bluuebunny/crossref_metadata_2025 huggingface dataset:
INTERROGATING THE DISCOURSE OF POWER AND ITS RESISTANCE IN NAWAL EL SADAAWI’S GOD DIES BY THE NILE
Authors: Issaka Charity Azumi , Sanka Cofidence Gbolo , Resque Elvis
Published: February 2023

This paper employs Foucault’s theory on Discourse, Power, and Knowledge to highlight the powers shaping the Egyptian woman in God Dies by the Nile. The paper also uses the feminist theory in identifying the ways that the Egyptian woman uses to resist the discourse of power in the narrative. The paper, therefore, focuses on the power dynamics in the novel. Thus questions addressed in this paper include: how the discourses of family, society, and religion are generated in the novel; how patriarchy shapes the discourse of power in the narrative, and the subtle means used by women to resist and play out power in the novel. Using a thematic approach, textual analysis, and the novel as a primary source, the paper discusses patriarchal discourse and power politics. Examining a selection of discourses and how they affect the body of the female help in appreciating the effect of patriarchy on women in the novel. The study concludes that discourse alone does not explain the power dynamics in the novel. Silence, rebellion, female bonding, and the creation of paranoia in the men through silent but open resistance to patriarchy are some of the power dynamics played out in the novel by the female gender.
Respons pertumbuhan rimpang Jahe Merah (Zingiber officinale Var. Rubrum) pada perendaman auksin dan PGPR (Plant Growth Promoting Rhizobacteria)
Authors: Wardana Singgih Tri , Juswardi Juswardi , Rama Nanda Lian Ade
Published: February 2023

Jahe merah (Zingiber officinale Var. Rubrum) merupakan tanaman yang memiliki manfaat sebagai bahan obat herbal pencegahan COVID-19. Salah satu kendala dalam budidaya jahe merah terdapat pada masa dormansi jahe merah yaitu selama 2-4 minggu. Masa dormansi jahe merah yang panjang menyebabkan penurunan hasil produksi rimpang jahe merah. Zat pengatur tumbuh auksin dan PGPR (Plant Growth Promoting Rhizobacteria) memiliki fungsi sebagai pemacu pertumbuhan. Rancangan Penelitian yang digunakan Rancangan Acak Lengkap (RAL) dengan 4 perlakuan dan masing masing perlakuan dilakukan 6 kali pengulangan. Variabel pengamatan yaitu persentase rimpang tumbuh tunas, persentase rimpang tumbuh akar, jumlah tunas, jumlah akar, tinggi tunas, panjang akar, waktu muncul tunas dan jumlah daun. Data pertumbuhan rimpang jahe merah dianalisis dengan menggunakan ANOVA (Analysis of Varian). Apabila perlakuan berpengaruh nyata, maka akan dilanjutkan dengan uji lanjut Duncan pada α = 0,05. Hasil dari penelitian ini adalah didapatkan hasil lebih baik pada kombinasi auksin  dan PGPR terhadap  rata rata jumlah tunas 1,16, rata rata jumlah daun 0,83, waktu muncul tunas yang singkat yaitu 8,00 HST dan rata rata tinggi tunas 4,63 cm. Perendaman auksin  lebih baik terhadap rata rata jumlah akar yaitu 1,00 dan rata rata panjang akar 1,68 cm,. Persentase rimpang tumbuh tunas lebih baik pada perendaman auksin  dan PGPR yaitu 100%. Persentase rimpang tumbuh akar lebih baik pada perendaman auksin  yaitu 83,3%. Kesimpulan penelitian didapatkan kombinasi perendaman auksin  dan PGPR memberikan pengaruh lebih baik pada pertumbuhan rimpang jahe merah. Perendaman auksin  dan PGPR dapat dilakukan penelitian lebih lanjut dengan konsentrasi auksin lebih tinggi untuk mendapat hasil optimal dalam memacu akar rimpang jahe merah.
Sertralina w pytaniach i odpowiedziach
Authors: Siwek Marcin
Published: February 2023

Sertralina to lek przeciwdepresyjny z grupy selektywnych inhibitorów wychwytu zwrotnego serotoniny. W stosunku do innych substancji z tej grupy odznacza się dodatkową zdolnością do blokady wychwytu zwrotnego dopaminy do wiązania z receptorami σ1. Nie ma zaś działania antycholinergicznego lub α1-adrenolitycznego czy histaminolitycznego. Z tego powodu odznacza się bardzo korzystnym profilem tolerancji i należy do wąskiej grupy leków przeciwdepresyjnych o szczególnie korzystnym, dobrze udokumentowanym profilu bezpieczeństwa i możliwości zastosowania u pacjentów z wieloma różnymi współistniejącymi schorzeniami somatycznymi oraz u osób starszych.
Leczenie choroby zwyrodnieniowej stawu kolanowego z zastosowaniem acemetacyny
Authors: Walewska Ewa , Rell Krzysztof
Published: February 2023

Podstawowymi lekami w chorobie zwyrodnieniowej są niesteroidowe leki przeciwzapalne. Wytyczne nie wskazują żadnego preparatu jako preferowanego w rozpoczynaniu leczenia. Lek przeciwzapalny powinien być dobrany indywidualnie, w zależności od wieku pacjenta, współistniejących chorób oraz przeciwwskazań do stosowania poszczególnych preparatów. W przypadku pacjentów obciążonych czynnikami ryzyka kardiologicznego konieczne jest zapewnienie bezpieczeństwa sercowo-naczyniowego przez odpowiedni dobór leku przeciwzapalnego i/lub modyfikację farmakoterapii kardiologicznej.
Miejsce naproksenu w farmakoterapii bólu i gorączki. Co wiemy w 2022 roku?
Authors: Woroń Jarosław
Published: February 2023

