bluuebunny/crossref_metadata_2025 huggingface dataset:
Hospital Based Prevalence of Smoking Among Surgical Patients in Tertiary Care Hospitals of Karachi Pakistan
Authors: Nazir Mohsin , Rehman Azhar , Rashid Saima , Salim Bushra , Baig Tanveer , Karam Khan Karima
Published: January 2023

Objective: To determine the prevalence of smoking and to evaluate the knowledge about preoperative smoking cessation in patients coming for elective surgery.
Method: The cross-sectional study was conducted from July 30, 2019, to March 17, 2020, in the preoperative anaesthesia assessment clinic and surgical wards of Aga Khan University Hospital, Civil Hospital Karachi, and Abbasi Shaheed Hospital, Karachi, and comprised all patients of either gender aged >12 years scheduled for elective surgery having American Society of Anaesthesiologists physical status I-IV. Data was analysed using Stata 13..
Results: Of the 811 patients, 478(59%) were male and 333(41%) were female. The overall mean age was 43.4±16.4 years and mean BMI was 25.0±5.8kg/m2. There were 164(20.2%) smokers in the sample. The overall knowledge about preoperative smoking cessation was significantly associated with the level of education and gender (p<0.05).
Conclusion: Smoking in surgical patients was about one-fifth of the overall sample, and knowledge related to preoperative smoking abstinence was significantly associated with educational status and gender.
Key Words: Prevalence of smoking, Surgical patients, Knowledge of smoking abstinence.
MENDORONG EFEKTIVITAS PELAYANAN JEMAAT DI GEREJA BETHEL (PENTAKOSTA) JEMAAT SION KEMIRI-SENTANI
Authors: Kabanga Lewi , Gainau Markus S. , Wenda Daniel , Talo Amsi
Published: January 2023

Kegiatan pengabadian ini bertujuan untuk membantu jemaat Tuhan di Gereja Bethel (Gereja Pentakosta) Kecapi Sion, Kemiri-Sentani dalam menyelesaikan penyebab kevakuman ibadah yang sering dialami. Metode yang digunakan dalam melakukan kegiatan yang kemudian dibagi dalam beberapa bagian yaitu observasi, dan IDI (Interview mendalam), kegiatan inti, dan dokumentasi/publikasi. Hasil dari kegiatan pengabdian masyarakat ini menunjukkan bahwa ada 2 penyebab terjadinya kevakuman beribadah yang dialami gereja yaitu (1) keadaan alam dan (2) ketidakkonsistenan gembala. Cara altrnatif yang diterapkan untuk mencegah kevakuman beribadah adalah (1) Tim membuat meja jamuan yang berfungsi ganda untuk menjamu tamu gereja sesuai dengan kebiasaan Papua dan untuk pencegah genangan air di hakam gereja (2) Tim akan membantu jemaat dengan cara membangun koneksi dan kerjasama dalam memberikan pelayanan ke gereje ini.
MAKNA TEOLOGIS MENGUMPULKAN HARTA DI SURGA BERDASARKAN MATIUS 6:20
Authors: Gulo Fenius
Published: January 2023

If people do not carefully read Matthew 6:20, the essay about Jesus' expression in the phrase "gathering up treasures in heaven," many will assume that what is meant is accumulating the world's wealth in the form of material such as food, clothing, gold, silver and various other things related to material things. However, after conducting an investigation based on the biblical study approach, He gave an essay that accumulating treasure in heaven is an act or act of pleasing God by living rightly and doing His will according to God's Word. It is not wrong to look for worldly treasures in fulfilling all the necessities of life, as long as it is in a good way and according to God's will. Therefore, it must be realized that all worldly treasures in the material form will disappear, while treasures in heaven are eternal and provide eternal happiness to their owners.
ARGUMENTASI TEOLOGIS TENTANG DAMPAK DOSA TERHADAP PIKIRAN
Authors: Riswan Riswan , Ndruru Fasmani
Published: January 2023

Pikiran yang merupakan keunikan dari pada manusia itu tidak terlepas dari pada dosa pasca kejatuhan kedalam dosa.  Penganut empirisme yang selalu menjadikan pengalaman sebagai tolak ukur atas kehidupan manusia menolak akan dampak tersebut dengan pandangan bahwa, walaupun manusia bersifat fana, manusia bersifat netral secara moral. Dampak dosa terhadap pikiran adalah manusia tidak bisa menemukan kebenaran dengan akal sehatnya melainkan ia selau gagal dalam melakukanya. Kematian Rohani manusia menimbulkan kengerian yang begitu luar biasa menjijikan dan mendukakan hati Tuhan. Namun manusia duniawi tidak mempedulikan semuanya itu, melaikan berbangga atas dosa dan kelaliman yang telah diperbuatnya. Pembahasan mengenai topik ini disajikan secara deskriptif berdasarkan argumentasi secara teologis menurut pandangan beberapa ahli yang dirangkum dalam sebuah paparan secara preskriptif.  Sebagai hasil yang didapatkan bahwa, dosa telah membuat seluruh aspek kehidupan manusia mengalami hal yang mengerikan. Ada Tiga aspek yang di pengaruhi oleh pikiran yang berdosa yakni, “manusia tidak lagi mengakui keberadaanya sebagai makhluk ciptaan Tuhan (Aspek Spritual), Manusia menjadi krisis akan kebaikan dan tidak mungkin mencari Allah ( Aspek Moral) dan manusia lebih muda salah mengerti, lebih cepat menghakimi dan lebih memilih untuk menyendiri dari pada bergaul dengan orang lain (aspek sosial).
KOINONIA DALAM SURAT FILEMON 1:6: SUATU ANALISIS TERHADAP RELASI FILEMON DAN ONESIMUS
Authors: Tantama Epafroditus Cahya
Published: January 2023

