bluuebunny/crossref_metadata_2025 huggingface dataset:
“The Inspired Child of [Her] Times”
Authors: Pitavy-Souques Danièle
Published: January 2023

This chapter reviews twentieth-century revolutions in aesthetics, science, and politics as witnessed by Eudora Welty and that are evident in her work: cubism, expressionism, surrealism, abstraction, futurism, psychology, fascism, totalitarianism, world wars, and poverty. With dozens of Welty’s fictions, nonfictions, and photographs including “Powerhouse,” “Kin,” Delta Wedding, The Ponder Heart, and “The Demonstrators,” the chapter describes Welty’s narrative techniques of displacement and transformation and her expression of two philosophies of art: emotion and vision. Picasso, Kandinsky, Freud, Cocteau, Buñuel, and Pollack are among the twentieth-century figures who resisted representation in favor of experimentation, new concepts, and techniques by which Welty created her art.
“Moments of Truth”
Authors: Pitavy-Souques Danièle
Published: January 2023

This chapter focuses on Eudora Welty’s Losing Battles, The Optimist’s Daughter, and One Writer’s Beginnings to address the critical question of the future for literature by analyzing Barthes’ “moments of truth” in Welty’s late novels and autobiography. These long form texts, written between the late 1960s and 1984, demonstrate a marked shift in Welty’s point of view and techniques of form, a departure from the short story, to comprise a “new” period of her work in which the power of emotion and growing relationships are developed through the “interplay of memories, digressions, echoes, and uncertainty.” The “moments of truth” in the long form works of the renowned author prove the value of literature to transmit a probing investigation of the human spirit’s universal drive to commemorate, commiserate, and to thrive.
Everyday Ephemeral Content
Authors: Barker Cory
Published: January 2023

The conclusion considers directives by Twitter and Facebook to distribute original video content. These announcements again crystallize how television—and television industry strategies—are continuously remediated into newer platforms. They also point to a logical maturation of Social TV. Rather than serve as mediators between the industry and the audience, and between multiple screens, Facebook and Twitter have sought to unify the Social TV experience into one space and on one screen. In this regard, there is a flattening of television programming, social chatter, memes, and sponsored posts into an incessant stream of content. Social TV lives on through this deluge of ephemera, giving media brands even more prominence within the multi-platform ecosystem.
IMPLEMENTASI MOBILE FORENSIC PADA APLIKASI MICHAT DAN TELEGRAM DENGAN FRAMEWORK NIST 800-101
Authors: Maniar Nadia Ayu Isroh , Yuniati Trihastuti
Published: January 2023

Sosial media adalah sebuah media untuk bersosialisasi satu sama lain yang dilakukan secara online untuk memudahkan manusia saling berinteraksi tanpa batas ruang dan waktu. Salah satu aplikasi yang kini banyak disalahgunakan yaitu aplikasi MiChat dan Telegram, banyak kasus prostitusi online yang ditemukan menggunakan aplikasi ini lantaran mudah diakses karena dapat kirim foto dan video. Barang bukti kejahatan cybercrime dapat berupa barang bukti elektronik dan barang bukti digital. Barang bukti elektronik dapat berupa bentuk fisik dari perangkat elektronik tersebut sedangkan barang bukti digital bisa berupa berkas dokumen, berkas history, atau berkas log yang berisi data-data yang terkait. Penelitian ini menerapkan forensik digital pada perangkat mobile menggunakan framework National Institute of Standards and Technology Special Publication 800-101 Revision 1, dengan alat bantu forensik yaitu FTK Imager dan MOBILedit Forensic. Hasil penelitian menunjukkan bahwa FTK Imager lebih banyak mendapatkan barang bukti digital dibandingkan MOBILedit Forensic. Akuisisi bukti digital pada aplikasi Telegram mendapatkan lebih sedikit bukti dibandingkan dengan aplikasi MiChat. Bukti digital yang berhasil didapatkan pada penelitian ini yaitu pesan percakapan, gambar, video dan voice note.
Kata kunci: cybercrime, digital forensik, michat, nist, telegram
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Social media is a platform for online communication that allows people to interact without being limited by space and time. One of the commonly used applications for criminal activities such as online prostitution is MiChat and Telegram, because these applications are easily accessible and allow users to send photos and videos. Cybercrime evidence can be in the form of electronic and digital evidence. Electronic evidence is the physical form of electronic devices involved in a crime, while digital evidence is documents, history, or logs containing data related to the crime. This study examines the implementation of forensic techniques on mobile devices using the MiChat and Telegram applications. The aim is to collect and analyze data that can be used as evidence in an investigation. This study uses the framework of the National Institute of Standards and Technology Special Publication 800-101 Revision 1 and uses FTK Imager and MOBILedit Forensic as assistance tools. The results show that FTK Imager obtained more digital evidence compared to MOBILedit Forensic, and the acquisition of digital evidence on the Telegram application obtained fewer evidences compared to the MiChat application. The successfully obtained digital evidence includes conversation messages, images, videos, and voice notes.
Keywords: cybercrime, digital forensik, michat, nist, telegram
Investigation of factors underlying foreign language classroom anxiety in Chinese university English majors
Authors: Zhang Shuting , Lai Chun
Published: January 2023

