bluuebunny/crossref_metadata_2025 huggingface dataset:
Recent Advances in the Synthesis and Analysis of Atorvastatin and its Intermediates
Authors: Li Shu-Fang , Zhang Wei , Zhang Wen , Huang An , Zhu Jia-Qi , Wang Ya-Jun , Zheng Yu-Guo
Published: October 2023

:

Atorvastatin, a lipid-lowering drug that is widely used in the treatment of cardiovascular
diseases, has significant clinical significance. This article focuses on the synthetic
procedures of atorvastatin, including Paal-Knorr synthesis and several new synthetic
strategies. It also outlines chemical and chemo-enzymatic methods for synthesizing optically
active side chain of atorvastatin. In addition, a comprehensive overview of the analytical
monitoring techniques for atorvastatin and its metabolites and impurities is reported,
alongside a discussion of their strengths and limitations.
Communicative (inter-)action transcending the police investigative interview room
Authors: Zürcher Franziska Hohl , Capus Nadja
Published: October 2023

Police officers anticipate the evidential function and the absentaudience while interviewing and recording investigative interviews. Thisaudience consists of judges charged with taking procedural decisions based,among other things, on their reception of these written records. Qualitativestudies have revealed that interviewers use confrontational questions tocommunicate their doubt regarding the interviewee’s credibility to the audience,and that they formulate the questions in the written record more confrontationallythan in the actual interview for the same reason. However, so far, insufficientknowledge exists about the intended effect: Is the audience receptive to thepolice officer’s doubt when reading the written record? Our paper reportsan experiment testing the effects of this confrontational questioning style. Theresults show that there is, indeed, a communicative (inter-)action transcendingthe police investigative interview room: the audience is receptive to the policeofficer’s doubt transmitted via the questioning style reported in the writtenrecord
Primer registro de Sclerocactus papyracanthus (Cactaceae) en México
Authors: Ortiz-Brunel Juan Pablo , Delladdio Aldo , Raya-Sánchez Ricardo Daniel , Pérez-Badillo Cristian , Zurita-Suárez Iván , Flores Joel
Published: October 2023

Antecedentes y Objetivos: Sclerocactus (Cactaceae) es un género que comprende 27 taxones principalmente distribuidos en el sur de los Estados Unidos de América y el norte de México. Sclerocactus papyracanthus es una especie muy distintiva debido a sus espinas centrales papiráceas y aplanadas, y a su forma de crecimiento similar a la de algunos pastos. Su distribución actual conocida es en los estados de Arizona, Nuevo México y Texas en el sur de los Estados Unidos de América, cerca de la frontera con México. Sin embargo, detectamos una posible observación de esta especie en Chihuahua en la plataforma Naturalista. Derivado de esto, nuestros objetivos fueron encontrar individuos de S. papyracanthus en México, describir su morfología, sus preferencias ecológicas y documentar la ocurrencia de la especie en México con ejemplares de herbario, fotografías e ilustraciones.Métodos: Usando la ubicación reportada en la observación de Naturalista, se realizaron dos exploraciones en el estado de Chihuahua a principios de 2023 para buscar la especie. Se encontró una población de cactus similares a S. papyracanthus. Se tomaron fotografías, mediciones morfológicas y datos del hábitat y se prepararon ejemplares de herbario. Los datos ecológicos y morfológicos obtenidos fueron comparados con aquellos reportados en literatura científica y en otros ejemplares de herbario disponibles.Resultados clave: Las comparaciones morfológicas corroboraron que la población de Sclerocactus encontrada corresponde a S. papyracanthus y la presencia de la especie en México fue confirmada. Se encontraron un total de 38 plantas de varios tamaños. Además, se documentaron dos individuos juveniles floreciendo.Conclusiones: Actualmente en México, S. papyracanthus se conoce solo de una localidad de pastizales en el municipio de Ascensión, Chihuahua. Se necesitan más exploración e investigación para complementar el conocimiento de las preferencias ecológicas y la distribución de la especie en México.
Examining the Persuasive Effects of Health Communication in Short Videos: Systematic Review
Authors: Zhu Zicheng , Liu Shiyu , Zhang Renwen
Published: October 2023

Background

The ubiquity of short videos has demonstrated vast potential for health communication. An expansion of research has examined the persuasive effect of health communication in short videos, yet a synthesis of the research is lacking.

Objective

This paper aims to provide an overview of the literature by examining the persuasive effect of health communication in short videos, offering guidance for researchers and practitioners. In particular, it seeks to address 4 key research questions: What are the characteristics of short videos, samples, and research designs in short video–based health communication literature? What theories underpin the short video–based health communication literature? What are the persuasive effects of health communication in short videos? and What directions should future research in this area take?

Methods

Following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, an electronic search of 10 databases up to March 10, 2023, generated 4118 results. After the full-text screening, 18 articles met the eligibility criteria.

Results

The current research lacks a uniform definition of short videos, demonstrates sample biases in location and education, and adopts limited methodologies. Most studies in this synthesis are theoretically grounded or use theoretical concepts, which are predominantly well examined in persuasion research. Moreover, relevant topics and suitable themes are effective in persuasive health communication outcomes, whereas the impact of diverse narrative techniques remains ambiguous.

