bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Table 2 from Biomarker Discovery in Non–Small Cell Lung Cancer: Integrating Gene Expression Profiling, Meta-analysis, and Tissue Microarray Validation
Authors: Botling Johan , Edlund Karolina , Lohr Miriam , Hellwig Birte , Holmberg Lars , Lambe Mats , Berglund Anders , Ekman Simon , Bergqvist Michael , Pontén Fredrik , König André , Fernandes Oswaldo , Karlsson Mats , Helenius Gisela , Karlsson Christina , Rahnenführer Jörg , Hengstler Jan G , Micke Patrick
Published: April 2023

PDF file - 25K, Characteristics of NSCLC patients from �rebro for tissue microarray analysis
Supplemental Material Section S3 from miRNA Landscape in Stage I Epithelial Ovarian Cancer Defines the Histotype Specificities
Authors: Calura Enrica , Fruscio Robert , Paracchini Lara , Bignotti Eliana , Ravaggi Antonella , Martini Paolo , Sales Gabriele , Beltrame Luca , Clivio Luca , Ceppi Lorenzo , Di Marino Mariacristina , Fuso Nerini Ilaria , Zanotti Laura , Cavalieri Duccio , Cattoretti Giorgio , Perego Patrizia , Milani Rodolfo , Katsaros Dionyssios , Tognon Germana , Sartori Enrico , Pecorelli Sergio , Mangioni Costantino , D'Incalci Maurizio , Romualdi Chiara , Marchini Sergio
Published: April 2023

PDF file - 162K, Human Ovarian Surface Epithelium (HOSE) experiments and analyses.
Supplementary Table 1 from Biomarker Discovery in Non–Small Cell Lung Cancer: Integrating Gene Expression Profiling, Meta-analysis, and Tissue Microarray Validation
Authors: Botling Johan , Edlund Karolina , Lohr Miriam , Hellwig Birte , Holmberg Lars , Lambe Mats , Berglund Anders , Ekman Simon , Bergqvist Michael , Pontén Fredrik , König André , Fernandes Oswaldo , Karlsson Mats , Helenius Gisela , Karlsson Christina , Rahnenführer Jörg , Hengstler Jan G , Micke Patrick
Published: April 2023

PDF file - 29K, Characteristics of NSCLC patients from Uppsala for tissue microarray analysis
Supplemental Material Section S2 from miRNA Landscape in Stage I Epithelial Ovarian Cancer Defines the Histotype Specificities
Authors: Calura Enrica , Fruscio Robert , Paracchini Lara , Bignotti Eliana , Ravaggi Antonella , Martini Paolo , Sales Gabriele , Beltrame Luca , Clivio Luca , Ceppi Lorenzo , Di Marino Mariacristina , Fuso Nerini Ilaria , Zanotti Laura , Cavalieri Duccio , Cattoretti Giorgio , Perego Patrizia , Milani Rodolfo , Katsaros Dionyssios , Tognon Germana , Sartori Enrico , Pecorelli Sergio , Mangioni Costantino , D'Incalci Maurizio , Romualdi Chiara , Marchini Sergio
Published: April 2023

PDF file - 126K, Survival analysis methodology and results for each histotype.
Supplementary Figures 1 - 3 from MAX Mutations Cause Hereditary and Sporadic Pheochromocytoma and Paraganglioma
Authors: Burnichon Nelly , Cascón Alberto , Schiavi Francesca , Morales Nicole Paes , Comino-Méndez Iñaki , Abermil Nasséra , Inglada-Pérez Lucía , de Cubas Aguirre A. , Amar Laurence , Barontini Marta , de Quirós Sandra Bernaldo , Bertherat Jérôme , Bignon Yves-Jean , Blok Marinus J. , Bobisse Sara , Borrego Salud , Castellano Maurizio , Chanson Philippe , Chiara María-Dolores , Corssmit Eleonora P.M. , Giacchè Mara , de Krijger Ronald R. , Ercolino Tonino , Girerd Xavier , Gómez-García Encarna B. , Gómez-Graña Álvaro , Guilhem Isabelle , Hes Frederik J. , Honrado Emiliano , Korpershoek Esther , Lenders Jacques W.M. , Letón Rocío , Mensenkamp Arjen R. , Merlo Anna , Mori Luigi , Murat Arnaud , Pierre Peggy , Plouin Pierre-François , Prodanov Tamara , Quesada-Charneco Miguel , Qin Nan , Rapizzi Elena , Raymond Victoria , Reisch Nicole , Roncador Giovanna , Ruiz-Ferrer Macarena , Schillo Frank , Stegmann Alexander P.A. , Suarez Carlos , Taschin Elisa , Timmers Henri J.L.M. , Tops Carli M.J. , Urioste Miguel , Beuschlein Felix , Pacak Karel , Mannelli Massimo , Dahia Patricia L. M. , Opocher Giuseppe , Eisenhofer Graeme , Gimenez-Roqueplo Anne-Paule , Robledo Mercedes
Published: April 2023

PDF file, 794KB, Supplementary figure S1. Gross MAX deletion analysis Supplementary figure S2. Immunohistochemical assessment. Supplementary figure S3. Pedigree of 3 families with affected relatives in more than one generation.
Supplementary Table 4 from Characterization of Gene Amplification–Driven SKP2 Overexpression in Myxofibrosarcoma: Potential Implications in Tumor Progression and Therapeutics
Authors: Li Chien-Feng , Wang Ju-Ming , Kang Hong-Yo , Huang Chiung-Kuei , Wang Jun-Wen , Fang Fu-Min , Wang Yu-Hui , Wu Wen-Ren , Li Shau-Hsuan , Yu Shih-Chen , Lee Jen-Chieh , Lan Jui , Shiue Yow-Ling , Wu Li-Ching , Huang Hsuan-Ying
Published: April 2023

PDF file - 70K
Supplementary Table 5 from Evaluation and Clinical Analyses of Downstream Targets of the Akt Inhibitor GDC-0068
Authors: Yan Yibing , Serra Violeta , Prudkin Ludmila , Scaltriti Maurizio , Murli Sumati , Rodríguez Olga , Guzman Marta , Sampath Deepak , Nannini Michelle , Xiao Yuanyuan , Wagle Marie-Claire , Wu Jenny Q. , Wongchenko Matthew , Hampton Garret , Ramakrishnan Vanitha , Lackner Mark R. , Saura Cristina , Roda Desamparados , Cervantes Andrés , Tabernero Josep , Patel Premal , Baselga José
Published: April 2023

XLS file 37K, RPPA quantification of laser captured microscopy needle biopsies in patients from the 100mg cohort
Supplementary Table 3 from Evaluation and Clinical Analyses of Downstream Targets of the Akt Inhibitor GDC-0068
Authors: Yan Yibing , Serra Violeta , Prudkin Ludmila , Scaltriti Maurizio , Murli Sumati , Rodríguez Olga , Guzman Marta , Sampath Deepak , Nannini Michelle , Xiao Yuanyuan , Wagle Marie-Claire , Wu Jenny Q. , Wongchenko Matthew , Hampton Garret , Ramakrishnan Vanitha , Lackner Mark R. , Saura Cristina , Roda Desamparados , Cervantes Andrés , Tabernero Josep , Patel Premal , Baselga José
Published: April 2023

