bluuebunny/crossref_metadata_2025 huggingface dataset:
A Concise Review on Synthesis, Anti-inflammatory and Antioxidant Activities of Chalcone
Authors: Singh Dheeraj , Kaundal Vishal , Aggarwal Neha , Jindal Shammy , Ankalgi Amar Deep , Goyal Kamya
Published: March 2022

Chalcones and their derivatives have been an area of great interest in recent years. Numbers of research publications have been published and chalcones continue to show promising effect for new drug investigations. Chalcone is an advantageous species with medicinal importance as it is consisting of highly reactive ketoethylenic system –CO–CH=CH– which belongs to flavonoids. Chalcones (1, 3-Diphenyl-2-propen-1-one) consists of a three carbon α, β-unsaturated carbonyl system and two or more aromatic rings and acts as precursors for the biosynthesis of flavonoids in plants. However, synthesis in laboratory of broad range of chalcones has also been reported. In chalcone and its derivatives, a highly reactive α, β-unsaturated carbonyl system is the major reason for their pharmacological potencies. Chalcones and their derivatives are known to show a wide range of pharmacological potencies such as anti-inflammatory, antioxidant, antileishmanial, antifungal, anticancer, antibacterial, antiulcer, antiprotozoal, antitumor, antimalarial, antidiabetic, anthelmintic, insecticidal, antigout, antihistaminic, antiviral, antimycobacterial etc. Chalcones can be prepared by Claisen–Schmidt’s condensation, Aldol condensation, Heck’s reaction, Suzuki’s reaction, Ultrasound method of synthesis, Solvent free synthesis of chalcones, One pot synthesis, Sonogashira Isomerization coupling reaction etc. The purpose of the present review is to focus on the various methods of preparation of chalcones and derivatives and their anti-inflammatory and antioxidant potencies.
Corona Virus Disease (COVID-19): A past and Present Prospective
Authors: Talele Swati G. , Ahire Eknath D. , Surana Khemchand R. , Sonawane Vijayraj N. , Talele Gokul S.
Published: March 2022

Background: Corona virusis identified since 2002 and from seven strain severe acute respiratory syndrome corona virus and middle east respiratory syndrome corona virus causes severity in patients and then in December 2019, an outbreak of severe acute respiratory syndrome Corona virus 2 infection ensued in Wuhan, China and spread crosswise China and beyond. On February 12, 2020, WHO officially named the disease caused by the novel Corona virusas Corona virus Disease 2019 (COVID-19). Main Text: This form of virus comes up its growth when expose to any of the naturally expose material and the precaution for this is only single oriented, that is keeping yourself hygienic by washing your hands by utilizing high grade sanitizer. The literature survey revealed that Corona virus strain mainly severe acute respiratory syndrome corona virus and middle east respiratory syndrome Corona virus and human corona virus preserve on various surfaces like metal, glass or plastic for about 9 days but inactivation of virus by utilizing various virucide. On infection, the virus has a surge of proinflammatory cytokines and chemokines, which do damage to lung tissue, deterioration of lung function, and then eventually go to lung failure. Drug discovery against the virus is a challenging line of work owing to frequent recombination events. The evolution of a vaccine is another significant facet. Research is in ongoing stage to develop vaccine and medicines for COVID 19. In such circumstances, other system of medicineis widely used, like Allopathy, Ayurveda and Unani. Unani system of medicine utilized some measures for health protection during epidemics. In Unani medicine, during an epidemic, apart from isolation and quarantine, three measures are of utmost importance, impurification of surroundings using certain herbal drugs as fumigants or sprays, health promotion and immune-modulation, and use of health-protecting drugs and symptom-specific drugs. Conclusion: We require more structural biological details which put up rush up the drug or vaccine development process against corona virus. Thus, objective of this follow-up article is to focus on past to present perspective on corona virus pandemic.
Herbal Drugs used in the Management of Diabetic Nephropathy
Authors: Savant Priti B. , Kareppa Manjusha S. , Karwa Pawan N. , Birajdar Nikita , Jangid Monika S.
Published: March 2022

Diabetic nephropathy (DN) or diabetic kidney disease refers to the deterioration of kidney function seen in chronic type 1 and type 2 diabetes mellitus patients. The progression of the disease is known to occur in a series of stages and is linked to glycemic and blood pressure control. Diabetis nephropathy is a kidney disease. In normal conditions the function of kidney help to regulate fluids and salts balance in the body, which is vital for control blood pressure (BP) and protect cardiovascular condition. In Diabetic condition increases blood sugar levels in high, this sugar level increase long time of the period then these high glucose levels can damage various regions of the body including the cardiac system and kidney. Damaging of kidney that results or this condition is termed as diabetes nephropathy. The average incidence of diabetic nephropathy is high (3% per year) during the first 10 to 20 years after diabetes onset. Typically, it takes 15 years for small blood vessels in organs like kidney, eyes and nerves to get affected. It is estimated that more than 20 and up to 40% of diabetic patients will develop chronic kidney disease (CKD).
A Systemetic and Scientific Review on the Acmella oleracea and its Traditional Medical and Pharmacological uses
Authors: Savant Priti B. , Kareppa Manjusha S.
Published: March 2022

