bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of oxidative stress biomarkers and liver enzyme activity in workers occupationally exposed to respirable free crystalline silica
Authors: Poormohammadi Ali , Talebi Ghane Elaheh , Mir Moeini Effat Sadat , Bashirian Saeed , Motavallihaghi Seyedmousa , Mehri Fereshteh
Published: February 2023

Introduction: In various mining activities, workers   are   exposed   to free Crystalline Silica (CS), which can cause the constant production of reactive oxygen species and silicosis. This research was conducted to evaluate oxidative stress biomarkers and liver tissue function in workers occupationally exposed to CS during their activities.
Materials and methods: In this study, the biomarkers of oxidative stress were evaluated in 40 workers in silica mines of Azandarian region (Hamadan province, Iran) with occupational exposure to CS, as the case group and 40 workers without any silica-exposure as controls.
Results: A significant higher serum levels of Malondialdehyde (MDA), Reactive Oxygen Species (ROS) and Alanine Transaminase (ALT) were observed in the silica-exposed group compared to the controls. Moreover, in the serum of the silica-exposed cases, the total antioxidant capacity was lower than that of the control group. Based on findings chronic exposure to CS can obviously affect the serum levels of oxidative stress biomarker and liver tissue function in the exposed workers.
Conclusion: Therefore, the use of suitable face mask and different dietary antioxidants are recommended in the silica-exposed workers for the reduction of oxidative stress production and prevention of liver tissue disorders.
Immersive Visualization of Python Coding Using Virtual Reality
Authors: Saleh Abdulrazak Yahya , Chin Goh Suk , Othman Mohd Kamal , Mohamad Fitri Suraya , Chen Chwen Jen
Published: February 2023

The main goal of this study is to develop a mobile Virtual Reality (VR) application to conduct basic Python coding skills for university students who are struggling to learn to code. This study employs a quasi-experimental method to examine the difference in the efficiency of VR and traditional learning methods by evaluating the students' performance. Thirty students between 18 to 22 years old participated. The participants were divided into two control groups, in which one group used the conventional python learning method while another implemented the VR application in python learning. Unity 3D was used as the application development tool with Mobile Application Development Lifecycle (MADLC). The developed VR application was employed using Google cardboard to create an immersive VR experience. Usability tests, hypothesis tests, Presence Questionnaires (PQ) and system usability scale (SUS) are used as evaluation tools. Findings illustrated how learning through VR has yielded better performance than the conventional learning method. In hypothesis testing, the VR learning method suggested more effective learning with t_statistic value of 4.992, a more considerable value than t_critical=2.76. 73% of the participants rated above 68 out of 100, which indicated high levels of satisfaction with the use of the mobile VR application to learn Python. In short, the VR method is perceived to be useful and convenient to help students learn at any place and time.
Effect of Combination Shunt Passive Filter Harmonic and Detuned Reactor on the K-Factor Changes of Transformer
Authors: Gumilar Langlang , Afandi Arif Nur , Aripriharta - , Habibi Muhammad Afnan , Kusumawardana Arya
Published: February 2023

This paper describes the impact of changes in harmonic distortion on the value of the transformer K-Factor. The transformer has a capacity of 1.5 MVA and a K-Factor value of 1 under normal conditions. Techniques were installed to reduce harmonic distortion, shunt passive filter, and detuned reactor. Several condition scenarios were created to compare changes in harmonic distortion's value to the K-factors value. Scenario 1, the transformer works in harmonic conditions. The K-factor value of the transformer becomes 3.947101, and the new capacity of the transformer that can serve the load becomes 1.27 MVA. Scenario 2, a passive shunt filter was installed in the transformer circuit. Shunt passive filter can reduce IHD-V and THD-V values on PCC but increase IHD-I and THD-I values on the load side. The k-factor value fell to 1.5775, and the new capacity of the transformer increased to 1.44 MVA. The novelty of this paper is in scenario 3, a combination of a passive shunt filter and a detuned reactor was installed in the transformer circuit. The detuned reactor can limit the harmonic current that enters the harmonic filter. As a result, all values, including IHD-V, THD-V, IHD-I, and THD-I fell below the maximum harmonic distortion limit. The k-factor value fell to 1.0361, and the new capacity of the transformer increased to 1.49 MVA. The existence of a detuned reactor has been able to increase the performance of the passive shunt filter. The impact of the detuned reactor for future research is that it can be used to protect important equipment in the electric power system.
Generation of Batik Patterns Using Generative Adversarial Network with Content Loss Weighting
Authors: Minarno Agus Eko , Antoko Toton Dwi , Azhar Yufis
Published: February 2023

