bluuebunny/crossref_metadata_2025 huggingface dataset:
Bilateral Economic Cooperation between Kazakhstan and Central Asian Countries
Authors: Dodonov V.
Published: August 2023

The article analyzes the trends in economic cooperation between Kazakhstan and the four states of post-Soviet Central Asia in the main areas, as well as the current situation. Mutual trade in goods and services, investment cooperation and joint entrepreneurship are considered. The analysis carried out demonstrates the unevenness of economic ties with individual states of the region, their lower intensity compared to aggregate indicators in the long term, but significant acceleration over the past decade, which makes it possible to predict an increase in the intensity of cooperation in the medium term.
Turkmenistan: The Son Continues the Father’s Policy
Authors: Potapova E.
Published: August 2023

On March 19, 2022, Serdar Berdimuhamedow succeeded his father, Gurbanguly Berdimuhamedow, as president. However, no significant changes have taken place in Turkmenistan so far during his presidency: the authoritarian regime continues, there is no freedom of speech, and human rights are not protected. The country remains closed and isolated from the international community. Meanwhile, the ex-president has not weakened his political influence at all and fully controls the activities of his son.
The Adoption of a Big Data Approach Using Machine Learning to Predict Bidding Behavior in Procurement Management for a Construction Project
Authors: Kusonkhum Wuttipong , Srinavin Korb , Chaitongrat Tanayut
Published: August 2023

Big data technologies are disruptive technologies that affect every business, including those in the construction industry. The Thai government has also been affected, and attempted to use machine learning techniques with the analytics of big data technologies to predict which construction projects have a winning price over the project budget. However, this technology was never developed, and the government did not implement it because they had data obtained via a traditional data collection process. In this study, traditional data were processed to predict behavior in Thai government construction projects using a machine learning model. The data were collected from the government procurement system in 2019. There were seven input data, including project owner department, type of construction project, bidding method, project duration, project level, winning price over estimated price, and winning price over budget. A range of classification techniques, including an artificial neural network (ANN), a decision tree (DC), and K-nearest neighbor (KNN), were used in this study (ANN). According to the results, after hyperparameter tuning, ANN had the greatest prediction accuracy with 78.9 percent. This study confirms that data from the Thai government procurement system can be investigated using machine learning techniques from big data technologies.
Music Listening as Kangaroo Mother Care: From Skin-To-Skin Contact to Being Touched by the Music
Authors: Reybrouck Mark
Published: August 2023

The metaphor of being touched by music is widespread and almost universal. The tactile experience, moreover, has received growing interest in recent years. There is, however, a need to go beyond a mere metaphorical use of the term, by positioning the tactile experience within the broader frame of embodied cognition and the experiential turn in cognitive science. This article explores the possible contribution of a science of touch by defining music as a vibrational art that impinges upon the body and the senses. It takes as a starting point the clinical findings on the psychological and physiological value of tender touch with a special focus on the method of kangaroo mother care, which is a method for holding the baby against the chest of the mother, skin-to-skin. It is seen as one of the most basic affiliative bonding with stimuli that elicit reward. Via an extensive review of the research literature, it is questioned to what extent this rationale can be translated to the realm of music. There are, in fact, many analogies, but a comprehensive theoretical framework is still lacking. This article aims at providing at least some preparatory groundwork to fuel more theorizing about listening and its relation to the sense of touch.
DEVELOPING A PATIENT-CENTERED COMMUNITY-BASED MODEL FOR MANAGEMENT OF DRUG RESISTANT TUBERCULOSIS IN RURAL EASTERN CAPE: A COLLABORATIVE APPROACH OF HEALTH CARE FACILITIES, DIAGNOSTIC LABORATORIES AND RESEARCH INSTITUTIONS
Authors: FAYE LINDIWE MODEST , Bokop Carine , Vasaikar Sandeep , Apalata Teke , Dlatu Ntandazo
Published: August 2023

Infectious illnesses have always posed a threat to human health, with tuberculosis (TB) being a major concern. The use of various medications and antibiotics in the fight against such illnesses has led to the emergence of drug-resistant infectious diseases, which have become increasingly dif-ficult to manage as medical and scientific research has advanced. Inadequate medical infrastruc-ture, incorrect treatment practices that exacerbate resistance patterns, and transmission within communities and healthcare facilities are the main factors contributing to the spread of drug-resistant TB. Though treating individuals with multiple drug resistance (MDR) and extreme drug resistance (XDR) strains is challenging, early identification of resistance and the imple-mentation of a well-designed treatment regimen can result in a cure. Community-based inter-ventions that address socioeconomic barriers to adherence can also enhance treatment outcomes. While there have been few studies and proposed conceptual models on how to manage and prevent various drug-resistant TB mutations and lineages, a model aimed at limiting and controlling such mutations has been developed. This paradigm seeks to bridge the gap by facilitating the exchange of knowledge among healthcare professionals (HCP) in healthcare facilities (HCF), diagnostic laboratories (DL), and research institutes (RI), particularly for underprivileged communities in the Eastern Cape. The model guide will also monitor and evaluate TB management plans
Electromagnetic conversion into kinetic and thermal energies
Authors: Brandenburg Axel , Protiti Nousaba Nasrin
Published: August 2023