Acmella oleracea L. R.K. Jansen belongs to the family Asteraceae is generally termed “toothache plant”. Though complex pattern has present or shows in the Acmella genus, the cylindrical discoid capitula which has a golden yellow in color with red tip make it unique. It is an annual herb, occurring around the world and, It is cultivated for horticultural and pharmacological purpose it is used in the treatment or prevention of various diseases or disorders in the human being or animal rheumatism, stuttering, paralysis of the tongue, antipyretic i.e. reduce body temperature, sore throat and gum infections. There are also others reports of the use of Spilanthes acmella, such as spices such as antiseptic i.e. these are the agents which are used to kill the growth of the microorganism on living tissue, antibacterial i.e. kill or inhibit the growth of bactria, antifungal, antimalarial i.e. these are the drug or agent which are used to inhibit or kill the parasite responsible for cause of malarial infection, remedy for toothache, influenza, cough i.e. Expel the mucos sectretions from the respiratory tract and tuberculosis i.e. These are drug or agent which are used to inhibit causative microorganism of tuberculosis mycobacterium tuberculosis etc.
COVID-19 Vaccines: Bioethical Consideration
Authors: Andrade Sérgio Araújo , Andrade Patrícia Alves da Costa , Andrade Daniel Vaz , Santos Regina Consolação dos , Varotti Fernando de Pilla , Lwaleed Bashir Abdulgader
Published: March 2022

The COVID-19 pandemic produced immeasurable impacts on the economy, education, and socialization, besides the loss of millions of lives. Thus, there has been an accelerated development of an unprecedented number of COVID-19 vaccine candidates to control the pandemic. The World Health Organization’s emergency use authorization of COVID-19 vaccines still in clinical trial allowed immunizing the population. This paper presents a perspective of the bioethical precepts of autonomy, non-maleficence, beneficence, and justice in the emergency use of COVID-19 vaccines. Furthermore, it emphasizes the importance of surveillance at all stages of vaccine development to detect adverse effects and ensure compliance with bioethical precepts.
Solution of Non-linear Fractional Burger's Type Equations Using The Laplace Transform Decomposition Method
Authors: ILHEM Kadri , AL HORANİ Mohammed , KHALİL Roshdi R
Published: March 2022

Our goal in this paper is to use combined Laplace transform (CLT) and Adomian decomposition method(ADM) (that will be explained in section 3), to study approximate solutions for non-linear time-fractionalBurger's equation, fractional Burger's Kdv equation and the fractional modi?ed Burger's equation for theCaputo and Conformable derivatives. Comparison between the two solutions and the exact solution is made.Here we report that the Laplace transform decomposition method (LTDM) proved to be e?cient and beused to obtain new analytical solutions of nonlinear fractional di?erential equations (FDEs).
Sustainable Pricing-Production-Workforce-Routing Problem for Perishable Products by Considering Demand Uncertainty; A Case Study from the Dairy Industry
Authors: Majidi Ali , Farghadani-Chaharsooghi Pedram , Mirzapour Al-e-Hashem S. Mohammad J.
Published: March 2022

The production routing problem seeks to simultaneously optimize production, routing, and inventory decisions for the plant and the suppliers. In this article an integrated multi-objective sustainable pricing-production-workforce-routing problem is presented for perishable products. Total profit, workforce planning, and vehicle fuel consumption are considered as objective functions due to the importance of operational performance, social, and environmental concerns. The application of the proposed approach is investigated using real case data from a dairy product supply chain. Furthermore, a new solution approach, called Fuzzy Domination Self-Learning Non-Dominated Sorting Algorithm (FDSL-NSGA-II), is developed to solve the problem. The results show that the Pareto solutions of FDSL-NSGA-II outperform those of the classic NSGA-II. Moreover, the findings show that the proposed model can create a surpassing tradeoff between the various aspects of a supply chain, including production, distribution, and workforce planning. In addition, it concurrently optimizes the selling price and protects the environment from the negative impacts of greenhouse gas emissions (GHGs). A comprehensive analysis of the results reveals several managerial insights for decision makers in the logistics industry.
An Analysis of Amazon Air's Network in the United States
Authors: Bowen John T.
Published: March 2022

Using data on 12 months of operations, Amazon Air's network is contrasted to the domestic networks of FedEx Express and UPS Airlines. Amazon Air has a lower network density than the other two airlines, and its geography is more strongly related to Amazon's distribution centers. Like UPS and FedEx, Amazon has placed its main hub at a location in the central United States: first Wilmington, Ohio and more recently Cincinnati. The acceleration of online retail trade since the onset of the COVID-19 pandemic may encourage other digitally native or incumbent retail firms to develop their own air distribution networks. The criteria that distinguish Amazon Air's gateway airports are identified and then those criteria are applied to all public US airports to detect others that might be suitable for incorporation into a retail distribution air network.
Potential use of Janus structures in food applications
Authors: Subasi Busra Gultekin , Xiao Jianbo , Capanogluo Esra
Published: March 2022

Janus surfaces present technological opportunities both for research and industry in which different chemical, physical and/or structural components need to coexist for a single purpose such as chemistry, textile and material science. Varying inorganic and organic (polymer‐based) materials are conventionally used however, utilizing nature‐derived polymers to fabricate Janus structures is a recent and attractive trend which makes them more applicable for bio‐based treatments with environmental concerns. Particularly, promising applications of Janus structures as being surfactants, drug delivery and micro/nano encapsulation vehicles for biomedical purposes successfully forward the interest on Janus concept to the food related practices. Producing Janus structures from nature‐derived and food grade polymers such as alginate, cellulose, chitosan, lipid nanocrystals, zein and some plant‐proteins and their usage stronger emulsions with higher stabilities, biosensing or antimicrobial practices as well as bioactive delivery and release control might be considered as a new era for food processing industry.
Xanthine oxidase targeted model setup and its application for antihyperuricemic compounds prediction by in silico methods
Authors: Hou Chuanli , Shi Chuanchao , Ren Jiaoyan
Published: March 2022

