bluuebunny/crossref_metadata_2025 huggingface dataset:
Evolución y estructura psicolingüística de la función poética del lenguaje.
Authors: Gonzales Moreyra Raúl
Published: March 2022

Se utilizó la técnica del “cloze” para explorar la lectura de textos poéticos (fábulas) en 200 niños entre los 7 y 16 años. Los completamientos fueron calificados siguiendo la caracterización de Jakobson y Levin sobre la función poética como equivalencias fonológicas, semánticas y morfosintácticas. Los resultados demuestran el carácter evolutivo de los desempeños de los niños respecto esta función y el paralelismo de su desarrollo con las etapas piagetanas lógico-concreta y lógico-forma.
Tipos de socialización y desesperanza aprendida
Authors: Macassi Sandro
Published: March 2022

Las nociones de alienación, falta de poder y desesperanza aprendida son revisadas. Sesenta obreros de una empresa limeña fueron evaluados en términos del tipo de socialización dominante (SD) y desesperanza aprendida (DA) en sus tres áreas: falta de motivación, falta de control y expectativas de no-control en el futuro. Las escalas SD y DA resultaron consistentes. El análisis de regresión múltiple con las variables grado de división del trabajo, el grado de instrucción y –en migrantes- edad de arribo y permanencia en la capital, evidenció que el único predictor de DA es el grado de instrucción, correlacionándose negativamente. Los resultados se discuten a la luz de la realidad peruana.
Aportación complementaria de las láminas proyectivas al psicodiagnóstico de Rorschach
Authors: Jiménez Gómez Fernando
Published: March 2022

En el presente artículo se describen las Láminas Proyectivas de Rodríguez. Estas fueron elaboradas como complementarias al Psicodiagnóstico de Rorschach. Se señalan sus características principales, así como los aportes diagnósticos de las láminas, indicándose para cada caso el valor de las mismas para obtener información adicional en lo que se refiere a localizaciones, determinantes, contenidos y factores especiales.
Historia de la psicología aplicada a la educación. ¿se reproducen las contradicciones o la dominación de clases?
Authors: Freitas Campos Regina Helena De
Published: March 2022

En esta investigación se analizan tres aproximaciones diferentes a la interpretación de la historia de la psicología aplicada a la educación. Se presentan y evalúan las contribuciones de la teoría de la reproducción, de la teoría institucional y de la teoría del conflicto de clases para explicar el desarrollo de dos puntos de vista que compiten entre sí sobre la relación entre psicología y educación en Brasil. El artículo concluye afirmando que la teoría de conflicto de clases es el modelo que mejor ayuda a explicar la historia de la psicología educacional en el Brasil.
Human Givens (İnsana Verilen) Terapinin Etkililiği Üzerine Bir Sistematik Derleme Çalışması
Authors: UÇAR Semra
Published: March 2022

Human Givens (İnsana Verilen) Terapi (HGT), bireyin ihtiyaçları doğrultusunda terapi süre-cinin yapılandırıldığı birey odaklı, eklektik ve bütünleştirici tarzı ile kısa süreli bir terapidir. Aynı zamanda, yeni ve kısa süreli yaklaşımlar bağlamında yurtdışında öne çıkan terapi yaklaşımlarından biridir. Bu çalışma ile alan yazında HGT uygulamalarının yer aldığı araş-tırmaları değerlendirmek ve HGT’ye ilişkin bir çerçeve sunmak amaçlanmıştır. Google Aka-demik ve veri tabanları üzerinden “human givens therapy”, human givens approach” ve “human givens” anahtar kelimeleri ile son 10 yıla ait taramalar yapılmıştır. Bu anahtar ke-limelerin geçtiği ve içeriğin ilgili olduğu, psikoloji/psikolojik danışmanlık alanlarında yapı-lan İngilizce veya Türkçe tam metin PDF formatındaki makaleler seçilmiştir. Makaleler içe-rikleri ve makale başlıkları doğrultusunda, 9 makaleye erişilmiştir. Türkiye’de bu yaklaşıma ilişkin çalışmaların olmaması nedeniyle bu araştırma HGT’nin tanıtıldığı ve ele alındığı ilk bilimsel çalışmadır.
Implementasi Pengelolaan Keuangan Masjid Agung Asy Syuhada Pamekasan Berdasarkan PSAK No.45 Tentang Pelaporan Keuangan Organisasi Nirlaba
Authors: Hidayat Moh. Nurul , Priyadi Ira Hasti
Published: March 2022

Masjid merupakan organisasi nirlaba yang harus dan berhak untuk membuat laporan dan melaporkannya kepada para pemakai pihak-pihak yang berkepentingan. Laporan keuangan organisasi nirlaba berbeda dengan laporan keuangan organisasi bisnispada umumnya, salah satu perbedaan utamanya terletak pada bentuk laporan keuangan. Laporan keuangan organisasi nirlaba yang berisi tentang dana atau sumbangan dari berbagai pihak yang harus dipertanggungjawabkan oleh manajemen kepada pihak internal dan pihak eksternal. Penyajian laporan keuangan yang memadai dan sesuai dengan standart yang berlaku umum di Indonesia, yaitu PSAK No. 45 tentang Pelaporan Keuangan Organisasi Nirlaba. Standart yang dibuat untuk memberikan kesetaraan penyajian laporan keuangan organisasi nirlaba dengan tujuan agar mudah dipahami, memiliki relevansi, dapat dipertanggungjawabkan dan memiliki daya banding yang tinggi dalam jangka panjang. Pendekatan yang digunakan adalah metode kualitatif yaitu pengamatan, wawancara atau penelaahan dokumen. Dalam penelitian ini peneliti terjun langsung ke lapangan untuk mendapatkan data-data yang dibutuhkan sesuai dengan tujuan yang diinginkan serta menjalin hubungan baik antara peneliti dan informan yakni Pengurus Masjid Agung Asy-Syuhada Pamekasan untuk mengetahui perihal akuntabilitas pengelolaan keuangan Yayasan Panti Asuhan Bina Umat Al-Mu’thi. Hasil dari penelitian ini yaitu dengan tersedianya laporan keuangan yang sesuai dengan PSAK No. 45 Masjid Agung Asy-Syuhada memiliki informasi keuangan yang akuntabel untuk disajikan pada masyarakat.
Skin Whitening and Anti-wrinkle Effects of Chambirum (Amaranthus mangostanus)
Authors: Kim In Hae , Lee Jae Hwa
Published: March 2022

