bluuebunny/crossref_metadata_2025 huggingface dataset:
CARA KERJA PERAWAT DALAM MEMBERIKAN ASUHAN KEPERAWATAN DAN MENJAGA KESELAMATAN PASIEN SELAMA DI RS
Authors: Yulinartarihoran
Published: December 2019

pelayanan kesehatan dasarnya adalah pemberian keselamatan ke pasien sesuai dengan baik Namun diakui dengan semakin berkembangnya ilmu dan teknologi pelayanan kesehatan khususnya di rumah sakit menjadi kompleks dan berpotensi terjadinya Kejadian Tidak Diharapkan. apabila tidak dilakukan dengan hati-hat dan waspada..Keselamatan adalah suatu keadaan sesorang atau lebih terhindar dari ancaman bahaya\kecelakaan. Kecelakaan merupakan kejadian yang tidak dapat diduga dan tidak diharapkan yang dapat menimbulkan kerugian, sedangkan keamanan adalah aman dan tentarammaka di rumah sakit terdapat ada nya kesalahan obat, dan prosedur, banyak alat medis yang dianggap tidak terlalu penting. Oleh karana itu perawat juga sangat membantu untuk keselamatan pasien dan keluarga . dimana Pelayanan perawat merupakan pelayanan yang sangat banyak waktu nya bersama pasien yaitu 24 jam. di berbagai unit rs Dalam memberikan asuhan keperawatan kepada pasien dan keluarga, perawat melakukan prosedur / tindakan keperawatan yang telah diterapkan oleh rs.
" FAKTOR DETERMINAN YANG MEMPENGARUHI BUDAYA KESELAMATAN PASIEN DIRUMAH SAKIT "
Authors: Lubis Diska Anjali
Published: December 2019

Budaya keselamatan adalah merupakan kunci untuk mencapai tingkat keselamatan dan keselamatan kerja dalam organisasi. Membangun upaya keselamatan ada langkah pertama untuk mencapai sikap baik individu ataupun organisasi ,dan kerja tim. Penelitian ini menggunakan rancangan survey analitik dengan pendekatan cross sectional,
Policy and market drivers for advancing clean energy
Authors: Dahlke Steven , Sterling John , Meehan Colin
Published: December 2019

This chapter reviews important policies and market trends shaping the global development of clean energy technologies. Stimulus policies in the form of feed-in tariffs, tax relief, and renewable portfolio standards along with substantial research & development enabled clean energy projects to overcome early commercialization barriers. As a result, clean energy project costs are now competitive with or lower than conventional fossil fuels in most markets around the world. Policymakers and energy consumers are responding by increasing clean energy targets to high levels approaching 100% in a growing number of jurisdictions. Business models are adapting to this new environment and energy market structures are evolving to enable successful operations of high renewable energy systems. Markets structures, policies, and technologies that enhance system flexibility for efficient renewable energy integration represent the most promising future area of research in this field.
Meningkatkan Akreditasi Rumah Sakit untuk Keselamatan Pasien
Authors: Marina Monika Naulia
Published: December 2019

Abstrak Latar belakang : Akreditasi rumah sakit adalah pengakuan terhadap rumah sakit yang diberikan oleh lembaga independen penyelenggara akreditasi yang ditetapkan oleh Menteri Kesehatan, setelah dinilai bahwa Rumah Sakit itu memenuhi Standar Pelayanan Rumah Sakit yang berlaku untuk meningkatkan mutu pelayanan rumah sakit secara berkesinambungan.Tujuan :untuk meningkatkan akreditasi rumah sakit untuk keselamatan pasien. Metode :metode yang digunakan adalah literature review. Hasil: Di Indonesia ketentuan akreditasi rumah sakit baik tingkat nasional maupun internasional sudah diatur oleh pemerintah melalui Undang-Undang maupun peraturan tertulis. Pembahasan : Saat ini masyarakat semakin sadar untuk memilih layanan kesehatan yang baik. Singkatnya masyarakat mau yang terbaik untuk diri mereka sesuai kondisi mereka saat ini.Penutup: Dalam melakukan tindakan, perawat akan menghadapi berbagai situasi.
RELIVANSI KITAB AYUB DALAM KATEKESE BAGI ORANG YANG MENDERITA
Authors: Junneli
Published: December 2019

AbstrakPenderitaan berasal dari kata dasar “derita”dalam bahasa sensakarta”dhra”yang berarti menahan atau menangung. Derita artinya menanggung atau menahan sesuatu yang tidak menyenangkan. Penderitaan merupakan realitas pada kehidupan manusia. Setiap orang pasti mengalami penderitaan, meskipun untuk setiap orang berbeda tingkatan dari intensitasnya. Penderitaan yang dialami manusia ada yang sangat berat, ada yang ringan, dan ada yang sedang-sedang saja. Berat dan ringan suatu penderitaan bergantung pada sikap batin otang yang bersangkuran. Suatu peristiwa dirasakan sudah sangat membebani, namun peristiwa yang sama bagi yang lain tidak dialami sebagai penderitaan. Ada bermacam-macam penderitaan manusia: pertama, penderitaan lahir, seperti misalnya, kurang makan, tidak punya tempat tinggal, kedua, penderitaan batin misalnya ditolak tidak dianggap, diacuhkan, Kata kunci: relevansi, ketekese, penderitaan
Strategy International UAS FIX
Authors: Grace Karania Melody
Published: December 2019

