bluuebunny/crossref_metadata_2025 huggingface dataset:
Behavioral guidance for improving dental care in autistic spectrum disorders
Authors: Pastore Irene , Bedin Elena , Marzari Giulia , Bassi Francesca , Gallo Claudio , Mucignat-Caretta Carla
Published: November 2023

Introduction

Autism spectrum disorders (ASDs) impair many aspects of everyday life and may prevent access to dental care, often limiting it to emergencies. Impaired oral health has long-lasting negative consequences on health status and on the acquisition of oral habits (e.g., oral respiration and grinding) or competencies (e.g., proper speech production). Children with ASD may be scared in the dental setting, which is rich in sensory stimuli and requires physical contact. Due to their behavioral manifestations, they represent a challenge for dentists and hygienists. We created a dedicated pathway with behavioral support for children with ASD to allow dental care and possibly limit the use of general anesthesia.

Methods

We evaluated the effects of behavioral support in a quasi-experimental design by comparing two groups of children with ASD. The first group (n = 84) was visited every 2 months for 3 years and received additional support (visual aids, caregiver training, and longer visit duration). A control group, matched for age and sex, was visited at least twice a year or more, if needed, according to standard healthcare guidelines.

Results

Compliance with the schedule was high throughout the 3 years. The degree of collaboration significantly improved after 1 year in the supported group, while the control group did not change. At the end of the study, collaboration remained significantly higher than at the beginning in the supported group. Half of dental treatments were possible without general anesthesia in supported children. No adverse effect was apparent on collaboration due to COVID-19 restrictions.

Discussion

Behavioral techniques improved the compliance of ASD children to regular dentistry visits and treatment. Furthermore, oral hygiene at home was similarly improved, addressing oral health from a lifelong perspective.
Stress and sleep quality in medical students: a cross-sectional study from Vietnam
Authors: Tran Duc-Si , Nguyen Duy-Thai , Nguyen Thai-Hang , Tran Cao-Thinh-Phuoc , Duong-Quy Sy , Nguyen Thanh-Hiep
Published: November 2023

Background

The COVID-19 pandemic has resulted in significant global social and economic disruptions, as well as changes in personal attitude and behavior. The purpose of this research is to assess the sleep quality and stress levels of medical students.

Method

Data was collected from medical students over the course of a month in 2021. A total of 4,677 students at the University of Medicine Pham Ngoc Thach were invited to complete an anonymous web-based survey, which included the Pittsburgh Sleep Quality Questionnaire Index (PSQI) for measuring sleep quality and the COVID-19 Student Stress Questionnaire (CSSQ) for evaluating stress.

Results

A total of 1,502 students participated in our survey. More than half of the participants exhibited poor quality of sleep as indicated by their PSQI score. Many students reported going to bed after midnight and spending time on their smartphones. Among the students surveyed, 21.84% experienced low levels of stress (CSSQ ≤6), 63.38% had mild stress (7 ≤ CSSQ score ≤ 14), 14.78% reported high levels of stress (CSSQ >14).

Conclusion

This study showed a high prevalence of poor sleep quality in the surveyed students, which could be attributed to changes in their behavior following the COVID-19 outbreak. Mild stress was also frequently observed, and it may be related to sleep disorders in this population. These important findings provide valuable insights for making recommendations, including lifestyle modifications to improve sleep quality.
Multiple change point analysis of hepatitis B reports in Xinjiang, China from 2006 to 2021
Authors: Yang Liping , Xie Na , Yao Yanru , Wang Chunxia , RiFhat Ramziya , Tian Maozai , Wang Kai
Published: November 2023

Objective

Hepatitis B (HB) is a major global challenge, but there has been a lack of epidemiological studies on HB incidence in Xinjiang from a change-point perspective. This study aims to bridge this gap by identifying significant change points and trends.

Method

The datasets were obtained from the Xinjiang Information System for Disease Control and Prevention. Change points were identified using binary segmentation for full datasets and a segmented regression model for five age groups.

Results

The results showed four change points for the quarterly HB time series, with the period between the first change point (March 2007) and the second change point (March 2010) having the highest mean number of HB reports. In the subsequent segments, there was a clear downward trend in reported cases. The segmented regression model showed different numbers of change points for each age group, with the 30–50, 51–80, and 15–29 age groups having higher growth rates.

Conclusion

Change point analysis has valuable applications in epidemiology. These findings provide important information for future epidemiological studies and early warning systems for HB.
Impact of food insecurity and food environment on the diet quality of older African Americans during the COVID-19 pandemic
Authors: Kibe Lucy W. , Schrode Katrina , Bazargan Mohsen , Shaheen Magda
Published: November 2023

Introduction

A high quality diet is vital in promoting wellbeing and ensuring good health, particularly for those living with chronic conditions. Older African Americans, already burdened with a higher prevalence of chronic conditions, also face a higher risk for suboptimal diets. The COVID-19 pandemic had lasting effects on access to healthy food for all Americans, but some demographic groups were disproportionately affected. Older African Americans, who already experienced reduced access to healthy food pre-pandemic, were particularly afflicted, but the full extent of the pandemic's impact on their food insecurity and food environment remains unclear.

