bluuebunny/crossref_metadata_2025 huggingface dataset:
Synthesis of Vinyl‐Substituted β‐Diketones for Polymerizable Metal Complexes.
Authors: Southard Glen E. , Murray George M.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of 1‐Aryl‐tetralins and 4‐Aryl‐benzopyrans by Sulfoxide‐Mediated Benzylic Carbocation Cyclizations.
Authors: Volonterio Alessandro , Zanda Matteo
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Rhodium(I) Catalyzed Four‐Component Reaction of Fischer Alkenyl Carbene Complexes and 1,1‐Diphenylallene.
Authors: Barluenga Jose , Vicente Ruben , Lopez Luis A. , Tomas Miguel
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Fused Polycyclic Aromatics by Palladium‐Catalyzed Annulation of Arynes Using 2‐Halobiaryls.
Authors: Liu Zhijian , Zhang Xiaoxia , Larock Richard C.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Novel and Highly Efficient Asymmetric Synthesis of Epoxides via Chiral Telluronium Ylides.
Authors: Ou Wen‐Hua , Huang Zhi‐Zhen
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Reaction of 2H‐Azirine Phosphine Oxide and ‐Phosphonates with Nucleophiles. Stereoselective Synthesis of Functionalized Aziridines and α‐ and β‐Aminophosphorus Derivatives.
Authors: Palacios Francisco , Ocha de Retana Ana M. , Alonso Jose M.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Facile Synthesis of Highly Substituted 3‐Aminofurans from Thiazolium Salts, Aldehydes, and Dimethyl Acetylenedicarboxylate.
Authors: Ma Cheng , Ding Hanfeng , Wu Guangming , Yang Yewei
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Open‐Chain Dithioacetals from Thiophene‐2‐carbaldehyde and Its Analogues.
Authors: Papernaya L. K. , Levanova E. P. , Sukhomazova E. N. , Albanov A. I. , Deryagina E. N.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
β,β‐Dinitrostyrenes Reacted with Pyrrole.
Authors: Sheremet E. A. , Trukhin E. V. , Skobeleva A. V. , Berestovitskaya V. M.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Discovery of Novel 1‐Arylmethyl Pyrrolidin‐2‐yl Ethanol Amines as Calcium‐Sensing Receptor Antagonists.
Authors: Gavai Ashvinikumar V. , et al. et al.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Efficient Synthesis of Bis(indolyl)methanes Catalyzed by TiCl4.
Authors: Reddy Y. Thirupathi , Reddy P. Narsimha , Kumar B. Sunil , Rajitha B.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Three‐Component Indole Synthesis Using ortho‐Dihaloarenes.
Authors: Kaspar Ludwig T. , Ackermann Lutz
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Straightforward Synthesis of Di‐, Tri‐ and Tetracyclic Lactams via Catalytic Pauson—Khand and Alder—Ene Reactions of MCR Products.
Authors: Struebing Dirk , Neumann Helfried , Huebner Sandra , Klaus Stefan , Beller Matthias
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Palladium(0)‐Catalyzed Tandem Cyclization of Allenenes: Direct Construction of Tricyclic Heterocycles Through Aromatic C—H Activation.
Authors: Ohno Hiroaki , Miyamura Kumiko , Mizutani Tsuyoshi , Kadoh Yoichi , Takeoka Yusuke , Hamaguchi Hisao , Tanaka Tetsuaki
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Syntheses Based on 4‐Chloro‐1‐[3,5‐di(trifluoromethyl)phenyl]‐, (IIIa) 4‐Chloro‐1‐(2,4‐difluorophenyl)‐5‐formyl‐3‐methyl‐6,7,dihydroindazoles (IIIb), and 4‐Chloro‐5‐formyl‐3‐methyl‐1‐(2‐pyridyl)‐6,7‐dihydroindazoles (XIII).
Authors: Strakova I. , Strakovs A. , Petrova M.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Convenient Oxazole C‐2 Protecting Group: The Synthesis of 4‐ and 5‐Substituted Oxazoles via Metalation of 2‐Triisopropylsilyloxazoles.
Authors: Miller Ross A. , Smith Randi M. , Marcune Benjamin
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Asymmetric Michael Addition Using N‐Cinnamoyl‐ and N‐Crotonyl‐trans‐hexahydrobenzoxazolidin‐2‐ones.
Authors: Perez Lydia , Bernes Sylvain , Quintero Leticia , Anaya de Parrodi Cecilia
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Chemical and Biochemical Transformations of 5‐Ethoxycarbonyl‐5‐phenyl‐2‐isoxazolines.
Authors: Zadrozna Irmina , Kurkowska Joanna , Kruszewska Hanna
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Stereoselective Synthesis of Alkyl Z‐2‐(2‐Amino‐4‐oxo‐1,3‐thiazol‐5(4H)‐yliden)acetates in Solventless Conditions.
Authors: Ramazani Ali , Kazemizadeh Ali Reza , Ganjeie Bijan , Ahmadi Ebrahim
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Asymmetric Synthesis of 1,3‐Thiazolidine‐Derived Spiro‐β‐lactams via a Staudinger Reaction Between Chiral Ketenes and Imines.
