bluuebunny/crossref_metadata_2025 huggingface dataset:
Tripotent Lgr5 stem cells in the posterior tongue generate non-taste lingual, taste bud and salivary gland cells
Authors: Verweij Laurens , Kim Seok-Young , Laskaris Dimitirios , Lin Lin , Son Gijs van , Ringnalda Femke , Winkel Chris , Slack Jay , Sanders Karin , Rheenen Jacco van , de Wetering Marc van , Clevers Hans
Published: August 2024

The circumvallate papillae (CVP) and foliate papillae (FoP) of the posterior tongue contain taste buds in close proximity to specialized salivary glands, known as von Ebner and minor salivary glands, respectively. The developmental relationship between taste buds and these salivary glands remains largely unexplored. Lineage tracing studies in mice have revealed that Lgr5 marks taste bud stem cells. Here, we report single-cell RNA sequencing of the entire CVP and FoP of mice, providing a transcriptional atlas of cells from tongue surface epithelium, taste buds and the associated salivary glands. We unveil a developmental trajectory in which taste buds, the associated salivary glands and the non-taste tongue surface epithelium originate from a common Lgr5+ cell. We confirm this tripotency at the clonal level in vitro, and with multicolor lineage tracing in vivo. Thus, CVP and FoP harbor chemosensory units composed of taste bud and salivary gland cells derived from the same parental Lgr5+ stem cell.
Gradient All-Nanostructured Aerogel Fibers for Enhanced Thermal Insulation and Mechanical Properties
Authors: Ye Dongdong , Fu Xiaotong , Si Lianmeng , Zhang Zhaoxin , Yang Tingting , Song Jianwei , Zhu Shuze
Published: August 2024

Lightweight, nanoporous aerogel fibers are crucial for personal thermal management and specialized heat protection. However, wet-spinning methods, exemplified by aramid aerogels, inevitably form a dense outer layer, significantly reducing the volume fraction of efficient thermal barrier nanovoids and limiting the development of ultimate thermal resistance in fibers. Herein, we develop a microfluidic spinning method to prepare gradient all-nanostructure aramid aerogel fibers (GAFs). Benefiting from the simultaneous shear alignment and diffusion dilution of a good solvent within the channels, the precursor gel fibers assemble into a structure with a sparse exterior and dense interior, which reverses during supercritical drying to form sheath and core layers with average pore diameters of 150 nm and 600 nm, respectively. Experiments and simulations reveal that the gradient nanostructure creates high interfacial thermal resistance at heat transfer interfaces, resulting in a GAF radial thermal conductivity as low as 0.0228 W m–1 K–1, far below that of air and wet-spun aerogel fibers. Moreover, GAF's unique nano-entangled network efficiently dissipates stress, achieving exceptionally high tensile strength (29.5 MPa) and fracture strain (39.2%). This work establishes a correlation between multiscale nanostructures and superlative performance, thereby expanding the scope of aerogel applications in intricate environments.
Single-molecule detection of transient dimerization of opioid receptors 1: Homodimers’ effect on signaling and internalization
Authors: Zhou Peng , Tsunoyama Taka A. , Kasai Rinshi S. , Hirosawa Koichiro M. , Kalay Ziya , Aladag Amine , Fujiwara Takahiro K. , Pigolotti Simone , Kusumi Akihiro
Published: August 2024

Opioid receptors (ORs) are critical for endogenous and synthetic analgesics. Their homodimerization is considered important for their pharmacological diversities, but whether they form homodimers remains controversial. Here, we established that the three classical ORs, mu-, kappa-, and delta-ORs (MOR, KOR, and DOR, respectively) undergo repeated transient (120-180 ms) homodimerizations every few seconds. This was done by using single-molecule imaging and developing theories for analyzing single-molecule colocalization data, which provide the key parameters, homodimer-monomer dissociation equilibrium constants and rate constants. Their 9-26 amino-acid C-terminal cytoplasmic domains, without sequence similarities, are involved in specific homodimerization, whereas the transmembrane domains provide less specific affinities. Using the membrane-permeable peptides mimicking the C-terminal homodimerization sequences which block homodimerizations, functions of monomers and homodimers were dissected. KOR and DOR homodimers, but not MOR homodimers, activate downstream G-proteins differently from monomers upon agonist addition, without influencing OR internalization. These findings could guide strategies to enhance OR-based analgesia.
Abstractive Text Summarisation using T5 Transformer Architecture with analysis
Authors: Bhukya Vasanth Kumar , Bhukya Umesh
Published: August 2024

Now a days, Text summarization has become important as the amount of text data available online grows at an exponential rate. Most of the text classification systems require going through a huge amount of data. In general, Producing exact and meaningful summaries of big texts is a time-consuming endeavour. Hence generating abstract summaries which retain the key information of the data and using it to train machine learning models will make these models space and time-efficient. Abstractive text summarization has been successful in moving from linear models to nonlinear neural network models using sparse models [1]. This success comes from the application of deep learning models on natural language processing tasks where these mod-els are capable of modeling the interrelating patterns in data without hand-crafted features. The Text to Text Transfer Transformer(T5) approach was used to investigate the text summarization problem, and the results showed that the Transfer Learning based model performed significantly better for abstractive text summarization than the Sequence to Sequence Recurrent Model.
District Certified Culturally Responsive Elementary Teachers and Their Mathematics Teaching Practices
Authors: Thomas Casedy
Published: August 2024

