bluuebunny/crossref_metadata_2025 huggingface dataset:
A influência de fatores sociodemográficos na qualidade do sono do cuidador familiar de idosos com Doença de Parkinson e/ou Doença de Alzheimer no estado do Amapá
Authors: Leão Bruna da Silva , Araújo Yasmin Lorrane de Souza , Pureza Demilto Yamaguchi da , Lima Tainá Cristine Vilhena de , Silva Marlucilena Pinheiro da , Melim Lorane Izabel da Silva Hage- , Melo Débora Prestes da Silva
Published: September 2022

Objetivo: Caracterizar o perfil sociodemográfico dos cuidadores familiares de idosos com Doença de Parkinson (DP) e/ou Doença de Alzheimer (DA) no Estado do Amapá e identificar sua influência na qualidade do sono dos mesmos. Métodos: Trata-se de um estudo exploratório, descritivo de abordagem quantitativa realizado com 18 cuidadores familiares de pessoas com DP e/ou DA, por meio de entrevistas e utilização do Índice de Qualidade do Sono de Pittsburgh (PSQI). Este estudo foi desenvolvido no Município de Macapá, no Estado do Amapá. Resultados: A amostra apresentou em sua maioria mulheres 88,89%; menores de 60 anos 61,11%; filhos(as) 61,11%; prestando entre 3 a 6 anos de cuidado 50%. As categorias relacionadas à vida do cuidador foram: a qualidade do sono; entusiasmo na realização das atividades habituais; desempenho para o cuidado. Os cuidadores apresentaram poucas dificuldades de ficar acordado durante o dia e um grande problema de manter o entusiasmo. Conclusão: Conclui-se que a qualidade do sono dos cuidadores familiares está intrinsecamente relacionada com os fatores sociodemográficos, de modo que tais elementos influenciam em aspectos do cotidiano, como a sobrecarga do cuidador, qualidade do cuidado, qualidade do sono, relações familiares, e sobretudo na sua saúde e bem-estar.
MICROPLASTICS IN SOIL: IMPACTS ON ECOSYSTEMS, POTENTIAL SOURCES AND ANALYTICAL RESEARCH METHODS (REVIEW)
Authors: Носова А.О. , Успенская М.В.
Published: September 2022

Повсеместное использование пластмассы привело к увеличению количества пластикового мусора, накапливающегося в окружающей среде и разрушающегося на мелкие фрагменты, в том числе размером <5 мм – микропластик. За последнее десятилетие все большее количество исследований посвящается потенциальной опасности и методам анализа пластиковых частиц в водной среде. Однако, почвы могут быть загрязнены намного сильнее, при этом мало известно о накоплении микропластика в почве, возможных источниках, последствиях, взаимодействии пластиковых частиц с почвенными организмами и эффективных методах анализа. В данной статье представлен обзор, направленный на представление имеющейся информации о потенциальном экологическом воздействии микрочастиц пластика, возможных источниках и путях попадания в почвы, а также о предлагаемых методах аналитического контроля данного загрязнителя. Обзор позволяет наметить основные методологические проблемы, задачи и перспективы исследований в данной области.

The ubiquitous use of plastics has led to an increase in the amount of plastic debris that accumulates in the environment and breaks down into small fragments, including <5 mm microplastics. Over the past decade, an increasing amount of research has focused on the potential hazards and methods for analyzing plastic particles in the aquatic environment. However, soils can be much more heavily contaminated, and little is known about the accumulation of microplastics in soil, possible sources, consequences, interactions of plastic particles with soil organisms, and effective methods of analysis. This article provides an overview aimed at presenting the available information on the potential environmental impacts of microplastics, possible sources and routes of entry into soils, and proposed methods for the analytical control of this pollutant. The review allows to outline the main methodological problems, tasks and prospects for research in this area.
Case report of pulmonary embolism in pediatric practice
Authors: Belousova Tamara V. , Loskutova Svetlana A. , Zatolokina Anastasia O. , Plyushkin Valeriy A.
Published: September 2022

An analysis of the clinical situation of a 14-year-old patient with pulmonary embolism (PE) and current information on the risk factors for the development of thrombotic events are presented. Due to the presence of gynecological pathology, the girl was prescribed hormonal drugs, in particular, dydrogesterone and estrogen + gestagen. Against the background of its use, complaints of shortness of breath appeared, which was regarded as a manifestation of bronchial obstruction and bronchodilator therapy was prescribed. Due to the lack of positive dynamics during treatment, she was hospitalized. MSCT of the chest organs was performed: signs of PE were revealed; A molecular genetic study of the DNA of buccal epithelial cells (PCR) was carried out: the carriage of prothrombogenic polymorphic variants of genes of the hemostasis system was revealed, the most significant of which is a heterozygous mutation of the prothrombin FII gene (G20210A); the study of the hemostasis system revealed thrombinemia. In therapy, thrombolysis was not performed, low molecular weight heparins were prescribed the child's condition improved. The question of the need for a comprehensive examination, including research on the carriage of prothrombogenic polymorphic variants of the genes of the hemostasis system for pediatric patients in situations requiring the administration of hormonal drugs for a long course, to prevent the ocurrence of dangerous thrombotic complications, is discussed.
Constitutional delay of growth and puberty – features of the clinic and diagnosis: Prospective study
Authors: Filina Natalia Yu. , Cherednikova Kseniya A. , Bolotova Nina V. , Nikolaeva Nataliya V. , Novikova Elena P. , Petrova Mariia G. , Nesterenko Oksana V.
Published: September 2022

