bluuebunny/crossref_metadata_2025 huggingface dataset:
The Bible, Historical Jesus, and Diversity
Authors: Olajide Michael Deji
Published: September 2023

This book chapter explores relevant data on diversity in the Bible and the life, ministry, and teachings of the historical Jesus. It is evident that the Bible, both in its contexts and contents, is replete with diversity. Starting from the creation narrative, the social and ethnic make-up of the biblical world is marked by diversity. The creation narrative in Genesis 1-2, the progenitor is simply called “adam,” which means “humankind.” Adam and Eve were not Europeans, Jews, or Africans. Their tribal default and ethnic identity are unknown, they were simply the progenitors of all peoples and tribes. Israel was ethnically diverse, which mirrors the ethnic configuration of the biblical world. Likewise, the historical Jesus ministered to both the Jewish people and the Gentiles. In his teachings and parables, Jesus made reference to non-Jewish individuals in commendable ways. Paul followed this similar path by emphasising active unity in the church, the type of unity that joins together diverse ethnic groups because of their common identity and position in Jesus Christ.
Deep Learning Fusion for Multimedia Malware Classification
Authors: Maleh Yassine
Published: September 2023

In the face of escalating cyber threats posed by malware, advanced detection techniques are crucial. This study introduces a cutting-edge approach that merges convolutional neural networks (CNNs) and long short-term memory recurrent neural networks (LSTMs) for enhanced malware classification. The effectiveness of this method is rigorously examined using Microsoft's BIG Cup 2015 dataset. By combining CNN's ability to capture local features and LSTM's proficiency in processing sequence data, our approach achieves remarkable accuracy (98.73%) in identifying malicious behaviors. This research contributes an extensive exploration of deep learning models, an innovative CNN-LSTM hybrid architecture, and a comprehensive case study showcasing its superior performance. The presented approach signifies a significant stride in bolstering cybersecurity against the ever-evolving threat of malware.
Securing Fog Computing Through Consortium Blockchain Integration
Authors: Almaiah Mohammed Amin , Alkdour Tayseer
Published: September 2023

The authors have developed an innovative topology by amalgamating consortium blockchain, often referred to as supervisory blockchain, with fog computing. The proposed system is organized into three distinct layers: the application layer, the fog layer, and the blockchain security layer. To accommodate this model effectively, the authors introduce the novel proof of enhanced concept (PoEC) consensus mechanism. This approach employs homomorphic encryption to secure transactions, which are then outsourced to the fog layer or fog devices. This strategy mitigates various security threats, including collusion attacks, phishing attacks, and replay attacks, bolstering the resilience of each layer against such incursions. To bolster security measures further, our model adopts a hybrid-deep learning protocol for safeguarding electronic medical records against potential breaches while concurrently reducing latency through a decentralized fog computing system.
Deep Learning Techniques for Computer Vision
Authors: Stella Mary V. , Jayashree P. , Rajesh G. , Viswanath Shenoi V.
Published: September 2023

Object detection or shape reconstruction of an object from images plays a vital role in computer vision, computer graphics, optics, optimization theory, statistics, and various fields. The goal of object detection is to empower the machines to locate and identify the items or things in the given image or video. An object forms the image in human eyes or on a camera sensor is defined by its shape, reflectance, and illumination. This overview covers the estimation of the object shape, reflectance, illumination, recent object detection algorithms and data sets used in recent research works. The classic photometric stereo is aimed to reconstruct the surface orientation from the known parameters of reflectance and illumination in multiple images. Object detection approaches are used to find various pertinent objects in a given single image and location of the objects. There are various datasets for objection detection, some of them are addressed here.
Restorative Justice in Rural Schools
Authors: VanderPyl Taryn
Published: September 2023

There are conflicting descriptions of rural contexts, particularly as they relate to school discipline and juvenile justice. However, there are some consistencies that can guide research and intervention attempts for youth impacted by the juvenile justice system. Specifically, when compared to more urban settings, scholars have found consistent evidence in rural areas of more referrals to law enforcement by schools, more disproportionate minority contact with the juvenile justice system, and more punitive philosophy and outcomes overall. Further, there is consistent evidence in rural areas of challenges with access to resources for treatment and a lack of trauma-informed care, making evidence-based practices harder to implement and reentry more challenging compared to urban settings. This chapter provides recommendations and guidance for building on existing strengths of rural educators to develop restorative justice practices and reentry circles at schools that will mitigate the use of exclusionary discipline practices and support reentry following juvenile justice contact.
Optimizing Hyper Meta Learning Models
Authors: Devika G. , Karegowda Asha Gowda
Published: September 2023

Optimizing hyper meta learning models is a critical task in the field of machine learning, as it can improve the performance, efficiency, and scalability of these models. In this chapter, the authors present an epic overview of the process of optimizing hyper meta learning models. They discuss the key steps involved in this process, including task selection, model architecture selection, hyperparameter optimization, model training, model evaluation, and deployment. They also explore the benefits of hyper meta learning models and their potential future applications in various fields. Finally, they highlight the challenges and limitations of hyper meta learning models and suggest future research directions to overcome these challenges and improve the effectiveness of these models.
Procurement Misconduct and the Dynamics of Unethical Behavior in Organizations
Authors: Biazzin Cristiane
Published: September 2023