Persekutuan (Yun.: koinonia) sebagai salah satu tugas panggilan gereja seharusnya dapat menjembatani perbedaan dan mengubahkan kehidupan sosial. Namun, kenyataan yang terjadi justru sebaliknya. Persekutuan Kristen terkadang menjadi tertutup bagi orang yang memiliki perbedaan status sosial tertentu. Tulisan ini bertujuan untuk menunjukkan bahwa persekutuan di antara orang percaya mampu meruntuhkan sekat-sekat penghalang dan mengubahkan kehidupan. Melalui penelitian kualitatif yang menggunakan metode kritik sosial dan tekstual atas Surat Filemon dengan dibantu beberapa literatur terkait, diperlihatkan pemahaman bahwa seorang budak yang bersalah, bertobat dan kembali kepada tuannya tetap diperhitungkan di dalam persekutuan Kristen dan dilibatkan dalam pelayanan. Pada akhirnya, tulisan ini menyimpulkan bahwa persekutuan Kristen yang sehat dapat mentransformasi kehidupan. Di dalam persekutuan Kristen ada penerimaan satu sama lain dan memberi ruang bagi semua orang dengan status sosial yang berbeda untuk mengaktualisasikan dirinya dalam kehidupan gereja, termasuk dalam kehidupan sosial masyarakat.
PERAN ORANGTUA DAN PEMBINA REMAJA KRISTEN TERHADAP FENOMENA PERILAKU REMAJA CITAYAM
Authors: Widjaja Linda , Hermanto Yanto Paulus , Tatang Josep
Published: January 2023

The role of parents and youth coaches in the growth and development of adolescent life is significant. This is because there is much news about teenage problems, such as teenage fights, school shootings, alcohol-related accidents, drugs, early pregnancy outside marriage, and teen suicide. Juvenile delinquency due to dropping out of school and lack of parental attention is also often a problem. Adolescent problems can extend to whole communities, schools, churches, cities, and countries. Teenagers at their critical age are trying to find their identity after going through childhood to adult humans. All positive and negative influences in teenagers' lives tend to be easily absorbed, studied, and carried out, even though many are developed as innovations from their creativity. The presence of the adolescent phenomenon from Citayam has recently become the author's interest to examine the role of parents and youth coaches in responding to their influence on teenagers as the next generation of the Kingdom of God. The phenomenon of Citayam youth brings positive and negative impacts and brings a new challenge for parents and youth coaches to answer the challenges of today's youth. This research was made using a qualitative literature study from the Bible, books about teenagers, articles, and social media content about the Citayam youth phenomenon.
KESETIAAN NABI YESAYA DAN RELEVANSINYA BAGI PENGABDIAN HAMBA TUHAN MASA KINI
Authors: Nggebu Sostenis , Agustina Viceta Pomida
Published: January 2023

Problem yang dikaji dalam artikel ini untuk menjawab pentingnya para hamba Tuhan tetap setia melayani pekerjaan Allah yang dipercayakan kepadanya. Kesetiaan dalam melayani pekerjaan Allah merupakan karakter pelayan yang dituntut dari Allah sejak awal mengabdi hingga mencapai garis finis. Metode yang digunakan dalam artikel ini adalah metode studi literatur. Hasilnya, memperlihatkan bahwa kesetiaan seorang hamba Tuhan mencerminkan karakter pribadinya. Ia seorang yang memegang kuat komitmennya di hadapan Allah sebagaimana diperlihatkan Nabi Yesaya. Sekalipun mendapat penolakan dari para pemimpin dan masyarakat Yehuda, Yesaya tetap setia bernubuat sampai akhir hayatnya. Model hamba Tuhan seperti ini dibutuhkan dalam pelayanan gerejawi masa kini untuk melayani jemaat agar tetap setia dalam imannya sekalipun berhadapan dengan gejolak dan tantangan pada masa kini.
REVITALIZING HARVEST THEOLOGY FOR AN EFFECTIVE MISSION TODAY
Authors: Silalahi Frans M. H.
Published: January 2023

There is a decline in the population of Christians in the world from 2010 to 2020, and the primary cause is the slowing down of mission and evangelization efforts.  Christians no longer see the urgent need of reaping the harvest of souls.  Therefore, there is a need for Harvest Theology based on a solid biblical foundation to revitalize today’s mission. This paper uses exploratory and explanatory research methods to come up with a conclusion that churches need to develop Harvest Theology that creates effective strategies as well as focuses resources to reach receptive people; especially among the unreached people group. Harvest Theology is a counter to search theology that emphasizes finding the lost and multiplication of churches. Harvest Theology is very important to be revitalized because of the declining percentage of Christians in the period 2010 to 2020. Through exploratory and explanatory research methods, the author tries to convince readers that Harvest Theology is based on a solid biblical foundation and is vital to revitalizing today's mission. In revitalizing Harvest Theology, we need to develop mission strategies that focus on receptive people, which will give a great harvest in today's mission.
HAVACILIK YÖNETİMİ ÖĞRENCİLERİNİN REZERVASYON SİSTEMİNE İLİŞKİN ALGILARI: METAFOR ANALİZİ ÖRNEĞİ
Authors: DOĞAN Murat Ahmet , ŞİMŞEK Zafer , AYVALIOĞLU Asena
Published: January 2023

