bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: Synthesis of Analogues of Daunosamine.
Authors: ST‐DENIS Y. , LAVALLEE J.‐F. , NGUYEN DIEU NGUYEN DIEU , ATTARDO G.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A New Synthesis of O‐Glycosides from Totally O‐Unprotected Glycosyl Donors.
Authors: FERRIERES V. , BERTHO J.‐N. , PLUSQUELLEC D.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Base‐Induced Ring Opening of a Sugar Derivative O‐Carbamate.
Authors: TAMION R. , MARSAIS F. , QUEGUINER G.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Cycloaddition Reactions of Carbohydrate Derivatives. Part 6. Quinolizidine Analogues of Castanospermine (XIII).
Authors: HERCZEGH P. , KOVACS I. , SZILAGYI L. , SZTARICSKAI F. , BERECIBAR A. , RICHE C. , CHIARONI A. , OLESKER A. , LUKACS G.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enantiopure N‐Acyldihydropyridones as Synthetic Intermediates: The First Asymmetric Synthesis of trans‐Decahydroquinoline Alkaloid (+)‐ 219A.
Authors: COMINS D. L. , DEHGHANI A.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Novel Synthesis of Arcyriaflavin‐A.
Authors: FONSECA A. P. , LOBO A. M. , PRABHAKAR S.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Convolutamydine A, a Novel Bioactive Hydroxyindole Alkaloid from Marine Bryozoan Amathia convoluta
Authors: KAMANO Y. , ZHANG H. , ICHIHARA Y. , KIZU H. , KOMIYAMA K. , PETTIT G. R.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A New and Efficient Synthesis of 8‐Hydroxypurine Derivatives by Dimethyldioxirane Oxidation.
Authors: SALADINO R. , CRESTINI C. , BERNINI R. , MINCIONE E. , CIAFRINO R.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Novel Route to the anti‐HIV Nucleoside d4T.
Authors: LIPSHUTZ B. H. , STEVENS K. L. , LOWE R. F.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: From (R)‐(+)‐Pulegone (I) to (2S,4R,6R,8S)‐2,4,8‐Trimethyl‐1,7‐ dioxaspiro(5.5)undecane (XIVa): A Unique Spiroacetal from the Insect Kingdom.
Authors: TU Y. Q. , MOORE C. J. , KITCHING W.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Synthesis of the Macrolide (+)‐Aspicilin by an Asymmetrically Catalyzed Macrocyclization of an ω‐Alkynal Ester.
Authors: OPPOLZER W. , RADINOV R. N. , DE BRABANDER J.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A New Synthetic Key Intermediate for Prostaglandins and Prostacyclins from Levoglucosan.
Authors: TAKATORI K. , KAJIWARA M. , YAMADA H. , TAKAHASHI T.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Different Approaches to the Asymmetric Synthesis of 1,3,6‐ Trisubstituted (XII) and 1,2,3,6‐Tetrasubstituted (XVI) Carbapenems from D‐Glucosamine.
Authors: ANAYA J. , BARTON D. H. R. , GERO S. D. , GRANDE M. , HERNANDO J. I. M. , LASO N. M.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Access to an Optically Pure Cyclosarkomycin by Conversion of the endo Adduct of (R)‐Allene 1,3‐Dicarboxylate and Cyclopentadiene.
Authors: IKEDA I. , KANEMATSU K.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Asymmetric Allylboration of 2‐N,3‐O‐Isopropylidene‐N‐Boc‐L‐serinal: Diastereoselective Synthesis of the Calicheamicin γI 1 Amino Sugar.
Authors: ROUSH W. R. , HUNT J. A.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Palladium(II)‐Catalyzed Construction of α‐Methylene‐γ‐ butyrolactones in Optically Active Form. Total Synthesis of (‐)‐ Methylenolactocin.
Authors: ZHU G. , LU X.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Taxol and Taxotere Side Chains by 2‐(Trimethylsilyl) thiazole Based Homologation of L‐Phenylglycine.
Authors: DONDONI A. , PERRONE D. , SEMOLA T.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Segment C of Tautomycin.
Authors: JIANG Y. , ICHIKAWA Y. , ISOBE M.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of the First Penicillin Derivatives with Medium‐Sized Lactam Ring and of Related Thiazolidines.
Authors: IMMING P.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Antibacterial Activity of New 1β‐Methyl Carbapenem Having a Thiazolo(3,2‐a)benzimidazole Moiety.
Authors: OH C.‐H. , HAM Y.‐W. , HONG S.‐Y. , CHO J.‐H.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Access to Unsaturated Chiral Epoxides. Part 2. Synthesis of a Component of the Sex Pheromone of Phragmatobia fuliginosa.
Authors: SOULIE J. , BOYER T. , LALLEMAND J. Y.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Intramolecular Radical Cyclization Approach to the Synthesis of Periplanone B.
Authors: JONAS D. , OEZLUE Y. , PARSONS P. J.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Stereoselective Approach to (‐)‐δ‐Multistriatin.
Authors: WITCZAK Z. J. , LI Y.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Very Short Asymmetric Synthesis of (1S,3S,5R)‐1,3‐Dimethyl‐2,9‐ dioxabicyclo(3.3.1)nonane via Tandem Enantioselective Reactions Promoted by One Chiral Borane.
Authors: KIYOOKA S. , KANEKO Y. , HARADA Y. , MATSUO T.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Absolute Stereochemistry of (+)‐Adociaquinones A (III) and B (IV).
Authors: HARADA N. , SUGIOKA T. , SOUTOME T. , HIYOSHI N. , UDA H. , KURIKI T.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Optically Active Diazacyclophosphamides: Novel Efficient Reagents for the Determination of the Absolute Configuration of Amines and Alcohols.
Authors: OSHIKAWA T. , YAMASHITA M. , KUMAGAI S. , SEO K. , KOBAYASHI J.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Potential Flame‐Retardant by Intumescence. Melaminium 2,6,7‐trioxa‐1‐ phosphabicyclo(2.2.2)octane‐4‐methoxy‐sulfates.
Authors: KIM J. K. , CHO Y. , JUNG O.‐S. , SOHN Y. S.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Inhibition of Pit Growth on an Iron Surface in a Borate Buffer Solution Containing Chloride Ion by Inhibitors Classified as Soft Bases in the HSAB Principle.
Authors: YAMAGUCHI M. , NISHIHARA H. , ARAMAKI K.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Sb‐Te System
Authors: GHOSH G.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Solubilities of Alkali Metal Salts and Precipitation of Cs+ from Aqueous Solution
