bluuebunny/crossref_metadata_2025 huggingface dataset:
KARAKTERISTIK BELAJAR GENERASI Z DAN IMPLIKASINYA TERHADAP DESAIN PEMBELAJARAN IPS
Authors: Hayati Early Ni’mah
Published: January 2025

Perkembangan teknologi digital telah memberikan dampak signifikan terhadap gaya belajar dan preferensi Generasi Z dalam proses pembelajaran, khususnya dalam mata pelajaran Ilmu Pengetahuan Sosial (IPS). Artikel ini menjelaskan karakteristik belajar Generasi Z yang lahir dan tumbuh di era digital serta implikasinya terhadap desain pembelajaran IPS. Metode penelitian yang digunakan adalah kualitatif deskriptif dengan studi literatur. Hasil penelitian menunjukkan bahwa Generasi Z cenderung belajar secara mandiri melalui sumber daya online, seperti YouTube maupun platform lain, dan responsif terhadap pembelajaran visual dan interaktif. Implikasi terhadap desain pembelajaran IPS mencakup integrasi teknologi, pendekatan pembelajaran visual, pemberian fleksibilitas, adaptabilitas, serta pentingnya interaksi sosial dan kolaboratif. Kesimpulannya, penyesuaian dan inovasi dalam pendekatan pembelajaran diperlukan untuk memenuhi kebutuhan belajar Generasi Z secara efektif.
PENGEMBANGAN E-LKPD INTERAKTIF BERBASIS LITERASI PADA MATERI KELISTRIKAN SEL SARAF MANUSIA
Authors: Na’ilatul M Emilia , Hidayah Indriati Nurul , Rahmania Ika
Published: January 2025

Perkembangan pendidikan di Indonesia tahun 2023, sekolah sudah menggunakan kurikulum merdeka dalam proses pembelajarannya. Kurikulum ini menerapkan konsep pembelajaran yang disebut sebagai merdeka belajar. Pemanfaatan TIK (Teknologi Informasi dan Komunikasi) dalam pembelajaran dapat melalui penggunaan bahan ajar berbasis TIK dengan memanfaatkan teknologi elektronik, yang mana interaksi yang terjadi antara guru dan siswa, siswa dan siswa, ataupun antara sesama guru dapat berlangsung dengan mudah tanpa dibatasi aturan. Terkait dengan isu yang telah diuraikan, peneliti tertarik untuk melakukan studi pengembangan bahan ajar E-LKPD interaktif berbasis literasi pada materi kelistrikan sel saraf manusia. Penelitian pengembangan bertujuan untuk mengembangkan ELKPD, mengukur tingkat kepraktisan, dan mengukur tingkat keefektifan hasil belajar peserta didik. Model pengembangan yang digunakan pada penelitian ini yakni ADDIE (analisis, desain, pengembangan, implementasi, dan evaluasi). Teknik analisis data yang digunakan dalam penelitian ini adalah analisis deskriptif kuantitatif dan kualitatif. Teknik pengumpulan data meliputi lembar validasi, angket, wawancara, dan dokumentasi dengan menerapkan teknik persentase. Uji coba produk bahan ajar akan dilakukan di SMP Negeri 6 Malang kelas IX.2. Berdasarkan evaluasi dari validator ahli desain dan materi, respon peserta didik, respon guru, dan uji keefektifan hasil belajar peserta didik, dapat disimpulkan bahwa E-LKPD interaktif berbasis literasi pada materi kelistrikan sel saraf manusia dengan bantuan Live worksheets sangat layak untuk diimplementasikan dalam pembelajaran IPA pada kelas IX.
PENGEMBANGAN MEDIA RUPER UNTUK MENGENALKAN UNSUR-UNSUR KIMIA DALAM SISTEM PERIODIK
Authors: Fauzi Muhamad Andi , Setiawan Deny
Published: January 2025

Penelitian ini bertujuan untuk mengenalkan unsur kimia dalam sistem periodik dikemas dalam media RUPER. Selain untuk permainan, media RUPER juga dapat meningkatkan pemahaman peserta didik pada materi unsur khususnya. Metode yang digunakan adalah penelitian dan pengembangan dengan model 4D (Define, Design, Development, dan Disseminate) yang dibatasi hingga tahap pengembangan. Subjek penelitian adalah 10 peserta didik yang dapat mengoperasikan rubik’s cube serta telah/sedang menempuh materi unsur dan senyawa. Media RUPER untuk mengenalkan unsur-unsur kimia dalam sistem periodik dinyatakan sangat layak oleh ahli materi dan media dengan kategori “Sangat Layak” dengan presentase 87% dan masuk kategori “Layak” oleh pengguna dengan presentase 80%.
PENANAMAN NILAI-NILAI KEBHINEKAAN MELALUI PEMBELAJARAN KOLABORASI PADA KEGIATAN OUTING CLASS DI SMKN 10 MALANG
Authors: Khoiriyah Lutfiatul Ulfa , Putri Novilia Eka , Ersanda Privera Ajeng , Widiadi Nugroho
Published: January 2025

