bluuebunny/crossref_metadata_2025 huggingface dataset:
Nascer nas Casas de Parto do Brasil: protocolo de pesquisa
Authors: Leister Nathalie , Bussadori Jamile Claro de Castro , Esteves-Pereira Ana Paula , Gama Silvana Granado Nogueira da , Lopes Gisele Almeida , Riesco Maria Luiza Gonzalez , Santos Nágela Cristine Pinheiro , Alonso Bruna Dias , Cintra Nayara Ruiz , Leal Maria do Carmo , McCourt Christine
Published: February 2025

Os Centros de Parto Normal (CPN) no Brasil são definidos como unidades de saúde vinculadas a um estabelecimento hospitalar, podendo estar localizados em suas dependências internas (CPN intra-hospitalares) ou imediações (CPN peri-hospitalares ou Casa de Parto). As estruturas física e assistencial das Casas de Parto são definidas pelo Ministério da Saúde. Fazem parte do seu modelo de cuidado as práticas adequadas, bons desfechos maternos e infantis e a promoção da experiência positiva da mulher no parto. O Nascer nas Casas de Parto do Brasil é um estudo transversal, em âmbito nacional, com os objetivos principais de avaliar a estrutura das Casas de Parto para atendimento a partos de risco habitual; avaliar a assistência ao parto e nascimento nas Casas de Parto; comparar os resultados desta pesquisa com os de nascimentos de risco habitual ocorridos nos hospitais amostrados na pesquisa Nascer no Brasil II. Este artigo tem como objetivo informar o delineamento e as etapas metodológicas propostas para o Nascer nas Casas de Parto do Brasil. Foram selecionadas oito Casas de Parto e fazem parte da amostra as gestoras dos serviços e 1.560 mulheres usuárias. A coleta de dados compreende o período de agosto de 2022 a outubro de 2024. Apresentam-se as variáveis do estudo e instrumentos, as etapas de coleta de dados desde a admissão até 120 dias após o parto, as atividades da equipe de pesquisa, o plano de análise dos dados e os aspectos éticos. Discute-se a relevância da divulgação deste protocolo de pesquisa e as especificidades de pesquisa em Casas de Parto.
Predictions of past and future climate distribution of the Orthosia songi Chen et Zhang (Lepidoptera: Noctuidae) based on the MaxEnt model in China
Authors: Wu Sijun , Qiao Tianmin , Li Shujiang , Hu Binhong , Zhu Tianhui
Published: February 2025

ABSTRACT: The Orthosia songi Chen et Zhang is one of the important leaf-eating pests of eucommia. In this paper, combined global climatic data with the distribution points of Orthosia songi and identified the key environmental factors affecting its distribution by knife cutting, PCA principal component analysis and Spearman correlation analysis. Used MaxEnt to fit the potential distribution areas in the past and future, and marked the offset mass points to analyse the migration trend of Orthosia songi distribution. The results showed that in 1970-2000, the 10 key variables were Tmin01, Prec02 ,Bio03, Bio04, Tmax01, Slope, Aspect , Tmax04, Bio02 and Tmax06 ; in 2021-2100, the factors were Bio02, Tmin10, Bio04, Tmax06,Prec09, Bio03,Prec03, Tmax03, Slope and Tmax10. Potential suitable areas for Orthosia songi in China were divided into 4 classes, with the unsuitable areas having the highest proportion (78.76%) and the high-suitable areas were lowest (5.45%). The fitness zone mass point of Orthosia songi was in Hubei Province in 1970-2000, and then shifted overall to the southeast, and shifted to Hunan Province in 2021-2100.
Ondas de Bloch em um metamaterial acústico periódico dispersivo
Authors: Almeida G. do N. , Vergara E. F. , Lenzi A.
Published: February 2025

A propagação de ondas mecânicas e eletromagnéticas em estruturas com periodicidade espacial tornou-seum campo relevante, especialmente quando os aspectos científico, tecnológico e de inovação são considerados. Embora o comportamento dos fenômenos físicos associado a estruturas periódicas tenham se consolidado ao longo dos últimos anos, o caso acústico ainda é um campo de estudo pouco explorado e neste sentido se faz necessário. Neste trabalho, investigamos alguns fenômenos subjacente ao comportamento das ondas de Bloch em um metamaterial acústico periódico dispersivo. O formalismo matemático da matriz detransferência considerando as perdas visco-térmicas combinada ao teorema de Bloch-Floquet unidimensional são adotados e se revelam suficientemente precisos para descrever e extrair as características da estrutura periódica. Conceitos como dispersão sonora, velocidade de fase e bandas de frequências proibidas (bandgaps) são abordados, e seus respectivos comportamentos são apoiados por resultados experimentais. Além disso, uma estratégia de como estabelecer a localização e a dimensão destes bandgaps é apresentada. Por fim, este estudo possibilita uma discussão no campo da física ondulatória, particularmente sobre o comportamento das ondas sonoras dissipativas que se propagam em estruturas periódicas.
Comparison of calibration methods in the analysis of 2013 Brazilian National Health Survey data
Authors: Souza Juliana Sena de , Barbian Márcia Helena , Reis Rodrigo Citton Padilha dos
Published: February 2025

