bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigation of university students' attitudes toward web-based distance education in terms of theoretical and applied courses during the COVID-19 pandemic period
Authors: BARĞI Gülşah , AKKAYA Mehmet Egemen , GÜNEY Yiğit Ege
Published: September 2022

University students had to switch from face-to-face education to web-based distance education (WBDE) owing to new coronavirus disease (COVID-19) pandemic. While theoretical courses can be provided properly with WBDE, it has been thought that applied courses cannot be sustained effectively by the same way. University students’ attitudes toward WBDE regarding theoretical and applied courses taught in physiotherapy and rehabilitation department has not been investigated yet, which was therefore aimed in current study. This cross-sectional study included university students (n=180, 20.14±1.57 years) who still maintain actively WBDE at Izmir Democracy University, Physiotherapy and Rehabilitation Department. “Scale for Evaluating Students’ Attitudes/Opinions/Thoughts Regarding Applied and Theoretical Courses in Distance Education” was generated by the researchers and performed through online platform. Scale comprised 26 items. Each item is scored as from 5 (completely agree) to 1 (strongly disagree). Proper factor analyses were performed and repeated until the items were found to be significant. Factor loads of final 16-item ranged from 0.27 to 0.84. All fit indices (χ2/SD=1.42) were within acceptable limits. One-dimensional structure of scale was confirmed with 16 items. Cronbach Alpha internal consistency coefficient was found to be 0.916, and total correlations of the items varied between 0.422 and 0.772. This scale was found to be highly reliable. Internal consistency between items was high. Maximum score obtained from scale is 80. Total score of students (39.91±10.97) showed that attitudes/opinions/ideas regarding theoretical and applied courses through WBDE were negative. These negative attitudes of students were same according to gender (p>0.05). Attitudes of university students studying at physiotherapy and rehabilitation department through WBDE regarding theoretical and applied courses were negative regardless of gender. This valid and reliable scale should be used to identify need of university students studying at applied sciences about WBDE. Advanced technology products should be urgently synchronized to WBDE.
Is there a relation between serum vitamin D and ovarian reserve markers in infertile women?: A retrospective cohort study
Authors: BEZİRGANOĞLU ALTUNTAŞ Neslihan , BAKİ YILDIRIM Sema , GÜVEY Huri , ERDEN Ömür
Published: September 2022

Vitamin D is an essential molecule for reproductive health. There are studies in the literature showing contradictory results regarding te relationship between serum 25(OH) vitamin D levels and ovarian reserve markers. The aim of this retrospective cohort study was to investigate the relationship between ovarian reserve markers; follicle stimulating hormone (FSH), antral follicle count (AFC), and anti-Müllerian hormone (AMH), and serum 25(OH) vitamin D levels. 195 infertil women aged between 18-45 years were included in the study. After the participants were divided into 2 groups according to their 25 (OH) D levels (those with < 20ng/ml (vitamin D deficiency) and those with ≥ 20ng/ml (vitamin D insufficiency)), the age, body mass index (BMI), AFC, AMH, FSH levels of the groups were compared. The mean age of the 25(OH) vitamin D deficient group was significantly younger (p=0.025) than the other group. There was no statistically significant difference in BMI (p=0.47) or season of blood sampling (p=0.62) between groups. The levels of the ovarian reserve markers AFC, AMH, and FSH were not significantly different between groups (p=0.95,0.18,0.86, respectively). Multiple linear regression and logistic regression analysis after adjusting potential confounders showed no significant relationship between vitamin D and AMH (p=0.628) and AFC(p=0.107). In conclusion, we found no correlation between 25(OH) vitamin D concentrations and markers of ovarian reserve. We cannot, however, ignore the critical role of vitamin D in the female reproductivity. To determine the optimal 25(OH)D3 levels during the reproductive period and the amount of vitamin D supplementation required to achieve those levels for the numerous actions of vitamin D throughout reproductivity process, high-quality, large-scale randomized clinical trials are required.
The effects of quarantine on postpartum depression, sleep quality and breastfeeding: Comparison of two different intensity period
Authors: GÜNKAYA Osman Samet , YAĞCIOĞLU YASSA Özge , TEKİN Arzu Bilge , TEKELİOĞLU Meltem , UMUR Göktuğ , ARSLAN Oğuz , GEDİK ÖZKÖSE Zeynep , KALKAN Üzeyir , TUĞ Niyazi
Published: September 2022

The aim of this study is to investigate the effects of quarantine/social isolation on maternal depression, breastfeeding and sleep quality in mothers who have just given birth during the pandemic period that has affected the whole world. This cross-sectional study included women who gave birth during either in the first peak of the first wave (April, 2020) or the end of the first peak (July, 2020) of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) pandemic in a tertiary pandemic regional referral centre. A total of 210 patients were enrolled to the study. The research data were collected using specific questionnaires including the Pittsburgh Sleep Quality Index (PSQI), the Edinburgh Postpartum Depression Scale (EPDS) and the Breastfeeding Self-Efficacy Scale-Short Form (BSES-SF). As a result, maternal postpartum depression and sleep quality scores did not differ significantly among postpartum women with different timelines according to the intensity of the SARS-CoV-2 pandemic (p=0.205 and p=0.352, respectively). The Breastfeeding Self-Efficacy Scale was significantly better (p=0.000) in the post-quarantine period than in the early stages of the pandemic when there were strict quarantine regulations. In conclusion, Sleep quality and postpartum depression remained unchanged with regard to the severity of the quarantine among women who gave birth during the SARS-CoV-2 pandemics. The breastfeeding self-efficacy of mothers was found as improved in the post-quarantine period.
Iron deficiency in women with thyroid-specific autoantibodies: A case control study
Authors: KOÇ Şanver , GÜNGÖR Kağan , DOKUZEYLÜL GÜNGÖR Nur , UZUNLULU Mehmet
Published: September 2022