Sivil hava taşımacılığı endüstrisi dünya ekonomisine katkıda bulunurken teknolojik yenilikleri takip ederek gelişimini sürdürmektedir. Teknoloji yoğunluğu yüksek bu endüstride sistem performanslarının artırılması önemli olup, ürün sunumunda kullanılan en önemli araç rezervasyon sistemleridir. Bu bağlamda, sözü edilen endüstride kariyer planlaması yapan havacılık yönetimi öğrencilerinin rezervasyon sistemleri hakkında bilgi ve farkındalık düzeyleri araştırılmaktadır. Bu çalışmanın amacı havacılık yönetimi öğrencilerinin rezervasyon sistemleri kavramına ilişkin algılarının metafor analizi yöntemiyle araştırılması ve oluşan metaforların ortak özellikleri bakımından kavramsal kategoriler altında toplanmasıdır. Çalışmanın örneklemi Samsun Üniversitesi Sivil Havacılık Yüksekokulu Havacılık Yönetimi bölümünde öğrenim görmekte olan 123 öğrenciden oluşmaktadır. 2021-2022 Bahar döneminde veri toplama süreci gerçekleştirilmiştir. Öğrencilere iki bölümden oluşan bir rezervasyon sistemleri metafor algısı formu uygulanmıştır. Bu formun ilk bölümü demografik bilgilerden oluşmaktadır. İkinci bölümü ise katılımcıların rezervasyon sistemleri algısını ölçmek için “Rezervasyon sistemleri … gibidir/benzerdir, çünkü …” ifadesini içeren açık uçlu tek sorudan oluşmaktadır. Bu formun birinci bölümünden elde edilen veriler tanımlayıcı istatistikler ile analiz edilirken ikinci bölümünden elde edilen metafor verileri de içerik analizi yöntemi ile analiz edilmiştir. Katılımcılardan elde edilen verilere göre 121 farklı metafor ortaya çıkmıştır. İlk değerlendirmeler sonrasında 111 farklı metafor anlamlı bulunmuş ve bu metaforlara ait açıklamalar içerik analizine dahil edilmiştir. Bu metaforlar altı kategori içerisinde yapılandırılmıştır. Bu kategoriler içerdikleri metafor yoğunluğuna göre sırasıyla şu şekildedir: (1) Yer tutma, (2) Sistem, (3) Fayda, (4) Hizmet, (5) Garanti ve (6) Kolaylıktır. Çalışmanın bulgularına göre öğrencilerin rezervasyon sistemleri algısının güvenli, kolaylık sağlayan ve hizmet odaklı kullanım üzerine odaklandığı görülmektedir.
Estudio piloto de los factores socio-culturales y su influencia en el estado emocional de las personas con VIH. Validación de instrument
Authors: Romero Charles , Parrales Rosado Roxana , Jaramillo López Jazmín
Published: January 2023

Introducción: Durante los procesos de investigaciones, luego de establecer el diagnostico situacional, es importante enfocarse en estudios bibliométricos para poder confirmar las hipótesis que se plantean durante un estudio investigativo, en muchas de las ocasiones se complica porque no existe la cantidad suficiente de instrumentos para llevar a cabo la investigación. Objetivos: evaluar la validez, pertenencia y confiabilidad del instrumento que permitirá determinar si los factores psicosociales influyen en el estado emocional del paciente con VIH. Materiales y métodos: Se utilizó una investigación de tipo: cuantitativa, prospectiva, de campo, de corte transversal, tipo analítico descriptivo, se utiliza una población de estado socioeconómico medio, hombres y mujeres que residen en el Cantón Milagro con diagnóstico de VIH, edades que van desde los 18 años a los 65 años de edad. Resultados: La validación para el instrumento propuesto, obtiene una calificación total de 87,92, lo que se considera que el cuestionario según los expertos es: Muy confiable. La siguiente validación se realiza mediante el análisis estadístico por Alfa de Cronbach, y se obtiene una puntuación de 0,91, lo que denota que el instrumento se encuentra dentro de la escala de Bueno – Alto, en confiablidad. Conclusiones: Se concluye que el instrumento es de buena confiabilidad, es útil y pertinente para los fines establecidos, el cual responde al objetivo planteado, determinar si los factores psicosociales influyen en el estado emocional del paciente con VIH, lo que determinó que los factores encontrados son: laborales, económicos, personales y culturales.
Validación de instrumento para identificar la calidad de vida en pacientes con insuficiencia renal crónica, que reciben hemodiálisis
Authors: Parrales Rosado Roxana , Romero Charles , Jaramillo López Jazmín
Published: January 2023

Introducción: El impacto psicológico que genera una enfermedad crónica en el ciclo vital de los pacientes, y en cierto modo, en el propio curso de la enfermedad, estará relacionado con el tipo de estrategias de afrontamiento ante los miedos, las preocupaciones, los recuerdos negativos, los pensamientos y las sensaciones ante el tratamiento y en relación al futuro. Objetivos: Validar el instrumento cuantitativo para determinar la calidad de vida del paciente con insuficiencia renal crónica que recibe hemodiálisis y Analizar la calidad de vida del paciente con IRC. Materiales y métodos: la presente investigación se realizó mediante la modalidad de estudio cuantitativa, es de corte transversal, de tipo descriptiva. Se trabajó con una muestra piloto de 15 personas, que acudieron a tratamiento de hemodiálisis en los meses de enero a diciembre del 2021 Resultados: Se aplicó el coeficiente Alfa de Cronbach que permite identificar la confiabilidad o validez del instrumento a emplearse, se obtiene un resultado de 0.75, es decir una confiabilidad aceptable o buena para su aplicación, según juicio de expertos se obtiene una puntuación de 91,33 considerado como confiable. Conclusiones: Las conclusiones establecidas manifiestan que en el proceso de conllevar esta enfermedad los pacientes, se ven afectado de muchas maneras no solo a nivel físico, sino también a nivel emocional, por ello, los estados emocionales más frecuentes que intervienen son la ansiedad, el estrés y la depresión, además también tienen que ver con los sentimientos, las preocupaciones, que alteran de manera negativa su psiquis y sus emociones, afectando de manera negativa su calidad de vida.
Cost of Equity Capital and the Determinant: A Study in Industrial Firms in Indonesia
Authors: Askotamiya Chici
Published: January 2023

This research aims to analyse the effects of accounting information asymmetry, market risk, audit quality, and company size on cost of equity capital on industrial companies registered in Indonesia Stock Exchange from 2017 to 2021. Data analysis techniques consist of descriptive statistics, classical assumption testing, and hypothesis testing with multiple linear regression analysis method. The test results show that market risk and company size has positive and negative effect on the cost of equity capital respectively, while accounting information asymmetry and audit quality does not affect the cost of equity capital. The limitation in this study is that the measurement of audit quality variables is only obtained by the standard of public accounting firm, and there are still 62,7 percent of other factors outside the independent variable which can affect the value of the company’s cost of equity capital.
Clinical Outcome of Intravascular Ultrasound Guided Percutaneous Coronary Intervention of Isolated Ostial Left Anterior Descending Artery Lesions
Authors: Fayed Hany , Elgendy Khaled , Barrada Ismail R
Published: January 2023

Purpose: Despite recent advances in interventional cardiology procedures, isolated ostial left anterior descending (LAD) lesions remain a challenge in cardiology. Due to the probability of left main (LM) affection, an LM bifurcation stenting technique may be required in certain individuals. So we evaluated result of Intravascular Ultrasound (IVUS) guided percutaneous coronary intervention (PCI) in isolated LAD coronary artery lesions, either by crossing over the ostium or not, with a focus on major adverse cardiovascular events (MACE).

