bluuebunny/crossref_metadata_2025 huggingface dataset:
Total hip arthroplasty versus hemiarthroplasty for displaced femoral neck fracture: a protocol for an overview of systematic reviews
Authors: Falotico Guilherme Guadagnini , Moraes Vinicius Ynoe , Matsunaga Fabio Teruo , Tamaoki Marcel Jun Sugawara , Faloppa Flavio , Belloti João Carlos
Published: November 2021

Introduction

Hip arthroplasties for the treatment of displaced femoral neck fractures in adults can be total replacement or hemiarthroplasty. Despite the high prevalence of these fractures and large number of studies on the topic, the best choice of arthroplasty to be used remains unclear. The present study aims to overview the results of systematic reviews of randomised controlled trials (RCTs) comparing outcomes between total hip replacement and hemiarthroplasty for displaced femoral neck fractures in adults.

Methods and analysis

Four electronic databases (Pubmed, Embase, Cochrane Library and Web of Science) and reference lists from previous reviews will be searched without language limitation. Eligible studies will be systematic reviews of RCT that compare total hip replacement and hemiarthroplasty for treatment of displaced femoral neck fractures in adults. Two reviewers will independently perform study selection, data extraction and quality assessment. Disagreements between reviewers will be resolved by a third reviewer. Comparisons of dichotomous data will report as the OR and 95% CI, and comparisons of functional and health-related quality of life outcomes are reported as the mean difference and 95% CI and as the risk difference, defined as the difference in the proportion achieving the minimum clinically important difference and 95% CI. As this overview will contribute to orthopaedic surgeons and health managers in better decision-making for the treatment of these fractures. The authors plan to complete the searches and analyses by 30 November 2021.

Ethics and dissemination

Ethical approval was obtained at Federal University of Sao Paulo. Findings will be disseminated through peer-reviewed publication.

PROSPERO registration number

CRD42021237885.
Assessing the relationship between adverse pregnancy outcomes and area-level deprivation in Wales 2014–2019: a national population-based cross-sectional study
Authors: Brown Heather , Jesurasa Amrita , Bambra Clare , Rankin Judith , McNaughton Amy , Heslehurst Nicola
Published: November 2021

Objectives

The aim of this study was to assess the relationship between deciles of area-level deprivation and seven adverse pregnancy outcomes in Wales.

Design

Cross-sectional analysis.

Setting

64 699 live births in Wales from 31 March 2014 to 16 September 2019.

Primary outcome variable

We examined each of the following seven adverse pregnancy outcomes: (1) small for gestational age (SGA); (2) large for gestational age; (3) preterm birth; (4) third-degree or fourth-degree perineal tear; (5) major postpartum haemorrhage (MPPH); (6) a lower Apgar score at 5 min and (7) emergency caesarean section.

Results

There was no significant association between increasing aggregate measures of area-level deprivation and the adverse pregnancy outcomes we studied. Women living in an area with greater access to services are more likely to have a baby that is SGA (1.27, 95% CI 1.11 to 1.49), have a greater likelihood of a perineal tear (1.74, 95% CI 1.15 to 2.61), are significantly less likely to have MPPH (0.79, 95% CI 0.64 to 0.96), have a baby with an Apgar score of 0.26 higher (95% CI 0.22 to 0.29) and are significantly less likely to have an emergency caesarean section (0.81, 95% CI 0.73 to 0.88). Women living in areas with higher employment (0.26, 95% CI 0.19 to 0.36) and better health (0.26, 95% CI 0.19 to 0.35) were less likely to experience perineal tear.

Conclusions

There was no clear social-spatial gradient in area-level deprivation and adverse pregnancy outcomes. We found a stronger association for individual-level behavioural risk factors than area-level factors. These findings support the benefits that accessible and holistic person-centred care may bring through addressing individual behavioural risk factors. There is a need for improved data completeness and further individual-level data on risk factors such as employment and income to better understand the role which may be played by population-level policies and their pathways to affecting outcomes.
Temporal trends of carbon monoxide poisoning mortality at the global, regional and national levels: a cross-sectional study from the Global Burden of Disease study, 1990 and 2017
Authors: Long Jianhai , Sun Yawei , Zhao Junxiu , Liu Jie , Peng Xiaobo
Published: November 2021

Objectives

Carbon monoxide (CO) poisoning is one of the most frequent causes of fatal poisoning worldwide. Few studies have explored the mortality trends of CO poisoning grouped by age and gender, at the regional, national and global levels. We therefore aimed to determine the pattern of CO poisoning mortality, as well as temporal trends at all levels.

Design

A cross-sectional survey design was used in this study.

Setting

CO poisoning data collected from the Global Burden of Diseases (GBDs), from 1990 to 2017, was arranged by sex, age, region and country. In addition, we used human development index data at the national level from the World Bank.

Participants

We collected over 100 000 information on CO poisoning mortality between 1990 and 2017, derived from the GBD study in 2017.

Main outcomes and measures

We have calculated the estimated annual percentage changes in CO poisoning age-standardised mortality rate (ASR), by sex and age at different regions and countries to quantify the temporal trends in CO poisoning ASR.

