bluuebunny/crossref_metadata_2025 huggingface dataset:
Pt Nanoparticles on Multi-Walled Carbon Nanotubes with High CO Tolerance for Methanol Electrooxidation
Authors: Yang Pingping , Dong Shiming , Shu You , Wei Xuejiao
Published: October 2024

Anode catalysts are important for direct methanol fuel cells (DMFCs) of energy conversion. Herein, we report a novel strategy by ethylene glycol-based deep eutectic solvents (EG-DESs) for the fabrication of a multi-walled carbon nanotubes (MWCNTs)-supported Pt nanoparticles catalyst (referred to as Pt/CNTs-EG-DES). The Pt/CNTs-EG-DES catalyst provides an increased electrochemically active surface area (ECSA) and shows remarkably improved electrocatalytic performance towards methanol oxidation reaction compared to Pt/CNTs-W (fabricated in water) and commercial Pt/C catalysts. The improved performance is attributed to the generation of more Pt–O bonds which change the electronic states of the Pt atoms and the special node structure that obtains more active sites for a high CO resistance. This study suggests an effective synthesis strategy for Pt-based electrocatalysts with high performance for DMFC applications.
Organic–Inorganic Hybridization of Silkworm Cocoon Filaments Using Nano Pastes of Silica–Phosphate–M (M = Cu, Fe, or Al)
Authors: Karyasa I Wayan , Kusumawati Enike Dwi , Agustarini Retno , Andadari Lincah , Sari Herman
Published: October 2024

Inorganic–organic hybrid biomaterials have recently attracted much attention because of their widespread use. Silkworm cocoon filaments resulting from sericulture as prospective nanobiomaterials need to be improved, and their properties need to be used for broader purposes. This study was aimed at investigating methods for siliconization of silkworm cocoon filaments and characterizing their cocoon filament properties in terms of their yarn quality, natural dyeing, and antibacterial properties. Three methods of hybridization processes were used in this experiment, namely, in situ natural dyeing of silk yarns while silk filaments were spined, feed engineering through spraying the mulberry leaves with natural dyes and silica–phosphate–M (M = Cu, Fe, or Al) nano pastes, and a combination of both methods. The resulting cocoon filaments were characterized by their siliconization of filament fibers by using FTIR, XRD, and SEM-EDS methods. The yarn tensile strength, color quality, color fastness properties affected by the siliconization of silk filament fibers, and antibacterial properties were also investigated. Results showed that the combination method produced better siliconization of silk fibers, and, consequently, the better siliconization of silk fibers produced better natural dyeing as well as antibacterial properties of their resulting silk yarns.
Zibibbo Grape Seeds’ Polyphenolic Profile: Effects on Bone Turnover and Metabolism
Authors: Settino Mariagiovanna , Maurotti Samantha , Tirinato Luca , Greco Simona , Coppoletta Anna Rita , Cardamone Antonio , Musolino Vincenzo , Montalcini Tiziana , Pujia Arturo , Mare Rosario
Published: October 2024

Background: The consumption of seeds as food has become increasingly common due to their numerous health benefits. Among these, the seeds of the Zibibbo grape from Pantelleria, a native species of southern Italy, remain largely unexplored and are usually considered waste material from viticulture. Nevertheless, Zibibbo grape seeds may offer health benefits, particularly for the elderly and people with metabolic disorders, due to their potential content of beneficial compounds such as polyphenols. Methods: The Zibibbo grape seeds extract (ZSE) was characterized using UV-visible spectrophotometry and HPLC chromatography. The antioxidant activity of ZSE was measured by different colorimetric assays and Electronic Paramagnetic Resonance (EPR). Additionally, specific in vitro tests were conducted on human osteoblast cell lines (Saos-2 and MG63) aiming to evaluate the ZSE’s effects on bone turnover and metabolism. Western blotting was used to assess the impact on specific proteins and pathways related to bone health. Results: The ZSE contained almost ~3 mg/mL of carbohydrates and phenolic compounds, including rutin (~6.4 ppm) and hesperidin (~44.6 ppm). The extracts exhibited an antioxidant activity greater than 90% across all tests performed. Moreover, the Zibibbo seed extracts exerted a significant proliferative effect on the Saos-2 cell human osteoblast-like cell line, also modulating the phosphorylation of specific kinases involved in cell health and metabolism. Conclusions: Zibibbo grape seeds are rich in phenolic compounds, especially flavonoids with strong antioxidant and free radical scavenging properties. ZSE demonstrated beneficial effects on bone metabolism and osteoblast proliferation, suggesting potential for counteracting osteodegenerative conditions like osteoporosis. If confirmed through further studies, Zibibbo grape seed phenolic compounds could serve as an adjunctive therapy for osteoporosis, helping to slow aging and bone degeneration.
Pediatric Orally Disintegrating Tablets (ODTs) with Enhanced Palatability Based on Propranolol HCl Coground with Hydroxypropyl-β-Cyclodextrin
Authors: Cirri Marzia , Mura Paola A. , Maestrelli Francesca , Benedetti Simona , Buratti Susanna
Published: October 2024

