bluuebunny/crossref_metadata_2025 huggingface dataset:
The social capital effect on HIV/AIDS preventive efforts: a meta-analysis
Authors: Nugraheni Reny ,   Doctoral Program of Public Health, Universitas Sebelas Maret, Surakarta, Indonesia,   Faculty of Health Technology and Management, Institut Ilmu Kesehatan Bhakti Wiyata, Kediri, Indonesia,   Reny Nugraheni, Doctoral Program of Public Health, Universitas Sebelas Maret, Surakarta, Indonesia. Faculty of Health Technology and Management, Institut Ilmu Kesehatan Bhakti Wiyata, Kediri, Indonesia. E-mail: reny.nugraha.RN@gmail.com, Murti Bhisma ,   Doctoral Program of Public Health, Universitas Sebelas Maret, Surakarta, Indonesia, Irawanto Muhammad Eko ,   Skin and Sexual Health Sciences, Universitas Sebelas Maret, Surakarta, Indonesia, Sulaiman Endang Sutisna ,   Medical Sciences, Universitas Sebelas Maret, Surakarta, Indonesia, Pamungkasari Eti Poncorini ,   Medical Sciences, Universitas Sebelas Maret, Surakarta, Indonesia
Published: November 2022

HIV/AIDS is one of the sexually transmitted diseases that cause death worldwide. Its prevalence increases due to low prevention behaviour. The study aimed to estimate the effect of social capital on HIV/AIDS preventive efforts. This study was a meta-analysis and systematic analysis. We retrieved articles from PubMed, Science Direct, and Google Scholar from 2008–2021. The inclusion criteria were full-text articles with observational design and articles published in English. We focused on the problems of the PICO study, namely: population=men and women who were sexually active; intervention=high social capital; comparison=low social capital; outcome=HIV/AIDS prevention efforts. The articles were collected using the PRISMA flow diagram. Meta-analysis was performed using RevMan 5.3 with a random effect model. The study included 12 articles. The likelihood of sexually active men and women with high social capital to perform HIV/AIDS prevention efforts was 1.55 times higher than those with low social capital (aOR=1.55; CI 95%=1.11 to 2.16; p=0.009).
Mothers’ knowledge, practice, and attitudes toward vitamin D deficiency among children in the Qassim region, Kingdom of Saudi Arabia
Authors: Bassam Samah El Awady ,   Department of Maternal and Child Health Nursing, College of Nursing, Qassim University, Qassim, Kingdom of Saudi Arabia,   Department of Pediatric Nursing, Faculty of Nursing, Zagazig University, Zagazig, Egypt,   Samah El Awady Bassam, Department of Maternal and Child Health Nursing, College of Nursing, Qassim University, Qassim, Kingdom of Saudi Arabia E-mail: awadysss@yahoo.com,   https://orcid.org/0000-0001-6284-6202, Abd-Elmageed Fawzia Nabeel Mohammad ,   Department of Pediatric Nursing, Faculty of Nursing, Zagazig University, Zagazig, Egypt
Published: November 2022

Vitamin D comes in two forms: ergocalciferol (D2) and cholecalciferol (D3). This study aimed to assess mothers' knowledge, attitudes, and practices toward vitamin D deficiency among children. We collected data using a self-administered online questionnaire to gather information about the characteristics, knowledge, attitudes, and reported practices of 800 Saudi Arabian mothers regarding vitamin D deficiency. The mean age of participants was 31.2±4.76, and 8% had a university education. When it came to household income, the majority (90.1%) reported that they had enough money. Participants who attended training courses, employed mothers, total practice, and total attitude had a significant favorable effect on knowledge, with a p-value of less than 0.01. Employed mothers, training course attendees, total practice, and overall attitude had a significant favorable effect on mothers' practice, with a p-value of less than 0.01**. More than half of the mothers who participated in the study had an inadequate level of understanding. Less than two-thirds of those surveyed noted the deficient practice. Two-thirds of the moms who participated in the study had a negative attitude toward vitamin D deficiency. There was a strong positive correlation between total knowledge, total attitude, and total practice-related vitamin D deficiency.
Immunological markers in type 1 diabetes mellitus in Thi-Qar province, southern Iraq
Authors: Hamadi Ghaneemah Malik ,   Department of Community Health, Nasiriyah Technical Institute, Southern Technical University, Nasiriyah, Iraq,   Ghaneemah Malik Hamadi, Department of Community Health, Nasiriyah Technical Institute, Southern Technical University, Nasiriyah, Iraq. E-mail: ghaneemahm@stu.edu.iq,   https://orcid.org/0000-0003-0811-7353
Published: November 2022

Type 1 diabetes mellitus (T1D) is a chronic autoimmune illness defined as insulin insufficiency resulting from the autoimmune breakdown of pancreatic beta cells producing insulin in the islets of Langerhans. Biomarkers are markers of physiological or pathological processes that are normal or abnormal, playing a crucial function in clinical evaluation, prognosis, and therapy response monitoring. This study aimed to investigate some biomarkers associated with T1D and examine the association between glutamic acid carboxylase (GADA) antibody and islet antigen-2 autoantibody (IA-2A) for β-cell stress and death in patients with T1D. The current study included 60 patients with T1D, 32 (53.33%) males and 28 (46.67%) females between 9 to 18 years old, and 30 healthy individuals as control. Glutamic acid carboxylase, islet antigen-2 autoantibody and connecting peptide levels in the blood were evaluated. Positive results for IA-2A and GADA were shown in 89.04% and 38% of T1D patients, respectively. The normal level frequency and C-peptide titer mean were significantly lower between T1D and healthy control. However, no statistically significant changes were observed in the C-peptide level among GADA positive and negative patients. Finally, the C-peptide concentrations were significantly lower for positive IA-2A compared to negative IA-2A persons. The combination of IA-2A, GADA, and C-peptide could indicate stronger diagnostic measures at a low cost for patients with T1D.
The effect of roselle leaf (Hibiscus sabdariffa L.) extract gel on wound healing
Authors: Rambe Puspita Sari ,   Department of Dermatology and Venereology, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia,   Puspita Sari Rambe, Department of Dermatology and Venereology, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia. E-mail: pipitrambe@gmail.com, Putra Imam Budi ,   Department of Dermatology and Venereology, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia, Yosi Ariyati ,   Department of Dermatology and Venereology, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia
Published: November 2022

