bluuebunny/crossref_metadata_2025 huggingface dataset:
High-resolution metabolomic biomarkers for lung cancer diagnosis and prognosis
Authors: Qi Shi-ang , Wu Qian , Chen Zhenpu , Zhang Wei , Zhou Yongchun , Mao Kaining , Li Jia , Li Yuanyuan , Chen Jie , Huang Youguang , Huang Yunchao
Published: June 2021

Lung cancer is the leading cause of human cancer mortality due to the lack of early diagnosis technology. The low-dose computed tomography scan (LDCT) is one of the main techniques to screen cancers. However, LDCT still has a risk of radiation exposure and it is not suitable for the general public. In this study, plasma metabolic profiles of lung cancer were performed using a comprehensive metabolomic method with different liquid chromatography methods coupled with a Q-Exactive high-resolution mass spectrometer. Metabolites with different polarities (amino acids, fatty acids, and acylcarnitines) can be detected and identified as differential metabolites of lung cancer in small volumes of plasma. Logistic regression models were further developed to identify cancer stages and types using those significant biomarkers. Using the Variable Importance in Projection (VIP) and the area under the curve (AUC) scores, we have successfully identified the top 5, 10, and 20 metabolites that can be used to differentiate lung cancer stages and types. The discrimination accuracy and AUC score can be as high as 0.829 and 0.869 using the five most significant metabolites. This study demonstrated that using 5 + metabolites (Palmitic acid, Heptadecanoic acid, 4-Oxoproline, Tridecanoic acid, Ornithine, and etc.) has the potential for early lung cancer screening. This finding is useful for transferring the diagnostic technology onto a point-of-care device for lung cancer diagnosis and prognosis.
Author Correction: MiR218 Modulates Wnt Signaling in Mouse Cardiac Stem Cells by Promoting Proliferation and Inhibiting Differentiation through a Positive Feedback Loop
Authors: Wang Yongshun , Liu Jingjin , Cui Jinjin , Sun Meng , Du Wenjuan , Chen Tao , Ming Xing , Zhang Lulu , Tian Jiangtian , Li Ji , Yin Li , Liu Fang , Pu Zhongyue , Lv Bo , Hou Jingbo , Yu Bo
Published: June 2021

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Osmotic stress and vesiculation as key mechanisms controlling bacterial sensitivity and resistance to TiO2 nanoparticles
Authors: Pagnout Christophe , Razafitianamaharavo Angelina , Sohm Bénédicte , Caillet Céline , Beaussart Audrey , Delatour Eva , Bihannic Isabelle , Offroy Marc , Duval Jérôme F. L.
Published: June 2021

Toxicity mechanisms of metal oxide nanoparticles towards bacteria and underlying roles of membrane composition are still debated. Herein, the response of lipopolysaccharide-truncated Escherichia coli K12 mutants to TiO2 nanoparticles (TiO2NPs, exposure in dark) is addressed at the molecular, single cell, and population levels by transcriptomics, fluorescence assays, cell nanomechanics and electrohydrodynamics. We show that outer core-free lipopolysaccharides featuring intact inner core increase cell sensitivity to TiO2NPs. TiO2NPs operate as membrane strippers, which induce osmotic stress, inactivate cell osmoregulation and initiate lipid peroxidation, which ultimately leads to genesis of membrane vesicles. In itself, truncation of lipopolysaccharide inner core triggers membrane permeabilization/depolarization, lipid peroxidation and hypervesiculation. In turn, it favors the regulation of TiO2NP-mediated changes in cell Turgor stress and leads to efficient vesicle-facilitated release of damaged membrane components. Remarkably, vesicles further act as electrostatic baits for TiO2NPs, thereby mitigating TiO2NPs toxicity. Altogether, we highlight antagonistic lipopolysaccharide-dependent bacterial responses to nanoparticles and we show that the destabilized membrane can generate unexpected resistance phenotype.
Arctic open-water periods are projected to lengthen dramatically by 2100
Authors: Crawford Alex , Stroeve Julienne , Smith Abigail , Jahn Alexandra
Published: June 2021

The shrinking of Arctic-wide September sea ice extent is often cited as an indicator of modern climate change; however, the timing of seasonal sea ice retreat/advance and the length of the open-water period are often more relevant to stakeholders working at regional and local scales. Here we highlight changes in regional open-water periods at multiple warming thresholds. We show that, in the latest generation of models from the Coupled Model Intercomparison Project (CMIP6), the open-water period lengthens by 63 days on average with 2 °C of global warming above the 1850-1900 average, and by over 90 days in several Arctic seas. Nearly the entire Arctic, including the Transpolar Sea Route, has at least 3 months of open water per year with 3.5 °C warming, and at least 6 months with 5 °C warming. Model bias compared to satellite data suggests that even such dramatic projections may be conservative.
Metal–ligand cooperative κ1-N-pyrazolate Cp*RhIII-catalysts for dehydrogenation of dimethylamine-borane at room temperature
Authors: Pal Shrinwantu , Iwasaki Takanori , Nozaki Kyoko
Published: June 2021

