bluuebunny/crossref_metadata_2025 huggingface dataset:
Secondary Prevention in Patients with Ischemic Heart Disease after Myocardial Revascularization
Authors:   Federal State Budgetary Educational Institution of Higher Education “North-Western State Medical University named after I.I. Mechnikov” of the Ministry of Health of the Russian Federation, Boldueva S.A. ,   St. Petersburg, Russian Federation, Evdokimov D.S. ,   Federal State Budgetary Educational Institution of Higher Education “North-Western State Medical University named after I.I. Mechnikov” of the Ministry of Health of the Russian Federation; St. Petersburg, Russian Federation, Guzeva V.M. ,   State Budgetary Healthcare Institution “Leningrad Regional Clinical Hospital”; St. Petersburg, Russian Federation
Published: October 2022

Objective of the Review: Help the doctor in a conversation with the patient to additionally motivate him to follow the recommendations for secondary prevention in the period after myocardial revascularization. Key points. The article discusses the main risk factors that contribute to the progression of cardiovascular diseases (overweight and obesity, smoking, physical inactivity, depression and anxiety, dyslipidemia, diabetes mellitus, arterial hypertension), as well as various methods of secondary prevention after myocardial revascularization, based on modern data of evidence-based medicine: weight loss, regular physical training, psychopharmacotherapy, high adherence to drug therapy. Conclusion. Conducting secondary prevention measures is extremely important for patients after myocardial revascularization, since the progression of coronary artery atherosclerosis continues after surgery. Therefore, in the postoperative period, the likelihood of developing cardiovascular events, in particular, early periprocedural myocardial infarction, stent thrombosis, and late restenosis, remains. Optimal drug and non-drug preventive measures improve the quality of life and improve the prognosis in this category of patients. Keywords: ischemic heart disease, cardiovascular disease, secondary prevention, myocardial revascularization, healthy lifestyle.
Assessment of Retrospective Analysis Results for the Use of Leflunomide in Chronic Sarcoidosis
Authors:   Kazan State Medical University of the Ministry of Health of the Russian Federation, Vizel A.A. ,   Kazan, Russian Federation, Vizel I.Yu. ,   Kazan State Medical University of the Ministry of Health of the Russian Federation; Kazan, Russian Federation, Shakirova G.R. ,   Kazan State Medical University of the Ministry of Health of the Russian Federation; Kazan, Russian Federation,   National Clinical Hospital of the Ministry of Health of the Republic of Tatarstan; Kazan, Russian Federation
Published: October 2022

Study Objective: To assess the efficacy and safety of the use of leflunomide (LF) in chronic present and/or refractory sarcoidosis. Study Design: Retrospective observational non-interventional analysis. Materials and Methods. We studied the use of LF (20 mg daily) in 15 out of 1470 (1.0%) patients included into the State Sarcoidosis Clinical Database. The group included 11 female and 4 male patients aged 30 to 60 years old. 2 patients had X-ray stage I disease, 11 patients had stage II, 1 patient had stage III, and 1 patient had stage IV. All patients had histologically-proven diagnosis. We assessed the clinical condition of the patients as well as laboratory and functional data. We used SPSS-18 for statistical processing. Study Results. Stable and improved condition on a visual analogue scale was noted in 93.3% of patients. As for the forced vital respiratory capacity, a positive response was 80.0% (improvement in one out of four patient); on the ray pattern, the improvement was 934% (improvement in 66.7% of patients). Good LF tolerability was recorded in 6 patients, 7 patients reported adverse reactions which did not result in treatment discontinuation; and 2 patients discontinued the therapy in 3 months due to sacred fire which was successfully treated with antibiotics (n = 1), nausea, vomiting, and diarrhoea (n = 1). Conclusion. According to the results, LF can be used as a second or third line of therapy in chronic and/or refractory sarcoidosis. Keywords: sarcoidosis, therapy, leflunomide.
Selective Immunoglobulin A Deficiency that Developed in the Long-Term Period after Rituximab Therapy
Authors:   Moscow Regional Research Clinical Institute named after M.F. Vladimirskiy, Moskalets O.V. ,   Moscow Russian Federation
Published: October 2022

Objective of the Paper: To demonstrate the possibility of developing late-onset hypoimmunoglobulinemia after a course of immunosuppressive therapy. Key points. A clinical observation is presented when a selective immunoglobulin A deficiency gradually developed in a patient with Sjögren's disease and MALT-lymphoma, who received rituximab for several years. It was associated with increased frequency of acute respiratory infections. The molecular mechanisms of secondary antibody deficiencies followed by immunisupressive therapy are virtually unknown and are likely to be heterogenous. It is necessary to carry out a differential diagnosis with primary immunodeficiencies. Conclusion. This clinical observation confirms that when choosing rituximab or other anti-B-cell drugs as basic therapy, one should be aware of the possible development of hypoimmunoglobulinemia both during treatment and in the long-term period. Before starting treatment with rituximab, one must determine the initial levels of serum immunoglobulins to assess the risk of infectious complications and identify primary immunodeficiencies and monitor them even after discontinuation of the drug, particularly in patients with infections. Keywords: rituximab, antibody deficiency, immunoglobulin A, Sjogren’s syndrome, lymphoma.
‘We Are the Citizens of a Nation Called Lebanon’
Authors: Haidar Riwa
Published: October 2022

This article looks at how the confessional system of government in Lebanon creates limits in younger citizens’ professional opportunities. These limitations are not directly implemented by the government system, per se, as this article will show. Instead, it is through it that the sectarian identification amongst the older generations became what it is today, and how, in the case of Lebanon specifically, it indirectly led to the following of strict quotas that, instead of offering equal opportunities, created sectarian obstacles that could not be overcome. This article focuses on the youth of Lebanon, notably university students, portraying how in parallel to the limitations faced and frustrations expressed by the students, a new nationalistic identification is rising amongst them as they come to realisation with the issues of confessionalism as a political system.
The History in Procession
Authors: Shekarchi Ahmad
Published: October 2022

