bluuebunny/crossref_metadata_2025 huggingface dataset:
Pelatihan Metode Stimulasi dan Intervensi Payudara Terhadap Kelancaran ASI Terhadap Ibu Post Partum Pada Bidan di Wilayah Kerja Puskesmas Tanjung Bintang Lampung Selatan Tahun 2019
Authors: Indrasari Nelly , Roslina Roslina , Nurlaila Nurlaila
Published: November 2022

Cakupan pemberian ASI Eksklusif di Lampung Selatan menetapkan target sebesar 60% dan pencapaian pemberiannya sejak tahun 2013 s.d 2015 pada tahun 2013 sebesar 42%, tahun 2014 sebesar 45,5% dan tahun 2015 sebesar 48% (Profil Kesehatan Dinas Kesehatan Lampung Selatan, 2016). Berdasarkan cakupan pemberian ASI tersebut masih jauh dari target yang ditetapkan Kabupaten Lampung Selatan sendiri dan juga masih jauh sekali dari target nasional sebesar 80%. Cakupan ASI Eksklusif di Kecamatan Tanjung Bintang per tahun 2018 sebanyak 52,85%, dan sampai bulan Mei 2019 sudah tercatat sebanyak 464 bayi (29%) yang berhasil ASI Ekslusif. Dari data Puskesmas Tanjung Bintang per tahun 2019. Salah satu faktor yang mempengaruhi kurangnya cakupan ASI Eksklusif karena keterbatasan  pengetahuan  tenaga kesehatan dalam memberikan pelayanan alternatif (terapi nonfarmakologis) untuk memperlancar ASI, untuk itu diperlukan peningkatan pengetahuan dan keterampilan tenaga kesehatan untuk membantu ibu nifas dalam memperlancar produksi ASI berupa pelatihan kesehatan mengenai Metode Stimulasi Dan Intervensi Payudara dalam memperlancar produksi ASI. Kegiatan pengabdian kepada masyarakat bertujuan meningkatkan pengetahuan dan keterampilan bidan tentang Metode Stimulasi dan Intervensi Payudara sebagai terapi nonfarmakologis untuk memperlancar produksi ASI sehingga dapat membantu menurunkan risiko dan angka kejadian bendungan ASI pada ibu nifas dan dapat meningkatkan cakupan ASI Eksklusif di Puskesmas Tanjung Bintang Kabupaten Lampung Selatan. Pelaksanaan pelatihan ini dimulai dengan melakukan survey lapangan dan koordinasi dengan pihak Kepala Puskesmas, Bidan Koordinator Puskesmas terkait dan IBI Ranting Tanjung Bintang, dilanjutkan dengan sosialisasi program dan pelaksanaan kegiatan. Dalam proses pelaksanaan, kegiatan yang dilakukan adalah pretest, pelatihan, dan posttest. Pelatihan yang dilakukan selama 3 hari ini diikuti oleh 20 orang Bidan Puskesmas Tanjung Bintang. Monitoring dan Evaluasi kegiatan yang bertujuan untuk melihat perkembangan dan keberhasilan pelatihan serta mengevaluasi hasil pelaksanaan kegiatan. Dari kegiatan monitoring penerapan hasil pelatihan yang telah dilakukan dapat disimpulkan bahwa semua peserta sudah menerapkan hasil pelatihan dan sudah 100% ibu nifas diberikan pelayanan stimulasi dan intervensi meskipun belum semua ibu nifas mendapatkan pelayanan Brestcare dan Pijat Oksitosin secara bersamaan.
Pendampingan Desa Tamansari Kecamatan Gedong Tataan Kabupaten Pesawaran Menuju Desa Open Defecation Free (ODF)
Authors: Yushananta Prayudhy , Ahyanti Mei , Hasan Amrul
Published: November 2022

Problema cukup besar di negara sedang berkembang dan menyebabkan kesakitan bahkan kematian yang cukup tinggi adalah penyakit menular, salah satunya adalah diare yang bersifat "healthy Carrier" menimbulkan kesukaran dalam pemberantasannya. Banyak faktor pendorong terjadinya diare, yaitu faktor host, agent, lingkungan dan perilaku. Di Provinsi Lampung terdapat beberapa wilayah yang masih memiliki masalah dalam hal pembuangan tinja dan penyakit diare. Salah satunya adalah Desa Tamansari Kecamatan Gedong Tataan Kabupaten Pesawaran. Selama ini pembuangan tinja langsung dibuang ke dalam aliran sungai yang melintasi desa tersebut. Desa Tamansari merupakan desa yang masuk ke dalam program ODF. Solusi untuk mengatasi permasalahan Desa Tamansari adalah pembangunan intalasi WC dan perubahan perilaku masyarakat dalam membuang tinja. Kegiatan Pengabdian ditujukan sebagai pendampingan masyarakat dalam pembangunan jamban dan perubahan perilaku hidup bersih dan sehat, dilaksanakan pada Bulan September hingga Desember 2018. Pada kegiatan ini, telah terbangun 6 sarana jamban keluarga di Dusun Pasir Erih Desa Taman Sari Kecamatan Gedong Tatan Kabupaten Pesawaran. Jamban yang mudah diakses oleh masyarakat ini telah dimanfaatkan dan dipelihara dengan baik.
Sosialisasi Gizi Seimbang Makanan Lokal (Seruit) Untuk Ibu Hamil Pada Bidan dan Kader Kesehatan di Kabupaten Tulang Bawang Barat
Authors: Sudarmi Sudarmi , Trinovadella Nora Isa , Bertalina Bertalina
Published: November 2022

