bluuebunny/crossref_metadata_2025 huggingface dataset:
TO EVALUATE CLINICAL AND PARACLINICAL CHARACTERISTICS OF STROKE AND RELATIONSHIP TO THE HYPERTENSION GRADES
Authors: Nguyen Thanh Tin , Nguyen Ke Tai , Le Chuyen
Published: May 2021

Introduction: Stroke is the leading cause of death and disability in the world. Diagnostic imaging is useful for early diagnosis, assessing severity and localization, results in the better outcome and limiting disability. Hypertension is the most important factor cause stroke but variable. Effective controlling of blood pressure helps prevent stroke.

Objectives: To study both clinical and paraclinical characteristics in stroke patients having hypertension; Relationship between these characteristics and hypertension grades.

Methods: Cross- sectional study. 115 stroke patients having hypertension were treated in the Department of Cardiology, Hue University Hospital, from September 2017 to April 2018.

Results: Most patients were ≥ 50 years old; male/female ratio=1.21. Most patients were hospitalized at > 6 hours after onset; and had more than 1 risk factor, mainly dyslipidemia; ischemic stroke was prevailed (83.5%); the most common symptoms: hemiplegia, dysarthria; the Glassgow Coma Score (GCS) at mild and the NIHSS score at average scale were dominant; mainly unilateral hemispheric injuries. 1-site infarction was major, commonly in the midbrain arteries; intracranial hemorrhage intracerebral hemorrhage was dominant at central gray nuclei, capsual interna, hippocampus. The glucose and lipid indices did not show any statistically significant difference between ischemic and hemorrhagic strokes. Hospitalized blood pressure of hemorrhagic stroke was (166.58 ± 27.29/95.79 ± 15.39) higher than that of ischemic group (154.11 ± 23.64/87.08 ± 12.97) (p < 0.05). Incidence of hemorrhagic stroke, GSC and NIHSS scores of Grade 2 hypertension up were respectively 17.7%, 8.1% và 61.3%; while in Grade 1 hypertension were respectively 15.1%, 3.8% and 56.6% (p > 0.05).

Conclusions: Mean value of hospitalized blood pressure in hemorrhagic stroke was significantly higher than that in ischemic (p < 0.05). Unilateral hemisphere damages were predominant; middle cerebral infarction is most common in ischemic while intracerebral hemorrhage at central gray nuclei, capsule interna and hippocampus is dominant in hemorrhagic stroke. Grade 1 hypertension was lower the incidence of hemorrhagic stroke as well as better in both GSC and NIHSS scores than Grade 2 hypertension up (p > 0.05).

Key words: ischemic stroke, hemorrhagic stroke, hypertension grades, Glassgow, NIHSS
ERRORS IN ENTERING ICD-10 CODES AT GENERAL HOSPITAL OF QUANG NGAI PROVINCE
Authors: Nguyen Hoang Lan , Le Van Tri
Published: May 2021

Aim: To identify common errors in entering ICD-10 codes at General Hospital of Quang Ngai province and assess knowledge in assignment of ICD-10 code of health staff and factors affecting it at the hospital.

Materials and Method: A cross- sectional study was conducted to review randomly 800 medical records of 8 main departments of the hospital based on criteria of Ministry of Health and interview randomly 400 health staff who were responsible for entering ICD- 10 codes by a self-reported questionnaire.

Results: The rate of medical records that achieved criteria of entering ICD-10 codes was 64.5%, the other was medical records facing errors (35.5%). 57.5% of health staff achieved good knowledge in entering ICD-10 codes. Factors affecting entering ICD-10 code were found to be high professional level, participating in training courses and updating information frequently, access to guideline documents and regulations concerning rewards.

Key words: ICD-10, medical record, entering ICD-10 code, hospital
ASSESMENT OF DENTAL ENAMEL DISCOLORATION BY FOOD: AN IN VITRO STUDY
Authors: Nguyen Thi Thuy Duong , Bui Huy Chuong , Nguyen Thanh Tung
Published: May 2021

Background: Extrinsic tooth discoloration is a common problem with great influence on tooth color and smile esthetics. Consumption of colored beverages increases the risk of these extrinsic stains formation. The aim of the present study was to assess the effect of colored beverages on tooth discoloration.

Materials and Methods: 80 bovine specimens were prepared from 80 extracted bovine central incisors and randomly divided into four groups (n = 20/group): immersed in tea, coffee, cola and artificial saliva (control). The immersed time was 10 min per day in 1 and 2 weeks. Color changes were evaluated by L*, a*, b* and ∆E* values of CIELAB system using Crystaleye spectrocolorimeter.

Results: Tea caused the L* values decreasingafter 1 day immersion (p < 0.05), while the a* values increased and the b* values had no changes after 2 week immersion. Coffee caused the L* and a* values decreasing after 1 day immersion (p < 0.05) while the b* values had no changes. Cola caused the L* value decreasing after 1 day immersion (p < 0.05) while a* and b* values had no changes. Following 3 weeks immersions, the color change values (∆E*) of both 3 groups were higher than 3.7 and increased over time.

Conclusions: Tea, coffee and cola cause staining on bovine specimens in different levels, the primarily changes are on lightness decreasing (L*), the saturation (a* and b*) changes depend on the type of beverages. In all evaluated time points, the highest ∆E* values were observed with tea, coffee showed lower ∆E* values and cola showed the lowest ∆E* values.

Key words: tea, cofee, cola, spectrocolorimeter, extrinsic discoloration
THE RELATIONSHIP BETWEEN SERUM FGF-23 CONCENTRATION AND CLINICAL AND SUBCLINICAL FACTORS IN PATIENTS WITH CHRONIC KIDNEY DISEASE
Authors: Nguyen Huu Vu Quang , Vo Tam
Published: May 2021

Objective: To evaluate the relationship between serum FGF-23 levels and other factors affecting bone mineral disorders in chronic kidney disease.

