bluuebunny/crossref_metadata_2025 huggingface dataset:
Lactic acid bacteria
Authors: Atwa Nagwa A. , Wahba Marwa I. , Maany Dina A. , Awad Hassan M. , Abo-Alkasem Mohamed I. , El-Masry Hossam M. , Amer Mai N. , El-Diwany Ahmed I.
Published: August 2022

Background

In a previous study, a lactic acid bacterium, Enterococcus faecium, was locally isolated from Egyptian soil and its ability to inhibit the growth of a test phytopathogen was proven.

Objective

The study was performed to assess the ability of the tested strain to grow on different media. The produced antifungal agent was investigated. Finally, the strain was encapsulated within different biopolymers to increase its viability.

Materials and methods

Several byproducts were tested and compared with the standard De Man-Rogosa-Sharpe medium. The antifungal activity was tested using the poisoned food technique. Chromatographic analysis of the fermentation medium was performed using high-performance liquid chromatography. Production of chitinase was confirmed by cultivating the test strain on chitin and estimating the amount of reducing sugars using the Somogyi method. The E. faecium cells were also encapsulated within soy protein isolate-alginate beads, gellan gum discs, and carboxymethyl cellulose beads.

Results and conclusion

The strain was able to grow on all of the tested byproducts and exerted a potent antifungal activity against Fusarium solani, especially when a very economic medium, mainly composed of whey, was used. High-performance liquid chromatography results confirmed the production of a number of organic acids that contributed in the inhibition of the fungal growth. The study also proved the production of chitinase enzymes, which apparently altered the chitinous layer present in the cell wall of F. solani, causing disintegration of the fungal cells. It was also shown that encapsulation of E. faecium increased its viability in soil as compared with the free uncapsulated strain.
Anticancer redox action of gallium nanoparticles combined with a low dosage of γ-radiation against hepatocellular carcinoma in male rats
Authors: Abdalla Mohga S. , El-Mahdy El-Sayed M. , Mansour Somaya Z. , Elsonbaty Sawsan M. , Hussien Menna A.
Published: August 2022

Background and objective

Nanotechnology affords a new valuable field for the preparation of intrinsic nano anticancer drugs through green synthesis of plant active extracts supported with gallium nanoparticles (GaNPs) to provide us with a new Ga form of treatment with lower toxicity risk. The current study aimed at evaluation of a new GaNP form with grape seed extract as an anticancer agent against hepatocellular carcinoma (HCC) in rats. Moreover, the effect of the exposure to a low dose of γ-radiation on the treatment and prevention of tumor was studied.

Materials and methods

The cytotoxic effect was measured against the HepG2 tumor cell line. An experimental design was optimized using 80 Wistar male rats (120−150 g) divided into eight groups, with 10 rats each. The animals are administered with diethylnitrosamine to induce HCC and then orally administered with a dose of 38.5 mg/kg from the GaNPs in combination with the exposure of the total body to a low dose of γ-radiation (0.5 Gy).

Result and conclusion

The combination of GaNPs/γ-radiation demonstrated significant cytotoxicity against HepG2 cell line with an IC50 of 388.8 µg/ml. Moreover, the results indicated normal structures in the liver architecture, and the conventional biochemical assays showed significant depletion in lipid peroxide, alanine aminotransferase, and aspartate aminotransferase activities and creatinine levels. Additionally, there was a significant increase for the antioxidant state parameter in the form of a pronounced reduction of glutathione level. The ameliorative effect of the treatment was well appreciated by the histopathological alteration results. Therefore, it can be concluded that GaNPs/γ-radiation can serve as a good therapeutic agent for the treatment of HCC that ought to attract more studies.
A meta-analysis of prognostic factors in patients with left-sided pancreatic cancer
Authors: Fard Adeleh Hashemi , Sadeghi Ramin , Saffari Seyed Ehsan , Hashemi Fard Seyed Majid , Aliakbarian Mohsen
Published: August 2022

Background:

Patients with ductal adenocarcinoma of the body and tail of the pancreas usually remain asymptomatic until late in the course of the disease, and the survival of such patients depends on multiple factors, which may affect the therapeutic approach and patient survival. Hence, the aim of this study was to investigate such risk factors by pooling various available studies.

Methods:

A systematic review was conducted according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines between January 1, 2007, and December 31, 2016, using the following databases: Medline, Scopus, the Cochrane Library, and Google Scholar. Studies were selected according to the predesigned eligibility criteria, and information was extracted for demographics, clinical features, and survival outcomes. Data were pooled using fixed- or random-effects models.

Results:

Sixteen studies were included (5,660 patients) with a median age of 64.8 years and a median survival of 28.5 (range 13–38) months. Identified significant factors for overall survival were higher age (hazard ratio [HR] = 1.211), men (HR = 1.182), presence of lymph node metastasis (HR = 1.964), multivisceral resection (HR = 1.947), N stage (1 versus 0; HR = 1.601), surgical margin (R0 versus No R0; HR = 0.519) and tumor size (>3 cm; HR = 1.890).

Conclusion:

The pooled results of this study revealed several risk factors for overall survival in patients with left-sided pancreatic cancer.
Relationship between liver function tests & cardiovascular risk factors in stage 3-5 pre-dialysis chronic kidney disease
Authors: Selen Tamer , Akoglu Hadim , Agbaht Kemal
Published: August 2022

Background & objectives:

Cardiovascular disease (CVD) remains the leading cause of mortality among patients with chronic kidney disease (CKD). Liver function tests (LFTs) have emerged as markers of CVD risk in some population-based studies. Hence, in the present study the relation between LFTs and biochemical cardiovascular risk factors (CRFs) were evaluated in CKD patients.

