bluuebunny/crossref_metadata_2025 huggingface dataset:
THE EFFECTS OF ENVIRONMENTAL REGULATION ON EXPORTERS’ EXITING BEHAVIOR: THE EVIDENCE FROM CHINA
Authors: TU DONGMEI , LI YAO , ZENG YONG
Published: November 2017

This study investigates the impact of stricter environmental regulation on export exit behavior of Chinese manufacturing firms from 1998 to 2009. After controlling heterogeneous firm, we find that (i) on average, the stricter regulation has not significantly caused more export exit; (ii) under stricter policy, foreign invested pure (or pollution intensive) exporters are not more likely to exit export than domestic pure (or pollution intensive) exporters; (iii) only weak evidence supports the pollution haven hypothesis for domestic pure exporters. All our robustness checks such as difference in difference analysis, different regulation measurement, and matched firm analysis show similar results.
PEACE AND TOURISM: A NEXUS? EVIDENCE FROM DEVELOPED AND DEVELOPING COUNTRIES
Authors: KOLLIAS CHRISTOS , PAPADAMOU STEPHANOS
Published: November 2017

The paper empirically examines the nexus between tourism and peace. To do so, it uses in the analysis the recently developed composite Global Peace Index. The sample employed consists of 113 countries and covers the period 2008–2014. The methodology adopted includes PVAR Granger causality tests and impulse response functions. The sample was split into two income groups to allow for the possibility that the nexus differs between developed and developing countries. Findings reported herein indicate a temporary, very short-term adverse effect on tourism as a result of worsening levels of peacefulness only for the former group of countries. A peace promoting effect by tourism is established in the case of the latter group.
0∘ to 90∘ arbitrary controllable optical activity with an array of L-shaped silver holes inside a silica cube
Authors: Wang Wenbo , Hu Xiaobin , Wei Xin
Published: November 2017

We realize high efficiency 0–90[Formula: see text] arbitrary polarization rotation by using a single layer of L-shaped silver hole array inside a silica cube. The simulation results show that the 0–90[Formula: see text] arbitrary polarization rotation can be manipulated easily by adjusting the arm length of L-shaped holes, and the degree of linear polarization (DoLP) of the transmission spectra can achieve high over all range of 0–90[Formula: see text]. Our design has been optimized for 1550 nm wavelength. This arbitrary polarization rotation plasmonic metamaterial may provide more possibilities for applications in photonics.
A Dual Band Fractional-N Frequency Synthesizer with a Self-Calibrated Charge Pump for WLAN Standards
Authors: Azadbakht Mostafa , Sahafi Ali , Aghdam Esmaeil Najafi
Published: November 2017

This work presents a fully integrated fractional-[Formula: see text] frequency synthesizer that covers the entire frequency bands specified in the IEEE 802.11 a/b/g/n. In this paper, the effects of charge pump (CP) gain mismatch on spectral purity of local oscillator signal is studied theoretically and a new high precision self-calibrated CP is presented for alleviating the nonidealities. The idea is implemented in a 0.18-[Formula: see text]m standard CMOS technology. According to post layout simulation, the proposed calibration circuit demonstrates an excellent matching in the CP currents in a wide voltage range. By using this technique, the average of close-in phase noise of the designed frequency synthesizer is suppressed by more than 12[Formula: see text]dBc. The active whole chip die area is 0.475[Formula: see text]mm2 and the power dissipation from a 1.8-V DC supply is 17.3–20.6[Formula: see text]mW.
Low Latency Area-Efficient Distributed Arithmetic Based Multi-Rate Filter Architecture for SDR Receivers
Authors: Agarwal Ashok , Bopanna Lakshmi
Published: November 2017

In software defined radio (SDR) receivers, sample rate conversion (SRC) and channelization are two computational intensive tasks. Coefficient-less cascaded-integrator-comb (CIC) filters achieve SRC with low computational complexity, but the design of its gain droop compensation filter involves coefficients. These coefficients vary with the change in radio standards. In this paper, an architecture for variable digital filter (VDF) for gain droop compensation employing a set of fixed coefficient sub-filters and multi-dimensional polynomials in terms of spectral parameters is realized based on distributed arithmetic (DA). As the coefficients in the sub-filters are fixed, the proposed method uses ROM-based LUTs giving rise to low computational complexity. The proposed DA–VDF filter is synthesized on an application specific integrated circuit (ASIC) employing CMOS 90[Formula: see text]nm technology using Synopsis Design Complier. The proposed architecture achieves low latency at a reduced area delay product (ADP) of 78% and an efficiency of 72% in energy per sample (EPS) when compared with the conventional MAC-based architecture.
Restricting glycolysis impairs brown adipocyte glucose and oxygen consumption
Authors: Winther Sally , Isidor Marie S. , Basse Astrid L. , Skjoldborg Nina , Cheung Amanda , Quistorff Bjørn , Hansen Jacob B.
Published: November 2017

