bluuebunny/crossref_metadata_2025 huggingface dataset:
Hubungan Tingkat Pengetahuan dengan Perilaku Keselamatan Berkendara pada Pengendara Ojek Online di Kota Depok Tahun 2022
Authors: Fanny Mochammad Fanny , Romdhona Nur
Published: September 2023

Jawa Barat berada pada urutan ketiga terterbesar dari total kecelakaan dan korban jiwa se Indonesia. Berdasarkan hasil observasi, pengendara sepeda motor di daerah jalan Depok terutama ruas jalan Margonda, UI, dan Raya Bogor mayoritas memiliki perilaku safety riding yang kurang dan tergolong agresif. Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan pengetahuan dengan perilaku keselamatan berkendara pada pengendara ojek online. Penelitian ini adalah penelitian kuantitaif observasional dengan desain studi cross-sectional, penelitian ini dilakukan di Kota Depok. Populasi adalah seluruh pengendara ojek online di Kota Depok. Sampel sebanyak 120 responden denga teknik quota sampling. Data kemudian dianalisis secara bivariate dengan uji chi-square. Hasil penelitian: menunjukan perilaku keselamatan berkendara aman sebanyak 50,8%. Terdapat hubungan yang bermakna antara pengetahuan (nilai p=0,0001; OR=2,3; CI=1,8-2,8). Sebagian besar ojek online di Kota Depok memiliki tingkat pengetahuan keselamatan berkendara yang baik, yaitu sebanyak 107 pengendara (89.2%) dari 120 pengendara. Perlu upaya meningkatkan perilaku keselamatan pengendara ojek online dengan berbagai pelatihan dan pengetahuan di Kota Depok untuk meminimalisir perilaku keselamatan berkendara yang tidak aman pada pengendara ojek online.---West Java is the third largest number of accidents and fatalities in Indonesia. Based on observations, motorcycle riders in the Depok road area, especially the Margonda, UI, and Raya Bogor roads, the majority have less safety riding behavior and are classified as aggressive. Objective: This study aims to determine the relationship between knowledge and driving safety behavior of online motorcycle taxi drivers. This research is an observational quantitative study with a cross-sectional study design, this research was conducted in Depok City. The population is all online motorcycle taxi drivers in Depok City. The sample is 120 respondents with quota sampling technique. The data were then analyzed bivariately with the chi-square test. The results of the study: showed safe driving safety behavior as much as 50.8%. There is a significant relationship between knowledge (p value = 0.0001; OR = 2.3; CI = 1.8-2.8). Most of the online motorcycle taxis in Depok City have a good level of knowledge of driving safety, as many as 107 riders (89.2%) out of 120 riders. Efforts are needed to improve the safety behavior of online motorcycle taxi drivers with various training and knowledge in Depok City to minimize unsafe driving safety behavior for online motorcycle taxi drivers.
Pengaruh Ikan Kembung (Rastrelliger) Terhadap Berat Janin Pada Tikus Putih Betina (Rattus Norvegicus) Anemia
Authors: Nugroho Setyo Mahanani , Nurtyas Maratusholikhah
Published: September 2023

Kebutuhan nutrisi pada kehamilan bertambah dua kali lipat sehingga asupan gizi juga bertambah. Kurangnya asupan gizi dapat menyebabkan wanita hamil mengalami anemia. Selain itu juga beresiko pada janin yaitu pertumbuhan terhambat, prematuritas, kemungkinan bayi lahir cacat bawaan, serta kematian. Tujuan penelitian ini adalah untuk mengetahui Pengaruh Ikan Kembung (Rastrelliger) terhadap Berat Janin pada Tikus Putih Betina (Rattus Norvegicus) Anemia. Metode penelitian menggunakan jenis penelitian eksperimental laboratorik yang menggunakan rancangan acak lengkap dengan menggunakan pola post test only control group design. Hasil Uji Normalitas Data Shapiro-Wilk menunjukkan nilai p-value yang semuanya lebih besar dari taraf signifikansi  α = 0,05 sehingga dapat disimpulkan data telah terdistribusi normal. Hasil Uji One Way Anova menunjukkan Fhitung > Fkritis. Sehingga dapat disimpulkan terdapat pengaruh ikan kembung (Rastrelliger) terhadap berat janin pada tikus putih betina (Rattus Norvegicus) anemia.---Nutritional needs in pregnancy are doubled so that nutritional intake also increases. Lack of nutritional intake can cause pregnant women to experience anemia. In addition, there are also risks to the fetus, namely stunted growth, prematurity, the possibility of the baby being born with congenital defects, and death. The purpose of this study was to determine the effect of puffer fish (Rastrelliger) on fetal weight in anemic female white rats (Rattus norvegicus). The research method uses a laboratory experimental research type that uses a completely randomized design using a post test only control group design pattern. The results of the Shapiro-Wilk Data Normality Test show that all p-values are greater than the significance level of = 0.05 so that it can be concluded that the data has been normally distributed. The One Way Anova test results show Fcount > Fcritical. So it can be concluded that there is an effect of mackerel (Rastrelliger) on fetal weight in anemic female white rats (Rattus norvegicus).
Keluhan Muskuloskeletal Ektremitas atas Berdasarkan Metode Rapid Upper Limb Assessment (RULA) pada Pekerja Bagian Produksi Pt Panca Karya Unggul Abadi (PKUA)
Authors: Listyowati Wiwin , Naiem Muhammad Furqaan , Baktiansyah Abdul , Deli Aragar Putri
Published: September 2023