Conversion of electromagnetic energy into magnetohydrodynamic energy occurs when the electric conductivity changes from negligible to finite values. This process is relevant during the epoch of reheating of the early Universe at the end of inflation and before the emergence of the radiation-dominated era. We find that conversion into kinetic and thermal energies is primarily the result of electric energy dissipation and that the magnetic energy plays only a secondary role in this process. This means that, since electric energy dominates over magnetic energy during inflation and reheating, significant amounts of electric energy can be converted into magnetohydrodynamic energy when conductivity emerges early enough, before the relevant length scales become stable.
Evaluation of Antiviral Compounds from Commiphora molmol Myrrh Resin and Their Promising Application with Biochar
Authors: Kim Jin Woo , Park Saerom , Sung Young Whan , Song Hak Jin , Yang Sung Woo , Han Jiwoo , Jo Jeong Wook , Lee Im-Soon , Lee Sang Hyun , Choi Yong-Keun , Kim Hyung Joo
Published: August 2023

Commiphora molmol myrrh resin extracts, which have different physical properties such as polarity and dielectric constant, were prepared by immersion in extraction solvents (hot water, DMSO, hexane, ethanol, and methanol). Methanolic myrrh resin extracts showed broad antibacterial activity against isolated airborne bacteria. Furanoeudesma-1,3-diene and curzerene, as the main terpenoids in the methanolic myrrh resin extract, were analyzed using GC-MS, and the methanolic myrrh resin extracts were found to have antiviral activity (81.2% viral RNA inhibition) against H1N1 influenza virus. Biochars (wood powder-and rice husk-derived) coated with myrrh resin extracts also showed antiviral activity (22.6% and 24.3% viral RNA inhibition), due to the adsorption of terpenoids onto biochar. Myrrh resin extract using methanol as the extraction solvent is a promising agent with antibacterial and antiviral efficacy, and it can be utilized as a novel material via adsorption onto biochar for air filtration processes, cosmetics, fertilizers, drug delivery, and corrosion inhibition.
Chemical Composition of Scaptotrigona mexicana Honey and Propolis Collected in Two Locations: Similarities and Differences
Authors: Gerginova Dessislava , Popova Milena , Chimshirova Ralitsa , Trusheva Boryana , Shanahan Maggie , Guzmán MIguel , Solorzano-Gordillo Eric , López-Roblero Estefhanía , Spivak Marla , Simova Svetlana , Bankova Vassya
Published: August 2023

The chemical composition of stingless bee honey and propolis depends on the plant sources they are derived from, and thus reflects the flora available in the vicinity of the hives, the preference of the bee species, and the climate (altitude and temperature). To understand the relative influence of these factors, we studied the composition of honey and propolis. Samples from 24 colonies were analyzed: 12 from each of two Scaptotrigona mexicana meliponiaries located in the state of Chiapas in southern Mexico approximately 8.5 km apart. The chemical composition of honey and propolis was studied using NMR, and GC-MS, respectively. Antioxidant activity of propolis was also studied. Chemometric analyses were applied. The Tuxtla Chico honey samples contained higher concentrations of glucose and fructose, while the Cacahoatán samples displayed a rich composition of di- and trisaccharides. These differences can be attributed to the distinct nectar sources utilized by the bees in each location. Propolis composition in the two locations also demonstrated qualitative differences, indicating a specific choice of resins by the bees. The observed substantial variations in the chemical composition of propolis and honey of S. mexicana from two relatively close locations support the assumption that bee species cannot be regarded as the most important factor determining their chemistry.
Arboviral Risk Associated with Solid Organ and Hematopoietic Stem Cell Grafts: The Prophylactic Answers Proposed by the French High Council of Public Health in a National Context
Authors: Pozzetto Bruno , Grard Gilda , Durand Guillaume , Paty Marie-Claire , Gallian Pierre , Lucas-Samuel Sophie , Diéterlé Stéphanie , Fromage Muriel , Durand Marc , Lepelletier Didier , Chidiac Christian , Hoen Bruno , Nicolas de Lamballerie Xavier
Published: August 2023

Diseases caused by arboviruses are on the increase worldwide. In addition to arthropod bites, most arboviruses can be transmitted via accessory routes. Products of human origin (labile blood products, solid organs, hematopoietic stem cells, tissues) present a risk of contamination for the recipient if the donation is made when the donor is viremic. This narrative review describes the risks of acquiring certain arboviral diseases from human products, mainly solid organs and hematopoietic stem cells, in the French context. Mainland France and its overseas territories are exposed to a complex array of imported and endemic arboviruses, which differ according to their respective location. The main risks considered in this study are infections by West Nile virus, dengue virus and tick-borne encephalitis virus. The ancillary risks represented by Usutu virus infection, chikungunya and Zika are also addressed more briefly. For each disease, the guidelines issued by the French High Council of Public Health, which is responsible for issuing guidelines to mitigate the risks associated with products of human origin and for supporting public health policy decisions, are briefly outlined. The aim of this review is also to contribute to the standardization of recommendations at international level in areas with the same viral epidemiology.
Hydropower Advantages over Batteries in Energy Storage of Off-Grid Systems
Authors: G Prajwal Shandilya M , Quaranta Emanuele , Coronado-Hernández Oscar E. , Ramos Helena M.
Published: August 2023