Results

Globally, death cases of CO poisoning decreased 7.2% from 38 210 in 1990 to 35 480 in 2017. The overall ASR decreased by an average of 1.83% (95% CI 2.10% to 1.56%) per year in this period. This decreasing pattern was heterogeneous across ages, regions and countries. The most pronounced decreases were generally observed in countries with a high sociodemographic index, including Estonia, South Korea and Puerto Rico.

Conclusions

Current prevention strategies should be reoriented, and much more targeted and specific strategies should be established in some countries to forestall CO poisoning.
Predictors of response to TNF inhibitors in rheumatoid arthritis: an individual patient data pooled analysis of randomised controlled trials
Authors: Law-Wan Johan , Sparfel Marc-Antoine , Derolez Sophie , Azzopardi Nicolas , Goupille Philippe , Detert Jacqueline , Mulleman Denis , Bejan-Angoulvant Theodora
Published: November 2021

Objective

To identify patient characteristics associated with responsiveness to tumour necrosis factor inhibitors (TNFi) in rheumatoid arthritis (RA).

Materials and methods

Individual patient data from 29 randomised controlled trials (RCTs) evaluating the efficacy of a TNFi versus placebo or conventional therapy were obtained. Response to treatment was assessed in subgroups according to the following baseline characteristics: smoking status, physical activity, sex, age, body mass index, autoantibody profile, disease duration, high initial disease activity defined by Disease Activity Score on 28 joints (DAS28)(C reactive protein (CRP)) >5.1. The primary outcome was the between-treatment group difference in DAS28(CRP) change from baseline to 6 months. The secondary endpoints were the between-treatment group difference in final DAS28(CRP) measured until 6 months and EULAR response criteria until 6 months. Data from each RCT were then pooled by the Mantel-Haenszel method using a random effects model. A linear metaregression was also carried out on two data-sharing platforms separately to support the results.

Results

Individual data of 11 617 patients from 29 RCTs were analysed. Until 6 months, a significantly higher EULAR non-response rate was observed in obese patients (OR 0.52 vs 0.36 for non-obese, p=0.01). A multivariable regression model performed on 7457 patients indicated that patients treated by TNFi had a final DAS28(CRP) decreased by 0.02 for each year of disease duration (p<0.001), and a 0.21 decreased for patients with a baseline DAS28(CRP) >5.1 (p<0.001).

Conclusions

In RA, patients who are more responsive to TNFi are those who are non-obese, have a long disease duration and have a high initial disease activity.
BotSpot++: A Hierarchical Deep Ensemble Model for Bots Install Fraud Detection in Mobile Advertising
Authors: Zhu Yadong , Wang Xiliang , Li Qing , Yao Tianjun , Liang Shangsong
Published: November 2021

Mobile advertising has undoubtedly become one of the fastest-growing industries in the world. The influx of capital attracts increasing fraudsters to defraud money from advertisers. Fraudsters can leverage many techniques, where bots install fraud is the most difficult to detect due to its ability to emulate normal users by implementing sophisticated behavioral patterns to evade from detection rules defined by human experts. Therefore, we proposed BotSpot

1

for bots install fraud detection previously. However, there are some drawbacks in BotSpot, such as the sparsity of the devices’ neighbors, weak interactive information of leaf nodes, and noisy labels. In this work, we propose BotSpot++ to improve these drawbacks: (1) for the sparsity of the devices’ neighbors, we propose to construct a super device node to enrich the graph structure and information flow utilizing domain knowledge and a clustering algorithm; (2) for the weak interactive information, we propose to incorporate a self-attention mechanism to enhance the interaction of various leaf nodes; and (3) for the noisy labels, we apply a label smoothing mechanism to alleviate it. Comprehensive experimental results show that BotSpot++ yields the best performance compared with six state-of-the-art baselines. Furthermore, we deploy our model to the advertising platform of Mobvista,

2

a leading global mobile advertising company. The online experiments also demonstrate the effectiveness of our proposed method.
Combining Network Pharmacology with Molecular Docking for Mechanistic Research on Thyroid Dysfunction Caused by Polybrominated Diphenyl Ethers and Their Metabolites
Authors: He Qiaoyu , Chen Xiaopeng , Liu Jing , Li Chunxia , Xing Hong , Shi Yumeng , Tang Qian
Published: November 2021

