bluuebunny/crossref_metadata_2025 huggingface dataset:
Peran Lembaga Pusat Pelaporan dan Analisis dalam Penaggulangan Tindak Pidana Money Laundring
Authors: Darma I Wayan Panca Eka , Widyantara I Made Minggu , Karma Ni Made Sukaryati
Published: November 2020

The duties, authorities, functions and criminal acts of money laundering in Indonesia are regulated in Law No. 8 of 2010 concerning the Prevention and Eradication of Criminal Acts of Money laundering. This study examines two issues: the role of the PPATK agency in combating money laundering after the enactment of Law No. 8 of 2010 concerning the Prevention and Eradication of Money laundering and criminal sanctions against perpetrators of criminal acts of money laundering in Indonesia. This research uses normative legal method, a process of finding legal rules, legal principles, and legal doctrines in order to answer the legal issues under study from the perspective of statutory regulations. PPATK is an independent agency that has 3 main roles in the prevention and eradication of money laundering, namely: receiving reports on suspicious financial transactions, analysing the reports received from reporting parties, and forwarding the results of report analysis to the authorised party. Article 2 paragraph 1 jo Article 18 of Law Number 31 of 1999 concerning Criminal Acts of Corruption as amended into Law Number 31 of 2001 concerning the Amendment to Law Number 31 of 1999 jo Article 55 paragraph 1 of the Criminal Code. Subsidiarily Article 3 jo Article 18 Law Number 31 of 1999 concerning Eradication of Corruption Crime as amended to Law Number 20 of 2001 concerning the Amendment to Law Number 31 of 1999 jo Article 55 paragraph 1 of the Criminal Code. Secondly, Article 3 paragraph (1) letter g of Law Number 25 of 2003 concerning the Amendment to Law Number 15 of 2002 concerning the Criminal Acts of Money laundering jo Article 55 paragraph (1) of the Criminal Code.
Penegakan Hukum Pidana Internasional dalam Kejahatan Perang terhadap Kemanusiaan
Authors: Muhammad Fadil , Sudini Luh Putu , Sujana I Nyoman
Published: November 2020

War is a condition in which one party subdues its opponent to fulfill his will, a physical or non-physical act between two or more human groups to dominate. The formulation of the problem of this research is how the role of International Criminal Law on law enforcement in war crimes against humanity and how the state responsibility in war crimes against humanity in International Criminal Law. This research method uses the type of normative legal research by doing the assessment based on legal materials of the literature and is a process to find the rule of law, legal principles, and legal doctrines to answer the legal issues faced. War crimes and crimes against humanity are two types of international crimes that exist in twenty international criminal types designed by ILC (International Law Commission) to design the establishment of an international criminal tribunal. The conclusion of this study is  the role of International Criminal Law in  war crimes against humanity can be concluded that is contained in conventions contained in International Humanitarian Law contains only command or prohibition only but international criminal law have role in giving criminal sanction against violation of command or prohibition that and the state's responsibility in international criminal law can be an obligation to prosecute international criminal offenders encountered in various instruments of International Law. The form of state responsibility under the Rome Statute is  that States Parties shall have two main obligations:  States  Parties  shall  bring  each  perpetrator  of  genocide,  crimes  against humanity, criminal acts of war and criminal acts of aggression before the courts and the participating States in imposing their jurisdiction in enforcement of International Criminal Law must cooperate fully in the enforcement of International Criminal Law.
Tanggung Jawab Keperdataan dalam Pengangkutan Udara atas Keterlambatan Jadwal Penerbangan
Authors: Legiman Febriana Samsi , Sudini Luh Putu , Sutama I Nyoman
Published: November 2020

Aviation is a vehicle that is part of transportation that has the ability to move quickly in time, which is able to lift goods and people from one area to another using high capabilities, and requires high safety and security interests in order to help create distribution that is good. steady and smooth. This article aims to find out the civil liability for delays in flights that harming passengers and compensation provided by the carrier to passengers in the event of delay due to default. The type of research used in the writing of this law is normative research. The approach used is the approach of the Act. In practice, airlines are responsible for any losses suffered by passengers in the event of flight delays / delays in the performance of airline duties in accordance with the principle of responsibility based on the element of error. Forms of airline liability against loss suffered by passengers in the event of a flight delays / delay in the implementation of the duties of airlines in the form of burdened return ticket, food and beverage and move passengers to the next flight.
Pemidanaan terhadap Pelaku Tindak Pidana Korupsi Melalui Double Track System
Authors: Putra Anak Agung Gede Budhi Warmana , Nahak Simon , Sugiartha I Nyoman Gede
Published: November 2020

This study aims to seek for deterrent effects for perpetrator of criminal acts of corruption that imposed with Double Track System concept. Double Track System represents the punishment system through two tracks which are criminal sanction and treatment. This study use normative law method. The resource of legal materials which used is primary legal material which is the legal rules and regulations and secondary legal material which is theories of law. The issues explored in this research are legal arrangement for offenders of criminal acts of corruption and punishment system against the offenders. The results showed that about the criminal acts of corruption and sanctions imposed on the offenders are set forth in Act No. 31 of 1999 Jo. Act No. 20 of 2001 about Decrement of Criminal Acts of Corruption and Punishment System and Double Track System against the perpetrators of criminal acts of corruption. The offenders are imposed imprisonment sanctions.
Social comparison orientation and mental health: The mediating role of psychological capital
Authors: Yang Guoliang , Wang Zhihua , Wu Weijiong
Published: November 2020