This article investigates emerging patterns of pilgrimage in the context of Shiʿite Islam and studies the case of Arbaʿyin based on two weeks of participatory observation, walking from the al-Faw peninsula in the far south of Iraq to the city of Karbalâ. I identify three narratives in this pilgrimage—tribal, ideological and orthodox—and discuss their commonalities and differentials. The maʿāzīb system of the tribal narrative is the core of the comparison, yet each narrative is interrelated with the others through the central themes of war, political Islam and religious seminaries. In the last section, I explore recent transformations of these themes as well as the pilgrims’ configuration. The tribal narrative of Arbaʿyin presents itself as a rival to the ideological narrative pilgrimage. Although this narrative is based on the social structure of a tribal system, it struggles with new transformations and challenges in form and content.
Folktales, Folksongs, and Proverbs in Lur/Iranian Daily Life
Authors: Hegland Mary Elaine
Published: October 2022

Erika Friedl, Folk Tales from a Persian Tribe: Forty-Five Tales from Sisakht in Luri and English, Collected, Transcribed, Translated and Commented on by Erika Friedl (Dortmund, Germany:Verlag für Orientkunde, 2007); Folktales and Storytellers of Iran: Culture, Ethos, and Identity (London: I.B. Tauris, 2014); Warm Hearts and Sharp Tongues: Life in 555 Proverbs from the Zagros Mountains of Iran (Vienna: New Academic Press, 2015); and Folksongs from the Mountains of Iran: Culture, Poetics and Everyday Philosophies (London: I.B. Tauris, 2018).
Charging Drivers by the Gallon vs. the Mile: An Equity Analysis by Geography and Income in California
Authors:   University of California, Los Angeles, Speroni Samuel , Speroni Asha Weinstein ,   San Jose State University, Manville Michael ,   University of California, Los Angeles, Taylor Brian D. ,   University of California, Los Angeles
Published: October 2022

This study used data from the 2017 National Household Travel Survey California Add-On sample to explore how replacing the current state vehicle fuel tax with a flat-per-mile-rate road-user charge (RUC) would affect costs for different kinds of households. We first estimated how household vehicle fuel efficiency, mileage, and fuel tax expenditures vary by geography (rural vs. urban) and by income. These findings were then used to estimate how much different types of households pay in the current per-gallon state fuel tax, what they would pay if the state were to replace fuel taxes with a flat-rate road-usage charge (RUC) that would generate revenues similar to the current state fuel tax (2.52¢ per mile driven), and the difference in household expenditures between the fuel tax and RUC. We find that rural households tend to drive more miles and own less fuel-efficient vehicles than urban ones, so they pay comparatively more in fuel tax and would pay more with the RUC as well. However, this rural/urban variation is less for the RUC than the fuel tax, so moving to a flat-rate RUC would redistribute some of the overall tax burden from rural households (that drive more miles in fuel-thirsty vehicles) to urban households (that drive fewer miles in more fuel-efficient vehicles). Transitioning from the fuel tax to RUC would also generally shift the fuel tax burden from lower-income to higher-income households, with one exception: expenditures would rise for low-income urban households. However, the variation in the tax incidence between the gas tax and RUC is quite modest, amounting to less than one dollar per week for both urban and rural households at all income levels.
APPLICATION OF DEEP BOLTZMANN MACHINE IN DIAGNOSIS PROCESSES OF HEPATITIS TYPES B & C
Authors:   Islamic Azad University, Oftadeh Hadis , Manthouri Mohammad ,   Shahed University
Published: October 2022

Correct diagnosis of diseases is the main problem in medicine. Artificial intelligence and learning methods have been developed to solve problems in many fields, such as biology and medical sciences. Correct diagnosis before treatment is the most challenging and the first step in achieving proper cures. The primary objective of this paper is to introduce an intelligent system that develops beyond the deep neural network. It can diagnose and distinguish between Hepatitis types B and C by using a set of general tests for liver health. The deep network used in this research is the Deep Boltzmann Machine (DBM). Learning components within Restricted Boltzmann Machine (RBM) lead to intended results. The RBMs extract features to be used in an efficient classification process. An RBM is robust computing and well-suited to extract high-level features and diagnose hepatitis B and C. The method was tested on general items in laboratory tests that check the liver’s health. The DBM could predict hepatitis type B and C with an accuracy between 90.1% and 92.04%. Predictive accuracy was obtained with10-fold cross-validation. Compared with other methods, simulation results on DBM architecture reveal the proposed method’s efficiency in diagnosing Hepatitis B and C. What made this approach successful was a deep learning network in addition to discovering communication and extracting knowledge from the data.
Touchscreen Cognitive Tools for Mild Cognitive Impairment and Dementia Used in Primary Care Across Diverse Cultural and Literacy Populations: A Systematic Review
Authors: Giaquinto Francesco , Battista Petronilla , Angelelli Paola
Published: October 2022

