bluuebunny/crossref_metadata_2025 huggingface dataset:
Biosystematics a modern tool for identification of South Indian species of Ipomoea linn.
Authors: T. Praveen Dhar
Published: January 2018

Systematics must be perceived as a science that can hold its own image in the current information era, rather than as an old fashioned stamp collecting exercise and this perception must be presented to both the general and public.To build up a natural system of classification of plants, it is necessary to compare one form with another, such parts like stem, leaf, root, flower, fruits and seeds. These superficial examinations are helpful to a certain extent in identifying and classifying the plants. The phenotype of each and every taxon is unique and this uniqueness itself is a clear identifying feature for a taxon. To a certain extent cytological, palynological, anatomical features seen to go in hand with the external morphological features.
In-silico identification of cis- acting regulatory elements in 5’ regulatory region of Betaine aldehyde dehydrogenase isoenzymes of selected monocot and dicot
Authors: Sharma Hemani , Govil Sumit , Shrivastava Divya
Published: January 2018

It’s challenging to understand the multifarious gene regulatory networks. Diverse biological processes, are mostly conferred by nature of cis-acting regulatory elements (CARE) located within the regulatory region which include abiotic stress responses, hormone responses and developmental processes. Thus, the identification of CARE and their organization is a crucial step for better understanding of spatiotemporal expression of the gene. The putative cis-acting element that are located within the 5' regulatory region of BADH isozymes of Hordeum vulgare , Oryza sativa, Sorghum bicolor, Leymus chinensis, Zoysia tenuifolia, Arabidopsis thaliana, Amaranthus hypochondriacus, Chrysanthemum lavandulifolium, Populus euphratica and Atriplex prostrate were identified using bioinformatics tools. Several probable cis-acting regulatory elements that are coupled with cellular development, hormonal and stress response were identified as: Me-JA, GARE, GT-1, MYB, W-box, I-box, Pyrimidine-box, ANAERO, ARF, CARE, ASF1, SORLIP, SURE, TAAAGSTKST1, GCC Box, CICADIAN, Sp1 and CGCG Box. These results shed light on probable cis-acting regulatory elements these BADH isoenzyme that confer their expression and regulation during cellular, hormonal and stress response.
RELATION OF HEART WEIGHT WITH AGE AND WEIGHT OF CADAVER
Authors: Agarwal Jolly , Kumar Virendra
Published: January 2018

Introduction: Height, weight, and age of person has significant impact on the normal size of

heart. These parameters need to be considered when cut-off values indicating the need for

treatment or even surgery are established. The aim of present work is to study the relation of

weight of the heart with age and weight of cadaver.

Material and Methods: The study was performed in the Department of Anatomy, Shri Ram

Murti Smarak Institute of Medical Sciences, Bareilly on 30 hearts from embalmed cadavers.

The hearts were procured from the cadavers available in our department. The heart was

thoroughly cleaned and measurements were taken.

Results: The mean heart weight was 223.37 ± 57.78 g. Significant relationship between age of

the cadaver and weight of the heart (p=0.0004), weight of cadaver and weight of heart

(p=0.0001) was observed.

Conclusion: The above study provides valuable data of the heart in our geographical location,

which may be useful for cardiac surgeons and physicians.
PROSPECTIVE RANDOMIZED STUDY ON TWO DOSE FRACTIONATION REGIMENS OF HIGH DOSE RATE BRACHYTHERAPY FOR CARCINOMA CERVIX: COMPARISON OF CLINICAL RESPONSE AND COMPLICATIONS IN ORGANS AT RISK
Authors: Goswami Saurabh , Kumar Piyush , Chauhan Arvind Kumar , Nigam Jitendra , Singh D. P.
Published: January 2018

Introduction: Cancer Cervix is treated with a combination of external beam radiotherapy and

intracavitary brachytherapy. With the recent American Brachytherapy Society consensus

guidelines for locally advanced carcinoma of the cervix, atleast Equivalent Dose 2 > 80 Gy for

patients with complete response or partial response with residual disease less than 4cm is

recommended. For non responders or those with tumors larger than 4cm at the time of

brachytherapy, tumor dose escalation to an Equivalent Dose 2 of 85-90 Gy is recommended to

point A. Present study was designed to see the feasibility of these guidelines in terms of local

tumor control and toxicities to rectum and bladder in our group of patients.

Material and Methods: Fifty patients of biopsy proven cancer cervix were enrolled. After

pre-treatment evaluation all patients were delivered external beam radiotherapy 50 Gy in 25

fractions at 200 cGy/day with concurrent cisplatin on weekly basis. Patients were then

randomized into three applications (Group A), four applications (Group B) of HDR

Brachytherapy of 6 Gy each so that total treatment time does not exceed 8 weeks. BED and

LQED were calculated and assessment of response and complications were assessed.

Statistical analysis was done using Chi square test.

Results: Mean age of the patients was 50 years. No significant hematological toxicities and

radiation reactions were seen during external beam radiotherapy. The mean BED of group A

for tumor, rectum & bladder was 137.3 Gy, 112.53 Gy & 103.23 Gy respectively and of group

B was 155.3 Gy, 120.98 Gy and 111.95 Gy respectively. The mean EQD2 in group A at tumor,

rectum & bladder was 74 Gy, 54.08 Gy and 61.94 Gy respectively and in group B was 82 Gy,

59.18 Gy and 66.60 Gy respectively. There was no statistically significant difference in local

response and early & late bladder reactions in both the groups.

