bluuebunny/crossref_metadata_2025 huggingface dataset:
Vermikompost Uygulamalarının San Andreas (Fragaria x ananassa Duch.) Çilek Çeşidinin Bazı Verim ve Kalite Değerlerine Etkisi
Authors: Develi Erdem Asaf , Yavuz Ayşegül , Erdoğan Ümmügülsüm
Published: January 2022

In this study, in which the effects of different applications of vermicompost on the yield and quality of San Andreas strawberry variety were investigated 15, 30, 45, 60 g vermicompost was applied per plant. First flowering, first and last harvest dates, number of fruits per plant, yield per plant (g/plant), fruit weight (g), fruit flavor, macro and micro nutrient content, organic acid amounts were examined. The results showed that the differences between treatments in yield per plant were statistically significant. The highest total yield per plant was obtained from V45 and V30 applications with 972.8 g and 878.9 g respectively and the lowest yield was obtained from the control application with 384.2 g per plant. The largest fruits were obtained from the V60 (19.5 g) application. It was determined that nitrogen, phosphorus, potassium, magnesium, sulfur, manganese, iron, zinc and boron concentrations in the leaves of strawberry plants fertilized with vermicompost were higher than the control. The highest values in organic acid values were determined in oxalic, propionic, malonic, lactic, fumaric and succinic acids in V60 application (5.62, 11.16, 49.00, 104.98 µg/100 g respectively). It seems that the application of vermicompost fertilizer in strawberry cultivation has a positive effect on yield and quality characteristics.
Evaluation Data of Dried Vegetables and Fruits
Authors: Çağlarırmak Necla , Hepçimen Ahmet Zeki
Published: January 2022

Drying is the process of removing of the water that has destroying effect in food products by evaporation and. Research project on the basis of direct sun drying and solar greenhouse. Basic operations research in food engineering, food chemistry, food quality control and toxicology has been established over such a broad spectrum. Subjects of investigation were in accordance with all of the values of dry matter basis. The study of dry matter and water activity values of each product (aw), direct sun drying, drying in the greenhouse. It was determined comparing nutrients of samples those were applied directly to the greenhouse and drying in the sun. Sampling patterns of research were explained as follow; tomatoes drying in the sun (external environment), and greenhouse, bell peppers in the greenhouse and drying in the sun, soaked raisins (sultanas) and not-soaked (raisin), sun-dried, sun-dried fig products directly. Nutrients of the samples such as; lycopene, thiamine (B1), riboflavin (B2), retinol (A), Pyridoxine (B6), ascorbic acid (C), folic acid, magnesium (Mg), potassium (K), sodium (Na), phosphorus (P), zinc (Zn), iron (Fe), copper (Cu) were quantitatively determined. The red pepper products, dried figs and dried grapes mycotoxin amounts were in safe levels, which had not created any hazard and risk for health. Red pepper and dried figs, total aflatoxins, (B1, B2, G1, G2), ochratoxin A (OTA) levels in raisin in the European Union is set well below the limits in terms of human health hazard and the risk factor has been identified.
Humik Asit Uygulamalarının Zambak Bitkisinin Gelişimi, Bitkideki Fenolojik ve Pomolojik Gözlemler Üzerine Etkisi
Authors: Ataklı Seda Bice , Şahin Sezer , Alkaç Onur Sefa
Published: January 2022

In this study, a pot study was carried out to reveal the effects of direct and foliar applications of humic acid to the growing medium in addition to basic fertilization on the development and plant quality characteristics of lily plants grown in peat + perlite medium. The experiment was carried out in an unheated greenhouse during the summer, in a greenhouse environment with a shade net on it. In the experiment, in addition to the control, the humic acid doses were 3.5 lt/da from soil, 7.5 lt/da from soil, 1.75 lt/da from leaf, 3.75 lt/da from leaf and soil + 3.5 lt/da from leaf + 1, It was applied 3 times as 75 lt/da. In the pot experiment established in three replications according to the randomized plots trial design, 10 lily bulbs were planted in each pot and humic acid applications were made at two-week intervals following plant emergence. In order to see the effect of the applications when the plant is harvested, the length of the flower stem (mm), the thickness of the flower stem (mm), the fresh weight of the branch (mm), the number of buds (pieces), the bud length (cm), the number of leaves (pieces), Full bloom stem (mm) and vase life (days) were examined. As the doses of humic acid increased, the vegetative weight of the lily plant increased, while the effect of the applications on the investigated properties was different. With the mineral elements, hormones and plant growth regulators in humic acid, it has the feature of promoting the increase of biomass in the plant.
Allergic reactions during childhood vaccination and management
Authors: Aytekin Elif Soyak , Şekerel Bülent E , Şahiner Ümit M
Published: January 2022

