bluuebunny/crossref_metadata_2025 huggingface dataset:
The relationship between personality and the response to acute psychological stress
Authors: Xin Yuanyuan , Wu Jianhui , Yao Zhuxi , Guan Qing , Aleman André , Luo Yuejia
Published: November 2017

The present study examined the relationship between personality traits and the response to acute psychological stress induced by a standardized laboratory stress induction procedure (the Trier Social Stress Test, TSST). The stress response was measured with a combination of cardiovascular reactivity, hypothalamic–pituitary–adrenal axis reactivity, and subjective affect (including positive affect, negative affect and subjective controllability) in healthy individuals. The Generalized Estimating Equations (GEE) approach was applied to account for the relationship between personality traits and stress responses. Results suggested that higher neuroticism predicted lower heart rate stress reactivity, lower cortisol stress response, more decline of positive affect and lower subjective controllability. Individuals higher in extraversion showed smaller cortisol activation to stress and less increase of negative affect. In addition, higher openness score was associated with lower cortisol stress response. These findings elucidate that neuroticism, extraversion and openness are important variables associated with the stress response and different dimensions of personality trait are associated with different aspects of the stress response.
Asymmetric adiabatic couplers for fully-integrated broadband quantum-polarization state preparation
Authors: Chung Hung-Pin , Huang Kuang-Hsu , Wang Kai , Yang Sung-Lin , Yang Shih-Yuan , Sung Chun-I , Solntsev Alexander S. , Sukhorukov Andrey A. , Neshev Dragomir N. , Chen Yen-Hung
Published: November 2017

Spontaneous parametric down-conversion (SPDC) is a widely used method to generate entangled photons, enabling a range of applications from secure communication to tests of quantum physics. Integrating SPDC on a chip provides interferometric stability, allows to reduce a physical footprint, and opens a pathway to true scalability. However, dealing with different photon polarizations and wavelengths on a chip presents a number of challenging problems. In this work, we demonstrate an on-chip polarization beam-splitter based on z-cut titanium-diffused lithium niobate asymmetric adiabatic couplers (AAC) designed for integration with a type-II SPDC source. Our experimental measurements reveal unique polarization beam-splitting regime with the ability to tune the splitting ratios based on wavelength. In particular, we measured a splitting ratio of 17 dB over broadband regions (>60 nm) for both H- and V-polarized lights and a specific 50%/50% splitting ratio for a cross-polarized photon pair from the AAC. The results show that such a system can be used for preparing different quantum polarization-path states that are controllable by changing the phase-matching conditions in the SPDC over a broad band. Furthermore, we propose a fully integrated electro-optically tunable type-II SPDC polarization-path-entangled state preparation circuit on a single lithium niobate photonic chip.
Uncovering the Pharmacological Mechanism of Astragalus Salvia Compound on Pregnancy-Induced Hypertension Syndrome by a Network Pharmacology Approach
Authors: Zeng Liuting , Yang Kailin , Ge Jinwen
Published: November 2017

To uncover the pharmacological mechanism of Astragalus Salvia compound (ASC) on pregnancy-induced hypertension syndrome (PIH), to provide useful information for clinical, as well as to connect the basic and clinical by a network pharmacological approach, we used network pharmacological approach. We collected ASC’s compounds by traditional Chinese Medicine databases, and input them into PharmMapper to got their targets. Then we acquired PIH targets from Genecards and OMIM, collected the interactions of all the targets and other human proteins via String and INACT. We also constructed the network by Cytoscape and analyze it by MCODE so as to get clusters. Finally, we put all the targets of clusters into DAVID to do GO enrichment analysis. After these, four networks are constructed by Cytoscape; they are PIH network, compound-compound target network of ASC, ASC-PIH network, and compound target-PIH target-other human proteins’ PPI network. According to the results, we think that ASC may directly regulate several biological processes and their genes in “endothelial cell activation and injury” and “placental or trophoblast cell ischemia” models to treat PIH. And it may indirectly act on the rest of the biological process to treat PIH or may not.
Identification of early ammonium nitrate-responsive genes in rice roots
Authors: Yang Hsiu-Chun , Kan Chia-Cheng , Hung Tzu-Huan , Hsieh Ping-Han , Wang Shi-Yun , Hsieh Wei-Yu , Hsieh Ming-Hsiun
Published: November 2017

Ammonium has long been used as the predominant form of nitrogen source for paddy rice (Oryza sativa). Recently, increasing evidence suggests that nitrate also plays an important role for nitrogen acquisition in the rhizosphere of waterlogged paddy rice. Ammonium and nitrate have a synergistic effect on promoting rice growth. However, the molecular responses induced by simultaneous treatment with ammonium and nitrate have been less studied in rice. Here, we performed transcriptome analysis to identify genes that are rapidly regulated by ammonium nitrate (1.43 mM, 30 min) in rice roots. The combination of ammonium and nitrate preferentially induced the expression of nitrate-responsive genes. Gene ontology enrichment analysis revealed that the early ammonium nitrate-responsive genes were enriched in “regulation of transcription, DNA-dependent” and “protein amino acid phosphorylation” indicating that some of the genes identified in this study may play an important role in nitrogen sensing and signaling. Several defense/stress-responsive genes, including some encoding transcription factors and mitogen-activated protein kinase kinase kinases, were also rapidly induced by ammonium nitrate. These results suggest that nitrogen metabolism, signaling, and defense/stress responses are interconnected. Some of the genes identified here may be involved in the interaction of nitrogen signaling and defense/stress-response pathways in plants.
Relevance of MIC-1 in the Era of PSA as a Serum Based Predictor of Prostate Cancer: A Critical Evaluation
Authors: Bansal Navneeta , Kumar Deepak , Gupta Ashish , Chandra Deepak , Sankhwar Satya Narain , Mandhani Anil
Published: November 2017