Purpose: To investigate the cosmetic effects of a chambirum (Amaranthus mangostamus) extract on the skincare by measuring the extract’s antioxidant, anti-wrinkle, and whitening.Methods: To confirm the antioxidant effect of chambirum, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity and superoxide dismutase (SOD)-like activity was determined. To confirm whitening effect of chambirum, tyrosinase inhibitory activity and melanin content were investigated. To confirm anti-wrinkle effect of chambirum, the elastase inhibition effect and type I procollagen production was assayed. B16F10 mouse melanoma cells and CCD986sk human dermal fibroblast cells were used to assay cell viability.Results: The DPPH radical scavenging activity of Amaranthus mangostanus ethanol extracts (AME) and Amaranthus mangostanus water extracts (AMW) was 49% and 56%, respectively, at 500 μg/mL. The SOD-like activity of AME and AMW was 67% and 57%, respectively, compared with that of the standard sample L-ascorbic acid at 38% at 1 mM. AME showed 25.9% (L-tyrosine) and 17.8% (L-DOPA), and AMW showed 23.4% (L-tyrosine) and 18.5% (L-DOPA) of tyrosinase inhibition assay. In addition, the intracellular melanin production in B16F10 mouse melanoma cells was decreased by AME and AMW by 25.5% and 24.0%, respectively. Additionally, the elastase inhibition assay results demonstrated inhibition by AME (19.7%) and AMW (17.2%) at 500 μg/mL and the amount of type I procollagen was shown to be insignificant. Furthermore, B16F10 mouse melanoma cells were 76% and 86% showed a viability 76% and 86% when treated with 100 μg/mL AME and AMW, respectively. CCD986sk fibroblast cells showed a viability 94.5% and 83.6% when we treated with 100 μg/mL AME and AMW, respectively.Conclusion: These results suggest that the chambirum (Amaranthus mangostamus) extract has excellent anti-oxidants, anti-wrinkle, and whitening effects. Therefore, it may have a significant industrial value as a functional material for cosmetic or anti-aging related bioproducts.
PEMBERDAYAAN EKONOMI MASYARAKAT DI PONDOK PESANTREN DALWA BERDASARKAN MODEL EVALUASI SUMATIF CIPP
Authors: Laili Yunita Nur , Zaki Irham
Published: March 2022

Pondok pesantren is an institution that can contribute to empowering the community's economy through its business units. The effort was apparently carried out by Pondok Pesantren DALWA. This institute has 14 businesses, but not all of them have professional management, there are a hotel, mart, tour and travel, bread, and fried chicken. This research uses a summative evaluation model. It has four components are context, input, process, product. This model will report the reason, implementation, and result of empowerment. The purpose of this research was to analyze the model of community economic empowerment in the league. The research method is qualitative. Data collected through observations, interviews and documents. The data is validated by the triangulation of sources and techniques. The result showed the reason for empowerment because of independence, reliance, and da’wah. The program gives priority to male are competent, sincere, and amanah. This program consists of awareness, capacity, and making efficient use based on Islam. It is very useful for individual ability, effort, environment, and league. All of these empowerment cause positive impact to pesantren and societyKeywords: Summative evaluation model, the community economic empowerment, Pondok pesantren Darullughah Wadda’wah
The Utilization of Coconut Coir as Supplementary Feed for Beef Cattle Production
Authors: Nuswantara Limbang Kustiawan , Sunarso Sunarso , Arifin Mukh , Setiadi Agus
Published: March 2022

High feed price is a major problem in the production of beef cattle. Therefore, this study aims to determine coconut coir's technical and economic potential for beef cattle feed. This is an in vivo and in vitro study that involved 95 days trial period and 16 male Brahman crossbreed cattle weighing 134±12.1 kg. The coconut coir was fermented using buffalo rumen liquid and was termed fermented coconut coir (FCC). A randomized block design was used in this research, including four feed treatments, namely complete feed D1 using 15% FCC, D2 using 20% FCC, D3 using 25% FCC and D4 using 30% FCC. The parameters observed were technical performance (protein, dry and organic matter intake), ruminal fermentability, purine derivatives and economic performance. The data were analyzed using analysis of variance and Duncan's multiple range test for posthoc multiple comparisons. The results showed that the intake of beef cattle feed D1, D2 and D3 was higher than D4. Furthermore, the digestibility of D1, D2 and D4 was higher than D3. The purine derivatives of D2 were the highest but not significantly different (P > 0.05) from D1 and D4. In addition, the ruminal fermentability was not significantly different (P > 0.05) among treatments. Moreover, the beef cattle feed on D2 had the best economic performance. The performance results showed that ruminal fermentability, purine derivatives and economic performance of D2 (20% FCC) gave the best results but were not statistically different (P > 0.05) from other variables. Conclusively, coconut coir can be used as beef cattle feed without causing health problems.
Agricultural Land Evaluation Using GIS-Based Matching Method in Highland Areas for Oil Palm Cultivation
Authors: Rendana Muhammad , Rahim Sahibin Abdul , Idris Wan Mohd Razi , Rahman Zulfahmi Ali , Lihan Tukimat
Published: March 2022

