bluuebunny/crossref_metadata_2025 huggingface dataset:
Çumra- Konya Bölgesindeki Yüksek Genlikli Gravite Anomalilerine Neden Olan Yapıların Araştırılması
Authors: Erbek Ezgi , Dolmaz M. Nuri
Published: December 2019

Konya ili sınırları içerisinde yer alan Çumra
bölgesindeki yüksek gravite anomalilerinin nedeni olan yapılar spektral analiz
ve yapı sınırı yöntemleri ile araştırılmıştır. Gravite verilerinin güç
spektrumundan anomalilere neden olan yapıların ortalama derinlikleri
hesaplanmıştır. Tilt açısı yöntemi ile ise bu yapıların sınırları ve üst yüzey
derinlik değerleri belirlenmiştir. Gravite verilerine uygulanan analitik sinyal
yönteminden yararlanılarak elde edilen tahmini taban derinlik dağılım
haritasında derinlik değerlerinin 1.6 km ile 9.4 km arasında değiştiği
görülmektedir.
Herança da informação digital e direito ao esquecimento em redes sociais on-line: uma revisão sistemática de literatura
Authors: Silva Simone de Assis Alves , Maia Luiz Cláudio Gomes , Rafacho Rafael Lelis , Pereira André Luiz Ogando , Alto Paulo Sérgio Monte
Published: December 2019

Com a evolução e a expansão da Internet, pode-se observar a criação e a difusão das redes sociais on-line, que são serviços digitais para conectar diferentes usuários por meio de perfis públicos ou semipúblicos. Nesse cenário, iniciam-se os estudos acerca das redes sociais e de seus desdobramentos na sociedade, como a herança digital, entendida como o acervo digital (fotos, mensagens, vídeos etc.) deixados em vida pelo usuário. Após a inatividade do perfil de um usuário devido ao seu falecimento, é importante dar o devido tratamento a essa herança deixada por ele. Assim, aparece como dispositivo legal o Direito ao Esquecimento, que em seu cerne conceitual propõe ora o direito ao acesso a informação e liberdade de expressão ora o direito à intimidade e à privacidade, capaz de resguardar ao titular de determinado dado a faculdade de vê-lo apagado, suprimido ou bloqueado. O presente artigo apresenta o resultado de uma Revisão Sistemática de Literatura, com o propósito de verificar o atual cenário de pesquisa sobre o direito ao esquecimento e herança digital no contexto das redes sociais on-line e identificar sob qual enfoque os estudos estão sendo realizados. Foi possível auferir que, no atual cenário de uma sociedade permeada pelos recursos oferecidos pelas Tecnologias da Informação e Comunicação, a maior parte das pesquisas concentra-se nos princípios da intimidade e privacidade sob a prerrogativa do indivíduo frente a essa nova sociedade, o qual exige respostas rápidas e legítimas para a preservação de sua imagem e personalidade nos espaços por onde ele passar.
PPM de flúor rotulado y analizado en pastas dentales pediátricas comercializadas en Lima-Perú
Authors: Córdova-López Ofelia , Hermoza-Moquillaza Rocío Victoria , Darwin Yanac Calero Darwin Yanac Calero , Arellano-Sacramento César
Published: December 2019

Objetivos: Determinar la concentración de ppm de ﬂúor en pastas dentales para niños que se comercializan en Lima Perú en el año 2017. Material y métodos: Es un estudio observacional, descriptivo, transversal. Fueron recolectadas 48 pastas dentales pediátricas vendidas en establecimientos farmacéuticos (farmacias y boticas) de Lima. Se empleó las pruebas de t de Student y Wilcoxon para una sola muestra. Resultados: La diferencia entre la concentración de ﬂúor según rotulado y encontrado en Colgate de 1 100 ppm fue -119,8 ppm (mediana), Oral B de 500 ppm fue de -57,05 ppm (mediana). La diferencia entre la concentración de ﬂúor según rotulado y lo en- contrado en base al promedio fue Colgate de 500 ppm: -34,2 ppm, Farmadent de 452 ppm: -36,27 ppm, Dentito de 550 ppm : -520,1 ppm, Aqua fresh de 500 ppm: +41,67 ppm, Vitis de 1 000 ppm: +141,85 ppm, Aqua Fresh de 1 150 ppm: +112.82 ppm; de entre los mencionados sólo Aqua Fresh de 500 ppm fue no signiﬁcativo. Con respecto al pH de las pastas dentales, los promedios fueron 5,92; 5,5; 5,5; 6; 6; 5,5; 5,5; 6, respectivamente. Conclusiones: Cinco tipos de pastas dentales tienen concentraciones menores al rotulado, y tres tipos de pastas dentales tienen concentraciones mayores al rotulado (de las cuales una no fue signiﬁcativa).
Temores y desafíos actuales sobre la Radiología Oral y Maxilofacial
Authors: Tisi José Pablo
Published: December 2019

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EXTRACTION OF KETAPANG SEEDS (TERMINALIA CATAPPA LINN) AS RAW MATERIAL OF BIODIESEL
Authors: Putri Novy Pralisa , Muslim Muhammad Affandhy , Sitorus Joel Gerystra , Putra Dicky Luhangga , Marjenah Marjenah
Published: December 2019

Abstract- Terminalia catappa Linn. (ketapang) is a coastal tree with a widespread area. Its derived from the tropics of India, and spread to Southeast Asia, Northern Australia and Polynesia in the Pacific Ocean. This study aims to determine the effect of maceration time on the density of the species, yield, and % FFA from oil of ketapang. The research procedure is done by soaking ketapang seed powder wrapped with filter paper into a chemical glass containing 500 mL of n-Hexane solvent. Then the solvent which has been mixed with oil, separated by distillation. Variables used in this research is the variation of immersion time in the unit of day. The results of the research are 25-31 mL of oil volume, yield percentage of 0.44-0.52, density of 0.84-0.88 g / mL, 28-35% percentage of FFA. Ketapang oil obtained a lot of fatty acids that can be used as raw materials for making biodiesel but it needs to be pre-esterification first to reduce levels of FFA up to 2%. Keywords:      FFA, Ketapang Oil, Maseration, Yield
THE UTILIZED OF ULIN WOOD WASTE (Eusideroxylon Zwageri T) AS ACTIVE CHARCOAL TO ADSORB IRON (Fe) AND MANGANESE (Mn)
Authors: Mirwan Agus , Pratidina Niska Nana , Sari Anna Permana
Published: December 2019