During thermogenic activation, brown adipocytes take up large amounts of glucose. In addition, cold stimulation leads to an upregulation of glycolytic enzymes. Here we have investigated the importance of glycolysis for brown adipocyte glucose consumption and thermogenesis. Using siRNA-mediated knockdown in mature adipocytes, we explored the effect of glucose transporters and glycolytic enzymes on brown adipocyte functions such as consumption of glucose and oxygen. Basal oxygen consumption in brown adipocytes was equally dependent on glucose and fatty acid oxidation, whereas isoproterenol (ISO)-stimulated respiration was fueled mainly by fatty acids, with a significant contribution from glucose oxidation. Knockdown of glucose transporters in brown adipocytes not only impaired ISO-stimulated glycolytic flux but also oxygen consumption. Diminishing glycolytic flux by knockdown of the first and final enzyme of glycolysis, i.e., hexokinase 2 (HK2) and pyruvate kinase M (PKM), respectively, decreased glucose uptake and ISO-stimulated oxygen consumption. HK2 knockdown had a more severe effect, which, in contrast to PKM knockdown, could not be rescued by supplementation with pyruvate. Hence, brown adipocytes rely on glucose consumption and glycolytic flux to achieve maximum thermogenic output, with glycolysis likely supporting thermogenesis not only by pyruvate formation but also by supplying intermediates for efferent metabolic pathways.
Granulosis Rubra Nasi Response to Topical Tacrolimus
Authors: Taj Farhana Tahseen , Vupperla Divya , Desai Prarthana B.
Published: November 2017

Granulosis Rubra Nasi (GRN) is a rare disorder of the eccrine glands. It is clinically characterized by hyperhidrosis of the central part of the face, most commonly on the tip of the nose, followed by appearance of diffuse erythema over the nose, cheeks, chin, and upper lip. It is commonly seen in childhood but it can present in adults. Here we report a case of GRN in an adult patient with very unusual histopathological presentation.
Mechanical Characterisation and Biomechanical and Biological Behaviours of Ti-Zr Binary-Alloy Dental Implants
Authors: Brizuela-Velasco Aritza , Pérez-Pevida Esteban , Jiménez-Garrudo Antonio , Gil-Mur Francisco Javier , Manero José María , Punset-Fuste Miquel , Chávarri-Prado David , Diéguez-Pereira Markel , Monticelli Francesca
Published: November 2017

The objective of the study is to characterise the mechanical properties of Ti-15Zr binary alloy dental implants and to describe their biomechanical behaviour as well as their osseointegration capacity compared with the conventional Ti-6Al-4V (TAV) alloy implants. The mechanical properties of Ti-15Zr binary alloy were characterised using Roxolid© implants (Straumann, Basel, Switzerland) via ultrasound. Their biomechanical behaviour was described via finite element analysis. Their osseointegration capacity was compared via an in vivo study performed on 12 adult rabbits. Young’s modulus of the Roxolid© implant was around 103 GPa, and the Poisson coefficient was around 0.33. There were no significant differences in terms of Von Mises stress values at the implant and bone level between both alloys. Regarding deformation, the highest value was observed for Ti-15Zr implant, and the lowest value was observed for the cortical bone surrounding TAV implant, with no deformation differences at the bone level between both alloys. Histological analysis of the implants inserted in rabbits demonstrated higher BIC percentage for Ti-15Zr implants at 3 and 6 weeks. Ti-15Zr alloy showed elastic properties and biomechanical behaviours similar to TAV alloy, although Ti-15Zr implant had a greater BIC percentage after 3 and 6 weeks of osseointegration.
ST Segment Elevation Is Not Always Myocardial Infarction: A Case of Focal Myopericarditis
Authors: Munguti Cyrus M. , Akidiva Samuel , Wallace Jacob , Farhoud Hussam
Published: November 2017

Protocols exist on how to manage STEMI patients, with well-established timelines. There are times when patients present with chest pain, ST segment elevation, and biomarker elevation that are not due to coronary artery disease. These conditions usually present with normal coronary angiography. We present a case that was clinically indistinguishable from STEMI and that was diagnosed with focal myopericarditis on cardiac MRI.
Workplace Phobic Anxiety as a Mental Health Phenomenon in the Job Demands-Resources Model
Authors: Vignoli Michela , Muschalla Beate , Mariani Marco Giovanni
Published: November 2017

Purpose. Anxiety-related problems at work are a serious problem in the occupational context, as they come along with sick leave and problems in work participation. The aim of this study is to analyse workplace phobic anxiety in nonclinical context using the Job Demands-Resources model. Methods. The study involved a sample of 739 workers from a retail company, mostly with permanent contracts. Structural equation modelling analyses were performed using AMOS software. Results. Both the health impairment and motivational variables in the JD-R model were significantly related to workplace phobic anxiety and subsequently to absenteeism, specifically, exhaustion mediated between perceived job demands and workplace phobic anxiety and work engagement mediated between perceived job resources and workplace phobic anxiety. Moreover, workplace phobic anxiety was significantly positively related to absenteeism. Conclusions. Results suggest that workplace phobic anxiety is a specific concept and an important issue in organizations for both workers’ health and the organizational costs linked to absenteeism. Supervisors and occupational physicians should be aware of workplace phobic anxiety, especially when workers are on sick leave often or for long periods.
Resveratrol Inhibits Propagation ofChlamydia trachomatisin McCoy Cells
Authors: Petyaev Ivan M. , Zigangirova Nayilia A. , Morgunova Elena Y. , Kyle Nigel H. , Fedina Elena D. , Bashmakov Yuriy K.
Published: November 2017