Authors: Cremonesi Giuseppe , Dalla Croce Piero , Fontana Francesco , Forni Alessandra , La Rosa Concetta
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of 3‐Aryl‐5‐decapentyl‐1,2,4‐oxadiazoles Possessing Antiinflammatory and Antitumor Properties.
Authors: Bezerra Natercia M. Miranda , De Oliveira Shalom P. , Srivastava Rajendra M. , Da Silva Joel R.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Biological Synthesis of Polyketides from 6‐n‐Pentyl‐α‐pyrone by Streptomyces sp.
Authors: Li Xifeng , Kim Se‐Kwon , Jung Jee H. , Kang Jung Sook , Choi Hong Dae , Son Byeng Wha
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Preyssler Acid: A Mild and Efficient Catalyst for the Protection Alcohols with Dihydropyran.
Authors: Feizi N. , Hassani H. , Hakimi M.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Some Antimicrobial Heterocycles from Pyranotetrahydrocarbazole.
Authors: Mulwad Vinata V. , Patil Chetan A.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ceric Ammonium Nitrate Catalyzed Efficient and Chemoselective Method for Protection and Deprotection of 4‐Oxo‐4H‐1‐benzopyran‐3‐carbaldehydes.
Authors: Shindalkar S. S. , Madje B. R. , Hangarge R. V. , Shingare M. S.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Domino Allylation and Cyclization of ortho‐Alkynylbenzaldehydes with Allyltrimethylsilane Catalyzed by Pd(II)—Cu(II) Bimetallic Systems.
Authors: Asao Naoki , Chan Ching Siew , Takahashi Kumiko , Yamamoto Yoshinori
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
An Oxidatively Releasable Caging Group that Senses Lipid Peroxidation.
Authors: Trumbull Kari A. , Branchaud Bruce P.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Antihypertensive Activity of New 1,4‐Dihydropyridines.
Authors: Hadizadeh Farzin , Fatehi‐Hassanabad Zahra , Bamshad Mohammad , Poorsoghat Hamed , Fatehi‐Hassanabad Mohammad
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Antimalarial Activity of Baylis—Hillman Adducts from Substituted 2‐Chloronicotinaldehydes.
Authors: Narender P. , Srinivas U. , Gangadasu B. , Biswas Sukla , Rao V. Jayathirtha
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
One‐Pot, Three‐Component Synthesis of Dialkyl 1,2‐Dihydroquinoline‐2,3‐dicarboxylates from Triphenylphosphine, Acetylenic Esters, and Amide Derivatives of 2‐Aminobenzaldehyde in Aqueous Acetone
Authors: Ramazani Ali , Ahmadi Ebrahim , Kazemizadeh Ali Reza , Dolatyari Leila , Noshiranzadeh Nader , Eskandari Issa , Souldozi Ali
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
2‐(Adamantan‐1‐yl)imidazo[1,2‐a]pyridines and Their Derivatives.
Authors: Yurchenko R. I. , Ponomarenko A. D. , Svarovskaya N. N. , Tolmachev A. A.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
New Multi‐Component Reaction Accessing 3‐Aminoimidazo[1,2‐a]pyridines.
Authors: Schwerkoske John , Masquelin Thierry , Perun Tom , Hulme Christopher
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Cyclohexyl‐Linked Tricyclic Isoxazoles are Potent and Selective Modulators of the Multidrug Resistance Protein (MRP1).
Authors: Norman Bryan H. , et al. et al.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
N‐8‐Substituted Benztropinamine Analogues as Selective Dopamine Transporter Ligands.
Authors: Grundt Peter , Kopajtic Theresa A. , Katz Jonathan L. , Newman Amy Hauck
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Monoamine Transporter Affinity of 3‐Aryl Substituted Trop‐2‐enes.
Authors: Krunic Aleksej , Mariappan S. V. Santhana , Reith Marteen E. A. , Dunn William J. III
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Diastereocontrolled Synthesis of 6‐Hydroxy‐1,3‐dimethyl‐5‐ (R*,R*‐4‐phenyl‐1,2,3,4‐tetrahydro‐1H‐β‐carbolin‐1‐yl) ‐1H‐pyrimidine‐2,4‐dione.
Authors: Semenov B. B. , Novikov K. A. , Krasnov K. A. , Kachala V. V.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Preparation of Pyrimidine Derivatives as Potential Medicinal Agents by the Reaction of 2‐Amino‐4‐chloro‐6‐methylpyrimidine with Primary and Secondary Amines
Authors: Becker Irwin
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Fluorine‐Containing Heterocycles. Part 12. Fluorine‐Containing Quinazolin‐4‐ones and Azolo[a]quinazolinone Derivatives.
Authors: Lipunova G. N. , Nosova E. V. , Laeva A. A. , Kodess M. I. , Charushin V. N.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Behavior of Dimethylaminonaphthalenes in the Vilsmeier—Haack Reaction.