Little is known about the relationship between social comparison orientation and mental health, especially in the psychological capital context. We proposed a theoretical model to examine the impact of ability- and opinion-based social comparison orientation on mental health using data
from 304 undergraduates. We also examined the mediating effect of the four psychological capital components of hope, self-efficacy, resilience, and optimism in the relationship between social comparison orientation and mental health. Results show that an ability (vs. opinion) social comparison
orientation was negatively (vs. positively) related to the psychological capital components. Further, the resilience and optimism components of psychological capital fully mediated the social comparison orientation–mental health relationship. Our findings indicate that psychological
capital should be considered in the promotion of mental health, and that the two social comparison orientation types have opposite effects on psychological capital.
Архиерейский двор в Тверском кремле: опыт реконструкции
Authors: Salimov Aleksey
Published: November 2020

Епископская кафедра в Твери появилась во второй поло­вине XIII века в период формирования Тверского княжества. Она стала результатом энергичных и весьма дальновидных действий первого тверского князя Ярослава Ярославича, который в середине 60-х - начале 70-х годов XIII века яв­лялся одновременно великим владимирским князем. Тогда же в Тверском кремле началось создание Владычной резиденции, все постройки которой изначально, вероятно, были деревян­ными. Каменные сооружения появились на архиерейском дворе, по всей видимости, в XV веке - практически одновре­менно или несколько позже каменных палат Княжьего двора. В XVI веке на территории владычного комплекса строятся новые каменные здания, фасады которых декорируют полив­ными изразцами по типу тех, что украшали Борисоглебский собор 1558-1561 годов в Старице.

Наивысшего расцвета ансамбль архиерейского двора достигает во второй половине - конце XVII века, когда пода­вляющее большинство построек комплекса возводят в камне. Без особых изменений Владычная резиденция существовала до пожара 1736 года, который коренным образом изменил судьбу позднесредневекового ансамбля. В результате часть каменных палат была разобрана, а новый архиерейский дво­рец возвели на ранее свободном от застройки месте. Позже его отдельные компартименты вошли в состав ныне суще­ствующего Императорского путевого дворца Екатерины II.

Непростая архитектурная история архиерейского двора в Тверском кремле вот уже почти три десятилетия изучается археологами. За эти годы был накоплен значительный матери­ал, который вкупе с другими источниками позволяет в целом определиться с границами и характером застройки городской резиденции тверского архиерея, где среди зданий комплекса находились каменные постройки XV, XVI и XVII веков[1].

 

[1] Работа выполнена по Программе фундаментальных научных исследований Российской академии архитектуры и строительных наук (РААСН)  и Научно-исследовательского института теории и истории архитектуры и градостроительства (филиала ФГБУ «ЦНИИП Минстроя России» НИИТИАГ), а также при поддержке РФФИ, в рамках научного проекта № 19-012-00025.
Организация непрерывного образования в подготовке специалистов направления «Градостроительство»
Authors: Danilina Nina , Vlasov Denis
Published: November 2020

В соответствии с мировыми тенденциями Национальный про­ект Российской Федерации «Образование» определяет формиро­вание системы непрерывного образования как одну из основных стратегических задач развития для образовательных учреждения высшей школы. В статье рассмотрены вопросы развития системы непрерывного образования по направлению подготовки «Градо­строительство», которая включает три существующие ступени образования - бакалавриат, магистратуру и аспирантуру, а также предполагает наличие обширного портфеля программ дополни­тельного образования, который позволит постоянно совершен­ствовать свои навыки или осваивать новые компетенции.В статье предложена модель непрерывного образования, а также подход к организации системы непрерывного образования, основанные на интеграции существующей системы высшего образования, потребностей профессиональной отрасли и современных тен­денций в развитии комфортной и безопасной городской среды. Определены основные виды и способы реализации программ дополнительного образования, которые будут входить в систему непрерывного образования. Апробация представленной модели представлена на образовательном процессе, организованном на кафедре «Градостроительство» НИУ МГСУ и включающем предложения по реализации дополнительной программы про­фессиональной переподготовки «Градостроительство». Про­грамма разработана на базовой кафедре «Градостроительство» НИУ МГСУ и объединяет преподавательский состав кафедры и практикующих специалистов. Программа рассчитана на 350 часов обучения, организованного в дистанционной форме, и включает в себя 12 дисциплин, а также итоговую аттестационную работу. Предложенная программа переподготовки является одной из первых, разработанных в рамках развития дополнительного образования и интегрированных в систему непрерывного об­разования по направлению «Градостроительство».
Devastating iatrogenic internal carotid artery rupture in endoscopic endonasal surgery rescued by a covered stent
Authors: Fu Xiaojie , Quan Tao , Yuan Yongjie , Xu Haowen , Guan Sheng
Published: November 2020

This paper reported a case of devastating iatrogenic ICA rupture in
endoscopic endonasal surgery (EES) rescued by a covered stent. We also
discussed the therapeutic strategies of iatrogenic ICA rupture in EES,
which is of help in the management of this devastating complication.
The butterfly community assemblage of Mowire Quarry Site in the forest agroecological zone of Ghana: Response of indicator biodiversity to ongoing quarry operations.
Authors: Addae Sampson , Addae Sampson , Osae Michael , Harms Danilo , Quartey Jones , Anderson Roger Sigismund , Aikins Ben
Published: November 2020

