bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical significance of p16INK4a and p53 and their involvement in penile cancer development. A literature review
Authors:   Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania,  Carol Davila University Emergency Military Hospital, Bucharest, Romania", Spînu Arsenie D. , Marcu Dragoș R. ,   Carol Davila University Emergency Military Hospital, Bucharest, Romania, Amza Radu A. ,   Carol Davila University Emergency Military Hospital, Bucharest, Romania, Iorga Daniel L. ,   Carol Davila University Emergency Military Hospital, Bucharest, Romania, Mischianu Dan ,   "“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania , Carol Davila University Emergency Military Hospital, Bucharest, Romania", Costache Raluca S. ,   "“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania , Carol Davila University Emergency Military Hospital, Bucharest, Romania", Costache Daniel O. ,   "“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania , Carol Davila University Emergency Military Hospital, Bucharest, Romania", Constantin Adrian ,   Surgery Department, “St Mary” Clinical Hospital, Bucharest, Romania
Published: December 2022

"Background: Human papillomavirus (HPV) E6 and E7 oncoproteins are vital for developing HPV induced penile carcinoma. The viral oncoproteins play a central role in oncogenesis by interacting with several cellular regulatory proteins, such as p16INK4a and p53. Many studies suggest that these proteins showed clinical utility in predicting nodal disease, cancer specific survival, overall survival and even tumor grade. Understanding the molecular mechanism involved in the carcinogenesis of penile cancer could offer biomarkers for disease progression, treatment response and potential targeted therapies; (2) Methods: This paper is a prospective study on a group of 100 patients who underwent prostate surgery during 2013 and 2014 in the Urology Clinic of “Carol Davila” Central Military Emergency University Hospital Bucharest. They were tested for HPV by PCR and IHC (p16) methods; (3) Results: 11 cases (22%) of HPV were found in the cluster of patients tested. PCR and P16 were the HPV diagnostic tests used. In order to determine the consistency of the 2 tests, the Cohen’s kappa coefficient was used at a p level < 0.05. The PCR method had a sensitivity of 81.8% and a specificity of 94.9%. The P16 method had a sensitivity of 63.6% and a specificity of 89.7%."
Medical and chemical efficacy of respiratory physiotherapy and Remdesivir in patients with COVID-19 pneumonia: A systematic review and meta-analysis
Authors:   Zahedan University of Medical Science (ZAUMS), Zahedan, Iran, Bahmani Alireza , Mollashahi Zahra ,   Department of Anesthesia, School of Allied Medical Science, Zabol University of Medical Sciences, Zabol, Iran, Shahkarami Negar ,   Master of Operating Room Technology Faculty, Member of Fasa University of Medical Sciences, Fasa, Iran, Delavar Elahe ,   Gonabad University of Medical Sciences, Iran, Esfahani Hooman ,   Department of Emergency Medicine, Shahrekord University of Medical Sciences, Ayatollah Kashani Hospital, Iran
Published: December 2022

"Evaluated efficacy of Respiratory Physiotherapy and Remdesivir on patients with COVID-19 pneumonia. In current systematic review and meta-analysis study, articles published January 2019 to December 1, 2021 were reviewed in the databases of PubMed, Scopus, Web of Science, and EBSCO. Risk ratio and mean differences with 95% confidence interval (CI), fixed effect model and Mantel–Haenszel or Inverse-variance formula were calculated. The Meta analysis have been evaluated with the statistical software Stata/MP v.16 (The fastest version of Stata). Mean differences of PaO2/FiO2 ratio at 6h after chest Respiratory Physiotherapy was (MD, 66 mmHg 95 % CI 64.71 mmHg, 67.28 mmHg; p=0.0007). Risk ratio of recovery rate between experimental and control group was 0.20 (RR, 0.20 95 % CI 0.15, 0.25) with high heterogeneity (I2 =78.84%; p=0.00). Risk ratio of mortality rate between experimental and control group was -0.34 (RR, -0.34 95 % CI -0.65, - 0.03) with low heterogeneity (I2<0%; p=0.51). Based on the findings of meta-analysis, Respiratory Physiotherapy can play an effective role in respiratory therapy and rehabilitation of patients admitted to the ICU with COVID-19. A meta-analysis showed that treatment with Remdesivir could increase the recovery rate, especially in the early days of COVID-19; also reduces the mortality rate."
New pathophysiological aspects in chronic venous disease
Authors:   ”Dunărea de Jos” University of Galați, Faculty of Medicine and Pharmacy, Department of Pharmaceutical Sciences, Galați, România, Manolache Nicuța , Stoleriu Gabriela ,   ”Dunărea de Jos” University of Galați, Faculty of Medicine and Pharmacy, Clinical Medical Department, Galați, România, Brănişteanu Daciana E. ,   ”Grigore T. Popa” University of Medicine and Pharmacy, Faculty of Medicine, IIIrd Medical Department, Iaşi, România, Robu Silvia ,   ”Dunărea de Jos” University of Galați, Faculty of Medicine and Pharmacy, Department of Pharmaceutical Sciences, Galați, România, Diaconu Camelia ,   ”Dunărea de Jos” University of Galați, Faculty of Medicine and Pharmacy, Department of Pharmaceutical Sciences, Galați, România, Costache Daniel O. ,   Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Published: December 2022

