bluuebunny/crossref_metadata_2025 huggingface dataset:
Engaging English language learners with critical global literacies during the pull‐out: Instructional framework
Authors: Yol Özge , Yoon Bogum
Published: June 2019

Critical practices for promoting English language learners’ global and multicultural perspectives become more important in this global and interconnected world operating under systems of power, ideology, and hegemony. Grounded in the theoretical framework of critical global literacies and its explicit connection to pedagogy, the purposes of this qualitative case study with three middle school English language learners are (1) to introduce instructional practices to promote critical global literacies in English as a second language (ESL) classrooms and (2) to discuss how English language learners respond to these critical practices in a middle schoolESLpull‐out setting. This article highlights the findings of the students’ engagement through their actual voices and responses to the classroom activities. These findings challenge the preconceived notion that critical practices might be daunting to implement with English language learners. The findings also provide implications and practical suggestions on how to support students’ language and literacy learning through the process of empowerment as socially and globally oriented individuals in this ever‐changing, interconnected world.
Implications of the DRIVE Model of Reading: Making the Complexity of Reading Actionable
Authors: Duke Nell K. , Cartwright Kelly B.
Published: June 2019

This department highlights literacy leaders across the globe who are working in the field of literacy education. It features a variety of invited authors whose work is timely and relevant to the theme of access.
Who are the most inclined to learn? Evidence from Chinese multinationals’ internationalization in the European Union
Authors: Chen Liang , Li Yi , Fan Di
Published: June 2019

While it is widely recognised that an asset-augmenting rather than asset-exploiting strategy drives emerging multinationals’ (EMNEs) internationalization, current research focuses on the motivations behind knowledge seeking FDI. What remains less clear is why latecomer firms can engage in learning in advanced countries. Conjoining the “Linkage-Leverage-Learning (LLL)” framework and knowledge seeking literature, this study shows how Chinese investment in the European Union reveals the preconditions for foreign knowledge sourcing. We follow a set-theoretic approach, utilizing fuzzy-set qualitative comparative analysis (fsQCA), to identify equifinal configurations of linkage and leverage conditions leading to high learning propensity of EMNEs. Our analysis extends the LLL framework and complements the recent debate on the theory of the EMNE. We develop propositions based on distinct constellations of learning antecedents.
Impact of Weather and Herd Size Management on Beef Cow Profitability
Authors: Tester Colson A. , Popp Michael P. , Kemper Nathan P. , Nalley Lanier L. , West Grant
Published: June 2019

Producers often contemplate expanding or contracting production to take advantage of cyclical cattle price trends. This study quantifies profitability and risk implications of (1) constant herd size, (2) dollar cost averaging, and (3) price signal-based, anticipatory countercyclical expansion/contraction strategies. Weather simulation on forages with different calving season and land use intensity showed fall calving herds with added hay sales from greater fertilizer use and the countercyclical herd size management strategy to be most profitable regardless of weather or time period analyzed. Income risk was comparable to least fertilizer use. Overall, holding herd size constant led to little regret.
Work and Discipline on the East African Coast
Authors: White Luise
Published: June 2019

Frederick Cooper’s first three books, published between 1977 and 1987, were written during African historians’ first sustained critical engagement with African archives and African voices. Cooper’s books were literally in the weeds with slave and free labor in East Africa, yet their importance went beyond the region. Read in sequence, we see how Cooper’s work was shifting toward studies of the metropole by the mid-1980s. Taken together we see how practices in the workplace shaped policies in Whitehall, that conditions on plantations and on docks caused a rethinking of how colonialists might most successfully exert control.
Jam v. International Finance Corp. (U.S. Sup. Ct.)
Authors: Perkins Nancy , Pei Sally
Published: June 2019

On February 27, 2019, the U.S. Supreme Court issued an opinion in Jam v. International Finance Corp., a case of critical importance for international organizations. The question presented in Jam was whether U.S. law affords international organizations absolute immunity from suit in the United States, or whether international organizations instead are entitled to only the more limited or “restrictive” immunity that applies to foreign sovereigns under the Foreign Sovereign Immunities Act.
A framework for input–output analysis of wall-bounded shear flows
Authors: Ahmadi Mohamadreza , Valmorbida Giorgio , Gayme Dennice , Papachristodoulou Antonis
Published: June 2019

We propose a new framework to evaluate input–output amplification properties of nonlinear models of wall-bounded shear flows, subject to both square integrable and persistent disturbances. We focus on flows that are spatially invariant in one direction and whose base flow can be described by a polynomial, e.g. streamwise-constant channel, Couette and pipe flows. Our methodology is based on the notion of dissipation inequalities in control theory and provides a single unified approach for examining flow properties such as energy growth, worst-case disturbance amplification and stability to persistent excitations (i.e. input-to-state stability). It also enables direct analysis of the nonlinear partial differential equation rather than of a discretized form of the equations, thereby removing the possibility of truncation errors. We demonstrate how to numerically compute the input–output properties of the flow as the solution of a (convex) optimization problem. We apply our theoretical and computational tools to plane Couette, channel and pipe flows. Our results demonstrate that the proposed framework leads to results that are consistent with theoretical and experimental amplification scalings obtained in the literature.
Mixing and entrainment are suppressed in inclined gravity currents
Authors: van Reeuwijk Maarten , Holzner Markus , Caulfield C. P.
Published: June 2019