Conclusions

We recommend that future research extends the definition of short videos beyond time constraints and explores non-Western and less-educated populations. In addition, researchers should consider diverse methods to provide a more comprehensive examination and investigate the impact of audience targeting and narrative techniques in short video health communication. Finally, investigating how the unique aspects of short videos interact with or challenge traditional persuasion theories is essential.
Public Perceptions About Monkeypox on Twitter: Thematic Analysis
Authors: Leslie Abimbola , Okunromade Omolola , Sarker Abeed
Published: October 2023

Background

Social media has emerged as an important source of information generated by large segments of the population, which can be particularly valuable during infectious disease outbreaks. The recent outbreak of monkeypox led to an increase in discussions about the topic on social media, thus presenting the opportunity to conduct studies based on the generated data.

Objective

By analyzing posts from Twitter (subsequently rebranded X), we aimed to identify the topics of public discourse as well as knowledge and opinions about the monkeypox virus during the 2022 outbreak.

Methods

We collected data from Twitter focusing on English-language posts containing key phrases like “monkeypox,” “mpoxvirus,” and “monkey pox,” as well as their hashtag equivalents from August to October 2022. We preprocessed the data using natural language processing to remove duplicates and filter out noise. We then selected a random sample from the collected posts. Three annotators reviewed a sample of the posts and created a guideline for coding based on discussion. Finally, the annotators analyzed, coded, and manually categorized them first into topics and then into coarse-grained themes. Disagreements were resolved via discussion among all authors.

Results

A total of 128,615 posts were collected over a 3-month period, and 200 tweets were selected and included for manual analyses. The following 8 themes were generated from the Twitter posts: monkeypox doubts, media, monkeypox transmission, effect of monkeypox, knowledge of monkeypox, politics, monkeypox vaccine, and general comments. The most common themes from our study were monkeypox doubts and media, each accounting for 22% (44/200) of the posts. The posts represented a mix of useful information reflecting emerging knowledge on the topic as well as misinformation.

Conclusions

Social networks, such as Twitter, are useful sources of information in the early stages of outbreaks. Close to real-time identification and analyses of misinformation may help authorities take the necessary steps in a timely manner.
Examining the Persuasive Effects of Health Communication in Short Videos: Systematic Review (Preprint)
Authors: Zhu Zicheng , Liu Shiyu , Zhang Renwen
Published: October 2023

BACKGROUND

The ubiquity of short videos has demonstrated vast potential for health communication. An expansion of research has examined the persuasive effect of health communication in short videos, yet a synthesis of the research is lacking.

OBJECTIVE

This paper aims to provide an overview of the literature by examining the persuasive effect of health communication in short videos, offering guidance for researchers and practitioners. In particular, it seeks to address 4 key research questions: What are the characteristics of short videos, samples, and research designs in short video–based health communication literature? What theories underpin the short video–based health communication literature? What are the persuasive effects of health communication in short videos? and What directions should future research in this area take?

METHODS

Following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, an electronic search of 10 databases up to March 10, 2023, generated 4118 results. After the full-text screening, 18 articles met the eligibility criteria.

RESULTS

The current research lacks a uniform definition of short videos, demonstrates sample biases in location and education, and adopts limited methodologies. Most studies in this synthesis are theoretically grounded or use theoretical concepts, which are predominantly well examined in persuasion research. Moreover, relevant topics and suitable themes are effective in persuasive health communication outcomes, whereas the impact of diverse narrative techniques remains ambiguous.

CONCLUSIONS

We recommend that future research extends the definition of short videos beyond time constraints and explores non-Western and less-educated populations. In addition, researchers should consider diverse methods to provide a more comprehensive examination and investigate the impact of audience targeting and narrative techniques in short video health communication. Finally, investigating how the unique aspects of short videos interact with or challenge traditional persuasion theories is essential.
Letter of Editor-in-Chief
Authors: Author No
Published: October 2023

No abstract
Structural and functional state of bone in patients with arteriovenous malformations of the lower extremities
Authors: Zyma A.M. , Vyderko R.V. , Kincha-Polishchuk T.A. , Cheverda A.I. , Chernukha L.M. , Guk Yu.M. , Haiko O.G. , Magomedov O.M. , Zotya A.V. , Skuratov O.Yu.
Published: October 2023

Background. Disruption of regional blood flow in patients with arteriovenous malformations (AVMs) of the lower extremities changes the conditions of bone tissue functioning. The purpose was to study the structural and functional state of bone tissue and its metabolism in patients with AVMs of the lower extremities using dual-energy X-ray absorptiometry and the markers of bone turnover. Materials and methods. Fifteen patients with AVMs had been examined. The clinical class of chronic venous disease (CVD) was evaluated according to CEAP; patients were divided into 2 subgroups: the first one was with CVD C1-C3 and the second one was with CVD C4-C6. Bone mineral density (BMD) was studied based on the X-ray absorptiometry. The level of bone metabolism markers, such as procollagen type 1 N-terminal propeptide (P1NP), C-terminal cross-linking telopeptide of type 1 collagen (β-CTx) and osteocalcin, 25-hydroxyvitamin D (25(ОН)D) and parathyroid hormone were studied. Results. Disturbances of the bone tissue indices of the affected limb were found in 70 % of the patients. Also, the statistically significant difference in BMD of the affected limb compared to the healthy limb was established (р = 0.005). A multidirectional level of P1NP was detected; β-CTx exceeded norm in 80 % of the patients; osteocalcin exceeded norm in 33 % of the cases. In 67 % of the patients, a decrease in serum level of 25(OH)D was noted. Increase of the β-CTx level in the first subgroup and its decrease in the second one was associated with stabilization of the AVMs course and age-related changes in the hormonal background of the patients. Conclusions. Disturbances in the structural state of bone tissue of the affected limb were found in 70 % of the patients; statistically significant difference between the BMD of the affected and healthy limb obviously caused by the influence of regional hemodynamic disturbances. Various deviations of the metabolism markers were found, which indicates the need to develop a system of drug therapy.
Particularities of upper extremity fractures in patients with COVID-19
Authors: Tanasiienko P.V. , Skobenko Y.O.
Published: October 2023

