bluuebunny/crossref_metadata_2025 huggingface dataset:
The World Beyond Superstrings
Authors: Vegt Wim
Published: August 2018

In this manuscript a new theory will be presented which offers answers at dimensions smaller than Planck’s length and smaller than the dimensions of “Superstrings”. To find this theory we have to find back a lost path in History. To find back the fundaments of ”Gravitational-Electromagnetic Confinement” which reveals the secrets of light which will take us beyond Relativity and which will describe the interaction between gravity and light in a different way than in General Relativity. A theory that will not be build on existing theories but a theory which will offer new roads to new discoveries and which will reach further beyond “Superstrings” than the roads which already do exist.
Spanning trees with a given number of leaves
Authors: Nguyen Thinh D.
Published: August 2018

We prove the hardness of yet another problem in graph theory with a flavor of computer games, namelyTerra Mystica. Much like works of Demaine and others, we abstract the computer game to have a mathematicalmodel which is in the form of combinatorial optimization. A reduction from 3Sat shows that our claim holds.
DAMPAK PENGEMBANGAN MODEL PEMBELAJARAN TERHADAP PENGUASAAN TEKNIK DASAR SMASH BOLA VOLI
Authors: Kasih Indra
Published: August 2018

Penelitian ini difokuskan pada Pengembangan model pembelajaran Latihan smash Bola Voli di Fakutas Ilmu Keolahragaan Universitas Negeri Medan. Penelitian ini adalah Mengembangkan Model Pembelajaran Latihan smash untuk Meningkatkan Kemampuan Teknik Smash bola Voli di Fakultas Ilmu Keolahragaan Universitas Negeri Medan. Metode Penelitian yang dipakai adalah penelitian dan Pengembangan (R&D). Hasil penelitian ini telah memenuhi syarat validitas, homogenitas, normalitas, efektifitas dan telah mampu meningkatkan hasil belajar mahasiswa PJKR regular Faukultas Ilmu Keolahragaan Universitas Negeri Medan. Dari uji coba diperoleh kinerja smash bola voli berdasarkan faktor pembelajaran bahwa kelompok eksperimen postes (model baru) dan kelompok ekpserimen pretes (model lama) keterampilan smash bola voli kelompok eksperimen postes yaitu skor terendah 12 dan tertinggi 16, sedangkan pada kelompok eksperimen pretes, hasil kemampuan smash bola voli diperoleh skor terendah 10 dan skor tertinggi 15. Efektifitas pengembangan model pembelajaran hasil pembelajaran model lama dan baru mengalami peningkatan dari 73,33% menjadi 82,50%. Sehingga dapat disimpulkan pembelajaran model baru lebih efektif dari pembelajaran model lama. Hasil belajar setiap indikator penilaian pembelajaran model baru lebih efektif dari pembelajaran model lama. Hasil belajar (rata-rata dari keseluruhan indikator) yang diperolehpun mengalami peningkatan dari 66,74% menjadi 88,84%. Sehingga dapat disimpulkan pembelajaran model baru lebih efektif dari pembelajaran model lama.
PENGARUH KECELAKAAN KERJA TERHADAP PRODUKTIVITAS KERJA KARYAWAN PT. MARUKI INTERNATIONAL INDONESIA
Authors: suradi
Published: August 2018

Penyebab kecelakaan kerja ada empat faktor diantaranya: Faktor nasib dari par karyawan, faktor lingkungan fisik pada karyawan, seperti mesin, gedung,ruangan, peralatan, faktor kelalaian manusia dan faktor ketidak serasian kobinasi faktor-faktor produksi yang di kelolah dalam perusahaan. Metode penelitian yan digunakan adalah observasi yaitu pengambilan data dengan meninjau dan meneliti secara langsung hal-hal yang berkaitan dengan objek penelitian. Interview yaitu dengan mengadakan wawancara secara langsung dengan kepala seksi, karyawan maupun pihak-pihak yang berhubungan dengan keselamatan dan kesehatan kerja.Hasil penelitian dari nilai tabel F pada ᾳ 5% ; di mana dbreg = 2 dan dbres = n – 3 = 9 adalah 2,262 (Interpolasi). Dengan demikian nilai hitung F > nilai tabel F, maka H0 di tolak,artinya koefisien regresi signifikan Bahwa lingkungan kerja menpunyai hubungan sangat erat dan mempunyai pengaruh yang signifikasi antara pengaruh kecelakaan akibat alat pelindung diri dan akibat kelalaian manusia terhadap lingkungan kerja.
TOPONOMI KECAMATAN BANYUWANGI, SINGOJURUH, DAN ROGOJAMPI
Authors: mursidi agus , Soetopo Dhalia , (Prosiding Seminar Nasional FKIP Univeritas PGRI Banyuwangi
Published: August 2018

The branch of science that studies the naming of places is called toponimi. Toponimi's research contributes greatly to the historical understanding of society and provides a very useful geographic reference system in society. Banyuwangi Regency has a relatively unique area because it consists of coastal / marine, terrain and mountain areas. Its inhabitants have ethnic diversity namely Osing (Banyuwangi original ethnic), Java, Madura, Bugis and Bali. This is an indication of the naming of places that have their own characteristics.The research was done by descriptive method which was done with the research phases which is planned is phase I of toponomic study of 24 districts. The taking is done by interviewing 3 resource persons. The first interview was conducted with the local government. Furthermore, two community leaders were selected based on information obtained from the local government. The interview was conducted by 2 teams in which 1 researcher was accompanied by 1 surveyor. The interview process is equipped with a tape recorder and documentation using a camera. Information on the results of interviews will then be organized into categories and analyzed using triangulation method.
Perception is everything: how people see ecosystem services can guide management and modeling efforts
Authors: Open Communications for The Ocean OCTO
Published: August 2018

