bluuebunny/crossref_metadata_2025 huggingface dataset:
Quantitative Analysis of Fat-Soluble Vitamins in Feed Additives Using an In-House Developed and Validated HPLC Method
Authors:   1 Quality Control Laboratory, Department of Livestock Services, Bangladesh, MZ Hosain , SMS Islam ,   1 Quality Control Laboratory, Department of Livestock Services, Bangladesh, MM Kamal ,   1 Quality Control Laboratory, Department of Livestock Services, Bangladesh, MM Rahman ,   Department of Environmental Sciences, Jahangirnagar University, Bangladesh
Published: January 2023

Quantification of vitamins in complex matrices such as feed additives is a time-consuming analytical procedure. In this study, a simple and precise in-house High Performance Liquid Chromatography (HPLC) method was developed and validated for the simultaneous detection and quantification of four fat-soluble vitamins such as vitamin A, D3 , E, and K3 in feed additives. The HPLC method was developed and validated using reversed-phase column chromatography. The chromatographic separation of the vitamins was carried out at 25° C temperature on a reverse-phase C18 column using a binary gradient pump mode. Mobile phase constituents were solvent (a): deionized water and (b) methanol. Detection was performed with HPLC ultraviolet/visible detection set at 325, 265, 230, and 254 nm wavelength for vitamin A, D3 , E, and K3 respectively. The flow rate was 1.0mL/min and the total run time was 20min. The method was validated according to the guidelines of the International Conference on Harmonization (ICH) and Food and Drug Administration (FDA), USA, and acceptance criteria for system suitability, specificity, linearity, accuracy, and precision were met in all the cases. The Relative Standard Deviation (RSD) for system suitability and precision was <2% for all the studied vitamins. The linearity of the calibration curves was excellent (R2 >0.999) at concentrations of 2.5, 5.0, 7.5, 10.0, 15.0, and 20.0 µg/mL for all vitamins, and the range of linearity of this method was 0.0-50.0 μg/mL with R2 value greater than 0.999. The limits of detection values were 0.0022, 0.0012, 0.0022, and 0.0020 µg/ mL for vitamin A, D3 , E, and K3 , respectively, and the limits of quantification values were 0.0066, 0.0038, 0.0066, and 0.0061 µg/mL for vitamin- A, D3 , E, and K3 respectively. The recovery percentages ranged from 85% to 103%, and the robustness of the method is also high with excellent reproducibility. The overall parameters of the proposed method met the validation criteria and this method could be a precise and highly desirable analytical procedure for accurate quantification of four fat-soluble vitamins such as A, D3 , E, and K3 in feed additives using a single chromatographic run.
Investigation on Chloramphenicol Residues in Poultry Meat in Bangladesh Using a Validated Liquid Chromatography-Tandem Mass Spectrometry
Authors:   Quality Control Laboratory, Department of Livestock Services, Savar, Dhaka, Bangladesh, MZ Hosain , SMS Islam ,   Quality Control Laboratory, Department of Livestock Services, Savar, Dhaka, Bangladesh, MM Kamal ,   Quality Control Laboratory, Department of Livestock Services, Savar, Dhaka, Bangladesh
Published: January 2023

Chloramphenicol (CAP) is a broad-spectrum antibiotic widely applied in veterinary practices. Continual use of CAP in livestock production may lead to antibiotic resistance and health-related hazards. In this study, a rapid and highly sensitive analytical method based on ultra-performance liquid chromatographytandem mass spectrometry (UPLC–MS/MS) was developed and validated to detect and quantify there is due of CAP in poultry meat regarding the safety of humans and animals. Total 80 samples of poultry meat were collected from different poultry farms, and poultry meat sellers in three upazilas namely- Sadar, Mirzapur and Ghatail of Tangail district in the Dhaka division. The test analysis was performed using matrix-matched liquid chromatography-mass spectrophotometry. The chromatographic separation of the CA Presidue was carried out at 40°C temperature on a reverse-phase C18 column using a binary gradient pump, and quantification was performed by LC-MS/MS in electrospray mode. Mobile phase constituents were solvent (a) deionized water, and (b) acetonitrile. The flow rate was 0.35 mL/min and the total run time was 5 min. The method was validated in terms of selectivity, linearity, recovery, and precision following the 2021/808/EC guidelines and acceptance criteria were met in all the cases. The relative standard deviation (RSD) for precision was <11%. The linearity of the calibration curves was excellent (R2 >0.999) at concentrations of 0.25, 0.50, 0.75, 1.0, 2.0, and 5.0 μg/kg for matrix-matched CAP standard, and the range of linearity of this method was 0.0-5.0 μg/kg with R2 value greater than 0.99. The decision limit (CC-a), and detection capability (CCβ) were 0.29 μg/ kg, and 0.31 μg/kg respectively, and the recovery percentages ranged from 94 to 100 %. In this study, the levels of CAP residue in tested poultry meat samples were found below the detection limit. The overall parameters of the proposed method met the validation criteria, and the method proved to be suitable for CAP residues determination in poultry meat samples. Thus, this method could be a precise and highly desirable analytical procedure for rapid and routine analysis of CA Presidues in poultry meat, and obtained tested results in this study could be an authentic data to ensure the chloramphenicol free safety poultry meat for human consumption.
Appraisal and Validation of a Method (MVU-AAS) Used for the Detection of a Toxic Metal Mercury (Hg) in Poultry Feed Available in Bangladesh
Authors:   Quality Control Laboratory, Department of Livestock Services, Bangladesh, MM Hossain , ASMA Hannan ,   Quality Control Laboratory, Department of Livestock Services, Bangladesh, MM Kamal ,   Quality Control Laboratory, Department of Livestock Services, Bangladesh, MA Hossain ,   Department of Dairy and Poultry Science, Chattogram Veterinary and Animal Sciences University, Chattogram, Bangladesh, SB Quraishi ,   Analytical Chemistry Laboratory, Atomic Energy Centre, Bangladesh Atomic Energy Commission, Dhaka, Bangladesh
Published: January 2023

