bluuebunny/crossref_metadata_2025 huggingface dataset:
Sexual addiction in drug addicts: The impact of drug of choice and poly-addiction
Authors: Antonio Nelson , Diehl Alessandra , Niel Marcelo , Pillon Sandra , Ratto Lilian , Pinheiro Maria Carolina , Silveira Dartiu , Otani Thais Zelia , Otani Victor , Cordeiro Quirino , Ushida Ricardo
Published: July 2017

Summary Objective: To compare the risk of comorbid sexual addiction in a sample of individuals with a diagnosis of substance dependence, stratifying the sample by drug of choice as well as by mono versus polysubstance addiction. Method: All data were collected at Santa Casa de São Paulo, Brazil. The study sample comprised all alcohol or drug dependents admitted to the Addiction Treatment Unit between November 2013 and August 2014. A generalized linear model with a binomial distribution was performed to compare the odds of having a Sexual Addiction Screening Test (SAST) score greater than 6 points in the subgroups analyzed. Results: A total of 133 participants were included in our analysis, all reporting cocaine/crack and/or alcohol as drug of choice. Polysubstance addicts had a significant higher risk of a positive screening for sexual addiction compared to monosubstance addicts, age-sex adjusted odds ratios of sexual addiction being respectively 2.72 (95CI 1.1-6.71) and 0.37 (95CI 0.15-0.91). The odds of a SAST score greater than 6 was not statistically different between the cocaine/crack and alcohol groups, respectively 0.38 (95CI 0.14-1.02) and 2.67 (95CI 0.98-7.25). We found a significant relation between stronger drug addiction and greater levels of sexual addiction in the cocaine/crack group (p=0.0012), but not in the alcohol group. Conclusion: Our study reinforces the importance of assessing sexual behavior of drug addicts in clinical practice, especially considering users of multiple substances or with severe dependence.
Cardiac remodeling indicators in adolescent athletes
Authors: Castanheira Joaquim , Valente-dos-Santos João , Costa Daniela , Martinho Diogo , Fernandes Jorge , Duarte João , Sousa Nuno , Vaz Vasco , Rama Luis , Figueiredo António , Coelho-e-Silva Manuel
Published: July 2017

Summary Objective: The idea that different sports and physical training type results in different cardiac adaptations has been widely accepted. However, this remodelling process among different sport modalities is still not fully understood. Thus, the current study aims to investigate the heart morphology variation associated with a set of different modalities characterized by distinct models of preparation and different methods and demands of training and completion. Method: The sample comprises 42 basketball players, 73 roller hockey players, 28 judo athletes and 21 swimmers. Anthropometry was assessed by a single and experienced anthropometrist and the same technician performed the echocardiographic exams. Analysis of variance was used to study age, body size and echocardiograph parameters as well as different sport athlete's comparison. Results: Basketball players are taller (F=23.448; p<0.001; ES-r=0.553), heavier (F=6.702; p<0.001; ES-r=0.334) and have a greater body surface area (F=11.896; p<0.001; ES-r=0.427). Basketball and hockey players have larger left auricle diameters compared with judo athletes (F=3.865; p=0.011; ES-r=0.316). Interventricular end-diastolic septal thickness (F=7.287; p<0.001; ES-r=0.347) and left ventricular posterior wall thickness (F=8.038; p<0.001; ES-r=0.362) of the judokas are smaller compared to the mean values of other sports participants. In addition, relative left parietal ventricular wall thickness is lower among swimmers compared with judokas (F=4.127; p=0.008; ES-r=0.268). Conclusion: The major contributors to changes in heart morphology are for the most part associated with sport-specific training and competition and the specific dynamics and adaptive mechanisms imposed by each sport.
Challenges with the public policy of measuring assets to set tariffs in the electricity sector: should someone benefit and someone be sacrificed?
Authors: Andrade Maria Elisabeth Moreira Carvalho , Martins Eliseu
Published: July 2017

ABSTRACT This paper contributes by encouraging discussions about the public policy of setting tariffs for public services based on the value of the investment made by the providers of these services. The purpose of this study was, in an unprecedented way and by combining theories of equity valuation and finance, to identify the asset valuation method that can lead to a fair value and balance between an affordable price for the consumer and an adequate return on investment for the concessionaires. The value assigned to these assets affects the tariff in two ways: (i) via depreciation/amortization, which affects the cost of service; (ii) via the return on investment, which is the portion that corresponds to the investor’s profit. We analyzed the Brazilian electricity sector, in which the rates set by the Brazilian Electricity Regulatory Agency (ANEEL) currently use the new replacement value (NRV) approach. We carried out empirical tests using data available on the ANEEL website from the second cycle periodic tariff review and information obtained in financial statements from 1995 onwards. The analysis included the NVR and restated historical cost (RHC) methods, the latter being updated by the extended consumer price index (IPCA). After the descriptive and statistical analyses, we used the test of means to verify the differences between the variables in terms of NRV vs. RHC. The first conclusion was the absence of a significant difference between the NRV and RHC methods; that is, on average, the replacement price showed no significant difference to what would be the pure and simple restatement of assets. But this was found to hide something relevant, the fact that this average is derived from two main groups: that of the consumers who are paying more for energy services than they should, which constitutes a visible benefit to investors and loss for these consumers, and that of the consumers who are paying less than they should, which benefits them but harms investors.
Uma nova Styrax (Styracaceae) na Amazônia
Authors: Silva Marlene Freitas da
Published: July 2017