Every craftsman who draws Batik can also not necessarily draw various types of Batik. On the other hand, it takes a long time ranging from weeks to months, to make Batik. Image generation is regarded as an essential part of the field of computer vision. One of the popular methods includes the Generative Adversarial Network, commonly implemented to generate a new data set from an existing one. One model of the Generative Adversarial Network is BatikGAN SL generating batik images by inserting the two Batik patterns to produce a new Batik image. Currently, the generated Batik image does not maintain the input of the Batik pattern. Therefore, this study proposes a GAN model of BatikGAN SL, with the addition of a content loss function using hyperparameters to weight the content loss function. The content loss function is added from the Neural Transfer Style method. Previously, the style loss function in this method has been implemented in BatikGAN SL, and the dataset consists of Batik patches (326 images) and real Batik (163 images). This paper compares the BatikGAN SL model from previous studies with the BatikGAN SL model by implementing hyperparameters on the content loss function. The evaluation is conducted with FID, containing FID Local and FID Global. The results obtained in this study include a collection of Batik images, test evaluation value of 42 on FID Global and 16 on FID Local. These results are obtained by implementing the content loss function with a weight value of 1.
Structure-Based Design of Recombinant Spike Subunit Vaccine for Coronavirus Diseases
Authors: Mahmuda Mahmuda , Al Jannah Shofi , Fibriani Azzania , Ningrum Ratih Asmana , Wardiana Andri
Published: February 2023

The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is still surging across the globe and has affected serious problems for both health and the global economy; therefore, the development of a vaccine with good efficacy becomes a must. To tackle the pandemic, numerous sectors of academia, industry, and the government collaborate to develop and investigate potential vaccine platforms. The recombinant subunit vaccine is one of the safest types of vaccine. However, its development has lagged behind other platforms, owing to the need for greater antigen manufacturability and immunogenicity. In this review, we outline several protein engineering strategies carried out in developing the recombinant COVID-19 vaccine, including the fusion of antigens with Fc fragment of human IgG, carrier proteins, trimerization domains, and stabilizing mutations. A systematic literature review was performed to summarize key takeaways from studies on developing recombinant subunit vaccines of SARS-CoV, MERS-CoV, and SARS-CoV-2, highlighting vaccine design and expression system, antigen structure, and in vivo and in vitro results of each protein engineering strategy. Several protein engineering strategies, particularly S protein and RBD, can improve the antigen's stability, manufacturability, and immunogenicity. Finally, novel protein engineering strategies are expected to be further developed to increase the vaccines' overall manufacturing, and the current recombinant vaccine candidates will be further processed into clinical stages to confirm their efficacy against pathogenic human coronaviruses.
A Comparative Analysis of External Lightning Strike Protection Area Determined by Using Protection Angle and Rolling Sphere Methods
Authors: Putri Anisa Erma , Warmi Yusreni , Nur Putra Andi M , Zulkarnaini -
Published: February 2023

The lightning phenomenon is a natural disaster that endangers human life. The nature of grabbing objects closest to the cloud can cause fires, damage to electrical equipment, and even fatalities. The Padang Institute of Technology is a campus that has tall buildings, such as buildings B, C, D, E, and F, without an adequate lightning protection system. This is certainly a concern regarding security and safety for building users on the ITP campus. This research was conducted to reduce the risk of being hit by a lightning strike on the ITP campus. The protection system design process refers to the IEC 62305-3 standard comparing the protection angle and rolling sphere methods. Meanwhile, the procedure for calculating building requirements for a protection system or building protection level refers to the PUIPP and IEC 1024-1-1 standards. After analyzing the lightning rods in 5 ITP campus buildings by comparing the protection angle and rolling sphere methods, it can be concluded that there are still parts of the building that are not protected by the size of the installed air terminal. To overcome this, adding or adjusting the air terminal level is necessary so that all buildings are in the protection area. In addition, in conducting the analysis, the method considered the best to provide clear information on the part of the building that needs protection and the amount of the building that has been protected is the Rolling sphere method.
Expression of a Synthetic Staphylococcal Enterotoxin B in Escherichia coli BL21(DE3) for Cancer Therapy Development
Authors: Rodiansyah Achmad , Tan Marselina Irasonia , Nugrahapraja Husna
Published: February 2023

Staphylococcal enterotoxin B (SEB) from Staphylococcus aureus is a potential therapeutic agent for cancer. SEB can activate the immune response, which could induce apoptosis of various cancer cells. This study aimed to design and produce a recombinant SEB protein using Escherichia coli BL21(DE3) expression system. We designed and optimized the codon of the inserted gene for E. coli and then transformed it into E. coli BL21(DE3). The transformants were verified by selective media containing kanamycin followed by colony PCR with T7 promoter and T7 terminator primers and DNA sequencing. The results showed that the SEBsyn encoding gene could be synthesized and cloned into pET-28a(+) expression plasmid. This recombinant plasmid that carried the SEB encoding gene (pET-28a_SEBsyn) was successfully transformed into E. coli BL21(DE3). The amplicons of colony PCR visualized in 2% agarose gel showed that transformants carrying the recombinant plasmid had an inserted gene length of about 1 kb. Gene inserts sequence verification by DNA sequencing resulted in 1,148 bp sequence consensus. The blastx analysis showed that it had the best hit with enterotoxin B in the NCBI database (accession id CAC6284025.1). The recombinant SEB protein was also successfully overexpressed in E. coli BL21(DE3) with 0.1 mM IPTG. Our recombinant SEB protein was dominantly insoluble in the inclusion body; however, some SEB protein was expressed as soluble. The molecular weight of the target protein is about 29 kDa.
Determination of Total Carotene and Vitamin C in Chili Powder (Capsicum annuum L.) Non-destructively Using Near-Infrared Spectroscopy
Authors: Khuriyati Nafis , Sukartiko Anggoro Cahyo , Falah Moh Affan Fajar , Alfiani Ririn Nur
Published: February 2023