Methods

To address this gap, we conducted a study among 102 older African Americans in South Los Angeles between October 2021 and July 2022 during the COVID-19 pandemic. Participants completed surveys on dietary intake, food insecurity, and neighborhood food environment. We measured dietary quality using the healthy eating index (HEI)-2015. The analysis included descriptive, bivariate chi-square, t-tests, analysis of variance, and multiple linear and logistic regression.

Results

While overall dietary quality was suboptimal, most participants met the guidelines for fruit and vegetable consumption. Food insecurity was associated with lower overall diet quality and lower total fruit and whole fruit intake. However, there was no association between food environment and diet quality.

Discussion

In light of our findings, further intervention is critical to improving diet quality, especially among older African Americans living with chronic conditions in the post-pandemic era.
Chain mediations of perceived social support and emotional regulation efficacy between role stress and compassion fatigue: insights from the COVID-19 pandemic
Authors: Zhang Yuan , He Huijuan , Yang Chongming , Wang Xiangrong , Luo Jiang’an , Xiao Jie , Fu Bei , Chen Yiwen , Ma Chenjuan
Published: November 2023

Background

Nurses at the frontline faced high risks of the COVID-19 infection, undertook heavy workloads of patient care, and experienced tremendous stress that often led to compassion fatigue.

Aim

This study was to explore the role of positive psychosocial resources (i.e., perceived social support and emotional regulation efficacy) in the relationship between role stress and compassion fatigue.

Methods

A cross-sectional design was conducted in Hubei Province, China between May and September 2021. The Role Stress Questionnaire, the Perceived Social Support Scale, the Emotional Regulation Efficacy Scale, and the Professional Quality of Life Scale were used to measure key variables of interest. Nurse socio-demographic data were also collected. Structural equation modeling was used to explore the relationships, including potential mediating effect, among role stress, perceived social support, emotional regulation efficacy, and compassion fatigue.

Results

A total of 542 nurses participated in this investigation, and 500 were eventually enrolled in the analysis. The incidence of compassion fatigue among nurses was 94.2%, including 65.8% of nurses reporting at least moderate compassion fatigue. Univariate analysis showed that educational level, marital status, hospital rank, sleep time were the factors affecting compassion fatigue of the nurses. The structural equation modeling revealed that: Role stress had a direct positive effect on compassion fatigue; Perceived social support and emotional regulation efficacy partially mediated the link between role stress and compassion fatigue respectively; And there was a chain mediating role of perceived social support and emotional regulation efficacy between role stress and compassion fatigue.

Conclusion

The incidence of compassion fatigue was high during the COVID-19 pandemic among bedside nurses in China. Improving social support and enhancing the efficacy of emotion regulation may help alleviate compassion fatigue directly and/or via buffering the impact of role stress.
Assessing perceived participation among older adults total hip arthroplasty and total knee arthroplasty patients six months post-surgery: a cross-sectional study
Authors: Yao Lifeng , Jia Qin , Wu Jiayun , Chai Yufei , Gao Chu , Wang Yingying , Li Ke , Lai Meihong
Published: November 2023

Aims

This research sought to assess the perceived levels of participation and autonomy in senior patients who had received total hip arthroplasty (THA) or total knee arthroplasty (TKA) in Hangzhou, China. Furthermore, the study aimed to identify the factors linked to these outcomes.

Study design

This investigation will utilize a cross-sectional study design to assess perceived participation and autonomy among older adults total hip arthroplasty (THA) and total knee arthroplasty (TKA) patients. The research was conducted in Hangzhou, China, at a tertiary hospital.

Methods

Convenient sampling was utilized to select 139 patients who underwent THA or TKA between March 2022 and March 2023 and met the inclusion criteria at a tertiary hospital in Hangzhou. The Impact on Participation and Autonomy Questionnaire, Hip/Knee Injury and Osteoarthritis Outcome Score (HOOS/KOOS), 5-Item Geriatric Depression Scale, Multidimensional Scale of Perceived Social Support, and Elders Health Empowerment Scale were used to assess perceived participation, hip/knee-related symptoms and functional restrictions, depression symptoms, social support, and health empowerment.

Results

The mean score for perceived participation and autonomy was 22.554 (SD: 13.042). The mean scores for participation in indoor autonomy, outdoor autonomy, family roles, and social relations were 0.654 (SD: 0.608), 1.324 (SD: 0.792), 1.053 (SD: 0.657), and 0.664 (SD: 0.542), respectively. Negative correlations were observed between perceived participation/autonomy scores and HOOS/KOOS, social support, and health empowerment scores. Conversely, a positive correlation was found between perceived participation/autonomy scores and depression scores. The detrimental effect of HOOS/KOOS, social support, and health empowerment scores on perceived participation and autonomy was notable, while the impact of depressive symptoms was comparatively minor.