Menurut data labor force survey UK, angka kejadian muskuloskeletal pekerja masih terlampau besar dengan jumlah kasus sebanyak 1.144 juta kejadian. Hasil studipendahuluan menyatakan bahwa 5 dari 7 pekerja pada operator mesin cutting di bagian produksi PT. PKUA mendapatkan nilai hasil akhir assessment adalah 7, sehingga pentingnya peneleitian ini dilakukan guna memberikan rekomendasi spesifik untuk menurunkan nilai akhir assessment RULA pada seluruh tim produksi. Menentukan Gambaran Keluhan Muskuloskeletal Ekstremitas Atas pada pekerja di bagian produksi berdasarkan metode RULA pada pekerja di bagian produksi di PT PKUA Bogor Jawa Barat. Penelitian observasional deskriptif dangan sampel 27 orang menggunakan sampel jenuh. Analisis yang digunakan adalah analisis univariat dan analisis Metode derajat RULA. Mayoritas responden berumur 25-34 tahun dengan jumlah 12 orang (44,4%), Sementara untuk tingkat pendidikan rmayoritas responden memiliki tingkat pendidikan SMK/SMA yaitu 23 orang (85,1%). Sebagian besar responden penelitian ini memiliki masa kerja ≥3 tahun sebanyak 18 orang (66,7%). Hasil akhir penelinaian RULA menyatakan responden memiliki level keluhan 5-6 yaitu sebanyak 19 orang (70,4%), lalu diikuti oleh kelompok responden dengan level keluhan ≥7 yaitu sebanyak6 orang (22,3%) dan level keluhan 3-4 yaitu sebanyak 2 orang (7,4%). Mayoritas pekerja pada tim produksi di PT. PKUA memiliki level keluhan ekstremitas atas 5-6 sebanyak 19 orang (70,4%). Mensupport kebutuhan pekerja dalam melakukan kegiatan kerja yang baik danpencegahan terhadap keluhan ekstremitas atas agar memiliki aturan baku sehingga pekerja terlindungi dari keluhan akibat pekerjaannya.
Kualitas Air Bersih Serta Hubungannya dengan Insidensi Diare pada Balita di Wilayah Pesisir
Authors: Khairunnisa Maulida , Joko Tri , Raharjo Mursid
Published: September 2023

Di negara berkembang seperti Indonesia, diare masih menjadi 10 penyakit terbesar penyebab kematian utama dan malnutrisi pada anak dibawah lima tahun (balita). Kondisi kualitas air bersih di wilayah permukiman pesisir yang berada di bawah permukiman laut memungkinkan terjadinya pencemaran air tanah menjadi lebih asin atau disebut air payau akibat intrusi air laut yang didorong oleh penurunan muka tanah (land subsidence) akibat abtraksi air tanah yang melebihi kapasitas serta peningkatan beban bangunan. Tujuan literatur review ini untuk mengetahui kandungan salinitas, total dissolve solid (TDS), dan Eschericia coli (E.coli) serta hubungan dengan insidensi diare pada balita. Penelitian ini menggunakan metode systematic review. Hasil studi literatur menunjukkan bahawa kandungan salinitas, TDS, dan E.coli pada air bersih berhubungan dengan kejadian diare dan e.coli mampu bertahan pada air asin tanpa menghilangkan sifat patogennya dalam menyebabkan diare, serta adanya intrusi air laut mampu meningkatakan kandungan salinitas pada air tanah.
Pengaruh Pendidikan Kesehatan Berbasis Media Sosial Instagram (Social Media Campaign) Terhadap Peningkatan Pengetahuan Remaja Tentang Dismenore di SMA Negeri X
Authors: Aulia Lulyana , Pinem Lina Herida
Published: September 2023

Latar Belakang: Dismenore adalah nyeri haid yang disebabkan oleh pelepasan prostaglandin yang berlebihan. Ini meningkatkan kontraksi rahim, yang menyebabkan rasa sakit saat menstruasi. Apabila dismenore tidak ditangani, dapat mengakibatkan terganggunya seorang perempuan yang sedang mengalaminya. Oleh karena itu, perlu dilakukan pendidikan kesehatan tentang dismenore. Dengan menggunakan media sosial seperti Instagram, semua orang dapat mengakses materi dari pendidikan kesehatan tentang dismenore. Tujuan: Tujuan dari penelitian ini adalah untuk mengetahui pengaruh penggunaan media sosial Instagram menjadi media edukasi terhadap peningkatan pengetahuan tentang dismenore. Metode: Penelitian ini merupakan penelitian menggunakan kuantitatif pendekatan studi intervensi/studi eksperimen, dengan metode pre eksperimental dan perencanaan yang digunakan adalah one group pretest dan posttest design dengan jumlah sampel 68 responden. Pengumpulan data dilakukan dengan penyebaran lembar kuesioner. Hasil: Penelitian ini menggunakan uji non parametrik yaitu uji Wilcoxon didapatkan hasil signifikan p<0.001. Simpulan: Berarti terdapat pengaruh pendidikan kesehatan berbasis media sosial Instagram (Social Media Campaign) tentang dismenore terhadap tingkat pengetahuan remaja putri di SMA Negeri X.
CO2 concentration and UV-B radiation changes the photosynthetic pigments and biochemical concentrations in UAE native plants grown in open top chambers
Authors: Karthishwaran Kandhan , Alzayadneh Wasef , Alyafei Mohammed
Published: September 2023

