bluuebunny/crossref_metadata_2025 huggingface dataset:
An immunoproteomic approach revealing peptides from Sporothrix brasiliensis that induce a cellular immune response in subcutaneous sporotrichosis
Authors: de Almeida José Roberto Fogaça , Jannuzzi Grasielle Pereira , Kaihami Gilberto Hideo , Breda Leandro Carvalho Dantas , Ferreira Karen Spadari , de Almeida Sandro Rogério
Published: March 2018

Sporothrix brasiliensis is the most virulent fungus of the Sporothrix complex and is the main species recovered in the sporotrichosis zoonotic hyperendemic area in Rio de Janeiro. A vaccine against S. brasiliensis could improve the current sporotrichosis situation. Here, we show 3 peptides from S. brasiliensis immunogenic proteins that have a higher likelihood for engaging MHC-class II molecules. We investigated the efficiency of the peptides as vaccines for preventing subcutaneous sporotrichosis. In this study, we observed a decrease in lesion diameters in peptide-immunized mice, showing that the peptides could induce a protective immune response against subcutaneous sporotrichosis. ZR8 peptide is from the GP70 protein, the main antigen of the Sporothrix complex, and was the best potential vaccine candidate by increasing CD4+ T cells and higher levels of IFN-γ, IL-17A and IL-1β characterizing a strong cellular immune response. This immune environment induced a higher number of neutrophils in lesions that are associated with fungus clearance. These results indicated that the ZR8 peptide induces a protective immune response against subcutaneous sporotrichosis and is a vaccine candidate against S. brasiliensis infection.
Introduction to Dienamine Chemistry
Authors: Anebouselvy Kengadarane , Ramachary Dhevalapally B.
Published: March 2018

This chapter gives a description of dienamine chemistry from a general perspective in terms of its developmental growth, inherent properties, behavioral pattern and its significance in Diels–Alder chemistry. It also gives a glimpse of the different types of dienamine intermediates.
Synthesis and Applications of Preformed Dienamines
Authors: Anebouselvy Kengadarane , Ramachary Dhevalapally B.
Published: March 2018

This chapter compiles the reports available on the preformed stoichiometric dienamines, 1-aminobuta-1,3-dienes and 2-aminobuta-1,3-dienes, in the literature. It emphasizes the various synthetic methods existing for these preformed dienamine intermediates and their application as electron-rich dienes in Diels–Alder reactions with various dienophiles. This chapter also includes a few metal-catalyzed methods for the preparation of some preformed dienamine intermediates. A few of the preformed dienamine species are even employed in the synthesis of pharmaceutically important compounds.
Asymmetric α-Selective and Remote γ-Selective Functionalization of Enals and Enones Through Serebryakov–Jørgensen Dienamines (1-Aminobuta-1,3-Dienes)
Authors: Anebouselvy Kengadarane , Ramachary Dhevalapally B.
Published: March 2018

Serebryakov–Jørgensen dienamine intermediates derived from enals, cyclic enones and allylic ketones with the aid of amine catalysts have found widespread applications in some highly appealing α-selective functionalizations and, far more intriguing, γ-selective functionalizations in recent times. Intramolecular Baylis–Hillman type reactions, asymmetric aza-Morita–Baylis–Hillman type products, chiral Michael adducts from addition to nitroolefins, intramolecular Rauhut–Currier cyclizations for the construction of chiral cyclopentenals, the asymmetric synthesis of cyclopentyl[b]indolines via the SN1 alkylation reaction of γ,γ-disubstituted α,β-unsaturated aldehydes with 3-indolylmethanols and the asymmetric benzoyloxylation of α-branched enals were attainable as α-selective functionalization. The category of γ-selective functionalization encompassed the asymmetric amination of α,β-unsaturated aldehydes, the synthesis of a key intermediate for α-tocopherol, aldol reactions with aldehydes, isatins (for the enantioselective synthesis of 3-substituted 3-hydroxyoxindole derivatives) and α-ketoesters (involving hydrogen-bond-directing dienamine catalysis), alkylation of α-branched enals, and the enantioselective Michael addition of cyclic enones to nitroalkenes and allyl alkyl ketones to maleimides. Moreover, γ-propargylation, γ-oxyamination and asymmetric γ-allylation of α,β-unsaturated aldehydes were achieved by combined dienamine and transition-metal catalysis. Enantioselective γ-alkylation of enals was also driven by the direct photoexcitation of dienamine intermediates. Further, γ-selective nitrone formation from an enal via a redox reaction is highlighted in this chapter.
Theoretical Chemistry for Electronic Excited States
Authors: Robb Michael A
Published: March 2018

Over the past few decades, experimental excited state chemistry has moved into the femtochemistry era, where time resolution is short enough to resolve nuclear dynamics. Recently, the time resolution has moved into the attosecond domain, where electronic motion can be resolved as well. Theoretical chemistry is becoming an essential partner in such experimental investigations; not only for the interpretation of the results, but also to suggest new experiments.

