bluuebunny/crossref_metadata_2025 huggingface dataset:
Advanced Engineering Schools: Transfer of Competencies and Innovations in the Interests of Regional and Sectoral Development
Authors: Keller A. V. , Suvorov A. V. , Shadrin S. S. , Korshunov I. A. , Shirkova N. N.
Published: February 2025

The creation of advanced engineering schools at universities to improve the quality of human capital is becoming increasingly relevant. This paper examines the relationship between the development of economics, engineering education, the results of intellectual activity and the scale of launching new educational programs in universities.

The analysis demonstrates that activities in the field of engineering education will develop in the interests of knowledge transfer in areas of technological sovereignty with large amounts of investment. However, so far, the educational activity of advanced engineering schools correlates with the level of development of industries in the regions, which creates challenges and opportunities for expanding cooperation and introducing technologies beyond their borders throughout the industry.

The study shows that the scale of launching new educational programs is interconnected with the general culture of research and the creation of professional education programs at the university. The high potential of research activities, in general, is a prerequisite for the development and implementation of engineering educational programs in demand in the real sector. At the same time, the results of scientific and intellectual activity are often the source of their creation. The high level of launching additional professional education programs at the university makes it possible to expand the involvement of university teams in the development and implementation of educational programs and engineering orientation.

The authors offer practical recommendations aimed at further development of engineering education for both students in educational institutions and current specialists in the interests of ensuring the technological sovereignty of the Russian Federation, the development of the university’s third mission, as well as to stimulate sales of educational programs, innovative solutions and projects.
Influence of irradiation on release of endothelial microparticles (EMP) in vitro
Authors: Neuber Christin , Pufe Johanna , Pietzsch Jens
Published: February 2025

Survivors of Hodgkin’s disease as well as of breast and lung cancer are at risk of radiation-associated cardiovascular disease. Recent studies demonstrated a correlation between cardiovascular risk factors and circulating endothelial microparticles (EMP) and thereby suggest increased EMP levels in circulation to be an early biomarker of endothelial dysfunction and cardiovascular risk. This prompted us to analyze the amount of EMP released by human aortic endothelial cells (HAEC) after exposure to different doses of X-ray (0.4, 2, 4, 6, and 20 Gy) using antibodies against the endothelial cell markers CD31, CD144, and CD146 by flow cytometry. In this pilot experiment only CD146 proved appropriate for quantification of HAEC-derived EMP. Exposure of HAEC to different doses of X-ray did not significantly influence formation of CD146-positive EMP. However, low doses (0.4 Gy) tended to decrease EMP formation, whereas higher doses (2 or 4 Gy) slightly increased release of CD146-positive EMP. By contrast, inflammatory activation of HAEC by TPA significantly increased EMP release about 15-fold ( P <  0.01). In conclusion, under the present experimental conditions EMP did not prove a suitable biomarker for radiation-induced endothelial dysfunction in vitro.
Peripherisiert, marginalisiert, einverleibt
Authors: Boemke Laura , Haubner Tine , Laufenberg Mike
Published: February 2025

In unserer Forschung zu ländlichen Peripherien setzten wir uns mit dem marxistischen Konzept der Surplusbevölkerung auseinander, um damit ein charakteristisches Element von Prozessen der Klassenbildung in den »inneren Peripherien« Ost- und Westdeutschlands zu erfassen. Als Surplusifizierung theoretisieren wir den dynamischen und räumlich kontingenten Prozess der Herstellung vermeintlich überflüssiger Bevölkerungsgruppen. Auf der Basis empirischer Forschung und eines erweiterten Begriffs von Arbeit werden drei Dimensionen dieser aktiven Produktion und Verwaltung von Surplusbevölkerungen – Peripherisierung, Marginalisierung und Einverleibung – in ihrem Zusammenhang ausgelotet.
Occupational pesticide exposure and cognitive impairment among adult farmers in northern Thailand
Authors: Phitsadang Nichapa , Naksen Warangkana , Ong-Artborirak Parichat
Published: February 2025

Background

Thai farmers are directly exposed to pesticides, which may result in adverse effects including cognitive impairment.

Objective

The aim of this study was to examine the association between occupational pesticide exposure and cognitive decline among adult farmers in northern Thailand.

Material and Methods

This cross-sectional study included 303 pesticide-using farmers over the age of 50 from Doi Tao District in Chiang Mai Province. Pesticide exposure score was calculated using an algorithm that considered personal protective equipment (PPE) scores and exposure intensity scores, as well as lifetime application days. The scores were classified as high or low exposure based on their median. The Thai version of the Montreal Cognitive Assessment (MoCA)
test was used to assess cognitive function.

Results

The mean age of adult farmers was 58.74 years. The prevalence of cognitive impairment was 93.7%, with an average score of 19.6. Spearman’s rank correlation coefficient showed that the MoCA score was adversely correlated with lifetime application days (rs = -0.145), PPE score (rs = -0.163), exposure intensity score (rs = -0.184), and pesticide exposure score (rs = -0.225). Linear regression revealed that high exposed farmers had significantly lower MoCA scores than low exposed farmers, as measured by PPE score (B = -0.75; 95% CI: -1.46, -0.05), exposure intensity score
(B = -0.97; 95% CI: -1.66, -0.27), and pesticide exposure score (B = -0.77; 95% CI: -1.47, -0.06), after controlling for sex, age, education, income sufficiency, and body mass index.

