bluuebunny/crossref_metadata_2025 huggingface dataset:
Investigating confounders of the association between survival and adjuvant radiation therapy after breast conserving surgery in a sample of elderly breast Cancer patients in Appalachia
Authors: Camacho Fabian , Anderson Roger , Kimmick Gretchen
Published: December 2019

Background

To explain the association between adjuvant radiation therapy after breast conserving surgery (BCS RT) and overall survival (OS) by quantifying bias due to confounding in a sample of elderly breast cancer beneficiaries in a multi-state region of Appalachia.

Methods

We used Medicare claims linked registry data for fee-for-service beneficiaries with AJCC stage I-III, treated with BCS, and diagnosed from 2006 to 2008 in Appalachian counties of Kentucky, Ohio, North Carolina, and Pennsylvania. Confounders of BCS RT included age, rurality, regional SES, access to radiation facilities, marital status, Charlson comorbidity, Medicaid dual status, institutionalization, tumor characteristics, and surgical facility characteristics. Adjusted percent change in expected survival by BCS RT was examined using Accelerated Failure Time (AFT) models. Confounding bias was assessed by comparing effects between adjusted and partially adjusted associations using a fully specified structural model.

Results

The final sample had 2675 beneficiaries with mean age of 75, with 81% 5-year survival from diagnosis. Unadjusted percentage increase in expected survival was 2.75 times greater in the RT group vs. non-RT group, with 5-year survival of 85% vs 60%; fully adjusted percentage increase was 1.70 times greater, with 5-year rates of 83% vs 71%. Quantification of incremental confounding showed age accounted for 71% of the effect reduction, followed by tumor features (12%), comorbidity (10%), dual status(10%), and institutionalization (8%). Adjusting for age and tumor features only resulted in only 4% bias from fully adjusted percent change (70% change vs 66%).

Conclusion

Quantification of confounding aids in determining covariates to adjust for and in interpreting raw associations. Substantial confounding was present (60% of total association), with age accounting for the largest share (71%); adjusting for age plus tumor features corrected for most of the confounding (4% bias). The direct effect of BCS RT on OS accounted for 40% of the total association.
Correction to: Genetic and clinical characterization of BRCA-associated hereditary breast and ovarian cancer in Navarra (Spain)
Authors: de Sabando Ainara Ruiz , Lafuente Edurne Urrutia , García-Amigot Fermín , Sánchez Angel Alonso , Garofalo Lourdes Morales , Moreno Sira , Ardanaz Eva , Ramos-Arroyo Maria A.
Published: December 2019

Following publication of the original article [1], the authors reported an error in Figure 2, where the color code of the text boxes is reversed. Figure 2-amended shows the correct color association between the text boxes and the different areas in the map: Navarra, neighbouring communities and other Spanish communities.
Correction to: Total hip arthroplasty with modular stem for Crowe I and II developmental dysplasia of the hip
Authors: Kong Xiangpeng , Sun Yunming , Yang Minzhi , Zhou Yonggang , Chen Jiying , Chai Wei , Wang Yan
Published: December 2019

In the original publication of this article [1], an sentence needs to be added in the end of the caption of Figure 1 and Figure 3: cited in our previous study [18].
Association of CD58 polymorphism and multiple sclerosis in Malaysia: a pilot study
Authors: Ching Yee Ming , Viswanathan Shanthi , Mohamed Nor Nurhanani , Shuib Shuwahida , Kamarudin Balqis , Mansor Salawati , Yusof Ainur Yusniza , Arip Masita
Published: December 2019

Background

Multiple sclerosis is an immune mediated disease targeting the central nervous system. Association of non-human leukocyte antigen gene,CD58, with multiple sclerosis has been reported in several populations but is unclear among Southeast Asians. This pilot study was conducted to explore the association betweenCD58polymorphism and multiple sclerosis among the Malay population in Malaysia.

Methods

Blood samples were collected from 27 multiple sclerosis patients, and compared with 58 age- and gender matched healthy individuals. All patients were tested negative for anti-aquaporin 4. DNA was extracted from the blood and genotyped for 3 single nucleotide polymorphisms rs12044852, rs2300747 and rs1335532 of geneCD58by real-time PCR.

Results

The majority of multiple sclerosis patients were female (85.2%). The general mean age of onset was 30.5 years. Genotyping results showed that frequencies of the alleles were between 40 and 50% for MS patients and healthy individuals. Association (allelic model) between multiple sclerosis andCD58gene polymorphism alleles rs12044852 (p = 0.410), rs2300747 (p = 0.881) and rs1335532 (p = 0.407) were indistinct.

Conclusions

The impact of theCD58gene polymorphism was not prominent in this pilot study, implying that genetic composition contributing to multiple sclerosis may be different between different populations, thus results in a heterogeneity of disease manifestation and distribution.
Controlling Coordination Number of Rhodium(III) Complex by Ligand-Based Redox for Catalytic C–H Amination
Authors: Fujita Daiki , Kaga Akira , Sugimoto Hideki , Morimoto Yuma , Itoh Shinobu
Published: December 2019