Background. Treatment of the fractures in patients with COVID-19, given the novelty of this problem, is one of the most difficult tasks of modern traumatology and orthopedics. The purpose of this study was to determine the peculiarities of the course of the traumatic process in victims with fractures of the upper limbs against the background of COVID-19. Materials and methods. To carry out our research, we retrospectively analyzed the treatment of 136 trauma patients who underwent inpatient treatment in one of the city hospitals of Kyiv from 2019 to 2021. In our study, we used the generally accepted AO/ASIF classification of fractures to determine the clinical and nosological characteristics of injuries in patients with COVID-19. Results. During the COVID-19 epidemic, fractures to the distal part of the forearm (28.8 %), clavicle (17.8%) and proximal part of the shoulder (15.1 %) were most often detected. Among segmental injuries in patients with COVID-19, forearm (in 42.5 % of cases) and shoulder (in 35.6 % of cases) fractures predominated. Also, simple fractures of type A (72.6 %) were more common, and much less fragmentary fractures of type B (21.9 %) and multifragmentary type C fractures (5.5 %) were present. It is worth noting a significant decrease in the number of hand injuries during the COVID-19 pandemic by almost 7 times. In our opinion, this is due to the lockdown introduced by the authorities of Ukraine, which significantly reduced the number of industrial injuries among the research sample. Conclusions. We concluded that the COVID-19 pande­mic significantly affected the clinical and nosological structure and characteristics of bone fractures of the upper limb girdle, the analysis of cases proved that such changes in the clinical and nosological structure of fractures of the upper limb girdle are associated with changes in life activities during the pandemic and more typical for domestic trauma.
Dermatosparaxis type of Ehlers-Danlos syndrome: case report
Authors: Balatska N.I. , Stroi O.A. , Grynevych I.V. , Husynin P.V. , Medvedieva O.P. , Kyrylchuk K.Yu.
Published: October 2023

Background. The dermatosparaxial type of Ehlers-Danlos syndrome (EDSDERMS, VIIC, dEDS) is an extremely rare disorder. To date, 15 patients with this type of Ehlers-Danlos syndrome are known worldwide. The purpose was to improve knowledge and spread data about the orphan connective tissue di­sease — dEDS — on the example of a patient from a family in which the father and two sons have the same type of lesions. Materials and methods. We report a 6-year-old patient as well as his father and sibling with clinical symptoms of the dEDS, which we diagnosed based on the main diagnostic criteria: extreme skin fragi­lity, craniofacial features, superficial skin trauma, wrinkling of the palms, especially when they are exposed to water for a long time, and a tendency to ecchymosis with a risk of subcutaneous hematomas and bleeding. Secondary diagnostic criteria were represen­ted by atrophic scars, refractive errors (myopia), gingival margi­nal dysplasia, hypermobility of the finger and knee joints. The informed consent of the patient’s parents was obtained for the exa­mination and publication of information, and the parents agreed to the publication of clinical photographs. Results. After laboratory and instrumental studies and consultations with related specialists (hematologist, geneticist, cardiologist, pediatrician, orthopedist, dermatologist), we excluded such diseases as Marfan syndrome, MASS-phenotype, congenital coagulopathies and thrombocytopathies, hemophilia, isolated vascular pathologies, as well as other types of Ehlers-Danlos syndrome and identified dEDS in the patient only clinically. Genetic testing did not reveal any pathological mutations or exonic deletions/duplications. The negative result of genetic testing in dEDS is due to the fact that certain types of mutations (e.g., deep intronic mutations) cannot always be detec­ted by standard diagnostic genetic methods. Conclusions. It is possible to establish a diagnosis based on clinical symptoms, but an extended mutation search is mandatory for the entire family.
IOF-ESCEO World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases — 2023: the Ukrainian Association of Osteoporosis participation
Authors: Kuprinenko N.V.
Published: October 2023

No abstract
Barriers Associated with Cardiovascular Disease and the Impact of Primary Care Leading to Necessary Emergency Department Visits in The Central Valley
Authors: Garcia Tanisha Dennelle , Alcala Emanuel , Purewal Shareen , Garispe Ashley , Helm Travis
Published: October 2023