This study aims to investigate how the multinational corporations form alliance strategies with local businesses under the dynamic institutional environment in the Indonesian context. and to understand how the cross-cultural collaboration between developed market and emerging economies promotes an inclusive global value chain (GVC) through innovation and technology transfer.
Supervisi Pendidikan.
Authors: mutiaracantika@gmail.com
Published: December 2019

this article describe about supervision of education.
Administrasi Sarana dan Prasarana Sekolah
Authors: Ihsan Isnindya
Published: December 2019

Sarana dan prasarana sekolah merupakan salah satu faktor penunjang dalam pencapaian keberhasilan proses belajar mengajar disekolah.
PROMOSI KESEHATAN UNTUK KESELAMATAN PASIEN LANSIA
Authors: Hanhara Rivandi
Published: December 2019

Latar belakang : Keselamatan pasien adalah hak bagi setiap pasien dalam menerima pelayanan kesehatan dan menjadi standar pertama dari tujuh standar keselamatan pasien di rumah sakit. Tujuan : meningkatkan penggunaan program sasaran keselamatan oleh perawat terhadap pasien yang dirawat. Metode : analisis, eksplorasi dan kajian bebas. Hasil dan pembahasan : Sasaran Keselamatan Pasien (SKP) menjadi indikator standar dasar yang utama dalam penilaian Akreditasi Rumah Sakit versi 2012 (KARS, 2013). Perawat merupakan tenaga kesehatan yang sering melakukan kontak atau hubungan langsung dengan pasien. Perawat memiliki peranan dan tugas penting dalam pelayanan kesehatan. Kesimpulan : Ada enam sasaran keselamatan pasien yaitu Ketepatan identifikasi pasien; Peningkatan komunikasi yang efektif; Peningkatan keamanan obat yang perlu diwaspadai; Kepastian tepat- lokasi, tepat-prosedur, tepat-pasien operasi; Pengurangan risiko infeksi terkait pelayanan kesehatan; dan Pengurangan risiko pasien jatuh.
PENDIDIKAN GLOBAL Oleh Kelomok 6, nama Riyadoh batubara, Riska Rangkuti, Khusnul Khofifah dan Nur Atita
Authors: ritonga indah pertiwi
Published: December 2019

Kemajuan teknologi, perdagangan antar negara, pertukaran budaya,kepedulian terhadap lingkungan, persaingan pasar, kelangkaan dalam sumber daya alam dan semakinketatnya perlombaan senjata antarnegara adi kuasa marupakan gambaran dari kondisi masyarakat internasional yang semakin kompleks. Adanya ketergantungan antar bangsa dan negara menimbulkan bentuk-bentuk kerjasama di segalan bidang yang sekaligus menimbulkan persaingan dan konflik.Kehidupan dalamera globalisasi telah terbawa pada suatu arus yang mengharuskan kita mengubah cara pandang terhadap diri sendiri maupun orang lain.Pandangan suatu bangsa atau negara yang berpaling dari pandangan global hanya akan membuat negara atau bangsa itu terisolir. Dalam era globalisasi tak ada satu bangsa atau negara pun di dunia ini yang dapat bersembunyi dari pengaruh era globalisasi.Dengan demikian, adanya saling keterkaitan atau ketergantungan hidup di bumi ini telah menimbulkan peningkatan pentingnya penguasaan ilmu pengetahuan dan keterampilan profesional dari warga dunia yang menjadi dimensi global baik dari fenomena politik, ekonomi maupun budaya.
HUBUNGAN KOLABORASI ANTARA PERAWAT DENGAN APOTEKER DALAM MENINGKATKAN KESELAMATAN PASIEN
Authors: Marpaung Sri Harvita Sari
Published: December 2019

Latar belakang : Dalam meningkatkan keselamatan pasien perawat berkolaborasi dengan tim medis lainnya salah satunya dengan orang farmasi. Hubungan perawat dengan apoteker merupakan hal yang sangat intim dalam penerapan keselamatan pasien dalam hal pemberian obat kepada pasien. Tujuan : untuk mengetahui hubungan kolaborasi antara perawat dengan apoteker dalam meningkatkan keselamatan pasien di rumah sakit. Metode : literature review dengan pendekatan jurnal atau artikel, buku dan e-book yang relevan dan akurat serta berfokus pada Menjaga Keselamatan Pasien dengan Interprofesional Collaboration. Adapun jurnal atau artikel dan e-book yang digunakan pada literature review adalah jurnal atau artikel dan e-book yang didapatkan dengan menggunakan Google Scholar, Portal Garuda, dan Jurnal Keperawatan Indonesia. Hasil : dapat memberikan informasi mengenai hubungan kolaborasi perawat dengan apoteker dengan peningkatan keselamatan pasien. Pembahasan : hubungan kolaborasi perawat dengan apoteker dalam meningkatkan keselamatan pasien di rumah sakit. Kesimpulan : Keselamatan pasien dapat ditingkatkan melalui beberapa hal salah satunya adalah pengawasan dalam pemberian obat, bagaimana pada dasarnya dalam masa perawatan pasien dalam mengatasi masalah yang dialami oleh pasien obat merupakan hal yang sangat intim dengan pasien. Oleh karena itu, hubungan kolaborasi antara perawat dengan apoteker sangatlah penting dalam perawatan pasien.
PELAKSANAAN KESELAMATAN DAN KESEHATAN KERJA TERHADAP PASIEN DI RUMAH SAKIT
Authors: Sitepu Ike Emanita br
Published: December 2019

