bluuebunny/crossref_metadata_2025 huggingface dataset:
Uncomplicated epidural removal in a patient on a therapeutic heparin infusion: a case report
Authors: Hu Lizbeth , Adegboye Janet , Chang Angela Tung , Hanna Marie , Jaremko Kellie
Published: May 2024

Background

Unanticipated postoperative thrombotic complications can occur in complex patients who receive preoperative epidurals. Therefore, it is imperative that we consider the risks and benefits of epidural management in the setting of therapeutic anticoagulation. We present a case of epidural catheter removal on a heparin infusion, due to the extreme risk of holding anticoagulation for any duration.

Case report

A woman with hilar cholangiocarcinoma presented after uncomplicated hepatectomy, bile duct resection and hepaticojejunostomy, with a thoracic epidural for analgesia. On postoperative day 1, she developed a total portal vein thrombosis, requiring emergent open thrombectomy, transhepatic stenting and high-dose heparin infusion while the epidural was indwelling. The patient was deemed to have a profound risk of re-thrombosis if heparin were paused. Therefore, a multidisciplinary discussion between hepatobiliary surgery, critical care, neurosurgery, haematology, acute pain service and the patient’s family ensued regarding epidural management. Options included catheter-directed thrombolytics to her stent while holding systemic anticoagulation, sterilely leaving the epidural catheter in place indefinitely, injecting prothrombotic agent into the epidural prior to removal, or removing the catheter without holding anticoagulation. Due to the risk of re-thrombosis in the portal vein and liver infarction, the heparin infusion was decreased to achieve the lowest therapeutic anti-Xa level, and the epidural was removed. The patient was continuously monitored in the intensive care unit without any adverse events.

Conclusion

A multidisciplinary discussion is paramount to weigh the risk of epidural haematoma if a catheter is removed on therapeutic anticoagulation against catastrophic thrombosis if anticoagulation is paused.
Exploring the molecular interactions of dorzolamide hydrochloride in aqueous solutions: a comprehensive study using thermophysical techniques and molecular simulations across various temperatures
Authors: Rayinuthala Yesupadamu , Medepalli David Raju , Munnangi Srinivasa Reddy , Nayeem Sk Md , Ravulapalli Lakshmi Tulasi
Published: May 2024

This research begins with the initial assessment of key physical properties—density ( ρ), speed of sound ( u), and refractive index ( nD ) in binary aqueous solutions of dorzolamide hydrochloride. These properties were measured in solutions with varying molalities, ranging from 0.0 to 0.0276, under standard atmospheric conditions and at temperatures between 300.15 and 320.15 K. From these measurements, we were able to calculate a range of important parameters, including the apparent molar volume ( Vϕ), its limiting values ([Formula: see text]), limiting apparent molar expansivity ([Formula: see text]), Helper’s constant ([Formula: see text]), apparent molar isentropic compression ( κϕ), and its limiting values ([Formula: see text]), specific refraction ( RD), molar refraction ( RM), and hydration number ( nh). These calculated values provided insights into the strong interactions between the solute and solvent in the liquid system. They also shed light on the presence of various molecular interactions, such as inter- and intramolecular hydrogen bonds, dipole–dipole, and dipole-induced-dipole interactions, as well as the ability of the solute to influence the structure of the surrounding water molecules. Additionally, we derived the densities of dorzolamide hydrochloride solutions from molecular dynamics (MD) simulations, which showed a strong correlation with our experimental findings, underscoring the reliability of MD simulations in such studies. In the end, our combined study on dorzolamide hydrochloride in water demonstrates that it shapes structures because it has lower volumetric properties and stronger hydrogen bonds in MD simulations. More alchemical free energy calculations show that there are big changes in solvation energies. This is important for understanding how dorzolamide hydrochloride works in water.
Long-Term Mine Planning: A Survey of Classical, Hybrid and Artificial Intelligence-Based Methods
Authors: Binte Azhar Nurul Asyikeen , Gunawan Aldy , Cheng Shih-Fen , Leonardi Erwin
Published: May 2024

The aim of long-term mine planning (LTMP) is two-fold: to maximize the net present value of profits (NPV) and determine how ores are sequentially processed over the lifetime. This scheduling task is computationally complex as it is rife with variables, constraints, periods, uncertainties, and unique operations. In this paper, we present trends in the literature in the recent decade. One trend is the shift from deterministic toward stochastic problems as they reflect real-world complexities. A complexity of growing concern is also in sustainable mine planning. Another trend is the shift from traditional operational research solutions — relying on exact or (meta) heuristic methods — toward hybrid methods. They are compared through the scope of the problem formulation and discussed via solution quality, efficiency, and gaps. We finally conclude with opportunities to incorporate artificial intelligence (AI)-based methods due to paucity, multiple operational uncertainties simultaneously, sustainability indicator quantification, and benchmark instances.
Gauss–Bonnet source of Brans–Dicke scalar field and accelerated expansion of universe
Authors: Çiftci Dilek Kazıcı
Published: May 2024

