bluuebunny/crossref_metadata_2025 huggingface dataset:
Aqueous Flare, Functional-Morphological Parameters, and Cytokines in Age-Related Macular Degeneration after Anti-VEGF Treatment
Authors: Motohashi Ryosuke , Noma Hidetaka , Yasuda Kanako , Kasezawa Yuko , Goto Hiroshi , Shimura Masahiko
Published: November 2021

Purpose:

The role of inflammation and cytokines in AMD and anti-Vascular Endothelial Growth Factor (anti-VEGF) treatment remains unclear. Therefore, this study aimed to examine whether anti-VEGF treatment for exudative Age-related Macular Degeneration (AMD) affects aqueous flare value (an indicator of inflammation), functional-morphologic parameters, and aqueous humor levels of cytokines or inflammatory mediators.

Methods:

We compared aqueous humor levels of 8 cytokines, growth factors (including VEGF), and inflammatory mediators in 43 patients who received anti-VEGF treatment with aflibercept for AMD and 24 healthy controls by the suspension array method. In addition, we measured aqueous flare values with a laser flare meter and Central Macular Thickness (CMT) and Macular Volume (MV) by optical coherence tomography.

Results:

The patient group had a significantly higher aqueous flare value than the control group. At baseline, CMT showed significant correlations with aqueous humor levels of soluble intercellular adhesion molecule-1 (sICAM-1), monocyte chemoattractant protein 1 (MCP-1), interleukin (IL)-6, and IL-8 and MV, with aqueous humor levels of VEGF, sICAM-1, MCP-1, IL-6, and IL-8. Moreover, we found significant correlations between aqueous flare value and aqueous humor levels of MCP-1, IL-6, IL-8, and interferon-gamma–inducible protein 10. One month after anti-VEGF treatment, the patient group showed a significant correlation between the change in MV and improvement in best-corrected visual acuity (BCVA); CMT showed no such correlation.

Conclusion:

Inflammation appears to be involved in AMD. Change in MV may be an index of improvement in BCVA in patients receiving anti-VEGF treatment for AMD.
Validation of a Predictive Model of Pre-eclampsia from a Cohort Study in Pregnant Women
Authors: Vadell Haydée C. , Barroso Reinaldo L. , Dieguez Aglae C. , Pujals Adrian M. , Á. Guerra Eloy D.
Published: November 2021

Background & Aims:

To validate a predictive model of pre-eclampsia for classifying pregnant women into pre-eclamptic and healthy groups.

Materials and Methods:

A cohort study was carried out in a total of 132 pregnant women, including biochemical and clinical parameters for assessing the classification performed by a predictive model of pre-eclampsia from a 10-fold cross-validation method and the experts’ criteria.

Results:

A highly predictive value was obtained from the set of biochemical parameters included in the proposed model. Wilks’ Lambda, eigenvalues, canonical correlation, and distances between centroids of the groups point to the high classificatory power of the discriminant function. Risk indexes, computed from the centroids, provided a measure of different risk levels for this condition. The analysis of these indexes in a prospective study allowed assessing the effect of the parameters. The new ten models obtained from a 10-fold cross-validation achieved a 100% of correct classification (AUC:1.00; CI:0.00-1.00; p=0.00). The sensitivity and specificity of the model, obtained from ROC curves, showed the consistency of the model, even though there were only four clinical manifestations of the entity. Moreover, the risk indexes were assessed from the experts’ criteria in the cohort study, showing an AUC of 100% in the 3rd trimester of pregnancy.

Conclusions:

The model and proposed pre-eclampsia risk indexes could constitute an accurate diagnostic tool, employing markers of oxidative stress as a significant element in the prediction of this entity.
International anti-corruption standards
Authors: Topchii Vasyl , Zadereiko Svitlana , Didkivska Galyna , Bodunova Olesia , Shevchenko Dmytro
Published: November 2021

The article studies the issues of combating corruption in the aspect of its incorporation into international standards. Corruption has been identified as a threat to democracy and economic development in many States. It arises from the process of the exchange of power for material assets, that is, when a competent person performs or refrains from performing certain actions for remuneration, and due to the weakness or weakness of the state, political, and public institutions that control and limit these processes. It is noted that the world community is seriously thinking about those negative consequences (threat of statehood, undermining trust in the authorities, causing harm to the individual, society, the functioning of organized crime, a drop in the level of professionalism of employees, a decrease in the level of legal awareness of spirituality) caused by corruption, and realizes that all States need to act as one to achieve serious positive results. It is noted that the international community, to develop effective measures to prevent and eradicate corruption, has adopted several international treaties, as well as recommendations that are not binding but are used by States as effective mechanisms for monitoring corruption.
International tourism as a tool of European integration within eastern European countries
Authors: Parfinenko Anatoliy , Yevtushenko Olena , Panova Iryna , Podlepina Polina , Onatskyi Maksym
Published: November 2021

The article is devoted to researching the links between European integration processes and the development of national markets for tourist services. Particular attention was paid to the situation in international tourism in those countries that integrated with the EU in 2004 and 2007. In addition, the article discusses the main modern types of international tourism, as well as factors affecting its development. Finally, attention was also paid to identifying promising directions for the development of international tourism in Eastern European countries – potential candidates for accession to the EU (Republic of Moldova and Ukraine).
Mindfulness-Based Stress Reduction as a Whole-System Approach to Health Care Delivery: Brief Report from a Pilot Training Program Developed for Clinicians
Authors:   Department of Psychology, University of Nevada, Reno, USA, Hazlett-Stevens Holly
Published: November 2021