Aim. To assess clinical, hormonal and metabolic characteristics of adolescent boys with constitutional delay of growth and puberty.
Materials and methods. One hundred teenage boys aged 15 were examined. The main group (n=70) patients with constitutional delay of growth and puberty (inclusion criteria: height SDS -2.0 and below, Tanner 1); comparison group (n=30) healthy adolescents of the same age. Objective examination: height SDS score, BMI SDS, puberty score. Laboratory diagnostics: IGF-1, testosterone, luteinizing hormone, follicle-stimulating hormone, inhibin B, anti-Mullerian hormone; stimulating tests: clonidine test, triptorelin test. Instrumental methods: radiography of the bones of the wrist of the left hand with the wrist joint to assess bone age using the GreulichPyle method, ultrasound examination of the scrotum, assessment of the component composition of the body by bioimpedancemetry. Statistical data processing: XL Statistics version 7.0, Microsoft Excel, 2010. Nonparametric statistical methods were used. Data are presented as a median indicating the values of the 1st and 3rd quartiles ([Q1; Q3]), the MannWhitney test was used.
Results. Patients with constitutional delay of growth and puberty had significantly lower rates of physical development compared with healthy peers (p=0.003). Most patients of the main group were found to be underweight, accompanied by a persistent decrease in the proportion of active tissues and a significant, paradoxical increase in the proportion of fat mass according to bioimpedancemetry. The identified deviations indicated metabolic disorders and indicated the formation of sarcopenia syndrome in adolescents with CIGR. The level of sex hormones corresponded to the degree of biological immaturity of the patients, low values of inhibin B in combination with an increased level of AMH indicated Sertoli cell deficiency.
Conclusion. The pronounced deviations in the clinical, hormonal and metabolic status of patients with constitutional delay of growth and puberty obtained during the study were traced in the clinical picture of most adolescents, which is a significant deviation in the child's health and requires medical correction.
Carbohydrate and lipid metabolism in children after coronavirus disease: Observational study
Authors: Isaeva Elena P. , Zaytseva Olga V. , Lokshina Evelina Е. , Zaytseva Svetlana V. , Murtazaeva Olga A. , Okorokov Pavel L. , Zyabkin Ilya V.
Published: September 2022

Background. Six months after coronavirus disease (COVID-19), more than half of the children have various clinical manifestations of post-covid syndrome. In adult patients without a history of diabetes mellitus, cases of carbohydrate metabolism disorders against the background of COVID-19 and in the long term after the disease have been described. Coronavirus infection in adult patients with lipid disorders is associated with a high risk of severe COVID-19. A 12-year follow-up of patients with severe acute respiratory syndrome (SARS) caused by SARS-CoV showed that they were at an increased risk of developing dyslipidemia. For patients who have undergone SARS-CoV-2, there are no such data due to the short follow-up period. Studies in children evaluating the impact of coronavirus disease on the state of carbohydrate and lipid metabolism are isolated and contradictory.
Aim. To compare indicators of carbohydrate and lipid metabolism in children after a coronavirus disease with a control group of healthy peers without a history of COVID-19.
Materials and methods. The study included 108 children aged 3 to 17 years, divided into two groups. The study group included 50 children (mean age 12.0 [7.4; 14.5] years) after a coronavirus disease. The average follow-up period after the disease was 6 months (from 3 to 12 months). The control group consisted of 58 healthy peers (mean age 12.5 [7.5; 15.1] years) without a history of COVID-19. All children underwent an assessment of the level of glucose in the blood serum, lipid metabolism and the calculation of the triglyceride-glucose index (TyG index).
Results. The frequency of impaired fasting glycemia in children after a coronavirus disease was 2% and was comparable to the control group of healthy peers without a history of COVID-19. The TyG indices in the study groups did not differ significantly (4.46 [4.11; 4.65] vs 4.33 [4.0; 4.47]; p=0.37). None of the children included in the study showed an increase in the TyG index to values corresponding to the criterion of insulin resistance. An assessment of the state of lipid metabolism also did not reveal significant differences in the levels of total cholesterol, LDL, HDL and triglycerides, depending on the presence of a history of coronavirus disease.
Conclusion. In children six months (312 months) after coronavirus disease, there was no increase in the frequency of impaired fasting glycemia and insulin resistance compared to healthy peers without a history of COVID-19.
Breast milk oligosaccharides: what do we know today?
Authors: Zakharova Irina N. , Orobinskaia Iana V. , Sugian Narine G. , Kovtun Tatiana A. , Tabulovich Elena V.
Published: September 2022

Breastfeeding remains the "gold standard" for feeding babies in the first year of life. Breast milk contains a mixture of nutrients; their amount varies throughout the lactation period and even throughout the day. The composition of breast milk (BM) is complex and dynamic. Currently, BM oligosaccharides (BMOs) are of most interest to researchers. Due to advances in science and biotechnology, more than 200 BMOs have been identified. Human BM is the richest source of oligosaccharides among all mammals (for instance, their content in cow's milk is almost 1,000 times lower). Numerous favorable effects of BMOs on child health are related to the immune response, gut barrier function, and protection against pathogens. BMOs as prebiotics contribute to the formation of the infant's intestinal microbiome. The BM contains a complex bacterial community whose composition depends on the maternal microbiome (skin, gut, genital, urethral tracts) that forms the infant gut microbial community. In the absence of breastfeeding, modern formulas can be used; BMOs in their composition make them more like BM.
Building Collectives: Co-housers in Urban New Zealand
Authors:   , Pinchen Anna
Published: September 2022

Co-housing is a new mode of urban dwelling that is becoming increasingly prominent in New Zealand. In this thesis I engage with this emerging form of dwelling by exploring what motivates individuals and groups to create co-housing and describing what building collectives look like in an urban New Zealand context. I delve into the motivations, struggles, experiences, and design decisions of urban co-housers. In order to do this, I spent three months travelling to five different co-housing projects across Auckland, Wellington, and Christchurch. I conducted seven semi-structured ethnographic interviews with 12 participants, supplemented by blogs, site visits, websites, and my time at the CoHoHui conference in Wellington. Using these methods, I show that co-housing in urban New Zealand is a new mode of dwelling, which is emerging primarily as a response to three crises: loneliness and social isolation, un-affordable and inadequate housing, and the climate crisis. The way in which my participants responded to these crises can be observed throughout their journeys. These three crises are evident in co-housers motivation to create co-housing, their methods of working within and around New Zealand’s “developer landscape,” and how they physically designed their communities. My participants are rejecting the dominant typologies of urban housing in New Zealand, which they feel they do not adequately address these three crises. In doing so, they are creating alternative futures that they believe are economically, socially, and environmentally sustainable. While my participants do not always achieve everything they hope to, by creating alternative futures through new modes of urban dwelling, my participants are highlighting the fact that things can be different and showing us how these changes might be achieved.
Fundamentos del diseño en acero estructural
Authors: Pino Tarrago Julio Cesar , Villavicencio Cedeño Erik Gabriel , Gallegos Campos Christian German
Published: September 2022