Background. Vaccination is one of the most effective public health tools to prevent a variety of infectious diseases. However, concerns about vaccine related adverse effects cause difficulties in clinical practice.
Methods. This review was prepared based on the latest literature available in the PUBMED database in English language (as of March 2021), and all articles with the keywords pediatric vaccine, allergy, hypersensitivity, adverse reaction were evaluated to prepare the article.
Results. Vaccine related confirmed allergic reactions are rare in children, ranging between 0,65-1.45 cases per million vaccine doses. Most of the allergic reactions are self-limited local reactions although in some cases severe anaphylaxis with multisystem involvement can be observed. Allergic reactions may occur because of either the active component (the antigen) of the vaccine, or additional components, such as preservatives, adjuvants, antimicrobials, stabilizers and other substances. Finding the culprit allergen is necessary to prevent future exposure to the allergen and to use alternative vaccines if possible. Diagnosis is largely based on a detailed history and clinical manifestation; also in vivo and in vitro tests may be helpful.
Conclusions. In this review we provide information about hypersensitivity reactions to allergen components of childhood vaccines along with the diagnosis and management of vaccine allergy. Besides the tremendous benefits of vaccination for the health of children, we emphasized that the risk of adverse effects is rare and poses a negligible threat.
Clinical characteristics, late effects and outcomes in pineoblastomas in children: a single center experience
Authors: Görgün Ömer , Koç Başak , Kebudi Rejin , Wolff Johannes E , Kebudi Abut , Darendeliler Emin
Published: January 2022

Background. Pineoblastomas (PB) are rare tumors of the central nervous system and are more common in children. There is no consensus about standard of care. The objective of this study is to analyze the outcome of children with PB.
Methods. Six patients with PB who were diagnosed between 1990-2012 were evaluated retrospectively. Demographics, age of diagnosis, first complaint, tumor region, diagnosis type, seeding metastasis to the spinal axis or cerebrospinal fluid (CSF), treatment and survival of these patients were recorded.
Results. Three patients had subtotal resection and all patients received chemotherapy and craniospinal irradiation (CSI) after diagnosis. Median follow-up after treatment was 5.5 (range:1-19) years. Two patients are alive with no evidence of disease for 7.5 and 10 years, one of whom was diagnosed with papillary thyroid carcinoma 9.5 years after treatment. One of the patients who died had lived for 19 years after diagnosis.
Conclusions. Pineoblastomas are rare but very aggressive tumors; more effective treatment strategies are needed. Survivors should be followed up for late effects such as second malignancies and endocrine deficiencies.
Thiol / disulfide balance and oxidative stress parameters in pediatric patients diagnosed with acute and chronic idiopathic thrombocytopenic purpura
Authors: Kar Yeter Düzenli , Özdemir Zeynep Canan , Bör Özcan
Published: January 2022

Background. Changes in oxidative stress and thiol / disulfide balance are thought to play a role in the pathogenesis of idiopathic thrombocytopenic purpura (ITP). Our study investigates total oxidant level (TOS), total antioxidant level (TAS), oxidative stress index (OSI) levels and thiol / disulfide balance in pediatric patients with acute and chronic ITP.
Methods. Thirty four patients with acute ITP, eighteen patients with chronic ITP and thirty three healthy children (control) were included. TOS, TAS, OSI, thiol / disulfide balance were analyzed.
Results. In acute ITP, TAS levels were lower than chronic ITP and control, TOS and OSI levels were higher than control, and native thiol level was lower than chronic ITP (p < 0.05). In acute ITP; disulfide level, disulfide / native thiol and disulfide / total thiol ratios were higher than chronic ITP and control, and native thiol / total thiol ratio was lower than chronic ITP and control group (p = 0.038, p = 0.018, respectively). TOS and OSI levels of the chronic ITP were higher than the control group (p < 0.05).
Conclusions. The results of this study have shown that oxidative stress increases in children with acute ITP and chronic ITP, that thiol / disulfide balance is disrupted in favor of disulfide in acute ITP, and that thiol / disulfide balance isn`t disrupted in chronic ITP patients whose platelet count is close to normal and who don`t require treatment.
Tuberculosis risk in the biologic era: tuberculin skin test conversion rates in children with rheumatologic diseases
Authors: Özlü Canan , Türkuçar Serkan , Asrak Hatice Karaoğlu , Dündar Hatice Adıgüzel , Ünsal Şevket Erbil , Belet Nurşen
Published: January 2022

Background. The widespread use of biological treatments has increased the frequency of opportunistic infections such as tuberculosis (TB). The primary objective of our study was to determine the rate of tuberculin skin test (TST) conversion during biological therapy. The secondary objective was to monitor the side effects related to isoniazid (INH) prophylaxis, in the selected subgroup.
Methods. Children with rheumatologic diseases receiving treatment with tumor necrosis factor-alpha (TNF-α) inhibitors, and tocilizumab and canakinumab were included in the study. If baseline screening was negative, TST was performed annually after initiation of biologic therapy. TST conversion was accepted as an increase of at least 6 mm and becoming positive or an increase of 10 mm or more, even in the absence of positivity.
Results. 121 patients (female n: 63, 52%) were included in the study. The mean follow-up period was 26.10±14.8 months. 85 of the patients were using TNF-α inhibitors and 18 tocilizumab, and 18 canakinumab. Forty patients had positive TST before biological agents and received chemoprophylaxis with INH. The rate of TST conversion among the 3 biological agents was not statistically significant (20.4% of TNF-α inhibitors, 25% of canakinumab and 33.3% of tocilizumab users). All patients with LTBI received INH prophylaxis, and none of them had active TB.
Conclusions. There was no statistically significant difference among the three biological agents, regarding the seroconversion rates. Patients receiving tocilizumab and canakinumab should also be screened for TB during follow-up. INH related side effects are rare.
Could plasma based therapies still be considered in selected cases with atypical hemolytic uremic syndrome?
Authors: Özlü Sare Gülfem , Söylemezoğlu Oğuz , Topaloğlu Rezan , Özçakar Zeynep Birsin , Acar Banu , Taşdemir Mehmet , Çomak Elif , Özdoğan Elif Bahat , Parmaksız Gönül , Delibaş Ali , Atayar Emine , Aydoğ Özlem , Gülhan Bora , Özaltın Fatih
Published: January 2022