We explore the dynamics of inclined temporal gravity currents using direct numerical simulation, and find that the current creates an environment in which the flux Richardson number $\mathit{Ri}_{f}$, gradient Richardson number $\mathit{Ri}_{g}$ and turbulent flux coefficient $\unicode[STIX]{x1D6E4}$ are constant across a large portion of the depth. Changing the slope angle $\unicode[STIX]{x1D6FC}$ modifies these mixing parameters, and the flow approaches a maximum Richardson number $\mathit{Ri}_{max}\approx 0.15$ as $\unicode[STIX]{x1D6FC}\rightarrow 0$ at which the entrainment coefficient $E\rightarrow 0$. The turbulent Prandtl number remains $O(1)$ for all slope angles, demonstrating that $E\rightarrow 0$ is not caused by a switch-off of the turbulent buoyancy flux as conjectured by Ellison (J. Fluid Mech., vol. 2, 1957, pp. 456–466). Instead, $E\rightarrow 0$ occurs as the result of the turbulence intensity going to zero as $\unicode[STIX]{x1D6FC}\rightarrow 0$, due to the flow requiring larger and larger shear to maintain the same level of turbulence. We develop an approximate model valid for small $\unicode[STIX]{x1D6FC}$ which is able to predict accurately $\mathit{Ri}_{f}$, $\mathit{Ri}_{g}$ and $\unicode[STIX]{x1D6E4}$ as a function of $\unicode[STIX]{x1D6FC}$ and their maximum attainable values. The model predicts an entrainment law of the form $E=0.31(\mathit{Ri}_{max}-\mathit{Ri})$, which is in good agreement with the simulation data. The simulations and model presented here contribute to a growing body of evidence that an approach to a marginally or critically stable, relatively weakly stratified equilibrium for stratified shear flows may well be a generic property of turbulent stratified flows.
Relative periodic solutions in conducting liquid films flowing down vertical fibres
Authors: Ding Zijing , Willis Ashley P.
Published: June 2019

The dynamics of a conducting liquid film flowing down a cylindrical fibre, subjected to a radial electric field, is investigated using a long-wave model (Ding et al., J. Fluid Mech., vol. 752, 2014, p. 66). In this study, to account for the complicated interactions between droplets, we consider two large droplets in a periodic computational domain and find two distinct types of travelling wave solutions, which consist of either two identical droplets (type I) or two slightly different droplets (type II). Both are ‘relative’ equilibria, i.e. steady in a frame moving at their phase speed, and are stable in smaller domains when the electric field is weak. We also study relative periodic orbits, i.e. temporally recurrent dynamic solutions of the system. In the presence of the electric field, we show how these invariant solutions are linked to the dynamics, where the system can evolve into one of the steady travelling wave states, into an oscillatory state, or into a ‘singular structure’ (Wray et al., J. Fluid Mech., vol. 735, 2013, pp. 427–456; Ding et al., J. Fluid Mech., vol. 752, 2014, p. 66). We find that the oscillation between two similarly sized large droplets in the oscillatory state is well represented by relative periodic orbits. Varying the electric field strength, we demonstrate that relative periodic solutions arise as the dynamically important solution once the type-I or type-II travelling wave solutions lose stability. Oscillation can be either enhanced or impeded as the electric field’s strength increases. When the electric field is strong, no relative periodic solutions are found and a spike-like singular structure is observed. For the case where the electric field is not present, the oscillation is instead caused by the interaction between a large droplet and a nearby much smaller droplet. We show that this oscillation phenomenon originates from the instability of the type-I travelling wave solution in larger domains, and that the oscillatory state can again be represented by an exact relative periodic orbit. The relative periodic orbit solution is also compared with experimental study for this case. The present study demonstrates that the relative periodic solutions are better at capturing the wave speed and oscillatory dynamics than the travelling wave solutions in the unsteady flow regime.
Iron Age landscape changes in the Benoué River Valley, Cameroon
Authors: Wright David K. , MacEachern Scott , Ambrose Stanley H. , Choi Jungyu , Choi Jeong-Heon , Lang Carol , Wang Hong
Published: June 2019

The introduction of agriculture is known to have profoundly affected the ecological complexion of landscapes. In this study, a rapid transition from C3to C4vegetation is inferred from a shift to higher stable carbon (13C/12C) isotope ratios of soils and sediments in the Benoué River Valley and upland Fali Mountains in northern Cameroon. Landscape change is viewed from the perspective of two settlement mounds and adjacent floodplains, as well as a rock terrace agricultural field dating from 1100 cal yr BP to the recent past (<400 cal yr BP). Nitrogen (15N/14N) isotope ratios and soil micromorphology demonstrate variable uses of land adjacent to the mound sites. These results indicate that Early Iron Age settlement practices involved exploitation of C3plants on soils with low δ15N values, indicating wetter soils. Conversely, from the Late Iron Age (>700 cal yr BP) until recent times, high soil and sediment δ13C and δ15N values reflect more C4biomass and anthropogenic organic matter in open, dry environments. The results suggest that Iron Age settlement practices profoundly changed landscapes in this part of West Africa through land clearance and/or utilization of C4plants.
Disgruntled Elites and Imperial States: The Making of Late Nineteenth- and Early Twentieth-Century Civil Society in Congress Poland and Western Galicia.
Authors: Kurjanska Malgorzata
Published: June 2019