ABSTRACT Objective: This study aims to compare calibration methods for weights in the subsample of Laboratory Exams from the 2013 Brazilian National Health Survey (PNS), seeking to assess their representativeness and precision. Methods: Two alternative proposals for constructing calibrated weights were performed based on post-stratification and raking methods. A comparison between the weights provided for the Laboratory Exams subsample and the two suggested weights was conducted through parameter estimates using the 2013 PNS subsample data. Additionally, seven measures were used to assess the performance of the proposed weighting systems. Results: The alternative post-stratification and raking weights produced generalizable estimates for the target population of the 2013 PNS, while the original weights did not. The alternative methods showed similar performance to the original method, with a slight advantage for raking in some evaluation measures. Conclusion: It is recommended that basic design weights be documented and included in the public-use data files of the PNS. Furthermore, it is suggested to cross-reference information between the sample and subsample of the 2013 PNS to enable the exploration of methods such as data imputation, aiming to obtain more accurate and representative estimates. These improvements are essential to ensure the quality and usefulness of PNS data in epidemiological and public health studies.
Analysis of the validity and reliability of the failure to thrive scale in older adults
Authors: Torres Julia Monzerrath Carranza , Delgado Jorge Raúl Palacios , Hernández Gaddy Natali Soberanes
Published: February 2025

Abstract Objective To estimate the psychometric properties (factor structure, validity and internal consistency) of an instrument developed to measure failure to thrive in the geriatric population. Method The sample consisted of 200 older adults, with an age range between 60 and 105 years, from three medical-geriatric care units in Morelia, Celaya and San Miguel de Allende (Mexico). The psychometric analyses used were factor analysis for validity and Cronbach's alpha for reliability. Results The reliability analysis showed an index of 0.913 (CI95% = 0.86-0.89) in the total score. In addition, the results indicate the factorial validity of the proposed instrument in seven dimensions: cognitive performance, depression, multimorbidity, functionality, social risk, primary caregiver and nutrition. Conclusions The validity and reliability of a failure to thrive scale in diagnosing this geriatric syndrome were obtained, and they suggest implications for development in the clinical and research field.
I Diretriz Brasileira de hipertensão arterial na diálise da Sociedade Brasileira de Nefrologia
Authors: Rodrigues Cibele Isaac Saad , Ferreira-Filho Sebastião Rodrigues , Moura Ana Flávia de Souza , Poli-de-Figueiredo Carlos Eduardo , Silva Dirceu Reis da , Polacchini Fernanda Salomão Gorayeb , Almeida Fernando Antônio de , Pinheiro Maria Eliete , Bezerra Rodrigo , Paula Rogério Baumgratz de , Peixoto Aldo José , Figueiredo Ana Elizabeth Prado Lima , Feitosa Audes Diógenes Magalhães , Machado Carlos Alberto , Amodeo Celso , Mion Junior Décio , Muxfeldt Elizabeth Silaid , Silva Giovanio Vieira da , Moura-Neto José Andrade , Pazeli Júnior José Muniz , Lotaif Leda Daud , Drager Luciano F. , Martín Luis Cuadrado , Bortolotto Luiz Aparecido , Bastos Marcus Gomes , Malachias Marcus Vinícius Bolívar , Moreira Marcos Vinícius Paiva Cavalcanti , Canziani Maria Eugenia Fernandes , Miranda Roberto Dischinger , Franco Roberto Jorge da Silva , Pecoits Filho Roberto , Mulinari Rogerio Andrade , Elias Rosilene Motta , Barroso Weimar Kunz Sebba , Nadruz Wilson
Published: February 2025

Resumo A hipertensão arterial em pacientes em diálise (HAD) tem alta prevalência, de pelo menos 80% ou mais, e seu manejo na prática do nefrologista ocorre de forma heterogênea e, frequentemente, empírica. Saber definir, conhecer a fisiopatologia, diagnosticar, acompanhar e tratar com mudanças no estilo de vida, e adequar os medicamentos anti-hipertensivos para alcançar a meta de pressão arterial (PA) recomendada, com vistas à redução da morbidade e mortalidade, requerem conhecimentos e abordagens específicos nos contextos da hemodiálise (HD) e da diálise peritoneal (DP). Este documento é a primeira diretriz da Sociedade Brasileira de Nefrologia, elaborada pelos departamentos de Hipertensão e de Diálise, que visa orientar os médicos que prestam assistência em centros de diálise a como manejar pacientes com HAD, de forma integral e individualizada, com base no julgamento crítico das melhores evidências científicas disponíveis e, quando essas são escassas ou indisponíveis, indicar a opinião de especialistas. Os diferentes temas abordados envolvem: a definição (PA pré-HD ≥ 140/90 mmHg e PA pós-HD ≥ 130/80 mmHg), epidemiologia e fisiopatologia; diagnóstico da HAD preferencialmente com medidas da PA fora do ambiente de diálise (PA ≥ 130/80 mmHg); avaliação complementar; metas pressóricas; tratamento não medicamentoso; uso dos anti-hipertensivos mais adequados; situações especiais; e complicações da HAD, predominantemente as cardiovasculares.
Jean-Christophe Le Coze e o estudo dos riscos sociotecnológicos
Authors: Hurtado Sandra Lorena Beltran , Simões Raoni Rocha , Almeida Ildeberto Muniz de , Vilela Rodolfo Andrade de Gouveia , Le Coze Jean-Christophe
Published: February 2025

