bluuebunny/crossref_metadata_2025 huggingface dataset:
Sensory neuron differentiation potential of in utero mesenchymal stem cell transplantation in rat fetuses with spina bifida aperta
Authors: Ma Wei , Wei Xiaowei , Gu Hui , Li Hui , Guan Kaoping , Liu Dan , Chen Lizhu , Cao Songying , An Dong , Zhang Henan , Huang Tianchu , Miao Jianing , Zhao Guifeng , Wu Di , Liu Bo , Wang Weilin , Yuan Zhengwei
Published: July 2015

BACKGROUND

In previous studies, we found that the deficiency of sensory and motor neurons was a primary defect associated with the spinal malformation. Upon prenatal treatment of spina bifida through in utero stem cell transplantation in a retinoic acid‐induced spina bifida rat model, we found that the mesenchymal stem cell (MSCs) survived, migrated, and differentiated into cells of a neural lineage. In the present study, we investigated whether the transplanted MSCs had the potential to differentiate into sensory neurons or to protect sensory neurons in the defective spinal cord.

METHODS

Pregnant rats treated with retinoic acid on embryonic day (E) 10, underwent fetal surgery for MSC transplantation on E16. The fetuses were harvested on E20. Immunofluorescence was used to detect the expression of Brn3a protein in the transplanted MSCs and dorsal root ganglion (DRG) neurons in the defective spinal cords. The expression of the transcription factors Brn3a and Runx1 in spinal cords was analyzed using real‐time polymerase chain reaction.

RESULTS

Some of the transplanted MSCs expressed sensory neuron cell specific phenotypes. The expression of Brn3a and Runx1 was upregulated in the defective spinal cords when compared to controls. The percentage of Brn3a‐positive neurons in DRG was also increased after transplantation.

CONCLUSION

Our results indicate that the transplantation of MSCs into the spinal cord could promote the transplanted MSCs and the surrounding cells to differentiate toward a sensory neuron cell fate and to play an important role in protecting sensory neurons in DRG. This approach might be of value in the treatment of sensory neuron deficiency in spina bifida aperta. Birth Defects Research (Part A) 103:772–779, 2015. © 2015 Wiley Periodicals, Inc.
Register based study of anorectal anomalies over 26 years: Associated anomalies, prevalence, and trends
Authors: Godse Alok S. , Best Kate E. , Lawson Anne , Rosby Lucy , Rankin Judith
Published: July 2015

BACKGROUND

Anorectal anomalies are atresias or stenoses of the anal canal and rectum with or without fistulous connections with the bladder, urethra, perineum, or vestibule. The aim of this study was to describe the epidemiology of anorectal anomalies, including associated anomalies, prevalence, and temporal trends.

METHODS

Anorectal anomalies occurring in late miscarriages (>20 gestation weeks), terminations of pregnancy for fetal anomaly (any gestation), stillbirths (≥24 gestation weeks) and live births, delivered from 1985 to 2010, notified to the Northern Congenital Abnormality Survey (NorCAS) were included in this population‐based case series.

RESULTS

There were 278 cases among 892,194 live births. Twenty (7.2%) cases occurred in twin pregnancies and 24 (8.7%) with chromosomal anomalies/genetic syndromes were excluded. There were 234 cases (total prevalence = 2.7, 95% confidence interval [CI]: 2.4, 3.1 per 10,000 live and stillbirths). There was no evidence of a trend in prevalence over time (Chi2 test for trend: p = 0.789). There was a male predominance (70.9%). Of the 234 cases, 167 (71.4%) were live born, two (0.9%) were late miscarriages, seven (3.0%) were stillbirths, and 58 (24.8%) were terminations of pregnancy for fetal anomaly. There was no significant association with maternal age at delivery (p = 0.095). 7.2% of isolated cases (cases with no other congenital anomalies) were diagnosed prenatally.

CONCLUSION

The prevalence of anorectal anomalies in this study is comparable to other case series. There was no evidence of a temporal increase in prevalence. We confirmed a male predominance of anorectal anomalies and no significant association with maternal age. Birth Defects Research (Part A) 103:597–602, 2015. © 2015 Wiley Periodicals, Inc.
Did the notochord evolve from an ancient axial muscle? The axochord hypothesis
Authors: Brunet Thibaut , Lauri Antonella , Arendt Detlev
Published: July 2015

The origin of the notochord is one of the key remaining mysteries of our evolutionary ancestry. Here, we present a multi‐level comparison of the chordate notochord to the axochord, a paired axial muscle spanning the ventral midline of annelid worms and other invertebrates. At the cellular level, comparative molecular profiling in the marine annelids P. dumerilii and C. teleta reveals expression of similar, specific gene sets in presumptive axochordal and notochordal cells. These cells also occupy corresponding positions in a conserved anatomical topology and undergo similar morphogenetic movements. At the organ level, a detailed comparison of bilaterian musculatures reveals that most phyla form axochord‐like muscles, suggesting that such a muscle was already present in urbilaterian ancestors. Integrating comparative evidence at the cell and organ level, we propose that the notochord evolved by modification of a ventromedian muscle followed by the assembly of an axial complex supporting swimming in vertebrate ancestors.
Fluorescence resonance energy transfer for investigation of the interaction of Para Red with serum albumins
Authors: Zhu Lin , Zeng Xiaodan , Zhang Fusheng
Published: July 2015

Para Red (PR) has been isolated from food additives, and shown to be toxic to humans. To facilitate examination of its toxicity, the interaction between PR and serum albumins (SA) was studied using fluorescence quenching and circular dichroism (CD) spectrophotometry. The experiments showed that the fluorescence intensity of serum albumins decreased with increasing concentrations of PR, which resulted from the binding of PR and SA. The binding constant, number of binding sites and thermodynamic parameters were calculated and hydrogen bond and van der Waals interactions were shown to play a key role in the binding process. Competition experiments indicated that PR mainly binds to Trp residues of SA within the site I. As the CD and three‐dimensional spectra revealed, the addition of PR induced a conformational change in SA. Copyright © 2015 John Wiley & Sons, Ltd.
Nucleation temperature‐controlled synthesis and in vitro toxicity evaluation of l‐cysteine‐capped Mn:ZnS quantum dots for intracellular imaging
Authors: Pandey Vivek , Pandey Gajanan , Tripathi Vinay Kumar , Yadav Sapna , Mudiam Mohana Krishna Reddy
Published: July 2015

