bluuebunny/crossref_metadata_2025 huggingface dataset:
Spectrophotometric evaluation of color stability of composite resin after exposure to cold drinks: An in vitro study
Authors: Fathima J. Noor , Hashir M. Mohamed Jubair , Padmanabhan Kadambari
Published: February 2024

Objectives:

The aim of this study was to evaluate the color stability of two composite resins after exposure to beverages such as Cola, Pepsi, Red Bull, and distilled water after 15 days.

Materials and Methods:

The color stability of a microhybrid and nanohybrid composite was evaluated after storage in distilled water, Coca-Cola, Pepsi, and Red Bull for 15 days. Color measurement was done using a reflectance spectrophotometer based on the CIE L*a*b* color scale.

Results:

All tested resin composites showed color change after a period of 15 days. One-way analysis of variance and Tukey post hoc were done to assess the significance of color change within the group and an independent t-test was done to assess the change between micro and nanohybrid composite. Among the resin composites studied, microhybrid composite was found to be more color stable. The microhybrid and nanohybrid composite discolored most in Coca-Cola and Pepsi. In both groups, distilled water showed very less color change.

Conclusion:

Every endeavor should be undertaken to minimize the potential for discoloration in composite restorations by employing meticulous polishing techniques and also to use newer composite material with submicron particles. Furthermore, it is imperative to educate patients about the likelihood of the restoration being susceptible to staining from various beverages.
Modified single-step apexification and strengthening of thin dentinal walls with Biodentine
Authors: Thakur Vivek
Published: February 2024

Apexification is a technique used to create a mineralized barrier in a root having an open apex or to continue the apical growth of a root that is still not fully developed in teeth with necrotic pulps. Biodentine is a versatile material which can help in achieving apical closure as well as reinforcement of thin dentinal walls, thus improving the overall prognosis and preserving the natural dentition. In the present case, the radiographic evaluation showed thinner dentinal walls and an open apex with periapical radiolucency in relation to the upper right central incisor. The large open root apex and thin dentin walls of immature permanent teeth render them challenging to treat with root canal therapy. This case report describes a modified single-step apexification procedure and strengthening of the dentinal walls of the root canal using Biodentine.
Comparative evaluation of shear bond strength and modes of failure of five different reinforced glass ionomer restorative cements to TheraCal LC: An in vitro study
Authors: Umale Kalyani Gajanan , Gade Vandana Jaykumar , Raut Ambar W.
Published: February 2024

Aim:

The aim of the study is to evaluate and compare the shear bond strength (SBS) and modes of failure of different reinforced glass ionomer cement restorative materials such as GC IX, GC Gold Label 2 LC, Amalgomer CR, Equia Forte, and Secure Core Z to TheraCal LC.

Methodology:

A total of 50 acrylic blocks, each containing a cylindrical hole in the center were prepared from self-cure acrylic resin and randomly divided into five groups and restored, namely Group A - TheraCal LC + GC Fuji IX, Group B - TheraCal LC + GC Gold Label 2 LC, Group C - TheraCal LC + Amalgomer CR, Group D - TheraCal LC + Equia Forte, and Group E - TheraCal LC + Secure Core Z. All the specimens were stored in artificial saliva at 37°C for 24 h before testing. The statistical tests used for the analysis of the result were: one-way ANOVA, Tukey multiple comparison test, and the Chi-squared test, and P < 0.05 is considered as the level of significance.

Results:

Equia Forte showed the highest SBS, while GC type IX showed the lowest SBS with TheraCal LC.

Conclusion:

Equia Forte can be the restorative material of choice when TheraCal LC is used as a base materials for better clinical efficacy.
An unusual case of maxillary first molar with seven canals and the successful surgical recovery of a separated instrument
Authors: Kadoo Shubhangi , Patni Pallav Mahesh , Jain Pradeep , Agrawal Nikit , Raghuwanshi Swadhin , Pandey Sanket Hans
Published: February 2024

This case report highlights the intricate anatomy of root canals and the challenges they pose for clinicians. A 26-year-old female patient presented to the department with a chief complaint of pain in her left upper back tooth region. After thorough clinical and radiographical examinations, the diagnosis of pulpal necrosis with symptomatic apical periodontitis in the maxillary left first molar was confirmed. An intraoperative cone-beam computed tomography was performed. The axial imaging unveiled that there were, two distal (DB1 and DB2) canals, two palatal (P1 and P2) canals, and three mesiobuccal (MB1, MB2, and MB3) canals. The appearance of a convoluted root canal configuration serves to highlight the inherent complexity that clinicians may encounter during endodontic procedures. However, when this complexity is further compounded by the incident of separation of root canal instruments, the challenges faced by clinicians become significantly more demanding. It exemplifies the increased difficulty posed by the combination of tortuous root canal morphology and the additional complication of instrument separation, highlighting the importance of careful management and precise techniques in such scenarios and the significance of modern adjuncts, into the diagnostic process and magnification in the surgical and endodontic therapy.
Comparative evaluation of the effect of ultrasonic and rotary agitation of herbal irrigating solutions on smear layer: A SEM study
Authors: Chavate Prajhna R. , Ponnappa K. C. , Nanjappa A. Salin
Published: February 2024

Context:

Instrumentation and irrigation balance helps in effective removal of endodontic microbes housing inside the smear layer.