Oil palm (Elaeis guineensis) is one of the commodity crops and is mostly found in tropical lands. This study aimed to analyze the current and potential land suitability for oil palm using the geographic information system (GIS) technique. The study was conducted in the Ranau District, Sabah State, Malaysia. Field activity was carried out to collect soil samples and land information in the study area. Land suitability was then assessed using the matching method and GIS software was employed to produce a land suitability map for oil palm. The results indicated that the current land suitability classes in the study area were highly suitable (S1) with a total area of 99,118 ha (27.4%); moderately suitable (S2) with 110,108 ha (30.4%); marginally suitable (S3) with 109,533 ha (30.2%); currently not suitable (N1) with 2,728 ha (0.7%) and permanently not suitable (N2) with 40,693 ha (11.3%). Meanwhile, the potential land suitability classes showed 198,206 ha (54.7%) for S1; 123,281 ha (34%) for S2 and 40,693 ha (11.3%) for N2. Suitable areas that could be planted with oil palm included the gently sloping flank and the low gradient slope margin. Availability of nutrients and work capability were the dominant limiting factors in the study area. The outputs of this study recommend that the Ranau District has the potential for oil palm although it still needs land improvements for sustainable oil palm cultivation.
Performance enhancement of direct torque control induction motor drive using space vector modulation strategy
Authors: Moussaoui L.
Published: March 2022

Purpose. The main objective of this work is to demonstrate the advantages brought by the use of space vector modulation technique in the direct torque control of the induction motor. To achieve this purpose, two different direct torque control approaches (with space vector modulation) are proposed and studied from a comparative aspect with each other and with the conventional direct torque control. The novelty of this work consists in the employment of an Integral-Proportional (IP) speed controller in the two proposed direct torque control approaches and a more in-depth evaluation for their performance mainly the switching frequency of inverter semiconductor components and motor torque ripples. Methods. Two different direct torque control approaches that use the space vector modulation strategy and/or fuzzy-logic control, are described in detail and simulated with IP speed controller. The simulation experiments are carried out using Matlab/Simulink software and/or fuzzy-logic tools. Results. Practical value. Comparison results show that the two proposed direct torque control structures (with space vector modulation) exhibit a large reduction in torque ripples and can also avoid random variation problem of switching frequency (over a wide range of speed or torque control). On the other hand, the use of IP speed regulator ensured good dynamic performance for the drive system as well as considerably minimized peak overshoot in the speed response. Practically all of these benefits are achieved while retaining the simplicity and the best dynamic characteristics of the classical direct torque control, especially with the modified direct torque control approach in which the design or implementation requires minimal computational effort.
Pengukuran Topografi Untuk Pembangunan Penampungan Air Bersih (Studi Kasus: Daerah Rajamandala, Kabupaten Bandung Barat)
Authors: Fauzan Mochammad Rizky Miftah , Jupri Jupri , Ridwana Riki
Published: March 2022

Abstrak: Peta merupakan gambaran kecil atau miniatur kenampakan dari suatu permukaan bumi yang direpresentasikan dalam bidang datar yang meliputi kenampakan alamiah maupun buatan manusia dan memiliki ukuran yang disebut skala. Saat ini perkembangan pembangunan semakin pesat, kebutuhan peta semakin meningkat. Peta sangat penting untuk perencanaan suatu pembangunan. Belum terpetakanya sumber mata air di Rajamandala membuat pengelolaan sumber mata air di kawasan tersebut tidak efektif. Agar pengelolaanya efektif dan efisien dibutuhkan peta topografi di kawasan sumber mata air untuk digunakan sebagai rencana pembangunan penampungan sumber mata air. Peta topografi merupakan peta yang menampilkan gambaran permukaan bumi baik alamiah maupun buatan manusia dan unsur relief disajikan dalam bentuk garis kontur. Pengambilan data dalam pengukuran topografi ini menggunakan metode pengukuran terestris yang dilakukan langsung dilapangan dengan alat seperti ETS, meteran, GPS, prisma, statif, dan jalon. Pengukuran BM dilakukan dengan menggunakan GPS Handheld Trimble. Terdapat dua BM yang menjadi titik referensi pemetaan. Hasil dari pengukuran ini yaitu peta topografi skala 1: 500 yang pemanfaatnya digunakan untuk rencana pembangunan penampungan sumber mata air di Rajamandala.

Kata kunci: Peta Topografi, Pengukuran Topografi, Sumber Mata Air

Abstract: Map is a small picture or miniature of the appearance of a surface of the earth that is represented in a flat area that includes both natural and man-made, and has a measure called scale. Nowadays, current development of developmental is growing rapidly, the needs for map used are increased. Maps are a crucial things for planning a development. With the uncharted springs in Rajamandala making the management of the springs in the area ineffective. In order to be effective and efficient management, a topographic map in the spring area is needed to be used as a plan for the establishment of a spring source. Topographic map is a map that displays a picture of the earth's surface both natural and man-made and relief elements are presented in the form of contour lines. Data collection in this topographic measurement is using terrestrial measurement methods carried  out directly in the field with tools such as ETS, meter, GPS, prism, stative, and jalon.BM measurements are carried out using Trimble GPS Handhelds. There are two BMs that become the reference point for mapping. The results of this measurement are a 1: 500 scale topographic map, the use of which is used for the construction of a spring water reservoir in Rajamandala.

