bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of Antifertility Potential of Entada rheedii Spreng Seed Kernel Extract in Female Wistar Rats
Authors: Dawane Jayshree , Thakur Linpadmaja , Suryawanshi Sonali
Published: August 2024

Background: Population growth has created a global dilemma, putting burden on economic, social, and ecological resources. Entada rheedii Spreng (ERS) seeds have many medicinal properties. In folkloric medicine, seeds are used as contraceptives, but no studies available. Aim: To evaluate antifertility potential of ERS seed kernel extract in female Wistar rats. Method: 90 Female Wistar rats with regular oestrus cycles and proven fertility were included. Methanol extract of ERS seed kernel was used in dose of 200 mg/kg and 400 mg/kg by oral route. Part I-Reproductive outcome rats were kept for mating after 8 days’ initial drug treatment which continued for 21 days, number of litters was measured. Mothers were observed for regain of fertility and pubs for teratogenicity. Part II-Animals kept for mating followed by 7 days’ drug treatment, Laparotomy done on the 10th day, number of implants checked and after delivery litter size counted. Part-III Abortifacient effect rats kept for mating. Laparotomy done on day 10, drug treatment was given for 21 days and again laparotomy was done and resorption of implants was measured. Blood withdrawal done from the rats of reproductive outcome for hormonal estimation. Data analyzed with Graph Pad Prism 6. Results: The control rats showed a significant increase in litter numbers compared to treated animal in both the doses of ERS low (P < 0.001) and high (P < 0.001). Pubs appeared normal and reversal of effect in the form of gain of fertility after 21 days of treatment was evident. The treatment with ERS extract resulted in a statistical increase in the resorption index (P < 0.001) suggesting a failure of embryonic development. Anti-implantation and abortifacient action were seen with both doses of ERS. Conclusion: Results show that ERS seed kernel has potential and reversible antifertility effect in female Wistar rats.
Review on Ethno Medicinal Activities of Wild Varieties of Orchids used by the Ethnic Group of Northeast India
Authors: Alam Tahid , Sarkar Bapi Ray , Luitel Pooja Sharma , Gorai Arup Kumar , Dey Ganesh , Umam Abdul Hadi , Rahman Tasrina , Sikdar Debajit , Hussain Ikram , Roy Abhishek Guha
Published: August 2024

Ethno medicine broadly refers to traditional medical practices concerned with the social and cultural impacts of health, sickness, and illness related to healthcare and healing techniques. The Orchidaceae family is one of the world's oldest and largest flowering plant families, with over 800 genera and between 25000 and 35000 species. According to the Indian government, 70% of the population practice traditional Indian medicine. In the Northeastern region, there are almost 200 tribes, and they deal with various kinds of orchids found in this region, which have potential medicinal values and traditional indigenous use, which can be effective against multiple diseases. It is essential to keep medicinal plants and perform studies on various kinds. Many plants have yet to be studied for their numerous medicinal potentials. A multidisciplinary approach is necessary to develop potentially helpful drugs using proper pharmacological investigation.
From a Global Perspective Towards an Integrated Approach for Ophitoxaemia
Authors: Navanita S. K. , Narayana Reddy Karri V. V. S. , Prakash Yoganandam G. , Shanker Kalakotla , Vasanth Raj P.
Published: August 2024

Ophitoxaemia is the medical term that describes an injury induced by a snake bite which can be fatal in the case of venomous snakes. Bleeding, allergic response, necrosis, and bradycardia are symptoms of venomous bite. Snake venom is from a complex mixture of proteins- enzymes, nonenzymatic polypeptide toxins, and nontoxic proteins. Based on the nature of the toxin and type of snake, the toxins are classified into neuro, cardio, and cytotoxins. This comparative study aims to explore and compare the practice of the traditional Ayurveda system and the modern system of medicine for snakebite management. By examining the existing literature and research on both systems, this article will provide insights into their efficacy, safety, and potential for integration.
Hepatoprotective Effect of Ethanolic Extract of Whole Plant of Tephrosia barberi J. R. Drumm. in Paracetamol Induced Hepatotoxicity in Rats
Authors: Sameemabegum S. , Thilagavathi Ramasamy , Kumarnallasivan P. , Sivakumar Thangavel
Published: August 2024

