bluuebunny/crossref_metadata_2025 huggingface dataset:
OVERRIDING MANDATORY PROVISIONS IN CROATIAN PRIVATE INTERNATIONAL LAW
Authors: Zgrabljić Rotar Dora
Published: December 2021

Overriding mandatory provisions are mandatory provisions that are applicable in situations with an international element. The author analyses overriding mandatory norms in the European private international law and in the Croatian national private international law. The definition of such norms provided in the 2017 Croatian Private International Law Act is almost a verbatim copy of the definition provided in the Rome I Regulation on the law applicable to contractual obligations. The 1982 Croatian Private International Law Act did not provide for a definition of overriding mandatory norms but it was uniformly accepted in the scholarly interpretations that those types of mandatory norms were accepted by the Croatian private international law system. Moreover, the 1982 PIL Act included a substantive family law provision, which was, in essence, an overriding mandatory provision. However, Croatian courts and practitioners have been reluctant to refer explicitly to an applied norm as an overriding mandatory one. The reasons behind that might be that that the courts were better acquainted with the public policy exception, since public policy was explicitly mentioned in the 1982 PIL Act, as well as in some other legal acts. In addition, the legislator does not explicitly note that a provision is an overriding mandatory one in the provision itself, which leads to the outcome that the courts and other practitioners are burdened with a complex task of interpretation of a provision they think might be an overriding mandatory one. The author aims at providing guidelines to facilitate that task.
A relevância do trabalho do enfermeiro na gestão em saúde, na prevenção de agravos e controle de custos em uma operadora de saúde
Authors: Araújo Claudirene Milagres , Oliveira Felipe Fernandes de , Santos Jobelle Augusta Martins dos , Silva Lorena Batista , Dupim Patrícia Eliza Miranda , Ferreira Brisa Emanuelle Silva , Ávila David Mattos de Andrade , Monteiro Luciana Alves Silveira
Published: December 2021

Objetivo: Descrever a relevância do profissional enfermeiro em uma operadora de saúde, na gestão da prevenção de agravos e controle de custos através da telessaúde. Métodos: Trata-se de uma pesquisa exploratória, descritiva com abordagem qualitativa. O presente estudo foi realizado em uma operadora da rede suplementar de saúde, os dados foram coletados por meio de entrevistas, com 10 enfermeiros atuantes na telessaúde. Resultados: O estudo evidenciou o enfermeiro como profissional fundamental e responsável pela prevenção de agravos e redução de custos. Para os entrevistados o uso das tecnologias de informação aliadas ao conhecimento adquiridos sobre prevenção de agravos e promoção em saúde, gerou uma ferramenta onde o enfermeiro tem total autonomia para desenvolver atividades de sua competência e realizar o controle da carteira. Conclusão: Apesar das dificuldades por sua subvalorização, é possível perceber que o enfermeiro consegue se mostrar um gestor eficiente desenvolvendo ações modificadoras e permanentes que promovem saúde.
Nilai Pendidikan Karakter pada Tindak Tutur Ilukosi dalam Podcast Deddy Corbuzeir Bersama Syekh Ali Jaber
Authors: Rudi  , Joko Widodo
Published: December 2021

This study aims to describe the types of illocutionary speech and the value of character education in the speech on the video podcast of Deddy Corbuzier with Syekh Ali Jaber. This type of qualitative research with a descriptive approach. Sources of research data are utterances spoken by Deddy Corbuzier, Syekh Ali Jaber, and Gus Mifta in Deddy Corbuzier's Podcast video with Syekh Ali Jaber on Deddy Corbuzier youtube channel. The research data is in the form of sentences that reflect illocutionary speech acts and the value of character education. The data collection technique is done by using observation technique. The data analysis technique uses the Miles and Huberman model, which includes the stages of data reduction, data presentation, and conclusion/verification. The results showed: (1) types of illocutionary speech acts include assertive, directive, commissive, and expressive speech acts. (2) The value of character education includes the character of social care, religion, honesty, tolerance, love for the country, creativity, democracy, and love peace. Based on the findings, the dominant character education value in the speech activity is the value of religious character. This can happen, because it is influenced by the background of the speaker and the context of the speech.
Solvent Remodeling in Single-Chain Amphiphilic Heteropolymer Systems
Authors: Hilburg Shayna , Alexander-Katz Alfredo
Published: December 2021

Through molecular dynamics simulations, we demonstrate how single-chain nanoparticles (SCNPs) assembled via transient linkages in water can remodel in organic solvent. Methacrylate-based random heteropolymers (RHPs) have shown promise in an assortment of applications that harness their bio-inspired properties. While their molecular behavior has been broadly characterized in water, many newer applications include the use of organic solvent rather than bio-mimetic conditions in which the polymer assemblies, typically driven by the hydrophobic effect, are less well understood. Here, we examine a specific RHP system which forms compact globular morphologies in highly polar and non-polar environments while adopting extended conformations in solvents of intermediate polarity. We also demonstrate the pivotal role of electrostatic interactions between charge groups in low dielectric mediums. Finally, we compare high temperature anneal cycles to room temperature equilibrations to illuminate activation barriers to remodeling upon environmental changes.
Substituent Control of σ-interference Effects in the Transmission of Saturated Molecules
Authors: Garner Marc H. , Koerstz Mads , Jensen Jan H. , Solomon Gemma C.
Published: December 2021