Method: Cross-sectional study, describe and analyze of the relationship between FGF-23 and biochemical parameters, clinical characteristics of 149 patients with chronic kidney disease.

Results: For conservative group, FGF-23 level correlated positively with level of urea, creatinine and inversely correlated with glomerular filtration rate (GFR); the level of urea, creatinine and GFR are the three most influential factors on FGF-23 level, the changes in level of urea, creatinine and GFR explain 30.6% and 29.5% and 11.2% respectively of change in FGF-23 level with p < 0.05. For hemodialysisgroup, there is a positive correlation between the level of FGF-23 and the level of total calcium, Phosphorus and calcium-phosphorus accumulation; Total calcium, Ca x P level are the twoo most influential factors on the level of FGF-23, total calcium changes, Ca x P explain 29.7% and 18.8% respectively of change in FGF-23 level with p < 0.05.

Conclusion: There is a strong correlation between FGF-23 levels and factors affecting bone mineral disorders in patients with chronic kidney disease.

Key words: chronic kidney disease, fibroblast growth factor 23
COMPLIANCE TO ANTIHYPERTENSIVE MEDICATIONS IN OUTPATIENT TREATMENT PRIOR TO BE AD- MITTED TO DEPARTMENT OF INTERNAL MEDICINE, HUE UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL
Authors: Le Chuyen , Nguyen Thanh Tin , Do Thi Hong Diep , Nguyen Thi To
Published: May 2021

Introduction: Hypertension is a global problem with large prevalence and rapidly increasing. Hypertension is a chronic disease that causes damage to targeted organs, results in morbidity or mortality affecting the patient and the burden of public health. Effective blood pressure management helps reduce the risk of complications and reduce morbidity, bringing quality of life to patients. This demanding requires long-term, continuous treatment and combined solutions, in which compliance with drug therapy plays a very important role. Objectives: To investigate the current status of compliance with hypertension medication and the relationship between compliance to drug therapy and related factors.

Methods: Cross-sectional study. The subjects included 224 hypertensive patients with a history of outpatient management who were being received treatment at the Department of Internal Medicine, Hue University of Medicine and Pharmacy Hospital.

Results: The compliance rate for the use hypertension medication was 72.3%, corresponding to a good level of 39.1% and an average of 33.2%. The rate of poor compliance and non-compliance was 27.7%.

Conclusions: Many factors, including demographic characteristics (gender, age, geography, job, education), disease-related traits (circumstance of diagnosis, duration of disease), patient knowledge of hypertension (BP, medication, diet, activities, periodic examination) and the provision of medical information (risks, treatments, reminder, health insurance), were found to be significantly associated with compliance to drug therapy.

Key words: Compliance to drug therapy, hypertension, Morisky mediation adherence scale-8 (MMAS-8)
THE COMORBID CARDIAC DISEASES AND RELEVANT COMPLICATIONS OF NON CARDIAC SURGERY IN THE ELDERLY, HUE UNIVERSITY OF MEDICINE & PHARMACY HOSPITAL
Authors: Tran Thi Thu Lanh , Nguyen Van Minh , Tran Xuan Thinh
Published: May 2021

Background: The comorbid cardiac diseases are a cause of increased risk for perioperative complications and increased perioperative mortality, especially in elderly patients.

Objectives: To evaluate the incidence of comorbid cardiac diseases and relevant complications of noncardiac surgery in the elderly patients at Hue University of Medicine and Pharmacy Hospital.

Materials and method: In a prospective descriptive study, 400 patients (≥ 60 years old) have been operated from 8/2018 to 2/2019 at Hue University of Medicine and Pharmacy Hospital.

Results: Hypertention (63.0%), valvular diseases (6.3%), arrythmias (4.3%), ischemic cardiomyopathy (3.3%), cardiomyopathy disease (3.8%), patients with coronary stent (1.3%), patients with permanent pacemaker (1.0%). Induction: Hypotension (70.5%). Emergence: hypertension (54.8%), tarchycardia (40.5%), acute pulmonary edema (0.5%). Hypotension in neuraxial anesthesia (26.5%).

Conclusion: The older patients often have the comorbid cardiac diseases. The most common is hypertension. Hypotension is the most common complication in induction, and hypertension and tarchycardia is the common complications in emergence.

Key words: comorbid cardiac diseases, elderly, surgery
A STUDY OF CLINICAL, SUBCLINICAL FEATURES AND THERAPEUTIC EFFICACY OF SECUKINUMAB IN PATIENTS WITH ACTIVE ANKYLOSING SPONDYLITIS
Authors: Nguyen Mai Ha Linh , Nguyen Hoang Thanh Van
Published: May 2021

Objectives: To study clinical, subclinical features and to evaluate therapeutic efficacy of Secukinumab in patients with active Ankylosing Spondylitis (AS).

Patients and methods: Descriptive, comparative, retrospective and prospective study, combination with treatment intervention in patients diagnosis with AS, following to modified ACR-1984 criteria (New York criteria) who are inpatient or outpatient in the Department of General Internal Medicine - Endocrinology of Hue University of Medicine and Pharmacy and in the Department of Nephrology and Rheumatology of Hue Central Hospital from May 2018 to August 2019.