To achieve potential alternatives for hyperuricemia therapeutics, a novel structure‐docking energy relationship model was established for high‐throughput screening inhibitors of xanthine oxidase (XO). Molecular docking was performed between XO and 311 natural compounds from 6 traditional Chinese herbs. Then, structure‐docking energy relationship model was simulated between molecular docking energy and 63 molecular descriptors by multiple linear regressions (MLR), principal component regression (PCR), and artificial neural network (ANN), respectively. The results showed that the ANN model was the best model to predict the docking energy of XO with the coefficient of determination (R2) and mean squared error (MSE) at 0.8746 and 0.9414, respectively. The data of XO inhibitory activity were consistent with the prediction in vitro, which was also further confirmed by hyperuricemia cell model. The results suggested that the structure‐docking energy relationship model provides a paradigm framework for the screening of XO inhibitors.
Primarias en América Latina: hacia una tipología tridimensional
Authors: Carranza Pinedo Narda , Chuquillanqui Gonzales Manuel
Published: March 2022

Existe un reconocimiento de que las primarias son mecanismos de selección de candidatos con variaciones nacionales relevantes en Latinoamérica; sin embargo, los enfoques convencionales aún no incorporan este hecho. Por este motivo, ofrecemos una tipología descriptiva de primarias, enfatizando tres dimensiones: el grado de su obligatoriedad (alta o baja), el grado de control estatal (por ejemplo, participación estatal en el proceso) y el tipo de inclusividad del selectorado (primarias abiertas y/o cerradas). Este marco permitiría a los/as académicos/as desarrollar explicaciones más exactas y precisas acerca del diseño, la implementación y evaluación del instrumento, mejorando la selección de casos dentro de los estudios comparados al respecto. Ilustramos la utilidad de este marco analizando el caso peruano.
Digital relief model based calculation of basic geomorphological parameters of elementary relief surfaces in digital platform of Adyghea precision agriculture
Authors: Плисенко Ольга Анатольевна , Варшанина Татьяна Павловна
Published: March 2022

Рассмотрены вопросы разработки алгоритмического обеспечения цифровой поддержки экологически сбалансированного точного земледелия в Республике Адыгея. Представлено описание основных техник расчета геоморфологических параметров и инсоляции виртуальной модели поля. Разработаны алгоритмы расчета уклона, экспозиции и инсоляции для элементарных поверхностей - структурных элементов модели.

The paper deals with the development of algorithmic provision of digital support of ecologically balanced precision agriculture in the Republic of Adyghea. The publication describes basic techniques for calculating geomorphological parameters and insolation of a virtual field model. The authors develop the algorithms for calculating slope, exposure and insolation for elementary surfaces - structural elements of the model.
Some questions of studying electrical characteristics of thermoelectric elements using Arduino hardware and software platform
Authors: Меретуков Шумаф Туркубиевич , Полякова Светлана Владимировна , Меретукова Сусана Касеевна
Published: March 2022

Рассмотрены вопросы автоматизации процесса измерения электрических характеристик термоэлектрического преобразователя,элемента Пельтье, на основе аппаратно-программной платформы Arduino. Описаны возникающие трудности, связанные с физическими особенностями элемента Пельтье и возможностями Arduino.

The paper discusses the automation of measuring the electrical characteristics of a thermoelectric converter, Peltier element, based on the Arduino hardware and software platform. The authors describe the emerging difficulties associated with the physical features of the Peltier element and the Arduino potentialities.
Improving Iris Dataset Classification Prediction Achievement By Using Optimum k Value of kNN Algorithm
Authors: ÇELİK Ahmet
Published: March 2022

Machine learning methods are widely used in automated technologies. Classification prediction is a machine learning based on data mining. Today, many technological devices can make new predictions by gaining experience from past data with machine learning methods. Machine learning is widely studied in two types, supervised and unsupervised. The limits of the objectives in supervised learning are predetermined. In unsupervised learning, there are no predetermined targets. In this learning, the machines are required to determine the targets automatically. Prediction process is one of the basic components of machine learning. Machines need to use some algorithms in order to perform the prediction process on the basis of data mining. k nearest neighbor (kNN), Naive Bayes (NB), Decision Tree (DT) and Support Vector Machine (SVM) algorithms are used mostly. k nearest neighbor (kNN), Naive Bayes (NB), Decision Tree (DT) and Support Vector Machine (SVM) algorithms are used mostly. These algorithms can be applied with the help of some tools on data sets. In this study, kNN algorithm was used to estimate Iris data set classification using Orange tool. The success of the KNN algorithm depends on using the correct attribute and changing the optimum k value. As a result of the tests, it was determined that when the k neighbor value was selected as 15, it was the most suitable k neighbor value, providing 98.67% classification prediction success in the Iris dataset.
Pelatihan Penggunaan Mendeley sebagai Alat Sinkronisasi Metadata Artikel Ilmiah
Authors: Sucipto Sucipto
Published: March 2022