Previous research on foreign language classroom anxiety (FLCA) has reported inconsistent findings. One significant reason is that these studies mainly adopted a data-driven approach and lacked a strong theoretical basis. This study thus examined the factors underlying FLCA with worry-emotionality theorization of anxiety (Liebert, Robert M. & Larry W. Morris. 1967. Cognitive and emotional components of test anxiety: A distinction and some initial data. Psychological Reports 20. 975–978). A preliminary survey was conducted to validate the original FLCAS with 603 English majors from two Chinese universities, and 20 of them were invited for individual interviews to better understand the factors contributing to their FLCA. Based on these, a questionnaire was constructed through adapting the Foreign Language Classroom Anxiety Scale (FLCAS) and used in a main survey among 557 Chinese university English majors. Exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were performed to analyse the survey data, while thematic analysis was used to analyse the interview data. In addition to three factors reported in the FLCA factor validation literature, communication apprehension, self-confidence in speaking English and fear of negative evaluation, this study identified peer pressure as a new factor. The findings reveal the multidimensional nature of FLCA and support the worry-emotionality theorization of anxiety. Implications for the conceptualization of FLCA are discussed.
Tutorial: statistical methods for the meta-analysis of diagnostic test accuracy studies
Authors: Schlattmann Peter
Published: January 2023

This tutorial shows how to perform a meta-analysis of diagnostic test accuracy studies (DTA) based on a 2 × 2 table available for each included primary study. First, univariate methods for meta-analysis of sensitivity and specificity are presented. Then the use of univariate logistic regression models with and without random effects for e.g. sensitivity is described. Diagnostic odds ratios (DOR) are then introduced to combine sensitivity and specificity into one single measure and to assess publication bias. Finally, bivariate random effects models using the exact binomial likelihood to describe within-study variability and a normal distribution to describe between-study variability are presented as the method of choice. Based on this model summary receiver operating characteristic (sROC) curves are constructed using a regression model logit-true positive rate (TPR) over logit-false positive rate (FPR). Also it is demonstrated how to perform the necessary calculations with the freely available software R. As an example a meta-analysis of DTA studies using Procalcitonin as a diagnostic marker for sepsis is presented.
Indirectly determined reference intervals for automated white blood cell differentials of pediatric patients in Berlin and Brandenburg
Authors: Mrosewski Ingo , Dähn Tobias , Hehde Jörg , Kalinowski Elena , Lindner Ilona , Meyer Thea Maria , Olschinsky-Szermer Michael , Pahl Jana , Puls Monika , Sachse Kristin , Switkowski Rafael
Published: January 2023

Objectives

Establishing direct reference intervals for pediatric patients is a costly, challenging, and time-consuming enterprise. Indirectly established reference intervals can help to ameliorate this situation. It was our objective to establish population-specific reference intervals for automated white blood cell differentials via data mining and non-parametric percentile method.

Methods

Blood counts and automated white blood cell differentials of patients aged 0 days to 18 years, performed from the 1st of January 2018 until the 30th of June 2022, were identified in our laboratory information system. Reference intervals were established in accordance with IFCC and CLSI recommendations as well as the propositions by Haeckel et al.

Results

Initially, 47,173 blood counts on our SYSMEX XN-9000 were identified. 11,707 data sets were excluded, leaving 35,466 sample sets for analysis. Of these, 17,616 contained automated white blood cell differentials. Due to insufficient patient numbers, no reference intervals for automated white blood cell differentials could be established for children aged <7 months. In comparison to the corresponding reference intervals published by Herklotz et al., reference intervals determined by us showed relevant differences throughout all age groups.

Conclusions

The combination of non-parametric percentile method and the propositions by Haeckel et al. utilizing conscientious data mining appears to be potent alternative to direct reference interval determination.
Waste aggregate concrete properties using waste tiles as coarse aggregate and modified with PC superplasticizer
Authors: Al-Labban Salama Nasim Yousif , Abdullah Firas Abdulhadi , Karagoly Yahya Hamza , Shubber Mustafa Salman , Hasan Suhad Abdulsattar , Jabal Qusay A.
Published: January 2023

Concrete is the most popular construction material and has a relatively high compressive strength and it does not crack under its own weight, but its tensile strength is much lower compared to its compressive strength. The compressive strength can be changed according to the water to cement ratio during concrete formation or mixing, while the tensile strength rises when additives are used, concrete needs reinforcing steel, and added to plain concrete, resulting in reinforced concrete. In other terms, concrete consists of sand or fine aggregate, gravel (which is a coarse aggregate), water, and cement (which is considered a bonding material), and it is a brittle material that needs reinforcement and also some admixtures to improve its low tensile resist. This research aims to increase and improve some mechanical properties of concrete by using waste tiles as coarse aggregate. The study includes replacing normal aggregates with waste tile and using them as crushed aggregate with 25, 50, 75, and 100% replacement. Studies show increment in compressive and tensile strength and flexural strength by using waste tile aggregate compared with ordinary concrete; compressive strength increased from 34.1 MPa for reference mixes without waste tiles to 39.8 MPa using waste tiles. The study included improving all mixes with polycarboxylate superplasticizer and gaining high strength concrete, especially mixes with 50, 75, and 100% waste tile aggregate; the compressive strength with totally waste tile replacement gave the highest value of compressive strength, which was 57.5 MPa, tensile and flexural strength also increased by using waste tile aggregate, and 100% replacement shows optimum values of mechanical properties in this study.
A leader or a comedian? Perceptions of politicians based on their use of humor on Twitter
Authors: Mendiburo-Seguel Andrés , Buie Hannah , Alenda Stéphanie , Navia Patricio
Published: January 2023

