bluuebunny/crossref_metadata_2025 huggingface dataset:
A estrutura do ouvido: Cicatrizes
Authors: Nuesch Enrique
Published: January 2025

O artigo trata de mostrar que há uma “estrutura do ouvido” tacitamente anunciada por alguns textos de Derrida, produzida pelo seu próprio gesto de cortar notas, orações e frases de seus textos ao longo dos anos. Especificamente, examina-se a relação entre Otobiographies (Derrida, 1984), “Prénom de Benjamin” (Derrida, 1994a) e “Geschlecht IV” (Derrida, 1994b). Propõe-se que se podem ouvir outros sentidos no que se diz em “Prénom de Benjamin”, seguindo as cicatrizes desses cortes nos textos em suas diferentes versões. A exposição começa considerando momentos da relação de Derrida com o Estruturalismo, derivando daí que essa relação pode ser caracterizada pela multiplicação de estruturas, aproximando-se dos traços que Deleuze (1972) reconhecia como “estruturalistas”. Logo, entra-se na substância do artigo tendo em mente que uma “estrutura do ouvido” se projeta em negativo ao se acompanharem as considerações explícitas de Derrida acerca do ouvido constrasando-as com o que se ouve nos cortes realizados em seu texto.
O mal-estar no estruturalismo - ambivalências da demanda por justa representação no campo da arbitrariedade do signo
Authors: Rocha Pinezi Gabriel Victor
Published: January 2025

O artigo tem como objetivo discutir certo mal-estar ético e político no pensamento estruturalista — especialmente na desconstrução derridiana e em seus herdeiros — segundo o qual as estruturas seriam, simultaneamente e paradoxalmente, origem e causa de toda liberdade e de toda violência. Problematizamos tal hipótese dividindo o artigo em três partes: na primeira, analisamos as teses de Saussure sobre a arbitrariedade do signo com base na leitura mais atual de Patrice Maniglier (2023); em seguida, discutimos em que medida as teses saussurianas retomam conceitos e ideias próprias ao Crátilo, de Platão; na terceira, apontamos para alguns impasses da desconstrução derridiana no trato com o conceito de justiça a partir do embate com Saussure e Platão. Com isso, concluímos que o mal-estar no estruturalismo parece derivar de um uso hiperbólico das metáforas da “justiça” e da “violência” aplicadas ao problema da representação de modo a retomar a hipótese platônica da “correção” e da “justiça” dos nomes.
Human Nature in Ancient Philosophy and its Influence On Modern Philosophy
Authors: Huong Nguyen Thi Thu , Thanh Nguyen Van , Hoan Nguyen Minh
Published: January 2025

The concept of "human nature" is analyzed from the perspective of classical philosophy, with a focus on the thought of Mencius, a great Confucian philosopher. Mencius believed that human nature is inherently good and has the potential to develop morality through education and training. This view has continued to influence modern philosophical and moral theories, such as existentialism and materialism. Through a comparison of ancient and modern philosophical perspectives, the article clarifies the connection between traditional thought and modern theories, helping to better understand the role of human nature in building today's society and morality.
As estruturas estão “suspensas no ar”? Um dialogue manqué entre Louis Althusser e Claude Lévi-Strauss
Authors: Balbino Lorena de Paula
Published: January 2025

O artigo tem como objetivo discutir as críticas que Louis Althusser faz às noções de estrutura e inconsciente na obra de Claude Lévi-Strauss. Procuramos, assim, reconstituir a trajetória das críticas althusserianas, desde sua discussão sobre a noção de estrutura e tempo histórico, publicada na obra coletiva Lire le Capital, até as críticas à noção de inconsciente e à abordagem etnológica das sociedades ditas primitivas, presentes em cartas do autor que permaneceram inéditas até a década de 1990. A partir da confrontação com o texto lévi-straussiano, mostramos que a crítica de Althusser não se resume a uma mera comparação entre as teses antropológicas e as teses marxistas, mas que ela aponta para uma exigência fundamental, a de uma função epistemológica que permita explicar a necessidade de uma determinada estrutura social.
Pemberian Informasi Terkait BUD (Beyond Use Date) Sediaan Farmasi di Apotek Kimia Farma Banjarbaru
Authors: Hamida Syaputri Kharin , Muthia Sari Okta , Riduan Ahmad , Setiawan Deni
Published: January 2025

Beyond Use Date (BUD) adalah batas waktu penggunaan suatu produk obat setelah kemasan primernya dibuka. Tingkat pengetahuan masyarakat Banjarbaru terkait Beyond Use Date ini masih terbilang kurang dikarenakan masih sedikitnya penyebaran informasi yang menggaungkan tentang edukasi BUD suatu obat. Tujuan kegiatan ini untuk meningkatkan pengetahuan pengunjung apotek Kimia Farma tentang Beyond Use Date sediaan farmasi. Promosi kesehatan ini menggunakan metode ceramah menggunakan media leaflet. Kegiatan dimulai dengan pengisian kuesioner sebelum pemberian informasi, penyampaian materi, tanya jawab, dan pengisian kuesioner sesudah pemberian informasi. Sebanyak 10 responden ikut dalam kegiatan. Hasil pelaksanaan promosi kesehatan di Apotek Kimia Farma Amaco Banjarbaru yakni rerata pengetahuan tentang Beyond Use Date sebelum pemberian informasi sebesar 42% dan sesudah pemberian informasi sebesar 96%. Kesimpulan kegiatan ini adalah terjadi peningkatan pengetahuan pengunjung apotek Kimia Farma tentang Beyond Use Date.