Conclusions

Thai farmers are at risk of cognitive impairment linked to occupational pesticide exposure, depending on their PPE use and exposure intensity. There is still a critical need for action to reduce the risk of negative health effects from pesticide exposure among Thai farmers.
La paradoja del plástico en la salud: herramienta vital, contaminante letal
Authors: Olive Castillo Fernanda , Giglio Andrés , Ferre Andrés , Sanhueza María Bernardita
Published: February 2025

El uso de plásticos en la atención de salud plantea una paradoja crítica, mientras facilita la atención médica, pero su eliminación inadecuada amenaza la salud humana y planetaria. Existe un impacto ambiental en el sector salud, destacando que hasta el 83% de los residuos hospitalarios a nivel global pueden ser plásticos, con efectos nocivos para la salud, como cáncer, afecciones cardiovasculares y enfermedades respiratorias. En Chile, solo el 2% de los residuos hospitalarios se reciclan, mientras que el 98% se dispone en vertederos. La presencia de microplásticos en fluidos y tejidos humanos, como sangre y bulbo olfatorio, expone la gravedad del problema. La exposición prolongada se asocia con patologías oncológicas, cardiovasculares y respiratorias, comprometiendo el principio ético de “no hacer daño”. Por lo anterior, existe la necesidad de integrar estrategias sostenibles en la gestión de residuos hospitalarios, con la implementación de equipos “Green Teams” para reducir el uso de insumos desechables, reutilizar materiales y fomentar el reciclaje. En Chile, la adhesión de 233 instituciones de salud a la Red Global de Hospitales Verdes y Saludables marca un avance, pero persisten desafíos en la educación ambiental de los profesionales de la salud y la implementación de políticas efectivas. En este contexto, enfermería se posiciona como actor clave para liderar este cambio, dada su capacidad de intervención directa en la atención clínica, la formación académica y la gestión de residuos. La sostenibilidad debe ser un eje central en la transformación del sector salud, proponiendo la educación ambiental en mallas curriculares y el fortalecimiento de la investigación local para la formulación de políticas públicas. Este enfoque asegura el equilibrio entre la atención de calidad a los pacientes y la protección del planeta, garantizando un futuro más saludable para todos.
Efek Jangka Pendek Meditasi Anapanasati
Authors: Astuti Dewi , Yati Ida , Surya Julia
Published: February 2025

Penelitian ini bertujuan untuk mengevaluasi dampak meditasi Samatha Bhavana, khususnya dengan menggunakan Anapanasati sebagai objek, terhadap tingkat konsentrasi peserta selama periode tujuh hari. Penelitian dilakukan di Vihara Dharma Subha dengan melibatkan 40 subjek yang menjalani penilaian konsentrasi sebelum dan sesudah meditasi. Data dikumpulkan menggunakan tes kognitif. Analisis statistik deskriptif dan inferensial, termasuk uji t-pasangan, digunakan untuk mengevaluasi perubahan tingkat konsentrasi. Hasil penelitian menunjukkan peningkatan signifikan dalam skor konsentrasi peserta setelah retret meditasi (rata-rata skor meningkat dari 65,4 menjadi 78,6; p < 0,01). Temuan ini konsisten dengan penelitian sebelumnya yang menunjukkan bahwa meditasi dapat meningkatkan fungsi kognitif, termasuk perhatian, memori, dan kontrol eksekutif. Penelitian ini memberikan bukti bahwa meditasi Anapanasati dapat menjadi alat yang efektif untuk meningkatkan konsentrasi dan kesehatan mental dalam jangka pendek. Implikasi penelitian ini mencakup pengembangan program meditasi dalam berbagai konteks, termasuk pendidikan dan perawatan kesehatan mental
Model of formation of graduates’ knowledge and skills on the example of the educational program “Applied Informatics”
Authors: Golchevskiy Yu. V. , Babenko V. V.
Published: February 2025

The current implementation status of basic professional education programs (BPEP) in universities is characterized by a number of problems: for example, BPEPs are not fast enough to take into account changes in the labor market requirements to the target professional capabilities of graduates. In addition, there are not enough mechanisms in BPEP that allow monitoring and operational control over the effectiveness of training and compliance of the competencies of the academic component with the labor functions set out in professional standards. The article proposes an approach to modeling and formalization of BPEP based on the concept of skills development.

Different approaches to the development of educational programs are analyzed, their formalization and visualization is carried out on the basis of the method presented by the authors on the example of 09.03.03 “Applied Informatics” (the formats of mental maps, graphic metaphor “subway map”, etc. are used). The sequence of BPEP design is considered, the importance of the analysis of the program development strategy is noted.

