bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of a health educational intervention on cardiovascular disease knowledge, motivation and behavioral skills: A cluster randomized controlled trial
Authors: Amoah John , Md. Salmiah , Rampal Lekhraj , Manaf Rosliza A , Ibrahim Normala , Amoah Lordina
Published: August 2019

Background

Cardiovascular diseases (CVD) are the number one public health challenge of the 21st century. Globally, the disease causes more deaths than any other cause. Unfortunately, many people are not aware of CVDs and its risk factors and because of this the disease burden keeps on rising. Objective of this study was to develop, implement and evaluate the effects of a health education program to improve CVD knowledge, motivation, and behavioral skills among secondary school students in Ghana.

Methods

A parallel single-blind cluster randomized controlled trial was carried out for a period of six-months with baseline and post intervention evaluations. Participants (n=848) were secondary school students of ages of 14-19 years from four schools (clusters) in Brong Ahafo, Ghana. Students in the intervention group received health education intervention whereas those of the control group received no intervention. The intervention included information on cardiovascular diseases and its risk factors, motivation, and behavioral skills modules. At six months, a follow-up data using same questionnaire were collected after the intervention was completed. The generalized linear mixed model (GLMM) was used to assess the overall effects of the intervention.

Results

Of the 848 students, 836 completed the follow-up assessment immediately after six-month. The GLMM showed the intervention was significant in improving 6.85(p<0.001), 0.90(p<0.001), 0.94(p<0.001) higher total CVD knowledge, motivation, and behavioral skills scores respectively for the intervention group when compared to the control group.

Conclusions

The intervention was effective in increasing CVD knowledge, motivation, and behavioral skills of students in the intervention arm of the study. It is recommended that the health education module be implemented into secondary schools education curricula in Ghana to improve CVD knowledge, motivation, and behavioral skills. Equipping students with the IMB will reduce CVD risk factors and prevent the onset of CVDs in future.
Comparison of Sequential feeding and Continuous feeding on Blood Glucose of critically ill patients: A non-inferiority Randomized Controlled Trial
Authors: Ren Changjie , Yao Bo , Tuo Miao , Lin Hui , Wan Xiangyu , Pang Xufeng
Published: August 2019

Objective: The goal of this study is to compare sequential feeding and continuous feeding on blood glucose of critically ill patients. Methods: A non-inferiority randomized controlled trail was adopted in this study. A total of 62 patients were finally enrolled, who were fed with enteral nutritional suspension through gastric tubes. After achieving 80% of the nutrition target calories (25kcal/kg/d) through continuous feeding, the patients were then randomly assigned into sequential feeding and continuous feeding group. In sequential feeding group, the feeding/fasting time was reasonably determined, according to the circadian rhythm of the human body in traditional Chinese medicine theory. The total daily dosage of enteral nutritional suspension was equally distributed to the three time periods of 7-9 o 'clock, 11-13 o 'clock and 17-19 o 'clock. Enteral nutritional suspension in each time period was pumped at a uniform rate within two hours by enteral feeding pump. While in continuous feeding group, patients received continuous feeding with constant velocity by enteral feeding pump during the study. Blood glucose values at 5 points (6:00/11:00/15:00/21:00/1:00) were monitored and recorded in 7 consecutive days after randomization. Meanwhile, enteral feeding intolerance was also recorded. Results: No significant demographic or physiologic differences between the sequential feeding and continuous feeding group (P >0.05). The average of glucose in sequential feeding was no inferior to continuous feeding [8.8(7.3-10.3) mmol/L vs. 10.7(9.1-12.1) mmol/L, P for non-inferiority =0.038). Hyperglycemia in CF group was more often than SF group (36.1% vs. 23.0%, P＜0.01). There was no significant differences in glucose standard deviations and Glucosemax -Glucosemin between two groups (P＞0.05). But the coefficient of glucose variation in sequential feeding group was higher than continuous feeding group [24.5(22.2-27.6) % vs. 18.9(13.7-25.3) %, P=0.013). Moreover, no significant difference in the incidence of feeding intolerance during the 7 days were found (P> 0.05). Conclusions: In this non-inferiority study, average blood glucose value of critically ill patients with sequential feeding was not higher than continuous feeding. And the feeding intolerance in sequential feeding was similar to continuous feeding.
Conditional cash transfers, uptake of maternal and child health services, and health outcomes in western rural China: A cluster controlled design
Authors: Zhou Huan , Wu Yuju , Liu Chengfang , Sun Chang , Shi Yaojiang , Zhang Linxiu , Medina Alexis , Rozelle Scott
Published: August 2019

Background: Empirical evidence suggests that the uptake of maternal and child health (MCH) services is still low in poor rural areas of China. There is concern that low uptake of MCH services may detrimentally affect child health outcomes. Previous studies have not yet identified the exact nature of the impact that conditional cash transfer (CCT) have on the uptake of MCH services and ultimately, on child health outcomes. The objective of this study is to examine the relationship between CCT, uptake of MCH services and health outcomes among children in poor rural areas of western China.

Methods: We designated two different sets of comparison villages and households that were used as comparison against which outcomes of the treated households could be assessed. We conducted a large-scale survey of 1,522 households at 75 villages (including 25 treatment and 50 comparison) from nine nationally-designated poverty counties in two provinces of China in 2014. In each village, 21 households were selected based on their eligibility status for the CCT program. Propensity score matching analyses were used to assess the impact of CCT on outcomes in terms of both Intention-to-treat (ITT) and average-treatment-effects-on-the-treated (ATT).

Results: Overall, the uptake of MCH services in the sample households were low, especially in terms of post-partum care visit, early breast feeding, exclusive breast feeding, and physical examination of the baby. The uptake of the seven types of MCH services in the CCT treatment villages was significantly higher than that in the comparison villages. Results from both the ITT and ATT analyses showed the CCT program had a positive, although small, impact on the uptake of MCH services and the knowledge of mothers about MCH health issues. Nonetheless, the CCT program had no noticeable effect on child health outcomes.