Background: Tephrosia barberi J. R. Drumm is a novel endemic perennial herb belonging to the Fabaceae family. Aim: To investigate the hepatoprotective activity of the whole plant of T. barberi. Methods: Preliminary phytochemical testing and GCMS analysis were done for the ethanolic extract of T. barberi. Initially, acute toxicity experiments were carried out in which five groups of rats (n=3) were administered with 0.5% carboxymethyl cellulose (normal control), ethanolic extract of T. barberi orally (5, 50, 300 and 2000 mg/kg b.w.) for 14 days daily, there was no mortality observed for 24 hr. For the assessment of the hepatoprotective potential, ethanolic extracts of T. barberi (200mg/kg low dose and 400mg/kg high dose) and silymarin (100mg/kg, employed as the reference standard), distilled water (normal control, paracetamol control) was given orally to five groups of rats (n=6) over seven days. All animals were given paracetamol on the fifth day, following the administration of standard and extracts, except for those in normal control. To assess the levels of serum enzymes, proteins, antioxidant indicators, and histopathological analyses, the rats were sacrificed and blood samples, liver homogenate, and liver sections were taken. Results: Rats fed with T. barberi ethanol extract (400mg/kg/day) and silymarin, a standard drug (100mg/kg/day) treated groups had significantly elevated liver serum enzymes such as alanine phosphatase, aspartate aminotransferase, alanine transaminase, total protein and total bilirubin than the intoxicated rats (p<0.01to p<0.001). Furthermore, the effect of antioxidant parameters (GSH, CAT, and SOD) on hepatic tissue showed that ethanol extract of T. barberi (high dose, 400mg/kg) produced improved hepatic function than toxic control rat and exhibited significant action compared to standard drug. Conclusion: The current research findings strongly indicate that T. barberi has promising hepatoprotective potential due to the presence of flavonoids and phenolic compounds.
Development and Characterisation of Curcuminoid Loaded Hydrogel for the Effective Treatment of Diabetic Retinopathy
Authors: Kondeti Durga Prasad , Sundarrajan T.
Published: August 2024

Background: The leading cause of vision loss in individuals with diabetes worldwide is diabetic retinopathy. A curcuminoid-loaded hydro gel has been proposed to improve solubility and ocular permeation. Aim: A gel-based formulation using gellan gum was hypothesised to enhance its bioavailability. The RP-HPLC analysis confirmed curcuminoid isolated from raw turmeric. Methods: By varying the gellan gum concentrations, three different formulations were developed. The developed curcuminoid-loaded gel formulation was further characterised by its FT-IR signature analysis, particle size, zeta potential, morphology and in-vitro release behaviour. Results: The signature analysis results indicate a drug’s signature in the formulation. The study revealed sphere-sized particles ranging from 6387±113 to 4595±184 nm with zeta potential ranging from -21 ±2.29 mV to -19.6 ±3.19 mV. A sustained release pattern was observed by the in-vitro release studies. The results of ex vivo corneal permeation studies indicate that the developed curcuminoid loaded hydrogel have some exposure to the posterior segment of the eye. Conclusion: To conclude the developed curcuminoid hydrogel may provide exposure to the posterior segment of the eye due to its significant corneal permeation property.
Evaluation of Effect of Seed Cycling on Anthropometric, Biochemical, Hormonal and Nutritional Parameters in the Women Diagnosed with Polycystic Ovarian Syndrome – A Cohort Interventional Study Design
Authors: Kour Harpreet , Anitha C. , Ghatnatti Vikrant , Patil Swetha , Kadeangadi Deepti
Published: August 2024

Background: Polycystic Ovary Syndrome (PCOS) is an endocrine disorder of reproductive age group in women and is characterized by obesity, hyper-insulinemia, hyperandrogenism and insulin resistance. Seed cycling has emerged as a potential treatment modality for managing PCOS symptoms. Methods: A total of 290 women diagnosed with PCOS, aged 18-40, and were enrolled in this study after meeting specific eligibility criteria. Participants were randomly divided into two groups: a control group (n=145) and an intervention group (n=145). The control group received a portion-controlled diet along with a daily dose of Metformin 500 mg for 12 weeks. The intervention group followed the same diet but incorporated seed cycling into their regimen. Assessments, including anthropometric measurements, biochemical analyses, hormonal evaluations, and nutritional assessments, were conducted at baseline and after the 12-week treatment period. The Mann-Whitney U test was used to compare outcomes between the two groups before and after treatment, with significance determined at p<0.05. Results: The majority of participants were aged 26-30 years (46.90%), with 60% being non-vegetarian. Among them, 36% were employed, and 14% engaged in physical activity. The intervention group demonstrated significant improvements in anthropometric, biochemical, and hormonal parameters compared to the control group. Notably, there was a decrease in mean energy consumption, carbohydrate intake, and fat intake in the intervention group, while mean protein intake remained unchanged between the groups after 12 weeks. These improvements were statistically significant (p<0.05). Conclusion: The study concluded that women with PCOS showed substantial improvements in anthropometric, biochemical, and hormonal profiles following seed cycling therapy combined with dietary modifications. This suggests that seed cycling, along with a portion-controlled diet, can be an effective strategy for managing PCOS symptoms.
Exploring the Anti-obesity Properties of Corn Silk Extract (CornFit®) in C57BL/6 Mice Induced with Obesity via a High-Fat Diet
Authors: Shivaprasad H. N. , Soni Gaurav , Krishnamani Madhu , Sravani T. , Garaga Machiraju , Manohar D.
Published: August 2024

