bluuebunny/crossref_metadata_2025 huggingface dataset:
Correlation between PD-L1 and Ki-67 Expression at various T-stage Clear Cell Renal Cell Carcinomas
Authors: Setijo Rahaju Anny , Rahniayu Alphania , Hary Kusumastuti Etty , Adi Wiratama Priangga , Kusumadewi P. Thaib Pamela , Takaria Mimi
Published: February 2024

Renal cell carcinoma (RCC) is a malignant neoplasm originating from renal epithelium, with the clear cell renal cell carcinoma (ccRCC)being the most common type (80%) and the most common cause of death among other types of kidney cancer. Pathological stage is an important parameter that affects ccRCC survival, followed by nuclear grade. Pathological staging of RCC according to the AJCC (American Joint Committee on Cancer) TNM system 8th edition is based on local extension of the main tumor (T), involvement of lymph node (N), and metastasis (M). Ki-67 is a marker of proliferation used to assess tumor grade. High Ki-67 correlates with poor prognosis, advanced clinical and pathological features, thus Ki-67 can be used as a biomarker in the management of RCC.Ki-67 is routinely used to see the proliferation index in various cases of malignancy, but not in kidney malignancy. Programmed death ligand 1 (PD-L1) acts as a negative regulator of T cell-mediated anti-tumor immune responses. PD-L1 is expressed on T cells, B cells, macrophages, dendritic cells, endothelial cells and in various tumor cells including ccRCC. This study aims to determine the correlation between the expression of PD-L1 and Ki-67 in various T-stage clear cell renal cell carcinomas. Material and Method: This was an observational analytical study with cross-sectional approach toward 52 cases of ccRCC whose diagnosis was made histopathologically at the Anatomical Pathology Installation of Dr. Soetomo General Academic Hospital Surabaya from January 2014 to December 2020. Immunohistochemical stainingwas carried out using Ki-67 and PD-L1 antibodies, followed by an assessment using a scoring system. T-stage data were obtained from the patients’ medical recordswhich were then analyzed statistically with the Spearman test. Result: The study included 52 cases of ccRCC obtained from nephrectomy specimens at RSUD dr. Soetomo between 2014–2020. The age distribution of the subjects was 29–69 years and the mean and median age was 53 years. The ratio of male patients compared to female patients was 2.5:1. The majority was stage T2 (50%). Statistical test results showed no correlation between the expression of PD-L1 and Ki-67 in various T-stage clear cell renal cell carcinomas (p=0.965 and p=0.680). Conclusion: This study showed no correlation between the expression of PD-L1 and Ki-67 in various T-stage clear cell renal cell carcinomas. Nonetheless PD-L1 can be considered as an important biomarker with a poorer prognosis and aggressive clinicopathological findings in patients with RCC.
Blockchain and Smart Contracts: Revolutionizing Auditing and Financial Transactions
Authors: Vanithamani M R Dr. R. Nadanasabai, Dr. Saikumari.V, Dr , Ranjan Mishra Dr. K. C. Prakash, Dr. Anurag Aeron, Dr. Biswo
Published: February 2024

This paper explores the potential of blockchain technology to transform the accounting system. Blockchain technology is a distributed data set that records all exchanges in a shared organization, allowing for secure and dispersed transactions without relying on a centralized authority. It identifies challenges such as scalability, flexibility, suitable architecture, and cybersecurity. To fully integrate blockchain into an accounting ecosystem, a consensus between regulators and auditors is needed. The paper also provides an overview of how blockchain can improve information quality, highlighting its decentralization and transparency, which could significantly enhance the accounting system. In view of the discoveries from the overview, both brilliant agreement difficulties and open issues are distinguished to be tended to in additional examinations. At last, we talked about future patterns of shrewd agreements. This study offers educational help to partners intrigued by the exploration of shrewd agreements.
Impact of Effective Corporate Governance on Employer Branding of India: An Empirical Study
Authors: Ashish Kaushal, Vandana Devi Anish Kaushal,
Published: February 2024

Employees and consumers alike have become brand aware due to the growing importance of branding. Examining how company branding affects workers' dispositions is the goal of this research. An empirical investigation is what this is. A total of 140 individuals working for private banking institutions provided their data. The research also makes use of secondary data culled from various online sources, such as journals, publications, reports, and websites. Key factors that influence employer brand are highlighted in this research. It also shows how different aspects of branding influence workers' attitudes. Positive employer-employee relationships may be easier to achieve if management practitioners use the study's findings to inform their strategy.
Advanced Determination of Temperature Coefficients of Photovoltaic Modules by Field Measurements
Authors: Schneider Andreas , Chochollek Julia , Nierhoff Thomas
Published: February 2024

In this work data from outdoor measurements, acquired over the course of up to three years on commercially available solar panels, is used to determine the temperature coefficients and compare these to the information as stated by the producer in the data sheets. A program developed in MatLab App Designer allows to import the electrical and ambient measurement data. Filter algorithms for solar irradiance narrow the irradiance level down to ~1000 W/m2 before linear regression methods are applied to obtain the temperature coefficients. A repeatability investigation proves the accuracy of the determined temperature coefficients which are in good agreement to the supplier specification if the specified values for power are not larger than -0.3%/K. Further optimization is achieved by applying wind filter techniques and days with clear sky condition. With the big (measurement) data on hand it was possible to determine the change of the temperature coefficients for varying irradiance. As stated in literature we see an increase of the temperature coefficient of voltage and a decline for the temperature coefficient of power with increasing irradiance.
Rhetorical Contrast Between Turkey and the Ottoman Empire: ‘Modern’ Turkey Versus ‘Unmodern’ Ottoman Empire
Authors: Goksel Reyhan Kadriye
Published: February 2024