Kajian ini membahas mengenai penanaman nilai-nilai kebhinekaan melalui pembelajaran kolaborasi pada kegiatan outing class di SMKN 10 Malang. Penulisan ini menggunakan metode studi kepustakaan dengan mengkaji berbagai sumber literatur yang relevan, serta menggunakan hasil observasi dan dokumentasi. Hasil dari penulisan kajian ini adalah peserta didik di SMKN 10 Malang berasal dari suku, ras, agama, dan budaya yang berbeda. Dengan adanya keberagaman tersebut, maka perlu ditanamkan paradigma berpikir positif dalam menyikapi perbedaan. Upaya menjaga keberagaman dan menanamkan nilai-nilai kebhinekaan di SMKN 10 Malang yakni dengan menerapkan pembelajaran kolaborasi pada kegiatan outing class di berbagai situs bersejarah bagi siswa kelas X dan XI. Sehingga, dengan adanya penanaman nilai-nilai kebhinekaan menjadikan peserta didik mempunyai kualitas dalam meningkatkan kesabaran, toleransi, dan solidaritas.
PENERAPAN PEMBELAJARAN SOSIAL EMOSIAONAL UNTUK MENINGKATKAN HASIL BELAJAR: SEBUAH KAJIAN LITERATUR
Authors: Tsary Dina Ika , Widarti Hayuni Retno
Published: January 2025

Pembelajaran sosial-emosional merupakan sebuah kerangka kerja yang dikembangkan oleh Collaborative for Academic, Social and Emotional Learning (CASEL). Berbagai penelitian menunjukkan bahwa pembelajaran sosial-emosional mampu memberikan dampak positif terhadap prestasi akademik atau hasil belajar peserta didik. Sehingga, pembelajaran sosial-emosional dapat menjadi salah satu alternatif untuk meningkatkan hasil belajar peserta didik. Kelebihan dari pembelajaran sosial-emosional ini bukan hanya hasil belajar yang ditingkatkan, tetapi berbagai aspek lain pun dapat dipengaruhi secara signifikan. Pada penerapannya di sekolah, pembelajaran sosial-emosional ini dapat menggunakan program seperti Social Decision Making and Social Problem Solving (SDM/SPS) dan The Resolving Conflict Creatively Program (RCCP).
PERAN MEDIA SOSIAL TERHADAP PENGEMBANGAN MEDIA PEMBELAJARAN INOVATIF DI ERA SOCIETY 5.0
Authors: Hayati Early Ni’mah , Sukur Abdul , Nabila Alifian , Kusuma Arum Dyan , Amalia D. Adnindya , Aini Farida Nur , Hanafi Yusuf
Published: January 2025

Technology plays a significant role, one of which is in the field of education. Currently, we are entering the era of society 5.0, which is defined as a concept of learning centered on humans and technology. In the context of education, teachers can integrate technology into learning activities, one of which is through the role of social media. Therefore, the aim of this article is to understand the role of social media in the development of innovative learning media in the era of society 5.0. This article utilizes the literature review method. Literature review method involves searching, exploring, reading, and examining relevant literature related to the research through accountable sources. The results of this research show that the use of social media such as TikTok and YouTube can be used as learning references and also as media in creative and innovative learning activities.
PERAN LAYANAN BIMBINGAN KLASIKAL DENGAN METODE WINDOW SHOPPING TERHADAP PEMAHAMAN KONSEP DIRI PESERTA DIDIK KELAS XI SMK NEGERI 1 MALANG
Authors: Yulanda Melia
Published: January 2025

This research aims to determine the role of classical guidance services using the window shopping method in understanding the self-concept of class XI students at SMK Negeri 1 Malang. This research is qualitative research which produces descriptive data in the form of written words originating from the author's observations regarding the behavior of the subjects being observed. The data obtained in this research is data resulting from observations and open interviews with students. The subjects in this research were students of class XI Accounting 3 at SMK Negeri 1 Malang. The results of this research show that classical guidance services using the window shopping method for understanding the self-concept of class XI students at SMK Negeri 1 Malang have a good role in increasing students' understanding of the topics discussed. Thus, the use of innovative methods such as the window shopping method is very important to continue to be developed, especially in the implementation of guidance and counseling services so that students have a deep understanding of social problems and achieve optimal developmental tasks.
ANALISIS KEBUTUHAN IMPLEMENTASI PROJECT BASED LEARNING TERINTEGRASI CULTURALLY RESPONSIVE TEACHING PADA PENINGKATAN HASIL BELAJAR MATERI BIOTEKNOLOGI KONVENSIONAL
Authors: Zaldiana Aulia , Mulyati Yayuk
Published: January 2025

The aim of this research is to find solutions to improve student learning outcomes based on everyday cultural context problems. Various studies reveal that lacking problem solving skills will make learning less meaningful and result in low student learning outcomes. This is also known from the lack of student involvement due to monotonous learning activities so that students tend to get bored and bored. The method used is literature review and interviews aimed at teachers learning conventional biotechnology. Based on the literature review of interviews conducted, an ideal solution was obtained to solve this problem, namely the application of Project Based Learning with a Culturally Responsive Teaching approach to improving learning outcomes in Conventional Biotechnology. To be able to produce a product that is a solution, students start from a problem that refers to the context of cultural introduction, namely poisoning of tapai fermented processed products. Providing authentic project-based learning has an impact on developing internal motivation, creativity, a sense of responsibility, cooperation and problem solving abilities as a result of projects carried out to produce maximum results.
PENINGKATAN KETERAMPILAN ENTREPRENEURSHIP PESERTA DIDIK SEKALIGUS MENYOKONG TERWUJUDNYA LINGKUNGAN SEKOLAH ADIWIYATA MELALUI PROGRAM KREATIVITAS DAUR ULANG SAMPAH
Authors: Halim Moh. Kamal , Jariah Ainun , Ardianty Annida Elfiana Citra , Ronggopuro Burhanuddin , Indahsari Nita Dwi , Habiddin Habiddin
Published: January 2025