Objective: The impact of CornFit®, an extract derived from corn silk was assessed on obesity-induced mice subjected to a High-Fat Diet (HFD). Methods: C57BL/6 mice were assigned to seven groups: normal control, HFD control, reference standard and four CornFit® dosage groups. Body weight, food intake, fat mass and metabolic parameters were assessed throughout the study. Biochemical markers, gene expression in liver tissue and histopathological analysis were also performed. Results: Supplementation with CornFit® notably decreased body weight gain, fat mass and enhanced lipid profile compared to the HFD group. It also decreased pro-inflammatory markers and insulin levels while increasing adiponectin and leptin, indicating anti-inflammatory and metabolic benefits. RT-PCR analysis revealed downregulation of lipogenic genes and upregulation of genes involved in fatty acid metabolism and energy expenditure. Liver function tests and organ weights improved in treated groups. Conclusion: CornFit® demonstrates promising anti-obesity potential by reducing fat accumulation, improving metabolic health and modulating related gene expression.
Errata Title: Formulation and Evaluation of Amomum subulatum Leaf Oil Incorporated Pluronic Matrix Type Transdermal Patches in Percutaneous Absorption
Authors: Das Sudip , Sarkar Bapi Ray , Gupta Koushik Sen
Published: August 2024

A matrix type of transdermal patch formulations having different types of hydrophilic, hydrophobic polymer components Diclofenac potassium (Diclofenac K) served as the model drug and penetration enhancer for topical delivery in this research, employing the USP7 apparatus for dissolution studies. Transdermal patches loaded with Amomum subulatum leaf volatile oil (utilized penetration enhancer) were formulated using the solvent evaporation technique, incorporating varying amounts of pluronic F-127 and ethyl cellulose based on 15 formulations designed by the Box Behnken model. The prepared patches underwent evaluation for various physicochemical parameters, including tensile toughness, moisture content, and moisture uptake. In vitro diffusion studies were conducted using the USP7 apparatus dedicated to transdermal drug release investigations. The optimized formulation, F10, exhibited a drug release of 82% over 24 hours in the in vitro diffusion study. All the transdermal matrix-type formulations demonstrated satisfactory results, indicating that the developed matrix-type transdermal patch, containing different polymers and the A. subulatum leaf volatile oil penetration enhancer, holds potential for transdermal delivery in the treatment of pain and swelling.
APPLICATION OF THE METHOD OF BIOLOGICALLY ORIENTED BONE MODELING AS A WAY TO RECREATE THE NATURAL STRUCTURE AND STRENGTH UNDER EXPERIMENTAL CONDITIONS
Authors: Avanisyan Vazgen , Dolgalev Aleksandr , Sergeev Yuriy , Garazha Sergey
Published: August 2024

The relevance. Bone is an organic mineral composite with a complex structure. Bone modeling for different experiments also involves different design and application of loads. The applied additive technologies, in conjunction with the necessary equipment, help to recreate the structural features of the jaw bones in order to study the future implantation or position of the orthopedic structure. Digital dentistry is not always able to simulate all the biological nuances, in such cases models and templates made in advance by 3D printing from a material with similar strength characteristics come to the rescue.
The aim of the study is to evaluate the strength properties of natural bone tissue using the example of the lower jaw of a ram with further modeling of bone from a material with similar strength characteristics.
Materials and methods. The objects of the study were selected samples of the mandible of a laboratory animal, as well as imitation models made of 3D printing material by photopolymer deposition in the form of cubes, simulating the cortical and spongy structures of bone tissue. The test samples were placed in the screw holder of the universal GOTECH Al 7000S testing machine with the determination of the stress and load limit of the mandibular imitation models simulating bone tissue, pre-printed on a 3D printer with certain parameters such as the density of the layers, their number, the type of polymer material from which they were made, obtaining similar models jaws made of selected materials and comparison of their characteristics with the biological object of study.
Results. The determination of the optimal material obtained using the photopolymer printing method made it possible to obtain the most effective and similar in characteristics to bone tissue model suitable for a more detailed study of the behavior of bone tissue, which allows using this material as a phantom material in determining load protocols.
Conclusion. Quantitative results of stress tests make it possible to predict the strength results of a real bone, while not spending time and material resources on identifying and predicting risks.
Effect of sequential cleavage and blastocyst embryo transfer compared to single cleavage stage embryo transfer on assisted reproductive technology outcome: An RCT
Authors: Homayoon Nahid , Arabian Sahereh , Mangoli Esmat , Bayati Fatemeh , Eftekhar Maryam
Published: August 2024

Background: Assisted reproductive technology (ART), offers hope for many infertile couples by increasing the chance of successful pregnancy. The success of in vitro fertilization depends on various factors, in which embryo transfer (ET) is one of the critical steps influencing in vitro fertilization success rates. Extended embryo culture and blastocyst-stage ET have been considered in ART due to their potential benefits including improved implantation rates.
Objective: This study aimed to compare the outcomes of sequential ET vs single cleavage-stage ET in women undergoing a fresh ET cycle with a limited number of embryos.
Materials and Methods: This randomized clinical trial was conducted on 140 women undergoing infertility treatments and candidates for fresh ET at the Research and Clinical Center for Infertility, Yazd, Iran from August 2023 to January 2024. Women with a number of embryos from 2–5 (≥ 2 and ≤ 5 available embryos) were randomly divided into 2 groups: One group underwent sequential ET (one cleavage-stage ET followed by one blastocyst ET) and the other group underwent single-step 2 cleavage-stage ET. The primary outcome was clinical pregnancy, and the secondary outcome included chemical pregnancy and early abortion rates.
Results: Our findings showed significantly higher rates of clinical (33.5% vs 13.6%, p = 0.003) and chemical (41.3% vs 18.2%, p = 0.004) pregnancies in the sequential ET group compared to the single-step cleavage ET group. The early abortion rate was higher in single-step cleavage ET (13% vs 44.4%, p = 0.053).
Conclusion: Sequential fresh ET is a useful choice in women who have a limited number of embryos and can improve ART outcomes.
Key words: Blastocyst transfer, In vitro fertilization, Embryo transfer.
Investissement Direct Étranger, transition energétique et degradation de l’environnement : évidence des pays d’Afrique subsaharienne
Authors: Afo-Loko Owodon
Published: August 2024

