bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluating imaging repeatability of fully self-service fundus photography within a community-based eye disease screening setting
Authors: Zhang Juzhao , Luo Xuan , Li Deshang , Peng Yajun , Gao Guiling , Lei Liangwen , Gao Meng , Lu Lina , Xu Yi , Yu Tao , Lin Senlin , Ma Yingyan , Yao Chunxia , Zou Haidong
Published: March 2024

Purpose

This study aimed to investigate the imaging repeatability of self-service fundus photography compared to traditional fundus photography performed by experienced operators.

Design

Prospective cross-sectional study.

Methods

In a community-based eye diseases screening site, we recruited 65 eyes (65 participants) from the resident population of Shanghai, China. All participants were devoid of cataract or any other conditions that could potentially compromise the quality of fundus imaging. Participants were categorized into fully self-service fundus photography or traditional fundus photography group. Image quantitative analysis software was used to extract clinically relevant indicators from the fundus images. Finally, a statistical analysis was performed to depict the imaging repeatability of fully self-service fundus photography.

Results

There was no statistical difference in the absolute differences, or the extents of variation of the indicators between the two groups. The extents of variation of all the measurement indicators, with the exception of the optic cup area, were below 10% in both groups. The Bland–Altman plots and multivariate analysis results were consistent with results mentioned above.

Conclusions

The image repeatability of fully self-service fundus photography is comparable to that of traditional fundus photography performed by professionals, demonstrating promise in large-scale eye disease screening programs.
Successful retrieval of tip-embedded inferior vena cava filter using a modified forceps technique: case report
Authors: Liu Yang , Ma Junlong , Wang Qiqi , Zeng Wei , He Chunshui
Published: March 2024

Background

The retrieval of inferior vena cava (IVC) filter is essential for preventing complications associated with the device. Advanced techniques have been developed to improve the success rate of retrieving tip-embedded filters. The forceps technique is frequently used to address this issue.

Case presentation

We present a case study of two patients who underwent a successful tip-embedded IVC filter retrieval using a modified forceps technique, which has not been previously reported. This technique involves using a wire loop under the filter tip and a forceps to grasp the filter shoulder. By pulling the wire loop and pushing the forceps in counterforce, the filter tip is straightened and aligned with the vascular sheath. The vascular sheath can then dissect the filter tip out from the caval wall and get inside the sheath to complete the retrieval.

Conclusions

The modified forceps technique we present here offers a new solution for the complex retrieval of IVC filters.
Decreased levels of sex hormones in females with solitary pulmonary nodules were risk factors for malignancy
Authors: Wendan Wang , Mengyu Li , Qiufeng Zhang
Published: March 2024

Objective

The purpose of this research was to detect the relationship between the levels of sex hormones in females with solitary pulmonary nodules (SPNs) and their potential malignancies.

Methods

A total of 187 consecutive patients with pathologically confirmed SPNs by chest CT were enrolled in our study. They were divided into two groups based on the pathologic findings of SPNs after surgery: benign and malignant SPNs. Progesterone (P), estradiol (E2), and testosterone (T) levels in the two groups were measured. Meanwhile, we used binary logistic regression analysis to analyze the risk factors for SPNs.

Results

Of these 187 patients, 73 had benign SPNs, while 114 had malignant SPNs. We found that the levels of progesterone (P), estradiol (E2), and testosterone (T) were decreased significantly in patients with malignant SPNs compared to patients with benign SPNs (all P < 0.05). Multivariate logistic regression analysis revealed that second-hand smoke, burr sign, lobulation sign, pleural traction sign, vascular convergence sign, vacuole sign, and ≥ 1 cm nodules were independent risk factors for malignant pulmonary nodules in females.

Conclusions

Decreased levels of sex hormones in females were associated with malignant pulmonary nodules, suggesting that they can contribute to the diagnosis of lung cancer.
Nonketotic hyperglycemia hemichorea and hemiballismus: a case report
Authors: Dixit Abhishek
Published: March 2024

Background

Diabetic striatopathy, also known as hyperglycemic hemichorea-hemiballismus, is a rare movement disorder associated with nonketotic hyperglycemia in patients with poorly controlled diabetes mellitus. The pathophysiology is not fully elucidated but may involve hyperviscosity, ischemia, and alterations in basal ganglia neurotransmitters.

Case presentation

We present a case of a 64-year-old Asian female patient with longstanding poorly controlled type 2 diabetes mellitus who developed abrupt-onset right-sided hemichorea-hemiballismus. Laboratory results showed hyperglycemia without ketoacidosis. Neuroimaging revealed left putaminal hyperdensity on computed tomography and T1 hyperintensity on magnetic resonance imaging. With insulin therapy and tetrabenazine, her movements improved but persisted at 1-month follow-up.

Discussion

This case illustrates the typical features of diabetic striatopathy, including acute choreiform movements contralateral to neuroimaging abnormalities in the setting of nonketotic hyperglycemia. While neuroleptics may provide symptomatic relief, prompt glycemic control is critical given the risk of recurrence despite imaging normalization.

Conclusion

Diabetic striatopathy should be recognized as a rare disorder that can occur with poorly controlled diabetes. Further study of its pathophysiological mechanisms is needed to better guide management. Maintaining tight glycemic control is essential to prevent recurrence of this debilitating movement disorder.
Sustained mitigation of ST-segment elevation in a patient with Brugada syndrome type 1 during sevoflurane and remifentanil anesthesia: a case report
Authors: Saito Kurumi , Yoshida Hitoshi , Hirota Kazuyoshi
Published: March 2024

Background

During general anesthesia, patients with Brugada syndrome are at risk of malignant arrhythmias following worsened ST-segment elevation, potentially leading to sudden cardiac death. The protocol for safe anesthetic management of patients with Brugada syndrome has not yet been established.

