bluuebunny/crossref_metadata_2025 huggingface dataset:
Accelerated COVID-19 vaccination for Sri Lankans
Authors: Adikari Pamila Sadeeka , Pathirathna K.G.R.V.
Published: October 2022

No Abstract available.
Perioperative hemodynamic protective assessment of adaptive support ventilation usage in pediatric surgical patients
Authors: Dmytriiev Dmytro , Melnychenko Mykola , Dobrovanov Oleksandr , Nazarchuk Oleksandr , Vidiscak Marian
Published: October 2022

Background: The aim of this study was to evaluate the hemodynamic protective effects of perioperative ventilation in pressure-controlled ventilation (PCV) and adaptive support ventilation (ASV) modes based on non-invasive hemodynamic monitoring indicators.Methods: The study included 32 patients who were scheduled for planned open abdominal surgery. Depending on the chosen ventilation strategy, patients were included in two groups of PCV mode ventilation (n=14) and ASV mode ventilation (n=18). The hemodynamic effects of the ventilation strategies were assessed by estimated continuous cardiac output (esCCO) and cardiac index (esCCI). Results: Preoperative cardiac output (CO) was 6.1±1.3 L/min in group 1 patients and 6.3±0.8 L/min in group 2 patients, and preoperative cardiac index (CI) was 3.9±0.4 mL/m2 in group 1 patients and 3.8±0.8 mL/m2 in group 2 patients. The ejection fraction (EF) in group 1 subjects was 55.4%±0.3%; this rate was 56.5%±0.5% in group 2 subjects. Group 1 patients experienced a 14.7% CO decrease to 5.2±0.7 L/min, a 17.9% CI decrease to 3.2±0.6 mL/m2, and a 12.8% mean arterial pressure decrease to 82.3±9.4 mm Hg 30 minutes after the start of surgery. One hour after the start of surgery, the CO mean values of group 2 patients were lower than baseline by 7.9% and differed from the dynamics of patients in group 1, in whom CO was lower than baseline by 13.1%. At the end of the operation, the CO values were lower than baseline by 11.5% and 6.3% in patients of groups 1 and 2, respectively. Our data showed that the changes in EF during and after surgery correlated with CO indicators determined by the esCCO.Conclusions: In our study, perioperative ventilation in ASV mode was more protective than PCV mode and was characterized by lower tidal volume (16.2%) and driving pressure (ΔP) (12.1%). Hemodynamically-controlled mechanical ventilation reduces the negative impact of cardiopulmonary interactions.
Radikalne prakse izobraževanja odraslih v zasedenem hotelu City Plaza
Authors: Lihtenvalner Katja
Published: October 2022

Članek izhaja iz političnega, družbenega in gospodarskega konteksta Grčije, v kateri so se od leta 2016 po sporazumu med EU in Turčijo znašli novoprispeli begunci in migranti. Prisilno marginalizirani novoprišleki so se znašli ujeti v tradicionalno sovražnem migracijskem okolju. Grčija se je že spopadala s hudimi neoliberalnimi politikami, ki so jih vsilili tuji posojilodajalci in so jih sprejele domače politične elite ter so drastično prizadele državo blaginje. V politično in gospodarsko razburkanih časih sta institucionalni rasizem in socialna izključenost postala del nacionalnih migracijskih politik. Z izvedbo kvalitativnih intervjujev, opazovanjem z udeležbo in preučevanjem sekundarnih virov članek raziskuje stanovanjski urbani projekt, ki se je razvil kot odgovor na neoliberalne hegemonske politike. Ugotovitve kažejo, da so izobraževalne pobude vodile k izgradnji protihegemonske skupnosti, ponudile prakse solidarnosti in kolektivnega učenja ter pomagale pri izobraževanju splošne javnosti.
»Čigavi študenti smo, če ne vaši«
Authors: Radilovič Hana , Brezar Borut
Published: October 2022

Avtorja pojasnjujeta, kako se v slovenskem univerzitetnem prostoru v zvezi s »tujimi« študenti v zadnjem desetletju pojavljajo predsodki, diskriminatorne politične poteze in poskusi njihove legitimacije. V dogajanje sta se vključila prek Gibanja za dostojno delo in socialno družbo. Svoj pristop opredeljujeta v okviru metode participatornega akcijskega raziskovanja. Tako na področju visokega šolstva kot razmerja med delom in kapitalom se kot vztrajni ideološki potezi, ki spremljata ukrepe za krepitev razredne moči kapitala, izkazujeta neokonservatizem (posebej nacionalizem) in neoliberalizem. V študentskem in delavskem gibanju se zato v znamenje odpora proti njima gradijo solidarnostne vezi onkraj narodne pripadnosti, pri čemer je ključnega pomena radikalno izobraževanje navznoter in navzven.
Enhanced Degradation of Sulfamethoxazole Using Immobilized Biomass Reactor
Authors: Duc Ha Danh
Published: October 2022

Sulfamethoxazole (SMX) is a common antibiotic frequently detected in the environment. This study investigated enhanced substrate degradation using an immobilized biomass reactor. The degradation rates increased in the batch reactor operation, owing to the increased biomass of immobilized microorganisms in polyurethane foam (PUF). The degradation rate at 50 mg/L was 38.8±3.8 mg SMX/day, and immobilized microorganisms achieved 406.6±42.2 mg dry biomass/g dry PUF under optimum conditions. Two SMX-degrading bacterial strains, Acinetobacter sp. S1 and Pseudomonas sp. S2, were isolated from the immobilized biomass. Furthermore, this study analyzed the possible SMX degradation pathway based on the intermediates of each isolate. The cooperation of these isolated strains resulted in increased degradation and reduced produced metabolites. The degradation by the immobilized cells of the mixed isolated bacteria in continuous operation exceeded 93% SMX at the hydraulic retention time of 36 h at 50 mg/L.
Employer attractiveness of family businesses in the it-industry: the effect of personality traits and the moderating role of ownership communication
Authors: Spieß Teresa , Nickel Valerie , Faißt Rebekka , Zehrer Anita
Published: October 2022