Conclusion

Older Chinese patients, at first six months post THA/TKA surgery, reported higher levels of perceived participation compared to individuals with other conditions, such as stroke patients. Functional limitations resulting from hip/knee-related symptoms, as well as social support and health empowerment, emerged as significant influencing factors for perceived participation and autonomy. This research enhances our comprehension of the elements influencing perceived participation among older adults individuals who have undergone THA/TKA procedures.
Single-case design meta-analyses in education and psychology: a systematic review of methodology
Authors: Moeyaert Mariola , Dehghan-Chaleshtori Marzieh , Xu Xinyun , Yang Panpan
Published: November 2023

Meta-analysis is of increasing importance as this quantitative synthesis technique has the potential to summarize a tremendous amount of research evidence, which can help making evidence-based decisions in policy, practice, and theory. This paper examines the single-case meta-analyses within the Education and Psychology fields. The amount of methodological studies related to the meta-analysis of Single-Case Experimental Designs (SCEDs) is increasing rapidly, especially in these fields. This underscores the necessity of a succinct summary to help methodologists identify areas for further development in Education and Psychology research. It also aids applied researchers and research synthesists in discerning when to use meta-analytic techniques for SCED studies based on criteria such as bias, mean squared error, 95% confidence intervals, Type I error rates, and statistical power. Based on the summary of empirical evidence from 18 reports identified through a systematic search procedure, information related to meta-analytic techniques, data generation and analysis models, design conditions, statistical properties, conditions under which the meta-analytic technique is appropriate, and the study purpose(s) were extracted. The results indicate that three-level hierarchical linear modeling is the most empirically validated SCED meta-analytic technique, and parameter bias is the most prominent statistical property investigated. A large number of primary studies (more than 30) and at least 20 measurement occasions per participant are recommended for usage of SCED meta-analysis in Education and Psychology fields.
The Zero Emissions Commitment and climate stabilization
Authors: Palazzo Corner Sofia , Siegert Martin , Ceppi Paulo , Fox-Kemper Baylor , Frölicher Thomas L. , Gallego-Sala Angela , Haigh Joanna , Hegerl Gabriele C. , Jones Chris D. , Knutti Reto , Koven Charles D. , MacDougall Andrew H. , Meinshausen Malte , Nicholls Zebedee , Sallée Jean Baptiste , Sanderson Benjamin M. , Séférian Roland , Turetsky Merritt , Williams Richard G. , Zaehle Sönke , Rogelj Joeri
Published: November 2023

How do we halt global warming? Reaching net zero carbon dioxide (CO2) emissions is understood to be a key milestone on the path to a safer planet. But how confident are we that when we stop carbon emissions, we also stop global warming? The Zero Emissions Commitment (ZEC) quantifies how much warming or cooling we can expect following a complete cessation of anthropogenic CO2 emissions. To date, the best estimate by the Intergovernmental Panel on Climate Change (IPCC) Sixth Assessment Report is zero change, though with substantial uncertainty. In this article, we present an overview of the changes expected in major Earth system processes after net zero and their potential impact on global surface temperature, providing an outlook toward building a more confident assessment of ZEC in the decades to come. We propose a structure to guide research into ZEC and associated changes in the climate, separating the impacts expected over decades, centuries, and millennia. As we look ahead at the century billed to mark the end of net anthropogenic CO2 emissions, we ask: what is the prospect of a stable climate in a post-net zero world?
Development of Hexagonal Pyramid-Shaped Flexible Actuator with Anisotropic Stiffness for Upper-Limb Rehabilitation Device
Authors: Shimooka So , Himuro Hiroki , Gofuku Akio
Published: November 2023

Rehabilitation devices for passive exercise have been actively researched and developed in accordance with Japan’s aging society. A previous study proposed and tested an extension-type flexible pneumatic actuator (EFPA) with reinforced stiffness that could achieve passive exercise in patients. In addition, a rehabilitation device for shoulder joints with an embedded controller and small valves was proposed and tested. Joints such as the shoulder and scapula were subjected to passive exercise utilizing the tested device. However, it is difficult for patients with contractions to perform the same exercise because the reinforced EFPA can buckle. Here, to realize an EFPA with a higher stiffness, a flexible actuator in the shape of a hexagonal pyramid is proposed and tested. The hexagonal pyramid shape of a flexible actuator has a high stiffness in the direction of motion and flexibility in other directions; hereafter, this characteristic is called anisotropic stiffness. The characteristics of the hexagonal pyramid shape of the EFPA are described and compared with those of a previously reinforced EFPA. An analytical model was proposed to predict and design the shape of the hexagonal pyramid EFPA. The validity of the model is also described.
Multi-Criteria Evaluation Model of Management for Weaned Piglets and Its Relations with Farm Performance and Veterinary Medicine Consumption
Authors: Sanz-Fernández Santos , Díaz-Gaona Cipriano , Borge Carmen , Quintanilla Raquel , Rodríguez-Estévez Vicente
Published: November 2023

