bluuebunny/crossref_metadata_2025 huggingface dataset:
Fluoxetine Mimics the Anorectic Action of Estrogen and Its Regulation of Circadian Feeding in Ovariectomized Female Rats
Authors: Nishimura Yuri , Mabuchi Kaori , Omura Natsumi , Igarashi Ayako , Miura Megumi , Mima Nanako , Negishi Hiroko , Morimoto Keiko , Takamata Akira
Published: March 2020

Our previous study demonstrated that chronic estrogen replacement in ovariectomized rats reduces food intake and augments c-Fos expression in the suprachiasmatic nucleus (SCN), specifically during the light phase. Here, we hypothesized that serotonergic neurons in the central nervous system (CNS), which have anorectic action and play a role in regulating circadian rhythm, mediate the light phase-specific anorectic action of estrogen, and that selective serotonin reuptake inhibitors (SSRIs) mimic the hypophagic action of estrogen. Female Wistar rats were ovariectomized and treated with estradiol (E2) or cholesterol by subcutaneously implanting a silicon capsule containing E2 or cholesterol. Then, half of the cholesterol-treated rats were injected with the SSRI fluoxetine (5 mg/kg) (FLX group), while the remaining rats in the cholesterol-treated group (CON group) and all those in the E2 group were injected with saline subcutaneously twice daily at the onsets of the light and dark phases. Both E2 and FLX reduced food intake during the light phase but not the dark phase, and reduced body weight gain. In addition, both E2 and FLX augmented the c-Fos expression in the SCN, specifically during the light phase. These data indicate that FLX exerts estrogen-like antiobesity and hypophagic actions by modifying circadian feeding patterns, and suggest that estrogen regulates circadian feeding rhythm via serotonergic neurons in the CNS.
From Attachment to a Sacred Figure to Loyalty to a Sacred Route: The Walking Pilgrimage of Arbaeen
Authors: Nikjoo Adel , Sharifi-Tehrani Mohammad , Karoubi Mehdi , Siyamiyan Abolfazl
Published: March 2020

Around 20 million Shia pilgrims shape one of the world’s biggest pilgrimages in Iraq, called “Arbaeen,” many of whom walk long distances to Karbala city as a part of the ritual every year. Faith in Imam Hussein, who was martyred in the battle of Karbala in 680 CE, is central among all pilgrims in this ritual, but the main question is how do the pilgrims’ faith and psychological cognitions translate into this spiritual journey with different meanings during the Arbaeen pilgrimage? The present study aims to discover the different social and psychological reasons for pilgrims’ feelings of attachment to Imam Hussein and to the Arbaeen pilgrimage route. Through 57 semi-structured in-depth interviews with pilgrims in two phases, Arbaeen 2014 and 2019, four different perceived roles for Imam Hussein including beloved, interceding, transformative, and unifier figure were found, leading pilgrims to feel an attachment to him. The current study mainly contributes to the literature by presenting an empirical analysis of Muslims’ experiences and perceptions of Islamic theology, and their loyalty to a sacred route through attachment to a sacred figure.
Identification of Immunogenic Epitopes That Permit the Detection of Antigen-Specific T Cell Responses in Multiple Serotypes of Group B Coxsackievirus Infections
Authors: Lasrado Ninaad , Gangaplara Arunakumar , Arumugam Rajkumar , Massilamany Chandirasegaran , Pokal Sayli , Zhou Yuzhen , Xiang Shi-Hua , Steffen David , Reddy Jay
Published: March 2020

Coxsackievirus group B (CVB) contains six serotypes that can affect various organs. Some of these organ-specific diseases such as myocarditis and pancreatitis can be caused by more than one serotype. Thus, development of immunological tools common to multiple serotypes is desired. This is especially critical for analyzing antigen-specific T cell responses at a single cell level. To this end, we made efforts to identify the immunogenic epitopes of CVB3 leading us to localize three T cell epitopes within the viral protein 1 (VP1) namely, VP1 681–700, VP1 721–740 and VP1 771–790. First, we confirmed their immunogenicity in the immunization settings. Second, we sought to verify the ability of VP1 epitopes to bind major histocompatibility complex (MHC) class II (IAk) molecules. Third, we created MHC class II (IAk) dextramers and tetramers and ascertained the T cell responses to be antigen-specific. Fourth, we analyzed the T cell responses in animals infected with CVB3 and noted the magnitude of antigen-specific T cell responses occurring in the order of VP1 721–740 and VP1 681–700 followed by VP1 771–790 as verified by proliferation assay and IAk tetramer staining. All epitopes induced interferon (IFN)-γ as a major cytokine. Finally, we investigated whether the VP1 tools generated for CVB3 can also be used to verify T cell responses in infections caused by other serotypes. To this end, we established the CVB4 infection model in A/J mice and found that the CVB4 infection led to the induction of IFN-γ-producing T cell responses primarily for VP1 721–740 and VP1 681–700. Thus, the VP1-specific tools, particularly IAk tetramers can be used to monitor anti-viral T cell responses in multiple CVB serotypes.
BoLA-DRB3 Polymorphism is Associated with Differential Susceptibility to Bovine Leukemia Virus-Induced Lymphoma and Proviral Load
Authors: Lo Chieh-Wen , Borjigin Liushiqi , Saito Susumu , Fukunaga Koya , Saitou Etsuko , Okazaki Katsunori , Mizutani Tetsuya , Wada Satoshi , Takeshima Shin-nosuke , Aida Yoko
Published: March 2020