Autoimmune thyroid diseases are multifaceted conditions in which the thyroid gland is infiltrated by lymphocytes, resulting in the production of thyroid-specific auto-antibodies against thyroid peroxidase (TPOAb) and thyroglobulin (TGAb). Iron deficiency is a common nutritional deficiency and has multiple adverse effects on thyroid metabolism. The association between iron status and thyroid autoimmunity has not been well-evaluated. This retrospective study aimed to determine whether the frequency of iron deficiency was higher in patients with thyroid autoimmunity than in healthy individuals with negative thyroid autoantibodies. One-hundred-and-eighty female patients with positive thyroid auto-antibodies and 81 healthy controls were involved in the study. Hemoglobin, hematocrit, mean corpuscular volume (MCV), iron, thyrotropin (TSH), TPOAb, TGAb, free-T4, vitamin B12, ferritin and transferrin saturation (TS) were recorded. TSH, TPOAb and TGAb levels were significantly higher, while hemoglobin, hematocrit, MCV, ferritin, iron and TS were significantly lower in the patient group (all, p<0.05). Patients with thyroid autoimmunity had significantly higher frequency of lower levels of hemoglobin, iron, ferritin, MCV and TS than healthy controls (all, p<0.005). Correlations were found inversely between TPOAb and serum ferritin, iron, and TS levels, and also positively between TGAb and creatinine levels in the patient group. In conclusion, we found increased prevalence of iron deficiency in female patients with thyroid autoimmunity. Patients with autoimmune thyroid diseases were found to be at higher risk of iron deficiency development.
Silymarin ameliorates cisplatin-induced nephrotoxicity by downregulating TNF-α and NF-kB and by upregulating IL-10
Authors: Altındağ Fikret
Published: September 2022

Cisplatin (CP) is one of the antineoplastic agents used to treat many types of cancers. Besides these effects of CP, it causes various side effects such as nephrotoxicity. Inflammation is considered to be one of the main pathogeneses of CP-induced nephrotoxicity. Silymarin (SIL) is a flavonoid with beneficial pharmacological properties such as antioxidant and anti-inflammatory. The current study aimed to investigate the beneficial effects of Silymarin against CP-induced nephrotoxicity. Albino Wistar male rats were randomly divided into four groups (n=7): Control group was administered saline (0.5 ml) for 10 days intraperitoneally (IP), CP group was received CP (a single dose of 8 mg/kg, IP), CP+ SIL group was administered saline (0.5 ml) for 10 days and was received CP (a single dose of 8 mg/kg). To measure the inflammatory response, TNF-α, NF-kB and IL-10 expressions were performed. As a result, TNF-α and NF-kB expressions significantly increased while IL-10 expression decreased in the kidney of the CP group compared to the control group. However, SIL treatment significantly decreased TNF-α and NF-kB expressions and increased IL-10 expression in kidney CP-treated rats. These findings reveal that SIL may ameliorates the CP-induced nephrotoxicity in rats by inducing downregulation of TNF-α and NF-kB expressions and upregulation of IL-10 expression.
The role of platelet mass index in the prediction of preeclampsia full
Authors: TAŞIN Cuma , KADIOGLU Nezaket , CİFTCİ Revan Sabri , COSKUN Ayhan , AYTAN Hakan
Published: September 2022

To assess the possible roles of platelet indices including platelet mass index (PMI), platelet count (PC), mean platelet volume (MPV) and PC/MPV in prediction of preeclampsia. 190 pregnant women diagnosed with preeclampsia and 100 healthy uncomplicated control patients were included in this retrospective study. Age, gestational week, fetal weight, alanine transaminase (ALT), aspartate transaminase (AST), creatinine, blood urea nitrogen (BUN), complete blood count parameters and platelet indices were compared. ROC curve was applied to analyze the cut-off values of the significantly differing parameters for prediction of preeclampsia. Preeclamptic patients gave birth significantly earlier than the controls. In preeclamptic patients, the mean values of PC, PC / MPV and PMI were significantly lower than the control group. Although mean MPV values were lower in preeclampsia patients, the difference was not significant. The cut-off values of PC, PC/MPV and PMI were found to be 207,500, 18448.16 and 2411.75 with a-sensitivity/specificity of 45.3%/ 44.3%, 42.2%/ 42.6% and 44.1%/ 44.3%, respectively. Indices such as PC, PC / MPV and PMI changed significantly in preeclampsia. Although they have low sensitivity and specificity, these indices can be combined with other parameters and used in the prediction of preeclampsia.
Do interventional pain procedures increase the risk of COVID-19?
Authors: KURÇALOĞLU Mustafa , APAK İbrahim , ŞENTÜRK Özgür , BİLEK Heval Can , UZUNER Bora , ÖZKAN Fatih , GÜLDOĞUŞ Fuat
Published: September 2022

