bluuebunny/crossref_metadata_2025 huggingface dataset:
Conocimiento de las implicancias éticas de las medidas de salud pública por parte de los tomadores de decisión del Ministerio de Salud Pública de Uruguay
Authors: Sánchez Varela Delia María
Published: June 2018

Se realizó una encuesta a tomadores de decisión de áreas clave del Ministerio de Salud Pública del Uruguay para saber si identificaban los dilemas éticos presentes en la literatura sobre ética de la salud pública, si tenían formación o conocimiento en ética de la salud pública y qué mecanismos utilizaban para la toma de decisiones.Se mostró que todos eran capaces de reconocer los principales dilemas éticos de sus áreas de responsabilidad, a pesar de no contar con formación en bioética y no conocer en su mayoría a los autores del campo. Se constató también que la mayoría se percibían como técnicos, no como políticos, y que los criterios predominantes para la toma de decisiones se basaban en análisis de riesgo-beneficio. La preocupación por la equidad en el acceso a prestaciones de salud apareció en todos los entrevistados.
Bioética y prácticas de salud pública
Authors: Peguero Matilde
Published: June 2018

El método de estudio de la bioética hace referencia a deberes y valores que debe ser cumplido para el respeto a la vida. El objetivo del presente artículo es presentar una reflexión sobre la bioética y acciones de salud pública. Es un artículo de revisión que incluye autores con diferentes posturas. La bioética a pesar de su aparente enfoque individual es vital para cumplimiento de las funciones esenciales en salud pública, garantía del derecho a la salud y respecto a la dignidad humana.
The The social network analysis and its contribution to the mapping of scientific production in postgraduate programs
Authors: Correia da Silveira Batista Haydée Maria , Rodriguez y Rodriguez Martius Vicente , Wandresen Cardoso Keren Ane , Costa Helder Gomes , Dias Ana Claudia
Published: June 2018

This article aims to identify the contribution that the Social Network Analysis (SNA) can offer to the construction of the scientific production in postgraduate programs in Federal Institutions of Higher Education in Brazil. For that, a qualitative and quantitative analysis of 184 dissertations of a stricto sensu postgraduate program of the Federal Fluminense University, during the period from 2015 to 2016, was carried out, emphasizing its network of relationships focused on knowledge areas and on the respective teachers as counselors, participants and guests of the thesis defenses, using the Ucinet software. Based on the literature review, a detailed analysis of the academic work of these two years was also elaborated based on the data registered in the Capes Platform, Sucupira database and on the website of the Laboratory of Technology, Business Management and Environment of the Fluminense Federal University (LATEC / UFF). The themes of the areas of knowledge, trends, and evolution were also analyzed over the periods studied. It is concluded that the results of this system applied in a case, demonstrated the feasibility of the evaluation of the individual attributes and also of the networks as a whole, offering a comparative of their evolution in these two periods explored, thus demonstrating the valuable contribution of SNA in scientific production. This study revealed, at the time of the research, the construction of a first academic social network in this postgraduate program.
Application of Agent Based Simulation to analyze the impact of tax policy on soybean supply chain
Authors: Viégas De Rosis Carlos Henrique , De Mesquita Marco Aurélio
Published: June 2018

This work seeks to explore and demonstrate the use of Agent Based Simulations (ABS) in modelling and simulating supply chains. Such methodology was applied to develop a model to evaluate the impact of current tax policies in soy supply chain in Brazil. The model brought interesting insights on how the country’s current tax structure induces logistics and tributary trade-offs, therefore generating a suboptimal grain distribution. This is accomplished by going through the conception and implementation of an Agent Based Model. First there is the definition and delimitation of the main agents acting upon soy’s supply chain, such as producers, trader and consumers. Those agents then have their behaviors studied and translated into programable patterns. Finally, the model considers the environmental interactions with the mentioned players, including the effects of infrastructure capacities, transportation costs, storage costs and tax legislation. After quantitative and behavioral validation, the simulation is then able to mimic the actual allocation of corn, soy and soymeal productions in their respective supply chains. This would allow inferring how the system could work in different tax conditions, thus quantifying the tributary impact in terms of congestions, idle infrastructure and delays. The analysis of such results points out that a path dependant tax system may induce agents to opt for inefficient logistic solutions, if such alternatives are cheaper when taking taxes into account. From those simulations it is possible to conclude that there are opportunities for supply chain efficiency gains in the design of a new tax policy.
Globalization and changing nursing workforce within the framework of flexibility model
Authors: Öncü Emine
Published: June 2018

Globalization was developed as a response to the capitalism’s great economic crisis in the 1970’s. During this period, the social state implementations were abandoned amid increasing competitive conditions, and flexible employment model shaped through neoliberal policies became dominant in the working life. Healthcare industry, which was not very interesting for the capitalist class up until then became another focal point to yield further profits and the 40 years that passed since became an economic industry. Under the competitive free market order, minimized state intervention, privatization and flexibility applications narrowed the gap between public and private, insecure work, increasing obscurity and duration of in working hours, obscurity in job descriptions, outsourcing, performance-based remuneration changed the work life and working conditions of healthcare employees. Nursing should not be considered apart from the system, outside of these applied policies. Therefore, nurses should be aware of these implemented policies and the effects of globalization.
The Concept of ‘Matter’ in Archaic Greece, 1: Khaos/Aèr in Hesiod’s Theogony
Authors: Cerri Giovanni
Published: June 2018