Mindfulness-Based Stress Reduction (MBSR) is an evidence-based health education program for medical patients with a variety of chronic conditions. MBSR also benefits health care providers themselves, decreasing work-related stress and preventing burnout. The objectives of this study were to describe an abbreviated MBSR curriculum developed for health care providers and to present initial program evaluation data assessing acceptability and outcomes. This program was implemented outside the research context with an open trial design. Mindfulness training sessions were held in a conference room at the administrative offices of a large, non-profit community health care system. Five clinic providers, three male and two female, included four primary care physicians and one social worker. All five participants participated in and completed the training. A six-session abbreviated MBSR protocol was developed. Participants attended weekly two-hour group sessions scheduled at the end of the workday. Standardized self-report questionnaires included the Perceived Stress Scale (10-item version) and the Copenhagen Burnout Inventory. Participants also completed four rating items designed to assess their personal satisfaction with the program. All five clinicians reported satisfaction with the program and measurable reductions in perceived stress and personal burnout. Statistically significant reductions in perceived stress and personal burnout scores across the group also were found. Abbreviated MBSR programs for clinicians may support clinician welfare by reducing stress and preventing burnout, ultimately impacting the larger health care delivery system in health-promoting ways. Research examining the effectiveness of specific protocols for clinicians is needed to support further dissemination and implementation.
Pengaruh Brand Equity Terhadap Minat Pemanfaatan Kembali Pelayanan Pada Instalasi Rawat Inap Rumah Sakit Ibnu Sina Makassar
Authors: . Sumarni
Published: November 2021

Ekuitas merek adalah keinginan dari seseorang untuk melanjutkan menggunakan suatu brand atau tidak. Penelitian ini bertujuan menganalisis pengaruh Ekuitas Merek terhadap minat pemanfaatan kembali pelayanan pada Instalasi Rawat Inap Rumah Sakit Ibnu Sina Makassar. Penelitian ini menggunakan pendekatan kuantitatif dengan rancangan cross sectional study. Populasi penelitian sebanyak 4390 orang dan sampel sebanyak 151 orang. Pengumpulan data dilakukan chi square dan uji regresi logistic pada p=0,05. Hasil penelitian menunjukan bahwa tidak ada pengaruh variabel kesadaran merek terhadap minat pemanfaatan kembali pelayanan pada Instalasi Rawat Inap Rumah Sakit Ibnu Sina (p=0,319). Ada pengaruh positif variabel asosiasi merek terhadap minat pemanfaatan kembali pelayanan pada Instalasi Rawat Inap Rumah Sakit Ibnu Sina (p=0,022).Ada pengaruh positif variabel persepsi kualitas terhadap minat pemanfaatan kembali pelayanan pada Instalasi Rawat Inap Rumah Sakit Ibnu Sina (p=0,002). Ada pengaruh positif variabel kesetian merek terhadap minat pemanfaatan kembali pelayanan pada Instalasi Rawat Inap Rumah Sakit Ibnu Sina (p=0,022). Ada pengaruh positif variabel aset merek lain terhadap minat pemenfaatan kembali pelayanan pada Instalasi Rawat Inap Rumah Sakit Ibnu Sina (p=0,001). Variabel kesetian merek merupakan faktor yang paling berpengaruh positif terhadap minat pemanfaatan kembali pelayanan pada Instalasi Rawat Inap Rumah Sakit Ibnu Sina ρ=0,993 dan wald = 5,997. Secara keseluruhan semua model variable dapat mempengaruhi minat pemanfaatan kembali Instalasi Rawat Inap Rumah Sakit Ibnu Sina sebesar 93,4%.

Kata kunci: Ekuitas merek, Minat pemanfaatan kembali
Contemporary English Pain Descriptors as Detected on Social Media Using Artificial Intelligence and Emotion Analytics Algorithms: Cross-sectional Study (Preprint)
Authors: Tan Ming Yi , Goh Charlene Enhui , Tan Hee Hon
Published: November 2021

BACKGROUND

Pain description is fundamental to health care. The McGill Pain Questionnaire (MPQ) has been validated as a tool for the multidimensional measurement of pain; however, its use relies heavily on language proficiency. Although the MPQ has remained unchanged since its inception, the English language has evolved significantly since then. The advent of the internet and social media has allowed for the generation of a staggering amount of publicly available data, allowing linguistic analysis at a scale never seen before.

OBJECTIVE

The aim of this study is to use social media data to examine the relevance of pain descriptors from the existing MPQ, identify novel contemporary English descriptors for pain among users of social media, and suggest a modification for a new MPQ for future validation and testing.

METHODS

All posts from social media platforms from January 1, 2019, to December 31, 2019, were extracted. Artificial intelligence and emotion analytics algorithms (Crystalace and CrystalFeel) were used to measure the emotional properties of the text, including sarcasm, anger, fear, sadness, joy, and valence. Word2Vec was used to identify new pain descriptors associated with the original descriptors from the MPQ. Analysis of count and pain intensity formed the basis for proposing new pain descriptors and determining the order of pain descriptors within each subclass.

RESULTS

A total of 118 new associated words were found via Word2Vec. Of these 118 words, 49 (41.5%) words had a count of at least 110, which corresponded to the count of the bottom 10% (8/78) of the original MPQ pain descriptors. The count and intensity of pain descriptors were used to formulate the inclusion criteria for a new pain questionnaire. For the suggested new pain questionnaire, 11 existing pain descriptors were removed, 13 new descriptors were added to existing subclasses, and a new Psychological subclass comprising 9 descriptors was added.