Authors: Semenova O. N. , Kudryavtseva Yu. A. , Ermolenko I. G. , Patsenker L. D.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Original Synthesis of Oxiranes via TDAE Methodology: Reaction of 2,2‐Dibromomethylquinoxaline with Aromatic Aldehydes.
Authors: Montana Marc , Terme Thierry , Vanelle Patrice
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and SAR of Highly Potent Dual 5‐HT1A and 5‐HT1B Antagonists as Potential Antidepressant Drugs.
Authors: Kling Andreas , et al. et al.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Five‐Membered 2,3‐Dioxo Heterocycles. Part 50. Synthesis and Thermolysis of 3‐Aroyl‐ and 3‐Hetaroyl‐5‐phenyl‐1,2,4,5‐tetrahydropyrrolo [1,2‐a]quinoxalin‐1,2,4‐triones.
Authors: Bozdyreva K. S. , Smirnova I. V. , Maslivets A. N.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Novel “Protecting Group‐Dependent” Alkylation—RCM Strategy to Medium‐Sized Oxacycles: First Total Synthesis of (‐)‐Isoprelaurefucin.
Authors: Lee Hyunjoo , Kim Hyoungsu , Yoon Taehyun , Kim Byungsook , Kim Sanghee , Kim Hee‐Doo , Kim Deukjoon
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis and Stereochemistry of 1H,5H‐Naphtho[1,8‐ef][1,3]dithiocine 2‐Oxides.
Authors: Kikilo P. A. , Khairutdinov B. I. , Shtyrlin Yu. G. , Klochkov V. V. , Klimovitskii E. N.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Pyrimido‐oxazepine as a Versatile Template for the Development of Inhibitors of Specific Kinases.
Authors: Liu Hu , et al. et al.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
An Efficient Strategy for the Synthesis of 1‐Chloroethyl Phosphates and Phosphoramidates.
Authors: Kumpulainen Hanna , Jaervinen Tomi , Saari Raimo , Lehtonen Marko , Vepsaelaeinen Jouko
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Efficient Synthesis of Chiral β‐Seleno Amides via Ring‐Opening Reaction of 2‐Oxazolines and Their Application in the Palladium‐Catalyzed Asymmetric Allylic Alkylation.
Authors: Braga Antonio L. , Vargas Fabricio , Sehnem Jasquer A. , Braga Rodolpho C.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
One‐Pot Stereoselective Synthesis of Alkyl Z‐2‐[2‐Amino‐4‐oxo‐1,3‐selenazol‐5(4H)‐yliden] Acetates.
Authors: Ramazani Ali , Morsali Ali , Ganjeie Bijan , Kazemizadeh Ali Reza , Ahmadi Ebrahim
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Functionalized Diaryldimethylstannanes from the Me2Sn2‐ Dianion by SRN1 Reactions.
Authors: Uberman Paula M. , Martin Sandra E. , Rossi Roberto A.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Studies Toward the Total Synthesis of Vinigrol (I): Synthesis of the Octalin Ring.
Authors: Morency Louis , Barriault Louis
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Seven New Sesquiterpene Lactones from Eupatorium chinense
Authors: Yang Sheng‐Ping , Cheng Jia‐Gao , Huo Jun , Jiang Hua‐Liang , Chen Kai‐Xian , Yue Jian‐Min
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
From Solution Phase to “On‐Column” Chemistry: Trichloroacetimidate‐Based Glycosylation Promoted by Perchloric Acid—Silica.
Authors: Mukhopadhyay Balaram , Maurer Sarah V. , Rudolph Nadine , van Well Renate M. , Russell David A. , Field Robert A.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Enantioselective Total Syntheses of Welwitindolinone A (I) and Fischerindoles I (II) and G (III).
Authors: Baran Phil S. , Richter Jeremy M.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Total Synthesis of (‐)‐Crambidine (I) and Definition of the Relative Configuration of Its Unique Tetracyclic Guanidinium Core.
Authors: Overman Larry E. , Rhee Young Ho
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
An Expeditious Total Synthesis of (.+‐.)‐Stenine.
Authors: Zeng Yibin , Aube Jeffrey
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Bromination of tert‐Butyl Esters of 7α‐Chloro and 7‐Alkylidenedeacetoxycephalosporanic Acid Sulfones.
Authors: Vorona M. , Veinberg G. , Turovskis I. , Lukevics E.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Total Synthesis of CRM646‐A (Ia) and ‐B (Ib), Two Fungal Glucuronides with Potent Heparinase Inhibition Activities.
Authors: Wang Ping , Zhang Zhaojun , Yu Biao
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Antioxidant and Cytotoxic Activities of Xanthones from Cudrania tricuspidata.
Authors: Lee Byong Won , Lee Jin Hwan , Lee Sung‐Tae , Lee Hyun Sun , Lee Woo Song , Jeong Tae‐Sook , Park Ki Hun
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