Angka Kecukupan Energi (AKE) tahun 2017 di provinsi Lampung di bawah rata-rata nasional yaitu: 58,6 %. Untuk pertumbuhan maupun aktivitas janin selama kehamilan ibu memerlukan penambahan energi, protein dan zat-zat gizi lainnya. Konsumsi makanan tradisional (seruit) masyarakat lampung yang bahan dasarnya ikan bernilai gizi cukup tinggi, baik diberikan pada ibu hamil, untuk itu perlu kiranya tenaga bidan dan kader kesehatan diberikan edukasi tentang penyusunan gizi seimbang makanan lokal (seruit). Tujuan dari kegiatan pengabmas adalah meningkatkan pengetahuan dan sikap bidan dan kader untuk dapat mensosialisasikan gizi seimbang dengan memanfaatkan bahan makanan lokal (seruit) pada ibu hamil. Metode Kegiatan berupa penyuluhan/ pemberian materi, metode praktik demostrasi pembuatan/penyusunan menu seimbang makanan lokal (seruit) bagi bidan dan tenaga kader dilaksanakan di wilayah kerja puskesmas Marga Kencana Tulang Bawang Barat Provinsi Lampung Tahun 2020. Waktu pelaksanaan selama 6 bulan pada bulan Januari s/d Juni 2020. Hasil post-test sosialisasi tingkat pengetahuan meningkat baik 82,9% dan hasil post-test sikap bidan dan kader mendukung 80%. Hasil uji statistik didapatkan P.value= .003, Berarti terdapat perbedaan yang signifikan pengetahuan dan sikap responden setelah dilakukan sosialisasi. Rencana tindak lanjut pengabmas dengan pemantauan status gizi ibu hamil di wilayah kerja Puskesmas Marga Kencana Tulang Bawang Barat Provinsi Lampung
Promosi Kesehatan Dalam Upaya Peningkatkan Pengetahuan dan Keterampilan Mencuci Tangan, Memakai Masker, Menjaga Jarak (3M)
Authors: Triana Winda , Asmuni Asmuni , Irfan Ary , Aji Rustam
Published: November 2022

PHBS yang tidak diterapkan, salah satunya yaitu dengan tidak mencuci tangan pada air yang mengalir. Dengan kondisi sedang terjadinya wabah pandemi Covid 19 tidak menutup kemungkinan akan terjadi transmisi tersebut. Tujuan pengabmas adalah menganalisis gambaran pengetahuan sebelum dan sesudah Promosi Kesehatan. Metode pengabmas dengan melakukan survei alat ukur pre-test intervensi dan post-test, menggunakan kuesioner dan observasi. Hasil luaran, sebagian besar menjadi baik. Luaran yang dihasilkan Koran, Poster mencuci tangan, dan jurnal pengabdian masyarakat. Kesimpulan yang diperoleh dari kegiatan pengabmas ini adalah terjadi peningkatan pengetahuan dan keterampilan sebelum dan sesudah diberikan pendidikan kesehatan. Diharapkan dapat meningkatkan perilaku sehat mencegah penyakit, memelihara kesehatan, menciptakan dan memelihara lingkungan sehat, terciptanya kebijakan sekolah sehat serta berperan aktif dalam meningkatkan kebersihan perorangan dalam melakukan 3 M, mencuci tangan pakai sabun, memakai masker dan menjaga jarak dalam pencegahan Covid-19. Memanfaatkan sarana tempat cuci tangan yang telah diberikan dari kegiatan pengabmas, melanjutkan dengan menerapkan PHBS serta mengaktifkan UKS.
Pengetahuan Kader dalam Pemanfaatan Kalender 1000 Hari Pertama Kehidupan untuk Pemantauan Tumbuh Kembang Anak
Authors: Antarini Antarini , Harindra Harindra , Rosita Neng Ayu , Wulanda Ayu Febri
Published: November 2022

Pertumbuhan dan perkembangan mengalami peningkatan yang pesat pada usia dini, yaitu dari 0 sampai 5 tahun. Masa ini disebut sebagai fase “Golden Age” dengan memperhatikan tumbuh kembang anak secara cermat agar sedini mungkin dapat terdeteksi apabila terjadi kelainan dan meminimalkan disfungsi tumbuh kembang anak sehingga mencegah terjadinya disfungsi permanen. Tenaga kesehatan kader merupakan sumber daya masyarakat yang dapat membantu program kesehatan yaitu dengan meningkatkan kemampuan dalam deteksi tumbuh kembang anak. Kegiatan pengabdian masyarakat ini dilakukan dengan tujuan untuk meningkatkan pengetahuan dan penerapan ibu-ibu kader kesehatan dan ibu yang memiliki balita tentang pemantauan tumbuh kembang anak dengan menggunakan kuesioner Pra Skrining Perkembangan (KPSP) dan penggunaan kalender 1000 Hari Pertama Kehidupan (HPK). Kegiatan ini diikuti oleh 14 kader kesehatan dan 16 ibu yang memiliki balita untuk simulasi pengisian lembar pemantauan tumbuh kembang KPSP dan penggunaan kalender 1000 HPK, dilaksanakan di Desa Cengkong Abang, berlangsung selama 2 hari yaitu pada tanggal 18 dan 30 September 2020. Bentuk kegiatan ceramah, tanya jawab dan simulasi pemantauan tumbuh kembang anak dengan menggunakan lembar balik dan lembar pemantauan tumbuh kembang KPSP serta simulasi penggunaan kalender 1000 HPK. Berdasarkan kuesioner pre test yang dibagikan kepada peseta didapatkan rata-rata nilai peserta pre test yaitu 42,5. Kemudian setelah diberikan pendidikan kesehatan dan praktik simulasi tentang pengisian lembar pemantauan tumbuh kembang anak yaitu KPSP diberikan kuesioner post test dan didapatkan nilai rata-rata post test 93,5. Terjadi peningkatan pengetahuan dari peserta yaitu para kader kesehatan dan ibu yang memiliki balita, namun perlu ditingkatkan lagi penerapan dari pengisian lembar pemantauan tumbuh kembang KPSP dalam kegiatan rutin kesehatan yaitu Posyandu.
Keterampilan Konseling Pemberian Makan Bayi dan Anak (PMBA) Bagi Kader Posyandu
Authors: Meilinasari Meilinasari , Rahmawati Siti Mutia , Marbun Rosmida M , Dumaria Corazon Hanna , Suharyati Suharyati , Fitriyanti Fitriyanti
Published: November 2022