Toxic metal mercury (Hg) in poultry feed might affect seriously on the environment and human being. So continual or gradual analyses of toxic metal contents in poultry feedstuff are of prime significance for assessing the feed quality and consumer safety. In this study, a method named Mercury Vapor Unit Atomic Absorption Spectrometry (MVU-AAS) was used to analyze the content of Hg in poultry feed in compliance with the Council Directive 333/2007/EC, Commission Decision 657/2002/EC. The metal Hg was analyzed from the feed sample inthe laboratory by MVU-AAS (Model: AA-7000 Shimadzu, Japan) and the absorbance was read at 253.65 nm wavelength, The method was confirmed and validated by complying with the international guidelines and assessing a number of criteria say system suitability, precision studies, linearity check, uncertainty measurement and recovery % etc.. The results revealed that the coefficient of variation (CV%) for system suitability and precision was <10% for the metal (Hg) detected in this study. The linearity of the calibration curves was excellent (r2>0.998) at various concentrated levels. The limits of detection (LoD) value in feed was 0.007 mg/Kg and the limit of quantification (LoQ) value in feed sample was found 0.023 mg/Kg. The values of instrumental detection limit (IDL) and instrument quantification limit (IQL) were 0.045(μg/l), and 0.15(μg/l), respectively. The recovery (%) found for the metal was 92.29 %. The overall CV% of repeatability and reproducibility ranged from 3.27 % to 5.92 %. The value ranges from 12 to 16 was observed for the measurement uncertainty (%) of Hg in this study. The proposed validation criteria indicate that it is a reliable method that can be used easily for the routine analysis of toxic metal (Hg) content in poultry feed sample.
Patient-Controlled Sedation by Non-Anaesthesiologists during Flexible Bronchoscopy: A One-Year Experience Regarding Safety, Feasibility and Costs
Authors:   Department of Anaesthesia and Intensive Care, County Council of Östergötland, Linköping, Sweden, B Grossmann , A Nilsson ,   Department of Anaesthesia and Intensive Care, County Council of Östergötland, Linköping, Sweden
Published: January 2023

Background: Patient-controlled sedation (PCS) is an efficient and costsaving method for sedation during flexible bronchoscopy (FB) in the presence of anaesthetic staff, but no data is available for PCS in a non-anaesthesiologist environment. Methods: This descriptive study describes PCS with propofol in a non-anaesthesiologist setup during outpatient FB procedures, including transbronchial biopsy, transbronchial needle aspiration, cryotherapy/biopsy and/or multistation endobronchial ultrasound, and endoscopic ultrasound with bronchoscope. Results: 287 procedures were completed. The median (range) duration for the procedures was 45 (10-105) minutes. The median (range) total propofol dose administered was 201 (55-570) mg, and 61 procedures (21%) required bolus doses of alfentanil. Desaturation occurred during 21% of the procedures and was resolved spontaneously (59%) or by using a jaw thrust (41%). No evidence was found that alfentanil contributed to desaturation (p=0.081). Inconsistent results were shown regarding the impact of alfentanil on the reduction of cough. The post-procedural assessment revealed high score of satisfaction and feasibility. 3 (1%) procedures were cancelled due to insufficient sedation. No prolonged recovery with need of overnight stay was reported. The direct costs for sedation were 180 USD/procedure. Conclusion: PCS with propofol and the presence of trained nonanaesthesiologists during outpatient FB has shown to result in high procedure feasibility and satisfaction without compromising patient safety or increasing the risk for unhandled respiratory adverse events. The method reduces costs for sedation and offers the possibility to increase patient turn over due to no prolonged recovery.
Post-functionalization and Mechanical Properties of Poly(lactide-cyclohexadiene oxide) Block Copolymers
Authors: Dai Ruxi , Deng Shijie , Peng Zihang , Pei Qibing , Diaconescu Paula
Published: January 2023

A series of lactide (LA) and cyclohexadiene oxide (CHDO) multiblock copolymers was synthesized using a redox switchable complex, (salfen)Zr(OiPr)2 (salfen = N,N’-bis(2,4-di-tert-butylphenoxy)-1,1’-ferrocenediimine), with LA being polymerized by the reduced state, while CHDO was polymerized by the oxidized state of the catalyst. Diblock (PCHDO-PLA) and triblock (PLA-PCHDO-PLA and PCHDO-PLA-PCHDO) copolymers were prepared, and all the copolymers were post-functionalized using a thiol-ene click reaction. Dynamic mechanical analysis showed that both triblock copolymers have a better elasticity than the diblock copolymer, and all the functionalized copolymers have a better elasticity than the corresponding non-functionalized copolymers.
How to deal with future possible coronavirus: hints from the analysis of the interaction between potential inhibitors with 3C-Like protease via molecular docking
Authors: Meng Tao , Qiu Yinong , Li Fangya , Zhang Jianyu
Published: January 2023