Background: Propranolol, largely prescribed as an antihypertensive and antiarrhythmic drug in pediatrics, is characterized by a bitter taste and an astringent aftertaste. Currently, the therapy requires crushing of tablets for adults and their dispersion in water many times a day, leading to loss of dosing accuracy, low palatability, and poor compliance for both patients and caregivers. Objectives: This work aimed to exploit cyclodextrin complexation by cogrinding to develop orally disintegrating tablets (ODTs) endowed with reliable dosing accuracy, good palatability and safety, ease of swallowability, and ultimately better compliance for both pediatric patients and caregivers. Results: Different formulation variables and process parameters were evaluated in preparing ODTs. The technological and morphological characterization and disintegration tests were performed according to official and alternative tests to select the ODT formulation based on the drug Hydroxypropyl-β-cyclodextrin (HPβCD) coground complex form containing Pearlitol® Flash as the diluent and 8% Explotab® as the superdisintegrant, which demonstrated the highest % drug dissolution in simulated saliva and acceptable in vitro palatability assessed by the electronic tongue, confirming the good taste-masking power of HPβCD towards propranolol. Conclusions: Such a new dosage form of propranolol could represent a valid alternative to the common extemporaneous preparations, overcoming the lack of solid formulations of propranolol intended for pediatric use.
Effects of Different LED Spectra on the Antioxidant Capacity and Nitrogen Metabolism of Chinese Cabbage (Brassica rapa L. ssp. Pekinensis)
Authors: Li Jie , Liu Yubing , Wang Junwei , Liu Mingyue , Li Yanling , Zheng Jingyuan
Published: October 2024

Light quality optimization is a cost-effective method for increasing leafy vegetable quality in plant factories. Light-emitting diodes (LEDs) that enable the precise modulation of light quality were used in this study to examine the effects of red-blue (RB), red-blue-green (RBG), red-blue-purple (RBP), and red-blue-far-red (RBF) lights on the growth, antioxidant capacity, and nitrogen metabolism of Chinese cabbage leaves, while white light served as the control (CK). Results showed that the chlorophyll, carotenoid, vitamin C, amino acid, total flavonoid, and antioxidant levels of Chinese cabbage were all significantly increased under RBP combined light treatment. Meanwhile, RBG combined light treatment significantly increased the levels of amino acids but decreased the nitrite content of Chinese cabbage. In addition, RBF combined light treatment remarkably increased the amino acid levels but decreased the antioxidant capacity of Chinese cabbage. In conclusion, the addition of purple light to red-blue light was effective in improving the nutritional value and antioxidant capacity of Chinese cabbage. This light condition can be used as a model for a supplemental lighting strategy for leafy vegetables in plant factory production.
Synergistic Reinforcing Effect of Hazelnut Shells and Hydrotalcite on Properties of Rigid Polyurethane Foam Composites
Authors: Makowska Sylwia , Miedzińska Karolina , Kairytė Agnė , Strzelec Krzysztof
Published: October 2024

Recently, the development of composite materials from agricultural and forestry waste has become an attractive area of research. The use of bio-waste is beneficial for economic and environmental reasons, adapting it to cost effectiveness and environmental sustainability. In the presented study, the possibility of using hazelnut shell (HS) and hydrotalcite (HT) mineral filler was investigated. The effects of fillers in the amount of 10 wt.% on selected properties of polyurethane composites, such as rheological properties (dynamic viscosity, processing times), mechanical properties (compressive strength, flexural strength, hardness), insulating properties (thermal conductivity), and flame-retardant properties (e.g., ignition time, limiting oxygen index, peak heat release), were investigated. Polyurethane foams containing fillers have been shown to have better performance properties compared to unmodified polyurethane foams. For example, the addition of 10 wt% of hydrotalcite filler leads to PU composite foams with improved compression strength (improvement by ~20%), higher flexural strength (increase of ~38%), and comparable thermal conductivity (0.03055 W m–1 K–1 at 20 °C). Moreover, the incorporation of organic fillers has a positive effect on the fire resistance of PU materials. For example, the results from the cone calorimeter test showed that the incorporation of 10 wt% of hydrotalcite filler significantly reduced the peak of the heat release rate (pHRR) by ca. 30% compared with that of unmodified PU foam, and increased the value of the limiting oxygen index from 19.8% to 21.7%.
Electrospun Cellulose Acetate/Poly(Vinyl Alcohol) Nanofibers Loaded with Methyl Gallate and Gallic Acid for Anti-Staphylococcus aureus Applications
Authors: Jiamboonsri Pimsumon , Sangkhun Weradesh , Wanwong Sompit
Published: October 2024