Authors: FANNING J. C.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Schiff Base Macrocycles and Metallo‐Biosite Modelling
Authors: FENTON D. E.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Role of Macrocyclic Receptors in Organization of Metal Centers
Authors: BENCINI A. , BIANCHI A. , PAOLETTI P. , GARCIA ESPANA E.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Metallomacrocycles and ‐clefts: Receptors for Neutral Molecules and Anions
Authors: RUDKEVICH D. M. , HUCK W. T. S. , VAN VEGGEL F. C. J. M. , REINHOUDT D. N.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Specific Heat Studies on Metal Cluster Compounds
Authors: BROM H. B. , BAAK J. , DE JONGH L. J.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Clusters in Ligand Shells. Low‐Valent Organometallic Clusters
Authors: LONGONI G. , IAPALUCCI M. C.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Clusters in Ligand Shells. Metal‐Rich Large Clusters with P and N Ligands
Authors: SCHMID G.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Coordination Properties of the Bioligands Creatinine and Creatine in Various Reaction Media
Authors: MITEWA M.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Reactivities of Carbonyl Sulfide (COS), Carbon Disulfide (CS2) and Carbon Dioxide (CO2) with Transition‐Metal Complexes
Authors: PANDEY K. K.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Bonding Properties of Thiocyanate Groups in Copper(II) and Copper(I) Complexes
Authors: KABESOVA M. , BOCA R. , MELNIK M. , VALIGURA D. , DUNAJ‐JURCO M.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Recent Developments in the Chemistry of Early Transition‐Metal Porphyrin Compounds
Authors: BRAND H. , ARNOLD J.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Axial Coordination of Azaferrocene to Transition‐Metal Macrocyclic Complexes: Photoactivation of the Macrocycle
Authors: ZAKRZEWSKI J. , GIANNOTTI C.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Large Peptides in Solution
Authors: SAKAKIBARA S.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis, Structure, and Transport Properties of Fluorescent Derivatives of Conjugated Bile Acids
Authors: SCHTEINGART C. D. , EMING S. , TON‐NU H.‐T. , CROMBIE D. L. , HOFMANN A. F.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Nucleotides and Nucleic Acids
Authors: COSSTICK R. , COSSTICK A. M.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthetic and Conformational Studies of Branched and Lariat RNAs. Modeling the Lariat Formed in the Splicing Reaction
Authors: SUND C. , GLEMAREC C. , CHATTOPADHYAYA J.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Applications of Phosphatidylinositols and Their Analogues
Authors: SHASHIDHAR M. S.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Synthesis and Reactions of Pyrrole, Pyrazole, Triazole, Indole, Indazole, and Benzotriazole Nucleosides and Nucleotides
Authors: PREOBRAZHENSKAYA M. N. , KORBUKH I. A.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Syntheses and Reactions of Bicyclic Heterocyclic Nucleosides and Nucleotides
Authors: PFLEIDERER W.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Synthesis and Chemistry of Imidazole and Benzimidazole Nucleosides and Nucleotides
Authors: SHAW G.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Silicon Polymers: Formation and Application
Authors: AUNER N. , WEIS J.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemistry of Lantibiotics
Authors: SHIBA T.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Medium Ring Lactones
Authors: ROUSSEAU G.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catalytic Asymmetric Oxidations Using Optically Active (Salen) manganese(III) Complexes as Catalysts
Authors: KATSUKI T.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Layered Magnetic Structures: Interlayer Exchange Coupling and Giant magnetoresistance
Authors: FERT A. , GRUENBERG P. , BARTHELEMY A. , PETROFF F. , ZINN W.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 13C Nuclear Magnetic Resonance Spectrum Simulation
Authors: JURS P. C. , ANKER L. S. , BALL J. W.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Bioorganic Methods in Synthesis of Bioactive Terpenes and Other Natural Products
Authors: MORI K.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Dinuclear CuA Center in Cytochrome c Oxidase and N2O Reductase ‐ A Metal‐Metal Bond in Proteins
Authors: BERTAGNOLLI H. , KAIM W.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Syntheses of Zaragozic Acid
Authors: KOERT U.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Room Temperature Superconductors
Authors: SLEIGHT A.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: ′Peptoid′ Design
Authors: HORWELL D. C. , HOWSON W. , REES D. C.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: High Field Electron Spin Resonance
Authors: BRUNEL L. C. , BARRA A. L. , MARTINEZ G.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Transport Ordered 2D‐NMR Spectroscopy
Authors: JOHNSON C. S. JUN.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structure and Nomenclature
Authors: WEEDON B. C. L. , MOSS G. P.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Electronic Structure of Carotenoids
Authors: KOHLER B. E.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: UV/Visible Spectroscopy
Authors: BRITTON G.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: IR Spectroscopy
Authors: BERNHARD K. , GROSJEAN M.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: NMR Spectroscopy
Authors: ENGLERT G.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Mass Spectroscopy
Authors: ENZELL C. R. , BACK S.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
P2Y13 Receptor Is Critical for Reverse Cholesterol Transport
Authors: Fabre Aurélie C. , Malaval Camille , Addi Abduelhakem Ben , Verdier Céline , Pons Véronique , Serhan Nizar , Lichtenstein Laeticia , Combes Guillaume , Huby Thierry , Briand François , Collet Xavier , Nijstad Niels , Tietge Uwe J.F. , Robaye Bernard , Perret Bertrand , Boeynaems Jean-Marie , Martinez Laurent O.
Published: August 2010