: There has been an ever-increasing demand for energy from the past decades. Renewable energy technologies play a major role in satisfying the energy demand as well as in a decreased CO2 emissions. Solar and Wind energies are the major upcoming technologies in renewable energies. Decentralized power production is a system where the energy production and consumption are very close to each other. Microgrids can be decentralized or grid connected and they, with renewable energy sources, encounter a problem of storage as the power production from solar and wind is intermittent. This paper discusses the comparison between using batteries and pumped storage hydropower (PSH) as an energy storage system and the integration of wind and solar PV energy sources. HOMER software simulations are used to obtain optimized renewable energy integration in microgrid and to understand its economic analysis. Two scenarios are run with the model where one considers battery and the other considers PSH to obtain the economic and technical best results of these microgrids. The economic analysis showed a lower net present cost (NPC) and levelized cost of energy (LCOE) for the microgrid with PSH. The results show that microgrid with storage of PSH is economical with an NPC of 45.8 M€ and an LCOE of 0.379 €/kWh in comparison with batteries solution which has an NPC of 95.2M€ and an LCOE of 0.786 €/kWh. The role of storage is understood by differentiating the data into different seasons using Python for data analysis. Furthermore, sensitivity analysis is made by varying the capital cost multiplier of Solar PV and Wind Turbine to obtain optimal solutions.
Vision impairments in young adults with Down syndrome
Authors: Martin-Perez Yolanda , Gonalez-Montero Guadalupe , Gutierrez-Hernandez Angel Luis , Blázquez-Sánchez Vanesa , Sánchez-Ramos Celia
Published: August 2023

People with Down syndrome have more visual problems than general population. They experience a premature aging, and it would be expected they will also have an acceleration in worsening visual function. A prospective observational study which includes visual acuity, refractive error, accommodation, binocular and colour vision was performed to young adults with (n=69) and without (n=65) Down syndrome and to a senior group (n=55) without Down syndrome. Results showed significant differences in visual acuity between groups (p<0.001) and it can be improved with a new prescription in 40% of the participants with Down syndrome. Regarding to accommodative state, no significant differences were found between groups of young people. Concerning binocular vision, 64.7% of strabismus was observed in the group with Down syndrome (p<0.001). Visual abnormalities are significant in young adults with Down syndrome and are different from those of older people without Down syndrome, some of which can be improved by providing the optimal prescription as well as regular eye examinations.
Diagnostic Roles of Immunohistochemical Markers, CK20, CD44, AMACR, and p53 in Urothelial Carcinoma In Situ: A Meta-Analysis and Diagnostic Test Accuracy Review
Authors: Yoo Daeseon , Min Kyueng-Whan , Pyo Jung-Soo , Kim Nae Yu
Published: August 2023

This study aimed to evaluate the diagnostic roles of various immunohistochemical markers in urothelial carcinoma in situ (uCIS) through a meta-analysis and review of diagnostic test accuracy. Immunohistochemical markers CK20, CD44, AMACR, and p53 were evaluated in the present study. We analyzed the expression rates of immunohistochemical markers and compared their diagnostic accuracies. The estimated expression rates were 0.803 (95% confidence interval [CI]: 0.726–0.862), 0.142 (95% CI: 0.033–0.449), 0.824 (95% CI: 0.720–0.895), and 0.600 (95% CI: 0.510–0.683) for CK20, CD44, AMACR, and p53, respectively. In the comparison between uCIS and reactive/normal urothelium, the expression of CK20, AMACR, and p53 in uCIS was significantly higher than in reactive/normal urothelium. CD44 showed significantly lower expression in uCIS than in the reactive/normal urothelium. Among the markers, AMACR had the highest sensitivity, specificity, and diagnostic odds ratio. The AUC on SROC was the highest for CK20. In conclusion, immunohistochemical markers, such as CK20, CD44, AMACR, and p53, can be useful in differentiating uCIS from reactive/normal urothelium.
Sustainability Reporting and Climate Change Energy Requirements: The Role of Companies and Their Governance - A Review
Authors: Madaleno Mara , Vieira Elisabete , Magueta Daniel , Nogueira Manuel
Published: August 2023

The perceived poor performance of publicly traded companies on their sustainability commitments and the quality of sustainability reporting has prompted stakeholders to consider the economic, environmental, and social impacts of corporate activities. Economic activities have led to various threats in the form of climate change, pollution, greenhouse gas emissions, natural disasters, and other issues that have negatively impacted the environment and stakeholders. Companies are expected to report to stakeholders on their sustainability performance, but reality proves that present reporting falls below stakeholders’ expectations mainly due to its still voluntary nature. The present study aims to provide a literature review of the relationship between sustainability reporting and the role of companies governance, especially observing if climate change requirements and energy-needed changes are being accounted. Results highlight mixed evidence for the influence of board governance attributes, providing interesting insights for research advancement. The study has practical implications for businesses, regulators, governments, and other stakeholders in their policy deliberations and investment decisions. Further empirical studies are recommended to re-examine sustainability reporting using the variables identified as important factors and gaps in this study and other board characteristics to improve the generalizability of the results.
ALGORITHM FOR RECOGNITION TECHNOLOGY OF ACOUSTIC SIGNALS
Authors: Vasin Pavlo
Published: August 2023