Mendeley merupakan salah satu alat yang familiar di kalangan penulis sebagai alat bantu pengutipan referensi naskah ilmiah. Penggunaan mendelay masih dianggap sebagai alat yang serba otomatis, sehingga masih banyak pengguna kurang teliti mengenai metadata artikel yang masuk pada kutipan maupun daftar referensi. Maka dari itu, kegiatan pengabdian ini bertujuan untuk memberikan pelatihan mengenai penggunaan Mendeley sebagai penunjang penulisan naskah ilmiah dengan memperhatikan faktor kelengkapan metadata sehingga setiap metadata dapat sinkron dengan naskah ilmiah yang dikutip. Pelatihan ini dilakukan secara offline sesuai dengan aturan protokol Covid-19. Hasil pelatihan ini menunjukkan bahwa peserta mendapatkan pemahaman mengenai metadata naskah ilmiah dengan bantuan perangkat lunak Mendeley.
Penerapan Video Edukasi untuk Meningkatkan Pemahaman Penggunaan Ramuan Herbal Selama Pandemi Covid-19 bagi Kelompok Remaja Kecamatan Loceret Kabupaten Nganjuk
Authors: Santoso Agus Muji , Hanggara Guruh Sukma , Afandi Zainal , Mujiwati Endang Sri , Budiono Heru , Primandiri Poppy Rahmatika , Setyowidodo Irwan , Nurfahrudianto Aan , Irmayanti Elis , Aizah Siti , Darmawan Ericka , Ristanto Rizhal Hendi , Siswati Bea Hana , Amin Mohamad , Puspitasari Yulianna , Julianto Tri
Published: March 2022

Ramuan herbal dapat berpotensi besar untuk meningkatkan ketahanan tubuh dalam masa pandemi jika digunaan secara tepat. Rendahnya pengetahuan tentang takaran, teknik pengolahan, pola konsumsi ramuan herbal, dan efek sampingnya menjadikan fokus untuk program pengabdian masyarakat dengan memberikan informasi yang komprehensif tentang penggunaan ramuan herbal yang dapat meningkatkan daya tahan tubuh secara baik dan benar. Program pemberdayaan masyarakat dilaksanakan dalam moda daring melalui media jejaring sosial secara asinkronus sesuai tahap ODSIMED (observasi, pengembangan, sosialisasi, implementasi, monitoring, evaluasi, diseminasi) Program ini mampu meningkatkan  pengetahuan masyarakat sasaran tentang penggunaan ramuan herbal yang tepat. Khususnya tentang teknik pengolahan ramuan herbal (skor N-Gain 0,77).
Upaya Pencegahan Penularan Covid-19 pada Masyarakat Kab. Kediri
Authors: Mudzakkir Muhammad , Risnasari Norma , Nugraha Muhammad Frinata Erian , Mawadha Sarah Azmillaely
Published: March 2022

Coronavirus Disease 2019 (Covid-19) adalah suatu penyakit menular yang disebabkan oleh Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Cov-2) yang jumlah kasusnya masih terus meningkat. Berbagai upaya telah dilakukan untuk menurunkan penyebaran covid-19 agar kasusnya tidak semakin meluas. Masyarakat mempunyai peran yang penting melalui tindakan pencegahan dan pengendalian untuk memutus mata rantai penularan agar tidak terjadi sumber penularan baru. Metode yang digunakan dalam kegiatan pengabdian ini dengan melakukan penyuluhan kesehatan dengan pendekatan partisipatif, yang bertujuan meningkatkan pengetahuan masyarakat terhadap covid-19. Kegiatan dilaksanakan di Desa Ngadi, Kecamatan Mojo, Kabupaten Kediri tanggal 2 Maret 2021. Berdasarkan analisis diskriptif dari pertanyaan berupa kuesioner yang diberikan kepada peserta didapatkan hasil pre-test penyuluhan hanya 8% menyatakan tahu tentang pengertian covid-19, 24% mengetahui jenis coronavirus penyebab covid-19, 48% mengetahui tanda dan gejala covid-19 dan 52% menyatakan belum paham tentang pencegahan penularan covid-19. Hasil post-test dengan pertanyaan yang sama didapatkan seluruh peserta menyatakan paham tentang pengertian dan pencegahan covid-19 serta hampir seluruhnya memahami jenis virus penyebab covid-19 (92%) dan memahami tanda dan gejala (96%). Hasil tersebut menunjukkan terjadi peningkatan pengetahuan peserta penyuluhan kesehatan tentang upaya pencegahan penularan covid-19.
Some characteristics about the process of Nguyen empiers established Vietnam Southwestern Sea and Islands Area's Sovereignty in the 18th Century
Authors: Tuan Hoang Van
Published: March 2022

In the process of expanding his territory to the South, Lord Nguyen appreciated the importance of the Southwestern sea and islands for the cause of establishing a "kingdom" of his own. The process of establishing sovereignty over the Southwestern seas and islands was carried out from 1708 to 1757 and was completed. The article focuses on clarifying the main features of the process of establishing sovereignty over the Southwestern seas and islands to fully realize: (i) the difficulties and challenges faced by Lord Nguyen and the Mac family, (ii) the strategic vision of Lord Nguyen's strategy for domestic and foreign activities, (iii) the contributions of the Mac family in the process of establishing sovereignty over the Southwestern sea and islands.
Farmer empowerment in agriculture and its association with smallholder farm incomes in Kenya
Authors:   Department of Agricultural Economics, University of Nairobi, Nairobi, Kenya, Mwololo Henry , Nzuma Jonathan ,   Department of Agricultural Economics, University of Nairobi, Nairobi, Kenya, Ritho Cecilia ,   Department of Agricultural Economics, University of Nairobi, Nairobi, Kenya
Published: March 2022