The single-molecule conductance of saturated molecules can potentially be fully suppressed by destructive quantum interference in their σ-system. However, only few molecules with σ-interference have been identified and the structure-property relationship remains to be elucidated. Here, we explore the role of substituents in modulating the electronic transmission of saturated molecules. In functionalized bicyclo[2.2.2]octanes, the transmission is suppressed by σ- interference when fluorine substituents are applied. For bicyclo[2.2.2]octasilane and - octagermanes the transmission is suppressed when carbon-based substituents are used, and such molecules are likely to be highly insulating. For the carbon-based substituents we find a strong correlation between the appropriate Hammett constants and the transmission. The substituent effect enables systematic optimization of the insulating properties of saturated molecular cores.
Unsymmetrical Growth Synthesis of Nontraditional Dendrimers
Authors: Ding Shengtao , Niu Lijiao , Zhang Xueyan
Published: December 2021

Developing highly complex molecules is of great significance in science and technology. Here we present an unprecedented type of dendrimer assembled from linear ABB-type monomer. The construction of this nontraditional ramified architecture was facilely achieved through one simple convergent strategy established on the iridium-catalyzed cycloaddition of organic azides with internal 1-thioalkynes (IrAAC). By virtue of the unsymmetrically growing fashion in this process, diverse functional groups could be conveniently distributed on both of its exterior and interior layers. Syntheses of two dendrons from the cooperation of one linear alkyne motif with different azides were presented to demonstrate the efficiency and fidelity of this protocol. Post-modifications on their core or periphery were further conducted, resulting in diverse newly functionalized dendrimers with up to ~16.0 kDa molecular weight. The identity and purity of these unsymmetrical dendritic macromolecules were well confirmed by 1H NMR, MS and SEC analysis.
Multiscale Models in Heterogeneous Catalysis: Incorporating Dynamics into Reaction Kinetics
Authors: Omojola Toyin
Published: December 2021

Modern operando spectroscopy and microscopy, and kinetic investigations have provided qualitative evidence for active site dynamics, catalyst surface dynamics, and charge transport. On the macroscale, intraparticle and interparticle mass and heat transfer can be tuned to optimise selectivity over heterogeneous catalysts. On the microscale, adsorbate-induced restructuring, adsorbate mobility, surface composition, oxidation states, charge transport, bandgap, and the degree of coordination of the active site have been identified for controlling product selectivity. There exist, however, limited physics-based and data-driven multiscale models that can assimilate these qualitative descriptors in an integrated manner to extract quantitative catalyst activity, stability, and product selectivity descriptors. A multiscale model, which describes the evolution of gas species, adspecie accumulation due to reactivity, stability, lifetime, and mobility, charge transport involving electrons and holes, heat transfer for non-isothermal conditions due to reaction exothermicity, and the changing catalyst states is provided. Dynamical effects are included in these models to bridge the gap between laboratory-scale studies and industrial technical reactors.
Iodine-mediated electrocatalysis assist Annulation/cyclization via Intramolecular Benzylic C–H Amination: Batch vs Flow Electrochemistry
Authors: Ahmed Nisar , Martins Guilherme. M.
Published: December 2021

The access of heterocyclic compounds via direct amination of C-H bonds are of vital interest because of their role in pharmaceutical and natural products. The combination of molecular iodine and electricity activates benzylic C-H bond and facilitates the amination process via intramolecular C-N bond formation. Iodine works as a mediator for the formation of C-N bond via activation of a distance C-H bond through intermediate N-I bond under electrochemical conditions, so iodine can be called electrocatalyst. Under both batch & flow electrochemistry conditions, similar results were obtained in cyclization product with 77 & 78% yields respectively. However, in case of annulation reaction higher yield was obtained with 99% conversion under flow electrochemical conditions using our design of home-made flow microreactor. In both electrochemical transformations, cyclization as well as annulation reaction, no photocatalyst was used. Notably, flow reactions work under safe & environmentally friendly conditions, and continuous products are obtained.
Entanglement of Square Nets in Covalent Organic Frameworks
Authors: Jin Fangying , Nguyen Lac Ha , Zhong Zhiye , Han Xing , Zhu Chenhui , Pei Xiaokun , Ma Yanhang , Yaghi Omar
Published: December 2021

Two entangled 2D square COFs have been synthesized from 4,4',4'',4'''-(9,9'-spirobi[fluorene]-2,2',7,7'-tetrayl)-tetrabenzaldehhyde (SFTB) and p-phenylenediamine (PPA) and benzidine (BZD) to form COF-38, [(SFTB)(PPA)2]imine and its isoreticular form COF-39, [(SFTB)(BZD)2]imine. We also report the single crystal electron diffraction structure of COF-39 and find that it is composed of mutually entangled 2D square nets (sql). These COFs represent the first examples of entangled 2D COF structures, which as we illustrate were made possible by our strategy of using the distorted tetrahedral SFTB building unit. SFTB overcomes the propencity of 2D COFs to stack through π-π stacking and allows for entanglements to form. This work adds significantly to the design principles of COFs.
Integrating Synthetic Accessibility with AI-based Generative Drug Design
Authors: Parrot Maud , Tajmouati Hamza , Barros Ribeiro da Silva Vinicius , Ross Atwood Brian , Fourcade Robin , Gasthon-Mathé Yann , Do Huu Nicolas , Perron Quentin
Published: December 2021