Politicians are tasked with both holding expertise and being relatable to the general population they are representing. Accordingly, politicians strategize their communication style to achieve both aims. One strategy they implement is using humor in their communication to constituents. But is this an effective strategy across humor styles? Does political affiliation or gender of the politician impact these effects? We examine these questions in an online experiment with Chilean subjects (N = 799) using tweets from fictitious politicians, finding evidence that both serious and humorous aggressive communication had negative outcomes on social perception of the politician compared to affiliative and self-deprecating communication. Both serious and humorous affiliative communication has a positive outcome on social perceptions compared to aggressive and most self-deprecating communications. Also, self-deprecating humor was a moderately effective communication strategy, and political affiliation did not have an effect on perceptions of likability when affiliative humor was used. Finally, we did not find evidence of differences in social perceptions based on the gender of the politician.
Performance enhancement of duobinary modulation-based DWDM system using particle swarm optimization
Authors: Singh Kuldeep , Arya Sandeep K. , Kumar Vinod
Published: January 2023

The next-generation light wave communication DWDM networks can accommodate large number of channels to efficiently utilize the bandwidth (BW). However, in the deployment of DWDM system mixing of two or more waves limits the performance due to four wave mixing (FWM) nonlinearity in fiber. This article, presents improved performance analysis of DWDM using a proposed improved duobinary modulation (IDBM), modified duobinary modulation (MDBM) and duobinary modulation (DBM) model for mitigation of FWM nonlinearities has been estimated experimentally through interference of noise on optical signal, FWM efficiency, FWM power etc. In IDBM, a unit delay in addition to time delay parameter is also utilized for generation of electrical duobinary pulses. The parameters of both delay blocks are tuned through particle swarm optimization (PSO) technique to improve the performance. The overall proposed IDBM effectively decreases the FWM. The results obtained for IDBM in terms of Q-factor 8.9, OSNR 18 dB, FWM power −87 dBm and FWM efficiency −70 dB shows substantial improvement with the recommended IDBM technique in comparison to DBM and MDBM schemes.
Tunable replica symmetry breaking in random laser
Authors: Xia Jiangying , Zhang Xiaojuan , Zhou Kaiming , Zhang Lin , Wang Erlei , Du Wenyu , Ma Jiajun , Li Siqi , Xie Kang , Yu Benli , Zhang Junxi , Hu Zhijia
Published: January 2023

Replica symmetry breaking (RSB) has been widely recognized as a statistical analysis approach to understand the disorder and nonlinear interactions in complex systems ranging from atoms to the cosmic scale. However, it is challenging to analyze the nonlinear optical characteristics of random laser (RL) in disordered gain medium via RSB due to the lack of a general RSB-based statistical analysis framework. In this work, we report the tunable RSB in polymer fiber RL, where the effects of temperature and different structures on RSB are investigated experimentally and theoretically. It experimentally proves that RSB in RL is not robust, and disorder and temperature are responsible for tunable RSB in RL, which contributes to the improvement of the statistical analysis framework for investigating the optical principles of RL using RSB. And the finding of the tunable RSB allows to investigate the dynamical differences for various RL systems, which broadens the directions for the use of spin-glass theory to explore the physical mechanism of RL.
Analytical chemistry of engineered nanomaterials: Part 1. Scope, regulation, legislation, and metrology (IUPAC Technical Report)
Authors: Labuda Jan , Barek Jiří , Gajdosechova Zuzana , Goenaga-Infante Heidi , Johnston Linda J. , Mester Zoltan , Shtykov Sergei
Published: January 2023

Analytical chemistry is crucial for understanding the complex behavior observed for engineered nanomaterials (ENMs). A variety of analytical chemistry techniques and methodological approaches are used for isolation/purification and determination of the composition of pristine nanomaterials and for the detection, identification, and quantification of nanomaterials in nano-enabled consumer products and the complex matrices found in cosmetics, food, and environmental and biological samples. Adequate characterization of ENMs also requires physicochemical characterization of number of other properties, including size, shape, and structure. The requirement for assessment of a number of ENM properties frequently requires interdisciplinary approaches and multi-modal analysis methods. This technical report starts with an overview of ENMs definitions and classification, their properties, and analytical scenarios encountered with the analysis of both pristine nanomaterials and complex matrices containing different nanomaterials. An evaluation of the current status regarding nanomaterial identification and characterization for regulatory purposes and legislation, including emerging regulations and related scientific opinions, is provided. The technical report also presents a large and critical overview of the metrology of nanomaterials, including available reference materials and the development and validation of standardized methods that are currently available to address characterization and analysis challenges. The report focuses mainly on chemical analysis techniques and thus it is complementary to previous IUPAC technical reports focused on characterizing the physical parameters of ENMs and on nanotoxicology.
Which ROMs Lead to Rome? A Systematic Review of the Effects of Range of Motion on Muscle Hypertrophy
Authors: Kassiano Witalo , Costa Bruna , Nunes João Pedro , Ribeiro Alex S. , Schoenfeld Brad J. , Cyrino Edilson S.
Published: January 2023