Dalam sebuah rumah sakit tentu saja ada petugas kesehatan begitu pun juga tentu saja ada pasien. Dalam merawat pasien sangat ditekankan agar menjaga keselamatan pasien tersebut. Agar tidak muncul penyakit lain diluar penyakit yang dibawa pasien untuk disembuhkan, maka dibutuhkanlah untuk melaksanakan keselamatan dan kesehatan pasien. Terlepas dari itu, petugas kesehatan juga dibutuhkan keselamatan serta kesehatan kerja dalam merawat pasien di rumah sakit. Hal tersebut untuk menghindari kecelakaan kersa saat sedang melakukan tindakan ataupun sedang merawat pasien. Baik di ruang rawat inap, maupun di UGD. Karena bisa saja akibat kelalaian dalam melakukan tidakan, petugas kesehatan jadi celaka. Baik sengaja maupun tidak sengaja. Oleh sebab itu disarankan agar menerapkan pelaksanaan keselamatan dan kesehatan kerja terhadap pasien di rumah sakit.
UAS Strategi Internasional
Authors: darmawan natanael
Published: December 2019

strategi internasional
"IMPLEMENTASI SASARAN KESELAMATAN PASIEN DI RUMAH SAKIT"
Authors: Hutasoit Enjelina SP
Published: December 2019

Isu keselamatan pasien menciptakan pandangan baru mengenai mutu pelayanan. Mutu pelayanan yang baik masih belum cukup berarti bagi pasien tanpa memperhatikan derajar risiko dan keselamatan pasien. Tinggi rendahnya mutu pelayanan sejalan dengan fasilitas pelayanan untuk mencapai keseimbangan terbaik antara derajat risiko dan manfaat keselamatan yang diterima oleh pasien. PERMENKES RI Nomor 11 Tahun 2017 tentang keselamatan pasien sebagai standar terbaru yang didalamnya meliputi I adalah ketepatan identitas pasien, II adalah peningkatan komunikasi efektif, III adalah peningkatan keamanan obat yang perlu diwaspadai, IV adalah kepastian tepat lokasi, prosedur, dan pasien operasi, V adalah pengurangan risiko infeksi terkait pelayanan kesehatan, VI adalah pengurangan risiko pasien jatuh.
Global Value Chain and International Strategic Alliance
Authors: Grisselda Almas
Published: December 2019

Kolaborasi lintas budaya antara pasar negara maju berkembang mempromosikan Global Value Chain (GVC) inklusif melalui inovasi dan transfer teknologi. Khususnya pada industri rotan global, terdapat tiga tipe kolaborasi lintas budaya di GVC. Perusahaan multinasional membentuk strategi aliansi internasional untuk kelangsungan jangka panjang bisnis. Partnership antara perusahaan lokal dengan multinasional bisa dilakukan dengan beberapa alternatif strategi untuk meningkatkan kinerja perusahaan melalui peningkatan kreativitas dan inovasi.
STATISTIK ILMU SOSIAL
Authors: Gerardus Uda , Atti Astri , Kleden Maria Agustina
Published: December 2019

Buku tentang Statistik pada ilmu-ilmu sosial
Longitudinal changes and historic differences in narcissism from adolescence to older adulthood
Authors: Chopik William J.
Published: December 2019

In the debate about whether or not narcissism has been increasing in recent history, there is a lack of basic information about how narcissism changes across the adult lifespan. Existing research relies on cross-sectional samples, purposely restricts samples to include only college students, or follows one group of individuals over a short period of time. In the current study, we addressed many of these limitations by examining how narcissism changed longitudinally in a sample of 747 participants (72.3% female) from age 13 to age 77 across six samples of participants born between 1923 and 1969. Narcissism was moderately stable across the lifespan (rs ranged from .37 to .52), to a comparable degree as other psychological characteristics. We found that more maladaptive forms of narcissism (e.g., hypersensitivity, willfulness) declined across life and individual autonomy increased across life. More later-born birth-cohorts were lower in hypersensitivity and higher in autonomy compared to earlier-born birth-cohorts; these differences were most apparent among those born after the 1930s. The results are discussed in the context of the mechanisms that drive both changes in narcissism across the lifespan and substantive differences in narcissism between historical periods.
The legal and scientific challenge of black box expertise
Authors: Searston Rachel A , Chin Jason
Published: December 2019

Legal commentators widely agree that forensic examiners should articulate the reasons for their opinions. However, findings from cognitive science strongly suggest that people have little insight into the information they rely on to make decisions. And as individuals gain expertise, they rely more on cognitive shortcuts that are not directly accessible through introspection. That is to say, the expert’s mind is a black box — both to the expert and to the trier of fact. This article focuses on black box expertise in the context of forensic examiners who interpret visual pattern evidence (eg fingerprints). The authors review black box expertise through the lens of cognitive scientific research. They then suggest that the black box nature of this expertise strains common law admissibility rules and trial safeguards.
Mortality in Emergency Services in a University Teaching Hospital: A Retrospective Study
Authors: Shrestha Tirtha Man , Aacharya Ramesh P , Neupane Ram P , Prajapati Bigyan
Published: December 2019

Introduction: Emergency services are the gateway between the community and hospital that provides 24-hour access for most needy patients in critical and emergency conditions. Mortality rate varies in emergency department across the world and even in different emergency units of the same hospital. This retrospective study was done in adult emergency services of a tertiary hospital to determine mortality rate and analyze causes of death.

Methods: A retrospective observational study of mortality cases to analyze mortality rate and causes of death of patients for a period of 6 months between October 2017 to March 2018 was carried out in the adult emergency services of Tribhuvan University Teaching Hospital, Kathmandu. Data required were collected from copies of death certificates.