In its first decades, the Turkish Republic attempted to create a new national identity that differed from the identity of the Ottoman Empire in socio-cultural, bureaucratic, administrative and legal terms. This attempt led to the creation of a rhetoric of difference between Turkey and the Ottoman Empire. This article argues that the rhetorical rupture between Turkey and the Ottoman Empire was reflected in the Turkish press discourse of the early republican years. Applying the Vienna School of Discourse-Historical Approach (Reisigl & Wodak 2001; Wodak 1990, 1994), this article will analyze the discursive and rhetorical strategies of the editorial published by M. Nermi in Cumhuriyet newspaper in 1931 to show that the editorialist M. Nermi strove to explain the administrative and perspective difference of Turkey from the Ottoman Empire. This article will show what kind of persuasive techniques the editorialist used to make the readers agree with his arguments.
Expressão antigênica e diferenciação morfolôgica de neoplasias mamárias: um estudo comparativo
Authors: Pestana Cynthia Bomfim , Almeida Paulo Cyrillo Cardoso de
Published: February 2024

Foram selecionados quatro carcinomas ductais invasivos de mama com graus de anaplasia progressivos e testados por métodos imuno-histoquímicos para marcadores de diferenciação mamária com o objetivo de verificar a correlação entre grau histológico e a presença desses marcadores. Foram utilizados anticorpos contra alfa-Iactoalbumina, lactoferrina, caseína, componente secretor, antígeno epitclial de membrana e antígeno carcinoembriônico. A neoplasia mais diferenciada resultou positiva para todos os antígenos pesquisados, enquanto a neoplasia menos diferenciada resultou negativa, com exceção da alfa-Iactoalburnina, As neoplasias com diferenciação intermediária apresentaram coloração focal nas áreas mais diferenciadas da lesão. Uma correlação entre a expressão dos antígenos de diferenciação celular mamária e uma boa diferenciação histológica foi verificada para a maioria dos marcadores utilizados.
Análise de alguns parâmetros envolvidos com o ensaio de DNA polimerase do vírus da hepatite B
Authors: Miyamoto Yuriko , Pinho João Renato Rebello
Published: February 2024

O micrométodo para detecção da atividade da DNA polimerase do Vírus da hepatite B descrito por LIN et alii foi modificado, e realizou-se um estudo comparativo entre as duas técnicas. Além disso, foram comparados dois tipos diferentes de papel de filtro, o GF/C e o AP20. Todos os testes apresentaram resultados viáveis; ademais, pudemos verificar que a técnica de Lin modificada e o filtro AP20 mostraram maiores diferenciais, sendo recomendados para este tipo de trabalho.
Avaliação de um método simples e econômico para a metilação de ácidos graxos com lipídios de diversas espécies de peixes
Authors: Maia Everaldo Lima , Rodriguez-Amaya Délia B.
Published: February 2024

Existem diversas técnicas disponíveis para a preparação de ésteres metílicos de ácidos graxos, cada uma tendo vantagens e desvantagens. O método de METCALFE et alli utiliza o reagente BF3-MeOH que é caro e importado, o método de HARTMAN & LAGO emprega reagentes comuns, mas requer mais vidrarias e maiores manipulações. Aproveitando os aspectos vantajosos dos dois métodos citados, foi experimentado um método que proporciona rapidez, simplicidade e baixo custo. Utilizou-se o reagente esterificante de HARTMAN & LAGO e as demais etapas descritas por METCALFE et alii, sendo que as reações de hidrólise e esterificação foram realizadas em tubo de ensaio. O método proposto foi comparado com o método de METCALFE et alii, utilizando os lipídios musculares de pacu, Piaractus mesopotamicus e sardinha, Sardinella brasiliensis. Para a separação e quantificação dos ácidos graxos foi utilizada cromatografia gasosa de alta resolução. Não houve diferença significativa ao nível de 5% nas porcentagens de 18 ácidos graxos de pacu. De 36 ácidos graxos de sardinha, uma diferença significativa a nível de 5% foi observada em apenas dois. Mesmo para estes dois ácidos graxos, a diferença não foi significativa a nível de 1%. Portanto, os dois métodos são equivalentes. Estes dois métodos também apresentaram resultados semelhantes para os lipídios de curimbatá, tílápía e tambaqui, demonstrando a alta aplicabilidade do método proposto.
Presença de ácaros em doces de amendoim e de leite vendidos por ambulantes na cidade de São Paulo
Authors: Franzolin Márcia Regina , Baggio Domingos , Correia Marlene , Rodrigues Regina Maria Morelli Silva
Published: February 2024