Generative models are frequently used for de novo design in drug discovery projects to propose new molecules. However, the question of whether or not the generated molecules can be synthesized is not systematically taken into account during generation, even though being able to synthesize the generated molecules is a fundamental requirement for such methods to be useful in practice. Methods have been developed to estimate molecule synthesizability, but, so far, there is no consensus on whether or not a molecule is synthesizable. In this paper we introduce the Retro-Score (RScore), which computes a synthetic feasibility score of molecules by performing a full retrosynthetic analysis through our data-driven synthetic planning software Spaya, and its dedicated API: Spaya-API (https://spaya.ai). After a comparison of RScore with other synthetic scores from the literature, we describe a pipeline to generate molecules that validate a list of targets while still being easy to synthesize. We further this idea by performing experiments comparing molecular generator outputs across a range of constraints and conditions. We show that the RScore can be learned by a Neural Network, which leads to a new score: RSPred. We demonstrate that using the RScore or RSPred as a constraint during molecular generation enables to obtain more synthesizable solutions, with higher diversity. The open-source Python code containing all the scores and the experiments can be found on https://github.com/iktos/generation-under-synthetic- constraint.
Combinatorial library screening of quinadoline B derivatives against SARS-CoV-2 RNA-dependent RNA polymerase
Authors: brogi simone , Quimque Mark Tristan , Notarte Kin Israel , Africa Jeremiah Gabriel , Hernandez Jenina Beatriz , Tan Sophia Morgan , Calderone Vincenzo , Macabeo Allan Patrick
Published: December 2021

The unprecedented global health threat of SARS-CoV-2 has sparked a continued interest to discover novel anti-COVID-19 agents. To this end, we present here a computer-based protocol for identifying potential compounds targeting RNA-dependent RNA polymerase (RdRp). Starting from our previous study in which, by a virtual screening campaign, we identified a fumiquinazolinone alkaloid quinadoline B (Q3), an antiviral fungal metabolite with significant activity against SARS-CoV-2 RdRp, we applied an in silico combinatorial methodologies for generating and screening a library of anti-SARS-CoV-2 candidates with strong in silico affinity for RdRp. For this study, the quinadoline pharmacophore was subjected to structural iteration obtaining a Q3-focused library of over 900,000 unique structures. This chemical library was explored to identify binders of RdRp with greater affinity with respect to the starting compound Q3. Coupling this approach with the evaluation of physchem profile, we found 26 compounds with significant affinities for the RdRp binding site. Moreover, top-ranked compounds were submitted to molecular dynamics to evaluate the stability of the systems during a selected time, and for deeply investigating the binding mode of the most promising derivatives. Among the generated structures, five compounds, obtained by inserting nucleotide-like scaffolds (1, 2, and 5), heterocyclic thiazolyl benzamide moiety (compound 3), and a peptide residue (compound 4), exhibited enhanced binding affinity for SARS-CoV-2 RdRp, deserving further investigation as possible antiviral agents. Remarkably, the presented in silico procedure provides a useful computational procedure for hit-to-lead optimization, having implications in anti-SARS-CoV-2 drug discovery and in general in the drug optimization process.
Accelerating Net Zero from the perspective of Optimizing a Carbon Capture and Utilization System
Authors: Hao Zhimian , Barecka Magda , Lapkin Alexei
Published: December 2021

Net zero requires an accelerated transition from fossil fuels to renewables. Carbon capture and utilization (CCU) can be an effective intermediate solution for the decarbonization of fossil fuels. However, many research works contain renewables in the design of CCU systems, which may mislead stakeholders regarding the hotspots of CCU systems. In this work we build a model of a CCU system with no renewables involved, and evaluate its greenhouse (GHG) emissions based on the life cycle assessment with a cradle-to-gate boundary. To pursue the best system performance, an optimization framework is established to digitalize and optimize the CCU system regarding GHG emissions reduction. The optimized CCU can reduce GHG emissions by 13% compared with the conventional process. Heating is identified as the most significant contributor to GHG emissions, accounting for 60%. Electrifying heating fully by low-carbon electricity can further reduce GHG emissions by 47%, but such extreme conditions will significantly sacrifice the economic benefit. By contrast, the multi-objective optimization can show how the decisions can affect the balance between GHG emissions and profit. Further, this work discusses the dual effect of carbon pricing on the CCU system – raising the cost of raw materials and utilities, but also gaining credits when emissions are reduced in producing valued products.
A comprehensive evaluation of the potential binding poses of fentanyl and its analogs at the µ-opioid receptor
Authors: Xie Bing , Goldberg Alexander , Shi Lei
Published: December 2021

Fentanyl and its analogs are selective agonists of the µ-opioid receptor (MOR). Among novel synthetic opioids (NSOs), they dominate the recreational drug market and are the main culprits for the opioid crisis, which has been exacerbated by the COVID-19 pandemic. By taking advantage of the crystal structures of the MOR, several groups have investigated the binding mechanism of fentanyl, but have not reached a consensus, in terms of both the binding orientation and the fentanyl conformation. Thus, the binding mechanism of fentanyl at the MOR remains an unsolved and challenging question. Here, we carried out a systematic computational study to investigate the preferred fentanyl conformations, and how these conformations are being accommodated in the MOR binding pocket. We characterized the free energy landscape of fentanyl conformations with metadynamics simulations, as well as performed long-timescale molecular dynamics simulations to compare and evaluate several possible fentanyl binding conditions. Our results indicate that the most preferred binding pose in the MOR binding pocket corresponds well with the minima on the energy landscape of fentanyl in the absence of the receptor, while the energy landscape can be reconfigured by modifying the fentanyl scaffold. The interactions with the receptor may stabilize a slightly unfavored fentanyl conformation in an alternative binding pose. By extending similar investigations to fentanyl analogs, our findings establish a structure-activity relationship of fentanyl binding at the MOR. In addition to providing a structural basis to understand the potential toxicity of the emerging NSOs, such insights will contribute to developing new, safer analgesics.
Imagen corporal, calidad de vida y control percibido en pacientes con cáncer colorrectal: una revisión
Authors: Senabre Pedro , Philips María-Cecilia
Published: December 2021