The interactive impacts of the elevated atmospheric carbon dioxide (CO2) concentration and ultraviolet-B (UV-B) radiation on the morpho-physiological traits of UAE native plants are not clearly understood. Elevations of increased atmospheric carbon dioxide (CO2) concentration and ultraviolet-B (UV-B) irradiation in the growth environment may have a high impact on the accumulation of carbon in plants, and the different factors may work in opposite directions or induce additive effects. In this study, the mitigating effects of three native plants (Aerva javanica, Capparis spinosa, and Lycium shawii) on environmental stress were evaluated in open top chambers (OTC) under transparent conditions in the hot climate of the United Arab Emirates. The physiological attributes such as photosynthesis, tissue content of chlorophyll and carotenoids with simultaneous determination of biochemical constituents were assessed to understand the plant response mechanisms to the interaction of CO2 and UV-B. Under prevalent experimental conditions, UV-B radiation did not affect the measured physiological parameters. Results revealed that traits and varieties tolerant to a combination of stress situation provide novel insight into the mechanisms of tolerance and adaptations and will be useful to devise strategies for development of improved native plants suitable for this region through breeding programs and genetic engineering.
THE EFFECT OF POLITICAL CONNECTIONS, FINANCIAL STABILITY, SUPERVISORY EFFECTIVENESS AND AUDITOR TURNOVER ON TAX AGGRESSIVENESS
Authors: Nugrahanti Yeterina
Published: September 2023

Abstract
This research is aimed to provide empirical evidence about relationship between political connection, financial stability, effective monitoring and change in auditor on tax aggressiveness. Using purposive sampling, this research selects manufacturing companies that are listed in Indonesian Stock Exchange (IDX) in the period 2018-2020 as samples. Selected company data amounted to 86, so the total observation in this research are 258 firm-years. The data examination in this research uses multiple regression with dated panel. The results of this research indicate that political connection and effective monitoring have a significant negative effect on tax aggressiveness. Meanwhile, financial stability have a significant positive effect on tax aggressiveness. Change in auditor has no significant effect on tax aggressiveness. These results mean that change in auditor conducted by the company can not detect tax aggressiveness.
 Abstrak
Penelitian ini bertujuan untuk memberikan bukti empiris terkait hubungan antara koneksi politik, stabilitas keuangan, efektivitas pengawasan, dan pergantian auditor terhadap agresivitas pajak. Dengan menggunakan metode purposive sampling, penelitian ini memilih perusahaan manufaktur yang terdaftar di Bursa Efek Indonesia (BEI) pada periode 2018-2020 sebagai sampel. Data perusahaan terpilih berjumlah 82, sehingga total pengamatan dalam penelitian ini adalah 258 perusahaan. Metode pengujian dalam penelitian ini menggunakan analisis regresi berganda dengan data panel. Hasil penelitian ini menunjukkan bahwa koneksi politik dan efektivitas pengawasan memiliki dampak negatif yang signifikan terhadap agresivitas pajak. Sementara itu, stabilitas keuangan memiliki dampak positif signifikan terhadap agresivitas pajak. Pergantian auditor tidak berpengaruh signifikan terhadap agresivitas pajak. Hasil ini menunjukkan bahwa pergantian auditor yang dilakukan perusahaan tidak dapat mendeteksi agresivitas pajak yang dilakukan oleh perusahaan.
PERFIL CLÍNICO E EPIDEMIOLÓGICO DE MULHERES QUE RECEBERAM DIAGNÓSTICO DE SÍNDROME HIPERTENSIVA NA GESTAÇÃO
Authors: Dorner Andressa , Ribeiro Camila Cristiane Formaggi Sales , Moraes Aluana , Schimiguel Aline Domingues
Published: September 2023

Introdução: caracteriza-se hipertensão gestacional por pressão arterial igual ou superior a 140 x 90 mmHg aferida em condições ideais em pelo menos três ocasiões, diagnosticada pela primeira vez na gestação, a partir de 20ª semana de IG (Idade Gestacional). Objetivo: analisar o perfil clínico e epidemiológico de mulheres que receberam diagnóstico de síndrome hipertensiva na gestação. Metodologia: pesquisa descritiva e exploratória, realizada em um Centro de Saúde/Unidade Básica de Saúde de um município de pequeno porte localizado no Oeste do Paraná. O instrumento de coleta de dados foi um roteiro para entrevista individual contendo questões abertas e estruturadas, que foi respondido via formulário online do Google Forms®. Os dados de caracterização das participantes foram analisados descritivamente. O projeto de pesquisa foi aprovado pelo Comitê de Ética em Pesquisa. Resultados: dentre as entrevistadas, 37,5% apresentaram a hipertensão até as 20 semanas de gestação, e 62,5%apresentaram após a 20° semana da gestação. A idade de 62,5% das mulheres era entre 15 a 30 anos e 75% se autodeclararam brancas. Todas as participantes relataram realizar alguma atividade física e 71,4% seguiu alguma restrição alimentar. Uma entrevista apresentou a afecção associada de diabetes e duas delas evoluíram para complicações, sendo elas parto prematuro e síndrome de HELLP. Conclusão: após análise clínica e epidemiológica da hipertensão arterial na gestação, percebe-se que a idade predominante não é elevada, apenas uma teve comorbidade associada, e duas obtiveram desfechos desfavoráveis, concluindo-se que o perfil da maioria mostra um acompanhamento pré-natal de qualidade.
Desafios relacionados à saúde mental dos médicos
Authors: Almeida Alberto Carvalho de , Farias Ana Lúcia Crispim de
Published: September 2023