Quantum dots (QDs), one of the fastest developing and most exciting fluorescent materials, have attracted increasing interest in bioimaging and biomedical applications. The long‐term stability and emission in the visible region of QDs have proved their applicability as a significant fluorophore in cell labelling. In this study, an attempt has been made to explore the efficacy of l‐cysteine as a capping agent for Mn‐doped ZnS QD for intracellular imaging. A room temperature nucleation strategy was adopted to prepare non‐toxic, water‐dispersible and biocompatible Mn:ZnS QDs. Aqueous and room temperature QDs with l‐cysteine as a capping agent were found to be non‐toxic even at a concentration of 1500 µg/mL and have wide applications in intracellular imaging. Copyright © 2015 John Wiley & Sons, Ltd.
Randomized clinical trial of prevention of seroma formation after mastectomy by local methylprednisolone injection
Authors: Qvamme G , Axelsson C K , Lanng C , Mortensen M , Wegeberg B , Okholm M , Arpi M R , Szecsi P B
Published: July 2015

Background

Seroma formation, the most prevalent postoperative complication after mastectomy, is an inflammatory process that is potentially preventable via local steroid administration. This study investigated the effect of local steroid administration on seroma formation.

Methods

This was a double-blind randomized placebo-controlled intervention study of a single dose of 80 mg methylprednisolone versus saline on seroma formation after mastectomy. Patients were further classified according to the surgical axillary procedure: mastectomy with sentinel lymph node biopsy (M + SLNB) or mastectomy with level I–II axillary lymph node dissection (M + ALND). Treatments were administered into the wound cavity via the drain orifice following removal of the drain on the first day after surgery. The primary endpoint was seroma formation; secondary endpoints included the frequency of side-effects and complications.

Results

A total of 212 women scheduled for mastectomy for primary breast cancer were included. After M + SLNB, 32 (46 per cent) of 69 women developed a seroma in the methylprednisolone group, compared with 52 (78 per cent) of 67 in the saline group (P < 0·001). The mean cumulative seroma volume in the intention-to-treat population for the first 10 and 30 days was significantly lower in the methylprednisolone group (24 ml versus 127 ml in the saline group, and 177 versus 328 ml respectively) (P < 0·001). After M + ALND, similar proportions of patients developed a seroma in the methylprednisolone (35 of 37, 95 per cent) and saline (34 of 36, 94 per cent) groups, and methylprednisolone administration had no significant effect on seroma formation. No differences in infection rate were observed.

Conclusion

Methylprednisolone administered into the wound cavity on the first day after M + SLNB exerted a highly significant preventive effect against seroma formation during the next 30 days. This effect was not seen in the M + ALND group. Future studies may clarify whether higher or repeated methylprednisolone doses increase the efficacy.
For Your Bookshelf …
Authors: Mercier Rose
Published: July 2015

Governance coach Rose Mercier gives us an overview of what can be learned from Leading with Intent: A National Index of Nonprofit Board Practices, a recent publication from BoardSource, a US nonprofit dedicated to advancing the public good by building exceptional nonprofit boards and inspiring board service.
A national comparison of biochemistry and molecular biology capstone experiences
Authors: Aguanno Ann , Mertz Pamela , Martin Debra , Bell Ellis
Published: July 2015

Recognizing the increasingly integrative nature of the molecular life sciences, the American Society for Biochemistry and Molecular Biology (ASBMB) recommends that Biochemistry and Molecular Biology (BMB) programs develop curricula based on concepts, content, topics, and expected student outcomes, rather than courses. To that end, ASBMB conducted a series of regional workshops to build a BMB Concept Inventory containing validated assessment tools, based on foundational and discipline‐specific knowledge and essential skills, for the community to use. A culminating activity, which integrates the educational experience, is often part of undergraduate molecular life science programs. These “capstone” experiences are commonly defined as an attempt to measure student ability to synthesize and integrate acquired knowledge. However, the format, implementation, and approach to outcome assessment of these experiences are quite varied across the nation. Here we report the results of a nation‐wide survey on BMB capstone experiences and discuss this in the context of published reports about capstones and the findings of the workshops driving the development of the BMB Concept Inventory. Both the survey results and the published reports reveal that, although capstone practices do vary, certain formats for the experience are used more frequently and similarities in learning objectives were identified. The use of rubrics to measure student learning is also regularly reported, but details about these assessment instruments are sparse in the literature and were not a focus of our survey. Finally, we outline commonalities in the current practice of capstones and suggest the next steps needed to elucidate best practices. © 2015 by the International Union of Biochemistry and Molecular Biology, 43(4):223–232, 2015.
Metabolites identification of Huo Luo Xiao Ling Dan in rat urine by UPLC coupled with electrospray ionization time‐of‐flight mass spectrometry
Authors: Wang Fenrong , Wu Yun , Ai Yu , Bian Qiaoxia , Ma Wen , Lee David Y.‐W. , Dai Ronghua
Published: July 2015

Huo Luo Xiao Ling Dan (HLXLD), a Chinese herbal formula, is used in folk medicine for the treatment of arthritis and other chronic inflammatory diseases. However, the in vivo integrated metabolism of its multiple components remains unknown. In this paper, an ultra‐performance liquid chromatography coupled with quadrupole time‐of‐flight tandem mass spectrometry (UPLC‐Q‐TOF‐MS) method was developed for detection and identification of HLXLD metabolites in rat urine at high and normal clinical dosages. The prototype constituents and their metabolites in urine were analyzed. The mass measurements were accurate within 8 ppm, and subsequent fragment ions offered higher quality structural information for interpretation of the fragmentation pathways of various compounds. A total of 85 compounds were detected in high dosages urine samples by a highly sensitive extracted ion chromatograms method, including 31 parent compounds and 54 metabolites. Our results indicated that phase 2 reactions (e.g. glucuronidation, glutathionidation and sulfation) were the main metabolic pathways of lactones, alkaloids and flavones, while phase I reactions (e.g. hydrogenation and hydroxylation) were the major metabolic reaction for coumarins, paeoniflorin and iridoids. This investigation provided important structural information on the metabolism of HLXLD and provided scientific evidence to obtain a more comprehensive metabolic profile. Copyright © 2015 John Wiley & Sons, Ltd.
Depression and anxiety in patients with and without same‐sex attraction: differences in clinical expression, lifestyle factors, and vulnerability indicators
Authors: Bos Henny M. W. , Boschloo Lynn , Schoevers Robert A. , Sandfort Theo G. M.
Published: July 2015

Background

The aim of this study was to compare clinical expressions (severity and loneliness), lifestyle factors (substance use), and vulnerability indicators (stressful childhood experiences) in patients with any same‐sex attraction versus heterosexual patients diagnosed with depression and/or anxiety disorder. Little is known about this, even though it is now well documented that depression and anxiety are more prevalent among persons with same‐sex attraction.