Por medio de los estudios y análisis que presentamos a continuación pretendemos dar un enfoque general de las particularidades y propiedades de elementos estructurales presentes, principalmente en estructuras metálicas. En algunos de los casos se llega a profundizar más sobre el tema tratado, se analizan aspectos importantes como las generalidades de elementos sometidos a flexión, así como particularidades de columnas presentes en pórticos; estos temas se ven relacionados directamente con el diseño de estructuras de acero. Se tratará de explicar profundamente la parte teórica conceptual de su contenido, debido a que en la práctica es muy importante. Con este tipo de metodología se buscará contribuir favorablemente a la capacidad cognitiva y, por ende, brindar las adecuadas pautas para realizar un trabajo relacionado con estas temáticas. Manual de la construcción de acero del AISC Principalmente, utilizaremos y analizaremos el Código AISC (American Institute of Steel Construction) de 1993, el cual se basa en el diseño de acero por factores de carga y resistencia (LRFD). Para el correcto desarrollo de las temáticas usamos algunos textos básicos como consulta que tienen un alto valor académico, y como ayuda de diseño –muy importante–, se empleó el Manual de la construcción de acero del AISC. Queremos destacar que para el diseño de elementos de acero hay cuatro herramientas básicas: expresiones de diseño y revisión (método analítico “a mano”), tablas de diseño, cartas de diseño y software especializado. En la aplicación de cualquiera de ellos estamos en la obligación de conocer, con bastante grado de detalle, las bases de cálculo e hipótesis en que se fundamentan. Este curso tiene ese objetivo.
Manual metodológico para el desarrollo de capacitaciones a asociaciones productivas y pequeños emprendimientos
Authors: Herrera Velázquez María del Rosario , Córdova Castro Andrés Eduardo , Lucio Pillasagua Adela del Jesús , Baque Sánchez Erick Raúl , Álvarez Vásquez Carmen Argentina , Romero Castro Rosario Magdalena , Conforme Cedeño Gema Monserrate , Rivera Vera Humberto Fabricio
Published: September 2022

La presente guía ofrece un conjunto de pautas para realizar las actividades de capacitación. En el presente formato se usa una serie de símbolos con la intención de ofrecer a el/la facilitador/a una ayuda gráfica que facilite la presentación de la actividad. La siguiente es una lista de los símbolos utilizados. En el Ecuador, el sector de las microfinanzas ha venido creciendo y evolucionando notablemente, generando una fuerte competencia entre los actores dedicados a este segmento ya que se han desarrollado una gran cantidad de instituciones especializadas en estos servicios, principal-mente cooperativas, la importancia de estas instituciones radica en su contacto con grupos poblacionales de bajos ingresos que no poseen los requisitos que hasta hace poco exigía la banca tradicional, quienes miran en estas instituciones la posibilidad de recibir apoyo financiero para iniciar sus actividades económicas. Las microfinanzas tienen que ver con servicios financieros de consumo, transferencias de remesas, seguros, depó-sitos en cuentas de ahorro, tarjetas de débito, programas especiales de ahorro, crédito para adquisición de activos, crédito para la vivienda, pago de servicios e impuestos y otros servicios destinados a hogares con bajos ingresos que tradicionalmente no han tenido acceso al sistema financiero.
Modelo de gestión pública cantonal para la reactivación de la caficultura ecuatoriana sobre bases agroecológicas
Authors: Ponce Vaca Luciano Abelardo , Orellana Suarez Kleber Dionicio , Plama Ponce Richard , Fuentes Figueroa Tomas , Pionce Muñiz Paul
Published: September 2022

La gestión pública en Ecuador adquiere cada vez más relevancia, en términos de mejorar la calidad de la producción y los servicios en los distintos sectores socioeconómicos del país, en ese contexto es necesario potenciar la gestión pública desde los gobiernos autónomos descentralizados en función de reactivar la caficultura ecuatoriana. En esta obra se fundamentan los componentes y relaciones esenciales del modelo, así como el procedimiento para su implementación lo que permite articular acciones concretas para dar cumplimiento a la política cafetalera, potenciando a nivel cantonal, un proceso de gestión pública para la reactivación de la caficultura sobre bases agroecológicas. La gestión pública en Ecuador adquiere cada vez más relevancia en función de reactivar la caficultura ecuatoriana La aplicación del modelo de gestión pública constituye, desde la práctica social, la validación parcial del mismo, proceso en el cual, juegan un rol fundamental el gobierno autónomo descentralizado, los caficultores, las organizaciones de productores y los actores locales claves, vinculados a la actividad cafetalera, con lo cual, queda demostrado la viabilidad y factibilidad del modelo propuesto.
Infección Asociada a la Cirugía Digestiva
Authors: Vera Zambrano Christian Paul , Arteaga Intriago Miguel Ángel , Santana González Isidro Roberto , Loor Hidalgo Christopher Orley , Bravo Suarez Cesar Manuel , Cevallos Pablo Juan Manuel , Zambrano Intriago María Vanessa , Mora Vera Rina Victoria , Coello Vergara Jonathan Steven , Cedeño Casanova Agustina Elizabeth , Álava Bravo Erick Ismael , Pibaque Mero Fanny Margarita
Published: September 2022