Poverty in its various forms is widespread among smallholder farmers, including income poverty, rendering interventions that improve household income relevant. We employ a linear model on crosssectional data collected from October to December 2015, with the preceding 12 months as the reference period. The data was from 835 smallholder farmers in Kenya to assess the effect of farmer empowerment in agriculture on farm income. This is a departure from numerous previous studies, which considered the intra-household empowerment of women relative to men on the assumption that men are empowered, which may not always be the case – as we show in this study. The results show that farmer empowerment in agriculture increases per capita farm incomes. Unlike male farmers, who benefit from the overall empowerment in agriculture, female farmers do not, possibly due to constraints in complementary drivers of farm income such as access to productive resources. Interestingly, improving the income domain for female farmers increases their farm incomes more than for their male counterparts. We conclude that farmer empowerment in agriculture is a necessary driver of farm incomes, with the production, leadership and income domains being the viable impact pathways. Thus, development interventions should target specific empowerment domains while controlling for sex differences among the target farmers.
Licensing Online Content to Ensure Patron Privacy: An Informal Survey of Oregon Librarians
Authors: Emery Jill
Published: March 2022

Librarians throughout Oregon are committed to securing the rights for patrons utilizing resources within their libraries with the greatest level of protection regarding their online identities as possible. At the same time, Oregon librarians are committed to providing their patrons with the online resources they want to access whether it is a public library, an academic library, a community college library, or a health services library. Finding the balance between providing the desired online content with the safeguards that protect their patrons can be difficult. Oregon librarians recognize the need to secure patrons' online privacy but also want to meet patron demands for resources. Patrons tend to prioritize their quest for content over their personal privacy concerns. By contrast, librarians evaluate the privacy needs of their community as a whole as opposed to on an individual level. They are committed to the third principle of the American Library Association's Code of Ethics: "We protect each library user's right to privacy and confidentiality with respect to information sought or received and resources consulted, borrowed, acquired or transmitted" (ALA, 2021).
As with many issues in the 21st century, a tension exists between the individual's wants and the best practices for community well-being. To better understand this inherent conflict between access and security, I asked several Oregon librarians to answer a series of questions about their electronic resource licensing practices. This article outlines the current practices these colleagues employ to reconcile this tension between patron demand and patron safety and to identify ways for improving the situation regarding online resource usage.
Antidepressant safe use, deprescription and switching guideline
Authors:   Servicio de Asesoría e Información del Medicamento. Servicio Navarro de Salud - Osasunbidea, Goñi Oihane
Published: March 2022

INTRODUCTION Antidepressant use has increased over the past few years. Given the lack of evidence concerning differences in efficacy between the various antidepressants, it is important to understand the safety profile to ensure the safe use thereof. Antidepressant treatment typically lasts for too long, partly due to the absence of specific deprescription guidelines. An understanding of the best methods for switching between antidepressants, and the most suitable methods for deprescribing, may help to optimise the pharmacotherapy of depression. OBJECTIVES To establish suitable guidelines for the prescribing, switching, use and deprescribing of antidepressants. METHODS A search was carried out for clinical practice guidelines, systematic reviews and bulletins to compile the evidence available regarding the correct use and deprescribing of antidepressants. The prescription database of the Servicio Navarro de Salud-Osasunbidea (SNS-O) [Navarre Health Service] was used to obtain data regarding antidepressant use in Navarre. CONCLUSIONS When planning the treatment of depression it is necessary to consider, initially, whether the prescription of an antidepressant drug is actually indicated in that specific situation. Secondly, it is crucial to think about the characteristics and comorbidities of the patient when selecting the most appropriate drug. In this regard, before adding a new drug, pharmacotherapy must be optimised by increasing the dose, waiting for the appropriate amount of time and considering switching to another antidepressant. Finally, treatment must be reassessed periodically considering that such treatments are not for life and withdrawal of the drug gradually and with the patient’s consent should be evaluated to increase the likelihood of a successful withdrawal
Kajian Pelayanan Pelaksanaan On The Job Trainining (OJT) Taruna di Politeknik Penerbangan Indonesia Curug Tangerang
Authors: Sugih Arti Endang , Wagini Dini
Published: March 2022

This study discusses the implementation services of OJT cadets at PPI Curug. The research method used is descriptive analysis, namely analyzing the problem of lecturers' anxiety about the implementation of OJT cadets and the data collection methods are interviews, literature study and questionnaires by distributing question sheets to OJT Instructors at 24 airports as OJT locations in Perum LPPNPI. Furthermore, the data is measured according to the Slovin formula with an error rate of 5%. This study aims to determine the conditions of service for the implementation of OJT for cadets at PPI and to find out the obstacles that occur in it and to find alternative solutions. The results obtained from the research that the OJT implementation service did not match expectations. From the various obstacles, suggestions for improvement are proposed.
Analisis Rancangan Workshop Sheet Metal Untuk Meningkatkan Keselamatan Dan Efisiensi Kerja di PT. Merpati Maintenance Facility Surabaya
Authors: Wicaksono Reno Widyo , Mursyidin  , Kurniawan Iwan Engkus
Published: March 2022

Penelitian ini bertujuan untuk melengkapi dokumen safety management system dan mengubah tata letak workshop sheet metal PT. Merpati Maintenance Facility Surabaya. Adanya penurunan tingkat keselamatan dan efisiensi yang didapati penulis berdasarkan hasil dari observasi lapangan. Berdasarkan kondisi yang ada maka penulis akan mengolah data dengan menggunakan pendeketan desktiptif kualitatif dan kuantitatif atau HIRAM (Hazard Identification, Risk Assesment and Mitigation) serta gap analisis untuk mengalisis dan mengolah data yang ada menggunakan metode HIRAM yang kemudian ditindak lanjuti dengan pembuatan tata letak yang baru. Kesimpulan pada penelitian ini yaitu mendapati risiko bahaya yang memiliki nilai tinggi sehingga harus dilakukan pengendalian untuk menurunkan risiko dari bahaya menjadi tingkat resiko yang dapat diterima dan pembuatan tata letak baru dari workshop sheet metal. Saran dari hasil penulisan ini yaitu agar PT. Merpati Maintenance Facility melaksanakan tindakan mitigasi hasil dari penilitan ini dan melakukan perubahan tata letak minimum sebagaimana yang dirancang oleh penulis.
Radar study of the cyclonic storm of 21 September 1962 in the Bay of Bengal
Authors: BHATTACHARJEE P. , DE A. C.
Published: March 2022

