bluuebunny/crossref_metadata_2025 huggingface dataset:
Estudo do efeito do teor alumina no pó compósito WC-Ni-Al2O3 processado via Moagem de Alta Energia (MAE)
Authors: Valcacer Samara Melo , Silva Mariana Chianca Lúcio da , Medeiros Isaac Péricles Maia de , Gomes Uilame Umbelino
Published: January 2022

RESUMO A MP é constituída de, pelo menos, três etapas: obtenção do pó, conformação e sinterização. Na etapa de obtenção dos pós uma técnica de amplo uso é a Moagem de Alta Energia (MAE) que além de propiciar a quebra das partículas preexistentes, também pode melhorar a dispersão dos componentes. Um material obtido pela técnica é WC-Co, o metal duro, que apesar de ter propriedades interessantes, como por exemplo, alta dureza e resistência à compressão, não consegue manter tais características quando colocado em trabalho em altas temperaturas, como o corte na usinagem. Como alternativa ao sistema compósito WC-Co, estuda-se a substituição do cobalto pelo níquel, entretanto, o compósito WC-Ni apresenta uma baixa dureza quando comparado ao WC-Co. Para minimizar tal efeito, o presente estudo investigou a possibilidade da adição do óxido de alumínio (Al2O3) aos pós de WC e Ni. O estudo estabeleceu a influência da moagem de alta energia (MAE) nas características dos pós compósitos de WC-Ni-Al2O3 com 5 e 10%p de Al2O3. Fez-se moagem de alta energia (400 rpm) em via úmida pelos tempos de 1, 2, 4, 10 e 20h. As amostras foram caracterizadas por: DRX, particulometria a laser e MEV/EDS. Os resultados mostraram-se promissores uma vez que houve redução de até 50% do tamanho mediano de partícula com os tempos estudados, bem como, formação de partículas compósitas.
Caracterização física e mecânica de blocos de concreto com incorporação de areia de resíduo de construção civil
Authors: Scheifer Danielle Melo , Callejas Ivan Julio Apolonio
Published: January 2022

RESUMO Em decorrência dos problemas ambientais gerados pelas disposições inadequadas de resíduos, o presente trabalho busca encontrar uma alternativa para a reciclagem dos resíduos de construção civil (RCC). Entre as aplicações possíveis, o agregado miúdo reciclado do RCC pode ser utilizado como um componente alternativo em substituição total ou parcial à areia artificial nas misturas cimentícias destinadas à produção de blocos de concreto (B). Assim, este trabalho objetiva analisar a viabilidade técnica sob o aspecto físico e mecânico do uso de agregados miúdos reciclados para a confecção de blocos para sistemas de vedação vertical. Utilizou-se o traço de referência 1:19,19 (cimento:agregados, em massa), no qual o agregado miúdo areia artificial foi progressivamente substituído por areia reciclada de RCC. Foram testadas as substituições nos teores de 25, 50 e 100% de substituição de resíduo. As características físicas e mecânicas dos traços de concreto de referência e com substituição foram avaliadas segundo a norma NBR 12118:2013. Por meio do estudo de dosagem, buscou-se identificar o traço que incorporasse a maior quantidade de resíduos na mistura, mantendo o desempenho dentro dos limites estabelecidos pelas normas. O traço com 50% de incorporação foi aquele que apresentou o melhor desempenho, com teor de absorção de água de 14,30% e resistência média a compressão de 4,13MPa. Os Blocos de concreto da família 15x40 (dimensões de 140x190x390mm) produzidos com este teor de incorporação por meio de uso de máquina do tipo vibroprensa, apresentaram resistência à compressão característica de 3,21MPa e teor de absorção de água de 9,89%, sendo classificados como Classe C, sem função estrutural. Desta forma, os agregados miúdos de origem de RCC são viáveis tecnicamente para serem incorporados em matrizes cimentícias para a produção de blocos de concreto, corroborando com a sustentabilidade urbana.
Medida de consistência do concreto pelo abatimento do tronco de cone automatizado: sua validação e potencialidades
Authors: Pereira João Batista , Maciel Geraldo de Freitas
Published: January 2022