Purpose: The research identified barriers associated with cardiovascular disease and the impact of primary care leading to emergency department (ED) visits in the Central Valley. Methods: A semi-structured 16-question interview was conducted at St. Agnes Medical Center in order to gain a fuller understanding of the involvement of primary care providers and their interactions in educating individuals about CVD. Results: 54 of the total 63 participants report having access to primary care however, some patients expressed they never had access to a cardiologist. Many of the participants (41 of 63) were confident that their care providers were greatly knowledgeable. A total of 46 of the 63 participants felt adequately cared for, while eight of the participants felt that the care, they received was not adequate by reporting that the care was bad or inadequate. Participants expressed that there were some challenges in receiving accessibility of care and many faced socioeconomic challenges. Conclusion: There have been many studies focusing on readmission rates with the expansion of ACA. However, none specifically evaluates a region within a state that has multiple socio-economic challenges and the use of primary care visits in relation to cardiovascular disease emergency department visits. There are many socioeconomic factors that, when not favorable, can lead to inadequate care towards the patient. Therefore, strategies to improve the care provided to diagnosed patients should be informed and guided by the influence that these socio-economic factors have with regard to the healthcare experience.
Hacia una historia epistemológica de la Química Organometálica: interpretación filosófica desde Larry Laudan (I)
Authors: Cárdenas-Acero Alexander , Mosquera Suárez Carlos Javier , Baquero Velasco Edwin Arley
Published: October 2023

Diversos autores han demostrado que un enfoque histórico de la enseñanza de la química puede ser complementado desde una visión de la filosofía de la ciencia. Esto permite abrir el panorama de comprensión de lo que implica hacer química y abordar así aspectos de esta disciplina como una empresa dinámica en constante cambio y evolución. En tal sentido, este artículo persigue hacer una interpretación filosófica de la historia de la Química Organometálica desde las posturas de Larry Laudan. Para lograr este objetivo, se realiza un análisis de los modelos clásicos de cambio científico (Kuhn, Lakatos) como antecedentes del modelo de Tradiciones de Investigación (TI) de Laudan. Una vez expuestas las generalidades de dicho modelo, se presenta la definición formal de la Teoría de Coordinación como una TI que orienta la disciplina objeto del estudio; de tal manera que se hace posible el desarrollo de un análisis a nivel macro-teórico, en términos de Laudan, de dicha tradición. Finalmente, se presentan algunos comentarios a manera de conclusiones y perspectivas para futuras reflexiones.
IOT Based Fruits Spoilage Detection using IOT
Authors: D Mr. Prakyath
Published: October 2023

Abstract: In the modern era of technology and with increasing dependency on smart techniques like mobile phone, there is requirement of solving daily life tasks in a quick and easy ways. This project is based on food detection system using Arduino. The microcontroller panel has the capability to perform functions which include interpreting inputs and outputs and make the sensor to activate.
IOT Based Smart Fire Detection and Control System using GSM Module
Authors: Chinchmalatpure Sheela , Sagar Anurag , Lohe Rounak
Published: October 2023

Abstract: In recent years, there has been a significant increase in the number of fire accidents reported worldwide. To mitigate the loss caused by fire accidents, we have proposed a new system for fire detection and control using the Internet of Things (IoT) and GSM. The proposed system consists of multiple sensors that are placed in various locations of a building to detect the occurrence of a fire. When a fire is detected, the system sends an alert to a remote location through GSM. Additionally, the system is also capable of controlling the spread of fire by activating a sprinkler system. This paper discusses the design, implementation, and testing of the proposed system.
The Impact of Yoga on School Children: A Thematic Review
Authors: Tiwari Apurva
Published: October 2023

Abstract: Introduction- In the fast-moving world, there is less importance given in society to health issues. Everyone has a dream of disease-free life to spread happiness in their personal and professional life. Today, many health problems are emerging, especially in children, impacting their growth and development. Purpose-The purpose of the paper is to study the significance of Yoga practice in school-going children on different parameters of health like physical health, physiological health, and psychological health. Methodology- The paper is a thematic paper based on the practical experience of Yoga. This includes an overview of the basic concepts of Yoga scriptures in the light of holistic health. Findings- Regular practice of Yoga makes Children an essential tool for creating awareness of knowledge of the laws of Nature which will help them to turn out more efficient and solid within a short span of time
Sociology of the body as an independent research direction: prerequisites for formation and subject field
Authors: Starostina D. A.
Published: October 2023

In the contemporary society, under globalization, digitalization, urbanization and networkization, the body acquires new meanings, is included in new discourses and becomes a significant object of sociology. The article considers the possibility of sociology of the body as an independent scientific direction similar to such directions as sociology of medicine, sociology of sexuality, feminist sociology, sociology of sports, sociology of food and nutrition, sociology of aging, etc. The problem of the body has a long tradition of scientific research, and the author identifies the prerequisites for sociology of the body in various areas of social knowledge: philosophy, anthropology, psychology, and general sociology. The author describes four basic research fields in sociology of the body: body as an object of social control; issues of sex and gender; body as an object of consumption; body and technology - development of biotechnology and selftracking technologies. These thematic blocks of sociology of the body are not isolated from such related fields as sociology of medicine, sociology of sexuality, feminist sociology, etc. All directions in the sociological study of the body are interrelated; however, each of them, including sociology of the body, has its own research field. Thus, sociology of the body studies the body in all its diverse social manifestations; the body as an element of social structure and social action; mutual influence of the body and contemporary transformations, such as urbanization, globalization, digitalization, networkization, etc.; emerging social movements focusing on the construction of identity and of the individual corporal project. The body becomes a project that can/should be improved and promoted. The “formed” body reflects such life attitudes of the individual as a sense of style and taste, attitudes to health, self-control, etc. Thus, through the body, the individual creates one’s social representation and identity: the image of “I”.
Russia and Mongolia in the civilizational and geopolitical paradigms of Central Eurasia development
Authors: Zheleznyakov A. S. , Chuluunbaatar G.
Published: October 2023

