bluuebunny/crossref_metadata_2025 huggingface dataset:
Host Plants Shape the Codon Usage Pattern of Turnip Mosaic Virus
Authors: Qin Lang , Ding Shiwen , Wang Zhilei , Jiang Runzhou , He Zhen
Published: October 2022

Turnip mosaic virus (TuMV), an important pathogen that causes mosaic diseases in vegetable crops worldwide, belongs to the genus Potyvirus of the family Potyviridae. Previously, the areas of genetic variation, population structure, timescale, and migration of TuMV have been well studied. However, the codon usage pattern and host adaptation analysis of TuMV is unclear. Here, compositional bias and codon usage of TuMV were performed using 184 non-recombinant sequences. We found a relatively stable change existed in genomic composition and a slightly lower codon usage choice displayed in TuMV protein-coding sequences. Statistical analysis presented that the codon usage patterns of TuMV protein-coding sequences were mainly affected by natural selection and mutation pressure, and natural selection was the key influencing factor. The codon adaptation index (CAI) and relative codon deoptimization index (RCDI) revealed that TuMV genes were strongly adapted to Brassica oleracea from the present data. Similarity index (SiD) analysis also indicated that B. oleracea is potentially the preferred host of TuMV. Our study provides the first insights for assessing the codon usage bias of TuMV based on complete genomes and will provide better advice for future research on TuMV origins and evolution patterns.
Development of Single-Cell Transcriptomics and Its Application in COVID-19
Authors: Wang Chaochao , Huyan Ting , Zhou Xiaojie , Zhang Xuanshuo , Duan Suyang , Gao Shan , Jiang Shanfeng , Li Qi
Published: October 2022

Over the last three years, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related health crisis has claimed over six million lives and caused USD 12 trillion losses to the global economy. SARS-CoV-2 continuously mutates and evolves with a high basic reproduction number (R0), resulting in a variety of clinical manifestations ranging from asymptomatic infection to acute respiratory distress syndrome (ARDS) and even death. To gain a better understanding of coronavirus disease 2019 (COVID-19), it is critical to investigate the components that cause various clinical manifestations. Single-cell sequencing has substantial advantages in terms of identifying differentially expressed genes among individual cells, which can provide a better understanding of the various physiological and pathological processes. This article reviewed the use of single-cell transcriptomics in COVID-19 research, examined the immune response disparities generated by SARS-CoV-2, and offered insights regarding how to improve COVID-19 diagnosis and treatment plans.
Plausible Differences between the Laboratory and Prototype Behaviors of Spillway Aerator Flows
Authors: Yang James , Li Shicheng , Lin Chang
Published: October 2022

An aerator, installed to prevent cavitation damages in spillways and outlet works, generates a typical two-phase flow affected by its configuration and flow conditions. The major parameters of concern include air demand, jet trajectory and streamwise changes of air concentration near chute bottom. This study reviews the theoretical basis and deals with several aspects of physical scale modeling, supported exclusively by field measurements. Analyses reveal that the sub-atmospheric pressure generated in the air cavity should also be scaled in physical modeling, which is seldom the case in the laboratory environment. Thus, the conventional approach to upscale the air demand is controversial. With the data from both fields and laboratories, it is demonstrated that a direct conversion of air flow from model to prototype is justified only if the approach flow velocity in the model exceeds 7.0–7.5 m/s or the Reynolds number exceeds 1.58 × 106. Failing to meet this premise would bring about errors for prototype predictions; the error extent depends on both model scale and flow magnitude. In terms of cavity pressure drop, the prototype differs by a factor of less than 10 from its scale model with sufficient air supply. In a model, the air concentration along the chute bottom drops considerably within one to two trajectory lengths. The prototype differs from its model in such a way that the air concentration decay is much slower, with a higher level that is maintained over a longer distance downstream of the impact location. This study is intended to provide insight for laboratory studies and engineering design.
Measurement of Coastal Marine Disaster Resilience and Key Factors with a Random Forest Model: The Perspective of China’s Global Maritime Capital
Authors: Sui Xiaotong , Hu Mingzhao , Wang Haoyun , Zhao Lingdi
Published: October 2022

Frequent outbreaks of marine disasters in the context of global warming pose a serious threat to the sustainable development of coastal areas and the construction of global maritime capitals. Implementing integrated marine and coastal management and assessing and enhancing cities’ resilience to marine disasters are of practical importance. Based on the capital perspective, this study innovatively constructed a framework for the Coastal Marine Disaster Resilience Index (CMDRI) for the coastal city level, considering the main marine disaster characteristics of Chinese coastal areas. Eight coastal cities in China proposed to build global maritime capitals were used as research objects. The random forest model, which can handle complex nonlinear systems and feature importance, was applied for the first time to resilience assessment and key factor identification in marine disasters. The results show that the overall level of CMDRI of each city is steadily increasing, with Shenzhen having the highest marine disaster resilience grade for each year and Zhoushan having the lowest. Economic and human capitals accounted for a more significant proportion of key factors, followed by physical and social capitals, and environmental capital accounted for a minor proportion. The comparison results of model performance show that the random forest model has better fitting accuracy and stability in assessing CMDRI and can be further applied to other disaster resilience and sustainability areas.
Analysis of dental status in children with type I diabetes mellitus: a literature review
Authors: Chuykin S. V. , Akatyeva G. G. , Malievsky O. A. , Makusheva N. V. , Bayburina E. K. , Kuchuk K. N. , Chuykin G. L. , Petrova E. A.
Published: October 2022

Relevance. Diabetes mellitus is one of the most complex metabolic chronic diseases. Severe forms of type I diabetes mellitus are more common in children and adolescents, and its prevalence is increasing in many countries. Type I diabetes mellitus in children and adolescents remains an essential health issue in many countries despite the achieved scientific and practical results and progress in diabetology. Therefore, its early detection in children is still relevant and is associated with the early diagnosis of endocrinolog ical pathologies.

Materials and methods. The study searched the publications in PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses), Medline (www.elibrary.ru, www.ncbi.nlm.nih.gov/pubmed) by the specific keywords.

