bluuebunny/crossref_metadata_2025 huggingface dataset:
Robot-assisted vs laparoscopic lateral transabdominal adrenalectomy: a propensity score matching analysis
Authors: De Crea Carmela , Pennestrì Francesco , Voloudakis Nikolaos , Sessa Luca , Procopio Priscilla Francesca , Gallucci Pierpaolo , Bellantone Rocco , Raffaelli Marco
Published: October 2022

Background

Laparoscopic adrenalectomy (LA) is the gold standard treatment for adrenal lesions. Robot-assisted adrenalectomy (RAA) is a safe approach, associated with higher costs in absence of clear-cut benefits. Several series reported some advantages of RAA over LA in challenging cases, but definitive conclusions are lacking. We evaluated the cost effectiveness and outcomes of robotic (R-LTA) and laparoscopic (L-LTA) approach for lateral transabdominal adrenalectomy in a high-volume center.

Methods

Among 356 minimally invasive adrenalectomies (January 2012–August 2021), 286 were performed with a lateral transabdominal approach: 191 L-LTA and 95 R-LTA. The R-LTA and L-LTA patients were matched for lesion side and size, hormone secretion, and BMI with propensity score matching (PSM) analysis. Postoperative complications, operative time (OT), postoperative stay (POS), and costs were compared.

Results

PSM analysis identified 184 patients, 92 in R-LTA and 92 in L-LTA group. The two groups were well matched. The median lesion size was 4 cm in both groups (p = 0.533). Hormonal hypersecretion was detected in 55 and 54 patients of R-LTA and L-LTA group, respectively (p = 1). Median OT was significantly longer in R-LTA group (90.0 vs 65.0 min) (p < 0.001). No conversion was registered. Median POS was similar (4.0 vs 3.0 days in the R-LTA and L-LTA) (p = 0.467). No difference in postoperative complications was found (p = 1). The cost margin analysis showed a positive income for both procedures (3137 vs 3968 € for R-LTA and L-LTA). In the multiple logistic regression analysis, independent risk factors for postoperative complications were hypercortisolism (OR = 3.926, p = 0.049) and OT > 75 min (OR = 8.177, p = 0.048).

Conclusions

The postoperative outcomes of R-LTA and L-TLA were similar in our experience. Despite the higher cost, RAA appears to be cost effective and economically sustainable in a high-volume center (60 adrenalectomies/year), especially if performed in challenging cases, including patients with large (> 6 cm) and/or functioning tumors.

Graphical abstract
Effect of a 5-aminolevulinic acid gel and 660 nm red LED light on human oral osteoblasts: a preliminary in vitro study
Authors: Pierfelice Tania Vanessa , D’Amico Emira , Iezzi Giovanna , Petrini Morena , Schiavone Valeria , Santalucia Manuela , Pandolfi Assunta , D’Arcangelo Camillo , Piattelli Adriano , Di Pietro Natalia
Published: October 2022

This study aimed to evaluate the effects of a new photodynamic protocol (ALAD-PDT) on primary human osteoblasts (hOBs). The ALAD-PDT protocol consists of a heat-sensitive gel with 5% 5-delta aminolevulinic acid commercialized as Aladent (ALAD), combined with 630 nm LED. For this purpose, the hOBs, explanted from human mandible bone fragments, were used and treated with different ALAD concentrations (10%, 50%, 100% v/v) incubated for 45 min and immediately afterwards irradiated with a 630 nm LED device for 7 min. The untreated and unirradiated cells were considered control (CTRL). The cellular accumulation of the photosensitizer protoporphyrin IX (PpIX), the proliferation, the alkaline phosphatase (ALP) activity, and the calcium deposition were assessed. All concentrations (10, 50, 100%) determined a significant increment of PpIX immediately after 45 min of incubation (0 h) with the highest peak by ALAD (100%). The consequent 7 min of light irradiation caused a slight decrease in PpIX. At 48 h and 72 h, any increment of PpIX was observed. The concentration 100% associated with LED significantly increased hOB proliferation at 48 h (+ 46.83%) and 72 h (+ 127.75%). The 50% and 100% concentrations in combination to the red light also stimulated the ALP activity, + 12.910% and + 14.014% respectively. The concentration 100% with and without LED was selected for the assessment of calcium deposition. After LED irradiation, a significant increase in calcium deposition was observed and quantified (+ 72.33%). In conclusion, the ALAD-PDT enhanced proliferation, the ALP activity, and mineralized deposition of human oral osteoblasts, highlighting a promising potential for bone tissue regeneration.
Autonomous search of an airborne release in urban environments using informed tree planning
Authors: Rhodes Callum , Liu Cunjia , Westoby Paul , Chen Wen-Hua
Published: October 2022