The relationship between Russia and Mongolia in the civilizational and geo-political paradigms of Central Eurasia development is extremely important for political science, sociology and regional studies. The authors’ definition of Central Eurasia differs from the generally accepted neutral interpretation due to its connection with a specific civilizational space - three local civilizations - the historically summarized limits of their dominant influence. The article considers the following limits of the influence of the Mongolian, Russian and Chinese civilizations from ancient times to the present: the great steppe empires (from the state of the Xiongnu to the Great Mongol Empire of Genghis Khan) with the center in Mongolia, the Russian Empire and the socialist camp with the center in Russia (USSR), and the economic corridor Russia-Mongolia-China with centers in three countries. The recognition of the taxonomic equilibrium of Russia, China and Mongolia as the cores of the Russian, Chinese and Mongolian civilizations, united by the space of Central Eurasia, allows to reconsider the Russian-Mongolian relations from ancient times to the present. The authors admit the existence of the world civilization hidden in Inner Asia and based on more than two thousand years of the nomads’ written history - the Mongolian civilization. The authors develop a new scientific direction - civilizational political science which considers the interaction between societies through the intertwined civilizational world order. The authors believe that civilizations cover the entire global space; introduce the concept “cascade of the civilizational boundaries”, which requires a combination of modeling methods and geoinformation technologies with cultural-historical ideas; consider the historical tradition of relations between Russia, Mongolia and China in the Eurasian region as being revived in the new context of trilateral cooperation.
The latest forms and models of the cooperative movement
Authors: Ovchintseva L. A.
Published: October 2023

On June 30, 2023, the third international scientific-practical conference “The latest cooperation in agriculture: Alternative forms and models in support of the economic theory of I.V. Emelyanov” was organized on the initiative of a team of scientists - specialists in the field of rural cooperation. Presentations were made by both theoreticians and practitioners of rural cooperation, who focused on the contradictions in the development of the cooperative movement and discussed new models and forms of cooperation in the theoretical and practical perspectives.
PERBANDINGAN DAYA HAMBAT MINYAK ATSIRI GREEN TEA DAN TEA TREE TERHADAP BAKTERI Staphylococcus Aureus
Authors: Fredella Dea Manda , Rahman Ave Olivia , Miftahurrahmah Miftahurrahmah
Published: October 2023

ABSTRACT

Background: Infectious diseases are a problem that is still a global concern. Staphylococcus aureus is a bacterium that is the most common cause of infection in the world. Treatment of infectious diseases is generally with antibiotics. One of the antibiotics that can be used to treat Staphylococcus aureus bacterial infection is chloramphenicol. An alternative that can be developed to reduce the problem of Staphylococcus aureus infection and resistance to antibiotics is the use of herbal plants or medicinal plants. The herbal plants that can be used are green tea leaf essential oil and tea tree essential oil. Methods: The type of research used is True Experimental with Posttest Only With Control Group Design. In this study, the materials to be tested were green tea essential oil and tea tree essential oil against Staphylococcus aureus bacteria with chloramphenicol as a positive control and aquadest as a negative control. Results: The average diameter of the inhibition zone on green tea essential oil was 11.45 mm, tea tree essential oil was 16.22 mm, positive control was 25.58 mm, while the negative control had no inhibition zone. and Green tea and tea tree essential oils are positive for alkaloids, tannins and terpenoids.Conclusions: There is a difference in the inhibitory power of green tea essential oil with tea tree.

Keywords: Essential Oil, Green Tea, Tea Tree, Bacteria

 

ABSTRAK

Latar Belakang: Penyakit infeksi merupakan masalah yang masih menjadi perhatian dunia. Bakteri Staphylococcus aureus adalah bakteri yang merupakan penyebab infeksi tersering didunia. Pengobatan penyakit infeksi umumnya dengan pemberian antibiotik. Salah satu antibiotik yang dapat digunakan dalam mengobati infeksi bakteri Staphylococcus aureus adalah kloramfenikol. Alternatif yang dapat dikembangkan untuk mengurangi permasalahan infeksi bakteri Staphylococcus aureus dan resisten terhadap antibiotik adalah penggunaan tanaman herbal atau tanaman obat. Adapun tanaman herbal yang dapat digunakan adalah minyak atsiri daun teh hijau (green tea)  dan minyak atsiri tea tree. Metode: Jenis penelitian yang digunakan adalah True Eksperimental dengan Posttest Only With Control Group Design. Pada penelitian ini bahan yang akan diuji adalah minyak atsiri green tea  dan minyak atsiri tea tree terhadap bakteri Staphylococcus aureus dengan antibiotik kloramfenikol sebagai kontrol positif dan aquadest sebagai kontrol negatif. Hasil: Diperoleh rerata diameter zona hambat pada minyak atsiri green tea sebesar 11,45 mm, pada minyak atsiri tea tree sebesar 16,22 mm, kontrol positif sebesar 25,58 mm, sedangkan kontrol negatif tidak memiliki zona hambat dan Minyak atsiri Green tea  dan tea tree positif mengandung senyawa alkaloid, tanin dan terpenoid. Kesimpulan: Terdapat perbedaan daya hambat minyak atsiri green tea dengan tea tree.

