bluuebunny/crossref_metadata_2025 huggingface dataset:
Jumlah eritrosit, hemoglobin dan hematokrit pada tikus (Rattus norvegicus) yang diberi seduhan kopi arabika (Coffea arabica)
Authors: Dewi Lolita Sintia , Yulihastuti Dwi Ariani , Wijana I Made Sara , Narayani Inna
Published: March 2024

Arabica coffee (Coffea arabica) contains tannins and caffeine which will interfere with iron absorption and cause anemia. This study aims to determine the number of RBC (Red Blood Cell) or erythrocytes blood hemoglobin levels and the percentage of PCV (Packed Cell Volume) or hematocrit in rats (Rattus norvegicus) treated with arabica coffee brew (Coffea arabica L). The method used is RAL (Completely Randomized Design) in 5 treatment groups and each group contains 5 rats. Group 1 as control by giving 3,6 mL of distilled water. Group 2 as the first treatment (P1) by giving 3,6mL of brewed coffee powder dose of 150mg/200gBB, group 3 as the second treatment (P2) by giving 3,6mL of brewed coffee powder dose of 310mg/200gBB, group 4 as the third treatment (P3) by giving 3.6mL of brewed coffee powder dose 630mg/200gBB and group 5 as the fourth treatment (P4) by giving 3,6mL of brewed coffee powder dose of 1,260mg/200gBB. The method of steeping coffee with oral gavage is using an oral sonde. Data were analyzed using Analysis of Variance (ANOVA). The results obtained in this study were that brewed arabica coffee (Coffea arabica) did not have a real effect on the number of erythrocytes, hematocrit percentage and hemoglobin levels in rats (Rattus norvegicus) because caffeine and tannin levels that act as iron inhibitors have been reduced due to high temperatures in the roasting process. Caffeine levels in coffee samples have not affected iron absorption. Iron reserves in the body are still in a normal state so that they do not affect the process of erythropoiesis.
CERDIK DALAM MENURUNKAN TEKANAN DARAH PADA PENDERITA HIPERTENSI
Authors: Dewiyulian Dewiyuliana
Published: March 2024

Kasus hipertensi semakin meningkat setiap tahunya di dunia. Hipertensi disebabkan olah faktor keturunan, jenis kelamin, usia, gaya hidup yang tidak sehat, merokok, konsumsi garam berlebih dan stress. Hipertensi yang tidak diatasi dalam waktu yang lama dapat menyebabkan kerusakan pada sistim kardiovaskuler, serangan jantung, stroke, gagal ginjal dan menyebabkan terjadinya kematian. Hipertensi dapat diturunkan dan dikontrol melalui manajemen dan intervensi yang tepat serta terpadu. CERDIK merupakan salah satu program dari pemerintah dalam pencengahan dan menanggulagi tekanan darah melalui kegiatan yang dilakukan secara mandiri oleh penderita hipertensi maupun bersama-sama dengan melibatkan keluarga dan anggota masyarakat.  Penelitian ini bertujuan untuk mengetahui pengaruh CERDIK dalam menurunkan tekanan darah pada penderita Hipertensi. Penelitian merupakan penelitian quasi eksperimen design dengan rancangan Two group post test Design. Populasi dalam penelitian ini adalah seluruh masyarakat yang mengalami Hipertensi dengan jumlah masing-masing sampel sebanyak 9 orang di kelompok intervensi dan 9 orang responden di kelompok kontrol, menggunakan tehnik purposive sampling. Pelaksanaan CERDIK diberikan setiap 1 minggu sekali selama satu bulan. Pengujian hipotesis menggunakan uji t test Independent dengan tingkat kemaknaan ? =0,05. Hasil penelitian menunjukkan adanya penurunan tekanan darah setelah pemberian intervensi CERDIK. Maka diharapkan kepada petugas kesehatan, masyarakat dan keluarga mengaplikasikan CERDIK dalam mengatasi dan mengontrol tekanan darah.
THE EFFECT OF DIRECT INSTRUCTIONAL TRAINING MODEL ON BREASTFEEDING PREPARATION KNOWLEDGE AND SKILLS IN PREGNANT WOMEN AT IDAMAN PADANG CLINIC
Authors: Amna Fitra Afrida
Published: March 2024