Results. In children with diabetes mellitus, vascular changes in periodontal tissues appear earlier than in other organs. On oral examination of children with diabetes mellitus, 50% of cases reveal periodontal lesions, and the lesions are often in the areas of the lower molars. If not treated, the following perio-dontitis signs are present in diabetic children: bleeding of the gingival papillae and the bright red colour of the gingival margin. There may be bulging of granulations from pathological gingival pockets. In most patients with type I diabetes mellitus, cytology of the periodontal pockets and gingival sulci demonstrated inflammatory cytologic responses, changes in the stratified squamous epithelium, and mixed bacterial microflora with leukocytes and erythrocytes.

Conclusion. The study of type I diabetes mellitus impact on pathological changes in the oral cavity of children and the development of therapeutic and preventive measures is a relevant issue in pediatric dentistry, which justifies the need to continue research in this area.
Results of orthodontic treatment of permanent upper incisors intrusive luxation: a clinical case
Authors: Simakova A. A. , Gorbatova L. N. , Gorbatova M. A. , Goldberg M. A. , Podrezova A. V. , Popov V. A.
Published: October 2022

Relevance. Dental trauma prevalence is high among children. Treatment of intrusive luxation, where the choice of treatment technique depends on the root formation stage, is of particular interest.

Clinical case description. The article presents the treatment results of an 8-year-old patient with mixed dentition. The patient was diagnosed with an intrusive luxation of teeth 1.1, 2.1, soft tissue contusion, and fracture of the maxillary alveolar process.

Thirteen days after the injury, we started the orthodontic treatment with a bracket system (ROTH 018 Micro-Sprint) placed on the upper teeth, controlled by cone-beam computed tomography (CBCT). Arches and elastics were consecutively changed during the treatment. In nine and a half months, teeth 1.1 and 2.1 were extruded. Functional and aesthetic parameters were restored. We assessed stability of the obtained result 18 months after the start of orthodontic treatment.

Conclusion. The intrusive luxation treatment planning calls for a thorough history and diagnosis data comparison. The choice of non-surgical treatment without tooth extraction requires informing the patient about possible complications, treatment difficulties and long-term follow-up observation. The successful treatment outcome needs comprehensive patient management by a multidisciplinary team of a maxillofacial surgeon, pediatric dentist, orthodontist and other related specialists, if necessary.
КОРУПЦІЯ В ПУБЛІЧНОМУ УПРАВЛІННІ ЯК ПЕРЕПОНА ПЕРЕХОДУ СУСПІЛЬСТВА ДО ІНДУСТРІЇ 4.0
Authors: Shpak Yuryi , Dragan Ivan
Published: October 2022

Перехід до Індустрії 4.0 передбачає використання інноваційного потенціалу, який також визначається інституційним середовищем, зокрема рівнем корупції та її сприйняттям. Посткомуністичні країни Центральної та Східної Європи характеризуються вищим рівнем корупції та більшою часткою тіньової економіки, що може фундаментально знизити їхній інноваційний потенціал і таким чином стати гальмом переходу до Індустрії 4.0. Таким чином, мета цієї статті полягає в тому, щоб оцінити вплив корупції в державному управлінні на розмір і структуру тіньової економіки, а також визначити, чи може наявність корупції вплинути на перехід країни та суспільства до Індустрії 4.0. У статті  встановлено, що корупція в державному управлінні має набагато більш руйнівний і довгостроковий вплив на накопичення капіталу, ніж на чисельність робочої сили. У цьому сенсі корупція може стати суттєвою перешкодою для переходу, підкреслюючи, що завдання державної політики полягає не лише в підтримці цифровізації, роботизації та подальшого розвитку технологій, але особливо в забезпеченні прозорого некорупційного середовища державного управління.
Vulneración a la seguridad jurídica y legalidad en la aplicación del convenio de pago
Authors: Silva-Vargas Andersson Junior , Ormaza-Ávila Diego Adrián
Published: October 2022

El presente trabajo se enfoca en analizar y determinar las vulneraciones al derecho de seguridad jurídica y principio de legalidad en la contratación pública derivadas de las actuaciones administrativas implementadas en el procedimiento de suscripción de convenios de pagos “por parte del Instituto Ecuatoriano de Seguridad Social”.  De alcance metodológico descriptivo. Entre los resultados obtenidos se determina que la falta de normas y “disposiciones jurídicas previas, claras y públicas” sobre el convenio de pago influyen sustancialmente en errores y falencias administrativas, en la inobservancia y elución de los procedimientos previstos en la LOSNCP, provocando grandes pérdidas económicas el erario fiscal. Consecuentemente, es vital prescindir de las disposiciones que dan fundamento al ilegal acto administrativo que permite reconocer las obligaciones pendientes de pago mediante el convenio de pago.
Recurso de apelación y derecho a la defensa frente a las contravenciones de tránsito
Authors: Arévalo-Vázquez Edwin Alfredo , Valle-Franco Alex Iván
Published: October 2022

El estudio se planteó como objetivo analizar el recurso de apelación y derecho a la defensa frente a las contravenciones de tránsito no privativas de libertad. La metodología aplicada partió de un estudio con alcance descriptivo y de diseño no experimental, se acudió para el análisis al método analítico-sintético y la técnica aplicada fue el estudio de casos y la revisión bibliográfica, utilizando para ello las bases de datos científicas. Con lo expresado en esta norma legal, se atenta a la garantía de la impugnación consagrada en el literal m, numeral 7 del artículo 76 de la Constitución, así como lo normado en la Convención Americana de Derechos Humanos, el cual refiere a las garantías como la de recurrir ante un órgano jurisdiccional superior.
Derecho constitucional para la integración latinoamericana
Authors: Atencio-González Rously Eedyah
Published: October 2022

Derecho constitucional para la integración latinoamericana
Aumenta um ponto quem conta um conto?
Authors: Pereira Nathalia Augusto
Published: October 2022