This study's main aim was to evaluate the risk of COVID-19 in patients who were performed interventional pain procedures during the pandemic. The secondary aim was to evaluate if steroid injection in the procedures increases the risk of COVID-19. In this retrospective study, the records of patients who were performed interventional pain procedures (Group I) and were only examined (Group E) between the 1st of April and 30th of November 2020 were evaluated. The rate of COVID-19 infection in the first sixty days after the hospital visit was recorded. Results of patients who were injected steroids during the procedures were also evaluated. The records of 885 patients were investigated. While 485 of them were in Group I, 400 of them were in Group E. A total of 30 patients had COVID-19 in the assessment period. COVID-19 infection rates were similar between groups. Infection rates were not increased in patients who received steroids. The infection rate was significantly higher in the first 15 days after the hospital visit in both groups comparing the remaining 45 days. We conclude that neither interventional pain procedures nor single dose steroid injections increase the risk of COVID-19. However, ‘coming to hospital’ is a promoting factor itself. We assume that our results are also valid for all kinds of outpatient procedures. We suggest obeying the precaution recommendation guidelines of international communities during the pandemic.
Digital dental models in orthodontics: A review
Authors: AKDENİZ Berat Serdar , AYKAÇ Volkan , TURGUT Merve , ÇETİN Semanur
Published: September 2022

Digital 3 dimensional (3D) dental models are considered one of the most important advancements in modern dental history. Digital dental models are used in diagnosis, treatment planning, and appliance production phases in orthodontics. The present technology of digital dental models reached, and in some points, exceeded the plaster models' accuracy. The use of digital models with CBCT images and rapid prototyping techniques brought the possibility of new treatment techniques, some of which are considered as the future of modern orthodontics. This article aims to review the current use and success of digital 3D models in orthodontic practice.
Prognostic nutritional index predicts perioperative adverse events in patients undergoing hemiarthroplasty after a hip fracture
Authors: KILIÇ Cem Yalın , GÜRSAN Onur , AÇAN Ahmet Emrah , GÜLTAÇ Emre
Published: September 2022

The relation of the prognostic nutritional index (PNI) with perioperative adverse events (PE) has never been described in hip fracture surgery patients. Therefore, this study aimed to evaluate the impact of preoperative PNI on the outcome of patients undergoing hemiarthroplasty after a hip fracture. A total of 154 adult patients aged ≥ 65 years undergoing hemiarthroplasty after a hip fracture were included in this retrospective study. The outcomes of interest were the length of stay in hospital and PE during hospitalization, defined as death, surgical site infection, major bleeding, cardiopulmonary complications, acute renal failure, pneumonia, cerebrovascular accidents, and sepsis. PNI was calculated from the following formula: 10 × serum albumin (g/dL) + 0.005 × total lymphocyte count (per mm3). Patients’ information, including demographic data, routine preoperative laboratory tests, and PNI, was collected to assess the association between these factors and the PE. Perioperative adverse events occurred in 21 (13.6%) of the patients. Older patients and those with more comorbid conditions such as heart failure, coronary artery disease, diabetes mellitus, cerebrovascular diseases, and chronic obstructive pulmonary diseases were tended to have a higher rate of PE. Patients with PE had lower PNI (45.2±4.2 vs. 51.6±5.4; p < 0.001) on admission. Multivariate analysis showed that age (OR: 2.23, 95% CI 1.15-4.45, p=0.042), presence of diabetes (OR: 2.34; 95% CI: 1.74–6.89; p =0.005) and PNI < 47.2 (OR 2.54, 95% CI 1.32-5.72, p = 0.004) were signiﬁcant and independent predictors of PE. This study is the first to demonstrate that the lower preoperative PNI is associated with PE in patients undergoing hip fracture surgery.
Multiorgan failure due to strongyloides infection in liver transplant recipient: A case report and literature review
Authors: EKMEN Nergiz , BİLGER Nirgül , KİRMAN Derya , SASANİ Hadi
Published: September 2022

Strongyloidasis is caused by an intestinal nematode Strongyloides stercoralis which is widely distributed in tropical and subtropical countries. In immunocompetent individuals, Strongloides stercoralis infection usually does not produce any symptoms or causes gastrointestinal, cardiopulmonary, or skin symptoms. However, in some patients especially immunsupressive (e.g post-transplant, taking exogenous corticosteroids), its infection associated with severe and life-threatening disease like hyperinfection syndrome and disseminated tissue infestation. The limitation of diagnostic test make it challenging to diagnose strongyloidasis. Therefore, it is important to suspect infection of Strongyloides stercoralis. We describe a case of Strongiloides infection with a fatal outcome in liver transplant recipient.
Knotted nasogastric catheter
Authors: ÖZKAN Abuzer , ÖZDEMİR Serdar
Published: September 2022

A 64-year-old male patient called the emergency medical service with complaints of respiratory distress and high fever. He was brought to our clinic by the emergency medical service by ambulance. In the ambulance, ventilation was performed with a balloon mask for 10 minutes due to hypoxia. With balloon mask ventilation, his saturation was 70. endotracheal intubation was performed. The patient with a history of coronary artery disease was using 100 mg acetylsalicylic acid per day. It was learned from his anamnesis that the patient, who had cough and high fever for 3 days, had respiratory distress for one day. Vital parameters after intubation were arterial blood pressure 65/40 mmHg, pulse 96/minute, and temperature 38.3 ° C. On physical examination, Glasgow coma score was 5 (E1, M2, V2). There was widespread crackles in the right lung to the respiratory examination. There was distension in the abdominal examination. Among the laboratory parameters, leukocyte was measured as 18 000/µl, neutrophil as 10 500/µL, C-reactive protein as 81 mg/L. Other hematological and biochemical parameters were normal. Computed tomography of the thorax showed extensive consolidation and air bronchograms on the right lung. Empirical antibiotic therapy was initiated. During the nasogastric catheter application, it was noticed whether the tube encountered resistance and not progressed. When the tube was pulled out, it did not come. It was found that the end of the tube formed a very interesting knot when the oropharynx was controlled and pulled through the mouth with the help of a forceps (Figure 1-2). Nasogastric catheter (NGS) is used for purposes such as cleaning out the contents of the stomach, preventing aspiration in unconscious patient and providing nutrition (1). Complications may be encountered in nasogastric tube applications (2). Knotting of the tube is a rare condition that may be encountered. It should be considered when resistance is encountered in advancing or withdrawing the nasogastric tube.
Effects of ketogenic and western diets on proliferation, vasculogenesis and oxidative stress in the liver
Authors: DOĞANAY Songül , BUDAK Özcan , BAHTİYAR Nuretn , TOPRAK Veysel
Published: September 2022