This book provides an integrated approach. The three main facets of excited-state theoretical chemistry; namely, mechanism, which focuses on the shape of the potential surface along the reaction path, multi-state electronic structure methods, and non-adiabatic dynamics, have been brought together into one volume. Theoretical Chemistry for Electronic Excited States is aimed at both theorists and experimentalists, involved in theoretical chemistry, in electronic structure computations and in molecular dynamics. The book will provide both with the knowledge and understanding to discover ways to work together more closely through its unified approach.
Toward universal protein post-translational modification detection in high throughput format
Authors: Härmä Harri , Tong-Ochoa Natalia , van Adrichem Arjan J. , Jelesarov Ilian , Wennerberg Krister , Kopra Kari
Published: March 2018

Universal leucine-zipper based peptide-break technology for the detection of various enzymatic protein post-translational modifications using a luminescent high throughput approach.
A neural network potential energy surface for the F + CH4reaction including multiple channels based on coupled cluster theory
Authors: Chen Jun , Xu Xin , Liu Shu , Zhang Dong H.
Published: March 2018

We report here a new global and full dimensional potential energy surface (PES) for the F + CH4reaction.
Supported Fe/MnOx catalyst with Ag doping for remarkably enhanced catalytic activity in Fischer–Tropsch synthesis
Authors: Xu Yuebing , Jia Xinli , Liu Xiaohao
Published: March 2018

The role of Ag in the promotion of the FTS performance and the evolutions of structure and phase over the Fe/MnOx catalyst has been clearly elucidated.
Systems analysis of the genetic interaction network of yeast molecular chaperones
Authors: Rizzolo Kamran , Kumar Ashwani , Kakihara Yoshito , Phanse Sadhna , Minic Zoran , Snider Jamie , Stagljar Igor , Zilles Sandra , Babu Mohan , Houry Walid A.
Published: March 2018

Many molecular chaperones were found to be central drivers of the yeast whole genome genetic interaction network topology.
High-voltage performance of concentration-gradient Li[Ni0.6Co0.2Mn0.2]O2 layered oxide cathode materials for lithium batteries
Authors: Chen Xianglei , Jia Xiaobo , Qu Yanyu , Li De , Chen Daming , Chen Yong
Published: March 2018

High-voltage performance concentration-gradient Li[Ni0.6Co0.2Mn0.2]O2 (CG-NCM622) layered oxide cathodes consisting of Li[Ni0.8Co0.1Mn0.1]O2 cores and stable outer layers of Li[Ni1/3Co1/3Mn1/3]O2 were synthesized via co-precipitation.
A sensitive and selective sensor for picric acid detection with a fluorescence switching response
Authors: Nath Subrata , Pathak Suraj Kumar , Pradhan Balaram , Gupta Ravindra Kumar , Reddy K. Anki , Krishnamoorthy G. , Achalkumar Ammathnadu S.
Published: March 2018

Low molecular weight organogelator for the detection of picric acid.
One-step synthesis of hollow C-NiCo2S4 nanostructures for high-performance supercapacitor electrodes
Authors: Mohamed Saad Gomaa , Hussain Iftikhar , Shim Jae-Jin
Published: March 2018

A highly conductive mesoporous hollow-nanostructured C-NiCo2S4 synthesized by a one-step procedure exhibited a remarkable electrochemical activity and stability for supercapacitor applications.
Bimetallic junction mediated synthesis of multilayer graphene edges towards ultrahigh capacity for lithium ion batteries
Authors: Cho Sanghyun , Jung Insub , Jang Hee-Jeong , Liu Lichun , Park Sungho
Published: March 2018

In this work, we report on a novel strategy to synthesize high-density graphene edges on a vertically-aligned nanorod array substrate based on multiple segmented Ni–Au units.
Stemmed DNA nanostructure for the selective delivery of therapeutics
Authors: Jin H. , Kim M. G. , Ko S. B. , Kim D. H. , Lee B. J. , Macgregor, Jr. R. B. , Shim G. , Oh Y. K.
Published: March 2018

A stemmed DNA nanostructure entrapping therapeutics was designed for selective delivery.
Carbon dioxide as a green carbon source for the synthesis of carbon cages encapsulating porous silicon as high performance lithium-ion battery anodes
Authors: Zhang Yaguang , Du Ning , Chen Yifan , Lin Yangfan , Jiang Jinwei , He Yuanhong , Lei Yu , Yang Deren
Published: March 2018

CO2, for the first time, was used as a green carbon source for synthesizing carbon cages encapsulating porous Si as high performance lithium-ion battery anodes.
Transfection efficiencies of α-tocopherylated cationic gemini lipids with hydroxyethyl bearing headgroups under high serum conditions
Authors: Maiti Bappa , Kamra Mohini , Karande Anjali A. , Bhattacharya Santanu
Published: March 2018

Liposomal gene transfection under high serum conditions.
Preliminary characterization of the structure and immunostimulatory and anti-aging properties of the polysaccharide fraction ofHaematococcus pluvialis
Authors: Liu Xiaojuan , Zhang Miao , Liu Han , Zhou Aimei , Cao Yong , Liu Xin
Published: March 2018

HPP-c3-s1 is a pyranose with an average molecular weights of 23 413 kDa, which exhibited siginificant immunomodulatory and anti-aging activities.
Vancomycin-loaded titanium coatings with an interconnected micro-patterned structure for prophylaxis of infections: an in vivo study
Authors: Zhang Hao , Wang Guangchao , Liu Peizhao , Tong Dake , Ding Chen , Zhang Zequan , Xie Youtao , Tang Hao , Ji Fang
Published: March 2018

Vancomycin-loaded titanium coatings with an interconnected micro-patterned structure for prophylaxis of titanium implant associated infection.
Comprehensive two-dimensional ion chromatography (2D-IC) coupled to a post-column photochemical fluorescence detection system for determination of neonicotinoids (imidacloprid and clothianidin) in food samples
Authors: Muhammad Nadeem , Wang Fenglian , Subhani Qamar , Zhao Qiming , Qadir Muhammad Abdul , Cui Hairong , Zhu Yan
Published: March 2018

A 2D-IC system was successfully fabricated for clean isocratic chromatographic separations and sensitive post column UV induced fluorescence determination of two NNIs in six complex food samples.
Insight into catalytic reduction of CO2to methane with silanes using Brookhart's cationic Ir(iii) pincer complex
Authors: Fang Shaoqin , Chen Hongcai , Wei Haiyan
Published: March 2018