Procurement is a complex organizational role encompassing supplier selection, contract definition, and ensuring competitive pricing, quality, and delivery. However, these responsibilities often lead to diverse managerial stereotypes, ranging from passive followers of market dynamics to self-serving negotiators prioritizing personal gain over organizational interests. This chapter presents a unique single-case study on procurement fraud and misconduct, leveraging publicly available data. It explores the intricate nature and consequences of misconduct, including legal penalties, contract losses, and erosion of stakeholder trust. The study identifies control gaps that enable personal gain, and value of integrity-driven culture. Managers play a pivotal role as ethical exemplars, upholding standards, and mitigating risks. In response to misconduct, organizations take decisive action by terminating involved individuals and implementing new procedures, controls, and training programs. The findings underscore the need for continuous vigilance in promoting ethical practices within procurement.
Fraud and Corporate Governance
Authors: Inácio Helena , Santos Carlos
Published: September 2023

This bibliometric review analyzes the current literature on fraud and corporate governance, seeking to identify significant patterns and trends in the field besides relevant articles, authors, and journals. The study uses articles and conference papers from the Scopus database and provides insights into the importance of corporate governance in preventing fraudulent activity. The findings indicate a growing interest on the subject after 2002, the USA being a significant contributor to research in this field, and the (old) fraud triangle theory being widely used, because a lack of success in developing (new) fraud detection theories. China and India are worth some attention for the future and forensic accounting remains a trend, but the use of blockchain is emerging. The study highlights the need to investigate other databases beyond SCOPUS and refine analyses to compare results with the current study. Limitations include the use of only one database and the need to associate similar keywords. The study's justification lies in its contribution to existing knowledge in the subject field.
Cognitive Effects on Firefighters in Oklahoma From Their Initial Start of Service Till the Present
Authors: Bradley DeAnjelo J. L.
Published: September 2023

Working well under tremendous strain for relatively short periods is a topic of great importance in firefighting. This study put firefighters through a series of stressful solo smoke dives around a dark, winding simulation track to examine how their stress reactions affected their cognitive function. Male firefighters' heart rates were recorded during a smoke-diving exercise and compared with baseline readings and maximal rates. Male firefighters were used to studying these stressors. The firefighters thought aloud as they performed the smoke-diving maneuver to demonstrate their mental acuity. This study used a content analysis review of the literature published between the years 2017 to 2021 to define the problem, outline its complexities, and find needed solutions from dispersed sources.
Development of a Neural Network Model and Taguchi-Based Optimization for Dry Sliding Wear Performance of Al 6065 Alloy Reinforced with Nano SiC and Graphene Nanoplatelets
Authors: Pandiaraj V. , Thiyagarajan R. , Sivasakthi G. , Dhineshkumar K. , Sivanesh M. , Muguthan C.
Published: September 2023

The Al6065 alloy is widely used in various applications, including tubing for furniture, railway and bus structures, pylons, platforms, and pipelines. However, due to the wear experienced in these applications, it is essential to enhance the wear confrontation of this alloy. To address this issue, this research focuses on reinforcing Al6065 with nanoparticles of silicon carbide and graphene by means of the stir casting method. The wear behaviour of the alloy is studied by varying the rotational speed, load, and composition of reinforcement in the stir casting machine using Taguchi design of experiment. The rate of wear and friction coefficient are measured as responses. The obtained results are then analysed and optimized for the minimum of the output responses using S/N ratio analysis. Further, ANOVA is carried out to determine the influence of each parameter, and a model of the neural network is developed to predict the response. The findings indicate that cumulative the percentage of reinforcement enhances the wear resistance of the alloy. The optimized values of the rotational speed, load, and composition of reinforcement lead to improved wear resistance, with a corresponding decrease in the coefficient of friction. The ANOVA results reveal that the rotational speed and load significantly affect the responses, while the reinforcement composition has a moderate effect. The developed neural network model accurately predicts the response with a high degree of accuracy. The model can be used to optimize the wear behaviour of Al6065 alloy reinforced with nanoparticles of silicon carbide and graphene, as well as for prediction of the alloy's wear behaviour in various application environments. In conclusion, this research delivers a complete thoughtful of the wear behaviour of Al6065 alloy reinforced with nanoparticles of silicon carbide and graphene. The findings can be used to optimize the wear resistance and improve the routine of this alloy in various applications.
Determination of the Optimal Jar Mill Setting for Crushed Eggshells Used in LDPE Tile Creation
Authors: delos Reyes Ronald Allan S. , Higa Danah Patrice , Montuya Jonah Alyssa , Umantod Niera
Published: September 2023

In this study eggshells and low density polyethylene plastic (LDPE) wastes were reused to produce tiles. The eggshells were ground in a laboratory scale jar mill into the particle size of fine sand. The optimum grinding parameters were determined to be the setting that produced the highest mass of eggshell powder that was within the desired particle diameter size range of 0.425 mm (No. 40) and 0.075 mm (No. 200). A two to the three factorial design of experiment was used with variables of Time, Speed, and Ball Filling Ratio. The high and low values used in this study were 20 minutes and 10 minutes for the time, 250 rpm and 100 rpm for the speed, and 35% and 20% for the ball filling ratio. There were eight settings made with 3 trials per setting and one validation for the optimal setting produced. The eggshell powder produced by the optimal setting of the jar mill was used to create the LDPE-eggshell tiles. Four tiles were made for the three trials and for the validation part. The tiles were tested for its relative strength using the Compression Testing Machine. The researchers determined that eggshells and LDPE plastics may be formed into tiles and that the strength of the tiles that were produced by these materials exceeded the standard value set for this type of product.
The Effect of Reductor Type in Thermal Upgrading of Limonite
Authors: Bahfie Fathan , Manaf Azwar , Astuti Widi , Nurjaman Fajar , Prasetyo Erik
Published: September 2023

