bluuebunny/crossref_metadata_2025 huggingface dataset:
IMPLEMENTASI TUJUAN PENDIDIKAN ISLAM DALAM UNDANG-UNDANG NOMOR 20 TAHUN 2003
Authors: Meiliasari Rosy , Agil Alfianti Uci Utari , Purwanti Febby
Published: October 2024

AbstrakIslam merupakan salah satu agama yang telah diakui di Indonesia dengan beberapa agama lainnya. Selain itu, mayoritas penduduk Indonesia memiliki identitas muslim dalam dunia pendidikan, berbagai masalah internal dan eksternal yang bersifat mendasar atau kompleks terus dihadapi. Dengan banyaknya masyarakat Islam berdampak pada munculnya lembaga pendidikan Islam dari berbagai jenjang formal maupun nonformal. Namun saat ini lembaga pendidikan Islam kurang mendapat perhatian. Hal ini dibuktikan dengan rasio jumlah siswa yang berbeda-beda di setiap lembaga pendidikan. Padahal tujuan pendidikan Islam telah tersirat dalam tujuan pendidikan nasional yang tercantum dalam sejumlah pasal dalam undang-undang sistem pendidikan nasional nomor 20 tahun 2003.
Nuevo centro de convenciones, exposiciones y espectáculos, Acapulco, Guerrero, México
Authors:   , Gayosso Ibarra Nathalie
Published: October 2024

Proyecto académico, que consiste en la creación de un centro de exposiciones, convenciones y entretenimiento en Acapulco, en el no sólo se aborda los retos de la arquitectura actual, sino que también se convierte en una herramienta importante para el desarrollo cultural y social de la región. Gracias a una investigación cuidadosa sobre el entorno y las necesidades de los usuarios, hemos diseñado un espacio que enriquece la identidad local y fomenta la interacción entre la comunidad. Con la implementación de soluciones arquitectónicas innovadoras y sostenibles, este centro se posiciona como un lugar clave para diversas actividades, impulsando el crecimiento económico y el turismo en Acapulco.
Nuevo centro de convenciones, exposiciones y espectáculos, Acapulco, Gro, Mx.
Authors:   , Molina Alonso Ana Lucia
Published: October 2024

La intervención urbano-arquitectónica que realizamos con la implementación de un Nuevo centro de exposiciones, convenciones y entretenimiento en Acapulco representa una oportunidad estratégica para potenciar el desarrollo económico, fortalecer la identidad cultural y atraer una amplia gama de eventos, consolidando así la posición de Acapulco como un destino multifacético y atractivo en el panorama internacional. La realización del diseño arquitectónico de este proyecto en Acapulco, siguiendo el Modelo General del Proceso de Diseño de la Universidad Autónoma Metropolitana Azcapotzalco, ha permitido desarrollar un proyecto integral que no solo responde a las necesidades funcionales y estéticas, sino que también se alinea con el contexto social y cultural de la región. A través de la elaboración de planos arquitectónicos detallados, planos de instalaciones eficientes, maquetas de estudio y renders visualmente atractivos, se ha logrado crear un espacio versátil y contemporáneo. La investigación exhaustiva sobre el tema, el usuario y el sitio ha sido fundamental para garantizar que el diseño se adapte a las expectativas y dinámicas locales, promoviendo así el uso del centro como un punto de encuentro para diversas actividades. Este enfoque holístico no solo potencia la experiencia del visitante, sino que también fomenta el desarrollo económico y turístico de Acapulco. En conclusión, el proyecto no solo cumple con los objetivos arquitectónicos, sino que se convierte en un catalizador para el crecimiento cultural y social de la región.
Nuevo centro de espectáculos y entretenimiento, Acapulco, Gro. Mx.
Authors:   , Rojas Jiménez Noe Eleazar
Published: October 2024

El "Nuevo Centro de Convenciones, Exposiciones y Entretenimiento en Acapulco" representa un hito arquitectónico y de sostenibilidad en la región, concebido no solo como un espacio multifuncional que alberga exposiciones, eventos, comercio y residencias, sino como un proyecto que refleja un compromiso profundo con la eficiencia energética, el confort de los usuarios y la protección del medio ambiente. Desde su fase de diseño, el proyecto ha integrado estrategias bioclimáticas, tecnologías de punta y un enfoque sostenible que responden a las necesidades climáticas de Acapulco, al mismo tiempo que optimizan los recursos disponibles. La implementación de sistemas pasivos como la ventilación natural, el control solar y el uso de materiales sostenibles no solo mejora el rendimiento energético del edificio, sino que también crea un entorno agradable para los usuarios. Asimismo, los sistemas de captación de agua y las instalaciones eficientes de climatización, hidráulica, eléctrica y domótica han sido diseñados para maximizar la eficiencia operativa y reducir el impacto ambiental a largo plazo. En conclusión, el "Nuevo Centro de Convenciones, Exposiciones y Entretenimiento en Acapulco" no solo se posiciona como un referente arquitectónico moderno y funcional en la región, sino también como un ejemplo de arquitectura sostenible y eficiente, que responde a las necesidades de la sociedad contemporánea. El proyecto no solo enriquece el tejido urbano y comercial de Acapulco, sino que también contribuye activamente a la sostenibilidad, generando un espacio innovador, adaptable y resiliente para las generaciones actuales y futuras.
The concept of personality and national identity in contemporary Kazakh prose
Authors: Samenkyzy Ulpan , Kulbarak Samen , Turysbek Rakimzhan , Ashirbekova Anar , Tuyakbayev Cabit
Published: October 2024