Network pharmacology was used to illuminate the targets and pathways of polybrominated diphenyl ethers (PBDEs) causing thyroid dysfunction. A protein‐protein interaction (PPI) network was constructed. Molecular docking was applied to analyze PBDEs and key targets according to the network pharmacology results. A total of 247 targets were found to be related to 16 PBDEs. Ten key targets with direct action were identified, including the top five PIK3R1, MAPK1, SRC, RXRA, and TP53. Gene Ontology (GO) functional enrichment analysis identified 75 biological items. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis identified 62 pathways mainly related to the regulation of the thyroid hormone signaling pathway, MAPK signaling pathway, PI3K‐Akt signaling, pathways in cancer, proteoglycans in cancer, progesterone‐mediated oocyte maturation, and others. The molecular docking results showed that BDE‐99, BDE‐153, 5‐OH‐BDE47, 5 ′‐OH‐BDE99, 5‐BDE47 sulfate, and 5 ′‐BDE99 sulfate have a good binding effect with the kernel targets. PBDEs could interfere with the thyroid hormone endocrine through multiple targets and biological pathways, and metabolites demonstrated stronger effects than the prototypes. This research provides a basis for further research on the toxicological effects and molecular mechanisms of PBDEs and their metabolites. Furthermore, the application of network pharmacology to the study of the toxicity mechanisms of environmental pollutants provides a new methodology for environmental toxicology.
Effects of Combined Cognitive and Exercise Interventions on Poststroke Cognitive Function: A Systematic Review and Meta‐Analysis
Authors: Sun Ruifeng , Li Xiaoling , Zhu Ziman , Li Tiancong , Li Wenshan , Huang Peiling , Gong Weijun
Published: November 2021

Objective. We investigated combined cognitive and exercise interventions in the literature and summarized their effectiveness in improving poststroke cognitive impairment (PSCI). Data Sources. Electronic databases and trial registries were searched from their inception until July 2020. Study Selection. Trials were collected with the following study inclusion criteria: (1) patients over 18 years of age who were diagnosed with PSCI; (2) combined cognitive‐exercise interventions, regardless of the order of the two types of interventions or whether they were administered simultaneously; (3) any control group studied at the same time that was deemed acceptable, including no intervention/routine care, delayed intervention, sham intervention, and passive training; (4) the use of any validated cognitive neuropsychological test to evaluate cognitive function; and (5) clinically administered random trials with controls. Data Extraction. Five randomized controlled trials met the inclusion criteria. Two reviewers independently assessed the eligibility of the full texts and methodological quality of the included studies using the Cochrane risk of bias tool. Inconsistent results were resolved by additional discussion or decided by a third examiner, if necessary. Data Analysis. Meta‐analysis demonstrated that the combined interventions had a significant effect on executive function and working memory [Stroop test (time), standardized mean difference (SMD) = 0.42, 95% confidence interval (CI): 0.80–0.04, p = 0.02; Trail Making Test, SMD = 0.49, 95% CI: 0.82–0.16, p = 0.004; Forward Digit Span Test, SMD = 0.91, 95% CI: 0.54–1.29, p ≤ 0.001]. While it was impossible to conduct a meta‐analysis of global cognitive function and other cognitive domains, individual experiments demonstrated that the combined interventions played a significant role in global cognition, reasoning ability, logical thinking, and visual‐spatial memory function. Conclusions. Our analyses demonstrated that the combined interventions had a significant effect on the improvement of PSCI, particularly in terms of executive function. However, the moderate risk of bias in the included trials and the small number of relevant studies indicated a need for more uniform diagnostic and evaluation criteria, and larger trials would provide stronger evidence to better understand the effectiveness of the combined interventions. This trial is registered with trial registration number INPLASY202160090.
Symptomatic Medial Bone Excrescence in the Distal Phalanx of the Hallux after the First Metatarsophalangeal Joint Arthrodesis: A Case Report and Radiographic Reviews
Authors: Maenohara Yuji , Takeda Ryutaro , Chang Song Ho , Omata Yasunori , Tanaka Sakae , Matsumoto Takumi
Published: November 2021

Medial bone excrescence at the base of the distal phalanx of the hallux is a common manifestation which is rarely painful. In this case report, we described the first case of the excrescence becoming symptomatic one year after a metatarsophalangeal (MTP) joint arthrodesis of the great toe in a 74-year-old female. The medial bony excrescence which was obscure preoperatively became obvious postoperatively in the anteroposterior foot radiographs. The patient was successfully treated by an excision of the excrescence. In order to clarify the pathology of the excrescence, we reviewed the radiographs with respect to the excrescence before and after hallux surgeries including 97 metatarsal osteotomies and 33 MTP joint arthrodesis. The width of the excrescence measured in the anteroposterior foot radiographs displayed substantial increment one month after the hallux surgeries (osteotomy group:

0.9
±
0.7

vs.

1.5
±
0.7
 
mm

,

p
<
0.01

; arthrodesis group:

1.3
±
0.8

vs.

1.8
±
1.0
 
mm

,

p
<
0.01

). However, there was no significant difference in the width of the excrescence between one month after surgery and at the most recent follow-up of around 20 months in average after the surgery (osteotomy group:

1.5
±
0.7

vs.

1.4
±
0.7
 
mm

,

p
=
0.62

; arthrodesis group:

1.8
±
1.0

vs.

