bluuebunny/crossref_metadata_2025 huggingface dataset:
Mechanisms of telomere dysfunction in cancer from genomic instability to therapy: A review
Authors: Amir Mohammad Karimi Forood
Published: September 2024

Telomeres are critical nucleoprotein structures that safeguard chromosome ends from degradation and fusion, thereby ensuring genomic stability. Without proper maintenance, telomeres progressively shorten with each cell division, leading to dysfunction and triggering chromosomal instability. This dysfunction is a significant driver of tumorigenesis, primarily by facilitating genetic alterations such as aneuploidy, gene amplifications, and chromosomal rearrangements. Cancer cells bypass cellular aging by activating mechanisms like telomerase reactivation or the Alternative Lengthening of Telomeres (ALT) pathway to maintain telomere length. This review explores the mechanisms by which telomere dysfunction contributes to genomic instability and cancer progression, including telomere shortening, breakage-fusion-bridge (B/F/B) cycles, and the ALT pathway. Additionally, it addresses the therapeutic potential of targeting telomere maintenance, highlighting current strategies like telomerase and ALT inhibitors. However, developing telomere-based therapies presents challenges, including resistance mechanisms, off-target effects, and potential impacts on normal stem cells. Emerging research areas such as the development of biomarkers and combination therapies offer promising directions for overcoming these challenges. Understanding telomere dynamics provides novel opportunities to exploit cancer cell vulnerabilities and advance treatment strategies.
The possibilities for cultural entrepreneurship in Eleusis as the European capital of culture
Authors: Fotini Maniou  , Roidο Mitoula  , Kostakis Ioannis
Published: September 2024

The institution of the European Capital of Culture was established in 1985 and is one of the most important cultural events in Europe, contributing to the sustainable development of cities and their surrounding areas. Elefsina decided to compete for the title of European Capital of Culture for the year 2023 and transformed into a dynamic cultural center with positive impacts on the quality of life of its citizens and new development opportunities in the region The aim of this study is to present Eleusis as the European Capital of Culture for 2023, highlighting the monuments that can attract today's visitors and lay the foundations and prospects for local development within the framework of cultural entrepreneurship. The impressions of the local community, the impact it has left, and more broadly the interest and reception of events, as well as the views of visitors on the contribution of the institution to local development, are examined through the collection of 320 questionnaires in December 2023.
Dabur Chyawankidz Gummies: A novel dosage form for immunomodulation
Authors: Baidyanath Mishra  , Dharmendra Kumar  , Ruchi Srivastava  , Varun Kumar Singh  , Yathapu Srinivasa Reddy  , Apratim Sai Rajesh
Published: September 2024

Across age groups, a tasty eatable product is always cherished and so is immunity on the other hand, equally indispensable throughout lifetime. Optimal and sustained immunity is a contiguous requirement for growth and welfare of the body and goodness of herbs of Chyawanprash is a time-tested formula in Ayurveda for a healthy life. Combining the innovation of a chewable system of drug delivery with goodness of Ayurveda, Dabur India Limited has prepared the Dabur ChyawanKidz Gummies – a palatable, chewable and immune boosting formulation. To assess its efficacy, the active immune boosting formulation of the product were studied for its activity on NK Cell, Cytokines (TNF-α) and phagocytosis by Macrophages; wherein compared to the control groups, the test product showed up to 49% increased NK Cell activity, 66-fold increase in TNF-α (Cytokines) and 55% increased phagocytic activity by macrophages. The result indicates 3x (triple) immunity action of the Dabur ChyawanKidz Gummies, making it a unique choice of chewable immunomodulatory preparation, which appeals across ages, combining taste with immunity.
Tinea capitis with kerion complicated by keloid formation in a 34-year-old man: A case report
Authors: Ekeh Nnamdi  , Lawan Habeebah  , Emenikeonu Adanna  , Njoku Chidimma  , Agu Evelyn
Published: September 2024

A kerion, also known as a dermatophyte, is a type of inflammatory tinea capitis caused by an exaggerated immune response to a fungal ringworm infection primarily affecting the scalp. A keloid is an abnormal scar tissue proliferation occurring at the site of tissue injury or spontaneously. It occurs more commonly in darker-skinned individuals. The coexistence of kerion and keloid is rare. This case involves a 34-year-old man who presented with a four-year history of scalp swelling, itching, and occasional fluid discharge. There is a history of keloids in multiple parts of the body. Examination revealed multiple keloids on the scalp alongside a purulent, oozing rash with satellite nodules. Skin scraping for KOH microscopy was positive for fungal spores and hyphae. This case highlights the rare complication of keloid formation in kerion which can hinder effective treatment of the underlying fungal infection.
In-silico analysis of ethanol peel extract of Citrus sinensis on mercury chloride-induced prefrontal cortex damage in Wistar rat
Authors: Okafor Ifeanyi Fidelis  , Awuzie, Ifechukwu Milicent
Published: September 2024

