bluuebunny/crossref_metadata_2025 huggingface dataset:
Perceived stress, self-esteem, and experiences of discrimination: Examining predictors of depression within integrated behavioral health
Authors: Cooper Zach , Pitner Ronald
Published: April 2024

Background: Depression is pervasive and influences health. Individuals with depression frequently present to primary care providers, and integrated care models have emerged to better address depression within primary care settings. Though there has been increased understanding regarding methods of addressing depression in primary care through integrated care models, there is a lack of understanding regarding the nuanced way racial discrimination influences depression within these settings.
Method: Our study evaluated the nuanced presentation of depression within an integrated care setting examining the role of racial discrimination and the experience of depression. Stratified random sampling was used, yielding 383 participants (228 White and 155 Black). Participants completed a survey designed to assess levels of anxiety, depression, perceived stress, self-esteem, experiences with discrimination, and demographic information. A series of t-tests were run to analyze differences between racial groups regarding depression, anxiety, stress, self-esteem, and discrimination. Then a hierarchical regression model was utilized to assess which factors predicted variance in depression.
Result: Our findings indicated that anxiety, perceived stress, and experiences with discrimination were strong predictors of depression (F (4, 221) = 91.75, p < 0.001) and accounted for 63% of the variance in depression.
Conclusion: Integrated care models innovate primary care settings by expanding medical teams to address mental health needs. Our paper identifies additional patient concerns within these settings including stress, discrimination and self esteem while identifying methods integrated care models can screen for and address these concerns as a routine component of care.
Construction and Characterization of Recombinant Vectored Vaccines for Rabies Virus
Authors: Khalifa Manar E. , Munir Muhammad
Published: April 2024

Recombinant vectored vaccines offer trailer-made immunization strategies and are economical, quick to engineer and demand less laboratory infrastructures. Here we describe a detailed protocol for genetic manipulation of vesicular stomatitis virus (VSV) vector system encoding the antigenomic sense RNA of VSV by replacing VSV glycoprotein (VSV-G) with modular rabies virus glycoprotein (RV-G) gene. The production of replication competent recombinant VSV (rVSV) involves the transient transfection of BHK-21 cells with pVSV-expressing RV-G backbone along with transcriptional initiating helper plasmids under the control of T7 polymerase. In addition, we provide comprehensive guidelines on functional, molecular, and structural characterization of the recombinant rVSV-based rabies vaccine.
DIAGNOSIS OF INTERNAL ROOT RESORPTION: CLINICAL MANIFESTATIONS AND RADIOLOGICAL FEATURES
Authors: Gadzhula Nataliia , Povsheniuk Anastasiia , Cherepakha Olena
Published: April 2024

Introduction. There are several types of internal tooth resorption, each of which has its own etiology, pathogenesis, clinical signs and radiological features. Each type of resorption can have serious consequences for the tooth and surrounding tissues, so it requires timely and accurate diagnosis, specific treatment strategies, observation and monitoring. The study aimed to represent the clinical manifestations and diagnostic peculiarities of internal root resorption, enabling practicing dentists to timely diagnose lesions and take appropriate measures to avoid further complications.
Methods. Patients with internal inflammatory root resorption (n=8) and with internal replacement resorption (n=7) were included in the study. The groups were analyzed according to clinical and radiological parameters. Pulp vitality was determined by standard examination methods (inspection, probing, percussion, sensitivity test, EOD). When evaluating X-ray images, the size, localization and contours of the resorption of hard tooth tissues and/or bone destruction, periapex, the quality of filling the root canals were considered.
Results. Affected teeth with partially vital pulp have caused symptoms and/or signs of acute or chronic pulpitis. Internal inflammatory and internal replacement types of resorption in depulped teeth had similar clinical signs: asymptomatic course, tooth color change; lesions of resorption were detected accidentally during radiographic examination. The majority of the teeth with internal root resorption did not have prior endodontic treatment (86.7%) and had a normal periapex (60.0%). In 14.3% of cases with internal replacement resorption some ankylosis with reduced mobility was revealed. Most of the affected teeth were anteriors (53.3%), internal resorption lesions were mainly located in the middle (50.0%) and the lower thirds of the root (37.5%). Radiographically, in inflammatory resorption a symmetric oval-shaped radiolucent enlargement of the root canal with smooth and well-demarcated margins was found; in case of replacement resorption, a round-shaped (ballooning) radiolucency enlargement with an irregularly (cloudy) and/or mottled inclusions of bone-like tissue was detected.
Conclusions. Early diagnosis, elimination of the cause, timely management of root resorption are mandatory for tooth preservation. The main method of diagnosis of internal tooth resorption is radiographic, as the process can proceed without subjective painful sensations. The leading role belongs to dental computer tomography. One of the radiological criteria of pathological tooth resorption is a change in the internal configuration of the root canal.
A REVIEW ON MOLECULAR DOCKING AND ITS APPLICATION
Authors:   School of Pharmaceutical Sciences, Shri Guru Ram Rai University., Chaudhary M. , Tyagi K. ,   Patel Nagar, Uttarakhand, Dehradun-248001, India.
Published: April 2024