Weaned piglets, being immature, demand careful handling to mitigate post-weaning stress in order to avoid immunosuppression and the use of antimicrobials to palliate the effects of disease outbreaks due to poor management. The objective of this work is to design a quick scan calculator or multi-criteria evaluation model of management for weaned piglets, founded on 10 critical indices covering post-weaning management aspects based on hygienic measures and management of facilities and animals. These include pre-weaning handling, batch management, biosecurity, water management, feed management, health program, stockmen training, temperature, ventilation, and floor conditions and density to relate handling and hygiene practices with farm performance and the consumption of veterinary medication. Each index carries a maximum score of ten, with evaluations derived from different management factors that make up each index (from three to eight factors were evaluated per index). Their cumulative score reflects the degree of adequacy of on-farm management. Therefore, a perfectly managed farm would achieve 100 points. The calculator underwent testing on 23 intensive farms with a total population of close to 16,000 sows and more than 400,000 weaned piglets, revealing the highest mean scores in floor conditions and density (8.03 out of 10) and pre-weaning handling and health programs (6.87 and 6.28, respectively). Conversely, the lowest scores corresponded to temperature, ventilation, water management, and stockmen training (4.08, 4.32, 4.81, and 4.93, respectively). The assessed farms averaged a global score of 56.12 out of 100 (from 37.65 to 76.76). The calculator’s global score correlated with key post-weaning productivity and piglet health indicators, such as the feed conversion ratio, mortality rate, and piglet production cost, with r values of −0.442, −0.437, and −0.435, respectively (p < 0.05). Additionally, it negatively correlated with medication costs per piglet (r = −0.414; p < 0.05) and positively with annual farm productivity (r = 0.592; p < 0.01). To enhance management, hygiene, and prevention, farms should prioritize addressing indices with the lowest scores, thereby reducing medication consumption and enhancing productivity and health outcomes. Additionally, this quick scan calculator can be used for benchmarking purposes.
Effects and Mechanisms Investigation of Heat Stress on Egg Yolk Quality in Huaixiang Chickens
Authors: Chen Yuxia , Yu Sumeng , Zhang Li , Xiao Mei , An Lilong
Published: November 2023

The purpose of this study was to examine the effects of high temperature on internal egg yolk quality parameters and their possible mechanisms in Huaixiang chickens. This study consisted of two treatments, and each treatment had six replicates with six birds per cage. A total of seventy-two 26-week-old female Huaixiang chickens were randomly divided into a normal-temperature group (NT) and a high-temperature group (HT) for 6 weeks. And these hens were exposed to 25 ± 2 °C and 32 ± 2 °C, respectively. Their relative humidity was maintained at 55–65%. The results showed that the HT group significantly reduced yolk weight, yolk color, and egg weight compared to the NT group (p < 0.05). Heat stress caused vacuolar degeneration of the liver and reduced the absolute liver weight (p < 0.05). Both yolk triglyceride (TG) and liver TG in the HT group were significantly higher than in the NT group (p < 0.05). However, the liver total cholesterol (TC) level in the HT group was remarkably lower than that in the NT group (p < 0.05). Additionally, heat stress remarkably enhanced SREBP-1c, ACACA, and FASN lipid metabolism-related gene mRNA expression levels in Huaixiang chicken liver after 6 weeks of heat exposure (p < 0.05). Furthermore, the HT group had remarkably reduced total amino acid, Cys, and Tyr levels in the yolk when compared with the NT group in our experiment (p < 0.05). In conclusion, heat stress causes egg yolk quality reduction and abnormal lipid metabolism in Huaixiang chickens. These findings provided novel insights into the role of high temperature on egg yolk parameters and the underlying mechanisms in Chinese indigenous laying hens.
In Vitro Digestibility and Models of Cumulative Gas Production of Forage-Free Diet
Authors: Ítavo Luís Carlos Vinhas , Gurgel Antonio Leandro Chaves , Ferreira Ítavo Camila Celeste Brandão , Cunha Camila Soares , Longhini Vanessa Zirondi , Difante Gelson dos Santos , Dias Alexandre Menezes , Santana Juliana Caroline Santos , Arcanjo Angelo Herbet Moreira , Niwa Marcus Vinicius Garcia , Nonato Lucimara Modesto , Tadeu dos Santos Geraldo , Chay-Canul Alfonso Juventino
Published: November 2023

Our objectives were to evaluate the use of cottonseed cake in replacing corn silage in a diet without forage and to identify the model with higher precision and accuracy of adjustment of parameters of ruminal degradation kinetics. A diet containing corn silage and another with cottonseed cake as a fiber source were formulated. Gompertz, Dual-pool Logistic, Brody, and Ørskov models were evaluated for goodness of fit to gas production. There were significant differences in dry matter (DM), organic matter (OM), and neutral detergent fiber (NDF) in the in vitro digestibility for diets and fiber sources. The estimated values of the Gompertz (6.77), Brody (6.72), and Ørskov (6.73) models were similar to the observed mean of gas production in the corn silage diet (6.73 mL/100 mg DM). Similarly, the estimated values of the Brody (5.87) and Ørskov (5.89) models were similar to the observed mean of gas production in the cottonseed cake diet (5.87 mL/100 mg DM). The roughage-free diet containing cottonseed cake as a fiber source stimulated higher gas production. Brody and Ørskov models presented higher precision and accuracy in the fitting of kinetics of degradation independent of the fiber source in the diet.
Bee Products for Poultry and Rabbits: Current Challenges and Perspectives
Authors: Abd El-Aziz Ayman , Abo Ghanima Mahmoud , Mota-Rojas Daniel , Sherasiya Anjum , Ciani Francesca , El-Sabrout Karim
Published: November 2023