The rhodium (III) complexes supported by a di-deprotonated o-phenylenediamido ligand, ([Cp*RhIII(C6H4N2tBu2Ph22−)] ([Cp*RhIII(L2−)], 1), and one-electron and two-electron oxidized ligands, [Cp*RhIII(C6H4N2tBu2Ph2•−)(CN)] ([Cp*RhIII(L•−)(CN)], 2) and [Cp*RhIII(C6H4N2tBu2Ph20)(CN)]+ ([Cp*RhIII(L0)(CN)]+, 3) (H2L = H2C6H4N2tBu2Ph2 = N,N-di-(3,5-di-tert-butylphenyl)benzene-1,2-diamine)), have been synthesized and characterized by 1H NMR, ESI–mass, EPR, UV-vis spectroscopic methods, and cyclic voltammetry as well as single-crystal structure analysis. In complexes 2 and 3, a cyanide ion coordinates to each rhodium(III) center to stabilize the six-coordinate structures. Catalytic activity of these complexes has been examined in the intramolecular C–H amination of trisylazide (2,4,6-triisopropylphenylsulfonyl azide) to find that complex 2 shows the highest activity. The result suggests that single-electron transfer takes place from the anion radical ligand C6H4N2tBu2Ph2•− of 2 to trisylazide to form a nitrene radical bound rhodium(III) active species for the C–H amination.
Validation of in-house knowledge-based planning model for advance-stage lung cancer patients treated using VMAT radiotherapy
Authors: Tambe Nilesh S , Pires Isabel M , Moore Craig , Cawthorne Christopher , Beavis Andrew W
Published: December 2019

Objectives:

Radiotherapy plan quality may vary considerably depending on planner’s experience and time constraints. The variability in treatment plans can be assessed by calculating the difference between achieved and the optimal dose distribution. The achieved treatment plans may still be suboptimal if there is further scope to reduce organs-at-risk doses without compromising target coverage and deliverability. This study aims to develop a knowledge-based planning (KBP) model to reduce variability of volumetric modulated arc therapy (VMAT) lung plans by predicting minimum achievable lung volume-dose metrics.

Methods:

Dosimetric and geometric data collected from 40 retrospective plans were used to develop KBP models aiming to predict the minimum achievable lung dose metrics via calculating the ratio of the residual lung volume to the total lung volume. Model accuracy was verified by replanning 40 plans. Plan complexity metrics were calculated using locally developed script and their effect on treatment delivery was assessed via measurement.

Results:

The use of KBP resulted in significant reduction in plan variability in all three studied dosimetric parameters V5, V20 and mean lung dose by 4.9% (p = 0.007, 10.8 to 5.9%), 1.3% (p = 0.038, 4.0 to 2.7%) and 0.9 Gy (p = 0.012, 2.5 to 1.6Gy), respectively. It also increased lung sparing without compromising the overall plan quality. The accuracy of the model was proven as clinically acceptable. Plan complexity increased compared to original plans; however, the implication on delivery errors was clinically insignificant as demonstrated by plan verification measurements.

Conclusion:

Our in-house model for VMAT lung plans led to a significant reduction in plan variability with concurrent decrease in lung dose. Our study also demonstrated that treatment delivery verifications are important prior to clinical implementation of KBP models.

Advances in knowledge:

In-house KBP models can predict minimum achievable lung dose-volume constraints for advance-stage lung cancer patients treated with VMAT. The study demonstrates that plan complexity could increase and should be assessed prior to clinical implementation.
Radiopathological correlations of myopericytomas of the hand: emphasis on the MRI perivascular pushing growth pattern
Authors: Crombé Amandine , Bouhamama Amine , Loarer François Le , Kind Michèle
Published: December 2019

Myopericytomas are exceedingly rare soft-tissue tumors with less than 10 cases including radiological depictions. We report three new cases of benign myopericytomas located in the soft-tissues of the hand in adult patients. A pre-treatment MRI was available for all patients and systematically evidenced well-defined, lobulated tumors closely related to the superficial palmar vascular arch and/or digital vessels with a perivascular pushing growth pattern that correlated with pathological findings. Though rare, this small case series show that myopericytomas display recurrent imaging features that could support their radiological diagnosis.
Ultrasound-guided caudal epidural steroid injection in chronic radicular low back pain: short-term electrophysiologic benefits
Authors: Ibrahim Maha Emad , Awadalla Magdy Ahmed , Omar Aziza Sayed , al-Shatouri Mohammad
Published: December 2019

Objective:

To assess the short-term efficacy of ultrasound-guided caudal epidural steroid injections (ESIs) in improving pain, and nerve function as measured by electrophysiological testing in chronic radicular low back pain.

Methods:

Patients diagnosed with chronic radicular low back pain were randomized into one of two groups. The injection group (n = 20) underwent a single ultrasound-guided Caudal ESI of 1 ml of 40 mg ml−1Triamcinolone Acetonide (Kenacort-A), with local anesthetic. The control group (n = 20) underwent a 12-session physiotherapy program. Both groups were evaluated before and 2 weeks after the intervention using visual analog scale for pain and electrophysiological testing comprising peroneal and tibial terminal motor latencies and F-response latencies and chronodispersion.

Results:

Both groups showed significant pain reduction on the visual analog scale after the intervention. The injection group showed a significant reduction in F wave chronodispersion post-treatment (<0.01). In the control group, there were no significant differences in F wave parameters pre- and post-treatment (p > 0.05).

Conclusion:

Caudal ESIs were shown to provide short-term improvement of nerve function as evident by improvement in the electrophysiological parameters sensitive to radiculopathy. It was found to be superior to standard physical therapy in this regard.