Abstract- A research on the utilization of ulin wood waste (Eusideroxylon Zwageri T) has been conducted as an active charcoal to adsorb Iron (Fe) and Manganese (Mn). The purpose of this research is to know and study the potential of activated charcoal from Ulin wood waste as adsorbent of Iron (Fe) and Manganese (Mn) in well water, knowing optimum time to adsorb Iron (Fe) and Manganese (Mn) and to know the concentration of Iron (Fe) and Manganese (Mn) after adsorbed by activated charcoal from Ulin wood waste. Charcoal is obtained from Ulin wood with burning for 9 hours, then activated chemically and physics. The parameters studied were pH, optimum time determination, Iron (Fe) and Manganese (Mn) concentration after adsorption. The results showed that the optimum time (toptimum) to adsorb Iron (Fe) and Manganese (Mn) was at minute 30 and obtained the optimum concentration of Iron (Fe) of 0,22 mg / L and Manganese (Mn)  concentration of 0,174 mg / L . Keywords: Ulin Wood, activated charcoal, Fe and Mn adsorption, filtration.
PENGARUH PENAMBAHAN DUAL KATALIS PADA SILICA-CARBON XEROGEL SEBAGAI MATERIAL PELAPIS ORGANO SILICA MEMBRANES
Authors: Elma Muthia , Paramita Adhe , Sumardi Anna
Published: December 2019

Abstrak- Proses sol-gel adalah proses polimerisasi senyawa kimia (precursor) melalui reaksi hidrolisis dan kondensasi dalam larutan pada suhu rendah. Nlai pH mempengaruhi daya larut precursor dan rasio konfigurasi ion yang dapat larut dan mengendap. Secara fundamental larutan sol yang memiliki pH > 7 akan memiliki morfologi  makroskopik sedangkan pH < 7 memiliki morfologi mikroskopik. Tujuan dari penelitian ini adalah untuk menentukan kondisi optimum dari thin film yang dihasilkan dari proses sol-gel yang nantinya bisa diaplikasikan sebagai pelapis pada membrane organo-silica untuk proses desalinasi air asin. Metode yang digunakan pada penelitian ini adalah sol-gel menggunakan dua katalis (basa dan asam organik), dengan perbandingan 1:38:X:5:Y (molar rasio). Dimana X:Y adalah asam sitrat (C6H8O7):ammonia (NH3). Perbandingan molar rasio katalis asam sitrat:ammonia yaitu 0.01 : (0.01; 0.0015; 0.001)  dan 0.001 : (0.01; 0.0015; 0.001) dengan suhu proses 0OC. Hasilnya dikarakterisasi menggunakan uji FTIR. Hasil penelitian ini menunjukkan semakin rendah katalis molar rasio asam sitrat maka pH yang didapatkan semakin tinggi dan ukuran pori-pori semakin besar. Sampel menghasilkan pH berkisar 5,32-8,56. Pada pH asam menghasilkan silanol (2.0) dan siloxane (7.4) sedangkan pada pH basa menghasilkan silanol (1.7) dan dan siloxane (6.2). Jadi, sols optimum sebagai thin film yang dihasilkan adalah pada pH 6.0 yang memiliki silanol (1.0) dan siloxane (4.7) dengan kalsinasi xerogel yang optimum terdapat pada suhu kaslinasi 175OC, karena adanya kandungan ikatan karbon yaitu struktur C=C-H (alkena) pada peak 3750cm-1. Ikatan karbon pada membran dapat membuat membran stabil.  Kata kunci: ammonia, citrit acid, silica-carbon thin film, xerogel
EFFECTS OF TEMPERATURE-pH ON LIQUID PHASE MASS TRANSFER AND DIFFUSION COEFFICIENTS AT LEACHATE TREATMENT IN ANAEROBIC BIOREACTOR
Authors: Kahar Abdul , Warmadewanthi IDAA , Hermana Joni
Published: December 2019

Abstract - Leachate contains complex dissolved organic and inorganic substrates that are biodegradable and non-biodegradable. Principally, anaerobic treatment utilizes anaerobic bacteria to degrade the dissolved organic matters. Anaerobic treatment is very sensitive towards the change of temperature and pH. This research used an anaerobic bioreactor with volume of 160L, with a ratio of leachate:biogas was 70:30. Seeding, acclimatization and leachate treatment were executed at temperature 35°C; pH ambient, temperature 45°C; pH ambient, temperature 35°C; pH 7.2 and temperature 45°C; pH 8.0. Based on this research, that there is dependency on mass of solutes organic substrate (COD) in the leachate, at all operating conditions of leachate treatment in anaerobic bioreactor. Hence, the organic substrate concentration (COD) will affect the VFA, the liquid phase mass transfer and diffusion of solute organic. Consequently, the higher the temperature-pH, the higher the liquid-phase mass transfer, but lower diffusion coefficients is. Keywords: anaerobic bioreactor, diffusion, leachate, liquid-phase mass transfer
PEMURNIAN BIOETHANOL DENGAN METODE DISTILASI AZEOTROP
Authors: Sriana Tun
Published: December 2019

Abstrak- Bioethanol merupakan salah satu sumber energi alternatif yang sangat berpeluang untuk dikembangkan di Indonesia. Selain sebagai bahan baku alam yang dapat diperbaharui dan bersifat ramah lingkungan, bioethanol juga dapat dimanfaatkan sebagai bahan bakar substitutif maupun aditif pada bahan bakar fosil. Namun kenyataannya bioethanol hasil fermentasi hanya mempunyai kadar ethanol sebesar 10-15%, sedangkan untuk dapat digunakan sebagai bahan bakar atau bahan substitusi bioethanol harus mempunyai kemurnian mencapai 99,5%.  Dalam proses pemurniannya, air yang terdapat pada bioethanol akan membuat campuran azeotrop sehingga sulit dipisahkan dengan proses distilasi biasa. Salah satu metode pemisahan untuk memisahkan campuran azeotrop adalah dengan menggunakan metode distilasi azeotrop. Pada distilas ini akan ditambahkan entrainer yaitu zat yang berperan mengubah volatilitas relatif komponen kunci. Untuk menaikan kadar bioethanol dan mengetahui pengaruh entrainer pada distilasi azeotrop digunakan dua jenis entrainer yaitu benzene dan n-heptane. Dari hasil penelitian didapatkan bahwa benzene yang mempunyai gugus aromatik dapat menaikan kadar ethanol lebih baik dibadingkan dengan n-heptane dan cyclohexane.        Keywords: bioethanol, distilasi azeotrop, entrainer, benzene, n-heptane
KARAKTERISASI XEROGEL SILIKA-ORGANIK YANG BERASAL DARI GLUKOSA
Authors: Elma Muthia , Mujiyanti Dwi Rasy , Amalia Mufidah Nur
Published: December 2019