Roselle (Hibiscus sabdariffa L.) belongs to the genus Hibiscus with proven anti-inflammatory, antioxidant, and antimicrobial properties. Scientific evidence associated roselle content with bioactive compounds, such as phenolic acids, flavonoids, and anthocyanin. Most studies focused on their petals, while research on leaf extract on wound healing has never been done. This study aimed to assess the effect of roselle leaf extract on wound healing in rats. This was an experimental laboratory study with a posttest-only control group design. There were 30 rats divided into 5 groups: negative control, 5%, 10%, and 15% roselle leaf extract, and positive control (bioplacenton). The parameters assessed in this research were wound size and histological assessment. The data were analyzed using ANOVA. P<0.05 was considered statistically significant. Wound healing percentage and epithelial thickness in the 15% group were the largest (84.17%; 64.69 µm). The lowest value was recorded in placebo (64%; 36.33 µm). Meanwhile, wound healing percentage and epithelial thickness of rats in the 5% and 10% groups were 68.53%, 43,57 µm, and 78.11%, 56.49 µm, respectively. Finally, positive control had a 77.44% wound healing percentage and 49.7 µm epithelial thickness. There were no significant differences in wound healing and epithelial thickness among the groups. Roselle leaf extract at 15% concentration showed greater wound healing properties based on clinical and histological assessment. Although there were no statistically significant differences, roselle leaf showed an opportunity to be further investigated as a potential wound healing therapy.
Accuracy of endometrial length measurement in predicting IVF/ICSI outcome
Authors: Nayyef Shaymaa Abdul-Sattar ,   Department of Obstetrics and Gynecology, Al-Yarmuk Teaching Hospital, Baghdad, Iraq,   Shaymaa Abdul-Sattar Nayyef, Department of Obstetrics and Gynecology, Al-Yarmuk Teaching Hospital, Baghdad, Iraq. E-mail: Shaima7835@gmail.com, Abdullah Thuraya Husamuldeen ,   Department of Obstetrics and Gynecology, Alimamain Alkathmain Medical City, Baghdad, Iraq, Al Obaidi Manal Taha ,   High Institute for Infertility Diagnosis & Assisted Reproductive Technologies (ART), Baghdad, Iraq
Published: November 2022

This study aimed to evaluate if endometrial length (EL) affects the likelihood of a positive pregnancy test in individuals who had in vitro fertilization/intra cytoplasmic sperm injection (IVF/ICSI). Between December 2020 and June 2021, 100 women from those referred to the High Institute for Infertility Diagnosis and Assisted Reproductive Technologies, Al-Nahrain University, for IVF/ICSI were selected. These women were 20–40 years old with primary type sub-fertility and met the inclusion criteria. Controlled ovarian hyperstimulation (antagonist protocol), followed by transvaginal sonography (TVS), was used to measure the endometrial length (EL) from the internal ostium to the fundus on the day of ovum collection. Afterwards, the association between endometrial length and the outcome was examined. The data were analyzed using the Statistical Package for Social Sciences (SPSS). The data show an important link between EL and treatment success. Endometrial length of ≥39 mm was considered a good cut-off point for IVF/ICSI pregnancy rates with a sensitivity of 75%, a specificity of 68%, a positive predictive value of 57%, and a negative predictive value of 83, and area under the curve of 0.81. An endometrial length of 39 mm can be used as an appropriate cut-off point in IVF/ICSI to predict a greater pregnancy rate. Vaginal sonography could be used in the ART cycle to measure the endometrial length and thickness and to determine endometrial receptiveness.
10-degree reverse Trendelenburg position on hemodynamic parameters and block characteristics in unilateral spinal anesthesia in below knee orthopedic surgeries – can head up position do the trick?
Authors: Bhandari Shyam ,   Department of Anesthesiology, Dr. RP Govt Medical College, Kangra, Himachal Pradesh, India, Kumar Manuj ,   Department of Anesthesiology, Dr. RK Govt Medical College, Hamirpur, Himachal Pradesh, India, Thakur Aman ,   Department of Anesthesiology, Dr. RP Govt Medical College, Kangra, Himachal Pradesh, India, Thakur Sunil ,   Department of Anesthesiology, Dr. RK Govt Medical College, Hamirpur, Himachal Pradesh, India,   Sunil Thakur, Department of Anesthesiology, Dr. RK Govt Medical College, Hamirpur, Himachal Pradesh, India. E-mail: sunil2044@gmail.com, Verma Ravinder Kumar ,   Department of Anesthesiology, Dr. RP Govt Medical College, Kangra, Himachal Pradesh, India, Awasthi Bhanu ,   Department of Orthopedics, Dr. RP Govt Medical College, Kangra, Himachal Pradesh, India
Published: November 2022

