bluuebunny/crossref_metadata_2025 huggingface dataset:
Quantitative Control of Early Flowering in White Lupin (Lupinus albus L.)
Authors: Rychel-Bielska Sandra , Surma Anna , Bielski Wojciech , Kozak Bartosz , Galek Renata , Książkiewicz Michał
Published: April 2021

White lupin (Lupinus albus L.) is a pulse annual plant cultivated from the tropics to temperate regions for its high-protein grain as well as a cover crop or green manure. Wild populations are typically late flowering and have high vernalization requirements. Nevertheless, some early flowering and thermoneutral accessions were found in the Mediterranean basin. Recently, quantitative trait loci (QTLs) explaining flowering time variance were identified in bi-parental population mapping, however, phenotypic and genotypic diversity in the world collection has not been addressed yet. In this study, a diverse set of white lupin accessions (n = 160) was phenotyped for time to flowering in a controlled environment and genotyped with PCR-based markers (n = 50) tagging major QTLs and selected homologs of photoperiod and vernalization pathway genes. This survey highlighted quantitative control of flowering time in white lupin, providing statistically significant associations for all major QTLs and numerous regulatory genes, including white lupin homologs of CONSTANS, FLOWERING LOCUS T, FY, MOTHER OF FT AND TFL1, PHYTOCHROME INTERACTING FACTOR 4, SKI-INTERACTING PROTEIN 1, and VERNALIZATION INDEPENDENCE 3. This revealed the complexity of flowering control in white lupin, dispersed among numerous loci localized on several chromosomes, provided economic justification for future genome-wide association studies or genomic selection rather than relying on simple marker-assisted selection.
Synaptic Reshaping and Neuronal Outcomes in the Temporal Lobe Epilepsy
Authors: Ren Elisa , Curia Giulia
Published: April 2021

Temporal lobe epilepsy (TLE) is one of the most common types of focal epilepsy, characterized by recurrent spontaneous seizures originating in the temporal lobe(s), with mesial TLE (mTLE) as the worst form of TLE, often associated with hippocampal sclerosis. Abnormal epileptiform discharges are the result, among others, of altered cell-to-cell communication in both chemical and electrical transmissions. Current knowledge about the neurobiology of TLE in human patients emerges from pathological studies of biopsy specimens isolated from the epileptogenic zone or, in a few more recent investigations, from living subjects using positron emission tomography (PET). To overcome limitations related to the use of human tissue, animal models are of great help as they allow the selection of homogeneous samples still presenting a more various scenario of the epileptic syndrome, the presence of a comparable control group, and the availability of a greater amount of tissue for in vitro/ex vivo investigations. This review provides an overview of the structural and functional alterations of synaptic connections in the brain of TLE/mTLE patients and animal models.
PSEN1 Compound Heterozygous Mutations Associated with Cerebral Amyloid Angiopathy and Cognitive Decline Phenotype
Authors: Palmieri Ilaria , Valente Marialuisa , Farina Lisa , Gana Simone , Minafra Brigida , Zangaglia Roberta , Pansarasa Orietta , Sproviero Daisy , Costa Alfredo , Pacchetti Claudio , Pichiecchio Anna , Gagliardi Stella , Cereda Cristina
Published: April 2021

Cerebral amyloid angiopathy (CAA) is a cerebrovascular disorder caused by the deposition of amyloid beta-peptide (Aβ) aggregates. Aβ aggregates lead to vessel rupture and intracerebral hemorrhages, detected by magnetic resonance imaging (MRI). Presenile CAA is usually genetically determined by mutations in the amyloid precursor protein (APP) gene. However, mutations after codon 200 in the presenilin 1 (PSEN1) gene have been reported to facilitate CAA onset. Here, we analyzed the genetic bases in a patient of 55 years old affected by CAA and cognitive decline. DNA was isolated and genetic analysis was performed by Next-Generation Sequencing (NGS). RNA was extracted and retro-transcribed to perform segregation analysis by TOPO-TA cloning. WB analysis was carried out to check the impact of the mutations on protein. Two compound heterozygous mutations in PSEN1 exon 10, such as a novel stop-gain mutation (c.1070C > G) and a pathogenic splice variant (c.1129A > T), were found by NGS. Both mutations altered the presenilin 1 protein, truncating its C-terminal portion. This is the first case of CAA and cognitive decline caused by two compound mutations in PSEN1. With this report, we suggest extending the genetic analysis to PSEN1 when cerebral microbleeds are observed by MRI investigation in a patient affected by presenile cognitive decline.
The Zinc-Sensing Receptor GPR39 in Physiology and as a Pharmacological Target
Authors: Laitakari Anna , Liu Lingzhi , Frimurer Thomas M. , Holst Birgitte
Published: April 2021

The G-protein coupled receptor GPR39 is abundantly expressed in various tissues and can be activated by changes in extracellular Zn2+ in physiological concentrations. Previously, genetically modified rodent models have been able to shed some light on the physiological functions of GPR39, and more recently the utilization of novel synthetic agonists has led to the unraveling of several new functions in the variety of tissues GPR39 is expressed. Indeed, GPR39 seems to be involved in many important metabolic and endocrine functions, but also to play a part in inflammation, cardiovascular diseases, saliva secretion, bone formation, male fertility, addictive and depression disorders and cancer. These new discoveries offer opportunities for the development of novel therapeutic approaches against many diseases where efficient therapeutics are still lacking. This review focuses on Zn2+ as an endogenous ligand as well as on the novel synthetic agonists of GPR39, placing special emphasis on the recently discovered physiological functions and discusses their pharmacological potential.
Enhancing Anti-Tumoral Potential of CD-NHF by Modulating PI3K/Akt Axis in U87 Ex Vivo Glioma Model
Authors: Luta Gabriel , Butura Mihail , Tiron Adrian , Tiron Crina E.
Published: April 2021