Colonialism has had a profoundly negative impact on national consciousness. Although the Republic of Kazakhstan has gained independence, it has not yet fully overcome the adverse effects of colonialism on its national consciousness. A portion of the Kazakh people has been Russified. Meanwhile, the younger generation, raised in their native language, either lacks a deep understanding of or is gradually forgetting the foundations of national identity that date back to ancient times. During the Soviet era, communist ideology prevented the population from truly knowing their history, traditions, and beliefs. In this context, literature plays a crucial role in reviving national memory. This article examines the concept of personality in literary works and the uniqueness of national identity based on the works of several contemporary authors. The introduction provides an overview of researchers’ conclusions related to the concept of personality. The ancient origins of national identity—sacred elements, rituals, shamanism, and the mystical connections between humans, nature, and animals—as depicted in literary works are analyzed within the dynamics of the present day, alongside the fates of the characters. The desecration of sacred elements is not merely ignorance but a sign of the erasure of national memory; rituals are not just words but embody sacred concepts accumulated from centuries of the people’s experience, which are reflected in the works. Accordingly, the research article analyzes and provides examples from several literary works. In compiling conclusions about the concept of personality, the study utilized descriptive, biographical, and socio-psychological methods to describe national identity in literary works and its ancient manifestations, as well as the depiction of sacred elements and rituals.
The influence of emotional intelligence and employee motivation on employee performance in telecommunication companies in the sultanate of Oman
Authors: BaOmar Salim Mohammed , Islam Muhammad Khairul , Jaaffar Amar Hisham
Published: October 2024

This study examines the impact of emotional intelligence (EI) and employee motivation on employee performance within the telecommunication industry in the Sultanate of Oman. The target population consisted of 4344 non-managerial employees across nine telecommunication companies, including Omantel, Ooredoo, Vodafone, Oman Broadband Company, Awasr Oman & Co, TEO, Oman Tower Company L.L.C, Helios Tower, and Connect Arabia International. Employing a deductive research approach, finally data were collected via an online survey from 354 respondents. The hypotheses were tested using multiple regression analysis. The results indicate that all dimensions of EI self-awareness, self-regulation, empathy, and social skills positively and significantly influence employee performance, with social skills having the strongest effect. Furthermore, both intrinsic motivation factors, such as work itself and career development, and extrinsic motivation factors, including wages, rewards, working environment, and co-worker relationships, significantly enhance employee performance. The interaction between EI and employee motivation was found to amplify these positive effects. Among control variables, age and education level showed significant impacts, while gender did not. These findings underscore the critical role of both emotional intelligence and motivation in driving employee performance. The study suggests that managers and policymakers should adopt integrated strategies that develop EI competencies and enhance motivational factors to optimize employee performance, thereby contributing to the success of organizations in the telecommunication sector.
The eco-city indicators from the local perspectives in the Northeast of Thailand
Authors: Chamaratana Thanapauge , Phatchaney Kritsada , Dasri Rasita , Liu Min
Published: October 2024

This research aims to delineate the ecocity indicators from the local perspectives in urban communities in the Northeast of Thailand. The research was quantitative survey research. Data was collected from a sample of 400 people who live in Khon Kaen Municipality and Udon Thani Municipality using a questionnaire. Data was analyzed by descriptive statistics and factor analysis. We found that the eco-city indicators from the perspective of people in the urban communities in the Northeast of Thailand were divided into three main criteria: a) economic perspectives; b) social perspectives; and c) environmental perspectives. When considering each aspect, it was found that the economic perspective had a total of 9 issues with an average of 3.06 out of 5.00, the social perspective had a total of 16 issues with an average of 3.76 out of 5.00, and the environmental perspective had a total of 14 issues with an average at 3.00 out of 5.00.
Chromosome numbers in Hieracium (Asteraceae) from Central and Southeastern Europe VIII
Authors: Musiał Krystyna , Grabowska-Joachimiak Aleksandra , Szeląg Zbigniew
Published: October 2024

Chromosome numbers of 16 taxa of Hieracium s.str. from Bulgaria, Poland and Romania are specified and their metaphase plates are illustrated. Chromosome numbers are published for the first time for H. cam- korijense subsp. rilae Rech. fil. & Zahn (4x), H. grabowskianum Nägeli & Peter (4x), H. haematopodum var. sudeticum Schack & Zahn (3x), H. lomniczkianum Szeląg (4x), H. pseudobifidum var. bucuranum Nyárady & Zahn (3x), H. umbellonigritum Szeląg (3x), H. wiesbaurianum subs. herculanum Zahn (3x), as well as six undescribed species belonging to the H. bifidum agg. (3x), H. caesium agg. (4x), H. umbrosum agg. (3x, 4x) and H. vulgatum agg. (3x) and a new supposed hybrid between H. bifidum s.lat. and H. murorum s.lat. (3x).
Cambrian-Ordovician trace fossils of the Basissletta region, northeast Spitsbergen, Svalbard
Authors: Uchman Alfred , Hanken Nils-Martin
Published: October 2024

Trace fossils of the Cambrian–Ordovician sedimentary succession of the Basissletta region, northeast Spitsbergen, Svalbard, belong to three ichnoassemblages. The first one, composed of Monocraterion and Diplocraterion, belongs to the Skolithos ichnofacies and characterises sandstones of the Tokammane Formation (lower Cambrian: Terreneuvian) deposited in a shallow subtidal setting. The overlying carbonates with pseudomorphs after evaporites (uppermost part of Terreneuvian and the Cambrian Series 2) display abundant Balanoglossites. These beds were deposited in an oxygenated but hypersaline environment. The younger Ordovician carbonates of the Kirtonryggen Formation and the mixed carbonate-clastic deposits of the Valhallfonna Formation display a more diverse but poorly preserved trace fossil suite (Phycodes, Curvolithus, Planolites, Palaeophycus) typical of the archetypal Cruziana ichnofacies. Some parts of the succession are not bioturbated, and these are characterised by dark coloured fine-grained sediments with primary lamination. They were mostly deposited between the normal and storm wave base or below the storm wave base in oxic to anoxic environments.
Enhancing carbon dioxide adsorption in a hybrid fixed bed via structuring and thermal management: a numerical study
Authors: Cutilloa Enrico A. , Neupauerb Krzysztof , Continilloc Gaetano , Bizond Katarzyna
Published: October 2024

