bluuebunny/crossref_metadata_2025 huggingface dataset:
Spatial Distribution of Meningiomas: A Magnetic Resonance Image Atlas
Authors: Patel Ruchit V. , Yao Shun , Aguilar Murillo Efrain , Huang Raymond Y. , Bi Wenya Linda
Published: August 2024

BACKGROUND AND OBJECTIVES:

The size and anatomic location of meningiomas have been shown to correlate with distinct clinical manifestations, histopathological subtypes, and surgical risk. However, meningioma anatomic origin sites can be obscured in large tumors and those crossing compartments. We therefore sought to apply unbiased lesion mapping to localize intracranial meningioma distributions and their association with biology and grade.

METHODS:

MRI scans, World Health Organization (WHO) grade, and a molecularly Integrated Grade (IG) derived from cytogenetics were analyzed from adult patients with intracranial meningiomas. Semi-automated tumor segmentation was performed on T1-weighted contrast-enhanced MRI. We used the voxel-based lesion mapping technique to generate a meningioma atlas, mapping spatial frequency and correlating with tumor grades.

RESULTS:

Of 881 patients with meningioma (median age: 57 years, 68.8% female), 589 were WHO grade 1 (66.8%), 265 WHO grade 2 (30.1%), and 27 WHO grade 3 (3.1%) with a median tumor volume of 14.6 cm3. After molecular reclassification, 585 were IG-1 (66.4%), 160 IG-2 (18.2%), and 136 IG-3 (15.4%). Benign tumors were concentrated in and around the midline anterior skull base while malignant meningiomas were enriched in the falcine/parasagittal region and the sphenoid wing, similar to the distribution when stratified by chromosome 1p loss. Meningiomas exhibited sharper spatial clustering when stratified by the molecular IG than by WHO grade. WHO grade 2 meningiomas divided equally across IG 1-3, with corresponding partition of spatial distribution in the midline anterior skull base (in WHO grade 2, IG-1) and falcine/parasagittal and sphenoid regions (WHO grade 2, IG-3). Meningioma volumes significantly varied across age, sex, and WHO/IG grades.

CONCLUSION:

We demonstrate the utility of voxel-based lesion mapping for intracranial tumors, characterizing distinct meningioma distribution patterns across histopathological and molecularly defined grades. Molecular grading associated with sharper tumor spatial clusters, supporting a phenotype-genotype association in meningiomas.
Study of microbiological and physicochemical characteristics of fermented table olives in Cyprus and the multifunctional properties of the predominant microbiota
Authors: Αναγνωστόπουλος Δημήτριος
Published: August 2024

Η επιτραπέζια ελιά είναι ένα από τα πιο δημοφιλή, παραδοσιακά, ζυμούμενα προϊόντα και η παγκόσμια παραγωγή και κατανάλωσή της αυξάνονται εκθετικά. Σύμφωνα με τη μέθοδο του φυσικού τύπου παραγωγής, οι ελιές υπόκεινται σε απευθείας ζύμωση σε άλμη, χωρίς καμία προ-επεξεργασία ξεπικρίσματος. Η διαδικασία αυτή παραμένει μέχρι και σήμερα εμπειρική και ασταθής, καθώς επηρεάζεται έντονα από τις φυσικοχημικές ιδιότητες του καρπού και τη μεταβολική δραστηριότητα μικροοργανισμών, οι οποίοι είναι προσαρτημένοι στον καρπό ή μεταδίδονται από το περιβάλλον. Στις μέρες μας, ο εκσυγχρονισμός της διαδικασίας παραγωγής έχει κεντρίσει το ενδιαφέρον τόσο της βιομηχανίας όσο και της επιστημονικής κοινότητας, με στόχο τη σταθεροποίηση της ζύμωσης και συνεπώς, την αύξηση της προστιθέμενης αξίας του τελικού προϊόντος. Επιπλέον, η μείωση του επιπέδου χλωριούχου νατρίου που χρησιμοποιείται κατά τη διάρκεια της ζύμωσης, είναι μία από τις κυριότερες προκλήσεις της βιομηχανίας και απαιτήσεις της αγοράς. Για τον λόγο αυτό, στην παρούσα διατριβή, εφαρμόστηκε και μελετήθηκε η χρήση μιας εμπορικής καλλιέργειας εκκίνησης (L. plantarum) στη ζύμωση τόσο της κυπριακής όσο και της ποικιλίας Picual, ακόμη και σε χαμηλότερη συγκέντρωση NaCl (7%). Από τα αποτελέσματα προκύπτει η σημαντική συμβολή της καλλιέργειας εκκίνησης και προτείνεται η μόνιμη εφαρμογή της σε βιομηχανική κλίμακα. Επιπλέον, λαμβάνοντας υπόψη τόσο το βιομηχανικό ενδιαφέρον όσο και την απαίτηση των καταναλωτών για την ανάπτυξη νέων λειτουργικών τροφίμων, εξετάστηκε το τεχνολογικό και προβιοτικό προφίλ αυτόχθονων οξυγαλακτικών βακτηρίων και ζυμών, που απομονώθηκαν κατά τη ζύμωση της κυπριακής ελιάς. Τα αποτελέσματα έδειξαν ότι οι κυπριακές ελιές θα μπορούσαν να θεωρηθούν ως μία νέα πηγή προβιοτικών μικροοργανισμών, καθώς μια σειρά από απομονώσεις έδειξε ενδιαφέροντα βιοτεχνολογικά χαρακτηριστικά. Συνεπώς, συνίσταται η χρήση τους ως καλλιέργειες εκκίνησης σε μελλοντικές ζυμώσεις βιομηχανικής κλίμακας, με σκοπό την παραγωγή σταθερών, καινοτόμων και πιθανώς λειτουργικών επιτραπέζιων ελιών. Τέλος, η παρούσα διατριβή υποστηρίζει πλήρως την έννοια του τοπικού μικροβιακού terroir και μπορεί δυνητικά να αποτυπώσει το προϊόντα.
Poweromin X Ten, a polyherbal formulation improves male sexual function: In vivo and network pharmacology study
Authors: Bojja Sree Lalitha , Kolathur Kiran Kumar , Chaudhari Bhim Bahadur , Hari Gangadhar , Byregowda Bharath Harohalli , Meka Sai Teja , Selvan Esekia Raja , Moorkoth Sudheer , Kumar Nitesh , Austin Anoop , Rao C. Mallikarjuna
Published: August 2024