The use of autonomous vehicles for source localisation is a key enabling tool for disaster response teams to safely and efficiently deal with chemical emergencies. Whilst much work has been performed on source localisation using autonomous systems, most previous works have assumed an open environment or employed simplistic obstacle avoidance, separate from the estimation procedure. In this paper, we explore the coupling of the path planning task for both source term estimation and obstacle avoidance in an adaptive framework. The proposed system intelligently produces potential gas sampling locations that will reliably inform the estimation engine by not sampling in the wake of buildings as frequently. Then a tree search is performed to generate paths toward the estimated source location that traverse around any obstacles and still allow for exploration of potentially superior sampling locations.The proposed informed tree planning algorithm is then tested against the standard Entrotaxis and Entrotaxis-Jump techniques in a series of high fidelity simulations. The proposed system is found to reduce source estimation error far more efficiently than its competitors in a feature rich environment, whilst also exhibiting vastly more consistent and robust results.
Technology, Megatrends and Work: Thoughts on the Future of Business Ethics
Authors: D’Cruz Premilla , Du Shuili , Noronha Ernesto , Parboteeah K. Praveen , Trittin-Ulbrich Hannah , Whelan Glen
Published: October 2022

To commemorate 40 years since the founding of the Journal of Business Ethics, the editors in chief of the journal have invited the editors to provide commentaries on the future of business ethics. This essay comprises a selection of commentaries aimed at creating dialogue around the themeTechnology, Megatrends and Work. Of all the profound changes in business, technology is perhaps the most ubiquitous. There is not a facet of our lives unaffected by internet technologies and artificial intelligence. The Journal of Business Ethics established a dedicated section that focuses on Technology and Business Ethics, yet issues related to this phenomenon run right through all the sections. Kirsten Martin, editor of the Technology and Business Ethics section, joins our interim social media editor, Hannah Trittin-UIbrich, to advance a human-centric approach to the development and application of digital technologies that places Business Ethics at centre of the analysis. For Shuili Du, technology is the defining condition for a new era of Corporate Social Responsibility—CSR 3.0—which she defines as “a company’s socially responsible strategies and practices that deal with key ethical and socio-technical issues associated with AI and related technologies on the one hand and leverage the power of AI and related technologies to tackle social and environmental problems on the other hand.” It is not just technologies that are a determining feature of our lives but technology companies, an argument made by Glen Whelan as he examines Big Business and the need for a Big Business Ethics as we try to understand the impact of Big Tech on our post-work world. Indeed, as noted by Ernesto Noronha and Premilla D’Cruz, megatrends in addition to advancement in technologies, namely globalization, the greening of economies, and changes in demographics and migration, are shaping the future for workers in ways previously unimaginable. Contributing to this important debate, Praveen Parboteeah considers the influence of another longstanding but oft overlooked megatrend, the role of religion in the workplace. Given the enormity of the influence of technology and other megatrends in our world, it is not surprising that this essay introduces ground-breaking ideas that speak to the future of business ethics research.
Modular CBT for Childhood Anxiety Disorders: Evaluating Clinical Outcomes and its Predictors
Authors: van Steensel Francisca J. A. , Telman Liesbeth G. E. , Maric M. , Bögels Susan M.
Published: October 2022

This study examined clinical outcomes of a modular individual CBT for children with anxiety disorders (AD), and predictors of outcomes, in usual clinical practice. Participants were 106 children with ADs (7–17 years), and parents. Assessments were pre-, mid-, post-test, and 10 weeks after CBT (follow-up). Predictors (measured pre-treatment) were child characteristics (gender, age, type of AD, comorbid disorders), fathers’ and mothers’ anxious/depressive symptoms, and parental involvement (based on parents’ presence during treatment sessions and the use of a parent module in treatment). At follow-up, 59% (intent-to-treat analyses) to 70% (completer analysis) of the children were free from their primary anxiety disorder. A significant decrease in anxiety symptoms was found. Higher parental involvement was related to lower child anxiety at follow-up, but only for children with comorbid disorders. Findings suggest that it is beneficial to treat anxiety with modular CBT. Future steps involve comparisons of modularized CBT with control conditions.
Adiposity and the risk of dementia: mediating effects from inflammation and lipid levels
Authors: Karlsson Ida K. , Zhan Yiqiang , Wang Yunzhang , Li Xia , Jylhävä Juulia , Hägg Sara , Dahl Aslan Anna K. , Gatz Margaret , Pedersen Nancy L. , Reynolds Chandra A.
Published: October 2022

While midlife adiposity is a risk factor for dementia, adiposity in late-life appears to be associated with lower risk. What drives the associations is poorly understood, especially the inverse association in late-life. Using results from genome-wide association studies, we identified inflammation and lipid metabolism as biological pathways involved in both adiposity and dementia. To test if these factors mediate the effect of midlife and/or late-life adiposity on dementia, we then used cohort data from the Swedish Twin Registry, with measures of adiposity and potential mediators taken in midlife (age 40–64, n = 5999) or late-life (age 65–90, n = 7257). Associations between body-mass index (BMI), waist-hip ratio (WHR), C-reactive protein (CRP), lipid levels, and dementia were tested in survival and mediation analyses. Age was used as the underlying time scale, and sex and education included as covariates in all models. Fasting status was included as a covariate in models of lipids. One standard deviation (SD) higher WHR in midlife was associated with 25% (95% CI 2–52%) higher dementia risk, with slight attenuation when adjusting for BMI. No evidence of mediation through CRP or lipid levels was present. After age 65, one SD higher BMI, but not WHR, was associated with 8% (95% CI 1–14%) lower dementia risk. The association was partly mediated by higher CRP, and suppressed when high-density lipoprotein levels were low. In conclusion, the negative effects of midlife adiposity on dementia risk were driven directly by factors associated with body fat distribution, with no evidence of mediation through inflammation or lipid levels. There was an inverse association between late-life adiposity and dementia risk, especially where the body’s inflammatory response and lipid homeostasis is intact.
The effect of prolonged holding time on the mechanical property and microstructural property of lithium disilicate glass-ceramic
Authors: Lin Feng , Wang Bin , Zhang Yanmei , Li Shuigen , Zhang Qiufang , Xiao Yin , Zuo Qiliang
Published: October 2022