Quarry operations cause serious environmental impact on invertebrate
communities and contribute negatively to habitat destruction and the
species they promote but very little is still known about the response
of butterflies to such disturbances in western Africa. The current study
provides data from a baseline survey of butterflies at Mowire quarry
site in the agroecological zone of Ghana and investigates the effects of
ongoing quarry operations on butterfly diversity. Specifically quarry
operations were assessed on species abundance and richness. A total of
417 individual butterflies belonging to 67 species from 5 families was
recorded in three zones. High relative abundance in the Eastern Zone
(EZ) (N = 329) and high species richness (S = 55) may be due to
increased flowering plants diversity which contain sweet nectar which
attracts and support rich butterfly abundance. Low species richness (S =
22) and relative abundance (N= 41) in the Western Zone (WZ), and
Northern Zone (NZ) (S = 21) and low relative abundance (N= 47), was
corroborated with low plant diversity. Our results shows that, the EZ
received less negative impact from the quarry operations but the
operations negatively affected WZ and NZ. More generally our study
indicates that state institutions should ensure mandatory environmental
impact assessment reports from the quarry companies.
Are Patients Really Getting What They Want? The Routine Implementation of Decision Aids for Patients with Hip or Knee Osteoarthritis in the High Value Healthcare Collaborative and Alignment between Patient Treatment Choice and Receipt
Authors: Hurley Vanessa
Published: November 2020

Rationale, Aims and Objectives: Alignment between patients’ treatment
choices and treatments received is acknowledged as an important outcome
of shared decision-making (SDM), yet recent research suggests that
patients’ choices do not always align with their actual treatment
trajectories. This paper explores the alignment of patient-expressed
treatment choices (for surgery or medical management) after exposure to
decision aids and treatments received among patients with hip or knee
osteoarthritis within High Value Healthcare Collaborative (HVHC) systems
as the collaborative integrating decision aids intended to support SDM
into routine clinical practice. Method: This retrospective cohort study
examines data from adult (>18 years) patients with hip or
knee osteoarthritis who received decision aids as part of orthopedic
consultations within HVHC systems between 2012-2015. Multivariate
logistic regression explored the association between patient-level
characteristics with the odds of treatment choice-receipt alignment.
Results: The majority of patients with knee osteoarthritis (68.3%) and
hip osteoarthritis (71.9%) received treatments aligned with their
choices following exposure to decision aids, but analyses reveal
important differences in the odds of such alignment across patient
characteristics. In adjusted models, African American patients with knee
osteoarthritis had 50% lower odds of receiving treatment aligned with
their choices compared with white patients (OR = 0.52,
p<0.05). Medicare- or Medicaid-insured knee patients had 49%
and 59% lower odds (respectively) of receiving choice-aligned
treatments relative to privately insured patients. Patients with knee
(OR = 0.40, p<0.01) or hip (OR = 0.75, p<0.05)
osteoarthritis at earlier decision-making stages had lower odds of
receiving treatments congruent with their choices. Conclusion: This work
elucidates the odds of treatment choice-aligned care for patients within
health care systems attempting to routinely integrate decision aids to
support SDM into clinical practice and underscores the gaps in achieving
this alignment among African American patients, those with public
insurance and those at early decision-making stages.
Farmlands Degradation with Intensive Agricultural Practices and Human Health Risk Assessment: A Case Study of Province Punjab, Pakistan
Authors: Nawab Javed , Khan Sardar , Din Zia , Faisal Shah , Ali Abid , Rahman Zia , Alam Mehboob , Khan Amir , Khan Muhammad , Khan Attaullah
Published: November 2020

Farmlands contamination with heavy metals (HMs) can be considered as a
global issue especially in developing countries. The current study
investigates the various pollution indices, potential ecological risk
index (PERI) and human health risk caused by HMs in some selected
regions of Punjab Province, Pakistan. Farmlands soil samples were
collected, acid extracted and analyzed via ICP-MS (Agilent 7500c) for
selected HMs. All the HMs were found within permissible limits set by
worldwide regulatory authorities except Cd which exceeded its limit in
68% agricultural soils of the study area. The CF values for Cd showed
high (CF≥6) degree of contamination to considerable contamination
(3≤CF≤6). The CD values indicated low (CD≤6) contamination to moderate
(6dermal>inhalation. Furthermore, the RI values were
observed higher than 1.0×10–4 for Cd (Lahore and Faisalabad regions)
and Cr (Multan and Faisalabad regions) in children working in farmlands
and likely exposed to high cancer risk. So, minimization of pollutants
must be the top priority of the state to reduce contaminants inputs and
immobilization in soil through environmental protection laws and
regulations
Bachmann bundle impairment following linear ablation of left anterior wall: impact on left atrial function
Authors: Zhang Yanjuan , Wu Fengming , Gao Yu , Wu Nan , Yang Gang , Li Mingfang , Zhou Lei , Xu Di , Chen Ming-long
Published: November 2020