To reduce the ambiguity of contradictory observations in different studies regarding the expression level of Macrophage Inhibitory Cytokine-1 (MIC-1) in serum in prostate cancer (PC), benign prostatic hyperplasia (BPH) and healthy controls (HC), we designed this double-blind study. The study comprises 240 sera from PC, BPH and HC subjects. The expression level of MIC-1 in PC, BPH and HC were appraised using Western blot (WB) and ELISA based approach. WB and ELISA appraisal reveals that the expression level of MIC-1 is significantly higher in PC than in HC or BPH subjects. Regression analysis revealed a significant correlation between MIC-1 vs. PSA (r = 0.09; p < 0.001) and MIC-1 vs. GS (r = 0.7; p < 0.001). ROC analysis using discriminant predicted probability revealed that the MIC-1 was better than PSA. Moreover, the combination of MIC-1 and PSA was allowing 99.1% AUC for the differentiation of BPH + PC from HC, 97.9% AUC for differentiation of BPH from HC, 98.6% AUC for differentiation of PC from HC, and 96.7% AUC for the differentiation of PC from BPH. The augmented expression of MIC-1 in PC compared to BPH and HC subjects is in concurrent of the over-expression of MIC-1 in PC reports and confiscates the contradictory findings of other studies.
Formation of carbyne-like materials during low temperature pyrolysis of lignocellulosic biomass: A natural resource of linear sp carbons
Authors: Khanna Rita , Ikram-Ul-Haq Muhammad , Rawal Aditya , Rajarao Ravindra , Sahajwalla Veena , Cayumil Romina , Mukherjee Partha S.
Published: November 2017

The exploration, understanding and potential applications of ‘Carbyne’, the one-dimensional sp allotrope of carbon, have been severely limited due to its extreme reactivity and a tendency for highly exothermic cross-linking. Due to ill-defined materials, limited characterization and a lack of compelling definitive evidence, even the existence of linear carbons has been questioned. We report a first-ever investigation on the formation of carbyne-like materials during low temperature pyrolysis of biobased lignin, a natural bioresource. The presence of carbyne was confirmed by detecting acetylenic –C≡C– bonds in lignin chars using NMR, Raman and FTIR spectroscopies. The crystallographic structure of this phase was determined as hexagonal: a = 6.052 Å, c = 6.96 Å from x-ray diffraction results. HRSEM images on lignin chars showed that the carbyne phase was present as nanoscale flakes/fibers (~10 nm thick) dispersed in an organic matrix and showed no sign of overlapping or physical contact. These nanostructures did not show any tendency towards cross-linking, but preferred to branch out instead. Overcoming key issues/challenges associated with their formation and stability, this study presents a novel approach for producing a stable condensed phase of sp-bonded linear carbons from a low-cost, naturally abundant, and renewable bioresource.
Enteral Tube Feeding in Paediatric Mitochondrial Diseases
Authors: Choi Han Som , Lee Young-Mock
Published: November 2017

We investigated the effects of enteral tube feeding in Korean children with mitochondrial diseases. We performed a retrospective chart review of 68 paediatric patients with mitochondrial diseases on enteral tube feeding at a tertiary referral centre. The outcome of enteral nutrition was evaluated by decrease in gastrointestinal (GI) symptoms, weight gain, and increase in developmental quotient (DQ) among patients with data available. Among 68 patients, 56 (82%) were on gastrostomy and 12 (18%) were on prolonged nasogastric (NG) tube feeding. Decrease of GI symptoms was present in 37 of 48 patients (77%). Weight gain was present in 18 of 64 patients (28%) and was more prominent in the gastrostomy group (n = 17/54, 32%). Increase in DQ was similar between the NG tube and gastrostomy groups (total n = 10/48, 21%). Complications occurred in 42% (n = 5/12) of the NG tube group and 64% (n = 36/56) of the gastrostomy group. They varied in range, from mild to severe. Most complications were minor; there were 5 cases (9%) requiring gastrostomy removal or additional procedure and 2 cases (4%) of gastrostomy-related morbidity. Our results show that in paediatric patients with mitochondrial diseases, enteral tube feeding could help enhance quality of life by relieving GI symptoms, ameliorate growth failure and enhance development.
Adjuvant imatinib for patients with high-risk gastrointestinal stromal tumors: a retrospective cohort study
Authors: Zhao Rui , Wang Yong , Huang Yuqian , Cui Yaping , Xia Lin , Chen Yi , Zhuang Wen , Zhou Yong , Wu Xiaoting
Published: November 2017

The duration of adjuvant imatinib for high-risk patients with gastrointestinal stromal tumors (GISTs) is still controversial. Therefore, we retrospectively analyzed the data of high-risk patients with GISTs to investigate the appropriate duration. All 185 patients were divided into 4 groups: <1 year (Group A), 1–2 years (Group B), 2–3 years (Group C) and >3 years (Group D). The mean recurrence-free survival (RFS) in Groups A, B, and C were 44.3, 62.1, and 86.8 months, respectively (P < 0.001); the mean overall survival (OS) in Groups A, B and C was 75.2, 88.1, and 94.7 months, respectively (P = 0.009). The 5-year RFS in Groups A, B, C, and D was 15%, 26%, 83%, and 100%, respectively (P < 0.001); and the 5-year OS was 64%, 88%, 88%, and 100%, respectively (P < 0.001). The greatest impact on unfavorable outcomes was the tumor mitotic rate (HR, 2.01, 95% CI, 1.38–2.94; P < 0.001). Duration of adjuvant imatinib was the only favorable factor (HR, −0.95, 95% CI, 0.93–0.97; P < 0.001). For high-risk patients with high tumor size or mitotic rate, or non-gastric GISTs, we recommend that more than 3 years of adjuvant imatinib is feasible.
Cooling-rate induced softening in a colloidal glass
Authors: Lu Yunzhuo , Zhang Zhihua , Lu Xing , Qin Zuoxiang , Shen Jun , Huang Yongjiang , Liaw Peter K.
Published: November 2017

