bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of digital health on the quality of primary care for people with chronic noncommunicable diseases: A scoping review protocol
Authors: Xavier Pedro Bezerra , Silva Ísis de Siqueira , de Figueiredo Renan Cabral , de Araújo Aguinaldo José , da Silva Amanda Jéssica Bernardo , Uchôa Severina Alice da Costa
Published: February 2025

Background

Chronic Non-Communicable Diseases (NCDs) represent a significant global challenge, especially in low- and middle-income countries. The introduction of digital health in Primary Health Care (PHC) has the potential to improve the quality of care for people with NCDs by offering tools such as telemedicine, mobile applications and other information and communication technologies. The aim of this study is to identify and map global experiences of using Information and Communication Technologies (ICTs) in primary care for non-communicable diseases and assess their impact on the quality of care in PHC.

Methods

This study presents a scoping review protocol based on the Joanna Briggs Institute criteria and the PRISMA-ScR guidelines. The review will be carried out in nine stages, including defining the aim and research questions, developing inclusion and exclusion criteria, and searching, selecting, extracting and analyzing the evidence. The databases consulted include MEDLINE/PubMed, JBI Evidence Synthesis and Open Science Framework.

Results

The review will identify and map global experiences in the use of ICTs in primary care for NCDs and assess their impact on the quality of care in PHC. It is hoped to find studies that address the use of digital technologies for early detection, management and follow-up of NCDs, as well as their integration with traditional health systems.

Conclusions

The integration of digital technologies into PHC has the potential to improve the quality of care, but it can also accentuate inequities. It is necessary to consider digital health literacy, access to tools, and legal and ethical aspects of data protection. The review will highlight the need for robust policies and adequate infrastructure to support the effective implementation of digital health in PHC.
Effects of speed, agility, and quickness (SAQ) training on soccer player performance—a systematic review and meta-analysis
Authors: Sun Min , Soh Kim Geok , Ma Shuzhen , Wang Xinzhi , Zhang Junlong , Yaacob Azhar Bin
Published: February 2025

Background

Previous studies have reported on the impact of Speed, Agility, and Quickness (SAQ) training on the performance of soccer players. However, there is still controversy regarding the results. This systematic review and meta-analysis aim to accurately assess the effects of SAQ training on the performance of soccer players.

Methods

We conducted a comprehensive search on March 15, 2024, using Web of Science, PubMed, Scopus, and EBSCOhost. Eligibility criteria for selecting studies were established based on the PICOS framework: (i) Population—healthy soccer players; (ii) Intervention—SAQ training; (iii) Comparison condition (conventional training or traditional training); (iv) Outcome—physical performance (speed, agility, strength, etc.); (v) Study design—randomized controlled trials. The PEDro scale was employed to evaluate the methodological quality of each study, and a random-effects model was used for the meta-analysis.

Results

A total of 11 studies met the inclusion criteria for the systematic literature review. One study with low PEDro score was excluded, and one was excluded based on Cochrane bias risk assessment. Finally, 9 studies were included in the meta-analysis, comprising 498 soccer players. Overall, the results indicated a significant impact of SAQ training on physical qualities and dribbling speed among soccer players. Specifically, there was a moderate effect size for sprint performance (5m, 10m, 20m) (ES = 0.75; p < 0.01), change of direction ability (COD) (ES = 0.35; p < 0.001), power (vertical and horizontal jumps) (ES = 0.67; p < 0.01), while flexibility showed no significant impact (ES = 0.11; p > 0.05). Moreover, change-of-direction dribbling demonstrated a significant effect (ES = 0.58; p < 0.01).

Conclusion

Overall, SAQ training effectively enhances speed, COD, explosiveness, and change-of-direction dribbling specific performance in adolescent soccer players, particularly in sprinting. However, it does not have an advantage in improving flexibility. Further high-quality studies encompassing a broader range of exercises are needed to fully determine the effectiveness of SAQ training in improving other physical qualities and technical skills of soccer players, as well as ultimately enhancing match performance.
Spatial relationship between carbon emissions and ecosystem service value based on land use: A case study of the Yellow River Basin
Authors: Muga Gubu , Tiando Damien S. , Liu Chong
Published: February 2025

Land use changes significantly impact both carbon emissions and ecosystem service value (ESV). However, few studies have been conducted on the spatial relationship between land use carbon emissions (LUCE) and ESV. Thus, focused on the Yellow River Basin (YRB), this study independently calculates carbon emissions from land use change (LUCE) and ecosystem service values (ESV) in the region. Utilizing spatial autocorrelation methods, we analyze the spatiotemporal pattern of LUCE and ESV and subsequently apply the bivariate spatial autocorrelation method to explore their spatial relationship. The results prove that: (1) The YRB’s LUCE has continuously increased, with construction land acting as the dominant carbon source and woodland acting as the main carbon sink. The LUCE in the YRB had a positive spatial autocorrelation. (2) The YRB’s ESV increased. Spatially, the ESV in the YRB showed a positive autocorrelation. (3) Both LUCE and ESV exhibited negative spatial autocorrelation, with predominant patterns of bivariate localized spatial autocorrelation identified as High-Low agglomeration (H-L) and Low-High agglomeration (L-H). Cities with the L-H pattern were primarily located in Qinghai Province and Inner Mongolia. In contrast, cities with the H-L pattern were mainly observed in the western section of Shandong and the northeastern region of Henan. The study revealed the negative impact of increased carbon emissions from land use on the value of ecosystem services, providing assistance in the development of relevant environmental policies and promoting sustainable development in the YRB.
Risks of mortality for various phenotypes in patients with type 2 diabetes mellitus in the Novosibirsk region
Authors: Bondar I. A. , Shabelnikova O. Y.
Published: February 2025