Introduction Poweromin X Ten (PXT) is a polyherbal formulation, traditionally used to enhance male sexual function. However, the safety and benefits of PXT have not been scientifically evaluated. Therefore, the present study investigated the toxicity and aphrodisiac potential of PXT in male rats and explored its principal mechanisms of action. Methods Male Wistar rats were orally administered PXT (50 or 100 mg/kg) for 28 days, and sexual activity parameters, including latency and frequency of mounting and intromissions, were studied. The reproductive toxicity and spermatogenic potential were also examined. Furthermore, dopamine and serotonin levels in brain regions associated with sexual activity were assessed. Network analysis was used to identify the key bioactive compounds and their core targets involved in their beneficial actions. Results Treatment with PXT improved sexual activity in male rats, as evidenced by reduced mounting and intromission latency and a significant increase in mount frequency. Moreover, PXT exhibited spermatogenic potential and did not induce reproductive toxicity. Notably, treatment with 50 mg/kg PXT elevated dopamine levels in median preoptic area and hypothalamus. Pathway analysis indicated that PXT primarily modulated the PI3K-Akt, calcium, and MAPK signalling pathways to enhance male sexual function. Network analysis identified macelignan, β-estradiol, testosterone, and paniculatine as key bioactive components of PXT, which likely act through core targets, such as androgen receptor (AR), Mitogen-activated protein kinase 3 (MAPK3), epidermal growth factor receptor (EGFR), estrogen receptor 1 (ESR1), and vascular endothelial growth factor (VEGF) to facilitate the improvement of male sexual function. Conclusion Study results suggest that PXT is a safer alternative with aphrodisiac and spermatogenic potential. These effects are partly attributed to the enhanced dopamine levels in the brain. Furthermore, this study provides insights into the specific signalling pathways and bioactive compounds that underlie the improvements in male sexual function associated with PXT.
Evaluation of centralised and decentralised models of care during the 2020 Ebola Virus Disease outbreak in Equateur Province, Democratic Republic of the Congo: A brief report
Authors: Lampaert Emmanuel , Nsio Mbeta Justus , Nair Divya , Mashako Maria , De Weggheleire Anja , Sprecher Armand , M. Coulborn Rebecca , Ahuka-Mundeke Steve
Published: August 2024

Background Traditionally in the Democratic Republic of the Congo (DRC), centralised Ebola treatment centres (ETCs) have been set exclusively for Ebola virus disease (EVD) case management during outbreaks. During the 2020 EVD outbreak in DRC’s Equateur Province, existing health centres were equipped as decentralised treatment centres (DTC) to improve access for patients with suspected EVD. Between ETCs and DTCs, we compared the time from symptom onset to admission and diagnosis among patients with suspected EVD. Methods This was a cohort study based on analysis of a line-list containing demographic and clinical information of patients with suspected EVD admitted to any EVD health facility during the outbreak. Results Of 2359 patients with suspected EVD, 363 (15%) were first admitted to a DTC. Of 1996 EVD-suspected patients initially admitted to an ETC, 72 (4%) were confirmed as EVD-positive. Of 363 EVD-suspected patients initially admitted to a DTC, 6 (2%) were confirmed and managed as EVD-positive in the DTC. Among all EVD-suspected patients, the median (interquartile range) duration between symptom onset and admission was 2 (1-4) days in a DTC compared to 4 (2-7) days in an ETC (p<0.001). Similarly, time from symptom onset to admission was significantly shorter among EVD-suspected patients ultimately diagnosed as EVD-negative. Conclusions Since <5% of the EVD-suspected patients admitted were eventually diagnosed with EVD, there is a need for better screening to optimise resource utilization and outbreak control. Only one in seven EVD-suspected patients were admitted to a DTC first, as the DTCs were piloted in a limited and phased manner. However, there is a case to be made for considering decentralized care especially in remote and hard-to-reach areas in places like the DRC to facilitate early access to care, contain viral shedding by patients with EVD and ensure no disrupted provision of non-EVD services.
Paleo-species distribution modelling in the marine realm: protocol for a global scoping review
Authors: Ben Lamine Emna , Agiadi Konstantina , Bas López Maria , Beaugrand Grégory , Theodoropoulou Tatiana , Raybaud Virginie
Published: August 2024

Background Studying the spatial distribution of marine species and its alterations through time is fundamental for understanding how they respond to environmental changes, as well as the changes of marine biodiversity, its geographic patterns, and how to best preserve it. Species distribution models (SDM) and Ecological Niche Models (ENM) are statistical tools widely used to investigate distribution range shifts under future and past climate change. The present work provides a protocol for conducting a scoping review (ScR) to assess the contribution of SDM and ENM to the study of past environmental suitability, its spatial and temporal extent and gaps, as well as to identify methodological challenges. Protocol The ScR follows the Joanna Briggs Institute (JBI) methodology. Two online databases, Web of Science and Scopus, will be used for the bibliographic search. Inclusion criteria will be as follows: studies applying SDM and/or ENM in the marine realms worldwide, with clear methodological details, to identify to what extent they contributed to paleobiology. Both peer-reviewed articles, book chapters and grey literature will be considered for eligibility. No search limitations will be applied regarding publication year, geographic area and source type. Studies in English, Spanish and French will be reviewed. The Covidence software will be used for document selection and data extraction. Conclusions This comprehensive approach will provide a visual representation of the available studies, enhancing the understanding and interpretation of the results focusing on the contribution of SDM and ENM to species potential ancient distribution knowledge, identifying the spatial and temporal extent and the presence of gaps of knowledge in their use.
Bad Deals and Tragic Pacts: The impact of the EU’s management of migration through the externalisation of its borders on ‘Women on the Move’
Authors: Vella Mary Grace
Published: August 2024