Bovine leukemia virus (BLV) is the causative agent of enzootic bovine leucosis. However, less than 5% of BLV-infected cattle will develop lymphoma, suggesting that, in addition to viral infection, host genetic polymorphisms might play a role in disease susceptibility. Bovine leukocyte antigen (BoLA)-DRB3 is a highly polymorphic gene associated with BLV proviral load (PVL) susceptibility. Due to the fact that PVL is positively associated with disease progression, it is believed that controlling PVL can prevent lymphoma development. Thus, many studies have focused on the relationship between PVL and BoLA-DRB3. Despite this, there is little information regarding the relationship between lymphoma and BoLA-DRB3. Furthermore, whether or not PVL-associated BoLA-DRB3 is linked to lymphoma-associated BoLA-DRB3 has not been clarified. Here, we investigated whether or not lymphoma-associated BoLA-DRB3 is correlated with PVL-associated BoLA-DRB3. We demonstrate that two BoLA-DRB3 alleles were specifically associated with lymphoma resistance (*010:01 and *011:01), but no lymphoma-specific susceptibility alleles were found; furthermore, two other alleles, *002:01 and *012:01, were associated with PVL resistance and susceptibility, respectively. In contrast, lymphoma and PVL shared two resistance-associated (DRB3*014:01:01 and *009:02) BoLA-DRB3 alleles. Interestingly, we found that PVL associated alleles, but not lymphoma associated alleles, are related with the anti-BLV gp51 antibody production level in cows. Overall, our study is the first to demonstrate that the BoLA-DRB3 polymorphism confers differential susceptibility to BLV-induced lymphoma and PVL.
Pencegahan Terjadinya Tindak Pidana Nakotika pada Anak di Kelurahan Bantan Timur
Authors: Ramadhan M Citra , Marlina Marlina , Isnaini Isnaini
Published: March 2020

Perdagangan narkotika dewasa ini sangat mengkhwatirkan. Anak-anak yang notabene generasi penerus sebagai penentu kemajuan bangsa, terlibat dalam tindak pidana narkotika. Anak tidak hanya selaku penyalahguna, namun juga sebagai kurir dalam perdagangan narkotika. Hal ini tentu sangat memprihatikan, sehingga seluruh pemangku kepentingan (stake holder) harus berperan dalam melakukan pencegahan tindak pidana narkotika pada anak. Tindak Pidana narkotika mendapat ancaman pidana penjara dan denda yang berat. Inilah yang harus disadari oleh masayarakat, khususnya di daerah mitra, yaitu kelurahan Bantan Timur. Selain menyadarkan ancaman pidana, pendidikan hukum juga memberi tips agar anak tidak terlibat dalam tindak pidana narkotika, baik itu sebagai penyalahguna maupun kurir. Tentunya efektifitas dari tips pencegahan tersebut akan sangat ditetukan oleh lingkungan anak itu sendiri.
Tanggung Jawab Notaris atas Pemalsuan yang Dilakukan oleh Klien dalam Proses Pembuatan Akta
Authors: Rizkie Ayu , Arifin Muhammad , Ramlan Ramlan
Published: March 2020

Notary is a public official who is authorized to make an authentic deed whose authority has been determined by law, in fact there are not a few notaries who commit violations or crimes in making a deed so as to result in the emergence of criminal acts, it can be seen in the decision of the Padang District Court Number 535 / Pid.B / 2013 / PN.Pdg, in this case the notary public commits an act of forgery so that the notary is liable to criminal liability against him. This writing aims to review and analyze the legal consequences of the deed which in the process of making that contain elements of forgery and analyze criminal liability against a notary in the Padang District Court's decision No. 535 / Pid.B / 2013 / PN.Pdg. the results of this paper show that the legal consequences of the deed which in the process of making it contain elements of forgery can be canceled, the cancellation of a deed is a sanction against legal actions that contain elements of juridical defects (causes of cancellation) and also has no legal consequences since the cancellation of parties referred to in the deed. The criminal liability against the notary public in the decision of the Padang District Court Number 535 / Pid.B / 2013 / PN.Pdg, has fulfilled both elements in terms of the ability to be responsible and errors, and the absence of forgiving reasons, all three elements have been fulfilled so that the legal notary as the defendant can be held liable for criminal action against him.
Fight Against Doping: Experience of Ukraine and European States
Authors: Reznik Oleg , Muzychuk Oleksandr , Andriichenko Nadiia , Yakushchenko Yuliia , Korzh Svitlana
Published: March 2020

The article deals with the study of the anti-doping experience of Ukraine and European countries. It considers a number of doctrinal and regulatory approaches to the understanding of doping and anti-doping rule violations and, accordingly, the importance of combating such phenomena. The article examines the provisions of international acts regulating the list of prohibited substances, doping testing, the application of sanctions for anti-doping rule violations, and formulates the conclusion on the need to improve the list of prohibited substances, which currently hinders the effectiveness of anti-doping measures. It focuses on the criminal law of Ukraine, Hungary, Estonia, Finland, Germany, Poland, Italy, and Spain, which provides for the criminal liability for doping, including its illegal production, trade, appointment, use, and forcing other persons to use it. The article describes the peculiarities of a unique approach to legal liability for doping in Austria and France, where the specified actions are regarded as fraud. The article establishes the necessity of introducing changes to Article 323 of the Criminal Code of Ukraine to improve the fight against doping in Ukraine and the expediency of harmonizing the provisions of the national legislation of Ukraine and European states with the international rules in terms of the definition of doping and the list of prohibited substances.
STUDYING SOME CLINICAL AND PARACLINICAL CHARACTERISTICS OF POSMATURE BABIES CARED IN NICU AT HUE UNIVERSITY HOSPITAL
Authors: Nguyen Thi Kieu Nhi
Published: March 2020