Advances in knowledge:

This work shows a novel electrophysiologic evidence of the short-term efficacy ultrasound-guided caudal ESI.
Mandibular radiomorphometric parameters of women with cemento-osseous dysplasia
Authors: Kato Camila NAO , Barra Sâmila G , Pereira Mateus JC , Gomes Lucas TF , Amaral Tânia MP , Abreu Lucas G , Brasileiro Cláudia B , Mesquita Ricardo A
Published: December 2019

Objective:

To compare the radiomorphometric parameters of mandibular trabecular and cortical bone of females with and without cemento-osseous dysplasia (COD).

Methods

A retrospective cross-sectional paired study was conducted. Digital panoramic radiographs were obtained from females diagnosed in a public service of Oral Medicine. The participants were divided into two groups of 50 subjects each: females with a diagnosis of COD (COD group) and females without a diagnosis of COD (non-COD group), randomly chosen from the image database and paired for age. The radiomorphometric parameters analyzed were: mandibular cortical width (MCW), fractal dimension (FD) and mandibular cortical index (MCI). The paired t-test and Wilcoxon test were used to compare MCW and FD values and the McNemar-Bowker test compared the MCI.

Results

The mean age of both groups was 46.84 ± 11.38 years. The median MCW index was 3.12 mm (2.15–4.55) for the COD group and 3.52 mm (1.90–4.70) for the non-COD group (p = 0.034). The mean FD value of the COD group (1.2039 ± 0.0926) was lower than that of the non-COD group (1.2472 ± 0.0894) in the anatomical region of the interest of mandibular cortical bone (p = 0.031), while no difference was detected in alveolar trabecular bone. The C3 degree of MCI was more frequent in the COD group (p = 0.009).

Conclusion:

Females with COD had lower values of radiomorphometric parameters in mandibular cortical bone than females of the same age without COD. These results suggest that, in addition to the dental care recommended in the literature, COD females also require more attention and screening for low bone mineral density.
INFLUENCE OF THE ß SOLAR WIND PARAMETER ON STATISTICAL CHARACTERISTICS OF THE Ap INDEX IN THE SOLAR ACTIVITY CYCLE
Authors: Zotov Oleg , Klain Boris , Kurazhkovskaya Nadezhda
Published: December 2019

In this paper, we use numerical experiment methods to address the problem of determining characteristics of ULF (0.3–3 kHz) electromagnetic waves recorded in the surface layer and providing the maximum amount of information about the Earth–ionosphere waveguide. We have analyzed the effect of the horizontal spatial structure of electron density of the Earth–ionosphere waveguide on propagation of electromagnetic waves. We have identified characteristics that allow us to record them by instrumental methods in conditions of weakly disturbed ionosphere. The density profiles used in numerical experiments have been obtained from data acquired by the Partial Reflection Radar at the Polar Geophysical Institute, located at the radiophysical observatory Tumanny in the Murmansk Region (69.0° N, 35.7° E), and by the IRI2016 model during the March 15, 2013 solar flare and the subsequent magnetic storm on March 17, 2013. The electromagnetic signal propagation model used in this work is the adaptation of gas-hydrodynamic methods to electrodynamic applications. The model is based on the scheme of upwind approximation of spatial derivatives (Godunov’s method with correction of streams). We also use splitting by spatial directions and physical processes. Signal field attenuation due to conductivity and its rotation due to Hall conductivity of the medium are considered in separate splitting steps by analytical formulas.
A Review of the Healthcare-Management (Modeling) Literature Published in Manufacturing & Service Operations Management
Authors: Keskinocak Pinar , Savva Nicos
Published: December 2019

Healthcare systems throughout the world are under pressure to widen access, improve efficiency and quality of care, and reduce inequity. Achieving these conflicting goals requires innovative approaches, utilizing new technologies, data analytics, and process improvements. The operations management community has taken on this challenge: more than 10% of articles published in Manufacturing & Service Operations Management (M&SOM) in the period from 2009 to 2018 have developed analytical models that aim to inform healthcare operational decisions and improve medical decision making. This article presents a review of the research published in M&SOM on healthcare management since its inception 20 years ago and reflects on opportunities for further research.
Social Support Perceived by Family and Caregivers of Children with Cancer
Authors: Silva Santos William Messias , Silva Santos Jaqueline , Marques Hilári Jeniffer Stephanie , Cardoso Maia Maria Ambrosina , Andrade Raquel Dully , Halboth Nadia Veronica
Published: December 2019

Social support to caregivers and family members can contribute to the construction of coping strategies in pediatric cancer diagnosis scenarios. To identify the state of the current literature concerning social support perceived by families and caregivers of children with cancer was the aim of this study. This is an integrative literature review performed in the LILACS and PubMed databases. We selected 10 articles that met the following inclusion criteria: academic articles published from 2014 to 2018, in English, Spanish and/or Portuguese, available in full and as open access, and addressing social support to the family and/or caregivers of children with cancer. The content of the selected articles was organized into the themes “Social support from interpersonal relationships” and “Social support from the health network”, which consider social support as a relevant and significant element in coping with the context of the family living the experience of having a child with cancer. The selected studies showed family members, parents of other children experiencing a similar problem, co-workers, as well as teachers and colleagues of other children as important sources of support. The health network was also an essential source of support, in the assistance, information, instruction, emotional and mediation dimensions of the community resource network. Thus, according to this integrative review, caregivers and family can be supported in different ways, both material and immaterial, and by people who belong to the most diverse social roles.
Þrástef, þagnir og mótsagnir um lýðræðislegt hlutverk íslenskra háskóla
Authors: Bjarnadóttir Valgerður S. , Ólafsdóttir Anna , Geirsdóttir Guðrún
Published: December 2019