Latar Belakang: Persiapan menyusui merupakan pengetahuan dan keterampilan pada ibu hamil untuk memberikan ASI pada bayi tanpa tambahan makanan atau minumam apapun kecuali obat dan vitamin, selama 6 bulan berturut-turut. Kasus rendahnya pengetahuan dan keterampilan persiapan menyusui pada ibu hamil setiap tahun meningkat. Berdasarkan  Data  dan  Informasi  Profil  Kesehatan Indonesia tahun 2022 cakupan ASI Eksklusif meningkat menjadi 55,4 % namun data dari Dinkes Kota Padang tahun 2022 angka cakupan ASI Eksklusif sebesar 73,7%. Hal ini jauh dibawah target nasional sebesar 80%. Persiapan  pemberian  ASI sebaiknya  mulai  dilakukan saat  ibu hamil  secara fisik dengan  cara  memperhatikan  nutrisi,  istirahat  cukup,  serta  mempersiapkan  payudara  dengan melakukan perawatan payudara. Persiapan secara psikologis dengan meyakini bahwa dirinya siap untuk menyusui, mampu menghasilkan ASI yang cukup untuk bayinya serta mendapat dukungan dari  lingkungan  sekitar  dan  petugas  kesehatan. Tujuan: Untuk meningkatkan pengetahuan dan keterampilan ibu hamil tentang persiapan menyusui menggunakan model Pelatihan Direct Instructional yang merupakan salah satu cara untuk meningkatkan pengetahuan dan keterampilan ibu hamil tentang persiapan menyusui, agar ibu hamil memiliki pengetahuan dasar untuk menghasilkan ASI yang baik. Metode: Penelitian ini menggunakan quasi ekperimen. Data menggunakan kuisioner dan lembar observasi. Uji statistik menggunakan uji t-test. Analisis data disajikan untuk mengambarkan Pengaruh Pelatihan Model Direct Instructional Terhadap Pengetahuan dan Keterampilan Ibu Hamil tentang Persiapan Menyusui Di Klinik Idaman Kota Padang. Hasil: Hasil penelitian menunjukkan bahwa, ada perbedaan pengetahuan dan keterampilan ibu hamil dalam mempersiapkan diri menyusui setelah diberikan pelatihan direct instructional (p = 0.000). Kesimpulan: Penelitian diharapkan dapat memberikan manfaat secara langsung dengan meningkatkan pengetahuan dan keterampilan ibu hamil dalam mempersiapkan diri untuk menyusui sebelum melahirkan, serta meningkatkan angka pemberian ASI eksklusif pada bayi di Indonesia.
Effect of Phytogenic Additive on the Quality, Composition and Production of Cows' Milk
Authors: Fantini Wesllei , Fraga Denize da Rosa , Teixeira Khauana Sauzer , Trada Ana Laura , Hörz Sabrina Nascimento , Villani Juliana Menegol , Secco Tadine Raquel , Sabadini Priscila Batista , Libardoni Felipe
Published: March 2024

Objective: To evaluate the effect of the natural nutritional additive based on phytogenic compounds Rumetan® on the production, composition and quality of milk from dairy cows and its effect on the metabolic health of the animals.
 
Theoretical framework: Research indicates the potential for using phytogenic additives in the diet of lactating cows as a sustainable alternative to improve milk production and quality, but studies that prove the effects of these products when combined are necessary.
 
Methodology: The study involved 20 Holstein cows. The composition was evaluated (Fat, Protein, Lactose, Total Solids); Somatic Cell Count (SCC) and Milk Urea Nitrogen (NUL) in addition to blood glucose and urea levels, milk production in liters, milk production corrected for 4% fat. Comparisons were made between two groups for ninety days: one group that received the phytogenic additive at a dose of 50 grams of animal/day mixed with the diet and the other did not receive it.
 
Results and Conclusion: The use of the phytogenic additive increased the milk production of cows without affecting the solids composition and reduced the somatic cell count.
 
Implications of the research: The study advances in relation to having a phytogenic additive as a sustainable alternative for animal nutrition, which improves the production and quality of milk.
 
Originality/value: The experiment is a pioneer in presenting the use of this phytogenic additive for lactating cows.
 
Keywords: Milk Quality, Phytogenic Additives, Dairy Cows, Nutrition.
Building the methodological bases to assess tax losses of the budget from illegal labor activities of foreign migrants
Authors: KHRUSTALEV Evgenii Yu. , GREBENKINA Svetlana A.
Published: March 2024

Subject. The article addresses illegal activities of illegal foreign labor force.
Objectives. The aim is to create a comprehensive methodology for assessing the tax losses of the State from illegal labor activities of external migrants.
Methods. The theoretical and methodological basis of the study include the fundamental factors of the theory of taxation and economic security, scientific works by specialists in the field of illegal migration. We employed methods of theoretical and empirical cognition, in particular, systems analysis and synthesis, analogies, classification, statistical methods, comparison and system-structural analysis, expert assessment.
Results. We analyzed the features of tax deductions of external labor migrants, the specifics of their employment depending on the country of arrival, and statistical data on migration flows. The paper identified the key risks of illegal employment of non-residents. We proposed a methodology for assessing potential tax losses from illegal migrant labor, and confirmed the reliability and effectiveness of the methodology through testing.
Conclusions. The findings can be used to determine the effectiveness of implemented migration and tax policies, serve as a guideline for possible adjustments of control and supervisory measures to ensure the economic security of the State.
Soft Skills for Employment in Morocco: A Value Over or Equal to the Technical Know-how?
Authors: Ezzaidi Mohamed
Published: March 2024