Conclusion: In a follow-up of six months we did not find any significant difference in

toxicities of rectum and bladder. Long-term follow-up is needed to see for late rectal and

bladder toxicities.
ORAL MUCOSITIS IN PATIENTS OF HEAD AND NECK CANCERS TREATED WITH CHEMORADIOTHERAPY: ASSOCIATED FACTORS AND TREATMENT OUTCOME
Authors: Sharma Manish Kumar , Singh D.P. , Kumar Piyush
Published: January 2018

Introduction: Oral Mucositis develops in nearly all patients receiving radiation therapy for

head and neck cancers. Number of risk factors has been reported to influence the frequency and

severity of Mucositis. The goal of the present study is to evaluate some of the patient and

treatment related factors which make impact on oral mucositis and also to evaluate the impact

of oral Mucositis on treatment outcome.

Material and Methods: Fifty patients were included in this study from July 2014 to June

2016. All the patients were treated with concurrent radiotherapy (70 Gy in 35 fractions in 7

weeks) and chemotherapy (Cisplatin 35 mg/m2 weekly). Clinical Response Assessment was

done as per RTOG Grading and Radiation toxicity was assessed by RTOG Acute & Late

Morbidity Scoring criteria. Statistical analysis was done using Chi Square test and Fischer

Test.

Results: In a patient population of fifty, the intensity of oral Mucositis was correlated with

various patient and treatment related factors. Patient related factors- body mass index ≤18.5

and patients taking tobacco had a higher incidence of Grade III/IV Mucositis (p<0.00 &

p=0.04 respectively). Other factors like age, gender, stage, site of disease and co morbidities

did not show statistical difference in Grade III/IV oral Mucositis. None of the treatment related

factors- total dose of Cisplatin, number of chemotherapy cycles and radiation dose showed

statistical difference in the occurrence of oral Mucositis.

Conclusion: Severe oral Mucositis leads to additional supportive care & even hospitalization.

Targeted interventions need to be developed to reduce the incidence of oral Mucositis.
Attitudes Towards Problem‐Based Learning of Faculty Members at 12 U.S. Medical and Dental Schools: A Comparative Study
Authors: Abdelkarim Ahmad , Schween Dorothy , Ford Timothy
Published: January 2018

Problem‐based learning (PBL) is a teaching method used in medical and dental education to promote students’ problem‐solving skills. It may also be a viable tool for interprofessional education in which medical and dental students learn together, collaborate, and learn about, from, and with each other. The aim of this study was to compare medical and dental faculty members’ attitudes about and perceptions of PBL at 12 U.S. medical and dental schools known to use PBL. In 2015, 111 medical and 132 dental faculty members (combined n=243) from six medical and six dental schools completed a survey containing ten statements and an open comment section. The response rate was 42% of those who received the survey. In the results, the medical faculty participants showed significantly higher enthusiasm for and agreement with PBL benefits than did the dental faculty participants (p˂0.05). The two groups agreed that PBL should be used to supplement conventional teaching (p>0.05). There were no opposite attitudes or contrasts found between the two groups with regards to PBL. The strongest themes expressed by both groups were that PBL should not be used as the sole method of instruction and that students needed a solid foundation in the subject prior to engaging in PBL.
The role and diagnostic significance of cellular barriers after concussive head trauma
Authors: Dadas Aaron , Janigro Damir
Published: January 2018

The onset of concussive head trauma often triggers an intricate sequence of physical consequences and pathophysiological responses. These sequelae can be acute (i.e., hematoma) or chronic (i.e., autoimmune response, neurodegeneration, etc.), and may follow traumas of any severity. A critical factor for prognostication of postconcussion outcome is the pathophysiological response of cellular barriers, which can be measured by several biomarkers of the acute and chronic postinjury phases. We present herein a review on the postconcussion mechanisms of the blood–brain barrier, as well as the diagnostic/prognostic approaches that utilize differential biomarker expression across this boundary. We discuss the role of the blood–saliva cellular barrier as a regulatory filter for brain-derived biomarkers in blood, and its implications for saliva-based diagnostic assays.
La investigación bibliotecológica en América Latina: análisis de su desarrollo
Authors: HERNÁNDEZ SALAZAR PATRICIA
Published: January 2018

EL OBJETIVO DEL TRABAJO ES PRESENTAR UN PANORAMA DE LA INVESTIGACIÓN BIBLIOTECOLÓGICA Y DE LA CIENCIA DE LA INFORMACIÓN EN ALGUNOS PAÍSES DE LA REGIÓN, EN DOS MOMENTOS DIFERENTES: ANTECEDENTES (DÉCADA DE LOS OCHENTA) Y SITUACIÓN ACTUAL (DÉCADA DEL 2000). PARA CADA MOMENTO SE IDENTIFICAN LOS OBJETIVOS, LOS TEMAS O LÍNEAS DE INVESTIGACIÓN, LA PROBLEMÁTICA Y LAS SOLUCIONES Y CON ESTOS ELEMENTOS SE ESTABLECEN LOS OBJETOS DE ESTUDIO. SE HACE UNA COMPARACIÓN ENTRE LOS ANTECEDENTES Y LA SITUACIÓN ACTUAL. ESTOS ANÁLISIS NOS PERMITIERON DETERMINAR UN POSIBLE PARADIGMA DISCIPLINARIO. LOS PAÍSES ESTUDIADOS SON ARGENTINA, BRASIL, COLOMBIA Y MÉXICO.
Bond dimension witnesses and the structure of homogeneous matrix product states
Authors: Navascues Miguel , Vertesi Tamas
Published: January 2018

