bluuebunny/crossref_metadata_2025 huggingface dataset:
Numerical Modeling of Roadway Embankment Construction Over Existing Sewers
Authors: Cao Laifa , Peaker Scott
Published: October 2018

This article presents a case study of the influence of a roadway embankment on existing sewers with a diameter or width in the range of 3.3 to 4.3 m using numerical modeling. The proposed embankment would be constructed directly above the existing sewers, which would induce an additional load on the sewers. Traditional analysis methods cannot account for the soil–structure interaction and the benefit of the lateral supporting characteristics of the soils. In order to evaluate the loading of the proposed embankment on the existing sewers, a soil–structure interaction analysis using a two-dimensional finite element analysis was performed for various loading cases. The sensitivity of soil parameters was also studied in the analysis. From the analysis, the loads on the sewers, including axial force, bending moment and shear force, were obtained, and then the structural capacity of the existing sewers was checked. Lightweight sand fill or expanded polystyrene (EPS) geofoam was considered to reduce the additional vertical and horizontal loads on the sewers. The EPS geofoam or a structural protection system consisting of a concrete slab supported by concrete piles was proposed to eliminate any incremental vertical and horizontal loads on the sewers. Findings from the analysis concluded that the lightweight sand fill was the most economical material for reducing the additional loads on the sewers, EPS geofoam was the most suitable material to eliminate incremental loading on the sewers for a lower embankment, and the structural protection system was necessary to eliminate the incremental loads on the sewers for a higher embankment.
Study on the Properties of SCLAC Using Infrared Thermography and Ultrasonic Pulse Velocity
Authors: Chen Tung-Tsan , Hung Ying-Chun
Published: October 2018

A densified mixture design algorithm (DMDA) was employed to produce self-consolidating lightweight aggregate concrete (SCLAC). Lightweight aggregates with different particle densities were evaluated, and the batched water density and water-to-binder (w/b) ratio were varied. The results indicated that the properties of SCLAC mixed according to the DMDA were better than those according to the American Concrete Institute (ACI). Specifically, the slump and slump flow were greater than 250 mm and 500 mm, respectively. For instance, the strength of the material developed quicker; after 7 days of aging, the compressive strength of the specimen was 72 % of the strength obtained after 28 days. Under identical conditions, the compressive strength of SCLAC showed the best development when the w/b ratio was equal to 0.32 (45 MPa after 91 days). When the lightweight aggregate concrete was mixed according to the ACI mixture’s algorithm, the electrical resistivity of the SCLAC reached 53 KΩ-cm and improved to 40 KΩ-cm. The durability of material synthesized according to the DMDA was better than that of the traditional ACI mixture design. The degree of aggregate floating affected the location of the particles and the uniformity of concrete by approximately 20–40 %. Moreover, the results revealed that a low w/b ratio or mixing water density enhanced the development of the pulse ultrasonic velocity. The ability of aggregates with different specific gravities to transmit heat was determined by applying an infrared thermal method, and the results suggested that specimens with different particle densities (800 and 1,300 kg/m3) presented significant differences in temperature variations. Lastly, scanning electron microscopy showed that hydration continued as the age of the material increased, which increased the compressive strength and compactness. In conclusion, a concrete mix designed with DMDA has higher workability and reaches design strength faster.
EFFECTS OF FAT TYPE ON THE TEXTURAL PROPERTIES OF CORN PUREE
Authors: ERİNÇ Hakan
Published: October 2018

In this study, corn flour, milk powder, sugar, emulsifier, and fat (milk fat, palm stearin, sunflower oil and mixture of palm stearin and sunflower oil) were used to produce corn puree. After producing the corn puree, the textural properties of the samples were determined to prepare a formula for a viscoelastic corn puree as a new nutritious product for the food industry. The viscoelastic properties of corn puree samples prepared by various ratios of different fat sources and mix (milk fat, palm stearin, sunflower oil, and a mixture of palm stearin and sunflower oil) were evaluated in the temperature range of 25 to 50°C using a texture analyzer. As the amount of fat increased (40%), the corn puree produced became softer except the sample containing palm stearin, which was found to be harder. As the temperature was reduced, the firmness and work of shear values of purees produced using 10-40% of fat increased.
Mining the Genome: Using Bioinformatics Tools in the Classroom to Support Student Discovery of Genes
Authors: Martins Ana , Fonseca Maria João , Tavares Fernando
Published: October 2018

Adapting research-driven routines to the classroom context can promote innovative and motivational learning environments. Using a case-study approach, we propose a set of bioinformatics-based activities supported by a tutorial video aiming to identify genes and disclosing their genomic context in different species. The rationale is to strengthen teachers’ competencies to introduce bioinformatics resources and tools (e.g., NCBI, ORFinder, BLAST, and MaGe) in their teaching practices. By doing so, teachers will ultimately enhance students’ understanding of how genomic data mining and comparative genomics are instrumental for biological research.
Hacia una didáctica del sentido. Didácticas emergentes de las prácticas pedagógicas de filosofía en tres escuelas católicas
Authors: Nieto Bravo Johan Andrés
Published: October 2018

Ante la poca claridad del papel que ejerce la filosofía como aprendizaje escolar, la presente investigación buscó identificar las didácticas que subyacen de las prácticas pedagógicas en filosofía, a fin de analizar la problemática didáctica del enseñar filosofía o enseñar a filosofar. El enfoque cualitativo de ejercicio investigativo, ha propiciado una aproximación al contexto de tres instituciones educativas católicas y a las comprensiones de estudiantes y docentes que comparten el Espacio Académico de Filosofía. La perspectiva epistemológica hermenéutica, concilia las relaciones de distancia entre los protagonistas que se encuentran en el aula filosófica, a fin de proponer una didáctica del sentido, en donde los significados de la filosofía, se encuentre con los significantes, es decir con los filósofos estudiantes, a fin de construir un conocimiento con sentido. El presente texto presenta el desarrollo de la primera categoría de la investigación, a la cual se le denomina didáctica de la filosofía.
Formación inicial de profesores de ciencias desde los enfoques CTSA y las concepciones Andinas de Vivir bien y Buen vivir
Authors: Ramírez Martínez Jorge Enrique , Beltran Penagos María Alejandra
Published: October 2018