Kata kunci: obat, batas penggunaan obat, efektivitas, tanggal kadaluarsa
Thực trạng quản lý hoạt động ứng dụng công nghệ thông tin trong dạy học ở các trường trung học phổ thông thành phố Bạc Liêu, tỉnh Bạc Liêu
Authors: Nguyễn Văn Đệ , Lâm Tố Hữu
Published: January 2025

Ngày nay, công nghệ thông tin đã trở thành một công cụ không thể thiếu trong dạy học tại các trường trung học phổ thông. Quản lý ứng dụng công nghệ thông tin trong dạy học đã trở nên cần thiết để các trường chú trọng đến chất lượng giảng dạy và nâng cao hoạt động của nhà trường. Sau khi nghiên cứu lý luận về quản lý ứng dụng công nghệ thông tin trong dạy học, tác giả đã tiến hành phương pháp khảo sát bằng bảng hỏi và phỏng vấn trên 138 khách thể gồm cán bộ quản lý và giáo viên của các trường trung học phổ thông trên địa bàn thành phố Bạc Liêu, tỉnh Bạc Liêu, nhằm tìm hiểu thực trạng quản lý hoạt động ứng dụng công nghệ thông tin trong dạy học ở trường trung học phổ thông.  Thông qua kết quả khảo sát nhận thấy, tuy công tác quản lý hoạt động ứng dụng công nghệ thông tin trong dạy học ở trường trung học phổ thông có nhiều tiến bộ nhưng cũng còn nhiều nội dung cán bộ quản lý cần quan tâm để nâng cao hiệu quả ứng dụng công nghệ thông tin trong dạy học trong các nhà trường. Trên cơ sở đánh giá thực trạng, làm đề xuất các biện pháp quản lý hoạt động ứng dụng công nghệ thông tin trong dạy học ở các trường trung học phổ thông ở thành phố Bạc Liêu, tỉnh Bạc Liêu trong bối cảnh đổi mới giáo dục hiện nay.
FREQUENCY OF POST-OPERATIVE COMPLICATIONS IN PATIENTS ASSOCIATED WITH IMPACTED MANDIBULAR THIRD MOLAR REMOVAL
Authors: Fahimuddin  , Naeem Kashmala , Kayani Harmain , Ashraf Nadia
Published: January 2025

Objectives: To determine the frequency of postoperative complications associated with impacted mandibular third molar removal in patients presenting to a tertiary care hospital (Hayatabad Medical Complex, Peshawar)
Material and Methods: A descriptive Cross-sectional study was conducted on 132 patients with post-op complications after third molar removal. Both genders and patients ages 17 to 60 were added. Patients with missing clinical history, radiographs, and fractured mandibles were excluded from the study. Postoperative complications were recorded on a predesigned proforma.
Results: Mild pain was found in 49 (37.1%) patients, moderate pain was found in 71 (53.8%) patients, and severe pain was recorded in 12 (9.1%) patients. Dry socket was found in 16 (12.1%) patients. Infection was found in 5 (3.8%) patients. Inferior alveolar nerve (IAN) damage was found in 3 (2.3%) patients and Lingual nerve damage was found in 6 (4.5%) patients.
Conclusion: In our study, the postoperative complications of concerns in patients associated with impacted mandibular third molar removal were dry socket in 12.1% of patients, infection in 3.8% of patients, IAN nerve damage in 2.3% of patients, and lingual nerve damage that was found in 4.5% patients.
 
Key Words: Complications, mandible, third molar surgery
EFFICACY AND SAFETY OF SUBLINGUAL MISOPROSTOL FOR CERVICAL PRIMING BEFORE MINOR GYNECOLOGICAL PROCEDURES
Authors: Mazhar Tayaba , Bukhari Naila
Published: January 2025

OBJECTIVE
To assess the efficacy and safety of 400 micrograms of sublingual misoprostol in comparison to the same dose of vaginal misoprostol for cervical priming before minor gynecological procedures.
MATERIALS AND METHODS
The Randomized Controlled Trial was conducted in Khyber Teaching Hospital from 1st April 2021 to 31st Oct 2022. The sample size was 212, and a convenient random sampling technique was used. Fifty percent of the patients were given sublingual misoprostol 400 micrograms 2 hours before surgery (group A), while the rest were given 400 micrograms vaginal misoprostol 4 hours before surgery (group B). Efficacy of procedure was defined as the measure of pre-procedural cervical width as measured by the largest number of cervical Hagar’s dilators passing easily through the cervix. At the same time, safety was the measure of less or no occurrence of side effects related to misoprostol and procedure, such as fever, chills, vomiting, diarrhea, vaginal bleeding, cervical injury, or uterine perforation. All data was stored and analyzed in SPSS 20.
RESULTS
The mean age of patients in group A was 38.99 ± 7.82, and in group B 37.97 ± 7.30, The Mean parity in group A 2.98 ± 2.32 and in group B was 3.05 ± 1.67, Mean uterine size in group A
10.83 ± 1.80 and in group B 9.93 ± 1.81, and the mean pre-procedural cervical width in mm in group A was 8.57 ± 0.74 and in group B 8.01 ± 0.41(p-value 0.002). Complications included minor side effects like nausea and uterine cramps.
CONCLUSION
Sublingual misoprostol is an effective and safe agent for cervical ripening and dilatation before minor gynecological procedures. The effect of sublingual misoprostol 2 hours before the minor procedures is more effective compared to the same dose of vaginal misoprostol when given 4 hours prior.
KEYWORDS
Misoprostol, Sublingual, Cervical width, cervical priming, minor gynecological procedures.
THE EFFECTIVENESS OF AN OPERATIVE DECOMPRESSION TECHNIQUE FOR THE MANAGEMENT OF CALCIFIED LUMBER DISC HERNIATION
Authors: Kadhim Abbas A. , Aljanabi Ali Saleh , Hakim Wissam Saleh
Published: January 2025