1.8
±
0.7
 
mm

,

p
=
0.37

). The present case and our radiographic review suggested that the postoperative medial bony excrescence was not the result of change of position of the preexisting excrescence. The correction of pronation deformity through hallux surgeries could emphasize the medial bony excrescence and cause symptomatic irritation upon shoe contact.
Tuning of Photoluminescence and Antibacterial Properties of ZnO Nanoparticles through Sr Doping for Biomedical Applications
Authors: Karthick R. , Sakthivel P. , Selvaraju C. , Paulraj Mosae Selvakumar
Published: November 2021

Sr-doped ZnO nanoparticles have been synthesized using a soft chemical method. The doping ratio of Sr is varied in the range of 0 at.%, 3 at.%, and 5 at.% to 7 at.%. X-ray diffractograms revealed that the samples had hexagonal (wurtzite) structure without a trace of any mixed phase. The average crystallite size of the nanoparticles (NPs) ranged from 39 to 46 nm. The average crystallite size was increased for the initial doping (3 at.%) of Sr ions, and further increase in the doping ratio reduced the particle size due to some distortion produced in the lattice. The surface morphology of the samples and structure of the NPs were investigated using FESEM (Field Emission Scanning Electron Microscopy) and TEM (Transmission Electron Microscopy) pictures, respectively. EDX (energy-dispersive X-ray) spectroscopy confirmed the presence of strontium (Sr) in the host lattice. Photoluminescence and X-ray diffraction confirmed that the dopant ions replace some of the lattice zinc ions and that Sr2+ and Sr3+ ions coexist in the ZnO lattice. The Sr-doped ZnO exhibited violet and blue luminescence spectra at 408 nm and 492 nm, respectively. ZnO : Sr nanoparticles showed increased antibacterial activity against one gram-positive as well as one gram-negative bacteria.
Real‐Time Capture of Snowboarder’s Skiing Motion Using a 3D Vision Sensor
Authors: Li Zhipeng , Wang Jun , Zhang Tao , Balne Dave , Li Bing , Yang Ruizhu , Song Wenli , Zhang Xingfu
Published: November 2021

Due to the influence of environmental interference and too fast speed, there are some problems in ski motion capture, such as inaccurate motion capture, motion delay, and motion loss, resulting in the inconsistency between the actual motion of later athletes and the motion of virtual characters. To solve the above problems, a real‐time skiing motion capture method of snowboarders based on a 3D vision sensor is proposed. This method combines the Time of Fight (TOF) camera and high‐speed vision sensor to form a motion acquisition system. The collected motion images are fused to form a complete motion image, and the pose is solved. The pose data is bound with the constructed virtual character model to drive the virtual model to synchronously complete the snowboarding motion and realize the real‐time capture of skiing motion. The results show that the motion accuracy of the system is as high as 98.6%, which improves the capture effect, and the motion matching proportion is better and more practical. It is also excellent in the investigation of motion delay and motion loss.
Endoscopy Capsule Retention in a Young Female with Small Bowel Strictures Secondary to Non-Steroidal Anti-Inflammatory Drugs
Authors: Tayyub Muhammad Umair , Egan Laurence , Goulding Carol
Published: November 2021

Non-steroidal anti-inflammatory drugs (NSAIDs) can cause small bowel damage, which could present in different ways, including abdominal pain and occult gastrointestinal bleeding. NSAID use can also result in small bowel strictures, which can be challenging to diagnose and manage. Here, we describe a case of a 49-year-old female who presented with chronic anaemia and intermittent abdominal pain, with a history of NSAID use. She underwent capsule endoscopy as part of the workup for anaemia and subsequently had capsule retention due to a small bowel stricture.
Feasibility of Imaging-Guided Adrenalectomy in Young Patients With Primary Aldosteronism
Authors: Rossi Gian Paolo , Crimì Filippo , Rossitto Giacomo , Amar Laurence , Azizi Michel , Riester Anna , Reincke Martin , Degenhart Christoph , Widimsky Jiri , Naruse Mitsuhide , Deinum Jaap , Kool Leo Schultze , Kocjan Tomaz , Negro Aurelio , Rossi Ermanno , Kline Gregory , Tanabe Akiyo , Satoh Fumitoshi , Rump Lars Christian , Vonend Oliver , Willenberg Holger S. , Fuller Peter J. , Yang Jun , Chee Nicholas Yong Nian , Magill Steven B. , Shafigullina Zulfiya , Quinkler Marcus , Oliveras Anna , Wu Vin Cent , Kratka Zuzana , Barbiero Giulio , Battistel Michele , Seccia Teresa Maria
Published: November 2021

Many of the patients with primary aldosteronism (PA) are denied curative adrenalectomy because of limited availability or failure of adrenal vein sampling. It has been suggested that adrenal vein sampling can be omitted in young patients with a unilateral adrenal nodule, who show a florid biochemical PA phenotype. As this suggestion was based on a very low quality of evidence, we tested the applicability and accuracy of imaging, performed by computed tomography and/or magnetic resonance, for identification of unilateral PA, as determined by biochemical and/or clinical cure after unilateral adrenalectomy. Among 1625 patients with PA submitted to adrenal vein sampling in a multicenter multiethnic international study, 473 were ≤45 years of age; 231 of them had exhaustive imaging and follow-up data. Fifty-three percentage had a unilateral adrenal nodule, 43% had no nodules, and 4% bilateral nodules. Fifty-six percentage (n=131) received adrenalectomy and 128 were unambiguously diagnosed as unilateral PA. A unilateral adrenal nodule on imaging and hypokalemia were the strongest predictors of unilateral PA at regression analysis. Accordingly, imaging allowed correct identification of the responsible adrenal in 95% of the adrenalectomized patients with a unilateral nodule. The rate raised to 100% in the patients with hypokalemia, who comprised 29% of the total, but fell to 88% in those without hypokalemia. Therefore, a unilateral nodule and hypokalemia could be used to identify unilateral PA in patients ≤45 years of age if adrenal vein sampling is not easily available. However, adrenal vein sampling remains indispensable in 71% of the young patients, who showed no nodules/bilateral nodules at imaging and/or no hypokalemia.