Prevalensi stunting menurut Riskesdas 2018 menunjukkan angka 30,8%. Angka tersebut masih di atas rata-rata standar yang ditentukan oleh WHO yaitu <20%. Di DKI Jakarta prevalensi stunting sebesar 27%. Data tersebut membuktikan bahwa prevalensi stunting di Jakarta masih tinggi diatas batas ketetapan WHO. Data yang diperoleh dari Puskesmas Kecamatan Kebayoran Lama Selatan menunjukkan cakupan program ASI Ekslusif sebesar 74,02% dan pemberian MP-ASI yang belum sesuai. Kegiatan Pengabdian Masyarakat yang dilakukan adalah pelatihan untuk kader posyandu yang belum pernah dilatih konseling pemberian makan bayi dan anak (PMBA). Tujuan pelatihan adalah untuk meningkatkan pengetahuan dan keterampilan kader posyandu di Kecamatan Kebayoran Lama Selatan tentang konseling PMBA. Pelatihan kader dilakukan selama 3 (tiga) hari secara daring dengan jumlah kader sebanyak 22 orang. Sebagian besar kader berumur 56-65 tahun (45,5%) dengan sebagian besar telah menjadi kader selama 1-5 tahun (54,5%). Setelah kader mengikuti pelatihan konseling PMBA terjadi peningkatan pengetahuan sebesar 11,55 poin, sikap 3,05 poin, persepsi 9,82 poin, motivasi 6 poin, tindakan 5,23 point, dan kinerja 12,87 poin. Ada perbedaan yang signifikan nilai pengetahuan, persepsi, motivasi, kinerja kader sebelum dan sesudah pelatihan. Sehingga diharapkan kader mampu memberikan konseling PMBA dengan baik kepada masyarakat.
Pelatihan Budidaya Jamur Tiram untuk meningkatkan Kemandirian dan Kesejahteraan Masyarakat di Desa Padang Ratu Kecamatan Sungkai Utara Kabupaten Lampung Utara
Authors: Hasan Amrul , Kadarusman Haris , Sutopo Agus
Published: November 2022

Jamur tiram (Pleurotus sp.) merupakan salah satu jamur konsumsi yang memiliki nilai gizi tinggi. Beberapa jenis jamur tiram yang biasa dibudidayakan oleh masyarakat Indonesia yaitu jamur tiram putih (P. ostreatus), jamur tiram merah muda P. flabellatus), jamur tiram abu-abu (P. sajor caju), dan jamur tiram abalone (P. cystidiosus). (Susilawati dan Budi Raharjo, 2010). Sebagai Sebagai bahan pangan jamur menjadi salah satu sumber protein seperti thiamine (vitamin B1), riboflavin (vitamin B2), niasin, biotin dan vitmin C serta mineral. Sebagai bahan fungsional jamur mengandung bahan aktif yang terdiri dari senyawa polisakarida (glikan), triterpen, nukleotida, monitol, alkoloid dan lain-lain yang bermanfaat untuk kesehatan tubuh. (Susilawati dan Budi Raharjo, 2010). Desa Padang Ratu Kecamatan Sungkai Utara memiliki potensi yang baik sebagai tempat budidaya jamur tiram. Oleh karena itulah, melalui Program Pengembangan Desa Mitra ini diharapkan dapat membantu masyarakat desa Padang Ratu Kecamatan Sungkai Utara, baik dari segi informasi maupun biaya, dalam mengembangkan usaha budidaya jamur tiram. Masyarakat Mitra di desa Padang Ratu berkeinginan membudidayakan jamur tiram, akan tetapi belum mengetahui teknik pembudidayaannya. Oleh karena itu, kegiatan PkM skema PPDM dosen Poltekkes Tanjung Karang membantu masyarakat desa Padang Ratu teknik Budi daya Jamur tiram. Kegiatan PkM dilaksanakan melalui beberapa tahapan yaitu, persiapan, sosialisasi, pelatihan, dan tahap terakhir adalah pendampingan dan monitoring. Materi yang disampaikan dalam sosialisasi adalah pengenalan jamur tiram, manfaat, syarat tumbuh, dan cara budidaya jamur tiram. Kegiatan pelatihan dilakukan dengan langkah sebagai berikut: Penakaran dan pencampuran media tumbuh; Pemeraman media; Pengisian media ke dalam baglog; Sterilisasi baglog; Pendinginan baglog; Inokulasi bibit jamur F3; Inkubasi dan pemindahan baglog ke dalam kumbung; Pemeliharaan; dan Pemanenan. Kegiatan pendampingan sampai dengan panen perdana dilakukan selama 13 minggu dengan rincian dua minggu pembuatan baglog, sterilisasi dan inokulai bibit ke dalam baglog, delapan minggu inkubasi baglog sampai dengan siap di buah kan, dua minggu proses pemindahan baglog ke dalam kumbung budi daya sampai siap di panen, panen perdana jamur tiram hasil budidaya mitra sebanyak 5 kg. Mitra yang membudidayakan jamur tiram sebanyak 5 orang. Kendala yang ditemui masyarakat yaitu adanya ulat dan lalat yang hinggap di baglog jamur. Solusi yang disarankan untuk mencegah dan mengendalikan adanya hama dilakukan dengan menjaga kebersihan dan sanitasi kumbung budi daya, melakukan perawatan jamur dengan teliti.
Response of Freesia (freesia Refrecta L.) Plant to Different Growth Media, Calcium Chloride And Gibberellic Acid
Authors: Mosa Hajar Faesal , Abdulrahman Yousif Ali
Published: November 2022