Resumo Jean-Christophe Le Coze trabalha no Instituto Nacional de Ambiente Industrial e Riscos (INERIS) na França há mais de 20 anos. Começou sua carreira como engenheiro de segurança do trabalho, mas rapidamente migrou para as ciências humanas e sociais. Desde o início de sua carreira, foi introduzido à ideia de que os engenheiros poderiam incorporar os Fatores Humanos em suas visões e práticas de segurança. Ele passou quase um ano na Universidade Técnica de Delft, no Grupo de Ciências de Segurança. Após isso, ocorreu um acidente em uma fábrica de pirotecnia na França em 2003 e Jean-Christophe Le Coze, como encarregado da investigação, escreveu um relatório mostrando a importância dos Fatores Humanos e Organizacionais por trás desse evento. Foi um momento na França em que as plantas industriais de alto risco foram questionadas e estavam no centro da agenda política em termos de desenvolvimento de regulamentação adequada também. Desde então, ele contribuiu significativamente para o avanço do conhecimento na área de segurança. Uma de suas publicações, ‘Trinta anos de acidentes: a nova face dos riscos sociotecnológicos’, foi traduzida para o português e publicada em 2023. Esta entrevista destaca os principais conceitos do livro e os desafios atuais para a prevenção de acidentes.
Repair methods in peripheral nerves after traumatic injuries: a systematic literature review
Authors: Costa Naely Nobre , Santos Jennifer Ferreira dos , Aranha Maria Fernanda de Almeida Cavalcante , Coelho Erik William Farias , Paes Victor Leno Silva , Oliveira Rita de Cássia Silva de
Published: February 2025

ABSTRACT Purpose: To identify and describe the most used surgical repair methods for traumatic injuries to peripheral nerves, as well as highlight the causes of trauma to peripheral nerves and the most prevalent traumatized nerves. Methods: This is a systematic literature review using the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The searches were carried out in PubMED, in the time window from January 2018 to December 2022. Results: In total, 3,687 articles were collected, of which, after applying the inclusion and exclusion filters and analyzing the risk of bias, 34 articles remained. It was observed that the age of the injury and type of nerve repair strongly influence the recovery of patients. The most identified trauma repair procedures were neurolysis, direct suturing, grafting, and nerve transfer. Among these four procedures, direct suturing is currently preferred. Conclusion: Several repair methods can be used in peripheral nerve injuries, with emphasis on direct suturing. However, nerve transfer proves to be a differential in those cases in which repair is delayed or the first treatment options have failed, which shows that each method will be used according to the indication for each case.
Informal caregivers’ perceptions of their health activities during home hospitalization
Authors: Brito Pâmella Padilha , Santos Walterlânia Silva
Published: February 2025

ABSTRACT Objective: To understand the perceptions of informal caregivers with up to six months’ experience about their health activities during home hospitalization. Method: This qualitative study was conducted through interviews with primary caregivers of people registered with the Home Care Service in a region of the Federal District of Brazil who had been admitted for up to six months. Data were collected between July and October 2022. The data were analyzed using Bardin’s Thematic Content Analysis. Results: Three thematic categories were identified: health activities performed by caregivers, caregiver perspective on caring at home, and caregiver knowledge trajectory. Conclusion: The findings point to the need to implement a transition program from hospital to home care, as well as intersectoral actions and public policies that can provide a support network for caregivers and consider their individual needs.
Tuberculosis en la población privada de libertad: epidemiología y análisis espacial entre 2014 y 2020
Authors: Souza Pablo Cristiano de , Couto Rodrigo de Macedo , Lacerda Alec Brian , Silva Pãmela Rodrigues de Souza , Espinosa Omar Ariel , Lima Jaqueline Costa
Published: February 2025

Resumen Objetivo: Describir la epidemiología y distribución espacial de la tuberculosis en la población privada de libertad en el estado de Mato Grosso, en el período de 2014 a 2020. Método: Estudio descriptivo, con análisis espacial de la distribución geográfica de la tuberculosis. Se estimaron las incidencias, evaluando sus distribuciones en los municipios de Mato Grosso - Brasil a través del análisis de conglomerados espaciales Gi*. Resultados: 14,0% (n=1.003) de los 7.201 casos de tuberculosis notificados entre 2014 y 2020 en personas mayores ocurrieron en la población privada de libertad. La incidencia de tuberculosis en esta población pasó de 3.261,1 a 722,3 casos/100 mil habitantes entre 2014 y 2020. Personas de 18 a 39 años, de sexo masculino, de raza/color parda y con educación primaria incompleta fueron asociadas a la mayor ocurrencia de tuberculosis. Conclusión: Ee encontraron conglomerados de alto riesgo en las regiones central y sur del estado, cerca de municipios con mayor número de prisiones. El estudio contribuye a la formación de políticas públicas de salud y estrategias de control de la Tuberculosis.
The state of the art in body studies and their paradigms in the first decades of the 21st century
Authors: Baptista Tadeu João Ribeiro
Published: February 2025