In this work, using a different theoretical approach, we study a homogeneous and isotropic cosmological spacetime filled with a perfect fluid. Using the framework of Brans–Dicke (BD) and Gauss–Bonnet (GB) theories and including a scalar potential, we obtain the analytical solution of the field equations and find the field functions and the relevant expansion parameter of the spacetime. We assume that the BD and GB media can interact with each other, and hence that there is an energy transfer between these two components. Using this approach, we assume that the BD scalar field is related to intrinsic properties of the GB medium. We introduced a power-law scalar field [Formula: see text] and found the appropriate dynamical functions for the different powers p. We found that the expansion rate of spacetime also behaves as a power-law, and the accelerating expansion is always satisfied for this model. We also analyze the stability for physically acceptable critical points for a given scale factor.
Design of NiO–ZnCo2O4 heterostructures for room temperature H2S sensing
Authors: Akhtar Ali , Zhou Rujun , Chen Daru , Sadaf Shama , Fu Ce , Liu Jianqiao
Published: May 2024

Hydrogen sulfide (H2S) detection with novel sensing properties such as higher response and minimum detection limit at room temperature is essential to ensure the safety of humans and the environment. A hydrothermal method was utilized to synthesize NiO–ZnCo2O4 heterostructures. The purpose of these materials was to fabricate gas sensors and detect different hazardous gases. The intrinsic properties of synthesized products were studied to check the microstructure and morphological properties of the heterostructures. Different gas sensors performed gas sensing properties, and the significant properties such as high response (ratio of response in gas and response in air [Formula: see text]) towards 20[Formula: see text]ppm H2S, short response/recovery time (32/20 s), a low detection limit (0.5 ppm), and great selectivity were detected based on the gas sensor of NZCO-5 (5% NiO–ZnCo2O4) compared with other sensors NiO, NZCO-0 (0% NiO–ZnCo2O4) and NZCO-10 (10% NiO–ZnCo2O4). The significant H2S gas sensing improvement in this study could be a potential route for saving human lives.
How Does the Fractional Derivative Change the Complexity of the Caputo Standard Fractional Map
Authors: Orinaite Ugne , Telksniene Inga , Telksnys Tadas , Ragulskis Minvydas
Published: May 2024

The impact of power-law memory on the dynamics of the Caputo standard fractional map is investigated in this paper. The definition of a complexity measure for the Caputo standard fractional map is introduced. This measure evaluates both the average algebraic complexity of a trajectory and the distribution of the trajectories of different types in the phase space of the system. The interplay between the small-scale spatial chaos and the large-scale spatial behavior is observed and measured during the transition of the Caputo standard fractional map from the circle map to the classical standard map. It is demonstrated that the impact of the fractional derivative on the complexity of the fractional system is not straightforward and is predetermined by the physical properties governing the dynamics of that system.
DISSIPATION AND DISPERSION IN FRACTIONAL NONLINEAR WAVE DYNAMICS: ANALYTICAL AND NUMERICAL EXPLORATIONS
Authors: KHATER MOSTAFA M. A. , ALFALQI SULEMAN H.
Published: May 2024

The fractional nonlinear generalized [Formula: see text]-dimensional Chaffee–Infante (FGCI) equation is a nonlinear evolution equation that governs the propagation of waves in dispersive media, exhibiting both dissipative and dispersive effects. It finds applications in various fields such as fluid mechanics, plasma physics, and nonlinear optics, where the interplay between nonlinearity, dispersion, and dissipation plays a crucial role in determining the dynamics of the system. This study aims to obtain analytical and numerical solutions for the FGCI equation, which is a generalization of the Chaffee–Infante equation. The analytical approach employed is the Khater II (Khat II) method, an efficient technique for constructing approximate analytical solutions to nonlinear fractional differential equations. Additionally, He’s variational iteration (HVI) method is implemented as a numerical scheme to validate the accuracy of the analytical solutions obtained from the Khat II method. The results obtained through these methods demonstrate the effectiveness of the proposed techniques in solving the FGCI equation and provide valuable insights into the dynamics of wave propagation phenomena governed by the equation. The significance of this study lies in its contribution to the understanding of nonlinear wave propagation phenomena and the development of analytical and numerical techniques for solving fractional differential equations. The novelty of the research lies in the application of the Khat II method to the FGCI equation, which has not been previously explored, and the validation of the analytical solutions through the HVI method. The study is conducted in the field of applied mathematics, with a focus on nonlinear fractional differential equations and their applications in various physical systems.
Hybrid Long Short-Term Memory Fused Convolution Neural Network for Weather Forecasting
Authors: Myilvahanan J. Karthick , Sundaram N. Mohana , Santhosh R.
Published: May 2024

Weather forecasting is an effort by meteorologists to predict whether states at a few prospective times and the conditions of weather that might be estimated. With new modern technology, present weather forecasting methods are highly precise. To achieve high accuracy, the methods developed for weather forecasting were much more complicated owing to many factors. Here, the usage of time series data for weather forecasting is done by the devised Long-Short Term Memory fused Convolutional neural network (LSTMFCNN). At first, the acquisition of input time series data from the specific dataset is done. In The feature extraction technical features are done by considering the input time series data. Then, the feature extraction is done utilizing the Rider Optimization Algorithm-Based Neural Network (RideNN) with the Soergel metric. RideNN is the integration of the Rider Optimization Algorithm (ROA) with the Neural Network (NN) classifier. Thus, the feature fusion step reduces the complexity and improves the accuracy. Thereafter, the oversampling technique is utilized for the data augmentation (DA) process. Finally, weather forecasting is done utilizing the newly designed LSTMFCNN and is obtained by the integration of Convolutional Neural Network (CNN) and Deep Long-Short Term Memory (DLSTM).
Nano Zinc Oxide Particle Synthesis from Bio-Waste Selaginella willdenowii Leaf Extract: A Multi-Faceted Approach for Environmental and Biomedical Applications
Authors: Sudheesh Arjun K. , Alwin George C. , Joseph Kadanthottu Sebastian , Jaison Juhi Puthukulangara , Jose Joel
Published: May 2024