Podwyższenie temperatury ciała 38°C należy traktować jak stan niepożądany i dążyć do jej obniżenia do bezpiecznego poziomu. Najczęściej stosowanymi w tym celu lekami są niesteroidowe leki przeciwzapalne, które hamują syntezę prostaglandyn pośredniczących w rozwoju stanu zapalnego. Ta grupa leków nie jest jednak jednolita pod względem efektu działania przeciwgorączkowego. Jedną z najczęściej stosowanych substancji z tej grupy jest naproksen, który wyróżnia się korzystną farmakokinetyką. Ulega on szybkiemu wchłanianiu z przewodu pokarmowego i ma obwodowy okres półtrwania 12–15 h, co gwarantuje stabilny efekt przeciwgorączkowy.
Sitagliptyna i jej miejsce we współczesnym leczeniu cukrzycy typu 2
Authors: Dzida Grzegorz
Published: February 2023

Inhibitory DPP-4 są lekami doustnymi stosowanymi w terapii cukrzycy typu 2. Poprawiają wyrównanie cukrzycy, zmniejszając odsetek HbA1c bez ryzyka hipoglikemii i przyrostu masy ciała. Są bardzo dobrze tolerowane i wykazują długotrwałą skuteczność. Sitagliptyna jest najpowszechniej stosowanym lekiem z tej klasy i wykazała bezpieczeństwo sercowo-naczyniowe w badaniu TECOS.
Komentarz
Authors: Woroń Jarosław
Published: February 2023

Brak
Warto dyskutować, warto wiedzieć. Etorykoksyb
Authors: Rell-Bakalarska Maria , Rell Krzysztof
Published: February 2023

W pracy omówiono skuteczność i działania niepożądane etorykoksybu. Etorykoksyb jest silnym niesteroidowym lekiem przeciwzapalnym stosowanym w chorobach narządu ruchu. Skuteczność leku jest porównywalna z diklofenakiem. Tolerancja leczenia jest dobra. Etorykoksyb powoduje mniej działań niepożądanych ze strony przewodu pokarmowego i wątroby niż diklofenak, pacjenci rzadziej odstawiają lek. Powikłania sercowo-naczyniowe występują z podobną częstością jak po diklofenaku. Etorykoksyb częściej powoduje wzrost ciśnienia tętniczego.
Anticonvulsant for preeclampsia: Magnesium sulfate or Diazepam ?
Authors: Serudji Joserizal
Published: February 2023

Preeclampsia is a multisystem disorder which is still the leading cause of maternal death today. The occurrence of seizures in preeclampsia (eclampsia) increases the risk of maternal and perinatal morbidity and mortality. Therefore, seizure in preeclampsia should be prevented and should be managed accurateely.The standard therapy for managing severe preeclampsia/eclampsia is the use of an anticonvulsant that is aimed to prevent/stop seizures, prevent the recurrence of attacks, to minimize and to manage their complications, and optimize the time for the birth of the baby. On the other hand, the selection of anticonvulsants needed is still controversial, so debates and studies on the effectiveness between each anticonvulsant are necessary.Comparative research between magnesium sulfate and diazepam is widely carried out, both retrospective and prospective. Magnesium sulfate is more effective than diazepam, especially in terms of overcoming seizures, and suppressing maternal mortality and perinatal morbidity, so the choice of magnesium sulfate over diazepam is more realistic.
Relationship of Dysmenorrhea and Physical Activity with Anxiety
Authors: Sumarni Een , Intasir M.Pemberdi
Published: February 2023

This study aims to determine the relationship between dysmenorrhea and physical activity with anxiety. The method used in this study is a cross sectional study. A sample of 46 biology education students class of 2021 FKIP UMRAH used a total sampling technique. The Wong Boker Pain Face was used to measure dysmenorrhea pain, the IPAQ (International Physical Activity Questionnaire ) questionnaire measured physical activity and the BAI (Beck Anxiety Inventory) questionnaire measured anxiety. Data analysis using Chi Square. The results of data analysis of dysmenorrhea with anxiety showed a p value of 0.01 (p<0.01) and the results of data analysis of physical activity with anxiety showed a p value of 0.06 (p>0.06). Thus it can be concluded that there is a significant relationship between dysmenorrhea and student anxiety and there is no significant relationship between physical activity and anxiety.
Relationship of Physical Activity to Primary Dysmenorrhea
Authors: Intasir M.Pemberdi , Sumarni Een
Published: February 2023

This study aims to determine the relationship between physical activity and primary dysmenorrhea. The method used in this study is a cross sectional study. A sample of 30 Biology Education students at Raja Ali Haji Maritime University class of 2021 used a purposive sampling technique. To measure primary dysmenorrhea using the McGill`s questionnaire, the IPAQ (International Physical Activity Questionnaire) questionnaire measures physical activity. Data analysis uses Chi Square. The results of the analysis of physical activity on primary dysmenorrhea showed a p value of 0.0 (p <0.05). Thus it can be concluded that there is a significant relationship between physical activity and primary dysmenorrhea in female students.
How antidepressants affect the cerebral ischemic injury and ischemic stroke
Authors: Sun Xiaohui , Wang Tian , Zhou Lin , Yu Yawen , Liu Zhaofeng , Ma Runchen , Fu Fenghua
Published: February 2023

Ischemic stroke is the main cause of long-term disability and death worldwide. Studies have pointed out that antidepressants not only can be used to treat depression, but also promote nerve regeneration, nerve plasticity, and recovery of nerve function after stroke. Some evidences indicated that antidepressants have beneficial effects on ischemic stroke. At the same time, there are also risks in treatment process. The mechanisms of the effects of antidepressants on ischemic stroke are complicated and rarely reported. This review summarizes the roles of antidepressants in patients and animal models of stroke, the possible mechanisms of antidepressants against brain injury induced by stroke, and the risks and challenges of antidepressants treatment in patients with ischemia.
Sauszemes transportlīdzekļu īpašnieku civiltiesiskās atbildības obligātās apdrošināšanas tiesiskie aspekti: Latvijas pieredze
Authors:   Rīgas Stradiņa universitāte, Alfejeva Jeļena
Published: February 2023