In recent years the EU has become increasingly restrictive in its regulation of irregular migration flows despite its outward sustained discourse of safeguarding human lives and the protection of fundamental rights and freedoms. As part of this restrictive strategy, the EU has invested heavily in the securitisation and the management of migration through the externalisation of its borders. The EU-Turkey Deal struck in 2016 paved the way for further agreements with third countries with poor gender equality and human rights records, such as Libya and Tunisia. This externalisation of migration constitutes an important feature of the New Pact on Migration and Asylum adopted in 2023 with the aim of establishing a common asylum process at EU level. Asylum seekers, particularly girls and women are placed at added risk from these restrictive policies and policies of externalisation, as apart from dangers faced by all asylum seekers, they are at increased risk of human trafficking, sexual abuse and exploitation, and others forms of gender-based violence. Despite offering a short-sighted measure to a complex problem and the adverse humanitarian repercussions and gross human rights violations, particularly on female refugees and asylum seekers, such deals and pacts constitute an integral aspect of the EU’s strategic agenda of managing migration through the externalisation of its borders. The article proposes a number of alternative solution-oriented measures which safeguard fundamental human rights and freedoms, in particular the right to asylum for refugee women and girls.
How dairy food affects prostate cancer - a literature overview
Authors: Bentkowska Zuzanna , Bogoń Aleksandra , Urbańska Karolina , Serkis Barbara , Miazga Małgorzata , Celichowska Magdalena , Golemo Jagna , Dębińska Julia , Ostojska Magdalena , Górska Magdalena
Published: August 2024

Introduction: Prostate cancer is one of the most common type of tumors. Potential factors influencing this neoplasm are subject of many scientific studies as a scarce number of risk variables have been well-established so far.
Purpose of the work: The objective of this review is to collect and interpret recent findings regarding dairy food and its influence on prostate cancer.
Materials and method: A systematic research was conducted using the PubMed database. Articles in English published from 2015 to 2024 were selected using keywords: dairy products, dairy, milk, prostate cancer.
State of knowledge: There is an overall positive association between total dairy products, milk and prostate cancer risk. Although whole milk is not considered as a risk factor, it has been reported that high-fat milk has a positive association with fatality rate and recurrence. Several studies presented a new potential pathomechanisms of dairy’s influence on prostate tumors. Casein, IGF-1 and exosomes are labeled as mediators between high dairy food intake and prostate cancer occurrence.
Summary: As of now, there is not strong enough evidence to limit dairy food intake in the whole population. Further research is needed to explore the relationship between dairy consumption and prostate cancer. Men with diagnosed prostate tumors are suggested to eat food according to the Mediterranean diet as it has been reported that it decreases cancer-specific and overall mortality.
The Substitution of Purslane Weed (Portulaca oleracea L.) Flour and Glucomannan Powder on Organoleptic and Proximate Test of Instant Noodles
Authors: Wati Dini Prastyo , Fajrina Meinira Dinar , Putra Sahasika Sean , Suryani Titik
Published: August 2024

Instant noodles are a food product that the public highly favors because of their diverse taste, easy presentation, and economical price. Instant noodles cannot be considered whole food because they do not meet the needs of balanced nutrition for the body. Purslane flour (Portulaca oleracea L.) contains macronutrients and micronutrients in the form of carbohydrates, protein, dopamine, potassium salts, tannins, saponins, vitamin A (β-carotene), Vitamin B, Vitamin C, nicotinic acid and natural antioxidants related to fatty acids omega 3 by 44.29%. This study contributed to compare the effectiveness of the substitution of Purslane flour and glucomannan powder on organoleptic test instant noodles. This study was an experiment with a completely randomized design of two-factorial with six treatments including the formulation of purslane flour 25%, 30%, and 35%, while glucomannan formulation of 5%, 10%, 15% with two temperature treatments, 50 °C, and 60 °C. We conducted an organoleptic test with statistical analysis t-test and descriptive. The substitution of purslane flour and glucomannan in instant noodles gave the best organoleptic characteristics in the K2S2 treatment (the formulation of 60% wheat flour, 30% purslane flour, and 10% glucomannan at a drying temperature of 60 °C) with proximate analysis content of 12.26% moisture, 5.53% ash, 5.13% fat, 13.91% protein, and 63.14% carbohydrates.
The Effect of Soaking Time and Size of Fruit Pieces on Pineapple Infused Tea Characteristic
Authors: Andeswari Arvi Yashinta , Zahro Nabila Hidayatuz , Widyasaputra Reza , Bimantio Mohammad Prasanto , Ruswanto Adi
Published: August 2024

Fruit-infused tea become one of the exciting innovations in recent years. Fruit addition could improve the freshness and richness of tea drinks. Pineapple has good potency when used in the making of fruit-infused tea. The soaking time and size of fruit pieces were essential to determine because there is a solid-liquid extraction process in making pineapple-infused tea. This research aimed to assess the effect of soaking time and the size of fruit pieces on the characteristics of pineapple-infused tea. This research used Complete Block Design (CBD) with two factors: (A) soaking time and (B) size of fruit pieces. Factor A consisted of 3 levels: A1 = 3 hours; A2 = 6 hours; A3 = 9 hours. Factor B consisted of 3 levels: B1 = 0.5×0.5×0.5 cm; B2 = 1×1×1 cm; B3 = 1.5×1.5×1.5 cm. The treatment was replicated two times. The analysis was antioxidant activity, vitamin C, pH, total flavonoid, and tannin content. The result showed a significant difference in soaking time on tannin content, vitamin C, pH parameters, and the size of fruit pieces on pH parameters. The best result was obtained in 1×1×1 cm of fruit pieces and 3 hours soaking time with 13.20 ± 0.01% vitamin C, 17.28 ± 0.83% tannin content, 0.107 ± 0.018 % flavonoid content, 92.56 ± 1.99 % antioxidant activity and 4.95 ± 0.03 pH value. This research provides data about the difference between soaking time and the size of fruit pieces to the pineapple-infused tea characteristic.
Analisis Faktor yang Mempengaruhi Tingkat Kecelakaan Lalu Lintas di Kabupaten Sikka
Authors: Putri Agnesia Sonia Yulian , Aswim Danar , Natsir Rodja Abdul
Published: August 2024