Waste poses a significant environmental threat, leading to the spread of diseases, water pollution, flooding, unpleasant odors, and general discomfort. Despite its negative impacts, waste holds immense economic potential. Recycling can transform waste into valuable resources, boosting the economy. This study analyzes the waste recycling creativity program at SMPN 7 Malang, examining its effectiveness in enhancing students' entrepreneurship skills and supporting the realization of the Adiwiyata School Environment. Employing a qualitative descriptive approach, data was collected through interviews, observations, and documentation. The findings reveal the successful implementation of the waste recycling creativity program at SMPN 7 Malang, demonstrating its positive impact on students' entrepreneurship skills. Students are trained to transform waste into marketable products, such as bags, pencil cases, wall decorations, and more. Additionally, the program contributes to the realization of the Adiwiyata School Environment by reducing waste in the school premises and students' neighborhoods.
PERENCANAAN PEMBELAJARAN TERINTEGRASI CULTURALLY RESPONSIVE TEACHING (CRT) DI SMP NEGERI 4 MALANG DAN SMP LABORATORIUM UM: PERSPEKTIF BERBASIS KARAKTERISTIK PESERTA DIDIK
Authors: Adiningsih Aisyah , Ayaturrahman Annisa’ , Maulida Anisa , Nurvitarini Dita Mei , Silma Yuda , Widyartono Didin
Published: January 2025

The aim of this article is to provide a comprehensive review of integrated lesson planning with a Culturally Responsive Teaching (CRT) approach at SMP Negeri 4 Malang and SMP Laboratorium UM. This study employs a descriptive-comparative approach to compare lesson planning strategies between the two schools, focusing on how the planning considers the needs and characteristics of the students. Data were collected through classroom observations, tests, interviews with teachers, and reviews of lesson planning documents. In-depth analysis of the data reveals differences and similarities in the implementation of CRT at each school, as well as its implications for enhancing the success of learning relevant to the students' cultural contexts.
Analisis Efektivitas Penggunaan Quizizz terhadap Motivasi Belajar PAI Siswa SD
Authors: Sudarsono Ahmad , Nurmalia Nurmalia , Adelia Aprilla , Rahmawati Lili , Syahputra Farid Ilham
Published: January 2025

Pendidikan di Indonesia berkembang cukup pesat seiring dengan perkembangan zaman. Pendidikan agama menjadi landasan utama bagi peserta didik sehingga mereka dapat menjalankan kehidupan sesuai dengan pedoman ajaran agama yang dianut. Pada pelajaran agama Islam di tingkat 2 dasar kurangnya tingkat motivasi belajar pada peserta didik menjadi salah satu aspek yang menghambat munculnya karakter kuat dalam jiwa peserta didik, oleh karenanya penerapan media pembelajaran yang inovatif sangat penting dalam menumbuhkan rasa keingintahuan peserta didik sehingga dapat menimbulkan motivasi belajar peserta didik pada mata pelajaran pendidikan agama Islam. Penelitian ini bertujuan untuk mencari tahu berada ditingkat mana keefektivitasan media pembelajaran interaktif berbasis Quizizz terhadap motivasi belajar peserta didik dalam mata pelajaran pendidikan agama Islam. Penelitian ini menggunakan metode studi literatur dengan tahapan awal mencari permasalahan dan menginternalisasikannya dalam penelitian, data-data terkait penelitian pada di kumpulkan dari berbagai sumber, seperti artikel, jurnal, skripsi maupun buku yang memiliki keterkaitan dengan penelitian, hal ini dilakukan untuk lebih memperkuat hipotesis yang berkaitan dengan penelitian. Pada penelitian ini menghasilkan beberapa data sebagai berikut: 1). Media interaktif berbasis Quizizz dapat meningkatkan motivasi siswa pada proses pembelajaran, 2). Pembelajaran menggunakan media interaktif berbasis quizizz mampu membuat siswa lebih bersemangat dalam belajar, 3). Media interaktif berbasis Quizizz sangat di bermanfaat dalam proses pembelajaran karena membantu guru agar lebih mudah saat menyampaikan materi sehingga pembelajaran tidak monoton.
Developing RENATAMA (Reyog Kendang & Etnomathematics) Based on Digital Board Game with Cognitive Psychology Content to Improve Numeracy Literacy
Authors: Dirgantoro Ajar , Purwananti Yepi Sedya , Hartanto Setyo
Published: January 2025