Why does civil society in some cases become a tool of elite organization and domination of non-elites, and in others a sphere for non-elite self-organization and self-determination? To answer this question, this article compares the late nineteenth- and early twentieth-century divergent developments of civil society in two regions of the former Polish-Lithuanian Commonwealth: Russian-ruled Congress Poland, with a focus on the Warsaw Governorate (1815–1915), and Austrian-ruled western-Galicia, concentrating on the Grand Duchy of Krakow (1846–1914). This analysis of variation in elite domination of civil society shifts the focus of civil society debates away from the market and the state and toward elites. It argues that while imperial policies of regional integration and socioeconomic changes spurred by the transition from feudalism shaped the potential paths of civil society's development in both regions, their effects on civil society's relative autonomy in each were mediated, and thus steered, by the interests and conflicts of local elites.
Rival Mission, Rival Science? Jesuits and Pietists in Seventeenth- and Eighteenth-Century South India
Authors: Sweetman Will , Županov Ines G.
Published: June 2019

Two European missionary teams, one Catholic and the other Protestant, encountered each other in the Tamil country in the first decade of the eighteenth century. They acted as if and thought that their goals were irreconcilable, even if the Protestants in Tranquebar admitted that the Catholic Jesuit proselytism in the region had been efficient as “preparatio evangelicae” for the Protestant mission. Jesuits and Pietists were not only rivals; they also collaborated, uneasily and unequally, in collecting, processing, and disseminating knowledge. Missionary linguistic and medico-botanical expertise was considered an indispensable proselytizing tool, and it showcased their “scientific” achievements that were admired and envied in Europe. Both Pietists and Jesuits of this period were fighting the early Enlightenment atheists while feeding them the materials from the missions. Both missionary groups were also victims of Enlightenment historiography. Despite their theological differences, they were far closer in their practices than either the missionaries themselves or their historians, who have mostly written from the same denominational perspective, have been willing to acknowledge. In part this was because the Protestants, especially their mission's founders, relied on both texts and converts produced by their Catholic rivals.
Making Communism Work: Sinicizing a Soviet Governance Practice
Authors: Perry Elizabeth J.
Published: June 2019

Among various grassroots governance practices adopted by the Chinese Communist Party (CCP), few have proven more adaptive and effective than the deployment of work teams—ad hoc units appointed and directed by higher-level Party and government organs and dispatched for a limited time to carry out a specific mission by means of mass mobilization. Yet, perhaps because work teams straddle the boundary between formal and informal institutions, they have received scant analytical attention. While work teams figure prominently in narrative accounts of the major campaigns of Mao's China, their origins, operations, and contemporary implications have yet to be fully explored. This article traces the roots of Chinese work teams to Russian revolutionary precedents, including plenipotentiaries, shock brigades, and 25,000ers, but argues that the CCP's adoption and enhancement of this practice involved creative adaptation over a sustained period of revolutionary and post-revolutionary experimentation. Sinicized work teams were not only a key factor in securing the victory of the Chinese Communist revolution and conducting Maoist mass campaigns such as Land Reform, Collectivization, and the Four Cleans; they continue to play an important role in the development and control of grassroots Chinese society even today. As a flexible means of spanning the center-periphery divide and combatting bureaucratic inertia, Chinese work teams, in contrast to their Soviet precursors, contribute to the resilience of the Communist party-state.
Democratic Socialism in Chile and Peru: Revisiting the “Chicago Boys” as the Origin of Neoliberalism
Authors: Bockman Johanna
Published: June 2019

In the 1950s and 1960s, the U.S. government paid the economics department at the University of Chicago, known for its advocacy of free markets and monetarism, to train Chilean graduate students. These students became known as the “Chicago Boys,” who implemented the first and most famous neoliberal experiment in Chile after 1973. Peruvian, Mexican, and other Latin American economics students followed a similar path and advocated a turn to neoliberal policies in their own countries. The Chicago Boys narrative has become an origin story for global neoliberalism. However, the focus on this narrative has obscured other transnational networks whose ideas possess certain superficial, but misleading, similarities with neoliberalism. I examine Chilean and Peruvian engagements with Yugoslavia's unique form of socialism, its worker self-management socialism, which was part of a worldwide discussion of anti-authoritarian socialism. I first introduce the Yugoslav socialist model that inspired those in Chile and Peru. I then examine socialist discussions in Chile and Peru that called for decentralized, democratic socialism and looked to Yugoslavia for advice. I conclude by examining the 1990s postponement of socialism in the name of a very narrow democracy and realization of neoliberalism. The Chicago Boys story assumes the easy global victory of neoliberalism and erases what was at stake in the 1988–1994 period: radically democratic socialism on a global scale.
Ocular spirorchiidiosis in sea turtles from Brazil
Authors: Jerdy H. , Werneck M. , Goldberg D. , Baldassin P. , Feriolli R. , Maranho A. , Ribeiro R. , Bianchi M. , Ribeiro L. , Shimoda E. , Carvalho E.
Published: June 2019