Markmið þessarar greinar er að varpa ljósi á orðræðu um lýðræðislegt hlutverk íslenskra háskóla með greiningu á ráðandi stefnumótunarskjölum um háskóla. Þær spurningar sem leitast verður við að svara eru hvort og hvernig orðræða í opinberum stefnuskjölum um háskóla endurspeglar a) lýðræðislegt hlutverk háskóla og b) hvernig háskólum er ætlað að búa nemendur undir ábyrga þátttöku í lýðræðissamfélagi. Valin voru til greiningar lykilskjöl þar sem lagaumgjörð og stefna íslenskra háskóla birtist. Skipta má úrtakinu í þrennt, þar sem skjölin draga fram stefnu háskóla á þremur ólíkum stigum; frá heildarstefnu hins opinbera, til þeirra hugmynda og áhersluatriða sem háskólarnir velja að draga fram í stefnum sínum, og til ætlaðrar framkvæmdar eins og hún er sett fram í ársskýrslum skólanna. Niðurstöður greiningarinnar benda til þess að hugmyndir um lýðræðislegt hlutverk háskóla í opinberum stefnuskjölum séu óljósar og ómótaðar. Stefnur og ársskýrslur háskólanna endurspegla þó ákveðna lýðræðisáherslu, en þrástefið um gæði og samkeppnishæfni skyggir á þá áherslu.
The relationship between state funding and volunteer levels in voluntary sector organisations: a quantitative analysis of regulatory data
Authors: Damm Christopher
Published: December 2019

There is a long-standing debate within voluntary sector studies concerning the relationship between state funding and volunteer levels within voluntary sector organisations (VSOs). Due to a lack of suitable data, this debate has previously suffered from a lack of aggregate, quantitative evidence at the sector level. This article helps to fill this gap by exploring the relationship among larger charities in England and Wales (those with an annual income over £500,000), using a relatively new regulatory dataset on charity funding sources. The findings reveal a complicated relationship, with some small to moderate associations between the key variables. Among VSOs with at least some state funding, state income is correlated with smaller proportions of volunteers, even after controlling for size and industry. However, those with no state funding at all appear less likely to use volunteers, and to use them in lower average numbers, than those with at least some state income.
We would rather be leaders than parliamentarians: women and political office in Ghana
Authors: Bauer Gretchen , Darkwah Akosua K.
Published: December 2019

Ghana, an emerging democracy, lags far behind in women’s representation in Parliament. This article, based on interviews with delegates, aspirants, candidates, Members of Parliament and potential female presidential candidates, suggests that women are dissuaded from standing for Parliament by the exorbitant ‘cost of politics’, humiliating ‘politics of insult’ and keen appreciation of Parliament’s limitations. Still, women may be eager to hold appointive office. Until new democracies are established with electoral systems devoid of costly and insulting electoral politics, and with elected offices in which women may accomplish important goals, women will not exhibit the political ambition to participate in those spaces.
Optical design and fabrication of an all-aluminum unobscured two-mirror freeform imaging telescope
Authors: Xie Yongjun , Mao Xianglong , Li Jinpeng , Wang Fengbiao , Wang Peng , Gao Rong , Li Xing , Ren Shangjie , Xu Zhichen , Dong Rongguang
Published: December 2019

Freeform optics offers more degrees of freedom to optical design that can benefit from a compact package size and a large field of view for imaging systems. Motivated by the advances in modern optical fabrication and metrology, freeform optics has been found in many applications. In this paper, we will describe the challenging optical design, fabrication, metrology, and assembly of an all-aluminum unobscured two-mirror freeform imaging telescope. The telescope has a large field of view of

20

∘

×

15

∘

. The freeform aluminum mirrors are manufactured by diamond turning based on a feedback modification strategy. The freeform mirrors are measured by a computer-generated hologram-based interferometric null test method. All-aluminum configuration has the advantages of being athermal and cost-effective.
Revisiting comparison between entanglement measures for two-qubit pure states
Authors: Singh Ashutosh , Ahamed Ijaz , Home Dipankar , Sinha Urbasi
Published: December 2019

Given a non-maximally entangled state, an operationally significant
question is to quantitatively assess as to what extent the state is
away from the maximally entangled state, which is of importance in
evaluating the efficacy of the state for its various uses as a
resource. It is this question which is examined in this paper for
two-qubit pure entangled states in terms of different entanglement
measures such as negativity (N), logarithmic negativity (LN), and
entanglement of formation (EOF). Although these entanglement measures
are defined differently, to what extent they differ in quantitatively
addressing the earlier mentioned question has remained uninvestigated.
The theoretical estimate in this paper shows that an appropriately
defined parameter characterizing the fractional deviation of any given
entangled state from the maximally entangled state in terms of N is
quite different from that computed in terms of EOF, with their values
differing up to

∼

15
%

for states further away from the
maximally entangled state. Similarly, the values of such fractional
deviation parameters estimated using the entanglement measures LN and
EOF also strikingly differ among themselves, with the maximum value of
this difference being around 23%. This analysis is complemented by
illustration of these differences in terms of empirical results
obtained from a suitably planned experimental study. Thus, such an
appreciable amount of quantitative non-equivalence between the
entanglement measures in addressing the experimentally relevant
question considered in the present paper highlights the requirement of
an appropriate quantifier for such intent. We indicate directions of
study that can be explored towards finding such a quantifier.
TE-wave propagation in graded waveguide structures
Authors: Dalarsson Mariana , Nordebo Sven
Published: December 2019