The COVID-19 pandemic has resulted in millions of infections and deaths. However, there is still a lack of broad-spectrum effective and safe anti-CoV drugs. 3CL protease is one of the promising targets for the development of anti-CoV drugs. In this study, we explored the binding effects of 36 potential inhibitors with five hu-man coronavirus 3CL proteases (SARS-CoV-2, MERS-CoV, SARS-CoV, HCoV-HKU1 and HCoV-229E) via molecular docking using SwissDock. The correlation study demonstrated that small molecule inhibitors with higher molecular weight were likely to be more effective. Based on the fact that SARS-CoV-2 3CLpro had the poorest binding tendency and affinity with ligands, we predicted that the CoVs will become more and more difficult to overcome as they evolve. The interaction analysis showed that the lethal human coronavirus 3CL proteases had higher hydrogen bonding interaction propensity on Glu16X. These findings offer interesting perspectives for future drug design strategies against human coronavirus.
IMPACT OF PINCHING ON GROWTH AND YIELD OF MARIGOLD (Tagetes erecta L.)
Authors: Joshi Dipesh , Rizal Govinda , Awasthi Prakash
Published: January 2023

Marigold, a member of the Asteraceae family, is a popular ornamental plant grown throughout the world, including Nepal. The color and size of the flowers on marigold plants vary. Marigold plants can reach a height of 5 feet, but pinching procedures can lower this, allowing the intercultural operation to continue. Tagetes erecta L. is one of the most well-known marigold varieties in Nepal. Pinching is a technique for breaking apical dominance and redirecting energy to increase blossom production. Different experiments including treatments like no pinch, single pinch, and double pinches were reviewed to evaluate the effect of pinching on the growth and yield of marigolds. The effect of pinching on marigold growth and yield was investigated by comparing parameters such as plant height, number of branches per plant, number of flowers per plant, and flower size of pinched and unpinched (healthy) plants. The height of the unpinched plant was found to be 25% higher than that of the pinched. When plants are pinched, their apical dominance is broken, which encourages the plant to generate lateral branches and become bushy Because the majority of the nutrition is dislocated from the apical region of the plant when it is pinched; no pinched plants have fewer branches than pinched plants. Pinching stimulates cell division, cell size, leaf area, and photosynthetic compound production, which affects branch formation and, as a result, flower production. According to the results from various trials, double pinching resulted in the highest increase in plant height, number of branches, number of flowers per plant, and bloom size when compared to no pinching.
ASSESSMENT OF AGRO-ECOLOGICAL CHANGES IN THE KASSENA-NANKANA DISTRICT(S) AS A RESULT OF THE CONSTRUCTION OF THE TONO RESERVOIR USING MULTI-TEMPORAL IMAGERY
Authors: Ampofo Steve , S. Coffie Ernestine , M. Kusibu Michael
Published: January 2023

Land Use / Land Cover (LULC) changes has been progressive across the globe, causing the alteration and shifting of various land use/land cover features. These changes are caused by natural factors such as extreme environmental conditions, earthquakes, volcanic eruption, flooding and also human factors including agricultural expansion, urban and industrial development of infrastructure. The study combined spatial time series satellite data and field observations to observe the changes which have occurred in the land cover mapping between 1999 and 2007. Land cover features were categorized into Vegetation, Crop/farmland, Settlement, Bare land and Water body. Satellite imagery for the intervening period was used to assess the changes in LULC. LULC classes of Settlements and Bare land recorded an increase of 3.21%, and 33.1%, whereas Vegetation, Crop/farmland and Water decreased by 1.8%, 33% and 2.1% respectively. It was observed that the mean conversional change between 1999 and 2007 was 2148.55 hectares. A total land size of 9297.79 hectares did not undergo any change; conversion into Water body was 417.62 hectares, 7688.56 hectares was changed into Crop/farmland, 1137.76 hectares into Settlement, 337.17 hectares into Bare land, and 1161.65 hectares into Vegetation. It was also observed that the sharp increase in Settlement is as a result of rapid population growth and expansion of infrastructure.
STATUS OF AIR QUALITY AND NOISE LEVEL WITH ASSOCIATED HEALTH RISK VICINITY TO SHIPBREAKING YARDS OF BANGLADESH
Authors: Hossen Md. Arif , Ruva Israt Jahan , Hassan Masum Md. Mehedi , Barua Prabal
Published: January 2023

Shipbreaking industry has turned out to be dominant sector in Bangladesh without considering the environmental issues. However, to date, extremely limited studies have been performed to monitor the air and noise level around shipbreaking sites of Bangladesh. This study is conducted to assess the air and noise level with associated health risk vicinity to selected shipbreaking areas of the country. Herein, data on various air pollutants, noise level, and meteorological factors were collected from six prominent shipbreaking yards in Chattogram. Findings of the research work revealed that some air quality parameters and noise level adjacent to shipbreaking areas are exceeded the permissible level set by the WHO. The values of Air Quality Index (AQI) is found in the unhealthy category for human health perspective. The average noise level was also recorded beyond the permissible limit in every sampling sites, following descending order: S3 > S4 > S5 > S6 > S1 > S2. From the statistical analysis, the authors explored that there are significant correlation with poor to strong (0.0.026 to 0.97) among the climatic parameters and air pollutants. Both particulate matters and AQI demonstrate a moderate correlation with the meteorological parameters (humidity and wind speed), and gaseous air pollutants (CO2 and TVOC) also have considerable correlations. The moderate correlation between AQI and noise level is also observed in this study. The authors recommended for effective control actions to alleviate the detrimental environmental pollution arises due to the consequences of shipbreaking activities for ensuring health safety of workers.
EVOLUCIÓN DE LA VIOLENCIA SEGÚN EL GÉNERO EN EL PERÚ, 2017-2021
Authors: García Tuesta Rocío del Pilar , Sánchez Pantaleón Alex Javier , Valdiviezo Sir Víctor Manuel
Published: January 2023