Background: We aimed to evaluate the effect of Bachmann bundle (BB)
impairment on electrical and mechanical function of the left atrium
(LA), as well as the long-term clinical impact of such impairment.
Design: We measured activation time in the five LA walls in 56 patients
with atrial fibrillation. LA reservoir, conduit, and contractile
function were also evaluated. Patients were divided into two groups
based on ablation strategy: the circumferential pulmonary vein isolation
(CPVI) group and CPVI with anterior wall linear ablation (LAWA) group.
Patients in the CPVI+LAWA group were divided into two sub-groups based
on ECG differences following ablation: the BB impairment group and
intact BB group. LA activation time and function were then compared
between the ablation strategy groups and the CPVI+LAWA subgroups.
Results: Patients in the CPVI+LAWA group exhibited longer activation
times in the anterior and lateral walls of the LA, poorer LA synchrony,
and reduced LA contractile and reservoir function when compared with
those in the CPVI group. In the BB impairment subgroup, we observed a
discrepancy between electrical/mechanical remodeling. Among five walls,
activation time was longest in this region. BB impairment was also
associated with reduced LA function. Conclusion: Significant changes in
LA function and conductibility were observed in patients with anterior
wall ablation, especially those with iatrogenic BB impairment.
ANÁLISE DO VESTUÁRIO ESPORTIVO FEMININO SOB A ÓTICA DO PÚBLICO PLUS SIZE: ESTUDO SOBRE ASPECTOS ERGONÔMICOS
Authors: Toledo Daiane De Lourdes , Schmidt Alves Diaz Merino Giselle , Dias Merino Eugênio Andrés , Triska Ricardo
Published: November 2020

Os índices de obesidade no Brasil estão avançando e trazendo diversas implicações para o cotidiano das pessoas. Também há, entretanto, um crescente interesse sobre saúde, bons hábitos alimentares e práticas esportivas. O presente estudo buscou compreender como é a experiência das usuárias plus size com relação ao vestuário esportivo. A pesquisa foi dividida em três etapas, sendo a primeira de levantamento teórico, a segunda aplicada, por meio de entrevistas, e a terceira de redação final. No total, foram 34 participantes, todas do sexo feminino, escolhidas por fazerem parte de um grupo de emagrecimento na cidade de Caçador/SC, o programa “EmagreSer”. Como resultado da avaliação das peças do vestuário, constatou-se que houve pouca diferença na satisfação por parte do público de IMC normal com relação ao público plus size, sendo constatados diversos pontos de melhoria no geral, como: adequação de materiais para maior conforto térmico e hídrico, ajuste da grade de tamanhos para modelagem mais adequada, melhoria da confecção para evitar o desgaste das costuras e, dentre outros, a disponibilização de peças de qualidade com preços acessíveis.
Sounds Good to Me: How Communication Mode and Priming Affect Auditor Performance
Authors: Durkin Mary Parlee , Jollineau S. Jane , Lyon Sarah C.
Published: November 2020

Audit associates routinely interact with clients to request explanations and evidence regarding financial statement account balances. Client explanations may be vague or incomplete. We examine whether auditors' assessments of the quality of client explanations and their decision to follow-up with the client are influenced by (1) communication modes that vary in media richness, and (2) a prime that is intended to stimulate skeptical behavior. Media richness refers to the amount of data inherent in the communication mode. We predict that richer communication modes, such as video, can be more distracting than less rich communication modes, such as email. More distracted auditors will assess the quality of the client's response as higher and are less likely to follow-up with the client—potentially impairing audit quality and increasing audit risk. We predict and find that a prime that focuses auditors on the verifiability of the client's response will mitigate this behavior.
Effect of salvianolic acid B on new bone formation in the orthopedically expanded suture:
Authors: Kayalar Emre , Deynek Gul Tas , Tok Olgu Enis , Kucuk Sevim
Published: November 2020

Objectives

To determine the effects of Salvianolic acid B (Sal B) on new bone formation in the orthopedically expanded premaxillary sutures in rats.

Materials and Methods

The sample consisting of Sprague Dawley rats (male, n = 14) was split in half by random selection: the experiment group (Sal B) and the control group. The premaxillary suture of each rat was expanded by bonding an open-loop spring to two maxillary incisors, each end to one tooth. A 5-day expansion period followed by a 12-day retention period was conducted. The 17-day intraperitoneal administration of Sal B was performed daily for the experiment group at a dose of 40 mg/kilo. The trial was completed after sacrificing the rats and dissection of the premaxillae for histological analysis. The amount of new bone, quantity of capillaries and intensity of inflammatory cells were histomorphometrically determined while the quantities of osteoblasts and osteoclasts were determined immunohistochemically.

Results

The Sal B group was significantly different from the control group and had greater quantities of new bone, capillaries, inflammatory cells, osteoblasts, and osteoclasts.

Conclusions

Salvianolic acid B displays a positive effect during premaxillary expansion with a greater number of capillaries potentially in association with higher bone formation and improved angiogenesis in rats.
Improving Diabetes Control Using Lean Six Sigma Quality Improvement in an Endocrine Clinic in a Large Accountable Care Organization
Authors: Kollipara Usha , Rivera-Bernuy Mario , Putra Joseph , Burks Jessica , Meyer Amber , Ferguson Shayla , Nelson Carolyn , Mutz Jackie , Mirfakhraee Sasan , Bajaj Puneet , Kermani Asra , Fish Jason S. , Ali Sadia
Published: November 2020

This article describes a quality improvement project to reduce the number of patients with diabetes who have poor glycemic control in a large tertiary care endocrinology clinic. The project used the Lean Six Sigma Define-Measure-Analyze-Improve-Control process improvement methodology to develop clinic workflow processes for obtaining A1C measurements in a timely manner to facilitate interventions to improve glycemic control. The percentage of patients with poorly controlled diabetes (A1C >9.0% or missing value in the past 12 months) significantly improved from 26.4% at baseline to 16% (P <0.001), and the proportion of patients with an A1C test within 3–6 months of an appointment improved from 76 to 92%.
Podocyte EGFR Inhibits Autophagy Through Upregulation of Rubicon in Type II Diabetic Nephropathy
Authors: Li Yan , Pan Yu , Cao Shirong , Sasaki Kensuke , Wang Yinqiu , Niu Aolei , Fan Xiaofeng , Wang Suwan , Zhang Ming-Zhi , Harris Raymond C.
Published: November 2020