The transformation of CO2and silanes to methane catalyzed by a cationic Ir–pincer complex is investigated and divided into four reducing steps. The first step is the rate-determining step of the overall catalytic cycle.
Cobalt layered double hydroxide nanosheets synthesized in water–methanol solution as oxygen evolution electrocatalysts
Authors: Xu Xiao , Zhong Zhou , Yan Xiaomei , Kang Longtian , Yao Jiannian
Published: March 2018

Ultrathin Co LDHs synthesizedviaa one-pot reaction of cobalt(ii) nitrate with 2-methylimidazole in water–methanol exhibit outstanding OER performance.
Highly selective and sensitive chemoresistive humidity sensors based on rGO/MoS2 van der Waals composites
Authors: Park Seo Yun , Kim Yeon Hoo , Lee Seon Yong , Sohn Woonbae , Lee Jung Eun , Kim Do Hong , Shim Young-Seok , Kwon Ki Chang , Choi Kyoung Soon , Yoo Hee Joun , Suh Jun Min , Ko Museok , Lee Jong-Heun , Lee Mi Jung , Kim Soo Young , Lee Min Hyung , Jang Ho Won
Published: March 2018

Sensors based on 2D rGO/2D MoS2 van der Waals hybrid composites exhibited high sensitivity, extreme selectivity, fast response/recovery, and good reliability to humidity detection.
Nanoengineered hollow mesoporous silica nanoparticles for the delivery of antimicrobial proteins into biofilms
Authors: Xu Chun , He Yan , Li Zhihao , Ahmad Nor Yusilawati , Ye Qingsong
Published: March 2018

Hollow mesoporous silica nanoparticles with large cone-shaped pores delivered antimicrobial proteins into biofilms and enhanced the antimicrobial activities.
A PPy/Cu2O molecularly imprinted composite film-based visible light-responsive photoelectrochemical sensor for microcystin-LR
Authors: Chen Junli , Gao Pan , Wang Hai , Han Lifeng , Zhang Yonghui , Wang Peiyuan , Jia Nengqin
Published: March 2018

In this study, a visible light-responsive photoelectrochemical (PEC) sensor based on a PPy/Cu2O molecularly imprinted composite film for microcystin-LR (MC-LR) has been fabricated.
A high-throughput method for multi-element determination in green coffee beans using diluted nitric acid and ultrasound energy
Authors: de Gois Jefferson S. , Lucena Izylla O. , Cezario Paulo S. de O. , da Silva Arnaldo P. , Lima Igor C. A. , Luna Aderval S.
Published: March 2018

This work describes the multivariate development of a straightforward method for multi-element determination based on the use of diluted nitric acid and UAE followed by determination using ICP-OES.
Lewis-base-catalysed selective reductions of ynones with a mild hydride donor
Authors: Schömberg F. , Zi Y. , Vilotijevic I.
Published: March 2018

Nucleophilic phosphines catalyze efficient 1,2-reductions of ynones employing pinacolborane as a mild hydride donor in the presence of alcohol additives.
Mechanism of protein–RNA recognition: analysis based on the statistical mechanics of hydration
Authors: Hayashi Tomohiko , Matsuda Tomoaki , Nagata Takashi , Katahira Masato , Kinoshita Masahiro
Published: March 2018

We investigate the RBD1–r(GUAGU) binding as a case study using all-atom models for the biomolecules, molecular models for water, and the currently most reliable statistical–mechanical method.
Detecting order and lateral pressure at biomimetic interfaces using a mechanosensitive second-harmonic-generation probe
Authors: Licari Giuseppe , Beckwith Joseph S. , Soleimanpour Saeideh , Matile Stefan , Vauthey Eric
Published: March 2018

A mechanosensitive harmonophore is used to probe the order and lateral pressure in phospholipid monolayers by surface-second harmonic generation.
Hierarchically porous Fe–N–C nanospindles derived from a porphyrinic coordination network for oxygen reduction reaction
Authors: Hua Xing , Luo Jin , Shen Chencheng , Chen Shengli
Published: March 2018

NaCl-assisted pyrolysis of an Fe porphyrinic coordination network combined with concentrated-sulfuric-acid post-activation results in a hierarchically porous Fe–N–C nanospindle catalyst.
Synthesis and radiometric evaluation of diglycolamide functionalized mesoporous silica for the chromatographic separation of actinides Th, Pa and U
Authors: Hopkins Philip D. , Mastren Tara , Florek Justyna , Copping Roy , Brugh Mark , John Kevin D. , Nortier Meiring F. , Birnbaum Eva R. , Kleitz Freddy , Fassbender Michael E.
Published: March 2018

Grafting of DGA on mesoporous silica affords a sorbent with the potential to separate U from Pa and Th.
Statistical analysis of multi-dimensional, temporal gene expression of stem cells to elucidate colony size-dependent neural differentiation
Authors: Joshi Ramila , Fuller Brendan , Li Jun , Tavana Hossein
Published: March 2018

We established a three-step statistical approach to elucidate specific sets of genes that regulate colony size-mediated neural differentiation of stem cells.
Synthesis of ultrathin Ni nanosheets for semihydrogenation of phenylacetylene to styrene under mild conditions
Authors: Yu Jing-Wen , Wang Xin-Yu , Yuan Chen-Yue , Li Wei-Zhen , Wang Yu-Hao , Zhang Ya-Wen
Published: March 2018