Chili (Capsicum annuum L.) is an important source of total carotene and vitamin C. Both substances are widely used in food processing materials, supporting a healthy immune system and medicine. However, destructive testing often obtains information about the substances, which damages the tested material and requires a relatively long analysis. Therefore, this research aims to develop calibration models of total carotene and vitamin C in chili powder for non-destructive testing using near-infrared spectroscopy. The samples consist of four groups of color, i.e., light green, dark green, red tinge, and red, with a total of 84 samples. Seventy percent of the sample was used for calibration, while the rest of the sample was used for validation. Spectra were measured using the NIRFlex N-500 instrument at a wavelength of 1000 nm to 2500 nm and analyzed with the partial least square (PLS) method using three spectral pre-treatments, which are multiplicative scatter correction (MSC), first derivative savitzky-golay, and de-trending. The accuracy and model reliability was determined by the coefficient of determination (R2) and the residual predictive deviation (RPD). The best calibration models were successfully obtained when the spectrum was processed using the first derivative savitzky-golay pre-treatment with 6 and 5 PLS factors for vitamin C and total carotene, respectively. Both models were accurate and can be potentially used for determining the total carotene and vitamin C in chili powder samples non-destructively.
Activated Carbon from Palmyra Palm Peel as an Alternative Adsorbent for Removing Heavy Metal Ions Fe(III) and Cr(VI) in Industrial Waste
Authors: Prastuti Okky Putri , Kurniati Yuni , Septiani Eka Lutfi , Pratiwi Nadia Fatimah , Ardiansyah Mukhammad Pascal , Ismadji Suryadi , Yuliana Maria , Martak Fahima
Published: February 2023

Palmyra palm peel served as raw material for preparing activated carbon. In addition to its high cellulose content, palmyra palm shells are also easily found in Gresik and Tuban, East Java. Palmyra palm shell is also an abundant solid waste with low economic value, so using palmyra palm shells as raw material for activated carbon production is low cost to reduce the contaminant in liquid waste. This experiment aims to determine the effectiveness of palmyra palm peel as a bio-adsorbent for heavy metal ions Fe(III) and Cr(VI) in industrial waste. This research was conducted through 3 processes: chemical activation, carbonization, and adsorption. The methods used in this study consisted of pre-treatment, activation of raw materials, manufacture of standard solutions, calibration of standard solutions, and adsorption of heavy metals from textile waste. The carbons' activation was conducted at 600 and 700oC in the presence of KOH as the activating agent. The results are a water content of 17.50% and an ash content of 8.37%. The moisture content and ash produced results comply with the SII and SNI 06-3730-1995 standards. The carbon produced at 700oC has a better adsorption performance than that produced at 600oC. The maximum removal efficiency for Fe(III) was 95.25, and Cr(VI) was 89.7%. Two well-known equations, Langmuir and Freundlich, were used to correlate the experimental adsorption data. Langmuir equation could represent the data better than Freundlich with an R2 value close to unity.
Indigenous Knowledge of Peanut Cultivation of the Ethnic Khmer Resident in the Mountainous Area in An Giang Province, Vietnam
Authors: Phung Bui Thi Mai , Hoa Nguyen Van , Phong Le Thanh , Nhan Tanh Nguyen Tran , Chiem Nguyen Huu
Published: February 2023

Indigenous knowledge (IK) can provide useful information on local people's activities within environmental contexts. For countries vulnerable to climate change as Vietnam, research on IK might assist in revealing information about local people's responses to environmental stresses and potentially support decision-making. To enrich the study context in this field, this study aims at determining the IK of peanut cultivation of the Khmer ethnic groups. The study site is in the mountainous area in An Giang province, Vietnam, where the Khmer people are located. The methods of documentary collection, focus group discussion, semi-structured interviews, and experiments were applied in this study. The investigation results showed the innovation of local people in the cultivation. For instance, applying cow manure to a sandy soil can reduce chemical fertilizers and improve peanut yield. The IK reported that the application of the broadcasting method could achieve the cultivation economic profit approximately 2.5 times higher than the dibbling method. The former method is mostly preferred due to its time/labor saving and the growing aged population in the study location. The experimental results indicated that the combination of indigenous and scientific knowledge in peanut cultivation, such as chemical fertilizer application, crop calendar, crop rotation, and varieties, could bring high economic efficiency, improve soil nutrients, and ability to adapt to climate change. The research approaches in this study comprehensively revealed the IK, which can be potentially applicable to similar studies.
Application of Analytical Hierarchy Process (AHP) in Determining the Development Strategy of Tempeh Processed Product
Authors: Harisudin Mohamad , Adi R. Kunto , Qonita Rr Aulia
Published: February 2023

This study aims to determine the criteria and best strategies for developing new products processed tempeh in Surakarta City. The research design used is descriptive-analytical by basing data from key informants through in-depth interviews combined with focus group discussions. The collected data is compiled, analyzed, and discussed to illustrate the reality of tempeh-processed SMEs in the field. Aggregation techniques for making conclusions from diverse information using source triangulation. While analytical tools determine strategic priorities using the analytical hierarchy process (AHP). The study results obtained six criteria for developing new products for processed tempeh. These criteria are market demand, risk of production failure, tempeh processed technology that has been mastered, waste handling, absorbing labor, and profits. In contrast, the alternative strategies that are successfully formulated based on the SWOT matrix consist of three alternative strategies: product differentiation, improving product quality and packaging, and the legality of products supported by digital marketing. Based on AHP obtained, the most important criterion is profit. In contrast, the priority strategy for developing processed tempeh products is to improve the product's quality and packaging. This study provides helpful information in solving the problem of SMEs in determining the priorities of various alternatives faced by SMEs. AHP-based analysis can overcome the weakness of SMEs who do not orderly document quantitative data because AHP can process both quantitative and qualitative data.
Urban Farming Development Strategy to Achieve Sustainable Agriculture in Magelang, Indonesia
Authors: Nugroho Reismaya Wanamertan , Kusnandar - , Sutrisno Joko
Published: February 2023