The essay considers synthetically the passages of Hesiod’s Theogony concerning Khaos, Gaia, Uranòs, and Tàrtaros as describing the cosmic structure at its very beginning and at its present state. The final result of the cosmogenetic process consists of three solid parallel disks of equal size separated from one another by the space of Khaos/Aèr. The whole structure is conceived of as an ideal cylinder (ideal because it has no real lateral walls), whose superior base is Uranòs (the Sky), the inferior one is Tàrtaros (the Hell) and the median section is Gaia (the Earth), dividing the whole cylinder into two high semicylinders full of Khaos/Aèr. From this Khaos/Aèr, the primal Four Elements (earth, water, misty air and fire) derive, as plants do from their roots, from which all other substances of the universe originate in turn. Thus, Khaos is arkhè (the ‘beginning’) not only in the chronological-historical sense, but also in the sense of an eternal generative substance of all things. We may conclude that the Hesiodic word khaos is a lexical ancestor of the later physical and philosophical term hyle because it conveys the primeval notion of ‘matter’.
Argument and Performance: Alcibiades’ Behavior in the Symposium and Plato’s Analysis in the Laws
Authors: Erler Michael
Published: June 2018

Argument and literary form, and how they both relate to each other, are crucial aspects of any interpretation of the Platonic dialogues. Plato the author and Plato the philosopher always work hand in hand in that Plato the author tries to serve Plato the philosopher. It is, therefore, an appropriate principle for approaching the study of Plato’s philosophy to take into account the literary aspects of the dialogues and to ask how Plato’s literary art of writing could possibly support his philosophical message and, for instance, to consider what this relation means in the context of the debate about developementalism versus unitarianism in Plato’s philosophy. In the present paper , I argue that the performance of the characters plays an important role in this context. I discuss various passages in the Laws which analyse the weakness of the will and I compare what Plato says there with the performance of Alcibiades in the Symposium. I conclude that the passages in the Laws can be read as a kind of commentary on Alcibiades’ behavior and I consider what this relation means in the context of the debate about developementalism versus unitarianism in Plato’s philosophy.
Τὸ καλόν as a Criterion for Evaluating Innovation (τὸ καινόν) in Greek Theory of Musical Education: “Ancient” versus “New” Music in Ps. Plut. De musica
Authors: Gostoli Antonietta
Published: June 2018

The Pseudo-Plutarchan De musica provides us with the oldest history of Greek lyric poetry from the pre-Homeric epic poetry to the lyric poetry of the fourth century B.C. Importantly, the work contains also an evaluation of the role of music in the process of educating and training the citizens. Ps. Plutarch (Aristoxenus) considers the καλόν in the aesthetic and ethical sense, which makes it incompatible with the καινόν dictated by the new poetic and musical season.
Evil as Privation in Neoplatonism. Simplicius and Philoponus in Defense of Matter
Authors: Cardullo R. Loredana
Published: June 2018

The aim of this paper is to highlight the decisive contribution of Simplicius and Philoponus to the resolution of the problem of evil in Neoplatonism. A correct and faithful interpretation of the problem, which also had to agree with Plato’s texts, became particularly needed after Plotinus had identified evil with matter, threatening, thus, the dualistic position, which was absent in Plato. The first rectification was made by Proclus with the notion of parhypostasis, i.e., “parasitic” or “collateral” existence, which de-hypostasized evil, while at the same time challenging the Plotinian theory that turned evil into a principle that was ontologically opposed to good. In light of this, the last Neoplatonic exegetes, Simplicius and Philoponus, definitely clarified the “privative” role of kakon, finally relieving matter from the negative meaning given to it by Plotinus and restoring metaphysical monism.
Shane and the Language of Men
Authors: Ulmer Jesse Gerlach
Published: June 2018

Jane Tompkins has argued that a deeply conflicted relationship exists between men and language in the Western. Deploying too much language emasculates Western heroes, men who privilege action over talk. For support, Tompkins turns to a number of moments in Shane, the 1953 film adaptation of the 1949 novel of the same title by Jack Schaefer. Tompkins argues that the film constructs a model of masculinity that wholly rejects language, a move that is destructive and exploitative to self and others. However, a close reexamination of the novel reveals a model of masculinity that is more positive and flexible towards language and gender than Tompkins’s views on the Western suggest. A close rereading of the novel shows that men in Westerns do not always use talk and silence to subjugate women and others, and that the valuing of language over action does not always end in violence or exploitation. Furthermore, the film adaptation of the novel will be examined, a work that occupies a more cherished place in American culture than the novel, a situation that is the reverse of traditional cultural hierarchies in which the literary source material is privileged over the film adaptation. Ultimately, the novel and film are engaging in different ways, yet Schaefer’s novel, rather than being relegated to middle school literature classrooms, rewards serious critical and scholarly attention, particularly in the context of the film adaptation and critical discourse on the representation of masculinity in the Western.
Warum „ekelhaftestes Film-Machwerk“?
Authors: Weissmann Dirk
Published: June 2018

From an intermedial point of view, this paper deals with a hitherto neglected aspect of Elias Canetti’s The Voices of Marrakesh (1968). As I will show, Canetti’s travel log, written after a trip to Morocco in 1954, is closely related to contemporary films, starting with Gavin Lambert’s Another Sky, a movie shot during Canetti’s stay. On the basis of three examples, my paper argues that such films can contribute to a new and better understanding of the specificities of the author’s view of the Moroccan city.
Effect of chronic high-intensity exercise on hunger and satiation and levels of acylated ghrelin and leptin in women
Authors: Koshki Mahmoud Hesar , Mollanovruzi Azam , Lamir Amin Rashid
Published: June 2018