Conclusions: The CCT program generated modest improvements in the uptake of MCH services and mothers’ knowledge of MCH services in poor rural areas of Western China. These improvements, however, did not translate into substantial improvements in child health outcomes for two possible reasons: poor CCT implementation and the low quality of the rural health facilities.
The Effect of a Stress and Anxiety Coping Program on Objective Structured Clinical Examination Performance Among Nursing Students in Shiraz, Iran
Authors: Mojarrab Sadaf , Bazrafkan Leila , Jaberi Azita
Published: August 2019

ABSTRACT
Background: Nursing students experience a significant level of stress and anxiety prior to the objective structured clinical examination (OSCE). The present study aimed to evaluate the effect of anxiety coping program on the OSCE performance level of first-year nursing students in Shiraz, Iran.
Methods: The present two-stage interventional study was conducted among 76 nursing students; control group: n=35 and intervention group: n=41. Data collection instruments included a demographic characteristic form and State-Trait Anxiety Inventory (STAI) questionnaire. The intervention group followed anxiety coping program before taking the OSCE. The STAI questionnaire was filled in before and after the OSCE and the results were compared with those of the control group. The data were analysed using SPSS software (version 22.0). P<0.05 was considered statistically significant.
Results: Demographic characteristics of the participants indicated an overall homogeneity within the study population. As a result of the anxiety coping program, a substantial reduction in the anxiety score (by 11.61 units) in the intervention group was observed. There was a significant difference in the pre- and post-exam anxiety scores between the control and intervention groups (P=0.001). The anxiety coping program improved the examination results of nursing students in the final exam compared to the midterm results (an increase of 0.9487 units, P=0.001).
Conclusion: The anxiety coping program reduced the anxiety level among nursing students and improved their OSCE results. Educational planners should consider anxiety reduction strategies to help students improve their examination results.
Keywords: Anxiety, Nursing Students, State-Trait Anxiety Inventory
Safety and efficacy of intravenous oxycodone in geriatric patients undergoing general anesthesia for ophthalmic surgeries:a randomized controlled trial
Authors: Li Shuangshuang , Yao Dongdong , Hu Xiao , Li Wenxian , Tan Fang
Published: August 2019

Abstract

Background: The present study aimed to compare the safety and efficacy of intravenous oxycodone with fentanyl in geriatric patients undergoing general anesthesia for ophthalmic surgeries.

Methods: 107 geriatric patients (age 65-79 years old) with the ASA physical status 1 or 2 undergoing general anesthesia for glaucoma or retina surgeries between May 2016 and November 2017 were divided into three groups: Group O1, Group O2, and Group F. After exclusion, 105 patients were included for the final analysis, with 35 patients in each group. Oxycodone (0.1 mg/kg in Group O1, or 0.2 mg/kg in Group O2) or fentanyl (2 mcg/kg in Group F) was administered intravenously during induction of general anesthesia. Patient demographics, surgical time and anesthesia time, perioperative hemodynamic parameters and requirement of vasoactive medication, postoperative pain and requirement of rescue analgesics, postoperative sedation level and recovery time, and perioperative complications were recorded.

Results: Patients in Group O1 experienced less clinically significant hypotension compared to either Group F or Group O2. Consistently, patients in Group O1 required less intraoperative vasoactive medication (ephedrine) than those in Group F. The postoperative pain on extubation was more severe and more patients required rescue analgesia in Group F compared to Group O2, but not Group O1. The recovery time was longer and sedation level was higher in Group O2 than Group F or O1. The incidence of hypoxia during postoperative recovery was higher in Group O2 than Group F or O1.

Conclusion: Oxycodone at 0.1mg/kg can be a safe and effective application for geriatric patients undergoing general anesthesia for ophthalmic surgeries, with adequate pain control and less side effects.

Trial registration: The study was registered at http://www.chictr.org.cn , Clinical Trial Number: ChiCTR-IPR-16007927. Date of registration: February 15, 2016.

Keywords: Oxycodone, Fentanyl, Geriatric, Ophthalmology, General anesthesia
The initiation of a neuraxial analgesia service on the rate of cesarean delivery in Hubei, China. a 1-year restrospective study
Authors: ZHAO Yun , GAO YING , SUN Guoqiang , YU Lin , LIN Ying
Published: August 2019

Background

No Pain Labor &Delivery (NPLD) is a nongovernmental project to increase access to safe neuraxial analgesia through specialized training. This study explores the change of overall cesarean delivery(CD) and maternal request CD(MRCD) rate in our hospital after the initiation of neuraxial analgesia service. Methods The neuraxial labor analgesia was initiated in May 1st 2015. A multidisciplinary NPLD team from America was invited to our hospital to give education and training for 7 days. After training, the application of neuraxial labor analgesia became a routine operation in our hospital, and every parturient can choose to use neuraxial analgesia or not according to her own requirement. The rates of neuraxial labor analgesia(NA), CD, MRCD, intrapartum CD, episiotomy, postpartum hemorrhage (PPH), operative vaginal delivery and neonatal asphyxia of vaginal delivery were analyzed from May 1st 2015 to April 30th 2016. Results The rate of NA in our hospital was getting increasingly higher from 26.1% in May 2015 to 44.6% in April 2016 ( p< 0.001); the rate of CD decreased from 50.4% in May 2015 to 36.3% in April 2016 (, p< 0.001); the rate of MRCD decreased from 10.8%in May 2015 to 5.7% in April 2016( p< 0.001). There was a negative correlation between the rate of NA and that of overall CD, r=-0.803 (95%CI[-0.951,-0.642], p =0.002), and also a negative correlation between the utilization rate of NA and that of MRCD, r=-0.790 (95%CI[-0.971,-0.497], p =0.004). The rates of episiotomy, PPH, operative vaginal delivery and neonatal asphyxia in vaginal delivery women and the rates of intrapartum CD, neonatal asphyxia, and PPH in CD women remained unchanged from May 2015 to April 2016.Conclusions