The population growth every year causes an increase in land demand. This has led to conversion from agricultural land to non-agricultural land, especially in urban areas where people in rural areas migrate to cities, one of them is Magelang. The agricultural land decrease and impacts less production. The concept of urban farming provides a solution for urban areas to maintain agricultural production by utilizing residents' yard. On the other hand, urban farming practices must still pay attention to agricultural sustainability, so they are maintained in the future. This study aims to determine the priority of urban farming development strategy in Magelang by using criteria in the dimension of sustainability. This study used the Analytical Network Process (ANP) method by involving several expert respondents in conducting the assessment. Based on the analysis results, the sustainability dimension's priority is the social dimension. Meanwhile, the priorities in each economic, ecological, social, technological, and institutional dimensions are income of women farmers group members, land availability, motivation of women farmers group members, cultivation technology, and the role of agricultural extension. Based on the criteria in the dimension of sustainability, the priority of Magelang's urban farming development strategy is integrated agriculture. The results of this study can be used as a reference for further research on the development of urban farming through integrated agriculture.
Transaminase Enzyme Activity and Histopathology Evaluation of Ratâ€™s Liver Induced by DMBA with Temulawak Extract (Curcuma xanthorrhiza)
Authors: Hasan Akhmad Endang Zainal , Falah Syamsul , Handharyani Ekowati , Dwicesaria Maheswari Alfira
Published: February 2023

Temulawak rhizome (Curcuma xanthorrhiza) contains curcumin and xanthorrhizol, which may be used as breast cancer drugs and hepatoprotection. This study aims to analyze the activity of alanine and aspartate transaminase enzymes and the histopathological picture of 7,12-Dimethylbenz(Î±)anthracene (DMBA)-induced rat liver due to the administration of temulawak extract. This study used 28 female white rats, divided into seven treatment groups, a control group (normal and DMBA) and a treatment group induced by temulawak extract orally with doses of 35, 70, 140, 210, and 280 mg/kg Body Weight (BW) during the 11-week study period. The results obtained were that the application of temulawak extract had a significant effect on alanine transaminase (ALT) levels but did not differ between groups. Aspartate transaminase (AST) levels differed at a 35 mg/kg BW dose. Temulawak extract at a dose of 140 mg/kg BW, the De Ritis ratio at normal values. The results of the histopathological analysis showed hepatocyte repair and sinusoidal dilatation were less than optimal at a dose of 140 mg/kg BW. This study concluded that the temulawak extract showed a significant but insignificant difference in the ALT value. The AST value significantly differed in administering temulawak extract at a dose of 35 mg/kg BW. The dose of 140 mg/kg BW controls the value of the De Ritis ratio to the normal value. Temulawak extract is expected to improve the healing of the liver damaged by carcinogenic substances.
Mechanical Performance of Light Weight 3D Printed Interlocked Assemblies
Authors: Yasir Hannan Syed , Pervaiz Salman
Published: February 2023

Topologically interlocked assemblies have traditionally been explored to study properties such as strength, toughness and fatigue when applied axial compressive load. The interlocked assemblies are used in real-life applications ranging from the aerospace industry to the construction sector. This concept is generally applied to segmented blocks to study what parameters affect failure and how the failure occurs. The Segmented interlocked assemblies are investigated to optimize performance and weight compared to a monolithic design with poor strength characteristics. Strength to weight ratio is beneficial to applications where the efficiency of the product relies heavily on the weight. This study is performed on the 3D printed cubes with interlocking geometric slots, and the segmented cubes were investigated for failure through a three-point bending test under different conditions. The study used parameters such as speed of testing, lubrication between blocks, and the shape of the slots. This paper makes use of the Taguchi design of experiments in combination with grey relational analysis to optimize the parameters. Different lubrications were used to create a variation in friction between the blocks simply. After processing the data, it was concluded that the best condition was a circle shape, with lubrication #1 at an indenter speed of 10mm/min, followed by a circle and dry at 5mm/min. Triangle shape with lubrication #1 at a speed of 5mm/min was third in terms of the overall rank. According to the results, the worst-performing condition was a circle shape with lubrication #2 at a 1mm/min speed.
Analysis of Project Monitoring Practices on Implementation of Road Construction in Rwanda. A Case of Sonatube -Bugesera Road
Authors: Theogene MUPENDE
Published: February 2023