A major atheroprotective functionality of high-density lipoproteins (HDLs) is to promote “reverse cholesterol transport” (RCT). In this process, HDLs mediate the efflux and transport of cholesterol from peripheral cells and its subsequent transport to the liver for further metabolism and biliary excretion. We have previously demonstrated in cultured hepatocytes that P2Y13 (purinergic receptor P2Y, G protein–coupled, 13) activation is essential for HDL uptake but the potential of P2Y13 as a target to promote RCT has not been documented. Here, we show that P2Y13-deficient mice exhibited a decrease in hepatic HDL cholesterol uptake, hepatic cholesterol content, and biliary cholesterol output, although their plasma HDL and other lipid levels were normal. These changes translated into a substantial decrease in the rate of macrophage-to-feces RCT. Therefore, hallmark features of RCT are impaired in P2Y13-deficient mice. Furthermore, cangrelor, a partial agonist of P2Y13, stimulated hepatic HDL uptake and biliary lipid secretions in normal mice and in mice with a targeted deletion of scavenger receptor class B type I (SR-BI) in liver (hypomSR-BI–knockoutliver) but had no effect in P2Y13 knockout mice, which indicate that P2Y13-mediated HDL uptake pathway is independent of SR-BI–mediated HDL selective cholesteryl ester uptake.