Selaginella willdenowii, a commonly used greenhouse fern, was often used as a biowaste to synthesize zinc oxide nanoparticles (ZnO NPs) in an eco-friendly and cost-effective way. UV–Visible spectra studies were carried out to confirm the synthesis of S. willdenowii-mediated ZnO NPs (SW-ZnO NPs), and a peak at 367[Formula: see text]nm with a sharp band gap of 3.415[Formula: see text]eV was observed. The X-ray diffraction analysis indicated that the crystalline size of the synthesized SW-ZnO NPs was 11.971[Formula: see text]nm. The phytochemicals present in the extracts and the compounds involved in the reduction of metal to nanoparticles were determined by Fourier Transform Infrared analysis. Scanning electron microscopy was utilized to analyze the surface morphology and size of the obtained SW-ZnO NPs. The examination revealed that they exhibited a hexagonal shape, with an average size falling within the range of 17–23[Formula: see text]nm. Under ultra-violet light, reactive blue 220 and reactive yellow 145 dyes showed 78.06% and 60.14% degradation, showing potential photocatalytic degradation activity. The synthesized SW-ZnO NPs also exhibited antimicrobial activity against bacterial strains (Escherichia coli and Bacillus subtilis) and fungal cultures (Candida tropicalis and Candida albicans) showed cytotoxic activity against Hep-G2 cell lines. Our results suggest the green synthesized SW-ZnO NPs have potential photocatalytic, antimicrobial and cytotoxic potential.
Does Age Matter for Innovative Behavior? A Mediated Moderation Model of Organizational Justice, Creative Self-Efficacy, and Innovative Behavior Among IT Professionals
Authors: Qammar Ahmad , Aslam Muhammad Shakeel , Khan Sadeeqa Riaz , Jabeen Nasira , Amentie Melkamu Deressa
Published: May 2024

The significance of innovation and the expectation for employees to exhibit innovative behavior have been heightened as a result of swift technological advancements and an evolving business landscape. The present research is aimed at examining the impact of organizational justice on fostering innovation in a dynamic business environment. Extending the previous literature which generally examined the combined impact of different facets of organizational justice, we employed the social cognitive theory framework to investigate the mechanism through which the three facets of organizational justice (distributive justice, procedural justice, and interactional justice) lead to employee innovative behavior through the mediating role of employees’ creative self-efficacy. Additionally, we examined the role of age as a pertinent boundary condition, an aspect often overlooked in the literature on creative self-efficacy and innovative behavior which is likely to augment our understanding of the potential mechanism driving innovative behavior. The sample comprises 320 individuals employed in the information technology industry. The data were collected in two waves, and subsequent analysis was conducted utilizing the Warp PLS 8 software. The present investigation employed partial least square (PLS)-based structural equation modeling (SEM) to conduct analysis and evaluate hypotheses. The results indicate that all three facets of organizational justice have a positive influence on employees’ creative self-efficacy, which subsequently manifests in their innovative behavior. Additionally, age has an impact on the relationship between creative self-efficacy and employee innovative behavior, which becomes less pronounced as employees get older. Theoretical contributions and practical implications for practitioners are discussed.
BRAF Expression and Copy Number Alterations Predict Unfavorable Tumor Features and Adverse Outcomes in Patients With Breast Cancer
Authors: Alhamdan Yazan R. , Ayoub Nehad M. , Jaradat Sara K. , Shatnawi Aymen , Yaghan Rami J.
Published: May 2024

Background: The role of BRAF in breast cancer pathogenesis is still unclear. To address this knowledge gap, this study is aimed at evaluating the impact of BRAF gene expression and copy number alterations (CNAs) on clinicopathologic characteristics and survival in patients with breast cancer.Methods: The Molecular Taxonomy of Breast Cancer International Consortium (METABRIC) dataset was obtained from the cBioPortal public domain. Tumoral BRAF mRNA expression and CNAs along with demographic and tumor data for patients with breast cancer were retrieved. The association of BRAF expression and CNAs with breast cancer clinicopathologic characteristics was analyzed. The impact of BRAF mRNA expression on the overall survival of patients was assessed using Kaplan–Meier survival analysis.Results: BRAF gene mRNA log intensity expression was positively correlated with tumor size and the Nottingham Prognostic Index (NPI) (p<0.001). Alternatively, BRAF gene expression was negatively correlated with the age at diagnosis (p=0.003). The average BRAF mRNA expression was significantly higher in premenopausal patients, patients with high tumor grade, hormone receptor–negative status, and non-luminal tumors compared to postmenopausal patients, patients with low-grade, hormone receptor–positive, and luminal disease. BRAF gain and high-level amplification copy numbers were significantly associated with higher NPI scores and larger tumor sizes compared to neutral copy number status. Survival analysis revealed no discernible differences in overall survival for patients with low and high BRAF mRNA expression.Conclusion: High BRAF mRNA expression as well as the gain and high-level amplification copy numbers were associated with advanced tumor characteristics and unfavorable prognostic factors in breast cancer. BRAF could be an appealing target for the treatment of premenopausal patients with hormone receptor–negative breast cancer.
Factors Contributing to Nurses’ Intention to Leave the Profession: A Qualitative Study in Catalonia, Spain, following the Latest Waves of COVID-19
Authors: Watson Carolina E. , Bernabeu-Tamayo Maria Dolors , Giménez-Díez David , Lillo-Crespo Manuel , Leyva-Moral Juan M.
Published: May 2024