Este artículo presenta una investigación en el ámbito de la formación de profesores de ciencias llevada a cabo en un escenario no convencional de enseñanza aprendizaje, tipo curso electiva, en la Facultad de Ciencia y Tecnología de la Universidad Pedagógica Nacional denominado “Las relaciones ciencia, tecnología, sociedad y ambiente (CTSA) en la formación de profesores de ciencias”. En el desarrollo de esta propuesta de formación e integración curricular, se realizaron actividades de innovación pedagógica y de apropiación social de saber y conocimiento alrededor de temáticas emergentes en la enseñanza como lo son las cuestiones sociocientíficas, las relaciones CTSA y los paradigmas andinos del Buen vivir y Vivir bien, en clave de la formación inicial de licenciados en ciencias de la naturaleza como la Física, la Química y la Biología, y de interdisciplinas como la Electrónica y el Diseño Tecnológico.
Incidencia de los entornos virtuales de aprendizaje en la calidad de la educación superior, desde el contexto colombiano
Authors: González Guerrero Karolina , Berdugo Silva Norma Constanza , Mortigo Rubio Adriana
Published: October 2018

Los procesos de globalización y estandarización en el contexto de educación superior, han traído un referente de implementación y uso de las Tecnologías de la Información y la Comunicación (TIC), como medio para la formación en la educación superior, en la actual sociedad de la información. No obstante, este hecho demanda un análisis crítico acerca de la calidad que se ofrece en este contexto virtual y, en especial, la modalidad concerniente al aprendizaje mixto. Para ello, el estudio muestra una metodología fundamentada, consecuente con la revisión documental y el análisis comparativo de literatura, capaz de establecer un marco de análisis de las implicaciones del b-learning en el contexto de la educación superior. De este modo, la discusión se basa en las relaciones de uso pedagógico de las herramientas y entornos virtuales, en pro de apoyar la formación presencial y, a la par, sustentar un desarrollo educativo de calidad en instituciones de educación superior. A manera de conclusión, se plantea una necesidad de fortalecer los procesos pedagógicos que soportan los recursos utilizados en el b-learning, en tanto se propicie una calidad educativa en términos de eficiencia, pertinencia y la adquisición de competencias para el mundo de la vida.
Perfil profesional del dirigente deportivo regional: Valle del Cauca y Risaralda
Authors: Rodríguez Martha Sandino
Published: October 2018

La dirigencia deportiva en Colombia presenta dos grandes problemas: las personas que son elegidas para los cargos públicos en los entes deportivos territoriales, cuentan con influencia y/o padrinazgo en el campo político; y en el sector privado (asociado), éstos dirigentes regularmente son ex deportistas o familiares de un deportista, sin contar con suficiente conocimiento sobre las funciones y habilidades en el sector. El segundo problema se refiere a la formación. Los actuales dirigentes deportivos no tienen una formación académica que les otorgue las competencias necesarias para desarrollar una adecuada gestión (o gestión de calidad), ni están formados académicamente en administración y gestión deportiva, conocimiento del sector y manejo de un segundo idioma. Normalmente sólo cumplen las 40 horas requeridas para ocupar cargos de dirección deportiva, según la Resolución 00547 del 2010 de Coldeportes. Si se apunta al logro de resultados trascendentes y al desarrollo del sector, un dirigente deportivo debe ser un gerente preparado para asumir con efectividad la gestión y administración de los productos y servicios deportivos. El presente estudio sobre el perfil profesional del Dirigente Deportivo Regional Valle del Cauca y Risaralda - va de la mano con la política pública del sector Plan Decenal del Deporte, la recreación, la actividad física y la educación física en Colombia para el desarrollo humano, la convivencia y la paz 2009-2019, cuyo primer lineamiento está direccionado al fortalecimiento de las organizaciones del sector y para ello se requiere de dirigentes competentes. Se trata de un estudio descriptivo, desarrollado por medio de encuesta aplicada a la población total de presidentes de las Ligas Deportivas de los dos departamentos, con el fin fundamental consiste en conocer su nivel de formación sobre administración y gestión deportiva y su experiencia en el sector en cargos de dirección.
Manual de Política Normativa Para una Institución de Educación a Distancia
Authors: Vela González Pedro Antonio , Ahumada De la Rosa Vicky Del Rosario , Guerrero Rodríguez José Humberto
Published: October 2018

En las instituciones educativas que ofertan programas bajo cualquier modalidad de educación, se hace necesario el análisis, diseño, desarrollo, implementación y evaluación de un manual de política normativa que permita el aseguramiento de la calidad educativa impartida. En esta revisión literaria se presentan criterios básicos a considerar por parte de una Institución de Educación a Distancia (IED) en lo que respecta a las generalidades, condiciones y componentes de las áreas filosófica, jurídica, fiscal, geográfica y de dirección académica, administrativa y financiera, tecnológica, profesoral y estudiantil, elementos que constituyen el manual de política normativa. Se presentan como anexo, algunos referentes en relación con la política normativa para Colombia que, con su obligatoriedad en la aplicación, permite garantizar por parte de las instituciones educativas la prestación de un servicio de alta calidad.
Estilos de aprendizaje y motivación, la clase de inglés en séptimo grado
Authors: Norato Peña Adriana Melina
Published: October 2018