Registration:

URL:
https://www.clinicaltrials.gov
; Unique identifier: NCT01234220.
Social Mobility and Spatialised Slowness
Authors: Ménard Anaïs
Published: November 2021

This article analyses the individual aspirations of Sierra Leoneans living in France in relation to normative expectations related to mobility. It argues that aspirations and expectations are expressions of spatialized forms of social becoming situated within broader norms concerning socially-valued forms of mobility. Aspirations to social mobility link up distinct places in a fragmented transnational field, transform them as value-laden spaces, and inform migrants’ assessment of their own trajectory within them. Individual aspirations are formulated with regard to spaces migrants have left, spaces they live in, and spaces they would like to reach. Sierra Leoneans living in France have reached a ‘destination country’ and yet, do not experience their situation as the ideal migratory path. Their achievements are measured with regard to expectations of social mobility as imagined in English-speaking spaces, thereby reinforcing the narrative of mobility and the persistence of local idioms of ‘success’ based on historical transnational connections.
‘A Peaceful History’? West Indians, the Inner City, and Local Responses to Migration in Post-War Bristol
Authors: Hackett Sarah
Published: November 2021

Using the 1980 St. Paul’s riot as a point of departure, this article retrospectively explores migration policymaking in Bristol during the 1950s and 1960s. It charts some of the deliberations, policies and practices of three local actors who played key roles in the city’s debates and developments on migration and integration: the police, charitable, community, religious and voluntary groups and organisations, and the municipality. In doing so, it exposes a complex urban policy arena comprised of varied, multifaceted and ever-changing responses to Commonwealth immigrants, and West Indians in particular. Overall, the article argues that Bristol’s migration policies and practices of the 1950s and 1960s are crucial in light of subsequent increasing inner-city tensions and the 1980 uprising, but also because they broaden our understanding of the pivotal role that cities played in the governance of migration and diversity already during the post-war decades.
The Effectiveness of Single Injection of Platelet-Rich Plasma for Knee Osteoarthritis Combined with Meniscus Injury: A Randomized Trial
Authors: Jiao Rui , Zhang Ming-Sheng , Li Xin-Ping , Li Shu-Qian , Huang Wen-Xia
Published: November 2021

Objectives : To explore the effectiveness of single injection of platelet-rich plasma with rehabilitation therapy for knee osteoarthritis combined with meniscus injury. Methods : Forty patients who met the inclusion criteria were randomly assigned to a rehabilitation group
(REH group, 20 cases) receiving rehabilitation training, and a platelet-rich plasma group (PRP group, 20 cases) receiving an ultrasound-guided single injection of PRP in combination with rehabilitation training. Rehabilitation training in the two groups lasted for 2 weeks, and the patients
were evaluated using the short-form McGill pain questionnaire (SF-MPQ), Western Ontario McMaster Universities index (WOMAC score), and infrared thermography (knee-joint mean temperature) before treatment, at 1 week, 1 month and 6 months after treatment. Results : Two patients were lost
to follow-up in both the PRP group and the REH group. Significant reductions in pain scores, WOMAC scores and knee temperature were observed at 1 week and 1 month after treatment in both groups (p < 0.05). Significant lower SF-MPQ scores were observed in the PRP group than in the
REH group at 6 months followup (p < 0.01). Similarly, the mean knee temperature was significantly lower in the PRP group than in the REH group at 6 months follow-up (p < 0.01). No severe complications occurred in either group. Conclusions: Compared to rehabilitation
therapy alone, single injection of platelet-rich plasma in combination with rehabilitation therapy has beneficial effect on pain, knee function and mean knee temperature in patients with KOA combined with meniscus injury. Single injection of platelet-rich plasma combined with rehabilitation
therapy has a good short-term effectiveness.
Bone Mesenchymal Stem Cells (BMSCs) Transplantation Can Repair Rat Femoral Head Necrosis and Inhibit the Expression of Omgp
Authors: Wei Haiyan , Cui Yubao , Liu Zhengjie
Published: November 2021