Results: The study recruited of 38 patients, (76.3% males) with mean age of 29.76 ± 9.75 years old. The age of onset was about 23 years old and the percentage of patients who were diagnosed AS under 30 years old was 73.7%. The majority of patients were hospitalized with severe pain (92.1%), in which 86.8% of patients sufferred from spinal pain, 71.1% of patients showed peripheral joint pain, commonly seen in hip joints (44.7%). Other common symptoms were lumbar Schober (about 3 cm), hand to ground distance (about 20 cm), median BASDAI score: 4.15 ± 1.01, median ASDAS-CRP: 3.81 ± 0.94, increasing CRP (81.58%), increasing erythrocyte sedimentation rate (81.6%), the percentage of HLA-B27 (+): 81.25% (for patients who have received this test). For patients treated with Fraizeron, in general, there were changes in patient global assessment, noctural back pain, peripheral swelling, lumbar Schober, hand to ground distance, BASDAI, ASDAS-CRP, erythrocyte sedimentation rate, CRP. These changes were positive with p < 0.05. When we assessed the safety of Secukinumab, we did not record any clinical or subclinical undesirable effects.

Conclusion: At week 16, Secukinumab has been effectively shown to improve clinical symptoms as well as subclinical symptoms in patients with AS. It is also considered safe for use in these patients.

Key words: Ankylosing Spondylitis, Secukinumab
THE EFFECTS OF ELECTROACUPUNCTURE COMBINED WITH ACUPRESSURE POINTS, MASSAGE TREATMENT AND “DOC HOAT TANG KY SINH” REMEDY ON TREATING SCIATICA DUE TO LUMBAR SPONDYLOSIS
Authors: Huynh Huong Giang , Nguyen Thi Tan , Nguyen Van Hung
Published: May 2021

Background: Sciatica due to lumbar spondylosis is a common disease syndrome, include pathological signs from lumbar spine and sciatic nerve. It occurs for a long time and affects to working ability and daily life. Currently there are many methods of treatment with modern medicine and traditional medicine. Electroacupuncture combined with acupressure point, massage treatment and “Doc hoat tang ky sinh” remedy is a highly effective method on treating sciatica due to lumbar spondylosis.

Objectives: To evaluate the effectives of electroacupuncture combined with acupressure point, massage treatment and “Doc hoat tang ky sinh” remedy on treating sciatica due to lumbar spondylosis.

Materials and Method: A total of 43 patients was diagnosed sciatica caused by lumbar spondylosis who treated at Thua Thien Hue Traditional Medicine Hospital. The study was designed by method of prospective study, assessed the results before and after the treatment.

Results: Very good: 34.9%; good: 34.9%; average 7%. There was not any unexpected effects observed in this trial.

Conclusion: Electroacupuncture combined with acupressure point, massage treatment and “Doc hoat tang ky sinh” remedy is a effective method on treating sciatica caused by lumbar spondylosis.

Key words: sciatica, lumbar spondylosis, acupuncture, electroacupuncture, acupressure point, massage treatment
Assessment of improvement on quality of life among patients undergoing surgery for treatment of degenerative lumbar spine in Quang Ngai General Hospital
Authors: Nguyen Hoang Lan , Truong Dinh Thong
Published: May 2021

Objectives: To compare quality of life of patients before and one- month after spinal surgery and to identify factors affecting improvement on their quality of life. Materials and Methods: A longitudinal study was conducted in 60 patients who were diagnosed with complicated degenerative lumbar spine and scheduled for surgery of spine at Quang Ngai General Hospital. The SF-36 scale was used to evaluate quality of life of the patients. Results: Findings showed that quality of life after surgery of patients was improved significantly in all components. The better change was found in items of bodily paint and social functioning while the least improvement was reported in physical functioning and role physical. Conclusion: Factors affecting improvement on quality of life of patients after degenerative lumbar surgery were age, BMI and accompanied diseases
Key words: degenerative lumbar disease, surgery, quality of life, SF-36, Quang Ngai
ASSESSMENT OF PATIENT’S SATISFACTION OF NURSING CARE PROVIDED BY CLINICAL DEPARTMENTS IN HUE UNIVERSITY OF MEDICINE AND PHARMACY HOSPITAL IN 2019
Authors: Doan Phuoc Thuoc , Duong Thi Hong Lien , Nguyen Viet Tu , Tran Thi Thanh Thao
Published: May 2021

Background: The quality of nursing care plays an important role in overall quality of medical care. Nurses and midwives perform care well, contributing to making patients feel secure, confident, cooperative, and increasing treatment efficiency and patient satisfaction. Objective: To assess the patient’s satisfaction with nursing care provided by clinical departments in Hue University of Medicine and Pharmacy Hospital in 2019. Subject and method: A cross-sectional study on 600 inpatients at Hue University of Medicine and Pharmacy Hospital. Results: The general proportion of patient statisfaction was 71.4%%. Patients were satisfied more with mental health services (77.8%), nursing care skills (75.5%) and the relationship with nurses (70.2%), consulting health education services (73.6%). Patient were less satisfied with hospital hygiene (61.5%). Conclusion: overall, more patient show enthusiasm with the medical care provided by nurse (71.4%). However, the patient’s satisfaction with hospital hygiene stood at only 61.5%.
Keywords: Quality of nursingcare, nurse, midwife
EVALUATION OF RISK FACTORS FOR THREATENED PRETERM LABOUR
Authors: Le Lam Huong , Truong Thi Linh Giang , Vo Hoang Lam , Ngo Thi Minh Thao , Dang Van Tan , Nguyen Minh Thang
Published: May 2021