Background: Touchscreen cognitive tools opened new promising opportunities for the early detection of cognitive impairment; however, most research studies are conducted in English-speaking populations and high-income countries, with a gap in knowledge about their use in populations with cultural, linguistic, and educational diversity. Objective: To review the touchscreen tools used in primary care settings for the cognitive assessment of mild cognitive impairment (MCI) and dementia, with a focus on populations of different cultures, languages, and literacy. Methods: This systematic review was conducted following the PRISMA guidelines. Studies were identified by searching across MEDLINE, EMBASE, EBSCO, OVID, SCOPUS, SCIELO, LILACS, and by cross-referencing. All studies that provide a first-level cognitive assessment for MCI and dementia with any touchscreen tools suitable to be used in the context of primary care were included. Results: Forty-two studies reporting on 30 tools and batteries were identified. Substantial differences among the tools emerged, in terms of theoretical framework, clinical validity, and features related to the application in clinical practice. A small proportion of the tools are available in multiple languages. Only 7 out of the 30 tools have a multiple languages validation. Only two tools are validated in low-educated samples, e.g., IDEA and mSTS-MCI. Conclusion: General practitioners can benefit from touchscreen cognitive tools. However, easy requirements of the device, low dependence on the examiner, fast administration, and adaptation to different cultures and languages are some of the main features that we need to take into consideration when implementing touchscreen cognitive tools in the culture and language of underrepresented populations.
Diarios de pandemia. Autoetnografía pedagógica de un docente universitario en Chile
Authors: González González Jaime
Published: October 2022

En el caso del sistema universitario en Chile, este tomó la decisión de suspender las actividades académicas presenciales en la segunda quincena de marzo de 2020. Independiente de los planes y directrices gubernamentales, la Universidad de Chile primero y los distintos planteles académicos después, modificaron su mecánica de trabajo desde el tradicional formato presencial, a una modalidad telemática para generar reuniones académicas y sobre todo impartir docencia de pre y postgrado. De esta manera, la academia chilena se integró a la tendencia mundial de trabajar desde una modalidad online, integrando a estudiantes y docentes al teletrabajo. El nuevo modo de proceder tuvo implicancias en los saberes de educandos y profesores, sobre todo en el terreno del manejo tecnológico de los nuevos soportes de comunicación digital. No obstante, el principal impacto que tuvo esta nueva mecánica en el profesorado fue en el campo metodológico, fuese en el terreno de la didáctica, fuese en el plano de la evaluación. Enseñar un contenido de manera telemática resultaba una práctica muy diferente a dictar cátedra de manera presencial. Así, las prácticas metódicas del profesorado sufrieron una serie de cambios mediados por el principio de ensayo y error. En este terreno, tanto estudiantes como docentes ejercieron el papel de educandos en un desafío pedagógico inédito en la historia de la academia tradicional.
PENGARUH KEPERCAYAAN, KEMUDAHAN DAN PERSEPSI RISIKO MENGGUNAKAN E-COMMERCE TERHADAP KEPUTUSAN PEMBELIAN ONLINE DI TOKOPEDIA.COM
Authors: Wahyuningtyas Yunita Fitri , Weasaga Marlina Sari
Published: October 2022

Penelitian ini bertujuan untuk mengetahui pengaruh kepercayaan, kemudahan dan persepsi risiko secara parsial maupun simultan terhadap keputusan pembelian secara online di tokopedia.com. Penelitian ini menggunakan pendekatan kuantitatif dengan mengumpulkan data melalui metode survei. Populasi dalam penelitian ini adalah pengguna tokopedia.com di Wilayah Umbulharjo Kota Yogyakarta. Teknik pengambilan sampel menggunakan metode purposive sampling, yaitu berdasarkan kriteria pengguna tokopedia.com di Wilayah Umbulharjo Kota Yogyakarta yang pernah membeli secara online di tokopedia.com. Sampel berjumlah 100 responden dengan teknik pengumpulan data menggunakan kuesioner. Uji validitas instrumen menggunakan confirmatory factor analysis, sedangkan uji reabilitas menggunakan alpha Cronbach. Teknik analisis yang digunakan adalah analisis regresi linier berganda. Hasil penelitian ini menunjukkan bahwa : (1) Kepercayaan berpengaruh positif terhadap keputusan pembelian, dibuktikan dari nilai t hitung sebesar 2,784 dengan nilai signifikansi sebesar 0.006 < 0.05 dan koefisien regresi memiliki nilai positif sebesar 0.189; (2) Kemudahan berpengaruh positif terhadap keputusan pembelian, dibuktikan dari nilai t hitung sebesar 5.406 dengan nilai signifikansi sebesar 0.000 < 0.05 dan koefisien regresi memiliki nilai positif sebesar 0.346; (3) persepsi risiko berpengaruh positif terhadap keputusan pembelian, dibuktikan dari nilai t hitung sebesar 4,848 dengan nilai signifikansi sebesar 0.000 < 0.05 dan koefisien regresi memiliki nilai positif sebesar 0.287; (4) Kepercayaan, Kemudahan dan Persepsi Risiko secara simultan berpengaruh positif terhadap keputusan pembelian, dibuktikan dengan hasil F hitung sebesar 74,526 > 2,70 dengan signifikansi sebesar 0.000 ; (5) Besarnya pengaruh Kepercayaan, Kemudahan, dan Persepsi Risiko terhadap keputusan pembelian (Adjusted R Square) adalah sebesar 69 %. Persamaan regresi yang diperoleh adalah Y= 4,548 + 0,189X₁ + 0,346X₂ + 0,287X₃ + e.
EVALUASI IMPLEMENTASI STRATEGI PEMASARAN CAFÉ KOPI LUWAK MATARAM KOTA YOGYAKARTA
Authors: Chasanah Uswatun , Grenia Feza
Published: October 2022

Penelitian ini bertujuan untuk mengetahui strategi pemasaran yang diterapkan di Café Kopi Luwak Mataram. Metode yang digunakan dalam penelitian ini yaitu metode kualitatif yang bersifat deskriptif. Adapun sumber data yang digunakan adalah data primer dan data sekunder yang kemudian data akan dianalisis mulai dari pengumpulan data, reduksi data, penyajian data hingga penarikan kesimpulan.