Study aim: The purpose of this study was to investigate the effect of chronic high-intensity exercise training on hunger, satia­tion, related hormones and weight loss among women who are obese or overweight. Material and methods: The sample group was composed of 25 subjects, divided into two groups: a high-intensity exercise group (n = 15) intensity of 80-90% of maximum heart rate and a non-training control group (n = 10). The blood sample test was performed in two stages of rest, fasted state and before breakfast and an appetite questionnaire was completed. The training procedure was a high-intensity exercise, three sessions a week for twelve weeks and two hours after breakfast. Independent and dependent t-tests were used to analyze the data. Results: The results showed that high-intensity exercise caused a significant loss of weight (p = 0.01) and fat percentage (p = 0.001) and plasma insulin levels (p = 0.03), but it had no effect on hunger and satiation, calorie intake or plasma leptin. Also, it significantly increased the plasma acylated ghrelin (p = 0.04) and maximum oxygen consumption (p < 0.001). Conclusions: Based on the results of this study, it can be noted that high-intensity exercise is suitable for weight loss and not increasing hunger. The lack of calorie intake along with weight loss showed that negative energy balance caused no appetite compensatory responses. Also, high-intensity exercise stimulates physiological responses to increase appetite, but it did not affect the feeling of appetite. In other words, changes in mental and physiological appetite because of high-intensity exercise do not match.
Procalcitonin-guided antibiotic therapy: an expert consensus
Authors: Bartoletti Michele , Antonelli Massimo , Bruno Blasi Francesco Arturo , Casagranda Ivo , Chieregato Arturo , Fumagalli Roberto , Girardis Massimo , Pieralli Filippo , Plebani Mario , Rossolini Gian Maria , Sartelli Massimo , Viaggi Bruno , Viale Pierluigi , Viscoli Claudio , Pea Federico
Published: June 2018

Background:

Procalcitonin (PCT) is a useful biomarker of bacterial infection and its use is associated to reduced duration of antibiotic therapy in the setting of intensive care medicine. To address the need of practical guidance for the use of PCT in various clinical settings, a group of experts was invited to participate at a consensus process with the aims of defining the rationale for appropriate use of PCT and for improving the management of critically ill patients with sepsis.

Methods:

A group of 14 experts from anesthesiology and critical care, infectious diseases, internal medicine, pulmonology, clinical microbiology, laboratory medicine, clinical pharmacology and methodology provided expert opinion through a modified Delphi process, after a comprehensive literature review.

Results:

The appropriateness of use of PCT in terms of diagnosis, prognosis and antimicrobial stewardship was assessed for different scenarios or settings such us management of infection in the emergency department, regular wards, surgical wards or in the intensive care unit. Similarly, appropriateness and timing of PCT measurement were evaluated. All the process consisted in three Delphi rounds.

Conclusions:

PCT use is appropriate in algorithms for antibiotic de-escalation and discontinuation. In this case, reproducible, high sensitive assays should be used. However, initiation or escalation of antibiotic therapy in specific scenarios, including acute respiratory infections, should not be based solely on PCT serum levels. Clinical and radiological findings, evaluation of severity of illness and of patient’s characteristics should be taken into proper account in order to correctly interpret PCT results.
Special Input Devices Integration to LIRKIS CAVE
Authors: Hudák Marián , Korečko Štefan , Sobota Branislav
Published: June 2018

LIRKIS CAVE is a unique immersive virtual reality installation with a compact cylinder-based construction and a high-quality stereoscopic video output rendered on twenty 55” Full HD LCD panels. While the video output of the CAVE provides a high level of immersion to a virtual world, its original implementation of peripherals support had a negative impact because of a limited number of supported devices and certain performance issues. In this paper we describe a new, distributed, peripheral devices support implementation for the LIRKIS CAVE, which solves the performance issues and allows for ease of integration of new input devices into the CAVE. We also present a successful integration of a special input device, the Myo armband,which allows a natural and unobtrusive gesture-based control of virtual environments. The integration includes a newly developed control and monitoring application for the Myo, called MLCCS, which utilization is not limited to CAVE systems or virtual reality applications.
Global attractivity for Volterra type Hadamard fractional integral equations in Fréchet spaces
Authors: Abbas Saïd , Agarwal Ravi P. , Benchohra Mouffak , Berhoun Farida
Published: June 2018

In this paper, we present some results concerning the existence and the attractivity of solutions for some functional integral equations of Hadamard fractional order. We use an extension of the Burton-Kirk fixed point theorem in Fréchet spaces.
Youth Ministry Research and the Empirical
Authors: de Kock Jos , Hallesby Norheim Bård E.
Published: June 2018

The aim of this article is to discuss how one can understand empirical observations as a starting point for practical theological research, which is geared towards developing theological reflection, with a particular focus on the faith practices of children and young people. Three basic skills are suggested as keys in scholarly engagement with children and young people: observation as reception, listening as reception, and the importance of learning language. The authors show what happens theologically when youth ministry scholars apply these skills in practical theological research that focuses on the faith practices of young people.
Growth and Quality of Green Bean (Phaseolus vulgaris L.) under Foliar Application of Organic-Chelate Fertilizers
Authors: Aslani Maryam , Souri Mohammad Kazem
Published: June 2018