3,5-Dimethylpyrazole (Pz*H) in well-defined Cp*RhIII (Cp* = 1,2,3,4,5-pentamethylcyclopentadienyl) complexes, or as an additive to [Cp*RhCl2]2 enhances catalytic activity in the dehydrogenation of dimethylamine-borane (DMAB) at room-temperature.
Start-up of bench-scale biofilters for manganese removal under tropical conditions: a comparative study using virgin pumice, silica sand, and anthracite filter media
Authors: Araya-Obando José A. , Rietveld Luuk C. , Quesada-González Andrea , Caballero-Chavarría Andrey , Pacini Virginia , Romero-Esquivel Luis G.
Published: June 2021

The suitability of biofiltration for Mn removal was confirmed under tropical conditions. The similarity in the performance of pumice with the other media confirmed its suitability for biological Mn removal.
A comprehensive review of adsorbents for fluoride removal from water: performance, water quality assessment and mechanism
Authors: Gai Wei-Zhuo , Deng Zhen-Yan
Published: June 2021

This review gives a comprehensive summary of various defluoridation adsorbents in terms of performance, water quality assessment and mechanisms.
Correction: Photocatalyzed redox-neutral decarboxylative alkylation of heteroaryl methanamines
Authors: Niu Pengfei , Yang Jingya , Yuan Yong , Zhang Yongxin , Zhou Chenxing , Bao Xiazhen , Huo Congde
Published: June 2021

Correction for ‘Photocatalyzed redox-neutral decarboxylative alkylation of heteroaryl methanamines’ by Pengfei Niu et al., Green Chem., 2021, 23, 774–779, DOI: 10.1039/D0GC04094K.
Correction: Ring-contraction of hantzsch esters and their derivatives to pyrroles via electrochemical extrusion of ethyl acetate out of aromatic rings
Authors: Liu Xu , Liu Chang , Cheng Xu
Published: June 2021

Correction for ‘Ring-contraction of hantzsch esters and their derivatives to pyrroles via electrochemical extrusion of ethyl acetate out of aromatic rings’ by Xu Liu et al., Green Chem., 2021, 23, 3468–3473, DOI: 10.1039/D1GC00487E.
Single and bi-excitonic characteristics of ligand-modified silicon nanoparticles as demonstrated via single particle photon statistics and plasmonic effects
Authors: So Woong Young , Abbas Sikandar , Li Qi , Jin Rongchao , Peteanu Linda A.
Published: June 2021

Silicon nanoparticles (Si NPs) exhibit bright single-quantum-state emission from the ligand-surface states and bi-excitonic emission from the particle core.
Diastereoselective synthesis of chiral 3-substituted isoindolinonesviarhodium(iii)-catalyzed oxidative C–H olefination/annulation
Authors: Li Xue-Hong , Gong Jun-Fang , Song Mao-Ping
Published: June 2021

A new method for the direct and stereoselective synthesis of chiral 3-substituted isoindolinones has been developed. Separation of the diastereoisomers and further transformations provide some important chiral isoindolinones.
Tubular supramolecular alternating copolymers fabricated by cyclic peptide–polymer conjugates
Authors: Song Qiao , Kerr Andrew , Yang Jie , Hall Stephen C. L. , Perrier Sébastien
Published: June 2021

Tubular supramolecular alternating copolymers using cyclic peptide–polymer conjugates are synthesized by the introduction of an extra complementary noncovalent interaction.
How to control interactions of cellulose-based biomaterials with skin: the role of acidity in the contact area
Authors: Gurtovenko Andrey A. , Karttunen Mikko
Published: June 2021

Adhesion of cellulose-based materials to the skin can be controlled via protonation of free fatty acids in the stratum corneum.
Task offloading and resource allocation algorithm based on mobile edge computing in Internet of Things environment
Authors: Liu Junwei
Published: June 2021

This paper proposes a task offloading and resource allocation algorithm based on mobile edge computing. Firstly, for the long‐term performance optimization of small base stations, the system model is established according to task arrival characteristics, credit relationship between small base stations, time delay and energy consumption of computing tasks and cable channel congestion. Secondly, the energy consumption deficit queue based on Lyapunov drift penalty technology used for the energy consumption constraint of small base stations in long‐term optimization process. The energy consumption deficit queue is established for each small base station to couple the energy consumption and time of small base stations, so that small base stations can meet the energy consumption constraints in long‐term optimization process. Finally, game theory is introduced to calculate offloading weight by the offloading weight model based on Shapley value. Besides, the offloading weight is calculated equitably according to the return of different tasks. Simulation results on MATLAB platform show that the proposed algorithm can achieve Nash equilibrium after finite iterations. Moreover, its performance on energy consumption, time delay and number of tasks successfully offloaded is better than other comparison strategies.
Columba livia time budget in the conditions of Kazan in spring
Authors: Basyyrov Aizat , Leonova Tamila
Published: June 2021

The daily time budgets of the rock pigeon (Columba livia) in the spring were studied basing on the example of birds with different foraging strategies. The connection between daylight hours and the birds’ night sleep was revealed. The relation between the daily routine and various forms of activity in birds with different foraging strategies was revealed.
Reproductive behavior of the european roller (Coracias garrulus Linnaeus, 1758)
Authors: Malovichko Liubov , Poddubnaya Nadezhda , Akimova Karina , Eltsova Liubov
Published: June 2021