Objective: To determine the effectiveness of a new decompression surgical intervention for the management of calcified lumber disc herniation (CLDH).
Patients and methods: This prospective cohort study was conducted in the orthopedic center at Adiwaniyah Teaching Hospital, Adiwaniyah Province in Iraq. The study enrolled 72 patients, 37 females and 35 males, with an age range of 65 to 75. Inclusion features were subjects with calcified lumber disc herniation who presented with a low backache with radiation to the leg, which remained the same for at least six months despite conservative measures such as pharmacological agents and physiotherapy. The pain affected the patients' daily activities.
Results: The mean visual analog score was reduced after three months from a baseline reading of 7.03 ±1.02 to 3.29 ±1.05 (p< 0.05), and it was further reduced one year later to 2.07 ±0.93 (p<0.01). The Oswestry Disability Index (ODI) score was reduced after three months from a baseline reading of 53.27 ±8.37 % to 12.38 ±4.29 % (p< 0.01), and it was further reduced one year later to 8.91 ±1.93 % (p<0.01).
Conclusion: The surgical procedure used in the present study relieved pain and significantly improved functional outcomes compared with the baseline pre-surgical status. 
Keywords: Calcified lumber disc herniation, surgical decompression, children calcification, intervertebral disc (IVD) degeneration
Study of PV Module for Characterizations Using MATLAB Simulink and Tracking of Maximum of PV Power
Authors: Radak Blange
Published: January 2025

Solar energy is the primary renewable energy source, and solar photovoltaic (PV) cells utilise sunlight to generate power for utility applications. The output of PV power varies as a direct current, depending on the intensity of the sunlight. Therefore, understanding the behaviour of PV power in terms of electrical power, voltage, and current is crucial to effectively tracking and extracting the maximum power from the PV system. In this paper, we have configured the parameters of the PV cell using a reference PV module and modelled it within the MATLAB Simulink environment, taking into account changing atmospheric conditions. We successfully simulated the PV characteristics, specifically maximum power, voltage, and current, through a stepwise variation of incoming irradiance and ambient temperatures. The results of these simulations were then compared with data from the actual reference PV cell. The PV model we employed has successfully verified and validated the parameters against the provided actual reference PV module in the MATLAB Simulink environment, yielding results that closely match the actual datasheet specifications.The PV power is  Solar Insolation(S) and ambient temperature(T) dependence. Hence its Maximum power point is to be correctly tracked down. The Maximum power tracking using Perturb and Observe and Fuzzy Logic Based MPPT algorithms have been evaluated and compared.from the result it is seen that Fuzzy Logic MPPT is much better than that of conventional PO.
On-Site Testing and Certification of Large-Size Concentrating Tracking Solar Thermal Collector for Medium-Temperature CSP or SHIP Plants
Authors: Sallaberry Fabienne , García de Jalón Alberto , Mutuberria Amaia , Bernad Ignacio , Ubach Josep , Ajona Jose , Sanchez Marcelino
Published: January 2025

The certification of large-size Linear Fresnel Reflector (LFR) or variable geometry collectors is possible through international standards ISO 9806 and IEC 62862-5-2. However, those concentrating solar collectors have a large-size design that makes it more complicated to test in an accredited permanent laboratory. So, the most common way to accredit those solar products is through on-site testing. In this study, one large-size LFR and one boosted Evacuated Tube Collector (ETC) with lateral reflectors were tested in-site according to the standard ISO 9806.
Estimating scenic beauty in Chinese villages: a novel approach based on 3D real scene models
Authors: Wu He , Dai Wen , Wang Chun , Cen Yiyi , Jia Wenzheng , Tao Yu , Fan Mengtian
Published: January 2025

The color landscape is an essential aspect of each village, representing both natural scenery and human history. However, previous research has not provided a thorough and quantitative assessment of the color spatial pattern of regions and their surroundings. In this study, color patches were extracted from 3D real scene models, and color landscape indices were used to quantify the color landscape pattern. A questionnaire was utilized to establish the association between the color landscape indices and the Scenic Beauty Estimation (SBE) scores, which was then used to predict the SBE without the need for another questionnaire. The results showed that: 1) the color landscape indices extracted using 3D real scene models can reveal the scenic beauty of villages, with different villages presenting various color landscape patterns; 2) the SBE scores obtained through the questionnaire have a strong correlation with various color landscape indices, such as COHESION, LPI, SPILT, Y-MPS, and GE-MPS; 3) the SBE model based on color landscape indices was developed using stepwise linear regression, with an R2 value of 0.822 and an average error of 0.248, which can predict SBE in various places without the use of a questionnaire. This study introduces a new perspective and approach for estimating scenic beauty, which will help with rural planning and beautiful countryside development.
Chaucer’s Complaint to His Purse and Authority in the World
Authors: Olson Paul A.
Published: January 2025