Unilateral spinal anesthesia (USpA) is a technique used to restrict the effect of the spinal block on the operative side. 10–15 degrees reverse Trendelenburg position has been used to control the height of the spinal block using hyperbaric drugs. We aimed to study the effect of the 10-degree reverse Trendelenburg position on the quality of block and hemodynamic stability in unilateral spinal anesthesia in this hospital-based, double-blind, randomized clinical trial. 60 patients of both sexes between 20–60 years of age, undergoing below-knee orthopedic surgeries, were randomized into 2 groups. In both groups, spinal anesthesia was given with 2 mL bupivacaine heavy (0.5%), and the lateral position was maintained for 10 mins. Group 2 patients were kept in a 10-degree reverse Trendelenburg position throughout the surgery. The hemodynamic parameters and block characteristics of the two groups were compared using Epi Info statistical software. The onset of sensory block was faster in Group 1 (recumbent) compared to Group 2 (reverse Trendelenburg). The two-segment regression time was longer in the second group. In group 2, 73.3% of patients reached a level at T8 or below T8, compared to 46.7% in Group 1. The duration of sensory block and anesthesia was longer in Group 2. We conclude that reverse Trendelenburg of 10 degrees immediately after spinal anesthesia significantly limits the level of sensory block and prolongs the duration of unilateral spinal anesthesia.
Electrolyte disturbances in a sample of hospitalized patients from Iraq
Authors: Ibrahim Suad Lateef ,   Department of Clinical Laboratory Sciences, Faculty of Pharmacy, University of Kufa, Kufa, Iraq, Alzubaidi Zubaida Falih ,   Department of Clinical Laboratory Sciences, Faculty of Pharmacy, University of Kufa, Kufa, Iraq,   Zubaida Falih Alzubaidi, Department of Clinical Laboratory Sciences, Faculty of Pharmacy, University of Kufa, Kufa, Iraq. E-mail: zubaidahf.mezaal@uokufa.edu.iq, Al-Maamory Fatma Abbas Dawood ,   Laboratories of Al-Imamain Al-Kadhimain Medical City, Ministry of Health, Baghdad, Iraq
Published: November 2022

Electrolyte disturbances are common in ill patients. Several conditions in the intensive care unit (ICU) might be responsible for developing electrolyte disorders, and medications may also contribute to these disturbances. The current study aimed to determine the frequency of electrolyte disturbances and assess the pattern of electrolyte imbalance in hospitalized patients, determining the possible effects of these electrolyte disorders. This cross-sectional study included patients admitted to the intensive care unit, respiratory care unit (RCU), and coronary care unit (CCU) at the Al-Sadar teaching hospital, Najaf, Iraq, from November 2020 to April 2021. The study collected data from two hundred patients regarding demographics, categories of ICUs at admission, comorbidities, and laboratory values at admission. Also, electrolyte levels at ICU admission and during hospitalization were collected from the medical database record. In addition, the patient's age, sex, fasting blood sugar (FBS), body mass index (BMI), B.urea, and creatinine were matched. Na+, K+, ionized Ca++, and Cl serum levels were significantly different during hospitalization. Comorbidities with predominant hypokalemia were found in 80.5%, hypochloremia in 73%, hypocalcaemia in 72%, and hyponatremia in 56.7% of hospitalized patients. Studying the effect of co-morbidities indicated a higher percentage (44%) of admitted patients with ischemic heart diseases, 38 (19%) with digestive diseases, 21 (10.5%) with orthopedic surgery in an emergency, 14 (7%) with pneumonia and lung diseases, 12 (6%) with diabetics, 18 (9%) with sepsis, and 9(4.5%) with seizure. Hospitalized patients may be at higher risk of developing combined electrolytes disorder associated with decreased serum levels of K+, Na+, Ca++, and Cl-. Thus, doctors and clinicians are recommended to observe electrolyte changes and correct them as they seem to negatively impact the outcome and prognosis.
Giant cell arteritis: a cause of temporomandibular joint claudication
Authors: Chu Eric Chun-Pu ,   New York Chiropractic and Physiotherapy Centre, Hong Kong SAR, China,   Eric Chun-Pu Chu, New York Chiropractic and Physiotherapy Centre, Hong Kong SAR, China E-mail: eric@nymg.com.hk, Chiang Rick ,   School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Australia
Published: November 2022

The purpose of this case report was to benefit the clinical recognition and conservative management of giant cell arteritis (GCA) in temporal arteries associated with jaw claudication. Giant cell arteritis is a systemic inflammatory vasculitis that affects medium-to-large-sized arteries. Primarily affecting arteries in heads, especially in temples, chronic GCA can result in secondary headaches and even polymyalgia rheumatica. This is a case report of a 68-year-old female with a 10-year history of GCA. The patient presented jaw claudication, headache, and joint stiffness over 6 months. The left palpable superficial temporal artery was thickened and tendered. A full-spine radiograph revealed uneven shoulders, imbalanced jaws, and moderate lumbar scoliosis. After nine months with conservative management, the patient was completely recovered from the symptoms with significantly improved radiographic parameters. Patients with GCA can present with jaw claudication. Physiotherapy and chiropractic collaborations are options for patients with GCA who suffer from the chronic adverse effect of medicines. Clinicians should be aware of the common clinical findings associated with GCA when rehabilitation treatment is planned.
The SHID wound classification system for diabetic foot ulcer patients: a validity study
Authors: Jais Suriadi ,   Department of Medical Surgical Nursing, Sekolah Tinggi Ilmu Keperawatan Muhammadiyah Pontianak, Pontianak, Indonesia,   Suriadi Jais, Department of Medical Surgical Nursing, Sekolah Tinggi Ilmu Keperawatan Muhammadiyah Pontianak, Pontianak, Indonesia. E-mail: suriadif@yahoo.com.au, Pratama Kharisma ,   Department of Medical Surgical Nursing, Sekolah Tinggi Ilmu Keperawatan Muhammadiyah Pontianak, Pontianak, Indonesia, Fahrain Jery ,   Department of Medical Surgical Nursing, Sekolah Tinggi Ilmu Keperawatan Muhammadiyah Pontianak, Pontianak, Indonesia, Junaidi Junaidi ,   Department of Medical Surgical Nursing, Sekolah Tinggi Ilmu Keperawatan Muhammadiyah Pontianak, Pontianak, Indonesia, Kardiatun Tutur ,   Department of Medical Surgical Nursing, Sekolah Tinggi Ilmu Keperawatan Muhammadiyah Pontianak, Pontianak, Indonesia, Kawuryan Uji ,   Department of Medical Surgical Nursing, Sekolah Tinggi Ilmu Keperawatan Muhammadiyah Pontianak, Pontianak, Indonesia
Published: November 2022