Ultrathin Ni nanosheets were synthesized using a solvothermal method. The Ni nanosheets showed 88.0–92.0% selectivity towards stylene in phenylacetylene semihydrogenation reaction under mild conditions.
Correction: Four new carbazole alkaloids from Murraya koenigii that display anti-inflammatory and anti-microbial activities
Authors: Nalli Yedukondalu , Khajuria Vidushi , Gupta Shilpa , Arora Palak , Riyaz-Ul-Hassan Syed , Ahmed Zabeer , Ali Asif
Published: March 2018

Correction for ‘Four new carbazole alkaloids from Murraya koenigii that display anti-inflammatory and anti-microbial activities’ by Yedukondalu Nalli et al., Org. Biomol. Chem., 2016, 14, 3322–3332.
The effect of phosphate buffer on improving the performance of autothermal thermophilic aerobic digestion for sewage sludge
Authors: Jin Ningben
Published: March 2018

Enhancement of autothermal thermophilic aerobic digestion for sewage sludge by the addition of phosphate buffer.
Sustainable rose multiflora derived nitrogen/oxygen-enriched micro-/mesoporous carbon as a low-cost competitive electrode towards high-performance electrochemical supercapacitors
Authors: Chen Qiuli , Sun Jinfeng , Wang Zhengluo , Zhao Zhiwei , Zhang Yanru , Liu Yang , Hou Linrui , Yuan Changzhou
Published: March 2018

Hierarchical micro-/mesoporous N/O-enriched carbon was scalably fabricated, and exhibited high gravimetric/volumetric capacitances, a large energy density and long-term cycling stability for supercapacitors with aqueous and organic electrolytes.
Porous aromatic framework with mesopores as a platform for a super-efficient heterogeneous Pd-based organometallic catalysis
Authors: Jing Li-Ping , Sun Jin-Shi , Sun Fuxing , Chen Peng , Zhu Guangshan
Published: March 2018

A porous aromatic framework with mesopores was used as a platform for an immobilized Pd catalyst with superb catalytic activity and size selectivity for the Suzuki–Miyaura coupling reaction.
Dual hierarchical particle jetting of a particle ring undergoing radial explosion
Authors: Xue Kun , Du Kaiyuan , Shi Xiaoliang , Gan Yixiang , Bai Chunhua
Published: March 2018

We study experimentally the formation of a dual hierarchical jetting pattern in dry dense particle media subjected to the radially divergent shock loadings in a radial Hele-Shaw cell.
Azo-linked porous organic polymers: robust and time-efficient synthesisviaNaBH4-mediated reductive homocoupling on polynitro monomers and adsorption capacity towards aniline in water
Authors: Zhou Jin-Xiu , Luo Xian-Sheng , Liu Xiangxiang , Qiao Yan , Wang Pengfei , Mecerreyes David , Bogliotti Nicolas , Chen Shi-Lu , Huang Mu-Hua
Published: March 2018

Time-efficient synthetic methods of porous organic polymers are searched in order to extend the applications of these materials.
Dual hydrophobic grafted chains facilitating quaternary ammonium aggregations of hydroxide conducting polymers: a theoretical and experimental investigation
Authors: Ran Jin , Fu Cenfeng , Ding Liang , Cao Pengrui , Xu Tongwen
Published: March 2018

Dual grafted chains promote the effective aggregations of quaternary ammonium groups on the backbone.
Ionic liquids as an efficient medium for the mechanochemical synthesis of α-AlH3 nano-composites
Authors: Duan C. W. , Hu L. X. , Ma J. L.
Published: March 2018

Aluminum hydride (AlH3) is one of the most promising hydrogen storage materials that has a high theoretical hydrogen storage capacity (10.08 wt%) and relatively low dehydriding temperature (100–200 °C).
Robust platform for water harvesting and directional transport
Authors: Luo Hu , Lu Yao , Yin Shaohui , Huang Shuai , Song Jinlong , Chen Faze , Chen Fengjun , Carmalt Claire J. , Parkin Ivan P.
Published: March 2018

Water harvesting is used for transforming moisture into available water resources in regions that suffer water scarcity.
Enhanced multi-lineage differentiation of human mesenchymal stem/stromal cells within poly(N-isopropylacrylamide-acrylic acid) microgel-formed three-dimensional constructs
Authors: Zhang Jiabin , Yun Seonho , Bi Jingxiu , Dai Sheng , Du Yuguang , Zannettino Andrew C. W. , Zhang Hu
Published: March 2018

hMSCs derived from normal donors induced multi-lineage differentiation within thermosensitive poly(N-isopropylacrylamide-co-acrylic acid) microgel-formed 3D constructs.
Templating nanotraffic light – dynamic tricoloured blinking silver nanoclusters on a graphene oxide film
Authors: Lim S. X. , Lee Y. Z. , Gao N. , Lu J. , Xu Q. , Tok E. S. , Sow C. H.
Published: March 2018

Laser initiated site selective formation of dynamic tri-colour blinking silver nanoparticles on a transparent, flexible GO thin film.
Homometallic Ln(iii)-complexes from an ILCT ligand with sensitized vis-NIR emission, excitation-dependent PL color tuning and white-light emission
Authors: Liao Wei-Ming , Li Chao-Jie , Wu Xiangwen , Zhang Jian-Hua , Wang Zheng , Wang Hai-Ping , Fan Ya-Nan , Pan Mei , Su Cheng-Yong
Published: March 2018

Homometallic Ln(iii)-complexes with sensitized vis-NIR emission and excitation-dependent PL color tuning were achieved from an ILCT ligand.
Sub-5 nm structured films by hydrogen bonded siloxane liquid crystals and block copolymers
Authors: Nickmans Koen , Verpaalen Rob C. P. , Murphy Jeffrey N. , Schenning Albert P. H. J.
Published: March 2018