Abstract The body is a recurring subject in several fields of knowledge, including philosophy, history, and education. Conceptions of the body tend to be analyzed in academic literature because they express how authors reflect on the relationship of the human being with themselves, others, and nature. Thus, the problem of this study is to identify the predominant epistemological approaches to the subject from 2001 to 2018. Regarding methodology, a quantitative-qualitative bibliometric study was conducted with education journals from 2001 to 2018, specifically those ranked A-1 by the Qualis CAPES system (2013-2016). The general objective of the study was to examine conceptions of the body in Brazilian education journals, approaching the paradigms of major scientific theories. Its specific objectives include: a) Examining the movement of knowledge production on the subject during the studied period; b) identifying the authors who published the most on body-related topics in education journals; c) analyzing how the epistemological debate on the body developed quantitatively; and d) showing how body conceptions manifest themselves in the different texts analyzed. The results show that among the studied journals, there is a predominance of phenomenological conceptions, followed by the postmodern movement, positivism, and dialectical materialism, respectively. In conclusion, the phenomenological tradition was found to stand out in the studied texts, demonstrating a concern with looking at the human being as a totality.
A litigiosidade entre estados latino-americanos e caribenhos em mecanismos de solução de controvérsias e o sistema análogo do MERCOSUL
Authors: Jacintho de Oliveira Adriano Junior
Published: February 2025

O atual mecanismo de solução de controvérsias internacionais do Mercosul tem sido frequentemente criticado sob o argumento de subutilização do sistema, tendo tratado de poucos casos contenciosos entre 1999 e 2012, havendo críticas sobre a qualidade das decisões proferidas e sua contribuição para o fortalecimento ou descrédito do Mercosul. Esta pesquisa buscará, através do método comparativo, valendo-se das análises quantitativa e qualitativa, considerar a atividade jurisdicional do Mercosul em relação a outros mecanismos de solução de controvérsias internacionais latino-americanos e o sistema caribenho, bem como a litigiosidade dos países integrantes destes sistemas de integração em sistemas multilaterais de solução de controvérsias.
The Relationship between Market Depth and Liquidity Fragility in the Treasury Market
Authors: Meldrum Andrew C. , Sokolinskiy Oleg
Published: February 2025

Analysis of market liquidity often focuses on measures of the current cost of trading. However, investors and policy-makers also care about what would happen to liquidity in the event of an adverse shock. If liquidity were to deteriorate rapidly at times when investors were seeking to rebalance portfolios, this could amplify the effects of shocks to the financial system even if liquidity is high most of the time. We examine the potential for such fragility of liquidity in the Treasury market. We show that a reduction in the availability of resting orders to trade (``market depth") increases liquidity fragility, likely because lower depth increases the dependence of low trading costs on prompt replenishment of resting orders. Our results apply to all major benchmark Treasury securities individually, which enables us to establish analogous conclusions for market-wide liquidity fragility.
Enfrentamento do Luto pela Teoria Motivacional do Coping: Pandemia Covid-19
Authors: Souza Almeida Caroline , Aparecida da Silva Suélen , Duarte Pino Freitas Wellin Ketlyn , Da Silva Andressa Melina Becker
Published: February 2025

A COVID-19 tem sido considerada uma crise epidemiológica e psicológica. Ao deparar-se com inúmeras perdas, o luto acontece e seu enfrentamento se faz necessário. Assim, objetivou-se analisar o coping, ou seja, o processo de enfrentamento diante do estressor (morte) durante a construção do luto para os participantes. Aplicou-se um questionário online, tendo 111 participantes, acima de 18 anos, de ambos os sexos. A maioria dos participantes utiliza coping mal adaptativo, sendo desamparo, fuga e isolamento as famílias de coping mais usadas. Mulheres, pessoas mais velhas, com maior escolaridade e melhores condições socioeconômicas apresentam coping mais adaptativo. O luto simbólico pela perda da saúde, emprego e estudos no período da pandemia esteve mais associado ao coping mal adaptativo. Percebe-se a importância da atuação de psicólogos para orientação de formas adaptativas de coping para lidar com o luto durante a pandemia.
Educação Escolar no Paraguai: análise da atuação de professores homens com pessoas com deficiência
Authors: Kashiyama Pessoa Matheus , Peres Gonçalves Josiane
Published: February 2025

O estudo teve por objetivo averiguar como é a educação especial paraguaia e qual a visão da comunidade escolar de Salto Del Guairá – PY acerca da atuação de professores homens com crianças com deficiência. A pesquisa de campo foi realizada mediante gravação de entrevistas com uma Supervisora Pedagógica municipal, responsável por 17 instituições escolares de Salto Del Guairá, e uma mãe que reside no mesmo município e tem uma filha com deficiência, que estudou com um docente masculino em uma instituição inclusiva brasileira, em um município que faz fronteira com o Paraguai. Os resultados evidenciam que a Educação Especial paraguaia tem uma proposta que prevê o atendimento a pessoas com deficiência, mas na prática acaba não se concretizando, devido à falta de infraestrutura. A cultura paraguaia reproduz alguns padrões sociais de gênero e, desse modo, foi identificado um certo receio dos familiares quanto a atuação do docente masculino com crianças com deficiência.
Pandemia e Velhices: práticas de saúde e produções de conhecimento
Authors: Krupek Lirian Simões , Da Silva Paula Marques
Published: February 2025