Purpose - Employing a qualified workforce is a crucial topic for organization-al success. Research on employer branding in family businesses has not come to a clear conclusion of which family business characteristics might be attractive for which potential employees. Aim(s) - This paper focuses on family businesses in the IT industry to ana-lyze whether they might or might not profit from the communication of family involvement. Design/methodology/approach - To answer the research question, an online survey was conducted. The participants were divided into two groups, whereby one group was manipulated by the communication of the ownership. Findings - The results show that family businesses are associated with greater security but fewer development opportunities. In addition, certain personality traits of job applicants influence the perception of organizational attractiveness. However, the communication of ownership had no signifi-cant influence on employer attractiveness. Similarly, the varying importance of job security and development opportunities among applicants cannot be clearly explained by personality traits. Limitation of the Study - The final sample size was relatively small. In addi-tion, in reality the applicants would be provided with more and more de-tailed information about the company. The representativeness and general-izability of the survey must therefore be questioned. Practical implications – As the results show a positive correlation between perceived job security, opportunities for further development and attrac-tiveness, it might be valuable for family businesses to support and com-municate job security and opportunities for further development for raising increased attractiveness. Originality/value - The attempt is made to give companies, especially family businesses, a better understanding of the effect of communicating the ownership relationship on potential applicants.
Self-compassion, employee burnout and performance: serial mediation by free time management and flow experience
Authors: Arı Ela , Erdoğan Ecem
Published: October 2022

Purpose - In the last decade, researchers have shown growing interest in finding the variables related to employee burnout and performance. Recent studies have shown that various positive psychological concepts, particularly flow experience and self-compassion, have positive effects on employee burnout and performance. Aims - This study aims to investigate the role of self-compassion on burn-out and performance through free time management and flow experience at work. Design/Methodology - Using a comprehensive model with a cross-sectional design, a survey study was constructed with a sample of 214 em-ployees, collected from both public and private industry employees. SPSS v24 was used to test the serial mediator’s model. Findings: The results demonstrated that self-compassion reduce burnout and enhance performance and these relationships are mediated serially by free time management and flow experience. Limitations of the study - This study used self-report instruments with a cross sectional design. Future studies are suggested to use experience-sampling method to avoid common method bias and to measure instant flow experience. Practical implications - Practices that increase self-compassion, free time management and flow activities can be beneficial to enhance job perfor-mance while reducing burnout. Moreover, encouraging self-growth, auton-omy, and feedback can foster flow state at work. Originality/value - Less attention was given to free time management and this study provided support for the importance of administering employee’s time outside the work.
Tình hình kết quả sinh non tại Bệnh viện Trung ương Thái Nguyên năm 2020
Authors: Nguyễn Thị Hồng , Lục Thị Xuân , Nguyễn Thị Giang , Bế Thị Hoa , Cao Thị Quỳnh Anh , Hoàng Quốc Huy
Published: October 2022

Mục tiêu: Mô tả đặc điểm lâm sàng, cận lâm sàng và nhận xét diễn biến tình trạng trẻ sơ sinh non tháng ở sản phụ sinh non tại Khoa Sản Bệnh viện Trung ương Thái Nguyên.

Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang 123 sản phụ sinh non tại Khoa Sản Bệnh viện Trung ương Thái Nguyên từ tháng 1 đến tháng 12 năm 2020.

Kết quả và kết luận: Nhóm tuổi 20 - 35 chiếm tỉ lệ cao nhất 84,6%. Sản phụ sống ở nông thôn chiếm 55,3%. Tuổi thai 34 - < 37 tuần chiếm tỷ lệ cao nhất 62,2%. Có 19,5% trường hợp thiểu ối. Tỷ lệ sản phụ có thiếu máu chiếm 16,3%. Trong số 123 trẻ non tháng sinh ra có 56 trẻ nằm cùng mẹ, 67 trẻ chuyển khoa nhi điều trị, 6 trẻ tử vong sau sinh.Trẻ có trọng lượng sơ sinh từ 1500 - 2499gr chiếm tỷ lệ cao nhất 53,7%. Trong tổng số 67 trẻ chuyển nhi điều trị, suy hô hấp chiếm 35,8%, vàng da chiếm 9,0%. Trẻ mắc kết hợp từ hai bệnh trở lên chiếm tỷ lệ 55,2%
Tình hình phẫu thuật cắt tử cung cấp cứu sau sinh đường âm đạo tại Bệnh viện Phụ sản Trung ương trong 5 năm (2017 - 2021)
Authors: Đoàn Thị Phương Lam , Ngô Minh Thắng , Nguyễn Mạnh Thắng
Published: October 2022

Mục tiêu: Xác định tỷ lệ phẫu thuật cắt tử cung cấp cứu sau sinh đường âm đạo và tìm hiểu các yếu tố nguy cơ dẫn đến phẫu thuật cấp cứu.

Đối tượng và Phương pháp nghiên cứu: Phân tích hồi cứu qua hồ sơ bệnh án tất cả những trường hợp phẫu thuật cắt tử cung cấp cứu sau sinh đường âm đạo tại Bệnh viện Phụ sản Trung ương từ năm 2017 đến hết năm 2021.

Kết quả: Có 6/49.445 ca đẻ đường âm đạo phải phẫu thuật cắt tử cung cấp cứu sau sinh tại Bệnh viện Phụ sản Trung ương trong 5 năm. Tỷ lệ chung của phẫu thuật cấp cứu sau đẻ đường âm đạo là 0,12 cho mỗi 1000 ca đẻ tính từ năm 2017 đến năm 2021. Trong số ca cắt tử cung cấp cứu sau đẻ có năm ca là đẻ thường, một ca sau đẻ thủ thuật Forceps. Chỉ định cắt tử cung cấp cứu đứng đầu là do đờ tử cung với 3 ca (50%), tiếp đến là bất thường rau thai có 2 ca (33,3%), tổn thương đoạn dưới tử cung là 1 ca (16,7%). Trong 6 ca mổ cắt tử cung thì có 5 ca sinh con từ lần thứ 3 trở lên chiếm tỷ lệ cao nhất 83,3%, 1 ca sinh con lần hai (16,7%), không có ca nào sinh con lần đầu.