Penelitian ini analisis faktor yang mempengaruhi tingkat kecelakaan lalu lintas di Kabupaten Sikka. Penelitian ini bertujuan untuk mengetahui apa faktor yang mempengaruhi tingkat kecelakaan lalu lintas di Kabupaten Sikka dan bagaimana upaya penegakkan hukum yang dilakukan Polres Sikka. Metode penelitian yang digunakan adalah metode deskriptif  Kuantitatif. Jenis data Yang digunakan adalah data primer dan data sekunder. Data primer diperoleh dari Observasi, wawancara sedangkan data sekunder diperoleh dari studi dokumen. Teknik analisis Data yaitu dengan cara pengumpulan data dianalisis berdasarkan rumusan masalah yang hendak diketahui faktor penyebab dan solusi yang dapat dipergunakan. Berdasarkan hasil analisis, faktor penyebab yang memicu terjadinya kecelakaan Lalu lintas adalah faktor manusia,  faktor kendaraan dan faktor jalan. Faktor penyebab Yang paling dominan adalah manusia.selain faktor manusia dan Faktor kendaraan, faktor jalan juga menjadi pemicu terjadinya kecelakaan lalu lintas  Karena dari hasil observasi yang dilakukan terdapat jalan  yang kurang penerangan jalan, jalan berlubang dan jalan berkelok.
Kajian Etnomatematika pada Tenun Ikat Utan Dala Mawarani Khas Kabupaten Sikka
Authors: Dhema Magdalena , Fitri Mohammad , Anomeisa Agnesia Bergita
Published: August 2024

Penelitian ini bertujuan untuk mengkaji etnomatematika pada tenun ikat Utan Dala Mawarani yang merupakan salah satu warisan budaya khas Kabupaten Sikka, serta mengeksplorasi bagaimana konsep-konsep matematis yang terdapat dalam tenun ikat ini dapat diterapkan dalam pembelajaran matematika. Pendekatan kualitatif dengan metode etnografi digunakan untuk memahami pola, motif, dan teknik tenun yang melibatkan konsep-konsep matematis seperti simetri, geometri, dan aritmetika. Data dikumpulkan melalui observasi langsung, wawancara mendalam dengan pengrajin tenun, serta dokumentasi proses pembuatan tenun ikat. Hasil penelitian menunjukkan bahwa tenun ikat Utan Dala Mawarani mengandung berbagai elemen matematis. Misalnya, motif tenun yang menggunakan pola simetris menunjukkan pemahaman intuitif tentang konsep refleksi dan rotasi. Selain itu, teknik pengaturan benang dalam tenun mencerminkan pemahaman tentang pola deret aritmetika dan geometri. Pemahaman ini dapat dijadikan sebagai media kontekstual dalam pembelajaran matematika di sekolah, khususnya untuk materi geometri dan pola bilangan. Penelitian ini juga menemukan bahwa pengintegrasian etnomatematika ke dalam kurikulum pembelajaran matematika dapat meningkatkan motivasi dan pemahaman peserta didik. Dengan menggunakan tenun ikat sebagai media pembelajaran, siswa dapat melihat langsung aplikasi nyata dari konsep-konsep matematis, yang pada gilirannya dapat meningkatkan minat dan apresiasi peserta didik terhadap matematika dan budaya lokal. Secara keseluruhan, penelitian ini memberikan kontribusi penting dalam bidang etnomatematika dan pendidikan matematika dengan menunjukkan bahwa warisan budaya lokal seperti tenun ikat tidak hanya memiliki nilai estetika dan historis, tetapi juga nilai edukatif yang dapat dimanfaatkan dalam pembelajaran. Rekomendasi untuk penelitian lebih lanjut mencakup pengembangan modul pembelajaran berbasis etnomatematika dan uji coba implementasinya di kelas.
Dampak Media Sosial terhadap Pelanggaran Nilai-Nilai Karakter Siswa di MTs Muhammadiyah Wuring
Authors: Ahmadi Ahmadi , Natsir Rodja Abdul , Wahab Muhammad Ikhsan
Published: August 2024

Penelitian ini bertujuan untuk untuk mengetahui apa saja dampak dari media sosial terhadap pelanggaran nilai-nilai karakter siswa dan untuk mengetahui bagaimana upaya mengatasi siswa yang melanggar nilai-nilai karakter. penelitian ini menggunakan metode kualitatif. Penelitian ini menggunakan dua sumber data yaitu data primer: kepala sekolah, guru dan siswa, data sekunder: data yang diperoleh dari jurnal dan artikel. Berdasarkan dari hasil penelitian terhadap dampak media sosial terhadap pelanggaran nilai-nilai karakter siswa di MTS Muhammadiyah Wuring maka dapat disimpulkan bahwa dampak media sosial  terhadap pelanggaran nilai-nilai karakter siswa, lebih banyak terlihat dampak negatif seperti siswa kurang dalam belajar, lebih banyak memainkan HP daripada membuka buku. Apalagi saat ini sistem dimana rata-rata siswa memang memiliki HP. Siswa juga kurang peduli terhadap lingkungan, tidak melihat kondisi lingkungan terkadang terbiasa berkumpul membahas hal-hal viral yang ada di media sosial. Bahkan berkumpul untuk membuat video bersama dan berjoget bersama. Siswa sekolah masih sangat rentan terpengaruh oleh lingkungan, belum lagi saat untuk siswa sebelum mampu membedakan yang mana yang baik dan yang buruk, sedangkan di dalam media sosial tentunya memiliki dampak positif dan negatif. Para siswa sekarang lebih banyak menggunakan handphone dan banyak membicarakan hal-hal yang disebut viral di media sosial daripada membahas tentang pembelajaran. Siswa yang menggunakan media sosial sejak lama dengan tujuan hanya untuk mengisi waktu luang, bahkan buat hiburan bagi mereka apabila bosan setelah belajar. Bahkan media tidak pernah dijadikan sebagai media belajar, meskipun ada konten edukasi, mereka hanya melewatkannya saja, tidak mengikuti. Hal ini tentunya menjadi hal yang sangat mengkhawatirkan bagi masa depan anak, selain digunakan sebagai sarana hiburan tetapi banyak sekali unggahan-unggahan yang merusak nilai-nilai karakter dan perilaku anak. Hal ini tentunya diperlukan pengawasan bagi orang tua terhadap anaknya dalam penggunaan media sosial, agar karakter dalam diri anak terjaga bermoral, beretika serta berakhlak mulia.
Dampak Bisnis Fashion Online terhadap Tingkat Pendapatan Pedagang Fashion di Kampung Wuring, Kabupaten Sikka
Authors: Neni Neni , Kholiq Abdul , Rahman Nurdin
Published: August 2024

