bluuebunny/crossref_metadata_2025 huggingface dataset:
Research on Prediction of Ground Settlement of Deep Foundation Pit Based on Improved PSO-BP Neural Network
Authors: Yuhao Liu , Xiao Feng
Published: June 2021

In view of the limitations of the existing prediction methods for ground subsidence of deep foundation pit, a BP neural network prediction model based on improved particle swarm optimization algorithm was proposed. The mutation and crossover of genetic algorithm are integrated into particle swarm optimization algorithm, which makes full use of the global characteristics of genetic algorithm and the fast convergence speed of particle swarm optimization algorithm. In order to reduce the network output error, improve the convergence speed and enhance the network generalization ability, the final value of the optimized particle iteration was selected as the connection weight and threshold of the BP neural network. The results show that the RMSE, MAPE and R2 of the improved PSO-BP model are 0.3077, 0.7506% and 0.8811, so the improved PSO-BP model has a better prediction accuracy.
Finite element analysis of temporary pre-stress system of precast segmental box girder bridge
Authors: Yahui Wang , Zheng Yang , Jiangwei Kang , Zhongming Li
Published: June 2021

The precast segmental bridge has the advantages of fast construction speed, good economic performance, and small impact on the surrounding environment. In order to study the role of the temporary pre-stressing system in the cantilever assembly process of the precast segment box girder bridge, ABAQUS was used to simulate the assembly process of the standard section of a viaduct. Studying the compressive stress and relative sliding of the joint section under the action of the self-weight and temporary pre-stress, the reasonable number and spatial arrangement of the tension pedestal are determined. The research results show that too few roof pedestals will cause the large area decompression state and too much will cause the construction period to be longer. When the roof symmetrical pedestal is located on the inner side of the web, it will obviously increase the area of the zero-compression stress at the end of the top slab. When the distance between the pedestal and the center of the web is 0.12L, the full section meets the minimum consolidation pressure requirement of the glued joint. The reasonable number of tension pedestals and their spatial arrangement will provide specific guidance and reference to assembling construction of actual precast segment box girder in the future.
A Constitutive Model Incorporating Mixed Soil Slurry for Interface
Authors: Peng Kai , Wang Guohui , Liu Yaolai , Wang Xiaoliang , Liu Dong , Ma Liangliang , Bai Zhijun
Published: June 2021

In projects, mixed soil slurry between cut-off wall and coarse-grained soil always exists. It may influence on or change mechanical properties of interface between coarse-grained soil and structure. The mechanical behaviors of the interface between coarse-grained soil and concrete were investigated by simple shear tests under mixed soil slurry. The significant dilatancy and stress-strain softening can be achieved through the results, which also indicate that the cement content play an important role in the shear strength of the interface. The peak strength and the position when the dilatancy occurs are related to both normal stress and cement content. An elasto-plastic constitutive model for interface considering mixed soil slurry was formulated in the framework of generalized potential theory. The entire model parameters can be identified by experimental tests. Finally, the predictions of the model have been compared with experimental results, and results show the model is reasonable and practical.
Calculation of water environmental capacity of Puzhehei Lake
Authors: Sun Lei , Ma Wei , Ban Jing-ya , Qi De-xuan
Published: June 2021

The calculation of water environmental capacity of Puzhehei lake is of great significance for preventing water pollution and protecting water ecological environment of Puzhehei Lake Basin. Based on the lack of hydrological and water quality data in Puzhehei Lake Basin, a large number of basic data were collected through pollution source investigation and water quality monitoring. On this basis, a twodimensional hydrodynamic water quality model of Puzhehei lake was established by using Mike21 model to simulate the migration and diffusion of pollutants into the lake. The current situation of pollution load in Puzhehei lake was analyzed, and the characteristics of water flow, hydrodynamic force and the migration and diffusion law of pollutants in Puzhehei Lake were analyzed. The results show that: ①the annual loads of COD, TN, TP and NH3-N in puzhehai Lake in 2018 are 4090.0t, 401.3t, 34.4t and 122.6t; ②Puzhehei lake is mainly non-point source pollution, and the difference of water environmental capacity between non rainy season and rainy season is very significant.
General Comparison of Seismic Design between the Chinese Code and the European code
Authors: Zhiquan Ding , Zhizhao Wang , Bo Li
Published: June 2021

To promote overseas projects, it is necessary for designers to understand and distinguish the similarities and differences between the Chinese standard GB50011(Edition 2016) and the European standard EN1998. By referring to relevant papers, comparing the ground types, response spectrum, structural importance factors, seismic precaution level and seismic zoning between the GB50011(Edition 2016) and EN1998, it can be concluded that the overall seismic design concepts in the Chinese and European codes are similar but there are some small differences in ground type classification, impact of ground type on seismic action, response spectrum, importance factor, seismic precautionary criterion, seismic precautionary measures, and seismic zone.
Inversion analysis and safety evaluation of deformation of cutoff wall in Daning Reservoir
Authors: Yuan Hong-hu , Kun Liao , Yu Wang
Published: June 2021