Repeat firing produces uncertainty about stabilizing lithium disilicate glass-ceramic (LDGC) material properties, even though prolonged holding time can enhance the mechanical property of LDGC during a single firing cycle. However, the effect of prolonged holding time and repeat firing on the mechanical property and microstructure of LDGC is not fully understood. In the present study, three groups of LDGC material were created: (i) extension of holding time (7 vs. 14 vs. 28 min) at 780–800 °C; (ii) holding time extension (7 vs. 14 min) and dual sintering at 800–820 °C, respectively; (iii) dual sintering with prolonged holding time (7 vs. 14 min) at 820–840 °C. The nano-indenter test revealed that prolonged holding time (14 and 28 min) promoted the enhancement of LDGC hardness and Young’s modulus. X-ray photoelectron spectroscopy, X-ray diffraction and Fourier transform infrared spectroscopy confirmed that prolonged holding time increased and stabilized LD phase in LDGC, as well as induced residual compressive stress. Scanning electron microscopy showed that prolonged holding time increased LD crystal grains homogeneously and facilitated LDGC to form dense interlocking structure without enlarging crystal size grains significantly. In contrast, LDGC that dual sintered alone at 820–840 °C possessed inferior mechanical properties, coupled with heterogeneous crystal phases, residual tensile stress, and melted crystals grains in the porous microstructure. Interestingly, these deteriorated properties of LDGC caused by dual sintering alone could be counteracted by prolonging the holding time. Nevertheless, the LDGC materials displayed an excellent biocompatibility throughout the study. This study identified that prolonged holding time during repeated firing cycles stabilized LD phase and crystal grain size of LDGC, thus enhanced the mechanical properties, which provided a new insight to extend the repeat fired restoration longevity of LDGC.
Determining our climate policy future: expert opinions about negative emissions and solar radiation management pathways
Authors: Sovacool Benjamin K. , Baum Chad M. , Low Sean
Published: October 2022

Negative emissions technologies and solar radiation management techniques could contribute towards climate stability, either by removing carbon dioxide from the atmosphere and storing it permanently or reflecting sunlight away from the atmosphere. Despite concerns about them, such options are increasingly being discussed as crucial complements to traditional climate change mitigation and adaptation. Expectations around negative emissions and solar radiation management and their associated risks and costs shape public and private discussions of how society deals with the climate crisis. In this study, we rely on a large expert survey (N = 74) to critically examine the future potential of both negative emission options (e.g., carbon dioxide removal) and solar radiation management techniques. We designed a survey process that asked a pool of prominent experts questions about (i) the necessity of adopting negative emissions or solar radiation management options, (ii) the desirability of such options when ranked against each other, (iii) estimations of future efficacy in terms of temperature reductions achieved or gigatons of carbon removed, (iv) expectations about future scaling, commercialization, and deployment targets, and (v) potential risks and barriers. Unlike other elicitation processes where experts are more positive or have high expectations about novel options, our results are more critical and cautionary. We find that some options (notably afforestation and reforestation, ecosystem restoration, and soil carbon sequestration) are envisioned frequently as necessary, desirable, feasible, and affordable, with minimal risks and barriers (compared to other options). This contrasts with other options envisaged as unnecessary risky or costly, notably ocean alkalization or fertilization, space-based reflectors, high-altitude sunshades, and albedo management via clouds. Moreover, only the options of afforestation and reforestation and soil carbon sequestration are expected to be widely deployed before 2035, which raise very real concerns about climate and energy policy in the near- to mid-term.
Dolphins and sea turtles may host zoonotic parasites and pathogenic bacteria as indicators of anthropic pressure in the Gulf of Taranto (Northern Ionian Sea, Central-Eastern Mediterranean Sea)
Authors: Marangi Marianna , Carlucci Roberto , Carlino Piero , Fanizza Carmelo , Cirelli Gianluca , Maglietta Rosalia , Beneduce Luciano
Published: October 2022

The occurrence of protozoan parasites Giardia duodenalis and Cryptosporidium spp. such as the pathogenic bacteria Salmonella spp. and Escherichia coli was molecularly investigated in the following free ranging species of striped dolphins (Stenella coeruleoalba), Risso’s dolphins (Grampus griseus) as well as loggerhead (Caretta caretta) and green (Chelonia mydas) sea turtles living in the Gulf of Taranto (Mediterranean Sea). Out of forty-one investigated individuals belonging to the 4 species, 13 (31.7%) were positive to one or more pathogens and zoonotic G. duodenalis assemblage A, Cryptosporidium parvum and S. enterica were identified in striped dolphins, loggerhead and green sea turtles. In this work, the presence of these opportunistic pathogens has been investigated in fecal samples of free ranging dolphin and sea turtle species for the first time. Moreover, this is the first record of C. parvum in loggerhead sea turtles. These results may provide baseline data for the potential role of cetaceans and sea turtles as potential sentinel species for zoonotic and terrestrial pathogens in the marine environment.
GSN synergies with actin-related transfer molecular chain to promote invasion and metastasis of HCC
Authors: Zhou Yi , He Min
Published: October 2022

Background

Previous studies have shown that the ability of tumor cells to move and migrate is related to the molecular chain pathway mediated by actin. This study focused on the molecular mechanism of gelsolin (GSN) as an important actin-binding protein in promoting HCC invasion and metastasis.