This study aimed to evaluate the predictive validity of the SHID (Suriadi, Haryanto, Imran dan Defa) wound classification system compared to TU (Texas University) and Wagner wound classification systems in Indonesia. A prospective cohort study included patients with diabetic foot ulcers at Kitamura wound clinic in Indonesia. A total of 111 diabetic foot ulcer patients were assessed with SHID, TU, and Wagner wound classification systems. Two postgraduate nursing students assessed 111 wounds of bedside patients and observed them for 4 weeks. The predictive validity test indicated that the cut-off score of ≤grade 2 for SHID was 74% and 97%, ≤grade IB for TU was 77% and 92%, then ≤grade 2 for Wagner was 84% and 71% for sensitivity and specificity, respectively. The area under the curve (AUC) in SHID, TU, and Wagner tools was 0.90 (95% CI: 0.828–0.950), 0.85 (95% CI: I0.766–0.910), and 0.86 (95% CI: 0.775–0.917), respectively. The Youden index for SHID, TU, and Wagner was 0.72%, 0.70%, and 0.55%, respectively. The wound classification systems are good tools for identifying diabetic foot ulcers. However, the newly developed SHID tool produced the best AUC and Youden Index values compared to the Wagner tool.
The complex involvement of the digestive tract in human defense behavior – structural and functional arguments
Authors: Savulescu-Fiedler Ilinca ,   Internal Medicine and Cardiology Department, Coltea Clinical Hospital, Bucharest, Romania,   Department 1 Medical Semiology, Faculty of Medicine, University of Medicine and Pharmacy Carol Davila, Bucharest, Romania, Gurghean Adriana Luminita ,   Internal Medicine and Cardiology Department, Coltea Clinical Hospital, Bucharest, Romania,   Department 1 Medical Semiology, Faculty of Medicine, University of Medicine and Pharmacy Carol Davila, Bucharest, Romania, Siliste Roxana-Nicoleta ,   Internal Medicine and Cardiology Department, Coltea Clinical Hospital, Bucharest, Romania,   Department 1 Medical Semiology, Faculty of Medicine, University of Medicine and Pharmacy Carol Davila, Bucharest, Romania,   Roxana-Nicoleta Siliste, Internal Medicine and Cardiology Department, Coltea Clinical Hospital, Bucharest, Romania. E-mail: silisterox@gmail.com; roxana.siliste@umfcd.ro
Published: November 2022

The digestive system has an innate monitoring and defense capacity, which allows the recognition and elimination of different dangerous substances. The complex analysis of the intestinal content comprises the cross-interactions between the epithelial cells, the enteroendocrine cells, the neural tissue and the cellular defense mechanisms. The enteric nervous system, also called "the enteric brain" or "the second brain" is the only neuronal network outside the central nervous system capable of autonomous reflex activity. The enteric nervous system activity is mostly independent of the central nervous system, but not in all aspects. In fact, even the enteral reflexes are a consequence of the bidirectional intestine-brain relation. The central nervous and enteric nervous systems are coupled through the sympathetic and parasympathetic branches of the autonomic nervous system. The gastrointestinal functions are regulated due to the interaction between the intrinsic neurons within the gastrointestinal wall and the extrinsic neurons outside the gastrointestinal tract. Here we provide an overview of the important role of the enteric brain in defensive behavior, as well as its structural and functional particularities that make it a special organ.
Reaching consensus: a scoping review on erectile disorder guidelines
Authors: Safaei Minoo ,   Department of Reproductive Health, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran, Maasoumi Raziyeh ,   Department of Reproductive Health, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran,   Nursing and Midwifery Care Research Center, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran,   Raziyeh Maasoumi, Department of Reproductive Health, Nursing and Midwifery Care Research Center, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran. E-mail: r.masoomie@gmail.com, Mahdavi Seyed Amirhosein ,   Legal Medicine Research Center, Legal Medicine Organization, Tehran, Iran, Ghadirian Laleh ,   Knowledge Utilization Research Center, Center for Academic and Health Policy, Tehran University of Medical Sciences, Tehran, Iran, Gelehkolaee Keshvar Samadaee ,   Men’s Health and Reproductive Health Research Center, Shahid Beheshti University of Medical Science, Tehran, Iran
Published: November 2022