Thermal upgrading is the process for nickel extraction in selective reduction with holding temperature in low (300-500 °C). The effect and type of reductor are the main factor during this process. With those factors, this research will be finding the variation of reductor type. The first step is limonite and reductor characterization. Ni, Fe, Mg, Al, and Si levels in limonite are 1.4 Ni, 50.5 Fe, 1.81 Al, 4.86 Mg, and 16.5 Si weight percent, respectively. The iron oxide/oxyhydroxide content of limonite is 94.4 percent and 5.6 percent silicate. For reductor, those are graphite, palm kernel shell, and anthracite with carbon percentage 98, 77, and 68 %. From XRF, the optimum nickel grade is in the graphite and anthracite with 6.5 and 7 wt%. For phases, the ferronickel is appearing in the high intensity for the optimum reductor type and the microstructure is around 5-10 um for both. Moreover, the optimum reductor type are graphite and anthracite. Keyword: reductor type, limonite, phase, microstructure, thermal upgrading.
Satellite Remote Sensing for Wildlife Research in the Polar Regions
Authors: Lynch Heather J.
Published: September 2023

Abstract Wildlife research in the polar regions has historically been limited by the logistical constraints of site access, but recent developments in the use of satellite imagery for animal detection has unlocked new possibilities for pan-Arctic and pan-Antarctic monitoring
of animal populations. A range of different sensor systems have been used for wildlife research, but most have focused on optical sensors that collect data in the visible spectrum and can be directly interpreted similar to a photograph. These include medium-resolution sensors like Landsat
(30 m) and Sentinel-2 (10 m) and very high-resolution sensors such as Maxar's Worldview-2 (51 cm) and Worldview-3 (31 cm). These long-established satellite systems have been joined more recently by constellations of smaller satellites (so-called “Small Sats”) that offer imagery
of comparable spatial and spectral resolution to those operated by Maxar. This rapidly expanding portfolio of earth observation satellites offers the potential for a radical transformation of wildlife research in polar regions, but the sheer volume of data being collected now eclipses our
capacity for manual imagery interpretation. To meet this challenge, researchers are now harnessing advances in computer vision that, coupled with improvements in computing capacity, promise to deliver a new era in our ability to monitor polar wildlife.
Biofuels and Electrofuels as Alternative Green Fuels for Marine Applications: A Review
Authors: Saadeldin Mahmoud Abdel-Nasser , Elgohary Mohamed M. , Abdelnaby Maged , Shouman Mohamed R.
Published: September 2023

Abstract The International Maritime Organization (IMO) has imposed strict regulations to limit marine emissions because the maritime sector is expanding around the world, producing large amounts of emissions that are harmful to the atmosphere. Green alternative fuels, such
as biofuels derived from biomass and electrofuels derived from syngas sources, play critical roles in meeting IMO requirements for clean energy with zero emissions. This study presents a brief review of two types of green fuels: 1) the production of biofuels from biomass sources by using various
methods, such as the gasification process and the pyrolysis process, as well as the effectiveness of adding a variety of catalysts, and 2) electrofuels as a new method to oppose global warming by employing various carbon capture strategies and renewable hydrogen production based on water electrolysis.
Following that, the significant effect of using these green fuels in marine applications is discussed. Overall, the primary goal of this article is to provide data for researchers and industrialists interested in biofuels and electrofuels as promising alternatives to fossil fuels. A large
portion of the existing literature published in highly regarded journals, including the most recently published reports, is analyzed.
Research ethics during infectious disease outbreaks: A survey of African research stakeholders using the Ebola virus disease outbreak as a case
Authors: Tajudeen Raji , Silaigwana Blessing , Yavlinsky Alexei , Edwards Sarah J.L.
Published: September 2023

Conducting research during disease outbreaks can be ethically challenging as evidenced in the 2014‑2016 Ebola outbreak in West Africa and COVID‑19 pandemic. Yet, there has been little empirical research conducted for understanding the views and perspectives of different stakeholders regarding ethical issues in conducting research during disease outbreaks. This preliminary study was conducted to empirically explore African public health research stakeholders' views about research ethics issues during infectious disease outbreaks in Africa. We conducted an online survey of 330 participants attending the International Conference on Re‑emerging and Emerging Infectious Disease (ICREID) meeting that took place from 13‑15 March 2019 in Addis Ababa, Ethiopia to elicit their views on various research ethics complexities experienced in the 2014 Ebola outbreak. Study results revealed some divergent views on several ethical themes including: ethics of using unregistered interventions in outbreaks; acceptable study design; ethics review processes; risks‑benefit assessment; exclusion of pregnant women and children; and biological sample and data sharing. Majority (76.3%) of respondents felt that in the absence of available standard treatments or prevention modalities, the use of investigational interventions can be ethically justifiable if there is a strong scientific rationale and favorable risk‑benefit ratio. Regarding conventional placebo‑controlled trials during outbreaks with high case fatality rates, respondents that considered this unethical were more than three times those that felt such design were ethically justifiable. We were somewhat surprised that a majority (almost 60%) of respondents were satisfied with the exclusion of pregnant women and children in clinical trials during outbreaks. All respondents concurred with the prioritization of informed consent for research during an outbreak. Based on our findings, research ethics guidance is needed to equip research stakeholders in dealing with ethical complexities arising in the conduct of research during emerging disease outbreaks‑especially regarding using experimental interventions; placebo trial design; inclusion or justified exclusion of pregnant women and children; and biological sample/data sharing. The findings will be used in ongoing efforts of developing a consultative and coherent African‑centric framework to support ethical conduct of research for future emerging infectious disease outbreaks in Africa.
A review on Interstitial Lung Diseases: an overview from diagnosis to innovative therapies
Authors: Bertolina Carlotta , Bertolotti Marinella , Farotto Marianna , Giacchero Fabio , Ravera Silvia , Salio Mario , Pasquali Mercedes , Maconi Antonio
Published: September 2023