Kết luận: Với những trường hợp sinh con từ lần thứ 3 trở lên hoặc trong quá trình khám thai và siêu âm nghi ngờ rau thai bám bất thường (phù thai rau, nghi ngờ rau cài răng lược một phần, hoặc mổ đẻ cũ) thường có nguy cơ chảy máu nặng do đờ tử cung sau đẻ hoặc rau không bong dẫn đến phải cắt tử cung cấp cứu sau sinh. Vì vậy, với những trường hợp này nên khuyên sản phụ đến đẻ tại những cơ sở sản khoa có bác sĩ sản khoa có kinh nghiệm và có khả năng phẫu thuật tốt để cuộc chuyển dạ đẻ đạt kết quả tối ưu nhất, tránh được những tai biến nặng cho sản phụ trong và sau đẻ.
Khảo sát tình trạng sức khỏe mẹ và con ở hai nhóm sinh ngã âm đạo và mổ lấy thai tại tỉnh Cà Mau năm 2021
Authors: Nguyễn Thể Tần , Huỳnh Ngọc Linh
Published: October 2022

Đặt vấn đề: Nhiều nghiên cứu trên thế giới và Việt Nam cho thấy tỉ lệ mổ lấy thai ngày càng tăng. Tình trạng này có thể ảnh hưởng đến sức khỏe mẹ và con về sau.

Mục tiêu nghiên cứu: Đánh giá tình trạng sức khỏe của mẹ và con giữa 2 nhóm sinh ngã âm đạo và sinh mổ sau 2 - 5 năm.

Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang trên 840 bà mẹ và con tại tỉnh Cà Mau năm 2021.

Kết quả: Một số tình trạng của mẹ ở nhóm sinh mổ đều lớn hơn nhóm sinh ngã âm đạo như: thiếu sữa mẹ trong 6 tháng đầu: 59,06% so với 40,95%; thời gian cai sữa dưới 12 tháng: 36,72% so với 28,38%; đau lưng: 38,21% so với 22,2%; sẩy thai: 24,07% so với 16,93%; mổ lấy thai trong lần mang thai sau: 91,14% so với 39,33%; kinh nguyệt không đều: 24,07% so với 15,79%; đau bụng khi hành kinh: 30,52% so với 20,36%; với p < 0,05. Đối với con so sánh ở hai nhóm sinh mổ và sinh ngã âm đạo, tình trạng béo phì: 22,58% so với 14,42%; khò khè: 40,69% so với 28,6%; dị ứng da: 22,08% so với 13,27%; khám bệnh nhiều lần: 38,46% so với 22,2%; số lần nhập viện nhiều: 20,84% so với 13,04%; p < 0,01.

Kết luận: Tỉ lệ thiếu sữa trong 6 tháng đầu, đau lưng, rối loạn kinh nguyệt, sảy thai, mổ lấy thai khi mang thai lần sau…ở nhóm sinh mổ cao hơn nhóm sinh ngã âm đạo. Con của bà mẹ sinh mổ dễ bị thừa cân béo phì, dị ứng da, khò khè, khám bệnh và nhập viện nhiều hơn nhóm bà mẹ sinh ngã âm đạo.
Một số yếu tố liên quan đến kết quả chăm sóc trẻ được điều trị surfactant tại Trung tâm Sơ sinh Bệnh viện Phụ sản Trung ương năm 2020 - 2021
Authors: Ngô Hồng Vân , Lê Minh Trác , Dương Lan Dung
Published: October 2022

Mục tiêu: Phân tích một số yếu tố liên quan đến kết quả chăm sóc trẻ sơ sinh non suy hô hấp được điều trị surfactant tại Trung tâm Chăm sóc và Điều trị Sơ sinh Bệnh viện Phụ sản Trung ương năm 2020 - 2021.

Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang trên 200 trẻ sơ sinh non dưới 37 tuần suy hô hấp được điều trị surfactant tại Trung tâm Chăm sóc và Điều trị Sơ sinh - Bệnh viện Phụ sản Trung ương trong thời gian nghiên cứu từ tháng 11/2020 đến tháng 06/2021. Số liệu được quản lý bằng phần mềm Epidata 3.1 và được phân tích bằng phần mềm Stata 15.

Kết quả: Chăm sóc tốt chiếm 80,5% và chưa tốt là 19,5%, biến chứng xuất huyết phổi chiếm tỷ lệ cao nhất 12%, tuổi thai từ 32 - < 37 tuần chăm sóc tốt gấp 4,54 lần so với nhóm < 32 tuổi, cân nặng từ 1000 g đến dưới < 2500 g chăm sóc tốt gấp 10,13 lần so với nhóm < 1000 g, Silverman 4 - 6 điểm chăm sóc tốt gấp 1,31 lần so với nhóm > 6 điểm, nhóm trẻ không có biến chứng chăm sóc tốt hơn 4 - 6 lần nhóm có biến chứng, các đặc điểm của mẹ ảnh hưởng nhiều đến kết quả chăm sóc trẻ (p < 0,05).