Penelitian ini bermaksud untuk menjelaskan pengaruh pebisnis fashion online terhadap tingkat pendapatan pedagang fashion offline di kampung wuring. Penelitian ini menggunakan pendekatan kualitatif. Sumber data dari penelitian ini berasal dari hasil buku, jurnal, literatur lainnya terkait dampak bisnis fashion online terhadap tingkat pendapatan pedagang fashion offline. perkembangan teknologi informasi telah membawa perubahan yang sangat besar dibidang penjualan fashion.dengan berkembangnya zaman yang semakin modern, teknologi berkembang begitu pesat. Pasar online mulai hadir di tengah-tengah masyarakat sebagai alternatif belanja. kelebihan dan kekurangan yang dimiliki oleh online shop dan pedagang offline dapat mempengaruhi minat beli konsumen. Konsumen yang cenderung tidak ingin repot lebih memilih belanja di penjual fashion online, sedangkan konsumen yang terlalu takut dengan resiko belanja secara online lebih memilih berbelanja di pedagang fashion offline atau ke toko. Berdasarkan hasil wawancara dengan beberapa pedagang fashion di kampung wuring dapat disimpulkan bahwa para pedagang offline di kampung wuring memandang bahwa jual beli online memang semakin diminati oleh berbagai kalangan masyarakat dengan kenyamanan dan kemudahan yang ditawarkannya. Perihal tersebut juga berdampak pada usaha jualan mereka. Dampak yang dirasakan para pedagang akibat adanya belanja online yaitu pada penurunan jumlah pembeli dan pendapatan mereka per harinya dan para pedagang merasa kalah saing dengan pedagang online dari segi harga dan akses yang mudah.
Penggunaan Alat Peraga Keranjang Angka untuk Meningkatkan Hasil Belajar Peserta Didik Kelas II SDI Waioti
Authors: Sanyati Ine , Wahyuningsih Wahyuningsih , Wahyuningsih Wahyuningsih , Rahmawati Tanti Diyah , Rahmawati Tanti Diyah
Published: August 2024

Matematika merupakan pelajaran yang sangat penting. Matematika adalah bidang penelitian yang abstrak, dan objek pembelajaran matematika adalah benda-benda yang abstrak. Oleh sebab itu peserta didik perlu membayangkan konsep tersebut. Hal ini menunjukkan bahwa objek matematika sulit untuk diamati dan dipahami melalui panca indera. Sebagian peserta didik yang masih menganggap pelajaran matematika sebagai pelajaran yang sulit, khususnya pada tingkat sekolah dasar karena pada tingkat ini taraf berpikir mereka masih pada tahap operasional konkret, dimana kemampuan yang ditunjukkan pada tahap ini adalah kemampuan proses berpikir untuk mengoperasikan kaidah-kaidah logika yang masih tetap terbatas pada objek yang nyata. Dengan demikian untuk mempelajari matematika yang bersifat abstrak, media yang digunakan agar peserta didik dapat memahami objek tersebut adalah media alat peraga. Alat peraga tersebut digunakan dalam pembelajaran matematika untuk mengurangi keabstrakan materi matematika saat mempelajari objek matematika. Tujuan dalam penelitian ini yaitu untuk mengetahui bagaimana Penggunaan  alat peraga keranjang angka dalam menentukan nilai tempat untuk meningkatkan hasil belajar peserta didik. Penelitian ini dilakukan di SDI Waioti. Metode penelitian yang digunakan adalah penelitian Tindakan kelas. Hasil penelitian ini menunjukkan bahwa penggunaan alat peraga keranjang angka dalam menentukan nilai tempat dapat meningkatkan hasil belajar peserta didik dengan rata-rata siklus 1 sebesar 64,71 menjadi 90,59 disiklus ke II.
Pengembangan Alat Peraga Puzzle Pecahan Sebagai Media Pembelajaran Matematika pada Materi Pecahan Sederhana Kelas III SDI Waioti
Authors: Umar Safitrin , Anomeisa Agnesia Bergita , Wahyuningsih Wahyuningsih
Published: August 2024