Objectives: 1. Estimating the ratios of clinical and paraclinical signs of post-term newborns hospitalized at Pediatric Department of Hue University Hospital. 2. Identifying the relation between clinical signs and paraclinical signs. Materials and Method: 72 post- term babies < 7 days of life hospitalized at NICU from 2010/5 to 2011/4. Classification of post - term newborn was based on WHO 2003: gestational age ≥ 42 weeks with clinical manifestations: desquamation on press with fingers or natural desquamation, withered or meconial umbilicus, meconial long finger nails (*) or geatational age still < 42 weeks with theses clinical manifestations (*). Data were recorded on a clinical record form. Per-protocol analysis of clinical outcomes was performed by using Medcalc 11.5 and Excell 2007. Analyses used the χ2 test or Fisher's exact test for categorical data; Student's t test was used for continuous data and the Mann-Whitney U test for nonparametric data. Data were presented as means or proportions with 95% CIs. Results: Clinical characteristics: Tachypnea and grasp were main reasons of hospitalisation (48.61%). Poor feeding, vomitting (16.67%). Asphyxia (8.34%). Jawndice (6.94%). Hypothermia < 36.50C (13.89%), fever (13.89%). Tachypnea (59.72%). Bradycardia (1.39%). Poor feeding (11.11%). Hypertonia (9.72%). Paraclinical characteristics: Erythrocytes < 4.5.1012/l (51.39%), Leucocytes 5 – 25.103/mm3 (81.94%), Thrombocytes 100- 400.103/mm3 (94.44%). Hemoglobinemia < 10mg/l (67.61%). Maternal characteristics: Menstrual cycles regular (75%). Primiparity (75%). Amniotic volume average (70.42%), little (29.58%). Aminiotic liquid clair (62.5%), aminiotic liquid yellow (4.17%), aminiotic meconial liquid (33.33%). Maternal manifestation of one of many risk factors consist of genital infection; urinary infection; fever before, during, after 3 days of birth; prolonged delivery; medical diseases influence the foetus (75%). The relation between clinical signs and paraclinical signs: There was significantly statistical difference: between gestationnal age based on obstetrical criteria and amniotic volume on ultrasound (p < 0.05); between birth weight and glucosemia p < 0.02). There was conversional correlation of average level between erythroctes number and respiratory rate (r = - 0.5158; p < 0,0001), concordance correlation of weak level betwwen leucocytes number and respiratory rate r = 0.3045; p = 0.0093). Conclusion: It should made diagnosis of postterm baby based on degree of desquamation. The mother who has menstrual cycles regular is still delivered of a postterm baby. A postterm baby has the individual clinical and paraclinical signs.
RESEARCH ON CLINICAL MANIFESTATIONS AND AEROBIC BACTERIA OF QUINSY IN HUE CENTRAL HOSPITAL AND HUE UNIVERSITY HOSPITAL
Authors: Truong Kim Tri , Nguyen Tu The , Vo Lam Phuoc
Published: March 2020

Objectives: To identify the paraclinical and clinical mannifestations, aerobic bacteria and antibiogramme of quinsy. Materials and methods: Cross-sectional study was conducted upon 37 patients with quinsy at Hue Central hospital and Hue University Hospital. Results: Clinical and paraclinical symtoms: odynophagy 100%, dysphagy 91.9%. Having treatment with antibiotics before hospitalization 67.6%. White blood cells >15.109/l (54.1%). Positive bacteria culture is 48.6% in which streptococcus α hemolytic 57.9%, staphylococcus aureus 10.5%, streptococcus pneumoniae 10.5%. Antibiogramme: Sensitization: Gentamycin 100%, vancomycin 100%, cefuroxim 100%, ciprofloxacin 80%.Resistance: Erythromycin 60%, ampicillin 41.7%, cefalexin 40%, tetracyclin 40%, ceftriaxon 30.8%.Consclusions: The priority of antibiotic prescription for quinsy should be based on the frequency of bacteria found in bacteria culture and depending on antibiogramme to choose appropriate antibiotics.
PREDICTING VALUE OF LEFT ATRIAL APPENDAGE THROMBUS IN NONVALVULAR ATRIAL FIBRILLATION PATIENTS BY CHADS2 AND CHADS2-VAS’SCORE AND BY TRANSTHORACIC ECHOCARDIOGRAPHIC PARAMETERS
Authors: Bui Thuc Quang , Vu Dien Bien , Pham Nguyen Son
Published: March 2020

Objectives: To evaluate size and function of left atrium and left atrial appendage (LAA) by using transthoracic and transesophageal echocardiography in nonvalvular atrial fibrillation (NVAF) patients. Method: 127 NVAF patients (mean age 65,8 ± 10,0 years) were assessed by using CHADS2 and CHADS2-VAS score, transthoracic and transesophageal echocardiographic parameters. Results: CHADS2 ≥3, CHADS2-VAS ≥ 4 and LAVI ≥ 38ml/m2, diagnosis of LAA thrombus has been expected in turn with Se=67% and Sp=70%, Se=67% and Sp=71% and Se=80% and Sp=60%; With LEVF/LAVI ≤1,5, risk of LAA thrombus was OR=13,3; 95% CI (1,8 – 98,5) with p=0,001. Conclusion: CHADS2, CHADS2-VAS, LAVI and ratio LVEF/LAVI are predictors of LAA thrombus in NVAF patients.
Key words: CHADS 2, CHADS 2 -VAS, left atrial appendage thrombus, thromboembolism, nonvalvular atrial fibrillation
THE OUTCOME OF EXTRACORPOREAL SHOCK WAVE LITHOTRIPSY IN MANAGEMENT OF RESIDUAL KIDNEY STONES AFTER THE FIRST TREATMENT OF THE UPPER URINARY TRACT CALCULUS
Authors: Nguyen Khoa Hung , Le Dinh Khanh , Le Dinh Dam , Nguyen Truong An
Published: March 2020

Introduction: The aim of this study is to assess the efficiency of extracorporeal shock wave lithotripsy (ESWL) in the treatment of residual kidney stones after the first treatment of the upper urinary tract calculus. Patients and Methods: 110 patients with residual kidney stones were treated with a MZ.ESWL.VI lithotripter. They were analyzed with regard to stone size, number of stones, number of ESWL sessions, retreatment rates, stone free rates. Results: 68,2% of patients became stone free within 3 months after ESWL with the average number of 3,44 sessions of treatment. No complication has occurred during all treatment. Conclusion: ESWL is an effective method in managing the residual kidney stones after the first treatment of the upper urinary tract calculus.
STUDY ABOUT THE EFFECTIVENESS OF ATORVASTATIN AND ASPIRIN COMBINATION IN ANTI-INFLAMMATORY IN PATIENTS WITH ACUTE CEREBRAL INFARCTION
Authors: Le Chuyen , Le Thi Bich Thuan , Ho Dien Tuong
Published: March 2020

