bluuebunny/crossref_metadata_2025 huggingface dataset:
Extracellular DNA NET-Works With Dire Consequences for Health
Authors: Sorvillo Nicoletta , Cherpokova Deya , Martinod Kimberly , Wagner Denisa D.
Published: August 2019

Neutrophils play a central role in innate immune defense. Advances in neutrophil biology have brought to light the capacity of neutrophils to release their decondensed chromatin and form large extracellular DNA networks called neutrophil extracellular traps (NETs). NETs are produced in response to many infectious and noninfectious stimuli and, together with fibrin, block the invasion of pathogens. However, their formation in inflamed blood vessels produces a scaffold that supports thrombosis, generates neo-antigens favoring autoimmunity, and aggravates damage in ischemia/reperfusion injury. NET formation can also be induced by cancer and promotes tumor progression. Formation of NETs within organs can be immediately detrimental, such as in lung alveoli, where they affect respiration, or they can be harmful over longer periods of time. For example, NETs initiate excessive deposition of collagen, resulting in fibrosis, thus likely contributing to heart failure. Here, we summarize the latest knowledge on NET generation and discuss how excessive NET formation mediates propagation of thrombosis and inflammation and, thereby, contributes to various diseases. There are many ways in which NET formation could be averted or NETs neutralized to prevent their detrimental consequences, and we will provide an overview of these possibilities.
Racial and Ethnic Disparities in the Utilization of Thrombectomy for Acute Stroke
Authors: Rinaldo Lorenzo , Rabinstein Alejandro A. , Cloft Harry , Knudsen John M. , Castilla Leonardo Rangel , Brinjikji Waleed
Published: August 2019

Background and Purpose—

Racial and ethnic disparities in the access to mechanical thrombectomy (MT) for treatment of acute ischemic stroke (AIS) secondary to large vessel occlusion have been previously described. The effect of recent randomized trials validating MT as an effective therapy for AIS secondary to large vessel occlusion on such disparities has not been investigated.

Methods—

Information on admissions for AIS to endovascular centers occurring between January 2016 and September 2018 was obtained from a national database. The number of patients receiving IV-tPA (intravenous tissue-type plasminogen activator) and MT at each institution was determined, and patient demographics were characterized according to age, sex, race/ethnicity, and insurance status. Comparisons of patients who did and did not undergo MT and between patients of different racial and ethnic backgrounds were performed. Demographic variables independently associated with the utilization of MT were identified using multivariate linear regression analysis.

Results—

There were 206 853 admissions to 173 endovascular centers during the time period of interest. The overall utilization of MT was 8.4%. The utilization of MT for black/Hispanic patients was lower than that among white/non-Hispanic patients (7.0% versus 9.8%;
P
<0.001). Black/Hispanic patients were also less likely to receive IV-tPA (16.2% versus 20.5%;
P
<0.001) and to be admitted to the endovascular center after transfer from a different hospital (20.0% versus 30.1%;
P
<0.001). On multivariate linear regression analysis, increasing institutional proportions of patients with female sex (β=−0.601;
P
<0.001), insurance with Medicaid or uninsured status (β=−0.153;
P
=0.029), and black/Hispanic race/ethnicity (β=−0.062;
P
=0.046) were independently associated with lower institutional utilization of MT.

Conclusions—

Despite the mainstream acceptance of MT for the treatment of AIS secondary to large vessel occlusion, racial and ethnic disparities in the utilization of MT persist.
Cochlear-Vestibular Impairment due to West Nile Virus Infection
Authors: Parrino Daniela , Brescia Giuseppe , Trimarchi Maria Vittoria , Tealdo Giulia , Sasset Lolita , Cattelan Anna Maria , Bovo Roberto , Marioni Gino
Published: August 2019

Objectives:

West Nile virus (WNV) has been spreading over the last 20 years. Human infection is asymptomatic in most cases. When the disease becomes clinically manifest, it may involve a range of issues, from a mild infection with flu-like symptoms to a neuroinvasive disease. Albeit rarely, WNV-associated sensorineural hearing loss (SNHL) has also been reported. Here we describe two new cases of SNHL and balance impairment caused by WNV infection.

Methods:

The patients were investigated with repeated audiometric tests and, for the first time, videonystagmography was also used.

Results:

Unlike findings in the few other published cases, an improvement in audiometric thresholds and vestibular function was documented in both of our patients.

Conclusions:

In the light of our findings, a prospective study would be warranted on a large series of patients with WNV infection in order: (i) to better define the epidemiology of the related cochlear-vestibular involvement; and (ii) to elucidate the virus-related changes to peripheral and central auditory and vestibular functions.
The Real Meaning of “Managed Care”: Adaptive Accumulation and U.S. Health Care
Authors: Loeppky Rodney
Published: August 2019