Background: In the latest years, there has been an increased interest in nanomaterials that may provide promising novel approaches to disease diagnostics and therapeutics. Our previous results demonstrated that Carbon-dots prepared from N-hydroxyphthalimide (CD-NHF) exhibited anti-tumoral activity on several cancer cell lines such as MDA-MB-231, A375, A549, and RPMI8226, while U87 glioma tumor cells were unaffected. Gliomas represent one of the most common types of human primary brain tumors and are responsible for the majority of deaths. In the present in vitro study, we expand our previous investigation on CD-NHF in the U87 cell line by adding different drug combinations. Methods: Cell viability, migration, invasion, and immunofluorescent staining of key molecular pathways have been assessed after various treatments with CD-NHF and/or K252A and AKTVIII inhibitors in the U87 cell line. Results: Association of an inhibitor strongly potentiates the anti-tumoral properties of CD-NHF identified by significant impairment of migration, invasion, and expression levels of phosphorylated Akt, p70S6Kinase, or by decreasing expression levels of Bcl-2, IL-6, STAT3, and Slug. Conclusions: Using simultaneously reduced doses of both CD-NHF and an inhibitor in order to reduce side effects, the viability and invasiveness of U87 glioma cells were significantly impaired.
A Combined Experimental and First-Principles Based Assessment of Finite-Temperature Thermodynamic Properties of Intermetallic Al3Sc
Authors: Gupta Ankit , Tas Bengü , Korbmacher Dominique , Dutta Biswanath , Neitzel Yulia , Grabowski Blazej , Hickel Tilmann , Esin Vladimir , Divinski Sergiy V. , Wilde Gerhard , Neugebauer Jörg
Published: April 2021

We present a first-principles assessment of the finite-temperature thermodynamic properties of the intermetallic Al3Sc phase including the complete spectrum of excitations and compare the theoretical findings with our dilatometric and calorimetric measurements. While significant electronic contributions to the heat capacity and thermal expansion are observed near the melting temperature, anharmonic contributions, and electron–phonon coupling effects are found to be relatively small. On the one hand, these accurate methods are used to demonstrate shortcomings of empirical predictions of phase stabilities such as the Neumann–Kopp rule. On the other hand, their combination with elasticity theory was found to provide an upper limit for the size of Al3Sc nanoprecipitates needed to maintain coherency with the host matrix. The chemo-mechanical coupling being responsible for the coherency loss of strengthening precipitates is revealed by a combination of state-of-the-art simulations and dedicated experiments. These findings can be exploited to fine-tune the microstructure of Al-Sc-based alloys to approach optimum mechanical properties.
Effect of Wave Process of Plastic Deformation at Forging on the Fatigue Fracture Mechanism of Titanium Compressor Disks of Gas Turbine Engine
Authors: Shanyavskiy Andrey A. , Soldatenkov Alexey P. , Nikitin Alexandr D.
Published: April 2021

The low-cycle fatigue behavior of the VT3-1 titanium alloy (Ti–6Al–3Mo–2Cr alloy) under loading with a triangular and trapezoidal shape of cycle waveform was studied on round specimens prepared from forged compressor disks of a gas turbine engine. The filament type structure after forging has alternating filaments with the ductile and quasi-brittle state of the metal as a result of the wave process of plastic deformation during the metal forging process. The crack propagation, regardless of the cyclic waveform shape, occurs by the crack meso-tunneling mechanism: initially, the cracks propagate along the filaments by a quasi-brittle mechanism with the formation of a facetted pattern relief on the fracture surface reflecting the two-phase structure of the titanium alloy, and then, the bridge between the meso-tunnels is fractured with the formation of fatigue striations. The part of the crack growth duration Np/Nf in the durability Nf is determined on the basis of measuring the fatigue striation spacing, and it depends on the crack path with respect to the material filaments. The growth of a fatigue crack in the case of in-service failure of a compressor disk of a gas turbine engine is considered, taking into account the crack meso-tunneling effect, and the fatigue crack growth duration in the disk is determined on the basis of quantitative fractography.
Reactivity of Aliphatic and Phenolic Hydroxyl Groups in Kraft Lignin towards 4,4′ MDI
Authors: Antonino Leonardo Dalseno , Gouveia Júlia Rocha , de Sousa Júnior Rogério Ramos , Garcia Guilherme Elias Saltarelli , Gobbo Luara Carneiro , Tavares Lara Basílio , dos Santos Demetrio Jackson
Published: April 2021

