bluuebunny/crossref_metadata_2025 huggingface dataset:
Research on Data Poisoning Attack against Smart Grid Cyber–Physical System Based on Edge Computing
Authors: Zhu Yanxu , Wen Hong , Zhao Runhui , Jiang Yixin , Liu Qiang , Zhang Peng
Published: May 2023

Data poisoning attack is a well-known attack against machine learning models, where malicious attackers contaminate the training data to manipulate critical models and predictive outcomes by masquerading as terminal devices. As this type of attack can be fatal to the operation of a smart grid, addressing data poisoning is of utmost importance. However, this attack requires solving an expensive two-level optimization problem, which can be challenging to implement in resource-constrained edge environments of the smart grid. To mitigate this issue, it is crucial to enhance efficiency and reduce the costs of the attack. This paper proposes an online data poisoning attack framework based on the online regression task model. The framework achieves the goal of manipulating the model by polluting the sample data stream that arrives at the cache incrementally. Furthermore, a point selection strategy based on sample loss is proposed in this framework. Compared to the traditional random point selection strategy, this strategy makes the attack more targeted, thereby enhancing the attack’s efficiency. Additionally, a batch-polluting strategy is proposed in this paper, which synchronously updates the poisoning points based on the direction of gradient ascent. This strategy reduces the number of iterations required for inner optimization and thus reduces the time overhead. Finally, multiple experiments are conducted to compare the proposed method with the baseline method, and the evaluation index of loss over time is proposed to demonstrate the effectiveness of the method. The results show that the proposed method outperforms the existing baseline method in both attack effectiveness and overhead.
Game-Theoretic Models of Coopetition in Cournot Oligopoly
Authors: Ougolnitsky Guennady , Korolev Alexey
Published: May 2023

Coopetition means that in economic interactions, both competition and cooperation are presented in the same time. We built and investigated analytically and numerically game theoretic models of coopetition in normal form and in the form of characteristic function. The basic model in normal form reflects competition between firms in Cournot oligopoly and their cooperation in mutually profitable activities such as marketing, R&D, and environmental protection. Each firm divides its resource between competition and cooperation. In the model in normal form we study Nash and Stackelberg settings and compare the results. In cooperative setting we consider Neumann–Morgenstern, Petrosyan–Zaccour, and Gromova–Petrosyan versions of characteristic functions and calculate the respective Shapley values. The payoffs in all cases are compared, and the respective conclusions about the relative efficiency of different ways of organization for separate agents and the whole society are made.
Agent-Based Collaborative Random Search for Hyperparameter Tuning and Global Function Optimization
Authors: Esmaeili Ahmad , Ghorrati Zahra , Matson Eric T.
Published: May 2023

Hyperparameter optimization is one of the most tedious yet crucial steps in training machine learning models. There are numerous methods for this vital model-building stage, ranging from domain-specific manual tuning guidelines suggested by the oracles to the utilization of general purpose black-box optimization techniques. This paper proposes an agent-based collaborative technique for finding near-optimal values for any arbitrary set of hyperparameters (or decision variables) in a machine learning model (or a black-box function optimization problem). The developed method forms a hierarchical agent-based architecture for the distribution of the searching operations at different dimensions and employs a cooperative searching procedure based on an adaptive width-based random sampling technique to locate the optima. The behavior of the presented model, specifically against changes in its design parameters, is investigated in both machine learning and global function optimization applications, and its performance is compared with that of two randomized tuning strategies that are commonly used in practice. Moreover, we have compared the performance of the proposed approach against particle swarm optimization (PSO) and simulated annealing (SA) methods in function optimization to provide additional insights into its exploration in the search space. According to the empirical results, the proposed model outperformed the compared random-based methods in almost all tasks conducted, notably in a higher number of dimensions and in the presence of limited on-device computational resources.
A Review on Per- and Polyfluoroalkyl Substances in Pregnant Women: Maternal Exposure, Placental Transfer, and Relevant Model Simulation
Authors: Wu Yuqing , Bao Jia , Liu Yang , Wang Xin , Qu Wene
Published: May 2023

Per- and polyfluoroalkyl substances (PFASs) are important and ubiquitous environmental contaminants worldwide. These novel contaminants can enter human bodies via various pathways, subsequently posing risks to the ecosystem and human health. The exposure of pregnant women to PFASs might pose risks to the health of mothers and the growth and development of fetuses. However, little information is available about the placental transfer of PFASs from mothers to fetuses and the related mechanisms through model simulation. In the present study, based upon a review of previously published literature, we initially summarized the exposure pathways of PFASs in pregnant women, factors affecting the efficiency of placental transfer, and mechanisms associated with placental transfer; outlined simulation analysis approaches using molecular docking and machine learning to reveal the mechanisms of placental transfer; and finally highlighted future research emphases that need to be focused on. Consequently, it was notable that the binding of PFASs to proteins during placental transfer could be simulated by molecular docking and that the placental transfer efficiency of PFASs could also be predicted by machine learning. Therefore, future research on the maternal–fetal transfer mechanisms of PFASs with the benefit of simulation analysis approaches is warranted to provide a scientific basis for the health effects of PFASs on newborns.
Engaging the Private Health Service Delivery Sector for TB Care in India—Miles to Go!
Authors: Suseela Rakesh P. , Shannawaz Mohd
Published: May 2023