Method

Data, derived from the Netherlands Study of Depression and Anxiety (NESDA), allowed us to compare patients with a same‐sex (n = 122) and an exclusively opposite‐sex (n = 1658) attraction. Persons with same‐sex attraction included persons who were attracted to both sexes. Data were collected by means of the Composite International Diagnostic Interview and paper‐and pencil questionnaires.

Results

Seven percent of the patients reported any same‐sex orientation. Clinical expression of depression and anxiety did not differ in relation to sexual attraction. Regarding substance use, same‐sex attracted women reported more drug use than heterosexual women (drug use: 16.2% vs. 6.6%, P = 0.003). Regarding stressful childhood experiences, men with any same‐sex attraction reported more sexual abuse during childhood than men with a heterosexual orientation (20.4% vs. 8.5%, P = 0.005).

Conclusions

For women with same‐sex attraction substance use (especially illicit drug use) might be a coping mechanism to deal with existing symptoms or with the minority stressors they have to deal with; for same‐sex attracted men stressful childhood experiences might reflect an aspect of etiology.
Spasticity in multiple sclerosis and role of glatiramer acetate treatment
Authors: Meca‐Lallana Jose Eustasio , Hernández‐Clares Rocío , Carreón‐Guarnizo Ester
Published: July 2015

Introduction

Spasticity is one of the most disabling and difficult‐to‐treat symptoms shown by patients with multiple sclerosis, who often show a suboptimal and unsatisfactory response to classic treatment and new available nonpharmacological alternatives. Due to the progressive nature of this condition, the early management should be essential to improve long‐term outcomes.

Methods

We performed a narrative literature review of the contribution of spasticity to the burden of multiple sclerosis and the potential role of classic disease‐modifying drugs.

Results

Added to the underlying pathophysiology of spasticity, certain external factors and drugs such as interferon may exacerbate the existing condition, hence their awareness is crucial as part of an effective management of spasticity. Furthermore, the evidence for the effectiveness of glatiramer acetate in preventing spasticity in naïve patients and in those switching from interferon should not be ignored.

Conclusions

This literature review proposes the examination of spasticity and the influence of classic disease‐modifying agents on the level of existing condition among the variables to be considered when deciding on therapy for multiple sclerosis in clinical practice.
Global loss of a nuclear lamina component, lamin A/C, and LINC complex components SUN1, SUN2, and nesprin‐2 in breast cancer
Authors: Matsumoto Ayaka , Hieda Miki , Yokoyama Yuhki , Nishioka Yu , Yoshidome Katsuhide , Tsujimoto Masahiko , Matsuura Nariaki
Published: July 2015

Cancer cells exhibit a variety of features indicative of atypical nuclei. However, the molecular mechanisms underlying these phenomena remain to be elucidated. The linker of nucleoskeleton and cytoskeleton (LINC) complex, a nuclear envelope protein complex consisting mainly of the SUN and nesprin proteins, connects nuclear lamina and cytoskeletal filaments and helps to regulate the size and shape of the nucleus. Using immunohistology, we found that a nuclear lamina component, lamin A/C and all of the investigated LINC complex components, SUN1, SUN2, and nesprin‐2, were downregulated in human breast cancer tissues. In the majority of cases, we observed lower expression levels of these analytes in samples' cancerous regions as compared to their cancer‐associated noncancerous regions (in cancerous regions, percentage of tissue samples exhibiting low protein expression: lamin A/C, 85% [n = 73]; SUN1, 88% [n = 43]; SUN2, 74% [n = 43]; and nesprin‐2, 79% [n = 53]). Statistical analysis showed that the frequencies of recurrence and HER2 expression were negatively correlated with lamin A/C expression (P < 0.05), and intrinsic subtype and ki‐67 level were associated with nesprin‐2 expression (P < 0.05). In addition, combinatorial analysis using the above four parameters showed that all patients exhibited reduced expression of at least one of four components despite the tumor's pathological classification. Furthermore, several cultured breast cancer cell lines expressed less SUN1, SUN2, nesprin‐2 mRNA, and lamin A/C compared to noncancerous mammary gland cells. Together, these results suggest that the strongly reduced expression of LINC complex and nuclear lamina components may play fundamental pathological functions in breast cancer progression.
The Relationship over Time between International Adoption and Institutional Care in Romania and Lithuania
Authors: Chou Shihning , Browne Kevin D.
Published: July 2015

International adoption is seen by some as a solution to the large number of children in institutional care. However, our previous findings did not support the notion that international adoption contributes to the deinstitutionalisation of children (Browne and Chou, ; Chou and Browne, ). As our previous study was cross‐sectional, the aim of this study was to investigate the relationship over time in a country that has banned international adoptions (Romania) and a country that has continued the practice (Lithuania). The numbers of children in care and the numbers of adoptions were obtained from government websites and by contacting government departments. A positive correlation was found between institutional care and international adoption in Romania between 1997 and 2012. The findings for Romania indicated that stopping international adoption was not accompanied by an increase in the number of children in institutional care. A reduction in institutional care in Romania only occurred after the ban on international adoption. However, no correlation was found for Lithuania as both practices remained constant between 2000 and 2012. The findings for Lithuania showed that continued international adoption was not accompanied by a reduction in institutional care. Copyright © 2015 John Wiley & Sons, Ltd.

‘To investigate the relationship over time in a country that has banned international adoptions… and a country that has continued the practice’

Key Practitioner Messages

The notion of international adoption being a viable way to reduce the extent of institutional care is not supported by evidence.

