bluuebunny/crossref_metadata_2025 huggingface dataset:
Hyperpolarised129Xe magnetic resonance imaging to monitor treatment response in children with cystic fibrosis
Authors: Rayment Jonathan H. , Couch Marcus J. , McDonald Nancy , Kanhere Nikhil , Manson David , Santyr Giles , Ratjen Felix
Published: February 2019

Pulmonary magnetic resonance imaging using hyperpolarised129Xe gas (XeMRI) can quantify ventilation inhomogeneity by measuring the percentage of unventilated lung volume (ventilation defect per cent (VDP)). While previous studies have demonstrated its sensitivity for detecting early cystic fibrosis (CF) lung disease, the utility of XeMRI to monitor response to therapy in CF is unknown. The aim of this study was to assess the ability of XeMRI to capture treatment response in paediatric CF patients undergoing inpatient antibiotic treatment for a pulmonary exacerbation.

15 CF patients aged 8–18 years underwent XeMRI, spirometry, plethysmography and multiple-breath nitrogen washout at the beginning and end of inpatient treatment of a pulmonary exacerbation. VDP was calculated from XeMRI images obtained during a static breath hold using semi-automated k-means clustering and linear binning approaches.

XeMRI was well tolerated. VDP, lung clearance index and the forced expiratory volume in 1 s all improved with treatment; however, response was not uniform in individual patients. Of all outcome measures, VDP showed the largest relative improvement (−42.1%, 95% CI −52.1–−31.9%, p<0.0001).

These data support further investigation of XeMRI as a tool to capture treatment response in CF lung disease.
Effıcacy and safety of dapagliflozin on diabetic patients receiving high-doses of insulin
Authors: Sertbas Meltem , Sertbas Yasar , Okuroglu Nalan , Akyildiz Ali Burkan , Sancak Seda , Ozdemir Ali
Published: February 2019

Objective: In this study we aimed to investigate the efficacy and safety of dapagliflozin addition to diabetic patients using high dose insulin.

Methods: The current study was carried out in the outpatient diabetic clinics of Fatih Sultan Mehmet Education and Research Hospital. Thirty diabetic patients who were receiving high dose (>0.5U/kg) insulin and oral antidiabetic treatment (other than SGLT 2 inhibitors) were included in this study. Primary end point was the change in HbA1c, insulin doses and serum electrolyte from the addition of dapagliflozin 10 mg to the week 12.

Results: At the end of three month BMI were obviously decreased from 33.31±4.51 to 32.14±4.66 (p: 0.001). There was also an evident decrease of insulin requirement from 76±23.15 U/kg to 57.60±17.61 U/day (p<0.001). As well as the decrease in insulin doses, there was also a significant decline in HbA1c (Δ 1.6 %) and fasting blood glucose levels (Δ68.6 mg/dl) (p<0.001). Among serum electrolyte levels slight but meaningful increase of blood urea nitrogen (BUN) and sodium (Na) levels were seen (p: 0.044 and p: 0.026). There were no significant changes in serum cholesterol levels with electrolytes such as potassium, calcium, phosphorus magnesium and vitamin D (p>0.05).

Conclusion: In diabetic patients with inadequately controlled glucose regulation despite high-dose insulin therapy, dapagliflozin may be an alternative combination choice to decrease the need of insulin dose and obtain an optimal HbA1c, fasting plasma glucose levels and weight without major side effects.

How to cite this:Sertbas M, Sertbas Y, Okuroglu N, Akyildiz AB, Sancak S, Ozdemir A. Effıcacy and safety of dapagliflozin on diabetic patients receiving high-doses of insulin. Pak J Med Sci. 2019;35(2):399-403. doi: https://doi.org/10.12669/pjms.35.2.21

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
A novel ultrasound technique to detect early chronic kidney disease
Authors: Hewadikaram Dulitha K. , Bandara Mudhitha , Pattivedana Amal N. , Jayaweera Hiran H. E. , Jayananda Kithsiri M. , Madhavi W. A. Monica , Pallewatte Aruna , Jayasumana Channa , Siribaddana Sisira , Wansapura Janaka P.
Published: February 2019

Chronic kidney disease (CKD) of unknown etiology is recognized as a major public health challenge and a leading cause of morbidity and mortality in the dry zone in Sri Lanka. CKD is asymptomatic and are diagnosed only in late stages. Evidence points to strong correlation between progression of CKD and kidney fibrosis. Several biochemical markers of renal fibrosis have been associated with progression of CKD. However, no marker is able to predict CKD consistently and accurately before being detected with traditional clinical tests (serum creatinine, and cystatin C, urine albumin or protein, and ultrasound scanning).