Contrary to crystalline solids, amorphous solids always become softer when vitrifying the melts under higher cooling rates. Understanding this phenomenon is of utmost importance in providing a basis for the mechanical-performance control of amorphous solids. However, the underlying mechanisms leading to this cooling-rate-induced softening of amorphous solids have remained elusive, especially the dynamic reasons are neglected. Here, we use a colloidal glass as the model system to directly study this issue. Shear modulus is used as the representative parameter to monitor the stress-bearing properties of colloidal glass. The space-spanning immobile particles, whose population is sensitive to the cooling rate, are found to make the dominant contribution to the shear modulus. The rapid solidification induced softening of colloidal glass is observed to originate from fewer immobile particles formed at higher cooling rates.
Open University Learning Analytics dataset
Authors: Kuzilek Jakub , Hlosta Martin , Zdrahal Zdenek
Published: November 2017

Learning Analytics focuses on the collection and analysis of learners’ data to improve their learning experience by providing informed guidance and to optimise learning materials. To support the research in this area we have developed a dataset, containing data from courses presented at the Open University (OU). What makes the dataset unique is the fact that it contains demographic data together with aggregated clickstream data of students’ interactions in the Virtual Learning Environment (VLE). This enables the analysis of student behaviour, represented by their actions. The dataset contains the information about 22 courses, 32,593 students, their assessment results, and logs of their interactions with the VLE represented by daily summaries of student clicks (10,655,280 entries). The dataset is freely available at https://analyse.kmi.open.ac.uk/open_dataset under a CC-BY 4.0 license.
Monitoring transcription initiation activities in rat and dog
Authors: Lizio Marina , Mukarram Abdul Kadir , Ohno Mizuho , Watanabe Shoko , Itoh Masayoshi , Hasegawa Akira , Lassmann Timo , Severin Jessica , Harshbarger Jayson , Abugessaisa Imad , Kasukawa Takeya , Hon Chung Chau , Carninci Piero , Hayashizaki Yoshihide , Forrest Alistair R.R. , Kawaji Hideya
Published: November 2017

The promoter landscape of several non-human model organisms is far from complete. As a part of FANTOM5 data collection, we generated 13 profiles of transcription initiation activities in dog and rat aortic smooth muscle cells, mesenchymal stem cells and hepatocytes by employing CAGE (Cap Analysis of Gene Expression) technology combined with single molecule sequencing. Our analyses show that the CAGE profiles recapitulate known transcription start sites (TSSs) consistently, in addition to uncover novel TSSs. Our dataset can be thus used with high confidence to support gene annotation in dog and rat species. We identified 28,497 and 23,147 CAGE peaks, or promoter regions, for rat and dog respectively, and associated them to known genes. This approach could be seen as a standard method for improvement of existing gene models, as well as discovery of novel genes. Given that the FANTOM5 data collection includes dog and rat matched cell types in human and mouse as well, this data would also be useful for cross-species studies.
RE-Europe, a large-scale dataset for modeling a highly renewable European electricity system
Authors: Jensen Tue V. , Pinson Pierre
Published: November 2017

Future highly renewable energy systems will couple to complex weather and climate dynamics. This coupling is generally not captured in detail by the open models developed in the power and energy system communities, where such open models exist. To enable modeling such a future energy system, we describe a dedicated large-scale dataset for a renewable electric power system. The dataset combines a transmission network model, as well as information for generation and demand. Generation includes conventional generators with their technical and economic characteristics, as well as weather-driven forecasts and corresponding realizations for renewable energy generation for a period of 3 years. These may be scaled according to the envisioned degrees of renewable penetration in a future European energy system. The spatial coverage, completeness and resolution of this dataset, open the door to the evaluation, scaling analysis and replicability check of a wealth of proposals in, e.g., market design, network actor coordination and forecasting of renewable power generation.
Sensing the impact of environment on small molecule differentiation of RNA sequences
Authors: Eubanks Christopher S. , Hargrove Amanda E.
Published: November 2017

Pattern recognition of RNA with small molecules (PRRSM) reveals the impact of environmental conditions on the differentiation of RNA structures.
Photoresponsive spherical nucleic acid: spatiotemporal control of the assembly circuit and intracellular microRNA release
Authors: Zhou Xiang , Li Hui , He Miao , Yin Xue , Yao Dongbao , Xiao Shiyan , Liang Haojun
Published: November 2017

A photoresponsive spherical nucleic acid (SNA) conjugate can achieve spatiotemporal regulation in a nanoassembly reaction and microRNA release, which overcomes the potential drawbacks of traditional SNA.
Rapid, enantioselective synthesis of the C1–C13 fragment of biselyngbyolide B
Authors: Thorat Rakesh G. , Harned Andrew M.
Published: November 2017

Using catalytic transformations for C–C bond formation allows for a nine-step synthesis of the biselyngbyolide C1–C13 fragment.
Versatile (η6-arene)Ni(PCy3) nickel monophosphine precursors
Authors: Zhu Sha , Shoshani Manar M. , Johnson Samuel A.
Published: November 2017

Revisiting the solution behaviour of [(PCy3)2Ni]2N2reveals a facile synthesis for the versatile Ni(PCy3) transfer reagents, (η6-arene)Ni(PCy3).
Molecular structure and hydrogen bond interactions of a paracetamol–4,4′-bipyridine cocrystal studied using a vibrational spectroscopic and quantum chemical approach
Authors: Srivastava Karnica , Khan Eram , Shimpi Manishkumar R. , Tandon Poonam , Sinha Kirti , Velaga Sitaram P.
Published: November 2017

Paracetamol–4,4′-bipyridine cocrystal studied using vibrational spectroscopic and quantum chemical approach.
Thermally reversible nanoparticle gels with tuneable porosity showing structural colour
Authors: Ruff Z. , Cloetens P. , O’Neill T. , Grey C. P. , Eiser E.
Published: November 2017