No período de Janeiro/1992 a Janeiro/1993 foram analisadas 351 amostras de doce de amendoim em tablete e 157 amostras de doce de leite em tablete adquiridas mensalmente em dez barracas de ambulantes de doces, distribuídas em 4 regiões da cidade de São Paulo, para avaliar a situação de contaminação dos doces pelos ácaros, durante as 4 estações do ano. Estas amostras foram examinadas sob microscópio estereoscópico, percorrendo toda a superfície da amostra, no ato da aquisição, e semanalmente até completar 28 dias, mantidas em ambiente e em estufa BOD a 25°C e 75% U.R.A.. Outra parte da amostra foi selada em saco plástico e analisada após 90 dias de armazenamento. Cerca de 18,2% das amostras de doce de amendoim e 13,5% das amostras de doce de leite foram encontradas parasitadas por ácaros. Das espécies encontradas, 98,9% foram Tyrophagus putrescentiae Schrank, 0,9% Blattisocius tarsalis Berlese, 0,2% Blomia tropicalis Bronswijk, Cock e Oshima e 0,04% Suidasia pontifica Oudemans. Quando em ambiente, as amostras de doce de amendoim tiveram um número médio de 0,3 ácaros, e em estufa 4,4; enquanto que, para as amostras de doce de leite, 4,5 ácaros em média em ambiente e 3,1, em estufa. Os ácaros foram encontrados em número maior no 21° e 28° dias de análise, sendo que o exame no ato foi negativo, o que indica que havia ovos na amostra, e que com o tempo e em condições ótimas, vieram a se desenvolver, salientando a importância da incubação de uma amostra para exclusão da hipótese da presença de ácaros. As amostras de 90 dias de armazenamento apresentaram um número médio de ácaros bem elevado: 7,4 ácaros para doce de amendoim, e 19,9 ácaros para doce de leite, mostrando assim que um longo armazenamento é propício para que haja um aumento populacional de ácaros a partir de ovos presentes na amostra. As épocas do ano que apresentaram maior percentual de amostras positivas para ácaros foram: inverno: 34,9% e verão: 18,8%. No inverno, a percentagem deveria ser menor, pois as condições de temperatura e umidade são desfavoráveis para o crescimento dos mesmos, podendo-se, então, deduzir que essas amostras foram armazenadas por tempo prolongado, e que os ovos remanescentes das demais estações, mais favoráveis para proliferação acariana, eclodiram e se desenvolveram no inverno.
Estudo morfológico de aspirados de medula óssea em pacientes com Síndrome da Imunodeficiência Adquirida
Authors: Barreto José Augusto , Munhoz Marcos Antonio Gonçalves
Published: February 2024

Entre junho e novembro de 1992,estudamos 42 aspirados de medula óssea de pacientes com Síndrome da Imunodeficiência Adquirida (SIDA), grupo IV-C (classificação CDC, 1986), para avaliarmos as alterações morfológicas, qualitativas e quantitativas, decorrentes desta síndrome. Os critérios clínicos para a realização dessas punções foram: febre persistente, anemia, leucopenia, trombocitopenia ou uma combinação dessas anormalidades. Na medula óssea encontramos predomínio de hipocelularidade (71,4%), alterações mielodisplásicas em todos os casos, eosinofilia (19,0%), plasmocitose (45,2%), linfopenia (21,4%) e macrófagos em número aumentado (16,7%). No sangue periférico observamos anemia (81,0%), leucopenia (59,5%), neutropenia (42,9%), linfopenia (88,0%), plaquetopenia (33,3%) e pancitopenia (38,0%). As causas dessas anormalidades são múltiplas: infecções oportunistas, medicamentos mielosupressores, mecanismos imunológicos e ação direta do HIV sobre células progenitoras da medula óssea e células maduras do sangue periférico.
Avaliação da qualidade do café torrado e moído e torrado processado na região de Campinas, Estado de São Paulo
Authors: Ap. Ressinetti Pedro Nilva , Irene Cibela Badolato Maria , Pereira da Silva Freitas Valéria , Flávio Teixeira Chiarini Paulo
Published: February 2024

Foram analisadas 49 amostras de café torrado e moído, processados na região de Campinas, Estado de São Paulo, sendo determinados os teores de cafeína, extrato aquoso, resíduo mineral fixo, resíduo mineral fixo insolúvel em ácido clorídrico e impurezas (cascas e paus). Todas as amostras (100%) estavam de acordo com a legislação em vigor quanto ao exame químico e apenas 2 amostras (4%) apresentaram teores de cascas e paus acima de 1%, portanto, em desacordo com a legislação em vigor.
Avaliação das características físico-químicas do leite de coco comercializado a varejo com relação aos parâmetros legais vigentes
Authors: Tavares Mário , Regina P. do Amaral Mello Márcia , Sorrentino Minazzi-Rodrigues Regina , Duarte Marilda , Camilo Campos Norberto
Published: February 2024

Com o objetivo de avaliar as características fisicas e químicas de leite de coco, com relação aos parâmetros fixados pelas normas técnicas vigentes no Brasil e à classificação sob a qual os produtos são comercializados, foram analisadas 62 amostras de leite de coco, de 15 diferentes marcas, todas com data de fabrícação e/ou lote diferentes entre si, disponíveis no comércio das cidades dc São Paulo, Santos, SãoVicente(SP) e Recife(PE). As determinações realizadas incluíram acidez, lipídios(Gerber), sacarose e pesquisa de ranço, segundo os métodos descritos nas "Normas Analiticas do InstitutoAdolfo Lutz" (1985). Das 62 amostras analisadas, 24 (39%) estavam em desacordo quanto ao teor de lipídios, quer seja declarado ou correspondente à classificação. Relativamente aos teores de acidez, todas as amostras apresentaram-se dentro do limite estabelecido, além de reação de ranço negativa. Com respeito à sacarose, os dados obtidos poderão servir de subsídios quando da revisão da atual legislação. Observou-se, quanto à denominação dos produtos constante do rótulo, o uso de 5 diferentes classificações, dentre as quais, apenas a classificação "natural" consta da legislação.Assim sendo, sugere-se uma ação fiscalizadora mais intensa, principalmente no que diz respeito à denominação do produto na rotulagem bem como uma revisào da norma técnica em vigor...
Defumação líquida da truta arco-íris (Oncorhynchus mykiss): efeitos do processamento e da estocagem nas propriedades físicas, químicas e sensoriais
Authors: Morais Cleso , Mourão Machado Thais , Tavares Mário , Takemoto Emy , Yuco Yabiku Helena , Satou Martins Maristela
Published: February 2024