This case study examines how three elementary teachers, all certified by their school district in culturally responsive teaching (CRT) through professional development opportunities, implement mathematics teaching practices that support CRT and the development of learners’ cultural identities. Furthermore, this study examines the CRT certification process in the focal district and the structures that supported the teachers in their enactment of CRT. In the focal district, commitment to CRT has been identified by division leaders as one means to best serve historically marginalized learners in achieving academic excellence. Data were collected via interviews, questionnaires, observations, teacher journals, and other reportable data. The teachers’ CRT practices in mathematics fell into four large quadrants aligning with the work of Hammond’s (2015) Ready for Rigor framework. However, such practices were implemented in ways that exemplified particular tenets of CRT that are more thoroughly captured in seminal research-based literature; thus, a revised and adapted model was created to examine the CRT practices enacted in these elementary mathematics classrooms. The findings provide the field with a more informed understanding of what CRT can look like in elementary mathematics classrooms with teachers who have been certified in CRT from a district developed and applied certification model.
Malik Eşin Ölümü Halinde Birlikte Yaşanılan Konut Üzerinde Sağ Kalan Eşe Tanınan Özgüleme Hakkının, Malik Olmayan Eşe Boşanma Halinde De Tanınmasının ZGB Art. 121/III Kapsamında Değerlendirilmesi
Authors: Dağlıoğlu Duygu
Published: August 2024

Türk hukuku malik eşin ölümü halinde eşlerin birlikte yaşadığı konut üzerinde sağ kalan eşe kendi lehine birtakım taleplerde bulunma hakkı vermektedir. Bu talepler sağ kalan eşin bir ayni hakkın koruması ile eski yaşantısını devam ettirmesi amacına dayanmaktadır. Eşin kendi lehine ayni hak kurulmasına yönelik bu talepleri eşler arasındaki mal rejiminin tasfiyesi (TMK md. 240, 255, 279) ya da ölen eşin mirasının tasfiyesinden (TMK md. 652) kaynaklanabilir. Kaynağına göre bu taleplerin kullanım koşulları ve özgülemenin istenebileceği ayni hakların öncelik sıralaması değişmekle birlikte sağ kalan malik olmayan eş konutun kendisine mülkiyet, intifa hakkı veya oturma hakkı ile özgülenmesini talep edebilir. Talebin mirasçılar tarafından kabul edilip yerine getirilmesi mümkündür. Fakat mirasçıların bu talebi reddetmesi halinde eşin mahkemeye başvurarak lehine oturma hakkı kurulmasını talep etmesi gerekir.
Türk hukukundan farklı olarak İsviçre Medeni Kanunu (ZGB Art. 121/III)’nda oturma hakkı ile sınırlı olarak boşanma nedeniyle de malik olmayan eş lehine konutun özgülenmesi mümkündür Buna göre birlikte yaşanılan konut eşlerden birinin mülkiyetindeyse, diğer eş lehine onun talebi olmasa bile, tazminat ya da nafaka alacaklarına mahsup edilmek üzere, hakim sınırlı bir süre için oturma hakkı tanınmasına karar verebilir.
Türk Medeni Kanunu’nda malik olmayan eş için boşanma halinde böyle bir imkan bulunmamaktadır. Oysa ki eş ve varsa çocukların boşanmada da bir ayni hakla korunmak suretiyle eski yaşantısını devam ettirmekte faydaları vardır.
Bu çalışmada ZBG Art. 121/III ile İsviçre hukukunda malik olmayan eşe boşanma nedeniyle tanınan imkanın Türk hukukunda da düzenlenmesi üzerinde durulmaktadır. Bu kapsamda ayrıca ZGB Art. 121/III düzenlemesinin Türk hukukuna aynen ya da farklı biçimde alınıp alınamayacağı tartışılmaktadır.
A CONDIÇÃO DE SER PLANTONISTA: DESAFIOS E POSSIBILIDADES
Authors: Gomes Carla Cristina de Almeida , Dantas Jurema Barros , Dutra Adryssa Bringel
Published: August 2024

Esse trabalho é o resultado da análise da experiência da atuação prática dos alunos de psicologia no projeto Plantão Psicológico vinculado ao LAPFES do departamento de psicologia da UFC. Entendendo a prática do plantão como ferramenta importante para a formação do futuro terapeuta e abrangente em suas ações junto à comunidade, torna-se relevante a análise da experiência dos estudantes na condição de plantonistas. Utilizamos 79 relatos, produzidos entre 2018 e 2022. Optamos por um estudo exploratório qualitativo sob a perspectiva fenomenológica, com intuito de uma aproximação da realidade vivida para além da soma das menções dos fatos observados. Os resultados mostraram que o plantão é uma prática diferenciada da clínica tradicional, importante para a formação por contribuir com a experiência prática e a produção efetiva de ações de cuidado, fazendo pensar o fazer psicológico deslocado da rigidez técnica do contexto acadêmico e ainda, como ferramenta de política pública, que abraça diferentes realidades sociais e acolhe diversas demandas clínicas.
AVALIAÇÃO MACROSCÓPICA DO SISTEMA DIGESTÓRIO DE TEIÚS VIA ENDOSCOPIA DISGESTIVA FLEXÍVEL SOB CONTENÇÃO FARMACOLÓGICA
Authors: Marcos Vinícius de Souza  , Maria Larissa Bitencourt Vidal  , Alda Trivellato Lanna Neta  , Marco Aurélio Prata  , Carlos Leandro de Souza Mendes
Published: August 2024

