bluuebunny/crossref_metadata_2025 huggingface dataset:
Influence of persistent thyroxine reduction on spermatogenesis in rats neonatally exposed to 2,2′,4,4′,5,5′‐hexa‐chlorobiphenyl
Authors: Xiao Wusheng , Li Keyong , Wu Qing , Nishimura Noriko , Chang Xiuli , Zhou Zhijun
Published: December 2009

BACKGROUND: The aim of the present study is to determine the long‐term testicular effects of neonatal exposure to PCB153. METHODS: Sprague‐Dawley (SD) rats were treated by oral gavage with PCB153 in corn oil at doses of 0, 0.025, and 2.5 mg/kg per day from postnatal day 3 (PND 3) to PND7. The rats were sacrificed on PND 8 and PND 77. TUNEL in situ detection for testis apoptosis, immunohistochemical staining of thyroid gland for thyroxine (T4), semi‐quantitative RT‐PCR for mRNA expression, and radioimmunoassay (RIA) for serum hormone levels were performed. RESULTS: Neonatal treatment with PCB153 at both doses had no obvious effects on body weight, testis weight, testis histology, and germ cell apoptosis, but decreased T4 staining in thyroid gland was observed on PND 8. On PND 77, neonatal treatment with 2.5 mg/kg per day of PCB153 significantly reduced daily sperm product (DSP). Serum levels of thyroxine (T4) and free thyroxine (FT4) decreased, but there were no differences in thyroid‐stimulating hormone (TSH) level between the control and exposed groups. Gap junction connexin43 (CX43) and cyclin‐dependent kinase inhibitor (CDKI) P27kip1 mRNA expression, which was associated with Sertoli cell differentiation, was significantly reduced after PCB153 treatment on PND 8 but not on PND 77. Androgen‐binding protein (ABP) and androgen receptor (AR) mRNA expression, which indicates Sertoli cell maturation, was suppressed on PND 77 after neonatal PCB153 exposure. CONCLUSIONS: The findings in this study suggest that neonatal exposure to PCB153 induces persistent T4 reduction, which disturbs Sertoli cell function, and subsequently results in alterations in adult spermatogenesis. Birth Defects Res (Part B) 89:18–25, 2010. © 2009 Wiley‐Liss, Inc.
Developmental and reproductive toxicology studies in nonhuman primates
Authors: Chellman Gary J. , Bussiere Jeanine L. , Makori Norbert , Martin Pauline L. , Ooshima Yojiro , Weinbauer Gerhard F.
Published: December 2009

Developmental and reproductive toxicology testing in nonhuman primates (NHPs) has become more common due to the increasing number of biopharmaceuticals in drug development, since NHPs are frequently the only species to express pharmacologic responses similar to humans. NHPs may also be used to help resolve issues associated with small‐molecule reproductive toxicology in traditional species (rodents and rabbits). Adequate designs in NHP are presented for developmental toxicity (embryo‐fetal development, pre‐postnatal development, enhanced pre‐postnatal development), reproductive toxicity (male and female), and juvenile toxicity studies. Optional parameters that may be included in these studies are discussed, as are new study designs that consolidate multiple aspects of the reproductive assessment and thereby conserve the limited supply of sexually mature NHPs available for testing. The details described will assist scientists in pharmaceutical, regulatory, and contract research organizations who are involved in conducting these unique studies to optimize their design based on case‐by‐case considerations. Birth Defects Res (Part B) 86:446–462, 2009. © 2009 Wiley‐Liss, Inc.
An LC/MS method for the quantitative determination of 7α‐OH DHEA and 7β‐OH DHEA: an application for the study of the metabolism of DHEA in rat brain
Authors: Li Aiqun , May Matthew P. , Bigelow James C.
Published: December 2009

