bluuebunny/crossref_metadata_2025 huggingface dataset:
A COVID-19 em profissionais de enfermagem: um arcabouço de incertezas
Authors: Andrade Cinthia Rafaela Amaro Gonçalves , Costa Laís de Miranda Crispim , Lúcio Ingrid Martins Leite , Lima Herika do Nascimento , Nascimento Renata Lira do
Published: July 2022

Trata-se de uma reflexão cujo objetivo foi apresentar e discutir o percurso de busca do referencial teórico para análise da dissertação de mestrado intitulada: “O adoecimento de profissionais da enfermagem pela Covid-19”. A discussão ocorreu a partir de três categorias temáticas: A COVID-19 e os profissionais da enfermagem; As teorias de enfermagem; e O adoecimento dos profissionais de enfermagem à luz da Teoria da Incerteza da Doença. A reflexão esclareceu que o adoecimento por COVID-19 se apresenta com uma imensidão de incertezas, que repercutem como falta de clareza e inadequação no estado cognitivo, evidenciando a Teoria da Incerteza da Doença como um referencial teórico adequado para leitura deste fenômeno.

Descritores: Enfermagem Baseada em Evidências, Teoria de Enfermagem, Incerteza.

 

COVID-19 in nursing professionals: a framework of uncertainties

Abstract: This is a reflection whose objective was to present and discuss the search for the theoretical framework for the analysis of the master's thesis entitled: "The illness of nursing professionals by Covid-19". The discussion took place from three thematic categories: COVID-19 and nursing professionals; Nursing theories; and The illness of nursing professionals in the light of the Disease Uncertainty Theory. The reflection clarified that illness due to COVID-19 presents an immensity of uncertainties, which reflect as a lack of clarity and inadequacy in the cognitive state, evidencing the Disease Uncertainty Theory as an adequate theoretical framework for reading this phenomenon.

Descriptors: Evidence-Based Nursing, Nursing Theory, Uncertainty.

 

COVID-19 en profesionales de enfermería: un marco de incertidumbres

Resumen: Se trata de una reflexión cuyo objetivo fue presentar y discutir la búsqueda del marco teórico para el análisis de la tesis de maestría titulada: "La enfermedad de los profesionales de enfermería por Covid-19". La discusión se desarrolló a partir de tres categorías temáticas: COVID-19 y profesionales de enfermería; Teorías de enfermería; y La enfermedad de los profesionales de enfermería a la luz de la Teoría de la Incertidumbre de la Enfermedad. La reflexión aclaró que la enfermedad por COVID-19 presenta una inmensidad de incertidumbres, que se reflejan como falta de claridad e insuficiencia en el estado cognitivo, evidenciando la Teoría de la Incertidumbre de la Enfermedad como un marco teórico adecuado para la lectura de este fenómeno.

Descriptores: Enfermería Basada en la Evidencia, Teoría de Enfermería, Incertidumbre.
Effect of Collection Period and Irrigation Process on Antioxidant Activity and Phenolic Compounds of Olive Leaves
Authors: USLU Nurhan , ÖZCAN Mehmet Musa
Published: July 2022

Olive leaves have drawn attention because of their contents of bioactive compounds that exhibit antioxidant activity. The aim of this study was to investigate the impact of irrigation on the phenolic compounds and antioxidant activity of olive leaves belonged to different varieties collected between September and December in irrigated and rainfed orchards. Principal components analysis (PCA) was used to explain the effect of variables. The highest total phenolic content was determined in irrigated Ayvalık leaves (1945 mg/100g). Results showed that olive leaves contained significant amounts of flavonoids, ranging from 6379 to 159046 mg/100g. However, differences in antioxidant activity were generally between 1 and 2% regarding irrigation, collection time, and variety. Luteolin-7-glucoside (273-1461 mg/100g) was the main phenolic compound of olive leaves, followed by verbascoside (399-1002 mg/100g). The influence of irrigation showed differences in the amounts of phenolic compounds among the cultivars.
Dairy Products in Space Nutrition and Potential Processing of Dairy Products with 3D/4D Printers as a Space Food
Authors: BODRUK Anıl , ACAR Furkan
Published: July 2022

Dairy products, which have been used for many years in the nutrition of individuals, have many benefits for human health. Due to recent developments such as climate changes, raw material deficiency and increased population, humankind has been forced to seek alternative resources from the space in the latest decades. Yet, in the space, feeding has for so long been world-centered and effectuated short term. Due to swift rise of 3-dimensional and 4-dimensional printer technologies at the end of 20th century, onset of 21st century, quick expansion, and wide use of such technologies, their use in space missions and space-food production has come to the surface. Within the context of this study, data related to utilizing dairy products as a space food and data on using 3-dimensional (3D) and 4-dimensional (4D) printers to generate these products in space mission were collected and evaluated in the review.
Data mining of Chain convenience stores location
Authors: Shi Yingfeng , Chen Xiuchen
Published: July 2022

Based on the knowledge of convenience stores, this paper comprehensively probes the influencing factors of their location, and constructs and analyses their location mode. The initial evaluation system was put forward, which consists of 5 primary indexes and 14 secondary indexes. The primary index is divided into population, traffic, competition, self-factors and others. After determining three different location evaluation systems, the location model of chain convenience stores is constructed and verified based on the data of Nanjing. The verification of the model shows that the accuracy of the location model of a convenience store is 90.3%, which indicates that the location model proposed in this paper has high accuracy and practicability.
Supporting military maintenance and repair with additive manufacturing
Authors: Rautio Samu , Valtonen Ilari
Published: July 2022