Kata Kunci: Minyak Atsiri, Green Tea, Tea Tree, Bakteri
Inovasi Media Pembelajaran MPASI pada Blok Elektif Gizi Klinik
Authors: Suzan Raihanah , Halim Rita , Ayudia Esa Indah , Miftahurrahmah Miftahurrahmah
Published: October 2023

ABSTRACT

Background: Since the Covid-19 pandemic took place worldwide, distance learning has replaced traditional face-to-face learning in the classroom. Therefore, it is necessary to innovate learning media that can support the student learning process. The learning media innovation carried out in this study was making a video on the practice of making MPASI. Methods: Evaluation of learning media using a questionnaire given to media experts, material experts, and users (students). Results: There were two media experts, two material experts, and 35 users (students) who were respondents to this study. All media experts agree that learning media can be used, but one media expert still suggests revisions for the future. All material experts agree that learning media can be used without revision. All users (students) agree that learning media can be used, but 12 users (34.3%) suggest revisions to learning media for the future. Conclusion: The current learning media can be used, but it still requires a slight improvement in the future.

Keywords: Learning media innovation, MPASI, Covid-19

 

ABSTRAK

Latar belakang: Sejak terjadinya pandemi covid-19 yang berlangsung diseluruh dunia, pembelajaran jarak jauh telah menggantikan pembelajaran tatap muka tradional di dalam kelas. Oleh karenanya diperlukan inovasi media pembelajaran yang dapat menunjang proses pembelajaran mahasiswa. Inovasi media pembelajaran yang dilakukan pada penelitian ini adalah pembuatan video praktek pembuatan MPASI. Metode: Untuk mengevaluasi media pembelajaran digunakan kuesioner yang diberikan kepada ahli media, ahli materi dan pengguna (mahasiswa). Hasil: Terdapat 2 orang ahli media, 2 orang ahli materi dan 35 orang pengguna (mahasiswa) yang menjadi responden dalam penelitian ini. Semua ahli media setuju bahwa media pembelajaran sudah dapat digunakan, namun salah satu ahli media masih menyarankan adanya revisi untuk kedepannya. Semua ahli materi telah setuju bahwa media pembelajaran sudah dapat digunakan tanpa revisi. Semua pengguna (mahasiswa) setuju bahwa media pembelajaran sudah dapat digunakan, namun terdapat 12 orang (34,3%) pengguna (mahasiswa) yang menyarankan adanya revisi media pembelajaran untuk kedepannya. Kesimpulan: Media pembelajaran saat ini telah dapat dipergunakan, namun masih memerlukan sedikit perbaikan untuk kedepannya.

Kata Kunci: Inovasi media pembelajaran, MPASI, Covid-19
3D Model Backprojection of the 2017 Mw 8.2 Chiapas Earthquake: A Two-Stage Rupture with a Barrier-Induced Velocity Increase
Authors: Song Chao , Ge Zengxi
Published: October 2023

We carry out a backprojection analysis of high-frequency P-wave signals
to image the rupture process of the 8 September 2017 Mw 8.2 Chiapas
earthquake based on the 3D velocity model LLNL-G3Dv3. Results show that
the entire ∼56 s unilateral rupture process clearly involves two stages.
The first stage lasted for ∼37 s, with a northwest (∼322° azi- muth)
propagation over a length of ∼89 km at a speed of ∼2:8 km=s. Then, the
rupture made a right turn within a short distance and propagated to
∼348° azimuth for ∼74 km at a higher speed of ∼4:6 km=s. The two-stage
rupture was further confirmed by the power release, data coherency,
beamforming patterns, and aftershock distribution. The overall rupture
can be well explained by a two-fault model. Rupture on the second fault
was positively triggered by that on the first one. The Tehuantepec
Fracture Zone, which transversely intersects the Middle American trench
as well as the coseismic rupture zone, likely functioned as a barrier to
the first stage. Upon reaching the barrier, the rupture was temporarily
blocked and deceler- ated, but eventually detoured to cross the barrier
with the aid of the accumulated stress. The abrupt release of stress led
to a much higher rupture speed in the second stage.
Projecting Future Chronic Coastal Hazard Impacts, Hotspots, and Uncertainty at Regional Scale
Authors: Leung Meredith C , Cagigal Laura , Méndez Fernando J. , Ruggiero Peter
Published: October 2023

While there is high certainty that chronic coastal hazards like flooding
and erosion, are increasing due to climate change induced sea-level
rise, there is high uncertainty surrounding the timing, intensity, and
location of future hazard impacts. Assessments that quantify these
aspects of future hazards are critical for adaptation planning under a
changing climate and can reveal new insights into the drivers of coastal
hazards. In particular, probabilistic simulations of future hazard
impacts can improve these assessments by explicitly quantifying
uncertainty and by better simulating dependence structures between the
complex multivariate drivers of hazards. In this study, a regional-scale
probabilistic assessment of climate change induced coastal hazards is
conducted for the Cascadia region, USA during the 21st century. Three
co-produced hazard proxies for beach safety, erosion, and flooding are
quantified to identify areas of high hazard impacts and determine hazard
uncertainty under three sea-level rise scenarios. A novel chronic
coastal hazard hotspot indicator is introduced that identifies areas
that may experience significant increases in hazard impacts compared to
present day conditions. We find that Southern Cascadia and Northern
Washington have larger hazard impacts and hazard uncertainty due to
their morphologic setting. Erosional hazards, relative to beach safety
and coastal flooding, will increase the most in Cascadia during the 21st
century under all sea-level rise scenarios. Finally, we find that hazard
uncertainty associated with wave and water level variability exceeds the
uncertainty associated with sea-level-rise until the end of the century.
Thermal recovery test for determining the thermal conductivity of the soil
Authors: Vasilev Marija , Banjac Milos
Published: October 2023