Abstrak- Telah dilakukan penelitian tentang karakterisasi xerogel silika-organik yang berasal dari glukosa sebagai templet. Tujuan dari penelitian ini untuk mempelajari karakter dan struktur dari xerogel silika-glukosa templet yang akan digunakan sebagai thin-film dalam pembuatan membran. Xerogel dibuat melalui proses sol-gel ini adalah dengan menggunakan TEOS (tetraetil ortosilikat); etanol; asam nitrat; ammonia; aquadest  dan glukosa sebagai template. Dengan perbandingan molar rationya adalah 1:38:0.0007:0.0003:5 dan 0.25%; 0,5%, 1% b/v glukosa sebagai templet. Sols yang dihasilkan dikeringkan di oven dan dikalsinasi pada temperatur kalsinasi sebesar 400oC (dalam bentuk xerogel). Xerogel ini selanjutnya dikarakterisasi dengan menggunakan FTIR untuk menentukan perubahan gugus fungsi dari masing-masing konsentrasi molar ratio dari glukosa. Hasil penelitian menunjukkan bahwa gugus Si-OH (Silanol) ditemui pada bilangan gelombang 950 cm-1 dan gugus Si-O-Si (Siloksan) pada bilangan gelombang 1070 cm-1 dan 1160 cm-1. Sementara itu, gugus Si-C bisa ditemui pada bilangan gelombang 760 cm-1. Dengan menggunakan metode dekonvuasi pada aplikasi fityk, dari ketiga konsentrasi glukosa templet dihasilkan jumlah silanol tertinggi berada pada konsentrasi glukosa 0.25% begitu juga dengan konsentrasi siloksan tertinggi dijumpai pada penambahan glukosa pada konsentrasi 0.25%. Ini menunjukan bahwa terlihat jelas struktur gabungan matriks silika-glukosa akan semakin besar dengan ditingkatkannya konsentrasi glukosa sebagai templet. Ikatan karbon ini membantu mengganti ikatan –OH pada silanol menjadi ikatan Si-C. Akibatnya struktur silika matriks akan semakin kuat dan sangat membantu mempertahankan struktur silika matriks jika diaplikasikan nantinya sebagai pelapis membran. Kata Kunci: xerogel silika-glukosa, proses sol-gel, dekonvulasi
TEKNOLOGI MEMBRAN ORGANO-SILICA UNTUK DESALINASI AIR ASAM TAMBANG
Authors: Elma Muthia , Sari Norlian Ledyana , Pratomo Dhimas Ari
Published: December 2019

Abstrak- Pengolahan air asam tambang merupakan pengolahan air yang sangat dibutuhkan untuk membantu ketersediaan air bersih. Teknologi pengolahan air ini salah satunya adalah menggunakan teknologi membran (membran organo-silica) secara teknik desalinasi. Tujuan penelitian ini adalah untuk menentukan performansi organo silica membrane menggunakan katalis organik. Untuk membuat thin film sebagai pelapis membran digunakan metode sol-gel dengan precursor tetra ethyl orthosilicate (TEOS). Thin film ini selanjutnya di dipcoating ke membrane support sebanyak 4 layer dan dikalsinasi pada suhu 200, 250 dan 600 oC. Teknik desalinasi yang digunakan adalah berupa proses pervaporasi dengan menggunakan artificial brine water (5%, 7,5%, 10% dan 15%) sebagai air umpan. Hasil penelitian menunjukan bahwa nilai water flux adalah sebesar 0.39; 0.44 dan 0.82 kg m-2 h-1  (untuk thin film membran yang menggunakan suhu 50oC) dengan nilai salt rejection sebesar ~100 % untuk setiap membran. Nilai water flux ini berturut-turut untuk membran yang dikalsinasi pada suhu 200, 250 dan 600 oC). Dari hasil water flux dan salt rejection diketahui bawa membran yang dikalsinasi pada suhu 600oC memberikan nilai water flux tertinggi walaupun semua membrane memberikan nilai salt rejection yang mendekati 100%). Jenis membrane ini berkemungkinan memberikan ukuran pori-pori yang agak besar karena kandungan carbon yang sudah terikat pada struktur silika sudah terdekomposisi sempurna pada suhu tinggi, sehingga menambah besar ukuran pori-pori dari struktur silika. Ukuran pori-pori ini menyebabkan nilai water flux menjadi lebih tinggi. Kata kunci: brine water, flux, reflux, salt rejection, pervaporasi
POTENSI ASAP CAIR PADA PRODUKSI ARANG KAYU MODEL DESA RANGGANG TANAH LAUT
Authors: Junaidi Ahmad Budi Budi , Abdullah Abdullah , Santoso Uripto Trisno
Published: December 2019