RESUMO A partir do desenvolvimento de um aparato mecânico capaz de realizar automaticamente a medida de consistência do concreto pelo tronco de cone (slump test), este trabalho avaliou a capacidade do equipamento em simular o ensaio preconizado por norma. Medidas de consistência utilizando o ensaio padrão (tronco de cone - slump test) e o equipamento desenvolvido foram efetuadas para diferentes composições de concretos convencionais. Os resultados comprovaram a capacidade do equipamento em realizar o slump test, tanto o processo de levantamento do cone quanto a leitura do abatimento (slump), além de possibilitar menores erros experimentais associados ao operador durante o ensaio. Foram também avaliadas as propriedades tensão limite de escoamento e viscosidade plástica dos concretos produzidos, para isso modelos empíricos estabelecidos a partir de medidas reométricas (slump test modificado por meio do reômetro BTREOM), foram aplicados, os quais forneceram resultados compatíveis com os relatados na literatura. Enfatiza-se, porém, a necessidade de uma medida precisa da consistência, de maneira a não comprometer as avaliações reológicas do material, haja vista a elevada dependência (sensibilidade) da tensão limite de escoamento e mais ainda da viscosidade plástica àquela medida. Ademais, o equipamento proposto neste trabalho permitiu uma caracterização mais completa do escoamento durante o ensaio, fornecendo o comportamento temporal da descida do material (uma medida indireta da viscosidade) até o completo abatimento.
Estudos numérico-experimentais de vigas de concreto armado com reforço de fibra de carbono
Authors: Fugiyama Michele Miwa , Forti Nádia Cazarim da Silva , Jacintho Ana Elisabete Paganelli Guimarães de Avila , Pimentel Lia Lorena , Duarte Isabela Oliveira , Santos Jakeline Dutra dos
Published: January 2022

RESUMO Em algumas construções são necessárias intervenções para restabelecer ou aumentar a capacidade de suporte da estrutura antes de atingir um estado limite. Os Polímeros Reforçados com Fibra de Carbono (CFRP) são um dos mais adequados como elemento de reforço estrutural por ser um material de alto desempenho mecânico e elevado módulo de elasticidade, resistência à fadiga e baixo peso específico. Este trabalho teve como objetivo analisar a eficiência de materiais compósitos de Polímeros Reforçados com Fibras de Carbono (CFRP) como reforço estrutural em vigas de concreto armado, por meio de ensaios experimentais e simulação numérica. Nos ensaios, a armadura da viga de concreto foi dimensionada com resistência insuficiente ao cisalhamento. Nas vigas de referência, inicialmente, surgiram fissuras de cisalhamento, e em seguida as vigas romperam-se à flexão. Nas vigas com CRFP, que foram dimensionadas como reforço ao cisalhamento, as vigas não apresentaram fissuras de cisalhamento e romperam à flexão. Não houve acréscimo significativo da carga máxima. Em apenas uma viga houve o descolamento da fibra de carbono em um dos bordos da estrutura, mostrando boa eficiência do adesivo utilizado. As simulações numéricas foram realizadas utilizando o Método dos Elementos Finitos (MEF) no software ANSYS 18.1. Os resultados obtidos no modelo numérico ficaram próximos aos resultados experimentais.
Consideração da deformação permanente de solos ocorridos na região nordeste na análise mecanística-empírica de pavimentos
Authors: Cabral Wendel Silva , Barroso Suelly Helena de Araújo , Silva Samuel de Almeida Torquato e
Published: January 2022

RESUMO Para estabelecer projetos mais eficientes e critérios construtivos adequados na área de pavimentação é indispensável o entendimento do desempenho dos materiais com relação aos métodos de dimensionamentos mecanístico-empírico. Este trabalho analisa as propriedades de Deformação Permanente (DP) e Módulo de Resiliência (MR) de solos utilizados em camadas de pavimentos para análises de diferentes tipos de dimensionamento, mecanístico-empírico e empírico de rodovias brasileiras. O método de ensaio para obtenção da DP foi o triaxial de carga repetidas de múltiplo estágios (RLT), com aplicação de 10.000 ciclos por estágio, e o dimensionamento mecanístico-empírico realizado pelo método MeDiNa, recém divulgado no Brasil, e pelo programa CAP 3D-D, que realiza análises numéricas de tensões e deslocamentos dos pavimentos propostos. Utilizou-se a técnica de Redes Neurais Artificiais (RNA) para o desenvolvimento dos modelos de previsão de DP. Os resultados mostraram que tanto o método de ensaio, quanto as equações de predição tiveram desempenho satisfatório na obtenção do comportamento da DP. Já os dimensionamentos realizados através dos métodos utilizados resultaram em estruturas distintas. Conclui-se que o modelo e a técnica de obtenção utilizada, bem como a metodologia de ensaio possuem grande potencial para caracterizar e modelar a DP de materiais granulares e que o Brasil deve investir cada vez mais no uso de métodos mecanístico-empírico para análise de pavimentos.
Mechanisms and Models of Kidney Tubular Necrosis and Nephron Loss
Authors: Maremonti Francesca , Meyer Claudia , Linkermann Andreas
Published: January 2022