An algorithm for processing the reflected acoustic signal for the technology of object recognition against the background of noise interference is presented. The considered mathematical model takes into account that the input data (acoustic signals) have a previously unknown probability distribution. To build an acoustic signal processing technology the Markov chain based probabilistic models, the Monte Carlo integration method and the Bootstrap filter method built on it were used. Based on them, an algorithm for processing an acoustic signal reflected from obstacles was created. The signal processing technology implements the transition from the input data to the representation of the input data in the form of a grid, where a characteristic-intensity normally distributed according to the central limit theorem is assigned to each cell. A likelihood function is used to detect noise at a random point. The algorithm is ready for practical use, which is confirmed by examples. The result of the algorithm application for the recognition of two moving objects, which have a reflected acoustic signal close to the noise, is graphically presented. The dependence of the processing speed on the amount of data is noted. Several constructive approaches to solving this problem are given. It is noted that by using the methods of storing sparse matrices the estimate of the memory used is reduced from quadratic to linear with deterioration of the speed estimate by a logarithm.
BUDGET PARTICIPATION: INTERACTION EFFECTS OF WORK ENGAGEMENT AND EMPOWERMENT
Authors:   University of Edinburgh Business School, Chia Yew Ming , GRANT Lewis ,   Johnston Carmichael LLP
Published: August 2023

This study investigates the two-way interaction effects of work engagement and empowerment on the degree of employees' budget participation industry in Scotland. Data are collected from 159 employees via an online questionnaire and analyzed using multiplicative regression analysis. The results confirm the presence of a two-way interaction effect between work engagement and empowerment on the degree of budget participation at a statistically significance level (p = 0.0002). Further analysis indicates that the higher the empowerment, the greater its enhancing effect on the positive relationship between work engagement and the degree of employees' budget participation. This study provides one of the first empirical evidence of a contingent relationship between work engagement and budget participation over the range of the level of empowerment. Consequently, the results have contributed insights to the literature in facilitating our understanding of both the moderating role of empowerment and extending the boundary conditions on work engagement and budget participation association. Human resource personnel and management can consider the application of empowerment as a potential intervention strategy to boost the productivity and performance of employees resulting from the latter's increased participation in the budget-setting process.
Novel insight in Lepidoptera phylogenetics from the mitochondrial genome of the apple fruit moth of the family Argyresthiidae
Authors: Elameen Abdelhameed , Maduna Simo N. , Mageroy Melissa H. , Eerde Andre van , Knudsen Geir , Hagen Snorre B. , Eiken Hans Geir
Published: August 2023

Background The order Lepidoptera has an abundance of species, including both agriculturally beneficial and detrimental insects. Based on molecular data, the phylogenetic relationships of the major subdivisions of Lepidoptera have been investigated, contributing to the understanding of the evolutionary relationships at the superfamily and family levels. However, the phylogenetic placement of many superfamilies and/or families in this order is still unknown. In this study, we determine the systematic status of the family Argyresthiidae within Lepidoptera and explore its phylogenetic affinities and implications for the evolution of the order. We describe the first mitochondrial (mt)genome from a member of Argyresthiidae, the apple fruit mothArgyresthia conjugella. The insect is an important pest on apples in Fennoscandia, as it switches hosts when the main host fails to produce crops. Results The mt genome ofA. conjugellacontains 16,044 bp and encodes all 37 genes generally found in insect mt genomes, including 13 protein-coding genes (PCGs), two ribosomal RNAs, 22 transfer RNAs, and a large control region (1101 bp). The nucleotide composition was extremely AT-rich (82%). All detected PCGs (13) began with an ATN codon and terminated with a TAA stop codon, except the start codon incox1is ATT. All 22 tRNAs had cloverleaf secondary structures, except tRNAS1, where one of the dihydrouridine (DHU) arms is missing, reflecting potential differences in gene expression. When compared to the mt genomes of 507 other Lepidoptera representing 18 superfamilies and 42 families, phylogenomic analyses found thatA. conjugellahad the closest relationship with the Plutellidae family (Yponomeutoidea-super family). We also detected a sister relationship between Yponomeutoidea and the superfamily Tineidae. Conclusions Our results underline the potential importance of mt genomes in comparative genomic analyses of Lepidoptera species and provide robust evolutionary insight across the tree of Lepidoptera species.
The student voice on integrative teaching and learning of academic literacy at a South African university of technology
Authors: TICHA IGNATIUS , Nakhooda Muhammad , OBI ULOMA
Published: August 2023