In the European part of Russia, there is a decrease in the area and number of the European Roller. We performed a preliminary study of the role of behavioral ecology in the survival of the species. The material was collected in the Stavropol krai in 2004, 2006-2019. Females and males were distinguished by color intensity (females' plumage is paler) and behavior. Birds exhibit complex biocommunication with features of a foraging economy, distribution of parental roles, and high coordination of partner actions. Additional research is needed to elucidate the behavior of birds whose partners died in the flyover or wintering areas.
Anoplura (lice) infestation of the herb wood mouse Sylvaemus uralensis Pallas, 1811 in the Trans-Urals forest-steppe
Authors: Starikov V P , Kravchenko V N
Published: June 2021

The herb wood mouse is parasitized by Hoplopleura affinis Burmeister, 1839. For this research, the authors examined a total number of 408 herb wood mice for the presence of permanent ectoparasites (lice). The authors considered changes in the infestation rate in connection with the periods of the rodent’s life, the age and gender composition of the lice, the biotopic confinement peculiarities of the parasite in the conditions of the Trans-Urals forest steppe (Kurgan region). H. affinis is noted to be found on mammals in contact with the herb wood mouse.
Landscape and Climate Role in the Formation of Sturgeon Reproduction Biotopes in the Ural River (Zhaiyk)
Authors: Mikodina Ekaterina V. , Shalgimbaeva Gulmira M. , Volkov Alexander A.
Published: June 2021

Geoecology of the Ural River: landscape, climate, flora, and ichthyofaunal are given. Features of air and water temperature, winds, water sources, and balance are detailed. Information about Sturgeon fishes of the Acipenseridae family, the number of which is critical, is presented. The interaction of natural conditions and anthropogenic factors in the creature of spawning biotopes is described.
The impact of the COVID-19 pandemic on the environmental health of the Katunsky Biosphere Reserve
Authors: Rednikin Aleksey
Published: June 2021

This article shows the impact of the COVID-19 pandemic on the environment of the Katunsky reserve on the eco-trail “To the Land of Lakes and Waterfalls”. The research was carried out by three methods: assessment of trail degradation, camps and phytomass in damaged and reference areas. During the pandemic, a process of severe ecosystem degradation was identified, associated with a dramatic increase in the number of visitors to the reserve. Closed state borders and lifted restrictions on entry and exit to the Altai Republic have made the Katunsky Nature Reserve popular for recreational activities.
Potentially toxic elements distribution in the contaminated bottom sediments by the industrial genesis within Lower Don river system
Authors: Nevidomskaya Dina , Minkina Tatiana , Fedorov Yuri , Litvinov Yuri , Shcherbakov Alexei , Sherstnev Alexei , Mazarji Mahmoud
Published: June 2021

The work presents the results of studying the content of potentially toxic elements (Mn, Cu, Zn, Cr, Pb, Ni and Cd) in bottom sediments sampled at monitoring stations in the natural-anthropogenic systems of the Lower Don adjacent to the impact zone of the Novocherkassk Power Plant. The relationship between the content of metals in bottom sediments and their sorption properties is largely determined by the conditions of formation and the type of bottom sediments. Evaluation of the potentially toxic element content in sediments indicated that in particle size fractions (≤ 0.001 mm) could accumulate more than 15 times the levels of Cr and Zn and more than 6 times the levels of Cu, Cd and Ni in comparison to the particle size fractions that are 1.0 mm. Local zones of polyelemental pollution of bottom sediments with respect to Cu, Zn, Pb Cd and Cr were determined. These zones are confined to the geochemical sorption barriers of small watercourses of the power plant.
Accumulation of heavy metals in the organs of herbaceous plants
Authors: Reut Antonina , Biglova Aigul , Allayarova Irina
Published: June 2021

The purpose of the work is to establish the characteristics of the accumulation of heavy metals of aboveground and underground organs in plant samples of 8 varieties of Narcissus hybridus and Camassia cusickii in the urbanized environment of the city of Ufa. The study of the elemental composition of the samples was carried out according to the method of quantitative chemical analysis ‘Determination of As, Pb, Cd, Sn, Cr, Cu, Fe, Mn and Ni in laboratory samples of food products and food raw materials by the atomic absorption method with electrothermal atomization’. It was found that the content of nickel, copper, cadmium, lead, magnesium, iron, chromium in all the samples studied does not exceed the standards specified in the State Pharmacopoeia of the Russian Federation (SP RF). The arsenic content exceeds the standards specified in the SP RF by 3.4 times. Revealed a high intensity of biological absorption of copper. It has been established that the concentrations of As, Cu, Pl, Mn, Fe in the aboveground organs are higher than in the underground part of plants; the ratio of the content of Ni, Cr, Cd in aboveground and underground organs is the same.
Content of heavy metals and arsenic in soils near Sharra landfill (Tirana, Albania)
Authors: Chernykh Natalia , Baeva Yulia , Thoma Anamaria
Published: June 2021