Resveratrol (RESV), an antifungal compound from grapes and other plants, has a distinct ability to inhibit theChlamydia (C.) trachomatisdevelopmental cycle in McCoy cells, a classic cell line used for chlamydial research. Inoculation ofC. trachomatiswith increasing amounts of RESV (from 12.5 to 100 μM) gave a dose-dependent reduction in the number of infected McCoy cells visualized by using monoclonal antibodies against chlamydial lipopolysaccharide. A similar trend has been observed with immunoassay for major outer membrane protein (MOMP). Furthermore, there was a step-wise reduction in the number ofC. trachomatisinfective progenies caused by the increasing concentrations of RESV. The ability of RESV to arrestC. trachomatisgrowth in McCoy cells was confirmed by a nucleic acid amplification protocol which revealed dose-dependent changes in mRNAs for different genes of chlamydial developmental cycle (euo,incA, andomcB). Although the precise nature of the antichlamydial activity of RESV is yet to be determined and evaluated in future studies, the observed effect of RESV onC. trachomatisinfection was not related to its potential effect on attachment/entry of the pathogen into eukaryotic cells or RESV toxicity to McCoy cells. Similar inhibitory effect was shown forC. pneumoniaeandC. muridarum.
Abdominal Pregnancy in the Small Intestine Presenting as Acute Massive Lower Gastrointestinal Hemorrhage
Authors: Pichaichanlert Apiradee , Luvira Vor , Tipsunthonsak Nakhon
Published: November 2017

An abdominal pregnancy is an ectopic pregnancy in which the implantation site occurs in the abdominal cavity outside the female reproductive organs. There have been four reported cases that ruptured into the gastrointestinal tract and into the large intestine. We present the first case of an abdominal pregnancy rupturing into the small intestine with a good outcome.
Treatment of Atypical Ulnar Fractures Associated with Long-Term Bisphosphonate Therapy for Osteoporosis: Autogenous Bone Graft with Internal Fixation
Authors: Shimada Yohei , Ishikawa Tetsuhiro , Endo Jun , Katsuragi Jo , Kotani Toshiaki , Kiuchi Hitoshi , Kuniyoshi Kazuki , Ohtori Seiji
Published: November 2017

Long-term bisphosphonate use has been suggested to result in decreased bone remodelling and an increased risk of atypical fractures. Fractures of this nature commonly occur in the femur, and relatively few reports exist to show that they occur in other bones. Among eight previous reports of atypical ulnar fractures associated with bisphosphonate use, one report described nonunion in a patient who was treated with cast immobilization and another described ulna nonunion in one of three patients, all of whom were treated surgically with a locking plate. The remaining two surgical patients achieved bone union uneventfully following resection of the osteosclerotic lesion and iliac bone grafting before rigid fixation. We hypothesized that the discontinuation of bisphosphonate therapy, the use of teriparatide treatment, and low-intensity pulsed ultrasound (LIPUS) might have been associated with fracture healing.
Purple Urine Bag Syndrome: A Rare Spot Diagnosis
Authors: Kalsi Dilraj S. , Ward Joel , Lee Regent , Handa Ashok
Published: November 2017

Purple urine bag syndrome (PUBS) is a complication of urinary tract infections (UTIs) where catheter bags and tubing turn purple. It is alarming for patients, families, and clinicians; however, it is in itself a benign phenomenon. PUBS is the result of UTIs with specific bacteria that produce sulphatases and phosphatases which lead tryptophan metabolism to produce indigo (blue) and indirubin (red) pigments, a mixture of which becomes purple. Risk factors include female gender, immobility, constipation, chronic catheterisation, and renal disease. Management involves reassurance, antibiotics, and regular changing of catheters, although there are debates regarding how aggressively to treat and no official guidelines. Prognosis is good, but PUBS is associated with high morbidity and mortality due to the backgrounds of patients. Here, we review the literature available on PUBS, present a summary of case studies from the last five years, and propose the Oxford Urine Chart as a tool to aid such diagnoses.
LSR Antibody Therapy Inhibits Ovarian Epithelial Tumor Growth by Inhibiting Lipid Uptake
Authors: Hiramatsu Kosuke , Serada Satoshi , Enomoto Takayuki , Takahashi Yusuke , Nakagawa Satoshi , Nojima Satoshi , Morimoto Akiko , Matsuzaki Shinya , Yokoyama Takuhei , Takahashi Tsuyoshi , Fujimoto Minoru , Takemori Hiroshi , Ueda Yutaka , Yoshino Kiyoshi , Morii Eiichi , Kimura Tadashi , Naka Tetsuji
Published: November 2017

Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy, but it still lacks effective treatment options. In this study, we utilized proteomic technology to identify lipolysis-stimulated lipoprotein receptor (LSR) as a new tumor antigen of EOC. Immunohistochemical analysis of EOC tissues in conjunction with survival analysis of EOC patients showed that high expression of LSR is associated with poor prognosis. High LSR expression also occurred in tumor metastases including to the lymph node and omentum. To evaluate the possible benefits of blocking this antigen in EOC, we raised a new monoclonal antibody (mAb) to human LSR (hLSR). In mouse xenograft models of hLSR+ EOC (cell lines or patient-derived tumors), we found that administration of anti-hLSR mAb inhibited tumor growth in a manner independent of both antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity. Mechanistic investigations showed that hLSR expression increased incorporation of very-low-density lipoprotein (VLDL) into EOC cells and that anti-hLSR mAb inhibited lipid uptake in vitro and in vivo. Moreover, VLDL promoted cell proliferation in hLSR-positive EOC cells in vitro, and this effect was inhibited by anti-hLSR mAb. While the anti-hLSR mAb studied cross reacted with the mouse antigen, we observed no adverse effects on normal organs and lipid metabolism in murine hosts. Our findings suggest that hLSR plays a key functional role in EOC development and that this antigen can be therapeutically targeted by specific mAb to improve EOC treatment.