Grāmatā ir aprakstīta sauszemes transportlīdzekļu īpašnieku civiltiesiskās apdrošināšanas veida būtība un vēsturiskā attīstība, nodefinēti visi galvenie šā apdrošināšanas veida tiesību institūti, raksturots Latvijā esošais tiesiskais regulējums un tā vēsturiskā attīstība, šā regulējuma trūkumi, minēti piemēri no prakses un iezīmēti šobrīd aktuālāko problēmjautājumu risinājumi. Monogrāfija domāta visiem interesentiem, tai skaitā studentiem un praktizējošiem juristiem, kas vēlas iegūt padziļinātas zināšanas par šo apdrošināšanas veidu. Ar RSU Zinātnes padomes 21.09.2022. sēdes lēmumu grāmatai piešķirts zinātniskas monogrāfijas statuss. Atslēgvārdi: sauszemes transportlīdzekļi, transportlīdzekļu īpašnieki, civiltiesiskā atbildība, obligātā apdrošināšana.
Pharmacological efficacy of Aloe vera in wound healing: a narrative review
Authors: Aparicio Salcedo Sandra Viviana , Carranza Aldana Brian Steven , Chávez Salas Sayuri Anayca , Quispe Tinco Leslie Solanth , Palomino Zevallos Carlos Abel , Peralta Medina Ariana Nicole Peralta Medina , Robles Esquerre Juana Mónica
Published: February 2023

Aloe Vera has different therapeutic effects, including wound healing. The objective of this review is to determine the potential efficacy of the topical use of Aloe Vera in the healing of skin wounds. A bibliographic search of preclinical and clinical studies was carried out from 1999 to 2020, which included the therapeutic use of Aloe vera in the healing of: burns, surgical wounds, lactation disorders, anal fissure and anal fistula; in the databases of the VHL regional portal, PubMed and Google Scholar. It was obtained that the topical administration of Aloe vera was effective in the healing of the mentioned wounds by mainly increasing epithelization and collagen content. In conclusion, the evidence suggests that the properties and pharmacological presentation, chemical components and the effectiveness of Aloe vera to reduce the healing time of wounds make this plant a great therapeutic alternative; however, more studies are required regarding its antimicrobial property.
Depression, anxiety and stress according to belonging to a religion during pandemic in Maipú, Chile, during 2022
Authors: Hermosilla Agustín , Carreño John , Morales Ojeda Ismael Antonio
Published: February 2023

Introduction: A significant increase in the levels of depression, anxiety and stress has been found with the COVID-19 pandemic. Objective: Compare the levels of depression, anxiety, and stress due to belonging to the Adventist religion during the pandemic in residents of the Maipú commune in 2022. Methods: Cross-sectional, analytical, and correlational study, applied to a sample of 176 inhabitants of the Maipú commune in the Metropolitan Region of Chile, using the Depression, Anxiety and Stress Scale (DASS-21) to measure levels of symptoms of depression, anxiety, and stress in the population. The Mann-Whitney U test was used to compare indicators of depression, anxiety, and stress in both groups. Multivariate analyses were made through logistic regression, taking as dependent variables: stress, anxiety, and depression in a dichotomous manner. A value of p˂0.05 was considered statistically significant. Results: The Adventist population obtained better indicators, with significantly lower scores on the depression (p=0.002) and anxiety (p<0.001) subscales, but not stress (p=0.086 ). The multivariate analyses always showed a relationship between stress, anxiety, and depression (p≤0.001). A statistically significant association was found between Adventism and anxiety (adjusted OR: 3.59; 95% CI: 1.19-10.82), but not between Adventism with depression or Adventism with stress. Conclusion: A statistically significant association was found between belonging to Adventism and anxiety, where non-Adventists presented greater anxiety than Adventists; however, no association was found when assessing membership in Adventism with depression and stress.
Epidemiological-clinical characteristics and results of appendiceal plastron management in adult patients from a reference hospital in Peru
Authors: Cehua Alvarez Efrain , Delgado Garro Aaron Milton , Virú Flores Horus Michael , Roque Quezada Juan Carlos , Valdiglesias Ochoa Diana Jennifer , Nieves Cordova Luis Enrique , Quezada Gómez Gabriela
Published: February 2023

Introduction: Appendicular plastron is considered a progressive form of acute appendicitis, with a national prevalence of 2-10%. Currently management is often controversial. It is that from this context, it seeks to promote studies that can elucidate the variables associated with the management of this condition. Objective: to determine the epidemiological-clinical characteristics associated with the results of the management of the appendiceal plastron in adult patients in a reference hospital in Peru. Methods: Non-experimental study, with a quantitative approach, observational, analytical and cross-sectional design, whose sample consisted of 100 patients with a diagnosis of appendicular plastron. The data collection sheet was applied as an instrument. Likewise, a Poisson regression model was used to respond to the objectives. Results: The multivariate analysis showed that alcohol consumption (p<0.05 RPa=1.12), nausea and vomiting (p<0.05, RPa=1.48), diarrhea (p<0.05; RPa=1.08), duration of symptoms before admission between 3 and 5 days (p<0.05; RPa=1.09), appendiceal mass (p<0.05, RPa=1.18) and bandemia (p<0.05, RPa=1.12) were significantly associated with unsuccessful management results of the appendiceal plastron. Conclusion: There are epidemiological and clinical characteristics associated with the results of the management of the appendicular plastron.
Primary spinal intramedullary anaplastic ganglioglioma in a pediatric patient
Authors: Dang Huy , Khan Abdul Basit , Gadgil Nisha , Prablek Marc , Lin Frank Y. , Blessing Melissa M. , Aldave Guillermo , Bauer David
Published: February 2023

Background:

Gangliogliomas (GGs) are rare tumors of the central nervous system composed of neoplastic neural and glial cells and are typically low-grade. Intramedullary spinal anaplastic GGs (AGG) are rare, poorly understood, and often aggressive tumors that can result in widespread progression along the craniospinal axis. Due to the rarity of these tumors, data are lacking to guide clinical and pathologic diagnosis and standard of care treatment. Here, we present a case of pediatric spinal AGG to provide information on our institutional approach to work-up and to highlight unique molecular pathology.