Dehydroepiandrosterone (DHEA) is an important neurosteroid with neuronal protection and memory enhancement functions. 7α‐OH DHEA and 7β‐OH DHEA are the two important metabolites of DHEA in the brain. We have developed an LC/MS method to quantitatively analyze 7α‐OH DHEA and 7β‐OH DHEA. Chromatographic separation was carried out on a C18 column with gradient elution using mobile phases of formic acid in acetonitrile and in water formic acid. Mass spectral detection was performed with a ThermoFinnigan LCQ advantage quadruple ion trap mass spectrometer with electrospray ionization. Positive ion chromatograms were acquired using single ion monitoring. The protonated molecule was 305 m/z, but the most abundant ion (269 m/z) was used for quantification. This method was validated and applied to investigate the 7‐hydroxylation of DHEA. When incubating DHEA with rat brain microsomes, both 7α‐OH DHEA and 7β‐OH DHEA were observed, but 7α‐OH DHEA was the major metabolite. Copyright © 2009 John Wiley & Sons, Ltd.
Carotid artery stenting in high surgical risk patients using the FiberNet® embolic protection system: The EPIC trial results
Authors: Myla Subbarao , Bacharach J. Michael , Ansel Gary M. , Dippel Eric J. , McCormick Daniel J. , Popma Jeffrey J.
Published: December 2009

Objective: The multicenter EPIC (FiberNet Embolic Protection System in Carotid Artery Stenting Trial) single‐arm trial evaluated the 30‐day outcomes of a new design concept for embolic protection during carotid artery stenting (CAS). Background: Embolic protection filters available for use during CAS include fixed and over‐the‐wire systems that rely on embolic material capture within a “basket” structure. The FiberNet® Embolic Protection System (EPS), which features a very low crossing profile, consists of a three‐dimensional fiber‐based filter distally mounted on a 0.014 inch guidewire with integrated aspiration during filter retrieval. Methods: The trial enrolled 237 patients from 26 centers. Demographics, clinical and lesion characteristics, as well as adverse events through a 30‐day follow‐up were recorded. The mean age of the patients was 74 years, 64% were male and 20% had symptomatic carotid artery disease. Results: The combined major adverse event (MAE) rate at 30 days for all death, stroke, and myocardial infarction was 3.0%. There were three major strokes (two ischemic and one hemorrhagic) and two minor strokes (both ischemic) for a 2.1% 30‐day stroke rate. The procedural technical success rate was 97.5% and macroscopic evidence of debris was reported in 90.9% of the procedures. Conclusions: The FiberNet EPS, used with commercially available stents, produced low stroke rates following CAS in high surgical risk patients presenting with carotid artery disease. The unique filter design including aspiration during retrieval may have contributed to the low 30‐day stroke rate reported during CAS in patients considered at high risk for complications following carotid endarterectomy (CEA). © 2009 Wiley‐Liss, Inc.
Coil occlusion of a subclavian mycotic aneurysm
Authors: Kische Stephan , Ince Hüseyin , Peuster Matthias
Published: December 2009

We report the first successful application of nonferromagnetic embolization coils for endovascular exclusion of a mycotic right subclavian artery aneurysm. A 58‐year‐old woman presented with acute cervical pain and a pulsatile mass in the right supraclavicular fossa under antibiotic medication for subacute infectious endocarditis. Diagnostic work‐up including duplex sonography, digital subtraction angiography, and magnetic resonance imaging demonstrated a saccular aneurysm of the extrathoracic right subclavian artery. As an alternative to open surgery or stent‐graft repair, this pathology was electively treated by transcatheter coil embolization. No neurological deficit or ischemic symptoms were noted during 9 months clinical follow‐up. Multislice computed tomography scan revealed complete occlusion of the mycotic aneurysm 6 months after the interventional procedure. Transcatheter closure with Inconel embolization coils is a cost‐effective and safe therapeutic option in patients with mycotic aneurysm originating from the subclavian artery. © 2010 Wiley‐Liss, Inc.
Percutaneous transcatheter arterial embolization of inferior pancreatico‐duodenal artery aneurysms associated with celiac artery stenosis or occlusion
Authors: Dave Bhavika , Sharma Ashish , Kwolek Christopher , DeMoya Mark , Wicky Stephan , Kalva Sanjeeva
Published: December 2009