Introduction. The COVID-19 pandemic has had a significant impact on healthcare professionals globally, with nurses facing diverse challenges at the forefront. Despite their resilience, nurses are experiencing emotional burdens, which have contributed to a growing intention to abandon the profession. Understanding these factors is crucial for addressing the global nursing shortage. Methods. A qualitative descriptive approach was utilized for this study. Nurses who were actively working during the last waves of the pandemic in Catalonia, Spain, were intentionally recruited through social media and personal contacts, and data were collected through online semistructured interviews until data saturation was reached. Data were analyzed using Braun and Clarke’s thematic analysis method. Results. Fourteen nurses, with an average of 22.8 years of work experience, were interviewed. Thematic analysis revealed three main themes: (1) the impact of COVID-19 on health, (2) factors influencing the decision to stay, and (3) recommendations to improve crisis management. Conclusion. Nurses faced significant emotional impacts but demonstrated dedication and resilience. Their decision to persevere was influenced by factors such as responsibility, guilt, and economic stability. Urgent measures are necessary to provide tailored mental health support and recognize emotional challenges in crisis preparedness.
Early Warning Simulation of Urban Vulnerability in Coal‐Resource‐Based Cities Based on System Dynamics
Authors: Feng Dongmei , Wang Liang , Duan Xiumei
Published: May 2024

Coal‐resource‐based cities, as one of the important types of typical resource‐based cities in China, have strong characteristics of instability, sensitivity, and fragility, exhibiting a series of vulnerability features of the human‐land system. Previous studies have lacked a deeper investigation into the vulnerability of such cities from the perspective of coupling feedback mechanisms among various elements or subsystems. This paper adopts Bohle et al.’s “Dual Structure Model” of vulnerability to establish an indicator system for vulnerability warning in coal‐resource‐based cities. Using Fushun City as a sample, a dynamic simulation model of vulnerability in coal‐resource‐based cities is constructed based on system dynamics for warning simulation calculations, analyzing the evolution trend of vulnerability in Fushun City from 2010 to 2022. The results show the following: (1) from 2010 to 2022, the urban vulnerability of Fushun City transitioned from a medium warning level to a relatively safe level, showing a trend of annual reduction and improvement, undergoing three development stages of significant reduction, fluctuation stabilization, and slight rebound. (2) Due to the causal relationships among various elements within the vulnerability subsystems of Fushun City, differences exist in the contribution levels of vulnerability subsystems during the period 2010–2022, under the combined effects of sensitivity and adaptability factors. The contribution rate of the natural subsystem was the highest from 2010 to 2014, while, from 2016 to 2019, urban vulnerability began to shift towards an economically and socially dominant type. Influenced by the pandemic, Fushun City’s overall vulnerability has shown an upward trend since 2020 compared to the previous stage. Finally, specific policy suggestions are proposed for Fushun City to cope with vulnerability changes based on the analysis results, providing a theoretical basis for achieving sustainable development in such coal‐resource‐based cities.
Supplementary Table 4 from LYVE-1–expressing Macrophages Modulate the Hyaluronan-containing Extracellular Matrix in the Mammary Stroma and Contribute to Mammary Tumor Growth
Authors: Elfstrum Alexis K. , Rumahorbo Annisa H. , Reese Lyndsay E. , Nelson Emma V. , McCluskey Braedan M. , Schwertfeger Kathryn L.
Published: May 2024

Table depicting total cell counts for each scRNA-seq cluster in both Lyve1CreCsfrfl/fl and Csfrfl/fl mice.
Supplementary Figure 2 from LYVE-1–expressing Macrophages Modulate the Hyaluronan-containing Extracellular Matrix in the Mammary Stroma and Contribute to Mammary Tumor Growth
Authors: Elfstrum Alexis K. , Rumahorbo Annisa H. , Reese Lyndsay E. , Nelson Emma V. , McCluskey Braedan M. , Schwertfeger Kathryn L.
Published: May 2024

Figure S2 depicts representative mammary gland flow cytometry gating
FIGURE 5 from LYVE-1–expressing Macrophages Modulate the Hyaluronan-containing Extracellular Matrix in the Mammary Stroma and Contribute to Mammary Tumor Growth
Authors: Elfstrum Alexis K. , Rumahorbo Annisa H. , Reese Lyndsay E. , Nelson Emma V. , McCluskey Braedan M. , Schwertfeger Kathryn L.
Published: May 2024

scRNA-seq identifies macrophage subsets in the tumor microenvironment. A, UMAP projection of 17 distinct clusters from the total population of CD45+ cells from EO771 tumors from Csf1rfl/fl and Lyve1CreCsf1rfl/fl mice (n = 2 per genotype) with cell-specific labels. B, Dot plot of macrophage-associated genes from cells derived from Csf1rfl/fl tumors. C, Dot plot of enriched genes in macrophage clusters. D, Intercluster GSEA from Csf1rfl/fl macrophage clusters [normalized enrichment scale (NES) adjusted P-value < 0.05] with detailed gene set names in Supplementary Table S2. E, Feature plot of Folr2 from tumors from Csf1rfl/fl and Lyve1CreCsf1rfl/fl mice. F, Average cell counts per cluster from tumors from Csf1rfl/fl and Lyve1CreCsf1rfl/fl mice. G, Waterfall plots of relative enrichment in cluster 7 Lyve1CreCsf1rfl/fl relative to Csf1rfl/fl of genes associated with glycosaminoglycan binding.
FIGURE 4 from LYVE-1–expressing Macrophages Modulate the Hyaluronan-containing Extracellular Matrix in the Mammary Stroma and Contribute to Mammary Tumor Growth
Authors: Elfstrum Alexis K. , Rumahorbo Annisa H. , Reese Lyndsay E. , Nelson Emma V. , McCluskey Braedan M. , Schwertfeger Kathryn L.
Published: May 2024