Background: The relationship between effective therapy of Atorvastatin+Aspirin in patients with acute cerebral infarction and inflammatory factors hs-CRP, fibrinogen. Materials and Methods: Clinical research trials and longitudinal follow-up, 66 patients with acute cerebral infarction treated at General-endocrinology internal Department-Hue University Hospital. Data were processing by conventional statistics methods and SPSS 15.0. Results: i) The concentration of hs-CRP, serum fibrinogen in patients with acute cerebral infarction increased very high: hs-CRP concentration was 6.46±4.49mg/L; fibrinogen was 4.59±1.52g/L. There was a close correlation between hs-CRP and fibrinogen at hospitalization (r=0.5055; p<0.001); moderate positive correlation between hs-CRP with the size of acute cerebral infarction at hospitalization (r=0.3775; p<0.01) and between fibrinogen with NMN the size of acute cerebral infarction (r=0.3343; p<0.01). ii) The anti-inflammatory effect of Atorvastatin and aspirin combination versus aspirin alone: +The difference of the hs-CRP, fibrinogen concentration at the hospital and after 1 month of treatment with Atorvastatin+Aspirin was (paired t 6.16; p<0.01) and (paired t 6.51; p<0.01), respectively. In the group treated with alone Aspirin, hs-CRP levels was (paired t 3.12; p<0.01) and fibrinogen was (paired t 4.93; p<0.01). + Significant anti-inflammatory effect of the combination treatment group compared with the treatment group alone: difference of concentration of hs-CRP between the two groups (1.60±0.65 vs. 4.11±2.54mg/l) with paired t -3.06 and p<0.05; difference of fibrinogen concentration (2.80±0.93 vs. 3.30±0.73g/l) with paired t -2.41 and p<0.05. Conclusion: Patients with acute cerebral infarction treated by Atorvastatin+Aspirin combination have significant effectiveness in reducing the concentration of inflammatory factors hs-CRP, fibrinogen compared with aspirin therapy alone.
HE EFFECTIVENESS OF ELECTROHYDRAULIC LITHOTRIPSY IN THE MANAGEMENT OF RE-OPERATIVED BILIARY LITHIASIS
Authors: Le Manh Ha
Published: March 2020

Objective: To evaluate the effectiveness of electrohydraulic lithotripsy in the treatment of re-perated biliary lithiasis. Materials and Methods: Consist of 108 patients of recurrent biliary lithiasis, underwent diagnosed and re-perated by electrohydraulic lithiotripsy during open surgery or post-operative through a T-tube from january 2005 to may 2011 at Hue Central Hospital. Results: Age average 47.2 ± 6.4 (31-78), rate female/male 1.77/1. Jaundice 42.86%, hepatomegaly 19.44%, fever 66.6%, white blood cell uper 10.000/ml 61.12%, hyperbilirubinemia 88.89%, hight transaminase level 47,28%. Intraoperative complications 19.44%, common post-operative complications 26.8% and not operative mortality. Complete clearance of stones by open surgery accounted for 77.78%, the times of average electrohydraulic lithiotripsy for a patient is 2.19 times. Conclusion: Electrohydraulic lithotripsy in the the treatment of re-perated biliary lithiasis is highly effective and safe with less complication.
ANTIBIOTIC-RESISTANCE OF HELICOBACTER PYLORI: EPIDEMIOLOGY DIAGNOSIS AND TREATMENT
Authors: Dang Ngoc Quy Hue , Tran Van Huy
Published: March 2020

Successful eradicative treatment of H.pylori will reduce the recurrence rate of peptic ulcer disease and the risk of gastric cancer. In our country, the indication of antibiotics for both H.pylori-induced and non-H.pylori-induced diseases has been so available that it has increased H.pylori antibiotic resistance which decreased the efficacy of H.pylori treatment. Some national researches have shown that the rate of H.pylori resistance to Clarithromycin is higher than 20%. For H.pylori-infected patients in whom two empirical regimens fail to eradicate H.pylori, it is necessary to perform culture and antibiogram so that doctors will choose which treatment regimen is suitable for them. Among the H.pylori antibiotic susceptibility testing, the Epsilometer test is both less effort and accurate. H.pylori treatment should be not only standardized and updated according to Maastricht Consensus IV-2012 but also strengthened the management of key antibiotics in H.pylori treatment.
INVESTIGATION HOMOCYSTEIN, CRP SERUM IN TYPE 2 DIABETES PATIENTS IN DANANG CITY
Authors: Nguyen Huu Quoc Nguyen , Pham Thu Van
Published: March 2020

Background: Diabetes is a common chronic glucide metabolic disorder, in which diabetes type 2 is account for a high proportion. Homocystein and CRP play a crucial role in metabolic disorder in type 2 diabetes.
Objective:
1. To Identify serum Hcy, CRP concentration in diabetic type 2 patient.
2. To determine the relationship between serum Hcy, CRP concentrations and some others biochemistry indexes in diabetes type 2 patients.
Methods: a cross-sectional was conducted in 55 patients with type 2 diabetes, 30 patients with impaired glucose tolerance who did not receive any treatments and 35 healthy people with the same age, Serum Hcy, CRP concentrations were determined by immunofluorescence method.
Results: in control group: The serum Hcy and CRP concentrations were: 7,7 (µg/ml) and 0,2 ± 0,21 mg/dl; The serum Hcy and CRP concentrations in diabetic type 2 patients were 12,8 ± 3,08 (µg/ml) and 0,5± 0,47mg/dl. There has been a correlation between Hcy concentration with lipid criteria such as cholesterol, triglyceride, LDL-C, fasting glucose, and HbA1C. There was also a strong correlation between Hcy and CRP concentration (p<0,001).
Conclusion: There was an increase in Hcy and CRP average concentration in patients with diabetic type 2
EVALUATION OF RISK FACTOR CHRONIC OCCLUSIVE ARTERIAL DISEASE OF LOWER EXTREMITY
Authors: Le Quang Thuu
Published: March 2020