Molecular Docking is powerful computer strategy, critical in drug development, structural biology, and biomolecular interaction researchproviding a thorough grasp of its importance in modern scientific study. Molecular docking involves forecasting how a small molecule, often a potential medication, will interact with a target biomolecule like DNA or a protein. This process examines the spatial and energetic compatibility of the ligand with the active site of the receptor, assisting in the discovery of new drug candidates, refining existing compounds, and understanding the intricate interactions between drugs and receptors. Molecular Docking a computational tool that evaluates and ranks different ligand-receptor conformations based on their binding energies. An accurate scoring function is imperative for distinguishing high-affinity ligands from low-affinity ones, this makes it possible to identify potential medication candidates for validation in experiments. Molecular docking finds application in various domains of Drug Progress, comprisingstructure-based medication development, virtual screening,lead optimization.When creating a medicine based on structure, the target biomolecules three-dimensional structure is employed to guide the ligand selection that will communicate with the region that is active. Virtual examination accelerates the discovery of potential drug properties by rapidly evaluating large compound libraries. Lead optimization, on the other hand, is facilitated through iterative docking studies aimed at enhancing binding affinity and pharmacological properties. The field of molecular docking has seen a proliferation of diverse techniques designed to address the unique challenges of structure-based drug design and biomolecular interaction analysis. This report provides an in-depth examination of thedistinct methodologies of docking, its principles, applications, and their importance in advancing our understanding of molecular interactions in different contexts.The diversity of docking methods arises from the need to accommodate different types of molecules, target structures, and research objectives.
Evaluation of the productivity potential of eggplant lines developed on the basis of interspecific hybridisation and gametic breeding
Authors: Kondratenko S. I. , Samovol O. P. , Serhiienko O. V. , Tkalych Yu. V. , Marusyak A. O.
Published: April 2024

Purpose. Improvement of the gene pool of the cultivated form of eggplant (Solanum melongena L.) through interspecific hybridisation with Solanum aethiopicum L. and gametic breeding; analysis of the interspecific lines for a set of valuable quantitative traits determining the yield structure. Methods. Studies for the comprehensive evaluation of eggplant lines of interspecific origin were carried out during 2021-2023 in protected soil conditions at the experimental base of the Institute for Vegetable and Melon Growing of the National Academy of Agrarian Sciences. Phenological observations and biometric measurements of plants of four lines were carried out. The stability of the manifestation of seven quantitative traits during the research years was determined by the methods of variation statistics (calculation of the mean square deviation (σ), coefficient of variation (V), Pearson's paired linear correlation (rp)). Results. The analysis identified eggplant lines of interspecific origin that were superior to the standard variety 'Almaz' in terms of the level and stability of quantitative traits. Thus, F6(Pavlotas-20/var. 'Almaz')I1 and ВС1[F5 (Pavlotas-20/var. 'Almaz')]I1 showed a statistically significant increase in fruit width (by 16.48% and 14.85%, respectively). Meanwhile, line BC2 [F5 (Pavlotas-20/var. 'Almaz')]I1 exhibited higher productivity (by 18.11%) compared to the standard variety. The correlation analysis shows that the trait “Productivity of one plant” has a strong positive relationship with the trait “Number of fruits per plant” (rp = 0.75) and a strong negative relationship with “Average fruit width” (rp = -0.70) and “Duration of the period from mass germination to technical fruit maturity” (rp = -0.72). The selected line BC2[F5(Pavlotas-20 / var. 'Almaz')]I1 exhibited a four-day shorter period from mass germination to technical fruit maturity compared to the standard variety. Conclusions. The line BC2[F5(Pavlotas-20 / var. ' Almaz ')]I1was isolated based on the complex of quantitative traits. It underwent an additional stage of gametophytic breeding, resulting in a high adaptive potential to growing conditions.
Selection evaluation of new self­pollinated sunflower (Helianthus annuus L.) lines with resistance to sulfonylurea herbicides and downy mildew [Plasmopara halstedii (Farl.) Berl. et. de Tony]
Authors: Ilchenko A. S. , Varenyk B. F. , Karapira S. I.
Published: April 2024

Purpose. To determine the breeding value of a new sunflower source with complex resistance to sulfonylurea herbicides and downy mildew. Methods. In the research process, field (hybridization, line testing, individual selection, line evaluation), visual (phenological observations), laboratory (immunological evaluation of resistance to DM), vegetation (evaluation of resistance to herbicides) and mathematical and statistical (processing of experimental data and determination of reliability of research results) methods were used. Results. During 2020–2023, new self­pollinated sunflower lines were studied in the cross­pollination and bree­ding department of the Plant Breeding & Genetics Institute – National Center of Seeds and Cultivar Investigation (PBGI – NCSCI). Based on the results of the work, 33 self­pollinated sunflower lines with complex resistance to sulfonylurea herbicides and downy mildew (DM) were created and evaluated. The lines were created using domestic breeding populations that were able to reach their full genetic potential in various conditions. These populations were adapted to cultivation in the southern steppe of Ukraine and were resistant to a complex of diseases and pests. Additionally, they had increased seed yield and plasticity. The new source material obtained is constant, stably productive lines used in the subsequent breeding programme. According to the results of the trials, almost all the hybrids obtained (F1) showed a yield of more than 1.0 t/ha. Lines with the highest level of combining ability in terms of yield (heterozygous hybrid progeny with increased viability for the main economic and valuable traits) will be selected for further research and will be involved in the creation of new hybrids resistant to sulfonylurea herbicides and DM. Conclusions. Research showed that traits such as sulfonylurea herbicide resistance and downy mildew resistance can be combined in one line. Herbicide resistance in sunflowers is easy to control in the field, while downy mildew resistance needs to be controlled in the laboratory.
Yield and quality of winter wheat grain under different cultivation technologies
Authors: Zaima O. A. , Derhachov O. L. , Siroshtan A. A. , Pravdziva I. V. , Khomenko T. M.
Published: April 2024