"Chronic venous disease has been pathology of great interest over time. With its large prevalence among the world population (10-33% adult woman and 10-20% of men) through profound socio-professional implications that affect the quality of life of patients, chronic venous disease is a real public health problem, being an important cause of morbidity and disability, a permanent area of research in the medical-pharmaceutical field. Special attention is now given to identifying the mechanisms and stages of disease development. From studies that have highlighted the importance of venous hypertension as an essential element in the development of the disease, to this day it has come up to demonstrating the fundamental role of the venous endothelium and glycocalyx in triggering and progressing of chronic venous disease. Biochemical, immunohistochemical, and functional investigations have allowed the evaluation of changes that occur in cellular metabolism and evidence of some immune-vascular factors responsible for vascular alterations in chronic venous disease: specialized receptors, adhesion molecules, cytokines, matrix and metalloproteinases. The analysis of the pathophysiology of chronic venous disease is still a vast area open to scientific research."
Risk factors for abdominal compartment syndrome in trauma – A review
Authors:   Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, Manole Ruxandra A.M. , Ion Daniel ,   Carol Davila University of Medicine and Pharmacy, Bucharest, Romania 2 3rd Department of General Surgery, University Emergency Hospital Bucharest, Romania, Bolocan Alexandra ,   Carol Davila University of Medicine and Pharmacy, Bucharest, Romania 2 3rd Department of General Surgery, University Emergency Hospital Bucharest, Romania, Păduraru Dan N. ,   Carol Davila University of Medicine and Pharmacy, Bucharest, Romania 2 3rd Department of General Surgery, University Emergency Hospital Bucharest, Romania, Andronic Octavian ,   Carol Davila University of Medicine and Pharmacy, Bucharest, Romania 2 3rd Department of General Surgery, University Emergency Hospital Bucharest, Romania
Published: December 2022

" Background and Aim: Abdominal compartment syndrome is a life-threatening complication that can occur in trauma patients and greatly increase their mortality. Although there is a better scientific understanding of the general phenomena involved in the pathogenesis of this complication, the particular risk factors and their implications in the trauma patient population are yet to be deciphered. Methods: The authors conducted research through 3 electronic databases (PubMed, Scopus, and ScienceDirect) using the following search formula: “(ACS OR abdominal compartment syndrome) AND (*trauma*) AND (risk factor)”. Subsequently, additional search formulas were used, including the risk factors taken into consideration (i.e. “shock”, “hypotension”, “acidosis”, “base deficit”, ”coagulopathy”, “retroperitoneal hematoma”, “HOB elevation”, “fluid resuscitation”, “damage control laparotomy”). Results: Throughout the 41 articles analyzed in this paper, 7 risk factors transcended and were further discussed: head of bed elevation/patient positioning, fluid resuscitation, the “lethal triad” of acidosis hypothermia and coagulopathy, Damage Control Laparotomy, shock/hypotension, retroperitoneal hematoma and demographics (age, gender, and race). Conclusions: To summarize, many potential risk factors were evaluated for the envisagement of the present paper, but the ones that prevailed the most were excessive fluid resuscitation, shock/hypotension, retroperitoneal hematomas, and the lethal triad. Consistent with other studies, no connection was found between age, gender, or race and the development of ACS. Further studies should focus more on the likely involvement of damage control laparotomy and patient positioning, as well as hypocalcemia, in the unfolding of ACS in trauma patients"
Retinal migraine, a contentious clinical entity
Authors:   ", Sirbu Carmen A. ,   Department of Neurology, ‘Dr. Carol Davila’ Central Military Emergency University Hospital, 134 Calea Plevnei, 010242, Bucharest, Romania", Nicolescu Vera M. ,   Department of Neurology, ‘Dr. Carol Davila’ Central Military Emergency University Hospital, 134 Calea Plevnei, 010242, Bucharest, Romania, Nițiș Ana O. ,   Department of Neurology, ‘Dr. Carol Davila’ Central Military Emergency University Hospital, 134 Calea Plevnei, 010242, Bucharest, Romania, Costache Raluca S. ,   Department of Internal medicine and Gastroenterology, Carol Davila University of Medicine and Pharmacy, 8 Eroii Sanitari Str, 050474, Bucharest, Romania, Ștefani Constantin ,   Department No. 5, University of Medicine and Pharmacy “Carol Davila”, 050474 Bucharest, Romania, Mitrică Marian ,   "Clinical Neurosciences Department, University of Medicine and Pharmacy ""Carol Davila"" Bucharest, 050474, Romania", Luncă Dragoș C. ,   Department No. 1, University of Medicine and Pharmacy “Carol Davila”, 050474 Bucharest, Romania, Anghel Daniela ,   Department of Medico Surgical and Prophylactic Disciplines, Faculty of Medicine, ‘Titu Maiorescu’ University, 031593 Bucharest, Romania
Published: December 2022

" Retinal migraine (ophthalmic migraine, ocular migraine, anterior visual pathway migraine) is a rarely encountered medical condition, but with an interesting and complex clinical presentation. The goal of this article is to compile the literature on retinal migraine, detailing nomenclature, pathophysiology, differential diagnosis, and medical investigations including newer imaging modalities, like optical coherence tomography (OCT). We will approach topics of great concern such as risk factors, complications, treatment, and management of this condition. Retinal migraine is mainly a diagnosis of exclusion and it must be isolated from transient monocular vision loss (TMVL) developed from other causes, for instance, papilledema, giant cell arteritis, carotid artery disease (amaurosis fugax), intermittent angle closure glaucoma, and others. Its treatment is similar to migraine treatment; topiramate, amitriptyline, and nortriptyline are some of the pharmacological drugs successfully used."
A Comparative Study on the Importance of Milk and Milk Products as a Complete Food
Authors: Pallathadka Harikumar , Pallathadka Laxmi Kirana , Manoharmayum Dolpriya Devi
Published: December 2022