Mathematical literacy plays an important role in using mathematics to solve real problems. Based on the PISA results, Indonesia's mathematical literacy is currently ranked in the bottom 15, although in general it has increased compared to the previous year. This is in line with the results of the Minimum Competency Assessment in Tulungagung Regency which shows that numeracy literacy skills are still low. This research aims to: (1) to develop an android application as a learning media in the form of digital board game based on PBL with cognitive psychology content to improve Numeracy Literacy, and (2) to know the feasibility level of the android application as a learning media based on digital board game based on PBL with cognitive psychology content to improve Numeracy Literacy. The application is collaborated with the local cultural content of Reyog Kendang and is acronymised RENATAMA. This research uses the Research and Development (R&D) method using the ADDIE development model.  The research subjects included 1 media expert, 1 material expert, and seventh grade students at SMPN 1 Sumbergempol and SMPN 3 Tulungagung. The data collected in the form of qualitative data in the form of interview results and quantitative data in the form of a percentage of feasibility test results. The questionnaire used in this study has aspects that are in accordance with the ISO / IEC 9126 model. The results of this study, show: (1) the RENATAMA (Reyog Kendang & Etnomathematics) based on Digital Board Game with Cognitive Psychology content to improve Numeracy Literacy, and (2) the developed application is declared feasible to use. Feasibility is obtained from the results of the feasibility test with details: (1) Media experts with a percentage of 91.5%; (2) Material experts with a percentage of 96%; (3) Small group test of 88.8%; and (4. Large group test with a percentage of 89%. From the results of this study, it can be categorized as ‘Very Feasible’. So, the android application that has been developed is very feasible to use as a learning media. The advantages are through the use of technology compared to conventional ethnomathematics, originality, adoption of assets and integrated content of culture with mathematics, partnership with regular evaluation, involvement of lecturers and students to encourage the achievement of IKU-PT and being able to motivate themselves according to the goal of increasing numeracy literacy. The novelty is in combining cultural exploration of reyog kendang and PBL-based mathematics with a cognitive psychology approach to improve numeracy literacy, as well as pride in local culture through the RENATAMA.
Understanding TikTok Users : How FoMO and TikTok Engagement Affect Self-Control
Authors: Maharani Gita , Kholidin Farid Imam , Prasetia Agung Tri
Published: January 2025

Currently, technological developments are widely used by people to help their daily activities. With the development of technology, social media is also developing among people, both young and old. This study aims to solve the phenomenon of FoMO problems and the intensity of TikTok use on self-control in adolescents in Sungai Penuh Village. Therefore, the study can be said to be unique from previous studies because, first, this study adds a new variable, namely FoMO, which is continuous with the variable of the intensity of TikTok use and self-control and has not been researched by previous research, the second can support parents in supervision and help adolescents manage their daily time effectively. The research method chosen is the Survey Research method using a descriptive quantitative approach. The sample used in this study focused on adolescents in Sungai penuh village, but the size of this sample had to be adjusted to the purposive sampling technique. FoMO (Fear of Missing Out) and the intensity of TikTok use indirectly have a significant effect on adolescent self-control in Sungai Penuh village, Indonesia.
Abordaje del Ciberbullying y Grooming en adolescentes mexicanos: Una revisión sistemática de la literatura
Authors: Sánchez-Domínguez Juan Pablo , Magaña Raymundo Luis
Published: January 2025

Given the lack of systematic reviews in Mexico that explore the phenomena of Cyberbullying and Grooming, types of digital violence that mainly affect children and adolescents, this research was conducted with the aim of identifying the approach that has been given to the phenomenon within the country between 2000-2022. The PRISMA method was used and publications indexed in the Open Access databases SciELO, Redalyc, Dialnet, ScienceDirect and PubMed were consulted.  Thirty-five studies were analyzed between 2000-2022, finding a high prevalence of quantitative works that mainly explore the nature and dynamics of Cyberbullying; most of the studies are concentrated in the center-north of the country, with more than two authors per article. The almost null research on Grooming in Mexico stands out, as well as studies on validation of instruments and intervention programs against Cyberbullying; in future reviews it is suggested to explore non-indexed sources that broaden the scope that has been had of the phenomenon.
Influencia de la educación y la consejería en la lactancia materna exclusiva
Authors: Sanclemente Ayala Luis Fernando , Avellaneda Catalina
Published: January 2025

El objetivo se centró en indagar alrededor de la influencia de la educación y la consejería en LME en mujeres en período de lactancia. Se desarrolló bajo el uso de la investigación cualitativa de tipo inductiva, con una aproximación a la fenomenología, mediante la técnica de entrevista semiestructurada; la población se conformó por diecisiete mujeres en período de lactancia, madres de niños y niñas entre 0 a 2 años de edad, atendidos en el servicio de crecimiento y desarrollo de la ESE Suroriente, IPS Pública ubicada de la ciudad de Cali Colombia, para el año 2022, la indagación se realizó mediante el uso de la estrategia “bola de nieve” hasta la saturación de resultados y variables emergentes.
Se implementó un instrumento codificado para la entrevista semiestructurada que contenía nueve preguntas, al cual se le realizó una prueba piloto, con el fin de recopilar información relacionada con: los conocimientos previos alrededor de lactancia materna, el acceso a la información, las dificultades alrededor de dar de amamantar y el acceso a la consejería brindada por parte de profesionales en salud de la institución. Una vez realizadas las entrevistas se codificaron las mismas para garantizar el principio de confidencialidad durante el proceso de sistematización y análisis; así mismo, se procedió a la transcripción de las entrevistas y a desarrollar el análisis de contenido con base en las categorías y categorías emergentes. Se pudo obtener que tanto la educación como la consejería, aunque son implementadas por la institución prestadora del servicio de salud, no se están llevando a cabo como se espera.
Patient-centric innovations in pain management for postoperative care
Authors: Abdullah Almottowa Hisham , Seraj Abdurrahman Sami , Darwish Hasan Jasim , Khubyah Shahad Yahya , Jan Rami Hassan , Hanbashi Adil Ibrahim , Almutair Rawan Khalid , Salman Husain Hasan , Alghamdi Abdullatif Mohammad , Altawil Faisal Wajih , Naser Hussain Jaffer
Published: January 2025