The differences in the levels of national income and birth rates cannot always explain the differences in the development of children's services between countries.
Isolation of lung multipotent stem cells using a novel microfluidic magnetic activated cell sorting system
Authors: Zeng Ling , Qiu Lin , Yang Xue‐Tao , Zhou Yin‐Han , Du Juan , Wang Hai‐Yan , Sun Jian‐Hui , Yang Ce , Jiang Jian‐Xin
Published: July 2015

In recent years, more and more research has shown that the lung is an organ of regenerative potential, with several types of stem/progenitor cells undergoing proliferation and differentiation after lung injury and participating the injury repair process. Mouse lung multipotent stem cells (MLSCs) have extensive self‐renewal ability in culture and could differentiate into endothelial and lung epithelial (alveolar epithelial type 1, 2, and Clara) cells in vitro. But the research of MLSCs was limited due to its rarity. In this study, we introduced a novel microfluidic magnetic activated cell sorting system in the isolation of MLSCs. The sorted MLSCs had better viability and purity. They were identified by colony formation efficiency and differentiation ability and they have self‐renewal and differentiation capacities, highlighting their stem cell properties.
ChemInform Abstract: Two Structure Types Based on Si6O15 Rings: Synthesis and Structural and Spectroscopic Characterization of Cs1.86K1.14DySi6O15 and Cs1.6K1.4SmSi6O15.
Authors: Wierzbicka‐Wieczorek Maria , Goeckeritz Martin , Kolitsch Uwe , Lenz Christoph , Giester Gerald
Published: July 2015

Single crystals of Cs1.86K1.14DySi6O15 (I) and Cs1.6K1.4SmSi6O15 (II) are grown by reaction of SmF3 or Dy2O3, DyF3, SiO2, K2CO3, and Cs2CO3 in a MoO3 or MoO3/RbF flux (Pt crucible, 950 °C, 3—6 h; controlled cooling).
ChemInform Abstract: Crystal Structure of a New Hybrid Antimony—Halide‐Based Compound for Possible Non‐linear Optical Applications.
Authors: Ben Rhaiem Tarek , Boughzala Habib
Published: July 2015

Single crystals of the hybrid compound (H2dabco)2 [Sb2Cl10]·H2O are obtained by stirring a mixture of DABCO and SbCl3 in HCl at 353 K followed by slow evaporation of the solvent (25 °C, 2 weeks).
ChemInform Abstract: Crystal Structure of SrGeO3 in the High‐Pressure Perovskite‐Type Phase.
Authors: Nakatsuka Akihiko , Arima Hiroshi , Ohtaka Osamu , Fujiwara Keiko , Yoshiasa Akira
Published: July 2015

Single crystals of the SrGeO3 high‐pressure phase are prepared by hot pressing of the polycrystalline pseudowollastonite SrGeO3 (BN anvil press, 6 GPa, 1223 K, 1 h).
ChemInform Abstract: Syntheses, Structures, and Characterizations of a New Second‐Order Nonlinear Optical Material: Pb2(SeO3)(NO3)2.
Authors: Meng Chang‐Yu , Geng Lei , Chen Wen‐Ting , Wei Ming‐Fang , Dai Kai , Lu Hong‐Yan , Cheng Wen‐Dan
Published: July 2015

The polar compound Pb2(SeO3)(NO3)2 is prepared by hydrothermal reaction of Pb(NO3)2, SeO2, and H2O (autoclave, 200 °C, 4 d, 75% yield).
ChemInform Abstract: Electrochemical Behavior of SiO as an Anode Material for Na‐Ion Battery.
Authors: Shimizu Masahiro , Usui Hiroyuki , Fujiwara Kohei , Yamane Kazuya , Sakaguchi Hiroki
Published: July 2015

Commercial SiO is ball milled and vapor deposited to achieve an active Na‐ion battery thick‐film anode without the need for a binder or conductive additive.
ChemInform Abstract: Synthesis, Crystal Structures, and Physical Properties of the New Zintl Phases A21Zn4Pn18 (A: Ca, Eu; Pn: As, Sb)—Versatile Arrangements of [ZnPn4] Tetrahedra.
Authors: Suen Nian‐Tzu , Wang Yi , Bobev Svilen
Published: July 2015

The new Zintl phases of title are synthesized by reactions of the elements in molten Pb (A:Zn:Pn:Pb = 21:4:18:100; alumina crucibles, 1273 K, 24 h).
ChemInform Abstract: A New Molybdenum Nitride Catalyst with Rhombohedral MoS2 Structure for Hydrogenation Applications.
Authors: Wang Shanmin , et al.
Published: July 2015

Nitrogen‐rich 3R‐MoN2 is prepared by high‐pressure solid state reaction of a 1:2 molar mixture of Na2MoO4 and h‐BN (Mo capsule in anvil press, 3.5 GPa, 773 K) followed by a similar second step, in which the obtained nitride plus unreacted h‐BN is mixed with additional Na2MoO4 in a 1:2 weight ratio.
ChemInform Abstract: A Carbon Nanotube Confinement Strategy to Implement Homogeneous Asymmetric Catalysis in the Solid Phase.
Authors: Hashimoto Kazuki , Kumagai Naoya , Shibasaki Masakatsu
Published: July 2015

A heterogeneous catalyst is produced by self‐assembly of an amide‐based chiral ligand in multiwalled carbon nanotube fibres by addition of erbium(III) isopropylate.
ChemInform Abstract: Light‐Sensitive and Recoverable N‐Heterocyclic Carbene Copper(I) Complex in Homogeneous Catalysis.
Authors: Zhang Guodong , Lang Rui , Wang Wenlong , Lv Hui , Zhao Liyuan , Xia Chungu , Li Fuwei
Published: July 2015

The NHC‐Cu complex CSC is applicable in the oxidation of benzylic alcohols to benzaldehydes (recyclable and reusable at least 4 times) as well as in click reactions.
ChemInform Abstract: Organocatalytic Enantioselective Direct Additions of Aldehydes to 4‐Vinylpyridines and Electron‐Deficient Vinylarenes and Their Synthetic Applications.
Authors: Wang Sinan , Li Xiangmin , Liu Hongwei , Xu Li , Zhuang Jinchen , Li Jian , Li Hao , Wang Wei
Published: July 2015

For example, the nitro group can be easily transformed to diverse functionalities and a chiral pyridine adduct is accessible which serves as key building block in the synthesis of the fibrinogen receptor antagonist L‐734,217 (not shown).
ChemInform Abstract: Enantioselective Bioreductive Preparation of Chiral Halohydrins Employing Two Newly Identified Stereocomplementary Reductases.
Authors: Xu Guo‐Chao , Yu Hui‐Lei , Shang Yue‐Peng , Xu Jian‐He
Published: July 2015

Two robust stereocomplementary carbonyl reductases are identified through rescreening the carbonyl reductase toolbox.
ChemInform Abstract: Catalytic Asymmetric Crotylation of Aldehydes: Application in Total Synthesis of (‐)‐Elisabethadione.
Authors: O'Hora Paul S. , Incerti‐Pradillos Celia A. , Kabeshov Mikhail A. , Shipilovskikh Sergei A. , Rubtsov Aleksandr E. , Elsegood Mark R. J. , Malkov Andrei V.
Published: July 2015