The purpose of the study is to explore whether Additive Manufacturing (AM) can support the military maintenance and repair of combat troops at isolated tactical level maintenance sites. The study also sought an explanation as to how AM could be organised in military logistics. The subject was approached from a systemic perspective. A system dynamics modelling was used as an impact assessment method. When selecting the parameters used in the model, the 3D printing data of the spare parts printed on the MTLB armoured personnel carrier (APC) were utilised. With simulation, we identified several key nodes for replacing or enhancing conventional military logistics with an AM added supply chain. As a result of the study, it was identified that by adding metal AM to the mechanised battalion organic maintenance and repair at the field level, it can produce spare parts whose use will improve APC recovery in the event of failure. We found that the relatively slow production speed of AM is the most influential factor in the use of the method. This study introduces a new perspective on reviewing the potential of AM in military logistics.
The Banjar Elite Response to Ethical Policy 1900—1942 on Education Aspect
Authors: Hasanah Noor
Published: July 2022

Keberadaan dan perkembangan lembaga pendidikan di Banjar, Kalimantan Selatan, sebagai reaksi terhadap Etische Politiek (Kebijakan Etis Belanda) relatif pesat. Namun, penelitian terkait hal tersebut masih terkesan minim, seringkali hanya berupa biografi tokoh, ulama, dan sejarah Islam yang diyakini oleh masyarakat Banjar. Penelitian ini bertujuan untuk membuktikan bahwa meskipun kolonial Belanda menerapkan Kebijakan Etis sebagai pembatasan hak pendidikan pribumi, para elit ulama, cendekiawan, dan pedagang menanggapi aturan tersebut dengan membentuk lembaga pendidikan tandingan, baik yang berbasis pada nasionalisme dan yang berbasis Islam. Penelitian ini menggunakan pendekatan sosio-intelektual sejarah dan historis-kritis. Metode ini digunakan karena mengamati sejarah gerakan pendidikan di Banjar sebagai respon terhadap pendidikan yang diselenggarakan oleh Belanda. Pendekatan ini bertujuan untuk mendeskripsikan peristiwa sejarah yang berkaitan langsung dengan pendidikan di Banjar. Tahapan penelitian ini antara lain: heuristik, verifikasi atau kritik, interpretasi, dan historiografi. Selanjutnya, data yang ditemukan ditulis secara kronologis menurut catatan sejarah para penulis sejarah. Hasil penelitian menunjukkan bahwa Kebijakan Etis pada aspek pendidikan tidak berpengaruh secara signifikan terhadap masyarakat Banjar karena mereka lebih memilih madrasah atau pesantren untuk sekolah, serta sekolah nasionalis, yang secara konsisten menumbuhkan rasa cinta tanah air dan semangat kemerdekaan.

The existence and development of educational institutions in Banjar, South Kalimantan, as a reaction to Etische Politiek (Dutch Ethical Policy) are relatively rapid. However, the research related to it still seems minimal, often only in the form of biographies of figures, scholars, and the history of Islam believed by the Banjarese. The research aims to prove that although the Dutch colonials applied the Ethical Policy as a limitation of indigenous education rights, the elites who were ulama (Islamic clerics), intellectuals, and traders responded to these rules by forming rival educational institutions, both those based on nationalism and those based on Islam. This research uses a socio-intellectual history and historical-critical approach. These methods are used because it observes the history of the education movement in Banjar as a response to education organized by the Dutch. This approach aims to describe historical events that are directly related to education in Banjar. This research takes the following steps: heuristics, verification or criticism, interpretation, and historiography. Then, the data found are written chronologically according to the historical records of the historical writers. The research shows that Ethical Policy on the education aspect did not significantly influence the Banjarese because they preferred madrasa or pesantren for school, as well as nationalist schools, which consistently fostered a sense of love for the homeland and the spirit of independence.
A Gödel Calculus for Linear Temporal Logic
Authors: Aguilera Juan Pablo , Diéguez Martín , Fernández-Duque David , McLean Brett
Published: July 2022

We consider GTL, a variant of linear temporal logic based on Gödel-Dummett propositional logic. In recent work, we have shown this logic to enjoy natural semantics both as a fuzzy logic and as a superintuitionistic logic. Using semantical methods, the logic was shown to be PSPACE-complete. In this paper we provide a deductive calculus for GTL, and show this calculus to be sound and complete for the above-mentioned semantics.
Normalisations of Existential Rules: Not so Innocuous!
Authors: Carral David , Larroque Lucas , Mugnier Marie-Laure , Thomazo Michaël
Published: July 2022

Existential rules are an expressive knowledge representation language mainly developed to query data. In the literature, they are often supposed to be in some normal form that simplifies technical developments. For instance, a common assumption is that rule heads are atomic, i.e., restricted to a single atom. Such assumptions are considered to be made without loss of generality as long as all sets of rules can be normalised while preserving entailment. However, an important question is whether the properties that ensure the decidability of reasoning are preserved as well. We provide a systematic study of the impact of these procedures on the different chase variants with respect to chase (non-)termination and FO-rewritability. This also leads us to solve open problems related to chase termination of independent interest.
Automatic Synthesis of Dynamic Norms for Multi-Agent Systems
Authors: Alechina Natasha , De Giacomo Giuseppe , Logan Brian , Perelli Giuseppe
Published: July 2022

Norms have been widely proposed to coordinate and regulate multi-agent systems (MAS) behaviour. We consider the problem of synthesising and revising the set of norms in a normative MAS to satisfy a design objective expressed in Alternating Time Temporal Logic (ATL*). ATL* is a well-established language for strategic reasoning, which allows the specification of norms that constrain the strategic behaviour of agents. We focus on dynamic norms, that is, norms corresponding to Mealy machines, that allow us to place different constraints on the agents' behaviour depending on the state of the norm and the state of the underlying MAS. We show that synthesising dynamic norms is (k + 1)-EXPTIME, where k is the alternation depth of quantifiers in the ATL* specification. Note that for typical cases of interest, k is either 1 or 2. We also study the problem of removing existing norms to satisfy a new objective, which we show to be 2EXPTIME-complete.
Conservative Extensions for Existential Rules
Authors: Jung Jean Christoph , Lutz Carsten , Marcinkowski Jerzy
Published: July 2022