This paper presents a new in-situ experimental procedure for determining a thermal conductivity of soil, as one of the thermophysical properties necessary for dimensioning vertical buried heat exchangers of geothermal heat pumps. The proposed method, called the thermal recovery test, is based on the assumption that there is a direct analogy between the hydrodynamic process of filling (recovery) the well with water from a porous aquifer after its partial or complete discharging and the process of establishment of thermal equilibrium in an infinite medium previously disturbed by a line heat sink (source). Apart from presentation the theoretical background of these two phenomena, the display of the identical theoretical logarithmic character of the change of hydrostatic pressure and soil temperature, description of the experimental procedure, the experimental results of three performed experiments are also presented. Additionally, results for the experimentally obtained values of the thermal conductivity of the soil are compared with those obtained from the thermal response test, and the advantages and drawbacks of the new thermal recovery test method are analyzed.
Drying Of Kanlıca Mushroom By The Hot Air Drying Method And The Investigations Of Its Effects On Its Quality
Authors: Kayataş Ongun Göknur , Aktaş Mustafa , Acar Bahadir , Özkaymak Mehmet
Published: October 2023

In this study done, by providing the hot air drying of Kanlıca mushroom collected from Karabuk city; prevention of aflatoxin occurrence, shelf life extension, taking precaution against early putrefaction and decomposition, protection of the beneficent aromas in its content have been ensured. As the dried product, Kanlıca mushroom, the most consumed endemic plant spicy in terms of the vitamin and the mineral that it contains among the mushroom groups, has been used. By means of hot air drying, drying has been done at five different (30oC, 40oC, 50oC, 60oC and 70oC) temperatures. The best result in terms of water activity, colour changes, energy consumption and drying duration has been obtained in the experiments at 50oC. The water activity values of products (fresh mushroom water activity: 0,983 aw) dried in hot air drying processes have been found in 0,429 and 0,173 interval (in literature lower than 0,6) and according to the colour analysis experiments result, L*, a*, b*, C*, Ho, ∆E, BI values of Kanlıca mushroom dried at different temperatures have been calculated. According to the result of the analyses, it has been detected that the preservation of mushrooms by freezing and hot air drying is appropriate.
Activities of daily living in lower limb amputees with a bone-anchored prosthesis: a retrospective case series with 24 months’ follow-up
Authors: Saleib Michael-Kyrillos M , Van Lieshout Esther M M , Verduin Dorien , De Graaff Heleen P , Paping Maria A , Verhofstad Michael H J , Van Waes Oscar J F
Published: October 2023

Background and purpose: Little is known about the activities of daily living (ADL) of patients with a bone-anchored prosthesis (BAP). We aimed to objectively measure ADL without and with BAP during standard care of follow-up. Our secondary aim was to measure mobility and walking ability.Patients and methods: Patients aged 18–99 years who underwent surgery for transfemoral or transtibial BAP between September 11, 2017, and February 11, 2021, were eligible for inclusion in this retrospective case series of patients with socket prosthesis. ADL was measured with a continuous recording activity monitor (hours [h]) before surgery, and at 6, 12, and 24 months with BAP. Mobility and walking ability were assessed by the Timed Up and Go test (TUG) (seconds [s]) and 6 Minute Walk Test (6MWT) (meters [m]), respectively.Results: 48 of the 57 eligible patients provided informed consent and were included. Their age was 59 (1st quartile to 3rd quartile 51–63) years. Total daily activity before BAP was 1.6 h (0.82–2.1) and increased to 2.1 h (1.4–2.5) at 6, 2.0 h (1.5–2.7) at 12, and 2.7 h (2.0–3.3) at 24 months with BAP. Daily walking increased from 1.3 h (0.79–1.9) before BAP to 1.8 h (1.6–2.3) at 6, to 1.7 h (1.2–2.4) at 12, and 2.0 h (1.6–2.6) at 24 months. Median TUG decreased from 12 s (9.1–14) before BAP to 8.9 s (7.7–10) at 24 months. Mean 6MWT increased from 272 m (SD 92) before BAP to 348 m (SD 68) at 24 months.Conclusion: Objective measurements on ADL positively changed in patients with BAP. This effect was also seen in mobility and walking ability at 24 months.
Transspinal direct current stimulation with an intensity of 2.5 mA does not affect the corticospinal system excitability and motor skills
Authors: Pomelova Ekaterina D. , Popyvanova Alyona V. , Bredikhin Dmitry O. , Koriakina Maria M. , Shestakova Anna N. , Blagovechtchenski Evgeny D.
Published: October 2023