Radar observations of the cyclonic storm of2lSeptember .1962, taken at Dum Dum Airport Calcutta with the help of a 3-cm Japanese (Type NMD-451A) radar have been reported in this communication. Movement of the storm and associated observed echoes in the form of spirals or bands have been shown. Characteristics of the storm and distribution of rainfall have also been described.
Radar-climatology of Delhi and neighbourhood : Convective cells of the hot weather season
Authors: KULSHRESTHA S. M. , JAIN P. S.
Published: March 2022

The paper presents a radar--climatological analysis of the cell-census for Delhi and neighbourhood based on the New Delhi radar data for the hot weather seasons of 1958, 1959 and 1960. The object is to investigate the various characteristics of the echo cells, The study covers cell-diameters, cell-spacings, their distributions, variations with the progress of the season, their inter-relationships,  height-diameter relationships, etc.
An explanation of anomalous radar propagation following thunderstorm activity
Authors: RAGHAVAN S.
Published: March 2022

Several cases of anomalous propagation of a 3.cm radar beam observed at Madras in the rear of thunderstorms, cannot be satisfactorily explained by the process suggested by previous workers on this subject, The anomalous echoes appear to be from ground targets, obtained after partial reflection of the radar beam at a thin boundary layer between the downdraught air of the thunderstorm and the environmental air, "Sufficient refractive Index change, required to produce the reflection can occur only in cases when the down draught air is more moist than the environment, and this agrees with the observations, The mechanism suggested does not depend on the presence of rainfall at the ground.
A simple device for the calibration of the Optical Wedge of the Dobson's Ozone Spectrophotometer
Authors: SINHA S. S. , SANYAL S. K.
Published: March 2022

The calibration of the optical wedge of the Dobson's Ozone Spectrophotometer is being done by the two well known methods, viz., (1) from sunlight with the help of perforated gauze and (2). by rhodiumised plate and standard lamp, the transmission coefficients of perforated gauze and rhodiumised plate being known.

 

In this paper the result of the calibration of the optical wedge of the Dobson's Spectrophotometer by means of a circular diaphragm cutting the light intensity from a standard lamp to a known percentage has been explained.
Musculoskeletal Metastasis From Soft-tissue Sarcomas: A Review of the Literature
Authors: Pretell-Mazzini Juan , Seldon Crystal S. , D'Amato Gina , Subhawong Ty K.
Published: March 2022

Soft-tissue sarcomas are a rare and extremely heterogeneous group of cancers, representing <1% of all human malignancies. The lungs are the most common site of distant metastasis, followed by the bone, lymph nodes, liver, brain, and subcutaneous tissue. Clinical experience suggests that skeletal metastasis is part of the natural history affecting the prognosis and quality of life in these patients. Approximately 2.2% of patients have skeletal metastasis at diagnosis. However, up to 10% will develop skeletal metastasis after a mean interval of 21.3 months. Although systemic therapy with conventional chemotherapy remains the primary treatment modality for those with metastatic sarcoma, increased survival has been achieved in selected patients who receive multimodality therapy, including surgery, for their metastatic disease. The 5-year overall survival of patients with isolated bone metastases was 41.2% (26.9% to 54.9%), which decreased to 32.9% (21.2% to 45.1%) in the setting of combined bone and lung metastases. Moreover, the resection of the primary soft-tissue sarcoma is a predictor of survival, resulting in a 58% decrease in mortality after surgery (hazard ratio, 0.42, P = 0.013). Understanding the effect of these metastases on patient survival may influence imaging, surveillance, and treatment decisions.
LEGAL CERTAINTY FOR HEALTH FACILITIES IN PROVIDING REFERRAL LETTER ON PATIENT REQUESTS IN THE JKN ERA (JURIDICAL REVIEW OF THE SJSN LAW AND BPJS HEALTH LAW)
Authors: Satria Beni
Published: March 2022

The main problem in this research is a policy problem, namely the problem of legal policy in regulating the rules of legal certainty for health facilities. Therefore the approach to this problem is a policy-oriented approach. However, considering that the main target of this research is legislative policy in formulating legal certainty for health facilities in carrying out their duties and functions, the approach is mainly taken with a juridical-normative approach. This research was conducted at the Blangkejeren Public Health Center, Lhoksukon City, Central Aceh, with literature studies at the Panca Budi University Library and internet searches. The data sources of a research are primary data and secondary data. Because this research is a normative legal research, the sources studied are secondary data sources. Legal certainty of payment for health services has provided legal certainty to Health Service Providers (PPK) as regulated in Presidential Regulation Number 19 of 2016 concerning the Second Amendment to Presidential Regulation Number 12 of 2013 concerning National Health Insurance (JKN). However, this change still does not provide legal certainty for BPJS patients when problems occur related to the amount of payments that must be paid by BPJS to Health Service Providers, if there are patients who experience/require to be treated with costs that exceed the rates determined by BPJS. Legal consequences if there is no legal certainty for health services
ANALISIS SISTEM PEMBIAYAAN PENDIDIKAN YANG DIKELOLA KEMENTERIAN AGAMA PADA KANTOR WILAYAH KEMENTERIAN AGAMA PROVINSI SUMATERA UTARA
Authors: Wulandari S Tanjung Ayu , Qarni Waizul
Published: March 2022