Methods

The relationship between GSN expression and clinical characteristics was observed by immunohistochemistry (IHC). In vitro and in vivo experiments confirmed the role of GSN in HCC metastasis. Dual-immunoprecipitation (IP), immunofluorescence (IF), western blotting, and the gelatinase activity assay were used to investigate the mechanism of GSN-promoting metastasis. PEX fusion proteins were used to intervene in the transfer molecular chain.

Results

Our study found that GSN promoted HCC invasion and metastasis through its synergistic effect with actin-related transfer molecular chain (actin-CD44-MMPs). Concretely, as an important binding molecule of actin, GSN activated MMP2 by interacting with MMP14. Furthermore, CD44 might be a key node in the above-mentioned mechanism. The use of MMP14 domain (PEX fusion protein) to competitively bind to CD44 helped to inhibit the activation of downstream MMP2.

Conclusions

GSN played crucial roles in HCC metastatic process. An improved understanding of the multiple effects of GSN in HCC might facilitate a deeper appreciation of GSN as an important HCC regulator. The study identified GSN and its regulated transfer molecular chain as potential therapeutic targets for HCC.
Thermal activation of kaolinite titanium hydroxide composite for uranium adsorption from aqueous solutions
Authors: Hagag M. S. , Esmaeel Sh. M. A. , Salem F. , Ali A. H. , Zaki S. A.
Published: October 2022

In the present study, thermally treated kaolinite at 600 ºC was incorporated with titanium hydroxide produced from ilmenite to prepare a novel, low-cost and a promising adsorbent (KT). Different analytical techniques such as FTIR, EDS, SEM were used to determine its structural analysis. Its applicability for uranium uptaking and desorption from its aqueous solutions was investigated by varying controlling conditions including pH, shaking time, initial concentrations, temperature and KT dose weight. Untreated kaolinite showed zero loading capacity and adsorption efficiency towards uranium ions, on the contrary thermal activation and incorporation with Ti(OH)4 improved its performance. Batch results for adsorption experiments showed that loading capacity of (KT) reached 160mgg−1; at pH 5, after only 20 min shaking time. Uranium adsorption process was much closer to a traditional Langmuir adsorption isotherm with a theoretical saturation capacity of 161.3mgg−1. From thermodynamics data, the adsorption process is endothermic in nature which emphasized by elevating temperature has an enhancement effect on uranium adsorption with uptake of 205 mgg−1 at 60 ℃. Uranium adsorption was kinetically fitted with the pseudo-second-order model. KT composite has a high applicability and reusability due to its high resistance to extreme acidity levels.
Negative impact of constant RPM control strategy on ship NOx emission in waves
Authors: Ghaemi Mohammad Hossein , Zeraatgar Hamid
Published: October 2022

In severe wave conditions, the ship propulsion system is loaded with high fluctuations due to external disturbances. The highly fluctuating loads enforce radical changes in the main engine torque, which in turn demands variation of the fuel rate injected into the cylinders if a constant rotational speed strategy is applied. Therefore, the temperature of gases varies to a large extent during the combustion process in the cylinders. The emitted NOx is a function of this highly fluctuating temperature. The main goal of this study is to investigate NOx emission under the aforementioned conditions when a usual constant RPM control strategy is applied in waves similar to the calm water condition. The paper presents a mathematical model of the whole system, which is applied to a selected ship both in regular waves and in calm water conditions. The results show that the sea waves, in comparison with the calm water condition, can radically increase the emitted NOx under the constant rotational speed strategy. This change can reach even 1014 times more, averagely. The results also show that the higher the wave height the higher the emitted NOx. It is concluded that the control strategy of keeping the engine rotational speed in waves at a constant level is the most important reason for the significantly increased NOx emission in waves in comparison with the calm water condition.
Trauma- and Violence-Informed Care: Orienting Intimate Partner Violence Interventions to Equity
Authors: Wathen C. Nadine , Mantler Tara
Published: October 2022

Purposeof Review

Intimate partner violence (IPV) is a complex traumatic experience that often co-occurs, or is causally linked, with other forms of structural violence and oppression. However, few IPV interventions integrate this social-ecological perspective. We examine trauma- and violence-informed care (TVIC) in the context of existing IPV interventions as an explicitly equity-oriented approach to IPV prevention and response.

Recent Findings

Systematic reviews of IPV interventions along the public health prevention spectrum show mixed findings, with those with a theoretically grounded, structural approach that integrates a trauma lens more likely to show benefit.