BACKGROUND: Type 2 diabetes mellitus (T2DM) is a disease with high prevalence and early mortality, and identifying groups at risk for adverse outcomes is important in secondary prevention.

AIM: To study clinical, metabolic and genetic risk factors for deaths in various clinical phenotypes in patients with type 2 diabetes mellitus in the Novosibirsk region.

MATERIALS AND METHODS: A prospective cohort study was conducted of 2507 patients with T2DM. The follow-up duration was 6.3±2.5 years. Depending on the level of C-peptide and the HOMA-IR index, patients were divided into 3 phenotypes: insulinopenic (n=288), classic (n=1921), insulin-resistant (n=298). Fatal outcome for the period from 2014 to 31.12.2022 was recorded in 592 patients (23.6%). DNA isolation and genotyping of structural variants of the TCF7L2(rs7903146), ATM(rs11212617) genes were performed by PCR.

RESULTS: The main cause of death in patients with T2DM in all phenotypes was CVD (63.8%). Patients with an insulin-resistant phenotype had a significantly shorter duration of diabetes at the time of death, 12.3±5.5 years, compared with the classic and insulinopenic phenotype (p<0.001). Risk factors for mortality from all causes according to multivariate Cox regression analysis (OR) were the duration of T2DM (1.043, p<0.001), the level of HbA1c (1.131, p<0.001), creatinine (1.013, p=0.002), the T allele of the TCF7L2(rs7903146) gene (OR=1.431, p=0.017) and allele C of the ATM(rs11212517) gene (OR=1.509, p=0.007). Predictors of cardiovascular death were HbA1c (OR=1.129, p=0.001), duration of diabetes (OR=1.041, p=0.002), creatinine level (OR=1.015, p=0.004), the T allele of the TCF7L2(rs7903146) gene (OR=1.719, p=0.005) and allele C of the ATM gene (OR=1.539, p=0.024).

CONCLUSION: The study found that patients with an insulin-resistant had a poor prognosis. The main predictor of general and cardiovascular death was HbA1c. The T allele of the TCF7L2(rs7903146) gene increased the risk of overall mortality by 43.1%, the C allele of the ATM(rs11212617) gene by 50.9%.
Words of gratitude to our reviewers: your effort is visible in every article
Authors: Editorial Article
Published: February 2025

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Captura do discurso
Authors: Gallas Ana Kelma Cunha , Perez Olívia Cristina
Published: February 2025

Este estudo analisa as estratégias discursivas do Observatório Interamericano de Biopolítica (OIB) em suas campanhas antigênero no Brasil, investigando como essas estratégias se conectam ao fenômeno de captura do discurso, conforme descrito por Lewin (2021). A pesquisa, de natureza qualitativa, realiza-se pelo batimento entre teoria e análise, examinando, nos discursos do OIB, a aplicação de quatro táticas de captura discursiva: ressignificação, deslocamento, mimetismo/apropriação, distorção/reutilização. O estudo revela como o OIB manipula conceitos progressistas, ressignificando-os para sustentar uma retórica conservadora, contribuindo para o entendimento das dinâmicas de manipulação discursiva e mobilização política empregadas por grupos antigênero no Brasil.
Advancing AI: A Comprehensive Study of Novel Machine Learning Architectures
Authors: Boya Marqas Ridwan , Saman M. Almufty  , Renas R. Asaad  , Tamara Saad mohamed Dr.
Published: February 2025

The rapid evolution of machine learning (ML) and artificial intelligence (AI) has led to groundbreaking advancements in computational models, empowering applications across diverse domains. This paper provides an in-depth exploration of advanced ML architectures, including transformers, Graph Neural Networks (GNNs), capsule networks, spiking neural networks (SNNs), and hybrid models. These architectures address the limitations of traditional models like convolutional and recurrent neural networks, offering superior accuracy, scalability, and efficiency for complex data. Key applications are discussed, ranging from healthcare diagnostics and drug discovery to financial fraud detection, autonomous systems, and logistics optimization. Despite their potential, these architectures face challenges such as computational overhead, scalability, and interpretability, necessitating interdisciplinary solutions. The paper also outlines future directions in edge computing, explainable AI, quantum machine learning, and few-shot learning, emphasizing the transformative role of advanced ML architectures in reshaping AI’s future.
Arabinogalactan in the metabolism technology of probiotic culture in a plant-based drink medium.
Authors:   South Ural State University, Popova Natalia , Kameneva Ksenia ,   South Ural State University
Published: February 2025