We study the problem to decide, given sets T1, T2 of tuple-generating dependencies (TGDs), also called existential rules, whether T2 is a conservative extension of T1. We consider two natural notions of conservative extension, one pertaining to answers to conjunctive queries over databases and one to homomorphisms between chased databases. Our main results are that these problems are undecidable for linear TGDs, undecidable for guarded TGDs even when T1 is empty, and decidable for frontier-one TGDs.
On Syntactic Forgetting with Strong Persistence
Authors: Berthold Matti
Published: July 2022

It is generally agreed upon that so-called strong persistence (SP) captures best the essence of forgetting in logic programming. While classes of operators, such as F_R and F_SP, that satisfy immediate relaxations of (SP), and in the case of F_SP, even (SP) whenever possible, have been characterized semantically, many practical questions have yet to be addressed.
This technical paper aims to answer one of them: How can atoms be forgotten from a program without having to calculate its exponential number of models? To this end, we introduce two concrete representatives of F_R and F_SP that forget sets of atoms by syntactical manipulation of a program’s rules. This may in many cases prevent exponential blowups and produce a forgetting result that is close to the original program.
Explaining Causal Models with Argumentation: the Case of Bi-variate Reinforcement
Authors: Rago Antonio , Baroni Pietro , Toni Francesca
Published: July 2022

Causal models are playing an increasingly important role in machine learning, particularly in the realm of explainable AI. We introduce a conceptualisation for generating argumentation frameworks (AFs) from causal models for the purpose of forging explanations for the models’ outputs. The conceptualisation is based on reinterpreting desirable properties of semantics of AFs as explanation moulds, which are means for characterising the relations in the causal model argumentatively. We demonstrate our methodology by reinterpreting the property of bi-variate reinforcement as an explanation mould to forge bipolar AFs as explanations for the outputs of causal models. We perform a theoretical evaluation of these
argumentative explanations, examining whether they satisfy a range of desirable explanatory and argumentative properties.
Stream Reasoning with Cycles
Authors: Mantenoglou Periklis , Pitsikalis Manolis , Artikis Alexander
Published: July 2022

Temporal specifications, such as those found in multi-agent systems, often include cyclic dependencies. Moreover, there is an increasing need to evaluate such specifications in an online manner, upon streaming data. Consider, for example, the online computation of the normative positions of the agents engaging in an e-commerce protocol. We present a formal computational framework that deals with cyclic dependencies in an efficient way. Moreover, we demonstrate the effectiveness of our framework on large synthetic and real data streams, from the fields of multi-agent systems and composite event recognition.
Pirólisis: una revisión de conceptos y aplicaciones en la gestión de residuos sólidos
Authors: Vilca Karla , Rodríguez Stephani , Atarama Ulvio , Cueva Cristian , Concha Wendy Jackeline , Atausupa Miguel Angel , Gosgot Wildor
Published: July 2022

La gestión de residuos sólidos es un desafío ambiental a nivel mundial debido a que generan contaminación de aguas y suelos, así como emisiones de gas de efecto invernadero, lo cual se incrementará con el crecimiento de las ciudades y población. Es por ello, que el tratamiento de estos, especialmente la fracción orgánica, mediante el proceso de pirólisis se presenta como una alternativa sostenible con beneficios significativos como la obtención de subproductos, como el biocarbón, que tiene diversos campos de aplicación en aguas, suelos y cambio climático. En esta revisión, se explora en la primera sección los procesos de pirólisis, materia prima y subproductos. En la siguiente sección se analizan las aplicaciones del biocarbón, como subproducto, en el tratamiento de agua, suelo y reducción de gases de efecto invernadero. Finalmente, realiza una análisis técnico, económico y ambiental del proceso pirolítico. Por ende, la gestión de la fracción orgánica de residuos sólidos municipales a través de pirólisis, es un proceso sostenible, rentable y replicable.
Análisis energético de un sistema híbrido fotovoltaico-térmico bajo las condiciones climáticas de Chachapoyas, Amazonas, Perú
Authors: Jalca Cabañas Eráclides , Espinoza Canaza Fernando , Gosgot Angeles Wildor , Rivera López Rosalynn Yohanna
Published: July 2022

El aprovechamiento de la energía solar es una alternativa para cubrir la demanda energética. En cualquier parte del mundo. La investigación se enfocó en determinar la eficiencia térmica y eléctrica de un nuevo diseño de sistema híbrido fotovoltaico/térmico, compuesto de un colector de 1,6 m2, una parrilla de tubos de policloruro de vinilo clorado (CPVC) de ½”, con cubierta superior de un panel solar monocristalino de 315 W y un tanque de 70 litros para almacenar el agua; bajo las condiciones climáticas de Chachapoyas, a un ángulo de inclinación de 15° orientado norte-sur, entre las de 8:00 y 16:00 horas, durante 11 días en el mes de enero de 2021. Para comprobar la eficiencia térmica del sistema propuesto, se utilizó un sistema solar térmico convencional, con los mismos componentes, excepto la cubierta del colector (vidrio transparente de 4 mm de diámetro), mientras que para comparar la eficiencia eléctrica se usó un panel fotovoltaico (FV). Los resultados muestran que el nuevo sistema propuesto tuvo una eficiencia de 5% menor al sistema térmico convencional pero lo suficiente para calentar el agua, por otro lado, se tuvo una ganancia de 10% eficiencia energética del panel solar, por lo que, se concluye que este nuevo sistema, permite aprovechar mejor la radiación solar, para generar energía térmica y eléctrica de forma simultánea, además de optimizar el área de instalación.
Der sächsische Adel an den Universitäten Europas. Universitätsbesuch, Studienalltag und Lebenswege in Spätmittelalter und beginnender Frühneuzeit
Authors: Münnich Fanny
Published: July 2022