TVIC, embedded in survivor-centered protocols with an explicit theory of change, is emerging as an equity-promoting approach underpinning IPV intervention. Explicit attention to structural violence and the complexity of IPV, systems and sites of intervention, and survivors’ diverse and intersectional lived experiences has significant potential to transform policy and practice.
Gasification of lignite from Polish coal mine to hydrogen-rich gas
Authors: Smolinski Adam , Wochna Sławomir , Howaniec Natalia
Published: October 2022

The efforts of the world research activities involved in clean coal technologies development focus to a considerable extent on integrated hydrogen and power generation technologies based on coal gasification. As an alternative to combustion processes, gasification offers increased efficiency, lower negative environmental impact as well as wider application range of the main product—synthesis gas—in power generation and chemical syntheses. In order to select the most optimal lignite for the purpose of gasification, it is necessary to determine coal reactivity, the key parameter characterizing how fast the fuel reacts with the gasifying medium and controlling its process ability in thermochemical conversion to energy and/or energy carriers. This paper presents the experimental results of oxygen/steam gasification of lignite coal char in a fixed bed reactor under atmospheric pressure and at the temperature of 700, 800 and 900 °C; the samples come from an open pit lignite mine in the southwest of Poland. The effectiveness of the gasification process was tested in terms of the total gas and hydrogen yields, gas composition, carbon conversion rate and chars reactivity.
Priority host plants for Ceratitis capitata, mediterranean fruit fly, based on the host reproduction number for surveillance, trade and eradication programs
Authors: Dominiak B.C. , Taylor-Hukins R.
Published: October 2022

Hosts of tephritids are known to vary in their capacity to support the life cycle from egg lay to adult. This capability is measured by the Host Reproduction Number (HRN) which the number of adults that emerge from one kg of fruit. Mediterranean fruit fly (Medfly) is one of the economically important fruit flies and is distributed worldwide. Many Medfly hosts are known but data to quantify their capacity to support the life cycle is scattered through many reports. Here, we reviewed published literature and found data on 146 potential hosts. We placed them in order of HRN and their Host Suitability Index. The HRN values ranged from bird plum (HRN = 1019) to three species of Syzygium which were non hosts (HRN = 0). The HRN order will help to inform and triage hosts for targeted surveillance and eradication programs and inform disinfestation activities associated with incursion response management, and for trade and risk mitigation.
Unfair commercial practices in a pit market: evidence from an artefactual field experiment
Authors: Bogliacino Francesco , Charris Rafael , Codagnone Cristiano , Folkvord Frans , Montealegre Felipe , Lupiáñez-Villanueva Francisco
Published: October 2022

Commercial practices such as drip pricing, reference pricing and best-price guarantee can be used to set higher prices and mislead consumers, but protective measures can restore efficiency. In a placebo-controlled market experiment, we examined a treatment allowing for the use and misuse of commercial practices. Three additional treatments tested the effects of formal sanctions, informal sanctions and a regret nudge. We found that commercial practices led to higher prices, cheating was systematic and regret nudging was ineffective. Furthermore, formal and informal sanctions reduced both the likelihood of using commercial practices and the likelihood of cheating, leading to welfare increases.
“Wives Wishing to Join Their Husbands”: Colonial Forgery, Gender Legibility, and Labor Migration in West Africa
Authors: Mbah Ndubueze L.
Published: October 2022

European mobilizations of Africans for labor relied on the forgery that Africans can be harnessed into modern units of capitalist production only when organized into households led by wage-earning men supported by domesticated women. Between the 1930s and 1950s, Nigerian male labor migrants to Fernando Po and Gabon, as well as their wives, advanced diverse forgeries in response to the legibility protocols that European states used to control African migrants. Nigerian men used colonial documentation of their status as husbands to claim women’s bodies. Nigerian women used colonial documentation as wives and mothers to mask autonomy, illicit mobility, child trafficking, and sex work. This article develops a historical theory of forgery to explain how colonial legibility protocols and African manipulations of colonial documents constituted gendering practices. It focuses on the diverse documentary strategies women developed to evade colonial surveillance, including photographs to manufacture kinship and colonial court records to generate identities as temporary wives and fictive mothers. As European agents and African men strove to exploit women’s economic and sexual capacities, women used documentary and social forgeries to exploit fissures in colonial rule and create autonomous spaces of mobility and economic opportunity.
Micro-size picosecond-duration fast neutron source driven by a laser–plasma wakefield electron accelerator
Authors: Li Yaojun , Feng Jie , Wang Wenzhao , Tan Junhao , Ge Xulei , Liu Feng , Yan Wenchao , Zhang Guoqiang , Fu Changbo , Chen Liming
Published: October 2022