There is a large amount of backfilled earth on both sides of the wall and the top of the lower wall of the Daning Reservoir’s cutoff wall, which is greatly disturbed by the project, and the safety of the cutoff wall needs to be evaluated. Based on the deformation law and stress condition of rigid cutoff wall during construction, according to the connection characteristics of rigid cutoff wall and plastic cutoff wall structure, the stress analysis of rigid cutoff wall is carried out by using field measurement data, so as to deduce the deformation law of plastic cutoff wall underneath, and evaluate the safety of plastic cutoff wall. The results show that the plastic cutoff wall is mainly affected by compressive stress, and the maximum compressive stress is far less than the allowable compressive stress, which indicates that the plastic cutoff wall is safe and stable during the whole construction period, although it is affected by construction and rigid cutoff wall.
Research on the Construction Path Based on the Framework of Zhejiang Territorial and Spatial Planning System
Authors: Qiu Pengcheng
Published: June 2021

In order to effectively improve the construction level of Zhejiang Province’s territorial and spatial system and its spatial governance capabilities, it is necessary to redeploy the province’s territorial and spatial planning based on the actual development of Zhejiang Province. With the rapid advancement of the urban integration work in Zhejiang Province, the increasingly prominent problems such as the deterioration of the ecological environment, the chaotic order of land use, and the large differences in regional development have made land and space development and governance more difficult. In order to effectively improve this situation, this article Taking Zhejiang Province as an example, the author discussed the basic path of constructing the framework of Zhejiang’s territorial and spatial planning system, hoping to play a certain role in promoting Zhejiang’s territorial and spatial planning.
Influence of Subway Shield Tunnel Construction on Ground Settlement
Authors: Zhang Yilei , Ma Jianxun , Cheng Dan , Li Wenxiao
Published: June 2021

Shield construction has the advantages of stable driving speed, saving manpower, and being able to carry out construction in complex strata, which has been more and more widely used. In the process of shield construction, there is a gap between shield body and segment, which is easy to cause ground settlement when the grouting speed cannot keep up. This paper summarizes the common methods to predict the surface settlement, analyzes the causes of the settlement, and lists an engineering case to illustrate the factors affecting the surface settlement. Finally, it comes to the conclusion that the main causes of the surface settlement caused by shield tunnel construction are formation loss and consolidation settlement, and the use of small cutterhead and composite cutterhead can reduce the surface settlement, It provides a reference for the development of shield construction.
The Production and Motivation Mechanism of Sports Cultural Memory Space in Urban Greenway
Authors: Qinhui Feng , Weiqiang Wang , Maalla Allam
Published: June 2021

To study the relationship between urban greenway cycling space perception and cycling behavior intention, factor analysis, correlation analysis, and regression analysis were used to conduct a questionnaire survey of 411 college students to discover the advantages and disadvantages of urban greenway cycling factor, to achieve the comparison of related indicators and dimensions. The results show that the dimensions of Guangdong urban greenway sports space perception include accessibility perception, supporting perception, service perception, and environmental spatial characteristics; Guangdong college students’ greenway cycling space perception is highly correlated with cycling behavior intention, and there is a positive correlation. Among them, the environmental spatial characteristics are the most influential factors. Greenway accessibility, supporting services, cycling landscapes, etc. can stimulate college students’ greenway cycling behavior intentions. Improving the perception of urban greenway cycling space is an effective strategy to improve college students’ greenway sports behaviour and greenway cycling behaviour.
Finite Element Analysis on Lining Structure of Diversion Tunnel in a Hydropower Station
Authors: Zhou Heng , An Xiaofan , Huang Peng , Chen Xuguang , Di Shengjie , Lu Xi , Yang Longwei
Published: June 2021

Aiming at the high internal and external water pressure tunnels built in unfavorable geological bodies, this study proposes a novel type of composite support structure in which steel plates are poured inside concrete linings. Compared with traditional structures, it has the advantages of higher tensile strength, better crack resistance, and impermeability. Taking the diversion tunnel of a hydropower station as an example, based on linear and non-linear finite element simulations, mechanical properties of the steelconcrete composite lining structure for a hydraulic tunnel in soft surrounding rocks are analyzed. On this basis, the concrete crack control under this supporting condition is verified. Research results can provide a reference for the selection of reasonable steel plate thicknesses and reinforcement types in design.
Study on Structure Design of Generator of Flood Discharge Tunnel with Level Swirling Flow
Authors: Zhou Heng , Li Hui , Liu Jing , Guo Xinlei , Wang Weiguo , Lu Xi , Di Shengjie
Published: June 2021