We investigate TE-wave propagation in a hollow waveguide with a graded dielectric layer, described using a hyperbolic tangent function. General formulae for the electric field components of the TE-waves, applicable to hollow waveguides with arbitrary cross sectional shapes, are presented. We illustrate the exact analytical results for the electric field components in the special case of a rectangular waveguide. Furthermore, we derive exact analytical results for the reflection and transmission coefficients valid for waveguides of arbitrary cross sectional shapes. Finally, we show that the obtained reflection and transmission coefficients are in exact asymptotic agreement with those obtained for a very thin homogeneous dielectric layer using mode-matching and cascading. The proposed method gives analytical results that are directly applicable without the need of mode-matching, and it has the ability to model realistic, smooth transitions.
Convencionalismo jurídico e inteligibilidad del Derecho. El uso como espejo de las fuentes sociales en la teoría jurídica de Andrei Marmor
Authors: Zambrano Pilar
Published: December 2019

El debate acerca de la relación entre el derecho y otros órdenes axiológicos se ha focalizado, en términos generales, en la justificación de la obligatoriedad del derecho. En este trabajo abordamos este debate genérico desde la perspectiva alternativa de la inteligibilidad de las fuentes del derecho y la objetividad de la identificación judicial de las acciones productoras/modificatorias/extintoras del derecho. En esta línea, afirmamos la tesis de que la inteligibilidad de las fuentes sociales supone su conexión necesaria, no a un orden normativo previo —de principios y reglas deónticas—, sino a un orden antropológico y axiológico previo y, más precisamente, a una tipología dada —no convencional— de acciones intencionales.
Aquaponia em Educação Ambiental – Perceções de alunos e de professores
Authors: Martins Pedro
Published: December 2019

A aquaponia é uma atividade que conjuga a aquacultura com a hidroponia e tem sido utilizada em programas de educação ambiental em vários países. Neste estudo pretende-se conhecer as perceções de alunos e de professores relativamente à introdução formal do conceito de aquaponia no currículo de um curso profissional em Portugal. Para tal, realizou-se um inquérito por questionário a uma amostra de alunos e realizaram-se entrevistas semi-estruturadas a uma amostra de professores, envolvidos, direta ou indiretamente, na lecionação do tema. De uma forma geral, o tema foi considerado pertinente e adequado ao currículo, por parte dos alunos. Os professores encontraram alguns problemas na implementação do conceito mas propuseram várias soluções para os ultrapassar.
ADMISSIBILIDADE DA QUEBRA DO SIGILO DO WHATSAPP NA INVESTIGAÇÃO CRIMINAL: À LUZ DO PRINCÍPIO DA PRIVACIDADE
Authors: Motta Debora
Published: December 2019

A presente pesquisa busca analisar a quebra do sigilo, relativo ao uso do aplicativo WhatsApp, na prática das condutas criminosas, verificando a interpretação extensiva das normas jurídicas realizada por meio dos aplicadores da lei, devido à ausência de norma regulamentadora própria que aborde a questão criminal das novas tecnologias comunicacionais. Desse modo, busca-se verificar a possibilidade da aplicação das leis vigentes, criadas sem prever o avanço descontrolado da tecnologia ou seu uso como ferramenta da criminalidade, como explorar a admissibilidade de aplicação análoga a situações concretas semelhantes, mas substancialmente diversas. Além disso, verificar os entendimentos jurisprudenciais sobre a temática da quebra de sigilo, informações e dados do referido aplicativo, bem como apresentar indícios de consequências a violação dos direitos constitucionais e os limites da atuação Estatal na busca de elementos probatórios. Trata-se de pesquisa bibliográfica, realizada sobre o método dedutivo, pautada emfundamentação doutrinária, aplicação da legislação especial que trata da interceptação telefônica e entendimentos jurisprudenciais, notadamente em julgados dos tribunais, especialmente o Tribunal de Justiça catarinense e os Tribunais Superiores, fazendo uma análise dos principais entendimentos e discordâncias existentes.
A EFICÁCIA DO DEPOIMENTO ESPECIAL NA BUSCA PELA PROTEÇÃO À INTEGRIDADE PSICOLÓGICA DE CRIANÇAS E ADOLESCENTES VÍTIMAS DE VIOLÊNCIA SEXUAL
Authors: Nardelli Taianara
Published: December 2019

O presente artigo busca examinar se o depoimento especial é eficaz na busca pela proteção à integridade psicológica de crianças e adolescentes vítimas de violência sexual. Sabe- se que o crime de violência sexual traz inúmeras consequências, especialmente para crianças e adolescentes que ainda se encontram em estado de desenvolvimento. Neste sentido, originou-se um projeto, inicialmente chamado de ‘depoimento sem dano’, que resultou na promulgação da Lei n. 13.431/17, a qual objetiva reduzir a vitimização causada pela inquirição em juízo e facilitar o entendimento pela vítima acerca da necessidade de explicitar de forma clara e verdadeira o ilícito ocorrido, com a utilização de profissionais especializados para tanto. O projeto é fruto de inúmeros estudos que trazem essa metodologia de inquirição menos danosa e mais garantista de direitos, visando sua dignidade e integridade, e concomitantemente, o auxílio na busca pela verdade. O método de abordagem utilizado na elaboração desse artigo foi o indutivo. O levantamento de dados foi através da técnica da pesquisa bibliográfica. O ramo de estudo é na área do Direito Penal e Processual Penal.
DIREITO À PRIVACIDADE NA LEI GERAL DE PROTEÇÃO DE DADOS PESSOAIS
Authors: Carvalho Gisele Primo , Pedrini Taina Fernanda
Published: December 2019