Kết luận: Những yếu tố liên quan đến kết quả chăm sóc có ý nghĩa thống kê bao gồm: tuổi thai, cân nặng, chỉ số Silverman, biến chứng và một số đặc điểm của người mẹ.
Reguladores vegetales y su acción sobre la agronomía en el cultivo de arándano (vaccinium corymbosum L.) en Ica – Perú
Authors: Magallanes Jorge Luis Magallanes , Quijandria Félix Guillermo Fuentes , Donayre Jesús Cavero
Published: October 2022

El cultivo de arándano en los últimos años es uno de los más importante en la región de Ica. El propósito fue determinar el efecto de los reguladores vegetales en el rendimiento y calidad de fruta. El diseño adoptado fue en bloques completamente randomizado con 12 tratamientos más 1 testigo y 4 repeticiones. El mayor rendimiento de arándanos lo obtuvo el tratamiento con la clave 4 Biozyme TF a la dosis del 0.10 % obteniendo un rendimiento total de 3,900 kg/ha, una relación beneficio/costo de 2.86 por cada sol invertido superando al control.
Relasi Perwakilan, Pemilihan dan Voting dalam Penyelenggaraan Demokrasi di Indonesia
Authors: Sumardi Sumardi , Purnomo Eko Prio
Published: October 2022

This paper aims to analyze the practice of political administration in Indonesia with various models and democratic systems that are applied. Using descriptive qualitative analysis with literature review. Through comparison of Model Selection, Representative and Voting. Democracy held through election celebrations general periodicity actually becomes the foundation and umbrella for its creation development of culture and improvement of community welfare and interests general. However, the process tends to indicate that it is just a place to find form and very difficult to adjust. Between Representatives, Elections and Voting exist ideal democracy seems to be an anomaly in the realization of the quality of democracy. The implications are diverse, political parties thrive not in direct proportion to the quality of state policies, strengthening the existence of elite power without caring for common sense government administrators as state control. Finally comes the distribution of power who have no public trust.
Analisis Transformasi Birokrasi Melalui Pengembangan e-Government di Indonesia
Authors: Sumardi  , Nawir Adi , Mukhlis Suardi
Published: October 2022

This paper aims to determine the Analysis of Bureaucratic Transformation through the Development of e-Government in Indonesia. The methodology used in this study uses a library research approach, and data collection is carried out by reviewing and exploring journals, books, and other supporting documents related to the research focus. The results of the study concluded that e-government must be implemented seriously and consistently so that it can support the transparency of public services. Bureaucratic transformation through e-government must be carried out with the support of several factors, namely, regulations, organizational structure, organizational culture, system reconstruction. E-government has the potential to support the transparency of public services through a consistent monitoring system, extensive knowledge of information technology and integrity
Efektivitas Sistem Kearsipan di Badan Kepegawaian dan Diklat Daerah Kabupaten Takalar
Authors: Akhmad Akhmad
Published: October 2022

This paper aims to determine the effectiveness of the filing system implementation at the Education and Training and Regional Personnel Board of Takalar Regency, in addition to knowing the factors that affect the effectiveness of the archive system implementation at the Education and Training and Regional Personnel Agency of Takalar Regency. This study uses a descriptive type of research. The implementation of the archive system at the Office of the Regional Personnel and Education and Training Agency of Takalar Regency has been running effectively. This is supported by the application of a modern archive system and also supported by the quality of Human Resources who are experts in the field of archives and the availability of facilities and infrastructure in the field of archives
Associação genômica ampla para caracteres relacionados à qualidade do grão de milho-pipoca
Authors:   , Gotardi Leonardo Fioravante
Published: October 2022

Os caracteres relacionados a qualidade do grão são de herança poligênica e de estrutura gênica complexa. As alfa-zeinas possuem relação com a capacidade de expansão do grão, enquanto amido, amilose e amilopectina estão relacionados com a textura do grão, desempenhando papel chave na expansão do endosperma translúcido. Foram avaliados 286 genótipos pertencentes a duas populações UFV-MPS e Beija-Flor. O estudo de associação genômica foi conduzido com 140.520 SNPs e 109.999 SNPs, envolvendo 10 e sete caracteres relacionados a qualidade do grão, respectivamente às populações UFV-MPS5 e Beija-Flor. Os resultados demonstraram que existe divergência genética entre as populações para conteúdo de alfa-zeínas (19 e 22 kDa), mas também para concentração de zeínas totais e subunidades de 21 e 27 kDa. Os dados fenotípicos em conjunto com dados genotípicos foram analisados por associação genômica. Para a população UFV-MPS5, foram identificadas 209 associações significativas, sendo 102 referentes a subunidade de 19 kDa, 80 referentes a subunidade de 22 kDa, 8 referentes ao conteúdo de amido e 19 referentes ao conteúdo de amilose. Os genes candidatos para esta população foram relacionados a quatro processos biológicos, um componente celular, quatro funções moleculares e cinco classes de proteinas. Na população Beija Flor foram identificadas seis associações referente a subunidade de 21 kDa. Ao teor de amido e amilose foram identificados quatro genes candidatos, distribuídos em quatro cromossomos (1, 2, 6 e 10). Além destes, foram identificados oito genes candidatos relacionadas as subunidades de zeínas, destes três genes relacionados a biossintese de alfa-zeínas além de fatores de transcrição e chaperonas, demonstrando que o acúmulo e biossintese de zeinas é regido por múltiplos elementos, envolvendo famílias gênicas e fatores transcricionais. Além disso, a utilização da eletroforese micro fluidica, demonstrou-se como ferramenta promissora na caracterização de genótipos em larga escala e na identificação de genótipos de alta CE. Palavras-chave: Milho Pipoca. Alfa-Zeinas. Amido. Amilose. GWAs
Genese de solos aluviais e implicaçoes ambientais no Cariri paraibano
Authors:   , Salgado Renan Figueiredo Silveira
Published: October 2022