The crotylation of aldehydes by trichlorocrotylsilane yields β‐methyl homoallylic alcohols with high enantioselectivity.
ChemInform Abstract: A Facile Synthesis of Vicinal cis‐Diols from Olefins Catalyzed by in situ Generated MnxOy Nanoaggregates.
Authors: Dalmizrak Digdem , Goeksu Haydar , Gueltekin Mehmet Serdar
Published: July 2015

Linear and cyclic alkenes are directly transformed to the corresponding vicinal cis‐diols by dihydroxylation with a KMnO4/H2O2 system.
ChemInform Abstract: Perfluorobutyl Iodide‐Assisted Direct Cyanomethylation of Azoles and Phenols with Acetonitrile.
Authors: Zhang Juan , Wu Wei , Ji Xinfei , Cao Song
Published: July 2015

The cyanomethylated products are smoothly obtained under mild reaction conditions without the use of a transition‐metal catalyst or other additional radical initiators.
ChemInform Abstract: Silver‐Mediated Oxidative Aliphatic C—H Trifluoromethylthiolation.
Authors: Guo Shuo , Zhang Xiaofei , Tang Pingping
Published: July 2015

A practical and direct trifluoromethylthiolation reaction of unactivated aliphatic C—H bonds is developed employing a silver‐based reagent.
ChemInform Abstract: Nickel‐Catalyzed Suzuki—Miyaura Coupling of a Tertiary Iodocyclopropane with Wide Boronic Acid Substrate Scope: Coupling Reaction Outcome Depends on Radical Species Stability.
Authors: Yotsuji Keisuke , Hoshiya Naoyuki , Kobayashi Takaaki , Fukuda Hayato , Abe Hiroshi , Arisawa Mitsuhiro , Shuto Satoshi
Published: July 2015

This is the first transition metal‐catalyzed Suzuki—Miyaura coupling reaction between a tertiary alkyl halide and a wide variety of aromatic boronic acids.
ChemInform Abstract: Diastereo‐ and Enantioselective Cyclopropanation of Alkyenyl Fluorides with Benzyl Diazoarylacetates.
Authors: Su Yan , Bai Miao , Qiao Jin‐Bao , Li Xiao‐Jing , Li Rui , Tu Yong‐Qiang , Gu Peiming
Published: July 2015

The cyclopropanation reaction is conducted in the presence of a chiral dirhodium catalyst and allows the synthesis of cis‐β‐fluorocyclopropane carboxylates with high diastereoselectivities and enantioselectivities.
ChemInform Abstract: Biosilica as an Efficient Heterogeneous Catalyst for ipso‐Hydroxylation of Arylboronic Acids.
Authors: Mahanta Abhijit , Adhikari Pooja , Bora Utpal , Thakur Ashim Jyoti
Published: July 2015

A green synthesis of phenols from areneboronates is presented by using aqueous H2O2 as an oxidant and biosilica as a catalyst.
ChemInform Abstract: Acylative Suzuki Coupling of Amides: Acyl‐Nitrogen Activation via Synergy of Independently Modifiable Activating Groups.
Authors: Li Xijing , Zou Gang
Published: July 2015

A new highly efficient palladium‐catalyzed acylative cross‐coupling of carboxylic amides with arylboronic acids features not only good functional group tolerance but also modifiable reactivities to overcome steric hindrance.
ChemInform Abstract: Conversion of α,β‐Unsaturated Ketones to 1,5‐Diones via Tandem Retro‐Aldol and Michael Addition Using Co(acac)2 Covalently Anchored onto Amine Functionalized Silica.
Authors: Sodhi Ravinderpal Kour , Paul Satya , Gupta Vivek K. , Kant Rajni
Published: July 2015

The method offers an interesting alternative to existing strategies based on homogeneous catalysis due to its easy work‐up and the recyclability of the catalyst which is reused in four consecutive cycles with slightly decreasing activity.
ChemInform Abstract: Facile and Efficient Synthesis of Hydroxyalkyl Esters from Cyclic Acetals Through Aerobic Photo‐Oxidation Using Anthraquinone‐2‐carboxylic Acid.
Authors: Yamaguchi Tomoaki , Kudo Yasuhisa , Hirashima Shin‐ichi , Yamaguchi Eiji , Tada Norihiro , Miura Tsuyoshi , Itoh Akichika
Published: July 2015

2‐Aryl and 2‐alkyl substituted 1,3‐dioxolanes and dioxanes are successfully transformed to the correspondingly substituted hydroxyethyl or hydroxypropyl esters, respectively.
ChemInform Abstract: Facile One‐Pot Transformation of Arenes into Aromatic Nitriles under Metal‐Cyanide‐Free Conditions.
Authors: Tamura Toshiyuki , Moriyama Katsuhiko , Togo Hideo
Published: July 2015

This method is also used in a four step synthesis of feboxostat (VIII) from compounds (V).
ChemInform Abstract: Iodine‐Catalyzed Ammoxidation of Methyl Arenes.
Authors: Guo Songjin , Wan Gen , Sun Song , Jiang Yan , Yu Jin‐Tao , Cheng Jiang
Published: July 2015

A new metal‐free direct ammoxidation of readily available methyl arenes leading to the corresponding nitriles is established under mild conditions.
ChemInform Abstract: Intramolecular Rearrangement of α‐Azidoperoxides: An Efficient Synthesis of tert‐Butyl Esters.
Authors: Pramanik Suman , Reddy Reddy Rajasekhar , Ghorai Prasanta
Published: July 2015

The required alkyl or aryl α‐azidoperoxide substrates may be prepared in situ starting from the corresponding aldehydes, thus offering a convenient one‐pot two‐step approach to tertiary alkylesters.
ChemInform Abstract: Metal‐Free Direct Construction of Sulfonamides via Iodine‐Mediated Coupling Reaction of Sodium Sulfinates and Amines at Room Temperature.
Authors: Wei Wei , Liu ChunLi , Yang Daoshan , Wen Jiangwei , You Jinmao , Wang Hua
Published: July 2015

The reaction fails for aliphatic sodium sulfinates (not shown).
ChemInform Abstract: Synthesis of Vinyl Trifluoromethyl Thioethers via Copper‐Mediated Trifluoromethylthiolation of Vinyl Bromides.
Authors: Huang Yangjie , Ding Jianping , Wu Chuyi , Zheng Huidong , Weng Zhiqiang
Published: July 2015

The reaction of various vinyl bromide substrates with copper complex (II) affords the desired thioethers with good to excellent yields.
ChemInform Abstract: Cobalt‐Catalyzed Intermolecular Oxidative Isocyanide Insertion with Two Amines: An Approach to Guanidines.
Authors: Zhu Tong‐Hao , Wang Shun‐Yi , Wei Tian‐Qi , Ji Shun‐Jun
Published: July 2015