This study evaluated the effect of ethanolic extract of Citrus sinensis peel on mercury chloride-induced changes in the prefrontal cortex of adult Wistar rats. Twenty-five Wistar rats were purchased and divided into five groups containing five animals in each group. Group 1 was administered with distilled water, Group 2, Group 3, Group 4, and Group 5 were administered with 5 mg/kg of mercury chloride only, 5 mg/kg of mercury chloride and 140 mg/kg Silymarin, 5 mg/kg mercury chloride and 1000 mg/kg of ethanoic extract of orange peel, and 5 mg/kg mercury chloride and 1500 mg/kg of ethanoic extract of orange peel. All administration was done orally and the administration lasted for 14 days. The animals were sacrificed humanely using 75 mg/kg ketamine intraperitoneally and prefrontal was dissected out. Part was homogenized in 0.1M phosphate buffered saline for the estimation of superoxide dismutase (SOD), and catalase (CAT) activities, and Malondialdehyde (MDA) level and the other part was fixed by immersion in 10 neutral buffered formal-saline for histological evaluation. The chemical structure of sixteen compounds from Citrus sinensis peel obtained from GC-MS analysis reported in the literature were retrieved from the PubChem compound database and the crystal structure of human peroxisome proliferator- activated receptor gamma (PPARγ; PDB:ID: 2P4Y) reported to increase the expression of catalase gene, human extracellular copper-zinc superoxide dismutase enzyme (PDB ID: 2JLP) and mammalian 15-lipoxygenase - 1 enzyme (PDB ID: 2P0M) responsible for the production of lipid peroxidation were retrieved from the PDB database. Ligands and protein preparation, docking and MM-GBSA relative binding free energy calculation were done in Maestro 2023.1. Data obtained was analyzed using the IBM SPSS (version 25) using one-way ANOVA and p-value < 0.05 was considered statistically significant. The results indicate that the MDA level in control Group(13.29±1.183 μmol) is statistically significantly lower compared to the Group 2 (21.88±1.96 μmol), group 3 (27.44±3.52 μmol), Group 4 (22.20±1.16 μmol) and Group 5 (25.40±3.13 μmol). No statistically significant difference was observed in SOD activity. The CAT activities in control group (53.51±6.83 nmol/ml) was statistically significantly lower compared to the group 2 (26.21±3.70 nmol/ml), Group 3 (27.17±5.32 nmol/ml), Group 4 (25.30±4.24 nmol/ml) and Group5 (26.59±4.22 nmol/ml).The present study suggests, ethanolic extract of Citrus sinensis peel have protective effects on mercury-induced changes in prelimbic part of the prefrontal cortex of adult Wistar rats.
Investigation of differences in a new electronic test to detect working memory deficits of students with and without learning difficulties of secondary school
Authors: E Dimitriou  , A Ekonomou  , P Roussos  , A Drigas
Published: September 2024

The term "working memory" refers to our ability to retain and manipulate information in our minds for short periods. Recent research has linked its function to school performance, and it is strongly supported that deficits in working memory hinder the learning of some students, who are likely to face significant learning difficulties in both primary and secondary education. The purpose of this study is to investigate the differences in working memory functions of secondary school students with and without learning difficulties through the administration of a new electronic test developed for this purpose. A total of 262 secondary school students, 217 without learning difficulties and 45 with learning difficulties, who attended schools in Athens participated in the survey. The results showed that students with learning difficulties performed significantly worse on the tests than students without learning difficulties. The reliability and validity tests showed that the developed test is a valid and reliable tool.
Unlocking the Power of Intellectual Capital: Will it Increase the Entity Value?
Authors: Nurrahmawati An , Chayati Nur , Aini Annisa Qurrota , Widarjo Wahyu
Published: September 2024

This research examines the relationships between Intellectual Capital, Human Capital, Structural Capital, and Relationship Capital toward Firm Value in Indonesia's property and real estate companies. The aim is to analyse the power of intellectual capital in leveraging business performance. The target population for the study constituted all property and real estate sector companies in Indonesia total 215 observations within 2018-2022. The data was processed using an ordinary least square approach to gain the t-value of this relationship. This research measures the intellectual capital variable not from a financial or value-added perspective but from a descriptive side using for-way coding indicator. We found that relational capital has a significant positive relationship toward firm value. The study emphasized the need to change the proxy for firm value or to add some bridge between intellectual capital and financial performance to create a clear understanding.
KAJIAN BANJIR PESISIR MENGGUNAKAN MODEL DELFT3D STUDI KASUS WILAYAH SERAM BAGIAN TIMUR
Authors: Damayanto Moch. Zainuri , Tubalawony Simon , Noya Yunita A
Published: September 2024

The northern coastal area of eastern Seram is a region prone to flood disasters, especially those caused by sea level rise or tidal flooding. The coastal flood case that occurred on February 22, 2022, in the eastern Seram region resulted in significant losses. In order to reduce material losses and improve the accuracy of early warning systems for coastal floods, a more in-depth identification of coastal flooding in the area is necessary. This study integrated the DELFT3D model with flood mapping using change detection and threshold methods to obtain the characteristics of tidal fluctuations and flood distribution in the case study on February 22, 2022. Water level observation data from the National Geospatial Information Agency (BIG) were used to validate the model results. The analysis showed that the DELFT3D model had a high correlation with the BIG observation data, with a correlation value of 0.98 and an RMSE value of 0.11. The flood-prone areas were found to be distributed along the eastern Seram coastline. The DELFT3D model also successfully predicted the water level during coastal floods with adequate accuracy. These results can be used to develop disaster mitigation strategies and improve the accuracy of early warning systems for coastal floods in the eastern Seram region.
 