LYVE-1 expression correlates with HA internalization. J774 macrophages untreated or treated with MCSF, IL4, dexamethasone, and EO771 conditioned media assessed for LYVE-1 expression (A) and CD44 expression (B) by flow cytometry. J774 macrophages untreated or treated with MCSF, IL4, dexamethasone, and EO771 conditioned media and pretreated with an isotype control or LYVE-1 blocking antibody followed by incubation with LMW-HA (C) or HMW-HA (D) and assessed by flow cytometry. Untreated and treated J774 macrophages assayed for hyaluronidase protein by ELISA (E) and hyaluronidase activity assay (F). G, Tumor lysates from Csf1rfl/fl and LyveCre Csf1rfl/fl mice assayed by HA Activity ELISA (n = 5). H, EO771 tumors from Csf1rfl/fl (gray) and LyveCre Csf1rfl/fl (blue) mice assessed for HA by ELISA and normalized by weight. J774 macrophages untreated or treated and incubated with LMW-HA (I) or HMW-HA (J) and assessed for HA internalization by flow cytometry. *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001. Each dot represents one replicate.
Reabilitação baseada na comunidade - discutindo estratégias de ação no contexto sociocultural
Authors: Oliver Fátima Corrêa , Almeida Marta Carvalho de , Tissi Maria Cristina , Castro Luciana Hernandez , Formagio Simone
Published: May 2024

This paper aims to introduce the Community-Based Rehabilitation (CBR) as an interconnected theme to the development ofmultisector actions (health, education, work and social action) carried out with the community participation. To make easy the access for disabled people to the rehabilitation services, the International Health and Rehabilitation Organizations suggested a (CBR), as one of their enlargement strategies of aid coverage ffom local resources management mainly to the Third World. In the light of this proposition, purposes are discussed for the implantation ofrehabilitation actions with community participation from an experience in progress in São Paulo city-Brazil. In this case there is an emphasis on territorial labor with the local people's mobilization, including the disabled. By changing the "place" of the rehabilitation actions the professionals will face another subject, now integrated into the sociocultural context. The professionals reviewing and establishing new means/looks to decode the pertaining leveis of the disabled, form a differentiated view of the subject. They transfer part of their knowledge of the fíeld simplifying it, making it public and democratized. The experience in progress counts on the occupational therapists participation (professionals and graduate students) from social organizatiofrs representatives (school, day care center and health unit) from pastoral sections connected with the Roman Catholic Church, the local Child and Juvenile Protective Council, from relativos and the disabled, as well as volunteers. The project is being developed by a management group and plenary meeting for planing and assessment. Disabled people are followed up and general population in income generation activities for adults, group familiarity and sociocultural activities and local discussion of the disabled people^ needs and the general population in a particular sociocultural context. That would be a way to know the sociocultural context to locate subjects and knowledge about that group and their problems. Far more complex than increase the aid coverage or create services and rehabilitation actions at a low cost, it is to contribute to the production of the emancipation process and the self-management for the disabled.
Trabalho e inclusão social: depoimentos de pessoas com deficiências
Authors: Tissi Maria Cristina
Published: May 2024

Trata-se de abordar a temática deficiência e trabalho partindo do eixo inclusão/ exclusão social. Os dados foram coletados a partir de entrevistas semi-estruturadas - depoimentos - de pessoas com deficiências físicas que atuam no comércio ambulante na cidade de São Paulo e da observação direta do trabalho. Foram analisadas as dimensões concretas e simbólicas atribuídas ao trabalho segundo os eixos da sociabilidade e da integração no trabalho usados por Robert Castel na abordagem de situações de precariedade. Os resultados mostram que, do ponto de vista do processo de trabalho, a atuação no comércio ambulante revela traços de degradação moral e política; opõe-se à cidadania, à liberdade de expressão de idéias e interesses, à manutenção e à garantia de direitos. Contraditoriamente, o comércio ambulante proporciona interações sociais com diversos agentes, expressando conflitos, mas também solidariedade e amizade. É também modalidade de integração econômica, ocorrendo nos interstícios da produção capitalista, de forma que os ambulantes inserem-se numa extensa trama de relações de trocas sociais. Inclusão e exclusão social não são pólos antagônicos. O que se coloca em questão são os elementos que concorrem na qualidade da inclusão realizada sob a exclusão social. Os indicadores encontrados revelam que a inclusão realizada é precária, precariedade menos da ordem material do que política e moral. Os entrevistados não podem ser considerados excluídos, tampouco constituem a zona de desfiliação, aproximando-se melhor da zona de vulnerabilidade caracterizada por Robert Castel.
Late Summer Lake Nojiri
Authors: Harmon Maurice
Published: May 2024

“Late Summer Lake Nojiri,” by Maurice Harmon.
Contemporary Irish Novels
Authors: Imhof Rüdiger
Published: May 2024