Conclusion:

These results establish P2Y13 as an attractive novel target for modulating RCT and support the emerging view that steady-state plasma HDL levels do not necessarily reflect the capacity of HDL to promote RCT. (Hepatology 2010)
Diagnosis of Hepatocellular Carcinoma in Cirrhosis by Dynamic Contrast Imaging: The Importance of Tumor Cell Differentiation
Authors: Iavarone Massimo , Sangiovanni Angelo , Forzenigo Laura Virginia , Massironi Sara , Fraquelli Mirella , Aghemo Alessio , Ronchi Guido , Biondetti Piero , Roncalli Massimo , Colombo Massimo
Published: August 2010

Dynamic contrast imaging techniques are considered the standard of care for the radiological diagnosis of hepatocellular carcinoma (HCC) in cirrhosis. However, the accuracy of radiological diagnosis depends largely on the degree of arterial hypervascularization, which increases with tumor size. Owing to the interplay and prognostic relevance of tumor vascularization and cell differentation, we asked ourselves whether tumor grade also affects the outcome of radiological diagnosis. Sixty-two HCCs (47 of which measured 1-2 cm) were consecutively detected in 59 patients with compensated cirrhosis under surveillance with ultrasound and confirmed by way of echo-guided biopsy and concurrent investigations with contrast-enhanced ultrasound (CE-US), computed tomography (CT), and gadolinium magnetic resonance imaging (MRI). Tumor cell differentiation was evaluated using Edmondson-Steiner criteria in liver cores of 0.9-5.0 cm (median 1.6 cm). Eighteen (29%) HCCs were grade I (1.5 cm), 28 (45%) were grade II (1.5 cm), 16 (26%) were grade III (1.8 cm), and none were grade IV. Contrast wash-in and wash-out were concurrently demonstrated in 21 (34%) tumors by way of CE-US, including three (16%) grade I and 18 (41%) grade II-III (

P

= 0.08); in 32 (52%) tumors by way of CT, including three (16%) grade I and 29 (66%) grade II-III (

P

= 0.0006); and 28 (47%) tumors by way of MRI, including three grade I (16%) and 25 (57%) grade II-III (

P

= 0.01). Among 1- to 2-cm tumors, the radiological diagnosis was achieved in two of 16 grade I and 17of 31 grade II-III tumors (

P

= 0.006).

Conclusion:

Tumor grade, a relevant predictor of disease severity, influences the accuracy of dynamic contrast techniques in the diagnosis of HCC. Hepatology 2010
Kinetics of Hepatitis B Surface Antigen Decline During 3 Years of Telbivudine Treatment in Hepatitis B e Antigen–Positive Patients
Authors: Wursthorn Karsten , Jung Mechthild , Riva Antonio , Goodman Zachary D. , Lopez Patricia , Bao Weibin , Manns Michael P. , Wedemeyer Heiner , Naoumov Nikolai V.
Published: August 2010

The impact of prolonged direct antiviral therapy on hepatitis B surface antigen (HBsAg) levels in patients with chronic hepatitis B is poorly understood. We quantitatively assessed serum HBsAg levels during 3 years of telbivudine treatment, as well as their relationship with virologic and biochemical characteristics in 162 hepatitis B e antigen–positive patients who maintained undetectable serum hepatitis B virus (HBV) DNA long-term. Telbivudine treatment progressively reduced serum HBsAg levels (mean ± SD) from baseline (3.8 ± 0.6 log10 IU/mL) to treatment week 24 (3.4 ± 0.7 log10 IU/mL), treatment year 1 (3.3 ± 0.8 log10 IU/mL), and treatment year 3 (3.0 ± 1.4 log10 IU/mL) (

P

<0.0001). In this patient population, HBsAg loss was observed in nine (6%) of 162 patients through year 3. During the first year of treatment, three patterns of HBsAg decline were observed: rapid (≥1 log10 IU/mL) in 32 patients, slow (0-1 log10 IU/mL) in 74 patients, and steady levels in 56 patients. These findings were associated with different likelihoods of HBsAg loss during long-term telbivudine therapy. Eight of 32 patients with rapid HBsAg decline versus none of 56 patients with steady HBsAg levels achieved HBsAg loss at year 3 (

P

= 0.0024). HBV genotype was a significant determinant for HBsAg kinetics, with the fastest decline in genotype A patients. In patients with subsequent HBsAg loss, viral antigens were already undetectable in liver biopsy samples after 1 year of treatment. This was associated with markedly enhanced antiviral T cell reactivity.