If appropriate, products have been isolated as hydrochlorides after treatment with gaseous HCl in EtOAc.
ChemInform Abstract: N‐Heterocyclic Carbene Catalyzed Redox Isomerization of Esters to Functionalized Benzaldehydes.
Authors: Candish Lisa , Levens Alison , Lupton David W.
Published: July 2015

An NHC‐catalyzed conversion of trienyl esters such as (I) to benzaldehydes (II) via a cascade coupled with a rare redox isomerization is described.
ChemInform Abstract: Ligand‐Promoted Oxidative Cross‐Coupling of Aryl Boronic Acids and Aryl Silanes by Palladium Catalysis.
Authors: Yu Jingxun , Liu Jun , Shi Guangfa , Shao Changdong , Zhang Yanghui
Published: July 2015

Oxidative coupling of trialkoxyarylsilanes with areneboronates gives various biaryls.
ChemInform Abstract: Stereoselective Synthesis of Highly Functionalized Dispirooxindoles Through [3 + 2] Cycloaddition of Carbonyl Ylides with 3‐Arylideneoxindoles.
Authors: Reddy Basi V. Subba , Karthik Govindaraju , Rajasekaran Tamilselvan , Sridhar Balasubramanian
Published: July 2015

The three component reaction of α‐diazoamides, arylideneoxindoles, and aldehydes offers a novel synthesis of dispirooxindoles (IV) and (VII).
ChemInform Abstract: Asymmetric Synthesis of Spirocyclic Oxindole‐Fused Tetrahydrothiophenes via N,N′‐Dioxide‐Nickel(II) Catalyzed Domino Reaction of 1,4‐Dithiane‐2,5‐diol with 3‐Alkenyloxindoles.
Authors: Zhou Pengfei , Cai Yunfei , Lin Lili , Lian Xiangjin , Xia Yong , Liu Xiaohua , Feng Xiaoming
Published: July 2015

A domino thia‐Michael/aldol reaction is involved in the title synthesis.
ChemInform Abstract: Oxidative Amidation in the Naphthalene Series.
Authors: Jain Nikita , Ciufolini Marco A.
Published: July 2015

A facile method for the oxidative ortho‐cyclization of 1‐ and 2‐naphtholic sulfonamides as well as a new method for the preparation of N‐unsubstituted spirolactam derivative (X) of 1‐naphthol is given.
ChemInform Abstract: Organocatalytic Diels—Alder Reaction of 2‐Vinylindoles with Methyleneindolinones: An Efficient Approach to Functionalized Carbazolespirooxindoles.
Authors: Huang Lin‐Jie , Weng Jiang , Wang Sheng , Lu Gui
Published: July 2015

An unprecedented asymmetric Diels—Alder reaction is described.
ChemInform Abstract: Synthesis of 2‐Aryl and 3‐Aryl Benzo[b]furan Thioethers Using Aryl Sulfonyl Hydrazides as Sulfenylation Reagents.
Authors: Zhao Xia , Zhang Lipeng , Lu Xiaoyu , Li Tianjiao , Lu Kui
Published: July 2015

The biologically and pharmaceutically important scaffolds are readily available from substituted benzofurans under conditions A).
ChemInform Abstract: Asymmetric Hydroalkoxylation of Non‐activated Alkenes: Titanium‐Catalyzed Cycloisomerization of Allylphenols at High Temperatures.
Authors: Schlueter Johannes , Blazejak Max , Boeck Florian , Hintermann Lukas
Published: July 2015

A microwave‐assisted enantioselective intramolecular hydroxyalkylation of 2‐allylphenols at high temperatures yields 2‐methylcoumarans.
ChemInform Abstract: Synthesis of 2‐Alkylnaphtho[2,1‐b]furans via 2‐(1‐Formyl‐2‐naphthoxy)alkanoic Acids.
Authors: Wodnicka Alicja , Kwiecien Halina , Smist Malgorzata
Published: July 2015

A simple and efficient protocol for the synthesis of novel 2‐alkylnaphthofurans (V) (4 examples) via cyclization of appropriate 2‐(1‐formyl‐2‐naphthoxy)alkanoic acids, (IV) under Perkin reaction conditions is developed.
ChemInform Abstract: Highly Efficient Syntheses of α‐Amino Ketones and Pentasubstituted Pyrroles Using Reusable Heterogeneous Catalysts.
Authors: Farahi Mahnaz , Tamaddon Fatemeh , Karami Bahador , Pasdar Shahram
Published: July 2015

Silica supported wolframates and carbonates are successfully employed as catalysts for the two step synthesis of pyrroles via condensation of initially formed α‐aminoketones with alkyne (IV).
ChemInform Abstract: Synthesis of 2‐(3′‐Indolyl)tetrahydrofurans by Oxidative Cycloetherification.
Authors: Gillard Rachel M. , Sperry Jonathan
Published: July 2015

The desired heterocyclic system is readily available within a short time.
ChemInform Abstract: Metal‐Free N‐Arylation of Indolines with Diaryliodonium Salts.
Authors: Riedmueller Stefan , Nachtsheim Boris J.
Published: July 2015

N‐Arylindolines are obtained in up to 85% yield without use of any additional additives.
ChemInform Abstract: Metal‐Free Arylalkylation of N‐Aryl Acrylamides with Azobisalkylnitriles.
Authors: Tian Qingshan , He Ping , Kuang Chunxiang
Published: July 2015

An efficient and environmentally benign approach for the synthesis of cyano‐containing oxindoles with a quarternary carbon center is presented.
ChemInform Abstract: Iron‐Catalyzed Cross Dehydrogenative Coupling (CDC) of Indoles and Benzylic C—H Bonds.
Authors: Guo Shuaibo , Li Yaxuan , Wang Yu , Guo Xin , Meng Xu , Chen Baohua
Published: July 2015

Utilization of the N,N‐Dimethylcarbamoyl is crucial for successful coupling.
ChemInform Abstract: Palladium‐Catalyzed C‐7 Alkenylation of Indolines Using Molecular Oxygen as the Sole Oxidant.
Authors: Yang Dong , Mao Shuai , Gao Ya‐Ru , Guo Dong‐Dong , Guo Shi‐Huan , Li Bin , Wang Yong‐Qiang
Published: July 2015