Plant-based oat milk drinks, serving as a source of beneficial fiber, essential amino acids, fats, and carbohydrates, as well as vitamins and minerals, represent an alternative to tradi-tional dairy products. However, plant-based drinks may contain bioactive components that hinder the absorption of nutrients, and enhancing the nutritional value of plant-based drinks, improving their sensory characteristics, possibly through fermentation, is feasible. Increasing fermentation activity is possible by introducing prebiotics, particularly arabinogalactan, which is the focus of our research. As a basis for the plant probiotic drink, oat milk was chosen, and a complex probiotic culture starter was used: Streptococcus thermophilus, Lactobacillus bulgaricus, Lactobacillus casei, with arabinogalactan added at a concentration of 0.5 to 3 % by weight of the drink. Preliminary studies have shown that the most favorable addition of arabinogalactan occurs during the fermentation stage along with the starter culture. The efficiency of the fermentation process was assessed by changes in titratable acidity, accumulation of lactic acid, exopolysaccharides, and the antioxidant activity of the produced probiotic drinks. The conducted research has demonstrated the ability of the complex probiotic culture starter, including Streptococcus thermophilus, Lactobacillus bulgaricus, Lactobacillus casei, to thrive in the plant-based oat drink environment. Under optimal conditions for the development of these microbial strains, a fermented product with high sensory properties is produced. The introduction of the arabinogalactan polysaccharide during the fermentation stage of the plant-based medium activates the fermentation process, resulting in an intensification of changes in titratable acidity and accumulation of lactic acid – on average by 9–22.7 %, an increase in the amount of exopolysaccharides by 15.8–54 %. Improvement in the functional properties of probiotic plant-based drinks has also been observed, particularly in enhancing their antioxidant activity by 37.7–93.4 %. These changes are reflected in the consistency and uniformity of the drink structure, as well as its aromatic and flavor profile.
COORDINATING AND OPTIMIZING TWO-WAREHOUSE INVENTORY SYSTEMS: A MATHEMATICAL PROGRAMMING APPROACH
Authors: Sutrisno Sutrisno , Widowati Widowati , Azis Moh. Ivan , Aldila Dipo
Published: February 2025

Effective supplier and carrier selection plays a pivotal role in supply chain management, ensuring maximum profitability. This study introduces an innovative decision-support system designed for supplier and carrier selection problems in static two-warehouse inventory systems. The model assumes warehouse collaboration, where warehouses consolidate efforts to fulfill overall demand. To address this, a mathematical programming approach is developed and solved using the LINGO 21.0 optimization software. Experimental results reveal that the proposed model delivers optimal decisions. Even though challenges are still available on the constraint functions and the derivation of parameters' values, the results provide positive managerial insights that offer valuable tools for stakeholders to improve supply chain efficiency.
L‐arginine ameliorates hypertension and cardiac mitochondrial abnormalities but not cardiac injury in male metabolic syndrome rats
Authors: Tagami Kaito , Okuzawa Touko , Yoshida Keisuke , Mishima Rin , Obara Natsuki , Kunimatsu Asuko , Koide Mayako , Teranishi Tamami , Itakura Koji , Ikeda Katsuhide , Murohara Toyoaki , Nagata Kohzo
Published: February 2025

L‐Arginine supplementation has beneficial effects on metabolic disorders in rodents. We here investigated the effects of exogenous L‐arginine on cardiac pathology and mitochondrial reactive oxygen species (ROS) production and dynamics in DahlS.Z‐Leprfa/Leprfa (DS/obese) rats, a model of metabolic syndrome (MetS). DS/obese rats and their lean homozygous littermate (DahlS.Z‐Lepr+/Lepr+, or DS/lean) controls were provided with drinking water containing 0.50% L‐arginine‐HCl or 0.85% L‐alanine (isonitrogenous control) from 13 to 17 weeks of age. L‐Arginine supplementation markedly alleviated hypertension without affecting cardiac injury in MetS rats. It also attenuated the increase in ROS production apparent in cardiac mitochondria isolated from MetS rats as well as suppressed the associated upregulation of Nox4 mRNA and protein in the heart. Furthermore, L‐arginine reversed the decrease in the size of cardiac mitochondria as well as changes in the expression of DRP1 and OPA1 proteins apparent in the L‐alanine–treated MetS rat heart. Cardiac arginase II gene expression and arginase activity were increased by L‐arginine treatment in MetS rats but not CONT rats. L‐Arginine supplementation thus ameliorated hypertension and cardiac mitochondrial abnormalities in MetS rats, with the lack of a cardioprotective effect possibly being due to increased arginase activity.
Local grammar and speech act analysis: a case study of compliments
Authors: Tang Mengyuan
Published: February 2025

As local grammar starts to receive attention in the field of corpus linguistics, this study examines the local grammar of the speech act of complimenting. Utilizing the corpus from the first three seasons of Modern Family, the research identifies ten functional categories, revealing both commonalities and individualities in their use based on explicit and implicit strategies. A total of 31 explicit compliment patterns and 2 implicit ones are classified. The application of local grammar offers a clear and holistic perspective, enriching corpus pragmatics and providing communicative instructions for EFL and ESL learners.
Continuity property of pseudodifferential operators from the weak Hardy spaces to the weak Lebesgue space
Authors: Deng Yu-Long
Published: February 2025