The general objective of the study was to analyze the effect of project monitoring practices on implementation of road construction projects in Rwanda. The study was carried out in Kigali, Rwanda, Kicukiro-Bugesera Road. This study was guided by the following specific objectives; determine the effect of communication, determine the effect of monitoring tools, investigate the influence of stakeholder’s participation, establish the effect of staff competency on implementation of road construction projects in Kigali. The research study adopted a descriptive research design targeting 84 project managers, committee members and monitoring committee. A closed ended structured questionnaire will be used to collect primary data from 84 sampled respondents. A pilot study was conducted to ascertain the reliability and validity of the instruments. The quality and consistency of the study was further assessed using Cronbach’s alpha. Data analysis was performed using Statistical Package for Social Science (SPSS) version 23. Data presentation was done using frequency counts, percentages, means, standard deviations, regression, correlation and the information were presented in form of tables. The findings revealed that 52.4% of the respondents strongly agreed that project monitoring tools affects implementation of road construction projects in Rwanda. 41.7% of the respondents agreed, with 0% of the respondent remaining neutral. 5.9 % disagreed and none strongly disagreed. This indicates that the majority of the respondent at 52.4% considers that project monitoring tools affects Project implementation of road construction projects in Rwanda. The study findings revealed that for monitoring processes to function properly it requires management support as a mediating factor for a project to succeed. The study recommends management should give their support to all levels of stakeholders for projects to succeed.

Key Words: Communication, Monitoring Tools, Stakeholder’s Participation, Staff Competency.
Is There a Glass Ceiling in Nepalese Commercial Banks?
Authors: Shrestha Indira
Published: February 2023

This paper aims to ascertain whether there are glass ceilings in Nepalese commercial banks. All of the female branch managers employed by Nepalese commercial banks made up the study's population. 144 women branch managers from commercial banks were taken as the sample size. The sample was drawn from the population using simple random sampling. Information from respondents was gathered through the use of a standardized questionnaire. The survey's questions were based on questions that were derived from (Bergman & Hallberg, 2000). With the aid of statistical techniques like percentage and frequency, a descriptive research approach was used. The glass ceiling variables that could impact women's career growth were corporate culture, corporate climate, and corporate practice. The findings showed that women generally had favorable perceptions of the glass ceiling factors (corporate culture, corporate climate, and corporate practices) that contribute to the presence of the glass ceiling. limitation of the study is that only female branch managers were included in the sample. The implications and scope for the future researcher are also covered.
The prognostic implications of a fragmented QRS pattern in patients diagnosed with heart failure
Authors: DEMİRKIRAN Ahmet , YİLMAZ Mustafa , ŞİT Ömer , ATICI Adem , BARMAN Hasan
Published: February 2023

Objectives: The purpose of this study was to investigate the potential association between the presence of a fragmented QRS (fQRS) pattern on electrocardiogram (ECG) and prognostic outcomes in patients with heart failure (HF).
Methods: In the study, 238 patients with a left ventricular ejection fraction of less than 35% were included. The presence of fQRS pattern on ECG was analyzed in all patients. Patients were divided into two groups based on the presence or absence of fQRS on ECG. The primary clinical end points were all-cause mortality and rehospitalization.
Results: Baseline demographic characteristics were comparable between the groups. Patients with fQRS had a higher frequency of coronary artery disease and atrial fibrillation (72 (76%) vs 90 (62%), (p = 0.023; 27 (29%) vs 25 (17%), (p = 0.038, respectively). Additionally, patients with fQRS had a higher rate of mortality and rehospitalization during the 5-year follow-up period compared to patients without fQRS. (30 (32%) / 28 (19%), (p = 0.028; 56 (60%) / 50 (35%), p < 0.001, respectively). Multivariable logistic regression analysis revealed that the presence of fQRS was independently associated with mortality and rehospitalization ((p = 0.02 and p < 0.001, respectively).
Conclusions: The results of this study suggest that the presence of fQRS on ECG in patients with HF is independently related to a higher risk of mortality and hospitalization. Therefore, the presence of fQRS may be a useful indicator of poor prognosis in these patients.
Evaluation of the Correlation Between Vitamin D Level and Insulin Resistance in Children with Overweight and Obesity
Authors: TUNÇER Esra , KESER Alev , ÜNSAL Emine Nüket , ODABAŞI GÜNEŞ Sevinç , AKIN Onur
Published: February 2023

Aim: This study aimed to evaluate the relationship between vitamin D levels and insulin resistance parameters in children with overweight and obesity. Material and Methods: A total of 174 children, 64.4% (n=112) female, and 35.6% (n=62) male, aged between 6-17 years were included in the study. The participants were divided into three groups as normal (29.9%, n=52), overweight (23.6%, n=41), and obesity (46.5%, n=81) based on the criteria of the World Health Organization body mass index (BMI) classification. The insulin resistance status of the participants was evaluated by homeostatic model assessment of insulin resistance (HOMA-IR), fasting glucose to insulin ratio (FGIR), and quantitative insulin sensitivity check index (QUICKI). Results: HOMA-IR was found higher in the obesity group (3.2±2.1) compared to the overweight (2.2±1.0) and the normal weight (1.5±1.0) groups (p<0.001). It was observed that QUICKI values of the overweight (0.34±0.03) and the obesity (0.33±0.03) groups were lower than the normal weight (0.37±0.03) group (p<0.001). FGIR was noticed as higher in the normal weight (16.8±10.4) group compared to the overweight (10.6±6.0) and the obesity (8.5±5.5) groups (p<0.001). The mean serum 25-hydroxyvitamin D [25(OH)D] levels of the children and adolescents were 19.6±10.7 ng/mL, and no statistically significant difference was found between the groups (p=0.153). A significant weak negative correlation between serum 25(OH)D and HOMA-IR values was found (r=-0.170, p=0.025). Additionally, a weak positive statistically significant correlation was found between serum 25(OH)D level and QUICKI and FGIR values (r=0.173, p=0.022, and r=0.173, p=0.023, respectively). Conclusion: Vitamin D levels can affect insulin resistance parameters.
Czy zasada in dubio pro tributario znajduje zastosowanie w podatku od towarów i usług?
Authors: Rogowska-Rajda Beata
Published: February 2023