Chaucer’s Complaint to His Purse concerns more than the poet’s financial need under the new Lancastrian administration. It speaks to the limits of Henry IV’s royal authority and, through irony, to the limitations of Chaucer’s purse’s power. Underlining royal limits, Chaucer petitions the king as one who holds office through election and line but not conquest, which is Henry’s position on his office as well. In speaking ironically of the purse’s authority, the poet addresses the gold that the monarch might grant him as if it constituted a human or divine patron, but he does so in a hierarchy of ascending irony that shows gold’s limits. In the envoy, Chaucer drops irony and turns seriously to the monarch and government that can, with their limited powers, help him.
“Thow most a fewe of olde stories heere”: Past and Future Prophecies in Troilus and Criseyde
Authors: Easler Jennifer Nicole
Published: January 2025

In Troilus and Criseyde, Geoffrey Chaucer uses the Trojan War as a backdrop for the romance of the Trojan prince Troilus and his beloved Criseyde, a traitorous prophet’s daughter and an eventual betrayer herself. Moments of prophecy complicate the poem’s epistemological questions, and so this article examines the ways Chaucer uses prophecy to explore the uncertainty of knowledge and the nature of impermanence. The poem depicts two prophets: Calchas, Criseyde’s father, is a traitor who predicts the future; and Cassandra, Troilus’s sister, prophesies once by discussing the past. These prophets are hardly the poem’s focus, but they serve as both parallels with and contrasts to Troilus and Criseyde themselves. Calchas, who turns towards the future with certainty, adopts a fatalistic attitude—an attitude his daughter comes to share—while Cassandra, who turns towards the past with openness to uncertainty, finds consolation for impermanence, a consolation Troilus finds in death.
Mysticism and Visual Theology: The Sacred Image and Gaze in Saint Teresa of Ávila
Authors: Onofre Dario Velandia
Published: January 2025

Given the immense complexity contained in the literature and testimonies of a crucial age in the consolidation of the Catholic reform, Saint Teresa of Ávila’s literary works have been studied from many perspectives. Nonetheless, the possible relationship between a mystical theology and a visual theology has not been given sufficient attention. The present article intends to demonstrate how the Saint’s books helped consolidate a theology of visual practices that defends the power of sacred images and the sacred gaze.
Minne, Translated: Embodying Liturgy, Love, and Pandemic Trauma in the Diepenveen Sister-Book and a Revelation from Facons
Authors: Perk Godelinde Gertrude
Published: January 2025

This article traces how individual and collective trauma interplay in pandemic trauma by anatomizing the aftershocks of plague in two late medieval vernacular texts produced by Devotio Moderna communities of Augustinian canonesses regular, a sister-book from Diepenveen (northeastern Low Countries; present-day Netherlands) and a visionary text from the convent of Facons in Antwerp (present-day Belgium), Visioen en exempel by Jacomijne Costers (d. 1503). It scrutinizes how trauma intervenes in the liturgy and vice versa in each text, mapping how trauma inflects mutual charity (minne), prescribed as protection against plague. Allowing medieval trauma to interrogate modern trauma theory, this discussion participates in debates about the ethics of the weaponization of trauma.
Holiness and Black Consciousness: The Social Witness of Black Saints, Shepherds, and Sages
Authors: Sanders Cheryl J.
Published: January 2025

Charles Price Jones and Charles Harrison Mason nurtured a programme of Black religion, identity, and culture during the formative decades of the Holiness and Pentecostal movements in the United States. This article disentangles the intertwined Black Holiness and Pentecostal traditions in an effort to describe the distinctive worship, lifestyle, and social awareness of Black saints. It considers the redemptive potential of holy Black consciousness to achieve three goals: revitalize Christian unity, restructure a progressive Christian identity, and reconfigure Christian pedagogy to promote resistance of racism and other forms of social injustice Black people experience in the church and society.
Pedagogy and Preaching in Edwardian Oxford: Ernest and Margaret Genner
Authors: Wellings Martin
Published: January 2025

Ernest Ely Genner (1877–1930) and his wife Margaret (1871–1933) exemplified late-Victorian Wesleyan aspirations, benefiting from educational opportunities to achieve academic and professional success. In two ways they pressed beyond the generality of middle-class Wesleyans in this period: Ernest Genner occupied a unique position as an Oxford don who made no secret of his Wesleyan loyalties, combining decades of tutorial teaching with long service as a local preacher; Margaret pursued higher education for herself and supported women students in the decades when the battle for women’s admission to Oxford University was fought and won.
‘Break[ing] the System’: How the Methodist Student Movement Motivated a Generation to Challenge Their Denomination’s Segregationist Polity
Authors: Chastain Emily Nelms
Published: January 2025