Methodology: Our prospective study from January2021 to November 2022 included 79 isolated ostial LAD patients with Ostial LAD stenting (OS) or LM to LAD cross-over (CO) stenting at the National Heart Institute. As per the recommended guidelines, the participants were divided into two groups: the first one had IVUS guided PCI and Group (2) had Angiography guided PCI. The data was collected and statistically analyzed with SPSS 23.0 program.

Findings: No statistically significant difference was present between the groups regarding socio-demographic or clinical data (P-value > 0.05). It was discovered that an increase in Rotablator use, a decrease in Fluoroscopy time (min), a decrease in Contrast volume (ml), and a decrease in PCI duration (min) in patients who had IVUS guided PCI, with statistically significant difference when compared to other group who had Angiography guided PCI (P-value < 0.05). In addition, it was discovered that an increase in the necessity for a cross-over stenting method in group (1), with no statistically significant difference (P-value > 0.05). High prevalence of mortality and morbidity among IVUS guided PCI patients was present with statistical significance regarding TVR (P-value < 0.05).

Recommendations: IVUS can offer valuable information on vascular lumen, plaque features, stent deployment, & device failure causes. As a result, IVUS-guided PCI may enhance clinical impact among participants, particularly those with complicated coronary lesions & those at high risk. Further reduction in IVUS’s cost, cardiologists’ education and enhancing IVUS use at PCI should be adapted next.
Опыт исследования дифференциации районов Москвы по социально-экономическим показателям
Authors:   Институт народнохозяйственного прогнозирования РАН, Ноздрина Н.Н. , Макагонов П.П.
Published: January 2023

Рассмотрены особенности пространственного распределения социально-экономических характеристик районов Москвы в старых границах. Проведен кластерный анализ районов с учетом и без учета расстояния до центра города. Показано пространственное распределение кластеров районов, объяснены особенности сочетания различных диапазонов изменения показателей.
Состояние и направления развития лесного комплекса Республики Коми
Authors: Шишелов М.А.
Published: January 2023

В статье представлен анализ современного состояния лесного комплекса Республики Коми, предложены стратегические направления его развития. Результаты исследования выявили крайне низкий уровень инновационной активности в лесной промышленности региона. В последние тридцать лет развитие шло по экстенсивному пути увеличения объёмов производства и экспорта лесных товаров первичных и средних уровней передела, а доля продукции с высокой добавленной стоимостью в товарно-отраслевой структуре измерялась на уровне статистической погрешности.
Возможности трансформации налоговой системы с учетом отраслевых особенностей
Authors:   Институт народнохозяйственного прогнозирования РАН, Ордынская Е.В.
Published: January 2023

В статье рассматриваются проблемы, связанные с тяжестью налоговой нагрузки в отношении предприятий различных отраслей. Вопросы взаимозависимости уровня налоговой нагрузки и рентабельности в различных сферах деятельности значительно влияют на развитие отдельных отраслей народного хозяйства. Налоговые инструменты могут выступать в качестве катализаторов роста и развития предприятий, так и тормозить указанные процессы. При этом при анализе налогового бремени и рентабельности необходимо учитывать не только отраслевые особенности, но и региональную специфику. Кроме того, в кризисных условиях особое значение приобретает анализ финансового результата деятельности предприятий, изучение динамики соотношения прибыльных и убыточных предприятий. Также, в статье рассматриваются вопросы использования налоговых льгот во взаимосвязи с вышеуказанными факторами.
Демографические тенденции и государственная демографическая политика: Россия и зарубежный опыт
Authors:   Институт народнохозяйственного прогнозирования РАН, Андронова Л.Н. , Ланцова Н.М. ,   Институт народнохозяйственного прогнозирования РАН
Published: January 2023

В статье представлен обзор основных демографических тенденций в России, странах СНГ, а также в Центральной и Восточной Европе. Дается характеристика демографической политики, проводимой в России, рассматривается международный опыт государственных мер поддержки семей с детьми и повышения рождаемости в отдельных странах Центральной и Восточной Европы. Описывается успешный региональный опыт Сахалинской области по стимулированию рождаемости, который может быть востребован в других регионах страны. Обсуждаются долгосрочные демографические прогнозы численности населения в России и их предпосылки.
Síndrome de Budd Chiari secundario al síndrome antifosfolipídico y lupus eritematoso sistémico en una adolescente: reporte de un caso
Authors: Atamari-Anahui Noé , Domínguez-Rojas Jesús , Ruiz-Solsol Luis , López-Turpo Maryori , Castillo-Delgadillo Amarilis , Quiñonez Saif David , Campano William
Published: January 2023