Mục tiêu: Khảo sát một số yếu tố nguy cơ doạ sinh non. Phương pháp: Nghiên cứu mô tả cắt ngang có so sánh. Gồm 73 bệnh nhân được chẩn đoán dọa sinh non được theo dõi và điều trị tại khoa Phụ sản Bệnh viện Trung ương Huế từ tháng 06/2018 đến tháng 08/2019. Kết quả: Đa thai có nguy cơ dọa sinh non cao gấp 8,8 lần so với đơn thai 95%CI (1,2 - 82,7), đa ối nguy cơ dọa sinh non 4,9 lần 95%CI (1,1 - 23,9). Chiều dài CTC < 25 mm nguy cơ dọa sinh non cao hơn 4,2 lần 95% CI (1,3-13,1). Viêm đường sinh dục thấp tăng nguy cơ 2,6 lần ( 1,3 - 13,1) p < 0,05. Tuổi mẹ ≤ 20 hoặc > 35 có nguy cơ cao gấp 9,5 và 3,7 lần 95%CI (1,1 - 80,1) và (1,4 - 7,5). Thai phụ làm việc trên 40 giờ/tuần nguy cơ tăng 4,9 lần 95%CI (1,1 - 23,9), lao động nặng, môi trường làm việc ô nhiễm tăng nguy cơ 11,4 lần (1,4 - 91,7) và 8,8 lần (1,1 - 72,7). Sinh 3 lần dọa sinh non cao gấp 4,1 lần (1,3 - 13,1). BMI < 18,5 nguy cơ hơn 9,8 lần 95%CI (1,1 - 82,5); ≥ 23 tăng nguy cơ 4,4 lần (1,6 - 11,9). Tiền sử thai chết lưu, nạo thai, sẩy thai nguy cơ dọa sinh non tăng 6,9 lần 95%CI (1,5 - 22,4). Tiền sử sinh non, dọa sinh non nguy cơ tăng lên 9,1 lần 95%CI (2,0 - 41,7). Khoảng cách giữa hai lần mang thai < 12 tháng nguy cơ tăng 4,9 (1,0 - 23,9) lần. Kết luận: Phát hiện các yếu tố nguy cơ dọa sinh non để dự phòng sớm và theo dõi thai phụ tránh trình trạng dọa sinh non xảy ra là việc làm rất cần thiết.
Từ khóa: Dọa sinh non, phụ nữ mang thai, yếu tố nguy cơ.
SERUM FOLATE RECEPTOR ALPHA LEVELS IN PATIENTS OF EPITHELIAL OVARIAN CARCINOMA
Authors: Duong Thi Bich Thuan , Hoang Thi Lan , Hoang Anh Dung , Nguyen Dong Hai
Published: May 2021

High expression of FRA is observed in malignant epithelial ovarian tumors. This study is aimed to determine of serum folate receptor alpha levels in patients of epithelial ovarian carcinoma and to investigate the relationship between serum folate receptor alpha levels and serum CA125 levels and histopathological characteristics in patients of epithelial ovarian carcinoma. Materials and methods: Cross-sectional study was conducted on 26 patients with epithelial ovarian carcinoma and 56 patients with benign ovarian tumors. The subjects’ blood was collected to measure serum folate receptor alpha levels and serum CA125 levels. Information of clinical and subclinical characteristics were collected. Results: Median of serum folate receptor alpha levels in patients of epithelial ovarian carcinoma is higher than those with benign ovarian tumors (1683,0 compared with) 6.1, p < 0.001). With the cut-off point > 209.8 pg/mL, serum folate receptor alpha test has the diagnostic value of epithelial ovarian carcinoma with Se = 84.6%, Sp = 98.2%, PPV = 95, 65%, NPV = 93.22%, AUC = 0.978. Levels of serum alpha folate receptor were highly correlated to levels of serum CA125, tumor grade, and clinical stage of the disease. Conclusions: We suggest that serum alpha folate receptor is a highly promising biomarker for epithelial ovarian carcinoma.
Key words: serum folate receptor alpha, epithelial ovarian carcinoma.
TO STUDY OF CHARACTERISTICS OF OBJECTIVE MULTIPLE-CHOICE TEST FOR MEDICAL MODULES
Authors: Nguyen Truong An , Nguyen Minh Tu , Ngo Van Dong , Phan Van Thang , Ha Minh Phuong , Vo Phuc Anh , Tran Dang Xuan Ha , Nguyen Thi Nhat Hoa , Tran Thi Loi , Vo Ngoc Ha My , Le Thi Phuong Thuan , Nguyen Thi Tan , Vinh Khanh
Published: May 2021

Background: The objective multiple-choice test is an assessment method that has been applied widely in universities. The meticulous judgment of complication and differentiation level of objective test questionnaire can beneficially lead to the growth of high quality multiple-choice questionnaire bank and effective examination. Objectives: To evaluate the difficulty level and differentiate level of the objective multiple-choice tests. Materials and method: The multiple-choice theory test (01 Elemental medical exam with 242 students, 01 Clinical medicine exam with 163 students). The difficulty degree of questions was determined by calculating the percentage of students who gave the answers correctly for the given questions in total. The differentiation level was differentiated by the percentage of students who answered correctly in corresponding groups: excellent, good, average, below average, poor. Results: The elemental medical examination comprises 7 hard questions, 58 medium questions, and 35 simple questions; 10 questions have poor degree of difference, 83 questions have good and very good degree of difference. The clinical medicine examination comprises 9 hard questions, 57 medium questions and, 34 simple questions; 23 questions have poor degree of differentiation, 51 questions have good and very good degree of difference. Conclusions: It is crucial to evaluate the difficulty and differentiation standards of the objective multiple-choice examination which enhance the quality of assessment. Thereby, the faculties need to regularly judge these factors while creating the questionnaire and completely evaluating the tests, and the inappropriate questions will be eliminated.
Keywords: difficulty level, differentiation level, Objective multiple-choice test.
THE SURGICAL TREATMENT OF ACHALASIA ON LAPAROSCOPIC HELLER MYOTOMY WITH DOR ANTIREFLUX PROCEDURE AT HUE CENTRAL HOSPITAL
Authors: Phan Dinh Tuan Dung , Dang Ngoc Hung , Le Loc
Published: May 2021