 Keywords: topographical map, topographical measurement, water source (springs
Pemanfaatan Satelit Himawari-8 dengan Metode NWP dan RGB untuk Menganalisis Kondisi Atmosfer Saat Banjir di Sidoarjo Tanggal 28 Mei 2020
Authors: Diniyati Estri , Syofyan Dhiyaul Qalbi , Mulya Aditya
Published: March 2022

Hujan sangat lebat dengan intensitas mencapai 73,6 mm/jam di Kabupaten Sidoarjo tanggal 28 Mei 2020 menyebabkan bencana banjir. Hujan lebat disebabkan oleh adanya aktivitas awan konvektif cumulonimbus. Aktivitas awan ini dapat dianalisis dengan memanfaatkan penginderaan jauh satelit Himawari-8 dengan metode NWP dan RGB yang diolah dengan aplikasi SATAID. Hasil menunjukkan terdapat pola konvergensi dan siklonik di wilayah Jawa Timur yang mengakibatkan potensi pertumbuhan awan konvektif semakin meningkat. Awan mulai terbentuk pada pukul 03.00 UTC dan mulai menutupi wilayah Sidoarjo pada pukul 04.30 UTC. Dengan metode RGB, terpantau awan cumulonimbus yang tinggi dan tebal serta mengandung kristal es. Berdasarkan metode NWP, adanya awan cumulonimbus ini ditandai dengan kondisi atmosfer yang labil dan berpotensi mengalami cuaca buruk dengan nilai SSI -0,1 ℃, CAPE 663 J/kg, CIN 20 J/kg, SWEAT 338 pada pukul 06.00 UTC. Selain itu, berdasarkan data reanalisis Copernicus ECMWF diperoleh nilai divergensi -0,02 s-1  dan nilai kelembapan mencapai >100%. Hal ini menunjukkan bahwa analisis dengan menggunakan metode NWP, metode RGB dan data reanalisis Copernicus ECMWF memiliki kesesuaian dan saling mendukung satu sama lainnya.
Analisis Spasial Kerentanan Banjir dan Longsor di Kabupaten Banyuwangi
Authors: Kurnianto Fahmi Arif , Elfiani Vira , Alfani Ahmad Farhan
Published: March 2022

Banjir dan longsor merupakan bencana yang sering terjadi pada wilayah tropis. Curah hujan yang tinggi dengan disertai material vulkanik muda menjadi pemicu meningkatnya bencana tersebut. Penelitian ini bertujuan untuk menganalisis bencana banjir dan longsor secara spasial. Metode penelitian yang digunakan adalah survei. Data dianalisis dengan pembobotan dan skoring serta dilakukan analisis spasial untuk longsor dengan metode overlay yang meliputi parameter litologi, penggunaan lahan, curah hujan, dan kemiringan lereng. Data dianalisis dengan pembobotan dan skoring serta dilakukan analisis spasial untuk banjir dengan metode overlay yang meliputi parameter litologi, penggunaan lahan, curah hujan, dan jenis tanah.  Hasil menunjukkan bahwa wilayah Banyuwangi memiliki kerentanan tinggi terhadap longsor berada di wilayah dataran tinggi hingga pegunungan dengan litologi didominasi oleh batuan vulkanik muda, sementara banjir mayoritas terjadi di dataran dengan litologi aluvium. Karakteristik batuan vulkanik muda akan menghasilkan tanah vulkanik yang rentan jenuh air, sedangkan aluvium relatif mampu menahan air sehingga memicu banjir.

Floods and landslides are disasters that often occur in tropical regions. High rainfall accompanied by young volcanic materials has triggered the increase in the disaster. This study aims to spatially analyze floods and landslides. The research method used was a survey. Data were analyzed by weighting and scoring and spatial analysis was carried out for landslides with an overlay method which included parameters of lithology, land use, rainfall, and slope. Data were analyzed by weighting and scoring and spatial analysis was carried out for flooding with an overlay method that included parameters of lithology, land use, rainfall, and soil type. The results show that the Banyuwangi region has a high susceptibility to landslides in the highlands to the mountains where the lithology is dominated by young volcanic rocks, while the majority of floods occur in plains with alluvium lithology. Characteristics of young volcanic rocks will produce volcanic soils that are prone to water saturation, while alluvium is relatively able to hold water, triggering flooding.

Keywords: vulnerability, flood, landslide, Banyuwangi, spatial analysis
Perbandingan Klasifikasi Penutup Lahan di Kota Bandung Menggunakan Metode Klasifikasi Berbasis Piksel dan Klasifikasi Berbasis Objek Pada Citra SPOT 7
Authors: Wahyu Ningsih Eka , Sugandi Dede , Somantri Lili , Ridwana Riki
Published: March 2022

Pembangunan akan terus terjadi di suatu wilayah tertentu, sehingga mengakibatkan adanya perubahan penampakan fisik. Fokus utama dalam penelitian ini adalah membandingkan dua metode klasifikasi antara metode klasifikasi berbasis piksel, dan metode klasifikasi berbasis objek dengan menggunakan citra SPOT 7 sebagai data sekunder yang digunakan untuk proses klasifikasi, yang berlokasi di wilayah Kota Bandung. Klasifikasi citra menghasilkan 10 kelas penutup lahan diantaranya, bangunan industri, ladang/tegalan, lahan terbuka, perkebunan, permukaan diperkeras, permukiman, ruang terbuka hijau, sarana olahraga, sawah, dan semak belukar. Hasil klasifikasi dengan kedua metode tersebut akan diuji akurasinya berdasarkan data validasi lapangan, serta dihitung luas penutup lahan dari kedua metode dan nilai akurasi keseluruhannya menggunakan matriks konfusi, yang menghasilkan akurasi klasifikasi citra berbasis piksel sebesar 80% dan akurasi klasifikasi citra berbasis objek sebesar 87%. Berdasarkan hasil akurasi keseluruhan dapat dikatakan bahwa metode berbasis objek lebih baik digunakan untuk klasifikasi penutup lahan di Kota Bandung dibandingkan menggunakan metode klasifikasi berbasis piksel.
Praktik Jual Beli Buah Sistem Karungan Perspektif Kompilasi Hukum Ekonomi Syariah
Authors: Vidiantika Penti , Noviana Lia
Published: March 2022