More than half of the people with TB in India seek care from the private sector, where suboptimal quality of care is a concern. Significant progress has been made over the last five years to expand the coverage and to involve more private sector providers in TB care under the National TB Elimination Program (NTEP) in India. The objective of this review is to describe the major efforts and the progress made with regard to the engagement of the ‘for-profit’ private health service delivery sector for TB care in India, to critically discuss this, and to suggest the way forward. We described the recent efforts by the NTEP for private sector engagement based on the literature, including strategy documents, guidelines, annual reports, evaluation studies, and critically looked at the strategies against the vision of partnership. The NTEP has taken a variety of approaches, including education, regulation, provision of cost-free TB services, incentives, and partnership schemes to engage the private sector. As a result of all these interventions, private sector contribution has increased substantially, including TB notification, follow-up, and treatment success. However, these still fall short of achieving the set targets. Strategies were focused more towards the purchase of services rather than creating sustainable partnerships. There are no major strategies to engage the diverse set of providers, including informal health care providers and chemists, who are the first point of contact for a significant number of people with TB. India needs an integrated private sector engagement policy focusing on ensuring standards of TB care for every citizen. The NTEP should adopt an approach specifically tailored to the various categories of providers. For meaningful inclusion of the private sector, it is also essential to build understanding and generate data intelligence for better decision making, strengthen the platforms for engagement, and expand the social insurance coverage.
Bacteriostatic Effects of Yujin Powder and Its Components on Clinical Isolation of Multidrug-Resistant Avian Pathogenic Escherichia coli
Authors: Meng Jinwu , Wang Jinli , Zhu Jinyue , Li Siya , Qiu Tianxin , Wang Weiran , Ding Jinxue , Wang Wenjia , Liu Jiaguo
Published: May 2023

Escherichia coli is one of the most common pathogenic bacteria in diarrheal chickens, leading to serious economic losses in the poultry industry. The limited effect of antibiotics on antibiotic-resistant E. coli makes this bacterium a potential threat to human health. Yujin powder (YJP) has been reported as an agent that releases the symptoms caused by E. coli for a long time. The objective of this study is to investigate the effect of Yujin powder (YJP) and its components, Scutellariae Radix (SR) and Baicalin (Bac), anti-against multi-drug-resistant E. coli in vitro and in vivo. A multi-drug-resistant bacteria was isolated and identified from a clinical diarrheal chick. Then, the anti-bacterial effects of drugs were assessed in vitro and in vivo by analyzing the bacteria loads of organs, the levels of endotoxin, TNF-α, IL-1β, and IL-6 of the serum. Results found that the pathogenic E. coli was resistant to 19 tested antibiotics. YJP, SR, and Bac could directly inhibit the growth of this strain at high concentrations in vitro, and presents obvious anti-bacterial effects by reducing the bacterial loads, the release of endotoxin, and inflammation in vivo, which was much more effective than the resistant antibiotic ciprofloxacin. This study demonstrates that those natural medicines have the potential to be used as novel treatments to treat the disease caused by this isolated MDREC strain.
Interpretation of thesaurus in the sciences of culture and society
Authors:   Institute of Construction, Housing and Public Utilities, National Research University — Higher School of Economics (HSE University), Russian Federation, Grigorieva Irina Andreevna
Published: May 2023

The article is devoted to the methodology of cultural research. It is revealed that the concept of thesaurus in cultural studies, philology, and anthropology does not coincide with those accepted in linguistics and computer science. The author shows that the concept of thesaurus in cultural studies corresponds to the idea of a certain reserve, wealth, which can be called a treasure (from the Greek “thesaurus” — treasure, treasury). In other words, we can talk about the richness of language, knowledge, life experience, and so on. The author relies on the concept by Vl. A. Lukov and V.A. Lukov, who argue that the purpose of the concept of "thesaurus" appears when it is necessary to reflect the completeness of some knowledge that is essential for a given subject for some reason. The article highlights two main characteristics of the thesaurus: the first one is that we are speaking about the completeness/sufficiency of information, without taking into account its volume and measure; the second one is that the materiality of this knowledge is determined by the subject himself — his values, goals, attitudes, etc.
Modern musical culture in a transition state
Authors:   Moscow University for the Humanities, Shcheglova Tatyana Gennadievna
Published: May 2023

The article discusses the transitional type of culture, its systemic entry into the general global processes of society, and a new stage in the development of modern musical culture, which contributes to the interaction of musical art with other types of art, the synthesis of musical trends and styles and their impact on the processes taking place in modern society. In modern musical culture, new aspects of understanding culture and art associated with informatization processes have appeared. Media culture and the possibility of its development are closely related to the technical capabilities of storing and spreading information. The latest information technologies, instant transmission of new technologies, and art adaptation to the social processes taking place in society contribute to the dominance of mass culture in the social space, the active spread of "intermediate" trends in art, and the synthesis of mass culture with traditional and elite genres. The author shows that these phenomena can be used to attract the interest of young people to the traditional values and history of our culture, presented at a new, technological level.
PREVALÊNCIA DOS CASOS DA DOENÇA DE CHAGAS AGUDA NO ESTADO DO PARÁ EM 2018
Authors: Ferreira Lucas Araújo
Published: May 2023