The paper presents the results of a comparative assessment of the degree of pollution of subtropical brown soils with a number of heavy metals (V, Mo, Co) and arsenic in the zone of influence of solid municipal waste landfill “Sharra”. The landfill is located about 7 km southwest of the center of Tirana. Until the early 1990s it was used mainly for the disposal of industrial waste, subsequently it became an uncontrolled open dump and is now the dumping area for all waste of the capital city of the Republic of Albania. Total metal and As contents were determined by inductively coupled plasma atomic emission spectrometry in samples from 14 sites at different distances from the landfill body. Concentrations of V - in 1.2-1.3 times, Mo - more than in 2.2-4.4 times, Co - in 1.2-1.5 times and As - more than in 3.4 times were exceeded background concentration. It was also revealed 1.7 times higher than the established normative value for As in soils. The obtained results confirm the hypothesis about the negative impact of the Sharra landfill on the adjacent territories.
Establishment of regional background for heavy metals in the soils of the Lower Don and the Taganrog Bay coast
Authors: Konstantinova Elizaveta , Minkina Tatiana , Nevidomskaya Dina , Bauer Tatiana , Fedorov Yuri , Zamulina Inna , Mandzhieva Saglara , Kravtsova Natalia , Voloshina Marina , Dudnikova Tamara , Shcherbakov Aleksey
Published: June 2021

Data on the regional geochemical background and threshold values of heavy metals are required to establish anomalies and assess soil pollution. As a rule, the background values are the average contents of elements in natural undisturbed soils, or the threshold values for the study area, obtained by statistical methods. The aim of the study is to obtain geochemical threshold values of heavy metals in the soils of the Lower Don and the Taganrog Bay coast using different statistical approaches. A total of 86 topsoil samples were collected from the study area. The concentrations of Cr, Mn, Ni, Сu, Zn, As, Cd, and Pb were analyzed by X-ray fluorescence. The median element concentrations in the soils of the study area were consistent with world soil average and metal concentrations in background soils of protected area. Using a ‘geochemical’ approach is not suitable for this dataset because it does not take into account the natural variability of concentrations in different soil types. The Tukey inner fence method delivers estimates that do not detect outliers for Ni, As, Cd, and Pb. The ‘median + 2 median absolute deviations’ method was the most appropriate, as it consistently provided the most conservative background values.
Assessment of agricultural land loss due to mining in Moscow region
Authors: Naumova Ksenia , Stanis Elena , Latushkina Elena , Buldovich Nikolai
Published: June 2021

The study discusses the impact of open cuts for the extraction of common minerals on soil resources and agricultural lands in Moscow region (MR). For this, the features of soil cover in Moscow region and the distribution of soil types by their use as agricultural resources were analyzed. Further, it was determined which types of soils are subject to varying degrees of open cut load. As a result, a schematic map of the soil cover with open cut load zones was made. It is shown which agricultural lands exposed to open cuts of varying intensity. A conclusion is made about the types of soil cover, which accounts for the greatest and least open cut load, as well as the degree of impact of open cuts on agricultural land resources and the correlation between the degree of open cut load and type of agricultural land use. It is shown that the most fertile soils, which occupy only 2.9% of the MR area, are not affected by the open cut load at all. The greatest open cut load is associated with agricultural lands, represented mainly by various sod-podzolic soils, which occupy 70.5% of the territory of the Moscow region. If economic trends and population growth rates in the Moscow region continue until 2030, we should expect a further increase in the influence of open cut load on agricultural land towards its intensification.
The necessity of ascertaining contamination by dust using soil spectral reflectance as its indicator
Authors: Ankomah Baah Gabriel , Savin Igor
Published: June 2021

Pollution of the urban environment by human disturbances and activities is a negative externality of urbanization, therefore becoming a great concern due to the serious problems associated with human health. The mobilization of heavy metals into the biosphere by human activities has become an important process in the geochemical recycling of these metals. Though the risks of exposure to road dust have been reported to be higher for individuals than those in soil, little attention has been paid to the occurrence characteristics of heavy metals in dust and its associated health risks to the population. In the present studies, the physical, chemical and spectral signatures gained from dust and soil constituents would be differentiated based on their reflectance in specific bands of the electromagnetic spectrum. It is expected that the analysis of road dust and soil samples will indicate spectral signatures exhibiting differences in specific wavelengths of the spectrum, hence, indicating their spectral discrimination, as well as the presence of heavy metals showing its reflectance based on its concentration. The expected outcome of this study can be used to provide a theoretical basis for controlling the risk of heavy metals exposure to population.
Industrial method of decontamination of dimethoate containing wastewater
Authors: Vasylenko Volodymyr , Sidorenko Marina , Mickevičius Saulius
Published: June 2021