Case presentation

A 63-year-old man, diagnosed with a spontaneous Brugada type 1 pattern, was scheduled for a pleural biopsy using video-assisted thoracoscopic surgery under general anesthesia. We planned general anesthesia using volatile induction and maintenance anesthesia with sevoflurane and remifentanil. We monitored ST-segment morphology and observed sustained mitigation of ST-segment elevation throughout general anesthesia.

Conclusion

The present case may indicate that safe anesthetic management of patients with Brugada syndrome depends on whether the anesthetics used can reduce ST-segment elevation.
P-wave propagation in attenuative elliptical VTI media
Authors: Hao Qi , Tsvankin Ilya
Published: March 2024

Elliptical anisotropy is convenient to use as the reference medium in perturbation methods designed to study P-wave propagation for transverse isotropy (TI). We make the elliptically anisotropic TI model attenuative and discuss the corresponding P-wave dispersion relation and the wave equation. Our analysis leads to two conditions in terms of the Thomsen-type parameters, which guarantee that the P-wave slowness surface and the dispersion relation satisfy elliptical equations. We also obtain the viscoacoustic wave equation for such elliptically anisotropic media and solve it for point-source radiation using the correspondence principle. For the constant- Q TI model, we use the weighting function method to derive the viscoacoustic wave equation in differential form. Numerical examples validate the proposed elliptical conditions and illustrate the behavior of the P wavefield in attenuative elliptical TI models.
Medicinal cannabis for treating post-traumatic stress disorder and comorbid depression: real-world evidence
Authors: Lynskey Michael T. , Athanasiou-Fragkouli Alkyoni , Thurgur Hannah , Schlag Anne Katrin , Nutt David J.
Published: March 2024

Background

Cannabis-based medicinal products (CBMPs) are increasingly being used to treat post-traumatic stress disorder (PTSD), despite limited evidence of their efficacy. PTSD is often comorbid with major depression, and little is known about whether comorbid depression alters the effectiveness of CBMPs.

Aims

To document the prevalence of depression among individuals seeking CBMPs to treat PTSD and to examine whether the effectiveness of CBMPs varies by depression status.

Method

Data were available for 238 people with PTSD seeking CBMP treatment (5.9% of the treatment-seeking sample) and 3-month follow-up data were available for 116 of these. Self-reported PTSD symptoms were assessed at treatment entry and at 3-month follow-up using the PTSD Checklist – Civilian Version (PCL-C). The probable presence of comorbid depression at treatment entry was assessed using the nine-item Patient Health Questionnaire (PHQ-9). Additional data included sociodemographic characteristics and self-reported quality of life.

Results

In total, 77% met screening criteria for depression, which was associated with higher levels of PTSD symptomatology (mean 67.8 v. 48.4, F(1,236) = 118.5, P < 0.001) and poorer general health, quality of life and sleep. PTSD symptomatology reduced substantially 3 months after commencing treatment (mean 58.0 v. 47.0, F(1,112) = 14.5, P < 0.001), with a significant interaction (F(1,112) = 6.2, P < 0.05) indicating greater improvement in those with depression (mean difference 15.3) than in those without (mean difference 7).

Conclusions

Depression is common among individuals seeking CBMPs to treat PTSD and is associated with greater symptom severity and poorer quality of life. Effectiveness of CBMPs for treating PTSD does not appear to be impaired in people with comorbid depression.
Glycerol Phenylbutyrate Treatment of 2 Patients With Monocarboxylate Transporter 8 Deficiency
Authors: Zung Amnon , Sonntag Niklas , Schweizer Ulrich , Banne Ehud , Braun Doreen
Published: March 2024

Context

Monocarboxylate transporter 8 (MCT8) deficiency is a rare genetic disease that leads to severe global developmental delay. MCT8 facilitates thyroid hormone (TH) transport across the cell membrane, and the serum TH profile is characterized by high T3 and low T4 levels. Recent studies have shown that the chemical chaperone sodium phenylbutyrate (NaPB) restored mutant MCT8 function and increased TH content in patient-derived induced pluripotent stem cells, making it a potential treatment for MCT8 deficiency.

Objective

We aimed to assess the efficacy and safety of glycerol phenylbutyrate (GPB) in MCT8 deficiency.

Methods

We treated 2 monozygotic twins aged 14.5 years with MCT8 deficiency due to P321L mutation with escalating doses of GPB over 13 months. We recorded TH, vital signs, anthropometric measurements, and neurocognitive functions. Resting metabolic rate (RMR) was measured by indirect calorimetry. Serum metabolites of GPB were monitored as a safety measure. In vitro effects of NaPB were evaluated in MDCK1 cells stably expressing the MCT8P321L mutation. The effects of GPB were compared to the effects of DITPA and TRIAC, thyromimetic medications that the patients had received in the past.

Results

NaPB restored mutant MCT8 expression in MDCK1 cells and increased T3 transport into cells carrying the P321L mutation. GPB treatment reduced high T3 and increased low T4 levels. The patients showed a significant weight gain simultaneously with a reduction in RMR. Only minor neurocognitive improvement was observed, in hyperreflexia score and in cognitive functions. Serum metabolites did not exceed the toxic range, but elevated liver transaminases were observed.