In this study, it was aimed to investigate the effects of different diets on lipid peroxidation, antioxidants, proliferation and vasculogenesis in liver tissue. BALBC female rats (21) were divided as the group fed with standard chow (SC), the group fed with a ketogenic diet (KD) and the group fed with western diet (WD). The rats were fed with tap water and a rat diet specially prepared according to the determined diets for four weeks. Liver tissue oxidative damage, proliferation and vasculogenesis were evaluated using spectrophotometric and immunohistopathological methods. At the end of the experiment, it was found that the highest weight gain was in the WD group and the least weight gain was in the KD group. The mean body weight of the WD group was statistically significantly higher compared to the SC and KD groups (p<0.05). MDA levels were found to be lower in the KD group compared to the SC and WD groups. GSH and CAT levels were higher in the KD group compared to the SC and WD groups. In IHC evaluation results, it was seen that Ki-67 percentage in the KD group increased compared to the WD and SC groups (p = 0.000), VEGF was close to each other in all three groups and there was no significant difference in the comparisons between groups (p>0.05). These results revealed that ketogenic diet prevents tissue damage by decreasing lipid peroxidation in liver tissue as well as inducing cellular proliferation and vasculogenesis.
Effects of curcumin on arginase enzyme activity, ornithine and nitric oxide levels in experimental breast cancer model
Authors: KÜRKÇÜ KAHRAMAN Ezgi , AYDOĞDU Nurettin , ERBAŞ Hakan
Published: September 2022

Breast cancer accounts for almost 30% of all cancer types, making it the most common type of tumor among women in the world. Arginase, an essential enzyme of the urea cycle, leads to the formation of urea and ornithine from L-arginine using the same substrate as nitric oxide synthase (NOS). Arginase has been reported to be higher in cancer patients and can be used as a useful biomarker. In this study, we aimed to investigate the effects of curcumin, an anticarcinogenic agent, on arginase enzyme activity, ornithine, and nitric oxide (NO) levels in experimental breast cancer model in mice. 43 male Balb/c mice were used, and Erhlich acid tumor model was created in the study. Mice were divided into five groups as healthy control group, curcumin treatment before tumor formation, curcumin treatment after tumor formation and cancer control groups. 100 mg/kg curcumin were given orally. Serum and tissue arginase enzyme activities, NO levels and tissue ornithine levels were determined spectrophotometrically. Increased serum arginase activity decreased with curcumin treatment, but this difference was not statistically significant. On the other hand, decreased NO levels were increased with curcumin treatment. In tumor tissue, arginase activity and ornithine levels decreased significantly with curcumin treatment and tissue NO levels increased significantly with curcumin treatment. In our study, we show that curcumin may have a protective effect on the development of breast cancer by inhibiting arginase enzyme activity and ornithine levels, which are the precursors of polyamines, as well as inducing NO production via NOS. As a promising anticancer agent, the net effects of curcumin in this mechanism should be supported by more advanced studies and new parameters.
A Brief Review on Isoxazole Derivatives as Antibacterial Agents
Authors: V S Anila Kumari , G R Dr. Prasobh , A G Sheeja Rekha
Published: September 2022

Isoxazole compounds exhibit a wide spectrum of targets and broad biological activities. Isoxazole derivatives are still popular scaffolds for the development of new agents with variable biological activities such as antimicrobial, antiviral, anticancer, anti-inflammatory, immunomodulatory, anticonvulsant or antidiabetic properties. The key feature of these heterocycles is that they possess the typical properties of an aromatic system but contain a weak nitrogen-oxygen bond which under certain reaction conditions like reducing or basic conditions is a potential site of ring cleavage. Thus, isoxazoles are very useful intermediates since the ring system stability allows the manipulation of substituents to give functionally complex derivatives, yet it is easily cleaved when necessary. In this review we have focused on the FDA approved antibacterial agents, clinically used drugs containing isoxazole moiety, Antibacterial agents with isoxazole moiety under preclinical trial, Isoxazole derivatives as antibacterial agents, FDA approved antibacterial agents with isoxazole ring, Mechanism of action of isoxazole derivatives, synthesis and screening of isoxazole derivatives as antibacterial agents

Keywords: Isoxazole, Antibacterial activity, FDA approval, Chalcone
A Survey on Online Computer Practicum during the COVID-19 Pandemic: Students’ Perceptions
Authors: Sutrisno Sutrisno , Lubis Andre Hasudungan
Published: September 2022

The COVID-19 pandemic requires all of the educational institution to organize the online learning due to social distancing policy. The online computer practicum is the one method to comply the online learning during the pandemic. The study conducted a survey to scrutinize the students’ perceptions on the online computer practicum implementation in three perspectives: acceptance, satisfaction, and knowledge comprehension. A total 1155 students are selected as the respondent and the descriptive statistical analysis is employed as the means to analysing data. The findings show that students are satisfied and accepted the technology use. The knowledge transfer also runs properly from the instructor to students even it was hold by online.