The use of the described model makes it possible to offer new solutions to improve the effectiveness of professional educational programs, to ensure their practice orientation and flexibility, but most importantly, it makes it possible to achieve the demand for graduates in the labor market due to the reliance on the exact correspondence of skills mastered by graduates in the university to the requirements of employers.
Intelligent adaptive learning system based on neural networks for personalization of educational trajectories of Russian university students
Authors: Podkolzin M. M.
Published: February 2025

One of the ways to improve the quality and efficiency of higher education in Russia is to personalize learning, to find ways to create an individual educational trajectory for each student. Traditional teaching methods do not consider the individual characteristics of students, while the development of digital technologies, including artificial intelligence technologies, creates new ways to transform the higher education system.

The article presents a tool for personalizing the educational trajectories of students in Russian universities — an intelligent adaptive learning system based on neural networks. During the research described in the article, the optimal neural network architecture was determined (using multilayer perсeptron, convolutional and recurrent neural networks). The created adaptive system was integrated into the infrastructure of five Russian universities, where an experiment on its application involving 1000 students was conducted. Then, the impact of the intelligent adaptive learning system on students’ academic performance and engagement as well as on teaching efficiency was evaluated. The evaluation methods were statistical analysis using Student’s t-test and analysis of variance, student and faculty surveys.

The results of the experimental application of the intelligent adaptive learning system demonstrate an accuracy of predicting the performance of the educational process up to 92 %, an increase the academic performance of students in the experimental group by 18 %, an increase of their involvement in the learning process by 25 %, as well as an increase in the efficiency of teachers’ work by 15 % with a decrease in time costs by 20 %.

The research presented in this article demonstrates a significant potential of intelligent adaptive learning systems to improve the quality of higher education in Russia. The results can be used for optimization of educational programs and teaching methods. Further research is needed on the long-term impact of the presented adaptive learning system on the career trajectories of graduates and the labor market demand for the graduates.
Using large language models to develop skills in analyzing media context in students of philological specialties
Authors: Yiwen G.
Published: February 2025

Under modern conditions of digitalization of education, including liberal arts education, the use of natural language processing technologies and large language models (LLM) is of particular relevance and practical significance for improving professional training of students of philological specialties. The article explores the possibilities of using LLM for objective analysis of media context in the training of philology students. On the basis of critical analysis of literature and empirical research using the methods of thematic modeling, tonality analysis and fact extraction on the material of a corpus of 5,2 million media texts, the key thematic and linguistic features of the media context significant for the development of professional competencies of philology students are revealed. A conceptual model of integrating LLM methods into adaptive learning systems for personalized formation of media context analysis skills was developed. Experimental testing of the model on a sample of 120 students demonstrated a statistically significant increase in learning outcomes and learner satisfaction compared to the control group. The obtained results open prospects for the creation of intelligent adaptive systems for training philologists to work in a transforming media landscape.
Optimizing Data Processing Through Edge-Cloud Integration: A Comprehensive Framework
Authors: Pruthvi Tatikonda
Published: February 2025

This article presents a comprehensive analysis of hybrid edge-cloud architectures in modern distributed computing systems, focusing on the synergistic integration of edge and cloud computing paradigms. The study examines the fundamental principles, implementation strategies, and challenges in creating efficient hybrid processing environments. Through detailed analysis of real-world case studies across autonomous vehicles, maritime operations, and healthcare sectors, we demonstrate the practical applications and benefits of hybrid processing approaches. The research encompasses technical specifications of algorithms, protocols, and frameworks essential for implementing robust hybrid systems. The investigation reveals both the current limitations of hybrid architectures and potential solutions through emerging technologies. The article proposes strategies for addressing these challenges through advanced connectivity solutions, AI-driven optimization, enhanced security frameworks, and architectural innovations. This article contributes to the growing body of knowledge in distributed computing by offering a structured approach to implementing and optimizing hybrid edge-cloud processing solutions while considering future technological advancements.
Cloud Transformation Success Stories: Navigating Complex Implementation Challenges
Authors: Mohit Sachdeva
Published: February 2025

This technical article examines landmark cases of successful cloud transformation initiatives across diverse industries, focusing on organizations that have effectively navigated complex implementation challenges. It presents detailed examinations of Netflix's massive-scale architecture transformation, Capital One's secure financial services migration, General Electric's industrial IoT platform implementation, and Volkswagen's legacy system modernization. Through these case studies, the article identifies critical success factors and common challenges in cloud adoption, including security and compliance requirements, integration complexities, and performance optimization strategies. It reveals how these organizations leveraged various cloud technologies and methodologies to achieve their transformation objectives while maintaining operational continuity. The article particularly emphasizes the importance of comprehensive security frameworks, robust architecture design, and effective change management strategies in successful cloud implementations. Furthermore, it provides insights into how organizations can effectively manage the transition from legacy systems to modern cloud infrastructure while ensuring business continuity and regulatory compliance.
Density Estimation for Financial Fraud Detection: A Multivariate Kernel-Based Approach
Authors: Basavaraj Talawar  , A. S. Talawar
Published: February 2025