Methods:

A total of 246 patients with stage 3-5 pre-dialysis CKD were enrolled. Demographics, LFTs [alanine aminotransferase (ALT), aspartate aminotransferase (AST) and gamma-glutamyltransferase (GGT)] and biochemical CRFs were recorded retrospectively. Glomerular filtration rate (GFR) was calculated using CKD-EPI equation.

Results:

ALT was positively correlated with GFR, albumin, triglyceride and 25-hydroxyvitamin D and negatively correlated with CRP and intact parathyroid hormone (iPTH); AST was positively correlated with GFR, albumin, high-density lipoprotein cholesterol (HDL-C) and 25-hydroxyvitamin D and negatively correlated with CRP and iPTH; GGT was positively correlated with GFR, CRP and triglyceride and negatively correlated with HDL-C. In diabetic patients, ALT correlated positively with GFR; AST correlated positively with GFR and HDL-C, but correlated negatively with iPTH. In the correlation analysis between GFR and CRF, GFR was positively correlated with albumin, triglyceride and 25-hydroxyvitamin D and negatively correlated with CRP, iPTH and albuminuria in both total study population and diabetic group. A partial correlation analysis revealed no correlation between LFTs and CRFs after being controlled for GFR.

Interpretation & conclusions:

The results of the present study suggest that the relationship between LFTs and biochemical CRFs seems to be a function of impaired GFR.
Papillary carcinoma of breast: An institutional overview of a rare histopathologic type
Authors: Gogoi Gayatri , Dowerah Swagata , Kashyap Akankshya S. , Terangpi Monika
Published: August 2022

Papillary carcinoma of the breast is a rare malignant tumor, constituting 1%–2% of all breast carcinomas in women. We studied a total of 6 cases of papillary cancer breast of which five were in female patients, and one was a male patient. Three were invasive papillary carcinoma while one was encapsulated papillary carcinoma without invasion, one was encapsulated papillary carcinoma with invasion and one was a solid type of papillary carcinoma. The median age of the patients was 45.5 years. All the tumors except one were seen in the left breast. Grossly, the size of the tumors ranged from 2 cm × 2 cm × 1.5 cm to as large as 6 cm × 10 cm × 4 cm. Three of the cases had positive axillary nodes. To conclude, papillary carcinoma is a rare tumor with a better prognosis as compared to Infiltrating duct carcinoma breast, and hence, it is important to be aware of the different subtypes and diagnostic pitfalls of this tumor to correctly diagnose it.
Imaging features of radiation-induced lung disease and its relationship with clinical and dosimetric factors in breast cancer patients
Authors: Yilmaz Ugur , Koylu Murat , Savas Recep , Alanyali Senem
Published: August 2022

Aim:

The aim is to extensively evaluate imaging features of radiation induced lung disease in breast cancer patients and to determine the relationship of imaging alterations with dosimetric parameters and patient related characteristics.

Materials and Methods:

A total of 76 breast cancer patients undergoing radiotherapy (RT) were studied retrospectively by case notes, treatment plans, dosimetric parameters, and chest computed tomography (CT) scans. Time intervals, that chest CT scans were acquired, were grouped as 1–6 months, 7–12 months, 13–18 months and more than 18 months after RT. Chest CTs (one or more for each patient) were assessed for the presence of ground glass opacity, septal thickening, consolidation/patchy pulmonary opacity/alveolar infiltrates, subpleural air cyst, air bronchogram, parenchymal bands, traction bronchiectasis, pleural/subpleural thickening and pulmonary volume loss. These alterations were scored by applying a system devised by Nishioka et al. Nishioka scores were analyzed for the relationship with clinical and dosimetric factors.

Statistical Analysis Used:

IBM SPSS Statistics for Windows, version 22.0 (IBM Corp., Armonk, N.Y., USA) was used to analyze data.

Results:

Median follow-up time was 49 months. Advanced age and aromatase inhibitor intake were correlated with higher Nishioka scores for 1–6 months’ period. However, both were found nonsignificant in multivariate analysis. Nishioka scores of CT scans acquired more than 12 months after RT were positively correlated with mean lung dose, V5, V20, V30, and V40. Receiver operating characteristic analysis revealed that V5 for ipsilateral lung was the most robust dosimetric parameter predicting chronic lung injury. V5 >41% indicates the development of radiological lung changes.

Conclusions:

Keeping V5 ≤41% for ipsilateral lung could provide avoiding chronic lung sequelae.
Incidence of thyroid cancer in Abu Dhabi, UAE: A registry-based study
Authors: Alseddeeqi Eiman , Altinoz Ajda , Oulhaj Abderrahim , Suliman Abubaker , Ahmed Luai A.
Published: August 2022

Context:

Thyroid cancer is the most common endocrine malignancy. It is ranked second among females of the Gulf Cooperation Council States and the sixth most common cancer among the United Arab Emirates population.

Aims:

We herein describe the incidence and distribution of different types of thyroid cancers and the demographic features of patients diagnosed with thyroid cancer in the Emirate of Abu Dhabi.