El presente artículo tiene como propósito llevar a cabo una revisión acerca de la relación entre el cáncer colorrectal y tres variables psicológicas: la imagen corporal, la calidad de vida y el control percibido. El diagnóstico de una enfermedad crónica es siempre una fuente de estrés que puede desembocar en una pérdida de control, ansiedad, sentimiento de incapacidad y que requiere adaptación por parte del paciente. La revisión teórica se realizó en diferentes bases de datos: EBSCO, PubMed, Medline, Google Académico y libros especializados en este tema. Como conclusión, podemos decir que las dos primeras variables se encuentran estrechamente relacionadas; es decir, personas que padecen este tipo de cáncer presentan peor imagen corporal y una inferior calidad de vida. Finalmente, proponemos que se lleve a cabo una revisión más profunda acerca de este tema, especialmente en la tercera variable: control percibido.
El tema del doble en Manuel Mejía Valera y José Durand
Authors: Vega Mendieta Nehemías
Published: December 2021

El presente artículo analizará el tema del doble o doppelgänger en dos narradores peruanos de la Generación del 50: Manuel Mejía Valera y José Durand. Dentro de la narrativa de esta generación, se desarrolló una vertiente fantástica, la cual fue casi ignorada por la crítica hasta inicios del presente siglo. Uno de los tópicos recurrentes dentro de esta vertiente fue el tema del doble, el cual hace referencia a los conceptos de identidad y otredad, que se pueden ligar a los cambios sociales que se realizaron en dicha década. Manuel Mejía Valera y José Durand tuvieron una breve producción cuentística con cierta inclinación hacia lo fantástico y en el que el tema del doble fue tratado de manera peculiar para abordar el problema de la identidad y la relación con los otros.
Globalización y el diálogo de saberes, en universidades interculturales del Perú
Authors: Bada Laura Wendy Nelly , Wisum Petsa Ulises
Published: December 2021

Transversalizar la interculturalidad en los documentos de gestión, en las universidades interculturales, es un desafío organizativo, académico y político, porque es responder a los diferentes contextos de los pueblos originarios andinos amazónicos, en esa perspectiva es importante determinar si existe relación entre la globalización de la educación y el diálogo de saberes, en la estructura del enfoque intercultural. La investigación responder al enfoque cuantitativo, la metodología fue correlacional causal, la muestra fueron los documentos de gestión de las cuatro universidades interculturales del Perú, el nivel de significancia del 5%, se utilizó la prueba de análisis correlacional de Pearson, se obtuvo según la prueba de hipótesis el -0.969 siendo una correlación indirecta entre las dos variables.
Estrategias para el desarrollo de habilidades sociales en estudiantes de la Institución Educativa de Santillana, 2020
Authors: Aucasi Tenorio Gladys Marianela
Published: December 2021

Esta investigación se realizó para determinar la influencia de las estrategias lúdicas para desarrollar las habilidades sociales en estudiantes quechuahablantes de la Institución Educativa de Santillana, 2020. De corte cuantitativo, de tipo experimental, mediante el diseño preexperimental. Participaron como muestra 17 estudiantes, a través del instrumento escala de apreciación sobre habilidades sociales, cuyos resultados fueron procesados mediante la prueba estadística Wilcoxon. Las evidencias estadísticas muestran que el nivel de significancia es igual a 0,000, que es menor a 0,05; por lo que, se concluye que las estrategias lúdicas influyen significativamente en el desarrollo de las habilidades sociales en estudiantes quechuahablantes de la Institución Educativa de Santillana, 2020.
Programa de coaching para disminuir el síndrome de burnout en trabajadores de la Universidad Nacional del Centro del Perú
Authors: Veli Chuquillanqui Rocío , Huachos Pacheco Aníbal
Published: December 2021

Iniciamos la investigación preguntándonos ¿En qué medida un programa de coaching disminuirá el nivel de síndrome de Burnout que tienen los trabajadores de la Universidad Nacional del Centro del Perú?, el propósito de la investigación es determinar como el coaching disminuye el nivel de Burnout que presentan los trabajadores de la institución mencionada. Investigación básica, de tipo explicativa con un diseño preexperimental, la muestra es no probabilística de tipo sujetos voluntarios integrada por 50 trabajadores, se utilizó como instrumento de investigación el inventario de Maslach, se utilizó la estadística descriptiva e inferencial; se determinó que el coaching disminuye el nivel de Burnout que tienen los trabajadores de la Universidad nacional del Centro del Perú, donde se encontró una media de 72 que representa un nivel elevado y después del programa una media de 56,5 que representa un nivel bajo; lo que es remarcado con una tc=6,5876 frente a una t0,05=1,667.
Análisis inferencial del consumo de bienes y servicios culturales de estudiantes de Medicina
Authors: Nodals García Carlos Lázaro
Published: December 2021

Fundamento: es necesario conocer la significación del consumo de bienes y servicios culturales en estudiantes de Medicina. Objetivo: Analizar el consumo de bienes y servicios culturales en estudiantes de Medicina. Métodos: Se aplicaron métodos teóricos, etnográfico, análisis de contenido, teoría fundamentada y análisis de actos del habla.  Técnicas de análisis documental, observaciones, encuestas, entrevistas y grupos de discusión. Resultados: la industria cultural homogeniza valores, penetra lo afectivo, cognitivo y simbólico. Los audiovisuales viabilizan nuevos procedimientos cognitivos, lenguajes y grupos sociales. Conclusiones: El consumo de bienes y servicios culturales complejiza la formación de un médico crítico, reflexivo, solidario y culto.
ACCESSIBILITY EVALUATION OF THE TRANSIT PLAZA OF TANAH ABANG STATION ACCORDING TO USERS WITH VISUAL IMPAIRMENT
Authors: Bonita Tamara , L. Lukman Aldyfra
Published: December 2021