L’objectif – L’objectif de cette étude est d’analyser la relation entre les investissements directs étrangers (IDE), la transition énergétique et la pollution de l'environnement en Afrique subsaharienne sur la période 1985 à 2020.
Conception/méthodologie/approche – Diverses approches économétriques ont été utilisées afin d’obtenir des résultats robustes. Le test de dépendance transversale a été effectué et les résultats ont confirmé la présence d'une dépendance transversale entre les variables, ce qui a permis l'utilisation du test de racine unitaire de seconde génération. L'analyse a été réalisée à l'aide de la méthode de Driscoll et Kraay, qui permet de traiter l'endogénéité, l'autocorrélation et l'hétéroscédasticité.
Résultats : Les résultats montrent que l’hypothèse << pollutio haven>> est confirmée et que l’utilisation des énergies renouvelables qui mesure la transition énergétique diminue la pollution environnementale. Aussi l’éffet couplé des investissement direct à l étranger et les énergies renouvelable minimise la pollution de l environnement .La densité de la population, le commerce et le produit intérieur brut augmente la pollution de l'environnement.
Originalité/valeur –Cette étude contribue à la littérature existant sur l’analyse de la relation entre investissement direct à l’étranger et la pollution de l’environnement ou énergies renouvelable et pollution de l’environnement en portant un regard particulier sur l’effet couplé de l’investissement direct à l’étranger et l’usage des énergies renouvelables sur la qualité de l’environnement. Nous pouvons suggérer à partir de ces résultats que d’ample efforts devraient être faits afin d'augmenter le taux d'investissement direct étranger dans les pays d'Afrique subsaharienne, en particulier l'attrait des technologies vertes qui peuvent aider à produire davantage d'énergies renouvelables.
Constitutional and Legal Foundations of the Status of Man and Citizen in the Digital State
Authors: Cherepanova Tatyana S. ,   Postgraduate Student of the Law Faculty of the Dostoevsky Omsk State University
Published: August 2024

The purpose of our work was to generalize and analyze the constitutional and legal foundations of the status of a person and a citizen in a digital state. The views of scientists on: legal regulation of the legal status of the individual in the conditions of digital transformation of public administration, basic human and civil rights and freedoms that form the basic basis of the legal status of the personality of the information society in Russia are considered.
The 30th Anniversary of the Parliament of Russia
Authors: Kara-oll Sholban V. ,   Deputy Chairman, Deputy of the State Duma of the Federal Assembly of the Russian Federation, Ivanov Ivan V. ,   Associate Professor of the Graduate School of Business
Published: August 2024

The article discusses the development of parliamentarism in Russia in the light of the 30th anniversary of the Federal Assembly of the Russian Federation. The study examines certain key aspects of the activities of Parliament, the tasks and prospects for improving its work, which are related to the development of the constitutional and legal status of a deputy and senator; the role and significance of Parliament in a unified system of public power, in the system of interaction with the Government of Russia; the opportunity to improve the quality of legislative activity. It is proposed to legislatively develop provisions on the interaction of a deputy with voters, the possibility of them sending proposals on the agenda of meetings with people’s representatives. Attention is paid to the possibility of revising legislative acts of the Soviet period, the implementation of which is virtually impossible.
Pension Relations: Succession and Development of Legal Views of A.D. Zaykin
Authors: Machulskaya Elena E. ,   rofessor of the Department of Labor Law of the Law Faculty of the Lomonosov Moscow State University
Published: August 2024

The article is devoted to the analysis of scientific conclusions made by A.D. Zaikin in his dissertation for the degree of Doctor of Law ‘Legal relations on pension provision in the USSR’, defended in 1974 at a meeting of the Academic Council of the Faculty of Law of Lomonosov Moscow State University. Legal relations on pension provision, as in the Soviet period, remain distributive, state-alimentary obligations guaranteed by the Constitution of the Russian Federation. In these legal relations, the state is still an obligated party, and an individual (or family) is an authorized party, which can’t be denied a pension if the conditions established by law are met, regardless of whether there is a shortage of funds in the Pension and Social Insurance Fund (SFR). This deficit is covered annually from the federal budget. There forms of the pension system that took place in the post-Soviet period do not reduce the reliability and scientific validity of the conclusions made in A.D. Zaikin's dissertation. His works in the field of social security together with the works of other outstanding Soviet scientists — V.S. Andreev, R.I. Ivanova, V.K. Mironov, V.A. Tarasova laid the foundation of the University school of social security law.
REFORMATION OF THE INSTITUTION OF INHERITANCE IN RUSSIA: THE LEGAL RETROSPECT (THE LATE 19TH TO THE EARLY 20TH CENTURY)
Authors: Mandryka Elena V. ,   Associate Professor of the Department of Legal Disciplines
Published: August 2024