Settings and Design:

The study design was Abu Dhabi cancer registry and retrospective chart review.

Subjects and Methods:

This is a retrospective cancer registry description of patients with the different types of thyroid cancers diagnosed between January 2012 and December 2015 in the Emirate of Abu Dhabi. The incidence of thyroid cancer throughout the study period was calculated. Gender, age, ethnicity, and type of thyroid cancer were described.

Statistical Analysis Used:

Descriptive statistics of patients’ characteristics are reported as means (standard deviation) for continuous variables and total and relative frequencies (percentage) for categorical variables.

Results:

The incidence of thyroid cancer was found to increase annually, reaching 7.9 cases per 100,000 population in 2015. A total of 603 patients were diagnosed with thyroid cancer in the Emirate of Abu Dhabi from 2012 to 2015. Of these, 431 (71.5%) were women and 172 (28.5%) were men. The overall mean age at diagnosis was 40.2 years. Over a third of the patients were between 30 and 39 years. The classical papillary thyroid cancer type was found in 67.7% of cases.

Conclusions:

A substantial increase in thyroid cancer rates was found between 2012 and 2015. The majority of thyroid cancer cases were diagnosed in women between the ages of 30 and 39 years. Classical papillary thyroid cancer was the most common type.
Quantitative analysis of diffusion-weighted imaging and signal-to-noise ratio on the efficacy of albendazole liposome in the treatment of cerebral alveolar echinococcosis
Authors: Xing Hui , Du Xiaodan , Abulikemu Nuerbiyemu , Yang Jing , Gao Xin , Liu Jundi , Jiang Chunhui , Li Jingwen , Wang Jian
Published: August 2022

OBJECTIVE:

To investigate the feasibility of diffusion-weighted imaging (DWI) and signal-to-noise ratio (SNR) of lesions in evaluating the efficacy of albendazole liposomes in the treatment of cerebral alveolar echinococcosis (CAE).

MATERIALS AND METHODS:

Sixteen patients with CAE who met the inclusion criteria from April 2017 to December 2020 were enrolled. All patients underwent routine magnetic resonance sequence examination and DWI examination. The b-value were 1000 s/mm2 and 3000 s/mm2. The apparent diffusion coefficient (ADC) value and SNR of lesions before and after treatment were compared. The data of each group were statistically analyzed by Wilcoxon signed-rank sum test.

RESULTS:

After 1 year of treatment with albendazole liposomes, the SNR of lesions on T2WI sequence increased. There was a significant difference between the SNR of the same lesion before and after follow-up (P < 0.05). The ADC values of lesion parenchyma and edema area before and after treatment were compared. The difference between them was statistically significant in the both b values (ADC of parenchyma, P < 0.05; ADC of edema area, P < 0.001). Through binary linear classification, it was found that under the same b value, the effect of drugs on the edema area was more obvious than that on the parenchyma area; under different b values, the higher the b value, the higher the ability to evaluate the curative effect of drug therapy.

CONCLUSION:

Albendazole liposome is effective in the treatment of CAE, and long-term imaging follow-up of patients with CAE treated with albendazole liposome is necessary. When the change in conventional images is inapparent, the quantitative analysis of ADC value and SNR of lesions on T2WI can provide an objective basis for the evaluation of the curative effect of drug treatment in CAE.
Impact of fatty liver on acute pancreatitis severity and prognosis
Authors: Jiang Mingkuan , Zhang Miao , Zhang Lirong , Luo Lin , Chen Qiang
Published: August 2022

BACKGROUND:

Previous studies showed a significant correlation between fatty liver (FL) and acute pancreatitis (AP) onset, but the impact of FL on AP severity and prognosis remains uncertain. Therefore, we systematically searched existing publications in English and Chinese and conducted a meta-analysis to evaluate the effect of FL on AP severity and prognosis.

OBJECTIVE:

The purpose of this study was to analyze the correlation between FL and AP severity and prognosis.

MATERIALS AND METHODS:

All published controlled clinical studies on the relationship between FL and AP were identified by searching available electronic databases. We assessed the impact of FL disease on AP biochemical indicators, severity, and prognosis using pooled individual studies with an odds ratio (OR), standardized mean difference, and weighted mean difference.

RESULTS:

Thirteen clinical case − control studies met the meta-analysis entry criteria, and these studies included 6570 patients; among them, 2110 were patients with FL-relatedAP (FLAP) and 4460 were patients with non-FL-related AP (NFLAP). The meta-analysis results showed that the percentage of mild AP in FLAP was lower than that in NFLAP (OR = 0.32, P < 0.001), but the percentage of moderately severe AP (MSAP) and severe AP (SAP) in FLAP was higher than that in NFLAP (OR = 2.66 and 2.57, respectively, P < 0.001). The various prognostic indicators included the acute physiology and chronic health evaluation II score, systemic complications, local complications, total length of hospital stay, and mortality, which were all significantly higher in FLAP than in NFLAP (P < 0.05 for all).