Systems based on physical sorption are an attractive solution for CO2 capture from flue gases, biogas upgrading or gas storage. Besides the sorbent choice, one of the most important factors related to the design of such systems is proper heat management. Commonly used sorbents typically have low thermal conductivity. Nevertheless, catalyst particles characterized by high conductivity are inherently present in adsorptive (hybrid) reactors. Thus, appropriate structuring of hybrid beds can be used for controlling temperature profiles and improving the bed performance. In this study, the behaviour of a nonadiabatic adsorptive reactor described by a two-dimensional model was analysed for the adsorption step. The effect on the CO2 adsorption performance of different spatial distributions of functionalities in the bed was investigated. The optimality problem for nonuniform radial distribution of sorbent and catalyst in the bed was solved, indicating that such a configuration is a potentially important direction for structuring hybrid beds. Results demonstrate that the optimal configuration of radially distributed functionalities significantly increases the amount of CO2 absorbed under identical boundary and initial conditions for the bed. It appears that precise control of the heat generated and removed from the bed is achievable. Such control could be advantageous for the regeneration phase.
Enhanced MPPT Based on Zebra Optimization Algorithm for Control of a Partially Shaded Photovoltaic System
Authors: Draoui Abdelghani , Saidi Ahmed , Bouiri Abdesselam , Zemmit Abderrahim , Siqueira Antonio Marcos de Oliveira , Campos Julio César Costa
Published: October 2024

Objective: The objective of this paper is to adapt the Zebra Optimization Algorithm (ZOA) to track the Global Maximum Power Point (GMPP) of a PV system when subjected to partial shading conditions.
 
Theoretical Framework: Photovoltaic (PV) systems are increasingly being used due to their clean nature and low maintenance cost. However, solar cells exhibit a nonlinear relationship between current and voltage, which necessitates the use of Maximum Power Point Tracking (MPPT) algorithms to ensure the system operates at its full potential. Bypass diodes are integrated into PV modules to protect solar cells from damage during partial shading, but this leads to a distorted multi-peak Power-Voltage (P-V) curve. This distortion presents a challenge for algorithms to distinguish between Global Maximum Power Point (GMPP) and Local Maximum Power Points (LMPPs).
 
Method: The Zebra Optimization Algorithm (ZOA) is applied to track the GMPP of a PV system under partial shading conditions. Simulations were conducted using the MATLAB/Simulink platform to evaluate the algorithm’s performance. The focus was on ensuring fast and accurate tracking of the GMPPT under rapid changes in solar irradiance levels.
 
Results and Discussion: Simulation results demonstrated that the ZOA-based MPPT algorithm effectively tracked the GMPPT of the PV system, even under rapid variations in solar irradiance. The algorithm proved its accuracy and speed in distinguishing the GMPP from LMPPs, addressing the challenges posed by the distorted P-V curve.
 
Research Implications: The successful application of the ZOA for tracking the GMPP in partial shading conditions offers a significant improvement for PV systems. This can lead to enhanced efficiency in energy production and more reliable performance in real-world scenarios, where shading and other environmental factors frequently affect solar panels.
 
Originality/Value: This study introduces the adaptation of the Zebra Optimization Algorithm (ZOA) in MPPT for PV systems, addressing the issue of distinguishing between GMPP and LMPPs under partial shading. The approach demonstrates both innovation and practical value in improving the efficiency of PV systems in challenging environmental conditions.
Selection of Artificial Intelligence Technology For Digitalization of Order Fulfillment on Drug Factory Using Multi Criteria Decision Making
Authors: Aldayondri Irzhafarina , Dachyar M.
Published: October 2024

Objective: This paper aims to identify the most suitable Artificial Intelligence (AI) technology for the order fulfillment process in pharmaceutical factory, along with the key criteria and sub-criteria for successful AI implementation.
 
Theoretical Framework: The study integrates theories of digital transformation, process optimization, and decision-making.
 
Method: The research assesses digital readiness to evaluate a company's preparedness for digital transformation. The as-is process is mapped using BPMN to identify potential AI applications. AI technologies are then ranked using BWM and PROMETHEE methods, followed by scenario analysis to determine the optimal technology.
 
Results and Discussion: Demand Forecasting is the top AI technology for adoption in the pharmaceutical factory's order fulfillment process, reducing cycle time by 29.50% to 21.80 hours.
 
Research Implications: The research contributes to the understanding of selecting the most effective AI technology for optimizing the order fulfillment process in pharmaceutical companies, providing valuable insights for improving efficiency.
 
Originality/Value: The study proposes a perspective on applying AI to optimize the order fulfillment process in pharmaceutical factory, offering valuable insights for improving operational efficiency through digital transformation.
Humanitarian Logistics as a Guarantee of Fundamental Rights: a Theoretical and Practical Analysis in the Case of the Floods in Rio Grande do Sul
Authors: Guilherme Ana Clara Fonseca
Published: October 2024

Objective: The objective of this study is to analyze humanitarian logistics as a crucial instrument for guaranteeing these rights in disaster situations
 
Theoretical Framework: In this topic, the main concepts and theories that underpin the research are presented. The floods in Rio Grande do Sul represent a significant challenge for the protection of the fundamental rights of affected citizens. Floods are natural phenomena that, when they occur in large proportions, cause significant damage to infrastructure, the environment and people's lives. In Rio Grande do Sul, frequent flooding challenges local authorities and the community to implement effective response and recovery measures. Humanitarian logistics emerges as an essential tool in this context, acting to ensure the protection of the fundamental rights of affected populations.
 