Berdasarkan analisis data yang dilakukan, diperoleh kesimpulan bahwa Café Kopi Luwak Mataram sudah mengetahui dan menerapkan strategi pemasaran dalam usahanya meskipun belum optimal serta marketing mix yang dilakukan terdiri dari 4P (price,product,place,promotion) serta kualitas pelayanan. Untuk produk yang dijual cukup bervariasi, untuk harga yang diterapkan Café Kopi Luwak Mataram sudah cukup bersaing, sedangkan untuk tempat kurang strategis, dan untuk promosi yang diterapkan Café Kopi Luwak Mataram kurang gencar, tetapi dari segi kualitas pelayanan Café Kopi Luwak Mataram sangat baik, sehingga membuat konsumen betah dan nyaman untuk berada di Café Kopi Luwak Mataram. Untuk solusi yang diterapkan Café Kopi Luwak Mataram harus meningkatkan kembali promosi penjualan agar lebih baik untuk kedepannya.
PERAN PENGETAHUAN AKUNTANSI DAN KEPRIBADIAN WIRAUSAHA DALAM PENGAMBILAN KEPUTUSAN INVESTASI
Authors: Ayulansae Nurani Putri , Priyastiwi Priyastiwi
Published: October 2022

Informasi akuntansi merupakan informasi yang diperlukan oleh seorang wirausaha untuk membuat keputusan investasi. Kepribadian wirausaha yang baik akan membuat seseorang ingin terus mengembangkan usaha yang telah dimilikinya, salah satu cara untuk mengembangkan usaha yang telah ada adalah dengan melakukan investasi. Pencatatan transaksi keuangan sangat penting demi keuntungan yang ingin diraih untuk kelangsungan usaha agar usaha tidak berhenti ditengah jalan. Namun saat ini banyak wirausaha yang tidak memiliki pengetahuan akuntansi yang baik sehingga banyak wirausaha yang tidak melakukan pencatatan atas transaksi-transaksi pada usaha mereka sehingga tidak ada informasi keuangan yang dihasilkan untuk membuat keputusan investasi. Penelitian ini bertujuan untuk mengetahui adanya hubungan yang positif dan signifikan antara pengetahuan akuntansi dan kepribadian wirausaha terhadap penggunaan informasi akuntansi dalam pembuatan keputusan investasi. Teknik analisis data yang digunakan adalah teknik analisis regresi linear berganda. Hasil penelitian ini menunjukkan bahwa pengetahuan akuntansi dan kepribadian wirausaha berpengaruh positif dan signifikan terhadap penggunaan informasi akuntansi dalam pembuatan keputusan investasi.
UPAYA PENINGKATAN KINERJA KARYAWAN PADA VENDOR SABLON CROWNIC APPAREL YOGYAKARTA
Authors: Subkhan Muhammad , Nur Farda Adlhan
Published: October 2022

Penelitian ini bertujuan untuk mengetahui upaya peningkatan kinerja karyawan ditujukan kepada Owner Vendor Sablon Crownic Apparel, menyusun strategi peningkatan kinerja karyawan, dan mendeskripsikan faktor internal dan eksternal yang mendorong kinerja karyawan vendor sablon crownic apparel. Dalam penelitian ini menggunakan metode deskriptif kualitatif dengan analisis tentang analisis upaya peningkatan kinerja karyawan pada Crownic Apparel. Teknik pengumpulan data menggunakan teknik wawancara, pengamatan (observasi), dan studi dokumen. Adapun langkah-langkah dalam teknik analisis data dalam penelitian ini adalah reduksi data, penyajian data, dan penyimpulan atau verifikasi. Hasil dari penelitian ini menunjukkan bahwa perusahaan Crownic Apparel telah melakukan upaya peningkatan kinerja karyawan. Dengan pemberian pelatihan-pelatihan secara eksternal serta dengan mentoring yang selalu dilakukan oleh manajer di setiap inovasi maupun teknik-teknik baru dalam pekerjaan. Karyawan yang berprestasi akan diberikan sebuah penghargaan oleh perusahaan.
STRATEGI PENGEMBANGAN BENDUNG TEGAL SEBAGAI OBJEK DAN DAYA TARIK WISATA ALAM DI DESA WISATA KEBONAGUNG KAPANEWON IMOGIRI KABUPATEN BANTUL
Authors: Martanto Eko , Tipau Ariel Ardi
Published: October 2022

Objek Wisata Bendung Tegal di Kapanewon Imogiri, Kabupaten Bantul, Yogyakarta merupakan salah satu bendungan yang dibangun untuk membendung aliran Sungai Opak untuk mengairi area persawahan yang ada disekitarnya. Selain berfungsi sebagai pengairan, bendungan ini juga dikembangkan sebagai kawasan wisata oleh pemerintah daerah sekitar. Pengembangan Wisata Bendung Tegal mutlak dilakukan karena hal ini dapat mendorong meningkatnya kondisi perekonomian dari warga yang ada disekitarnya. Partisipasi masyarakat yang dilakukan dalam pengembangan objek wisata Bendung Tegal dengan cara membuat iuran setiap bulannya bagi masyarakat yang ada di Desa Wisata Kebonagung itu sendiri dalam bentuk pemberian dana yang diberikan secara sukarela. Dimana dana tersebut diperoleh dari masyarakat setempat maupun pemuda Karang Taruna yang ikut berpartisipasi dalam pengelolaan maupun pengembangan objek wisata Bendung Tegal. Selain itu juga perlu dilakukan pembenahan baik sarana dan prasarana untuk meningkatkan tingkat kunjungan wisatawan ke Bendung Tegal dan selain itu perlunya media promosi yang efektif agar Obyek Wisata Bendung Tegal semakin dikenal oleh masyarakat secara umum.
Penerapan Teori Bilangan Dominasi Jarak Dua Pada Pemilihan Lokasi Pangkal Ojek Online
Authors: Umilasari Reni , Saifudin Ilham , Ayyasy Afkar
Published: October 2022