A pulsed fast neutron source is critical for applications of fast neutron resonance radiography and fast neutron absorption spectroscopy. However, due to the large transversal source size (of the order of mm) and long pulse duration (of the order of ns) of traditional pulsed fast neutron sources, it is difficult to realize high-contrast neutron imaging with high spatial resolution and a fine absorption spectrum. Here, we experimentally present a micro-size ultra-short pulsed neutron source by a table-top laser–plasma wakefield electron accelerator driving a photofission reaction in a thin metal converter. A fast neutron source with source size of approximately 500 μm and duration of approximately 36 ps has been driven by a tens of MeV, collimated, micro-size electron beam via a hundred TW laser facility. This micro-size ultra-short pulsed neutron source has the potential to improve the energy resolution of a fast neutron absorption spectrum dozens of times to, for example, approximately 100 eV at 1.65 MeV, which could be of benefit for high-quality fast neutron imaging and deep understanding of the theoretical model of neutron physics.
Comorbidities associated with 30-day readmission following index coronavirus disease 2019 (COVID-19) hospitalization: A retrospective cohort study of 331,136 patients in the United States
Authors: Nadimpalli Gita , O’Hara Lyndsay M. , Magder Laurence S. , Johnson J. Kristie , Haririan Abdolreza , Pineles Lisa , Goodman Katherine E. , Baghdadi Jonathan D. , Pineles Beth L. , Harris Anthony D.
Published: October 2022

Objective:

Hospital readmission is unsettling to patients and caregivers, costly to the healthcare system, and may leave patients at additional risk for hospital-acquired infections and other complications. We evaluated the association between comorbidities present during index coronavirus disease 2019 (COVID-19) hospitalization and the risk of 30-day readmission.

Design, setting, and participants:

We used the Premier Healthcare database to perform a retrospective cohort study of COVID-19 hospitalized patients discharged between April 2020 and March 2021 who were followed for 30 days after discharge to capture readmission to the same hospital.

Results:

Among the 331,136 unique patients in the index cohort, 36,827 (11.1%) had at least 1 all-cause readmission within 30 days. Of the readmitted patients, 11,382 (3.4%) were readmitted with COVID-19 as the primary diagnosis. In the multivariable model adjusted for demographics, hospital characteristics, coexisting comorbidities, and COVID-19 severity, each additional comorbidity category was associated with an 18% increase in the odds of all-cause readmission (adjusted odds ratio [aOR], 1.18; 95% confidence interval [CI], 1.17–1.19) and a 10% increase in the odds of readmission with COVID-19 as the primary readmission diagnosis (aOR, 1.10; 95% CI, 1.09–1.11). Lymphoma (aOR, 1.86; 95% CI, 1.58–2.19), renal failure (aOR, 1.32; 95% CI, 1.25–1.40), and chronic lung disease (aOR, 1.29; 95% CI, 1.24–1.34) were most associated with readmission for COVID-19.

Conclusions:

Readmission within 30 days was common among COVID-19 survivors. A better understanding of comorbidities associated with readmission will aid hospital care teams in improving postdischarge care. Additionally, it will assist hospital epidemiologists and quality administrators in planning resources, allocating staff, and managing bed-flow issues to improve patient care and safety.
Can't stop eating my feelings: the maladaptive responses of abused employees toward abusive supervision
Authors: Tariq Hussain , Obaid Asfia , Burhan Muhammad , Subhan Muhammad , Babar Sumbal
Published: October 2022

Although organizational research on abusive supervision and its detrimental effects on individuals and organizations has become increasingly popular, little attention has been paid to the maladaptive responses of subordinates to abusive supervision. We build upon self-regulatory theory to investigate one common but overlooked maladaptive response of subordinates to abusive supervision: subordinate overeating behavior. We conducted a single-source, multi-wave daily diary study on 10 consecutive working days (N = 115 employees and 1150 daily surveys) to investigate the relationship between abusive supervision and overeating behavior via a subordinate's negative mood at the high versus low values of subordinate's recovery experiences. We, from the perspective of self-regulatory impairment, found that a subordinate's perceptions of abusive supervision instill a sense of negative mood, which in turn render a loss of control over his/her behavioral intentions toward overeating behavior. Moreover, the first-stage moderation results demonstrated that recovery experiences at the workplace mitigate the depleting effects of abusive supervision. Abused subordinates are less susceptible to the effects of abusive supervision on overeating behavior via their negative moods when there are greater recovery experiences at the workplace. Implications for theory and practice are discussed.
CLASSIFICATION OF ONE DIMENSIONAL DYNAMICAL SYSTEMS BY COUNTABLE STRUCTURES
Authors: BRUIN HENK , VEJNAR BENJAMIN
Published: October 2022

We study the complexity of the classification problem of conjugacy on dynamical systems on some compact metrizable spaces. Especially we prove that the conjugacy equivalence relation of interval dynamical systems is Borel bireducible to isomorphism equivalence relation of countable graphs. This solves a special case of Hjorth’s conjecture which states that every orbit equivalence relation induced by a continuous action of the group of all homeomorphisms of the closed unit interval is classifiable by countable structures. We also prove that conjugacy equivalence relation of Hilbert cube homeomorphisms is Borel bireducible to the universal orbit equivalence relation.
PARTITION FORCING AND INDEPENDENT FAMILIES
Authors: CRUZ-CHAPITAL JORGE A. , FISCHER VERA , GUZMÁN OSVALDO , ŠUPINA JAROSLAV
Published: October 2022