Through the design of the Generator of the spillway tunnel, the safe operation efficiency of flood discharge tunnel with the level swirling flow is further improved. This paper takes the horizontal swirl spillway tunnel of Gongboxia Hydropower Station on the Yellow River as an example. First, the project hub facilities of the Gongboxia Hydropower Station are introduced. Moreover, the design of the gradient section and the spinning chamber section in the Generator is also studied. Based on the calculation scheme of structural mechanics, the internal force of the structure under various load combinations such as external water pressure and internal water pressure is calculated. According to Design Codes For Hydraulic Concrete Structure, the structural reinforcement is computed. These provide the basis for the design of the flood discharge tunnel with level swirling flow of large hydropower engineering facilities in Northwest China.
The Application of Space Vector in Calculation of Plinth Elevation Angle
Authors: Deng Fang , Peng Kai , Zeng Huanying , Li Dengbo
Published: June 2021

The plinth elevation angle was related to the upstream slope and face slab shape of CFRD, as well as to the dam axis, which was very important in plinth design. Based on the space vector algorithm, the function established consists of plinth elevation angle and three-dimensional coordinate of key points of plinth line, which was taken as the unique input variable, and then the plinth elevation angle was directly obtained. The improved vector method with characteristics of high efficiency, simple input parameters and clear spatial concept, is obviously superior to the traditional geometric method which was deduce by doing the auxiliary line, and it has been widely applied and well verified in engineering.
Resilience Assessment of Urban Emergency Management for Emergencies
Authors: Xu Wang , Tianyan Wu
Published: June 2021

In recent years, urban emergency management and urban resilience have gradually become the main focus of research on the sustainable development of cities in the future due to the huge impact brought by the outbreak of epidemics and urban emergencies. Based on the Pressure-State-Response (PSR) model, this study attempts to longitudinal evaluate the time series of Xuhui District in Shanghai from the pressure layer, state layer and response layer. Based on the understanding of the current situation of the city and the change trend of the past years in advance, and combining with the urban evaluation system, a scientific conclusion is drawn that the resilience of Xuhui District of Shanghai is declining year by year, which provides a scientific basis for the decision-making of urban future development and urban resource allocation.
Research on Hysteretic Performance of Q690 High Strength Steel High-Web Box-Section Steel Column
Authors: Sun Jianpeng , Feng Wei , Guo RuiPeng , Liu Chunfeng
Published: June 2021

In this paper, the finite element simulation software ABAQUS was used to study the hysteretic performance of Q690 high-strength steel (HSS) and high-web box-section steel columns. The finite element model was established by solid elements, and the influence of the initial defects of materials on the specimen was considered. The hyteretic performance of the specimen was conducted by analyzing and comparing the width-thickness ration of the flanges and the width-thickness ration of the webs. The results show that the increase of width-thickness ratios of the webs and flanges will reduce the hysteresis performance, the energy dissipation capacity and the ultimate horizontal bearing capacity of the specimen.
Digitalization of transport sphere: relevance and main directions
Authors: Kharitonova Polina V. , Grokhotova Natalia V. , Bogdanova Evgeniya V.
Published: June 2021

The object of this study is the program of digitalization of the transport sector for the purpose of stable and effective development of the Russian economy. The subject of the research is the development of directions for the implementation of the digital economy in road transport. The working hypothesis of the study involves the construction of a systematic understanding of the role of digitalization in the transport sector in the context of improving the country’s economy through modern IT technologies. In the existing theory and practice, the idea of the role of digitalization in the transport sector for improving socioeconomic conditions needs to be clarified and supplemented. The theoretical basis of the research was the work of both domestic and foreign scientists devoted to the role of digitalization, including in the transport sector. The information base was the data of the Federal State Statistics Service, legal acts of Russia, information obtained at all-Russian and international conferences devoted to the problems of introducing the digital economy in various spheres of life. The article presents its own vision of the concept of “digital economy”, substantiates the relevance and significance of the process of digitalization of the transport sector. The main directions of introducing the digital economy into the provision of services for the transportation of goods and passengers by road are proposed, the implementation of which will ensure stable and effective development of not only the transport industry, but also the country’s economy as a whole.
Assessment improvement of road accidents on highways of the Far North as the basis for sustainable regional development
Authors: Skorobogatchenko Dmitry A. , Borovik Vitaly S. , Borovik Vitaly V. , Zhabunin Anton Y. , Chugumbaev Roman R.
Published: June 2021

The paper substantiates the need to assess the road safety in the specific conditions of the Far North by means of the analysis of the factors in the “driver-car-road-environment” system. The authors suggest a methodology for assessment of road traffic accidents, which makes it possible to take into account a wide range of factors affecting road accidents. In particular, the simulation takes into account the characteristics of the driver, technical condition of the vehicle, road conditions, weather and climate. Adaptive neural networks based on fuzzy inference systems are used as a tool for road safety assessment. The authors mention the results of statistical studies on a number of variables of the “driver-car-road-environment” system, which make it possible to form membership functions in the fuzzy inference system. The final part of the paper presents the practical results of road safety assessment for various categories of drivers in different road conditions in one of the largest cities in the Far North.
Training of specialists for transport construction in the context of digitalization
Authors: Zhygadlo A , Poleshchenko K , Kodentseva Yu
Published: June 2021