Erectile disorder (ED) is the continuous or repeated inability to achieve an erection or maintain its firmness for an adequate amount of time during sexual intercourse. Given the importance of utilizing quality clinical practice guidelines (CPGs) for the diagnosis of ED, the research team conducted a scoping review of erectile disorder CPGs to address the questions based on the clinical guideline of the best quality. This scoping review was conducted in five steps: 1 – identification of the research question, 2 – identification of relevant studies, 3 – selection of studies, 4 – data extraction, 5 – summarizing and reporting the results. The initial search yielded 1,888 articles, CPGs and books but after primary and secondary screening by two appraisers, 9 CPGs were extracted. After that, the two appraisers examined the quality of these guidelines using the AGREE II tool. Eventually, 5 CPGs extracted. After reviewing 5 guidelines, 5 questions were answered. Overall, the CPGs had desirable overlap in response to the marked questions; nevertheless, there were some differences in details too. This review shows that the first and foremost principle in examining the affected individuals is taking a complete detailed history, followed by a physical examination and use of relevant questionnaires to complete the information necessary to diagnose the problem. The next step is to perform routine lab tests; hormonal profiles may also be checked, and if necessary, special tests should be performed based on an individual's conditions.
Predicting factors and outcomes of acute myocarditis in children – a 5-year experience in a teaching hospital from the Eastern province of Saudi Arabia
Authors: Albuali Waleed ,   Department of Pediatrics, College of Medicine, King Fahad Hospital, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia,   Waleed Albuali, Department of Pediatrics, College of Medicine, King Fahad Hospital, Imam Abdulrahman Bin Faisal University, Dammam, Kingdom of Saudi Arabia. E-mail: wbuali@iau.edu.sa,   https://orcid.org/0000-0002-4910-0999
Published: November 2022

Myocarditis in children is not very common, but the state of the disease is similar to viral influenza, making it challenging for a clinician to make an early diagnosis and treatment plan. Elevated levels of inflammatory biomarkers like C-reactive protein, serum lactate, troponin, and abnormal ECG may be helpful for high-index suspicion of myocarditis. This study aimed to determine the predicting factors and outcomes of acute myocarditis in children admitted to a teaching hospital in the Eastern province of Saudi Arabia. Complete medical records of 80 pediatric patients with acute myocarditis over 5 years (from 2015 to 2019) were retrieved, including demographic characteristics, laboratory investigations including cardiac enzymes (serum lactate, CPR, and troponin), and ECG findings for the diagnosis of myocarditis based on tachycardia and bradycardia. There were 22 (27.5%) mortalities that took place during the hospital stay. Low WBC (mmol/dl) levels were associated with in-hospital mortality (p 0.001), whereas high serum lactate levels (>2 mmol) were not. Association of troponin level (0.15ng/mL) was not significantly associated with mortality (p=0.496). The area under the ROC=0.947 (95% C.I: 0.88–1.0) revealed highly significant predictive validity at the 2.3 best cutoff point, having 90.9% and 87.9% sensitivity and specificity, respectively. Clinical factors and elevated biomarkers were associated with poor prognosis and in-hospital mortality in pediatric myocarditis. Serum lactate and troponin levels demonstrated high predictive validity for early diagnosis.
Impact of extended pre-scan written instructions on motion artifacts during head magnetic resonance imaging
Authors: Salih Suliman ,   Department of Radiology and Medical Imaging, Fatima College of Health Sciences, Abu Dhabi, United Arab Emirates,   Suliman Salih, Department of Radiology and Medical Imaging, Fatima College of Health Sciences, Abu Dhabi, United Arab Emirates. E-mail: salim_suliman@hotmail.com, Abdulaal Osamah ,   Department of Diagnostic Radiologic Technology, Faculty of Applied Medical Sciences, Taibah University, Medina, Saudi Arabia, Gameraddin Moawia ,   Department of Diagnostic Radiologic Technology, Faculty of Applied Medical Sciences, Taibah University, Medina, Saudi Arabia, Alhasan Mustafa ,   Radiologic Technology Program, Applied Medical Sciences College, Jordan University of Science and Technology, Irbid, Jordan, Hasaneen Mohamed ,   Department of Radiology and Medical Imaging, Fatima College of Health Sciences, Abu Dhabi, United Arab Emirates
Published: November 2022

This study aimed to assess the effect of extending pre-scan written instructions to patients undergoing head magnetic resonance imaging (MRI) examinations on motion artifacts. A controlled study was conducted in King Fahad Hospital at the Department of Radiology. A total of 100 patients were involved: 50 received only routine oral hospital instructions (control group), and another 50 received pre-scan extended written instructions besides routine oral hospital instructions (intervention group). The head MRI images were assessed regarding motion artifacts. Informed consent was obtained from all patients included in the study. The incidence of motion artifacts was significantly less in the intervention group than in the control group, 10% and 58%, respectively (p-value=0.001). The motion artifacts decreased significantly in the intervention group compared to the control group. Extending written information before an MRI scan could significantly reduce motion artifacts and improve image quality.
Salivary Candida albicans in asthmatic patients taking anti-asthmatic medication
Authors: Abidullah Mohammed ,   Department of Dental & Biomedical Sciences, Faculty of Dentistry, Al Baha University, Al Baha, Saudi Arabia,   Mohammed Abidullah, Department of Dental & Biomedical Sciences, Faculty of Dentistry, Al Baha University, Al Baha, Saudi Arabia. E-mail: mdabid2512@gmail.com, Sanober Arshiya ,   Department of Oral & Maxillofacial Surgery, Government Dental College & Hospital, Hyderabad, Telangana, India, Kumar Sandeep ,   Department of Public Health Dentistry, Government Dental College & Hospital, Hyderabad, Telangana, India, Gaddikeri Kavitha ,   Department of Oral Pathology, ESIC Dental College, Gulburga, Karnataka, India, Soorneedi Neeharika ,   Department of Oral Pathology and Microbiology, Malla Reddy Institute of Dental Sciences, Hyderabad, Telangana, India, Fatema Raia ,   Aspen Dental, Saint Peters, Missouri, United States of America, Ahmed Safaa Muneer ,   Tenet Diagnostics, Banjara Hills, Hyderabad, Telangana, India
Published: November 2022