Aim:

This study aimed to (1) evaluate whether activation of the irrigating solutions with two different systems during the final irrigation step can lead to smear layer formation in the middle and apical third of the root canal and (2) evaluate and compare the smear layer removal ability of the aqueous extracts of Emblica officinalis and Morinda citrifolia.

Materials and Methods:

A total of 72 single-rooted teeth were prepared up to F4 ProTaper. The specimens were assigned into eight groups of nine teeth each, according to the final irrigant and activation techniques. Further, the teeth were evaluated under SEM for endodontic smear layer at the middle and apical third.

Statistical Analysis:

Inferential statistics included Pearson’s Chi-square. Level of significance was set at 0.05 at 95% confidence level.

Results:

Ultrasonic activation system showed significant (P = 0.000) amount of smear layer compared to XP-Endo Finisher file. A significant difference (P = 0.00) in the smear layer removal was observed when 6% M. citrifolia was activated with XP-Endo Finisher file both in the middle and apical third.

Conclusion:

Within the limitations of this in vitro study, it can be concluded that smear layer formation was noted with ultrasonic and XP-Endo Finisher file when saline was used as an irrigant. 6% M. citrifolia when activated with XP-Endo Finisher file showed best results among all other experimental groups.
Investigating the accuracy of Johnson’s rule in estimating fetal weight
Authors: Alidoosti Fariba , Valiani Mahboubeh , Pirhadi Masoume
Published: February 2024

BACKGROUND:

Birth weight has a significant impact on perinatal mortality. Therefore, the estimation of fetal weight greatly influences the policies necessary for care during and after delivery. We aimed to investigate Johnson’s rule in estimating fetal weight.

MATERIALS AND METHOD:

This study was a single-group longitudinal study that was conducted in 6 months from October 2021 to April 2022 on 150 pregnant women in Isfahan-Iran. The sampling method was accessible. Inclusion criteria include being term, singleton, without abnormality, intact membranes, cephalic presentation, and exclusion criteria include diagnosed polyhydramnios or oligohydramnios and mother’s abdominal or pelvic known masses. After completing the informed consent, fetal weight was estimated by Johnson’s rule and was compared with the birth weight. Descriptive and analytical statistics (mean-standard deviation (SD), number-percentage, t-paired, and Spearman’s correlation coefficient) were used to achieve the objectives of the study. The receiver operating characteristic (ROC) curve was also used to determine the sensitivity, specificity, and positive and negative predictive value of Johnson’s law.

RESULT:

The mean (SD) birth weight was 3032.88 ± 481.11 g and the mean (SD) estimated fetal weight (EFW) by the clinical method was 3152.15 ± 391.95 g. There was a significant difference between the averages (P < 0.001). The percentage error of EFW showed a significant negative correlation (r = -0.286; P < 0.05) with gestational age (GA) and a significant positive correlation (r = 0.263; P < 0.05) with the fetal head station. The sensitivity and specificity of EFW with Johnson’s rule, in normal fetal birth weight, were higher than in low birth weight fetal. The accuracy of EFW with ± 10% of the actual weight was higher in average for gestational age (AGA) (84.3%) and high-for-gestational-age (LGA) (70%) than in low-for-gestational-age (SGA) (4%). The EFW mean percentage error in SGA was higher than in the other two weight groups. This method, especially for AGA and LGA fetuses, can be a suitable alternative to other weight estimation methods.

CONCLUSION:

Clinical estimation of weight via Johnson’s rule due to availability and no cost can be a suitable method for managing childbirth based on fetal weight.
A qualitative study on barriers and strategies to hospital preparedness against chemical, biological, radiological, and nuclear incidents
Authors: Baikmohammadi Saeid , Amirheidari Bagher , Dehesh Tania , Moghadam Mahmood Nekoei , Yazdi-Feyzabadi Vahid , Hassani Ebrahim , Habibzadeh Hossein
Published: February 2024

BACKGROUND:

The effects of chemical, biological, radiological, and nuclear (CBRN) incidents on human society can be irreparable. Preparing the health system for these incidents is essential. This study aims to identify obstacles to hospital preparedness against CBRN incidents and provide solutions.

MATERIALS AND METHODS:

This qualitative study was conducted using semi-structured interview method in 2022. The research community included experts in the fields of CBRN, and 17 persons were included in the study through purposive sampling. The interviews were collected by interview guide and recorded face-to-face and online and were analyzed using thematic content analysis method in MS Word 2016.

RESULTS:

The interviews’ analysis was classified into two main categories and 34 sub-categories. Some of the most important obstacles to the hospital preparedness against CBRN incidents were the lack of proper crisis management, the lack of specialist staff, the stress of employees, the lack of turnover and sufficient rest for employees, legal gaps, and so on. The main strategies were determining the type and extent of the risk factor, strong crisis management, the lack of parallelism, continuous monitoring, having a protocol and road map, appropriate training programs, having skilled personnel, rapid response of personnel, positive attitude of the staff, and the favorable condition of the building.