La lucha contra la infección, y sus implicaciones nocivas para la salud de los seres humanos, es una de las tareas más antiguas del cirujano. Como es bien sabido, las infecciones quirúrgicas pueden dividirse, en aquellas que el cirujano opera, aquellas que constituyen el objeto de la intervención quirúrgica, y las que el cirujano produce, a raíz de la actividad o procedimientos quirúrgicos. Entre las primeras destacan las infecciones intraabdominales, como la peritonitis terciaria, la apendicitis aguda, la diverticulitis, la colecistitis aguda o las debidas a perforación de una víscera hueca. Las infecciones graves de las partes blandas y pared abdominal constituyen un grupo importante de la patología quirúrgica infecciosa en el que son protagonistas patógenos específicos. En realidad, la gran mayoría de las infecciones en cirugía digestiva están causadas por microorganismos del tracto digestivo o por bacterias exógenas procedentes del personal sanitario o del medio ambiente, asociados a una menor capacidad de defensa del huésped frente a la agresión quirúrgica. La otra parte importante de las infecciones en cirugía están relacionadas con la incisión quirúrgica, infección de la herida quirúrgica o dehiscencias anastomóticas. Son estas últimas las que el cirujano provoca en el paciente.
UMA PROPOSTA PARA ANÁLISE DE COMPONENTES PRINCIPAIS NA PRESENÇA DE VARIÁVEIS NÃO ALEATÓRIAS
Authors: GOMES Juliana Vieira , DIAS Camila Rafaela Gomes , RIBEIRO JUNIOR José Ivo
Published: September 2022

Para análise exploratória dos componentes principais (CPs), não é exigida a pressuposição de normalidade multivariada das variáveis e, nem necessariamente, que elas sejam aleatórias. Isso significa que variáveis que não se comportam aleatoriamente também podem ser incluídas nessa análise. Desse modo, a fim de realizar a análise dos CPs com variáveis aleatórias ou não, foi proposta uma correção da matriz baseada nos coeficientes de variação (Campana et al., 2010) por meio da aplicação do método de Lenth (1989), cuja nova matriz foi denominada. Para verificar a sua viabilidade, foram simulados dez conjuntos de dados das variáveis aleatórias Y1, Y2, Y3 e Y4, com 10.000 valores cada e que seguiram distribuição normal multivariada. Após a simulação, foram substituídos 0%, 1%, 2%, 3% e 4% dos valores aleatórios de Y4 pelos mesmos e respectivos percentuais de outliers, com o objetivo de quebrar a aleatoriedade da mesma. Posteriormente, foram realizadas análises de superfícies de respostas para oito diferentes erros percentuais médios absolutos obtidos em relação a oito parâmetros relacionados ao desempenho da análise dos CPs, em função dos percentuais de substituição por outliers de Y4 (0, 1, 2, 3 e 4) e das matrizes utilizadas na análise dos CPs. De acordo com os resultados, concluiu-se que, na presença de apenas variáveis aleatórias normais,  é a melhor matriz. Por outro lado, quando há a presença de outliers é a mais recomendada.
STOCHASTIC MODELING OF VEHICLE INSURANCE CLAIMS: AN APPLICATION IN THE SOUTH OF MINAS GERAIS/BRAZIL
Authors: PALA Luiz Otávio de Oliveira , CARVALHO Marcela de Marillac , SÁFADI Thelma
Published: September 2022

Risk and exposure factors are important features to be considered, providing financial and actuarial information for the insurer. Pricing methods aresupported by the mutualism theory, ensuring a level of indemnity and expected cost, making possible to constitute monetary reserves. The aim of our paper is to model and analyze the distribution of vehicle insurance claims in the south of Minas Gerais/Brazil. The data represents policies with a claim occurrence in the year of 2018. Under theBayesian approach, we consider the Gamma and Log-normal distributions that allow asymmetric data modeling and they can be used in loss models. The Jeffreys’s prior class was applied considering the data of the first semester of 2018. The information level was updated to construct an informative prior to analyze the data of the secondsemester. To compare models, we estimated the Bayes Factor and the logarithm of the marginal likelihood, that showed the Log-normal more likely. After selecting a model, we estimate metrics as the Conditional Tail Expectation (CTE) and the percentiles of the adjusted distribution to evaluate extreme costs. The results showed the applicabilityof Bayesian inference to fit insurance data, allowing to insert prior knowledge as the portfolio experience and to use a wide class of probability distributions.
THE ZERO, ONE AND ZERO-AND-ONE-INFLATED NEW UNIT-LINDLEY DISTRIBUTIONS
Authors: FERREIRA André Bisca , MAZUCHELI Josmar
Published: September 2022

In this paper, we propose the zero, one and zero-and-one-inflated New unit-Lindley distributions as natural extensions of the New unit-Lindley distribution to model continuous responses measured at the following intervals [0, 1), (0, 1] and [0, 1]. They were constructed based on convex combinations between the New unit-Lindley distribution and the distributions degenerate at zero, one, and Bernoulli distribution. They also have a number of interesting properties, such as being members of the exponential family. Besides, they have closed forms for the cumulative distribution functions, quantiles, and moments. Inferential aspects and regression structures arediscussed in this work as well as a Monte Carlo simulation study to evaluate theperformance of the regressors. Finally, we bring an application to real data on the suicide rate in the year 2016.
ANALYSIS OF MULTINOMIAL DATA WITH OVERDISPERSION DIAGNOSTICS AND APPLICATION
Authors: SALVADOR Maria Letícia , RIBEIRO JUNIOR Eduardo Elías , TACONELI César Augusto , LARA Idemaro Antonio Rodrigues
Published: September 2022