Im späten Mittelalter befand sich der Adel unter steigendem Veränderungsdruck: Durch Kriege, Konjunkturen, neue Vorstellungen und soziale Gruppen wurde der Adel als Herrschaftsklasse kritisch hinterfragt. Der Humanismus schließlich bot Anlass zu dem Gedanken, dass der Geburtsadel dem 'Geistesadel' der Gelehrten unterlegen war. Während der Adel selbst die Möglichkeit gelehrter Bildung zunächst ausschloss, ersetzten nichtadlige Gelehrte Mitglieder adliger Familien in deren Aufgaben und betonten so die Chance eines gesellschaftlichen Aufstieges durch Bildung. Fanny Münnich zeigt am Beispiel des sächsischen Niederadels das wandelnde Bildungsverhältnis und zeichnet den Studienalltag der ersten adligen Studierenden an den Universitäten und ihre spätere Lebenswege nach. Sie untersucht das Bildungsverhalten des Adels unter dem Kontext der Aufrechterhaltung des gesellschaftlichen Status und stellt dar, wie sich die Mitglieder des sächsischen Adels an die veränderten Vorstellungen anpassten.
Intralesional immunotherapy for non-genital warts: A systematic review and meta-analysis
Authors: Ju Hyun Jeong , Park Hye Ree , Kim Ji Yoon , Kim Gyong Moon , Bae Jung Min , Lee Ji Hae
Published: July 2022

Background

Intralesional immunotherapy has been reported to be effective for warts and to show good safety profiles, but this has not yet been systematically studied.

Aims

To determine the efficacy and safety of intralesional immunotherapy for treating non-genital warts.

Methods

We comprehensively searched the MEDLINE, Embase, Web of Science and Cochrane Library databases from the times of their inception to January 3, 2020. The primary outcome was the rate of complete response of all lesions. The distant complete response rate of warts located in an anatomically different body part and the recurrence rate were also analyzed.

Results

A total of 54 prospective studies was ultimately included. The immunotherapeutic agents used were Mycobacterium w vaccine, measles, mumps and rubella vaccine, purified protein derivative, Candida antigen, interferon, bacillus Calmette-Guérin vaccine and others. The pooled rate of complete response among all patients with non-genital warts treated using intralesional immunotherapy was 60.6% (95% confidence interval 54.8–66.5%). The pooled recurrence rate was 2.0% (95% confidence interval, 1.1–2.9%). All reported adverse events were mild and transient.

Limitations

The heterogeneity among studies

Conclusion

Intralesional immunotherapy is suggested for use in patients with multiple warts, given its promising results, good safety profile and low recurrence rate.
Conversion of palm oil sludge to biodiesel using sulphuric acid as catalyst
Authors: Manjunath R. , Narula Archna , R.R. Siva Kiran
Published: July 2022

The present study focuses on utilizing palm oil sludge (POS) as low-cost feed stock for biodiesel production. The esterification reaction was performed by varying sulphuric acid dosage (2–5% wt), methanol to palm oil sludge molar ratio (3.5:1–9.5:1), reaction time (30–120 min), temperature 60 C and stirred speed 400 rpm. The free fatty acids (FFA) considerably reduced from 17.76% to 1.34% and maximum esters yield was observed to be 91.56% at optimal conditions, 4 wt % H2SO4, methanol to palm oil sludge ratio 7.5:1 and 60 min. The biodiesel was produced by transesterification process by varying sodium hydroxide catalyst concentration from 0.25 to 1.5 wt%. The maximum biodiesel yield of 92.2% was obtained at 0.25 wt% of NaOH. The biodiesel was tested for the fuel properties as per the IS 1448 protocol and compared with normal diesel fuel with reference to ASTM D6751 standards.
Development and validation of a sensitive LCMS/MS method for the simultaneous quantification of Azelnidipine and Chlorthalidone in human plasma
Authors: Phaneendra Rao P.G. , Sreenivasa Rao Battula
Published: July 2022

Highly resolved, selective and sensitive liquid chromatography/tandem mass spectrometry (LC–MS/MS) method was optimised for the simultaneous quantification and recently approved combined medication for the treatment of hypertension viz. azelnidipine and chlorthalidone in spiked human plasma. The study utilizes nifedipine as internal standard. In the extraction of analytes from spiked plasma, acetonitrile was used to induce protein precipitation and then liquid – liquid extraction was carried using ethyl acetate solvent followed by the LCMS-MS analysis. The analytes were separated on Inertsil ODS C18 (4.6 mm×100 mm, 5 μm) column at room temperature with 65:35 (v/v) ratio of acetonitrile and 0.1% formic acid as the mobile phase at 0.5 mL/min flow rate. Detection was performed on a triple quadrupole mass spectrometer employing electrospray ionization technique, operating in multiple reaction monitoring with the transitions of m/z 583 → 331, 339 → 321 and 347 → 328 respectively for azelnidipine, chlorthalidone and nifedipine. The analytes were detected at a retention time of 1.72 min, 2.62 min and 3.12 min respectively for azelnidipine, chlorthalidone and nifedipine and the analysis was completed within run time of 5 min. The analysis was carried in the calibration range of 5-500 ng/mL with a very sensitive detection limit of 1.5 ng/mL. The method was validated as per FDA guidelines for bioanalytical method validation and the results in all the validation parameters were in the acceptable limit. Results proved that the method was selective, sensitive, accurate, precise and stable and hence can be applicable for the routine analysis of azelnidipine and chlorthalidone in biological samples.
Pharmacognostic, Phytochemical and Optimization Studies of Hydroalcoholic Extract of Terminalia catappa Linn. Dried Fruit
Authors: Saharan Anjali , Dureja Harish , Dhiman Anju
Published: July 2022