Interstitial Lung Diseases (ILDs) enclose a wide heterogeneous group of more than 200 pathological disorders, which are characterized by an inflammatory and/or fibrotic pattern in the respiratory tract. In recent years, significant developments in the understanding of their pathogenesis have led to considerable progress in the therapeutic field and in improving clinical outcomes. COVID-19 pandemic has also had an important impact on the course of interstitial disease, particularly that which developed following infection in both symptomatic and asymptomatic patients, as well as in patients with pre-existing interstitial disease prior to infection. The purpose of this review is to describe clinical, radiological and therapeutic features of some of the most common interstitial lung diseases, as well as the multidisciplinary diagnostic procedure that underlies an increasingly accurate diagnosis.
Diminished health and social outcomes among men who have sex with men who use drugs in Zimbabwe
Authors: Mapingure Munyaradzi , Chingombe Innocent , Dzinamarira Tafadzwa , Samba Chesterfield , Moyo Brian , Mugurungi Owen , Musuka Godfrey
Published: September 2023

No abstract available.
The miR-9-5p/CXCL11 pathway is a key target of hydrogen sulfide-mediated inhibition of neuroinflammation in hypoxic ischemic brain injury
Authors: Zhao Yijing , Li Tong , Jiang Zige , Gai Chengcheng , Yu Shuwen , Xin Danqing , Li Tingting , Liu Dexiang , Wang Zhen
Published: September 2023

JOURNAL/nrgr/04.03/01300535-202405000-00038/inline-graphic1/v/2023-09-28T063346Z/r/image-tiff

We previously showed that hydrogen sulfide (H2S) has a neuroprotective effect in the context of hypoxic ischemic brain injury in neonatal mice. However, the precise mechanism underlying the role of H2S in this situation remains unclear. In this study, we used a neonatal mouse model of hypoxic ischemic brain injury and a lipopolysaccharide-stimulated BV2 cell model and found that treatment with L-cysteine, a H2S precursor, attenuated the cerebral infarction and cerebral atrophy induced by hypoxia and ischemia and increased the expression of miR-9-5p and cystathionine β synthase (a major H2S synthetase in the brain) in the prefrontal cortex. We also found that an miR-9-5p inhibitor blocked the expression of cystathionine β synthase in the prefrontal cortex in mice with brain injury caused by hypoxia and ischemia. Furthermore, miR-9-5p overexpression increased cystathionine-β-synthase and H2S expression in the injured prefrontal cortex of mice with hypoxic ischemic brain injury. L-cysteine decreased the expression of CXCL11, an miR-9-5p target gene, in the prefrontal cortex of the mouse model and in lipopolysaccharide-stimulated BV-2 cells and increased the levels of proinflammatory cytokines BNIP3, FSTL1, SOCS2 and SOCS5, while treatment with an miR-9-5p inhibitor reversed these changes. These findings suggest that H2S can reduce neuroinflammation in a neonatal mouse model of hypoxic ischemic brain injury through regulating the miR-9-5p/CXCL11 axis and restoring β-synthase expression, thereby playing a role in reducing neuroinflammation in hypoxic ischemic brain injury.
Ferroptosis: a potential therapeutic target for stroke
Authors: Liu Chengli , Wang Guijun , Han Wenrui , Tian Qi , Li Mingchang
Published: September 2023

Ferroptosis is a form of regulated cell death characterized by massive iron accumulation and iron-dependent lipid peroxidation, differing from apoptosis, necroptosis, and autophagy in several aspects. Ferroptosis is regarded as a critical mechanism of a series of pathophysiological reactions after stroke because of iron overload caused by hemoglobin degradation and iron metabolism imbalance. In this review, we discuss ferroptosis-related metabolisms, important molecules directly or indirectly targeting iron metabolism and lipid peroxidation, and transcriptional regulation of ferroptosis, revealing the role of ferroptosis in the progression of stroke. We present updated progress in the intervention of ferroptosis as therapeutic strategies for stroke in vivo and in vitro and summarize the effects of ferroptosis inhibitors on stroke. Our review facilitates further understanding of ferroptosis pathogenesis in stroke, proposes new targets for the treatment of stroke, and suggests that more efforts should be made to investigate the mechanism of ferroptosis in stroke.
Acute intradialytic blood pressure changes in pediatrics; incidence, risk factors and management: single-center experience
Authors: Wagdy Reham , Thabet Mohamed A.E.H. , Baker Adel M. , El Sayed Shaymaa R.
Published: September 2023

Background

Despite Hemodialysis (HD) is a relatively safe procedure for End Stage Kidney Disease (ESKD) patients, Intradialytic (ID) hypotension and hypertension are frequently reported complications in many adults’ studies. However, little is known about acute intradialytic complications in children.

