlights the silences, racism, and ethnic blindness that indigenous children face in urban schools. The paper calls for a reframing of educational services so that they recognize and reinforce ethnic identities rather than obfuscate them through the discourse of “equality”. Significantly, children’s voices open up a dialogue with those responsible for educational and social policies, in order to challenge racism in Mexican urban schools.
Trayectoria escolar y de vida de Angelo Cabrera y su lucha por el derecho a la educación
Authors: Ruiz Muñoz María Mercedes
Published: January 2021

Este trabajo presenta los resultados de una investigación acerca de la trayectoria escolar y de vida en contextos migratorios, así como de la lucha por el derecho a la educación. Mediante la voz del protagonista, resultado de entrevistas a profundidad y diálogos informales para construir, de manera conjunta, las tramas y las unidades discursivas (meta-categorías y categorías) propias de los estudios de corte cualitativo. El escrito da cuenta de la vida diaria de un migrante y de lo que hizo posible su derecho a la educación. Angelo Cabrera descubrió que la educación es un derecho humano y exigió su acceso y permanencia a la educación superior. Durante su trayectoria escolar, el atentado terrorista en la Ciudad de Nueva York, el 11 de septiembre del 2001 generó una política anti migratoria y que las universidades aplicaran el pago de colegiatura “fuera del estado” a los estudiantes migrantes. Ante eso, un grupo de jóvenes inmigrantes mexicanos decidió salir de la sombra para dar la cara para luchar por el derecho a la educación superior. Este trabajo permite dar cuenta de la configuración del sujeto de derecho a partir de la exigibilidad en la lucha social y la justiciabilidad en el terreno jurídico.