The detection of insider trading has become increasingly challenging due to the complexity of modern financial markets. This paper introduces a novel approach using Volume-Weighted Multivariate Kernel Density Estimation to identify potential insider trading activities. By integrating volume-weighting with the Kernel Density Estimation framework, this method effectively captures abnormal price-volume relationships, providing a sophisticated means to flag irregular trading behaviour. This paper proposes a robust approach using Volume-Weighted Multivariate Kernel Density Estimation to detect abnormal trading patterns linked to insider trading and this approach improves traditional Kernel Density Estimation by incorporating trading volume as a weighting factor, allowing it to capture the joint distribution of stock returns and trading volumes. The model’s application is tested on data from companies targeted by Hindenburg Research, including Nikola Corporation, Clover Health, and Adani Enterprises. The results show clear pre-event anomalies, including increased trading volumes and price movements preceding the report releases. By utilizing adaptive bandwidth selection, Volume-Weighted Multivariate Kernel Density Estimation balances bias and variance to refine detection of insider trading activities in both dense and sparse regions of the data. The emergence of reports from activist short-sellers like Hindenburg Research has triggered significant market reactions, often accompanied by allegations of insider trading. This methodology is highly sensitive to abnormal volumes that may signal preemptive insider trading ahead of major market events, such as the release of damaging reports. This research demonstrates that VW-MKDE offers enhanced sensitivity to volume-weighted deviations, enabling the detection of abnormal trading behavior associated with potential insider information. Our findings highlight the tool’s capacity to assist regulators and analysts in identifying suspicious market activities in real-time, particularly during periods of heightened market volatility and post-report market responses.
GeoGebra en la resolución de problemas de cálculo en el área de Matemática
Authors: Guanochanga Llerena Katty Soraya , Casaliglla Ger Darwin Fabricio
Published: February 2025

The research addressed the teaching and learning of mathematics in primary education, with a particular focus on problem-solving, identified as a difficulty for students. The objective was to propose the use of GeoGebra as a didactic resource to address this difficulty in fourth-grade students of Basic General Education at the Bolívar Educational Unit in Tulcán. The methodology included a mixed approach of quasi-experimental design of the pre-experimental type, with a pretest-posttest design in three groups, without a control group. Interviews with teachers and surveys of students were conducted to understand their perspectives and prior skills with GeoGebra. Pretests and posttest were carried out, the first in conventional classes and the second, using GeoGebra; problem-solving was evaluated based on specific phases and metrics. Normality tests, one-way ANOVA, and N-Gain were calculated to determine the difference between groups. The results indicated that teachers see the need to use GeoGebra and that students have difficulties in problem-solving due to reasoning problems. Students expressed not having used GeoGebra, but showed interest in its use. The data were parametric, and there were no significant differences between groups. However, an improvement was observed between pretest and posttest scores, although no significant differences were found between phases and scores. In conclusion, the use of GeoGebra is shown as a positive resource for learning mathematics.
Kahoot para la enseñanza del idioma inglés
Authors: Puetate Medina Edwin Emilio , Castillo Martínez Cristhian Patricio , Méndez Ortega Maritza Genoveva
Published: February 2025

The usual methods of teaching English have limitations, which are exacerbated by the lack of digital skills in both teachers and students, leading to poor performance in this subject across Ecuador. Therefore, the objective was to implement Kahoot in the English teaching-learning process with 331 students from the Unified General Baccalaureate of the Fiscomisional Educational Unit Hermano Miguel La Salle in Tulcán to improve their English language skills. We used a mixed and causal approach, combining field and documentary methods with a pre-experimental quasi-experimental design that included pre- and post-tests. The methodology consisted of interviewing 7 teachers and conducting surveys on Microsoft Forms and Kahoot with students to assess their English skills. We applied Kolmogorov-Smirnov as a normality test, and the results indicated that the question response distributions were not normal. Given this, we used the non-parametric Wilcoxon test to compare the pretest and posttest scores, as the number of samples exceeded 30. In conclusion, the use of Kahoot had a positive and significant impact on motivation for active participation and accessibility in learning English, as well as on competitiveness in learning English through games, but it highlights the need to train teachers to optimize its use and effectiveness in the classroom
Biota asociada al guano de murciélagos en cuevas cuarzoareníticas de la Amazonia colombiana
Authors: Muñoz-Saba Yaneth , Neita-Moreno Jhon Cesar , Perdomo-Gaitán María Alejandra , Gómez-Hernández Juan , Sauro Francesco , Lasso Carlos A.
Published: February 2025

Se presenta la biota de invertebrados asociada a diferentes tipos de guano recolectado en las cuevas cuarzoareníticas de Los Guácharos y Necaeridagoda ubicadas en la Serranía de Chiribiquete, departamento del Caquetá, Amazonía colombiana. Se realizó una caracterización de las cavidades haciendo énfasis en la ubicación del guano recolectado y se llevó a cabo un tamizaje selectivo en el laboratorio para diferenciar la mayor cantidad de morfos. Se analizaron 457 especímenes que representan dos filos, siendo Arthropoda el mejor representado. Dentro de este, la clase Insecta alcanzó el 81,62 %. La riqueza trófica de la fauna está dominada por los detritívoros (78,95 %) y con registro de morfos troglobios (Fanniidae, Staphylinidae, Termitidae). Se hizo énfasis en la estandarización de la metodología, tanto en el campo como en el laboratorio.
Informing the Development of an English for IT Program: A Study on Student Perceptions and Language Skill Usage
Authors: Latifa Ammang , Nur Rafi'ah , Marlina
Published: February 2025