There are various kinds of buying and selling activities in the Pulung market, starting from providing basic and secondary needs. Including buying and selling fruits with a sack system. In this sale and purchase, the collector does not provide a clear explanation of the quality of the object, so there are often discrepancies. This article aims to answer the following focus issues: First, it is related to how the Sharia Economic Law Compilation reviews the quality of objects in buying and selling fruit with the sack system. Second, it is related to how the Sharia Economic Law Compilation reviews the implementation of compensation in buying and selling fruit with the sack system at Pulung Ponorogo Market. This research includes field research using qualitative methods. While the data collection techniques used were observation, interviews, and documentation. From the results of this study, it can be concluded that the quality of objects in the sale and purchase of fruit with the sack system in the Pulung market, Pulung District, Ponorogo Regency is in accordance with KHES, because Article 76 of the KHES regarding the conditions for objects being traded has been fulfilled. And for the implementation of compensation in the sale and purchase of fruit with a sack system at the Pulung market, Pulung District, Ponorogo Regency, Article 77 of the KHES, because the collectors are already responsible and provide compensation for object defects.

Terdapat berbagai macam kegiatan jual beli di pasar Pulung, mulai dari menyediakan kebutuhan pokok dan sekunder. Termasuk jual beli buah-buahan dengan sistem karungan. Dalam jual beli tersebut pihak pengepul tidak memberikan penjelasan mengenai kualitas objek dengan jelas, sehingga sering terdapat ketidaksesuaian. Artikel ini bertujuan menjawab fokus masalah berikut: Pertama, terkait bagaimana tinjauan Kompilasi Hukum Ekonomi Syariah terhadap kualitas objek dalam jual beli buah dengan sistem karungan. Kedua, terkait bagaimana tinjauan Kompilasi Hukum Ekonomi Syariah terhadap pelaksanaan ganti rugi dalam jual beli buah dengan sistem karungan di Pasar Pulung Ponorogo. Penelitian ini termasuk penelitian lapangan menggunakan metode kualitatif. Sedangkan teknik pengumpulan data yang dilakukan adalah menggunakan observasi, wawancara, dan dokumentasi. Dari hasil penelitian ini dapat disimpulkan bahwa kualitas objek dalam jual beli buah dengan sistem karungan di pasar Pulung Kecamatan Pulung Kabupaten Ponorogo sudah sesuai dengan KHES, karena sudah terpenuhi Pasal 76 KHES mengenai syarat obyek yang diperjualbelikan. Dan untuk pelaksanaan ganti rugi dalam jual beli buah dengan sistem karungan di pasar Pulung Kecamatan Pulung Kabupaten Ponorogo sudah dengan Pasal 77 KHES, karena pengepul sudah bertanggungjawab dan memberikan ganti rugi atas kecacatan obyek.
Penggunaan Aplikasi BuzzBreak Perspektif Hukum Islam
Authors: Lailatul Hanifah Umi , Rofiah Khusniati
Published: March 2022

This research used the BuzzBreak Application in Bungkuk Magetan Village. The purpose of this study is to explain the principles of Islamic law on contracts and the mechanism for using BuzzBreak, then the application of Islamic law on passive income using BuzzBreak in Bungkuk Magetan Village. The qualitative research method was used, with data collection techniques through interviews and documentation. From this research, the key is that the contract and mechanism for the BuzzBreak application in Bungkuk Magetan Village have met the terms and conditions of the ju'ālah contract. It is mainly the official BuzzBreak application from the Google Play Store. The mechanism for using the BuzzBreak application from a website that has implemented it does not meet the requirements. One condition of the ju'ālah contract is that the benefits made by the actor ('āmil) must have a value for their efforts (kulfah), because work that does not have the value of hard work is not worthy of being commercialized according to sharia. Meanwhile, the bonus given to the BuzzBreak application according to the DSN-MUI Fatwa No. 75/DSN-MUI/VII/2009 Regarding Sharia Tiered Direct Selling is not appropriate because there are still bonuses that can be obtained without carrying out the missions in the BuzzBreak application.

Penelitian ini berangkat dari praktik penggunaan Aplikasi BuzzBreak di Desa Bungkuk Magetan. Tujuan penelitian ini untuk menjelaskan tinjauan hukum Islam terhadap akad dan mekanisme penggunaan aplikasi BuzzBreak dan tinjauan hukum Islam terhadap passive income pada penggunaan aplikasi BuzzBreak di Desa Bungkuk Magetan. Metode penelitian yang digunakan adalah metode kualitatif, dengan teknik pengumpulan data melalui wawancara dan dokumentasi. Dari penelitian ini disimpulkan bahwa akad dan mekanisme aplikasi BuzzBreak di Desa Bungkuk Magetan menurut hukum Islam telah memenuhi rukun dan syarat dari akad ju’ālah terutama aplikasi BuzzBreak yang resmi dari Google Play Store, sedangkan untuk mekanisme penggunaan aplikasi BuzzBreak dari website yang sudah dimodifikasi belum memenuhi salah satu syarat dari akad ju’ālah yaitu manfaat yang dikerjakan pelaku (‘āmil) harus ada nilai jerih-payahnya (kulfah), sebab pekerjaan yang tidak ada nilai jerih-payahnya, tidak layak dikomersilkan secara syar’i. Sedangkan pemberian bonus pada aplikasi BuzzBreak menurut Fatwa DSN-MUI No. 75/DSN-MUI/VII/2009 Tentang Penjualan Langsung Berjenjang Syariah belum sesuai karena masih ada bonus yang diperoleh secara pasif tanpa menjalankan misi yang ada di aplikasi BuzzBreak.
Prognostic model including the combination of platelet count and neutrophil–lymphocyte ratio for metastatic renal cell carcinoma treated with sunitinib
Authors: Sato Miki Takenaka , Ida Ayuki , Kanda Yuki , Takano Kaori , Ohbayashi Masayuki , Kohyama Noriko , Morita Jun , Fuji Kohzo , Sasaki Haruaki , Ogawa Yoshio , Kogo Mari
Published: March 2022