A novel functionalization-chemistry of silica-nanoparticles with either PEG or PEG + DNA leads to optically scattering colloidal gels.
Unimolecular decay strongly limits the atmospheric impact of Criegee intermediates
Authors: Vereecken L. , Novelli A. , Taraborrelli D.
Published: November 2017

The stabilized Criegee intermediates formed from large, biogenic VOC often have multiple unimolecular decay channels with high rate coefficients.
Well-ordered self-assembled nanostructures of block copolymer films via synergistic integration of chemoepitaxy and zone annealing
Authors: Zhang Liangshun , Liu Lingling , Lin Jiaping
Published: November 2017

The integrated chemical template/zone annealing method has the capability to rapidly fabricate well-aligned and well-oriented nanostructures over a macroscopic area.
In situsynthesis of magnesium hydroxides modified with tripodal ligands in an organic medium
Authors: Muramatsu Keisuke , Kuroda Yoshiyuki , Wada Hiroaki , Shimojima Atsushi , Kuroda Kazuyuki
Published: November 2017

The use of organic solvents enhanced the designability of the surface functional groups of interlayer-modified magnesium hydroxides with tripodal ligands.
Assembly of a series of coordination polymers built from rigid a tetracarboxylate ligand and flexible bis(imidazole) linker: syntheses, structural diversities, luminescence sensing, and photocatalytic properties
Authors: Zhang Xiu-Tang , Chen Hong-Tai , Li Bin , Liu Guang-Zeng , Liu Xin-Zheng
Published: November 2017

CPs have been constructed from the reaction of terphenyl-4,2′′,5′′,4′-tetracarboxylic acid and two different bis(imidazole) bridging linkers under hydrothermal conditions.
Open and closed forms of the interpenetrated [Cu2(Tae)(Bpa)2](NO3)2·nH2O: magnetic properties and high pressure CO2/CH4gas sorption
Authors: Fernández de Luis Roberto , Larrea Edurne S. , Orive Joseba , Fidalgo-Marijuan Arkaitz , Lezama Luis , Arriortua María I.
Published: November 2017

Cationic [Cu2(Tae)(Bpa)2]2+[NO3]22−·nH2O interpenetrated networks show a solvent loss triggering dynamic aperture of the porous structure from a closed to an open form with a difference of 29% of the volume cell.
Challenges in characterizing the environmental fate and effects of carbon nanotubes and inorganic nanomaterials in aquatic systems
Authors: Laux Peter , Riebeling Christian , Booth Andy M. , Brain Joseph D. , Brunner Josephine , Cerrillo Cristina , Creutzenberg Otto , Estrela-Lopis Irina , Gebel Thomas , Johanson Gunnar , Jungnickel Harald , Kock Heiko , Tentschert Jutta , Tlili Ahmed , Schäffer Andreas , Sips Adriënne J. A. M. , Yokel Robert A. , Luch Andreas
Published: November 2017

Characterization of carbon nanotube dispersions requires measurement of both, concentration and surface area.
Cell type specific cytoskeleton disruption induced by engineered nanoparticles
Authors: Ispanixtlahuatl-Meráz Octavio , Schins Roel P. F. , Chirino Yolanda I.
Published: November 2017

One of the main concerns regarding nanomaterials is the cytotoxicity caused by engineered nanoparticles (NPs) after inhalation, oral or dermal routes of exposure, intravenous application, and delivery as debris from implants.
Size- and surface charge-controlled layered double hydroxides for efficient algal flocculation
Authors: Kim Tae-Hyun , Hong In Taek , Oh Jae-Min
Published: November 2017

We evaluated the effects of particle size and surface charge on the algal flocculation activity of layered double hydroxides (LDHs).
Waste-minimised copper-catalysed azide–alkyne cycloaddition in Polarclean as a reusable and safe reaction medium
Authors: Luciani Lorenzo , Goff Emily , Lanari Daniela , Santoro Stefano , Vaccaro Luigi
Published: November 2017

Herein we report the first example of a generally useful organic reaction, namely the copper-catalysed azide–alkyne cycloaddition, performed in a Polarclean/water mixture as a reaction medium.
Rhodium-catalyzed intermolecular C(sp3)–H amination in a purely aqueous system
Authors: Lu Xunbo , Shi Yufeng , Zhong Fangrui
Published: November 2017

An efficient Rh-catalyzed intermolecular C(sp3)–H amination in a purely aqueous system is developed for the first time.
Brønsted acid-catalyzed metal- and solvent-free quinoline synthesis fromN-alkyl anilines and alkynes or alkenes
Authors: Ahmed Waqar , Zhang Sheng , Yu Xiaoqiang , Yamamoto Yoshinori , Bao Ming
Published: November 2017

A convenient and efficient method for quinoline synthesis was developed using simple and readily available starting materials under green conditions.
Translesion DNA synthesis across double-base lesions derived from cross-links of an antitumor trinuclear platinum compound: primer extension, conformational and thermodynamic studies
Authors: Novakova O. , Farrell N. P. , Brabec V.
Published: November 2017

The central linker of antitumor polynuclear Triplatin represents an important factor responsible for the lowered tolerance of its DNA double-base adducts by DNA polymerases.
Efficient coverage of ZnO nanoparticles on cotton fibres for antibacterial finishing using a rapid and low cost in situ synthesis
Authors: Borda d’ Água Raquel , Branquinho Rita , Duarte Maria Paula , Maurício Elisabete , Fernando Ana Luísa , Martins Rodrigo , Fortunato Elvira
Published: November 2017