A Caatinga é uma das florestas sazonalmente secas com mais biodiversidade do mundo. A região apresenta significativa heterogeneidade fisionômica em decorrência de condições edafoclimáticas como altitude, temperatura, pluviosidade, geomorfologia, relevo, aridez e composição físico-química do solo. A vegetação se destaca pelas formações xerófilas, além de adaptações a estiagens prolongadas e chuvas irregulares, típicas da região. Depósitos aluviais e solos derivados podem ser encontrados em várzeas e terraços aluvionares. A capacidade e competência dos canais fluviais determinam a granulometria do material depositado, bem como o grau de seleção. Alterações nestes parâmetros, ao longo do tempo, favorecem a caracterização de solos aluviais. Registros palinológicos continentais e marinhos no semiárido brasileiro indicam um clima mais úmido e frio do que o atual entre o Holoceno Recente, 6.790 anos antes do presente (AP). A partir da análise da composição química, da textura e da idade dos depósitos sedimentares, poderemos melhor compreender a evolução da paisagem no Cariri Paraibano. Para isto foram utilizadas analises de reatividade do solo, analises sedimentológica da fração areia, geoquímica, cronologia por datação de OSL e Análises de Componentes Principais (PCA). Os solos estudados são Fluvisol, que possuem todas as características necessárias para definição e classificação. Horizontes com semelhanças granulométricas, de teor de MOS e composição química indicam fases deposicionais de larga extensão geográfica. As análises indicam que houve mudanças entre a fase úmida e seca onde se comprova pela análise no tamanho dos grãos de areia. Nos períodos com maior umidade os rios possuíam uma maior carga energética, desta forma sua deposição se baseia em matérias grossos, e nas fases secas onde a carga energética dos rios era enfraquecida os depósitos eram baseados em materiais mais finos e pouco densos. Palavras-chave: Caatinga. Solos. Fluvisol. Depósitos. Sedimentologia.
Vexilología en el electrocardiograma. Signo de la bandera de Sudáfrica
Authors: Estupiñan-Paredes Ruth N. , Robayo-Betancourt Ana M. , Moreno-Ruiz Nelson L.
Published: October 2022

El electrocardiograma (ECG) es un examen que permite tomar decisiones que podrían salvar la vida del paciente. Se debe tener en cuenta que tiene diferentes patrones y diagnósticos diferenciales, como el patrón del síndrome coronario agudo con elevación del segmento ST lateral alto, al cual se denomina el «signo de la bandera de Sudáfrica». Presentamos el caso de un paciente de 44 años que presentó dolor torácico típico en quien se realizó un ECG que evidenció elevación del segmento ST en las derivaciones DI, DII, AVL – V2, e infradesnivel en DIII, lo cual corresponde a una oclusión coronaria aguda con compromiso del segmento lateral del corazón. Este patrón ECG es conocido como el signo de la bandera de Sudáfrica. El pronto reconocimiento permitió la decisión de realizar la terapia farmacológica y la angioplastia de rescate, inmediatamente.
Incisión de Clamshell con esternotomía media como abordaje del aneurisma de arco aórtico complicado
Authors: Polo-Gutiérrez Gerber , Bustinza-Carassa Luis Felipe , Pérez-Valverde Yemmy , Abono Sánchez Yuler
Published: October 2022

Surgical treatment of aortic arch aneurysm is one of the greatest challenges of aortic surgery. We present a young woman with Marfan syndrome, severe Excavated Pectus and previous Bentall procedure, who underwent emergency surgery for ruptured aortic arch aneurysm. We achieved a successful approach through a Clamshell incision associated with a median re-sternotomy.
A Brief Review on Evaluation and Exploration of Antioxidant Activity of Mango Ginger
Authors: Jivaje Kadambari , Inamdar Aparna , Gharge Shankar , Kagwad Pooja , Suryawanshi Shailendra S , Bhandurge Parixit , Palled Mahesh S , Japti Veerakumar
Published: October 2022

Many free radicals are generates in the human body due to metabolic processes and in order to counteract the harmful effects of these antioxidants, human body has a complex system of natural enzymatic and non-enzymatic antioxidant defenses or mechanisms. These free radicals are mainly responsible for generation of different types of diseases and disorders. Hence protection of body against free radical is important and which can also be done by taking diet with maximum antioxidants. Naturally occurring antioxidant are very important in preventing body from various free radicals. Many medicinal plants and their extracts have been reported for potential anti-oxidant activity. Curcuma amada Roxb (Mango Ginger) is the most important genera come under the Zingiberaceae family. Chemically it has reported for the presence of wide range of phytoconstituents which include the flavonoids, terpenoids, tannins steroids, alkaloids, glycosides and essential oils. Due to presence of wide variety of phytoconstituents plant has very well traditional value reported for pharmacological significance for a variety of ailments. It effectively treats skin allergies, stomach problems, and high blood cholesterol and has been reported for antioxidant properties. In the present review work various research articles published on antioxidant activity of Mango Ginger Have been collected from various journal site and databases and explored systematically
Evaluation of wound healing activity of Dhataki Pushpa ointment (Woodfordia fruticosa Kurz.) on Sadyavrana (excised wound) - An experimental study
Authors: Sneha Vidhate R , D S Meena , C Rajkumar , W Nilima , H Shamili
Published: October 2022

Background: Woodfordia fruiticosa Kurz. of Lythraceae is a shrub whose blooms are called Dhataki Kusuma. The fresh flower of W. fruticosa controls bleeding in emergency cuts, whereas the dried flower powder heals wounds faster. Indian tribes utilise it to cure wounds. No scientific evidence supported using W. fruticosa to treat wounds, hence the present study assessed the plant's wound healing ability. Aim: To find out the efficacy of Dhataki Pushpa ointment on Sadyavrana (excised wound). Material & Methodology: BSI (Botanical Survey of India) verified Dhataki flowers. The ointment was prepared and then standardised. This research randomly chose 12 Wistar rats (six for Dhataki Pushpa ointment, and six for betadine). Albino rats (Wistar) of both sexes weighing 150-200 g were used in this research to examine the impact of Dhataki Pushpa ointment on the healing of Sadyavrana (incised wound). Observations: Progressively wound contraction was assessed on 0 days, 4th, 8th, 12th, and 16th days in both groups using graph paper (mm2) and represented as a percentage. Result: the statistical analysis (unpaired t-test) revealed that there is a significant difference in the wound healing activity of both the ointments on Sadyavrana (p<0.0001). Discussion: Dhataki extract is antibacterial and antifungal. Tannins and alcohol concentration may speed wound contraction and healing. Reduced wound contraction indicates Dhataki ointment's superiority over betadine. Conclusion: Dhataki flower ointment has a significant effect on Sadyavrana when compared with betadine ointment.
A comprehensive study of Urvi Marma - The vital point mentioned by Acharya Sushruta
Authors: Jungade Leena G , Shelke Dinbandhu S , Bathe Anupama M , Chandurkar Nitin S , Kalangutkar Dipti D
Published: October 2022