A pot experiment has been conducted in a plastic house at the Department of Protected Cultivation, Technical Institute of Zakho, Duhok Polytechnic University during the fall season of 2021–2022 to investigate the effects of three growth media (peat moss, loam + peat moss (1:1) and clay + peat moss (1:1)), foliar spraying of calcium chloride (CaCl2) at three concentrations (0, 500 and 1000 mg. L-1) and Gibberellic acid (GA3) at three concentrations (0, 200 and 400 mg. L-1) on vegetative growth, flowering and corm yield of freesia (Freesia refrecta L.) plant. The experiment was laid out in a Randomized Complete Block Design (RCBD) of three factors with three replicates. The obtained results displayed that the peat moss medium surpassed other media in giving the highest vegetative growth traits (plant height, leaf area, and number of leaves per plant) as well as enhancing flowering traits (number of florets/spike, and vase life of cut flower) and corm yield traits (number of produced corm/plant, and corm volume). The same significant impact was exhibited by CaCl2 at concentrations of 500 and 1000 mg. L-1. Whereas GA3 at concentrations of 200 and 400 mg. L-1 improved most studied traits except number of florets per plant and vase life of cut flowers. The maximum vegetative, flowering, and corm harvest traits were obtained from grown plants in peat moss medium and by spraying them with increased concentrations of CaCl2 and GA3. Therefore, the peat moss medium in combination with increased concentrations of GA3 and CaCl2 is recommended for the improvement of freesia production quality and vase life
Homocysteine Level Status in Patients with Rheumatoid Arthritis in Duhok: in Relation to Disease. Activity Score
Authors: Younis Sherzad Saeed , Issa Najlaa Kadhm , Sulaiman Dhia Mustafa
Published: November 2022

Rheumatoid arthritis (RA) causes high rate of the mortality. Cardiovascular disease (CVD) is markedly elevated in RA partly due to accelerated atherosclerosis (AS) from chronic inflammation. Homocysteine’ elevation (Hcys) strongly related to the AS and CVD’s progression in RA. Current study aims to evaluates Hcys level status and its relation with disease activity (DA) and inflammation marker (CRP) in Duhok RA patients. Sixty-four RA patients (case) were involved in this study with equal number of healthy individuals (control), means± SD of their age were 47.78 ± 14.08 and 46.98 ± 15 respectively. ratio of females to males was (8.1 and 7.0) in case and control respectively. Blood was analyzed and RA related laboratory and biochemical markers were investigated. The results revealed that Means±SD of Hcys was higher in case comparing to control (17.30±8.52 and 7.2±3.4) respectively. RA patient with high DA score recorded higher percentage intra group of increased Hcys level (52%). This study concludes that there is a strong association between Hcys level and RA activity, severity and inflammation process in RA Duhok patients. Hcys could play role as a predictor marker helping physicians for good monitoring and managing RA disease
Market Reaction to the Introduction of K-IFRS 1116
Authors: Choi Jong-Seo , Kim Jeong-Mo
Published: November 2022

This study examines the Korean stock market reaction to the introduction of K-IFRS 1116 (IFRS 16 equivalent) which effectively eliminates the operating lease and requires all lease contracts to be considered as finance leases. An event study is conducted whereby abnormal returns around the standard announcement are examined in conjunction with selected firm characteristics. We find that the level of operating lease usage and extent of financial constraint are negatively associated with the market reaction following the announcement of the K-IFRS 1116. However, an interaction effect between the two variables is found to be absent. Additionally, we find that this negative market reaction to financial constraint is mostly led by severely financially unhealthy firms that disregard operating lease usage. We interpret the results of operating lease usage and financial constraint to demonstrate the effects of the deprival of off-balance-sheet benefits and an expectation adjustment in investors' perceived future cash flow prospects, respectively. These findings are consistent with the impact of capitalizing leases on financial ratios and risk assessment of affected companies. We contribute to the literature and practice by providing evidence on the market participants' perception of the implementation of revised lease accounting standards.
Socio-political passport of Zakarpattia (Ukraine): a brief history of the region’s survival in Central Europe
Authors: Tokar Marian
Published: November 2022

Zakarpattia is perhaps the only region of contemporary Ukraine which during the twentieth century has experienced complex political processes of regionalization and adaptation to different states and their political systems. A characteristic feature of the changes in the region was a frequent transition of political conditions from authoritarian to democratic styles of state governing of the title nations which had implanted in Zakarpattia their political rules trying to change the political culture and political consciousness of local elites and citizens.
Applied governments’ strategies for brain drain prevention
Authors: Nacházelová Eliška
Published: November 2022

Currently, many countries are facing the issue of outmigration of highly skilled workers. Based on different strategies and policies, this paper proposes a regulatory framework for brain drain. In this article, we focus on the formats and support instruments through strategies and government policies, followed by their critical assessment. The methodology, based on the review of relevant literature, aims to reflect the academic discourse regarding the issue of brain drain and, particularly, the goal of return migration. Diverse strategies are presented, ranging from financial approach to technology parks, innovation hubs, and talent markets. Moreover, the problems caused by migration, such as brain waste, are investigated. The investigation is based predominantly on European strategies. Future research could precisely focus on the application of strategies adopted and tested by a different country where positive results have already been detected. This work could serve as a stepping stone for the investigation of this phenomenon, the subsequent analysis of strategies and future impact.
On Digital Models: Responding to Viral Metaphors in Pandemic Times
Authors: McKinney Cait , Cifor Marika
Published: November 2022