Resenha de Agora serve o coração, de Nei Lopes (Record, 2020).
Outro defunto autor na literatura brasileira: masculinidades e relato pós-morte em Cloro, de Alexandre Vidal Porto
Authors: Silva Junior Cloves da
Published: October 2022

Este artigo analisa as semelhanças e diferenças entre o defunto autor Constantino Curtis do romance Cloro, de Alexandre Vidal Porto (2018), e o defunto autor já consagrado de Machado de Assis (2014), em Memórias póstumas de Brás Cubas, com ênfase na primeira obra. Na primeiras seção do artigo a análise está centrada, especificamente, nos aspectos temáticos relativos à adequação a um padrão de masculinidade e na composição do kit de homem de bem por parte de Constantino, diferentemente de Brás Cubas que representa aquilo que a sociedade espera de um homem. Na segunda seção, destaca-se os aspectos formais que envolvem o relato pós-morte dos dois defuntos autores. Trata-se de uma pesquisa bibliográfica a partir do suporte teórico de Bourdieu (2012), Connell e Pearse (2015), Dalcastagnè (2012), Ginzburg (2012), dentre outros. Ao final do trabalho, compreende-se que o relato pós-morte, para Constantino, significa muito mais do que a liberdade de falar: é aceitação de si próprio e a análise acurada de uma vida protocolar.
Ana de Santana: uma poética em quatro flashes
Authors: Ramalho Christina Bielinski
Published: October 2022

Ana de Santana, poeta nascida em Caicó, Rio Grande do Norte, publicou quatro livros de poemas: Danaides: inventário de signos, de 2005; Em nome da pele, de 2008; À unha, de 2016; e o recém-lançado Bicicletas para descer ladeiras à noite, obras que, em conjunto, apresentam uma trajetória poética marcada por signos reveladores de uma aguda cons- ciência estética, filosófica e social, que ora nos levam ao universo meta- linguístico e intertextual que caracteriza sua poética, ora a conteúdos finamente sustentados nos apelos temáticos da contemporaneidade, com destaque para questões de gênero e reflexões filosóficas. Esta abordagem pretende, à luz de Affonso Ávila, Giorgio Agamben e Ya- netsy Pino Reina, e de um diálogo direto com a poeta, discorrer sobre o modo como as obras articulam, individualmente, os polos metalin- guagem, intertextualidade, questões de gênero e reflexões filosóficas, de forma a reconhecermos o percurso estético e conceitual da poesia de Santana, flagrando permanências e inovações, de modo a compor um retrato que, costurando flashes, revele o impacto dessa presença norte-rio-grandense no cenário da poesia contemporânea brasileira.
MARJORIE PERLOFF: “A arte tem que mostrar a complexidade da época [...] O papel do crítico hoje em dia é encontrar vida na literatura, mostrar que ela cria outros mundos e é um convite à participação e ao conhecimento”
Authors: Ribas Bastos Laíse , De Oliveira Neto Godofredo
Published: October 2022

Entrevista realizada em outubro de 2021, durante o XI Encontro do Fórum de Literatura Brasileira Contemporânea da Universidade Federal do Rio de Janeiro. A professora e pesquisadora Marjorie Perloff foi a convidada da mesa de abertura do evento, realizado de modo remoto. Mediada pelos professores Godofredo de Oliveira Neto e Laíse Ribas Bastos, a conversa retoma momentos importantes do percurso de Marjorie Perloff no trabalho e na pesquisa com a poesia brasileira, passa pelo seu trabalho mais recente, Infrathin,desenvolvido a partir do pensamento de Marcel Duchamp, e reforça aspectos determinantes para a leitura de poesia hoje.
Trade secret as a factor of ensuring national economic security: the practice of China and the USA (part 2)
Authors: Androshchuk H. O.
Published: October 2022

The global economic and innovative impact of trade secrets is studied. Trade secrets have a broad reach and support the innovation ecosystem by protecting technological, product, market and organizational innovations, as well as providing a key complement and support to other intellectual property (IP). It is shown that misappropriation or theft of trade secrets from OECD countries is 1–3 % of GDP. The cost of trade secret theft has reached $ 1.7 trillion per year. On the example of the economy of China and the USA, the growing importance of intangible assets, commercial secrets and the increasing threats of their theft are shown. In the US, more than 80% of all economic espionage cases and 60 % of trade secret cases are related to China. Given their negative impact on national security, the US is applying new legislative mechanisms to protect IP and trade secrets. The challenges and risks associated with Ukraine’s cooperation with China are analyzed. Recommendations for their minimization and countermeasures against threats are given.
Potensi Pengaruh Radiasi Gelombang Elektromagnetik Telepon Seluler Terhadap Kesehatan
Authors: Yushardi Yushardi , Sudarti Sudarti , Hamdi Muhammad Najih
Published: October 2022

Pendahuluan: Telepon seluler pada saat ini sudah mengalami perkembangan, dengan beragam kemudahan yang dapat dilakukannya. Telepon seluler atau yang dikenal dengan smartphone atau ponsel pintar pada saat ini menghasilkan radiasi gelombang elektromagnetik yang berpengaruh terhadap kesehatan tubuh manusia.
Tujuan: Mengetahui pengaruh dari radiasi elektromagnetik telepon seluler terhadap kesehatan otak manusia.
Metode: Penelitian menggunakan Literatur Review tipe naratif, dengan menggunakan jurnal dan buku baik nasional maupun internasional. Radiasi elektromagnetik yang ditimbulkan dari penggunaan telepon seluler terindikasi dapat mempengaruhi beberapa gangguan terhadap kesehatan manusia.
Hasil: Indikasi gangguan kesehatan tersebut dapat berupa tumbuhnya tumor dan kanker pada otak, dapat meyebabkan stress, terganggunya sperma, glioma dan juga terganggunya sel darah merah. Gangguan yang disebabkan oleh radiasi elektromagnetik telepon seluler terhadap kesehatan masih menjadi polemik.
Kesimpulan: Radiasi elektromagnetik yang ditimbulkan dari penggunaan telepon seluler berpotensi dapat menyebabkan beberapa gangguan terhadap kesehatan.
Penatalaksanaan Batuk Efektif Akibat Tuberkulosis Paru
Authors: Rahman Irpan Ali
Published: October 2022