Organic-based chelate fertilizers can effectively improve nutrient uptake and use efficiency of plants. In the present study, foliar applications of three organic-chelate fertilizers on green bean (Phaseolus vulgaris L.) plants were compared to soil application of a mix chemical fertilizer (NPK) under greenhouse conditions. The treatments were foliar application (six sprays at 0.2% concentration) of Biomin, Humifolin, DelfonPlus, a mixture of micro and macronutrients, soil application of chemical fertilizer (NPK 0.5 g.kg-1 soil), and no fertilizer control. Foliar applications of organic-chelate fertilizers improved plant height, leaf area, shoot dry weight, leaf N and K concentration, pod number and pod yield compared to control plants. Pod soluble solids, vitamin C and total protein contents were significantly increased by foliar application of organic-chelate fertilizers. Soil applied NPK also improved green bean productivity compared to no fertilizer control. For most plant growth traits, there was no significant difference among the three organic-chelates. Foliar application of the macro- micro- nutrient mixture was not able to enhance the same growth, yield and pod quality traits like organic-chelates. Therefore, application of nutrient elements in form of organic-chelate and particularly by foliar application can guarantee better green bean plant performance.
Mechanical, Microstructural and Thermal Characterization of Epoxy-Based Human Hair–Reinforced Composites
Authors: Verma Akarsh , Singh V. K.
Published: June 2018

Owing to their biodegradable nature and cost-effectiveness, natural fibers have attracted the attention of various material scientists. One such fiber is human hair (HH), which is viscoelastic-plastic in nature and encloses well-characterized microstructures within it. An important aspect is that a strand of HH having a diameter of 60 μm is capable of withstanding a force of 100–150 grams/fiber. However, wastage of HH on an enormous scale poses an environmental challenge. Therefore, the authors have utilized this novel fiber in the field of composites and revealed the systematic methodology of fabricating HH with polymers using the wet hand lay-up technique. The diverse compositions of polymer-HH composite, with varying HH weight percentages (wt.%) of 5, 6, 7, 8, 9, and 10 %, were put to investigation. In the present work, treatment of HH with potassium hydroxide and curing of polymer further enhanced the bonding properties of composites. The specimens were examined micro-structurally through scanning electron microscopy (SEM) and X-ray powder diffraction (XRD) tests, followed by the mechanical tests: tensile, compression, flexural, hardness, and impact. Both the microstructural and mechanical tests complemented each other and confirmed that the cured polymer composite speckled with 7 wt.% of HH fiber content was the best of all formulations, as it provided the highest magnification in mechanical properties relative to neat polymer. Finally, the thermal analysis was done via thermal gravimetric analysis (TGA) and differential thermal analysis (DTA) techniques.
Experimental Evaluation of Consolidation Behavior of Double-Layer Soft Soil Ground
Authors: Lei Huayang , Ren Qian , Jiang Yan , Jiang Mingjing
Published: June 2018

Double-layer grounds are characterized by one layer of soft soil on the top of another, which are frequently encountered in land reclamation projects in China. Consolidation behavior of the double-layer grounds is complicated compared with that of single-layer soil because of the complex drainage conditions that exist between two soil layers and the different consolidation properties of the two soils. The consolidation behavior of the double-layer ground becomes more complicated when it is subjected to a surcharge preloading. Therefore, it is necessary to understand the consolidation behavior of individual soils that make up the double-layer ground as well as the double-layer ground as a whole. In this article, double-layer specimens were prepared to simulate double-layer grounds, which include an upper layer clay with high plasticity and a lower layer clay with low plasticity. Consolidation tests were performed on both single-layer specimens and double-layer specimens using a modified consolidation test device. The influences of surcharge ratio and surcharge preloading duration on the consolidation behavior of double-layer ground, such as consolidation settlement and consolidation rates, were studied in addition to the influence of the thickness ratio (i.e., the ratio of the thickness of the upper layer of soil to the lower layer of soil). The experimental results show that a longer surcharge preloading duration could reduce the time needed to complete the rebound of the double-layer ground. The secondary consolidation settlement of double-layer ground can be reduced by increasing either the surcharge ratio or surcharge preloading duration. In addition, an increase in the thickness ratio could result in an increase in the primary consolidation settlement and a decrease in the consolidation rate. However, the effect of the thickness ratio on the consolidation settlement and the consolidation rate gradually decreased with the increase in the thickness ratio.
Aplicação do projeto “Bisfenol A (BPA): Uma ameaça invisível para você e sua família” em escolas municipais e estaduais de Rio Grande, RS
Authors: Da Silveira Cássia Rodrigues , Barreto Juliano , Nunes Silvana Manske , Chaves Isabel , Martínez Pablo
Published: June 2018

Atualmente, a indústria alimentícia utiliza embalagens plásticas e enlatadas para acondicionar seus produtos. No processo de fabricação de plásticos de policarbonato e latas revestidas com resinas epóxi é utilizado o Bisfenol A (BPA), que por sua vez, acaba migrando de embalagens plásticas ou enlatadas para o alimento, e é consumido diariamente pela população. O BPA pode contribuir para efeitos diversos como Transtorno do Déficit de Atenção e Hiperatividade (TDAH), obesidade, alterações reprodutivas e endócrinas. A presença do BPA foi detectada no soro, placenta e urina humana. Sendo assim, o objetivo desse trabalho foi divulgar e informar sobre os efeitos do BPA para crianças em escolas municipais e estaduais da cidade de Rio Grande - RS. Para isso, foram elaborados questionários e panfletos com informações sobre os efeitos do BPA, distribuídos durante visitas realizadas em escolas de Rio Grande. Além disso, foi ministrada uma palestra falando sobre os efeitos do BPA e de outros contaminantes presentes no dia a dia, durante as visitas. O recebimento da campanha foi considerado satisfatório, bem como, o aprendizado dos alunos sobre o tema, que foi medido através da análisede questionários de antes e após a palestra.
INTERVENÇÕES ASSISTIDAS POR ANIMAIS REALIZADAS EM AMBIENTE HOSPITALAR NA PROMOÇÃO DO CUIDADO COM A VIDA
Authors: Lima Camila Moura de , Krug Fernanda Dagmar Martins , Bender Daniele Dornelles , Rodrigues Mara Regina Marques , Mechereffe Beatriz Maksud , Vieira Ana Cláudia Garcia , Capella Sabrina De Oliveira , Nobre Márcia De Oliveira
Published: June 2018