COVID-19 has been a crisis represented and interpreted through models. Models are metaphors that illustrate one phenomenon in and through another that is better understood or seemingly more transparent. In this article, we consider digitally driven COVID-19 models that draw on the certainty of data from smartphones and social networks to make predictions about a poorly understood virus. Network data normally used to model information spread drive models of an actually existing biological virus. A return to HIV network models of the 1980s helps map the social implications of this latest turn to modeling. These earlier models were used to hone stigmatizing viral metaphors about behavior, risk, and exposure, in the shadow of an emerging digital culture. Thinking across COVID-19 and HIV modeling demonstrates how models can support personal responsibilization, be used to blame “bad” actors, and justify the creep of new surveillance practices under the rubric of “Data for Good” programs. Drawing on critical HIV and queer studies, we argue that the people and behaviors that are opaque to viral models and their methods of capture present potential avenues for speaking back to digital virality’s terms. We highlight these exceptions, which show how certain lives make trouble for models and their sensibilities, telling of queer forms of life, desire, and contact that evade modeling altogether.
Daphnia and Apollo: An Epigenetic Fable
Authors: Kenney Martha
Published: November 2022

Environmental epigenetics is a field of molecular biology that studies how signals from the environment (e.g., food, toxicants, and even our social milieu) affect gene expression. Although, for some, environmental epigenetics promises a new and dynamic account of the relationship between organisms and their environments, current research using model organisms often relies on stereotypical assumptions about gender, race, class, and sexuality in humans (Kenney and Müller 2017). In this article, rather than simply critiquing dominant narratives, I tell a different story—a feminist fable about small crustaceans called Daphnia, who display remarkable epigenetic responses to their environments. For example, many species of Daphnia are made up of clonal females who reproduce asexually, but when resources are scarce they produce males and practice sexual reproduction. In the presence of predators, they grow helmets and neckteeth, passing these adaptations along to their clonal daughters—a potentially epigenetic inheritance. Working within the metaphoric tissue of technoscience, I bring recent research on Daphnia epigenetics together with the story of Daphne and Apollo from Ovid’s Metamorphoses in order to activate new possibilities for understanding the relations between humans and animals, organisms and their environments.
Natural Metaphors for Network Gathering: Technologies of Meeting at the Allied Media Conference
Authors: Paredes Veronica
Published: November 2022

In this article, I explore how nature metaphors are used within communities related to the Allied Media Conference (AMC) in Detroit. The AMC celebrated its twentieth anniversary in 2018, and took place annually in Detroit for twelve years leading up to that milestone (Allied Media Projects 2022b). Beyond AMC’s commitment to Detroit, the conference offers a compelling set of case studies for considering dialogue between intentional praxis of gathering and important issues related to environmental racism, popular education, and science fiction. AMC is designed to explore methods of building and sustaining within media-based organizing, while the conference itself models practices of building and sustaining within its own network. Primarily focused on adrienne maree brown’s book Emergent Strategy (2017) and the mobile multimodal art installation Beware of the Dandelions (2015–2016) from the collective Complex Movements, this paper argues that AMC uniquely weaves components together that create the conditions for studying organizational process through understandings of the natural world.
For Careful Slugs: Caring for Unknowing in CS (Computer Science)
Authors: Britton Loren , Pritchard Helen
Published: November 2022

Careful Slugs are metaphors that speculatively care for diverse practices within and alongside Computer Science. In this image-text paper we wonder with CS (Careful Slugs)––the materiality and metaphor that they generate as they encounter computational infrastructures, digital design, and interfaces. Through queer playfulness and promiscuous metaphorical practice, we propose CS as an opening metaphor for CS (Computer Science) departments where the hardened muscular lines of models and predatory based solutionisms beckon some defensive slime. As those that traverse ever-shifting and undone grounds, CS (Careful Slug) emerges from a critical disability studies perspective. We outline to practice, CS (Careful Slug) is to practice a slow “soft gooey”; to shield using protective mucous layers; to make chemical binds sticky enough to hold in-place inconclusively yet with possibilities of lubricating accountability. We invite you to sink with us into soft gooey worldings of slug-imaginings not to overburden the slug but to speculate how metaphors, might contribute to trans*feminist technoscience, accessibility, and CS (Computer Science) concerns.
GENDER DIFFERENCES IN LEVELS OF STEROID HORMONES IN HEART CELL MITOCHONDRIA AT THE STAGES OF B16/F10 MELANOMA DEVELOPMENT COMBINED WITH CHRONIC NEUROGENIC PAIN
Authors: Frantsiyants E. , Neskubina I. , Kaplieva I. , Surikova E. , Cheryarina N. , Bandovkina V. , Pogorelova Yu. , Shikhlyarova A. , Trepitaki L. , Nemashkalova L. , Pozdnyakova V. , Soldatkina N. , Maslov A.
Published: November 2022