The problem of wastewater disposal affects not only third countries, but also world giants such as China or the United States of America. The European Union and the Commonwealth of Independent States are no exception. The increasing use of organophosphate pesticides requires the search for new, more efficient and cheaper ways to dispose of their residual amounts. The existing methods of disposal of toxic waste are costly, ineffective, and environmentally hazardous. The optimal solution can be a chemical system for decontamination of wastewater directly at the place of their origin, for example, at the production of pesticide formulations and agro-industrial facilities. This article presents the results of studying the effectiveness of the chemical system for the destruction of organophosphorus compounds based on hydrogen peroxide and potassium hydroxide in relation to dimethoate. The results of the scaling of the decontamination process are presented and an installation for the technological process of wastewater disposal is proposed. The research results show a high reactivity of the system under study and a high efficiency level of the described technological process.
The compost metagenome as a source of T4 bacteriophage pyrimidine dimer glycosylase homologues
Authors: Karmanova Alexandra N. , Lu Yinhua , Zimin Andrei A.
Published: June 2021

Compost is a promising source of thermotolerant enzymes for their application in biotechnology. Homologues of bacteriophage T4 DNA glycosylase can find their application in pharmaceuticals and perfumery. Five homologues of glycosylase of pyrimidine dimers of bacteriophage T4, a product of the denV gene, were found by comparing using the DELTA-BLAST algorithm with the compost metagenome proteins. Phylogenetic analysis of the found sequences of enzyme homologues was carried out using the Maximum Likelihood algorithm in the MegaX software package. Thus, an interesting spectrum of promising proteins, homologues of the repair enzyme, DNA glycosylase of pyrimidine dimers of bacteriophage T4, was found. After structural modeling, they can be tested for their thermal stability and tested as a basis for therapeutic and prophylactic drugs.
Prospects for green hydrogen production in the regions of Russia
Authors: Nefedova Liudmila , Degtyarev Kirill , Kiseleva Sophia , Berezkin Mikhail
Published: June 2021

The article discusses the possibilities of hydrogen production using renewable energy sources in Russia for energy storage and for export. The global trends in the development of green hydrogen energy reducing the CO2 emission are highlighted. The analysis of the potential for hydrogen production in regions of Russia using electricity from operating wind power plants (WPPs), as well as wind power projects planned for construction until 2024 has been carried out.
Biotechnology based on cell cultures of higher plants
Authors: Nourani Amira , Popova Elena , Titova Maria
Published: June 2021

This paper reviews the role of plant cell culture as a biotechnological tool in preserving the botanical diversity of higher plants while meeting the growing demand of the commercial market for large volumes of plant raw material. The prospects of plant cell-based technology are discussed in the framework of creating an economy of sustainable development in the short and long term.
Integrative principles and criteria for implementation of faecal sludge management in Russian Federation
Authors: Basamykina Alena , Kurkina Ekaterina , Kameristaya Maria , Zelenina Valeria
Published: June 2021

Faecal sludge management (FSM) is an organized program that allows regularly to collect, transport, process and utilize faecal sludge as biological waste. A faecal sludge management in settlements in Russian Federation is so bad organized or only partially exist. There are significant gaps as well as general understanding of institutional roles and responsibilities at national, state and city levels. Planning should be done in a temporal and spatial context. Сities, while maintaining short-term stability, will be guided by the goals of a long-term vision of creation. Planning system of faecal sludge management in Russian Federation that involves these blocks: regulatory framework, selection of best available techniques (BAT), financing and planning mechanisms, is analyzed. Integrated approach to the creation and regulation of a faecal waste management are shown. For implementation such approach, a system of evaluation criteria is required in order to determine the end product and, accordingly, determine development direction of this industry in the geographical area where this system will operate.
To the conservation of biodiversity of North Ossetia: an environmental and political aspect
Authors: Koibaev B.G. , Lamarton S.F.
Published: June 2021

This work shows that one of the main indicators of the ecological component of the modern process leading to the destruction of the biodiversity of the main faunistic complexes is a barbaric attitude towards limited natural resources. The main attention is paid to the legal mechanism for controlling the purposeful extermination of the animal world, pollution of the water basin, which will stabilize the state of ecosystems that are extremely important for the life support of the population (water and terrestrial biological resources). It is concluded that the current situation requires the creation of regulatory state mechanisms to ensure the environmental and national security of the republic and the entire Central Caucasus, as a unique natural region. The ecological function of the state as a guarantor of ecological safety and as a part of the national security system has been substantiated.
Rainwater harvesting potentials for drought mitigation in Tunisia: Water quality monitoring
Authors: Mansouri Fatma , Gasmi Ines , Moussa Mohamed , Ksibi Mohamed
Published: June 2021

Rainwater is extremely important for the arid regions of Tunisia for a better valorization of this water, the indigenous of these regions decided to build earthen cisterns (Majel and Fesquia) to collect rain water, to satisfy their needs and to have sufficient long-term water reserve in case of prolonged drought. Despite the difficulties faced to access the mountainous regions, a survey was conducted concerning all characteristics of earthen cisterns and their uses. 120 samples of water have been analyzed in the laboratory for their physicochemical parameters such as pH, EC, sodium, chloride, bicarbonate and microbiological quality parameters such as total coliforms, and Escherichia coli. It has been noted that the majority of people (62%) used rainwater as drinking water, for animal watering and as supplementary irrigation. In fact, physic-and chemical properties of, the rainwater samples collected are suitable for consumption according to WHO 2017 standards. However, the results of our microbiological indicator analyses suggested that rainwater stored in Majel and Fesquia are not suitable for human consumption without any treatment. Rainwater can be considered as potential source for non-potable uses, such as irrigation. The samples collected were categorized as suitable with regard of SAR belonged to the excellent to good class.
Geographical origin identification of teas using UV-VIS spectroscopy
Authors: Tran Thi Hue , Tran Quoc Toan , Ta Thi Thao , Le Si Hung
Published: June 2021