ABSTRAK
Wilayah pesisir utara Seram Bagian Timur merupakan wilayah yang rawan terjadi bencana banjir yang diakibatkan adanya kenaikan muka air laut atau ROB. Kasus banjir pesisir yang terjadi pada tanggal 22 Februari 2022 di wilayah Seram Bagian Timur telah menimbulkan kerugian yang signifikan. Dalam rangka mengurangi kerugian materi dan meningkatkan akurasi peringatan dini banjir pesisir, perlu dilakukan identifikasi yang lebih mendalam terkait terjadinya banjir pesisir di wilayah tersebut. Dalam penelitian ini, dilakukan integrasi antara model DELFT3D dan pemetaan wilayah banjir menggunakan metode deteksi perubahan (change detection) dan ambang batas (threshold) untuk mendapatkan karakteristik pasang surut dan sebaran banjir pada studi kasus tanggal 22 Februari 2022. Data pengamatan water level dari Badan Informasi Geospasial (BIG) digunakan untuk memvalidasi hasil model. Hasil analisis menunjukkan bahwa model DELFT3D memiliki korelasi yang tinggi dengan data pengamatan BIG, dengan nilai korelasi sebesar 0,98 dan nilai RMSE sebesar 0,11 serta wilayah terjadinya banjir menyebar sepanjang pesisir Seram Bagian Timur. Pemodelan DELFT3D juga berhasil memprediksi tinggi muka air selama banjir pesisir dengan akurasi yang memadai. Hasil ini dapat digunakan untuk mengembangkan strategi mitigasi bencana dan peningkatan akurasi peringatan dini banjir pesisir di wilayah Seram Bagian Timur.
Kata Kunci: Pemodelan, DELFT3D, banjir rob, wilayah pesisir, tinggi muka air laut
A Guerra Global ao Terror para além dos casos tradicionais: uma análise das operações norte-americanas de contraterrorismo
Authors: Bernussi Mariana
Published: September 2024

Este artigo procura abordar a guerra global ao terror como uma guerra duradoura, a partir de casos não tradicionais e frequentemente negligenciados pela literatura, como países do Sahel e do Chifre da África. Os governos norte-americanos, desde 2001, têm adotado simultaneamente um conjunto de estratégias contraterroristas que contribuíram para a permanência e dilatação da guerra global ao terror, e que serão tratadas em sintonia aos casos pré-citados, a partir da adoção da Autorização para o Uso da Força Militar, que possibilitou o estabelecimento de parcerias estratégicas com diversos países estrangeiros e suas forças locais. O artigo busca mostrar, a partir de documentos do Departamento de Estado norte-americano, sua recorrência como política de Estado norte-americana de 2001 a 2020. Ainda que existam algumas variações no tratamento da questão de um governo para o outro, o artigo procura construir o argumento de que a estrutura e o arcabouço da guerra global ao terror não se alteram, fazendo dessa uma guerra duradoura.
Republicanismo e a Revolução Haitiana
Authors: Meira Kelly Cristine Oliveira
Published: September 2024

A Revolução Haitiana foi uma dentre várias revoluções ocorridas no século 19, entre elas a Revolução Estadunidense e a Francesa e que tinham na linguagem de suas narrativas o princípio da liberdade e por isso podem ser compreendidas sob a perspectiva do Republicanismo. É indispensável destacar que, ao contrário dos outros movimentos de independência, a Revolução Haitiana foi o resultado de uma insurreição de escravizados, o que por si só já confere um caráter único a ela. Ademais, a Constituição Haitiana de 1805 também é considerada como a “mais radical do Novo Mundo”. Assim, o objetivo deste artigo é apresentar um panorama da história da Revolução Haitiana sob o prisma do Republicanismo e destacando a importância da população originária do continente africano.
Lendo a In/Segurança Internacional em lugares dissonantes: imaginários racializados no cotidiano na Lapa, Rio de Janeiro
Authors: Valdivia Maria Lidia Mattos , Cunha Brunno Victor Freitas
Published: September 2024

O presente artigo explora as dinâmicas de in/segurança no campo de Estudos de In/Segurança Internacional a partir de uma analítica sensível às redes múltiplas de relações, agentes, práticas e objetos que constituem discursos sobre a alteridade racial e informam processos de racialização. Para tal, a partir de revisão de literatura de fontes secundárias, realizamos uma revisão crítica dos Estudos de In/Segurança clássicos e críticos, de modo a evidenciar seus pressupostos racializados, e oferecer maneiras mais complexas de observar como as práticas de in/segurança emergem a partir de relações cotidianas. Em um segundo momento, construímos uma analítica de in/segurança racial a partir de noções de raça como significante deslizante, de ambivalência do discurso racial e de gênero e da complexificação da manifestação da violência a partir de relações simultâneas de proximidade e distanciamento. A partir disso, analisamos as dinâmicas de revitalização e pacificação da Lapa, Rio de Janeiro, para evidenciar as ambiguidades da in/segurança no cotidiano. Trazendo as experiências de mulheres travestis na Lapa neste contexto, demonstramos tanto o imaginário racializado subscrito às manifestações de violência por elas sofridas quanto as ambiguidades de sentir-se in/seguro neste espaço.
O Outro interno odiado: racismo e (in)segurança ontológica nos discursos da política externa brasileira
Authors: Jardim Camila Amorim
Published: September 2024