Renal epidermal growth factor receptor (EGFR)
signaling is activated in models of diabetic nephropathy (DN), and inhibition
of EGFR signaling pathway protects against the development of DN. We have now
determined that in cultured podocytes, high glucose led to increases in activation of EGFR signaling but decreases
in autophagy activity as indicated by decreased beclin-1 and inhibition of LC3B autophagosome formation as
well as increased rubicon (an autophagy inhibitor) and SQSTM1 (autophagy
substrate). Either
genetic (siEGFR) or pharmacologic (AG1478) inhibition of EGFR signaling
attenuated the decreased autophagy activity. In addition, rubicon siRNA
knockdown prevented high glucose-induced inhibition of autophagy in podocytes.
We further examined whether selective
EGFR deletion in podocytes affected the progression of DN in type II diabetes. Selective
podocyte EGFR deletion had no effect on body weight or fasting blood sugars in
either db/db mice or nos3-/-; db/db mice, a model of accelerated type II DN. However selective podocyte EGFR deletion led to relative podocyte
preservation and marked reduction in albuminuria and glomerulosclerosis,
renal proinflammatory cytokine/chemokine expression and decreased pro-fibrotic and fibrotic components in nos3-/-;
db/db mice. Podocyte EGFR deletion led to decreased podocyte
expression of rubicon, in association with increased podocyte autophagy
activity. Therefore, activation of EGFR signaling in podocytes contributes to
progression of DN at least in part by increasing rubicon expression, leading to
subsequent autophagy inhibition and podocyte injury.
Glucagon resistance and decreased susceptibility to diabetes in a model of chronic hyperglucagonemia
Authors: Kramer Nadejda Bozadjieva , Lubaczeuski Camila , Blandino-Rosano Manuel , Barker Grant , Gittes George K. , Caicedo Alejandro , Bernal-Mizrachi Ernesto
Published: November 2020

Elevation of glucagon
levels and increase in a-cell mass are associated with
states of hyperglycemia in diabetes. Our previous studies have highlighted the
role of nutrient signaling via mTOR Complex 1 (mTORC1) regulation that controls
glucagon secretion and a-cell mass. The current studies investigated the effects of activation of nutrient
signaling by conditional deletion of the mTORC1 inhibitor, TSC2, in a-cells (aTSC2KO).
We showed that activation of mTORC1 signaling is sufficient to induce chronic hyperglucagonemia
as a result of a-cell proliferation, cell
size and mass expansion. Hyperglucagonemia in aTSC2KO was
associated with an increase in glucagon content and enhanced glucagon
secretion. This model allowed us to identify the effects of chronic hyperglucagonemia
on glucose homeostasis by inducing insulin secretion and resistance to glucagon
in the liver. Liver glucagon resistance in aTSC2KO mice were characterized by reduced expression of the glucagon
receptor (GCGR), phosphoenolpyruvate carboxykinase
(PEPCK) and genes involved in amino acid metabolism and urea production. Glucagon resistance in aTSC2KO mice was associated with improved glucose levels in Streptozotocin
(STZ)-induced
β-cell destruction and HFD-induced glucose intolerance. These studies demonstrate that chronic hyperglucagonemia can improve
glucose homeostasis by inducing glucagon resistance in the liver.
Glucagon resistance and decreased susceptibility to diabetes in a model of chronic hyperglucagonemia
Authors: Admin Ada , Kramer Nadejda Bozadjieva , Lubaczeuski Camila , Blandino-Rosano Manuel , Barker Grant , Gittes George K. , Caicedo Alejandro , Bernal-Mizrachi Ernesto
Published: November 2020

Elevation of glucagon
levels and increase in a-cell mass are associated with
states of hyperglycemia in diabetes. Our previous studies have highlighted the
role of nutrient signaling via mTOR Complex 1 (mTORC1) regulation that controls
glucagon secretion and a-cell mass. The current studies investigated the effects of activation of nutrient
signaling by conditional deletion of the mTORC1 inhibitor, TSC2, in a-cells (aTSC2KO).
We showed that activation of mTORC1 signaling is sufficient to induce chronic hyperglucagonemia
as a result of a-cell proliferation, cell
size and mass expansion. Hyperglucagonemia in aTSC2KO was
associated with an increase in glucagon content and enhanced glucagon
secretion. This model allowed us to identify the effects of chronic hyperglucagonemia
on glucose homeostasis by inducing insulin secretion and resistance to glucagon
in the liver. Liver glucagon resistance in aTSC2KO mice were characterized by reduced expression of the glucagon
receptor (GCGR), phosphoenolpyruvate carboxykinase
(PEPCK) and genes involved in amino acid metabolism and urea production. Glucagon resistance in aTSC2KO mice was associated with improved glucose levels in Streptozotocin
(STZ)-induced
β-cell destruction and HFD-induced glucose intolerance. These studies demonstrate that chronic hyperglucagonemia can improve
glucose homeostasis by inducing glucagon resistance in the liver.
Parmak Frezeleme Sırasında Takım Salgısının Etkisi Dahil Edilerek Kesme Kuvvetlerinin Tahmini ve Analizi
Authors: AYDIN Mehmet
Published: November 2020