The causes of the beaching and death of sea turtles have not been fully clarified and continue to be studied. Mild, moderate and severe lesions caused by spirorchiidiosis have been seen for decades in different organs and were recently defined as the cause of death of a loggerhead turtle. In the present study, eyes and optic nerves were analysed in green sea turtles with spirorchiidiosis and no other debilitating factors. Injuries to the optic nerve and choroid layer were described in 235 animals (90%) infected with spirorchiids. Turtles with ocular spirorchiidiosis are approximately three times more likely to be cachectic than turtles with spirorchiidiosis without ocular involvement.
Influence of an extreme climatic event on bilateral asymmetry and occurrence of eye flukes in perch (Perca fluviatilis) and roach (Rutilus rutilus) from a lake in southeast England
Authors: Morley N.J. , Lewis J.W.
Published: June 2019

Eye flukes are common infections of freshwater fish and their occurrence as metacercarial stages may occur non-randomly resulting in an asymmetrical distribution within the host eyes. However, from previous studies the presentation of bias by these trematodes lacks consistency suggesting that congenital asymmetrical effects are unlikely to be the cause and exogenous factors, such as environmental stress, may be more influential. The present study, undertaken over a 4-year period, investigates the impact of an extreme heatwave and drought on the annual bilateral asymmetry and occurrence of two eye fluke species (Diplostomum sp. in the lens and Tylodelphys sp. in the vitreous humour) from perch (Perca fluviatilis) and roach (Rutilus rutilus). The onset of the extreme climatic event resulted in a significant negative effect on the occurrence of the eye flukes. Bilateral asymmetry, which was present within both trematode species and hosts, appeared to be highly variable between eye fluke and fish species and also year of study. However, during the pre-drought period both host species demonstrated significant asymmetry for Tylodelphys sp. but not for Diplostomum sp. while during the drought this bias was reversed. The potential role of fluctuating asymmetry of fish hosts in structuring the bilateral asymmetry of eye flukes is discussed.
Comparative evaluation of round window niche accessibility pre-operatively on high-resolution computed tomography of the temporal bone with intra-operative findings
Authors: Sharma R , Meher R , Passey J C , Kumar J , Gupta A , Kharbanda S
Published: June 2019

Objective

To compare round window niche visibility as seen endoscopically during cochlear implant surgery with pre-operative high-resolution computed tomography of the temporal bone.

Methods

Nineteen patients scheduled for cochlear implantation, aged 2–20 years, were referred for computed tomography from October 2016 to March 2018. Angles were measured between the lines passing through the mid-sagittal plane and cochlear basal turn on the scans. Endoscopic round window niche visibility during posterior tympanotomy was categorised as: type I = 100 per cent, type IIa = more than 50 per cent, type IIb = less than 50 per cent or type III = 0 per cent. Pre-operative computed tomography measurements were used to predict round window niche visibility before surgery and correlated with intra-operative findings.

Results

The mean (range) of pre-operative angles on computed tomography for endoscopic visibility types I, IIa and IIb, were 64.06° (61.16–69.37°), 63.81° (58.61–71.35°) and 56.48° (50.37–59.05°), respectively, a statistically significant finding (one-way analysis of variance test, p = 0.016).

Conclusion

Pre-operative high-resolution temporal bone computed tomography measurements are useful in predicting round window niche visualisation as viewed endoscopically during posterior tympanotomy. The angle was more acute in type IIb compared to type I.
An unusual case of concordant ventriculoarterial connections, subpulmonary infundibulum, and parallel arterial trunks: a diagnostic challenge
Authors: Nelson James A. , Soriano Brian D. , Buddhe Sujatha
Published: June 2019

We present an unusual case of concordant ventriculoarterial connections, subpulmonary infundibulum, and parallel arterial trunks. This case was complicated by extreme pulmonary artery tortuosity and low arching aorta causing severe tracheal compression. We discuss the difficulty in prenatal diagnosis, necessity for advanced imaging postnatally, and associated airway complications.
Anomalous single trunk coronary artery from the right pulmonary artery
Authors: Donmez Yasemin Nuran , Aykan Hayrettin Hakan , Yilmaz Mustafa
Published: June 2019

Anomalous single coronary artery from pulmonary artery is a very rare congenital heart anomaly. Anomalous single coronary artery from pulmonary artery has high mortality rates and poor surgical outcome despite advanced surgical techniques. We report a 4-month-old infant presented by congestive heart failure findings and diagnosed with anomalous single trunk coronary arteries arising from right pulmonary artery.
Early conversion of classic Fontan conversion may decrease term morbidity: single centre outcomes
Authors: Blitzer David , Habib Asma S. , Brown John W. , Kean Adam C. , Lin Jiuann-Huey I. , Turrentine Mark W. , Rodefeld Mark D. , Herrmann Jeremy L. , Kay William Aaron
Published: June 2019

Background:

The initial classic Fontan utilising a direct right atrial appendage to pulmonary artery anastomosis led to numerous complications. Adults with such complications may benefit from conversion to a total cavo-pulmonary connection, the current standard palliation for children with univentricular hearts.

Methods:

A single institution, retrospective chart review was conducted for all Fontan conversion procedures performed from July, 1999 through January, 2017. Variables analysed included age, sex, reason for Fontan conversion, age at Fontan conversion, and early mortality or heart transplant within 1 year after Fontan conversion.