Case Description:

A 13-year-old female presented with signs of spinal cord compression including right sided hyperreflexia, weakness, and enuresis. Magnetic resonance imaging (MRI) revealed a C3-C5 cystic and solid mass which was treated surgically with osteoplastic laminoplasty and tumor resection. Histopathologic diagnosis was consistent with AGG, and molecular testing identified mutations in H3F3A (K27M), TP53, and NF1. She received adjuvant radiation therapy and her neurological symptoms improved. However, at 6-month follow-up, she developed new symptoms. MRI revealed metastatic recurrence of tumor with leptomeningeal and intracranial spread.

Conclusion:

Primary spinal AGGs are rare tumors, but a growing body of literature shows some trends that may improve diagnosis and management. These tumors generally present in adolescence and early adulthood with motor/sensory impairment and other spinal cord symptoms. They are most commonly treated by surgical resection but frequently recur due to their aggressive nature. Further reports of these primary spinal AGGs along with characterization of their molecular profile will be important in developing more effective treatments.
Chronic epidural hematoma with frontal skull-base destruction mimicking osteogenic tumor, associated with coagulopathy due to chronic hepatitis C
Authors: Nakazato Ichiro , Tanaka Hideki , Oyama Kenichi , Onoda Keisuke , Matsuno Akira
Published: February 2023

Background:

Intracranial epidural hematoma is generally evoked by acute coup-injury. Though rare, it has a chronic clinical course and can be a non-traumatic event.

Case Description:

The patient was A thirty-five-year-old man with a complaint of one-year history of hand tremor. He was suspected diagnosis of osteogenic tumor with differential diagnosis of epidural tumor, or abscess in the right frontal skull base bone, associated with chronic type C hepatitis because of his plain CT and MRI.

Results:

Results of examinations and surgery, the extradural mass was chronic epidural hematoma without skull fracture. We diagnosis he is the rare case of chronic epidural hematoma caused by coagulopathy due to chronic hepatitis C.

Conclusion:

We reported a rare case of chronic epidural hematoma caused by coagulopathy due to chronic hepatitis C. The repeated spontaneous hemorrhage in the epidural space formed the capsule and destruction of skull base bone, just mimicking skull base tumor.
PHASE COMPLEX OF A FOUR-COMPONENT SYSTEM LiCl–KCl–Li2WO4–PbWO4
Authors: Кочкаров Ж.А. , Байсангурова А.А. , Хасбулатова З.С.
Published: February 2023

Изучена фазовая диаграмма четырехкомпонентной взаимной системы Li, K, Pb‖Cl, WO4. Проведена триангуляция его фазовой диаграммы на симплексы, выявлены древо кристаллизации и координаты эвтектической точки.

The phase diagram of the four-component reciprocal system Li, K, Pb‖Cl, WO4 has been studied. The triangulation of its phase diagram into simplices is carried out, the crystallization tree and the coordinates of the eutectic point are revealed.
GENERAL ANALYSIS OF THE CRITICAL EFFECTS OF FLOODS ON THE BIOLOGICAL COMPONENTS OF THE ECOSYSTEM OF THE MIDDLE OB
Authors: Болотнов В.П.
Published: February 2023

В статье приводится анализ критических воздействий половодий на сообщество рыб, луговой растительности, птиц, популяции ондатры, водяной полевки на выделенных участках поймы для выявления зональной изменчивости показателей предельного воздействия половодий. Для выделения критических воздействий используются графики связи показателей устойчивости и индекса воздействия половодий. Полученные характеристики могут использоваться для нормирования изменений половодий и мониторинга пойменных экосистем.

The article analyzes the critical effects of floods on the community of fish, meadow vegetation, birds, muskrat population, water vole in selected areas of the floodplain to identify zonal variability in indicators of the marginal impact of floods. To identify critical impacts, graphs of the relationship between stability indicators and the flood impact index are used. The obtained characteristics can be used to normalize changes in floodplains and monitor floodplain ecosystems.
DEVELOPMENT OF AN ALGORITHM FOR PREDICTIVE ACCOUNTING OF ENERGY RESOURCES FOR THE CALCULATOR OF ENGINEERING SYSTEMS
Authors: Шаповал А.Ф. , Мелехин А.А.
Published: February 2023

Актуальность темы обусловлена развитием цифровых технологий для решения инженерных задач, в том числе в строительной сфере. В статье представлен алгоритм прогнозного учета энергетических ресурсов для калькуляторов инженерных систем. Этот алгоритм реализован в инженерном калькуляторе вэб-приложения. В качестве реализации алгоритма используется язык программирования DHTML.

The relevance of the topic is due to the development of digital technologies for solving engineering problems, including in the construction sector. The article presents an algorithm for predictive accounting of energy resources for calculators of engineering systems. This algorithm is implemented in the web application’s engineering calculator. The DHTML programming language is used as an implementation of the algorithm.
COMPARISON OF BRAKING MODES OF ASYNCHRONOUS AND SYNCHRONOUS HYSTERETIC ELECTRIC MOTORS IN THE ELECTRIC DRIVE OF AN ELECTROMECHATRONIC DEVICE
Authors: Анисимов М.Н. , Останин С.Ю. , Антаненков А.А. , Латыпов Т.С.
Published: February 2023

Проведён сравнительный анализ режимов торможения асинхронного и синхронного гистерезисного электродвигателей в электроприводе электромехатронного устройства – рабочего механизма для современных и новых разрабатываемых машин по производству химических нитей. Показаны преимущества применения гистерезисных электродвигателей. Подтверждена точность математической модели, разработанной и использованной для проектирования гистерезисных электродвигателей.