Method: The methodology adopted for this research comprises a theoretical-practical approach, the text explores the concepts of humanitarian logistics and fundamental rights, and examines the specific case of floods in Rio Grande do Sul.
 
Results and Discussion: The results obtained revealed the results of this research showed that humanitarian logistics plays a vital role in guaranteeing fundamental rights in disaster situations, such as the floods in Rio Grande do Sul.
 
Research Implications: The practical and theoretical implications of this research are discussed, providing insights into how the results can be applied or influence practices in the field of theoretical-practical analysis of this study highlights the importance of planning, coordination, efficient distribution of supplies, and continuous monitoring to mitigate the negative impacts and protect the rights of affected populations.
 
Originality/Value: This study contributes to the literature by improving humanitarian response and ensuring that vulnerable communities receive the necessary assistance in a timely and effective manner.
Folklore motifs in the stage interpretation of Zainab Biisheva's novel "The Humiliated"
Authors: Shakurova Shaura Rashitovna , Khubbitdinova Nerkes Ahmetovna , Shagapova Gulkai Rahimyanovna
Published: October 2024

The subject of the study is the play "Humiliated" based on the novel of the same name by Z. Biisheva. Staging a literary work always requires a specific approach of the playwright and director to the artistic material. In this regard, the potential of the National Youth Theater of the Republic of Bashkortostan named after Mustaya Karim exactly meets these requirements for the production of the novel "The Humiliated" by Zainab Biisheva (director M.Kulbaev, 2019). The purpose of the study is to analyze the preservation of folklore motifs abounding in the author's work in its stage transformation. Methods used: ideological-thematic, ideological-aesthetic, comparative-historical. The work "The Humiliated" (1956-1959) by Z. Biisheva is part of a trilogy, the rest of which are called "At the Big Ica" (1965-1967) and "Emesh" (1967-1969). The play is staged according to the first part of the trilogy and captures the life story of Emesh during the Civil War with abundant depiction, artistic use of folklore material. The production director managed to reflect in two actions the main ideological and thematic, ideological and aesthetic peculiarities of the novel, to solve the main problem of the work by using the possibilities of theatrical art. The results of the conducted research can be used when writing a monograph on the history of scenic reinterpretation of the works of Bashkir writers of different years, the problem of staging an epic canvas to embody the national "epic theater" (the term Skorokhodova N.S.). The article concludes that the folklore traditions that permeate the body of the performance become that connecting thread with a bygone era, phrases in the Bashkir language used by the characters add authenticity to the theater performance.
ANALISIS PENGENDALIAN BAHAN BAKU PALLET MENGGUNAKAN METODE MATERIAL REQUIREMENT PLANNING PADA PERUSAHAAN DI CIAMIS
Authors: Permana Dodi , Aristriyana Eky , Hilman Maman
Published: October 2024

Pengendalian bahan baku merupakan proses penting dalam manajemen rantai pasokan. Ini melibatkan pengawasan dan pengelolaan semua aspek yang berkaitan dengan bahan mentah yang digunakan dalam produksi suatu produk.
Salak Bodas Pallet merupakan perusahaan yang bergerak di bidang produksi pembuatan pallet, yang dimana kayu merupakan bahan baku utama dari pembuatan pallet, jenis kayu yang di gunakan dalam produksi adalah kayu mahoni dan kayu Africa. Permasalahan yang terjadi dalam bahan baku kayu  ialah perusahaan memesan bahan baku terlalu banyak yang tidak sesuai dengan kebutuhan hal tersebut tentunya mengakibtan overstock akan bahan baku di gudang dan menuntut perusahaan harus mengeluarkan biaya lebih untuk menyimpan bahan baku tersebut digudang.
Penelitian ini dilakukan dengan cara melakukan analisis data penjualan untuk melakukan forecasting untuk mengetahui jumlah pemesanan kedepannya, selanjutnya analisis master production dari hasil forecasting dan data permintaan aktual. Kemudian validasi antara MPS dengan RCCP untuk mengetahui apakah jumlah MPS valid dengan kapasitas yang tersedia di perusahaan, dilakukan perancangan pengendalian bahan baku menggunakan Material Requirement Planning. Selanjutnya hasil dari Material Requirement Planning direkomendasikan untuk pengendalian bahan baku pada produk block board.
OPTIMALISASI PENGENDALIAN PERSEDIAAN BAHAN BAKU TEMPURUNG KELAPA DENGAN METODE ECONOMIC ORDERING QUANTITY (EOQ) UNTUK MENGHINDARI OVERSTOCK PRODUK KARBON AKTIF DI PT. AIMTOPINDO NUANSA KIMIA CABANG GARUT
Authors: Setiawan Fajar , Kurnia Yusup , Hilman Maman
Published: October 2024