Significance: These findings offer preclinical evidence of the therapeutic efficacy of a novel targeted antibody therapy against deadly epithelial ovarian cancers. Cancer Res; 78(2); 516–27. ©2017 AACR.
Successful Treatment of Oral Lichen Planus with Direct-Acting Antiviral Agents after Liver Transplantation for Hepatitis C Virus-Associated Hepatocellular Carcinoma
Authors: Nagao Yumiko , Nakasone Kazunori , Maeshiro Tatsuji , Nishida Nao , Kimura Kanae , Kawahigashi Yuji , Tanaka Yasuhito , Sata Michio
Published: November 2017

Hepatitis C virus (HCV) infection is frequently associated with various extrahepatic manifestations, such as autoimmune features and immune complex deposit diseases. Oral lichen planus (OLP) is one such extrahepatic manifestation of HCV infection. Recently, direct-acting antivirals (DAA) have proved to be highly effective and safe for the eradication of HCV. Herein, we report a case of OLP accompanied by HCV-related hepatocellular carcinoma (HCC) that disappeared after liver transplantation and achievement of sustained virological response following interferon (IFN)-free treatment with ledipasvir (LDV) and sofosbuvir (SOF). The 50-year-old patient developed erosive OLP during IFN therapy, with hyperthyroidism at 53 years of age and HCC at 55 years. He received immunosuppressive drugs and IFN-free DAA treatment after liver transplantation at 60 years of age, which led to disappearance of the symptoms of OLP. The patient was treated safely and effectively with LDV/SOF, although it is not known whether the disappearance of OLP resulted from the eradication of HCV or the immunosuppressive therapy.
A Hepatitis C Virus-Associated Chronic Hepatitis Patient Developing Various Adverse Events Including Severe Gingivitis, Gingival Bleeding, and Inflammation of Genital Vulva during the Course of Antiviral Therapy with Elbasvir/Grazoprevir
Authors: Tarao Kazuo , Sato Akira
Published: November 2017

Oral direct-acting antivirals comprise the main therapy for hepatitis C virus (HCV)-associated liver disease in Japan. Daclatasvir/asunaprevir is the primary agent and sofosbuvir/ledipasvir is the secondary agent for HCV genotype 1b. Ombitasvir/paritaprevir/ritonavir was also recommended as a therapy for HCV genotype 1b. More recently, elbasvir (NS5A inhibitor)/grazoprevir (NS3/4A protease inhibitor) was also recommended as a potent therapy for HCV genotype 1b infection. This agent achieved an SVR12 as high as 96.5% for HCV virus-associated chronic hepatitis. We recently encountered a case treated with this agent and the female patient showed various adverse events, such as severe gingivitis, gingival bleeding, severe tonsillitis, inflammation of the genital vulva, and the sustained sensation of being hungry. In spite of the gingival bleeding, there was no depletion of the platelet count, nor elongation of the prothrombin time. She tolerated these adverse events and finally completed the therapy and achieved SVR12.
Thulium Vaporesection of the Prostate and Thulium Vapoenucleation of the Prostate: A Retrospective Bicentric Matched-Paired Comparison with 24-Month Follow-Up
Authors: Becker Benedikt , Buttice Salvatore , Magno Carlo , Gross Andreas J. , Netsch Christopher
Published: November 2017

Introduction: To evaluate the intermediate-term outcomes of thulium vapoenucleation of the prostate (ThuVEP) and thulium vaporesection of the prostate (ThuVaRP) in patients with benign prostate obstruction (BPO). Materials and Methods: A bicentric retrospective matched-paired comparison of patients treated by ThuVEP (n = 80) or ThuVaRP (n = 80) was performed. The patients were preoperatively assessed with International Prostate Symptom Score (IPSS), quality of life (QoL), post-void residual urine (PVR), maximum urinary flow rate (Qmax), prostatespecific antigen (PSA) and re-evaluated at 12- and 24-month follow-up. Results: Median prostate volume was 65 mL and not different between the groups. The immediate re-operation rate was significantly different between ThuVEP and ThuVaRP (5 vs. 0%, p ≤ 0.0434). IPSS, QoL, Qmax and PVR had improved significantly compared to preoperative assessment in both groups at 12- and 24-month follow-up (p ≤ 0.001). Median Qmax (18.2 vs. 21.0 mL/s) and PVR (29.4 vs. 0 mL) were significantly different between ThuVEP and ThuVaRP at 24-month follow-up (p ≤ 0.001), while IPSS and QoL showed no differences between the groups. However, the PSA reduction was significantly higher after ThuVEP compared to ThuVaRP (78.93 vs. 23.39%, p ≤ 0.006) at 24-month follow-up. Conclusions: ThuVEP and ThuVaRP are safe and efficacious procedures for patients with BPO. Although the peri-operative re-intervention rates were lower after ThuVaRP, the low PSA reduction rate after ThuVaRP at 24-month follow-up favours the ThuVEP procedure.
Dynamic Profiling of Insulin Secretion and ATP Generation in Isolated Human and Mouse Islets Reveals Differential Glucose Sensitivity
Authors: Pingitore Attilio , Ruz-Maldonado Inmaculada , Liu Bo , Huang  Guo Cai , Choudhary Pratik , Persaud Shanta J.
Published: November 2017