Kassiano, W, Costa, B, Nunes, JP, Ribeiro, AS, Schoenfeld, BJ, and Cyrino, ES. Which ROMs lead to Rome? a systematic review of the effects of range of motion on muscle hypertrophy. J Strength Cond Res XX(X): 000–000, 2022—Resistance exercise range of motion (ROM) influences muscular adaptations. However, there are no consistent practical guidelines about the optimal ROM for maximizing muscle hypertrophy. The objective of this article was to systematically review the literature for studies that compared the effects of full ROM (fROM) and partial ROM (pROM) on muscle hypertrophy. PubMed/MEDLINE, Scopus, and Web of Science databases were searched to identify articles from the earliest record up to and including April 2022. We calculated the effect size (ES) scores of the variables of interest. Eleven studies were included in the review. Full ROM and pROM performed in the initial part of the ROM elicited greater muscle hypertrophy of the rectus femoris, vastus lateralis, biceps brachii, and brachialis distal sites (between-groups ES: 0.20–0.90) than pROM performed in the final part of the ROM. fROM elicited greater muscle growth on the gluteus maximus and adductors than pROM in the final part of the ROM (between-groups ES: 0.24–0.25). Initial pROM produced more favorable proximal rectus femoris hypertrophy than fROM (between-groups ES: 0.35–0.38). pROM in the middle part of the ROM elicited greater triceps brachii hypertrophy than fROM (between-group ES: 1.21). In conclusion, evidence suggests that when training at a longer muscle length—through either pROM or fROM—some muscles, such as quadriceps femoris, biceps brachii, and triceps brachii, tend to experience optimal growth. Thus, the use pROM in the initial part of the excursion in combination with fROM training should be considered when prescribing hypertrophy-oriented resistance training programs.
How to Cancel Plans With Friends: A Mixed Methods Study of Strategy and Experience
Authors: Caron Sophia , Thomas Jacqueline , Torres Alaina , Oh Jeewon , Chopik William
Published: January 2023

Being cancelled on is inevitable. However, maintaining friendships is important and cancelled plans may evoke feelings of disappointment. To prevent this, we examined ways to go about cancelling plans that would not negatively impact friendships. Our study examined what people consider appropriate and inappropriate reasons and the best methods to cancel plans. A variety of close-ended and open-ended questions regarding what participants believed was a reasonable excuse for cancelling and the worst excuse for cancelling was asked. Participants were also asked about how cancelled plans made them feel. Among 1,192 people (72.5% women; 71.8% White), the majority of the participants wanted advanced notice and/or a quick call/text when plans are being cancelled. Health or family reasons were among the most reasonable excuses. Conversely, excuses regarding a better offer, such as finding something better to do, were among the most unacceptable reasons to cancel plans. Over 80% of the sample reported feeling annoyed when they found out that an excuse to cancel was a lie. Honoring commitments is essential to maintaining friendships, which is associated with better health and well-being. When breaking commitments, the best way to go about it is to cancel in advance and have honest and reasonable excuses which serve to maintain friendships that are a fundamental part of life and satisfy the need to belong.
Nutritional Status Related to Work Fatigue in Police Officers at the Traffic Police Directorate of East Java
Authors: Antika Karinda Kennia , Pramono Adriyan
Published: January 2023

Work fatigue can cause a decrease in performance which can lead to work accidents. Fatigue can be caused by several factors including nutritional status and work environment. This study aimed to determine the relationship between nutritional status and work environment with work fatigue of Police Officer at The Traffic Police Directorate of East Java. The design of this study was cross sectional, with 44 subjects aged 21-40 years. Data collection includes body weight and body height, subject identity data and work fatigue levels with the Industrial Fatigue Research Committee (IFRC) questionnaire. The independent variables were nutritional status and work environment and the dependent variables was work fatigue. Spearman’s Rank and Kolmogorov Smirnov test was used to analyze the relationship between nutritional status and work environment variables with work fatigue on the subjects. The correlation analysis between nutritional status and work fatigue was p = 0,000. The analysis between work environment and work fatigue was p = 1,000. There was a relationship between nutritional status and work fatigue, but there was no relationship between work environment and work fatigue of Police Officer at The Traffic Police Directorate of East Java.
The Effect of Edamame milk on Triglyceride Levels in Diabetes Wistar Rats
Authors: Ajeng Dhea , Ardiaria Martha , Kurniawati Dewi Marfu’ah , Ayustaningwarno Fitriyono
Published: January 2023