Antibacterial fabric using a simple, reproducible and low cost technique to synthesize high-quality ZnONPs was prepared and characterized.
In situ ion exchange synthesis of MoS2/g-C3N4 heterojunctions for highly efficient hydrogen production
Authors: Wang Min , Ju Peng , Zhao Yun , Li Jiajia , Han Xiuxun , Hao Zhaomin
Published: November 2017

Tight nanojunctions between g-C3N4 and MoS2 were constructed, which facilitate the separation of photogenerated charge carriers.
Gold nanoparticle-based colorimetric biosensors
Authors: Aldewachi H. , Chalati T. , Woodroofe M. N. , Bricklebank N. , Sharrack B. , Gardiner P.
Published: November 2017

Gold nanoparticles (AuNPs) provide excellent platforms for the development of colorimetric biosensors as they can be easily functionalised, displaying different colours depending on their size, shape and state of aggregation.
Rh(iii)-Catalyzedortho-C–H alkynylation ofN-phenoxyacetamides with hypervalent iodine-alkyne reagents at room temperature
Authors: Hu Sisheng , Lu Liang , Zhu Tongyang , Wu Qian , Chen Ying , Li Jie Jack , Zhao Jing
Published: November 2017

Directing group ONHR preservedortho-alkynylation under mild conditions catalyzed by rhodium is reported.
Correction: Synthesis of well-defined α,ω-telechelic multiblock copolymers in aqueous medium: in situ generation of α,ω-diols
Authors: Simula Alexandre , Nikolaou Vasiliki , Anastasaki Athina , Alsubaie Fehaid , Nurumbetov Gabit , Wilson Paul , Kempe Kristian , Haddleton David M.
Published: November 2017

Correction for ‘Synthesis of well-defined α,ω-telechelic multiblock copolymers in aqueous medium: in situ generation of α,ω-diols’ by Alexandre Simula et al., Polym. Chem., 2015, 6, 2226–2233.
Correction: The effect of ligand, solvent and Cu(0) source on the efficient polymerization of polyether acrylates and methacrylates in aqueous and organic media
Authors: Simula Alexandre , Nikolaou Vasiliki , Alsubaie Fehaid , Anastasaki Athina , Haddleton David M.
Published: November 2017

Correction for ‘The effect of ligand, solvent and Cu(0) source on the efficient polymerization of polyether acrylates and methacrylates in aqueous and organic media’ by Alexandre Simula et al., Polym. Chem., 2015, 6, 5940–5950.
Fluorescence visualization of crystal formation and transformation processes of organic luminogens with crystallization-induced emission characteristics
Authors: Zheng Chao , Zang Qiguang , Nie Han , Huang Weitao , Zhao Zujin , Qin Anjun , Hu Rongrong , Tang Ben Zhong
Published: November 2017

A real-time, on-site, nondestructive, fluorescence imaging technique has been reported to monitor the crystal formation and transformation processes of organic luminogens.
Synergistic catalysis: enantioselective cyclopropanation of alkylidene benzoxazoles by Pd(ii) and secondary amine catalysis. Scope, limitations and mechanistic insight
Authors: Meazza Marta , Polo Victor , Merino Pedro , Rios Ramon
Published: November 2017

An enantioselective synergistic cascade cyclopropanation/NHC catalyzed ring opening has been reported. DFT calculations have been performed to confirm the mechanism.
Generation of sulfonated isobenzofuran-1(3H)-ones under photocatalysis through the insertion of sulfur dioxide
Authors: Zhang Jun , Zhou Kaida , Wu Jie
Published: November 2017

Generation of sulfonated isobenzofuran-1(3H)-ones starting from 2-vinylbenzoic acids, aryldiazonium tetrafluoroborates, and DABCO˙(SO2)2 under photocatalysis in the presence of visible light is achieved. Additionally, the method can be extended to 4-phenylpent-4-enoic acid and 5-phenylhex-5-enoic acid.
Nucleobase-modified antisense oligonucleotides containing 5-(phenyltriazol)-2′-deoxyuridine nucleotides induce exon-skipping in vitro
Authors: Le Bao T. , Hornum Mick , Sharma Pawan K. , Nielsen Poul , Veedu Rakesh N.
Published: November 2017

We investigated the potential of nucleobase-modified antisense oligonucleotides to induce exon-skipping, and found that 5-(phenyltriazol)-2′-deoxyuridine-modified antisense oligonucleotides induced efficient exon-skipping in vitro.
Investigation of Fe2+-incorporating organic–inorganic hybrid perovskites from first principles and experiments
Authors: Zhou Long , Chang Jingjing , Lin Zhenhua , Zhang Chunfu , Chen Dazheng , Zhang Jincheng , Hao Yue
Published: November 2017

The structural, electronic, magnetic and optical properties of the perovskite CH3NH3(Pb:Fe)I3have been systematically studied by using the first-principle calculation.
The mechanism of directed Ni(ii)-catalyzed C–H iodination with molecular iodine
Authors: Haines Brandon E. , Yu Jin-Quan , Musaev Djamaladdin G.
Published: November 2017

This computational study reveals electrophilic cleavage pathways for substrates with N,N-bidentate directing centers in Ni(ii)-catalyzed C–H iodination with molecular iodine.
A crystal engineering approach for scalable perovskite solar cells and module fabrication: a full out of glove box procedure
Authors: Yaghoobi Nia N. , Zendehdel M. , Cinà L. , Matteocci F. , Di Carlo A.
Published: November 2017

In the present work we used some crystallization trends which could be classified as a Crystal Engineering (CE) approach, for deposition of a pure cubic-phase thin film of CH3NH3PbI3 (MAPbI3) on the surface of a mesoporous TiO2 layer.
Tailoring the surface pore size of hollow fiber membranes in the TIPS process
Authors: Fang Chuanjie , Jeon Sungil , Rajabzadeh Saeid , Cheng Liang , Fang Lifeng , Matsuyama Hideto
Published: November 2017

