bluuebunny/crossref_metadata_2025 huggingface dataset:
Un método topológico para el análisis de complejidad de series de tiempo
Authors: Rodriguez-Torres Erika , Itzá-Ortiz Benjamín A , Menéndez-Conde Lara Federico , Tetlalmatzi-Montiel Margarita , Villarroel-Flores Rafael
Published: July 2021

En este art´ıculo se propone un m´etodo basado en topolog´ıa algebraica para el an´alisis de colecciones de series de tiempo simult´aneas. Cada serie de tiempo corresponde a una variable. Se construye la matriz de correlaci´on de las variables y la red con pesos en las aristas asociada a dicha matriz. A trav´es de variar un par´ametro p entre 0 y 1, se obtiene una filtraci´on de complejos simpliciales. El an´alisis de las cavidades del complejo simplicial se realiza por medio de estudiar los cambios de los n´umeros de Betti de los complejos de la filtraci´on. Mediante experimentos computacionales, obtenemos resultados que sugieren que en el caso de que la matriz de correlaci´on provenga de series de tiempo simult´aneas que modelen un fen´omeno natural, la complejidad de las variaciones de los n´umeros de Betti es mucho menor que cuando la matriz de correlaci´on es aleatoria.
Suicidal ideation in LGBT youth: a literature review
Authors: Santoyo-Báez Cynthia Y. , Pérez-Hernández Elizabeth A. , Orozco-Ramírez Luz A.
Published: July 2021

A review of the literature on experiences and meanings surrounding suicide ideation in LGBT youth was conducted. It was found that a large part of the studies were carried out in Anglo-Saxon populations that tended to compare "heteronormative" with "non-heteronormative" populations, through eminently quantitative designs, where the main results were greater vulnerability in comparison to the heterosexual population, internalized homophobia and rejection of one's own sexual orientation. Social and family vulnerability that fed the experience of diverse violence in different areas of their lives. In addition, alcohol and drugs were predictors of suicidal ideation. These living conditions favored mood disturbances and affected mental health, as well as a tendency to develop self-injurious behaviors. However, family and social support were protective against suicidal ideation. Few authors used the recognized categories within the LGBT community to describe their participants, the category most commonly used was "non-heteronormative population", tending to reproduce heterosexist models. Most of the papers on experiences and meanings did not give their participants a voice.
Medical Practice in the COVID-19 Crisis, an Unsafe Practice
Authors: Omaña-Covarrubias Arianna , Moya- Escalera Adrián , Pimentel Pérez Maribel , Ruiz-Vázquez Oscar F.
Published: July 2021

The situation humanity is currently experiencing is an unforeseen event for which we were not prepared. Unquestionably, the health systems in the world collapsed along with the increase in positive cases of COVID-19. Medical personnel and members of other health care disciplines did not have the necessary training to carry out the necessary protection when dealing with infected patients, however, it was work that had to be done. The death of the first doctors was the turning point at which it was evident that high security measures were required, as well as sufficient training for them to continue their work. Despite the measures implemented, contagion remained a reality. Added to this, at least in our country, the response of the population, which in many cases has been negative, accompanied by attacks on staff, damage to infrastructure and violation of the fundamental rights of other patients. The objective of this article is to present the current situation and help to create awareness of the risk that doctors and other health workers experience in their day to day, since the beginning of this pandemic.
Bioethics: Care of the elderly with Parkinson
Authors: Fernández Fernández Georgina Lorena , Rodarte García Raúl , García Hernández Joaquín
Published: July 2021

Over time, older adults become more vulnerable and undergo physical and mental changes that make them much more fragile. Diseases such as arthritis, osteoporosis, diabetes, eating imbalances, heart ailments, hearing, visual and nervous system problems appear that affect their quality of life, as well as their family environment. In this context, for doctors and the family, the task of caring for a patient with Parkinson's is not easy, it implies medication, as well as the need to involve values, principles and ethical beliefs when caring for them. In this sense, it is necessary to reflect on professional and non-professional care in patients with Parkinson's in a care that must be based on respect, tolerance, patience and solidarity. Therefore, it is bioethics that promotes these attitudes of compassion and empathy towards older adults in the medical and family spheres with the aim that they can live this stage of their life with greater optimism and hope.
Moodle como sistema de gestión de aprendizaje
Authors: Sánchez-Martínez Diana Verónica
Published: July 2021

LMS, por sus siglas en inglés refiere a Learning Managment System y traducido al español refiere a un sistema de gestión del aprendizaje, mismo, que actualmente es empleado para administrar cursos inteligentes ya que entre sus diversas funciones se encuentran, administrar datos complejos, son de fácil acompañamiento, generan informes, son flexibles, modernos, funcionales, de fácil acceso, promueven un aprendizaje consistente, son para todo público, permiten visualizar el progreso de estudiantes y emplear materiales interactivos.

Existen dos principales tipos de LMS: Software libre y comerciales. Los primeros suelen ser claroline, dotLRN, dokeos y Moodle. Los comerciales son Atutor, Blackboard, WebCT y QSMedia, entre otros.

