bluuebunny/crossref_metadata_2025 huggingface dataset:
PROCESSO DE TRABALHO NA ATENÇÃO BÁSICA NA ASSISTÊNCIA ÀS DOENÇAS CRÔNICAS
Authors: Da Silva Lopes Monique , Pereira Justino Dayane Caroliny , Da Silva Costa Ketyllem Tayanne , Bento de Morais Thiffany Nayara , Barbosa de Andrade Fábia
Published: September 2021

Introdução: O processo de trabalho em saúde tem sido cada vez mais estudado, pois possui uma dimensão subjetiva capaz de interferir na saúde da população. Objetivo: Assim, o presente estudo objetiva avaliar o processo de trabalho desenvolvido na Atenção Básica da região nordeste brasileira voltado para as doenças crônicas, através do resultado apresentado nos dois primeiros ciclos do PMAQ-AB. Metodologia: Trata-se de um estudo exploratório, descritivo. Para tal, foram utilizados dados secundários provenientes do módulo II do PMAQ-AB sobre o processo de trabalho das equipes de Atenção Básica especificamente da região nordeste brasileira. Resultados: Houve melhor adesão dos participantes quantitativamente falando, todavia, menos médicos participaram do segundo ciclo quando comparado com o primeiro. Outro ponto a ser destacado foi a mudança do cenário das taxas de internação e mortalidade por hipertensão arterial sistêmica e diabetes mellitus quando comparado entre os anos estudados. Conclusões: Concluiu-se que há necessidade de uma maior atenção as ações realizadas com os portadores de doenças crônicas na região estudada, pois nota-se que a força de trabalho, quando estimulada e incentivada, pode mudar a realidade local e, consequentemente, os indicadores de saúde.
MODELO LÓGICO PARA OS CICLOS DE MELHORIA DA ESTRATÉGIA SAÚDE DA FAMÍLIA
Authors: De Azevedo Machado Flávia Christiane , Lima Ribeiro Iramara , Alves dos Santos Camila , Henrique Vieira Melo Ricardo , Cristina Dantas da Silva Bianca , Félix Gomes Maria Wégila
Published: September 2021

Introdução: Quando se fala em saúde pública é crucial considerar dados epidemiológicos e métodos de avaliação da assistência, com o intuito de promover melhoria. Uma maneira de propiciar isso são os modelos lógicos, associam atividades, entradas de recursos, saídas de produtos e resultados.  Objetivo: Construir um modelo lógico ilustrativo do funcionamento de uma Unidade de Saúde da Família e validar o seu conteúdo. Metodologia: Foi realizada revisão de literatura, observação participante e conversa com informantes-chave. Ademais, houve validação do conteúdo por profissionais atuantes na Unidade de Saúde da Família (USF) em uma roda de conversa. Resultados: Elaborou-se cinco dimensões (Gestão do Trabalho, Atividades não assistenciais, Atividades assistenciais, Educação permanente continuada e Atividades docentes assistenciais) relacionadas à missão e aos elementos de recursos (físicos, informação, parcerias e financeiros), caracterizando, assim, o modelo. Conclusões: Os impactos alcançados com a aplicação do modelo remetem a critérios de qualidade (legitimidade, empoderamento e resolutividade); ao modelo assistencial instituído (vigilância à saúde); a características do próprio modelo (Clínica ampliada, intersetorialidade, ações multiprofissionais), além da motivação profissional. Todavia, embora validado por USF específica, o modelo orienta-se por uma Política Nacional, podendo contribuir com outras realidades pertinentes à saúde.
Método e a máquina
Authors: Rossi Dorival Campo , Moon Rodrigo Malcom de Barros
Published: September 2021

Este artigo visa debater a ontologia do método a partir da noção de máquinas enquanto produtoras de realidade. Somos dominados pelas mesmas tecnologias que criamos, retroalimentando um aparato que funciona através de nós, que constitui o final da história como concebida por Marx: construída pela humanidade. Realizamos os projetos da modernidade, as potencialidades de nossa cultura ocidental nos provaram ser amedrontadoras. Nossa sociedade foi fabricada segundo regimes de registro, consumo e produção, de tal maneira que o processo nunca para. Quebrar com essa lógica do aparato implica em projetar novas formas e forças que permitam que se projetem novos futuros. Assim, para além do método enquanto ferramenta de trabalho do Real, a deontologia de novos mundos livres de maquinações perversas, do império do método da sociedade pós-industrial, a fim de produzir uma nova história.
Fe3O4@SiO2@CeO2 as a Potential Nanomagnetic Carrier for Oral
Delivery System and Release of Celecoxib
Authors: Razi Maryam Kargar , Ahmadvand Shabnam , Sadeghi Babak , Mirfazli Seyedeh Sara
Published: September 2021

Aims and objectives:

In this study, an attempt was made to synthesize, characterize, and
develop many applications of functionalized rare metal oxide nanoparticles. Herein, a new strategy
for drug delivery is developed to functionalize magnetite nanoparticles to improve their
performances in the delivery of celecoxib.

Materials and methods:

Magnetite Fe3O4@SiO2 nanoparticles are synthesized by the sol-gel
method. The surface of the hydroxyl groups was extended by treating with cerium nitrate salt;
finally, sodium hydroxide was anchored to the surface hydroxyl groups to produce cerium oxidefunctionalized
Fe3O4@SiO2@CeO2 magnetic nanoparticles (FSC). The synthesized sample was
characterized by FT-IR, FESEM, VSM, TGA, and XRD. Afterward, the functionalized
nanoparticles were examined in the delivery of celecoxib as an active drug model involving cerium
oxide and hydroxyl functional groups.