The boundaries of what constitutes “sufficient” health have always been open and, as such, health care has proven to be an opportune area for profit growth. In the United States, the allure of health as a market commodity has proven very strong, but even here it cannot be a mere spontaneous product of the market. It requires government to foster and develop public policy that effectively promotes and maintains health care delivery across the population. Historically, U.S. public policy has veered away from anything akin to universal care, and it has typically been understood as an outlier among advanced industrial states. But, simultaneously, it is also the largest health care market in the world, soon to engulf a full fifth of its GDP. In this paper, I argue that the complicated dynamic between a growing market in health delivery and a patchwork of political reforms has encouraged “adaptive accumulation,” a process whereby capital secures optimized accumulation outcomes from enhanced government intervention, deriving extra-market benefits along the way. To make this argument, I explore critical components of the health system, including Medicare Advantage, Medicare Part D, as well as the Affordable Care Act and its aftermath.
Unravelling Hidden Informal Employment in Chile: Towards a New Classification and Measurements to Study Its Public Health Impact
Authors: Ruiz Marisol E. , Vives Alejandra , Puig-Barrachina Vanessa , Benach Joan
Published: August 2019

This study aims to assess differences in the working population of Chile under the definition of informal employment. A new categorization of informal employment is proposed, with a focus on social protection as a key element in the definition of informal employment status, thereby making visible different groups of workers that until now remained hidden. From a mixed methodological strategy that combines literature review, key informant interviews, and quantitative data analysis, the researchers seek to understand the complexity of the social phenomenon of informality.
Oral Diseases Associated with Nonalcoholic Fatty Liver Disease in the United States
Authors: Weintraub J.A. , Lopez Mitnik G. , Dye B.A.
Published: August 2019

The US prevalence of nonalcoholic fatty liver disease (NAFLD) is 30.6% and increasing. NAFLD shares some risk factors with periodontitis and dental caries. We explored the association between NAFLD and several oral conditions among US adults, using data from the cross-sectional, nationally representative National Health and Nutrition Examination Survey (NHANES), 1988 to 1994. NAFLD was assessed with ultrasonography (USON), the screening gold standard not available in the more recent NHANES, and the noninvasive Fibrosis Score (FS), Fatty Liver Index (FLI), and US Fatty Liver Index (US-FLI) as other screening alternatives. There were 5,421 eligible dentate adults aged 21 to 74 y with complete relevant data, with transferrin levels ≤50%, without hepatitis B or C, who were not heavy drinkers. Multivariable models were developed to examine the independent effects of moderate-severe periodontitis, untreated dental caries, caries experience, and tooth loss (<20 teeth) on NAFLD while controlling for clinical, biological, and sociodemographic factors. Weighted estimates for odds ratios (ORs) and 95% CIs were calculated with logistic regression. Between 17% and 24% of adults had NAFLD depending on the classification criteria. In adjusted models, as compared with those with better oral health, adults with <20 teeth were more likely to have NAFLD depending on the measure (USON: OR = 1.50, 95% CI = 1.11 to 2.02; FS: OR = 4.36, 95% CI = 3.47 to 5.49; FLI: OR = 1.99, 95% CI = 1.52 to 2.59; US-FLI: OR = 2.32, 95% CI = 1.79 to 3.01). People with moderate-severe periodontitis were more likely to have NAFLD (USON: OR = 1.54, 95% CI = 1.06 to 2.24; FS: OR = 3.10, 95% CI = 2.31 to 4.17; FLI: OR = 1.61, 95% CI = 1.13 to 2.28; US-FLI: OR = 2.21, 95% CI = 1.64 to 2.98). People with any untreated caries were more likely to have NAFLD (USON: OR = 1.51, 95% CI = 1.20 to 1.90; FLI: OR = 1.80, 95% CI = 1.33 to 2.44). NAFLD was associated with tooth loss, periodontitis, and, for some NAFLD measures, untreated dental caries but not overall caries experience after controlling for several key sociodemographic and behavioral factors. Results suggest that further evaluation is needed to better understand this health–oral health interrelationship and potential opportunities for medical-dental integration.
An objective and automated method for evaluating abdominal hyperalgesia in a rat model for endometriosis
Authors: van Aken Mieke AW , Groothuis Patrick G , Panagiotou Maria , Duin Marcel van , Nap Annemiek W , van Rijn Tineke CM , Kozicz Tamas , Braat Didi DM , Peeters Ard BWMM
Published: August 2019

Chronic pain and subfertility are the main symptoms of concern in women with endometriosis. In order to find new therapeutic options to suppress the pain, translational animal models are indispensable. We have developed a new automated, experimental setup, with full consideration for animal wellbeing, to determine whether operant behaviour can reveal abdominal hyperalgesia in rats with surgically-induced endometriosis, in order to assess whether abdominal hyperalgesia affect behavioural parameters. Endometriosis was induced by transplantation of uterine fragments in the abdominal cavity. Control groups consisted of sham-operated rats and non-operated rats. We have developed an operant chamber (Skinnerbox) which includes a barrier. The rat can climb the barrier in order to reach the food pellet, increasing in this way the pressure to the abdomen. We show that endometriosis rats collect significantly less sugar pellets when compared with the control rats after the introduction of the barrier. In the Skinnerbox experiment, we showed that in a positive operant setting, the introduction of a barrier results in a contrast of operant behaviour of endometriosis rats and control groups, perchance as a result of abdominal discomfort/hyperalgesia due to surgically-induced endometriosis. This is a promising start for the further development of a refined animal model to monitor abdominal discomfort/hyperalgesia in rats with surgically-induced endometriosis.
Let’s Start With the End: Bibliodrama in an Italian Death Education Course on Managing Fear of Death, Fantasy-Proneness, and Alexithymia With a Mixed-Method Analysis
Authors: Testoni Ines , Biancalani Gianmarco , Ronconi Lucia , Varani Silvia
Published: August 2019