El Moodle permite capacitar en línea a través de una filosofía basada en constructivismo social, desarrolla un sistema eficaz y ordenado en un mismo sitio, cuenta con un sistema de autentificación fácil de alumnos. Permite emplear diversos recursos como: cursos, categorías, actividades, materiales, elecciones en línea, comunicación, estadísticas, eventos, perfil de usuario, cuentas de usuario y roles.

Las actividades que se pueden implementar con Moodle son chats, talleres, foros, evaluación, tareas, encuestas y videoconferencias
Responsabilidad social universitaria: analizando la meta de formación
Authors: Pérez-Herrera Rubén , Carlson-Morales Clara
Published: July 2021

La presente contribución, tiene como objetivo examinar las preguntas y principales evidencias que son parte del área de Formación en un autodiagnóstico de Responsabilidad Social Universitaria, para lograrlo se realizó una recopilación de indicadores con base en la Matriz de URSULA (2016), ANFECA (2016) y RSU PRME (2018). Como resultado, se identificó un total de tres metas, ocho categorías y 37 indicadores que permiten medir la ejecución de las iniciativas en una institución educativa, por lo que se concluyó que el diseñar un autodiagnóstico es un paso indispensable como base de una planeación estratégica integral.
Responsabilidad social universitaria: bajo la lupa el área de impacto de la cognición
Authors: Bernal-López Carlos , Carlson-Morales Clara
Published: July 2021

Objetivo: Identificar y analizar la Responsabilidad Social Universitaria, colocando la lupa en el ámbito de cognición. Método: revisión documental de tipo exploratorio-descriptivo, durante el periodo del 29 marzo al 7 de abril del 2021. Resultados: como parte de los principales resultados, se realizó un diagrama para facilitar la comprensión de los indicadores y evidencias que demanda el quehacer de la investigación en esta área de impacto. Conclusión: se adoptan los indicadores para incluirlos en un autodiagnóstico y se invita a los lectores a sumarse en las iniciativas de la Responsabilidad Social Universitaria que promueven las literaturas que aquí fueron objeto de estudio.
Diseño de sistema mecatrónico para terapia de extremidad superior de niños
Authors: Campos-Ceja Nancy , Gudiño-Lau Jorge , Magaña-Ciprian Silvia , Charre-Ibarra Saida , Alcalá-Rodríguez Janeth , Durán-Fonseca Miguel , Velez-Diaz Daniel
Published: July 2021

Este artículo presenta un diseño de un sistema mecatrónico para apoyar a niños en su rehabilitación de la extremidad superior (hombro, muñeca y mano). Se diseña una interfaz de comunicación empleando la tarjeta arduino para enlazar el sistema mecánico y el software hombre-maquina. Además, se realiza un juego con el propósito de que sea atractivo el sistema mecatrónico y sirva de motivación para que los niños puedan avanzar en sus terapias físicas.

El sistema mecatrónico es diseñado en un software CAD con todos sus componentes, la parte electrónica es realizada con la tarjeta arduino para controlar el avance de las terapias y el juego es creado mediante una plataforma de juegos. El equipo experimental de rehabilitación se diseña con la asesoría de terapeutas y abalado por un centro de rehabilitación de niños con problemas motrices.
MORBIDITY PATTERNS IN UNDERFIVE CHILDREN IN AN URBAN LOW SOCIOECONOMIC COMMUNITY OF GUNTUR CITY IN ANDHRA PRADESH
Authors: Udaragudi Prasada Rao , Rao Nallapu Samson Sanjeeva
Published: July 2021

Background: Retrospective morbidity data helps in prioritizing health conditions according their burden on the child and the family and to plan effective interventions. This study is set to look at the morbidity patterns in in a low area of Guntur city. Methodology: This descriptive study conducted in the service area of the Urban Health Center (UHC) at in Guntur city involved 740 children from 6 randomly selected areas. After taking informed consent, the mothers of the children were subjected to a pretested structured questionnaire on current illnesses, 2 weeks recall of illnesses and illnesses over the last one year. The data is presented in the form of tables and percentages. Significant findings are subjected to tests of significance at 5% Level of Significance. Results: Point prevalence of morbidity was 16.1% among boys and 10.7 % among girls (p value 0.03). Children with morbidity over last two weeks are 12.4% (boys 10.9% & girls 13.9%). Over one year, 52.2% had some illness (Boys 47.2% and Girls 52.8%). The had the maximum illness burden (69.5%) and the infants had the least (31.1%) (p value 0.00000001). Chronic illnesses like asthma, skin conditions etc. were seen in 5% of the children (5.2% male and 4.8% female). 63% of the children were seen in private facilities while 37% were seen in a Govt. health facility. 11.1% of the children were seen only by unqualified practitioners. Discussion: Morbidity in is mainly focused on Acute Respiratory Infections (ARI) and which are the common causes of mortality in this age group. Chronic conditions of childhood may persist into adulthood and can influence both health and academic outcomes. Private sector health facilities including unqualified practitioners are sought after more than Government health facilities. Conclusion: There is an essential need to empower primary caregivers of children especially the mother to recognize early signs of childhood illness and seek appropriate care while also facilitating structural and procedural changes in the public healthcare system.
An addition to the alien flora of Java: the first record of adventive Costus dubius (Costaceae)
Authors: Mustaqim Wendy Achmmad , Setiawan Eka
Published: July 2021