CONCLUSIONS

This study presents a novel methodology using social media data to identify new pain descriptors and can be repeated at regular intervals to ensure the relevance of pain questionnaires. The original MPQ contains several potentially outdated pain descriptors and is inadequate for reporting the psychological aspects of pain. Further research is needed to examine the reliability and validity of the revised MPQ.
Usability of mobile applications: A Concept Analysis to be used in health promotion (Preprint)
Authors: Kung Po-Jen , Chen Ching-Min
Published: November 2021

BACKGROUND

Following the rise of health awareness in modern societies, health promotion has attracted progressively more attention in both academia and industry. This, along with the evolution of information and communication technologies, has resulted in the development of several mobile applications used in health promotion. Unfortunately, users of the applications have not achieved their goals, since many applications have not provided a smooth user experience.

OBJECTIVE

To clearly identify the defining attributes of mobile app usability in the context of health promotion in order to guide the design of apps which provide smooth user experience.

METHODS

It is thus first necessary to conduct an exploration into app usability, for which this study applies the concept analysis method by Walker and Avant, which includes: (1) identifying the use of the concept, (2) determining the defining attributes, (3) constructing a model case, (4) constructing model, contrary, borderline, and related cases, (5) identifying antecedents and consequences, and (6) defining empirical referents.

RESULTS

We then derive a unified definition of usability from the healthcare perspective—that the defining attributes of "usability of mobile application" are: efficiency, user satisfaction, and learnability.

CONCLUSIONS

It is concluded that mobile applications with these attributes could achieve their designed goals and reach maximal efficacy, since users would continue using the app on a regular basis, and would recommend it to others.
Peningkatan Keterampilan dan Perekonomian Masyarakat Pesisir Pulau Lemukutan melalui Pelatihan Pembuatan Snack Berbasis Rumput laut
Authors: Safitri Ikha , Warsidah  , Sofiana Mega Sari Juane , Yuliono Agus
Published: November 2021

The waters of Lemukutan Island have the potential of natural resources, including seaweed. Since 2011, Lemukutan Island has been the largest seaweed cultivation center in West Kalimantan. However, the Covid-19 pandemic has attacked all sectors and caused a decline in prices for fishery-based food commodities. This condition causes the farmers to suffer losses and the seaweed cultivation activity also decreases. Training on making snacks and seaweed jelly boba has been carried out to revive the economy of the coastal communities of Lemukutan Island. This activity involves all levels of the community through representatives of each RT using a hybrid method. Training is carried out with strict health protocols. This activity aims to improve the skills of coastal communities in processing seaweed-based foods. The training participants were very enthusiastic, from the presentation about the benefits of consuming seaweed for human health to the practice of making seaweed snacks and jelly.

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Perairan Pulau Lemukutan memiliki potensi sumber daya alam yang melimpah termasuk rumput laut. Sejak 2011, Pulau Lemukutan menjadi sentra usaha budi daya rumput laut terbesar di Kalimantan Barat. Namun, pandemi Covid-19 telah menyerang semua sektor kehidupan dan menyebabkan kemerosotan harga pada komoditas pangan berbasis perikanan. Kondisi ini mengakibatkan pembudi daya mengalami kerugian dan usaha budi daya rumput laut di Pulau Lemukutan juga menurun. Pelatihan pembuatan snack krenyes dan jelly boba rumput laut telah dilaksanakan untuk menumbuhkan kembali perekonomian masyarakat pesisir Pulau Lemukutan. Kegiatan ini melibatkan seluruh lapisan masyarakat Pulau Lemukutan melalui perwakilan tiap RT dengan metode hibrid. Pelatihan dilaksanakan dengan protokol kesehatan yang tegas. Kegiatan ini bertujuan untuk meningkatkan keterampilan masyarakat pesisir dalam mengolah makanan berbasis rumput laut. Peserta pelatihan sangat antusias mengikuti kegiatan, mulai dari pemaparan materi tentang manfaat dari mengonsumsi rumput laut bagi kesehatan manusia hingga praktik pembuatan snack dan jelly rumput laut.
Towards Effective Interpreter-Mediated Biblical Sermons in English and Kiswahili in the Tanzanian Charismatic and Pentecostal Churches: Any Challenge or Complexity Faced by the Church Interpreter?
Authors: Mlundi Dr. Simon
Published: November 2021

Interpretation is considered to be one of the most challenging professions in the world. This is due to its involvement of several abilities beyond language competence. Church interpretation is done predominantly by the untrained volunteering interpreters who in return, face a number of challenges. This paper examined the stakeholders’ perceptions towards the interpretation challenges facing the church interpreters by drawing examples from Charismatic and Pentecostal churches in the Tanzanian context. The study was conducted in Dar es Salaam, one of the largest commercial cities located in the Eastern Coastal regions of Tanzania in Africa. Data were collected through observation, interviews, questionnaires, and focus group discussions. It was found out that church interpreters encountered numerous challenges due to a lack of linguistic competence, experience, and professional training. Some of these challenges include; lack of enough biblical knowledge, difficulties in pronunciation, the use of difficult vocabulary, and poor preparations. It is recommended that church sermon interpreters should be provided with professional training in Translation and Interpretation Studies.
Determinantes de la precariedad del trabajo jornalero agrícola en México: un análisis histórico-institucional
Authors: Flores-Mariscal J. R. Joel
Published: November 2021