O exame endoscópico do trato gastrointestinal é uma ferramenta auxiliar diagnóstica que vem sendo difundida na medicina veterinária, sendo ela subdivida por porções de estruturas para facilitar o acompanhamento e reconhecimento dos componentes avaliados, em suma maioria a avaliação é dos órgãos: esôfago, estômago, intestino delgado e intestino grosso. Essa técnica na medicina humana, corresponde a um método altamente aplicável, um componente indispensável do arsenal diagnóstico que na prática médica veterinária vem crescendo. Trata-se de uma inspeção dinâmica e em tempo real da superfície mucosa que reveste os órgãos, sendo possível verificar alterações nessas porções, como exemplo a presença de corpo estranho, inflamações, infecções e até alterações neoplásicas, sendo que as conclusões do endoscopista são baseadas na presença ou ausência de alterações visíveis no trajeto examinado. Objetivou-se avaliar as estruturas do trato digestório alto e baixo de teiús, visto que há poucos relatos na literatura sobre avaliação endoscópica flexível em animais da Ordem Squamata sob contenção farmacológica. O procedimento proposto mostrou-se plenamente eficaz na evidencia da composição estrutural da mucosa, evidenciando detalhes teciduais, diferenças morfológicas entre as porções, indicando que é um exame adequado para estudos diagnósticos do trato digestório de teiús, além de ser de fácil execução e com um período de tempo considerado rápido na avaliação em teiús adultos.
ENDOSCOPIA DIGESTIVA FLEXÍVEL EM RAPINANTES SOB CONTENÇÃO FÍSICA
Authors: Marcos Vinícius de Souza  , Maria Larissa Bitencourt Vidal  , Alda Trivellato Lanna Neta  , Marco Aurélio Prata  , Carlos Leandro de Souza Mendes
Published: August 2024

Os rapinantes são aves complexas e que podem ser acometidas por diversos problemas, inúmeras são as doenças que acometem o sistema digestório, tendo os agentes infecciosos como bacterias, fungos, parasitos e até mesmo vírus que afetam o trato digestivo das aves nativas e exóticas, sejam como agentes primários ou secundários. Neste contexto, existem formas de identificação, seja por avaliação clínica ou exames complementares como exames fecais, microbiológicos e hemogramas para direcionamento diagnóstico, no entanto, muita das vezes não são possíveis de determinar fidedignamente as alterações. A endoscopia do trato digestivo superior (esôfago, inglúvio – exceto em Strigiformes, proventrículo e ventrículo) pode ser uma técnica eficiente, pois verifica diretamente as estruturas epiteliais do sistema digestório facilitando a análise clínica, a coleta de materiais e até mesmo como método terapêutico em casos de corpo estranho, esta é realizada com um endoscópio flexível, dirigível e fino que possui na extremidade uma micro câmera digital. Objetivou-se avaliar as estruturas do trato digestivo superior, visto que há poucos relatos na literatura sobre avaliação endoscópica flexível em aves sob contenção física. O procedimento proposto mostrou-se plenamente eficaz na verificação das estruturas da mucosa dessas aves, que é uma técnica de fácil e rápida execução em aves de rapina adultas, fazendo com que essa metodologia seja aplicada a rotina de aves como método preventivo, diagnóstico e prognóstico nesses animais.
CONTENÇÃO FARMACOLÓGICA DE PECARI TAJACU (CETARTIODACTYLA: TAYASSUIDAE) COM TILETAMINA, ZOLAZEPAM, DETOMIDINA, ATROPINA E AZAPERONE, EM DOSES CALCULADAS POR EXTRAPOLAÇÃO ALOMÉTRICA INTERESPECÍFICA
Authors: Maria Larissa Bitencourt Vidal  , De Souza Marcos Vinícius , Trivellato Lanna Neta Alda , Prata Marco Aurélio , de Souza Mendes Carlos Leandro , De Freitas Espeschit Braga Isis , Lopes Azevedo Pedro , Queiroz Luz Hinário Líria
Published: August 2024

Objetivou-se avaliar a qualidade e segurança da contenção farmacológica de 13 exemplares de Pecari tajacu com a associação de tiletamina, zolazepam, detomidina, atropina e azaperone. As doses iniciais foram calculadas por meio de extrapolação alométrica interespecífica. Houve redução estatisticamente significativa (p<0,05) para os parâmetros de frequências cardíaca e respiratória, e temperatura corporal com o uso do protocolo. Todos os animais apresentaram sedação profunda com presença de miorrelaxamento total e ausência de resposta ao pinçamento. O início e fim da sedação profunda foram observados em média aos 18,00 ± 7,06 minutos e 119,77 ± 19,41 minutos, respectivamente. O protocolo avaliado é indicado para medicação pré-anestésica, transporte, exame físico, colheita de amostras de sangue, avaliação odontológica, microchipagem, colocação de brinco para identificação e outros procedimentos pouco invasivos de moderada duração em P. tajacu de cativeiro.
O USO DE CANABINOIDES NO TRATAMENTO DA EPILEPSIA
Authors: De Carvalho Viana Mayara , Rayane Azevedo Lopes  , De Oliveira Rocha Riethe
Published: August 2024