Objetivo: O presente estudo visou identificar a prevalência dos casos de DCA no Estado do Pará e a relação com o consumo de açaí. Método: O presente trabalho é um estudo descritivo, retrospectivo, transversal, com abordagem quantitativa que utilizou dados secundários dos casos confirmados de Doença de Chagas Aguda no Estado do Pará no ano de 2018, onde os registros foram coletados no Sistema de Informação de Agravos de Notificação (SINAN) disponível no banco de dados públicos do Departamento de Informática do Sistema Único de Saúde (DATASUS). Resultados: Durante o ano de 2018, foram registrados 278 casos de Doença de Chagas Aguda no Estado do Pará, sendo os 3 meses com maior número de casos notificados os meses de Julho (44), Setembro (43) e Outubro (41). Conclusão: O consumo do açaí processado de forma incorreta continua a ser um dos principais transmissores da DCA no Estado do Pará.
Systems engineering of cybersecured digital and information measuring systems based on the signature Boolean-polynomial algebra synthesis apparatus
Authors: Tupkalo Viltalii , Cherepkov Serhii
Published: May 2023

Development of DIMSCC models with cyber-controllability of their apparatus and software for computing function (operations) in real time becomes the primary task since the problem relevance of the cyber security of digital information and measuring systems of control complexes (DIMSCC) for critical infrastructure objects is increasing. Based on an analysis of known digital systems functional control methods new term «functional cyber-controllability of the digital informational and measuring system» was defined in the article. New approach to operational functional control of hardware redundancy is proposed. This is the synthesis of DIMSCC computing operations. Hardware redundancy is a synthesized control node chosen for functional control of various DIMSCC basic arithmetic and logical functions (operations) which should be reduced to simple procedure of corresponding switching functionally complete combinational structures from a finite set (standard set). Concerning this, the synthesis task is as follows. Only inputs and outputs of specified object are available for functional control of arithmetic and logical operations on binary operands under external hacker influence. Combination type functional control node structure (operational compositional adaptation) should be developed depending on the type of controlled computing operation being performed. The result of the synthesis task solving is a system of formulae determination (signature control equations) of the signature functional control of all DIMSCC basic arithmetic and logical functions (operations) on a single basis of a single equivalent representation of their known formulaic expression by corresponding (adequate) descriptions in infix notation (infix models). Apparatus of Boolean-polynomial algebra is used aiming to realize infix notation. The practical advantage of the proposed approach to the synthesis of hardware redundancy of operational functional signature control of computing operations is the transition possibility from signature control equations formulae to their realization implementation in the form of a signature control node directly without additional interpreting and minimizing procedures use by simple logical composition (switching) functionally complete combinational structures from a finite set (standard set).
Проблеми метрологічної діяльності у сфері охорони здоров’я
Authors: Чижик І. В. , Сушко Л. Г.
Published: May 2023

Розглядаються питання, пов’язані із забезпеченням єдності вимірювань у сфері охорони здоров’я, відповідності метрологічної діяльності у зазначеній сфері вимогам чинного законодавства у сфері метрології.

Розглядаються вимоги керівних документів Міністерства охорони здоров’я України, що регламентують шляхи впровадження системи менеджменту якості та забезпечення єдності вимірювань в медичних лабораторіях, та стан їх впровадження.

Зазначаються проблеми, пов’язані з методичним забезпеченням лабораторних досліджень у сфері охорони здоров’я, відсутністю метрологічних вимог до процедур (методик) лабораторних досліджень, метрологічним підтверджуванням засобів вимірювальної техніки медичного призначення.

В статті також зазначаються проблеми, пов’язані з акредитацією медичних лабораторій відповідно до вимог ДСТУ EN ISO 15189 [1].
Diagnóstico de emprendimientos de economía popular y solidaria del cantón Cañar
Authors: Andrade Ortiz Carlos Israel , Ordóñez Laso Ana Luisa del Rocío
Published: May 2023

A pesar que los emprendimientos son un puntal en el desarrollo de los países, su horizonte resulta incierto por todos los problemas que deben enfrentar para alcanzar un posicionamiento o sostenibilidad. Este estudio tiene como objetivo realizar un diagnóstico de Emprendimientos de la Economía Popular y Solidaria (EPS) en el cantón Cañar, Ecuador. La metodología se basó en un enfoque cuantitativo de nivel descriptivo, para la recolección de la información se usó un cuestionario con 25 preguntas, previamente validado a 67 emprendimientos. Los resultados mostraron que los emprendimientos tienen una organización definida, el 74% de los emprendimientos están constituidas por más de un año; el 27% ha recibidos créditos, de los cuales el 83% provienen de cooperativas de la EPS, las necesidades en los emprendimientos son de capacitación y en áreas administrativas. Concluyendo que el diagnostico empresarial brinda información del contexto externo e interno necesario para tomar decisiones estratégicas que permiten el mejoramiento de las organizaciones.
Factores que condicionan la implementación de emprendimientos a partir de proyectos de educación media
Authors: Verdugo Orbe Evelin Danitza , Ordoñez Espinoza Cristina Guadalupe
Published: May 2023