Com o objetivo de avaliar os efeitos do processamento e da estocagem na qualidade do produto defumado, foram realizados ensaios de defumação líquida com filés de truta arco-íris. Utilizou-se dois procedimentos (com e sem cocção parcial do pescado), que foram comparados entre si durante a estocagem a -IO"C por 150 dias. Aroma natural de fumaça líquida foi aplicada diretamente nos filés na etapa de salmouragem, após o que um lote (sem sofrer cocção) foi imediatamente congelado em túnel, com circulação forçada de ar, operando a -30°C, enquanto que o outro sofreu cocção, secagem e congelamento a -30"C. Ambos os lotes foram embalados, individualmente, em sacos plásticos logo após o congelamento, sendo avaliados nos período de zero, 60, 90 e 150 dias de estocagem, através de análises físicas, químicas e sensoriais.Os parâmetros analisados foram: umidade, cinzas, cloretos, bases voláteis totais (BVT), reação de Kreis (ranço), reação de Éber para gás sulfidrico, pH e 3,4 benzopireno. O teor de umidade em todas as amostras que sofreram cocção parcial manteve-se abaixo de 65%, que é o recomendado para tal tipo de produto. Os valores de pH mostraram que nenhum dos produtos processados era mais ácido do que o outro. Os resultados da avaliação sensorial das amostras sem cocção parcial sugerem que, além da textura macia, a concentração de cloreto de sódio (sal) preferida pelos provadores, na fração aquosa, oscilou entre 3,68g% e 4,72g%. As reações negativas, tanto de Kreis como de Éber, revelaram a boa estabilidade dos produtos processados, ao longo do período deestocagem. No entanto, contatou-se níveis relativamente elevados de BVT em todas as amostras analisadas. Por outro lado, não foi detectado o 3,4 benzopireno em nenhuma delas. Os resultados obtidos apontam os efeitos benéficos (sensorial e toxicológico) do citado aroma sobre o produto.
Efeito do aquecimento na biodisponibilidade dos carotenóides do azeite de dendê adicionado ao óleo de soja, em ratos
Authors: Varella Morandi Márcia , Maria Duarte Fávaro Rosa , Afonso Jordão Jr. Alceu , Vannucchi Helio , Eduardo Dutra de Oiveira José
Published: February 2024

O óleo de palma, conhecido no Brasil como azeite de "dendê" é o óleo extraidopolpa do fruto da palmeira Elaeis guineensis Jacq, sendo uma fonte muito rica de pró-vitamina A, especialmente B-caroteno. Nesse estudo comparou-se a biopotência do azeite de dendê como fonte de próvitamína A em relação ao B-caroteno sintético, avaliando-se também o efeito do processamento térmico sobre a biodisponibilidade da vitamina A em ratos. Foram utilizados três grupos de seis animais, previamente deficientes em vitamina A. Os animais receberam, por 20 dias, dietas contendo óleo de soja enriquecido com B-caroteno sintético, azeite de dendê sem aquecimento ou então azeite de dendê submetido ao aquecimento de 100°C por 20 minutos.Todas as dietas continham teoricamente 4 ER/gramade dieta. A concentração hepática de vitamina A foi semelhante nos grupos controle e naquele que recebeu azeite de dendê sem aquecimento prévio (185,72 ± 25,40 e 150,17 ± 33,08 ug/g de tecido, respectivamente). O grupo no qual o azeite de dendê sofreu processamento térmico mostrou um valor menor de vitamina Ahepática em relação ao controle (144,80 ± 16,84 e 185,72 ± 25,40 ug/g de tecido, respectivamente). Os resultados demonstram a viabilidade do azeite de dendê como fonte pró-vitamínicamesmo sob processamento térmico, visto que os animais do grupo que receberam azeite de dendê previamente aquecido armazenaram quantidades significativas de vitamina A hepática.
Rezension von: Palmer, Nigel F. u.a. (Hrsg.), Württemberg als Kulturlandschaft
Authors: Kottmann Carsten , Palmer Nigel F.
Published: February 2024

Württemberg als Kulturlandschaft. Literatur und Buchkultur an Klöstern und Höfen im späten Mittelalter Hrsg. von Nigel F. Palmer, Peter Rückert und Sigrid Hirbodian. Verlag de Gruyter Berlin/Boston 2023. 549 Seiten. Hardcover 119,95 €. ISBN 978-3-11-077824-3
Lead concentration in different trophic levels: experimental analysis
Authors: Lima Wilson Figueiredo de , Gutjahr Ana Lúcia Nunes , Braga Carlos Elias de Souza
Published: February 2024

This study aimed to experimentally evaluate the capacity of lead (Pb) accumulation and passage at different trophic levels. To do so, the aquatic macrophyte M. linifera, grasshoppers of the T. surinama species, and Theraphosa sp. spiders were collected and subjected to experiments 1, 2, and 3 with 1 g.L-1, 0.1 g.L-1 of Pb, and without lead, respectively. After analyzing the results using a flame atomic absorption spectrometer, the presence of Pb was detected in the analyzed trophic levels. The highest concentration of Pb was found in the aninga root in experiment 2 (219,705.6 mg.Kg-1), and the lowest concentration was found in the leaf of experiment 1 (79.4 mg.Kg-1). The grasshoppers in experiment 1 and 2 did not show traces of Pb, only in their feces, the highest being 201.98 mg.Kg-1 and the lowest being 8.74 mg.Kg-1.Traces of Pb were also found in the spiders, with the highest concentration detected in experiment 1 (7.42 mg.Kg-1). The study revealed an increase in Pb concentration in the experimental food chain across the three trophic levels. T. surinama acted as a lead desconcentrator in the food chain, returning the ingested lead to the environment, creating a cycle in the aquatic environment where lead can be reabsorbed by the plant.
Evaluation of the biological safety of the extract of Senegalia bahiensis (Benth.) Seigler & Ebinger
Authors: Santos Elvis Bezerra , Da Silva Nabuêr Francieli , Castanha Elisângela Ramos , Silveira Filho Vladimir da Mota , Falcão Rosângela Estevão Alves
Published: February 2024