Milk is a commonly consumed soft drink essential to many people's overall diet as it provides all crucial foods and micronutrients. Milk is considered valuable because it is synthesized before adolescence and adulthood. However, its relatively high soaked fat content raises the question of whether it can negatively affect the cardiovascular system. This study evaluates the latest publications on dairy products and human well-being, as described in epidemiological, academic, and biochemical evidence. For example, the effects of milk (especially skim milk) on body weight appear irrefutable, and the most famous studies show that the use of dairy products does not increase the incidence of cardiovascular problems or certain tumors. The study was conducted using a questionnaire and targeted two types of dairy products: packaged and unpackaged. The evidence is inconclusive, but some studies suggest that milk and its by-products may help some populations. Future studies will help clarify the role of milk and dairy products in human well-being, but their use in a proper diet should be considered without explicit contraindication fragments.
A Detailed Study of Space X Vs. Blue Origin Vs. Virgin Galactic and the Future of Space Travel
Authors: Pallathadka Harikumar , Pallathadka Laxmi Kirana
Published: December 2022

Space travel has had a generally short history. Regardless of its recency, the field has seen quick improvement in recent years. When the area of legislatures, space travel is currently likewise confidential. Starting from the primary business of human space flight occurred in 2001; a few other well-off space vacationers bought their rides into space. Over 150 individuals have pursued sub-orbital space trips with Virgin Galactic. Be that as it may, there are critical hindrances in making space travel a reality for the overall population. The enormous three Space X, Blue Origin, and Virgin Galactic are as yet developing confidential space industry was established entirely by super business visionaries who rose to acclaim (and significant riches) through non-space undertakings. Each has entered the ring with the usual point of reforming space travel, yet in light of one-of-a-kind goals and various dreams regarding how to accomplish their missions. Assuming that one property is shared by the administrations of SpaceX, Blue Origin, and Virgin Galactic, it is the definition of aggressive objectives. Here is a gander at the expressed missions of these three spearheading organizations: 1. SpaceX's central goal to make "humankind multi-planetary" is well in progress and has the red planet Mars soundly in its sights with the reusable Starship rocket program as the essential stage 2. Blue Origin additionally embraces rocket reusability as vital to its primary goal to save the planet by taking advantage of the room's "limitless assets and energy," comparing the new time of room travel and investigation to the Industrial Revolution of the cutting-edge period. 3. Virgin Galactic's main goal to "democratize space" will rely to a great extent upon the outcome of its space travel industry model by which the world's most memorable space line (rather than a carrier) will offer standard "flights" to space from its Spaceport America in New Mexico.
Herbal Essential Oil use as Ulcer Protective Activity: A Systematic Review
Authors: Chaudhary Harsh , Sagar Shivali , Kumar Roshan , Bisht Vijaylaxmi , Butola Kanchan
Published: December 2022

Around the course of the past few decades, essential oils have been an increasingly prominent subject of research all over the world. These naturally occurring chemicals may find applications in a wide variety of medical and biotechnological fields. In light of the urgent need to find new anti-ulcer agents and the significant amount of effort that has been put into developing medications for the treatment of ulcers, the purpose of this review is to investigate the anti-ulcer activities of fifteen different bioactive compounds that can be found in essential oils.
Conventional Cupping Therapy: Clinical Concerns
Authors:   *Department of Hematology, Faculty of Medical Laboratory Sciences, Port Sudan Ahlia College, Sudan., Bashir Bashir Abdrhman
Published: December 2022

Cupping therapy is a customary medical innovation for a great many years. It is a critical segment of reciprocal and alternative medicine in the universe as needle therapy. It is mainstream in numerous nations, particularly in China, Korea, Japan, Saudi Arabia, and even Sudan [1]. Cupping therapy can be employed in spacious curable disease, and a few enhancements in the technical research of cupping therapy has been Made [2]. More heeds are intensive on the adverse event statement and exhorted proposal or standard. Cupping therapy is compelling in numerous sorts of sicknesses. It is reported that Persian Cupping therapy can be applied in 1001 sorts of ailments. Latterly, cupping therapy is regularly exercising for pain, cardiovascular diseases, immune system anomalies and metabolic diseases, migraine, low back pain, fibromyalgia, shoulder pain, chronic non-specific neck pain, angina, arthritis, hypertension, ischemic and inflammatory myocardial disorders, herpes zoster infection, secondary amenorrhea, depression and anxiety, fatigue, and acne vulgaris [3].
The Association between Preoperative Anti-Tuberculosis Variability with the Resolution of Spondylitis Tuberculosis in Indonesia
Authors:   Department of Orthopedic and Traumatology, University of Indonesia, Indonesia., Lumban Singkat Dohar Apul Tobing , Wijaya Muhammad Triadi ,   Department of Orthopedic and Traumatology, University of Indonesia, Indonesia., Salamah Thariqah ,   Department of Radiology, University of Indonesia, Indonesia., Adhimulia Kevin Jonathan ,   Faculty of Medicine, University of Indonesia, Jl. Salemba Raya No.6, RW.5, Kenari, Kec. Senen, Kota Jakarta Pusat, Jakarta 10430,Indonesia., Mangasah Holong ,   Faculty of Medicine, University of Indonesia, Jl. Salemba Raya No.6, RW.5, Kenari, Kec. Senen, Kota Jakarta Pusat, Jakarta 10430,Indonesia., Susanto Budi ,   Faculty of Medicine, University of Indonesia, Jl. Salemba Raya No.6, RW.5, Kenari, Kec. Senen, Kota Jakarta Pusat, Jakarta 10430,Indonesia., Soraca Kanthi ,   Faculty of Medicine, University of Indonesia, Jl. Salemba Raya No.6, RW.5, Kenari, Kec. Senen, Kota Jakarta Pusat, Jakarta 10430,Indonesia.
Published: December 2022