For the past twenty years, Matrix Product States (MPS) have been widely used in solid state physics to approximate the ground state of one-dimensional spin chains. In this paper, we study homogeneous MPS (hMPS), or MPS constructed via site-independent tensors and a boundary condition. Exploiting a connection with the theory of matrix algebras, we derive two structural properties shared by all hMPS, namely: a) there exist local operators which annihilate all hMPS of a given bond dimension; and b) there exist local operators which, when applied over any hMPS of a given bond dimension, decouple (cut) the particles where they act from the spin chain while at the same time join (glue) the two loose ends back again into a hMPS. Armed with these tools, we show how to systematically derive `bond dimension witnesses', or 2-local operators whose expectation value allows us to lower bound the bond dimension of the underlying hMPS. We extend some of these results to the ansatz of Projected Entangled Pairs States (PEPS). As a bonus, we use our insight on the structure of hMPS to: a) derive some theoretical limitations on the use of hMPS and hPEPS for ground state energy computations; b) show how to decrease the complexity and boost the speed of convergence of the semidefinite programming hierarchies described in [Phys. Rev. Lett. 115, 020501 (2015)] for the characterization of finite-dimensional quantum correlations.
Declaración de Sant Joan d’Alacant en defensa del Acceso Abierto a las publicaciones científicas, del grupo de editores de revistas españolas sobre ciencias de la salud (GERECS)
Authors: Editorial Equipo
Published: January 2018

Noviembre de 2017«Este documento se publica simultáneamente en las revistas que han suscrito la Declaración de Sant Joan d’Alacant del Grupo de Editores de Revistas Españolas sobre Ciencias de la Salud (GERECS) el día 25 de noviembre de 2017».El concepto de Acceso Abierto (Open Access, OA) no sólo tiene que ver con la accesibilidad al documento científico, sino también con los permisos de reutilización más o menos restrictivos en función de los derechos reservados para su distribución. A partir de esta idea, surgieron numerosas iniciativas, con o sin ánimo de lucro, con el fin de facilitar el acceso universal a través de internet a las publicaciones científicas.
Reseña de libro: Revistas científicas: Situación actual y retos de futuro
Authors: Martín Rodero Helena
Published: January 2018

Ficha editorialTítulo: Revistas científicas: Situación actual y retos de futuroEditor: Ernest AbadalEditorial: Edicions de la Universitat de BarcelonaNúmero de páginas: 276ISBN: 978-84-9168-004-8Copyright © Edicions de la Universitat de BarcelonaEste documento está sujeto a la licencia de Reconocimiento-NoComercial-SinObraDerivada de Creative Commons
Synthesis and chemical behaviour of 17α-butyl-3β,17β-dihydroxy-16-oximino-5-androstene
Authors: Stojanovic Srdjan , Molnár-Gábor Dora , Medic-Mijacevic Ljubica , Sakac Marija , Penov-Gasi Katarina
Published: January 2018

Starting from 3 -hydroxy-16-oximino-5-androsten-17-one (1), the recently
synthesized 16-oximino-17 -hydroxy-17 -butyl derivative 2 gave by the
Beckmann fragmentation reactionwith titanium(III) chloride or
p-toluenesulphonyl chloride the corresponding D-seco derivative 3. However,
using acetic anhydride, in addition to the 3 -acetoxy D-seco derivative 4,
the 17-aza D-homo derivative 5 was obtained. The structure of compound 5 was
proposed on the basis of NMR-spectroscopy.
Preparation of some D-glucofuranosides from unprotected D-glucose
Authors: Joniak D. , Poláková M.
Published: January 2018

O-Glycosidation of 3-(4-methoxyphenyl) propyl alcohol, benzyl alcohol and
vanillin with totally unprotected D-glucose, performed in a heterogeneous
media and promoted by anhydrous ferric chloride, afforded competent
D-glucofuranosides as the major and D-glucopyranosides as the minor products
of the reaction.
Synthesis and characterization of thermoplastic copolyester elastomers modified with fumaric moieties
Authors: Aleksandrovic Vesna , Djonlagic Jasna
Published: January 2018

A series of poly(ether-ester)s derived from dimethyl terephthalate (DMT),
dimethyl fumarate (DMF), 1,4-butandiol (BD) and poly(tetramethylene oxide)
(PTMO,Mn = 1000 g/mol) was synthesized in a two stage process involving
transesterification and polycondensation in the melt. The mole ratio of the
starting components was selected to result in copolymers with a constant
hard:soft segment wieght ratio (56:44). The amount of DMF was 10 mol %,
referred to the total amount of the esters used. The synthesis was optimized
in terms of both the concentration of catalyst, tetra-n-butyl-titanate,
Ti(OBu)4 and thermal stabilizerN,N?-diphenyl-p-phenylenediamine, DPPD, as
well as the temperature. The composition and structure of the synthesized
poly(ether-ester)s were characterized by 1H-NMR. The number average
molecular weights of the polymers calculated from the 1H-NMR spectra were
compared with the corresponding values of the inherent viscosity (inh)
inm-cresol and the complex dynamic viscosity (
Narumi-Katayama index of phenylenes
Authors: Tomovic Zeljko , Gutman Ivan
Published: January 2018

The Narumi-Katayama topological indes S of a hydrocarbon is the product of
vertex degrees of the respective molecular graph. If PH is a phenylene and
HS is its hexagonal squeeze, then the respective Narumi-Katayama indices are
related as S(PH) = 9h-1 S(HS), where h is the number of hexagons of PH and
HS, or as S(PH) = S(HS) , where = 0.078 and = 1.613.
New method for solving a class of fractional partial differential equations with applications
Authors: Jafari Hossein , Tajadodi Haleh
Published: January 2018