Results: During the study period, a total of 128 patients died in emergency, accounting 0.5% of total patient. Male deaths (52.3%) were slightly higher compared to female deaths (47.7%). Age group 66-75 years had the highest (24.2%) of total mortalities in the emergency. The most common immediate cause of death was sepsis/septic shock (21.9%) followed by cardiopulmonary arrest, aspiration, respiratory failure, other causes of shock and poisoning. The commonest antecedent cause of death was attributed to respiratory causes. Similarly, the most common contributory cause of death was chronic obstructive pulmonary disease.

Conclusion: Older age group is prone to the mortality risk. Sepsis/septic shock was the most common immediate cause of death. Pneumonia was the most common antecedent causes of death. Chronic obstructive pulmonary disease was the commonest contributory cause.
Outcome Analysis of Lipomeningomyelocele Repair in Children in a Tertiary Care Center in Nepal
Authors: Koirala Puspa R , Pradhanang Amit B , Sedain Gopal , Sharma Mohan R
Published: December 2019

Introduction: Lipomeningomyelocele (LMM) is a common neural tube defect especially prevalent in low income countries. When they get appropriate care, long term result is generally good provided the patient receives good neurosurgical, pediatric and rehabilitation care. Surgery is the mainstay of treatment. Our aim was to analyze immediate and long-term results of lipomeningomyelocele repair in symptomatic patients presenting to TU Teaching Hospital, Kathmandu, Nepal.

Methods: Thirteen patients admitted to Department of Neurosurgery from January 2017 to December 2018 were evaluated. All patients underwent MRI of whole spine before surgery. Surgical procedures involved total excision of lipoma and repair in 10 patients and subtotal excision and repair in 3 patients. Division of filum terminable could be donein 8 patients. Follow up varied from 6 months to 2 years.

Results: This study included 8 (61.5 %) patients of lumbosacral LMM, 3 (23%) patients of sacral LMM and 2 (15.38%) patients of thoracolumbar LMM. About 2 (15.38%) were operated before 3 months of age, 2 (15.38%) were operated between 3-6 months of age, 5 (38.46%) were operated between 6-12 months of age and 4 (30.7%) were operated after 1 year. All children except one presented with lump on back since birth and four presented with urinary incontinence, one presented with bilateral club foot. Four (30.7%) patients had weakness of one or both lower limbs. Two (15.38%) patients had improvement in urinary incontinence, two unchanged and one had developed urinary incontinence postoperatively. Four children with had weakness of lower limbs; one patient improved whereas three patients did not improve postoperatively. There was no development of post operative hydrocephalus after LMM repair. Three (23%) patients developed wound infection who responded well with regular dressings and antibiotics.

Conclusion: Lipomeningomyelocele repair can be done with satisfactory outcome with total excision of lipoma and division of filum terminale. Patients with residual diploma and undivided filum terminale should be observed closely for the development of progressive neurological deterioration.
Ventilator-Associated Pneumonia in Neurosurgical Patients: A Tertiary Care Center Study
Authors: Shrestha Dipendra K , Rajbhandari Binod , Pradhanang Amit , Sedain Gopal , Shilpakar Sushil K , Pradhan Saurav
Published: December 2019

Introduction: Ventilator-associated pneumonia (VAP) is a well recognized complication in patients who are admitted to the Intensive Care Unit (ICU). A number of factors have been suspected or identified to increase the risk of VAP in Neurosurgical patients. Early and rapid diagnosis and initiation of the appropriate antibiotic treatment reduce mortality and decrease the development of MDR organisms. The aim of our study is to determine the incidence of VAP in the neurosurgical patients and also to assess the probable contributing neurosurgical risk factors and find out the causative bacterial pathogens and the resistant pattern of these bacteria in neurosurgical patient in ICU of our institute

Methods: A retrospective observational study of 106 neurosurgical patients who were on mechanical ventilation for more than 48 hours was done.

Results: Out of 106 patients, 35 patients fulfilled the clinical and microbiological criteria for the diagnosis of VAP. The commonest age group involved was between 15-25 years of age with male preponderance. Head injury was the commonest etiology. There was a linear correlation between the number of days in ICU and the development of VAP. The majority of the pathogen isolated were gram-negative bacteria and all were sensitive to Colistin.

Conclusion: Head injury is a significant risk factor for VAP. Prolonged mechanical ventilation is an important risk factor for VAP.
Comparison of Sevoflurane and Isoflurane for Myocardial Protection During Coronary Artery Bypass Surgery in a Tertiary Care Center in Nepal
Authors: Bastola Priska , Pradhan Bishwas , Basnet Madindra
Published: December 2019

Introduction: Myocardial protection during Coronary Artery Bypass Graft (CABG) has always been an area of concern so we aimed to evaluate the level of release of Creatine Phosphokinase (CPK-MB) and Troponin I (cTnI) at various time intervals in the first 24 hours after on pump CABG in patients receiving either Sevoflurane or Isoflurane. Furthermore clinically relevant patient outcomes were also evaluated in patients undergoing on pump coronaryartery bypass grafting.

Methods: This was a prospective randomized trial in patients undergoing on pump coronary artery bypass graft surgery, which was conducted from January 2016 till June 2017. A total of 105 patients were enrolled out of which there were 53 in Isoflurane and 52 in Sevoflurane group who received the respective volatile anesthetic agents throughout the surgery except during bypass at 1-1.5 MAC. The primary outcome was comparison of the CPK MB and cTnI levels at 0 hr, 6 hr, 12 hr and 24 hr after surgery from baseline, whereas the secondary outcomes were duration of intensive care unit stay, usage of vasopressors and inotropes, renal dysfunction, stroke.