Bu çalışmada, parmak frezelemede kesme kuvvetlerini tahmin etmek için takım salgısının etkilerini içeren bir kesme kuvveti modeli sunulmuştur. Modelde, parmak freze helis açısının etkisini yansıtmak için ekseni boyunca bir dizi disk elemana ayrılmıştır. Kesme kuvvetleri, kuvvet katsayılarının ortalama talaş kalınlığının üstel fonksiyonları olarak tanımlandığı mekanistik model ile her bir zaman aralığında tahmin edilmiştir. Takım salgısının talaş yükü üzerindeki etkisi kesici kenarların gerçek yolu esas alınarak incelenmiştir. Ayrıntılı bir analiz, takım salgısının kesme kuvveti desenini diş geçiş frekansından iş mili dönme frekansına değiştirdiğini göstermektedir. Bu model, Al7075-T6 alüminyum alaşımı için literatürde bulunan deneysel kesme kuvvetlerinin benzetimden elde edilenlerle karşılaştırılmasıyla da doğrulanmış ve kesme kuvvetlerinin tatmin edici bir tahmini sağlamaktadır.
Increase of ventilation systems procurement and installation works efficiency
Authors:   Lviv Polytechnic National University, Department of Heat and Gas Supply and Ventilation, Voznyak Orest , Myroniuk Khrystyna ,   Lviv Polytechnic National University, Department of Heat and Gas Supply and Ventilation, Sukholova Iryna ,   Lviv Polytechnic National University, Department of Heat and Gas Supply and Ventilation, Dovbush Oleksandr ,   Lviv Polytechnic National University, Department of Heat and Gas Supply and Ventilation, Kasynets Mariana ,   Lviv PolytechnicNational University, Department of Heat and Gas Supply and Ventilation
Published: November 2020

The article presents the results of theoretical research on obtaining of the maximum profit by the installation and procurement company in the manufacture and sale of pipe billets for the installation of ventilation systems in the production premise. Graphical and analytical dependences are given. The results of research substantiate the receipt of the maximum profit in the manufacture and sale of the ventilation pipe billets of the different diameters by the installation and procurement enterprise. The purpose of the work is to increase the efficiency of ventilation system installationin production facilities, to determine the maximum profit for the installation and procurement company in the manufacture and sale of pipe billets of the different diameters of ventilation system in the presence of several restrictions on materials and manpower, identify ways to improve installation of ventilation system in production facilities of small volume and justification of the calculation method. Quantitative characteristics of the objective function under given initial conditions are established. The calculated dependences for determining the parameters of the objective function are obtained. The obtained results allow to determine the optimal parameters of the values at the given restrictions on materials and labor intensity of production. The maximum profit in the manufacture and sale of ventilation pipe billets of different diameters by the procurement and installation company is determined. Using of the graphical method and the simplex method to determine the required parameters can significantly increase the efficiency criteria for procurement and installation work and thus reduce the amount of labor and material consumption for the manufacture and installation of ventilation systems.
Thermally conductive cost of the heat-insulating materials
Authors:   Lviv Polytechnic National University, Department of Heat and Gas Supply and Ventilation, Voznyak Orest , Yurkevych Yuriy ,   Lviv Polytechnic National University, Department of Heat and Gas Supply and Ventilation, Sukholova Iryna ,   Lviv Polytechnic National University, Department of Heat and Gas Supply and Ventilation, Dovbush Oleksandr ,   Lviv Polytechnic National University, Department of Heat and Gas Supply and Ventilation, Kasynets Mariana ,   Lviv Polynechnic National University, Department of Heat and Gas Supply and Ventilation
Published: November 2020

The article presents the results of theoretical research to achieve the maximum effect in determination of the economically feasible level of buildings thermal protection. It must be optimal both thermally and economically, an indicator of which there are the costs. Graphical and analytical dependences are given. The research results substantiate the maximum effect when different thermal insulating materials are used. The aim is to increase the efficiency of energy saving measures, reduce their cost by optimizing the cost of thermal energy and insulating materials, determining the optimization criteria and justification for choice the optimal insulating material and its thickness, and determining the optimal thermal resistance, identifying ways to improve energy efficiency and substantiation of the calculation method. One of the most common thermal renovation measures, namely insulation of external walls, is considered. An economic assessment has been conducted, which is an important factor in a certain energy-saving proposition. The solution of the problem is presented, which includes two stages. The result of the first stage is the selection of the optimal heat-insulating material. The second stage is a substantiation of economically expedient thickness of the heatinsulating material. The obtained results make it possible to increase the efficiency of energy saving in thermal renovation of buildings taking into account both energy and economic aspects. In this paper the results of mathematical provement of such factor importance as the thermally conductive cost of the heat-insulating material at their thickness optimization are presented. Determining for the establishment of the normative thermal resistance in the future is the ratio of the cost of thermal energy to the thermal conductivity of the insulating material.
Meningkatkan Aktivitas Belajar Bahasa Indonesia Melalui Model Pembelajaran Pertemuan Kelas Pada Kelas V SDN 3 Pekanbaru
Authors: Sovia Desriana , Nursalim Nursalim
Published: November 2020