Results:

A total of 41 Fontan conversion patients were identified. Average age at Fontan conversion was 24.5 ± 9.2 years. Dominant left ventricular physiology was present in 37/41 (90.2%) patients. Right-sided heart failure occurred in 39/41 (95.1%) patients and right atrial dilation was present in 33/41 (80.5%) patients. The most common causes for Fontan conversion included atrial arrhythmia in 37/41 (90.2%), NYHA class II HF or greater in 31/41 (75.6%), ventricular dysfunction in 23/41 (56.1%), and cirrhosis or fibrosis in 7/41 (17.1%) patients. Median post-surgical follow-up was 6.2 ± 4.9 years. Survival rates at 30 days, 1 year, and greater than 1-year post-Fontan conversion were 95.1, 92.7, and 87.8%, respectively. Two patients underwent heart transplant: the first within 1 year of Fontan conversion for heart failure and the second at 5.3 years for liver failure.

Conclusions:

Fontan conversion should be considered early when atrial arrhythmias become common rather than waiting for severe heart failure to ensue, and Fontan conversion can be accomplished with an acceptable risk profile.
Keeping up with the clinical advances: depression
Authors: Ragguett Renee-Marie , Tamura Jocelyn K. , McIntyre Roger S.
Published: June 2019

Major depressive disorder (MDD) is a prevalent and heterogeneous disorder. Although there are many treatment options for MDD, patients with treatment-resistant depression (TRD) remain prevalent, wherein delayed time to response results in inferior chances of achieving remission. Recently, therapeutics have been developed that depart from the traditional monoamine hypothesis of depression and focus instead on the glutamatergic, GABAergic, opioidergic, and inflammatory systems. The literature suggests that the foregoing systems are implicated in the pathophysiology of MDD and preclinical trials have informed the development of pharmaceuticals using these systems as therapeutic targets. Pharmaceuticals that target the glutamatergic system include ketamine, esketamine, and rapastinel; brexanolone and SAGE-217 target the GABAergic system; minocycline targets the inflammatory system; and the combinatory agent buprenorphine + samidorphan targets the opioidergic system. The aforementioned agents have shown efficacy in treating MDD in clinical trials. Of particular clinical relevance are those agents targeting the glutamatergic and GABAergic systems as they exhibit rapid response relative to conventional antidepressants. Rapid response pharmaceuticals have the potential to transform the treatment of MDD, demonstrating reduction in depressive symptoms within 24 hours, as opposed to weeks noted with conventional antidepressants. Novel therapeutics have the potential to improve both patient mood symptomatology and economical productivity, reducing the debased human capital costs associated with MDD. Furthermore, a selection of therapeutic targets provides diverse treatment options which may be beneficial to the patient considering the heterogeneity of MDD.
The ‘Merits of Isfahan’ from Arabic into Persian
Authors: MARLOW LOUISE
Published: June 2019

Writing in Isfahan in 729/1328-9, Ḥusayn b. Muḥammad b. Abī l-Riżā ʿAlavī Āvī produced a translation into Persian of the eleventh-century Arabic Risālat Maḥāsin Iṣfahān (‘Epistle on the Merits of Isfahan’) of Mufaḍḍal b. Saʿd b. al-Ḥusayn al-Māfarrukhī. This article explores the context for and purposes of Āvī’s translation-adaptation with particular reference to the extensive system of networks active in western Iran during the reign of the Ilkhan Abū Saʿīd (r. 716-36/1316-35). It is proposed that Āvī intended his translation to provide a means of entry into the urban élites and an affiliation with the administrative circles associated with the vizier Ghiyāth al-Dīn Muḥammad (d. 736/1336), a son of Rashīd al-Dīn Fażl Allāh, who occupied a position at the apex of this system of networks.
Personnel is Policy: Regulatory Capture at the Federal Trade Commission, 1914–1929
Authors: Newman Patrick
Published: June 2019

This paper uses the concept of “Personnel is Policy” to extend the theory of regulatory capture to the political appointment of agency commissioners. The “Personnel is Policy” theory provides three important insights. First, it shows that whether or not an interest group benefits from a regulatory agency depends on the particular individuals appointed to run it. Second, the president plays an important role in regulatory capture by nominating individuals to be appointed to the commission. Third, regulatory capture does not follow a pre-determined path because the commissioners continually change. The theory is then used to explain the early years of a prominent regulatory agency created during the Progressive Era: the Federal Trade Commission. From the perspective of the big business “trust” interest group, their success at capturing the FTC to achieve their goals of controlling competition and blocking hostile antitrust actions was largely a result of who was appointed to the commission. The trusts were the most successful during the years of 1915–1916 and 1925–1929.
A Massive Slump on the St. Pierre Slope, A New Perspective on the 1929 Grand Banks Submarine Landslide
Authors: Schulten Irena , Mosher David C. , Piper David J. W. , Krastel Sebastian
Published: June 2019