PT. Aimtopindo Nuansa Kimia mengalami permasalahan dalam pengendalian persediaan bahan baku tempurung kelapa yang menyebabkan overstock produk karbon aktif. Hal ini dikarenakan perusahaan kesulitan membuat perencanaan dan pengendalian persediaan bahan baku tempurung kelapa yang disebabkan ketidakpastian pemasok dan fluktuasi permintaan konsumen. Penelitian ini bertujuan untuk mengoptimalkan pengendalian persediaan bahan baku tempurung kelapa untuk menghindari overstock produk karbon aktif. Metode penelitian yang digunakan dalam menyelesaikan studi kasus ini adalah metode EOQ. Hasil analisis penerapan metode Economic Ordering Quantity (EOQ) berdasarkan kebijakan perusahaan dapat diperoleh jumlah kuantitas pemesanannya 12 ton dengan frekuensi pemesanan 7 kali, safety stocknya 10 ton dan reorder pointnya 20 ton dan total biaya persediaan Rp. 9.585.200, dan berdasarkan permintaan konsumen dapat menurunkan jumlah kuantitas pemesanannya 8 ton dengan frekuensi pemesanan 5 kali, safety stocknya 4.4 ton dan reorder pointnya 8.8 ton dan total biaya persediaan Rp. 4.418.000
DESAIN ALAT BANTU KERJA DALAM PROSES FINISHING PRODUK SCREEN SABLON DENGAN MENGGUNAKAN METODE ANTROPOMETRI PADA UKM IDING BINGKAI DI RANCAH
Authors: Dwi Chandra Happy , Aristriyana Eky
Published: October 2024

Dalam industri bingkai screen sablon di rancah, masih terdapat keterbatasan dalam desain alat bantu kerja yang memperhatikan faktor antropometri pekerja. Banyak alat bantu kerja yang belum mempertimbangkan variasi ukuran tubuh pekerja, yang dapat mengakibatkan ketidaknyamanan, kelelahan, risiko cedera, dan penurunan efisiensi kerja. Selain itu, industri ini juga menghadapi tantangan dalam hal ergonomi, karena pekerja sering kali harus mengoperasikan mesin-mesin yang kompleks dan melakukan gerakan yang repetitif.
Metode antropometri merupakan pendekatan yang berfokus pada pengukuran ukuran, proporsi, dan dimensi tubuh manusia. Dalam konteks desain alat bantu kerja, metode antropometri dapat menjadi landasan yang kuat untuk merancang alat bantu kerja yang sesuai dengan karakteristik fisik pekerja. Dengan memperhatikan variasi ukuran tubuh antar individu, desain alat bantu kerja yang tepat dapat meningkatkan kenyamanan, mengurangi kelelahan, meminimalkan risiko cedera, dan meningkatkan efisiensi kerja secara keseluruhan. yang dilakukan dengan menggunakan alat ukur yang presisi, seperti penggaris, pengukur lingkar, dan alat pengukur elektronik. Pengukuran dilakukan pada berbagai titik tubuh, seperti tinggi badan, lebar bahu, lingkar pinggang, dan panjang lengan untuk mengetahui desain alat kerja yang ergonomis.
Hasil dari penelitian ini adalah desain baru alat kerja yang ergonomis pada mesin ampelas.
EVALUASI PEMILIHAN MATERIAL DENGAN METODE COST BENEFIT ANALYSIS DALAM PERAKITAN KOLAM BIOFLOK DI HANAN’S FISH FARM
Authors: Abdurrohman Baihaqi Salman , Kurnia Yusup
Published: October 2024

Hanan’s Fish Farm merupakan sebuah UMKM yang bergerak di bidang budidaya ikan, di mana teknologi bioflok digunakan untuk meningkatkan efisiensi dalam pengelolaan air dan lahan. Penelitian ini bertujuan untuk mengevaluasi pemilihan material yang digunakan dalam pembangunan kolam bioflok. Fokus utama penelitian ini adalah pada pemilihan material seperti terpal Polyvinyl Chloride (PVC), terpal Poliethylene (PE), dan geomembran High Density Poliethylene (HDPE), dengan mempertimbangkan berbagai faktor penting seperti biaya, ketahanan, ketersediaan, dan dampak lingkungan. Untuk memberikan rekomendasi yang paling sesuai bagi kebutuhan Hanan’s Fish Farm, penelitian ini menerapkan pendekatan Cost-Benefit Analysis (CBA) yang mencakup empat kriteria perhitungan utama: Net Present Value (NPV), Benefit Cost Ratio (BCR), Payback Period (PP) dan Life Cycle Cost (LCC). Penelitian ini merekomendasikan pemilihan material High Density Poliethylene (HDPE) yang memiliki nilai NPV tertinggi sebesar Rp.83.493.466, Benefit Cost Ratio (BCR) sebesar 32,55, dan payback period (PP) selama 2,3 bulan dan pemangkasan biaya perawatan sebesar 35 – 75,6% dari alternatif material lain.
IMPLEMENTASI METODE PERAMALAN (FORECASTING) PERMINTAAN PRODUK TAS PADA PT. FAJAR RAYA DI KECAMATAN KAWALI
Authors: Tri Purnomo Sandi , Aristriyana Eky
Published: October 2024

Perusahaan Fajar Raya yang bergerak dalam bidang produksi tas sangat perlu  untuk melakukan peramalan permintaan konsumen akan hasil produksinya. Pola pemintaan yang variatif akan mengantarkan PT Fajar Raya pada kondisi permintaan masa depan yang penuh dengan ketidakpastian. Penumpukan kelebihan stok tas di gudang PT Fajar Raya akan menimbulkan pembengkakan biaya, sehingga akan mengurangi laba perusahaan. Selain itu, ketika permintaan konsumen sedang mengalami peningkatan namun tidak ditunjang dengan kesediaan stok yang mencukupi maka perusahaan akan kehilangan kesempatan untuk mendapatkan laba. Berdasarkan permasalahan yang telah disebutkan, penulis tertarik untuk melakukan penelitian dengan judul “Implementasi Metode Peramalan (Forecasting) Permintaan Produk Tas pada P.T Fajar Raya Di Kecamatan Kawali
Non-invasive system delivering microwaves energy for localized adiposity reduction, skin laxity, and cellulite: Clinical evidence
Authors: Arrigoni Francesca , Fusco Irene , Zingoni Tiziano , Massirone Alberto
Published: October 2024