Abstrak- Desa ranggang merupakan sentra produksi arang kayu di Kalimantan Selatan. Arang kayu diproduksi dalam tungku dari tanah liat berbentuk kubah dengan diameter sekitar 4 meter dan tinggi 3-4 meter. Di Desa Ranggang ini terdapat lebih dari 500 buah tungku dengan kapasitas produksi arang kayu sekitar 2-3 ton arang/tungku untuk tiap kali produksi. Asap yang keluar dari tungku arang pada proses produksi arang jumlahnya sangat besar selama ini terlepas ke lingkungan yang berpotensi menimbulkan polusi udara dan mengganggu pengrajin arang tersebut.. Penelitian tentang potensi asap cair sebagai produk samping pembuatan arang kayu desa ranggang tersebut dilakukan dengan memodifikasi model tungku arang desa Ranggang berupa penambahan instalasi kondensasi asap pada bagian knalpot tungku. Tungku arang percontohan telah dibuat dengan kapasitas produksi 3 ton arang setiap kali produksi. Bahan baku yang digunakan adalah limbah kayu ulin (Eusideroxylon zwageri Teijsm. & Binn.). Asap cair yang diperoleh dari tungku tersebut sejumlah 47 liter untuk setiap kali produksi. Asap cair yang dihasilkan didominasi fraksi suhu 95-105 0C, yaitu sebanyak 81%, memiliki kadar  asam (dihitung sebagai asam asetat) 0,825 molar dengan pH berkisar. 2,91-3,08. Kata kunci: asap cair, produk samping, produksi arang, kondensasi asap dan tungku arang Ranggang
MANUFACTURING OF BIOPLASTICS FROM CELLULOSE EMPTY FRUIT BUNCHES WASTE WITH ADDITION OF GLYCEROL AS PLASTICIZER
Authors: Amalia Azahra Rizka , Kumara Rian Fasya , Putri Novy Pralisa
Published: December 2019

Abstrak- Produksi sampah plastik meningkat setiap hari dan dapat merusak lingkungan karena plastik sulit terurai. Oleh karena itu mengurangi penggunaan plastik atau mengganti bahan baku plastik adalah salah satu solusi untuk masalah lingkungan. Selulosa adalah salah satu bahan pembentuk plastik dan salah satu sumber selulosa adalah tandan kosong kelapa sawit. Selulosa diekstraksi dari limbah tandan buah kosong menggunakan metode delignifikasi dengan larutan NaOH 17,5% selama 3 jam pada suhu 90-95˚C. Sintesis bioplastik diproses dengan selulosa, pati dan gliserol. Metode sintesis yang digunakan adalah pemanasan selama 1 jam pada suhu 80-90˚C. Variabel yang dianalisis adalah variasi selulosa dan massa pati 0,4 g dan 0,8 g; 0,5 g dan 0,7 g; 0,6 g dan 0,6 g; 0,7 g dan 0,5 g; dan 0,8 g dan 0,4 g. Tes bioplastik yang dilakukan meliputi uji ketahanan air, uji kepadatan, dan uji biodegradasi. Hasil yang paling optimal dalam uji ketahanan air adalah 29,17%, uji kepadatan 0,7273 g mL, dan uji biodegradasi adalah 19,58%.  Keywords :  tandan kosong kelapa sawit, selulosa, delignifikasi, sintesa, bioplastik.
ISOLATION OF MICROCRYSTALLINE CELLULOSE FROM MEDANG WOOD (Neolitsea latifolia)
Authors: Sunardi Sunardi , Lestari Amelia , Junaidi Ahmad Budi , Istikowati Wiwin Tyas
Published: December 2019

Abstract - Research on the effect of the use of HCl concentrations in the hydrolysis process of cellulose from medang wood (Neolitsea latifolia) on the characteristics of microcrystalline cellulose has been studied. The purpose of this study was to determine the effect of HCl concentration on the characteristics of microcrystalline cellulose. The analysis carried out included yield, pH, color, functional group characterization using FTIR and crystallinity index using XRD. The hydrolysis process was carried out at 105 °C for 15 minutes with variations in HCl concentrations of 1.5 N, 2.5 N and 3.5 N. Based on the results of the research conducted, the results showed that the use of variations in the concentration of HCl in the hydrolysis process affected the yield, color, TCI (Total Crystallinity Index) value of FTIR data and crystallinity index of XRD data. The yield of microcrystalline cellulose produced from each variation of concentration was 64.41, 61.94 and 53.99. The color of microcrystalline cellulose is getting darker as the concentration of HCl is used. Based on FTIR data, the TCl value of microcrystalline cellulose from each variation of concentration was 0.861%, 0.907% and 0.976%. XRD data shows an increase in crystallinity index produced from each variation in concentration on microcrystalline cellulose amounted to 80.52%, 82.17% and 83.49%.
PYROLYSIS OF CASSAVA BAGASSE INTO BIO-OIL USING Ni/NZA CATALYSTS
Authors: Jefriadi Jefriadi , Bahri Syaiful , Sunarno Sunarno , Jelita Rinny
Published: December 2019

Cassava bagasse is a solid tapioca industry waste that can be used as an energy source. In this study, cassava bagasse was pyrolyzed to produce bio-oil and studied the effect of Ni/NZA catalysts on yield, heating value and distribution of bio-oil products. The making of Ni/NZA catalyst starts with the process of activating natural zeolite to produce natural zeolite activated (NZA). Furthermore, impregnation of Ni metals in NZA with Ni levels 1, 2 and 3% w/w (Ni/NZA). The next step is calcination, oxidation and reduction. Cassava is peeled, shredded, washed, filtered and dried and then mashed and screened with a 60 and 80 mesh sieve to obtain cassava bagasse biomass with a size of -60+80 mesh. 50 grams of cassava bagasse with 500 ml silinap and 1.5 gram Ni/NZA catalyst are pyrolyzed at 320oC with nitrogen gas flow of 80 mL/min. Bio-oil products are analyzed by the heating value and distribution of the products. The yield of bio-oil obtained on pyrolysis using 0% Ni/NZA was 54.27% and pyrolysis using 2% Ni/NZA obtained the highest yield of 61.87%. The highest bio-oil heating value was obtained in pyrolysis using 0% Ni/NZA which is 46.78 MJ/kg and lower with increasing Ni levels in NZA. The results of GC-MS analysis of the bio-oil products showed that the use of 1% Ni/NZA catalyst significantly increased the percent area of several components i.e. 2,4,4-trimethy-l-1-Pentene, 2,5-dimethyl-2,4-Hexadiene, and 2,4,4-trimethyl-2-Pentene and decreases the percent area of some other components i.e. 1-bromo-3-methyl-Cyclohexane, 2-methyl-1-Propene,tetramer, 1-(1,1-dimethylethoxy)-3-methyl-Cyclohexene and 3-(3,3-dimethylbutyl)-Cyclohexanone.
ANALYSIS OF ENCAPSULATED YEAST IN COMPUTATIONAL FLUID DYNAMICS APPROACH
Authors: Lestari Riani Ayu , Lestari Rianti Indah
Published: December 2019