In this work we suggest a numerical approach based on the B-spline polynomial to obtain the solution of linear fractional partial differential equations. We find the operational matrix for fractional integration and then we convert the main problem into a system of linear algebraic equations by using this matrix. Examples are provided to show the simplicity of our method.
Thermal extras of vegetation walls in Belgrade climatic conditions
Authors: Sudimac Budimir , Andjelkovic Aleksandar , Dubljevic Sanja
Published: January 2018

The goal of this research is to analyse the possibility of using vegetation walls in order to improve the thermal characteristics of office buildings in Belgrade?s climatic conditions. The study analyses the possibility of integrating vegetation modules into the fa?ades of office buildings. The paper shows the potential of vegetation technologies in the realisation of fa?ade coverings of architectural buildings with a goal to reduce heat gained during summer time. The use of vegetation walls in architecture has opened up new planning possibilities and created planning conditions for reducing the energy necessary for cooling office buildings. Considering that interaction between the outer environment and inner solving the dependency between comfort, outer look and building?s energy balance. This paper is presenting the possibility of using sustainable technologies for solving the problem of overheating in Belgrade?s climatic conditions. The research considers the possibilities of using vertically greening systems in planning fa?ade coverings, with an analysis of their thermal characteristics for climatic conditions in Belgrade.
Geographic and technical floating photovoltaic potential
Authors: Tina Giuseppe , Cazzaniga Raniero , Rosa-Clot Marco , Rosa-Clot Paolo
Published: January 2018

The photovoltaic geographic potential (PVGP) is defined as the fraction of the solar irradiation received on the land available for a photovoltaic facility. The area of this usable land is calculated by a suitability factor which is determined by a variety of different geographical constraints. We extend this kind of analysis to floating photovoltaic (FPV) structures and consider the use of water surfaces with the same definitions and notations used to define the PVGP for systems installed on the ground. Results are very promising because of the large water surfaces available and because of the possibility to build floating structures which are more compact than land based photovoltaic plants. In fact, using just 1% of natural basins areas to install FPV plants, about 25% of the world electrical energy demand (in 2014) can be supplied. The PVGP is evaluated for two PVF raft geometries: one is a typical shed structure, the other is an innovative solution named gable.
Enhancing energy performance certificates with energy related data to support decision making for building retrofitting
Authors: Madrazo Leandro , Sicilia Alvaro , Massetti Marco , Plazas Fabian , Ortet Eric
Published: January 2018

The increasing availability of large-scale repositories of energy performance certificates offers the opportunity to interlink them with other data sources (cadastre, geographical data, weather data, building regulations, catalogues of refurbish?ment measures) and to derive innovative services that use the integrated data in conjunction with various tools (energy performance simulation, environmental impact). In the ENERSI project, two applications have been developed to make it easier for building owners and planners to take informed decisions to improve building energy performance in their properties and in their municipalities. These applications, named ENERHAT and ENERPAT, are based on the integration of building data from multiple sources and domains (energy performance certificates, cadastre, geographic information, and census), building refurbishment policies and assessment tools. Data integration has been performed using Semantic Web technologies. A user-friendly interface enables end-users of these on-line applications to obtain information about the current building status of properties, the measures which could be undertaken to improve them, the energy savings achieved and their respective costs.
Analytic approximate solutions for fluid flow in the presence of heat and mass transfer
Authors: Kılıcman Adem , Khan Yasir , Akgul Ali , Faraz Naeem , Akgul Esra , Inc Mustafa
Published: January 2018

This paper outlines a comprehensive study of the fluid-flow in the presence of heat and mass transfer. The governing non-linear ODE are solved by means of the homotopy perturbation method. A comparison of the present solution is also made with the existing solution and excellent agreement is observed. The implementation of homotopy perturbation method proved to be extremely effective and highly suitable. The solution procedure explicitly elucidates the remarkable accuracy of the proposed algorithm.
Invariant approaches for the analytic solution of the stochastic Black-Derman toy model
Authors: Izgi Burhaneddin , Bakkaloglu Ahmet
Published: January 2018

We work on the analytical solution of the stochastic differential equations (SDE) via invariant approaches. In particularly, we focus on the stochastic Black-Derman Toy (BDT) interest rate model, among others. After we present corresponding (1+1) parabolic linear PDE for BDT-SDE, we use theoretical framework about the invariant approaches for the (1+1) linear PDE being done in the literature. We show that it is not possible to reduce BDT-PDE into the first and second Lie canonical forms. On the other hand, we success to find transformations for reducing it to the third Lie canonical form. After that, we obtain analytical solution of BDT-PDE by using these transformations. Moreover, we conclude that it can be reduced to the fourth Lie canonical form but, to the best of our knowledge, its analytical solution in this form is hard to find yet.
Research in entropy wonterland: A review of the entropy concept
Authors: Popovic Marko
Published: January 2018

The entropy concept was introduced in the mid-nineteenth century by Clausius and has been continually enriched, developed, and interpreted by researchers in many scientific disciplines. The use of entropy in a wide range of fields has led to inconsistencies in its application and interpretation, as summarized by von Neuman ?No one knows what entropy really is.? To resolve this problem, thermodynamics and other scientific disciplines face several crucial questions concerning the entropy concept: (1) What is the physical meaning of entropy? (2) Is entropy a subjective or an objective property? (3) How to apply entropy to living organisms? To answer these questions, this paper describes the roots, the conceptual history of this important concept, as well as the path of development and application in various scientific disciplines, including classical thermodynamics, non-equilibrium thermodynamics, statistical mechanics, and life sciences.