This study undertakes a detailed analysis of students' reflections to determine whether integrative learning and teaching of academic literacy improves students’ learning experience and adds value to the academic literacy course. The rationale for the study is that there is yet, no agreement at the selected institution on the most effective model for designing and teaching academic literacy courses. As such, many models exist, creating the need for ongoing inquiry on the appropriateness and value of the different models. Also, most studies give voice to lecturers rather than the students for whom the courses are designed. Following an empirical research conducted in a selected academic program at the University of Technology, students were interviewed. Questionnaires were administered to fifteen students, vis-a-vis their reflections on integrative learning and teaching. The findings revealed that integrative learning and teaching of academic literacy had value in the specific case, improving students’ learning experience, making disciplinary discourses more elicit and ensuring that literacy skills acquired were applied in the discipline or content areas.
Dietary carotenoid intake and fracture risk based on NHANES 2013- 2018 data: A propensity Score Matching
Authors: Charkos Tesfaye , Lemi Hunde , Oumer Kemal Sherefa
Published: August 2023

Introduction: Several epidemiological studies reported inconsistent findings on the association between carotenoid intake and fracture risk. This study aimed to determine the association between individual carotenoid intake with fracture risk.
Methods: A cross-sectional study based on data from the National Health and Nutrition Examination Survey (NHANES), 2013–2018. This study identified elderly individuals with valid and complete data on carotenoid intake and bone mineral density. The average of α-carotene, β-carotene, β-cryptoxanthin, lycopene, and lutein + zeaxanthin was taken based on the two 24-hour recall interviews. BMD was measured by dual-energy X-ray absorptiometry (DXA). Matching was done based on age, sex, and body mass index (BMI). Logistic regression models were used to test the associations between carotenoids and fracture risk All analyses were performed by using the R (Version: 3.4.3; R Foundation for Statistical Computing, Vienna, Austria)
Results: A total of 5491 (1140 cases and 4351 control) subjects were included in this study. The average age of the subjects was 55.62 ± 14.84 years old. In the adjusted model, The risk of osteoporotic fracture was decreased by 6.2% (OR: 0.938; 95%CI: 0.699 to 0.989) and 1.4% (OR 0.986; 95%CI: 0.975 to 0.997) for dietary intake of beta-carotene and lycopene respectively.
Conclusions: Dietary intakes of beta-carotene and lycopene have significantly reduced the risk of osteoporotic fracture among the elderly population in the United States of America.
Dynamic changes of soil microbial communities during the afforestation of Pinus armandii in a karst region of Southwest China
Authors: He Bin , Li Qing , Zou Shun , Bai Xiaolong , Li Wangjun
Published: August 2023

Purpose
Clarifying the response of soil microbial communities to vegetation restoration is essential to comprehend biogeochemical processes and ensure the long-term viability of forest development. Nonetheless, it remains uncertain how plants and soil influence microbial properties, particularly in ecologically vulnerable areas like the karst region.
Methods
To assess the variations in soil microbial communities throughout the growth of Pinus armandii plantations in the karst region, we utilized the "space instead of time" approach and selected four P. armandii stands with ages ranging from 10 to 47 years, along with a grassland control. The microbial community structure was determined by conducting Illumina sequencing of the 16S rRNA gene and the ITS gene, respectively.
Results
The results demonstrated that afforestation with P. armandii significantly influenced soil microbial communities, as indicated by notable differences in bacterial and fungal composition and diversity between the plantations and the control. However, soil microbe diversity did not display significant variation across stand ages. Moreover, the bacterial community exhibited higher responsiveness to age gradients compared to the fungal community. Soil physicochemical factors play a critical role in elucidating variations in microbial diversity and community composition during the restoration processes.
Conclusions
Overall, our findings indicate substantial changes in soil bacterial and fungal communities across successive stages of development. Additionally, the changes in dominant bacteria and fungi characteristics across the age gradient were primarily attributed to variations in the prevailing soil conditions and chemical factors.
Feasibility of bioremediation of iron-contaminated water using Trichonephila clavipes spider webs
Authors: Ruiz Valentina Martinez , Londoño Victoria Eugenia Pizza , SUAREZ Marisol GORDILLO , Rosero Javier Jurado
Published: August 2023

Heavy metals are of great environmental and sanitary importance due to the toxicity they generate, for this reason a wide variety of methods have been studied for their elimination in the water matrix. One of these methodologies is bioremediation, which consists of removing these elements using biomass (microorganisms or plants), live plants (phytoremediation) or biomaterials.
In this study, we investigated the technical feasibility of using the Trichonephila clavipes spider web as a biomaterial for iron removal in water by bioremediation. A bibliometric analysis was carried out, where the process variables and an experimental design were defined using the Response Surface Methodology (RSM), and the iron concentrations were measured before and after the experiment using X-ray fluorescence spectroscopy by dispersive energy (EDX). We obtained an iron removal of 91.82%, using 28.09 h, 81.42 ppm of iron and 0.062 g of spider web. This work is novel and presents a new methodology for the bioremediation of water contaminated with iron, using spider webs. The results indicate a high efficiency in the removal of iron, which could have important implications in solving environmental and health problems associated with the presence of heavy metals in water.
WITHDRAWN: CNN-NDOGSPM-CSVM: Advancing Image Feature Sparse Coding and Classification for Enhanced Recognition Performance
Authors: SHU Zhong
Published: August 2023