O dia 01 de maio é reconhecido internacionalmente como o Dia do Trabalho. Comemorado desde o final do século XIX, a data busca chamar atenção para as condições de trabalho de pessoas de todo o mundo. Estudos revelam que os médicos são uma das profissões que mais têm a saúde mental prejudicada. Por que isso acontece? Como os profissionais podem se proteger das doenças mentais?
Semiotic Analysis of Patriotism in Hacksaw Ridge and Letters from Iwo Jima Movie
Authors: Syaeful Rahman Mohamad Gibran
Published: September 2023

Each country have different meaning of Patriotism. Therefore, this research comparing on the movie of Hacksaw Ridge and Letters from Iwo Jima since both of the movies showed differences perspective of patriotism since both of them from different culture. The research aimed at revealing the semiotic of patriotism in Hacksaw Ridge  and Letters from Iwo Jima movie. This research is based on Roland Barthes semiotic theory, Nathanson patriotism theory and Joana Japanese patriotism. The qualitative method was employed by analyzing the symbols that indicate the act of patriotism found in the movie. The research used a descriptive design. The object of the research is the character and the background of the set was taken. Document analysis was used as the instrument in order to get the valid data. There are 57 data that took from the 10 scenes from each movies to symbolize the Dennotative, Connotative and Myth. From the analysis, three types of symbols were found that showed by the character or the background set. They were data 33,33% of Dennotative (10 occurrences), 33,33% of Connotative(10 occurrences) and 33,33% of Myth(10 occurrences) in Hacksaw Ridge movie. As for the Letters From Iwo Jima, 37% of Dennotative (10 occurrences), 37% of Connotative (10 occurrences) and 26% of Myth (7 occurrrences). The data semiotic Analysis were based on Roland Barthes theory
Modal Auxiliaries as Epistemic Devices in Marking Scientific Researchers’ Uncertainty on Covid-19
Authors: Zulkarnain Nur Azwin , Wahid Ridwan , Jan Jariah Mohd
Published: September 2023

The early phase of the COVID-19 pandemic caused a lot of pressure to scientists due to the novel nature of the coronavirus. As experts in the field, they were expected to produce only reliable information. Owing to the limited data available at the time, there were many uncertainties surrounding the virus. However, studies that looked into how the uncertainties were navigated are scarce. This corpus-based study investigates this issue using the system value of modal operators by Halliday and Matthiessen (2014), along with Dong et al.’s (2020) classification of COVID-19 research themes to explore levels of scientific researchers’ certainty in presenting information about coronavirus. Specifically, their choices of modal auxiliaries as epistemic devices are analysed. Results demonstrate that researchers mainly conduct studies on epidemiology with the lowest degree of certainty by utilising modals such as may, could and might. Furthermore, while some of the propositions expressed do display researchers’ assumptions of possibilities, they however, are presented with insufficient evidence. These findings help to untangle scientific researchers’ expressions of uncertainty and certainty through their use of epistemic devices and contribute to a better understanding of their intentions in conveying vital information.
The Effect of Guessing Picture Application on the Students’ Vocabulary Mastery of 7th Graders at SMPN 1 Plosoklaten
Authors: Fatkurohmah Umi , Fitriyah Ima , Donasari Renita
Published: September 2023

Vocabulary is important in English because it is the main capital for learning various skills in a language. Therefore, teaching techniques are needed to teach vocabulary appropriately. Teaching vocabulary can be done easily through descriptive text because students will produce a lot of vocabulary to describe something. Moreover, interesting and creative teaching media uses technology will help the teaching of descriptive text, namely Guessing Picture Application. The purpose of this study is to find out the effect of Guessing Picture Application in the students' vocabulary mastery of 7th graders at SMPN 1 Plosoklaten. This research used quantitative approach of research method by using quasi-experimental design, Guessing Picture Application to teach vocabulary in experimental class and Guessing Game to teach vocabulary in control class. The data collection used three steps, namely pre-test, treatments, post-test. Then, the researcher found the result of students’ achievement after they were taught by Guessing Picture Application or Guessing Game (Guessing Picture without Application). This research used ANCOVA in SPSS to analyze the data. The results of this study showed that the significance was 0.014. It was less than 0.05 (0.014 < 0.05). It means this study found a significant difference between students who were taught using Guessing Picture Application and students who were taught by Guessing Game. Therefore, it could be concluded that Guessing Picture Application effectively used in teaching vocabulary since the student could memorize vocabulary better than by using Guessing Game, especially in teaching descriptive text for the seventh-grade students of SMPN 1 Plosoklaten.
The Differences of Language Use between Males and Females in Sundanese Language in Informal Conversation
Authors: Fitriani Rani Ligar , Sundari Sinta Siti , Romdoni Nijar Kurnia
Published: September 2023

ABSTRACTOral language has an important role in human life. Oral language is used in both formal and informal communications. In fact, in everyday life humans use oral language more than writing. Oral language can take the form of lectures, stories, discussions, teaching, sermons, oral reports, conversations, and speeches. The most common oral language activity is conversation. Conversations are influenced by various factors, including: gender, age, occupation, location, content, situation, and purpose. Men and women as part of society, are used to having conversations, both with family, teachers, neighbors and friends. In reality, the languages spoken by men and women are very different. This can be seen from the way they speak. This study aims to find out how the differences in the languages used by men and women in informal Sundanese conversations on campus and find out the factors that influence the appearance of differences in the languages used by men and women in informal Sundanese conversation on campus. This research is a qualitative research. In this study, researchers took a sample of 4 students from Siliwangi University, Faculty of Teacher Training and Education who were selected using a purposive sampling technique. Based on observations and interviews, the results obtained are that in general, the differences in the language used by men and women in informal Sundanese conversations on campus are that men use more harsh and impolite words when speaking, while women are more polite and more use soft words when speaking. While the factors that influence the emergence of differences in the languages used by men and women in informal Sundanese conversations on campus include association, environment, native culture, habits, family and friends.
Dust in the wind & the snowy Alps: a cautionary tale
Authors: Francis Diana
Published: September 2023