Soft skills comprise a blend of social abilities, interpersonal communication, knowledge, and character traits that enhance individuals' social and professional lives. Beyond technical expertise, soft skills are widely recognized for significantly improving employability prospects and aiding job candidates in enhancing their competitiveness during job hunting and career development. While some research projects suggest that technical knowledge is less crucial than soft skills in job interviews, other scholars argue for an equal emphasis on both to craft a comprehensive job applicant profile. This paper investigates this topic from a three-pronged perspective. First, it explores the extent to which soft skills overshadow technical knowledge in the eyes of employers in the Moroccan job market. Second, it assesses the level of engagement of Moroccan university students in learning and acquiring soft skills. Finally, it underscores the role of higher education teachers in cultivating soft skills through their instruction. This study is an exploratory endeavor that utilizes secondary data sources from scientific journals and administers questionnaires to teachers, enterprise managers, and students to unveil their attitudes in the Moroccan context. The results reveal some disparities between the existing literature and the situation in Morocco. It appears that the interest in soft skills in Morocco is still influenced more by personal and functional variables than institutional recommendations.
Dynamic MPFL reconstruction using a combination of adductor sling technique and basket weave method – A retrospective cohort study eliciting the functional results in an Indian population
Authors: Kedia Rishabh , Basumallick Manabendra Nath , Khan Imran
Published: March 2024

Objectives:

The medial patellofemoral ligament (MPFL) is one of the primary stabilizers of the patella. It resists lateral Mal-tracking of the patella and keeps the patella centered within the patellofemoral groove. MPFL reconstruction is a common and widely used procedure to treat lateral patellar instability. Most conventional techniques of MPFL reconstruction use bony tunnels in the medial femoral condyle and patella to create a static construct, which has its own set of issues. This article is aimed at describing early results from our technique for bone-sparing implant-less MPFL reconstruction with a dynamic construct using semitendinosus graft.

Materials and Methods:

This was a retrospective and single-center study of ten symptomatic patients between 12 and 35 years of age with a primary event to surgery gap of a mean of 49.6 months with a history of pain and patellar instability diagnosed by clinical and radiological means between January 2020 and August 2022. MPFL reconstruction was performed using semitendinosus graft passing under the adductor longus tendon close to its insertion and fixed at the patella with Vicryl No. 2 sutures through proximal and distal tails, respectively.

Results:

The pre-operative and follow-up mean Kujula scores were 57.5 ± 5.91 and 87 ± 4.06 (P < 0.0001), respectively, which showed significant improvement. All patients gained adequate patellar stability. No incidence of patella fracture was noted. There were no post-operative complications related to the procedure.

Conclusion:

Our study shows promising results and tries to augment the medial restraint by making the MPFL dynamic in nature, which tightens in flexion and relaxes in extension through the adductor sling at the femoral end and the basket weave technique at the patellar end. It avoids implant and bony tunnel-related complications and is simple and cost-effective.
The Karelian Arctic in the directions of China’s Arctic policy at the present stage
Authors: Pitukhina M. A. , Belykh A. D.
Published: March 2024

The article identifies four main areas that define China’s strategic goals in the Arctic region: the energy sector, infrastructure, tourism, educational and scientific co-operation. Special attention is paid to the strategic friendship between Russia and China in the context of Arctic policy. The RussianChinese partnership in this region is seen as a key factor in ensuring the stability and development of Russia’s Arctic zone. The interaction between the two countries not only contributes to the strengthening of economic ties, but also ensures the security and sustainable development of the region. The paper presents examples of successful cooperation between the Republic of Karelia and the People’s Republic of China and analyses these relations as an example of the practical implementation of China’s Arctic strategy at the regional level. It is important to note that the realisation of many investment projects on exploration and mining in the Karelian Arctic is connected with the attraction of Chinese investment in this industry. The article also evaluates Chinese interests in the Karelian Arctic in other areas, such as the construction of hydroelectric power station infrastructure projects in the Kemsky region as well as some perspective projects related to the construction of a deep-sea port in Kem or a seaport in Belomorsk.
Features of the development of women's prose in English-language literature
Authors: Мурадова А.К. , Газимаева Х.А.
Published: March 2024

В данной статье рассматриваются особенности развития женской прозы в странах англоязычного мира на протяжении нескольких столетий. Автор анализирует этапы становления и развития жанра, выделяя при этом ключевые периоды и направления, оказавшие существенное влияние на формирование национальных литературных традиций. При изучении материалов были проанализированы сотни произведений различных авторов, начиная со времен Средневековья и заканчивая современностью. Данные о популярности и востребованности книг были получены путем изучения статистики продаж, отзывов критиков и мнений читательской аудитории. Также был проведен анализ научных исследований в области гендерных аспектов литературы. Полученные результаты свидетельствуют о постепенном расширении тематического и стилистического спектра произведений авторов-женщин, а также об интеграции их творчества в культурное пространство зарубежных стран. Исследование жанра женской прозы позволяет сделать еще несколько важных теоретических обобщений. Так, нельзя не отметить созидательную роль конкуренции между авторами в стимулировании поиска новых форм и способов выразительности. Постоянное соперничество за внимание читательской аудитории побуждало писательниц к творческим экспериментам, расширяя тематические и стилистические границы жанра.