A Intervenção Assistida por Animais é um método que utiliza os animais como mediadores de um processo terapêutico. Dessa maneira, essa prática pode ser utilizada em diversos públicos de pacientes como estratégia na promoção do cuidado com a vida. Diante dos diversos benefícios, que essa interação pode proporcionar aos seres humanos, o objetivo deste estudo foi verificar os benefícios das Intervenções Assistida por Animais, realizada em pacientes hospitalares e psiquiátricos na cidade de Pelotas. Assim, as atividades realizadas ocorreram semanalmente, por um período de um ano. E a cada intervenção participavam em média cinco assistidos e também três cães co-terapeutas. Nesse contexto, foram evidenciados inúmeros benefícios para as crianças hospitalizadas, seus acompanhantes e também para os pacientes psiquiátricos. A presença dos cães amenizou a saudade de casa, despertando sentimentos de empatia, afeição e melhora de humor. Conclui-se que, as intervenções assistidas por animais realizadas em pacientes hospitalares em ambas instituições da cidade de Pelotas, foram realmente benéficas. Pois, foram constatados pelos profissionais envolvidos inúmeros benefícios, como a interação social, mudança de humor, melhora na motricidade e na qualidade de vida.
Museu De Ciências Da Vida: A Construção Da Cientificidade Diante A Existência Do Ser
Authors: Silveira Rogério Zanon da , Carvalho Sandra Maria Souza de
Published: June 2018

O ensaio visual apresenta fotografias envolvendo ambiência, ações e exposições do Museu Ciência da Vida (MCV) no município de Vitória, Espírito Santo. Trata-se de um projeto de extensão e de produção de saberes da Universidade Federal do Espírito Santo (Ufes) que completa 11 anos de existência. A orientação museológica versa a área temática da educação, área afim cultura e a linha de extensão aborda a questão da divulgação científica e tecnológica com enfoque nas ciências biológicas. Essa memória visual de extensão mostra que os modelos tridimensionais, microscópio óptico e demais recursos tangíveis dessa entidade proporcionam aos visitantes múltiplas experiências: estimula-se a curiosidade e o aprendizado a cerca do cuidado com a vida; gera novas perspectivas de vida, descobrindo e despertando vocações; aguça a consciência de cidadania e direitos humanos.
Ações de Prevenção do Câncer em Pequenos Animais pelo Serviço de Oncologia Veterinária da Universidade Federal de Pelotas (SOVET- UFPel)
Authors: Berselli Michele , Tillmann Mariana Teixeira , Hoff Vitória Daudt , Castro Clarissa Caetano de , Rossato Andressa Dutra Piovesan , Silva Luísa Mariano Cerqueira da , Guim Thomas Normanton , Fernandes Cristina Gevehr
Published: June 2018

O objetivo desse trabalho é relatar as ações realizadas pelo SOVET- UFPel para conscientizar a população quanto ao câncer em animais. A iniciativa surgiu da necessidade de alertar a população sobre a prevenção, diagnóstico e tratamento do câncer em animais. O Serviço em Oncologia Veterinária da Universidade Federal de Pelotas (SOVET- UFPel) juntamente com outras instituições no país construíram inicialmente a Campanha Nacional contra o Câncer de Mama em Animais. Assim sendo, desde o ano de 2014, tem-se realizado um evento final no mês de outubro ou início de novembro. Esta ação foi baseada na campanha Outubro Rosa de humanos. Nesta ação são abordados conceitos básicos de prevenção, diagnóstico e tratamento do câncer em pequenos animais de forma lúdica e interativa. O convite para os eventos ocorridos foi realizado através de planfletagem pelos discentes do curso de medicina veterinária, que foram previamente treinados para a abordagem da população, além de inserções em mídia impressa, televisão e redes sociais, conduzidas pelos coordenadores do grupo. A partir do ano de 2016, a campanha foi ampliada para conscientizar também sobre o câncer de pele e do trato genital masculino, sendo então realizado em novembro usando como base a campanha do Novembro Azul para humanos. Durante esses anos também foram ministradas palestras lúdicas em escolas para as séries iniciais, e nove palestras técnicas para os discentes de veterinária. Também houve a participação do SOVET-UFPel em eventos promovidos por diferentes grupos, como pet shops/clínicas veterinárias, em diferentes pontos da cidade. As atividades realizadas pelo SOVET conscientizaram a população, pois a procura pelos serviços oncológicos prestados pelo grupo na área de clínica e diagnóstico patológico teve um aumento de 68,85% ao longo desses quatro anos.
O PROCESSO SAÚDE-DOENÇA-CUIDADO À POPULAÇÃO EM SITUAÇÃO DE RUA: INTERVENÇÕES DE ACADÊMICOS DE ENFERMAGEM
Authors: Dias Luiza Jocymara Lima Freire , Brandão Maria Girlane Sousa Albuquerque , Amaral Vitória Ferreira do , Aguiar Maria Iranaid Linhares , Cavalcante Ana Suelen Pedroza , Vasconcelos Maristela Inês Osawa
Published: June 2018