Conclusion

In the first report of GPB treatment in MCT8 deficiency we found an improvement in TH profile and body mass index, with minor neurodevelopmental changes.
The BDNF Protein is Associated With Glucose Homeostasis and Food Intake in Carriers of Common BDNF Gene Variants
Authors: Miksza Urszula , Bauer Witold , Roszkowska Joanna , Moroz Monika , Buczynska Angelika , Wiatr Aleksandra , Gorska Maria , Adamska-Patruno Edyta , Kretowski Adam
Published: March 2024

Context

Brain-derived neurotrophic factor (BDNF) concentrations may differ between BDNF genotype carriers. These changes occur in individuals with metabolic and mental disorders.

Objective

The aim of this study was to assess the associations of glucose homeostasis parameters and the frequency of food consumption with BDNF protein concentrations based on BDNF single nucleotide polymorphisms (SNPs).

Methods

Among the 439 participants, some common rs10835211 BDNF gene variants were analyzed. We evaluated BDNF concentrations, and measured glucose and insulin after fasting and during oral glucose tolerance tests. Anthropometric measurements, body composition, and body fat distribution were assessed, and a 3-day food intake diary and food frequency questionnaire were completed.

Results

We observed significant differences in BDNF concentration between AA and AG genotype rs10835211 carriers (P = .018). The group of AA genotype holders were older, and positive correlation was found between age and BDNF in the whole study population (P = .012) and in the GG genotype carriers (P = .023). Moreover, BDNF protein correlated with fasting insulin (P = .015), HOMA-IR (P = .031), HOMA-B (P = .010), and the visceral/subcutaneous adipose tissue (VAT/SAT) ratio (P = .026) in the GG genotype individuals. Presence of the GG genotype was negatively correlated with nut and seed (P = .047) and lean pork consumption (P = .015), and the BDNF protein. Moreover, we observed correlations between the frequency of chicken (P = .028), pasta (P = .033), and sweet food intake (P = .040) with BDNF concentration in the general population. Among carriers of the AA genotype, we observed a positive correlation between the consumption of rice (P = .048) and sweet food (P = .028) and the BDNF protein level.

Conclusion

Peripheral BDNF may be associated with VAT content and insulin concentrations in GG genotype carriers and may vary with particular food intake, which warrants further investigation.
Elagolix Represents a Less Invasive and Cheaper Option Than Injectable GnRH Antagonist for Ovulation Suppression in IVF
Authors: Mouanness Marco , Merhi Zaher
Published: March 2024

Background

The injectable gonadotropin-releasing hormone (GnRH) antagonists have traditionally been used for ovulation suppression during controlled ovarian hyperstimulation for in vitro fertilization (IVF), leading to increased painful daily injections and cost. The use of the oral GnRH antagonist elagolix for ovulation suppression in IVF has not been studied.

Methods

This retrospective cohort study of patients undergoing IVF who received either oral elagolix 50 mg every other day or ganirelix/cetrotide injection daily for ovulation suppression during controlled ovarian hyperstimulation included 269 patients, 173 in the elagolix group and 96 in the ganirelix/cetrotide group. The main outcome was the suppression of luteinizing hormone (LH) blood levels, reflecting ovulation suppression.

Results

Age, body mass index, anti-Müllerian hormone, baseline follicle-stimulating hormone, antral follicles count, dose of medications used, number of days of ovarian stimulation, and peak estradiol (E2) levels were similar in both groups. When blood LH and E2 levels were measured before intake and the day after intake of either elagolix or ganirelix/cetrotide, both groups had significant and similar drop in LH levels and increase in E2 levels. When comparing IVF cycle outcomes in both groups, the number of oocytes retrieved, number of mature oocytes, fertilization rate, blastocyst formation rate, euploidy rate, and endometrial lining thickness at the time of the trigger were all similar.

Conclusion

Oral GnRH antagonist, a much cheaper and less invasive medication that is used at a lower frequency, showed comparable ovulation suppression to the costly injectable GnRH antagonist. Further studies are required to evaluate the effect of oral GnRH antagonist on endometrial lining receptivity and pregnancy outcomes, especially when using fresh embryo transfer IVF protocols.
Między teorią a wiedzą źródłową. Nowe spojrzenie na rolę saskiej Kamery jako prekursora prób modernizacji Rzeczypospolitej w XVIII wieku
Authors: Dygdała Jerzy
Published: March 2024

Omówienie treści książki Petera Collmera poświęconej funkcjonowaniu saskiej administracji majątków królewskich w Rzeczypospolitej w latach 1700–1763. Dyskusja z niektórymi tezami Autora. Kwestia modelu modernizacji wczesnonowożytnego państwa europejskiego na przykładzie szlacheckiej Rzeczypospolitej w XVIII w.
Wysiłki na rzecz ugody z Rosją. Publicystyka i aktywność polityczna Henryka Lisickiego w przededniu i w czasie wojny rosyjsko-tureckiej 1877–1878
Authors: Nowak Mariusz
Published: March 2024

W artykule dokonano analizy działań krakowskiego konserwatywnego publicysty Henryka Lisickiego w ramach aktywizacji środowiska ugodowego w Królestwie Polskim z Zygmuntem Wielopolskim na czele w końcu 1876 r. Wykorzystując zaangażowanie Rosji w konflikt na Bałkanach, dążyło ono do nakłonienia jej do odejścia od polityki represji i przywrócenia niektórych mechanizmów autonomicznych Królestwa. Środkiem ku temu było opracowanie, przy współudziale Lisickiego, broszury i adresu do cara. Mimo lojalistycznych deklaracji ze strony grupy Wielopolskiego Petersburg nie odpowiedział na ofertę ugodowców.
Straty żołnierzy armii rosyjskiej pochodzących z gminy Gródek powiatu białostockiego guberni grodzieńskiej podczas I wojny światowej
Authors: Dmitruk Stefan
Published: March 2024