The 1929 Grand Banks submarine landslide on the southwestern Grand Banks of Newfoundland was triggered by a Mw 7.2 strike‐slip earthquake. It is the first studied example of a submarine mass movement known to have caused a turbidity current and tsunami. The event resulted in 28 casualties and caused severe economic damage. The St. Pierre Slope is the main source area for the sediment failure. It contains translational and probable retrogressive surficial failures (<25 m); the majority of which lie in >1,700‐m water depth. These observations contradict what might be expected for a tsunamigenic event; thus, the objective of this study is to look for other potential causal mechanisms. A comprehensive analysis of 2‐D seismic reflection data of various resolutions and multibeam bathymetry allowed mapping of new stratigraphic and structural features. Numerous, low‐angle (~17°) faults are present throughout the Quaternary section of the St. Pierre Slope that are associated with seafloor escarpments (750‐ to 2,000‐m water depth). These faults have up to 100‐m high displacement and are interpreted as part of a massive (~560 km3), complex slump. There are multiple décollements (250‐ and 400‐ to 550‐m below seafloor) within this slump and there is indication for slumping in at least two directions. Evidence suggests slumping as a result of the 1929 earthquake occurred along these faults, with ~100‐m seafloor displacement in places. The 1929 submarine landslide therefore involved two failure mechanisms: massive slumping (~500‐m thick) and consequent widespread, surficial (<25 m) sediment failure. Both failure mechanisms likely contributed to tsunami generation.
The Impact of Waves and Tides on Residual Sand Transport on a Sediment‐Poor, Energetic, and Macrotidal Continental Shelf
Authors: King E. V. , Conley D. C. , Masselink G. , Leonardi N. , McCarroll R. J. , Scott T.
Published: June 2019

The energetic, macrotidal shelf off South West England was used to investigate the influence of different tide and wave conditions and their interactions on regional sand transport patterns using a coupled hydrodynamic, wave, and sediment transport model. Residual currents and sediment transport patterns are important for the transport and distribution of littoral and shelf‐sea sediments, morphological evolution of the coastal and inner continental shelf zones, and coastal planning. Waves heavily influence sand transport across this macrotidal environment. Median (50% exceedance) waves enhance transport in the tidal direction. Extreme (1% exceedance) waves can reverse the dominant transport path, shift the dominant transport phase from flood to ebb, and activate sand transport below 120‐m depth. Wave‐tide interactions (encompassing radiation stresses, Stoke's drift, enhanced bottom‐friction and bed shear stress, refraction, current‐induced Doppler shift, and wave blocking) significantly and nonlinearly enhance sand transport, determined by differencing transport between coupled, wave‐only, and tide‐only simulations. A new continental shelf classification scheme is presented based on sand transport magnitude due to wave‐forcing, tide‐forcing, and nonlinear wave‐tide interactions. Classification changes between different wave/tide conditions have implications for sand transport direction and distribution across the shelf. Nonlinear interactions dominate sand transport during extreme waves at springs across most of this macrotidal shelf. At neaps, nonlinear interactions drive a significant proportion of sand transport under median and extreme waves despite negligible tide‐induced transport. This emphasizes the critical need to consider wave‐tide interactions when considering sand transport in energetic environments globally, where previously tides alone or uncoupled waves have been considered.
Ambiguity in the Land Use Component of Mitigation Contributions Toward the Paris Agreement Goals
Authors: Fyson C. L. , Jeffery M. L.
Published: June 2019

Land use, land use change, and forestry (LULUCF) activities, including deforestation and forest restoration, will play an important role in addressing climate change. Countries have stated their contributions to reducing emissions and enhancing sinks in their Nationally Determined Contributions (NDCs); in 2023, the Global Stocktake will assess the collective impact of these NDCs. Clarity in the contribution of LULUCF to NDC targets is necessary to prevent high LULUCF uncertainties from undermining the strength and clarity of mitigation in other sectors. We assess and categorize all 167 NDCs and find wide variation in how they incorporate LULUCF; many lack the clear information necessary to understand what land‐based mitigation is anticipated. The land sector is included in 121 NDCs, but only 11 provide a LULUCF target that can be fully quantified using information presented or referenced in the NDC. By developing alternative scenarios from a subset of 62 NDCs (89 countries), we estimate that ambiguity in LULUCF contributions causes an uncertainty range in the anticipated LULUCF sink in 2030 of magnitude 2.9 GtCO2eq/year—larger in size than our best estimate for the LULUCF sink of −2 GtCO2eq/year. Clearer communication of data sources and assumptions underlying the contribution of land use to mitigation efforts is therefore important for ensuring a robust Global Stocktake and ambitious emissions reductions. We find that guidance under the Paris Agreement may improve the clarity of future NDCs but is not sufficient to eliminate ambiguities. We therefore recommend that LULUCF targets should be presented and accounted for separately from other sectors.
Stream‐Discharge Surges Generated by Groundwater Flow
Authors: Guérin Adrien , Devauchelle Olivier , Robert Vincent , Kitou Thierry , Dessert Céline , Quiquerez Amélie , Allemand Pascal , Lajeunesse Eric
Published: June 2019

Catchments respond to rainfall by storing and releasing water according to their internal dynamics. Groundwater had long been treated as the slow reservoir in this process, but isotopic measurements showed how responsive it can be. Here, we investigate the mechanics of groundwater's contribution to floods. To do so, we monitored over 3 years the shape of the water table in, and the runoff out of, a small tropical catchment. We find that groundwater and runoff respond within minutes of a rainfall event. Using an asymptotic theory inspired by recent laboratory experiments, we suggest that the peak water discharge at the catchment's outlet increases like the rainfall rate to the power of 3/2. This formula consistently predicts the stream's response to the 137 isolated rainfall events recorded during our field survey. In addition, its prefactor yields an estimate of the average groundwater storage.
Simulation of Prompt Acceleration of Radiation Belt Electrons During the 16 July 2017 Storm
Authors: Patel Maulik , Li Zhao , Hudson Mary , Claudepierre Seth , Wygant John
Published: June 2019