The study presents a retrospective of inheritance legislation at the end of the 19th — beginning of the 20th centuries, and analyzes the legal acts of the period under review. Conclusions are drawn about the terms used in a specifi c historical era regarding inheritance, the grounds of inheritance, the circle of heirs, and the order of inheritance according to the law.
Criminological Characteristics of the Personality of an Escaped Criminal
Authors: Karpov Andrey A. ,   Senior Lecturer of the Department of Penal and Criminal Law of the VRI of the FPS of Russia, Ryabykh Sergey B. , Scherbakov Andrey V. ,   Senior Lecturer of the Department of Security Administration,   Head of the Department of Security Administration and Criminal Intelligence and
Published: August 2024

The analysis of statistical indicators, informational letters, analytical reviews of the management of the regime and supervision of the Federal Penitentiary Service of Russia for the period from 2017 to 2021 allowed the authors to compile an average criminological portrait of a convict who escaped from supervision. The authors believe that, having information in the professional activity of the analyzed individual characteristics of convicts who have escaped from supervision, they will further provide an opportunity to rationally and effectively organize educational and preventive work with them to prevent and suppress escapes from supervision.
Identification of needs of family members of surgical intensive care unit patients: a cross-sectional study
Authors: Öztaş İsmail , Yava Ayla , Koyuncu Aynur , Kaptanoğlu Sema
Published: August 2024

Objectives: It is aimed to determine the needs of family members whose patients are hospitalized in surgical intensive care unit.
Methods: Data were collected from 150 family members hospitalized in the surgical intensive care unit of a large university hospital. Data were collected using the Patient Relative Introduction Form and the Patient Relatives' Needs Scale in Intensive Care Units (CCFNI=Critical Care Family Need Inventory).
Results: Of the participants, 25.3% are female, while 68.7% are married. While 71.3% of the participants stated that they received information from their patients in the days following admission, only 4% of the participants were informed about intensive care; all participants stated that they were not given any pamphlets or brochures about intensive care. Among the healthcare professionals, doctors were identified as the individuals who establish solid and reliable communication, with 53% of the participants.
Conclusions: It has been determined that the needs of patient relatives are very important, with the most crucial need being to know the patient's chances of recovery. Meeting all the physical, mental, and psychosocial needs of patients and their relatives receiving treatment in intensive care units can only be achieved through assessments and taking necessary precautions. This approach aligns with a family-centered care approach and establishes a quality healthcare service infrastructure. This research provides data on patient experiences and the needs of patient relatives.
Association of homoarginine levels with iron sufficiency in patients with cardiovascular diseases
Authors: Zhloba A. A. , Subbotina T. F.
Published: August 2024

Background. Sufficiently high levels of homoarginine (hArg) in the blood are associated with the lower risk of all-cause mortality. The relationship between the level of hArg and the availability of iron for energy metabolism and oxygen transport has not yet been evaluated. Objective. The aim of the study was to assess the association of known biochemical parameters, including the levels of amino acids, iron, blood hemoglobin, with hArg levels in patients with arterial hypertension (HTN) and other cardiovascular diseases (CVD). Design and methods. The study included 86 cases (33 men and 53 women) aged 60 (46–67) years old without folic acid and vitamin B12 deficiencies out of a total of 105 examined patients with HTN. Along with routine clinical trials, the plasma concentrations of amino acids: citrulline, arginine, serine, methionine (Met), lysine, hArg, and total homocysteine (tHcy) were studied. The feature associations were investigated in the procedure of multiple linear regression analysis. Results. In 30 % of cases, iron deficiency was observed, and the level of hArg was significantly reduced in more than half of the patients. No association of hArg levels with metabolites involved in transmethylation (Met and tHcy) was found. On the contrary, its significant association with iron assessments was found. Correlations of iron levels with the levels of other amino acids were not found. The best delineation of high and low iron levels according to the ROC-analysis corresponds to a hArg value of 1,55 µM (56 % sensitivity and 92 % specificity), which is very close to the 1,61 µM hArg value calculated from the iron reference cutoff (13 µM) in regression model. Conclusions. Iron deficiency to provide energy metabolism often accompanies CVD and is accompanied by a drop in hArg levels below 1,6 μM. Thus, the hArg level becomes important not only for assessing cardiovascular risk, but also as a parameter of the iron level effect on energy metabolism.
Pozarodzinna sukcesja zarządzania w przedsiębiorstwach rodzinnych
Authors: Domanowska Justyna
Published: August 2024