This article presents the results of an experience of death education (DE) course with bibliodrama in Italian high schools, which focused on emotions and existential themes. The research analyzed the inability to recognize or describe one’s own emotions (alexithymia), fantasy-proneness, and attitudes toward death in two different groups of students: one who took a course on DE (with 113 students) and another who did not participate in it (with 114 students). The use of a mixed method allowed this study to explore the quantitative results that the students indicated in the questionnaire and the qualitative open answers to the final question about how they had profited from this DE course. The results showed that the course had a positive effect, as the DE group significantly decreased alexithymia and negative attitudes toward death, particularly in fear and avoidance of death, making their representation of death less traumatic.
Tracing Adolescent Girls' Motivation Longitudinally: From FitClub Participation to Leisure-Time Physical Activity
Authors: Laroche Julie-Anne , Girard Stephanie , Lemoyne Jean
Published: August 2019

Scientific evidence reveals a significant decline in exercise behaviors during adolescence. Although multiple school-based initiatives have been implemented in Canada, little is known of how these initiatives affect students' motivation for subsequent physical activity (PA). The transcontextual model of motivation offers an interesting approach to assessing the long-term, motivational impact of school-based interventions, and we used this model to study how adolescent girls' need satisfactions, first observed within supervised PA (in the FitSpirit FitClub), correlated with their inclinations toward nonsupervised PA behaviors later. Adolescent girls in this study ( N = 259; M = 14.34, SD =  1.49 years) completed a transcontextual model of motivation-based questionnaire regarding their basic psychological needs, motivation, attitudes, subjective norms, perceived behavioral control, intentions, and PA practice during their FitSpirit club participation. Three weeks after this participation, they reported their PA levels again. The girls' basic psychological needs predicted their autonomous motivation in the FitClub. Their autonomous motivation predicted subjective norms and perceived behavioral control; these factors then determined their intentions to be physically active, and their PA intentions predicted their actual PA behavior during personal (leisure) time three weeks later. Two indirect paths were statistically significant for predicting PA intentions, and three indirect paths were significant for predicting leisure-time PA. Activity motivation, first developed within a supervised context, can increase subsequent leisure-time PA.
Book review: Vishwa Anand, Poverty & Rural Violence in Bihar: A Sociological Analysis
Authors: Thakur Manish
Published: August 2019

Vishwa Anand, Poverty & Rural Violence in Bihar: A Sociological Analysis. Delhi: Manak Publications Pvt. Ltd, 2017, 207 pp., ₹495 (Hardback).ISBN: 978-93-7831-449-0.
Towards a Sociological Understanding of Sexting as a Social Practice: A Case Study of University Undergraduate Men
Authors: Roberts Steven , Ravn Signe
Published: August 2019

This article makes the case for understanding young people’s engagement with ‘sexting’ as a social practice. Moving away from the dominant focus on teenagers and (sexual) risk and instead approaching sexting as an ‘everyday’ practice sheds light on how sexting is perceived and situated as a normalised part of contemporary youth culture. Drawing on 10 focus groups with 37 undergraduate men in Melbourne, Australia, our data reveal young men’s significant emphasis on consent, mutuality and respect, marking out ‘appropriate sexting’ practices as distinct from harassment or image-based abuse. Nonetheless, the centrality of a transactional approach to sexting questions those seemingly positive dispositions. Social practice theory permits sophisticated understanding of these nuances, seeing them as bound up and produced in correspondence with the broader meanings, embodied skills and material artefacts that are associated with sexting.
Wounds: Militarized nursing, feminist curiosity, and unending war
Authors: Enloe Cynthia
Published: August 2019

Taking wartime nurses – and post-war nursing – seriously makes one think more politically about the wounds endured in wartime and what counts as a wartime ‘wound’. Thinking about wounds and the wounded, in turn, reveals how war-waging officials, and militarizers more generally, have tried in the past, and today still try, to shrink citizens’ awareness of militarism’s negative consequences. Nursing, nurses, wounds, and the wounded each continues to be gendered, influencing the workings of both masculinities and femininities in past and current wartimes and post-war politics. Feminist analysts have expanded the ‘political’ and multiplied ‘political thinkers’. Failing to absorb these feminist theoretical insights fosters the trivialization of nurses and other caretakers of the wartime wounded and their diverse political thinking. It is a failing with serious implications. Overlooking nurses and others who provide wartime care, combined with a lack of curiosity about wounds, perpetuates militarization and war.
Gift versus Trade: On the Culture of Science Communication
Authors: Kasavin Ilya
Published: August 2019