Objetivo: examinar las causas estructurales de la precariedad laboral de los trabajadores jornaleros agrícolas de México. Metodología: investigación cualitativa, histórico-sociológica a partir de la cual se identifican inercias históricas, institucionales y sociales que se convierten en condiciones determinantes de la estructura que produce la precariedad laboral de los jornaleros a pesar de las normas que deberían protegerlos. Resultados: se afirma que la desposesión agraria derivada de los procesos de colonización, la persistencia de una cultura económica de la explotación de los trabajadores, la marginalización política y la débil sindicalización de los jornaleros durante el periodo posrevolucionario en México, crearon las condiciones de precariedad de la ocupación. Valor: se subraya la importancia de descubrir herencias históricas como determinantes de las estructuras institucionales vigentes que afectan la calidad de vida de los trabajadores precarizados. Conclusiones: la revisión histórica sustenta el argumento de que para mejorar las condiciones laborales de los jornaleros agrícolas deben cambiarse ciertas instituciones políticas para que éstos obtengan representación política y normativas laborales específicas que modifiquen la concepción del trabajo agrícola manual, de forma tal que no sea considerado un segmento de disminución de costos de producción en detrimento de dichos trabajadores.
Finite Element Analysis of Gasket in Pressure Vessel
Authors: Jaishankara Sanjana
Published: November 2021

Abstract: Pressure vessel is a closed container designed to hold liquids or gases at a pressure which are higher than the surrounding atmospheric pressure. These pressure vessels are not made as a single component but manufacture with an assembly of many other components and connected through bolted joints or riveted joints or welded joints. These joints are susceptible to failure and cause leakage of the liquid or gas which are very dangerous and sometimes causes heavy loss of life, health and property. Hence proper care has to be taken during the design analysis processes by following ASME section VIII division 1 which specifies the design-by-formula approach while division 2 contains a set of alternative rules based on design by Analysis (FEA) to determine the expected deformation and stresses that may develop during operation. The ASME section-VIII division-2 standards are used for the design of pressure vessel. Leakage in gasketed flanged joints have always been a great problem for the process industry. The sealing performance of a gasketed flanged joints depends on its installation and applied loading conditions. The present project work involves the design procedure and stress analysis (Structural Analysis) for the leak proof pressure vessel at the gasket under three different gasket conditions. Keywords: 1. FEM, 2. ASME, 3. ANSYS, 4. Gasket,5. Displacement,6. Stress
Strengthening work engagement through digital engagement, gamification and psychosocial safety climate in digital transformation
Authors: Nurkhori Arief , Rahmatia Alfina , Handari Wahyuningsih Sri , Surwanti Arni
Published: November 2021

The problem faced in technological developments and during the pandemic is transforming employee habits from offline to online work engagement. This research aims to look at empirical evidence regarding the relationship between digital engagement, gamification, and psychosocial safety climate (PSC) on work engagement. This study employs a quantitative approach with structural equation modelling, analyzing a series of exploratory and confirmatory factors to determine the relationship between variables. This study uses primary data through a questionnaire of as many as 164 respondents with a purposive sampling technique. This study proves that digital engagement and gamification variables on PSC and work engagement have a significant positive effect. Aspects of digital transformation through digital engagement and gamification influence PSC to increase work engagement. The relationship between gamification channelled through PSC can also mediate and prove a positive influence in strengthening work engagement.
SANATTA İNSAN DOĞASININ ELEŞTİRİSİ
Authors: HAYKIR Mustafa
Published: November 2021

Bu çalışmada; resim, performans, sinema ve edebiyat gibi farklı sanat disiplinlerinde üretim yapan sanatçıların, insan doğasına dair düşüncelerinin eserlerine yansımaları incelenerek değerlendirilmektedir. Bu makalenin temel savlarından biri, insanın hem topluma ihtiyaç duyan hem de ondan kaçan bir varlık olarak mahkûm olduğu “sosyal varoluş paradoksu”nun ruhsal sorunlara yol açtığıdır. Sosyal etkileşim sürecinde oluşan benlik zedelenmeleri, filogenetik şiddet eğilimi ve kültürel sürecin oluşturduğu yıkıcı eğilimler, insan doğasının eleştirisi olarak sosyal deneylere ve sanata konu olmuştur. Sanata son derece eleştirel olarak yansıyan insanın doğası, fırsat oluştuğunda kötü, bencil, sadist, şiddete meyilli, fırsatçı olarak yansıtılmaktadır. Normal koşullarda toplumun uyumlu olarak görülen bireyleri yargılanmadıkları koşullarda her türlü kötülüğü yapacak düzeye gelmekte, yargılandığında ise masum rolü oynamaktadır. Savaşla yetinmeyip ölümü daha acılı hale getirmek için korkunç yöntemlere başvuran ve işkenceyi seyirlik bir malzeme haline getiren insanı eleştiren Callot; direnişçileri öldürmekle yetinmeyip onurlarını kırmak için türlü yönteme başvuran ve işledikleri dehşetten zevk alan askerleri eleştiren Goya; gücün bodrumlarda yarattığı dehşetle bir şeytana dönüştürdüğü maskenin ardındaki insanı gösteren Max Beckmann; hiçbir nedenleri olmadığı halde istediklerini yapma fırsatı verildiğinde işkenceye başvuran sıradan insanların görüldüğü Abramovic’in Ritim-0 performansı; dünyaya barış ve güveni yaymak isterken korkunç bir şekilde hayatına mal olan ‘Barış Gelini’ performansıyla Pippa Bacca; Yusuf Atılgan’ın, günün birinde bastırılmış duyguları tetikleyen bir kıvılcımla ortaya çıkan katili işlediği Zebercet karakterine; güçsüz iken bir soytarı gibi davranan güç kazandığında ise acımasız bir insana dönüşen insanı ele alan Dostoyevski’nin Stepançikovo Köyü ve Sakinleri; her türlü ihtiyacını karşılayan ablasına karşı canavarlaşan saf ve sakat bir insanın, emek ve fedakarlık karşısında nasıl empati duygusunu kaybettiğini anlatan Emile Zola’nın Toprak romanına; sahip olduğu gücü fark ettikçe kötüleşen ve çaresiz bir kurbanı alabildiğine sömüren insanı sert bir şekilde eleştiren Lars von Trier’in ‘Dogville’ filmi ile güven ihtiyacından dolayı topluma ihtiyaç duyan ama o topluma güven sağlamak için hiçbir şey yapmayan bencil insanın iki yüzünü gösteren Ruben Östlund’ın ‘Kare’, filmine kısaca değinilmektedir. Bu çalışmanın amacı sanatçıların insan doğasına dair sanata yansıtmak istedikleri düşüncelerin incelenerek anlaşılmasını sağlamaktır. Çalışmanın önemi sanatçıların vermeye çalıştığı mesajları sanatsal boyutlarıyla açıklığa kavuşturup, sanatçıların ve sanat yapıtlarının anlaşılmasını ve bu anlamda sanat literatürüne katkı sağlamaktır. Bu çalışma literatür taramasına dayalı eser incelemeyi baz alan bir çalışmadır.
Centros de fusión como instrumentos para intervenir el crimen organizado en entornos urbanos. Medellín 2018-2019
Authors: Londoño Hurtado Alejandro , Tobón Villada Andrés Felipe , Silva Díaz* Carlos Iván ,   Policía Nacional de Colombia
Published: November 2021