Abstract - Visual impairment is a term given to someone who does not have healthy vision. To fulfill their daily life needs, people with visual impairment tend to depend on the facilities in public open spaces. Accessibility that should support people with visual impairment in using public transportation facilities is often poorly maintained. This kind of condition could lead to fatal consequences to the safety of persons with disabilities. Options linked  to accessing public open spaces for people with visual impairment become limited due to the lack of facilities. The refurbishment has been done at Tanah Abang Station by providing a transit plaza for users that is connected to various public transportation facilities, which enables easy and comfortable navigation. This has become an opportunity, to build better public facilities that are accessible to all users, including for people with visual impairment. Through this effort, the transit plaza should be able to serve as a public space that is beneficial for people with visual impairment, so there are more possibilities to ensure their quality of life. The purpose of this study is to determine the extent to which the transit plaza can provide accessibility for people with visual impairment. The method used is qualitative and data collection was carried out through literature studies, field surveys as well as interviews and simulations with people with visual impairment. The results conclude that the accessibility value referring to technical requirements indicates that the transit plaza sufficiently complies with accessibility standards regarding public open spaces. This value is compared to the experience of people with visual impairment . This study  found that there are some differences from the aspect of convenience according to the people with visual impairment's point of view. The mobility in the transit plaza is considered easy and safe by people with visual impairment. When they had to determine  direction or orientation, people with visual impairment who were not familiar with transit plaza still had  difficulties to navigate independently. When facing these situations, blind people adapted by relying on abilities other than their sight as an alternative. Transit plaza could provide universal convenience for users by accommodate accessibility that can not only encourage the independence of the people with visual impairment, but also support comfort and safety of  individuals without visual impairment.

 

Keywords: Visual impairment, accessibility, transit plaza
PHYSICAL-SPATIAL ASPECT IN LOCAL EXPRESSION OF TOWNSCAPE ON SAMIRONO YOGYAKARTA
Authors: Devin Setiawan Leonardo , Budiwidodo Pangarso Fransiskus Xaverius
Published: December 2021

Abstract - Cities change by time to time physically and non-physically. The city development produces a distinctive character even in the smallest urban creature. This distinctive character does not take quickly but is slowly and full of challenges.

Townscape is a visual impression of buildings arrangement, roads, and spaces those are expressed organically to form urban spaces. Therefore, a townscape that exists in an urban area is created on delevlopment or grows by unintentionally. Apart from that, the character of a townscape from one place is different from the other. The townscapes had been created and specific in each place.

The literatures for this research are: 'The Concise Townscape', 'The Aesthetic Townscape', and 'Road Form and Townscape'. The three literatures describe the existence of townscape in Europe and Japan. This is the basic knowledge in townscape and how it is applied in Indonesia, especially in the city of Yogyakarta. The urban space chosen in this research is Padukuhan Samirono.

Padukuhan Samirono is located in the north of Yogyakarta City and is very close to Gadjah Mada University and Negri Yogyakarta University. Padukuhan Samirono is known as an area that provides student accomodation. The community still stand fot maintaining their cultural habit such as gathering, cultural performances, and parades.

This study examines the Townscape in Padukuhan Samirono. The social and cultural activities expressed their locality as seen as in its townscape. The pictorial analysis method identify the elements of townscapes wich effects the urban space. By describing the elements of urban space with 7 factors: nature elements, space organization, mass, proportion, activity, carving, and streetscape, the local expression criteria of Padukuhan Samirono’s can be formulated.

Based on observations, the local expression of townscape on Samirono changes into a modern form. This research attempts to enhance people’s aprrectiation about townscape, especially townscape in Indonesia.

 

Key Words: townscape, pictorial analysis, Samirono, Javanese, locality
CINEMATIC SPACE STUDIES OF KOMPLEK SUSTER-SUSTER ST. FRANSISKUS IN SEMARANG
Authors: Anandisya Nadira , S. Wijayaputri Caecilia
Published: December 2021

Abstract - Cinema and Architecture are two art media that dependent on some human senses to give experience and define space compared of other art medium. These two media have been trying to show and convince film viewers or architecture users as a work of art. Both have quality value that will be higher if they can be as close to reality.

However, architecture tend to use visual but lack of emotions. As a result, buildings left us as only a viewers without invite us to engaged. Therefore, from cinema to architecture, the thinking of thematic conditions of architecture can be brought together with conceptual, contextual, architectonic, and technical.

 Ave Maryam (2020) is a film that takes place in Semarang, and Kompleks Susteran St. Fransiskus is the main setting that interesting to studied. From each scene it can clearly describe space with a visual composition to convey a strong spatial experience. Departing from an approach to cinema that is parallel to architecture so that the audience can experience spaces outside the formal architectural experience.

The purpose of this study is to identify cinematic themes that can be discussed and reconstruct the cinematic space as a search for understanding the potential and meaning of cinematic in Kompleks Kesusteran St. Fransiskus based on the film Ave Maryam (2020). By using a qualitative descriptive method, from data that achieved by literature studies and film observations. It can be concluded that the existing approaches to architecture and cinema from Ave Maryam (2020) can be interpreted to build a concept that achieves the beauty and experience experienced in architecture such as watching the film.

 

Key Words: cinematic, architecture and film, cinematic approach, Ave Maryam, Komplek Kesusteran St. Fransiskus, Semarang.
Síntesis de evidencia y recomendaciones: guía de práctica clínica para el manejo de la retinopatía de la prematuridad
Authors: Organización Panamericana de la Salud
Published: December 2021

Introducción.

La retinopatía del prematuro (ROP) es una enfermedad prevenible potencialmente grave que se puede presentar en hasta el 34% de los recién nacidos de pretérmino. La Organización Mundial de la Salud incluye el manejo de esta entidad dentro de sus políticas prioritarias para reducir la prevalencia de ceguera prevenible.

Objetivos.