Purpose. Study of the influence of preceding crops and sowing terms on the yield and quality of winter wheat grain. Methods. The study analyzed 11 varieties of soft winter wheat, ‘Podolianka’, ‘MIP Yuvileina’, ‘MIP Fortuna’, ‘MIP Roksolana’, ‘MIP Feieriia’, ‘MIP Vidznaka’, ‘MIP Nika’, ‘MIP Darunok’, ‘MIP Aelita’, ‘MIP Aurika’ and ‘MIP Dovira’. The study investigated the impact of preceding crops (soybean, sunflower, corn/MWR, green manure (white mustard), and mustard/seed) and sowing dates (25 September, 5 and 15 October) on grain yield and baking quality. Results. The research was conducted in 2021–2023 on the experimental fields of the V. M. Remeslo Myronivka Institute of Wheat. The weather conditions were characterized by high tempe­ratures and uneven precipitation. The highest winter wheat yields were obtained after green manure as a preceding crop (7.29 t/ha), and the lowest yields after sunflower (5.35 t/ha). Shifting the sowing date from 25 September to 15 October reduced the average yield of the varieties. The only exception to the results were those obtained after crops such as sunflower and mustard when sown on 5th October, which yielded 5.54 and 6.51 t/ha respectively. The highest yields (6.39–6.95 t/ha) were observed for the varieties ‘MIP Darunok’, ‘MIP Aurika’, ‘MIP Aelita’ and ‘MIP Vidznaka’. Higher protein, gluten and sedimentation values were observed after green manure and soya as a preceding crop; in addition, after soya there was a tendency to increase flour strength and bread volume. The aforementioned shift in sowing date also resulted in a decrease in bread volume and an increase in vitreousness; the remaining parameters were within the range of significant differences. The varieties ‘MIP Dovira’, ‘MIP Nika’ and ‘MIP Roksolana’ were characterized by the highest protein content in the grain. According to the complex of quality indicators, ‘MIP Yuvileina’, ‘MIP Roksolana’ and ‘MIP Aurika’ prevailed over others. Conclusions. It was found that green manure and soybean as a preceding crop, as well as optimal sowing dates – the third decade of September and the first of October – provided the maximum yield of the varieties studied. The varieties with the hig­hest yields were ‘MIP Darunok’, ‘MIP Vidznaka’, ‘MIP Aurika’ and ‘MIP Aelita’. According to the complex of grain quality indicators, the varieties ‘MIP Yuvileina’, ‘MIP Roksolana’ and ‘MIP Aurika’ were distinguished.
SERVICE IN LOCAL GOVERNMENT UNDER MARTIAL LAW
Authors: Bozhko Volodymyr M.
Published: April 2024

The article examines certain aspects of legal regulation of service in local self-government bodies introduced under martial law in Ukraine. To counteract

the military aggression of the russian federation, martial law was introduced in Ukraine, general mobilization was announced, and several special rules for civil service and service in local self-government bodies were introduced. These innovations are extremely important because in peacetime, because of the decentralization reform in Ukraine, local governments have acquired many additional powers and funds, which allowed them to form a kind of municipal front in the face of armed aggression, providing a reliable shoulder to the state in the fight against the aggressor.

The article substantiates why the Law of Ukraine «On the Organisation of Labour Relations under Martial Law» № 2136-IX of 15 March 2022 extended its effect to local self-government officials only from 19 July 2022.

The article examines the content of the following peculiarities of service in local self-government bodies introduced under martial law: 1) the possibility of establishing probationary periods when concluding an employment contract for any category of local self-government officials has been introduced; 2) the procedure for transferring and changing the essential working conditions of local self-government officials was significantly simplified; 3) expanded the powers of the employer to establish and record working hours and rest periods of local self-government officials; 4) restrictions were introduced on the application of a number of labour law provisions aimed at exercising the right of local self-government officials to rest; 5) new conditions for the remuneration of local self-government officials were introduced; 6) it is allowed to suspend certain provisions of a collective agreement at the initiative of the employer; 7) special rules on suspension of an employment contract were introduced.

The article concludes that the peculiarities of service in local self-government bodies introduced under martial law were not self-sufficient. They are aimed at assisting local self-government bodies in exercising their powers in such a tragic period of national history. Therefore, only in time will it be possible to conclude how effective they were. For now, we can only state that the legislator has significantly changed the balance of interests of the parties to the local self-government service relationship in favour of the employer to help protect the public interest.
Artificial Intelligence Approaches in Healthcare Informatics Toward Advanced Computation and Analysis
Authors: Priyanka E.B. , Thangavel S. , Mohanasundaram R , Subramaniam Shamala
Published: April 2024

Introduction

Automated Machine Learning or AutoML is a set of approaches and processes to make machine learning accessible for non-experts. AutoML can exhibit optimized enhancement of an existing model or suggest the best models for precise datasets. In the field of computerized Artificial Intelligence (AI), medical experts better utilize AI models with available encrypted information science ability.