El acontecimiento de violencia cada vez preocupa más en todos los países y sin duda el Perú no es la excepción. Esta investigación tiene como objetivo describir la evolución de la violencia del género femenino en comparación con el masculino. La metodología empleada fue descriptiva y se utilizó como población muestral las series anuales de violencia registrada durante el periodo 2017-2021 reportados por el Instituto Nacional de Estadística e Informática (INEI). La técnica que se empleó fue la de análisis documental y el instrumento fue una ficha de registro, usando los tipos de violencia por géneros. Los resultados demuestran que la mayor parte de víctimas de violencia son las mujeres (85.09%), pues las cifras son más elevadas en comparación con la violencia que sufren los varones (14.91%). En conclusión, de acuerdo al tipo de violencia que con mayor frecuencia sufren las mujeres son: la sexual (87.54%); física (71.13%); psicológica (66.87%) y por último la violencia económica (46. 65%).Por lo tanto es necesario fortalecer las políticas de protección al género femenino contra cualquier tipo de violencia.
PARTICIPACIÓN LABORAL DE LA MUJER EN LA REGIÓN AMAZONAS, PERÚ 2010-2020
Authors: Manosalva Cruz Iris Jhaneth , García Baldera Karen Melany , Grandez Chappa Sandro Hamer , Chávez Arroyo Franklin Omar Zavaleta
Published: January 2023

La investigación tuvo como objetivo determinar el nivel de participación de las mujeres en el mercado laboral en comparación a los hombres en la región Amazonas. La investigación es descriptiva con una población constituida por series anuales de la fuerza laboral femenina y masculina de la región Amazonas, 2010-2020. La técnica utilizada fue el análisis documental y el instrumento la ficha de registro. Los resultados indican que la Población Económicamente Activa (PEA) Femenina ocupada fue en promedio 40.91% mientras que los hombres 59.08%; la tasa de actividad en mujeres es menor en 18.1%, evidenciando una baja representación, en cuanto al empleo formal e informal es de 1.7% y 3% respectivamente, los subempleados en su mayoría son mujeres con un 78.4%; en el sector primario, secundario y terciario la participación es de 52.2%, 43.8% y 4% respectivamente. Se concluye que la PEA femenina tuvo un nivel medio de participación, una alta tasa de actividad y ocupación en el empleo informal; la tasa de mujeres ocupadas adecuadamente empleadas es baja y la mayoría están subempleadas. Finalmente, la Población ocupada del sector primario y terciario presentan un nivel medio, y el secundario un nivel bajo de participación.
Peer Relations and Positive Development in Students with Visual Impairment
Authors: Jaleel Faiza , Kanwal Asma , Aasma
Published: January 2023

Purpose: Peer relations is very important to facilitate social development of students. Peer relations also enhance other aspects i.e. societal, emotive and educational capabilities. Peers help each other to develop positively and groom their personality. This study aimed to explore the relationship between peer relations and positive development in students with visual impairment.  Students with visual impairment require more understanding peers to adjust in their classroom, school and social setting. Major objective of the study was to identify relationship between peer relation and positive development in students with visual impairment.

Design/Methodology/Approach: Correlational research design was used in this study. Students with age range of 15 to 30 years were selected as a population of the study. Sample of the study was selected by using purposive sampling technique. Sample of 80 students with visual impairment was drawn from Punjab province including different educational institutions. Inferential statistical techniques were used to analyze the data.

Findings: It was concluded that peer relation was a predictor of positive development for students with visual impairment.

Implications/Originality/Value: This study will help to understand the importance of peer relation for the facilitation of positive development in students with visual impairment.
Enhancing the Dining Experience through Emotional Tableware Design
Authors: Nazri Haslinda Md. , Zali Madya Dr. Abdul Aziz B. Zalay , Ibrahim Noor Aileen
Published: January 2023

Objective: At present, the tableware used represents the image of the restaurant as it is able to create a visual attraction or known as ‘visual synchronisation’ with food. Emotional tableware design is able to influence the behaviour of people through the dining experience. This is due to the attractive visual design of the tableware which will have an indirect influence on the aroma and taste of the cuisine being presented as well as the surrounding ambience. Methodology: The three levels of design theory which include visceral, behavioural and reflective play a significant role in providing an impact or having a great influence on the fine dining experience. Consequently, amplifying the integration of senses, interaction and response towards emotions.

Findings: An emotional tableware design will lead to a more positive experience. This positive experience will elevate positive emotions through its functionality, convenience and satisfaction. A tableware designer is able to evoke such emotions as the emotional design has no specific rules or clear protocol. The positive experience that is emotionally inspired will lead to a better life experience or make life more interesting. Implications: The use of an emotional tableware design by chefs in fine dining has elevated the dining experience to a whole new level which amplifies the deep impact that this concept has on the world of tableware design.
Effect of COVID-19 Vaccine on Menstrual Cycles
Authors: Abdulaal Nada Abdulfattah , Kamal Nahid
Published: January 2023