En clase de inglés avanzado del grado séptimo, se observaron dificultades en el cumplimiento y desempeño de la mayoría de los estudiantes. Por ello, se inició un ejercicio de observación para el diagnóstico de los estilos de aprendizaje y la motivación de los estudiantes en clase de inglés. A partir de los estilos de aprendizaje diagnosticados, se diseñó un plan de acción, en el marco de la investigación acción, nuevas pautas de trabajo hacia la motivación para el trabajo, mejora del desempeño y el cumplimiento. Como resultado de la investigación se logró mejorar la motivación y el desempeño de los estudiantes en clase a través de autoconocimiento de los estilos de aprendizaje; y por otra parte, mejorar el desarrollo profesional de la profesora en el diseño de clase y en la capacidad de observación, reflexión y búsqueda de soluciones a las situaciones de clase
Development of Learning Video using Guided Inquiry Methods on Circular Motion Subject to Improve Student Learning Outcomes
Authors: Astra I Made , Raihanati Raihanati , Hafizah Syarifah
Published: October 2018

AbstractThis study aims to develop a learning video on circular motion subject as a physics learning media for high school students. The developed video is prepared based on the guided inquiry learning stage and completed with the Student Worksheet. This research used Research and Development (R&D) method, with ADDIE model. The developed video has been through feasibility test with the achievement percentage of 91.8% from material expert, 96.8% from media expert, and 85.9% from learning expert with excellent interpretation. The product trial results show the percentage of achievement of 81.7% from educator and 89.4% from learner. There is an increase of result was 54.4 to 79.8 with a normalized gain test of 0.56 Based on the result of feasibility test and experiment, it can be concluded that instructional video using guided inquiry method in circular motion subject is worth to be used as physics learning media in senior high school and improved students’ learning outcomes in medium category.AbstrakPenelitian ini bertujuan untuk mengembangkan video pembelajaran pada materi gerak melingkar sebagai media pembelajaran fisika untuk siswa SMA. Video yang dikembangkan disusun berdasarkan tahapan pembelajaran inkuiri terbimbing dan dilengkapi dengan Lembar Kerja Siswa (LKS). Penelitian ini menggunakan metode Research and Development (R&D), model ADDIE. Video yang dikembangkan telah melalui tahap uji kelayakan dengan persentase pencapaian 91.8% menurut ahli materi, 96.8% menurut ahli media, dan 85.9% menurut ahli pembelajaran dengan interpretasi sangat baik. Hasil uji coba produk menunjukkan persentase pencapaian 81.7% menurut pendidik dan 89.4% menurut peserta didik. Melalui uji coba kepada peserta didik, didapatkan kenaikan dari hasil pretest sebesar 54.4 menjadi 79.8 saat postest. Berdasarkan hasil uji kelayakan dan uji coba dapat disimpulkan bahwa video pembelajaran menggunakan metode inkuiri terbimbing pada materi gerak melingkar hasil pengembangan telah layak digunakan sebagai media pembelajaran fisika SMA.
Strengthening and Transformation of the Islamic Education System in Malaysia
Authors: Suhid Asmawati
Published: October 2018

AbstractEducation is an important aspect in fulfilling the mission and human development agenda. Hence, Islam places great importance in education as was stated in the first verse revealed to the Prophet Muhammad (PBUH). In Malaysia, education is also a priority in the country’s development including Islamic education.  The Islamic Education System in Malaysia is constantly evolving and changing in order to meet the needs and demands of the society. Parents and societies who are increasingly interested and realised the importance of Islamic education have created various forms and types of Islamic education.  As an example, the emergence of Maahad Tahfiz, Ulul Albab programme, private Islamic Schools, Darul Quran and the J-QAF programme showed a very encouraging improvement.  Attention is also given to the children of young prisoners and married teenagers in order they are not left behind in the mainstream education. Hence, this paper will discuss the development, strengthening and transformation of the Islamic education system in Malaysia besides highlighting some research findings that support this discussion. Abstrak Pendidikan merupakan aspek penting dalam memenuhi misi dan agenda pembangunan manusia. Oleh karena itu, Islam menekankan pentingnya pendidikan seperti Firman dalam ayat pertama yang diwahyukan kepada Nabi Muhammad (SAW). Di Malaysia, pendidikan juga menjadi prioritas dalam pembangunan negara termasuk pendidikan Islam. Sistem Pendidikan Islam di Malaysia terus berkembang dan berubah untuk memenuhi kebutuhan dan tuntutan masyarakat. Orang tua dan masyarakat yang semakin tertarik dan menyadari pentingnya pendidikan Islam telah menciptakan berbagai bentuk dan jenis pendidikan Islam. Sebagai contoh, munculnya Pesantren Tahfiz, Program Ulul Albab, Sekolah Islam swasta, Darul Quran dan program J-QAF menunjukkan peningkatan yang sangat menggembirakan. Perhatian juga diberikan kepada tahanan anak-anak dan remaja yang sudah menikah agar mereka tidak tertinggal dalam meraih pendidikan pada umumnya. Oleh karena itu, dalam artikel ini penulis akan membahas tiga topik utama; pengembangan, penguatan dan transformasi sistem pendidikan Islam di Malaysia. Dalam rangka mendukung diskusi, beberapa temuan penelitian akan disorot.
Motivational Interviewing to Treat Adolescents With Obesity: A Meta-analysis
Authors: Vallabhan Monique K. , Jimenez Elizabeth Y. , Nash Jacob L. , Gonzales-Pacheco Diana , Coakley Kathryn E. , Noe Shelly R. , DeBlieck Conni J. , Summers Linda C. , Feldstein-Ewing Sarah W. , Kong Alberta S.
Published: October 2018

CONTEXT:

Successful treatment approaches are needed for obesity in adolescents. Motivational interviewing (MI), a counseling approach designed to enhance behavior change, shows promise in promoting healthy lifestyle changes.