PDF file 168K, Pearson and Spearman correlation with survival fraction for all cell lines together or individual cell lines
Supplementary Figure 5 from Characterization of Gene Amplification–Driven SKP2 Overexpression in Myxofibrosarcoma: Potential Implications in Tumor Progression and Therapeutics
Authors: Li Chien-Feng , Wang Ju-Ming , Kang Hong-Yo , Huang Chiung-Kuei , Wang Jun-Wen , Fang Fu-Min , Wang Yu-Hui , Wu Wen-Ren , Li Shau-Hsuan , Yu Shih-Chen , Lee Jen-Chieh , Lan Jui , Shiue Yow-Ling , Wu Li-Ching , Huang Hsuan-Ying
Published: April 2023

PDF file - 93K, The time- and dose-dependent increase in caspase-3/7 activity is confirmed by chemiluminescent assays after OH931 (upper) and NMFH-1 (lower) cells are treated with 5 nM, 10 nM, and 20 nM bortezomib for 48 and 72 hours.
Supplementary Figure 4 from Evaluation and Clinical Analyses of Downstream Targets of the Akt Inhibitor GDC-0068
Authors: Yan Yibing , Serra Violeta , Prudkin Ludmila , Scaltriti Maurizio , Murli Sumati , Rodríguez Olga , Guzman Marta , Sampath Deepak , Nannini Michelle , Xiao Yuanyuan , Wagle Marie-Claire , Wu Jenny Q. , Wongchenko Matthew , Hampton Garret , Ramakrishnan Vanitha , Lackner Mark R. , Saura Cristina , Roda Desamparados , Cervantes Andrés , Tabernero Josep , Patel Premal , Baselga José
Published: April 2023

PDF file 64K, Unsupervised clustering of the core biomarker modulation in cell lines, xenograft tumors, and in tumors from three patients in the 100mg cohort
Supplementary Figure 3 from Evaluation and Clinical Analyses of Downstream Targets of the Akt Inhibitor GDC-0068
Authors: Yan Yibing , Serra Violeta , Prudkin Ludmila , Scaltriti Maurizio , Murli Sumati , Rodríguez Olga , Guzman Marta , Sampath Deepak , Nannini Michelle , Xiao Yuanyuan , Wagle Marie-Claire , Wu Jenny Q. , Wongchenko Matthew , Hampton Garret , Ramakrishnan Vanitha , Lackner Mark R. , Saura Cristina , Roda Desamparados , Cervantes Andrés , Tabernero Josep , Patel Premal , Baselga José
Published: April 2023

PDF file 252K, In vivo pharmacodynamic IHC-based biomarker dose-response quantifications
Supplementary Figure 2 from Evaluation and Clinical Analyses of Downstream Targets of the Akt Inhibitor GDC-0068
Authors: Yan Yibing , Serra Violeta , Prudkin Ludmila , Scaltriti Maurizio , Murli Sumati , Rodríguez Olga , Guzman Marta , Sampath Deepak , Nannini Michelle , Xiao Yuanyuan , Wagle Marie-Claire , Wu Jenny Q. , Wongchenko Matthew , Hampton Garret , Ramakrishnan Vanitha , Lackner Mark R. , Saura Cristina , Roda Desamparados , Cervantes Andrés , Tabernero Josep , Patel Premal , Baselga José
Published: April 2023

PDF file 155K, Principal component analysis (PCA) of the ten biomarkers provides a biomarker profile for each cell line
Supplementary Table 1 from Endoglin (CD105) Contributes to Platinum Resistance and Is A Target for Tumor-Specific Therapy in Epithelial Ovarian Cancer
Authors: Ziebarth Angela J. , Nowsheen Somaira , Steg Adam D. , Shah Monjri M. , Katre Ashwini A. , Dobbin Zachary C. , Han Hee-Dong , Lopez-Berestein Gabriel , Sood Anil K. , Conner Michael , Yang Eddy S. , Landen Charles N.
Published: April 2023

PDF file - 72K, QPCR array for DNA Damage genes after endoglin downregulation
Supplementary Methods, Figure Legends 1-3 from In Vivo Positron Emission Tomography Imaging of Protease Activity by Generation of a Hydrophobic Product from a Noninhibitory Protease Substrate
Authors: Chuang Chih-Hung , Chuang Kuo-Hsiang , Wang Hsin-Ell , Roffler Steve R. , Shiea Jen-taie , Tzou Shey-Cherng , Cheng Ta-Chun , Kao Chien-Han , Wu Shih-Yen , Tseng Wei-Lung , Cheng Chiu-Min , Hou Ming-Feng , Wang Ju-Ming , Cheng Tian-Lu
Published: April 2023

PDF file - 92K, Supplementary Material & Methods and Figure legends.
Supplementary Table 1 from Phase I Trial of a Glypican-3–Derived Peptide Vaccine for Advanced Hepatocellular Carcinoma: Immunologic Evidence and Potential for Improving Overall Survival
Authors: Sawada Yu , Yoshikawa Toshiaki , Nobuoka Daisuke , Shirakawa Hirofumi , Kuronuma Toshimitsu , Motomura Yutaka , Mizuno Shoichi , Ishii Hiroshi , Nakachi Kohei , Konishi Masaru , Nakagohri Toshio , Takahashi Shinichiro , Gotohda Naoto , Takayama Tadatoshi , Yamao Kenji , Uesaka Katsuhiko , Furuse Junji , Kinoshita Taira , Nakatsura Tetsuya
Published: April 2023

PDF file, 28KB, The levels of AFP or DCP decreased temporarily at least once in nine of the 33 patients. In seven of these nine patients, the levels of DCP fell to < 30% of baseline values.
Related Article from PET Imaging of Tumor Growth: Not as Easy as It Looks
Authors: Shields Anthony F.
Published: April 2023

Related Article from PET Imaging of Tumor Growth: Not as Easy as It Looks
Figure S1 from A Novel Engineered Anti-CD20 Tracer Enables Early Time PET Imaging in a Humanized Transgenic Mouse Model of B-cell Non-Hodgkins Lymphoma
Authors: Natarajan Arutselvan , Hackel Benjamin J. , Gambhir Sanjiv Sam
Published: April 2023

PDF file 524K, MicroPET images are Ramos CD20 (+) tumor bearing mice (n= 3) administered with 64Cu-Do-FN3CD20 (A) and 64Cu-Do-rituximab (B) tracers. Coronal images of PET were acquired after 4h and 24h (PET/CT) p.i. Organs uptake presented in the table were mean plus-minus SD {plus-minus} ID/g measured by either ROI or by ex vivo weighing (Bio) sacrificed after 24h p.i and counting the tissues in gamma counter. L= Liver, K= Kidney, BP = blood pool, and arrow = tumor. ND: not detected. T: O = tumor to organ ratio liver, kidney and spleen
Supplementary Table 1 from Establishment and Characterization of Novel Cell Lines from Sinonasal Undifferentiated Carcinoma
Authors: Takahashi Yoko , Kupferman Michael E. , Bell Diana , Jiffar Tilahun , Lee June Goo , Xie Tong-Xin , Li Ning-Wei , Zhao Mei , Frederick Mitchell J. , Gelbard Alexander , Myers Jeffrey N. , Hanna Ehab Y.
Published: April 2023

PDF file - 88K, STR profile of the original specimen and MDA8788 cells
Supplementary Figures 1-3 from Frequent Inactivation of Cysteine Dioxygenase Type 1 Contributes to Survival of Breast Cancer Cells and Resistance to Anthracyclines
Authors: Jeschke Jana , O'Hagan Heather M. , Zhang Wei , Vatapalli Rajita , Calmon Marilia Freitas , Danilova Ludmila , Nelkenbrecher Claudia , Van Neste Leander , Bijsmans Ingrid T.G.W. , Van Engeland Manon , Gabrielson Edward , Schuebel Kornel E. , Winterpacht Andreas , Baylin Stephen B. , Herman James G. , Ahuja Nita
Published: April 2023