El presente capítulo tiene el objetivo de divulgar entre tomadores de decisiones y comunidad científica la experiencia del municipio de Medellín, Colombia, durante los años 2018-2019 en materia de intervención pública para contener la amenaza del crimen organizado, empleando para ello nuevos instrumentos de coordinación de actores en materia de priorización del problema y acción integrada bajo el modelo denominado centro de fusión. Para el análisis se empleó la metodología de buenas prácticas bajo el enfoque de sistematización de experiencias, obteniendo como resultados más relevan-tes la generación de sinergias operativas entre diferentes instituciones del nivel local y nacional, que condujeron a capturas estructurales e incautación de dinero y bienes afectando con ello la infraestructura operativa del crimen organizado, consiguiendo una reducción significativa de la violencia homicida.
PERILAKU HIGIENE PRIBADI TERHADAP KECACINGAN PADA MURID SDN MUARA PAGATAN UJUNG, KECAMATAN KUSAN HILIR KABUPATEN TANAH BUMBU
Authors: Hairani Budi , Annida Annida , Hariyati Erly , Andiarsa Dicky , Juhairiyah Juhairiyah
Published: November 2021

Penularan kecacingan pada anak usia sekolah dasar dapat terjadi dikarenakan perilaku higiene pribadi yang kurang baik. Salah satu kunci keberhasilan penanggulangan kecacingan adalah dengan memperbaiki perilaku higiene pribadi pada masyarakat terutama pada kelompok yang paling rentan tertular yaitu anak usia sekolah dasar. Penelitian ini bertujuan untuk mengetahui tingkat prevalensi kecacingan pada murid SDN Muara Pagatan Ujung serta mengidentifikasi faktor perilaku anak dalam menjaga kebersihan pribadi yang diduga berisiko terhadap penularan kecacingan. Penelitian dengan desain potong lintang dilakukan di SDN Muara Pagatan Ujung, Kecamatan Kusan Hilir Kabupaten Tanah Bumbu pada bulan Desember tahun 2016. Sampel merupakan total sampling dari seluruh populasi siswa SDN Muara Pagatan Ujung. Data yang dikumpulkan berupa hasil pemeriksaan feses dan hasil wawancara pada siswa.  Diketahui prevalensi kecacingan sebesar 13%. Hasil wawancara beberapa faktor perilaku higiene siswa terhadap kecacingan yang masih cukup tinggi yaitu tidak menggunakan alas kaki setiap keluar rumah (54%), tidak mencuci tangan dan kaki setelah bermain di tanah (47%) dan tidak mencuci tangan pakai sabun sebelum makan (50%). Perlu dilakukan edukasi pada siswa secara intensif mengenai pentingnya menjaga kebersihan pribadi terutama kebiasaan mencuci tangan dan kaki yang diiringi dengan pengadaan fasilitas pendukung kebersihan di sekolah seperti tempat cuci tangan dengan sabun dan adanya peraturan yang mengharuskan siswa untuk selalu memakai alas kaki.
HUBUNGAN SUMBER AIR MINUM DENGAN KEJADIAN DIARE DI PROVINSI SUMATERA SELATAN
Authors: Marini Marini , Ofarimawan Dheli , Ambarita Lasbudi P
Published: November 2021

Penyakit diare merupakan penyebab utama kedua kematian pada anak di bawah usia lima tahun di dunia dengan angka kematian sekitar 525.000 anak setiap tahunnya. Menurut data  Riskesdas 2018 diketahui bahwa prevalensi diare berdasarkan diagnosis tenaga kesehatan adalah sebesar 6,8%. Hal ini menunjukkan kenaikan 2,3% jika dibandingkan dengan hasil Riskesdas 2013 yaitu hanya 4,5%. Prevalensi diare untuk Provinsi Sumatera Selatan pada tahun 2018 sebesar 5,5%. Analisis ini bertujuan untuk melihat hubungan sumber air minum yang digunakan sehari-hari oleh masyarakat dengan angka kejadian diare di Provinsi Sumatera Selatan menggunakan hasil olah data dari Survei Sosial Ekonomi Nasional (Susenas) tahun 2018. Analisis yang digunakan adalah bivariat dengan korelasi pearson. Hasil analisis data menunjukkan adanya hubungan yang sangat erat antara sumber air minum air ledeng dengan kejadian diare dengan nilai R square sebesar 0,712 dan menunjukkan arah hubungan yang positif. Kesimpulan analisis ini menunjukkan bahwa angka kejadian diare berhubungan dengan penggunaan air ledeng sebagai sumber air minum. Promosi kesehatan berupa komunikasi, informasi dan edukasi (KIE) tentang pengelolaan sumber air untuk di konsumsi perlu terus digalangkan dalam upaya meningkatkan derajat kesehatan masyarakat.
GAMBARAN DISTRIBUSI SPESIES Anopheles DAN PERANNYA SEBAGAI VEKTOR MALARIA DI PROVINSI NUSA TENGGARA TIMUR, PAPUA DAN PAPUA BARAT
Authors: Mahdalena Vivin , Wurisastuti Tri
Published: November 2021