OBJECTIVE:

Conduct a systematic review of MI for treating overweight and obesity in adolescents and meta-analysis of its effects on anthropometric and cardiometabolic outcomes.

DATA SOURCES:

We searched Medline, Embase, Cumulative Index to Nursing and Allied Health Literature, PsychINFO, Web of Science, Cochrane Library, and Google Scholar from January 1997 to April 2018.

STUDY SELECTION:

Four authors reviewed titles, abstracts, and full-text articles.

DATA EXTRACTION:

Two authors abstracted data and assessed risk of bias and quality of evidence.

RESULTS:

Seventeen studies met inclusion criteria; 11 were included in the meta-analysis. There were nonsignificant effects on reducing BMI (mean difference [MD] −0.27; 95% confidence interval −0.98 to 0.44) and BMI percentile (MD −1.07; confidence interval −3.63 to 1.48) and no discernable effects on BMI z score, waist circumference, glucose, triglycerides, cholesterol, or fasting insulin. Optimal information size necessary for detecting statistically significant MDs was not met for any outcome. Qualitative synthesis suggests MI may improve health-related behaviors, especially when added to complementary interventions.

LIMITATIONS:

Small sample sizes, overall moderate risk of bias, and short follow-up periods.

CONCLUSIONS:

MI alone does not seem effective for treating overweight and obesity in adolescents, but sample size and study dose, delivery, and duration issues complicate interpretation of the results. Larger, longer duration studies may be needed to properly assess MI for weight management in adolescents.
Supporting the Health Care Transition From Adolescence to Adulthood in the Medical Home
Authors: White Patience H. , Cooley W. Carl ,   TRANSITIONS CLINICAL REPORT AUTHORING GROUP, AMERICAN ACADEMY OF PEDIATRICS, AMERICAN ACADEMY OF FAMILY PHYSICIANS, AMERICAN COLLEGE OF PHYSICIANS
Published: October 2018

Risk and vulnerability encompass many dimensions of the transition from adolescence to adulthood. Transition from pediatric, parent-supervised health care to more independent, patient-centered adult health care is no exception. The tenets and algorithm of the original 2011 clinical report, “Supporting the Health Care Transition from Adolescence to Adulthood in the Medical Home,” are unchanged. This updated clinical report provides more practice-based quality improvement guidance on key elements of transition planning, transfer, and integration into adult care for all youth and young adults. It also includes new and updated sections on definition and guiding principles, the status of health care transition preparation among youth, barriers, outcome evidence, recommended health care transition processes and implementation strategies using quality improvement methods, special populations, education and training in pediatric onset conditions, and payment options. The clinical report also includes new recommendations pertaining to infrastructure, education and training, payment, and research.
Prevalencia y factores asociados al sobrepeso y obesidad en escolares peruanos del nivel primario
Authors: Tarqui-Mamani Carolina , Alvarez-Dongo Doris , Espinoza-Oriundo Paula
Published: October 2018

Objetivos Determinar la prevalencia y factores asociados al sobrepeso y obesidad en escolares peruanos.Métodos Estudio transversal durante el 2013-2014. El muestreo probabilístico, estratificado multietápico, se incluyó 1 191 conglomerados con 7 914 viviendas (área urbana: 4 842 y rural: 3 072) en Perú. Se evalúo 2 801 escolares entre 5 a 13 años. Se empleó el Z score del índice de masa corporal para la edad (ZIMC) según OMS. Se consideró sobrepeso (ZIMC>1 y ≤2) y obesidad (ZIMC>2).Resultados El 18,1% tuvieron sobrepeso y 14,1% obesidad. El sobrepeso predominó en varones (18,7%), escolares de 8 a 10 años (19,6%), no pobres (21,2%), área urbana (21,6%), Lima Metropolitana (22,8%) y Costa (22,7%). La obesidad predominó en varones (19,1%), escolares de 8 a 10 años (17,9%), no pobres (18,5%), área urbana (20,2%), Lima Metropolitana (28,0%) y Costa (18,2%). Los factores asociados al sobrepeso fueron la no pobreza (OR=1,9), vivir en área urbana (OR=1,7), Lima Metropolitana (OR=1,9) y Costa (OR=1,6); mientras que ser hombre (OR=3,1), nivel educativo secundario del jefe del hogar (OR=1, 8), superior (OR=2,5), no pobre (OR=9,2), residir en área urbana (OR=3,4), Lima Metropolitana (OR=4,8) y Costa (OR=2,9) se asociaron con la obesidad.Conclusiones La prevalencia de obesidad o sobrepeso de los escolares es alta. La condición de no pobreza, vivir en área urbana, Lima Metropolitana y Costa se asocian al sobrepeso. Ser hombre, no pobre, el mayor nivel educativo del jefe del hogar, vivir en el área urbana, Lima Metropolitana y Costa se asocia a la obesidad.
Krónikus, nem bakteriális, multicentrikus osteomyelitis a mandibulában
Authors: Danka Eszter , Pintér Gábor Tamás , Keresztúri Márton , Szabó György
Published: October 2018

Abstract:

Chronic nonbacterial osteomyelitis is a sterile inflammatory osteitis that most commonly develops in the long bones, but it can occur in any bone. Mandibular lesions are found in 1.5–3% of disease foci in patients and it is poorly characterized in the maxillofacial surgery literature due to the use of inconsistent terminology. The purpose of this study was to present the clinical experience of chronic nonbacterial multicentric osteomyelitis and a collection of research and information of the disease. This is a retrospective study of 2 cases with mandibular lesions radiographically consistent with osteomyelitis without infection. Medical records were reviewed for history, clinical features, imaging and pathology. The study included 2 patients (2 females, age of 17 and 43 years). Both reported mandibular pain and swelling, radiographic finding of multifocal intraosseal inflammatory lesions. Computed tomography scans typically showed expansion of the affected mandible with sclerosis of the medullary space, small foci of poorly defined lytic destruction with lamellated periosteal reaction. Both patients showed a long ineffective antibiotic therapy and recurrent flare-ups of inflammation. After the proper course of treatment (nonsteroid and steroid therapy), a long painless period was reached. Chronic multicentric nonbacterial osteomyelitis has been reported to be uncommon in the mandible, but it may be more common with correct diagnosis, typified by recurrent pain and swelling with characteristic pathologic and radiologic features. The current treatment modalities include nonsteroidal anti-inflammatory drugs or steroids. Orv Hetil. 2018; 159(43): 1761–1766.
FATTY ACID PROFILE AND NUTRITION VALUES OF MICROALGA (Thalassiosira pseudonana) COMMONLY USED IN WHITE SHRIMP (Litopenaeus vannamei) CULTURING
Authors: Nguyen Cong Van
Published: October 2018

Microalga Thalassiosira pseudonana is an important feed item in the aquaculture industry nowadays and its biomass is essential for white leg shrimp seeding production. Microalga T. pseudonana were grown under optimal conditions (salinity of 30 - 31 ‰; pH 7.5 - 8.5; temperature 25 - 27 oC; light intensity 5.5 klux with light: dark period 12:12 h; alkalinity 150 - 180 ppm; media of AGP 20 %; initial cell density 0.2 x 106 cells/ml; 24 hour aeration mode) and harvested during log phase after 6 days of cultivation. The obtained results showed that microalga T. pseudonana possess both EPA (eicosapentaenoic acid, C20:5 n-3) and DHA (docosahexaenoic acid, C22:6 n-3) fatty acids. Particularly, its fatty acid composition is mainly C16:0 (38.060 % compared to total fatty acid - TFA), C16:2n - 4 (12.850 % TFA), 16:3n - 3 (8.873 % TFA), C20:5n - 3 (16.423 % TFA) and 22: 6 (n - 3) (1.650 % TFA). Also, the C16:1n - 7 (6.147 %), C16:1n - 9 (4.737 % TFA), C18:1n - 7 (1.370 % TFA), C18:1n - 9 (2.063 % TFA) and C20:1n - 7 (0.677 % TFA) which were obtained those play a crucial role in aquaculture activities. Additionally, the total content of SFAs, MUFFAs and PUFFAs were 42.539, 14.994 and 42.443 % TFA, respectively. The protein, carbohydrate, chlorophyll a, carotenoids, lipid contents was reach 13.20 ± 0.01 %, 9.96 ± 0.12 %, 1.01 ± 0.13 %, 0.15 ± 0.01 %, 20.79 ± 0.24 % of dry cell weight, respectively. Moreover, T. pseudonana biomass contains a large variety of minerals and micronutrients such as Na (27.80 %/kg), K (0.93 %/kg), I (55.10 mg/100g), Fe (222.74 mg/kg), Cu (1.96 mg/kg), Mn (3.11 mg/kg), Mg (2.52 %/kg), Ca (0.97 %/kg), Co (< 0.10 mg/kg) and undetectable B. Importantly, the heavy metals contents such as Cd, Pb, As and Hg was met to the Vietnam standard for aquaculture feed.
EFFICIENT CONJUGATION OF AFLATOXIN B1 WITH BOVINE SERUM ALBUMIN APPLYING FOR DEVELOPMENT OF AFLATOXIN B1 QUICK TEST
Authors: Phong Truong Quoc , Phạm Ngọc Thị , Nguyen Huong Dieu , Nguyen Anh Thi Ngoc
Published: October 2018

Aflatoxins are secondary metabolites mostly produced by Aspergillus flavus and Aspergillus parasiticus and found in agricultural foodstuff such as maize grains, peanuts, animal feeds,... These are toxic and cancerous agents for humans and animals. Among them, aflatoxin B1 is the most consideration due to its highest toxicity and presence in samples. Several methods were developed to detect aflatoxin in food, feed and other foodstuffs such as chromatographic methods (TLC, HPTLC, HPLC), LC-MS/MS, FTIR, RIA, ELISA, SPR, electrochemical, and immunodipstick. Among them only immunodipstick method is compatible for field usage. Therefore, aim of the present study is to determine optimal condition for conjugation of aflatoxin B1 (AFB1) with bovine serum albumin (BSA) to develop a lateral flow immunoassay test strip for detection of aflatoxin B1. Optimal conditions for generating mediate compound of aflatoxin B1 – CMO was investigated: AFB1:CMO ratio of 1:2, reflux temperature of 100oC for 2 hours. Concentration of aflatoxin B1 in reaction was 0.27 µg/µl. Conjugation of AFB1 with CMO was confirmed by thin layer chromatography, HPLC and FT-IR methods. Furthermore, optimal conditions for conjugation of mediate AFB1-CMO derivative with BSA were also investigated. Ratio of AFB1-CMO with BSA was determined as 40:1 and equal to predicted theoretical ratio. Efficient conjugation conditions were 25oC for 2 hours in bicarbonate buffer pH 9.5. Generated conjugate of AFB1-BSA was successfully applied to construct a lateral flow immunoassay test strip for detection of aflatoxin B1
ANTIOXIDANT PROPERTIES OF FOLIC ACID: A DFT STUDY
Authors: Duy Quang Dao
Published: October 2018