Background: Achalasia is a primary motor disorder of the esophagus characterized by insufficient lower esophageal sphincter relaxation and loss of esophageal peristalsis. Diagnosis is confirmed by clinical symptoms, endoscopic, radiographic and manometric. Although pneumatic dilation has a role in the treatment of achalasia, laparoscopic Heller myotomy is considered by many experts as the best treatment modality for most patients with newly diagnosed achalasia. Objective: To evaluate the efficacy and safety of laparoscopic Heller myotomy with Dor antireflux procedure. Patients and Methods: Prospective analyses of the patients of achalasia undergoing laparoscopic Heller myotomy with Dor antireflux procedure from 01/2012 to 06/2020. We evaluated the data according to outcome measures, characteristics and treatment results of achalasia after laparoscopic Heller myotomy with Dor antireflux procedure. Results: We found 11 patients with achalasia were diagnosed and treated by laparoscopic. 100% of the patients have dysphagia, weight loss; 81.8% have chest pain and regurgitation. Mean operative duration was 148 ± 21 minutes. There was no complications had found in our patients. Follow-up after 3 - 6 months by Eckardt score show that 90.9% had a good result, 01 patient with persistent symtomps (Eckardt score > 3) had to undergo a pneumatic dilation. Conclusion: The results of the laparoscopic Heller myotomy with Dor antireflux procedure were safe and effective.
Keywwords: Achalasia, laparoscopic Heller myotomy, Dor antireflux procedure
CHARACTERISTICS OF SEXUALLY TRANSMITTED DISEASES IN DERMATOLOGY DEPARTMENT, HUE CENTRAL HOSPITAL
Authors: Mai Ba Hoang Anh , Bui Van Duy , Vo Tuong Thao Vy , Duong Huu Thanh , Tran Ngoc Khanh Nam
Published: May 2021

Background: Sexually transmitted diseases are popular, not only affecting the health but also affecting the psychology and social behavior of patients. After being diagnosed, the patients were hospitalized at the Department of Dermatology, Hue Central Hospital. Therefore, we conducted this study to investigate some characteristics of sexually transmitted diseases. Materials and methods: Cross-sectional study on 72 patients having one of sexually transmitted diseases,we investigated some characteristics and clinical forms. Results: The proportion of male and female was the same and the most common age group was 15-25 with 44.4%. Most patients had two or more sexual partners with 62.5% and very few often used condoms. Only three diseases were diagnosed with genital warts, syphilis and urethritis; among them genital warts was the most common 66.7%. Latent syphilis and small papules were the most common clinical forms of syphilis, condylomata acuminata, respectively. Conclusion: Sexually transmitted diseases were relatively common among inpatient diseases and had diverse characteristics.
Keywords: sexually transmitted diseases, gonorrhea, syphilis, condylomata acuminata
PREVALENCE OF DEPRESSIVE DISORDERS USING ICD 10 CLINICAL CRITERIA AND ASSOCIATION WITH HEALTH BEHAVIOR, TREATMENT ADHERENCE AND COMORBIDITIES AMONG PATIENTS WITH TYPE 2 DIABETES MELLITUS
Authors: Tran Nhu Minh Hang , Nguyen Quang Ngoc Linh , Vo Thi Han , Le Tran Tuan Anh
Published: May 2021

Background: The prevalence of depression is high in patients with type 2 diabetes mellitus (T2DM). Several studies showed that suitable health behavior and treatment adherance could be factors asociated with low prevalence of depression among patients with type 2 diabetes mellitus. Objectives: 1. To investigate the prevalence of depressive disorder using ICD10 clinical criteria among patients with T2DM. 2. To analyze the association between depressive disorder with health behavior, treatment adherence and commorbidities in the participants. Subjects and methods: This is a descriptive cross - sectional study on 210 inpatients with T2DM at the Department of General Internal Medicine, Hue University of Medicine and Pharmacy Hospital and at the Department of Endocrinology - Neurology, Hue Central Hospital. PHQ - 9 with the cutoff of 10 was used to screen depressed patients among participants, then psychiatrists used clinical criteria of ICD 10 to diagnose depression definitively. Patients who were diagnosed with depression according to clinical criteria were analyzed the association between depression with health behavior, treatment adherence and comorbidities by using univariable and multivariable logistic regression. Results: The prevalence of depressive disorder among patients with T2DM assessed by clinical criteria of ICD 10 was 31.4% in which severe (7.6%), moderate (19.5%) and mild depression (4.3%). Health behavior associated with depression in patients with T2DM are light or moderate activities such as practising yoga, walking, riding bicycle ... that help reduce the rate of depression, while working hard or playing heavy sports increases the rate of depression. In addition, patients with 2 or more complications, hypertension and kidney diseases increased the risk of depression in univariate analysis. The multivariate analysis of risk factors for depression were infectious diseases. Conclusion: Depression is found at a high rate among patients with T2DM. Light or moderate physical activity reduces the prevalence of depression. The complications and associated infectious disease are risk factors for depression. .
Key words: Depression, type 2 diabetes mellitus, health behavior, comorbidities, treatment adherence
SURVEY THE FREQUENCY OF CLINICAL SYMPTOMS ACCORDING TO TRADITIONAL MEDICINE IN PATIENTS WITH LOW BACK PAIN
Authors: Phan Thi Hong Nhung , Nguyen Thi Tan , Nguyen Van Hung
Published: May 2021