Background: A worldwide increase in menstrual abnormalities was reported post Coronavirus disease (COVID-19) vaccinations. The study aimed to investigate the prevalence and impact of the menstrual abnormalities post COVID-19 vaccinations in Bahrain. The study also looked at the variations after first, second and third dose of vaccination. Methods: The survey was sent to the participants who had received the COVID-19 vaccinations (n=1000) via social media as well as printed copies; 343 responses were received. Participants who had a history of irregular menstruation prior to COVID-19, were on hormonal or non-hormonal medications, gynaecological and non-gynaecological diseases were excluded from the study. Results: The findings indicated that 62.5% of the participants reported menstrual abnormalities after COVID-19 vaccinations manifested as changes in frequency, length and quantity of menstruation. Majority of the participants had Sinopharm for their first and second doses (62.8% and 58.5% respectively) while majority of the participants had Pfizer as third or booster dose (88.4%); however, was no significant effect of the type of vaccine on the menstrual changes. 46.8% of the participants reported that their daily life activities were affected and about 5.8 % participants were prescribed medications to regulate their menstruation. Conclusion: The study indicated that there is a temporary effect of COVID-19 vaccination on menstrual cycle about which the women needs to be counselled and informed. Keywords: COVID-19 vaccination, menstrual abnormality, variation in menstruation
Pengaruh Persepsi Profesi Guru, Efikasi Diri, Lingkungan Keluarga, Dan Teman Sebaya Terhadap Minat Menjadi Guru Mahasiswa Prodi Pendidikan Akuntansi UNESA
Authors: Tifani Savira Sarah , Wahjudi Eko
Published: January 2023

A good education is a bridge to make a nation great and advanced. In other words, the teacher has a big role in it all. Teachers have a big role in realizing the success of education. This relates to education students who have been prepared to become teachers in the future. However, not all students set future goals to become teachers. Several causes can influence interest in becoming a teacher, including student perceptions of the teaching profession, student self-efficacy, family environment, and peers. This study aims to determine the effect of perceptions of the teaching profession, self-efficacy, family environment, and peers on students' interest in becoming teachers. This research belongs to the category of quantitative research. The research population used was students of the 2018 Accounting Education Study Program, Surabaya State University as many as 60 students with a sampling technique, namely saturated sampling. The method of data collection is done through a questionnaire. Based on the test results, it is known that 1) The perception of the teaching profession has no significant effect on student interest in becoming a teacher, 2) Self-efficacy has no significant effect on student interest in becoming a teacher, 3) Family environment has a significant effect on student interest in becoming a teacher, 4) Peers have a significant effect on students' interest in becoming teachers, and 5) Perceptions of the teaching profession, self-efficacy, family environment, and peers simultaneously have a significant effect on students' interest in becoming teachers.
Efek Motivasi Investasi Sebagai Moderator Pengaruh Pengetahuan Investasi Dan Perilaku Keuangan Terhadap Minat Investasi
Authors: Nesia Satya , Widayati Irin
Published: January 2023

The development of investment in Indonesia has increased during the post-Covid 19 economic recovery period. The public is realizing the importance of investing and the benefits, including students are also aware of this. The factors that encourage students to invest are investment knowledge, financial behavior, and investment motivation. This study aim's to investigate the effect of investment motivation as a moderator of the influence of investment knowledge and finance behavior. The population used is 2015-2019 accounting education students who are still students with a total of 145 students. The sample used in the study was determined by the solving formula. While the sampling technique used is proportionate stratified random sampling. Data collection was carried out online in the form of a questionnaire in the form of a Google form. Then the data were analyzed using descriptive statistical methods then hypothesis testing was carried out using multiple linear regression analysis and moderation regression analyst the application used was SPSS version 26. Obtained from the results of the analysis of investment knowledge and financial behavior were able to produce a positive and significant influence on investment interest. Then investment motivation can moderate the effect of investment knowledge on investment interest.
Peran Motivasi Belajar Dalam Memediasi Lingkungan Keluarga Dan Kemandirian Belajar Terhadap Hasil Belajar Akuntansi Keuangan Menengah 1
Authors: Lestari Dwi Rahma , Listiadi Agung
Published: January 2023

This research aims to analyze the effect of learning motivation as a mediation variable between family environment and independent learning on intermediate Financial Accounting I learning Outcomes. This study uses quantitative approach. The sampling techniques using purposive sampling so that 112 students were obtained as respondents. Data collection techniques through questionnaires and documentation. Data were analyzed using classical  assumption  test, regression  analysis,  path  analysis  and  sobel  test . The findings in this study show that (1) family environment have significant direct impact on intermediate Financial Accounting learning Outcomes. (2) Independent learning have significant direct impact on intermediate Financial Accounting learning Outcomes. (3) learning motivation have significant direct impact on intermediate Financial Accounting learning Outcomes. (4) family environment have significant direct impact on learning motivation. (5) Independent learning have significant direct impact on learning motivation. (6) Learning motivation cannot mediate family environment on intermediate Financial Accounting learning Outcomes. (7) Learning motivation mediate independent learning on intermediate Financial Accounting learning Outcomes.
Triple Entry Bookkeeping di Era Teknologi Blockchain: Suatu Kajian Literatur
Authors: Ahmad Arisona , Wahyuni Ika Sri , Istiqomah Lailatul , Tiyas Eka Wulan Wahyuning
Published: January 2023