Penelitian ini bertujuan untuk dapat mengetahui bagaimana sistem pembiayaan pendidikan yang dianalisis melalui renstra Kementerian Agama serta kebijakan keuangan pendidikan. Penelitian yang digunakan adalah penelitian lapangan atau field research dengan menggunakan data yang tersedia di lapangan. Penelitian ini juga menggunakan pendekatan perpustakaan dengan memanfaatkan analisis perencanaan strategis (renstra) Kementerian Agama dan pedoman kebijakan serta landasan hukum keuangan pendidikan. Hasil penelitian ini menjelaskan bahwa dalam pengelolaan pendidikan, pembiayaan merupakan salah satu sumber yang berperan sebagai penunjang efisiensi dan efektivitasnya secara langsung. Dalam Undang-Undang Dasar (UUD) mengenai Sistem Pendidikan Nasional, yang akan memberikan tanggung jawab dalam hal pendanaan pendidikan adalah pemerintah, daerah, serta masyarakat. Disamping itu, Kementerian Agama yang menaungi madrasah maupun universitas juga memiliki sistem pendanaan pendidikan sendiri. Serta diperolah kesimpulkan bahwa sistem pembiayaan pendidikan ini menjadi suatu hal yang sangat penting guna terciptanya distribusi yang adil, merata dan menyeluruh.
Gentrification and vigilantism in Milan’s Central train Station
Authors: Mireanu Manuel
Published: March 2022

Mireanu’s paper studies a far-right vigilante group, City Angels, in Milan, Italy. As he illustrates, the City Angels have helped instigate urban renewal of the city’s Central train Station by targeting marginalized residents living near the station. While these vigilantes are not part of the state, they give the illusion that they are. Their securitization of the central train station then enables the state and real estate developers to enter and gentrify the area.
Film review of ‘PUSH’: A documentary by Fredrik Gertten
Authors: Sartori Caterina
Published: March 2022

Push is a film of great ambition and great skill. Director Fredrik Gertten takes on the global housing crisis, and aims to uncover and expose the systemic forces that increasingly make contemporary cities unaffordable to working and middle class residents. The concept of gentrification no longer seems useful in this quest, and Gertten is looking for a new language to speak of the phenomenon. It is notoriously difficult to make cinematic, gripping films about the inner workings of the economy, and Gertten skilfully uses every trick in the filmmakers’ hat to produce an engaging and relatable work that carries the audience along and makes a complex but digestible argument.
EMPLOYEE ENGAGEMENT STRATEGIES IN INFORMATION TECHNOLOGY COMPANIES
Authors: GOMATHY Dr. C. K.
Published: March 2022

Employee engagement is important in an organization to achieve its goals. Engagement is an employee involvement with an interest in organizational principles. in the company’s business context. Employee engagement refers to working together with their colleagues to get effective tasks performance which leads to getting the productivity of an organization. Employees will perform with a positive attitude towards the organization Every employee will put effort into their work to get a good name for his organization. This research will explain how an employee will put effort into his work and complete their work on time. Employee engagement will help how employee engagement is associated with employee job satisfaction .this research results in many employees coming together and compliance with their organizations which will bring maximum involvement, and in turn, retaining is not impossible. Keywords: Effective employee engagement, Challenges, New trends, IT sector Employee Engagement
Migranti odlaze mržnja ostaje - antimigrantska ekstremna desnica u Srbiji
Authors: Petrovic Predrag , Ignjatijević Marija
Published: March 2022

The extreme right has been present in Serbia since the Socialist Federal Republic of Yugoslavia disintegrated during the war of the 1990s. Its thematic backbone is based on Serbian nationalism and chauvinism, preserving the patriarchal family and opposing same-sex marriage, anti-globalism and strengthening ties with Russia. Migrants were not the topic of extreme right-wingers even during the “migrant crisis” of 2015 and 2016, when about a million refugees passed through Serbia. This changed three years ago, when the right-wing political parties Dveri and Dosta je bilo [Enough is enough] started to scare citizens by telling them that they would become a minority as a result of the mass settlement of migrants in Serbia. A number of extreme right-wing groups accepted this rhetoric, which soon grew into ‘civil arrests’, interception and intimidation of “illegal” migrants. Apart from the immediate consequences, such as harassment and intimidation of migrants, such activities of the extreme right have long-term, less visible consequences for society in Serbia, such as influencing the spread of views and values that are contrary to the democratic order. That is why it is so important to explore who the main actors who create and spread anti-immigrant narratives today are, why they (suddenly) started doing it, and what makes people susceptible to those narratives. It is also important to identify the main anti-immigrant narratives and messages, as well as the mechanisms and channels used by extreme right-wingers to attract attention and spread their influence to a wider audience. To answer these questions, we have conducted 42 interviews and analysed messages the most active far-right groups and individuals posted on social networks in 2021.
ADOLESCENT DIGITAL LITERACY AND ETHICS
Authors: Lubis Rafly Aulia , Sinaga Risky , Fauza Aan
Published: March 2022