This article examines the features of the development of women's prose in the countries of the English-speaking world over several centuries. The author analyzes the stages of formation and development of the genre, highlighting key periods and trends that had a significant impact on the formation of national literary traditions. When studying the materials, hundreds of works by various authors were analyzed, from the Middle Ages to the present. Data on the popularity and demand of books was obtained by studying sales statistics, reviews from critics and opinions of the readership. An analysis of scientific research in the field of gender aspects of literature was also carried out. The results obtained indicate a gradual expansion of the thematic and stylistic range of works by female authors, as well as the integration of their work into the cultural space of foreign countries. The study of the genre of women's prose allows us to make several more important theoretical generalizations. Thus, one cannot fail to note the creative role of competition between authors in stimulating the search for new forms and methods of expression. Constant competition for the attention of the readership encouraged writers to experiment creatively, expanding the thematic and stylistic boundaries of the genre.
Features of the university’s investment policy in the context of public-private partnership
Authors: Арсаханова З.А.
Published: March 2024

В настоящее время система государственно-частного партнерства выступает одной из ключевых форм взаимодействия государства и бизнеса в сфере образования. Однако ряд специфических особенностей инвестиционной политики высших учебных заведений при реализации данного взаимодействия остается недостаточно изученным. Цель данной статьи состоит в теоретическом осмыслении и практическом анализе основных принципов и механизмов формирования инвестиционной политики вуза в условиях государственно-частного партнерства с учетом специфики отрасли. Материалы: отчеты 2 вузов о реализации проектов ГЧП за период 2018-2022 гг, данные опроса руководителей 20 вузов о приоритетах инвестиционной политики. Методы: сравнительный анализ, статистический анализ, анкетирование, метод экспертных оценок. Результаты: выявлены основные приоритеты инвестиционной политики вузов в условиях развития партнерства с бизнесом; изучены наиболее эффективные подходы к формированию инвестиционных программ вузов. Вместе с тем необходимо отметить, что при формировании инвестиционной политики необходим учет не только количественных, но и качественных показателей. Так, помимо объемов привлеченных инвестиций и их структуры целесообразно анализировать соответствие инвестиционных проектов запросам рынка труда и степень их влияния на инновационную активность университетов.

Currently, the public-private partnership system is one of the key forms of interaction between the state and business in the field of education. However, a number of specific features of the investment policy of higher educational institutions in the implementation of this interaction remain insufficiently studied. The purpose of this article is to provide a theoretical understanding and practical analysis of the basic principles and mechanisms for developing a university’s investment policy in the context of a public-private partnership, taking into account the specifics of the industry. Materials: reports from 2 universities on the implementation of PPP projects for the period 2018-2022, data from a survey of heads of 20 universities on investment policy priorities. Methods: comparative analysis, statistical analysis, questionnaires, expert assessment method. Results: the main priorities of the investment policy of universities in the context of developing partnerships with business were identified; the most effective approaches to the formation of investment programs of universities have been studied. At the same time, it should be noted that when forming an investment policy, it is necessary to take into account not only quantitative, but also qualitative indicators. Thus, in addition to the volume of attracted investments and their structure, it is advisable to analyze the compliance of investment projects with the demands of the labor market and the degree of their influence on the innovative activity of universities.
Development and testing of interdisciplinary methods of teaching foreign languages in universities
Authors: Абдукадырова Т.Т. , Арсалиева Э.Х.
Published: March 2024

В настоящее время проблема развития взаимодействия различных сфер знаний и междисциплинарного подхода к обучению является весьма актуальной в современном образовательном пространстве высшей школы. Данное исследование посвящено исследованию возможностей разработки новых подходов к изучению иностранных языков путем интеграции лингвистических знаний с данными естественных и гуманитарных наук. Была осуществлена апробация программы по изучению английского языка, включающей изучение лексического материала, связанного с естествознанием и медицинскими терминами. В ходе опытно-экспериментальной работы 60 студентов первого курса биолого-химического факультета ЧГУ им. А. А. Кадырова была оценена эффективность разработанной методики обучения иностранному языку на основе межпредметных связей. Цель данного исследования заключалась в разработке и апробации методики обучения английскому языку для студентов естественнонаучного вуза на основе использования межпредметных связей. В качестве экспериментальной базы в качестве экспериментальной базы для апробации предлагаемой методики был выбран учебный процесс кафедры биологии одного из ведущих университетов страны. Для дополнительной характеристики особенностей усвоения лексического материала студентами экспериментальной и контрольной групп был проведен анализ скоростных показателей распознавания терминов на завершающем этапе обучения.

Currently, the problem of developing the interaction of various fields of knowledge and an interdisciplinary approach to learning is very relevant in the modern educational space of higher education. This study is devoted to exploring the possibilities of developing new approaches to learning foreign languages by integrating linguistic knowledge with data from the natural sciences and humanities. A program for learning English was tested, including the study of lexical material related to natural science and medical terms. During the experimental work, 60 first-year students of the Faculty of Biology and Chemistry of ChSU named after. A. A. Kadyrov assessed the effectiveness of the developed methodology for teaching a foreign language based on interdisciplinary connections. The purpose of this study was to develop and test a methodology for teaching English to students at a natural science university based on the use of interdisciplinary connections. The educational process of the biology department of one of the leading universities in the country was chosen as an experimental base for testing the proposed methodology. To further characterize the characteristics of the assimilation of lexical material by students of the experimental and control groups, an analysis of speed indicators of term recognition at the final stage of training was carried out.
The quality of economic and organizational conditions for the implementation of secondary vocational education programs: analysis of the opinions of participants in educational relations
Authors: Пунанцев А.А. , Аминова С.В.
Published: March 2024