CONCLUSION:

The appointment of an expert in the field of CBRN and having a specialized unit, the existence of specialized and trained staff along with access to the required facilities, clear instructions, and intra-departmental and inter-departmental cooperation affect the readiness of hospitals against CBRN incidents.
The effect of iron supplementation on menstrual bleeding volume and hemoglobin level during menstrual bleeding : A randomized clinical trial
Authors: MokhtarKalimi Elnaz , Loripoor Marzeyeh , Rezaeian Mohsen , Gholamrezapour MohammadReza
Published: February 2024

BACKGROUND:

Many women around the world avoid taking iron supplements during their menstrual bleeding, thinking that menstrual bleeding will increase after taking these supplements. Due to the lack of relevant scientific evidence in this regard, this study was performed to determine the effect of iron supplementation on menstrual blood volume and hemoglobin level during menstrual bleeding.

MATERIALS AND METHODS:

In this three-blind randomized clinical trial, 160 non-anemic female students of Rafsanjan University of Medical Sciences were selected through a public call and then they were randomly assigned to two intervention and control groups. The intervention group was given a ferrous sulfate tablet containsing 50 mg of elemental iron daily in the first four days of bleeding for three consecutive menstrual cycles, and the control group received a placebo simultaneously. Before and after the intervention, the level of hemoglobin was measured and the Higham chart was completed in each menstrual cycle by the participants of the two groups. The obtained data were analyzed using the SPSS software version 21 and Chi-square, independent t-test, paired t-test, analysis of variance with repeated measures, and nonparametric tests.

RESULTS:

Before performing the intervention, the mean Higham score and hemoglobin level of the two groups were not statistically significant (P = 0.307, P = 0.670). The mean Higham score after each intervention was not statistically significant between the two groups over time or when considering the interaction of the time group (P = 0.77, P = 0.916). The hemoglobin level of these two groups did not change significantly after the intervention compared with that before the intervention (P = 0.444).

CONCLUSION:

Compared with a placebo, taking iron supplements containing 50 mg of elemental iron during the first four days of menstrual bleeding in non-anemic women did not change the volume of menstrual bleeding and hemoglobin level.
Is fat-to-lean mass ratio a better predictor of heart variability than body mass index?
Authors: Aggarwal Piyush , Kuppusamy Saranya , Prakash Praveen , Subramanian Senthilkumar , Fredrick Jean
Published: February 2024

BACKGROUND:

Body mass index (BMI) may not accurately predict cardiometabolic risk due to confounders like age, gender, relatively high lean mass, and the “thin-fat phenotype” prevalent in south Asian populations. Fat-to-lean mass ratio (FTLM), which assesses the balance between fat and lean body mass, may provide a more complete assessment of cardiometabolic health.

MATERIALS AND METHODS:

This cross-sectional analytical study investigated the relationship between FTLM ratio, BMI, and heart rate variability (HRV) in apparently healthy male adults. 88 participants recruited through convenience sampling underwent anthropometric assessments, bioimpedance body composition analysis, and HRV testing. Pearson’s or Spearman’s correlation and linear regression analyses were performed where appropriate to assess the relationship between FTLM ratio, BMI, and HRV.

RESULTS:

Both BMI and FTLM showed significant positive correlation with normalized LF power and LF-HF ratio and a negative correlation with normalized HF power, RMSSD, and pNN50. However, FTLM ratio showed a stronger association with HRV parameters than BMI and could explain a greater percentage of the variability in LF-HF ratio (32% compared to 18.4%, P < 0.001).

CONCLUSION:

Assessment of both fat and lean mass, expressed as a ratio, is a better index of quantifying adiposity and predicting the influence of altered body composition on cardiometabolic health.
Association of heart rate variability and C-reactive protein in patients with depression
Authors: Singh Soni , Singh Shraddha , Shukla Neeraja , Shukla Abhishek
Published: February 2024

ABSTRACT

Background:

Depression has been shown to be correlated with cardiovascular (CV) morbidity and mortality. Inflammation and autonomic nervous system (ANS) dysfunction are possible causes. Numerous clinical studies have found an association between inflammatory pathways and the ANS. The aim of this study was to investigate the relationship between different heart rate variability (HRV) parameters and C-reactive protein (CRP) levels in depressed patients without concomitant diseases.

Materials and Methods:

Sixty-five depressed patients who were not taking medication participated in this cross-sectional study. The Tenth Revision of the International Classification of Diseases and Related Health Problems (ICD-10) categorization of mental and behavioral disorders served as the basis for the diagnosis of depression. HRV processing and analysis were performed using ADInstrument’s Pro LabChart (PowerLab 8Pro) data analysis software. HRV was recorded for 5 min in an upright sitting position using a lead II electrocardiogram (ECG) (short-term HRV). CRP levels were measured using an ELISA (enzyme-linked immunosorbent assay) test.

Results:

None of the measures of HRV showed a significant relationship with pulse rate, systolic blood pressure, diastolic blood pressure, or body mass index (BMI). Weight and BMI were strongly positively related (r = 0.420, P = 0.003) to pRR50 (percentage of successive RR intervals differing by more than 50 ms). Very low frequency (VLF), low frequency (LF), and the LF/HF (high frequency) ratio were all strongly positively correlated with CRP (r = 0.595, P = 0.001), whereas HF was also significantly negatively correlated (r = 0.383, P = 0.007). CRP had a significant negative correlation with the logarithm (ln) HF and a significant positive correlation with lnVLF, lnLF, and lnLF/HF.

Conclusion:

Measurement of resting HRV and CRP may be helpful in detecting CV disease in depressed patients. Low HRV and elevated serum CRP should prompt physicians to begin treatment for risk CV as soon as possible.
Efficacy of combination therapy with unkeito and boiogito for menopausal arthralgia: A retrospective observational study
Authors: Nogami Tatsuya , Taniguchi Daigo , Miyatake Noriko , Tsuruta Toko , Arai Makoto
Published: February 2024

ABSTRACT

Context:

Arthralgia affects menopausal patients.