Results:

For this purpose, the amount of loading/release of the drug was investigated in different
amounts of nanocomposite and pH values.

Conclusion:

The results of the present investigation indicate that the formulations (mFSC=5 mg,
pH=3.3) can be considered as best among various formulations with respect to particle size,
entrapment efficiency, and in-vitro successful drug release.
An Inventory of Diagnostic Tools for Detection of COVID-19
Authors: Bhatt Akansha , Fatima Zeeshan , Ruwali Munindra , Hameed Saif
Published: September 2021

The ongoing pandemic of coronavirus disease 2019 (COVID-19) caused by
SARS-COV-2 has afflicted millions of lives globally and disrupted almost all the activities
of mankind. Under such pressing circumstances when no effective therapeutics are
available, a fast and accurate diagnosis of the coronavirus is the only way out to limit the
transmission. Since the inception of COVID-19, the demand for diagnostic tests has
increased day by day and RT-PCR is the commonly used screening test that is not only
time-consuming but requires sophisticated resources. To address the increasing rate of
spread of COVID-19, there is an urgent need for more diagnostic tools as the research
on vaccines is still at a rudimentary level. This review summarizes an inventory of the
diverse and currently available diagnostic methods based on nucleic acid and serology
along with some of those working on novel principles viz. CRISPR, biosensors, and
NGS. Additionally, accessible diagnostic kits that are already approved by the US and
European authorities for the diagnosis of COVID-19 are also suggested that will help in
selecting the most effective tests under the given scenario. Taken together, this review
will pave way for further strengthening the research on the rapid and safer diagnostics of
SARS-COV-2.
Optimization of Phenolic Compound Recovery and Antioxidant Activity of Bay Leaves using Sequential and Response Surface Methodologies
Authors: Khodja Yazid Khaled , Bachir-Bey Mostapha , Ladjouzi Rachid , Khettal Bachra
Published: September 2021

Background:

The laurel is a shrub native to the Mediterranean basin. It is too often wrongly relegated to the kitchen as a simple condiment while it possesses many therapeutic properties and virtues. The valorization of this plant in terms of bioactive compounds seems to be important.

Objective:

The aim of the present study is to optimize total phenolic content (TPC) extraction and antioxidant activity from dried bay leaves using conventional process and response surface methodology (RSM).

Method:

The study of optimization firstly tested three extraction methods (maceration, ultrasonicassisted extraction (UAE), and Microwave-assisted extraction (MAE)) then the best one was considered for RSM.

Results :

The results for the sequential procedure indicated that MAE was the best method for TPC extraction and antioxidant activity of Laurus nobilis leaves. The mathematical modeling of MEA using response surface methodology showed that optimal conditions for phenolic compounds extraction were 57% methanol with microwaves power of 602W during 3.48 minutes. These conditions allowed TPC extraction of 83.53 mg/g and manifested an antioxidant activity of 32.51 mg EAG/g.

Conclusion:

The validation of models indicated that experimental values were in accordance with predicted ones, demonstrating the suitability of developed models and the success of RSM in the optimization of antioxidants extraction from Laurus nobilis leaves. Therefore, the bay leaves could be considered as an interesting source of phenolic antioxidants.
Stem Cell Therapy for the Treatment of Crohn's Disease; Current Obstacles
and Future Hopes
Authors: El-Nakeep Sarah
Published: September 2021

Background:

Crohn's disease (CD) is an autoimmune disease of the gastrointestinal
tract, characterized by relapsing and remitting courses. The disease is debilitating in nature with
three prominent phenotypic clinical presentations; fistulizing, stenosing, and inflammatory. Stem
cells offer new hope for CD patients by modifying the immune response and progression of the
healing process.

Aim:

This mini-review discusses the role of stem cells in treating CD, their effectiveness as a new
therapy and their current limitations.

Methods:

The author conducted a literature review on recent randomized controlled trials and cohort
studies concerned with the topic in question using the following keywords (Crohn's Disease,
perianal fistula, Stem cell therapy, mesenchymal stem cells, remission).

Results:

Clinical trials show that the stem cells are more effective in the CD-associated complex perianal
fistula than the CD enteritis. At present, there are no standardized guidelines regarding dose
of stem cells used, number of doses administered, route of administration, type of stem cells used.
Only one group of researchers proposed a standardized procedure for injecting mesenchymal stem
cells in complex perianal fistula, according to their own experience in clinical trials. Moreover,
mesenchymal stem cells and their related types (placental, adipose tissue, umbilical tissue, etc.) are
the safest and effective in clinical trials. Currently, the commercially available mesenchymal stem
cells preparation (Darvadstrocel (Cx601)) is the only one approved by The United States Food and
Drug Administration (FDA) for clinical use in refractory CD associated complex perianal fistula.

Conclusions:

Stem cell therapy (SCT) shows promise in inducing remission in refractory Crohn's
colitis, and perianal fistula, but further research is required before SCT could be applied to clinical
practice guidelines.
A Differential Evolution Algorithm for Multi-objective Sparse Reconstruction
Authors: Qu Boyang , Zhu Xiaopei , Yan Li , Wen Pengwei , Li Zhao
Published: September 2021

Aims:

This paper proposes a differential evolution algorithm to solve the multi-objective
sparse reconstruction problem (DEMOSR).

Background:

The traditional method is to introduce the regularization coefficient and solve this problem
through a regularization framework. But in fact, the sparse reconstruction problem can be regarded
as a multi-objective optimization problem about sparsity and measurement error (two contradictory
objectives).