Our study shows that the rates of CD and MRCD in our department significantly decreased over a year period(2015 05~2016. 04), which may be due to the increasing use of NA during vaginal delivery.
Trauma to Transformation: The Lived Experience of Bereaved Parents of Children with Chronic Life-Threatening Illnesses in Singapore
Authors: Dutta Oindrila , Tan-Ho Geraldine , Choo Ping Ying , Low Casuarine Xinyi , Chong Poh Heng , Ng Carolyn , Ganapathy Sashikumar , Ho Andy Hau Yan
Published: August 2019

Background:
In 2016, over 6.6 million children died globally, and 245 children died in Singapore. Chronic illnesses are prevalent causes of child mortality around the world. Despite growing research that examines the lived experience of parents bereaved by their child’s chronic life-threatening illness, there is no such study within the Asian context.

Methods:
To bridge this knowledge gap, meaning-oriented, strength-focused interviews were conducted with 25 parental units (i.e. 6 couples, 13 lone mothers, 4 lone fathers, and 2 primary parental figures) who lost their child to chronic life-threatening illness in Singapore (N=31), including those of Chinese (n=17), Malay (n=10) and Indian ethnicities (n=4).

Results:
Data analysis adhering to the grounded theory approach revealed 7 themes and 25 sub-themes that were organized into a Trauma-to-Transformation Model of Parental Bereavement. This model shows the major milestones in participants’ lived experience of their child’s chronic life-threatening illness and death, starting from the diagnosis of their child’s chronic life-threatening illness and the subsequent emotional turmoil (Theme 1), the mourning of their child’s death and the losses which accompanied the death (Theme 3) and participants’ experience of posttraumatic growth as an outcome of their journey (Theme 5). The model further describes the deliberate behaviors or ‘rituals’ that aided participants to regain power over their lives (Theme 2), helped them to sustain an intimate bond with their child beyond death (Theme 4), and aided participants’ transcendence of their loss by deriving positive outcomes from their experience (Theme 6). Finally, the model denotes that the lived experiences and well-being of participants were embedded within the health-and-social-care ecosystem, and in turn impacted by it (Theme 7).

Conclusions:
These themes and their corresponding sub-themes are discussed, with recommendations for enhancing culturally-sensitive support services for grieving Asian parents around the globe.
A text-mining analysis of nursing care for overseas visitors in Japan
Authors: Nishikawa Mariko , Kimura Masako Okayasu , Tsuda Yuko , Niiya Kiyoka
Published: August 2019

Background

The provision of health and nursing care for overseas visitors to Japan is becoming more important for nurses and hospitals owing to the sharp increase in visitor numbers. We investigated the attitudes and concerns of Japanese nurses when caring for overseas visitors, focusing on preparedness.

Methods

We carried out a cross-sectional text-mining study. The analysis was both qualitative and quantitative with a descriptive aim, including two open-ended questions to nurses. A total of 513 nurses participated, representing 350 hospitals from eight prefectures across Japan. We collected data from nurses enrolled in a first-level management course from August 2011 to February 2012. We analyzed the responses to the open-ended question with Text Mining Studio 5.1, and numeric data with JMP 11.0.

Results

Only 32.8% (167) of the nurses affirmed that their hospitals were prepared to care for overseas visitors. Nurses from hospitals that had prepared for overseas visitors were more concerned about culture and lifestyle differences. In contrast, nurses from hospitals that lacked appropriate preparation were strongly concerned about their foreign language skills. Among all hospitals, many nurses were most concerned about language communication, informed consent, and payment of medical expenses.

Conclusion

Hospitals in Japan should require that their nurses be better prepared to care for overseas visitors. We conclude that formal preparation will help nurses take into consideration various unique characteristics of overseas visitors to provide necessary healthcare. Japanese nursing professionals need greater knowledge of global health issues to understand patients from foreign countries.
Characterization of Lactic Acid Bacteria Isolated from the Gastrointestinal Tract of Ethiopian Rhode Island Red Chicken and their Potential Use as Probiotics
Authors: Tsega Kibrnesh Tegenaw , Maina Kagira , Berhane Nega
Published: August 2019

Background Chicken productivity and survival is affected by environmental stress and incidences of different diseases. After the ban of antibiotics growth promoters by different countries, the use of probiotics feed additives is mentioned as one alternative to antibiotics. The objective of this study was to isolate and identify potential probiotic lactic acid bacteria strains from the digestive tract content of Rhode Island Red chicken. Results The study was conducted in Gondar town of Amhara region, North West Ethiopia from November, 2018 to March, 2019. From the gastro intestinal content of 5 chicken 190 isolates were randomly selected. The isolates were identified and screened by their biochemical, morphological and 16S rRNA gene sequence. The in vitro probiotic potential of isolates was characterized by various tests. From 190 isolates 73 were found as gram positive, catalase negative and were able to grow at pH4. The bacteria were either rod (83.6%) or round (16.4%) shaped. Ten isolates were then randomly selected for further in vitro probiotic characterization due to higher cell surface hydrophobicity, good survival at pH2 and survival at 0.1% bile salt. From the 10 isolates 6 were able to survive at pH1 for 3hrs incubation. Five isolates (IS1, IS2, IS5, IS7 and IS8) were resistance to ampicillin, chloramphenicol, ciprofloxacin and erythromycin antibiotics. All the ten isolates showed antagonistic activity against Escherichia coli, Staphylococcus aureus, Salmonella typhimurium, Staphylococcus intermedius and Salmonella enteritidis. The optimum temperature for all ten isolates was 450C and all the isolates were able to grow at 0.69 mol/L of NaCl, and were able to ferment galactose, glucose, fructose, mannitol, sorbitol and sucrose. Using phylogenetic analysis of 16SrRNA gene sequence; IS3 was identified as Lactobacillus salivarius while IS4, IS6 and IS7 were identified as Lactobacillus reuteri. Conclusion The study concludes that the 10 selected isolates can be able to survive the stress conditions of gastrointestinal tract and can thus be considered as potential probiotics candidates for chickens.
Comparison of clinical manifestation, diagnosis and outcomes of invasive pulmonary aspergillosis and pulmonary mucormycosis
Authors: lin chun yu , Wang I-Ting , Chang Che‐Chia , Lee Wei-Chun , Liu Wei‐Lun , Huang Yu-Chen , Chang Ko-Wei , Huang Hung-Yu , Hsiao Hsuan-Ling , Kao Kuo‐chin , Huang Chung-Chi , Dimopoulos George
Published: August 2019