Type 2 diabetes is a hyperglycemic disease caused by cell insensitivity due to increasing blood glucose levels due to reduced insulin secretion. Hyperglycemia conditions have the risk to increase triglyceride levels in type 2 diabetes. Edamame milk contained isoflavones that had potential to reduce triglyceride level. To find out the effect of given edamame milk on triglyceride levels in type 2 diabetes wistar rats. A true experimental with pre-post randomized control group design towards 24 type 2 diabetes wistar rats in 4 groups. Groups K(+), P1 and P2 were induced Streptozotocin 45 mg/kgBW and Nicotinamide 110 mg/kgBW. P1 and P2 groups were given edamame milk at a dose of 1,8 ml/200grBW and 3,6 ml/200grBW for 28 days. Blood samples were taken through a retro-orbitalis plexus. Triglyceride levels were tested pre and post intervention using the GPO-PAP method. Data analysis had used Paired T test and One Way ANOVA test with Post hoc follow-up test. Triglyceride levels in P1 and P2 groups had significant differences (p<0,05) against the control groups. Edamame milk could reduce triglyceride levels of groups P1 and P2 at dose 1,8 ml/200grBW and 3,6 ml/200grBW. P2 was the highest group reduced in triglyceride levels up to 29,41±3,55 mg/dL. Edamame milk could reduced triglycerides levels in 28 days. Given an edamame milk at a dose 3,6 ml/200grBW more efficient to reduce triglyceride levels in type 2 diabestes rats significantly
The Physical Condition of The Sukoharjo Pencak Silat Athlete in Team Category
Authors: Khotimah Mutiara Nurul , Syaifullah Rony , Hendarto Singgih
Published: January 2023

Pencak silat is a sport related to physical needs and physical readiness to support the pencak silat movement. This study aims to determine the energy system in each stance, physical needs and to find out statistical data and the average physical need. This research is a descriptive quantitative with purposive sampling technique. Data were taken using the test items of Push Ups, Sit Ups, 300 M Run, Split Test, 20 M Sprint, Triple Jump, Shuttle Run, Ball Throw, Multi Fitnes-Stages. The research subjects were 6 people which were divided into 3 sons and 3 daughters. Data analysis used descriptive statistics. The results in the male sample showed perfect categories on the triple jump leg muscle power test and medicine ball throw arm muscle power test, very good on the push up arm muscle strength test, sit up abdominal muscle strength, anaerobic 300 m running test, side splits flexibility test, good category on the shuttle run agility test, above average category on Multi Fitnes- Stages, everage category on the 20 m sprint speed test. In the female sample, the results of the push-up arm strength test were in the very good category, the results of the sit-up abdominal muscle strength test were in the very good category, the results of the 300 m run test were in good and medium categories, the side splits test results were in good and medium categories, and the speed test results. 20 m sprint with less category, triple jump leg muscle power test results in good and sufficient category, shuttle run agility test results in sufficient category, medicine ball throw arm muscle power test results with perfect category, below average category endurance test results.
The state in the post-war industrial recovery and economic renewal: historical parallels and approaches for Ukraine
Authors:   State Institution “Institute for Economics and Forecasting, NAS of Ukraine”, Salikhova Olena , Krehivskyi Oleh ,   Secretariat of the Cabinet of Ministers of Ukraine
Published: January 2023

In 2022, Ukrainians are experiencing the most tragic events since the Second World War - the full-scale invasion of Russian troops into Ukraine has led to numerous casualties, the destruction of cities, and the disruption of infrastructure and industrial facilities. Since the first days of the war, the dependence on the industrial imports (primarily for military purposes) became obvious, as well as the fact that the ensuing socio-economic crisis cannot be overcome with domestic resources alone - both now and even after the end of the war. This prompts the search for mechanisms to ensure the stability and recovery of Ukraine's economy. The purpose of the article is to generalize the global experience of prioritizing the industry in the state policy of the leading countries of the world under the conditions of severe tests, to illustrate the implementation by the state of the functions speeding up economic recovery; and to propose conclusions and recommendations for Ukraine. The article shows the place of industry in the policy of recovery, gaining economic independence and increasing the country's power. Using historical examples, the authors demonstrated that during 300 years the state has influenced the industry through targeted political levers and institutional frameworks, generating the optimal results of measures aimed at restructuring to overcome the consequences of wars, epidemics and crises. It is substantiated that under the severe ordeals, the state has played a leading role in economic recovery, implementing a number of functions - administration and moderation, stimulation and catalysis, integration and cooperation, entrepreneurship and consumption, conservation and protection - to speed up the development of national industry as a source of the stabilization of employment, domestic and foreign investment, inflation, foreign trade and the financial sector, contributing to national social balance and well-being. The authors propose a conceptual approach to the functions of the state during post-war recovery of Ukraine's economy, ensuring economic stability and growth based on the national industry.
Science and innovation in Ukraine: approaches to policy making in times of war
Authors:   State Institution “Institute for Economics and Forecasting, NAS of Ukraine”, Gryga Vitalii , Ryzhkova Yuliia ,   State Institution “Institute for Economics and Forecasting, NAS of Ukraine”
Published: January 2023