Marma science (traumatology) is a unique specialty of Ayurveda that plays a significant role in surgical procedures and treatments. Acharya Sushruta has described Urvi Marma as part of the Sira marma (a vital point which is vascular in nature), and he has mentioned the traumatic disorders associated with it. In order to apply Acharya Sushruta's invaluable knowledge of Urvi Marma in the current era, it is necessary to precisely correlate his concept of Urvi Marma with present Anatomical perspectives. This research aims to bridge the gap between old wisdom and current science. Material and Methods: A comprehensive review of the literature on the concept of Marma Sharir (traumatology) and Urvi Marma was conducted, taking into account the position of Urvi Marma as told by our ancient experts. The anatomy of the thigh, as well as its application, has been researched through numerous books and dissection.
Standardization of Dooshivishahari Agada through HPTLC
Authors: P Deepa , H R Nataraj , H N Prajwal , C G Anushree
Published: October 2022

Ayurveda medicines are a time-tested and valuable resource for healing, even today, globally. Hence the quality control standards for the Ayurvedic formulations is the need of time because of commercialization. Despite the availability of modern equipment and techniques, not all  Ayurvedic formulations have been standardized as per modern day protocol. Dooshivishari agada (DVA), a herbo-mineral preparation; mentioned in the text of Asthangha hrudaya in the context of treatment of poisoning, specifically for dooshivisha (cumulative poison). High-performance thin-layer chromatography (HPTLC) is a validated analytical tool for qualitative and quantitative analysis of chromatographic information. In this present study, an effort has been made to standardize DVA through HPTLC. HPTLC photo documentation of DVA showed 8, 11, and 10 spots under short UV, long UV, and under white light after derivatization respectively. Densitometric scan at 254 nm revealed 3 high peaks corresponding to 3 different compounds in the ethanol extract, compounds, at 366 nm and 620 nm there were three high peaks. These Physico-chemical constants, TLC photo documentation, the unique Rf values, and densitogram obtained at different wavelengths can be used as a fingerprint to identify DVA.
Association of Viharaj Hetus (External and Environmental Factors) with Shirahshool (Headache) – A cross sectional study
Authors: Sanghmitra Randhir , Vinayak Joshi Mrudula , Nilkanth Joshi Vinayak
Published: October 2022

Background- Shirahshool (headache) encompasses all the aches and discomforts associated in the Shira(head) region and is described under the caption of Shiroroga in Ayurveda texts. Aharaj (diet related) and Viharaj (external and environmental) Hetus are the main causative factors for any disease; yet the external and environmental factors also play an  important role in Shirahshool. Aim-To observe the role of Viharaj Hetus for their association with Shirahshool .Study Design-This cross sectional study was conducted amongst the pre diagnosed Shirahshool patients, both male and females from the age group 20-60 years, who were suffering for more than one year and get Shirahshool for more than 30 minutes every time. A structured, pilot tested questionnaire with 15 questions validated by scientific committee was used to collect the information. Statistical analysis- The collected data is qualitative Pearson correlation test and Chi square test is used to test the association between Viharaj Hetus and Shirahshool. P- Value  less than 0.05; which was considered as significant association. Result- Amongst Viharaj Hetus, Shita Vayu Sewan (cold air exposure-external environmental factor) was present in maximum number of patients i.e. 40 %, Nidra Vega Vidharana (suppression of the urge for sleep) in 36%, Asatmya Gandha Sewan(bad odour) in 31 % of total Shirahshool patients. Conclusion- The highest  incidence of Shiroroga based on chronicity (59%) is in between 1-5 years with the duration for 30-60 minutes and based on severity 46% with moderate grade of Shirashool. Exposure to cold air and suppression of urge for sleep are the causative factors found as important with respect to duration of exposure whereas anger was noted as major, immediate Hetu of Shirahshool. Thus the association of Viharaj hetus with Shirahshool is of very much importance with respect to diagnosis, prevention and treatment
A Comprehensive Siddha review of Kuttam W.S.R to Psoriasis
Authors: Rathinam Rathinamala , Balasubramaniam Vinu Bharathi , Vaidhiyanathan Hariharan Vishnupriya , Arumugam Rajendra Kumar
Published: October 2022

According to Siddha science the imbalance or disturbance of the trihumours (Vatham, Pitham, Kabam) leads to a disease. The total number of diseases in Siddha system of medicine is said to be 4448, the sub classification, methodology and enumeration differs from one author to other. Skin diseases in Siddha system of medicine can be brought under a common entity Kuttam. Psoriasis is formally termed as Kalanjagapadai in Siddha, and the symptoms of which can be correlated with the aforesaid. The objective of this article is to provide deep descriptive information regarding different school of thoughts on Kalanjagapadai (Psoriasis). A comprehensive literature review to identify the available literary evidences and published data on Kuttam with a particular highlight to Kalanjagapadai (Psoriasis) was carried out. A number of 11 literatures were identified to be dealt about Kuttam and Plaque Psoriasis is alluded in most of the literatures however with different terminologies. Emotional disturbances are the common etiologic factors mentioned in almost all Siddha texts. 17 dissertations have also been identified with two keywords Kuttam and Kalanjagapadai. Out of which 16 of them are Clinical Trials and another one is based on the Siddha diagnostic tool on Psoriasis. This article also elaborates the classical details of Kuttam that can be correlated with the clinical features of Kalanjagapadai along with its modern counterpart.
Evaluation of Acute and Long-term Toxicity of Siddha Formulation Annabethi Chendhuram
Authors: G Kavitha , B Neethi , T Subathra , P Shanmugapriya
Published: October 2022