Objects

Invasive pulmonary mold infection usually has devastating outcomes. Timely differentiation between invasive pulmonary aspergillosis (IPA) from pulmonary mucormycosis (PM) is critical for treatment decision-making. However, information on IPA and PM differentiation is limited.

Methods

We conducted a retrospective, multicenter, observational study, with proven and probable IPA and PM patients from January 2004 to December 2017. Demographics, clinical manifestations, image reports, histopathological findings and outcomes were analyzed.

Results

A total of 47 IPA (34 proven and 13 probable) and 22 PM (21 proven and 1 probable) cases were analyzed. The majority of tissues (80% in IPA and 67% in PM) were obtained using bronchoscopy. While influenza infection was independently correlated to IPA, prior voriconazole exposure was independently associated with PM (p=0.036, p=0.043, respectively). The positive culture rate for PM was lower than that for IPA (41% vs. 69%, p=0.0363). The galactomannan (GM) level from serum and bronchoalveolar lavage (BAL) fluid was higher in IPA than in PM (3.1 ± 0.5 vs 0.7 ± 0.6, p=0.0313; 4.3 ± 0.6 vs. 1.5 ±1.0, p=0.0375, respectively). The overall mortality rate was 64%, which was similar among IPA and PM groups. Systemic steroid exposure and high Acute Physiology and Chronic Health Evaluation II (APACHE II) scores on admission were independently correlated to mortality in IPA (p=0.024), and concurrent bacterial sepsis predicted the in-hospital mortality among PM patients (p=0.029).

Conclusions

Influenza infection and prior exposure to voriconazole may help physicians to differentiate IPA and PM. Bronchoscopy-guided biopsy and lavage specimen provide timely and definite diagnosis. While the prognosis of IPA is associated with systemic steroid exposure and higher APACHE II scores on admission, concurrent bacterial sepsis is the only independent predictor for mortality in PM.
Shopping, Money, and Higher Values
Authors: Cicovacki Predrag
Published: August 2019

In our consumerist world, our sense of values centers around the possession of money and the possibility of buying things we have never imagined we need. Shopping has become our lifestyle and even our sense of freedom seems to reduce to a choice between the brands. I examine this state of affairs from three perspectives: apologetic, critical, and one attempting to balance our obsession with money with a proper understanding of higher values. Following Nicolai Hartmann, I attempt to explain, defend, and further develop the last of these standpoints.
Los derechos humanos a la luz del pensamiento de Juan Duns Scoto
Authors: Benítez Arias Luis Fernando
Published: August 2019

Con este aporte, quiero presentar a usted querido lector y lectora una aproximación a un problema tan cercano a nosotros en Colombia, como es el caso de los Derechos Humanos, iluminando dicha realidad desde un autor franciscano: Juan Duns Scoto, quien es recordado y celebrado este año (2008) en sus 700 años de muerte.
El trabajo informal en el Espinal-Tolima: un análisis desde la perspectiva de género
Authors: Castro Güiza Omar Ernesto , Lozano Martínez Diana del Rocío
Published: August 2019

Este estudio analiza el fenómeno del trabajo informal desde la perspectiva de género, y describe las condiciones precarias y de desprotección social en que las mujeres desempeñan este tipo de actividades, desde los resultados de investigación obtenidos sobre el caso especifico de El Espinal-Tolima.En el presente artículo se exponen los conceptos de informalidad laboral y trabajo decente, desde el marco internacional. Asi mismo, se referencian los datos más relevantes sobre el fenómeno, a nivel mundial, nacional y local y se presentan: el marco legal, los pronunciamientos gubernamentales y diversos estudios sobre el tema en Colombia que pretenden coadyuvar a examinarlo y encontrar soluciones al mismo.
O Campo Transnacional da Inovação Tecnológica e Estratégias Relacionais de Ação
Authors: Matui Paulo Cesar , Amaral Roniberto Morato do , Sacomano Neto Mário , Candido Silvio Eduardo Alvarez
Published: August 2019