The use of medicinal plants is recurrent for the treatment of various diseases, however, despite being a natural resource, they can cause adverse effects, depending on the way they are administered. Senegalia bahiensis is an angiosperm belonging to the Fabaceae family, with no records in the literature about its cytotoxic potential. The objective of this study was to evaluate the biological safety of S. bahiensis extract through cytotoxicity assays: hemolytic activity and osmotic fragility. At a concentration of 1000 ug/mL, the extract showed a high hemolytic rate for types A and O erythrocytes. The hemolytic activity was low at other concentrations, while the extract's concentrations of 10 and 100 ug/mL used for the anti-hemolytic assay did not protect erythrocytes against osmotic lysis. The results demonstrated that S. bahiensis extract is not safe at the highest concentrations tested in vitro, moreover, it did not show a cytoprotective effect. Therefore, further investigation regarding the cytotoxicity of this specimen is necessary, and its use must be cautious.
PENGARUH SIKAP, NORMA SUBJEKTIF, DAN KONTROL PERILAKU PERSEPSIAN TERHADAP KEPATUHAN PAJAK UMKM DI PAMEKASAN
Authors: Ustman Ustman
Published: February 2024

This research aims to test MSME Taxpayer Compliance in Pamekasan. To test tax compliance, one can approach the economic and psychological factors of a taxpayer himself. This research uses a psychological approach, namely attitudes, subjective norms, and perceived behavioral control. This research uses quantitative data by distributing questionnaires as the primary data source and containing various types of tests. Instrument test, classical assumption test and multiple linear regression test. This research obtained the following results: subjective norms have a partially positive and significant effect on taxpayer compliance, attitude has a partially positive and significant effect on taxpayer compliance, behavioral control has a partially negative and significant effect on taxpayer compliance, and subjective norms, attitudes, and perceived behavioral control simultaneously have a positive and significant effect on taxpayer compliance.
Identifikasi Berat Jenis dan Modulus Elastisitas Jenis Kayu yang di Perdagangkan di Provinsi Gorontalo
Authors: Usman Sartika Dewi
Published: February 2024

Kayu merupakan salah satu bahan alam yang memiliki peranan penting dalam berbagai sektor, termasuk konstruksi. Berat jenis kayu adalah ukuran dari kerapatan atau massa jenis kayu tersebut. Dalam konteks penelitian ini, berat jenis kayu merupakan parameter penting yang dapat memberikan informasi tentang kekuatan dan keawetan kayu. Modulus elastisitas, di sisi lain, mengukur kekakuan kayu dan kemampuannya untuk menahan gaya atau tekanan. Informasi ini sangat diperlukan dalam perencanaan desain struktural, khususnya dalam pemilihan kayu yang tepat untuk aplikasi tertentu. Penelitian ini bertujuan untuk mengidentifikasi berat jenis dan modulus elastisitas jenis kayu yang diperdagangkan di Provinsi Gorontalo. Berdasarkan pengujian secara fisis melalui pengukuran kadar air selanjutnya diperoleh berat jenis kayu dan modulus elastisitas maka dihasilkan kode mutu dari masing-masing kayu yang diuji yaitu: kayu cempaka = E9, kayu albasia=E10, kayu mahoni = E10, kayu jati merah=E12, kayu lea=E13, kayu deu=E10, kayu lasi = E13, kayu latung=E7, kayu jati putih = E19 dan kayu agatis = E9. Berdasarkan kelas kuat kayu (PKKI, 1961) dari masing-masing kayu yang diuji yaitu : kayu cempaka = III, kayu albasia=III, kayu mahoni = III, kayu jati merah=II, kayu lea=I, kayu deu=III, kayu lasi = I kayu latung=IV, kayu jati putih = III dan kayu agatis = III.
PENGGUNAAN ALGORITMA METAHEURISTIK UNTUK OPTIMASI FINANCE BASED SCHEDULING
Authors: Reynaldo Ambrosius Matthew Junius , Prayogo Doddy
Published: February 2024

Keberhasilan proyek konstruksi dipengaruhi oleh penjadwalan proyek dan kondisi finansial kontraktor. Kedua faktor ini perlu terintegrasi dengan baik sehingga tercapai penjadwalan proyek yang mempertimbangkan kondisi keuangan perusahaan kontraktor. Konsep finance-based scheduling mengintegrasikan kedua faktor tersebut dan penelitian ini berusaha melakukan proses optimasi dengan menggunakan algoritma metaheuristik. Pemilihan konsep finance-based scheduling bertujuan untuk menghindarkan proyek dari keterlambatan dan pembengakakan biaya. Proses optimasi finance-based scheduling meminimalkan total durasi proyek, besarnya pinjaman dana, dan besarnya bunga pinjaman dari bank secara simultan. Hasil dari proses optimasi yang dilakukan pada studi kasus proyek SOHO X di Surabaya adalah berbagai skenario penjadwalan proyek yang dapat dipilih oleh kontraktor sesuai dengan tingkat kepentingannya
PENGARUH BLENDED LEARNING TERHADAP KEMAMPUAN PEMECAHAN MASALAH MATEMATIKA SISWA SMA
Authors: Jamaluddin Muhammad
Published: February 2024