This study aims to describe the increase in studen learing activities on Indonesia language lessons through the application of learning models for class meetings  in class V SDN 3 Pekanbaru. The study was mitivated by the low of students’ activities at Indonesian Language subject. The problems ware caused by some factors : the teacher used Monotonous way in teaching, the students were diffuclt in understanding the Subject, the were shy in delivering their ideas, the students were playing With their friend in studying, the students did not focus on studying, and they have Low interest instudy. The formulation of study were whether the use class meeting Learning model increased learning activities of Indonesian language at the fifth Year students of state elementary school 3 Pekanbaru.The study was done into two cycles, the first cycle and the second cycle were done into one meeting. For the success of study the writer arranged the following stages namely: 1) the preparation of action, 2) the implementation of action, 3) observation, 4) reflection.The success of class meeting model was known on the improvement of students’ learning activities in Indonesia language subject prior action at the first cycle and at the second cycle. Students’ learnig activities at prior action was categorized “low” as the number of 59 was in the range 45-64 and the average was 58,9%. At the first cycle students’ learning activities was categorized “enough” as the score 66 was in the range 65-74 and the average was 66,1%. At the second cycle students’ learning activities was categorized “very good” because the number 89 was in the range of 85-100 and the average was 88.7%. this means that class meeting learning model improved students’ learning activities of Indonesia language at the fifth year students of state elementary school 3 Pekanbaru.
Memerkenalkan Sejarah Pahlawan Nasional Ki Sarmidi Mangunsarkoro bagi Peserta Didik MI/SD di Indonesia
Authors: Cahyani Septia Indah , Z Anis Fuadah
Published: November 2020

Behind the independence of the Indonesian State, many things are behind it. Education in Indonesia has existed since ancient times, to be precise in the pre-literacy era. Its development started from the pre-script era, the Hindu-Buddhist kingdom, and Islam until today. Ki Sarmidi Mangunsarkoro is an important factor in the field of education in Indonesia. The Minister of Teaching, Education and Culture, which he occupied, made many changes in Indonesia. The establishment of the Jakarta branch of Taman Siswa made children around them grow interested in reading and provided schools for children from underprivileged families. This study aims to improve students' enthusiasm for learning and to have a sense of struggle for education in Indonesia. The method that can be done is by looking for information about the history of Ki Sarmidi Mangunsarkoro from the history books of the Minister and the Indonesian Cabinet as well as the history books of Ki Sarmidi Mangunsarkoro. The results of this study show that students have a high enthusiasm for learning so that they can continue to the tertiary level and education in Indonesia becomes more advanced. Students have the nature of the view that education is very important. With the history of Ki Sarmidi Mangunsarkoro, there are a lot of knowledge of attitudes and morals that can be taken, one of which is educational.
Illegal use of physical force and special means against prisoners: criminological characteristics and preventive measures
Authors: Smirnov Alexander M.
Published: November 2020

The subject. The article outlines the criminological characteristics of the ilegal use of physical force and special means against persons deprived of their liberty. The purpose of the article is confirmation or confutation of the hypothesis that the reasons for the unlawful use of force methods against convicts are related to the nature of the illegal actions of such convicts. The methodological base of the study was an analysis of 15 cases of unlawful use of physical force and special means by employees of the correctional facilities against imprisoned convicts committed in the period from 2016 to 2019. The author analyzed 12 sentences on bringing employees of the correctional facilities to criminal responsibility for the unlawful use of these forceful methods, as well as a survey of about 190 employees serving in various positions in the correctional facilities where unlawful use of force was carried out. In addition the scientific works of other authors that affect this issue were studied. The main results, scope of application. The criminological characteristics of the illegal use of physical force and special means by employees of the correctional facilities against imprisoned persons are presented. The article includes a description of such victims; a description of the circumstances of use of force; a description of the employees of the correctional facilities who allowed unlawful use of force; the reasons and conditions that contribute to the implementation of this use. Based on the above, some measures are proposed that contribute to the optimal solution of the issue of prevention of the unlawful use of force in the Russian penitentiary practice. Conclusions. The unlawful use of physical forces and special means was carried out against convicts who have destructive moral and psychological qualities, are characterized by a high degree of criminal infection, express a negative attitude towards order and conditions of serving sentences and do not obey the legal requirements of correctional staff. A generalization of the personal characteristics of employees who unlawfully use physical force and (or) special means indicating that they are characterized by positive psychological qualities in general. They strive to be guided by the regulations governing the professional activities of the penal system officer and are positively active in fulfilling their duties. The most probable reasons for the unlawful use of forceful methods of influence against convicts are related to the nature of the unlawful actions of such convicts, provocations, negative features of service due to the specifics of places of deprivation of liberty. Measures taken to prevent the occurrence of negative phenomena in domestic politics can have a positive impact on improving the functioning of the penal correction system, which is in line with legal regulations of a national and international nature.
A koronavírus-válság és a világ régiói
Authors: Botos Katalin
Published: November 2020

A tanulmány megállapítja, hogy a bőség társadalmának más gazdaságelmélet felel meg, mint a szűkösség társadalmának. A keresleti válság már korábban is szükségessé tette a pénzteremtést a vásárlóerő rendelkezésre állásának céljára. A koronavírus okozta válság rámutatott, hogy nemcsak keresleti, de kínálati válság is van. Mindkét területen válságot okoznak az egészségügyi helyzet miatti termelési leállások. A termelési leállás és így a személyes jövedelmek kiesése általános. Az állami beavatkozás szükségszerű, az élet és a megélhetés biztosítása érdekében is. A tanulmány a nemzetközi szakirodalom alapján megvizsgálja a reagálásokat az USA-ban, az EU-ban és a fejlődő országokban. Különös figyelmet fordít a költségvetés és a jegybank együttműködésének kérdésére. Megállapítja, hogy változóban vannak a pénzelmélet dogmái.
A feleslegesre van pénzünk, a szükségesre pedig nincs időnk? : Hozzászólás Árva László és Várhelyi Tamás Elmozdulás a minőségi turizmus felé című tanulmányához
Authors: Banyár József
Published: November 2020