Straty w armii rosyjskiej z I wojny światowej dotknęły ok. 55% wszystkich walczących w niej żołnierzy. Wśród ofiar byli rekruci pochodzący z gminy Gródek powiatu białostockiego guberni grodzieńskiej, czyli terenów wchodzących obecnie w skład województwa podlaskiego. Ubytki żołnierzy wpływały na życie społeczne po Wielkiej Wojnie – szczególnie na Białostocczyźnie dotkniętej działaniami wojennymi i ewakuacją z 1915 r. Problem strat z wymienionego obszaru nie został kompleksowo zbadany w polskiej historiografii. Autor analizuje straty żołnierzy i podoficerów walczących w mundurze armii rosyjskiej w latach 1914–1918, pochodzących z rejonu Gródka.
OUN i UPA na Łemkowszczyźnie Zachodniej
Authors: Mazur Przemysław
Published: March 2024

Artykuł przedstawia działalność ukraińskich formacji nacjonalistycznych (Organizacji Ukraińskich Nacjonalistów – OUN i Ukraińskiej Powstańczej Armii – UPA) na Łemkowszczyźnie, jak również skalę poparcia dla nich wśród Łemków. Celem było zweryfikowanie intensywności tych zjawisk i uzasadnienia przesiedlenia ludności łemkowskiej w ramach akcji „Wisła”. Ponadto szukano odpowiedzi na pytanie, czy przesiedlenia były jedyną możliwością zaprowadzenia spokoju w tej części Polski, czy też wpisują się w pojęcie strategicznej broni demograficznej i mogą być inspirowane podobnymi działaniami podjętymi w Związku Radzieckim?
Meet the Jury
Authors: Roper Jack
Published: March 2024

At the opening ceremony of each biennial Intertraffic Amsterdam, the Intertraffic Awards are presented to the most groundbreaking new technology to be launched since the last event. We meet the industry insiders who have the difficult task of deciding on the winners, from well over 100 entries to each edition
Green Leaders
Authors: Gerden Eugene
Published: March 2024

The Netherlands, host nation for Intertraffic Amsterdam, has long led the world in promoting active travel and multimodality. We take a look at the initiatives now underway in its two largest urban centres in the drive towards net zero, and find out how policy makers are not only focused on improving mobility but enhancing liveability
Hazards Ahead?
Authors: Court-Dobson Christopher
Published: March 2024

The NordicWay project is proving that safety-improving connected vehicle systems are achievable using just the cellular network, but are all parties equally committed to Vision Zero?
Avoiding Conflict
Authors: Roper Jack
Published: March 2024

Urban air mobility is widely believed to be the next era of transportation – with Intertraffic Amsterdam in April 2024 collocated with Amsterdam Drone Week. But before we can all start zipping around at low altitudes, the challenges of managing this new kind of traffic must be solved
Seamless Operations
Authors: Gkikas Andreas
Published: March 2024

An innovative SaaS solution supports contractors throughout a project’s lifecycle, while establishing a transparent and cooperative environment between contractors and clients
Changing the Safety Landscape
Authors: Al Shamlan Eisa
Published: March 2024

A range of innovative and versatile safety systems have been designed to make highways safer and more efficient for all road users
Intelligent Synergy
Authors: Tognacca Roberto
Published: March 2024

A collaborative effort and combination of expertise led to a successful solution that improves safety and optimises traffic management in Italy
Powerful Investments
Authors: Sørlie Sara
Published: March 2024

Technology is the driving force behind innovation and progress in the road safety industry
Parking and Powering
Authors: Terricabras Roger
Published: March 2024

Investing in modern EV charging infrastructure and smart car park management tech is a must for parking facility owners if they want to reduce costs, drive revenues and attract new customers, Circontrol reports
BİR DEVİR ÜSLUBUNUN BİR BÖLGE KARAKTERİNE DÖNÜŞÜ: ÇIKRIK CAMİİ KALEM İŞİ SÜSLEMELERİ
Authors: KARAÇAY Çiğdem
Published: March 2024

ÖZ: Çıkrık Köyü günümüzde Çorum’un merkez ilçesine bağlıdır. Çıkrık Camii köy merkezinde yer almaktadır. Caminin inşa kitabesi bulunmamaktadır. Vakıf kayıtları arşivinde 1843 tarihli hatip ve imam atamasına dair belge caminin 19. yüzyılın ilk yarısında mevcudiyetini göstermektedir. Caminin giriş kapısı üzerinde yer alan tabelada 1904 tarihi okunmaktadır. Bu tarih caminin geçirdiği köklü bir onarıma ait olmalıdır. Camide gerçekleştirilen onarımlar caminin işlevselliğine yöneliktir. Camide işlevselliğe olduğu kadar estetik değerlere de önem verildiği harim mekânına girildiğinde anlaşılmaktadır. Harimde turkuaz rengin hâkim olduğu bitkisel motifler ve yazıdan müteşekkil kalem işi nakışlar yeni tarihlidir. Bu nakışlar sanatsal yaratımdan ziyade bir devrin geleneğinin bir bölge karakterine dönüşünü göstermesi açısından önemlidir. Bu çalışmanın amacı Çorum’da yüzyıllardır camileri süsleyen kalem işi nakış geleneğini Çıkrık Camii bağlamında irdelemektir. Çalışmada öncelikle Çıkrık Camii mimari ve süsleme özellikleri tanıtılarak belgelenmiştir. Ardından il merkezinden ilçelere ve köylere yayılan geleneğin kilit taşı olması sebebiyle Çorum, Çıkrık Köyü’nün 1990’lı yıllara kadar Mecitözü’ne bağlı bir köy olmasından kaynaklı Mecitözü ve Mecitözü’ne bağlı köylerde tespit edilen kalem işi nakışlarla süslü camilere bu çalışmada yer verilmiştir. Bahsi geçen bölgelerde camileri kalem işi nakışlarla süslemenin bir dönem üslubu olarak 18. yüzyıldan itibaren görüldüğünü, günümüzde ise geleneksel estetikçi anlayış ile kültürel pratiğe dönüştüğünü söylemek mümkündür.
20.YÜZYIL ÖZELİNDE BAZI GELENEKSEL KADIN GİYSİLERİNİN KORUNARAK SAKLANMASI
Authors: ÖNGEN Ayşe Gamze
Published: March 2024