Poultry and rabbit production are important and rapidly growing agricultural subsectors, particularly in several developing countries. To ensure the sustainability of poultry and rabbit production, realistic poultry and rabbit farming practices must be improved. Apitherapy is a traditional alternative medicine that involves the prevention and treatment of some diseases with several bee products including propolis, royal jelly, pollen, and venom. More feeding investigations on the numerous benefits of bee products for poultry and rabbits are crucial to be addressed. Poultry and rabbit production has recently experienced numerous challenges, including climate change, disease spread, and antibiotic misuse. Improving animal welfare, health, and production is a top priority for all livestock farms, as is supplying consumers with safe and healthy products. Therefore, this review aims to collect and investigate recent relevant literature on the use of bee products, as feed additives, drinking water supplements, and injections, for poultry and rabbits to improve animal health and production. From the current findings, bee products can improve the growth and immunological performance of small-livestock animals, such as poultry and rabbits, by activating digestive enzymes, maintaining microbial balance, and promoting vitamin synthesis. Therefore, bee products could be a promising natural alternative to growth promoters, reproductive stimulants, and immunological enhancers in poultry and rabbit farms to provide safe and healthy products for humans.
WERECE: An Unsupervised Method for Educational Concept Extraction Based on Word Embedding Refinement
Authors: Huang Jingxiu , Ding Ruofei , Wu Xiaomin , Chen Shumin , Zhang Jiale , Liu Lixiang , Zheng Yunxiang
Published: November 2023

The era of educational big data has sparked growing interest in extracting and organizing educational concepts from massive amounts of information. Outcomes are of the utmost importance for artificial intelligence–empowered teaching and learning. Unsupervised educational concept extraction methods based on pre-trained models continue to proliferate due to ongoing advances in semantic representation. However, it remains challenging to directly apply pre-trained large language models to extract educational concepts; pre-trained models are built on extensive corpora and do not necessarily cover all subject-specific concepts. To address this gap, we propose a novel unsupervised method for educational concept extraction based on word embedding refinement (i.e., word embedding refinement–based educational concept extraction (WERECE)). It integrates a manifold learning algorithm to adapt a pre-trained model for extracting educational concepts while accounting for the geometric information in semantic computation. We further devise a discriminant function based on semantic clustering and Box–Cox transformation to enhance WERECE’s accuracy and reliability. We evaluate its performance on two newly constructed datasets, EDU-DT and EDUTECH-DT. Experimental results show that WERECE achieves an average precision up to 85.9%, recall up to 87.0%, and F1 scores up to 86.4%, which significantly outperforms baselines (TextRank, term frequency–inverse document frequency, isolation forest, K-means, and one-class support vector machine) on educational concept extraction. Notably, when WERECE is implemented with different parameter settings, its precision and recall sensitivity remain robust. WERECE also holds broad application prospects as a foundational technology, such as for building discipline-oriented knowledge graphs, enhancing learning assessment and feedback, predicting learning interests, and recommending learning resources.
Changes in the Biological Activities of Gracilaria verrucosa Extracted Using Different Extraction Solvents
Authors: Kim Jin-Sol , Choi Chulyung , Lee Hyun-Hwa
Published: November 2023

This study investigated the antioxidant, antiaging, and antibacterial properties of Gracilaria verrucosa (GV) based on 95% methanol (GVM), ethanol (GVE), and hot water (GVW) extractions. Antioxidant activity assays revealed the total polyphenol and flavonoid contents were highest in GVM and GVE. The 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) and 2,2′-Azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) activities were highest in GVE and GVM. Furthermore, GVE exhibited the highest ferric-reducing antioxidant power (FRAP) value. In comparison, superoxide dismutase (SOD), catalase (CAT), and ascorbate peroxidase (APX) activities were highest in GVM. Collectively, GVE and GVM had stronger antioxidant activities than GVW. Additionally, collagenase, elastase, and tyrosinase inhibition assays showed that GVM exhibited the strongest anti-wrinkle and skin-whitening activities. Liquid chromatography–tandem mass spectrometer (LC–MS/MS) revealed that GVW had the highest 4-hydroxy benzoic acid content, whereas GVE had the highest naringenin and naringin contents. Additionally, GVE exhibited the strongest antimicrobial activity against six foodborne bacteria, with minimum inhibitory and bactericidal concentrations of 0.06–0.3 and 0.1–0.5 μg/μL. Correlation analysis of the GV extracts indicated a strong positive relationship between TPC and ABTS, SOD, and CAT activities (r = 0.760–0.982, p = 0–0.018). Overall, GVE and GVM can be applied to the development of functional agents across diverse industries.
Recognition of Additive Manufacturing Parts Based on Neural Networks and Synthetic Training Data: A Generalized End-to-End Workflow
Authors: Conrad Jonas , Rodriguez Simon , Omidvarkarjan Daniel , Ferchow Julian , Meboldt Mirko
Published: November 2023