Objectives: To report our experience with percutaneous TAE of true IPDA aneurysms. Background: Most IPDA aneurysms are ruptured at presentation causing a high mortality risk. Minimally invasive treatment approaches may improve overall outcomes in such patients. Methods: Between 1996 and 2007, seven patients (5 Males; mean age 55y) with symptomatic IPDA aneurysms and severe degree (>75%) celiac artery stenosis were treated with percutaneous TAE. The medical and imaging records were reviewed for demographics, clinical presentation, treatment, complications and follow‐up. Patients presented with epigastric pain (7/7), hemodynamic shock (2/7) and rectal bleeding (2/7). Selective catheter angiography was performed in all patients with the intent to embolize the aneurysms. Results: A total of nine aneurysms were seen in seven patients. Two patients had two aneurysms each. The aneurysms ranged in size from 0.5 to 4.0 cm (mean 1.9 cm). Trans‐catheter coil embolization was successful in 8/9 (89%) aneurysms in 6 patients. Following unsuccessful TAE of one aneurysm in one of the patient, the aneurysm was treated successfully with direct CT‐guided percutaneous transabdominal injection of N‐butyl‐2‐cyanoacrylate. There were no complications on follow up. Angioplasty and stenting of the celiac artery were performed in one patient for complete occlusion. None of the patients developed clinical or imaging evidence of visceral ischemia following embolization. None had recurrent symptoms during clinical follow‐up (median 3 years, range 0.5–13.5 years). Follow‐up CT (Median 6.6 months, range 4 days–11.5 years) in all patients showed no recurrence of the aneurysm. Conclusion:IPDA aneurysms associated with celiac axis stenosis can be successfully treated with percutaneous embolization with minimal recurrence. © 2009 Wiley‐Liss, Inc.
Paravalvular regurgitation one year after transcatheter aortic valve implantation
Authors: Rajani Ronak , Kakad Mitesh , Khawaja Muhammed Z. , Lee Lorraine , James Rachael , Saha Mrinal , Hildick‐Smith David
Published: December 2009

Objectives: The aim of this study was to assess the natural history of paravalvular regurgitation at 1 year in patients undergoing TAVI. Background: The immediate incidence of paravalvular regurgitation is estimated to be between 65 and 85% following transcatheter aortic valve implantation (TAVI). There is limited data as to whether this deteriorates during follow‐up. Methods: Forty‐six patients were recruited from a TAVI programme at our institute. All patients underwent an assessment of prosthetic valve function periprocedurally with aortography and immediately postprocedurally with transthoracic echocardiography. Twenty‐one patients with a median age was 83 (66–91) years of whom 14 were male reached 1 year follow‐up, 13 of whom were available for repeat transthoracic echocardiography. Results: The incidence of paravalvular regurgitation immediately following TAVI was 86%. Of them 57% had ≤ mild regurgitation and 29% had > mild regurgitation. At 1 year the incidence of paravalvular regurgitation was 77%. 54% had ≤ mild regurgitation and 34% > mild regurgitation. No patient had severe regurgitation. The degree of regurgitation reduced in 6 (46%), stayed the same in 3 (23%), and increased in 4 (31%) of patients. Conclusions: Patients undergoing TAVI have an immediate postprocedural risk of regurgitation of 86%. In the majority of cases the degree of paravalvular CoreValve® regurgitation is mild, and remains stable in 70% of patients during medium term follow‐up. © 2009 Wiley‐Liss, Inc.
Novel application of the “CART” technique for endovascular treatment of external iliac artery occlusions
Authors: Rogers R. Kevin , Tsai Thomas , Casserly Ivan P.
Published: December 2009

We report the novel application of the Controlled Antegrade and Retrograde subintimal Tracking technique for the endovascular treatment of occlusions of the external iliac artery (EIA). We hypothesized that this technique would limit the extent of subintimal dissection to the length of the EIA occlusion, thus preserving patency of the internal iliac artery proximally and the circumflex iliac artery distally and minimizing the length of stent required to treat the occlusion, including the length of stent placed in the common femoral artery. The technical execution and clinical experience with this technique is reported. © 2009 Wiley‐Liss, Inc.
σ‐Alkylpalladium Intermediates in Intramolecular Heck Reactions:Isolation and Catalytic Activity
Authors: Beccalli Egle M. , Borsini Elena , Brenna Stefano , Galli Simona , Rigamonti Micol , Broggini Gianluigi
Published: December 2009