Background. Atypical hemolytic uremic syndrome (aHUS) occurs due to defective regulation of the alternative complement pathway (ACP) on vascular endothelial cells. Plasma based therapy (PT) was the mainstay of the treatment for aHUS for many years until the introduction of therapies targeting blockage of the complement system. The aim of this study was to evaluate patients with aHUS who had been treated with plasma based therapies alone.
Methods. The outcomes of seven genetically confirmed aHUS patients (2 girls, 5 males) were evaluated by means of clinical presentation, response to plasma therapy, course of the disease during the follow-up period and last status.
Results. The median age of the patients at admission was 6.7 years (IQR 0.7-7.8). Three patients received plasma exchange therapy and the other four patients were treated with plasma infusions. One patient was lost to follow-up after one year; the median duration of follow-up for other patients was 3.7 years (IQR 2.7-6.5). During the follow up, two patients from our historical records when complement blocking therapies had not been in clinical use yet in Turkey, underwent kidney transplantation. One transplant patient experienced an acute rejection episode without graft loss. The remaining five patients had a glomerular filtration rate of more than 90 ml/min./1.73 m < sup > 2 < /sup > at the last visit.
Conclusion. Although we had a relatively small patient population, our findings indicate that PT might still be considered in selected patients particularly in countries where complement blocking therapies are difficult to reach due to their unavailability or costs that are not covered by the health care systems.
Investigation of immunity against Bordetella pertussis in pregnant women and an overview of the vaccination schedule in Turkey
Authors: Gül Serdar , Sönmez Cemile , Ayvaz Gökçe , Kılıç Selçuk
Published: January 2022

Background. Pertussis caused by Bordetella pertussis, is a disease leading to significant morbidity and mortality in neonates and infants. Direct protection of the infant may be achieved by maternal and neonatal vaccination. Despite primary vaccination, infants under six months pose the greatest risk of infection with pertussis. Maternal immunization provides a high level of infant protection from birth until immunity is achieved by active vaccination. There is no routine Tdap vaccination recommendation for pregnant women in Turkey. This study was carried out to determine pertussis antibody levels in pregnant women and provide data for improving vaccine planning.
Methods. The study was carried out with 133 pregnant women in Turkey. Antibody titers to pertussis toxin (anti-PT) and filamentous hemagglutinin (anti-FHA) were measured by the commercially available ELISA.
Results. Among 133 participants, 93 (69.9%) were found to be immune according to anti-PT IgG antibody levels. According to anti-FHA IgG antibody levels, 123 (92.5%) participants were considered to be immune. A positive correlation was observed between PT and FHA and the findings were statistically significant (P < 0.001, r = 0.343). In the study group, the ages of the participants varied between 17 and 44 years. The mean age of those who were immune was 27.3±5.6, the mean age of non-immune patients was 29.1±6.2 and the difference was not statistically significant (P= 0.14).
Conclusions. Our results reveal that approximately one-third of pregnant women were not immune to pertussis, reflecting many young infants to be vulnerable to pertussis infection until the onset of primary vaccinations, although childhood pertussis vaccination coverage has been high for a long time. We conclude that Tdap vaccine recommendation for pregnant women regardless of previous immunization history may be beneficial for the protection of infants in their first six months.
Clinical follow-up of children with high vitamin B12 values: should we worry?
Authors: Albayrak Davut , Albayrak Canan
Published: January 2022

Background. Requests of Vitamin B12 test increased with the widespread use of autoanalysers. Although the cause of requests was deficiency suspicions, an important ratio of high levels of Vitamin B12 were reported to physicians by laboratory. Ratios of values of high Vitamin B12 among test request in adults are reported as 14- 20% in present three monocentre studies and one multicentre study. There is no report on children with high vitamin B12 for both ratio in lab requests or clinical follow up.
Methods. We evaluated the records of 40 children (23 male /17 female) with high B12 values ( > 1000 pg/ ml) retrospectively. Children were otherwise healthy children and were seen at outpatient pediatric clinics. Additionally, vitamin B12 values of 13 acute lymphoblastic leukemia patients at diagnosis time were retrieved to enlighten possible role of lymphocytes.
Result. Children did not have any malign or chronic diseases causing the high Vitamin B12 values. Holotranscobalamin levels were normal or slightly above. Two patients did develop leukemia later. Our follow up showed that high vitamin B12 values slightly decreased at 3 months and then remained unchanged later. The high numbers of T and B cells are not the source of vitamin B12 elevation.
Conclusions. Our study suggests that high-vitamin B12 values are usually benign in children but some patients may develop leukemia later. We suggest that patients should be followed up for some time after testing for severe hematological diseases.
On Estimating Reliability of a Stress – Strength Model in Case of Rayleigh Pareto Distribution
Authors: Haddad Emad Sh. M. , Batah Feras Sh. M.
Published: January 2022