Additive manufacturing (AM) is becoming increasingly relevant among established manufacturing processes. AM parts must often be recognized to sort them for part- or order-specific post-processing. Typically, the part recognition is performed manually, which represents a bottleneck in the AM process chain. To address this challenge, a generalized end-to-end workflow for automated visual real-time recognition of AM parts is presented, optimized, and evaluated. In the workflow, synthetic training images are generated from digital AM part models via rendering. These images are used to train a neural network for image classification, which can recognize the printed AM parts without design adaptations. As each production batch can consist of new parts, the workflow is generalized to be applicable to individual batches without adaptation. Data generation, network training and image classification are optimized in terms of the hardware requirements and computational resources for industrial applicability at low cost. For this, the influences of the neural network structure, the integration of a physics simulation in the rendering process and the total number of training images per AM part are analyzed. The proposed workflow is evaluated in an industrial case study involving 215 distinct AM part geometries. Part classification accuracies of 99.04% (top three) and 90.37% (top one) are achieved.
E-Cigarettes and Associated Health Risks: An Update on Cancer Potential
Authors: Sahu Rakesh , Shah Kamal , Malviya Rishabha , Paliwal Deepika , Sagar Sakshi , Singh Sudarshan , Prajapati Bhupendra G. , Bhattacharya Sankha
Published: November 2023

The potential cancer risk associated with electronic-cigarette (e-cigarette) use is ongoing and remains a subject of debate. E-Cigarettes work by heating a liquid that usually contains nicotine, flavorings, and other chemicals. When the liquid is heated, users inhale an aerosol into their lungs. While e-cigarettes are generally considered less harmful than traditional tobacco products, they still contain potentially harmful chemicals, which can damage DNA and lead to cancer. Several studies have investigated the potential cancer risk associated with e-cigarette use, while other studies have suggested that e-cigarette aerosol may contain carcinogenic chemicals that could increase the risk of lung and bladder cancer in humans. However, these studies are limited in their scope and do not provide conclusive evidence. Overall, the long-term cancer risk associated with e-cigarette use remains uncertain, more research is needed to fully understand the potential risks and benefits of e-cigarettes. However, this review will allow the investigator to get more recent updates about e-cigarettes.
Evidence and Modification of Non-Visual Eyestalk Organs in Troglobiont Mysida and Stygiomysida (Crustacea)
Authors: Wittmann Karl J.
Published: November 2023

Why do the eyes remain comparatively large, whereas the cornea is reduced in most troglobiont mysids? Are there any important organ size-dependent functions served by non-visual eye rudiments? This issue was approached by measuring eye structures in five troglobiont species of Mysida and two Stygiomysida compared with 14 troglophiles and 49 trogloxene Mysida species. The Organ of Bellonci (OB) was found in all Mysida and, as first records, also in Stygiomysida. The length of OBs increased with individual body length (BL) and eye length (EL) in four examined species: from postnauplioid larvae to adult stage in a troglophile and a trogloxene mysid species examined; and from juveniles to adults in a troglobiont mysid and a troglobiont stygiomysid. At the interspecific level, EL was, on average, 26% shorter at a given BL, while the OB was 40% longer at a given BL and 54% longer at a given EL, respectively, in adult troglobionts compared with trogloxene mysids. The OB is clearly proliferating, while the cornea is reduced in troglobionts. This points to sensory functions (possibly together with other functions). The sensory pore organ was found in all 15 Mysida species whose eyes were mounted on slides, and the first record of this organ was also found in Stygiomysida.
Simulating the Software Development Lifecycle: The Waterfall Model
Authors: Saravanos Antonios , Curinga Matthew X.
Published: November 2023

This study employs a simulation-based approach, adapting the waterfall model, to provide estimates for software project and individual phase completion times. Additionally, it pinpoints potential efficiency issues stemming from suboptimal resource levels. We implement our software development lifecycle simulation using SimPy, a Python discrete-event simulation framework. Our model is executed within the context of a software house on 100 projects of varying sizes examining two scenarios. The first provides insight based on an initial set of resources, which reveals the presence of resource bottlenecks, particularly a shortage of programmers for the implementation phase. The second scenario uses a level of resources that would achieve zero-wait time, identified using a stepwise algorithm. The findings illustrate the advantage of using simulations as a safe and effective way to experiment and plan for software development projects. Such simulations allow those managing software development projects to make accurate, evidence-based projections as to phase and project completion times as well as explore the interplay with resources.
Dynamic Path Planning for Unmanned Surface Vehicles with a Modified Neuronal Genetic Algorithm
Authors: Hamid Nur , Dharmawan Willy , Nambo Hidetaka
Published: November 2023