Keywords: Online Learning, Computer Practicum, Acceptance, Satisfaction, Knowledge.
Design of a Hydroponic Smart Farm System with Web-Based IoT in Bireuen Regency
Authors: Fajri T. Irfan , . Mustaqim , . Rahmad
Published: September 2022

The development of science and technology is growing so rapidly that it encourages people to continue to think with the aim of finding solutions to existing problems so as to help with daily work. One of them is the use of controlling and monitoring systems for agricultural cultivation land. The research aims to understand design of a hydroponic smart farm system with web-based internet of things (IoT) in Bireuen Regency. This research is carried out from August to September 2022. This section describes the concept of hydroponic system design with IoT and observation techniques to see how far the process of implementing IoT is implemented in hydroponic plants. The results show that the system can find out and display data obtained from several sensors that have been installed on hydroponic plants, such as light sensors, Ph sensors, and DTS sensors. This system can also be used to control or control a four-channel relay that is used to control several actuators installed, such as 1 water pump, 2 fertilizer pumps, fans, and lights via the website. Even this system has an additional command that is used to control the relay by utilizing the website.

Keywords: Hydroponic, Smart Farm System, Internet of Things
A Mismanaged Case of Hypophosphatemic Rickets
Authors: Varuna Sugha , Sapna Bharti
Published: September 2022

X-linked hypophosphatemic rickets is a common cause of inherited hypophosphatemia and is caused by mutation in the PHEX gene, resulting in excessive expression of FGF23 which causes phosphaturia. Due to its rarity, X linked hypophosphatemic rickets is poorly known and diagnosis is frequently delayed. Conventional treatment is based on oral phosphate salts supplementation and activated vitamin D analogs, which however, cannot cure the disease in most cases.

Keywords: X linked hypophosphatemic rickets, FGF23, PTH
Anti-Inflammatory Effectiveness of Sungkai Leaf Extract (Peronema Canescens) Against Lung Histopathological Appearance, Polymorphonuclear Cell (PMN) Number, and Macrophages in Inflammatory Model Mice with Covid-19 Vaccine Induction
Authors: Abeiasa M. Saka , Humaira Vilma
Published: September 2022

Inflammation of the respiratory tract can occur when the respiratory tract tissue, especially the lungs, is injured, infected with bacteria and viruses, exposed to toxins, or heat. In the case of Covid-19 sufferers, when the virus first enters the body, macrophage cells will respond by producing cytokines to the infected tissue. One type of plant that can be used as an alternative treatment for inflammatory symptoms is the sungkai plant. Flavonoid compounds, saponins, alkaloids and phenols have anti-inflammatory activity. Where the content of secondary metabolites, tannins and flavonoids has activity as an antioxidant so that it can prevent damage due to oxidative stress. This type of research is an experimental laboratory research with a posttest group only design where the test is carried out at the end of the treatment period to see the relationship between the independent variables, namely the administration of sungkai leaf extract at graded doses to the independent variables in the form of pulmonary histopathology, the number of polymorphonuclear cells (PMN), and mouse macrophage (ratus norvegicus) inflammatory model by induction of covid-19 vaccine. Based on the One way ANOVA test, it was found that there was a significant effect of multi-dose sungkai leaf extract on the infiltration of lung inflammatory cells (p value 0.00), the number of polymorphonucleates (p value 0.00) and the number of macrophages (p value 0.00). The conclusion in this study was that the administration of multi-dose sungkai leaf extract had an anti-inflammatory effect which was reflected in the number of histopathological inflammatory cell infiltrates, the number of polymorphonuclear cells, and macrophages.

Keywords: Sungkai Leaf; Pulmonary Histopathology; PMN cells; macrophages; Experimental Animals;
Pneumoperitoneum, retropneumoperitoneum and pneumomediastinum after stapled hemorrhoidopexy
Authors: Da Silva Pinto Danielle , Moraes Paro Anna Clara , Yuji Tanaka Daniel , Oliveira Johnen Ana Carla , Guimenti Ribeiro de Lima Pedro , Dias Muniz de Andrade Izabella , Regina de Souza Marini Amanda , Schleinstein Henrique Perobelli , Gentile João Kleber de
Published: September 2022

There are several surgical techniques for the treatment of hemorrhoidal disease, the most used currently being stapled hemorrhoidopexy. Complications of this procedure are rare, although they may occur. The aim of this study is to report the clinical case of a patient with severe complication of rectal perforation after stapled hemorrhoidopexy. A 44-year-old man who presented anal pain in his postoperative period of hemorrhoid with urgent computed tomography evidencing rectal perforation with pneumoperitoneum, retropneumo-peritoneum and pneumomediastinum. Rectal perforation is a specific complication of surgery using stapler. One of the serious consequences is pneumoperitoneum, whose air leaked through the rupture of the rectal wall can reach the mediastinum, causing pneumomediastinum. These complications can be avoided by taking care of the triggering of the stapler device, in addition to post-surgical evaluation, such as rectal exploration before discharge.
Euro adoption obliged countries viewed by Melitz Optimum Currency Area model
Authors: Bednar Ondrej
Published: September 2022