English proficiency is crucial for Information Technology (IT) students as it plays a vital role in their academic and professional success. This study aims to analyze IT students’ perceptions of their English language skills, focusing on their self-assessed mastery levels, frequency of use, and perceived importance of listening, speaking, reading, and writing skills. The findings are intended to inform the development of an English for Specific Purposes (ESP) curriculum tailored to the linguistic demands of the IT field. A quantitative research design was employed, utilizing a survey method to collect data from IT students at Universitas Muhammadiyah Parepare. The data were gathered through a structured questionnaire distributed via Google Forms, encompassing Likert-scale items to measure students’ perceptions of their English proficiency. Descriptive statistical analysis was conducted to examine the frequency of language skill usage, self-assessed mastery levels, and the perceived importance of each skill in academic and professional contexts. The results reveal that IT students frequently use their listening and reading skills for engaging with multimedia content and academic materials, whereas speaking and writing skills are primarily used in informal settings such as daily conversations and social media. However, students report lower confidence in performing formal communication tasks, such as delivering presentations and writing business correspondence. Despite recognizing the importance of all four language skills, students perceive listening and reading as more critical for their academic performance, while speaking and writing are viewed as essential for career advancement. These findings highlight the need for an ESP curriculum that bridges the gap between academic preparation and professional language demands by integrating industry-relevant content and practice-oriented instructional strategies. The study concludes that enhancing IT students' English proficiency requires targeted interventions that emphasize professional communication skills and real-world applications. The findings provide valuable insights for curriculum developers and educators in designing effective ESP programs that align with the evolving needs of IT students. Future research should explore the integration of technology-enhanced learning approaches and industry collaborations to further refine ESP instruction.
Reclaiming Indigeneity: A Postcolonial Analysis of Emile Habibi’s The Pessoptimist in Translation
Authors: Ben Khalifa Faical
Published: February 2025

This study investigates the linguistic and cultural markers of indigeneity in Emile Habibi’s The Secret Life of Saeed: The Pessoptimist, a novel translated into more than 12 languages and gaining worldwide recognition. In spite of this recognition, the translation of this indigenous chef-d’oeuvre does not seem to mirror its deep-seated connection to its linguistic and cultural origin. The study, therefore, highlights a gap in the literature that Jayyusi and Le Gassick's English translation of The Pessoptimist has not been verified for its preservation or dilution of the original’s essence of indigeneity. This study utilizes a qualitative textual analysis methodology premised on postcolonial translation studies to examine the novel’s linguistic and cultural indigenous markers. It then looks into the translation of those markers, only to realize that the indigenous novel has been metamorphosed into a mere narrative overshadowed by the dominant culture. This deformation has not only diluted the novel’s indigenous essence but also created gaps in understanding the work’s cultural specificity and identity. By highlighting specific instances of such distortions, the study emphasizes the amount of loss incurred in such conventional translation practices. By presenting critical insights into the challenges facing the translation of indigenous literature, this study not only contributes to the broader field of translation studies but also calls for a retranslation of The Pessoptimist, one that aligns with its true indigenous origin.
Perceptions of Nigerian Tax Officers and Stakeholders on the Adoption of Artificial Intelligence in Tax Risk Management.
Authors: Aina Adeola Temitope
Published: February 2025

The Nigerian tax system faces substantial hurdles, including tax evasion, avoidance, and non-compliance, resulting in significant revenue losses. To combat these problems, this study examines the potential of adopting artificial intelligence (AI) in Nigerian tax risk management, centered on its ability to improve tax compliance, minimize risk, and enhance revenue collection. A quantitative approach was used, and survey research was compiled on the perceptions of tax officers, taxpayers, and tax consultants on the proposed adoption of AI in the tax industry. The results reveal that tax officers are generally confident in using AI-driven tax risk management tools, perceiving them as improving audit accuracy and increasing audit efficiency. However, concerns regarding adequate training and support were raised. Taxpayers demonstrated moderate awareness of AI-driven tax risk management, with mixed perceptions about its impact on tax compliance, privacy, transparency, and trust. Consultants were optimistic about AI-driven tax risk management's effectiveness, impact, and enhancement of the overall tax system but highlighted concerns about resource adequacy and training needs. The study's findings provide valuable insights into the perceptions of Nigerian tax officers, taxpayers, and tax consultants on adopting AI in tax risk management, contributing to developing effective strategies for improving tax compliance and revenue collection in Nigeria.
Fishermen's Insurance Program In Bandar Lampung City Based On An Institution Perspective
Authors: Octavia Nia , Supono Supono , Damai Abdullah Aman , Abidin Zainal , Febryano Indra Gumay
Published: February 2025