Methods

This paper aims to characterize and summarize the stage-wise design of Automated Machine Learning (AutoML) analysis e-healthcare platform starting from the sensing layer and transmission to the cloud using IoT (Internet of Things). To support the AutoML concept, the Auto Weka2.0 package, which serves as the open-source software platform, holds the predominant priority for experimental analysis to generate statistical reports.

Results

To validate the entire framework, a case study on Glaucoma diagnosis using the AutoML concept is carried out, and its identification of best-fit model configuration rates is also presented. The Auto-ML built-in model possesses a higher influence factor to generate population-level statistics from the available individual patient histories.

Conclusion

Further, AutoML is integrated with the Closed-loop Healthcare Feature Store (CHFS) to support data analysts with an automated end-to-end ML pipeline to help clinical experts provide better medical examination through automated mode.
Symptoms, Consequences, and Action Across of Methadone Poisoning in Children Referred to a Hospital in the South of Iran
Authors: Fariabi Reza , Raesi Rasoul , Sardu Ehsan Goroei , kermani Bahareh , Movahed Ehsan , Salarpour Ali , Daneshi Salman
Published: April 2024

Introduction

The aim of this study is to investigate the consequences of children with methadone poisoning referred to the emergency department of Imam Khomeini Hospital in Jiroft in 2020. Methadone poisoning in children is one of the major public health problems and one of the most common causes of emergency room visits.

Methods

This research is a case series study. The study population included all children under 15 years old. Data were collected through interviews with the child's parents or companions, as well as a medical examination of poisoned children in the hospital, and by reviewing the records of past patients and recorded in the data registration form. Data were analyzed using SPSS software version 21.

Results

Of the 90 children surveyed, 66.7% were in the age range of 2 months to 3 years, the mean age of the children was 2.49 ± 0.89 years old, and 51.1% of patients with poisoning in the morning and autumn were the highest number of patients. Education level of parents, 50% of men and 38% of women were illiterate. 76.7% had taken 1 to 5 mg of methadone. The most common side effect of methadone poisoning was vomiting (41.1%).

Conclusion

Incidental use of methadone in children is very high so that families and surroundings, doctors, and health personnel have sufficient knowledge of the most dangerous complications of methadone and proper maintenance, keeping this dangerous substance from the reach of children should be trained to parents.
La escritura académica en la enseñanza de la ciencia política: Una revisión del caso argentino
Authors: Rinaldi Sebastian
Published: April 2024

En este trabajo se analiza la relevancia de la escritura académica en carreras de grado de ciencia política en Argentina, un tema escasamente abordado entre los estudios sobre alfabetización universitaria en el país y la región, aunque inscrito en la tradición de estudios curriculares disciplinares. Para tal fin, y desde un enfoque cualitativo centrado en el análisis documental, se examinan los programas vigentes de cursos correspondientes a seis universidades del Área Metropolitana de Buenos Aires, territorio que contiene la mayor concentración de carreras de grado en el país. En el análisis se consideran cuatro ejes fundamentales: a) el currículo como contexto para el desarrollo de la escritura académica, b) el lugar de la escritura en los objetivos de los cursos, c) la determinación curricular y selección de lecturas y d) la producción escrita en las modalidades de enseñanza y evaluación. Como conclusión, se advierte la insuficiente diversidad de textos que los estudiantes aprenden a elaborar, predominando una enseñanza academicista que atenta contra la formación crítica y científica.
Retórica y discurso político como función argumentativa de la verdad en Aristóteles y Platón: Claves desde la oratoria griega
Authors: Álvarez-Galeano Manuel , Sarmiento-Moscoso Diana , Curay-Banegas Edgar , Álvarez-Galeano Luis
Published: April 2024

Se presenta un estudio que tiene como objetivo analizar la convergencia entre la retórica y el discurso político en la búsqueda argumentativa de la verdad, desde las perspectivas de Platón y Aristóteles, esbozando una comparación crítica de sus enfoques y su impacto en la construcción de la elocuencia y la persuasión, partiendo del contexto político de la antigua Grecia. El estudio emplea una metodología basada en la investigación cualitativa que busca proporcionar una descripción integral de las variables bajo un examen desde la mirada paralela; este enfoque implica un análisis bibliográfico, descriptivo y reflexivo, que utiliza fuentes de investigación de manera sistemática. Asimismo, se opta por un método inductivo-deductivo. En cuanto a la selección de fuentes, se escogieron 50 documentos relacionados con el tema, seleccionados según su relevancia, confiabilidad, actualidad, objetividad y claridad, en función de la oratoria y las obras la Poética, la Retórica y el Gorgias. De estos, se utilizaron 27 publicaciones para el trabajo. Estas fuentes fueron sometidas a varios análisis, incluyendo la textometría comparativa de la lingüística del discurso, así como consideraciones de ecología del lenguaje en función del contexto histórico y social en el que se desarrollaron las obras de Aristóteles y Platón. Se concluye que la retórica se puede utilizar para una variedad de propósitos, siempre que se haga desde una coordenada epistémica de la verdad de manera articulada con la argumentación; además, se puede evidenciar cómo los principios de la oratoria griega tienen orientaciones que se mantienen vigentes, planteando una cercanía interdisciplinaria con las humanidades y los estudios políticos.
Evaluación 360 grados y su efecto, análisis comparativo pre y post pandemia Covid -19 en una clínica privada, Distrito Metropolitano de Quito - Ecuador
Authors: Hidalgo Yerovi Victoria
Published: April 2024