Background: Low back pain is a very common disease in daily life and clinical, which affects much to the health. Traditional medical symptoms of low back pain are very diverse and clinically difficult to diagnose. So we conduct this study to contribute to the standardization of symptoms according to traditional medicine and initially contributed to the improvement of diagnosis and treatment of diseases. Objectives: to survey the frequency of clinical symptoms according to traditional medicine in patients with low back pain and find out some factors related to the frequency of clinical types of the disease. Subjects and Methods: Including 92 patients were diagnosed with low back pain and treatment at the Traditional Medicine department of Hue Central Hospital and Thua Thien Hue Traditional Medicine Hospital. Research methodology is descriptive cross-sectional. Results: The symptoms of the tongue: 65.2% pale red tongue, 6.5% bluish purple tongue, 37.0% enlarged tongue, 8.7% thin tongue. About the tongue fur: 68.5% white fur and 31.5% yellow fur, 42.4% moist fur, 4.3% sticky slimy fur, 58.7% thin fur and 41.3% thick fur. The symptoms of the pulse: 17.4% floating pulse, 69.6% sunken pulse, nmoderate pulse 43.5%, powerful pulse 84.8%, weak pulse 15.2%. Among the patients have 33.7% constipation, 45.7% nocturia, 34.8% inability to sleep, 17.4% night sweating 12.0% spontaneous sweating. Conclusion: Symptoms: pale red tongue, white fur, moist fur, thin fur, constipation, nocturia, inability to sleep, sunken pulse, moderate pulse, powerful pulse have high rate; Symptoms have low rate such as bluish purple, the thin tongue, sticky slimy fur. There were significant relationships between clinical types and age, tongue color, tongue fur color, pain properties and pulse frequency (p < 0.05).
Key words: Low back pain, symptoms, traditional medicine.
STUDY ON CARDIOVASCULAR RISKS AND SERUM LEVELS OF NT-PROBNP IN&NBSP;
PATIENTS WITH PREECLAMPSIA
Authors: Nguyen Van Tri , Hoang Bui Bao , Huynh Van Minh
Published: May 2021

Survey serum levels of NT-proBNP and cardiovascular risks in patients with preeclampsia. Methods: A descriptive cross-sectional study. A survey of 52 women with preeclampsia in the Department of Gynecology and Obstetrics - Hue Central Hospital, from August 2019 to September 2020. Results: In preeclampsia patients, the rate of grade 3 hypertension was 46.1%, of grade 2 hypertension was 32.7%, of grade 1 hypertension was 21.2%. The average Sokolow-Lyon index in preeclampsia group with and without severe features was respectively 22.25 ± 7.38mm; 20.16 ± 5.54mm, the average Sokolow-Lyon index were not significantly higher in severe features preeclampsia group compared with without severe features preeclampsia group. The average LVMI in patients with and without severe features preeclampsia was respectively 120.68 ± 16.47g/m2; 92.27 ± 14.56g/m2 and the average EF in patients with and without severe features preeclampsia was respectively 56.21 ± 7.12%; 65.11 ± 3.45%. The average LVMI and the average EF were significantly higher in severe features preclampsia group compared with without severe features preclampsia group (p < 0.05). In additon, the average serum levels of NT-proBNP in patients with preeclampsia were 598.22 ± 234.35pg/ml. Serum NT-proBNP levels were significantly higher in the severe features preeclampsia groups than in the without severe features group (p < 0.05). Conclusion: The NT-proBNP level were statiscally significantly increased in the patients with preeclampsia. Preeclampsia patients are at increased risks of cardivacular diseases later in life. The serum NT-proBNP level appears to be useful marker to evaluate long-term cardivascular risks.
TWIN - TWIN TRANSFUSION SYNDROME AND TWIN ANEMIA POLYCYTHEMIA SEQUENCE: SCREENING, PREVALENCE, PATHOPHYSIOLOGY AND DIAGNOSIS
Authors: Truong Thi Linh Giang
Published: May 2021

Twin-twin transfusion syndrome (TTTS) and twin anemia polycythemia sequence (TAPS) are serious complications of monochorionic (MC) twin gestations. Only MC twins have these complications because, in contrast to dichorionic twins, the circulatory systems of almost all MC twins have arteriovenous (AV) anastomoses in the placenta, thus forming a vascular connection between them. TTTS - TTTS is characterized by relative hypovolemia of one twin and hypervolemia of the other as a result of many or large AV anastomoses deep in the placenta. The cardinal prenatal finding is MC placentation with discordant amniotic fluid volumes (maximum vertical pocket < 2 cm in one amniotic sac and > 8 cm in the other amniotic sac). TAPS - TAPS are an atypical chronic form of TTTS caused by slow transfusion of red blood cells through a few very small (< 1 mm diameter) placental AV anastomoses, resulting in anemia of one twin and polycythemia of the co-twin. Amniotic fluid volumes are normal. The cardinal prenatal finding is MC placentation with middle cerebral artery-peak systolic velocity greater than 1.5 multiples of median (MoM) in one twin and less than 0.8 MoM in the other twin. These descriptions reflect the characteristics of each disorder in its classic, pure form. However, diagnosis can be challenging because TAPS, TTTS, and a third disorder, selective intrauterine growth restriction (sIUGR), are not necessarily mutually exclusive of each other and can present together in any combination. This topic will review screening, prevalence, pathophysiology, and diagnosis of TTTS and TAPS. Management and outcome of patients with TTTS and TAPS, including neurodevelopmental outcomes, are discussed separately
COMPARISON OF MICROLEAKAGE IN CLASS V CAVITIES RESTORED BY GLASS IONOMER CEMENT AND COMPOSITE WITH OR WITHOUT PROTECTIVE COATING MATERIAL
Authors: Nguyen Thi Thuy Duon , Le Thi Hoai Phuong
Published: May 2021

Background: In order to treat cervical lesion of teeth, class V cavity is prepared and filled with restored materials. However, class V restoration is a common challenge to clinicians: low retention capacity, marginal defect and secondary caries due to microleakages. The aim of this study was to compare microleakage of class V cavities restored by glass ionomer cement and composite restoration with or without protective coating material.

Materials and Methods: 60 extracted premolars were randomly divided into 6 groups (n=10/ group). Each group were prepared and restored with one of three materials: conventional glass ionomer (CGIC), resin-modified glass ionomer (RMGIC) and composite, with or without G-Coat Plus. All samples were thermocycled, immersed in 0.5% Fuschin solution and evaluated microleakage by dye penetration.