El síndrome de Budd-Chiari es causado por una obstrucción del flujo sanguíneo del hígado. Los casos publicados del síndrome antifosfolípido asociado a SBC son limitados en la población pediátrica. Reportamos el caso de una adolescente de 15 años que presentó fiebre, ascitis y hepatoesplenomegalia. En la ecografía Doppler hepática se observó ausencia de flujo en la vena hepática derecha y media, y en la vena cava inferior. En la tomografía abdominal se observó una extensa trombosis de la vena cava inferior. Durante la hospitalización se le diagnosticó SAF y lupus eritematoso sistémico. Se le administró tratamiento con heparina no fraccionada, heparina de bajo peso molecular y anticoagulantes. El síndrome de Budd-Chiari secundario al síndrome antifosfolípido es una enfermedad potencialmente mortal. El diagnóstico y el tratamiento oportunos permiten mejorar la calidad de vida del paciente.
Adverse reactions to antituberculosis drugs presenting as DRESS syndrome and acute liver failure
Authors: Carlin Ronquillo Andrea , Alvizuri Gómez Claudia , García Encinas Carlos
Published: January 2023

Drug induced liver injury (DILI) can be can be triggered by many medications including antituberculosis drugs. We present the case of a 37-year-old woman with a smear- positive pulmonary tuberculosis who started treatment with first-line antituberculosis drugs and 4 weeks later presented jaundice, somnolence and a morbilliform generalized rash with progressive neurologic deterioration which had a fatal outcome. Antituberculosis drugs can cause DILI in 2 to 28% of patients and drug reaction with eosinophilia and systemic symptoms (DRESS syndrome) in 1.2%. Acute liver failure (ALF) can occur in 35% of patients with DILI with an overall mortality of 9.7%. If the ALF is unresponsive to medical treatment, liver transplantation has shown promising results and can avoid progression of complications. DILI can be a serious medical condition in patients receiving antituberculosis drugs. If ALF develops and is unresponsive to medical treatment, liver transplantation should be considered as the treatment of choice.
Tratamiento de hepatitis C crónica en pacientes con enfermedad renal: aportes a la Guía de Práctica Clínica del Seguro Social de Salud del Perú (EsSalud)
Authors: Gonzales-Zamora Jose Armando , Ponce-Rosas Linda , Alave-Rosas Jorge
Published: January 2023

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Normal transaminases in obese patients with metabolic associated steatohepatitis (MASH): a cohort of Peruvian patients
Authors: Lozano Adelina , Carrillo-Ng Hugo , Castro Cesar , Lozano Zenaida , Saavedra Lil , Salinas Gustavo
Published: January 2023

Introduction: Metabolic associated steatohepatitis (MASH) is one of the most frequent causes of chronic liver disease. Liver transaminases are important biomarkers to measure liver injury, however, a proportion of patients with MASH may present with normal levels of transaminases. The levels of serum transaminases may not correlate with the severity of histopathological changes. Objective: We aimed to identify the frequency of normal transaminases in obese patients with MASH, as well as to describe the clinical, biochemical and histological characteristics in this specific group of patients. Materials and methods: A retrospective cross-sectional study was conducted in the bariatric surgery service of a private clinic. Obese patients older than 18 years with a body mass index (BMI) >30Kg/m2 and 2 co-morbidities undergoing a gastric sleeve surgery were included. Measurement of biochemical routine laboratory exams was performed. Insulin resistance was calculated using the homeostasis evaluation model (HOMA-IR). All patients underwent liver biopsies prior to surgery and the diagnosis of MASH was based on the Brunt criteria. Results: 159 obese patients with MASH were included, of which 47.2% had normal transaminases and 52.8% elevated transaminases. Factors associated with alteration in transaminases were: being male OR=4.02 (95% CI: 2.03-7.96; p<0.01), diagnosis of type 2 diabetes mellitus OR=4.86 (95% CI: 1.97- 11.95; p<0.01) and levels of GGT >50 IU/L OR=7.50 (95% CI: 3.40-16.56; p<0.01). The values of HOMA-IR and GGT were significantly higher in the group of high transaminases (p<0.01). Differences in the degree of fibrosis were not associated with transaminases levels. Conclusion: In conclusion we found that the frequency of normal transaminases was 47.2% in obese patients with MASH. Factors associated with elevation in liver enzymes were being male, diagnosis of diabetes mellitus and elevation in GGT levels. The degree of fibrosis was not associated with elevations in liver transaminases. These findings suggest that transaminases levels alone are not accurate markers to assess liver injury, as they do not necessarily correlate with histological liver damage.
Patrones de detección de Helicobacter pylori y lesiones relacionadas mediante protocolo Sydney en una población de Antioquia, Colombia
Authors: Sanchez Londoño Santiago , Guevara Casallas Gonzalo , Niño Sebastián , Arteta Cueto Ariel , Marcelo Escobar René , Camilo Ricaurte Juan , Cardona Catalina , Esteban Erebrie Faruk Esteban , Londoño Castillo Juliana
Published: January 2023

Objetivos: Se buscó determinar si las endoscopias que cumplieron el protocolo Sydney en una población de Antioquia tuvieron una detección mayor de H. pylori y sus lesiones asociadas que las endoscopias que sólo tomaron muestras de antro. Materiales y métodos: Realizamos un estudio retrospectivo, trasversal y descriptivo. Se incluyeron pacientes adultos sometidos a endoscopia superior. Se dividieron los pacientes en dos grupos según si se siguió o no el protocolo Sydney y se midió la frecuencia de detección de H. pylori, y lesiones premalignas. Resultados: Se incluyeron 261 participantes, a 88 se les tomó el protocolo de Sydney y a 173 se les tomaron muestras exclusivamente de antro gástrico. La indicación principal de endoscopia fue dispepsia (35,6%). La detección de H. pylori, gastritis atrófica y metaplasia intestinal fue del 36,4%, 19,3% y 20,5% respectivamente en el grupo Sydney, y 30,1%, 11,6% y 9,8% en el grupo control. En el grupo Sydney, la detección de H. pylori fue mayor en antro y cuerpo (26,1%) que en antro (6,8%) o cuerpo (3,4%) por separado. La detección de gastritis atrófica y metaplasia intestinal fue mayor en antro solamente (10,2% y 11,4% respectivamente) que en antro y cuerpo o cuerpo por separado. Conclusiones: La omisión del protocolo Sydney reduce la detección de H. pylori, gastritis atrófica y metaplasia intestinal en un 9,4%, 29,4% y 27,7% respectivamente. Se debe implementar el protocolo sistemáticamente en todo centro de endoscopia digestiva.
Eje cerebro intestino microbiota. Importancia en la práctica clínica
Authors: Bustos-Fernández Luis María , Hanna-Jairala Ignacio
Published: January 2023