Objective

This study aimed to assess the incidence of acute ID blood pressure (BP) changes among children attending the HD unit at our institute. Furthermore, it assessed the possible risk factors and the management options.

Patients and methods

All children with ESKD on chronic HD were enrolled. A checklist was fulfilled every dialysis session over a six-month period, including patient’s demographic data, dialysis session details: frequency/week, duration of session, ultrafiltration volume, BP, vital signs, IVC diameter, dry weight and predialysis weight. All cases were subjected to echocardiography for estimation of cardiac function.

Results

Thirty-two patients with mean age of 9.16±2.48 years, and who dialyzed a total of 2678 sessions, were included in the current study. ID hypotension was the top (71.8%) of all complications with an incidence rate of 12.6% in all sessions, followed by ID hypertension (25.7%) with an incidence rate of 4.5% in all sessions. ID hypotension was significantly associated with males, with predialytic hypertension (P<0.001), high ultrafiltration rate (P0.033), and longer durations of sessions (mean >3.56 h±0.56 h) (P<0.001). However, less duration (mean < 3.33 h±0.55) and a lower percentage of ID weight loss were independent risk factors for the development of ID hypertension.

Conclusion

ID blood pressure changes are the most frequent complications in our study; hypotension is on the top of list (12.6% per sessions) followed by hypertension (4.5% per sessions). ID blood pressure is influenced by multiple risk factors; mainly by predialytic hypertension, duration of session and ID weight loss.
Role of reticulocyte haemoglobin content in diagnosis of iron deficiency anaemia
Authors: Badr Mohamed A. , Elashkar Shaimaa S.A. , Ismail Weaam A. , Abozid Asmaa A.A. , Hanna Dianna
Published: September 2023

Background

Multiple studies have demonstrated the value of detecting reticulocyte Hb (CHr) in peripheral blood samples for the diagnosis of iron insufficiency. It has been shown to be a reliable iron marker for gauging the efficacy of iron therapy and giving a precise assessment of iron status.

Aim of work

To improve the management of children with iron deficiency anaemia via evaluation of the significance of CHr in the diagnosis of IDA and comparing CHr with other iron parameters especially transferrin saturation and serum ferritin.

Methods

The study was a prospective, case-control study. It was conducted at the out-patient hematology clinic, pediatrics department, Zagazig University Hospital during six months from September 2022 to February 2023 after obtaining approval from Institutional Review Board (IRB #:9660-26-7-2022). Consecutive, non-selected 40 patients referred for anemia diagnosis were included in the study in addition to healthy 40 children of matched age and sex attending pediatric clinics for other causes than anemia who served as control group. All patients were subjected to full history taking, routine clinical examination, laboratory investigations including CBC and (CHr), iron parameters including serum iron, serum ferritin, TIBC, Transferrin saturation.

Results

The best cutoff of reticulocytes hemoglobin in diagnosis of anemia is ≥28.8%, area under curve 0.943, sensitivity 92.5%, specificity 82.5%, positive predictive value 84.1%, negative predictive value 91.7%, overall accuracy 87.5%. There is statistically highly significant difference between the studied groups regarding reticulocyte hemoglobin.

Conclusion

Our study demonstrates that CHr is a useful parameter that can be confidently used in the diagnosis of IDA. CHr can be a good predictor of IDA as evidenced by the correlations between the CHr and conventional haemtological and biochemical parameters of iron deficiency anemia.
Long-term remission of type 2 diabetes through intense lifestyle modification program – A case series
Authors: Tripathi Pramod , Kadam Nidhi , Vyawahare Anagha , Kuppusamy Maheshkumar , Vijayakumar Venugopal
Published: September 2023

ABSTRACT

Type 2 diabetes (T2D) remission is being widely accepted and documented as feasible through calorie restriction and bariatric surgery. Recent studies with lifestyle changes have also shown T2D remission; however, long-term remission through lifestyle modifications is not yet established. Though glycated hemoglobin (HbA1c) is a universally accepted indicator of glycemic status, oral glucose tolerance test (OGTT) would be a more robust marker in understanding whether the metabolic abnormalities in glucose metabolism have undergone complete remission as well. We present a case series of four patients enrolled in the Holistic Transformation Program, a lifestyle modification program, between 2016 and 2018. The intervention was a combination of a vegan diet, structured exercises, and stress management delivered over 12 months. All four patients successfully achieved T2D remission and cleared OGTT consecutively for a minimum period of 3 years. Our findings suggest that long-term T2D remission may be possible through lifestyle modification.
Training of physician graders on diabetic retinopathy screening using hand-held digital retinal imaging in a nonophthalmic setting
Authors: Piyasena Prabhath , Dhanapala Mangala , Banduthilake Kapila
Published: September 2023

Introduction:

There is no systematic diabetic retinopathy (DR) screening program in Sri Lanka. We aimed to train and assess physician graders as primary graders of DR screening, using hand-held retinal imaging, in a nonophthalmic setting.

Materials and Methods:

Selected general duty physicians in a tertiary level medical clinic underwent training to capture and grade DR independently, using a hand-held digital retinal camera (Zeiss Visuscout 100-Germany), at an outpatient medical department. Training curriculum was developed to identify the defined levels of DR, applicable to a resource poor nonophthalmic setting. Eight general physicians from a tertiary level medical department in the Western province of Sri Lanka underwent training.