In this paper, we hypothesize that fibrosis in the kidney, and therefore the severity of the disease, is reflected in the frequency spectrum of the scattered ultrasound from the kidney. We present a design of a simple ultrasound system, and a set of clinical and laboratory studies to identify spectral characteristics of the scattered ultrasound wave from the kidney that correlates with CKD. We believe that spectral parameters identified in these studies can be used to detect and stratify CKD at an earlier stage than what is possible with current markers of CKD.
Research and development of new tuberculosis vaccines: a review
Authors: Schrager Lewis K. , Harris Rebecca C. , Vekemans Johan
Published: February 2019

Tuberculosis kills more people worldwide than any other single infectious disease agent, a threat made more dire by the spread of drug-resistant strains ofMycobacterium tuberculosis (Mtb). Development of new vaccines capable of preventing TB disease and newMtbinfection are an essential component of the strategy to combat the TB epidemic. Accordingly, the WHO considers the development of new TB vaccines a major public health priority. In October 2017, the WHO convened a consultation with global leaders in the TB vaccine development field to emphasize the WHO commitment to this effort and to facilitate creative approaches to the discovery and development of TB vaccine candidates. This review summarizes the presentations at this consultation, updated with scientific literature references, and includes discussions of the public health need for a TB vaccine; the status of efforts to develop vaccines to replace or potentiate BCG in infants and develop new TB vaccines for adolescents and adults; strategies being employed to diversify vaccine platforms; and new animal models being developed to facilitate TB vaccine development. A perspective on the status of these efforts from the major funders and organizational contributors also is included. This presentation highlights the extraordinary progress being made to develop new TB vaccines and provided a clear picture of the exciting development pathways that are being explored.
Potential predictors of adoption of the Tobacco Heating System by U.S. adult smokers: An actual use study
Authors: Roulet Steve , Chrea Christelle , Kanitscheider Claudia , Kallischnigg Gerd , Magnani Pierpaolo , Weitkunat Rolf
Published: February 2019

Background: This was a pre-market actual use study with the Tobacco Heating System (THS), a candidate modified risk tobacco product, conducted with adult smokers in eight cities in the United States. The main goal of the study was to describe THS adoption in a real-world setting. The aim of this analysis was to identify potential predictors for adoption of THS using stepwise logistic regression method.

Methods: This actual use study was an observational study assessing self-reported stick-by-stick consumption of the THS product compared with the use of commercial cigarettes over six weeks. The study aimed at replicating the usage of THS in real-world conditions with participants being able to consume cigarettes, THS, and any other nicotine-containing products (e.g., e-cigarettes, cigars, etc.) ad libitum.

Results: 14.6% of participants adopted THS, which comprised 70% or more of their total tobacco consumption by the end of the observational period (in Week 6). The main predictors of adoption were the liking of the smell, taste, aftertaste, and ease of use of THS. The proportion of adoption was higher in participants aged 44 years and older and in Hispanic or Latino adult smokers. Additionally, adoption of THS was more likely in participants who had never attempted to quit smoking and in participants who smoked up to 10 cigarettes per day. Finally, the adoption of THS was higher in participants who consumed both regular and menthol THS compared with those who consumed only one THS variant.

Conclusions: The main predictors of THS adoption were positive sensory assessment and the ease of use. Socio-demographic characteristics and smoking habits appeared much less important. Post-marketing studies will provide further insights on the impact of the THS at the individual and the overall population level.
Relative Abundance of Transcripts (RATs): Identifying differential isoform abundance from RNA-seq
Authors: Froussios Kimon , Mourão Kira , Simpson Gordon , Barton Geoff , Schurch Nicholas
Published: February 2019

The biological importance of changes in RNA expression is reflected by the wide variety of tools available to characterise these changes from RNA-seq data. Several tools exist for detecting differential transcript isoform usage (DTU) from aligned or assembled RNA-seq data, but few exist for DTU detection from alignment-free RNA-seq quantifications. We present theRATs,an R package that identifies DTU transcriptome-wide directly from transcript abundance estimates.RATsis unique in applying bootstrapping to estimate the reliability of detected DTU events and shows good performance at all replication levels (median false positive fraction < 0.05). We compareRATsto two existing DTU tools,DRIM-Seq&SUPPA2,using two publicly available simulated RNA-seq datasets and a published human RNA-seq dataset, in which 248 genes have been previously identified as displaying significant DTU. RATs with default threshold values on the simulated Human data has a sensitivity of 0.55, a Matthews correlation coefficient of 0.71 and a false discovery rate (FDR) of 0.04, outperforming both other tools. Applying the same thresholds forSUPPA2results in a higher sensitivity (0.61) but poorer FDR performance (0.33). RATs and DRIM-seq use different methods for measuring DTU effect-sizes complicating the comparison of results between these tools, however, for a likelihood-ratio threshold of 30,DRIM-Seqhas similar FDR performance toRATs(0.06), but worse sensitivity (0.47). These differences persist for the simulated drosophila dataset. On the published human RNA-seq dataset the greatest agreement between the tools tested is 53%, observed betweenRATsandSUPPA2. The bootstrapping quality filter inRATsis responsible for removing the majority of DTU events called bySUPPA2that are not reported byRATs. All methods, including the previously published qRT-PCR of three of the 248 detected DTU events, were found to be sensitive to annotation differences between Ensembl v60 and v87.
Raising concerns – you and your colleagues
Authors: Bridges Glenys
Published: February 2019

Glenys Bridges considers the who, what, why, where and when

Aim

This article aims to enable dental nurses to: Recognise when a colleague's health, behaviour or professional performance is placing patients at risk, know when and how to raise concerns, and identify sources of guidance and support.