All products (III), (V), (VII), and (VIII) are E‐isomers at the C‐7 position, and no Z‐isomers or other position substituted products can be detected.
ChemInform Abstract: Synthesis and Evaluation of Novel Oxoisoindoline Derivatives as Acetylcholinesterase Inhibitors.
Authors: Rayatzadeh Ayeh , Saeedi Mina , Mahdavi Mohammad , Rezaei Zahra , Sabourian Reyhaneh , Mosslemin Mohammad Hossein , Akbarzadeh Tahmineh , Foroumadi Alireza , Shafiee Abbas
Published: July 2015

The title compounds (IV), and (VI) are obtained by Ugi reaction of 2‐formylbenzoic acids, amines, and isocyanides.
ChemInform Abstract: Sonogashira Coupling and Garratt—Braverman Cyclization in Tandem: Formation of Four C—C Bonds Leading to the Synthesis of Aryl Dihydro Isofurans and Isoindoles.
Authors: Ghosh Debaki , Pal Paramita , Basak Amit
Published: July 2015

Bispropargyl ether or N‐bispropargyl sulfonamide and various aryl bromides or aryl iodides equipped with electronically and sterically diverse substituents are successfully transformed to the corresponding symmetrically aryl‐substituted bispropargyl derivatives.
ChemInform Abstract: Benzimidazoles and Benzoxazoles via the Nucleophilic Addition of Anilines to Nitroalkanes.
Authors: Aksenov Alexander V. , Smirnov Alexander N. , Aksenov Nicolai A. , Bijieva Asiyat S. , Aksenova Inna V. , Rubin Michael
Published: July 2015

The reaction of phenylenediamines and 2‐aminophenols (I) with nitroalkanes (II) in PPA leads to desired benzimidazoles and benzoxazoles (III) in high yields, whilst the reaction with 2‐nitro‐1‐phenylethan‐1‐one (IV) affords unexpected 2‐phenyl substituted products.
ChemInform Abstract: Boron‐Catalyzed Arylthiooxygenation of N‐Allylamides: Synthesis of (Arylsulfanyl)oxazolines.
Authors: Yu Jipan , Tian Hua , Gao Chang , Yang Haijun , Jiang Yuyang , Fu Hua
Published: July 2015

The title compounds are efficiently and simply obtained using readily available 1‐(arylsulfanyl)pyrrolidine‐2,5‐diones as arylsulfanylating reagents and inexpensive boron trifluoride etherate as catalyst.
ChemInform Abstract: 4‐Trimethylsilyl‐5‐iodo‐1,2,3‐triazole: A Key Precursor for the Divergent Syntheses of 1,5‐Disubstituted 1,2,3‐Triazoles.
Authors: Li Lingjun , Shang Tongpeng , Ma Xiaonan , Guo Haiyun , Zhu Anlian , Zhang Guisheng
Published: July 2015

A wide range of 1,5‐disubstituted 1,2,3‐triazoles are obtained via sequential copper/palladium‐catalyzed coupling and desilylation reactions of readily available title compounds (III) in one‐pot.
ChemInform Abstract: Copper on Chitosan: An Efficient and Easily Recoverable Heterogeneous Catalyst for One Pot Synthesis of 1,2,3‐Triazoles from Aryl Boronic Acids in Water at Room Temperature.
Authors: Anil Kumar B. S. P. , Reddy K. Harsha Vardhan , Karnakar K. , Satish G. , Nageswar Y. V. D.
Published: July 2015

The efficient environmentally benign protocol provides 1,4‐disubstituted 1,2,3‐triazoles regioselectively and in high yields.
ChemInform Abstract: Gold(I)‐Catalyzed Asymmetric Desymmetrization of meso‐Alkynyl Diols and Kinetic Resolution of the Corresponding‐Diols: Effects of Celite Filtration and Silver Salts.
Authors: Sota Yumi , Yamamoto Masaaki , Murai Masato , Uenishi Jun'ichi , Uemura Motokazu
Published: July 2015

A combination of a chiral diphosphine precatalyst and a silver salt co‐catalyst allows the cyclization of meso‐alkynyl diols (I) and (V) to optically active isochromenes.
ChemInform Abstract: A Domino Synthetic Approach for New, Angular Pyrazol‐ and Isoxazol‐Heterocycles Using [DBU][Ac] as an Effective Reaction Medium.
Authors: Sutariya Tushar R. , Labana Balvantsingh M. , Parmar Bhagyashri D. , Parmar Narsidas J. , Kant Rajni , Gupta Vivek K.
Published: July 2015

Synthesis of new pyrazol‐ and isoxazol‐based heterocycles via reaction of O‐alkenylated acetophenones as typical and rarely studied domino/Knoevenagel‐hetero‐Diels—Alder substrates with active methylene‐pyrazolone and ‐isoxazolone, resp., is described.
ChemInform Abstract: EGFR/HER‐2 Inhibitors: Synthesis, Biological Evaluation and 3D‐QSAR Analysis of Dihydropyridine‐Containing Thiazolinone Derivatives.
Authors: Ren Yu‐Jia , Wang Zhong‐Chang , Zhang Xin , Qiu Han‐Yue , Wang Peng‐Fei , Gong Hai‐Bin , Jiang Ai‐Qin , Zhu Hai‐Liang
Published: July 2015

Compound (IIIe) is found to exhibit high antiproliferative activity against B16‐F10, HeLa, and MCF‐7 in vitro.
ChemInform Abstract: Ultrasound Assisted Multicomponent Reactions: A Green Method for the Synthesis of Highly Functionalized Selenopyridines Using Reusable Polyethylene Glycol as Reaction Medium.
Authors: Khan Md. Nasim , Karamthulla Shaik , Choudhury Lokman H. , Haque Faizi Md. Serajul
Published: July 2015

2‐Amino selenopyridine derivatives (IV) are simply obtained by one‐pot, three‐component reaction of various aldehydes (I), malononitrile (II), and benzeneselenol (III) using ultrasound.
ChemInform Abstract: Redox Cycloisomerization Approach to 1,2‐Dihydropyridines.
Authors: Trost Barry M. , Biannic Berenger
Published: July 2015

Starting from protected propargyl imines an efficient one‐pot approach to 1,2‐dihydropyridines is elaborated.
ChemInform Abstract: Convenient Synthesis of Novel Heteroatom‐Substituted Quinolines via Friedlaender Annulation Using Phosphotungstic Acid as a Reusable Catalyst.
Authors: Chen Meng‐Meng , Zhang Min , Xie Feng , Wang Xiao‐Ting
Published: July 2015