Представленное в данной статье исследование направлено на частичное решение проблемы поиска научно-методического обоснования действий по выработке мер, обеспечивающих выполнение экономико-организационных условий реализации образовательных программ среднего профессионального образования. Изложены результаты апробации данного обеспечения в Мурманской области. На основе проанализированных и обобщенных результатов апробации разработанного научно-методического обеспечения решений в сере обеспечения качества экономико-организационных условий реализации образовательных программ среднего профессионального образования можно сделать вывод, что обучающиеся и родители (законные представители) несовершеннолетних студентов СПО встречаются с необходимостью дополнительных расходов на обучение в профессиональных образовательных организациях. Вместе с тем очевидно, что в дальнейшем требует уточнения содержание понятия «обязательная часть программы» в представлении регионального сообщества, так как полученные результаты с известной долей уверенности позволяют предположить, что видение данного понятия субъектами образовательного процесса отличается от четко дефинированного смыслового наполнения этого термина в нормативных правовых актах. Проведение просветительских мероприятий соответствующей тематики, в том числе направленных на повышение юридической грамотности населения в этой сфере, позволило бы решить эту проблему.

The research presented in this article is aimed at partially solving the problem of finding a scientific and methodological justification for actions to develop measures that ensure the fulfillment of economic and organizational conditions for the implementation of educational programs of secondary vocational education. The results of testing this software in the Murmansk region are presented. Based on the analyzed and generalized results of testing the developed scientific and methodological support for solutions in ensuring the quality of economic and organizational conditions for the implementation of educational programs of secondary vocational education, it can be concluded that students and parents (legal representatives) of minor students of secondary vocational education are faced with the need for additional expenses for training in vocational educational organizations. At the same time, it is obvious that in the future the content of the concept “mandatory part of the program” in the view of the regional community requires clarification, since the results obtained with a certain degree of confidence suggest that the vision of this concept by the subjects of the educational process differs from the clearly defined one the semantic content of this term in regulatory legal acts. Carrying out educational events on relevant topics, including those aimed at increasing the legal literacy of the population in this area, would help solve this problem.
Cross-cultural analysis of vocal education: comparison of singing teaching methods in different cultures
Authors: Шаокай С.
Published: March 2024

В настоящее время проблема сравнительного анализа подходов к вокальному образованию в разных культурах является крайне актуальной. Цель данного исследования заключалась в сопоставлении методик обучения пению в России, Италии, Германии и Японии на основе изучения исторических источников и современной научной литературы по вокальному искусству. Проблема изучения национальных особенностей методик обучения вокальному искусству в различных культурах является в высшей степени злободневной с учетом глобальных процессов интеграции и взаимопроникновения цивилизационных традиций. Несомненно, понимание специфики подходов к формированию вокальной техники в конкретных странах позволит глубже осмыслить природу национальных школ пения и разработать более эффективные методы обучения с учётом индивидуальных особенностей учеников. Материалами для исследования послужили научные труды по методике вокального образования Г.B. Страдалли, Ф. Ламперти, Ц. Манцони, Х. Лиссауэра и др., а также учебные программы ведущих консерваторий стран выборки. Было выявлено, что несмотря на определенные отличия в подходах, все рассматриваемые школы базируются на общих принципах формирования вокальной техники: от работы над дыханием и резонансом до совершенствования артистического мастерства. Однако существуют и национальные особенности методик, обусловленные культурными традициями.

Currently, the problem of comparative analysis of approaches to vocal education in different cultures is extremely relevant. The purpose of this study was to compare the methods of teaching singing in Russia, Italy, Germany and Japan based on the study of historical sources and modern scientific literature on vocal art. The problem of studying national peculiarities of vocal art teaching methods in various cultures is highly topical, taking into account the global processes of integration and interpenetration of civilizational traditions. Undoubtedly, understanding the specifics of approaches to the formation of vocal technique in specific countries will allow us to better understand the nature of national singing schools and develop more effective teaching methods taking into account the individual characteristics of students. The materials for the study were scientific works on the methodology of vocal education by G.B. Stradalli, F. Lamperti, C. Manzoni, H. Lissauer, etc., as well as curricula of leading conservatories in the sample countries. It was revealed that despite certain differences in approaches, all the schools under consideration are based on the general principles of vocal technique formation: from working on breathing and resonance to improving artistic skills. However, there are also national peculiarities of the methods due to cultural traditions.
Individualization in the technologies of teaching sports disciplines
Authors: Кубасов Ю.А.
Published: March 2024