A comparative analysis of the braking modes of asynchronous and synchronous hysteretic electric motors in the electric drive of an electromechatronic device – a working mechanism for modern and newly developed machines for the production of chemical filaments. The advantages of using hysteretic electric motors are shown. The accuracy of the mathematical model developed and used for the design of hysteretic electric motors is confirmed.
СРАВНИТЕЛЬНЫЙ АНАЛИЗ ЭЛЕКТРОПРИВОДОВ МЕХАТРОННОГО УСТРОЙСТВА НА БАЗЕ АСИНХРОННОГО И СИНХРОННОГО ГИСТЕРЕЗИСНОГО ЭЛЕКТРОДВИГАТЕЛЕЙ
Authors: Останин С.Ю.
Published: February 2023

Проведён сравнительный анализ электроприводов мехатронного устройства на базе асинхронного и синхронного гистерезисного электродвигателей для рабочих механизмов современных и новых разрабатываемых технологических машин по производству химических нитей. Показаны преимущества применения гистерезисных электродвигателей. Подтверждена точность математической модели, разработанной и использованной для проектирования гистерезисных электродвигателей.

A comparative analysis of the electric drives of a mechatronic device based on asynchronous and synchronous hysteretic electric motors for the working mechanisms of modern and newly developed technological machines for the production of chemical filaments is carried out. The advantages of using hysteretic electric motors are shown. The accuracy of the mathematical model developed and used for the design of hysteretic electric motors is confirmed.
Unveiling the Critical Role of Ion Coordination Configuration of Ether Electrolytes for High Voltage Lithium Metal Batteries
Authors: Chen Shunqiang , Fan Jiajia , Cui Zhuangzhuang , Tan Lijiang , Ruan Digen , Zhao Xin , Jiang Jinyu , Jiao Shuhong , Ren Xiaodi
Published: February 2023

Ethers with distinctive reduction stability are emerging as the promising solution to the issues of lithium (Li) metal anode. However, their inferior oxidation stability (<4.0 V vs. Li/Li+) cannot meet the ever-growing needs of high-voltage cathodes. Studies of ether electrolytes have been focusing on the archetype glyme structure with ethylene oxide moieties. Herein, we systematically vary the methylene units in the ether backbone and unveil the crucial effect of ion-ether coordination configuration on the electrolyte oxidation stability. The 1,3-dimethoxypropane (DMP, C3) molecule forms a unique six-membered chelating complex with Li+, whose stronger solvating ability suppresses undesired oxidation side reactions. In addition, the favored hydrogen transfer reaction between DMP and salt anion induces a dramatic enrichment of LiF (a total atomic ratio of 76.7%) on the cathode surface. As a result, the DMP-based electrolyte demonstrates stable cycling of nickel-rich cathodes under a high voltage of 4.7 V (87% capacity retention after 150 cycles). This study offers fundamental insights into rational electrolyte design with wide electrochemical stability window for developing high-energy-density batteries.
Telessaúde como eixo organizacional no enfrentamento ao COVID-19
Authors: Campelo Victor Eulálio Souza
Published: February 2023

A rápida progressão da pandemia do COVID-19 apresenta um verdadeiro desafio para o mundo inteiro. Uma das estratégias mais importantes para reduzir e mitigar o avanço da epidemia são as medidas de distanciamento social; nesse contexto que a telemedicina pode ajudar e fornecer suporte aos sistemas de saúde, especialmente nas áreas de saúde pública, prevenção e práticas clínicas, assim como em outros setores, como o teletrabalho e suporte em treinamento e educação. A telemedicina pode ter diferentes formas: Teleconsulta; Teletriagem; Telemonitoramento; Chatbots, tele-educação, etc. A partir desse cenário, a telessaúde pode tornar-se a organizadora do fluxo de pessoas, de informações e de insumos, inclusive financeiros, entre os pontos de atenção, qualificando o deslocamento físico de pacientes, com redução de custos e riscos. Dessa forma, garante o uso das melhores práticas assistenciais, ampliando a qualidade e aumentando a resolutividade, expandindo assim a integralidade do cuidado.
Perfil dos profissionais de saúde acometidos pela COVID19 no estado do Amapá-Norte-Brasil
Authors: Santos José Natanael Gama dos , Vasconcelos Lidiane Assunção de , Moreira Amanda Maria de Almeida , Vaz Hilton José , Arenhardt Amanda Silva , Borges Emmily Lima , Braga Stephany Siqueira , Sacramento Ruhan da Conceição
Published: February 2023

Objetivo: Realizar uma análise do perfil dos profissionais de saúde do Estado do Amapá acometidos pela COVID19 entre março a maio de 2020. Métodos: Estudo epidemiológico do tipo observacional. O local de estudo foi o estado do Amapá, situado na região Norte do Brasil. A população do estudo foi constituída por todos os profissionais de saúde do estado do Amapá que foram infectados pelo novo coronavírus no período de 23 de março a 30 de maio de 2020, com confirmação laboratorial da doença cadastradas no Sistema Gerenciador de Ambiente Laboratorial. Resultados: Os resultados demonstraram que no período de março a maio de 2020 foram infectadas 9.602 pessoas, sendo 6,0% (544) trabalhadores da saúde com a COVD-19, a categoria de enfermagem foi mais acometida representada por 42% de nível médio e 16% nível superior, o sexo feminino representa 64,5% dos afetado e a faixa etária mais relevante variou de 31-45 anos com 56% dos casos. Além de 78% dos servidores serem do setor público de saúde. Conclusão: Conclui-se que uma importante parcela de trabalhadores da área da saúde do Amapaá foi acometida pela COVID-19, assim enfatiza-se a importância de garantir proteção aos servidores dentro do ambiente hospitalar e ambulatorial.
Anais da XIII Jornada da Residência Médica da Universidade Federal do Piauí e II Jornada Científica da Residência Multiprofissional do Hospital Universitário e da Universidade Federal do Piauí
Authors: HU-UFPI Hospital Universitário
Published: February 2023