Objective:

A differential evolution algorithm to solve multi-objective sparse reconstruction problem
(DEMOSR) in sparse signal reconstruction and the practical application.

Methods:

First of all, new individuals are generated through tournament selection mechanism and
differential evolution. Secondly, the iterative half thresholding algorithm is used for local search to
increase the sparsity of the solution. To increase the diversity of solutions, a polynomial mutation strategy
is introduced.

Results:

In sparse signal reconstruction, the performance of DEMOSR is better than MOEA/D-ihalf
and StEMO. In addition, it can verify the effectiveness of DEMOSR in practical applications for sparse
reconstruction of magnetic resonance images.

Conclusions:

According to the experimental results of DEMOSR in sparse signal reconstruction and the
practical application of reconstructing magnetic resonance images, it can be proved that DEMOSR is
effective in sparse signal and image reconstruction.
Investigating Neuroprotective Potential of Berberine, Levetiracetam and
their Combination in the Management of Alzheimer’s Disease Utilizing
Drug Repurposing Strategy
Authors: Dhaneshwar Suneela , Singh Anuradha , Mazumder Avijit
Published: September 2021

Aim:

The aim of the present work was to evaluate the neuroprotective potential of berberine,
levetiracetam and their combination in lead acetate-induced neurotoxicity by applying a
drug repositioning approach

Background:

Alzheimer's disease (AD) is a neurodegenerative disease characterized by impairment
of memory, disturbances in reasoning, planning, language and perception. Currently, there
are only four drugs approved by US-FDA for AD; therefore, there is an extensive need for new
drug development. The drug repositioning approach refers to the development of new uses for existing
or abandoned pharmaceuticals. Several studies support the neuroprotective abilities of anti-oxidants
resulting in neuronal protection against neurotoxins, suppression of oxidative stress and promotion
of memory, learning and cognitive functions. Many natural polyphenols are being investigated
as a potential therapeutic option for AD. Levetiracetam (LEV), a second-generation antiepileptic
drug, is a new molecule that is clearly differentiated from conventional antiepileptic
drugs by its pharmacologic properties. LEV also has been previously demonstrated to protect
against oxidative stress-induced neurotoxicity in several models of seizures. Berberine (BBR) is an
anti-inflammatory and anti-oxidant phytoconstituent.

Objective:

To study the therapeutic effect of berberine, levetiracetam and their physical mixture in
lead acetate-induced neurotoxicity in Swiss albino mice for probable application in the management
of Alzheimer's disease

Methods:

Neurotoxicity was induced in Swiss albino mice by lead acetate. Behavioural parameters,
such as transfer latency time and percentage alternation, were studied using Morris water
maze (MWM), Elevated plus-maze test (EPM) and Y-maze for the assessment of improvement in
learning and memory. Concentrations of acetylcholinesterase, MDA and GSH in the brain were also
estimated. Brain samples were subjected to histopathological studies.

Results:

Results revealed that the combination of BBR and LEV exhibited a significant neuroprotective
effect by decreasing escape latency time and increasing time spent in the target quadrant in
MWM. The combination also decreases transfer latency time in EPM and acetylcholinesterase levels
in the brain as compared to standard donepezil. Reduced neuronal damage was also confirmed
by the histopathological report.

Conclusion:

Leveteracitam, berberin and their combination resulted in the significant conservation
of various behavioural, biochemical, enzymatic and anti-oxidant parameters that were evaluated.
The neuroprotective effect of plain leveteracitam and berberin was significantly better than their
combination. The anticipated synergism or additive effect was not observed with the combination
of leveteracitam and berberin in lead acetate–induced neurotoxicity.
Pharmaceutical study of Kasisa Satva
Authors: Kailas Kanchan Tejashri , Arati Dubewar
Published: September 2021

Satvapatana and use of Satvabhasma is neglected part not practiced like other therapeutic process
like Bhasmas, Parpati and Sindurakalpana etc. now days we get all Dhatu in its pure form but those
metals are not extracted as therapeutically active material. Those metals are extracted by using
metallurgical methods like leaching, electro wining etc. These methods are not aimed at
therapeutically active agent. Basic principle in Rasashastra is to make Asatmya, toxic metal into
Sharira Satmya Dravya for that from Shodhana to Marana process, we use all organic Sharira Satmya
Dravyas to convert them nonpoisonous, therapeutically active, easily absorbable medicine. These
principals are not involved in contemporary extraction methods. This is major difference in
metallurgical extracted metal and metals extracted in satvapatana process. Rasa Granthas have
mentioned that Satvas are purer, more potent, so here an attempt is done to study the
pharmaceutical process of Satvapatna.
A clinical study to understand Rogastu Dosha
Vaishamyam w.s.r. to Yauvana Pidaka
Authors: . Suraksha , KA Sri Nagesh
Published: September 2021

Saamya-Vaishamya Siddhanta is one of the concepts of Ayurveda which comprises the core subject of
the Ayurveda Shaastra. Svastha Lakshana was considered as Saamyata and this is the standard
health status to be there in human being. Vaishamya is any form of deviation from this status. The
clinical trial was carried out on 30 subjects. Statistical analysis was done within the group before and
after the treatment for subjective and objective parameters. It showed highly significant result both
clinically and staistically.
Comparative evaluation of efficacy of three different
mouthwashes as an adjunct to nonsurgical periodontal
therapy - A double blind clinical study
Authors: Gorwade Nitin , Dhalkari C. D. , Pol Dilip G.
Published: September 2021