O presente trabalho apresenta uma pesquisa descritiva acerca do uso da planta Cannabis sativa como uma alternativa no tratamento da epilepsia frente a terapêutica farmacológica tradicional já existente. Popularmente conhecida como maconha é a droga de abuso mais utilizada em todo mundo, devido a isso um estigma foi criado sobre sua utilização como uma planta medicinal, porém sua eficácia bem como seus baixos efeitos adversos já foram comprovados por diversos estudos, mostrando como sua utilização pode ser eficaz. Apesar disso, seus mecanismos de atuação ainda não foram totalmente elucidados, necessitando de estudos que possam definir melhor o seu perfil farmacológico, gerando então uma nova linha de possibilidades na indústria farmacêutica voltadas para o tratamento de muitos pacientes que não respondem bem às opções já existentes. Com o avanço em pesquisas científicas voltadas para esses compostos presentes na planta, os canabinoides, que são os responsáveis pelos seus efeitos farmacologicamente ativos, a possibilidade de proporcionar o controle da doença para um maior leque de pacientes portadores de epilepsia poderá aumentar de forma significativa, além da possibilidade destes compostos atuarem no tratamento de diversas outras patologias como a esclerose múltipla, dentre muitas outras.
IMPACTO DO POSICIONAMENTO DA MARCA NA DECISÃO DE COMPRA: UM ESTUDO DE CASO NA INDÚSTRIA ALIMENTÍCIA
Authors: Souza Reginaldo Adriano de , Laudezir Cristino Rodrigues  , Rita de Cássia Martins de Oliveira Ventura  , Lilian Beatriz Ferreira Longo  , Anandy Kassis de Faria Alvin-Hannas
Published: August 2024

O estudo em questão investigou o impacto do posicionamento da marca de uma empresa do ramo alimentício na decisão de compra dos consumidores. Inicialmente, foi destacada a importância do planejamento estratégico e do marketing para o sucesso empresarial, ressaltando a necessidade de uma estratégia eficaz para se posicionar no mercado competitivo. A pesquisa adotou uma abordagem descritiva, utilizando um estudo de caso e questionários aplicados aos consumidores. A amostra foi composta por 97 participantes, visando avaliar a percepção dos consumidores em relação à marca, seus produtos e a influência desses fatores na decisão de compra. Os resultados revelaram que a marca em estudo é reconhecida pela maioria dos consumidores, com 90% deles afirmando ter conhecimento e consumir os produtos da empresa. O preço foi identificado como o principal fator influenciador na decisão de compra, seguido pelo sabor e pela facilidade de encontrar os produtos no mercado. A pesquisa também mostrou que a marca é amplamente disponível nos supermercados e mercearias locais. Apesar do reconhecimento positivo da marca e dos valores percebidos pelos consumidores, alguns desafios foram identificados. Cerca de metade dos entrevistados não consome os produtos com frequência, indicando uma lacuna na fidelização dos clientes. Além disso, a marca ainda é percebida por mais da metade dos entrevistados como equivalente às demais marcas do mercado, sugerindo a necessidade de um diferencial mais distintivo. Conclui-se que, embora a empresa tenha uma boa percepção de marca e valores reconhecidos pelo público-alvo, é necessário um esforço adicional para fortalecer a qualidade e o sabor dos produtos, visando torná-los verdadeiramente distintivos no mercado e impulsionar significativamente o consumo.
PLANTAS ALIMENTÍCIAS NÃO CONVENCIONAIS E INSEGURANÇA ALIMENTAR: PERSPECTIVA PARA POLÍTICAS PÚBLICAS E DESENVOLVIMENTO SUSTENTÁVEL
Authors: Sobral Santos Nazareth Rafaele
Published: August 2024

A insegurança alimentar continua sendo um desafio global, afetando milhões de pessoas em todo o mundo. Nesse contexto, as plantas alimentícias não convencionais (PANCs) têm emergido como uma potencial solução para melhorar a segurança alimentar. PANCs referem-se a espécies vegetais com valor nutricional e gastronômico, porém subutilizadas e pouco conhecidas em termos de cultivo e consumo em larga escala. Essas plantas oferecem uma grande variedade de nutrientes essenciais, antioxidantes e compostos bioativos, podendo desempenhar um papel crucial no combate à desnutrição e às deficiências nutricionais. Além disso, a diversificação das fontes alimentares com PANCs pode contribuir para a resiliência do sistema alimentar, reduzindo a dependência de culturas agrícolas tradicionais e promovendo a conservação da biodiversidade. Para alcançar o potencial das PANCs, é essencial o desenvolvimento de políticas públicas que incentivem a pesquisa, o cultivo e o consumo responsável dessas plantas através da criação de programas de educação alimentar e de conscientização sobre os benefícios nutricionais e ambientais das PANCs. Essas estratégias são fundamentais para aumentar sua aceitação e incorporação na dieta das populações, contribuindo para o desenvolvimento sustentável, através de políticas públicas bem planejadas e do engajamento da sociedade, desempenhando um papel fundamental na construção de um futuro alimentar mais saudável e equitativo.
BARRAGENS DE REJEITOS DE MINERAÇÃO: DESAFIOS E AVANÇOS NA PERSPECTIVA DA SUSTENTABILIDADE
Authors: Rodrigues Oliveira Patrocínio Fani , Bizawu Sébastien Kiwonghi , Moreira Silva Isabela
Published: August 2024

Nos últimos anos os desastres socioambientais causados pelo rompimento de barragens de rejeitos provocaram mortes e considerável impacto ambiental, demonstrando a fragilidade humana em gerenciar os empreendimentos minerários ao redor do mundo. O Brasil como um país de vocação mineral, possui centenas de barragens de rejeitos distribuídas pelo território nacional, sendo um desafio gerenciar esses empreendimentos de maneira segura, evitando rompimentos que possam causar danos à vida e ao meio ambiente.  Este artigo tem como objetivo analisar os desafios apresentados nos métodos construtivos das barragens, bem como a sua segurança, e pesquisar alternativas utilizadas na gestão dos rejeitos como forma de mitigar os impactos dessa atividade contribuindo para uma mineração sustentável. O estudo realizado demonstrou avanços no estabelecimento de leis que regulamentam o método construtivo das barragens, entendendo que essas construções fazem parte da prevenção e segurança. O gerenciamento da segurança das barragens por meio de cadastros e monitoramentos demonstrou boa estratégia para acompanhar as situações de riscos e danos potenciais associados. A pesquisa também constatou iniciativas para a utilização do rejeito de minério, na fabricação de diversos produtos como tijolos, telhas, escórias para estradas, vidros, entre outros. Considerando o estudo realizado, a construção regulamentada com garantia da segurança nas barragens, bem como a gestão adequada dos rejeitos de minério com maiores investimentos em pesquisas para seu aproveitamento em outros setores, atreladas a medidas de preservação e mitigação, demonstram que pode ser um caminho para minimizar os desafios no gerenciamento das barragens e avançar rumo a mineração sustentável.
Impact of Banking Performance Indicators on Share Price of Islamic Banks listed on GCC Stock Exchanges
Authors: Almonifi Yasser Saleh Ali , Bhosle Vasant
Published: August 2024