Visto que a população idosa compõe o grupo de risco para Covid-19, o artigo teve como objetivo mapear a produção de artigos científicos, nas bases de dados Scielo, Lilacs e Pepsic, que articulam envelhecimento e Covid-19, no âmbito das políticas públicas de saúde da pessoa idosa. Foi uma revisão integrativa que, reunindo 26 trabalhos, analisou quatro campos por eles explorados, buscando responder aos objetivos da pesquisa, ou seja, articulando práticas de cuidado a velhas e velhos durante a pandemia com determinantes sociais de saúde e marcadores sociais que atravessam essas vidas. Reconhecemos a presença dessa articulação em muitos trabalhos, porém observamos ainda a necessidade de outros em iniciar esse movimento articulatório, que diz de uma posição ética. Este trabalho agrupa materiais para a assistência à população velha com protocolos e possibilidades, seja na criação de novas estratégias ou na utilização destas, adaptando aos diversos contextos de atuação.
Guest Editorial: Road safety advocacy - a legitimate role for occupational therapists?
Authors: Randall Lee
Published: February 2025

http://dx.doi.org/10.17159/2310-3833/2018/v48n3a1
The facilitators and barriers encountered by South African parents regarding Sensory Integration occupational therapy
Authors: Smit Jacintha , De Jongh Jo-Celene , Cook Ray Anne
Published: February 2025

Introduction: Differences in parent perceptions regarding occupational therapy using a sensory integration approach to treatment have been noted. The various factors that may influence these perceptions, and how the perceptions may ultimately influence the outcome of the intervention for the child and family were questioned. A phenomenological study revealed a progression that all parents perceived and experienced as the "before", "input" and "after" phases of when their child received occupational therapy/sensory integration (OT/SI). This article focuses specifically on the "input" phase of OT/SI intervention.
Method: Participants in this study were nine parents of children with difficulties processing and integrating sensory information, who live in the Western Cape, South Africa. Using a qualitative, phenomenological approach, data were collected during face-to-face interviews, participant observation and researcher's field notes.Â 
Findings: The main theme related to this phase of analysis was "Just suddenly everything made so much sense". For most participants, this phase brought to light a better understanding of sensory integration disorder (SID), also known as Sensory Processing Disorder (SPD) and OT/SI. Data analysis identified two subthemes that catalysed expansion in most participants' understanding, which were the role of the occupational therapist, and the OT/SI intervention process. Within these subthemes, the facilitating factors and barriers of OT/SI intervention emerged.
Conclusion: Insight gained from the participants' recommendations and interpretation of findings allowed recommendations to be made within the OT/SI intervention received, in an attempt to overcome the barriers and promote the facilitators that will make a difference to OT/SI in South Africa.Â 
Key words:
Sensory integration; sensory integration disorder (SID); sensory processing disorder (SPD); parent(s) perceptions; facilitators; barriers.
A survey of occupational therapists' involvement in facilitating self-employment for people with disabilities
Authors: Monareng Luther Lebogang , Franzsen Denise , Van Biljon Hester
Published: February 2025

Background: In South Africa, occupational therapists are involved with the facilitation of people with disabilities ability to work, but the high unemployment rate in the country affects placement opportunities. Utilising the option of self-employment is a way of addressing this problem.
Objective: To explore the attitude of South African occupational therapists about facilitating self-employment with their clients, their awareness of available resources that support self-employment, if therapists are offering such intervention and what they perceive their role to be within the field.
Method: The study used a quantitative cross-sectional descriptive survey design.
Results: A positive attitude (90%) and good awareness of available resources (74%) existed amongst participating occupational therapists. Occupational therapy practices did not offer self-employment facilitation in an evidence-based manner. Therapists believed their roles were undefined within the field of self-employment, and their training did not equip them to offer such intervention.
Conclusion: Occupational Therapists agree that self-employment is a good work option for people with a disability and are aware of resources that support such endeavours. The therapeutic practice and role definition is lacking. Occupational therapists have to create evidence that enables transformational and afro-appropriate interventions, for example, self-employment for people with disabilities within their profession.
Key words: Self-employment, Unemployment, SMME (Small, medium and micro enterprise) and PWDs (People with disabilities)
miR-542-3p attenuates corticosterone-induced hippocampal neuronal damage in depressive mice by modulating PTEN/AKT/GSK3β/β-catenin pathway
Authors: Yang Ningbo , Li Jie , Hu Hongxia , Wang Xujiang
Published: February 2025

Depression is a common psychological disease, and nerve injury is the key link of depression. The molecular mechanism involved in this link needs to be explored. miR-542-3p can reduce the degree of hippocampal neuronal damage in rats, but its mechanism in the neural damage of depression is still unclear. HT-22 cell injury was induced by corticosterone (CORT). After overexpression or knockdown of miR-542-3p, CORT-induced HT-22 cell injury was tested by Cell Counting Kit-8 (CCK-8) assay, LDH assay and flow cytometry. Inflammatory and oxidative stress indicator levels were analyzed by kit and flow cytometry. The target genes of miR-542-3p were obtained by database analysis, and the targeting relationship between miR-542-3p and phosphatase and tensin homolog (PTEN) was explored based on dual luciferase assay. After PTEN overexpression or application of AKT pathway agonist MK-2206, the degree of cell damage, inflammation and oxidative stress were detected again. CORT was used to induce depression in mice. Pathological changes of brain tissue structure and neuronal survival were observed by pathological staining. The miR-542-3p, PTEN and AKT/GSK3β/β-catenin pathway protein levels in vivo and in vitro were detected by qRT-PCR and Western blot. Overexpression/knockdown of miR-542-3p alleviated/aggravated CORT-induced cell injury, inflammation and oxidation levels in HT-22 cells (P < 0.05). Meanwhile, overexpressed miR-542-3p can reduce neurological damage of mice. miR-542-3p can target PTEN, and it can trigger the AKT/GSK3β/β-catenin pathway by targeting PTEN expression to reduce CORT-induced nerve injury (P < 0.05). miR-542-3p can reduce CORT-induced hippocampal neuronal damage by targeting PTEN and activating the AKT/GSK3β/β-catenin pathway.
An Analysis of the Relationship between the Number of Children and Employment Choices among Married Women
Authors: Linjuan Cai
Published: February 2025