 This article has been retracted. Link to the retraction 10.2298/TSCI180730231E
Reflexões sobre o objeto de estudo da política educacional
Authors: Mainardes Jefferson
Published: January 2018

O artigo apresenta reflexões sobre o objeto de estudo da política educacional e como os pesquisadores têm trabalhado com esse objeto. Demonstra-se que o objeto de estudo da política educacional é a análise das políticas produzidas pelo Estado (atos do Estado), as quais são criadas na tentativa de resolver problemas existentes e atender demandas da população. Com base em Dale (2012) argumenta-se que os pesquisadores atingem níveis diferenciados de abstração (descrição, generalização empírica, formulação de conceitos/categorias e geração de teorias), aos quais correspondem a diferentes níveis de abordagem: eventos, mecanismos e estruturas (SAYER, 1984). Conclui-se que os estudos de natureza teórica sobre a pesquisa no campo da política educacional emergem como essenciais no campo, o qual requer mais estudos que desvelem aspectos relacionados aos mecanismos e estruturas da política educacional.
Cultura popular e processos de subjetivação
Authors: Ferreira Dulcinéia de Fátima , Varga István Van Deursen
Published: January 2018

Este texto trata da condição humana no cenário das políticas neoliberais. Toma como problema a política de subjetivação em curso e suas consequências na produção de modos de vida. Enquanto o poder atua sobre a vida cartografamos o brincar boi como uma forma de reativar marcas vivas da tradição, de proliferar sentidos para viver. Aqui compartilhamos linhas de vida. A potência da alegria na cultura popular maranhense, no Bumba-meu-boi de matraca do Maracanã. São pistas de que, apesar do poder que atua sobre a vida querendo paralisar as nascentes do devir, outros mundos são possíveis, outras resistências estão em curso. Ao som da matraca, dos pandeiros, do viver coletivamente, solidariamente, do assumir responsabilidades para que Boi sobreviva, o modo brincante de existir anuncia que a potência da vida resiste.
Trabalho e condição humana na contemporaneidade
Authors: Leite Kelen Christina
Published: January 2018

Este artigo se propõe a situar o trabalho no âmbito dos direitos sociais adquiridos ao longo do século XX, sobretudo no pós-guerra a partir do modo de regulação fordista/keynesianista dando nova forma a sociedade salarial e constituíram a condição em que se davam a relação de trabalho e, portanto, instaurando uma condição humana específica para o período. Tal situação passa por uma reestruturação como consequência da reestruturação da sociedade capitalista a partir da crise dos anos de 1970. Crise essa que afeta os países centrais, mas também os ditos periféricos ou emergentes. Especificamente, trataremos de um dos inúmeros retrocessos vividos recentemente, pelo Brasil, no período pós-golpe palaciano e parlamentar de 2016 que é a reforma trabalhista.
Performance of public tasks by companies of local government units
Authors: Gołębiowski Michał
Published: January 2018

The present article focuses on the issue of the provision of services of general economic interest by companies of local government units. Various parts discuss the basic requirements for entrusting the provision of this type of services to commercial companies, with particular reference to phenomena observed on a practical basis. It also addresses the aspects of diagnosed activities that bear signs of defectiveness, while stressing the importance of practices regarded as model. Collection and summary of conditions for the preparation and ordering the services from the sphere of public tasks was accompanied by the reflection on individual solutions, whose culmination are the observations relating to the recent changes in the national legislation and practice observed in other Member States.
Opinions of the Regional Accounting Chambers regarding the documents on the financial activity of the metropolitan union
Authors: Ofiarska Małgorzata
Published: January 2018

Except for one provision, the Act on RACs does not specify the rules and procedure of issuing the RACs’ opinions on the documents drawn in the course of financial activity of these unions. In this regard, the provisions of the Public Finance Law and Act on RACs apply, setting out the limits of the RACs’ opinion-making activity. The subjects of the opinions are the following: draft resolutions, periodical information and reports, recovery proceedings programmes, other financial documents. In general, the opinions issued by RACs do not contain any content binding for their recipients, but in certain situations specific obligations arise, e.g. to present opinion in a proper term to the proper body, making correction to previously prepared financial documents. In one case the negative opinion revokes the entitlement of the decision-making body of the metropolitan union to adopt the budgetary resolution.
Structural transformation and economic development in the best performing sub-Saharan African states
Authors: Świerczyńska Katarzyna
Published: January 2018

Research background: Economic development in sub-Saharan Africa is of paramount importance, yet it escapes most of the attempts to understand it better in the economic dis-course, and it remains a sensitive issue in politics, contradicting stakeholders at national and international levels. The region still lags behind others in terms of technological advancement and economic development. It has grown  significantly in the precedent decade, but the extent of growth has not sufficiently translated to its development. Determining strategies for sub-Saharan Africa is a scientific challenge, which requires more attention. In the globalized, interconnected reality, solving problems of the South is in the best interest of the North.

Purpose of the article: The aim of this research is to analyze structural changes as factors of economic development in the best performing sub-Saharan African countries on the grounds of new structural economics in order to provide policy implications.   Methods: Namibia, Botswana, South Africa and Gabon were selected as best performing economies in the region. Based on the literature review and the analysis of descriptive statis-tics, profiles of sample countries were set. This in turn allowed to determine the potential explanatory variables for OLS model of economic development. In the model, factors relating to labour productivity, technology and structural change were included. The data was sourced from WDI (World Development Indicators) database, Gretl software was used for computations.