PDF File - 383K, Supplementary Figure 1 displays genomic location, structure and CpG island of the CDO1 gene.
Supplementary Figure Legend and Table 1 from Scatter Spectroscopic Imaging Distinguishes between Breast Pathologies in Tissues Relevant to Surgical Margin Assessment
Authors: Laughney Ashley M. , Krishnaswamy Venkataramanan , Rizzo Elizabeth J. , Schwab Mary C. , Barth Richard J. , Pogue Brian W. , Paulsen Keith D. , Wells Wendy A.
Published: April 2023

PDF file, 133K, Diagnostic distribution of tissue population and mean+/-standard deviation for spectrally derived scattering parameters per diagnostic category.
Supplementary Figure 2 from Establishment and Characterization of Novel Cell Lines from Sinonasal Undifferentiated Carcinoma
Authors: Takahashi Yoko , Kupferman Michael E. , Bell Diana , Jiffar Tilahun , Lee June Goo , Xie Tong-Xin , Li Ning-Wei , Zhao Mei , Frederick Mitchell J. , Gelbard Alexander , Myers Jeffrey N. , Hanna Ehab Y.
Published: April 2023

PDF file - 133K, In vitro migration and invasion assays in MDA8788-6 cells. 4 x 104 cells were plated in insert wells or Matrigel-coated wells in the presence of 10% FBS. After 48 hours, OSC19 used as a positive control showed massive migration and invasion, whereas MDA8788-6 did not show any of them. The original magnification is x50.
CCR Translation for This Article from Scatter Spectroscopic Imaging Distinguishes between Breast Pathologies in Tissues Relevant to Surgical Margin Assessment
Authors: Laughney Ashley M. , Krishnaswamy Venkataramanan , Rizzo Elizabeth J. , Schwab Mary C. , Barth Richard J. , Pogue Brian W. , Paulsen Keith D. , Wells Wendy A.
Published: April 2023

CCR Translation for This Article from Scatter Spectroscopic Imaging Distinguishes between Breast Pathologies in Tissues Relevant to Surgical Margin Assessment
Supplementary Figures 1 - 2 from MicroRNA-148a Suppresses Tumor Cell Invasion and Metastasis by Downregulating ROCK1 in Gastric Cancer
Authors: Zheng Biqiang , Liang Linhui , Wang Chunmeng , Huang Shenglin , Cao Xi , Zha Ruopeng , Liu Li , Jia Deshui , Tian Qi , Wu Jianghong , Ye Yanwei , Wang Qifeng , Long Ziwen , Zhou Ye , Du Chunyan , He Xianghuo , Shi Yingqiang
Published: April 2023

PDF file - 223KB
Supplementary Tables 1 - 7 from Biomarker Analyses from a Placebo-Controlled Phase II Study Evaluating Erlotinib ± Onartuzumab in Advanced Non–Small Cell Lung Cancer: MET Expression Levels Are Predictive of Patient Benefit
Authors: Koeppen Hartmut , Yu Wei , Zha Jiping , Pandita Ajay , Penuel Elicia , Rangell Linda , Raja Rajiv , Mohan Sankar , Patel Rajesh , Desai Rupal , Fu Ling , Do An , Parab Vaishali , Xia Xiaoling , Januario Tom , Louie Sharianne G. , Filvaroff Ellen , Shames David S. , Wistuba Ignacio , Lipkind Marina , Huang Jenny , Lazarov Mirella , Ramakrishnan Vanitha , Amler Lukas , Phan See-Chun , Patel Premal , Peterson Amy , Yauch Robert L.
Published: April 2023

Table S1. Overlap of biomarkers measured in OAM4558g; Table S2. Primer/probe information; Table S3. MET diagnostic scoring criteria; Table S4. MET IHC intratumoral heterogeneity; Table S5. Impact of KRAS/EGFR mutation on clinical outcome; Table S6. Biomarker status in EGFR-mutant patients; Table S7. Association of transcript expression with PFS in OAM4558g.
Supplementary Figure Legend from The Pivotal Role of Integrin β1 in Metastasis of Head and Neck Squamous Cell Carcinoma
Authors: Wang Dongsheng , Müller Susan , Amin A.R.M. Ruhul , Huang Donghai , Su Ling , Hu Zhongliang , Rahman Mohammad Aminur , Nannapaneni Sreenivas , Koenig Lydia , Chen Zhengjia , Tighiouart Mourad , Shin Dong M. , Chen Zhuo G.
Published: April 2023

PDF file, 65K.
Supplementary Methods from Biomarker Analyses from a Placebo-Controlled Phase II Study Evaluating Erlotinib ± Onartuzumab in Advanced Non–Small Cell Lung Cancer: MET Expression Levels Are Predictive of Patient Benefit
Authors: Koeppen Hartmut , Yu Wei , Zha Jiping , Pandita Ajay , Penuel Elicia , Rangell Linda , Raja Rajiv , Mohan Sankar , Patel Rajesh , Desai Rupal , Fu Ling , Do An , Parab Vaishali , Xia Xiaoling , Januario Tom , Louie Sharianne G. , Filvaroff Ellen , Shames David S. , Wistuba Ignacio , Lipkind Marina , Huang Jenny , Lazarov Mirella , Ramakrishnan Vanitha , Amler Lukas , Phan See-Chun , Patel Premal , Peterson Amy , Yauch Robert L.
Published: April 2023

Additional methodology describing cell lines and tissues, as well as detailed methodology for gene expression, flow cytometry, IHC and FISH studies.
Supplementary Figure 5 from The Pivotal Role of Integrin β1 in Metastasis of Head and Neck Squamous Cell Carcinoma
Authors: Wang Dongsheng , Müller Susan , Amin A.R.M. Ruhul , Huang Donghai , Su Ling , Hu Zhongliang , Rahman Mohammad Aminur , Nannapaneni Sreenivas , Koenig Lydia , Chen Zhengjia , Tighiouart Mourad , Shin Dong M. , Chen Zhuo G.
Published: April 2023

PDF file, 104K, Knock-down of integrin β1 expression significantly reduced p-ERK levels in M4E and PCI-37B cells.
Supplementary Table 3 from Novel Role of MDA-9/Syntenin in Regulating Urothelial Cell Proliferation by Modulating EGFR Signaling
Authors: Dasgupta Santanu , Menezes Mitchell E. , Das Swadesh K. , Emdad Luni , Janjic Aleksandar , Bhatia Shilpa , Mukhopadhyay Nitai D. , Shao Chunbo , Sarkar Devanand , Fisher Paul B.
Published: April 2023

PDF file - 64K, Table S3. Expression level of EGFR, c-Src (Y418), CTNNB1 (Y333), AKT (S473) and E-cadherin in the primary UCC tumors
Supplementary Figure 6 from Novel Role of MDA-9/Syntenin in Regulating Urothelial Cell Proliferation by Modulating EGFR Signaling
Authors: Dasgupta Santanu , Menezes Mitchell E. , Das Swadesh K. , Emdad Luni , Janjic Aleksandar , Bhatia Shilpa , Mukhopadhyay Nitai D. , Shao Chunbo , Sarkar Devanand , Fisher Paul B.
Published: April 2023