Sinopse Com a presente espécie proposta sob o nome de Styrax discolor eleva-se para sete o número de taxas do gênero Styrax (Styracaceae), ocorrentes na Amazônia.
Subsídios para o estudo das Lecythidaceae da Amazônia
Authors: Rodrigues William A.
Published: July 2017

Sinopse As Lecitidáceas Corythophora rimosa W. Rodr., Cariniana pauciramosa W. Rodr., Couratari longipedicellata W. Rodr. e Couratari prancei W. Rodr. são descritas como novas e Corythophora alta R. Knuth, Couratari multiflora (J. E. Smith) Eyma, C. stellata A. C. Smith, C. oligantha Sandwith e C. duckei R. Knuth são discutidas como espécies pouco conhecidas da Amazônia.
Audição em fumantes: uma revisão
Authors: Cavallieri Gabriela Vidotto , Alcarás Patrícia Arruda de Souza , Corazza Maria Cristina Alves , Corazza Luíza Alves
Published: July 2017

RESUMO Dentre os fatores que influenciam o aparecimento de alterações auditivas pode-se citar o tabagismo, já que estudos revelam que o uso do tabaco pode causar um efeito ototóxico na audição. O objetivo do presente estudo foi analisar as produções científicas sobre o efeito do cigarro no sistema auditivo. A metodologia constou de levantamento dos periódicos indexados nas bases de dados, e foram incluídos na revisão de literatura os artigos científicos nacionais e internacionais, publicados em língua portuguesa ou inglesa, entre os anos de 2009 a 2016. Posteriormente a seleção e análise dos artigos na íntegra, foram classificados de acordo com a sua natureza, caracterizando-os em cinco categorias: base de dados, título do artigo científico, autor, ano e país da publicação. Em seguida, foram analisados os critérios utilizados pelos autores dos respectivos artigos, levando em consideração a amostra populacional, a faixa etária e o sexo. Por fim, foram feitas as análises dos exames auditivos utilizados em fumantes e os critérios de exclusão de cada estudo. Assim, por meio dos estudos publicados conclui-se que o uso do tabaco influencia no aparecimento de perda auditiva, prejudicando principalmente os limiares auditivos das altas frequências e inclusive a transmissão neural da informação auditiva.
Efeitos do exercício do trato vocal semiocluído em canudo comercial na voz do professor
Authors: Souza Rafael Cabral de , Masson Maria Lúcia Vaz , Araújo Tânia Maria de
Published: July 2017

RESUMO Objetivo: verificar os efeitos do exercício de fonação em canudo comercial na voz de professores. Métodos: estudo de intervenção, com grupo único de professores, cego ao avaliador. Os participantes foram solicitados a executar o exercício de fonação em canudo imerso a uma garrafa com água no início do turno de trabalho, por quatro semanas consecutivas. Utilizou-se o parâmetro “grau global de severidade” do protocolo Consenso da avaliação perceptivoauditiva da voz (CAPE-V) para a avaliação perceptivoauditiva, o protocolo de autoavaliação índice de triagem de distúrbios de voz (ITDV) e os efeitos vocais autorreferidos na comparação entre os momentos pré e pós-intervenção. Resultados: a média de idade dos professores foi de 45,28 (± 8,48) anos, variando entre 30 e 58 anos, sendo composta, na sua maioria, pelo sexo feminino (79,3%). A frequência de alteração vocal autorreferida foi 58,6%. Houve decréscimo na média dos escores do CAPE-V e do ITDV na comparação antes e após a intervenção com significância estatística (p<0,05). Na pós-intervenção os efeitos autorreferidos ocorridos mais frequentes foram “melhora na voz”, “menor cansaço” (ambos com 37,9%). Conclusão: o exercício com canudo comercial promoveu melhora na voz dos professores e efeitos benéficos autorreferidos e pode ser utilizado como medida protetora.
EXAMES PARA AVALIAR A SENSIBILIZAÇÃO AO ASPERGILLUS FUMIGATUS EM FIBROSE CÍSTICA
Authors: Aguiar Simone Santana , Damaceno Neiva , Forte Wilma Carvalho Neves
Published: July 2017

RESUMO Objetivo: Avaliar os resultados dos exames utilizados para identificar a sensibilização IgE-mediada ao Aspergillus fumigatus em pacientes com fibrose cística. Métodos: Estudo transversal descritivo com amostra de conveniência de 86 pacientes com fibrose cística, acompanhados em Serviço de Referência de Fibrose Cística de hospital universitário terciário. Realizaram-se exames para avaliar sensibilização ao A. fumigatus em pacientes com fibrose cística: IgE sérica total, contagem de eosinófilos sanguíneos, identificação do fungo por swab de orofaringe ou por cultura de escarro, IgE sérica específica e testes cutâneos de hipersensibilidade imediata. Foram comparados os resultados dos diferentes exames realizados. Resultados: Em 33 (38,4%) pacientes com fibrose cística, com faixa etária de 1 a 33 anos (mediana de 8 anos), os resultados dos exames sobre sensibilização IgE mediada ao A. fumigatus foram: em 16 pacientes, aumento de IgE sérica específica (>0,35 kU/L); em 23, positividade aos testes cutâneos; e seis mostraram sensibilização a partir dos dois exames. Foram observados dois pacientes com eosinofilia (>1.000 eosinófilos/mm3) e sete com aumento de IgE sérica total (>1.000 UI/mL), sem que esses apresentassem positividade aos testes cutâneos ou aumento de IgE específica ao A. fumigatus. Em nenhum paciente foi isolado A. fumigatus no swab de orofaringe e/ou na cultura de escarro. Conclusões: Concluímos que, entre os exames para avaliar a sensibilização ao A. fumigatus na fibrose cística, são necessários os teste cutâneos de hipersensibilidade imediata e a dosagem de IgE sérica específica ao A. fumigatus. A eosinofilia sérica e a cultura de secreções respiratórias não foram essenciais neste estudo.
Composición florística y estructura horizontal del bosque semideciduo micrófilo de la reserva ecológica Siboney-Juticí, Cuba
Authors: Cardona Luz Margarita Figueredo , Cantillo Félix Acosta , Ojeda Josefina Blanco
Published: July 2017