Aim - an analysis of levels of steroid hormones in heart cell mitochondria at the stages of B16/F10 melanoma development in combination with chronic neurogenic pain in male and female C57BL/6 mice. The study included male and female C57BL/6 mice (n=336). Experimental groups were: intact animals (♂ n=21; ♀ n=21); controls (♂ n=21; ♀ n=21) with a model of chronic neurogenic pain (CNP); the comparison group (♂ n=63; ♀ n=63) with melanomas (B16/ F10); the main group (♂ n=63; ♀ n=63) (CNP+B16/F10) with melanoma transplanted 3 weeks after the CNP model creation. Levels of estradiol (pg/g protein), estrone (pg/g protein), progesterone (ng/g protein), total testosterone (ng/g protein), and free testosterone (pg/g protein) were determined by ELISA in mitochondrial samples. In animals with CNP, changes in levels of steroid hormones were detected only in heart mitochondria of female mice: estradiol was reduced by 4.6 times, estrone by 2.2 times, progesterone by 1.8 times (p˂0.05), and total testosterone by 2.4 times compared with intact values. Melanoma growth (3 weeks) in females downregulated levels of estradiol by 1.7 times (p˂0.05), estrone by 1.8 times (p˂0.05), progesterone by 2.1 times, and total testosterone by 2.3 times compared with intact values. In males, only total testosterone decreased by 2.1 times during the same period. Melanoma growth in presence of CNP (3 weeks) in females decreased levels of estradiol by 1.6 times (p˂0.05) compared with control val- ues, while males showed reduced levels of estradiol and total and free testosterone by 1.3 times (p˂0.05), 1.9 times (p˂0.05) and 2.7 times, respectively, as well as elevated levels of estrone by 1.6 times (p˂0.05). CNP and the growth of B16/F10 melanoma to a greater extent weaken the heart of females due to the involvement of a wider spectrum of hormones and a decrease in their levels in the heart mitochondria, compared to males. When CNP was combined with B16/F10 melanoma, a more significant hormonal imbalance was determined in males than in females.
POTENTIAL MARKERS OF RECURRENCY OF UROLITHIASIS DISEASE AND THE ROLE OF STONE FORMATION INHIBITORS IN RECURRENT CALCIUM OXALATE NEPHROLITHIASIS
Authors: Budanov A. , Medvedev V. , Kurzanov A. , Bykov I. , Basov A. , Rusinova T.
Published: November 2022

Nowadays urolithiasis (nephrolithiasis) is a common disease, which treatment is a serious task of health care ser- vices not only in Russia, but throughout the world. At the same time, stones of a calcium-oxalate nature are the most common stones in patients with this pathology – in about 70-80% of cases. It is also worth noting that this disease not only has rather painful manifestations, and its treatment requires large financial costs, but also has a complex multi- factorial multistage pathogenesis, understanding the mechanisms of which can provide a key to the development of the most successful therapy. Pathogenesis itself consists of several stages, such as nucleation with the formation of a crystallization center, crystal growth, aggregation and their attachment to the surface of epithelial cells.

It is known that the human body contains various substances that affect the processes of stone formation. Thus, stone formation promoters facilitate their crystallization, and inhibitors prevent it. There is a delicate balance between promoters and inhibitors, and their imbalance is often a decisive factor in pathogenesis. By their chemical nature, inhibitors can be both inorganic and organic (proteins, glycosaminoglycans) substances. The latter are especially attracting attention, since at various concentrations they can act as both inhibitors and promoters of stone formation. To fully understand the mechanisms of calcium oxalate stone formation, this review analyzes current data on inhibitors of recurrent nephrolithiasis and their role in the pathophysiology of the process of renal stone formation.
ELECTRON MICROSCOPY OF THE DISPERSED PHASE OF DISTILLED WATER
Authors: Yakhno T. , Bogdanov C. , Sanin A. , Yakhno V.
Published: November 2022

This article continues a series of works by the authors on the study of the dispersed phase of water using an optical microscope. Previously, it was found that each unit of the dispersed phase is a NaCl microcrystal surrounded by a thick layer of water of hydration, which prevents its dissolution. When free water evaporates from the glass surface, the osmotic pressure in the remaining water increases, which leads to the dissociation of hydration shells and contact of the salt with water. After complete evaporation, large NaCl crystals and gel-like non-evaporating water remain on the glass substrate. The use of a scanning electron microscope made it possible to reveal a number of previously unknown details: the formation of small crystals of sodium chloride on the surface of the dispersed phase of water and the growth of crystals on filaments of gel-like water. According to the authors, a significant part of NaCl in high-resistivity water is in the form of crystals inside the dispersed phase, which manifests itself after the evaporation of free water. The versions of other authors who observed "stable water clusters" in serially diluted solutions are discussed.
AZULENES OF LEAF SURFACE AS A PROTECTIVE OPTICAL FILTER
Authors: Roshchina V. , Prizova N. , Khaibulaeva L.
Published: November 2022

Reactions to ozone of surface cells of leaves with blue or silver color in plant species: meadow-rue Thalictrum minus L., oleaster Elaeagnus L., white willow Salix alba L., buckthorn Hippophae rhamnoides L., creeping clover Trifolium repens L, red clover Trifolium pretense L., ryegrass pasture Lolium perenne Engels were studied. They had no noticeable spectral changes. It has shown that the surface layers of the cuticle and the cell wall of these plants contained azulenes. In the leaf absorption spectra, the maxima characteristic of these blue pigments of 580-585 nm and 608-610 nm, respectively, were noted, and in the fluorescence spectra – 410 or 430 nm. It has assumed that these pigments may be the primary targets for ozone in species with blue or silvery leaf color, and their antioxidant properties determine low sensitivity to ozone. In this case, the blue pigments serve as a protective optical filter against ultraviolet radiation and ozone formed with its participation.
PECULIARITIES OF SALICYLIC ACID AND ASPIRIN BINDING TO ACID-SENSITIVE ION CHANNELS OF TRICHOPLAX ADHAERENS
Authors: Kuznetsov A. , Kurchenko V. , Voronin D. , Zavyalova O.
Published: November 2022