Localized adiposities are the accumulation of subcutaneous adipose tissue resulting in an alteration of the body silhouette. This study evaluates the efficacy and safety of a non-invasive microwaves (MWs) device for the treatment of localized adiposities of the thighs and abdomen. Sixteen women enrolled underwent four sessions with the study device at intervals of 30 days. Clinical evaluation, anthropometric evaluation, ultrasound evaluations, and 3D photographs were performed. Cellulite and skin laxity were evaluated. Patients filled 4-points Global Aesthetic Improvement Scale (GAIS) and 10-points Visual Analog Scale. The mean abdominal circumference significantly (P <0.05) decreased 4 weeks after the last treatment, and the mean culotte/thighs circumference significantly (P < 0.05) decreased 4 weeks after the last treatment. Both cellulite and skin laxity were improved. The GAIS scores showed satisfactory results. No adverse effects were observed. This MWs system has been found to be safe and effective in the reduction of body circumferences.
THE ROLE OF PATIENT SCREENING AND RISK STRATIFICATION IN THE PREOPERATIVE PREPARATION OF PATIENTS WITH ANTERIOR ABDOMINAL WALL HERNIAS
Authors: USHNEVYCH ZH.
Published: October 2024

Introduction. Lifestyle, poor physical condition, bad habits, malnutrition and adverse psychological factors reduce the body's resistance to overcome the physiological stress of surgery. Abdominal wall hernia repair is one of the most common surgical operations. A high body mass index, smoking, diabetes and immunosuppression are risk factors for the development of postoperative hernia, and in the case of its surgical correction, these factors significantly worsen the perioperative prognosis. Assessing the risk of serious complications and death during the perioperative period is crucial for the patient.
Aim. To assess the role and necessity of patient screening and risk stratification in the complex of preoperative preparation of patients with anterior abdominal wall hernias.
Materials and methods. In the research took part 91 patients who underwent surgical treatment of abdominal wall hernias. They were divided into 3 groups according to the type of anesthesia (general, neuraxial and fascial blocks of the abdominal wall). The analysis was carried out according to comorbidity, the presence of lifestyle risks, the risk of cardiovascular complications (LI index), the risk of anesthesia according to the ASA (American Society of Anesthesiologist's) scale and the risk of thromboembolic complications according to the Caprini scale, factors that affect the frequency postoperative nausea, vomiting and their prevention.
Results and discussions. It was determined that the most common concomitant pathology in patients of 1, 2 and 3 study groups was arterial hypertension. Ischemic heart disease was most often observed in patients of group 3. Patients with a history of acute coronary syndrome dominated in the 3rd observation group. Patients were also noted to have diabetes mellitus, chronic obstructive pulmonary disease, and a history of impaired cerebral circulation. It was determined that many patients in the studied groups did not have additional risk factors, but all of them smoked and were overweight. Many patients had anesthetic risk according to ASA II or III. Patients received combined prophylaxis of postoperative nausea and vomiting.
Conclusions. All groups were dominated by patients with an average and high risk of developing perioperative complications. Careful examination, identification of potential risk factors related to comorbidities and lifestyle are important to reduce the risk of complications in patients with abdominal wall hernias in the complex of preoperative preparation. Patients with a high risk of developing perioperative complications are recommended to choose neuraxial or regional anesthesia to prevent the development of postoperative complications.
AUDIT OF INFECTION CONTROL EFFECTIVENESS AND ANTIMICROBIAL DRUGS ADMINISTRATION IN UKRAINE: A PROSPECTIVE FOLLOW-UP
Authors: Bielka K.Y , Pechak O.V , Fomina G.A.
Published: October 2024

Indicators of antibiotic resistance in the world and in Ukraine are steadily increasing. As of 2021, there is a national standard in Ukraine that recognizes the deescalation of antibiotic therapy, but the war in Ukraine has significantly disrupted the supply of essential services. War-related infections and antimicrobial resistance are seriously affecting the health of people in Ukraine and beyond, forming a great reservoir of multidrug-resistant gram-negative infections
Aims: monitor the effectiveness of infection control and antibiotic administration in the Public Health Department of Ukraine.
Methods: Based on the Department of Surgery, Anesthesiology and Intensive Care of the PDO National Medical University named after O.O. Bogomolets, a prospective observational study was carried out - an anonymous audit of doctors, anesthesiologists and doctors of other specialties who work at the Public Health Service of Ukraine from the beginning of 2024. The investigation was carried out on the online platform Google-form. After the completion of the tracking period, all completed data was transferred to an Excel table and analyzed using additional descriptive statistics for parametric data.
Results: The results of 214 participants from different regions of Ukraine were collected. Half of the respondents reported that the department of infection control functions effectively - 105 (49.2 %), formally important - 85 (39.9 %), and does not function in 3 (1.5 %) Cefazolin as the first choice AB (57.7 %), using of Ceftriaxone (18.6 %) or Cefuroxime (7.9 %) as the 1st line of AB prophylaxis. About not using the protocol tell for us the choice of AB 2-line AB prevention and treatment of Gram+ and Gram-infection. The most common resistant pathogens in the Ukrainian health care sector were: Klebsiella pneumonia 140 (65.4 %) and Pseudomonas aeruginosa 99 (46.3 %) species. Most respondents also reported the expansion of three courses of AB therapy: 7-10 days in 97 (45.5 %) and 10 days and more – 85 (39.9 %) types.
Conclusion: most health protection regulations in Ukraine today include the creation of infection control and approval of local documents (new clinical protocols, patient routes) from infection control and administration Instruction of AB. However, wider problems are avoided without the continuation of specific protocols, the use of AB group reserve for AB prophylaxis, the choice of non-optimal empirical AB therapy, the wider acceptance of combination therapy without indications, trivial courses therapy and type of de-escalation.
Single equation approach for linear Fredholm integrodifferential equations
Authors: S. Segni , B. Tair , H. Guebbai
Published: October 2024