The isolation of σ‐alkylpalladium Heck intermediates, possible when β‐hydride elimination is inhibited, is a rather rare event. Performing intramolecular Heck reactions on N‐allyl‐2‐halobenzylamines in the presence of [Pd(PPh3)4], we isolated and characterized a series of stable bridged palladacycles containing an iodine or bromine atom on the palladium atom. Indolyl substrates were also tested for isolation of the corresponding complexes. X‐ray crystallographic analysis of one of the indolyl derivatives revealed the presence of a five‐membered palladacycle with the metal center bearing a PPh3 ligand and an iodine atom in a cis position with respect to the nitrogen atom. The stability of the σ‐alkylpalladium complexes is probably a consequence of the strong constraint resulting from the bridged junction that hampers the cisoid conformation essential for β‐hydride elimination. Subsequently, the thus obtained bridged five‐membered palladacycles were proven to be effective precatalysts in Heck reactions as well as in cross‐coupling processes such as Suzuki and Stille reactions.
Direct Growth of Single‐Crystal Pt Nanowires on Sn@CNT Nanocable: 3D Electrodes for Highly Active Electrocatalysts
Authors: Sun Shuhui , Zhang Gaixia , Geng Dongsheng , Chen Yougui , Banis Mohammad Norouzi , Li Ruying , Cai Mei , Sun Xueliang
Published: December 2009