Este estudo tem por objetivo descrever atividades realizadas com pessoas em situação de rua assistidas por um Centro POP de um município da Região Norte do Estado do Ceará. O projeto de intervenção refere-se à experiência de acadêmicos do curso de Enfermagem de uma Universidade no Estado do Ceará, vinculados a atividades de estágio curricular no módulo de Práticas Interdisciplinares em Ensino, Pesquisa e Extensão I (PIEPE I), no período de maio a julho de 2016. O projeto consistiu na realização de um conjunto de intervenções, buscando atingir, enquanto público-alvo, a população em situação de rua participante de um Centro Pop. Foram realizados 15 encontros de intervenção com uma média de 10 participantes. Foram utilizadas metodologias ativas e participativas, onde os participantes puderam interagir com os temas e falar ativamente suas opiniões e expressar suas dúvidas. A realização dessas intervenções em um serviço de apoio às pessoas em situação de rua configurou-se como uma importante estratégia da Universidade para dar um retorno à comunidade e contribuir com uma melhor formação profissional. Logo, essas vivências contribuíram na melhor visualização do indivíduo na sua totalidade, dando enfoque não apenas para as mazelas físicas, mas atentando-se prontamente para os aspectos comportamentais, psicológicos e emocionais dos indivíduos.
Projeto Cuidar-te e Saúde LGBTI: Uma experiência em extensão universitária sobre a saúde da população LGBTI no ensino da Enfermagem
Authors: Pereira Nayla Rodrigues , Cerqueira Ana Rafaela Brito , Cerqueira Naomi Santos , Linares Matheus Oliveira , Gamba Mônica Antar
Published: June 2018

A experiência de extensão universitária de estudantes de enfermagem de uma universidade pública no município de São Paulo no enfrentamento de situações de vulnerabilidade se constitui o escopo desta resenha que integra o projeto de Extensão Cuidar-te, neste caso, sobre a saúde da população LGBTI. A abordagem metodológica utiliza como referência a educação em saúde, como um eixo da saúde coletiva, utilizando a pedagogia problematizadora de Paulo Freire pelas vivências, embasadas em evidências científicas e desenvolvimento da práxis em saúde pelos estudantes. Tais vivências ocorreram em equipamentos da cidade de São Paulo voltados ao atendimento da população LGBTI. A busca de evidências sistematizou os conhecimentos científicos disponíveis na literatura. Para a intervenção prática o grupo fez uma proposição de atuação que culmina na organização de um serviço disponível para o atendimento de saúde da LGBTI no complexo universitário. O Cuidar-te propôs uma disciplina eletiva sobre saúde da população LGBT e a inserção da pós graduanda da área na disciplina de políticas públicas pelo Programa de Aperfeiçoamento Docente (PAD).
Primeiro número da Revista Expressa Extensão
Authors: Pieper Daniela Da Silva , Michelon Francisca Ferreira
Published: June 2018

Nesta entrevista, realizada com a técnica administrativa Daniela Pieper, uma das pessoas envolvidas na criação do primeiro número da Revista Expressa Extensão, são respondidas algumas perguntas sobre como se deu a criação do primeiro número da revista, a proposta inicial do periódico, ideias temáticas, entre outros pontos. A Expressa Extensão é um veículo para os debates que cercam o tema da Cultura interdisciplinar entendida como processo capaz de integrar a universidade com a sociedade. Objetiva discutir a ação extensionista como forma singular no processo de formação do estudante, pela qual o conhecimento apresenta-se como uma ferramenta para a construção do sujeito consciente, nesta revista entendido como o sujeito do conhecimento.
Prolonged diabetic ketoacidosis associated with canagliflozin
Authors: Sloan Gordon , Kakoudaki Tania , Ranjan Nishant
Published: June 2018

We report a case of a 63-year-old man who developed diabetic ketoacidosis (DKA) associated with canagliflozin, a sodium glucose co-transporter 2 (SGLT-2) inhibitor. He presented acutely unwell with a silent myocardial infarction, diverticulitis and DKA with a minimally raised blood glucose level. Standard therapy for DKA was initiated. Despite this, ketonaemia persisted for a total of 12 days after discontinuation of canagliflozin. Glucosuria lasting for several days despite discontinuation of the medications is a recognised phenomenon. However, this is the longest duration of ketonaemia to be reported. The cause of prolonged SGLT-2 inhibition remains uncertain. Deviation from the normal DKA treatment protocol and use of personalised regimens may be required in order to prevent relapse into ketoacidosis while avoiding hypoglycaemia in those that develop this condition.

Learning points:

Diabetic ketoacidosis (DKA) may develop in the presence of lower-than-expected blood glucose levels in patients treated with a sodium glucose co-transporter 2 (SGLT-2) inhibitor.

Certain individuals prescribed with SGLT-2 inhibitors may be more at risk of DKA, for example, those with a low beta cell function reserve, excessive alcohol consumption and a low carbohydrate diet.

In order to reduce the risk of SGLT-2 inhibitor-associated DKA, all patients must be carefully selected before prescription of the medication and appropriately educated.