The financial industry in the era of technological development began to be supported by Blockchain technology. Blockchain is a new idea in the financial industry as a solution to solve the problem of digital money (cryptocurrency).  Transactions recorded in the blockchain will be permanently stored so that they cannot be manipulated and provide a higher level of security. Blockchain technology supports the development of triple entry bookkeeping which is a configuration of the development of the double entry bookkeeping system. This research uses qualitative proximity to the library research method.  The data collected comes from indexed journals on Google Scholar, Science and Technology (Sinta), Directory of Open Access Journals (DOAJ), books and other literature which will then be analyzed and set forth in the form of written words.The results of this study show that Triple Entry Bookkeeping in the Blockchain era has many advantages as a form of development of Double Entry Bookkeeping, namely providing information about budgets, automatic transaction validation, automatic public ledger, increasing openness & trust, and solving fraud. In Indonesia itself, blockchain implementation in the field of accounting has been widely carried out, such as on the Online Pajak platform, Bank BCA, PT Pos Indonesia, and other commercial companies listed on the Indonesian Blockchain Association (ABI). The implementation of the triple entry bookkeeping system is still not ready to be implemented by medium-sized entities and MSMEs due to the high costs required, the lack of understanding of professional accountants regarding technology and entities that feel they still do not need a triple entry bookkeeping system. Therefore, support from all parties is needed so that this research can develop and not only become a concept but can be implemented in the financial industry.
ANALYSIS OF THE INFLUENCE OF THE SYNCHRONOUS SUPPLY METHOD ON THE PERFORMANCE OF THE ASSEMBLY LINES
Authors:   University of Pitesti, GAVRILUȚĂ Ana Cornelia
Published: January 2023

Today, businesses must deal with very demanding customers and fierce competition. To be able to face all these demands, they must have a competitive production system. Until now, research has focused on methods to improve production, but today companies are beginning to realize that an improvement in internal logistics is equally an alternative to attract a new advantage on their side. For this reason, the main objective of the research in this article is to study the influence of the synchronous workstation supply method. On the performance of assembly lines. With the help of experience plans, the influence of certain input data (daily demand and diversity) considered at certain levels on the total cost was obtained. The values of these functions (response variables) that correspond to the factors and levels imposed by the experience plan, were obtained with the help of process simulation in the ARENA program. The analysis of the cost pointed out the fact synchronous supply methos have a significant influence on assembly lines performance.
Kentlerde Sessiz/Sakin Alanların Önemi Ve Eskişehir Kurşunlu Cami ve Külliyesi Bahçesinin İşitsel Peyzaj Yaklaşımıyla Değerlendirilmesi
Authors: AKIN GÜLER Gülşen , ÖZÇEVİK BİLEN Aslı
Published: January 2023

Hızla büyüyen, kalabalıklaşan, karmaşıklaşan ve daha gürültülü hale gelen kentlerde yaşam kalitesi giderek düşmekte ve kentte yaşayan insanlar sessiz/sakin bir ortamda dinlenme, rahatlama ve rehabilite olma ihtiyacı hissetmektedir. Bu anlamda kentsel bölgelerdeki park, bahçe, avlu vb. açık alanlar sessiz/sakin alan olarak, bu ihtiyacın karşılanması için kullanılabilecek öneme sahip mekanlardır. Bu tür yerlere örnek bir alan olarak Eskişehir Kurşunlu Camii ve Külliyesi bahçesi bu çalışmada konu edilmiştir. Eskişehir Odunpazarı Kentsel Sit Alanı içerisinde bulunan ve bir Osmanlı Dönemi yapı grubu olan külliye, tarihi değeri ve turistik kullanımı ile ön plana çıksa da külliyeyi oluşturan binaların arasında kalan yeşil alan, çevresine göre sessiz/sakin bir yer olma potansiyeline sahiptir. Bu bağlamda bahçe, alana sessizlik/sakinlik niteliği kazandıran özellikleri açısından işitsel peyzaj yaklaşımıyla alan çalışması üzerinden incelenerek sessiz/sakin alan olma potansiyeli değerlendirilmiş, sessizlik/sakinlik algısını etkileyen faktörler (akustik özellikler, mekânsal özelikler, işlev) belirlenmiştir. Alan çalışmasında akustik ölçüm ve anket yapılmıştır.
Akustik ölçüm sonuçlarına göre alandaki ses basınç düzeyi (LAeq) kabul edilebilir düzeyin (55 dB’in) altındadır. Anket sonuçlarına göre ise beklenene paralel olarak alan, çoğunluk tarafından sessiz/sakin olarak değerlendirilmiştir. Alanda sessizlik/sakinlik algısını etkileyen faktörler alan özelliklerine göre; alanda su sesinin, kuş seslerinin ve dini seslerin duyulması; ses kaynağı sayısının ve çeşidinin az olması; yetişkin ağaçların bulunması, alanın tarihi ve kültürel değere sahip olması şeklinde ifade edilmiştir. Sonuç olarak Kurşunlu Camii ve Külliyesi bahçesinin sessiz/sakin alan olarak kullanılabileceği ve dolayısıyla farklı kentsel bölgelerde bu alan ile benzer özelliklere sahip açık alanların da ergonomik kent koşullarının oluşturulmasına katkı sağlayan alanlar olarak değerlendirilebileceği ortaya konulmuştur
Osteocalcin: A new phenomenon for type 2 diabetes and obesity
Authors: Kocak Tevfik , Acar Tek Nilufer
Published: January 2023

Objectives: The molecular biology revolution has emerged with the determination that bone tissue is an endocrine organ that regulates many physiological processes, and osteocalcin (OCN), an osteoblast-derived protein that provides endocrine control, is a hormone that regulates glucose and energy homeostasis. By controlling gene expression in β-cells and adipocytes, OCN improves glucose intolerance, obesity, and insulin expression. In addition, OCN stimulates the secretion of adiponectin, a molecule that increases fatty acid oxidation and insulin secretion and sensitivity in adipose tissue and reduces adipose tissue accumulation. Recent research suggests that serum OCN increases the expression of peroxisome proliferator-activated receptor gamma coactivator-1α (PGC-1α) and uncoupling protein-1 (UCP1) genes, which play a role in thermogenesis in brown adipose tissue, it also affects insulin sensitivity by increasing adiponectin expression in white adipose tissue. OCN the target gene of insulin, and resting energy expenditure and mitochondrial biogenesis. With all these effects, OCN is a protein that has recently been found to be associated with diabetes and obesity components.