Anti-asthmatic medication makes the oral habitat susceptible to opportunistic infections like Candida, causing oral candidiasis. This study aimed to estimate salivary Candida Albicans in asthmatic patients taking anti-asthmatics medication. A prospective study was performed at the Oral Pathology and Microbiology Department of S.B. Patil Dental College and Hospital, Bidar, Karnataka, India, between June 2018 to November 2018. The research comprised a total of 100 individuals, 50 of whom were asthmatics, and 50 healthy controls who were age and sex-matched to the asthmatics. Saliva was collected for 5–10 minutes in a sterile container, and samples were transferred to the laboratory in cold chain conditions. Serial dilution was prepared for the saliva samples, and 50:1 standard dilution was inoculated on SAD (Sabouraud Dextrose Agar) culture media by lawn culture method. Some part of the culture plate was inoculated with Candida organisms. 32 people had candida growth, and 18 individuals did not have any candidal development at all. 18 people were in the 400 CFU/ml group, and 32 individuals were in the 401 CFU/ml group, respectively. It was 0.000 in the 400 colony forming unit/milliliter group, and 27200 in the 401 CFU/ml group, with 0.00 being the median. There was a notable difference between study and control groups in terms of colony forming unit per milliliter (P=0.000). The growth of Candida in asthmatics patients is very high compared to healthy people. Anti-asthmatic medication makes the oral habitat prone to attack from opportunistic infections like oral candidiasis.
Second-look flexible ureteroscopy after RIRS – Holmium Moses versus TFL (Soltive)
Authors: Geavlete Bogdan ,   Department of Urology, Sanador Hospital, Bucharest, Romania,   Department of Urology, Sf. Ioan Emergency Clinical Hospital, Bucharest, Romania, Mareș Cristian ,   Department of Urology, Sf. Ioan Emergency Clinical Hospital, Bucharest, Romania,   Cristian Mareș, Department of Urology, Sf.Ioan Emergency Clinical Hospital, Bucharest, Romania. E-mail: dr.marescristian@gmail.com, Mulțescu Răzvan ,   Department of Urology, Sanador Hospital, Bucharest, Romania,   Department of Urology, Sf. Ioan Emergency Clinical Hospital, Bucharest, Romania, Georgescu Dragoș ,   Department of Urology, Sanador Hospital, Bucharest, Romania,   Department of Urology, Sf. Ioan Emergency Clinical Hospital, Bucharest, Romania, Geavlete Petrișor ,   Department of Urology, Sanador Hospital, Bucharest, Romania,   Department of Urology, Sf. Ioan Emergency Clinical Hospital, Bucharest, Romania
Published: November 2022

Retrograde intrarenal surgery (RIRS) is nowadays more and more indicated in pyelocaliceal stones. Holmium and Thulium lasers are the main lasers used. Fragmenting (basketing) or dusting, despite the new technology, still have residual stones (even having 250 microns). This study evaluates second-look flexible ureteroscopy for residual fragments. We analyzed 246 patients (October 2020–March 2022) on which we used Moses Holmium technology (187 cases) in Group 1 and Soltive Laser System (59 cases) in Group 2. The average stone size was 13.1 mm (range 11–29), and the average stone density was 1026 HU (range 870–1752). We used 270 µm for Ho: YAG laser and 150 µm for TFL. For Holmium, we applied energy 0.4J and frequency 80 Hz. For TFL, we applied fine dusting (0.15 J/100 Hz) and dusting (0.5 J/30 Hz). After three months, we practiced the second flexible ureteroscopy. Both groups were compared for completely visual stone-free rates. Stone-free rate at 3 months (second flexible ureteroscopy) was 86.63% (n=162/187) in Group 1 and 96,61% (n=57/59) in Group 2, respectively. The stone-free correlation with the CT preoperative evaluation was 160/187–85.56% for Holmium and 55/59–93.22% for TFL. We found residual stones after the second flexible ureteroscopy in 25 cases after Holmium laser treatment and only in 2 cases after TFL. In all these cases, we finally obtained zero residual stones. The second flexible ureteroscopy could achieve complete residual stone removal and real stone-free status. Despite a slight difference between these two laser technologies, the second look decreases the residual fragments.
Clinical and laboratory characteristics of children with neurological presentations of COVID-19: a single-center experience
Authors: Akram Nabeeha Najatee ,   Department of Pediatrics, Mustansiriyah University, Baghdad, Iraq,   Nabeeha Najatee Akram, Department of Pediatrics, Mustansiriyah University, Baghdad, Iraq. E-mail: nabiha@uomustansiriyah.edu.iq,   https://orcid.org/0000-0001-8964-8943, Ibrahim Basma Adel ,   Department of Pediatrics, Mustansiriyah University, Baghdad, Iraq,   https://orcid.org/0000-0002-8089-5216, Ali Sabah Mohsin ,   Department of Pediatrics, Mustansiriyah University, Baghdad, Iraq,   https://orcid.org/0000-0001-9483-0109, Nori Wassan ,   Department of Obstetrics and Gynecology, Mustansiriyah University, Baghdad, Iraq,   https://orcid.org/0000-0002-8749-2444
Published: November 2022