Objectives

On completion of this article, the reader will be able to: Act in line with fitness to practise guidance to maintain professional standards Follow practice policies and procedures for raising concerns Know when concerns should involve outside regulators.
The art of reflective practice
Authors: Sharma Priya
Published: February 2019

Priya Sharma considers this cornerstone of dental professional development
Dental care: the ‘bear’ essentials
Authors: Cassar Paul , Callaway-Goldstone Charlotte
Published: February 2019

Meet dentist Paul Cassar and dental nurse Charlotte Callaway-Goldstone, who are providing dental care to a very different kind of patient away from their high street practice…
Dental nurse-led sessions
Authors: Kaur Claire
Published: February 2019

Dental nurse Claire Kaur shares her experience
An impossible choice?
Authors: Wheeler Robert
Published: February 2019

Each month we take a close look at a recent legal case with implications for the surgical profession.
Isolation and molecular characterization of Mannheimia haemolytica and Pasteurella multocida associated with pneumonia of goats in Chhattisgarh
Authors: Rawat Nidhi , Gilhare Varsha Rani , Kushwaha Krishna Kumar , Hattimare Deeksha Dipak , Khan Foziya Farzeen , Shende Rajesh Kumar , Jolhe Dhananjay Kumar
Published: February 2019

Aim: The purpose of this study was to isolate and characterize the Mannheimia haemolytica and Pasteurella multocida from blood, nasal discharge, and lung tissue of pneumonic goats. Materials and Methods: A total of 14 goats were investigated for pneumonic pasteurellosis. Of 14 goats, nasal swabs and blood samples were collected from 10 clinically diseased animals. Moreover, lung tissue and heart blood samples were collected during necropsy of four goats died with pneumonia. All the samples were processed for the isolation of M. haemolytica and P. multocida in the laboratory. Bacterial isolates were identified by cultural and biochemical characters and 16S rRNA sequence analysis. All the isolates were subjected to susceptibility testing using commonly used antimicrobials. M. haemolytica isolates were characterized by PHSSA gene detection. P. multocida isolates were characterized by KMT1 gene detection and capsule typing. Results: On necropsy of dead goats, the pneumonia was characterized as acute fibrinous bronchopneumonia. Bacterial culture revealed the isolation of M. haemolytica (7) and P. multocida (5) of 10 clinical cases. Moreover, M. haemolytica and P. multocida were coisolated from two of the lung tissues. Furthermore, one of the other two lung tissues showed the isolation of M. haemolytica while the other showed recovery of P. multocida. Bacterial isolates were specifically identified by the 16S rRNA sequence analysis. The isolates showed reduced susceptibility to β-lactams, aminoglycosides, and fluoroquinolones . Moreover, the PHSSA and KMT1 genes were specifically detected among M. haemolytica, and P. multocida isolates, respectively. All P. multocida isolates belonged to serogroup A. Conclusion: The present study reported an occurrence of pneumonic pasteurellosis caused by M. haemolytica and P. multocida in a goat flock.
Acute Mediastinitis
Authors: Andriono Toto , Susanta I. G. N. , Makmuri Makmuri , Santosa Gunadi
Published: February 2019

Mediastiniti is not a new disease, however, the occurrence was rare especially in children. Focal infection which considered to be insignificant, can result in diffuse dissemmation involving mediastinum leading to fatal condition. This paper reported a case of mediastinitis with very critical condition. Fast and accurate diagnosis as well as adequate antibiotic treatment saved the patient without surgical intervention.
Paroxysmal Supraventricular Tachycardia in Children : The Role of Infectious Diseases and Its Relationship to Serum Enzyme
Authors: Wahab A. Samik
Published: February 2019

The records of 28 children whose first episode of paroxysmal supraventricular tachycardia occurred before 12 years (median age 10 months) were reviewed. There were 17 males and 11 females. In 17 cases the first attack occurred before the first year and in 11 of these it occurred after the first year. One case had congenital heart disease (ASD). The WPW syndrome was diagnosed in 3 cases. When first seen, most of the infants presented with signs of incipient or manifest congestive heart failure. In almost ninetenth fo cases rhere was an increased of serum enzymes (lactic dehydrogenase, creatinephosphokinase  and glutamic oxaloaccetic transaminase. Digitals was effective against congestive heart failure and when continued, might prevent failure during subsequent attacks. Antiarrhythmic agents other than digitals were not used. It is recommended to continue digitalis treatment for at least one year in all patients with SVT, whether or not the first episode terminated spontaneously.
Ventricular tachycardia in children with diphtheritic myocarditis
Authors: Wahab A. Samik
Published: February 2019

Nine children with diphtheritic ventricular tachycardia ranging in age from 2 to 11 years (mean 6.5 years) were observed and followed up until their terminal state. The ventricular tachycardia showed a left bundle branch block contour in 5 of 9 patients, right bundle branch block in four, multifocal pacemaker in three and unifocal in six patients. Fusion and captured beats were present in two and 4 patients respectively, Including one patient who had both. Four cases were without obvious atrio-ventricular dissociation.

All patients were treated with standard therapy for diphtheria, and prednison was given to patients with myocarditis. Because of its controversial results, antwrrhythm1c agent was not given.