Misalkan G adalah graf terhubung dan S_2 merupakan himpunan dominasi jarak dua dari graf G. S_2 didefinisikan sebagai subset dari V(G) yang sedemikian hingga titik-titik pada G yang tidak terhubung dengan S_2 memiliki jarak maksimal 2 terhadap S_2. Kardinalitas minimum dari S_2 dinotasikan dengan Gamma_2(G) dan disebut bilangan dominasi. Pada artikel ini, ditentukan bilangan dominasi jarak dua dari hasil operasi shackle titik dan sisi pada graf Bipartit lengkap dan graf Tripartit lengkap, yaitu Shack (K_(m,n),v,k) m>=2, n>=3, Shack(K_(m,n),e,k) m>=2, n>=3, Shack(K_(m,n,r),v,k) m,n,r>=2, dan Shack(K_(m,n,r),e,k) m,n,r>=2. Implementasi konsep ini digunakan untuk menentukan jumlah minimum pos pangkalan ojek di Kabupaten Jember. Sumbersari, Patrang dan Kaliwates masing-masing direpresentasikan ke dalam graf yaitu (Sb-Graf), (Pt-Graf), dan (Kl-Graf) dengan ketentuan warung atau kedai, persimpangan jalan, dan masjid direpresentasikan sebagai titik dan jarak antar lokasi tersebut digambarkan sebagai sisi. Hasil akhir dari penelitian ini diperoleh jumlah minimum pos pangkalan ojek, yaitu 8 pos (Sumbersari), 7 (Patrang), dan 5 (Kaliwates) dari 169 titik yang tersebar di ketiga Kecamatan tersebut. Dari jumlah tersebut diimplementasikan menggunakan aplikasi ARCGIS yang berbasis SIG (Sistem Informasi Geografis) pada ketiga kecamatan tersebut.
Multivariate Adaptive Generalized Poisson Regression Splines untuk Pengembangan Model Prediksi Produksi Padi di Kabupaten Bojonegoro
Authors: Kartini Alif Yuanita , Ishlahuddin Muhammad
Published: October 2022

Produksi padi di kabupaten Bojonegoro terus mengalami penurunan yang disebabkan oleh banjir dan serangan hama. Sehingga diperlukan suatu penelitian untuk mendapatkan variabel yang berpengaruh signifikan terhadap produksi padi di kabupaten Bojonegoro serta prediksi produksi padi untuk beberapa waktu mendatang menggunakan metode Multivariate Adaptive Generalized Poisson Regression Splines (MAGPRS). Dalam penelitian ini menggunakan metode MAGPRS karena tidak jelasnya bentuk hubungan antara variabel respon terhadap variabel prediktor, serta variabel respon yang digunakan merupakan variabel jumlah yang diduga berdistribusi poisson. Data yang digunakan berupa data di setiap kecamatan di kabupaten Bojonegoro pada tahun 2021 yaitu jumlah produksi padi (Y), luas lahan (X1), jumlah kelompok tani (X2), jumlah penggunaan pupuk NPK (X3), jumlah penggunaan pupuk petroganik (X4), jumlah penggunaan pupuk P-36 (X5), jumlah penggunaan pupuk urea (X6), jumlah penggunaan pupuk ZA (X7), dan serangan OPT (X8). Hasil analisis menunjukkan bahwa model MAGPRS terbaik adalah model dengan nilai BF sebesar 16, MI sebesar 3 dan MO sebesar 2 dengan GCV bernilai 0,33677 dan R2 bernilai 0,980. Variabel luas lahan memberikan kontribusi sebesar 100 %, diikuti dengan variabel jumlah penggunaan pupuk petroganik, jumlah penggunaan pupuk NPK, jumlah kelompok tani, jumlah penggunaan pupuk urea, jumlah serangan OPT dan jumlah penggunaan pupuk ZA. Model MAGPRS mempunyai tingkat akurasi sebesar 92,10 % untuk prediksi jumlah produksi padi di kabupaten Bojonegoro.
Implementasi Model Indeks Tunggal dalam Pembentukan Portofolio Optimal pada Saham Syariah MES BUMN 17 Periode New Normal
Authors: Abdullah Syarif , Huda Miftahul , Chasanah Sri Istiyarti Uswatun , Mursyidah Himmatul , Ikhsan Fajri , Susilo Sidik , Firmansyah Alfian , Fauzi Rizqi , Boy Kevin Dion Valen
Published: October 2022

Pasar modal merupakan salah satu wadah dalam berinvestasi saham. Pilihan indeks saham dalam pasar modal di Indonesia dapat dilihat pada Bursa Efek Indonesia (BEI), dimana beberapa diantaranya memiliki prinsip syariah. Salah satu indeks saham yang memiliki prinsip tersebut adalah MES BUMN 17. Pada masa new normal tidak bisa dipungkiri bahwa dalam berinvestasi akan ada kemungkinan dalam mendapatkan imbal hasil dan risiko yang tidak terduga. Tujuan dalam penelitian ini adalah membentuk portofolio yang optimal pada 17 saham yang tergabung dalam MES BUMN 17 pada masa new normal. Penelitian ini menggunakan Single Index Model. Data yang digunakan pada penelitian ini yaitu pada periode new normal, yakni pada periode Desember 2020 s.d November 2021. Hasil penelitiaan didapatkan bahwa pada periode new normal, pada saham MES BUMN 17, memberikan keuntungan yang optimal. Dari 17 saham yang terdapat pada MES BUMN 17, didapatkan 3 saham yaitu saham BRIS (Bank Syariah Indonesia Tbk.) dengan proporsi portofolio 67.093%, saham PTBA (Bukit Asam Tbk.) dengan proporsi portofolio 21.481% dan saham IPCC (Indonesia Kendaraan Terminal Tbk.) dengan proporsi portofolio 11.426%. Expected return portofolio optimal dan risiko portofolio optimal masing-masing sebesar 0.82% dan 0.35% per minggu. Artinya dalam skenario portofolio optimal yang diperoleh dalam analisis ini masih memberikan keuntungan bagi para investor pada periode new normal.
La problemática del agua en el contexto de las ciencias sociales y las ciencias ambientales
Authors:   Universidad de Guanajuato, Valdes Cobos Alberto
Published: October 2022