This article aims at a critical reevaluation of the trading zone concept (Galison). It starts from a case study of the Faraday–Whewell collaboration in coming to terms with electrolysis experiments. The case is supposed to be an example of a trade zone of science/philosophy interaction though it demonstrates the unequal nature of the “trade.” This requires the analysis to log in some details concerning Galison’s metaphor of trading zones, which reveals its market-oriented connotations. The following criticism of the market metaphor for science applies a revised version of Boris Hessen’s argument (“commodity fetishism”) against misinterpretation of technology by some British scientists. A closer look at the ancient trade rituals in Marcel Mauss’ seminal work enables discovering another cultural pattern for describing scientific communication as opposed to trade—gift. This helps picture science as a distribution of social roles and statuses and uncovers the normative and value dimension of gift zones language.
Single-image Bayesian Restoration and Multi-image Super-resolution Restoration for B-mode Ultrasound Using an Accurate System Model Involving Correlated Nature of the Speckle Noise
Authors: Cüneyitoğlu Özkul Mine , Mumcuoğlu Ünal Erkan , Sancak İbrahim Tanzer
Published: August 2019

B-mode ultrasound is an essential part of radiological examinations due to its low cost, safety, and portability, but has the drawbacks of the speckle noise and output of most systems is two-dimensional (2D) cross sections. Image restoration techniques, using mathematical models for image degradation and noise, can be used to boost resolution (deconvolution) as well as to reduce the speckle. In this study, new single-image Bayesian restoration (BR) and multi-image super-resolution restoration (BSRR) methods are proposed for in-plane B-mode ultrasound images. The spatially correlated nature of the speckle was modeled, allowing for examination of two different models for BR and BSRR for uncorrelated Gaussian (BR-UG, BSRR-UG) and correlated Gaussian (BR-CG, BSRR-CG). The performances of these models were compared with common image restoration methods (Wiener filter, bilateral filtering, and anisotropic diffusion). Well-recognized metrics (peak signal-to-noise ratio, contrast-to-noise ratio, and normalized information density) were used for algorithm free-parameter estimation and objective evaluations. The methods were tested using superficial tissue (2D scan data collected from volunteers, tissue-mimicking resolutions, and breast phantoms). Improvement in image quality was assessed by experts using visual grading analysis. In general, BSRR-CG performed better than all other methods. A potential downside of BSRR-CG is increased computation time, which can be addressed by the use of high-performance graphics processing units (GPUs).
Cyanoacrylate closure for peripheral veins: Consensus document of the Australasian College of Phlebology
Authors: Parsi Kurosh , Roberts Stefania , Kang Mina , Benson Stephen , Baker Luke , Berman Ivor , Bester Lourens J , Connor David E , Dinnen Paul , Grace Joseph , Stirling Andrew , Ibrahim Nabeel , Lekich Christopher , Lim Adrian , Matar Luke , Nadkarni Sanjay , Paraskevas Peter , Rogan Christopher , Thibault Paul K , Thibault Simon , van Rij Andre , Yang Anes
Published: August 2019

Background

Cyanoacrylates are fast-acting adhesives used in procedural medicine including closure of superficial wounds, embolization of truncal vessels pre-operatively, vascular anomalies, visceral false aneurysms, endoleaks, gastrointestinal varices and gastrointestinal bleeding. More recently, catheter-directed cyanoacrylate adhesive closure was introduced as an alternative to endovenous thermal ablation (ETA) to occlude superficial veins of the lower limbs.

Objectives

To formulate policies for the safe and effective delivery of cyanoacrylate adhesive closure procedures in Australasia, based on current experience and evidence.

Methods

A panel of phlebologists including vascular surgeons, interventional radiologists, dermatologists and research scientists systematically reviewed the available data on cyanoacrylate products used in medicine and shared personal experience with the procedure. The reviewed material included bibliographic and biomedical data, material safety data sheets and data requested and received from manufacturers. Results and recommendations: Cyanoacrylate adhesive closure appears to be an effective treatment for saphenous reflux with occlusion rates at 36 months of 90–95%. We recommend a maximum dose of 10 mL of cyanoacrylate per treatment session. Serious complications are rare, but significant. Hypersensitivity to acrylates is reported in 2.4% of the population and is an important absolute contraindication to cyanoacrylate adhesive closure. 1 Post-procedural inflammatory reactions, including hypersensitivity-type phlebitis, occur in 10–20% of patients. 2 In the long term, cyanoacrylate adhesive closure results in foreign-body granuloma formation within 2–12 months of the procedure. We recommend against the use of cyanoacrylate adhesive closure in patients with uncontrolled inflammatory, autoimmune or granulomatous disorders (e.g. sarcoidosis). Caution should be exercised in patients with significant active systemic disease or infection and alternative therapies such as thermal ablation and foam sclerotherapy should be considered.

Conclusions

Cyanoacrylate adhesive closure appears to be an effective endovenous procedure, with short-term closure rates comparable to ETA and therefore greater efficacy than traditional surgery for treating superficial veins of the lower limbs. Ongoing data collection is required to establish the long-term safety.
Hospitalizations of nursing home residents at the end of life: A systematic review
Authors: Allers Katharina , Hoffmann Falk , Schnakenberg Rieke
Published: August 2019

Background:

End-of-life hospitalizations in nursing home residents are common, although they are often burdensome and potentially avoidable.