Pendahuluan: Tuberkulosis merupakan masalah kesehatan masyarakat di seluruh dunia, dengan Indonesia khususnya menjadi penyebab kematian kedua akibat penyakit menular.
Tujuan: Melaksanakan asuhan keperawatan secara komprehensif kepada klien yang mengalami gangguan system pernapasan akibat TB Paru dengan intervensi batuk efektif.
Metode: Desain penelitian menggunakan studi kasus, yang bertujuan menggambarkan fenomena dengan pendekatan asuhan keperawatan.
Hasil: Menunjukan klien mengatakan sering batuk pada malam hari, batuk berdahak, susah mengeluarkan dahak menjadi penyebab tersebut adalah TB Paru mengakibatkan infeksi primer pada alveoli mengakibatkan produksi sekret meningkat sehingga muncul masalah bersihan jalan nafas tidak efektif.
Kesimpulan: Optimalisasi menejemen jalan nafas dalam asuhan keperawatan tuberkulosis paru dengan bersihan jalan nafas tidak efektif.
Tingkat Pengetahuan Terhadap Ibu Hamil Resiko Tinggi Melalui Kompetensi Soft Skill dan Kinerja Petugas Kesehatan
Authors: Rukina Rukina , Pangastuti Dwi
Published: October 2022

Pendahuluan: membangunan kesehatan merupakan cara untuk meningkatkan kesadaran, kemauan dan kemampuan untuk hidup sehat bagi setiap orang sehingga tingkat kesehatan masyarakat yang optimal dapat tercapai.
Tujuan: mengetahui pengaruh tingkat pengetahuan terhadap ibu hamil resiko tinggi melalui kompetensi soft skill dan kinerja petugas kesehatan.
Metode: Penelitian kuantitatif yang dilaksanakan. Populasi penelitian adalah seluruh ibu hamil. Tehnik sampling adalah simple random sampling dengan rumus slovin sehingga sampel penelitian ini adalah 126 orang. Teknik pengumpulan data melalui observasi, kuesioner, wawancara dan dokumentasi, sedangkan teknik analisis data menggunakan path analysis.
Hasil: menunjukkan bahwa kehamilan resiko tinggi dapat ditangani dengan semakin baiknya tingkat pengetahuan, kompetensi soft skill dan juga kinerja tenaga kesehatan. Tingkat pengetahuan merupakan variabel yang memiliki pengaruh dominan terhadap kehamilan resiko tinggi yang ditunjukkan dengan tingginya advokasi dan pemberdayaan yang dilakukan oleh tenaga kesehatan dalam mendukung kualitas kehamilan.
Kesimpulan: bahwa kehamilan resiko tinggi dapat ditangani dengan semakin baiknya tingkat pengetahuan, kompetensi soft skill dan juga kinerja tenaga kesehatan. Meskipun demikian kompetensi soft skill dan juga kinerja tenaga kesehatan memberikan kontribusi yang baik dalam meningkatkan kualitas kehamilan
Analisis Kompres Air Hangat Sebagai Intervensi Gout Arthritis Dengan Masalah Nyeri Akut Pada Keluarga Lansia
Authors: Murwani Arita , Nuryati Nuryati , Hikmawati Anna Nur , Kusumasari RR Viantika , Amri Riza Yulina
Published: October 2022

Latar belakang Gout arthritis merupakan kelainan tulang metabolik yang disebabkan oleh metabolisme abnormal purin yang ditandai dengan meningkatnya kadar asam urat dalam darah sehingga menyebabkan nyeri pada persedian lokal. Salah satu terapi yang dapat digunakan untuk menurunkan skala nyeri pada pasien Gout arthritis yaitu kompres air hangat.
Tujuan menganalisis pengaruh pemberian kompres air hangat terhadap skala nyeri pada pasien Gout arthritis.
Metode yang digunakan adalah metode deskriptif dengan pendekatan studi kasus.
Hasil menunjukkan bahwa terdapat perbedaan skala nyeri sebelum dan sesudah pemberian kompres air hangat pada pasien Gout arthritis.
Kesimpulan bahwa kompres air hangat efektif untuk menurunkan skala nyeri pada pasien dengan Gout arthritis karena dapat mengurangi spasme otot, merangsang nyeri, menyebabkan vasodilatasi dan peningkatan aliran darah. Pembuluh darah akan melebar sehingga memperbaiki peredaran darah dalam jaringan tersebut.
Penerapan Sistem Menajemen Keselamatan dan Kesehatan Kerja
Authors: Nurfaizah Sitti , Risal M , Musfirah Musfirah
Published: October 2022

Pendahuluan: Sistem Manajemen Keselamatan serta Kesehatan Kerja merupakan bagian dari sistem manajemen risiko umum perusahaan yang mencangkup kebijakan dan komitmen, perencanaan, pelaksanaan, pengukuran serta evaluasi.
Tujuan: Untuk mengetahui pelaksanaan sistem manajemen keselataman dan Kesehatan kerja yang di terapkan di PT. Bosowa beton Indonesia apakah sesuai dengan Peraturan Pemerintah Republik Indonesia Nomor 50 Tahun 2012.
Metode: Jenis penelitian ini adalah penelitian kualitatif dengan pendekatan fenomenologis dengan informan berjumlah 9 orang.
Hasil: Menunjukkan bahwa penerapan SMK3 suda dilaksanakan berdasarkan PP No 50 Tahun 2012 yang mencangkup yang mencangkup kebijakan dan komitmen, perencanaan, pelaksanaan, pengukuran dan evaluasi. Serta pemantauan dan evaluasi.
Kesimpulan: dalam pelaksanaan SMK3 masi terdapat kendala mulai pengadaan APD yang sering kali terlambat, rendahnya budaya disiplin k3 serta lemahnya sangsi yang di berikan terhadap pekerja yang melanggar ketentuan. Serta kurangnya SDM yang berkompeten membuat pengawasan area kerja yang begitu luas tidak bisa di lakukan secara bersamaan
Status Gizi dan Faktor Lainnya dengan Produktivitas Kerja Tenaga Kerja Pada Masa Pandemi Covid-19
Authors: Simanungkalit Sintha Fransiske , Nasrulloh Nanang , Fatmawati Iin
Published: October 2022