Several efforts have been dedicated to the development of lignin-based polyurethanes (PU) in recent years. The low and heterogeneous reactivity of lignin hydroxyl groups towards diisocyanates, arising from their highly complex chemical structure, limits the application of this biopolymer in PU synthesis. Besides the well-known differences in the reactivity of aliphatic and aromatic hydroxyl groups, experimental work in which the reactivity of both types of hydroxyl, especially the aromatic ones present in syringyl (S-unit), guaiacyl (G-unit), and p-hydroxyphenyl (H-unit) building units are considered and compared, is still lacking in the literature. In this work, the hydroxyl reactivity of two kraft lignin grades towards 4,4′-diphenylmethane diisocyanate (MDI) was investigated. 31P NMR allowed the monitoring of the reactivity of each hydroxyl group in the lignin structure. FTIR spectra revealed the evolution of peaks related to hydroxyl consumption and urethane formation. These results might support new PU developments, including the use of unmodified lignin and the synthesis of MDI-functionalized biopolymers or prepolymers.
A Multi-Layer LoRaWAN Infrastructure for Smart Waste Management
Authors: Baldo David , Mecocci Alessandro , Parrino Stefano , Peruzzi Giacomo , Pozzebon Alessandro
Published: April 2021

Long Range Wide Area Network (LoRaWAN) has rapidly become one of the key enabling technologies for the development of Internet of Things (IoT) architectures. A wide range of different solutions relying on this communication technology can be found in the literature: nevertheless, the most part of these architectures focus on single task systems. Conversely, the aim of this paper is to present the architecture of a LoRaWAN infrastructure gathering under the same network different typologies of services within one of the most significant sub-systems of the Smart City ecosystem (i.e., the Smart Waste Management). The proposed architecture exploits the whole range of different LoRaWAN classes, integrating nodes of growing complexity according to the different functions. The lowest level of this architecture is occupied by smart bins that simply collect data about their status. Moving on to upper levels, smart drop-off containers allow the interaction with users as well as the implementation of asynchronous downlink queries. At the top level, Video Surveillance Units (VSUs) are provided with machine learning capabilities for the detection of the presence of fire nearby bins or drop-off containers, thus fully implementing the Edge Computing paradigm. The proposed network infrastructure and its subsystems have been tested in a laboratory and in the field. This study has enhanced the readiness level of the proposed technology to Technology Readiness Level (TRL) 3.
Factors Affecting Outbound Open Innovation Performance in Bio-Pharmaceutical Industry-Focus on Out-Licensing Deals
Authors: Kim Eungdo , Lee InGyu , Kim Hongbum , Shin Kwangsoo
Published: April 2021

Due to the high risk in development process, the bio-pharmaceutical industry has transformed itself into an open innovation framework in order to overcome economic risk. This study examines the relationship between outbound open innovation and financial performance in bio-pharmaceutical industry. Specifically, this study extends knowledge-based view to link the open innovation performance and licensor’s sustainability. In order to provide empirical evidence, this study uses econometric methodology with several databases including bio-pharmaceutical firms. The analysis shows firm’s desorptive capabilities have a significant effect on financial performance, confirming the application of knowledge capacity framework. The result of the study can suggest the way how the licensors can maintain the sustainability of competitiveness in bio-pharmaceutical industry.
LC and LC-IRT Models in the Identification of Polish Households with Similar Perception of Financial Position
Authors: Genge Ewa
Published: April 2021

One of the pillars of sustainable development is related to the elimination of poverty and improvement of quality of life. Financial situation of the households plays a crucial role in the subjective well-being, quality of life and overall satisfaction. According to most recent Eurostat data, Poland is one of the countries with the lowest level of subjective material well-being. In this paper we aim to find latent structures of Poles with similar tendency of self-reporting their income position additionally influenced by the socio-economic features and analyze the item characteristics of the questionnaire as well. To address the questions at hand, first we apply the variant of finite mixture models, i.e., latent class (LC) model for data from all, eight waves (2000–2015) of the Polish Household Panel. We are especially focused on the constrained version of the model under IRT parameterization. We compare the results for LC and LC-IRT models and show the influence of the covariates such as family type, socio-economic status and place of living on the probability of belonging to the three identified classes of Polish households, based both on multinomial and global logit parameterization. In this way we can show which types of families tend to be more satisfied with their financial position and those whose members are prone to belong to the worst situated group of Poles. Note that, we present the results for the data including survey weighs, being omitted in most of the studies concerning Polish financial well-being.
Development and Characterization of a cDNA-Launch Recombinant Simian Hemorrhagic Fever Virus Expressing Enhanced Green Fluorescent Protein: ORF 2b’ Is Not Required for In Vitro Virus Replication
Authors: Cai Yingyun , Yu Shuiqing , Fang Ying , Bollinger Laura , Li Yanhua , Lauck Michael , Postnikova Elena N. , Mazur Steven , Johnson Reed F. , Finch Courtney L. , Radoshitzky Sheli R. , Palacios Gustavo , Friedrich Thomas C. , Goldberg Tony L. , O’Connor David H. , Jahrling Peter B. , Kuhn Jens H.
Published: April 2021

Simian hemorrhagic fever virus (SHFV) causes acute, lethal disease in macaques. We developed a single-plasmid cDNA-launch infectious clone of SHFV (rSHFV) and modified the clone to rescue an enhanced green fluorescent protein-expressing rSHFV-eGFP that can be used for rapid and quantitative detection of infection. SHFV has a narrow cell tropism in vitro, with only the grivet MA-104 cell line and a few other grivet cell lines being susceptible to virion entry and permissive to infection. Using rSHFV-eGFP, we demonstrate that one cricetid rodent cell line and three ape cell lines also fully support SHFV replication, whereas 55 human cell lines, 11 bat cell lines, and three rodent cells do not. Interestingly, some human and other mammalian cell lines apparently resistant to SHFV infection are permissive after transfection with the rSHFV-eGFP cDNA-launch plasmid. To further demonstrate the investigative potential of the infectious clone system, we introduced stop codons into eight viral open reading frames (ORFs). This approach suggested that at least one ORF, ORF 2b’, is dispensable for SHFV in vitro replication. Our proof-of-principle experiments indicated that rSHFV-eGFP is a useful tool for illuminating the understudied molecular biology of SHFV.
Escolas técnicas
Authors: Gonçalves Ivani Maria de Souza , Silva Genilda Maria da , Carvalho Odair França de
Published: April 2021