A new method was used to tailor the surface pore size of PVDF hollow fiber membranes in the TIPS process by the co-extrusion of different solvents at the outer layer of the extruded polymeric solution.
Low thermal conductivity in La-filled cobalt antimonide skutterudites with an inhomogeneous filling factor prepared under high-pressure conditions
Authors: Serrano-Sánchez F. , Prado-Gonjal J. , Nemes N. M. , Biskup N. , Varela M. , Dura O. J. , Martínez J. L. , Fernández-Díaz M. T. , Fauth F. , Alonso J. A.
Published: November 2017

La-filled skutterudites with an inhomogeneous filling factor synthesized by high pressure exhibit a remarkably low lattice thermal conductivity.
Particle and nanofiber shaped conjugated microporous polymers bearing hydantoin-substitution with high antibacterial activity for water cleanness
Authors: Wang Fei , Ren Feng , Ma Dan , Mu Peng , Wei Huijuan , Xiao Chaohu , Zhu Zhaoqi , Sun Hanxue , Liang Weidong , Chen Jixiang , Chen Lihua , Li An
Published: November 2017

Efficient elimination of widespread microbial contamination in water is of great importance to address severe environmental issues.
A versatile platform to achieve mechanically robust mussel-inspired antifouling coatings via grafting-to approach
Authors: Mu Youbing , Wu Zelin , Pei Danfeng , Wang Jiming , Wan Xiaobo
Published: November 2017

A facile and efficient method to fabricate robust antifouling coatings via a grafting-to approach based on polyvinyl alcohol (PVA)-based biomimetic substrates is reported.
Valence band modification of Cr2O3by Ni-doping: creating a high figure of merit p-type TCO
Authors: Arca Elisabetta , Kehoe Aoife B. , Veal Tim D. , Shmeliov Aleksey , Scanlon David O. , Downing Clive , Daly Dermot , Mullarkey Daragh , Shvets Igor V. , Nicolosi Valeria , Watson Graeme W.
Published: November 2017

In Cr2O3, Ni is a more effective dopand than Mg due to its higher solubility and its capability to contribute to the VB, improving holes dispersion.
Degradation of encapsulated perovskite solar cells driven by deep trap states and interfacial deterioration
Authors: Khadka Dhruba B. , Shirai Yasuhiro , Yanagida Masatoshi , Miyano Kenjiro
Published: November 2017

The degradation of perovskite device performance is found to be driven by interfacial deterioration in the device and induced deep trap assisted recombination in the perovskite with aging.
Solution-processedN-trialkylated triindoles for organic field effect transistors
Authors: Ruiz C. , Arrechea-Marcos I. , Benito-Hernández A. , Gutierrez-Puebla E. , Monge M. A. , López Navarrete J. T. , Ruiz Delgado M. C. , Ortiz R. Ponce , Gómez-Lor Berta
Published: November 2017

Self-assembly ofN-alkyl triindoles driven by CH–π interactions gives rise to highly aligned films successfully incorporated into solution-processed OFETs.
A red thermally activated delayed fluorescence material as a triplet sensitizer for triplet–triplet annihilation up-conversion with high efficiency and low energy loss
Authors: Wei Danqing , Ni Fan , Zhu Zece , Zou Yang , Yang Chuluo
Published: November 2017

A red thermally activated delayed fluorecence molecule was employed to realize green-to-blue up-conversion emission with a large anti-Stokes shift and highΦUC′.
Silver nanoplate aggregation based multifunctional black metal absorbers for localization, photothermic harnessing enhancement and omnidirectional light antireflection
Authors: Zhang Xiao-Yang , Shan Feng , Zhou Huan-Li , Su Dan , Xue Xiao-Mei , Wu Jing-Yuan , Chen Yu-Zhang , Zhao Ning , Zhang Tong
Published: November 2017

A silver nanoplate aggregation based plasmonic absorber layer with excellent light confinement and photothermic harvesting performance in the broadband range.
Fast and precise solving of non‐linear optimisation problem for field calibration of triaxial accelerometer
Authors: Ranjbaran S. , Ebadollahi S.
Published: November 2017

Unlike laboratory calibration methods, filed calibration methods are not time consuming, costly and do not need laboratory equipment, so they can be used in any environment for calibration of low‐cost MEMS accelerometers. The magnitude of gravity vector in static state is used as a reference in the calibration process. Then a cost function is defined which is non‐linear and complex. So, in order to simplify this equation, a novel change of variables is proposed which converts this non‐linear optimisation problem to a linear least square (LLS) method and a non‐linear equation solving. After minimisation of this cost function using LLS method, bias, scale factor and non‐orthogonality of the accelerometer are estimated and it is compared with two other field calibration methods. The results of simulations show good performance of proposed method. For online estimation of these coefficients, recursive least squares method is also utilised. Finally, simulations in MATLAB have shown that they converge to the true values.
Linear inequalities convex transformation for optimal reactive power flow model based on MISOCP relaxations
Authors: Lin Chunmei , Wei Hua , Hou Wenting , Tan Jiancheng
Published: November 2017

A convex optimisation model for global optimum solution of optimal reactive power flow (ORPF) problem is proposed in this study, to solve the challenge of discrete variables of transformer taps involved in traditional ORPF models. Based on the second‐order cone programming relaxation, a set of inequalities with 0–1 variables are introduced, to convexify the non‐convex items that are products of discrete variables (or squares of discrete variables) and linear functions. After convexification, items containing second order of transformer ratio variables are dropped to the first order, and the non‐convex non‐linear nodal power equalities are equivalently transformed into linear equalities, thus formulating a mix‐integer second‐order cone programming (MISOCP) model of ORPF problem over feasible convex domain, which guarantees the global optimum theoretically. The results of IEEE‐14, 30, 57, 118 bus systems show that, with stable numerical property and good optimum effect, the proposed model can give consideration to not only the quality of solution, but also the efficiency of calculation.
Enhancing short‐term probabilistic residential load forecasting with quantile long–short‐term memory
Authors: Gan Dahua , Wang Yi , Zhang Ning , Zhu Wenjun
Published: November 2017