Resumen Se caracterizaron la composición florística y la estructura horizontal del bosque semideciduo micrófilo de la reserva ecológica Siboney-Juticí, perteneciente a la reserva de la biosfera Baconao, en el suroriente de Cuba. Se procesaron los datos correspondientes a diez parcelas de 20 m × 50 m, donde a cada individuo se le midió la altura y el diámetro a 1,30 m del suelo. Se calculó el área basal, las abundancias, las frecuencias y las dominancias absolutas y relativas, además del índice de Valor de Importancia por especie y familia. A las matrices de datos se les aplicó el Análisis de Coordenadas Principales como método de ordenación. En el bosque se analizaron 3206 individuos correspondientes a 54 taxones infragenéricos y 27 familias, además se anotaron otras plantas acompañantes. Las especies con mayor número de individuos fueron Coccoloba diversifolia, Bursera simaruba, Sideroxylon salicifolium, Gymnanthes lucida, Nectandra coriacea, Eugenia axillaris y E. monticola, que son las de mayor índice de Valor de Importancia y con tendencia a asociarse entre sí. Se observaron regularidades estructurales y de diversidad entre las parcelas. El estrato arbóreo es denso pero bajo, con escasos emergentes.
Jabot - Sistema de Gerenciamento de Coleções Botânicas: a experiência de uma década de desenvolvimento e avanços
Authors: Silva Luís Alexandre Estevão da , Fraga Claudio Nicoletti de , Almeida Thaís Moreira Hidalgo de , Gonzalez Marcos , Lima Rafael Oliveira , Rocha Mônica Sousa da , Bellon Ernani , Ribeiro Rafael da Silva , Oliveira Felipe Alves de , Clemente Leonardo da Silva , Magdalena Ulises Rodrigo , Medeiros Erika von Sohsten , Forzza Rafaela Campostrini
Published: July 2017

Resumo Sistemas de informação são fundamentais para o gerenciamento dos acervos biológicos das instituições de pesquisas em biodiversidade, uma vez que elas vêm fazendo investimentos significativos nos processos de informatização e digitalização de suas coleções. Os sistemas de bancos de dados de herbários e de jardins botânicos têm evoluído no sentido de disponibilizar online os dados de exsicatas e das coleções correlatas, além de suas imagens. Neste trabalho é apresentada a nova versão do Jabot, o sistema de gerenciamento de coleções botânicas desenvolvido no Jardim Botânico do Rio de Janeiro. O sistema reflete hoje o conhecimento adquirido por uma equipe multidisciplinar composta de botânicos e profissionais da área de computação, em uma década de uso intensivo no gerenciamento do conteúdo digital e na curadoria do herbário.
Aspectos Socioambientais da Comercialização de Pequi em Goiás
Authors: Oliveira Cleiton Silva , Gonçalves Lucas Emanuel Nunes , Coutinho Marcos Pelegrini , Peixoto Ney , Gatto Alcides
Published: July 2017

RESUMO O pequizeiro fornece frutos tradicionalmente utilizados na culinária goiana e regiões do bioma Cerrado. Partindo da análise da comercialização de pequi na Central de Abastecimento de Goiás S/A (Ceasa - GO) e em feiras locais (Ipameri e Pires do Rio - GO), o presente estudo avalia a importância da espécie e ameaças relacionadas ao extrativismo. Os dados revelaram 12 microrregiões produtoras de pequi no estado, sendo comercializados 5,5 mil toneladas de pequi em 2011, com o preço da caixa variando de 25 a 40 reais. Nas feiras, o preço pago por litro em 2010 foi de cinco reais, com um percentual crescente de interessados na venda desse produto não madeireiro. Chama atenção a variação no preço pago ao pequi e mudanças nas regiões produtoras em Goiás, além da aquisição desse produto de outros estados. Para suprir a demanda crescente de pequi, sugere-se, além do extrativismo responsável, o plantio da espécie no Cerrado, em pomares ou sistemas agroflorestais.
Longitudinal distribution of extreme pressures in a hydraulic jump downstream of a stepped spillway
Authors: Novakoski Carolina Kuhn , Hampe Roberta Ferrão , Conterato Eliane , Marques Marcelo Giulian , Teixeira Eder Daniel
Published: July 2017

ABSTRACT The overflow system of a dam safely controls the water level of a reservoir. The design of these structures should predict the damage caused by the action of the turbulent flow to which they are subject to. The combination formed by a stepped spillway followed by a stilling basin promotes a considerable portion of the energy dissipation in the actual chute of the stepped spillway but it is not sufficient to completely avoid the risk of damaging the basin. In this paper, we analyze the longitudinal distribution of extreme pressures in a stilling basin downstream of a stepped spillway. The study was based on the instant pressure data from the tests carried out in a physical model in the Laboratório de Obras Hidráulicas in IPH/UFRGS. Thus, it was found that the pressure behavior is similar to that observed in studies involving smooth chute spillways, except in the area surrounding the base of the stepped spillway, where high pressure fluctuations may occur. This happens as a result of the impact caused by the flow in the dissipation structure, which is not observed downstream of smooth chute spillways due to the existence of a vertical concordance curve between the spillway and the stilling basin.
Impact of alcohol consumption among patients in hepatitis C virus treatment
Authors: VIEIRA-CASTRO Andréa Carvalho Maia , OLIVEIRA Luiz Carlos Marques de
Published: July 2017