Malaria merupakan penyakit tular nyamuk yang masih menjadi penyebab utama kematian di negara berkembang. Malaria juga masih endemis di sebagian besar wilayah Indonesia, terutama di daerah Indonesia bagian Timur. Tiga provinsi di Indonesia dengan annual parasite incidence (API) tertinggi per 1000 penduduk pada tahun 2018 yaitu Nusa Tenggara Timur (NTT), Papua dan Papua Barat. Pengetahuan dan pemahaman mengenai nyamuk Anopheles sebagai vektor malaria di lokasi penyebarannya sangat penting dalam program intervensi pengendalian vektor malaria yang optimal. Artikel ini merupakan studi literatur dimana informasi diperoleh dari buku, artikel penelitian atau jurnal ilmiah, dan laporan hasil penelitian dari rentang tahun 2003 sampai tahun 2019. Anopheles yang ditemukan di Provinsi NTT, Papua dan Papua Barat yaitu An. vagus, An. barbirostris, An. subpictus, An. sundaicus, An. indefinitus, An. tesselatus, An. maculatus, An. aconitus, An. kochi, An. minimus, An. annularis, An. flavirostris, An. umbrosus, An. annulipes, An. farauti, An. barbumbrosus, An. ludlowae, An. punctulatus, An. aitkenii, An. longirostris, An. peditaeniatus, An. koliensis, An. bancrofti, An. hinesorum, dan An. meraukensis. Anopheles yang sudah terkonfirmasi sebagai vektor malaria yaitu An. barbirostris, An. subpictus, An. sundaicus, An. flavirostris, An. minimus, An. farauti, An. punctulatus dan An. longirostris. Perilaku kesukaan mengisap darah dari beberapa Anopheles yang menjadi vektor malaria lebih cenderung bersifat antropofilik.
School governance: Insights from the Italian case
Authors: Liberatore Assia
Published: November 2021

In view of the recent “La Buona Scuola” reform, growing attention is emerging about the enhanced role of the principal and its effects on school organizations in Italy. However, further research is needed to understand the Italian governance outcomes. Thereupon we would make a worthy contribution to the existing research with a deep assessment of Italian school governance. To achieve this purpose, the original contribution here is linking school governance to the learning outcomes of high school students and aspects of their daily life activities using a macroeconomic perspective. Our methodology is twofold: first, we review the various reforms of school governance in order to assess the strengths and weaknesses of each reform. Second, we involve a quantitative research methodology to analyze how school governance reflects social culture, students’ well-being, and educational outcomes. Our results confirm the significant role of the State in triggering education reform. Finally, we provide policy suggestions to the Italian Ministry of Education
The ecology and evolution of the Monito del monte, a relict species from the southern South America temperate forests
Authors: Fonturbel Francisco , Franco Marcela , Bozinovic Francisco , Quintero-Galvis Julian , Mejias Carlos , Amico Guillermo , Vasquez María Soledad , Sabat Pablo , Sanchez-Hernández Juan Carlos , Watson David , Saenz-Agudelo Pablo , Nespolo Roberto
Published: November 2021

The arboreal marsupial Monito del Monte (genus Dromiciops, with two
recognized species) is a paradigmatic mammal. It is the sole living
representative of the order Microbiotheria, the ancestor lineage of
Australian marsupials. Also, this marsupial is the unique frugivorous
mammal in the temperate rainforest, being the main seed disperser of
several endemic plants of this ecosystem, thus acting as keystone
species. Dromiciops is also one of the few hibernating mammals in South
America, spending half of the year in a physiological dormancy where
metabolism is reduced to 10% of normal levels. This capacity to reduce
energy expenditure in winter contrasts with the enormous energy turnover
rate they experience in spring and summer. The unique life-history
strategies of this living Microbiotheria, characterized by an
alternation of life in the slow and fast lanes, putatively represent
ancestral traits that permitted these cold-adapted mammals to survive in
this environment. Here we describe the ecological role of this
emblematic marsupial, summarizing the ecophysiology of hibernation and
sociality, actualized phylogeographic relationships, reproductive cycle,
trophic relationships, mutualisms, conservation and threats. This
marsupial shows high densities, despite presenting slow reproductive
rates, a paradox that is explained by the unique characteristics of its
three-dimensional habitat. We finally suggest immediate actions to
protect these locally abundant but globally threatened species.
AstraZeneca COVID-19 vaccine: A possible risk factor for Stroke, Case Series from Sudan
Authors: Omer Amira Siddig , Ahmed Abbasher Hussien Mohamed , Ahmed Khabab Mohamed , Abdallah Abdallah M. , Malekaldar Mohamed , Abbasher AlHussien , Abbasher Mohammed , Abbasher Abubaker Alsedig
Published: November 2021