In the study of load forecasting, short‐term (ST) load forecasting in the horizon of individuals is prone to manifest non‐stationary and stochastic features compared with predicting the aggregated loads. Hence, better methodologies should be proposed to forecast ST residential loads more accurately, and refined representation of forecasting results should be reconsidered to make the prediction more reliable. A format of ST probabilistic forecasting results in terms of quantiles is offered, which can better describe the uncertainty of residential loads, and a deep‐learning‐based method, quantile long–ST memory, to implement probabilistic residential load forecasting. Experiments are conducted on an open dataset. Results show that the proposed method overrides traditional methods significantly in terms of average quantile score.
Power transformer fault diagnosis using FCM and improved PCA
Authors: Kari Tusongjiang , Gao Wensheng
Published: November 2017

In order to improve fault diagnosis accuracy of power transformer, a new fault diagnosis model based on fuzzy C‐means (FCM) clustering algorithm and improved principal component analysis (IPCA) is presented. First, dissolve gas analysis samples are clustered with FCM and cluster centre for each fault type is regarded as reference sequence. Then, the IPCA approach is implemented to obtain main principal components containing 95% of original information. Finally, Euclidean distances between principal components of reference sequence and testing sample are calculated to identify final fault type. Cases studies and test results show that the proposed approach achieves recognition of transformer fault effectively and has a higher diagnostic accuracy than the international electrotechnical commission (IEC) ratio method and the improved three ratio method.
An Efficient Cyanide-Free Approach towards 1-(2-Pyridyl)isoquinoline-3-carbonitriles via the Reaction of 5-Phenacyl-1,2,4-triazines with 1,2-Dehydrobenzene in the Presence of Alkyl Nitrites
Authors: Santra Sougata , Kopchuk Dmitry , Krinochkin Alexey , Khasanov Albert , Kovalev Igor , Slepukhin Pavel , Starnovskaya Ekaterina , Mukherjee Anindita , Rahman Matiur , Zyryanov Grigory , Majee Adinath , Rusinov Vladimir , Chupakhin Oleg
Published: November 2017

A cyanide-free method for the preparation of 1-(2-pyridyl)isoquinoline-3-carbonitriles (3-cyanoisoquinolines) was developed. The interaction of 5-phenacyl-3-(2-pyridyl)-1,2,4-triazines with 1,2-dehydrobenzene generated in situ from anthranilic acid and an excess of amyl nitrites afforded the target compounds in good yields. The proposed mechanism involves the in situ transformation of the 5-phenacyl group into the 5-cyano group under the action of alkyl nitrite and the following inverse demand aza-Diels–Alder reaction of thus formed 5-cyano-1,2,4-triazines with 1,2-dehydrobenzene affording the target products. The presence of the 5-phenacyl substituent is a key for the reaction, as in case of 5-styryl- or 5-phenylethynyl-3-(2-pyridyl)-1,2,4-triazines the formation of the 1,2,4-triazine ring-transformation products was observed
Acetylenic Ester Promoted Tandem Ring Opening of Dienyl Thiazolidin-4-ones and Cyclizations: A Facile and Chemoselective Synthesis of Functionalized Pyridine-2-carboxylates
Authors: Bhargava Gaurav , Kuila Bilash , Kumar Kapil , Mahajan Dinesh , Singh Prabhpreet
Published: November 2017

Acetylenic ester promoted ring opening of dienyl-thiazolidin-4-ones and subsequent electrocyclization affords 5-phenyl-6-aryl pyridine-2-carboxylates in good to excellent yields.
Monogenic Diabetes Not Caused By Mutations in Mody Genes: A Very Heterogenous Group of Diabetes
Authors: Şıklar Zeynep , de Franco Elisa , Johnson Matthew , Flanagan Sarah , Ellard Sian , Ceylaner Serdar , Boztuğ Kaan , Doğu Figen , İkincioğulları Aydan , Kuloğlu Zarife , Kansu Aydan , Berberoğlu Merih
Published: November 2017

Monogenic diabetes represents a heterogeneous group of disorders resulting from a single gene defect leading to disruption of insulin secretion or a reduction in the number of beta cells. Despite the classification of monogenic diabetes into neonatal diabetes or maturity onset diabetes of the young (MODY) according to age of onset, not every case can be classified into those 2 groups. We evaluated patients with monogenic diabetes diagnosed during the last 10 year period. Type 1 DM, MODY, and patients with negative autoantibodies and no mutation in a known gene were excluded from the study. Thirteen patients were diagnosed with monogenic diabetes in Department of Pediatric Endocrinology, Ankara University School of Medicine, Ankara, Turkey. Five of them were diagnosed after 6 months of age. Five had a KATP channel defect. Mutations in genes resulting in destruction of beta cells were detected in 7 patients, with 4 cases having a WFS, 2 an LRBA, and one a IL2RA mutation. Additional systemic findings were seen in 6/13 patients, with 5/6 having severe immune system dysfunction. Treatment with sulphonylurea was successful in two patients.. The other patients were given insulin in differing doses. Four patients died during follow-up, three of which had immune system dysfunction. Monogenic diabetes can be diagnosed after 6 months of age, even with positive autoantibodies. Immune dysfunction was a common feature in our cohort and should be investigated in all patients with early-onset monogenic diabetes. Mortality of patients with monogenic diabetes and additional autoimmunity was high in our cohort and is likely to reflect the multisystem nature of these diseases.
Methamphetaminkonsum während der Schwangerschaft und dessen Auswirkungen auf das Neugeborene
Authors: Pflügner Alina , Thome Ulrich , Bernhard Matthias , Vogel Mandy , Bläser Annett , Nickel Petra , Kiess Wieland
Published: November 2017

Hintergrund Methamphetamin (MA) gehört zu den meistgebrauchten illegalen Substanzen in der Schwangerschaft. Wir untersuchten die Effekte auf den Gestationsverlauf und die Gesundheit der Neugeborenen. 2004–2015 wurden im Universitätsklinikum Leipzig 102 Fälle von Neugeborenen dokumentiert, deren Mütter pränatal MA konsumierten.