The prognosis is very poor; all patients died one to 8 days after ventricular tachycardia appearance.
Infraspecific morphological variations of Salvia limbata in Iran
Authors: Talebi S.M. , Yadegari P. , Behzadpour S. , Matsyura A. V.
Published: February 2019

Salvia limbata is an aromatic herb of Lamiaceae, which distributed in different parts of Iran. Studies have revealed that this species has several benefit compounds for human health. In this study, we investigated infra‒specific morphological difference in this species. In total, 21 inflorescence morphological features were evaluated in eight populations; ten individuals were evaluated per each population. Data were analysed using SPSS and MVSP softwares. Morphological traits highly differed among the studied populations and ANOVA test revealed significant differences among most of them. According to UPGMA tree, PCA and PCO plots of morphological characteristics, we reported four distinct phenotypes among the studied populations. CA. Joined plot revealed each of these group were characterized by special traits, which were useful in identification of them. Two phenotypes were monotypic, while the rest were composed of two to four populations. This species has a relative large geographical distribution, the distribution of its populations in diverse area will prevent the focus of natural selection in a given direct. Therefore different phenotypes were found in its different populations.
Schools as market-based clusters: Geospatial and statistical analysis of charter schools in Ohio
Authors: Gilblom Elizabeth A. , Sang Hilla I.
Published: February 2019

This study contributes to the growing body of research concerning the strategic geographic positioning of traditional charter schools (TCS) in urban areas and their segregative effect by considering economist Michael Porter’s concept of business clusters, in which businesses ‘cluster’ to maximize their potential profit and to gain access to a customer base. Using a mixed-methods approach, we use geographic information systems (GIS) to perform an Average Nearest Neighbor Analyses (ANNA) to determine if charter and public schools (TPS) cluster in Ohio’s Cleveland Metropolitan School District (CMSD). We analyze school enrollment data and the local census tracts using MANOVA to compare the characteristics of TCS and TPS and produce maps of the results. Consistent with other research, we find evidence of increased segregation. The ANNA and MANOVA results indicate that TCS are more clustered than TPS and they tend to locate outside of the poorest communities with higher concentrations of Black and poor individuals.
Some pennies are more equal than others: Inequitable school facilities investment in San Antonio, Texas
Authors: Rivera Marialena D. , Lopez Sonia Rey
Published: February 2019

In Texas, local taxpayers fund the majority of educational facilities construction and maintenance costs, with local wealth influencing facilities outcomes. The traditional school districts that comprise the predominantly Latino and segregated San Antonio area vary considerably in property wealth as well as district capacity and expertise. We conducted an analysis of 12 San Antonio area school districts to address the questions: 1) To what extent do state and local investments vary by district? 2) How do district actions and constraints affect facilities quality and equitable investment? Methods include descriptive quantitative analysis of facilities investment data and qualitative interviews with school district leaders, staff, and school finance experts. Examining Texas school finance data demonstrated the variance in school district investments in educational facilities. Despite some districts with lower property wealth exerting higher levels of tax effort, they were able to raise less money per student for educational facilities through interest and sinking taxes. Interview findings revealed that several districts acknowledge lacking the capacity to maintain high-quality facilities for all students. Respondents frequently criticized current state policies and funding for educational facilities as inadequate, inequitable, and inefficient and expressed a need for policy improvements in an era of increasing state disinvestment.
Evaluasi Website ANRI (Arsip Nasional Republik Indonesia) Menggunakan Ten C’s
Authors: Krismayani Ika
Published: February 2019

Pembangunan suatu website tidak semata-mata berhenti setelah website tersebut dibangun. Namun, lebih dari itu, pembangunan suatu website dilakukan secara terus-menerus selama website tersebut masih tersedia, termasuk salah satunya adalah proses evaluasi website. Salah satu metode yang dapat digunakan dalam evaluasi website adalah Ten C’s. Hasil penggunaan Ten C’s terhadap website milik ANRI menunjukkan bahwa selain memiliki berbagai kelebihan seperti kelengkapan informasi, kejelasan visi dan misi, dan kebaruan informasi, website tersebut juga memiliki beberapa kelemahan. Kelemahan yang ada terkait dengan terlalu banyaknya konten yang ditampilkan, beberapa artikel tidak dilengkapi dengan penulis, dan konektivitas yang lambat pada jam-jam tertentu.
Literasi Media Pada Digital Native Kota Semarang
Authors: Rohmiyati Yuli
Published: February 2019

Tujuan dari penelitian ini adalah untuk mengetahui bagaimana peran orang tua dalam literasi media digital native. Metode penelitian yang digunakan adalah metode deskriptif. Peran Orang tua dalam mendampingi anak-anak digital native dalam menggunakan media/ ponsel dalam hal pengawasan, pembuatan kesepakatan2, dan pendampingan ttg materi apa saja yang diakses oleh anak-anak. Karakter-karakter yang muncul pada anak-anak digital native di Rusunawa Sawah Besar Kota Semarang menjadi bertanggung jawab, terbuka, komunikatif.
Peran Himpunan Mahasiswa dalam Pengembangan Koleksi di Perpustakaan Politeknik Negeri Semarang
Authors: Suwanto Sri Ati
Published: February 2019