Badania przedstawione w ramach pracy koncentrowały się na pozarodzinnej sukcesji zarządzania. Większość przedsiębiorstw rodzinnych w Polsce, założonych w latach dziewięćdziesiątych, jest w trakcie lub zbliża się do zmiany pokoleniowej.
Proces sukcesji to jeden z trudniejszych etapów przez który przechodzą firmy rodzinne. Odpowiedni wybór sukcesora zwiększa prawdopodobieństwo przetrwania i rozwoju przedsiębiorstwa. Najczęściej praktykowanym rozwiązaniem jest wybór sukcesora z kręgu rodziny. Jednakże występują sytuacje, gdy takie rozwiązanie jest trudne lub wręcz niemożliwe. Wskazanie pozarodzinnej sukcesji zarządzania, jako dobrej alternatywy dla sukcesji rodzinnej, może mieć duże znaczenie dla dalszego funkcjonowania przedsiębiorstwa rodzinnego na rynku.
Przedmiotem części empirycznej uczyniono analizę czynników wpływających na decyzję o przekazaniu zarządzania osobie z zewnątrz, niezwiązanej z rodziną oraz czynników decydujących o pozostawieniu przedsiębiorstwa w rękach rodziny pomimo przekazania zarządzania przedsiębiorstwem menedżerowi zewnętrznemu.
Dynamic Analysis of Physiological and Biochemical Substances in Two Types of Root Type Alfalfa during Overwintering Period
Authors: Guo Yue , Shi Fengling
Published: August 2024

Background: Cold resistance in alfalfa (Medicago sativa L.) is significantly influenced by root system type. The root system plays a crucial role in water absorption and soil stress response. This study investigates the physiological and biochemical responses of creeping-rooted and taprooted alfalfa to cold stress during early winter and mid-winter periods. Methods: Samples were collected on November 3,2023 and January 7,2024, from the experimental plot. Roots at a depth of 20 cm were cleaned with distilled water and stored in cryopreservation tubes at ultra-low temperatures. Free proline, soluble sugars, soluble proteins, malondialdehyde (MDA), superoxide dismutase (SOD) activity and catalase (CAT) activity were measured using standard biochemical methods. Result: Results indicated that with decreasing temperatures, the contents of soluble sugars, soluble proteins, free proline, MDA and CAT activity increased, whereas SOD activity decreased. In the early overwintering stage, creeping-rooted alfalfa exhibited higher soluble sugar content and SOD activity compared to taprooted alfalfa. During the overwintering period, creeping-rooted alfalfa maintained higher levels of soluble sugars, soluble proteins, MDA and CAT and SOD activities. Principal component analysis identified CAT, MDA, soluble sugars and soluble proteins as key indicators for evaluating cold resistance in alfalfa.
Políticas de investigación en ciencia y tecnología en ámbitos educativos. Referentes internacionales. Periodo 2013-2023
Authors: Gómez Velasco Nubia Yaneth , Ochoa Rodríguez Yon Jairo , Sánchez García Santos Morena , Manrique Rodríguez Ángela María
Published: August 2024

Objetivo: el objetivo de este estudio es examinar las políticas y tensiones entre la OCDE y la UNESCO en los últimos diez años, enfocándose en su incidencia en las instituciones de educación superior.
Originalidad/aporte: radica en la influencia notable que estos organismos tienen en las políticas universitarias a través de directrices específicas, en la importancia de los recursos asignados a la investigación en ciencia y tecnología en el ámbito educativo y, a su vez, en la escasez de tales recursos.
Método / Estrategias/recolección de información: se adoptó un enfoque metodológico mixto, combinando investigación cuantitativa y cualitativa. Se utilizaron la revisión documental y el análisis de indicadores de ciencia y tecnología como estrategias principales para recoger y analizar datos. A través de este enfoque se pudieron identificar y evaluar las tendencias y discrepancias en las políticas de investigación de ambos organismos.
Conclusión: los resultados destacan una tendencia de uniformidad en las políticas de la OCDE en ciencia, tecnología e innovación (CTeI), que a menudo ignoran los contextos específicos y las brechas de inversión y capital humano en diferentes regiones. Por otro lado, se identifican tensiones con la UNESCO en áreas claves como las prioridades de investigación, la equidad en el acceso abierto y la ética y responsabilidad social. En conclusión, el estudio presenta recomendaciones para fortalecer la investigación e innovación en las universidades, enfatizando la necesidad de considerar los contextos locales y fomentar políticas más inclusivas y equitativas. Este estudio contribuye a la comprensión de las políticas universitarias y sirve como referencia para futuras investigaciones en el ámbito de las políticas de investigación institucionales.
Postprandial Hypotension in Elderly Patients: Pathophysiology, Diagnosis and Prevention Measures
Authors: Antropova O. N. , Efremushkina A. A.
Published: August 2024

Postprandial hypotension (PPH) is an important but underrecognized condition resulting from an inadequate compensatory cardiovascular response to meal-induced visceral blood pooling. PPG is recognized as an important clinical problem because it has a high prevalence in the older age group and is associated with the development of cardiovascular complications and geriatric syndromes. Possible pathophysiological mechanisms of PPG: increased visceral blood flow; weakening of baroreflex function due to disorders associated with age or autonomic dysfunction; inappropriate activation of sympathetic nerves; dysregulation of vasoactive intestinal peptides; insulin-mediated vasodilation. Ask about symptoms of postprandial hypotension and a decrease in systolic blood pressure (BP) of ≥20 mm Hg. Art. 15-60 minutes after eating is of paramount importance for making a diagnosis of PPG. One of the main strategies for preventing PPG is to reduce gastric distension (small meals and more frequent meals), resting on your back after eating, and drinking enough water. Walking after eating also appears to help restore blood pressure after eating. Caution should be exercised when prescribing protein supplements in the elderly, modifying the diet by replacing high-nutrient sweeteners with low-calorie sweeteners (d-xylose, xylitol, erythritol, maltose, maltodextrin, and tagatose). Metformin or acarbose modulates the cardiovascular response in patients with diabetes mellitus and reduces postprandial hypotension. Thus, PPG is a fairly common and clinically significant phenomenon in elderly patients. Increasing the awareness of doctors about pathophysiology and methods of diagnosis and prevention will improve the efficiency and safety of managing geriatric patients.
Endopedon pada Tanah yang Berkembang dari Batuan Ultrabasa di Desa Kiram Kecamatan Karang Intan Kabupaten Banjar
Authors: Zakly Muhammad Abiyyu , Syaifuddin Syaifuddin , Haris Abdul
Published: August 2024