El presente estudio se llevó a cabo en una clínica privada en Quito con el propósito de identificar los factores que causaron un cambio en la actitud de los colaboradores, generando situaciones críticas que afectan el ambiente laboral. Por este motivo, el objetivo general se centró en realizar un análisis descriptivo comparativo a través de la aplicación de un modelo de evaluación 360 grados. Para este estudio de caso se desarrolló una metodología mixta comparativa basada en la evaluación de diez variables directamente relacionadas con los colaboradores y su entorno laboral. Se compararon los resultados del mismo modelo aplicado en el año 2019 versus el año 2022. Con el objetivo de llevar a cabo un proceso eficiente, se procedió a evaluar las trece unidades jerárquicas presentes en la clínica dando un total de 92 colaboradores. Los resultados arrojaron que las variables más afectadas fueron las siguientes: la motivación disminuyó en 1.08 puntos, la satisfacción laboral en 0.97 puntos, la capacidad personal en 0.88 puntos, el liderazgo en 0.71 puntos, y la actitud y colaboración en 0.69 puntos. Es esencial tener en cuenta que, a nivel mundial, los entornos laborales más vulnerables durante la pandemia y confinamiento fueron los hospitales, clínicas, unidades de emergencia, paramédicos y centros de salud. Concluyendo, es fundamental realizar una evaluación del entorno laboral, con el propósito de identificar las mejoras necesarias. Esto garantizará la preservación de ambientes laborales saludables y empleados satisfechos y comprometidos.
Projected Time for the Elimination of Cervical Cancer Under Various Intervention Scenarios: Age-Period-Cohort Macrosimulation Study
Authors: Chen Yi-Chu , Chen Yun-Yuan , Su Shih-Yung , Jhuang Jing-Rong , Chiang Chun-Ju , Yang Ya-Wen , Lin Li-Ju , Wu Chao-Chun , Lee Wen-Chung
Published: April 2024

Background

The World Health Organization aims for the global elimination of cervical cancer, necessitating modeling studies to forecast long-term outcomes.

Objective

This paper introduces a macrosimulation framework using age-period-cohort modeling and population attributable fractions to predict the timeline for eliminating cervical cancer in Taiwan.

Methods

Data for cervical cancer cases from 1997 to 2016 were obtained from the Taiwan Cancer Registry. Future incidence rates under the current approach and various intervention strategies, such as scaled-up screening (cytology based or human papillomavirus [HPV] based) and HPV vaccination, were projected.

Results

Our projections indicate that Taiwan could eliminate cervical cancer by 2050 with either 70% compliance in cytology-based or HPV-based screening or 90% HPV vaccination coverage. The years projected for elimination are 2047 and 2035 for cytology-based and HPV-based screening, respectively; 2050 for vaccination alone; and 2038 and 2033 for combined screening and vaccination approaches.

Conclusions

The age-period-cohort macrosimulation framework offers a valuable policy analysis tool for cervical cancer control. Our findings can inform strategies in other high-incidence countries, serving as a benchmark for global efforts to eliminate the disease.
Identifying Links Between Productivity and Biobehavioral Rhythms Modeled From Multimodal Sensor Streams: Exploratory Quantitative Study (Preprint)
Authors: Yan Runze , Liu Xinwen , Dutcher Janine M , Tumminia Michael J , Villalba Daniella , Cohen Sheldon , Creswell John D , Creswell Kasey , Mankoff Jennifer , Dey Anind K , Doryab Afsaneh
Published: April 2024

BACKGROUND

Biobehavioral rhythms are biological, behavioral, and psychosocial processes with repeating cycles. Abnormal rhythms have been linked to various health issues, such as sleep disorders, obesity, and depression.

OBJECTIVE

This study aims to identify links between productivity and biobehavioral rhythms modeled from passively collected mobile data streams.

METHODS

In this study, we used a multimodal mobile sensing data set consisting of data collected from smartphones and Fitbits worn by 188 college students over a continuous period of 16 weeks. The participants reported their self-evaluated daily productivity score (ranging from 0 to 4) during weeks 1, 6, and 15. To analyze the data, we modeled cyclic human behavior patterns based on multimodal mobile sensing data gathered during weeks 1, 6, 15, and the adjacent weeks. Our methodology resulted in the creation of a rhythm model for each sensor feature. Additionally, we developed a correlation-based approach to identify connections between rhythm stability and high or low productivity levels.

RESULTS

Differences exist in the biobehavioral rhythms of high- and low-productivity students, with those demonstrating greater rhythm stability also exhibiting higher productivity levels. Notably, a negative correlation (C=–0.16) was observed between productivity and the SE of the phase for the 24-hour period during week 1, with a higher SE indicative of lower rhythm stability.