The low sustainability of participation in the Fishermen’s Insurance Premium Assistance program shows that there is an Institution issue. The research intents to analyze the institution of the fishermen’s insurance program in Bandar Lampung City. This study used the case study method as a qualitative approach. Data were obtained by in-depth interviews, participant observation, and document analysis. Analysis is used to describe institutions based on situation, structure, behavior, and performance. The results of the study show that the efforts of the insurance program in Bandar Lampung City to protect fishermen have not been achieved in the second year. This occurred because the insurance participants did not pay the premium independently or at personal expense. The fishermen are not interested in participating in insurance, in spite of the premium cost being economical. Institutions are included in the BPAN program, which plays an important role in determining the continuation of fishermen’s insurance participation. The government should consider the punishment and agreements that must be submissive by fishermen to become effective regulation. In addition, the Social Security Administrator for Employment, as an insurance provider, must accommodate the simple insurance premium payments for fishermen.
Potensi Antikanker Pada Ekstrak Etanol Makroalga Caulerpa racemosa Menggunakan Metode Brine Shrimp Lethality Test (BSLT)
Authors: Khasana Devi Ardiyati , Widiastuti Endang Linirin , Nurcahyani Nuning , Setiawan Agus , Juliasih Ni Luh Gede Ratna
Published: February 2025

Caulerpa racemosa merupakan salah satu makroalga hijau yang tersebar luas di wilayah pesisir Provinsi Lampung dan perlu dieksplorasi sebagai bahan fitofarmaka karena diduga memiliki senyawa bioaktif. Pada penelitian ini, juga menggunakan taurin yang telah diketahui dapat mencegah kerusakan sel dan jaringan akibat proses oksidatif, untuk digali potensinya sebagai antikanker. Tahap awal pada penelitian ini adalah skrining fitokimia ekstrak etanol 96% Caulerpa racemosa dan mengandung senyawa fenolik, alkaloid,  saponin, flavonoid, tanin, steroid dan terpenoid. Selanjutnya uji toksisitas ekstrak etanol Caulerpa racemosa dan taurin menggunakan metode BSLT (Brine Shrimp Lethality Test). Pada penelitian ini digunakan 7 konsentrasi, yaitu 0 ppm (kontrol); 62,5; 125; 250; 500; 1000; dan 2000 ppm baik untuk ekstrak etanol Caulerpa racemosa maupun taurin dengan 5 kali pengulangan. Nilai LC50 ekstrak etanol 96% Caulerpa racemosa sebesar 194,14 ppm dan 170,69 ppm untuk taurin, Nilai tersebut berada antara 100 ppm – 1000 ppm etanol Caulerpa racemosa dan taurin menunjukkan bahwa kedua bahan tersebut memiliki potensi aktivitas antikanker dengan toksisitas rendah.
Assessment of the Energy Intensity of Ammonia Production by Microbubbles
Authors: Kubicsek Ferenc , Hegedűs Ferenc
Published: February 2025

The present paper investigates the energy intensity of ammonia production by a freely oscillating microbubble placed in an infinite liquid domain. The spherical bubble initially contains a mixture of nitrogen and hydrogen. The bubble is expanded from its equilibrium size to a specific maximum radius via an isothermal expansion. The work needed to expand the bubble is its potential energy calculated by the sum of the work done by the internal gas, the work needed to displace the mass of the surrounding liquid, and the work needed to increase the area of the bubble against the surface tension. During the radial pulsation of the freely oscillating bubble, the internal temperature can reach several thousands of kelvin inducing chemical reactions. The chemical yield is computed by solving a set of ordinary differential equations describing the radial dynamics of the bubble (Keller—Miksis equation), the temporal evolution of the internal temperature (first law of thermodynamics), and the concentrations of the chemical species (reaction mechanism). The control parameters during the simulations were the equilibrium bubble size, the initial expansion ratio, the ambient pressure, and the initial concentration ratio of nitrogen and hydrogen. In the best-case scenario, the energy requirement in terms of GJ/t is 18.4 times higher than the best available facility of the Haber—Bosch process (assuming that the hydrogen is produced via the electrolysis of water).
Vivencias de las familias que asisten a una escuela de padres en una institución educativa, Pereira, 2023
Authors: Suárez Gaviria Lina Marcela , Henao Aragón María Valentina , Restrepo Zapata Angie Melissa , Revelo Muñoz Yuliza
Published: February 2025

Métodos: estudio cualitativo fenomenológico, muestra a conveniencia, participaron nueve personas entre padres, madres o acudientes o cuidadores, que asistieron al encuentro de Escuela de Padres convocado por la institución educativa (I. E.). Para recolectar los datos, se realizaron entrevistas semiestructuradas con guía temática, posencuentro de Escuela de Padres y previa aprobación del consentimiento informado. Resultados: al existir una buena conexión con el entorno educativo, los padres, madres y cuidadores comprendieron mejor el plan de estudios y el avance de sus hijos, sobre el aporte positivo de la Escuela de Padres, con los cuales se exploró, cómo su participación en la educación de sus hijos puede tener un impacto significativo y verdadero en su rendimiento escolar y bienestar social, familiar y emocional. Conclusiones: los padres, madres o cuidadores se sintieron involucrados y empoderados y comprendieron que desempeñan un papel fundamental en el éxito académico y personal de sus hijos.
Artificial Intelligence Promotes Educational Equity Strategy Design
Authors:   Nanjing University of Science and Technology, China, Ni Wen , Bai Lufeng ,   School of Computer Engineering, Jiangsu Second Normal University, China
Published: February 2025