This paper discusses the boundedness of pseudodifferential operator on weak Hardy space and provides a sufficient condition such that the operator is continuous from the weak Hardy space into the weak Lebesgue space.
Estimating individual contributions to team success in women’s college volleyball
Authors: Powers Scott , Stancil Luke , Consiglio Naomi
Published: February 2025

The progression of a single point in volleyball starts with a serve and then alternates between teams, each team allowed up to three contacts with the ball. Using charted data from the 2022 NCAA Division I women’s volleyball season (4,147 matches, 600,000+ points, more than 5 million recorded contacts), we model the progression of a point as a Markov chain with the state space defined by the sequence of contacts in the current possession. We estimate the probability of each team winning the point, which changes on each contact. We attribute changes in point probability to the player(s) responsible for each contact, facilitating measurement of performance on the same point scale for different skills. Traditional volleyball statistics do not allow apples-to-apples comparisons across skills, and they do not measure the impact of the performances on team success. For adversarial contact groups (serve/reception and set/attack/block/dig), we estimate a hierarchical linear model for the outcome, with random effects for the players involved; and we adjust performance for strength of schedule not only on the conference/team level but on the individual player level. We can use the results to answer practical questions for volleyball coaches.
Effect of hybridization type, hole-distance and number of holes on the resistance of intraply hybrid composite plates against multiple impact
Authors: Deniz Mehmet Emin , Karakuzu Ramazan
Published: February 2025

In this study, the effects of the hole-distance from impact point and numbers of holes on carbon-glass/epoxy composite plates formed by three different intraply hybridizations subjected to repeated (multiple) impact loading with 8 J energy level are examined experimentally. The samples were subjected to multiple impact loading until perforation, which is determined by the impactor moving completely through the samples. The number of repeats for each sample was determined by the impactor perforating the sample. In order to better interpret the effect of the test parameters after of the impact tests, contact force-time and contact force-deflection, contact force-number of repeats and number of repeats-hybridization type change graphs of the samples are given for each hybridization type. Thus, the effects of both hybridization type and number and distance of holes on the repeated impact resistance of carbon-glass/epoxy intraply hybrid composite plates were investigated. Considering all test parameters, the absence of a hole and the hole’s near to the center of the sample significantly affects the sample stiffness, resulting in lower impact resistance. The presence of the hole and its distance from the impact point made the sample more resistant to impact. While the highest number of repeats was obtained for samples no-hole (d0h0), the lowest number of repeats was obtained for samples with four holes at a distance of 10 mm and 20 mm from the impact point. For all three hybridization types, the contact force value gradually decreased as the number of impact repeats of the samples increased. When the change in the damage areas of the samples was examined, the largest damage area occurred in the samples without holes (d0h0). Damage progression generally occurred in the 0° orientation of the lower layer.
Design and development of welding electrode for structural steel
Authors: Kumar K. , Sharma L. , Chhibber R. , Mohapatra S. K. , Sharma R. K.
Published: February 2025

Due to the large number of consumables available, the flexibility required to achieve appropriate properties in the welded joint is very high. Fundamental knowledge about development of different electrodes for structural steel, of which information is scarce in international welding literature. In present work six rutile coated electrodes were prepared by increasing calcite content, at the expense of cellulose and Si-bearing components like mica and china clay, in the fluxes. This modification produced an increase in the slag basicity, which caused a marked increment in all-weld-metal toughness and modifications in operational behavior with a decrease in penetration and width of the weld bead, while maintaining the typical excellent operational characteristics of rutile electrodes. Microstructure examination of six electrodes indicates the presence of inclusions and secondary phase particles. Maximum tensile strength of 430 N/mm2 while minimum tensile strength of 323 N/mm2 was observed for 7.5 % and 12.5 % calcite content. In F position, 7.5 %, 10 %, 12.5 % calcite was faster than 15 %, 17.5 % and 20 % calcite. For DC (+), 15 %, 17.5 %, 20 % calcite presented higher spatter than 5 %, 10 %, 12.5 % calcite.
Adaptation of Spiritual Intelligence Scale for Turkish: a validity and reliability study
Authors: Tekke Mustafa , Kumru Mustafa
Published: February 2025

Background: This manuscript adapts the concept of spiritual intelligence, examining its growing significance and its potential benefits to Turkish literature.

Objective: It delves into the concept of spiritual intelligence, outlining its components like critical existential thinking, personal meaning production, transcendent awareness, and conscious state expansion.

Method: A total of 382 participants were recruited accordingly. Confirmatory factor analysis (CFA) supported a single-factor model for the Turkish version of Spiritual Intelligence Scale (SIS), indicating good fit with the data. Reliability was assessed using Cronbach’s alpha (.80) and test-retest reliability (.86), demonstrating the scale’s internal consistency and stability. Item-total correlations ranged from .13 to .62, with all items significantly correlating with the total score.