In agronomic experiments, the presence of polytomous variables is common, and the generalized logit model can be used to analyze these data. One of the characteristics of the generalized logit model is the assumption that the variance is a known function of the mean, and the observed variance is expected to be close to that assumed by the model. However, it is not uncommon for extra-multinomial variation to occur, due to the systematic observation of data that are more heterogeneous than the variance specified by the model, a phenomenon known as overdispersion. In this context, the present work discusses a diagnostic of overdispersion in multinomial data, with the proposal of a descriptive measure for this problem, as well as presenting a methodological alternative through the Dirichlet- multinomial model. The descriptivemeasure is evaluated through simulation, based on two particular scenarios. As a motivational study, we report an experiment applied to fruit growing, whose objective was to compare the flowering of adult plants of an orange tree, grafted on “Rangpur”lime or “Swingle” citrumelo, with as response variable the classification of branches into three categories: lateral flower, no flower or aborted flower, terminal flower. Through the proposed descriptive measure, evidence of overdispersion was verified, indicating that the generalized logit model may not be the most appropriate. Thus, as a methodological alternative, the Dirichlet-multinomial model was used. Compared to the generalized logit model, the Dirichlet-multinomial proved to be more suitable to fit the data with overdispersion, by allowing the inclusion of an additional parameter to accommodate the excessive extra-multinomial dispersion.
Entangled embodiment(s) with trauma: a play in six acts
Authors: Kelley Amber , Gale Jerry
Published: September 2022

Exposition
This play is about entangled embodiments of early career family therapists attending to clients’ trauma. It is drawn from research based on the theoretical framework of Karen Barad’s agential realism. As part of (2007) agential realism, the world is always already entangled and connected (Barad, 2007). I/we are not separate from one another, as in a murmuration, a shifting mass of starlings, thousands of birds flying together in dynamic shapes, shifting and moving in concert, responsive to one another and their larger environment (RSPB, 2022). In performing a murmuration, the birds cease to be distinct but instead are connected, communicating, and entangled as part of the larger form that is ever changing and becoming, allowing us to consider how thinking of systemic practice as a murmuration entails following lines of entanglement, connectedness, and iterative responsivity. To trace and track a murmuration, to learn from it and be a part of the embodied entanglement, is not to sit still, but to follow embodied shifts, to draw temporary and moving boundaries around the amorphous shapes and patterns that are forming/dissolving/re-forming in turn. Barad, a feminist quantum physicist (2007), refers to these boundary-drawing practices as agential cuts, or enactments that show what is inside/outside a phenomenon, not as inherently distinct, but as temporarily separated so the murmuration can be looked at, examined, and explored. This play is a series of agential cuts, six acts that together provide a broader narrative. This narrative weaves through/in/between the murmuration of systemic practice, exploring with curiosity what happens to the embodiments of systemic therapy practitioners when a client discloses a traumatic event or history. Based on Amber Kelley’s dissertation research, and presenting findings as poetry, this play follows an arc of exploration, an embodied journey through the entangled becomings of therapy practice and of being intimately with/in the trauma of our interconnected world.
Formation and Legal Principles of Lawyer in Turkey and Russia
Authors: Uzar Oğuzhan
Published: September 2022

Avukat hukuki sorunlarda görüş bildirmek,hukuki belgeleri düzenlemek, resmi dairelerde ihtilaflı işleri izlemek,mahkemeler ve hakem kurulları önünde gerçek ve tüzel kişilere ait hakları savunmak, yasaların ve hukuk kurallarının yargı
mercileri ve öteki resmimercilerce tam olarak uygulanmasına yardımcı olmak üzere hukukçuluk mesleğini yerine getiren” kimsedir. Avrupa ve Türkiye olarak iki farklı yanıt vermek gereklidir.Avukatlığın bugünkü haline gelmesine etken
olan hususlar, Avrupa kaynaklıdır.Avrupa’nın siyasal-sosyal kültürel hayatına baktığımızda avukatlığın meslek haline gelene kadar pek çok aşamadan geçtiğini görürüz.Savunma – hak arama mesleği olan avukatlık kimi yazarlara göre
Romaİmparatorluğu dönemiyle ortaya çıkmıştır.Bu çalışma ile farklı devletlerin ve medeniyetlerin huku ve avukarlık oluşumu ortaya çıkmakdatır.
Corporate Communication: A Conceptual Evaluation
Authors: Seyda Ozan Mehmet , Yolcu Faruk Selahattin
Published: September 2022

Günümüzde kurumların sürdürülebilirliklerini sağlayabilmeleri dinamik çevreye ayak uydurabilmesiyle alakalıdır. Bu çerçevede kurumların birer canlı organizma gibi hayatta kalabilmeleri ve sürdürülebilirliklerini sağlayabilmeleri proaktif
bir anlayışı gerekli kılmaktadır. Diğer yandan bu dinamik yapı potansiyel problemleri beraberinde getirebilmektedir. Bu kapsamda kurumsal işleyişte iletişim süreçlerinin efektif kullanımı konusunda sorunlar yaşanabilmektedir. Bu
doğrultuda gündeme gelen önemli kavramlardan biri kurumsal iletişimdir. Kurumsal iletişim kavramı; bir kurumun amaçlarına-hedeflerine ulaşabilmesi ve nihai olarak sürdürülebilirliğini sağlamasına adına gerçekleştirmiş olduğu iletişim
süreçlerinin bütünüdür. Bu süreç; kurum içi/dışı bilgi akışını, motivasyonel unsurları, eş güdümü, organizasyonel becerileri, eğitsel ve denetsel hususları içermektedir. Kurumsal iletişim aynı zamanda bir kurumun paydaşlarına ve
hedeflemiş olduğu kitleye karşı tüm iletişim kanallarını etkin bir şekilde açık tutması ile de tanımlanmaktadır. Tüm bu ifade edilenler kapsamında çalışmanın amacı temel bir bakış açısıyla kurumsal iletişim literatürünü incelemek
ve bazı önerilerde bulunmaktır
Perception and Support of the People of Eğirdir to the Slow City Model
Authors: Garda Betül
Published: September 2022