PDF file - 1070K, Supplementary Figure S6: A steady-state level of MDA-9/Syntenin expression was evident in the in vivo lung metastasis of T24 cells transfected with an empty vector. Magnification X 200
Supplementary Figure 5 from Novel Role of MDA-9/Syntenin in Regulating Urothelial Cell Proliferation by Modulating EGFR Signaling
Authors: Dasgupta Santanu , Menezes Mitchell E. , Das Swadesh K. , Emdad Luni , Janjic Aleksandar , Bhatia Shilpa , Mukhopadhyay Nitai D. , Shao Chunbo , Sarkar Devanand , Fisher Paul B.
Published: April 2023

PDF file - 6610K, Supplementary Figure S5: Co-expression signature of MDA-9/Syntenin, EGFR, AKT, �-catenin, E-cadherin and c-Src in primary UCC tumors
Supplementary Figure 3 from Chromosome 5q Loss in Colorectal Flat Adenomas
Authors: Voorham Quirinus J.M. , Carvalho Beatriz , Spiertz Angela J. , van Grieken Nicole C.T. , Mongera Sandra , Rondagh Eveline J.A. , van de Wiel Mark A. , Jordanova Ekaterina S. , Ylstra Bauke , Kliment Martin , Grabsch Heike , Rembacken Bjorn J. , Arai Tomio , de Bruïne Adriaan P. , Sanduleanu Silvia , Quirke Philip , Mulder Chris J.J. , van Engeland Manon , Meijer Gerrit A.
Published: April 2023

PDF file, 4178K, Frequency plot of different subtypes, dysplasia, origin, gender, age and location.
Supplementary Figure 2 from Chromosome 5q Loss in Colorectal Flat Adenomas
Authors: Voorham Quirinus J.M. , Carvalho Beatriz , Spiertz Angela J. , van Grieken Nicole C.T. , Mongera Sandra , Rondagh Eveline J.A. , van de Wiel Mark A. , Jordanova Ekaterina S. , Ylstra Bauke , Kliment Martin , Grabsch Heike , Rembacken Bjorn J. , Arai Tomio , de Bruïne Adriaan P. , Sanduleanu Silvia , Quirke Philip , Mulder Chris J.J. , van Engeland Manon , Meijer Gerrit A.
Published: April 2023

PDF file, 1948K, Frequency plot of different histology types.
Supplementary Figure 3 from Novel Role of MDA-9/Syntenin in Regulating Urothelial Cell Proliferation by Modulating EGFR Signaling
Authors: Dasgupta Santanu , Menezes Mitchell E. , Das Swadesh K. , Emdad Luni , Janjic Aleksandar , Bhatia Shilpa , Mukhopadhyay Nitai D. , Shao Chunbo , Sarkar Devanand , Fisher Paul B.
Published: April 2023

PDF file - 1469K, Supplementary Figure S3: Membranous (yellow arrow) and cytoplasmic (white arrow) co-localization of MDA-9/Syntenin and EGFR in T24 cells
Supplementary Figure 2 from Novel Role of MDA-9/Syntenin in Regulating Urothelial Cell Proliferation by Modulating EGFR Signaling
Authors: Dasgupta Santanu , Menezes Mitchell E. , Das Swadesh K. , Emdad Luni , Janjic Aleksandar , Bhatia Shilpa , Mukhopadhyay Nitai D. , Shao Chunbo , Sarkar Devanand , Fisher Paul B.
Published: April 2023

PDF file - 621K, Supplementary Figure S2: Immunofluorescence analysis of EGFR and C-Src (Y418) expression in MDA-9/syntenin-depleted T24 cells
Supplementary Methods, Table 1, Figure Legends 1-2 from A Phase I Study of Veliparib in Combination with Metronomic Cyclophosphamide in Adults with Refractory Solid Tumors and Lymphomas
Authors: Kummar Shivaani , Ji Jiuping , Morgan Robert , Lenz Heinz-Josef , Puhalla Shannon L. , Belani Chandra P. , Gandara David R. , Allen Deborah , Kiesel Brian , Beumer Jan H. , Newman Edward M. , Rubinstein Larry , Chen Alice , Zhang Yiping , Wang Lihua , Kinders Robert J. , Parchment Ralph E. , Tomaszewski Joseph E. , Doroshow James H.
Published: April 2023

PDF file - 86K
Supplementary Figure S2 from Prospective Phase II Study on 5-Days Azacitidine for Treatment of Symptomatic and/or Erythropoietin Unresponsive Patients with Low/INT-1–Risk Myelodysplastic Syndromes
Authors: Filì Carla , Malagola Michele , Follo Matilde Y. , Finelli Carlo , Iacobucci Ilaria , Martinelli Giovanni , Cattina Federica , Clissa Cristina , Candoni Anna , Fanin Renato , Gobbi Marco , Bocchia Monica , Defina Marzia , Spedini Pierangelo , Skert Cristina , Manzoli Lucia , Cocco Lucio , Russo Domenico
Published: April 2023

Supplementary Figure S2 - PDF file 145K, Representation from Chromosome Analysis Suite (Chas, Affymetrix) of LOH alterations in analyzed MDS patients.The figure represents the LOH of the 5 patients with this abnormality and shows its distribution and its size within the chromosomes
Supplementary Figure 2 from Development of [11C]erlotinib Positron Emission Tomography for In Vivo Evaluation of EGF Receptor Mutational Status
Authors: Bahce Idris , Smit Egbert F. , Lubberink Mark , van der Veldt Astrid A. M. , Yaqub Maqsood , Windhorst Albert D. , Schuit Robert C. , Thunnissen Erik , Heideman Daniëlle A. M. , Postmus Pieter E. , Lammertsma Adriaan A. , Hendrikse N. Harry
Published: April 2023

PDF file - 46K, Metabolite analysis. Mean fractions of parent 11Cerlotinib, nonpolar metabolites and polar metabolites for groups 1 (filled symbols) and 2 (open symbols). Vertical bars indicate standard deviations.
Supplementary Figure 1 from Development of [11C]erlotinib Positron Emission Tomography for In Vivo Evaluation of EGF Receptor Mutational Status
Authors: Bahce Idris , Smit Egbert F. , Lubberink Mark , van der Veldt Astrid A. M. , Yaqub Maqsood , Windhorst Albert D. , Schuit Robert C. , Thunnissen Erik , Heideman Daniëlle A. M. , Postmus Pieter E. , Lammertsma Adriaan A. , Hendrikse N. Harry
Published: April 2023

PDF file - 43K, Synthesis of 11Cerlotinib. Reaction conditions: 1.0 mg (2.6 μmole) of (1) 6-O-desmethyl-erlotinib, 11CCH3I, 250 μL of acetonitrile, 4.6 μmole of tetra-n-butylammonium hydroxide (2.0 μL of a 60% solution in water), 80 {degree sign}C, 5 min.
Supplementary Figure 3 from Adverse Outcomes in Clear Cell Renal Cell Carcinoma with Mutations of 3p21 Epigenetic Regulators BAP1 and SETD2: A Report by MSKCC and the KIRC TCGA Research Network
Authors: Hakimi A. Ari , Ostrovnaya Irina , Reva Boris , Schultz Nikolaus , Chen Ying-Bei , Gonen Mithat , Liu Han , Takeda Shugaku , Voss Martin H. , Tickoo Satish K. , Reuter Victor E. , Russo Paul , Cheng Emily H. , Sander Chris , Motzer Robert J. , Hsieh James J.
Published: April 2023