In their paper, the authors described ways to determine which ecosystem services matter most to community wellbeing through participatory mapping, key informant interviews, and semi-structured interviews. Once the list of ecosystem services was determined, the authors used a questionnaire to elicit the perceptions of various user-groups. By binning users into groups (like those that directly depended on functional ecosystem services for their livelihoods), the authors could compare and contrast how people perceived the state and importance of different aspects of the estuary. Importantly, the authors included closed and open-ended questions in their survey to determine how people surmised potential management interventions would impact the environment and the wellbeing of them and their families.
Watkins & Goodwin Sacrifices 2019 Pre-Print
Authors: Watkins Hanne M
Published: August 2018

Environmental problems such as climate change present formidable psychological barriers because they require action now to produce advantageous outcomes many years hence. Accordingly, it is important to understand how to motivate moral concern and a sense of moral obligation towards future generations. Some past research has explored whether encouraging “intergenerational reciprocity” might increase such a sense of obligation. However, this research is limited either in its robustness, or in its direct applicability to general environmental problems such as climate change. In the present research with U.S. residents recruited through Amazon Mechanical Turk, we explored a novel means of invoking this sense of intergenerational reciprocity: Asking individuals to reflect on the sacrifices made by previous generations. An initial correlation study showed that perceptions of past generations’ sacrifices correlated with a sense of moral obligation towards future generations. Subsequent experimental studies showed that reflecting on such sacrifices increased a sense of moral obligation towards future generations. A within-paper meta-analysis suggests that the overall effect is Cohen’s d = .352, 95% CIs [0.227, 0.477]. In all studies, this effect was statistically mediated by gratitude. However, this sort of reflection carries a potential downside – it also generates a feeling of being unworthy of past generations’ sacrifices, which suppresses the overall effect on moral obligation. And it is limited in not directly translating into pro-environmental behavioral intentions and attitudes. In sum, the present studies report a novel means of invoking intergenerational reciprocity, while also calling attention to limiting factors that warrant further attention.
Women in Science: Surpassing Subtle and Overt Biases through Intervention Programs
Authors: Bondarescu Ruxandra , Balakrishna Jayashree , Moran Christine Corbett , De Silva Anuja
Published: August 2018

This study discusses factors that keep women from entering science and technology, which include social stereotypes that they struggle against, lack of maternity leave and other basic human rights, and the climate that makes them leave research positions for administrative ones. We then describe intervention processes that have been successful in bringing the ratio of women close to parity, compare different minorities in the US, and also consider data from India, Western and Eastern Europe. We conjecture that programs that connect the different levels of education are needed in addition to hiring more women, providing them with basic human rights from when they begin their PhD onwards and promoting support networks for existing employees. The authors of this paper hail from Sri Lanka, Romania, India, and the United States. We hold undergraduate and graduate degrees in physics or chemistry from the United States, India and Switzerland. Our conclusions are based on data that is publicly available, on data we have gathered, and on anecdotal evidence from our own experience.
Scene layout priming relies primarily on low-level features rather than scene layout
Authors: Shafer-Skelton Anna , Brady Timothy F.
Published: August 2018

The ability to perceive and remember the spatial layout of a scene is critical to understanding the visual world, both for navigation and for other complex tasks that depend upon the structure of the current environment. However, surprisingly little work has investigated how and when scene layout information is maintained in memory. One prominent line of work investigating this issue is a scene priming paradigm (e.g., Sanocki & Epstein, 1997), in which different types of previews are presented to participants shortly before they judge which of two regions of a scene is closer in depth to the viewer. Experiments using this paradigm have been widely cited as evidence that scene layout information is stored across brief delays and have been used to investigate the structure of the representations underlying memory for scene layout. In the present experiments, we better characterize these scene priming effects. We find that a large amount of visual detail rather than the presence of depth information is necessary for the priming effect; that participants show a preview benefit for a judgment completely unrelated to the scene itself; and that preview benefits are susceptible to masking and quickly decay. Together, these results suggest that “scene priming” effects do not isolate scene layout information in memory, and that they may arise from low-level visual information held in sensory memory. This broadens the range of interpretations of scene priming effects and suggests that other paradigms may need to be developed to selectively investigate how we represent scene layout information in memory.
If At First You Don't Succeed... Reconsider: Attainability Cues and Adaptive Disengagement
Authors: Townsley Christine
Published: August 2018

Peoples’decisions to persist or disengage from a goal are essential to successful self-regulation. Whenpeople encounter unattainable goals, persistence can cause psychological and physicaldistress. The present study hypothesizes that variation in task persistence (an individual’s decisions to continue in a particular task or behavior) is due in part to peoples’ evaluations of the task’s attainability. In a within subjects design, participants were given two sets of challenging cognitive puzzles with several unsolvable items. The first set of puzzles had no cue about attainability, but the second set included an answer option indicating that the correct answer was not present. As predicted, the attainability manipulation had a significant effect on persistence, with participants spending less time on puzzles when they were cued that they might be unattainable. Most significantly, participants high in self-control spent less time on impossible puzzles in the un-cued condition, an effect opposite our prediction and the literature consensus.
The changing trend of head injury at Bir Hospital
Authors: Khadka Nilam K
Published: August 2018