Edna O'Brien, Wild Decembers. London: Weidenfeld & Nicolson, 1999; 247pp., £ 16.99, ISBN 0-297-64576-5. Roddy Doyle, A Star Called Henry. London: Cape, 1999; 344pp.; € 16.99; ISBN 224-06019-8.
Impacto de uma pesquisa-ação nos indicadores vacinais em Minas Gerais
Authors: Souza Janaina Fonseca Almeida , Silva Thales Philipe Rodrigues da , Oliveira Thais Moreira , Vimieiro Aline Mendes , Teixeira Antônia Maria da Silva , Soares Adriana Coelho , Ribeiro Elice Eliane Nobre , Freitas Giselle Lima de , Gaspar Eduarda Dantas , Matozinhos Fernanda Penido
Published: May 2024

Esta errata corrige o artigo:  https://doi.org/10.11606/s1518-8787.2024058005484
Influence of the Manufacturing Trinomial (Technology, Printer, and Material) on the Marginal and Internal Discrepancies of Printed Metal Frameworks for the Fabrication of Tooth-Supported Prostheses: A Systematic Review and Meta-analysis
Authors: Revilla-León Marta , Gómez-Polo Miguel , Barmak Abdul B. , Yilmaz Burak , Rutkunas Vygandas , Kois John C.
Published: May 2024

Purpose: The purpose of this systematic review and meta-analysis was to compare the influence of fabrication method (conventional, subtractive, and additive procedures) and manufacturing trinomial (technology, printer, and material combination) on the marginal and internal fit of cobaltchromium (Co-Cr) tooth-supported frameworks. Materials and Methods: An electronic systematic review was performed in five data bases: MEDLINE/PubMed, Embase, World of Science, Cochrane, and Scopus. Studies that reported the marginal and internal discrepancies of tooth-supported Co-Cr additive manufacturing (AM) frameworks were included. Two authors independently completed the quality assessment of the studies by applying the Joanna Briggs Institute Critical appraisal Checklist for Quasi-Experimental Studies. A third examiner was consulted to resolve lack of consensus. Results: A total of 31 articles were included and classified based on the evaluation method: manufacturing accuracy, the dual- or triple-scan method, stereomicroscope, optical coordinate measurement machine, microCT, profilometer, and silicone replica. Six subgroups were created: 3D Systems, Bego, Concept Laser, EOS, Kulzer, and Sisma. Due to the heterogeneity and limited data available, only the silicone replica group was considered for meta-analysis. The meta-analysis showed a mean marginal discrepancy of 91.09 μm (I2 = 95%, P < .001) in the conventional group, 77.48 μm (I2 = 99%, P < .001) in the milling group, and 82.92 μm (I2 = 98%, P < .001) in the printing group. Additionally, a mean internal discrepancy of 111.29 μm (I2 = 94%, P < .001) was obtained in the conventional casting group, 121.96 μm (I2 = 100%, P < .001) in the milling group, and 121.25 μm (I2 = 99%, P < .001) in the printing group. Conclusions: Manufacturing method and selective laser melting (SLM) metal manufacturing trinomial did not impact the marginal and internal discrepancies of Co-Cr frameworks for the fabrication of tooth-supported restorations.
Coronary Artery Obstruction After Transcatheter Aortic Valve Implantation: Past, Present, and Future
Authors: Ibrahim Homam , Chaus Adib , Alkhalil Ahmed , Prescher Lindsey , Kleiman Neal
Published: May 2024

Coronary obstruction (CO) is a rare but critical complication of transcatheter aortic valve implantation. It is associated with significant morbidity and mortality. This comprehensive review elucidates the evolving landscape of CO risk assessment and management strategies in the contemporary era of transcatheter aortic valve implantation. Drawing upon recent advances in computed tomography angiography, we delve into the nuanced evaluation of anatomic parameters crucial for predicting CO risk. Furthermore, this review explores the utility of interventional and surgical techniques, including chimney stenting and leaflet modification systems, in mitigating CO complications. In summary, this review serves as a practical guide for clinicians navigating the complexities of CO prevention and management in the evolving landscape of transcatheter aortic valve implantation, with the goal of optimizing patient outcomes and ensuring procedural success.
Hypertension Prevalence and Related Risk Factors Among Mexican American Adults Are Increasing: National Health and Nutrition Examination Survey 1999 to 2018
Authors: Briggs Early Kathaleen , Valencia Sandra I. , Stendell‐Hollis Nicole , Klyve Dominic , Gee David L.
Published: May 2024

Background

Acculturation affects hypertension prevalence among Hispanic people, but there have been no recent analyses specifically focused on Mexican American (MA) people. We sought to determine age‐adjusted hypertension prevalence, abdominal obesity, and acculturation trends among MA adults and non‐Hispanic White adults.

Methods and Results

Data from the NHANES (National Health and Nutrition Examination Survey) were analyzed in 2‐year increments to observe trends in hypertension and risk factors (age, sex, body mass index, smoking status, abdominal obesity, waist‐to‐height ratio (WHtR), education, and income). Acculturation was based on three commonly used measures. The sample included 30 920 adults. Age‐adjusted hypertension prevalence is higher in MA adults (52.7%) than White adults (48.3%). Hypertension risk factors—age, obesity prevalence, WHtR, acculturation—all significantly increased among MA adults, while smoking declined. Higher acculturation scores increased hypertension likelihood (odds ratio [OR], 1.44 [95% CI, 0.91–1.97]) for MA adults compared with those with lower acculturation scores. White adults with elevated WHtR >0.5 had a 40% higher risk of hypertension than those with WHtR <0.5, but among MA adults, elevated WHtR did
not
increase risk for hypertension. There was a significant
increase
in hypertension prevalence among MA adults from 2003 to 2018 at an average biennial rate of 2.23%. There was no change in hypertension prevalence among White adults from 1999 to 2018.