The dried fruits of Terminalia catappa are well known for their virtuous medicinal value. The various phytoconstituents found in this plant are reported to have phytochemicals such as carbohydrates, alkaloids, glycosides, saponins, flavonoids, tannins and phenolic compounds. The present research work was performed to evaluate the pharmacognostic studies such as phytochemical standardization of the whole dried fruits of Terminalia catappa Linn. Morphological evaluation, moisture content determination, extractive values, ash values such as sulphated ash value, water-soluble ash, acid insoluble ash, total ash were determined. To ensure the safety of the constituents and plant, heavy metal analysis test was performed using atomic absorption spectrometry. Based on the above reports of extractive value, the hydroalcoholic solvent was quantified. The extraction was carried out using the Box Behnken design of optimization with 3 variables using the microwave-assisted method of extraction. Quantification of the optimized extracts was performed using high-performance liquid chromatography. Based on these findings, this species can be further explored in terms of pharmacological investigation and standardization for quality, purity and sample identification.
Application of response surface methodology for optimizing process parameters for the removal of Pb and Cu by Acacia Concinna from contaminated soil
Authors: Ugwu Elijah Chibuzo , Gupta Bhaskar Sen , Adebayo Adeloye , Martínez-Villegas Nadia
Published: July 2022

This work investigates the remediation of lead (Pb) and copper (Cu) contaminated soil in batch washing experiments by using biodegradable saponin from the plant, Acacia concinna is commonly known as shikakai. The results indicate that the optimal values for the surfactant concentration (Conc), pH and soil-solution ratio (SSR) are 3.3, 3 and 28.78 respectively for Pb removal while the corresponding values for Cu are 3.70, 3 and 30.30 respectively. The predicted Pb removal efficiency was 78.17% while that for the Cu was 92.96%. The influencing parameters: conc., pH and SSR were optimised using Response surface methodology (RSM) based on the Box-Behnken design (BBD). A second-order quadratic polynomial model was used to correlate the effect of these three independent variables. The ANOVA analysis and Pareto plot were generated using Minitab 18 software show that conc., SSR and pH were all significant (P < 0.05) for Pb and Cu removal while the conc. and pH were significant (P< 0.05) for Cu removal. The lower values of S (1.87 and 4.5) and higher values of R2 (99.6% and 98.70%), adjusted R2 (98.96% and 96.37%) and predicted R2 (95.69% and 80.10%) suggested a good fit of the model to the experimental data. The high correlation between the predicted value of 78.17% and 92.96% and the experimental value of 78.79% and 90.79% for Pb and Cu respectively further confirm the adequacy as well as the applicability of this model. The results show the application of RSM as a suitable approach for optimal parameters determination in soil washing for heavy metal remediation using shikakai.
Resultant peak dissection by match 3 in XRD of Mg doped ZnO nanoparticles
Authors: Saraswathi V. , Ramanathan R. , Ramasamy R.
Published: July 2022

Pure nanomaterials have limited applications, so to enhance the quality of the material, dopants play an important role in the application. It is important to find out whether the crystal structure of the dopant is rearranged or it preserves its crystal structure even after it is being doped in the pure material. Zinc Oxide has hexagonal structure and MgO has cubic structure. When Mg is doped in ZnO at various temperatures, MgO rearranges itself and it also has hexagonal structure in some cases and in other cases, it preserves or changes its crystal structure other than hexagonal structure represented as secondary peaks. Match 3 tool has been used for Mg doped ZnO at 500OC wherein MgO has rearranged itself into hexagonal structure and ZnO has rearranged itself into cubic structure. EDAX studies confirm that the synthesized material contains only Zn, O and Mg which confirm that the secondary peaks are due to structural interchange and not due to any other impurities.
Lomefloxacin loaded solid lipid nanoparticles gel for topical ocular therapy: Optimization, evaluation and ex vivo studies
Authors: Gautam Darsh , Chaurasia Himanshu , Singh Ranjit
Published: July 2022

The present study was conducted to develop a novel Lomefloxacin-loaded SLN gel to treat eye infections. Lomefloxacin-loaded solid lipid nanoparticles were prepared by the emulsification solvent evaporation method. Stearic acid was used as solid lipid and poloxamer 188 as surfactant. Optimization of nanoformulation was done by Box Behnken Design using Design Expert Software 12. Stearic acid, poloxamer 188 and propylene glycol concentrations were the independent variables and particle size and % entrapment efficiency (EE) were dependent variables. The optimized lomefloxacin-loaded SLN was further incorporated into Chitosan (LSNG). A total of 9 batches (LSNG1 to LSNG9) were prepared by varying the concentration of Chitosan from 0.05% w/v to 0.25%w/v. LSNG8 was selected as an optimized batch based on its gelling capacity and viscosity. In vitro and ex vivo studies of LSNG8 showed drug release for a prolonged period of time. Furthermore, the HET-CAM test revealed that the formulation is non-irritant and thus can be well tolerated when instilled in the eye. Therefore, LSNG8 can offer improved management of microbial growth.
Nanostructured materials for removal of organic and inorganic contaminants from water and wastewater
Authors: Ahmaruzzaman Md.
Published: July 2022

Nanomaterials with smaller size and larger surface area act as an excellent adsorbent for effective removal of various organic and inorganic pollutants from water and wastewater. Multi-walled carbon nanotubes were found to be the promising nanomaterials for purification of water. Nano-metals and nano-metal oxides have also been utilized to render pollutants/contaminants harmless in wastewater. Nanomaterials like nano zero-valent silver are bioactive, they can destroy bacteria and other pathogenic microorganisms and are an alternative to chlorine bleaches. Nanomaterials can also be used to detect the presence of virus in wastewater and can effectively remove them which cannot be removed by current techniques. Second generation nanomembranes are being designed to detect and remove various pollutants from water. However, precautions must be taken while using nanoparticles to avoid any threat to human health and environment. There is a high need to modify and synthesize nanoparticles with high efficiency, eco-friendly nature and less cost of production. In future, nanomaterials will become essential component for wastewater treatment because more and more progress is being made in the field of nanotechnology to upgrade nanomaterials in terms of economically efficient and ecofriendly technology.
pH Accelerates the Long-Range Electron Transfer for Lignin Degradation via Second-Sphere H-Bonding Interactions
Authors: Fang Wenhan , Feng Shishi , Jiang Zhihui , Liang WanZhen , Li Pengfei , Wang Binju
Published: July 2022