Objectives: We research risk factors of chronic occlusive arterial disease of lower extremity.
Subjects and methods: From 05/2010 to 04/2012, prospective study at Department of Thoracic and Cardiovascular Surgery of Hue Centre hospital, we have performed 49 patients in 30 males and 19 females from 33 to 92 ages, who were treated chronic occlusive arterial disease of lower extremity.
Results: Majority of patients came to hospital with severe condition in grade III and IV according to Leriche-Fontain standards (27.12% and 66.1%). All patients incomed, expect the unmodifiable risk factor (as age, sex), we found socialty risk factor remarable (as hypertension 51.1%, smoking 18.36%, diabetes 10.2%, high cholesterol level 4.08%.
Conclusions: Expect the unmodifiable risk factor, we found a the most striking association with hypertension, smoking, diabetes, high cholesterol level.
DEVELOPING VIRTUAL ANATOMY SOFTWARE FOR ANATOMICAL TEACHING
Authors: Tran Duc Lai , Le Dinh Van , Nguyen Huu Tri , Le Dinh Dam , Le Van Dau
Published: March 2020

Objectives: Developing software for practice and assessement of the anatomy of the thorax and abdomen.
Main contents and Method: Development of the software will include the following steps: Dissection of a male cadaver at the anatomy department of the Hue College of Medicine and Pharmacy; Taking pictures of each stage of dissection; Collection of images from other sources; Use of Macromedia Authorware software for development of software for practicing and assessing the anatomy of the thorax and abdomen.
Results: Our goal is to have software of 414 MB size, and when installed will have a directory entry of size 477MB containing 3 programs files. Overall, will contain: 497 pages, with each page containing an image and description of anatomical structures of the thoracic wall, lungs, heart, mediastinum, abdominal wall, inguinal canal, peritonial cavity, stomach, spleen, liver, intestines, pancreas, kidney and adrenal gland, and also male and female pelvis. 13 3D videos for the organs and structures of the thoracical and abdominal cavities. 100 single choice quesitons for the organs and structures of the thoracic and abdominal cavities. The software will be very easy to use. It will be useable for any area of medical specialty.
THE FORATION, DEVELOPMENT AND RESULTS OF RADIOISOTPE’S APPLICATION TO MEDECINE (NUCLEAR MEDECINE) IN VIETNAM
Authors: Phan Sy An
Published: March 2020

Objectives: Presentes the beginning, historical development of radioisotope using and it’s results in Vietnam.
Subjects and Methods: The report is focused on some valuable and helpful studies such as functional tests, myocardial perfusion scintigraphy, bone, thyroid, kidney… scintigraphy by SPECT for diagnosis.
Results: Introduces a new aproach of development and prospect for the NM specialty in near future given in the Vietnam governmental strategy of peaceful using atomic energy in health care sector.
Conclusion: The results of using modern technology PET/CT in especially oncology are showned. Key words: Nuclear medicine
MORPHOLOGICAL CHARACTERISTICS AND SOME OF CHEMICAL PHYSICAL INDICATORS OF CURCULIGO: A VALUABLE MEDICINAL PLANT
Authors: Phan Van Tan , Le Thuong , Le Van Trong
Published: March 2020

Objectives: Researching morphological characteristics and some chemicophysical indicators of Curculigo.
Subjects and Methods: Curculigo in Gia Lai province and KonTum.Methods: To carry out field research (distribution, morphological characteristics, condition of the site). Location: The national sanctuary Kon Ka Kinh, Kbang district, Gia Lai province, and Mang Den, Kon Plong district, Kon Tum province.
Results:
(i) The scientific name is Curculigo sp, Hypoxidaceae group, Asparagales set, Monocotyledonae class;
(ii) Curculigo sp is distributed in narrow site, only Đak Roong commune, Kbang district, Gia lai province;
(iii) Curculigo sp is valuable and rare materials.
Conclusion: Curculigo sp is a rare and valuable materials in Gia Lai and Kon Tum, so it must be preserved and developed.
SEVERITY AND QUALITY OF LIFE AMONG PREGNANT WOMEN SUFFERING NAUSEA AND VOMITING DURING THE FIRST HALF OF PREGNANCY
Authors: Nguyen Thi Bich Ngoc , Nguyen Vu Quoc Huy
Published: March 2020

Objectives:
1. To measure the severity of nausea, vomiting and retching among pregnant women during the first half of pregnancy by using the “Rhodes Index of Nausea, Vomiting and Retching” (INVR).
2. To identify associated factors and assess the quality of life of these women using the “Health-Related Quality of Life for Nausea and Vomiting during Pregnancy” (NVPQOL) questionnaire.
Materials and methods: 97 pregnant women with gestational age ≤ 20 weeks, identified by LMP or ultrasound results from 1st trimester, having nausea and/or vomiting during the last week before the clinic visit at Department of Obstetrics & Gynecology, Hue Central Hospital during the period from 1st April 2011 to 30th March 2012. The “Rhodes Index of Nausea, Vomiting and Retching” (INVR) has been used to measure the severity of nausea, vomiting and retching; “Health-Related Quality of Life for Nausea and Vomiting during Pregnancy" (NVPQOL) questionnaire was used to assess the quality of life of these women.
Results: Rate of asymptomatic subjects was 4.1%, mild level was 59.8%, moderate level was 24.6%, great level was 8.4%, and severe level was 3.1%. Results from quality of life scale showed average mark of physical symptoms and aggravating factors (PSAF) of 41.8±12.63; emotions (E) of 37.8±8.53; fatigue (F) of 17.6±6.34, and limitations (L) of 50.8±13.95; overall result of 147.2±39.12 - at acceptable level.
Conclusions: Special attention and care should be paid to the group of women experiencing great and severe nausea and vomiting (11.5). Quality of life assessed by Health-Related Quality of Life for Nausea and Vomiting during Pregnancy questionnaire is proportionally influenced by the severity of nausea and vomiting.