Understanding nephron loss is a primary strategy for preventing CKD progression. Death of renal tubular cells may occur by apoptosis during developmental and regenerative processes. However, during AKI, the transition of AKI to CKD, sepsis-associated AKI, and kidney transplantation ferroptosis and necroptosis, two pathways associated with the loss of plasma membrane integrity, kill renal cells. This necrotic type of cell death is associated with an inflammatory response, which is referred to as necroinflammation. Importantly, the necroinflammatory response to cells that die by necroptosis may be fundamentally different from the tissue response to ferroptosis. Although mechanisms of ferroptosis and necroptosis have recently been investigated in detail, the cell death propagation during tubular necrosis, although described morphologically, remains incompletely understood. Here, we argue that a molecular switch downstream of tubular necrosis determines nephron regeneration versus nephron loss. Unraveling the details of this “switch” must include the inflammatory response to tubular necrosis and regenerative signals potentially controlled by inflammatory cells, including the stimulation of myofibroblasts as the origin of fibrosis. Understanding in detail the molecular switch and the inflammatory responses to tubular necrosis can inform the discussion of therapeutic options.
Anatomical Variations in Chronic Otitis Media Surgery; Comparison of Tomography and Perioperative Findings
Authors: GÜNEBAKAN Çağlar , KUZU Selçuk , KAHVECİ Orhan Kemal , BUCAK Abdulkadir , ULU Şahin
Published: January 2022

Aim: For a correct and adequate chronic otitis media surgery, it is necessary to correctly define the anatomical structures and to know their possible variations, otherwise, an increase in the complication rate is inevitable. This study aims to present the anatomical variations detected both in preoperative computerized tomography scanning and during operation, and complication rates encountered in 308 patients who underwent tympanomastoidectomy due to chronic otitis media in the light of current literature knowledge.
Materials and Methods: In this retrospective study, the files of 308 patients who underwent tympanomastoidectomy due to chronic otitis media in a tertiary clinic between September 2011 and July 2019 were scanned for encountered anatomical variations detected both in preoperative computerized tomography scanning and during operation and complications.
Results: There was Körner septum in 12 (3.8%) cases, dehiscence in the facial nerve tympanic segment in 12 (3.8%) cases, and lateral semicircular canal dehiscence (LSCD) in 4 (1.3%) cases. In 4 (1.3%) cases, it was observed that the dura was located downward and in 6 (1.9%) cases, the sigmoid vein was located anterosuperiorly.
Conclusion: Always being careful in terms of anatomical variations and possible complications during the operation will increase the success of the surgery. Knowing the anatomical variations and complications related to the temporal region is of great importance for clinicians dealing with ear surgery.
Our Experience with Patients That Diagnosed Ischemic Colitis in Colonoscopy
Authors: GÖKBULUT Volkan , KAPLAN Mustafa , DISIBEYAZ Selcuk , KACAR Sabite , SÜMER Hale , GÖKBULUT Püren , TENLİK İlyas , AKSOY Adem
Published: January 2022

Aim: Ischemic colitis (IC) is one of the most common causes of lower gastrointestinal bleeding, especially in patients over 60 years of age. In this study, we investigated the clinical and demographic characteristics of patients with IC detected by colonoscopy.

Material and Method: This study was conducted retrospectively by examining the patient records of patients who underwent colonoscopy for various reasons between January 2014 and December 2017. Patients with IC pre-diagnosis in the colonoscopy reports were included in the study. A total of 130 patients were found, 18 patients were excluded from the study due to lack of data and the study was conducted with 112 patients.

Results: Definitive IC was diagnosed in 56 of 112 patients who had a preliminary diagnosis of colonoscopy (50%). The average age of patients diagnosed with definitive IC was 68, of which 30 were male and 26 were female. It was observed that IC patients applied to the hospital with complaints of abdominal pain, hematochezia, diarrhea and fever. It is observed that ischemic colitis is most frequently affects left colon. In the doppler findings of patients with IC, all mesenteric vessels and aorta were normal in the vast majority of patients (70%). When predisposing factors that may cause IC were examined, hypertension was observed in 59% of patients, coronary artery disease in 59%, diabetes mellitus in 21% and heart failure in 18%. The vast majority of patients improved with medical therapy (89%). Six patients were given surgery for colon resection (11%), 4 of these patients recovered, but two patients became exitus due to the common thromboembolic condition and associated extensive ischemia (4%).

Conclusion: IC is a disease that presents symptoms such as bloody diarrhea and abdominal pain, especially in elderly male patients with predisposing risk factors, frequently seen in the left colon and responds well to medical treatment, and should be considered in every patient with acute diarrhea and abdominal pain.
Effect of telestroke practices on short-term mortality in ischemic stroke patients
Authors: AKÇA Hatice Şeyma , ALGIN Abdullah , ÖZDEMİR Serdar , KOLBAŞ Fatma , YILMAZ Emine , DİLER Yunus , EROĞLU Serkan Emre
Published: January 2022

Objective
This study aimed to evaluate the effect of telestroke practices on patient prognosis and mortality by comparing the data of patients that presented before and during a period when tele-stroke application was in use.
Method
Stroke patients presenting from October, 2018 to October, 2019 for whom WhatsApp was used for telestroke purposes, were evaluated as the telestroke group. The previous year it was a pre-telestroke group. The two groups were compared in terms of factors affecting prognosis and mortality. All statistical analyses were performed using SPSS version 16.0 for Windows.
Results
A total of 727 patients clinically and radiologically confirmed to have ischemic stroke were included in the study. There were 252(34.6%) patients in the pre-telestroke group and 475(65,4%) patients in the telestroke group. Both rtPA and thrombectomy treatment were significantly higher in the telestroke group(p<0.001). In the first 24-hour evaluation, the rate of discharge increased and hospital admission and mortality decreased in the telestroke group(p<0.001). There was no statistically significant difference between the groups in terms of poor prognosis and 30-day mortality(p=0.470 and p=0.625, respectively).
Conclusion
Telestroke practices not only provide access to the relevant clinical branch for early consultation but also facilitate timely treatment thus leading to improvement in prognosis.
Clinicopathologic features and KRAS mutation incidence of gastric carcinomas
Authors: GÜRSOY Didar , SEÇİNTİ İlke Evrim , DOĞAN Esin , TEMİZ Muhyittin
Published: January 2022