pH plays versatile roles in both biology and chemistry. For instance, pH can regulate the long-range electron transfer (ET) in many proteins. However, the mechanistic basis of many pH-dependent long-range ET processes remain unclear. In this study, we unravel the critical role of pH in accelerating the long-range ET in lignin peroxidase (LiP) using QM/MM MD simulations and the nonadiabatic ET and PCET theories. As a key enzyme involved in lignin degradation, LiP accomplishes the one-electron oxidation of lignin via two consecutive long-range ET reactions: the first one involves ET from Trp171 to the active species of Compound I, affording the Trp171 radical species, while the second one involves ET from the lignin substrate to the Trp171 radical, affording the lignin cation radical species. Our study demonstrates that pH can remarkably modulate the mechanism and kinetics of both ET reactions. Specifically, in the absence of the pH buffer of tartaric acid, our study shows that the first ET leads to a neutral Trp• radical, agreeing with the EPR experiments. Surprisingly, the addition of the tartaric acid stabilizes the Trp-H•+ cation radical via second-sphere H-bonding interactions and accelerates the ET rate for lignin oxidation by several orders of magnitude. These findings are consistent with the experimental information available, which not only expand our understanding on pH-dependent ET reactions in both biology and chemistry, but also provide valuable insights on tryptophan-mediated biological ET reactions.
Importance and Impact of International Agreements or Protocols to Protect Ozone and Beyond
Authors: Hazra Montu K. , Mondal Soumen , Sadhukhan Saikat
Published: July 2022

Synchronized control of both global warming and ozone depletion is prerequisite for the sustainable stability of our bio-diversity. Here we uncover the importance of Paris Agreement and Kyoto Protocol and the new impact of Montreal Protocol to protect stratospheric ozone by considering the prototype H₂O + O(¹D) → 2OH insertion/addition reaction as the representative reaction of potent GHG molecules with steady state O(¹D). While CO₂ via its continuous regeneration CO₂ + O(¹D) → CO₂ + O(³P) reaction in stratosphere is involved in ozone hole formation, the geoengineering via nonstop CaCO₃ injections in stratosphere in future would also be responsible for ozone hole formation. Moreover, the classical nature of single potential wells of single step exothermic barrierless reactions governed by quantum mechanics de-energizes the energized adducts or products analogous to energy conservation of a falling mass from some height under gravity and plays decisive role in the extent of pressure independency of rate constants.
Accurate determination of interfacial thermal resistance inside particle-laden composites based on high-throughput computation and machine learning
Authors: LU XIAOXIN , HUANG JIABIN , CHENG NAN , REN LINLIN , XU JIANBIN , LU JIBAO , SUN RONG
Published: July 2022

Particle-laden composites are typical thermal interfacial materials (TIMs) in the electronic applications, which are widely used in the electron packaging fields. The effective thermal conductivity (effective TC) of the particle-laden composites is dominant by the particle-matrix and particle-particle interfacial thermal resistance (ITR). The reliable identification of ITR is essential for the accurate prediction of TC of the composites, which has potential in the design of TIMs. In this work, we propose an efficient strategy to identify the interfacial thermal resistance in the particle-laden composites combining the numerical simulation, high-throughput computation, machine learning algorithm and simple experimental measurement. Firstly, the high-throughput computation is conducted based on the numerical modeling of the standard samples, in which the input parameters are ITRs in the composites. Afterwards, a prototypical function-based machine learning strategy is employed on the database to describe the numerical relation between the effective TC and the input parameters. Finally, comparing the numerical predictions from the machine learning model with the experimental measurement of the effective TC, a high-throughput screening of the ITRs is executed for the identification of their values. The reliability of the strategy is validated by an example of Al2O3-AlN/silicone composites, showing that the particle-particle ITR is higher than particle-matrix ITR.
A Novel Instrumented Technique for Measuring Cutting Resistance of Plastics : Comparison with Rodent Bite Resistance Test and Other Mechanical Properties of the Material
Authors: Praharaj Bhatnagar Manoj
Published: July 2022

This paper discusses a new mechanical test, to study the resilience of cutting of specimens, using a heavy-duty cable cutter, with an aim to mimic rodent damage of materials. Various mechanical properties of the composites; like tensile modulus, tensile strength, toughness and roughness have been studied, and corroborated with resilience and toughness of cutting. Performance of 3 compositions; consisting of certain Blends of Polyamide 12 : HDPE, Hytrel : Polytrimethylene Terephthalate (PTT), and Wollastonite reinforced Hytrel : HDPE Blends, selected from a pool of earlier studied blends and composites, displaying high Shore D and Scratch hardness, have been compared to the popular choice for cable jacketing i.e., High Density Polyethylene (HDPE). These 4 types of materials have also been exposed to rodents, to compare the results with the newly developed cutting test. These results help in understanding the properties that are essential in a material to prevent rodent damage.
Epistemic Trepassing and Expert Witness Testimony
Authors: Satta Mark
Published: July 2022

Epistemic trespassers have competence in one field but pass judgment on matters in other fields where they lack competence. I examine philosophical questions related to epistemic trespassing by expert witnesses in courtroom trials and argue for the following positions. Expert witnesses are required to avoid epistemic trespassing. When testifying as an expert witness, merely qualifying one’s statements to indicate that one is not speaking as an expert is insufficient to avoid epistemic trespassing. Judges, litigators, and jurors can often recognize epistemic trespassing by examining a purported expert’s credentials and track record. Judges should not permit recognizable epistemic trespassers to testify as expert witnesses. Litigators should seek to expose recognizable epistemic trespassers during cross-examination. Jurors should treat recognizable instances of epistemic trespassing as a reason to downgrade the testimony of epistemic trespassers.
Retrospective Analysis of 128 Patients of Acupuncture Consultation After Pancreatic Surgery
Authors: Chang Siyu , Niu Ru , Wang Ning , Du Guangzhong
Published: July 2022