Methyl gallate (MG) and gallic acid (GA) are natural compounds with potent activity against methicillin-resistant Staphylococcus aureus (MRSA), a significant global health concern. In this study, MG and GA were incorporated into cellulose acetate (CA) blended with poly(vinyl alcohol) (PVA) to create electrospun nanofibers aimed at combating both methicillin-susceptible S. aureus (MSSA) and MRSA. Key electrospinning parameters—DC voltage, injection flow rate, and syringe tip–collector distance—were optimized, with the best conditions being a 1.5 mL/h flow rate, 30 cm distance, and 20 kV voltage. The resulting nanofiber mats were characterized by SEM, FTIR, DSC, tensile strength testing, contact angle measurement, swelling behavior, and release profiling. Antibacterial properties were assessed using the agar diffusion test. The obtained nanofibers had diameters ranging from 879.33 to 906.13 nm. Among the samples, MG-GA-CA/PVA exhibited the highest tensile strength, good flexibility, and improved stiffness, which was related to enhanced thermal stability and chemical interactions as shown by DSC and FTIR analyses. This formulation also displayed excellent hydrophilicity, swelling properties, and a consistent release profile over 8 to 24 h. Furthermore, MG-GA-CA/PVA showed superior antibacterial activity against both MSSA and MRSA, suggesting its potential as a strong, flexible, and effective anti-S. aureus material.
Fish, Fetishization, and Faith in the Arctic Ocean
Authors: Grau Marion , Sjöberg Lovisa Mienna
Published: October 2024

The ocean is a site of energy, space, movement, depth, and extraction. The biblical creation account begins there, with the energy of movement of the Spirit over the Deep. The exploitation of the ocean can be read as a desecration of the Deep, of divine presence and creativity, where beings of the deep roam. Many of these beings are beyond human knowledge, known only to the Creator. Many disturbances of the ocean floor and ocean dwellers have already occurred; penetrating even deeper into the ocean is a form of sacrilege. Extractive politics in the Arctic Ocean and in Northern Sápmi continue following decades of overfishing, poaching, and repression of indigenous coastal traditions. The Sámi tradition and ecological theologies offer a different way of looking at coastal and ocean regions. As tools to counter the calls for endless extraction, we offer narratives that highlight the importance of the coastal Sámi oral tradition and a decolonial ecotheology of a protective apophasis of the Deep. Countering extraction involves rejecting a hermeneutics of commodity fetish that distorts the ocean and those that live and travel within it by framing them as endlessly extractable. This article seeks to resist the extraction of oceanic waters and remind us of ways to respect ocean-dwelling species, the ocean, and ourselves in a time where we are facing the sixth great extinction.
The Phenomenology of Affirmation in Nietzsche and R. Mordechai Yosef Leiner of Izbica
Authors: Hefter Herzl
Published: October 2024

Nietzsche is the world’s most (in)famous atheist, bearer of the monumental tiding of the Death of God. His works contain biting critiques of Christianity and, to a lesser degree, of Judaism as well. Rabbi Mordechai Yosef Leiner of Izbica [=RMY] (1800–1854) was a leading Hasidic master in 19th century Poland. Despite their seemingly incongruent world views and backgrounds, bringing the German philosopher and the Polish Rebbe into conversation bears significant fruit. The significance of my study is two-fold. First, based upon similar philosophical moves by both Nietzsche and RMY, I aim to establish a philosophical foundation upon which to create a secular religious space which, beyond the local discussion around Nietzsche and RMY themselves, is of vital importance in a world continuously divided along inter-religious and secular-religious grounds. In addition, I will sharpen what we mean when we discuss the “religiosity” of Nietzsche and how this religiosity may confront nihilism. I believe that Nietzsche’s orienting insight that God is dead can serve as an inspiration to create a phenomenologically religious “space” devoid of metaphysical and transcendental assertions and that there is a Hasidic master willing to meet him there. The quest of RMY was to reveal a Torah bereft of “Levushim”, that is to say, bereft of the familiar Jewish and kabbalistic mythical trappings. When the traditional Christian and Jewish myths which refer to a transcendent reality are discarded, the search for meaning is relocated onto the immanent stage of human (“All too Human”) phenomenology.
Between Whale Teeth and the Moral Uses of the Sea: Considering Religion in the US Whaling Industry’s Extractive Zone
Authors: Callahan Richard J.
Published: October 2024

This article argues that the nineteenth century US whaling industry provides an oceanic perspective on extractive zones that illuminates their multi-sited, multiscalar nature where the local and global are deeply entangled. Further, I suggest that viewing this process through the underexamined lens of religion can contribute to a fuller understanding of the widespread, often neglected, impacts of extractivism. I take an 1845 sermon by liberal Protestant theologian Horace Bushnell, “A Discourse on the Moral Uses of the Sea,” read alongside the labors of the American whaling industry, as a mid-nineteenth century moment to consider the concealment of the natural resource extraction that is necessary for the production of the conditions of possibility for the imagination of “civilization” ideologically and theologically in the mid-nineteenth century. I look to the journey of whale teeth as they move between waste, items of trade in a global capitalist market, and powerful ritual objects in Fiji, assessing how the extractive zone as a contact zone also transforms religion, which in turn can be a location of agency and resistance. The article calls attention to the critical entanglements of indigenous and settler worlds, whose stories cannot be told separately from one another.
Kinematic Reliability of Manipulators Based on an Interval Approach
Authors: Lara-Molina Fabian Andres , Gonçalves Rogério Sales
Published: October 2024