Antioxidant activity of folic acid (FA) was investigated via two main antioxidant mechanisms: hydrogen atom transfer (HAT) and single electron transfer (SET) at the DFT/B3LYP/6-311G(d,p) level of theory. The characterizing thermochemical properties such as bond dissociation enthalpies (BDEs), ionization energy (IE) and electron affinity (EA) were calculated in the gas phase. Analyses of HOMOs distribution shows that the postions which easily donate electrons to free radicals are essentially found at C ring, while the positions which easily accept electrons (LUMOs) from radicals are mainly situated at B ring. The lowest BDE values equal to 76.5 and 80.1 kcal/mol are obtained at C19-H and C9–H position, respectively. It is showed that FA represents a potential antioxidant via HAT mechanism. In addition, the IE and EA values calculated in the gas phase are equal to 5.45 eV and 1.87 eV, respectively. This result shows that FA has higher ability to donate electrons into free radicals, while the ability to receive electrons is quite weak. Finally, the HAT reaction between FA and reactive radical like HOO• was also calculated at the same level of theory. This provides more insight into its mechanism on free radicals scavenging.
EFFECTS OF SUBSTITUENTS ON CH BOND DISSOCIATION ENTHALPIES OF ENT-KAURANE DITERPENOIDS: A DFT STUDY
Authors: Dang Hai Ngo Truong , NGO Chinh Thi , PHAM Quan Minh , PHAM Long Quoc , Dao Quang Duy
Published: October 2018

C-H bond dissociation enthalpies (BDEs) of seven ent-kaurane diterpenoids extracted from Croton tonkinensis Gagnep. have been investigated by using density functional theory (DFT) method. The calculations were performed at the M05-2X/6-31+G(d) level of theory. Additionally, insight into the effects of different substituents including –NH2, –OH, –NO2, –SH, –CN, –Cl, –CONH2, –CH-(CH3)2, –NHCOCH3, –OCOCH3 and –C2H5 on BDE have also been provided. The results showed that the BDE value of ent-16(S)-18-acetoxy-7b-hydroxykaur-15-one compound is lowest, being 83.5 kcal/mol. Among substituents binding at C16 position of this molecule, –NH2 has the most remarkable influence on the BDE (C-H) value. Indeed, the BDE of C16-H significantly decreases from 83.5 to 68.4 kcal/mol when replacing –CH3 group by –NH2 one at the C16 position. The obtained results may provide more information for organic synthesis of ent-kaurane based – novel antioxidant compounds.
APPLICATION OF IMAGE-BASED HIGH CONTENT ANALYSIS FOR THE SCREENING OF BIOACTIVE NATURAL PRODUCTS
Authors: Nghi Do Huu , Huong Le Mai
Published: October 2018

Each bioactive compound induces phenotypic changes in target cells that can be made visible by labelling selected molecules of the cells with fluorescent dyes and/or directly observed under the high-throughput microscope. A comparison of the cellular phenotype induced by a compound of interest with known cellular targets allows predicting its mode of action. Over the past 15 years, high-throughput microscopy has been one of the fastest growing fields in cell biology. When combined with automated multiparametric image and data analysis, it is referred to as high-content screening (HCS). Whilst HCS has been successfully applied to the bioactivity characterization of natural products, recent studies used automated microscopy and software to increase speed and to reduce subjective interpretation. In 2017, Institute of Natural Products Chemistry (INPC-VAST) has been equipped with a HCS platform (Olympus Scan^R) that designed for fully automated image acquisition and analysis of biological samples to visually inspect the cellular morphology induced by hit compounds as well as to discriminate from false positives. Accordingly, this short review covers the concepts of HCS and its application in screening of biologically active natural products whose molecular targets could be identified through such approaches.
RESEARCH ON PHYTOCHEMICAL AND ALFA-GLUCOSIDASE INHIBITORY ACTIVITY OF ETHYL ACETATE FRACTION OF RUELLIA TUBEROSA
Authors: Le Dung Tien
Published: October 2018

ABSTRACT-HCTN75Rullia tuberosa L. is a folk remedy in the treatment of diabetes mellitus, anti inflammation and diuretic agent. However, its hypoglycemic activity has not been investigated so far. In the present study, the antidiabetic activity of the n-hexane, ethyl acetate and methanol fraction of crude ethanolic extract of this plant were investigated. Our preliminary results showed that the crude ethanol extract as well as ethyl acetate and methanol fractions of Ruellia tuberosa showed α-glucosidase inhibitory activity with IC50 of 15.84, 4.73 and 8.27 µg/ml, respectively. From the ethyl acetate extract of whole plant of Rullia tuberosa, four compounds, including rutin (1), syringaresinol (2), catechin (3) and pulmatin (4) were isolated and identified by column chromatography. Their structures were elucidated by spectroscopic method including MS, 1D and 2D- NMR and comparison with the literature values.
Üniversite Öğrencilerinin Naylon Poşet Kullanımına İlişkin Tutum ve Davranışlarının Yapısal Eşitlik Modellemesiyle Araştırılması
Authors: GÜRBÜZ Hüseyin , YILMAZ Veysel
Published: October 2018

Naylon poşetin hammaddesi yenilenebilir olmayan ve doğada çok uzun süreler bozulmayan kaynaklardan elde edilmektedir. Toplumda, yanlış bilgilenme sonucunda naylon poşetlere geri dönüşüm işlemi uygulandığını düşünülmesi yanlış tercih ve kullanımlar yol açabilmektedir. Günümüzde geri dönüşüm işlemi sonucu üretilen naylon poşetler hepimizin bildiği siyah naylon poşetlerdir. Siyah naylon poşetler birçok ülkede yasaklanmasına rağmen ülkemizde sadece birkaç ilde yasaktır. Dünyada naylon poşet kullanımına ilişkin birçok kampanya başlatılmıştır. Bu kampanyalar yardımıyla tüketici bilinçlendirilmeye çalışılmaktadır. Ülkemizde ise bu tür kampanyalar az olup ancak il bazında yapılmaktadır. Bu tespitler ışığında çalışmanın amacı, Eskişehir Osmangazi Üniversitesi İstatistik Bölümü öğrencilerinin naylon poşet yerine bez torba tercih etmelerine ilişkin tutum ve davranışlarının araştırılması olarak belirlenmiştir.
ASSESSMENT OF LOGISTICS SUSTAINABILITY IN FAMILY FARMS BASED ON THE LSR CONCEPT
Authors: Wajszczuk Karol
Published: October 2018