Aim:

We aimed to summarize the existing evidence on end-of-life hospitalizations in nursing home residents.

Design:

Systematic review (PROSPERO registration number CRD42017072276).

Data sources:

A systematic literature search was carried out in PubMed, CINAHL, and Scopus (date of search 9 April 2019). Studies were included if they reported proportions of in-hospital deaths or hospitalizations of nursing home residents in the last month of life. Two authors independently selected studies, extracted data, and assessed the quality of studies. Median with interquartile range was used to summarize proportions.

Results:

A total of 35 studies were identified, more than half of which were from the United States ( n = 18). While 29 studies reported in-hospital deaths, 12 studies examined hospitalizations during the last month of life. The proportion of in-hospital deaths varied markedly between 5.9% and 77.1%, with an overall median of 22.6% (interquartile range: 16.3%–29.5%). The proportion of residents being hospitalized during the last month of life ranged from 25.5% to 69.7%, and the median was 33.2% (interquartile range: 30.8%–38.4%). Most studies investigating the influence of age found that younger age was associated with a higher likelihood of end-of-life hospitalization. Four studies assessed trends over time, showing heterogeneous findings.

Conclusion:

There is a wide variation in end-of-life hospitalizations, even between studies from the same country. Overall, such hospitalizations are common among nursing home residents, which indicates that interventions tailored to each specific health care system are needed to improve end-of-life care.
Use of time in people with a life-limiting illness: A longitudinal cohort feasibility pilot study
Authors: Jones Terry A , Olds Timothy S , Currow David C , Williams Marie T
Published: August 2019

Background:

To date, time-use studies in palliative care have been limited to exploration of time commitments of caregivers. Understanding time-use in people with a life-limiting illness might provide insight into disease progression, symptom management and quality of life.

Aim:

To determine the feasibility of a repeated-measures, time-use study in people with a life-limiting illness, and their primary caregivers, and to explore associations between time-use and perceived quality of life.

Design:

An observational repeated-measures feasibility pilot study. A priori criteria were established for study uptake (70%), retention (80%) and study value/burden (⩾7 Numerical Rating Scale 0–10). Burden and value of the study, use of time (Multimedia Activity Recall for Children and Adults with adjunctive accelerometry) and quality of life data (EuroQol-5 Dimension-5-Level Health Questionnaire and Australia-modified Karnofsky Performance Status scale) were assessed at time-points across five consecutive months.

Setting/participants:

People living with a life-limiting illness and caregivers recruited from Southern Adelaide Palliative Services outpatient clinics.

Results:

A total of 10 participants (2 caregivers and 8 people with a life-limiting illness) enrolled in the study. All but one of the criteria thresholds was met: 66% of participants who consented to be screened were enrolled in the study, 80% of enrolled participants ( n = 8) completed all assessments (two participants died during the study) and mean Numerical Rating Scale scores for acceptable burden and value of the study exceeded the criteria thresholds at every time-point.

Conclusion:

A repeated-measures time-use study design is feasible and was not unduly burdensome for caregivers and people living with a life-limiting illness.
Carbapenem-resistant Pseudomonas aeruginosa and carbapenem use in Japan: an ecological study
Authors: Terahara Fumitaka , Nishiura Hiroshi
Published: August 2019

Objective

This study focused on carbapenem resistance in Pseudomonas aeruginosa and examined potential ecological correlations with carbapenem use in Japan.

Methods

The proportion of carbapenem-resistant P. aeruginosa isolates from 2015 and 2016 by prefecture was obtained from the Japan Nosocomial Infections Surveillance system. Data on carbapenem use was obtained from the National Database of Health Insurance Claims. The correlation between the proportion of carbapenem-resistant isolates and carbapenem consumption was assessed in a cross-sectional manner. The study also collected information on other variables including the numbers of physicians, nurses and medical facilities per 100 000 individuals by prefecture.

Results

Both the proportion of carbapenem-resistant P. aeruginosa isolates and levels of carbapenem use were higher in western Japan. Using a multivariate model, only carbapenem use remained significantly associated with the proportion of carbapenem-resistant isolates.

Conclusions

Carbapenem use and the proportion of carbapenem-resistant P. aeruginosa isolates were positively correlated. By longitudinal data collection, this approach offers an avenue to establish causal links as the frequency of carbapenem-resistant P. aeruginosa isolates starts to change in the future.
Three-dimensional adhesion failure analysis of the single lap joint having pre-embedded circular defects
Authors: Behera Ranjan K , Parida SK , Das RR
Published: August 2019