AbstractPurpose - This study aims to explore the impact of banking performance indicators on share price of Islamic banks listed on GCC stock exchanges.Method - The research methods related to quantitative approach are based on the data collected through the reports of 17 Islamic banks and 7 stock exchanges in GCC for the period from 2012 to 2021, where the panels approach tests and fixed effect model were used to measure performance.Result - The study findings indicate that return on assets has a negative and non-significant impact on the Islamic banks share price in the stock exchanges, also, the return on equity and price/earnings ratio have a non-significant positive impact on the banks share price, while there is a negative and significant impact between earnings per Share and the banks share price index.Implication - This research has significant administrative and applied implications. To gain a competitive advantage and achieving a greater market value, banks can further improve their investment performance. Furthermore, this research highlights the importance of developing Islamic banking performance and enhancing investment and financing strategies for stakeholders in Islamic banks, as well as in the financing and investment sector.Originality - This study is considered as one of the main studies contributing to the analysis of the impact of banking performance indicators on share price of Islamic banks listed on GCC stock exchanges.
Comparative Study on Disclosure of Islamic Social Reporting (ISR) Based on the ISR Index between Islamic Banking in Asia and Africa
Authors: Mariana Anita , Warno Warno , Rahmiyanti Firdha
Published: August 2024

Purpose - This study aims to compare the level of disclosure of Islamic Social Reporting between Islamic banking in Asia and Islamic banking in Africa using the ISR index approach.  Method - The data analysis in this study used content analysis. The sample in the study was 18 Islamic Commercial Banks with purposive sampling method.Result - The results of the study show that there are differences in the implementation of social performance of Islamic banking in Asia and Africa. This is proven by the results of the Mann Whitney test with a sig value of 0.001 greater than α = 5%. There is some evidence that of all Islamic banks, both Asian and African, none has yet achieved 100% (one hundred percent) implementation and disclosure of the ISR Index.Implication - This research uses secondary data in the form of annual reports and annual financial reports on the respective official websites of Islamic Commercial Banks in Asia and Africa during the 2012-2020 period.Originality- Further research is expected to be able to use or add variables and increase the research sample so as to obtain results that better describe the actual situation.
Oil Price Volatility And Macroeconomics, Does It Affect The Performance Of Islamic Stocks In The Jakarta Islamic Index?
Authors: Baroroh Hilmy , Azka Mohammad Shadam Taqiyyuddin , Afifah Sabrina Nur
Published: August 2024

Purpose - This study aims to determine the effect of world crude oil prices and macroeconomics on the performance of Islamic stocks in the Jakarta Islamic Index (JII).Method - The research approach uses quantitative with the Autoregressive Distributed Lag (ARDL) method to analyze the short-term and long-term influence. The research sample was taken from as many as 29 companies included in the JII Index with the observation period from 2016-2022.Result - The results of this study show that the relationship between crude oil prices and Islamic stock performance has a significant negative effect. The rupiah exchange rate has a significant negative effect on the performance of Islamic stocks. Central bank interest rates, in this case using the BI Rate, have a significant positive effect on the performance of Islamic stocks. Inflation has a significant positive effect on the performance of Islamic stocks.   Implication - This study uses Islamic stock performance data from each company listed in the Jakarta Islamic Index and macroeconomic data obtained based on bank indonesia reports and crude oil prices derived from WTI crude oil prices.  Originality- This study looks at the short-term and long-term effects of crude oil prices and macroeconomics on the performance of Islamic stocks in the JII. The ARDL method is used to provide accurate results.
Statistical analysis of ESP defects detected during the robotization of control operations
Authors:   Ufa State Petroleum Technological University, Ufa, Russia, Gindullin I.I.
Published: August 2024

This article presents the prospects for using statistical analysis of defects in parts of electric centrifugal pumps (ECP) installations, which are detected during cleaning, evaluation and flaw detection operations in a specialized robotic autonomous diagnostic module. A comprehensive statistical analysis was carried out using methods of descriptive statistics, regression analysis, time series analysis and multidimensional methods based on a representative database of ESP failures. The analysis of the regression analysis results revealed a significant influence of temperature and pressure on the probability of defects in the ESP parts. Using the obtained result and data on operating modes, a prototype of an expert-advising system has been implemented that generates recommendations for optimizing cleaning, evaluation and flaw detection modes, indicating the most likely types of defects. The implementation of the proposed recommendations ensures a reduction in time and cost costs for preparatory operations, weight and dimensional control, increased accuracy of flaw detection and, as a result, increased reliability of the operation of the ESP, reduced operating costs of oil and gas producing enterprises. The conducted research demonstrates a high potential for the application of modern statistical methods for solving practical problems in the oil and gas industry.
Una propuesta hermenéutica para pensar los roles de la mujer en la Iglesia: el caso de Mujeres Iglesia y la figura de Prisca en el Nuevo Testamento
Authors: Salazar Juan
Published: August 2024