Cerebrovascular accident (CVA) is one of the commonest neurological
deficits. There is a well-known association between COVID-19 and stroke.
We present a case series of Sudanese patients who developed CVA after
receiving the AstraZeneca COVID-19 vaccine suggesting a relationship
between the vaccine and CVA.
Event-related potentials reveal early visual-tactile integration in the deaf
Authors: Liu Siyi , Lu Aitao , Tian Haiping , Cai Yuexin , Zhang Meifang , Song Tianhua , Chen Guisheng , Qu Dianning
Published: November 2021

This study examined visual-tactile perceptual integration in deaf and normal hearing individuals. Participants were presented with photos of faces or pictures of an oval in either a visual mode or a visual-tactile mode in a recognition learning task. Event-related potentials (ERPs) were recorded when participants recognized real faces and pictures of ovals in learning stage. Results from the parietal-occipital region showed that photos of faces accompanied with vibration elicited more positive-going ERP responses than photos of faces without vibration as indicated in the components of P1 and N170 in both deaf and hearing individuals. However, pictures of ovals accompanied with vibration produced more positive-going ERP responses than pictures of ovals without vibration in N170, which was only found in deaf individuals. A reversed pattern was shown in the temporal region indicating that real faces with vibration elicited less positive ERPs than photos of faces without vibration in both N170 and N300 for deaf, but such pattern did not appear in N170 and N300 for normal hearing. The results suggest that multisensory integration across the visual and tactile modality involves more fundamental perceptual regions than auditory regions. Moreover, auditory deprivation played an essential role at the perceptual encoding stage of the multisensory integration.
A mixed boundary value problem of a cracked elastic medium under torsion
Authors: Kebli Belkacem , Madani Fateh
Published: November 2021

The present work aims to investigate a penny-shaped crack problem in the interior of a homogeneous elastic material under axisymmetric torsion by a circular rigid inclusion embedded in the elastic medium. With the use of the Hankel integral transformation method, the mixed boundary value problem is reduced to a system of dual integral equations. The latter is converted into a regular system of Fredholm integral equations of the second kind which is then solved by quadrature rule. Numerical results for the displacement, stress and stress intensity factor are presented graphically in some particular cases of the problem.
Stien i endring? Om det godes paradoks
Authors: Vistad Odd Inge
Published: November 2021

The trail is the most important helping measure in friluftsliv (i.e. outdoor recreation or OR), mainly since walking in the neighborhood or local forest is the most frequent friluftsliv activity. Historically, trails were linear structures through the landscape to help people move from A to B for various purposes, and generally a trail was the result of systematic trampling along a preferred durable route. In OR, the activity and the experiences along the trail are often regarded as more important than moving from A to B. Preference studies in Norway have shown that a narrow, simple, dirt trail through an open, mature forest is the most attractive type of trail. Developed, graveled and broader trails are visually less attractive, likewise for wooden boardwalks. Today, new trails and restored trails seem to be systematically developed, broadened and hardened with gravel, wooden boardwalks or a stone surface. And there are many good reasons for this, like limiting erosion and ground impact, stimulating OR volume and thereby public health, helping disabled persons to access nature, building attractions for tourists, stimulating new activities (like biking), maintaining OR access in built-up areas, etc. A new “trail normality” is on the way, and I see (potential) losses: The friluftsliv culture and human–nature relation are changing, and a “graveled nature” is likely to be less attractive for children. Constant trail maintenance is needed, which takes the attention away from high quality friluftsliv landscape and replaces it with friluftsliv infrastructure. A heavy responsibility rests on the responsible OR management authorities in balancing various OR and trail measures.
COMBINATION OF SEVERE DESTRUCTIVE SPONDYLITIS IN THE ONSET OF INFLAMMATORY BOWEL DISEASE IN A 13-YEAR-OLD ADOLESCENT
Authors:   Irkutsk Regional Children's Clinical Hospital, Irkutsk, Russia, Matyunova A.E. ,   Irkutsk State Medical Academy of Postgraduate Education, Branch of the Russian Medical Academy for Continuous Professional Education, Irkutsk, Russia, Kostik M.M. ,   Saint Petersburg State Pediatric Medical University, Saint Petersburg, Russia, Bregel L.V. ,   Irkutsk Regional Children's Clinical Hospital, Irkutsk, Russia,   Irkutsk State Medical Academy of Postgraduate Education, Branch of the Russian Medical Academy for Continuous Professional Education, Irkutsk, Russia
Published: November 2021

The paper presents a clinical case of severe destructive ankylosing spondylitis in a 13-year-old adolescent in combination with inflammatory bowel disease, in the onset of which serious functional limitations, high inflammatory activity and multiple erosive spinal injuries were revealed. The search for the causes of such an unusually of such an unusually severe course of spondyllitis after exclusion of infectious osteomyelitis, malignant neoplasms, non-bacterial osteomyelitis led to the discovery of asymptomatic ileocolitis, with a high degree of activity, massive ulcerative lesions of the ileum and colon, despite the complete absence of clinical gastrointestinal symptoms.
DIAGNOSTIC CRITERIA FOR VISCEROABDOMINAL DISPROPORTION SYNDROME IN GASTROSCHISIS
Authors:   Kuzbass Kemerovo Oblast Regional Children's Clinical Hospital named after Yu.A. Atamanov, Kemerovo, Russia, Plokhikh D.A. , Beglov D.E. ,   Kuzbass Kemerovo Oblast Regional Children's Clinical Hospital named after Yu.A. Atamanov, Kemerovo, Russia, Kovalkov K.A. ,   Kuzbass Kemerovo Oblast Regional Children's Clinical Hospital named after Yu.A. Atamanov, Kemerovo, Russia
Published: November 2021