Language is a means of communication among individuals. Along with the development of social media, aspects of communication using language are increasingly diverse. This diversity appears according to general agreement in community communication patterns. The tendency to produce new terms is very possible where communities have diverse backgrounds, both educational, economic, family and so on, as factors that produce new languages. This study uses a qualitative approach that presents research on the use of language in social media. The finding shows that new media and adolescence are both seen as something that is taking shape. The instability of these two things has a tendency to be mutually beneficial or even detrimental on the one hand. Early awareness of the characteristics of the new digital ethical world media in relation to adolescent users is expected to reduce the negative excesses of the impact it causes. Hence, literacy and ethics towards new media are the keys for teenagers to be able to enrich their identities and maintain their privacy.
OXIDATION OF DIOLS BY MORPHOLINIUM FLUOROCHROMATE: A KINETIC AND MECHANISTIC STUDY
Authors: Arora Bhawana , Ojha Jitendra , Mishra Pallavi
Published: March 2022

The kinetics of oxidation of diols by morpholinium fluorochromate (MFC) has been studied in dimethyl sulfoxide (DMSO). Corresponding hydroxy carbonyl compounds are the main product of oxidation. The reaction is first order in MFC and follows Michaelis-Menten type of kinetics with respect to diols. The reaction is catalyzed by H+ ions. The hydrogen ion dependence has the form: kobs =a+ b[H+]. Oxidation of deuterated ethylene glycol showed substantial primary kinetic isotopic effect (kH / kD = 5.750 at 298 K). Thermodynamic parameters like enthalpy, entropy and free energy of activation are discussed and validity of the isokinetic relationships also established. We have used nineteen different organic solvents for carrying out our analysis. Taft and Swain’s multiparametric equations have been used for the solvent effect analysis. In our experiments rate constants have showed excellent correlation with Taft's Σσ* values along with negative values for the reaction constant ρ*. A suitable mechanistic pathway for the chromate ester formation has also been suggested.
MINERALOGICAL CHARACTERIZATION OF SEDIMENTS, KALRAYAN HILLS SOUTH INDIA - A FTIR STUDY
Authors: Paramasivam Rajesh , Shanmugam Senthil , Venkidasamy Ramasamy , Shanmugam Arivoli
Published: March 2022

In environmental studies, the mineralogical composition of sediments is an important indicator. In combination with other indicators, they contribute to the understanding of changes in sediment sourcing as well as in weathering and depositional processes. Fourier transform infrared spectroscopy (FT-IR) spectra contain information on mineralogical composition because each mineral has a unique absorption pattern in the mid-IR range. In this study, total of sixty five sediment samples were collected from different locations of the Kalrayanhills, part of Eastern ghats, South India, lies between the north latitudes 11° 36’ and 12° 01’ N and the east longitudes 78° 29’ and 78° 54’ E. Twenty three minerals are identified using FT-IR analysis. Obtained minerals are confirmed by X-ray diffraction (XRD) analysis.The relative distribution of major minerals was determined by calculating extinction co-efficient.
EVALUATION OF PHYTOCHEMICAL SCREENING AND BIOLOGICAL ACTIVITY OF LYOPHILIZED SUGARCANE JUICE, VACUUM AND OPEN PAN JAGGERY FOR AQUEOUS EXTRACTS
Authors: Ahmed Muneer Saif Hasan , M.A. Harish Nayaka , Almulaiky Yaaser Q. , Al-Dalali Sam
Published: March 2022

Lyophilized aqueous extracts of sugarcane juice (SJ), vacuum pan jaggery (VJ), and open pan jaggery (OJ) were estimated for their Physico-chemical properties, phytochemical constituents, and biological activity against certain clinical isolates. The phytochemical results of flavonoid and tannin content indicated high significance in the mean values of the VJ sample whereas, phenol and terpenoid content was significantly higher in the OJ sample. For antioxidant activity, the mean values of IC50 of DPPH assay and ABTS assay showed a highly significant increase for OJ, which were 2.810 and 2.441% respectively. All the aqueous extract showed a zone of inhibition against tested organism extract except Salmonella typhi. Bacillus subtilis, and Pseudomonas aeruginosa. The results indicate that the Lyophilized SJ, VJ and OJ have phytochemical components that can have other clinical and medicinal properties that use these products not only as a food additive but as pharmaceutical additives. Worth a mention that our study constitutes the first research to evaluate vacuum evaporated jaggery product as a potential antioxidant resource to investigate by in vitro trials in cellular systems.
STUDY THE TEMPERATURE EFFECT ON APPARENT MOLAR VOLUMES AND VISCOSITY (JONES DOLE COEFFICIENT) OF MAGNESIUM SULPHATE, ALUMINIUM AMMONIUM SULPHATE AND POTASSIUM ALUMINIUM SULPHATE IN BINARY MIXTURE OF AQUEOUS DMF AND AQUEOUS DMSO
Authors: Raundal Pratibha G. , Sheikh Anis A. , Kasim Sayyed S.
Published: March 2022

The apparent molar volumes (фv) and viscosity B coefficients (Jones Dole)for Magnesium sulphate, Aluminium ammonium sulphate and Potassium aluminium sulphate in aqueous Dimethylformamide (DMF) and aqueous Dimethyl sulphoxide (DMSO) were evaluated from density (ρ) and viscosity (η) at various temperatures as 308.15, 313.15, 318.15 and 323.15K with help of bicapillary pycnometer and Ubbelohde viscometer instruments respectively. The densitydata for all the solutions were analyzed in limiting apparent molar volume (фv°) and experimental slopes (Sv) obtained from Masson equation. The viscosity data of solution were analyzed in term of A and B coefficient obtained from Jone-Dole equation.