Results:

All physicians were trained on knowledge and skills component and one-to-one direct observation was done by the study investigators to assess competency. Physicians underwent self-training until they were competent in capturing required retinal fields and grading them. 100% of them acquired skills on pupil dilatation and capturing required fields using the hand-held digital retinal camera. All physician graders underwent an assessment using a set of archived images in identifying DR signs, grading DR, and identifying the level of gradability. We selected the two best physicians (based on agreement levels, Kappa (k) =0.92 and k = 0.80, range k = 0.48–0.92) after the assessment, for a screening intervention validation study described elsewhere.

Conclusions:

At the medical clinic level, requirement exists for training and developing skills among physicians for DR screening and grading. The physicians can be effectively trained in DR screening using digital retinal imaging despite poor resources availability.
Investigating mutations in the genes GDF9 and BMP15 in Pelibuey sheep through the amplification-refractory mutation system with tetra-primers
Authors: Muñoz-García Canuto , Segura-León Obdulia L. , Gómez-Vargas Julio C. , González-Maldonado Juan , Quintero-Elisea Juan A. , Martínez-Montoya Juan F. , Cortez-Romero Cesar
Published: September 2023

Single Nucleotide Polymorphisms (SNP) or mutations are variations with a broad distribution in the genome and, as part of genetic studies, SNP allow the identification of allelic variants related to characteristics of economic importance in sheep production. However, the identification of SNP and their genotypes through sequencing is expensive, as it requires specialized materials and equipment. The objective of this study was to identify polymorphisms and their genotypes in the growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) genes in Pelibuey sheep using the tetra-primer amplification-refractory mutation system through polymerase chain reaction (T-ARMS-PCR). DNA extraction and amplification of BMP15 and GDF9 were conducted from blood samples contained in WhatmanTM FTATM cards from 60 multiparous Pelibuey ewes with reproductive records. The T-ARMS-PCR methodology allowed the identification of wild-type genotypes and mutated homozygous genotypes in polymorphisms G4 and G6 of GDF9, whereas mutations in the BMP15 gene were not found. These results were confirmed by sequencing. In conclusion, the T-ARMS-PCR methodology allowed the identification of mutated and wild-type genotypes in SNP G4 and G6 of GDF9, although no mutations were found in BMP15 in Pelibuey sheep. This technique was found to be reliable, rapid, and easily applied to identify polymorphic genotypes.
Нарушение скейлинга и возникновение массы в скалярных квантово-полевых теориях
Authors: Pismenskii Artem Leonidovich , Pis'mak Yury Mikhailivich
Published: September 2023

В безмассовых квантово-полевых теориях в логарифмических размерностях нарушается скейлинг. Рассматривается возможность интерпретации этого эффекта как спонтанного появления массы в рамках скелетных уравнений самосогласования с полным пропагатором в моделях с взаимодействиями $\varphi^3$, $\varphi^4$, $\varphi^6$ скалярного поля $\varphi$.
Запутанные состояния в простой модели квантовой электродинамики
Authors: Pis'mak Yury Mikhailivich
Published: September 2023

Рассматривается модель распространения двух частиц, возникших в одной точке пространства со скоррелированными поляризациями. Физические особенности этого процесса, описываемого в рамках квантовой электродинамики, обсуждаются в контексте квантовой информатики.
On the Need for Analytical Pedagogy in Poland. A review of a monograph by Alicja Żywczok and Bogumiła Bobik, Pedagogika analityczna. Od porządkowania wiedzy naukowej do odkrywania jej nowych obszarów [Analytical Pedagogy: From Organizing Scientific Knowledge to Discovering New Domains] Katowice: Wydawnictwo Uniwersytetu Śląskiego, 2022, ss. 156, ISBN 978-83-226-4240-5
Authors: Stępkowski Dariusz
Published: September 2023

the landscape of Polish scholarship on education. Its subject is intellectual pursuits consisting in categorizing, typologizing and systematizing concepts relevant to education professionals. The epistemic potential of philosophical logic provides the grounds for ordering our knowledge and thus a better handling of academic and educational work, but also discovering new and so far unexplored areas of cognition. Despite Poland’s noteworthy heritage of analytical research, such a sub-discipline is still lacking in the science(s) of education.

W recenzowanej monografii zaprezentowano koncepcję pedagogiki analitycznej jako nowej subdyscypliny w polskiej pedagogice akademickiej. Jej przedmiotem są czynności intelektualne polegające na kategoryzowaniu, typologizowaniu i systematyzowaniu pojęć specjalistycznych. Epistemiczny potencjał logiki filozoficznej sprawia, że czynności te umożliwiają uporządkowanie wiedzy, a przez to lepsze posługiwanie się nią w działalności naukowej i edukacyjnej, jak również odkrywanie nieoznaczonych do tej pory obszarów poznania. Pomimo dziedzictwa przeszłości w zakresie prowadzenia badań analitycznych wciąż brakuje w polskiej pedagogice takiej subdyscypliny.
Percorrendo trilhas, reescrevendo traçados: experiências de Pesquisa em Educação
Authors: Do Couto Regina Célia
Published: September 2023