Polymeric supramolecules were prepared using hydrogen-bonding oligo(dimethylsiloxane)-based liquid crystals and poly(4-vinylpyridine) homopolymer or poly(styrene)-b-poly(4-vinylpyridine) block copolymer. These materials form glassy, hybrid organic/inorganic thin films with sub-5 nm features.
Hydrogen-bonded azaphenacene: a strategy for the organization of π-conjugated materials
Authors: Gómez Paula , Georgakopoulos Stamatis , Cerón José Pedro , da Silva Iván , Más-Montoya Miriam , Pérez José , Tárraga Alberto , Curiel David
Published: March 2018

Molecular design for the self-assembly of molecular materials.
Decentralised frequency‐based control of a population of heterogeneous ACs without power oscillations
Authors: Shi Xinli , Yu Jie , Cao Jinde , Yong Taiyou
Published: March 2018

In power system, the control performance deteriorates due to the penetration of the fluctuating renewable generation if no advanced control strategy is implemented. In this study, the authors investigate a class of thermostatically controlled loads – air conditioners (ACs) – to provide fast frequency regulation service in system contingencies by switching ON/OFF state based on the system frequency deviation in a decentralised way. First, an estimation of the steady‐state aggregate power of a population of heterogeneous ACs is derived corresponding to the ambient temperature, and the power overshoot caused by a safe protocol (SP) is discussed analytically, both of which are verified by simulations. Then, a decentralised frequency‐based control strategy is designed and a multi‐stage frequency responsive model is implemented implicitly. An SP with the timer is introduced in the strategy in order to eliminate the power oscillations during the load pick‐up period. Finally, the proposed strategy is incorporated into the primary control of the power system to provide fast frequency regulation service in power contingencies. Comparing with other decentralised strategies, the proposed method can obtain a lower‐frequency deviation and the smoothest demand trajectory without long‐term power oscillations when a power contingency occurs. Meanwhile, the comfort of the consumers is guaranteed during the demand response.
Wide‐area measurement system‐based model‐free approach of post‐fault rotor angle trajectory prediction for on‐line transient instability detection
Authors: Huang Dan , Yang Xiuyuan , Chen Shuyong , Meng Tao
Published: March 2018

In order to achieve adequate time for emergency control against transient instability, a scheme to predict the post‐fault rotor angle trajectory based on the grey Verhulst self‐memory model is provided. The proposed scheme is model free and only uses wide‐area measurement system data to provide timely, reliable information about the transient rotor angle stability. Moreover, the scheme is model‐parameter‐adaptive and takes full consideration of the non‐linearity as well as uncertainty of power systems. Firstly, the grey Verhulst self‐memory prediction model is presented to cope with the strong non‐linear and non‐autonomous nature of the power system. Secondly, the equal dimension and new information data model as well as the rolling prediction method are adopted to improve adaptability and robustness of prediction. Investigations with the IEEE‐39 bus system and NCE China power system indicate that the proposed prediction scheme gives better prediction performance compared with the other two prediction methods, i.e. grey Verhulst prediction and auto‐regressive prediction. Furthermore, combined with equal area criterion based on the severely disturbed generator pair, the proposed prediction scheme is conducted to detect transient instability. Simulation results indicate that the proposed prediction scheme is effective for prediction of transient stability.
Single‐phase high‐impedance fault protection for low‐resistance grounded distribution network
Authors: Tang Tao , Huang Chun , Hua Leng , Zhu Jiran , Zhang Zhidan
Published: March 2018

After a single‐phase high‐impedance fault (HIF) for low‐resistance grounded distribution network (LRGDN) occurs, fault current level is very low and cannot be detected by conventional overcurrent relays. In this study, composite power of each feeder which is composed of complex power and its conjugate is defined, and a HIF protection method based on the composite power of each feeder is presented. For a sound feeder, the phase angle of the composite power is equal to 0, and its amplitude is approximately 0. However, for the faulty feeder, the phase angle of the composite power is π, and its amplitude is much greater than 0. Base on the above significant difference, the protection criterion for HIFs in the LGRDN can be obtained. Theory analysis and simulation results show that the proposed method does not need to check the polarities of the zero‐sequence current transformers and is able to remove faulty feeder reliably. Besides, the protection can accurately operate for HIFs in the case of noise interference and unbalanced current. The experimental results based on RTDS also show the efficiency of the proposed method.
Active stabilisation design of DC–DC converters with constant power load using a sampled discrete‐time model: stability analysis and experimental verification
Authors: Gavagsaz‐Ghoachani Roghayeh , Saublet Louis‐Marie , Phattanasak Matheepot , Martin Jean‐Philippe , Nahid‐mobarakeh Babak , Pierfederici Serge
Published: March 2018

Instabilities of cascade converters with an LC filter in between in power electronic systems have been known, and many answers have been proposed. The load converters are tightly regulated, acting as constant power loads (CPLs). Average models are generally utilised to study the behavior of the converters. For embedded applications, the weight and the volume should be reduced. Consequently, in this case, the limitations of the average method are reached when the cut‐off frequency of the LC input filter is close to the switching frequency. Then, other tools are necessary to study this type of system. To overcome this problem, a discrete‐time model was developed to study the behavior of the system, taking into account the switching effect. The aim was to enlarge the power range of the stability zone for a DC system composed of a DC–DC boost converter as a source converter, which was connected to the power load via an LC input filter. For this purpose, a stabilisation expression is integrated in the command of the source converter. The stability analysis by the eigenvalues of the system is described using the proposed model. Simulation and experimental results are discussed to verify the proposed stabiliser in different cases.
Particle filter for track‐before‐detect of a target with unknown amplitude viewed against a structured scene
Authors: Rollason Malcolm , Salmond David
Published: March 2018