Ayurvedic medicine was considered to be world’s oldest medical system, which was originated in India
dating back over thousands of years. There was a long history regarding plants for the improvement
of dental health and oral hygiene. Dentistry, Herbal Medicine, Periodontitis. Current researches
showed that herbal extracts are effective because of the interaction with specific chemical receptors
within the body. Nowadays, there has been a sudden increase in the use of herbal extracts or plant
products as an alternative approach to modern day medicines. This system originated from
Atharvaveda, one of the four Vedas written before 5000 B.C. However its use in dentistry/oral health
is very limited. Therefore the present study was done to evaluate the effeicacy of Triphala and Bakul
in comparison with chlorhexidine as an adjunct to non surgical periodontal therapy.
Phytochemical evaluation of Celastrus paniculatus
seed oil extracted by a method used by ‘Uraanv’
tribe of Chhattisgarh
Authors: Sahu Lalchand , Joshi P. K. , Rout O. P. , Sahu Archana
Published: September 2021

More than 35,000 plant species are being used in various human cultures around the world for
medicinal purposes. Medicated oil plays an important role for prevention and cure of diseases in
Ayurveda. Celastrus paniculatus seed oil is such wonderful medicinally useful oil. It is commonly
known as Black-Oil tree, Intellect tree, Climbing-staff plant and Jyotishmati and “Tree of life” in
Ayurveda. It possesses Anti-depressant, Anti-Parkinson, Anti-Alzheimer’s, Neuroprotective, IQ
improving activity. In tribal district (Jashpur) of Chhattisgarh, Indian people uses traditional method to
extract C. paniculatus oil. It is commonly used by the tribes for the treatment of various diseases like
headache, muscular spasm and local inflammations. The present study aim is documentation of
traditional method of oil extraction used by ‘Uraanv’ tribe. This paper also dealt with the
Physicochemical and qualitative phytochemical evaluation of C. paniculatus seed oil. Oil yield by
traditional method was 25%. Carbohydrate, reducing sugar, monosaccharide, protein, amino acid,
steroid, flavonoid, alkaloid, fixed oil, phytosterols, saponin, diterpenoid and cardiac glycoside were
found in the oil sample.The GC-MS analysis shows the presence of 47 compounds in the oil. These
phytochemical might be responsible for the therapeutic effect of C. paniculatsus seed oil.
Analytical study of Salsaradi Gana Bhawit (three times) Shilajatu
Authors: Kumar Munna , Singh Ajay Kumar , Chaturvedi Uma Shankar , Kumar Mukesh
Published: September 2021

Ayurveda the science of life gives importance to the balance between nature and human relationship; and Rasashastra, one of its associate wings can be considered to hold a key role since it deals in almost all the substances created by nature and marshals then for alleviating the diseases. The therapeutic efficacy of drugs depends upon the genuineness of raw material and right. Shilajeet is an important herbomineral drug among the Maharasa. Describing its importance Charaka has said, “there is hardly any curable disease which cannot be alleviated or cured with the aid of Shilajeet. Aim of study is to evaluate the Physico-chemical parameterof Salsaradi Gana Bhawit Shilajatu. Shilajatu and all raw drugs were obtained from P.G. Department, G.A.C.H. Patna and Shilajeet Shodhana was done by Triphala Kwatha and three times Bhawana by Salsaradigana (Dravyas) Kwatha. All samples were analyzed at Laboratory of Govt. Ayurveda College and Hospital Patna. It found that Shilajatu after Bhawana appeared as semi solid colour brownish black, soft in consistency and having typical smell.
A comparative clinical study on the efficacy of Nasya with Pinyaka / Panchamula Taila and Swalpa Masha Taila in Apabahuka w.s.r. to frozen shoulder
Authors: Costa Conception , A. Sudarshan , Chandran O Jeejo
Published: September 2021

Background: Apabahuka is a Vataja Nanatmaja Vyadhi, in which locomotive functions of Amsa Sandhi are affected mainly due to Vata Dosha Prakopa causing pain, stiffness and restricted movement of the shoulder. Apabahuka can be correlated to Frozen shoulder or Adhesive Capsulitis in modern medicine because of similar symptomatology. Nasya is indicated in Urdhwajatrugata Vikaras. Pinyaka Taila and Swalpa Masha Taila are Vatahara Taila used for Nasya. Method: A single blind randomised clinical study in which 40 clinically diagnosed patients of Apabahuka, fulfilling the inclusion criteria were selected and divided into two groups - Group A treated with Pinyaka / Panchamula Taila Nasya and Group B treated with Swalpa Masha Taila Nasya, comprising of 20 patients each. Result: Statistically Nasya with Pinyaka Taila showed better results in Pain (51.2%), Stiffness (48%), Tenderness (58.33%), with improvement in goniometric readings of shoulder ROM than Nasya with Swalpa Masha Taila in Pain (39.4%), stiffness (40.9%), Tenderness (58%). Discussion: Rukshadi Gunas of Vata are increased in Apabahuka hence Viparita Gunas like Snigdhadi in the form of Brumhana Nasya with Pinyaka Taila was found to be effective in Apabahuka. In the present study Group A Nasya with Pinyaka Taila showed better effect than Group B Nasya with Swalpa Masha Taila.
Role of Phala Ghruta Uttarabasti in the management of female infertility w.s.r to follicular study
Authors: Nidagundi Suvarna P. , Patil Savita S.
Published: September 2021