CONCLUSION:

AP severity and prognosis were different between FLAP and NFLAP patients, and FL could be used as an independent risk factor for MSAP and SAP.
Manual Severity Evaluation Methods for Novel Coronavirus Pneumonia Based on Computed Tomography Imaging
Authors: Chen Qiang , Luo Lin
Published: August 2022

Computed tomography (CT) examination plays an indispensable role in the diagnosis of coronavirus disease-2019 (COVID-19). Many studies have evaluated the severity of COVID-19 based on CT images, with the severity of COVID-19 being evaluated either manually or by using artificial intelligence. In this review, the recently reported methods for manually evaluating COVID-19 severity based on CT images are summarized and divided into three categories: evaluation based on the extent of abnormalities; evaluation based on the characteristics of abnormalities; and evaluation based on both the extent and characteristics of abnormalities.
Q Fever as a Cause of Community-Acquired Pneumonia in French Guiana
Authors: Epelboin Loïc , Mahamat Aba , Bonifay Timothée , Demar Magalie , Abboud Philippe , Walter Gaëlle , Drogoul Anne-Sophie , Berlioz-Arthaud Alain , Nacher Mathieu , Raoult Didier , Djossou Félix , Eldin Carole
Published: August 2022

In French Guiana, community-acquired pneumonia (CAP) represents over 90% of Coxiella burnetii acute infections. Between 2004 and 2007, we reported that C. burnetii was responsible for 24.4% of the 131 CAP hospitalized in Cayenne. The main objective of the present study was to determine whether the prevalence of Q fever pneumonia remained at such high levels. The secondary objectives were to identify new clinical characteristics and risk factors for C. burnetii pneumonia. A retrospective case-control study was conducted on patients admitted in Cayenne Hospital, between 2009 and 2012. All patients with CAP were included. The diagnosis of acute Q fever relied on titers of phase II IgG ≥ 200 and/or IgM ≥ 50 or seroconversion between two serum samples. Patients with Q fever were compared with patients with non-C. burnetii CAP in bivariate and multivariate analyses. During the 5-year study, 275 patients with CAP were included. The etiology of CAP was identified in 54% of the patients. C. burnetii represented 38.5% (106/275; 95% CI: 31.2–45.9%). In multivariate analysis, living in Cayenne area, being aged 30–60 years, C-reactive protein (CRP) > 185 mg/L, and leukocyte count < 10 G/L were independently associated with Q fever. The prevalence of Q fever among CAP increased to 38.5%. This is the highest prevalence ever reported in the world. This high prevalence justifies the systematic use of doxycycline in addition to antipneumococcal antibiotic regimens.
Musculoskeletal Morbidity Among Adults Living With Spina Bifida and Cerebral Palsy
Authors: Haapala Heidi J. , Schmidt Mary , Lin Paul , Kamdar Neil , Mahmoudi Elham , Peterson Mark D.
Published: August 2022

Background: Individuals living with cerebral palsy (CP) or spina bifida (SB) are at heightened risk for chronic health conditions that may develop or be influenced by the impairment and/or the process of aging. Objectives: The objective of this study was to compare the incidence of and adjusted hazards for musculoskeletal (MSK) morbidities among adults living with and without CP or SB. Methods: A retrospective, longitudinal cohort study was conducted among adults living with (n = 15,302) CP or SB and without (n = 1,935,480) CP or SB. Incidence estimates of common MSK morbidities were compared at 4 years of enrollment. Survival models were used to quantify unadjusted and adjusted hazard ratios for incident MSK morbidities. The analyses were performed in 2019 to 2020. Results: Adults living with CP or SB had a higher 4-year incidence of any MSK morbidity (55.3% vs. 39.0%) as compared to adults without CP or SB, and differences were to a clinically meaningful extent. Fully adjusted survival models demonstrated that adults with CP or SB had a greater hazard for all MSK disorders; this ranged from hazard ratio (HR) 1.40 (95% CI, 1.33 to 1.48) for myalgia to HR 3.23 (95% CI, 3.09 to 3.38) for sarcopenia and weakness. Conclusion: Adults with CP or SB have a significantly higher incidence of and risk for common MSK morbidities as compared to adults without CP or SB. Efforts are needed to facilitate the development of improved clinical screening algorithms and early interventions to reduce risk of MSK disease onset/progression in these higher risk populations.
Dosing Variability and Clinical Outcomes of Oxybutynin: A Pediatric Cohort of Patients With Neurogenic Bladder
Authors: Malik Mahnoor F. , Randall Joseph Hogan , Campbell Jack G. , McLaughlin Matthew J. , Koenig Joel F.
Published: August 2022

Background: Despite the therapeutic advancements of the last several decades, neurogenic bladder remains a significant source of morbidity for patients with a spinal pathology. Oxybutynin is a mainstay of treatment in pediatric populations despite significant side effects and highly variable bioavailability. Objectives: To characterize the use of oxybutynin in a cohort of pediatric patients with neurogenic bladder. Methods: Retrospective data were collected of dosing, drug interactions, and urodynamics parameters in the 100 consecutive patients in a spinal differences clinic who had an appointment between October 7, 2015, and December 30, 2015. In addition to descriptive statistics, a linear regression model of oxybutynin dose versus age and sex was developed to examine the impact of age on dosing variability. Results: One hundred patients (52% female) with a median age of 6.8 years were included. The median daily dose of oxybutynin was 0.36 mg/kg (interquartile range, 0.28–0.54 mg/kg). Of the 48 patients with a recent urodynamics study, 13 had a detrusor leak point pressure (DLPP) greater than the typical cutoff of 40 cm H2O, indicating a need for management escalation. However, of these 13 patients, 38% were already on or exceeding oxybutynin’s maximum recommended dose. Conclusion: The wide dosing variability and high DLPPs despite maximal dosing indicate a need for further investigation of oxybutynin’s bioavailability in this population compared to its side effects and clinical outcomes. If variability in response to the medication is due to differences in bioavailability, then a precision-dosing model based on patient genomics could be developed for oxybutynin.
Differentials and distances in probabilistic coherence spaces
Authors: Ehrhard Thomas
Published: August 2022