Unmanned surface vehicles (USVs) are experiencing significant development across various fields due to extensive research, enabling these devices to offer substantial benefits. One kind of research that has been developed to produce better USVs is path planning. Despite numerous research efforts employing conventional algorithms, deep reinforcement learning, and evolutionary algorithms, USV path planning research consistently faces the challenge of effectively addressing issues within dynamic surface environments where USVs navigate. This study aims to solve USV dynamic environmental problems, as well as convergence problems in evolutionary algorithms. This research proposes a neuronal genetic algorithm that utilizes neural network input for processing with a genetic operator. The modifications in this research were implemented by incorporating a partially exponential-based fitness function into the neuronal genetic algorithm. We also implemented an inverse time variable to the fitness function. These two modifications produce faster convergence. Based on the experimental results, which were compared to those of the basic neural-network-based genetic algorithms, the proposed method can produce faster convergent solutions for USV path planning with competitive performance for total distance and time traveled in both static and dynamic environments.
Physical and Chemical Characteristics of Explosive Dust at Large Open-Pit Coal Mines in Inner Mongolia, China and Dust Control Research
Authors: Yan Junlong , Wang Zhiming , Lu Xiang , Wu Yuejinyi , Luo Huaiting , Liu Xin
Published: November 2023

To further promote dust control efforts in Chinese open-pit coal mines, this study focuses on the research of coal dust and rock dust produced by different explosions in the Haerwusu open-pit coal mine in China. By investigating the relationship between the physical and chemical characteristics of dust particles from explosions in open-pit mines and the wetting properties of dust, the main factors influencing the wetting properties of explosive dust are identified. This provides a theoretical basis for subsequent dust control work in open-pit coal mines. Simultaneously, to formulate more effective dust suppressants and reduce explosive dust pollution, this study conducts experiments on the surface tension, contact angles, and complex solution compatibility to select suitable surfactants. Ultimately, the effectiveness of the dust suppressants is evaluated through permeability experiments and indoor dust suppression experiments. The research findings are as follows: (1) The significant factors affecting the wetting properties of coal dust are the fixed carbon content and D50, while the significant factor affecting the wetting properties of rock dust is D50. (2) The formulated dust suppressants can increase the permeation height of coal dust by at least 10 times, increase moisture absorption by at least 4 times, and reduce the TSP concentration by at least 81.4%.
Study on Characteristics, Influencing Factors and Health Benefits of Atmospheric Multi-Pollutants in Southern Xinjiang
Authors: Wang Jinyang , Ju Tianzhen , Lei Shengtong , Li Bingnan , Niu Xiaowen
Published: November 2023

In recent years, air pollution in Xinjiang, the core region of the Silk Road Economic Belt, has become increasingly severe, posing a more significant threat to human health. This paper selects the tropospheric ozone, nitrogen dioxide, and formaldehyde datasets under OMI remote-sensing monitoring and the PM2.5 dataset in China High Air Pollutants (CHAP) for 2018–2021. The spatial and temporal distribution of multi-pollutants, the spatial autocorrelation of Moran’s I index pollutants, and the correlation between pollutants in the warm period were studied in southern Xinjiang. Meanwhile, the geographical and temporal weighted regression (GTWR) model was used for influencing factor analysis, and the BenMap-CE model was used for health benefit analysis. The results showed that the spatial distribution of ozone concentration values in southern Xinjiang shows a decreasing distribution pattern from the east–central region to the western and southern regions. The spatial distribution of formaldehyde concentration values is opposite to that of ozone. There is a clear high-value area in the ozone concentration value in April–September. The NO2 column concentration values were in the range of 0.55~1.09 × 1015 molec/cm2 in most parts of southern Xinjiang. The area of high concentration values is located in the northeast of the study area; PM2.5 concentration values are higher in the middle area of southern Xinjiang. The spatial autocorrelation characteristics showed that the spatial aggregation of O3 and NO2 displayed a slow increasing trend year by year. The spatial aggregation of HCHO and PM2.5 fluctuated slightly in four years. The overall trend of HCHO is slowly decreasing, while PM2.5 is fluctuating and increasing. In the GTWR model analysis, overall, the atmospheric pressure has a strong influence on all pollutants. The effect of NO2 on O3 was higher than that of HCHO among the four pollutants. The correlation between O3 and PM2.5 was as high as −0.7872. The BenMap-CE health benefits assessment concluded that the number of premature deaths caused by ozone pollution was much higher than that of premature deaths caused by PM2.5. The highest number of premature deaths for both pollutants occurred in Kashgar.
Study on Strategy for Optimization of Thermal Comfort of College Courtyards in Lingnan Area in Summer
Authors: Tao Yiqi , Lou Yiyun , Chen Zebin , Zhao Fangyuan , Wang Weijen , Lin Xiaoyu
Published: November 2023