BackgroundThe association between the combination of platelet count and neutrophil–lymphocyte ratio (COP-NLR) at the time of adverse events during sunitinib treatment and prognosis is unclear, and prognostic models combining the prognostic factors of sunitinib have not been well studied. To develop a prognostic model that includes the COP-NLR to predict the prognosis of patients with metastatic renal cell carcinoma (mRCC) treated with sunitinib.MethodsWe performed a retrospective cohort study of 102 patients treated with sunitinib for mRCC between 2008 and 2020 in three hospitals associated with Showa University, Japan. The primary outcome was overall survival (OS). The collected data included baseline patient characteristics, adverse events, laboratory values, and COP-NLR scores within the first 6 weeks of sunitinib treatment. Prognostic factors of OS were analyzed using the Cox proportional hazards model. The integer score was derived from the hazard ratio (HR) of these factors and was divided into three groups. The survival curves were visualized using the Kaplan–Meier method and estimated using a log-rank test.ResultsThe median OS was 32.3 months. Multivariate analysis showed that the number of metastatic sites, Memorial Sloan Kettering Cancer Center risk group, number of metastases, hypertension, modified Glasgow Prognostic Score, and 6-week COP-NLR were significantly associated with OS. A higher 6-week COP-NLR was significantly associated with a shorter OS (p < 0.001). The HRs of the five factors for OS were scored (hypertension, mGPS, and 6-week COP-NLR=1 point; number of metastatic sites=2 points; MSKCC risk group=3 points) and patients divided into three groups (≤1, 2–3, and ≥4). The low-risk (≤1) group had significantly longer OS than the high-risk (≥4) group (median OS: 99.0 vs 6.2 months, p < 0.001).ConclusionsThe 6-week COP-NLR, which was associated with OS, was an important prognostic factor in patients with mRCC treated with sunitinib. The developed prognostic model for OS, including the 6-week COP-NLR, will be useful in decision-making to continue sunitinib in the early treatment stage of patients with mRCC.
A case report: CD8 + aggressive cutaneous epidermotropic T cell lymphoma (ACLAE), a rare and ill-defined subtype
Authors: Boujguenna Imane Mohamed , Haouane Mohamed Amine , Marhoume Fatimazahra , Bahbouhi Imane , Rody Kenza Kandri , Hocar Ouafa , Amal Said , Rais Hanane , Belbachir Anass
Published: March 2022

Background: Aggressive" CD8+ cutaneous epidermotropic T-lymphoma is a rare entity belonging to the group of cutaneous lymphomas with a cytotoxic T/NK phenotype and which is characterized by: rapidly evolving tumor lesions at the onset, keratinocyte necrosis, a cytotoxic T immunophenotype and an unfavorable prognosisCase presentation: In this study, we report the case of a A 36-year-old patient with no notable pathological history, presenting a rash made up of plaques evolving for 6 months, associated with scalp lesion and alopecia.Conclusion: LCEA CD8 + is a lymphoma with a poor prognosis, despite the use of aggressive chemotherapy drugs. The use of gemcitabine, pralatrexate, brentuximab, as well as allogeneic stem cell transplantation seems to open up new therapeutic avenues.
Pollution for p romotion： Does senior government leaders'green attention matter？
Authors: Yang Xue , Zhang Peng
Published: March 2022

Does the green attention of senior government leaders reinforce the relationship between environmental performance and local officials’ promotion? To examine the factors that might influence this issue in China, we builds a theoretical linkage between senior government leaders’ green attention and the green governance of officials. Inter-provincial panel data from 2001-2016 were used to examine how the green attention of senior government officials alters political incentives and influences the environmental governance behaviour of local officials. We find that the dualistic logic of local governments’ environmental governance lies in the green attention allocation of senior government leaders. When senior government leaders pay more attention to environmental governance, local officials are more likely to be motivated to govern the environment. As the effect of environmental governance in officials’ jurisdictions is significantly improved, their promotion probability increases as well. We also accounts for the degree of attention allocation variables, and the results suggest that greater environmental pollution reduces the prospect of officials’ promotion, but this effect is significantly negative only in years with a high level of attention allocation.
Evaluation of rock mass permeability along a borehole by integrating the techniques of geological features and logistic regression: A case study in Taiwan
Authors: Hsu Shih-Meng , Liao Yi-Fan , Dong Ming-Chia
Published: March 2022

When the budget for in-situ hydraulic tests is constrained, cost-effective approaches for determining the variations in hydraulic conductivity along a borehole remain enticing for helping design and planning of groundwater-related engineering systems. This study proposes a practical method with probabilistic outputs for fulfilling engineering concerns. First, 474 sets of hydrogeological investigation and hydraulic test data of fractured rock masses in most of the watersheds of mountainous areas of Taiwan were collected. Then, seven geological indices (rock quality design (RQD), depth index (DI), gouge content design (GCD), lithology permeability index (LPI), fracture density (FD), fracture width (FW), and groundwater velocity (GV)) significantly correlated with rock mass permeability were identified. Third, using logistic regression analysis, the seven indices were used as explanatory variables, and the hydraulic conductivity was utilized as an outcome variable (its threshold value is 1 × 10− 6 m/s) for developing prediction models of high groundwater potential zones along a borehole. All indices passed the multicollinearity test, indicating no collinearity between the indices. To make the prediction models proposed more flexible in practical applications, a total of 127 combinations based on the combination selection of seven explanatory variables were explored to develop various prediction models. Through the validation of the Hosmer-Lemeshow test, Omnibus test, and Wald test for all developed models, only 77 models were statistically significant. The 77 models were evaluated by three measures of Nagelkerke R2, SR (success rate), and AUC (area under the curve) to further understand the prediction performance of each model. The results show that the accuracy of the prediction model is positively correlated with the number of geological indices used. When all seven geological indices are used, Nagelkerke R2, SR, and AUC can reach the best values, which are 0.83, 91.6%, and 0.976, respectively. In conclusion, the prediction model developed by combining geological indices with logistic regression analysis can provide a more efficient way of understanding the hydrogeological conditions of a borehole site.
FBXL17/Spastin Axis As A Novel Therapeutic Target of Hereditary Spastic Paraplegia
Authors: Kang Hyun Mi , Kim Mijin , Min Yoohong , Jeong Bohyeon , Noh Kyung Hee , Lee Da Yong , Cho Hyun-Soo , Kim Dae Hun , Kim Nam-Soon , Jung Cho-Rok , Lim Jung Hwa
Published: March 2022