Clouds are an indispensable part of our Earth’s atmosphere. Although closely associated with rain, water is not the only substance a cloud can carry. Using satellite images, we examined how vast plumes of atmospheric dust from the Sahara Desert found their way towards the northern Europe and investigated their impact on the snowy Alps.
Age-induced unsealing of the "Pandora's box": resurrection of endogenous retroviruses
Authors: Liu Xiaoqian , Ren Jie , Liu Guang-Hui
Published: September 2023

Aging is like a box full of secrets. Inside this "Pandora's box" lies a ticking time bomb of viruses, obsolete from millions of years ago, called endogenous retroviruses (ERVs). Using different aging models and technologies, researchers have proven that the reactivation of ERVs acts as both a biomarker and driver of aging, which provides potential interventions to “control the plague” of aging.
Usefulness of truenat-derived DNA from extrapulmonary specimens in direct detection of drug resistant tuberculosis by line probe assay
Authors: Agrawal Sarika Jain , V Mamatha , N Somashekar
Published: September 2023

Objectives:

Isoniazid (INH) and second-line drug resistance (DR) detection through line probe assay (LPA) takes long in extrapulmonary (EP) specimens because culture growth needs to be obtained to perform deoxyribonucleic acid (DNA) extraction due to the paucibacillary nature of these specimens. Knowing the DR pattern at the earliest is key to success of the treatment. Delay in appropriate tuberculosis (TB) treatment in EP TB patients runs the risk of DR amplification, significant disease damage, and patient loss to follow-up. Here, LPA was attempted on truenat-derived DNA elute from EP specimens, which, in routine, is discarded after the truenat test, to determine drug sensitivity test (DST) for INH and, where necessary, for second-line drugs (Fluoroquinolones, Kanamycin, amikacin, and capreomycin).

Material and Methods:

Truenat, acid-fast bacilli culture, and fluorescent microscopy were performed on all EP samples that were received at the laboratory during June–September 2022. DNA elute that was left over from 59 truenat Mycobacterium tuberculosis (MTB) positive EP samples were subjected to Genotype MTBDR plus Ver 2.0 assay.

Results:

MTBDR plus assay (DNA elute) detected MTB and rifampicin (RIF) and INH DST in 47 samples (79.6%) having truenat MTB count of 7.8 × 102 colony-forming unit/milliliter and above. It also detected RIF DST in 65.2% truenat RIF indeterminate samples and DST for both RIF and INH in 60% of culture negative EP specimens. DST results by LPA (DNA elute) completely concorded with standard indirect LPA (on 21 culture isolates from smear-negative specimens). The MTBDRsl yield was however relatively low (11.1%), although second line LPA (SLLPA) was performed only on 9 first-line DR samples.

Conclusions:

Left-over truenat-derived DNA elute is a significant sample by-product that can significantly speed up and increase the yield of determination of MTB DST in EP samples for RIF and INH, the most critical drugs for TB treatment.
MAGNETIC WATER EFFECTS ON GROWTH AND SOME PHYSIOLOGICAL CHARACTERISTICS OF PAULOWNIA TOMENTOSA THUNB UNDER CADMIUM STRESS CONDITIONS
Authors: Abdullah Ara F. , Albarznjii Ikbal M.
Published: September 2023

Paulownia (Paulownia tomentosa) is considered as one of the world's fastest-growing species of trees and most widely used for commercial. This research was done as a factorial experiment in Koya city, Erbil, Iraq during 2021-2022 to study the effects of magnetic water (MW) at (0, 500,1000, 1500 and 2000) gauss and cadmium chloride (Cd) at (0, 3.33, 6.66 and 10 mg Kg-1soil) on some growth, physiological and biochemical properties of this plant. Results demonstrate that MW had non-significant differ regarding the survived and the velocity of cutting outgrowth compare to using tap water, whereas Cd application increased the velocity of cutting outgrowth. At least one of MW powers increased significantly each of plant leaf-area, stem diameter, shoot and root fresh weight and dry matter content, as well as all Cd concentrations increased the plants leaves number, leaf-area, stem diameter. Cd had more effects on roots than plant shoots, where it has non-significant effects on shoot high or dry matter, whereas it increased each of shoot and root fresh weight significantly compared to the control treatment. Low power MW (500 and 1000) gauss performed better than high powers (1500 and 2000) gauss in increasing the content of photosynthesis pigments. Utilizing magnetic water greatly enhanced total carotenoids and chlorophyll a, b, regardless to device power. Chlorophyll (a and b) were both significantly reduced by high Cd concentrations; however it was significantly increased at low concentrations as compared to other treatments. High power MW decreased significantly peroxidase enzyme activity and proline content whereas it decreased the percent of total carbohydrate compared to other treatments. Cd application decreased each of peroxidase enzyme activity, percent of total carbohydrate content, increased ascorbic acid and proline significantly in comparing to the control.
Demographics and Outcome of Ankle Arthroplasty Supplementary Report
Authors:   Australian Orthopaedic Association National Joint Replacement Registry, Smith Paul N. ,   Australian National University Medical School, Lewis Peter L. ,   Australian Orthopaedic Association National Joint Replacement Registry,   University of Adelaide Medical School, Gill David RJ ,   Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR), McAuliffe Michael J ,   Australian Orthopaedic Association National Joint Replacement Registry,   Queensland University of Technology, McDougall Catherine ,   Australian Orthopaedic Association National Joint Replacement Registry,   University of Queensland Medical School, Stoney James D ,   Australian Orthopaedic Association National Joint Replacement Registry, Vertullo Christopher J. ,   Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR),   Griffith Centre of Biomedical and Rehabilitation Engineering , Griffith University,   Knee Research Australia, Wall Christopher J. ,   Australian Orthopaedic Association National Joint Replacement Registry,   University of Queensland Rural Clinical School, Corfield Sophia ,   Australian Orthopaedic Association National Joint Replacement Registry, Cashman Kara ,   South Australian Health and Medical Research Institute, Cuthbert Alana R ,   South Australian Health and Medical Research Institute, Du Peiyao ,   South Australian Health and Medical Research Institute, Harries Dylan ,   South Australian Health and Medical Research Institute, Holder Carl ,   South Australian Health and Medical Research Institute, Lorimer Michelle F ,   South Australian Health and Medical Research Institute, Stavrou Peter ,   Australian Orthopaedic Association National Joint Replacement Registry
Published: September 2023