The full-scale war started by Russia in Ukraine has caused many challenges for economic development, being the latter hardly imaginable without the contribution of research and innovation. Rebuilding R&I becomes another challenge for Ukrainian policymakers. Thus, the purpose of the paper is to analyze the R&I policy of Ukraine during the war caused by Russia and to develop policy recommendations for the postwar recovery. To achieve it, we used several methods, in particular expert opinion generalization, relevant scientific and policy literature analysis, and statistical analysis. The paper considers three approaches to innovation policy-making at crisis time: produce; procure; repurpose. Currently, Ukraine uses mainly the second one, by buying and receiving modern armament and equipment. Meanwhile, there were some innovative developments in Ukraine, which are not produced in sufficient quantities. After the war, Ukraine will no longer be able to buy armament due to fiscal constraints. Thus, in the short-run period, the government should reorient efforts toward repurposing current developments. However, such an approach is not sustainable in the long-run period, when the development of a broader S&T base is required to create a solid base for further repurposing in emergency cases. The war has caused massive damage to Ukrainian R&I potential, which by now is not fully measured and quantified. There are two types of damage: physical loss of research and innovation infrastructure (e.g. research facilities, and high-tech enterprises) and «brain drain», both of which should be the focus for R&I policymakers. Therefore, a set of policy measures is proposed to address the war-led challenges in R&I.
Historical Development of Political-Critical Thinking in Colombian Psychology
Authors: Cudina Jean Nikola , Ossa Julio César , Millán Juan David , López-López Wilson , Tateo Luca
Published: January 2023

The study traces the historical elements that have influenced the development of political-critical thinking in Colombian Psychology. Four historical periods have been identified and discussed: The intellectual colonialism of Colombian Psychology (1947-1960); the social Psychiatry in the years of La comisión [The commission] (1961-1980); the community Psychology and the coexistence (1980-1991); and the psychosocial studies after recent peace processes between government and armed groups (1991-2018). Colombian political Psychology did not follow a homogeneous and linear development. The reality experienced by Colombians during more than five decades of armed conflict required Psychology to abandon the direct paths of politics and opt for psychosocial studies that promise to be the most radical heirs of a generation of Latin American critical thinking as represented by Ignacio Martín-Baró, Maritza Montero and Silvia Lane.
Development and validation of RP HPLC method for the estimation of methyl paraben sodium and propyl paraben sodium in iron protein succinylate syrup
Authors: Javed Muhammad Faisal , Zahra Manzar , Javed Iqra , Ahmad Shahbaz , Jabeen Tayyaba , Ahmad Muhammad
Published: January 2023

A new precise, selective and reliable reversed phase high performance liquid chromatographic (RP-HPLC) method has been developed and validated for the determination of Methyl paraben sodium (MPS) and Propyl paraben sodium (PPS) (preservatives) in Iron protein succinylate syrup. Optimized conditions were; Methanol: Water (65: 35) as mobile phase, UV/Vis detector at the wavelength of 254 nm and flow rate was set at 1.3 ml min−1. By applying the set of conditions, separation of components was carried out in less than 7 min for both the analytes. The method was validated according to International conference of Harmonization (ICH) guidelines and the analytical characteristic parameters of validation included specificity, limit of detection (LOD), limit of quantification, linearity, accuracy, precision and robustness were evaluated. The calibration curve was found to be linear in the range of 0.045 mg mL−1 to 0.075 mg mL−1 for Methyl paraben sodium and 0.015 mg mL−1 to 0.025 mg mL−1 for propyl paraben sodium with a correlation coefficient r2 > 0.999. Accuracy; reported as percentage recovery was found to be in the range of 98.71%–101.64% for Methyl paraben sodium and 99.85%–101.47% for Propyl paraben sodium at 80%, 100% and 120% concentration for both the analytes. The proposed method was found to be precise and robust when evaluated by variations in wavelength, mobile phase composition, temperature and analyst. The limit of detection (LOD) was found 0.001 mg mL−1 (3 ppm) for Methyl paraben sodium and 0.001 mg mL−1 (1 ppm) for Propyl paraben sodium.
First record of the Delicate Salt Flat Mouse, Salinomys delicatus Braun & Mares, 1995 (Rodentia, Cricetidae) in a xeric environment of northwestern Córdoba (Argentina), with comments on its conservation status
Authors: Mignino Julián , Tarquino-Carbonell Andrea del Pilar , Ojeda Agustina A. , Teta Pablo
Published: January 2023

Salinomys delicatus Braun & Mares, 1995 is a sigmodontine rodent endemic to perisaline environments in west-central Argentina. It is currently considered to be a Vulnerable species due to its patchy distribution and the loss of optimal habitats caused by intensive anthropogenic activities. In this work, we document the first record for this species in the Dry Chaco ecoregion of northwestern Córdoba province (Argentina), enlarging the geographic distribution of this species by approximately 115 km to the east of previously known occurrences. Our new record highlights the need to strengthen conservation policies in the Dry Chaco of Córdoba province.
The open-access journal Biodiversity Observations: report for the period 2010-2022
Authors: Underhill Les G , Navarro Rene A
Published: January 2023