More than 6000 plant species, native and introduced, have been recorded in Java that includes the Costaceae family. In the last few years, several additions of alien Costus species have been published from Java. In 2019, a set of specimens of wild Costus sp. was collected from Institut Pertanian Bogor, Bogor, West Java Indonesia. This species is not similar to any previously recorded wild Costus in Java. Therefore, this research aims to identify the collected specimen and provide a taxonomic account for the species. The morphological description was made from the living plant and the collected herbarium. The description was used to identify the species, supported by field notes and photographs. The result showed that the recently collected specimen belongs to Costus dubius. Before this finding, the plant was only known in cultivation in the Bogor Botanical Garden. Therefore, this finding represents the first record of the adventive population of C. dubius in Java and increases the number of wild Costus in Java into seven species. Further researches on Costus in Java are suggested such as the ecological impact due to the presence of several non-native species.
SOSIALISASI BUDIDAYA TANAMAN PORANG DI LAHAN KOSONG PADA MASYARAKAT DAN PETANI DI KECAMATAN PRAYA BARAT LOMBOK TENGAH
Authors: Ismail Yasin
Published: July 2021

Porang, suatu tumbuhan terna endemik Pulau Lombok sekarang ini mempunyai nilai yang sangat tinggi karena sangat laku sebagai barang ekspor, di samping itu, porang merrupakan  bahan pangan fungsional yang sangat bermanfaat bagi penderita Diabetes melliatus karena kandungan glukomannannya yang tinggi. Sayangnya sekarang tidak banyak masyarakat di Lombok selatan, terutama masyarakat kecamatan Praya Barat yang mengenal tumbuhan tersebut karena tumbuhan tersebut sudah punah atau tidak ditemukan tumbuh liar di tempat itu.   Tujuan dari kegiatan pengabdian kepada masyarakat ini adalah memperkenalkan tanaman porang kepada sekelompok masyarakat di Desa Batujai dan Desa Mangkung Kecamatan Praya Barat dan mengajak mereka  untuk menanam porang di sela-sela tanaman lain atau di lahan kosong. Metode pengabdian yang dilakukan adalah mengundang sekelompok masyarakat termasuk tokoh  masyarakat untuk diperkenalkan tentang tanaman porang, manfaatnya dan nilai ekonomi serta cara membudidayakan porang pada kondisi tanah dan iklim setempat. Selanjutnya dilakukan pembentukan kelompok petani porang untuk smenjadi kelompok tani porang di desanya. Hasil dari pengabdian ini menunjukkan bahwa sebagian besar anggota masyarakat atau petani di Desa Batujai maupun di Desa Mangkung sangat anthusias mengikuti program sosialisasi tersebut. Ternyata tidak satupun dari anggota masyarakat yang mengenal tanaman porang. Mereka belum bisa membedakan porang dari iles-iles (lombos) ataupun dengan suweg (gawok). Dengan melihat potensi nilai ekonomi dari porang, sebagian besar masyarakat yang mengikutu pertemuan sangat anthusias menjadi petani penanam porang. Mereka berjanji segera membentuk kelompok tani khusus penanam porang agar mudaah mengakses pembinaan dari desa maupun dari lembaga-lembaga yang terkait frngan pengembangan tanaman porang. Sayangnya tanaman tanaman porang tumbuh hanya pada bulan-bulan tertentu, (nusim hujan) sehingga pada saat pelaksanaan kegiatan ini tidak bisa dilakukan demontrasi plot, karena porang hanya tumbuh pada musim hujan dan mengalami dormansi pada musim kemarau. Namun hal ini di atasi dengan mengunggah informasi online.
Simulating the dispersion of poisonous organic chemical compounds in wastewater treatment process through the active sludge method using the TOXChem model
Authors: Seyyed Roohollah Masoomi , Mostafa Azizi , Reza Aghlmand , Mohammad Gheibi , Zahra Kian
Published: July 2021

Naturally, microorganisms decompose the organic material existing in nature, both in the presence or absence of oxygen. The majority of materials such as poisonous chemical compounds, heavy metals, would prevent the treatment process from taking place, lead to the entry of these contaminants into the environment results in the emergence of numerous diseases. In the present study, using the TOXChem4.1 simulation model, attempts were made to simulate a wastewater treatment plant and then assess the dispersions of contaminants including 1,2-Dimethylnaphthalene, 1,3-Dinitropyrene, 1,6-Dimethylnaphthalene, 1,6-Dinitropyrene, and 17a-ethinylestradiol (EE2) in concentrations of a common scenario. The results of computer simulations showed that the EE2 contaminant is of the highest percentage of decomposition among others, due to its wider chemical structure. Consequently, it is clear that such contaminant is of the highest mass in the sludge exiting the treatment plant. In addition, the results of the simulations demonstrated that the highest volumes of gaseous pollutants take place in the modulation and initial sedimentation units.
Scientists' Warning to Humanity on Threats to Indigenous and Local Knowledge Systems
Authors: Fernández-Llamazares Álvaro , Lepofsky Dana , Lertzman Ken , Armstrong Chelsey Geralda , Brondizio Eduardo S. , Gavin Michael C. , Lyver Phil O'B. , Nicholas George P. , Pascua Pua'ala , Reo Nicholas J. , Reyes-García Victoria , Turner Nancy J. , Yletyinen Johanna , Anderson E. N. , Balée William , Cariño Joji , David-Chavez Dominique M. , Dunn Christopher P. , Garnett Stephen C. , Greening (La'goot) Spencer , (Niniwum Selapem) Shain Jackson , Kuhnlein Harriet , Molnár Zsolt , Odonne Guillaume , Retter Gunn-Britt , Ripple William J. , Sáfián László , Bahraman Abolfazl Sharifian , Torrents-Ticó Miquel , Vaughan Mehana Blaich
Published: July 2021