La agrupación chilena Mujeres Iglesia (MI), entre otros movimientos feministas eclesiales, han tratado de responder a la pregunta por el lugar de la mujer en la comunidad católica contemporánea, en búsqueda de mayor equidad y justicia. Para ello, MI propone buscar fuentes de inspiración en los textos bíblicos. Este artículo analiza las características del movimiento chileno y los roles que ejerce una de las mujeres miembro de las primeras asambleas de seguidores de Jesús: Prisca. Revisitaremos el rol dinámico de la mujer en las asambleas del cristianismo primitivo y las sociedades que les rodean, desde la caracterización que ofrecen algunos textos del Nuevo Testamento (las cartas de Pablo y el libro de los Hechos de los Apóstoles). A partir de esta propuesta hermenéutica, podemos afirmar que Prisca es una figura iluminadora para la comprensión del liderazgo de las mujeres en la iglesia, dado el carácter multifacético de su autoridad, principalmente, en tanto colaboradora, es decir, mujer líder de las comunidades de seguidores de Jesús.
In Silico Molecular Docking and Molecular Dynamics Analysis of Antimicrobial Triazole Derivatives: Insights from Synthesis, Computational and In Vitro Studies
Authors: Sharma Shikha , Kumawat Naveen , N. Mali Suraj , Meghani Monika , Kumar Nitin , Mathew Bijo , Kumar Sunil
Published: August 2024

Introduction:

In the ongoing fight against bacterial resistance to antibiotics, this study
focuses on synthesizing and evaluating 1,2,4-triazole derivatives to explore their potential as
new antibacterial agents. 1,2,4-Triazole compounds are promising drug candidates with a wide
range of therapeutic effects, including pain relief, antiseptic, antimicrobial, antioxidant, antiurease,
anti-inflammatory, diuretic, anticancer, anticonvulsant, antidiabetic, and antimigraine properties.

Method:

The structures of all the synthesized compounds were identified using their
physicochemical properties and spectral techniques, such as IR and NMR. These compounds
were then evaluated in molecular docking studies against antimicrobial activity in vitro and
further supported by molecular dynamics studies.

Result:

Compound 7, featuring a 6-chloro group on the phenyl ring, emerged as the most
effective against Gram-positive S. aureus compared to the standard antibiotic ciprofloxacin.
Docking studies revealed high and comparable affinities for all ten ligands, with compounds 4
and 6 showing the best-docked activity against Penicillin Acylase mutants. Further, compounds
6 and 10 displayed significant affinity against D-alanine-D-alanine ligase (DDL) from Yersinia
pestis during 100 ns MD simulation.

Conclusion:

Notably, compound 7 demonstrated the highest binding score to the 5C1P protein,
suggesting its potential as a lead molecule for the development of potent and safer antimicrobial
agents. This research contributes valuable insights into addressing the escalating challenge of
bacterial resistance.
Challenges of Diagnosis and Management of Burning Mouth Syndrome: A Literature Review
Authors: Lígia Martins Almeida Nara , Moraes Oliveira Gabriela , Ferreira Santos Carlos , Soares Lara Vanessa , Lopes Cardoso Camila
Published: August 2024

Background:

Burning Mouth Syndrome (BMS) is defined as an idiopathic orofacial
pain with recurrent intraoral burning. It mainly affects middle-aged women in peri- or post-menopause
and the elderly, without any identifiable causative lesions and with or without somatosensory
alterations. BMS has a complex pathogenesis involving psychogenic factors and deregulated peripheral
and central pain, and there is no standard treatment protocol, making its diagnosis and management
challenges.

Objective:

This study was to carry out a review literature on BMS, addressing its identification
and therapeutic possibilities.

Methods:

Review articles and randomized controlled clinical studies whose full text was available,
published between 2017 and 2022 in national and international journals, from PubMed and
SCIELO databases, WHO manuals and books, were collected. As a search strategy, the keywords
“burning mouth syndrome”, “treatment” and “diagnosis” were used, totaling 42 papers. Of these,
after applying the exclusion criteria, 34 articles were selected.

Results:

Studies indicate that a comprehensive and thorough anamnesis is essential to exclude secondary
factors leading to the correct diagnosis of BMS. In addition, a comprehensive anamnesis
directs the best management considering a combination of neuropathic and palliative therapies,
which aim to control, eliminate and/or minimize painful symptoms, treating the patient in an individualized
way and not the disease itself, since this pathology has no cure.

Conclusion:

Considering the impact of BMS on quality of life, further studies are needed to expand
diagnostic and treatment strategies, aiming to complement existing pharmacological and
non-pharmacological treatments, observing the influence that biopsychosocial and neurophysiological
mechanisms have on this syndrome.
IDENTIFIKASI FAKTOR PENENTU PROFITABILITAS BPR DI PROVINSI NUSA TENGGARA TIMUR (NTT)
Authors: Saputri Kristiani Hilda , Al Muizzuddin Fazaalloh
Published: August 2024

This study aims to determine the effect of CAR, LDR, and NPL on the profitability of Rural Banks in East Nusa Tenggara Province for the period 2017 – 2022. The purpose of this study is to determine the effect of capital adequacy, credit risk, liquidity risk, and operating costs on BPR profitability with a research sample of 11 banks. The research method used in this research is purposive sampling method. The data analysis technique uses panel data regression with a random effect model.
ANALISIS KOMPARASI PENGARUH RISIKO SISTEMATIS TERHADAP RETURN SAHAM SEKTORAL DI INDONESIA PADA MASA PERANG RUSIA-UKRAINA DAN KRISIS PROPERTI CHINA
Authors: Pradani Amaretta Hanindya , David Kaluge
Published: August 2024