The present research aims to study the growth of the circular adhesion failure pre-existing at the interfaces of the strap adherend and the adhesive in a single lap joint. Three-dimensional nonlinear finite element analysis of adhesively bonded single lap joints made with high strength steel adherends under uniformly applied extension have been carried out. The interfacial stresses and strain energy release rate values, being indicative parameters, in the growth of the adhesion failures are computed in the vicinity of the pre-existing circular adhesion failure fronts when the load on single lap joint increases till failure. The magnitudes of the strain energy release rate are computed using the virtual crack closure technique. The results show that the sizes of the adhesion failure significantly influence the magnitudes of the interfacial stresses, the three modes of strain energy release rates and the load-bearing capacity of the single lap joint. The finite element analysis predicts that pre-embedded circular adhesion failures will not have grown from the pre-embedded circular adhesion failure front, instead the failure will be initiated from the overlap ends upon loading for the adhesive bonded single lap joint made with strong adherends and AV119 adhesive. The finite element analysis also proposes a method to calculate the strength of this type of joint configurations using the global shear strength of the adhesive and the intact bonded area. The finite element analysis predicted failure strength of the single lap joint is in good agreement with the experimentally obtained strength for the single lap joint containing pre-existing circular adhesion failure.
‘An Unnatural Crime’: Infanticide in Early Nineteenth-Century Ireland
Authors: Kelly James
Published: August 2019

Infanticide reached record levels in Ireland in the mid-nineteenth century. Although the rising population and increasing poverty provided the essential precondition for this, the sharp rise in the practice identified by contemporaries in the 1820s and 1830s might not have taken place had the Dublin and Cork Foundling Hospitals continued to assume responsibility for the care of foundling children. But once they were no longer available to receive them, the women who give birth to the children that society identified as illegitimate chose to terminate their lives in record numbers in an attempt to avoid the severe stigma that this brought and the practical difficulties of taking care of a child alone. Using the cases that came before the coroners court and the crime figures assembled by the Royal Irish Constabulary from the 1830s, this article combines the quantitative analysis of the practice that this permits with a reliance on the qualitative approach that informed a previous investigation of the phenomenon in the eighteenth century to track its evolving trajectory, to identify its main features and to explain how it had arrived at a point by the 1840s when it exceeded homicide as the primary cause of violent death.
More Practical Wheel Tracking Test for Rutting Resistance of Asphalt Mixtures
Authors: Lemke Zachary , Bahia Hussain U.
Published: August 2019

Wheel tracking tests have seen a vast increase in usage among various state department of transportations for measuring rutting resistance of mixtures that already meet volumetric property requirements. With the increase in using recycled materials and warm mix additives, it is clear that using volumetric properties alone to approve asphalt mixture designs is a risky approach. Wheel tracking tests are among the most widely used methods for evaluating rutting resistance, and the AASHTO T324 (Hamburg Wheel-Tracking [HWT]) is the most widely accepted and followed procedure used today in the U.S. However, there are challenges using the HWT, among which the most difficult are the poor repeatability, time required to complete the test, and the sample preparation details. This study reports on an alternative wheel tracking method called the Rotary Asphalt Wheel Tester (RWT) that can successfully address the challenges currently faced with using the HWT. The method requires no cutting of the gyratory samples, significantly reduces time to complete a sample, and appears to offer acceptable repeatability of the results. The method has existed for more than 15 years, available commercially, but used only in a few labs, and one acceptance criterion is already developed by one agency. The study includes evaluating an expanded set of mixtures tested at two temperatures, and two air voids. The results of the RWT are compared with the results of the HWT for numerous mixtures and they show that similar qualitative ranking can be achieved.
The Deficit Profile of Elementary Students With Computational Difficulties Versus Word Problem-Solving Difficulties
Authors: Lin Xin , Peng Peng , Luo Hongjing
Published: August 2019

The purpose of the study was to compare the deficit profiles of two important types of mathematics difficulties. Three cognitive measures (working memory, processing speed, and reasoning), two mathematics measures (numerical facts retrieval and mathematics vocabulary), and reading comprehension were assessed among 237 Chinese fourth-grade students, among whom 28 were classified as students with only computational difficulties (CD), 34 were classified as having only word problem-solving difficulties (WPD), 20 were classified as students with computational and word problem-solving difficulties (CD + WPD), and 43 typically developing (TD) peers. Multivariate analysis showed that, compared with TD, CD was associated with weakness in numerical working memory; WPD was associated with weakness in reading comprehension; both CD and WPD were associated with weakness in mathematics vocabulary. However, CD and WPD did not differ from each other on any of those profiling measures. Implications for understanding mathematics competence and identification of mathematics difficulties are discussed.
The many lives of state capitalism: From classical Marxism to free-market advocacy
Authors: Sperber Nathan
Published: August 2019

State capitalism has recently come to the fore as a transversal research object in the social sciences. Renewed interest in the notion is evident across several disciplines, in scholarship addressing government interventionism in economic life in major developing countries. This emergent field of study on state capitalism, however, consistently bypasses the remarkable conceptual trajectory of the notion from the end of the 19th century to the present. This article proposes an intellectual-historical survey of state capitalism’s many lives across different ensembles of writing: early Marxist pronouncements on state capitalism at the time of the Second International; theories of state capitalism evolved in the first half of the 20th century in response to the European experience of war and fascism; dissident portrayals of the Soviet Union as state-capitalist; post-Second World War theories of state-monopoly capitalism in the Western Bloc; examinations of state capitalism as a development strategy in ‘Third World’ nations in the 1970s and 1980s; and finally, today’s scholarship on new patterns of state capitalism in emerging economies. Having contextualized each of these strands of writing, the article goes on to interrogate definitional and conceptual boundaries of state capitalism. It then maps out essential institutional features of state-capitalist configurations as construed in the literature. In sharp contrast to 20th-century theories of state capitalism, present-day scholarship on the topic tends to retreat from the integrated critique of political economy, shifting its problematics of state-market relations to meso- and micro-levels of analysis.
Hannah Arendt, evil, and political resistance
Authors: Rae Gavin
Published: August 2019