The knowledge systems and practices of Indigenous Peoples and local communities play critical roles in safeguarding the biological and cultural diversity of our planet. Globalization, government policies, capitalism, colonialism, and other rapid social-ecological changes threaten the relationships between Indigenous Peoples and local communities and their environments, thereby challenging the continuity and dynamism of Indigenous and Local Knowledge (ILK). In this article, we contribute to the “World Scientists' Warning to Humanity,” issued by the Alliance of World Scientists, by exploring opportunities for sustaining ILK systems on behalf of the future stewardship of our planet. Our warning raises the alarm about the pervasive and ubiquitous erosion of knowledge and practice and the social and ecological consequences of this erosion. While ILK systems can be adaptable and resilient, the foundations of these knowledge systems are compromised by ongoing suppression, misrepresentation, appropriation, assimilation, disconnection, and destruction of biocultural heritage. Three case studies illustrate these processes and how protecting ILK is central to biocultural conservation. We conclude with 15 recommendations that call for the recognition and support of Indigenous Peoples and local communities and their knowledge systems. Enacting these recommendations will entail a transformative and sustained shift in how ILK systems, their knowledge holders, and their multiple expressions in lands and waters are recognized, affirmed, and valued. We appeal for urgent action to support the efforts of Indigenous Peoples and local communities around the world to maintain their knowledge systems, languages, stewardship rights, ties to lands and waters, and the biocultural integrity of their territories—on which we all depend.
“Weaving” Different Knowledge Systems through Studying Salience of Wild Animals in a Dryland Area of Argentina
Authors: Campos Claudia M. , Moreno M. Carolina , Cappa Flavio M. , Ontiveros Yamila , Cona Mónica I. , Torres M. Laura
Published: July 2021

The current biodiversity conservation framework explores “nature-people” relationships, recognizing culture's central role. This study aimed to combine local knowledge with scientific ecological data to better understand the relationships between wild animals and local people. We worked in a village (Los Baldecitos) located in the area of influence of Ischigualasto Provincial Park (San Juan, Argentina). We conducted 20 free listing interviews and 12 semi-structured and open ones. We analyzed how the overall salience of different species (established through free listing and cognitive salience index) can be explained by ecological (measured through species occupancy models) and cultural (expressed in interviews) aspects of salience. The cognitive salience index and estimated animal occupancy showed a positive correlation, although it was not statistically significant (Spearman's Rho = 0.48, P = 0.095, N = 17). This could mean that cultural aspects (faunal uses, perception related to attitudes and to nature conservation) were relevant in explaining overall salience. Ten species had the highest and most statistically significant salience and were recorded by camera traps. Some of them share spaces with people (village, water points, corrals, and domestic animal areas), and others were less likely to share habitats where people are present. Wild species have cultural value related to uses and acceptance due to material (tangible benefits, ecological functions) and non-material (affectionate, emotional, aesthetic, presence in oral expression) values. Two carnivores elicited negative reactions because of their predatory damage to domestic animals. This study demonstrates methods to interweave local and scientific knowledge to understand people-nature relationships in context.
A Short Review on Fly Ash, Rice Husk Ash and Rice Husk Composites
Authors: Kunbithop Aniket Mahadeo
Published: July 2021

Fly ash is generated during the combustion of coal and rice husk ash is generated by the combustion of rice husk for energy production. Fly ash is industrial waste and rice husk ash is agricultural waste that is widely available worldwide. The utilization of fly ash, rice husk and rice husk ash in various applications has done a great deal to solve the waste problem. The present paper gives a short review of the utilization of fly ash, rice husk and rice husk ash as a composite material. The developed composite material is used in various applications, such as in the automobile industry and in other applications
A Study on Income as a Determinant of Buying Decision-making Styles
Authors: Suvadarshini Adyasha , Mishra Bidhu Bhusan
Published: July 2021

The following paper attempts to understand if income determines the buying decision-making styles of consumers in Bhubaneswar, the capital city of Odisha, a state located on eastern India. A total of 103 respondents of Bhubaneswar were chosen by using the Mall intercept method. The samples were classified into three groups based on their average annual family income such as High Income, Middle Income and Low Income groups. Exploratory Factor Analysis was carried to identify the decisionmaking styles. ANOVA was employed to compare the shopping styles of these three income sub-groups. Results indicate that differences in consumer shopping styles exist among the income sub-groups. Findings of the study can be used by marketers for segmentation, targeting and positioning of retail shoppers which may facilitate them to compete efficiently. It is recommended that different income sub-groups should be viewed as distinct consumer segments and strategies should be formulated to cater each segment effectively.
Algoritma Apriori Untuk Penentuan Assosiasi Penjualan Barang
Authors: Wiryawan Calvin Ivan , Utami Yustina Retno Wahyu , Nugroho Didik
Published: July 2021