Indonesia. Surgical management is indicated persistent symptoms despite the initiation of pharmacological treatment. Despite several studies that described preoperative administration of anti-tuberculosis drugs, there was no conclusion about the recommended duration and regiment to reduce the risks of complications.
Recurrent Perianal Squamous Cell Carcinoma in a Retroviral Patient
Authors:   Department of Surgery, Hospital Selayang, Selangor, Malaysia., Mohd Ussof Eskaandar Hussain , Muniandy Jothinathan ,   Department of Surgery, Hospital Selayang, Selangor, Malaysia., Henry Fitzjerald ,   Department of Surgery, Hospital Selayang, Selangor, Malaysia.
Published: December 2022

Anal squamous cell carcinoma is a cancer strongly associated among the immunocompromised and those infected with Human Papilloma Virus. We present a case of locally advanced recurrent anal cancer in a retroviral disease patient and the treatment planning involved in managing this patient.
Simulation removal of sulfamethazine, ciprofloxacin, sulfathiazole and amoxicillin via photo-Fenton process in by Monte Carlo modeling
Authors:   Department of Chemistry, Faculty of Science, University of Guilan P.O. Box 1914, Rasht 0098, Iran., Dezhampanah Hamid ,   Department of Chemistry, University Campus 2, University of Guilan, Rasht, Iran., Jalali Hamed Moradmand ,   Department of Chemistry, University Campus 2, University of Guilan, Rasht, Iran.
Published: December 2022

Kinetic Monte Carlo modeling was employed as a powerful tool to kinetically investigate of antibiotics removal by photo-Fenton process (iron(III) citrate/ hydrogen peroxide in the presence of UV irradiation). Sulfamethazine, ciprofloxacin, sulfathiazole and amoxicillin are the antibiotics which were studied in this investigation. The kinetic mechanism of the photo-Fenton degradation was found by Monte Carlo simulation for several studied antibiotics including sulfamethazine, ciprofloxacin, sulfathiazole and amoxicillin. Also the rate constants values of each step in the suggested mechanism were acquired for these antibiotics through the simulation. Optimized values of Fe(III) citrate and hydrogen peroxide were attained through obtaining the effect of their initial amounts on the rate of antibiotics elimination by utilizing kinetic Monte Carlo simulation. The perfect agreement is observed between the simulation results and the experimental photo-Fenton data for the systems above.
The Integrated Management of Cervical hyperostosis in Patients with Dyspnea and Dysphagia to Reduce Risk of Airway Compromise: A Case Series
Authors:   Department of Otolaryngology and Head and Neck Surgery, Albany Medical Center, Albany NY, USA., J Preece , Metkus James ,   Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, Stony Brook Medicine, Stony Brook NY, USA., V Shah ,   Albany Medical College, Albany NY USA, M Mortensen ,   Department of Otolaryngology and Head and Neck Surgery, Albany Medical Center, Albany NY, USA.
Published: December 2022

Diffuse idiopathic skeletal hyperostosis (DISH) is a non-inflammatory condition diagnosed by the presence of flowing vertebral ossifications along the anterior longitudinal ligament. Limited literature on cervical spine DISH, or cervical hyperostosis (CH), demonstrates that this sub-type of DISH may present with severe oropharyngeal symptoms. Two common manifestations of CH are dysphagia and dyspnea. The purpose of this case series was to provide more insight into detection and management of CH to potentially reduce the risk of impending airway compromise.
Research on Application of artificial Neural Network in econometrics
Authors: Sun Yike
Published: December 2022

As a fringe subject of artificial intelligence and systems engineering, artificial neuron network can not only discover more valuable data information, but also accelerate the calculation speed of data information in econometrics. With the rapid development of econometrics, the artificial neural network method has received wide attention of scholars research at home and abroad, compared with the traditional econometric method, artificial neural network algorithm with adjustable parameters and highly nonlinear simulation operation ability, self-learning and self-organization can function in dealing with practical problems, present a're likelier to carry a strong and adaptability. Therefore, on the basis of understanding the research status of econometrics and artificial neural networks, this paper mainly discusses how to apply artificial neural networks in econometrics, and makes clear the future application direction from the perspective of the development of the new era.
Research on regional landslide hazard warning model based on logistic regression
Authors: Zhang Yang , Liu Hui , Gu Chao , Zheng Yunmei
Published: December 2022

In the process of urban construction and development, landslide disaster is the main factor affecting the health and safety of local residents. How to put forward effective prevention and management measures according to the previous accumulated experience is the main problem of scientific research. Although the traditional regional geological disaster early warning model played an important role during the work, it did not comprehensively predict and analyze the regional landslide disaster and its impact due to the low prediction accuracy, insufficient application precision and insufficient data collection information. Nowadays, scientific researchers propose to use logistic regression algorithm for optimization and innovation in practice. The regional landslide disaster prediction model with logistic regression as the core can better meet the needs of practical research, master the geological disaster prediction information of the local area, and help the staff of the department to quickly develop solutions. Therefore, on the basis of understanding the application and research status of regional landslide disaster warning model, this paper deeply discusses the regional landslide disaster warning model with logistic regression algorithm as the core according to the basic principle of logistic regression algorithm. The final experimental results show that the prediction model has strong generalization ability and training accuracy.
Application technology of intelligent algorithm in civil engineering field
Authors: Wei Zixuan
Published: December 2022