Empirically applied alternative Optimum Currency Area theory model proposed by J. Mélitz. We calculated trade-weighted terms of trade covariance of several European countries bound to become Eurozone members. The higher the covariance, the higher the cost of joining the Eurozone. Considering the openness index and nominal rigidities, we ordered the countries by the (dis)advantage of joining the Eurozone. According to the model, the highest cost of joining the currency block is attributed to Croatia as its trade partners have high covariance of terms of trade. Croatia is also not as open as other countries like the Czech Republic or Hungary, showing relatively higher nominal rigidity. On the other hand, Bulgaria appears to profit from adopting the Euro the most.
A World Café Approach for Maker Education Context into the Internet of Things Course
Authors: Po-Sheng Chiu Po-Sheng Chiu
Published: September 2022

In recent years, Makerspaces research is growing by maker movement, Makerspace provides a learning environment to help students learning maker education. Especially, the World Cafe focuses on sharing and exploring ideas, and participants are able to express their views. However, no previous research using meaningful learning to investigated The World Café method in Makerspace learning environment to understand the educational potential of this study. This study aims to investigate gender difference and The World Café method impact students’ learning achievement and meaningful learning in maker education. This study used one-group pretest-posttest nonequivalent-groups design method, and consisted of 53 college students that take the course and then complete the questionnaire before and after The World Café method. The results showed that improved students’ learning achievement and meaningful learning in The World Café method, and male have positive learning achievement, but meaningful learning questionnaire showed that the gender difference didn’t reach significance in The World Café method. This study revealed that The World Café method might be appropriate for the needs of learning by doing subjects and future research could continue to explore more STEM/maker education.

 
UAV-Enabled Mobile Edge Computing with Binary Computation Offloading and Energy Constraints
Authors: Changyuan Xu Changyuan Xu , Changyuan Xu Cheng Zhan , Cheng Zhan Jingrui Liao , Jingrui Liao Bin Zeng
Published: September 2022

Mobile edge computing (MEC) has been considered to provide computation services near the edge of mobile networks, while the unmanned aerial vehicle (UAV) is becoming an important integrated component to extend service coverage. In this paper, we consider a UAV-enabled MEC with binary computation offloading and energy constraints, where an energy-limited UAV is employed as an aerial edge server and each task of devices is either executing locally or offloading to the aerial edge server as a whole. To provide fairness among different ground devices, we aim to maximize the minimum computation throughput among all devices via the joint design of computing mode selection and UAV trajectory as well as resource allocation. The optimization problem is formulated as a mixed-integer non-linear problem consisting of binary variables, which is difficult to tackle. By employing deductive penalty function to penalize the effect of non-binary solution, we develop an efficient iterative algorithm to obtain a suboptimal solution via leveraging the penalty successive convex approximation (P-SCA) method and difference of two convex (D.C.) optimization framework, where the algorithm is guaranteed to converge. Extensive simulations are conducted and the results with different system parameters show that the proposed joint design algorithm can improve the computation throughput by about 40% compared to other benchmark schemes.

 
A Social Network Analysis of COVID-19 Transmission Models in Taiwan: Two Epidemic Waves in 2020-2021
Authors: Pei-Hsuan Hsieh Pei-Hsuan Hsieh , Pei-Hsuan Hsieh Chun-Hua Lin
Published: September 2022

The COVID-19 pandemic has made a profound global impact. As it rages on around the globe, social network researchers have been involved in exploring key factors of rapid infection and transmission. For Taiwan, it is thus worthy of exploring the differences between the transmission models of the two epidemic waves in 2020-2021 for any insight that may have been overlooked. In this study, the social network analysis is adopted for revealing any unforeseen threats of infection. In the first wave, 652 confirmed cases were reported from January 21, 2020, to November 30, 2020. In the second wave, 880 confirmed cases were reported from May 03, 2021, to May 17, 2021. The infection source attribute, i.e., local vs. imported, made the transmission models to be structured differently between the first and the second wave. In the first wave, it was found that a community outbreak could easily happen when one node got infected without knowing when and where the transmission occurred. In contrast, in the second wave, it was found that the gender attribute was more effective than the age attribute in quickly identifying the differences in the transmission models among all the confirmed cases.

 
Effective Radio Resource Allocation for IoT Random Access by Using Reinforcement Learning
Authors: Yen-Wen Chen Yen-Wen Chen , Yen-Wen Chen Ji-Zheng You
Published: September 2022

Emerging intelligent and highly interactive services result in the mass deployment of internet of things (IoT) devices. They are dominating wireless communication networks compared to human-held devices. Random access performance is one of the most critical issues in providing quick responses to various IoT services. In addition to the anchor carrier, the non-anchor carrier can be flexibly allocated to support the random access procedure in release 14 of the 3rd generation partnership project. However, arranging more non-anchor carriers for the use of random access will squeeze the data transmission bandwidth in a narrowband physical uplink shared channel. In this paper, we propose the prediction-based random access resource allocation (PRARA) scheme to properly allocated the non-anchor carrier by applying reinforcement learning. The simulation results show that the proposed PRARA can improve the random access performance and effectively use the radio resource compared to the rule-based scheme.

 
A Study on House Price Prediction Based on Stacking-Sorted-Weighted-Ensemble Model
Authors: Zhentao Li Zhentao Li , Zhentao Li Shiyi Xie , Shiyi Xie Ying Zhang , Ying Zhang Jie Hu
Published: September 2022

The house price prediction problem is a typical regression problem, and most of the common house price prediction models are single prediction algorithms, which are not ideal in terms of accuracy and stability. For solving this problem, this paper proposes a house price forecasting method based on Stacking-Sorted-Weighted-Ensemble (SSWE) model. Considering the characteristics of different algorithms and giving full play to the advantages of each model, multiple individual forecasting models are fused with the Stacking model. The algorithm validation is performed using the data generated by the system of real estate management department in western Guangdong. The prediction results show that the Stacking model is superior to the single model. Compared with the Stacking regression model, the SSWE model has a 13.6% increase in the root mean square error on the training set but a 0.3% decrease on the test set, indicating that the SSWE model prevents overfitting to a some extent and increases the accuracy and stability of the model.