Track‐before‐detect methods operate directly upon raw sensor signals without a separate, explicit detection stage. An efficient implementation of a Bayesian track‐before‐detect particle filter is described for tracking of a single target in a sequence of images. The filter produces a sample‐based representation of the probability density function of the target state from raw pixel levels. An indication of the probability that the target is present is also provided. Spatial differentiation of the pixel array data allows objects to be tracked when viewed against a general scene with additive noise. Simulated results illustrate that a dim point target of unknown amplitude, which has become spatially blurred, may be tracked through a sequence of structured images. Detection sensitivity is established using simulated results. The novel aspect of the work is the efficient implementation – in particular, the calculation of the probability of the target being present.
Algorithm to identify the optimal perturbation based on the net basin‐of‐state of perturbed states in Boolean network
Authors: Shen Liangzhong , Zan Xiangzhen , Liu Wenbin
Published: March 2018

Boolean networks are widely used to model gene regulatory networks and to design therapeutic intervention strategies to affect the long‐term behavior of systems. Here, the authors investigate the 1 bit perturbation, which falls under the category of structural intervention. The authors’ idea is that, if and only if a perturbed state evolves from a desirable attractor to an undesirable attractor or from an undesirable attractor to a desirable attractor, then the size of basin of attractor of a desirable attractor may decrease or increase. In this case, if the authors obtain the net BOS of the perturbed states, they can quickly obtain the optimal 1 bit perturbation by finding the maximum value of perturbation gain. Results from both synthetic and real biological networks show that the proposed algorithm is not only simpler and but also performs better than the previous basin‐of‐states (BOS)‐based algorithm by Hu et al..
Model predictive control for reduced matrix converter with transformer DC magnetic bias suppression
Authors: Song Wei‐Zhang , Liu Jiang , Gao Da‐Qing , Wu Feng‐Jun , Wang You‐Yun
Published: March 2018

This study presents a model predictive control (MPC) considering transformer DC magnetic bias for a reduced matrix converter (RMC). The control scheme selects the switching state that minimises the error in the output current and input instantaneous reactive according to their reference values; furthermore, the pulse sequence in MPC has been re‐distributed to suppress the DC magnetic bias in transformer for RMC. MPC also presents stronger immunity to the influence of abnormal input voltage than bipolar space vector modulation strategy. Moreover, the simple performance comparison between RMC and pulse‐width modulated rectifier + dual active bridge was provided. The feasibility and validity of the proposed control scheme in an RMC has been verified by simulation results.
Turn‐on fluorescent probe for Cd2+ detection by gold nanoclusters/graphene oxide nanocomplex
Authors: Ju Cheng , Gong Xiang , Song Wenhao , Zhao Yu , Li Ruijun
Published: March 2018

This work reported the fabrication of bovine serum albumin stabilised gold nanoclusters (BSA‐Au NCs)–graphene oxide nanocomplex (BSA‐Au NCs‐GO) as a ‘turn‐on’ fluorescent probe for the detection of Cd2+. The prepared BSA‐Au NCs showed an intense red fluorescence, and the fluorescence of BSA‐Au NCs was reduced significantly by graphene oxide due to its excellent quenching properties. However, in the presence of 65 µmol l−1 Cd2+, the fluorescence intensity recovered to 82.5% of the intensity of BSA‐Au NCs, and the fluorescence intensity increased 1.3‐fold relative to the BSA‐Au NCs‐GO nanocomplex. This proposed probe expands the application of BSA‐Au NCs, which can be used as a reversible fluorescence nanoswitch for inexpensive, label free and simple detection of Cd2+ in the aqueous samples.
Controllable synthesis of TiO2/ATO conductive composite: effects of TiO2 surface properties
Authors: Li Xue , Qian Jianhua , Tang Ke , Xu Jiasheng
Published: March 2018

The effect of the TiO2 surface property on the conductivity of TiO2/antimony‐doped tin oxide (ATO) has been revealed by the substrate modification with SiO2 and ZrO2. Their morphology, structural, and electric characteristics were investigated through field emission scanning electron microscopy, transmission electron microscopy, X‐ray diffraction, X‐ray photoelectron spectroscopy, and electrochemical impedance spectra. The surface character of the raw and modified TiO2 particles in water was investigated. The results indicated that the negatively charged substrate (−29.7 mV) was formed through the incorporation of SiO2 coating, which facilitated the uniform deposition of positively charged ATO precursors further significantly improved the conductivity of TiO2/ATO composite. Conversely, the conductivity of TiO2/ZrO2–ATO composite decreased due to the increase of electrostatic repulsion from the positively charged surface (+55.3 mV) of the substrate. The results confirmed the feasibility of the method proposed in this work.
Searching for supernovae in the multiply-imaged galaxies behind the gravitational telescope A370
Authors: Petrushevska T. , Goobar A. , Lagattuta D. J. , Amanullah R. , Hangard L. , Fabbro S. , Lidman C. , Paech K. , Richard J. , Kneib J. P.
Published: March 2018

Aims. Strong lensing by massive galaxy clusters can provide magnification of the flux and even multiple images of the galaxies that lie behind them. This phenomenon facilitates observations of high-redshift supernovae (SNe) that would otherwise remain undetected. Type Ia supernovae (SNe Ia) detections are of particular interest because of their standard brightness, since they can be used to improve either cluster lensing models or cosmological parameter measurements.

Methods. We present a ground-based, near-infrared search for lensed SNe behind the galaxy cluster Abell 370. Our survey was based on 15 epochs of J-band observations with the HAWK-I instrument on the Very Large Telescope (VLT). We use Hubble Space Telescope (HST) photometry to infer the global properties of the multiply-imaged galaxies. Using a recently published lensing model of Abell 370, we also present the predicted magnifications and time delays between the images.