El eje cerebro-intestino-microbiota es un complejo bidireccional que comunica al sistema nervioso central con el aparato digestivo. Las alteraciones en la composición de la microbiota intestinal se han relacionado con la presencia de enfermedades digestivas y extradigestivas tales como las enfermedades neuropsiquiátricas.  La disbiosis predispone a la aparición de alteraciones en la permeabilidad intestinal, lo cual facilita la liberación de neurotransmisores y citoquinas que generan las condiciones propicias para que aparezca un estado conocido como neuroinflamación, que parece ser clave en la fisiopatogenia de las enfermedades neuropsiquiátricas. En virtud de estos datos, la modulación de la microbiota a través de cambios en la dieta, antibióticos y probióticos, podría ser una alternativa útil, no sólo para el tratamiento de enfermedades digestivas sino también de trastornos extra digestivos como las enfermedades neuropsiquiátricas.
Influences of Organic Additives on Asymbiotic Seed Germination of Dendrobium cruentum Rchb. f. for In Vitro Micropropagation
Authors: Samala Sainiya , Thipwong Jaturon
Published: January 2023

Dendrobium cruentum Rchb. f., a commercial orchid in Thailand, faces the risk of extinction and should be conserved, and propagated for commercial. Therefore, the aim of this research was to identify a suitable VW medium supplemented with organic additives for the micropropagation of D. cruentum through asymbiotic seed germination. The VW media supplemented with separate organic additives (coconut water (CW) (100 mL/L), ‘Hom Thong’ banana homogenate (BH) (1000 mg/L), and potato homogenate (PH) (1000 mg/L) or its combination was determined, and the seed germination rate (%), protocorm formation, and plantlet development were observed. The results showed that a combination of BH and PH resulted in the highest seed germination (94.69 ± 1.55 %) when compared to basal VW (control). Protocorm formation was highest with CW alone (47.38 ± 7.17 %) and a combination of CW and PH (52.13 ± 6.20 %). Additionally, after 10 weeks of culture, supplementation with BH yielded the highest number of plantlets. However, after 24 weeks of culture, each organic additives gave the different developments of healthy plantlets. To investigate suitable potting media for acclimatization of well-grown plantlets in greenhouse conditions, 2 pieces of foam, dried coconut husk, and a combination of peat moss: Sphagnum moss: Pumice: Perlite (3:1:1:1) were investigated. The highest survival rate percentage was found in foam-planted plantlets (80 %). Ultimately, the effectively simple mediums containing organic additives and a one-step protocol were provided for the micropropagation of D. cruentum via seeds, and the derived information could be used for D. cruentum conservation and production.
HIGHLIGHTS

The effects of organic additives on asymbiotic seed germination for in vitro micropropagation of Dendrobium cruentum Rchb. f. was firstly reported
The media supplemented with organic additives yield significantly the highest seed germination, protocorm formation, and plantlet formation and development of D. cruentum when compared to basal media
In greenhouse conditions, 2 pieces of foam gave the highest survival rate percentage of plantlets (80 %)
The practical and beneficial media supplemented with organic additives for micropropagation of D. cruentum was provided

GRAPHICAL ABSTRACT
Tumor renal híbrido y su espectro atípico: Reporte de caso y revisión de la literatura
Authors: Sánchez-Gómez Leidy Cristina , Cruz-Cruz Nadia Ruth , Arroyo-López Norma Patricia
Published: January 2023

Caso clínico: El tumor renal híbrido se define como aquella neoplasia cuyos componentes están dados por la presencia de oncocitos (oncocitoma) y células cromófobas cuyo diagnóstico preoperatorio es un reto por la gran similitud con el oncocitoma típico. Sus modalidades de presentación incluyen la hereditaria y esporádica, siendo la primera la más frecuente asociándose al compromiso de otros órganos como la piel y el pulmón. Implicaciones clínicas: Presentamos el caso de una paciente femenina de 9 años de edad, estudiante de primaria, a quien de manera incidental se le encuentra masa en flanco izquierdo, no dolorosa a la palpación, fija, de aproximadamente 8 cm, por lo que se realiza ultrasonido, tomografía abdominal así como angiotomografía renal donde se confirma la presencia de una gran masa renal izquierda bien definida, heterogénea por área de necrosis central, sin evidencia de infiltración a estructuras adyacentes o invasión vascular cuyo reporte histopatológico arroja oncocitoma renal hibrido, por lo que es llevada a nefrectomía total laparoscópica, presentando adecuada evolución en su seguimiento.
Relevancia: Familiarizarnos con el espectro de masas renales en los escolares es de vital importancia ya que son neoplasias de curso benigno, lo que evita el uso de medidas innecesarias.
Conclusión: La rápida identificación permite intervenciones quirúrgicas oportunas con menor morbilidad en los pacientes, por lo que es importante que los diferentes especialistas conozcan sus hallazgos imagenológicos.
Presencia de litiasis en una serie de 2658 injertos renales funcionantes. Experiencia de un solo centro
Authors: Vázquez- Martul Dario , López- Fernández Alicia , Lancina-Martín Juan Alberto , Fern´ández- Rivera Constantino , Altez-Fernández Carlos , Salgado-Novoa Jorge , Ponce Díaz-Reixa José Luis , Chantada-Abal Venancio
Published: January 2023