This paper introduces a novel approach, CNN-NDOGSPM-CSVM, for image feature sparse coding and classification. The algorithm combines the analysis of Scale Invariant Feature Transform-Sparse Coding-Spatial Pyramid Matching and Convolutional Neural Networks-Sparse Coding-Spatial Pyramid Matching algorithms with the principles of Support Vector Machines (SVM). The objective is to enhance convergence control, improve the performance of the pyramid space model (SPM), and optimize the CSVM classifier. In the N-DOG-SPM model, emphasis is placed on controlling image feature sparse coding convergence efficiency and achieving real-time updatable sparse coding. The algorithm constructs an operation function using iterative operation direction and gradient parameters. However, initial experiments reveal challenges in achieving ideal convergence control. To address this, the algorithm focuses on constraints for local sparse coding and accurate calculation of control parameters. The SPM is enhanced by expanding the weight distribution range of the learning dictionary and feature sparse coding operation. This improvement addresses the negative effects of sparse coding iteration and value, resulting in improved convergence control and classification results. In the CSVM classifier, traditional minimum value calculation through differential derivatives is replaced. Bayesian recurrence theory and clustering classification theory are employed, while image feature sparse coding of Gaussian distribution is re-described. Posterior probability operation rules are used to solve key direction vectors, improving real-time updating accuracy. Through comprehensive evaluation, the experimental results demonstrate that the proposed CNN-NDOGSPM-CSVM model exhibits high reliability, accuracy, stability, and superior processing efficiency compared to classical image recognition models. The algorithm's performance is assessed in terms of image feature extraction, feature classification, image recognition accuracy, and processing efficiency.
Device and Circuit-Level Performance Evaluation of DG-GNR-DMG Vertical Tunnel FET
Authors: Liana Zohming , Tripathy Manas Rajan , Choudhuri Bijit , Bhowmick Brinda
Published: August 2023

This work presents the comparative study of Graphene Nanoribbon (GNR) based channel Double Gate (DG) Dual Gate Material (DMG) Vertical tunnel FET performance with all Silicon material TFET. The two-dimensional material GNR has been proposed in the channel material to enhance the device performance due to its low bandgap, high mobility, and high saturation velocity. The proposed device's DC, RF, and circuit-level performance analysis has been carried out for the first time. GNR-based channel VTFET shows a better average subthreshold swing (SSAVG ) of 16 mV/decade compared to Si VTFET (36 mV/decade) at a drain voltage VDS=0.5 V. The study of temperature effects on the DC parameters is also included along with the analog/RF FOMs for the proposed two structures. In addition, the performances are compared with other reported works; it is observed that DG-GNR-DMG-VTFET offers better results than Si-based VTFET and other said TFET work. Finally, circuit-level analysis has been done by designing inverter and ring oscillator circuits for the proposed structures, and performance is compared in these two devices. The market-available Silvaco ATLAS TCAD simulator has been used for device-level simulation. Further, circuit-level analysis has been carried out in the Cadence Virtuoso tool using a look-up table-based Verilog-A model.
Accessible soliton solutions with initial phase-front curvature in strongly nonlocal nonlinear media
Authors: zhang shaohua , qu jun
Published: August 2023

Based on the extended fractional dimensional nonlinear Schrödinger equation and the variable separation method, a fractional accessible soliton solution with initial phase curvature is proposed for the first time. The soliton solution of the model is composed of hypergeometric functions and generalized Laguerre polynomials in fractional dimensional space, namely, Hypergeometric-Laguerre-Gaussian soliton. The theoretical results indicate that a series of different types of solitons are generated with the change of the beam parameters, forming a fractious family of solitons. At the same time, solitons produce a splitting phenomenon similar to that of the Hermitian beams. Additionally, the initial phase curvature also affects the stability of beam propagation, suppressing the formation of soliton.
Automotive air conditioning vent defect detection method based on improved yolov5
Authors: Zheng Gang , Xu HaiFu , Fu YongZhong , Kong Xiao , Qiu Liang
Published: August 2023

In response to the low efficiency and high miss rate in the manual quality inspection of automotive air vent trim rings by current automotive suppliers, this paper proposes an improved YOLOv5-based method for detecting defects in automotive air vent trim rings. Firstly, the Coordinate Attention(CA) is introduced into the network to improve the feature extraction capability of the network for defects in automotive air vent trim rings. Secondly, the Space-to-Depth(SPD) module is introduced for downsampling to reduce the loss of subtle features during the downsampling process, which is beneficial for improving the feature extraction of the network for trim ring defects. Finally, the detection head is replaced with a decoupling head to alleviate the conflict between the classification task and the regression task, thereby improving the defect detection rate. On a self-generated dataset of defects in automotive air conditioning vent trim rings, the improved network achieves a mean accuracy(mAP) of 93.6%, an accuracy of 91.3%, and a recall rate of 88. 9%. Compared with the original network, the precision is improved by 3.4%, the accuracy is improved by3.2%,and the recall rate is improved by 3%.The proposed method can achieve defect detection in automotive air conditioning vent trim rings, laying a foundation for building an automated quality inspection system for automotive air conditioning vent trim rings.
Response of Oxidative Stress and Neurotoxicity Biomarkers in Rainbow Trout (Oncorhynchus Mykiss) After Exposure to Six-Metal Mixtures
Authors: Nalivaikienė Reda , Kalcienė Virginija , Butrimavičienė Laura
Published: August 2023