Conclusions

Over 20 years of NHANES, more highly acculturated MA adults were at greater risk for hypertension, despite declines in smoking and controlling for age, sex, obesity status, education, and income. Finding ways to promote more traditional lifestyle and eating habits for MA adults could be a beneficial approach to reducing hypertension risk factors in this population.
Safety and Efficacy of the Bimodal Armadillo Catheter for Intracranial Interventions via the Transfemoral Approach
Authors: Katz Jeffrey M. , Khawar Haroon , Huang Brendan , Chulpayev Boris , Jung Richard
Published: May 2024

BACKGROUND

The Armadillo (Q'Apel Medical Inc., Fremont, CA) is a novel bimodal guide catheter, combining properties of a long support sheath with a large‐bore distal access catheter, whose stiffness can be adjusted from “track” mode during navigation to “support” mode for intervention. The main objective of this study was to determine the safety and efficacy of the Armadillo for intracranial interventions via the transfemoral approach.

METHODS

This is a retrospective study of our initial Armadillo experience, composed of all patients who underwent an intracranial intervention using the Armadillo via the transfemoral route, between December 2022 and December 2023, at a single institution. Transvenous, external carotid, and stroke‐related interventions were excluded.

RESULTS

Of 62 total interventions with the Armadillo catheter, 58 procedures (53/58 [91.4%] for aneurysms, 3/58 [5.6%] for arteriovenous malformations, and 2/58 [3.4%] for intracranial stenosis) in 55 patients (mean age, 57.2 [standrad deviation (SD), 12.4] years; 46/55 [83.6%] female sex) met study criteria. Most interventions were in the anterior circulation (51/58 [87.9%]) and significant carotid or vertebral artery tortuosity was encountered in 10 of 58 (17.2%) cases. The Armadillo was the primary sheath in 57/58 (98.3%) cases, and 50/58 (86.2%) received vasodilator for vasospasm prophylaxis prior to distal navigation. The Armadillo was successfully navigated to the intended target location in 52 of 58 (89.7%) procedures, predominantly over a macro‐guidewire alone (41/58 [70.7%]). The need for a triaxial system during the intervention was obviated in 36 of 58 (62.1%) procedures, and all interventions were completed successfully without having to exchange for an alternate support catheter. There were no Armadillo‐related complications.

CONCLUSION

The Armadillo was highly effective as a long guide sheath for intracranial interventions via the transfemoral route, with a high rate of successful distal navigation and no device‐related complications.
What Is a Visual Stream?
Authors: Ritchie J. Brendan , Montesinos Sebastian , Carter Maleah J.
Published: May 2024

The dual stream model of the human and non-human primate visual systems remains Leslie Ungerleider's (1946–2020) most indelible contribution to visual neuroscience. In this model, a dorsal “where” stream specialized for visuospatial representation extends through occipitoparietal cortex, whereas a ventral “what” stream specialized for representing object qualities extends through occipitotemporal cortex. Over time, this model underwent a number of revisions and expansions. In one of her last scientific contributions, Leslie proposed a third visual stream specialized for representing dynamic signals related to social perception. This alteration invites the question: What is a visual stream, and how are different visual streams individuated? In this article, we first consider and reject a simple answer to this question based on a common idealizing visualization of the model, which conflicts with the complexities of the visual system that the model was intended to capture. Next, we propose a taxonomic answer that takes inspiration from the philosophy of science and Leslie's body of work, which distinguishes between neural mechanisms, pathways, and streams. In this taxonomy, visual streams are superordinate to pathways and mechanisms and provide individuation conditions for determining whether collections of cortical connections delineate different visual streams. Given this characterization, we suggest that the proposed third visual stream does not yet meet these conditions, although the tripartite model still suggests important revisions to how we think about the organization of the human and non-human primate visual systems.
A Phenomenological Investigation of the Experiential Features of Trauma
Authors: Hovila Tiia-Mari
Published: May 2024

This article examines the experience of trauma, paying particular attention to how traumatization affects one’s sense of body, time, and intersubjectivity. Furthermore, this study provides one example of how literature can be used in phenomenological research. Using both classical and contemporary phenomenological sources and deepening the analysis by discussing a first-person description by Marguerite Duras, the article aims to clarify one crucial aspect of traumatic experience: trauma alters experiential features so that the relation between traumatic past and present becomes rigid.
Variations of Kelvin Waves around the Tropical Tropopause Inversion Layer from GNSS RO Measurements
Authors: Li Jiahua , Xu Xiaohua , Luo Jia
Published: May 2024