CONCLUSIONS

Modeling biobehavioral rhythms has the potential to quantify and forecast productivity. The findings have implications for building novel cyber-human systems that align with human beings’ biobehavioral rhythms to improve health, well-being, and work performance.

CLINICALTRIAL
Measuring the Digital Skills in nursing degree students (Preprint)
Authors: Berenguer-Poblet Marta , Mora-Lopez Gerard , Reverte-Vilarroya Silvia , Fernandez Saez José , Reixach Espaulella Elisenda , Andres Reig Erik
Published: April 2024

BACKGROUND

In the healthcare field the digital revolution has changed the way in which healthcare is provided through the prevention, diagnosis and monitoring of people's health. In Catalonia, work has been conducted to evaluate the digital competence (DC) of healthcare professionals using a validated test based on the ACTIC (accreditation of competence in information and communication technologies) model. It is therefore important

OBJECTIVE

To determine the DC level of nursing students as future healthcare professionals.

METHODS

The aim of this study is to analyze the current DC level of students taking the Degree in Nursing at the Terres de l’Ebre Campus, Universitat Rovira i Virgili (URV), Catalonia, Spain. We have used a questionnaire to evaluate the DC level of these students.

RESULTS

Our sample comprised 147 students from various modules of the Degree in Nursing. Our results show differences in levels of self-perception and DC but also differences in the competence of students across the various academic years.

CONCLUSIONS

Evaluating the level of competence of nursing degree students is fundamental for practising and enhancing the most important digital competencies required in the field of professional nursing
Real-Time Delirium Prediction in Intensive Care Units: A Machine-Learning-Based Model Using Monitoring Data (Preprint)
Authors: Park Chan Min , Han Changho , Jang Su Kyeong , Kim Hyungjun , Kim Sora , Kang Byung Hee , Jung Kyoungwon , Yoon Dukyong
Published: April 2024

BACKGROUND

Delirium in intensive care units (ICUs) poses a significant challenge and affects not only global patient outcomes but also healthcare efficiency. The development of an accurate, real-time prediction model for delirium represents a crucial advancement in critical care and addresses the need for timely intervention and resource optimization in ICUs worldwide.

OBJECTIVE

This study aimed to create a novel machine-learning model for real-time delirium prediction in ICUs using the random forest method.

METHODS

Distinct from existing approaches, the model integrated routinely available clinical data such as age, sex, and patient monitoring device outputs to ensure its practicality and adaptability in diverse clinical settings. Using these data, we trained a random forest model to predict the occurrence of delirium in patients. Retrospective data were used for training and internal validation. Retrospective data were used for training and internal validation. Prospective data were used to confirm the reliability of the delirium determination. CAM-ICU records assessed by ICU nurses were collected and validated by qualified investigators performing CAM-ICU measurements prospectively on the same patients and then determining Cohen's kappa coefficient. In addition, we additionally verified the performance of the model using a temporal validation cohort and performed external validation using data from an external hospital.

RESULTS

The Kappa coefficient between labels generated by ICU nurses and prospectively verified by qualified researchers was 0.81. This indicates that the recorded CAM-ICU results were reliable. The model showed robust performance in internal validation (area under the receiver operating characteristic curve [AUROC]: 0.82, area under the precision–recall curve [AUPRC]: 0.62) and maintained its accuracy in temporal validation (AUROC: 0.73, AUPRC: 0.85), confirming its reliability over time. External validation across various patient populations and time frames further confirmed its effectiveness (AUROC: 0.84, AUPRC: 0.77).

CONCLUSIONS

Our model represents a significant breakthrough in the management of delirium in ICUs and offers a real-time, data-driven approach for improving patient care. The proven accuracy and adaptability of this model in various clinical scenarios underscore its potential to substantially improve patient outcomes and operational efficiency in ICUs. The integration of this model into current healthcare practices may lead to major advancements in early delirium detection and treatment, thereby reducing the ICU stay and improving the recovery rate.
Radiographic analysis of teeth calcification of breastfed rat cubs of mothers consuming excessive Arabica coffee
Authors: Apriyono Dwi Kartika , Shita Amandia Dewi Permana , Fatimatuzzahro Nadie , Prasetya Rendra Chriestedy , Umaimah Ulfa
Published: April 2024

Lack of nutrient intake, especially calcium, can inhibit tooth development because calcium is the major component of the inorganic material that forms enamel and dentin. Caffeine in coffee can decrease calcium levels in the body. Arabica coffee has a very high caffeine content compared to other types of coffee. Excessive caffeine consumption can cause the inhibition of PTH secretion. As a result, the nursing mother's body cannot absorb calcium optimally. This makes the baby lack calcium intake which is used for the dental calcification process. This study analyzes radiographic images of tooth calcification of rat cubs during lactation period from rat mothers which consumed excess doses of Arabica coffee. Forty-eight breastfeeding rat mothers (n = 48) were divided into a control group and a treatment group. The control group consisted of 24 rat mothers that were given aquadest. The treatment group consisted of 24 nursing rat mothers, which were given coffee orally at a dose of 2.7 grams/200 grams/day. After the rat mothers gave birth (H + 1 to H + 18), every 4 rat cubs were euthanized, then the mandibular bones were X-rayed. Dental calcification was viewed and analyzed based on radiographic images. The teeth of rat cubs whose mothers consumed excess doses of Arabica coffee experienced a delay in the calcification stage compared to the teeth of normal rat cubs. Consumption of Arabica coffee by nursing mothers can cause a delay in the stage of dental calcification in rat cubs.
Development of dentists perceptions and knowledge of teledentistry
Authors: Boanjoy Sarah Margareth , Setiawan Asty Samiaty , Suryanti Netty
Published: April 2024