The stress – strength model is one of the models that are used to compute reliability. In this paper, we derived mathematical formulas for the reliability of the stress – strength model that follows Rayleigh Pareto (Rayl. – Par) distribution. Here, the model has a single component, where strength Y is subjected to a stress X, represented by moment, reliability function, restricted behavior, and ordering statistics. Some estimation methods were used, which are the maximum likelihood, ordinary least squares, and two shrinkage methods, in addition to a newly suggested method for weighting the contraction. The performance of these estimates was studied empirically by using simulation experimentation that could give more varieties for different-sized samples for stress and strength. The most interesting finding indicates the superiority of the proposed shrinkage estimation method.
PRIMUM REMEDIUM ACTION SANCTIONS AGAINST CHILDREN IN CONFLICT WITH THE LAW
Authors: Anwar Mashuril
Published: January 2022

Criminal sanctions are more popular than action sanctions at the application level. Action sanctions formulation is regulated in Articles 82 and 83 of the Juvenile Criminal Justice System Law, while criminal sanctions are the last resort. However, criminal sanctions are still the "prima donna" in law enforcement practices against children in conflict. This condition raises various problems such as the overcapacity of correctional institutions, burdens the state budget, and creates a stigma against children in conflict with the law. Because the purpose of implementing the juvenile criminal justice system is in the child's best interests, action sanctions should be prioritised, even though criminal sanctions are needed in law enforcement against children in conflict with the law. Therefore, an idea emerged to restore criminal sanctions as ultimum remedium and strengthen action sanctions as primum remedium. The problem discussed in this study is how to implement primum remedium action sanctions against children in conflict with the law? And how to strengthen primum remedium action sanctions against children in conflict with the law? This study uses a normative juridical, an empirical juridical, and a comparative methods. The data in this article are sourced from primary and secondary data processed through description, prescription, and system. The results indicate that criminal sanctions still dominate judges' decisions in children in conflict with the law, and action sanctions are complementary sanctions because it is rarely applied.
THE BOARD OF DIRECTORS OF A BANKRUPT COMPANY’S CIVIL LIABILITY FOR OBTAINED TAXES
Authors: Nuki Nuki
Published: January 2022

Sumber Urip Sejati Utama Ltd. is a company that runs in the fertilizer industry. Technically, Sumber Urip Sejati Utama Ltd.'s board of directors purchase urea fertilizer for the factory, then sold the urea fertilizer to consumers. As a urea fertilizer distributor, Sumber Urip Sejati Utama Ltd. should fulfil tax administration obligations, such as reporting tax payments and calculations. However, Sumber Urip Sejati Ltd.’s administration is highly engineered by the company’s directors because Sumber Urip Sejati Utama Ltd. is operating even though it is declared bankrupt. The situation escalades when the company is faced with unfulfilled tax obligation. Therefore, the main problem in this research is the director board of Sumber Urip Sejati Utama's Ltd. civil liability and legal consequences towards the tax in debt due to the board’s negligence. The research method used in this study is a normative juridical approach, which is an approach based on the primary legal material by examining theories, concepts, legal principles and legislation. The research elaborates that the civil liability of Sumber Urip Sejati Utama Ltd.’s director board towards the tax in debts is in a form of joint responsibility or responsibility. Moreover, the legal consequences faced by the director boards due to their negligence is that directors should bear all of the company's debts to creditors and third parties, to the extent of using the directors' assets to cover the losses.
The Relevance of Supreme Court Regulation No. 1 of 2020 in Efforts of State Losses Refund through Restorative Justice
Authors: Kusuma Niko Jaya , Firganefi Firganefi , Farid Muhammad
Published: January 2022

The government has moved quickly to find a legal breakthrough related to reducing corruption in Indonesia. One of the efforts made by the government is through the Supreme Court to eradicate corruption is the enactment of Supreme Court Regulation No. 1 of 2020 concerning Guidelines for the Criminalization of Articles 2 and 3 of the Law on the Eradication of Corruption Crimes. The consideration is that the imposition of a crime must be carried out with due regard for the certainty and proportionality of punishment to realize justice based on Pancasila and the Republic of Indonesia's 1945 Constitution. The objectives of the Supreme Court Regulation prioritize victim’s losses to be recovered. Moreover, the regulation proportional benefits in imposing penalties on criminal cases is compatible with the Restorative Justice approach. The restorative justice process is expected to be a legal breakthrough in restoring state finances, with dealing with Criminal Corruption Cases focusing on efforts to restore state finances as a whole rather than just prosecuting the perpetrators. Thus, the purpose of this research is to determine how relevant Supreme Court Regulation No. 1 of 2020 are to efforts to recover state losses through restorative justice. This research employs both a normative and an empirical legal approach. Data were gathered through literature reviews and field studies and analyzed qualitatively. The present study confirmed the author's thoughts about the relevancies of Supreme Court Regulation No. 1 of 2020 to recover state losses through restorative justice as Supreme Court Regulation No. 1 of 2020 play a role as a law enforcement's main element as a legal substance.
THE EFFECT OF MODERATE LEADERSHIP BASED ON TRI KAYA PARISUDHA AND SOCIAL ATTITUDE ON EMPLOYEES’ PERFORMANCE
Authors: Suwindia I Gede , Wati Ni Nyoman Kurnia
Published: January 2022