Türklerde giyim-kuşam, önemli kültürel bir değer olarak, öne çıkmaktadır. Bu nedenle, tarihi giysilerin bilinirliliğini sağlamak adına, bu eserlerin gelecek nesillere aktarılabilmesi için korunarak saklanmalırı gerekir. Bu çalışma, tarihi giysilerin korunarak saklanması ve sergilenmesi için uygun çevresel koşulların sağlanmasının önemini vurgulamaktadır. Çünkü giysilerin saklandığı veya sergilendiği ortamların çevresel koşulları, eserlerin zarar görmesinde önemli bir etkendir. Ayrıca, insan faktörü de giysiler üzerinde olumsuz etkiler yaratmaktadır.

Çalışma kapsamında, 20. yüzyıla ait özel bir koleksiyonda yer alan 50’ye yakın kadın giysi örneğinden seçilen 3 eser incelenmiştir. Geleneksel kadın giysi örneklerinin incelenme amacı, bu eserlerin doğal malzemelerle üretilmelerinden kaynaklanan olumsuz çevresel faktörlerden, nasıl etkilendiklerini tespit etmektir. Bu şekilde, kadın giysilerinin saklandığı koşulların elverişsizliği ve olumsuz faktörlerin eserler üzerindeki tahribatıyla birlikte, özellikle insan faktörünün etkisinin de önemli olduğu görülmektedir. Zira, ülkemizde evlerde elverişsiz koşullarda konservasyon bilgisine sahip olmayan kişiler tarafından saklanan birçok kültürel değerin olduğu düşünüldüğünde, koruyucu konservasyon bilgilerinin paylaşılması ve görsel verilerle desteklenmesi önemli bir hedeftir. Ayrıca, günümüze kadar ulaşabilen tarihi giysilerin daha fazla yıpranmaması için gerekli yöntemler, gelişen teknolojik bilgilerden faydalanılarak eserler incelenmiştir. Bu bağlamda, tekstillerin ömürlerini uzatmaya yönelik önemli bilgilerin gelecek nesillere aktarılması hedeflenmiştir. Ancak, tarihi giysilerin korunması için uygulanan koruyucu yöntemlere dair sınırlı sayıda bilimsel çalışma bulunmaktadır. Bu nedenle, çalışmanın literatüre özgün bir katkı sağlaması hedeflenmiştir. Ayrıca kültürel varlıklarımızın gelecek kuşaklara aktarılmasını güvence altına almak adına koruyucu konservasyon yöntemlerinin daha geniş bir perspektifte ele alınması gerektiği vurgulanmıştır.
Minor Settler Grief: Korean Diaspora, Settler Colonialism, and the Pastoral Fantasy in Minari (2021)
Authors: We Jeong Eun Annabel
Published: March 2024

Abstract: The critically acclaimed film Minari (2021), directed by Lee Isaac Chung, has been recognized for its emotionally moving on-screen representation of a rural Asian American experience. Building on transpacific scholarship, the present essay examines Minari as a narrative of "minor settler grief," an expression of grief by minor settlers that is closely tied to colonial and militarized aesthetics of earth across the Pacific. The article ties Minari's Korean American farming efforts in 1980s Arkansas to the intersecting histories of settler colonialism in the US and Japanese empires and South Korean authoritarian developmentalism. It considers the Korean nativist aesthetics of earth at work in Minari , an aesthetics of pastoral fantasy that had served imperialism and authoritarian developmentalism, as well as anticolonial imaginations in modern Korea and the diaspora. The essay argues that minor settler grief functions by obscuring relationalities, such as the histories of Native American removal in present-day Arkansas. Mining these histories and visual references enables a critique of certain expressions of grief that produce settler colonial recognition and forgetting.
Osaki Midori: The World of Wandering in the Realm of the Seventh Sense (Part 1) / 尾崎翠・「第七官界彷徨」の世界
Authors: Noriko Mizuta , Yasuko Wachi , Cullen Jennifer
Published: March 2024

Abstract: Osaki Midori (1896–1971) left behind only a few literary works before returning to her home in Tottori and falling silent. Yet these few avant-garde texts are now recognized as crucial to the study of Japanese women’s modernist literature. As a woman writer who ignored the strict gender divisions of her time, her works continue to resonate with readers today. The mystery behind her forced return to Tottori and retirement from writing has prompted new attention to her life story, which seems to illustrate the conflict for women between a literary career and family obligations, and the realms she created in avant-garde prose that transcend the bounds of reality.
Staying with Narrative: Stories of Shame and Gynecological Pain
Authors: Cheston Katharine
Published: March 2024