This study examines the impact of the number of children and external factors on married women’s employment choices using probit models and Instrumental Variable (IV) regression with data from the International Social Survey Programme: Family and Changing Gender Roles IV. The analysis includes both an “employment choice” model and a “working hours” model to assess how fertility influences labour market outcomes. To address endogeneity, the study employs an IV measuring perceived restrictions on parental freedom, justified by the Second Demographic Transition Theory. While this variable reflects fertility preferences, it does not directly influence employment beyond its effect on child count, ensuring exogeneity. First-stage tests confirm relevance, with F-statistics exceeding the empirical threshold. Results show that having more children significantly increases women’s self-employment rates while reducing their likelihood of being employed by companies. IV regression further reveals that the effect of childbearing on employment varies by education level and husband’s employment status. Additionally, when the number of children increases, husbands are more likely to seek employment. These findings contribute to the literature on fertility and women’s employment, highlighting the need for family-friendly policies and cultural shifts to support women’s workforce participation while balancing family responsibilities.
The Effect of The Bank Indonesia Development Program on The Development of Agribusiness MSMEs
Authors: Kirani Asti , Aritonang Marisi , Wanti Fitrianti
Published: February 2025

Background: Business digitization skills are important for business actors to have, especially in the digital era. Therefore, it is important to improve their skills in building a better economy. The Bank Indonesia development program is one solution to accelerate the digitalization of MSMEs in Indonesia. Previous research on MSME development programs rarely focuses on the agribusiness sector. Purpose: This research examines how Bank Indonesia's training and mentoring for MSMEs impacts the development of agribusiness MSMEs. Design/methodology/approach: Data was collected by distributing questionnaires with a total of 50 respondents. Primary data was processed using Structural Equation Modeling-Partial Least Square (SEM-PLS) with the competency variable as an intervening variable. Findings/Result: The research results show that training and mentoring significantly affect the development of agribusiness MSMEs. Training and mentoring also indirectly affect the development of agribusiness MSMEs through competency as an intervening variable. Conclusion: agribusiness MSME actors who participate in training and mentoring must have competence in attitudes, knowledge, and skills. Furthermore, the more competent agribusiness MSMEs are, the better the development of agribusiness MSMEs will be, namely increasing income, strengthening competitiveness, and expanding market reach. Originality/value (State of the art): training and mentoring for Agribusiness MSMEs are factors that influence the development of Agribusiness MSMEs.
Keywords: MSMEs, development programs, agribusiness, training and mentoring, business digitization
Corporate Marketing Change Management at PT Wijaya Karya (Persero) Tbk
Authors: Olivia Miftha , Ratnawati Anny , Shalihati Fithriyyah
Published: February 2025

Background: The construction industry plays a vital role in Indonesia's GDP. However, the Covid-19 pandemic has negatively impacted this sector, prompting companies to adapt. PT Wijaya Karya (WIKA) faces marketing challenges, including issues with decentralization and lack of focus on key customers, necessitating organizational changes.Purpose: This research examines how the application of Kotter’s 8 Step Change Model and the ADKAR Model can address WIKA’s marketing challenges by fostering structured adaptation. These models were selected for their ability to navigate organizational change during periods of disruption, such as the pandemic, which intensified decentralization and strained customer focus in the construction sector.Design/methodology/approach: This study employs a descriptive qualitative approach through interviews with five internal WIKA stakeholders, from senior vice presidents to corporate marketing staff, and one external expert for validation, supplemented by an analysis of internal reports and strategic plans.Findings/Result: The findings show that the integration of Kotter’s 8 Step Change Model, the ADKAR Model, and Key Account Management significantly improves marketing performance and strengthens relationships with key customers. Enhanced employee engagement, intensive training, improved inter-division coordination, and the adoption of modern technologies also contribute to operational efficiency and sustainable company growth.Conclusion: Integrating Kotter’s 8 Step and ADKAR Models with Key Account Management at WIKA offers an effective framework for overcoming decentralized marketing, providing a replicable strategy for companies facing similar challenges to drive strategic growth.Originality/value (State of the art): This research highlights the importance of integrating change management models with Key Account Management practices to enhance both marketing performance and customer relationships, ultimately supporting sustainable business growth.
Keywords: ADKAR, change management, key account management, kotter 8 step change model, marketing decentralization
The Impact of Borrowing and Lending Account Growth on The Profitability of Fintech Lending Companies
Authors: Puspitasari Nabila Cahita , Achsani Noer Azam , Irawan Tony
Published: February 2025