This study aims to determine the effect of moderate leadership based on Tri Kaya Parisudha and social attitudes on employee’s performance at STAHN Mpu Kuturan Singaraja, both separately and together. This research is an ex-post facto research. The population in this study were all 77 employees of STAHN Mpu Kuturan Singaraja who were directly used as research samples. The independent variable in this study are moderate leadership based on Tri Kaya Parisudha and social attitudes, while the dependent variable is employees’ performance. The instrument used was a moderate leadership questionnaire based on Tri Kaya Parisudha, social attitudes, and employees’ performance. The data analysis method usedwais multiple regression and partial correlation techniques. The results showed that: 1) there was a significant effect of moderate leadership based on Tri Kaya Parisudha on employees’ performance, 2) there was a significant effect of social attitudes on employees’ performance, and 3) there was a significant effect of moderate leadership based on Tri Kaya Parisudha and social attitudes towards employees’ performance. 
PESAN MORAL DALAM CERITA UTTARAKĀNDA RAMĀYĀNA (Kajian dalam Perspektif Susila Pendidikan Agama Hindu)
Authors: Darma Permana I Dewa Gede
Published: January 2022

Abstract

Itihāsa is one part of the breadth of Vedic knowledge, which must be learned at the initial stage of learning Vedas. Speaking further about Itihāsa, Itihāsa consists of two great epic literature, namely Ramāyāna and Mahābhārata. So that the initial knowledge that one can learn when studying Itihāsa is the Ramāyāna book. The Ramāyāna book itself is generally composed of 7 parts known as the Sapta Kānda. Then in the resolution section there is the final Kānda section known as Uttarakānda and of course it contains a moral message. Reflecting on this, this research is interested in examining more deeply the story of Uttarakānda Ramāyāna, to find the moral message contained therein in the perspective of Susila's teachings. In this study, several problems were also formulated, namely related to the nature of the Sapta Kānda Ramāyāna, the Uttarakānda Ramāyāna story, and the moral messages contained therein. By using research methods with the type of qualitative research, and literature study and using data analysis from Miles and Huberman. The results of this study indicate that the story of Uttarakānda Ramāyāna contains many moral messages that are useful for life. It is hoped that this research can be an initial provision for someone who is just learning the Vedas, then they can become a better person through the moral message they receive.
Menyama Braya dalam Upanisad
Authors: Fatmawati Komang
Published: January 2022

This paper aims to convey an understanding of Brama Brama in the view of Upanishad. Upanisad is a book that cannot be separated from the Vedic scriptures. Even each part of the Chess Weda Samhita each has an Upanishad, albeit with different amounts. There are so many teachings contained in the Upanishads, one of which is the teachings on norms that teach about harmonization of life both human and human, human beings with God, and humans with the natural surroundings. Humans other than as individual beings are also at the same time as social beings where humans need interaction with other humans in order to meet their needs. Tri Hita Karana which in its division is Pawongan which means a harmonious relationship between humans and humans. The interactions that occur in Balinese Hindus are not only the application of the teachings of Tri Hita Karana but also as the application of the teachings of Tat Tvam Asi.
REVITALISASI PEMBELAJARAN PENDIDIKAN AGAMA HINDU DI ERA DISTRUPSI DIGITAL
Authors: Kusumawati Niluh Ari
Published: January 2022

In the era of digital disruption, the development of science and technology is very rapidly increasingly encouraging reforms in various fields, especially in the field of education in utilizing the results of technology itself in the learning process. Religious education is a compulsory subject that is applied at every level of education. One of them is the learning subject of Hindu religious education. Revitalization of Hindu religious education learning in the era of digital disruption must continue to be encouraged so that superior Hiindu human resources are realized. Educators are currently required to be able to master various technologies so that they are able to use the various learning facilities provided in schools. Educators are required to develop skills by making interactive learning media by utilizing available educational technology. Effective learning requires good planning before the learning process is carried out. Every educator is required to be able to create interactive learning media. Currently, teachers are also required to have various soft skills that can be used to support the learning process. The complex problems in learning Hindu religious education include the system of learners, educators and students. So that innovation and progress in learning Hindu religious education can be realized. Revitalization of Hindu religious education learning is expected to be able to face the challenges of Hindus in the realm of education easily. So that various elements ranging from the younger generation to the elderly can work together to build a better Hindu religious education and create superior Hindu human resources (HR) so that the goals of national education can be achieved.
Penerapan Pendidikan Karakter Berbasis Budaya Terhadap Siswa Sekolah Dasar Dalam Upaya Peningkatan Mutu Pendidikan Agama Hindu
Authors: Rismayanti Sari Dewi Putu Wiwik
Published: January 2022