Results: No significant difference in CPK MB and cTnI levels at all time intervals in both the groups, the other secondary outcome parameters were comparable.

Conclusion: The study found no difference in the cardiac markers between the two anesthetics. Based on the data, Sevofluraneand Isoflurane might be used equivalently in patients undergoing coronary artery bypass graft surgery with extracorporeal circulation without any difference in their myocardial protection function.
Anorectal Autoeroticism: A Case Report
Authors: Tulachan Pratikchya , Shrestha Kenison , Chapagai Manisha , Dhungana Saraswati , Pant Sagun B , Lama Pratik , Bhandari Ramesh S
Published: December 2019

Anorectal autoeroticism is one kind of paraphilia where individual attains sexual pleasure through self inserting objects into ones rectum. We present here a case of 40 years old man presented in Surgery department with retention of steel glass into his rectum which he had inserted himself to achieve sexual satisfaction.
The Result of Elections to the Śląskie Voivodeship Assembly in 2018 in Reality of the Territorial Heteronomy
Authors: Myśliwiec Małgorzata
Published: December 2019

The main aim of the paper is the theoretical analysis of the concept of the territorial heteronomy. Conclusions concerning the idea of territorial autonomy, regionalism or federalism easily can be found in the scientific literature. But they are useless to investigate and explain many political processes and political preferences in states of the Central and Eastern Europe. It is because states of this part of the continent did not have a chance to create and develop their own models of classic administration institutions in the nineteenth century, inter alia the local and regional government. Their only experience in this area is limited to the interwar period between 1918 and 1939.  They have gained a new chance for a democratic division of public tasks after the collapse of the communist system in the very end of the twentieth  century. But in that period they have focused more on the horizontal division of powers than on the vertical one. For that reason up till today political phenomena in the political centre have more importance than the regional policy impact attempts. The inspiration for such a research were electoral results obtained by two regional parties at elections to the Śląskie Voivodeship Assembly in 2018.
The Influence of Corruption Scandals on Government Accountability
Authors: Żerkowska-Balas Marta , Sroka Anna
Published: December 2019

The objective of the article is to examine whether corruption scandals involving members of the ruling party lead to changes in support for the government. It will also explore the extent to which the eruption of such scandals and reporting on them leads to an increase in the number of those opposed to the government, and whether in the long run this leads to the activation of the carrot-and-stick mechanism in respect of the governing political party, reflected in increased voting instability during subsequent elections.
Candidate processes for autism spectrum disorders revealed by copy number variation analysis
Authors: Zelenova M. A. , Vorsanova S. G. , Iourov I. Y.
Published: December 2019

Despite the large number of candidate genes for mental disorders, molecular mechanisms of the majority remain unknown. To fill this gap, we have studied genomic networks-candidates (instead of genes) in a group of children with brain disorders. The identification of such processes seems to be more promising for developing therapeutic strategies in contrast to candidate gene identification.
New approaches to pharmacogenetics of drug-induced hyperprolactinemia in patients with schizophrenia
Authors: Ivanova S. A.
Published: December 2019

The pathogenesis of the development of drug-induced disorders while taking antipsychotic drugs is not well understood. The aim of the work is to study polymorphic variants of the multidrug resistance protein gene and genes encoding the metabolism and synthesis of dopamine and serotonin enzymes in antipsychotic-induced hyperprolactinemia in schizophrenia patients. As a result of a comprehensive study of 446 patients with schizophrenia and genotyping of 25 polymorphic variants of the MDR1, COMT, MAO-A, MAO-B, TPH1 and TPH2 genes, associations of polymorphisms rs1045642, rs2032582, rs4148739 (MDR1), rs6323 (MAO-А), rs1799836 (MAO-B) were revealed with the development of hyperprolactinemia. Further research is needed to develop personalized approaches to therapy.
The opportunity of application of neurophysiological tests — schizophrenia endophenotypes for studying the role of genetic factors in cognitive processes in healthy subjects and in psychiatric diseases
Authors: Kirenskaya A. V. , Storozheva Z. I. , Kibitov F. O.
Published: December 2019

The study of effects of genetic polymorphisms implicated in dopamine (COMT, DRD2) and GABA (GAD1) activities in the prefrontal cortex on antisaccades (AS) and evoked potential P300 measures was conducted with participation of 55 healthy subjects and 72 schizophrenic patients. The significant interaction of genotype and disease was found for most of the studied AS and P300 measures. The worse task performance and decreased efficacy of cortical activation were revealed for the associated with schizophrenia risk polymorphisms.
Genetic risks of addictive disorders in adolescents: phenotypic effects
Authors: Yakovlev A. N. , Pashkevich N. V. , Vitchinkina V. I.
Published: December 2019

In several unrelated small samples examined correlation between genetic risk of chemical dependence, calculated on the basis of the contribution of geomarkers dopamine system, and phenotype of adolescents 14-17 years of age, not suffering from addiction. When genetic risk increases, the tendency to behavioural disorders increases, the tendency to abandon positive forms of self-assertion increases, the intensity of euphoria increases at the first drug samples, and the ability to predict the consequences of drug use decreases. The obtained correlations may be important for understanding the mechanism of dependence formation in adolescents with high genetic risk and development of individual prevention programs. However, these observations need to be confirmed in more representative studies.
Dopamine transporter knockout rats as the new preclinical model of hyper- and hypo-dopaminergic disorders
Authors: Sukhanov I. , Leo D. , Tur M. A. , Belozertseva I. V. , Savchenko A. , Gainetdinov  R. R.
Published: December 2019