The Methodist Student Movement (MSM) emerged just before the 1939 denominational inauguration and catalyzed engaged youth within the Methodist Church. Facilitated through national to local leadership, it aimed at educating and empowering young adults via Wesley Foundations, National Conferences, and civic involvement. Its work turned contentious as youth pressed for quicker desegregation in defiance of the Church’s sluggish stance. This conflict highlighted a divergence in theological adherence regarding equality, leading to the gradual dissolution of MSM tools and youth participation. The denomination’s reluctance to address segregation aligned with its theological discipline clashed with the urgency felt by MSM members. The General Conference’s slow response led to the disappearance of organizational support and youth involvement, underscoring the clash between tradition and the evolving social conscience.
In Search of an Integrative Method to Study Unconscious Processing: An Application of Bayesian and General Recognition Theory Models to the Processing of Hierarchical Patterns in the Absence of Awareness
Authors: Prieto Antonio , Montoro Pedro R. , Jimenez Mikel , Hinojosa José Antonio
Published: January 2025

The dissociation between conscious and unconscious perception is one of the most relevant issues in the study of human cognition. While there is evidence suggesting that some stimuli might be unconsciously processed up to its meaning (e.g., high-level stimulus processing), some authors claim that most results on the processing of subliminal stimuli can be explained by a mixture of methodological artefacts and questionable assumptions about what can be considered non-conscious. Particularly, one of the most controversial topics involves the method by which the awareness of the stimuli is assessed. To address this question, we introduced an integrative approach to assess the extent to which masked hierarchical stimuli (i.e., global shapes composed of local elements) can be processed in the absence of awareness. We combined a priming task where participants had to report global or local shapes, with the use of subjective and objective awareness measures collected either in a separate block (offline), or trial-by-trial during the main task (online). The unconscious processing of the masked primes was then evaluated through two different novel model-based methods: a Bayesian and a General Recognition Theory modeling approach. Despite the high correlation between awareness measures, our results show that the use of alternative approaches based on different theoretical assumptions leads to diverging conclusions about the extent of the unconscious processing of the masked primes.
Affect during sleep: Exploring the capabilities of Artificial Intelligence in Sleep Research
Authors: Ernst Sharon , Krauss Daniel , Moss Moritz , Vossiek Martin , Eskofier Bjoern , Berking Matthias
Published: January 2025

Clinical research demonstrates the bidirectional associations between affect and sleep: Major depressive disorder is a prevalent clinical disorder, characterized by alterations in affect and sleep. Conversely, sleep disturbances emerge as prodromal manifestations preceding the onset of the disorder. Despite these close links, few studies investigated depressed daytime affect and its bidirectional associations with sad affect at the time of sleep. This lack of evidence can be attributed to methodological constraints, challenging the assessment of affect during sleep. To address this research gap, the present study introduces an innovative method utilizing Machine Learning and Infrared technology for the unobtrusive assessment of affect during sleep. The objectives of the present proof of concept were as follows: First, to introduce a novel approach for measuring affect during sleep. Second, to determine the bidirectional associations of depressed affect at daytime and sad affect during sleep in a healthy sample. Sad affect during sleep was measured using three infrared cameras with adaptive night vision, recording 63 videos during sleep. Daytime depressed affect was measured by survey, data analysis included general linear modeling (GLM). In line with the first objective, sad affect during sleep was extracted from video-based facial expressions using Artificial Intelligence software frameworks open DBM and open Face (AiCure). In line with the second objective, GLM analysis yielded that higher levels of depressed affect at daytime predicted higher levels of sad affect during sleep significantly. The inverse association was not significant. Conclusionally, we present an innovative method for the unobtrusive measurement of affect during sleep. This method may be particularly advantageous for the early detection of depressed mood states in subclinical populations and samples undergoing transient depressed mood states. Clinical and general implications are discussed.
Drug Delivery Systems for Clinically used Drugs for Cardiac Amyloidosis Treatment: Preparation and Properties
Authors: Uspenskaya Mayya V. , Snetkov Petr P. , Generalova Yuliya E. , Morozkina Svetlana N.
Published: January 2025

Cardiac amyloidosis is one of the leading causes of restrictive cardiomyopathy. It is typically rapidly progressive diastolic dysfunction in a non-dilated ventricle. Due to the numerous molecular pathways involved in the development andprogression of the disease, the drug molecules useful for cardiac amyloidosis are represented only by two small molecules, introduced in clinical application relatively recently. Here we present the comparative analysis of drug delivery systems for tafamidis and diflunisal, which have been developed in our group. The biosafe and biodegradable polymeric matrixes such as hyaluronic acid, chitosan and PVA have been used. The concentration dependence and the influence of polymer matrix on drug release discussed. Important, that no burst character of release was detected in all developed drug delivery systems.
Heat and Low-Density Lipoprotein Transfer in Healthy Aorta using Two-Way Fluid-Structure Interaction Method
Authors: Qiao Yonghui , Luo Kun , Fan Jianren
Published: January 2025