Globalization is caused by technological developments, economic progress and the sophistication of information facilities. The aforementioned conditions have had a positive impact as well as a negative impact on the Indonesian nation. The reality is that this is the biggest challenge for the world of education today. In fact culture cannot be separated from education, even culture is the basis or basis of education. This formula reaches far into the future, because it is said that education is not only based on an aspect of culture, namely the intellectual aspect, but also on culture as a whole. The culture on which this education is based must be national in nature. Thus the culture in question is real culture, namely the culture that lives in the Indonesian national society. This picture interrupts us to really pay attention to the importance of character building based on culture (Character building), with the development of technology in this era of digitalization, we are able to create students with culture-based characters and not abandon the development of the times, but use the development of this digitalization era to preserve, develop innovation with creativity that is owned to keep loving the heritage of our ancestors
DAMPAK VIRUS CORONA (COVID-19) TERHADAP KEHIDUPAN SOSIAL BUDAYA MASYRAKAT HINDU BALI (PERSPEKTIF PENDIDIKAN AGAMA HINDU)
Authors: Murdiana I Ketut Agus
Published: January 2022

The Coronavirus (Covid -19) has been declared a Pandemic by the World Health Organization or what is called the World Health Organizer (WHO), because it has spread to almost all countries in the world. Efforts to contain the spread of this virus are continuously being carried out, but in implementation it is inevitable that new impacts or problems will arise in the adjustment. For this reason, further research is needed in order to reveal the impacts arising from the adjustment of people's lives to the epidemic disaster management efforts. In this study, the research location was carried out in Bali. The approach in this study is a descriptive qualitative approach, which will explain the picture of the socio-cultural life of the Balinese Hindu community in the midst of the Covid -19 Pandemic. This study aims to determine the effects of the Covid-19 Pandemic so that it can be used as learning in the future to face similar disasters. The effects of this Pandemic are also studied from the perspective of Hindu religious education. As a result of the arrival of the Coronavirus (Covid -19), many significant changes have occurred in Bali. The results showed that the socio-cultural life of the Balinese people followed new adjustments or adaptations to anticipate the development of the Corona virus disease (Covid -19) outbreak. These adjustments include regulations, religious activities (regarding traditions) and social activities
MENGURANGI DEGRADASI MORAL DAN PENGUATAN KARAKTER ANAK MELALUI PERAN CATUR GURU DI TENGAH PANDEMI COVID-19
Authors: Sri Suandari Putu Febri , Selasih Ni Nengah
Published: January 2022

        Education is one of the most important things that is able to be a change in the world and in changing the younger generation to be better and have character. With the existence of an education that is complemented by religious teachings it self, it will streng then character and reduce the moral and ethical degradation or decline that occurs in every nation's future child. Cultivators of noble moral values, ethics and religious teachings must be planted from an early age so that children become accustomed to them and are able to understand behaviors that should be avoided and prohibited. Therefore the role of parents is very influential on the character of the child because the family is the primary or primary education that the child gets. In addition, to reduce the current moral degradation or deterioration that is prevalent in life, there is a need for cooperation between parents, educators and the government to be able to create a good young generation. In the teachings of Hinduism, there are many teachings that can be used as a guide for life and can be used as character strengthening for children and the younger generation, one of which is known as the teaching of Catur Guru, which is the teaching of how to be devoted, ethical and respecting these four teachers, including self-help teachers. , rupaka teachers, recitation teachers and wisesa teachers.
MODERASI BERAGAMA DALAM KEBERAGAMAN DIMASA COVID-19 “PANDANGAN PENDIDIKAN HINDU”
Authors: Suasta I Wayan
Published: January 2022

Aktivitas kehidupan masyarakat dimasa pendemi covid-19, kini dilakukan melalui media daring. Hal itu dilakukan karena keterbatasan ruang gerak akibat pandemi covid-19,memaksa masyarakat menjadi ketergantungan pada informasi yang diperoleh melalui media daring. Begitu masifnya informasi yang terjadi melalui penggunaan media daringsejak pendemi covid-19 melanda dunia, menjadikan masyarakat harus mampu memilah dan memilih informasi secara adil dan bijak supaya tidak terjebak pada ekstremisme dan radikalisme pemahaman agama yang sempit. Disinilah moderasi dalam keberagaman dimasa Covid-19 dapat menjadi dasar pijakan dalam memilah, memilih dan memanfaatkaninformasi secara adil dan bijak.Maka dalam pandangan pendidikan Hindu, moderasi beragama dalam keberagamanadalah paham atau sikap yang menghargai semua tradisi keagaman sebagai kebenaran. Kebenaran tidak milik satu kelompok keyakinan tertentu melainkan milik semua. Semua hak-hak setiap manusia diperhatikan agar semua bisa hidup makmur dan damai. Maka alangkah baiknya jika semua kedamaian dan keharmonisan dapat diwujudkan dalam praktik nyata perilaku beragama, dengan kesadaran bahwa semua manusia hakikatnya adalah sama terdiri dari jiwa-jiwa yang suci. Semua berhak hidup di bumi sesuai dengan keyakinan dan kepercayaan masing-masing, bumi ini adalah rumah bersama semua mahkluk hidup. Maka dengan mantra vedaOm swastiastu, Om anubadrah kertvu yantu visvatah, Om semesta loka sukinoh bhavantu, Om santih, santih, santih, Om, dapat dijadikan prinsif dasar memaknai moderasi beragama dalam keberagaman dimasa Covid-19. 
NILAI PENDIDIKAN DALAM UPACARA NYAMBLEH DI PURA PEREREPAN DESA BATUBULAN KECAMATAN SUKAWATI KABUPATEN GIANYAR
Authors: Supandi I Nyoman Alit
Published: January 2022