In probabilistic coherence spaces, a denotational model of probabilistic
functional languages, morphisms are analytic and therefore smooth. We explore
two related applications of the corresponding derivatives. First we show how
derivatives allow to compute the expectation of execution time in the weak head
reduction of probabilistic PCF (pPCF). Next we apply a general notion of
"local" differential of morphisms to the proof of a Lipschitz property of these
morphisms allowing in turn to relate the observational distance on pPCF terms
to a distance the model is naturally equipped with. This suggests that
extending probabilistic programming languages with derivatives, in the spirit
of the differential lambda-calculus, could be quite meaningful.
Assessing the need for radiation protection measures in artisanal and small scale mining of tantalite in Oke-Ogun, Oyo State, Nigeria
Authors: Ajetunmobi A. E. , Musthapha A. O. , Okeyode I. C. , Gbadebo A. M. , Al-Azmi D. , David T. W.
Published: August 2022

There is concern that work scenarios on the tantalite mining sites in Oke-Ogun, Oyo State, Nigeria may cause occupational radiation exposure of workers due to enhanced concentrations of naturally occurring radionuclides in some process materials. A prior radiological assessment of the mining activities was carried out to determine if and which exposure scenarios may require radiation protection measures. Samples of the materials involved, comprising tantalite (tantalum ores), soil and waste rock were collected and analyzed for activity concentrations of 40K, 226Ra, 238U and 232Th using a hyper pure germanium detector gamma-ray spectrometer. Radon concentrations in the mines were also measured using a continuous radon monitor - Radon-Scout Plus (Sarad, GmbH). Activity concentrations of 40K are below 10 Bqg-1 in all the samples but all the tantalite samples contain more than 1 Bqg-1 of 226Ra and 238U. Hence tantalite is regarded as naturally occurring radioactive material (NORM) and the mining activity as a practice. The requirements for planned exposure situations apply to all the mining sites but, on the basis of graded approach, the optimum radiation protection measures vary from one mine to another, ranging from exemption to authorization. Exposures to radon in the underground mines pose the greatest radiological risks and portend the greatest need for regulatory control in the mining operations. The results further underscore the need to integrate radiation protection with the other health and safety measures in the mining sector.
Representaciones sociales de docentes noveles sobre la tutoría
Authors: Ortiz Blanco Cintia , Ortega Guerrero Juan Carlos , Casillas Alvarado Miguel Ángel
Published: August 2022

El propósito del estudio es comprender las representaciones sociales de docentes noveles de educación primaria sobre la tutoría, la tutoría formal e informal. Con un enfoque mixto y un estudio interpretativo se describe la teoría de las representaciones sociales como perspectiva teórica y metodológica. Con un cuestionario cualitativo aplicado a 257 noveles se exploraron las categorías información, campo de representación y actitud. Sobre la categoría información, los participantes asocian la tutoría con el apoyo, acompañamiento y guía que les ofrece un colega con funciones de tutor. Los noveles están más familiarizados con el término tutoría formal que con el de tutoría informal. 85% de los noveles han participado en el programa nacional de tutoría formal y 56% recibió tutoría informal en sus escuelas. Sobre la categoría actitud, pese a las diferentes experiencias reportadas por los noveles, prevalece una actitud favorable hacia la tutoría. con ligera preferencia hacia la tutoría informal. La modalidad es un informe de investigación.
Uso de las tic en la educación virtual del bachillerato: Un estudio de caso
Authors: Toala Vélez Frank , Cevallos Zambrano Doris Patricia
Published: August 2022

Las tecnologías de la información y la comunicación (TIC) cumplen actualmente un rol fundamental en el proceso enseñanza aprendizaje, más aún cuando la educación virtual, debido al COVID 19, ha aumentado significativamente convirtiéndose en la única manera de mantenerse en el sistema educativo durante el periodo de confinamiento.  El objetivo de la investigación fue analizar la incidencia del uso de las TIC’s en la educación virtual del bachillerato de la Unidad Educativa Fiscal Cinco de Junio, de la ciudad de Manta, en Ecuador.  Metodológicamente se define como una investigación descriptiva de campo, apoyado en el análisis documental mediante la revisión de referencias bibliográficas; se aplicó una encuesta a 45 docentes de la institución educativa en estudio, donde se obtuvieron resultados del proceso de educación virtual. Entre los resultados más destacados se pudo apreciar que las variables TIC y educación virtual están muy relacionadas ya que de la correlación de Pearson fue de 0,856; además el nivel de significancia es muy alto, siendo menor que 0,01 muestra una incidencia positiva de las Tecnologías de la Información y Comunicación con la Educación Virtual de estudiantes del bachillerato de la institución objeto de estudio. Se concluye que el uso de las TIC’S en la educación virtual del bachillerato motiva a la participación activa de los estudiantes y enriquece la práctica docente. Palabras clave: Tecnologías de la información y la comunicación, educación virtual, enseñanza, aprendizaje.
Importancia de los juegos tradicionales para fortalecer el desarrollo psicomotor de los niños de 3 a 5 años
Authors: García Ramirez Veronica Nataly , Tarazona Meza Anicia Katherine
Published: August 2022