FR177391, a New anti‐Hyperlipidemic Agent from Serratia. Part 3. Microbial Conversion of FR177391 and Synthesis of FR177391 Derivatives for Its Target Protein Screening by Chemical Genetic Approaches.
Authors: Kobayashi Motoo , Sato Kentaro , Yoshimura Seiji , Yamaoka Makiko , Takase Shigehiro , Ohkubo Mitsuru , Fujii Takashi , Nakajima Hidenori
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A Highly Sensitive Oxygen Sensor Operating at Room Temperature Based on Platinum‐Doped In2O3 Nanocrystals.
Authors: Neri Giovanni , Bonavita Anna , Micali Giuseppe , Rizzo Giuseppe , Galvagno Signorino , Niederberger Markus , Pinna Nicola
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
All‐Electrochemical Synthesis of Submicrometer Cu Structures on Electrochemically Machined p‐Si Substrates.
Authors: Trimmer Andrew L. , Maurer Joseph J. , Schuster Rolf , Zangari Giovanni , Hudson John L.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Novel Triazole Based Inhibitors of Ras Farnesyl Transferase.
Authors: Saha Ashis K. , Liu Li , Simoneaux Richard , DeCorte Bart , Meyer Christophe , Skrzat Stacy , Breslin Henry J. , Kukla Michael J. , End Dave W.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Sulfonamide Chalcone as a New Class of α‐Glucosidase Inhibitors.
Authors: Seo Woo Duck , Kim Jin Hyo , Kang Jae Eun , Ryu Hyung Won , Curtis‐Long Marcus J. , Lee Hyun Sun , Yang Min Suk , Park Ki Hun
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Semiconductor Physics. Dark Spins Come to Light
Authors: Kennedy Thomas
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
What Makes a Single Molecule Magnet?
Authors: Madhu N. T. , Tang Jin‐Kui , Hewitt Ian J. , Clerac Rodolphe , Wernsdorfer Wolfgang , van Slageren Joris , Anson Christopher E. , Powell Annie K.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Single‐Molecule Magnets: A Molecular Approach to Nanoscale Magnetic Materials
Authors: Christou George
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
First Order Magneto‐Structural Phase Transition in Various Functional Materials
Authors: Roy S. B. , Chaddah P.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Spin Gap Antiferromagnets. Materials and Phenomena
Authors: Bose Indrani
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Gas Response Control Through Structural and Chemical Modification of Metal Oxide Films: State of the Art and Approaches
Authors: Korotcenkov G.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Optical Physics of Materials
Authors: Collins Robert W. , Ferlauto Andre S.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Self‐Assembly and Generation of Complexity
Authors: Hosseini Mir Wais
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Sources, Fate and Transport of Perfluorocarboxylates
Authors: Prevedouros Konstantinos , Cousins Ian T. , Buck Robert C. , Korzeniowski Stephen H.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Carbohydrates as Polyfunctional Scaffolds in Combinatorial Synthesis
Authors: Ohnsmann Janina , Madalinski Maciej , Kunz Horst
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthetic Strategies Towards O6‐Substituted Guanine Derivatives and Their Application in Medicine
Authors: Schirrmacher R. , Schirrmacher E. , Muehlhausen U. , Kaina B. , Waengler B.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Ten Years of Research on NOBIN Chemistry
Authors: Ding Kuiling , Li Xin , Ji Baoming , Guo Hongchao , Kitamura Masato
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Photochemical Aspects of Thiocarbonyl Compounds in the Solid‐State
Authors: Sakamoto Masami
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Stereoselective Allylation Reactions of Imines and Related Compounds
Authors: Merino P. , Tejero T. , Delso J. I. , Mannucci V.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Screening of Combinatorial Peptide Libraries for Nanocluster Synthesis
Authors: Slocik Joseph M. , Wright David W.
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Simple Models for Hydrophobic Hydration
Authors: Hoefinger Siegfried , Zerbetto Francesco
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The Chemical Biology that Controls DNA Function and Structure
Authors: Bando Toshikazu , Sugiyama Hiroshi
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Topology and Spin Alignment Utilizing the Excited Molecular Field in π‐Conjugated Organic Spin Systems
Authors: Teki Yoshio
Published: February 2006