The objectives of this study were to determine the frequency and search for additional criteria for the diagnosis of visceroabdominal disproportion syndrome (VADS) in newborns with gastroschisis. Materials and methods of research: prospective controlled observational cross-sectional analytical study was carried out in 61 newborns with gastroschisis, admitted from June 2009 to July 2021. To search for the most significant factors indicating the presence of VADS, the following parameters were recorded in the studied patients: the size of the defect in the anterior abdominal wall, the composition of eventrated organs, the presence of a conglomerate of intestinal loops, the diameter of the intestinal tube, the thickness of the intestinal wall, the degree of visceroabdominal disproportion (VAD). Results: VAD was detected in 50 (82%) newborns with gastroschisis. In 10 (17%) cases, VAD was mild, in 27 (44%) – moderate, and in 13 (21%) patients – severe. A moderate direct relationship was found between the size of the anterior abdominal wall defect (r=0.29, p=0.022), intestinal tube diameter (r=0.56; p=0.001) and the severity of VAD. There was a strong direct correlation between the thickness of the intestinal wall, and the frequency and severity of VAD (r=0.93, p=0.001). A direct association was found between the presence of a conglomerate of intestinal loops in the eventrated organs and the frequency of VAD (p=0.002). There was no statistically significant relationship between the number of eventrated anatomical structures with the frequency and degree of VAD (p=0.36). Conclusion: to determine VADS, it is advisable to diagnose the following pathological conditions in patients with gastroschisis: thickening of the intestinal wall, dilatation of the intestinal tube, the presence of a conglomerate of tightly welded eventrated organs, the severity of which is directly proportional to the degree of disproportion.
NEONATAL LISTERIOSIS: AN ALMOST FORGOTTEN INFECTION OR RENAISSANCE OF THE DISEASE
Authors:   Petrozavodsk State University (PetrSU), Petrozavodsk, Republic of Karelia, Russia, Gumeniuk E.G. , Ukvalberg M.E. ,   Petrozavodsk State University (PetrSU), Petrozavodsk, Republic of Karelia, Russia
Published: November 2021

Maternal neonatal listeriosis is less common desease, but contributes significantly to neonatal and infant mortality rates. The survey presents data on the the pathogen, epidemiology of the disease, and risk factors. Attention is paid to the pathogenesis of the development of this intrauterine infection. The emphasis is placed on the development of neonatal (congenital) listeriosis, as well as the risk of serious complications for the child. The article describes the symptoms of the disease at early and late manifestation, variants of the clinical course, the results of autopsy of dead newborns. Attention is drawn to the problems of treatment and prevention of neonatal listeriosis. Doctors of related specialties (obstetricians-gynecologists, neonatologists, pediatricians) should have up-to-date information about this disease.
11 de setembro: das Reformas aos atentados
Authors: Santos Karolina dos
Published: November 2021

O presente artigo pretende mostrar as ideias e acontecimentos que serviram de base ao líder da Al-Qaeda Osama bin Laden. Através da Escola Hanbali e das Reformas no mundo islâmico, surgiram teóricos que são peças fundamentais para entender os desdobramentos de grupos como a Al-Qaeda. Dessa forma, o artigo se debruça sobre os aspectos históricos e religiosos que perpassam esse meio. Através das obras do teórico Sayyid Qutb, faz-se uma abordagem a respeito do conceito de jihad, sobre o seu significado e como a questão é abordada pela Al-Qaeda.
Experience in fostering regional collaboration and Coordination to use data for battling infectious diseases in sub-Saharan Africa
Authors: Arunga Geoffrey , Ca Tome , Odero Patricia , Bashir Ahmed , Manituo Somda Serge , Adan Fatuma , Weiss Martin , Naidoo Wayne , Adjei Benin Frank , Malone Todd , A. LeGrand Christopher , Yona Kitua Andrew
Published: November 2021

The emergence of COVID-19 highlights globalisation realties, where diseases may emerge from anywhere and rapidly spread globally. Lessons emphasise the necessity for strengthening regional and global collaboration and coordination to allow rapid risk identification, resource mobilisation and joint actions. We report the experience of the Regional Action through Data (RAD) partnership in fostering regional cooperation and collaboration to use data for battling infectious diseases and the effects of COVID-19. The Partnership comprised;BoadReach company, The West African Health Organization (WAHO) and the Intergovernmental Authority on Development (IGAD); Duke University Global Health Centre and the Jembi Health Systems, South Africa. Main objective: To address the problem of limited used of data to drive performance in healthcare service delivery in sub-Saharan Africa; by changing how and why data is collected, analysed, and then used to achieve results. Specific objectives: 1. Regional level: To equip and empower IGAD and WAHO with evidence-based analytics to drive data use for evidence-based policy and program action in public health (regional level). 2. Patient -provider level: To deploy and implement a digital health solution for child-hood vaccination services focused on mobile cross-border populations along the Uganda-Kenya border. Engagement approaches used included; meetings, workshops, technical working groups, establishing monitoring system and annual implementation revision. Targeted training and capacity building were conducted. All activities were built on existing systems and structures to strengthen ownership and sustainability. Regional level achievements: 1. Regional health data sharing and protection policy, 2. Strengthened regional health information platform. Patient provider level: Deployment of a cloud based digital health solution to enhance childhood access to vaccination services for cross border populations of Kenya and Uganda, 3. Both regions developed resource mobilisation plans for sustainability. RAD established the foundation for building trust and strengthening regional collaboration and coordination in health in Sub-Saharan Africa.