While Hannah Arendt claimed to have abandoned her early conception of radical evil for a banal one, recent scholarship has questioned that conclusion. This article contributes to the debate by arguing that her conceptual alteration is best understood by engaging with the structure of norms subtending each conception. From this, I develop a compatibilist understanding that accounts for Arendt’s movement from a radical to a banal conception of evil, by claiming that it was because she came to reject the foundationalism of the former for the non-foundationalism of the latter, where norms are located from an ineffable ‘source’ diffusely spread throughout the society. While it might be thought that this means that such norms are all-encompassing to the extent that they determine individual action, I appeal to her notions of plurality, action, and natality, to argue that she defends the weaker claim that moral norms merely condition action. This demonstrates how Arendt’s conceptions of evil complement one another, highlights her understanding of the action–norms relation, and identifies that there is built into Arendt’s conception(s) of evil a resource for resisting totalitarian domination.
A novel relative navigation algorithm for formation flight
Authors: Yunfeng Zhu , Yongrong Sun , Wei Zhao , Ling Wu
Published: August 2019

For higher accuracy and better performance, a novel relative navigation framework named full parallel distributed architecture is presented, using inertial navigation system, global positioning system, and data link. Aiming at multiple aircraft, it is designed to enable each plane to serve as a fusion center. Also this structure enhances the collaboration between aircraft by sharing the relative navigation information. It breaks the limitation of the single fusion center method and can adapt to the reconfiguration of formation. A two-stage filtering estimation algorithm based on Kalman filter is developed to determine relative position, attitude, and velocity between the formation aircraft. Each vehicle contains not only a local filter but also a relative state filter, which helps to improve the accuracy of the relative state error model. The relative navigation system is designed as a closed loop system with parallel processing and real-time performance. Simulation results compared with the traditional centralized filtering method indicate that the approach provides better estimates and restrains the error divergency effectively.
‘Am I mad?’: the Windham case and Victorian resistance to psychiatry
Authors: Degerman Dan
Published: August 2019

This article revisits the notorious trial of William Windham, a wealthy young man accused of lunacy. The trial in 1861–2 saw the country’s foremost experts on psychological medicine very publicly debate the concepts, symptoms and diagnosis of insanity. I begin by surveying the trial and the testimonies of medical experts. Their disparate assessments of Windham evoked heated reactions in the press and Parliament; these reactions are the focus of the second section. I then proceed to examine criticism of psychiatry in the newspapers more generally in the 1860s, outlining the political resistance to psychiatry and the responses of some leading psychiatrists. In conclusion, I consider what this says about the politics of medicalization at the time.
Synthesis and effect of metal–organic frame works on CO2 adsorption capacity at various pressures: A contemplating review
Authors: Rehman Ayesha , Farrukh Sarah , Hussain Arshad , Pervaiz Erum
Published: August 2019

The most important environmental challenge that the world is facing today is the control of the quantity of CO2 in the atmosphere, because it causes global warming. Increase in the global temperature results in greenhouse gas emission, interruption of the volcanic activity, and climatic changes. The alarming rise of the CO2 level impels to take some serious action to control these climatic changes. Various techniques are being utilized to capture CO2. However, chemical absorption and adsorption are supposed to be the most suitable techniques for post-combustion CO2 capture, but the main focus is on adsorption. The aim of this study is to provide a brief overview on the CO2 adsorption by a novel class of adsorbents called the metal–organic framework. The metal–organic framework is a porous material having high surface area with high CO2 adsorption capacity. The metal–organic frameworks possess dynamic structure and have large capacity to adsorb CO2 at either low pressure or high pressure due to its cavity size and surface area. Adsorption of CO2 in the metal–organic framework at various pressures depends upon pore volume and heat of adsorption correspondingly. In this review, different synthesis methods of the metal–organic framework such as slow evaporation, solvo thermal, mechanochemical, electrochemical, sonochemical, and microwave-assisted synthesis are briefly described as the structure of the metal–organic frameworks are mostly dependent upon synthesis techniques. In addition to this, different strategies are discussed to increase the CO2 adsorption capacity in the metal organic-framework.