Aim:

Here, we report a retrospective observational study evaluating the therapeutic efficacy of a combination of unkeito and boiogito for menopausal arthralgia.

Settings and Design:

Patients treated with a combination of unkeito and boiogito for menopausal arthralgia between April 2020 and October 2022 at three Japanese Kampo outpatient clinics were retrospectively examined. Treatment effectiveness was determined based on the patient’s description of pain. Adverse events associated with this treatment regimen were also recorded. The study design was approved by the Tokai University Ethics Committee (Approval number: 22R196).

Methods and Material:

This study was conducted by retrospectively analysing the medical records of patients who attended the three medical facilities. All patients received Kampo medicines based on traditional medical diagnoses. Outpatients with a diagnosis of menopausal arthralgia were selected, and information on those who were treated with a combination of unkeito and boiogito was collected.

Statistical Analysis:

The age, height, and weight of all patients are represented as the mean ± standard deviation. Statistical analyses were not performed in this study as there was no comparison group.

Results:

During the study period, nine patients with menopausal arthralgia received the unkeito and boiogito combination. Four patients showed a “significant” response to the combination treatment, four showed an “effective” response, and one patient showed an “ineffective” response. One patient reported headache as an adverse event.

Conclusion:

The combination of unkeito and boiogito may be effective in the treatment of menopausal arthralgia.
Undernutrition and its determinants among under-five children in a tribal community of Meghalaya
Authors: Singh Aabha , Sundaram Shanthosh P. , Ningombam Joenna Devi
Published: February 2024

ABSTRACT

Background and Objectives:

Malnutrition among under-five children is a rampant and major public health problem in developing countries. The paucity of studies on undernutrition among tribals made it imperative to determine the prevalence and the factors associated with undernutrition among the tribal under-five children.

Materials and Methods:

A community-based cross-sectional analytical study was conducted among 196 under-five children residing in the village under the rural field practice area of North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences (NEIGRIHMS), Meghalaya. Sociodemographic and clinical data were collected using a pretested semi-structured questionnaire, and burden of food insecurity was collected using the Food Insecurity Experience Scale Survey Module (FIES-SM). Anthropometric measurements, such as height, weight, and mid-upper arm circumference, were measured for all the children, and Z-scores were calculated for weight for age, height for age, and weight for height.

Results:

Of the 196 children, the mean age of the children was 36.7 (15.3) months. The prevalence of underweight, stunting, and wasting was 9.2% (95% confidence interval (CI): 5.7%–14.3%), 28.6% (95% CI: 22.5%–35.5%), and 6.1% (95% CI: 3.3%–10.7%), respectively. There was a significant association for girls, birth weight, and age of the mother during first childbirth and immunization status with underweight. Similarly, there was a significant association for girls with wasting and education of the mother and birth weight with stunting.

Conclusion and Recommendations:

The prevalence of underweight wasting and stunting was lesser with an observable enhancement in the nutritional status of the children; however, the undernutrition status is still alarming, which warrants health and nutritional education along with behavioral change communication.
Effect of pranayama on sympatho-vagal imbalance and cognitive deficit in premenstrual syndrome
Authors: Feula A Jothi Marie , Yerrabelli Dhanalakshmi , Pal Gopal Krushna
Published: February 2024

ABSTRACT

Context:

Premenstrual syndrome (PMS) is a prevalent and often neglected condition that affects around 80% of women of reproductive age. In PMS, abnormal fluctuations in gonadal hormones cause altered homeostasis, resulting in sympatho-vagal imbalance and poor cognition.

Aim:

To compare autonomic function parameters and cognitive performance between PMS and control groups, and to study the effect of pranayama on the above parameters in PMS women.

Settings and Design:

It was a randomized control trial.

Materials and Methods:

We recruited 40 women of reproductive age who fit the inclusion criteria. They were asked to complete the Premenstrual Syndrome Screening Tool (PSST) questionnaire and were categorized as having PMS (n = 20) or not having PMS (n = 20). All study participants had their baseline CAFT, HRV, BRS, P300, and MOCA values recorded. Following that, participants in the PMS group were divided into two groups of ten at random. For 8 weeks, one group received pranayama training. Following that, all baseline data were recorded again in both the pranayama and no-intervention groups.

Statistical Analysis Used:

SPSS version 20 was used to analyze the data. For parametric data, the unpaired t test was used to compare between the PMS and no PMS groups, whereas the Mann–Whitney U test was employed for non-parametric data. To compare the parameters before and after intervention, the Students paired ‘t’ test for parametric data and the Wilcoxan-signed rank test for non-parametric data were used.

Results:

According to the findings, autonomic function and cognition were considerably affected in the PMS group and improved significantly in the PMS group following pranayama intervention.

Conclusion:

Pranayama is an effective and safe non-pharmacological method for treating PMS and improving women’s quality of life.
Effect of vaginal douching with normal saline before insertion of dinoprostone vaginal insert for labor induction
Authors: Verma Manju Lata , Pandey Manjari , Singh Uma , Sachan Rekha , Sankhwar Pushp Lata
Published: February 2024

ABSTRACT

Objective:

Vaginal pH has been suggested to be one of the causative factors, responsible for variation in prostaglandin efficacy for induction of labour. The purpose of this study was to analyse the effect of vaginal douching with normal saline before insertion of dinoprostone vaginal insert for induction of labour.