Введение. В настоящее время одной из наиболее актуальных задач российской системы высшего образования является повышение эффективности подготовки студентов, что во многом предполагает переориентацию на индивидуализацию образовательного процесса. Данная тенденция нацелена на максимальный учёт особенностей каждого обучающегося и охватывает не только гуманитарные дисциплины, но и сферу физической культуры и спорта. Материалы и методы. Для всестороннего исследования проблемы были проведены анкетирование 65 студентов и 5 преподавателей факультета физической культуры и спорта одного из ведущих педагогических университетов Центрального федерального округа России, а также детальный анализ более 50 научных работ российских и зарубежных учёных по данной тематике. Методы исследования включали статистическую обработку полученных в результате опросов данных с помощью пакета SPSS и проведение полуструктурированных интервью с 8 респондентами. Результаты. Было выявлено, что лишь 37% респондентов удовлетворены качеством обучения, 68% преподавателей поддерживают идею индивидуализации. Анкетирование показало, что 53-61% студентов и 80% педагогов считают целесообразным выделение 30-40% учебного времени на занятия по индивидуальным планам. Полученные результаты обосновывают необходимость разработки и внедрения модели обучения, предусматривающей индивидуальные образовательные траектории у каждого студента с учётом его особенностей для повышения эффективности усвоения знаний.

Introduction. Currently, one of the most urgent tasks of the Russian higher education system is to increase the effectiveness of student training, which in many ways implies a reorientation towards the individualization of the educational process. This trend is aimed at maximizing the consideration of the characteristics of each student and covers not only the humanities, but also the field of physical culture and sports. Materials and methods. For a comprehensive study of the problem, a survey was conducted of 65 students and 5 teachers of the Faculty of Physical Culture and Sports of one of the leading pedagogical universities of the Central Federal District of Russia, as well as a detailed analysis of more than 50 scientific papers by Russian and foreign scientists on this topic. The research methods included statistical processing of survey data using the SPSS package and conducting semi-structured interviews with 8 respondents. Results. It was revealed that only 37% of respondents are satisfied with the quality of education, 68% of teachers support the idea of individualization. The survey showed that 53-61% of students and 80% of teachers consider it advisable to allocate 30-40% of the study time to classes according to individual plans. The results obtained substantiate the need to develop and implement a learning model that provides for individual educational trajectories for each student, taking into account his/her characteristics, in order to increase the effectiveness of knowledge acquisition.
Direct catalytic photodecarboxylative amination of carboxylic acids with diazirines: Divergent access to amines, hydrazines, and nitrogen-containing heterocycles
Authors: Maharaj Vishala , Athawale Paresh , Chandrachud Preeti , Lopchuk Justin
Published: March 2024

Amines, hydrazines, and nitrogen-containing heterocycles are pivotal species in medicine, agriculture, fine chemicals, and materials. Diazirines have been recently reported to serve as versatile electrophilic amination reagents for the synthesis of building blocks or late-stage C–N bond formation. Here we report the catalytic photodecarboxylative amination of carboxylic acids with diazirines under mild conditions. The substrate scope includes broad functional group tolerance, such as ketones, esters, olefins, and alcohols, along with the late-stage amination of naproxen, ibuprofen, gemfibrozil, and gibberellic acid. Synthetic applications leverage the versatility of the intermediate diaziridines and include the regioselective preparation of a suite of 1H-indazoles, 2H-indazoles, and fluoroquinolones.
An Unusual Ferryl Intermediate and its Implications for the Mechanism of Oxacyclization by the Loline-Producing Iron(II)- and 2-Oxoglutarate-Dependent Oxygenase, LolO
Authors: Pan Juan , Wenger Eliott , Lin Chi-Yun , Zhang Bo , Sil Debangsu , Schaperdoth Irene , Saryazdi Setareh , Grossman Robert , Krebs Carsten , Bollinger Jr. J. Martin
Published: March 2024

N-Acetylnorloline synthase (LolO) is one of several iron(II)- and 2-oxoglutarate-dependent (Fe/2OG) oxygenases that catalyze sequential reactions of different types in biosynthetic pathways that provide valuable natural products. LolO hydroxylates C2 of 1-exo-acetamidopyrrolizidine before coupling the C2-bonded oxygen to C7 to form the tricyclic (nor)loline core. Each reaction requires abstraction of hydrogen (H•) from carbon by an oxoiron(IV) (ferryl) intermediate, but different sites are targeted, and the carbon radicals have different fates. There have been prior indications that the disposition of the substrate and the intermediate in the active site controls the site of H• abstraction and can impact the fate of the radical in related enzymes. These indications led us to determine whether active-site reconfiguration in the second LolO-catalyzed reaction might contribute to the observed change in the outcome. Whereas the single ferryl complex in the C2 hydroxylation reaction was previously shown to have typical Mössbauer parameters, the second of two ferryl complexes to accumulate during the oxacyclization step has an isomer shift greater than that of any such complex characterized to date in an Fe/2OG enzyme. Moreover, it abstracts H• from C7 ~20 times faster than does the first ferryl complex in its previously reported off-pathway hydroxylation of C7. The detectable hydroxylation of C7 in competition with cyclization by the second ferryl complex is not enhanced in 2H2O solvent, suggesting that the C2 hydroxyl is deprotonated prior to C7–H cleavage. These observations are consistent with coordination of the C2 oxygen to the second ferryl complex, which may reorient its oxo ligand, the substrate, or both to positions more favorable for C7–H cleavage and cyclization.
Cross-Coupling of CO and an Isocyanide Mediated by a Tetrameric Magnesium Hydride Cluster
Authors: Yang Wenbang , White Andrew , Crimmin Mark
Published: March 2024