In the present study, the tropical tropopause inversion layer (TIL) Kelvin waves are extracted from the Global Navigation Satellite System (GNSS) radio occultation (RO) temperature data of multiple missions from January 2007 to December 2020. We focus on the variations of TIL Kelvin waves in two longitude regions, the Maritime Continent (MC; 90°–150°E) and the Pacific Ocean (PO; 170°–230°E). The results show that over both regions, ENSO leads to the opposite variations of TIL Kelvin wave temperature amplitude during different ENSO phases. Specifically, during La Niña, the strong (weak) deep convection over MC (PO) leads to strengthened (weakened) static stability. With enhanced easterly (westerly) winds and strengthened (weakened) static stability, the TIL Kelvin wave temperature amplitudes are stronger (weaker) over MC (PO). The opposite phenomenon occurs during El Niño. The zonal-mean zonal winds affect TIL Kelvin wave temperature amplitudes by two mechanisms. First, the prevalence of easterlies (westerlies) in the upper troposphere affects the upward propagation of Kelvin waves, resulting in stronger (weaker) TIL Kelvin wave temperature amplitudes over MC (PO). Second, the TIL Kelvin wave temperature amplitude peaks about 2 months before the zero-wind line of the descending westerly QBO phase occurs, due to dissipation on the critical line. Additionally, the rapid increase of zonal-mean static stability significantly affects the annual variation of TIL Kelvin wave temperature amplitudes. They both reach maxima during DJF and minima during JJA, which should be related to the annual cycles of temperature and ozone mixing ratio in the TIL.

Significance Statement

Recent studies indicate that the Kelvin wave temperature amplitudes in the tropical tropopause inversion layer (TIL) exhibit distinct characteristics compared with those in other height levels, while the modulation mechanisms of the TIL Kelvin waves need further investigation. The present study aims to study the differences in the variabilities and the modulation factors of TIL Kelvin waves over two longitude regions. Our findings suggest that the different responses of background conditions during ENSO phases influence the spatiotemporal distribution of the TIL Kelvin waves. Besides, the zonal winds and the static stability significantly affect the temporal variations of TIL Kelvin waves. Our work fills the research gap of TIL Kelvin waves and contributes to understanding the dynamics of tropical tropopause variations.
Does the Surgical Approach Affect the Incidence of Post-Hepatectomy Liver Failure in Cirrhotic Patients? An Analysis of the NSQIP Database
Authors: Jehan Faisal S. , Ganguli Sangrag , Hase Niklas E. , Seth Abhinav , Kwon Yong , Hemming Alan W. , Aziz Hassan
Published: May 2024

Background: The association between surgical approach and post-hepatectomy liver failure (PHLF) in cirrhotic patients is poorly understood. We hypothesize that patients will have similar rates of liver failure regardless of whether they undergo minimally invasive liver resection (MILR) or open liver resection (OLR) in major liver resections. In contrast, there will be lower rates of PHLF in patients undergoing minor hepatectomy via the MILR approach.

Methods: Propensity score matching was used to analyze regression by matching the MILR to the OLR cohort. Patient demographics from the American College of Surgeons National Surgical Quality Improvement Program, including race, age, gender, and ethnicity, were matched. Chronic obstructive pulmonary disease, congestive heart failure, smoking, hypertension, diabetes, renal failure, dyspnea, dialysis dependence, body mass index, and American Society of Anesthesiologists (ASA) classification (>ASA III) were among the preoperative patient characteristics subject to matching. PHLF (Grade A vs B. vs C) was our primary outcome measure.

Results: A total of 2129 cirrhotic patients were included in the study. In the minor hepatectomy group, patients undergoing an OLR were more likely to get discharged to a facility (7.0% vs 4.4%; P = .03), had greater hospital length of stay (5 vs 3 days; P = .02), and had a greater need for invasive postoperative interventions (10.7% vs 4.6%; P < .01). They were also noted to have higher rates of organ space superficial surgical infections (SSIs) (7.3% vs 3.7%; P = .003), Clostridium difficile infection (.9% vs .1%; P = .05), renal insufficiency (2.1% vs .1%; P < .01), unplanned intubations (3.1% vs 1.4%; P = .03), and Grade C liver failure (2.3% vs .9%; P = .03).

Conclusion: A higher incidence of PHLF grade C was found in patients undergoing OLR in the minor hepatectomy group. Therefore, in cirrhotic patients who can tolerate minimally invasive approaches, MILR should be offered to prevent postoperative complications as part of their optimization plan.
An Analysis on the Effect of Income Changes in the Resection of Early-Stage Pancreatic Adenocarcinoma
Authors: Irfan Ahmer , Rose J. Bart , Dudeja Vikas , Chu Daniel I. , Reddy Sushanth
Published: May 2024

Introduction

The impact of socioeconomic inequalities on cancer care and outcomes has been well recognized and the underlying causes are likely multifactorial. Income is regarded as a cornerstone of socioeconomic status and has been assumed to correlate with access to care. We therefore sought to investigate whether income and changes in income would affect the rate of patients undergoing surgical resection for early-stage pancreatic cancer.

Methods

Inflation-adjusted income data were obtained from the United States Census Bureau from 2010 to 2019. The cancer data were obtained from the SEER database. Counties present in both data sets were included in the analysis. Patients with stage I or II pancreatic cancer who underwent formal resection were deemed to have undergone appropriate surgical management. Patients were grouped into an early (2010-2014) and late (2015-2019) time period.

Results

The final analysis included 23968 patients from 173 counties across 11 states. The resection rate was 45.1% for the entire study and rose from 42.8% to 47.4% from the early to late time periods ( P < .001). The median change in income between the two time periods was an increase by $2387. The rate of resection was not dependent on income class or income change in our study population.

Conclusion

Our surgical care of pancreatic cancer is improving with more patients undergoing resection. In addition, there are now fewer disparities between patients of lower-income and higher-income groups with respect to receiving surgical intervention. This implies that our access to care has improved over the past decade. This is an encouraging finding with regards to reducing health care disparities.