The activity of liver catalase (CAT) and brain acetylcholinesterase (AChE) was assessed in rainbow trout (Oncorhynchus mykiss) after 7- and 14-day exposure to a six-metal mixture at the maximum permissible concentrations (MPC) accepted for inland waters in the EU (2013/39/EB; 2008/105/EB) (Zn – 0.1, Ni – 0.034, Cu – 0.01, Cr – 0.01, Cd – 0.0015 and Pb – 0.014 mg L-1) (Mix) and to the same six-metal mixtures with tenfold reduced concentration of Cu (Mix Cu↓) and Cr (Mix Cr↓) ions. A statistically significant increase of up to 26% of CAT and 52% of AChE activity was observed in rainbow trout after 7 days of exposure to the six-metal mixture at MPC in comparison to a control group. After 14 days of treatment, neither CAT nor AChE showed a significant response. Moreover, 7 and 14 days of exposure to the six-metal mixtures with the tenfold reduced concentrations of Cr or Cu ions did not significantly alter CAT activity. The six-metal mixture with the tenfold reduced concentration of Cr increased brain AChE activity in O. mykiss after 7 days of exposure (35%), but did not show a significant response in AChE activity in comparison to a control group after 14 days of treatment. After 7 and 14 days of exposure to the six-metal mixture with the tenfold reduced concentration of Cu ions, AChE activity did not vary significantly in comparison to control groups. Enhancement of catalase activity caused by the mixture of the six metals at MPC and the increased AChE activity in response to the same metal mixture and mixture with tenfold reduced Cr concentration after 7 days of exposure indicates the induction of oxidative stress and disturbance of cholinergic system homeostasis respectively.
Cell autonomous role of border associated macrophages in ApoE4 neurovascular dysfunction and susceptibility to white matter injury
Authors: Iadecola Costantino , Anfray Antoine , Schaeffer Samantha , Hattori Yorito , Santisteban Monica , Casey Nicole , Wang Gang , Strickland Michael , Zhou Ping , Holtzman David , Anrather Josef , Park Laibaik
Published: August 2023

Apolipoprotein-E4 (ApoE4), the strongest genetic risk factor for sporadic Alzheimer’s disease, is also a risk factor for microvascular pathologies leading to cognitive impairment, particularly subcortical white matter injury. These effects have been attributed to alterations in the regulation of the brain blood supply, but the cellular source of ApoE4 and the underlying mechanisms remain unclear. In mice expressing human ApoE3 or ApoE4 we report that border associated macrophages (BAM), myeloid cells closely apposed to neocortical microvessels, are both the source and the target of the ApoE4 mediating the neurovascular dysfunction through reactive oxygen species. ApoE4 in BAM is solely responsible for the increased susceptibility to oligemic white matter damage in ApoE4 mice and is sufficient to enhance damage in ApoE3 mice. The data unveil a new aspect of BAM pathobiology and highlight a previously unrecognized cell autonomous role of BAM in the neurovascular dysfunction of ApoE4 with potential therapeutic implications.
Experiência de um Hospital Terciário no Tratamento de Fraturas do Úmero
Authors: Barreto Hemanuelli Samia de Aguiar , Thibério Willer Fellipe , Di-Sicco Rodrigo Delfino , De-Castro Gustavo Concon , Rezende Luis Guilherme Rosifini Alves , Mazzer Nilton
Published: August 2023

Introdução: As fraturas do úmero apresentam diferentes mecanismos de trauma sendo distribuídas de acordo com o nível de complexidade das lesões associadas. Estes fatores incluem o padrão de cominuição óssea, personalidade da fratura e lesões de partes moles, como lesões de estruturas neurovasculares e falhas de cobertura cutânea. O objetivo deste estudo é apresentar a complexidade das fraturas do úmero em um hospital de nível terciário e as alternativas escolhidas para o seu manejo. Métodos: Estudo retrospectivo, baseado em dados de prontuário de pacientes submetidos a tratamento cirúrgico de fraturas do úmero no período de janeiro de 2017 a dezembro de 2022 em um hospital terciário. Resultados: Observamos uma tendência em indivíduos do sexo masculino (p=0,059), maior para fraturas da diáfise do úmero, com diferença estatística para idade (p=0,01) com 42 anos em homens e 53 anos em mulheres. Não houve diferença estatística para a gravidade das Fraturas no úmero proximal (p=0,365), com diferença estatística na complexidade de fraturas da porção distal (p=0,001). O tempo médio até o tratamento definitivo foi de 12 dias, com influência no ponto de corte para complicações (p=0,02). A taxa global de reoperação foi de 18,7%, maior nos casos de úmero proximal e distal devido a infecção. Houve diferença estatística para lesão do nervo radial em fraturas diafisárias (p=0,001). Conclusão: nossos resultados corroboram achados na literatura com discretas alterações no padrão de distribuição epidemiológico e no padrão de complicações, contudo, observamos que o tempo para osteossíntese definitiva pode influenciar nos resultados, apesar de o mesmo depender de estabilização clínica e de partes moles do paciente. Contudo, mais estudos são necessários com grupos de controle.
Features of myocardial characteristics of patients with acute ST-segment elevation myocardial infarction with diabetes mellitus as assessed by contrast-enhanced cardiac magnetic resonance imaging
Authors: Stukalova O. V. , Shalaginova Yu. O. , Shakhnovich R. M. , Komarova A. G. , Lyakhova N. L. , Ternovoy S. K. , Staroverov I. I.
Published: August 2023