A Jornada Científica da Residência Médica e Multiprofissional da Universidade Federal do Piauí é um dos principais eventos científicos da UFPI. Nessa Jornada, os profissionais de saúde que estão concluindo seus programas de residência apresentarão pesquisas científicas de excelente qualidade, que retratam a excelência do ensino e da pesquisa científica na UFPI. Neste evento estarão reunidos todos os residentes, preceptores e supervisores dos diversos programas, compartilhando conhecimento e inovação em saúde. Convidamos todos a participarem da XIII Jornada Científica da Residência Médica da UFPI e II Jornada Científica da Residência Multiprofissional do Hospital Universitário e da Universidade Federal do Piauí prestigiarem os novos profissionais especialistas oriundos da nossa Instituição. Agradecemos a colaboração de todos que estiveram e continuam envolvidos com as Residências Médicas e Multiprofissional da UFPI.
Anais do IV International Medical Conference of Piauí, XVIII Congresso Médico do Piauí e VI Congresso da SAMPI
Authors: (SAMPI) Sociedade dos Acadêmicos de Medicina do Piauí , Associação Médica Brasileira Divisão Piauí (AMB-PI)
Published: February 2023

APRESENTAÇÃO:

O Congresso Médico do Piauí, que por anos representou o maior evento científico da classe médica do estado, teve seu projeto revitalizado em 2015, em parceria com a Associação Médica Brasileira - Divisão Piauí (AMB-PI) com a Sociedade dos Acadêmicos de Medicina do Piauí (SAMPI), para atualizá-lo conforme os modelos adotados pelas mais prestigiadas conferências do mundo. A nova proposta, que conta com uma programação dinâmica de palestras nacionais e internacionais, painéis de apresentação de trabalhos científicos e cursos práticos, revelou-se sucesso absoluto com mais de 900 resumos de artigos enviados para avaliação e 1900 inscritos nas últimas edições. O congresso possui certificação com o selo da Comissão Nacional de Acreditação (CDA), que é parte da Associação Médica Brasileira (AMB).
ANAIS DA VI MOSTRA CIENTÍFICA DE EXPERIÊNCIAS EXITOSAS EM ENFERMAGEM DO HU-UFPI/EBSERH
Authors: ALMEIDA GOMES BRAGA FRANCISCA DAS CHAGAS SHEYLA , PEREIRA COSTA JÉSSICA , DO LAGO SANTOS TÁGORA , PEREIRA DOURADO DANIELLE , ROCHA DUARTE DE CARVALHO MARIANNE , DA SILVA NASCIMENTO LYON RICHARDSON , JORGE BRANDÃO ADRIANA , SILVA VALE CAROLINA
Published: February 2023

Anualmente a Semana de Enfermagem é celebrada em todo o país entre os dias 12 e 20 de maio. Dia 12, comemora-se o Dia Mundial do Enfermeiro, em alusão ao nascimento da precursora internacional da enfermagem Florence Nightingale. E dia 20, festeja-se o Dia Nacional dos Auxiliares e Técnicos de Enfermagem em memória à Ana Néri, maior personalidade da Enfermagem Brasileira.

A Divisão de Enfermagem realiza a X Semana de Enfermagem do HU-UFPI/EBSERH e VI Mostra Científica de Experiências Exitosas em Enfermagem do HU-UFPI/EBSERH com o tema: RESSIGNIFICANDO A ESSÊNCIA, O PROPÓSITO E OS SABERES DE ENFERMAGEM.

Alinhados à missão do HU-UFPI/EBSERH de fomentar a formação de recursos humanos por meio do desenvolvimento de ensino, pesquisa e extensão, a programação da Semana de Enfermagem 2022 compreende a realização de minicursos, palestras, apresentação de trabalhos, além de atividades socioculturais extensivas aos discentes e docentes da UFPI.

A Mostra de Experiências Exitosas em Enfermagem, busca apresentar trabalhos durante a Semana de Enfermagem do HU-UFPI/EBSERH realizadas pela equipe de enfermagem, de forma individual, multidisciplinar e/ou interprofissional, que ocorrem na Instituição, bem como docentes e discentes da Universidade federal do Piauí (UFPI).
Change and Growth of Daycare Center Director through Experience of Participation in Learning Community
Authors:   Koreanisch-Deutsche Gesellschaft Fuer Erziehungswissenschaft, Seo Eunchong , Yoon Sunyoung
Published: February 2023

In this study, we qualitatively explored the changes and growth of daycare center directors through learning community participation experiences. The participants in the study were six directors of daycare centers in H city. The learning community was conducted from August 2021 to January 2022.
As a result of this study, first, problem awareness and problem solving strategies have changed at the group level. The critical mind went through busy work and problems, teachers' problems, principles and practice problems, and problems with the daycare center's operating system to find problems within themselves. The awareness of the problem turned from the outside to the inside. The problem-solving strategies were 'Utilizing breaks from work', 'Overcoming the old me', 'Breaking the old frame and rebuilding from the basics', and 'Teaching centered on teachers'. Second, individual consciousness has changed.
As a result of the analysis of individual consciousness, face-to-face, meeting/questioning, self-awareness, internal change, external change, internal/external change, and self-reflection were different for each individual. In addition, the research participants newly established 10 principles. This included the director's mental and physical management, emotional and business support for teachers, and systematic director's work management.
In this study, more active practice and self-reflection emerged as the learning community proceeded in a way that discovered problems from the director's own experience and derived practical tasks. Therefore, substantial changes and growth occurred to the research participants. Therefore, the subject reflecting the individual circumstances and demands of the director, a learning community accompanied by practice and self-reflection must be introduced as a method of re-educating the director.
Higher risk of SARS-CoV-2 Omicron BA.4/5 infection than of BA.2 infection after previous BA.1 infection, the Netherlands, 2 May to 24 July 2022
Authors: Andeweg Stijn P , de Gier Brechje , Vennema Harry , van Walle Ivo , van Maarseveen Noortje , Kusters Nina E , de Melker Hester E , Hahné Susan JM , van den Hof Susan , Eggink Dirk , Knol Mirjam J
Published: February 2023

Background

In summer 2022, SARS-CoV-2 Omicron BA.5 became dominant in Europe. In vitro studies have shown a large reduction of antibody neutralisation for this variant.