A newly designed and fabricated novel three dimensional (3D) nanocomposite composed of single‐crystal Pt nanowires (PtNW) and a coaxial nanocable support consisting of a tin nanowire and a carbon nanotube (Sn@CNT) is reported. This nanocomposite is fabricated by the synthesis of Sn@CNT nanocables by means of a thermal evaporation method, followed by the direct growth with PtNWs through a facile aqueous solution approach at room temperature. Electrochemical measurements demonstrate that the PtNWSn@CNT 3D electrode exhibits enhanced electrocatalytic performance in oxygen reduction reaction (ORR) for polymer electrolyte membrane fuel cells (PEMFCs), methanol oxidation (MOR) for direct methanol fuel cells (DMFCs), and CO tolerance compared with commercial ETEK Pt/C catalyst made of Pt nanoparticles.
ChemInform Abstract: Crystal Structure and Electron Density in the Apatite‐Type Ionic Conductor La9.71(Si5.81Mg0.18)O26.37.
Authors: Ali Roushown , Yashima Masatomo , Matsushita Yoshitaka , Yoshioka Hideki , Izumi Fujio
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Structural Characterization of the Perovskite Series SrxCa1‐x‐yNdyMnO3: Influence of the Jahn—Teller Effect.
Authors: Kennedy Brendan J. , Saines Paul J. , Ting Jimmy , Zhou Qingdi , Kimpton Justin A.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Giant Dielectric Constant Response of the Composites in Ternary System CuO—TiO2—CaO.
Authors: Veith Michael , Ren Shuhua , Wittmar Matthias , Bolz Henning
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ionic Conductivity, Structure and Oxide Ion Migration Pathway in Fluorite‐Based Bi8La10O27.
Authors: Li Yuandi , Hutchinson Tom P. , Kuang Xiaojun , Slater Peter R. , Johnson Mark R. , Radosavljevic Evans Ivana
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Aromatic Heterocycles as Activating Groups for Asymmetric Conjugate Addition Reactions. Enantioselective Copper‐Catalyzed Reduction of 2‐Alkenylheteroarenes.
Authors: Rupnicki Leszek , Saxena Aakarsh , Lam Hon Wai
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enantioselective α‐Trifluoromethylation of Aldehydes via Photoredox Organocatalysis.
Authors: Nagib David A. , Scott Mark E. , MacMillan David W. C.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Enamide‐Benzyne‐[2 + 2] Cycloaddition: Stereoselective Tandem [2 + 2]—Pericyclic Ring‐Opening—Intramolecular N‐Tethered [4 + 2] Cycloadditions.
Authors: Feltenberger John B. , Hayashi Ryuji , Tang Yu , Babiash Eric S. C. , Hsung Richard P.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A New Reagent for Selective Reduction of Nitro Group.
Authors: Raju B. , Ragul R. , Sivasankar B. N.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Solvent‐Promoted and ‐Controlled Aza‐Michael Reaction with Aromatic Amines.
Authors: De Kavita , Legros Julien , Crousse Benoit , Bonnet‐Delpon Daniele
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Morita—Baylis—Hillman Reactions Between Conjugated Nitroalkenes or Nitrodienes and Carbonyl Compounds.
Authors: Deb Indubhusan , Shanbhag Pramod , Mobin Shaikh M. , Namboothiri Irishi N. N.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Elemental Fluorine. Part 23. Direct Fluorination of β‐Ketoesters as an Approach to Enantioselective Fluorination.
Authors: Chambers Richard D. , Nakano Takashi , Okazoe Takashi , Sandford Graham
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Rhenium‐ and Manganese‐Catalyzed Insertion of Alkynes into a Carbon—Carbon Single Bond of Cyclic and Acyclic 1,3‐Dicarbonyl Compounds.
Authors: Kuninobu Yoichiro , Kawata Atsushi , Nishi Mitsumi , Yudha S. Salprima , Chen Jingjin , Takai Kazuhiko
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ferric Chloride Hexahydrate‐Catalyzed Highly Regio‐ and Stereoselective Conjugate Addition Reaction of 2,3‐Allenoates with Grignard Reagents: An Efficient Synthesis of β,γ‐Alkenoates.
Authors: Chai Guobi , Lu Zhan , Fu Chunling , Ma Shengming
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Direct Intermolecular Cross‐Benzoin Type Reaction: N‐Heterocyclic Carbene‐Catalyzed Coupling of Aromatic Aldehydes with Trifluoromethyl Ketones.
Authors: Enders Dieter , Henseler Alexander
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: H2O2/SOCl2: A Useful Reagent System for the Conversion of Thiocarbonyls to Carbonyl Compounds.
Authors: Bahrami Kiumars , Khodaei Mohammad M. , Farrokhi Azita
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Catechol Violet as New, Efficient, and Versatile Ligand for Cu(I)‐Catalyzed C—S Coupling Reactions.
Authors: Basu Basudeb , Mandal Bablee , Das Sajal , Kundu Sekhar
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Mono‐, Bis‐ and Tris‐piperidine Fused Imidazolinium Salts: Their in situ Catalytic Applications for C—C Bond Formation in Aqueous Solutions
Authors: Tuerkmen Hayati , Can Rahime , Cetinkaya Bekir
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Atom‐Efficient Vinylic Arylations with Triarylbismuths as Substoichiometric Multicoupling Reagents under Palladium Catalysis.
Authors: Rao Maddali L. , Jadhav Deepak N. , Venkatesh Varadhachari
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Expedient One‐Pot Synthesis of Novel 10‐Substituted 9‐Aminophenanthrenes.
Authors: Rochais Christophe , Yougnia Rodrigue , Dallemagne Patrick , Rault Sylvain
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Highly Stereoselective Epoxidation of O‐Protected 3‐Hydroxy‐1‐nitroalkenes.