We investigate the prompt enhancement of radiation belt electron flux observed by the Relativistic Electron Proton Telescope instrument on board Van Allen Probes following the 16 July 2017 CME‐shock compression using MHD‐test particle simulations. The prompt enhancements can be explained by the source population interacting with the azimuthally directed electric field impulses induced by CME‐shock compressions of the dayside magnetopause. Electrons in drift resonance with the electric field impulse were accelerated by ∼ 0.6 MeV on a drift period timescale (in minutes) as the impulse propagated from the dayside to the nightside around the flanks of the magnetosphere. MHD test particle simulation of energization and drift phase bunching, due to the bipolar electric field that accompanies the dayside compression and relaxation, is found to be consistent with Van Allen Probes observations. This study reproduces the energy‐dependent drift echoes integrated over pitch angle and observed change in spectra for the first time.
A Persistent, Large‐Scale, and Ordered Electrodynamic Connection Between Saturn and Its Main Rings
Authors: Sulaiman A. H. , Farrell W. M. , Ye S.‐Y. , Kurth W. S. , Gurnett D. A. , Hospodarsky G. B. , Menietti J. D. , Píša D. , Hunt G. J. , Agiwal O. , Dougherty M. K.
Published: June 2019

Auroral hiss emissions are ubiquitous in planetary magnetospheres, particularly in regions where electric current systems are present. They are generally diagnostic of electrodynamic coupling between conductive bodies, thus making auroral and moon‐connected magnetic field lines prime locations for their detection. However, the role of Saturn's rings as a dynamic conductive body has been elusive and of great interest to the community. Cassini's Grand Finale orbits afforded a unique opportunity to directly sample magnetic field lines connected to the main rings. Here we provide strong evidence for the persistent and organized presence of auroral hiss demonstrably associated with the main rings. This is in contrast to recent observations suggesting that Saturn's rings may be barriers to field‐aligned currents. Our results provide a new view of Saturn's rings as a dynamic system that is in continuous and ordered electrodynamic coupling with the planet.
Acceleration of Ions in Jovian Plasmoids: Does Turbulence Play a Role?
Authors: Kronberg E. A. , Grigorenko E. E. , Malykhin A. , Kozak L. , Petrenko B. , Vogt M. F. , Roussos E. , Kollmann P. , Jackman C. M. , Kasahara S. , Malova Kh. V. , Tao C. , Radioti A. , Masters A.
Published: June 2019

The dissipation processes which transform electromagnetic energy into kinetic particle energy in space plasmas are still not fully understood. Of particular interest is the distribution of the dissipated energy among different species of charged particles. The Jovian magnetosphere is a unique laboratory to study this question because outflowing ions from the moon Io create a high diversity in ion species. In this work, we use multispecies ion observations and magnetic field measurements by the Galileo spacecraft. We limit our study to observations of plasmoids in the Jovian magnetotail, because there is strong ion acceleration in these structures. Our model predicts that electromagnetic turbulence in plasmoids plays an essential role in the acceleration of oxygen, sulfur, and hydrogen ions. The observations show a decrease of the oxygen and sulfur energy spectral index γ at ∼30 to ∼400 keV/nuc with the wave power indicating an energy transfer from electromagnetic waves to particles, in agreement with the model. The wave power threshold for effective acceleration is of the order of 10 nT2Hz−1, as in terrestrial plasmoids. However, this is not observed for hydrogen ions, implying that processes other than wave‐particle interaction are more important for the acceleration of these ions or that the time and energy resolution of the observations is too coarse. The results are expected to be confirmed by improved plasma measurements by the Juno spacecraft.
High Survivability of Micrometeorites on Mars: Sites With Enhanced Availability of Limiting Nutrients
Authors: Tomkins Andrew G. , Genge Matthew J. , Tait Alastair W. , Alkemade Sarah L. , Langendam Andrew D. , Perry Prudence P. , Wilson Sasha
Published: June 2019

NASA's strategy in exploring Mars has been to follow the water, because water is essential for life, and it has been found that there are many locations where there was once liquid water on the surface. Now perhaps, to narrow down the search for life on a barren basalt‐dominated surface, there needs to be a refocusing to a strategy of “follow the nutrients.” Here we model the entry of metallic micrometeoroids through the Martian atmosphere, and investigate variations in micrometeorite abundance at an analogue site on the Nullarbor Plain in Australia, to determine where the common limiting nutrients available in these (e.g., P, S, Fe) become concentrated on the surface of Mars. We find that dense micrometeorites are abundant in a range of desert environments, becoming concentrated by aeolian processes into specific sites that would be easily investigated by a robotic rover. Our modeling suggests that micrometeorites are currently far more abundant on the surface of Mars than on Earth, and given the far greater abundance of water and warmer conditions on Earth and thus much more active weather system, this was likely true throughout the history of Mars. Because micrometeorites contain a variety of redox sensitive minerals including FeNi alloys, sulfide and phosphide minerals, and organic compounds, the sites where these become concentrated are far more nutrient rich, and thus more compatible with chemolithotrophic life than most of the Martian surface.
Use and abuse of correlation analyses in microbial ecology
Authors: Carr Alex , Diener Christian , Baliga Nitin S , Gibbons Sean M
Published: June 2019