Background: Fintech lending or online lending services is one of the innovations in the financial industry that is growing rapidly and has a significant impact on the economy in Indonesia, especially for MSMEs. The increase in outstanding online loans in Indonesia is because online loan services are considered easier to apply for than traditional financial services. Purpose: This study analyzes the impact of increasing borrower and lender accounts, bad loan risk, and macroeconomic conditions on the profitability of fintech lending companies in Indonesia over the past five years.Design/methodology/approach: This study uses monthly time series data with a research period from January 2019 to December 2023. The type of data used in this study is secondary data obtained from the official websites of Bank Indonesia, OJK, and S&P Global. This study uses the Autoregressive Distributed Lag (ARDL) analysis method using E-views12 software.Findings/Results: The results show that the firm's profitability tends to increase in the short run when the number of lender accounts increases. At the same time, the non-performing loans, inflation, and interest rates decrease. In the long run, borrower account growth, lender account growth, and Purchasing Manager's Index (PMI) positively affect the profitability of fintech lending companies. The growth of Fintech Lending in Indonesia has experienced rapid growth in the past 5 years, especially in the period 2021-2022. The outstanding online loans increased dramatically due to the COVID-19 pandemic. The development of borrower and lender accounts can positively impact company profitability but also increase the risk of bad loans.
Keywords: Fintech Lending, Return on Assets (ROA), Non-Performing Loan (NPL), Purchasing Manager’s Index (PMI), Autoregressive Distributed Lag (ARDL)
Roadmap for Human Resources Development at XYZ University
Authors: Damayanti Nurlia Eka , Aprilita Aprilita , Nugroho Sanjayanto , Widyaningsih Dhina Sri
Published: February 2025

Background: Human resources constitute a pivotal asset for organizations in achieving their strategic objectives. The presence of high-quality human resources offers a competitive advantage in navigating the complexities of the current era of disruption. Purpose:This research seeks to establish a human resource development roadmap for XYZ University. Design/Methodology/approach: Data collection was undertaken through interviews with subject matter experts familiar with the organizational dynamics at XYZ University. The collected data were subjected to analysis using descriptive and interactive model methodologies. The proposed human resource development roadmap for XYZ University is delineated into two temporal phases: short-term (2024) encompassing nine strategies and long-term (2025–2026) comprising five strategies. Finding/Result: This roadmap is structured around three primary categorical approaches: motivation, leadership, and organizational structure. Within these categories, a series of human resource development strategies were articulated to address both short-term and long-term organizational requirements. Conclusion: The short-term strategies primarily focus on the assessment and enhancement of employee motivation, while the long-term strategies are directed towards the refinement of organizational systems and leadership approaches in accordance with evolving needs.
Keywords: human resources, strategic objectives, interactive model, development roadmap, university
STEPanizer calibration v1
Authors: Hernandez Leidyanne , Fernandes-Santos Caroline
Published: February 2025

STEPanizer is a software designed for the stereological evaluation of digital images acquired from microscopes and macroscopic devices. It allows the application of the most essential stereological parameters, such as volume, surface, length, and number. The user must configure a test system that is projected onto the digital image to be analyzed. Counting is made by the observer and computed into the software, which then tabulates the data and exports it to Excel. The operator must enter the stereological formulas into Excel to obtain the result. STEPanizer is helpful because it standardizes the creation of test systems. However, before all that, the primary step is to calibrate the software to obtain proper data.
High-throughput 96-well plate-based porcine antibody isolation protocol v1
Authors: Byrne John , Bourne Christina , Eguiluz Sitka , Langel Stephanie , Crisci Elisa
Published: February 2025

This protocol describes a modified column chromatography technique to isolate both IgG and IgA from pregnant/lactating swine to use in a variety of immunoassays. This high throughput method allows for both a rapid and consistent isotype yield from individual animals and different tissue samples.
A Heuristic for Integrating Sense of Place Into Ocean Governance
Authors: Duggan Joe , Cvitanovic Christopher , Van Putten Ingrid , Clement Sarah
Published: February 2025

Sense of place (SoP) is a powerful yet underutilised social value with significant potential to improve collaboration and inclusivity in ocean governance. Recent evidence, however, has shown that a range of barriers prevent the routine integration of SoP in this space. To help overcome this, this commentary proposes a preliminary heuristic—or rules of thumb—that can help guide researchers and practitioners to help them incorporate SoP into ocean governance. The heuristic emphasizes fostering collaboration, inclusivity, and shared understanding among diverse stakeholders and non‐academic actors. It advocates for the co‐production of knowledge across disciplines and institutions, iterative reflexivity to address positionality, and the creation of shared definitions and measures of SoP tailored to specific contexts. It explores balancing a broad conceptual understanding of SoP with localized tangible applications to ensure relevance and impact. Celebrating “bright spots,” or successful instances where research has informed policy, is also highlighted as a way to inspire and support the utilization of SoP in management decisions. By utilizing SoP as a relational tool, we posit that ocean governance practitioners can enhance trust, promote more meaningful stakeholder engagement, and align diverse perspectives toward common goals, thus building more inclusive and collaborative management practices.
STATIONARY UNMANNED AERIAL VEHICLE COUNTERMEASURE DEVICES: PRACTICAL ASPECTS OF THEIR APPLICATION
Authors: Ignatjevs Olegs , Korklis Andrejs
Published: February 2025