The main goal of the study is to determine the direction of transformation of “SibADI” FSBEI HE as a center of attraction for all concentrated knowledge, skills and abilities in the development of the road industry, within the framework of the development conditions established by the scientific and technological revolution. This takes into account synchronization of all efforts on the part of scientific communities and industrial partners. Today, the Siberian State Automobile and Highway University faces the task of transforming from an industry-specific university with an accumulated scientific base. It includes transport construction, into an entrepreneurial University with commercialization of scientific, technical and educational and results in the following areas: “Creation and testing of intelligent composite materials”; “Creation of automated complexes for modeling multicomponent new road materials, including those of technogenic soils”; “Informational modeling of road objects with data transmission system”; “New methods of road diagnostics and defect recognition”; “Digital control, monitoring, forecasting systems”; “Intelligent logistics and design of network road configurations, as well as the development and transfer of entrepreneurial competencies into educational сontent”. The specificity of training of engineers requires reaching a qualitatively new level, which makes it possible to enter the number of international recognized specialized universities, to solve ambitious tasks.
Innovations in Russian tourism: ethno-tourism and sharing model
Authors: Polukhina Anna N. , Agalakova Oksana S.
Published: June 2021

This paper aims to shed light on the prospects of ethno-tourism cluster development in Russian regions. The provided methodology is applicable for the study of the cluster approach in the field of tourism. The focus is made on good practices of ethno-clusters in tourism in the Russian regions. There are some scientific methods in this research: methods of the system and comparative analysis, a technique of assessment of resources and capacity of regions, methods of administrative diagnostics, expert estimates, a deep interview, methods of social research will be applied. Tools of a research include (depending on a solvable task): dialectic, formal and logical, concrete historical, structurally functional and statistical methods. Moreover, authors research a new economy model – sharing – and its influence of tourism area. The main results are the challenges and prospects for ethno-tourism development are defined and supported by Mari El case study. The factors exerting influence on ethno-tourism development include tourism potential of the region; attitude of ethnos and local authorities to tourism; availability of the necessary infrastructure and qualified personnel and new information technology. The conditions facilitating success of the tourism cluster development are analyzed. These include, first of all, the development of the target programme for tourism development with the emphasis on ethno-tourism on the level of local authorities; secondly, investment in tourism infrastructure development; thirdly, the sharing model will contribute to establish the ethno-tourism cluster. The research is of practical importance for modernization of domestic tourism programmes in order to boost regional economy.
Industrial symbiosis as an element of sustainable development of arctic companies
Authors: Nikonorov Sergei , Utkina Ekaterina
Published: June 2021

Economic activity in the Arctic is playing an increasingly important role in the globalizing economy, given that such an economy is largely based on natural resources (oil, gas and minerals) as well as the long-distance transport of these resources and related goods. The Arctic seems to be one of the last opportunities to exploit vast resources, which, ironically, made it possible by the negative effects of this very exploitation in the form of global warming and the subsequent retreat of the ice cover of the circumpolar North. Thus, the Arctic has already become and will continue to be part of economic globalization. The article gives an analysis of the dynamics of the «Polar Index of the Barents region. Companies». The need to include the main elements of industrial safety in the sustainable development of the Arctic has been justified, as well as the establishment of industrial symbiotic cooperation rating based on it. Industrial symbiosis is an economically efficient and environmentally friendly solution for industry that reduces energy consumption and primary material consumption by deriving value from waste, byproducts and heat losses.
The place of the concept of ‘human security’ in the strategies of the Arctic countries
Authors: Lagutina Maria
Published: June 2021

This paper is devoted to determination of the place of the concept of ‘human security’ in the modern strategies of the Arctic countries. The article examines the formation of the concept of ‘human security’, the features of human security in the Arctic, as well as the place of the idea of human security in the modern Arctic policy of Russia. Today, the Arctic, being a ‘zone of peace and stability’ in the categories of traditional security, faces a complex of new challenges and threats related to ‘human security’. The author analyses the strategic documents of the eight Arctic countries with a view to reflect the ideas of human security in them. Special attention is paid to human security’s issues in the AZRF. In conclusion, the author points out that none of the strategies of the eight Arctic countries explicitly mentions the term ‘human security’. But at the same time, some elements of this concept are undoubtedly noted in strategic documents: the priority of most Arctic countries is economic security and environmental security, while the rest of the components of human security are found only in certain countries’ strategies.
Modern problems of Evenk language functioning and its development prospects
Authors: Andreeva Tamara , Struchkov Kirill
Published: June 2021