In the development of modern urban construction, social residents of civil engineering quality requirements are more and more high, the traditional sense of the application of technology has been unable to meet the needs of the industry, how to reform and innovate the application of technology in the field of civil engineering, has become the main issue for enterprises to discuss. After entering the era of big data, intelligent algorithm has made excellent achievements in the research and application of various fields, especially in the field of civil engineering. The technical theoretical framework with intelligent algorithm as the core can not only collect and process more data information, but also improve the efficiency and quality of practical construction. Therefore, on the basis of understanding the research status of civil engineering application technology, this paper mainly discusses the application content of BIM technology, UAV mapping technology and GPS technology according to a variety of intelligent algorithms proposed in recent years, and determines the future development direction from the perspective of long-term development in the field of civil engineering.
“É FACA NA CAVEIRA”: A IDENTIDADE SIMBÓLICA DE TROPAS DE OPERAÇÕES POLICIAIS ESPECIAIS NO BRASIL
Authors: Gomes de França Fábio
Published: December 2022

O artigo demonstra, por meio de uma pesquisa teórico-bibliográfica, uma perspectiva histórica sobre como teria se desenvolvido o uso do símbolo da faca na caveira entre as tropas de operações especiais de Polícias Militares no Brasil. Para tanto, recorremos a fontes teóricas que discorrem sobre o surgimento do uso do símbolo da caveira com ossos cruzados desde o século XVII e como esse uso se desdobrou passando pelo período hitlerista na Alemanha até chegar ao Brasil, sendo utilizado por boa parte das Polícias Militares entre seus integrantes das tropas de operações especiais com o acréscimo de uma adaga encravada no crânio. Oobjetivo foi reconstruir esse contexto histórico para termos conhecimento sobre como se constituiu esse “mito moderno” acerca do símbolo da faca na caveira, dada a importância que ele adquiriu para os policiais militares que compõem os Batalhões de Operações Policiais Especiais (BOPE) em muitos estados brasileiros.
Reflexiones alrededor de las políticas públicas
Authors: Portela-Dussán Ángela Andrea
Published: December 2022

Objetivo: reflexionar acerca de algunos de los vicios o fallas que existen en los procesos abocados a las políticas públicas en el Distrito Capital. Fechas y lugares de la experiencia:  según el trabajo de asesoría y asistencia técnica realizado desde la Dirección de Planeación Sectorial de la Secretaría Distrital de Salud -SDS- de 2013 a 2019. Métodos: confrontación entre la perspectiva idealizada y abstracta de las políticas públicas en relación con el ejercicio práctico de las mismas, con base en la gestión y resultados obtenidos en el proceso de acompañamiento para el análisis, implementación y actualización de políticas públicas de la Secretaría Distrital de Salud. Resultados: los hallazgos se relacionan con la identificación conceptual alrededor de las políticas, que determina las formas y maneras en los instrumentos producidos; las dinámicas relacionales de poder, influencia, comunicación y empatía, que afecta el posicionamiento, la coordinación y la continuidad y los contextos organizacionales y políticos, que aseguran o no la estructura y recursos para actuar. Conclusiones: lo aprendido muestra que el andamiaje para las políticas públicas aún está en construcción y es necesario fortalecerse desde la innovación, la mejora continua, la investigación, la creación y la gestión de conocimiento.
Analysis of biomarkers for prediction of idiopathic infertility in Large White Yorkshire boar (Sus scrofa domesticus)
Authors: CHATTARAJ SOMRAJ , BASU SIDDHARTHA , RAY KALYANI , DATTA SANJOY , SARKAR PRADIP , MANDAL DURGADAS
Published: December 2022

The experiment was conducted to analyze biomarkers like pH, calcium (Ca2+), cholesterol (Ch), estradiol (E2) and vitamin D (Vit-D) in the serum for prediction of idiopathic infertility and its early amelioration. pH of epididymal luminal fluids (ELF) and concentrations of Ca2+, Ch, E2 and Vit-D were measured in serum, as well as in epididymal luminal fluids (ELF) and sperm cytosolic fluids (SCF) from caput, corpus and cauda epididymis of healthy, mature Large Yorkshire breed of boar (n=100). The levels of these bio-molecular components in the serum, in ELF and SCF from different epididymal segments were used statistically to develop a Curve Fit Regression Equations and a prediction equation to predict the quantum of these bio-molecules in the ELF and SCF by estimating their levels in the serum which would have been very difficult otherwise to be estimated in live animals. Further, from the clinical point of view, present findings about the spermatozoa maturation can pave the way for development of specific marker(s) that will assist in the development of new arena for both the prediction and early diagnosis of male infertility and for improving treatment modalities of male infertility, since epididymal dysfunctions are related to cases of idiopathic male infertility.
Effect of molasses based multi-nutrient herbal supplements on in vitro digestibility, serum enzymes and minerals profile in buffalo calves
Authors: KUMARI PUNITA , SINGH P , VERMA A K , GAUR G K , DAS A
Published: December 2022