This study aims to reveal the mechanism of heat and low-density lipoprotein (LDL) transfer in healthy aortas leveraging a fluid-structure interaction model. Two healthy aortic geometries are reconstructed. The pulsation and non-Newtonian viscosity of blood flow are considered. The aortic wall is assumed to be hyperelastic. Results show that there is a strong positive correlation (>0.596) between the LDL and wall temperature. The long relative residual time region also coincides with the high LDL, which negatively correlates with wall shear stress and topological shear variation index. This study would inform novel strategies to measure LDL concentration and regulate its accumulation.
Pharmacological Inhibition of RUNX1 Suppresses Cardiac Cathepsin Expression and Preserves Cardiac Function Following Myocardial Infarction in Rats
Authors: He Weihong , Chen Hengshu , Chen Kexin , Li Tiantian , Wu Simiao , Wang Si
Published: January 2025

Cardiac cell death following myocardial infarction (MI) leads to irreversible loss of myocardium which in turn leads to adverse structural and functional changes of the heart, referred to as cardiac remodelling. Progression of adverse remodelling causes heart failure which is linked to increased deaths or hospitalizations. Runt-related transcription factor-1 (RUNX1) is a member of the core-binding factor family of transcription factors which regulate gene expression. Recent evidence showed that RUNX1 expression is increased following MI and negatively correlates with cardiac function. Dr He’s previous study performed with a cardiomyocyte-specific Runx1-deficient mouse revealed that reducing RUNX1 function preserves myocardial contractility and prevents adverse cardiac remodeling. Cathepsin is a family of lysosomal proteases and is involved in multiple cell death pathways. Our recent study showed that inhibition of RUNX1 reduced infarct size after acute MI, paralleled with repressed cardiac cathepsin levels. The present work sought to investigate whether the inhibition of RUNX1 preserves cardiac function post-MI. MI was surgically induced by performing coronary artery ligation and echocardiography was used to assess cardiac function. Here, we report that cardiac systolic function, as indicated by fractional shortening, decreased in control rats. In contrast, rats treated with RUNX1 inhibitor Ro5-3335 demonstrated a markedly preserved fractional shortening that was 128% of the control animal at 1-week post-MI (39.1±1.4% versus 30.6±2.9%; P<0.05). This beneficial effect is in line with our previous work and might be due to repressed cathepsin expression as revealed by our recent proteomic study. Taken together, our data demonstrate that pharmacological inhibition of RUNX1 not only reduces infarct size but also preserves cardiac function following MI, thereby suggesting the translational potential of RUNX1 as a new therapeutic target for cardiac protection against MI.
A Narrative Study of Mask Wearing Behavior based on A PPP Model
Authors: Chen Qiuru , Yin Hui
Published: January 2025

Mask wearing is an important public health measure to prevent a number of communicable diseases including COVID-19, but the public react differently to mask wearing guidelines. This paper established a triple-influence “PPP Model” that combines mask policies (policy), risk perceptions (perception) and risk-aversion preferences (preference), and conducted narrative analysis of mask wearing behaviors of the public in the United States, Germany, Brazil, India, Japan, and South Africa during COVID-19 pandemic. By comparing those factors influencing public mask wearing behavior among different countries, this paper provides a reference for cross-cultural research on public mask wearing behavior, and for policy makers to design and implement public health measures precisely and effectively in the face of public health emergencies.
Voltammetric Analysis of Cadmium in Blood and Urine using Hanging Mercury Drop Electrode (HMDE)
Authors: Jaiswal Ashok Kumar
Published: January 2025

Background: Cadmium (Cd) is a metallic element present everywhere in our environment. It is inflammable, but in its powdered form, it releases toxic fumes which cause cadmium poisoning. The disease caused by exposure to Cd is known as Itai -Itai (ouch-ouch) disease. Various sophisticated analytical techniques like ICP-MS, AAS, etc. are usually used to assess levels of cadmium in biological samples. An attempt has been made to develop the method for the determination of cadmium in blood and urine with a voltammetric technique using Hanging Mercury Drop Electrode (HMDE). Objective: To develop a simple and reliable method for voltammetric analysis of cadmium in blood and urine using Hanging Mercury Drop Electrode (HMDE). Methods: Blood and urine samples were spiked with cadmium. The samples were processed by the closed digestion method using nitric acid. Voltammetry determination of cadmium in the samples was carried out using Hanging Mercury Drop Electrode (HMDE). Voltammograms of blank, sample and standard were recorded. Extrapolation graph gives the amount of Cd present in the sample. Results: The concentration of cadmium was successfully detected in all the spiked blood and urine samples. The method is suitable for the determination of cadmium in blood and urine. The limit of detection of the method is 0.1 µg/L for cadmium. Conclusion: The developed voltammetry method is a simple, selective, sensitive, and reproducible technique for the quantitative determination of cadmium in blood and urine using Hanging Mercury Drop Electrode (HMDE).
Dendritic crystal formation and growth of biological solutions and its AI aided image analysis for medical applications
Authors: Huang Yao-Xiong
Published: January 2025