The study aimed to find out a comparison of the influence of systematic risk on 11 sectoral stock returns in the time of the Russian-Ukrainian war and the Chinese property crisis. This study uses quantitative research methods with linear regression analysis tools using dummy variables. The data used in this study are secondary data in the form of time series with weekly time periods from 2021 to 2023. The study found that systematic risk values during the Russian-Ukrainian war and the Chinese property crisis were lower than in normal times. In wartime systematic risk had a significant impact only on the stock returns of the primary consumer goods sector. Meanwhile, during the Chinese property crisis systematic risk did not have a significant effect on all sectoral stock returns. In addition, in normal times systematic risks do not have a significant effect on the return of shares of the technology sector as well as property and real estate.
PENGARUH SISTEM LAYANAN JEMPUT ZAKAT, LAYANAN VIA TRANSFER, LAYANAN KONTER ZAKAT DAN KUALITAS PELAYANAN TERHADAP PREFERENSI MUZAKKI MEMBAYAR ZAKAT DI BAZNAS KOTA MOJOKERTO
Authors: Sutiyani Dina , Galuh Ajeng Kartika
Published: August 2024

This study aims to determine the effect of the zakat pick-up service system, transfer service, zakat counter service, and service quality on the preferences of muzakki to pay zakat at BAZNAS Mojokerto City. The approach used in this research is a quantitative approach. The sampling method or respondents from this research is opening 98 muzakki. The data used is taken through the distribution of questionnaires. This study uses a binomial logistic regression analysis technique using a test tool, namely the SPSS 22.0 program. The results showed that simultaneously, the variables of zakat pick-up service (X1), zakat transfer service (X2), zakat counter service (X3) and service quality (X4) had a significant effect on the preference of muzakki to pay zakat (Y). Partially, each variable of zakat pick-up service, zakat transfer service, zakat counter service and service quality has a significant effect on the preferences of muzakki to pay zakat in BAZNAS of Mojokerto City.
PEMBERDAYAAN MASYARAKAT MELALUI PROGRAM PONOROGO CERDAS (STUDI PADA MUSTAHIQ BAZNAS PONOROGO)
Authors: Ayu Putri Arina , Muttaqin Aminullah Achmad
Published: August 2024

Zakat funds have a function to distribute their funds to community groups who are unable or mustahik in community empowerment or only consumptive funds are given for direct consumption. Zakat funds can also be channeled for education costs in the form of scholarships for poor people. This research was conducted in the district with the aim of researching community empowerment through the Education scholarship program at Baznas Ponorogo Regency. In this study using a qualitative approach. This research is an activity that must carry out a survey in the field to identify information and conditions that are carried out there. For this reason, the right approach is qualitative because it can reveal various information with careful and meaningful description-analysis, providing complex details about phenomena that are difficult to express. The result of this research is the Smart Ponorogo Program launched by BAZNAS Ponorogo in order to improve community empowerment so that the quality of life of the community becomes better and runs effectively, this information is supported by several informants. Behind this success, there are obstacles that are still a lot of lack of public understanding of zakat in BAZNAS, and the lack of public knowledge about the management of zakat funds at BAZNAS. There are also factors that support this program to run smoothly because of the collaboration between parents and schools as well as the cooperation of scholarship recipients
PENGARUH KEPERCAYAAN, KEMUDAHAN, RELIGIUSITAS DAN PERSEPSI RISIKO TERHADAP KEPUTUSAN PEMBELIAN MENGGUNAKAN SPAYLATER
Authors: Wulan Dary Riszha , Pudjihardjo Muhammad
Published: August 2024

The development of globalization has an impact on human life by bringing changes to human life. various fields today. One of them is the field of technology and information that is developing and cannot be separated from the internet. Many marketplaces have sprung up in Indonesia, this research focuses on the shopee marketplace. Shopee is the most visited marketplace in Indonesia. Shopee provides various payment methods, one of which is Spaylater. The Spaylater system is the same as a credit card in that it provides loans to its users. The younger generation, namely Generation Z, currently dominates internet users in Indonesia. They mostly use it for social media or online shopping. The purpose of this study was to determine the effect of trust, convenience, religiosity and risk perception on purchasing decisions using Spaylater. This study uses a descriptive quantitative approach with multiple linear regression analysis. The sampling method used is non-probability sampling with purposive sampling technique. The sample of the population is 125 respondents from generation Z Muslims in Indonesia. The results obtained that trust, ease of use, religiosity and perceived risk together have a significant effect on purchasing decisions using Spaylater.
ANALISIS FAKTOR – FAKTOR YANG MEMPENGARUHI KEPUTUSAN MENUNAIKAN ZAKAT PROFESI (STUDI KASUS PADA GENERASI MILENIAL KOTA TANGERANG)
Authors: Tabhina Rafa Kayla , Ekawaty Marlina
Published: August 2024