Between 2010 and 2022, the online journal Biodiversity Observations published 389 papers. In January 2023, the total number of downloads of these papers was 462,000. Between 2018 and 2022, 138 of the papers had been cited in Google Scholar, and had generated a total of 421 citations. The journal plans to continue publishing descriptive papers which report observations relating to biodiversity.
Descartes on Open Knowledge and Human Perfection
Authors: Kolesnykova T. O. , Malivskyi A. M.
Published: January 2023

Purpose. The purpose is to justify the validity of interpreting Descartes’ teachings as an enquiry into the search for forms and means of improving human nature, which implies a focus on the way he understands the openness of knowledge and education. The problem is considered from the perspective of representatives of university communities (teachers and librarians), historically included in the communication structure and system of the institution, including through the creation, management, use, preservation and dissemination of knowledge. Theoretical basis. One of the tenets of Descartes’ teachings is his desire to improve the human being. For our consideration, it is fundamentally important that Descartes uses "knowledge" not only in a narrow sense – as natural scientific knowledge, but also in a broader sense. In the context of the theme of the study, the most important case is when the thinker recalls the knowledge that every person experiences without referring to philosophy. It is this knowledge that, for Descartes, is key in resolving the central problem of his ethics – how can human nature be perfected? For our consideration of Descartes’ key points, it is fair to focus on the manifestation of the phenomenon of altruism in Descartes’ philosophy and on the representative fact of his inner openness – his willingness to engage in dialogue. He appreciates and encourages his interlocutors to turn to books, which are a form of representation of the vivid personalities of their authors. Originality. For the first time in the research literature, the thesis of René Descartes as one of the forerunners of the open knowledge system is substantiated. The arguments are given for the validity of Descartes’ interpretation of the demand of his own epoch for the search of effective forms of human improvement. Conclusions. The idea of justification of Descartes’ philosophical legacy as a predictor of open knowledge became possible under the condition of paying attention to the anthropological turn he made and finding substantive analogues of openness, including open education. Drawing on Christianity as the basis for altruism, Descartes demonstrates a caring attitude towards the achievements of previous generations on the path of personal self-development. His attention is rightly drawn to education and books as representations of vibrant personalities. Their authentic and productive assimilation is possible only under the condition of a caring attitude towards the public good, which involves the intellectual volunteering of teachers and librarians. It is about self-realization through altruistic self-improvement, i.e. intellectual charity, which is especially evident today during martial law in Ukraine and is voluntary, conscious and free work for the benefit of others.
Potwierdzenie testamentu wileńskiego złotnika Wincentego Slegla (1519). Przyczynek do dziejów elity mieszczańskiej Wilna i jej związków z Poznaniem
Authors:   Uniwersytet im. Adama Mickiewicza w Poznaniu, Manyś Bernadetta , Sliesoriūnas Gintautas ,   Lietuvos Istorijos Institutas
Published: January 2023

In the following paper the author attemps to analyse the confirmation of the testament of the Vilnian burger – craftsman, goldsmith and town councillor – Vincenty Slegel, written in the 1519.
Relacje szlachty wielkopolskiej z Żydami w świetle akt sejmiku województw poznańskiego i kaliskiego z lat 1668–1763
Authors:   Uniwersytet im. Adama Mickiewicza w Poznaniu, Bulińska Kamila
Published: January 2023

The article is an attempt to define the relationship between the nobility of Great Poland and the Jews on the basis of the issued local parliaments records of the Poznań and Kalisz voivodeships in the years 1668–1763.
Średniowieczne polonica i silesiaca ze zbiorów Archiwum Uniwersytetu Karola w Pradze
Authors:   Uniwersytet im. Adama Mickiewicza w Poznaniu, Tomczak Robert T.
Published: January 2023

The article presents a brief history of the medieval manuscript collections of the Charles University Archives in Prague which includes a catalogue of 13 medieval (1345– –1508) Polish and Silesian charters stored there
Slavic mutuality, Turkish-Slavic political connection and the vision of General Edmund Taczanowski
Authors:   Uniwersytet im. Adama Mickiewicza w Poznaniu, Prałat Emilian
Published: January 2023

The article is devoted to the discovered Greater Poland Military Museum in Poznań, the unpublished text of the memorial in French, which General Edmund Taczanowski, intended to address to the Turkish Sultan, in the hope of creating Bulgarian-Turkish troops, which were then to be used in battles with Russia.
Dziewiętnastowieczna historia Czechów w świetle ukraińskiej historiografii minionego trzydziestolecia (1991–2020)
Authors:   Uniwersytet Jagielloński, Świątek Adam
Published: January 2023