Abstract: Storytelling is good for us—or so we are told. This article examines two memoirs, by Hilary Mantel and Susanna Kaysen, in which narrating experiences of gynecological pain provokes shame and deepens pain. By attending to shame as a textual presence, I intervene in a longstanding debate about how to make sense of pain and illness. Shame, I argue, reveals the presence of multiple (and often contrasting) illness narratives ; I analyze these narratives, and their interplay, across Mantel's and Kaysen's memoirs. As scholarship moves beyond, past, or post-narrative, I urge us to stay: to interrogate the ways in which illness narratives interact—amplifying some stories and storytellers whilst fragmenting or silencing others—and to examine the responsibility we all have within this collective sense-making.
Trans*-itional Longings of the “Dark Ghetto”: Rosa Guy and a Trans* Black Childhood Studies
Authors: Knadler Stephen
Published: March 2024

Abstract: “Trans*-itional Longings” argues that the neglected Black Arts Movement writer Rosa Guy traces out a model of trans* Black childhood in her essays and fiction that is informed by the materiality and lived experience of antiblack necropolitics in “ghetto” ecologies. Guy offers a different entry point and genealogy for a “quared” Black childhood studies that is more than an extension of white queer childhood studies. In her essays and fiction, Guy witnesses that the trans* Black child of Harlem is a figure of improvisational Black aliveness “trans-itioning” into alternative Black futures.
The Untimely Impersonal
Authors: Manning Erin
Published: March 2024

Abstract: The untimely impersonal moves at the pace of neurodiverse time. Neurodiverse time is time out of time, time devoid of executive function, time not only nonlinear but fundamentally ungraspable as a line or a block. Incalculable to its core, without a timeline, neurodiverse time is terrifying in its infradimensionality, exuberant in its yield. In this essay, my proposition is to take us on a journey through the constraints and conditions of the untimely impersonal to ask how else the living (and learning) happens when time moves out of the metric of the executive.
A Q&A with Erin Manning
Authors: Manning Erin
Published: March 2024

Abstract: The following exchange took place during the Question and Answer period following Erin Manning’s (EM) talk, “The Untimely Impersonal.” The talk was given digitally on 22 September 2021 as part of Relative Time/Little Time , a speaker series designed collaboratively by Dutch artist duo Bik Van der Pol and Mosaic . The Question and Answer session was moderated by Mosaic Editor Shepherd Steiner (SS).
Sleep Through This Article: On Imagining Sleep in Canada
Authors: Huebener Paul
Published: March 2024

Abstract: I argue that representations of sleep in Canada can illuminate and challenge how sleep operates as a contested cultural figure. Focusing on advertisements from Sleep Country Canada and other examples, I show how we can develop a critical literacy of sleep in a restless world.
A Q&A with Paul Huebener
Authors: Huebener Paul
Published: March 2024

Abstract: The following exchange took place during the Question and Answer period following Paul Huebener’s (PH) talk, “Sleep Through This Talk: Imagination and the Paradox of Sleep in a Restless World.” The talk was given digitally on 26 January 2022 as part of Relative Time/Little Time , a speaker series designed collaboratively by Dutch artist duo Bik Van der Pol (LB and JVdP) and Mosaic . The Question and Answer session was moderated by Mosaic Editor Shepherd Steiner (SS).
A Q&A with Anna-Sophie Springer and Etienne Turpin
Authors: Springer Anna-Sophie , Turpin Etienne
Published: March 2024

Abstract: The following exchange took place during the Question and Answer period following Anna-Sophie Springer (AS) and Etienne Turpin’s (ET) talk, “How Long Has This Been Going On: Natural History, Political Economy, and the Times of the Anthropocene.” The talk was given digitally on 3 March 2022 as part of Relative Time/Little Time , a speaker series designed collaboratively by Dutch artist duo Bik Van der Pol (LB and JVdP) and Mosaic . The Question and Answer session was moderated by Mosaic Editor Shepherd Steiner (SS).
Climate Change as Oppressor: Our Growing Ecological Imperative
Authors: Duval Steven , McDougall Marina
Published: March 2024

Abstract: In this presentation and conversation melding philosophy, cultural history, and contemporary practice, artist/curator Steven Duval and curator Marina McDougall engage Felix Guattari’s The Three Ecologies as a framework to assert the essential value of the arts in contemporary public works projects, or potential future Green New Deal.
Pixels, Politics, and Privileges in Doctorow and Wang's In Real Life
Authors: Helton Tena L. , Dong Lan
Published: March 2024

Abstract: This article argues that the graphic narrative form of Cory Doctorow's and Jen Wang's In Real Life draws the reader's attention to the complex social space of MMORPGs, especially for young adults as they encounter the challenges of gender and global economic politics in virtual space as well as in real life. Through teen gamer Anda's perspective, the narrative engages the politics of embodiment in virtual and real spaces and reveals the limitation of her naïve and privileged political participation.
A Real Evidence of Community: Poll Worker Portraits in the North Carolina Piedmont
Authors: Medley Kate
Published: March 2024

Abstract: Georgia poll workers came under fire for alleged election fraud in the 2020 presidential election, but the accusations stood in stark contrast to the author's own experiences as a poll worker in North Carolina during the same election. The author, a photographer, visited a few precincts in central North Carolina to ask volunteers why they became poll workers and to discuss their duty to ensure all voters who showed up were able to cast a ballot and have it counted. Some poll workers talked about voting rights; many described their own voting history and the changes they've witnessed. Others talked about misinformation and the news media. All mentioned integrity, asking themselves: As a citizen and as a poll worker, what can I do to help ensure that each person in my community has the opportunity to vote on Election Day and have that vote counted?
Jaynes-Cummings interaction with a traveling light pulse
Authors: Mølmer Klaus , Christiansen Victor Rueskov , Lund Mads Middelhede , Yang Fan
Published: March 2024