[Formula: see text]
Evolution of the Norwegian plateau icefield Hardangerjøkulen since the ‘Little Ice Age’
Authors: Weber Paul , Boston Clare M , Lovell Harold , Andreassen Liss M
Published: August 2019

The maximum ‘Little Ice Age’ (LIA) glacier extent provides a significant baseline to assess long-term glacier change and to place currently observed rates of glacier recession in a broader temporal context. To that end, we examine the evolution of the plateau icefield Hardangerjøkulen since the LIA. First, we reconstruct Hardangerjøkulen’s maximum LIA extent (~AD 1750) and subsequent recession based on the glacial landform record and aided by historical map interpretation. Ice-marginal moraines, glacial drift limits, trimlines, and identifiable erosion and weathering boundaries provide evidence of a LIA icefield with an area of 110 km2. Existing LIA model simulations of Hardangerjøkulen are not yet fully able to reproduce our reconstructed extent. Second, we compile a set of remotely sensed icefield outlines from successive time points in the 20th and 21st century to calculate icefield area and length change since the LIA. This reveals a substantial reduction in icefield size, with a total area loss of 41 km2 (37%; 2% 10 a–1) by 2010 and a cumulative frontal retreat averaging 1.3 km (29%; 5 m a–1) by 2013. Icefield recession has been greatest since the end of the 20th century, when rates of areal shrinkage increased to 6.5–10% 10 a–1 in 1995–2010, and the rate of average terminus retreat accelerated to 17 m a–1 in 2003–2010. Third, we present a relative dating approach, based on the known age of the different icefield outlines, that allows bracketing ages to be assigned to all ice-marginal landforms between any two outlines. This approach shows that episodes of moraine formation vary temporally between individual outlet glaciers of Hardangerjøkulen, suggesting that the moraine record of a single outlet glacier alone may not be sufficient to derive an icefield-wide picture of past ice advances, and thereby climate fluctuations.
A growing degree day inference model based on mountain birch leaf cuticle analysis over a latitudinal gradient in Fennoscandia
Authors: Ercan Fabian EZ , De Boer Hugo Jan , Wagner-Cremer Friederike
Published: August 2019

Cuticle analysis performed on fossil Betula nana (L.) leaves provides a strong proxy to reconstruct past growing season thermal properties expressed as growing degree days (GDD5). This proxy is so far available for the dwarf birch only and, therewith, restricted to regions or past periods of subarctic climatic conditions. In this study, we analysed modern leaf samples of mountain birch ( Betula pubescens spp. czerepanovii (N. I. Orlova) Hämet-Ahti), which has a wider temperature range than the dwarf birch B. nana. The strong latitudinal climate gradient over Fennoscandia provides a unique opportunity to track growing season temperature imprints in the epidermis cell morphology of the modern mountain birch. We quantified the GDD5-dependent epidermal cell expansion, expressed as the undulation index (UI), over a 10° latitudinal transect translating to a range from ~1500°C to ~600°C GDD5 in 2016. Our results indicate that even in mountain birch the UI is positively correlated to GDD5 and, moreover, is largely independent of regional habitat conditions such as daylight length and precipitation. These results imply that in addition to the earlier studied (sub-)arctic dwarf birch, the closely related mountain birch can also be utilized in GDD5 reconstructions. The abundant presence of fossil mountain birch leaves in sediments from warmer than (sub)arctic palaeoclimates enables the reconstruction of growing season climate dynamics over past phases of climate change, overcoming earlier restrictions of the proxy related to spatial and temporal species occurrence as well as local light regimes.
Body image mediates the impact of pain on depressive symptoms in patients with systemic lupus erythematosus
Authors: Gholizadeh S , Azizoddin D R , Mills S D , Zamora G , Potemra H M K , Hirz A E , Wallace D J , Weisman M H , Nicassio P M
Published: August 2019

Objective

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease with treatment manifestations that can cause changes in appearance, including skin rashes, alopecia, vitiligo, and scars. SLE has been shown to adversely impact body image outcomes, and previous research has identified that greater disease activity is associated with worse body image outcomes which, in turn, are associated with greater depressive symptoms. For patients with SLE who also experience significant pain, poor body image outcomes may further compromise wellbeing and lead to greater depressive symptoms. The role of pain in body image has not been explored in SLE. Thus, the present study examined whether body image (specifically, body image-related quality of life) serves as a mediator of the relationship between pain and depressive symptoms among patients with SLE.

Methods

Multiple mediation analysis was used to examine the hypothesis that body image-related quality of life mediates the relationship between pain and depressive symptoms in a sample of patients with SLE ( N = 135) from an urban region in Los Angeles, California.

Results

The sample was predominately female (92.6%) with a mean disease duration of approximately 17 years. Approximately one-quarter of the sample had elevated depressive symptoms. Body image-related quality of life was a significant mediator in the relationship between pain and depressive symptoms. The model accounted for 51% of the total variance in depressive symptoms ( R2 = 0.51).

Conclusion

This cross-sectional study suggested that body image-related quality of life may mediate the effects of pain on depressive symptoms among patients with SLE.
How Does Transparency Complement Customer Satisfaction and Loyalty in the Restaurant Business?
Authors: Agrawal Shiv Ratan , Mittal Divya
Published: August 2019

The study is an attempt to identify the preferred transparency components from customers’ viewpoint which complements customer satisfaction and loyalty through assurance and reliability in the Indian restaurant business. The study focused on the traditional restaurant settings in Madhya Pradesh (MP), India. A total of 477 usable responses were gathered from customers who dine out frequently in the traditional restaurants. The study disclosed the relative importance of transparency dimensions to improve service-quality dimensions (assurance and reliability) that in turn complement customer satisfaction and loyalty towards the restaurant business.