 
探討稀缺性對消費者購買意願與認知失調之影響-以從眾效應為中介效果
Authors: 鄭淑勻 鄭淑勻 , 余梅香 余梅香
Published: September 2022

現今人們因工時增加而導致休閒時間減少，購物變成重要的休閒娛樂。消費者在購物時，除了需求上的滿足，想要展現自我與眾不同的需求也越來越高，常以購物來展現自我。稀缺性產品的消息會比非稀缺性產品有著更加良好的傳播效果。可得知稀缺性可以做為刺激消費者在網路購物決策過程的一項有效工具，因此許多業者開始利用稀缺性作為他們的銷售手法來吸引顧客。「稀缺推廣」是實務上常用的行銷策略，本研究以供給性稀缺為基礎，探討消費者受到從眾效應之影響進而改變自身的購買決策之可能性，而在購買產品後是否會因結果不如預期而產生購後認知失調。

本研究以問卷調查法為研究工具，問卷計分採用李克特 ( Likert-scale ) 五點尺度量表作為計算方式，將主要研究對象設定在有購買過限量性產品的消費者，共發出274份，刪除有亂填跡象與無購買過稀缺性產品之無效樣本72份後，有效問卷總共為202份，問卷有效率為74%。本研究透過信度分析、敘述性統計分析、獨立樣本T檢定、單因子變異數分析及迴歸分析得出以下結果：（1）稀缺性會正向影響產品的購買意願；（2）從眾效應在稀缺性與購買意願上具有中介效果；（3）從眾效應會正向影響產品的購買意願；（4）從眾效應會正向影響購後認知失調；（5）稀缺性對認知失調不具顯著正向影響。並依據研究結果提出實務建議供業者參考。

 

Shopping is now one of the most popular leisure activities in this era. People with a high need for uniqueness are more eager to obtain commodities that are different from others, thus showing their uniqueness. Information of scare products will have a better spread effect than non-scarce products. Marketers frequently use scarcity promotions, where a product is limited in availability, as a marketing tactic to enhance customer shopping decision and purchase willingness. Based on the scarcity of supply, this study seeks to examine how scarcity appeal affects consumer purchase intention and to examine their post-purchase cognitive dissonance as well. Quantitative analysis and convenience sampling were used to survey consumers who have purchased limited-edition products. 202 valid online questionnaires were obtained, and the study used descriptive statistics, and regression analysis to test hypotheses and to examine the mediating effect of conformity effect. The results indicate that:1. Scarcity has a positive effect on consumer purchase intention;2. Conformity effect mediates the relationship between scarcity and purchase intention;3. Conformity effect is positively related to purchase intention;4. Conformity effect will positively affect post-purchase cognitive dissonance; 5. Scarcity has no significant effect on post-purchase cognitive dissonance.

 
農會導入行動科技之決策評估模式
Authors: 周建亨 周建亨 , Chien-Heng Chou 施光訓 , Kuang-Husn Shih 謝建達
Published: September 2022

數位轉型為我國政府推動的六大核心戰略之一，農會必須要思考如何有效善用新興科技進行數位轉型，提高經營績效與服務品質，補強人口高齡化及外移所出現的勞動力缺口。爰此，農會要如何有效導入行動科技至組織中，促進農會數位轉型的關鍵成功因素是什麼，成為本研究動機之一。回顧過去研究，探討農會轉型的主題多採用員工的問卷調查，但缺少對農會經營者的想法，此為本研究機動之二。爰此，為探討農會導入行動科技應用之決策準則，本研究結合決策實驗室分析法（Decision Making Trial and Evaluation. Laboratory, DEMATEL）與網路分析程序法（Analytic Network Process, ANP），建立農會數位轉型之決策架構，分析結果可作為農會決策者規劃經營策略及分配資源之重要參考依據。

 

Digital transformation is one of the six core strategies in Taiwan. Farmers’ associations must consider how to effectively introduce emerging technologies to carry out digital transformation, improve business performance and service quality, and fill the labor gap caused by an aging population and out-migration. Therefore, how to effectively introduce mobile technology into the organization and what are the key success factors to promote the digital transformation of the farmers’ association have become one of the motivations of this study. Reviewing previous studies, the topic of discussion on the transformation of farmers’ associations mostly uses questionnaires from employees, but there is a lack of ideas for operators of farmers’ associations, which is the second motivation of this study. In order to discuss how the farmers’ association can effectively introduce mobile technology, this study combined the Decision Making Trial and Evaluation Laboratory (DEMATEL) and the Analytic Network Process (ANP) to establish a decision-making evaluation framework for the digital transformation of farmers’ associations. The results can be used as an important reference for managers to plan business strategies and allocate resources.