Results: Gingival margin showed higher microleakage than occlusal margin in Composite group and CGIC groups with G-Coat Plus (p < 0.05). RMGIC showed lower microleakage than CGIC and Composite when assessed on gingival margin (p < 0.05). G-Coat Plus reduced the microleakage in the RMGIC and Composite groups when compared with the uncoated group (p < 0.05).

Conclusions: Microleakage depends on evaluated site and restored materials. Protective coating material reduces microleakage, especially on RMGIC and Composite restorations.

Key words: microleakage, class V cavity, glass ionomer cement, composite, provetive coating
BIOCHEMICAL AND VIRAL RESPONSE IN PATIENTS WITH CHRONIC HEPATITIS C GENOTYPE 1
Authors: Tran Van Huy , Tran Nguyen Ai Thanh
Published: May 2021

Background: The introduction of a new generation of direct acting antiviral agents (DAAs) is a revolution in the treatment of hepatitis C, opening the prospect of eliminating HCV in the future. In Vietnam, the combination of NS5A/NS5B drugs is officially circulated, which has very few studies assessing the therapeutic efficacy and drug tolerance of these drugs in hepatitis C. On the other hand, there are also fewer data on treatment efficiency of patients with genotype 1.6 in the world.

Objective: We survey clinical, biochemical and viral response in patients with hepatitis – C, genotype 1,6 treated with the combination of sofosbuvir and ledipasvir (LDV/SOF).

Methods: A prospective descriptive study was performed on 48 diagnosed patients who had chronic hepatitis C and/or compensated cirrhosis genotypes 1 or 6 and they were treated for 12 weeks with the combination of sofosbuvir and ledipasvir (LDV/SOF) at Internal Medicine Department, Thu Duc District Hospital.

Results: ALT decreased from 72.3 ± 31.9U/L to 29.4 ± 9.3 U/L, AST decreased from 72.9 ± 40.3U/L down to 35.2 ± 23.5 U/L after 12 months of treatment. Albumin and bilirubin maintained 3.64 ± 0.61 g/dL and 0.69 ± 0.26 g/dL. Platelets increase from 145.0 ± 36.3 to 173.9 ± 36.7 after treatment. Percentage of HCV RNA below threshold at the 4-week period later treatment achieved 93.3% and reached 95.5% achieved by SVR12. The incidence of drug side effects is 18.7%. Most are mild, transient symptoms such as fatigue, nausea, diarrhea or loss of appetite...

Conclusion: LDV/SOF is an effective, improved interferonfree treatment, good biochemical and microbiological aspects. LDV/SOF therapy is safe and has little effect serious side effects due to medication.

Key words: chronic hepatitis C, ledipasvir, sofosbuvir, viral response
ESTIMATION OF PV MODULE PARAMETERS USING GENERALIZED HOPFIELD NEURAL NETWORK
Authors: Dharmarajan Ranjith , Ramachandran Rajeswari
Published: May 2021

The estimation of solar photovoltaic (PV) system with help of electrical model parameters, suchas photon generated current, the diode saturation current, series resistance, shunt resistance, anddiode ideality factor, are desirable to predict the real performance characteristics of solar PVunder varying environmental conditions. Finally, performance indices, such as PV characteristicscurve are estimated for the various solar PV panels using GHNN optimization technique.
Experimental investigation on strength properties of concrete using polypropylene pellets
Authors: G Anand , M Velumani , S Sakthivel
Published: May 2021

The handmade tiles are manufactured in Athangudi, Sivagangai district. We observed that these tiles are reducing foot pain and appearing aesthetic look. But one disadvantage was that these Athangudi tiles were getting easily cracked. We studied that these tiles are getting cracks. Due to its lesser resistance. It shows some cracks on surface of tiles after setting and hardening process. In this project, we gave solution to rectify the problem for this purpose we adding the zirconium di oxide to cement paste at the time of manufacturing process. Because the zirconium di oxide possess high crack resistance property in these tiles. The field test (water penetration test), abrasion test, water absorption test and acid resistance test were conducted on Athangudi tiles with zirconium di oxide and without zirconium di oxide. Then the test result was compared between normal tiles and zirconium di oxide used tiles. Hence we conclude that zirconium di oxide used tiles are somewhat better than normal Athangudi tiles from the above result. We will conduct more tests and come with the conclusion that zirconium di oxide used tiles having better cracking resistance in future.
Evaluation of Dissociation Energies of the Diatomic (NdO, FeH and BaF) Molecules
Authors: Raju Linga , M S Ramesha
Published: May 2021

The ground and excited state dissociation energies are determined by curve fitting techniques using the five parameters Hulburt-Hirschfelder (H-H) function. The estimated dissociation energies are 7.33± 0.15eV, 2.90 ± 0.13 eV and 6.04± 0.12eV for NdO, FeH and BaF respectively. The computed values are in good agreement with the literature values. The nature of binding is discussed in the light of the percentage ionic\characters of these molecules.
Influence of Gender on Psychological Wellbeing among Elderly Working And Nonworking Respondents
Authors: M S Rekha
Published: May 2021

Retirement tends to be perceived by society as passivity, social withdrawal, and physical and mental decline. The fact that people in retirement have withdrawn from economic endeavor tends to lower the esteem in which they are held by the community even though the withdrawal may be forced upon the individual by reason of compulsory retirement at a fixed age. These are the negative aspects of the overall picture. Keeping this as background an attempt is made to assess “Influence of Gender on Psychological Wellbeing among Elderly Working And Nonworking Respondents”.For the study purpose 309 elderly persons were included, 199 were male and remaining 110 were female. Among them retired working male were 99 and retired nonworking male were 100 and retired working female were 29 and retired nonworking female 81. Psychological wellbeing scale by Sisodia and Choudhary (2012) measuring 5 aspects namely life satisfaction, efficiency, sociability, mental health and interpersonal relations was used to measure the level of psychological wellbeing among retired working and non-working persons. Two-way ANOVA was employed to find out the impact of gender on psychological well-being. Results revealed that male respondents had better psychological wellbeing than female respondents. However, the interaction effect between groups and gender was found to be significant indicating male and female respondent differed significantly in total psychological wellbeing irrespective of the group they belong. Thus there is an impact of gender on psychological well-being among elderly working and nonworking persons. Engaging in life, financial benefit and social contacts even after retirement balance the wellbeing in elderly leading to happy and successful aging.
Legal Framework to Protect the Rights of Migrant Workers: A Study with Reference to India
Authors: A Narayanaswamy
Published: May 2021