The increasing of selling basic needs make the company has to provide a lot of goods. The data will be growing up with increasing the transaction at Sari Bumi store. All this time, the selling basic needs at Sari Bumi Store unstructured well so that needed an application with produce important information that can decide marketing strategies. In this research, Apriori algorithm is used to determine association rules. This method was chosen because it is one of the classic data mining algorithms to look for patterns of relationships between one or more items in one dataset. A priori algorithms can help companies in developing marketing strategies. The result of this research is combination between 4 item set with a minimum support of 30% and minimum confidence of 60%.Keywords: sale, staple, apriori algorithm
Sistem Pakar Diagnosa Virus Corona Dengan Metode Naïve Bayes
Authors: Nugroho Fareza Aditiyanto , Solikin Arif Fajar , Anggraini Mutiara Dwi , Kusrini Kusrini
Published: July 2021

Humans being are faced with non-natural disasters which have bad effect for population on the world. This non-natural disaster is called Corona Virus Disease (COVID-19). This COVID-19 will become a pandemic in 2020. This types of COVID-19 is coming from the Orthocronavirinae. It belongs to the Coronaviridae and the Nidovirales. This type of that virus has caused some disease to birds, mammals and also human being. Therefore, the research was conducted. The result of this research will give the information about system which related the classification human being according to their transmission to the body. This research used naïve bayes method. The result of this research is diagnostic system with the level of accuracy 94%. Thus, COVID-19 diagnostic expert system used to know the level of COVID -19 infections to human being. It can help the user knowing the next treatment.Keywords : Expert System, Naïve Bayes, Coronavirus, Covid-19
Ripensare la penisola iberica come zona di traduzione
Authors: Gimeno Ugalde Esther
Published: July 2021

This contribution aims to outline the links between Iberian Studies and Translation Studies, seek new points of connection and reflect on the advantages of a more intense disciplinary approach. This chapter contends that the Spatial Turn, that is, the growing concern for space and the new ways of understanding it from the social sciences and the humanities, has had important epistemological and methodological repercussions in Iberian Studies and also, although to a lesser extent, in Translation Studies, making space a common element that enables and justifies a closer dialogue between these disciplines.
Maragall e il capovolgimento della mitografia dell’iberismo
Authors: Grilli Giuseppe
Published: July 2021

The aim of this chapter is to provide a survey of the concept of Iberian imperialism and Iberian imperialist mythography through the examination of texts by Joan Maragall, Eugeni d’Ors and Fernando Pessoa. The Iberian imperialism is a theoretical and historiographical place that we can understand as part of the external history of the phenomenon or ideality, but also as the form and content of a constant working in the immaterial culture of different countries, of cultures with linguistic expression at the same time close and differentiated.
Decree for the Descendants of the Gamoroi from the Area of Palazzolo Acreide
Authors: Mignosa Valentina
Published: July 2021

Decree engraved on a bronze tablet in a fragmentary state found in the area of Palazzolo Acreide and now preserved at the Metropolitan Museum. The text reports mention of a series of privileges (ateleia/isoteleia; enktesis) granted to an individual or a group by another polis (now lost) in which the group of gamoroi – known from the sources as landowners belonging to the Syracusan aristocracy – must have had a central role. The decree has been dated by most scholars between 491 and 485. However, from the palaeographic point of view, there are several elements that would allow us to date it to the end of the 6th century BC.
Thasian Laws Concerning Wine and Vineyards
Authors: Perucca Alessandro
Published: July 2021

Engraved on this epigraph from Thasos are two laws promulgated within a short period of time between the end of the fifth and the beginning of the fourth century BC. Both deal with viticulture and the production of and trade in wine, a subject that is not new in Thasian legislation and which must have represented an important economic sector for the island. It seems clear that the main purpose of these laws was to prevent fraud concerning quantity, quality or terms of sale of the wine, although the loss of large sections of the inscription makes a complete understanding difficult.
Assessment of the Algorithms for Diagnostics and the Possibilities of Treating Patients with a Penile Dysmorphie Disorder
Authors: Kornyenko Oleksii , Scherbak Mariia , Turchak Mykola
Published: July 2021

The article discusses issues related to the choice of diagnostic algorithms and planning tactics for treating patients with penile dysmorphophobia. The psychological characteristics of this group of patients, methods of diagnosis, psychotherapy correction and the choice of surgical tactics are sounded.

The manifestations of penile dysmorphophobia and dysmorphomania, as disorders of a deeper level, are considered as an integrative problem solved from the standpoint of urology, psychotherapy, and aesthetic surgery. In conjunction with an andrologist, the involvement of a psychotherapist and, if necessary, a psychiatrist is required. At the initial stages of working with a patient, narrowly focused psychotherapy is used. The next level of correction is cognitive behavioral psychotherapy (CBT) with the technique of “exposure and prevention of reactions” or “cognitive restructuring”. The “mindfulness CBT” technique is considered important for teaching the patient the ability to stop subjective perception of personal experiences.