Background: Streevandhyatva or Female Infertility is a Gynaecological disorder. The etiological factors include the defect in the immature Sperm and Ovum during the fertile period. Incidence rate according to W.H.O is 20-30% is primary while 70-80% of cases are secondary Infertility. Now a day’s maximum number of Female Infertility is due to sedentary lifestyle, Psychological factors, Nutritional deficiency and Stress leads to different condition like PCOD, Obesity, Irregular Menstrual cycle and anovulatory cycle etc. The present study was carried out as a pilot study on 10 subjects of female infertility with the use of Phalagruta Uttarabasti followed by Prakshalana and Pichudharana. Three to five consecutive cycles of Phalagruta Uttarabasti was administered, Posology - Uttarabasti with Phalagruta 5ml daily for 3 days. Diagnostic criteria - Patients are diagnosed based on signs and symptoms like anovulation, PCOD etc., before and after treatment with USG. Results - Among 10 patients, 4 patients - Well response, 2 patients - Improved with follicular study, 3 patients - Poor responded, 1 Patient discontinued the study.
An Observational Study to assess the influence of Ahara on Manasa Bhavas
Authors: TM Chaitra , Pratibha Kulkarni
Published: September 2021

In Bhagawad Gita, the three types of food have been described: they are Satwika, Rajasika and Tamasika it contribute towards the growth of the same temperament in the mind. Manas is one of the factor influenced by Ahara. Manasa Bhavas are defined as physiological states of Mana like Kama, Krodha, Lobha, Moha, Harsha etc. When these Manasa Bhavas are disturbed then they are considered as abnormal and constitute a pathological state of Mana leading to Manasa Vikaras. This study was helpful in assessing the behavior of an individual based on their food habits in turn it can demand us to suggest type of food which can be congenial behavior. It was an Observational study where 160 Subjects were selected as per the inclusion and exclusion criteria Self-validated questionnaire was given to assess the type of Ahara and Manasa Bhava. Chi square test and Cramer’s V value were applied to analyze the level of significance.
A study on the effectivness of Guggulu based Karaveera Ksharasutra in comparison with Apamarga Ksharasutra in the management of Shalyaja Nadivrana w.s.r. to Pilonidal Sinus
Authors: C. J. Monisha , M.G. Narmada
Published: September 2021

Shalyaja Nadivrana is of Agantuja Vranabedha. Nidana Panchaka is described in Sushruta Samhita Nidhana and Chikitsa Sthana. Presence of “Shalya” is hindering factor for healing. Management of Nadivrana includes Ksharasutra ligation. Pilonidal sinus is acquired sinus occurring in young hirsute men’s commonly seen at intergluteal cleft caused by hair penetrating the skin resulting in Pilonidal abscess which gradually forms into sinus with presence of “Hair” leading to wound discharge. It is one of the troublesome diseases which doesn’t respond to medical management till hair is evacuated. The current surgical procedures adopted have surgical risk and recurrence as well. Guggulu and Karaveera is abundantly available and can be preserved easily for long time. Hence can be used as substitute to the standard Ksharasutra. The present study “A study on the effectiveness of Guggulu based Karaveera Ksharasutra in comparison with Apamarga Ksharasutra in the management of Shalyaja Nadivrana w.s.r. to Pilonidal Sinus”was conducted in SJIIM hospital Bengaluru with 40 patients randomly allotted into 2 groups namely - Group A and Group B. Assessment was done based on subjective parameters like (pain, discharge) and objective parameters like (length of tract, tenderness). Observation was done before treatment and on every 7th day till tract is completely cut and healed. Assessment of Pain, discharge, length of tract and tenderness in Group-A showed 100%, 100%, 100% and 100% improvement and in Group-B showed 97.92%, 100%, 100% and 100% respectively. UCT in Group-A is 6.58% and Group-B is 9.15%. Overall results of group A and B is 100% and 99.5% respectively. Statistical analysis revealed that the effectiveness of Guggulu based Karaveera Ksharasutra in Shalyaja Nadivrana is as effective as Apamarga Ksharasutra w.s.r. to pilonidal sinus.
Correlates of overweight and obesity among school going children of Himachal Pradesh
Authors: Chimanchod Minakshi , Chaudhary Vijay , Kumar Abhimanyu
Published: September 2021

Overweight and obesity are important determinants of health leading to adverse metabolic changes and increase the risk of non-communicable diseases. Following the increase in adult obesity, the proportion of overweight and obese children and adolescents has also been increasing. Erroneous life style and food habits are mainly responsible for rising graph of obesity. Hence, the present study was undertaken to study the magnitude of overweight/obesity and its correlates among school-age children ranging from 5-15 years, on the basis of 85th and 95th percentile of body mass index (BMI). Result showed the prevalence of overweight and obesity as 10.33% and 3.33%, respectively. Among number of other correlates related with life style, Kapha predominant Prakriti evolved as an important predictor of obesity. Data of this study clearly delineates that obesity is an increasing malady in rural and semi urban populations also on the pattern of metro cities.
Pharmaceutico analytical study of Ashwagandha Ghrita
Authors: Raveendran Amrita , Rao Sangeeta , S. Vikram
Published: September 2021