O objetivo deste artigo é analisar a influência de novas tecnologias na estrutura relacional do campo da indústria automotiva. Estamos usando uma construção dos componentes fortemente conectados (Strong Connected Component- SCC) como proxy de um campo de ação. Trata-se de uma simulação fundamentada nos dados extraídos de 7.211 registros de patentes tetraédricas – patentes com prioridade registrada simultaneamente na China, EUA, Europa e Japão. Adotamos uma forma descritiva da ação estratégica num campo modelado como uma rede. A partir desta rede apresentamos os dados em painéis e buscamos identificar alterações estruturais dos grupos e da métrica nodal da intermediação. Também realizamos análise semântica para simular o padrão de escolhas dos atores acerca de concepções tecnológicas concorrentes e apresentamos os dados em painéis que identificam o padrão de escolha tecnológica antes e depois da entrada do Google. As estruturas relacionais analisadas nesta pesquisa nos mostraram que a formação de grupos hierárquicos em SCC evidencia a ação estratégica das montadoras em estabilizar o campo da inovação tecnológica. Encontramos evidências de ação relacional como forma de enquadrar a ação de concorrentes e suas escolhas. Identificamos uma participação marginal dos atores da Tecnologia da Informação e Comunicações (TIC), e que a inovação desse campo é sobretudo arquitetural.
A Presença e o Impacto de Periódicos Brasileiros da Área de Administração, Contabilidade e Turismo em Bases Científicas
Authors: Rosa Rodrigo Assunção , Romani-Dias Marcello
Published: August 2019

Rankings de periódicos elaborados por bases científicas têm influenciado pesquisadores, programas de Stricto Sensu e instituições que integram nossa academia. Diante do reduzido número de estudos de base empírica e quantitativa sobre esse tema, acessamos Web of Science (WoS), Scopus, Google Scholar, Scielo e Spell com a finalidade de respondermos a seguinte questão: Qual é a classificação dos periódicos brasileiros de Administração, Contabilidade e Turismo nas diferentes bases que calculam fator de impacto? Como resultados, notamos (i) ínfima presença e crescimento do impacto dos periódicos nas bases Scopus e Scielo, (ii) crescimento razoável na WoS, porém oriundo principalmente de autocitações, de citações nacionais de periódicos e de citações de autores brasileiros, (iii) alta correlação entre diferentes medidas de impacto, (iv) inexistência de diferença significante das médias de impacto entre alguns estratos Qualis em diferentes medidas e (v) variação considerável no impacto de um mesmo periódico em diferentes bases internacionais e nacionais.
Imprensa, Discurso Ideológico e Golpe de Estado: uma Análise Crítica do Discurso
Authors: Santos Cynthia Adrielle da Silva , Costa Alessandra De Sá Mello da
Published: August 2019

Inserido no contexto mais amplo dos estudos organizacionais históricos (Maclean, Harvey, & Clegg, 2016), o presente trabalho teve como objetivo analisar o Caderno Especial “64 – Brasil Continua” do Jornal Folha de São Paulo (FSP) à luz da análise crítica do discurso. Buscou-se compreender qual foi o posicionamento e as principais construções discursivas que o Jornal assumiu no momento do golpe civil-militar de 1964. Para tanto, construiu-se o referencial teórico sobre a participação e a colaboração da Imprensa no Golpe e na Ditadura Civil-Militar (Abreu, 2005; Capelato, 2014; Dias, 2013; Kieling, 2016; Motta, 2013; Smith, 2000). Assim, foi utilizado o quadro tridimensional de Fairclough (2016) como aporte teórico-metodológico e o arcabouço de Thompson (2011) para análise de construções ideológicas. Como principais resultados, foram identificados indícios de alinhamento do posicionamento do Jornal FSP com o golpe civil-militar de 1964 por meio de suas formações ideológicas mobilizadas pelas formas simbólicas do discurso.
Orientação e Motivação Empreendedoras: evidências do empreendedorismo religioso
Authors: Corrêa Victor Silva
Published: August 2019

Insere-se na literatura sobre Orientação Empreendedora (OE) a noção, prevalecente, de que seus atributos fundamentais – capacidade de inovação, proatividade, agressividade competitiva, assunção de riscos e autonomia – seriam empregados, essencialmente, à busca de oportunidades. No entanto, isso pode não explicar tudo. Evidências episodiais projetam luzes para o argumento de que outros motivos, ainda inexplorados pela literatura da área, poderiam se inserir aí. O presente artigo, de natureza teórico-empírica, insere-se na essência desse contexto. O objetivo é investigar fatores indutores da OE, isto é, motivações que impactam sua manifestação. Isso se faz através de duas formas principais: no âmbito teórico, ao associar à OE a literatura sobre motivações empreendedoras; no contexto empírico, ao investigar, sob abordagem qualitativa e estratégia de estudo de casos múltiplos holísticos, tipo particular de empreendedorismo, de natureza religiosa, altamente emergente e ainda pouco investigado no Brasil. Ao todo, 19 pastores neopentecostais responsáveis pela criação e condução de igrejas foram investigados. Evidências de campo permitem constatar serem os comportamentos da OE eclodidos em resposta à influência combinada de fatores associados à oportunidade, tal como já salientado pela literatura e, também, à necessidade de sobrevivência, tal como aqui identificado de maneira inovadora. Ao mesmo tempo, resultados de pesquisa permitem outras contribuições à literatura sobre OE, fornecendo-lhe interpretações inéditas.
The influence of ecological restoration projects on groundwater in Yongding River Basin in Beijing, China
Authors: Luo Zhuoran , Zhao Shuqi , Wu Jin , Zhang Yongxiang , Liu Peibin , Jia Ruitao
Published: August 2019

This study was conducted to investigate the groundwater quality features of the Yongding River in Beijing, China, and its relationship with urban development and ecological restoration projects. The Yongding River has been cut off all year around and the ecological environment has continued to deteriorate. Therefore, a series of river ecological restoration projects of ‘Five Lakes on One Route’ have been implemented. In order to characterize the physico-chemical properties of groundwater and evaluate the effects of these projects on groundwater quality, by using principal component analysis, this study analyzed spatial and temporal variation on the basis of 11 water quality parameters at 10 monitoring sites of ‘Five Lakes on One Route’ for Yongding River during April and September of 2011 and 2016. Principal component analysis demonstrated that relatively poor groundwater is mainly distributed in Fengtai District residential and industrial land, and the groundwater in Mentougou District woods is generally better. The groundwater quality at eight monitoring sites kept the same level or became better, and the construction of the river ecological restoration projects of ‘Five Lakes on One Route’ is important for protecting the groundwater resource.
The 7th Mechanized Corps (Second Formation) in memoirs of I.S. Konev
Authors: Tushkanov Igor Valentinovich , Tushkanov Dmitry Igorevich
Published: August 2019