El presente artículo es producto de una investigación, el cual tuvo como propósito dar a conocer la importancia de los juegos tradicionales para fortalecer el desarrollo psicomotor de los niños de 3 a 5 años. El estudio se llevó a cabo a través de una investigación acción desde la practica educativa en la que participaron 75 niños y 4 docentes de la “Unidad Educativa Magaly Masson del Valle Carrera” para ello fue necesario seguir cuatro etapas importantes: Diagnostico, planificación, ejecución y evaluación. En la etapa de diagnóstico se determinó que los niños presentan algunas debilidades psicomotrices, las docentes poco planifican acciones para potenciar el área, así como también no hacen uso de los juegos tradicionales para tal propósito. Esto condujo a realizar la planificación enmarcadas en los juegos tradicionales A través de la ejecución de las acciones y estrategias se observó un cambio significativo en los niños en el área motriz demostrando con ello que los juegos tradicionales son una estrategia lúdica importante dentro de hacer educativo.
Incorporating research training into undergraduate pharmacy courses: A case study from Australia
Authors: Ward Bernadette , Dickson-Swift Virginia , James Erica L. , Snow Pamela , Spark Joy , Verrinder Adrian
Published: August 2022

There is a dearth of research on the undergraduate research training provided to pharmacy students. We aimed to identify and provide examples of effective pedagogy in teaching research and evidence-based practice (EBP) to undergraduate pharmacy students. In conjunction with the professional competency standards for pharmacists, a review of the pharmacy workforce needs and the relevant pedagogical literature, a range of evidence-based approaches for selecting unit content, teaching and assessment strategies was identified. The authors reflect on the evidence and their multidisciplinary experiences in developing curriculum to demonstrate how pharmacy students can be engaged in deep learning rather than surface learning. Effective pedagogy in research training for pharmacy students will ultimately improve the quality of pharmacy education and the use of EBP principles in practice.
An IOT-Based System for Agriculture Monitoring
Authors: M Gautam Kalyani , Mahato Supriya , Sharma Hitakshi , Soni Deepak
Published: August 2022

A system is developed for agricultural field monitoring in IoT-based smart farming with the aid of sensors like light, humidity, temperature, soil moisture, etc. Farmers can keep an eye on the state of their fields from anywhere. Smart farming that is IoT-based is significantly more efficient than traditional farming. Agriculture has been practiced for centuries and is regarded as both a science and an art of plant cultivation. In today's world, agriculture must also maintain with the advancement of technology. IoT is crucial to smart agriculture. The necessary data regarding farm areas is provided by Internet of Things (IoT) sensors. The key benefit of IoT is the ability to monitor agriculture through the use of wireless sensor networks, which collect data from numerous sensors put at various locations and transmit it via wireless protocol. NodeMCU is the IoT system that powers smart agriculture. It has a DC motor, moisture sensor, temperature sensor, and humidity sensor. This system begins to measure the level of moisture and humidity. The sensors are used to detect the water level, and the system automatically begins watering if the level is below the range. The sensor works according to the change in temperature level. IoT also displays humidity and moisture level information along with date and time. You can also modify the temperature based on the crops that are grown.
RFID Implemented Library System
Authors: Pranav S  , Binny S  , Animol Thomas  , Georgy K Joseph  , Harish G Namboothiri
Published: August 2022

Libraries are important aspects of our life. These are important in providing or acquiring essential
knowledge about anything around us. Earlier Library system faced a lot of problems related to the
user accessing it using conventional methods. The RFID implementation on Library Management
system faced a lot of problems. The RFID implementations on library management helps to reduce
and sort out such issues that faced by conventional Library system.
Using RFID implementation, the database shows the availability of the book in the library so that the
student can search in the database and if available, they can collect book from the library. It helps to
handle the issue, renewal and return process for books using RFID tags implemented on it. Students
will also get notified about their status of due of books also.
Scratching the Surface: An Autoethnography to Begin to Understand and Address Illness Experience in Lice Infestation
Authors: Gray Jennifer
Published: August 2022

Though pediculosis, more commonly known as lice, is extremely common and has nothing to do with hygiene, misconceptions persist. Lice, constructed as a highly contagious illness, is more of a nuisance, with most contagion resulting from head-to-head contact, and 3% resulting from environmental causes; still, the condition tends to be associated with negative behavior like uncleanliness and neglect. There is very little study of it in the U.S. save for some “no nit policy” studies and almost none on the psychological or communicative impact on those affected. Through the analysis of pediculosis in my children, I detail an autoethnography of lice illness experience. Analysis suggests implications for the condition’s relationship to stigma, shame, misconceptions, victim blaming, and secrecy, as well as issues related to seeking social support, finding contradictory health information, special services costs, and giving over to health experts, particularly regarding framing. Stories thoughtfully examined and shared may aid in mitigating harmful frames and misconceptions as well as provide directions for helpful research. An examination of experience is a start in exploring this context from a communication perspective.
Possible (Theo)Linguistic Research with St. Nicholai Velimirovich’s Slovesnik as a Material
Authors: Levuškina Ružica
Published: August 2022