In this work we proposed a method to verify the differentiating characteristics of simple tea infusions prepared in boiling water alone, which represents the final product as ingested by the consumers. For this purpose, total of 125 tea samples from different geographical provines of Vietnam have been analyzed in UV-Vis spectroscopy associated with multivariate statistical methods. Principal Component Analysis-Discriminant Analysis (PCA-DA), Partial Least Squares Discriminant Analysis (PLS-DA) and Artificial Neural Network (ANN) were compared to construct the identification model. The experimental results showed that the performance of ANN model was better than PCA-DA and PLS-DA model. The optimal ANN model was achieved when neuron numbers were 200, identification rate being 99% in the training set and 84% predition set. The proposed methodology provides a simpler, faster and more affordable classification of simple tea infusions, and can be used as an alternative approach to traditional tea quality evaluation.
Using the project method to improve environmental education for law students
Authors: Yekimov Sergey , Karmanny Yevhenii , Zenin Andrii , Zinovatna Iliana , Sliusarenko Serhii
Published: June 2021

Training a modern professional who can use a creative approach within the framework of their professional activities , as well as to easily adapt to many modern technological changes, requires the use of modern innovative pedagogical technologies in the training process. When performing this study, we used the project method to increase environmental awareness and environmental thinking among students of the specialty law. Environmental education is learning through the environment, for the environment, and about the environment. The authors believe that it should be universal, and its components should be present in preschool, school, vocational, higher, and postgraduate professional education. We believe that the greatest effect can be achieved by continuing environmental education, provided that it becomes an indispensable attribute of personal development. The results of the implemented project showed that the students of law have increased their
Patriotic self-identification: the case study of Ecological Faculty students at RUDN University
Authors: Zakirova Yulia , Lazareva Anastasia , Nwankwo Nnabueze Kalu
Published: June 2021

The paper aims at providing the initial report of the mental reactions of Ecological Faculty students of RUDN University to the concept of patriotism. The term “patriotism” is used to refer to love of a country as well as to an ideology, which holds that one’s primary allegiance should be to one’s country and its citizens’ needs. Patriotism is considered as a virtue and environmentalism – as one of its important manifestations. The subjects for the present study were 66 Bachelor’s students of Ecological Faculty of RUDN University. The survey was conducted in September-October 2020. The participants completed a self-administered questionnaire. The results were assessed and the conclusions related to the current stage of the study were made.
On the issue of a favorable environment in the “Smart City” development program
Authors: Vakula Marina A.
Published: June 2021

The article examines acute problems of ensuring a favorable environment in urbanized areas. The author pays special attention to the greening of the urban economy by implementing the “Smart City” program’s digital technologies. The study rests on research and particular scientific methods of cognition. The dialectical method made it possible to ensure a favorable environment in urban areas and, in conjunction with indicators, assess its quality. The comparative legal method is taken as a basis for identifying general trends in the use of new information technologies to determine the quality of a favorable environment. The article emphases that the implementation of information technology in ensuring a favorable environment contributes to an increase in the effectiveness of measures aimed at protecting it from negative influences. Simultaneously, indications of the effectiveness of the implementation of promising programs, including the Smart City program, use virtual indicators that are not accompanied by indicators that allow assessing the degree of environmental friendliness in quantitative terms. The article contains suggestions for improving the mechanism for protecting a favorable environment in the “Smart City” development program.
“Flow Reversal” and Cure in a Case of Giant Intracranial Aneurysm: A Case Report
Authors: Shah Abhidha , Vutha Ravikiran , Doshi Jash , Trivedi Nishit , Goel Atul
Published: June 2021

We describe the case of an 11-year-old girl having a giant anterior circulation aneurysm. The ipsilateral internal carotid artery was entirely blocked and the aneurysm was supplied by posterior circulation. Following a high-flow bypass that connected the external carotid artery to the middle cerebral artery, the giant aneurysm thrombosed spontaneously. We discuss several relatively rare and unique features of the case.
Wound Care for Venous Ulceration
Authors: Schroeppel DeBacker Sarah E. , Bulman Julie C. , Weinstein Jeffrey L.
Published: June 2021

Venous leg ulcers (VLUs) affect as many as 20% of patients with advanced chronic venous insufficiency and are associated with significant morbidity and health care costs. VLUs are the most common cause of leg ulcers; however, other etiologies of lower extremity ulcerations should be investigated, most notably arterial insufficiency, to ensure appropriate therapy. Careful clinical examination, standardized documentation, and ultrasound evaluation are needed for diagnosis and treatment success. Reduction of edema and venous hypertension through compression therapy, local wound care, and treatment of venous reflux or obstruction is the foundation of therapy. As key providers in venous disease, interventional radiologists should be aware of current standardized disease classification and scoring systems as well as treatment and wound care guidelines for venous ulcers.
Thirty-Day Unplanned Readmission after Total Hip Arthroplasty at a Community Hospital: Rates, Reasons, and Risk Factors
Authors: Workman Kalain , Folau Christopher K. , Phillips David S.
Published: June 2021