To study the therapeutic effect of BMSCs on femoral head necrosis and whether it can inhibit the growth of OMgP. 15 healthy rats were divided into ZZ group (normal group), GT group (femoral head necrosis) and MM group (BMSCs transplantation). At 1 h, 3 h, 1 d, and 3 d, the expression
of OMgP in GT group were higher than ZZ group (P <0.05) and MM group, indicating that BMSCs transplantation can decreased OMgP expression. At 1 d, 7 d, and 14 d, BBB scores of the GT group were lower than ZZ group (P < 0.05) and MM group (P < 0.05), indicating
that BMSCs transplantation can improve spinal cord injury behavior. The cells in ZZ group were well stained and morphologically intact, the femoral head was not damaged, and the articular surface was smooth, GT group had cartilage necrosis with disordered inferior epiphysis, and the femoral
head of the MM group had less damage and increased osteoblasts. The blood vessel counts in necrotic area in GT group were higher than ZZ group and MM group with decreased new bone area in repair area compared to ZZ and MM group (P <0.05), indicating that the area of femoral head
necrosis after BMSCs transplantation was improved. The levels of ALP and BGP in GT group were lower than ZZ group (P <0.05) and MM group (P <0.05). Bone marrow mesenchymal stem cell transplantation can effectively repair new bone area, up-regulate ALP and BGP, and have
a positive effect on femoral head necrosis, possibly by inhibiting OMGP activity.
“New patriotism” in post-war Sri Lanka and the revival of the Walauva as a site of power in contemporary Sri Lankan English fiction
Authors: Perera Vihanga
Published: November 2021

An emerging body of fiction by contemporary English novelists in Sri Lanka during the immediate post-civil war decade (2010–2020) indicates a renewed interest in the feudal grand house (the walauva) as a site of power. Often described in romantic terms and presented from positions of entitlement, in its renewed form, the walauva is constructed as a benevolent patriarchal system in which class superiors and servants share cordial and meaningful relationships. With primary reference to Nayomi Munaweera’s “What Lies Between Us”, Madhubhashini Ratnayake’s “There is Something I Have to Tell You” and Charulatha Thewarathanthri’s “Stories”, I place this emergent romanticized impression of the feudal grand house within the centralist power agenda of majoritarian populism prevalent in post-civil war Sri Lanka: a mass consciousness engineered by Sinhalese nationalist political fronts postwar, which historian Nira Wickramasinghe terms Sri Lanka’s ‘new patriotism’. While appreciating the contemporary writer’s imagination as being shaped by demands of ‘new patriotism’ the article identifies a deviation of her reading from the representations of the walauva as a site of power by Sri Lanka’s English literary canon from the 1950s to the mid-1990s.
Influence of out-of-plane fiber waviness and different environmental conditionings on mechanical and morphological characteristics of fiber glass/epoxy laminates
Authors: Barros André Santiago , Vieira Leonardo de Souza , Morgado Guilherme Ferreira de Melo , dos Anjos Erick Gabriel Ribeiro , Souza Gabriel Portilho Monteiro de , Souza Maria Fernanda Romeu Lino de , Wearn Yves Nicolau , Nardi Antonio Luís Braga De , Coimbra Maria Claudia Ribeiro , Moura Nayara Koba de , Leite Cristiano Idalgo , Rezende Mirabel Cerqueira
Published: November 2021

The use of structural polymeric composites constitutes an interesting option in the area of wind turbine blade manufacturing. Nevertheless, thick composite components may present out-of-plane waviness in their fibers, compromising the service life of the wind blades. In this context, the present study aims to study the influence of out-of-plane waviness in the fibers with different degrees of severity as well as to verify the effect of fiber glass/epoxy resin composites immersion in distilled water and saline solution in their tensile strength (σmax), modulus of elasticity (E), and deformation at break (єrup), analyzing the reinforcement/matrix interface changes. The results showed that the increase in severity promoted, in general, a statistically significant deterioration in σmax of the samples exposed to the same environmental conditioning. The conditioning led to a decrease in E and an increase in єrup, attributed to the deterioration of the interface and the plasticization of the polymeric matrix, respectively, as evidenced by fractographic analysis. The effect of severity on the єrup and σmax properties was only noticed in laminates exposed to environmental conditioning, due to water sorption favoring the deterioration of the matrix/reinforcement interface, intensifying the deleterious effect of out-of-plane waviness of fibers.
Paris Message: One University’s Response
Authors: Bair Richard Allan , Fox Rebecca MacMillan , Bair Beth Teagarden
Published: November 2021

This article looks at the projections on the current state of the world’s post-secondary education and a prediction of what will need to be addressed and in place by 2030, in order to prepare for a significant rise in student enrollment. UNESCO presented governments and higher education institutions with a call to action to implement policies and procedures to provide accessible, equitable, and quality education via digital technology. This paper discusses the various actions the University of Miami put in place as a global provider of education and training to all learners including transitioning to micro-credentials, cultural understanding workshops, course design for academic disciplines, and engaging adult online learners.
Blowback or overblown? Why civilians under threat support invasive foreign intervention
Authors: Knuppe Austin J
Published: November 2021