Pendahuluan: Tenaga kerja merupakan setiap orang yang mampu melakukan pekerjaan guna menghasilkan barang dan/atau jasa baik untuk memenuhi kebutuhan sendiri maupun untuk masyarakat.
Tujuan: Mencari hubungan status gizi, riwayat penyakit, motivasi kerja dan displin kerja dengan produktivitas kerja pada masa pandemic Covid-19.
Metode: Jenis penelitian ini menggunakan desain penelitian potong lintang. Populasi penelitian ini adalah seluruh tenaga kerja non dosen dan sampel dalam penelitian ini sebanyak 30 orang.
Hasil: Uji bivariat didapatkan ada hubungan status gizi (p=0.03), motivasi kerja (p=0.04) dengan produktivitas kerja.
Kesimpulan: Bahwa seseorang dengan status gizi yang normal, motivasi kerja yang baik dan disiplin kerja yang baik dapat memperbaiki produktivitas kerja tenaga kerja. Perusahaan disarankan untuk memperhatikan status gizin motivasi kerja dan disiplin kerja.
Analisis Faktor Risiko Anemia dalam Kehamilan pada Masa Pandemi Covid-19
Authors: Arnianti Arnianti , Adeliana Adeliana , Hasnitang Hasnitang
Published: October 2022

Pendahuluan: Anemia menjadi salah satu faktor penyebab kematian ibu secara tidak langsung. Anemia dalam kehamilan merupakan kondisi ibu dengan kadar hemoglobin ibu kurang dari 11,0 g/dL pada trimester pertama dan ketiga serta kadar hemoglobin kurang dari 10,5 g/dL pada trimester kedua.
Tujuan: Mengetahui faktor yang mempengaruhi anemia dalam kehamilan pada masa pandemi Covid-19.
Metode: Penelitian ini menggunakan studi observasional analitik dengan desain studi kasus-kontrol. Metode pengambilan sampel menggunakan teknik Purposive Sampling. Besar sampel dalam penelitian ini adalah 99 sampel yang terdiri dari 33 kasus dan 66 kontrol. Data diperoleh dari tiga puskesmas yang berada di Kota Palopo yaitu, Puskemas Bara Permai, Puskemas Benteng, Puskesmas Wara Selatan.
Hasil: Analisis statistik didapatkan umur ibu hamil (OR=7,368; sig (0,000 < 0,05), paritas (OR=2,754; sig=0,047 < 0,05), jarak kehamilan (OR=2,925; Sig-p=0,022), pendidikkan (OR=3,750; sig-p=0,003), kepatuhan mengkonsumsi tablet Fe (OR=4,214; Sig-p=0,006, dan status LiLA (OR=27,125; Sig-p=0,000).
Kesimpulkan: Bahwa terdapat pengaruh yang bermakna antara umur ibu hamil, paritas, jarak kehamilan, pendidikan, kepatuhan konsumsi tablet Fe dan Status LiLA terhadap anemia dalam kehamilan.
Relaksasi Otot Progresif Menurunkan Tekanan Darah Pasien Hipertensi
Authors: Basri Muhammad , Rahmatia Sitti , K Baharuddin , Oktaviani Akbar Nur Afni
Published: October 2022

Pendahuluan: Hipertensi atau tekanan darah tinggi saat ini masih menjadi masalah kesehatan yang dialami oleh penduduk dunia terutama di Indonesia. Hipertensi atau tekanan darah tinggi merupakan peningkatan tekanan darah sistolik ≥140 mmHg dan tekanan darah diastole ≥ 90 mmHg saat dilakukan pemeriksaan sebanyak 2 kali dengan rentang waktu 5 menit dalam keadaan tenang.Salah satu cara untuk menurunkan tekanan darah pada pasien hipertensi adalah dengan melakukan relaksasi otot progresif.
Tujuan: Penelitian ini bertujuan untuk menjelaskan relaksasi otot progresif dalam menurunkan tekanan darah pada pasien hipertensi.
Metode: Metode yang digunakan adalah metode pengambilan dan pengumpulan data yang diilakukan melalui studi pustaka dengan melakukan penelurusan dari hasil publikasi ilmiah dengan rentang waktu 2017-2022 melalui database Google Scholar, Pubmed dan Researchgate.
Hasil: Relaksasi otot progresif dapat dilakukan secara terus menerus minimal 2 kali sehari selama 25-30 menit.
Kesimpulan: Relaksasi otot progresif ini sebaiknya dilakukan dengan benar seperti benar urutan, benar gerakan, dan dilakukan dengan fokus sehingga individu yang melakukan relaksasi otot progresif benar-benar mendapatkan perasaan rileks. Relaksasi otot progresif dapat dilakukan secara mandiri maupun dikombinasikan dengan teknik non-farmakologi lainnya.
Kebijakan dan Upaya Progresif dalam Penanggulangan Stunting pada Balita
Authors: Fakhruddin Sulfianti , Sari Andi Muti’ah
Published: October 2022

Pendahuluan: Stunting adalah kondisi gagal tumbuh pada anak balita akibat kekurangan gizi kronis yang ditandai dengan panjang atau tinggi badannya berada di bawah standar.
Tujuan: Mengetahui kebijakan dan upaya progresif dalam penanggulangan stunting pada balita.
Metode: Penelitian kualitatif dengan jumlah infoman sebanyak 16 orang, yang terdiri infoman biasa dan informan kunci.
Hasil: Menunjukkan bahwa upaya pogresif dalam penanggulangan stunting masih sangat minim karena pengetahuan, pola asuh maupun peran petugas masih sangat rendah.
Kesimpulan: Bahwa upaya progresif penanggulangan stunting masih perlu ditingkatkan mengenai pengetahuai ibu mengenai makanan yang sehat dan bergizi untuk diberikan kepada balita. Pengambil kebijakan agar berperan proaktif dalam memerangi stunting baik melalui edukasi, konseling maupun pemberdayaan kepada ibu balita agar mereka bisa memahami penyebab maupun resiko apabila anaknya menderita stunting.
Gejala Depresi pada Lanjut Usia di Masa Pandemi Covid-19
Authors: Kusuma Made Dian Shanti , Ayu Yuliati Darmini Anak Agung
Published: October 2022