A medida que nos adentramos en el siglo xxi, gobiernos, empresas, académicos y organizaciones de la sociedad civil coinciden en que padecemos una crisis del agua a escala planetaria. Los prolongados periodos de sequía y el imperativo privatizador de la globalización neoliberal evidencian cada vez más la crisis sociodemográfica, política y ambiental del agua, configurando riesgos y escenarios de futuro con potenciales conflictos sociopolíticos y de guerras por el agua. Ante esta crisis global, la Organización de las Naciones Unidas (2015), a través de la Agenda 2030 de Desarrollo Sostenible, ha reivindicado el objetivo de “garantizar la disponibilidad de agua y su gestión sostenible y el saneamiento para todos”. Esta es una crisis también presente en América Latina, que hunde sus raíces en la conquista europea y se basa en una concepción de la naturaleza y del agua como bienes económicos ilimitados, con lo cual se pone en entredicho la sostenibilidad ambiental del sistema capitalista. Cabe señalar que México tampoco escapa a dicha problemática, especialmente las regiones del centro y norte que ya empiezan a enfrentar los estragos del estrés hídrico. En ese sentido, las universidades y centros de investigación tienen mucho que hacer para abordar la complejidad y crisis del agua a través de estrategias epistémicas como la disciplina, la interdisciplina y la multidisciplina. Este artículo tiene por objetivo reali- zar una aproximación sociológica a la problemática del agua a nivel global y nacional a partir del trabajo conjunto entre ciencias sociales y ciencias ambientales, así como de la sociología ambiental. Es conveniente destacar que este trabajo se confeccionó con base en una revisión documental especializada sobre la temática en cuestión.
Consejos maternos que hablan memoria: conversaciones con mujeres de la comunidad mapuche Lago Rosario
Authors: Verónica Bleger Mariel
Published: October 2022

Este trabajo surge como reflejo de mis primeras aproximaciones respecto a relatos por parte de mujeres que se fueron sucediendo en mi trabajo de campo en la comunidad mapuche Lago Rosario, ubicada a kilómetros de Esquel en la provincia de Chubut, Patagonia Argentina. Lo que caracteriza a las mismas es la importancia del recordar ciertos consejos maternos que devienen en hilo conductor de las infancias, las maternidades y las divisiones sociales del trabajo en las biografías de este grupo de mujeres. Estos consejos orientan formas de estar en el mundo y develan nuevas tramas de significados y nociones de resistencia, rebeldía y solidaridad en entramados socioculturalmente significativos.
An 8-bit digital-to-time converter with pre-skewing and time interpolation
Authors: Lee Daniel Junehee , Yuan Fei , Khan Gul , Zhou Yushi
Published: October 2022

This study presents an 8‐bit delay line digital‐to‐time converter (DTC) with pre‐skewing and digital time interpolation. Pre‐skewing that lowers the per‐stage‐delay of delay lines beyond that set by the chosen technology is investigated. A cascode tri‐state inverter is proposed to improve the isolation between the input and output of interpolation cells so as to improve the linearity of the time interpolator. Design considerations that critically affect the linearity of the DTC are examined in detail. The impact of the slope of the inputs of the time interpolator on the latency and linearity of the interpolator is analysed and the maximum slope of the input of interpolators yielding the minimum latency without sacrificing linearity, is obtained. The timing errors of DTC are investigated and the considerations of the layout of the DTC are examined. The DTC is designed in a TSMC 65 nm 1.0 V CMOS technology and analysed using Spectre with BSIM3V3 device models. Post‐layout simulation results show the DTC offers 3.6 ps resolution, 580 MS/s conversion rate, and consumes 383 μW.
PERILAKU TEKANAN AIR PORI PADA BENDUNGAN BAJULMATI MULAI PENGISIAN HINGGA TAHUN 2020
Authors: Ardiansyah Rahman Hakim , Khurtumi Nofyar Dwi
Published: October 2022

Bendungan Bajulmati mulai pengisian awal waduk pada tahun 2015 dan pemantauan tekanan air pori dilakukan dengan pengukuran pisometer pneumatik yang dipasang di dalam tubuh dan pondasi bendungan. Pemantauan rutin dan interpretasi yang baik dari data pembacaan pisometer yang terpasang pada bendungan perlu dilakukan guna mengetahui perilaku tekanan air pori pada bendungan, sehingga dapat mengetahui secara dini masalah yang mungkin sedang terjadi, mengingat bahwa tekanan air pori dapat mempengaruhi keamanan stabilitas lereng. Tujuan dari penelitian ini adalah untuk mendapatkan perilaku tekanan air pori pada Bendungan Bajulmati mulai dari pengisian awal waduk hingga tahun 2020. Perilaku tekanan air pori pada Bendungan Bajulmati, dilakukan dengan pemodelan SEEP/W kondisi transient, kemudian dibandingkan dengan data hasil pengukuran pisometer di lapangan. Hasil pemodelan menunjukkan bahwa muka air waduk mempengaruhi perilaku tekanan air pori pada tubuh bendungan. Nilai tekanan air pori hasil pemodelan nilainya lebih rendah daripada pengukuran pisometer di lapangan dengan deviasi sebesar 2,2 dan 2,1 mH2O, namun demikian data pembacaan pisometer PP6 dan PP7 masih menunjukkan trend yang sama dengan hasil pemodelan, sehingga disimpulkan bahwa kondisinya masih wajar.
The role of savings of households in development of the national economy
Authors: Shaposhnykov K. , Krylov D. , Lozychenko O.
Published: October 2022