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Electron Traps on Oxide Surfaces: (H+)(e−) Pairs Stabilized on the Surface of 17O Enriched CaO
Authors: Chiesa Mario , Paganini Maria Cristina , Giamello Elio , Di Valentin Cristiana , Pacchioni Gianfranco
Published: February 2006

(H+)(e−) pairs generated at the surface of polycrystalline CaO are analyzed for the first time in terms of the interaction of the unpaired electron spin with the nuclear spin of the 17O anions of the surface. CaO crystals enriched in the 17O isotope are prepared and the corresponding hyperfine coupling constants are measured in electron paramagentic resonance (EPR) spectra. The results are analyzed on the basis of cluster model density functional theory calculations. The computed hyperfine coupling constants for (H+)(e−) pairs formed on the edge, corner, and reverse corner sites of the CaO surface allow a tentative assignment of two observed spectral features to specific morphological surface sites.
High density lipoprotein modulates platelet function
Authors: Barlage Stefan , Boettcher Dorothee , Boettcher Alfred , Dada Ashraf , Schmitz Gerd
Published: February 2006

Background

Platelet activation by atherogenic lipoproteins can be antagonized by high density lipoprotein (HDL), probably via interaction with the ATP‐binding cassette transporter A1 (ABCA1).

Methods

ABCA1 expression and its association with cholesterol rich membrane domains was analyzed by mRNA and Western blot analysis. HDL effects on platelet receptor clustering were analyzed by flow cytometric analysis of fluorescence resonance energy transfer between fluorochrome‐labeled antibodies.

Results

ABCA1 expression increased upon megakaryocytic differentiation of human stem cells and ABCA1 protein partially associated to LubroIWX‐resistant membrane domains. Plasma HDL‐cholesterol in healthy donors negatively correlated to the platelet membrane cholesterol content. Receptor cluster analysis revealed a decrease in the association of Gplb and FcγRII upon incubation of platelets with HDL3.

Conclusion

Our results suggest that HDL modulates platelet reactivity by altering lipid raft associated receptor clustering. © 2006 International Society for Analytical Cytology
Automated four‐color analysis of leukocytes by scanning fluorescence microscopy using quantum dots
Authors: Bocsi József , Lenz Dominik , Mittag Anja , Varga Viktor Sebestyén , Molnar Béla , Tulassay Zsolt , Sack Ulrich , Tárnok Attila
Published: February 2006

Background

Scanning fluorescence microscope (SFM) is a new technique for automated motorized microscopes to measure multiple fluorochrome labeled cells (Bocsi et al., Cytometry A 2004, 61:1–8).