Aim

We aimed to investigate differences in protection from previous infection and/or vaccination against infection with Omicron BA.4/5 vs BA.2.

Methods

We employed a case-only approach including positive PCR tests from community testing between 2 May and 24 July 2022 that were tested for S gene target failure (SGTF), which distinguishes BA.4/5 from BA.2 infection. Previous infections were categorised by variant using whole genome sequencing or SGTF. We estimated by logistic regression the association of SGTF with vaccination and/or previous infection, and of SGTF of the current infection with the variant of the previous infection, adjusting for testing week, age group and sex.

Results

The percentage of registered previous SARS-CoV-2 infections was higher among 19,836 persons infected with Omicron BA.4/5 than among 7,052 persons infected with BA.2 (31.3% vs 20.0%). Adjusting for testing week, age group and sex, the adjusted odds ratio (aOR) was 1.4 (95% CI: 1.3–1.5). The distribution of vaccination status did not differ for BA.4/5 vs BA.2 infections (aOR = 1.1 for primary and booster vaccination). Among persons with a previous infection, those currently infected with BA4/5 had a shorter interval between infections, and the previous infection was more often caused by BA.1, compared with those currently infected with BA.2 (aOR = 1.9; 95% CI: 1.5–2.6).

Conclusion

Our results suggest immunity induced by BA.1 is less effective against BA.4/5 infection than against BA.2 infection.
ARL Annual Salary Survey 2021
Authors: Mian Anam
Published: February 2023

This report analyzes salary data for professional staff working in the 125 ARL member libraries during 2021. Data are reported for 10,751 professional staff from the 117 university ARL libraries in Canada and the United States and for 3,504 professional staff of the 8 US federal and public ARL libraries. In the Salary Survey, data for university library staff are usually reported in three distinct groups: general library systems, health sciences libraries, and law libraries.
A 90-YEAR-OLD WOMAN WITH INVASIVE LOBULAR CARCINOMA SUCCESSFULLY TREATED WITH CHEMOTHERAPY: A CASE REPORT
Authors: Borges Isabela Caldas , Vieira Luís Eduardo Matoso , Vidal David Barbosa Duarte , Melo Milena Melgaço
Published: February 2023

Invasive lobular carcinoma is the second most common type of invasive breast cancer. Specific information regarding its gold standard treatment is still very sparse, especially in older patients aged 80 years or more, or in more severe cases. Therefore, studies that show this tumor’s response to different kinds of treatment are still very necessary. A 90-year-old female patient, G5P4A1, with a familiar history of breast cancer (mother and sister), presented in March 2019 with a suspicious nodule on the right breast, measuring 2.6×1.9 cm at the physical examination. There were no palpable lymph nodes. Further investigation with ultrasound (US) showed an irregular solid hypoechoic nodule measuring 2.9×2.3 cm on the right breast, BI-RADS 6. Anatomopathological examination revealed an invasive lobular carcinoma; histologic grade II and an immunohistochemistry report indicated the expression of hormone receptors (ER+ 80%, PR+ 70%) and a cell proliferation rate (Ki-67) of 10%, whereas there was no expression of HER2. Clinical staging was T2N0MX (inoperable stage IIa). The patient then started chemotherapy with Fulvestrant + Denosumab in April 2019, with 10 sessions of this combined regimen (in April 2019, July 2019, August 2019, September 2019, November 2019, December 2019, September 2020, November 2020, December 2020, and January 2021), which was switched in 6 months (in April 2019, May 2019, June 2019, January 2020, August 2020, and October 2020) to sessions of a Fulvestrant-isolated regimen. The nodule size was evaluated with US throughout the treatment, showing constant regression: 2.2×1.8 cm (June 2019), 1.84×1.05 cm (July 2019), and 0.8×0.7 cm (September 2019 and August 2020). The chemotherapy sessions ended in January 2021, when she also had her last medical evaluation. The newest US she brought on that occasion showed that the solid nodule referred to in the most recent previous examination on the right breast had no current US expression (BI-RADS 1). The patient exhibited an excellent response to the chemotherapy. Hence, this form of treatment emerges as a valid and useful tool in the therapeutic management of invasive lobular carcinoma.
ANALYTICAL CROSS-SECTIONAL STUDY TO ASSESS THE IMPACT OF THE COVID-19 PANDEMIC ON THE STAGING OF BREAST CANCER PATIENTS
Authors: Machado Samira Juliana de Moraes , Cagnacci Neto Renato , Sonagli Marina , Iyeyasu Hirofumi , Makdissi Fabiana Baroni Alves
Published: February 2023