Penelitian ini bertujuan untuk menguji pengaruh blended learning terhadap kemampuan pemecahan masalah siswa. Penelitian ini menggunakan metode quasi eksperimen yang dilakukan pada siswa SMA semester genap 2022/2023. Subyek penelitian adalah siswa kelas X. Kelompok eksperimen diberikan penerapan blended learning dan pada kelas kontrol diterapkan dengan menggunakan direct instruction. Instrumen tes kemampuan pemecahan masalah. Sampel yang digunakan dipilih dengan menggunakan teknik random sampling. Teknik analisis data menggunakan Analysis of Covariance (ANCOVA).Hasil pengujian menunjukkan bahwa siswa pada kelas blended learning memperoleh skor kemampuan akhir pemecahan masalah lebih besar dibandingkan pada kelompok direct instruction setelah skor awal dikontrol (sig. < 0,000), dengan nilai partial eta square = 0,759. Hasil penelitian tersebut menunjukkan bahwa blended learning, dapat memberikan kesempatan kepada guru untuk memfasilitasi kegiatan pembelajaran dengan kondisi lingkungan dan fasilitas pembelajaran yang memungkinkan mereka mencapai tujuan pembelajaran secara optimal agar mampu memecahkan masalah dengan baik. Pembelajaran blended learning memberikan banyak kegiatan pembelajaran matematika mandiri dan kolaboratif yang berdampak positif terhadap pencapaian hasil belajar.
Estudo das forças provocadas por ondas oceânicas em estruturas cilíndricas esbeltas offshore pela teoria linear de Airy
Authors: Montes Roger Otávio Pires , Da Silva Frederico Martins Alves , Pedroso Lineu José
Published: February 2024

Diante da crescente demanda energética, é significativo o aumento da utilização de estruturas offshore, como por exemplo, as plataformas petrolíferas e aerogeradores. Estas estruturas têm em comum o aspecto de estarem submetidas a carregamentos oriundos da ação de ondas oceânicas, e despertando cada vez mais o interesse de pesquisadores das áreas da engenharia civil, mecânica, naval e petrolífera. Portanto, compreender os fenômenos da interação fluido-estrutura e avaliar de maneira correta as forças provocadas pela ação de ondas nestas estruturas é fundamental para a execução de projetos seguros e econômicos. Por meio da observação da superfície do mar, nota-se vários conjuntos de cristas e vales, que se movimentam de forma aleatória e aparentemente, sem uma definição clara. Diante deste fato, é que surgem teorias que buscam identificar algum padrão do fenômeno e descrever como ocorre tais movimentos. Neste trabalho será avaliado uma estrutura offshore cilíndrica (monopile) submetida a ação de ondas oceânicas a partir da teoria linear de Airy para ondas de pequenas amplitudes. A partir da formulação matemática desta teoria, serão analisadas as forças e os momentos gerados por este tipo de carregamento, de grande importância para o desenvolvimento de bons projetos estruturais na área offshore.
The Application of Digital Technology in Tesla Automobile Industry: Key Factors and Global Market Expansion
Authors: Zhang Hengfei
Published: February 2024

This study aims to explore Tesla’s success factors and its key moves in its global market expansion. Tesla is unique because it is not just a car manufacturer but a software-driven technology company. This article first introduces Tesla’s application in a single operating system, integrating all software into a logical system to improve vehicle operating efficiency and user experience. Secondly, this study discusses Tesla’s Supercharger network and how this network can provide users with convenient charging solutions to promote the popularity of electric vehicles. Next, this article explores Tesla’s strategy of building a factory in China and how this move helps Tesla maintain a competitive advantage in the global market. Finally, this article highlights Tesla’s closed loop of hardware and software and how it continuously improves the performance and functionality of the car through continuous iterations of software. The findings of this study will help understand Tesla’s business model and success and provide useful inspiration for other companies in the increasingly competitive electric vehicle market.
Research on LVMH Valuation Report
Authors: Wang Yilin
Published: February 2024

LVMH is currently the world's largest luxury goods conglomerate. The company has established five mature luxury business lines in fashion and leather goods, wines and spirits, perfumes and cosmetics, watches and jewelry, and specialty retail. In 2022, total operating profit increased by 23% to 21 billion euros, with an operating profit margin of 26% and a net profit of 14 billion euros. The purpose of this valuation is to better facilitate the company's development, formulate corporate strategies, and make decisions regarding the direction of the company. This report serves as a reference for the Board of Directors of the client and analyzes the current equity value of LVMH.
Analysis And Research on The Influence of The Social Network on Public Opinion and The Transmission Path of The Epidemic
Authors: Jiang Fangni , Liu Junchen , Wang Hening , Xu Haolin
Published: February 2024

Social networks, a connection of social interactions and personal relationships by nodes, are becoming a vital part of the 21st century. Nearly all human beings have sorts of connections with social network, including but not limiting to personal relationships, electronic gadgets, as well as social media. However, human beings never thought about how important this social network has been to us. As an unprecedented COVID-19 wave hit the world in 2020, the roles of social networks never fail to elicit topics and highlights. Some claim that the social network creates negative impacts such as agony and rumors while others claim that it benefits our lives more than we actually thought. In this paper, my group and I investigate the relationship of social network and how it helps us to understand the COVID-19. To this end, we’ve gathered data and graphs showing the effect of COVID-19 and how social network mitigates the problem. Our findings indicate that social network brings both positive and negative impacts to our understanding of COVID-19. On the other hand, it helps us to understand the problem more, as well as the alleviation of such hazards. What’s more, for different groups, classifying as different age groups as well as different job groups, social network has a variety of impacts on them either.
Walmart's Business Strategy and Financial Analysis Based on Porter's Five Forces Analysis Model and SWOT
Authors: Miao Huaiyu
Published: February 2024