Sintetizar las recomendaciones incluidas en la Guía de práctica clínica para el manejo de la retinopatía de la prematuridad, publicada por la Organización Panamericana de la Salud, con el fin de presentar recomendaciones para la prevención, diagnóstico, tratamiento y seguimiento de recién nacidos con retinopatía del prematuro.

Métodos.

Se llevó a cabo una síntesis de la guía y sus recomendaciones. Además, se realizó una búsqueda sistemática en Pubmed, Lilacs, Health Systems Evidence, Epistemonikos y literatura gris de estudios desarrollados en la Región de las Américas con el fin de identificar barreras, facilitadores y estrategias de implementación.

Resultados.

Se formularon 30 recomendaciones y 14 puntos de buena práctica que aplican a los recién nacidos prematuros menores de 32 semanas de edad gestacional y/o menos de 1500 g de peso al nacer que hayan requerido oxígeno o presenten otros factores de riesgo para presentar ROP. Se identificaron barreras de acceso relacionadas con la disponibilidad de recurso humano, insumos y conocimiento de la guía para la implementación de las recomendaciones.

Conclusiones.

Las recomendaciones formuladas buscan proveer estrategias para la prevención, el diagnóstico y el tratamiento de ROP para los recién nacidos prematuros en América Latina y el Caribe, así como consideraciones para su implementación.
Síntesis de evidencia: directrices de práctica clínica basadas en la evidencia para el seguimiento de recién nacidos en riesgo
Authors: Organización Panamericana de la Salud
Published: December 2021

Introducción.

La Organización Mundial de la Salud recomienda focalizar la atención en el período neonatal, eliminar la mortalidad de causa prevenible y brindar cuidados de calidad. Es esencial conocer cuáles son las condiciones con alta probabilidad de ocurrencia en esa población para monitorearlos de forma sistemática, de modo que se logre su detección temprana; y el abordaje terapéutico y rehabilitación oportunos.

Objetivos.

Sintetizar las recomendaciones incluidas en lasDirectrices de práctica clínica basadas en la evidencia para el seguimiento de recién nacidos en riesgo, publicada por la Centro Latinoamericano de Perinatología/ Salud de la Mujer y Reproductiva de la Organización Panamericana de la Salud en el 2020, con el fin de presentar las estrategias para el seguimiento de los niños recién nacidos con condiciones de riesgo desde su nacimiento hasta los 2 años.

Métodos.

Se llevó a cabo una síntesis de la guía y sus recomendaciones. Además, se realizó una búsqueda sistemática en Pubmed, Lilacs, Health Systems Evidence, Epistemonikos y literatura gris de estudios desarrollados en la Región de las Américas, con el fin de identificar barreras, facilitadores y estrategias de implementación.

Resultados.

Se formularon 21 recomendaciones y 14 puntos de buena práctica que aplican a los recién nacidos con condiciones de riesgo hasta los dos años (prematuros y aquellos con alteraciones adquiridas o congénitas). Se identificaron barreras como la disponibilidad de pruebas de tamización, deficiencias en elsistema de referencia y conocimiento de las recomendaciones para su implementación.

Conclusiones.

La guía brinda recomendaciones sobre los criterios de egreso, incluidas pruebas de tamizaje; información y apoyo para padres y cuidadores; tamizaje y frecuencia de seguimiento de los niños en riesgo hasta los dos años en la Región de las Américas.
Respuesta con enfoque de derechos de la niñez frente a la pandemia por COVID-19 en Chile, Colombia y Perú
Authors: González Fernando , Pinzón-Segura María Camila , Pineda-Restrepo Bertha Luz , Carmen Calle-Dávila María del , Siles Valenzuela Estefanía , Herrera-Olano Natalia , Mesa Rubio María Lucía
Published: December 2021

Objetivo.

Describir las estrategias que fueron establecidas por Chile, Colombia y Perú durante el primer añode la pandemia por COVID-19 y compararlas desde el enfoque de derechos de la niñez.

Métodos.

Se realizó un estudio cualitativo de análisis comparado de políticas públicas, tomando com eje siete categorías construidas por el Capítulo Latinoamericano de laInternational-Society-for-Social- Pediatrics-and-Child-Healtha partir de la Convención de Derechos de la Niñez (CDN). La selecciónde los documentos de los países se realizó por conveniencia y su análisis en diálogos deliberativos.

Resultados.

Se revisaron 173 documentos de los tres países. Destaca como convergencia la priorización de la prevención de la transmisión comunitaria del virus, por sobre la promoción del ejercicio de derechos dela niñez, la falta de participación de niños, niñas y adolescentes (NNA) en el proceso de elaboración de las políticas públicas, y la falta de avance en el reconocimiento y protección del ejercicio de todos sus derechos. No hubo mayores divergencias más allá de brechas de desigualdad identificadas con base a la realidad de cada país.

Conclusión.

La pandemia ha afectado el funcionamiento de los sistemas económicos, sociales, de salud, educación, medioambiente y gobernanza de estos tres países. Si bien este estudio muestra un avance en la inclusión del enfoque de derechos de NNA en las políticas formuladas, su comprensión como sujetos sociales y políticos titulares de derecho podría permitir la construcción de alternativas colectivas que garanticen la salud y el bienestar para todas las personas en el curso de vida.
Research challenges and opportunities in the Caribbean area: first bibliometric study in the French West Indies, from 1989 to 2018
Authors: Contaret Cédric , Cesaire Raymond , Deloumeaux Jacqueline , Neviere Rémi , Resiere Dabor , Cabie André , Sylvestre Emmanuelle , Joachim Clarisse , Drame Moustapha
Published: December 2021

Objective.

To analyze, describe, and quantify the collaborations and scientific output of the two university teaching hospitals of Martinique and Guadeloupe, at the regional, national, and international level.