Not Available.Nepal Journal of Neuroscience, Volume 14, Number 1, 2017, Page : 1-1
Lhermitte-Duclos Disease: A case report
Authors: Kafle Prakash , Shilpakar Sushil K , Sharma Mohan R , Sedain Gopal , Pradhanang Amit K , Ghimire Ram Kumar , Rajbhandari Binod
Published: August 2018

Available with full text.Nepal Journal of Neuroscience, Volume 14, Number 1, 2017, Page: 28-31
The effects of top pruning on growth and production of conelets and cones in Pinus brutia Ten seed orchards of different ages
Authors: Alan Murat , Kaplan Selim , Ezen Turgay , Sabuncu Rumi
Published: August 2018

In economic and biological terms (rapid growth, the ability to produce seeds at an early age, etc.) Pinus brutia Ten. is one the most important forest tree species in Turkey. Considerable progress has been made in Pinus brutia Ten. breeding program and both phenotypical and according to the results of progeny trials, totaling 615-hectare seed orchardshas been established. Pinus brutia Ten. seed orchardshas reached 43% of the total orchard area and covered the largest area.
To acquire information on the management of seed orchards, top pruning has been carried out on three Pinus brutia Ten. seed orchards of different ages (old, middle-aged and young). Two top pruning regimes were applied in these three seed orchards, once in 2008 to the old orchard, while a single topping regime was applied in 2008 and 2012 to the middle-aged and young orchards.Each year, the height, diameter at breast height, and bi-directional crown diameter were measured, and all conelets and cones on ramets were counted beforeand after pruning.
At the end of four years, control ramets in old and young seed orchards had higher values of height, diameter at breast height, and volume indexcompared to the middle-aged orchard. On the other hand, even though the control ramets in the middle-aged seed orchard reached a greater height, pruned ramets reached a greater volume index and diameter at breast height. While the height differences observed between control and pruned ramets in all seed orchards at the beginning eventually decreased, it was observed that the heights of pruned ramets grew proportionally larger.
No difference was founded between the control and pruned ramets in terms of cone and conelet production. Pruning intervals and regimes varied in old, middle-aged and young seed orchards, and it was acknowledgedthat top pruning could be used for old, middle-aged and young seed orchard managements.
Salib Yesus – Penderitaan Maria Devosi Maria dalam Ibadat Jalan Salib Versi Solor-Lamaholot
Authors: Kleden Paul Budi
Published: August 2018

Devotion to Mary is one of the most popular religious practices among Catholics, and can be considered one of the oldest forms of popular religiosity. Marian devotions emerged spontaneously as a mixture of elements from local cultures and the Christian faith. However, such practices can become problematic when they overstress certain aspects of human experience together with the role of Mary. This article discusses a text of "The Way of the Cross" which was composed in a dialect of the Lamaholot language as used on the isle of Solor, East Flores.

Kata-kata kunci: devosi, jalan salib, penderitaan, ratapan, harapan
RITUS HODE ILU DALAM MASYARAKAT LEWOINGU: ANTARA TINDAKAN SUPERSTISI DAN REALITAS NUMINUS
Authors: Hayong Bernard Subang
Published: August 2018

The human propensity of openness to the transcendent can be seen as a fundamental predisposition. It is also a need. We encounter such a need in numerous traditions and cultures, including in postmodern societies. In the Hode Ilu ritual, the people of the Lewoingu domain of Eastern Flores (Kabupaten Flores Timur, NTT), express the inseparableness of cosmic reality (humans and their world) with transcendent reality. They experience nature as numinus with supernatural power. This power enables people to submit in awe and act out the heritage of the ancestors in an artistic performance expressing people’s relationship with others, nature, oneself, and with the Divine. This ritual performance is called “artistic” because it is a self expression of the community through ritual that emphasises a fundamental cosmic harmony which is both religious (transcendent) and ethical (in the here and now). When the tradition expresses a form of faith in the transcendent in ritual, then the sharing of human experiences, including relationships of people with the Transcendent, with the cosmos, with others, and with oneself, is not wrong. Also, in such ritual performances, we see a change of perspective and a change in human action regarding oneself, others, nature (with its powers), and with the Divine.
ADORASI SAKRAMEN MAHAKUDUS: HIDUP KARENA DITANTANG
Authors: Ledot Ignasius
Published: August 2018

Sanguis Martyrum Semen Christianorum. The blood of the martyrs is the seed of the church. This well-known expression of Tertulian concerns the growth of the faith in times of great challenge. History notes that devotion to and worship of the Eucharist has long been present in the Western Catholic tradition, and in fact has grown whenever there has been harrassment and challenge. Adoration of the Sacrament is a form of devotion that can help one to experience the presence of God in one’s life and at the same time it can be an expression of deep love of Him who has errected his tent in the midst of his people. Thus, there is a close relationship between the Eucharist and devotion. Nevertheless, it must be remembered that eucharistic devotion must never replace the liturgical celebration of the Eucharist. In the order of ecclesial values, the liturgical celebration of the Eucharist has the first and highest place.