The article is an attempt to describe the achievements of contemporary Ukrainian historiography on the 19th century history of the Czechs and Czechia. The author analyzed syntheses, monographs and journal articles published in Ukraine in 1991–2020. In particular, three directions of research conducted in Ukraine were noticed: the Czech-Ukrainian intellectual, educational and cultural contacts in the Habsburg Monarchy, the Czech minority and its elites in the Ukrainian lands in the Russian Empire, and the history of the Czech lands in general.
Zarys działalności Stanisława Kary w służbie dyplomatyczno-konsularnej we Francji w latach 1932–1938
Authors:   Naukowiec Niezależny, Ambrochowicz-Gajownik Anna
Published: January 2023

The following article aims at providing an outline of the multifaceted activities of Stanisław Kara, the consul in Lille and Paris in the 1930s and the émigré counsellor at the Embassy of the Republic of Poland in Paris.
Exosomes: Recent Advances and Challenges as Targeted Therapeutic Delivery Vesicles
Authors: Jadhav Sourabh , Kumar Ankaj , Gulbake Arvind
Published: January 2023

The exosome is a naturally derived nanostructured lipid vesicle that ranges from 40-100 nm in size and is utilized to transport drugs, and biological macromolecules, including therapeutic RNA and proteins. It is a membrane vesicle actively released by cells to transport cellular components with a purpose for biological events. The conventional isolation technique has several drawbacks, including low integrity, low purity, long processing time, and sample preparation. Therefore, microfluidic technologies are more widely accepted for the isolation of pure exosomes, but due to cost and expertise requirements, this technology is also facing challenges. The bioconjugation of small and macro-molecules to the surface of exosomes is a very interesting and emerging approach for achieving the specific target, therapeutic purpose, in vivo imaging, and many more. Although emerging strategies resolve a few challenges, exosomes are still unexplored complex nano-vesicles with excellent properties. This review has briefly elaborated on contemporary isolation techniques and loading approaches. We have also discussed the surface-modified exosomes by different conjugation methods and their applications as targeted drug delivery vesicles. The challenges associated with the exosomes, patents, and clinical investigations are the main highlight of this review.
IN CELEBRATION OF PROFESSOR JOHN RICHARD THOME ON HIS 70TH BIRTHDAY
Authors: Cheng Lixin , Bai Bofeng , Xia Guodong , Zhang Hai-Bin , Guo Zhixiong
Published: January 2023

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Hypoxia-Inducible Factor 2α Attenuates Renal Ischemia-Reperfusion Injury by Suppressing CD36-Mediated Lipid Accumulation in Dendritic Cells in a Mouse Model
Authors: Qu Junwen , Li Dawei , Jin Jingsi , Sun Nan , Wu Jiajin , Yang Chao , Wu Lingling , Zhuang Shaoyong , Wu Haoyu , Chen Ruoyang , Ren Yaofei , Zhong Chen , Ying Liang , Zhang Yan , Yuan Xiaodong , Zhang Ming
Published: January 2023

Significance Statement

Hypoxia is a hallmark of renal ischemia-reperfusion injury (IRI) and serves as an essential regulator of innate immune responses during this process, although the mechanisms of this regulation remain unclear. Here, we showed in a murine model that HIF-2α knockout in dendritic cells (DCs) exacerbated renal IRI through activation of natural killer T cells. Mechanistically, HIF-2α deficiency upregulated CD36 expression of DCs, leading to cellular lipid accumulation. Pharmacologic inhibition of CD36 in DCs resulted in renoprotection by reducing lipid content and suppressing natural killer T cell activation. Our study strongly suggests that targeting the HIF-2α/CD36 regulatory axis may be a strategy for alleviating renal IRI.

Background

Hypoxia and hypoxia-inducible factors (HIFs) play essential and multiple roles in renal ischemia-reperfusion injury (IRI). Dendritic cells (DCs) comprise a major subpopulation of the immunocytes in the kidney and are key initiators and effectors of the innate immune responses after IRI. The role of HIF-2α in DCs remains unclear in the context of renal IRI.

Methods

To investigate the importance of HIF-2α in DCs upon renal IRI, we examined the effects of DC-specific HIF-2α ablation in a murine model. Bone marrow–derived DCs (BMDCs) from DC-specific HIF-2α–ablated mice and wild-type mice were used for functional studies and transcriptional profiling.

Results

DC-specific ablation of HIF-2α led to hyperactivation of natural killer T (NKT) cells, ultimately exacerbating murine renal IRI. HIF-2α deficiency in DCs triggered IFN-γ and IL-4 production in NKT cells, along with upregulation of type I IFN and chemokine responses that were critical for NKT cell activation. Mechanistically, loss of HIF-2α in DCs promoted their expression of CD36, a scavenger receptor for lipid uptake, increasing cellular lipid accumulation. Furthermore, HIF-2α bound directly to a reverse hypoxia-responsive element (rHRE) in the CD36 promoter. Importantly, CD36 blockade by sulfo-N-succinimidyl oleate (SSO) reduced NKT cell activation and abolished the exacerbation of renal IRI elicited by HIF-2α knockout.

Conclusions

Our study reveals a previously unrecognized role of the HIF-2α/CD36 regulatory axis in rewiring DC lipid metabolism under IRI-associated hypoxia. These findings suggest a potential therapeutic target to resolve long-standing obstacles in treatment of this severe complication.