Robotic manipulators inevitably experience the impact of uncertainties and errors, such as dimensional tolerances and joint clearances. Therefore, this paper proposes a novel method based on an interval approach to evaluate the kinematic reliability of manipulators. Kinematic reliability quantifies the probability of positioning errors that fall within allowable boundaries. As a result, reliability evaluates the probability that the interval end-effector error produced by dimensional tolerances exceeds an acceptable rate. The proposed reliability index is based on the interval error that conveys an alternative approach to the kinematic reliability methods based on probabilistic frameworks reported in the literature based on probabilistic approaches. The obtained numerical results demonstrate the viability of the proposed methodology by evaluating the reliability of a serial manipulator subjected to joint clearances and a parallel manipulator with dimensional tolerances.
Identifying the Challenges in the Detection and Protection of Child Victims of Human Trafficking in Spain: A Case Study of the Southern European Border
Authors: Verdasco Martínez Raquel , García-Vázquez Olaya , Estrada Villaseñor Cecilia , Dubin Adam
Published: October 2024

Despite the improvements in enhanced child protection, there is an increasing concern about the vulnerability and cases of child trafficking in Spain, the southern gateway to Europe from the African continent. Analyzing 23 interviews with professionals in the field, this article identifies the factors that contribute to high levels of child trafficking in Spain. This study identifies three primary results: (1) The dangers of residential childcare as places of recruitment; (2) The southern European and Spanish border as a place of elevated risk for the recruitment of children; (3) The stereotypes regarding child trafficking make invisible male victims, other types of trafficking for non-sexual purposes, domestic trafficking, and individual trafficking. Therefore, it remains imperative to advance a set of policies that: (i) invest in specific residential childcare resources for child victims either alone or with family members; (ii) invest in smaller residential childcare to prevent abuse; (iii) invest in mentoring programs for children previously under state guardianship; (iv) improve the working conditions and the training of residential childcare staff; (v) increase the visibility and diversity of child trafficking while avoiding stereotypes; (vi) improve the regional coordination; (vii) invest in campaigns to inform children about the dangers involved in running away, exploitation and abuse.
Sustaining Economic Growth: E-Service Quality’s Role in Fostering Customer Loyalty in Nigeria SMEs
Authors: Madueke Chioma Judith , Eyupoglu Serife
Published: October 2024

The aim of this study is to investigate the impact of e-service quality on customer loyalty with customer satisfaction as a mediator in the small and medium-sized business sector in Nigeria. The dimensions investigated in this study are reliability, web design, trust, empathy, convenience, and cultural inclusion. To the best of the researchers’ knowledge, there has not been any research done on this subject investigating the above dimensions among Nigerian SMEs across various cultural groups. Therefore, this study fills this gap by investigating the impact of culture, web design, trust, empathy, convenience, and reliability on SMEs. A questionnaire was used for the purpose of the study to collect primary data. Four hundred and ninety-two responses were obtained from the respondents, who were age 20 and above. The survey was carried out online across the four major poles of Nigeria (east, west, north, and south) because of their varying and distinct cultural background. The data collected were analyzed using SPSS 28, Smart PLS 4 and AMOS 29 for descriptive analysis and structural equation modeling to test the research model. The results showed that the service quality dimensions have a positive significant impact on customer satisfaction and also show that customer loyalty is positively impacted by customer satisfaction.
Factors Influencing Consumer Upcycling Behavior—A Study Based on an Integrated Model of the Theory of Planned Behavior and the Technology Acceptance Model
Authors: Ma Kaiyue , Liu Bohan , Zhang Jie
Published: October 2024

In the context of the global climate change debate, changing consumer awareness and guiding them towards sustainable lifestyles should be key considerations. This study investigates the factors influencing consumers’ upcycling behaviors by conducting research and collecting 336 valid questionnaires at the “Eco Blet” sustainable design exhibition and workshop held at Livat Beijing (Ingka Centres Beijing). The survey results revealed that consumers’ upcycling behavior is significantly influenced by subjective norms, perceived behavioral control, perceived usefulness, and attitudes. In addition, individuals with higher levels of education and those with annual incomes of less than 100,000 RMB and more than 400,000 RMB are more likely to engage in upcycling. The empirical analysis of consumer upcycling behavior is conducted using structural equation modeling (SEM), and the theory of planned behavior (TPB) and technology acceptance model (TAM) are integrated into a comprehensive framework. This research provides both theoretical support and practical insights for promoting sustainable consumer behaviors, contributing significantly to carbon emission reduction.
Design for Circular Manufacturing and Assembly (DfCMA): Synergising Circularity and Modularity in the Building Construction Industry
Authors: Dewagoda Kaveesha Gihani , Ng S. Thomas , Kumaraswamy Mohan M. , Chen Ji
Published: October 2024

Modular construction is emerging into the limelight in the construction industry as one of the front-running modern methods of construction, facilitating multiple benefits, including improved productivity. Meanwhile, Circular Economy (CE) principles are also becoming prominent in the Building Construction Industry (BCI), which is infamous for its prodigious resource consumption and waste generation. In essence, the basic concepts of modular construction and CE share some commonalities in their fundamental design principles, such as standardisation, simplification, prefabrication, and mobility. Hence, exploring ways of synergising circularity and modularity in the design stage with a Whole Life Cycle (WLC) of value creation and retention is beneficial. By conducting a thorough literature review, supported by expert interviews and brainstorming sessions, followed by a case study, the concept of Design for Circular Manufacturing and Assembly (DfCMA) was proposed to deliver circularity and modularity synergistically in circularity-oriented modular construction. This novel conceptualisation of DfCMA is envisaged to be a value-adding original theoretical contribution of this paper. Furthermore, the findings are expected to add value to the BCI by proposing a way forward to synergise circularity and modularity to contribute substantially towards an efficient circular built environment.
Applying Systems Thinking to Sustainable Beef Production Management: Modeling-Based Evidence for Enhancing Ecosystem Services
Authors: Tedeschi Luis O. , Johnson Demian C. , Atzori Alberto S. , Kaniyamattam Karun , Menendez Hector M.
Published: October 2024