Keywords: Adorasi, liturgi, devosi, gereja, sakramen mahakudus, penghormatan, ekaristi, puncak.
JEN IN CONFUCIUS’S ANALECTS
Authors: Chang William
Published: August 2018

Penulis menjelaskan sentralitas konsep ‘Jen’ dalam filsafat moral Konfusius dan menguraikan sejumlah besar pemahaman konsep ini agar bisa memahami maknanya yang sebenarnya dalam Analects Konfusius. Selanjutnya, konsep ‘Jen’ dibandingkan dengan dengan paham ‘cinta kasih’ dalam Injil Yohanes. Kemudian, penulis mengupas arti ‘Jen’ dalam relasinya dengan konsep ‘Li’ dan konsep ‘Chun-tzu’. Penulis mengambil kesimpulan bahwa ‘Jen’ adalah satu kebijakan universal yang inklusif dan yang dapat mengantar orang kepada kesempurnaan moral. Realisasi Jen, yang berakar dalam cinta, adalah selalu dalam relasi dengan orang lain.

Keywords: Confucius, Moral Philosophy, Jen, Li, Chun-Tzu, love.
System and activity approach to teaching humanities subjects at school: status and prospects
Authors: Logacheva T. N. , Fadeeva L. V.
Published: August 2018

The article examines the problems of approaches to teaching humanitarian subjects at school. We also consider the history of creating a systematic approach to learning and activity. In connection with the social introduction of the new Federal State Educational Standard (GEF), the system-activity approach aimed at the development of the individual, on the formation of a particular identity, philosophically based on the provision of correspondence of the educational activity of students of their age category. The task – the formation of knowledge in accordance with the new standards stands before the teachers. The very system-activity approach is the formation of the educational process, in which an important place is given to active and versatile employment of the student.
Development of the banking sector on the basis of modern technologies of service
Authors: Ermolenko O. M.
Published: August 2018

The article discusses the main technologies of banking services that determine the quality and level of interaction between banks and customers, as well as to determine the level of innovation and attractiveness of the functioning of commercial banks in the market of banking products and services. Each credit institution forms its strategy taking into account its financial capabilities and the level of technology use, so the provision of new and the most attractive innovations allows banks not only to minimize the level of costs, and increase their activity as financial intermediaries. In addition, at the level of increased competition, all banks are not just trying to keep customers, but also to entice them from other banks, which also determines the level of innovation activity of the Bank. All this determines the main vector of development of the banking sector.
Investment projects and development of municipal and regional investment policy
Authors: Bolganova I. V.
Published: August 2018

The article examines the relevant issues related to the investment projects, the creation of investment programs and to carrying out the investment policy on the municipal and regional levels. Any municipality has to solve a lot of problems concerning a decent level of economic and social development of the area and the life standard of their residents. In conditions of the constant shortage of financial resources needed to solve the objectives, the investment policy becomes the major tool. Its main aim is not only to attract extra resources but also to distribute them properly. It requires both some certain legal conditions which allow correct evaluation of the social and economic situation in the municipalities, investment climate, conditions for the investment activities infrastructure development and the properly developed business, investment and corporate culture of the population.

For most of the Russian territories the problem of attracting investments into the real production sector remains urgent. The solution of this problem requires rational approach to the determination and selection of the most appropriate investment directions and the evaluation of the perspective investment projects development – suggestions and activities aimed at the achievement of the particular economic, social, ecological and other objectives requiring capital funds.

The relevance of the examined problem leads to another important issue connected with the training of a highly skilled personnel capable of giving proper evaluation of the political situation in the country, specific features of tax policy, microeconomic indexes of the certain area and other factors essential for the investment activity.
Investment attractiveness of the region (on the example of Krasnodar region)
Authors: Lashko S. I. , Saprykina V. Y.
Published: August 2018

The article describes the main components of the economy of the Krasnodar region, which provide leadership and a high level of competitiveness in the Russian economy. The investment climate of the Krasnodar region is estimated by many experts as quite high, which is confirmed by many authoritative interregional ratings. The analysis of priority sectors of the region’s economy to attract foreign investment, including: agriculture, food and processing industry, wine, health resort and tourist complex, manufacturing industry, information and communication technologies. The assessment of the dynamics of investment activity of the Krasnodar region, identified major investment projects currently being implemented. Analyzing the attraction of foreign investments, it is necessary to touch upon the issue of investment support, which is a multi-level process in the Krasnodar region, which has recently been ordered. Assessing the Krasnodar region as an attractive investment region and one of the leaders in terms of investment, with a very low investment risk, it is necessary to consider the existing problems in the region’s economy and attracting investors. Having studied the emerging problems on the way of investors, the possible directions of further development and improvement of the investment attractiveness of the Krasnodar region.
Comparative psycholinguistic analysis of the communicative styles of the american TV presenters (on the example of tv shows by Oprah Winfrey and Larry King)
Authors: Davydova I. O.
Published: August 2018

This article analyzes the psycholinguistic features of communicative behavior, speech style of two popular American TV hosts: Oprah Winfrey and Larry King. The material for the study was the interview of TV presenters, based on 50 interviews. A person’s personality can be considered as a carrier of a certain culture, an individual fragment or a part of а society, thus, speech behavior of the person, and specifically – the texts produced by him, can and should be searched in national-cultural, socially conditioned and individual components. The research is carried out in the direction of the actual modern science – gender linguistics and reveals the linguistic, psychological and ethnospecific features of the communicative style of American TV hosts. The author develops an interdisciplinary approach to solving problems at the intersection of Humanities: linguistics, psychology, cognitive science, genderology, journalism.