Acid-sensitive ion channels (ASICs) represent a family of membrane three subunits' DEG/ENaC proteins that transport Na+ ions and are found in representatives of many taxonomic groups [1]. DEG/EnaC channels include such structural domains as the palm, β-ball, knuckle, finger, thumb and wrist [2]. They are involved in many physiological processes as proton-regulated channels, when the pH of the extracellular environment changes [3]. DEG/ENaC channels are associated with a wide range of cellular functions, such as pain sensation and epithelial Na+ transport [4]. These channels have different gating properties, from almost constant opening to rapid inactivation, so numerous pathologies are associated with damage to these channels [5]. Traditionally, the functions of these channels have been studied using toxins [6]. We found 9 acid-sensitive ion channel genes and 12 homologs with unknown function in the Trichoplax adhaerens genome, of which two amino acid sequences (QEP99390.1 and XP_002115321.1) were folded into 3D-models and used to dock amiloride, aspirin and salicylic acid. Salicylates have multiple binding sites on the acid-sensitive trichoplax receptors, including the acid pocket that is a proton sensor, which suggests their possible application in modulating the activity of the ASIC-channels of T. adhaerens.
SPATIAL STRUCTURE OF ALFA-LAKTORFINE MOLECULE
Authors: Akhmedov N. , Agayeva L. , Abbasli R. , Ismailova L.
Published: November 2022

Opioid peptides are currently considered the most studied group of peptide signaling substances. Opium causes pain relief, sedation and falling asleep, as well as a euphoric state and a number of vegetative reactions. Opioid peptides are of animal and plant origin. A number of exogenous peptides obtained from food have opioid-like properties. Such peptides were called exorphins, there are dozens of representatives. The alpha-laktorphine molecule is a representative of this class. The conformational possibilities of the Tyr-Gly-Leu-Phe alpha-lactorphine molecule were studied by the method of theoretical conformational analysis. The potential function of the system is chosen as the sum of non-valence, electrostatic and torsion interactions and the energy of hydrogen bonds. The low-energy conformations of the alpha-laktorphine molecule, the values of the dihedral angles of the main and side chains of the amino acid residues that make up the molecule were found, and the energy of intra- and interresidual interactions was estimated. It was shown that the spatial structure of the alpha-laktorphine molecule can be represented by eleven forms of the main chain. The results obtained can be used to elucidate the structural and structural-functional organization of exorphin molecules.
MEASUREMENT AND CALCULATION OF ELASTIC CHARACTERISTICS OF THE WALL OF THE HUMAN COMMON BILE DUCT
Authors: Muslov S. , Zaitseva N. , Korneev A. , Sinitsyn A.
Published: November 2022

In the work, stress-strain curves in the longitudinal and annular directions were experimentally obtained and the differential elastic modules of the wall of the segment of the human common bile duct on cadaver material were determined. Knowledge of the physico-mechanical properties of the bile ducts can be used to understand the functioning of the entire human biliary system, to clarify aspects of its aging due to qualitative structural and functional changes in tissues, to diagnose diseases and for therapeutic purposes. One of the early manifestations of changes in the properties of the ductal wall caused by the development of a pathological process in it is a violation of its elasticity, which is reflected in an increase in stiffness indicators. It is established in the longitudinal direction of choledochus: kPa and kPa (regression confidence coefficient 0.99), in the annular direction – kPa and kPa (regression confidence coefficient 0.98), respectively.
ELASTIC PROPERTIES OF CRYSTALS OF BIOCOMPATIBLE TINI-BASED ALLOYS WITH SHAPE MEMORY
Authors: Muslov S. , Sukhochev P.
Published: November 2022

The authors present their own and literature data on the characteristics of elastic properties of crystals of biocompatible alloys based on titanium nickelide (nitinol) TiNi with shape memory, which have been widely used in science, technology and medicine. Elastic constants cij, malleability coefficients sij, Poisson coefficients μmin, μmax, <µ> and elastic anisotropy A, obtained experimentally and computationally, were evaluated.The numerical values of the studied parameters are analyzed in detail from the point of view of descriptive statistics. To visualize the differences in elastic characteristics, “box and whiskers” diagrams and a diagram with areas are used. Knowledge of the elastic constants of the TiNi crystal lattice and alloys based on it made it possible to calculate the values of macroscopic elastic modules E and G, the Poisson's ratio μ and their orientation dependence. Based on the data analysis, it is concluded that the low level of elastic properties of TiNi (nitinol) based alloys can be used, for example, in the development of bionic prostheses for medicine.
PHOTOCHROMIC LIGANDS FOR MODIFICATION OF METAL CATIONS AND QUANTUM DOTS
Authors: Belikov N. , Demina O. , Levina I. , Lukin A. , Safinova A. , Petrovskaya L. , Varfolomeev Sergey , Khodonov A.
Published: November 2022

In this paper, we consider the studies carried out by the authors aimed at developing new hybrid structures and methods for obtaining a family of photochromic labels capable of photocontrolled interaction with inorganic components, as well as the results of studying their photochromic behavior and the selectivity of complex formation processes. In this paper, special attention is devoted to the choice of the desired composition and structure of label molecules and the practical implementation of laboratory technology for the synthesis of a set of target compounds with specified optical parameters. The data obtained open up prospects for the use of a new generation of photochromes based on functionalized spiropyrans as new hybrid materials for the creation on their basis: metal detectors, components of photochromic systems, and prototypes of molecular electronics smart devices.
THE INFLUENCE OF SOCIAL STRATEGY AND PUBLIC POLICY OF STATE DEFENCE AWARENESS MANAGEMENT ON ORGANIZATIONAL PERFORMANCE OF THE MINISTRY OF DEFENSE MEDIATED BY STRATEGIC CHANGE MANAGEMENT
Authors: Purwaningsih Endang , Jasfar Farida , Kusnadi
Published: November 2022