This Ankle Arthroplasty Supplementary Report is based on the analysis of 4,646 ankle procedures with a procedure date from 2006 up to and including 31 December 2022. This Report is one of 16 supplementary reports to complete the AOANJRR Annual Report for 2023. Information on the background, purpose, aims, benefits and governance of the Registry can be found in the Introductory chapter of the 2023 Hip, Knee and Shoulder Arthroplasty Annual Report. The Registry data quality processes including data collection, validation and outcomes assessment, are provided in detail in the Data Quality section of the introductory chapter of the 2023 Hip, Knee and Shoulder Arthroplasty Annual Report: https://aoanjrr.sahmri.com/annual-reports-2023.
Development of rules for budget allocation and methods for evaluating media plans for the digital space
Authors: Khokhlov D. A.
Published: September 2023

The article studies methods of advertising campaign budget allocation in digital space using advertising hypotheses. The author proposes a new approach based on the use of advertising hypotheses as an advertising medium. A form of media plan specifically designed for digital space has been presented. Special attention is paid to two types of advertising campaigns: those that pay for clicks or impressions and those that use direct marketing tools (SMS, mobile notifications and email newsletters). A way to evaluate media plan effectiveness has been suggested. The author believes that the main task at the stage of media planning is to determine whether the developed advertising hypothesis is able to achieve the planned indicators. This approach can improve advertising campaigns effectiveness in digital space and ensure more accurate budget allocation. The results of the study can be useful for marketers and advertising agencies, helping them make informed decisions when planning and optimizing advertising campaigns in digital space.
Factors of heterogeneity of mortgage refinancing in the Russian regions
Authors: Gafarova E. A.
Published: September 2023

During the period of soft monetary policy in Russia, there was heterogeneous regional growth of mortgage refinancing. Social, demographic, economic and financial indicators of the Russian regions explain interregional differences in mortgage refinancing. The article confirms the hypothesis about heterogeneity of effect of reducing average mortgage rate on mortgage refinancing in the Russian regions. Empirical estimates have been obtained by panel vector autoregression for groups of regions depending on the average income of population and average housing prices. The greatest increase of mortgage refinancing reduction of mortgage rates occurred in groups of regions with highand middle-income levels and liquid housing market. When mortgage-lending conditions are relaxed, regions with low average per capita incomes benefit least from mortgage refinancing.
Adaptation of elderly people and various inequalities in the post-pandemic time
Authors: Galkin K. A.
Published: September 2023

The article studies situational inequalities emerged during the pandemic and peculiarities of adaptation of elderly people in the post-pandemic time. The research focuses on everyday projections of inequalities of elderly people living separately in the federal city and rural areas. To examine inequalities, the paper uses microsociological optics. It made it possible to analyze how structural inequalities affect the lives of the elderly and what are the ways to adapt after the pandemic that triggered the processes of protection and self-preservation. The empirical base of the study is 30 semi-structured interviews collected in 2022 in St. Petersburg and villages of the Republic of Karelia. The article describes such situational inequalities as digital inequalities, inequalities in accessing and receiving information, spatial inequalities, and inequalities in receiving medical care as main inequalities. The study concludes that emotional reflection, availabilities of hobbies or emergence of new ones, revision of previous resources, types of communication and ways of solving problems, shift of focus from caring for family and relatives to caring for themselves create positive opportunities for adaptation for older people.
Understanding the Mechanical Properties of Ultra-Deformable Liposomes Using Molecular Dynamics Simulations
Authors: Xu Jiaming , Karra Vyshnavi , Large Danielle , Auguste Debra , Hung Francisco
Published: September 2023