As one of the world's largest retailers, Walmart holds a crucial position in the retail industry. This article conducts an analysis of Walmart's operational performance to gain an in-depth understanding of its competitive position in the global retail market and identify potential growth opportunities and challenges. Focusing on industry analysis, company strategy, and comprehensive financial performance analysis of Walmart, the study employs SWOT analysis, value chain analysis, and Porter's Five Forces model to dissect Walmart's strategic and asset composition changes, shedding light on its profitability. While Walmart has consistently experienced revenue growth, it faces challenges in maintaining profitability. The debt-to-equity ratio displays a positive trend, indicating a balanced capital structure. However, the liquidity ratio has slightly decreased, warranting attention. The article recommends optimizing inventory management, strengthening digital marketing efforts, and prudently managing long-term debt to enhance Walmart's financial performance and competitive advantage. This article conducts a study of Walmart's operational performance within the retail industry, aiming to provide insights and support for investors and decision-makers in making strategic choices.
Relationship Between Gut Microbiota and Depression and Possible Treatment
Authors: Zhang Shenglan
Published: February 2024

As an increasingly prevalent mental disorder around the globe, depression influences more than 300 million people and attract attention of researchers to find out a clear and reliable mechanism. One of the largest influencers in the human body, gastrointestinal microbiota has raised the attention of researchers and serve as a clue to explain the onset of depression. The evidence from previous studies is summarized to support that the difference of gut microbiota does correlate significantly with the development of depression. Supported by the result of a variety of studies including animal study and human prospective studies, microbiome-gut-brain axis (MGBA) and more specific mechanisms such as the function of multiple microbial components are explained. Other factors that influence the abundance of gut microbiota such as fiber and nutrients are considered. Hence, possible dietary patterns with high fiber consumption, low fat, sufficient polyunsaturated fatty acid (PUFA), docosahexaenoic acid (DHA), tryptophan, glutamic acid, are suggested as possible treatment or prevention of depression.
Application of E-commerce Platform in Dry Bulk Shipping: Supply Chain Perspective
Authors: Zhang Zihe
Published: February 2024

With the increasing popularity of e-commerce platforms, integrating supply chain and e-commerce has become an important research topic. As a key component of supply chain logistics, dry bulk shipping has also begun to transform towards e-commerce platforms. However, the transformation resistance is relatively high due to the traditional ship-owner and cargo-owner transaction model. In response, some dry bulk shipping companies have started exploring the potential of e-commerce platform applications. This paper aims to provide an overview of the current situation and analyze the prospects of e-commerce platform integration in the dry bulk shipping industry from a supply chain perspective. The study will examine the benefits and challenges of e-commerce platform adoption in dry bulk shipping, the impact of platform integration on supply chain efficiency, and the potential implications for future industry development.
Research on stray animal tort liability
Authors: Luo Shiqi , Sun Zhouhao
Published: February 2024

With the increase of the total number of pets, abandoned pets have become more and more common, and gradually exposed the existing problems of stray animals in our country. This paper will discuss the concept of stray animal tort liability, the current situation of stray animals, the reference of excellent systems outside the region and the measures to improve stray animal tort liability in the four aspects of our country's stray animal tort liability, and explore a reasonable and scientific governance system combined with our country's actual situation, so as to truly protect the legitimate rights and interests of those infringed by stray animals.
Effects of Different Types of Intermittent Fasting on Obesity, Inflammation, and T2DM
Authors: Zheng Youyi
Published: February 2024

Currently, there is much discussion on how to deal with the increasing trend of becoming overweight and the chronic diseases it is associated with. Obesity and its associated chronic diseases are a big concern in modern living. It has been discovered that intermittent fasting, may be a practical solution to this problem. As this potential solution has yielded positive results for patients who have been enrolled in obesity medical studies. This paper principal goal will be to collect and analyzed the research data related to type 2 diabetes (T2DM), obesity and intermittent fasting, and explore whether intermittent diet has a positive impact on the cure of obesity and related diseases. Research has found that various intermittent diets have a positive impact on weight control, especially the ADF diet. Although participants may experience some adverse reactions during intermittent eating, the impact is not significant, and the vast majority of participants can persist until the end of the experiment and achieve good results. Although intermittent diet has no significant effect on the intervention of inflammation, its intervention on type 2 diabetes, is effective and long-lasting. Overall, intermittent fasting is more effective in intervening and treating obesity and related chronic diseases compared to traditional therapies and may have a more widespread promotion in the future.
Microsoft’s Evolution in Digital Era: A Financial Analysis and Porter’s Model
Authors: Liu Yiqi
Published: February 2024

The world in 2023 is unlike the one in 2019. As the supply chain is expended due to the highest inflation since 1984, and the Russo-Ukrainian conflict is prolonged, the software market is seeing increased rivalry and concerns about the impact of digital transformation. The purpose of this case study is to evaluate the recent performance, identify potential risks, and discuss strategic adjustments that Microsoft may take. By examining key financial metrics from 2019 to 2023, and using common-size analysis, this study analysed the profitability, liquidity, and overall health of Microsoft’s financial structure. Through Porter’s five force model, this study helps understand the company’s competitive force and growth potential. Moreover, this study summarizes and highlights concerns and vulnerabilities within Microsoft. This is essential for developing long-term strategies for both investors and managers. It was discovered that Microsoft has shown weaker performance since 2019, yet it has managed to maintain its dominant position in the software industry by emphasizing cloud-based solutions and artificial intelligence.
Branding in the Digital Age: How Influencers Marketing and Authenticity Reshape Brand Perceptions
Authors: Zhou Yuying
Published: February 2024