Penelitian ini membahas mengenai Peran Himpunan Mahasiswa Divisi Perpustakaan dalam Pengembangan Koleksi di Perpustakaan Elektro Politeknik Negeri Semarang”. Tujuan Penelitian ini untuk mengetahui peran himpunan mahasiswa khususnya divisi perpustakaan dalam kegiatan pengembangan koleksi di Perpustakaan Elektro Politeknik Negeri Semarang. Metode penelitian yang digunakan pada penelitian ini adalah penelitian kualitatif dengan pendekatan deskriptif, jenis studi kasus. Pemilihan informan dalam penelitian ini menggunaka teknik pusposive sampling, yaitu dengan pertimbangan mahasiswa yang terlibat  dan melakukan  kegiatan pengembangan koleksi di Perpustakaan Elektro Politeknik Negeri Semarang serta mengetahui kegiatan Himpunan Mahasiswa. Teknik Pengumpulan data dilakukan dengan observasi, wawancara dan dokumen. Berdasarkan analisis data diketahui bahwa himpunan mahasiswa divisi perpustakaan sangat berperan dalam proses pengembangan koleksi di Perpustakaan Elektro Politeknik Negeri Semarang. Kegiatan yang dilakukan oleh divisi perpustakaan himpunan mahasiswa adalah menganalisis kebutuhan pengguna, melakukan kebijakan pengembangan koleksi, seleksi bahan pustaka, dan melakukan pengadaan. Kegiatan pengembangan koleksi dilakukan sebagai program kerja divisi perpustakaan himpunan mahasiswa.
Pengaruh Perilaku Asertif Pustakawan dalam Keberhasilan Program Liaison Librarian di Perpustakaan
Authors: Husna Jazimatul
Published: February 2019

Perpustakaan sebagai lokomotif ilmu pengetahuan, harus cermat menyikapi dan merespon perubahan tersebut dengan meyiapkan agenda-agenda yang relevan dengan kondisi kekinian dan trend perkembangan keilmuan kepustakawanan yang akan datang. Pustakawan yang dimaksud adalah pustakawan yang mempunyai perilaku asertif. Pustakawan yang mempunyai  perilaku asertif sangat berguna dalam berinteraksi dengan pengguna perpustakaan dalam mencarí informasi. Pemustaka yang tentunya memiliki kebutuhan informasi yang berbeda beda. Karena orientasi perpustakaan merupakan  kepuasan pengguna (user oriented). Program liaison librarian suatu program yang sangat menarik, dimana pustakawan harus secara aktif dapat memaksimalkan dalam  menjalin komunikasi dengan semua pengguna di perpustakaan, dapat melakukan diskusi dan harus menyediakan waktubisa memberikan konsultasi mengenai segala kebutuhan pemustaka terhadap kebutuhan informasi dan sumber-sumber informasi lainya.
SANMAI NO OFUDA DALAM PERSPEKTIF GREIMAS
Authors: Rahmah Yuliani
Published: February 2019

This paper entitled  Sanmai no Ofuda in Greimas’s perspective. Sanmai no ofuda is the title of Japan’s folktale has similarities with localfolktales from several regions in Indonesia. In this paper, the writer tried to explain the narrative structure of Sanmai no Ofuda in Greimas’s perspective.Its mean to reveal the narrative structure of this folktale,the writer used structural naratology approaches with Algirdas Julien Greimas’s theory. The writer tried to understand about the intrinsic elements  in Sanmai no Ofuda by examining the actans schemes and functional structure. The findings show that the narrative structure can explain  the intrinsic elements more specificly.
MENGENAL PROFIL KARAKTER BANGSA JEPANG MELALUI FILSAFAT GANBARU
Authors: Suseno Iriyanto Widi
Published: February 2019

The title of this research is to Know the Japanese Character Profile. The purpose of this study is to determine the role of Ganbaru philosophy in the formation of the character of the Japanese nation. The concept of ganbaru; survive, never give up, and do the best, which is implemented on the daily behavior of Japanese society. With descriptive research method of analysis, can describe the elements forming the character of the Japanese nation. This research can show that ganbaru philosophy has been practiced in many aspects of Japanese society life to bring the nation of Japan forward in world level.Key words : Profile of character, philosophy Ganbaru, Japanese nation
NOMINA BERPEMARKAH PARTIKEL O DALAM BAHASA JEPANG
Authors: Rosliana Lina
Published: February 2019

(Title: Noun Marked by Case Particle O in Japanese).   Noun in Japanese is a part of speech that can stand alone, not conjugated, and can occupy the function of the subject, object, as well as predicate in the sentence. Nomina can be named of goods, place name, person's name, profession, number, and others. This diversity makes the nouns in Japanese have different markers, one of which is the case particle o. Basically, case particle o in Japanese have a function as a marker of objects. However, the object function occupied by nouns is not just a target. Noun in Japanese can also be a word related to place or time. This study aims to examine the types of nouns marked by case particle o in Japanese. This research uses the method of distribution studies with agih techniques where the object is the language element studied. This study consists of three stages, namely data collection, data analysis, and data presentation. The data collected in the form of phrases with the construction of N + Po + V from various data sources online and print. The next step is to analyze the data collected by using the basic grouping of nouns from Moriyama (2008). The data that have been analyzed will be presented in descriptive form.Keywords : Noun, Case Particle o, Japanese
PERGESERAN MAKNA DALAM CERPEN HACHI NO JI YAMA
Authors: Rahmah Yuliani
Published: February 2019