Abstract?Objective: To analyze and summarie the the current situation of acupuncture consultation of postoperative patients for pancreatic caner in Qilu hospital of Shandong University and provide reference for acupuncture treatment of postoperative complications after pancreatic surgery.effect of acupuncture in treating gastrointestinal dysfunction after pancreatic surgery.Methods: Consultation reasons, diagnosis, treatments, patient compliance and effect of 128 cases from October 9,2020 to October 9,2021 was statistical analyzed. Result? A total of 128 patients were involved, 116 of those were completely treated. Effective rate of acupuncture for early postoperative inflammatory bowel obstruction was 94.85 % ?for postoperative gastric emptying dysfunction was 81.25% ? for early postoperative inflammatory bowel obstruction with gastric emptying disorder was 66.67 %and clinical total effective rate was 91.38 %.Conclusion: Acupuncture can promote pancreatic gastrointestinal function rehabilitation and provide new methods for enhanced recovery after surgery concept.
Clinical Effect of Imatinib, Nilotinib, and Dasatinib on Chronic Myeloid Leukemia in Chronic Phase
Authors: Miao Yudi
Published: July 2022

The study was conducted to explore the effect of imatinib, nilotinib, and dasatinib in the treatment of chronic myeloid leukemia (CML) patients. Around 66 patients with CML in chronic phase were selected, subsequently the patients were subdivided into 3 groups with 22 patients in each group: Group A were treated with imatinib; Group B were treated with nilotinib; and Group C were treated with dasatinib. The study showed that, at 18 months of treatment, compared with group A, the molecular biology remission rates of group B and group C were significantly higher, p<0.05; at 6 months and 18 months of treatment, compared with group A, the complete cytogenetic remission rates of group B and group C were significantly higher, p<0.05; and compared with group A, the incidences of vomiting, headache and edema in groups B and C were significantly lower, p<0.05. However, no significant different p>0.05 were observed in the complete hematologic remission rates, and the incidences of neutropenia and thrombocytopenia among the three groups. In summary, nilotinib and dasatinib are effective in the treatment of patients with CML in the chronic phase, which is significantly better than imatinib treatment.
The Application of “Humanized” Concept in Urban Road Design
Authors: Fu Mi
Published: July 2022

In order to promote the development of urban roads, enhance urban road design, and fully maximize the role of urban roads, this study first discusses the fundamental requirements of urban road design, the “humanized” concept in urban road design, and the importance of “humanized” urban road design, as well as proposes several “humanized” design strategies for urban roads as references.
环境工程中污水和废气处理工程研究分析
Authors: 欣 王 , 正伟 阮 , 晓霞 张
Published: July 2022

随着经济社会的快速发展，人们对于发展的要求越来越高，不仅要求其发展速度，还要求其发展质量，人们保护自然生态环境的意识也越来越高。在环境工程当中，污水以及废气的存在会严重影响到环境工程的质量，为了切实保障环境工程的质量，论文针对其污水和废气进行相关的研究分析，极大程度上降低污水和废气。
火电厂大气污染排放现状及烟气脱硫脱硝技术
Authors: 晓肖 刘
Published: July 2022

随着市场经济的稳健发展，中国经济水平的提升，对于煤炭能源的回收利用量也呈现加大的趋势，尤其是对于一些火电厂的企业来说，煤炭本身的使用和燃烧数量也呈现逐年递增的趋势，所排放的大量污染物质对于火电厂周边环境生态也产生了较大的污染影响，危害了人们的生产生活。为了加快对于火电厂大气污染问题的分析，加快对于环境保护工作的落实，就需要相关的技术人员在原有的火电厂大气污染排放综合管理的基础上，以烟气脱硫脱硝技术为基础进行工作任务反思，以便于加快环境保护工作的落实。因此，论文在火电厂大气污染排放现状研究分析的基础上，对烟气脱硫脱硝技术手段进行观察判断，以求推动火电厂综合防治管理工作的落实，提升环境综合治理质量。
中国新能源企业关于促进产业低碳化转型探究——基于 “碳达峰”与“碳中和”的视角
Authors: 琴 罗 , 雨达 刘 , 文婕 林
Published: July 2022

自工业化以来，全球地表温度一直处于上升趋势，已对全球生态系统、社会经济环境以及人类生活环境造成严重影响，在此背景下实现“双碳”目标势在必行。“双碳”政策的提出一方面使环保理念深入人心，刺激低碳产品需求，释放低碳企业发展潜力，引领企业加速绿色化、低碳化转型，为新能源企业进一步发展带来机遇。另一方面，由于技术转型难度大，投入产出比低，“双碳”政策为以制造业为代表的高耗能企业带来挑战。
中国城市污水处理的主要工艺及发展趋势
Authors: 超 张 , 丽霞 陶
Published: July 2022

众所周知中国是一个部分地区水资源严重短缺的国家，目前，随着现代化进程的逐步加快，社会基础设施的发展越来越完善，社会产业的规模越来越大。工业发展的同时容易带来环境问题，生产工作消耗水源、排出污水，将给周边的生态带来严峻的考验。对此，如何解决水资源紧缺问题并且处理好污水问题成为社会各界积极探究的重点问题。论文从中国污水处理现状出发，对中国污水处理发展趋势进行分析，为环境保护工作以及生态建设工作提供发展思路。
探讨环境监测与环境影响评价的关系
Authors: 炜 季
Published: July 2022

近些年来，中国越来越注重环境监测和保护工作，要求各行业以保护生态环境为前提已经发展，但是在这一过程中也存在不少对环境破坏污染等的案例，因此采取了环境监测与环境影响评价工作。通过落实两项工作，能够了解环境的实际情况，获得正确数据，开展全面评价，为环境保护治理等提供依据。在论文的研究工作中主要分析了环境监测与环境影响评价的主要内容，重点探讨两者的关系，分析工作中的问题，提出几点有效的对策，以及提高环境监测与环境影响评价的质量。
建设项目竣工环保验收中常见不足及优化措施
Authors: 春艳 王 , 伟杰 欧
Published: July 2022