Households are one of the key economic actors that play an important role in the national economy development. One of the most important components of the influence of these entities on the development of economic relations is the ability to form within the national economy financial resources for the national economy development, which occurs through the mechanism of the transformation of household savings into investment resources. Thus, the issues of studying the formation of households’ savings, their effective involvement in the financial system, maintaining real value, and finding new tools to stimulate the motivation of these economic entities to make savings remain relevant among scientists. Within the article, theoretical aspects of the impact of households’ savings on the national economy development is deepened. The analysis of their essence allowed to describe the model of their formation in the national economy system, specify the types of such savings (organized, unorganized) and substantiate the peculiarities of the formation and the role in the development of the country. A detailed analysis of the impact of households’ savings on the different sectors and sectors of economy allowed us to identify two types of such impact, namely: direct impact – households directly invest their savings in investment projects; indirect impact – households transfer their accumulated funds to financial intermediaries. The obtained results provided an opportunity to deepen the understanding of the existence of different ways of influencing household savings on the national economy development, and state the complexity of this influence, its static nature. Moreover, as a result of the research, a complex interaction between households’ savings and the national economy is identified. However, more attention was focused on understanding the impact of households’ savings on economic development. Two types of influence were identified, namely: positive and negative. This allowed us to conclude that it is important to actively involve public authorities in regulating the formation and use of households’ savings, not only in terms of stimulating their accumulation and use, but also in minimizing the risks of the destructive impact of such resources on stable functioning of the national economy.
Intangible motivation of the staff of modern enterprises
Authors: Leskova S.
Published: October 2022

The motivation of the staff of modern enterprises has changed, and the method of “whip and gingerbread” demotivates employees rather than motivates them. Modern enterprises should use more methods of intangible motivation, which affects the loyalty and involvement of employees, creates in them the sense of security and care on the part of enterprise management. Improving the efficiency of personnel management depends on systematic approach to the application of intangible motivation of employees, the formation of motivational programs for middle management. For this purpose the practitioners advise to pay more attention to the motivation of enterprise managers and use such methods as remote work, extra time off, rapid career growth, tuition fees, opportunities for self-realization. Remote work makes it possible to preserve health and life of employees, encourages them to self-organization, self-control and self-motivation, additional vacations or holidays give employees the opportunity to relax and gain strength, which motivates them to create new ideas. Opportunity for self-realization, pay for training and rapid career growth motivates employees with high potential who can become leaders in the future, continuously learn and improve their competence. The investigation highlights the most common methods of intangible motivation of personnel used in modern enterprises, in particular: public recognition of merit, career planning, delegation of managerial powers, increasing personal responsibility, autonomy in solving tasks, employer brand, improving comfort in the workplace, organization of competitions for the title of the best employee, etc. The recommendations of scientists on the organization of intangible motivation, motivational measures of moral, psychological, organizational and social motivation are given. Measures of moral motivation include praise and recognition; psychological motivation – building the system of values and individual approach to each employee, organizational motivation – improving working conditions, organizing ergonomic space, providing flexible work schedule; social motivation – training of employees, participation in the decision-making process. Analysis of the motivational model of the XXI century, based on the innate human psychological needs of autonomy, purpose and skill, the satisfaction of which results in greater achievements of employees. It is shown that the methods of intangible motivation have positive effect on achieving better results in employees, team building and development, reduce staff turnover, improve product quality (goods, works, services) and increase the competitiveness of the enterprise.
农田水利工程施工技术的难点及质量控制
Authors: 曹 太军
Published: October 2022

在国民经济的发展过程中，逐渐突出了农业产业的重要地位，与社会经济水平的提升具有紧密联系。在农田水利工程项目的建设过程中，受到了国家政策和社会各界的大力支持，为此类工程建设作业的推广和发展奠定了良好的基础，并且能够促进农业经济水平的提升。在开展农田水利工程施工作业的过程中，容易出现施工技术等方面的难题，阻碍了施工作业的顺利开展。现阶段需要针对此类难题予以全面分析，采取有针对性的问题解决措施，加大对技术应用质量的控制力度，有效提高农田水利工程施工技术的应用水平。
Sosialisasi Penanganan Stunting Sebagai Upaya Sustainable Development Goals Desa Keban Agung
Authors: Jody Afif Setiawan  , Ramona Preselia  , Lulu Artafia  , Rahmad Iman  , Reigah W Andrean  , Hezron Swandi  , Julfitri Siregar  , Distri Imelia  , Cindi Konera  , Barika Barika
Published: October 2022

Prevention of stunting in children in Indonesia still needs attention, including Bengkulu. One form of stunting prevention activity is through community service activities. This service activity is in the form of socialization about stunting prevention in Keban Agung Village, Seluma Regency. The purpose of implementing stunting socialization is to provide self-awareness to villagers about the importance and dangers of stunting. The method used is observation and socialization about stunting. The results obtained are that the residents of Keban Agung Village receive early knowledge and awareness to prevent stunting in children and are aware of implementing a healthy lifestyle to avoid stunting and other diseases.
Comparison of Surgical Outcomes of Two-muscle Surgery in Children with Large-angle Intermittent Exotropia
Authors: Choi Yoon Seok , Chun Bo Young
Published: October 2022