Celem artykułu jest udzielenie odpowiedzi na zadane w jego tytule pytanie: „Czy w sytuacji wystąpienia wątpliwości w zakresie treści przepisów o podatku od towarów i usług możliwe jest zastosowanie zasady in dubio pro tributario?” Zasada ta daje bowiem pierwszeństwo wykładni językowej, a wykładnię unijną respektuje jedynie wtedy, kiedy jej zastosowanie prowadzi do wykładni korzystniejszej dla podatnika. Pozostaje to jednak w sprzeczności z obowiązkiem stosowania wykładni zgodnej w odniesieniu do zharmonizowanych przepisów o VAT. Zastosowana metoda badawcza polega na analizie przede wszystkim orzeczenia Trybunału Sprawiedliwości w sprawie Herst, jak również wydanej w tej sprawie opinii Rzecznik Generalnej, uzupełnionej analizą innych – wybranych jako reprezentatywne w sprawie – wyroków Trybunału w zakresie wykładni prounijnej. Badanie wzbogacono również o poglądy doktryny krajowej i zagranicznej w badanych obszarach. Jak wykazano – na zadane w tytule pytanie należy odpowiedzieć twierdząco, aczkolwiek odpowiedź ta wymaga doprecyzowania, że zasada ta, postrzegana w sposób obiektywny, możliwa jest do zastosowania wyłącznie wtedy, jeśli nie jest możliwe zastosowanie wykładni unijnej, przy czym ten brak możliwości zastosowania musi mieć również charakter obiektywny. Zaprezentowany pogląd zostanie jednak zweryfikowany w toku stosowania prawa przez sądy administracyjne, gdyż to właśnie judykatura wyznaczy granice obowiązywania zasady in dubio pro tributario w podatku od towarów i usług.
Membrane Separations
Authors:   Atal Bihari Vajpayee Vishwavidyalaya Bilaspur, Chhattisgarh, Saha S.N.
Published: February 2023

Membrane technology is widely utilised in industries for separation, concentration, filtering, and extraction operations. Membrane technology carries out various applications by utilising simple and specially designed semi-permeable membranes. It uses little energy and is thus considered a green technology. Ultrafiltration (UF), Microfiltration (MF), Nano-filtration (NF), and Reverse osmosis (RO) are membrane filtration methods that have a major influence on the organoleptic and nutritional qualities of juice. The adoption of a membrane method linked with enzymatic hydrolysis resulted in clarified and concentrated fruit juices with good sensory and nutritional quality. Membrane fouling is a significant problem of membrane-based separation processes. Membrane procedures powered by pressure, such as MF, UF, NF, and RO, allow for the separation of components with a wide variety of particle sizes. Because of this, they have a wide range of uses in the food processing business.
Environmental Ethics and Mental Health during COVID-19
Authors: DÜZENCİ Serhat , MALAK Bahanur
Published: February 2023

As the cause of the COVID-19 pandemic, climate change, population density, ecological changes, etc. natural phenomena are shown. The physical, chemical, biological, socioeconomic, cultural and psychological effects of COVID-19 have been felt all over the world. COVID-19 negatively affects the environment with an unbalanced increase in medical waste and disposable products, while quarantine and pandemic measures have given an opportunity for nature to renew itself. The causes and consequences of COVID-19 have brought the concepts of environmental health and therefore environmental ethics to the agenda of healthcare professionals. As the environmental ethics attitudes and behaviors of health professionals develop, health professionals will be able to take initiatives to create these attitudes and behaviors in society. Environmental ethics has been evaluated in the context of public health, mostly in the physical health. However, environmental ethics is also very important in terms of community mental health. Living in an unhealthy environment threatens mental health. Because people want to live in a safe environment, every factor that threatens this trust poses a risk for mental health. There is actually literally no way to talk about happiness in an environment where there is no environmental order and nature is deteriorated and polluted. Therefore, we aimed to explain the concepts of environmental health, environmental ethics and mental health during the COVID-19 process. Thus, an important strategy development in the pandemic process can be achieved by enabling the assessment and management of the causes of the COVID-19 pandemic from a broader perspective.
Investigation of the Causes of Negative Attitudes towards Women Incompatible with Gender Stereotypes within the Context of Social Identity Theory
Authors: KAŞDARMA Ezgi
Published: February 2023