A interdisciplinaridade é uma proposta que visa a ruptura do ensino fragmentado. Assim, discute-se, que a reflexão sobre essa proposta, no contexto de ensino técnico, consiste em um processo de grande complexidade. Nesse sentido, objetiva-se compreender, como a interdisciplinaridade é desenvolvida e entendida pelos professores que atuam como docentes em uma escola técnica no município de Petrolina – PE. Dessa forma, destaca-se que estes debates se apoiam em Fazenda (2001 – 2008), Japiassu (1994), Morin (2015), na LDB/1996. Para tanto, realizou-se uma pesquisa qualitativa, a qual contou com a participação de quatro professores do curso de enfermagem, que responderam a um questionário aberto. Os dados revelam, que os professores fomentam a importância da interdisciplinaridade e a compreendem como possibilidade de ruptura de uma ação educativa fragmentada. Assim, conclui-se que, existe uma relação entre o ensino técnico e o fazer interdisciplinar dos docentes, que atuam com educação técnica no lócus de estudo.
À la recherche d’un droit transnational des changements climatiques
Authors: Lassus Saint-Geniès Géraud de
Published: April 2021

L’implication des entités privées dans la lutte contre les changements climatiques est un fait bien acquis. Elle est à l’origine d’une activité normative intense et diversifiée. Cette activité se manifeste notamment par la production de certaines normes climatiques qui, outre leur origine privée, possèdent aussi une dimension internationale, en raison de la déterritorialisation de leur champ d’application. Ce constat invite alors à s’interroger sur l’existence d’un éventuel droit transnational des changements climatiques qui évoluerait en marge du droit national et international des changements climatiques. Prenant appui sur les réflexions qui ont été menées à propos du droit transnational dans d’autres domaines de réglementation, cette étude entend ainsi apporter quelques éléments de réponse au sujet de la possible existence d’un droit transnational des changements climatiques.
Commentaire de la loi relative à la Transition Énergétique pour la Croissance Verte
Authors: Denolle Anne-Sophie
Published: April 2021

La loi relative à la transition énergétique pour la croissance verte (TECV) apparaît sous certains aspects de portée limitée, se bornant à fixer des objectifs vagues et à poser de simples incitations à agir. Mais la loi TECV ne peut se résumer ainsi. Composée de 215 articles, elle renvoie nécessairement à des dispositions prescriptives et techniques, censées concrétiser la transition énergétique. La loi TECV a, qui plus est, le mérite d’aborder la problématique énergétique dans sa globalité, en traitant non seulement des énergies renouvelables mais également de l’isolation des bâtiments, de l’enjeu du développement des transports propres, de la nécessité de fonctionner en circuits-courts en favorisant une économie circulaire moins énergivore.
МОДЕЛЮВАННЯ ПРОЦЕСУ ДЕЗІНТЕГРАЦІЇ РУДНОЇ ПОРОДИ В БАРАБАННОМУ МЛИНІ З ВИКОРИСТАННЯМ МЕТОДУ СКІНЧЕНИХ ЕЛЕМЕНТІВ
Authors: Маліч Микола
Published: April 2021

Розглянуто особливості руху рудних матеріалів в барабанному млині. Розроблено математичну модель процесу подрібнення рудних матеріалів з позиції балансу енергетичних величин процесу руйнування За використанням методу скінчених елементів показано, що виділений в будь-якому місці елемент завантаження піддається деформації з боку сусідніх елементів завантаження (шматків руди) в умовах всебічного нерівнокомпонентного стиснення контактними силами. Проаналізовано вплив напрямку сил контактного тертя при стисненні на ефективність руйнування рудної маси Данні сили суттєво впливають на появу максимальних зсувних (дотичних) напружень, які залежать від максимальних нормальних напружень, що виникають в шматках рудної породи Показана можливість керування режимами навантаження для підвищення ефективності процесу подрібнення.
Impact of COVID-19 on the Corporate Governance: A Case Study on Bajaj Finance Ltd and Infosys
Authors: Patra Samira , Das Jnanaranjan
Published: April 2021