Pendahuluan: Dampak Corona Virus Diseases (Covid-19) pada lansia tidak hanya mengarah pada masalah kesehatan fisik namun juga masalah psikologis yang dapat menyebabkan lansia memiliki gejala depresi.
Tujuan: mengetahui prevalensi gejala depresi lansia serta faktor yang mempengaruhi tanda dan gejala depresi lansia di masa pandemi Covid-19.
Metode: Tinjauan ini menggunakan pendekatan literature review yang menggunakan sumber data dari Google scholar, PubMed dan ProQuest. Kemudian ditemukan hasil penelusuran artikel sebanyak 17,323 yang kemudian dilakukan penyaringan berdasarkan kriteria inklusi, 14 artikel yang ditelaah dalam penelitian ini.
Hasil: Rentang prevalensi pada lansia diperoleh hasil dengan rentang 7.7 % - 62.3%. lansia yang beresiko memiliki gejala depresi adalah lansia dengan kelompok usia lebih tua ≥ 75 tahun, lansia yang tinggal sendiri, merasa kesepian, kurangnya kontak sosial baik dengan keluarga dan teman, serta lansia yang memiliki penyakit penyerta atau komorbiditas. Prevalensi lansia yang memiliki penyakit penyerta atau komorbiditas adalah sebanyak 61%.
Kesimpulan: Berdasarkan hasil studi literatur ini dapat menjadi dasar dalam pemberian intervensi pada lansia yang beresiko memiliki gejala depresi, sehingga lansia dapat mencapai kesejahteraan fisik serta psikologis yang diharapkan
Perbedaan Tingkat Kecemasan Primigravida dan Multigravida Trimester III dalam Menghadapi Persalinan
Authors: Halman Dian Pratiwi , Umar Syaniah , Limbong Theresia
Published: October 2022

Pendahuluan: Kehamilan merupakan salah satu ekspresi perwujudan diri sebagai calon ibu dan ayah. Wanita yang hamil mengalami kecemasan tentang berbagai masalah dari satu trimester ke trimester selanjutnya. Kecemasan berubah seiring dengan semakin tua umur kehamilan.
Tujuan: Mengetahui adanya perbedaan kecemasan antara ibu hamil primigravida dan multigravida pada kehamilan trimester III.
Metode: Penelitian ini menggunakan metode pendekatan cross sectional dengan menggunakan teknik consecutive sampling. Pengumpulan data dilakukan dengan mengisi kuesioner karakteristik responden dan kuesioner HRS-A.
Hasil: Uji chi-square usia 0,426; pendidikan 0,567; pekerjaan 0,224; dan penghasilan 0,132; sementara kelompok multigravida terdiri atas usia 0,620; pendidikan 0,582; pekerjaan 0,594; dan penghasilan 0,05.
Kesimpulan: Bahwa usia, pendidikan, pekerjaan dan penghasilan tidak berpengaruh terhadap perbedaan tingkat kecemasan ibu hamil, terdapat perbedaan yang signifikan terhadap tingkat kecemasan ibu hamil primigravida dan multigravida trimester III.
Novel method to visualize Preston’s coefficient distribution for chemical mechanical polishing process
Authors: Hashimoto Yohei , Furumoto Tatsuaki , Sato Takumi , Suzuki Norikazu , Yasuda Hozumi , Yamaki Satoru , Mochizuki Yoshihiro
Published: October 2022

Preston’s law is widely used in polishing simulations in which the distribution of Preston’s coefficients on an entire wafer surface is generally assumed to be uniform. However, it is more likely that the distribution is not uniform and depends on several factors. To clarify Preston’s coefficient distribution in chemical mechanical polishing (CMP), we propose a novel experimental technique. In the proposed method, the unique experimental approach “stop polishing,” where the wafer does not rotate, and thus the circumferential variation of the coefficient is not averaged, is applied. Oxide-CMP experiments verified the uneven Preston’s coefficient distribution depending on the distance from the pad rotation center. Furthermore, we investigated the influence of slurry supply position on Preston’s coefficient distribution, and clarified that the distribution depends on slurry flow condition. Therefore, the proposed method is expected to be a novel tool for analyzing the CMP process from the perspective of Preston’s coefficient distribution.
BEYOND THE BOUNDARIES: UNDERSTANDING BUDDHIST DEVELOPMENT FROM ORIENT TO OCCIDENT WITH REFERENCE TO ITALY AND DANTE
Authors: Prakash Satyajeet
Published: October 2022

On the viewpoint of topographical location Orient and Occident are two sides of the globe.Socially,culturally,linguistically,
traditionally, politically, philosophically and psychologically both are two entirely different entities. Rudyard Kipling wrote
the poem titled 'The Ballad of East and West' in which he said “Oh, East is East, and West is West, and never the twain shall
meet”(Jouhki,2006,p 01).However,when the matter of meditation,religion,spirituality,devotion,high spirits,deep feelings
and beliefs etc.arises it is observable that Occident tends to go in line with Orient.But unfortunately due to false beliefs both
eastern and western scholars took no importance of East on the West and it has been made to notice that only Orient has
learnt from the Occident.Kipling expressed further “But there is neither East nor West,Border,nor Breed,nor Birth,When two
strong men stand face to face, tho' they come from the ends of the earth!” (Jouhki, 2006, p 15).The present paper tries to
explore the influence of Orient to Occident especially in the frame of the reference of Buddhism
THE IMPORTANCE OF RECOGNIZING THE ACUTE COMPLICATIONS OF RHINOSINUSITIS: A CASE REPORT
Authors: Cardoso Taina Maia
Published: October 2022