The article is dedicated to the modern problems of Evenk language functioning and its development prospects. The preservation and development of the language remain an urgent sociolinguistic and sociocultural problem to this day. The research conducted in Yakutia shows that the functioning of Evenk language is reduced to a minimum. The linguistic situation with the native language is assessed as definitely critical and can be one of the indicators of socio-economic ill-being of not only Evenks, but also other indigenous peoples. The main problems of linguistic life in the republic include the reduction of Evenk language functions and inadequate formation of a positive motivation for learning the native language. In the society, there is a complex system of objective and subjective factors that do not contribute tointensive development of positive processes in the preservation and development of Evenk language. In general, subjective factors include poor organization of the educational process in educational institutions, ineffectiveness of training sessions, insufficient attention to the development of speech culture and enrichment of the native language’s vocabulary, low level of educational and methodological support of education and upbringing. The social environment for Evenk language functioning is continuing to narrow, which makes an objective factor.
Language rights and education of the small numbered indigenous peoples of the European North of Russia: from the Soviet period to modern time
Authors: Atnashev Vadim , Leete Art , Komelina Natalya , Bildyug Arina , Eltc Elena
Published: June 2021

The article examines the experience of Russian constituent entities (Murmansk region, Nenets Autonomous Okrug, Archangelsk Oblast) in the support of indigenous ethnocultural rights in the context of current models for protection of minority languages and initiatives in the field of education. The contemporary scene of interaction between the state and indigenous minorities in the region is considered from a historical perspective. Special attention is paid to the early decades of the Soviet regime when key discussions concerning the status, way of integration with the state and direction of cultural development were established. The cultural bases and boarding schools, collectivization, forced relocations contributed to the construction of social reality of indigenous peoples which we can observe in the post-Soviet period. The specificity of modern transformation in the sphere of language and life of the reindeer herders are discussed in the context of the everyday practices of the interethnic relations of the Nenets and the Pomors of the Kanin peninsula and the northern parts of Mezen Region.
International and national practice for estimating cash expenditures of road replacement, repair and maintenance
Authors: Gogolev V , Barysheva M
Published: June 2021

The paper considers the importance of the uninterrupted functioning of the transport network, which is the most important condition for eliminating the transport inaccessibility of Arctic territories of the regions, thus excluding transport discrimination of the population living in the Arctic zone of the Russian Federation. Besides, the paper provides a brief overview of international road repair and maintenance experience on the example of Norway, analysis of the standard for repair and maintenance of roads in the Russian Federation, proposals on the method of calculating the cash expenditures of replacement, repair and maintenance of roads in the Russian Federation. The Decree of the Government of the Russian Federation No. 658 dated May 30, 2017 approved the standards of financial expenditures and the rules for calculating the size of federal budget allocations for replacement, repair and maintenance of federal roads. However, at the moment, not all regions have updated the regulatory framework on the norms of financial expenditures and the rules for calculating budget allocations for replacement, repair and maintenance of regional and inter-municipal roads. The existing methodology for calculating the cost of repair and maintenance of roads in the Arctic territory of Russia does not fully provide the need to bring the existing roads into normal transport and operational condition for their safe operation. The analysis shows that there is no systematic work to ensure sustainable financing of the road economy in the republic and the road industry is financed at a level much lower than the actual needs.
Memorial narratives and symbolic images as a resource for the development of Northern urban space
Authors: Khokholova Irena , Danilova Natalia , Tomaska Alyona , Pestereva Kyunney
Published: June 2021

The article is devoted to the identification of symbolic markers and perception of the cognitive model of the space of the northern cities of the Republic of Sakha (Yakutia). The definition of “northern cities” is constructed based on the results of a study to identify various aspects of identity (national, territorial, ethnocultural) and is used by the authors when defining all cities of Yakutia. The main tools for constructing and regulating the cognitive map of a city are city monuments associated with historical memory and acting as components of state policy and a nation-building tool. The main research methods were historical and cognitive analysis and the method of questionnaire survey. The novelty of the article is a cross-cultural study of the perception of urban monuments as symbolic markers of urban space. The authors observe a difference in the perception of the symbolism of urban space between generational groups. It is concluded that each city, depending on its geographical and economic location, local characteristics, and national identity, has its own specific set of symbolic markers in the cognitive map of the city. The findings will contribute to the systematic study of the value attitudes of residents of modern Russian cities. Multilevel models of symbolic images associated with both national and territorial identities are being built.
State support of JSC “Russian railways”
Authors: Krushinskaia Olga I. , Manchenko Natalia V. , Dinets Daria A. , Artemev Dmitriy S.
Published: June 2021