A partir de diálogos mais aprofundados entre a política externa brasileira (PEB) e lentes analíticas pós-estruturalistas (principalmente inspiradas pela psicanálise lacaniana) e pós-coloniais, bem como tendo em vista a lacuna em torno de temas de raça e racismo nos estudos da PEB, este trabalho busca posicionar a questão racial, especialmente o mito da democracia racial, como o verdadeiro alicerce das leituras da identidade brasileira, bem como dos cálculos de preferências e interesses de suas elites. Entendendo “política externa” como uma prática discursiva de construção de fronteiras, o conceito de (in)segurança ontológica é central neste artigo. Privadas do status de cidadãs, as populações negras e indígenas foram (e são) excluídas das narrativas identitárias que definem quem e para quem é o Brasil, de modo que a estabilidade da identidade do brasileiro prevê, necessariamente, a insegurança ontológica (e todas as violências que a ela acompanham) de grande parte da população que habita em seu território. Ao mesmo tempo, faz-se necessário interrogar as condições de possibilidade que permitem, de forma ambígua, que sejam sustentados discursos de Política Externa que afirmam exatamente o contrário, dando centralidade ao componente racial negro e indígena na identidade (inter)nacional do país, mascarando o encarceramento em massa e o genocídio aos quais essas populações são submetidas.
A União de Paris revisitada
Authors: Malavota Leandro Miranda , Martins Mônica de Souza Nunes
Published: September 2024

O presente artigo apresenta resultados parciais de uma pesquisa em andamento, elegendo como objeto o processo de adesão do Brasil a um sistema internacional de regulação e governança dos direitos de propriedade industrial, fundado em 1883. Partindo-se de uma reflexão sobre as relações entre a apropriação tecnológica e o desenvolvimento capitalista na segunda metade do Oitocentos, o estudo procura investigar os motivos, objetivos e circunstâncias que levaram o Império da Brasil a aderir prontamente à Convenção da União de Paris para a Proteção da Propriedade Industrial, primeiro acordo multilateral sobre a matéria, antecipando-se a vários países industrializados e tecnologicamente avançados. Conclui-se que a adesão do Brasil ao acordo atendeu às demandas de segmentos produtivos interessados na adoção de novos padrões de proteção à propriedade tecnológica no país e integrou-se a uma nova estratégia de política externa lançada nos anos 1870.
Da Fronteira ao Litoral: a Dinâmica Terrestre do Narcotráfico de Cocaína no Brasil em 2022
Authors: Rodrigues Lucas Barreto , Franchi Tássio , Paiva Ana Luíza Bravo e
Published: September 2024

O objetivo deste artigo é comparar a dinâmica geográfica do narcotráfico de cocaína por vias terrestres no Brasil na primeira metade do ano de 2022 com estudos que haviam descrito o mesmo fenômeno em outros momentos, a fim de atestar a continuidade dos padrões de deslocamento ou não. Para tanto, apresenta-se a dinâmica das rotas de narcotráfico de cocaína dentro do Brasil, pautada por características como: modal predominante por região e infraestrutura de transportes, concentração populacional, tipo de terreno, e interesses dos narcotraficantes locais. Tal classificação é realizada com base nos textos de autores da geografia, como Lia Osório Machado e Aiala Colares Couto, e relatórios de investigação pública/notícias da Polícia Rodoviária Federal brasileira disponíveis na plataforma gov.br. O trabalho sugere as diferenças entre as rotas que passam pela fronteira brasileira na Amazônia e Centro-sul do país para, a partir disso, focando nas rotas que ingressam pelo centro-sul, verificar se há diferenças entre as conclusões dos autores previamente citados e os dados coletados. Por fim, os cenários construídos a partir das informações da Polícia Rodoviária Federal e os períodos temporais estudados pelos autores, apresentam pouca diferença, sendo, na prática, uma confirmação de que os trabalhos de mapeamento das rotas observados pelos autores seguem sendo descrições da dinâmica de narcotráfico recente.
O O Sionismo Evangélico e o apoio dos EUA a Israel durante o Governo Donald Trump
Authors: Oliveira Flavio Rocha de , Corrêa Matheus Felipe
Published: September 2024

Em seu mandato, Donald Trump executou uma Política Externa fortemente pró-Israel. Parte relevante desse êxito pode ser atribuída à influência religiosa evangélica em seu governo. Este trabalho propõe uma análise da relação entre os seguintes atores: Estados Unidos, Governo Trump, evangélicos norte-americanos e o lobby pró-Israel; as justificativas da teologia protestante no apoio ao Estado de Israel e a maneira com que a sintonia desses atores proporcionou um avanço diplomático israelense pouco visto no presente século. Foi usado como referência o período entre 2017 e 2020. A conclusão do trabalho é de que a sintonia entre esses atores, aliada ao pragmatismo esperado do Estado de Israel, culminou em um modus operandi que favoreceu simultaneamente a atuação política de Tel-Aviv e um avanço significativo na agenda da direita cristã estadunidense.
O Negacionismo Antivacina e o Alinhamento nos Discursos de Malafaia e Bolsonaro Frente à Pandemia de COVID-19 no Brasil
Authors: Dias Kelvin Araújo da Nóbrega , Nobre Fábio Rodrigo Ferreira
Published: September 2024