Correlation analyses are often included in bioinformatic pipelines as methods for inferring taxon–taxon interactions. In this perspective, we highlight the pitfalls of inferring interactions from covariance and suggest methods, study design considerations, and additional data types for improving high-throughput interaction inferences. We conclude that correlation, even when augmented by other data types, almost never provides reliable information on direct biotic interactions in real-world ecosystems. These bioinformatically inferred associations are useful for reducing the number of potential hypotheses that we might test, but will never preclude the necessity for experimental validation.
DNA requirement in FANCD2 deubiquitination by USP1-UAF1-RAD51AP1 in the Fanconi anemia DNA damage response
Authors: Liang Fengshan , Miller Adam S. , Longerich Simonne , Tang Caroline , Maranon David , Williamson Elizabeth A. , Hromas Robert , Wiese Claudia , Kupfer Gary M. , Sung Patrick
Published: June 2019

Fanconi anemia (FA) is a multigenic disease of bone marrow failure and cancer susceptibility stemming from a failure to remove DNA crosslinks and other chromosomal lesions. Within the FA DNA damage response pathway, DNA-dependent monoubiquitinaton of FANCD2 licenses downstream events, while timely FANCD2 deubiquitination serves to extinguish the response. Here, we show with reconstituted biochemical systems, which we developed, that efficient FANCD2 deubiquitination by the USP1-UAF1 complex is dependent on DNA and DNA binding by UAF1. Surprisingly, we find that the DNA binding activity of the UAF1-associated protein RAD51AP1 can substitute for that of UAF1 in FANCD2 deubiquitination in our biochemical system. We also reveal the importance of DNA binding by UAF1 and RAD51AP1 in FANCD2 deubiquitination in the cellular setting. Our results provide insights into a key step in the FA pathway and help define the multifaceted role of the USP1-UAF1-RAD51AP1 complex in DNA damage tolerance and genome repair.
Efficient base editing for multiple genes and loci in pigs using base editors
Authors: Xie Jingke , Ge Weikai , Li Nan , Liu Qishuai , Chen Fangbing , Yang Xiaoyu , Huang Xingyun , Ouyang Zhen , Zhang Quanjun , Zhao Yu , Liu Zhaoming , Gou Shixue , Wu Han , Lai Chengdan , Fan Nana , Jin Qin , Shi Hui , Liang Yanhui , Lan Ting , Quan Longquan , Li Xiaoping , Wang Kepin , Lai Liangxue
Published: June 2019

Cytosine base editors (CBEs) enable programmable C-to-T conversion without DNA double-stranded breaks and homology-directed repair in a variety of organisms, which exhibit great potential for agricultural and biomedical applications. However, all reported cases only involved C-to-T substitution at a single targeted genomic site. Whether C-to-T substitution is effective in multiple sites/loci has not been verified in large animals. Here, by using pigs, an important animal for agriculture and biomedicine, as the subjective animal, we showed that CBEs could efficiently induce C-to-T conversions at multiple sites/loci with the combination of three genes, including DMD, TYR, and LMNA, or RAG1, RAG2, and IL2RG, simultaneously, at the embryonic and cellular levels. CBEs also could disrupt genes (pol gene of porcine endogenous retrovirus) with dozens of copies by introducing multiple premature stop codons. With the CBEs, pigs carrying single gene or multiple gene point mutations were generated through embryo injection or nuclear transfer approach.
Artificial coiled coil biomineralisation protein for the synthesis of magnetic nanoparticles
Authors: Rawlings Andrea E. , Somner Lori A. , Fitzpatrick-Milton Michaela , Roebuck Thomas P. , Gwyn Christopher , Liravi Panah , Seville Victoria , Neal Thomas J. , Mykhaylyk Oleksandr O. , Baldwin Stephen A. , Staniland Sarah S.
Published: June 2019

Green synthesis of precise inorganic nanomaterials is a major challenge. Magnetotactic bacteria biomineralise magnetite nanoparticles (MNPs) within membrane vesicles (magnetosomes), which are embedded with dedicated proteins that control nanocrystal formation. Some such proteins are used in vitro to control MNP formation in green synthesis; however, these membrane proteins self-aggregate, making their production and use in vitro challenging and difficult to scale. Here, we provide an alternative solution by displaying active loops from biomineralisation proteins Mms13 and MmsF on stem-loop coiled-coil scaffold proteins (Mms13cc/MmsFcc). These artificial biomineralisation proteins form soluble, stable alpha-helical hairpin monomers, and MmsFcc successfully controls the formation of MNP when added to magnetite synthesis, regulating synthesis comparably to native MmsF. This study demonstrates how displaying active loops from membrane proteins on coiled-coil scaffolds removes membrane protein solubility issues, while retains activity, enabling a generic approach to readily-expressible, versatile, artificial membrane proteins for more accessible study and exploitation.