Aims

We developed a four‐color staining protocol (DNA, CD3, CD4, and CD8) for the lymphocyte phenotyping by SFM.

Methods

Organic (Alexa488, FITC, PE‐Alexa610, CyChrom, APC) and inorganic (quantum dot (QD) 605 or 655) fluorochromes were used and compared in different combinations. Measurements were performed in suspension by flow cytometer (FCM) and on slide by SFM.

Results

Both QDs were detectable by the appropriate Axioplan‐2 and FCM filters and the AxioCam BW‐camera. CD4/CD8 ratios were highly correlated (P = 0.01) between the SFM and FCM.

Conclusion

Automated SFM is an applicable tool for CD4/CD8 ratio determination in peripheral blood samples with QDs. © 2006 International Society for Analytical Cytology
Bridging biological scales by state–space analysis and modeling using molecular, tissue cytometric and physiological data
Authors: Kriete Andres
Published: February 2006

Combining data streams across different levels of biological organization such as molecular, cellular, and physiological responses support to a system‐wide view in biology. Recently, an unbiased analysis of tissues that provides data‐rich descriptors of tissue architecture, cell types, and cell states has become available. As tissues are centrally located in the biological hierarchy, these advancements give rise to a new class of state variables that are critical to elucidate both underlying cellular, molecular and emergent physiological properties. Concepts to statistically identify, correlate, and model relationships across scales are introduced, which rely on a state–space matrix derived by multi‐omics data aggregation. © 2006 International Society for Analytical Cytology.
E‐LDL and Ox‐LDL differentially regulate ceramide and cholesterol raft microdomains in human Macrophages
Authors: Grandl Margot , Bared Salim Maa , Liebisch Gerhard , Werner Tobias , Barlage Stefan , Schmitz Gerd
Published: February 2006

Atherosclerosis is characterized by the generation of lipid‐loaded macrophage‐derived foam cells. To study the effect of different types of atherogenic lipoproteins, human macrophages were loaded with enzymatically degraded low density lipoprotein (E‐LDL) or oxidized LDL (Ox‐LDL). Cellular cholesterol content was increased by E‐LDL, whereas Ox‐LDL increased the ceramide content. Cell surface expression analysis by flow cytometry and confocal microscopy revealed that Ox‐LDL increased ceramide and lactosylceramide expression compared to E‐LDL loading and induced ceramide rafts, whereas loading with E‐LDL induced cholesterol‐rich microdomains. Formation of different rafts may have consequences for raft associated signaling in cholesterol homeostasis and apoptosis in human macrophages. © 2006 International Society for Analytical Cytology
Identification of naturally processed peptides bound to the class I MHC molecule H‐2Kd of normal and TAP‐deficient cells
Authors: Suri Anish , Walters James J. , Levisetti Matteo G. , Gross Michael L. , Unanue Emil R.
Published: February 2006

This report details the biochemical features of natural peptides selected by the H‐2Kd class I MHC molecule. In normal cell lines, the length of the naturally processed peptides ranged from 8 to 18 amino acids, although the majority were 9‐mers (16% were longer than nine residues). The binding motif for the 9‐mer peptides was dominated by the presence of a tyrosine at P2 and an isoleucine/leucine at the P9 position. The P2 residue contributed most towards binding; and the short peptides bound better and formed longer‐lived cell surface complexes than the long peptides, which bound poorly and dissociated rapidly. The longer peptides did not exhibit this strictly defined motif. Trimming the long peptides to their shorter forms did not enhance binding and conversely, extending the 9‐mer peptides did not decrease binding. The long peptides were present on the cell‐surface bound to H‐2Kd (Kd) and were not intermediate products of the class I MHC processing pathway. Finally, in two different TAP‐deficient cells the long peptides were the dominant species, which suggested that TAP‐independent pathways selected for long peptides by class I MHC molecules.
α‐melanocyte‐stimulating hormone down‐regulates CXC receptors through activation of neutrophil elastase
Authors: Manna Sunil K. , Sarkar Abira , Sreenivasan Yashin
Published: February 2006