We used systems thinking (ST) to identify the critical components of beef cattle production through the lens of ecosystem services (ES), offering a holistic approach to address its adverse externalities. We identified eight critical feedback loops in beef production systems: (i) grazing and soil health, (ii) manure management and soil fertility, (iii) feed efficiency and meat production, (iv) water use and soil moisture, (v) cultural services and community engagement, (vi) energy use, (vii) carbon sequestration and climate regulation, and (viii) environmental impact. Our analysis reveals how these interconnected loops influence each other, demonstrating the complex nature of beef production systems. The dynamic hypothesis identified through the loops indicated that improved grazing and manure management practices enhance soil health, leading to better vegetation growth and cattle nutrition, which, in turn, have a positive impact on economic returns to producers and society, all of which encourage the continuation of interlinked beef and ecosystem stewardship practices. The management of beef production ES using ST might help cattle systems across the globe to contribute to 9 of the 17 different United Nations’ Sustainable Development Goals, including the “zero hunger” and “climate action” goals. We discussed the evaluation framework for agrifood systems developed by the economics of ecosystems and biodiversity to illustrate how ST in beef cattle systems could be harnessed to simultaneously achieve the intended environmental, economic, social, and health impacts of beef cattle systems. Our analysis of the literature for modeling and empirical case studies indicates that ST can reveal hidden feedback loops and interactions overlooked by traditional practices, leading to more sustainable beef cattle production outcomes. ST offers a robust framework for enhancing ES in beef cattle production by recognizing the interconnectedness of ecological and agricultural systems, enabling policymakers and managers to develop more effective and sustainable strategies that ensure the long-term health and resilience of humans and ES.
Land Use Changes and Spatiotemporal Distribution of Domestic Water Consumption in the Northern Slope of Tianshan Mountains
Authors: Zhang Menglin , Li Zhao , Chen Gang , Li Fadong
Published: October 2024

Rapid population growth and subsequent urbanization pose significant challenges of water shortage in arid regions. As an important area along the One Belt and One Road line, the Northern Slope of Tianshan Mountains (NSTM) has suffered from water shortages owing to rapid urbanization in recent decades. To conserve water resources and protect the ecosystem, understanding the temporal and spatial variations of the domestic water consumption, availability, and its influencing factors is essential. According to water resource regionalization and its characteristics in NSTM, it was divided into three sections, namely the west section, the middle section, and the east section. In addition, this work characterized the temporal and spatial variation of domestic water consumption in NSTM with a focus on the understanding of the influence of urbanization on domestic water consumption from 1990 to 2020 based on three sections. The results showed that during this period of time, construction land use increased by 2256 km2 corresponding to the population increase of 158.58 × 104. Subsequently, the total domestic water consumption increased from 7.55 × 107 m3 in 1990 to 2.60 × 108 m3 in 2020. The eastern section demonstrated steady growth, while the western and middle sections experienced larger fluctuations in domestic water consumption. Urbanization has been identified as a significant factor influencing the shift in domestic water consumption. This study offers a scientific foundation for the sustainable management of water resources in arid areas.
Enhancing the Prediction of Influent Total Nitrogen in Wastewater Treatment Plant Using Adaptive Neuro-Fuzzy Inference System–Gradient-Based Optimization Algorithm
Authors: Ikram Misbah , Liu Hongbo , Al-Janabi Ahmed Mohammed Sami , Kisi Ozgur , Mo Wang , Ali Muhammad , Adnan Rana Muhammad
Published: October 2024

For the accurate estimation of daily influent total nitrogen of sewage plants, a novel hybrid approach is proposed in this study, where a gradient-based optimization (GBO) algorithm is employed to adjust the hyper-parameters of an adaptive neuro-fuzzy system (ANFIS). Several benchmark methods for optimizing ANFIS parameters are compared, which include particle swarm optimization (PSO), gray wolf optimization (GWO), and gradient-based optimization (GBO). The prediction accuracy of the ANFIS-GBO model is evaluated against other models using four statistical measures: root-mean-squared error (RMSE), mean absolute error (MAE), and Nash–Sutcliffe efficiency (NSE), and coefficient of determination (R2). Test results show that the suggested ANFIS-GBO outperforms the standalone ANFIS, hybrid ANFIS-PSO and ANFIS-GWO methods in daily influent total nitrogen prediction from the sewage treatment plant. The ANFIS, ANFIS-PSO, ANFIS-GWO, and ANFIS-GBO models are evaluated using seven distinct input combinations to predict daily TNinf. The results from both the testing and training periods demonstrate that these models, namely ANFIS, ANFIS-PSO, ANFIS-GWO, and ANFIS-GBO, exhibit the highest level of accuracy for the seventh input combination (Qw, pH, SS, TP, NH3-N, COD, and BOD5). ANFS-GBO-7 reduced the RMSE in the prediction of ANFIS-7, ANFIS-PSO-7, and ANFIS-GWO-7 by 21.77, 10.73, and 6.81%, respectively, in the test stage. Results from testing and training further demonstrate that increasing the number of parameters (NH3-N, COD, and BOD) as input improves the models’ ability to make predictions. The outcomes show that the ANFIS-GBO model can potentially be suggested for the daily prediction of influent total nitrogen (TNinf) in full-scale wastewater treatment plants.
Analysis of the resource base and competition of business tourism in Moscow
Authors:   Patrice Lumumba Russian People’s Friendship Universit, Moscow, Magtymova P. N.
Published: October 2024