Methods:

This randomised controlled study was done in the Department of Obstetrics and Gynaecology for a period of 1 year. Using a computer-generated random number table, subjects were allocated in two groups. In group A (study group), vaginal douching was done with 20 cc of sterile 0.9% NaCl and vaginal pH was again measured with pH paper strips just before inserting dinoprostone pessary. Dinoprostone pessary was inserted without douching in group B (control group).

Results:

There was a significant increase in the vaginal pH after douching with normal saline (4.91 vs 5.52, P < 0.001). Mean intrinsic vaginal pH (pH before inserting dinoprostone insert) in women who delivered vaginally was significantly higher than that of the women who had a caesarean section (5.10 vs 4.63, P < 0.001). Time interval between dinoprostone insertion to active phase of labour, duration of active phase of labour, time interval between dinoprostone insertion, and complete cervical dilatation and mode of delivery were not significantly different between the two groups.

Conclusion:

Although douching with normal saline increases vaginal pH, douching does not help in increasing the chances of vaginal delivery because it gives a transient effect. Rather, it is intrinsic vaginal pH, which is a better decisive factor for successful vaginal delivery.
Impact of lockdown due to COVID-19 pandemic on neurobehavioral profile of children aged 6–12 years (NeuBeC study)
Authors: Pasi Rachna , Ravi Kumar Satish , Babu Thirunavukkarasu Arun , Jamir Limalemla , Aravindakshan Rajeev
Published: February 2024

ABSTRACT

Background:

The lockdown due to the COVID-19 pandemic has affected the lives of children and resulted in behavioral and emotional disturbances in children. This study was planned to identify the prevalence of these problems in Indian children. The aim of the study was to estimate the effect of lockdown on the neurobehavioral profile of children 6–12 years of age by using the Child Behavior Checklist (CBCL) scale. CBCL is the most widely used validated scientific tool to detect behavioral and emotional problems in children.

Materials and Methods:

All children 6–12 years of age who were fulfilling the inclusion criteria of the study were included from all over India through an online Google form link. The children attending the outpatient department (OPD) at our tertiary-level care medical college were also included in offline mode. Data were collected and entered in an Excel sheet and analyzed statistically.

Results:

A total of 173 children in the age group 6–12 years were enrolled. The mean standard deviation (SD) age of all children was 8.88 (1.84) years, out of which males were of a mean age of 9.2 (1.84) years and females were 8.44 (1.74) years. Total CBCL T-scores (mean (SD)) for internalizing, externalizing, and total scores were 63.07 (7.98), 63.95 (6.51), and 62.39 (4.9), respectively.

Conclusion:

Lockdown has resulted in neurobehavioral changes in normal children. The independent predictors found were the increase in screen-based media use, sleep issues, or behavioral changes like aggression due to restriction of their mobility or confinement. Females exhibited more internalizing problems, and males exhibited more externalizing problems.
Attributes of hypertension among industrial workers in Northern India - An alarming signal
Authors: Goyal Pooja , Goyal Gajinder K. , Yadav Kriti , Bhatt Anshuman , Nassa Khushboo , Raushan Suman K. , Aggarwal Dhairya , Dagar Rakesh
Published: February 2024

ABSTRACT

Context:

There has been an increasing prevalence of hypertension (HTN) affecting all populations of the world including the special occupational groups and industries workers.

Aims:

To estimate the prevalence of hypertension and to determine the associated factors among industrial workers in the Haryana state of India.

Settings and Design:

A cross-sectional study was conducted among 323 industrial workers of Faridabad, Haryana.

Materials and Methods:

A semi-structured and validated questionnaire was used to collect information regarding sociodemographic characteristics of the workers, their personal habits, and occupational history. The investigator also recorded the height, weight, blood pressure, blood glucose, and lipid profile of the workers.

Statistical Analysis Used:

Analysis of the data was done using SPSS Vs 21.

Results:

The prevalence of hypertension among industrial workers was 48.6%. Age of the worker, presence of smoking or alcohol consumption, having a longer duration of employment, and having deranged total cholesterol/TG/LDL-C levels, diabetes, or obesity were found to be independently associated with hypertension.

Conclusion:

Screening is required for early detection and prevention of complications. Lifestyle modification is of utmost importance. Employers should implement guidelines issued by the government to protect the health of the productive population.
A comparative study of NS1 and IgM using enzyme-linked immunosorbent assay and immunochromatography test for detection of dengue
Authors: Chakraborty Debapriya , Kar Harapriya , Hodiwala Anahita V. Bhesania
Published: February 2024

ABSTRACT

Background:

Dengue is the most common arboviral infection that spreads by Aedes aegypti and Aedes albopictus mosquitoes, and is quickly gaining prominence as a major mosquito-borne viral disease. One of the major public health issues is dengue fever (DF), which can also cause dengue haemorrhagic fever (DHF) and dengue shock syndrome (DSS). Therefore, this study focused on comparison of dengue antigen non-structural protein (NS1) and immunoglobulin M (IgM) using enzyme-linked immunosorbent assay (ELISA) and immunochromatography test (ICT) for detection of dengue.