El emprendimiento actualmente hace parte de las agendas gubernamentales y académicas, debido a la capacidad que tiene para impulsar el desarrollo y la innovación de las naciones. El objetivo de este estudio es determinar los factores que condicionan la implementación de emprendimientos a partir de proyectos de Bachillerato General Unificado. Se basa en una investigación de enfoque cuantitativo y nivel descriptivo, cuya recolección de datos se realizó mediante la técnica de la encuesta compuesta por un cuestionario Ad-hoc unitransversal donde la información se obtuvo de una única muestra conformada por 99 estudiantes y 5 docentes responsables del área de emprendimiento en el período lectivo 2022-2023 en instituciones educativas pertenecientes a la provincia de Cañar. Los resultados mostraron que aproximadamente cuatro proyectos se ponen en marcha anualmente luego de que los estudiantes se gradúan. Como conclusión se tiene que, el factor que mayor influencia es la falta de recursos económicos y la falta de apoyo institucional.
Tutoría académica: Competencias digitales de los docentes de educación superior en pandemia
Authors: Poma García Claudia Rossana , Rodríguez Aburto César Augusto , Poma García Jorge Luis , Sevilla Sánchez Regina Ysabel
Published: May 2023

A causa del COVID-19, las universidades tuvieron que adaptarse a la nueva metodología de la enseñanza virtual, implementándose las TIC, teniendo como objetivo general la interpretación del ¿cómo? y ¿cuáles? son las competencias digitales en la gestión educativa de la educación superior universitaria; la investigación es de nivel interpretativo, de enfoque cualitativo, con diseño hermenéutico, se efectuó entrevistas a cinco informantes clave, obteniendo como resultado que las estrategias predisponen el aprendizaje significativo a través del dominio de las TIC y el buen empleo del internet. Se concluyó replantear la destreza pedagógica, la capacidad tecnológica y la habilidad de la información para adecuarlos al confinamiento obligatorio por la presencia del COVID-19 a nivel global, del mismo modo el gobierno en respuesta debe tomar acción inmediata para que los habitantes tengan acceso a dispositivos tecnológicos con internet para continuar con la educación virtual.
Mediación tecnológica como estrategia pedagógica virtual
Authors: Mamani Ticona María Isabel , Zubiaur Alejos Miguel Angel , Sánchez Panduro Jessenia Choy , Orihuela Flores Jonathan
Published: May 2023

La crisis mundial del coronavirus ha dado lugar a importantes cambios sociales, políticos y económicos, que han abierto nuevas oportunidades para el desarrollo de las tecnologías de la información y la comunicación (TIC). El objetivo fue interpretar el uso de la tecnología como estrategia pedagógica por parte de los docentes en la educación virtual. El estudio tuvo enfoque cualitativo, diseño hermenéutico a nivel interpretativo; la técnica utilizada fue una guía de entrevista semiestructurada. Los hallazgos y la discusión permitieron determinar el uso de las TIC como estrategia por parte de docentes y administradores para facilitar el trabajo en el proceso de enseñanza y aprendizaje (PEyA). Finalmente, la interpretación fue que, los procesos deben entenderse como la gestión del conocimiento tecnológico, los recursos que benefician la educación y el aprendizaje, los desafíos en innovación y creatividad, la gestión del desarrollo de herramientas tecnológicas y la construcción de resultados de aprendizaje significativos.
Sobre o indivíduo fragmentado
Authors: Gebara Thiago
Published: May 2023

O presente ensaio busca tecer breves considerações sobre o indivíduo fragmentado, que se encontra na modernidade tardia e sofre de novos tipos de alienação. A tese da aceleração social de Hartmut Rosa será central na análise, bem como a utilização de outros autores e recursos que possam iluminar algumas das novas questões socias que surgem a partir do final do século XX e começo do século XXI. A hipótese sustentada é que a promessa do início da modernidade, da autonomia do indivíduo, e o progresso tecnológico e suas possibilidades para libertar o indivíduo de penúrias materiais, se consolidaram de maneira paradoxal na modernidade tardia, demonstrando que o funcionamento do capitalismo tem algo consigo de inerente que impossibilita a conclusão dos projetos previstos no início dessa trajetória da política, filosofia, ciência, economia, cultura e tecnologia ocidental. O ensaio tem o objetivo geral de articular a perspectiva das patologias do capitalismo, as cinco formas de alienação (de si e do outro, da natureza, do tempo, do espaço e das coisas) e as novas questões sociais que surgem a partir desse panorama.
Teoria Social no Antropoceno
Authors: Ferreira Herlaine
Published: May 2023

As mudanças climáticas estão cada vez mais evidentes através dos eventos extremos que colocam a humanidade a refletir sobre os impactos de sua ação na natureza ao longo do tempo. A modernidade buscou seu desenvolvimento sem considerar a esfera natural como componente de sua estrutura social, no entanto, o aquecimento global coloca em xeque não apenas a capacidade de ação da política holocênica, como toda a cultura que sustentou nossa sociedade até aqui. Neste cenário de mudanças climáticas, cabe à Teoria Social realizar um novo e eficaz diagnóstico de tempo capaz de auxiliar nossos atores a perceber os riscos atuais e as ferramentas necessárias para uma reflexividade da ação antrópica sobre o planeta. Neste artigo, nos propomos a entender a importância e as possibilidades de críticas da Teoria Social no contexto do Antropoceno.
Insurgência e re-existência: Formulações e reformulações da cultura caiçara frente avanço do turismo (Paraty-RJ)
Authors: Rodrigues Ana Cláudia
Published: May 2023