Improving drug delivery efficiency to solid tumor sites is a central challenge in anti-cancer therapeutic research. Our previous experimental study (Guo et al., Nat. Commun. 2018, 9, 130) showed that soft, elastic liposomes had increased uptake and accumulation in cancer cells and tumors in vitro and in vivo respectively, relative to rigid particles. As a first step towards understanding how liposomes’ molecular structure and composition modulates their elasticity, we performed all-atom and coarse-grained classical molecular dynamics (MD) simulations of lipid bilayers formed by mixing a long-tailed, unsaturated phospholipid with a short-tailed saturated lipid with the same head group. The former type of phospholipids considered were 1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) and 1,2-dipalmitoleoyl-sn-glycero-3-phosphocholine (termed here DPMPC). The shorter saturated lipids examined were 1,2-diheptanoyl-sn-glycero-3-phosphocholine (DHPC), 1,2-didecanoyl-sn-glycero-3-phosphocholine (DDPC), 1,2-dilauroyl-sn-glycero-3-phosphocholine (DLPC), and 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC). Several lipid concentrations and surface tensions were considered. Our results show that DOPC or DPMPC systems having 25-35 mol% of the shortest lipids DHPC or DDPC are the least rigid, having area compressibility moduli KA that are ~10% smaller than the values observed in pure DOPC or DPMPC bilayers. These results agree with experimental measurements of the stretching modulus and lysis tension in liposomes with the same compositions. These systems also have lower areas per lipid, form more uneven x-y interfaces with water, the tails of both primary and secondary lipids are more disordered, and the terminal methyl groups in the tails of the long lipids DOPC or DPMPC wriggle more in the vertical direction, compared to pure DOPC or DPMPC bilayers or their mixtures with the longer saturated lipids DLPC or DMPC. These observations confirm our hypothesis that adding increasing concentrations of the short unsaturated lipids DHPC or DDPC to DOPC or DPMPC bilayers, alters lipid packing and thus make the resulting liposomes more elastic and less rigid. No formation of lipid nanodomains was noted in our simulations, and no clear trends were observed in the lateral diffusivities of the lipids as concentration, type of secondary lipid and surface tension were varied.
Implications of Ga Promotion and Metal-Oxide Interfaces in Tailored Propane Dehydrogenation Catalysts Supported on Carbon
Authors: Brack Enzo , Plodinec Milivoj , Willinger Marc-Georg , Copéret Christophe
Published: September 2023

Propane Dehydrogenation is a key technology, where Pt-based catalysts have widely been investigated in industry and academia, with development exploring the use of promoters (Sn, Zn, Ga, etc.) and additives (Na, K, Ca, Si, etc.) towards improved catalytic performances. Recent studies have focused on the role of Ga promotion: while computations suggest that Ga plays a key role in enhancing catalytic selectivity and stability of PtGa catalysts through Pt-site isolation as well as morphological changes, experimental evidence are lacking because of the use of oxide supports that prevent more detailed investigation. Here, we develop a methodology to generate Pt and PtGa nanoparticles with tailored interfaces on carbon supports by combining surface organometallic chemistry (SOMC) and specific thermolytic molecular precursors containing or not siloxide ligands. This approach enables the preparation of supported nanoparticles, exhibiting or not an oxide interface, suitable for state-of-the art electron microscopy and XANES characterization. We show that the introduction of Ga enables the formation of homogenously alloyed, amorphous PtGa nanoparticles, in sharp contrast to highly crystalline monometallic Pt nanoparticles. Furthermore, the presence of an oxide interface is shown to stabilize the formation of small particles, at the expense of propene selectivity loss (formation of cracking side-products, methane/ethene), explaining the use of additives such as Na, K and Ca in industrial catalysts.
A Membrane-Electrolyte System Approach to Understanding Ionic Conductivity and Crossover in Alkaline Flow Cells
Authors: George Thomas , Thomas Isabelle , Haya Naphtal , Deneen John , Wang Cliffton , Aziz Michael
Published: September 2023

Membrane transport properties are crucial for electrochemical devices, and these properties are influenced by the composition and concentration of the electrolyte in contact with the membrane. We apply this general membrane-electrolyte system approach to alkaline flow batteries, studying conductivity and ferricyanide crossover of Nafion and E-620. We report undetectable crossover for as-received Nafion and E-620 after both sodium and potassium exchange, but high ferricyanide permeability of 10^−7 to 10^−8 cm^2 s^−1 for Nafion subjected to pre-treatment prevalent in the flow battery literature. We show how the electrolyte mass fraction in hydrated membranes regulates the influence of ion concentration on membrane conductivity, identifying that increasing electrolyte concentration may not increase membrane conductivity even when it increases electrolyte conductivity. To illustrate this behavior we introduce a new metric, the membrane penalty, as the ratio of the conductivity of the electrolyte to that of the membrane equilibrated with the electrolyte. We discuss the tradeoff between flow battery volumetric capacity and areal power density that arises from these findings. Finally, we apply insights from this approach to provide recommendations for use of membranes in alkaline flow cells, and electrochemical reactors in general.
Prospective Validation of HydraScreen: Virtual Screening and Hit Identification in IRAK1
Authors: Kamuntavičius Gintautas , Prat Alvaro , Paquet Tanya , Bastas Orestis , Abdel Aty Hisham , Sun Quing , Rines Dan , Siladi Marc , Tal Roy , Norvaisas Povilas
Published: September 2023

In this proof-of-concept study, we combine Ro5's digital drug discovery platforms SpectraView and HydraScreen with Strateos' robotic cloud labs capabilities to augment and accelerate target and hit identification. Using SpectraView to select IRAK1 as the target, we prospectively validate HydraScreen, a structure-based deep learning model. We demonstrate that HydraScreen could identify up to 23.8% of all hit compounds by screening only 1% of the compound library, simultaneously identifying the three of the most potent (nanomolar) scaffolds present in the library. All three nanomolar scaffolds identified in our project are novel for IRAK1 and lend themselves for future development. HydraScreen outperforms traditional methods in an unbiased prospective evaluation and offers advanced features such as ligand pose confidence scoring. Thus, SpectraView and HydraScreen are innovative tools which can aid and expedite the stages of early drug discovery.
Antibacterial marinopyrroles and pseudilins act as protonophores
Authors: Castro-Falcon Gabriel , Straetener Jan , Bornikoel Jan , Reimer Daniela , Purdy Trevor , Schempp Florence , Liu Dennis , Linington Roger , Brötz-Oesterhelt Heike , Hughes Chambers
Published: September 2023