The study aimed to assess the frequency of neurological presentations of pediatric COVID-19 patients and compare the clinical and laboratory characteristics and the outcomes of those who presented with neurological complaints and those without complaints. A cross-sectional study enrolled 84 children diagnosed with COVID-19 at the emergency department over 12 months. All previously healthy children with a laboratory-confirmed diagnosis of COVID-19 were included in the study. The diagnosis of COVID-19 was made by positive PCR of a nasopharyngeal swab. Patients were divided into 2 groups: group 1 included COVID-19 patients with neurological complaints, and group 2 included COVID-19 patients with non-neurological complaints. Demographical, clinical, and laboratory characteristics were compared among groups. During the study period, 84 children aged 2 months-15years were diagnosed with COVID-19. Only 17 patients (20.2%) presented with new-onset neurological complaints. Seizure was the most common neurological complaint (58.8%), and febrile convulsion was the most frequent diagnosis of COVID-19 patients with neurological presentation (47.1%). C-reactive protein (CRP) and duration of hospitalization were higher in patients with neurological presentations, with P values of 0.002 and 0.001, respectively. All patients with neurological complaints survived the acute illness. Neurological symptoms were present in 20% of the COVID-19 pediatric patients, having higher CRP than patients with non-neurological presentations. CRP can be used as a reliable indicator for neurological symptoms in COVID-19 pediatric patients.
Effect of probiotics on the intestinal microbiota of patients with giardiasis and ascariasis
Authors: Pryshliak Oleksandra Yaroslavivna ,   Department of Infectious Diseases and Epidemiology, Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine, Protsyk Andrii Liubomyrovych ,   Department of Infectious Diseases and Epidemiology, Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine,   Andrii Liubomyrovych Protsyk, Department of Infectious Diseases and Epidemiology, Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine. E-mail: andrprofesor@gmail.com, Semaniv Mariana Volodymyrivna ,   Department of Microbiology, Virology and Immunology, Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine, Boichuk Oleksandr Petrovych ,   Department of Infectious Diseases and Epidemiology, Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine, Gerych Petro Romanovych ,   Department of Internal Medicine and Allergology, Ivano-Frankivsk National Medical University, Ivano-Frankivsk, Ukraine
Published: November 2022

Recently, many cases of mixed invasion by Giardia and ascarids have been registered. Gastrointestinal lesions in patients are often accompanied by dysbiotic changes. The aim was to study the effect of probiotics containing Saccharomyces bouvardias CNCM I-745 in the complex therapy of patients with giardiasis, ascariasis, and mixed invasion. 90 patients with giardiasis, ascariasis and mixed invasion were divided into 3 groups, depending on the type of invasion. Each group was divided into two subgroups, depending on the treatment (basic treatment and treatment with probiotics). When studying the state of the intestinal microbiota, the following changes were detected in all patients before treatment. The content of Bifidobacterium spp., Lactobacillus spp., Enterococcus spp. and the total content of E. coli was reduced. At the same time, there was an increase in the content of Peptostreptococcus spp., Bacteroides spp., E. coli with low enzymatic properties, hemolytic E. coli, opportunistic Enterobacteriaceae spp., Candida spp. and Staphylococcus spp. Under the influence of treatment, the subgroup with probiotics addition to the basic treatment, was more effective for all types of invasions. The use of probiotics containing Saccharomyces bouvardias CNCM I-745 in the complex therapy of patients with mixed invasion of giardiasis and ascariasis increased treatment efficiency following a significant improvement in intestinal microbiota.
Arrhythmia related to hypertensive left ventricular hypertrophy in Iraqi patients: frequency and outcome
Authors: Al Alwany Ameen Abdulhasan ,   College of Medicine, University of Baghdad, Baghdad, Iraq,   Ameen Abdulhasan Al Alwany, College of Medicine, University of Baghdad, Baghdad, Iraq. E-mail: ameen.a@comed.uobaghdad.edu.iq,   https://orcid.org/0000-0002-3535-4023
Published: November 2022

Left ventricular hypertrophy (LVH) caused by high blood pressure is linked to increased mortality and arrhythmia risk. This study aimed to evaluate arrhythmia in hypertensive patients due to left ventricular hypertrophy (LVH). A cross-sectional study was performed, assessing participants' blood pressure, echocardiography and electrocardiography, and Holter monitoring in certain cases. There were 300 hypertensive patients >18 years attending the cardiology unit of Baghdad medical city. The study was conducted between January–June 2022. The electrocardiograms at rest for 300 adults with hypertension were investigated. 130 (43.5%) were females, and 170 (56.5%) were males. The mean age of participants was 58 years. Forty-nine (16.3%) patients had arrhythmia. As compared to those without arrhythmia, participants with arrhythmia were older (62.3 vs. 56.1, p=0.03), had a greater prevalence of left ventricular hypertrophy (24.5% vs. 12.7%, p=0.026), and more prone to experience cardiac failure (32.7% vs. 8.5%, p<0.011). Atrial fibrillation was found in 6 (27.2%) female patients and 5 (18.5%) males. In addition, two (7.4%) male patients and one female patient (4.5%) had atrial flutter, and premature ventricular contractions (PVCs) were noted in 10 (37%) and 11 (50%) patients. Left ventricular mass index (LVMI) was 103 gm/m2 in female patients and 119.2 gm/m2 in males. Palpitation was present in 22 (44.9%) female patients and 27 (55.1%) males. The study revealed that hypertensives with LVH have an arrhythmia frequency of 16.3%. The most common arrhythmias were atrial fibrillation and premature ventricular complex.
The cooperative behavior and intention to stay of nursing personnel in healthcare management
Authors: Muchlis Nurmiati ,   Faculty of Public Health, Universitas Muslim Indonesia, Makassar, Indonesia, Amir Haeril ,   Faculty of Public Health, Universitas Muslim Indonesia, Makassar, Indonesia,   Haeril Amir, Faculty of Public Health, Universitas Muslim Indonesia, Makassar, Indonesia. E-mail: haeril.amir@umi.ac.id, Cahyani Desy Dwi ,   Midwifery Department, Poltekkes Kemenkes Malang, Malang, Indonesia, Alam Rizqy Iftitah ,   Faculty of Public Health, Universitas Muslim Indonesia, Makassar, Indonesia, Landu Nurfitri ,   Scholl of Nursing, STIK Makassar, Makassar, Indonesia, Mikawati Mikawati ,   Nursing Study Program, STIKES Panakukang, Makassar, Indonesia, Febrianti Nur ,   Nursing Study Program, Akademi Keperawatan Justitia, Palu, Indonesia, Junaidin Junaidin ,   Nursing Study Program, Stikes Amanah Makassar, Makassar, Indonesia, Sinaga Mei Rianita Elfrida ,   Nursing Study Program, Sekolah Tinggi Ilmu Kesehatan Bethesda Yakkum Yogyakarta, Yogyakarta, Indonesia
Published: November 2022