Günümüz toplumlarında küreselleşmenin bir sonucu olarak çeşitli dış faktörlerle etkileşime giren şehirler zamanla kendi öz kimliklerini kaybederek başta yörenin mimari dokusu ve yerel halkın kültürel özellikleri olmak üzere birçok
açıdan birbiriyle benzeşmeye başlamışlardır. Bu benzeşmenin turizm sektöründe getirebileceği olumsuz sonuçlara karşı sürdürülebilirliği sağlamak için bazı alternatif modeller ve kavramlar tartışılmaya ve uygulanmaya başlanmıştır.
Bu tartışmalarda kabul gören modellerin arasında, çevresel politikalarla uyumlu, yaşam kalitesini yükselten, sürdürülebilir bir şehir ağı olan ‘Yavaş Şehir’ modeli de bulunmaktadır. Ancak turistik destinasyonun farklılaştırılması
için tercih edilen alternatif turizm yaklaşımının, yerel halkın olumlu algısı ve desteği olmadan başarıya ulaşması mümkün değildir. Bu bağlamda çalışmanın amacı, Isparta’nın Eğirdir ilçesinde yaşayan yerel halkın “yavaş şehir”
olgusunu nasıl algıladıkları, destekleme biçimlerini ve ekonomik boyutuna ilişkin düşüncelerini incelemektir. Araştırma tanımlayıcı türde tasarlanarak, Eğirdir’de yerel yüzyüze uygulanan anketlerin incelenmesi sonucunda 150 geçerli
anket değerlendirilmiştir. Toplanan veriler sınıflandırılarak tanımlayıcı istatistikler, frekanslar ve çapraz tablolarda Ki kare, bağımsız örneklem t Testi, Tek yönlü varyans Analizi için Anova yöntemleri uygulanarak değerlendirilmiştir.
Araştırma sonuçları Eğirdir’de yerel halkın yavaş şehir konseptini genellikle olumlu algıladığını ve desteklediğini göstermektedir. Bu araştırma yerel halkın yavaş şehir algısının incelenmesinin önemini tekrar vurgulayarak diğer
turistik destinasyonlara ve gelecekte yapılacak olan çalışmalara örnek teşkil etmesi açısından değer taşımaktadır.
KLASIFIKASI TIGA GENUS IKAN KARANG MENGGUNAKAN CONVOLUTION NEURAL NETWORK
Authors: Ariawan Ishak
Published: September 2022

Ikan karang adalah salah satu organisme penting dalam kajian ekosistem terumbu karang, perlu dilakukan proses identifikasi untuk memahami pola, struktur dan distribusi keanekaragaman ikan karang. Selain itu, ikan karang memiliki jumlah yang sangat banyak dan hampir mirip satu sama lain. Oleh karena itu, untuk mempercepat proses identifikasi ikan dapat dilakukan secara komputerisasi. Salah satu teknik komputerisasi yang dapat dilakukan adalah pengolahan citra digital. Penelitian ini bertujuan untuk mengklasifikasikan citra genus Ikan (Epinephelus spp., Halichoeres spp., dan Lutjanus spp.) ekonomis penting. Data citra diperoleh dari situs https://www.kaggle.com/. Metode klasifikasi citra yang digunakan adalah Convolutional Neural Network (CNN) yang terdiri dari dua tahapan. Tahapan yang pertama adalah melakukan pelatihan dengan metode backpropagation, dan tahapan yang kedua adalah melakukan klasifikasi citra menggunakan feedforward. Hasil dari kombinasi dua metode tersebut diperoleh accuracy sebesar 85,31%. Selain itu, model yang dibangun cukup bagus karena selisih nilai rataan antara precision dan sensitivity tidak terlalu besar, precision sebesar 89,92% dan sensitivity sebesar 86,49%. Hasil analisis dan evaluasi yang telah dilakukan, dapat disimpulkan bahwa metode klasifikasi CNN dapat digunakan dengan baik dalam mengelompokkan citra Ikan berdasarkan genus.
IDENTIFIKASI FORMALIN PADA PRODUK HASIL PERIKANAN BAGI SISWA MADRASAH ALIYAH MIFTAHUL ULUM SUNGAI LUMPUR KABUPATEN OGAN KOMERING ILIR
Authors: Sofian Sofian , Yusanti Indah Anggraini , Jaya Fitra Mulia , Rochyani Neny , Utpalasari Rih Laksmi
Published: September 2022

Kecamatan Cengal Kabupaten Ogan Komering Ilir merupakan wilayah pesisir yang memiliki potensi perikanan yang cukup besar karena dikelilingi oleh perairan umum daratan dan pesisir laut. Akses lokasi yang sulit menyebabkan distribusi bahan baku perikanan ke luar wilayah menjadi kendala masyarakat mengingat masa simpan yang terbatas. Penggunaan bahan pengawet pada produk perikanan seperti formalin sering ditemukan dipasaran yang sangat berbahaya apabila dikonsumsi manusia secara terus menerus dalam jumlah sedikit. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk memberikan informasi kepada masyarakat melalui peran siswa serta guru Madrasah Aliyah Swasta Miftahul Ulum Sungai Lumpur tentang bahaya mengkonsumsi produk hasil perikanan yang mengandung bahan pengawet berbahaya seperti boraks dan formalin. Kegiatan ini dilaksanakan menggunakan metode pengujian secara langsung beberapa produk hasil perikanan yang melibatkan para siswa dan guru. Pengujian kandungan formalin dalam produk hasil perikanan secara sederhana dengan menggunakan tes kit formalin. Sampel uji dapat diamati secara langsung melalui perubahan warna hasil reaksi kimiawi sampel uji. Hasil kegiatan ini secara langsung menambah pengetahuan siswa tentang bahaya mengkonsumsi produk hasil perikanan yang mengandung bahan berbahaya bagi kesehatan. Selain itu, siswa dapat membedakan secara fisik produk hasil perikanan yang menggunakan bahan berbahaya serta dapat melakukan pengujian secara langsung kandungan berbahaya dalam produk hasil perikanan. Melalui kegiatan pengabdian ini masyarakat dapat mengurangi penggunaan bahan berbahaya sebagai pengawet makanan serta terhindar dari mengkonsumsi berbagai produk olahan hasil perikanan yang kurang sehat.
PELATIHAN PEMBUATAN MPASI DARI IKAN DI DESA PIJOT KECAMATAN KRUAK KABUPATEN LOMBOK TIMUR
Authors: Gigentika Soraya , Arianto Dika , Mustika Yuni , Bassok Novandita Esa Rakatama , Armadani Hendry , Hernanda Baiq Winda Larasati , Handriana Ika , Putri Helfiani , Nurhaliza Nirma , Julianfa Baiq Aminah
Published: September 2022