ABSTRACT BACKGROUND: Recent studies have questioned the recommendation of abstinence from alcohol for at least 6 months for alcoholic patients to be treated for hepatitis C. OBJECTIVE: The present study aimed to assess the impact of alcohol consumption among patients undergoing hepatitis C treatment. METHODS: In this cross-sectional study, 121 patients [78 (64.5%) men; 28-70 years] were evaluated. They were divided as follows: patients who consumed <12 g of ethanol/day throughout life (Group 1), 12-59 g/day (Group 2) and ≥60 g/day (Group 3). Patients were treated with pegylated-interferon plus ribavirin. RESULTS: These three groups could not be distinguished in terms of the severity of liver fibrosis and frequency of HCV genotype-1 infection. In Group 3, treatment discontinuation (32.4%) was higher than in the Group 1 (9.4%) or Group 2 (0%), it was higher among patients who drank during treatment (66.7% vs 21.4%) and among those who had not been abstinent for at least 6 months (72.7% vs 15.4%). Moderate alcohol drinkers showed good adherence and did not discontinue the treatment. The frequencies of sustained viral response among patients in Group 3 (44.4%) were similar to those in Group 1 (61%) and Group 2 (68.4%). CONCLUSION: Heavy drinkers more often discontinued treatment for hepatitis C, but those that received this treatment had acceptable sustained viral response rates. These results suggest that heavy drinkers should not be systematically excluded from the treatment, but they should be monitored to avoid drinking and abandoning treatment, mainly those who have not been abstinent for at least 6 months.
Clinical Management of Potential Toxicities and Drug Interactions Related to Cyclin-Dependent Kinase 4/6 Inhibitors in Breast Cancer: Practical Considerations and Recommendations
Authors: Spring Laura M. , Zangardi Mark L. , Moy Beverly , Bardia Aditya
Published: July 2017

Aberrations of the cell cycle are pervasive in cancer, and selective cell cycle inhibition of cancer cells is a target of choice for a number of novel cancer therapeutics. Cyclin-dependent kinases (CDKs) are key regulatory enzymes that control cell cycle transitions and the commitment to cell division. Palbociclib and ribociclib are both orally active, highly selective reversible inhibitors of CDK4 and CDK6 that are approved by the U.S. Food and Drug Administration (FDA) for hormone receptor-positive metastatic breast cancer in combination with specific endocrine therapies. A third oral CDK4/6 inhibitor, abemaciclib, received Breakthrough Therapy designation status from the FDA and is also being developed in breast cancer. The most common adverse events associated with palbociclib and ribociclib are hematologic, particularly neutropenia. However, the neutropenia associated with CDK4/6 inhibitors is distinct from chemotherapy-induced neutropenia in that it is rapidly reversible, reflecting a cytostatic effect on neutrophil precursors in the bone marrow. Most hematologic abnormalities seen with CDK4/6 inhibitors are not complicated and are adequately managed with standard supportive care and dose adjustments when indicated. Cytopenias are less prevalent with abemaciclib, although fatigue and gastrointestinal toxicity is more common with this agent. This review focuses on the clinical management of potential toxicities and drug interactions seen with the use of CDK4/6 inhibitors in breast cancer, with a focus on palbociclib and ribociclib, and summarizes practical management strategies for an oncologist.
3D character of backward erosion piping
Authors: Vandenboer K. , van Beek V. M. , Bezuijen A.
Published: July 2017

Backward erosion piping is an important failure mechanism for cohesive water-retaining structures which are founded on a sandy aquifer. Nowadays, piping research and safety assessments are often based on experimental or numerical modelling using arbitrary model widths or even two-dimensional (2D) assumptions. This technical note shows the influence of this limitation through a series of small-scale experiments with varying model widths. The flow pattern proves to be highly three-dimensional (3D), influencing both the pipe geometry and critical gradients leading to piping failure. A 2D model is unable to capture the important aspects of the erosion mechanism and a correction factor needs to be applied if the minimum width for correctly simulating a 3D situation is not accomplished.
Dança e medialidade: para uma discussão ontológica e ética do corpo performativo
Authors: Barros Né
Published: July 2017

A partir dos finais do século XIX podemos assistir a pelo menos duas grandes mudanças nos posicionamentos poéticos sobre a dança, introduzindo, assim, maiores desafios ao pensamento filosófico e estético sobre esta arte. A primeira mudança poderia ser identificada como rutura com um legado, uma rutura coincidente com todos os passos dados pela dança moderna ocidental e, em particular, pela americana. A segunda mudança poderia ser identificada com a expansão das fronteiras da dança, onde se inclui todo o processo de indefinição disciplinar e de género artístico. A rutura e a expansão são mudanças assinaláveis que também podem ser enquadradas num pensamento pós-metafisico. Este domínio expandido e inclusivo do outro pode ainda ser pensado através de uma techné que não se confunde com engenho ou mera capacidade do artífice, ou ainda como eros alienante, mas também como domínio da performatividade enquanto jogo de autorização e desautorização (autoria envolvida no confronto com o outro), tornando-se, por isso, terra de ninguém. Neste campo aberto e indefinido, o corpo dançante revela-se palco político e ético por excelência (performance) e espaço ontológico abrangente (performatividade). É este o âmbito da nossa discussão que encontra na medialidade o domínio comum destas duas abordagens à dança.
Monstros, máquinas e pipocas: teatro do oprimido e protesto de rua
Authors: Barbosa Inês , Ferreira Fernando Ilídio
Published: July 2017