The studies on the dendritic crystallization of biological solutions are significant for medical applications. This manuscript reports our systematic study on the solution dendritic crystallization as a function of temperature, pH value, and the concentrations of its major components. And the factors that cause the variation in the crystal patterns, the distribution of the main components in the crystals, and the sequence of their deposition or crystallization. By summarizing the general crystallization behavior and formation mechanisms of biological solutions, we proposed the methods of crystal pattern analysis for the solution characteristics tests or growing the crystals with desired patterns for different purposes. By the methods, one can conduct a quantitative test on a solution by analyzing its evaporated crystallization patterns. Therefore, the chemical compound measurements that usually need to use analytical instruments can be transferred to simple pattern recognition and analysis and make it become an objective test. With a smartphone-based portable imaging device, the crystal pattern analysis method can be a powerful means for daily use of medical and biochemical point-of-care testing (POCT). On this basis, we developed a simple smartphone-based salivary crystallization imaging system with functions of AI-aided rapid automatic pattern recognition and analysis to help pregnant women monitor their fetus status daily at home and predict their delivery date by analyzing their saliva crystallization. The method combines the information of the fractal dimension with some specific forms of crystals in the salivary crystallization and estimates the delivery date in both quantitative and qualitative manners. The accuracy of the prediction was satisfactory, with 100% delivery in the predicted week, 93.3% within the three days, and 86.7% on the day as the prediction. Besides pregnant women's delivery date estimation, the detecting system would be valid for other medical applications.
Citizenship Socialization Process and National Integration
Authors: Ladan Sirajo Alhaji , Bello Samaila
Published: January 2025

Efforts at nation-building in Nigeria are hindered by various social problems linked to the low level of national integration among its religiously, regionally and ethnically diverse population. This paper examined citizenship socialization courses and subjects at the three (3) levels of education (Basic, Secondary and Tertiary) in Nigeria that are designed to promote national integration. The courses and subjects include Citizenship Education, Civic Education and General Studies (Peace Studies and Conflict Resolution and Nigerian Peoples and Culture). Similarly, key concepts such as socialization, citizenship socialization courses and national integration are conceptualized. The Functionalists sociological perspective was adopted as a theoretical framework to establish the link between citizenship socialization courses and subjects and promotion of national integration. However, despite the link or potential of citizenship education in raising the level of national integration, the paper identified some constraints on the extent to which citizenship socialization courses and subjects promote the desired national integration among the people of Nigeria. These challenges include the current assessment methods in schools, which focus on testing cognitive rather than affective abilities, the problem of inadequate funding of education in general, large size lecture halls and other poor teaching and learning conditions and Low credit units or time on the time table on specific curriculum subjects and courses meant citizenship socialization for national integration. To address these challenges, the paper suggests diversifying assessment and evaluation methods, among other strategies, to improve the teaching of citizenship socialization courses and promote national integration in Nigeria.
An Interactive Approach of Teaching and Learning Prerequisite Mathematics Course and Core Engineering Mathematics Course During COVID-19 Pandemic
Authors: Fasinu Vojo George
Published: January 2025

The emergence of COVID-19 brought up some concerns and changes in the approaches to the teaching and learning of some engineering related modules, particularly in South Africa. Therefore, the teaching of an electronics engineering course demands a balanced interactive approach, as requested by the curriculum. On this note, this paper reports the common approaches of teaching and learning mathematical modelling in antenna theory and design. It also discusses the perceived impact of interactive learning on modelling some mathematical skills in engineering education. It emphasizes the form of interaction that exists among students and lecturer, lecturer and students, and the whole class with the lecturer. The paper therefore reports the strategies of teaching and learning of mathematical modelling in Antenna Theory and Design (ATD), using the interactive methods, as suggested by the University during COVID-19 period. In view of this, the paper confirms that the adoption of an interactive teaching and learning method helps to increase students’ understanding when learning ATD. In achieving the goal of the study, a qualitative style of data collection was adopted, coupled with a thematic approach of discussion of the study. This gives room for the appropriate approach of teaching and learning of mathematical modelling, in ATD courses, during COVID-19 era in a university in South Africa.
R&D and Development Dilemma: Analysis of Japanese Electronics Industry
Authors: Zhang Xiaohan
Published: January 2025

We study the factors which affect the Japanese economy stagnation. Using gross output data of Manufacturing from 1990 to 2015, we found among the top 10 industries, Machinery and equipment, Electrical, electronic and optical equipment, and Computer, electronic and optical products, these three industries which have negative growth are related to the GDP. We also find the R&D investment is related to the gross output in three industries. We argue that electronics industry’s decay is the reason of Japanese economy stagnation. One important reason of the dilemma in electronics industry is the stagnation of R&D investment, which shows business enterprises’ faith could be damaged for a long time.
Research on the Output Value of Broiler Industry
Authors: Zhang Jingyu
Published: January 2025

In recent years, the government has continuously increased the capital investment in broiler industry, aiming to promote the high-quality development of broiler industry. Under the guidance of the government's lead, the social capital has also been gradually invested in broiler industry, and the research on the production value of broiler industry in the economic field of broiler industry provides a realistic reference basis for the development of broiler industry. Grey correlation analysis is an important method to analyse the influencing factors of broiler industry output value, and it provides a theoretical basis for the study of broiler industry output value by establishing mathematical models to analyse the output value of broiler industry under different scale farming modes. Based on the relevant data of broiler industry in Henan Province from 2013 to 2022, this study uses grey correlation analysis method to select seven factors affecting broiler production value: litter fee, labour cost, medical and epidemic prevention fee, concentrate feed fee, fuel and power fee, death loss fee and fixed asset depreciation fee as comparison sequence, and per 100 broilers' production value as reference sequence, to calculate the degree to which the production value of broilers in large-scale farming is affected by the impacts of various influencing factors. The degree of influence by various influencing factors is calculated. The calculation results show that the broiler output value under small-scale farming conditions is mainly affected by depreciation of fixed assets (0.8528), death loss cost (0.7903) and fuel and power cost (0.7671), and the broiler output value under medium-scale farming conditions is mainly affected by depreciation of fixed assets (0.8798), medical and epidemic prevention cost (0.8457), death loss cost ( 0.8433), and broiler production value under large-scale farming conditions was mainly affected by fixed asset depreciation (0.8335), labour cost (0.8203), and fuel and power (0.8155), and fixed asset depreciation was an important factor affecting the production value of broilers in small-, medium- and large-scale farming at the same time.
Comparison and Experience of Housing Policies between China and Singapore
Authors: Wang Yiwen
Published: January 2025