To consolidate the result, individual hypnosuggestational therapy and group (family) psychotherapy are used. The indications for surgical enlargement of the penis are divided into medical, functional and aesthetic. Penile dysmorphophobia is an aesthetic indication for surgery. Contradictions in carrying out such interventions include the lack of standardized methods with a high positive prognosis, overestimated patient expectations, and the lack of a result to improve a man’s self-esteem even with a positive result of the operation.

The clinic of the Department of Sexopathology and Andrology of the State Institution «Institute of Urology of the National Academy of Medical Sciences of Ukraine» uses a ligamentotomy technique to lengthen the penis and implant a polypropylene mesh under the superficial fascia of the penis to thicken it. For patients with manifestations of penile dysmorphophobia simultaneously with severe forms of erectile dysfunction, a number of operations have been proposed for the simultaneous installation of penile implants and augmentation of the tunica albuginea using a graft: corporoplasty with a circular graft, Sliding Technique, modification of the sliding technique (MoST), Multiple-slid-Technique (MuST) augmentation technique.

These techniques are not included in the list of recommendations offered by the urological community; they have high predictable risks of complications requiring urgent explantation of the prosthesis and irreversible loss of penile length.
Analysis of the Effectiveness of Different Types of Shock Wave Therapy for the Treatment of Patients with Chronic Prostatitis
Authors: Migov Vitalii
Published: July 2021

The article provides a comparative assessment of various methods of shock wave therapy used to treat patients with chronic calculous prostatitis and the presence of chronic pelvic pain syndrome. The mechanism of action of the radial pressure wave and focused shock wave therapy is analyzed in detail.

The treatment was carried out in 648 patients divided into 4 groups. In groups 1, 3 and 4, focused shock wave therapy was used using Piezo Wave devices from Richard Wolf of various generations with a piezoelectric generator G-4 (the source of shock waves is a piezoelectric self focusing hemisphere with an energy flux density in the focus area of up to 0,4 mJ/mm2 and pressure up to 82,2 mPa, shock wave pulsation frequency of 8 Hz) and G-10 (the source of shock waves is a piezoelectric self-focusing hemisphere with an energy flux density in the focus area of up to 0,6–2 mJ/mm2 and a pressure of up to 100,0 mPa, shock wave pulsation frequency 8 Hz).

The second group used a BTL-6000 SWT Topline radial pressure wave apparatus with a pressure of up to 5 bar and a frequency of up to 20 Hz. The treatment was carried out according to the method developed on the basis of the Research Institute of Urology of the National Academy of Medical Sciences of Ukraine. The technique includes: the use of shock wave therapy, transrectal photo-electrostimulation and electrophoresis of the rectal preparation fermencol. The technique has long established itself as an effective way to combat chronic pelvic pain syndrome.

The study was conducted in order to establish the most effective method of shock wave therapy and the optimal number and power of impulses per session, as well as the required number of sessions to achieve the maximum effect in relation to pain and in relation to a decrease in the area of prostate gland lesions by secondary changes: fibrosis and calculi, in order to further improve the technique, in connection with the emergence of new models of shock wave therapy devices with improved characteristics on the medical equipment market, article provides a comparative assessment of various methods of shock wave therapy used to treat patients with chronic calculous prostatitis and the presence of chronic pelvic pain syndrome. The mechanism of action of the radial pressure wave and focused shock wave therapy is analyzed in detail.
Perioperative Chemotherapy in the Complex Treatment of Patients with High-grade Bladder Cancer
Authors: Yakovlev Pavlo
Published: July 2021

Chemotherapy (CT) is a method of treating patients with muscle-invasive bladder cancer, most of which present as high-grade cancer, in neoadjuvant or adjuvant setting, to treat or prevent metastatic cancer.

The objective: to determine the place of perioperative PCT in the algorithm of complex treatment of patients with high-grade bladder cancer (HGBC) and its influence on survival rates.

Materials and methods. We performed retrospective analysis of medical histories of 522 patients with HGBC, who were treated in 1998-2016. Using the Kaplan-Mayer statistical method, we did a comparative analysis of the survival of HGBC patients who did and did not undergo perioperative CT as part of a comprehensive treatment.

Results. Perioperative CT was performed in 97 (18.6 %) patients, including neoadjuvant CT in only 4 (0.8 %) patients. Only among stage IV HGBC patients the adjuvant CT demonstrated significant differences towards better survival compared to patients without CT (p=0.004), with a 5-year survival rate of 18 % vs. 4 % in relevant groups. In the treatment of patients with stages I, II and III, no statistically significant differences in survival rates were found. The highest average survival rates of patients receiving PCT were found in patients treated with salvage cystectomy (68 months). Survival of patients after TUR, resection, RCE were similar (37-43 months) and do not differ statistically. The worst survival rates were in patients who did not receive surgical treatment and were treated with CT and radiotherapy only (9 months).

Conclusions. Postoperative chemotherapy significantly improved the survival of Stage IV HGBC patients after surgery, with 5-year survival of 18 % vs. 4 %. The best average survival rates (68 months) were demonstrated in the group of patients after salvage cystectomy.
Modern Algorithm for Diagnosis and Treatment of Diseases in Men That Lead to Infertility
Authors: Nikitin Oleh , Yasynetsky Mykola
Published: July 2021

The problem of sterile marriage provides great importance throughout the world. Infertility is a condition that is accompanied by a number of diseases of the genital organs and systemic diseases of the male or female organism. According to various literary sources, about 50–100 million people suffer from infertility in the world, that is, one out of 5–7 couples of reproductive age suffers from infertility.