The main sources of funds for railway investment projects in Russia are still state and regional budgets, funds from the National Welfare Fund, the net profit of Russian Railways, and pension savings from the Pension Fund of Russia. The reform of the system of the Ministry of Railways and the creation of JSC “Russian Railways”, which began in 2016, has not yet released the state budget from financing its needs, and there has been no active use of private investment. Moreover, the monopoly began to seek to shift the financing of not only the modernization and construction of tracks, but even the maintenance of existing infra-structure on the shoulders of the state and shippers. From year to year, there is an increase in the total amount of state support for Russian Railways. Part of the received state support funds in the period under review is spent inefficiently by JSC “Russian Railways”. The remaining budget funds that are not used by JSC “Russian Railways” additionally burden the economy, increasing inflation by various surcharges to tariffs, but the available budget funds are not selected in full, and billions of fines are paid for this. There are low rates of implementation of individual investment projects, overestimation of expenses for the purchase of equipment, an increase in the cost of construction, the cost of contracts for a number of objects exceeds the cost determined by state expertise, etc.
Economic efficiency of the introduction of the automated locomotive reliability management system
Authors: Olentsevich Viktoriya A. , Kondratiev Viktor V. , Kuznetsov Boris O. , Karlina Antonina I.
Published: June 2021

Railway transport has its characteristic features: a specific investment structure, its relatively high capital intensity and duration of implementation of innovative projects, technological continuity of the production process, and much more. The specified features are also appropriate to service locomotive depots and actively influence the development of methodological approaches to assessing the economic efficiency of innovative projects. Of course, the main task of innovative projects is not to increase their number, but to increase the long-term efficiency of the transport company. To achieve this goal, according to the authors, it is advisable to use the balanced scorecard (BSC), which is an element of the company’s strategic management, but it must be adapted to innovative projects. The use of the balanced scorecard in the service locomotive depot of the railway transport system will allow the industry to reach a new level of functioning and make it possible to assess the economic efficiency of innovative projects as objectively and accurately as possible. The proposed methodology for assessing the effectiveness of an innovative project makes it possible, on the one hand, to economically justify the project, on the other hand, to monitor production efficiency both for the purposes of the project itself and to stimulate the innovative activity of the enterprise. With that, the result of an innovative project is considered not as static, but as a set of indicators for its implementation, which has specific dynamic, economic, financial, technical, technological and other characteristics.
Use of a digital platform in the selection of socially significant projects (through the example of the lisp in the Yakutia)
Authors: Ushnitskaya L , Feofanova A
Published: June 2021

The relevance of the research issue is explained by the global transition to digital format. Under the conditions of digitalization of all spheres of life, it turned out to be necessary to conduct a digital dialogue between state executive authorities and population. The Republic of Sakha (Yakutia), being the leading region of the implementation and development of IT technologies in the Far East, has introduced the use of a digital platform to resolve local matters. The paper discusses the experience of the implementation of the Local Initiatives Support Program. The transformation of the program was studied, taking into account the specific features of the republic, the presence of the Arctic territories in it, as well as the use of a digital platform as a tool to improve the implementation of programs.
Rapid Implementation of Remote Online Patient Portal Activation in a Children's Hospital during the COVID-19 Pandemic
Authors: Vuong Kim T. , Rungvivatjarus Tiranun , Garcia Isabel P. , Lewis Cindy , Miller Lisa , Kuelbs Cynthia L.
Published: June 2021

Background Patient portal access allows more patient engagement, yet portal usage is not universal. Telemedicine visits became critical when the coronavirus disease 2019 (COVID-19) pandemic limited in-office visits. Given physical distancing requirements and telemedicine platform integrated into the patient portal, our institution needed to rapidly enroll patients and their proxies remotely, including hospitalized patients, to minimize care disruptions.

Objectives The study aimed to describe the rapid implementation of remote patient portal activation in a pediatric integrated delivery network during the COVID-19 pandemic. Additionally, to increase the percentage of patients with active portal status upon discharge by 15% (absolute change) across inpatient units within 3 months.

Methods A multidisciplinary taskforce utilized quality improvement tools to identify barriers to successful inpatient patient portal activation followed by rapid intervention cycles to effect change. Weekly progress was monitored on a portal activation dashboard.

Results We created clinical decision support tools and training within 2 weeks. Active patient portal status upon hospital discharge increased from 44 to 66% within 12 weeks. Online patient portal conversion within 7 days after hospital discharge increased from 6.0 to 24%. Offer rate increased from 73 to 85% across all inpatient units.

Conclusion We rapidly and effectively implemented a remote proxy portal activation process in the inpatient setting. Remote activation, training, clinical decision support, multidisciplinary involvement, and emphasis on the portal as integral to ongoing care allowed us to dramatically increase portal conversion. This experience may be informative for pediatric hospitals aiming to increase proxy portal enrollment and adult hospitals with medical decision-making proxies.
Lessons Learned for Identifying and Annotating Permissions in Clinical Consent Forms
Authors: Umberfield Elizabeth E. , Jiang Yun , Fenton Susan H. , Stansbury Cooper , Ford Kathleen , Crist Kaycee , Kardia Sharon L. R. , Thomer Andrea K. , Harris Marcelline R.
Published: June 2021

Background The lack of machine-interpretable representations of consent permissions precludes development of tools that act upon permissions across information ecosystems, at scale.

Objectives To report the process, results, and lessons learned while annotating permissions in clinical consent forms.