Endopedon identification is very necessary to determine the development, physical and chemical properties of soil. The development of endopedons originating from ultramafic rocks around Kiram Village, Karang Intan District, Banjar Regency has not been studied much, therefore it is necessary to explore more about the results of soil development. This research was a descriptive method to identify diagnostic horizons that develop in the endopedon. South Kalimantan is one of the areas where ultrabasic rocks are distributed and is an area with a wet tropical climate. The weathering force of the parent material will be faster in the wet tropics. Ultrabasic rocks in each region have different mineral and chemical compositions. Based on the research results, the Oxic horizon in Profile-1 was found at a depth of 29 cm to 76 cm from the ground surface. While in Profile-2 the Oxic horizon was found at a depth of 19 cm to 110 cm from the ground surface. The formation of the oxic horizon is due to the Latosolization process. Such as the long laterization process is supported by environmental conditions, climate, and rainfall making this laterization process will be better.
Pengaruh Pupuk Cair terhadap pH, Fe-larut, dan C-organik di Tanah Sulfat Masam Desa Danda Jaya
Authors: Faridatus Arifa Mei Latifika , Razie Fakhrur , Syaifuddin Syaifuddin
Published: August 2024

One of the challenges of acid sulfate soil is the high Fe content in the soil, thus effective processing is needed to address its toxicity. The purpose of this study was to determine the changes in soil pH, Fe solubility, and organic-C from liquid fertilizer in acid sulfate soil in Danda Jaya Village, as well as to determine the relationship between soluble Fe and soil pH, organic-C and soil pH, and soluble-Fe. This research was structured using a descriptive method by comparing the application of liquid fertilizer with a control. The study was conducted in the Chemistry, Physics, and Biology Laboratory of the Soil Department, Faculty of Agriculture, Lambung Mangkurat University. The results of the study showed that the application of liquid fertilizer was able to increase pH and organic-C and decrease Fe solubility. Additionally, there was a correlation between soluble-Fe and pH with a coefficient of -0,95, a correlation between organic-C and pH with a coefficient of 0,91, and a correlation between organic-C and soluble-Fe with a coefficient of -0.89. Furthermore, the equation for the relationships was soil pH = -0.002 soluble-Fe + 5.958, Soil pH = 0.30 organic-C + 4,43, and soluble Fe = -154.92 organic-C + 830.15.
Karakteristik Fisika dan Kimia pada Tanah Ultisol di Lahan Perkebunan Karet di Desa Gunung Kupang Provinsi Kalimantan Selatan
Authors: Syahputera Aulia , Haris Abdul , ㅤ Ratna
Published: August 2024

Soil properties are the inherent characteristics of soil bodies in different locations that are influenced by factors such as mineral composition, structure, texture, and organic content. Soil has characteristics that affect the growth of the plants that are cultivated. This study aims to determine the physical and chemical characteristics of Ultisol soil at a depth of 0-50 cm on rubber plantation land in Cempaka District, Banjarbaru City. This research was conducted in the laboratory of ULM Soil Department. The land used was in Gunung Kupang, Cempaka Village, Cempaka District, Banjarbaru City, South Kalimantan Province. The research method used in this study is an exploratory descriptive method whose implementation is carried out directly at the research site and continued with soil sampling as material for analysis in the laboratory. Soil sampling was purposefully determined in 10 minipits in rubber plantations with two sides of observation at five depths, namely 0-10 cm, 10-20 cm, 20-30 cm, 30-40 cm, and 40-50 cm. Thus, all observations amounted to 100 samples. The data analysis used is presented in graphical form and analyzed descriptively. The results of this study show that increasing soil depth causes changes in soil physical characteristics. Physical characteristics of soil texture values affect the value of bulk density, particle density,and soil moisture content. The phenomenon of changes in physical characteristics ultimately affects the chemical characteristics of C-organic, soil pH, N-total, P-total and K-total values.
Strengthening the Capacity of BUMDes Astaguna Trihanggo Village in Facing the Industrial Revolution 4.0
Authors: Aji Juhari Sasmito , Pahlevi Reza Widhar , Hayati Kemala
Published: August 2024