Introduction. The presence of diabetes mellitus in patients with acute infarction significantly worsens short- and long-term prognosis, but the features of the course of the infarction in this category of patients have not been fully studied.Objective. To compare clinical, functional and structural myocardial characteristics of patients with acute ST-segment elevation myocardial infarction with and without diabetes mellitus.Materials and methods. The study included 91 patients with revascularized ST-segment elevation myocardial infarction (41 patients with diabetes mellitus). All patients underwent cardiac MRI with contrast, including myocardial T1 mapping, tissue analysis of left ventricular myocardium with determination of infarct zone, heterogeneous zone, edema zone, pre- and post-contrast T1 values, extracellular volume values of healthy myocardium and infarct zone.Results. The presence of diabetes in patients with AMI was associated with increased EDV LV: 153 ± 38 and 181 ± 58 ml (p = 0.007), increased ESV LV: 76 ml [54–93] and 87 ml [71–122] (p = 0.035). Infarct size was significantly larger in patients with diabetes than in those without diabetes: 37 ± 15 g (95% CI: 33–41) and 47 ± 21 g (95% CI: 40–53), p = 0.017. Patients with acute infarction and diabetes mellitus had higher extracellular volume values in both healthy myocardium: 24% [22–27] and 28% [24–30], p = 0.002, and in the infarct zone: 48% [40–58] and 58% [50–61], p = 0.016.Conclusions. In patients with ST-segment elevation myocardial infarction with diabetes mellitus, the infarct size, the edema area, and the value of the extracellular volume fraction both in the infarct area and in the preserved myocardium were larger than in patients without diabetes, which may underlie the development of myocardial dysfunction and further progression of heart failure.
The role of acetylsalicylic acid in the treatment of diseases caused by atherosclerosis
Authors: Yavelov I. S.
Published: August 2023

Arterial involvement in atherosclerosis is systemic in nature and is not limited to a single vessel causing ischemic symptoms. Atherosclerotic plaques at various stages of development are simultaneously present in arteries of a patient with atherosclerosis, and many of them undergo cycles of rupture and repair without any clinical manifestations. The chronic use of antithrombotic drugs is one of the ways to prevent the development of clinically significant thrombosis after atherosclerotic plaque destabilization. For this purpose antiplatelet agents, are used in patients with diseases caused by atherosclerosis, who do not have indications for long-term use of high (therapeutic) doses of anticoagulants. At present, acetylsalicylic acid maintains a leading position of the main antithrombotic drug in monotherapy and a must component of composite antithrombotic therapy. Recent studies have limited its role only in certain clinical settings: (1) a prolonged (more than 1 month) use after coronary stenting in patients requiring a long-term use of high (therapeutic) doses of oral anticoagulants; (2) a long-term use after coronary stenting in some patients receiving acetylsalicylic acid combined with ticagrelor; (3) use as first-line drug monotherapy in patients with symptomatic atherosclerosis of arteries of the lower extremities; (4) a long-term use as first-line drug monotherapy after ischemic non-cardioembolic stroke. The use of acetylsalicylic acid requires adequate patient adherence to treatment and sufficient bioavailability of the active substance. When there are doubts on proper bioavailability, it is reasonable to use nonenteric-coated dosage forms of acetylsalicylic acid.
The efficacy and safety of apixaban: what has changed in 12 years of its use in real clinical practice?
Authors: Panchenko E. Р.
Published: August 2023

This review examines the position of apixaban among other direct oral anticoagulants in patients with atrial fibrillation (AF) and venous thrombosis in randomized clinical trials and real clinical practice. Since the advent of apixaban, many studies of real clinical practice (RCP) and meta-analyses have appeared. RCP studies have fully confirmed the efficacy and safety of apixaban. Now we have data that au pixaban is equally effective and safe in elderly and senile people and younger patients, as well as in patients with reduced creatinine clearance. The efficacy and safety of apixaban has been confirmed in patients with AF with the presence of diseases of several vascular basins, in patients with AF and angina, including acute coronary syndrome, treated by coronary artery stenting and conservatively. An important property of apixaban is safety, which can be traced in almost all studies, which made it possible to successfully apply it in people with a high risk of bleeding, namely in patients with active cancer and venous thrombosis. Thus, RCP studies in patients with AF, including the elderly and senile patients with chronic kidney disease, many concomitant diseases, as well as patients with VTEC, confirmed the results of randomized clinical trials of apixaban. The drug appears to be an effective and at the same time the safest anticoagulant. The safety image of Apixaban which has become noticeable in all RCTs (in patients with atrial fibrillation, VTEC, including patients with active cancer) was confirmed both in real clinical practice studies and meta-analyses, and allowed it to be successfully used in the category of patients which are at highest risk for bleeding.