Molasses based multinutrients herbal supplements (MMS) containing ground fenugreek seed and de-oiled mahua seed cake at two different ratios (1:1; MMS I or 1:3; MMS II) was evaluated under in vitro as well as in vivo conditions. For in vitro evaluation, concentrate mixture and wheat straw in 50: 50 ratio (on DM basis) was taken as substrate for the experiment. MMS I and MMS II were added at 2, 3 and 4% of the substrate, respectively. The total gas production (ml/g DM), partitioning factor (PF) and microbial biomass production (MBP) were found comparable in all the groups but significantly improved the IVDMD and IVOMD in supplemented groups. Under in vivo feeding trial, serum enzymes and minerals profile in buffalo calves were assessed during 9 months of experimental period. Fifteen male Murrah buffalo calves (10 to 15 months of age and mean body wt. 234.0±12.5 kg) were randomly distributed into 3 groups (5 in each group) according to randomized block design. All animals were fed with conventional concentrate mixture, available chopped green fodder (3-4 kg DM/d) and wheat straw ad lib to meet out nutrients requirement. While control group (C) were not fed supplements but groups T1 and T2 supplemented with MMS I and MMS II, respectively at 44 g/100 kg body weight or 200 g/100 kg metabolic body weight (kgW0.75). Serum AST, ALT activities and serum concentration of Ca, P, Fe, Mn, Cu and Co were comparable among 3 groups but serum concentration of Zn was significantly higher among supplemented groups. Thus, results show that supplementation of MMS improved IVDMD, IVOMD and serum Zn level resulting in to better health conditions of buffalo calves.
Effect of herbal feed additives containing saponins on rumen fermentation pattern
Authors: HUNDAL J S , WADHWA M , BAKSHI M P S
Published: December 2022

Macrotyloma uniflorum (kulthi) seeds, Asparagus racemosus (shatavari) roots or Acacia concina (shikakai) pods were supplemented to total mixed rations (TMR) @ 0-3% (on DM basis) to assess the impact of herbal feed additives (HFAs) on the in vitro rumen fermentation pattern. The saponin content and 2, 2-diphenyl-1-picrylhydrazyl- hydrate (DPHH) antioxidant activity was highest in A. racemosus than other HFAs. But total phenols, non tannin phenols, true tannins, condensed tannins, vitamin C and flavanoid contents were highest inM. uniflorum and lowest in A. concina. The dose/level of supplementation of HFAs, irrespective of their nature did not affect net gas production (NGP) and availability of metabolizable energy (ME) from TMR, but digestibility of nutrients and partitioning factor (PF) decreased in comparison to the unsupplemented group. The total and individual volatile fatty acids (VFAs) production; and acetate to propionate ratio was improved when the TMR was supplemented with HFAs at 1% level. The methane and ammonia-N production was depressed at 2% level as compared to control group. Irrespective of the dose, the total VFAs, acetate, and propionate production was higher while ammonia-N decreased in M. uniflorum supplemented TMR than other HFAs supplemented groups. Methane production from the TMR was comparable in the diet supplemented with different HFAs, however, diet supplemented with M. uniflorum resulted in lower methane production. Amongst the tested HFAs, M. uniflorum was a richer source of most of the bio-active compounds. Based on in vitro fermentation parameters, M. uniflorum supplemented to TMR @ 2% gave the best results.
Genetic and phenotypic trend for growth performance in Landlly pigs
Authors: NAHA B C , GAUR G K , SAINI B L , SAHOO N R , BORO P
Published: December 2022

This investigation aimed to evaluate the genetic parameters and trend for growth performance in Landlly pigs. Records of 2,118 piglets, born in 5 generations from 2013 to 2017 were analyzed for body weight at birth and subsequently at 1 week interval up to 8 week. There was a steady increase in body weight over the age from birth (0.96 kg) to 8 week (12.17 kg). The heritability estimate was low (0.112 to 0.129) for body weight at birth and 8 weeks, medium (0.156 to 0.290) for weight at 3 and 32 week and high (0.313 to 0.851) for other weights. Genetic trend was low and ranged from 0.001 (birth weight) to 0.041 kg (weight at 4 week). Phenotypic trend was positive, significant and higher than genetic trend (0.26 kg at birth to 3.36 kg at 8 week). The results showed that growth performance of Landlly pigs at this herd is improving in desired direction.
Comparative performance of Barbari goats under different rearing system in semi-arid region
Authors: SINGH M K , KUMAR RAVINDRA , SINGH S P
Published: December 2022

This study was undertaken to compare the performance of Barbari goats under grazing system and stall feeding system. Thirty growing Barbari goats of average body weight 15.20±0.54 kg of about 6 months of age were divided into three equal groups (Gr 1, Gr 2 and Gr 3) of ten animals each as per completely randomized design. The animals of Gr 1 was fed with concentrate pellet having 16% Crude protein (CP) while Gr 2 animals were fed with concentrate pellet having 18% crude protein. Goats of Gr 3 were fed with a combination of Concentrate pellet (16% CP), Gram straw, greens along with 6 h grazing. Total body weight gain was highest in Gr 2 followed by Gr 1 and Gr 3. Duration of experimental feeding was 192 days. Average daily gain (g) was 75.28 in Gr 1, 82.77 in Gr 2 and 65.14 in Gr 3. Average daily gain was highest in Gr 2 fed with high CP concentrate pellet and statistically similar to Gr 1 but significantly higher than the Gr 3 kept on grazing with supplementation of concentrate pellet, gram straw and greens. The blood Hb, RBC, PCV, WBC, lymphocyte, monocyte and granulocyte were comparable (P>0.05) among the different groups. Upon DLC analysis, different leukocytes were in the normal range in the stall fed group compared to the grazing group. However, plasma cortisol and testosterone level was significantly (P < 0.05) higher in Gr 3 compared to Gr 1 and Gr 2. But the concentrations of plasma cortisol and testosterone were similar in Gr 1 and Gr 2. Present study concluded that the performance of Barbari goats was better under stall feeding system and farmers can gain more profit in stall feeding system of goat rearing compared to grazing system.
Effect of accelerated ageing on viability and longevity of wheat (Triticum aestivum) seed
Authors: PATIL KALYANIRAO G , KARJULE AVINASH , PATEL D A , SASIDHARAN N
Published: December 2022