Persoalan stunting penting untuk diselesaikan karena berpotensi mengganggu potensi sumberdaya manusia dan berhubungan dengan tingkat kesehatan, bahkan kematian anak. Salah satu daerah di Indonesia yang perlu mendapatkan perhatian dalam permasalahan stunting adalah Desa Pijot yang berada di Kecamatan Keruak, Kabupaten Lombok Timur, Provinsi Nusa Tenggara Barat. Upaya yang dilakukan oleh Universitas Mataram dalam mencegah stunting di Desa Pijot adalah melibatkan mahasiswa KKN untuk melakukan pelatihan pembuatan MPASI dari ikan. Tujuan dari dilakukannya kegiatan pelatihan tersebut adalah untuk mengarahkan masyarakat agar dapat membuat MPASI dari bahan ikan laut dan memberikan pemahaman kepada masyarakat mengenai kandungan gizi dari ikan laut. Pelatihan pembuatan MPASI dari ikan menerapkan metode pembelajaran orang dewasa, sehingga pelatihan dilakukan dengan pendekatan aktif partisipatif, komunikasi dua arah, dan menggabungkan antara teori dan praktik. Target peserta pada pelatihan tersebut adalah kader Posyandu di Desa Pijot sebanyak 22 orang. Hasil dari dilakukannya kegiatan pelatihan pembuatan MPASI di Desa Pijot adalah perwakilan kader Posyandu yang hadir mendapatkan peningkatan pengetahuan atau keterampilan dalam pembuatan MPASI. Hal tersebut dibuktikan dengan berhasilnya mereka menghasilkan MPASI berbentuk bubur yang mengandung ikan laut. Selain itu, MPASI dari ikan yang dihasilkan juga memiliki tekstur dan rasa yang layak untuk bayi umur 6-24 bulan. Tidak ditemukan kendala yang berarti dalam pembuatan MPASI dari. Berdasarkan hasil pelatihan pembuatan MPASI dari ikan dapat disimpulkan bahwa potensi ikan laut di Desa Pijot dapat diolah menjadi MPASI untuk bayi umur 6-24 bulan karena ikan laut memiliki kandungan gizi yang sangat kaya untuk memenuhi kebutuhan gizi bayi sehingga dapat mencegah terjadinya stunting pada anak.
In vitro anticancer and antiproliferative activity of crocin on HCT-116 cells
Authors: Dogan Tuba  , Ozturk Serdar  , Apaydin Yildirim Betul
Published: September 2022

One of the world’s main causes of cancer-related fatalities worldwide is colorectal cancer. The adherent epithelial cells known as HCT116 (human colorectal carcinoma) are frequently employed to examine inflammatory responses in colonic epithelial cells. They are derived from the human colorectal cancer cell line. Crocin, a potent antioxidant, anticarcinogenic was tested in this study to see how it affected the HCT-116 human colorectal cancer cell line. MTT analysis was used to assess cell viability. Crocin's antiproliferative activity to inhibit the proliferation of HCT 116 cancer cells was examined. Crocin displayed the outstanding activities for MTT test, IC50= 10.57 μL/mL for 24 hours was calculated as IC50= 3.29 μL/mL for 48 hours on HCT 116 cell line. Total antioxidant status (TAS) and total oxidant status (TOS) in the prepared cell lysate were determined by using commercial kits. Crocin is thought to be a high potential agent to be used in treatment.
The effect of propolis-xenograft on the expression of SOX2, SOX9, and woven bone in alveolar bone remodeling
Authors: Utari Kresnoadi  , Jennifer Widjaja  , Primanda Nur Rahmania  , Muhammad Dimas Aditya Ari  , Imam Safari Azhar
Published: September 2022

Objective: This study was intended to analyze the expression of SRT-box transcription factor (SOX)2, SOX9 and woven bone in the preservation of tooth extraction sockets due to induction with propolis extract and bone graft. Materials and methods: 56 Cavia cobaya was divided into four groups according to the socket filling material used: control group, a propolis extract group, a bovine xenograft group, and a propolis extract-bovine xenograft group. An incisor tooth was extracted from each subject and the resulting socket filled with specific materials based on the group of which it was a member. After 3 days and 7 days, the Cavia cobaya were sacrificed in order to obtain their mandibles. Histopathological samples were made by means of hematoxylin-eosin and immunohistochemical staining under a light microscope at 400x magnification. Statistical analysis: The results were analyzed using one-way ANOVA. Results: A combination of propolis extract and bovine xenograft produced the highest expressions of SOX2, SOX9, and woven bone on day 3 and day 7, followed by the propolis group. The combination group experienced a significant difference with the control group on day 3 and day 7 (p<0.001). Even though the combination group presented the highest expressions, the results of a Tukey HSD test indicated no significant difference between the propolis and combination groups on day 3 and day 7. Conclusion: A combination of propolis and bovine xenograft increased the expressions of SOX2, SOX9, and woven bone. Further research is required to validate the bone remodeling acceleration hypothesis with regards to propolis.
Floating microspheres: Emerging delivery system for diabetes mellitus
Authors: Aman Shukla  , Deepika Joshi  , Bhavana Singh  , Nidhi Semwal
Published: September 2022