Background/Aims: Rodent islets are often used for basic science research but they do not always recapitulate signalling events in human islets. This study evaluated the glucose-dependent responses of human and mouse islets in terms of dynamic insulin secretion, metabolic coupling and the role of glucose transporters. Methods: Glucose-induced insulin secretion from isolated mouse and human islets was profiled by perifusion and islet ATP levels were measured by chemoluminescence assay. Glucose transporter expression was determined by qPCR and western blotting. Results: Human islets show a left-shifted glucose concentration-insulin secretion profile compared to mouse islets. These data are consistent with glucose transporter expression, with human islets expressing mainly GLUT1 and GLUT3, and GLUT2 being the predominant transporter in mouse islets. Using the GLUT1 inhibitor STF-31 we unveiled an important role for GLUT1 for differences in glucose-induced insulin secretion profiles observed between the two species. Conclusion: The high affinity of GLUT1/3 for glucose reflects the left-shifted glucose-induced insulin secretory response of human islets and the impairment of insulin secretion from human islets after STF-31 treatment indicates an important role for GLUT1 in human islet stimulus-secretion coupling. Our data provide further insight into key differences between insulin secretion regulation in mouse and human islets.
n-3 Polyunsaturated Fatty Acids and Cardiovascular Disease: Principles, Practices, Pitfalls, and Promises - A Contemporary Review
Authors: Kones Richard , Howell Scott , Rumana Umme
Published: November 2017

Amidst voluminous literature, inconsistencies and opposing results have confused rather than clarified cardiologists' ability to assess the potential benefits of n-3 polyunsaturated fatty acids (n-3 PUFA). In perspective, there are common themes that emerge from n-3 PUFA studies, even as imperfect as they may be. The approach taken was to identify and unite these themes into a manageable, cohesive, evidence-based, yet useful synthesis. In all reviews and meta-analyses, the selection of component studies and assumptions influences outcomes. This overarching principle must be combined with the totality of the data, particularly when evidence is incompletely understood and gaps in knowledge must be bridged. Both the older literature and the most recent rigorous meta-analyses indicate that n-3 PUFA are highly pleiotropic agents with many documented positive physiological effects. Concordance among preclinical, observational, randomized clinical trials and meta-analyses is impressive. These agents have modest, statistically significant benefits which accrue over time. Given their favorable safety profile, a risk reduction of about 10% justifies their potential use in cardiovascular disease.
EpiFloripa Aging cohort study: methods, operational aspects, and follow-up strategies
Authors: Schneider Ione Jayce Ceola , Confortin Susana Cararo , Bernardo Carla de Oliveira , Bolsoni Carolina Carvalho , Antes Danielle Ledur , Pereira Karine Gonçalves , Ono Lariane Mortean , Marques Larissa Pruner , Borges Lucélia Justino , Giehl Maruí Weber Corseuil , Krug Rodrigo de Rosso , Goes Vanessa Fernanda , Boing Alexandra Crispim , Boing Antônio Fernando , D’Orsi Eleonora
Published: November 2017

OBJECTIVE: To describe the sample plan, operational aspects, and strategies used in the 2009/2010 and 2013/2014 EpiFloripa Aging Study. METHODS: The EpiFloripa Aging is a population-based longitudinal study with 1,705 older adults (60 years or more) living in the municipality of Florianópolis, State of Santa Catarina, Brazil, in 2009/2010 (baseline). The research was conducted with a face-to-face interviews, organized into blocks of identification, socioeconomic, mental health, health and life habits, global functionality, falls, physical activity, morbidities, use of health services, use of medications, food, oral health, and violence, evaluated in the first (2009/2010) and in the second wave (2013/2014). Additionally, in the second wave, we investigated the issue of discrimination and quality of life. RESULTS: The response rate of the first wave was 89.2% (n = 1,705). The baseline sample, with predominance of women (63.9%), was similar to the 2010 Census regarding age for women and slightly different for younger men. In the second wave, 1,197 participants were interviewed (response rate of 70.3%). Follow-up losses were only observed for the variable age group (p = 0.003), and predominantly for those aged 80 years or more. Mortality data linkage and active search for participants were used as a follow-up strategies. CONCLUSIONS: This study used strategies that were able to help locate the participants and maintain adherence, which ensured a good response rate during investigations.
Stand By for Tape Back-Up
Authors: Sutherland Ross
Published: November 2017

Poet Ross Sutherland found an old VHS tape in his attic. On it: a couple of old movies, a quiz show, half a sitcom episode. Through years of study, he slowly reorganized the footage into the story of his life.
Collective behaviour of wild Asian elephants in risky situations: how do social groups cross roads?
Authors: Mizuno Kaori , Sharma Nachiketha , Idani Gen’ichi , Sukumar Raman
Published: November 2017

Among group-living animals, some members may derive benefit by following the decisions of other members. Free-ranging wild Asian elephants in Mudumalai National Park, southern India, must often cross roads and can be disturbed by vehicles. We assessed if measures of road and traffic characteristics serve as indicators of risk, and compared behaviours of different age classes during road-crossing events. More individuals displayed excitable behaviour on wider roads. A larger number of adults entered the road first, which is considered the most dangerous position, compared with immature elephants. Immature individuals tended to move ahead of others on the road, suggesting that it is more important for immature individuals to follow adults at the beginning of a crossing than to follow along for the entire crossing. These findings may suggest that less experienced group members derive benefit by following the decisions of experienced ones under risky situations.
Social Capital, Religious Social Capital and the Missing Element of Religious Ritual
Authors: Swart Ignatius
Published: November 2017