O direito à privacidade, previsto no art. 5°, inciso X, da Constituição da República Federativa do Brasil de 1988 (CRFB/88) é constitucionalmente assegurado a todos, em decorrência da universalidade dos direitos fundamentais, a qual assegura, sob a perspectiva informacional, ao indivíduo o controle de suas próprias informações pessoais. Nesse sentido, pesquisa-se o núcleo essencial desse direito para, posteriormente, compreender as implicações jurídicas advindas a partir da promulgação de legislações infraconstitucionais, em especial, a Lei n. 13.709/2018, conhecida como Lei Geral de Proteção de Dados (LGPD) e o Marco Civil da Internet, Lei n. 12.737/14. Por conseguinte, explanam-se as disposições legais da LGPD, as quais têm por finalidade a proteção do usuário nas relações que envolvem a disponibilização de dados pessoais, inclusive, os dados considerados sensíveis. Por fim, averiguam-se pontos vulneráveis da LGPD, notadamente, no que diz respeito aos vetos presidenciais. Nesse viés, conclui-se que, com a promulgação da referida lei, o direito à privacidade, principalmente, no que se refere à proteção de dados pessoais, recebeu amparo jurídico específico, entretanto, ainda assim, vislumbra-se necessidade de complementá-la, na medida em que, são identificados alguns impasses jurídicos na implementação efetiva das disposições legais, em especial, a previsibilidade da Autoridade Nacional de Proteção de Dados Pessoais, bem como a tipificação de penalidades mais severas. O método utilizado foi o indutivo.
Detecção de mudanças na cobertura vegetal natural do Cerrado por meio de dados de radar (Sentinel-1A) e plataforma Google Earth Engine
Authors: Rodrigues Thaise da Silva , Sano Edson Eyji , Prieto Juan Doblas , De Almeida Tati , Chaves Joselisa Maria
Published: December 2019

A detecção de mudanças na cobertura vegetal natural do Cerrado vem sendoconduzida por meio de imagens orbitais ópticas. Com a disponibilização semcustos das imagens de radar do satélite Sentinel-1A, o monitoramentocontínuo e em tempo quase real de mudanças na sua cobertura vegetalnatural tornou-se uma realidade. O objetivo desse estudo é analisar opotencial das imagens do satélite Sentinel-1A para detecção de mudanças nacobertura vegetal natural do Cerrado para fins de fiscalização e controle dedesmatamentos ilegais. A área-teste selecionada foi o Oeste da Bahia. Foramconsideradas duas cenas do Sentinel-1A obtidas em 03 de outubro de 2016(T0) e 27 de outubro de 2017 (T1) na banda C, resolução espacial de 20metros e polarizações VV e VH. Um conjunto de 159 polígonos dedesmatamento identificados em oito cenas do satélite Landsat-8 OperationalLand Imager (OLI) de 2016 e 2017 foram utilizados como áreas detreinamento para definir os coeficientes de retroespalhamento (ï³ï‚°) típicos deáreas de mudanças na cobertura vegetal natural da área-teste. O potencial dedetecção de mudanças foi analisado por meio de gráficos boxplot envolvendovalores de ï³ï‚° derivados da razão T1/T0 (sem filtragem e processados pelosfiltros Refined Lee e Quegan & Yu). Foram considerados três limiares demudança para cada polarização. Todo o processamento de imagens de radarfoi realizado na plataforma Google Earth Engine. O melhor resultado foiobtido para a combinação VH, Refined Lee e limiar 0,60, a qual apresentou95% de acurácia e 39% de omissão.
LA MEMORIA COMO BOOMERANG ¿QUÉ QUEDA DEL CORDOBAZO?
Authors: SERVETTO ALICIA , ORTIZ LAURA
Published: December 2019

La conmemoración de los 50 años del Cordobazo es una oportunidad para revisar su historia, las condiciones que lo hicieron posible y las consecuencias que produjo. También es una ocasión para examinar la(s) memoria(s), debatir sobre sus significados en el presente y ensayar respuestas a la no siempre cómoda pregunta acerca de ¿Qué queda del Cordobazo? Como volverse sobre un espejo roto, la pregunta despliega antiguas cuestiones revisadas con lecturas actuales, y nuevos interrogantes que abren viejas discusiones: ¿Fue el Cordobazo una respuesta del movimiento obrero a la política  conómica de Krieger Vasena que atentaba contra los salarios y condiciones laborales? ¿Fue el Cordobazo la culminación de una etapa de luchas y resistencia iniciada en 1955? o ¿Fue el inicio de un nuevo ciclo marcado por la politización y la radicalización ideológica?, ¿Se trató de una gesta sólo de hombres?, ¿Resultaba una novedad el activismo y la participación de los estudiantes y los jóvenes? Desandar cada una de estas preguntas nos obliga a pensar críticamente el pasado, sin caer en la tentación solo de rememorar o, en su defecto, de hacer de aquel acontecimiento un mito de la gesta popular. Por el contrario, se trata de actualizar y analizar ese pasado que vuelve y nos interpela con preguntas, con paradojas y con contradicciones.
Analytical foundation of the planimeter
Authors: Vela Urrego Claudia , Sarmiento Sarmiento Edilberto , Bustos Velazco Edier Hernan
Published: December 2019