Este trabalho parte do pressuposto de que os discursos negacionistas, por parte de líderes religiosos, vão ao encontro das posturas da gestão Bolsonaro. Em meio ao conservadorismo político, esses atos de fala representam um fator relevante no movimento antivacina e na hesitação vacinal no Brasil. Dessa forma, trata-se de um estudo de caso, com o objetivo de analisar criticamente os discursos de Silas Malafaia e sua concordância narrativa com Bolsonaro. Para tal, foram utilizadas a Análise Crítica de Discurso (ACD) tridimensional e Análise De Discurso Textualmente Orientada (ADTO), teorizadas por Fairclough. Os eventos discursivos analisados são do ano de 2021. Não obstante, é contextualizado a formação histórica do conceito “religião” e sua relação com o Estado moderno. Ainda, explica-se o contexto pandêmico brasileiro e o negacionismo. Conclui-se que houve um alinhamento entre as falas de Malafaia e Bolsonaro em direção oposta às orientações da comunidade científica internacional. Ademais, as narrativas apontam para a construção de uma identidade coletiva baseada no nacionalismo religioso. Além disso, as reflexões e ferramentas de Fairclough se mostram relevantes para uma compreensão menos difusa dos fenômenos sociais, além de evidenciar relações de poder que podem estar presentes de maneira subliminar nos discursos hegemônicos.
Racismos e antirracismos nas/para as Relações Internacionais
Authors: Castro Luciano Rodrigues , Lopes Rafael Bittencourt Rodrigues
Published: September 2024

Apresentação do Dossiê Racismos e antirracismos nas/para as Relações Internacionais
Pengaruh E-System Pajak, Self Assessment dan Pemahaman Perpajakan Terhadap Kepatuhan Wajib Pajak Orang Pribadi
Authors: Zinny Haffiz , Ahmad Afridian Wirahadi , Zerma Desi Handayani
Published: September 2024

This research aims to examine the influence of the tax e-system, self-assessment, and tax understanding on the compliance of individual taxpayers who own restaurant businesses in the city of Padang. Data collection method for this research involves primary data by distributing questionnaires directly to the respondents. The population in this study consists of all restaurant taxpayers in Padang who are registered with BAPENDA Padang. The sampling technique used is simple random sampling with a 10% error rate according to the Slovin formula. The sample in this study consists of 83 individual taxpayers who own restaurant businesses. The data analysis method employed is multiple linear regression. The results of this study indicate that the tax e-system and self-assessment have an influence on the compliance of individual taxpayers. However, tax understanding does not have an influence on the compliance of individual taxpayers.
Narrativa feminista
Authors: Touton Isabelle
Published: September 2024

The feminist gaze has permeated postcrisis fiction by women in Spain. In the first part, this chapter explores the ongoing and necessary fight for bodily autonomy, analyzing it through the lens of vulnerability and the poetics of the obscene. The second part shifts focus to the exposure of structural violence, made visible through narratives that juxtapose the period before and after the emergence of feminist consciousness. Finally, the chapter underscores the struggle for a form and language free from the constraints of ‘the master’s voice’.
Ideología lingüística e identidad nacional en tríptico de Marta Rojals
Authors: Ojeda Caba Júlia
Published: September 2024

This chapter examines key cultural, political, and literary issues intertwined within the postcrisis Catalan context. Through a detailed study of Marta Rojals’ novels, it offers a cross-analysis of formal literary elements with concepts from sociolinguistic studies and the framework surrounding the Normalització pujolista project and its connection to the culture of Spain’s Transition to democracy. The chapter sheds new light on some of the most prominent social and political conflicts in contemporary Catalonia since the collapse of the real estate bubble and the onset of the Catalan independence movement. Simultaneously, the author seeks to identify the elements driving the re-politicization of current Catalan narrative, considering factors such as linguistic conflict, national identity, and gender. The chapter also expands the understanding of what can be considered political in other literatures of the Spanish State.
Nuevas voces para el viejo conflicto, viejos conflictos para el nuevo mundo
Authors: Azpeitia Lorea , Rodríguez Eider
Published: September 2024

This chapter reflects on how the Basque conflict has shaped the corpus of contemporary Basque literature from 1976 to the present, with particular focus on the impact of social changes, such as feminism, and aesthetic developments. It identifies two main stages: the period from 1976 to 2000 and the period from 2001 to 2023. The chapter analyzes five representative Basque novels of the twenty-first century: Joseba Sarrionandia’s Lagun izoztua (2001), Juanjo Olasagarre’s Ezinezko maletak (2008), Lander Garro’s Gerra txikia (2014), Uxue Alberdi’s Jenisjoplin (2017), and Karmele Jaio’s Aitaren etxea (2019).
Desplazamientos de lo político
Del conflicto armado a los discursos feministas
Authors: Egaña Etxeberria Ibon
Published: September 2024

This chapter outlines what has been understood as the political novel in Basque literature in recent years, focusing on narrative works published during the postcrisis. Reading the Basque novels of this period, the author examines the different forms of politicization that have intersected with this narrative, defining the roles that national conflict, feminism, and social class have played in this literary production. The chapter questions the extent to which the novel about the Basque conflict remains political today. At the same time, it argues that feminism has permeated and transformed the Basque literary field over the last decade.
PENGARUH PEMBERIAN KUNYIT ASAM TERHADAP PENURUNAN NYERI DYSMENORRHEA PRIMER
Authors: Puspita Nara Lintan Mega , Fitriasnani Meirna Eka , Saputri Ihrom Fatma , Nugrohowidi Agung
Published: September 2024