Findings & Value added: This paper contributes to the literature by attempting to explain structural changes in the process of economic development in the sub-Saharan region on the sample of best performing states. The paradigm of new structural economics provided theo-retical grounds for empirical analysis. Based on the results, policy implications were proposed with respect to technology promotion, natural resources management, and quality of institutions. The research was limited by data availability and reliability.
Impacto alimentario de los copépodos calanoideos en el Océano Pacífico colombiano
Authors: Giraldo Alan , Velasco Eliana , Martínez Tulia Isabel
Published: January 2018

Se determinó el impacto alimentario de los copépodos en nueve estaciones localizadas en la Cuenca Pacífica Colombiana durante septiembre de 2006. El contenido de pigmentos entéricos, fue medido espectrofotométricamente en tres fracciones de tamaño: pequeño (300-500 µm), mediano (500-1000 µm) y grande (> 1000 µm); y se estimó la tasa de consumo considerando una tasa de evacuación de 0.702 h-1 que fue establecida previamente de manera experimental. Considerando la abundancia de cada fracción y la concentración de clorofila-a en cada estación, se cuantificó el impacto alimentario como un porcentaje de la biomasa fitoplanctónica disponible. Los copépodos de menor tamaño fueron significativamente más abundantes en la zona de estudio (Kruskal-Wallis H=21.83; p=0.01). Aunque la tasa de ingestión de los copépodos grandes fue significativamente mayor (Kruskal-Wallis H=6.48; p= 0.04), no se detectaron diferencias significativas entre las tasas de consumo de las tres fracciones de tamaño evaluadas (Kruskal-Wallis H=3.07; p=0.21). La clorofila-a integrada (0 – 50 m) en la zona de estudio estuvo entre 4.4 a 9.5 mg Clo-a m-2, siendo el impacto alimentario promedio de los copépodos grandes de 2.57 ± 0.80 %, medianos 3.57 ± 1.89 % y pequeños 12.06 ± 5.99%.
Método BFGS estructurado para la estimulación de máxima verosimilitud
Authors: Arenas Favián , Martínez Héctor Jairo , Pérez Rosana
Published: January 2018

Teniendo en cuenta la estructura especial de la matriz hessiana del logaritmo de la funci´on de verosimilitud an´aloga a la estructura encontrada en problemas de m´ınimos cuadrados no lineales, se propone el m´etodo BFGS estructurado para el problema de la estimaci´on de m´axima verosimilitud y se desarrolla su teor´ıa de convergencia local y q−superlineal siguiendo los lineamientos generales de la teor´ıa de convergencia desarrollada en [12, 13] para m´etodos secante estructurados y la teor´ıa sobre estimaci´onde la m´axima verosimilitud dada en [10]. Adem´as, se realizaron pruebas num´ericas preliminares que muestran el buen comportamiento local del m´etodo propuesto.
Harina de maíz fortificada con polvo de Moringa oleífera: alternativa para la lucha contra el hambre en la población vulnerable
Authors: Del Toro Martínez John J. , Carballo Herrera Arturo Rafael , Rocha Román Leobardo
Published: January 2018

La planta Moringa oleífera, como fue probado por los autores en estudio previo, posee valores significativos de proteína, carbohidratos, minerales y vitaminas. Surge la necesidad de investigar bajo qué medio esta planta puede insertarse en la dieta de la población vulnerable. La metodología empleadapara este estudio se desarrolló mediante la fabricación de harina de maíz fortificada con Moringa. Los dos factores estudiados son: el porcentaje de peso de harina de maíz y el porcentaje de peso de harina de Moringa. Seguidamente, se realizaron ensayos bromatológicos comparativos. Inicialmente, al comparar la harina de Moringa con otras referencias alrededor del mundo, se notó que la cantidad de lípidos, carbohidratos, fosforo, sodio, hierro, magnesio, zinc y vitamina A es significativamente mayor. Además, la fibra cruda y la vitamina B1 son similares. En cuanto a la harina de maíz fortificada con harina de Moringa, se observa, en las mezclas con 20 y 40% de sustitución con harina de hojas deshidratadas de Moringa, que los micronutrientes calcio, fosforo, potasio, sodio, hierro, magnesio, vitamina C y vitamina B2 son significativamente mayores. Igualmente, solo con un 40% de sustitución, la cantidad de proteína (11,6g/100g) y vitamina B1 (1,3mg/100g) resultó significativamente mayor.Como resultado, se tiene el perfil de un nuevo producto con posibilidades de escalamiento industrial y propiedades nutricionales sobresalientes.
Gas Chromatography-Mass Spectrometry Profiles of Ten Pilea Species (Urticaceae)
Authors: Isaza Martínez José Hipólito , Colmenares Ana Julia , Pineda Orozco Victor Manuel , Vásquez V. Ana Isabel
Published: January 2018

The genus Pilea Lindley is the largest among the Urticaceae family. The large size and little commercial interest of this genus make difficult its taxonomy, with few revisions since Weddell.Very few revisions have been reported about the Colombian species since 1939, when Killip made a contribution to the genus for the northern Andes (Ecuador, Peru, Colombia, and Venezuela). To contribute to the knowledge of the Pilea genus in Colombia, field trips were made in the department of Valle del Cauca and ten herbarium samples were analyzed using gas chromatography-mass spectral profiles analysis; which allowed us to identify 33 compounds type monoterpene, sesquiterpene,diterpene, free fatty acids or their methyl, ethyl esters or amides, and triterpenes. It was concluded that Triterpenes were the best chemotaxonomical discriminants for the ten herbarium samples as ten species.
Los orígenes de la geometría: de la necesidad pragmática a la búsqueda apodíctica
Authors: Recalde Luis Cornelio , Murillo Diana Marcela
Published: January 2018