One of the main objectives of topographic surveys has allowed to draw maps or plans of an area of a limited region or terrain, showing physical characteristics of the terrain, such as rivers, lakes, reservoirs, roads, forests, rock formations, ponds, dams, dikes, drainage pits or water supply channels. The accuracy of the measurement will depend on the scale of the map, the method and the instruments utilized. This document provides the mathematical fundamentals of the planimeter, that allows to measure the area of uneven or spherical flat surfaces; this instrument is important in topographic engineering. The knowledge, and the analityc foundation, of this instrument, makes the article not only of a pedagogical nature, but also it provides a historical development depicting its evolution and leading to its digital current version.
Desarrollo de competencias lecto-escriturales mediante un prototipo de sistema de información
Authors: Simanca Herrera Fredys Alberto , Blanco Garrido Fabian , Cifuentes Velásquez Claudia Marcela
Published: December 2019

Lee+ es un prototipo funcional que pretende motivar y estimular la lectura en los estudiantes brindando al docente herramientas para crear actividades sincrónicas y asincrónicas, dado que el proceso lector es inherente al individuo y de él depende el permitir el mejoramiento de las competencias lecto-escriturales. Por tanto, este proyecto se abordó con el uso de la web 2.0 mediante su desarrollo en la red social Facebook donde se planteó apoyar el proceso de enseñanza-aprendizaje brindando un espacio de acercamiento entre docente y estudiante. Para ello se utilizó un enfoque cuantitativo como corriente de pensamiento para la generación del conocimiento. Adicionalmente, se permitió la inclusión en las actividades de componentes multimedia con el fin de facilitar el fortalecimiento de las competencias en lectura y escritura, sin embargo, cabe mencionar que para lograr avances significativos es necesario el compromiso de los estudiantes con el quehacer del aprendizaje
Aplicación de los videojuegos en el ámbito educativo
Authors: Acosta Cipagauta Christian , Bernal Gómez Mireya
Published: December 2019

Hoy en día los videojuegos son más que una forma de entretenimiento, ocio o simplemente ocupar el tiempo, su uso y aplicación en diferentes contextos ha sido una revolución, ya que se han vuelto una herramienta en diferentes sectores: industria, redes sociales, salud y educación. La educación en Colombia ha tenido cambios significativos, una búsqueda constante de instrumentos y metodologías que permitan al estudiante desarrollar sus conocimientos y creatividad, es por esto que las instituciones educativas han optado por nuevas formas de transmitir la información y los conocimientos a los estudiantes: así, los videojuegos entran a ser parte fundamental del proceso educativo, ya que por medio de estos, los conceptos y argumentos son más fáciles de aprender, de acuerdo al contexto.
The Influence of Self-Employment on Early-Stage Entrepreneurship in Romania. A Global Entrepreneurship Monitor-Based Analysis
Authors: Györfy Lehel , Madaras Szilárd
Published: December 2019

The self-employment occupational status has a determinant role in the entrepreneurship development, including generally almost all sectors of the national economy. In this paper, we will focus on this topic. The statistical analysis of this occupational status and its implications on entrepreneurship in Romania in 2015 were considered based on the INSE statistical database, followed by an analysis based on a GEM 2015 (Global Entrepreneurship Monitor) database regarding the main factors influencing early-stage entrepreneurship. To describe the start-up intention and start-up effort, setting out from the literature, we included a set of indicators into the logistic regression analysis as follows: age, income, gender, education, working status, existence of entrepreneur acquaintances, confidence in one’s own knowledge, skill, and experience, completing the set with the presence of self-employment, as new research suggests it.
Signal and error assessment of GOCE-based high resolution gravity field models
Authors: Gruber T. , Willberg M.
Published: December 2019

The signal content and error level of recent GOCE-based high resolution gravity field models is assessed by means of signal degree variances and comparisons to independent GNSS-levelling geoid heights. The signal of the spherical harmonic series of these models is compared to the pre-GOCE EGM2008 model in order to identify the impact of GOCE data, of improved surface and altimetric gravity data and of modelling approaches. Results of the signal analysis show that in a global average roughly 80% of the differences are due to the inclusion of GOCE satellite information, while the remaining 20% are contributed by improved surface data. Comparisons of the global models to GNSS-levelling derived geoid heights demonstrate that a 1 cm geoid from the global model is feasible, if there is a high quality terrestrial gravity data set available. For areas with less good coverage an accuracy of several centimetres to a decimetre is feasible taking into account that GOCE provides now the geoid with a centimetre accuracy at spatial scales of 80 to 100 km. Comparisons with GNSS-levelling geoid heights also are a good tool to investigate possible systematic errors in the global models, in the spirit levelling and in the GNSS height observations. By means of geoid height differences and geoid slope differences one can draw conclusions for each regional data set separately. These conclusions need to be considered for a refined analysis e.g. to eliminate suspicious GNSS-levelling data, to improve the global modelling by using full variance-covariance matrices and by consistently weighting the various data sources used for high resolution gravity field models. The paper describes the applied procedures, shows results for these geoid height and geoid slope differences for some regional data sets and draws conclusions about possible error sources and future work to be done in this context.
Association between neck circumference and non-alcoholic fatty liver disease in Mexican children and adolescents with obesity
Authors: Peña-Vélez Rubén , Garibay-Nieto Nayely , Cal-y-Mayor-Villalobos Manuel , Laresgoiti-Servitje Estibalitz , Pedraza-Escudero Karen , García-Blanco María del Carmen , Heredia-Nieto Omar Alfonso , Villanueva-Ortega Eréndira
Published: December 2019

Background

Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic hepatic disorder in the pediatric population and has grown along with the obesity pandemic in which we live today. Adipose tissue storage in the upper body segment has been positively correlated with visceral adiposity and metabolic disease, which suggests that neck circumference could represent an easily accessible and replicable anthropometric measurement to identify patients with a higher risk of developing NAFLD. The main purpose of this study is to determine if there is an association between neck circumference and NAFLD. The secondary objectives are to establish cutoff values based on gender and puberty staging.