Advancements in postoperative pain management have shifted toward patient-centric approaches, focusing on personalization, multimodal strategies, and the integration of technology. These innovations aim to enhance recovery outcomes, minimize opioid reliance, and address individual patient needs. Technological tools, such as patient-controlled analgesia (PCA) systems and artificial intelligence (AI)-driven predictive models, optimize pain control by enabling real-time monitoring and tailored interventions. Wearable devices and remote health applications further extend care beyond clinical settings, fostering better communication between patients and providers. Multimodal strategies have emerged as pivotal in postoperative recovery, combining pharmacological and non-pharmacological methods to achieve synergistic benefits. Regional anesthesia, prehabilitation programs, and the use of opioid-sparing medications demonstrate significant efficacy in reducing complications and promoting early mobility. The psychological dimensions of pain management, addressed through therapies like cognitive-behavioral interventions, play an integral role in holistic care, particularly for high-risk populations. Barriers such as socioeconomic inequities, educational limitations, and regulatory challenges hinder widespread adoption of these advancements. Disparities in access to innovative treatments exacerbate healthcare inequalities, while gaps in training impede the integration of interdisciplinary approaches. Stigma surrounding pain management, coupled with concerns over opioid misuse, further complicates implementation. Future directions include leveraging AI and machine learning for developing adaptive pain management frameworks, enhancing patient outcomes through precision medicine. Collaborative efforts among stakeholders, including policymakers, healthcare providers, and researchers, are essential for addressing these challenges. Bridging current gaps will require global harmonization of regulatory standards, equitable distribution of resources, and robust public health initiatives to reshape societal perceptions of pain management. As innovations continue to evolve, they hold the potential to revolutionize postoperative care by prioritizing personalization, equity, and patient empowerment.
Influence of occlusal loading on the longevity of dental bridges
Authors: Aqely Mona A. , Faraj Mayyada I. , Alnafisi Aasaiel A. , Ayoub Mohammed N. , Diqini Ibrahim M. , Majrashi Nawal M. , Alajam Ismail A. , Alsheri Aisha M. , Alrayes Nouf A. , Alahmari Haitham A. , Alghabban Abdulmohsen S.
Published: January 2025

Dental bridges are a cornerstone in restorative dentistry, offering functional and aesthetic solutions for patients with missing teeth. Their longevity is influenced by a complex interplay of biomechanical, material, and clinical factors. Occlusal loading, the force exerted during mastication and other functional activities, plays a critical role in determining the durability of these prostheses. Excessive or uneven occlusal forces can lead to mechanical failures such as fractures, debonding, or material fatigue. Advances in materials, particularly high-strength ceramics like zirconia, have improved the ability of bridges to withstand these stresses, providing enhanced resistance to wear and fracture. Design considerations, including connector dimensions and the use of computer-aided design and computer-aided manufacturing (CAD/CAM) technology, ensure more precise stress distribution, minimizing the risk of localized mechanical failures. Finite element analysis and digital occlusal analysis have further refined the understanding of stress patterns, enabling personalized approaches tailored to individual patient needs. Clinical studies have highlighted the importance of maintenance strategies, such as regular follow-ups and early repair of minor defects, in extending the lifespan of dental bridges. Patient-specific factors, such as parafunctional habits and periodontal health, significantly influence outcomes and necessitate individualized treatment planning. Emerging technologies, combined with material innovations, have shifted the focus toward optimizing the biomechanical performance of dental bridges. Trends reveal that integrating robust materials with advanced design techniques results in improved longevity and reduced failure rates. The interplay between clinical, material, and mechanical factors continues to evolve, offering new insights into enhancing the reliability and success of dental bridges over time.
Evidence-based preventive care guidelines in pediatric primary care
Authors: Alzanbagi Salah Mohammed , Ismael Mohammed Zuhair , Alshehri Hassan Saud , Almalki Ohood Mohammed , Julaidan Banan Mohammed , Miralam Raed Talat , Eshan Adeel Ibrahim , Khalifah Reem Malak , Dawshi Tahani Abdullah , Hawsawi Ashraf Omar , Aljohani Mohammed Saud , Babonji Mohammed , Alradha Abdulaziz
Published: January 2025

Evidence-based preventive care guidelines offer a systematic approach to early detection, prompt intervention, and the promotion of health, encompassing various aspects of physical, mental, and developmental well-being. Recently, more focus has been placed on improving guidelines for preventive interventions for pediatric populations. Primary care is considered a great venue for implementing these preventive interventions. In addition, primary care is the preferable place for parents to do such preventive interventions. Multiple authorized organizations have developed new guidelines and recommendations in order to improve the delivery of preventive measures in pediatric primary care in recent years. Unlike adults’ guidelines, pediatric preventive guidelines are confusing and of low quality, leading to more challenges faced by primary care providers. This review aimed to evaluate the quality of recent studies on this topic, with a focus on the accuracy and efficacy of current evidence-based guidelines. Despite advancements, challenges such as childhood obesity, speech disorders, and depression require further refinement of evidence-based guidelines, supported by high-quality research. Additionally, the integration of technology has demonstrated potential for enhancing the delivery and outcomes of pediatric primary care.
Evaluating the effectiveness of enhanced recovery after surgery protocols on outcomes in general surgery: a systematic review
Authors: Aljubouri Salman A. , Alsaedi Emad A. , Alrehaili Meaad A. , Aloufi Hussam K. , Alsubhi Reham M. , Aljayyar Mohammed W. , Seraj Abdurrahman S. , Samman Hasan M. , Alharbi Amal N. , Kaki Waleed K. , Mohammad Heba A. , Alharbi Nawaf H. , Almarwani Mohammed N.
Published: January 2025