Key words: nausea and vomiting, pregnant, INVR, NVPQOL
EVALUATION OF LEFT VENTRICULAR DYSFUNCTION BY ECHO-DOPPLER IN CONTINUOUS AMBULATORY PERITONEAL DIALYSIS PATIENTS
Authors: Vo Tam , Hoang Viet Thang
Published: March 2020

Backgrounds: Cardio-vascular disorders contribute to mortality in patients suffering end stage kidney disease with peritoneal dialysis. Objectives:
(1) To determine the rate of left ventricular systolic dysfunction and left ventricular diastolic disfunction in end-stage chronic renal failure patients treated by CAPD;
(2) To evaluate the correlation between left ventricular systolic dysfunction and left ventricular diastolic disfunction
Patients-Methods: A cross-sectional design on 30 ESRD patients treated by CAPD at Department of Nephrology- Hue central Hospital were selected for this study from 1/2010 to 6/2011.
Results: Stydying left ventricular function in 30 hemodialysis patients in Hue central Hospital by Echo - Doppler, we found 53.33% of cases with left ventricular systolic dysfunction and 56.67% of such patients with left ventricular diastolic dysfunction. Most of these cases (88.23%) had mixed dysfunction.
Conclusions: There were relations between left ventricular dysfunction and anemia (Hemoglobinemia), between left ventricular dysfunction and the time of treatement by hemodialysis, but it was not related to hypertension.

Key words: left ventricular, Echo – doppler, hemodialysis
DISSOLUTION ENHANECEMENT OF AN ANTIHYPERTENSIVE AGENT BY SOLID DISPERSION
Authors:   Ha Lien Phuong Tran, Truong Dinh Thao Tran, Do Thai Ngan Le, Ngan Trieu Yen Dang,  Thanh Thao Ly, Thi Thuy Duong Pham, Van Toi Vo
Published: March 2020

Purposes: To evaluate dissolution enhancement of IS, a poorly water-soluble drug, by PEG 6000-based solid dispersion and investigate mechanism of dissolution enhancement from the solid dispersion. Methods: Solid dispersion was prepared by melting method. Dissolution test was performed at pH 6.8. Powder X-ray diffraction (PXRD) and Fourier transform infrared spectroscopy (FTIR) were used to investigate the drug crystallinity as well as the interaction between drug and polymer. Results: Dissolution rate of IS from the solid dispersion was significantly increased at pH 6.8 as compared to the pure drug. Drug crystallinity was reduced. FTIR showed the interaction between polymer and IS in the solid dispersion. Conclusions: PEG 6000 was successfully used to increase the dissolution of IS. Moreover, mechanism of the dissolution enhancement was fully explained in the study.

Key words: poorly water-soluble drug, dissolution, solid dispersion.
VALUE OF FRACTIONAL ANISOTROPY IN THE DIFFUSION TENSOR IMAGING ON GLIOMA GRADING
Authors: Nguyen Van Dinh , Hoang Minh Loi
Published: March 2020

Background: Our purpose was to determine the value of FA in preoperative predicting the histological grade of glioma. Materials and methods: Descriptive study with 32 patients in Da Nang Hospital, from 01/2012 to 6/2013, with histological verified gliomas. DTI was performed to study the relationship between FA value and grade of gliomas. Results: Median FA of tumor border and median FA of ratio tumor border/normal white matter of the contralateral hemisphere were 0.234 + 0.200 and 0.721 + 0.608 for grade 2 versus 0.147 + 0.053 and 0.387 + 0.138 for grade 3 (p=0.038 and 0.006). Conclusion: FA of tumor border is valuable for preoperative predicting the histological grade 2 and 3 of glioma.

Key words: Fractional anisotropy (FA), Glioma, Histological grade, MR diffusion tensor imaging (magnetic resonance diffusion tensor imaging).
RESEARCH FINDINGS INFECTION FASCIOLIASIS BY TECHNICAL ENZYMES LINKED IMMUNOSORBENT (ELISA)
Authors: Dang Van Phu , Tran Thang , Nguyen Chi Thanh , Tran Thi Phuong Nhi , Nguyen Viet Duy , Le Thi Nhan , Thai Thi Thuy Van , Nguyen Thi Tu Anh
Published: March 2020

Introduce: Fascioliasis is an infection common in animals,particularly sheep and cattle, and is widespread around the world. The disease can be transmitted through food to Humans where it affects the liver. It is also known as “common liver fluke infection”. Material and method: Include 326 person with suspected infection of fasciolasis, and recived ELISA from 4/2012 to 6/2013 at Hue Central Hospital. Result: The rate of ELISA positive liver for 31.3%, men 24.4%, women 38.3%, rural areas accounted for 36.8%, Farmer group 36.2%. Conclusion: Prevalence of Fasciolisis with symptoms suggestive in clinically is 31.3%. Main source of contamination due to people eating aquatic plants.

Key words: Fascioliasis, ELISA
EVALUATION OF ELASTIC PROPERTIES OF THE ASCENDING AORTA IN MALE TOBACCO ADDICTS BY ECHOCARDIOGRAPHY
Authors: Tran Minh Hoa , Nguyen Thi Thuy Hang
Published: March 2020

Background: Cigarette smoking causes endothelial cell injury, loss of smoothness, elasticity, it would be easy to form plaques in the endothelium. Etude of elasticity of ascending aorta by echocardiography in male smokers contribute to the assessment of vascular changes through indices such as aortic strain, aortic stiffness, aortic distensibility. Aim: was to estimate the effects of chronic smoking on the elastic properties of the ascending aorta. Material and Methods: this study was carried on 180 male subject, 90 smokers, mean age 37.56 ± 7.31 and 90 healthy male non-smokers with similar age. They are all under echocardiography to measure systolic aortic diameter and diastolic aortic diameter, determine the indexes such as: aortic strain, aortic stiffness, aortic distensibility and blood pressure simultaneously. Results:
strain index and aortic distensibility is significantly lower in smokers than the control group, whereas stiffness index in smokers is higher than the control group with p <0.001. Conclusions: In tobacco addicts, smoking change the elasticity of the aorta, so it is a predictor of cardiovascular risk factors.