Objectives: This study aims to determine the frequency of KRAS mutations in patients with gastric adenocarcinoma (GAC) in Hatay province, and to determine the relationship of this mutation with some pathological and clinical parameters and to guide the diagnosis and treatment planning of patients.
Methods: Formalin-fixed, paraffin-embedded, and histologically confirmed samples were used in the assessment of KRAS mutation. Sections were taken from the archive tissue samples of each case. Real-Time Polymerase Chain Reaction (RT-PCR) system was used to identify mutations of codons 12 and 13 (exon 2) of the RAS gene. Mutations of GLY12ALA (G12A), GLY12ASP (G12D), GLY12ARG (G12R), GLY12CYS (G12C), GLY12SER (G12S), GLY12VAL (G12V), GLY13ASP (G13D) were performed.
Results: The mutation rate of KRAS was 2% and only one substitution, G12D, was detected. In this case, the tumor was located in the small curvature. Since the number of cases with mutations was low, statistical comparison could not be made between KRAS mutation and clinicopathological factors. A significant difference was found between tumor differentiation and WHO-2010 typing and primary tumor stage.
Conclusions: We found the incidence of KRAS mutation to be 2%. We also estimate that the G12D mutation may be associated with GAC site and surgical margin. Although KRAS mutation in GAC alone is not a prognostic or predictive marker, subtype-specific analysis may provide data that may affect the diagnosis, management and treatment of the disease
Guía de consultorios jurídicos
Authors: Gómez Bautista Jorge Alfredo , Marin Abadía Leidy Yobana , Díaz Cardona William , Vallejo Vilaró Valerie Michel , Tavera Moncaleano Diego Thomas , Cardona Villa Germán Arturo , López Cruz Andrés Fernando
Published: January 2022

Esta guía tiene como propósito acompañar al estudiante en el desarrollo de competencias en diversas áreas del derecho, como lo son los métodos alternativos de solución de conflictos, el derecho penal, el derecho civil, el derecho de familia, el derecho laboral y el derecho público. De este modo, se busca brindar las herramientas necesarias que permitan garantizar una atención oportuna, de calidad y eficiente en los diferentes temas que nuestros usuarios puedan llegar a requerir. Es una base y punto de partida para continuar aplicando y desarrollando las competencias que durante todos estos años se han venido formando, mediante el planteamiento de soluciones jurídicas a los asuntos concretos requeridos.
Internally-headed and doubly-headed relatives in Japanese -- How are they related to each other?
Authors: Kitagawa (†) Chisato
Published: January 2022

Grosu & Hoshi (2019:20), in their rejoinder to Kitagawa (2019), propose that apparent violations of island constraints in the so-called internally-headed relative clauses are accounted for by considering them as reduced doubly-headed relative clauses. This paper shows that this claim by Grosu and Hoshi is not empirically sustainable, and further that it misses the discourse function of doubly-headed relative clauses. A discussion of gapless light-headed externally-headed relative clauses is also presented so as to identify how this construction type interrelates with internally-headed relative clauses and doubly-headed relative clauses.
Some Moral and Ethical Problems of Conducting Investigative Actions Involving Representatives of Ethnic Minorities in Criminal Proceedings
Authors: Kuleshov Roman , Foygel Elena
Published: January 2022

The article focuses on ethical problems of ordering and conducting investigation search activities that, due to the dominant type of activity, include a forensic examination of a dead body and exhumation, and involve representatives of some ethnicities and ethnic groups. It is stated that although these investigative actions are in some cases obligatory, the investigation does not always have an opportunity to carry them out due to active counteraction of the deceased person’s relatives connected with the necessity of observing ethnic-religious rites and traditions on preserving and burying the body. The authors analyze the subjective significance of observing moral and ethical norms for the victims and other representatives of the diaspora, explain the position taken by the relatives, outline the consequences of ignoring these ethnic-religious norms. Based on the necessity of resolving a conflict situation, they offer recommendations on overcoming it though specially developed tactical steps.
Elements of the System of Checks and Balances in Operational Search Activities
Authors: Melikhov Alexander
Published: January 2022