Elucidating the mechanism of action (MoA) of antibacterial natural products is crucial to evaluating their potential as novel antibiotics. The marinopyrroles, pentachloropseudilin, and pentabromopseudilin are densely halogenated, hybrid pyrrole-phenol natural products with potent activity against Gram-positive bacterial pathogens like Staphylococcus aureus. However, the exact way in which they exert this antibacterial activity has not been established. In this study, we explore their structure-activity relationship, determine their spatial location in bacterial cells, and investigate their MoA. We show that the natural products share a common MoA based on membrane depolarization and dissipation of the proton motive force (PMF) that is essential for cell viability. The compounds show potent protonophore activity, but do not appear to destroy the integrity of the cytoplasmic membrane via the formation of larger pores or interfere with the stability of the peptidoglycan sacculus. Thus, our current model for the antibacterial MoA of marinopyrrole, pentachloropseudilin, and pentabromopseudilin stipulates that the acidic compounds insert into the membrane and transport protons inside the cell. This MoA may explain many of the deleterious biological effects in mammalian cells, plants, phytoplankton, viruses, and protozoans that have been reported for these compounds.
EL MARXISMO Y LA LIBERACIÓN HOMOSEXUAL. LAS RELACIONES DE MAGNUS HIRSCHFELD CON EL PARTIDO SOCIALDEMÓCRATA DE ALEMANIA Y CON EL PRIMER GOBIERNO SOVIÉTICO
Authors: Gaido Daniel
Published: September 2023

La anulación y reimposición del “delito de sodomía” y la creación del primer movimiento de liberación homosexual. La colaboración de Magnus Hirschfeld con el Partido Socialdemócrata de Alemania para la despenalización de la homosexualidad. Liberación homosexual y liberación de las mujeres en el Partido Socialdemócrata y en el Partido Comunista de Alemania. La despenalización de la homosexualidad en la Rusia soviética y las leyes contra la prostitución de menores en Transcaucasia y en Asia Central. La persecución de Magnus Hirschfeld por los Nazis y la recriminalización de la homosexualidad en la Unión Soviética por Stalin.
Review of the Effect of Problem-Solving Training Group on the Social Problem-Solving Skills of Female Convicts
Authors: ÜNLÜ SAĞDIÇ Eda , ÇOLAKKADIOĞLU Oğuzhan , DEMİR Sezai
Published: September 2023

This study aims to examine the effectiveness of the psycho-education group-based program aimed at improving the social problem-solving skills of female prisoners. The applied program is adopted by Çekici & Güçray (2012) based on the five-stage approach model in social problem-solving (D'zurilla & Nezu, 2007; Nezu et al., 2007). The research is in the semi-experimental design, and one of the types of the experimental design, "real experimental model with pretest-posttest control group" was used. The implementation was carried out with 36 convicts in Karataş Prison in Adana province in the Women's Open Penal Institution. Since the sample did not show a normal distribution, it was evaluated by the Wilcoxon Signed Rows Test, one of the non-parametric analysis methods used to compare the difference between the scores of the two sets of measurements. As a result of the analysis, it was found that the use of a positive orientation-rational problem-solving style to the problem, which is a positive coping style, increased social problem-solving skills in female convicts who participated in social problem-solving group practices, and their use of inattentive and avoidant styles, which are negative orientation to the problem and negative coping styles, decreased. This did not change in the results of the monitoring measurement in which the persistence of the effect was evaluated. The findings were interpreted in light of the literature data.
Can I become a social media specialist? A descriptive content analysis on the skills and qualifications necessary in job postings in Türkiye
Authors: CINGI Mustafa
Published: September 2023

The increase in the demand for digital skills has attracted attention in job postings published in the communication sector in recent years. The aim of this study is to reveal the frequently demanded skills and qualifications for the position of social media specialist, which is directly related to digital skills, in the context of Türkiye. For this purpose, descriptive content analysis was employed on 244 job postings published on Bigumigu.com and Mediacat.com, which publish the job postings of agencies in Türkiye. As a result of the analysis, it is possible to say that the most dominant demand of the job postings is experience in terms of years. Having agency experience, being fluent in English, being able to work in a team and having high communication skills are among the most demanded qualifications. Digital content management, digital advertising management, data analytics, design, reporting, and presentation skills are also among the most frequently requested skills. The most surprising result of the research is that agencies do not require a university education. It is important for universities to revise their curricula on the basis of these demands to respond to the needs of the sector and to train qualified graduates.
Digitalization of Workplace Harassment Against White-Collar Women: An Investigation in Professional Online Platforms
Authors: KOCABAŞOĞLU Özge Nur , BAŞ Özen , ÖĞÜN EMRE Perrin
Published: September 2023

Sexual harassment against women is one of the important social problems addressed all over the world. It is a fact that has existed for hundreds of years, although the place and types of it change. Harassment has been transferred to the digital environment, as everything has become digital with the Internet. It is claimed that women are subjected to harassment while working or looking for a job. To investigate the prevalence of workplace harassment and harassment on online platforms used for professional purposes and its psychological effects on victims, an online nonprobability sampling survey on 245 white-collar women aged 20-40 working in the private sector was conducted. The results suggest that the harassment that women are most exposed to is cyber harassment. It has been observed that 73 women out of every hundred have been subjected to harassment on professional digital platforms. In the types of harassment experienced, persistent online dating requests, receiving unwanted romantic messages, sexual jokes and insults are the most common types of harassment. It has been revealed that the psychological and physiological effects of physical abuse are also seen in victims of cyber harassment.