PDF File - 106K, MSKCC mutation combination cancer specific survival curves.
Supplementary Figure 2 from Adverse Outcomes in Clear Cell Renal Cell Carcinoma with Mutations of 3p21 Epigenetic Regulators BAP1 and SETD2: A Report by MSKCC and the KIRC TCGA Research Network
Authors: Hakimi A. Ari , Ostrovnaya Irina , Reva Boris , Schultz Nikolaus , Chen Ying-Bei , Gonen Mithat , Liu Han , Takeda Shugaku , Voss Martin H. , Tickoo Satish K. , Reuter Victor E. , Russo Paul , Cheng Emily H. , Sander Chris , Motzer Robert J. , Hsieh James J.
Published: April 2023

PDF File - 357K, (A) Time to recurrence with SETD2 mutations in TCGA cohort (p= 0.002). (B) Time to recurrence curves for all other mutations in the TCGA cohort, all other mutations non-significant for TTR.
Supplementary Tables S18-20 from Functional Kinomics Identifies Candidate Therapeutic Targets in Head and Neck Cancer
Authors: Moser Russell , Xu Chang , Kao Michael , Annis James , Lerma Luisa Angelica , Schaupp Christopher M. , Gurley Kay E. , Jang In Sock , Biktasova Asel , Yarbrough Wendell G. , Margolin Adam A. , Grandori Carla , Kemp Christopher J. , Méndez Eduardo
Published: April 2023

Tables S18-20: Table S18. Secondary validation assay statistical analysis (absolute viability) Table S19. Differential viability and caspase 3/7 dependent apoptosis AUC of secondary validation assay Table S20. Statistical analysis summary differential viability and caspase 3/7 dependent apoptosis
Supplementary Figure 3 from Combination Small Molecule MEK and PI3K Inhibition Enhances Uveal Melanoma Cell Death in a Mutant GNAQ- and GNA11-Dependent Manner
Authors: Khalili Jahan S. , Yu Xiaoxing , Wang Ji , Hayes Brendan C. , Davies Michael A. , Lizee Gregory , Esmaeli Bita , Woodman Scott E.
Published: April 2023

PDF file, 177K, Uveal melanoma cells were treated with increasing doses of MEKi or PI3Ki and impedance measurements ascertained at 10 min intervals.
Supplementary Figure 2 from Combination Small Molecule MEK and PI3K Inhibition Enhances Uveal Melanoma Cell Death in a Mutant GNAQ- and GNA11-Dependent Manner
Authors: Khalili Jahan S. , Yu Xiaoxing , Wang Ji , Hayes Brendan C. , Davies Michael A. , Lizee Gregory , Esmaeli Bita , Woodman Scott E.
Published: April 2023

PDF file, 106K, Uveal melanoma cells (UPMD1 and OMM1) were treated with increasing concentrations of MEKi (0 - 1000 nM) or PI3Ki (0 - 1000 nM) x 4hours. Western blot analysis of phosphorylated MAPK1/2, total MAPK2, phosphorylated AKT, and total AKT following treatment are presented.
Supplementary Figure 1 from Combination Small Molecule MEK and PI3K Inhibition Enhances Uveal Melanoma Cell Death in a Mutant GNAQ- and GNA11-Dependent Manner
Authors: Khalili Jahan S. , Yu Xiaoxing , Wang Ji , Hayes Brendan C. , Davies Michael A. , Lizee Gregory , Esmaeli Bita , Woodman Scott E.
Published: April 2023

PDF file, 55K, Baseline protein expression of phosphorylated MAPK1/2, total MAPK1/2, phosphorylated AKT, total AKT in uveal melanoma cell lines.
Supplementary Figure S2 from Functional Kinomics Identifies Candidate Therapeutic Targets in Head and Neck Cancer
Authors: Moser Russell , Xu Chang , Kao Michael , Annis James , Lerma Luisa Angelica , Schaupp Christopher M. , Gurley Kay E. , Jang In Sock , Biktasova Asel , Yarbrough Wendell G. , Margolin Adam A. , Grandori Carla , Kemp Christopher J. , Méndez Eduardo
Published: April 2023

Figure S2. HFF kinase exclusion plot
Supplementary Figure 1 from Antibody-Dependent Cell-Mediated Cytotoxicity Overcomes NK Cell Resistance in MLL-Rearranged Leukemia Expressing Inhibitory KIR Ligands but Not Activating Ligands
Authors: Chan Wing Keung , Kung Sutherland May , Li Ying , Zalevsky Jonathan , Schell Sarah , Leung Wing
Published: April 2023

PDF file - 61K, Minimum effective effector:target (E:T) ratio for lintuzumab on CD33+ MV4-11 cells with or without KIR blockcade. NK cells were co-cultured with MV4-11 cells pretreated with 0, 10, 100 and 1000 ng/mL lintuzumab with or without 10 μg/mL KIR blockcade pan MHCI antibody at E:T ratio of 1:1, 5:1, 10:1 and 20:1. The specific lysis of MV4-11 cells were plotted and the results were from triplicate wells and repeats using NK cells from two different donors
Supplementary Table S1 from A Dendritic Cell Vaccine Pulsed with Autologous Hypochlorous Acid-Oxidized Ovarian Cancer Lysate Primes Effective Broad Antitumor Immunity: From Bench to Bedside
Authors: Chiang Cheryl Lai-Lai , Kandalaft Lana E. , Tanyi Janos , Hagemann Andrea R. , Motz Gregory T. , Svoronos Nikolaos , Montone Kathleen , Mantia-Smaldone Gina M. , Smith Lori , Nisenbaum Harvey L. , Levine Bruce L. , Kalos Michael , Czerniecki Brian J. , Torigian Drew A. , Powell Daniel J. , Mick Rosemarie , Coukos George
Published: April 2023

Supplementary Table S1 - PDF file 191K, Cytokine and chemokine productions from DCs of ovarian cancer subjects that were loaded with HOCl-oxidized autologous whole tumor lysate and matured with LPS and IFN-gamma
Supplementary Figure S3 from A Dendritic Cell Vaccine Pulsed with Autologous Hypochlorous Acid-Oxidized Ovarian Cancer Lysate Primes Effective Broad Antitumor Immunity: From Bench to Bedside
Authors: Chiang Cheryl Lai-Lai , Kandalaft Lana E. , Tanyi Janos , Hagemann Andrea R. , Motz Gregory T. , Svoronos Nikolaos , Montone Kathleen , Mantia-Smaldone Gina M. , Smith Lori , Nisenbaum Harvey L. , Levine Bruce L. , Kalos Michael , Czerniecki Brian J. , Torigian Drew A. , Powell Daniel J. , Mick Rosemarie , Coukos George
Published: April 2023

Supplementary Figure S3 - PDF file 128K, OCDC manufacturing process. Elutriated monocytes were obtained from subjects after leukapheresis and cultured in cell factories as described in Materials and Methods. HOCl-oxidized autologous tumor lysate was pulsed onto DCs for 16 to 20 hours, followed by activation and maturation with LPS and IFN-gamma for 6 to 8 hours. On day 5 of culture, matured lysate-pulsed DCs were harvested and cryopreserved until required
Supplementary Figure S1 from A Dendritic Cell Vaccine Pulsed with Autologous Hypochlorous Acid-Oxidized Ovarian Cancer Lysate Primes Effective Broad Antitumor Immunity: From Bench to Bedside
Authors: Chiang Cheryl Lai-Lai , Kandalaft Lana E. , Tanyi Janos , Hagemann Andrea R. , Motz Gregory T. , Svoronos Nikolaos , Montone Kathleen , Mantia-Smaldone Gina M. , Smith Lori , Nisenbaum Harvey L. , Levine Bruce L. , Kalos Michael , Czerniecki Brian J. , Torigian Drew A. , Powell Daniel J. , Mick Rosemarie , Coukos George
Published: April 2023