The title compounds (III), (V), (VII), (IX), and (XI) are efficiently obtained from 2‐aminoaryl ketones and α‐heteroatom bearing ketones under solvent‐free reaction conditions.
ChemInform Abstract: An Efficient Synthesis of 1,3‐Disubstituted 5‐Diethoxyphosphoryluracils.
Authors: Pieta Marlena , Kedzia Jacek , Janecki Tomasz
Published: July 2015

Sequential reaction of diethylphosphoryl acetamides with acetal (II), and amines followed by cyclization in the presence of phosgene affords the title compounds in good yields.
ChemInform Abstract: An Eco‐Friendly Pictet—Spengler Approach to Pyrrolo‐ and Indolo[1,2‐a]quinoxalines Using p‐Dodecylbenzenesulfonic Acid as an Efficient Broensted Acid Catalyst.
Authors: Preetam Amreeta , Nath Mahendra
Published: July 2015

An efficient, facile, and environmentally friendly method for the synthesis of various pyrrolo[1,2‐a]quinoxaline, dihydropyrrolo[1,2‐a]quinoxaline, and spiro[indoline‐3,4′‐pyrrolo[1,2‐a]quinoxalin]‐2‐one derivatives under mild reaction conditions is developed.
ChemInform Abstract: Stereoselective Formation of Eight‐Membered Rings by Radical Cyclization of Silylenedioxy‐Tethered Bis‐methacrylate Derivatives.
Authors: Meng Fan‐Yi , Huang Shou‐Ling , Liu Yi‐Hung , Hu Ziqiang , Lai Guoqiao , Luh Tien‐Yau
Published: July 2015

Treatment of diester substrate (I) with halogen reactants (II) under conditions A), i.e.
ChemInform Abstract: Tirucallane‐Type Triterpenoids from the Fruit of Ficus carica and Their Cytotoxic Activity.
Authors: Jing Lin , Zhang Yang‐Mei , Luo Jian‐Guang , Kong Ling‐Yi
Published: July 2015

Nine new tirucallane‐type triterpenoids, ficutirucins A—I, are isolated and evaluated for their cytotoxicity.
ChemInform Abstract: Three New Bisabolane Sesquiterpenes from Ligularia songarica.
Authors: Dai Wei , Xie Zhou‐Jian , Li Mei , Wang Qi
Published: July 2015

Three new bisabolane sesquiterpenes, songaricalarins F—H, are isolated along with five know analogues.
ChemInform Abstract: Synthetic Efforts Toward the Lycopodium Alkaloids Inspires a Hydrogen Iodide Mediated Method for the Hydroamination and Hydroetherification of Olefins.
Authors: Leger Paul R. , Murphy Rebecca A. , Pushkarskaya Eugenia , Sarpong Richmond
Published: July 2015

The synthesis of the tricyclus (VI), which is a useful precursor for the preparation of Lycopodium alkaloids involves a Diels—Alder cycloaddition and the cyclization of amine (V) as the key steps.
ChemInform Abstract: Bioactive Diphenyl Ether Derivatives from a Gorgonian‐Derived Fungus Talaromyces sp.
Authors: Chen Min , Han Lei , Shao Chang‐Lun , She Zhi‐Gang , Wang Chang‐Yun
Published: July 2015

Three new diphenyl ether derivatives, talaromycins A—C, are isolated together with six known analogues and evaluated for their cytotoxic and antifouling activities.
ChemInform Abstract: Photocurrent Generation with Two‐Dimensional van der Waals Semiconductors
Authors: Buscema Michele , Island Joshua O. , Groenendijk Dirk J. , Blanter Sofya I. , Steele Gary A. , van der Zant Herre S. J. , Castellanos‐Gomez Andres
Published: July 2015

Review: 221 refs.
ChemInform Abstract: Chemically Controllable Fabrication of One‐Dimensional ZnO Nanostructures and Their Applications in Solar Cells
Authors: Zhang Yuqi , Heng Liping , Jiang Lei
Published: July 2015

Review: 171 refs.
ChemInform Abstract: 1,1‐Dilithiosilanes, 1,1‐Dilithiogermanes, 1,1‐Dilithiostannanes and Related Compounds: Organometallic Reagents of the new Generation
Authors: Lee Vladimir Ya. , Sekiguchi Akira
Published: July 2015

Review: [48 refs.
ChemInform Abstract: Efficient Gold(I) Catalyzed Asymmetric Hydroamination of Alkenes
Authors: Abadie Marc‐Antoine , Medina Lorian , Agbossou‐Niedercorn Francine , Michon Christophe
Published: July 2015

Review: 36 refs.
ChemInform Abstract: Quadruple‐Decker Phthalocyanines — One Additional Layer for a Molecule, One Giant Leap for Phthalocyanine Chemistry
Authors: Fukuda Takamitsu , Ishikawa Naoto
Published: July 2015

Review: 58 refs.
ChemInform Abstract: Fate of Diclofenac in Municipal Wastewater Treatment Plant — A Review
Authors: Vieno Niina , Sillanpaa Mika
Published: July 2015

Review: 113 refs.
ChemInform Abstract: Highlights on the Synthesis and Biological Activity of 1,3‐Selenazoles
Authors: Facchinetti Victor , Nery Ana C. S. , Avellar Marcela M. , Gomes Claudia R. B. , de Souza Marcus V. N. , Vasconcelos Thatyana R. A.
Published: July 2015

Review: 59 refs.
ChemInform Abstract: Synthesis of β‐Lactams and Their Reactivity
Authors: El‐Kanzi N. A. A.
Published: July 2015

Review: 144 refs.
ChemInform Abstract: When Cross‐Coupling Partners Meet Indolylphosphines
Authors: Wong Shun Man , Yuen On Ying , Choy Pui Ying , Kwong Fuk Yee
Published: July 2015

Review: 192 refs.
ChemInform Abstract: New Developments in Direct Functionalization of C—H and N—H Bonds of Purine Bases via Metal Catalyzed Cross‐Coupling Reactions
Authors: Abdoli Morteza , Mirjafary Zohreh , Saeidian Hamid , Kakanejadifard Ali
Published: July 2015

Review: [66 refs.
ChemInform Abstract: Recent Developments in the Trifluoromethylation of Alkynes
Authors: Gao Pin , Song Xian‐Rong , Liu Xue‐Yuan , Liang Yong‐Min
Published: July 2015

Review: 49 refs.
ChemInform Abstract: Versatile Electrochemical C—H Amination via Zincke Intermediates
Authors: Waldvogel Siegfried R. , Moehle Sabine
Published: July 2015

Review: 29 refs.