Abstrak
Dysmenorrhea adalah rasa nyeri selama menstruasi yang ditandai dengan rasa kram diperut bawah.  Tujuan penelitian ini  adalah untuk mengetahui ada Pengaruh Pemberian kunyit asam terhadap Dysmenorrhea pada mahasiswa  Sarjana Kebidanan di Fakultas Ilmu Kesehatan Universitas Kadiri.
Rancangan penelirian ini adalah Pre Eksperimen dengan menggunakan metode one group pre test – post test desain. Jumlah sampel dalam penelitian ini adalah 16 responden diambil dengan menggunakan teknik purposive sampling, penilaian  skala  numerik   sebelum   dan   sesudah   diberikan  perlakuan.   Hasil penelitian ini di analisa dengan menggunakan uji statistic wilcoxon.
Berdasarkan uji wilcoxon ada pengaruh pemberian kunyit asam pada mahasiswa Sarjana Kebidanan di Fakultas Ilmu Kesehatan Universitas Kadiri  Berdasarkan  hasil  penelitian  diatas  diharapkan  bagi  mahasiswa  yang mengalami Dysmenorrhea dapat diberikan salah satu perlakuan berupa pemberian kunyit asam atau air kelapa hijau terhadap Dysmenorrhea.
 
Kata kunci : Kunyit Asam, Menstruasi, Dysmenorrhea
Faktor Utama Keterlambatan Pembayaran Dalam Proyek Perumahan Subsidi dan Komersial
Authors: Verel Bunga Olivia , Milyardi Roi , Lesmana Cindrawaty
Published: September 2024

In the implementation of housing development, the problem of late payment delays is a common issue encountered in commercial and subsidized housing projects during construction. These delays impact the timely completion and lead to disputes among the involved parties, which include owners, contractors, and subcontractors. This study aims to analyze the primary factors contributing to late payment in construction projects, specifically in commercial and subsidized housing. The analysis is conducted from the perspective of the owner, contractors, and subcontractors. The study involves six owner respondents, six contractor respondents, and four subcontractor respondents. The survey results were analyzed using the Analytical Hierarchy Process (AHP) to assess the significance of various factors influencing payment delays in both housing schemes. The analysis results indicate that financial issues with the owner's company are crucial factors from the owner's perspective in causing payment delays in both commercial and subsidized housing projects. A major challenge faced by contractors is the lack of capital availability, which can lead to delays that affect all involved parties. Meanwhile, discrepancies between job specifications not following the contract from the subcontractor's viewpoint highlight the importance of clear communication and rigorousness. All parties involved in housing projects need to improve financial management, enhance capital procurement, and tighten the supervision of contract implementation. By identifying key factors, adopting best practices can help mitigate the risk of payment delays and improve efficiency in future housing project implementations, whether commercial or subsidized.
Evaluasi Pengelolaan Sampah Menggunakan Climate Resilient and Inclusive Cities (CRIC) Waste Assessment Tool Kota Palembang
Authors: Alfansyah M Audito , Fitriani Heni , Hadinata Febrian
Published: September 2024

Waste is a problem that cannot be ignored because it is always generated in all aspects of life. The Climate Resilient and Inclusive Cities CRIC Waste Assessment Tool helps in analyzing the current situation in the city and provides important and practical recommendations from both technical aspects, governance, and social issues. The research aims to evaluate urban waste management using the Climate Resilient and Inclusive Cities (CRIC) Waste Assessment Tool based on management technology in Palembang City. A quantitative strategy was used in this research, along with a descriptive and verification research method. Secondary data is taken from the national waste management information system and other literature to fill in the CRIC Waste Assessment Tool application. Data analysis using CRIC Tool covers waste management, governance, economy and knowledge of citizens, GHG emissions. The results of measuring waste management performance with CRIC show that waste management in the city is still low, most of the waste is disposed of uncontrollably, resulting in SLCPs. Waste banks and TPS3R are still lacking. Achievement of waste management to reduce greenhouse gas emissions has only reached 50% of the recommended target. Proper waste handling is still lacking, such as reduced dumping, open burning, and better composting practices. This will support modifications in waste handling from the community, which can support waste management technology development.
Optimasi Human Error pada Proses Produksi Air Minum Dalam Kemasan di PT. Telaga Tanjung Pomosda Nganjuk
Authors: Irawan Putut Ade , Lukmandono Lukmandono
Published: September 2024

PT. Telaga Tanjung Pomosda, a bottled mineral water manufacturer in Nganjuk, East Java, faces challenges in maintaining high production standards and addressing operational issues such as product rejection and production process errors, impacting overall company efficiency and reputation. This study identifies operational error factors and evaluates the effectiveness of improvement methods. Research procedures utilize HTA, SHERPA, and Poka-Yoke to identify and reduce human errors in bottled mineral water production at PT. Telaga Tanjung Pomosda Nganjuk, focusing on error analysis, probability assessment, and Poka-Yoke strategy implementation. The bottled water packaging process involves critical stages such as cup packaging, pressing, and packing. Errors in each stage can result in delays, decreased water volume, imperfectly pressed lids, and packing mistakes, hindering the entire production process. Research at PT. Telaga Tanjung Pomosda identifies operator issues in machine settings, water measurement, lid positioning, task interruptions, packaging, and cup positioning, with solutions including routine checks and training to enhance product quality
Pengendalian Kualitas Proses Produksi Komponen Automotive di Industri Manufaktur dengan Pendekatan Six Sigma
Authors: Supriyati Supriyati , Widyatri Hasyrani
Published: September 2024