Rat line lacking the dopamine transporter (DAT-KO rats) was recently developed. Lack of DAT in these mutants manifests behaviorally as spontaneous hyperactivity and cognitive deficits. It has been shown that d-amphetamine and methylphenidate paradoxically calm down these animals. Also, the inhibition of dopamine synthesis in DAT-KO rats represents a straightforward approach for developing the model of severe dopamine deficiency exhibiting characteristic akinetic phenotype which can be reversed by treatment with L-DOPA that used in Parkinson’s disease. These results support the usefulness of DAT-KO rats as models of the disorders associated with dopaminergic dysfunction.
The Canadian Liver Foundation celebrates 50 years of commitment to hepatology
Authors: Roberts Eve A , Fisher MM
Published: December 2019

Founded in 1969, the Canadian Liver Foundation (CLF) was the first foundation worldwide to support research and education relating specifically to the liver and liver diseases. This year marks its 50th anniversary. It has been highly effective in promoting hepatology in Canada.
Effect of Cr and Ni on the microstructural evolution in Co–Re–Cr–Ni alloys
Authors: Esleben Katharina , Gorr Bronislava , Christ Hans-Jürgen , Pritzel Christian , Mukherji Debashis , Rösler Joachim , Beran Přemysl , Strunz Pavel , Hoelzel Markus , Gilles Ralph
Published: December 2019

The present study focuses on the microstructural evolution in Co–Re–Cr–Ni alloys at high temperatures. Four alloys with different Cr and Ni contents were studied. The microstructural examinations were performed using complementary methods of scanning electron microscopy, transmission electron microscopy, differential scanning calorimetry and neutron diffraction. Based on the experimental results and assisted by thermodynamic calculations, the effect of Cr and Ni on the microstructure could be identified. While both Ni and Cr, but Cr only if Ni is also present in the alloy, stabilize the fcc phase, the impacts of these elements on the σ phase formation are different. It was found that the temperature stability of the σ phase enhances with increasing Cr content, whereas Ni reduces the required Cr concentration for the σ phase formation. The evaluation of the Cr and Ni effects on the microstructural evolution contributes to a fundamental understanding of the alloy behaviour and, thus, is a key aspect for successful alloy development.
The Power of Deficit Discourses in Student Talk about Writing
Authors: Makmillen Shurli , Norman Kim
Published: December 2019

Does engagement with writing centre consultants in one-on-one consultations help students shift from remedial discourses toward meta-cognitive awareness more in keeping with the nature of peer review in an academic setting? This study investigates this question through looking longitudinally over a four-year period in a Canadian university writing centre. We situate this research within wider discussions of Standard English and remediation in student academic writing, as well as writing centre research that explores correlations between numbers of writing centre visits and both students’ confidence as writers and their intrinsic motivation. Using a corpus-supported genre and discourse analysis, we focus on student appointment requests, as well as summative writing centre consultant notes. Results suggest that deficit discourses are highly tenacious, which we explain in part as the result of the constraints inherent in the genre of requests for help, and also in terms of the institutional positioning of writing centres.
Current challenges of underground water resources research in volcanic areas of the Armenian highlands (case study: mount Aragats)
Authors: Vardanyan V. P.
Published: December 2019

From the hydro-geological perspective the territory of the Central Volcanic Highlands of Armenia is a highly elevated area which mainly belongs to the hydrodynamic zone of intense underground flow.

Our systematic and planned research aimed at studying groundwater in the Central Volcanic Highlands of Armenia covers the following regions: Mount Aragats, Gegham, Vardenis and Syunik Volcanic Highlands, the Ararat, Shirak and Sevan valleys, the Lori Volcanic Plateau etc.

In the Armenian Highlands, along the periphery of Mount Aragats, the purpose of the conducted studies was to determine the possibilities of applying the vertical electrical sounding (VES) method for mapping the basement relief of water-resistant rocks and identifying the aquifers.

In general, the lava of Armenian volcanic highlands is characterized by the formation and accumulation of two main types of underground runoff: concentrated and distributed. Concentrated runoff is a concentrated underground stream formed in the buried valleys and moves in a certain direction along a paleo-relief. Distributed runoff is a relatively dispersed underground stream formed in the buried watershed between paleo-valleys and moving in their direction. It feeds the concentrated runoff.

Based on the hydro-geophysical studies, the main conclusions on distribution and exploitation of groundwater across certain volcanic regions of the Central Volcanic Highlands of Armenia are presented. Mount Aragats, where electrical exploration surveys took place using the VES method, is presented as a case study. Hydro-geophysical studies made it possible to analyze certain drainage basins of the rock massif in order to allow a more detailed “dissection” of the groundwater runoff.