This article was written to contribute towards developing a suitable conceptual framework for meeting the overarching research aim of developing a more profound empirically informed interpretation of the manner and extent to which religious ritual could be valued as a source of social capital formation in the South African context. With this in mind, the article first explores the concept of social capital in the light of the threefold distinction between bonding, bridging and linking forms of social capital. Secondly, from the vantage point of such exploration the connection with religion is made more pointedly. By tapping into the more recently invented notion of religious social capital, the article shows how this concept is today used meaningfully to advance a twofold perspective: on religion as a special repository of social capital, but also on the limitations of religion and its institutions in meeting the social capital needs of communities and the wider society. Finally, from the viewpoint of eliciting important conceptual value from the notion of religious social capital, the case of religious ritual as a very necessary yet untapped element in the contemporary research focus on religion and social capital formation is presented. In particular, an argument about religious ritual as the consistently missing element in this research focus is put forward and given greater substance through the identification of two pointers from the literature that can be deemed useful in starting to address this lacuna.
A new species of Marsipococcus Cockerell & Bueker (Hemiptera: Coccomorpha: Coccidae) from Malaysia
Authors: ŁAGOWSKA BOZENA , MARTIN JON H. , HODGSON CHRIS J.
Published: November 2017

The adult female, first-instar nymph, second-instar male, third-instar female, pupa and adult male of a new species of Marsipococcus Cockerell & Bueker (Hemiptera: Coccomorpha: Coccidae) from Malaysia, M. ulubendulensis Łagowska & Martin sp. n., are described and illustrated, while the second-instar female is only described. Marsipococcus is rediagnosed and a key to the adult females of the four species now placed in this genus is included.
A new subspecies of Short-toed Snake-eagle from Wallacea determined from morphological and DNA comparison
Authors: NG NATHANIEL S.R. , CHRISTIDIS LES , OLSEN JERRY , NORMAN JANETTE , RHEINDT FRANK E.
Published: November 2017

The taxonomic status of the geographically isolated population of Short-toed Snake-eagle Circaetus gallicus on the Lesser Sundas (=Nusa Tenggara) has been controversial. In the past they have been regarded as either a migrant population or a recently arrived resident population. Here we obtained DNA sequences from the mitochondrial cytochrome-b gene and combined genetic data with assessments of published and novel morphological data to clarify the taxonomic status of the Lesser Sundas population of C. gallicus. The cytochrome-b distance between the Lesser Sundas and Palearctic populations of C. gallicus is consistent with subspecific differentiation, indicating a possible divergence during one of the most recent Pleistocene glaciations. Although some of the morphological distinctions show overlap, the new subspecies can generally be diagnosed from nominate C. gallicus gallicus by being smaller and paler, and exhibiting less spotting and barring. Unlike nominate populations from mainland Eurasia, the new subspecies seems to lack pronounced sexual dimorphism. We here describe this new subspecies to science and discuss its biology and conservation status.
Scaling effects in the manufacture and testing of grid-stiffened composite structures
Authors: Alantali A , Alia RA , Umer R , Cantwell WJ
Published: November 2017

Scaling effects in the manufacture and testing of glass fiber-reinforced epoxy grid-stiffened structures have been investigated in this study. Four nominally identical scaled sizes of mold have been manufactured, in which the length, width, height, and internal channel sizes were varied to achieve ¼, ½, ¾ and full-scale stiffened structures. The panels were manufactured on a glass mold using the vacuum-assisted resin transfer molding technique, enabling the flow front to be monitored throughout the filling process. Grid-stiffened beams were removed from the cured panels and tested in flexure on scaled bending fixtures. The vacuum-assisted resin transfer molding manufacturing study on the four scaled sizes indicated that resin infusion incurred more rapidly in the smallest mold, possibly due to difficulties in accurately cutting the glass fabric, which in turn reduced the effective areal density of the fabric, thereby modifying its effective permeability. The flow rates and velocities of the resin fronts in the larger mold sizes were similar, suggesting that an appropriately scaled mold can be used to successfully predict the infusion process in more representative structures. Flexural tests on the grid-stiffened samples highlighted a similar response in the three largest samples, with the smallest sample again offering a modified response. Similar failure mechanisms, including fracture of the grid structure, debonding at the skin-core interface, and flexural failure in the center of the sample, were observed in all of the samples.
Let's Get Involved! The Impact of Service Learning on Drinking Perceptions, Alcohol Use, and Protective Behaviors in College Students
Authors: Flynn Mark A. , Carter Elizabeth , Craig Clay
Published: November 2017

While there is mounting support for the efficacy of alcohol-based curriculum infusion (CI) programs, studies have yielded mixed results. Insufficient attention has been given to nuances in the types of CI. Using a two-group pretest–posttest quasi-experimental design, this study assessed two forms of CI, information-only (IO) and service learning (SL), on drinking perceptions, drinking behavior, and protective behaviors. When the entire sample was considered, CI significantly improved participants' drinking perceptions and behavior. SL was more effective than IO for one measure of drinking behavior and for protective behaviors. Interestingly, there was a greater decrease in men's drinking behavior and increase in women's protective behaviors in the SL group. This study may help guide health professionals, educators, and faculty members interested in developing alcohol-focused CI programs.
Public Transport Connectivity and Intercity Tourist Flows
Authors: Yang Yang , Li Dong , Li Xiang (Robert)
Published: November 2017