Introduction: The Novel Coronavirus has been bringing various revolutionary dynamic aspects to the World. It taught us many useful lessons. The COVID-19 has an impact on almost all human and economic activities. Lakhs of people have retrenched from their jobs in the India Corporate Sectors. The Indian Corporate Sectors have been affected slightly in the Financial Year 2019- 20, but it will have a severe impact in the current and future financial years. It can also seem in the Corporate Governance of the different companies in India. It has inherent commercial risks impacting business operations due to disruptions to Meetings, Dividends, Liquidity, Disclosure, Capital Allocation, Risk Management, and Internal Control.Research Gap: A lot of researches have been undertaken on the impact of COVID-19 in India. No remarkable studies have been conducted on the Impact of COVID-19 in the Corporate Governance of Bajaj Finance Ltd and Infosys.Objectives: This paper attempt to study the impact of COVID-19 on the Corporate Governance of Bajaj Finance Ltd and Infosys.Research MethodologyNature and Sources of Data: The present study is based on secondary data. The secondary data have been collected through a well-designed strategy. These have been collected from various e-journals, e-magazines, e-annual reports of companies, and various reputed websites.Tools of Analysis: There are various statistical tools, i.e., percentage calculations, correlation, and t-Test have used for analysis and interpretation of results.Conclusions: COVID-19 pandemic comes with inherent commercial risks impacting business operations due to disruptions to Meetings, Administration, Business Continuity, Dividend and Liquidity management, Disclosure, Capital Allocation, and Maintenance, and lastly, risk management and Internal Control.
The Mahatma Gandhi National Rural Employment Guarantee Act (MGNREGA) - An Overview
Authors: Konakuntla Rayappa V , Bavaiah M D
Published: April 2021

Mahatma Gandhi National Rural Employment Guarantee Scheme (MNREGS) was introduced in 2006 by the Government of India to provide 100 days’ assurance employment for the poor rural citizen to make their employment security. The Mahatma Gandhi NREGA sponsors various schemes for helping rural people below the poverty line for the construction of wage employment and productive assets, but this scheme has either both advantages and disadvantages due to many reasons; hence, this study reviews the clear perspective of people on this above system. Besides, the purpose of this study is to provide an overview of the MGNREGA scheme for easy access and reference by researchers, which will be supportive for a policymaker to advance the scheme.
Meta Analysis of Study Habits and Academic Achievement
Authors: Elango M , Manimozhi G
Published: April 2021

A Meta analytical review investigated the study habits and academic achievement of school and college students. In this study the sample consists of twenty seven reviews based on study habits and academic achievement/ performance. The sample of the review based on inclusion criteria such as study habits and academic achievement. The review was collected by following details such as title of the study, Name of the author, Sample of the study, correlation Value and findings of the study. The Meta analysis is on the relationship between study habits and academic achievement. The main aim of the study is to find the fixed effects, random effects model values, Heterogeneity and forest plots. A Meta analysis of research paper was formed the conclusion.
The Iksvaku Dynasty: An Expanded Genealogy of the Kings of Mithila
Authors: Kumar Chitra
Published: April 2021

The ancient Indian texts ‘Puranas’ are voluminous compendiums of information and have been passed down through the ages – sometimes being split into sub-volumes, sometimes getting combined or appended with additional content. Over time, large portions of the original text have been lost to antiquity. While there is much published on the genealogy and lineage of the branch of the Iksvaku dynasty of which Lord Rama is the most famous son, there is very little known about the ancestry and lineage of that branch of the Iksvaku dynasty of which Sita, the illustrious wife of Lord Rama is the most famous daughter. In the current study, a portion of the lineage of the kings of Mithila, including the ancestors and successors of King Janaka (father of Sita), are elaborated. The study of this text yields the names of nearly 40 kings of the dynasty of Iksvaku descended from Nemi.
Scope of Introducing TPACK of Teacher Education Programme in India
Authors: Das Kaushik , Mittra Swarnali
Published: April 2021

The present study focused on the scope of introducing Technological Pedagogical Content Knowledge (TPACK) of a two-year pre-service and in-service teacher education program in India. This paper describes the TPACK awareness among teacher educators. It also emphasizes teachers educators integrate technology into education in the 21st century. The main objective of the study to find out the scope of implementation of TPACK on Teacher training programs & the relationship between technology and pedagogy content. Also, the researcher measures the curriculum and challenges to introducing TPACK and finally gives meaningful suggestions to gain technological skills. The methodology of the study is qualitative and interview methods are applied. The study is a mixed type involving interpretative, analytical study of documents, interview and study both primary & secondary sources, like books, university news, expert opinion, articles, journals, thesis and websites, etc.
Is Volunteerism Effective in Building Capacities of Rural Women for Development Works? - A Global to Local Perspective
Authors: Rajan M , Anandharaja Kumar P
Published: April 2021

The works of Government and Non-Government efforts to nurture the development consciousness among rural women through various initiatives and volunteerism have been widely accepted. The voluntary efforts exponentially paved the way for development action and people’s participation among marginalized sections. This article explores and tries to understand the role of volunteerism in building capacities of rural women for development works in a local perspective through the international and national initiatives and its importance.
Determinants of Gender Responsive Spending in Rural Families in Tamil Nadu
Authors: Ramasubramanian M , Selvarani G , Puthira Prathap D , Senthil Kumar M , Anuratha A
Published: April 2021

A study was conducted among 120 as respondents in Six villages of Madurai district with the objective of analysing the determinants for gender neutral spending in families and to predict their willingness to spend gender neutrally. Ex-post facto research design was employed and the respondents were selected using random sampling procedure. The data was collected using a well-structured interview schedule. The results revealed that among the determinants differential needs of sons/daughters, earning of husband and wife, urge for giving good education, perceived importance of the issue, availability of money for spending were found to be highly influencing the respondents to spend gender neutrally in families. Similarly, Influence on relatives on spending decisions, influence of neighbours on spending decision, social values, spending for health were the determinants which were moderately influencing the gender neutral spending in families. Binary Logistic Regression results revealed that the willingness of a parent improves 18 times if he/she is influenced by differential need of son and daughters. Further, it was found that, if a parent is influenced by urge for giving good education, the odds of his/her willingness to neutrally spend in families would increase by a factor of 17.58 units.
ANALISIS KESTABILAN TITIK TETAP PADA MODEL MATEMATIKA PENYEBARAN HIV/AIDS
Authors: Lamusu Moch. Fahmi , Mamula Dewinta , Muhsana Fitriyani
Published: April 2021