The problem of infertility in marriage is of particular importance in the context of the demographic crisis in Ukraine, where the frequency of infertile marriage among married couples of reproductive age is 10,0–15,0 %, and in some regions this indicator is close to 20,0 %. In Ukraine, there are more than 1 million infertile married couples, the male factor in the structure of infertility is about 40-50 % of cases. Most authors point to the polyetiology of male infertility. In its development, a significant role is assigned to such factors as neuropsychic, infectious toxic, congenital and genetic reasons, exogenous and habitual intoxications, ionizing radiation, dysfunctions of the endocrine glands and other internal organs, exposure to temperatures, vascular disorders, damage to the genital organs and their autoimmune lesions.

Infertility is a complex and multifaceted problem, and there are a lot of different questions which need to solve. Particular difficulties arise in determining the treatment tactics in cases where there is a combination of various causes of infertility in a married couple. Opportune examination of partners with using modern hardware, laboratory and genetic methods is very important, and it allows to prescribe an effective treatment.

The use of reproductive technologies significantly expands the possibilities for solving the problem of infertility. However, their main purpose is the birth of a child; treatment of diseases that have led to infertility requires additional efforts.

In this regard, the development of modern methods of diagnosis and treatment of sterile marriage remains one of the actual problems.
Vaginismus: Frequency, Definitions, Diagnostic Criteria, Formation
Authors: Kocharyan Garnik
Published: July 2021

The article deals with the frequency of vaginismus, its definitions and criteria, which are presented in encyclopaedical sources, the International Classification of Diseases, 10th and 11th Revisions (ICD-10 and ICD-11), the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (USA) (DSM-V), as well as in publications made by some authors. It is reported that while ICD-10 presents psychogenic and biogenic variants of vaginismus separately, in ICD-11 the differentiation of sexual disorders into psychogenic and organic ones is cancelled. ICD-11 considers the brain and body as a unity, sexual dysfunctions being caused by an interaction of physical and psychological factors. In this way, a difference between the organic and inorganic is eliminated, organic and inorganic disorders being united.

In ICD-11 vaginismus is reclassified into sexual pain-penetration disorder without dividing it into organic and inorganic forms and has its united code, HA20. The diagnosis “dyspareunia” in ICD-11 is preserved, but it is not divided into inorganic and organic variants. DSM-V uses the term “genito-pelvic pain/penetration disorder”. In this case it means a combined diagnosis, which unites vaginismus and dyspareunia. The decision about expediency of using such a generalized diagnosis in this classification is taken on the ground of the fact that both above sexual dysfunctions are highly comorbid and hardly differentiated from each other. Also the article lists the muscles, involved in the process of contraction in vaginismus, and discusses the possibility of existence of the phenomenon of capture of penis (penis captivus) in people. Besides, sociogenic, psychogenic and somatic factors, which can participate in the formation of the characterized pathology, are listed in detail.
Opportunities for Unsalted Management of the Postoperative Period in Patients with Uncomplicated Ureterolithiasis
Authors: Nikitin Oleh , Roshchyn Yurii , Komisarenko Ihor , Fukszon Oleksandr , Smikhun Sviatoslav
Published: July 2021

When performing surgeries for ureteral stones, ureteral stenting is traditionally performed to avoid obstruction of the ureter in the postoperative period due to edema or stone fragments. Modern technical advances allow ureteroscopy to be performed relatively atraumatically and to avoid routine ureteral stenting, which makes it possible to exclude exacerbations of pyelonephritis caused by reflux, reduce stent costs, improve the quality of life in the postoperative period, and avoid cystoscopy for dentition.

The objective: studying the possibility of non-drainage management of the postoperative period, identifying risk factors for postoperative complications in patients with uncomplicated ureteral stones.

Materials and methods. The analysis of the results of treatment of 198 patients with uncomplicated ureterolithiasis, in whom it was decided to refuse stenting after ureteroscopy, was carried out.

Results. The analysis of the condition of patients in the postoperative period was carried out. To identify the factors influencing the decision on non-drainage management of the patient in the postoperative period, as well as factors that could be predictors of postoperative complications, we analyzed various indicators.

Conclusions. In the case of uncomplicated ureterolithiasis, in most cases (in 68.2 % of patients) in the postoperative period, there is no need to drain the upper urinary tract using a stent. At the same time, in a number of cases – namely in 31.8 % of patients – upon refusal to install a stent, complications arose that significantly influenced the duration and cost of treatment, in some cases requiring an increase in the volume of therapy, additional procedures – installation stent and puncture nephrostomy.
The Spread of Thyroid Diseases and the Algorithm for Diagnosing Thyroid Dysfunction
Authors: Shkala Liubov , Shkala Oleh
Published: July 2021