The Jaynes-Cummings model provides a simple and accurate description of the interaction between a two-level quantum emitter and a single mode of quantum radiation. Due to the multimode continuum of eigenmodes in free space and in waveguides, the Jaynes-Cummings model should not be expected to properly describe the interaction between an emitter and a traveling pulse of quantum radiation. In this article, we review a cascaded quantum system approach that accurately describes the interaction of a quantum system with an incident quantum pulse of radiation. This approach leads to different formulations of the theory, each of a similar structure as the Jaynes-Cummings model but with important modifications.
De novo transcriptomic analysis of Doum Palm (Hyphaene compressa) revealed an insight into its potential drought tolerance
Authors: Borlay Allen Johnny , Mweu Cecilia Mbithe , Nyanjom Steven Ger , Omolo Kevin Mbogo , Naitchede Labode Hospice Stevenson
Published: March 2024

Background

Doum palms (Hyphaene compressa) perform a crucial starring role in the lives of Kenya’s arid and semi-arid people for empowerment and sustenance. Despite the crop’s potential for economic gain, there is a lack of genetic resources and detailed information about its domestication at the molecular level. Given the doum palm’s vast potential as a widely distributed plant in semi-arid and arid climates and a source of many applications, coupled with the current changing climate scenario, it is essential to understand the molecular processes that provide drought resistance to this plant.

Results

Assembly of the first transcriptome of doum palms subjected to water stress generated about 39.97 Gb of RNA-Seq data. The assembled transcriptome revealed 193,167 unigenes with an average length of 1655 bp, with 128,708 (66.63%) successfully annotated in seven public databases. Unigenes exhibited significant differentially expressed genes (DEGs) in well-watered and stressed-treated plants, with 45071 and 42457 accounting for up-regulated and down-regulated DEGs, respectively. GO term, KEGG, and KOG analysis showed that DEGs were functionally enriched cellular processes, metabolic processes, cellular and catalytic activity, metabolism, genetic information processing, signal transduction mechanisms, and posttranslational modification pathways. Transcription factors (TF), such as the MYB, WRKY, NAC family, FAR1, B3, bHLH, and bZIP, were the prominent TF families identified as doum palm DEGs encoding drought stress tolerance.

Conclusions

This study provides a complete understanding of DEGs involved in drought stress at the transcriptome level in doum palms. This research is, therefore, the foundation for the characterization of potential genes, leading to a clear understanding of its drought stress responses and providing resources for improved genetic modification.
Comparative study between biliary covered self-expandable metal stent and conventional endoscopic bile drainage treatment in endoscopic retrograde cholangiopancreatography-related Stapfer type II retroperitoneal perforations
Authors: Heo Jun , Jung Min Kyu , Lee Jieun , Lee Dong wook , Cho Chang Min , Cha Jung Guen
Published: March 2024

Background

Perforation is one of the most serious complications of endoscopic retrograde cholangiopancreatography (ERCP). Conventional nonsurgical endoscopic treatments including intravenous antibiotic administration and plastic endoscopic biliary drainage are generally approved for the treatment of ERCP-related Stapfer type II perforation (perivaterian type). Biliary covered metal stent placement has recently been reported to have favorable outcomes in ERCP-related Stapfer type II perforations. We aimed to compare the outcomes of conventional endoscopic bile drainage and biliary covered self-expandable metal stent (SEMS) insertion in patients with Stapfer type II perforation.

Methods

Medical records of patients who underwent ERCP at Kyungpook National University Hospital in Daegu from 2011 to 2022 were retrospectively reviewed.

Results

A total of 8,402 ERCP procedures were performed in our hospital. Sixty-six ERCP-related perforations (0.78%) were identified. Among them, 37 patients (56.1%) who had Stapfer type II perforations were enrolled. Thirteen and twenty-four patients received biliary covered SEMS insertion and conventional endoscopic bile drainage treatments, respectively. No significant differences were observed in the clinical success rate (92.3% vs. 91.7%, p = 1.000), hospital stay (9.46 ± 5.97 vs. 13.9 ± 13.2 days, p = 0.258), and post-ERCP–related fasting time (5.4 ± 3.4 vs 4.3 ± 3.0 days, p = 0.305). Complications including bleeding, post-ERCP pancreatitis, fever, and death were not significantly different between the two groups. The conventional endoscopic bile drainage group took less time for ERCP than the SEMS group (11.5 ± 5.2 vs. 18.5 ± 11.2 min, p = 0.013).

Conclusions

Compared with the conventional endoscopic bile drainage treatment method, biliary covered SEMS did not improve patient outcomes in ERCP-related Stapfer type II perforations.
How The Danish Girl was adapted and recontextualized through multimedia
Authors: Zhang Zhen
Published: March 2024

The Danish Girl has three different versions – novel, screenplay and film. Through comparison, this study explored how Lucinda Coxon (2015) and Tom Hooper (2015) adapted David Ebershoff’s novel (2000), The Danish Girl, to the screenplay and the film of the same name, and how multimodal semiotic resources contributed to recontextualizing the screenplay and the film. This research selected a scene, which represented the ‘remade’ type, from The Danish Girl to instantiate recontextualization in depth. The study found that the adaptations of The Danish Girl mixed different methods. The study also found that the way of recontextualizing the film was more complex than that of the screenplay.
One-Year Comparative Effectiveness of Upadacitinib vs Tofacitinib for Ulcerative Colitis: A Multicenter Cohort Study
Authors: Dalal Rahul S. , Kallumkal Govind , Cabral Heidy J. , Barnes Edward L. , Allegretti Jessica R.
Published: March 2024

INTRODUCTION:

The comparative effectiveness of upadacitinib and tofacitinib for ulcerative colitis (UC) is poorly understood.