Indonesia is a country with a majority Muslim population and still experiencing poverty. One of the efforts to eradicate poverty in Islam is through zakat, especially professional zakat, which has considerable potential because it can be paid monthly or annually. The millennial generation is also said to be able to help optimize the zakat collection in Indonesia. Tangerang City is one of the regions in Indonesia called the City of Akhlakul Karimah. Hence zakat is the right step to eradicate poverty, especially from professional zakat, because Tangerang City is dominated by the millennial generation and has a fairly high Regional Minimum Wage (UMR) level. Therefore, this study aims to analyze the effect of zakat knowledge, social environment, and income on the decision to pay professional zakat for the millennial generation of Tangerang City. The approach used in this study is a quantitative approach through logistic regression analysis. The results showed that the social environment variable significantly affected the decisions of the millennial generation in Tangerang City in paying professional zakat. In contrast, there is no significant effect of the variable knowledge of zakat and income on the decisions of the millennial generation in Tangerang City in paying professional zakat.
PENGARUH LITERASI KEUANGAN SYARIAH, KEPERCAYAAN, DAN PELAYANAN SYARIAH TERHADAP PREFERENSI TABUNGAN BSI
Authors: Putri Putri Heriska
Published: August 2024

Sharia savings products are one of the instruments used by the public to be a place to store assets. BSI is one of the largest Islamic banks in Indonesia that provides many sharia savings product services. The purpose of this study was to determinate how the influence of sharia literacy, customer trust, and sharia banking services on the preference for using BSI sharia savings products. This study uses quantitative methods with multiple linear regression analysis. This study uses primary data in the form of questionnaires and secondary data obtained from the result of literature studies an journals. This research was conducted at BSI KC Malang Sutoyo with a total of 100 respondents. In this study, the tools used to manage data were using IBM SPSS Ver. 23. The result of this study found that Islamic financial literacy, cutomer trust, and Islamic banking services both partially and simultaneously affect the preference for using sharia savings products at BSI KC Mlang Sutoyo.
NIAT WAKAF TUNAI ONLINE PADA MAHASISWA EKONOMI ISLAM
Authors: Hanna  , Widiyanti Dwi Retno
Published: August 2024

Indonesia with a majority Muslim community makes the potential for cash waqf very large. According to the National Committee for Islamic Economics and Finance (KNEKS), the potential for cash waqf could reach IDR 180 trillion, but the realization of waqf is still far below the existing potential. In general, the practice of waqf can help the socio-economic development of the Muslim community and distribute wealth among the community because waqf is intended to fund and maintain Islamic institutions such as madrasas, schools, universities and other public services. The research was conducted with the aim of knowing the effect of income, knowledge, trust, and convenience of students on students' intentions to do cash waqf at online waqf institutions. This study uses a descriptive quantitative approach with logistic regression analysis method. The sampling method used was Non-Probability sampling with Purposive Sampling Technique, and found 176 according to Isaac and Michael's formula from the total population of Islamic Economics Students from the batch of 2015 until 2021. From the R-Square test, it is known that the independent variables in the study can explain 64.2% of the related variables and the rest can be explained by variables outside of the study. In addition, the results of this study indicate that the convenience variable is significant to the students' intention to perform waqf through money. While the variables of income, knowledge, and trust have no significant effect on students' intentions in conducting cash waqf through online waqf institutions.
ANALISIS PENGARUH ZAKAT DAN INVESTASI TERHADAP PENDAPATAN PER KAPITA 2020-2021
Authors: Muhtadin Widyoko
Published: August 2024

Income per capita is the average annual income of the community. Community welfare can be viewed through the per capita income of the community in a certain area. From a macroeconomic point of view, investment is able to drive growth rather than people's per capita income. This is done by adding gross fixed capital in a region until it reaches the stage of full employment. In addition to investment, zakat from an Islamic economic perspective is also felt to be able to increase people's welfare. Zakat is a socio-economic instrument that creates prosperity through an equal distribution process. Central Java as one of the provinces on the island of Java has the lowest per capita income on the island of Java. This research was conducted to review the effect of investment and zakat in Central Java on income per capita. Through a time series research process that takes 2020-2021 and also a cross section with a sample of 32 cities and regencies, the aim is to review the effect of zakat and investment on each region in Central Java. Apart from the zakat variable through the micro dimension of NZI and the macro dimension of NZI and investment, this research uses a control variable in the form of government social assistance (Bansos) originating from the APBD of each region in Central Java. The results of this study indicate that simultaneously the investment variable, zakat which is divided into the micro dimension NZI and the macro dimension NZI, and also the control variable in the form of social assistance has a significant influence on income per capita in Central Java in 2020-2021. From this, investment and zakat are considered quite effective in increasing the per capita income of the people of Central Java.
Keywords: IZN Micro Dimensions, IZN Macro Dimensions, Investment, Social Funding.
WAKAF OLEH PUTRI KETURUNAN KESULTANAN GUNUNG TABUR (Studi Kasus pada Wakaf Masjid Al-Hijrah Gunung Tabur, Berau Kalimantan Timur)
Authors: Ariffiatin Dina Mely , Widiyanti Dwi Retno
Published: August 2024

Management of waqf assets carried out by professional nazirs following their objectives, functions, and uses can make waqf a potential Islamic institution that is useful in strengthening the people's economy. The role of women in waqf has been seen since the time of the Prophet ﷺ. One of the women who made waqf was Hajjah Aji Putri Nural Ayani who was a descendant of the Gunung Tabur sultanate and donated her inheritance in the form of land to build a mosque. The purpose of writing this research is to find out the practice of waqf by the daughter of the descendants of the Sultanate of Mount Tabur and to find out the role of mosque waqf on Mount Tabur for the Socio-Economy of the community. This study uses a qualitative approach to the historical approach. The results of the research findings obtained that the daughter donated land to build the Al-Hijrah mosque in 1991 and the construction of the mosque was assisted by the Pancasila Muslim Amal Bakti Foundation. This mosque land waqf has a role in the fields of worship, education, social, economic, and political. There are also obstacles and challenges in the form of developing waqf assets, waqf archives, and managing human resources faced in maintaining the land waqf of the Al-Hijrah mosque.