The principles of the unity of the system of state power and of the separation of powers should be adequately combined in operational search activities. The functioning of state agencies and organs involved in operational search or similar activities is a vital attribute of the state’s sovereignty. In the existing system of the separation of powers, operational search activity remains an effective inter-agency institute of control over all levels of government with the purpose of ensuring their unity because it is under the control of the President of the Russian Federation through the distribution of powers of the subjects of operational search activities depending on the sphere and area of their work, the regulation of their levels of workforce and resources, as well as the authority to appoint to positions and highest military and special ranks the management of operational search activities.
Obtaining Samples for a Comparative Study: Theoretical, Normative and Law Enforcement Problems
Authors: Zaitseva Elena
Published: January 2022

The article analyzes the debatable aspects of the normative regulation of obtaining samples for a comparative study according to the current Criminal Procedure Code of the Russian Federation. Attention is paid to the key problems in the regulation of this action, and to the difficulties that law enforcement employees face due to them. The author examines the questions of defining the legal nature of obtaining samples for a comparative study, and the possibility of using the operative search potential instead of the procedural method to obtain comparative samples. While analyzing the problems of setting the limits of compulsion for this action, the author stresses the incorrectness of some wording in the law (Art. 202 of the Criminal Procedure Code of the Russian Federation). In the light of ensuring the right of criminally prosecuted persons to defense, the author also presents a critical assessment of the legal positions of the Constitutional Court of the Russian Federation reflected in the Definition of July 23, 2020 № 1856-0, in the part where obtaining samples for a comparative study is recognized as an action of urgent nature.
On the Necessity of Developing a Unified Definition of «Darknet» in Criminalistics
Authors: Protasyevich Aleksander , Skryabikova Yulia
Published: January 2022

The article is devoted to counteracting crimes committed with the use of information-telecommunication technologies, specifically, the Internet. Criminals use the Internet actively to conduct criminal business transactions while hiding in the shadow part of the net — Darknet. This net provides offenders with opportunities for hiding by offering anonymous nets that guarantee a high level of confidentiality. This fact makes it considerably harder for law enforcement bodies to counteract crimes committed with the use of information technologies. Besides, an analysis of the criminal situation in the Russian Federation showed that law enforcement work of counteracting this type of crimes is not effective at the present stage. Due to this, there is a need for improving the level of “digital” literacy of law enforcement employees as well as the development of a criminalistic base that takes into account the digital progress. The authors offer a definition of “Darknet” that describes the essence of this net and that will become the starting point for researching the Darknet phenomenon as an object of criminalistics. The conducted research will make it possible to obtain new sources for building the elements of criminalistic description of crimes and a special criminalistic theory of investigating crimes committed with the use of Darknet.
Investment Appeal of Modern Electric Power Generating Companies
Authors: Sheveleva Galina
Published: January 2022

Nowadays, the conditions for the further reforming of Russian electric power industry and developing its generating companies are changing. However, the problems of attracting investments into this sphere and increasing the investment appeal of the involved companies remain unsolved. The purpose of the research is to assess the investment appeal of the modern wholesale and territorial companies generating electric power, mainly for portfolio investors. The assessment was primarily conducted using the method of financial ratios, taking into consideration the approach used by A. Zaporozhan, A. Petrova and M. Kalvarskaya for assessing investment appeal of generating companies at the initial stage of the reforming of Russian electric power sector. Specific amendments to this approach are suggested. These amendments concern the increase of the number of the assessed objective financial indicators and specification of their content. Componentwise ranking of companies according to their investment appeal was conducted. It allowed the author to identify leaders and outsiders. One can observe comparability of the obtained results with the assessment of the investment appeal of generating companies as far as the quality of their corporate management is concerned, conducted by the center for corporate development ТopCompetence, Association of Independent Directors and National Research University «Higher School of Economics».
Management Efficiency: Necessity and Possibility of Assessing the Process and Result
Authors: Kondratskaya Tatiana , Dmitrienko Evgenii
Published: January 2022

The practice and theory of modern management associates the assessment of efficiency with the results of the company's work or changes in the level of use of individual resources. The criteria are results such as profit, profitability, labor productivity, the level of financial independence and others. We judge about the effectiveness of management by changes in these criteria. The number of criteria varies, and the results often show opposite conclusions about the level of effectiveness. This approach is not relevant in market conditions since the external environment, in which the company operates, remains beyond the assessment zone: with a shrinking market, profit may decrease but this is not evidence of deterioration in management. The second methodological problem is the lack of assessment of the management process itself as a set of certain actions. The purpose of the study was to develop a scientific approach to assessing the effectiveness of management in a competitive environment. The article presents a methodology for assessing efficiency not only in terms of results (management efficiency) but also actions (process efficiency). The research methodology is based on critical analysis and synthesis of theoretical and practical approaches to management assessment. The unity of the assessment of the management process and its results is the scientific novelty of the proposed methodology. The methodology was illustrated by the example of the Irkutsk Oil Company.
Consumer Extremism in the Insurance Market: Problem Statement
Authors: Stepanova Marina
Published: January 2022