NILAI PENDIDIKAN DALAM UPACARA NYAMBLEH DI PURA PEREREPAN
https://acgpubs.org/doc/20220107214746A3-RAFC-2107-2149.pdf
Authors: Denizkara Ayşenur , Atik İlker , Atik Azize , Akarca Gökhan
Published: January 2022

In this study, antibacterial and antifungal properties of four medlar extracts obtained using four different solvents, ethanol, methanol, acetone and water, were investigated. The disk diffusion method was used to determine the antimicrobial effects of the extracts. In addition, minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and minimum fungicidal concentration (MFC) values were determined. The antibacterial effect of the pure water extract of medlar on S. aureus bacteria was found to be high (11.46 mm). In addition, the MIC and MBC values of the pure water extract were determined as 35.15 and 23.39 µg/mL for S. aureus bacteria. When the antifungal effect was examined, the antifungal effect of the pure water extract of medlar against P. crysogenum was found to be high (14.00 mm). The MIC and MFC values of the pure water extract of medlar are 23.43 and 11.72 µg/mL for P. crysogenum, respectively. Therefore, it was concluded that the pure water extract had the highest antimicrobial effect.
hemical Composition and Biological Activity of Ixiolirion tataricum (Pall.) Schult. & Schult.f. var. tataricum.
Authors: Yigitkan Serkan , Akdeniz Mehmet , Yener İsmail , Firat Mehmet , Senturk Kerem , Alkan Huseyin , Yılmaz Mustafa Abdullah , Ozturk Mehmet , Ertaş Abdulselam
Published: January 2022

The role of plants in human life and the importance of plants in the food, drug and cosmetics industry have been increasing nowadays. This study investigates biological and chemical properties of root, branch, leaf, flower and aerial ethanol extracts of Ixiolirion tataricum (Pall.) Schult. & Schult. f. var. tataricum species, consumed as food in the population. The chemical composition of the species has been determined by the LC-MS/MS by specifying total phenolic and flavonoid contents. Antioxidant activity, cholinesterase, urease, tyrosinase, elastase and collagenase inhibitory activities have also been studied. According to the results of LC-MS/MS, quinic acid, protocatechuic acid, p-coumaric acid, and rutin have been detected. The branch ethanol extract contained higher amounts of quininic acid (12.101 µg analyte/g extract) than extracts of leaves, flowers, roots and aerial parts. On the other hand, the leaves ethanol extract exhibited high antioxidant activity in all tests (ABTS: IC50= 57.47±0.86 µg/mL, CUPRAC: A0.5= 66.76±1.86, DPPH: IC50: 119.2±1.52). The species has the potential to be used in the food industry due to its high antioxidant capacity.
Understanding In-Silico Approaches to Design Synthetic Antifungal Peptides to Combat Fungal Infections like Mucormycosis
Authors:   Department of Microbial Biotechnology, Panjab University, Chandigarh, India, T Bajwa , R Sharma ,   Chairperson, Department of Microbial Biotechnology, Panjab University, Chandigarh, India
Published: January 2022

Antimicrobial peptides are the small sized molecule ranging in size from 2 to 9 kDa with expansive range of antimicrobial activity against bacteria, fungi, viruses etc. They are also used as first line of defense against various pathogens. With the emergence of various fungal infections in the present day and uprising antifungal resistance has made the choice of antifungal drugs very limited, the conventional drugs are slowly becoming ineffective to these fungal pathogens. Researchers have turned to these naturally occurring molecules which represent diverse range of functions and structural features but these naturally occurring peptides exhibit high toxicity, instability and low specificity towards the target which can be combatted by using various in silico and computational approaches to design and modify these AMPs in such a way that their efficiency is increased. In this article, we have specifically focused on Mucormycosis infection because of its high mortality rates and a very few synthetic AMPs have been produced against Mucorales considering the severity of this disease and the rapid surge in Mucormycosis cases emerged in the country. In this paper we will discuss about the present scenario of the disease, AMPs as antifungal therapy, role, classification of antifungal peptides, mechanism of action, advantages and limitations of natural AMPs, important physicochemical properties taken into account while designing synthetic AMPs (SAMPs) and the workflow pipeline to characterize and predict potential synthetic AMPs by using the existing web servers, databases and bioinformatics tools to develop new alternatives of conventional drugs available in the market against fungal infections.
Novel Mega Best-Seller Karya Luluk HF Mariposa dalam Kajian Resepsi Sastra
Authors: Intan Tania , Adji Muhamad
Published: January 2022