Artikel ini membahas tentang virus yang merusak sistem kekebalan tubuh, dengan menginfeksi dan menghancurkan sel CD4, yaitu virus HIV (human immunodefiency virus). Infeksi HIV yang tidak segera ditangani akan berkembang menjadi kondisi yang serius yang disebut AIDS (Acquired Immune Defiency Syndrome). Tujuan penulisan artikel ini adalah Mengetahui model epidemik SIA pada penularan penyakit HIV/AIDS, Mengetahui titik kesetimbangan dan melakukan analisis kestabilan dan Mengetahui penularan dan pencegahan penyakit HIV/AIDS. Hasil pembahasan menunjukkan jika kedua kota dalam kondisi endemik HIV/AIDS dibuktikan dengan nilai . Jika maka hanya terdapat satu titik kesetimbangan bebas penyakit yang stabil.  maka terdapat dua titik kesetimbangan, titik kesetimbangan bebas penyakit yang tidak stabil, dan titik kesetimbangan endemi yang stabil.
PERBANDINGAN REGRESI LOGISTIK BINER DAN PROBIT BINER DALAM PEMODELAN TINGKAT PARTISIPASI ANGKATAN KERJA
Authors: Dukalang Hendra H.
Published: April 2021

Regression is a data analysis method used to model the relationship between one response variable and one or more predictor variables. In regression modelling, data is often used. In general, the regression model that is often used is simple or multiple regression in modelling where the response variable is quantitative data. The fundamental difference from regression models using quantitative data is the main objective is to estimate the average value of the dependent variable using certain values of the independent variable. Whereas in a regression model with a qualitative dependent variable the main objective is to find the probability of something happening (probability model). One of the development methods of the regression model for data with qualitative response variables is Logistic and Probit regression. The purpose of this study was to compare the best model using binary logistic regression with binary probit regression in the case of Labor Force Participation Rate (TPAK) in Gorontalo City. The research method used is quantitative research methods, with binary logistic regression modelling and binary probit regression. The results showed that the variable that has a significant effect on TPAK Gorontalo City is the open unemployment rate, and the best model between the binary logistic regression model with an AIC value of 1.289 is smaller than the AIC value of the binary Probit regression 1.318, likewise from the R2 value the R2 value for regression is obtained. binary logistic of 12.74%, greater than the R2 value of binary probit regression of 10.70%.
Exact solutions of the Benney–Luke equation via (1/G')-expansion method
Authors: DURUR Hülya , YOKUŞ Asıf
Published: April 2021

In this study, the (1/G') -expansion method was implemented to solve the Benney–Luke (BL) equation. Exact solutions of the BL equation were obtained via this method. The solutions obtained from the BL equation were in hyperbolic form. 3D, 2D and contour graphs of obtained solutions are presented. Results show that the (1/G') -expansion method provides an efficient and straightforward mathematical instrument for finding solutions of nonlinear evolution equations (NLEEs).
Organik bileşik olarak Altın çilek (Physalis peruviana) kabuk ve meyve özütü ile çiçek şekilli hibrit nanoyapıların gıda patojenleri üzerine antibakteriyel etkisinin incelenmesi ve bu nanoyapıların morfolojik karşılaştırılması
Authors: DEMİRBAŞ Ayşe
Published: April 2021

Bu çalışmada, altın çilek meyve ekstresi-bakır (II) (Cu2+) iyonları nanoflower (NFs) ve altın çilek kabuk ekstresi-bakır (II) (Cu2+) iyonları nanoflower (NFs) sentezlendi. Ve bu sentezlerin gıda kaynaklı bakteriyel patojenler (Staphylococcus aureus, Escherichia coli, Aeromonas spp. ve Basillus cereus) üzerine antimikrobiyal etkisi ayrıca sentezlenen çiçek şekilli hibrit nanoyapıların morfolojileri incelendi. Altın çilek kabuğu ekstresinin (AÇKE) ve altın çilek meyve ekstresinin (AÇME) ana bileşikleri organik bileşenler olarak ve bakır (II) (Cu2 +) iyonları inorganik bileşenler olarak sentezlendi. AÇME-Cu2+ nanoflowerları, AÇKE-Cu2+ nanoflower'lara kıyasla oldukça kompakt, gözenekli ve üniformdur. NF'lerin yapılarını gözlemlemek için Fourier Dönüşümü Kızılötesi spektrometresi (FT-IR), Taramalı Elektron Mikroskobu (SEM) ve Enerji Dağılımlı X-ışını (EDX) spektroskopisi kullanıldı. FT-IR'nin bulguları, NF'deki Cu-O ve Cu-N bağlarını gösterir ve bu NF'lerin gelişiminin bir göstergesi olabilir. Bununla birlikte, AÇME-hNF'lerin ve AÇKE-hNF'lerin gıda patojenlerine karşı antimikrobiyal etkileri doğrulandı. HNF'lerin antimikrobiyal etkilerinin bitki özlerindeki negative veya pozitif yüklü moleküller ile bağantılı olabileceği bununda NF'ler arasındaki reaksiyonu artırabileceği söz konusu olabilir.
Los armónicos que aportan los sistemas fotovoltaicos interconectados a la red un problema latent
Authors: Delgado-Ponce Luis , Vargas-Hernández Oscar Joel , Martínez-Magdaleno Arturo , Menéndez-Benavente Luis Martín
Published: April 2021