Supplementary Figure S1 - PDF file 81K, DCs pulsed with HOCl-L efficiently tumor-specific CD4+ and SIINFEKL-specific CD8+ T-cell responses in mice. A, representative dotplots showing the % of SIINFEKL-pentamer specific CD8+ T-cells (gated) in the spleens of mice following DC-lysate vaccinations. B, the % of CD3+CD4+ IFN-gamma secreting T-cells in response to live ID8-ova tumor cells was quantified in spleens 2 weeks after the 3rd vaccine. Data was the mean of 3 independent experiments with 5 mice in each experiment
Data Supplement from Novel MSH6 Mutations in Treatment-Naïve Glioblastoma and Anaplastic Oligodendroglioma Contribute to Temozolomide Resistance Independently of MGMT Promoter Methylation
Authors: Nguyen Stephanie A. , Stechishin Owen D.M. , Luchman H. Artee , Lun Xueqing Q. , Senger Donna L. , Robbins Stephen M. , Cairncross J. Gregory , Weiss Samuel
Published: April 2023

Supplementary Figure Legend
Supplementary Figure 1 from BRAF Fusions Define a Distinct Molecular Subset of Melanomas with Potential Sensitivity to MEK Inhibition
Authors: Hutchinson Katherine E. , Lipson Doron , Stephens Philip J. , Otto Geoff , Lehmann Brian D. , Lyle Pamela L. , Vnencak-Jones Cindy L. , Ross Jeffrey S. , Pietenpol Jennifer A. , Sosman Jeffrey A. , Puzanov Igor , Miller Vincent A. , Pao William
Published: April 2023

PDF file - 57K, Supplementary Figure S1. Signaling properties of WT PAPSS1.
Data Supplement from Novel MSH6 Mutations in Treatment-Naïve Glioblastoma and Anaplastic Oligodendroglioma Contribute to Temozolomide Resistance Independently of MGMT Promoter Methylation
Authors: Nguyen Stephanie A. , Stechishin Owen D.M. , Luchman H. Artee , Lun Xueqing Q. , Senger Donna L. , Robbins Stephen M. , Cairncross J. Gregory , Weiss Samuel
Published: April 2023

Supplementary Figure 1. Detection of MSH6 somatic mutations by cDNA and genomic DNA sequencing. A-D, cDNA sequencing (A) revealed a heterozygous T1219I mutation that was also confirmed by sequencing the genomic DNA of cell line 119 (B) and the fresh frozen tumor from patient 119 (C). The T1219I mutation was not present in genomic DNA from a blood sample of patient 119 (D) demonstrating it to be of somatic rather than germline origin.
Supplementary Table 1 from Expression of Interleukin-4 Receptor Alpha in Human Pleural Mesothelioma Is Associated with Poor Survival and Promotion of Tumor Inflammation
Authors: Burt Bryan M. , Bader Andrew , Winter Daniel , Rodig Scott J. , Bueno Raphael , Sugarbaker David J.
Published: April 2023

PDF file - 40K
Supplementary Data from Stearoyl Co-A Desaturase 1 as a ccRCC Therapeutic Target: Death by Stress
Authors: Leung Janet Y. , Kim William Y.
Published: April 2023

Supplementary Data from Stearoyl Co-A Desaturase 1 as a ccRCC Therapeutic Target: Death by Stress
Supplementary Figure 1 from Expression of Interleukin-4 Receptor Alpha in Human Pleural Mesothelioma Is Associated with Poor Survival and Promotion of Tumor Inflammation
Authors: Burt Bryan M. , Bader Andrew , Winter Daniel , Rodig Scott J. , Bueno Raphael , Sugarbaker David J.
Published: April 2023

PDF file - 1.0MB
Supplementary Table 1 from MSH3 Protein Expression and Nodal Status in MLH1-Deficient Colorectal Cancers
Authors: Laghi Luigi , Bianchi Paolo , Delconte Gabriele , Celesti Giuseppe , Di Caro Giuseppe , Pedroni Monica , Chiaravalli Anna Maria , Jung Barbara , Capella Carlo , de Leon Maurizio Ponz , Malesci Alberto
Published: April 2023

PDF file, 95KB, Supplemental material 2. Tumor Features Associated with Nodal Involvement (N1or N2) at Pathological Staging of 109 Resected MSI CRC.
Supplementary Table 1 from The Zinc Finger Gene ZIC2 Has Features of an Oncogene and Its Overexpression Correlates Strongly with the Clinical Course of Epithelial Ovarian Cancer
Authors: Marchini Sergio , Poynor Elizabeth , Barakat Richard R. , Clivio Luca , Cinquini Michela , Fruscio Robert , Porcu Luca , Bussani Cecilia , D’Incalci Maurizio , Erba Eugenio , Romano Michela , Cattoretti Giorgio , Katsaros Dionyssios , Koff Andrew , Luzzatto Lucio
Published: April 2023

PDF file, 87K, Main characteristics of patients and tissues. A, clinical and histopathological parameters of the 232 EOT biopsies enrolled in the study and subdivided into tumor tissue collection A and B. UK unknown. n, number of patients enrolled. NA, not available.
Supplementary Methods, Figures 1 - 4, Tables 1 - 3 from Influence of Polymorphic OATP1B-Type Carriers on the Disposition of Docetaxel
Authors: de Graan Anne-Joy M. , Lancaster Cynthia S. , Obaidat Amanda , Hagenbuch Bruno , Elens Laure , Friberg Lena E. , de Bruijn Peter , Hu Shuiying , Gibson Alice A. , Bruun Gitte H. , Corydon Thomas J. , Mikkelsen Torben S. , Walker Aisha L. , Du Guoqing , Loos Walter J. , van Schaik Ron H. N. , Baker Sharyn D. , Mathijssen Ron H. J. , Sparreboom Alex
Published: April 2023

PDF file, 437KB, Description of determination of docetaxel concentrations; influence of phenol red on OATP1B1-mediated transport of docetaxel; characterization of paclitaxel concentration-dependent transport by OATP1B1 and OATP1B3; docetaxel clearance as a function of observed OATP1B1 (SLCO1B1) or OATP1B3 (SLCO1B3) diplotypes and genotypes; description of genotyped variants in OATP1B1 (SLCO1B1) and OATP1B3 (SLCO1B3); summary of patient demographics; and examples of OATP1B1 and OATP1B3 inhibitors.
Related Article from Second-Line Therapies in Hepatocellular Carcinoma: Emergence of Resistance to Sorafenib
Authors: Villanueva Augusto , Llovet Josep M.
Published: April 2023

Related Article from Second-Line Therapies in Hepatocellular Carcinoma: Emergence of Resistance to Sorafenib
Supplementary Tables 1 - 6 from FoxM1 Inhibition Sensitizes Resistant Glioblastoma Cells to Temozolomide by Downregulating the Expression of DNA-Repair Gene Rad51
Authors: Zhang Nu , Wu Xinjian , Yang Lixuan , Xiao Feizhe , Zhang Heng , Zhou Aidong , Huang Zhengsong , Huang Suyun
Published: April 2023