Consumer extremism has recently taken the form of a mass phenomenon, gradually penetrating into the insurance industry. Since it negatively affects not only the reputation and financial position of individual insurers, but also the development of the insurance market as a whole, the task of finding ways to counteract the facts of unfair behavior of consumers of services is becoming urgent. It should be borne in mind that consumer extremism is a complex, multifaceted phenomenon: it has legal, and at the same time social, economic, psychological foundations, motives and consequences. Therefore, it is extremely important to go beyond the purely legal aspects in this research. In this regard, the purpose of the work was to identify the most significant aspects in the study of consumer extremism as a phenomenon that takes place in the insurance market. As a result of the study, we came to the conclusion that it is necessary to take into account both the consumer's polysubject connections, which arise in the insurance market, and the multidisciplinary ones, which are formed within a particular insurance transaction. When assessing a possible area of relations where consumer extremism can manifest itself, we should take into account all scenarios of consumer’s activity from the passive one, in which the relationship does not go beyond the «policyholder — insurer», to the proactive one, when representatives of the insurance infrastructure are involved in the relationship. In the result a set of measures has been offered which would help prevent consumer extremism cases while implementing insurance relationships.
Alternative Options for Modernization of Regional Heat Supply Systems: Environmental and Economic Aspects
Authors: Bergen Darya
Published: January 2022

At present, environmental pollution by fuel combustion products is one of the key problems in the heat supply sector. It affects the entire population of the Earth. The purpose of the research is to substantiate the necessity of ecological upgrading of thermal power facilities in the Irkutsk region and using a part of municipal solid waste as an alternative fuel at thermal power facilities of the Russian Federation. The research shows that the use of the two kinds of fuel (solid biofuel and alternative fuel) can reduce the anthropogenic load. This measure can be a way of energy efficient disposal of accumulated and annually generated production and consumer waste. The transition to alternative fuels can be most efficiently implemented in boiler houses. This is due to lower capital investments in the modernization of boiler houses as compared to the modernization of thermal power plants. The calculations in the article confirm that the implementation of environmental modernization of regional heat supply systems is not economically beneficial for entrepreneurs. The state should supplement the methods of regulation with targeted co-financing of programs for the modernization of thermal power facilities in order to accelerate the processes of modernization of heat supply in the Russian Federation. At the same time, the recipients of support must comply with the established indicators further on.
Assessment of the Impact of Industry 4.0 Technologies on the Economic Growth of the Russian Segment of Rail Transportation
Authors: Gulyi Ilia
Published: January 2022

Formation of cyber-physical models in the economy is perceived as an imperative and the objective reality. However, the issues of developing scientific and methodological support for projects aimed at creating digital business models, namely, economic algorithms for their evaluation, are currently unsolved. The purpose of the study is to work out a system of indicators for assessing the impact of industry 4.0 technologies on economic growth, and further verification of the performance. The empirical base for the study is the reporting documents of the largest national carrier — Russian Railways Holding. The research methods include a descriptive diagnostics, statistic data structuring, a correlation analysis of data, a comparative analysis, and others. The results: the author proposes a system of statistic indicators for assessing the impact of industry 4.0 digital technologies on economic growth parameters, and makes an assessment of these indicators in Russian Railways Holding. Conclusion: investing in a digital business model enhances economic growth, increases marginalization via electronic channels and other means of interaction with the consumer, and provides for optimizing operating costs.
Marketplace as a Business Model of E-Commerce
Authors: Kordina Irina , Khlebovich Daria
Published: January 2022

The world market of e-commerce is growing actively due to the development of such format of trade as marketplace. Its business model is only being formed, numerous factors influence its content in contradiction with each other. Its increasing popularity leads not only to new opportunities but also to new obstacles for market players, which can cast a doubt on viability of its use. The purpose of the article is to reveal what strategic decisions taken by developers and managers of marketplaces allow the creation of an effective combination of buyers’ and sellers’ aims on the platform, thus, providing mutually profitable exchange for everyone. Three approaches to the study of marketplaces have been identified based on the analysis of the empirical base consisting of secondary information: as a framework that controls the behavior of buyers and sellers in the electronic environment; as an information system; as a business model of an e-commerce. It is concluded that there are conflicting objectives with which the key participants come to the marketplace. The understanding of the business model of the marketplace can contribute to achieving consistency between the interests of sellers and buyers. Four types of marketplace business models have been identified, and they are classified into groups according to three components: value proposition, forms of revenue generation, content of the value creation process. It has been shown that the business model of a marketplace has both advantages and disadvantages, which forces market players to develop focused strategies, and at the same time marketplaces to create value propositions of at least four types: communication stimulation, business transaction automation, coordination of the market as of an intermediary in the value chain, integration of firms and process optimization. A conclusion was made about the prospects of a business model with competitive advantages created for each marketplace.
Estudio para la calidad y prospectiva de la Planeación Estratégica organizacional en Educación Superior
Authors: Vélez Jiménez Dolores , Aragón Sanabria Roberto , Rodríguez González Michel Segismundo
Published: January 2022