The housing issue is a problem facing many countries and is very critical to the people. The Habitat Agenda adopted by the Second Conference on Human Settlements of the United Nations Human Settlements Programme in 1996 puts forward efforts to achieve the goal of "adequate housing for all", which shows the importance of the housing issue for the people. The two nature of housing policy, market and people's livelihood, is an important support to promote the urbanization process and the healthy development of the housing market, and is also an important method for governments to deal with the housing problem, promote people's well-being and maintain social stability. The issue of housing security in China has always been a hot topic of public concern, and is also one of the important people's livelihood issues that the government strives to solve. China's housing prices have always been very high, and the middle and low income groups are facing great pressure to buy homes. In contrast, Singapore has successfully solved the problem of housing supply for different income groups in the society. Studying the successful experience of Singapore's housing security system has important reference significance for improving China's housing security system. The dual nature of housing policy leads to the complexity of government intervention in housing market. On the one hand, the real estate industry is an important pillar to promote economic growth; On the other hand, housing insurance must meet the basic housing and survival needs of the public. This paper makes a comparative study of China and Singapore to solve the housing problem, and explores how China can learn from Singapore's experience to better solve the problem.
Clinical Experience of Yan Changhong in the Treatment of Herpes Zoster by Modified Da Qing Ye Tang with Bloodletting and Cupping at the Ashi Acupoint
Authors: He Yuxuan , Zhao Tenglu , Yan Changhong
Published: January 2025

Prof. Yan Changhong has been practicing medicine for dozens of years, with rich clinical experience, and specialized in the treatment of herpes zoster (HZ) using traditional Chinese medicine (TCM) therapy with obvious clinical effects. He believes that "poison" "fire" "dampness" "deficiency" and "blood stasis" are the main causes of HZ, and that clearing heat and removing toxins, strengthening the spleen and resolving dampness, and benefiting the vital energy and nourishing the blood are the main therapeutic methods of HZ. This article will summarize the clinical experience of Prof. Yan Changhong in the treatment of HZ by using modified Da Qing Ye Tang, acupuncture and bloodletting therapy at Ashi point combined with cupping, which is aimed at providing a new way of thinking for the treatment of HZ.
Research on Digital Technology Empowering the Teaching of "Modern Chinese" Course
Authors: Li Jinfeng , Chen Aixiang
Published: January 2025

Empowering higher education curriculum teaching with digital technology is an important way to promote high-quality development of higher education in the new era. This paper analyzes the connotation and implementation path of digital technology empowering the course of Modern Chinese. It mainly starts from three aspects: course content, teaching mode, and evaluation methods. The course teaching content is reconstructed into two parts: main knowledge and supplementary knowledge. The teaching mode of online and offline integration, theoretical and practical integration, and ideological and political element integration is implemented, promoting the transformation of teaching evaluation from a normal credit system to a diversified teaching evaluation system, promoting the deep integration of digital technology and course teaching, and realizing the dynamic and sustainable development of digital technology empowering higher education courses.
Maxwell's Equations and Four Dimensions
Authors: Chattopadhyay Rabindranath
Published: January 2025

Maxwell equations is viewed under the 4th dimension Ct. Not with t as an evolution of events seen by Mikowski, but with τ of Planck’s inside in 1900. In other words, Cτ as proposed by the Autor in his theory of space in 2021, i.e. the 4th longitudinal dimension lambda; energy´s wavelength Cτ.
The Relationship between Front Flip Movements on the Gymnastics Balance Beam and the Selection of Movement Variables
Authors: Jain Itisha , Caritativo Christian
Published: January 2025

Gymnasts are expected to demonstrate with beauty and flair. They should keep their body in the perfect position. Performance on beam started with mount and dismount considered to be as salto. This study aim was to find out the relationship between selected kinematic variables with the performance of forward turn over on balance beam in women artistic gymnastics. Five female gymnasts of Lakshmibai National Institute of physical education, Gwalior from the gymnastics match practice group, who had a good command in the particular skill (forward turn over on balance beam), were selected as the subject for the present study. . The video camera was placed perpendicularly at centre in the line of inner bar and parallel to the sagittal plane at a distance of 6mts and height of 2.10mt. Performance were evaluated by three judges on set criteria. Pearson product moment correlation was applied at 0.05 level of significance. There was a significant correlation between the angle at hip and the forward turn over performance of the gymnasts at landing phase only. The radius of rotation is likely to increase because increase in moment of inertia(I) which results decrease in angular velocity and helps the body to remain in linear velocity at landing phase as late as possible.