Purpose: To evaluate the long-term results of 2-muscle surgery in children with large-angle intermittent exotropia (IXT), comparing bilateral lateral rectus recession (BLR) with unilateral lateral rectus recession & medial rectus resection (RR).Methods: Ninety-two children with IXT of 40 prism diopter or more, who underwent BLR or RR were included in this retrospective study. Final successful alignment rates, and cumulative probabilities of surgical success at 3 years postoperatively were analyzed and compared using Kaplan-Meier survival analysis between the two groups.Results: At 3 years after surgery, 37 (67.3%) of 55 patients in the BLR group achieved successful alignment; 18 (32.7%) had undercorrection, and none of them had overcorrection. In the RR group, 34 (92%) of 37 patients were successfully aligned, two (5%) had undercorrection, and one (3%) had an overcorrection at 3 years after surgery. There was a statistically significant difference in postoperative results between the two groups (p = 0.0012). The cumulative probabilities of surgical success at 3 years postoperatively analyzed using the Kaplan-Meier survival curve were 63% in the BLR group and 92% in the RR group. Postoperative mean recurrence time was 45 months in the BLR group and 50 months in the RR group, showing a significant difference between the two groups (p = 0.0006).Conclusions: The unilateral RR procedure demonstrated more favorable long-term postoperative outcomes than BLR procedure in patients with large-angle IXT.
Prognostic Factors for Visual Outcomes in Acute Anterior Optic Neuritis Using Optical Coherence Tomography
Authors: Park Hyun Young , Hong Samin , Kim Sangah
Published: October 2022

Purpose: To identify the clinical characteristics and predictors of visual outcomes in acute anterior optic neuritis patients treated with high-dose steroid pulse therapy using spectral domain optical coherence tomography (SD-OCT).Methods: In this study, the medical records of 34 acute anterior optic neuritis patients treated with intravenous high-dose steroid pulse therapy and followed-up for at least 3 months were retrospectively reviewed. The patients were divided into two groups based on the final best-corrected visual acuity (BCVA); group 1 (n = 23) had a final BCVA ≥20/32, while group 2 (n = 11) had a final BCVA <20/32. Clinical characteristics and optical parameters obtained using SD-OCT were evaluated to identify factors influencing the final visual outcome.Results: There were no statistically significant differences in clinical or demographic data between the two groups. Peripapillary retinal nerve fiber layer (pRNFL) swelling at initial presentation was less common (p = 0.015), and the time to pRNFL thickness stabilization was longer (p = 0.016), in group 1. Multivariate logistic regression demonstrated better final visual acuity for patients in whom pRNFL thickness stabilization took longer, as well as in those with a smaller reduction in macular ganglion cell-inner plexiform layer (mGCIPL) thickness, and those without recurrence (p = 0.002, 0.016, and 0.035, respectively).Conclusions: Intravenous high-dose steroid pulse therapy much improved long-term visual outcomes in acute anterior optic neuritis patients with delayed pRNFL thickness stabilization, a smaller mGCIPL thickness reduction, and no recurrence. This suggests that inner retinal layer thickness and recurrence after stabilization may serve as biomarkers for final visual acuity after intravenous steroid treatment in acute anterior optic neuritis.
Asthma Phenotypes and the Microbiome
Authors: Ndum Ogechukwu , Huang Yvonne J.
Published: October 2022

Asthma is characterised by episodic bronchospasm, airway hyperreactivity, and airway inflammation. Current treatment is aimed at reversing bronchospasm with bronchodilators and decreasing airway inflammation with corticosteroids. Asthma patients as a collective group, however, have variable responses to treatment, and our understanding and view of asthma as a single pathologic process has evolved substantially. We now recognise that asthma is a heterogeneous disease with many phenotypes, as reflected by differences in natural history, complexity, severity, and responses to treatment. The underlying aetiologies for many phenotypes are poorly understood and likely multifactorial. Recent evidence increasingly supports an important role for microbial exposures and our microbiota as factors mediating asthma pathogenesis. However, given the phenotypic heterogeneity of asthma, we further propose that microbiota may play an additional role in shaping asthma phenotype. Beginning with a brief overview of concepts of asthma phenotypes and endotypes, the intent of this article is to summarise current knowledge of the microbiome in asthma, highlighting recent studies that have examined relationships between microbiota and phenotypic features of asthma. We conclude with a discussion of future research directions, considering important issues and challenges in this area of investigation.
European Society of Cardiology Chronic Coronary Syndromes Guidelines Review
Authors: Stanbury Samantha
Published: October 2022

New guidelines for the diagnosis and management of chronic coronary syndromes (CCS)1were released during the 2019 European Society of Cardiology (ESC) Congress. The new guidelines were discussed in multiple sessions with different formats across the congress; this review summarises some of the discussion among experts at the congress around what the new guidelines mean for the way they manage their patients with respect to antithrombotic treatment.

A significant change in the new guidelines versus previous guidelines published in 20132is an update in nomenclature from ‘stable’ coronary artery disease (CAD) to chronic coronary syndromes, to reflect the fact that patients with CCS are at continuous risk of heart attacks, strokes, and death. This highlights the need for effective preventive therapy to protect against these thrombotic events and maintain a state of relative stability in patients with CCS. To this end, a new recommendation in the 2019 guidelines is to consider intensification of antithrombotic therapy, using aspirin plus another antithrombotic agent, to provide enhanced long-term protection for patients with CCS at high risk of ischaemic events. This review places the new guideline recommendations in clinical perspective, including thorough presentations of case studies to illustrate how patients at greatest risk of ischaemic events can be identified, and treatment stratified accordingly. These case studies highlight the role of dual pathway inhibition (DPI) in managing CCS patients with the greatest need for cardiovascular protection, who are likely to derive the greatest benefit from this treatment strategy.