Este artigo parte da experiência do Núcleo de Teatro do Oprimido de Braga no contexto das movimentações levadas a cabo, em Portugal, contra a austeridade, entre 2012 e 2013. Apresenta algumas das intervenções políticas e artísticas do grupo, bem como uma reflexão sobre o seu impacto e limitações. Pretende-se analisar as possibilidades de o Teatro do Oprimido (TO) intervir, influenciar ou potenciar o protesto de rua e, ao mesmo tempo, examinar em que medida pode esta experiência articular e interpelar as duas dimensões de crítica do capitalismo, social e estética, enunciadas por Boltanski e Chiapello na obra O novo espírito do capitalismo. A investigação insere-se numa perspetiva de investigação interventiva e participativa, procurando conceber e situar o TO enquanto ferramenta de ação coletiva e educação crítica, no âmbito das mobilizações sociais contemporâneas.
Mídia, arte e tecnologia: uma reflexão contemporânea
Authors: Lopes Fernando Augusto Silva
Published: July 2017

O presente artigo parte de um relato acerca da mercantilização cultural e seus reflexos na saturação midiática, para então traçar uma reflexão sobre tecnologia, mídia e artes contemporâneas, em especial o papel do corpo nas manifestações artísticas. Busca-se, com este trabalho, ratificar a influência da tecnologia, da massificação midiática e informacional na construção dos valores culturais contemporâneos. Será apresentada também uma reflexão sobre as atuais práticas artísticas contemporâneas como elementos que buscam evidenciar e questionar a influência massificante dos mídia e do mercado. O pano de fundo no qual se desenvolve o presente artigo são as evoluções tecnológicas, que ampliam a mercantilização cultural e tornam possíveis as profundas mudanças sociais e culturais vivenciadas pela sociedade ocidental contemporânea. Por fim é traçada uma breve análise sobre as identidades e diversidades culturais na era da teleinformática.
Printing amphotericin B on microneedles using matrixassisted pulsed laser evaporation
Authors: Sachan Roger , Jaipan Panupong , Y. Zhang Jennifer , Degan Simone , Erdmann Detlev , Tedesco Jonathan , Vanderwal Lyndsi , J. Stafslien Shane , Negut Irina , Visan Anita , Dorcioman Gabriela , Socol Gabriel , Cristescu Rodica , B. Chrisey Douglas , J. Narayan Roger
Published: July 2017

Transdermal delivery of amphotericin B, a pharmacological agent with activity against fungi and parasitic protozoa, is a challenge since amphotericin B exhibits poor solubility in aqueous solutions at physiologic pH values. In this study, we have used a laser-based printing approach known as matrix-assisted pulsed laser evaporation to print amphotericin B on the surfaces of polyglycolic acid microneedles that were prepared using a combination of injection molding and drawing lithography. In a modified agar disk diffusion assay, the amphotericin B-loaded microneedles showed concentrationdependent activity against the yeast Candida albicans. The results of this study suggest that matrix-assisted pulsed laser evaporation may be used to print amphotericin B and other drugs that have complex solubility issues on the surfaces of microneedles.
Synthesis and Solution Properties of Hydrophobically Modified Polysaccharides
Authors: Khutoryanskiy Vitaliy V.
Published: July 2017

Hydrophobically modified polymers are amphiphilic macromolecules mainly constituted of a hydrophilic backbone and hydrophobic side groups. In aqueous solutions these polymers undergo inter- or intra-molecular hydrophobic association, which results in unusual properties useful for a number of practical applications. The areas of application of these polymers include associative thickeners for enhanced oil recovery, pharmaceuticals, personal care formulations, coatings, adhesives, surfactants, emulsifiers, etc. This review presents the analysis of a literature data on preparation of hydrophobically modified polysaccharides (HMP) and their properties in aqueous solutions. Some of the synthetic methods used for hydrophobic modification of non-ionic (cellulose ethers, starch, dextran, pullulan, etc.), anionic (carboxymethylcellulose, hyaluronic
acid, pectic acid, alginic acid, heparin) and cationic  olysaccharides (chitosan) are presented. The methodology used for the investigation of solution properties of hydrophobically modified polysaccharides is discussed. Special attention is paid to aggregate and micelle formation in solutions of hydrophobically
modified polysaccharides, solubilization of hydrophobic compounds, their rheological properties and surface activity. The effects of polymer architecture (level of hydrophobic substitution, nature of hydrophobic groups, molecular weight of a hydrophilic backbone, etc.), concentration, temperature, presence of inorganic salts and organic solvents on solution properties of hydrophobically modified polysaccharides are discussed. Some applications of hydrophobically modified polysaccharides are briefly highlighted.
Application of Interpolymer Complexes of Novel Poly(ampholyteelectrolyte) as Soil Structuring Agents and for Extraction of Radioactive Strontium
Authors: Bimendina L.A. , Yashkarova M.G. , Orazzhanova L.K. , Kudaibergenov S.E.
Published: July 2017