Tujuan penelitian ini untuk mengembangkan alat peraga puzzle pecahan sebagai media pembelajaran matematika pada materi pecahan sederhana kelas III yang valid, praktis, dan efektif. Metode penelitian yang digunakan adalah penelitian dan pengembangan atau Research and Development (RD), dan model pengembangan yang digunakan yaitu model 4D yang terdiri dari empat tahapan yaitu tahap pendefinisian (define), tahap perancangan (design), tahap pengembangan (development), dan tahap penyebaran (disseminate). Subjek dalam penelitian ini adalah peserta didik kelas III SDI Waioti sebanyak 25 peserta didik, ahli, dan guru. Instrumen yang digunakan dalam penelitian ini adalah lembar validasi, angket, dan soal tes hasil belajar. Hasil penelitian menunjukkan pengembangan alat peraga puzzle pecahan sebagai media pembelajaran matematika pada materi pecahan sederhana menunjukkan bahwa: (1) hasil uji validitas alat peraga puzzle pecahan memperoleh persentase 95,56% dengan kriteria sangat valid; (2) hasil uji kepraktisan angket respon guru memperoleh persentase 97,50% dengan kriteria sangat praktis; (3) hasil uji kepraktisan angket respon peserta didik memperoleh persentase 99% dengan kriteria sangat praktis; (4) hasil uji keefektifan memperoleh persentase 100% dengan kriteria sangat efektif. Oleh karena itu, dapat disimpulkan bahwa alat peraga puzzle pecahan telah memenuhi kriteria sangat layak digunakan sebagai media pembelajaran matematika, terutama dalam pembelajaran materi pecahan sederhana.
Mensuração do grau de inovação de empresas participantes do Projeto ALI-rural no município de João Lisboa, Maranhão, Brasil
Authors: Batista Aldineide de Jesus Padilha , Silva Aline Maracaipe da , Ferreira Marcia Maria Martins , Viana Diego Carvalho
Published: August 2024

Na Microrregião de Imperatriz no estado do Maranhão, onde está localizado o município de João Lisboa, a agricultura familiar tem um papel importante na produção de diversos produtos. Na agricultura do município de João Lisboa, destacam-se a produção de culturas como a mandioca, o milho, o arroz, o feijão, a banana. O programa envolveu a participação de 13 empresários rurais que atuam em diversas atividades agrícolas. O objetivo foi mensurar o grau de inovação de empresas participantes do Projeto ALI rural no município de João Lisboa no estado do Maranhão, através de diagnóstico e soluções implementadas.A Jornada ALI compreendeu oito encontros individuais e dois encontros coletivos, adotando uma abordagem sistêmica que empregou um plano de ação e ferramentas voltadas para alcançar resultados concretos para os empresários rurais. Este trabalho apresenta os resultados do grau de inovação e do impacto das soluções implementadas. Houve um impacto expressivo das inovações no faturamento de 9 das 13 empresas participantes, as quais registraram um aumento superior a 50%. Ao término da Jornada ALI rural, fica clara uma transformação essencial, especialmente na mentalidade dos proprietários rurais, que passaram a encarar suas propriedades de forma mais estratégica e orientada para a inovação.
Innovation and management of fish farming enterprises in the western mesoregion of Maranhão, Brazil
Authors: Ferreira Klayton Antonio Lins , Jacinto John Jacinto Santos , Ferreira Victor Rodrigues , Viana Diego Carvalho
Published: August 2024

In Brazil, fish farming has been growing in recent years, with a highlight in production and innovation in the sector. The objective was to evaluate the innovation and management of rural enterprises in the fish farming sector in the municipalities of Buriticupu and Bom Jesus das Selvas, in order to generate information that can serve as a basis for implementing actions, both in the public and private sectors, for the development of the activity and generation of income and employment. The study was conducted over a period of eight months (September 2022 to March 2023), with six fish farmers from the municipalities of Buriticupu and Bom Jesus das Selvas, located in the western region of the state of Maranhão. Ten face-to-face meetings were held, eight individual and two collective. In terms of management control, it was observed that in the initial evaluation, the enterprises scored 1.67, and in the final evaluation, 2.33. In the final management control assessment, a score of 2.33 was obtained, indicating a 39.5% increase rate after the actions taken. Regarding the improvement of the production process, it was observed that initially the score was 2.26, which implies that the producers did not prioritize the effectiveness of the processes and activities to be developed, leading to inefficiency in working time and waste of raw materials. The fish farming enterprises showed improvements in management control and production processes. The actions and tools used in this study showed good applicability on the properties, promoting such improvements and advancements, albeit small ones.
Cultura da inovação de produtores rurais da microrregião de Chapadinha, Maranhão, Brasil
Authors: Damasceno Paulo Junio Silva , Borges Rosa Amélia Dias , Costa Deniz Sousa , Macedo Elison Silva de
Published: August 2024

A capacidade de inovar está associada à agregação de conhecimento externo ou interno. O objetivo com este trabalho foi avaliar o impacto da aplicação de ferramentas de inovação do projeto Ali rural sobre o desenvolvimento da cultura e do ambiente organizacional da inovação em pequenos negócios rurais da microrregião de Chapadinha. Participaram do Programa Ali rural 11 produtores, distribuídos entre os municípios de Anapurus e Chapadinha. Após o 10° e último encontro os produtores responderam a um questionário semiestruturado para verificar elementos da cultura organizacional da inovação e informações que permitissem melhor compreensão sobre o contexto das empresas. A atividade produtiva com maior prevalência foi a horticultura, seguida da piscicultura e da fruticultura. A jornada Ali rural contribui positivamente para o desenvolvimento da cultura da inovação em pequenas empresas rurais nos municípios de Anapurus e Chapadinha, Maranhão, Brasil. A participação de produtores rurais no programa aumenta a sua confiança para prosseguir com o desenvolvimento de inovações em suas propriedades. Em um ambiente repleto de gargalos socioeconômicos para a aplicação de inovações, as ferramentas de inovação do projeto Ali rural melhoram o status da inovação com relação a controles gerencias, melhoria do processo produtivo, marketing e vendas, redução de custos e novos produtos em pequenos negócios rurais. O projeto ALI rural do Sebrae contribui positivamente para o desenvolvimento da cultura da inovação em pequenos negócios rurais. A participação de empresários rurais no projeto aumenta a sua confiança para prosseguir com o desenvolvimento de inovações em suas empresas.
Creating a safe space
Authors: Frisby Claire
Published: August 2024

Claire Frisby discusses the current calls for a DCP wellbeing community with dental therapist Victoria Wilson.
The effect of dental treatment using conscious sedation therapy on patient satisfaction
Authors: Kim Eun-Hye , Bae Sung-Suk , Lee Mi-Ra , Jun Soo-Kyung , Kang Min-Kyung
Published: August 2024