Conclusion: The manuscript adapts the SIS into the Turkish language. These findings suggest the SIS is a valid and reliable tool for measuring spiritual intelligence in Turkish-speaking populations.
The medial olivocochlear efferent pathway potentiates cochlear amplification in response to hearing loss
Authors: Quiñones Patricia M. , Pei Michelle , Srivastava Hemant , Cobo-Cuan Ariadna , Morán Marcela A. , Kim Bong Jik , Walker Clayton B. , Serafino Michael J. , Macias-Escriva Frank , Wang Juemei , Dewey James B. , Applegate Brian E. , McGinley Matthew J. , Oghalai John S.
Published: February 2025

The mammalian cochlea receives efferent feedback from the brain. Many functions for this feedback have been hypothesized, including on short timescales, such as mediating attentional states, and long timescales, such as buffering acoustic trauma. Testing these hypotheses has been impeded by an inability to make direct measurements of efferent effects in awake animals. Here, we assessed the role of the medial olivocochlear (MOC) efferent nerve fibers on cochlear amplification by measuring organ of Corti vibratory responses to sound in both sexes of awake and anesthetized mice. We studied long-term effects by genetically ablating the efferents and/or afferents. Cochlear amplification increased with deafferentation using VGLUT3-/-mice, but only when the efferents were intact, associated with increased activity within OHCs and supporting cells. Removing both the afferents and the efferents using VGLUT3-/-Alpha9-/-mice did not cause this effect. To test for short-term effects, we recorded sound-evoked vibrations while using pupillometry to measure neuromodulatory brain state. We found no state dependence of cochlear amplification or of the auditory brainstem response. However, state dependence was apparent in the downstream inferior colliculus. Thus, MOC efferents upregulate cochlear amplification chronically with hearing loss, but not acutely with brain state fluctuations. This pathway may partially compensate for hearing loss while mediating associated symptoms, such as tinnitus and hyperacusis.

Significance StatementThe functional role of efferent innervation of the mammalian cochlea has remained in question. Here we show that the medial olivocochlear efferent system chronically potentiates cochlear sensitivity in response to removing the afferent signal but does not affect sensitivity in response to fluctuations in pupil-indexed brain state. While partially compensating for hearing loss, the efferent-mediated chronic potentiation may also contribute to associated symptoms of hearing loss, such as tinnitus and hyperacusis.
Human Trafficking Prevention and Combat Under Regulations of International Law and Practice in Vietnam
Authors: Thuong Mac Thi Hoai
Published: February 2025

The situation of human trafficking crime is becoming increasingly complicated, evidenced by an increasing trend in severity, number of cases, and the use of sophisticated methods and tricks. Human trafficking is identified by the United Nations as one of the four most dangerous crimes in the world, as outlined in the Global Crime Prevention Program 2013. It is conducted by organized, transnational criminal groups. Therefore, international cooperation in addressing it is an indispensable and objective requirement. Vietnam has been actively participating in international commitments to combat human trafficking prevention, such as International Convention on the Rights of the Child (1989), the Optional Protocol to the International Convention on the Rights of the Child, Trafficking in Children, Child Prostitution and Child Pornography (2000), United Nations Convention against Transnational Organized Crime (2000), the ASEAN Convention Against Trafficking in Persons, Especially Women and Children (ACTIP Convention), among others. By analyzing both international and Vietnamese laws on human trafficking prevention, combined with the practice of anti-trafficking efforts in Vietnam, this paper highlights that while current Vietnamese law has been promoting its positive effects, some limitations and shortcomings need to be addressed in order to comply with international law and meet practical requirements of anti-trafficking efforts. Thereby, the paper proposes some recommendations for improving Vietnamese law on human trafficking prevention to align with the requirements of international legal standards and the actual needs of human trafficking prevention in Vietnam.
Optimizing the Use of Online Single Submission to Accelerate Business Licensing for Micro Enterprises
Authors: Rahayu Sang Ayu Putu , Puteri Dina Silvia
Published: February 2025

This study explores the optimization of the Online Single Submission (OSS) system, specifically the Risk-Based Approach (RBA), to accelerate business licensing for micro, small, and medium enterprises (MSMEs) in Kebojongan Village, which is home to various small businesses in the fields of convection, food production, bakery, and more. In order to operate legally, these businesses require several permits, such as the Business Identification Number (NIB), which can be processed through the OSS RBA system. However, many MSME owners in Kebojongan Village lack knowledge regarding the importance and ease of registering for business permits, which hinders the formalization and growth of their businesses. The research aims to address this issue by increasing community awareness and skills related to the OSS system, thereby simplifying the business licensing process and fostering economic development in the village. With the NIB, MSMEs can easily obtain other essential permits, including business legality certifications, Indonesian National Standards (SNI), and Halal Product Guarantee Certificates. The service activities include interviews, counseling, mentoring, and evaluations on the use of OSS RBA and NIB registration, focusing on overcoming challenges such as forgotten passwords or registration errors. This service intervention aims to improve the adoption of the OSS system, enabling MSMEs in Kebojongan Village to complete the necessary licensing process with ease, supporting their growth and contributing to local economic development. By enhancing understanding and accessibility of the OSS platform, this initiative hopes to facilitate the accelerated development of business licensing for micro-enterprises in Kebojongan Village.
Unlocking Village Potential: Empowering Tanuharjo Officials to Boost Revenue through Village-Owned Enterprises
Authors: Sumarto Slamet , Martitah Martitah , Kristiono Natal , Hidayat Arif , Putra Tegar Islami
Published: February 2025