Ashwagandha (Withania somnifera (L) Family - Solanaceae) known as Indian ginseng is an effective immunomodulator, aphrodisiac, sedative and adaptogen. Ashwagandha Ghrita is a ghee based Ayurvedic formulation which is available in the market, but Ashwagandha Ghrita containing Rasasindura and Tamra Bhasma along with Ashwagandha and Musta Churna is also mentioned in classical text which many of us are not aware of. As we all know that the action of Rasaushadhis are quick and require very less dose the one mentioned by Vagbhatacharya (author of Rasaratnasamuchaya) is the need of the hour for the immunomodulation. The current trend in applied instrumental medical research encourages good medical practice, clinical and research based drug analysis. The main aim of analytical study is to find out working standards for the formulations and safe use of therapeutics.
Pharmaceutico - Analytical study of Durvadya Taila and its conversion into cream
Authors: Rathod Baban , Asore Gangaprasad , Sankpal Sujata Haribhau
Published: September 2021

Durvadya Taila is medicated oil used in Ayurveda for Kacchu, Vicharchika and Pama (types of Skin diseases) which is caused by vitiated Kapha or Pitta Dosha. Durva is one of the classical drugs of herbal origin, for the management of different disease conditions. The aim of the present study is to do physico-chemical standards for above Durvadya Taila and its conversion into Durvadya Taila Cream. These two formulations have a special importance from pharmaceutical point of view when compared to usual Taila or cream. In present article, we are trying to study analytical results of Durvadya Taila w.s.r. to Durvadya Taila cream. The skin constitutes a major part of the body and serves as a dividing line between the individual and his environment. In the Ayurvedic classics, Bahir Parimarjana means, the medicine intended for external use only. For that purpose, in Ayurveda different forms of external applications are described for the convenience of treatment of different diseases. They are Lepa, Udvartana, Upanaha, Abhyanga, Malahara etc. Without defining creams under Panchavidha Kashaya Kalpana, we can correlate Cream preparation with Lepa or Malahara Kalpana. Creams are those emulsions, which are either oil in-water or water-in-oil type. Durvadya Taila is medicated oil used in Ayurveda for Kacchu, Vicharchika and Pama which comes under Kushtha Rogadhikar.
Clinical evaluation of Amrita Ghrita Sneha-Pana followed by Pippalyadi Yoga Virechana in the management of Vicharchika (chronic dermatitis)
Authors: Tiwari Pritu , Bhattacharjee Abhishek , Krishna Parashara Murali
Published: September 2021

Background: Vicharchika is a Kapha dominated Tridoshaja Kshudra Kustha (minor skin disease) primarily characterized by eruptions with hyperpigmentation, itching and profuse discharge, but sometimes there may be dryness with itching, marked linings and thickening of the skin. The clinical presentation of Vicharchika is very much similar to that of Chronic Dermatitis or Eczema. The incidence of the disease is high and the relapsing nature of the disease makes it difficult to cure. Though many treatment modalities are there but in many of the cases the outcome is not satisfactory and long-term conventional treatment increases the chance of drug induced complications. So, in search of an effective, safe and affordable treatment modality the present study was carried-out. Objective: To evaluate the effectiveness of Amrita Ghrita Sneha-pana followed by Pippalyadi Yoga Virecana in the management of Vicarcika (chronic dermatitis). Materials and Methods: An open level clinical trial with pre-test and post test design were carried out where 30 patients suffering from Vicharchika were registered and were treated with Amrita Ghrita Sneha-pana followed by Virechana with Pippalyadi Yoga. Follow-up was done for 60 days. Assessment was done on 0-day, 15th day, 30th day and 60th day based on the symptoms and standard assessment tool specially designed for Chronic Dermatitis (Eczema). Appropriate statistical methods were used to analyse data. Result: Statistically significant improvement was observed in the symptoms of the disease. Conclusion: Amrita Ghrita Snehapana followed by Pippalyadi Yoga Virecana is found to be effective in the management of Vicharchika.
Antibacterial effectiveness of natural products alone and in combination with Calcium Hydroxide as Intracanal Medicaments : An In-Vitro Microbiological Study
Authors: Bhawalkar Abhilasha , Gulati Shreya , Mulay Sanjyot , Shetty Rajesh
Published: September 2021

Major objective of root canal treatment is disinfection of the root canal system and elimination of microbiota. Various intracanal medicaments as an adjunct to mechanical disinection and irrigation have been used but due to the harmful effects of the commercially available agents, a need for natural alternatives is felt over the time. This in-vitro study aims to evaluate the antibacterial effectiveness of natural agents Septillin and Aloe vera with Calcium hydroxide and without Calcium hydroxide on the Streptococcus mitis, E. Faecalis and Candida albicans using agar well diffusion method. The antibacterial activity was assessed by the diameter of zone of inhibition seen as clear zone around the wells. The study showed that Septillin in combination with Calcium hydroxide and alone showed considerable antimicrobial activity against Streptococcus mitis, Enterococcus faecalis and Candida albicans where as Aloe vera with Calcium hydroxide showed to be mildly effective against all three but not as effective as Septillin and Calcium hydroxide when tested alone.
Assessment of relation between Dhatusarata and Dehabala w.s.r. to Harvard Step Test
Authors: Abhrange Amar Baliram , Abhrange Archana Amar , Waghmare Sachin S.
Published: September 2021