We show that Miller partition forcing preserves selective independent families and P-points, which implies the consistency of
$\mbox {cof}(\mathcal {N})=\mathfrak {a}=\mathfrak {u}=\mathfrak {i}<\mathfrak {a}_T=\omega _2$
. In addition, we show that Shelah’s poset for destroying the maximality of a given maximal ideal preserves tight mad families and so we establish the consistency of
$\mbox {cof}(\mathcal {N})=\mathfrak {a}=\mathfrak {i}=\omega _1<\mathfrak {u}=\mathfrak {a}_T=\omega _2$
.
Citizen science: How to extend reciprocal benefits from the project community to the broader socio-ecological system
Authors: Receveur Aurore , Poulet Lucie , Dalmas Benjamin , Gonçalves Barbara , Vernay Antoine
Published: October 2022

Quantitative plant biology is a growing field, thanks to the substantial progress of models and artificial intelligence dealing with big data. However, collecting large enough datasets is not always straightforward. The citizen science approach can multiply the workforce, hence helping the researchers with data collection and analysis, while also facilitating the spread of scientific knowledge and methods to volunteers. The reciprocal benefits go far beyond the project community: By empowering volunteers and increasing the robustness of scientific results, the scientific method spreads to the socio-ecological scale. This review aims to demonstrate that citizen science has a huge potential (i) for science with the development of different tools to collect and analyse much larger datasets, (ii) for volunteers by increasing their involvement in the project governance and (iii) for the socio-ecological system by increasing the share of the knowledge, thanks to a cascade effect and the help of ‘facilitators’.
The relationship between serum fatty acids and depressive symptoms in obese adolescents
Authors: Seabra da Silva Sandra Maria Chemin , de Piano Ganen Aline , Masquio Deborah Cristina Landi , Dos Santos Quaresma Marcus V.L. , Estadella Debora , Oyama Lila Missae , Tock Lian , de Mello Marco Túlio , Dâmaso Ana Raimunda , do Nascimento Claudia Maria da Penha Oller , Caranti Danielle Arisa
Published: October 2022

Depression and obesity are highly prevalent and are considered inflammatory pathologies; in addition, they are also associated with dietary patterns including types of fatty acids (FA). Changes in the FA composition in the brain are determined by changes in the content and quality of dietary and serum FA. The aim of this study was to verify the relationships between serum-free FA, inflammatory processes and depressive symptoms in obese adolescents. This was a cross-sectional study that analysed a database composed of 138 post-pubertal adolescents. Data regarding the depressive symptoms, body composition, glucose metabolism, lipid profile, FA profile, leptin concentration, as well as adiponectin, IL-A, IL-6, IL-10, TNF-α, C-reactive protein and plasminogen activator inhibitor-1 levels of the subjects were collected. A total of 54·6 % of the adolescents presented with depressive symptoms, and there were positive correlations between depressive symptoms and serum saturated fatty acids (SFA) content, body fat, and inflammatory adipokines, such as leptin, IL-6, and the leptin/adiponectin ratio. Moreover, the content of n-3 polyunsaturated fatty acids (PUFA) was negatively correlated with depressive symptoms, suggesting that eicosatrienoic acid (C20:2n6) and dihomo-γ-linolenic acid (C20:3n-6) are independently associated with depressive symptom scores and can be critical predictors of poor mental health in humans. These results point to the relationship between SFA and depressive symptoms in obese adolescents. However, longitudinal studies are needed to confirm the causality between dietary SFA and depression in obese individuals.
The Oppens: Disability, Disease, and the Authorship of Late Work
Authors: DUNN JOHN
Published: October 2022

Every artist has their last works, but not all are “late works,” as theorized by Edward Said. By revisiting George Oppen’s late poems, I challenge established preconceptions about late-life creativity that have typically emphasized social withdrawal, despair, and finality in his work. Emphasis placed on lateness, I argue, obscures material conditions of textual production, particularly coauthoring literary activities. The Oppens work together to shape a social poetics and model of authoring beyond the normative ideals of self-reliance, especially with Primitive, published when Alzheimer’s disease had all but prevented George from working. The poems and archival evidence of Mary Oppen's editorial work describe the couple's journey through illness and the work's posthumous reinvention as a stylistic artefact.
The potential distribution of Cyclopes didactylus, a silky anteater, reveals a likely unknown population and urgent need for forest conservation in Northeast Brazil
Authors: Fabrício Machado Arielli , Miranda Flávia Regina
Published: October 2022

Cyclopes didactylus, the smallest of all anteaters, inhabits Amazonian and Atlantic forests with an apparently disjunct distribution. Yet, phylogeography reveals historical connections through the forests of the Northeast Region of Brazil. Its populations in this region are classified by the Red List of Threatened Species as Data Deficient and with a trend towards decline. However, Northeast Brazil has a large sampling gap, and the potential distribution of this species has yet to be evaluated. We investigated the potential distribution of C. didactylus to evaluate the hypothesis of a disjunct distribution between Amazonian and Atlantic forests and estimate the amount of protected area in its predicted distribution. We generated a Maxent distribution model using occurrence records, according to the new taxonomic revision of Cyclopes, and selected current bioclimatic variables to evaluate the continuity of the predicted distribution of the species in Northeast Brazil. We also performed past projections to assess historical connections and overlapped maps of protected areas onto their current distribution. Although its distribution is probably disjunct, at least one as-yet-unknown population may be present in the forests of Northeast Brazil, an area poorly protected. The results are useful for targeting field efforts in this under-sampled region.
ePCCr: an online conference organized jointly with the African Light Source and the African Physical Society
Authors: Bourne Susan A.
Published: October 2022