The accelerated ageing test (AAT) has been successfully used to rank and determine germinability of seed lots in various kind and varieties. An experiment was conducted to determine the influence of artificial ageing on seed viability and longevity of wheat seed of 2 varieties, viz. GW 496 and Lok 1. Progressive ageing period resulted in lowered seed quality in both wheat varieties. Combined effect of varieties and ageing duration showed the significant effect on all the observed seed quality parameters and recorded significant variation in these characters during (2015-16 and 2016-17) and in pooled analysis. The fresh seeds (without ageing) of wheat variety Lok 1 recorded highest average pooled germination (97. 50%), seedling vigour index I (2166), seedling vigour index II (20. 32) as well as observed biochemical parameters at the end of 5 days of accelerated ageing. Progressive ageing duration showed negative effect on biochemical parameters of the 5 days aged seeds of wheat variety GW 496 recorded lowest average pooled protein content (9.78%), carbohydrate content (60.36%), Î± amylase assay (6.19 micromoles/mg/min) and higher electrical conductivity (28.60 Î¼S/cm/g) due to fast deterioration at the end of artificial ageing.
Performance of groundnut (Arachis hypogaea) under different phosphorus management options in semi-arid environment of Rajasthan
Authors: YADAV M R , KUMAR YOGENDRA , POONIYA VIJAY , GUPTA K C , SAXENA RANI , GARG N K , SINGH AJEET
Published: December 2022

The present field investigation was carried out during kharif season of 2015, 2016 and 2017 at Rajasthan Agricultural Research Institute (RARI), Durgapura, Jaipur to evaluate the effect of various phosphorous (P) management options on growth, productivity and economics of groundnut (Arachis hypogaea L.). The experiment was carried out in a randomized complete block design with 10 P management practices. Results revealed application of 5 t farmyard manure (FYM) + 50% chemical P + DGRCâ€“1 and 5 t FYM + 100% chemical P + DGRCâ€“1 increased dry matter accumulation by 47.5% and 48.72% (35 days after sowing, DAS), 38.6% and 34.6% (70 DAS) and 38.9% and 35.1% (at harvest) over no P fertilization. Application of 5 t FYM + 50% chemical P + DGRCâ€“1 enhanced crop growth rate (CGR) by the magnitude of 19. 8%â€“47. 5% (0â€“35 DAS), 12. 5%â€“ 36. 3% (35â€“70 DAS), and 13. 4%5â€“39. 5% (70 DASâ€“at harvest) compared to control and 5 t FYM, 5 t FYM + DGRCâ€“1 and 5 t FYM + DGRCâ€“2 plots. The maximum number of pods/plant, pod weight/plant, test weight and shelling% were also registered with application of 5 t FYM +50% chemical P + DGRCâ€“1. With respect to yields, application of 5 t FYM + 50% chemical P + DGRCâ€“1 resulted in the maximum pod (5. 99 t/ha) and kernel (4. 29 t/ha) yields. The maximum net returns and B:C ratio were recorded when the crop was fertilized with 5 t FYM + 50% chemical P + DGRCâ€“1. Finally, it can be concluded that integrated P management in groundnut using 5 t FYM + 50% chemical P + DGRCâ€“1 can be advocated as sustainable P management strategy for enhancing productivity and profitability under semi-arid conditions of Rajasthan.
Validation of molecular markers for multiple disease resistance in tomato (Solanum lycopersicum)
Authors: HUSSAIN ZAKIR , LATA SUMAN , MANGAL MANISHA , TOMAR B S , YADAV R K , GOSAVI GOKUL , KUMAR ASHWANI , YADAV PAWAN , MONIKA MONIKA , YADAV S K
Published: December 2022

Marker assisted breeding has been successfully used for selecting disease resistance by identifying genetic markers linked to resistance genes/allele. In tomato, availability of molecular markers linked to genes conferring resilience against Tomato leaf curl virus (ToLCV) reaction, late blight, Tomato Mosaic Virus (ToMV) and Tomato gray leaf spot were utilised to develop pyramided MAS derived lines for multiple disease resistance. For this purpose, markers for the tomato leaf curl disease (ToLCD) resistance gene loci Ty-2, Ty-3 and Ty-3a, late blight resistant loci Ph-3, ToMV resistant allele Tm22 and Tomato gray leaf spot resistant gene Sm were validated using PCR assay. The assay correctly predicted the genotypes of tomato breeding lines harbouring resistant as well as susceptible alleles at each loci. Duplexing PCR assay combining two SCAR markers (T0302 and P6-25) for detecting simultaneously 3 important resistance gene loci (Ty-2, Ty-3 and Ty-3a) in tomato genotypes and thereby improving the cost efficiency of the PCR assay. Further, we have validated the Tomato leaf curl New Delhi virus (ToLCNDV) infection in tomato leaves by Reverse transcription (RT) PCR with ToLCNDV genome specific AC4 primers.
Physio-biochemical responses of hybrid citrus rootstock progenies to NaCl induced salinity
Authors: KALAL PRASHANT , SHARMA R M , DUBEY A K , KAMIL DEEBA , LEKSHMY S , KUMAR AMRENDER , AWASTHI O P
Published: December 2022