Objetivo: El objetivo de nuestro estudio es conocer los datos de aparición de litiasis renal y sus características en los pacientes trasplantados renales con injertos funcionantes en nuestro centro.
Diseño: Se llevó a cabo un estudio retrospectivo de los trasplantes realizados en nuestro centro desde enero de 1981 hasta diciembre de 2019. Se seleccionaron aquellos con injertos funcionantes y en los que se haya diagnosticado patología litiásica. Se recogen las características de esta (localización, composición, forma de presentación y tratamiento realizado).
Resultados: Se encontraron 2658 pacientes con injerto funcionante en nuestro centro. Se reporta una incidencia de patología litiásica del 1.8%. De entre ellos, el 44% se localizaban en el cáliz inferior. En cuanto a la composición, en el 45.4% fue observada la cálcica.
Limitaciones: Es importante destacar que nuestro estudio es observacional y retrospectivo con todas las limitaciones de validez que eso entraña.
Originalidad: Nuestra serie es la más numerosa reportada hasta la fecha en el estudio de la patología litiásica en el trasplante renal. Es también importante resaltar que los datos se extrajeron teniendo sólo en cuenta injertos funcionantes.
Conclusiones: La incidencia de aparición de litiasis es pequeña, pero es una patología a tener en cuenta por las complicaciones que puede conllevar. La localización más frecuentemente observada en nuestra serie fue el cáliz inferior. Aunque estos resultados están respaldados por un gran número de casos, son necesarios estudios de mayor solidez que los refrenden.
Innovative technology for rapid molecular diagnostics: COVID-19 and other respiratory tract infections
Authors: Gujski Mariusz , Snarski Emilian , Dzierżanowska-Fangrat Katarzyna , Hoffman Piotr , Braksator Wojciech , Czech Marcin , Przygodzki Piotr , Walczak Jacek , Pieniążek Izabela , Grys Maciej , Mucha Jacek
Published: January 2023

The outbreak of the COVID-19 pandemic presented the world with many new challenges such as rapid and accurate diagnosis of infected individuals. RT-PCR has become the gold standard in COVID-19 diagnostics, but its limitations are: long turnaround time and the need to be conducted by specialized staff. The need for rapid and easy-to-use diagnostic tests led to the development of ID NOW — a rapid molecular test that provides a COVID-19 diagnosis in less than 15 minutes and can be performed by support staff in point-of-care (POC) locations. It can also detect other infections with similar symptoms, such as influenza or RSV. Due to rapid differentiation between COVID-19 and other infections patients can be isolated quickly and hospital departments operate efficiently. In this publication we present the recommendations for the use of the diagnostic test ID NOW based on clinical research results and opinions of experts in different medical fields.
Türkiye’deki Üniversitelerde Dinler Tarihi Alanında 2021 Yılında Yapılan Yüksek Lisans ve Doktora Tezleri
Authors: SELVİ Ayşe
Published: January 2023

Yeryüzünde var olan bütün dinleri inceleme konusu yapan Dinler Tarihi alanında Türkiye’de son yıllarda yapılan çalışmaların sayısı giderek artmaktadır. Bu minvalde Türkiye’de Dinler Tarihi’nin seyrini konu eden, gelinen noktayı sayısal ve tematik açıdan inceleyip analiz eden çalışmalara ihtiyaç duyulmakta ve uzman akademisyenler tarafından bazı yayınlar yapılmaktadır. Bu çalışma da Türkiye üniversitelerinde uzman akademisyenlerin danışmanlığında Dinler Tarihi alanında yapılmış olan lisansüstü tezlere dair üniversiteler bazında sayısal, tematik birtakım veriler ve kısa değerlendirmeler sunma amacını taşımaktadır. Dinler Tarihi alanındaki tez çalışmalarının geçmişten günümüze sayıca fazlalığı ve çeşitliliği dolayısıyla bu çalışma yalnızca 2021 yılında tamamlanan tezlerle sınırlandırılmıştır. Sosyal Bilimlere ait nitel araştırma yöntemlerinden doküman analizi kullanılarak araştırma gerçekleştirilmiştir. Araştırmanın veri kaynaklarına, Yükseköğretim Kurulu (YÖK) Ulusal Tez Merkezi’nin internet sayfasında yer alan açık ve izinli lisansüstü tezler taranarak ulaşılmıştır. Bu kapsamda ilgili kriterleri karşılayan toplamda 57 lisansüstü tez tespit edilerek çalışmanın veri seti oluşturulmuştur. Çalışma içerisinde bu tezler tematik kategoriler altında tam künyeleri ve Türkçe-İngilizce kısa özetleri listelenerek sunulmuştur.
GLOBAL POSITIONING SYSTEM PRECIPITABLE WATER VAPOR INTERPOLATION USING INVERSE MULTIQUADRIC, ARTIFICIAL NEURAL NETWORK AND INVERSE DISTANCE WEIGHTED
Authors: Chamankar S. , Amerian Y. , Naderi Salim S.
Published: January 2023

Abstract. Precipitable water vapor (PWV) is one of the most critical data in many meteorological departments. This component has great spatial and temporal changes, so the global positioning system (GPS) always seeks to increase the accuracy of estimating the water vapor component in the troposphere. The waves sent by the satellites of this system are delayed due to passing through atmospheric layers such as the troposphere. In this paper, interpolation methods are used to estimate precipitable water vapor. Inverse multiquadric (IMQ) interpolation which is based on radial basis functions, artificial neural network (ANN) method, and inverse distance weighted (IDW) which are the most common method of interpolation in meteorology. A region in North America with 23 GPS stations was randomly selected. Then, the interpolation of precipitable water vapor on a summer day is done using GPS data. The root mean square error value (RMSE) for the IMQ method was the lowest compared to other methods and was equal to 2.11 mm. Finally, using the IMQ interpolation method, a dense map of Precipitable water vapor changes in the troposphere layer is developed for the study area.
LAND SUBSIDENCE SUSCEPTIBILITY MAPPING USING MACHINE LEARNING ALGORITHMS
Authors: Eghrari Z. , Delavar M. R. , Zare M. , Beitollahi A. , Nazari B.
Published: January 2023