Este artigo tem como tema as características e os conflitos do embate da cultura tradicional caiçara (local) com acultura externa (global) à Paraty – Rio de Janeiro. O trabalho aponta os desafios enfrentados pelos moradoresnativos devido ao crescimento desenfreado do turismo, que vêm ao longo dos anos descaracterizando as regiõescosteiras e a cultura regional. Em suma, uma análise das formas de resistência da preservação da cultura caiçara,destacando manifestações dos moradores para tal feito, e exemplificando outros tipos de resistência, desejandoprocurar entender como os conhecimentos históricos por parte dos moradores dessas comunidades podem servircomo ponto de resistência e de resgate da cultural local, preservar esses modos de vida.
Reação anafilática e outras complicações após administração da ondansetrona: um relato de caso
Authors: De Almeida Laisy Amorim Farias , Lemos Renata Ferreira , Pontes Thiago Araujo , De Andrade Kelly Cristina Lira , Do Nascimento Graciliano Ramos Alencar
Published: May 2023

A ondansetrona é um fármaco antagonista do receptor 5-HT3 de serotonina precrito para o tratamento de náuseas e êmese. O medicamento apresenta como reações adversas comuns a cefaléia e constipação, como reações muito raras o broncoespasmo e a anafilaxia. A anafilaxia trata-se de uma reação que geralmente ocorre quando associada a drogas causadoras de bradicardia. É descrito o caso de um paciente, sexo feminino, 40 anos,  previamente hígida, a qual procurou o pronto atendimento com a queixa de tontura e mal estar, onde foi administrada a droga Cloridrato de Ondansetrona 8mg intravenosa e a paciente apresentou reação anafilática, convulsão e parada cardiorespiratória. A discussão deste trabalho, apesar de tratar de um evento adverso raro, é fundamental que seja considerada pela comunidade médica tendo em vista o amplo uso da droga e seus possíveis desfeichos graves no atendimento aos pacientes.
Relações entre contaminação de aquíferos subterrâneos no semiárido e disposição inadequada de resíduos sólidos
Authors: Alves João Batista , Dos Santos Mateus Macena
Published: May 2023

Os objetivos deste trabalho foram verificar quais as condições da qualidade das águas subterrâneas na região cristalina do semiárido brasileiro, se elas podem estar sendo contaminadas por agentes advindos da poluição, como o nitrato, e se são seguras para o consumo humano. O presente estudo é uma pesquisa de natureza exploratória qualitativa, baseada em fontes secundárias, como manuais, livros, papers em revistas científicas, teses etc. Como ferramenta de procura, utilizou-se o Google Scholar, Scopus, Web of Science, entre outras plataformas de busca. Pelo presente estudo, pode-se observar que o nitrato é uma substância de fácil mobilidade, através do processo de lixiviação, o qual é formado ao longo do processo de contaminação nos solos por diversas reações entre este, o líquido infiltrante, a água e microrganismos. O estudo leva a inferir que grande parte da região do semiárido brasileiro, onde predominam lixões e aterros controlados como destino final dos resíduos sólidos, encontrando-se sensivelmente vulneráveis à contaminação das águas subterrâneas, que naturalmente são armazenadas nos interstícios de fraturas e fissuras nas rochas. Sendo assim, essa região, uma área significativamente povoada, com escassez crônica de água, não pode prescindir dessa importante fonte de abastecimento. Isso leva a observar que tanto a população como os gestores públicos precisam levar a sério a questão da disposição final correta dos resíduos sólidos, pois são fontes inquestionáveis de poluição de aquíferos em médio e longo prazos, devido aos seus lixiviados. Pode-se, ainda, concluir que não é muito seguro o consumo dessas águas, sem um tratamento adequado.
Requirements and characteristics of materials for functional impressions in complete dentures: a literature review
Authors: Figueiredo Kaisa Lindomara dos Santos , Da Silva Júnior Jefferson Pires , Martins Jorge Henrique de Sousa , Cavalcante Bruna Mirely da Silva , Lima Daniel da Silva , Almeida Laíz Fernanda Tufi
Published: May 2023

Functional impression is one of the fundamental steps for the success of the rehabilitation treatment. Therefore, the objective of this work is, by means of a literature review, characterized as the main characteristics of the materials used in the functional impression in total prosthesis. The review was carried out through research in the database PubMed, Google Acadêmico, Lilacs and Scielo between the months of May to July 2020. Were used for the search of descriptors such as total prosthesis, materials for dental impression and dental materials. Secondary impression is divided into two stages: peripheral sealing and functional impression. The materials are classified as elastic and anelastic and must be used according to each clinical situation. To guarantee the quality of the functions, it is essential that all necessary steps are followed. In this context, being a functional molding conditioned according to the mucosa resilience, the present study was linked to describe the different materials, in order to ascertain their specificities according to the conditions of each individual. The professional must understand the characteristics of functional impression materials to develop better results in prosthetic rehabilitation, obeying the criteria obtained from the clinical examination of the patient, respecting the recommendations of each manufacturer of the material, and presenting the technique in which the dentist dominates and feel able to perform the procedure.
Síndrome de Burnout em docentes: fatores de risco e métodos para prevenção
Authors: Bergamini Raiane dos Santos , Amaral Pâmella Polastry Braga , Bergamini Robert dos Santos , Santos Caio Macueidi , Dos Reis Vanessa Oliveira , Marson Renan Fava , De Sousa Marlei Novaes , Antonucci Gabrielli , Alves Carolina de Oliveira , Da Costa Leonária Fernandes , Sampaio Neto Tarcilio José salles , Ronconi Nagila Mai , Da Silva Patrícia Batista , Feller Alexandre Andreatta
Published: May 2023