Multimodal treatment pathways called enhanced recovery after surgery (ERAS) programs are intended to lessen surgery's physical and emotional impacts. In many surgeries, patient outcomes are linked to better compliance with ERAS protocols. To investigate the effectiveness of ERAS protocols on outcomes in general surgery. The systematic review used PubMed, Scopus, Google Scholar, and Clinicaltrial.gov as data sources. Randomised clinical trials comparing any traditional protocol with ERAS. Protocols for general surgical procedures, published from January 2015 to January 2025, were included based on preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. A total of 1860 study titles were identified. Only randomised control trials were included, so 230 titles were produced as randomized controlled trial (RCT). Researchers chose 145 abstracts for screening after removing the papers that did not fit the original search criteria; only 13 qualified for final review. Three reviewers independently identified the relevant trials and extracted data on study details, outcomes, and efficacy from included studies. The overall hospital stay, pain score, medical cost, post-operative complications, morbidity, and inflammation were significantly reduced in the ERAS group (p<0.05), and improved quality of life, comfort level, and immunity. The study concluded that ERAS protocol helps to improve patient well-being after surgery and should be implemented in general surgery. Further longitudinal studies should also be conducted.
Adverse effects of antinutrients on human health: a systematic review
Authors: Tiwari Divyanshi , Dubey Dharmendra Kumar
Published: January 2025

Antinutrients are naturally occurring compounds found in various foods that can interfere with the absorption or utilization of nutrients in the body. There are many studies about various antinutrients and or on some particular antinutrients. The aim of our systematic review is to provide wholesome information about most of the antinutrients. Many plants and vegetables contain a variety of harmful compounds (cyanide, nitrate, phenols, etc.) and anti-nutrients (phytate, oxalate, etc.). The detrimental effects on the absorption of minerals and micronutrients in diet are caused by anti-nutrients. Chemicals known as "anti-nutrients" lower the body's ability to use certain nutrients, including proteins, vitamins, and minerals. This prevents the nutrients in food from being used to their full potential and lowers the meal's nutritional value. A systematic search was done using various search engines like Google Scholar, PubMed, science direct. Database was collected between the years of 2010 to 2023 for the English literature using different keywords like antinutrients, lectins, phytates. A total number of 80 articles selected during search out of them 15 studies were taken after screening in the review with experimental and non-experimental study design. Our study suggests that we can reduce the antinutrient content in food by different methods like soaking, fermentation, boiling, and washing.
Co-occurrence of Phelan-McDermid syndrome and metachromatic leukodystrophy
Authors: Mallakmir Snehal , Chandrasekaran Anbukayalvizhi , Phelan Kety , Merchant Rashid , Patil Shekhar
Published: January 2025

Very few cases have been described so far with co-occurrence of Phelan-McDermid syndrome (PMS) and metachromatic leukodystrophy (MLD). Those patients harbour a chromosome (chr) 22q13deletion encompassing at least the SHANK3 and ARSA genes and a pathogenic variant in the arylsulfatase A (ARSA) gene residing on the other allele. The deletion in chr22q13 results in PMS phenotype and the presence of pathogenic variation on the other intact copy of ARSA gene, leads to MLD phenotype due to biallelic loss of ARSA function. We describe a male infant, born to a third-degree consanguineous couple, who exhibited neuroregression at the age of 8 months, presented with developmental delay, hypotonia which rapidly progressed to feeding difficulties, axial hypotonia, ptosis, sleep disturbance, dystonia, spasticity, and abnormal eye movements. Brain MRI showed T2 hyperintensities consistent with MLD. Biochemical workup showed deficiency of ARSA enzyme activity. Genetic investigations revealed heterozygous deletion of size 2.5 Mb on chr 22q13.3 encompassing the entire ARSA gene and a pathogenic variant in the other copy of ARSA gene. Parents and sibling were tested and informed about the disease management and genetic testing in extended family members to understand the risk and preventive measures. Few case reports have proposed screening for urine sulfatides levels at the time of PMS diagnosis to identify pre-symptomatic or asymptomatic MLD patients to facilitate management and our case supports this proposal.
Short femur on antenatal ultrasound reveals chondrodysplasia in two twins: a case report
Authors: Mohamed Khaoula B. , Medemagh Malak , Mohamed Chayma C. , Fekih Ichrak B. , Mhiri Karima , Toumi Dhekra , Zoukar Olfa
Published: January 2025

Chondrodysplasia is a rare autosomal recessive disorder with diverse clinical manifestations, including rhizomelic short limbs, facial anomalies such as a broad nasal bridge, epicanthus, dysplastic ears, and micrognathia. While mental impairment is uncommon, spasticity and seizures may occur. The fetal prognosis is generally favorable in the absence of additional malformations. In cases with a family history of chondrodysplasia, early morphological assessment, especially of the limbs during the first trimester, is crucial for identifying suggestive ultrasound signs. We present a rare case of chondrodysplasia in a twin pregnancy in a multiparous woman. This case underscores the importance of antenatal diagnosis and comprehensive genetic counselling to reduce the risk of transmission to future generations.
Responsabilidad penal de las personas jurídicas: Reformas al COIP del 2021 vs. Principio de proporcionalidad
Authors: Beltrán Ruiz Dayana Lizeth
Published: January 2025