Abstract - Computational fluid dynamics of encapsulated yeast has been developed to determine characterization of encapsulated yeast applied for ethanol production from lignocellulose waste. Encapsulated yeast as biologically activate materials enclosed in a semipermeable membrane to protect cell from inhibitor attack. Encapsulated yeast system relates to mass transfer of substrate (glucose) into capsule and out of capsule and fermentation reaction. Modelling of mass transfer was developed to understand capsule performance consisting of 3 parts, cell aggregate, liquid space and thin membrane. Finite element method has been applied to solve partial differential equation of glucose concentration profile against x, y position and t -time in Comsol multhiphysics 3.5a. Capsule geometry was showed in half part capsule, 2D and axis symmetries. Trend line of glucose distribution was effected by thickness membrane that 0.1 mm controlling in mass transfer and cell aggregate of 50%-v of membrane.Keywords: computational fluid dynamics, encapsulated yeast system, glucose mass transfer
EVOLUTION OF UZBEKISTAN INFORMATION AND LIBRARY SYSTEM IN THE CONTEXT OF HISTORICAL TRANSFORMATIONS
Authors: Tsai I. K. , Artemyeva E. B.
Published: December 2019

The paper describes the library network history in Uzbekistan. It characterizes a number of problems of the republican modern library system.
WORKS BY A. S. PUSHKIN IN SIBERIANS’ READING DURING THE PRE-REVOLUTIONARY AND CONTEMPORARY PERIODS (TO THE 220 ANNIVERSARY SINCE THE BIRTH OF THE POET)
Authors: Timofeeva Yu. V.
Published: December 2019

The number of titles and volumes of works by A. S. Pushkin in city libraries of Siberia during the late imperial period is counted. A. S. Pushkin’s place in the ratings of writers made by the author of the article on a basis of book borrowings in the libraries of Siberian cities at the beginning of the XX century is defined. The demand for works by A. S. Pushkin in Siberians’ reading during the pre-revolutionary period is revealed. The attitude of regional residents towards his works at the end of the XX – the beginning of the XXI century is analyzed.
REORGANIZATION AND MODERNIZATION OF THE PUBLISHING SEGMENT OF THE PRINTING INDUSTRY OF SIBERIA AND THE FAR EAST AT THE BEGINNING OF THE XXI CENTURY
Authors: Troyak I. S.
Published: December 2019

The course of privatization of state-owned printing enterprises in the period of 2008–2017 is presented as well as its consequences in Siberia and the Far East. The characteristic of the most promising areas of modernization and diversification of printing houses in the situation of reduction of total volume of publishing products output is given.
TRANSLATIONS OF RUSSIAN AND FOREIGN WRITERS INTO THE ALTAI LANGUAGE
Authors: Kuleeva R. R.
Published: December 2019

Brief review on the history of translating Russian and foreign classics into the Altai language is given. Altai Republican National Library named after M. V. Chevalkov activity in popularizing literature in the Altai language and increasing reader’s interest to the literature in translation is considered.
Academic Jealousy Scale: Validity and Reliability Study
Authors: KOÇAK Duygu
Published: December 2019

This study
aims to develop a measurement tool to determine the level of academic jealousy.
For this purpose, firstly, the literature was examined, and a theoretical
framework was formed, and then an item set of 47 items was created. The items
that were submitted to expert opinion were eliminated and corrected, and 41
items were decided to use, and a trial form was obtained. In this study, 478
university students were reached. One-on-one interviews were conducted with ten
students who are studying at Alanya Alaaddin Keykubat University before the
trial application. Then, the trial form was applied to 254 university students,
and the data obtained were analyzed with Exploratory Factor Analysis, and as a
result of this analysis, a structure with three factors (maturity,
self-denigration, and envy) was revealed. In order to test the defined
structure, the final form of the scale was applied to another group of 154
people, and the data obtained were subjected to Confirmatory Factor Analysis,
and goodness of fit indices of the scale was found to be between good fit or
acceptable fit. Accordingly, the structure with 19-item and three factors was
confirmed Cronbach Alpha internal consistency coefficient of the whole scale
was found .779, Envy subfactor was found .840; self-denigration subfactor was
found .840 and Maturity subfactor was found .817. In order to determine the
reliability of the scale in terms of stability, the scale was applied to a
different group of 57 people at two-week intervals, and the correlation between
the two applications was recorded as .89. It was concluded that the Academic
Jealousy Scale developed according to these findings, is a valid measurement
tool and will give reliable scores in measuring academic jealousy.
İSLAM İKTİSAT DÜŞÜNCESİNDE YOKSULLUK PROBLEMİ
Authors: KORKUT Ramazan
Published: December 2019

İktisadi açıdan
zenginlik karşısında yoksulluk olgusu genelde dünyanın, özelde İslam dünyasının
ortak sorunlarından biridir. Yoksulluğun birey, toplum ve devlet bazında boyutları
bulunmakta ve çeşitli sorunlara zemin hazırlayabilmektedir. Bu nedenle sebep, sonuç
ve çözüm yöntemleri bakımından ele alınması gereken önemli bir olgudur. İslam iktisadı
esas aldığı dini ve insani değerlerle bu sorunu çözmeyi hedeflemektedir. Zenginliği
yoksulluğa karşı dini/insani bir paylaşım aracına dönüştürmektedir. Maslahat
kapsamında ticarete, tarıma, hayvancılığa, sanayileşmeye, istihdam alanı
oluşturmaya ve emeği esas alarak çalışmaya teşvik etmektedir. Öte yandan özel
mülkiyet ve paylaşım dengesi kurarak sosyal adaleti sağlamaya çalışmaktadır. Yoksulluğa
karşı dini, hukuki ve ahlaki bir bütünlük içinde önlem almaktadır. İnsanı,
insan onurunu ve toplumu yoksulluğun muhtemel zararlarından korumaktadır. Makalemizde
fakirlik/yoksulluk problemi tanım, sebep ve sonuçları bakımından ele alınmakta,
İslam iktisat düşüncesinin yoksulluğa yaklaşımı ve bu sorun karşısında aldığı dini/insani
tedbirler üzerinde durulmaktadır.
Desmoplastic Fibroma in the Distal Humerus of a 14-Year-Old Boy
Authors: Boyd Jason , Jonard Brandon , Weiner Scott
Published: December 2019

Case:

We present the case of a 14-year-old male who presented with a pathologic elbow fracture. Imaging demonstrated a lytic distal humerus metaphyseal lesion with a soap bubble appearance. After fracture healing, frozen sections obtained at open biopsy suggested fibrous tissue; thus, curettage and bone grafting was performed. Pathology confirmed desmoplastic fibroma. The patient experienced a recurrence 18 months later and had repeat curettage and allograft strutting. He had no evidence of re-recurrence 2 years after the second surgery.