The difficulty in establishing an early diagnosis in the face of
intracranial complications of rhinosinusitis can cause
significant clinical changes and irreversible sequelae.
Politische Ideen im Wandel der Zeit
Authors: von Alemann Ulrich , Basedahl Nina , Graeßner Gernot
Published: October 2022

Von Sokrates und Platon bis zu Jürgen Habermas und Chantal Mouffe: Dieses Buch bietet eine umfangreiche Übersicht politischer Ideen aus verschiedenen Epochen von der Antike bis hin zur Gegenwart. Im Einklang mit dem Lebensweg der Denker:innen werden ihre Theorien ebenso wie ihre Wirkung im ideengeschichtlichen Kontext aufgezeigt und miteinander verglichen. Zudem stellen die Autor:innen Bezüge zu aktuellen politischen Diskursen her: Demokratietheorie, Identitätspolitik, Freiheit und Gerechtigkeit sowie Toleranz und Streitkultur. Durch die didaktische Aufbereitung des Materials mit Kästen, Übungen und Reflexionsfragen ist dieses Buch ein optimaler Begleiter für den Einstieg in die politische Theorie.
Multi-key Fully Homomorphic Encryption without CRS from RLWE
Authors: Luo Fucai
Published: October 2022

Fully Homomorphic Encryption (FHE) is a powerful encryption system in cloud computing that allows homomorphic computations on encrypted data without decrypting them. Multi-key fully homomorphic encryption (MFHE), as an extension to FHE, allows homomorphic computations on ciphertexts encrypted under different keys.   However, most MFHE schemes require a Common Random\slash Reference String (CRS), while the few that do not are based on the Learning With Errors (LWE) problem, which means that they can only deal with single bit plaintext.  Consequently, MFHE schemes based on the Ring Learning With Errors (RLWE) problem are more desirable, as they can handle polynomial plaintext.  Requiring the CRS seems to weaken the semantic definition of MFHE, where all users generate their own keys independently.

In this paper, we study the RLWE-based MFHE in the CRS model and propose the first RLWE-based MFHE without CRS.   To this end, we remove the CRS by designing a new relinearization algorithm.  Like previous MFHE schemes, our RLWE-based MFHE without CRS has a simple 1-round threshold decryption, which implies a $3$-round secure MPC protocol in the plain model from the RLWE assumption.
Cyclical capitalization: basic models
Authors: D'Amato Maurizio , Cucuzza Giuseppe
Published: October 2022

The relevance of market cycles is known in the financial markets and in the context of real estate valuations it manifests itself in the estimate of the “exit value” of the Discounted Cash Flow Analysis. The hypothesis that the market cycle has a behaviour very similar to what happened in the past introduces some risks and uncertainty in the estimated value. To allow a more extensive use of cyclical capitalization in formulating value judgments, this paper proposes two methodological adaptations to the original model: the first, based on the presence of a regular market trend; the second based on the hypothesis of irregular market cycles and therefore more representative of the dynamics to which a specific real estate segment is exposed. In the perspective of a more extensive availability of information, data and extra-data, other application areas are also identified on which further investigations need to be developed.
Prospective, Retrospective, and Formal Division
Authors: Bergstra Jan Aldert
Published: October 2022

Division by zero is a controversial theme. Why is division by zero a relevant issue and how can this issue be  addressed from different perspectives? Fracterm is used as an abbreviation for fractional expression. Three types of occurrence of the division symbol in a fracterm are distinguished: prospective occurrence, retrospective occurrence, and formal occurrence. Mathematics mostly features retrospective occurrences of division, computer programming gives rise to prospective occurrences, and so does automated proof checking. The use of division in an axiom system may indicate the presence of formal occurrences of division symbols.
Contribución de las cooperativas de trabajo como estrategia de empleo ante el COVID-19 en Paraguay - año 2020
Authors: CAÑETE Clarissa Melina Rodríguez , BAÉZ Marcela Fernanda Achinelli
Published: October 2022

La investigación presenta las diferentes situaciones que se visibilizaron durante la pandemia Covid-19 en el mercado laboral paraguayo referente a la pérdida de puestos laborales, con énfasis en las cooperativas de trabajo como alternativa de generación de empleo. El objetivo general fue analizar la contribución de las cooperativas de trabajo como estrategia de empleo ante el Covid-19. La modalidad de investigación fue bibliográfica-documental, con enfoque cuantitativo. Para la estimación de la generación de empleo, a partir de la propuesta de cooperativas de trabajo, se tomó en cuenta la población económicamente inactiva, la población desempleada, la población dedicada al servicio doméstico, la estructura familiar y la conformación mínima de socios/as en las cooperativas de trabajo. Los resultados plantean tres escenarios de empleabilidad con la creación de las cooperativas de trabajo en los cuidados a infantes y adultos mayores. Una de las conclusiones plantea el potencial del sector de cuidados, la formalización de un sector de trabajo, la generación como alternativa laboral en las cooperativas de trabajo a desarrollarse en los diferentes sectores de la economía. Se sugiere el trabajo multisectorial del sector cooperativo y el Ministerio de Empleo Trabajo y Seguridad Social principalmente, para visibilizar el aporte de las entidades de la economía social.
A Lei Geral do Turismo no Brasil
Authors: Silva Juliana Ferreira da , Faria José Ricardo Vargas de , Gomes Bruno Martins Augusto
Published: October 2022