Conclusion:

In patients who have effective suppression of viral replication during telbivudine treatment, a rapid decline in serum HBsAg levels during the first year may identify those with a greater likelihood of achieving HBsAg clearance. (Hepatology 2010
Tuning cell adhesion on titanium with osteogenic rosette nanotubes
Authors: Zhang Lijie , Hemraz Usha D. , Fenniri Hicham , Webster Thomas J.
Published: August 2010

Self‐assembled rosette nanotubes (RNTs), obtained from a twin G∧C base functionalized with lysine‐arginine‐serine‐arginine [KRSR–(G∧C)2], were designed and investigated as bioactive coatings on titanium. These results were compared to RNTs derived from Lysine–G∧C (K–G∧C), Arg‐Gly‐Asp–G∧C (RGD–G∧C), and aminobutane–(G∧C)2 [AB–(G∧C)2]. The results from this study revealed that these materials had excellent cytocompatibility properties as they enhanced osteoblast (bone forming cell) adhesion when coated on titanium. In particular, KRSR and RGD functionalized RNTs coated on titanium promoted the greatest osteoblast densities relative to untreated titanium. Furthermore, KRSR functionalized RNTs selectively improved osteoblast adhesion relative to fibroblast (soft‐tissue forming cell) and endothelial (cells that line the vascular) cell adhesion. In contrast with these results, RNTs obtained from an unfunctionalized twin base [AB–(G∧C)2], RGD–G∧C co‐assembled with K–G∧C and K‐G∧C significantly enhanced endothelial cell attachment, which may find applications in the vascularization of newly formed bone tissue. In summary, these studies suggest that the surface of orthopedic implant materials (such as titanium) could be tailored to promote selective cell adhesion using biologically‐inspired nanotubular structures functionalized with osteogenic compounds. © 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2010.
Beneficial effects of granulocyte‐colony stimulating factor on small‐diameter heparin immobilized decellularized vascular graft
Authors: Zhou Min , Liu Zhao , Li Kun , Qiao Wei , Jiang Xuefeng , Ran Feng , Qiao Tong , Liu Changjian
Published: August 2010

Autologous recellularization of decellularized scaffolds is a promising challenge in the field of tissue‐engineered vascular graft and could be boosted by endothelial progenitor cells (EPCs). The purpose of this study was to examine the effects of granulocyte‐colony stimulating factor (G‐CSF) treatment on this process. Heparin immobilized decellularized grafts were fabricated and implanted into 48 rats, of which 25 rats received G‐CSF (50 ug/kg/day) for 14 days after operation (G‐CSF group) and other 23 received saline serving as control. Five animals of each group were euthanized at 2 weeks for analysis of early graft endothelialization; whereas the rest were investigated by Doppler ultrasound to monitor the graft patency rate up to 6 months. After 14 days of G‐CSF administration, the number of CD/CD progenitor cells was increased by 16.2 folds, and endothelial cell‐specific immunostaining revealed an enhancement of early endothelialization in G‐CSF group. After 6 months of implantation, the G‐CSF treated grafts exhibited a significantly smaller hyperplastic neointima area compared with the controls, not only at midportion (0.38 ± 0.02 vs. 0.47 ± 0.07 mm2, p < 0.0001), but also at distal anastomosis (0.42 ± 0.04 vs. 0.70 ± 0.13 mm2, p < 0.0001). Moreover, G‐CSF treated grafts had a higher patency rate compared with the control animals (19/20 vs. 12/18, p = 0.005). In conclusion, G‐CSF‐induced mobilization of circulating EPCs regenerated endothelium and inhibited neointimal hyperplasia of small‐diameter heparinized decellularized vascular graft. This cytokine therapy may be a feasible strategy for the improvement of patency rate of the novel allogeneic graft. © 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2010.
Evaluation of dense polylactic acid/beta‐tricalcium phosphate scaffolds for bone tissue engineering
Authors: Yanoso‐Scholl Laura , Jacobson Justin A. , Bradica Gino , Lerner Amy L. , O'Keefe Regis J. , Schwarz Edward M. , Zuscik Michael J. , Awad Hani A.
Published: August 2010