This paper analyzes the resource base in the context of the competitiveness of business tourism in Moscow. It considers the key elements that form the infrastructure of business tourism, such as the hotel sector, transport accessibility, service level and the presence of business centers. Particular attention is paid to a comparative analysis with other large cities, which helps to identify the strengths and weaknesses of Moscow’s offer. It also considers factors influencing the development of business tourism, including macroeconomic conditions, trends in event organization and digitalization of services. The importance of cooperation between government and the private sector to create an attractive environment for international business clients is emphasized. In conclusion, recommendations are formulated for optimizing the city’s resource base to increase competitiveness and improve the image of Moscow as one of the leading destinations for business tourism.
Features of the formation of tourism product in Mongolia
Authors:   Higher School of Management, Peoples’ Friendship University of Russia named after Patrice Lumumba, Moscow, Akheli Tileukhan
Published: October 2024

Mongolia is a unique tourist destination that attracts travelers with its culture, natural landscapes and historical heritage. The article examines the features of the formation of the tourism product in Mongolia, including key aspects that contribute to the successful development of tourism in this country.
Analysis and development of creation of pr – strategy in tourism with artificial intelligence.
Authors:   Patrice Lumumba Russian People’s Friendship University, Moscow, Balev N. N. , Zeveke O. Yu. ,   Patrice Lumumba Russian People’s Friendship University, Moscow
Published: October 2024

New trends in creating a PR strategy in tourism using a neural network are considered, and an overview of the neural network functions that are in demand in creating a PR campaign is made.
Some tools for assessing the customer focus of the company running community
Authors:   Higher School of Management, Patrice Lumumba Peoples’ Friendship University of Russia, Moscow, Samokhina P. V.
Published: October 2024

The article examines the importance of customer-centricity for modern companies operating in a highly competitive environment. Particular attention is paid to the relevance of this concept for running communities — a dynamically developing segment of the physical culture and sports market. The need to develop effective tools for assessing and managing customer-centricity within running communities is emphasized.
Oil and Gas Industry of India: Russian Aspect
Authors:   Russian Foreign Trade Academy of the Ministry of Economic Development of the Russian Federation (RFTA), Moscow, Kondratov D. I.
Published: October 2024

Rather high rates of GDP growth (compared to the world average and other Asian countries) and real incomes of the population, combined with ongoing policies of industrialization and urbaniza-tion, make India one of the most attractive markets for commodities. The country needs natural resources, mainly oil and gas. Among the key areas of development of the national economy are the oil and gas producing and processing industries. Cooperation in the energy sector between Russia and India is developing steadily and progressively, important joint projects are also being implemented. The Russian Federation exports all types of raw materials, with the exception of pipeline natural gas. In 2023, oil imports from Russia, according to the Ministry of Commerce and Industry of India, amounted to 82.21 million tons (about 1.64 million barrels per day), which is 2.61 times higher than in 2022. During the same period, 9.09 million tons of Russian oil prod-ucts were delivered (+2.39 times to the level of 2022), more than 70 % of which were fuel oil. India is also among the largest importers of Russian coal and СNG. In 2023, India imported about 23.21 million tons of Russian coal (+28.8 % to the level of 2022) and 0.41 million tons of CNG (equal to the level of 2022). As you can see, Russia is interested in increasing the export of commodities to India due to the fact that the latter is an emerging economy and acts as an ex-panding market for natural fuels for the needs of households and industry. In addition, owing to the sanction restrictions imposed on Russian companies and the need to diversify supplies, in terms of foreign economy Russia takes particular interest in cooperation with Indian partners. Let’s study India’s energy policy, especially its oil and gas market, below.
Influencia del cuarzo y materiales silíceos en las propiedades físico-mecánicas del hormigón
Authors: Calle López Cristhian Jesús , Salazar Rojas Alexander Joseph
Published: October 2024