The primary gender stereotypes accepted in mainstream social psychology describe women as low in competence and high in warmth, men as having low warmth and high competence. Women who are incompatible with stereotypes are exposed to negative attitudes. Exposure to negative attitudes damages the psychological well-being of these group members. Stereotypes and negative attitudes towards members of social groups contribute to the persistence of their low status. Explaining the causes of gender stereotypes and negative attitudes towards women incompatible with stereotypes is an overlooked topic in mainstream social psychology. In order to change the ongoing gender system, where women have a disadvantageous status compared to men, it is necessary to understand the reasons for negative attitudes towards women who are incompatible with stereotypes. Based on the suggestions and findings of Social Identity Theory, explanations about negative attitudes towards women who are incompatible with gender stereotypes are presented in this study. It is concluded that most men reveal negative attitudes towards these women because women with high competency threaten men who can affirm their social identity through competency. Most men define their social identity through status-related traits such as competency. Due to the threat to men's social identity by women with high competence, it is concluded that negative attitudes towards these women are revealed by most of the men, based on theoretical suggestions. It is necessary to understand the identity management strategies to explain women's negative attitudes towards their fellows who are incompatible with stereotypes. According to the theoretical suggestions and related studies, it is concluded that the adoption of individual mobility and social creativity strategies reveal negative attitudes toward fellows who are incompatible with stereotypes. Although it is expected that women who adopt the social competition strategy have positive attitudes towards their fellows who are inconsistent with gender stereotypes, the level of adoption of this strategy is low. When theoretical suggestions and study findings are brought together, it is possible to understand the reasons for the negative attitudes towards women who are incompatible with gender stereotypes.
Interventions for Forgiveness: A Review
Authors: SAYAN KARAHAN Ayşegül
Published: February 2023

This review was conducted to draw attention to the issue by addressing the effectiveness of interventions for forgiveness. In order to identify studies dealing with interventions for forgiveness, published in Turkish or English and after 2010 in ScienceDirect, Pubmed, Turkish Psychiatry Index and TR Index databases, the keywords "forgiveness", "intervention", "effectiveness" were entered and scanned between January and March 2022. The bibliographies of the articles on forgiveness were scanned, review and descriptive studies were excluded. As a result, 24 studies were included in the review. When the studies are examined, it is seen that the applied interventions make a significant difference, and long-term follow-up is important. There seems to be a need for studies testing interventions for forgiveness in our country.
Experiences of Nursing Students in Practicing Blood Transfusion
Authors: ÖZEL Filiz , BULANTEKİN DÜZALAN Özlem
Published: February 2023

Healthcare professionals need to know about blood transfusion. The purpose of this study is to determine the experiences of nursing students on blood transfusion and their opinions on the influencing factors. In this qualitative study, the sample of the study consisted of 12 second, third, and fourth-year nursing students who were continuing their education at a state university. In the study, data were collected by conducting in-depth interviews via a semi-structured interview form. In the study, the data were coded under two themes including nursing students’ experiences with blood transfusion (three sub-themes: level of theoretical knowledge about transfusion, fear of making mistakes, and inadequate practice) and the factors affecting these experiences (four sub-themes: factors related to patients’ relatives, factors related to patients, factors related to the practice and training related factors). As a result of the study, nursing students were observed to have different fears regarding blood transfusion. In the education of nurses, it is recommended to organize training on this subject for nursing educators and manager nurses.
Russian society and state in the context of global multipolarity. Socio-political situation of Russia in 2022 : [monograph]
Authors:   Institute of Socio-Political Research of FCTAS RAS, Moscow, Russian Federation, Levashov Victor K.
Published: February 2023

В монографии изложены результаты научных исследований, выполнен- ных сотрудниками ИСПИ ФНИСЦ РАН в рамках тематики государственных заданий Министерства науки и высшего образования Российской Федерации. Главным событием 2022 года, определившим социально- политическую ситуа- цию в стране, стала специальная военная операция РФ на Украине и вызван- ные ею санкции недружественных стран Запада. В монографии отражены результаты исследований социально-политической и социально-демографи- ческой ситуации в стране, проведенных сотрудниками института и касаю- щихся актуальных проблем жизнедеятельности российского гражданского общества и социального государства. Монография адресована исследователям, аналитикам, преподавателям, аспирантам, студентам, специализирующимся на изучении социально-по- литических процессов, и социально-демографических процессов, полити- кам, организаторам и активистам избирательных кампаний, управленче- скому персоналу. В монографии изложены результаты научных исследований, выполненных сотрудниками ИСПИ ФНИСЦ РАН в рамках тематики государственных заданий Министерства науки и высшего образования Российской Федерации. Главным событием 2022 года, определившим социально-политическую ситуацию в стране, стала специальная военная операция РФ на Украине и вызванные ею санкции недружественных стран Запада. В монографии отражены результаты исследований социально-политической и социально-демографической ситуации в стране, проведенных сотрудниками института и касающихся актуальных проблем жизнедеятельности российского гражданского общества и социального государства. Монография адресована исследователям, аналитикам, преподавателям, аспирантам, студентам, специализирующимся на изучении социально-политических процессов, и социально-демографических процессов, политикам, организаторам и активистам избирательных кампаний, управленческому персоналу.
Fiche botaniques forestières, industrielles et commerciales : Iroko
Authors: Aubréville André
Published: February 2023

Aucun résumé disponible.
Az import végső felhasználási célokhoz rendelése a 2020. évi magyar ÁKM elemzése alapján
Authors: Forgon Mária , Varga Éva
Published: February 2023