Sequential addition of CNXyl (Xyl = 2,6-dimethylphenyl) and CO to a tetrametallic magnesium hydride cluster results in stepwise reduction and cross-coupling of these substrates. Cross-coupling results in the formation of an ethene amidolate ligand [OC1(H1)=C2(H2)NAr]2– a previously unknown entity which contains a 1,2-difunctionalised carbon chain reminiscent of those found in aminoalcohols and aminoacids. To the best of our knowledge, this is the first example of such reactivity with metal hydride precursors. DFT calculations support a mechanism that parallels that established for coupling of CO to form ethenediolate ligands, with the key carbon–carbon bond step occurring by nucleophilic attack of a putative azamethylene intermediate on CO. The cluster plays a key role in templating the synthesis, providing kinetic control over each of the steps. The ethene amidolate ligand can be transferred to other metals (Al) and semi-metals (B) through onwards metathesis reactions.
Study on the Diagnostic Effect of Serum Tumor Marker Detection on Benign and Malignant Pelvic Tumors
Authors: Yu Juan
Published: March 2024

Objective: To analyze the diagnostic effect of serum tumor marker detection for benign and malignant pelvic tumors. Methods: A total of 90 subjects, including healthy individuals and patients with benign and malignant pelvic tumors, were selected for research from April 2021 to July 2022. Two milliliters of venous blood were drawn on an empty stomach in the early morning. The serum was separated and processed within 2 hours, and then microparticle chemiluminescence was used to detect various serum tumor markers, including carcinoembryonic antigen (CEA), alpha-fetoprotein (AFP), carbohydrate antigen 125 (CA- 125), and carbohydrate antigen 19-9 (CA19-9). Results: Through testing of the observation and control groups, it was found that patients with pelvic tumors had significantly higher CA-125 and CA19-9 (P < 0.05). Additionally, CA-125 and CA19-9 in patients with malignant tumors were significantly higher than those in benign patients (P < 0.05). The correlation between CEA and AFP and pelvic tumor is low, while CA-125 and CA19-93 are positively correlated with the severity of the disease. Conclusion: Multiple serum tumor marker detection demonstrated a higher value for diagnosing benign and malignant pelvic tumors and can improve the sensitivity and specificity of single marker detection. Analysis of CA-125 and CA19-9 levels accurately distinguishes between benign and malignant pelvic tumors, as well as provides data support for clinical treatment.
Analysis of the Effectiveness of Modified Non-Traumatic Filling Technology in the Treatment of Pediatric Dental Caries
Authors: Liu Yi
Published: March 2024

Objective: To analyze the effectiveness of modified non-traumatic filling technology in the treatment of pediatric dental caries. Methods: Ninety-seven children with dental caries who were treated in our hospital (Panyu Maternal and Child Care Service Center of Guangzhou) from January 2022 to December 2023 were selected and randomly divided into two groups, with 48 cases in the experimental group and 49 in the control group. The experimental group was treated with modified non-traumatic filling techniques, while the control group was treated with conventional filling techniques. Observation indicators such as the total effectiveness of the treatment, incidence of adverse events, treatment compliance, and pain scores were analyzed after the intervention. Result: After intervention, the total effectiveness of the treatment in the experimental group was higher than that in the control group (P < 0.05). The incidence of adverse events in the experimental group was lower than that of the control group (P < 0.05). The treatment compliance of patients in the experimental group was higher than that in the control group (P < 0.05). The pain score of the experimental group was lower than that of the control group (P < 0.05). Conclusion: The application of modified non-traumatic filling technology in the treatment of pediatric dental caries showed good therapeutic outcomes. After the intervention, the child’s symptoms were significantly alleviated, the incidence of adverse events such as filling material falling off was reduced, their compliance was improved, and the pain was relieved. This procedure is worth to be promoted for clinical application.
ANALISIS DAN DESAIN SISTEM APLIKASI PENJADWALAN KULIAH PENGGANTI (RESCHEDULE-IN) BAGI MAHASISWA DAN DOSEN DI UNIVERSITAS
Authors: Amaliyah Putri , Aulia Putri Faza , Akbar Muhammad Farhan , Maulidana Royhan Aditya , Safitri Anita
Published: March 2024

The process of scheduling replacement classes is a crucial activity in a university environment. This task is performed when events occur that result in the cancellation of scheduled classes, such as a teacher's unavailability, emergency situations, and others. The manual approach to scheduling replacement classes often takes a long time, lacks efficiency, and is prone to errors. Therefore, an efficient system for scheduling replacement classes is needed. The Object-Oriented Analysis and Design (OOAD) methodology is used for the analysis, which includes various diagrams such as use case diagrams, use case scenarios, sequence diagrams, and activity diagrams.
PENGUKURAN KINERJA TENAGA KESEHATAN RUMAH SAKIT BERDASARKAN METODE MALCOLM BALDRIGE NATIONAL QUALITY AWARD
Authors: Labibah Zulfa , Haksama Setya
Published: March 2024