As a result of the linguistic analysis, the author comes to the conclusion that the male style of interviewing Larry King is characterized by restraint, official style, clear structure of the interview; Oprah Winfrey’s speech style is characterized by emotionality, openness, characteristic of the conversational style of communication. However, the revealed gender features of the analyzed interviews do not affect the success of achieving the goals set by the interviewer. The presenter receives information through the use of psycholinguistic techniques. The result was a success regardless of the chosen tactics of negotiating in the analyzed interviews.
Uso de Ciclosporina en Psoriasis: Revisión de la literatura
Authors: Martínez D. María Catalina , Valdés A. María Del Pilar , Valenzuela A. Fernando
Published: August 2018

La ciclosporina (Cs) es un agente sistémico efectivo en psoriasis, que actúa inhibiendo la activación de linfocitos T. Se caracteriza por presentar un rápido inicio de acción, siendo una buena herramienta terapéutica en crisis psoriáticas, como terapia puente a otras terapias de acción más lenta o en pacientes que no han respondido a otros tratamientos. Pulsos cortos de Cs permiten realizar un buen tratamiento con mínima toxicidad en pacientes sin otras comorbilidades. Se han logrado buenos resultados en psoriasis en placa, pustular, eritrodérmica y ungueal. Su uso en psoriasis fue aprobado en 1997 por la FDA.
Caracterización de trabajadores sexuales del área norte de Santiago portadoras de Chlamydia trachomatis
Authors: Pizarro V. Cristián , Pérez C. Fernando , De la Fuente E. Raúl , Santander C. Ester
Published: August 2018

Marco Teórico: Chlamydia trachomatis, agente bacteriano de infección de transmisión sexual (ITS) más frecuente en el mundo, se asocia a patología inflamatoria y neonatal, y a infertilidad. Las trabajadoras sexuales constituyen un grupo de alto riesgo para su contagio.Objetivo: Caracterizar trabajadoras sexuales portadoras de C. trachomatis del área norte de Santiago. Pacientes y Métodos: 36 trabajadoras sexuales con inmunofluorescencia directa positiva para C. trachomatis controladas en una Unidad de ITS. Se analizó en sus fichas clínicas: nivel educacional, uso de alcohol y drogas, tendencia sexual, ITS asociadas y uso de preservativo. Esta información se comparó con fichas clínicas de trabajadoras sexuales no portadoras. Resultados: No se encontraron diferencias estadísticamente significativas entre portadoras y no portadoras, a partir de la revisión de registros clínicos.Conclusión: El diagnóstico de infección de C. trachomatis y su adecuado control requieren de procedimientos estandarizados para su implementación en grupos de alto riesgo.
Demodicosis: Revisión de la literatura
Authors: Andreani Juan , Pérez Fernando , Molina María Teresa , De la Fuente Raúl
Published: August 2018

La demodicosis es una patología cutánea crónica caracteriza-da por lesiones eritemato-maculares pruriginosas, cuyo agente causal son ácaros foliculares del género Demodex. Presenta un abanico amplio y polimorfo de manifestaciones clínicas, donde la sospecha clínica se presentará frente a una erupción facial crónica persistente o recurrente, resistente a terapia conven-cional y de distribución asimétrica. El diagnóstico definitio es difícil, y requiere un cuadro clínico compatible y la presencia de alta densidad de Demodex.El siguiente documento hace una revisión de conceptos con respecto a la patogenia, clínica, diagnóstico y tratamiento de esta entidad.
Xantogranuloma juvenil múltiple: Variante inusual en un lactante
Authors: Pineda Sebastián , Le-Bert Marcela , Aspée Mauricio
Published: August 2018

El Xantogranuloma Juvenil (XJ) es un tumor benigno de la in-fancia, constituido por histiocitos progresivamente lipidizados, en ausencia de anomalías metabólicas.Se reporta un caso de XJ múltiple en un lactante.Paciente masculino de 1 año y 11 meses de edad, sin antece-dentes mórbidos. Consultó por lesiones de 15 meses de evo-lución en cuero cabelludo. Al examen físico destacaban dos pápulas amarillentas y tres máculas anaranjadas en cuero ca-belludo. A la dermatoscopía se apreciaba un color amarillo-naranja homogéneo. La biopsia incisional demostró infiltradode histiocitos en dermis y células de Touton. A la inmunohis-toquímica, los histiocitos fueron CD68 positivo, S100 negativo y CD1a negativo. Los exámenes de laboratorio y la evaluación por oftalmología no evidenciaron anormalidades.El XJ es un tumor benigno, siendo la forma más común de Histiocitosis no Langerhans. El 90% de las veces ocurre en etapas tempranas de la vida. Se caracteriza por una pápula o nódulo asintomático, amarillo-anaranjado, que compromete cabeza, cuello y/o tronco superior. Hasta el 82% de los casos se manifiestade manera única. El ojo es el sitio extracutáneo más frecuentemente comprometido. La dermatoscopía descri-be un patrón de “puesta de sol”. Su pronóstico es bueno y tien-de a involucionar a los 3-6 años desde su aparición.Se presenta este caso dado que el XJ múltiple es menos fre-cuente de observar que su forma única y para recordar que su asociación con neurofibomatosis tipo 1 predispone a un mayor riesgo de desarrollar una leucemia mieloide crónica in-fantil.
Hidradenitis supurativa: Dramática respuesta a metformina en una paciente sin resistencia a la insulina
Authors: Niklitschek Sergio , Vial Verónica , Traipe María Paz , Kinzel Francisca , Ramírez Cristian , Kolbach Marianne
Published: August 2018