BACKGROUND: Noninvasive brain stimulation effectively affects movements, including the spinal cord level. Stimulation effects are very sensitive to montage and protocols of applied stimulation because they can involve different neuronal mechanisms.
AIM: This study aimed to estimate the effect of anodal transspinal direct current stimulation (tsDCS) with an intensity of 2.5 mA applied at the spinal cord level (C7–Th1 segments) with cervical enlargement on the corticospinal system excitability and motor skills.
METHODS: The study involved 54 healthy adults aged 21.19±3.20 years. The effect of tsDCS was assessed using motorevoked potentials from the first dorsal interosseous (FDI) muscle by transcranial magnetic stimulation in the primary motor cortex before stimulation, immediately after stimulation, and after 15 min.
RESULTS: The application of an 11-min anodal tsDCS with a current value of 2.5 mA at the C7–Th1 level did not affect the motorevoked potentials of FDI. Statistically, changes in motorevoked potentials amplitudes did not differ between groups receiving anodal tsDCS and sham stimulation. In addition, anodal tsDCS did not affect motor skills. An individual’s ability to coordinate fingers and manipulate objects effectively (a measure of dexterity) in the nine-hole peg test and pressing a key in response to a visual stimulus in the serial reaction time task did not differ from that with sham stimulation.
CONCLUSION: 2.5 mA anodal tsDCS on cervical enlargement does not affect the corticospinal system excitability or change motor skills associated with precise hand movements.
Attitude to the disease in boys and girls with different gender identities
Authors: Ельникова Оксана Евгеньевна , Колосова Ирина Геннадьевна
Published: October 2023

Рассматривается вопрос о влиянии психологической характеристики «гендерная принадлежность» на отношение к болезни представителей современной молодежи. Представлены результаты диагностического исследования взаимосвязи гендерной идентичности и типов отношения к болезни. Дана характеристика понятию «болезнь» и анализ двум основным моделям возникновения и протекания болезни: биомедицинской и биопсихосоциальной. Проанализированы исследования особенностей реагирования на потерю здоровья носителей того или иного гендера. Отмечено, что гендерные особенности отношения к болезни могут стать важным фактором общего улучшения ситуации и в сфере здравоохранения, и в повседневной жизни носителей разных гендерных ролей, общего повышения уровня и качества жизни населения. Представленные данные позволяют заключить, что учет поведенческих реакций, индивидуально-типологических характеристик человека позволит избежать нарастания симптомов, порожденных самой стрессогенной ситуацией – болезнью. Полученные результаты доказывают, что модель поведения и индивидуальные реакции людей зачастую обусловлены гендерной принадлежностью, которая в современных реалиях не всегда совпадает с половой.

The question of the influence of the psychological characteristic gender identity on the attitude of representatives of modern youth to the disease is considered. The results of a diagnostic study of the relationship between gender identity and types of attitude to the disease are presented. The characteristic of the concept of “disease” is given, the analysis of two main models of the occurrence and course of the disease is given: biomedical and biopsychosocial. Studies of the peculiarities of responding to the loss of health of carriers of a particular gender are analyzed. It is noted that gender-specific attitudes to the disease can become an important factor in the overall improvement of the situation in the healthcare sector and in the daily life of carriers of different gender roles, the overall improvement of the level and quality of life of the population. The data presented in this article allow us to conclude that taking into account behavioral reactions, individual typological characteristics of a person will help to avoid an increase in symptoms generated by the most stressful situation – the disease. The results obtained prove that the behavior model and individual reactions of people are often determined by gender, which in modern realities does not always coincide with gender.
Antonio Scarpa. Scientist's contribution to the history of medical art
Authors: Kryvetskyi V.V. , Kuz`mak O.O. , Proniaiev D.V. , Kavun M.P.
Published: October 2023

The contribution of Italians to the medical field cannot be denied, yet, despite their discoveries and outstanding work with their results and impact, many Italian scientists still need to be remembered or known by the average physician or student and the non-medical person. The Italian scientist Antonio Scarpa significantly contributed to the development of medicine. Still, his contribution remains forgotten by many doctors and scientists, but until now, his contribution remains overlooked by many doctors and scientists, and only a few people know about the existence of such a scientist and his works. Scarpa's first discovery that made him famous was far from the femoral triangle. In his studies, Antonio Scarpa was the first to describe the membranous labyrinth of the ear and the vestibular ganglion. He published his first work "Anatomical observations on the structure of the round window of the ear, or the secondary tympanic membrane." Scarpa began researching the nervous system and published his observations on the anatomy of the ganglia and plexuses in 1779, a forerunner of his most important work, a neurological atlas published in 1794. In addition to all his skills, Antonio Scarpa was also a talented artist. All the drawings in his works were made by him personally. He later passed on this skill, and this part of the work, to his student Faustino Anderloni. All of Scarpa's discoveries were illustrated by him and his student, and in anatomy there are many eponyms associated with the name of Antonio Scarpa: Scarpa's triangle, Scarpa's fascia, Scarpa's fluid, Scarpa's nerve and Scarpa's sheath. It is simply impossible to overestimate Antonio Scarpa's contribution to medicine, just as it is impossible to estimate the scale of the scientist's mark on the pages of history. Scarpa's discoveries became the starting point for hundreds of other studies and works, and his works became educational aids for future doctors and scientists decades after their publication and even after Scarpa's death.