(Title: Meaning Shift in Japanese Short Story “Hachi No Ji Yama”) A literary work will be translated properly according to the original text if an interpreter does the translation procedure appropriately. The translation procedure itself is divided into 14 types, but in the translation process from Japanese into Indonesian, there are three types which commonly used in procedures of the translation process.  It is  Transposition, Modulation, and Adaptation. This paper tried to explain the use of that three types of translation procedures in a Japanese short story. The short story used as the object of this paper was a children's short story entitled Hachi no Ji Yama by Tsuchida Kohei. Referring to the translation rules, the results are that the Hachi no Ji Yama short story uses 2 translation procedures, which is transposition and modulation. With the differences in the rules of language and grammatical structure between Indonesian and Japanese, the most widely used of transposition procedures are the first and second types, while the modulation used is free modulation.
Anthropocene-Bio-geography need reverse Gearing in India: Beyond Domestication and Farming
Authors: Mishra Siba Prasad , Mishra Durga Prasad
Published: February 2019

The plate boundaries are the limits of the faunal biodiversity. The species can be endemic, converging or invasive. International Union for Conservation of Nature and Zoological Survey of India are the agencies record and make an action plan
to preserve extant/extinct and endangered species. India has 2.4% of the landmass of the globe but accommodating about 7-8% of the total species of the world so a rich biodiversity nation. The country lies at the confluence of the Central zone of
Africa, Europe and Malaya region, the biota therefore includes African, European, Eurasian and Mediterranean geographical areas, India has a unique assemblage of flora, fauna, avifauna and aquafauna along with some endemic species, that contributes
to the richness of the nation. India’s biodiversity population changes are influenced by climate, temperature, altitude, invasive alien species, topography, moisture, CO2, light, nutrients, water quality, ambient air, habitation, and above all the
anthropogenic activities for their growth, survival, or reproduction. Present study envisages preparation of an updated bio-geographical status of the species, statistical analysis of the biota those are endangered and threatened and causes for such
defaunation and defloration. Though preservation action plans have been enhanced in India through biodiversity reserves yet it is observed that the largely under-explored sector is algae, protists, fungi, microbes. The biodiversity in the marine
sector is given less importance for conservation in India
Analysis of Tools used in Friction Stir Welding process
Authors: Mishra Akshansh , Tiwari Adarsh , Shukla Mayank Kumar , Rose A. Razal
Published: February 2019

A relatively new joining process, friction stir welding (FSW) produces no fumes; uses no filler material; and can join aluminium alloys, copper, magnesium, zinc, steels, and titanium. FSW sometimes produces a weld that is stronger than the
base material. The tool geometry plays a critical role in material flow and governs the transverse rate at which FSW can be conducted. The tool serves three primary functions, i.e., (a) heating of the work piece, (b) movement of material to produce
the joint, and (c) containment of the hot metal beneath the tool shoulder. Heating is created within the work piece by friction between both the rotating tool pin and shoulder and by severe plastic deformation of the work.
Removal of heavy metals using kaolinite and Bentonite filter media
Authors: Heikal Ghada
Published: February 2019

Heavy metals are among the most lethal pollutants of surface water. The main sources of heavy metals are industrial wastes from processes such as mining operations and ore processing, smelter, textile, leather dyeing, coating, metal
finishing, chemical manufacturing, refineries, power generation and nuclear fuel processing. The concentration of heavy metals should be reduced to the acceptable levels before discharged into the environment because these are non degradable into
nontoxic metals end products and the well known damaging effects of heavy metals on human being and other habitants. Sets of experiments were carried out to examine the ability of (kaolinite and bentonite) to reduce the concentration of chromium and
cadmium ions in raw synthetic wastewater using upflow filter respectively. The main parameters were solution pH 2-6, retention time 12-72 hrs, the initial concentration of pollutants 100–500 ppm and filter media height 10.5-42 cm. All data were
analyzed by regression analysis model to correlate the different boundary conditions. The highest achieved % removal efficiency of Cr and Cd were 96% and 91% through kaolinite and bentonite clay filter media at pH 6.0 and 5.0 respectively, retention
time 24 hr, initial concentration 100 ppm and filter media height 42 cm. The results of regression models indicate that the most influential independent variables in the % removal efficiency of Cr and Cd ions from aqueous solutions using kaolinite
and bentonite clay upflow filter pH, retention time and height media filter, which affects positively. Results of the experimental data show that the best empirical correlation achieved the highest fitting of predicted % removal of Cr and Cd using
kaolinite and bentonite clay separately that gives the highest value of (R2 = 0.995 and 0.988)respectively.
Investigating the Behavior of Low Permeable Lean and Rich Gas Condensate Reservoirs
Authors: Nawab Sohail , Tunio Abdul Haque , Mahesar Aftab Ahmed , Hullio Imran Ahmed
Published: February 2019