Indonesia's manufacturing sector, which accounts for 18.67% of GDP, faces major challenges in terms of innovation and poverty. PT. XYZ, which produces automotive components using the Injection process, needs to improve product quality to reduce defects in the front cover panel. This study aims to overcome these problems by improving the cooling system, controlling machine parameters, and maintaining material viscosity, while ensuring quality standards through regular maintenance and training. This study uses the DMAIC approach to analyze product quality. Starting with a Baseline to assess Overall Equipment Effectiveness (OEE) and quality ratios, variations in DPMO and quality factors were found. The Define phase identifies key defects, Measure shows improvements over time, Analyzes using Fault Tree Analysis to find solutions, Improves implementation of improvements, and Controls the incorporation of machine parameters to maintain consistency and quality. The research results show large variations in Quality Ratio and Availability, indicating the need to improve OEE which currently ranges from 82.80% to 92.60%. With a total annual production of 345,842 units and 20,538 defective units, the focus of improvements should be on engine and cooling system parameters. This research enriches understanding of product quality models and analysis.
Analisis Kausalitas antara Kualitas Produk, Kualitas Pelayanan, dan Loyalitas Pelanggan di PT. FIFGROUP
Authors: Qowiyah Al Zahro Yayang Qowiyah Al Zahro , Nurfida Anita , Fatoni Fatoni
Published: September 2024

In the digital era, FIFGROUP must meet customer expectations with fast service. This study analyzes the impact of service complaints on customer loyalty using Smart PLS and Fishbone Diagram for identifying key factors. The research employs a quantitative design with a survey approach to assess the impact of product and service quality on Spektra customer loyalty at FIFGROUP. Utilizing a sample of 100 respondents from Kranggan Cibubur, the study gathers in-depth data through questionnaires and observations. The research procedure involves a two-way model to analyze variable relationships, validity, reliability, and mediation effects, with Fishbone Diagram for identifying and prioritizing main problem causes at FIFGROUP. Improvement in product quality (coefficient 0.261; T-statistic 2.902) and service (coefficient 0.206; T-statistic 2.070) at Spektra FIFGROUP significantly enhances customer loyalty. Resource optimization and service digitalization are crucial for long-term effectiveness.
COVİD-19 SALGINI DÖNEMİNDE KİRACI TAHLİYELERİ İLE İLGİLİ OLARAK ABD'DE UYGULANAN POLİTİKALARIN DEĞERLENDİRİLMESİ
Authors: Doğan Adnan Coşkun
Published: September 2024

Covid 19 salgını hayatın her alanında olumsuz etkiler yaratmıştır. Salgın hayatın ekonomik, sosyal ve politik alanlardaki yansımaları devam etmektedir. Ekonomi içerisinde önemli bir sektör olan konut sektörü de salgından olumsuz etkilenmiştir. Kiracılar salgının daha da ağırlaştırdığı konut krizinin en önde gelen mağdurları arasında yer almıştır. Diğer ülkeler gibi ABD’de salgın ortamında konut krizi ile mücadele etmiştir. Dünya ekonomisinin önemli aktörleri arasında yer alan ABD’nin Covid-19 salgını esnasında yaşanan kiralık konut krizi ve bununla bağlantılı tahliye moratoryumlarına ilişkin uyguladığı politikalar ve bunların sonuçları çalışmanın konusunu oluşturmaktadır. Çalışmada salgın sırasında ABD’nin yaşadığı konut krizi deneyimini ele alan literatürde yer alan tespitlerden ve resmi kurumların verilerinden faydalanılmıştır. Çalışma sonucunda salgın sırasında ABD’de yaşanan Covid-19 salgını kaynaklı kiralık konut sorununun çözümünde kısa vadede kira desteği gibi doğrudan yardım politikalarının uygulandığı; uygun fiyatlı kiralık konut arzını artırılması gibi politikaların ise uzun vadeli çözüm olarak ön plana çıktığı tespitlerine yer verilmiştir.
El Palacio de Deportes de Oviedo (1961-1975) en el siglo XXI. La recuperación del sueño de Ildefonso Sánchez del Río
Authors: Adams Carmen
Published: September 2024

El Palacio de Deportes de Oviedo (1961-1975) es una de las más impresionantes obras de ingeniería del siglo XX en España. En 2023, se acometió una gran intervención para rehabilitar el inmueble y adecuarlo a las necesidades del siglo XXI tanto en lo referente a cuestiones funcionales como a sostenibilidad. Se analizan en este trabajo tanto la importancia del proyecto del ingeniero Ildefonso Sánchez del Río como los planteamientos del proyecto restaurador, y la apuesta por recuperar propuestas del autor que en su momento no fueron viables, como la cubierta metálica. Asimismo, se da cuenta de las muchas reparaciones y reformas sufridas por el inmueble a lo largo de los años.
THE CONCEPT OF THE FORMATION THE ELECTRONIC DEMOCRACY AS A TOOL OF REGIONAL PUBLIC ADMINISTRATION
Authors: Orlovska Yulia , Larionova Kateryna
Published: September 2024