This study examines the optimization of the role of Tanuharjo Village officials in increasing village revenue through the establishment and management of Village-Owned Enterprises (BUMDes). The creation of BUMDes in Tanuharjo Village has proven to be a strategic initiative to maximize village potential and enhance local economic development. This article provides an overview of the service activities that have been carried out, focusing on the critical role of Tanuharjo Village officials in optimizing village income through the establishment, management, and active participation in BUMDes. The BUMDes has played a vital role in creating new jobs, boosting the productivity of key village sectors, and strengthening the local economy. Additionally, BUMDes serves as a platform for encouraging innovation and the entrepreneurial spirit within the village community. Through one-way counseling sessions organized by the Semarang State University service team, the capacity of Tanuharjo Village officials in BUMDes management has been significantly enhanced. The strategies implemented during these activities included the development of new business units by optimizing village resources, the creation of management training programs to improve BUMDes governance, and digital marketing training for human resources. These efforts have successfully increased the understanding and capabilities of village officials, contributing to improved performance in managing BUMDes and increasing village revenue. This service activity has provided practical recommendations for improving BUMDes governance, which are expected to stimulate further economic growth and improve the welfare of the community in Tanuharjo Village.
Empowering the Next Generation: Bold Strategies to Combat Corruption and Foster Integrity Among Youth
Authors: Prakasa Satria Unggul Wicaksana , Fatmawati Ida Nuriya
Published: February 2025

Corruption remains a significant barrier to social, political, and economic progress globally, and the role of youth in shaping a more transparent and ethical society is crucial. This study explores effective strategies to combat corruption and instill values of integrity among young people. The research highlights the importance of anti-corruption education as a key strategy in overcoming corruption and building integrity. A collaborative effort between the Muhammadiyah Youth Branch Leader of Krembangan Branch and the Faculty of Law, University of Muhammadiyah Surabaya has led to the implementation of an anti-corruption education program in Morokrembangan Village. The primary goal of this initiative is to raise awareness, enhance knowledge, develop skills, and foster concrete actions among youth to actively fight corruption. The collaboration between youth, local government, and civil society is fundamental to the program's success, positioning it as a pioneering effort to combat corruption and build integrity at the grassroots level. The program is designed to provide participants with an in-depth understanding of the dangers of corruption and the importance of integrity in daily life. It equips youth with the practical knowledge and skills needed to recognize, report, and prevent corruption. Additionally, by involving youth in the oversight of development projects and promoting transparent community services, the program seeks to inspire similar initiatives in other regions. The study concludes by emphasizing that empowering youth through education, advocacy, and active participation is key to fostering a future generation committed to transparency, integrity, and accountability.
Escalation of Community Legal Literacy in Resolving Land Disputes in Bumiaji Village, Batu City
Authors: Nuryasinta Radhityas Kharisma , Puspitasari Wardoyo Yohana
Published: February 2025

Land disputes are a significant issue in Bumiaji Village, Batu City, East Java, due to the community's low legal literacy and limited involvement of local stakeholders. Lack of understanding of formal legal procedures, the importance of land certification, and disharmony between customary and national laws have made it difficult to resolve land conflicts. This research aims to improve community legal literacy by considering the local context and strengthening the involvement of local stakeholders in land dispute resolution. The method used was Participatory Action Research (PAR), which actively involved communities and local stakeholders in problem identification, program design, and evaluation. The results showed that a locally-based approach that integrates customary and national laws was successful in improving community understanding of their legal rights and obligations, as well as encouraging participation in formal dispute resolution. In addition, the involvement of village officials, traditional leaders, and the National Land Agency in the dispute resolution process was able to create a more inclusive and equitable solution. The research concludes that legal literacy and synergy between local actors are key to resolving land disputes effectively and sustainably.
Realizing Political Leadership with Integrity Through Political Education: A Study of KOMPAK-API
Authors: Maskur Muhammad Azil , Fikri Wildan Azkal , Indraswara Dede
Published: February 2025

Political leadership with integrity is a must in realizing a golden Indonesia. However, corruption then becomes something that hinders leadership with integrity. Because of this, this study was conducted by the Anti-Corruption Counselor Community Forum-Integrity Building Experts (KOMPAK-API) which focuses on the realization of leadership with integrity through political education. This study raises the formulation of the problem in the form of What is the role of KOMPAK-API in conducting political education in Central Java? How can political education lead to the birth of political leadership with integrity? The study was conducted using a qualitative-descriptive method and found answers regarding the close relationship between political education carried out by KOMPAK-API and political leadership with integrity in Central Java. Political education is carried out at elementary school, high school, and university levels. Not only for students but also for all teachers. Based on this, political education is recognized as being able to realize political leadership with integrity in order to achieve a Golden Indonesia in 2045.
Metaverse as the Solution to the Absence of a Constitutional Court Moot Courtroom in Universities
Authors: Hidayah Nur Putri , Wicaksono Galih Wasis , Amiludin Amiludin , Al Sakinata Annisa' , Arcelia Allysa Sonia , Andesti Kiki , Muafika Siti Nurmala Lailatul , Saleha Meisya Maulidina
Published: February 2025