Unplanned readmission after total hip arthroplasty (THA) has an increasing prevalence in the United States. Readmissions are a metric for a hospital's quality of care, yet the reasons behind them are mixed. In this changing health-care environment, it is critical for institutions to identify the risk factors for unplanned readmissions following a THA. Retrospective chart review and hospital administrative database query were used to report causes, demographics, and medical comorbidities linked to a 30-day readmission after primary THA at a teaching community hospital system. This study identified 4,459 primary THA procedures, of which 96 (2.2%) were unplanned readmissions. Periprosthetic fracture (20.8%) and periprosthetic infection (17.7%) were the most common causes of readmission. Patients discharged to rehab (odds ratio [OR], 2.44; 95% confidence interval [CI], 1.36–4.37; p = 0.0026) were correlated significantly with the risk of 30-day readmission. Anemia (OR, 2.62; 95% CI, 1.44–4.79; p = 0.0016), obstructive sleep apnea (OR, 2.27; 95% CI, 1.17–4.4; p = 0.0150), and asthma (OR, 2.51; 95% CI, 1.17–5.40; p = 0.0184) were significant independent risk factors. Charlson comorbidity index (p = 0.3634) was not shown to correlate with a quicker readmission within 30 days of discharge. Patients with a history of anemia, obstructive sleep apnea, and asthma should be medically optimized before and after undergoing THA in the community setting. Implementing postsurgical emphasis on discharging patients with home care options rather than transferring them to a rehabilitation facility may prevent 30-day readmissions.
Effect of a Dichotic Interaural Time Difference Program on Dichotic Listening Deficit of Children with Learning Difficulty
Authors: Mahdavi Mohammad Ebrahim , Rezaeian Maryam , Zarrinkoob Homa , Rezaeian Mohsen , Akbarzadeh Alireza
Published: June 2021

Abstract Background Dichotic listening deficit (DLD) is a common sign in children showing learning problem and is identified during auditory processing assessment. A dichotic listening training program was developed in which the weak ear lags behind the strong
ear in time and has certain practices for switching attention between the ears and auditory memory. Purpose The aim of the present study was to evaluate the effectiveness of this treatment program on dichotic performance of primary school children showing DLD. Research
Design A pre/post clinical trial without control study. Study Sample Twenty-five primary school children, aged 7 to 12 years (mean = 9.3 years), showing DLD. Data Collection and Analysis Several primary schools referred the children with
learning difficulty to us. We defined learning difficulty as a score of 2 and lower on a five-point scale in at least two primary school courses in the current semester. The children with DLD participated in listening practices three times a week for 10 weeks, each session lasting for 30 minutes.
The practices started with one pair of dichotic digits and ended in practice with sentences. The weak ear lag varied from 100 to 1,000 milliseconds. In the last stage of the practices, the precued and postcued directed response aimed at strengthening auditory memory and switching attention
between the ears. The results obtained by the tests of dichotic digits, competing words, and competing sentences before and after the intervention were compared using paired t-test. Hedges's g was calculated as the effect size. Results Comparison of the results of pretraining
and those of posttraining revealed that the average dominant ear (DE) and nondominant ear (NDE) scores in dichotic listening tests improved significantly with medium-to-large effect sizes. It was also found that the mean change in the NDE score of the children was significantly greater than
that of the DE score for all the tests. Conclusions Dichotic interaural time difference training that employed dichotic lag phenomenon followed by directed response practices significantly improved the DE and the NDE scores of the schoolchildren with DLD.
Investigating the Effect of Hearing Aid Use on the Balance Status of Children with Severe to Profound Congenital Hearing Loss Using the Pediatric Clinical Test of Sensory Interaction for Balance
Authors: Hamzehpour Farzad , Absalan Aghil , Pirasteh Ebrahim , Sharafi Zahra , Arbabsarjoo Hamideh
Published: June 2021

Abstract Background Since the hearing and vestibular organs are close to each other, the correlation between hearing and balance is one of the principal issues, especially in people with hearing loss. Purpose In this study, the effect of the auditory
system on human balance performance was investigated by comparing the balance status of hearing-impaired children in the aided and unaided situations. Research Design In this cross-sectional study a group of children were assigned the task to compare the balance sways in two
aided and unaided situations. Study Sampling A total of 90 children aged 7 to 10 years with severe to profound congenital hearing loss and the healthy vestibular system of both genders served as the research population. Data Collection and Analysis After a complete
evaluation of the hearing and vestibular system and validation of the hearing aid performance, body sway was recorded using the pediatric clinical test of sensory interaction for balance in aided and unaided situations in the presence of background noise from the speaker. Results According
to this study, there was no difference in body sway in aided and unaided situations for conditions 1, 2, and 3. In comparison, in conditions 4, 5, and 6 of the test, there was a statistically significant difference in body sway between aided and unaided situations. However, there was no difference
in the sway of the body in aided and unaided situations between girls and boys. Conclusion According to this study, hearing aids can improve balance in challenging listening environments.
Management of Patients when Superficial Venous Disease Arises from Pelvic Escape Points
Authors: Ahuja Rakesh S. , Garg Tushar , Sudheendra Deepak
Published: June 2021