How do military tactics shape civilian support for foreign intervention? Critics contend that invasive tactics undermine popular support by alienating the civilian population. Counterexamples suggest that civilians will support invasive tactics when foreign counterinsurgents are willing and able to mitigate a proximate threat. I reconcile these divergent findings by arguing that civilian support is a function of threat perception based on three interacting heuristics: social identity, combatant targeting, and territorial control. To evaluate my theory, I enumerate a survey among Iraqi residents in Baghdad during the anti-ISIS campaign. Respondents preferred more invasive tactics when foreign counterinsurgents assisted the most effective local members of the anti-ISIS coalition. Across sectarian divides, however, respondents uniformly opposed the deployment of foreign troops. These findings suggest that in regime-controlled communities, civilians will support counterinsurgents who are invasive enough to mitigate insurgent threats, but not too invasive as to undermine local autonomy.
Methotrexate in erythema nodosum leprosum: Pitfalls to avoid
Authors: Mehta Hitaishi , Narang Tarun , Dogra Sunil , Kumar Bhushan
Published: November 2021

We read with interest the short report by Rani et al. entitled “An uncommon variant of erythema nodosum leprosum responding well to methotrexate: Report of two cases.” The article describes two cases of erythema nodosum leprosum (ENL) with ‘atypical features’ and good response to low dose methotrexate. The authors address a few concerns regarding methotrexate in ENL, emphasizing the rational usage of this agent.
Afrikaner nationalism and the light side of the colonial/modern gender system: understanding white patriarchy as colonial race technology
Authors: Coetzee Azille
Published: November 2021

There is a growing body of feminist scholarship and literature exploring the ways in which Western patriarchal technologies of gender differentiation and sexual violence structure the racial categorisation and dehumanisation that define South Africa’s history of slavery, colonialism and apartheid. In this article, I consider the gendered history of white Afrikaner nationalism in the context of these insights. Using the decolonial feminist lens of María Lugones, I interpret the historical and contemporary patriarchal subjugation of the white Afrikaner woman as a site of the production and maintenance of colonial racial categories and hierarchies. Gaining a better understanding of how gender operated as a colonial mode of organisation in the process of forging the ethno-racialised white identity of the Afrikaner in the early nineteenth century in opposition to the black indigenous majority population helps to explain how the continued patriarchal subjugation of white Afrikaner women by Afrikaner men in postcolonial/postapartheid South Africa works to reassert and maintain colonial racial categories and inequalities that continue to plague the country.
Primary Middle Ear Meningioma with Intact Tympanic Membrane: A Case Report and Literature Review
Authors: Liu Yuan-Jun , Han Lin , Cao Jie , Zheng Hong-Wei , Yu Li-Sheng
Published: November 2021

Primary ectopic meningioma of the middle ear is relatively rare in clinical practice. It is often difficult to distinguish it from chronic otitis media or otitis media with effusion due to its similar and atypical clinical symptoms. We report a case of epithelial tympanic ectopic meningioma with the main complaints of otalgia, aural fullness, and hearing loss. It was accidentally discovered during tympanotomy due to the symptoms of recurring refractory secretory otitis media. This article briefly reviews the relevant literature in recent years, summarizes the characteristics of primary ectopic tympanic meningioma with intact tympanic membrane, and emphasizes the diagnosis and treatment strategy of the middle ear mass.
Are Community Colleges an Alternative Path for Hispanic Students to Attain a Bachelor's Degree?
Authors: Melguizo Tatiana
Published: November 2021

Background/Context

This study contributes to the longstanding debate over whether community colleges democratize education or divert students from attaining a bachelor's degree.

Purpose/Objective/Research Question/Focus of Study

The objective of this study is to determine whether Hispanic students have a lower chance of earning a bachelor's degree (B.A.) if they transfer from a community college.

Population/Participants/Subjects

This study uses the High School and Beyond Sophomore sample (HS&B/So) high school senior class of 1982 and the National Education Longitudinal Study (NELS:88/2000) high school senior class of 1992 to compare the progress of two samples of “traditional” Hispanic transfer and Hispanic “rising junior” students. The final sample is composed of 220 students from the high school senior class of 1982 and 140 students from the high school senior class of 1992.

Research Design

Regression analysis is used to identify the effect of being a transfer student on B.A. attainment, after controlling for individual characteristics and institutional characteristics of the community college. Simulation analysis is used to identify the factors that affected B.A. attainment in the 1980s, which are used to predict B.A. rates a decade later.

Findings/Results

The results show that the negative impact of being a transfer student in the 1980s had disappeared within a decade. The results suggest that the relatively lower attainment rate of Hispanic transfer students is the result of individual characteristics and lack of academic preparation rather than institutional characteristics.

Conclusions/Recommendations

Although community colleges have the potential to be an alternative path toward a B.A., until transfer rates increase, Hispanics may be better off beginning their college education at a 4-year institution.
Shared Planning Time: A Novel Context for Studying Teachers’ Discourse and Beliefs About Learning and Instruction
Authors: Gill Michele Gregoire , Hoffman Bobby
Published: November 2021

Background/Context

Although teachers’ core instructional beliefs are difficult to accurately measure, they provide a framework for understanding the thinking that underlies important curricular and pedagogical decisions made in the classroom. Previous research has primarily used self-report to study teacher beliefs, but self-report is better for reporting explicit cognitions rather than implicit ones, such as beliefs.