In this study, we investigate how dyadic air and rail transport connectivity affects domestic tourist flows among 343 Chinese cities. Using geo-tagged Sina Weibo data to track tourists during China’s National Day Golden Week in 2014, we estimate several gravity models with a negative binomial distribution. The estimation results suggest that air transport connectivity generally has a greater influence than rail transport on dyadic tourist flows, while connectivity provided by ordinary trains (compared to other rail types) is most important in the context of rail transport. Also, we find the effects of transport connectivity and intermodal transport competition to depend on the origin-to-destination distance. Different types of railway trains appear to have distinct effective distance ranges: the effect of high-speed rail trains is strongest at travel distances between 1,800 and 2,000 km, whereas bullet trains’ effect is strongest at distances between 400 and 600 km.
The Compensatory Effect of Text-to-Speech Technology on Reading Comprehension and Reading Rate in Swedish Schoolchildren With Reading Disability
Authors: Grunér Sofia , Östberg Per , Hedenius Martina
Published: November 2017

The purpose of this study was (i) to investigate if the compensatory effect of text-to-speech (TTS) technology on reading comprehension and reading rate in schoolchildren with reading disability is influenced by problems with inattention and hyperactivity and (ii) to examine whether a potentially moderating effect of such symptoms differ between grade groups. Participants ( N = 49) were randomized into one of the two experimental conditions: Group A listened to a text with TTS, and Group B read the text themselves. The conditions were then switched. Inattention and hyperactivity symptoms were assessed with the Strengths and Difficulties Questionnaire (SDQ). Statistical analyses were performed both on the whole group and within-grade groups (Grades 3–5 and 6–9). Using TTS technology had a positive effect on reading rate for both grade groups, and this effect was not influenced by attention-deficit/hyperactivity disorder (ADHD) symptoms. As for reading comprehension, the two groups differed both with respect to the amount of improvement seen in the TTS condition and with respect to the moderating effect of ADHD symptoms. Reading with TTS improved reading comprehension significantly in the younger group, whereas no effect on reading comprehension was found in the older group. A higher score on the SDQ ADHD Scale was associated with less improvement in reading comprehension in the younger group and with greater improvement in reading comprehension in the older group. The results indicate that symptoms of inattention and hyperactivity, as well as the child’s grade level, are factors that should be taken into account when planning and introducing TTS technology.
Retail Consulting Class: Experiential Learning Platform to Develop Future Retail Talents
Authors: Oh Hyunjoo , Polidan Mary
Published: November 2017

The retail industry is undergoing a significant transformation. Factors such as technological advancement and evolving consumer demands have forced companies to rethink their traditional approaches to retail. Retailers have since embraced data-driven strategies with real-time implementation to stay relevant in this complex, ever-changing industry. This shift has generated a new demand for retail talent. Data-driven companies require workers with demonstrated skills in data analytics, critical thinking, cross-functional teamwork, and communication/leadership. We propose that the experiential learning platform of a retail consulting class is the most effective learning environment for students to develop these skills in a real-world retail context. This article connects the skillsets demanded in the evolving retail landscape to the learning outcomes of a retail consulting course. We describe the structure, elements, and process of the class to allow for adoption and successful implementation by other educational institutions. Then, we illustrate the learning outcomes by highlighting student testimonials and skill evaluations.
Effect of shape memory alloy wires on high-velocity impact response of basalt fiber metal laminates
Authors: Eslami-Farsani Reza , Khazaie Masoud
Published: November 2017

Fiber metal laminates are commonly used materials in industrial applications due to low density and excellent mechanical properties such as impact resistance. In this study, the effect of shape memory alloy wires on the impact properties of fiber metal laminates is evaluated and discussed. The volume fraction of wires and the pre-strain of wires were selected as the variables of the experiments. The samples were fabricated using hand lay-up method and their behavior was evaluated under high-velocity impact test. Based on the results, a significant change in the amount of absorbed energy was obtained using embedded wires. However, with increasing the volume fraction of wires, the absorbed energy decreases due to the discontinuity in mechanical properties of the specimens. On the other hand, applying pre-strain leads to residual stresses in samples. The observed residual stress in specimens with four embedded wires and 2% pre-strain level shows the most absorbed energy.
Undergraduate Men’s Self-Reports of Sexual Assault and Perceptions of College Campus Acquaintance Rape
Authors: McDaniel M. Colleen , Rodriguez Dario N.
Published: November 2017

Acquaintance rape is distressingly common on college campuses. Differing models of the perpetration of sexual assault make diverging predictions regarding the degree to which individual differences may distinguish among such sexual offenders and nonoffenders. Much research investigating these issues has primarily sampled students from large, commuter colleges. Such data may not generalize to students in other university settings (e.g., private schools, students in university housing). The present study sought to examine the rate of self-reported sexual assault among college men at a private school at which most students live in university housing. Furthermore, we examined whether individual difference characteristics—namely, endorsement of masculine gender norms and endorsement of modern myths about sexual assault—predicted participants’ perceptions of acquaintance rape. A total of 219 college men completed a survey consisting of the Male Role Norm Inventory (MRNI), followed by the Acceptance of Modern Myths About Sexual Aggression (AMMSA) and the Sexual Experiences Survey (SES). They then read a hypothetical acquaintance rape scenario and provided several ratings regarding their attributions of blame. Approximately, 4.6% of men self-reported having committed sexual assault. A Bayesian analysis indicated that self-reported offenders did not score differently on MRNI and AMMSA than self-reported nonoffenders, nor did they view the hypothetical scenario differently. Overall, men who endorsed male role norms tended to accept modern myths about rape and tended to attribute more blame to the victim and less blame to the perpetrator in the acquaintance rape scenario. We discuss methodological difficulties in conducting this type of research and identify several directions for future research.
Implementation of a Cardiac Transitions of Care Pilot Program: A Prospective Study of Inpatient and Outpatient Clinical Pharmacy Services for Patients With Heart Failure Exacerbation or Acute Myocardial Infarction
Authors: Murphy Julie A. , Schroeder Michelle N. , Rarus Rachel E. , Yakubu Idris , McKee Sean O. P. , Martin Steven J.
Published: November 2017