Los cambiantes tiempos del presente siglo, y la contingencia sanitaria mundial, han traídonuevas formas de administración de las organizaciones. En el caso particular de la EducaciónSuperior y de forma precisa, en universidades de corte privado, la operación se ha modificado. Porlo tanto, el objetivo de esta investigación fue elaborar un estudio para la calidad y prospectiva de laPlaneación Estratégica, a partir de la integración de elementos normativos, estratégicos y operativoscon base en aspectos de la estructura y comportamiento organizacional. El cumplimiento delobjetivo permitió elaborar un modelo lineal con alta correlación y así considerar variables de dichoselementos, siendo las más relevantes, las relacionadas con el elemento normativo, o sea, la FilosofíaInstitucional, tanto la Misión como la Visión, las cuales, en sus preceptos, puntualizan la calidada lograr en el servicio institucional, tanto administrativo como preponderantemente educativo.El enfoque metodológico fue cuantitativo, de profundidad correlacional y no experimental. Losinformantes clave se integraron en una muestra del personal administrativo, para lo cual, se aplicóun cuestionario con escala de respuesta, los datos fueron procesados estadísticamente. Se infiereque el trabajo estratégico se implementa con calidad si se integran los procedimientos e indicadoresde medición en cada área administrativa, así como su alta correlación con el cumplimiento de laorganización, el cual a su vez promueve un servicio educativo de calidad.
Afectividad, vulnerabilidad y límites de la razón científica
Authors: Gazmuri Barros Rosario
Published: January 2022

Este trabajo analiza la noción de racionalidad propia de nuestra cultura, marcada por el paradigma científico.Según este, la razón tiene la capacidad de descifrar las leyes inscritas en la realidad de manera ‘clara y distinta’ con el fin de dominar esa misma realidad, y transformar aquello que lee. Esta formulación lleva al no reconocimiento del propio límite del ser humano. El objetivo primero de este trabajo es la comprensión de la razón desde un nuevo paradigma. El segundo, estudiar la conexión de la cuestión de la afectividad con la esencial vulnerabilidad del ser humano y las consecuencias de esto en la acción moral. El escrito está estructurado en cinco apartados. En el primero, se analizará la noción de razón tal como es concebida desde el modelo de las ciencias. El segundo se centrará en las consecuencias que dicha noción ha tenido en nuestra cultura. El tercer apartado estudia la cuestión que engrana todas las demás: la recuperación del valor cognoscitivo de los afectos, para, a partir de esta recuperación replantear, en el cuarto apartado, la cuestión del uso práctico de la razón y la acción moral. Por último, se propone el modelo de la obra de arte como posibilidad de reencuentro con las dimensiones del ser humano silenciadas por la noción cientificista de verdad.
El aprendizaje fuera de lugar como una crítica pragmatista de las ciencias cognitivas
Authors: Saharrea Juan Manuel
Published: January 2022

El vínculo entre ciencias cognitivas y filosofía es fructífero y diverso. Sin embargo, son pocas las tentativas filosóficas que examinan el concepto de aprendizaje en su relación con aplicaciones para el campo educativo. El pragmatismo filosófico ofrece un marco teórico sustentable para efectuar esta tarea. Este estudio se plantea como una aproximación al concepto de aprendizaje desde el pragmatismo contemporáneo de Robert Brandom (1994, 2001). Concretamente, analiza este concepto como una instancia de la idea de ‘prácticas sociales’, a partir de la concepción sobre normatividad que Brandom propone, evaluando las ventajas epistemológicas de esta postura. Al mismo tiempo, advierte las implicancias de reducir el aprendizaje a regularidades causales o naturales, tal como se desprende del abordaje cognitivista en educación. A tal fin, el artículo sitúa las filiaciones de tradición y conceptuales de la idea de ‘prácticas sociales’ en la filosofía reciente, y a partir de dicha reconstrucción muestra que es posible un abordaje del aprendizaje más allá del cognitivismo (sin cuestionar sus contribuciones posibles). Asimismo, señala los vínculos entre aprendizaje y norma, así como también entre aprendizaje y lenguaje. Como resultado, este análisis permite situar el aprendizaje formal en el marco de las prácticas sociales, explicar su naturaleza normativa y definir el tipo de condicionamiento que el lenguaje adquiere en él.
FINANCIAL SUPPORT FOR SOCIALLY ORIENTED NONPROFIT ORGANIZATIONS IN RUSSIAN REGIONS
Authors:   National Research University Higher School of Economics, Philippova Anna
Published: January 2022