Objectives: This study aimed to investigate the effects of conscious sedation on patient satisfaction with dental treatment. Methods: The survey included questions on the patients’ general characteristics, dental treatment fear, anxiety, and satisfaction, and patient evaluation by an observer. Statistical analyses were performed using SPSS 20.0 ver. and data were analyzed using frequency analysis, independent t-test, Pearson’s correlation coefficient, and multilinear regression analysis. Results: Patients who received conscious sedation therapy showed significantly lower levels of dental fear and anxiety, whereas their dental treatment satisfaction was significantly higher than that of patients who received regular dental treatment (p<0.05). Dental treatment fear, anxiety, satisfaction, and conscious sedation depth were significantly correlated in patients who received conscious sedation therapy (p<0.05). Factors influencing dental treatment satisfaction included age, weight, use of medication, smoking habits, use of conscious sedation therapy, dental treatment fear and anxiety, and conscious sedation depth (p<0.05). Conclusions: Conscious sedation therapy can be an effective method to reduce dental treatment fear and anxiety and improve patient satisfaction.
Determining the Extent of damage in Snapped Southern Yellow Pine Trees with Acoustic Testing
Authors: Smidt Mathew F. , Musah Munkaila , Mitchell Dana , Cannon Jeffery B. , Via Brian K.
Published: August 2024

Salvage of downed timber following a windstorm allows recovery of management options for landowners and wood products for industry. Because wood volumes are large and logging, transportation, mill storage, and processing capacities are limited, avoiding the selection of logs with damage can conserve those resources. Visual damage indicators are typically used to select and differentiate products, but damaged logs are still delivered to mills. Following experimental tree winching in 2021 and a tornado in 2023, we assessed lengths of broken trees with a Fakopp microsecond timer. Using a recognized defect limit (10% deviation from the maximum acoustic velocity) about 80 percent of volume in broken tops could be recovered. Standard rules of thumb applied from the end of visible damage resulted in the recovery of about 50 percent of the volume with a relatively low defect rate (<10%). Applying bucking rules developed from acoustic measurements based on distance from snap might be easier to apply and increase recovery rates to over 70 percent of broken top volume.
"Immorality and Immortality"? Salvation and Scandal at Michigan's House of David
Authors: Sterne Evelyn
Published: August 2024

ABSTRACT: The House of David, a Christian Israelite commune founded in Benton Harbor, Michigan, in 1903, attracted believers who surrendered all assets and lived as celibate vegetarians in exchange for community, economic security, and the promise of immortality. The colony grew famous for its popular baseball teams, orchestras, and amusement park. It also became notorious after a series of lawsuits charged leader Benjamin Purnell (1861–1927) of being a fraud who had swindled believers out of their life savings and perpetrated "gross immoralities" upon young women. This article analyzes why the colony was dogged by controversy and asks what that reveals about why critics have sought to delegitimize new religious movements. It argues that the House of David attracted scrutiny not only because of its distinctive lifestyle and theology, but also because it did not fit prevailing definitions of what a religion should look like.
Photothermal optical coherence microscopy for studying lipid architecture in human carotid arteries
Authors: Doug Deen Aaron , López-Marín Antonio , Riksen Jonas J. M. , van der Steen Antonius F. W. , van Soest Gijs
Published: August 2024

Photothermal optical coherence microscopy (PT-OCM) combines the high-resolution, label-free morphological imaging of OCM with the ability to discriminate tissue composition through phase-sensitive photothermal imaging. In this study, we perform 2D imaging of human carotid endarterectomies to spectrally determine lipid distribution, with verification via histologically stained samples. The structural information from OCM is combined with the spectral information gained from measuring the resulting sample surface displacement from thermoelastic expansion, following light irradiation. PT-OCM is thus demonstrated as a potential tool in the investigation of atherosclerotic plaque lipids, contributing towards the understanding of plaque instability.
Achromatic solutions of the color constancy problem: the Helmholtz–Kohlrausch effect explained
Authors: van Trigt C.
Published: August 2024

For given tristimulus values X, Y, Z of the object with reflectance ρ(λ) viewed under an illuminant S(λ) with tristimulus values X0, Y0, Z0, an earlier algorithm constructs the smoothest metameric estimate ρ0(λ) under S(λ) of ρ(λ), independent of the amplitude of S(λ). It satisfies a physical property of ρ(λ), i.e., 0≤ρ0(λ)≤1, on the visual range. The second inequality secures the condition that for no λ the corresponding patch returns more radiation from S(λ) than is incident on it at λ, i.e., ρ0(λ) is a fundamental metameric estimate; ρ0(λ) and ρ(λ) differ by an estimation error causing perceptual variables assigned to ρ0(λ) and ρ(λ) under S(λ) to differ under the universal reference illuminant E(λ)=1 for all λ, tristimulus values X
E
, Y
E
, Z
E
. This color constancy error is suppressed but not nullified by three narrowest nonnegative achromatic response functions A
i
(λ) defined in this paper, replacing the cone sensitivities and invariant under any nonsingular transformation T of the color matching functions, a demand from theoretical physics. They coincide with three functions numerically constructed by Yule apart from an error corrected here. S(λ) unknown to the visual system as a function of λ is replaced by its nonnegative smoothest metameric estimate S0(λ) with tristimulus values made available in color rendering calculations, by specular reflection, or determined by any educated guess; ρ(λ) under S(λ) is replaced by its corresponding color R0(λ) under S0(λ) like ρ(λ) independent of the amplitude of S0(λ). The visual system attributes to R0(λ)E(λ) one achromatic variable, in the CIE case defined by y(λ)/Y
E
, replaced by the narrowest middle wave function A2(λ) normalized such that the integral of A2(λ)E(λ) over the visual range equals unity. It defines the achromatic variable ξ2, A(λ), and ξ as described in the paper. The associated definition of present luminance explains the Helmholtz–Kohlrausch effect in the last figure of the paper and rejects CIE 1924 luminance that fails to do so. It can be understood without the mathematical details.
Bridging evidence gaps in attributing loss and damage, and measures to minimize impacts
Authors: Engdaw Mastawesha Misganaw , Mayanja Brian , Rose Sabrina , Loboguerrero Ana Maria , Ghosh Aniruddha
Published: August 2024