Introduction: Annabethi Chendhuram is extensively used for the treatment of anaemia by Siddha practitioners. But concerns about the safety of drugs are raised in the current era due to a lack of scientific validation. Aim: The present study was conducted to determine the acute and long-term toxicity of Annabethi chendhuram. Methods: Acute and long-term toxicity of Annabethi chendhuram were evaluated as per WHO guidelines in Wistar albino rats. In the acute study, 250mg/kg.b.wt of test drug was given for animals then observed for any toxic signs and mortality up to 14 days. In a long-term toxicity study, a test drug was administered at the dose of 25, 125 and 250mg/kg/b.wt/p.o/day for animals up to 90 days and observed for mortality and morbidity. All animals were sacrificed at the end of the study. Haematology, biochemical parameters and histopathological examination were analyzed. Result: In the acute toxicity study, no toxic signs or death were observed in all animals. In the long-term toxicity study, no significant differences were observed in body weight changes, food intake, water intake, haematology, biochemical parameters and histopathology of both control and test groups. Conclusion: The study result concludes that the long-term oral administration of 250 mg/kg.b.wt of Annabethi chendhuram did not cause any toxic effect in rats. So, the drug is safe for human consumption.
Influence of Deha-Prakriti (Body Constitution) in the manifestation of disease in context to Amavata (Rheumatoid Arthritis) - An appraisal
Authors: Chinthala Rajkumar , NNL Bhagavathi
Published: October 2022

Deha-Prakriti (DP) is Ayurveda’s one-of-a-kind contribution, established at conception and cannot be changed throughout one’s life. There are seven varieties of DP. Vataja, Pittaja, Kaphaja (Shleshmala), Samsargaja [combination of two Dosha] i.e. Vata-Pittaja, Pitta-Kaphaja, Kapha-Vataja, Sannipataja [combination of three Dosha] i.e. Vata-Pitta-Kapha. The first and most important aspect of Dashavidha-parikshyabhavas (ten important examination factors to be known by the physician) is the DP assessment since it plays a crucial part in Rogi-Pariksha (evaluation of the patient) and Roga-Pariksha (assessment of the disease). DP allows a physician to assess the condition of Koshtha (digestion system), Agni (digestive capacity), Bala (strength), and Ayu (life-span) in both healthy and diseased people. It may also help a physician forecast illness susceptibility, severity of signs and symptoms, disease activity scores, and bio-markers such as hematological, pathological, and biochemical indicators. Based on the severity, a physician may prepare the appropriate diet-chart, medication, dose, Anupana (co-drink to the primary medicine), and treatment technique (either Shodhana karma- purificatory measure or Shamana karma- Palliative measure). In light of the above facts, the current study aims to explore the DP-based susceptibility to Amavata, its severity, and the research strategy for future studies. An overview of evidence-based study on developing Deha-Prakriti with diverse illness conditions may be provided in this work, allowing for the revalidation of ayurvedic literature-based assertions.
An overview of nephroprotective plants in the Indian traditional system of Medicine
Authors: N Srinivasan
Published: October 2022

Renal diseases have emerged as a critical health problem that has a significant impact on human health. One of the most prevalent kidney issues is nephrotoxicity, which happens when the body is exposed to a medicine or toxin. As a result of the kidneys being damaged by major factors such as ischemia, hypoxia, antibiotics, chemotherapy, and NSAIDS, the condition known as acute renal failure can develop. Due to the high mortality rate associated with acute renal failure, it is a serious challenge for healthcare workers. A lack of oxygen and nutrients is a primary cause of nephrological disorders, which are exacerbated by oxidative stress and poor nephron circulation. Thus, the thought of antioxidants being used to prevent kidney disease is always an intriguing one that deserves extensive discussion. It has long been known that medicinal plants possess antioxidant properties, which may be helpful for the recovery of kidney problems. For a long time, many herbs and their formulations have been used in traditional medicine to treat kidney problems without having any side effects. The search for nephroprotective medicinal plants and their phytoconstituents was conducted using a wide range of electronic databases including PubMed, Google Scholar, etc. The primary purpose of the review article was to provide a comprehensive overview of known nephroprotective plants, as well as research-based data on mechanisms, active phytocomponents, sources, and potential applications relevant to the prevention and treatment of kidney disorders.
Understanding of Post Covid Mucormycosis through the Lens of Ayurveda
Authors: Bathe Anupama M , Thanvi Harsha , Dipankar Digambar , Jungade Leena , Varghese Jibi , Mane Pallavi
Published: October 2022

Mucormycosis is fungal disease caused by fungus Mucor. It has been seen as a life-threatening complication of disease Covid-19. It has 70 times higher prevalence rate in India as compared to the world, having only few but expensive treatment options. The triggers of Mucor infection in Covid-19 patients are immune deficiency and hyperglycaemia caused by the use of corticosteroid, which favours Mucorales tissue Penetration. Mucormycosis has mainly six different types viz pulmonary, rhino-orbital-cerebral, gastrointestinal, widely disseminated, cutaneous, & miscellaneous infection, the commonest clinical presentation is rhino-orbito-cerebral in Covid-19 pandemic.

Ayurveda though an ancient science of healing, has strength to treat newer diseases from several decades. Mucormycosis disease is not mentioned in Ayurveda text directly, it is Un uttered disease (Anukta Vyadhi) but it can be treated with help of basic principles of Ayurveda. By understanding the pathogenesis, it can be stated that, it is an Abhishangaja Vyadhi   (diseased caused by Virus/ Bacteria/ Parasite) and categorised as Raktapitta Pradhan Tridoshaja Vyadhi (disease caused by vitiation of all three humors with rakta pitta predominance).