Methods We conducted a retrospective analysis of clinical consent forms. We developed an annotation scheme following the MAMA (Model-Annotate-Model-Annotate) cycle and evaluated interannotator agreement (IAA) using observed agreement (A o), weighted kappa (κw ), and Krippendorff's α.

Results The final dataset included 6,399 sentences from 134 clinical consent forms. Complete agreement was achieved for 5,871 sentences, including 211 positively identified and 5,660 negatively identified as permission-sentences across all three annotators (A o = 0.944, Krippendorff's α = 0.599). These values reflect moderate to substantial IAA. Although permission-sentences contain a set of common words and structure, disagreements between annotators are largely explained by lexical variability and ambiguity in sentence meaning.

Conclusion Our findings point to the complexity of identifying permission-sentences within the clinical consent forms. We present our results in light of lessons learned, which may serve as a launching point for developing tools for automated permission extraction.
Application of Risk Scores for Hepatocellular Carcinoma in Patients with Chronic Hepatitis B: Current Status and Future Perspective
Authors: Hsu Yao-Chun , Tseng Cheng-Hao , Huang Yen-Tsung , Yang Hwai-I
Published: June 2021

Accurate risk prediction for hepatocellular carcinoma (HCC) among patients with chronic hepatitis B (CHB) may guide treatment strategies including initiation of antiviral therapy and also inform implementation of HCC surveillance. There have been 26 risk scores developed to predict HCC in CHB patients with (n = 14) or without (n = 12) receiving antiviral treatment; all of them invariably include age in the scoring formula. Virological biomarkers of replicative activities (i.e., hepatitis B virus DNA level or hepatitis B envelope antigen status) are frequently included in the scores derived from patients with untreated CHB, whereas measurements that gauge severity of liver fibrosis and/or reserve of hepatic function (i.e., cirrhosis diagnosis, liver stiffness measurement, platelet count, or albumin) are essential components in the scores developed from treated patients. External validation is a prerequisite for clinical application but not yet performed for all scores. For the future, higher predictive accuracy may be achieved with machine learning based on more comprehensive data.
The Expression of Recombinant Human Serum Albumin in the Mammary Gland of Transgenic Mice
Authors: Gong Gui-Hua , Han Shu , Huang Xiao-Ling , Xie Li-Ping , Zhang Wei , Xu Lei , Hu You-Jia
Published: June 2021

Human serum albumin (HSA) is widely used in the clinic for the treatment of several diseases in large amount each year. With the increasing demands of HSA in clinic and limited blood resource, recombinant HSA (rHSA) is becoming an attractive and alternative source for HSA production. In this study, we aimed to express rHSA in the mammary glands of transgenic mice by using a tissue-specific promoter and other regulatory elements. An rHSA expression vector was constructed bearing the cDNA and first intron of HSA under the control of bovine αs1-casein promoter with a 2 × chicken β-globin insulator in the front. Transgenic mice were generated and reverse transcription polymerase chain reaction showed that rHSA was expressed only in the mammary gland, indicating the tissue specificity of the bovine αs1-casein promoter in directing transgene transcription in transgenic mice. Enzyme-linked immunosorbent assay test showed that rHSA was successfully secreted into the milk of transgenic mice with the highest level at 1.98 ± 0.12 g/L. Our results indicate the ability of the bovine αs1-casein promoter to induce successful expression of rHSA in the mammary gland of transgenic mice.
Neonatal Atypical Hemolytic Uremic Syndrome in the Eculizumab Era
Authors: Gomes Sara Madureira , Teixeira Rita Pissarra , Rocha Gustavo , Soares Paulo , Guimaraes Hercilia , Santos Paulo , Jardim Joana , Barreira João Luís , Pinto Helena
Published: June 2021

The atypical hemolytic uremic syndrome (aHUS) in the newborn is a rare disease, with high morbidity. Eculizumab, considered a first-line drug in older children, is not approved in neonates and in children weighing less than 5 kg. We present a 5-day-old female newborn, born at 36 weeks' twin gestation, by emergency cesarean section due to cord prolapse, with birth weight of 2,035 g and Apgar score of 7/7/7, who develops microangiopathic hemolytic anemia, thrombocytopenia, and progressive acute renal failure. In day 5, after diagnosis of aHUS, a daily infusion of fresh frozen plasma begins, with improvement of thrombocytopenia and very slight improvement in renal function. The etiologic study (congenital infection, Shiga toxin, ADAMTS13 activity, directed metabolic study) was normal. C3c was slightly decreased. On day 16 for maintenance of anemia and severe renal failure, she started 300 mg/dose eculizumab. Anemia resolves in 10 weeks and creatinine has normal values after 13 weeks of treatment. The genetic study was normal. In this case, eculizumab is effective in controlling microangiopathy and in the recovery of renal function. Diagnosis of neonatal aHUS can be challenging because of phenotypic heterogeneity and potential overlap with other manifestations that may confound it, such as perinatal asphyxia or sepsis/disseminated intravascular coagulation.
Synthesis of a Novel PTH1–34 Analog with Increased Human Serum Albumin Affinity
Authors: Ruan Si-Da , Dong Yuan-Zhen , Lu Jian-Guang , Zhao Meng-Jia , Lu Wei-Gen , Feng Jun
Published: June 2021