La influencia del cuarzo y otros materiales silíceos en las propiedades físico-mecánicas del hormigón es un tema relevante en el ámbito de la ingeniería civil y la construcción. El hormigón, como material de construcción, se compone principalmente de áridos, agua y un aglomerante. El objetivo del artículo es indagar la influencia del cuarzo y materiales silíceos en las propiedades físico-mecánicas del hormigón, identificando la dosificación y su resistencia a la compresión. A través de un enfoque cualitativo se realizó una revisión sistemática de artículos científicos. El análisis se basó en 42 publicaciones recopiladas durante el estudio, 13 de Scielo, 10 ScienceDirect, 2 Redalyc y 17 en otros. Se concluye que, los estudios analizados muestran que la adición de cuarzo triturado al hormigón f’c 210 puede mejorar su resistencia a la compresión en ciertos casos, pero también puede disminuir la resistencia en otros, siendo la dosificación del 20% de cuarzo la que presenta mejores resultados. Es importante evaluar los materiales antes de usarlos en construcción.
La facultad del Estado para regular el ejercicio del derecho a recurrir
Authors: García Flores Adriana Lisseth , Yugcha Quinatoa Angélica Marlene , Vásquez Chicaiza Franklin Patricio , Jara Rubio Silvia Cristina , Galarza Castro Christian Xavier
Published: October 2024

El derecho a recurrir es un derecho fundamental inherente a la persona humana, reconocido en diversos niveles normativos. El objetivo del estudio es comprender la facultad del Estado ecuatoriano para regular el ejercicio del derecho al recurso. El enfoque seleccionado es cualitativo, del paradigma interpretativo y método hermenéutico. Se adopta el método documental jurídico, basándose en una revisión sistemática de bibliografía fundamental relacionada con el tema. Los resultados muestran que, en consonancia con el principio de convencionalidad, el Estado ecuatoriano tiene la facultad de regular el derecho a recurrir, siempre y cuando se respeten los criterios de legalidad, necesidad y proporcionalidad establecidos por la CIDH. Las conclusiones señalan que los precedentes de la Corte Constitucional han aceptado ciertas regulaciones sobre el derecho a recurrir, manifestando que no es un Derecho absoluto y le otorga la facultad al legislador para poder limitarlo. Aunque el derecho a interponer recursos está protegido, las limitaciones deben ser cuidadosamente valoradas para proteger otros derechos.
Seguridad jurídica y protección de datos en Ecuador: validez legal de los Smart contract
Authors: Herrera Herrera Gilda Cecilia , Requelme Lojan Marcia Alexandra , Morales Castro Samuel
Published: October 2024

El presente estudio se centra en la relevancia de la seguridad jurídica y la protección de datos en el contexto específico de los Smart Contract en Ecuador. El objetivo de la investigación es Analizar la validez legal de los Smart Contract tomando como referente la regulación de la seguridad jurídica y la protección de datos personales, como una garantía de los derechos de las partes negociadoras y de terceros interesados. El método utilizado es el exegético, asi como una revisión documental y normativa con los datos obtenidos. Los resultados reflejan que, aun existiendo normas legales en seguridad jurídica y protección de datos, los Smart Contract no tienen una base sólida en el marco legal del Ecuador. Se concluye que los Smart Contract son una evolución en base a tecnología de los contratos tradicionales, existiendo la necesidad de implementar una legislación de rigor al respecto
Notificación oportuna en medidas de protección para víctimas de violencia de género
Authors: Chuya Oviedo Nathaly Belen , Uyaguari Ramirez Paco Eduardo , Ramón Merchán Mónica Eloiza
Published: October 2024

A pesar de la creciente atención a la violencia de género, la efectividad de las medidas de protección sigue siendo un tema de debate. El estudio tiene como objetivo analizar la falta de notificación oportuna al denunciado al otorgamiento de medidas de protección en delitos de violencia de género en Ecuador. El enfoque es cualitativo. Adicionalmente, se enmarca en una metodología jurídica de tipo dogmático, se aplicó la técnica de revisión documental. Dentro de la muestra cualitativa se encuentran La Constitución y las sentencias de la Corte Constitucional. Los resultados revelan serias deficiencias en la implementación efectiva de medidas especialmente en lo que respecta a la notificación oportuna al denunciado. Se concluye que, la adopción de tecnologías avanzadas y la mejora en la capacitación del personal judicial y policial pueden ser claves para mejorar la eficacia del sistema de notificación, asimismo, las medidas de protección destinadas a salvaguardar a las víctimas requieren una implementación y seguimiento diligentes para ser efectivas.
Risks of generative artificial intelligence in financial intermediation and approaches to their assessment
Authors: Zver'kova T.
Published: October 2024

The subject of the study is the impact of generative artificial intelligence (GenAI) on financial intermediation and associated risks. The purpose of the study is to assess the current state of GenAI adoption in financial intermediation, identify potential risks and challenges, and explore the implications of increased use of these technologies. The relevance of the study is due to the rapid development of artificial intelligence (AI) technologies and their increasing impact on financial intermediation, which requires a comprehensive analysis and understanding of possible risks and benefits. The research methodology is based on the study of existing research on this topic,identification of current approaches to identifying risks, empirical analysis, including collection and processing of lists of risks of using GenAI and associated consequences. It is concluded that the variability of definitions in risk assessment GenAIcan create significant obstacles to consistency and coordination of actions between various market participants. Moreover, the lack of unified assessment criteria can lead to underestimation or overestimation of potential threats, which increases the likelihood of system failures and increases risks to the sustainability of the financial intermediation system as a whole.