Methods.

A bibliometrics analysis was performed from the international databases Web of Science and PubMed, for the period from 1989 to 2018, inclusive (30 years). Three types of bibliometric indicators were used, namely quantitative indicators, performance indicators, and organization-specific indicators. Affiliations of the first and last authors were identified from PubMed.

Results.

Between 1989 and 2018, a total of 1 522 indexed articles were published with at least one author affiliated to either the University Hospital of Martinique (n = 827) or the University Hospital of Guadeloupe (n = 685). The majority of articles were in category Q1 (35.8% for Martinique and 35.2% for Guadeloupe). In Martinique, over the last 30 years, the three main research areas have been clinical neurology, ophthalmology, and surgery, together representing 28.7% of all research areas, with the highest number of articles published in the field of clinical neurology (n = 81). In the University Hospital of Guadeloupe, the area of hematology was largely represented, with 79 articles published. For both hospitals, the first and last authors of the article published were mainly from mainland France

Conclusions.

This quantitative analysis shows the development of medical and scientific research in Martinique and Guadeloupe over the last three decades, as well as the extent of their collaborative partnerships at the national and international levels.
Nudos críticos en la comprensión ontológica de la educación inclusiva
Authors: Ocampo González Aldo
Published: December 2021

A educação inclusiva não define claramente uma nova condição de humanidade, analisa preocupações de ordem contingente vinculadas a processos ideológicos, discursivos e relações de poder que participam da configuração do poder da condição de ser humano, fabricando novos códigos de legibilidade. O objetivo deste trabalho é analisar a matriz de produção ontológica da educação inclusiva e suas repercussões materiais e subjetivas na vida escolar. O método utilizado utiliza a pesquisa documental crítica. Entre suas principais conclusões estão: a) a construção de uma pragmática epistemológica micropolítica eb) a criação de uma concepção ontológica neo-materialista que privilegia a multiplicidade de modos de existência do ser humano.
Arquivos Digitais: possibilidades de pesquisa no campo da História da Educação
Authors: Silva dos Santos Daise
Published: December 2021

Discutir os usos dos Arquivos Digitais nas pesquisas em História da Educação é o objetivo do presente trabalho. Diante do cenário de pandemia de Sars-Cov-2, no qual os pesquisadores ficaram impossibilitados de consultar presencialmente os arquivos, o acesso às fontes de pesquisa tem sido possibilitado através de documentos digitais disponibilizados por alguns arquivos. A digitalização de materiais, bem como a realização de pesquisas com esses, já vinham sendo cada vez mais frequente no campo História da Educação, por conta facilidade de acesso e como modo de preservação de documentos originais. Contudo, como alguns pesquisadores têm apontado, os usos de recursos digitais nas pesquisas exigem cuidados metodológicos específicos que tem sido muita vezes negligenciados. Neste trabalho, busco apresentar alguns arquivos aos quais recorri para realização das minhas pesquisas e as discussões sobre o uso dos recursos digitais na História da Educação.
Influence of Capital Structure on Corporate Performance of Listed Firm in PSX: Role of External Factors
Authors: Hameed Abdul , Hussain Farheen Zahra , Naheed Khawar , Shahid Muhammad Sadiq
Published: December 2021

Purpose: A company’s capital structure is a blend of its equity and debt financing and is considered a significant factor in the valuation of any firm. The decisions related to capital structure formation play an integral role for the firms, therefore; this research tends to explore the factors of capital structure and their impact on firm performance. For this purpose, financial data for different listed companies in PSX has been gathered, and dividends and taxes are used as firm external factors.  Design/Methodology/Approach: To examine the impact, the panel data has been used for the period 2016-2020 and panel least square has been applied. Findings: The findings suggest that among the variables current ratio, dividends, taxation, total debt to total equity ratio, and the firm size are statistically significant to profitability. The study also concludes that dividends and tax have a greater impact on capital structure and firm performance.   Implications/Originality/Value: Managers and owners of the firms must make sure that their profits are used for future investments rather than payment of debts to avoid bankruptcy.
النوع كمتغير معدل للعلاقة بين الانتماء للوطن والتماسك والتكيف الأسري والمرونة العقلية
Authors: El Sayed El Keshky Mogeda
Published: December 2021

هدفت الدراسة إلى التحقق من العلاقات بين كل من الانتماء للوطن، والتماسك والتكيف الأسري، والمرونة العقلية، بالإضافة إلى فحص تأثير النوع كمتغير معدل لهذه العلاقات. وقد تمت دعوة المشاركين عبر البريد الإلكتروني والفيس بوك والواتس أب للمشاركة في الدراسة، وتكونت عينة الدراسة من عينة مقطعية من (1716) من السعوديين بمتوسط عمري 29.2 وانحراف معياري قدره 10.33 سنة، طُبق عليهم ثلاثة مقاييس هي مقياس المرونة العقلية، ومقياس التكيف والتماسك الأسري، ومقياس الانتماء للوطن. وتم استخدام تحليل المسار للتعرف على العلاقات بين المتغيرات، وللتحقق من دور النوع كمتغير مُعدل للعلاقة بين المتغيرات.
وتوصلت النتائج إلى وجود فروق جوهرية بين الذكور والإناث لصالح الإناث في كل من المرونة العقلية والتماسك الأسري، في حين كانت الفروق لصالح الذكور في التكيف الأسري. كما توصلت إلى وجود علاقة ارتباطية موجبة بين الانتماء للوطن والمرونة العقلية، وتنبؤ التماسك الأسري بالمرونة العقلية، ووٌجد تأثير مُعتدل للنوع على العلاقات بين المتغيرات. وأوصت الدراسة بضرورة مراعاة النوع الاجتماعي في تدخلات تعزيز كل من التماسك والتكيف الأسري، والانتماء للوطن والمرونة العقلية.
المسائل العارضة الجنائية في القانون المصري: دراسة مقارنة بالقانون الفرنسي
Authors: Abdul Hamid Mekki Mohamed
Published: December 2021