Parathyroid hormone (PTH)1–34 is an effective peptide drug for osteoporosis therapy. However, the half-life of PTH1–34 in vivo is short, leading to the need for frequent injections of this drug during its treatment. To prolong the half-life of PTH1–34, a novel PTH1–34 analog was generated based on fatty acid generation, and its synthesis process included recombinant protein expression, side-chain modification, and peptide decoration. The PTH1–34 variant was expressed in Escherichia coli, with a single Lys (position 27) retained as a modification site. The side chain, –AEEA-γGlu-C18 diacid, was synthesized using 2-chlorotrityl chloride resin as a solid support, and then was conjugated to the PTH1-34 variant to form PTH-Lys27-AGC. Reversed-phase chromatography confirmed a high final purity (>98%) of the target compound; in vitro bioactivity tests showed that PTH-1 receptor potency of PTH-Lys27-AGC was comparable to that of the native PTH1–34. A competitive human serum albumin binding test demonstrated a high albumin affinity of PTH-Lys27-AGC in comparison to PTH1–34. In summary, we developed a novel PTH1–34 analog, PTH-Lys27-AGC, which may be a long-acting agent for osteoporosis treatment in the future.
Nursing Attitudes and Practices in Code Documentation Employing a New Electronic Health Record
Authors: Whalen Kimberly , Grella Pat , Snydeman Colleen , Dwyer Ann-Marie , Yager Phoebe
Published: June 2021

Objective Based on feedback from nurses regarding the challenges of code documentation following the implementation of a new electronic health record (EHR), we sought to better understand inpatient nurse attitudes and practices in code documentation and to identify opportunities for improvement.

Methods An anonymous electronic survey was distributed to all inpatient nurses working at a single, 999-bed, university-based, and quaternary care hospital. Participation in the study was voluntary and consent was implied by survey completion.

Results Overall, 432 (14%) of 3,121 inpatient nurses completed the survey. While nearly 80% of respondents indicated feeling very comfortable using computers for personal use, only 5% felt very comfortable navigating the EHR to document codes in real time. While 53% had documented codes in the new EHR, most admitted to documenting on paper with retroactive entry into the EHR. About 25% reported having participated in a code that was not accurately documented in the new EHR. All respondents provided specific suggestions for improving the EHR interface, and over 90% expressed interest in having opportunities to practice code documentation using simulated code events.

Conclusion Despite completion of training modules in code documentation in a new EHR, many inpatient nurses in a single institution feel uncomfortable documenting codes directly into the EHR, and some question the accuracy of this documentation. Improving EHR functionality based on specific recommendations from end-users coupled with more practice documenting simulated codes may ease EHR navigation, leading to nurses' acceptance of the EHR tool, more accurate and efficient documentation, greater nurse satisfaction and more appropriate quality improvement measures.
Price-related consumer discussions in China and the United States: a cross-cultural study investigating price perceptions and word-of-mouth transmission
Authors: Schneider Sebastian
Published: June 2021

Prices are among the most frequently discussed topics in consumer research. Although word-of-mouth is known to be highly influential and it is considered to be of growing importance, previous research has largely neglected price-related word-of-mouth, especially in a cross-cultural context. The present study fills this research gap by analyzing the effects of price-related word-of-mouth valence, price changes communicated by word-of-mouth, market mavenism and national culture on price fairness and expensiveness perceptions, as well as on subsequent word-of-mouth intentions. Two studies employing Hofstede’s national culture dimensions reveal considerable differences between the cultures of the United States and China.
Down from the “Ivory Tower”? Not so much…Italian political scientists and the constitutional referendum campaign
Authors: Vicentini Giulia , Pritoni Andrea
Published: June 2021

Academics are often accused of being secluded in their “ivory towers”, focused on research and teaching but uninterested in, or unable to engage with, the public debate. If this is actually the case, under what conditions and at what particular moment is this likely to change? Following on three relevant dimensions—the visibility of political scientists, their partisanship and their impact in the public sphere—and combining press analysis with original survey data, this article has two main aims: first, to assess Italian political scientists’ (IPSs) social relevance in a period of huge political and institutional conflict such as the constitutional referendum held in December 2016; second, to explore the potential factors leading IPSs to be more or less present in the public debate. For the former, we focus on the public visibility of IPSs during the referendum campaign, as well as on the content of their public interventions, both concerning their neutral/partisan stance and their attitudes towards the constitutional reform. For the latter, we empirically test a few personal and institutional factors that are likely to influence individuals’ participation in the referendum debate.