This paper is an assessment of sustainable logistics in family farms based on the LSR concept. The introduction clearly illustrates the significant contribution of logistics to the sustainable development of farms. For the purposes of this study, five Polish family farms were selected, located in the Wielkopolskie voivodeship, managing arable land with an area ranging from 32 ha to 131 ha, focused on mixed (plant + animal) production with various field arrangement patterns. This study uses a measurement methodology for logistics sustainability, addressing five key areas of LSR, i.e.: purchasing social responsibility (PSR), sustainable transportation (ST), sustainable packaging (SP), sustainable warehousing (SW) and reverse logistics (RL). According to the results, there is a weak (albeit growing) positive correlation between the logistics sustainability level and the area of land, whether it comes to specific main LSR processes or to social, environmental and economic aspects.
IMPACT OF CHANGES IN AGRICULTURAL COMMODITY PRICES ON CHANGES IN RETAIL PRICES OF AGRI-FOOD PRODUCTS IN POLAND IN 2007–2016
Authors: Mierzejewski Mateusz
Published: October 2018

This paper presents the impact of changes in prices of agricultural products on changes in retail prices of agrifood products. The basis for the study was data on changes in prices of milk, wheat, pork and poultry and derived products in Poland in 2007–2016. A relationship was discovered between the variables, on one side, and lags between the examined time series, on the other. The cross-spectral analysis was used to study the periodicity of changes and lags between time series.
ESTIMATION OF EFFICIENCY OF IMPERVIOUS SCREEN AT THE DON MAIN CHANNEL
Authors: ISHCHENKO Aleksandr V. , BAEV Oleg A.
Published: October 2018

The article gives an evaluation of the effi ciency of the Don main canal impervious screen, fi eld observation on the canal section before and after reconstruction are carried out. To estimate the eff ectiveness of the impervious measure, comparative calculations are carried out for the canal section before the reconstruction (in the earthen channel) and after it (with facing from geocomposite bentonite mats), conclusions are drawn and recommendations for channel operation are made.
DEVELOPMENT OF URBAN TYPOLOGY OF ITALIAN MARKETS IN THE CONTEXT OF LOCAL FEATURES
Authors: GEORGIEVSKAYA Alina O.
Published: October 2018

The purpose of the paper is to identify the typology of Italian markets in the urban context. On the basis of interdisciplinary research and the author’s observations the paper considers the key factors infl uencing the relevance, functioning and location of Italian markets in the urban structure. The analysis takes into account cultural, historical and economic features of the development of the typology, including the integration into the urban lifestyle through the working time of Italian markets. The results of the study allow us to understand the identity of Italian markets and to draw parallels with the Russian ones.
ARCHITECTURAL AND HISTORICAL ENVIRONMENT UNDER THE CONDITIONS OF A DYNAMICALLY DEVELOPING MEGAPOLIS
Authors: VAVILONSKAYA Tatiana V.
Published: October 2018

The article reveals the main milestones of the development of the architectural and historical environment of the city of Samara as a dynamically developing metropolis. The studies conducted in the post-Soviet period aimed at preserving the environment and resulting from security activities and practical works of the same period aimed at updating the architectural and historical environment and resulting from urban development are critically interpreted. The article reveals the causes of the violation of the integrity of the architectural and historical environment of a large Volga city. One of the main reasons is the contradiction between the various objectives of security and urban development. Part of the analyzed researches and studies were carried out with the participation and (or) under the guidance of the author of this article.
INTEGRATION OF HIGH-RISE BUILDINGS IN HISTORICAL ENVIRONMENT
Authors: GENERALOVA Elena M.
Published: October 2018

The article views the urbanization processes which are linked with continuous transformation of city for increasing of its eff ectiveness in accordance with requirements to the environment. The actual questions of the method of interaction of diff erent historical layers in urban environment are broached. The methods and means of integration of old and new are discovered on the example of design of modern high-rise complexes with their inclusion into historical objects structure. For scientifi c justifi cation of criteria of integration of existing buildings and new development in terms of vertical urban growth the concept of «hybridization method» is proposed. This method assumes that the relationship of the old and the new is based on complementary interaction principles. The examples of eff ective integration of high-rise buildings and historic houses are given with a comprehensive analysis of town planning, space planning, social and economic, demographic, environmental, technological and the other factors.
STUDIES OF DEFLECTIONS OF STATICALLY DETERMINED REINFORCED CONCRETE BEAMS BASED ON A NONLINEAR DEFORMATION MODEL
Authors: PANFILOV Denis A. , CHEGLINTSEV Vladimir Yu. , ROMANCHIKOV Vyacheslav V. , ZHILTSOV Yury V.
Published: October 2018

In this paper theoretical studies of statically determinated bending reinforced concrete beams of rectangular cross-section on deformation indexes under the eff ect of a short-time uniformly distributed load are viewed. These theoretical studies are based on the main points of the nonlinear deformation model that takes into account the nonlinear work of concrete and fi tments taking into account discrete cracking. The results of calculating the deformation of beams by the method of SP 63.13330.2012 and by authors’ method are proposed as well as the results of a numerical experiment with the identifi cation of the stress-strain state of statically determinated beams in the form of a fi nite element model in the program complex «Lira CAD-2017R3» using a linear and non-linear sett ing of characteristics of concrete and reinforcement. Based on the results of theoretical studies, the calculation results by the methodology of the current standard with a numerical experiment, as well as with the authors’ calculation methodology are compared. All calculations and loading schemes in this technique are given taking into account the possibility of further experimental studies.
MICROGRID BASED ON A GROUP OF AUTONOMOUS OPERATING SYNCHRONOUS GENERATORS
Authors: ARTYUKHOV Ivan I. , STEPANOV Sergey F. , BOCHKAREV Dmitriy A. , TULEPOVA Gulsim N. , ZEMTSOV Artem I.
Published: October 2018