The digital landscape's evolution has catalyzed the rise of influencer marketing as a potent force, fundamentally reshaping brand perceptions and embarking on a comprehensive exploration of this phenomenon. This paper underscores brands' multifaceted objectives in the influencer marketing field, encompassing efforts to magnify brand visibility, precision-target niche audiences, and bolster sales conversions. The literature review session highlights the increasing pivot from traditional media outlets to dynamic social media platforms, each offering unique advantages and engagement nuances. At the core of this discourse is the indispensable attribute of authenticity, whose role is in establishing trust, credibility, and deeper connections in the influencer space. To illustrate these dynamics in tangible settings, the research ventures into case analyses of brands like Glossier and AG1, capturing the essence of effective influencer collaborations. Conversely, the Snap Spectacles-Luka Sabbat partnership is a cautionary tale, spotlighting the pitfalls when authenticity falters. Ultimately, the paper presents meticulous recommendations tailored for brands and influencers, guiding them towards a refined, impactful influencer marketing trajectory.
Research on the Promotion of Brand Value of Commercial Sports Brands Based on Marketing System -Take Under Armour as an Example
Authors: Zhang Jiayi
Published: February 2024

The brand is the most valuable intangible asset of enterprises, and a prestigious brand will win a broader space for development. With the development of society, enterprises pay more and more attention to the influence of brand value, strengthen the construction of soft power, and seek a variety of ways or professional institutions to value, add value, and endorse the brand. In the field of sports, sports brands have become an essential condition and driving force for the development of the cultural industry. In the case that the public's pursuit of sports brands has become an average psychological demand, the premium role of brands has become increasingly apparent. How to enhance brand value has become an essential topic of enterprise publicity work exploration and research. The article will take the Under Armour brand as an example through the analysis of the current sports business brand in the market, Under Armour brand, product, marketing strategy, market positioning, and data analysis of five levels, and put forward how to strengthen the brand concept, strengthen brand awareness, firmly grasp the consumer market and other methods to enhance Under Armour brand value.
Enhancing Grid Stability and Sustainability: Integrating Lithium-Ion Batteries with Solar Energy for Large-Scale Applications
Authors: Guo Kaiwang , Wang Lingfu , Zeng Tianrui
Published: February 2024

Solar energy serves as a pollution-free, environmentally friendly energy source and a way to achieve sustainable energy. Nonetheless, the variability of solar energy caused by daily and seasonal changes in sunlight availability may cause an imbalance between energy supply and demand. This passage discussed the limitations of solar energy and problems with large-scale grids combined with solar energy and lithium-ion batteries, and their corresponding solutions, mentioning cost issues and the key point that may need extra attention to achieve an ideal status for a grid energy storage system. To address this issue, this paper presents a detailed analysis and discussion on Lithium-ion batteries and the synergy between lithium-ion batteries and solar power. In order to apply this combination in large-scale grids, high energy requirements can be achieved by changing the anode material from graphite to silicon, but this will inevitably lead to an increase in cost. This paper also discusses high-efficiency power networks and compares them to lithium-metal batteries (e.g., LOBs and LSBs). Solving this problem could work towards reducing CO2 emissions and provide energy to achieve a balance between energy supply and demand, and could also be used to provide emergency power.
Postmodern Representations and Reflections in Hong Kong Urban Cinema: A Study on the Works of Heiward Mak Hei-Yan
Authors: Yang Xinrui
Published: February 2024

In the new millennium, a discontinuity of postmodern elements began to surface in Hong Kong commercial films. However, young director Heiward Mak Hei-yan integrated postmodern elements into her works, which are primarily urban films, inheriting and developing the postmodern tradition of Hong Kong cinema. She does this primarily by shaping marginal urban landscapes and crowds, capturing the less noticed aspects of Hong Kong city, and demonstrating the anti-grand narrative characteristic of postmodernism. By establishing a postmodern perspective on love, she breaks and "rebels" against traditional romance films, not just merely glorifying the myth of love, but emphasizing the questioning of the eternal view of modern love. Simultaneously, she illustrates the dilemmas of postmodern alienation to portray the contemporary postmodern mentality and cultural symptoms of Hong Kong people in this unique geographical location. Her urban films reflect her positive thinking about urban romance, life, and mental state in a postmodern context, providing the possibility of parallelism between commerciality and postmodernism, and offering insights for the development of Hong Kong cinema.
Diets of Vegetarians and Meat-Eaters Affect the Health Problems They Suffer
Authors: Hong Jiahui
Published: February 2024

As society evolves, dietary choices have expanded significantly, offering a wealth of options beyond traditional limitations. One noticeable trend is the rising number of non-religious vegans, who are embracing plant-based diets due to their myriad health benefits when balanced correctly, mitigating some issues seen with conventional vegetarian diets. Conversely, the surge in meat production has led to an increasing number of carnivores, with some individuals even adopting exclusively meat-based diets. This article aims to explore the dietary disparities between vegetarians and meat eaters and the potential health concerns associated with each. Dietary habits play a pivotal role in shaping health. Vegetarians often grapple with protein and iron deficiencies due to their exclusion of meat, leading to potential clotting disorders and symptoms such as mental depression and fatigue. In contrast, meat eaters generally have an ample protein supply, but excessive consumption of red and processed meats has been linked to diseases like cancer. Furthermore, vegetarians may sometimes overlook essential nutrients found in meat, such as heme iron. This nutrient can be absorbed more easily than non-heme iron in plant, which may cause deficiency anemia. On the flip side, meat-heavy diets may lack essential aspects. A diet devoid of fruits and vegetables typically results in insufficient dietary fiber intake, giving rise to various health problems. Both dietary patterns have their merits and demerits, individuals must adjust their diets to address these shortcomings.