Diseases of the thyroid gland are considered one of the most common endocrinopathies. This is due to the influence of ecologically unfavorable environmental factors, bad habits, malnutrition, comorbid conditions and genetic predisposition. Determining an algorithm for diagnosing thyroid dysfunction for the timely detection of diseases is expedient and relevant.
The objective: to analyze the state of the spread of thyroid diseases among the population of the Kiev region and to determine the diagnostic algorithm based on the identification of the main clinical syndromes of thyroid dysfunction.
Materials and methods. Among the adult population of the Kiev region, a high level of morbidity and spread of thyroid diseases is recorded. The increase in the number of cases occurred, first of all, due to the newly diagnosed patients with hypothyroidism, thyroiditis. The manifestation of most diseases is associated with the development of thyroid dysfunction. Under the hypothyroidism one can observe and diagnose the following: a syndrome of neuropsychiatric disorders with slowing down of motor activity, decrease in cognitive functions; syndrome of vegetative-trophic disorders with cutaneous mucinosis, polyneuropathy; syndrome of cardiovascular changes with decreased myocardial contractility, slow blood flow, progressive development of atherosclerosis; anemic syndrome; digestive tract syndrome with impaired motor and secretory functions of the gastrointestinal tract; syndrome of hormonal disorders with decreased secretion of thyroid hormones, especially T4, increased levels of TSH (in primary hypothyroidism) or decreased TSH (in secondary and tertiary).
Results. Thyrotoxicosis in patients is determined by an enlarged thyroid gland with the development of: thyrotoxic cardiomyopathy and systolic arterial hypertension; thyrotoxic encephalopathy, syndrome of neuropsychiatric disorders with a predominance of excitation processes, vascular dysfunction; thyrotoxic ophthalmopathy, ectodermal disorders syndrome along with a decrease in TSH production and an increase in the level of free fractions T4, T3.
Conclusions. The algorithm for diagnosing hypofunction and hyperfunction of the thyroid gland provides for: clarification of complaints and anamnesis data, examination of the patient, additional laboratory and instrumental examination, which includes the study of the thyroid status, possible autoaggression, analysis of metabolic processes, assessment of pathomorphological changes in the thyroid gland.
Peculiarities of circulation of interleukins of different classes in multiple pregnancy depending on the method of fertilization and the term of gestation
Authors: Poladich I.V. , Avramenko S.O.  , Malanchuk O.B.  , Kostenko O.Yu. 
Published: July 2021

The article is devoted to the detection of interleukin circulation of different classes in women with multiple pregnancies depending on the method of fertilization and gestational age.The study found that the concentration of pro-inflammatory cytokines IL-1 (126.8 pg/mg) and IL-8 (176.4 pg/mg), determined in the 22nd week of pregnancy in the serum of patients with multiple pregnancies due to using ART, probably exceeded the control group (48.7 and 39.3 pg/mg) and spontaneous multiple pregnancy (49.3 and 40.6 pg/mg). Concentrations of cervical IL-1 and IL-8 were also elevated in pregnant women receiving ART compared with women with spontaneous multiple births and controls. These changes were observed in the dynamics of pregnancy. Under the influence of our recommended therapy, there was a gradual decrease in IL-1 and IL-8, which no longer differed from those of women with spontaneous multiple pregnancies and the control group. Administration of natural micronized progesterone for immunosuppression (normalization of the cytokine profile) to patients with multiple pregnancies due to the use of ART, reduced the incidence of preterm birth (from 83.3 to 43.7%), weakness of labor (33.3 and 21.9%, respectively), PRPO (22.2 and 12.5%, respectively), to reduce perinatal morbidity from 45.5 to 19.7% and mortality from 43.1 to 9.5%, which was not detected in patients with spontaneous fertility.Determining the features of cytokine imbalance in women with multiple pregnancies depending on the method of fertilization provides new approaches to the prevention and treatment of miscarriage, which will benefit mothers in different clinical situations.
Modern views on the prevention of obstetric and perinatal complications in healthy pregnant women (Literature review)
Authors: Nevyshnа Y.V. 
Published: July 2021

This review article provides information on the role of different methods for pregnant women to prepare for childbirth according to the data regarding both foreign and domestic practices in obstetrics. The article highlights the issue of partner support starting from when pregnancy is established and gestation, through to childbirth and the postpartum period. According to the research, it is clear that the physiological course of the pregnancy directly depends on the psycho-emotional state of a pregnant woman, which impacts not only the course of pregnancy and childbirth, but also the condition of the fetus and newborn.The results of the research show that the method of psychophysiological preparation and partner support undoubtedly has a positive influence on the consequent childbirth: the duration of childbirth and the frequency of anomalies during maternity activity are reduced; surgery is performed less; the frequency of cervical and perineum ruptures, as well as the amount of blood loss, are decreased; intrauterine hypoxia and birth asphyxia are less common; and the manifestation of obstetric aggression decreases. Furthermore, the technologies of prenatal preparation are aimed at the demedicalization of childbirth and the minimization of the use of pharmacological drugs which have an ambiguous influence on a parturient, a fetus and a newborn.Therefore, the data mentioned above reveal the role of prenatal preparation methods of married couples for childbirth not only in the reduction of obstetric and perinatal complications in relatively healthy, pregnant women, but also in the choice of anesthesia methods, taking safety and efficiency into account.Unfortunately, the decreased interest toward psychophysiological preparation for childbirth by pregnant women and their partners, as well as medical institutions in general, was revealed while studying the issue of preparation for childbirth.Consequently, prenatal preparation of married couples must be obligatory in the system of obstetric care in Ukraine at all medical levels.