A Síndrome de Burnout tem se mostrado crescente, principalmente em profissionais da educação, onde diferentes causas têm sido remetidas ao surgimento da mesma, como carência de recursos, de suporte e pressões advindas da convivência interpessoal, gerando uma profissão de suma desenvoltura e estresse. O objetivo desse estudo é analisar através de uma revisão integrativa na literatura os principais fatores de riscos e estratégias para prevenção da SB em docentes. Trata-se de uma revisão integrativa da literatura proveniente da BVS com bases de dados da Scielo, LILACS e MEDLINE, através dos seguintes DeCS: Síndrome de Burnout”, “Docência” e “Fatores associados”, combinados entre si pelo operador booleano AND. Foram encontrados 128 estudos e selecionados 8 artigos para compor esta revisão. Os principais fatores associados a SB  descritas nos estudos foram as relações interpessoais, a falta de estrutura e ambiente adequados para o desenvolvimento do ensino, desinteresse por parte dos alunos, relação de desgaste com superiores e demais fatores como violência, assédio e questões relacionadas as necessidades humanas básicas, além de questões salariais, a desvalorização profissional e a alta jornada de trabalho. Os achados reforçam necessidade de aproximar políticas de saúde do trabalhador voltadas ao ambiente escolar/acadêmico, sobretudo na prevenção de causas de transtornos mentais relacionadas ao desenvolvimento da SB nesses profissionais.
Suplementação nutricional da coenzima q 10: dose terapeutica, custo e beneficio
Authors: De Moura Eduarda Kalyne Soares , Silva Emillayne Caroline Oliveira , Fidelix Marcia Samia Pinheiro
Published: May 2023

A coenzima Q10 é um composto encontrado em nosso corpo e tem atividade antioxidante, produz ATP, é lipossolúvel, de lenta absorção e circulação entero-hepática. Desde a sua descoberta, tem sido alvo de diversos estudos clínicos com o propósito de mostrar alterações nos seus níveis plasmáticos durante alterações fisiológicas ou patológicas e demonstrar os seus benefícios terapêuticos. O objetivo desta pesquisa foi fazer uma revisão bibliográfica de diversos artigos científicos publicados no Pubmed, Medline, BDENF e Sielo durante um período de 5 meses em inglês e português, descrevendo ensaios clínicos em que a coenzima Q10 é um possível elemento importante no tratamento de diferentes patologias. A coenzima Q10 tem sido amplamente estudada em certas patologias e tem demonstrado ter um papel terapêutico benéfico em inúmeros ensaios clínicos descritos. No entanto, é importante considerar a necessidade de estudos futuros para determinar com mais precisão e segurança os efeitos da coenzima Q10 na saúde.
Projeto terapêutico singular na assistência hospitalar: uma revisão integrativa da literatura
Authors: Gamarra Caren Renata , Macário Irma
Published: May 2023

O Projeto Terapêutico Singular consiste na elaboração de cuidados únicos e individuais a sujeitos que vivenciam alguma situação de adoecimento, sendo uma ferramenta importante para o sucesso do Sistema Único de Saúde brasileiro. Tal projeto é pensado para aplicar-se em todos os níveis de atenção à saúde, entretanto, sabe-se que a atenção hospitalar possui suas peculiaridades em  relação às demais. Dessa forma, objetivou-se realizar levantamento de pesquisas que abordassem a temática da utilização do Projeto Terapêutico Singular em unidade hospitalar. A pesquisa consiste numa Revisão Sistemática da Literatura com pesquisa as bases de dados Scielo, BVSaúde e PubMed de artigos na língua portuguesa e inglesa através do uso das palavras-chave e utilização de critérios de inclusão e exclusão. Observou-se a presença de poucos estudos, sendo estes com metodologias qualitativas. Ademais, tais pesquisas apresentaram resultados semelhantes como a presença de maior propensão à humanização, integralidade do cuidado, produção e manutenção e favorecimento da atuação interdisciplinar. Além disso encontrou-se desafios para a realização do projeto relacionados à obstáculos da rotina hospitalar, como recursos materiais e imateriais.
Índice de capacidade para o trabalho de enfermeiros atuantes em áreas críticas Covid-19: estudo transversal
Authors: Garcia Izabela Melo , Haddad Maria do Carmo Fernandez Lourenço , Malaquias Tatiana da Silva Melo , De Oliveira João Lucas Campos , Aroni Patricia
Published: May 2023

Objetivo: mensurar o índice de capacidade para o trabalho de enfermeiros nos diferentes turnos de um hospital universitário público com atendimento a pacientes com suspeita e confirmados com COVID-19. Método: estudo transversal realizado em hospital público de alta complexidade. A população do estudo foi constituída por enfermeiros atuantes no Pronto Socorro e Unidade de Terapia Intensiva Adulto e os resultados obtidos foram analisados por estatística descritiva. Resultados: dos profissionais entrevistados, 85,5%  eram mulheres; a idade média foi de 36,5 anos. Quanto a classificação de capacidade para o trabalho 7,3% foram classificados com ótima capacidade para o trabalho, 54,5% boa capacidade para o trabalho; 34,5% moderada capacidade para o trabalho; e 3,6% baixa capacidade. Conclusão: o Índice de Capacidade para o Trabalho dos colaboradores permite aos gestores a manutenção da boa capacidade para o trabalho, além de propor medidas de melhorias e promover um ambiente com condições de trabalho mais favoráveis.
Improvement of the female mouse computational model developed at CDTN
Authors: Rodrigues Joana D’Arc Souza , Mendes Bruno Melo , Leite Christiane Silva , Bispo Ana Carolina de Araujo , Ferreira Andrea Vidal , Silva Juliana Batista , Roivainen Anne , Jarmo Teuho
Published: May 2023