La Hidradenitis Supurativa (HS) es una enfermedad inflam-toria crónica de la piel, en la que se han utilizado múltiples tra-tamientos, con respuesta variable. Se presenta el caso de una paciente con HS sin resistencia a la insulina, que fue tratada satisfactoriamente utilizando metformina oral.Paciente mujer de 22 años, consultó por HS de cuatro años de evolución. Presentaba sobrepeso, pero no resistencia a la insu-lina ni síndrome de ovario poliquístico. Durante los primeros seis meses de tratamiento recibió antibióticos orales, antibióti-cos tópicos, cloruro de aluminio tópico y corticosteroides intra-lesionales, con escasa respuesta. Después de estos tratamientos, se le indicó metformina y luego de doce días de tratamiento todas las lesiones inflamtorias remitieron. Un año después, no ha presentado nuevas lesiones. La metformina podría ser una excelente opción de tratamien-to para los pacientes con HS no necesariamente asociada con resistencia a la insulina
Epidermodisplasia Verruciforme
Authors: Alarcón Rosario , Santana Daniela , Constanzo Claudia , Contreras Loreto
Published: August 2018

La epidermodisplasia verruciforme (EV) es una genoderma-tosis rara, caracterizada por el desarrollo de verrugas planas y lesiones similares a pitiriasis versicolor, asociada a infección crónica por Virus Papiloma Humano. Se reporta el caso de EV. Mujer de 49 años con múltiples lesiones verrucosas de larga evolución distribuidas en las cuatro extremidades y an-tecedente familiar de cuadro similar. Biopsia a los 19 años evi-denció verrugas sin atipia. Nuevo estudio histológico informó carcinoma escamoso, decidiéndose extirpación de lesiones. La clínica inicia en edades tempranas, con elevado riesgo de transformación maligna. No existe tratamiento específic. Es esencial la fotoprotección estricta y manejo precoz de lesiones para prevención de progresión a carcinoma.
Síndrome de Nevo Becker con características ictiosiformes
Authors: Maira María Elsa , Gálvez Karla , Martínez María Catalina , Wortsman Ximena , Carreño Laura
Published: August 2018

El nevo de Becker, es un hamartoma cutáneo benigno de etiología desconocida, que se presenta como una mácula hiperpigmentada de bordes geográficos. Por lo general se ubica en la región torácica superior y su compromiso tiende a ser unilateral. Ocasionalmente el nevo de Becker se asocia a anomalías en el tejido óseo, muscular o cutáneo, siendo la ictiosis una característica muy infrecuente.  La presencia de alguna de estas anomalías asociadas a un nevo de Becker determina el síndrome del nevo de Becker. Paciente de sexo masculino de 18 años, que consultó por un cuadro iniciado en la infancia, caracterizado por la aparición de manchas cafés, escamosas, pruriginosas que inicialmente se ubicaron en las extremidades inferiores y con el tiempo fueron apareciendo en tronco, región lumbar y glútea. Mediante la correlación clínico-patológica se llegó al diagnóstico de nevo de Becker, con características ictiosiformes. Se realizó estudios complementarios con ecocardiograma Doppler y radiografía de tórax, que resultaron  normales y una ecotomografía Doppler color de tórax anterior   que mostró  una  leve ginecomastia bilateral con discreto aumento del botón mamario derecho y una leve  hipoplasia del pectoral mayor derecho diagnosticándose Síndrome de nevo de Becker. La mayoría de los reportes de Síndrome de nevo de Becker describen anomalías como escoliosis o hipoplasia unilateral de la mama, con escasos reportes sobre ictiosis. Se reporta este caso por su presentación atípica con múltiples nevos de Becker, compromiso de hemicuerpo inferior y  su asociación ictiosiforme poco descrita en la literatura.
Enfermedad de Hailey-Hailey: reporte de casos entre los años 2001 y 2016 en un hospital universitario y revisión de la literatura
Authors: Chaparro Ximena , Kaplan Viera , Pulgar Constanza , Saavedra Tirsa , Morales Claudia , Carreño Laura
Published: August 2018

Introducción: La enfermedad de Hailey-Hailey (pénfigo crónico familiar benigno) es una dermatosis ampollar, de evolución crónica, recidivante, autosómica dominante, de penetrancia y expresividad variables, localizada predominantemente en los pliegues.Métodos: Se realizó una revisión de la base de datos del Servicio Anatomía Patológica del Hospital Clínico Universidad de Chile (HCUCH) entre los años 2001 y 2016 y se complementaron con los antecedentes clínicos extraídos de las fichas clínicas.Resultados: Se obtuvo un total de 6 casos ilustrativos de la patología en estudio.Discusión y conclusiones: La enfermedad de Hailey-Hailey es una genodermatosis poco frecuente cuyo diagnóstico y tratamiento constituyen un desafío para el dermatólogo.
Guías clínicas chilenas para el manejo de la psoriasis
Authors: Valenzuela Fernando , Araya Irene , Correa Hernán , De la Cruz Claudia , Riveros Tatiana , Valdés María Pilar
Published: August 2018