Background Spastin significantly influences microtubule regulation in neurons and is implicated in the pathogenesis of hereditary spastic paraplegia (HSP). However, post-translational regulation of the spastin protein remains nebulous. The association between E3 ubiquitin ligase and spastin provides a potential therapeutic strategy. ResultsAs evidenced by protein chip analysis, FBXL17 inversely correlated with SPAST-M1 at the protein level in vitro and, also in vivo during embryonic developmental stage. SPAST-M1 protein interacted with FBXL17 specifically via the BTB domain at the N-terminus of SPAST-M1. The SCFFBXL17 E3 ubiquitin ligase complex degraded SPAST-M1 protein in the nuclear fraction in a proteasome-dependent manner. SPAST phosphorylation occurred only in the cytoplasmic fraction and was involved in poly-ubiquitination. Inhibition of SCFFBXL17 E3 ubiquitin ligase by small chemical and siRNA-FBXL17 decreased proteasome-dependent degradation of SPAST-M1 and induced axonal extension. The Y52C SPAST mutant, harboring abnormality in BTB domain could not interact with FBXL17, thereby escaping protein regulation by the SCFFBXL17 E3 ubiquitin ligase complex, resulting in loss of functionality with aberrant quantity. Although this mutant showed shortening of axonal outgrowth, low rate proliferation, and poor differentiation capacity in a 3D model, this phenotype was rescued by inhibiting SCFFBXL17 E3 ubiquitin ligase. ConclusionsWe discovered that a novel pathway, FBXL17-SPAST was involved in pathogenicity of HSP by the loss of function and the quantitative regulation. This result suggested that targeting FBXL17 could provide new insight into HSP therapeutics.
Phylogenetic study of Enterobius vermicularis isolates from Northwest of Iran
Authors: Shilanabadi Kaveh Figh , Derakhshan Fatemeh Khadivi , Raeghi Saber
Published: March 2022

Human infection with Enterobius vermicularis occurs worldwide, particularly in children. The Role of E. vermicularis in appendicitis is proven. was aimed at characterization and genotyping f this parasite from different samples inferred by mitochondrial DNA to get the parasitic gene flow among diverse populations. There were 40 appendectomies for acute clinical appendicitis, 40 positive scotch tape samples, and an adult female worm isolated from Urmia and Maragheh in the northwest of Iran. Genetic differentiation, haplotype network analysis, and isolates' population structure were analyzed based on cytochrome C oxidase subunit 1 (cox1) gene. It has been demonstrated that all isolations in the appendectomies specimens are similar, and the genetic difference divergence is seen in adult worm specimens. The neutral indices of the samples of Azerbaijan did not show a significant difference and show that there is no intraspecific and population distribution diversity. Our samples show different haplotypes in the B type of E. vermicularis population and add new information about genotyping of these parasites in Iran. In comparison with other studies, intraspecific variation of this parasite from Iran was observed.
RSEA-Net: Residual Squeeze and Excitation Attention Network for Medical Image Segmentation
Authors: Liang Shufen , Wang Tian , Chen Chen , Liu Huilin , Qin Chuanbo , Feng Yue
Published: March 2022

Background
In recent years, convolutional neural networks have been prominent in medicine image processing, but single convolution and frequent pooling operations very easily produce redundant information or miss key information. This paper designs a residual squeeze and excitation attention network (RSEA-Net) to solve the above problems.
Methods
The network has the following main advantages: (1) It can capture richer and more detailed features at different scales in our proposed step convolution module (SCM), which adopts a parallel structure design and has receptive fields of different sizes. (2) This paper also designs a residual squeeze and excitation attention module (RSEAM), which can improve the useful feature gain through space and channel. It can not only eliminate some redundant information but also improve the overall robustness of the model.
Results
This paper verifies the performance of the RSEA-Net in 2D lung CT and tongue image databases. This paper selects seven models for comparison. The experimental results showed that: The RSEA-Net has multi-size respective fields and can eliminate redundant information. In the 2D lung CT database, the Accuracy, Jaccard coefficient, and Dice coefficient reach 0.9939, 0.9705, and 0.9850, respectively. In the tongue image database, the Accuracy, Jaccard coefficient, and the Dice coefficient of the RSEA-Net reach 0.9954, 0.9794, and 0.9895, respectively, which are better than those of the other seven models.
Conclusion
We propose a new deep network model (RSEA-Net). The structure is composed of two U-shaped networks with left and right layers. These are precoding networks and precision segmentation networks. To avoid losing information or producing invalid information caused by frequent convolution and pooling operations, this paper designs an SCM to obtain more multi-scale features. This paper also designed an RSEAM, which can improve the useful feature gain through space and channel, remove some redundant information, and improve the network’s overall robustness. Finally, we also reduced the number of down-sampling operations and simplified the longitudinal complexity. Experimental results show that our method is superior to the original U-Net and other state-of-the-art methods in two different datasets.
Coordinated activation of DNMT3a and TET2 in cancer stem cell-like cells initiates and sustains drug resistance in hepatocellular carcinoma
Authors: Cheng Tao , Zhou Changli , Pang Jiuxia , Tretyakova Natalia , Tse William W. , Liu Yahui , Liu Shujun
Published: March 2022