The article proposes a conceptual model of regional electronic democracy as a cognitive scheme for the analysis of this tool of local public administration in Ukraine. It is noted that the local levels of the implementation of electronic democracy are theoretically capable of demonstrating the greatest effectiveness of using this tool, as they are related to the immediate environment of everyday life of citizens and relate to solving urgent problems of community residents. The author emphasizes the predominant research interest in e-democracy at the national level and insufficient attention to regional features of e-democracy.
The key role of digital participation in the formation and development of electronic democracy is argued. The author examines various scientific approaches to considering the forms and levels of public participation in regional public administration and supports the conclusion that there is a tendency to expand the meaningful characteristics of participation in administration and the arsenal of electronic tools for its implementation
Using the analytical method and the method of theoretical generalization, the author analyzes the functioning of electronic democracy at the local level. For formulating her own concept, the author relies on the theoretical work of foreign e-democracy researchers, in particular, the concept of invited and invented public space and the classification of types of e-democracy. The model of regional e-democracy is defined as a set of types of electronic participation of the citizens in governance and e-democracy tools as electronic means of implementing this participation. Forms of participation and their corresponding e-tools are grouped into three blocks: transparent e-democracy, deliberative e-democracy and participatory e-democracy.
The author draws attention to the heterogeneity of the public sphere as a place for the implementation of local electronic democracy and claims that the identification of the invented space as a place for the implementation of civil self-organization contributes to a deeper understanding of the modern processes of transformation of public administration under the influence of information and communication technologies. The importance of taking into account the social context and the possibilities of technological support for evaluating the effectiveness of the processes of local democracy is emphasized.
FEATURES OF THE GREEN COURSE IMPLEMENTATION IN EU COUNTRIES USING THE EXAMPLES OF ROMANIA AND POLAND: LESSONS FOR UKRAINE
Authors: Hlushchenko Anna
Published: September 2024

The article examines the peculiarities of the implementation of the Green Course in the countries of the European Union on the example of Romania and Poland. The key measures implemented by these countries to achieve the goals of sustainable development are analyzed, in particular in the field of energy, transport and agriculture. The main challenges and successes are identified, as well as lessons that Ukraine can adopt to effectively integrate the Green Course into its own policy.
The main measures of state policy aimed at increasing environmental awareness and compliance with environmental standards in the context of European cooperation for the development of a green economy are studied. Key instruments and political initiatives for greening the economy are identified. An analysis of the main global trends and stages of international cooperation within the framework of the green transition in the EU countries was carried out. The peculiarities of the formation of environmental awareness and an active civil society in which each participant adheres to the principles and standards of ecology are evaluated. The main documents regulating the activities of various subjects in various sectors of the economy are defined. On the example of Poland and Romania, it is confirmed that European countries implement a purposeful policy of sustainable development, focusing on cooperation between all participants of economic activity to comply with the principles of greening and socialization.
THEORETICAL AND CONCEPTUAL BASIS OF ECOLOGICAL BUSINESS DEVELOPMENT
Authors: Morozova Svitlana , Troyan Valentin
Published: September 2024

The state of development of ecological business in Ukraine today is characterized by a gradual increase in interest in sustainable development and the introduction of green technologies. The main obstacles remain imperfect legislation, lack of state support and funding, lack of proper infrastructure and insufficient level of environmental awareness among the population. In this context, there is also a need to develop theoretical and conceptual foundations that will help to clearly define approaches, principles and models of ecological business development. The purpose of the article is to determine the theoretical and conceptual foundations of the development of ecological business. The current state of development of ecological business in Ukraine is analyzed. It is noted that the development of ecological business is of key importance for the post-war reconstruction of Ukraine, as it contributes to the creation of a sustainable and environmentally responsible economy. It has been established that the development of ecological business can help Ukraine adapt to new international standards and requirements for sustainable development, which will contribute to the country's integration into global economic processes. The necessity and importance of researching the theoretical foundations of ecological business development in the context of the domestic economy has been proven. The components of the theoretical and conceptual foundations of the formation and development of ecological business are defined and revealed. The prospects for the development of ecological business in Ukraine are analyzed. Thus, ecological business is based on several key theoretical foundations, including the concept of sustainable development, the theory of natural capital, and the circular economy model. The conceptual foundations of the development of ecological business include the principles of ecological management, innovativeness and ecological technologies, as well as social responsibility of business. It is noted that for the further development of ecological business in Ukraine, a clear strategy is needed, which will include stimulating investments, improving legislation, developing infrastructure and increasing environmental awareness of society.
THEORETICAL BASIS OF THE FORMATION AND DEVELOPMENT OF GREEN BUILDING
Authors: Orlovska Yuliia , Kukhtyn Olexandr
Published: September 2024

Green construction is a key element of Ukraine's sustainable development, as it contributes to reducing the impact on the environment and increasing the energy efficiency of buildings, which is critically important in the face of global climate change and modern challenges. Green construction also supports Ukraine's integration into the international economy through the implementation of environmental standards, which increases the competitiveness of domestic companies. The purpose of the article is to single out the theoretical basis of the formation and development of green construction, as well as to determine the main problems in this field in Ukraine and ways to solve them. The analysis of Ukrainian and foreign studies have showed that the development of green construction in Ukraine has significant potential, especially under the condition of effective implementation of international standards and their adaptation to local realities, which will contribute not only to the preservation of the environment, but also to economic development, improving the quality of life and health population. The theoretical basis of the formation and development of green construction is systematized. The legislative and regulatory framework for green construction aimed at supporting ecologically sustainable development and construction in Ukraine has been analyzed. The main problems faced by green construction on the way to its development in Ukraine (insufficient regulatory framework, high cost of implementing ecological technologies, low level of public awareness and environmental culture, lack of qualified specialists, technical limitations and infrastructure challenges) are identified, and also given possible solutions to these problems. It is noted that for the further development of green construction, it is necessary to implement comprehensive strategies, which include stimulating investments in the green sector, developing and implementing new technologies, raising quality standards, and promoting environmental education. It is emphasized that government support through financial instruments, such as tax incentives and subsidies, can also contribute to increasing the number of green buildings.