 
Implantação da escala Munro de avaliação de risco de lesão por pressão no perioperatório
Authors: Sousa Cristina Silva , Acunã Andrea Alfaya
Published: September 2022

Objetivo: Descrever a implantação da escala Munro de avaliação de risco de lesão por pressão em pacientes no período perioperatório no prontuário eletrônico. Método: Relato de experiência do processo de implantação em sistema eletrônico da escala Munro em um hospital filantrópico de grande porte localizado no município de São Paulo, com 40 enfermeiros. Resultados: Foi implantada a escala Munro no prontuário eletrônico, com visualização rápida do seu resultado em alertas de segurança em painel do mapa cirúrgico. Para utilizar a técnica, 40 enfermeiros foram treinados em duas etapas: na modalidade ensino a distância e presencialmente, quando acompanharam sua aplicação. Três desses profissionais necessitaram de mais um dia de acompanhamento e cinco apresentaram dúvidas quanto aos critérios de aplicabilidade após o treinamento. Conclusão: A implantação da escala Munro foi concluída na unidade primária proposta, a determinação de risco sistematizada e a implementação de medidas preventivas contribuiu para evitar lesões por pressão no perioperatório. O sistema eletrônico proporcionou agilidade para implantação, e os alertas e a visualização em mapa cirúrgico melhoraram a comunicação com a equipe na identificação do risco; poucas foram as dúvidas sobre o processo ou itens da escala.
Auch Paradigmen entwicklen sich
Authors: Bots Ursula
Published: September 2022

Das Buch Entwicklungsorientierte Bildung – ein Paradigmenwechsel befasst sich mit der Orientierung und Ausrichtung der Paradigmen in der Bildung. Der Lehrplan 21 der Schweizer Volksschulen sowie das ECTS-Bologna-System orientieren sich aktuell an der Kompetenzorientierung. Das Buch beschäftigt sich mit der Frage, welches Pa­ra­digma dieser Kompetenzorientierung folgen könnte. Dabei wird die Hypothese aufgestellt, dass die vormalige Wissensorientierung und die jetzt geltende Kompetenzorientierung als wich­tige Stationen verstanden werden, denen als eine nächste Station die Entwicklungsorientierung folgen könnte.
Voneinander lernen: innovative Ideen vor den Vorhang!
Authors: Heißenberger Petra
Published: September 2022

Jakob Calice ist Geschäftsführer des OeAD, Österreichs Agentur für Bildung und Internationalisierung. Er ist Vorstand der Innovationsstiftung für Bil­dung, die als Impulsgeber für die Zukunft der Bildung fungiert. Er war viele Jah­re in den Bereichen der Forschungs- und Wissenschaftspolitik sowie der Bil­dung tätig, zuletzt im Bundesministerium für Bildung, Wissenschaft und For­schung als Generalsekretär. Als Experte in Bildungs- und Wis­sen­schafts­politik berichtet er von Konzepten innovativer österreichischer Schulen.
EKONOMİK BÜYÜME, DOĞRUDAN YABANCI SERMAYE YATIRIMLARI, FİNANSAL GELİŞME VE EKOLOJİK AYAK İZİ ARASINDAKİ İLİŞKİ: ABD VE ÇİN ÜZERİNE BİR ANALİZ
Authors: BAKKAL Hakan
Published: September 2022

Bu çalışma, ekonomik büyüme, doğrudan yabancı sermaye yatırımları ve finansal gelişmenin çevresel bozulmadaki etkisini belirleme amacını taşımaktadır. Bu amaçla, ekonomik faaliyetler karşılığında çevre tüketiminin yüksek olduğu, tüm ülkeler içerisinde en büyük ekonomik güce sahip olan ABD ve Çin’de seçilmiş ekonomik değişkenler ile ekolojik ayak izi arasındaki ilişki incelenmektedir. Ampirik sonuçlara göre, ABD ve Çin’de ekonomik büyüme ve finansal gelişme çevresel bozulmayı artırmakta, doğrudan yabancı sermaye yatırımları ise çevre kalitesine katkıda bulunmaktadır. Bununla birlikte, ekonomik büyümenin çevre üzerindeki olumsuz etkisi ve doğrudan yabancı sermaye yatırımlarının olumlu etkisi Çin’e göre ABD’de daha fazladır. Nedensellik test sonuçları ekonomik büyüme ve finansal gelişme ile ekolojik ayak izi arasındaki bu ilişkiyi ABD için desteklemektedir. Elde edilen bulgular, üretimde daha fazla çevre dostu teknolojileri ve yenilenebilir enerji kaynaklarının kullanımının küresel boyutta sürdürülebilir büyümeye önemli katkı sağlayacağını göstermektedir.
Docência, formação de professores e práticas pedagógicas: orientação para o desenvolvimento da prática docente – (uma análise conceitual)
Authors: Dantas Hildeci de Souza
Published: September 2022

O presente estudo é de natureza qualitativa e conceitual e advoga um recorte básico da tese doutoral do pesquisador em educação entre o ano de 2017 e 2019 acerca de pesquisa na temática: “formação de professores e o desenvolvimento das práticas pedagógicas”, isto é, tendo como o estado da arte a “docência” e sua orientação para a “prática docente”. O trabalho em si alinha-se por uma abordagem qualitativa e seu viés conceitual é respaldado no capítulo VI intitulado como discussões e resultados, em especial, o apêndice VII com enfoque para a “docência e práticas educativas” de modo bibliográfico. A pesquisa se mostrou pertinente quando da amostragem A e B do curso em investigação, sendo que os fundamentos teóricos, didático-pedagógicos bem como o entorno da docência e sua prática educativa foram peças-chave para a orientação e o desenvolvimento da prática pedagógica. Resumidamente, avalia-se que o aporte-chave dessa prática docente se fez equivalente ao próprio contexto da docência uma vez que a formação docente é a dinâmica para a formação do futuro pedagogo e sua prática se desvela para o êxito da docência e do ensino.