Novel linear copolymer exhibiting poly(ampholyte-electrolyte) behavior was involved into complexation reaction with anionic, cationic and nonionic polymers. Interpolymer complexes were prepared by mixing of aqueous solutions of individual polymers with concentration varying from 10-1-10-4 mol×L-1. The formed interpolymer complexes showed the soil structuring effect and the ability to extract the radioactive strontium from the polluted topsoil of Semipalatinsk Test Site. The mechanism of soil stabilization or aggregation was explained by the fact that the soil particles bearing negative charges interact with positively charged "loops" of interpolymer complexes resulting in the formation of so called "cobweb" (or protective crust) on the soil surface. The effective capturing of radioactive strontium by interpolymer complexes may be connected with formation of more stable ternary polymer-metal complexes. It was demonstrated that: i) interpolymer complexes are the most effective soil structuring agents than that of individual components; ii) the optimal concentration of interpolymer complexes for soil aggregation is 10-2 mol×L-1; iii) pouring of soil surface by interpolymer complexes is more effective than the splashing; iv) the treatment of the soil by already pre-existing interpolymer complexes is most effective than the successive treatment of the soil by individual components; v) the best soil structuring properties were shown for interpolymer complexes stabilized by H–bonds and intra salt bonds.
De nuevo sobre el desistimiento en derecho penal. A propósito de las cuatro reglas sobre la voluntariedad de Restrepo Ramos
Authors: Araque Moreno Diego
Published: July 2017

El presente artículo trata sobre el requisito de la voluntariedad del desistimiento de consumar la conducta punible, examinando a tales efectos las distintas propuestas que se suscitan entre las teorías psicológicas y normativas, optando el autor por una posición mixta que se desarrolla a partir de los criterios de libertad de voluntad y ausencia de coacción como causa de inculpabilidad penal.
El error de prohibición en la justicia indígena
Authors: Chimbo Villacorte Diego Fernando
Published: July 2017

El presente análisis se centra específicamente en el error de prohibición que comete el integrante de una comunidad indígena, no solo porque desconoce absolutamente la antijuricidad de su conducta sino cuando cree que está actuando en estricto apego a sus creencias y costumbres ancestrales, las cuales riñen –en algunos casos– con el derecho positivo. Asimismo, se marca la imposibilidad de imponerle una pena –cuando el delito se comete fuera de la comunidad indígena– o purificación –cuando se comete un acto que altere la paz social dentro de la comunidad indígena– pero sobre todo centra su atención en la imposibilidad de imponerle una medida de seguridad cuando ha cometido un delito fuera de su comunidad, pues al hacerlo lo trata como inimputable y lo regresa a su comunidad, generando así un trato discriminante que le impide, al culturalmente diferente, autodeterminarse.
Mentalna reprezentacja terminu – implikacje dla glottodydaktyki języków specjalistycznych
Authors: Gonigroszek Dorota
Published: July 2017

Celem niniejszego artykułu jest stworzenie modelu reprezentacji umysłowej terminu oraz sformułowanie implikowanych przezeń wskazówek dla nauczycieli języków specjalistycznych. W kolejnych częściach artykułu dokonano charakterystyki języków specjalistycznych, przytoczono definicje terminu, podjęto próbę ustalenia związku między terminem, znakiem językowym a przywoływaną przez niego reprezentacją mentalną (pojęcie, domena, matryca domen, system wiedzy).
Visita de irmãos na unidade de neonatologia do CAISM/UNICAMP: uma proposta de cuidado humanizado junto à família
Authors: Rubio Andreza Viviane , Antunes Gisele do Canto e Silva , Zapparoli Liliane , Massarolo Verônica Cardoso , Amorim Jaqueline Cristina , Santos Laise Potério
Published: July 2017

A chegada de um bebê é frequentemente vivenciada com acentuada intensidade na família, gerando um misto de sentimentos e expectativas. Diante um nascimento de alto-risco, onde o bebê necessita de cuidados intensivos neonatais, há uma mudança brusca na rotina familiar sendo de difícil elaboração e compreensão dos irmãos do mesmo. O programa de visita dos irmãos a unidade neonatal, visa criar um espaço que possibilite a expressão de sentimentos e um momento de maior contato e aproximação das relações familiares. Sendo assim, este trabalho tem como objetivo apresentar a experiência que está sendo desenvolvida na unidade de neonatologia do CAISM/UNICAMP. A visita dos irmãos, ocorre semanalmente às sextas-feiras no período da tarde, em três momentos distintos: 1) avaliação e atendimento dos irmãos pela psicologia, anterior a entrada dos mesmos na unidade, com a utilização de materiais lúdicos, como desenhos, pinturas, histórias e sensibilização do ambiente hospitalar através de fotografias 2) avaliação realizada pela enfermagem com questionário destinado aos pais sobre a condição de saúde destes irmãos; 3) retorno à unidade de psicologia, para fechamento e avaliação da experiência vivenciada pela criança ou adolescente. A partir da experiência na unidade, percebe-se que o período de internação do bebê é um momento crítico também para os irmãos e as visitas auxiliam para proporcionar um espaço de esclarecimento de dúvidas e expressão de sentimentos, de modo que ansiedades e possíveis fantasias sejam amenizadas e elaboradas, além de contribuir para construção e fortalecimento dos vínculos afetivos e interações familiares. A visita dos irmãos junto à unidade é essencial para a diminuição de ansiedades e fantasias tanto dos filhos quanto dos pais, facilitando e fortalecendo os vínculos afetivos.
Resultados da avaliação do grupo multidisciplinar para cirurgia bariátrica no hospital de clínicas da UNICAMP
Authors: Almeida Ana Maria Neder , Cândido Elaine Cristina , Jaroslavski Luciana , Modena Débora Aparecida Oliveira , Baltieri Leticia , Gobato Renata Cristina , Bacan Camila , Gestic Martinho Antônio , Utrini Murillo Pimentel , Cazzo Everton , Chaim Felipe David Mendonça , Chaim Elinton Adami
Published: July 2017