The article analyzes the combat activity of the 7th Mechanized Corps as part of the 2nd Ukrainian front from October 1943 to January 1944. On the basis of the memoirs of the front commander, I.S. Konev, and a number of other sources, the participation of the Corps in the Novohatskoe and Kirovograd Offensive is described. The authors concluded that the 7th Mechanized Corps as a mobile reserve of the front command was used to break through a well-fortified enemy defense.
Features of the emotional sphere as a criterion of professional orientation
Authors: Podprugina Viktoriya Viktorovna
Published: August 2019

The article presents the analysis of trends in the research of emotions and phenomena associated with emotional manifestations. The article defines the role of emotions and their importance in professional activities, the relevance of the study of emotional components in the diagnosis of professional suitability, competence. The set of the emotional profile diagnostics methods taking into account levels of emotional manifestation is defined. Significant differences in the emotional profile of students of the acting department in comparison with representatives of the technical orientation are revealed. The problem of development, formation of emotional competence, namely understanding and demonstration of emotional behavior depending on the orientation, specialization in training is put forward.
Patrón espacial de riqueza específica y vacíos de representatividad de flebotominos del género Lutzomyia (Diptera: Psychodidae) en Mérida, Venezuela
Authors: Rujano María , Sánchez Mireya , Rondón Yorfer , Rondón Maritza , Nieves Elsa
Published: August 2019

Resumen Los modelos de distribución de especies son una poderosa herramienta que presentan diferentes aplicaciones.  El presente trabajo aporta los patrones de diversidad espacial de los flebotominos en el estado Mérida por medio del modelado aplicando el algoritmo de máxima entropía MaxEnt generando los mapas de distribución de riqueza específica y riqueza potencial del género Lutzomyia en el estado Mérida Venezuela y a partir de dichas distribuciones se proyectan los vacíos de representatividad que es la ocurrencia de flebotominos en áreas con insuficiente información. Para el análisis se creó una base de datos de presencia con 30 especies del género Lutzomyia (Diptera: Psychodidae) capturados en diferentes puntos georrefenciados del estado Mérida Venezuela.  Los resultados muestran que las regiones de alta riqueza específica y potencial correspondieron a la zona del valle del Mocotíes, seguida por áreas de la zona Panamericana del estado Mérida.  Mientras que los municipios pertenecientes a los Pueblos del Sur y municipios que comprenden al Páramo merideño  presentaron  los valores más bajos de riqueza específica y potencial. El análisis identificó vacíos de representatividad, espacios probables de presencia de flebotominos del género Lutzomyia en zonas sin registro de captura detectados en los municipios de los Pueblos del Sur, en municipios de la zona metropolitana y del Páramo Merideño.  Se aportan datos sobre la biodiversidad de los flebotominos en el estado Mérida  importantes para los entes de control en la prevención contra la leishmaniasis.
Intranasal Nanoparticulate Systems as Alternative Route of Drug Delivery
Authors: Alshweiat Areen , Ambrus Rita , Csóka IIdikó
Published: August 2019

There is always a need for alternative and efficient methods of drug delivery. The
nasal cavity can be considered as a non-invasive and efficient route of administration. It has
been used for local, systemic, brain targeting, and vaccination delivery. Although many intranasal
products are currently available on the market, the majority is used for local delivery
with fewer products available for the other targets. As nanotechnology utilization in drug delivery
has rapidly spread out, the nasal delivery has become attractive as a promising approach.
Nanoparticulate systems facilitate drug transportation across the mucosal barrier, protect
the drug from nasal enzyme degradation, enhance the delivery of vaccines to the lymphoid
tissue of the nasal cavity with an adjuvant activity, and offer a way for peptide delivery
into the brain and the systemic circulation, in addition to their potential for brain tumor treatment.
This review article aims at discussing the potential benefit of the intranasal nanoparticulate
systems, including nanosuspensions, lipid and surfactant, and polymer-based nanoparticles
as regards productive intranasal delivery. The aim of this review is to focus on the topicalities
of nanotechnology applications for intranasal delivery of local, systemic, brain, and
vaccination purposes during the last decade, referring to the factors affecting delivery, regulatory
aspects, and patient expectations. This review further identifies the benefits of applying
the Quality by Design approaches (QbD) in product development. According to the reported
studies on nanotechnology-based intranasal delivery, potential attention has been focused on
brain targeting and vaccine delivery with promising outcomes. Despite the significant research
effort in this field, nanoparticle-based products for intranasal delivery are not available.
Thus, further efforts are required to promote the introduction of intranasal nanoparticulate
products that can meet the requirements of regulatory affairs with high patient acceptance.
Strong Association of Serum GSK-3β/BDNF Ratio with Mild Cognitive Impairment in Elderly Type 2 Diabetic Patients
Authors: Du Bingying , Lian Yongjie , Chen Chao , Zhang Hailing , Bi Yueping , Fan Cunxiu , Bi Xiaoying
Published: August 2019

Background:

Glycogen Synthase Kinase (GSK)-3β and Brain-derived Neurotrophic Factor
(BDNF) play vital roles in both Mild Cognitive Impairment (MCI) and Type 2 Diabetes Mellitus
(T2DM). The underlying mechanisms may involve inflammation and oxidative stress.

Objectives:

To investigate the association of the GSK-3β/BDNF ratio with MCI in elderly patients with
T2DM and whether GSK-3β/BDNF ratio can serve as a new diagnostic biomarker for MCI in comorbid
with T2DM (MD).