Increased serum ketone levels and glucosuria have been reported to persist for several days despite discontinuation of their SGLT-2 inhibitor.

Physicians should consider individualised treatment regimens for subjects with prolonged DKA in the presence of SGLT-2 inhibition.
False-positive findings on 6-[18F]fluor-l-3,4-dihydroxyphenylalanine PET (18F-FDOPA-PET) performed for imaging of neuroendocrine tumors
Authors: Berends Annika M A , Kerstens Michiel N , Bolt Janne W , Links Thera P , Korpershoek Esther , de Krijger Ronald R , Walenkamp Annemiek M E , Noordzij Walter , van Etten Boudewijn , Kats-Ugurlu Gursah , Brouwers Adrienne H , van der Horst-Schrivers Anouk N A
Published: June 2018

Background/aim

PET with 6-[18F]fluor-l-3,4-dihydroxyphenylalanine (18F-FDOPA) has been shown to be a useful imaging tool with a high sensitivity for the visualization of neuroendocrine tumors (NETs).18F-FDOPA uptake in tumors other than NETs has been suggested previously, but data on this phenomenon are limited. We therefore studied the non-physiological, false-positive uptake of18F-FDOPA in a large population of patients with a NET or with a high clinical suspicion of harboring a NET.

Patients and methods

Retrospective single-center study among adult patients in whom18F-FDOPA PET scintigraphy was performed between January 2004 and December 2014. The original scan report was compared with the original pathology report corresponding with the18F-FDOPA PET-positive lesion. In case this was inconsistent with the diagnosis of a NET, both the scan and the pathology slides were reassessed. Specimens of these non-NET tissues were immunohistochemically stained for AADC.

Results

107018F-FDOPA PET scans from 705 patients were evaluated. Focal or multiple18F-FDOPA-avid lesions were described in 70918F-FDOPA PET scans (66%). Histology of these18F-FDOPA PET-positive lesions was present in 508 (72%) cases. In seven cases, the histopathology was not compatible with NET but showed squamous cell carcinoma of the cervix, multiple myeloma (two cases), hepatocellular carcinoma, Schwannoma, adrenocortical carcinoma and a skeletal myxoid chondrosarcoma, with positive immunohistochemical staining for AADC in 67%.

Conclusions

Pathological uptake of18F-FDOPA does not always indicate the presence of a NET. The possibility of18F-FDOPA uptake by tumor types other than NETs, although rare, should be considered.
Recent insight into the correlation of SREBP-mediated lipid metabolism and innate immune response
Authors: Park Hyeon Young , Kang Hye Suk , Im Seung-Soon
Published: June 2018

Fatty acids are essential nutrients that contribute to several intracellular functions. Fatty acid synthesis and oxidation are known to be regulated by sterol regulatory element-binding proteins (SREBPs), which play a pivotal role in the regulation of cellular triglyceride synthesis and cholesterol biogenesis. Recent studies point to a multifunctional role of SREBPs in the pathogenesis of metabolic diseases, such as obesity, type II diabetes and cancer as well as in immune responses. Notably, fatty acid metabolic intermediates are involved in energy homeostasis and pathophysiological conditions. In particular, intracellular fatty acid metabolism affects an inflammatory response, thereby influencing metabolic diseases. The objective of this review is to summarize the recent advances in our understanding of the dual role of SREBPs in both lipid metabolism and inflammation-mediated metabolic diseases.
Critical role for the Tsc1-mTORC1 pathway in β-cell mass in Pdx1-deficient mice
Authors: Sun Juan , Mao Liqun , Yang Hongyan , Ren Decheng
Published: June 2018

Mutations in the pancreatic duodenal homeobox (PDX1) gene are associated with diabetes in humans. Pdx1-haploinsufficient mice also develop diabetes, but the molecular mechanism is unknown. To this end, we knocked down Pdx1 gene expression in mouse MIN6 insulinoma cells. Pdx1 suppression not only increased apoptotic cell death but also decreased cell proliferation, which was associated with a decrease in activity of mechanistic target of rapamycin complex 1 (mTORC1). We found that in Pdx1-deficient mice, tuberous sclerosis 1 (Tsc1) ablation in pancreatic β-cells restores β-cell mass, increases β-cell proliferation and size, decreases the number of TUNEL-positive cells and restores glucose tolerance after glucose challenge. In addition, Tsc1 ablation in pancreatic β-cells increases phosphorylation of initiation factor 4E-binding protein 1 (4E-BP1) phosphorylation and 40S ribosomal protein S6, two downstream targets of mTORC1 indicating that Tsc1 mediates mTORC1 downregulation induced by Pdx1 suppression. These results suggest that the Tsc1-mTORC1 pathway plays an important role in mediating the decrease in β-cell proliferation and growth and the reduction in β-cell mass that occurs in Pdx1-deficient diabetes. Thus, mTORC1 may be target for therapeutic interventions in diabetes associated with reductions in β-cell mass.
EFFECTS OF RHEOLOGICAL BEHAVIOR ON CEREAL LEGUMES BLENDED FLOURS
Authors: Ur Rehman Tanzeel , Kamran Sharif Mian , Majeed Majid , Bilal Hussain Muhammad , Usman Khan Muhammad , S. Rodionova Natalya , Ali Shariati Mohammad , V. Shevaldova Tatyana
Published: June 2018