تناول هذا البحث دراسة المسائل العارضة الجنائية، وهي المسائل التي تعرض على القاضي أثناء نظر الدعوى الجنائية، ويتوقف عليها الفصل في هذه الدعوى، ويتعين على القاضي أن يوقف هذه الدعوى حتى تحسم المحكمة المختصة في هذه المسائل. وأن الفصل في هذه المسائل ضروري للسير في الدعوى؛ لأنها تتصل بركن من أركان الجريمة المرفوعة بها، وأن يكون الدفع بها جديًا، وأن يثيره المتهم. كما كشفت الدراسة أن المحاكم الفرنسية لا توقف الدعوى العمومية إذا ما أثيرت أمامها مسألة عارضة يتوقف عليها الفصل في هذه الدعوى، إلا في حالات محددة تعترض الدعوى أمام محكمة الجنح فقط، فالأصل هناك الأخذ بمبدأ اختصاص القاضي، على عكس القانون المصري. كما تطرقت الدراسة الى أن المشرع المصري نص على المسألة العارضة الجنائية فحسب، بينما أغفل بيان الإجراءات التي تتخذها المحكمة بعد أن تقرر وقف الدعوى، كما أنه أغفل بيان حجية الحكم الصادر من المحكمة المختصة في هذه المسألة، ولذلك نقترح أن يتدخل لوضع نص يعالج القصور، وذلك على غرار مسائل الأحوال الشخصية التي يتوقف عليها الفصل في الدعوى الجنائية (المواد 223، 224، 458 إجراءات جنائية). في النهاية تطرقت تلك الدراسة إلى أن المحاكم الفرنسية توقف الفصل في دعوى البلاغ الكاذب إلى أن يثبت كذب الوقائع المبلغ عنها بقرار من الجهات المختصة. ولا شك أن مذهب المشرع الفرنسي في هذا الصدد محل تقدير، ولذلك ندعو المشرع المصري أن يحذو حذوه.
تفريد العقوبة الجزائية في القانون الفيدرالي الأمريكي والنظام السعودي: دراسة مقارنة
Authors: Hashim Sahlool Jalal
Published: December 2021

تقدم هذه الدراسة تحليلًا مقارنًا عن تفريد العقوبة الجزائية في كل من القانون الجنائي الفيدرالي الأمريكي والنظام الجزائي السعودي. حيث تتناول بالشرح والمقارنة بين النظامين بعض أهم المحاور المرتبطة بتفريد العقوبة والتي تدور حول مفهومه وآلية العمل به. إذ يتم تفريد العقوبة في النظام الفيدرالي الأمريكي من خلال الرجوع إلى تطبيق القواعد الإرشادية لأحكام العقوبات الفيدرالية. أما في النظام الجزائي السعودي، فلا توجد قواعد إرشادية تنظيمية عامة لتفريد العقوبة الجزائية كتلك المعمول بها في النظام الفيدرالي الأمريكي. حيث إن القسم الأكبر من تفريد العقوبة في النظام الجزائي السعودي مرتبط بسلطة القاضي التقديرية التي يمارسها في حدود النص النظامي.
وتخلص الدراسة إلى أن للآلية المستخدمة في تفريد العقوبة وفق القواعد الإرشادية لأحكام العقوبات الفيدرالية دورًا وأثرًا كبيرًا في تنظيم السلطة التقديرية للقاضي الجنائي، الأمر الذي يعزز وحدة واتساق الأحكام القضائية الجزائية.
KORELASI VARIASI JENIS MAKANAN DAN LINGKUNGAN DENGAN POLA MAKAN ANAK USIA SEKOLAH
Authors: Khoirunnisa Fania Nurul , Indanah Indanah , Kusumastuti Diah Andriani , Ika Noviana
Published: December 2021

Berdasarkan data Badan Pelaporan dan Statistik (BPS) Propinsi Jawa Tengah tahun 2016 sebanyak lebih dari 20 % anak usia sekolah ditemukan mengalami masalah kesulitan makan. Gangguan kesulitan makan berpengaruh pada pemenuhan gizi, pertumbuhan fisik biomedik otak dan imunitas anak. Ketiga hal ini penting untuk menunjang kualitas hidup bagi anak sebagai generasi penerus bangsa. Gangguan sulit makan dapat diakibatkan karena semakin bertambahnya aktivitas seperti bermain, sekolah dan kurangnya peranan lingkungan sekitar anak sehingga terkadang mereka menjadi malas makan dan jajan sembarangan. Tujuan: Mengetahui korelasi antara variasi jenis makanan dan dukungan lingkungan dengan pola makan pada anak usia sekolah. Metode: Jenis penelitian analitik korelasional dengan pendekatan waktu cross sectional. Besar sampel 70 responden dengan teknik pengambilan sampel purposive sampling. Instrumen yang digunakan adalah kuesioner tentang jenis makanan, dukungan lingkungan dan pola makan. Analisis data uji statistik Spearman Rho. Hasil Penelitian : Mayoritas jenis makanan responden adalah kurang sehat sebanyak 54,3%, lingkungan yang mendukung sebanyak 54,3% dan mayoritas mengalami kesulitan makan tingkat sedang sebanyak 48,6%. Simpulan : Terdapat korelasi variasi jenis makanan (p=0,002 ; r = -0,698) dan lingkungan (p=0,001 ; r = -0, 687) dengan pola makan anak usia sekolah.