O Ambulatório de Obesidade Mórbida do HC-UNICAMP realiza tratamento de pacientes com obesidade grau I, II e III, tem uma Equipe Multidisciplinar, de médicos, enfermeiros, psicólogos, nutricionistas e fisioterapeutas, com o objetivo de orientar a perda de peso e seus aspectos de forma saudável. As orientações são apresentadas em grupos pré-estabelecidos, por toda Equipe, enfatizando que é necessário participação semanal, pontualidade, cumprimento das orientações, dieta alimentar e perder peso para dar continuidade à sua participação. O objetivo do trabalho foi os pacientes informarem se estão satisfeitos com as orientações recebidas pelos membros da Equipe. Um questionário com 18 perguntas foi aplicado e todos foram convidados a responder, sem a necessidade de identificação, de maneira que pudessem avaliar se o programa está preparando-os para serem operados. Foram analisados 175 questionários respondidos, sendo os resultados apresentados em porcentagens. A maioria dos pacientes identificou-se, e dentre aqueles que se identificaram 137 eram do sexo feminino (85,6%) e 23 eram masculinos (14,4%). Os pacientes também responderam se estão ou não preparados para a cirurgia após participarem das reuniões. A avaliação geral da Equipe e da estrutura do Serviço (sala de reuniões, espaço físico) foi considerada excelente em 31,4%, boa em 65,3%, podem melhorar em 2,8% e ruim em 0,5%. A análise dos resultados evidencia que a Equipe Multidisciplinar tem cumprido o seu papel de maneira efetiva no sentido de orientar adequadamente os obesos, no pré e pós-operatório.
Atuação do serviço social em programa de hemodiálise no HC-UNICAMP
Authors: Santos Jane Khater , Custódio Jackeline
Published: July 2017

O Serviço Social atua com a equipe multiprofissional no Programa de Hemodiálise do Hospital de Clínicas – UNICAMP, afim de facilitar a inclusão do paciente de forma eficaz neste procedimento , através de ações interventivas, garantindo o direito e melhoria de qualidade de vida. A partir de fevereiro do ano de 2013 as solicitações de hemodiálise dos serviços de Enfermaria e Ambulatório, ficaram centralizadas no Serviço Social do CIN - Centro Integrado de Nefrologia. Demonstrar a eficácia da atuação do Serviço Social junto ao programa de Hemodiálise, através do levantamento das solicitações de hemodiálise no período de janeiro de 2015 à junho de 2016. Para elaboração deste estudo foi utilizado estudo quantitativo. Neste estudo foi possível verificar aspectos positivos da intervenção do Serviço Social junto ao programa de Hemodiálise, como: Diminuição do tempo de espera para hemodiálise; Agilização no agendamento de transporte do município para início do tratamento; Mapeamento e estreitamento no relacionamento com as clínicas de hemodiálise. A garantia de direitos, bem como a qualidade de vida do paciente, é pautada no compromisso ético-político, teórico-metodológico e técnico-operativo do Serviço Social.
Assessment of Enzyme Inhibition: A Review with Examples from the Development of Monoamine Oxidase and Cholinesterase Inhibitory Drugs
Authors: Ramsay Rona R. , Tipton Keith F.
Published: July 2017

The actions of many drugs involve enzyme inhibition. This is exemplified by the inhibitors of monoamine oxidases (MAO) and the cholinsterases (ChE) that have been used for several pharmacological purposes. This review describes key principles and approaches for the reliable determination of enzyme activities and inhibition as well as some of the methods that are in current use for such studies with these two enzymes. Their applicability and potential pitfalls arising from their inappropriate use are discussed. Since inhibitor potency is frequently assessed in terms of the quantity necessary to give 50% inhibition (the IC50 value), the relationships between this and the mode of inhibition is also considered, in terms of the misleading information that it may provide. Incorporation of more than one functionality into the same molecule to give a multi-target-directed ligands (MTDLs) requires careful assessment to ensure that the specific target effects are not significantly altered and that the kinetic behaviour remains as favourable with the MTDL as it does with the individual components. Such factors will be considered in terms of recently developed MTDLs that combine MAO and ChE inhibitory functions.
Thick-Skinned and Thin-Skinned Tectonics: A Global Perspective
Authors: Pfiffner O. Adrian
Published: July 2017

This paper gives an overview of the large-scale tectonic styles encountered in orogens worldwide. Thin-skinned and thick-skinned tectonics represents two end member styles recognized in mountain ranges. A thick-skinned tectonic style is typical for margins of continental plates. Thick-skinned style including the entire crust and possibly the lithospheric mantle are associated with intracontinental contraction. Delamination of subducting continental crust and horizontal protrusion of upper plate crust into the opening gap occurs in the terminal stage of continent-continent collision. Continental crust thinned prior to contraction is likely to develop relatively thin thrust sheets of crystalline basement. A true thin-skinned type requires a detachment layer of sufficient thickness. Thickness of the décollement layer as well as the mechanical contrast between décollement layer and detached cover control the style of folding and thrusting within the detached cover units. In subduction related orogens, thin- and thick-skinned deformation may occur several hundreds of kilometers from the plate contact zone. Basin inversion resulting from horizontal contraction may lead to the formation of basement uplifts by the combined reactivation of pre-existing normal faults and initiation of new reverse faults. In composite orogens thick-skinned and thin-skinned structures evolve with a pattern where nappe stacking propagates outward and downward.
In Quest for Improved Drugs against Diabetes: The Added Value of X-ray Powder Diffraction Methods
Authors: Karavassili Fotini , Valmas Alexandros , Fili Stavroula , Georgiou Christos D. , Margiolaki Irene
Published: July 2017