Courses related to procedural law are practicum courses with Course Learning Outcomes (CLO)/ Capaian Pembelajaran Mata Kuliah (CPMK) students who can simulate trials in court. In this case, the moot courtroom's urgency is to provide an infrastructure for students to conduct moot trials. One of the practicum courses is the Constitutional Court's Judicial Procedural Law. Students who take this course must be competent and able to practice in the objective realm of justice. However, based on the observation and tracing results, the service activities' partners do not have a moot courtroom in the constitutional court, so they cannot carry out moot court in the course. Digital/virtual space, known as Metaverse, is a solution for procuring infrastructure for the constitutional court's moot courtroom. The results of this service show that the Metaverse Moot Court of the Constitutional Court is an appropriate technology-based product that is the only quick solution to the absence and limitations of the Constitutional Court's moot courtroom at Partner universities. Partners do not need to spend millions to billions of Rupiahs to procure facilities and infrastructure for the Constitutional Court's moot courtroom. In addition, this product is a solution to time constraints, considering that the campus has operational hours while students are still required to be proficient in practicing proceedings at the Constitutional Court. Finally, the virtual reality technology product implemented in this pseudo-courtroom provides an immersive experience like the real atmosphere in the courtroom. It makes students more excited and increases motivation to practice the trial.
Mast Cells as a Factor in Regulation of Breast Cancer Stromal Component Associated with Breast Cancer Aggressiveness
Authors: MUSHII O. , PAVLOVA A. , BAZAS V. , BORIKUN T. , LUKIANOVA N.
Published: February 2025

Background. It has been proven that changes in the morphology, representation, and organization of collagen fibers contribute to the formation of a unique microenvironment, which is associated with the metastatic potential of malignant neoplasms due to the initiation of cell migration and changes in polarization. Among the modulators of the collagen stroma, fibroblasts remain the most widely studied today. At the same time, much less attention is focused on the study of immune cells in the tumor microenvironment, in particular, mast cells (MCs). Aim. To investigate the relationship between the MCs status and the features of the collagen matrix of breast cancer (BCa). Materials and Methods. The study was conducted on the postoperative material of 78 patients with BCa stage I—II. MCs were assessed by a histochemical method using toluidine blue. For estimation of the functional activity of MCs, a degranulation index was calculated. COL1A1, COL3A1, and MMP-9 expression in tumor tissue was assessed immunohistochemically. A visualization of collagen fibers was performed using the staining by Malory. Microphotographs were pre-processed in Adobe Photoshop SS 2019 and analyzed using the software packages CurveAlign v. 4.0 and ImageJ. Results. Tumor tissue with a high density and functional activity of MCs was characterized by an increased expression of COL1A1 (p < 0.05), COL3A1 (p < 0.05), and MMP-9 (p < 0.05). In BCa tissue with the lower MCs degranulation index, collagen fibers become thicker (p < 0.05), shorter (p < 0.05), and denser (p < 0.05). At the same time, the existence of a relationship between the levels of miR-155-5p and the expression of COL1A1 (r = 0.703, p = 0.009), COL3A1 (r = 0.603, p = 0.043), and MMP-9 in tumor cells (r = 0.562, p = 0.039) and in the stroma (r = 0.546, p = 0.038), as well as the associations of the levels of this miRNA with the fiber length (r = –0.632, p = 0.013), width (r = –0.522, p = 0.048), and density (r = 0.699, p = 0.014) were found. Significantly higher rates of miR-155-5p expression (p < 0.05) were recorded in BCa tissue with a high index of MCs degranulation. Conclusion. During the BCa progression, the role of MCs in the manifestation of the tumor development increases. A growing number of infiltrated MCs contributes to the activation of MMP and fibrillar collagen expression. These changes lead to increased remodeling of the tumor stroma, which is directly reflected in the spatial organization of the collagen matrix. The increased activity of proteases causes a decrease in the length and width of fibrils, which is explained by a decrease in the number of mature fibers and their disorganization in three-dimensional space. The obtained data allow us to assert that MCs play a key role not only in the formation of a specific immune microenvironment of BCa but also in determining the direction of changes in the tumor stroma, which promotes cancer aggressiveness.
First-order logics with partial predicates for checking variable definedness
Authors:   Kiev Taras Shevchenko National University, Shkilniak S.S.
Published: February 2025