Authors: Jain Amit , Rodriguez Santiago , Lopez Irakusne , Gonzalez Florenci V.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Nitroketene Dithioacetal Chemistry: Synthesis of 2‐Alkylthio‐3‐nitrothiophenes from Nitroketene Dithioacetate and Chloromethyl Ketones.
Authors: Rao H. Surya Prakash , Vasantham K.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Palladium(II)‐Catalyzed Regioselective Direct C2 Alkenylation of Indoles and Pyrroles Assisted by the N‐(2‐Pyridyl)sulfonyl Protecting Group.
Authors: Garcia‐Rubia Alfonso , Gomez Arrayas Ramon , Carretero Juan C.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A New Approach to Pyrrolocoumarin Derivatives by Palladium‐Catalyzed Reactions: Expedient Construction of Polycyclic Lamellarin Scaffold.
Authors: Chen Lei , Xu Ming‐Hua
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Silver‐Catalyzed Preparation of Oxazolidinones from Carbon Dioxide and Propargylic Amines.
Authors: Yoshida Shunsuke , Fukui Kosuke , Kikuchi Satoshi , Yamada Tohru
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of 2,1‐Benzisoxazoles by Nucleophilic Substitution of Hydrogen in Nitroarenes Activated by the Azole Ring.
Authors: Pokhodylo Nazariy T. , Teslenko Yuriy O. , Matiyuchuk Vasyl S. , Obushak Mykola D.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Iodogen: A Novel Reagent for the Oxidation of Urazoles under Heterogeneous Conditions.
Authors: Khoramabadi‐zad Ahmad , Shiri Azam , Zolfigol Mohammad Ali , Mallakpour Shadpour
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: IBX/TEAB‐Mediated Oxidative Dimerization of Thioamides: Synthesis of 3,5‐Disubstituted 1,2,4‐Thiadiazoles
Authors: Patil Pravin C. , Bhalerao Dinesh S. , Dangate Prasad S. , Akamanchi Krishnacharya G.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Functionalized α‐Pyrone and Butenolide Derivatives by Rhodium‐Catalyzed Oxidative Coupling of Substituted Acrylic Acids with Alkynes and Alkenes.
Authors: Mochida Satoshi , Hirano Koji , Satoh Tetsuya , Miura Masahiro
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Predictable and Regioselective Insertion of Internal Unsymmetrical Alkynes in Rhodium‐Catalyzed Cycloadditions with Alkenyl Isocyanates.
Authors: Friedman Rebecca Keller , Rovis Tomislav
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Efficient Biginelli One‐Pot Synthesis of New Benzoxazole‐Substituted Dihydropyrimidinones and Thiones Catalyzed by Trifluoro Acetic Acid under Solvent‐Free Conditions.
Authors: Shobha D. , Chari M. Adharvana , Ahn K. H.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Design, Synthesis and Anticancer Evaluation of Novel Tetrahydroquinoline Derivatives Containing Sulfonamide Moiety.
Authors: Ghorab Mostafa M. , Ragab Fatma A. , Hamed Mostafa M.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Delaumonones A and B, New Antiplasmodial Quassinoids from Laumoniera bruceadelpha.
Authors: Oshimi Shiori , Takasaki Aki , Hirasawa Yusuke , Hosoya Takahiro , Awang Khalijah , Hadi A. Hamid A. , Ekasari Wiwied , Widyawaruyanti Aty , Morita Hiroshi
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Thiourea‐Tethered C‐Glycosyl Amino Acids via Isothiocyanate—Amine Coupling.
Authors: Barghash Reham F. , Massi Alessandro , Dondoni Alessandro
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Medicinal Flowers. Part 30. Eight New Glycosides, Everlastosides F—M, from the Flowers of Helichrysum arenarium.
Authors: Morikawa Toshio , Wang Li‐Bo , Ninomiya Kiyofumi , Nakamura Seikou , Matsuda Hisashi , Muraoka Osamu , Wu Li‐Jun , Yoshikawa Masayuki
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Lannotinidines H—J, New Lycopodium Alkaloids from Lycopodium annotinum.
Authors: Ishiuchi Kan'ichiro , Kodama Shihomi , Kubota Takaaki , Hayashi Shigeki , Shibata Toshiro , Kobayashi Jun'ichi
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Lignans from the Bark of Zanthoxylum planispinum.
Authors: Yang Guang‐Zhong , Hu Yun , Yang Bo , Chen Yu
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Two New Phenylglycol Derivatives Isolated from Syringa reticulata var. mandshurica and Their Antifungal Activities.
Authors: Xu Qiong Ming , Liu Yan Li , Li Xiao Ran , Feng Yu Lin , Yang Shi Lin
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Toward Efficient Palladium‐Catalyzed Allylic C—H Alkylation.
Authors: Jensen Thomas , Fristrup Peter
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Creating Aldols Differently: How to Build‐Up Aldol Products with Quaternary Stereocenters Starting from Alkynes
Authors: Koester Dennis C. , Werz Daniel B.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Concerted Nucleophilic Substitution Reactions at Vinylic Carbons
Authors: Chiba Shunsuke , Ando Kaori , Narasaka Koichi
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthetic Nitroimidazoles: Biological Activities and Mutagenicity Relationships
Authors: Mital Alka
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Oxidation of DNA and Its Components with Reactive Oxygen Species
Authors: Kuznetsova A. A. , Knorre D. G. , Fedorova O. S.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Anitumor Agents. Part 267. Anti‐AIDS‐Agents. Part 77. Plant‐Derived Triterpenoids and Analogues as Antitumor and anti‐HIV Agents
Authors: Kuo Reen‐Yen , Qian Keduo , Morris‐Natschke Susan L. , Lee Kuo‐Hsiung
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Excited Electronic States and Nonadiabatic Effects in Contemporary Chemical Dynamics
Authors: Mahapatra Susanta
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Characterizing Quinone Methides by Spectral Global Fitting and 13C Labeling
Authors: Skibo Edward B.
Published: December 2009