Small animals, such as mice, have been used in experiments involving ionizing radiation. New preclinical experimental methods often include extensive imaging (MicroCT and/or PET/SPECT) that can result in absorbed dose values considerably high. In addition, assays with theranosticsradiopharmaceuticals administered in small animals have been used to determine the main potential adverse effects and the therapeutic efficacy. For all these mentioned cases, the precise quantification of absorbed doses and the determination of energy deposition patterns are of fundamental importance to qualify or exclude potential radiobiological effects that may interfere with in vivo experiment results. Thus, the development and improvement of mouse phantoms is essential for good small animal dosimetry. In 2021, our group segmented and implemented a female C57BL mouse phantom, called FM_BRA, in the MCNP. The objective of this work was to review the segmentation of the FM_BRA computational model and to identify and segment new organs for an improved version of this phantom. Three different researchers segmented different organs of the model. The masses of the segmented organs were compared with those of the first version. Information on mass or volume of organs from different mouse strains, and more specifically from the C57BL strain, was also obtained from the literature for comparison and to aid in segmentation. The mice image representing a female mouse of the C57BL strain weighing 26 g were kindly provided by the Turku Center for Disease and were manually segmented. The software GIMP® 2.10 was used to select and segment each organ/tissue. The IMAIOS-VET Anatomy website was used as an anatomical basis for the identification of organs/tissues. The IMAGEJ® software was applied to assemble the segmented images into a 3D stack and to convert the segmented images into binary files. The volumes of the segmented organs were measured with a C++ in house program. Corresponding human tissue densities provided in ICRP 110 were used to calculate organ mass from the calculated volumes. Data were compared with literature reports. The number of segmented organs increased from 20 in the old model to 33 in the new models. The masses of the organs segmented in this work, by the different researchers, showed agreement in most cases. However, organs such as the small intestines, bones and trachea still deserve a new round of reviewing.
Henri Bergson: sobre a diferença entre a religião dinâmica e estática
Authors: Biasoli Severino Alexandre
Published: May 2023

O objetivo da presente pesquisa é examinar a temática da religião à luz da obra Duas Fontes da Moral e da Religião (1932) do filósofo francês Henri Bergson (1859-1941). Quais são as principais diferenças entre os conceitos ou definições sobre a definição de religião dinâmica e estática em Bergson? Para responder ao dilema filosófico, na primeira seção buscar-se-á definir o que é a religião estática (fechada), que busca manter o status quo individual e social. Posteriormente, conceituar o que é a religião dinâmica (aberta), que permite o encontro com o místico, a força da função fabuladora, o discurso do amor, a evolução individual e o homem respeitando-se a si ao mesmo tempo que pensa na humanidade em geral. O método de pesquisa será o hipotético-dedutivo, por meio de uma revisão bibliográfica de caráter exploratória e qualitativa. Conclui-se que a religião dinâmica é vinculada com uma experiência mística reservada a poucos indivíduos capazes de sentirem ou ouvirem o chamado divino. Esse sujeito místico com seu amor torna-se um exemplo na sociedade, que, por consequência, agrupa e passa a ser seguido, contudo este no fundo não tem pretensão de criar uma religião.
Enzyme Commission Number Prediction and Benchmarking with Hierarchical Dual-core Multitask Learning Framework
Authors: Shi Zhenkun , Deng Rui , Yuan Qianqian , Mao Zhitao , Wang Ruoyu , Li Haoran , Liao Xiaoping , Ma Hongwu
Published: May 2023

Enzyme commission (EC) numbers, which associate a protein sequence with the biochemical reactions it catalyzes, are essential for the accurate understanding of enzyme functions and cellular metabolism. Many ab initio computational approaches were proposed to predict EC numbers for given input protein sequences. However, the prediction performance (accuracy, recall, and precision), usability, and efficiency of existing methods decreased seriously when dealing with recently discovered proteins, thus still having much room to be improved. Here, we report HDMLF, a hierarchical dual-core multitask learning framework for accurately predicting EC numbers based on novel deep learning techniques. HDMLF is composed of an embedding core and a learning core; the embedding core adopts the latest protein language model for protein sequence embedding, and the learning core conducts the EC number prediction. Specifically, HDMLF is designed on the basis of a gated recurrent unit framework to perform EC number prediction in the multi-objective hierarchy, multitasking manner. Additionally, we introduced an attention layer to optimize the EC prediction and employed a greedy strategy to integrate and fine-tune the final model. Comparative analyses against 4 representative methods demonstrate that HDMLF stably delivers the highest performance, which improves accuracy and F1 score by 60% and 40% over the state of the art, respectively. An additional case study of tyrB predicted to compensate for the loss of aspartate aminotransferase aspC, as reported in a previous experimental study, shows that our model can also be used to uncover the enzyme promiscuity. Finally, we established a web platform, namely, ECRECer (
https://ecrecer.biodesign.ac.cn
), using an entirely could-based serverless architecture and provided an offline bundle to improve usability.
Etnografske svečane cipele - od restauracije do izrade kopije
Authors: Vladić Sara , Jemo Danijela , Serhatlić Sanja , Kodrič Kesovia Mateo Miguel
Published: May 2023