The farinograph and mixograph are the most commonly used empirical instruments to determine three parameters: 1) characterize dough rheology; 2) evaluate dough performance during processing; 3) and quality control. Maize, chickpea, and soybean flours ranging from 10% to 50% (in 10% increments) were blended with wheat flour to prepare composite flours for rheological studies. Mixographic results indicated that as flour percentages increased among treatments, peak times and mixing tolerance indices increased. Farinographic results indicated that as flour percentages increased, an increase in water absorption with a concurrent decrease in development and dough stability times due to less gluten content occurred.
Криптовалюта, как качественно новый платежный инструмент и перспективы ее интеграции в мировую финансовую систему
Authors: Dzhusov Oleksii , Rubtsova Nataliia
Published: June 2018

Цель работы – проанализировать современные тенденции и состояние международного рынка ведущих криптовалют и оценить возможные перспективы их дальнейшего развития и интеграции в мировую финансовую систему.
Результаты исследования. Ретроспективно прослежена история происхождения и становления Биткоина (Bitcoin), рассмотрены некоторые особенности «Блокчейн» («Blockchain»). Проанализированы положительные и отрицательные стороны работы с криптовалютами. Рассмотрена ближайшая по капитализации к Биткоину криптовалюта Эфир (Ethereum) и проанализированы основные различия между ними. На основе проведенного исследования сформирован прогноз о наиболее вероятном направлении развития рынка криптовалют на ближайшее будущее и о возможности их интеграции в мировую финансовую систему.
Теоретическое значение исследования. Настоящее исследование и его результаты будут способствовать решению глобальной научной задачи – формированию научно-обоснованного мнения академической науки к новому феномену в экономике – криптовалютам и их роли в мировой финансовой системе.
Оригинальность/ценность/научная новизна исследования. Работа является одной из немногих, посвященных новому явлению в экономике – криптовалютам; представлены авторские прогнозы о возможных направлениях дальнейшего развития рынка криптовалют.
Перспективы дальнейших исследований. Настоящая работа открывает возможность дальнейших исследований в области рынка криптовалют, его дальнейшего развития и интеграции в мировую финансовую систему.
Тип статьи – эмпирическая.
Development of a high performance batteries charger with low THD, high power factor, and high efficiency
Authors: Sanchez-Choachi Johan Sebastian , Dávila Miguel Ángel , Trujillo Cesar Leonardo
Published: June 2018

Este articulo presenta el diseño, simulación e implementación de un cargador off-board de baterías de mediana y baja capacidad que incorpora un corrector de factor de potencia, alcanza una baja distorsión armónica (THD) en corriente y permite la implementación de tres diferentes estrategias de carga. Este cargador está compuesto de una etapa de aislamiento galvánico, seguida por un puente rectificador el cual es conectado a un convertidor Boost quien regula el factor de potencia y el THD. Por otro lado, un convertidor Buck es conectado a la salida del convertidor Boost, actuando como una fuente de corriente o tensión, dependiendo de la estrategia de carga que se implemente. Posteriormente, se presentan los resultados haciendo énfasis en el valor de 0.978 para el factor de potencia y el de 5.7% para el THD, el cual es comparado con el estándar IEC 61000-3-2. Finalmente, se evalúa la eficiencia del prototipo encontrando un valor máximo de 91.1% y luego se presentan las conclusiones.
Diseño e implementación de un sistema de fotolitografía para fabricar microdispositivos a partir de películas delgadas
Authors: Realpe Jhon Jairo , Bolaños-Pantoja Gilberto , Florez Juan Fernando
Published: June 2018

Este artículo presenta el diseño e implementación de un sistema de fotolitografía para fabricar microdispositivos basados en películas delgadas. El sistema trabaja con una fuente ultravioleta (UV) de 380nm y permite obtener microestructuras de 10-200 μm. La implementación se hizo con el proceso de diseño y desarrollo de productos, donde se determinó las especificaciones técnicas, generación, selección y prueba de conceptos de los módulos de equipo del sistema. Se implementó un spincoater con rango de operación de 500-6000 rpm y una fuente de radiación UV basada en LEDs UV, con potencia de radiación de 1-20mW/cm2 y tiempo de exposición de 1-60s. Se obtuvo micropuentes (mPs) de 30-105μm sobre películas delgadas de cobre. Con microscopía óptica y procesamiento digital de imágenes, se determinó que el error relativo porcentual en sus áreas es menor al 4% y la variabilidad en sus anchos es menor a dos veces la desviación estándar.
Construction of a short circuit frequency map to define GMAW-S parameters during WPSs development
Authors: Hoyos-Arango David Bernardo , Giraldo-Barrada Jorge Enrique , Mejía-López Oscar León
Published: June 2018

Se construyó un mapa de frecuencias para GMAW-S usando un aporte clase AWS ER70S-6 y gas de protección 75%Ar-25%CO2. Este tipo de mapa es una herramienta para seleccionar corrientes y voltajes de soldeo con proceso GMAW-S con mayor estabilidad. El mapa se construyó analizando señales de voltaje y amperaje registradas durante la aplicación de soldaduras a 5000 muestras por segundo. Se definieron regiones de operación sobre los mapas basados en resultados de inspección visual de soldaduras sobre platina y ubicando los límites de inestabilidad. Se analizaron dos ejemplos de parámetros de calificación de soldaduras usados industrialmente (corriente y voltaje) dibujando los límites establecidos por el código AWS D1.1:2015 para estas variables esenciales (±7% en voltaje y ±10% en amperaje del PQR) en el mapa de frecuencias. Se mostró como estos límites pueden contener regiones de baja estabilidad asociada al “stubbing” contra el metal base y al no reinicio del arco.