The current level of power electronics development allows creating and implementing new technologies for generation, transmission and distribution of electricity. Electric machines with variable shaft speed can be used as an energy source now. The functions of providing the parameters of the generated electric power are transferred to the converter devices. The combination of controlled energy sources and electrical receivers in microgrids allows reducing energy losses, increasing the reliability of electricity supply. The article is devoted to the constructions of a microgrid based on several autonomously operating synchronous generators. As an example, microgrid for power supply of compressor station based on own use generators of gas compressor units is considered.
DETERMINATION OF LATERAL PRESSURE OF LIGHT CONCRETE MIX LAID IN THE FORMWORK ACCORDING WITH EXISTING TECHNIQUES AND INSTALLATION PROCESS MODELING FROM THE POSITION OF OPERATIONAL IMPACTS
Authors: RYAZANOVA Galina N. , PROKOPYEVA Anastasia Yu.
Published: October 2018

The analysis of existing Russian and foreign methods for determination of lateral pressure of light concrete mix laid in the formwork, its scope and technological factors is proposed as well as the study of the processes associated with the laying of light concrete mixture in the formwork system from the position of the resulting operational impacts. The results reveal that the pressure on the formwork for these methods depends on speed of concreting of the structure, and the distribution of lateral pressure light concrete mixture according to the height of the formwork is similar to the eff ects of heavy concrete and may be made by analogy with the plots of hydrostatic pressure, it is necessary to bring the properties of light concrete mix that consolidate by vibration to the properties of the heavy liquids with the corresponding density values.
THE ZETA-POTENTIAL AS A UNIVERSAL TECHNOLOGICAL INDICATOR OF WATER QUALITY
Authors: KICHIGIN Viktor I. , CHERNYAGINA Elizaveta D.
Published: October 2018

Were identifi ed based on the changes in ζ-potential from physical and chemical indicators of source and waste waters. It is established that in the process of washing vehicles changed signifi cantly such water quality parameters as its color, turbidity and alkalinity. Change the values of other indicators were within the statistical errors. It is proved that the increase of colour of water (and, probably, its turbidity) the range of values of the zeta-potential (ζ-potential) has narrowed. In the waste water compared to the original, the range of alkalinity values was much wider, but with a smaller range of changes in ζ-potential.
SUSTAINABLE OPERATION OF THE SEWAGE WORKS IN CRITICAL SITUATIONS
Authors: VILSON Elena V. , SERPOKRYLOV Nikolay S. , DOLZHENKO Lidiya A.
Published: October 2018

The causes of critical situations in sewage treatment plants for municipal water disposal are analyzed. A survey of local treatment facilities of the microdistrict in a critical failure situation was carried out and problems were identifi ed, caused by the discharge of either under-treated or completely untreated sewage into the reservoir. To restore the functioning of treatment facilities an optimal technological regime has been developed, taking into account changes in air supply, introduction of biologics, addition of hydrogen peroxide and the use of LEDs in the aerobic part of structures.
INTEGRATED ASSESSMENT OF THE CONDITION OF URBANIZED AREAS
Authors: KONSTANTINOV Igor S. , ZVYAGINTSEVA Anna V.
Published: October 2018

Based on the use of statistical information from various organizations, an assessment of the state of the urbanized territories has been performed on a set of indicative indicators. To this aim, a method of complex estimation based on the representation of states of objects through a combination of values of indicators and joint events of their simultaneous observation, as well as on the establishment of empirical distributions of such events was proposed. The application of the method allowed to propose calculated dependencies for the ranking of objects. Specifi c examples show that based on the proposed method, a comparative assessment of urban areas is possible. The obtained results can be used in the formation of goals and the development of measures to ensure a balanced development of urban infrastructure, as well as in the development of urban development programs and management decisions in the fi eld of environmental safety of urban economy.
DEFINING TYPOLOGICAL STRUCTURE OF MIXED-USE TALL BUILDINGS
Authors: GENERALOVA Elena M.
Published: October 2018

The article deals with an actual problem of fi nding techniques and methods to create a comfortable urban environment. The author emphasizes that in the existing conditions of intensive urban development greater att ention should be given to spatial concentration based on and more compact distribution of population in urban space. It is stressed that including mixed-use facilities into urban realm results in a signifi cant improvement of living environment qualitative characteristics. The author explores the world’s experience of designing tall mixed-use buildings and reveals modern trends in their construction.
FORMING THE IDENTITY OF PUBLIC OBJECTS ON THE EXAMPLE OF SAMARA
Authors: KOSENKOVA Natalya A. , SEROVA Alina A.
Published: October 2018

The purpose of the article is to identify the infl uence of the system of priority identifi ers on the architecture of public objects in Samara in the historical stages, from the time of the foundation of the city (1586) to the present time. On the example of some heritage objects the diff erence between the architectural and historical environment and its uniqueness is shown. The conclusion is made that the preservation of the identity of the place is the most important principle of sustainable development of the architectural and historical environment, since the historical and cultural heritage must be transferred to the future. As a result, the image of the Samara residential development along the whole path of its development was determined, the types, styles, impacts of the external and internal ethnos, as well as the productive forces that are the basis for the development of the city in each historical period.