The management of human resources is essential in a hospital, and its success can be seen based on the turnover rate of nursing personnel (nurses and midwives). In a hospital, the nursing personnel represents the largest number of professionals, and its performance greatly affects the effectiveness of services for patients. This study examined how organizations can predict turnover rates through intention to stay. Furthermore, this study aimed to explain the influence of cooperative behavior (both perceived external prestige and internal respect that affects organizational identification), which correlates with the intention to stay of nursing personnel. This quantitative research had a cross-sectional design, using a survey. The population involved non-permanent workers in five private and government hospitals. The sample consisted of 147 respondents. This study indicates that cooperative behavior showed positivity and significantly influenced the intention to stay, based on a 95% confidence degree. Perceived external prestige (p=0.009) and perceived internal respect (p=0.002) showed positivity and significantly influenced organizational identification. Perceived internal respect directly influenced the intention to stay (p=0.000), and organizational identification showed positivity and significantly influenced the intention to stay (p=0.000). Hospital management is more active in improving efforts and programs to improve the behavior of cooperatives, which is actually more dominant in non-financial aspects.
Breast cancer: age incidence, hormone receptor status and family history in Najaf, Iraq
Authors: Khalaf Hasan ,   Department of General Surgery, Kufa Medical College, University of Kufa, Kufa, Iraq,   Hasan Khalaf, Department of General Surgery, Kufa Medical College, University of Kufa, Kufa, Iraq. E-mail: hasankhalaf88@yahoo.com,   https://orcid.org/0000-0002-4162-5029, Mohammed Alaa ,   Department of Surgery, Dentistry College, Islamic University, Najaf, Iraq,   https://orcid.org/0000-0001-5413-7481, Shukur Sinan ,   Department of General Surgery, Kufa Medical College, University of Kufa, Kufa, Iraq,   https://orcid.org/0000-0002-7756-1856, Alhalabi Noor ,   Department of Medicine, Faculty of Medicine, University of Kufa, Kufa, Iraq,   https://orcid.org/0000-0001-8426-1280, Almothafar Basim ,   Department of General Surgery, Kufa Medical College, University of Kufa, Kufa, Iraq,   https://orcid.org/0000-0003-2874-2295, Hassan Mustafa ,   School of Medicine, University of Jordan, Amman, Jordan,   https://orcid.org/0000-0001-7975-2237, Abu Abduelraheim ,   Faculty of Medicine, University of Kordofan, El Obeid, Sudan,   https://orcid.org/0000-0001-5147-6904
Published: November 2022

Breast cancer is the primary type of cancer affecting women. Patients with hormone receptor-positive cells have lower mortality rates. Both chemotherapy and hormone therapy can improve the survival rate. This study aimed to evaluate the hormonal receptor status in female breast cancer and assess the relationship with the patient's age and family history in Najaf, Iraq. A prospective study of two-hundred and fifty-one women with mastectomies (for cancers) was performed at AL Sader Medical City from January 2019 to January 2021. We collected and analyzed data regarding the age of patients, site and size of the tumor, number of pregnancies, family history, weight, smoking, and hormone receptor status. The average age of patients was 48 years, and the peak incidence was in the 40–49 age group (30.27% of patients). Of all age groups, 48.6% (122 patients) were negative for all hormone receptors (triple negative), and only 22.70% had a positive family history. The peak incidence of cancer in our study was in the 40–49 years group. A high proportion of the hormone receptors for patients were negative (triple-negative), and most patients had a negative family history.
Correction to: The levels of oxidative stress in a combination of stress factors
Authors: Ilderbayev Oralbek ,   Department of General Biology and Genomics, Faculty of Natural Sciences, L.N. Gumilyov Eurasian National University, Nur-Sultan, Kazakhstan,   Oralbek Ilderbayev, Department of General Biology and Genomics, Faculty of Natural Sciences, L.N. Gumilyov Eurasian National University, Nur-Sultan, Kazakhstan. E-mail: oralbekzainuld@rambler.ru,   https://orcid.org/0000-0002-8137-4308, Okassova Assem ,   Department of General Biology and Genomics, Faculty of Natural Sciences, L.N. Gumilyov Eurasian National University, Nur-Sultan, Kazakhstan,   https://orcid.org/0000-0002-3022-9741, Rakhyzhanova Saule ,   Department of Physiological Disciplines, Semey Medical University, Semey, Kazakhstan,   https://orcid.org/0000-0001-5507-0610, Ilderbayeva Gulzhan ,   Department of Biotechnology and Microbiology, Natural Science Faculty, NCJSC L.N. Gumilyov Eurasian National University, Nur-Sultan, Kazakhstan,   https://orcid.org/0000-0002-5854-8410, Zhazykbayeva Lashyn ,   Department of Propaedeutics of Internal Diseases, Semey Medical University, Semey, Kazakhstan,   https://orcid.org/0000-0001-6529-284X, Musaynova Assem ,   Department of Physiological Disciplines, Semey Medical University, Semey, Kazakhstan, Zharmakhanova Gulmira ,   Department of Natural Science Disciplines, Marat Ospanov Medical University, Aktobe, Kazakhstan
Published: November 2022

This corrects the article on p. 927 in vol. 15, PMID: 36188645.