Con la reforma del año 2021, el COIP implementó un sistema exclusivo de circunstancias modificativas de la responsabilidad, es decir, circunstancias atenuantes y agravantes dentro de la responsabilidad penal de las personas jurídicas. Pero al no existir un mecanismo específico de aplicación para esta nueva herramienta, se remitió a la regla general de aumento o reducción de las penas por tercios. En este contexto, la investigación aborda la relación que existe entre las penas modulables e inmodulables de las personas jurídicas y los principios de proporcionalidad y determinación de la pena. De esta manera, se encontró que la mayoría de las penas previstas para las personas jurídicas son de carácter inmodulable, lo cual impide su aumento o reducción conforme la regla general, violentando directamente la proporcionalidad.
Comparative assessment of approaches to training bachelor's stu-dents in aircraft engine design
Authors:   Ufa University of Science and Technology (UUST), Ufa, Russia, Gvozdev V.E. , Galimov R.R. ,   Federal State Enterprise "AVANGARD", Sterlitamak, Republic of Bashkortostan, Russia, Bezhaeva O.Ya. ,   Ufa University of Science and Technology (UUST), Ufa, Russia, Timofeeva K.Yu. ,   Ufa University of Science and Technology (UUST), Ufa, Russia
Published: January 2025

The findings presented in this paper rely on system archetypes, which serve as unified conceptual models for addressing organizational challenges in managing complex systems. These archetypes facilitate the creation of comparable de-scriptions of problem situations by accommodating differing perspectives of stakeholders (actors) on the factors hin-dering the integration of local systems. The research framework integrates system archetypes with the House of Quality model and employs correlation coefficients—rank, partial, and multiple. An example of multi-faceted modeling is pro-vided, wherein the calculated correlation coefficients act as indicators of the degree of alignment in actors' views re-garding the factors of the problem situation. Multiple correlation coefficients are interpreted as measures of the con-sistency of an individual actor’s opinions with those of the collective group, while partial correlation coefficients gauge the alignment of opinions between specific pairs of actors. The proposed methodology for quantitatively assessing the alignment of heterogeneous actors' perspectives enables the evaluation of the effectiveness of initiatives aimed at building a communication framework that supports the development of a shared understanding of the significance of various factors in a problem situation.
Conceptual and notional analysis: a general approach
Authors:   Moscow Institute of Physics and Technology, Dolgoprudny, Russia, Vykhovanets V.S.
Published: January 2025

The paper suggests distinguishing between the methodologies of conceptual analysis and notional analysis. The differ-ence lies in how the notion and concept are interpreted. In the paper, a notion is viewed as an individual opinion or un-derstanding of something, whereas a concept represents a general notion or abstract idea. It is assumed that many simi-lar concepts exist with varying scopes and contents. A concept is treated as an objectified notion developed and solidi-fied through social experience. The primary representation of the results of established conceptual analysis methods is shown to be a semantic network, where the vertices are concepts and the arcs represent relationships between them. However, it is noted that classical set theory and semantic networks are insufficient to formalize notions and concepts; instead, the theory of structures must be employed. Conceptual analysis is described as a technique for synthesizing formal concept descriptions using Boolean and Cartesian construction operations. The challenges of applying concep-tual analysis within the framework of the theory of structures are outlined. The development of notional analysis is linked to the demand for precise, unambiguous, and consistent notion descriptions, driven by the variability of their properties. Notional analysis is defined as a method for formal normal descriptions using generalization and associa-tion operations. Generalization entails combining notions such that the entities of the generalized notions become enti-ties of the resulting notion. Association involves merging notions, with each entity of the resulting notion including one entity from each of the associated notions. Notional analysis addresses issues encountered when describing concepts using a corpus-based approach by generating diverse descriptions of notions. It is demonstrated that both conceptual and notional analyses are rooted in the theory of structures. The paper identifies areas where these analyses are effec-tively applied and provides an example of using notional analysis in the design of a technical device.
Building a knowledge graph from telecommunication data
Authors:   Saint Petersburg Electrotechnical University «LETI» (ETU «LETI»), Saint-Petersburg, Russia, Golovin A.A. , Zhukova N.A. ,   Saint Petersburg Electrotechnical University «LETI» (ETU «LETI»), Saint-Petersburg, Russia,   St. Petersburg Federal Research Centre of the Russian Academy of Sciences (SPCRAS), Saint-Petersburg, Russia
Published: January 2025

The paper presents a method for building a knowledge graph from telecommunication data using proprietary and ref-erence models commonly employed in the telecommunications domain. Reference models are based on those included in the framework developed by the TM Forum consortium. The proposed approach involves building a knowledge graph for proprietary models through automated processing of autotest log files and billing system database tables. The relevance of knowledge graphs stems from their structured and semantic nature, as well as their potential for applying machine learning algorithms to generate recommendations for optimizing telecommunication processes and systems. A method based on a multi-step reasoning approach is proposed for creating interpretable recommendations by predict-ing and restoring missing links in a proprietary knowledge graph. This approach treats multi-step reasoning as a ques-tion-answering task using natural language processing techniques. The implementation of the proposed solution, lever-aging a transformer-based neural network architecture, yielded interpretable results while maintaining metric values comparable to existing methods.
A method for developing intelligent simulators based on ontology of the subject domain
Authors:   Volgograd State Technical University (VolSU), Volgograd, Russia, Sychev O.A. , Penskoy N.A. ,   Volgograd State Technical University (VolSU), Volgograd, Russia, Terekhov G.V. ,   Volgograd State Technical University (VolSU), Volgograd, Russia
Published: January 2025