En este artículo se abordan algunos aspectos en torno a la emergencia de la necesidad de demostrar en geometría. A partir de un análisis histórico epistemológico, se sustenta la idea de que el paso de la geometría pragmática de las civilizaciones prehelénicas, al surgimiento de la necesidad de demostrar de los griegos, no fue un cambio instantáneo, sino que floreció como una amalgama de concepciones filosóficas, geométricas y espirituales. Se busca que las reflexiones puedan servir de insumo para los teóricos de la educación matemática y para los docentes, como referencia para plantear estrategias de intervención en el aula.
Lisdexanfetamina em transtornos de humor: uma revisão sistemática
Authors: Silva Anderson Sousa Martins da , Mosconi Isabela Caldas , Cury Michelle Alefe Alves , Palma Sonia Maria Motta
Published: January 2018

Trata-se de uma revisão sistemática da literatura na base de dados MEDLINE para avaliar os efeitos e o perfil de segurança do uso de lisdexanfetamina (LDX) em pacientes com transtorno depressivo (TD) e transtorno afetivo bipolar (TAB), utilizando apenas medical subject headings (MeSH). Foram utilizados os seguintes termos para a busca: “depressive disorder” [MeSH] OR “bipolar disorder” [MeSH] AND “lisdexamfetamine dimesylate” [MeSH]. Somente artigos em português e inglês foram selecionados, sem limitação de período. Como critério de inclusão para o nosso estudo, utilizamos apenas artigos que observaram perfil dos efeitos do uso de LDX em pacientes que apresentavam transtornos do humor, podendo apresentar transtorno de déficit de atenção e hiperatividade comórbido ou não. Foram selecionados oito artigos, mas apenas cinco foram incluídos na síntese narrativa. Encontramos poucos dados sobre o uso de LDX em transtornos do humor, mas os resultados demonstram um uso possível para potencializar o tratamento e reduzir prejuízos cognitivos em pacientes com TD e na melhora dos parâmetros da síndrome metabólica em pacientes com TAB.
Bcl-2 Immunoexpression as Radiotherapy Response Predictor in Undifferentiated Nasopharynx Carcinoma
Authors: Damayanti Beby S. , Afiati . , Hassan Abdul H. , Hernowo Bethy S.
Published: January 2018

Nasopharyngeal carcinoma (NPC) is an epithelial malignancy originating from the surface of the lateral and posterior wall of the nasopharynx. Bcl-2 is an oncoprotein that plays an important role in disrupting the process of apoptosis. Expression of Bcl-2 in biopsy samples of undifferentiated NPC also related to the nature of more aggressive tumor mass and unfavorable clinical radiotherapy response. The purpose of this study was to assess the relationship of Bcl-2 expression with radiotherapy response in undifferentiated NPC. The method of this study areusing 40 samples of paraffin blocks were diagnosed as undifferentiated NPC by histopathologic examination with H&E staining. The samples were divided into 2 groups who respond and do not respond to radiotherapy. All samples examined by Bcl-2 immunohistochemistry and the expression willanalyzed and assess therelationship to radiotherapy response. Of the 40 cases of undifferentiated NPC show imunoekspresi Bcl-2 positive in 39 cases (97.5%) and 1 case (2.5%) negative from response group. The results of statistical analysis of the Bcl-2 obtained significant results with p value <0.05 so we can conclude there is a relationship between Bcl-2 expression with radiotherapy response. Conclusion, Bcl-2 can be used as a predictor for the success of radiotherapy in undifferentiated NPC. Keywords: Bcl-2, undifferentiated NPC, radiotherapy response
Expression of Ki-67 has Correlation with the Degree and Size of Endometriosis Cysts
Authors: Anwar Ruswana , Alif Muhammad , Pribadi Adhi
Published: January 2018

Endometriosis is one of the most common gynecological problem. Cells resulted in chronic inflammation and progressive, proliferative, invasive and even infiltrating an area that resembles the character of the malignancy. Ki-67 is an antigen on the cell nucleus that is found only in actively dividing cells. Expression of Ki-67 are associated with an aggressive tumor and metastasis. This study aims to determine the level of Ki-67 expression correlation with stage and size of the endometriosis cyst. Methods research is observational analytic cross cut method on 56 paraffin blocks of patients who have been diagnosed with endometriosis and had performed a laparotomy or laparoscopic surgery in Dr Hasan Sadikin Hospital. The results showed a significant relationship between the level of expression of Ki-67 with endometriosis cyst size (p <0.001) with a fairly strong relationship (0.55) according to statistics based on criteria Guilford. Moreover the results also showed a significant relationship between the level of expression of Ki-67 with endometriosis stage (p <0.001) with a fairly close relationship (0.564) according to statistics based on criteria Guilford. It can be concluded that the expression of Ki-67 associated with cyst size and stage of endometriosis. Keywords: Ki-67, endometriosis stage, endometriosis cyst
Peer Reviewers of JMH Volume 1 Number 3 February 2016
Authors: Editorial Team Editorial
Published: January 2018

We would like to thank our peer reviewers for the precious contributions in providing clinical,scientific, and methodological expertise for JMH Volume 1 Number 3. We appreciate everythoughtful review of submitted manuscripts and for making important contributions to improve thescientific quality of articles published in JMH. We listed the names in alphabetical order.Dr.dr.Agung Budi,Sp.BSdr. Amaylia Oehadian,Sp.PD-KHOMProf. Dr. Ambrosius Purba, dr.,MS.,AIFOdr.Cherry Azaria, M.Kesdr.Decky Gunawan,M.Kesdr. Djaja Rusmana, M.Si.dr Dono Pranoto, SpB., M.Kesdr. Frecillia Regina,Sp.A.,IBCLCDr. dr. Hana Ratnawati, M.Kes., PA(K)Ingrid S. Surono, PhDProf.dr. Jeanne A. Pawitan, MS, PhDdr. Justin Ginting, Sp.Raddr. Laella Kinghua Liana,Sp.PA,M.Kesdrg. Linda Sari Sembiring, Sp.KGADr. dr. Meilinah Hidayat, M.KesProf. Dr. dr. M. Nurhalim Shahibdrg. Ruslin,Sp.BM.,M.KesProf. Dr. dr. Susy Tjahjani, M.KesProf. dr. Wahyuni Lukita Atmadja, PhD.dr. Yenni Limyati, Sp.KFR.,M.Kes
The Effect of Ethanol Extract from Mangosteen Pericarps towards Parasitemia in Plasmodium berghei-Inoculated Mice
Authors: Marito Debora R. , Tjahjani Susy , Khiong Khie
Published: January 2018