Teledentistry is a dental health service that provides consultation, guidance, or education remotely using information technology. Perception and knowledge play an essential role in the implementation of teledentistry. The purpose of this study was to explore the development of dentists' perceptions and knowledge of the concept of teledentistry. This study used a scoping review method based on the Joanna Briggs Institute methodology. Screening and study selection were carried out using the Preferred Reporting Items of Systematic Reviews and Meta-Analysis Scoping Reviews (PRISMA-Scr). Literature searches were conducted through PubMed, Science Direct, and EBSCOHost with keywords and inclusion criteria, hand searching, and viewing the list of selected article references. There were 23 articles analyzed according to the inclusion and exclusion criteria. Changes in dentists' perceptions of teledentistry would help shorten waiting list, reduce costs for dental practice, additional visits to take photographs, and additional costs to provide facilities/ equipment for teledentistry before and during the COVID-19 pandemic. Three articles (2015-2016) state that most dentists did not know or have little knowledge about teledentistry. Nine articles published during the pandemic revealed that the majority of dentists had knowledge of teledentistry. The results of this study found that developments in dentists’ perception, namely teledentistry would help shorten waiting list, reduce costs for dental practice, the need for additional visits to take photographs, and additional costs to provide facilities/ equipment for teledentistry. The level of knowledge of dentists about teledentistry increased during the COVID-19 pandemic.
Optimization and Modeling for the use of Machine and Maintenance in Agricultural Production System in Allahabad District (Uttar Pradesh), India
Authors: Lal Abhishek Velerian , Singh Shankar , Singh Shera
Published: April 2024

This study constitutes the status of Machinery Power in Allahabad district based upon the survey conducted and data as references and hence proposing an estimated data of the current status of power utilization in Allahabad district and more specifically its three block; viz, Chaka-Block, Jasra-block and Shankargarh-block. Based on these three different block’s differences, the study was conducted for different farming system of Allahabad district to find the status of energy inputs and availability of farm machinery for particular system in blocks. The survey was carried out in the month of March to April, 2016 find the ". One hundred and sixty seven farmers were selected considering the owning improved implements of bullock, tractor and power operated categories were surveyed this study. The data were collected in the prescribed profarma (Appendices .A,B,C and E,F,G) w.r.t. farmers and implements separately, The data regarding farm machines and implements have also been collected from Block development office Allahabad, The survey data indicate that the number of implement per hector, cultivated area in different selected blocks was361.65%, 274.96% and 333.41% in Chaka, Jasra and Shankargarh, respectively with the district average of 36.3. The percentage of Chaff-cutter in different blocks varied from 16.66%,19.64% & 19.60% in Chaka, Jasra and Shankargarh blocks, respectively. Plant protection equipment was very low as the number of sprayer and duster75%,8.35% & 72.54% cultivated area in surveyed blocks. However, most of the farmers were using plant protection equipment and other machines on custom hiring basis. Power operated centrifugal pump sets were most common for under around water pumping and its availability was highest in Chaka block 10.71 % cultivated area followed by 13.33% and 11.76%in Jasra and Shankargarh blocks, respectively.
Определение цинка, меди, кадмия и свинца в говяжьей печени
Authors: Столбоушкина Т.П. , Стахеев А.А.
Published: April 2024

Приведены результаты измерений массовой доли цинка, меди, кадмия и свинца методами масс-спектрометрии с индуктивно связанной плазмой (ИСП-МС) и оптико-­эмиссионной спектрометрии с индуктивно связанной плазмой (ИСП-ОЭС) в образцах бычьей печени. Подобраны оптимальные для измерений параметры спектрометров и условия для проведения пробоподготовки образцов в системе микроволнового разложения проб, а также способ подготовки лабораторной пластиковой посуды. Аналитический метод валидирован путем измерений предела обнаружения, предела количественного определения, линейности, точности и относительного смещения данных. Полученные результаты сравнивали с сертифицированными значениями и оценивали относительную погрешность. Показано, что оба метода надежны и могут использоваться для определения содержания элементов в образцах бычьей печени.
KYPHOSIS IN THE SOUTHWESTERN POND TURTLE Actinemys pallida (EMYDIDAE) FROM BAJA CALIFORNIA, MEXICO
Authors: Valdez Villavicencio Jorge Heriberto , León-Serrano Brayan E. , Peralta-García Anny
Published: April 2024