Considering the role of interleukin‐8 (IL‐8) in a large number of acute and chronic inflammatory diseases, the regulation of IL‐8‐mediated biological responses is important. Alpha‐melanocyte‐stimulating hormone (α‐MSH), a tridecapeptide, inhibits most forms of inflammation by an unknown mechanism. In the present study, we have found that α‐MSH interacts predominantly with melanocortin‐1 receptors and inhibits several IL‐8‐induced biological responses in macrophages and neutrophils. It down‐regulated receptors for IL‐8 but not for TNF, IL‐4, IL‐13 or TNF‐related apoptosis‐inducing ligand (TRAIL) in neutrophils. It down‐regulated CXCR type 1 and 2 but not mRNA levels. α‐MSH did not inhibit IL‐8 binding in purified cell membrane or affinity‐purified CXCR. IL‐8 or anti‐CXCR Ab protected against α‐MSH‐mediated inhibition of IL‐8 binding. The level of neutrophil elastase, a specific serine protease, but not cathepsin G or proteinase 3 increased in α‐MSH‐treated cells, and restoration of CXCR by specific neutrophil elastase or serine protease inhibitors indicates the involvement of elastase in α‐MSH‐induced down‐regulation of CXCR. These studies suggest that α‐MSH inhibits IL‐8‐mediated biological responses by down‐regulating CXCR through induction of serine protease and that α‐MSH acts as a potent immunomodulator in neutrophil‐driven inflammatory distress.
Epstein‐Barr virus (EBV) latent membrane protein‐1‐specific cytotoxic T lymphocytes targeting EBV‐carrying natural killer cell malignancies
Authors: Demachi‐Okamura Ayako , Ito Yoshinori , Akatsuka Yoshiki , Tsujimura Kunio , Morishima Yasuo , Takahashi Toshitada , Kuzushima Kiyotaka
Published: February 2006

Epstein‐Barr virus (EBV)‐encoded latent membrane protein (LMP) 1 is a potential target for immunotherapy of some proportion of Hodgkin's disease cases, nasopharyngeal carcinomas, EBV‐associated natural killer (NK)/T lymphomas, and chronic active EBV infection (CAEBV). Since it is unknown whether EBV‐infected NK/T cells are susceptible to lysis by LMP1‐specific cytotoxic T lymphohcytes (CTL), we here tested the ability of mRNA‐transduced antigen‐presenting cells (APC) to stimulate rare LMP1‐specific CTL. A 43‐amino acid N‐terminal deletion mutant LMP1 (ΔLMP1) could be efficiently expressed in dendritic cells and CD40‐activated B cells upon mRNA electroporation. ΔLMP1‐expressing APC were found to stimulate LMP1‐specific CTL from a healthy donor and a CTL clone recognized a peptide, IIIILIIFI, presented by HLA‐A*0206 molecules. Processing and presentation of the antigenic peptide proved dependent on expression of an immunoproteasome subunit, low‐molecular‐weight protein‐7, as confirmed by RNA interference gene silencing. Furthermore, an EBV‐infected NK cell line derived from a patient with CAEBV, and another from an NK lymphoma with enforced HLA‐A*0206 expression, were specifically lysed by the CTL. Overall, these data suggest that immunotherapy targeting LMP1 in EBV‐associated NK lymphomas and CAEBV might serve as an alternative treatment modality.
Suppressive effect of alkyl ferulate on the oxidation of microencapsulated linoleic acid
Authors: Fang Xu , Kikuchi Sho , Shima Motohiro , Kadata Megumi , Tsuno Takuo , Adachi Shuji
Published: February 2006

The oxidation processes of linoleic acid mixed with ferulic acid or the 1‐pentyl, 1‐hexyl and 1‐heptyl ferulates, encapsulated with gum arabic or maltodextrin, were studied. The alkyl ferulates had a higher antioxidative effect than ferulic acid, but there was no significant difference among the three alkyl ferulates. Suppression of the oxidation by 1‐hexyl ferulate or ferulic acid was more effective at the higher molar ratios of the additive to linoleic acid. The processes were analyzed using the Weibull equation to evaluate the rate constant, k, and the shape constant, n. Although the k values for linoleic acid encapsulated with gum arabic were lower than that with maltodextrin, the suppressive effect of the alkyl ferulates was more remarkable for linoleic acid encapsulated with maltodextrin than with gum arabic because of the non‐antioxidative ability of maltodextrin. Because the partition coefficient of the alkyl ferulates was much greater than that of ferulic acid, most of the alkyl ferulates would be located in the linoleic acid phase of the microcapsules and effectively suppress the oxidation of linoleic acid.
Effect of filtration on virgin olive oil stability during storage
Authors: Fregapane Giuseppe , Lavelli Vera , León Sonia , Kapuralin Jasenka , Desamparados Salvador M.
Published: February 2006