PDF file - 74K, S1 Characteristics of GBM1 and GBM2 tumors; S2 Primers used for real-time RT-PCR and ChIP assays; S3 Patient and treatment characteristics; S4 Immunohistochemical data summary of 38 pairs of samples; S5 Molecular features of the primary GBM samples; S6 Molecular features of recurrent GBM samples
Supplementary Figure 5 from FoxM1 Inhibition Sensitizes Resistant Glioblastoma Cells to Temozolomide by Downregulating the Expression of DNA-Repair Gene Rad51
Authors: Zhang Nu , Wu Xinjian , Yang Lixuan , Xiao Feizhe , Zhang Heng , Zhou Aidong , Huang Zhengsong , Huang Suyun
Published: April 2023

PDF file - 218K, Supplementary Fig.5. Rad51 re-expression partially rescued the tumor inhibition mediated by FoxM1 knockdown and Rad51 knockdown increased the TMZ sensitivity of recurrent GBM cells in vivo
Supplementary Table 2 from Transcriptional Characterization of a Prospective Series of Primary Plasma Cell Leukemia Revealed Signatures Associated with Tumor Progression and Poorer Outcome
Authors: Todoerti Katia , Agnelli Luca , Fabris Sonia , Lionetti Marta , Tuana Giacomo , Mosca Laura , Lombardi Luigia , Grieco Vitina , Bianchino Gabriella , D'Auria Fiorella , Statuto Teodora , Mazzoccoli Carmela , De Luca Luciana , Petrucci Maria Teresa , Morabito Fortunato , Offidani Massimo , Di Raimondo Francesco , Falcone Antonietta , Omede' Paola , Tassone Pierfrancesco , Boccadoro Mario , Palumbo Antonio , Neri Antonino , Musto Pellegrino
Published: April 2023

PDF file - 156K, 503-gene list differentially expressed between pPCL and MM.
Data Supplement from Functional p38 MAPK Identified by Biomarker Profiling of Pancreatic Cancer Restrains Growth through JNK Inhibition and Correlates with Improved Survival
Authors: Zhong Yi , Naito Yoshiki , Cope Leslie , Naranjo-Suarez Salvador , Saunders Tyler , Hong Seung-Mo , Goggins Michael G. , Herman Joseph M. , Wolfgang Christopher L. , Iacobuzio-Donahue Christine A.
Published: April 2023

Supplemental Figure 1. Box Plots.
Supplementary Figure 3 from Transcriptional Characterization of a Prospective Series of Primary Plasma Cell Leukemia Revealed Signatures Associated with Tumor Progression and Poorer Outcome
Authors: Todoerti Katia , Agnelli Luca , Fabris Sonia , Lionetti Marta , Tuana Giacomo , Mosca Laura , Lombardi Luigia , Grieco Vitina , Bianchino Gabriella , D'Auria Fiorella , Statuto Teodora , Mazzoccoli Carmela , De Luca Luciana , Petrucci Maria Teresa , Morabito Fortunato , Offidani Massimo , Di Raimondo Francesco , Falcone Antonietta , Omede' Paola , Tassone Pierfrancesco , Boccadoro Mario , Palumbo Antonio , Neri Antonino , Musto Pellegrino
Published: April 2023

PDF file - 114K, Boxplots of differentially expressed genes between pPCL and MM patients as determined by Q-RT-PCR.
Supplementary Figure 2 from Transcriptional Characterization of a Prospective Series of Primary Plasma Cell Leukemia Revealed Signatures Associated with Tumor Progression and Poorer Outcome
Authors: Todoerti Katia , Agnelli Luca , Fabris Sonia , Lionetti Marta , Tuana Giacomo , Mosca Laura , Lombardi Luigia , Grieco Vitina , Bianchino Gabriella , D'Auria Fiorella , Statuto Teodora , Mazzoccoli Carmela , De Luca Luciana , Petrucci Maria Teresa , Morabito Fortunato , Offidani Massimo , Di Raimondo Francesco , Falcone Antonietta , Omede' Paola , Tassone Pierfrancesco , Boccadoro Mario , Palumbo Antonio , Neri Antonino , Musto Pellegrino
Published: April 2023

PDF file - 122K, Boxplot distribution of NF-kB and proliferation indexes in the 21 PPCL and the 55 MM patients.
Supplementary Figure 1 from Pyrophosphorolysis-Activated Polymerization Detects Circulating Tumor DNA in Metastatic Uveal Melanoma
Authors: Madic Jordan , Piperno-Neumann Sophie , Servois Vincent , Rampanou Aurore , Milder Maud , Trouiller Bénédicte , Gentien David , Saada Stéphanie , Assayag Franck , Thuleau Aurélie , Nemati Fariba , Decaudin Didier , Bidard François-Clément , Desjardins Laurence , Mariani Pascale , Lantz Olivier , Stern Marc-Henri
Published: April 2023

PDF file, 32KB, Correlation between ctDNA and cfcDNA levels in UM patients.
Supplementary Figure 9 from Targeted Therapy for BRAFV600E Malignant Astrocytoma
Authors: Nicolaides Theodore P. , Li Huifang , Solomon David A. , Hariono Sujatmi , Hashizume Rintaro , Barkovich Krister , Baker Suzanne J. , Paugh Barbara S. , Jones Chris , Forshew Tim , Hindley Guy F. , Hodgson J. Graeme , Kim Jung-Sik , Rowitch David H. , Weiss William A. , Waldman Todd A. , James C. David
Published: April 2023

PDF file - 374K
Supplementary legend from Genotype-Specific Abnormalities in Mitochondrial Function Associate with Distinct Profiles of Energy Metabolism and Catecholamine Content in Pheochromocytoma and Paraganglioma
Authors: Rao Jyotsna U. , Engelke Udo F.H. , Rodenburg Richard J.T. , Wevers Ron A. , Pacak Karel , Eisenhofer Graeme , Qin Nan , Kusters Benno , Goudswaard Angelina G. , Lenders Jacques W.M. , Hermus Ad R.M.M. , Mensenkamp Arjen R. , Kunst Henricus P.M. , Sweep Fred C.G.J. , Timmers Henri J.L.M.
Published: April 2023

Supplementary legend
Supplementary Methods from Expression Profiling of Archival Tumors for Long-term Health Studies
Authors: Waldron Levi , Ogino Shuji , Hoshida Yujin , Shima Kaori , McCart Reed Amy E. , Simpson Peter T. , Baba Yoshifumi , Nosho Katsuhiko , Segata Nicola , Vargas Ana Cristina , Cummings Margaret C. , Lakhani Sunil R. , Kirkner Gregory J. , Giovannucci Edward , Quackenbush John , Golub Todd R. , Fuchs Charles S. , Parmigiani Giovanni , Huttenhower Curtis
Published: April 2023

PDF file - 80K
Supplementary Table 1 from Phase I Study of Vorinostat in Combination with Temozolomide in Patients with High-Grade Gliomas: North American Brain Tumor Consortium Study 04-03
Authors: Lee Eudocia Q. , Puduvalli Vinay K. , Reid Joel M. , Kuhn John G. , Lamborn Kathleen R. , Cloughesy Timothy F. , Chang Susan M. , Drappatz Jan , Yung W. K. Alfred , Gilbert Mark R. , Robins H. Ian , Lieberman Frank S. , Lassman Andrew B. , McGovern Renee M. , Xu Jihong , Desideri Serena , Ye Xiabu , Ames Matthew M. , Espinoza-Delgado Igor , Prados Michael D. , Wen Patrick Y.
Published: April 2023