Mangosteen pericarps contains fenolic antioxidant, such as xanthone that acts as free radical scavenging substances and preventing heme polymerization. In this research we evaluated the effect of ethanolic extract of mangosteen pericarps on the parasitemia in Plasmodium berghei-inoculated mice and compared its antimalarial activity with artemisinin monotherapy in reducing the parasitemia in Plasmodium berghei-inoculated mice. Deutschland Denken Yoken (DDY)  mice were randomly divided into 5 groups and inoculated by Plasmodium berghei and given 0.1 mL aquadest (KN), 0.1 mg of artemisinin (KP), 2.5 mg (E1), 0.5 mg (E2) and 0,1 mg (E3) of ethanolic extract from mangosteen pericarps in 0.1 mL aquadest in 3 days. The parasitemia was observed on one day before the treatment, namely on the first day and on the day after the last treatment. We found a highly significant decrease highly significant decrease of the parasitemia in each treatment group compared to the Negative Control group (p < 0.01), and the decrease of parasitemia level in E1 group is similar to the artemisinin monotherapy group (p < 0.05).  Keywords: ethanol extract of mangosteen pericarps, artemisinin, Plasmodium berghei, malaria
Peer Review of JMH Volume 1 Number 5 February 2017
Authors: Team Editorial
Published: January 2018

We would like to thank our peer reviewers for the precious contributions in providing clinical,scientific, and methodological expertise for JMH Volume 1 Number 5. We appreciate everythoughtful review of submitted manuscripts and for making important contributions to improve thescientific quality of articles published in JMH. We listed the names in alphabetical order.dr.Decky Gunawan,M.Kesdr. Djaja Rusmana, M.Sidr.Fari,Sp.THTdr. Fenny, Sp.PKdr. Hanna, M.Kes., PhD., AIFOProf. Dr. Ida Parwati, dr, SpPK(K), PhDProf.dr. Jeanne A. Pawitan, MS, PhDdr. July Ivone,MKK.,M.Pd.KedDr. dr. Meilinah Hidayat, M.Kesdr. Mia Kusmiati,M.Pd.KedDr. dr. Oeij Anindita Adhika, M.Kes., PA(K)Prof.Dr. Ridad Agoes,MPHdr. Rizna T.Rumanti,M.Kesdr. Ronny Lesmana,M.Kes, AIFO, Ph.Ddr. Roro Wahyudianingsih, Sp.PAdr. Sylvia Soeng, M.Kes., PA(K)drg. Vinna Kurniawati. S, M.KesProf. dr. Wahyuni Lukita Atmadja, Ph.D
Factors Related to Cognitive Function in Elderly People
Authors: Mardiyanto Fransiska YD , Jahja Dedeh S , Limyati Yenni
Published: January 2018

Each year in the world, especially in Indonesia, many elderly people exposed to higher risk of dementia due to an increased number of the elderly population and the incidence of mild cognitive impairment in the elderly. The aim of this study is to find out what factors are related with cognitive function in the elderly population. The study used analytic method with cross sectional study design. Subjects were 60 elderly people; male or female ≥ 60 years old. Data were analysed with Chi Square Test (α = 0.05). Cognitive function was measured by MMSE test. The result were found a significant relation between age and cognitive function ( p = 0.014), level of education and cognitive function (p value = 0.000), physical activity and cognitive function (p value = 0.003), cognitive activity and cognitive function (p value = 0.002), and social interaction and cognitive function (p value = 0.000). Gender variable did not have relation with cognitive function (p value = 0.343). This study conclude that there was a relation between age, education level, physical activity, cognitive activity and social interaction with cognitive function in the elderly population. There was no relation between gender and cognitive function in the elderly population.Keywords: cognitive function, cognitive impairment, elderly, MMSE
The Correlation between Fasting Blood Glucose Level with Infiltrated Axillary Limph Node Rate in Infiltrating Ductal Carcinoma of the Breast
Authors: Aribowo Thomas , Soewoto Widyanti
Published: January 2018

Cancer cell have been shown to extensively use glucose for proliferation, even at hypoxia environment. The consumption of glucose in a hypoxia environment induced HIF and VEGF, which play a role in cancer cell infiltration process . The objective of study is to determine the relationship between fasting blood glucose levels with the amount of infiltrated axillary lymph node in patients with infiltrating ductal carcinoma. This is an analytic observational study with cross sectional design. The data obtained were tested with chi-square test (α < 0.05). This study was conducted on 24 infiltrating ductal carcinoma patients. The results showed p value of 0.004, indicating there is a significant correlation between fasting blood glucose levels with the amount of infiltrated axillary lymph nodes. The correlation coefficient ( r) value was 0.505; indicating medium level correlation. As conclusion, there is a significant correlation between fasting blood glucose levels with the amount of infiltrated axillary lymph node in patients with infiltrating ductal carcinoma.Keywords: axillary lymph nodes, breast cancer, fasting blood glucose level, infiltrating ductal carcinoma