Conclusions:

Desmoplastic fibroma may mimic the presentation of many bone lesions. Recurrence is common despite curettage and bone grafting. This patient performed well without wide resection.
Surgical Treatment for Congenital Dislocation of the Patella in a Young Adult
Authors: Maia Rosa João , Carvalho André Dias , Coutinho Luís Lopes , Esteves João , Pereira Paulo , Vilaça Adélio
Published: December 2019

Case:

We present an 18-year-old man with poor alignment of the lower limbs, marked by congenital dislocation of the left patella, with gait impairment, and an associated 20° flexion contracture. Surgical treatment was performed with a single complex procedure with the release of the lateral retinaculum, capsule, and iliotibial tract, followed by a subtraction trochleoplasty, tibial tubercle transfer, elongation of the quadriceps tendon, and anatomical reconstruction of the medial patellofemoral ligament. At the 5-year follow-up, the patient had a significant improvement in gait pattern, with the patella centered on the new trochlear groove without any signs of patellar instability.

Conclusions:

The approach of congenital dislocation of the patella is controversial, and although numerous procedures have been described in children, the approach in adults should be individually tailored. In this case, trochlear deepening and preserving the trochlear cartilage proved to be an effective option for treating a congenital dislocation.
The role of Airbnb creating a “new”-old city centre: facts, problems and controversies in Porto
Authors: Chamusca Pedro , Rio Fernandes José , Carvalho Luís , Mendes Thiago
Published: December 2019

Urban tourism growth, favoured by short term rental platforms like Airbnb, is changing the cities dramatically. All over Europe local governments have been facing unbridled growth of the so-called sharing economy and developed different regulatory approaches: full prohibition; laissez-faire; and different sorts of limitations. We take Porto as a case-study, considering the exponential growth of tourism, Airbnb and floating city users over the past decade. We make use of qualitative and quantitative methods and draw on the official AirDNA database to analyse the relation between Airbnb and urban transformation, and the governance context. We conclude that the growth of floating city-users –stimulated by Airbnb– has been the main driver of urban change. The case of Porto –which in many ways illustrates the fast growth of short-term, rental-driven urban tourism in southern Europe– demonstrates that Airbnb’s global corporate narrative around property sharing, micro-entrepreneurship and tourism democratization hardly fits the urban reality of host professionalization, income concentration and growing massification. In this context, besides laissez-faire, urban sustainability concerns call for smarter regulatory approaches associated with more widely shared visions, and clear short, medium and long-term objectives.
Golden hordes or mere barbarians? Discourses on tourism, touristification, and tourismophobia in Madrid’s Lavapiés neighborhood
Authors: Barrado-Timón Diego Antonio , Hidalgo-Giralt Carmen
Published: December 2019

¿Hordas doradas o simplemente bárbaros? Los discursos sobre el turismo, la turistificación y la turismofobia en el barrio de Lavapiés (Madrid)El barrio de Lavapiés, como el conjunto de la ciudad de Madrid, está experimentado en los últimos años un explosivo crecimiento turístico. En este contexto, están empezando a aparecer en la prensa discursos críticos con el proceso, y, sobre todo, con el modelo de desarrollo basado en nuevas formas de alojamiento y en el uso de tecnologías que ponen directamente en contacto a oferentes y consumidores. Frente a estos, encontramos otras narrativas que defienden dicho modelo, y que apuestan por su desarrollo. La investigación se plantea si dichas construcciones discursivas están compitiendo por la hegemonía, y, en consecuencia, por su capacidad para configurar los escenarios de futuro e influir en la configuración social y geográfica del barrio. Con el fin de responder a esta pregunta se ha optado por una metodología de análisis del discurso mixta, que incluye métodos cuantitativos (Lingüística de Corpus) y cualitativos (Análisis Crítico del Discurso). Las conclusiones son que, aun cuando incipiente, la competencia discursiva por redefinir los términos del debate en torno al turismo existe en Lavapiés; y aun cuando limitado, dicho debate está teniendo a su vez un impacto en la imagen percibida y en la realidad de este espacio del centro de Madrid.
El Madrid vivido: los problemas urbanos desde la perspectiva de la ciudadanía en el contexto del turismo de masas
Authors: Ruano de la Fuente José Manuel , Iglesias Jiménez Eduardo , Polo Villar César
Published: December 2019

El artículo analiza los problemas del distrito Centro de Madrid desde la perspectiva de sus habitantes. Partiendo de la presentación de las principales características demográficas y territoriales del distrito y del análisis de los instrumentos de intervención impulsados desde el Ayuntamiento, se identifican posteriormente los principales problemas sentidos por la población a partir de los datos contenidos en los espacios formales de participación ciudadana y de las entrevistas mantenidas con representantes de asociaciones de vecinos, técnicos municipales, concejales e individuos no organizados. El trabajo muestra, desde la perspectiva de los ciudadanos, que el turismo no es percibido como uno de los principales problemas del distrito Centro, aunque sí lo son otros fenómenos asociados a él.
Turistificación de centros urbanos: clarificando el debate
Authors: De la Calle Vaquero Manuel
Published: December 2019

Las ciudades son destinos turísticos de extraordinario dinamismo. Visitantes y actividades turísticas se concentran en los centros urbanos, sometidos a intensos procesos de turistificación. A partir de revisión bibliográfica, se aborda un estudio de estos procesos atendiendo a sus causas, manifestaciones y efectos sobre la ciudad. El objetivo central del artículo es ayudar a clarificar un debate que ha transcendido el ámbito académico para convertirse en un componente destacado de la agenda urbana contemporánea. A nivel de estado de la cuestión, se identifican puntos de continuidad y de innovación en los estudios sobre el impacto del turismo en la ciudad. Respecto a la naturaleza del fenómeno, se diferencia entre manifestaciones que sólo implican una intensificación de problemas previos y cambios recientes de alcance disruptivo, caso de la proliferación de las viviendas de uso turístico.
Conflicts in the tourist city from the perspective of local social movements
Authors: Romero-Padilla Yolanda , Cerezo-Medina Alfonso , Navarro-Jurado Enrique , Romero-Martínez José María , Guevara-Plaza Antonio
Published: December 2019