Chronic pelvic pain (CPP) is a common condition in women that carries with it significant morbidity. It is commonly seen in patients presenting to obstetrics and gynecology outpatient clinic visits. CPP is a presenting symptom of various pathologies including pelvic varicocele, pelvic adhesions, spastic colon syndrome, uterine fibroids, endometriosis, and psychosomatic disorders. Pelvic congestion syndrome has more recently been termed “pelvic venous insufficiency (PVI)” due to the underlying retrograde flow through incompetent ovarian and pelvic veins that are thought to cause the symptoms of CPP. Pelvic varices can commonly present alongside vulvar, perineal, and lower extremity varices. There are some predictable “escape pathways” for these varices that may present for interventional treatment. This article introduces the reader to current terminology, clinical presentation, diagnosis, and treatment of patients with pelvic varices due to PVI.
Clinical Presentation, Patient Assessment, Anatomy, Pathophysiology, and Imaging of Pelvic Venous Disease
Authors: Maratto Sean , Khilnani Neil M. , Winokur Ronald S.
Published: June 2021

Pelvic venous disorders (PeVDs) can result in several different clinical presentations, but can be challenging to distinguish from other etiologies of chronic pelvic pain (CPP). Clinical evaluation of CPP patients optimally should be performed in a multidisciplinary fashion and patients who may have PeVD should be referred for consultation with a vascular interventionalist whose evaluation would utilize an imaging workup to search for pelvic varices. Additionally, it is critical to quantify the quality-of-life effects of all CPP to determine the impact on the patient's overall health. Diagnostic imaging, including transabdominal and transvaginal ultrasound, computed tomography, magnetic resonance imaging, and venography, can be utilized to identify pelvic varices, as well as venous reflux and obstruction leading to CPP. The use of the SVP tool is important to classify PeVD patients based on their clinical symptoms, varicose veins, and pathophysiology for precise clinical communication and for reporting clinical research. The goal of this publication is to delineate the clinical presentation, anatomy, pathophysiology, and imaging evaluation of patients with CPP suspected of having PeVD.
Developing the Minimum Dataset for the New Mexico Decedent Image Database
Authors: Daneshvari Berry Shamsi , Kroth Philip J. , Edgar Heather J. H. , Warner Teddy D.
Published: June 2021

Background A minimum dataset (MDS) can be determined ad hoc by an investigator or small team; by a metadata expert; or by using a consensus method to take advantage of the global knowledge and expertise of a large group of experts. The first method is the most commonly applied.

Objective Here, we describe a use of the third approach using a modified Delphi method to determine the optimal MDS for a dataset of full body computed tomography scans. The scans are of decedents whose deaths were investigated at the New Mexico Office of the Medical Investigator and constitute the New Mexico Decedent Image Database (NMDID).

Methods The authors initiated the consensus process by suggesting 50 original variables to elicit expert reactions. Experts were recruited from a variety of scientific disciplines and from around the world. Three rounds of variable selection showed high rates of consensus.

Results In total, 59 variables were selected, only 52% of which the original resource authors selected. Using a snowball method, a second set of experts was recruited to validate the variables chosen in the design phase. During the validation phase, no variables were selected for deletion.

Conclusion NMDID is likely to remain more “future proof” than if a single metadata expert or only the original team of investigators designed the metadata.
Instrument for spatially resolved, temperature-dependent electrochemical impedance spectroscopy of thin films under locally controlled atmosphere
Authors: Papac Meagan C. , Talley Kevin R. , O’Hayre Ryan , Zakutayev Andriy
Published: June 2021

We demonstrate an instrument for spatially resolved measurements (mapping) of electrochemical impedance under various temperatures and gas environments. Automated measurements are controlled by a custom LabVIEW program, which manages probe motion, sample motion, temperature ramps, and potentiostat functions. Sample and probe positioning is provided by stepper motors. Dry or hydrated atmospheres (air or nitrogen) are available. The configurable heater reaches temperatures up to 500 °C, although the temperature at the sample surface is moderated by the gas flow rate. The local gas environment is controlled by directing flow toward the sample via a glass enclosure that surrounds the gold wire probe. Software and hardware selection and design are discussed. Reproducibility and accuracy are quantified on a Ba(Zr,Y)O3−δ proton-conducting electrolyte thin film synthesized by pulsed laser deposition. The mapping feature of the instrument is demonstrated on a compositionally graded array of electrocatalytically active Ba(Co,Fe,Zr,Y)O3−δ thin film microelectrodes. The resulting data indicate that this method proficiently maps property trends in these materials, thus demonstrating the reliability and usefulness of this method for investigating electrochemically active thin films.