The first Pan-African Conference on Crystallography, PCCr1, was held in Dschang, Cameroon in 2016. This highly successful meeting attracted 192 participants from 32 countries, including 20 African countries. PCCr2 followed in 2019, with over 200 participants from 35 countries. This was a joint meeting with AfLS and was hosted in Accra, Ghana. PPCCr3 was scheduled to take place in Nairobi, Kenya in 2021. Unfortunately, due to the pandemic, this meeting had to be postponed. The Steering Committee of the African Crystallographic Association, along with the Local Organizing Committee of PCCr3, decided to hold an online meeting in order to continue the momentum and sense of community generated during the first two PCCr meetings. ePCCr was, therefore, organized.
Postsecondary L2 writing teachers’ use and perceptions of Grammarly as a complement to their feedback
Authors: Koltovskaia Svetlana
Published: October 2022

Although it has been suggested that automated writing evaluation (AWE) can liberate teachers’ time to focus more on higher-order concerns as it can take care of lower-order concerns, AWE’s impact on teachers’ feedback practice is underexplored. Additionally, scant literature exists on teachers’ perception of AWE when they use it to complement their feedback. This study explored how Grammarly shaped postsecondary L2 writing teachers’ feedback when it was used to complement teacher feedback as well as teachers’ perceptions of the tool. To understand Grammarly’s impact, teachers’ comments on 10 essays were analyzed. The teachers then had a semi-structured interview aimed at exploring their perceptions of Grammarly. The findings showed that teachers provided feedback both on global and local aspects of writing despite using Grammarly as a complement, and there was no division of labor such as that a teacher takes care of higher-order and Grammarly takes care of lower-order concerns. The findings also revealed factors that impacted teachers’ feedback, including teachers’ use of Grammarly reports, their attitudes toward automated feedback, as well as their beliefs about feedback and course objectives. Overall, of the six teachers, four were positive about Grammarly, while two were skeptical. The study provides implications on how to use Grammarly meaningfully as a complement to teacher feedback.
The Transfer of Soviet Prisoners of War from Afghanistan to Switzerland, 1982–1986
Authors: Stadler Liliane
Published: October 2022

After the Soviet invasion of Afghanistan in 1979, the Swiss government initially refused to become diplomatically involved, arguing that as a small, permanently neutral state, Switzerland was unable to make a difference in the Afghan crisis. The present article shows that between 1982 and 1986, the Swiss authorities began to identify the transfer of eleven Soviet prisoners of war from Afghanistan to Switzerland as an opportunity to demonstrate Switzerland's neutral good offices in situations of armed conflict. It also shows that Switzerland's involvement came about primarily through direct and indirect exchanges with non-state actors in the Afghan crisis.
MRI diagnosed cardiac lipoma in tuberous sclerosis: a case report with a very rare association
Authors: Ismail Balaban , Elmalı Muzaffer , Baysal Kemal
Published: October 2022

Tuberous sclerosis is a genetic multisystem disorder characterised by hamartomas in several organs. Cardiac rhabdomyomas are the main features of the disease but lipomas can very rarely be associated. Herein, we present a very rare association of tuberous sclerosis and cardiac lipoma detected by echocardiography and diagnosed as a lipoma via MRI and fat suppression technic, aim to report this very rare association, and emphasise usefulness of MRI in cardiac mass lesions.
Early cardiac dysfunction in obese adolescents with Down syndrome or autism
Authors: Haligheri Geetha , Johnson Tyler , Kathol Melanie , Kuzava Laura , Goth Natalie , Staggs Vincent S. , Donnelly Joseph E. , Ptomey Lauren T. , Forsha Dan
Published: October 2022

Background:

Obesity in adolescents with intellectual and developmental disabilities) occurs at twice the frequency as their typically developing peers. Typically developing adolescents with obesity have abnormal cardiac function (as measured by strain echocardiography) and cardiac mass, but the effects of obesity on cardiac health in adolescents with Down syndrome or autism spectrum disorder are unknown. The purpose of this study was to evaluate the impact of body mass index on cardiac function in adolescents with Down syndrome or autism.

Methods:

Adolescents (age 12–21 years) with Down syndrome (n = 28), autism (n = 33), and age-/sex-matched typically developing controls (n = 15) received an echocardiogram optimised for strain analysis at a single timepoint. Measures of ventricular function, mass, and size were collected. Regression modelling evaluated the impact of body mass index and intellectual and developmental disabilities diagnosis on these cardiac measures.

Results:

In regression modelling, an elevated body mass index z-score was associated with diminished systolic biventricular function by global strain (left ventricular longitudinal strain β 0.87, P < 0.001; left ventricular circumferential strain β 0.57, p 0.003; right ventricular longitudinal strain β 0.63, P < 0.001). Diminished left ventricular diastolic function by early diastolic strain rate was also associated with elevated body mass index (global longitudinal end-diastolic strain rate β −0.7, P < 0.001). No association was found between traditional (non-strain) measures of systolic and diastolic ventricular function and body mass index z-score.

Conclusions:

Obesity in adolescents with Down syndrome or autism negatively impacts cardiac function as measured by echocardiographic strain analysis that was not detected by traditional parameters.