Methods:

A total of 326 old Chinese T2DM patients were included and stratified according to cognition
and GSK-3β/BDNF ratio quartiles. MCI was diagnosed according to the National Institute on Aging
Alzheimer’s Association workgroups criteria. In addition to routine hematuria and biochemical examinations,
Montreal Cognitive Assessment (MoCA) scale was also used to evaluate the cognitive function,
and ELISA method was used to measure GSK-3β activity and the serum levels of BDNF, interleukin 1β
(IL-1β), high mobility group box-1 (HMGB1) protein, Malonaldehyde (MDA) and 8-isoprostaglandinF2α
(8-iso-PGF2α).

Results:

We found that GSK-3β activity was negatively correlated with BDNF (r=-0.270, P=0.008), and
patients with higher GSK-3β/BDNF ratio had lower MoCA scores (P=0.001). When compared with
T2DM patients without MCI (nMD), MD patients had higher GSK-3β activity and GSK-3β/BDNF ratio,
but lower BDNF levels. As for inflammation and oxidative stress, IL-1β was inversely correlated with
GSK-3β activity, while 8-isoPGF2α was positively correlated with GSK-3β activity and GSK-3β/BDNF
ratio. The odds ratio for MCI increased gradually when GSK-3β/BDNF ratio quartile rose from the lowest
to the highest (6.90, 95% CI 3.22-14.78). MoCA score was conversely related to GSK-3β/BDNF
ratio, age and fast blood glucose (FBG), with GSK-3β/BDNF ratio having the most significant influence
on cognition (β=-0.199, P<0.001).

Conclusion:

Our data provide evidence for a strong link between GSK-3β/BDNF ratio and MCI. GSK-
3β/BDNF ratio may serve as a better diagnostic biomarker for MD than either GSK-3β or BDNF alone
and increased GSK-3β/BDNF ratio indicates a worse cognitive function.
PENGARUH IKLIM KEAGAMAAN LEMBAGA PAUD TERHADAP PERKEMBANGAN NILAI AGAMA DAN MORAL ANAK USIA DINI SE-KOTA YOGYAKARTA
Authors: Syamsudin Amir
Published: August 2019

Tujuan penelitian ini untuk membuktikan pengaruh iklim keagamaan di lembaga PAUD terhadap perkembangan moral anak usia 5-6 tahun se-kota Yogyakarta. Populasi penelitian sebanyak 222 taman kanak-kanak se-Kota Yogyakarta. Sample penelitian berjumlah 143 taman kanak-kanak, dengan tingkat kesalahan penarikan sample sebesar 5%. Cara menarik sample menggunakan teknik clustered proportional random sampling. Satuan analisis penelitian meliputi iklim keagamaan di sekolah, pengalaman kerja guru PAUD, perkembangan NAM anak usia 5-6 tahun, dan persepsi kepala TK tentang kinerja guru. Responden penelitian terdiri atas kepala taman kanak-kanak, anak usia 5-6 tahun, dan guru PAUD se-kota Yogyakarta. Temuan penelitian ialah ada hubungan yang signifikan antara iklilm keagamaan di lembaga PAUD dengan perkembangan nilai-nilai agama dan moral anak usia 5-6 tahun se-Kota Yogyakarta.  Hubungan tersebut bersifat signifikan karena skor korelasi Pearson (0.772) mendekati skor 1 (korelasi sempurna) dan melampaui skor minimal korelasi ≥0.5. Hal ini mengonfirmasi sekaligus memperkuat teori bahwa iklim keagamaan berpengaruh terhadap perkembangan nilai-nilai agama dan moral anak usia dini. Kata Kunci: nilai-nilai agama dan moral, iklim keagamaan, pendidikan anak
MENGENAL UKURAN DENGAN PENDEKATAN PMRI PADA ASPEK KOGNITIF PENDIDIKAN ANAK USIA DINI
Authors: Septiana Rosmalia , Indra Putri Ratu Ilma , Hartono Yusuf
Published: August 2019

Penelitian ini bertujuan untuk menghasilkan lintasan belajar anak usia dini yang dapat membantu siswa mengembangkan aspek kognitif khususnya kemampuan mengenal ukuran. Metode yang digunakan adalah Design Research yang terdiri dari tiga tahap, yaitu : desain pendahuluan (preliminary design), desain percobaan mengajar (pilot experiment dan teaching experiment), dan analisis retrospektif. Dalam penelitian ini, serangkaian aktivitas pembelajaran didesain dan dikembangkan berdasarkan  pendekatan  PMRI. Penelitian  ini melibatkan anak usia dini dengan rentang usia 4 – 5 tahun di TK Binama Global School. Penelitian ini menghasilkan Learning Trajectory yang memuat serangkaian  proses pembelajaran anak usia dini dalam mengembangkan aspek kognitif dengan perkembangan dasar mengenal ukuran. Melalui aktivitas ini, siswa dibimbing untuk dapat mengenal ukuran melalui permainan yang disukai siswa, yaitu menuangkan air. Hasil dari penelitian menunjukkan bahwa pembelajaran dengan pendekatan PMRI dapat membantu siswa mengembangkan aspek kognitif  dengan perkembangan dasar mengenal ukuran dan menambah pengalaman belajar yang dapat diterapkan di sekitar lingkungan siswa sehari–hari.  Kata kunci : disain penelitian, pmri, paud, kognitif
IMPLEMENTASI PROGRAM LITERASI BUDAYA MELALUI SANGGAR DONGENG ANAK DI DESA MOROREJO SLEMAN
Authors: Harlistyarintica Yora , Kuffa Ririn Nikmatul , Apriyanto Sigit , Susi Susi , Cholimah Nur
Published: August 2019