The electric power that generators supply to users (in Mexico, CFE), requires specifications for the safe and efficient operation of equipment and machinery. An important part of an interconnected photovoltaic system is the inverter and because it is a non-linear load, it will inevitably distort the voltage sine wave, whose components can be harmful for the aforementioned equipment, depending on the degree of total harmonic distortion that results from the operation of these investers The problem of the harmonics originated by the SFVI increases because of two situations: 1. The current trend of the use of this type of systems is increasing, due to the economic, environmental and social benefits. 2. the way of connection for SFVI called distributed generation, produce electricity close to the end users of power, means the harmonic components of the distorted wave will have greater impact. This study of harmonic distortion generated in the invester, it is urgent to analyze and determine procedures and specifications to select the best equipment and to minimize this latent phenomenon, which unfortunately can not be eliminated, but only to reduce its effects.
Simulación en la Ingenieria
Authors: Martínez-Marín Francisco Alejandro , Medina-Lozano Alejandra , Cantú-Munguía Irma Adriana , Martínez-Mendoza María Lizbeth
Published: April 2021

Simulation is a method by which you can test, experiment or predict results in a certain process, scenario or object without the risk of real consequences. The objective of this research is to demonstrate how simulation is one of the greatest tools in engineering, which is used to represent a process through another and makes it much simpler and more understandable. This simulation is, in some cases, almost indispensable. In the simulation work, a methodology for design, development and evaluation is proposed. It is based on the synergy of two apparently dissimilar fields of knowledge: software engineering on the one hand and modern learning theories on the other, but which converge on the generation of a desirable product: simulation software. This methodology is based on the application of existing rules in both fields. As a result we have the use of simulation software, as a numerical technique to conduct experiments in a digital computer. These experiments involve certain types of mathematical and logical relationships, which are necessary to describe the behavior and structure of complex real-world systems over long periods of time.
Controlador de servomotores industriales mediante un microcontrolador utilizando MicroPython
Authors: Rodríguez-Ponce Rafael
Published: April 2021

Electrical motors are indispensable machines in the industry, thus it is necessary to ensure that engineering students can develop speed and torque controllers, in a fast and efficient manner. One of the most commonly used motor control strategies is Field Oriented Control; however it’s implementation requieres highly-intensive math processing and a fast processor with robust hardware resources. Several related works have been published, but they are hard to replicate and use due to the aforementioned problems. In this article, the author presents a torque and speed controller for industrial servomotors by means of Direct Torque Control which is known for its speed and ease of implementation compared to Field Oriented Control. In addition, the MicroPython programming language is used on the new and novel ESP32 microcontroller, which allows greater design simplicity. Results were validated using simulations and a physical implementation, thus achieving adequate motor funcionality. This work will provide students and researchers interested in industrial motor control, a fast and effective implementation tool.
Sobre la síntesis óptima de mecanismos
Authors: Foster-Vázquez Ixshel Jhoselyn , Portillo-Vélez Rogelio De Jesús , Vazquez-Santacruz Eduardo
Published: April 2021

In the engineering design process, it is of particular relevance the problem statement that has to be solved to guarantee an optimal design. There is no general rule for this, and in the particular case of the synthesis of flat mechanisms, the solution strongly depends on the problem statement for the design or mechanism synthesis. The object this paper is presenting one proposal at synthesis problem of a four-bar flat mechanism for cartesian trajectory tracking. The mechanism synthesis problem is stated as a nonlinear optimization problem with non linear constraints. Four different approaches are considered in order to demonstrate the impact of the considered statement of the optimization problem for its solution. The solution of the four optimization problems is obtained by means of numerical calculations using genetic algorithms. The numerical results of the four optimization problem statemens are compared under fair circumstances and they depict the great influence of the initial problem statement for its solution.
Simulación del Modelo Matemático de la Cinemática Diferencial de Robots Seriales Planos Configuración RRR y RPR
Authors: Martinez-Zamudio Patricio , Gonzalez-Villela Victor , Leon-Nuñez Hector
Published: April 2021

This article presents the model and simulation of the serial robot configurations of the types RRR and RPR, applying the theories of differential kinematics, to obtain the representation of its mathematical model (Jacobian matrix) and its simulation. The differential kinematics in robotics is the relationship between vector spaces, so it is possible to make the velocity map in the joint space in the end effector workspace. We present the differential kinematic model that is obtained from the position kinematics by differentiation techniques and with the help of the asymmetric matrix we obtain the information that is part of the Jacobian matrix, which allows us to know the velocities of the joint variables as a function of linear and angular velocity in the end effector and vice versa. The simulation of the manipulators is carried out validating the mathematical differential model; through the validation of the differential kinematics of serial chains it is possible to apply the procedure to complicated manipulator robots. The method presented here is the basis of a useful tool for solving complex robots, as in the case of redundant, parallel and hybrid serial manipulator robots.
Mecanismo Diseñado y Simulado Virtualmente
Authors: Jiménez-Rabiela Homero , Vazquéz-González Benjamín , Ramírez-Cruz José Luis , García-Segura Pedro
Published: April 2021