Background:

Pharmacists may assist with reducing 30-day readmission rates for patients with heart failure (HF) exacerbation or acute myocardial infarction (AMI) by promoting medication adherence.

Objective:

To determine the change in 30-day readmission rates for patients with HF exacerbation or AMI after implementation of a “high-touch” standard of care.

Methods:

Patients admitted with HF exacerbation, non-ST-segment elevation AMI, or ST-segment elevation AMI from August 1, 2013, to June 30, 2015, were included in this prospective study. Patients were educated while in the inpatient setting and followed up in the outpatient setting through telephone contact and scheduling a medication therapy management (MTM) appointment with a pharmacist. Data were collected by pharmacy personnel involved in the implementation of the intervention.

Results:

Within the HF and AMI arms, 100 and 93 patients, respectively, were included in the study. The 30-day readmission rates were 24% and 17.2% for HF and AMI, respectively, which were not statistically significant when compared to historical institutional readmission rates prior to study initiation (18.2% for HF, P = .238; 11.4% for AMI, P = .252).

Conclusion:

A “high-touch” pharmacist-driven transitions of care program may affect 30-day readmission rates for patients with HF exacerbation or AMI; potential processes for initiating transitions of care programs are provided.
Early Conceptual Understanding of Cardinality Predicts Superior School-Entry Number-System Knowledge
Authors: Geary David C. , vanMarle Kristy , Chu Felicia W. , Rouder Jeffrey , Hoard Mary K. , Nugent Lara
Published: November 2017

We demonstrate a link between preschoolers’ quantitative competencies and their school-entry knowledge of the relations among numbers (number-system knowledge). The quantitative competencies of 141 children (69 boys) were assessed at the beginning of preschool and throughout the next 2 years of preschool, as was their mathematics and reading achievement at the end of kindergarten and their number-system knowledge at the beginning of first grade. A combination of Bayes analyses and standard regressions revealed that the age at which the children had the conceptual insight that number words represent specific quantities (cardinal value) was strongly related to their later number-system knowledge and was more consistently related to broader mathematics than to reading achievement, controlling for intelligence, executive function, and parental education levels. The key implication is that it is not simply knowledge of cardinal value but the age of acquisition of this principle that is central to later mathematical development and school readiness.
Role of metformin on base excision repair pathway in p53 wild-type H2009 and HepG2 cancer cells
Authors: Dogan Turacli Irem , Candar Tuba , Yuksel Berrin Emine , Demirtas Selda
Published: November 2017

The antidiabetic agent metformin was shown to further possess chemopreventive and chemotherapeutic effects against cancer. Despite the advances, the underlying molecular mechanisms involved in decreasing tumor formation are still unclear. The understanding of the participation of oxidative stress in the action mechanism of metformin and its related effects on p53 and on DNA base excision repair (BER) system can help us to get closer to solve metformin puzzle in cancer. We investigated the effects of metformin in HepG2 and H2009 cells, verifying cytotoxicity, oxidative stress, antioxidant status, and DNA BER system. Our results showed metformin induced oxidative stress and reduced antioxidant capacity. Also, metformin treatment with hydrogen peroxide (H2O2) enhanced these effects. Although DNA BER enzyme activities were not changed accordantly together by metformin as a single agent or in combination with H2O2, activated p53 was decreased with increased oxidative stress in H2009 cells. Our study on the relationship between metformin/reactive oxygen species and DNA BER system in cancer cells would be helpful to understand the anticancer effects of metformin through cellular signal transduction pathways. These findings can be a model of the changes on oxidative stress that reflects p53’s regulatory role on DNA repair systems in cancer for the future studies.
A new electroactive polymer based on carbon nanotubes and carbon grease as compliant electrodes for electroactive actuators
Authors: Nicolau-Kuklińska Agata , Latko-Durałek Paulina , Nakonieczna Paulina , Dydek Kamil , Boczkowska Anna , Grygorczuk Jerzy
Published: November 2017

In this article, the novel type of dielectric elastomer made of polydimethylsiloxane, multi-walled carbon nanotubes, and carbon grease is presented. The aim of the study was the development of compliant electrodes with ability for large deformation under applied voltage. The largest deformation of 47% was obtained for electrodes made of 2 wt% of multi-walled carbon nanotubes and 20 wt% of carbon grease. Electrical conductivity achieved for this material was 4.8 S/m. Good dispersion of conductive fillers within silicone matrix was obtained by calendaring technique. It was found that electrical percolation threshold for the compound was below 0.05 wt%. The structure of the material and its mechanical properties were determined. It was described that both properties, electrical conductivity and stiffness of the nanocomposite, have a significant influence on the extent of the electrode deformation. Two actuator designs are presented as the examples of application of developed material.