The growth and existence of the human body is dependent on these seven Dhatus. These seven Dhatus are composed of five elements or Panchmahabhutas. Dhatu Sarata or Tissue excellence is a quality assessment of seven Dhatu. Examination of Dhatu Sarata is done at physical and psychological level. For determining the Dhatu Sarata, when the positive features are present above 75 %, it will be considered as best tissue quality (Uttam Sarata). When the positive features are present between 75 % and 25 %, it will be considered as moderate tissue quality (Madhyam Sarata). When positive features are present below 25 %, it will be labeled as poor tissue quality (Heen Sarata). The bodily movements which are meant for producing firmness and strength in the body are known as Vyayama or physical exercises. „Dehabala’ (Physical fitness) of subjects will be determined by Harvard step test. “Harvard Step Test” is a practical application of Ayurvedic Principal that “Bala should be measured by Vyamshakti” (Balam Vyayamshakty Parikshet). The person should be examined with reference to his capacity for exercise which is determined by one‟s ability to perform work. Therefore this study will estimate Dehabala and study the Dhatusarata and their association between them.
An experimental study to evaluate the antidotal activity of Neeli Moola (Indigofera tinctoria) Kalka w.s.r to haematological parameters in Vatsanabha (Aconitum ferox ) induced toxicity
Authors: A Sreelakshmi , R Shrinidhi , Bhat Sudhakar , K Sreejith , Hebbar Chaithra S.
Published: September 2021

Background: Vatsanabha is a potent cardiac poison comes under the category of Mahavisha with its main active principles aconitine, picraconine and pseudaconine. In the literatures there are descriptions about toxicants and in some traditional Malayalam textbooks antidotes has been explained under the concept “Prathyoushadha”. Neeli Moola has been mentioned as a Prathyoushadha for Vatsanabha poisoning in a renowned textbook „Visha Vaidya Jyotsnika‟. Hence to evaluate the antidotal activity in Vatsanabha poisoning, Neeli Moola Kalka has been used and the haematological parameters were analyzed to screen the results. Methods: Wistar strain albino rats were used in this study which were divided into 3 groups, normal control, toxic control and the test drug group. The duration of the study was 28 days .The data generated was mentioned as Mean±SEM. Difference among the groups was assessed by employing one way ANOVA followed by Dunnet‟s mul tiple „t‟ test. Results: Reversible action has been observed after the administration of Neeli Moola Kalka in the hematological parameters which has shown toxicity changes due to administration of Vatsanabha. Conclusion: Neeli Moola Kalka is having mild to moderate antidote effect in Vatsanbha induced toxicity.
Comparative clinical study of Alambushadi Churna and Dwipanchmuladya Tail Basti in the management of Amavata vis-a–vis Rheumatoid Arthritis
Authors: Kumar1 Sunil , Singh J.P. , Singh O.P. , Kumar Mukesh
Published: September 2021

In Ayurvedic text book, Amavata symptom is mentioned as swelling, joint pain, numbness, appetite loss, indigestion and fever. In Charaka Samhita and Sushruta Samhita, Amavata is mentioned as a syndrome called Vatavyadhi, a diverse group of symptoms that are organized according to the systemic and local manifestations of Vata Dosha. According to the Charaka Samhita of Vatavyadhi, when Vata affects the Asthi and Majja there is painful swelling and immobility of the joints. Hence clinical study is planned to evaluate effect of Alambushadi Churna and in the Management of Amavata for that 60 Patients having classical symptomatology of Amavata have been selected from Kayachikitsa OPD and IPD of Sir Sunder Lal Hospital, Institute of Medical Sciences, Banaras Hindu University, Varanasi and divided in two groups. Results of study shows that the sign and symptoms e.g., Loss of appetite, Angamarda, Alasya etc. due to derangement of Aam are observed to be improved in by Alambushadi Churna oral dose compared to Methotrexate.
Clinal study of Pippalyadya Lau in the management of Tamaka Shwasa
Authors: Kapila Amit , Verma Amnish , Bhardwaj Rajni , Sharma Amandeep
Published: September 2021

Our lifestyles have been driven to another level with introduction of new gadgets and science and technological interferences in living in one way or the other. The major cause of poor health conditions are diseases, improper and unhealthy dietary habits, injury, incremented mental stress levels, lack of hygiene, unhealthy lifestyle, etc. The true meaning of being healthy is apposite balance of mental, physical and a spiritual state of a being. Shwasa Roga is classified into 5 categories in Ayurveda. Tamaka Shwasa is one of the categories of Shwasa Roga. In modern Asthma is known as reactive airway disease. This hyper responsiveness manifests itself as broncho constriction following exercise, on natural exposure to strong as irritant fumes such as sulphur dioxide, tobacco smoke, etc. The present study deals with clinical Study of Pippalyadya Lauh on Tamaka Shwasa. In this study total 60 patients of Tamaka Shvasa were registered. Patients were randomly divided under three groups. Results of study reveals that all preparations of Pippalyadi Loha has shown significant results on Tamaka Shwasa patients and Pippalyadi Loha No I and considered to be the best among three different preparations and safe for use.
Too Big for the Library
Authors: Rogerson Terra , Ruane Rogers Monica
Published: September 2021

Outreach is necessary to further the visions and missions of many university libraries, including Manderino Library at California University of Pennsylvania. Organizing events has been used to firmly cement the library’s place in the campus community. However, in the library’s efforts to be part of the larger campus, it has collaborated with other academic departments to create and hold large, well-attended events that require a lot of manpower and hours. After analyzing chat, reference, gate counts, and database usage, librarians found that large and successful events do not increase usage for other library services. This article explores whether the cost is equal to the gain for taking on events that eventually leave the library once they become popular. Results seem to indicate the library might better utilize time and efforts to hold small, focused events, even if attendance is low. Since the bump to actual library services is negligible, the library may want to look at other ways to increase funding instead of continuing to seek out collaborations to offset the cost of attractive events for students. Additionally, we found that while the relationships librarians forge with fellow academic departments are extremely valuable, larger events and collaborations generally relegate librarians to organizer roles that do little for the library’s bottom line.
Reaching Out by Looking Within: The #WellnessWednesdays Initiative at Texas Tech University
Authors: Burns Erin
Published: September 2021