Results. In our survey, we did not discover any live SNe from the 13 lensed galaxies with 47 multiple images behind Abell 370. This is consistent with the expectation of 0.09 ± 0.02 SNe calculated based on the measured star formation rate. We compare the expectations of discovering strongly lensed SNe in our survey and that performed with HST during the Hubble Frontier Fields (HFF) programme. We also show the expectations of search campaigns that can be conducted with future facilities, such as the James Webb Space Telescope (JWST) or the Wide-Field Infrared Survey Telescope (WFIRST). We show that the NIRCam instrument aboard the JWST will be sensitive to most SN multiple images in the strongly lensed galaxies and thus will be able to measure their time delays if observations are scheduled accordingly.
Interstellar bromine abundance is consistent with cometary ices from Rosetta
Authors: Ligterink N. F. W. , Kama M.
Published: March 2018

Context. Cometary ices are formed during star and planet formation, and their molecular and elemental makeup can be related to the early solar system via the study of inter- and protostellar material. Aims. We set out to place the first observational constraints on the interstellar gas-phase abundance of bromine (Br). We further aim to compare the protostellar Br abundance with that measured by Rosetta in the ices of comet 67P/Churyumov–Gerasimenko.

Methods. Archival Herschel data of Orion KL, Sgr B2(N), and NGC 6334I are examined for the presence of HBr and HBr+ emission or absorption lines. A chemical network for modelling HBr in protostellar molecular gas is compiled to aid in the interpretation.

Results. HBr and HBr+ were not detected towards any of our targets. However, in the Orion KL Hot Core, our upper limit on HBr/H2O is a factor of ten below the ratio measured in comet 67P. This result is consistent with the chemical network prediction that HBr is not a dominant gas-phase Br carrier. Cometary HBr is likely predominantly formed in icy grain mantles which lock up nearly all elemental Br.
Fundamental parameters of massive stars in multiple systems: The cases of HD 17505A and HD 206267A
Authors: Raucq F. , Rauw G. , Mahy L. , Simón-Díaz S.
Published: March 2018

Context. Many massive stars are part of binary or higher multiplicity systems. The present work focusses on two higher multiplicity systems: HD 17505A and HD 206267A.

Aims. Determining the fundamental parameters of the components of the inner binary of these systems is mandatory to quantify the impact of binary or triple interactions on their evolution.

Methods. We analysed high-resolution optical spectra to determine new orbital solutions of the inner binary systems. After subtracting the spectrum of the tertiary component, a spectral disentangling code was applied to reconstruct the individual spectra of the primary and secondary. We then analysed these spectra with the non-LTE model atmosphere code CMFGEN to establish the stellar parameters and the CNO abundances of these stars.

Results. The inner binaries of these systems have eccentric orbits with e ~ 0.13 despite their relatively short orbital periods of 8.6 and 3.7 days for HD 17505Aa and HD 206267Aa, respectively. Slight modifications of the CNO abundances are found in both components of each system. The components of HD 17505Aa are both well inside their Roche lobe, whilst the primary of HD 206267Aa nearly fills its Roche lobe around periastron passage. Whilst the rotation of the primary of HD 206267Aa is in pseudo-synchronization with the orbital motion, the secondary displays a rotation rate that is higher.

Conclusions. The CNO abundances and properties of HD 17505Aa can be explained by single star evolutionary models accounting for the effects of rotation, suggesting that this system has not yet experienced binary interaction. The properties of HD 206267Aa suggest that some intermittent binary interaction might have taken place during periastron passages, but is apparently not operating anymore.
Analysis and numerical solver for excitatory-inhibitory networks with delay and refractory periods
Authors: Cáceres María J. , Schneider Ricarda
Published: March 2018

The network of noisy leaky integrate and fire (NNLIF) model is one of the simplest self-contained mean-field models considered to describe the behavior of neural networks. Even so, in studying its mathematical properties some simplifications are required [Cáceres and Perthame, J. Theor. Biol. 350 (2014) 81–89; Cáceres and Schneider, Kinet. Relat. Model. 10 (2017) 587–612; Cáceres, Carrillo and Perthame, J. Math. Neurosci. 1 (2011) 7] which disregard crucial phenomena. In this work we deal with the general NNLIF model without simplifications. It involves a network with two populations (excitatory and inhibitory), with transmission delays between the neurons and where the neurons remain in a refractory state for a certain time. In this paper we study the number of steady states in terms of the model parameters, the long time behaviour via the entropy method and Poincaré’s inequality, blow-up phenomena, and the importance of transmission delays between excitatory neurons to prevent blow-up and to give rise to synchronous solutions. Besides analytical results, we present a numerical solver, based on high order flux-splitting WENO schemes and an explicit third order TVD Runge-Kutta method, in order to describe the wide range of phenomena exhibited by the network: blow-up, asynchronous/synchronous solutions and instability/stability of the steady states. The solver also allows us to observe the time evolution of the firing rates, refractory states and the probability distributions of the excitatory and inhibitory populations.
Product environmental assessment as vector of differentiation – ACéVOIL, a new tool for the vegetable oil sector
Authors: Badey Laureen , Bosque Fabrice
Published: March 2018