Method:

In a Tertiary Care Hospital (TCH), sociodemographic status of probable dengue cases from February 2021 to February 2022 was studied. The results of the Dengue Antigen NS1 and IgM ICT, Dengue NS1 Microlisa, and Dengue IgM Microlisa were compared in order to determine the effective one at managing patients and preventing complications like DHF and DSS.

Results:

In distribution of 100 ICT reactive samples, 50% were NS1 reactive and 50% were IgM reactive. One hundred ICT reactive samples were further processed for IgM antibody capture enzyme-linked immunosorbent assay (MAC-ELISA) for both NS1 and IgM. Sensitivity and specificity of NS1 ICT were 89.3% and 71.4% and that of IgM ICT was 88% and 64.5%. As a result of antigenic cross-reactivity, false positive cases were reported. Platelet count of the patients was correlated with an optical density (OD) value of ELISA for both NS1 and IgM. In the present study, patients having low platelet count showed high OD value.

Conclusion:

In cases of severe thrombocytopenia (platelet count <50000), early diagnosis by screening ICT and confirmation by ELISA (NS1 and IgM) would reduce the complications like DHF and DSS.
Prevalence of depression among diabetic patients attending the Armed Forces Hospital, Southern Region, Saudi Arabia: A prospective cross-sectional study
Authors: Khiro Malak A. K. , Alshahrani Ali A. S. , Jabali Shahad H. Y. , Alyahya Yasser A. M. , Alamri Moneer M.
Published: February 2024

ABSTRACT

Background:

Depression associated with diabetes is one of major obstacles in diabetic patient management. This study aims to determine the prevalence of depression and its associated risk factors among diabetic patients of both types (I and II).

Materials and Methods:

A cross-sectional analytical study was conducted at Armed Forces Hospital, Southern Region, Kingdom of Saudi Arabia, among adult diabetic patients attending the diabetic center. An interview-validated questionnaire was utilized to collect data. It consists of three main parts: demographic data, diabetic assessment tool, and patient health questionnaire-9.

Results:

A total of 386 diabetic patients were included. The age of them ranged between 17 and 95 years with an arithmetic mean of 53.4 years and a standard deviation of ± 18.2 years. Almost two-thirds (62.2%) were males. The prevalence of depression among diabetic patients was 48.2%, mostly of mild (31.4%) or moderate severity (12.7%). Multivariate logistic regression analysis revealed that female diabetic patients were at almost double-fold risk of developing depression compared to males [adjusted odds ratio (AOR) =2.73, 95% confidence interval (CI): 1.70–4.38], P < 0.001. Also, type II diabetic patients were at almost double-fold risk of developing depression compared to type I diabetic patients (AOR = 2.07, 95% CI: 1.16–3.67), P = 0.013. Patients with history of any social issue with the family, relatives, or friends were at about three-fold risk of developing depression compared to those without such history (AOR = 3.45, 95% CI: 2.11–5.66), P < 0.001. Patients who reported compliance to diet were at higher risk for developing depression compared to their peers (AOR = 2.57, 95% CI: 1.25–5.28), P = 0.010, while those compliant to physical activity about 150 min/week or more were at significant lower risk to develop depression (AOR = 0.56, 95% CI: 0.35–0.89), P = 0.015. Patients with nephropathy or neuropathy were more likely to have depression compared to their counterparts (AOR = 2.52. 95% CI: 1.33–4.80, P = 0.005 and AOR = 1.80, 95% CI: 1.11–2.90, P = 0.016, respectively).

Conclusion:

Depression is a very prevalent problem affecting diabetic patients, particularly those of type II, female patients, and those with nephropathy or neuropathy. Therefore, regular screening of diabetic patients for depression and referral of severe cases to psychiatric care are highly warranted.
Hyponatremia-induced worsening of trigeminal neuralgia- When the sodium plays the game
Authors: Ansari Mohammad Z. , Singh Rashmi , Mohanty Bijaya , Kumari Sarita , Sunder Ashok
Published: February 2024

ABSTRACT

A 78-year-old elderly male who was on treatment for trigeminal neuralgia and hypertension was brought to the emergency with altered sensorium. His vital parameters were within normal limits; however, the arterial blood gas analysis showed severe hyponatremia. He was admitted to the ward, where further workup was carried out and hyponatremia correction started. He had a sudden worsening in his facial pain before he landed in encephalopathy. His medications (oxcarbazepine and chlorthalidone) that could cause hyponatremia were stopped, and judicious correction of hyponatremia was done. His baseline investigations, including a chest roentgenogram and electrocardiogram, were normal. After he regained consciousness, it was noted that the facial pain had regressed significantly despite stopping his first-line drugs. This case of worsening trigeminal neuralgic pain due to hyponatremia responded well to judicious sodium correction.
A cross-sectional study on quality of life of survivors of sexual assault
Authors: Nath Anamika , Thakuria Pradip K. , Gogoi Nitu K.
Published: February 2024