Academic library outreach initiatives that focus on wellness include movement-based fitness programs such as yoga. These programs offer students, staff and faculty who participate a chance to de-stress, lessening the impacts of tension, anxiety, and depression. Academic libraries are suited for these types of programs because we already provide space for other de-stress events, and research of the academic library literature shows that yoga programs in these spaces are increasing. However, the COVID19 pandemic forced changes in outreach programming. In January 2021, Texas Tech University Libraries started offering a yin and restorative yoga program that met weekly in the evenings online via Zoom. Because the university was previously offering these sessions for free to on-campus students, there was a need for a different type of yoga programming that also included online students, as well as staff and faculty. Designated “#WellnessWednesdays”, this program allowed the Texas Tech University Libraries to facilitate yoga sessions for members of the university community by creating a therapeutic environment that is both inclusive and accessible in an online setting.
Organizing and Facilitating Critical Conversations around Systemic Racism: Opportunities and Challenges
Authors: Hackman Melissa , Crowl Paige , Bruchko Erica , DuVernay Jina , Raza Saira
Published: September 2021

The Coffee and Critical Conversations Series was organized by Emory Libraries Diversity, Equity, and Inclusion (DEI) subcommittee on Professional Development for library employees to engage in dialogue and build community around DEI topics. The subcommittee sought to foster understanding and inspire fruitful discussion on institutional racism in libraries, allyship, and the legacy of racialized trauma pervading African American life.

The conversation series began virtually in summer of 2020. Each session was based on a curated collection of shared media (film clips, news articles, TED talks) and was facilitated by volunteers via Zoom. Attendees were given reflection questions to help guide conversation in small breakout groups. As the sessions wrapped up, the facilitators provided further resources for participants to continue their exploration of the topics. We assessed participant responses with an open-ended survey and solicited feedback from participants to inform future sessions.

Like many of our peers, not everyone in our organization has felt informed enough to engage with social justice movements in the library. Our goal was to transform the organizational culture and relieve anxiety around discussing racism and oppression both in our institution and beyond. Coffee and Critical Conversations offers a space for folks to demystify their emotions, find language to express their feelings about current events, and foster authentic connections on our path to creating a more equitable institution.
Health Promotion, Collaboration, and Outreach: Creating Space for Health Literacy at a Specialized, Academic Research Library
Authors: Tringali Billy
Published: September 2021

In the current cultural climate, the ability to engage with and understand health resources is more important than ever. Health literacy, broadly, describes an individual’s ability to process health information and use it to make sound medical choices. In relation, health promotion adapts health literacy to focus on people’s ability to lead healthy lives. While many public librarians are actively engaged in health literacy services to their patrons, far fewer academic librarians report such engagement. This paper aims to demystify health literacy and health promotion for a library audience, along with providing real world examples of collaborating with health experts and turning a library into a built environment that encourages the growth of health literacy skills.
Hiring Student Graphic Designers: Benefits, Challenges, and Lessons Learned
Authors: Jackson John , Hazlitt Jamie
Published: September 2021

This article explores the benefits and challenges of utilizing students as part-time employees to create graphic design materials for academic libraries' promotional needs. The authors describe their experience recruiting students through faculty recommendations, onboarding new hires, and the project management lifecycle for graphic design work.
Letter from the Editors
Authors: CHRISTENSEN SARAH
Published: September 2021

Letter from the Editors
Diagnostic Accuracy of Smartphone-Based Audiometry for Hearing Loss Detection: Meta-analysis
Authors: Chen Chih-Hao , Lin Heng-Yu Haley , Wang Mao-Che , Chu Yuan-Chia , Chang Chun-Yu , Huang Chii-Yuan , Cheng Yen-Fu
Published: September 2021

Background

Hearing loss is one of the most common disabilities worldwide and affects both individual and public health. Pure tone audiometry (PTA) is the gold standard for hearing assessment, but it is often not available in many settings, given its high cost and demand for human resources. Smartphone-based audiometry may be equally effective and can improve access to adequate hearing evaluations.

Objective

The aim of this systematic review is to synthesize the current evidence of the role of smartphone-based audiometry in hearing assessments and further explore the factors that influence its diagnostic accuracy.

Methods

Five databases—PubMed, Embase, Cochrane Library, Web of Science, and Scopus—were queried to identify original studies that examined the diagnostic accuracy of hearing loss measurement using smartphone-based devices with conventional PTA as a reference test. A bivariate random-effects meta-analysis was performed to estimate the pooled sensitivity and specificity. The factors associated with diagnostic accuracy were identified using a bivariate meta-regression model. Study quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies-2 tool.

Results

In all, 25 studies with a total of 4470 patients were included in the meta-analysis. The overall sensitivity, specificity, and area under the receiver operating characteristic curve for smartphone-based audiometry were 89% (95% CI 83%-93%), 93% (95% CI 87%-97%), and 0.96 (95% CI 0.93-0.97), respectively; the corresponding values for the smartphone-based speech recognition test were 91% (95% CI 86%-94%), 88% (95% CI 75%-94%), and 0.93 (95% CI 0.90-0.95), respectively. Meta-regression analysis revealed that patient age, equipment used, and the presence of soundproof booths were significantly related to diagnostic accuracy.

Conclusions

We have presented comprehensive evidence regarding the effectiveness of smartphone-based tests in diagnosing hearing loss. Smartphone-based audiometry may serve as an accurate and accessible approach to hearing evaluations, especially in settings where conventional PTA is unavailable.