Advances in biomaterial fabrication have introduced numerous innovations in designing scaffolds for bone tissue engineering. Often, the focus has been on fabricating scaffolds with high and interconnected porosity that would allow for cellular seeding and tissue ingrowth. However, such scaffolds typically lack the mechanical strength to sustain in vivo ambulatory stresses in models of load bearing cortical bone reconstruction. In this study, we investigated the microstructural and mechanical properties of dense PLA and PLA/beta‐TCP (85:15) scaffolds fabricated using a rapid volume expansion phase separation technique, which embeds uncoated beta‐TCP particles within the porous polymer. PLA scaffolds had a volumetric porosity in the range of 30 to 40%. With the embedding of beta‐TCP mineral particles, the porosity of the scaffolds was reduced in half, whereas the ultimate compressive and torsional strength were significantly increased. We also investigated the properties of the scaffolds as delivery vehicles for growth factors in vitro and in vivo. The low‐surface porosity resulted in sub optimal retention efficiency of the growth factors, and burst release kinetics reflecting surface coating rather than volumetric entrapment, regardless of the scaffold used. When loaded with BMP2 and VEGF and implanted in the quadriceps muscle, PLA/beta‐TCP scaffolds did not induce ectopic mineralization but induced a significant 1.8‐fold increase in neo vessel formation. In conclusion, dense PLA/beta‐TCP scaffolds can be engineered with enhanced mechanical properties and potentially be exploited for localized therapeutic factor delivery. © 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2010.
Cartilage regeneration by bone marrow cells‐seeded scaffolds
Authors: Wegener Bernd , Schrimpf Florian M. , Bergschmidt Philipp , Pietschmann Mathias F. , Utzschneider Sandra , Milz Stefan , Jansson Volkmar , Müller Peter E.
Published: August 2010

Different approaches exist for the treatment of small articular cartilage defects. Several studies show comparable results for autologous chondrocyte implantation (ACI) and microfracture. Unfortunately, the fibrocartilage resulting from microfracture has neither the structure nor the mechanical properties of hyaline cartilage, even though the adult mesenchymal stem cells, which immigrate into the defect, are supposed to differentiate into chondrocytes. This study was performed to examine the capacity of a resorbable implant made from polylactide‐co‐glycolide acid (PGLA)‐fleece combined with autologous bone marrow cells fixed with a fibrin/thrombin‐clot in the weight‐bearing area of the femoral condyle of mature sheep. For this study, six defects were treated with either the PGLA‐implant alone or with a combination of the implant with added fibrin glue or were left untreated to serve as controls. The animals were sacrificed after 12 weeks; the operated knees were removed and examined by measuring the covering of the defect with cartilaginous tissue and according to the score of O'Driscoll. Additional criteria such as immunolabeling for collagen II and aggrecan were included. Results showed that no improvement of the tissue quantity or quality could be achieved by increasing the cell load of the implant with cells fixed by fibrin glue. © 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2010.
Biomimetic organic–inorganic nanocomposite coatings for titanium implants. In vitro and in vivo biological testing
Authors: Schade R. , Sikirić M. Dutour , Lamolle S. , Ronold H. J. , Lyngstadass S. P. , Liefeith K. , Cuisinier F. , Füredi‐Milhofer H.
Published: August 2010

Recently described organic–inorganic nanocomposite coatings of the chemical composition: (PLL/PGA)10CaP[(PLL/PGA)5CaP]4 (coating A) and (PLL/PGA)10CaP[(PLL/PGA)5CaP]4(PLL/PGA)5 (coating B), applied to chemically etched titanium plates, have been tested by extensive cell culture tests and in vivo biological experiments, with uncoated titanium plates serving as controls. Before testing, coated samples were stored for extended periods of time (from 2 weeks to 8 months) under dry, sterile conditions. Cells of the cell‐lines MC3T3‐E1 and/or SAOS‐2 were used for the following cell culture tests: initial adhesion (4 h) and proliferation (up to 21 days), cell activity (XTT test), morphology, synthesis of collagen type I and alkaline phosphatase activity (all incubation up to 21 days). In addition, coating B was tested against uncoated control in a validated in vivo pull‐out model in rabbit tibia. The results of both in vitro and in vivo experiments show excellent biological properties of chemically etched titanium which are even surpassed by surfaces covered with coating B. Thus, after 8 weeks of healing the implants coated with B were significantly better attached to the cortical bone of rabbit thibiae than uncoated titanium controls with more than twice the force needed to detach coated implants. However, coating A (top crystal layer) had an adverse effect on both cell proliferation and activity, which is explained by morphological observations, showing inhibited spreading of the cells on its rough surfaces. The results also show the remarkable stability of the coatings when shelved under dry and sterile conditions. © 2010 Wiley Periodicals, Inc. J Biomed Mater Res Part A, 2010.