Methods

We included a sample pediatric population of 112 patients diagnosed with obesity aged between 6 and 18 years. We performed anthropometric and metabolic measurements on every patient, and NAFLD diagnosis was determined with hepatic ultrasound.

Results

The neck circumference was larger in NAFLD pediatric patients compared to those without NAFLD (p = 0.001). In a multivariate analysis, the neck circumference was associated with NAFLD as an independent risk factor (odds ratio [OR] = 1.172; 95% CI = 1.008–1.362; p = 0.038). Tanner 2–3 = 35 cm and Tanner 4–5 = 38 cm were established as risk cutoff values to develop NAFLD in the male adolescent population.

Conclusions

There is an association between the neck circumference and NAFLD in pediatric patients with obesity, particularly in the male population.
The Self and Others: Revisiting Information Needs and Libraries as Public, Social Institutions in a Post-truth World
Authors: Oliphant Tami
Published: December 2019

The post-truth era and the increasing ease with which fake news is disseminated and consumed is a wicked problem that invites re-examination of the media environment, algorithmic authority, library and information science (LIS) professional practice, and what people bring to information interactions in terms of cognitive biases and worldviews. Fake news has social consequences such as undermining civic discourse and democracy, and inciting hatred. Consequently, the role of libraries as public, social institutions embedded in democratic societies and the relational aspects of information needs are important to consider. An alternative framework, the decent society, a society in which its attendant social institutions do not humiliate, is explored. An example from the Toronto Public Library (TPL) is used to illustrate the ways in which a social institution can uphold the principle of non-humiliation in an increasingly politicized world.
Not Just Disgust: Fear and Anger Also Relate to Intergroup Dehumanization
Authors: Giner-Sorolla Roger , Russell Pascale Sophie
Published: December 2019

One of the most extreme expressions of prejudice is likening groups to non-human beings. Previous research relates disgust to dehumanization of social groups. However, prior studies have not examined other negative emotions in relation to dehumanization. We examined whether three emotions – anger, disgust, and fear – are associated with dehumanization of social groups. In Experiments 1 and 2 we tested these relationships measuring reactions to real groups. We found that all three emotions were uniquely related to animalistic and humanity-denial dehumanization, but only fear was related to mechanistic dehumanization. Using an orthogonal emotion grid measure in Experiment 3, we showed anger to play a primary role in dehumanization among a variety of target groups. Finally, in Experiment 4 we manipulated whether a novel group was abnormal or harmful, and found that both groups elicited more dehumanization than the control group; however, the harmful group elicited dehumanization mediated by anger and the abnormal group elicited dehumanization mediated by disgust. From this evidence, we argue that other emotions besides disgust play an important part in the dehumanization of outgroups.
Psoriasis: Advocating for psychosocial support
Authors: Riahi Aryan
Published: December 2019

.
PRRT in high-grade gastroenteropancreatic neuroendocrine neoplasms (WHO G3)
Authors: Sorbye Halfdan , Kong Grace , Grozinsky-Glasberg Simona
Published: December 2019

Peptide receptor radionuclide therapy (PRRT) is an established treatment for grade 1 and 2 gastroenteropancreatic neuroendocrine tumors with an increased uptake on somatostatin receptor imaging (SRI). Patients with metastatic high-grade (WHO G3) gastroenteropancreatic neuroendocrine neoplasms (NET G3 and NEC) represent a heterogeneous subgroup with poor prognosis and standard platinum-etoposide chemotherapy have limited therapeutic benefit. However, there is promising emerging evidence supporting the effectiveness of PRRT in SRI-positive G3 disease. A review search for studies reporting on PRRT in gastroenteropancreatic neuroendocrine neoplasms G3 was performed: four studies with more than ten cases were found. PRRT was mainly given as second- or third-line treatment in patients with progressive disease. Most patients had a pancreatic primary, 50% had well-differentiated tumors, and most had a Ki-67 <55%. Three studies showed similar results with promising response rates (31–41%) and disease control rates (69–78%). Progression-free survival (11–16 months) and survival (22–46 months) were best concerning patients with a Ki-67 <55%. Progression-free survival was 19 months in NET G3, 11 months for lowNEC (Ki-67 ≤55%) and 4 months for highNEC (Ki-67 >55%). PRRT should be considered for patients with increased uptake on SRI, both in gastroenteropancreatic NET G3 cases and as well as in NEC cases with a Ki-67 21–55%. PRRT for NEC with a Ki-67 >55% is less defined, but could be considered in highly selected cases after response to initial chemotherapy where all residual disease have high uptake on SRI. Dual tracer using 18F-FDG PET/CT and SRI provides important information for patient selection for PRRT in this heterogeneous complex high-grade disease.