In order to increase bioavailability, stability, and target the drug to a specific region at a predetermined rate, floating microspheres, multi-unit drug delivery systems, are designed to accomplish controlled or delayed drug administration. In clinical practise, drugs that have an upper small intestine absorption window may benefit the most from a controlled drug delivery system with an extended stomach residence period. The non-uniformity of medication absorption throughout the gastrointestinal tract and the heterogeneity of gastrointestinal (GI) transit time across and among subjects are the two key issues. The most common drug delivery systems in these applications are floating or hydrodynamically controlled. Gastro retentive medication delivery is a method of extending the length of gastric residency because it targets site-specific drug release for local or systemic effects in the upper gastrointestinal tract (GIT). Due to the uniform distribution of these multiple-unit dose forms in the stomach, which encourages more repeatable medicine absorption and a lower risk of local discomfort, floating microspheres are becoming more and more popular. Compared to single-unit dosing variants, these systems offer more benefits. The physiology of stomach emptying is briefly examined in the context of floating drug delivery systems in this paper. This review's objective is to compile the most recent research on preparation techniques and other factors that affect the functionality and characterization of floating microspheres.
Bioequivalence study of two Esomeprazole40 mg MUPS tablets in healthy adult Bangladeshi human subjects
Authors: Sabrina Akter Tushi  , Nithon Chandra Sahana  , Uttom Kumar Bhowmik  , Alimur Reza  , Arifa Akram
Published: September 2022

Background: The primary objective of this study is to investigate the bioequivalence of two formulations (test& reference) of Esomeprazole 40 mg MUPS Tablet in healthy, adult human subjects. Method: In this study, a single dose, two-sequence, two-way crossover randomized design was used to investigate the bioequivalence under fasting conditions. 14 healthy volunteers received the two formulations over the course of two treatment days, each followed by a seven-day washout period. Following the administration of a single dose of 40 mg of each formulation, blood samples were taken at predetermined time points and subjected to a validated LC-MS/MS method for Esomeprazole concentration analysis. The plasma concentration-time profiles of both formulations were used to determine the pharmacokinetic parameters Cmax, AUC0-t, and AUC0-∞. Result: Pharmacokinetic parameters Cmax, AUC0-t, and AUC0-∞ did not show any statistically significant differences. The 90 % confidence intervals of Cmax, AUC0-t, and AUC0-∞ for Esomeprazole was found 89.35% (82.27-97.03%), 107.61% (99.78-116.05%), and 107.72 (99.87-116.20%) respectively which is within predetermined bioequivalence acceptance limits of 80 - 125 %. Conclusion: In terms of absorption rate and extent, the test product of Beximcopharmaceuticals has met the regulatory requirements for bioequivalence with the reference product Nexium MUPS.
Strategi Guru Dalam Meningkatkan Mutu Pembelajaran Alqur’an Hadits Kelas 4 Di Madrasah Ibtidaiyah Al-Musthofa Nusa Tunggal
Authors: Sutikno Muhammad , Sari Resti Septika
Published: September 2022

Tujuan penelitian ini adalah untuk menggambarkan bagaimana strategi guru dalam meningkatkan mutu pembelajaran Alqur’an Hadits kelas 4 di Madrasah Ibtidaiyah Al-Musthofa Nusa Tunggal. Penelitian ini menggunakan data kualititatif. Data penelitian diperoleh observasi, wawancara, dan dokumentasi. Teknik analisis data yang digunakan adalah dengan teknik kajian isi (content analysis) dan deskriptif kualitatif.  Teknik ini dilakukan dengan mengidentifikasi data yang diperoleh, diolah kemudian dianalisis secara konseptual. Hasil penelitian menunjukkan bahwa strategi yang digunakan dalam proses pembelajaran Alqur’an Hadits kelas 4 MI Al-Musthofa Nusa Tunggal. Guru menggunakan strategi pembelajaran tidak langsung / berpusat pada siswa. Dalam meningkatkan mutu pembelajaran Alqur’an Hadits yang dilaksanakan oleh guru mata pelajaran Alqur’an Hadits di kelas 4 MI Al-Musthofa Nusa Tunggal, yaitu pertama, seorang guru harus bisa membuat RPP, Kedua, guru harus mempunyai sikap profesional dan kreatifitas (kreatif, inovatif, aktif), Ketiga, kesadaran guru akan tujuan pembelajaran, Keempat, guru menganjurkan peserta didik untuk mempunyai sumber belajar lain selain LKS.
Meningkatkan Keterampilan Berbicara Siswa Melalui Teknik Debat
Authors: Tatik
Published: September 2022

Tujuan dari  penelitian  ini adalah untuk mendeskripsikan peningkatan keterampilan berbicara  siswa dengan menggunakan metode debat di kelas VI MIN 2 OKU Timur. Jenis penelitian adalah PTK,  pendekatan kualitatif dan kuantitatif.  Subjek penelitian  27 siswa kelas  VI MIN 2 OKU Timur. Perencanaan siklus I  memperoleh persentase  sebesar 82,14%, siklus II 92,85%. Pelaksanaan siklus I sebesar 81,25%, siklus II sebesar 95%. Keterampilan berbicara  pada siklus I 78,54%, siklus II  93,15%. Dengan demikian, metode debat  dapat  meningkatkan keterampilan berbicara siswa  kelas VI MIN 2 OKU Timur.
Penerapan Metode Bernyanyi Pada Anak-Anak Dalam Menghapal Huruf Hijaiyah Kecamatan Prabumulih Utara Kota Prabumulih
Authors: Ballianie Novia , Muis Abdul , Hamzah Amir
Published: September 2022

Program pengabdian kepada masyarakat dalam bentuk pendidikan ini atas dasar kerjasama mahasiswa Kuliah Kerja Nyata Universitas Islam Negeri Raden Fatah Palembang dengan kelurahan Anak Petai Kecamatan Prabumulih Utara Kota Prabumulih Provinsi Sumatera Selatan untuk memberikan pengajaran terkait penerapan metode bernyanyi pada anak-anak dalam menghapal huruf hijaiyah di kelurahan Anak Petai melalui Taman Pendidikan Al-Qur’an (TPA) yang berjumlah 20 murid. Penelitian ini dilatar belakangi kurangnya dalam pengenalan huruf hijaiyah yang disebabkan oleh pembelajaran yang monoton. Pengajar hanya menyebutkan huruf hijaiyah saja dan tidak dilengkapi dengan penggunaan metode, sehingga anak-anak kadang lupa dalam mengenali huruf tersebut.