Etnografske svečane cipele opisane u ovom radu pripadaju bogatom fundusu narodnih nošnji Etnografskog muzeja, Dubrovački muzeji. Datirane su u kasno 19. st. i jedini su primjerak ovoga tipa cipela u zbirci. Kako bi se sačuvala materijalna forma i vrijednosti ovako jedinstvenog predmeta kulturne baštine ovoj se problematici pristupilo s dva aspekta. Prvo je proveden detaljan konzervatorsko-restauratorski zahvat nakon kojega je slijedila izrada njihove kopije, a sve prema odobrenju Konzervatorskog odjela Ministarstva kulture i medija RH. Konzerviranje i restauriranje višeslojnog, trodimenzionalnog predmeta izrađenog od tekstila i kože, poput etnografske obuće s područja Republike Hrvatske, izuzetno je zahtjevno, a osobito iz razloga što je to područje još uvijek nedovoljno istraženo.
Dizajn mini kolekcije obuće i modnih dodataka
Authors: Makšan Mia , Prahić Sanja , Kutnjak-Mravlinčić Suzana
Published: May 2023

U radu je sažeto prikazan proces dizajniranja, od ideje do realizacije, autorske mini kolekcije obuće i modnih dodataka inspiriranih umjetničkim pokretom suprematizam. U samom procesu dizajniranja posebna pozornost bila je upućena ka osmišljavanju idejnih rješenja iz više sastavnih dijelova s ciljem manjeg utroška materijala i mogućnosti primjene „upcycling“ metode, odnosno kreativne upotrebe proizvodnih ostataka kože u realizaciji modela. Eksperimentalni dio rada opisuje razvoj prototipa ženskih tenisica, gležnjača i ruksaka od idejnih rješenja, projektnih crteža, odabira materijala za izradu, do konstrukcije modela te izrade šablona. Primjenom digitalnih alata izrađeni su realistični prikazi budućih modela temeljem kojih su odabrani najatraktivniji i najprikladniji za izradu prototipa. U rezultatima rada prikazana je autorska mini kolekcija ženskih gležnjača, tenisica i ruksaka, s primarnim naglaskom na dizajn, funkcionalnost i kvalitetu te mogućnost dužeg vijeka trajanja i primjene u skladu sa smjernicama održive mode.
Criminalisation of Specific Forms of Online Communication: a South African Legal Perspective
Authors: Watney Murdoch
Published: May 2023

One of the key findings of the South African Social Media Landscape 2022 study is that the growth in Internet access has, in turn, spurred the use of social media, leading to an estimated 48.8% (28 million) of South Africans being active on social media platforms, such as Facebook, Twitter, Instagram, YouTube, LinkedIn and TikTok. The down side is that online communication may not only become “viral” but it may also be harmful.

 

Initially Internet regulation focussed primarily on the criminalisation of unlawful online conduct, referred to as a cybercrime, which includes hacking, DDoS attacks, but now the focus has been extended to the criminalisation of specific forms of online communication, referred to as communication offences, which include postings on Facebook or WhatsApp.

 

The discussion deals with the criminalisation of specific forms of online communication in South Africa, the enforcement of communication offences with reference to the investigative powers of the police, with assistance from service providers, and the manner in which a balance between free speech and security is ensured. It does not deal specifically with the protection of users against harmful content, although a possible consequence of the criminalisation of communication is protection against these forms of communication.
Factors Influencing Information Adoption From Social Media About COVID-19 by Saudi Citizens.
Authors: ALMALKI SUAAD , Uren Victoria , Hall Matthew
Published: May 2023

Social networking sites comprise an open world where anyone can share different types of information. During the Covid-19 pandemic, people's social isolation made social media particularly important, and it has emerged as an important platform for sharing health information. The credibility of the information, however, is questionable. Therefore, this study aims to understand attitudes towards using social media as an information source among social media users in Saudi Arabia. Specifically, it seeks to examine the propensity of individuals towards using health information from social media platforms and whether individuals demographic factors (such as gender) impact information adoption. Based on using an online questionnaire incorporating a novel vignette design to measure participants’ perceptions of information sources on social media platforms. The findings revealed that there is a high use of social media platforms among the Saudi population and that verified accounts on social media platforms, same gender and nationality positively affect the propensity towards adopting information.
Social Media Use and its impact on Egyptian MSMEs’ Growth
Authors: FAKHRELDIN HADIA , Miniesy Rania
Published: May 2023

Micro, small and medium enterprises (MSMEs) have benefited significantly from the use of social media (SM) in reaching customers and growing sales in a most efficient way. This study compares Facebook and Instagram as two separate social media platforms and examines to what extent the use of each of these SM platforms affects the growth of MSMEs. It distinguishes financial growth and non-financial growth and uses two theories to conceptualize the relations within the context of social media usage: the Social Exchange Theory (SET) and the Task Technology Fit (TTF) Theory. Results of the quantitative and qualitative analysis based on data of 383 MSMEs show that using social media (SM) has helped MSMEs achieve both financial and non-financial growth. Facebook, more specifically, leads to financial growth (higher sales volume in the short-term), while Instagram leads to more customer engagement and higher brand performance, with the positive and significant moderating effect of the length of social media use.