A Lei Geral do Turismo, Lei n.º 11.771/2008, é o marco normativo do turismo brasileiro. Dois projetos de lei (n.º 641/2011 e n.º 2.724/2015) propõem alterações à norma e à organização do turismo nacional. Com o objetivo de caracterizar a referida Lei e os projetos que buscam sua alteração, o artigo analisa, por meio de uma pesquisa descritiva, a Lei, os projetos e suas justificativas de alteração. O projeto n.º 641/2011 é uma proposta que busca punir meios de hospedagem que descumprirem o período de diária, enquanto o projeto n.º 2.724/2015 é um instrumento que estreita a relação entre os setores público e privado e aponta para a promoção de vantagens ao setor de negócios. Dada a relevância das alterações na Lei Geral do Turismo, argumenta-se a necessidade de ampliar o entendimento utilitário e econômico do turismo que aproxima a atividade principalmente aos interesses do setor privado.
Whether the Incumbent Development Policy Brings about Neo-Colonialism or Not in the Paradigm of Economy and Anthropology
Authors: Rahman Tahmidur , Jakaria S M
Published: October 2022

The highly metamorphosing world order, transforming stakeholders’ power dynamics & the provocations of post-modernization are unhackneyed horizons in the facet of development. Development is vastly conceded in sociological paradigm because of its inherent momentous affiliation in the society. The propensity of development currently presumes not only economic germination but also it has been considered through the sanctuary of ambient eco- friendly environment, holistic livelihood slant and sharing the yield of technological headway & empirically valued modern erudition. These indispensable strands sometimes exhibit the reciprocal repercussion of intended development. The staunch domains are attempting to subjugate the feeble one. Functionally development is extremely agile & overcoming the scarcity in its passage by any means. So eventually it has been inflicted to overlook the comprehensive well-being of human. In modern era, incumbent development revamps the adrift colonialism which once has been contemplated to be abrogated. So, neo-colonialism perhaps is regarded as the altercation in the development discourse.
Persistently Augmented FGF-23 Serum Values in a Surgically Resolved Oncogenic Osteomalacia Patient with No Tumor and Inflammatory Activity
Authors: Hernández-Martínez Claudia , Montaño Luis F. , Vergara-Lopez Alma
Published: October 2022

Objective: Oncogenic osteomalacia is a paraneoplastic syndrome characterized by severe hypophosphatemia, hyperphosphaturia, and osteomalacia subordinated to renal loss of phosphate. It is caused by overproduction of phosphatonin fibroblast growth factor-23 by benign mesenchymal tumors which, when surgically eliminated, returns to basal levels. Methods: We report a case of a patient with oncogenic osteomalacia from a sacrum mesenchymal tumor whose FGF-23 levels remain elevated two years after successful surgical treatment. Results: A 53-year-old man with severe difficulty to walk and stand, severe hypophosphatemia, hyperphosphaturia, and raised levels of alkaline phosphatase and FGF-23 was diagnosed with oncogenic osteomalacia after a thorough process of elimination of causes of hyphosphatemia were excluded. Despite systemic chemotherapy, surgical removal of sacrum, primary mesenchymal tumor, phosphate and calcium supplementation, and no evidence of tumor recurrence, the serum concentration of FGF-23 remains elevated two years after discharge. Conclusions: The possible underlying mechanisms of sustained FGF-23 serum concentrations in this patient suggest the presence of molecular alterations in the FGF/FGFR signaling pathway.
Literature Review: Drug Therapy in Ischemic Stroke Patients
Authors: Safira Nabila , 'Azam Muhammad Tholhah
Published: October 2022

Background: Ischemic stroke is the foremost common cause of stroke around the world, bookkeeping for 10 times more strokes than hemorrhagic strokes in higher pay nations. There are proof accessible for each antiplatelet sedate utilized in the treatment of ischemic stroke. The advertised recommendations for elective restorative choices when confronted with repetitive stroke. Aim: To know the use of antiplatelet in ischemic stroke patients. Method: This study used a systematic review that searched using the keyword Antiplatelet and Ischemic Stroke in Google Scholar, Crossref, and PubMed. Recent studies in English published in 2012-2022. Result: After the final screening, the author analyzed 4 articles that were published after the year 2012. Conclusion: In spite of the fact that great proof exists for the utilization of certain antiplatelet operators for postischemic stroke, there are significant openings for future investigation to examine personalized treatments. These incorporate screening patients for platelet polymorphisms that bestow antiplatelet resistance and for randomized trials counting more racially different populations.
A Study of Old Age Delirium and Quality of Life of Family Caregivers
Authors: J Dr. Nimitha K , Thomas Dr. Jini
Published: October 2022

Objectives: To study the aetiology of patients of delirium in old age, to study the severity of delirium in old age and to study the quality of life of family caregivers of delirium patients. Design: Prospective, observational, and cross sectional. Setting: Inpatient tertiary care hospital setting. Participants: Subjects with the diagnosis of Delirium qualifying according to ICD-10 (international classification of disease-10) and confirmed with CAM scale aged >60 years and Patient or patient’s family members willing to give consent. Measurements: Socio-demographic questionnaire, Confusion assessment method, Delirium index, Delirium aetiology check list, ICD -10 DCR, WHO QOL BREF and the Barthel index. Results: There is no significant association between delirium severity and WHOQoL. There is no significant association between Barthel index and WHOQoL. There is no significant association between WHOQoL and delirium aetiologies. There is no significant association between gender and WHOQoL. There is no significant association between marital status and WHOQoL. There is no significant association between religion and WHOQoL. There is no significant association between WHOQol and education. There is significant association between WHOQoL and occupation. Emloyed subjects have better quality of life than unemployed. There is no significant association between WHO QoL and residence. There is no significant association between WHOQoL and duration of delirium. There is no significant association between WHOQoL and medical comorbidities. There is no significant association between WHOQoL and substance use. There is no significant association between medical comorbidities and delirium aetiology. There is significant association between delirium severity and duration of delirium. As duration of delirium increases severity of delirium increases. There is no significant association between duration of delirium and delirium aetiology. There is no significant association between delirium severity and medical comorbidities. Conclusions: In this study results showed that there is significant association between delirium is an acute illness with sudden onset with maximum percentage of duration 2-4 weeks, delirium is more in males than females, majority of the care givers are spouses and parents, multiple aetiologies, diminished psychological QoL are associated with increased care giver burden. Family history of delirium is associated with better care giver burden. Employed subjects with delirium have better overall QoL. As duration of delirium increases, delirium severity increases.