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Nano‐ice on Boron Nitride Nanomesh: Accessing Proton Disorder
Authors: Ma Haifeng , Brugger Thomas , Berner Simon , Ding Yun , Iannuzzi Marcella , Hutter Jürg , Osterwalder Jürg , Greber Thomas
Published: December 2009

Water was investigated on a h‐BN/Rh(111) nanomesh template using variable temperature scanning tunneling microscopy (STM) and density functional theory (DFT) calculations. Below 52 K, two distinct phases self‐assemble within the 3.2 nm unit cell of the nanomesh that consists of “holes” and “wires”. In the 2 nm holes, an ordered phase of nano‐ice crystals with about 40 molecules is found. The ice crystals arrange in a bilayer honeycomb lattice, where hydrogen atoms of the lower layer point to the substrate. The phase on the 1 nm wires is a low density gas phase. Tunneling barrier height dI/dz spectroscopy measurements reveal the dipoles of individual molecules in the nano‐ice clusters and access proton disorder.
Structural distortions of semiconducting silicon crystals caused by constant electric field
Authors: Aboyan A. O. , Aghbalyan S. G.
Published: December 2009

Structural distortions in nonpolar, particularly, in semiconducting silicon crystals, caused by constant electric field have been disclosed by means of X‐ray interferometry. It was shown that in the field both the direction of moiré fringes and the frequency (period) are changed, and the moiré patterns disappear at values of potential difference in excess of 1.5 kV. The moiré pattern obtained under the action of electrostatic field is independent of the direction (polarity) of the field, the pictures for both the polarities being completely identical. (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Deposition of Niobium Nitride Thin Films from Tert‐Butylamido‐Tris‐(Diethylamido)‐Niobium by a Modified Industrial MOCVD Reactor
Authors: Thiede Tobias B. , Parala Harish , Reuter Knud , Passing Gerd , Kirchmeyer Stephan , Hinz Jörn , Lemberger Martin , Bauer Anton J. , Barreca Davide , Gasparotto Alberto , Fischer Roland A.
Published: December 2009

Niobium nitride thin films are deposited on 2″ silicon (100) wafers using a modified industrial metal‐organic (MO) CVD reactor of the type AIX‐200RF, starting from tert‐butylamido‐tris‐(diethylamido)‐niobium (TBTDEN) and ammonia. Films of thicknesses 50‐200 nm are deposited at temperatures ranging from 400 °C to 800 °C under reactor pressures of 1 and 5 mbar using various ammonia flow rates, and are characterized by the use of complementary techniques, namely X‐ray diffraction (XRD), scanning electron microscopy (SEM), secondary neutral mass spectrometry (SNMS), Rutherford backscattering spectrometry (RBS), X‐ray photoelectron spectroscopy (XPS), and electrical measurements. Films deposited above 450 °C consist of the cubic δ‐NbN phase, apart from the presence of Nb‐O and Nb‐O‐N species predominantly in the outermost film regions. The lowest specific resistivities, determined by four point probe measurements, are in the range 500–600 µΩ cm. A NbN/SiO2/p‐Si gate stack is fabricated using the grown niobium nitride films. From the capacitance‐voltage (C‐V)‐curves, flat‐band voltages are extracted which, when plotted against SiO2‐insulator thickness, yield a work function of 4.72 eV for as‐deposited films.
Synthesis of Fused 4‐Iodoselenophene[2,3‐b]thiophenes by Electrophilic Cyclization of 3‐Alkynylthiophenes
Authors: Stein André L. , da Rocha Juliana , Menezes Paulo Henrique , Zeni Gilson
Published: December 2009

We present here our results on the electrophilic cyclization reaction of 3‐alkynylthiophenes with different electrophiles such as I2, ICl, and PhSeBr. The cyclization reaction proceeded cleanly under mild reaction conditions, giving fused 4‐iodoselenophene[2,3‐b]thiophenes in excellent yields. In addition, the obtained chalcogenophenes were readily transformed into more complex products through palladium‐ or copper‐catalyzed cross‐coupling reactions with thiols, boronic acids, and organozinc reagents.
Reduction of Alkynyl α‐Hydroxy Esters: Stereoselective α‐Ketol Rearrangement
Authors: Hameury Thomas , Bellosta Véronique , Guillemont Jérôme , Van Hijfte Luc , Cossy Janine
Published: December 2009

The α‐ketol rearrangement of tertiary α‐hydroxy esters induced by LiAlH4/acid treatment provides α‐hydroxy ketones in good yields and high diastereoselectivity. A mechanism is proposed for this reaction as well as a model to explain the diastereoselectivity of the rearrangement.
Aminal–Pyrrolidine Organocatalysts – Highly Efficient and Modular Catalysts for α‐Functionalization of Carbonyl Compounds
Authors: Quintard Adrien , Belot Sébastien , Marchal Estelle , Alexakis Alexandre
Published: December 2009