Environmental impacts of human activities, heightened consumer concern over the food they eat, and business survival hinging on increasing performance mean there is pressure from all sides to reduce product environmental impacts—a strategic challenge to help keep businesses in business and improve competitiveness. Conscious of this challenge, the oilcrop commodity chain wanted to provide vegetable oil producers and users with a tool for assessing the environmental impacts of vegetable oil-based foods. The tool is called ACéVOIL, and can be used to validate the environmental value benefit of ecodesign initiatives as-deployed or as-designed. ACéVOIL accounts for every stage in the end-to-end commodity production and distribution process, making it possible to control and contain any pollution transfers between two distinct environmental impacts or two lifecycle stages. The tool also outputs results that can be readily communicated out to clients and/or consumers as part of a product information backbone to differentiate from competitor products and up-value the ecodesign initiatives implemented. However, communicating LCA results out to the general public can prove tricky business, so the exercise needs to be managed with care and forethought. Several upgrades are envisioned to extend the scope of ACéVOIL out to biomass-based products made from pure or processed vegetable oils.
Improved rapeseed oil extraction yield and qualityviacold separation of ethanol miscella
Authors: Citeau Morgane , Albe Slabi Sara , Joffre Florent , Carré Patrick
Published: March 2018

In the extraction of vegetable oils, the idea of using ethanol as a solvent, allowing solvent recycling without distillation, can be attested as early as 1948 (Beckel), yet it is now seldom envisaged. The development of organic farming and a growing demand for a more natural diet prompted us to revisit this approach, which takes advantage of the relatively low affinity of ethanol for lipids to produce pure crude oils and meal with higher protein content. This method is based on the change of oil solubility in ethanol with temperature. Rapeseed oil extraction was carried out by hot pressurized ethanol (subcritical extraction condition). Oil was then recovered by cooling the miscella and demixing of two phases, an oil-rich phase and a solvent-rich phase. This study, after verifying the kinetics of extraction, focused on the optimization of the demixing temperature based on the amount and quality of recovered oil. The results show that ethanol extraction followed by cold demixing of the miscella makes it possible to obtain a high quality oil, free of free fatty acids and phospholipids.
A novel robust multivariate regression approach to optimize multiple surfaces
Authors: Moslemi Amir , Seyyed-Esfahani Mirmehdi
Published: March 2018

Response surface methodology involves relationships between different variables, specifically experimental inputs as controllable factors, and a response or responses by incorporating uncontrollable factors named nuisance. In order to optimize these response surfaces, we should have accurate response models. A common approach to estimate a response surface is the ordinary least squares (OLS) method. Since OLS is very sensitive to outliers, some robust approaches have been discussed in the literature. Most problems face with more than one response which are mostly correlated, that are called multi-response problem. This paper presents a new approach which takes the benefits of robust multivariate regression to cope with the mentioned difficulties. After estimating accurate response surfaces, optimization phase should be applied in order to have proper combination of variables and optimum solutions. Global criterion method of multi-objective optimization has also been used to reach a compromise solution which improves all response variables simultaneously. Finally, the proposed approach is described analytically by a numerical example.
Bi-objective mean–variance method based on Chebyshev inequality bounds for multi-objective stochastic problems
Authors: Amoozad Mahdiraji Hannan , Razavi Hajiagha Seyed Hossein , Hashemi Shide Sadat , Zavadskas Edmundas Kazimieras
Published: March 2018

Multi-objective programming became more and more popular in real world decision making problems in recent decades. There is an underlying and fundamental uncertainty in almost all of these problems. Among different frameworks of dealing with uncertainty, probability and statistic-based schemes are well-known. In this paper, a method is developed to find some efficient solutions of a multi-objective stochastic programming problem. The method composed a process of transforming the stochastic multi-objective problem to a bi-objective equivalent using the concept of Chebyshev inequality bounds and then solving the obtained problem with a fuzzy set based approach. Application of the proposed method is examined on two numerical examples and the results are compared with different methods. These comparisons illustrated that the results are satisfying.
Schienenversorgung des Daumens – Optimal schienen
Authors: Bitzer Susanne
Published: March 2018

Bevor man rheumatisch erkrankte Patienten mit einer Schiene versorgt, gilt es herauszufinden, wann die Beschwerden auftreten: in Ruhe, bei bestimmten Tätigkeiten oder bei gewissen Handhaltungen. Für jede Gelegenheit stellt Susanne Bitzer mögliche Daumenschienen vor und empfiehlt, die Handrehabilitation mit einer guten Anleitung für Eigenübungen zu ergänzen.
Medikationsfehler – Lohnt sich ein automatisiertes Medikationssystem?
Authors: Blaich Cornelia
Published: March 2018

Risør BW et al. Cost-Effectiveness Analysis of an Automated Medication System Implemented in a Danish Hospital
Setting. Value Health 2017; 20: 886–893

Die Autoren untersuchen die Kosteneffektivität eines automatisierten Medikationssystems, das eine
elektronische Erfassung der Medikamentenverordnungen, ein automatisiertes Medikamenten-Dosiersystem und
eine Barcode-kontrollierte Verabreichung der Medikamente umfasst.
Effects of growth rate on structural property and adatom migration behaviors for growth of GaInNAs/GaAs (001) by molecular beam epitaxy
Authors: Li Jingling , Gao Peng , Zhang Shuguang , Wen Lei , Gao Fangliang , Li Guoqiang
Published: March 2018

We have investigated the structural properties and the growth mode of GaInNAs films prepared at different growth rates (Rg) by molecular beam epitaxy. The crystalline structure is studied by high resolution X-ray diffraction, and the evolution of GaInNAs film surface morphologies is studied by atomic force microscopy. It is found that both the crystallinity and the surface roughness are improved by increasing Rg, and the change in the growth mode is attributed to the adatom migration behaviors particularly for In atoms, which is verified by elemental analysis. In addition, we have presented some theoretical calculation results related to the N adsorption energy to show the unique N migration behavior, which is instructive to interpret the growth mechanism of GaInNAs films.