Assessment of the effect of nutrition optimization on macronutrient metabolism and general blood analysis in men under conditions of intense mental labor
Authors:   Federal State Budgetary Educational Institution of Higher Education «Privolzhsky Research Medical Universi - ty» of the Ministry of Health of the Russian Federation, Nizhny Novgorod, Russia, Rakhmanov R. S. , Bogomolova E. S. ,   Federal State Budgetary Educational Institution of Higher Education «Privolzhsky Research Medical Universi - ty» of the Ministry of Health of the Russian Federation, Nizhny Novgorod, Russia, Narutdinov D. A. ,   Federal State Budgetary Educational Institution of Higher Education «Krasnoyarsk State Medical University named after. prof. V. F. Voino-Yasenetsky» Ministry of Health of the Russian Federation, Krasnoyarsk, Russia, Razgulin S. A. ,   Federal State Budgetary Educational Institution of Higher Education «Privolzhsky Research Medical Universi - ty» of the Ministry of Health of the Russian Federation, Nizhny Novgorod, Russia
Published: January 2025

The mechanisms of stress on the body are manifested by stress on the metabolism of food
substances. The aim is to evaluate the impact of nutrition optimization on the indicators of macronutrient metabolism and general blood analysis of men in conditions of strenuous mental work. Blood
counts were analyzed in 60 men. Persons of the main group (n = 30) took the product in the composition
of plant components of 10 g for 21 days. In the initial state, blood samples were taken on days
22 and 32, general clinical and biochemical blood tests were performed. Protein metabolism was characterized by total protein and creatinine; lipid — triglycerides, total cholesterol, high and low density lipoproteins; carbohydrate — glucose. In the presence of harmful working conditions (class 3.3), signs
of macrocytic hypochromic anemia were revealed according to the intensity of the labor process; triglyceridemia in 18.4 %, hypercholysterinemia in 59.2 %, elevated high-density lipoproteins in 90.3 %,
reduced high-density lipoproteins in 22.6 %. As a result of additional intake of nutrients (proteins, fats and carbohydrates in the amount of 0.84–2.22 %, vitamins — 0.8–7.4 %, minerals — 0.2–5.15 %,
dietary fiber up to 6.5 % of the daily requirement), there was a decrease in total cholesterol in 23.4 %, triglycerides in 10.0 %, low-density lipoproteins in 20.1 %, lipid atherogenicity in 50.0 %. An increase
in erythrocytes, hemoglobin and hematocrit was noted, as well as a decrease in the proportion of
people with an increased average erythrocyte volume. The average concentration of hemoglobin in
the erythrocyte initially did not correspond to the norm in 30.0 %, at the end of the observation — in
10.0 %. The proportion of individuals with higher than normal eosinophil counts before and after taking
nutrients was 20.0 % and 10.0 %, monocytes — 43.3 % and 26.7 %. In the comparison group,
high-density lipoproteins decreased, and blood atherogenicity increased in 32.1 %. The achieved positive
effect proves the effect of taking nutrients on improving the nutrition of organs and tissues of the
body, reducing signs of stress and the risk of developing cardiovascular diseases.