Conflictos en la ciudad turística desde la perspectiva de los movimientos sociales localesEsta investigación aborda los conflictos generados por el crecimiento turístico reciente en la ciudad turística desde la perspectiva de los movimientos sociales locales. Para ello primero, se revisan estos procesos de crecimiento, con especial atención a la percepción del exceso de turismo y al papel de las viviendas con fines turísticos. En segundo lugar, se reflexiona sobre los conflictos y las reacciones sociales que responden a la percepción de impactos negativos del turismo en su espacio cotidiano. Se contrasta la revisión teórica de manera aplicada a las ciudades de Málaga y Marbella. Los resultados evidencian que en las ciudades con turismo clásico de litoral ya existía la vivienda de alquiler desde sus orígenes como destino y ahora se ha visibilizado porque las plataformas digitales lo han puesto en el mercado global; en ciudades con turismo urbano-cultural las viviendas son una nueva forma de alojamiento que genera nuevos conflictos; por último, los resultados contrastan las características del modelo crecentista en la ciudad turística frente a las reivindicaciones de los movimientos sociales que cuya base es la compatibilidad del turismo con la preservación y mejora de la calidad de la vida cotidiana. Los tres resultados constituyen oportunidades de investigación.
Identification of novel alternative splicing isoform biomarkers and their association with overall survival in colorectal cancer
Authors: Lian Haifeng , Wang Aili , Shen Yuanyuan , Wang Qian , Zhou Zhenru , Zhang Ranran , Li Kun , Liu Chengxia , Jia Hongtao
Published: December 2019

Alternative splicing is an important mechanism of regulating eukaryotic gene expression. Understanding the most common alternative splicing events in colorectal cancer (CRC) will help developing diagnostic, prognostic or therapeutic tools in CRC. Publicly available RNA-seq data of 31 pairs of CRC and normal tissues and 18 pairs of metastatic and normal tissues were used to identify alternative splicing events using PSI and DEXSeq methods. The highly significant splicing events were used to search a database of The Cancer Genome Atlas (TCGA). We identified alternative splicing events in 10 genes marking the signature of CRC (more inclusion of CLK1-E4, COL6A3-E6, CD44v8-10, alternative first exon regulation of ARHGEF9, CHEK1, HKDC1 and HNF4A) or metastasis (decrease of SERPINA1-E1a, CALD-E5b, E6 and FBLN2-E9). Except for CHEK1, all other 9 splicing events were confirmed by TCGA data with 382 CRC tumors and 52 normal controls. Two splicing events (COL6A3 and HKDC1) were found to be significantly associated with patient overall survival. The alternative splicing signatures of the 10 genes are highly consistent with previous reports and/or relevant to cancer biology. The significant association of higher expression of the COL6A3 E5-E6 junction and HKDC1 E1-E2 with better overall survival was firstly reported. This study might be of significant value in the future biomarker, prognosis marker and therapeutics development of CRC.
Maternal and partner’s level of satisfaction on the delivery room service in University of Gondar Referral Hospital, Northwest, Ethiopia: A comparative cross-sectional study.
Authors: Taddese Asefa Adimasu , Gashaye Kiros Terefe , Dagne Henok , Andualem Zewudu
Published: December 2019

Background: Asking patients/clients what they perceive about the care and treatment they have received is one of the important steps towards improving the quality of health care. In the scientific world, a number of efforts have been tried to understand about what laboring mothers perceive about the care provided. However, little is known about the birth experiences of partners in Ethiopia. Therefore, this study was aimed to assess the maternal and partner’s level of satisfaction on the delivery room service in the study area.
Methods: A comparative cross-sectional study was conducted from Dec 2018 to January 2019 in University of Gondar referral hospital. The birth satisfaction scale is used for the mother, and it was adapted to the partners’ perspective. Paired-samples t tests were used for comparing mothers and partners for the birth satisfaction scales global and thematic scores. A binary logistic regression model was fitted to identify predicting factors for mothers’ and partners satisfaction.
Results: The overall satisfaction of mothers in this study was 47.6 % whereas 41.2% of partners were satisfied by delivery room services. There were mean difference between mothers and partners’ birth satisfaction scale (p=0.02). Maternal satisfaction scale was affected by age [OR = 0.36, 95%CI (0.18, 0.73 )], perception [OR =0.02, 95%CI (0.001,0.09)], waiting time [OR = 0.11 , 95%CI (0.001, 0.09)],visiting mode [OR = 0.01 , 95%CI (0.001,0.08)], pregnancy status [OR = 0.04, 95%CI (0.01 ,0.33)] and fatal outcome [OR=0.001, 95%CI (0.001,0.018)] .whereas, partners satisfaction was associated with age [OR=0.16,95%CI (0.05 0.49)], occupational status [OR = 0.02, 95%CI (0.001, 0.24), amount of money to pay for service [OR = 2.87, 95%CI (1.07, 7.71), visiting mode of his wife [OR = 0.08, 95%CI (0.01, 0.35)], waiting time [OR = 0.12, 95%CI (0.04, 0.33)], privacy [OR = 10.61, 95%CI (3.00, 37.52)], mode of delivery of his wife [OR = 7.69, 95%CI (3.00, 19.69)].
Conclusion : This finding would alert the health care system to design a client-friendly approach. It will provide insight to hospital administrators and providers in formulating a policy that would enhance the support of partners during labour and delivery process.
MEG3 promotes proliferation and inhibits apoptosis in osteoarthritis chondrocytes by miR-361-5p/FOXO1 axis
Authors: Wang Anying , Hu Naixia , Zhang Yefeng , Chen Yuanzhen , Su Changhui , Lv Yao , Shen Yong
Published: December 2019