Keywords: Tobacco addicts, aortic elastic properties, echocardiography
THE PHYSICOCHEMICAL PROPERTIES OF GLUCOMANNAN FLOUR OF AMORPHOPHALLUS PAEONIIFOLIUS CULTIVALED IN THUA THIEN HUE
Authors: Nguyen Thi Hoai , Tran Thi Van Thi , Le Trung Hieu , Vo Thi Mai Huong
Published: March 2020

Background: There are many beneficial effects such as reducing the risk of obesity, diabetes, hyperlipidemia and hypercholesterolemia from Amorphophallus sp. This reports are research results of physicochemical properties of glucomannan flour from tubers of Amorphophallus paeoniifolius cultivated in Thua Thien Hue. Materials: Glucomannan flour from tubers of Amorphophallus paeoniifolius (Dennst) Nicolson – Araceae cultivated in Thua Thien Hue. Method: Identify the quantity and physicochemical properties by many methods such as using enzymes, chemistry, physical chemistry, spectroscopic methods, laser analysis. Results: Identified starch and glucomannan quantity, physicochemical properties and indicators of microbiological of glucomannan flour. Conclusion: From the achieved results set up quality standards of glucomannan flour from tubers of Amorphophallus paeoniifolius cultivated in Thua Thien Hue.

Key words: Glucomannan, starch, β-amylase.
EVALUATE THE EFFECTIVENESS OF INITIAL IMPLEMENTATION OF UNTRASOUND-GUIDED BRACHIAL PLEXUS BLOCKAGE
Authors: Nguyen Viet Quang
Published: March 2020

Objective: To evaluate the effectiveness of initial implementation of ultrasound-guided brachial plexus blockage. Subjects and methods: In 30 patients undergoing upper limb surgery from arm to hand with ASA I, II, aged from 16 to 81 at Hue Central Hospital from 8/2011 to 2/2012. The untrasound-guided interscalene brachial plexus blockage was performed with 20 ml of 1% lidocaine mixed with adrenaline 150mcg. The sensory and motor evaluated by Hollmen score, including paresthesia, the onset and duration of sesorry, motor blockage, the success rate and and complications were noted. Result: The mean onset of sensory and motor blockage were 5.30±1.53min, 17.76±3.58min. Mean duration of sensory and motor blockage were 123.46±12.64, 152.33±15.41. The success rate was 96.70% good, 3.30% quite good, no failures and major complications occurred in the study group. One cas has broken nerve sheath besause of too strong pump. Conclusion: The untrasound-guided interscalene brachial plexus blockage lead to a high success rate (96.70% good, 3.30% quite good).

Key words: Initial implementation, ultrasound-guided interscalene brachial plexus blockage.
El fútbol de los que sobran: apuntes sobre la necesidad de nuevas concepciones éticas en relación al desarrollo humano de los deportistas de élite
Authors: Santome Sánchez Aldo Alesandro
Published: March 2020

En el presente artículo se busca reflexionar sobre el fenómeno del fútbol en la actualidad, analizándolo no solo como una actividad deportiva, sino como un espectáculo global y como una de las industrias que más dinero circula. En medio de ese contexto, hacemos hincapié en la situación de los futbolistas de élite, quienes, debido a la visión mercantilista que proponen varias instituciones deportivas, son vistos como las principales herramientas de obtención de riqueza, obviando su desarrollo personal.
La objeción de conciencia del personal médico frente al aborto terapéutico regulado en el Protocolo de Aborto Terapéutico
Authors: Pérez Dávila Belú Fiorella
Published: March 2020

El Protocolo de Aborto Terapéutico (PAT), vigente desde el 2014, regula el procedimiento para la ejecución de abortos terapéuticos a nivel nacional. Establece una lista abierta de entidades clínicas para su acceso, bajo el Consentimiento Informado de la gestante y sin incluir los derechos de su hijo.  Esta norma genera en el profesional médico la obligación de ejecutar abortos, lo cual puede contradecir los preceptos de su conciencia sobre el respeto indiscriminado de toda vida humana, restringiendo su derecho constitucional a la libertad de conciencia. En el presente artículo, analizamos el contenido de dicha libertad y el derecho a la Objeción de Conciencia, así como la coherencia entre el PAT y el Art. 119 del Código Penal (CP), para determinar si con esta norma tiene lugar la Objeción de Conciencia (O.C) del profesional médico a la ejecución de dicho aborto, por colisionar con su convicción profunda de respetar a toda vida humana, con independencia de su etapa de desarrollo humano.
Propuesta de fortalecimiento de vínculos paterno-filiales en las futuras generaciones en relación a las nuevas tecnologías de la información y comunicación
Authors: Gálvez Manrique Daniela
Published: March 2020

En la actualidad el uso de las nuevas tecnologías de la información y comunicación cobran mayor relevancia, también dentro del ámbito familiar y bioético, las cuales si no son utilizadas de manera adecuada pueden generar diversas dificultades. El objetivo de esta investigación fue diseñar una propuesta de fortalecimiento de los vínculos paterno-filiales de las futuras generaciones en convivencia con las nuevas tecnologías de la información y comunicación. Para lo cual nos propusimos explicar los fundamentos antropológicos de la persona y la familia, los elementos esenciales que fortalecen los vínculos paterno-filiales y la definición de conceptos a partir de la revisión bibliográfica existente sobre la influencia de las nuevas tecnologías de la información y comunicación en niños hasta los 10 años que son hijos de padres millennials. El paradigma de esta investigación ha sido teórico, el abordaje metodológico cualitativo y el tipo de investigación fue documental. Para la recolección de datos, se utilizó como instrumentos la observación documental, además de notas bibliográficas, textuales, síntesis y de resumen, que permitieron organizar de manera adecuada la información obtenida de las diferentes fuentes impresas y digitales: libros, revistas y tesis. Entre los criterios éticos consideramos el respeto a la persona, búsqueda del bien común, de la justicia, y el respeto a la familia; en cuanto a los criterios de rigor científico están incluidos: sustentación del tema en estudio en la antropología de la persona y la familia, enfoque científico-humanista de manera explícita, buscando siempre el respeto por la persona y la neutralidad en la selección de las fuentes de información. Finalmente se obtuvo como resultado de la investigación una propuesta que abarca tres puntos claves: importancia de la educación continua en las escuelas para padres donde refuercen sus conocimientos sobre estos temas y cobren conciencia sobre aquello que están haciendo mal o podrían mejorar, la trascendencia de la comunicación entre padres e hijos junto con la necesidad de la desconexión digital periódica y la importancia de los momentos de compartir familiar; y la educación de la afectividad, lo cual se verá reflejado en el desarrollo emocional saludable de los niños.
Criterios teóricos y prácticos que orientan el uso de dispositivos móviles en la comunicación familiar con adolescentes
Authors: Gómez Ibañez Janett Melita
Published: March 2020