Esta guía clínica ha sido desarrollada para orientar al médico en el enfrentamiento global, seguimiento y tratamiento del paciente psoriático en las diversas formas de la enfermedad. La psoriasis es una enfermedad de presentación variable, tratada tradicionalmente con múltiples terapias con resultados positivos, pero sin que los tratamientos hayan sido sometidos a las evaluaciones y seguimientos que se exigen hoy en día. Tampoco existe literatura de la eficacia comparativa de terapias orales tradicionales versus fototerapia. Si existe literatura que avala la eficacia de tratamientos de reciente desarrollo cuyos resultados son sometidos a estándares estrictos. Además, está claramente documentado que existe una diferencia entre el “tratamiento ideal indicado” y el “tratamiento que el paciente realiza”, siendo la adherencia al tratamiento y las preferencias del paciente respecto de la modalidad terapéutica a utilizar un factor importante a tomar en cuenta. Por lo tanto, en estas guías se han incorporado las terapias tradicionales, más las terapias con respaldo basado en evidencia científica y tratando de respetar las preferencias de los pacientes.
Queratosis Pilar simil asociado a uso de Nilotinib
Authors: Ramírez Constanza , González Sebastián , Cuevas Sussan
Published: August 2018

Nilotinib es un inhibidor altamente selectivo de BCR-ABL tirosina kinasa usado para el tratamiento de Leucemia mieloide crónica. Las reacciones cutáneas fueron uno de los efectos adversos no hematológicos más frecuentemente reportados en relación al uso de esta droga.El presente artículo documenta el caso una paciente femenina de 17 años de edad diagnosticada con Leucemia mieloide crónica que había estado en tratamiento con Nilotinib por 5 meses desarrollando una reacción tipo queratosis pilar. La paciente fue tratada con medidas generales, Urea 15% y antihistamínicos, con cese del prurito.Es importante reconocer las reacciones cutáneas asociadas al uso de Nilotinib para así otorgar alivio oportuno de los síntomas con el fin de lograr una mejor adherencia al   tratamiento de la Leucemia mieloide crónica y mejorar la calidad de vida del paciente.
Manejo despigmentante de vitiligo generalizado con monobenzil eter de hidroquinona
Authors: Charlín Raúl , Valenzuela Karen
Published: August 2018

El vitiligo es una patología crónica, recidivante y difícil de tratar. El objetivo primario del tratamiento es inducir la repigmentación, sin embargo en casos extensos refractarios a tratamiento, se puede realizar despigmentación para corregir la discromía. Dentro de los tratamientos despigmentantes en vitiligo, a la fecha el único aprobado por la FDA es el Monobenzil éter de hidroquinona (monobenzona). Se expone el caso de una paciente con vitiligo extenso y refractario a tratamiento que fue manejado con monobenzona. El resultado fue exitoso durante tiempo prolongado, con recaída parcial al suspender el medicamento. La recaída remitió con el reinicio de la monobenzona. Sin nueva recaída actualmente con tratamiento de mantención 3v/semana. La monobenzona induce acromía secundaria a necrosis de los melanocitos. Se requiere su uso 1 a 2 veces al día por 6-12 meses para lograr la despigmentación. En pacientes adecuadamente seleccionados, es una alternativa válida para el manejo del vitiligo. Se presenta un caso exitoso de despigmentación con monobenzona. Actualmente, la paciente está muy satisfecha con los resultados.
Úlceras por hidroxiurea en paciente con policitemia vera
Authors: Álvarez Danae , Arellano Javier , Silva Catalina , Corredoira Yamile
Published: August 2018

La hidroxiurea es un agente citostático que inhibe la síntesis de ADN. Se considera el tratamiento de primera línea para algunos trastornos mieloproliferativos, enfermedad de células falciformes, casos severos de psoriasis refractaria y como adyuvante en la terapia de VIH. Se ha informado de que algunos pacientes tratados con hidroxiurea pueden tener úlceras en las extremidades inferiores. Paciente femenino de 67 años de edad con antecedentes de policitemia vera tratada con hidroxiurea durante un año, se deriva a dermatología por presentar úlceras bilaterales en extremidades inferiores. Al examen físico se evidencian dos lesiones ulceradas en la región calcánea. Se realiza una biopsia de piel, y muestra signos no específicos de inflamación. Se decide la interrupción de la hidroxiurea y se inicia la terapia adyuvante con pentoxifilina. Las lesiones se resolvieron en dos meses, dejando una pequeña cicatriz residual. Es importante recordar esta rara complicación inducida por el uso prolongado de la hidroxiurea y, de esta manera, realizar un diagnóstico precoz y tratamiento adecuado, que hasta el momento es básicamente la suspensión de la hidroxiurea.
Pseudocola humana: Reporte de caso
Authors: Hott Karla , Villagra Mauricio , Aranibar Ligia , Morales Claudia
Published: August 2018

Una pseudocola se define como una lesión con forma de cola en la región lumbosacrococcigea que no es una cola real, sino que, por el contrario, es causada por alguna enfermedad subyacente.  El lipoma perineal es una de las condiciones que puede presentarse como una pseudocola.  El lipoma perineal congénito es una enfermedad rara, pero un lipoma perineal congénito sin otras anomalías es, en particular, extremadamente raro.Reportamos un caso de un lipoma perineal congénito aislado, sin malformaciones asociadas, que se presenta como una pseudocola y además incluimos una revisión bibliográfica de la condición.
Manejo médico de la hiperhidrosis
Authors: Lorca María Bernardita , Bruning Carmen , Giordano María Consuelo , Amat Pedro , Alonso Traviesa Faustino Tomás
Published: August 2018

La hiperhidrosis es un aumento patológico de la sudoración, que puede asociarse a patologías médicas y fármacos, afectando en forma significativa la calidad de vida. La hiperhidrosis focal primaria es una patología común, cuyo manejo es un desafío. Están disponibles múltiples terapias para el tratamiento de hiperhidrosis, incluyendo productos tópicos, iontoforesis, toxina botulínica, fármacos sistémicos, cirugía y nuevos equipos para destrucción selectiva de las glándulas sudoríparas. El propósito de este artículo es revisar la literatura, enfocándose en las terapias no quirúrgicas y opciones de tratamiento emergentes.
Tuberculosis cutánea
Authors: Llancapi Patricio , Delgado Carolina , Mendoza Francisco , Santana Daniela , Constanzo Claudia
Published: August 2018