Program ini bertujuan untuk menggerakkan literasi atau melek budaya (salah satu unsur budaya: sistem mata pencaharian) dengan cara mendongengkan cerita pada anak-anak. Sehingga cerita-cerita yang didongengkan untuk anak-anak seperti cerita tentang kebiasaan petani bercocok tanam ke sawah, ladang, dan beternak. Metode yang digunakan dalam program ini berupa metode dongeng, bernyanyi, bermain, tanya jawab, karyawisata, penugasan, dan demonstrasi. Kegiatan yang dilakukan berupa mendengarkan cerita, membuat media cerita, bercerita, menggambar, dan jalan-jalan/karyawisata. Sasaran kegiatan ini berjumlah 10 anak berusia 4-8 tahun dari Dusun Plumbon Tengah, Mororejo, Tempel, Sleman. Pendidik dalam kegiatan ini yaitu tim pelaksana program kreativitas mahasiswa Program Literasi Budaya melalui Sanggar Dongeng Anak. Hasil dari kegiatan ini anak mampu menggambar dan bercerita tentang budaya (salah satu unsur: sistem mata pencaharian) di Desa Mororejo. Hasil cerita anak tersebut kemudian ditulis oleh tim program kreativitas mahasiswa yang kemudian dikumpulkan untuk dibukukan. Anak-anak terlihat antusias selama mengikuti kegiatan. Orang tua sangat mendukung kegiatan ini terlihat dari keterlibatannya dalam mendampingi anak. Kata Kunci: literasi budaya, sanggar dongeng, anak
EDI SUROJO MEDIA PENGENALAN KEBUDAYAAN LOKAL BERBASIS KARAKTER UNTUK ANAK USIA DINI
Authors: Isnaini Fatimah Noor , Krahayon Metri Utami , Safitri Hana Ika , Lestari Dwi
Published: August 2019

Berdasarkan hasil wawancara dengan beberapa guru dapat disimpulkan bahwa pengenalan tokoh wayang dan cerita wayang sangat penting dikenalkan sejak dini karena dalam cerita wayang mengandung petunjuk atau teladan yang dapat diteladani oleh anak usia dini. Namun sekarang ini wayang tidak banyak dikenal karena penelitian menunjukkan bahwa para guru dan kepala TK belum memiliki kemampuan dalam mengembangkan materi dan media pembelajaran wayang serta kurangnya pemahaman guru TK tentang wayang. Oleh karena itu, perlu dirancang media untuk mengenalkan tentang tokoh wayang pada anak usia dini. Penulis membuat sebuah media berbentuk  Edi Surojo (Ensiklopedia Superhero Jowo) Tiga Dimensi sebagai Media Pengenalan Kebudayaan Lokal Berbasis Karakter Untuk Anak Usia Dini. Metode yang diterapkan dalam melaksanakan program ini merupakan sebuah rangkaian tahapan yang disusun secara sistematis, berikut adalah tahapan-tahapan yang dilakukan : Persiapan umum, pembuatan isi, dan pembuatan desain. Media seperti Ensiklopedia Superhero Jowo diharapkan dapat menjadi alternatif untuk mengenalkan kebudayaan lokal pada anak usia dini serta mengembangkan nilai-nilai pendidikan karakter melalui tokoh wayang. Potensi berkelanjutan Ensiklopedia Superhero Jowo adalah menjadi media dalam mengenalkan budaya-budaya lokal yang ada di Indonesia yaitu tokoh pewayangan. Dengan adanya Ensiklopedia Superhero Jowo dapat mempermudah guru dalam mengenalkan budaya lokal berbasis karakter pada anak usia dini. Kata Kunci: Pendidikan karakter, wayang, superhero jowo, anak usia dini
PENGEMBANGAN PAPAN FLANEL BERMAIN POLA UNTUK ANAK KELOMPOK B DI TK PERMATA BUNDA PALEMBANG
Authors: Pramitha Renny , Syafdaningsih Syafdaningsih , Sumarni Sri
Published: August 2019

Pengembangan papan flanel bermain pola untuk anak kelompok B di TK Permata Bunda Palembang telah dilakukan dengan tujuan untuk menghasilkan alat permainan papan flanel bermain pola yang valid dan praktis untuk anak kelompok B. Pengembangan dilakukan dengan menggunakan model Rowntree mencakup perencanaan, pengembangan, evaluasi. Teknik mengumpulkan data menggunakan metode wawancara, walkthrough, observasi. Pada tahap evaluasi dilakukan evaluasi formatif yang dilakukan oleh Tessmer, yaitu tahap self evaluation, expert review diperoleh nilai rata-rata dari para ahli sebesar 3,67 kategori sangat valid karena materi sesuai dengan indikator yaitu materi bermain pola yang sesuai dengan perkembangan kognitif anak kelompok B. Dari segi media juga sesuai dengan indikator yaitu bahan yang efektif dan efisien, desain tampilan, estetika. One-to-one dan small evaluation bertujuan untuk melihat kepraktisan ialah praktis jika para pakar dan praktisi menyatakan bahwa produk yang dikembangkan dapat diterapkan. Hasil tahap one-to-one evaluation dan small group evaluation dengan indikator mampu mengenal bentuk buah, mengenal konsep warna dan mengenal konsep pola diperoleh nilai rata-rata sebesar 87% kategori sangat praktis. Praktis artinya papan flanel bermain pola menarik minat anak dalam mengenal konsep pola melalui metode bermain. Kelemahan dari produk ini adalah memerlukan biaya yang besar untuk membuatnya dan sukar menempel pada benda yang berat. Untuk peneliti selanjutnya harus lebih mengembangkan papan flanel bermain pola yang dibuat dengan biaya yang murah dan memiliki daya rekat yang lebih kuat agar dapat menempelkan benda yang berat. Kata Kunci: pengembangan papan flanel, bermain pola, anak kelompok b