Abstract. Land subsidence (LS) is one of the most challenging natural disasters that has potential consequences such as damage to infrastructures and buildings, creating sinkholes, and leading to soil destruction. To mitigate the damages caused by LS, it is necessary to determine the LS-prone areas. In this paper, LS susceptibility was assessed for Kashan Plain in Iran using Random Forest (RF) and XGBoost machine learning algorithms. For the susceptibility analysis, twelve influential factors including elevation, slope, aspect, curvature, topographic wetness index (TWI), groundwater drawdown (GWD), normalized difference vegetation index (NDVI), distance to stream (DtS), distance to road (DtR), distance to fault (DtF), lithology, and land use were taken into account. 291 LS points were used in this study which was divided into two parts of 70% and 30% for training and testing the models, respectively. The prediction power of the models and their produced LS susceptibility maps (LSSMs) were validated using the Root Mean Square Error (RMSE), R-Squared (R2), and Mean Absolute Error (MAE) values. The results showed that the XGBoost had a higher R² equal to 0.9032 compared to that of the RF which was equal to 0.8355. XGBoost model had an RMSE equal to 0.3764 cm compared to that of the RF model which was equal to 0.4906 cm. MAE for the XGBoost model was 0.1217 cm and for the RF model was 0.3050 cm. Therefore, the achieved results proved that XGBoost had better performance in this research for predicting LS values based on the measured ones.
FOREST MODELING AND INVENTORY ESTIMATION USING LIDAR DATA
Authors: Farajelahi B. , Eya F. F. , Arefi H.
Published: January 2023

Abstract. Aerial laser scanners find rapidly growing interest in photogrammetry and remote sensing as an efficient tool for reliable three-dimensional extraction and modelling of forest inventory information. In addition to interactive measurements in 3D point clouds, techniques for automatic extraction of objects and determination of geometric parameters form a high and important research issues (Maas, Bienert et al. 2008). This paper presents a novel approach on the extraction and modelling of individual trees from the Idaho National Forest in the USA and calculation of the statistical estimation for each extracted segment for future analysing. Lidar point cloud contains three-dimensional structure information which is used to estimate the statistical information for each tree segments. In this study, we worked on the raster surface made directly from the LiDAR point cloud and two main models, namely the digital terrain model (DTM) and the digital surface model (DSM), are generated when the point clouds are processed by the filtering method. Then we have used the segmentation techniques to extract the tree segments which is a triggering process that facilitates the extraction of statistical information such as crown diameter, eccentricity, and other additional attributes. The proposed individual tree segmentation method results in 73% correctness, 92% completeness and 81% F1-score.
CROP AND WEED SEGMENTATION ON GROUND-BASED IMAGES USING DEEP CONVOLUTIONAL NEURAL NETWORK
Authors: Fathipoor H. , Shah-Hosseini R. , Arefi H.
Published: January 2023

Abstract. Weed management is of crucial importance in precision agriculture to improve productivity and reduce herbicide pollution. In this regard, showing promising results, deep learning algorithms have increasingly gained attention for crop and weed segmentation in agricultural fields. In this paper, the U-Net++ network, a state-of-the-art convolutional neural network (CNN) algorithm, which has rarely been used in precision agriculture, was implemented for the semantic segmentation of weed images. Then, we compared the model performance to that of the U-Net algorithm based on various criteria.The results show that the U-Net++ outperforms traditional U-Net in terms of overall accuracy, intersection over union (IoU), recall, and F1-Score metrics. Furthermore, the U-Net++ model provided weed IoU of 65%, whereas the U-Net gave weed IoU of 56%. In addition, the results indicate that the U-Net++ is quite capable of detecting small weeds, suggesting that this architecture is more desirable for identifying weeds in the early growing season.
VERTICAL ACCURACY ASSESSMENT OF COPERNICUS DEM (CASE STUDY: TEHRAN AND JAM CITIES)
Authors: Ghannadi M. A. , Alebooye S. , Izadi M. , Ghanadi A.
Published: January 2023

Abstract. Digital Elevation Models (DEMs) are widely utilized in a variety of fields, including, hydrology, geomorphology, and geoscience. The dataset is now openly and freely available to the public, with access permissions for data at 30- and 90-meter resolution having been expanded. The Copernicus DEM is a Digital Surface Model (DSM) that depicts the Earth's surface, which includes structures, infrastructure, and vegetation. This DEM is based on the WorldDEM DSM, which has been altered. The Copernicus DEM's vertical accuracy is assessed in this paper. The study area is in Iran, north of Tehran and west of Jam. The Copernicus DEM is compared to the Shuttle Radar Topography Mission (SRTM) in terms of vertical accuracy. The results of the experiments reveal that the Copernicus DEM is more accurate than the SRTM. In the Tehran and Jam examples, the root mean square error (RMSE) for Copernicus DEM (30 m) is 5.72 and 2.19 meters, respectively. Also, this value for SRTM is 6.10 and 3.95 respectively.
IMPROVED WATERSHED SEGMENTATION ALGORITHM FOR TREE CROWNS EXTRACTION FROM MULTI-SPECTRAL UAV-BASED AERIAL IMAGES
Authors: Haddadi Amlashi H.
Published: January 2023

Abstract. Due to many problems such as diseases and pests, low fertility, and dehydration, trees need immediate actions to be taken in time of need. Since they are an important source of fruit, food, and nutrients consumed by humans, keeping track of the trees in orchards is a crucial issue in recent years. Today, drones equipped with multispectral cameras are used in precision agriculture, especially for monitoring and controlling trees. For this cause, two citrus orchards in Iran with an area of 9.2 and 2.67 hectares and a resolution of 3.6 and 0.68 cm were selected for the study area. In this study, First, tree extraction was conducted using four algorithms namely Local maxima, Image binarization, valley following, and watershed segmentation, and a proposed method that is based on the improvement of the watershed algorithm. This method achieved an overall accuracy of 87% and 81% in the two study regions which was higher than common methods. Secondly, the effect of the number of spectral bands on the accuracy of tree extraction was investigated. As a result, by adding of Red-Edge and NIR bands, the accuracy increased by about 5% and 7%. Therefore, experts suggested using NIR and Red-Edge bands besides RGB bands.