A forrás- és felhasználástáblák, valamint az ezekre épülő nagy ÁKM-táblák lehetőséget adnak az import felhasználásának különböző szempontok szerinti elemzésére, a közvetlen és a halmozott, továbbá a teljes importigényesség vizsgálatára. Tanulmányunk középpontjában a 2020. évi nagy ÁKM-táblákból kinyerhető importfelhasználási adatok elemzése áll, esetenként azok összevetése a 2015., illetve a 2018. évi ÁKM-ből számolt mutatókkal. Az elemzés alapját képező mutatók az ÁKM-táblák és a Leontief-inverz alapján készültek, segítségükkel végső felhasználási célokhoz rendelhető a teljes import.
Influence of non-irrigation and seasonality on wine colour, phenolic composition and sensory quality of a grapevine (Vitis vinifera cv. Callet) in a Mediterranean climate
Authors: Pou Alicia , Balda Pedro , Cifre Josep , Ochogavia Joan Manuel , Ayestaran Belén , Guadalupe Zenaida , Llompart Miquel , Bota Josefina , Martínez Leticia
Published: February 2023

Most vineyards in Mediterranean areas are cultivated using a training system and drip irrigation. However, the increasing risk of water deficit stress due to global warming will mean that viticulture need to adapt to a tougher water-saving policy. Thus, we investigated the effects of total suppression of irrigation on a grapevine (Vitis vinifera cv. Callet) and the phenolic composition and sensory quality of this native red variety wine from the Balearic Islands over three seasons. Significant yield reductions of up to 15.6 %, 17.2 % and 22.2 % were observed in non-irrigated (NI) plants in 2016, 2017 and 2018 respectively, compared to irrigated plants (I); however, wine quality parameters improved. In the years with the highest rainfall (715 mm in 2016 and 799 mm in 2017), NI favoured the enrichment of sugars, anthocyanins and phenolic compounds in the wine and enhanced the development of aromatic components. However, with lower rainfall (524 mm in 2018), the NI treatment appeared to diminish the quality of the wine, particularly affecting the global sensory quality of the wines. Thus, development of specific water strategies tailored to the vineyard, year, vintage and grape variety may regulate the phenolic composition of red wines to meet production goals and reduce total water consumption.
POLÍTICAS PÚBLICAS E NORMAS JURÍDICAS APLICÁVEIS AO DIREITO À ALIMENTAÇÃO AGROECOLÓGICA NA CIDADE DE DOURADOS/MS
Authors: Bezerra Guimarães Verônica Maria , Caramit Baltha Franciele Roberto
Published: February 2023

O direito à alimentação adequada é um direito humano básico cuja realização é imprescindível para o direito à vida. Teve origem na Declaração Universal dos Direitos Humanos, sendo dever do Estado garantir as condições para sua efetivação através de políticas públicas que garantam o acesso a uma alimentação suficiente e saudável levando em consideração a proteção ambiental. Em 2003, o Governo Federal passou a assumir os compromissos mais efetivos com a segurança alimentar e nutricional, através da construção da agenda da Segurança Alimentar e Nutricional. O objetivo deste trabalho foi identificar a cartografia das políticas públicas aplicáveis ao direito à alimentação agroecológica no município de Dourados/MS, compreendendo as atividades da Política Nacional de Segurança Alimentar. A metodologia utilizada foi a pesquisa bibliográfica; a análise de dados quantitativos e qualitativos e a realização de entrevistas abertas e semiestruturadas. As entrevistas foram realizadas em Mato Grosso do Sul com: a presidente do Conselho Municipal e de Segurança Alimentar e Nutricional de Dourados/MS; a ex-secretária do COMSEA-Dourados; a secretária executiva da Câmara Intersetorial de Segurança Alimentar e Nutricional; uma pesquisadora em Saúde Pública da Fundação Oswaldo Cruz e um produtor agroecológico da Associação de Produtores Orgânicos.
SINTOMAS DEPRESSIVOS E ANSIOSOS EM UNIVERSITÁRIOS: UM ESTUDO NUMA UNIVERSIDADE DO SUL DO TOCANTINS
Authors: Da Silva Jeann Bruno Ferreira , LOPES MARINHO VINÍCIUS , Guarina da Silva Tallita Laren , Brito Salera Ítalo , Ribeiro Dias Aline
Published: February 2023

Este estudo objetivou Investigar a existência de sintomas de depressão e ansiedade em estudantes dos cursos de uma Universidade Pública do Sul do Tocantins. A metodologia empregada foi pesquisa aplicada, transversal quantitativa e descritiva, com entrevistas à 480 estudantes de uma universidade pública da região sul do Estado do Tocantins. Como instrumentos foram utilizados Inventários de Ansiedade e Depressão de Beck e um Questionário Sociodemográfico através de formulário eletrônico. Os resultados apontam que, dos 480 (quatrocentos e oitenta) discentes que participaram da pesquisa, os dados apontaram que 23% apresentavam nível mínimo de ansiedade, 36% nível leve, 17% nível moderado e 24% nível grave. Já sobre a sintomatologia depressiva, 6% dos entrevistados apresentaram nível de depressão considerado moderado a grave, 14% grave, 38% mínimo e 42% leve a moderado. Conclui-se que a população universitária estudada experimenta sintomas ansiosos e depressivos clinicamente significativos, podendo experimentar de transtornos mentais que, se não intervistos, podem se agravar.

Palavras-chave: Depressão; Ansiedade; Estudantes Universitários; COVID-19.