La tuberculosis cutánea (TC) es una afección infrecuente dentro de la tuberculosis extrapulmonar, siendo su clínica variada e inespecífica. Se presenta el caso de TC: Mujer de 48 años sin antecedentes mórbidos que consultó por lesión cutánea en pabellón auricular y piel circundante, de dos años de evolución, pruriginosa, con aumento de tamaño progresivo y supuración serosa ocasional, al examen se constató placa eritematosa anaranjada, de consistencia blanda. Reacción en Cadena de Polimerasa de biopsia evidenció infección por Mycobacterium tuberculosis, logrando remisión de la lesión con tratamiento antituberculoso establecido en las normas sanitarias de Chile. La TC es una entidad de difícil diagnóstico, incluso contando con cultivos. A causa del aumento de casos de tuberculosis por el incremento de factores inmunosupresores, y a su potencial agresividad sistémica, se recomienda un alto nivel de sospecha.
Reacción Lepromatosa Tipo I: A propósito de un caso
Authors: Uriarte Diego , Gomez Bertha , Salazar Francisco , Rodríguez Marco , Hernández María de las Mercedes
Published: August 2018

Paciente masculino 59 años que acude a consulta con resultado de biopsia de piel con diagnóstico de enfermedad de Hansen y antecedente de cónyuge con previo diagnóstico de Lepra lepromatosa, se inicia tratamiento con poliquimioterapia supervisada, con buena respuesta al mismo, y nueve meses posteriores comienza con manchas en piel pruriginosas, disestesias, parestesias en tronco y extremidades, acompañado de sudoraciones nocturnas. A la exploración física presenta dermatosis que afecta tronco, en ambas caras y extremidades superiores; constituida por múltiples placas eritematosas infiltradas, con borde externo elevado activo, interno diseminado que van de 1 a 5 cm de diámetro, de aspecto irregular, evolución aparente crónica. Al examen neurológico se observa pannus lepromatoso en ojo derecho, prueba de pica y toca con alteración de la sensibilidad en tronco. Se sospecha de reacción lepromatosa tipo I, iniciando tratamiento con prednisona. Se solicitó estudio histopatológico donde se observó células gigantes, acompañado de edema dérmico y dentro del granuloma.
Osteoartropatía hipertrófica primaria y queratodermia palmoplantar: a propósito de un caso
Authors: Maturana Escobar Juan Ignacio , Fuentes Finkelstein Paulina , Guglielmetti Valenzuela Antonio
Published: August 2018

La acropaquia es un trastorno que puede presentarse en forma aislada o formar parte del síndrome de osteoartropatía hipertrófica, entidad caracterizada por periostosis, dolor articular y acropaquia.Cuando este síndrome es causado por una mutación genética específica, se denomina osteoartropatía hipertrófica primaria.Este raro desorden hereditario se asocia además a alteraciones dermatológicas típicas, como hiperseborrea, acné, engrosamiento de pliegues faciales, entre otras. Una asociación rara vez descrita es la queratodermia palmoplantar.Se presentará el caso de una mujer de 46 años con osteoartropatía hipertrófica primaria asociada a queratodermia palmoplantar que asistió a la unidad de dermatología del Hospital Gustavo Fricke, Viña del Mar, Chile.
Implementasi Asas-Asas Umum Pemerintahan Yang Baik di Lingkungan Peradilan Administrasi Negara
Authors: Syuhudi Ichsan
Published: August 2018

Secara teknis operasional, bahwa proses yang ditempuh oleh hukum administrasi negara pada saat menerapkan asas-asas umum pemerintahan yang layak sebagai alat uji terhadap keputusan administrasi negara mempunyai beberapa unsur kesamaan dengan proses penerapan hukum di pengadilan perdata. Dalam penerapan asas-asas umum pemerintahan yang layak sebagai alat uji terhadap keabsahan keputusan administrasi negara dapat didekati dengan tiga sudut pandang untuk membahasnya yaitu historis, teoritis dan yuridis praktis
Kata Kunci:    Asas-asas Umum Pemerintahan Yang baik, Peradilan Administrasi, Freies Ermessen, Bestuurzorg
Penggunaan Komunikasi Bluetooth Pada Smartphone Android Untuk Pengiriman Data Pada Jam Digital Berbasis Arduino
Authors: Sarifudin Sarifudin , Manshur Manshur , Tirtana Angga
Published: August 2018

The schedule of prayer is very important akan ada.Masa Today many in the mosque as well as in homes that usually have a calendar and the viewer time of eternal prayer, but it looks so small that it can not be seen from a great distance. This prayer timepiece uses a display display dot matrix P4, displaying the date, digital clock as well as the 5th time of the prayer. So that prayer times can be changed in real time according to time and day changes, and can be seen from a great distance and can be used to maximize the time available. This research produces a digital clock time system that uses dot-matrix as display, RTC as real time clock, bluetooth as sender of data from smart mobile device android, and buzzer as alarm. So that the system formed the digital clock time of this prayer. Based on design, implementation and testing, the arduino-based digital time-shaped design tool can be used for digital clocks and bookmarks and prayer time reminders.