The study consisted 30 hybrids of Pummelo (P) Ã— Troyer (T) with two check cultivars, viz. Attani-2 and Troyer citrange, were subjected to 100 mM NaCl treatment through irrigations till the appearance of foliar symptoms. Of the 30 hybrids, only 3 hybrids, viz. P Ã— T-86, P Ã— T-98 and P Ã— T -102 showed higher photosynthetic rate (A) (6.22 -6.42 Î¼mol m2/s) than other hybrids. Furthermore, the level of O2 - was lowest in Attani-2. The lowest Cl- content was noticed in P Ã— T-102 (0.03%) followed by P Ã— T-98 (0.04%). Of the 30 hybrids (Pummelo Ã— Troyer citrange), evaluated against 100 mM NaCl induced salinity, 3 hybrids P Ã— T-86, P Ã— T-98 and P Ã— T-102 had very low scorching of leaves (32.88-33.15%), and were found tolerant as these hybrids expressed the low level of lipid peroxidation and Cl- accumulation in leaves, besides maintaining the higher A and MSI than other hybrids and Troyer citrange.
High density planting of potato (Solanum tuberosum) minitubers for increased seed productivity
Authors: KAUR RATNA PREETI , MINHAS JOGINDER SINGH , SINGH SUKHWINDER , SINGH AKHILESH KUMAR , SINGH RAJESH KUMAR
Published: December 2022

The experiment was designed to evaluate flatbed planting and density of early potato (Solanum tuberosum L.) seed generation of small minitubers produced under net house conditions of North-western plains. Two varieties Kufri Chandramukhi and Kufri Surya were used in the experiments conducted in 2015â€“17. The flatbed planting at different plant densities (30Ã—10, 20Ã—10, 15Ã—10 and 10Ã—10 cm) was compared with prevalent ridge and furrow method having 30Ã—10 cm row to row spacing as control in net house.Growth characters (plant height, number of leaves) along with yield parameters (yield, total number of tubers, undersize and seed size tubers) were evaluated for the treatments on per meter square basis. The spacing of 10Ã—10 cm on flat bed significantly outperformed the other treatments in yield as well as total number of tubers. On an average the flat bed planting at 10Ã—10 cm provided a benefit of twice the number of tubers and 1.4 times the yield over control ridge and furrow planting, yielding 259.74 tubers and 5.69 kg on per square metre area basis.The economics of this method was compared to the standard ridge and furrow method, where 1.7 times higher net profit was estimated. The adoption of flat bed planting in net house has tremendous potential in doubling the overall seed production and profitability, which would be itself favourable in advanced seed production generations.
Energy budgeting of crop-livestock-poultry integrated farming system in irrigated ecologies of eastern India
Authors: KUMAR SANJEEV , KUMAR RAVI , DEY AMITAVA
Published: December 2022

The purpose of this study was to determine energy input, output and energy use efficiency of an acre land based crop-livestock-poultry IFS model, developed at ICAR-Research Complex for Eastern Region, Patna during 2012â€“16. In the current investigation, total energy input in the experimental one-acre integrated farming model was calculated to be 45.08 GJ and total energy output obtained as 102.54 GJ, and resulted in energy use efficiency ratio as 2.27. Also, it was analysed that total energy input was required utmost for the goat rearing, i.e. 24.84 GJ/20 goats/year followed by field crops, vegetable, green fodders, fruits, poultry and mushroom cultivation. In the current IFS model labour, diesel and electrical energy inputs were required maximum in field crops. The direct and indirect energy sources were calculated and found to be invested utmost in field crops and goat rearing as 2.98 GJ and 24.53 GJ, respectively. Similarly, renewable and non-renewable energy sources were utilized in goat rearing and field crops as 24.39 GJ and 6.99 GJ, respectively. Moreover, energy use efficiency ratio was estimated highest in fodder crops (8.66) and lowest from goat rearing (0.17). It was found that goatry and poultry farming are of least energy efficient agricultural production systems, because they produced negative energy mileage. The energy use efficiency ratio for the main output has shown that green fodders and field crops yielded better energy productivity. The net energy gain was recorded maximum from field crops. The energy profitability analysis revealed that green foddersâ€™ cultivation was most profitable in terms of energy and produced EP ratio as 7.66 followed by field crops and vegetables, respectively.
Effect of organic nutrient sources on productivity, profitability and quality of ginger (Zingiber officinale) in acid soils of Eastern Himalayas
Authors: LEPCHA BONIFACE , AVASTHE RAVIKANT , SINGH RAGHAVENDRA , SINGH N J , PHUKAN PALLABI
Published: December 2022

Ginger cultivated with limited organic manures will produce low yields and would require different nutrient combinations for increased nutrition availability for higher productivity. The combination of organic nutrient sources was expected to increase and improve the growth and yield of ginger rhizome. Research experiments were conducted at Krishi Vigyan Kendra, Ranipool, East Sikkim, India to study the effect of different organic nutrient sources on yield and quality of ginger for three consecutive summer seasons (2013-15) under field conditions aimed to assess the effect of different combinations of organic sources on growth, yield, quality and profitability of ginger rhizome. The study revealed that a single organic soil nutrient source does not significantly influence the growth and yield of ginger rhizomes. The combination of two nutrient sources significantly influenced all parameters of the growth and yield of ginger rhizome. The combination of 50% pig manure + 50% poultry manure gave the best response to all the vegetative growth parameters, viz. plant height (109.0 cm), tillers per plant (16.3 nos.), number of leaves per tiller (17.9 nos.), size of leaves (30.9 cm2) but combination of 50% FYM + 50% rural compost showed the significant effect on finger length (39.3 cm), finger width (29.9 cm), finger weight (563.5 g), fresh yield (16.0 t/ha), cured rhizome yield (3.3 t/ha), net return (` 324.30 Ã— 103 ha) and benefit:cost ratio (3.0), oleoresin content (5.26%), essential oil (3.96%) and crude fibre (4.95%) in rhizome over the other treatment combinations.