The campus courtyards in the Lingnan area are commonly used spaces. Therefore, their thermal comfort is highly important for improving user satisfaction. This study conducted field research on 18 courtyards in four universities in Lingnan to explore the effects of their architectural design factors on the thermal environment. Relevant studies have proved that courtyards are cost-effective in microclimate regulation, and individual factors such as the scale and openness of the courtyards have also been shown to have an effect on the thermal comfort of the courtyards. This study synthesizes multidimensional architectural design factors to explore and analyze the thermal environments of college courtyards. Physiologically equivalent temperature (PET) is selected as the thermal comfort evaluation index for the study and the conclusions are as follows: (1) The thermal environment is the most important factor influencing visitors to the courtyards (22%), and good thermal comfort improves the efficiency of using the college courtyards; (2) the courtyards have a positive microclimate regulating function, and a cooling effect occurs in 80% of them; and (3) the floor location, type, orientation, and sky view factor (SVF) of the courtyards are the main design factors affecting the thermal environment and PET. The first three factors were negatively correlated with PET (p < 0.05),and SVF was positively correlated with PET (p = 0.651). Passive courtyard design strategies are presented based on the findings of this study.
Monitoring Changes in Oxygen Muscle during Exercise with High-Flow Nasal Cannula Using Wearable NIRS Biosensors
Authors: Contreras-Briceño Felipe , Espinosa-Ramírez Maximiliano , Rivera-Greene Augusta , Guerra-Venegas Camila , Lungenstrass-Poulsen Antonia , Villagra-Reyes Victoria , Caulier-Cisterna Raúl , Araneda Oscar F. , Viscor Ginés
Published: November 2023

Exercise increases the cost of breathing (COB) due to increased lung ventilation (V˙E), inducing respiratory muscles deoxygenation (∇SmO2), while the increase in workload implies ∇SmO2 in locomotor muscles. This phenomenon has been proposed as a leading cause of exercise intolerance, especially in clinical contexts. The use of high-flow nasal cannula (HFNC) during exercise routines in rehabilitation programs has gained significant interest because it is proposed as a therapeutic intervention for reducing symptoms associated with exercise intolerance, such as fatigue and dyspnea, assuming that HFNC could reduce exercise-induced ∇SmO2. SmO2 can be detected using optical wearable devices provided by near-infrared spectroscopy (NIRS) technology, which measures the changes in the amount of oxygen bound to chromophores (e.g., hemoglobin, myoglobin, cytochrome oxidase) at the target tissue level. We tested in a study with a cross-over design whether the muscular desaturation of m.vastus lateralis and m.intercostales during a high-intensity constant-load exercise can be reduced when it was supported with HFNC in non-physically active adults. Eighteen participants (nine women; age: 22 ± 2 years, weight: 65.1 ± 11.2 kg, height: 173.0 ± 5.8 cm, BMI: 21.6 ± 2.8 kg·m−2) were evaluated in a cycle ergometer (15 min, 70% maximum watts achieved in ergospirometry (V˙O2-peak)) breathing spontaneously (control, CTRL) or with HFNC support (HFNC; 50 L·min−1, fiO2: 21%, 30 °C), separated by seven days in randomized order. Two-way ANOVA tests analyzed the ∇SmO2 (m.intercostales and m.vastus lateralis), and changes in V˙E and ∇SmO2·V˙E−1. Dyspnea, leg fatigue, and effort level (RPE) were compared between trials by the Wilcoxon matched-paired signed rank test. We found that the interaction of factors (trial × exercise-time) was significant in ∇SmO2-m.intercostales, V˙E, and (∇SmO2-m.intercostales)/V˙E (p < 0.05, all) but not in ∇SmO2-m.vastus lateralis. ∇SmO2-m.intercostales was more pronounced in CTRL during exercise since 5′ (p < 0.05). Hyperventilation was higher in CTRL since 10′ (p < 0.05). The ∇SmO2·V˙E−1 decreased during exercise, being lowest in CTRL since 5′. Lower dyspnea was reported in HFNC, with no differences in leg fatigue and RPE. We concluded that wearable optical biosensors documented the beneficial effect of HFNC in COB due to lower respiratory ∇SmO2 induced by exercise. We suggest incorporating NIRS devices in rehabilitation programs to monitor physiological changes that can support the clinical impact of the therapeutic intervention implemented.
BRAFV600E Positivity-Dependent Effect of Age on Papillary Thyroid Cancer Recurrence Risk
Authors: Park Joonseon , An Solji , Kim Kwangsoon , Bae Ja Seong , Kim Jeong Soo
Published: November 2023

BRAFV600E positivity is associated with increased aggressiveness of papillary thyroid cancer (PTC), and age is an important prognostic factor. However, the association between age and BRAFV600E positivity and the recurrence risk has not been investigated. This study aimed to investigate the impact of age on recurrence between patients with BRAFV600E-positive and -negative PTC. Patients with PTC who underwent initial thyroid surgery between January 2010 and December 2018 at Seoul St. Mary’s Hospital (Seoul, Republic of Korea) were retrospectively reviewed. The BRAFV600E-positive (n = 1768) and BRAFV600E-negative groups (n = 428) were divided into two subgroups: younger (<35 years) and older groups (≥55 years). In the BRAFV600E-positive group, the younger group exhibited higher lymphatic and vascular invasion rates, more positive lymph nodes, higher lymph node ratios, and higher recurrence rates than the older group (5.9% vs. 2.1%). Multivariate analysis revealed that age, lymphatic invasion, and N category were significant risk factors in the BRAFV600E-positive group. In the BRAFV600E-positive group, the younger group had a higher recurrence risk than the older group (OR, 2.528; 95% confidence interval, 1.443–4.430; p = 0.001). In the BRAFV600E-negative group, age had no impact on recurrence risk. These results contribute to tailored treatment strategies and informed patient management.