This article delves into the global issue of educational equity, particularly the core problems of unequal resource allocation,
differences in educational quality, and individual differences among students. The article proposes an innovative approach
to using artificial intelligence technology to address the issue of educational equity. Through specific applications such as
data-driven decision support, personalized learning, and intelligent tutoring systems, the potential of artificial intelligence
(AI) technology in improving the efficiency of educational resource utilization and meeting individual student needs has
been demonstrated. The article not only proposes theoretical discussions, but also designs specific strategies, including
establishing AI education platforms, promoting intelligent learning tools, strengthening teacher training, and providing
policy support and funding. These strategies have strong systematicity and operability, providing practical and feasible
paths for achieving educational equity
Developing Indicators and Forecasting Demand for Enhanced Regional CommunityBased Integrated Care Systems in Japan
Authors:   Shibaura Institute of Technology, Japan, FUJITA Kaede , ICHIKAWA Manabu ,   Shibaura Institute of Technology, Japan
Published: February 2025

This study evaluates the current state and future demand of the Community-based Integrated Care System (CICS) across Japan’s
1889 municipalities. Aimed at achieving a better CICS, this research developed indicators to evaluate the existing care structures
within each municipality. Utilizing 73 indicators covering housing, medical care, long-term care, livelihood support, and preventive
services, we conducted a comprehensive analysis to identify regional disparities and strengths. The indicators were visualized
using radar charts and standardized to enable cross-regional comparisons. Future projections were made to estimate service and
personnel demands, highlighting significant regional variations and emphasizing the need for region-specific policy planning
and resource allocation. Our system allows for the evaluation and comparison of policies based on these indicators, determining
their long-term significance. This research provides critical insights for policymakers and healthcare providers, offering a solid
foundation for enhancing the CICS framework and supporting the creation of resilient, elderly-friendly communities throughout
Japan.
Community respiratory viruses are generally well-tolerated in hematopoietic stem cell transplant recipients: a brief report from the TRANSPIRE study
Authors: Haney Meghan , Ashraf Arfa , Lake Kelly E. , Strecker Lauren , Myers Kasiani C. , Towe Christopher , Walkup Laura , Woods Jason , Edwards Stephanie L. , Cooper Richard , Lehmann Leslie E. , Cisneros Gabriel Salinas , Freedman Jason L. , Baker K. Scott , Doherty Erin , MacMillan Margaret L. , Goldfarb Samuel B. , Davies Stella M. , Koo Jane , Groups TRANSPIRE
Published: February 2025

Not available.
Maintenance therapy with oral decitabine plus cedazuridine after allogeneic stem cell transplantation for myelodysplastic syndrome
Authors: Smallbone Portia , Shigle Terri Lynn , Paslovsky Oren , Hosing Chitra , Alousi Amin , Bashir Qaiser , Aljawai Yosra , Ramdial Jeremy , Popat Uday , Champlin Richard , Shpall Elizabeth J , Oran Betül
Published: February 2025

Disease relapse remains the primary challenge for patients undergoing allogeneic transplantation (HSCT) for myelodysplastic syndrome (MDS). Maintenance therapies with hypomethylating agents are under investigation for use in mitigating relapse in high-risk patients. In this retrospective study, we assessed the safety and efficacy of oral decitabinecedazuridine maintenance in 18 high-risk MDS patients post-HSCT. 66.7% (n=12) received decitabine-cedazuridine (35/100mg) on days 1 and 3, while 33.3% (n=6) received therapy on days 1-3. Patients completed a median of six treatment cycles (range; 1-20), with one third of patients completing all planned cycles. No unexpected adverse events were observed, with the primary toxicity being myelosuppression. Grade 1-2 upper respiratory tract infections occurred in 4 patients, and fungal pneumonia in one patient. Overall, patients achieved a median 2-year relapse-free survival (RFS) of 66.7% (95% CI, 40.4-83.4%) and 2-year overall survival of 72.2% (95% CI, 45.6%-87.4%), with relapses occurring predominantly in TP53- mutated cases. Prospective clinical trials are essential to confirm the best tolerated dose with potential to improve transplant outcomes.
Trends in mortality rate after cancer-related thrombosis give hope for the future
Authors: Zöller Bengt
Published: February 2025

Not available.
Principles of Nutrition Organization for Young Athletes
Authors:   International Office, State Research Center – Burnasyan Federal Medical Biophysical Center  of Federal Medical Biological Agency, Moscow, Russiа, Rylova N.V. ,   Federal scientific and clinical center for sports medicine and rehabilitation of the FMBA of Russia, Moscow, Samoylov A.S. ,   International Office, State Research Center – Burnasyan Federal Medical Biophysical Center  of Federal Medical Biological Agency, Moscow, Russiа, Zholinskiy A.V. ,   Federal scientific and clinical center for sports medicine and rehabilitation of the FMBA of Russia, Moscow, Razinkin C.M. ,   International Office, State Research Center – Burnasyan Federal Medical Biophysical Center  of Federal Medical Biological Agency, Moscow, Russiа, Kazakov V.F. ,   International Office, State Research Center – Burnasyan Federal Medical Biophysical Center  of Federal Medical Biological Agency, Moscow, Russiа
Published: February 2025