Prevention of Mucormycosis can be achieved by following daily (Dincharya) and seasonal (Ritucharya) regimens. The treatment protocol include Krimighna (Antimicrobial),  Tridoshashamak (normalise all three humors) and Raktashodhaka /Pittashamak (blood purifier), Agnideepak (improve digestion) & Aampachak (improve metabolism), Pramehhar (treatment of diabetes/hyperglycaemia) and Rasayana (Rejuvenation) drugs.

 

Key words- Abhishangaj vyadhi, Anukta Vyadhi, Mucormycosis , RaktaPitta Pradhan Tridoshaj Vyadhi
Pharmaceutico analytical study of Guduchyadi Avaleha - Modified form of Guduchyadi Ghrita
Authors: Rudey Megha , Rathi Renu , Rathi Bharat
Published: October 2022

Introduction- Stuttering (Gadgada) word itself indicates the disease in which fluency of speech is impaired. It denotes the un-cleared speech (Avyakta Vak or Shabdha). In Vangsen Samhita, the group of 8 drugs with honey is cited for the treatment of stuttering entitled as Guduchyadi Ghrita. Palatability of Guduchyadi Ghrita is the major concern in the treatment of children to administer as most of children unlike it, so by keeping this in mind Avaleha formulation is prepared which is easily administrable. Guduchyadi Avaleha is a herbo-mineral confection which is prepared by using sugar as a base. This herbal compound is formulated by experienced Aacharya of Ayurved and is used in practice for stuttering. Though it’s a potent formulation; but no standardized reports are available for the manufacturing process of the Guduchyadi Avaleha or its preliminary physico-chemical profiles. Therefore, manufacturing standardize process of preparation and preliminary physic-chemical profiles of Guduchyadi leha was planned. Methods- The prepared lickable formulation was lay open for the analysis of pharmacognostical and pharmaceutical properties like as pH value, Microscopic analysis, loss on drying the sample, reading of  ash value, etc. Results – After analysis of Pharmacognostical organoleptic study, loss on drying value, pH, Ash value, Water soluble extract, the result was shown. Conclusion –All the characteristic of formulation sample was observed and the result can be taken as standard value for guduchyadi avaleha.
Pharmaceutical development of polyherbal Kushthaghna Mahakashaya lotion with FTIR and HPTLC characterization
Authors: Pandey Shivani , R S Hiremath , V S Mannur
Published: October 2022

Introduction: Kushthaghna Mahakashaya is a traditional herbal group of ten medicaments (dashemani) explained in classical texts and administered in the form of kashaya (decoction) indicated for the management of Kushtha (skin ailments). In the present scenario, based on disadvantages of the kashaya like lesser shelf-life, cumbersome, difficult to prepare and administer on a daily basis. Furthermore, if it is administered by an external route then, it may avoid first-pass metabolism and thereby enhancing the drug’s bioavailability and causing its rapid action. So, the present study is an attempt to prepare and analyze the modified dosage form of Kushthaghna Mahakashaya Kwatha in the form of Kushthaghna Mahakashaya Lotion. Materials and methods: Kushthaghna Mahakashaya Churna, Ghana, and Lotion were all prepared. Lotion was made by mixing the aqueous and oil phases together at the same temperature. It was stabilized with Carbopol and neutralized with Triethanolamine to improve the sample's stability. Different trials were conducted to check the excipient ratio in the formulation, and samples were evaluated according to standards. Organoleptic parameters, physico-chemical analysis, FTIR, HPTLC, and microbiological specification tests were all performed on the Ghana and Lotion. Results: All the tests and observations were carried out on Kushthaghna Mahakashaya Ghana and Lotion samples, and the results were recorded. Conclusion: Kushthaghna Mahakashaya Lotion can be prepared from Kushthaghna Mahakashaya Kwatha. The prepared lotion will be light brown in colour, characteristic smell and semi-liquid in consistency with good spreadibility.
Study of combined effect of Khadirashtak kwath and Lodhradi lep on Mukhdushika (Acne Vulgaris) – A pilot study
Authors: Deshpande Amol , Deshpande Mayuri Amol , Desai Priti
Published: October 2022

Introduction: Skin is one of the five Gyanendriyas (Sense organ) as described in Ayurvedic texts. It is responsible for Sparshdyanam, hence plays important role in Physical and Mental well being. It plays the most important role by interfacing with surrounding. On contrary with this there is increased pollution, stress, change in diet, change in life style causing the most burning skin problem i.e. Mukhdushika so called Acne Vulgaris. In modern science most of the drug which are used have side effect and complications on long term used, so Ayurveda is an best option to treat the diseases. Lodhradilep mentioned in Samhita can be used for external application and Khadirashtak kwath can be used for internal application. It can be used as alternate therapy which is devote of complication and side effect. Aim: To evaluate the efficacy of Lodhradi lep and Khadirashtak kwath on Mukhdushika. Objectives: To study the effect of Lodhradi lep and Khadirashtak kwath on Mukhdushika. Methodology: Ten patients of Mukhdushika (acne) were enrolled into this pilot study. All patients were evaluated on the basis number of  Pidikas (acne), Area Occupied, Kandu (itching), Srava (secretions), Vedana (pain). After 28 days of administration of Lodhradilep and Khadirashtak Kwath twice in a day after meal; result was analysed by paired t test. Results and conclusions: The result in all symptoms i.e. number of  Pidikas (acne) (P = <0.001), Area Occupied(P = 0.001), Kandu (itching) (P = <0.001), Srava (secretions) (P = <0.001), Vedana (pain) (P = <0.001)) was found statistically significant. Thus Lodhradi lep and Khadirashtak Kwath on Mukhdushika is an effective combination for management for Mukhdushika.