As part of the preparation of the study, responses generated by ChatGPT about the assessment of the risks posed by GenAI were used.
Harnessing Nanotechnology for Gout Therapy: Colchicine-Loaded Nanoparticles Regulate Macrophage Polarization and Reduce Inflammation
Authors: Zhang Ning , Zhao Lanqing , Li Jinwei , Li Hongxi , Chen Yu
Published: October 2024

Gout is a disease caused by hyperuricemia, characterized by inflammation reactions triggered by macrophage polarization. Colchicine is a commonly used drug for gout treatment, but its mechanism of action remains unclear. The aim of this study was to investigate the regulatory effect of colchicine on macrophage polarization to enhance the therapeutic effectiveness against gout inflammation. To accomplish this, a mouse model was established, and peripheral blood mononuclear cell samples were collected. Single-cell RNA sequencing was employed to reveal cellular heterogeneity and identify key genes. Molecular docking and experimental validation were performed to confirm the binding between the key genes and colchicine. Lentiviral intervention and biochemical indicator detection were conducted to assess the impact of key genes on gout mice. Additionally, the therapeutic effect of colchicine incorporated into neutrophil membrane-coated nanoparticles was investigated. The study found that macrophage polarization plays a critical role in gout, and AHNAK was identified as the key gene through which colchicine affects macrophage polarization. Lentiviral intervention to decrease AHNAK expression was shown to alleviate joint swelling in gout mice and regulate macrophage polarization. Colchicine encapsulated in R4F peptide-modified neutrophil membrane-coated Pluronic F127 nanoparticle (R4F-NM@F127) nanocarriers inhibited M1 macrophage polarization, induced M2 macrophage polarization, alleviated gout, and minimized toxicity to normal tissues. Colchicine suppressed M1 macrophage polarization and induced M2 macrophage polarization by binding to AHNAK protein, thereby alleviating gout. Colchicine incorporated into R4F-NM@F127 nanocarriers can serve as a targeted therapeutic drug to regulate macrophage polarization, alleviate gout, and reduce toxicity to normal tissues.
Impact of Low-grade Intraepithelial Lesions with High-risk Human Papillomavirus (Part I)
Authors: Díaz López Elsa , Guarneros Gabriela , Mejía Morales Diana , Pérez-Prina Juan Cristóbal Conde , Elizalde Torres Indra , González Díaz Alberto
Published: October 2024

One of the cervical cancer screening tests that has been prevalent in low- and mid-level income countries has been the cytology test, which uses a system of standardized reports such as the Bethesda. This system allows the detection of anomalies in squamous epithelial cells, including the squamous intraepithelial lesion (SIL), low-grade squamous intraepithelial lesion (LSIL), high-grade squamous intraepithelial lesion (HSIL), invasive squamous cell carcinoma, and adenocarcinoma. This categorization in two levels (LSIL and HSIL) has allowed to differentiate the carcinogenic potential of the human papillomavirus (HPV). LSIL are described as transient changes associated with an infection caused by HPV and asymptomatic infections with viral vacuolization within a two-year interval with no specific treatment. In case of HSIL, reference is made to its pre-cancer potential. Several factors have an impact in the onset of a LSIL: the presence of HPV (as one of the key etiologic agents) and other risk factors such as hormones, microbiome, first intercourse at early age, multiple sexual partners, other infections, immune status, and tobaco. All that contribute to the transient nature of the infection, or to its persistence, which in turn may promote the development and progression into an HSIL. The persistence of a high-risk HPV infection (HR-HPV) (or more rarely of low-grade too) plays an important role in the development of cervical cancer.
Determining the Level of Emotional Intelligence of Future Cynologists
Authors: Bilotserkovets Marina , Fomenko Tetiana , Pavlenko Yuliia
Published: October 2024

The purpose of the paper is to investigate the essence of emotional intelligence (EI) as an important component for future cynologists’ fruitful work in the sphere of rehabilitation of people who have been affected by the war consiquences. The authors studied the scientific literature on EI and its role in “Human-Human” and “Human-Animal” interactions in the working sphere. The authors determined the existing EI level of students who have Cynology as their major, outlined the theoretic and empiric outcomes, and stated recommendations for improving future cynologists’ professional training.
Methodology. The empirical survey had a sample of 36 respondents. They were second-year students aged 18-21, 20 were male, and 16 were female. It was conducted by means of Google Forms on the basis of “Methodology of emotional intelligence diagnosis” by N. Hall (adapted) with subsequent processing and analysis of the results.
Results. The study of the literature revealed that EI is of crucial importance for future cynologists’ professional fulfillment as it is responsible for the emotional regulation of their behavior, self-motivation, empathy, etc. However, empirically, it was found out that the EI of the respondents had not been sufficiently developed, as 68% of the respondents had a low level of EI integrative index, 22% of the students had the medium level of EI integrative index. Solely 10% of the respondents were recorded to have a high-level EI integrative index.
Conclusions. The outcomes of the study revealed that most respondents do not have sufficient EI development, but they have the potential to enhance it. The authors insist on the organization of special educational courses and training to develop the ability of future cynologists to understand their own emotions and the emotions of other people, emotional behavior management, self-motivation, etc.