En la base del contexto actual de uso de dispositivos móviles por parte de adolescentes, surge la necesidad de establecer los criterios teóricos y prácticos para promover la comunicación familiar partiendo de esta realidad. Desde un estudio cuanti - cualitativo, descriptivo e interpretativo, se ha identificado teorías que apoyan la inserción de estos dispositivos, así como las que califican su uso como objetos de conflicto e intrusión familiar. De este modo, se logró clasificar su utilidad y funcionalidad así como el abuso y dependencia. Se concluyó que, en la etapa temprana adolescente existe una moderada extensión de uso que se incrementa progresivamente con la edad, y la necesidad del diseño de propuestas que orienten a las familias acerca de las ventajas y riesgos que el uso de estos dispositivos generan
Enfermedades ocupacionales del personal de enfermería y su relación con las condiciones de trabajo. Hospital Provincial Docente Belén de Lambayeque.2018
Authors: Ojeda Mino Miguel Angel , Lázaro Alcántara Elaine
Published: March 2020

Este estudio tuvo por objetivo de determinar la relación que existe entre las enfermedades ocupacionales del personal de Enfermería y las condiciones de trabajo en el Hospital Provincial Docente Belén de Lambayeque. El tipo de investigación fue cuantitativo de correlación corte transversal. La muestra estuvo constituida por 127 trabajadores de enfermería, de nivel profesional y técnico, del Hospital Provincial Docente Belén Lambayeque. Se empleó, el cuestionario diseñado y validado por Blanch JM, Sahagún M y Cervantes G (2010), evaluándose las condiciones de trabajo: el factor organización y método, conformado por la escala de organización y método: regulación, y la escala organización y método: desarrollo y el factor organización y entorno que está conformado por la escala de organización y entorno material y la escala organización y entorno social. Entre las enfermedades ocupacionales y las condiciones de trabajo, no existe una relación directa, obteniéndose una X2=1.235; gl=2 y p=0.539. Así mismo, se determinó que las enfermedades más frecuentes son: la lumbalgia, gastritis y síndrome de hombro doloroso, por otro lado, en las condiciones de trabajo en la escala de organización y entorno material lo califican como malo en un 48.8%. Finalmente se determinó que no existe una relación directa entre las enfermedades ocupacionales y las condiciones de trabajo.

Palabras clave: Enfermedades Ocupacionales, Condiciones de trabajo, Personal de Enfermería.
Enfermería profesión que innova y da esperanzas
Authors: Cervera Vallejos Mirtha Flor
Published: March 2020

En un recorrido panorámico tanto por las instituciones donde se forman y trabajan los profesionales de enfermería como en los servicios hospitalarios y las comunidades en las cuales prestan servicios, evidenciamos el despliegue competente de conocimientos y habilidades para salvaguardar la vida y enseñar a salvaguardarla. Esta es la exigencia fundamental para un futuro próximo asegurar profesionales debidamente formados para esta función. Pues, servir al cuidado y enseñar cómo realizarlo forman parte de la constante preocupación por quienes dirigen la enfermería en todos los tiempos, más aún hoy.

Palabras clave: Enfermería, cuidado, esperanza.
Evaluación de la dimensión informacional en la competencia digital de estudiantes universitarios
Authors: Chunga Chinguel Gerardo , Rumiche Chávarry Rocío del pilar
Published: March 2020

La alfabetización digital y la competencia digital son claves hoy para todos los ciudadanos siendo una herramienta indispensable para los estudiantes universitarios, tanto para el aprendizaje como para el desarrollo de la competencia investigativa. El objetivo, de la investigación, es conocer en qué medida la dimensión informacional, que es parte la competencia digital, está adquirida por los estudiantes de esa Universidad. La metodología usada ha sido tipo encuesta, a través de la aplicación de un cuestionario. Los resultados de la investigación es que, a pesar de la importancia, del acceso a la información de calidad para los estudiantes universitarios, el nivel de la mayoría de los estudiantes de la muestra, en cuanto a dominio de la dimensión informacional, está en proceso de lograrlo y una octava parte de ellos, ya ha conseguido dominar la dimensión informacional.
Inteligencia emocional en el sector educativo
Authors: Olivares jiménez Anthuanet , Gamarra Flores Carla Ethel
Published: March 2020

El presente estudio buscó determinar la situación actual del tema inteligencia emocional en el sector educativo realizando una búsqueda de información en artículos y revistas en distintas bases de datos (Science direct, Scielo, Dialnet, Redalyc) utilizando palabras claves en español e inglés: Inteligencia emocional y sector educativo. Después de una depuración con criterios de pertinencia se contó con una muestra de 22 artículos para realizar la investigación. Los resultados muestran que los docentes tienen mayor rendimiento laboral a mayor inteligencia emocional, evitando la afectación del síndrome de Burnout. Mientras que la diferenciación por sexo, tanto en docentes como estudiantes, las mujeres tienen mayor inteligencia emocional. Por otro lado, los estudiantes mejoran en el rendimiento académico al desarrollar su inteligencia emocional. Además se obtiene que los estudiantes con ideas suicidas son los que carecen de habilidades emocionales.
El marco jurídico de la migración en Marruecos
Authors: Mrabti Abdelali
Published: March 2020

A lo largo de la historia, Marruecos se formó a través de una mezcla diversa de las poblaciones de diferentes orígenes, alimentada por sucesivas migraciones, en particular de países con los que este Estado tiene relaciones especiales y antiguas (Francia, España, Argelia o Senegal). Situado en el extremo noroeste del continente africano, Marruecos tiene una localización estratégica en el Mediterráneo como puente entre África y Europa. Su historia como país de emigración es larga, aunque el auge de los flujos de salida se produce en la década de los años sesenta. En la actualidad Marruecos es una encrucijada fundamental de las corrientes migratorias que se dirigen hacia Europa y el principal país de emigración de la orilla Sur del Mediterráneo. Marruecos se convirtió en un país de tránsito y de destino para muchos migrantes de África del Occidental, muchos de los cuales son irregulares.