近年来，中国经济发展的速度越来越快，经济的快速发展带来的环境污染问题日益突出，迫切需要通过各种有效措施加强环境保护，有效改善生态环境的质量，从而实现经济的可持续发展。建设项目竣工环保验收是加强环境保护工作中的重要内容。目前，中国建设项目竣工环保验收工作还存在着一定的问题，相关工作者需要深入分析这些问题，然后提出具体的优化措施，使得存在的问题得到有效的解决，从而提高建设项目竣工环保验收工作的质量，为环境保护工作作出更多的贡献。
Auch Justitia dichtet. Zur Konstruktion des Verbrechens in der Geschichte des Marquis de la Pivardiere
Authors: Speth Sebastian
Published: July 2022

Am Beispiel der Pitavalgeschichte des Marquis de la Pivardiere ist der Beitrag der asymmetrischen Verhorsituation im Inquisitionsverfahren gewidmet1. Untersuchungsrichter und Protokollant verdichten die Aussagen der Magde des Marquis zu einer juristisch belastbaren Erzahlung des Tathergangs. Gezeigt wird, wie sich in der Fassungsgeschichte (Gayot de Pitaval, Friedrich Schiller, Neuer Pitaval) der Wandel zum reformierten Strafprozess spiegelt. Der in den Akten dokumentierte Manipulationsvorwurf dient bei Gayot zur Mahnung an eine formstrenge Durchfuhrung des Verfahrens, wahrend Schiller darin einen anthropologisch verwertbaren Einblick in die Psyche des Tatersubjekts erkennt. Der neue Pitaval disqualifiziert das Inquisitionsverfahren im Ganzen, um ihm die preu.ische Rechtspraxis entgegen zu stellen.
Zum Verhältnis von Geist und Gegenstand als Gradmesser einer inneren Entwicklung in Wielands "Geschichte des Agathon"
Authors: Janca Timo
Published: July 2022

In Christoph Martin Wielands Geschichte des Agathon (Erste Fassung 1766/67) durchlauft der Protagonist einen inneren Reifeprozess, wobei das Verhaltnis innerlicher Erkenntnis im Wechselspiel mit der Objektwelt im Zentrum steht. Der nachfolgende Artikel bringt den Werdegang in Zusammenhang mit der philosophischen Debatte zwischen Idealismus und Realismus sowie der versuchten Versohnung beider Positionen durch Immanuel Kant. Auf dieser Grundlage sollen Agathons zwischenmenschliche Begegnungen von Pytia bis Danae uberpruft wie auch als Gradmesser seiner inneren Reifung betrachtet werden.
Empfindsam glückselig – Zur Bedeutung der Glückseligkeit in der Epoche der Empfindsamkeit am Beispiel von Sophie von La Roches "Geschichte des Fräuleins von Sternheim"
Authors: Dingelmaier Theresia
Published: July 2022

Der Beitrag beschaftigt sich ausgehend von Goethes Die Leiden des jungen Werthers mit dem Gefuhl der Gluckseligkeit in der Literatur der Aufklarung und Empfindsamkeit am Beispiel von Sophie von La Roches Die Geschichte des Fräuleins von Sternheim und damit dem unmittelbaren Vorfeld der Zeit um 1800. Unter Ruckgriff auf eudaimonie-Konzeptionen der Antike und der Fruhen Neuzeit sollen die Gluckseligkeit bzw. literarische Darstellungen, die als Medium der Erkundung und Herstellung menschlicher Gluckseligkeit – und damit auch der Annaherung an die Innenwelt des Menschen – fungieren, analysiert und vorgestellt werden. Die These ist, dass im Lichte einer verstarkt der ‚gluckseligen Innerlichkeit’ der Protagonist*innen zugewandten literaturwissenschaftlichen Untersuchung neue Erkenntnisse uber die Literaturepoche Empfindsamkeit und damit auch das angestrebte Gefuhlsleben der Zeit vor 1800 zutage treten.
Inszenierte Kindheit. Selbsttherapien und Körperdiskurs im Roman "Anton Reiser" von Karl Philipp Moritz
Authors: Haas Agnieszka K.
Published: July 2022

Der vorliegende Aufsatz untersucht den ersten Teil des Romans Anton Reiser (1785–1790) von Karl Philipp Moritz in Bezug auf den Melancholie- und Körperdiskurs in ihrem Zusammenhang mit dem Bücherwahn, der hier nicht als Ursache des Scheiterns, sondern als Selbsttherapie und Bekämpfungsmittel der Melancholie in der Kindheit betrachtet wird. Im Vordergrund stehen die ersten Kinderjahre Anton Reisers und seine frühen Textlektüren. Im Beitrag wird der Frage nachgegangen, ob die Bücherlektüre als intertextuell verankerter Autotherapieversuch und Kompensation von Bedürfnissen angesehen werden kann. Dabei werden die Methoden des Umgangs mit eigener Emotionalität im Roman überprüft.
Wer blind wählet – Eine Jungsche Lektüre von Goethes "Die Wahlverwandtschaften"
Authors: Ferro Milone Giulia
Published: July 2022

Was passiert eigentlich in Goethes Roman Die Wahlverwandtschaften? Was passiert, wenn die Individuen von unbewussten Prozessen wie denjenigen, die sich in der Metapher der chemischen Affinitäten verstecken, überwältigt werden? Der vorliegende Beitrag möchte sich mit diesen Fragen aus tiefenpsychologischer Perspektive befassen und aufzeigen, dass Goethe in seinem Roman sich sehr nah an einem Konzept des Unbewussten und der Psyche positioniert, wie es Carl Gustav Jung etwa hundert Jahre später konzipiert hat. Die Individuen, die als Gefangene einer rigiden Lebenseinstellung unbewusst (blind) wählen, sind nicht imstande wahre Entscheidungen zu treffen und für sie bleibt das Leben letzten Endes ein Rätsel.