This paper describes the manuscript of St. Nicholai Velimirovich named Slovesnik which was published as a book in 1997. It was written in the fourth or at the beginning of the fifth decade of the 20th century and is addressed to nuns of certain Serbian monasteries — spiritual daughters of Bishop Nicholai. There is poetry and prose, there are documents, memorials, historical and hagiography texts, miniatures, drawings, etc. in the manuscript. All of that was written and drawn with warm paternal love. As for poetry, there are hagiography texts: Canon to the Most Holy Theotokos Slovesnica, Troparion and Kontakion to St. Georgios, the poem Zidanje Vraćevšnice [Building of Vraćevšnica] — written as an epic folk song, and lyrical songs. Almost in every text, Church Slavonic and contemporary Serbian interfere. In several places in the manuscript, the text in Church Slavonic is translated into Serbian next to the original, so we can find two parallel texts. Linguistically, this interference between two languages is interesting, not only in the lexical and translational sense, but also graphically: St. Bishop Nicholai used not only old letters in the text in Serbian, but also diacritical signs, especially ~ on the letter(s).
The basic directions of the (theo)linguistics research provided by the texts from this manuscript is the research in the fields of genre, translation, phonetic-phonology, lexical-semantic, derivation, stylistics, discourse, or text, and paremiology. The importance of the described edition for research in the field of pragmatics has to be especially emphasized. Pragmatics has a big research potential, as was said by Jean-Paul van Noppen — the founder of the term theolinguistics. He wrote that it is important “to delineate not only the semantics, i.e. what the words mean — what they describe, report, reflect and conjure up, but also the pragmatics, i.e. what the words do for people (which includes shaping their cognition)” (van Noppen 2011, 33). If we keep in mind who Saint Bishop Nicholai is addressing to in this manuscript (nuns, his spiritual daughters) — we have to state that this is an addressee who is very rarely in such a role. It is not easy to study communication in monasteries because the spiritual life of the monastic community is usually closed for observation, especially to linguists. Therefore, this edition has additional value as research material.
Deeper and more detailed linguistic research of the texts briefly described in this paper will show and open some other directions and approaches of (theo)linguistic research. By all these approaches, mentioned and not mentioned in this paper, we hope, that both theolinguistics and linguistics, in general, can be enriched, as well as, in the first place, studies of contemporary Serbian language (Serbistics).
The Serbian Chrysostom
Authors: Pehanich Edward
Published: August 2022

One of the greatest preachers and teachers of the Scripture is widely regarded to be St. John Chrysostom who lived and died over 1,600 years ago. We in America especially honor the memory of a man who lived and walked among us who has been called “The New Chrysostom” or “The Serbian Chrysostom” for his gift of preaching and teaching. St. Nicholai Velimirovich was born in 1880 in the small Serbian village of Lelich to pious Serbian Orthodox parents. He grew up in a home imbued with the life of the Orthodox Faith. His parents often interrupted their farm work for daily prayer and observed and celebrated all of the fasts and feastdays of the Church. His mother was often seen taking her little Nikola by the hand and walking three miles to the Chelije Monastery for prayer, Confession and Holy Communion. Later in life, St. Nicholai remembered these walks with his mother as being some of the most influential experiences of his life.
Tratamento homeopático em criança com transtorno do espectro autista (TEA): uma revisão bibliográfica
Authors: Rodrigues Kamila da Silva , Da Silva Elisabete Martins , Da Silva Natalia Delfino , Cavalcanti Élida Batista Vieira Sousa
Published: August 2022

O autismo é uma enfermidade caracterizada como uma desordem crônica do neurodesenvolvimento infantil, apresenta alguns sintomas comuns, mas a grande maioria das manifestações é individualizada e peculiar. Este trabalho é baseado em uma revisão bibliográfica enfocando o Transtorno de espectro autista (TEA) e a homeopatia como um tratamento benéfico que pode ser utilizado para proporcionar a essas crianças uma melhor qualidade de vida, à medida que esta patologia se mostra cada vez mais presente no mundo atual.
Effects of infrared radiation in the treatment of patients with knee osteoarthritis: a systematic review
Authors: Barry Mamadou Aliou , Pérez-Campos Eduardo , Navarro Luis Manuel Sánchez , Mayoral Laura Pérez Campos , Hernández-Huerta Teresa , Canseco Socorro Pina , Jerónimo Julia Hernández , Zarate Cuauhtémoc Matadamas
Published: August 2022

Background: osteoarthritis of the knee is a degenerative disease that affects different joints in the body. This pathology is characterized by very strong pain and loss of joint function in some cases. The infrared radiation contributes to the treatment of patients with osteoarthritis of the knee. Therefore, this treatment method can help to reduce pain and improve functional capacity. Objective: to compare the studies carried out on this topic to show the effects of infrared in the treatment of patients with osteoarthritis of the knee.

Method/ Data sources: to carry out this research, they were consulted in the following databases available on the internet: PubMed / Medline, Science direct, SciELO and Springer link. Selection criteria:3 randomized and 2 controlled articles were considered with a total sample of 260 subjects. All literatures were found in the period 2010-2020 and in the English and Spanish languages. Results: they found 871 studies in which 5 articles were selected with a total of 517 patients who meet the selection criteria results.