PDF file, 80K, Supplementary Table 1: Temozolomide 150 mg/m2 Pharmacokinetic Parameters (first cycle).
Supplementary Tables 1 - 2 from Multisite Validation Study to Determine Performance Characteristics of a 92-Gene Molecular Cancer Classifier
Authors: Kerr Sarah E. , Schnabel Catherine A. , Sullivan Peggy S. , Zhang Yi , Singh Veena , Carey Brittany , Erlander Mark G. , Highsmith W. Edward , Dry Sarah M. , Brachtel Elena F.
Published: April 2023

PDF file, 85KB, Supplemental Table 1: Performance characteristics of the 92-gene assay for tumor subclassification. Supplemental Table 2: Pre-analytical variables and effects on 92-gene assay performance
Supplementary Figure 1 from Radioimmunotherapy of Fibroblast Activation Protein Positive Tumors by Rapidly Internalizing Antibodies
Authors: Fischer Eliane , Chaitanya Krishna , Wüest Thomas , Wadle Andreas , Scott Andrew M. , van den Broek Maries , Schibli Roger , Bauer Stefan , Renner Christoph
Published: April 2023

PDF file - 18K, Immunoprecipitation of huFAP from HT1080 FAP+ cells using anti-huFAP antibody
Supplementary Figure 7 from IL-17–Mediated M1/M2 Macrophage Alteration Contributes to Pathogenesis of Bisphosphonate-Related Osteonecrosis of the Jaws
Authors: Zhang Qunzhou , Atsuta Ikiru , Liu Shiyu , Chen Chider , Shi Shihong , Shi Songtao , Le Anh D.
Published: April 2023

PDF file - 116K, The potential positive feedback loop between Th17/IL-17 and M1 macrophages involved in bisphosphonate-related osteonecrosis of the jaws (BRONJ).
Supplementary Figure 3 from Tivantinib (ARQ197) Displays Cytotoxic Activity That Is Independent of Its Ability to Bind MET
Authors: Basilico Cristina , Pennacchietti Selma , Vigna Elisa , Chiriaco Cristina , Arena Sabrina , Bardelli Alberto , Valdembri Donatella , Serini Guido , Michieli Paolo
Published: April 2023

PDF File - 149K, MET exon 16 knock-out cells express a kinase-inactive MET protein.
Supplementary Figure 2 from Tivantinib (ARQ197) Displays Cytotoxic Activity That Is Independent of Its Ability to Bind MET
Authors: Basilico Cristina , Pennacchietti Selma , Vigna Elisa , Chiriaco Cristina , Arena Sabrina , Bardelli Alberto , Valdembri Donatella , Serini Guido , Michieli Paolo
Published: April 2023

PDF File - 269K, Tivantinib does not inhibit HGF-dependent or -independent MET auto-phosphorylation in U87-MG glioblastoma cells and NCI-H441 lung carcinoma cells.
Supplementary Figure 1 from Tivantinib (ARQ197) Displays Cytotoxic Activity That Is Independent of Its Ability to Bind MET
Authors: Basilico Cristina , Pennacchietti Selma , Vigna Elisa , Chiriaco Cristina , Arena Sabrina , Bardelli Alberto , Valdembri Donatella , Serini Guido , Michieli Paolo
Published: April 2023

PDF File - 183K, Analysis of c-MET gene copy number and MET protein expression in a panel of human tumor cell lines.
Supplementary Table 2 from Research-Based PAM50 Subtype Predictor Identifies Higher Responses and Improved Survival Outcomes in HER2-Positive Breast Cancer in the NOAH Study
Authors: Prat Aleix , Bianchini Giampaolo , Thomas Marlene , Belousov Anton , Cheang Maggie C.U. , Koehler Astrid , Gómez Patricia , Semiglazov Vladimir , Eiermann Wolfgang , Tjulandin Sergei , Byakhow Mikhail , Bermejo Begoña , Zambetti Milvia , Vazquez Federico , Gianni Luca , Baselga José
Published: April 2023

PDF file - 44K, Clinical-pathological comparison of the NOAH and the transNOAH gene expression (GEP) tumor samples.
Supplementary Figure 5 from Regulation of Colorectal Carcinoma Stemness, Growth, and Metastasis by an miR-200c-Sox2–Negative Feedback Loop Mechanism
Authors: Lu Yan-Xia , Yuan Li , Xue Xiao-Lei , Zhou Min , Liu Yan , Zhang Chao , Li Jing-Ping , Zheng Lin , Hong Min , Li Xue-Nong
Published: April 2023

PDF file - 842KB, Showd the sphere-forming capacity of HCT116 and SW480 cells, and the expression of miR-200c and Sox2 in in CRC cells transfected with Sox2 followed by the transfection of miR-200c.
Supplementary Methods, Figure Legends from Research-Based PAM50 Subtype Predictor Identifies Higher Responses and Improved Survival Outcomes in HER2-Positive Breast Cancer in the NOAH Study
Authors: Prat Aleix , Bianchini Giampaolo , Thomas Marlene , Belousov Anton , Cheang Maggie C.U. , Koehler Astrid , Gómez Patricia , Semiglazov Vladimir , Eiermann Wolfgang , Tjulandin Sergei , Byakhow Mikhail , Bermejo Begoña , Zambetti Milvia , Vazquez Federico , Gianni Luca , Baselga José
Published: April 2023

PDF file - 119K
Supplementary Figure 3 from Regulation of Colorectal Carcinoma Stemness, Growth, and Metastasis by an miR-200c-Sox2–Negative Feedback Loop Mechanism
Authors: Lu Yan-Xia , Yuan Li , Xue Xiao-Lei , Zhou Min , Liu Yan , Zhang Chao , Li Jing-Ping , Zheng Lin , Hong Min , Li Xue-Nong
Published: April 2023

PDF file - 365KB, Showed that the up-regulation of Sox2 promoted cell proliferation, migration and invasion in vitro.
Supplementary Figure Legends from FOXM1 Promotes the Warburg Effect and Pancreatic Cancer Progression via Transactivation of LDHA Expression
Authors: Cui Jiujie , Shi Min , Xie Dacheng , Wei Daoyan , Jia Zhiliang , Zheng Shaojiang , Gao Yong , Huang Suyun , Xie Keping
Published: April 2023

PDF file - 75KB
Supplementary Figure 3 from FOXM1 Promotes the Warburg Effect and Pancreatic Cancer Progression via Transactivation of LDHA Expression
Authors: Cui Jiujie , Shi Min , Xie Dacheng , Wei Daoyan , Jia Zhiliang , Zheng Shaojiang , Gao Yong , Huang Suyun , Xie Keping
Published: April 2023

PDF file - 221KB, Supplementary Fig. S3. Expression of FOXM1 and LDHA and their direct association with clinicopathological parameters in TMA-P.
Supplement Figure 4 from Germline Variants and Advanced Colorectal Adenomas: Adenoma Prevention with Celecoxib Trial Genome-wide Association Study
Authors: Wang Jiping , Carvajal-Carmona Luis G. , Chu Jen-Hwa , Zauber Ann G. , Kubo Michikai , Matsuda Koichi , Dunlop Malcolm , Houlston Richard S. , Sieber Oliver , Lipton Lara , Gibbs Peter , Martin Nicholas G. , Montgomery Grant W. , Young Joanne , Baird Paul N. , Ratain Mark J. , Nakamura Yusuke , Weiss Scott T. , Tomlinson Ian , Bertagnolli Monica M.
Published: April 2023

Supplement Figure 4