Background Resistance to targeted therapies represents a major hurdle to successfully treat hepatocellular carcinoma (HCC). While epigenetic abnormalities are critical determinants of HCC relapse and therapeutic resistance, the underlying mechanisms are poorly understood. We aimed to address whether and how dysregulated epigenetic regulators have regulatory and functional communications in establishing and maintaining drug resistance. MethodsHCC resistant cells were characterized by CCK-8, IncuCyte Live-Cell analysis, flow cytometry and wound-healing assays. Target expression was assessed by qPCR and Western blotting. Global and promoter DNA methylation was measured by dotblotting, methylated-DNA immunoprecipitation and enzymatic digestion. Protein interaction, promoter binding and gene mutations of DNMT3a-TET2 was investigated by co-immunoprecipitation, ChIP-qPCR and Sanger sequencing. The regulatory and functional roles of DNMT3a and TET2 were studied by lentivirus infection and puromycin selection. The association of DNMT and TET expression with drug response and survival of HCC patients was assessed by public datasets, spearman correlation coefficients and online tools. Results We identified a coordination of DNMT3a and TET2 as an actionable mechanism of drug resistance in HCC. The faster growth and migration of resistant HCC cells were attributed to DNMT3a and TET2 upregulation followed by increased 5mC and 5hmC production. HCC patients with higher DNMT3a and TET2 had a shorter survival time with less responding to sorafenib therapy than those with lower expression. Cancer stem cell-like cells (CSCs) displayed DNMT3a and TET2 overexpression, which were insensitive to sorafenib. Either genetic or pharmacological suppression of DNMT3a or/and TET2 impaired resistant cell growth and oncosphere formation, and restored sorafenib sensitivity. Mechanistically, DNMT3a did not establish a regulatory circuit with TET2, but formed a complex with TET2 and HDAC2. This complex bound the promoters of oncogenes (i.e., CDK1, CCNA2, RASEF), and upregulated them without involving promoter DNA methylation. In contrast, DNMT3a-TET2 crosstalk silences tumor suppressors (i.e., P15, SOCS2) through a corepressor complex with HDAC2 along with increased DNA methylation in their promoters. Conclusions We demonstrate that DNMT3a and TET2 act coordinately to regulate HCC cell fate in DNA methylation-dependent and -independent manners, representing strong predictors for drug resistance and poor prognosis, and promising therapeutic targets for refractory HCC.
Socio-demographic and morbidity characteristics in people on long-term sick leave
Authors: Oancea Corina , Capraru Simona , Gherman Despina
Published: March 2022

Background. Certifying long-term sick leave along with coordination of the complex rehabilitation programs are important activities of social insurance doctors. They have the role in preventing the loss of work capacity of employees which may lead to leaving the labor market and transition to other social insurance benefits, such as work disability pension.Objectives. Analysis of long term sick leaves (over 183 days) with the identification of risk factors and population groups with low potential for work capacity rehabilitation.Method. We conducted a cross-sectional study between September 2019 and September 2020. The information was collected from the registers of the National Institute of Medical Assessment and Work Capacity Rehabilitation Bucharest and from the EXPMED application. The data were statistically analyzed using the PSPP software. Results. The highest percentage of rehabilitation was achieved in case of traumatic injuries (73.17%), followed by musculoskeletal diseases (70.06%). We noticed lower recovery in case of nervous system diseases (50.56%) and cardiovascular diseases (44.23%). In other pathologies the recovery percentage was 58.37%. People who regained their work capacity were significantly younger than those who turned to other forms of social benefits, disability pension or old-age pension (47.87 ± 8.93 vs. 53.16 ± 8.43).Conclusions. Most of the subjects (72%) regained their work capacity and did not need disability pension. We identified different socio-demographic and morbidity characteristics in people on long term sick leave and target groups that require intensive intervention measures.
Circulation and seasonality of influenza viruses in different transmission zones in Africa from 2013-2019
Authors: Belizaire Marie Roseline Darnycka , N’gattia Anderson Kouabenan , Wassonguema Bibata , Simaleko Marcel Mbeko , Nakoune Emmanuel , Rafaï Clotaire , Lô Baidy , Bolumar Francisco
Published: March 2022

Background: The Influenza Viruses are responsible for more than 5 million of severe cases and 290,000 to 650,000 deaths every year worldwide. Developing countries support 99% of deaths caused by Influenza in children under age of 5. This paper aims to determine the dynamics of influenza viruses in African transmission areas to identify regional seasonality for appropriate decision making and development of regional preparedness and response strategies.Methods: We used data from the FluMart website collected by Influenza national programs for seven periods of transmission (2013-2019). We calculate the weekly proportions of positive influenza cases and follow the trend of the transmission in countries in the Africa continent to determine the seasonality. Results: Over the period, Influenza A(H1N1) pdm 2009, A(H3N2), A(H5N1) viruses, as well as influenza B Victoria and Yamagata lineages identified circulated in the African regions. A(H1N1) pdm 2009 and A(H3N2) were highly circulated in northern and southern Africa. Influenza activity follows an annual and regional variation. In the tropical band, from the easter to the western via the middle, influenza activity is marked by the predominance of A subtypes despite the strong circulation of all B lineages. In the southern and northern Africa, only season has been identified for both regions. In the Eastern, four influenza seasons are differentiated and three for the Western part.Conclusions: The circulating dynamic generates five periods of intense activity during the seasons, so five types of prevention zone. Particularly the tropical band, which is a mixing zone for all influenza viruses, seasons start in the Eastern to end in the Western. Health authorities from countries with same seasons, will need to implement concerted preparedness and control activities.