This study discusses the reception of readers of the mega best-seller novel entitled Mariposa by Luluk HF. The purpose of this study is to (1) describe the reader's responses, (2) describe the horizon of readers' expectations, and (3) describe the factors that cause differences in responses and the horizon of expectations of readers of Mariposa's novel. The method applied is descriptive qualitative. This study uses a reception aesthetic approach that seeks to find consistent reception patterns as a reflection of the way the reader responds to the text. The research data consisted of texts containing the responses of twenty respondents from the data source in the form of the Goodreads reader site. The research results obtained are as follows. First, not all readers respond positively to the intrinsic elements of the novel, especially the characterization of the female protagonist who is considered to show aggressive behavior with a love motive. Second, most of the horizons of readers' expectations do not match the reality in Mariposa. Readings are generally motivated by curiosity because of the hyperbolic labeling of the novel, recommendations from friends, and the discourse of filming the novel. Third, the factors that cause the difference or suitability of the horizon of readers' expectations for the Mariposa novel are knowledge of literature, knowledge of life, and experience of reading literary works.
Kemampuan Menulis Teks Cerita pada Mahasiswa Program Sarjana Pendidikan Bahasa Indonesia Fakultas Keguruan dan Ilmu Pendidikan Universitas Bengkulu
Authors: Yulistio Didi
Published: January 2022

The purpose of this study is to describe the ability to write story texts for students of the Indonesian Language Education Undergraduate Program FKIP Bengkulu University. The scope of this research covers aspects of (1) the suitability of the theme with the content, (2) the structure of the story text, (3) the choice of words (diction), (4) the use of story-style sentences, and (5) the Indonesian Language spelling and handwriting. This research uses descriptive method and quantitative approach. The research population was all students of the Indonesian Language Education Study Program FKIP Bengkulu University in the odd semester of 2018/2019 and the sample was purposive sampling, determining that there were 34 students in semester III-A. Collecting data uses test techniques and instruments in the form of instructions for writing stories with the theme of "love" and guidelines for assessing the ability to write stories based on five components, including content, text structure, diction, sentences, and mechanics. Data analysis used descriptive statistics to find the mean and determined qualitative results. The results showed that the ability to write story texts for the students of the Indonesian Language Education Undergraduate Program, FKIP Bengkulu University, was categorized as good. This is based on the score of all components with an average of 73.97. These results still require efforts to improve to be better. The results of each aspect of the ability to write story texts, namely aspects (1) the suitability of the theme with the content, good category (18.94), (2) story structure, good category (16.09), (3) accuracy of diction in good category (score 14 ,3), (4) narrative language style sentences are in good category (17.24), and (5) mechanics (BI spelling and handwriting) are in good category (7.32).
Cap analysis of gene expression reveals alternative promoter usage in a rat model of hypertension
Authors: Dahale Sonal , Ruiz-Orera Jorge , Silhavy Jan , Hübner Norbert , van Heesch Sebastiaan , Pravenec Michal , Atanur Santosh S
Published: January 2022

The role of alternative promoter usage in tissue-specific gene expression has been well established; however, its role in complex diseases is poorly understood. We performed cap analysis of gene expression (CAGE) sequencing from the left ventricle of a rat model of hypertension, the spontaneously hypertensive rat (SHR), and a normotensive strain, Brown Norway to understand the role of alternative promoter usage in complex disease. We identified 26,560 CAGE-defined transcription start sites in the rat left ventricle, including 1,970 novel cardiac transcription start sites. We identified 28 genes with alternative promoter usage between SHR and Brown Norway, which could lead to protein isoforms differing at the amino terminus between two strains and 475 promoter switching events altering the length of the 5′ UTR. We found that the shift in Insr promoter usage was significantly associated with insulin levels and blood pressure within a panel of HXB/BXH recombinant inbred rat strains, suggesting that hyperinsulinemia due to insulin resistance might lead to hypertension in SHR. Our study provides a preliminary evidence of alternative promoter usage in complex diseases.
Unexposed populations and potential COVID-19 hospitalisations and deaths in European countries as per data up to 21 November 2021
Authors: Chapman Lloyd A C , Barnard Rosanna C , Russell Timothy W , Abbott Sam , van Zandvoort Kevin , Davies Nicholas G , Kucharski Adam J
Published: January 2022

We estimate the potential remaining COVID-19 hospitalisation and death burdens in 19 European countries by estimating the proportion of each country’s population that has acquired immunity to severe disease through infection or vaccination. Our results suggest many European countries could still face high burdens of hospitalisations and deaths, particularly those with lower vaccination coverage, less historical transmission and/or older populations. Continued non-pharmaceutical interventions and efforts to achieve high vaccination coverage are required in these countries to limit severe COVID-19 outcomes.
Automatic Monitoring System Designed for Controlling the Stability of Underground Excavation
Authors: MAŁKOWSKI Piotr , NIEDBALSKI Zbigniew , BEDNAREK Łukasz
Published: January 2022

Ensuring the stability of mining excavations is a crucial aspect of underground mining. For thispurpose, appropriate shapes, dimensions, and support of workings are designed for the given mining andgeological conditions. However, for the proper assessment of the adequacy of the used technical solutions,and the calibration of the models used in the support design, it is necessary to monitor the behavior of theexcavation. It should apply to the rock mass and the support. The paper presents the automatic systemdesigned for underground workings monitoring, and the example of its use in the heading. Electronicdevices that measure the rock mass movements in the roof, the load on the standing support, and on bolts,the stress in the rock mass, are connected to the datalogger and can collect data for a long of time withoutany maintenance, also in hard-to-reach places. This feature enables the system to be widely used, inparticular, in excavations in the vicinity of exploitation, goafs, or in the area of a liquidated exploitationfield.