Limitations:  there is a lack of information in some databases on this topic of Knee Osteoarthritis. Conclusion: we concluded that infrared therapy has proven to be a reliable and effective method in the treatment of osteoarthritis, as it has shown a positive effect in reducing pain and inflammation of the knee.
Supersticiones infernales y carnicerías diabólicas: primer acercamiento a la escritura híbrida de Diego Muñoz Camargo en la Historia de Tlaxcala
Authors: Durán Escamilla Alejandra Gabriela
Published: August 2022

Un primer acercamiento a la Historia de Tlaxcala del cronista novohispano Diego Muñoz Camargo, nos permite conocer la mirada particular de un sujeto cultural del siglo XVI cuyo ejercicio letrado estuvo definido tanto por la tradición europea como por la indígena. Hijo de padre extremeño y madre tlaxcalteca, la condición bicultural de esta figura histórica determinó no sólo su manera de abordar el espacio virreinal a través de la escritura sino también, las formas de desenvolverse dentro de los círculos de poder e instituciones más importantes de la época.
Poetas nebulosos Menglong shiren (poeta nebuloso): su papel literario y político antes y después de Tiananmen (1989)
Authors: Marcos Lozano Mtra. Liliana
Published: August 2022

El periodo maoísta y varias décadas posteriores se vieron configuradas por un sin número de eventos políticos y sociales definidos por la ideología, la cual estaba basada en el pensamiento Marxista-leninista. El aspecto de la cultura fue un tema de mucha importancia en la China dinástica, en la que el arte dependía y atendía al poder imperial. Para el tiempo de Mao se esperaba que se reformulara arduamente el rol que debían tener los intelectuales y los artistas en la naciente Republica Popular, para que, cómo lo había postulado el mismo Mao, el arte sólo tuviera el fin de servir a la revolución, sin embargo, el arte y la cultura que tienen en su centro la expresión del sujeto, también podían constituir un punto de crítica al régimen y la figura de los líderes de la época, incluso a la misma figura de Mao. Esta nueva iniciativa tendió a ser cada vez más rígida hasta desembocar en la purga más grande del periodo: La Revolución Cultural.
Las Retromemorias y antifaces textuales en las narrativas autobiográficas de Rosario Castellanos y Tununa Mercado
Authors: Ippolito Fiordaliza
Published: August 2022

Narrar una autobiografía desde la narrativa de la infancia hace que la autobiografía retroceda a un pasado y buscar momentos específicos de nuestras vidas que marque momentos históricos. Esas memorias yo llamo retromemorias ya que ese pasado regresa con otro rostro textual en los que los recuerdos se mezclan con las memorias y aparecen ciertos silencios, pues desde allí existen huecos en el que el autor debe recorrer muchas veces a la ficción para poder llenar ciertos vacíos que se presentan en los espacios autobiográficos.
Gender Differential in the Intensity of Adoption of Oil Palm Processing Technology in South West,Nigeria
Authors: Bankole AS  , Arifalo SF
Published: August 2022

This research work investigated gender differential in the intensityof adoption of processing technology in South West, Nigeria. The primary data used for this research were collected using questionnaire. Multistage sampling method was used to pick 320, comprising of 160 each of both males and females oil palm processors.The information collected were analyzed using descriptive statistics and double hurdle model. The findings of the study revealed that many of the male (89.2%) and female (89.6%) processors had knowledge of improved technology of processing oil palm. Also,77.4% and 89.0% of the both male and female processors, respectively uses the digester, semi mechanized method of processing. The impact of extension services was not really felt in the study area as only few (4.3% and 2.2%) of the male and female processors respectively sourced their information through extension agents. The Double Hurdle Model results revealed that factors affecting adoption of the oil palm processing technology were education, access to finance, extension services, association, and experience of the female respondents while for the male respondents it includes education, extension services and experience. The outcome of the second hurdle model showed that factors affecting the intensity or adoption rate of technology among the female were extension services, level of education, access to finance and experience while for male respondents were level of education, extension services and memberships of association. Therefore, one can deduce that most of the processors in the area of study were not privileged to benefit from extension education and training. This might have negative impact in their enterprise and as well deny them in terms of information and innovative technologies to take good decisions that will increase their production level. Extension service is a paramount factor influencing adoption of technology and adoption rate of processing technology by both male and female genders. It is therefore recommended that government should provide extension services for processors in South west, Nigeria to increase level of acceptability of processing technology.
Status and Management Practices of Royal Bengal Tiger in Bangladesh National Zoo
Authors: Bahar F  , Zaber MAA  , Ahmed MJ  , Sahajee SR
Published: August 2022

The Royal Bengal Tiger (Pantheratigristigris) is the national animal of Bangladesh in addition to India. These most majestic mammalian cats are found in Sundarban mainly. It is a globally endangered and nationally critically endangered species that are conserved by Convention on International Trade in Endangered Species (CITES). The current study was carried out to establish the status is of tigers within the Bangladesh National Zoo. There are 9 tigers, including 5 males and four females, in the studytenure. The beef was supplied every day except Sunday at 8.47±2.36 kg beef and 0.35±0.14 kg liver per animal per day, whereas only 1.56±0.53 kg of broilerwas allowed on Sunday. The zoo experienced born of several cubs in the last 10 years and 75% of them aremale. However, unfortunately, some of the cubs were died due to cold stress, inbreeding, trypanosomiasis and renal failure. The zoo is a lovely place for breeding and conservationof endangered animals. But many problems are faced due to the lack of proper breeding policy. Housing and other management facilities were recorded well but not internationally standardized. Finally, it can be concluded that Bangladesh National Zoo is a good place for tiger conservation beyond some limitations.