Methoden In einer retrospektiven kontrollierten Studie wurden die Auswirkungen des pränatalen MA-Konsums auf das Neugeborene untersucht. Inhalt der Analyse waren u. a. Zeitpunkt der Schwangerschaftsfeststellung, Anzahl besuchter Vorsorgeuntersuchungen, Körpermaße der Neugeborenen, Dauer des postnatalen Krankenhausaufenthalts, Häufigkeit von Frühgeburten, auftretende Fehlbildungen und Symptome des NAS.

Ergebnisse Die Zahl MA-belasteter Neugeborener steigt seit einigen Jahren an. Bei der Mehrzahl der Konsumentinnen wurde die Gravidität im 2. Trimenon festgestellt; sie nahmen durchschnittlich 4 Vorsorgeuntersuchungen wahr. Die Zahl der Frühgeburten ist bei belasteten Kindern doppelt so hoch. Intrauterine Wachstumsretardierungen, Cardiopulmonale Adaptationsstörungen, Vitien und ein schlaffer Muskeltonus sind signifikant häufiger. Die mediane postnatale Verweildauer beträgt 10d (KG:5d). 44% der Kinder wurden in Obhut genommen (KG:0,98%). Der Altersmedian der Erstgebärenden beträgt 22,5a (KG:30a), 4,9% sind verheiratet (KG:38%). 57 der 102 Frauen sind arbeitslos oder -suchend.

Schlussfolgerung Die Auswirkungen des pränatalen MA-Gebrauchs erfordern multiprofessionelle Teamarbeit, um den Konsum frühzeitig zu detektieren, Nebenwirkungen vorzubeugen, die Kinder adäquat medizinisch zu behandeln und die Familien psychologisch und sozial zu unterstützen.
Ocean eddies and climate predictability
Authors: Kirtman Ben P. , Perlin Natalie , Siqueira Leo
Published: November 2017

A suite of coupled climate model simulations and experiments are used to examine how resolved mesoscale ocean features affect aspects of climate variability, air-sea interactions, and predictability. In combination with control simulations, experiments with the interactive ensemble coupling strategy are used to further amplify the role of the oceanic mesoscale field and the associated air-sea feedbacks and predictability. The basic intent of the interactive ensemble coupling strategy is to reduce the atmospheric noise at the air-sea interface, allowing an assessment of how noise affects the variability, and in this case, it is also used to diagnose predictability from the perspective of signal-to-noise ratios. The climate variability is assessed from the perspective of sea surface temperature (SST) variance ratios, and it is shown that, unsurprisingly, mesoscale variability significantly increases SST variance. Perhaps surprising is the fact that the presence of mesoscale ocean features even further enhances the SST variance in the interactive ensemble simulation beyond what would be expected from simple linear arguments. Changes in the air-sea coupling between simulations are assessed using pointwise convective rainfall-SST and convective rainfall-SST tendency correlations and again emphasize how the oceanic mesoscale alters the local association between convective rainfall and SST. Understanding the possible relationships between the SST-forced signal and the weather noise is critically important in climate predictability. We use the interactive ensemble simulations to diagnose this relationship, and we find that the presence of mesoscale ocean features significantly enhances this link particularly in ocean eddy rich regions. Finally, we use signal-to-noise ratios to show that the ocean mesoscale activity increases model estimated predictability in terms of convective precipitation and atmospheric upper tropospheric circulation.
Back-scattered electron visualization of ferroelectric domains in a BiFeO3 epitaxial film
Authors: Alyabyeva N. , Ouvrard A. , Lindfors-Vrejoiu I. , Ageev O. , McGrouther D.
Published: November 2017

Three-dimensional orientation of the ferroelectric (FE) domain structure of a BiFeO3 epitaxial film was investigated by scanning electron microscopy (SEM) using back-scattered electrons and piezoresponse-force microscopy (PFM). By changing the crystallographic orientation of the sample and the electron collection angle relative to the detector, we establish a link between the orientation of polarization vectors (out-of-plane and in-plane) in the BiFeO3 film and the back-scattered electron image contrast in agreement with PFM investigations. The different FE polarization states in the domains correspond to altered crystalline environments for the impingent primary beam electrons. We postulate that the resultant back-scattered electron domain contrast arises as a result of either differential absorption (through a channelling effect) or through back-diffraction from the sample, which leads to a projected diffraction pattern super-imposed with the diffuse conventional back-scattered electron intensity. We demonstrate that SEM can be sensitive for both out-of-plane and in-plane polarization directions using the back-scattered electron detection mode and can be used as a non-destructive and fast method to determine 3D FE polarization orientation of domains.
Biotemplated flagellar nanoswimmers
Authors: Ali Jamel , Cheang U Kei , Darvish Armin , Kim Hoyeon , Kim Min Jun
Published: November 2017

In this article, a porous hollow biotemplated nanoscale helix that can serve as a low Reynolds number robotic swimmer is reported. The nanorobot utilizes repolymerized bacterial flagella from Salmonella typhimurium as a nanotemplate for biomineralization. We demonstrate the ability to generate templated nanotubes with distinct helical geometries by using specific alkaline pH values to fix the polymorphic form of flagellar templates. Using uniform rotating magnetic fields to mimic the motion of the flagellar motor, we explore the swimming characteristics of these silica templated flagella and demonstrate the ability to wirelessly control their trajectories. The results suggest that the biotemplated nanoswimmer can be a cost-effective alternative to the current top-down methods used to produce helical nanorobots.