In academic disciplines, students are required to learn many new concepts, which necessitates extensive training with feedback. An intelligent simulator enables students to practice solving simple problems while receiving explanations for their mistakes, allowing teachers to focus on addressing more complex issues during lessons. This paper presents a method for developing intelligent simulators based on the ontology of the subject domain, implemented as web appli-cations suitable for both classroom and extracurricular use. Representing the problem and the subject area model in RDF format enables logical inference using the Apache Jena Reasoner inference engine. An example is provided of an intelligent simulator designed for learning the order of operations in expressions, supporting the C++, C#, and Python programming languages. The simulator can explain errors, generate explanatory hints, and engage in educational dia-logue through guiding questions. The simulator was tested with undergraduate and graduate students of the Faculty of Electronics and Computer Engineering at Volgograd State Technical University. Most students found the simulator to be more useful than traditional training tests. It can be employed both for independent study and as part of the educa-tional process in classroom settings.
How are Students Really Selected for a PhD? The Impact of the Thesis and Solving the Country's Problems
Authors: Akhondzadeh Shahin
Published: January 2025

The Article Abstract is not available.
Moringa oleifera Docking to Estrogen Receptor α Ameliorates Placental and Brain Damage in Stressed Rats
Authors: Chukwu Odochi O. , Iyare Cordilia , Ezimah Anthony C.U. , Okorocha Albert E. , Konyefom Nwaeze G. , T. Asogwa Nnaemeka , Igwe Nancy P.
Published: January 2025

Background: Stress during pregnancy significantly impacts offspring early physiological programming. Herbal remedies are frequently used by pregnant women to enhance their wellbeing. Moringa oleifera Leaf Extract (MoLE) is believed to have both anti-stress and antioxidant properties which can act as a Selective Estrogen Receptor Modulator (SERM) that regulate activities of estrogen, and can have different effects on different tissues. Goal of this study is to compile information on molecular docking analysis of phytochemicals found in MoLE targeting Estrogen Receptor-alpha (ER-α) and assess effects of MoLE administration on dam's and fetal brain tissues and placenta, during gestational stress.
Methods: Phytochemical study of MoLE was determined using Gas Chromatography-Mass Spectrometry. Molecular docking technique was employed to predict aspects of interaction and binding affinities energy of bioactive phytocompounds in protein site of ER-α using autodock tools. 30 apparently healthy pregnant Albino-Wistar rats were randomly placed into 6 groups of 5 rats per group and exposed to Chronic Unpredictable Stress (CUS) protocol for two weeks, as follows: Group I (water and normal rat chow ad libitum), Group II (CUS protocol only), Group III (5 mg/kg body weight/day of MoLE), Group IV (10 mg/kg body weight/day of MoLE), Group V (CUS protocol +5 mg/kg body weight/day of MoLE), Group VI (CUS protocol +10 mg/kg body weight/ day of MoLE).
Results: This study found that 1-Propanol, 3,3'-oxy bis- and 1, 2, 3-Trimethyldiazir-idine are most potent ligands for ER-α among all 41 compounds. Photomicrograph examination of tissues from stressed rats showed mild to severe alterations in histology. Consumption of MoLE during chronic stress showed mild to moderate protective effects.
Conclusion: These findings suggest that 1-Propanol, 3,3'-oxy bis- and 1, 2, 3-Trimethy-ldiaziridine can be further investigated for development of novel therapeutics.
The Induction of L-lysine-α-Oxidase from Trichoderma Harzianum Rifai by Metabolic Products of Brevibacterium sp. and the Improvement of Its Isolation and Purification Techniques
Authors: Smirnova Irina , Neborak Ekaterina , Shkinev Valeriy , Larichev Victor , Shneyder Yuri , Bashkirova Ida , Karimova Elena , Gavrilyuk Lyudmila , Baranova Daria , Ploskonos Maria
Published: January 2025

Background: The enzyme L-lysine-α-oxidase from Trichoderma harzianum Rifai is a promising anticancer, antifungal and antibacterial agent. Intensive exploring of its physico-chemical properties and possible ways of application requires sufficient amounts of the protein which in turn depends on good techniques of cultivation of the micro-organism producer, enzyme soft isolation and purification, and storage.
Methods: An improved method has been suggested for isolation and purification of the enzyme. A specific combination of column sorbents was adapted and gradient elution with sodium chloride was applied to elevate the yield of the enzyme. The inductive influence of Metabolic Products (MP) of the Brevibacterium species, along with fungal metabolites of Ulocladium sp. and Trichoderma sp. was tested. The enzyme activity assay was based on the detection of oxidized dimethylbenzidine in a peroxidase reaction coupled with an L-lysine-α-oxidase reaction. Some enzyme properties were additionally explored.
Results: The upgraded technique of isolation and purification resulted in a yield of enzyme of about 79%. All strains of Brevibacterium sp. proved to be potent enhancers of L-lysine-α-oxidase activity and concomitant activities. The induced enzyme appeared to be less specific but more thermostable. Possible application scopes for the enzyme with modified properties are discussed. Phosphate buffer solution (pH=5.6) appeared to be the best one for long-term storage of the enzyme.
Conclusion: A significant inducing effect of MP of Brevibacterium sp. on L-lysine-α-oxidase has been detected, and its isolation and purification techniques have been improved.