Introduction: We are currently living in a state of pandemic by COVID-19, whose virus has high transmissibility and potential lethality. The World Health Organization recommended social isolation, and the Brazilian National Cancer Institute, following this guidance, proposed that the oncological treatment of low-to-moderate aggressive tumors be postponed, including breast cancer. In Brazil, the lockdown was a strategy to reduce the potential impact of the pandemic on health services; consequently, asymptomatic patients postponed their imaging tests this year. Considering this abrupt change in access to health care and in the routine of cancer screening, we theorize that the COVID-19 pandemic may have had a negative impact on diagnosis, treatment, and survival in breast cancer patients. Objective: The aim of this study was to analyze the staging at diagnosis of patients with breast cancer, before and during the pandemic, and to calculate if there was a statistical difference comparing the two groups studied. A secondary objective was to describe clinical and demographic characteristics. Methods: A single-center, cross-sectional analytical study with 1219 patients diagnosed with breast cancer (CID C50 or D05) treated at the Mastology Department of the AC Camargo Cancer Center from March 2019 to February 2021. The following epidemiological variables were evaluated: age at years at diagnosis, clinical staging at diagnosis (TNM 8th edition©), presence of comorbidities (risk group for severe COVID-19), family history of cancer, symptoms at diagnosis, and provenance. Descriptive variables and data analysis was performed using Pearson’s χ2 test or Fisher’s exact test. Results: In this study, 1002 patients were included, divided into two groups: prepandemic (574) and pandemic (428). Both groups had similar demographic and clinical characteristics. There was an increase in the frequency of symptomatic patients in the pandemic period 199 (46.5%) versus nonpandemic period 213 (37.1%) (p=0.003). Anatomical and clinical staging were similar between the groups, with no statistically significant difference. When analyzing the anatomical staging, comparing the prepandemic versus pandemic groups, we observed a higher frequency of tumors: T1 [262 (45.6%) vs. 170 (39.8%), p=0.376]; N0 [398 (69.2%) vs. 288 (67.4%), p=0.194]; M0 [552 (96.0%) vs. 415 (97.2%), p=0.614]. Regarding clinical staging, early malignant tumors (EC Tis, Ia–IIIa) were more frequent, corresponding to 521 (90.8%) prepandemic versus 390 (91.1%) pandemic (p=0.766). Conclusion: There was no significant variation between the groups in terms of staging at diagnosis, but more patients with symptoms related to breast cancer sought cancer care.
ANALYSIS OF WOMEN WITH BREAST CANCER WHO UNDERWENT IMMEDIATE OR LATE BREAST RECONSTRUCTION
Authors: Ferreira Filho Darley de Lima , Ferreira Nancy Cristina Ferraz de Lucena , Ferreira Thais de Lucena
Published: February 2023

Introduction: Breast reconstruction is a right guaranteed by the public health system for women who undergo mastectomy. However, there are factors that delay the performance of this procedure in the Unified Health System in Brazil. Objective: The aim of this study was to analyze the characteristics of immediate or late breast reconstruction in women with breast cancer in a reference hospital in the state of Pernambuco. Methods: This is an observational, retrospective, analytical study, with a descriptive approach of 400 cases of breast reconstruction from 2010 to 2020. The data were collected through a surgical care survey with breast cancer patients who underwent breast reconstruction. Then, they were analyzed using the SPSS software, version 18, with the percentage rates of the categories assessed by the χ2 test, considering a 5% significance level. The comparison of the analysis was significant (p <0.005), showing that the described profile is the most frequent one in the group of assessed patients. Results: Most patients were aged between 46 and 59 years (45.3%), brown (61.1%), married (79.1%), who studied until high school (60.7%), homemakers (45%), nonsmokers (84.9%), and who do not drink alcohol (94.9%). According to the TNM system, 84% of the patients were in the early stages (0, I, and IIa), underwent immediate reconstruction after mastectomy or resection (70.3%); reconstructive surgeries had local flaps, both in the lower, upper, or medial-lateral pedicle; and implants were performed in 70% of the patients. According to the molecular subtype, Luminal A represented 60% of the patients, followed by Luminal B with 16%, triple negative with 15%, and HER-2 with 9%. Conclusion: The findings support that patients with higher schooling are prone to undergoing immediate breast reconstruction. Thus, the number of immediate breast reconstruction procedures in patients with breast cancer has increased significantly.
EVALUATION OF PATHOLOGIC COMPLETE RESPONSE, DISEASE-FREE SURVIVAL, AND GLOBAL SURVIVAL OF PATIENTS WITH BREAST CANCER, TRIPLE-NEGATIVE SUBTYPE, WHO UNDERWENT PLATINUM-BASED NEOADJUVANT CHEMOTHERAPY AT HOSPITAL DE CÂNCER DE PERNAMBUCO IN 2018–2021
Authors: Albuquerque Lucas Montarroyos Vasconcelos de , Bispo Tainan de Morais , Salgado Marcelo Ramos Tejo , Vasconcelos Carolina de Souza , Silva Gabriela Calado
Published: February 2023

Introduction: Neoadjuvant chemotherapy (NEO CT) plays an important role in the treatment of breast cancer. The main objective of this treatment was to provide better surgical results for patients who were initially considered unresectable or to enable the performance of conservative surgeries for operable patients who, due to tumor size, would be candidates for mastectomy. Besides, NEO therapy works as an in vivo sensitivity test for the applied therapy. Meta-analyses have assessed the role of pathologic complete response (pCR; ypT0/is ypN0) in relation to global survival (GS) and disease-free survival (DFS), with significantly favorable results. Objective: The aim of this study was to assess the pCR in patients with invasive breast cancer, triple-negative (TN) subtype, who underwent platinum-based NEO CT, in order to design a profile of these patients, besides assessing the DFS rate and GS rate. Method: For the description of the study population, the absolute and percentage frequency distribution was represented by mean and standard deviation when the variable presented normal distribution, and by median and interquartile interval. The applied normality test was Kolmogorov-Smirnov. The Kaplan-Meyer graph was used to analyze GS and DFS, in order to describe the survival curves. In the comparison of survival curves, according to the condition of pCR, the log-rank test was used. The analysis was conducted using the STATA software version 14.0. Results: The study was composed of 112 female patients with TN breast cancer who underwent platinum-based NEO CT, with mean age of 44.5 years; 56.2% were aged between 40 and 59 years. Most patients (96.4%) had invasive carcinoma of no special type; 54.5% at histological grade III. As for clinical staging, 33.9% were IIB, whereas 25.0% and 27.7% were IIIA and IIIB, respectively. In all, 92.0% of the patients underwent mastectomy. Almost all patients underwent radiotherapy after surgery (111/112). Only two patients presented with disease progression during CT; 57.1% had pCR; and 44.1% had partial response after NEO CT. Among women with complete response, DFS was 100% in 12 months, and 88.9% in 24 months, whereas for those who did not present pCR, the probability of DFS was 91.30% in 12 months and 78.02% in 24 months. Due to the small number of patients, we could not correlate the pCR rate with DFS and GS. Conclusion: In line with the European meta-analysis published in 2018 (ESMO), our study showed high rates of pCR after platinum-based NEO CT in patients with TN breast cancer. Contrary to data from other studies, this research could not associate pCR with improved DFS and GS.