Resumo: O intuito desse artigo é corroborar com as discussões no campo da pesquisa em educação. Apresento alguns estudos sobre as culturas realizados por mim enquanto formadora de professores e pesquisadora. Focalizo três momentos: primeiramente apresento observações que advém do meu contexto familiar e minha vivência como professora da educação básica. Exponho como a temática das culturas passa a se constituir como campo de indagações. Em seguida, trago a pesquisa de Mestrado que priorizou compreender as relações entre cultura e multiculturalismo. No terceiro, compartilho minha experiência no doutorado focalizando as diferentes culturas na região de fronteira do Brasil com o Uruguai. Esses estudos representaram possibilidades e desafios para que se enfrente discursos hegemônicos e se reconstrua no contexto da formação docente, perspectivas mais democráticas e inclusivas.
Historical Context of Environmental Education in the Amazon: a bibliographic review
Authors: Barbosa Manuel Saldanha , Lima Renato Abreu
Published: September 2023

The concern of scientists, educators, philosophers, poets and observers regarding man's distancing from nature dates back many centuries. In this sense, this work aimed to analyze the historical context of Environmental Education in Amazonas from 2008 to 2021, through a bibliographical review tracing the relevant points in this process, which contributed to the strengthening of EE in recent years. For data collection, the SCIELO, Google Academic, Google Scholar, Capes and Plataforma Sucupira databases were used, language was not limited in an attempt to obtain a relevant amount of theoretical reference, for data collection, information provided and disclosed without consider the period of publication. An average of 43 scientific works were found, including articles, dissertations and theses, of which only 20 were selected according to the inclusion and exclusion criteria. Of these works, all were published in Portuguese. With regard to Environmental Education in Amazonas, there is an urgent need for it to be participatory, transformative and emancipatory, in search of the transition from naive consciousness to critical consciousness. And for praxis to occur (reflection-action), the generating themes, proposed by Freire, can meet the confrontation of the society/culture and nature dichotomy and, in this sense, implement the attributes of EE in a Critical-Transforming perspective.
PROCES PRIVATIZACIJE I ZAPOSLENI (PRAVA I SLOBODE)
Authors: Kalajanović Snežana
Published: September 2023

The process of transition in Serbia has entered its third decade. Transition implies a break with the former economic pattern and appropriate to it institutional environment, i.e. the transition from one form of economic and social system (non- market or insufficiently market and totalitarian, i.e. populist) into another, completely different system (market and democratic). The privatization process is an important aspect of the transition of the economy from the public to the private sector. The paper focuses on the position and rights of employees during the privatization process and the consequences that privatization can have on the employees of companies that are being privatized, but also on the economy and the market in general. The paper lists the basic models of privatization, with an emphasis on the period after 2000. The most common causes and reasons for employee strikes were analyzed middle classes before, during and after the privatization of the company. The role is indicated unions in privatization and new forms of organizing dissatisfied strikers and participants in public protests. The paper will provide an insight into the negative outcomes of privatization according to the issue of employee rights, but also to show the positive effects not only for employees in privatized companies bur also more widely. The most important negative effects of privatization in Serbia could be reduced to the following:massive loss of jobs, increasing prevalence of precarious work, growth unemployment and poverty of citizens, marginalization of the importance and role of trade unions organizing. The faster the privatization, the more ineffective the strikes became. The positive effects are generally less numerous than the negative ones, but not the same negligible and represent novelties characteristic of a market-oriented society and pursuit of profit.
POLOŽAJ LOKALNOG OMBUDSMANA U PRAVNOM SISTEMU SRBIJE
Authors: Milivojević Jelena
Published: September 2023

The author deals with the position that the local ombudsman has in the legal system of Serbia, starting from the legislative regulation and the model by which his status is regulated by acts of local self-government. A special aspect of the work is dedicated to the status of the local ombudsman, which is conditioned, first of all, by the fact that his existence is optional. A special aspect of the work is dedicated to the status of the local ombudsman, which is conditioned, first of all, by the fact that it s existence is optional. The central issue in the work is focused on defining the position of the local ombudsman, the position that results from his authority and the position that results from the obligation of the decisions he makes as well as his responsibilities in the local self-government system. To this end, the paper will use a normative, comparative and historical method in order to point out the advantages and disadvantages of the position that local ombudsmen have in the legal system of Serbia.
PERTANGGUNGJAWABAN PIDANA PELAKU TINDAK PIDANA KEPEMILIKAN SENJATA PENIKAM ATAU PENUSUK BERUPA BADIK (Studi Putusan Nomor: 88/Pid.Sus/2021/PN Gdt)
Authors: Putra Dimas Pratama , Hakim Lukmanul , Ainita Okta
Published: September 2023