The producing behavior of low permeable gas condensate reservoirs is dramatically different from that of conventional reservoirs and requires a new paradigm to understand and interpret it. As the reservoir pressure initiates to decline and
reaches to dew point pressure of the fluid then the condensate is formed and causes the restriction in the flow in the reservoir rock which results, decrease in the well productivity near the wellbore vicinity which is known as condensate blockage.
Henceforward, it is better to understand the behavior of the low permeable lean and rich gas condensate reservoirs by several perspectives through the compositional simulator. Besides this study involves the following perspectives; the increase in
the number of wells and by varying the flowrate of the gas in six different cases for low permeable lean and rich gas condensate reservoirs. It was concluded that low permeable lean and rich gas condensate reservoirs have similar gas recovery
factors. Whereas the CRF plays inverse behavior for both reservoirs as CRF is maximum for lean gas condensate at single producing well but for rich gas condensate reservoir the CRF increases as the number of wells escalates. Additionally, in second
effect the varying gas flowrates lean gas condensate reservoir has maximum CRF at lesser flowrate but it is opposite for the low permeable rich gas condensate reservoir, for single or two producing wells the flowrate effect plays but when the number
of wells is increasing there is not any significant change in CRF
Design and Economic Evaluation of the ESP and Gas Lift on the Dead Oil Well
Authors: Hullio Imran A. , Jokhio Sarfraz A. , Memon Khalil Rehman , Nawab Sohail , Baloch Khair Jan
Published: February 2019

Owing to the increasing water cut and decreasing in reservoir pressure of the well, the oil production of the well has seized and the well has become dead. This research study evaluates the implementation of the artificial lift methods ESP
and Gas Lift- economically and technically on the well by using the production performance software (PROSPER) and economical yardsticks (NPV and ROI). The theory, design, production forecast, capital and operating expenditures of the electric
submersible pump and gas lift are discussed for the appropriate selection of any of two options. The PROSPER software is used as the simulation tool for the design and production forecasting of the ESP and Gas Lift based. The ESP and Gas Lift methods
have been simulated for the design and production forecast by entering the reservoir and completion inputs in the software. Subsequently, the software has been simulated to run on different sensitivities of the variables such as water cut, wellhead
pressure setting depth, operating frequency and gas injection rates to check the production rates at different scenarios. Having performed the production performance simulation on the selected artificial lift methods, the methods have been
investigated by capital budget-ing. In capital budgeting, the capital and operating expenditures of both lift methods were evaluated by determining their discounted value (NPV) and re-turn on investment (ROI). The prime objective of the research is
to accomplish maximum production rates and profitability by selecting the most appropriate artificial lift method for the well; as a consequence it is concluded that the suitable artificial lift method for a well can be selected by applying the
simulation and economical schemes.
Response of Multistory Irregular L Shape Building under Basic Wind Speed of 39 m/s
Authors: Jamle Sagar , Sadh Ashish , Pal Ankit
Published: February 2019

Wind analysis in this era considered as a main criteria for modern tall buildings such that the tall buildings are considered as a cantilever structure which is fixed at its base and is free at other end. These multistory buildings are not
same in plan and having different projections which is vulnerable to wind and its exposures. The main criteria in this research work is to present the position of these tall buildings having plan of L – shape 20 story building under a basic wind
speed of 39 m/s. Using Staad pro software, a total of 4 cases has analyzed. Dimension of plan is different from both the projection on which wind is applied in all four directions. A comparison of result parameters like displacements, story drift,
axial forces in column, shear in beam in both longitudinal and transverse direction are made for all the models and suggestions are made to choose which position is the best of all.
A Speed Based Congestion Study of a Road Section Connecting Fulbarigate-Dakbangla, Khulna
Authors: Das Palash Chandra , Bintee Neeti Zaman , Azad A. K.
Published: February 2019

Congestion, a problem that is not new for a third world country like Bangladesh. Like the other megacities of Bangladesh, Khulna is gradually experiencing this phenomenon in an acute manner. Khulna-Jessore highway that runs through the city
and gives it a linear form works as the backbone of the traffic skeleton of Khulna city. This study focuses on developing a speed based model for predicting congestion scenario of Khulna city. Fulbarigate to Dakbangla midblock is chosen as the study
corridor. The whole study corridor (10.73km) is divided into two equal halves and travelled 10 times with the stream and against the stream to generate 20 data set. Speedometer GPS survey along with moving observed method is used to collect necessary
data. A latitude longitude based speed profile is found at each travel based on which travel speed index (TSI) is calculated and a multiple linear regression (MLR) model for predicting congestion is developed. Independent variables are selected based
on the possibility of affecting congestion of the road section. The MLR model is found as TSI = 0.0167083 + 0.0001826*Volume (PCU/hr.) + 0.0019625*Speed Drop Factor, with 8.86 % error. Congestion is found severe at Doulatpur Bazar and Shibbari to
Dakbangla circle within the study corridor. Due to illegal parking spot, road capacity is not utilizing properly. As a result in peak hour, speed drops more than average peak hour speed and congestion occurs.
Character Education Through Dola Bololo in Early Childhood at Afe Taduma Ternate North Maluku, Indonesia.
Authors: Said Sida , . Yufiarti , Sumantri Moch.Syarief
Published: February 2019