As a result, a summary map of the paleo-relief was compiled. The map shows the distribution of the underground runoff of the volcanic massif of Mount Aragats which forms an important basis for conducting hydrogeological initiatives aimed at solving the problem of fresh water shortage at the national level.
EFEITO DO USO DE FTE BR12 NA PRODUTIVIDADE INICIAL DO CAPIM MASSAI
Authors: Cunha Marcelo Könsgen , Viana Suzelma Silva , Sousa Mike Kovacs de
Published: December 2019

A bovinocultura de corte é uma atividade importante para o Brasil e o principal alimento dos bovinos é a forragem oriunda das pastagens. Contudo, de modo geral, as pastagens não são estabelecidas e manejadas adequadamente, o que impacta negativamente na produtividade e viabilidade da atividade. A adubação com micronutrientes, para o estabelecimento de pastagens, é pouco estudada e, nos poucos estudos, há poucas evidências de benefícios, quando as recomendações publicadas são empregadas. As fritas ou FTE (Fritted Trace Elements), apesar de sua baixa solubilidade, ainda são as mais indicadas e citadas em textos técnico-científicos para fornecer micronutrientes para plantas forrageiras. Diante disto, o presente trabalho objetivou verificar o efeito da adubação de micronutrientes, usando FTE BR12, na produtividade inicial do capim Massai. Para desenvolver o trabalho, foi montado um experimento com cinco tratamentos e cinco repetições, em um delineamento completamente casualizado. Os tratamentos consistiram de diferentes doses de FTE BR12: zero, 28, 56, 84 e 112 kg.ha-1. Foram realizados dois cortes de forragem e o resultado mostrou que os tratamentos não influenciaram a produtividade de matéria seca. Conclui-se que o uso de FTE BR12 não influenciou a produtividade inicial do capim Massai.
Les troubles périnéosphinctériens chez les patients souffrant de troubles du comportement alimentaire
Authors: Pourtal C. , Volondat L. , Lambert S. , Robert J. , Rousselet M. , Grall-Bronnec M.
Published: December 2019

Contexte : Les troubles périnéosphinctériens (TPS) survenant chez les patients souffrant de trouble du comportement alimentaire (TCA) sont des complications sous-abord ées dans la littérature. Le but de cette revue de la littérature était de faire le point sur l’état des connaissances actuelles pour aider le clinicien prenant en charge les TPS à les mettre en lien avec les TCA, et le clinicien prenant en charge les TCA à les prévenir et à les repérer le plus précocement possible, dans une perspective de réduction des risques et des dommages.

Méthode : Deux revues de littérature ont été conduites, l’une portant sur les TPS d’origine digestive, l’autre sur les TPS d’origine urinaire. La sélection des articles s’est faite en nous référant aux recommandations PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) et à partir des bases de données PubMed et ScienceDirect.

Résultats : Douze articles ont été retenus. Les TPS identifies sont la constipation, l’incontinence fécale, l’incontinence urinaire et le prolapsus rectal. Ils sont secondaires aux effets de la malnutrition sur la composante musculaire ainsi qu’à la pression abdominale exercée par des comportements visant à réguler la prise de poids, tels que les exercices physiques réalisés en hyperpression, les efforts de poussée lors de l’émission des selles et les vomissements provoqués.

Conclusion : Une anamnèse précise et méticuleuse chez les personnes présentant un indice de masse corporel bas semble primordiale. L’usage de laxatifs est à proscrire avant un programme de renutrition d’au moins trois semaines.
Go West
Authors: Guy Shlomit
Published: December 2019

This article discusses the transformations in Israeli football over the last two decades, exploring the top-down and bottom-up motivations present in local football and characterizing foreign practices as more Western, or even more ‘civilized’, as Norbert Elias would describe it. Yet, the transformations of English and European football over the last three decades suggest that ‘Western’ is not so much a geographic term as it is a political, moral, and social status, one requiring English, European, and Israeli football to make dedicated political and cultural investments in numerous arenas.
Each Female Fan Has Her Own Story
Authors: Rapoport Tamar , Noy Efrat
Published: December 2019

This article advocates autoethnography as a critical feminist methodology for using personal testimony to investigate women’s experience and performance of fandom The article’s centerpiece is an analysis of the personal testimonies of three women—researcher-fans of different ages—of a fan-owned club Hapoel Katamon Jerusalem. In addition to revealing women’s gendered-based experiences and the different ways in which women acquire and perform fandom, their personal stories prove valuable for exposing the gendered regime of the football field. Moreover, they reveal how women who are not fluent in the hegemonic language of fandom make their way in the fandom field as they seek their own voice and position in it. The analysis suggests that women’s participation can disrupt the hegemonic masculinity of fandom and challenge its established boundaries, thereby problematizing accepted definitions of the authentic fan.
Optimization of the Production Process of Sealing Bricks in a Ceramic Factory in Urucurituba City in Amazonas – Brazil
Authors: Fernandes Vital Denilson , Barbosa de Alencar David , Cezar Aparício De Souza Mauro , Priscilla Tregue Costa Alexandra , Carlos Tavares Amorim Francisco , Travessa Amorim Ana Jaqueline , Eduardo de Oliveira Carlos
Published: December 2019

In recent years there has been a high growth in Brazil, in the construction industry this event reflects a great economic development in the regions of the country, in the Amazon, the ceramic brick industry has been gradually increasing to meet this demand, especially in the interior of the state. In them there are failures and waste during its manufacturing process that greatly affects the final product. This article aims to employ the quality tools in the production process of a ceramic pottery that is located in the city of Urucurituba - AM, through them to discover the flaws and propose improvements in the production process of sealing bricks so that there is no problems in the final product. Through site visits data were collected through interviews with employees and the plant manager, the visit also allowed the mapping of the process of manufacturing eight-hole bricks, from this verification it was possible to apply the flowchart that allowed describing Throughout the process flow, the Ishikawa Diagram was also applied, which made it possible to detect faults (cracks and cracks) and their root causes. These occur during the brick production process and used the 5W2H, which helped to organize the ideas. and make a proposal to solve the problems, and bring quality to the final product
Expert System Development for the Prevention of Hoof Pathologies Applied to the Intensive Swine Production
Authors: Mollo Neto Mario
Published: December 2019