State Defence awarenessis is the collective awareness of the Indonesian nation that is needed by the state to defend its sovereignty, territorial integrity, and national safety in the face of every threat. The aim of the research is to analyze influence variable social strategy and public policy in the State Defence Awareness Management of organization performance of the Ministry of Defense mediated by strategic change management. This study uses quantitative approach with study expanatory. Data analysis using Structural Equation Model (SEM) with using Smart PLS 3.0 for analyze connection or influence variable dependent with variable independent. Research results show that by general there is influence direct social strategy and public policy on organizational performance, as well as there is influence direct strategic change management towards organizational performance as well as there is influence non direct social strategy and public policy to organizational performance mediated by strategic change management. Implication theoretical from this study is strategic change management as mediating social strategic and public policy able for increase organizational performance Ministry of Defense in implementation coaching State Defence Awareness Management. While implication strategic from this study is the strategy, policy, and management changes in the State Defence Awareness Management is very influential to performance Ministry of Defense organization, so that need enhancement every dimension to increase trust public as well as faithfulness every source power involved in implementation coaching State Defence Awareness Management.
Our Lives as Women: An Analytical Framework of What Makes Q'eqchi' Women Sick
Authors: Natalya Jones
Published: November 2022

The global pattern of women suffering from worse health than men, based on cultural, economic, and biological factors, was found in a small group of Q’eqchi’ women in the Toledo district of Belize. This research follows the health narratives of 20 Q’eqchi’ women to determine what they believe causes their poor health. Through in-depth personal interviews Q’eqchi’ women shared that they suffer from backaches, headaches, pain in their bones, and heavy bleeding. Further, the women also reported ‘thinking too much’ as a factor in their health caused by their reproductive roles. Through thematic analysis and an extensive review of varied literature, this research found that the colonization-rooted Latin gender roles of machismo and marianismo work to sustain Q’eqchi’ women to the domestic sphere. Based on the fact that most Q’eqchi’ women are mothers and wives, these women are stripped of opportunities to obtain education and gain employment, leading to high stress levels and a dependency on their partners for socioeconomic support. Moreover, Q’eqchi’ women’s domestic responsibilities involved arduous physical labour with little rest or help from their male spouses. This labour, combined with the pressures and responsibilities associated with their sex, results in their somatic and psychosomatic expressions of sickness. The research presented in this paper underpins the significance of women’s sex and cultural systems when analyzing global health outcomes. More nuanced considerations of cultural structures, like those mentioned by Q’eqchi’ women, need to be prioritized by policymakers and global health initiatives internationally to better support women’s health.
A Pathway to Reconciliation within ‘North American’ Archaeology
Authors: Sielsky Kali
Published: November 2022

As we begin to enter an era of reconciliation in archaeology, we must look at the foundation upon which the discipline has been built and start to dismantle the colonial ideologies which have been embedded within. A number of new practices and approaches have emerged over the past decade, through community and public based archaeology, placing the community at the forefront of the research. These newer approaches have set out to challenge the ways in which the discipline had been conducted previously, creating pathways forward for reconciliation. The following commentary is based on my experience as a student researcher and professional archaeologist over the past six years ─ experience which has been shaped by my identity and the lens it informs and which offers only one perspective towards the important and emerging narrative on reconciliation within archaeology.
Peran FBXW7 pada Stem Cell Normal dan Cancer Stem Cell
Authors: Hidayat Moulid , Hidayat Moulid , Fariz Nurwidya
Published: November 2022

F-box and WD40 repeat domain-containing 7 (FBXW7) adalah protein F-box yang merupakan komponen sistem ubiquitin proteasome yang berhubungan dengan beberapa protein onkogenik penting seperti Notch, c-Myc, cyclin E and c-Jun dalam mengatur proses pertumbuhan dan perkembangan sel, metabolism sel, diferensiasi dan apoptosis. Beberapa studi terkini menunjukkan bahwa FBXW7 berperan dalam perkembangan beberapa stem cell, mencakup proses self-renewal, multipotensi, diferensiasi, dan survival. Cancer stem cell (CSC) diketahui merupakan salah satu penyebab resistensi tumor terhadap berbagai kemoterapi, kekambuhan dan metastasis tumor. FBXW7 berperan terhadap kondisi quiescence pada CSC dengan mengatur substrat downstream c-Myc. Kondisi quiescence pada CSC dapat diinhibisi dengan memblokade peran FBXW7 melalui pathway upstream and downstream FBXW7 sehingga diharapkan dapat mengatasi resistensi dan kekambuhan tumor. Artikel telaah pustaka ini akan memaparkan peran FBXW7 pada stem cell normal dan pada cancer stem cell hubungannya dengan pengembangan terapi.
Hipersensitivitas Terhadap Vaksin
Authors: Asmara I Gede Yasa
Published: November 2022

Vaksin mirip dengan obat yaitu dapat berpotensi menimbulkan reaksi hipersensitivitas baik ringan maupun berat. Proses pembuatan vaksin harus memperhatikan keseimbangan antara aspek imunogenisitas dan reaktigenisitas. Hampir semua komponen vaksin berpotensi menimbulkan reaksi hipersensitivitas namun mekanisme alergi hanya sebagian kecil dari seluruh efek samping vaksin. Reaksi hipersensitivitas terhadap vaksin ada dua jenis yaitu reaksi segera maupun reaksi lambat. Penegakan diagnosis reaksi hipersensitivitas terhadap vaksin mengutamakan anamnesis dan pemeriksaan fisik. Pemeriksaan tes alergi belum terstandar dan tervalidasi. Penanganan reaksi hipersensitivitas terhadap vaksin hampir sama dengan penanganan reaksi alergi secara umum. Keputusan pemberian re-vaksinasi sangat individual tergantung kondisi masing-masing pasien.