Purpose/Objective/Research Question/Focus of Study

The purpose of our study was to investigate teacher talk during shared planning time to provide insight into the rationales behind teachers’ decision making that may be related to their underlying beliefs about subject matter, teaching, learning, and their students.

Setting

Xavier Middle School is located in a suburban area of a midsized progressive city in Florida and has a teacher-student ratio of about 1:19. It serves sixth- through eighth graders, and 28% of the student population are minority students.

Population/Participants/Subjects

A team of 4 eighth-grade mathematics teachers at a suburban middle school in the southern part of the United States agreed to participate in this study.

Research Design

A qualitative case study of eighth-grade mathematics teachers’ discourse was conducted during their weekly shared planning time during the course of one semester.

Data Collection and Analysis

A tape recorder and field notes were used to record the team's lesson planning discourse. After reviewing the written field notes, scenes of rich dialogue from the audiotapes were selected to be transcribed. Data from the transcripts were coded and assigned to relevant domains based on semantic relationships.

Findings/Results

We compiled all the domains related to teachers’ rationales or teachers’ thinking about learning and instruction and organized the data in a taxonomy supported by relevant examples from the transcripts. We found that these rationales and cognitions mapped onto six categories consisting of beliefs about pedagogical content, general pedagogy, subject matter, curricular choices, resources/textbooks, and students’ thinking. A consistent theme was found that reflected underlying beliefs in a traditional transmission model of instruction and learning.

Conclusions/Recommendations

This study supported our hypothesis that teachers’ collaborative planning time discourse provides a unique lens for understanding teachers’ beliefs. Furthermore, teachers’ planning time provided a forum for teachers to display the rationales underlying their decision making, rationales that are usually hidden from view, especially from the view of a researcher. Teachers’ normally hidden planning process was thus rendered visible, and hence open to investigation.
Racial Differences in the Formation of Postsecondary Educational Expectations: A Structural Model
Authors: Museus Samuel D. , Harper Shaun R. , Nichols Andrew H.
Published: November 2021

Background

Educational attainment is associated with a plethora of positive economic and social implications for individuals, institutions, and the broader society. One factor that has been identified as an important predictor of students’ educational attainment is their educational expectations. Thus, understanding how educational expectations are shaped is important to comprehending how success can be fostered among students from diverse racial backgrounds.

Purpose of the Study

This quantitative study is aimed at understanding the process by which students from various racial backgrounds cultivate and reformulate their educational expectations during the high school years. Three research questions were explored in this study: (1) How do various academic and interpersonal factors directly affect students’ educational expectations? (2) How do academic and interpersonal factors indirectly affect students’ educational expectations via their self-perceptions? and (3) How do those effects vary across different racial groups?

Populations and Participants

The National Education Longitudinal Study (NELS) survey was first administered to students in the spring of eighth grade, and the first two follow-up surveys were administered in the spring of those students’ 10th- and 12th-grade years. Students who participated in the NELS surveys from the base year to the second follow-up (88:92) were included in the omnibus analysis, resulting in an overall sample size of 12,144. That sample was divided into Asian (n = 764), Black (n = 1,041), Latina/o (n =1,444), Native American (n= 399), and White (n = 7,626) subsamples, and a parallel analysis was conducted to allow for the comparison of effects across various racial subpop-ulations.

Research Design

Using a pretest-posttest design and structural equation modeling techniques, we created a structural model and examined how academic and interpersonal factors directly and indirectly, via self-efficacy and locus of control, influence students’ educational expectations. Particular attention is given to how those effects vary across racial subpopulations.

Conclusions and Recommendations

Relationships between the results of this inquiry and earlier studies are complex, with some of our findings confirming and some contradicting those of other researchers. The results of this analysis indicate that the process by which students formulate and reformulate their educational expectations during the high school years varies across racial groups. Recommendations for future research involve considering racial, gender, socioeconomic, and other differences in examining students’ educational expectations and outcomes. We also recommend that future research focus on understanding the reasons why such racial differences exist.
Socially Constructed Self-Regulated Learning and Motivation Regulation in Collaborative Learning Groups
Authors: Järvelä Sanna , Järvenoja Hanna
Published: November 2021

Background/Context

Most of the earlier empirical findings deal with motivation regulation in individual learning situations. This study identifies higher education students’ socially constructed motivation regulation in collaborative learning and stresses that regulation of motivation is crucial in socially self-regulated learning because motivation is constantly shaped and reshaped as the activity unfolds.

Purpose of Study

The purpose of the study is to identity higher education students’ socially constructed motivation regulation in collaborative learning This was studied by collecting data about the students’ (N = 16) experiences of situation-specific social challenges in collaborative learning groups and observing what the students do to overcome these challenges.

Research Design

The study is a qualitative, multimethod study. Three methods—namely, adaptive instrument, video-tapings, and group interviews—were used to assess the individual- and group-level perspectives on those situations that the students felt were challenging and thus possibly activated joint regulation of motivation.

Conclusions

Motivation regulation can be identified as a socially constructed activity, and the importance of regulation of motivation in socially self-regulated learning is discussed.