The purpose of this article is to know the character education through Dola Bololo can give to early childhood, place,and time Dola Bololo is expressed to educate characters in early childhood in Afe Taduma Ternate. This study used
ethnography qualitative methods to determine character education through Dola Bololo individually or in groups. The results show that character education can be provided through Dola Bololo for the formation of early childhood characteristics such as
religious education, mutual assistance, togetherness, love of the nation, caring for nature. The Character education can be given at home, school and the environment. Dola Bololo is pronounced in poetry, syarhil, and sung at certain times.
Impact of truck art, as popular culture on Pakistani society
Authors: Sheikh Samina Zia
Published: February 2019

Several theories directly deal with popular culture rather mass media, though; they both are closely knitted now. Popular culture in Pakistan is well portrayed through moving canvases on roads in form of trucks that also play equal role as
mobile billboards. Meanings that from popular culture are taken are well interpreted as available artefacts, films, cloths, records, Television programs, as well as modes of transport. Classification of unlimited that man experiences, sees or takes
information from does not have a strict or exclusive definition. Beliefs, practices, traditions, taboos, kinetics, different objects are all essentials of every culture. Truck art as popular culture in Pakistan brings forth an assortment of
experiences, expressions, feelings, perceptions, ideologies, faiths through harmonized amalgamation of images, writings as well as three dimensional embellishments and leaves enormous impact on community. Focus of this study is to interpret
frequently seen metaphors that have allegoric, emblematic, historic or contemporary significance the way they are communicated through visuals. This study highlights an extensive introduction of an extraordinary art which is an outstanding
amalgamation of art and crafts in form of ornamentation and embellishment of heavy vehicles. It also covers the styles and materials used in ornamentation and philosophy that is adopted in various patent schemes and objects. Truck art, as popular
culture is an attempt to examine and unlock deeper significance of metaphors that are accepted by people in dissimilar ways. Analysis of frequently conveyed messages through skilfully employed epigraphy and poetic interpretations leave ironic effect
and make it more fun than its aesthetic value. Such interpretations enable one to become detective with most interesting analysis of cultural beliefs, taboos, traditions and values. Unquestionably truck art as popular culture plays an active role in
communication and is a strong medium of expression.
Influence of Physical Engagement on Job Performance among Employees in the Civil Service: A Case of Kakamega Regional Head Quarters in Kenya
Authors: Nyikuli Eshiteti Stephen , Makhanu Roselyne , Mukanzi Dr. Clive
Published: February 2019

The purpose of this study was to investigate the influence of physical engagement on Job Performance among employees in the civil service at Kakamega regional Headquarters, Kenya. A target sample of 258 respondents drawn from a sampling
comprising top, supervisory, and lower cadre employees was obtained using stratified and simple random sampling techniques. From the top management, a census was used to obtain all the 30 respondents. From the supervisory and lower cadre employees’
strata, a proportionate allocation was used to select a 61 middle managers and 167 lower cadre employees (representative sample from each) and the data collected by use of questionnaires. Data was analysed using descriptive, correlation and multiple
linear regression analyses. Findings of the study indicated that the civil service employees at Kakamega regional Headquarters experience high physical engagement from their superiors. As a results, it was found that their job performance had
increased considerably. Further, the study also revealed a strong positive and significant correlation between physical engagement and job performance. These findings suggest that the civil service employees value the physical engagement that they
receive from their workplaces which then leads to increased job performance. Therefore, the study recommends that more emphasis should be placed in ensuring the civil servants at Kakamega regional headquarters continue to be more physically engaged
for enhanced job performance.
Rainwater Resources Development using Open Space data and Software Sources
Authors: Mohamed Gar Al-nabi Ibrahim , Althobiani Faisal
Published: February 2019

Humans and animals drinking water availability is a chronic problem in under-developed countries in general and their rural areas in particular. A rainwater resources development effort was reported in this paper using a case study area in
the Sudan. A rainwater harvesting method was developed using open space technology data and open application programs. The method was applied in a 12,100 square kilometers area and twenty-two potential rainwater harvesting sites were located with
draining capacities ranging between 19.10 and 532.50 Million Cubic Meters (MCM) with a total average rainfall rate draining capacity of 2.105 Billion Cubic Meter (BCM). However, although it is quite possible to acquire this huge amount of water in
the area, but unfortunately, local people are still facing a chronic problem of drinking water shortage, animals walk tens of kilometers to drink water and farmers transport water from the Blue Nile river tens of kilometers away from the farms to
harvest their crops. An appreciated effort was made by local governments and non-government organizations related to drinking water world wide in general and in underdeveloped countries in particular using traditional methods. However, it is high
time to devote this effort to the application of open space technology data and open application programs for water harvesting in these areas. This would facilitate the water supply throughout the year and avoid the drinking water shortage in the dry
season. It can be applied to cover the whole area with a network of water harvesting facilities to achieve nomad’s and pastoralists settlement, avoid their conflicts with farmers in the area.