Background: This study aimed to investigate the role of long non-coding RNA (lncRNA) maternally expressed 3 (MEG3) and related molecular mechanisms in osteoarthritis (OA).
Methods: Patients with OA and patients undergoing thigh amputation were enrolled in OA group and normal group, respectively. Cartilage tissues of all patients were isolated and cultured. After different transfections, chondrocytes were classified into Blank, pcDNA3.1-NC, pcDNA3.1-MEG3, si-NC, si-MEG3, pcDNA3.1-NC + mimics NC, pcDNA3.1-MEG3 + mimics NC, pcDNA3.1-NC + miR-361-5p mimics and pcDNA3.1-MEG3 + miR-361-5p mimics groups. The qRT-PCR was used to detect the expression of MEG3, miR-361-5p and FOXO1. Western blot, luciferase reporter assay, RIP, CCK-8 and flow cytometry analysis were performed to reveal the morphology, proliferation and apoptosis of cartilage cells. Histological analysis and immunostaining were conducted in OA rat model.
Results: The expression of MEG3 and FOXO1 in OA was significantly decreased while miR-361-5p was increased compared with the normal group. MEG3 might serve as a ceRNA of miR-361-5p in OA chondrocytes. Moreover, the western blot and CCK-8 assay showed that MEG3, targeted miR-361-5p/FOXO1, might elevate cell proliferation and impair cell apoptosis. Functional analysis in vivo showed that MEG3 suppressed the cartilage matrix degradation.
Conclusion: Taken together, MEG3 can contribute to cell proliferation, inhibit cell apoptosis and extracellular matrix (ECM) degradation via miR-361-5p/FOXO1 axis in OA chondrocytes.
The Cost-effectiveness of screening tools used in the diagnosis of fetal alcohol spectrum disorder: A modeled analysis
Authors: Berrigan Patrick , Andrew Gail , Reynolds James N , Zwicker Jennifer D
Published: December 2019

Background Fetal Alcohol Spectrum Disorder (FASD) is characterized by physical and neurological abnormalities resulting from prenatal alcohol exposure. Though diagnosis may help improve patient outcomes, the diagnostic process can be costly. Subsequently, screening children suspected of FASD prior to diagnostic testing has been suggested, to avoid administering testing to children who are unlikely to receive a diagnosis. The present study set out to assess the cost-effectiveness of currently recommended FASD screening tools. Methods The screenings tools evaluated were chosen from Children’s Healthcare Canada’s National Screening Toolkit for Children and Youth Identified and Potentially Affected by FASD and include meconium testing of fatty acid ethyl esters (meconium testing) and the neurobehavioral screening tool (NST). An economic model was constructed to assess cost-effectiveness. One-way and probabilistic sensitivity analyses were conducted to assess the robustness of findings. Costs reflect 2017 Canadian dollars and the perspective is the public healthcare system. Results Both screening tools evaluated resulted in reduced costs and fewer diagnosed years of life than a no screening strategy in which all children suspected of FASD receive diagnostic testing. The model predicts that screening newborns with meconium testing results in a reduced cost of $89,186 per 100 individuals screened and 38 fewer diagnosed years of life by age 18, corresponding to an incremental cost-effectiveness ratio (ICER) of $2,359. Screening children with the NST resulted in a reduced cost of $183,895 per 100 individuals screened and 77 fewer diagnosed years of life by age 18, corresponding to an ICER of $2,390. Conclusion Findings suggest that screening is associated with less use of healthcare recourses but also fewer years of life with an FASD diagnosis over a no screening strategy. Since diagnosis can be key to children receiving timely and appropriate health and educational services, cost-savings must be weighed against the fewer years of life with a diagnosis associated with screening.
Shortening Antibiotic Duration in the Treatment of Acute Cholangitis. Rationale and Study Protocol for an Open Label Randomized Controlled Trial.
Authors: Iwata Kentaro , Doi Asako , Oba Yuichiro , Matsuo Hiroo , Ebisawa Kei , Nagata Manabu , Nishimura Sho , Yoshimura Kenichi , Masuda Atsuhiro , Shiomi Hideyuki , Kodama Yuzo
Published: December 2019

Background: Antimicrobial therapy with appropriate biliary drainage is considered the standard of care for acute cholangitis, but the optimal duration of antimicrobial therapy remains unknown. Seven to 10 days of antimicrobial therapy is common for the treatment of acute cholangitis, but a recent retrospective cohort study suggested a shorter duration might be effective . A shorter duration of antimicrobial therapy can be beneficial in decreasing the length of hospital stay, improving patients’ quality of life, decreasing adverse effects, and even contributing to a decrease in the occurrence of antimicrobial resistance. Methods/design: We will conduct a multi-center, open-label, randomized, non-inferiority trial to compare short course therapy (SCT) with conventional long course therapy (LCT) in treating patients with acute cholangitis. SCT consists of 5-day intravenous antimicrobial therapy if the patients had clinical improvement, while at least 7 days of intravenous antibiotics will be provided to the LCT group. The primary outcome is clinical cure at 30 days after onset. Patients will be randomly assigned in an open label fashion. A total sample size of 150 was estimated to provide a power of 80% with a one-sided alpha level of 2.5% and a non-inferiority margin of 10%. Discussion: This trial is expected to reveal whether SCT is non-inferior to conventional LCT or not, and may provide evidence that one can shorten the treatment duration for acute cholangitis for the benefit of patients.
The Impact of HIV Knowledge and Attitudes on HIV Testing Acceptance among Patients in an Emergency Department in the Eastern Cape, South Africa
Authors: Ryan Sofia , Hahn Elizabeth , Rao Aditi , Mwinnyaa George , Black John , Maharaj Roshen , Mvandaba Nomzamo , Nyanisa Yandisa , Quinn Thomas C. , Hansoti Bhakti
Published: December 2019

Background: Transmission of HIV in South Africa continues to be high due to a large proportion of individuals living with undiagnosed HIV. Uptake of HIV testing is influenced by a multitude of factors including the patient’s knowledge and beliefs about HIV. Methods: This study sought to quantify the impact of knowledge and attitudes on HIV testing acceptance in an emergency department by co-administering a validated HIV knowledge and attitudes survey to patients who were subsequently offered HIV testing. Results: During the study period 223 patients were interviewed and offered HIV testing. Individuals reporting more negative overall attitudes (p = 0.006), higher levels of stigma to HIV testing (p<0.001), and individuals who believed their test was confidential (p<0.001) were more likely to accept an HIV test. Conclusions: Interventions focused on improving patient perceptions around testing confidentiality will likely have the greatest impact on testing acceptance in the emergency department.