In modern days right to life, freedom of profession and freedom of movement are recognised as a universal fundamental human rights, which are also interrelated and inter connected with each other. Universally, all human beings are equally entitled to enjoy all such rights. Indeed, migrant workers are also part of a human society who are not exceptional to enjoy all such rights. However, due to migration, migrant workers are marginalised and vulnerable groups. Perhaps, migrant workers are poor, illiterate and backward in all means. In this juncture, they have been exploited, discriminated and deprived to enjoy and access all such human rights equally compare to other non-migrant human beings across the globe. After the establishment of ILO and UNO, there are several International Declarations, Covenants and Conventional provisions etc.., which are equally applicable to all states across the globe including India to protect the rights of migrant workers. Similarly, in India also Constitutional provisions and legislative measures adopted, but due to failure to implement the above provisions effectively, migrant workers have been facing a lot of problems in inter-state and intra-state migration. Therefore, it is an attempt to know how for the rights of migrant workers have been safeguarded internationally and nationally. For this purpose the researcher has framed the following objectives.

Objectives

The Researcher has framed the following objectives,

To know the International legal frame work and how it protects the rights of migrant workers.

To examine the Indian legal system to protect the rights of migrant workers.

To know the causes, modes, problems and challenges of migrant workers.

Suitable suggestions to protect the rights of migrant workers.
Human Resilience in the Short Stories of Yashwantha Chittala
Authors: N S Sindhu
Published: May 2021

Life has been an inspiration for the birth of several philosophies and streams of study from time immemorial.
Indo - English Novels Amalgamation of Indian Tradition and World Tradition
Authors: G S Dayananda Sagar
Published: May 2021

In India the novel is the readiest and most acceptable way of embodying experiences and ideas in the context of our time.The duality of Indo-English fiction has been attracting worldwide attention. One wonders whether the Indo-English novel is a part of the Indian tradition or the European tradition or of the abstract world tradition.The Indo-English fiction in Post-independent India assumed over the preceding thirty years all kinds of colorful traditions. It is now free from the social yard political overtones of a rabidly nationalistic variety.As regards the theme of the novel, in the late Twentieth Century alienation has significantly affected the Indo-English novel. It has served as a recurrent motif in quite a few works produced by Indian novelists in English. It is also the dominant trait of several characters created by the novelists.
An Overview of Stress Management
Authors: Ameena Bi Bi
Published: May 2021

Stress is extremely complex. The state of the body and that of the mind are closely related. When we start to examine what that “something” is, it gets complex. Stress produces a state of physical and mental tension and frustration. Stress is not necessarily something bad, it is also positive and all depends on how we take it. If the mind is relaxed we can see, the muscles in the body will also be relaxed. Some stress can be useful. Stress is a normal, general and universal reaction to life events. It is what you feel when life demands more than you handle. Stress occurs too long or too often which causes problems. It can affect our normal daily routine. Too much stress increases the risk for mental and physical illness and weakens immune system. Stress problems are highly common with many people reporting experiencing extreme levels of distress or negative stress. Being “stressed out” is thus a common or universal human phenomenon that has an impact on almost everyone. When we have lot to do to, we tend to feel much more stressed out. Most people use the word stress to refer to negative experiences which leave us feeling submerged and unpleasant. Only few people enjoy the feeling of being overwhelmingly stressed in the face of great change. Our experiences and feeling of stressed varies in intensity between high, medium and low. People do not like experiencing the peak of stress. Meditation and yoga is recognised as a form of mind-body medicine and a very good relaxation technique. Even exercising has a very good benefit in relaxing the mind and body. We tend to ignore the difficulties of how and why stress makes us feel depressed, exhausted and function the way it does.Suitable and appropriate amount of stress can actually stimulate passion for work, tap hidden abilities and even provoke, ignite inspirations. Stress can make a person creative, productive and constructive, when it is identified and well managed.
Virutal Reality Tourism - Exploring New Possibilities Amid Covid-19 Pandemic
Authors: H N Vidya
Published: May 2021

This paper explores the tourism trends emerging in post COVID- world. This pandemic was conscientious for an abrupt transformation in the way world travelled. This impulsive impediment in the tourism and hospitality industry was not only unconstructive to the growth of the industry but the imminent influences on future tourism are also looking dim and muted. Virtual Reality has emerged as a new innovative approach to attract viewers though providing them a virtual experience of tourism a tour destination with enhanced technological version. Virtual reality is the new normal in the digital world. People are slowly gaining access to digital tourism experiences through Virtual Reality tourism concept. The increase in virtual reality tourism trend is most welcome thing globally. This trend capitalizes on the use of technology to make viewers experience a touring destination. It includes Virtual Reality tours through which a tourist or viewer can experience a tourist destination, hotel interiors, restaurant interiors, outdoor tourist attractions, shopping sites, archaeological inputs, museums, etc sitting in home. This viewer is made to experience complete visit of the destination through VR head gears and comply with his aspirations of touring. Without being physically present on the tourist site a viewer can become a tourist and see all sites as naturally as a tourister. But this usage of technology driven virtual reality tools are challenged by several factors.