The implementation of community service regarding strengthening the capacity of the establishment of Village-Owned Enterprises (BUMDes) Astaguna in facing the Industrial Revolution 4.0 aims to realize information and communication technology in managing BUMDes operations; it is intended to provide BUMDes with a survival strategy for competitors. The renewal effort is motivated by the social behaviour of society, which is dependent on technological developments, marked by the Industrial Revolution, which disrupted multi-fields and had a global impact. The implementation time was held in the Even Semester of 2023 for 30 days from January 1, 2023, to January 30, 2023. Implementing the service begins with planning, activities, and evaluation involving the partner group as the subject and object of service. The conclusion of the service implementation is the impact of increased understanding, which is realized in BUMDes operational activities, which include BUMDes digitalization, which focuses on providing awareness of digital marketing strategies. Then, there is a business plan preparation using the canvas model and SWOT formulation to find BUMDes strategies, then compiling BUMDes governance to be implemented according to the principles of transparency and accountability.
Training on TEKAR (Caramunting flour) Production as Efforts to Enhance Science Literacy
Authors: Zannah Fathul , Purtina Arna , Permadi Ade S
Published: August 2024

PKBM is one of the educational facilities, especially non-formal education, to enhance the knowledge and skills of people studying there. This is done to support the improvement of life skills to enhance living welfare (social and economic), one of which is in the form of scientific literacy skills. This community service activity aims to enhance the scientific literacy skills of students studying at community learning centres or PKBM Harati through training activities in making caramunting flour. The method used in community service starts from the planning stage, activity implementation stage and evaluation. The evaluation was carried out by assessing the literacy skills of the activity participants, namely 20 residents studying PKBM Harati, located in Sampit City, East Kotawaringin, Central Kalimantan, by giving test questions of 10 multiple choice questions and measured quantitatively. The results of the activity show that there has been an increase in the scientific literacy learning outcomes of the activity participants, namely that at the pretest, they got an average score of 35, and at the posttest, they got an average score of 83. These results indicate that the training activities carried out can have a positive impact. Positive because it provides concrete examples regarding the application of scientific literacy skills.
Improving Students' Cognitive Understanding of Natural Selection Topics Through PhET Simulations
Authors: Murtini Iin , Mawartiningsih Lilik , Cintamulya Imas
Published: August 2024

Natural selection is one of the topics of evolution material that is considered difficult for students, so it is necessary to have a practicum to help in understanding this material. Limited laboratory equipment in schools is an obstacle to learning evolution, so learning media are needed to support evolution learning. One of the learning media that can be applied is PhET simulation. PhET simulation supports evolution learning because it provides simulations in the form of processes of how living things experience natural selection mechanisms. This service program aims to describe students' cognitive understanding of the topic of natural selection with the help of the PhET simulation application. This activity is expected to be used as reference material for teachers who conduct practicums with the help of the PhET simulation application. The subjects who participated in this service activity were 30 students in class XII MIPA. The service activities were carried out on June 16–23, 2023, at SMAN 4 Tuban. The service activities carried out include training, discussion, and guidance. Based on the results of the program, it can be seen that the trainees were very enthusiastic about participating in the PhET simulation activities, the use of PhET simulation was easy to apply, and the trainees were easier to understand the material with the help of this application (87% of the time).
Improving The Ability of Vacational High School Teachers To Implement Student-Character Education Based on Local Cultural Wisdom
Authors: Badeni Badeni , Saparahayuningsih Sri , Juarsa Osa
Published: August 2024

This community service project aims to increase the capacity of SMK Negeri 6 Seluma teachers to educate students' moral values/character based on local cultural wisdom. Community service activities were implemented through a mixed approach of lectures, discussions, and workshops such as forum group discussions, demonstrations, role plays, and panel group discussions. The implementation of community service activities carried out using these methods has made changes in the ability level of SMK Negeri 6 Seluma teachers in (1) mastering the concepts/theories of character education (planting approach, cognitive moral development approach, value analysis approach, value clarification approach, action learning approach, and value integrated approach); (2) identifying the moral character values of local cultural wisdom that are aligned with the moral character values in the teaching materials expected to be studied by students and aligned with the core competencies, basic competencies, and criteria in question; (3) analyzing the subject matter, core competencies, basic competencies, values, and panel group discussions for each grade level; (4) analyzing based on core competencies, basic competencies, panel group discussions, and local values cultural wisdom to be taught to students; and (5) compilation.
Fish Farming in Buckets (Budikdamber) as an Effort to Provide Self-Sufficient Food and Alternative Income
Authors: Mutoharoh Mutoharoh , Najihah Naila , Winarsih Winarsih , Ifada Luluk Muhimatul , Adiwijaya Zainal Alim
Published: August 2024

This program was proposed to overcome food problems, limited land for farming and additional income for the society in urban areas.  The aquaponics in the bucket technique is a relevant solution to be implemented nowadays for urban communities faced with the increase in food prices issue on the market, as reported by target partners. Implementing aquaponics also has the potential to be an alternative income as this produces commodities with selling value. The implementation of this program involves PKK RW members in Bangunharjo as potential partners due to their background as housewives with a high need for a variety of food ingredients and a source of additional income for the family. This program was implemented for six months, from April until September 2023, covering the preparation, practice, evaluation, and assessment stages using the Participatory Learning and Action method. The results showed quite satisfactory results, with an average of 2 harvests of plants being carried out by each partner group and a mortality rate of farmed fish of 16% or 45 of 280 catfish fingerlings.