Claw lameness can be associated with biomechanical factors caused by imbalances of the pressure distribution under the hooves when swine are confined in modern facilities with hard concrete flooring. Comparing hoof pressure distribution data of swine boars walking over two different types of floors (standard concrete vs. 3mm rubber mattress) in previous research, it was found a great advantage favoring the rubber mat flooring showing that it was capable of reducing pressures under the claws as the pressure became more evenly distributed under this treatment resulting in balanced weight-bearing surfaces. The objective of this study was to develop an expert system based on Fuzzy logic algorithm for the prevention of hoof pathologies applied to the intensive swine production by estimating occurrence of claw lesions based on the association of knowledge gathered on pressure distribution from previous research as well as the influences of nutrition, friction coefficients found on different types of available flooring, hoof sizes and animal weight on the welfare of the swine’s locomotory system. The data were correlated initially using Matlab® platform associating expert’s knowledge and literature through a knowledge system that weights the variables according to their impact on claw health. The final user interface was coded using Microsoft Visual Studio Rapid Application Development tool and the resulting system was validated in several different laboratory scenarios and its performance was considered to be satisfactory according to findings in the literature. The expert system was coded and the authors concluded that the system could be a great contribution and advance in the swine’s industry, nonetheless, its performance still requires field testing for fine adjustments which should be encouraged to be carried out in further researches.
Study of the Physical Aspects of Residential Soils of Iranduba - AM
Authors: De Araújo Reis Rômulo , Moraes de Oliveira Bruna , Da Silva Oliveira Lívia , Barbosa de Alencar David
Published: December 2019

The objective of this work is to study the physical indices of soil samples collected in different points of the municipality of Iranduba - Am. The parameters analyzed were moisture content, porosity, aeration degree, specific weight among others. For the physical characterization of the soil, samples with deformed structure were collected, prepared according to procedures described in the standard procedures described by the NBR 6457 standard (ABNT, 1986). The tests were performed using a high precision glass pycnometer. The tests resulted in samples with high voids and porosity, lower values ​​of saturation degree as their low percentage. The specific grain weight presented satisfactory results meeting the criteria established by the standard.
Case Study on Work Safety Conditions in Carauari - Amazonas
Authors: Oliveira de Mesquita Fabrícia Rogéria , Justino do Carmo Pedro Paulo , Ferreira Umbelino Mariana , Dos Santos Santarém Sara , Barbosa de Alencar David , Estanislau Sanches Antônio
Published: December 2019

The construction sector is the largest generator of occupational accidents, as it directly covers the worker. The implementation of preventive actions reduces the risks and provides a healthy environment, giving more security to the worker and daily activities. Based on these data, it is observed that the city of Carauari, in the interior of the Amazon, is still adapting the conditions of work safety, regarding the use of PPE and training that should be offered to work at height, which factors minimize accidents at the construction site.
Application of AHP Method to Aid Destination Choice of Pre-Production Models in a Textile Industry
Authors: Ramos Karine , Menegon Bristot Vilson , Batista Gesuíno David , Carlos Just Márcio , Brogni Uggioni Bruno , Menegon Bristot Vilmar , Oliveira Cardoso Richard , Kalfeld Edimar , Pedro Guimarães Filho Leopoldo
Published: December 2019

The study analyzed, through the Analytic Hierarchy Process (AHP) technique, the decision-making tool, the best resolution for the final disposal problem of pre-pruduction models of a garment company. Obtaining data was based on the identification of the problem, general understanding of how to improve and finally the application of the AHP method, it was concluded that the best decision was archiving the pieces, guaranteeing fidelity in the reproduction of the product and the aid for the development of new parts.
Non-Conformity Reduction in Painting Sector in Plastic Parts in a Company of the Industrial Pole of Manaus - IPM
Authors: Matos Damasceno Leonardo , Barbosa de Alencar David , Tregue Costa Alexandra Priscilla , Estanislau Sanches Antônio
Published: December 2019

Among the focuses of industries is the reduction of waste costs, this makes the product competitive, reduces the number of failures and, consequently, the price to the end consumer. Industrial Pole of Manaus (I.P.M.) promotes the economic development of the region and brings together large and medium-sized companies that use plastic painting as one of the stages of their production process and care about quality and invest in management methodologies, resources and technologies to optimize your processes. With this in mind, improvements were proposed in a company to reduce defects in paint in plastic parts in the motorcycle sector, and the use of appropriate quality tools and management techniques, which enabled a more assertive decision-making, measured its effects and solved the causes of the problem. The type of non-conformity of the highest level of occurrence was approached, which are defects classified as impurities, from it were identified root causes found, all variations in processes that benefit the emergence of this defect and opportunities for improvements in the process. This it can be done only with behavioral changes and with minimal economic investment.
A PROJECT PROPOSAL FOR A TRUFFLE MICRO-ENTERPRISE
Authors: Bindá Gondim Letícia , Barbosa de Alencar David , Tregue Costa Alexandra Priscilla , Estanislau Sanches Antônio
Published: December 2019

The present work uses knowledge obtained in the course of Production Engineering, with the purpose of presenting a proposal of factory project of a handicraft truffle microenterprise. The study proceeds in the factory design area, as well as in the general administrative area, especially entrepreneurship. For this, market information, layout proposal, raw material used material costs, a good location, basic equipment were presented, in order to bring knowledge that helps to visualize what you need for the opening of a small homemade factory, of truffle production. All data were collected through bibliographic research, and through academic knowledge acquired during the course of Production Engineering. The study aims to collect information that help the entrepreneur to start his own business, efficiently and effectively, in view of quality and productivity, so that you can obtain a satisfactory financial return.