The modern problems of junior’s nutritional status are consecrated in this paper. We denoted the role of rational nutrition for athletes, as an integral part of athletic training, as well as a factor of healthy growth and development. We described the basic determining methods of athlete’s nutritional status. Also the principles and methods of nutrition and nutritional support for children – athletes are highlighted. Furthermore, we indicated to needs of various kinds of educational programs about balanced diet and dietary supplements and sports foods for junior athletes.
Pathomorphological Aspects of the Regenerative Process of Wounds Caused by the Use of Collagen Wound Coatings in Patients with Diabetic Foot Syndrome
Authors:   Federal State Budgetary Educational Institution of Higher Education “Donetsk State Medical University named after M. Gorky”, Donetsk, Russia, Lutsenko Yu.G. , Sycheva D.R. ,   Federal State Budgetary Educational Institution of Higher Education “Donetsk State Medical University named after M. Gorky”, Donetsk, Russia
Published: February 2025

Purpose: to evaluate the morphological features of the course of reparative processes in patients with diabetic foot syndrome (DFS) due to the use of collagen wound coatings.
Material and methods. the paper presents a comparative retrospective analysis of the histological material of wound tissues of 112 DFS patients. Morphological examination of the material was carried out using a microscope “Micros MC 50”, a lens “WF EWF 10x/18”. The studied material is divided into two groups: the main one is 62 micro-preparations of the wound tissue of DFS patients, collagen wound coatings (“Green Oak”, RF) were used in the complex treatment of wound defects; The control group consisted of 60 micro–preparations of wound tissues of DFS patients, local treatment of wound defects consisted of daily dressings with antiseptics and ointments.
Results and discussion. fnalysis of the obtained results showed that the use of collagen wound coatings affects each phase of the reparative process of chronic wounds of DFS patients, contributes to a faster transition from the alternativeexudative stage of inflammatory reaction in proliferative and epithelial phase; collagen absorbs wound exudate, performing a drainage function, contributing to acceleration of wound cleansing processes, reduces inflammatory reaction, normalizes the functioning of microcirculatory vessels, stabilizing blood supply in the area of wound defect and reducing hypoxia, leads to the activation of reparative processes; the use of collagen wound coatings activates the process of leukocyte migration, significantly increases the number of macrophages, promoting increased expression of proinflammatory cytokines, speeds up the process of angiogenesis, migration and proliferation of fibroblasts – granulation tissue in the wounds undergoes a maturation process much faster than the group of patients, treated with daily bandages with antiseptics and ointments.
Conclusion. the use of collagen wound coatings in the complex treatment of patients with purulent necrotic DFS forms can significantly accelerate the course of each phase of the reparative process in wound defects due to the influence of this technique granulation tissue is able to pass the process of maturation in a shorter period of time, allowing to reduce the time of preparation for plastic closure from 20-22 to 12-16 days.
Cumulative Blood Pressure: Calculation Method and Clinical Significance in Heart Failure with Preserved Ejection Fraction
Authors:   International Office, State Research Center – Burnasyan Federal Medical Biophysical Center  of Federal Medical Biological Agency, Moscow, Russiа, Posokhov I.N. ,   West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan, Yeshniyazov N.B. ,   West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan, Medovchshikov V.V. ,   West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan, Zholdin B.K. ,   West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan, Kurmanalina G.L. ,   West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan
Published: February 2025

Heart failure, a pressing issue in modern cardiology, occurs with preserved ejection fraction in more than 50% of cases. Screening and risk factor modification in HFpEF can be an effective strategy for improving long-term patient outcomes. One of the important components of such a strategy is hypertension control. Modern studies have shown that pharmaceutical control aimed not only at lowering baseline BP but also at minimizing its long-term impact leads to additional benefits for the patient, reducing cardiovascular morbidity and mortality, as well as the frequency of hospital readmissions. Our review reveals a method for calculating an indicator demonstrating the long-term impact of BP in heart failure and its clinical significance
Tasawuf Marketing: Merekonstruksi Brand Love Islami dengan Pendekatan Sufistik
Authors: Anwar Moh Muhlis
Published: February 2025

Studi ini mengeksplorasi dimensi brand love islami melalui pendekatan sufistik, bertujuan untuk memahami bagaimana prinsip-prinsip tasawuf dapat memperdalam hubungan antara konsumen dan merek syariah. Dalam kerangka sufistik, dimensi cinta seperti Hulla (persahabatan), Hawa (gairah), Ma’rifa (pengetahuan), Dzikra (kenangan), dan Ru’ya (visi) diadaptasi untuk membangun keterikatan emosional dan spiritual yang mendalam antara konsumen dan merek. Dengan mengintegrasikan prinsip-prinsip sufistik dalam pemasaran, merek syariah dapat menciptakan pengalaman yang tidak hanya memenuhi kebutuhan emosional tetapi juga resonan dengan nilai-nilai spiritual konsumen. Temuan dari studi ini menunjukkan bahwa pendekatan sufistik dapat memperkuat loyalitas dan kepuasan konsumen, memberikan wawasan baru tentang brand love dalam konteks Islam. Studi ini merekomendasikan penerapan dimensi sufistik dalam strategi pemasaran untuk membangun hubungan yang lebih berarti dan berkelanjutan antara merek dan konsumen.