Performance is the most important aspect of hospital operations. Bed Occupancy Rate (BOR) shows the productivity of using inpatient beds and can also show the performance of the hospital staff. The BOR rate in the inpatient unit of RS X in 2020-2022 was below the ideal rate of 60-85%. This study aims to measure the performance of the inpatient unit of RS X based on the seven Malcolm Baldrige criteria. This type of research is descriptive research with a cross-sectional approach. The population in this research is all nurses of the inpatient unit of X Hospital which amounted to 201 people. The sample was taken using simple random sampling method and calculated the proportion of each room with a sample size of 138 people. Data were collected using a questionnaire consisting of 49 statements. The results of the study obtained a percentage of achievement based on the Malcolm Baldrige score on leadership criteria of 85.25%, strategic planning criteria of 84.0%, customer focus criteria of 86.94%, PAMP criteria of 82.89%, human resource focus criteria of 84.94%, operational focus criteria of 85.88%, and results criteria of 83.58%. Overall performance achievements based on the seven Malcolm Baldrige criteria are in the excellent level 2 category, except for the measurement, analysis, and knowledge management criteria which are in the excellent level 1 category. So, efforts still need to be made to improve performance in the inpatient unit, especially in the measurement, analysis, and knowledge management categories.
Analisis Penggunaan Media Spelling Puzzle untuk Meningkatkan Kemampuan Membaca Permulaan Siswa Disleksia di Sekolah Dasar Penyelenggara Pendidikan Inklusi
Authors: Agustin Ina , Widiyanti Ifa Seftia Rakhma
Published: March 2024

Children with special needs require educational services in the form of a different learning process from children in general. One kind of child with special needs is a dyslexic child. In general, dyslexic children experience several learning difficulties, one of which is difficulty reading and writing. This study aims to analyze the use of spelling puzzle media in improving the reading ability of dyslexic children. The subjects in this study were dyslexic grade III students at SDN Tambakboyo II who collected four students. The method used in this research is descriptive qualitative. Data was collected through interviews, reading tests and observations. Data is presented in the form of diagrams and then analyzed descriptively. The main problem in this study is whether the spelling puzzle media can help dyslexic children improve reading skills. The results showed that the use of spelling puzzle media can improve reading skills at the beginning reading level. Increased reading ability as a reaction to the increase in memory and motivation of dyslexic children through spelling puzzle pieces. Other findings in this study increased learning activities, motivation and interest in reading dyslexia.
Profiles of Learning Models and Media While Online Study During the Covid-19 Pandemic: A Literature Review
Authors: Rizki Iqbal Ainur , Saphira Hanandita Veda , Citra Nina Fajriyah
Published: March 2024

The Covid-19 pandemic has had a major impact on education in Indonesia. Therefore, teachers need to build a learning system using media and learning models following current pandemic conditions. In this regard, the study is focused on analyzing effective learning models and media to provide their advantages and disadvantages when used during online learning so that teachers can choose a learning system that suits students' needs and conditions. This research uses literature study methods with qualitative descriptive analysis. There are 12 journals that have been successfully obtained and reviewed from the title, research results, and conclusions. The findings showed that suitable online learning models are student-centered learning models such as PjBL, PBL, DL, ORNE, Cooperative TGT, and guided inquiry. In addition, the use of ICT-based interactive media can improve learning outcomes, motivation and creativity of learners, also support the implementation of online learning well.
Pengembangan Papan Make and Match sebagai Media Penguasaan Multi-Literasi Peserta Didik TK
Authors: Sari Arviani , Ngatmini Ngatmini , Siswanto Joko
Published: March 2024

Learning media is one of the important components used in learning activities. Good learning media can help students achieve competence. Based on observations, it is known that the multiliteracy abilities of group B students of TK Masyitoh Karangasem Batang such as: the ability to read, write and count are not maximized, teachers in providing learning still use conventional methods, as a result many students experience boredom and boredom. boredom is a natural thing especially learning that tends to be monotonous. The feeling of boredom and saturation that comes is not good and will greatly affect the learning process of students. If you are bored then someone will be lazy to do it. If the feeling of laziness in learning is left longer, the result is that the achievement and academic value of students will certainly decrease.This study aims to describe the validity of the make and match board which was developed as a medium for mastering multiliteracy for kindergarten students. describe the practicality of the make and match board which was developed as a medium for mastering multiliteracy for kindergarten students.This study uses a 4D development research approach adapted from the Thiagarajan and Semmel development model with 3 steps: 1) Define (defining); (2) Design (design); (3) Develop (development). Data collection techniques were carried out by tests, observations, questionnaires, interviews and documentation. The data analysis technique uses product data analysis, initial data analysis, t test and gain test.The results showed that the make and match board was feasible to use with the results of the validity test using aiken V in the medium and high categories and the reliability test in the strong category. make and match boards are feasible to be effectively used in learning, it is known that based on learning outcomes there is an average difference through the t test of -10.578 and an average increase (gain) of 0.535 which based on the interpretation of the gain index is classified as moderate.The conclusion of this research is that the make and match board is feasible and effective to use in learning, especially in mastering multi-literacy materials to explore new knowledge from the make and match board media. Teachers are expected to be able to develop make and match boards that are similar to different materials, and the school is expected to facilitate.