Conclusions: This review aims to present an overview of understanding the interaction of OCN produced by osteoblasts with insulin, glucose metabolism, adipose tissue, skeletal and muscle tissue, and appetite metabolism in understanding the endocrine functions of bone. In addition, it was conducted to examine the role of OCN in energy metabolism and to evaluate the relationship of energy metabolism pathways affected by OCN with non-communicable chronic diseases such as type 2 diabetes mellitus and obesity.
Assessing STEM career interest among secondary students: A Rasch model measurement analysis
Authors: Ardianto Didit , Rubini Bibin , Pursitasari Indarini Dwi
Published: January 2023

This study aims to validate the STEM career interest survey (STEM-CIS) using Rasch model approach. This study involved 572 junior high school students with 105 seventh-grade students, 124 eighth-grade students, and 343 ninth-grade students. The data were analyzed using Rasch model, which included analysis of item validity and reliability, item fit order, Wright map analysis, and DIF analysis. The results present that the STEM-CIS items show good measurement skills and have logical predictive abilities. STEM-CIS items also have very good reliability, and most items meet the item fit order test criteria. However, there are some items from the STEM-CIS that still detect gender and grade level bias. This study provides evidence that the STEM-CIS items are tested to be valid and reliable to measure students’ interest. In addition, this study also provides evidence that some STEM-CIS items still detect gender and grade level bias.
IoT-based smart infant baby cradle using IR IP-camera
Authors: Ibrar Ahmad  , Syed Jabir Hussain  , Safeer Ullah  , Waqas Ali Shah  , Hamid Ali  , Umar Waqar  , Shah Fahad
Published: January 2023

With the evolution of the internet of things and headway technologies like android phones and sensors every single thing got coupled and get controlled through the internet distantly, but at the same time the number of family member workers is also incremented. infant baby needs parental aid 24/7 to monitor different actions and check different parameters distantly but it is impractical, especially for those Parents/Caretakers who work outside of the home. So, there is a need for a system through which Parents/Caretaker can aid their infant baby and see infant babies’ activities distantly in real time about different parameters and conditions of the infant baby. The proposed system is a smart infant Baby Cradle using IoT Technology that sends an alert notification to the Parent/Caretaker. In the proposed system IR IP-Camera is used to seize an infant baby in the real environment even at night. The proposed system is able to sense an infant baby’s scream using a Microphone Module for 10 seconds, the temperature of the infant’s environment, sense urine in meters ultrasonic sensor, automate the opening and closing of mosquitoes’ net to sense mosquitoes and other harmful parasites using PIR sensor, infant baby Mass using weighting Scale, automatic fan, toys and music to entertain infant baby. The power bank is used to aid infant baby’s in case of lack of electricity. Finally, all these sensors and components are physically connected through Arduino AT Mega 2560. When sensors sense then it updates data onto the database server and notifies her/his Parent/Caretaker using HC-05 Blue-tooth and GSM SIM900A-D57 Module. The proposed system is able to keep all recorded history for one month.
Em nome de Allah e de Orixá: conexões entre Lagos e Rio de Janeiro nos anos de 1890-1930
Authors: Guimarães Thamires
Published: January 2023

No Rio de Janeiro, de início do século XX, africanos da nação mina, minoria na cidade, eram conhecidos por professarem tanto o Candomblé quanto a fé muçulmana. Este artigo segue os passos de uma figura central para o grupo mina da cidade, Emanuel Ojô, que liderava e financiava as viagens de seus conterrâneos da cidade de Lagos para o Rio de Janeiro, capital da República brasileira do período, ensinando a religião muçulmana e a inserção no mercado de “feitiços”, levando em consideração as questões políticas tanto de Lagos, que passava pelo chamado “Renascimento/Nacionalismo Yorubá”, quanto do Rio de Janeiro com as transformações sociais da Belle Époque e a perseguição às religiosidades de origem africanas.
O negacionismo político-científico no cotidiano de trabalho da categoria médica: uma análise com base na história oral
Authors: Aparecido de Barra e Lopes Edmar
Published: January 2023

Este artigo tem como objetivo compreender por que se tornou recorrente no cotidiano profissional de médicos e médicas que atendiam a pacientes com COVID-19, práticas e posições políticas afinadas com o negacionismo político e científico sob a forma da defesa e uso do tratamento precoce. A metodologia utilizada foi a produção de entrevistas com médicos e médicas com base na história oral, além de literatura especializada e fontes primárias escritas, como jornais e documentos institucionais. Ressalta-se que a realização dos referidos depoimentos teve como pano de fundo um dramático momento da pandemia caracterizado pelo não início da campanha de vacinação contra o patógeno em tela e pelo consequente crescimento descontrolado do número de casos e óbitos. Os resultados da pesquisa permitiram concluir que, em tal cenário, expressivos segmentos da categoria médica, enquanto elite profissional no mercado de trabalho em nível nacional, defenderam uma agenda contracivilizatória de braços dados com valores e bandeiras neoconservadoras associadas ao bolsonarismo. Neste sentido, alguns segmentos da categoria médica contribuíram para o estabelecimento de uma ruptura histórica com um projeto de modernidade fundado na aliança entre Estado e ciência que ajudou a construir no final do século XIX.
Os transportes na formação urbana das periferias: a luta dos moradores de São Mateus pela circulação na cidade de São Paulo
Authors: José de Sousa Adriano
Published: January 2023