Kyphosis is a physical condition defined as a dorsally convex deformity of the spine in the sagittal plane of the animal. During monitoring surveys of the southwestern pond turtle Actinemys pallida in Arroyo San Rafael, Baja California, we found two kyphotic individuals. Of 220 pond turtles captured at this site in several years, these two turtles were the only ones found with this type of malformation, representing low prevalence of this condition.
Using Technological Templates to Determine the Predicted Labor Intensity of Manufacturing Parts on CNC Lathes
Authors: Kugaevskii S.S. , Bogoyavlensky A.V.
Published: April 2024

The article considers the use of technological templates for calculating the predictive labor intensity of machining. The processing of parts of the “sleeve” type on CNC lathes is considered. The process of determining the predictive labor intensity of structural and technological elements (features) of a part is implemented as an applied CAD module. At the same time, the contour of previously recognized features in the form of an electronic 2D model and a table of processed surface parameters are fed to the module input. The use of technological algorithms becomes possible due to the preliminary automatic feature recognition, which is implemented as a module of the considered CAD. At the recognition stage, various types of features are classified (flat end, open area, semi-open area, closed area, and thread). The result of recognition is the contour of individual features, consisting of individual segments of straight lines and arcs of circles and specified in the form of standard G-codes. The article describes the principle of developing new mathematical models of technological templates for feature data processing. Technological templates include automatic selection of cutting tools from the user base, selection of a toolpath strategy and selection of processing modes. This takes into account the location of the contours relative to the axis of the part (internal and external), and for closed areas, their geometric type is taken into account (undercut, groove, groove for thread exit, end undercut, and etc.). Such decision-making algorithm detailing is necessary because the choice of tool and toolpath depends on it. In order to take into account the part properties, the coefficient of labor intensity of materials is introduced. Further, technological templates include algorithms that use feature contours described in the form of G-codes to generate a control program (NC) for a CNC machine. To determine the labor intensity, a standard NC-simulation module is used. The results of model adaptation for the current production type are obtained.
Case Study on Pavement Failures & Its Maintenance
Authors: Prasad Dr. B.
Published: April 2024

Abstract: A robust transportation infrastructure is critical to the nation's industrial, social, and cultural advancement. Humans have evolved three forms of transportation: air, sea, and land as a result of this requirement. From 4 lakh km in 1947 to 20 lakh km in 1993 and approximately 62 lakh km by March 31, 2020, the road network has grown. In India, the total length of all roads paved and unpaved is less than 5.13 km per 1000 inhabitants. Before we get into the maintenance section, we will try to concentrate on various defects and their causes. The research indicates that the definition of flexible pavement defects and their causes is the reduction in serviceability brought on by the development of various types of deterioration on the flexible pavement, such as cracks, surface defects, disintegration, etc. The breakdown of bituminous pavement can have numerous causes.
POSVENÇÃO: estratégias de enfrentamento para elaboração do luto por suicídio
Authors: Oliveira Ananda Nobre de , Rosendo Eva Victória Feitosa , Chagas Igor da Silva , Martins Lara Janiffer Vieira , Martins Michelle de Sousa Fontes , Diniz Dalciney Maximo
Published: April 2024

Introduction: Suicide is a complex and polysemic phenomenon, often unrecognized by society, making the grieving process difficult for bereaved survivors. The loss of a person in these circumstances is a delicate topic, and the support practices offered, known as a prevention of suicide, are essential. Objectives: the research aims to understand the mourning for suicide and discuss ways of coping afterward. Methodology: this is a review integrative bibliographic, exploratory and descriptive in nature. The bibliographic survey was carried out in reference books on the subject, in articles published in Scientific databases Electronic Library Online (SciELO-Brasil), Electronic Journals in Psychology (Pepsic) and Lilacs. Results: It was possible to highlight the impact experienced by family members bereaved by suicide, the role of health professionals in postvention, as well as actions, strategies and policies public information that can be used in this context. The surveys indicated different feelings present in mourning for suicide, among them, the feeling of guilt, the fear of being judged and the shame, in addition to the social stigmas that this theme imposes. Conclusion: there is a need to develop coping strategies, which involve postvention actions and interventions aiming at ways of coping with suffering and favoring the adaptation process of the bereaved. It is worth highlighting the importance of debating the phenomenon of suicide as a health problem public and postvention as a welcoming strategy for bereaved survivors.
Swimming Up Niagara Falls! The Battle to Get Disability Rights Added to the Canadian Charter of Rights and Freedoms
Authors: Lepofsky M. David
Published: April 2024

This is the personal memoir of blind lawyer and volunteer disability rights advocate David Lepofsky. It describes his involvement in and perspectives on the successful fight from 1980 to 1982 to get Canada’s proposed Charter of Rights amended to guarantee equal rights for people with disabilities. It includes a foreword by the Hon. Rosalie Abella, former Justice of the Supreme Court of Canada. This memoir recounts the little-known saga of the disability amendment to the Charter. Few know that equality for people with disabilities was the only constitutional right added to the Canadian Charter of Rights and Freedoms during the widely publicized eighteen-month battle over the patriation of Canada’s Constitution, from October 1980 to April 1982. It is aimed at anyone interested in disability rights, human rights, Canadian political or legal history, social justice advocacy, and Canadian constitutional law. It provides a mix of legal and legislative history, personal autobiography, grassroots advocacy strategy and reflective commentary on lessons learned. It compares social justice advocacy techniques in 1980 to those practiced in the disability rights arena four decades later.