METHODS:

In this retrospective cohort study, we compared steroid-free clinical remission (SFCR) and endoscopic response/remission at 52 weeks among adults initiating upadacitinib or tofacitinib for UC.

RESULTS:

A total of 155 patients initiated upadacitinib (n = 81; 30% prior tofacitinib exposure) or tofacitinib (n = 74; 0% prior upadacitinib exposure). After inverse probability of treatment-weighted logistic regression, upadacitinib was associated with significantly higher odds of SFCR (odds ratio 3.01, 95% confidence interval 1.39–6.55) vs tofacitinib. There were no differences for endoscopic response/remission.

DISCUSSION:

Upadacitinib was more effective at achieving SFCR in UC at 52 weeks vs tofacitinib.
The Time House: between cybernetics and phenomenology
Authors: Ioannidou Ersi
Published: March 2024

Martin Pawley’s ‘The Time House’ (1968) is a study on how to use multimedia technologies to provide a continuous record of individual experience within the domestic interior. The project’s underlying argument is that there is no authentic experience to be had in the public realm. As an antidote, Pawley proposes a retreat into a private world, where individuals, with the use of technology, can retain a continuous and repayable record of time. Thus, The Time House would enable its inhabitants to relive – phenomenologically, with all the senses – past experiences. Pawley believed that this repeated, unembellished re-creation of the past would reveal to its inhabitants a truer version of both the past and themselves, thus offering opportunities for introspection and self-knowledge. The Time House tries to bring together all the key concerns of architecture in the late 1960s: cybernetics, phenomenology, environmental behaviour studies, the use of cutting-edge technology, Cold War politics and fears, and the countercultural aim to expand human consciousness. Yet, Pawley’s proposition to use technology to simulate lived experiences with the aim of altering human behaviour still stimulates heated arguments today. These arguments stem from current fears about the effects of digital technologies on individuals and society: the disconnection with the here-and-now, the prioritisation of the individual over the collective, the disintegration of reality and the neglect of social public space. The Time House, which could be dismissed as a project of its time and place, is embedded in a web of ideas still resonant in our present.
Assessment of sperm acrosome status, malondialdehyde and aspartate aminotransferase enzyme concentration of frozen semen from Limousin and Simmental bulls in different commercial diluents
Authors: Tahar Muhammad Agus , Komariah Komariah , Nuraini Henny , Maulana Tulus , Gunawan Muhammad , Arifiantini R Iis
Published: March 2024

Sperm cryopreservation is the process of preserving sperm cells at low temperatures, so that its frozen semen can be used in the future. The quality of the frozen sperm is affected by the diluent. The objective of this study was to compare the effects of commercial diluents on acrosome status, malondialdehyde (MDA) and aspartate aminotransferase (AspAT) enzyme concentration of thawed Limousin and Simmental bull semen. Semen was collected twice weekly using an artificial vagina. The fresh semen processed into frozen semen hadÂ  sperm motility of 70%. The one-step procedure was used for the dilution methods. AndromedÂ®, OptixcellÂ® and SteridylÂ® were used as diluents. Data were analyzed by analysis of variance (ANOVA) followed by Tukey HSD 5% confidence interval. The result showed no interaction (P0.05) between two factors on acrosome status. The sperm acrosome damage of Simmental in SteridylÂ® was significantly lower than others (P0.05), although all diluents showed low sperm acrosome damage. Also, no interaction between the type of diluent and breed on MDA and AspAT enzyme concentrations was detected (P0.05). The results suggest that three commercial diluents have equal efficacy in protecting acrosome status and maintaining MDA and AspAT enzyme concentrations of frozen Limousin and Simmental bull semen. Therefore, all commercial diluents can be an alternative for Limousin and Simmental frozen semen.
Effect of Carbohydrate Type and Phenotype on the Quality of Post-Thawing Frozen Semen of KUB Chicken
Authors: Maghfira Maghfira , Karja Ni Wayan Kurniani , Arifiantini R. Iis , Sartika Tike
Published: March 2024

The superior Balitbangtan Kampung Chicken (KUB) chickens have different phenotypes. It was reported that the chicken phenotype was related to semen quality. This study aimed to determine the post-thawing characteristics and quality of KUB chicken semen with different phenotypes frozen in Ringer's lactate egg yolk (RLEY) diluent with the addition of fructose or glucose. Semen was collected using the massaging method from 20 KUB chickens with a single comb phenotype and black or dark brown feather color with a red feather neck (SCNR), green-black single comb with white feather neck collar (SCNW), pea comb and black feathers or dark brown fur with a red neck (PCNR), and a green-black pea comb with a white neck (PCNW). Semen from each chicken phenotype was divided into three parts or frozen in three types of diluents: RLEY, RLEY+fructose (RLEYF), and RLEY+glucose (RLEYG). The highest sperm motility was found in the diluent with the addition of glucose in the SCNR and PCNW phenotypes (P0.05). The highest sperm viability was shown in the RLEYG diluent in the PCNW phenotype (P0.05). The highest abnormality was found in the RLEY and RLEYF diluents in the SCNW, PCNR, and PCNW groups, whereas in the RLEYG group, it was only found in the PCNR group. From the results of this study, it can be concluded that the type of glucose and chicken phenotype influences the quality of post-thawing semen. The best is found in diluents with glucose attachments in the SCNR phenotype.