Losses and damages from climate change have been increasing as global temperatures continue to rise above pre-industrial levels. Low-income, climate vulnerable countries bear a disproportionate share of these losses and damages. After decades of international negotiations, the Loss and Damage Fund was established in late 2022, aiming at addressing both economic and non-economic losses arising from slow- and sudden-onset climate change events. Recognizing the complex nature of climate-related events, the establishment of the Loss and Damage Fund underscores an urgent need for precise attribution of these events to climate change, highlighting the fund’s reliance on scientific evidence to guide its efforts. Attribution science, which decouples specific causes of changes in climate hazards and impacts, can support loss and damage negotiations. Low-income countries, which have contributed the least to climate change, are experiencing more severe impacts. However, data quality and coverage required for scientific studies to attribute loss and damage to climate change remain limited in these developing countries. In this paper, we highlight the challenges to attribute losses and damages to climate change in developing countries and underscore strategies to overcome those challenges using examples from the agrifood sector. These strategies have implications for the operationalizing of the Loss and Damage Fund. We emphasize how improving data availability and quality can lead to rigorous scientific conclusions, supporting evidence-based, inclusive, and effective interventions. We also indicated measures that enable strengthening climate resilience to avoid and minimize losses and damages.
Predictors of health-related quality of Life for COVID-19 survivors living in Dhaka, Bangladesh: A repeated Follow-Up after 18 months of their recovery
Authors: Rashid Md. Utba , Dalal Koustuv , Khan Md. Abdullah Saeed , Monisha Umme Kulsum , Sagar Soumik Kha , Mishu Tahmina Zerin , Nabi Mohammad Hayatun , Hawlader Mohammad Delwer Hossain
Published: August 2024

The study aimed to explore the key determinants that impact the quality of life (QoL) transformation of those who have recuperated from COVID-19 in the Dhaka metropolis, particularly 18 months post-recovery. RT-PCR confirmed that 1,587 COVID-19 patients from Dhaka were included in the study. The baseline was June ‐ November 2020, subsequently recovered and interviewed 18 months after their initial recovery. The follow-up included 1587 individuals using the WHOQOL-BREF questionnaire. After excluding 18 deaths, 53 refusals, 294 inaccessible participants, and 05 incomplete data entries, we analysed the data of the 1217 respondents. The average physical domain score decreased significantly from baseline to follow-up, whereas a significant increase in average scores has been observed in other domains at the follow-up (p<0.05). GEE equation shows after adjusting for other factors, older age, female gender, higher education, higher family income, hospital admission during COVID-19, and the number of comorbidities were significantly associated with changing individuals’ QoL scores. Monthly family income >60000 BDT, being married and having no previous vaccination history are significant in reducing people’s QoL scores in the psychological domain. On the other hand, age, employment status, monthly family income, marital status, smoking history, and COVID-19 reinfection were significantly associated with altering an individual’s QoL scores in the social domain. The overall QoL of COVID-19 recovered people improved in all domains after 18 months, except the physical realm. Participants’ age, employment status, family income, marital status, smoking history, comorbidities, COVID-19 vaccination, and COVID-19 reinfection were responsible for altering people’s QoL index.
Cyclone Freddy and its impact on maternal health service utilisation: Cross-sectional analysis of data from a national maternal surveillance platform in Malawi
Authors: Twabi Hussein H. , Jafali James , Mndala Leonard , Riches Jennifer , Monk Edward J. M. , Phiri Deborah , Makuluni Regina , Gadama Luis , Kachale Fannie , Bilesi Rosemary , Mbewe Malangizo , Likaka Andrew , Chapuma Chikondi , Kumwenda Moses , Maseko Bertha , Ndamala Chifundo , Kuyere Annie , Munthali Laura , Henrion Marc Y. R. , Msefula Chisomo , Lissauer David , Odland Maria Lisa
Published: August 2024

Climate change poses a significant threat to women’s health in sub-Saharan Africa, yet the impact of climate change on maternal health is rarely reported in the region. Using an existing Maternal Surveillance Platform (MATSurvey), we estimated the immediate impact of Cyclone Freddy on maternal health care service indicators in Malawi. We analysed facility-level data for pregnant women up to 42 weeks post-partum using the national MATSurvey database. We compared incidences of service utilisation before (1 January to 19 February 2023) and after (20 February to 30 March 2023) the cyclone using a negative binomial regression approach. Between 1 January and 30 March 2023, a total of 37,445 live births, 50,048 antenatal clinic attendances, 23,250 postnatal clinic attendances, 84 maternal deaths, and 1,166 neonatal deaths were recorded by 33 facilities in the MatSurvey database. There was an immediate reduction in service utilisation in the post-cyclone period, including the postnatal attendance per week (pre-cyclone median: 355.0 [IQR 279.0–552.0], post-cyclone median: 261.0 [IQR 154.3–305.5], RR 0.56 [95% CI 0.44–0.71, p <0.001]) and the antenatal attendance per week (pre-cyclone median: 860.0 [IQR 756.5–1060.0], post-cyclone median: 656.5 [IQR 486.5–803.3], RR 0.66 [95% CI 0.55–0.78, p <0.001]). Stratified analyses by geographical zones revealed a stronger reduction in postnatal clinic attendance in the Southwest (RR 0.50 [95% CI 0.29–0.85, p = 0.010]) and the North (RR 0.29 [95% CI 0.15–0.56, p <0.001]). Cyclone Freddy resulted in an immediate decline in utilisation of maternal health services in cyclone-affected regions in Malawi. We observe evidence of catastrophic climate events impacting on the healthcare of women and their babies. Policymakers, researchers, and health systems need to ensure that essential women’s health services are maintained during these events and improve measures to support service resilience in the face of climate change.