The substitution of the 4‐position of hydroxyproline by aphenol group, together with an aminal on the 2‐position, gave a synergistic effect leading to two powerful complementary organocatalysts. They show excellent enantiocontrol in the α‐functionalization of a wide range of linear/branched aldehydes and ketones, including Michael additions to ethenediyl disulfones or nitrostyrene and α‐amination. We obtained ees up to 98.5 % with low catalyst loadings (down to 1 mol‐%). As a proof of efficiency, TOFs of up to 1000 h–1 could be obtained.
A framework for the development of STR genotyping in domestic animal species: Characterization and population study of 12 canine X‐chromosome loci
Authors: van Asch Barbara , Pinheiro Raquel , Pereira Rui , Alves Cíntia , Pereira Vânia , Pereira Filipe , Gusmão Leonor , Amorim António
Published: December 2009

This study reports the methodology used to search, select and characterize STR loci on the canine X chromosome using publicly available genome resources and following the current guidelines for human and non‐human forensic testing. After several rounds of selection, 12 X‐STR markers were optimized for simultaneous co‐amplification in a single PCR, and genetic profiles were determined in a sample of 103 unrelated dogs. Mendelian inheritance was verified and mutation rates were assessed using family groups. Alleles that varied in size were sequenced to create a standardized nomenclature proposal based on the number of repeats. All loci conformed to Hardy–Weinberg expectations. The resulting panel showed high forensic efficiency, presenting high values of power of discrimination (in males and females) and mean exclusion chance, both in trios involving female offspring and in duos composed of dam and male offspring. Its use may complement the information obtained by autosomal STR analysis and contribute to the resolution of complex cases of kinship in dogs. The presented methodology for the de novo construction of an STR multiplex may also provide a helpful framework for analogous work in other animal species. As an increasing number of reference genomes become available, convenient tools for individual identification and parentage testing based on STR loci selected from autosomes or sex chromosomes' sequences may be created following this strategy.
Large‐fruited Salicaceae s.l. from the Miocene tuff of the Eichelskopf, northern Hessen, Germany
Authors: Manchester S. R. , Hottenrott M.
Published: December 2009

Reexamination of Saccoglottis kayseri (Schindehütte) Kirchheimer from the Miocene tuff of the Eichelskopf southeast of Homberg an der Efze in northern Hessen, Germany, indicates that the species was incorrectly attributed to Humiriaceae. The large ovoid fruits are 6‐ and 7‐valved capsules bearing numerous seeds in parietal position. The outer surface is hexagonally or heptagonally ridged. Each valve of the capsule bears a broad, ventral longitudinal band that is densely punctate indicating the position of numerous seeds. These characters point to affinities with the Salicaceae s.l. (incl. most former Flacourtiaceae), and match particularly well with Itoa L., which is distributed today in southern China and eastern Malesia. However, the fruit valves appear to separate only from the apical end, rather than both from base and apex which is a feature of fruits in the Itoa‐Carrierea‐Poliothyrsis group. We treat the fruits as a new genus of Salicaceae, Schindehuettea gen. nov. under the binomial Schindehuettea kayseri (Schindehütte) Manchester. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Pollen morphology of Alcea L. and Althaea L. genera (Malvaceae) in Turkey
Authors: Cabi E. , Başer B. , Uzunhisarcikli M. E. , Yavru A.
Published: December 2009

Pollen grains of 22 taxa from Alcea L. and Althaea L. genera (Malvaceae) were examined using light microscope and scanning electron microscope to assess whether pollen traits can be used to delimitate at generic and specific levels. Furthermore quantitative data were subjected to cluster analysis. The pollen grains of Althaea genus are spheroidal, pantoporate, echinate which is characterized by having subglobose pattern at the base of echinae. The pollen of Alcea are spheroidal, pantoporate, echinate and baculate. Distances between pori are longer in Althaea (9.04–12.75 μm) pollens than pollens of Alcea (5.12–7.28 μm). The results of this study confirmed that differences about pollen characteristics among the taxa are not functional in separating taxa at specific level especially in Alcea genus, whereas there have been clear differences based on pollen morphology between two closely related genera. (© 2009 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)