Human Insulin (HI) is a well-characterized natural hormone which regulates glycose levels into the blood-stream and is widely used for diabetes treatment. Numerous studies have manifested that despite significant efforts devoted to structural characterization of this molecule and its complexes with organic compounds (ligands), there is still a rich diagram of phase transitions and novel crystalline forms to be discovered. Towards the improvement of drug delivery, identification of new insulin polymorphs from polycrystalline samples, simulating the commercially available drugs, is feasible today via macromolecular X- ray powder diffraction (XRPD). This approach has been developed and is considered as a respectable method, which can be employed in biosciences for various purposes such as observing phase transitions and characterizing bulk pharmaceuticals. An overview of structural studies on human insulin complexes performed over the past decade employing both synchrotron and laboratory sources for XRPD measurements, is reported herein. This review aims to assemble all recent advances in diabetes treatment field in terms of drug formulation, verifying in parallel the efficiency and applicability of protein XRPD for quick and accurate preliminary structural characterization in large scale.
The Regulation of Sustainability Information–The Contribution of Directive 2014/95
Authors: Carini Cristian , Rocca Laura , Veneziani Monica , Teodori Claudio
Published: July 2017

The Directive 2014/95, in force in 2017, is the first European step that requires mandatory non-financial information to undertakings (all “public interest entities” with more than 500 employees). The regulation is concerning sustainability information as environmental, social and employee, human rights and anti-corruption and bribery matters and disclosure of diversity policy for board members. The study, in the strand of the regulation of accounting, part of the broader field of research into accounting regulation, contributes to the debate on the quality of regulation, in this specific case referred to sustainability disclosure. The regulation of sustainability matters is studied in literature broadly in a post-implementation phase and at national level. This research, instead, aims to analyse, through the causal chain of regulatory policy, in the ex-ante stage, the quality of the regulation and, at least, the usefulness of the normative pressure. The Oil & Gas sector is chosen as sample of the study, because it is one of the most advanced sectors in sustainability disclosure. The examination of the law, in terms of content requirements (what) and location of information (where), is the basis to apply the disclosure-scoring system, a partial form of content analysis, to the reports of the sample. The findings reveal a good level of completeness of non-financial information, however, there are some areas that have to be improved to reach the requests of the Directive. Results show also the presence of overlap between financial reports and sustainability ones. In conclusion, the regulation is useful to prompt undertakings to reflect on their reporting and so doing improve their sustainability approach.
Pengaruh Perkembangan Kegiatan Perdagangan dan Jasa terhadap Perubahan Penggunaan Lahan di Kawasan Solo Baru
Authors: Arifia Dina , Soedwiwahjono Soedwiwahjono , Utomo Rizon Pamardhi
Published: July 2017

Solo Baru region has a very strategic location and were originally intended for residential areas, but then experienced a rapid development of economic activities. The development of economic activity is the most visible trade activities and services that continue to increase precisely since 2002. The development of trade and services activities is of course have an influence on land use changes that occur rapidly in Solo Baru region. Based on these issues, the formulation of the problem in this research is how the influence brought about by the development of the activity of trade in services to changes in land use. In line with these problems, this study aims to determine the effect of the development of trading activities and services to changes in land use Solo Baru Region. The method used is quantitative descriptive to determine the level of development to later described spatially. These results indicate that the development of trade and services activities has encouraged the development of other activities either similar activities (commercial) as well as supporting activities (housing, public services, and industry) so the impact on the provision of land. The need for this land that drives the changes in land use, both in terms of area, intensity, and land use patterns are formed. Developments are vertically making it more influential in the development of land compared to the intensity of the land area. Besides land development patterns that are formed are random pattern of development as the region woke formed does not have a specific shape (sporadic) and develop segmental.

 

Keywords: Activities Development, Trade and Services Activity, Land Use Change
Hubungan Tingkat Kegiatan Pasar Tradisional Baru terhadap Perubahan Tata Guna Lahan Perdagangan Jasa di Kota Surakarta
Authors: Afriliasari Fimalananda , Utomo Rizon Pamardhi , Yudana Galing
Published: July 2017

Surakarta as a city of culture and commerce services has many economic facilities to develop the trade sector. One of those economic facilities is traditional market. Traditional markets that has just been made by the government to regulate activities of street vendors, hereinafter in this research is referred to as new traditional market. Among four new traditional markets in Surakarta have different activity crowds. Since new traditional markets were established, there was development of trade and services activities around it. In addition, there is also a theory stating that economic activities will cause physical development of city, especially in terms of trade and services land use. So this research has objective to find out how the correlation between levels of activity on new traditional markets in Surakarta with changes in land use around it becomes trade and services functions. This research uses a deductive approach and classified as correlational study. Research analysis technique used is: scoring analysis to assess level of activity on new traditional markets and qualitative relationship matrix analysis to assess correlation between level of activity on new traditional markets with each changes in land use of trade and services sub-variable. The results obtained that level of activity on all new traditional markets in Surakarta has strong correlation to changes in type of trade and services land use around it, has moderate correlation to changes in basic building coefficient, also has strong correlation to changes in floor building coefficient around it.

 

Keywords: land use, new markets, trade and services