The effect of filtration and dehydration on the stability and quality of virgin olive oil during storage at room temperature (25 °C) and under accelerated conditions (40 °C) was studied. Different types of monovarietal olive oil, namely unfiltered (UF), filtered (F) and filtered‐dehydrated (FD), were obtained from Arbequina, Colombaia, Cornicabra, Picual and Taggiasca cultivars. Results showed that filtration and dehydration decreased the rate of hydrolysis of the triacylglycerol matrix, especially at the higher temperature and in oils with a higher initial free acidity (e.g. free acidity of 0.82% and 0.63% in UF and FD Colombaia samples, respectively, after 8 months of storage), and delayed the appearance of rancid defects (e.g. UF and FD Arbequina samples lost extra‐virgin grade after 10 and 12 months of storage, respectively). The formation of simple phenols due to the hydrolysis rate of their secoiridoid derivatives was also greater in unfiltered olive oils (e.g. 174 μmol/kg and 137 μmol/kg in UF and FD Picual samples, respectively, after 8 months of storage). Thus, filtration and especially dehydration could help to prolong the shelf life of high‐quality and less stable olive oils like those obtained from the Arbequina and Colombaia varieties.
Runge–Kutta time‐stepping schemes with TVD central differencing for the water hammer equations
Authors: Wahba E. M.
Published: February 2006

In the present study, Runge–Kutta schemes are used to simulate unsteady flow in elastic pipes due to sudden valve closure. The spatial derivatives are discretized using a central difference scheme. Second‐order dissipative terms are added in regions of high gradients while they are switched off in smooth flow regions using a total variation diminishing (TVD) switch. The method is applied to both one‐ and two‐dimensional water hammer formulations. Both laminar and turbulent flow cases are simulated. Different turbulence models are tested including the Baldwin–Lomax and Cebeci–Smith models. The results of the present method are in good agreement with analytical results and with experimental data available in the literature. The two‐dimensional model is shown to predict more accurately the frictional damping of the pressure transient. Moreover, through order of magnitude and dimensional analysis, a non‐dimensional parameter is identified that controls the damping of pressure transients in elastic pipes. Copyright © 2006 John Wiley & Sons, Ltd.
Playing with bone and fat
Authors: Gimble Jeffrey M. , Zvonic Sanjin , Floyd Z. Elizabeth , Kassem Moustapha , Nuttall Mark E.
Published: February 2006

The relationship between bone and fat formation within the bone marrow microenvironment is complex and remains an area of active investigation. Classical in vitro and in vivo studies strongly support an inverse relationship between the commitment of bone marrow‐derived mesenchymal stem cells or stromal cells to the adipoctye and osteoblast lineage pathways. In this review, we focus on the recent literature exploring the mechanisms underlying these differentiation events and discuss their implications relevant to osteoporosis and regenerative medicine. J. Cell. Biochem. 98: 251–266, 2006. © 2006 Wiley‐Liss, Inc.
Claw‐decompositions and tutte‐orientations
Authors: Barát János , Thomassen Carsten
Published: February 2006

We conjecture that, for each tree T, there exists a natural number kT such that the following holds: If G is a kT‐edge‐connected graph such that |E(T)| divides |E(G)|, then the edges of G can be divided into parts, each of which is isomorphic to T. We prove that for T = K1,3 (the claw), this holds if and only if there exists a (smallest) natural number kt such that every kt‐edge‐connected graph has an orientation for which the indegree of each vertex equals its outdegree modulo 3. Tutte's 3‐flow conjecture says that kt = 4. We prove the weaker statement that every 4$\lceil$ log n$\rceil$‐edge‐connected graph with n vertices has an edge‐decomposition into claws provided its number of edges is divisible by 3. We also prove that every triangulation of a surface has an edge‐decomposition into claws. © 2006 Wiley Periodicals, Inc. J Graph Theory 52: 135–146, 2006