Our primary objective is to develop an innovative approach for the numerical so lution of the Fredholm linear integrodifferential equation. Our overarching goal is to significantly enhance computational efficiency and minimize memory space utilization which is very important in the case of large integration intervals. To begin this en deavor, we establish sufficient conditions that guarantee the existence and uniqueness of the solution. Our novel method is grounded in the single equation approach, which consists in using the variable transformation represented as v(x) = v(a) + ∫ ︁ x a v(t)dt, completed by the trapezoidal rule. This transformation plays a pivotal role in convert ing our equation into an algebraic system, thereby reducing the number of equations and unknowns in the discrete system. Underlying these developments is a fundamental requirement ensuring the existence and uniqueness of the solution. Leveraging this, we formulate theorems that establish the convergence of the approximate solution, ensuring consistency between analytical and numerical investigations. Ultimately, we conduct a comparative analysis between our newly introduced technique and the older method. This comparison serves to highlight the superior computational efficiency and reduced storage space consumption offered by our innovative digital framework.

Наша главная цель — значительно повысить вычислительную эффективность и минимизировать использование памяти, что очень важно в случае больших интервалов интегрирования. Сначала определяем достаточные условия, которые гарантируют существование и единственность решения. Наш новый метод основан на подходе с одним уравнением, он заключается в использовании преобразования переменной, представленного как v(x) = v(a) + ∫ ︁ x a v(t)dt, дополненного правилом трапеции. Оно играет ключевую роль в преобразовании нашего уравнения в алгебраическую систему, тем самым уменьшая количество уравнений и неизвестных в дискретной системе. В основе этих разработок лежит фундаментальное требование, гарантирующее существование и единственность решения. Используя это, мы формулируем теоремы, которые устанавливают сходимость приближенного решения, обеспечивая согласованность между аналитическими и численными исследованиями. В конечном итоге мы проводим сравнительный анализ между нашей новой введенной техникой и старым методом. Это сравнение служит для того, чтобы подчеркнуть существенную вычислительную эффективность и сокращенное использование памяти на диске, предлагаемые нашей инновационной цифровой структурой.
Breaking the Silence: A Comprehensive Review of Suicide
Authors:   Department of Psychiatry, ASRAM, Eluru, Andhra Pradesh, India, LH Rupa , KP Pranay ,   Department of Emergency Medicine, ASRAM, Eluru, Andhra Pradesh, India, S Shehnaz ,   Department of Genetics, Bhagwan Mahavir Medical Research Centre, AC Guards, Masab Tank, Hyderabad, Telangana, India
Published: October 2024

Suicide is a complex and multifaceted phenomenon, representing a significant global public health issue worldwide. This review explores the various aspects of suicide, including its definition, prevalence, and contributing factors. Suicide is the fourth leading cause of death among 15-29-year-olds globally, with the highest rates observed in low- and middle-income countries. Suicidal tendencies manifest in diverse forms, ranging from ideation and gestures to chronic suicidality and murder-suicide, each reflecting unique psychological, social, and biological influences. Psychological factors, particularly mental health disorders, play a significant role in suicide risk, while social isolation, economic hardship, and cultural dynamics further exacerbate vulnerability. Biological factors, such as genetic predisposition and neurobiological alterations, also contribute to suicide risk. The review highlights the importance of prevention strategies, including improving access to mental health care, crisis intervention, restricting access to means of suicide, and public awareness campaigns. The societal impact of suicide is profound affecting families, communities, and economies. Comprehensive, multi-faceted approaches are essential to reduce the global suicide rate and mitigate its impact.
Monoclonal Antibody Bioprocess Engineering Advancements Using Conversational Artificial Intelligence
Authors: Kawchak Kevin
Published: October 2024

Processing high dimensional and complex monoclonal antibody (mAb) bioprocess data in industry is now more efficient due to conversational AI. The human in the loop approach to Large Language Model (LLM) inferencing with document retrieval and chained outputs is a probable benefit to existing biotechnology workflows. Potential risks of using natural language processing are minimized due to the utility of solving problems with vast amounts of structured and unstructured mixed data that can be verified by the Human-AI team. This novel work demonstrates o1-preview, ChatGPT-4o, L3.1-405B, and 3.5 Sonnet models’ fast and stateof-the-art solutions. In specific, o1-preview provided a response to 16 papers 110x faster than the manuscript author’s time after the number of words were set equal. In addition, ChatGPT-4o was 371x faster than an optimal human researcher to examine and provide an estimate regarding dimension reduction or combinatorial optimization for a recent paper by Kao, M., et al. The third LLM speed advantage of 336x by ChatGPT-4o vs. the manuscript author was achieved using monte carlo simulations and markov chain models performance forecasts and a current paper by Konoike, F., et al. Part A featured the individual analysis of 5 recent mAb production papers, which emphasized the proficiency of o1-preview (9.9/10.0), ChatGPT-4o (9.2), and L3.1-405B (9.2) providing a forecast report. Example generations for o1-preview and L3.1-405B typically established connections between using dimension reduction or combinatorial optimization and improving bioprocesses. Part B models generated tables regarding how LLMs can improve numerical data from 5 different papers using monte carlo simulations or markov chain models. An example from ChatGPT-4o (9.0) was substantially more complete, accurate, and convincing than the table provided 3.5 Sonnet (8.0). Part C utilized the report format from Part A combined with the numerical approach from Part B across 6 additional papers, led by o1-preview (9.0) and ChatGPT-4o (8.5). The o1-preview example followed the prompt format well, citing cases of how LLMs will utilize reinforcement learning and bayesian optimization to improve mAb production. The work represents a standard for utilizing a considerable amount of bioprocess data to forecast new results, with the transition into LLMs providing near-real-time production data analysis aided by document retrieval to provide a synergistic effect with existing machine learning techniques.
Bio-based graphene-encapsulated Co@CS catalyzed selective hydrogenation of nitrile to amines via flow synthesis
Authors: Mi Siyi , liu Jianguo
Published: October 2024