ABSTRACT

Sexual assault is a grave violation of an individual’s fundamental rights and has a profound impact on their physical and mental health. However, there is a significant knowledge gap regarding the quality of life (QOL) experienced by survivors after such incidents. This cross-sectional study aims to evaluate the QOL of survivors of sexual assault and determine the factors that affect their physical and psychological domains. The study included 32 survivors, and data were collected using the WHO-QOL questionnaire and the modified Kuppuswamy scale. The results showed that survivors experienced poor QOL in both physical and psychological domains. Factors such as physical injuries, pregnancy following the assault, education, and psychiatric counseling significantly influenced survivors’ QOL. The findings underscore the importance of routine psychiatric counseling, follow-up care for physical illnesses, rehabilitation, continuation of education and employment, and early detection of pregnancies to improve the QOL for survivors of sexual assault.
Acute renal failure and hepatopathy consequent upon ingestion of cooked gallbladder of Indian carp: A case report
Authors: Singh Sudipta R. , Sahu Sindhu S. , Vasudevan Greeshma , Thamizhraj M. , Mohanty Manoj K.
Published: February 2024

ABSTRACT

Among freshwater fishes, the Indian Carp (Labeo rohita, “ROHU”) is one of the most chosen species for Indian diets, but reports of toxicity are rare. This report is of a middle-aged healthy female who developed pain in the abdomen, vomiting, and diarrhea within hours of ingestion of a cooked portion of Indian carp’s intestines and gallbladder. There was an inadvertent delay in diagnosis over 1 week due to the rarity of incidence and non-availability of a definite diagnostic indicator coupled with the lack of awareness and high index of suspicion. However, the patient could finally be diagnosed and treated appropriately after roving around many hospitals and then had life-threatening complications such as acute renal failure and hepatopathy, requiring repeated hemodialysis and supportive treatment before being fit for discharge. In this report, a detailed discussion of the clinical course and toxicological aspects are enumerated with a cautious note to spread awareness to facilitate prompt diagnosis.
Preventive hepatology at AIIMS Rishikesh: Delivering comprehensive and integrated care for liver diseases in Northern state of India
Authors: Bhadoria Ajeet Singh , Saxena Gaurika , Pandey Pragya , Mehndiratta Amrita , Sadasivan Abhishek , Gupta Rohit , Singh Meenu , Nundy Samiran
Published: February 2024

ABSTRACT

Globally, liver diseases accounts for 4% of all deaths. Annually, over 2 million deaths occur due to preventable causes of chronic liver diseases and liver cancer like fatty liver diseases (alcoholic or non alcoholic) and viral hepatitis B and C. The burden of chronic liver diseases are increasing, and the epidemiology and demographics of people affected by these diseases are changing. Policy changes, vaccination, screening, lifestyle changes and public health awareness is the key to curb down liver disaeses. To achieve the ultimate goal of reducing mortality and linkage to care for those who need specialized care for liver disease, it is vital to have dedicated preventive hepatology clinics in sync with existing liver or gastroenterology clinics at tertary care level.
Ethics sensitivity among dialysis nurses in Jazan region: A descriptive cross-sectional study
Authors: Rajhi Fatma A. , Koura Hussein , Hussein Ghaiath
Published: February 2024

ABSTRACT

Background:

Ethical sensitivity is defined as paying attention to ethical ideals in a conflict situation and being conscious of one’s own role and duty in that situation. One essential element of ethical conduct is the ability to recognize and respond to ethical dilemmas. Lack of or diminished ethical awareness is a breach of nursing’s professional obligation since it can lead to morally incongruent treatment. Thus, the purpose of this study is to assess the hemodialysis nurse’s ethical awareness in Jizan, Saudi Arabia.

Materials and Methods:

In this prospective cross-sectional study, based on these study criteria, we have enrolled 300 nurses from five different hospitals in Jizan, Saudi Arabia. During the epidemic, an online questionnaire study was distributed, and enrolled nurses signed an electronic consent form.

Results:

Data obtained were statistically analyzed. Clinical data include age (32.3 ± 5.5), gender (F: 78.7%-M: 21.3%), educational level (diploma/bachelor-48% and master/PhD-4%), experience (1-5 years = 28%, 6-10 years = 36%, 11-15 years = 24.7%, and above 15 years = 11.3%), and no nurses were found to be in nursing practice ethics. The total sensitivity rate was determined to be 107 ± 15.6. Caring by connecting with others (15.9 ± 3.1) and generating interpretation and options (16.2 ± 3.1) obtained the highest mean scores among the seven subscales. Taking others’ perspectives (14.4 ± 3.2) and identifying the repercussions of actions and options (14.8 ± 2.6) on the other hand. The study also discovered a statistically significant relationship between ethical sensitivity subscales and age, country, and years of experience. The relevance of generating interpretations and possibilities with age (P < 0.05), reading and expressing emotions and nationality (P < 0.05), and years of experience with reading and expressing emotions (P < 0.05) were specifically mentioned.

Conclusion:

This study concludes that hemodialysis nurses in Jizan have a high level of ethical sensitivity. This study suggests that future studies should focus on practicing, educating, and implementing a policy proposal that enhances hemodialysis nurses’ ethical awareness when providing nursing care.
Knowledge, attitudes, beliefs and practices of pregnant women towards the influenza vaccine in Trinidad
Authors: Khan Raveed , Benjamin-Niles Janisse
Published: February 2024

ABSTRACT

Background:

Pregnant women and their babies are at increased risk of influenza-related complications. The World Health Organisation recommends influenza vaccination to this high-risk population as the highest priority.

Methods:

A knowledge, attitudes,beliefs, and practices (KAP) of pregnant women towards the influenza vaccine in Trinidad. It was disseminated to 480 pregnant women attending the clinic and completed by 146 yielding a response rate of 30%.