O papel dos transportes na urbanização dos subúrbios e das periferias paulistanas remonta, respectivamente, ao final do século XIX e à segunda metade do século XX. Em ambos os casos, a atuação dos moradores como agentes ativos desses processos é decisiva para entender seus projetos de cidade e a necessidade de articulação dos seus territórios com a cidade edificada. Neste artigo, tratamos dessas relações que ocorreram em São Mateus, atualmente Subprefeitura do extremo leste da cidade de São Paulo, entre os anos de 1950 e 1980, demonstrando como as mobilizações sociais pressionaram e construíram parcela significativa do município em suas periferias.
Identifikasi Minat Remaja Lamongan terhadap Perbankan Syariah
Authors: Aulan Zamrotin Aulan Nisak
Published: January 2023

Berbeda dengan perbankan konvensional yang hanya mengenal bunga. Perbankan Syariah menganut sistem bagi hasil dalam bisnis prosesnya.Perkembangan Bank Syariah menjadi lebih massif semenjak tiga bank syariah (BNI Syariah, Bank Syariah mandiri, BRI Syariah) digabung menjadi satu dengan nama Bank Syariah Indonesia (BSI). Namun apakah hal tersebut menumbuhkan minat remaja untuk menabung di Bank Syariah. Penelitian ini bertujuan mengetahui minat remaja lamonganterhadap perbankan syariah. Metode yang digunakan adalah Deskriptif Kualitatif, dengan pengumpulan data melalui google form, remaja dengan usia 17-20 tahun.  Hasil penelitian ini menunjukkan bahwa remaja Lamongan lebih memilih bank konvensional karena beberapa hal yaitu referensi orang-orang terdekat, lokasi yang lebih terjangkau, dan tingkat literasi keuangan syariah yang rendah.
Разработка и валидация методики идентификации и количественного определения остаточных органических растворителей в фармацевтических субстанциях пептидной структуры
Authors: Дуденкова М. , Грушевская Л. , Сергеева М. , Гаевая Л. , Денисенко Е. , Минаев С.
Published: January 2023

Разработана унифицированная методика идентификации и количественного определения остаточных органических растворителей в фармацевтических субстанциях, представляющих собой короткие пептиды, методом ГЖХ со статической парофазной экстракцией. Разделение проведено на капиллярной колонке CP-WAX 52 CB, 50 м ? 0,32 мм, 1,2 мкм (Agilent). Разработанные условия хроматографирования позволили эффективно разделить органические растворители, наиболее часто используемые в процессе синтеза и очистки фармацевтических субстанций: этанол, метанол, ацетон, этилацетат, диэтиловый эфир, бензол, гексан, пентан, метиленхлорид, тетрахлорметан, толуол, диметилформамид, а также пиридин, хлороформ и 1,4-диоксан. Валидация методики показала её специфичность, линейность, правильность и прецизионность.
Фармакокинетическая оценка лекарственной формы соединения IPAC-2015
Authors: Жердев В. , Колыванов Г. , Литвин А. , Шевченко Р. , Грибакина О. , Бочков П. , Григорьев В.
Published: January 2023

На кроликах проведено открытое фармакокинетическое исследование после однократного, перекрестного введения капсул и субстанции IPAC-2015 в дозе 30 мг. Рассчитаны следующие фармакокинетические параметры: максимальная концентрация IPAC-2015 в плазме крови, время ее наступления, площадь под фармакокинетической кривой, период полувыведения IPAC-2015, относительная биодоступность. Концентрации IPAC-2015 определяли в плазме крови с использованием метода ВЭЖХ с масс-спектрометрическим детектированием (тип «ионная ловушка») по дочернему иону с отношением массы к заряду m/z = 163, полученного изолированием и фрагментацией нативного молекулярного иона с отношением массы к заряду m/z = 425 (что соответствует протонированному молекулярному иону) IPAC-2015. Относительная биодоступность таблеток IPAC-2015 в сравнении с субстанцией составила (89,21 ± 5,04) %.
Влияние цикориевой и хлорогеновой кислот из Cichorium intybus L. на активность цитохрома Р450 и глутатионтрансферазы
Authors: Лупанова И. , Мизина П. , Ионов Н. , Поройков В. , Хлебников А. , Мартынчик И.
Published: January 2023

Растительные БАВ могут действовать как лиганды для рецепторов, регулирующих экспрессию цитохрома Р450 (CYP450) и тем самым изменять его активность, что, в свою очередь, может влиять на терапевтический эффект лекарственных средств, эндогенных гормонов и т.д. В исследовании спрогнозированы гепатопротекторная активность цикориевой и хлорогеновой кислот, выделенных из надземной части травы цикория обыкновенного (Cichorium intybus L.), а также их взаимодействие с различными изоформами CYP и GST (Ра > 0,5). Полученные экспериментальные данные с применением специфических ферментных биотест-систем in vitro соответствуют результатам компьютерного прогноза in silico и показывают, что внесение оксикоричных кислот в инкубационную среду приводит к повышению скорости CYP450, в то время как препарат сравнения Силимар® оказывал большее влияние на глутатионтрансферазу. С помощью молекулярного докинга (программа Molegro Virtual Docker 6.0) продемонстрировано, что цикориевая и хлорогеновая кислоты могут связываться с активными центрами CYP450 (CYP3A4) и глутатионтрансферазы (GST1) за счет водородных связей, с аминокислотными остатками. В связи с этим при приёме препаратов травы цикория обыкновенного необходимо учитывать данное взаимодействие для предотвращения лекарственного взаимодействия с другими фармакотерапевтическими лекарственными средствами, метаболизирующимися CYP3A4 для получения положительных эффектов и избегания вредных нежелательных лекарственных реакций.