Amines are basic components of bioactive compounds, natural products, drugs, and functional materials. Catalytic hydrogenation of nitrile compounds to corresponding amines is a green and efficient production method. Compared with heterogenous metal catalyzed batch reactions in high pressure of hydrogen, the flow synthesis method using heterogeneous metal catalysts can achieve higher catalyst efficiency and productivity, as well as much safer practical application. Moreover, the development of multiple utilizations of sustainable biomass materials especially in developing biobased materials for catalysts is highly demanding. So in this work, advanced flow synthesis methodology was used to prepare primary amines via bio-based chitosan Co@CS heterogeneous catalyst through the catalytic hydrogenation of nitrile. The effects of temperature, pressure, ammonia concentration, and liquid flow rate on the flow reaction were investigated. Under the optimal reaction conditions, the benzonitrile (BN) conversion rate was greater than 99%, and the selectivity of benzylamine exceeded 99%. The synthesized graphene-encapsulated Co-based catalyst with chitosan as the carrier material was tested for a long time to verify the stability of the Co@CS catalyst. The substrate expansion experiments of various aromatic nitriles gave satisfactory primary amine yields. Due to its exceptional mass and heat transport properties, the H-Flow system offers an efficient route for the large-scale synthesis of primary amines from biomass platform compounds in industrial production. This study provides new ideas and references for preparing highly selective primary amines by industrial-scale hydrogenation of nitrile compounds.
A Computational Strategy for the Theoretical Investigation of the Reactions Between Atomic Oxygen and Aromatic Compounds
Authors: Balucani Nadia , Rosi Marzio , Casavecchia Piergiorgio , Mancini Luca , Pannacci Giacomo , Vanuzzo Gianmarco
Published: October 2024

The theoretical investigation of large aromatic compounds interacting with atomic oxygen is a computationally very challenging problem for the requirements in terms of computer time and scratch disk space. The use of very accurate methods like the CCSD(T) with very extended basis sets is unfeasible. It is necessary to use less expensive methods. In this article we consider a computational strategy able to provide reasonably accurate results with affordable computing costs.
Cholesteryl-Tagged Fluorescent NAD+: A Membrane-Permeable Esterase-Sensitive Probe for ADP-ribosylation Studies
Authors: Frings Lea-Sophie , Lintfert Emma , Kohler Robin Noel , Marx Andreas , Kasprzyk Renata
Published: October 2024

ADP-ribosylation is a key protein modification involved in cell signaling pathways, where ADP-ribose units are incorporated into the macromolecules by PARP enzymes, using NAD+ as a substrate. Over years many NAD+ tools have been developed for studies on the complex role of the ADP-ribosylation, although its inability to penetrate the cell membrane poses limitations. In this work, we present a straightforward synthesis of a cell-permeable, fluorescent NAD+ analog with an esterase-sensitive linker. The NAD+ double-conjugate contained a Texas Red fluorophore and a cholesterol ligand, incorporated via a [4-(acetyloxy)phenyl]methyl N-carbamate bond. This bond improved the probe’s stability in buffer compared to our previous design and allowed for efficient cleavage by human carboxylesterase. The probe was successfully accepted as an ADP-ribosylation substrate by PARP1 and PARP10, both before and after cleavage. We demonstrated the probe’s ability to penetrate the cell membrane and used it to visualize ADP-ribosylated proteins and monitor fluorescence changes in HeLa cells under oxidative stress.
Nickel-catalysed stereoselective α-vinylation and arylation of peptide electrophiles
Authors: Hu Jie , Su Shengjie , Zhang Haodong , Gao Yan , Yang Xiaoping , Chen Yunrong , Gong Hegui
Published: October 2024

Stereoselective modification peptide α-carbons remains a challenge. In this context, transition metal-catalyzed C-C cross-coupling chemistry of peptidyl α-carbon-electrophiles has not been achieved. Herein, we report that racemic glycinyl α-C-Ts (α-TG) unit implanted in peptide backbones serves as an excellent electrophile element for vinylation/arylation with vinyl/aryl triflates/halides to afford the α-C(sp2)-modified peptides in excellent levels of diastereoselectivity, enabled by asymmetric Ni-catalyzed reductive coupling platform. The stereocontrol is essentially governed by the catalyst, on which the α-substituents of the neighboring amino acid elements showed minor effect. The scope of peptides was broad, comprising decapeptides and cyclic pentapeptides. A unique feature of the present work is the viability of modification of the internal sites of the peptides, which stands a sharp contrast to the contemporary studies that focus on the N- or C-terminal peptide α-carbons. This work may provoke a broader interest in peptide backbone modification based on cross-coupling chemistry.