Results:

Women who received the vaccine in a past pregnancy were nine times more likely to consider taking the vaccine in the current pregnancy. There was a statistically significant difference in vaccine uptake based on the source of information received by participants about the influenza vaccine (χ2 (3) = 9.864, P = 0.020), with the highest mean score for uptake shown in women who received information from a health care provider. A moderate, positive correlation was found between knowledge and vaccine uptake (rs (143) =0.430, P < 0.01), a weak, positive correlation between perceived susceptibility and vaccine uptake (rs (143) = 0.264, P < 0.01), and a weak, positive correlation between knowledge and perceived susceptibility (rs (143) = 0.229, P < 0.01).

Conclusion:

The study findings highlight that the source of information significantly influences vaccine uptake, with health care providers being the most influential source. This underscores the role of primary care physicians in providing accurate and up-to-date information about influenza vaccination to pregnant women. There is a need for accurate information and recommendations to be given to pregnant women by all health care workers including primary care physicians in order to increase vaccine uptake and reduce maternal and neonatal morbidity and mortality.
An interventional study evaluating the NTCP (NATIONAL TOBACCO CONTROL PROGRAM) guidelines-based education model in semi-urban school population
Authors: Chitlange Pooja , Reche Amit , Madhu Priyanka Paul , Chhabra Kumar Gaurav , Sheikh Tarannum B. , Kewelramani Muskan
Published: February 2024

ABSTRACT

Background:

The present study was carried out to assess the awareness of the adverse consequences of tobacco use in the semi-urban school population in Wardha district because tobacco use in schools is a significant concern and is rising at an alarming rate. The purpose of the current study was to assess the prevalence of tobacco use among students and teachers as well as their knowledge of the negative effects of tobacco use. It also aimed to educate students and teachers about these effects and assess the effectiveness of the intervention.

Methodology:

A total of 350 students from a semi-urban school in the Wardha area participated in this study. Pre-tests were administered to a group of chosen kids and instructors to gauge their familiarity with tobacco. After the pre-test data were analyzed, teachers were offered intervention. PowerPoint presentations, posters, and models were used to educate them about the dangers of tobacco usage for dental health. There were discussions, role plays, and skits done. After the instruction, the students took a post-test to gauge how well they understood what they had learned.

Results:

The recent study is a significant step toward the semi-urban school population quitting smoking. Overall, the study involves testing participants’ knowledge, teaching them about tobacco’s negative consequences, and inspiring habitual smokers to completely kick the habit. The majority of the NTCP questionnaire’s elements were significant when compared to knowledge of tobacco use and its components (*p0.05; significant).

Conclusion:

The suggested study is a significant step toward the semi-urban school population quitting smoking. The research will provide a genuine and dependable change and help promote optimal dental health.
Readiness, acceptability, and feasibility of differentiated TB care for COVID-positive pulmonary tuberculosis patients diagnosed in a district in South India: Mixed methods study
Authors: Kamalasundar T , Vengadapathy R , Surekha A , Pruthu TK , Suryawanshi Deodatt M. , Rajaseharan Divya , Anbazhagan Suguna
Published: February 2024

ABSTRACT

Background:

Differentiated tuberculosis care (DTC) approach is the need of the hour to mitigate those risks and provide better treatment outcomes to reduce both mortality and morbidity. Before implementing such an approach, there should be adequate literature on healthcare facility assessment along with qualitative exploration on readiness and acceptability among various stakeholders that are currently needed to fill the gaps in National Tuberculosis Elimination Program.

Objectives:

Our study objectives were to assess the availability of equipment, treatment, and investigations for managing patients under the DTC approach, to explore the readiness, acceptability, and feasibility of the DTC approach among healthcare providers involved in TB care provision, and to determine the knowledge regarding DTC approach among healthcare providers delivering TB care for COVID-positive pulmonary TB patients.

Materials and Methods:

All Peripheral Health Institutes (PHIs) in two randomly chosen blocks within the Tiruchirappalli district’s health units were selected for the healthcare facilities assessment. By the universal sampling method, all the stakeholders were included. The study population was assessed for their knowledge regarding DTC. Checklist-based assessment of the feasibility of healthcare services followed by a questionnaire-based knowledge assessment was done. An in-depth interview-based exploration of readiness and acceptability of the DTC approach was conducted. This study was conducted among various stakeholders involved in TB care in selected PHIs of Tiruchirappalli from July 2022 to October 2022.

Results:

The majority of healthcare workers (HCWs) are unaware of bidirectional screening (89.0%) and lack training in providing TB care to COVID-co-infected patients (87.8%), although the majority were aware of risk stratification for TB patients (90.2%) and are linking TB with other co-morbidities (82.9%). About 62.2% of HCWs claimed they are not using information communication technology-based services to receive lab findings from public scans and laboratory centers, and more than one-third were unaware of these facilities. Based on the qualitative assessment, most of them were willing to undergo periodic training to improvise their approach and treatment. Also, most of the HCWs felt manpower can be increased for the specific care of the patients.

Conclusion:

The research suggests that with sufficient training and upskilling of the HCWs, DTC is almost feasible and that HCWs will accept it if specific strategies are used. More studies like these in assessing the feasibility and acceptability of this DTC approach and exploring the challenges and solutions will help the policymakers in finding the lacunae before implementing this DTC model in various states across India.