Ahogy Árva László és Vásárhelyi Tamás cikkükben a turizmussal kapcsolatban megfogalmazták, manapság a marketing nagyon sok felesleges igényt generál. Hozzászólásomban ennek okát keresem, s azt találom, hogy ennek legfontosabb oka a feleslegesen hosszú munkaidő. Az így megkeresett jövedelmen pedig egyre több – lényegében felesleges – terméket és szolgáltatást fogunk megvásárolni. Ezekre ráadásul – bizonyos mértékig – rá is szorulunk, mert nem marad időnk másfajta igények kielégítésére, aminek az egész társadalomra és gazdaságra nézve súlyos következményei vannak. Az egyik legfontosabb ilyen a gyermeknevelés.
Tőkealapok és vállalkozó egyetemek a lokális innovációs térben : Lengyel és magyar egyetemek friss tapasztalatai
Authors: Makai Attila Lajos , Rámháp Szabolcs
Published: November 2020

A kockázatitőke-alapok Kelet-Közép-Európában is megfigyelhető rohamos térnyerése jelentős hatással van az innovációs folyamatokra és ökoszisztémákra. Ezzel párhuzamosan a nagyrégióban zajlik a vállalkozó egyetemi modellt előtérbe helyező felsőoktatási átalakulás. A vállalkozó egyetemek és kockázatitőke-alapok a campusokon és a lokális startup-ökoszisztémákban formálják az innováció térbeli megjelenését. A lengyel és magyar egyetem tapasztalatain alapuló összehasonlító elemzés célja kettős. Az egyik cél az oktatási profil hatásainak vizsgálata a vállalkozói egyetemmé válás folyamatára és lépéseire, a másik pedig az egyetemek és kockázatitőke-alapok viszonyának elemzése az egyetemi profil tükrében.
Győr lakásügyi politikája a rendszerváltás után
Authors: Laczkovits-Takács Tímea
Published: November 2020

A tanulmány Győr lakásügyi politikáját és azon belül az önkormányzat által ellátott lakásügyi feladatokat kívánja bemutatni 1990től napjainkig. Az 1990-es rendszerváltás az újonnan megalakult győri önkormányzatot is nagy fokú önállóság és egyúttal óriási feladat elé állította a közszolgáltatások szervezése tekintetében, nem volt ez másként a lakásgazdálkodás területén sem.
AKULTURASI BUDAYA: Studi Kasus Komunitas Samin di Kudus Jawa Tengah
Authors: Rosyid Moh
Published: November 2020

Tujuan penulisan artikel ini untuk mendeskripsikan bentuk akulturasi budaya yang dilakukan komunitas Samin di Kudus, Jawa Tengah terhadap tradisi muslim Nahdliyinyakni tradisi yang merespon kearifan lokal dan tidak bertentangan dengan syariat Islam.Data diperoleh dengan wawancara, kajian literatur, dan observasi. Terkumpulnya data dianalisis dengan pendekatan deskriptif kualitatif. Budaya yang direspon Samin berupa slametan daur kehidupan dan khitan anak lelaki. Akulturasi tercipta simbiosis mutualisme karena Nahdliyin juga responsif terhadap tradisi lokal Jawa. Kekhasan yang masih dipertahankan komunitas Samin adalah memakai celana tokong, ikat kepala, berwarna serba hitam bagi lelaki, dan bagi perempuan memakai jarit. Bila menghadiri perkawinan dan melayat kematian. Bila di rumah atau di sawah memakai pakaian lazimnya warga lain. Ada pula budaya nahdliyin yang tidak direspon Samin karena menghindari keserupaan tradisi, seperti berpeci. Adapun bersarung menjadi tradisi Samin yang hanya digunakan ketika lelaki menikah. Prinsip dasar nahdliyin dalam tradisi adalah tawasuth (moderat), tawazun (keseimbangan antara akidah dengan realita), al I’tidal (tegak lurus, tak mudah terprovokasi), at tasamuh (toleran). Hanya saja, imbas urbanisasi warga Samin, budaya kota menjadi tradisinya pula seperti rambut disemir. Senior Samin pun tidak berdaya menghadapinya. Bila hal ini tidak dikendalikan maka budaya kota mengubah kekhasan Samin.
Scala Conflict Muncă-Familie: Analiza proprietăţilor psihometrice ale versiunii în limba română
Authors: Șulea Coralia , Vîrgă Delia , Galben Nicoleta
Published: November 2020

This study analyzed the factor structure and the psychometric properties of the Romanianversion of the Work-Family Conflict Scale (Carlson, Kacmar & Williams, 2000). Two studies wereconducted (N1=275; N2=424) for verifying, on one hand, factor structure and the psychometricproperties of the scale, and, on the other hand, to evaluate the discriminative validity andrelations with variables of interest. The results confirmed the six-factor structure of the originalscale and also aspects of the discriminative validity. Relations with variables representingattitudinal and organizational consequences were analyzed and theoretical and practicalimplications were presented