Siapapun orang yang membawa senjata tajam tanpa kekuatan menguasainya akan ancaman kriminal. Melalui itu, jika bukan untuk keperluan profesional atau kantor, sebaiknya tidak  membawa senjata tajam saat bepergian, karena untuk perlindungan diri. hal ini tidak bisa diterima sebagai alasan jika terjadi sesuatu. Apabila kedapatan membawa senjata tajam, diharapkan masyarakat dapat bersikap bijak agar tidak terjerat tindak pidana ancaman  membawa senjata tajam tanpa izin. Permasalahan dalam penelitian adalah bagaimana pertanggungjawaban pidana pelaku tindak pidana kepemilikan senjata penikam atau penusuk berupa badik berdasarkan Putusan Nomor: 88/Pid.Sus/2021/PN Gdt dan bagaimana pertimbangan hakim dalam menjatuhkan putusan terhadap kejahatan kepemilikan senjata penikam atau penusuk berupa badik berdasarkan Putusan Nomor: 88/Pid.Sus/2021/PN Gdt. Hasil penelitian dan pembahasan menunjukkan bahwa pertanggungjawaban pidana bagi pelanggar kepemilikan senjata tajam atau senjata tajam berupa badik didasarkan pada Putusan Nomor: 88/Pid.Sus/2021/PN Gdt adalah dengan menghukum terdakwa diatas dengan pidana penjara selama 1 (satu) tahun  3 (tiga) bulan dan menetapkan bahwa masa penangkapan dan  penahanan yang telah dijalani terdakwa dikurangi seluruhnya dari pidana tersebut. dikenakan. Pertimbangan hukum hakim dalam mengambil keputusan mengenai delik kepemilikan senjata tajam atau senjata tajam berbentuk badik didasarkan pada Putusan Nomor: 88/Pid.Sus/2021/PN Gdt Berikut ini, keadaan yang lebih memberatkan adalah tindakan si penyerang yang mengganggu ketertiban masyarakat dan mengancam keselamatan orang lain, sedangkan keadaan Keadaan yang meringankan adalah tindak pidana yang pertama kali dilakukan terdakwa dan  penyesalan terdakwa atas perbuatannya. diadili dan berjanji tidak akan mengulangi perbuatannya.
KAJIAN KRIMINOLOGI PENERAPAN SANKSI PEMBERIAN RASA MALU (SHAMING) TERHADAP PELAKU TINDAK PIDANA KORUPSI
Authors: Tansar Abdi , Manurung Mangasa , Siregar Syawal Amry
Published: September 2023

Permasalahan dalam penelitian ini adalah : Bagaimanakah konsep dan bentuk sanksi pemberian rasa malu (shaming) terhadap pelaku tindak pidana korupsi dalam perspektif kriminologi? Bagaimanakah penerapan sanksi pemberian rasa malu (shaming) terhadap pelaku tindak pidana korupsi dalam perspektif hukum pidana dan HAM? Apakah hambatan yang ditemukan dalam merumuskan dan menerapkan konsep sanksi pemberian rasa malu (shaming) terhadap pelaku tindak pidana korupsi? Kesimpulan, konsep pemberian rasa malu (shaming) terhadap pelaku tindak pidana korupsi dalam perspektif kriminologi terletak pada adanya pencelaan yang muncul dari masyarakat terhadap perbuatan korupsi. Pencelaan tersebut merupakan bagian reaksi masyarakat dan sekaligus sebagai suatu sanksi yang diberikan kepada pelaku korupsi yang disebut sebagai sanksi sosial. Ditinjau dari aspek kriminologi, sanksi pemberian rasa malu bagi para pelaku koruptor berupa pencelaan yang muncul sebagai reaksi masyarakat terhadap kejahatan korupsi belum menunjukkan adanya pencelaan yang maksimal terhadap perbuatan dan pelaku korupsi. Hambatan dalam merumuskan konsep sanksi sosial pemberian rasa malu (shaming) terhadap pelaku tindak pidana korupsi adalah belum adanya keinginan politik dari pemerintah bersama-sama dengan lembaga DPR untuk menjadikan sosial pemberian rasa malu sebagai bagian dari politik kriminal dalam menanggulangi kejahatan korupsi di Indonesia. Dengan belum dirumuskannya sanksi sosial berupa pemberian rasa malu bagi pelaku tindak pidana korupsi, maka penerapan sanksi sosial berupa pemberian rasa malu bagi terpidana korupsi juga belum dapat diterapkan.
GUGATAN GANTI KERUGIAN TERHADAP PERBUATAN INGKAR JANJI DALAM PERJANJIAN JUAL BELI TANAH (Analisis Putusan Perkara No. 1570 K/Pdt/2018)
Authors: Permana Rizki , Hamonangan Alusianto , Sinaga Lestari Victoria
Published: September 2023

Kedudukan para pihak dalam perjanjian jual beli menimbulkan hak dan kewajiban masing-masing. Suatu bentuk ganti rugi atas pelanggaran janji oleh salah satu pihak dalam kontrak jual beli, di mana salah satu pihak dalam kontrak jual beli dapat diminta untuk membatalkan kontrak dengan biaya, ganti rugi dan bunga. . Dapat juga dijelaskan bahwa pelanggar hanya dapat dimintai pertanggung jawaban ganti rugi hanya apabila ia diwajibkan untuk mengganti atau melaksanakan kontrak. Peninjauan kembali hakim terhadap putusan perkara no. 1570 K/Pdt/2018 tentang ganti kerugian atas ingkar janji dalam kontrak jual beli tanah dimana hukum diterapkan secara tidak benar Judex Facti (Pengadilan Negeri Bandung dan Pengadilan Tinggi Bandung) berpendapat bahwa surat Perjanjian antara penggugat dan tergugat tertanggal 12 September 2012 dipahami sebagai hubungan hukum antara para pihak dengan pinjaman dengan jaminan sertifikat d'homme (SHM). Bertepatan dengan penandatanganan perjanjian akuntansi, pada tanggal yang sama, 12 September 2012, dibuat perjanjian jual beli (PPJB). Jika dalam pasal 8 dicatat perjanjian utang antara lain jika debitur in casu fund tidak mampu membayar utang, maka PPJB akan mengajukan dan tanah tersebut akan menjadi milik penggugat SHM. Hal seperti itu dilarang oleh undang-undang, karena utang yang tidak dapat dibayar otomatis menjadi hubungan jual beli.