The aim of this study is to investigate the limitations of using unmanned aerial vehicles (UAVs), to identify the legal and practical aspects of countermeasures, and to find the most suitable technical solutions for the State Border Guard operations. To achieve this objective, the following tasks were set: to examine the regulatory framework related to the use of UAVs, to identify the legal limitations of UAV usage; to investigate practical examples within the State Border Guard operations where technical solutions for combating UAVs were necessary; to describe the UAV countermeasure devices available on the market, comparing them with solutions already in use in Latvia; to propose potential pathways for developing the technical base in the field of UAV countermeasure devices. To accomplish these tasks, the following research methods were applied: the monographic method, document analysis, the logical-constructive method, and surveys. The structure of the work consists of four chapters: the first chapter examines the relevant legal regulations, the second chapter explores practical examples within the State Border Guard operations where UAVs have been used unlawfully, the third chapter analyzes the technical parameters and operating principles of UAV countermeasure devices, and the fourth chapter investigates the technical solutions of UAV countermeasure devices available on the market. The study concludes with a section of conclusions and proposals.
COLLECTIVE EXPULSION OF MIGRANTS AND ITS ETHICAL AND LEGAL ASPECTS IN BORDER MANAGEMENT
Authors: Krutova Ērika
Published: February 2025

This publication provides a multi-faceted approach, bringing together ethical and legal aspects of migrants’ collective expulsion that have so far been insufficiently studied. The aim of the publication is to study the phenomenon of migrants’ collective expulsion from borders, or “pushbacks”, by analysing the ethical considerations and legal effects, as well as providing practical recommendations for policy-makers and human rights defenders.To achieve this aim, the author analyses the ethical aspects of migrants’ collective expulsion by examining human rights and humanitarian reasons, studies the legal frameworks and international conventions that govern the practice of collective expulsion, compiles precedents and court judgements that illustrate the legal effects for states and concludes with recommendations for more humane and legally compliant border management practices.Quantitative methods, analysing data and documents, case law and precedents are used in the study. The results of the study indicate that, firstly, collective expulsion violates fundamental human rights and humanitarian principles, creating deep moral dilemmas; secondly, states that engage in collective expulsion risk violating international law, which can lead to lawsuits and sanctions; thirdly, migrants who are collectively excluded experience severe psychological and physical disruptions that have long-term effects on their well-being and generate hatred. The author concludes that there is a need to promote more humane and legally correct border management practices based on respect for human dignity and international legal standards.
THE ISSUE OF USING TECHNICAL EQUIPMENT FOR THE DETECTION OF FORGED DOCUMENTS IN THE FIRST AND SECOND LINE OF CONTROL
Authors: Smirnovs Aigars , Pokule Inta
Published: February 2025

The study examines issues related to technical equipment for document verification and detection of forged documents in the first and second line. Today, counterfeiters use increasingly innovative methods and equipment, which necessitates the improvement of technologies for identifying counterfeit documents. The novelty of the research lies in the comparative analysis of the work efficiency of technical equipment in both the first and second line, with the aim of detecting and detecting various types of forged documents. The goal is to analyze the effectiveness of currently used technical equipment and the problems that can be encountered in the study and detection of forged documents. The procedure itself during border control is analyzed for them, as well as solutions to problems are given. The main tasks are the specifics and available functions of the existing technical equipment, solving problems in the use of these technical equipment, offering solutions.
PROBLEMS OF COMBATING MONEY LAUNDERING IN THE STATE BORDER GUARD
Authors: Kolendovičs Andris
Published: February 2025

Money laundering is one of the offences included in a list of ten crimes (known as "Eurocrimes") on which the European Union will focus most of its attention. In this article, the author reviews the definitions of the term "money laundering", describes the competence of law enforcement institutions combating money laundering, including the one of the State Border Guard in cases when money laundering has been detected, analyses relevant statistical data and defines the problems of combating money laundering in the State Border Guard. The aim of the study is to analyse the concept of money laundering, to identify law enforcement institutions that combat money laundering, to look at possible problems faced by the State Border Guard in combating money laundering. The object of the study is money laundering, the subject of the study - problems of combating money laundering in the State Border Guard. The methods used in the study are: comparative method, semantic method, legal analysis method.
DOCUMENT EXAMINATION ISSUES AT BORDER CROSSING POINTS AND POSSIBLE SOLUTIONS
Authors: Rižakova Kristīne , Agafonovs Eduards
Published: February 2025

Document examinations conducted by the Latvian Border Guard Service at border crossing points are important for ensuring security and control of people crossing the state border. However, existing border check processes often face challenges such as traffic congestion, slow border check speeds, human errors, and the risk of document forgery. These issues can lead to delays, reduce the efficiency of border checks, and increase the risk of travelers with forgotten or illegal documents crossing the state border of the Republic of Latvia. This study aims to analyze the existing problems in document examination and identify possible solutions. The research used several methods, including analysis of documents and normative acts and interviews with experts who regularly conduct document examinations at border crossing points. The study's objectives are to examine current problems and challenges, collect and analyze experts' opinions concerning document examination.