We study semantic properties of new classes of program-oriented logics of partial quasiary predicates without monotonicity restriction. A feature of these logics is the use of special 0-ary parametric compositions – partial predicates which checks whether a subject name (variable) has a value in a given data. Such predicates-indicators are needed for quantifier elimination: from formulas of the form x we come to formulas of the form To perform such elimination in logics of non-monotonic predicates, the condition of definedness of a name z is needed, meaning a component with the name zis contained in the input data. We propose two types of pure first-order logics with partial predicates-indicators: LQ and LQ. Logics LQ use extended renominations, while LQ use traditional renominations. In this paper we describe composition algebras and languages of these logics, and introduce and investigate logical consequence relations for formulas and sets of formulas of the language: irrefutability (IR), truth (T), falsity (F) and strong (TF) logical consequences. Conditions that guarantee the logical consequence relation are considered, and their main properties are specified. Special attention is paid to the properties related to predicates-indicators and quantifier elimination. Logical consequence relations’ properties are the semantic basis for sequent calculi’s construction. Basic properties of a given logical consequence relation induce respective sequent forms for the corresponding calculus; properties that guarantee the logical consequence relation induce closedness conditions for sequents in this calculus. Construction of such sequent calculi is planned in the future works.
Nonlinearity and Controllability of Dielectric Permittivity
Authors: Voronov S.O. , Poplavko Yu.M.
Published: February 2025

Among the various materials used in electronics, an important place is occupied by the functional (smart) dielectrics. In this paper, we study dielectric nonlinearity and the possibility of an electrical control over the permittivity. In ionic compounds, this nonlinearity is conditioned by different electronegativities of neighboring ions, while the controllability of permittivity is determined by a change in the rigidity of atomic bonds under a controlling electric field influence. The relevance of this problem is due to the fact that microelectronics uses very thin dielectric layers, in which the electrical strength increases significantly allowing the use of nonlinearity. Moreover, in ferroelectrics, the electric field activates the orientation of domains, which significantly increases the permittivity, and, conversely, decreases it, when the reorientation of domains is suppressed by a bias electric field. The rate of nonlinear change in permittivity and its electrical control are important for use in electronics. So, the applicability limits of these properties are assessed using dielectric spectroscopy.
Overview of ATLAS Forward Proton Detectors: Status, Performance and New Physics Results
Authors: Sopczak A.
Published: February 2025

A key focus of the physics program at the LHC is the study of head-on proton-proton collisions. However, an important class of physics can be studied for cases where the protons narrowly miss one another and remain intact. In such cases, the electromagnetic fields surrounding the protons can interact producing high-energy photon-photon collisions. Alternatively, interactions mediated by the strong force can also result in intact forward scattered protons, providing probes of quantum chromodynamics (QCD). In order to aid identification and provide unique information about these rare interactions, the instrumentation to detect and measure protons scattered through very small angles is installed in the beam pipe far downstream of the interaction point. We describe the ATLAS Forward Proton ‘Roman Pot’ detectors (AFP and ALFA), their performance of Tracking and Time-of-Flight detectors, and first results.
His Bundle Pacing in the Era of Left Bundle Branch Pacing
Authors: Jastrzębski Marek , Huang Weijian , Vazquez Pablo Moriña , Vijayaraman Pugazhendhi
Published: February 2025

Soon after the rapid growth of the popularity of His bundle pacing (HBP), the use of this conduction system pacing modality was overshadowed by left bundle branch area pacing (LBBAP). This focused review on HBP addresses whether there are any advantages of HBP over LBBAP and what the current uses of HBP may be. We conclude that HBP must be considered as an alternative physiological pacing method with several potential applications, undoubtedly at least as a rescue option for failed CRT/LBBAP. For wider application of HBP, prospective studies are needed to document a reduction in the incidence of late threshold rise with modern implantation techniques. Nevertheless, HBP should be available in every modern pacing laboratory. This requires an active HBP program to maintain and develop the ability of operators to deliver HBP when it is most needed.
Lepanthes chalalensis (Pleurothallidinae), a new species endemic to the Santander department in Colombia
Authors: Parra-Sánchez Edicson , Restrepo Eugenio , Barrera Yadir , Ordóñez-Blanco Juan Camilo , Edwards David
Published: February 2025

We propose Lepanthes chalalensis as a newly identified species confined to the north-east Andes of Colombia. We randomly placed 341 sampling plots across the Eastern Cordillera, including transformed and natural habitats. Here, we provide a detailed description, illustrating images, ecological discussions, a taxonomic key for the new entity, and a conservation status analysis. The species is highly geographically restricted (in 2 out of 341 sampling plots) and has a low population size (26 adult individuals). While L. chalalensis shows a resemblance to L. velosa from Ecuador, it can be distinguished by the wide lower lobe of the petals, which is long ciliated, the lip laminae, which are reduced and bear stiff cilia, and the appendix length, which appear to be twice as long as the lip blades. The species should be considered a conservation concern due to its high rarity.
A new species of Dendrobium sect. Crinifera (Dendrobieae) from Thailand
Authors: Pedersen Henrik Æ. , Suddee Somran
Published: February 2025

A new species of Dendrobium sect. Crinifera is described from Thailand. The late Peter O’Byrne is appropriately credited for his important preparatory work for our study and for coining the name of the new species, D. krabiense. Apparently endemic to southern Thailand, D. krabiense is similar to D. pardalinum but differs in the lip mid-lobe being distinctly clawed and in the lip ornaments only consisting of two lateral keels that extend from near lip base to claw of mid-lobe. Dendrobium krabiense is also similar to D. phuketense but differs in having larger, spotted flowers with a proportionally longer mentum. The material here referred to D. krabiense was previously misidentified as Flickingeria pallens (now considered a synonym of D. pardalinum).