Objectives: To show a process to synthesize and analyze a crank mechanism oscillator function generator. Simulate it in a virtual reality environment, without losing its physical characteristic. Evaluate deviations between analytically desired and virtually obtained. Methodology: Using the analytical method described by Hartenberg and Denavit, a graphic package and an electronic spreadsheet; knowing the angle of rotation of the crank, the angular reference position of the crank, the displacement of the oscillator, the extreme values of the independent variable and the function; precision positions, link lengths, eccentricity and oscillator reference position were determined. The links were generated, the mechanism was assembled, analyzing fifteen of its positions. Of the infinite number of existing solutions, five were synthesized. For each solution that justify it, the deviation of the generated function was evaluated with respect to the desired one. Contribution: The friendly, fast, safe, accurate and parametric process was demonstrated; modifying the inputs and checking the update of the outputs, therefore it is a contribution to the scientific progress of the area.
Peran Islamic Corporate Social Responsibility dalam Memoderasi Pengaruh Zakat Terhadap Kinerja Bank Umum Syariah
Authors:   Universitas Ahmad Dahlan, Wardiwiyono Sartini , Jayanti Arty Fitria ,   Universitas Ahmad Dahlan
Published: April 2021

The aim of this study is to investigate the role of Islamic Corporate Social Responsibility in moderating the effect of zakat on Islamic commercial banks’ financial performance. Out of 13 Islamic commercial bank listed by Otoritas Jasa Keuangan from 2012 to 2017, there were only five banks reporting Statement of Zakat Fund Sources and Disbursements. Hence, the final samples of this study consist of 30 observation data. Secondary data collected from 30 annual reports were gathered through documentation. This study utilizes moderated regression analysis to test three research hypotheses. The results shows several findings. Firstly, the amount of corporate zakat being reported in the Statement of Zakat Fund Sources and Disbursements has positive impact on Islamic banks’ financial performance. Secondly, Islamic CSR as measured by Islamic reporting index developed by Belal et al. (2015) has negative impact on Islamic Banks’ financial performance. Thirdly, the role of Islamic CSR in moderating the effect of zakat on financial performance was confirmed.
PERINEAL URETHROSTOMY: JOURNEY REVISITED
Authors: Shringi Udipt , Jain Nilesh , Saini Ashutosh , Goyal Shailendra
Published: April 2021

Introduction: Hesitation to offering a perineal urethrostomy to a patient is on the false belief that the
satisfaction in regards to urination and sexual performance is low. Method: We have done observational
descriptive study and evaluated 50 patients. We included patients between the ages of 40-70 years with urethral stricture
diseases and excluded patients who were having PFUD disease and those who have not completed their family. Quality of life is
calculated using validated questionnaire by PROM-USS. Results: Most of our patients were in 60-70 years' age group 30/50 i.e.
60%. Most common aetiology of stricture was idiopathic (18) followed by iatrogenic (15), traumatic (9) and post infectious (8).
Average length of stricture was more than 6 cm and involving anterior urethra. Patients were followed up for median 14 months.
Preoperative IPSS score was 27+/- 4.5 and postoperative was 9+/- 5. SHIM scoring preoperative and postoperative were same
~ 21. PROM-USS for LUTS was signicantly reduced from median of 19 to 8.5 and QOL from median of 5.5 to 2. Success rate
with previous urethrotomy, urethroplasty, multiple treatment and no treatment patients were 15/17(88%), 9/12(75%), 11/14(78%),
7/7(100%) respectively. Most of the patients were satised with the procedure. And few of them (3) reported that postejaculatory
dysfunction bothering them. In patients in whom second surgery was indicated that is in patients with bladder outlet obstruction
the endoscopic procedure was done without any difculty. Conclusions: These reports will likely increase the acceptance of
perineal urethrostomy by patients and as well as urologists.
ROLE OF SUBCUTANEOUS NEGATIVE-PRESSURE DRAIN IN CASES OF EMERGENCY LAPAROTOMIES
Authors: Gandhi Anshoo S. , Shinde Viraj C. , Khwaja Rizwanuddin M.
Published: April 2021

Surgical Site infection is one of the common complications in patients who underwent emergency laparotomies, leading to postoperative complications, purulent discharge, prolonged hospital stay, increased cost of treatment, increased morbidity etc. Even after culture sensitivity -based antibiotic use and judicious irrigation of wound with saline, it has remained a major concern.(1) Aims and objectives: 1. To evaluate the role of subcutaneous Negative-pressure Drain in reduction of postoperative Surgical Site infection in cases of Emergency laparotomies when compared to laparotomy wounds without subcutaneous Negative-pressure drain. 2. To evaluate whether Subcutaneous Negative-pressure Drain is effective in reducing the hospital stays. 3. To evaluate whether Subcutaneous Negative-pressure Drain is effective in reducing the cost of treatment. 4. To evaluate whether Subcutaneous Negative-pressure Drain helps in early healing of wound and removal of sutures. Materials and methods: This study is conducted on patients who underwent emergency laparotomies and we divided it into two groups: one with Subcutaneous Negative-pressure Drain in and other without it. Conclusion: Subcutaneous Negative-pressure Drain prevented postoperative wound infection signicantly, reduces hospital stay, reduces cost of treatment, and helped in early healing of wound and removal of sutures.