Currently, socially oriented nonprofit organizations (SO NPOs) in Russia are actively engaged in the process of social services provision. The support provided to them, including the financial support provided by the regional authorities, is extremely important for SO NPOs. This article describes the reasons why the state involves NPOs in social services provision and gives them support, and the advantages and disadvantages of NPOs in services provision. We analyze the size, structure and dynamics of financial support for nonprofit organizations at the regional level and factors related to the size of support, as well as the criteria for granting subsidies (one of the types of support). The criteria were analyzed based on the regional legislation of 52 regions of Russia. The analysis of the size, structure and dynamics of financial support was conducted on the data from registers of SO NPOs that received support of 43 regions of Russia for 2016-2018. Our analysis demonstrates an increase in the total amount of support and a significant intraregional and interregional differentiation in the size of support. Using the method of ordinary least squares, we found that the average per capita value of financial support provided to the SO NPOs at the regional level is positively associated with per capita regional budget revenues, the share of education expenditures in the total amount of regional budget expenditures and the quality of life in the region.
[RETRACTED] Quantitative Three-dimensional High Definition Microvessel Imaging for characterization breast masses v1
Authors: Gu# Juanjuan
Published: January 2022

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Breast cancer, a major cause of morbidity and mortality in women, is highly dependent on angiogenesis for its growth and distant metastasis. Furthermore, new blood vessels in malignant tumors are structurally abnormal and different from benign. Imaging techniques that provide information regarding tumor microvasculature structures could aid cancer detection. This protocol is to advance the development and evaluate the performance of a quantitative 3D microvessel imaging technique to provide quantitative information of morphological features of tumor microvessel as new biomarker for differentiation of malignant and benign breast masses. Our team has developed a new 2D contrast-free ultrasound (US) microvessel imaging technique based on novel processing procedures for revealing and enhancing submillimeter size tumor microvessels and complemented this technique with novel quantification tools to quantify vessel morphology. The results of quantitative 2D-HDMI for differentiation of malignant and benign breast masses are promising; however, the 2D imaging method overlooks some important 3-dimensional (3D) morphological features, such as the connectivity of the blood microvessels, leading to under- or overestimation of these parameters. Here, we propose to advance the development of a new quantitative 3D High-Definition Microvascular Imaging (q3D-HDMI) to provide complementary diagnostic information to the conventional US. The new technique, q3D-HDMI, uses high frame rate ultrasound imaging and is based on novel processing and quantification procedures for 3D imaging to reveal and quantify microvessel morphology in tumor volume. In this protocol we evaluate the diagnostic performance of q3D-HDMI for characterization of breast masses in a population of pre-biopsy patients; correlate the results with pathology as the gold standard.We also compare q3D-HDMI and q2D-HDMI in differentiating malignant from benign breast lesions
Freely Moving Visuomotor Learning Assay with Reversal Learning v2
Authors: Eleftheriou Constantinos
Published: January 2022

The goal of this protocol is to assess visuomotor learning and motor flexibility in freely-moving mice, using the Visiomode touchscreen platform. It modifies the original protocol's (dx.doi.org/10.17504/protocols.io.bumgnu3w) last stage by replacing forelimb reaching with a reversal learning paradigm
[RETRACTED] Power CBD Gummies UK: Dragons’ Den “Elite Power CBD Gummies UK” 2022 v1
Authors: CBD Gummies UK Reviews Power
Published: January 2022

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Produced using hemp plants, Elite Power CBD Gummies to stop smoking might give numerous different advantages, for example.
Effectiveness of the “Person First – Please” educational intervention for nurses in older people long-term care –protocol for a cluster RCT v1
Authors: Pakkonen Mari , Stolt Minna , Ylönen Minna , Pasanen Miko , Suhonen Riitta
Published: January 2022

Aim. To evaluate effectiveness of “Person First –Please” (PFP) intervention in supporting nurses’ collective competence in Person-centred Care (PCC) in Long-Term Care (LTC) of older people. Design. Cluster randomised controlled trial. Methods. Intervention group comprising nurses working on older people LTC will receive PFP Continuing Education (CE) intervention; control group will work as usual. The primary outcomes are nurses’ individual PCC competence and intervention’s effectiveness for collective competence. Secondary outcomes are PCC climate as perceived by nurses, residents and their families. Measurements are conducted three times (baseline, after PFP intervention and after 6-week follow-up) in both groups. Results. The study will provide evidence of PFP’s effectiveness and its influence on PCC climate of older people LTC. If effective, the educational intervention can be used to improve PCC and quality care for older people. Keywords Person-centred care, older people, long-term care, intervention, continuing education, collective competence
Pilihan Raya di Persekutuan Tanah Melayu, 1948-1959 dan Pengenalan First Past the Post
Authors:   Jabatan Sejarah, Fakulti Sastera & Sains Sosial, Universiti Malaya 50603 Kuala Lumpur. Malaysia, Mohd Rus Ahmad Kamal Ariffin , Mohd Rosli Mohamad Khairul Anuar ,   Independent Researcher, 43500 Semenyih, Selangor Malaysia, Johar Siti Norul Aqillah ,   Jabatan Sejarah, Fakulti Sastera & Sains Sosial, Universiti Malaya  50603 Kuala Lumpur Malaysia
Published: January 2022

Artikel ini membincangkan pengenalan prinsip First Past The Post (FPTP) dalam sistem pilihan raya Persekutuan Tanah Melayu (PTM) antara tahun 1948-1959. FPTP merupakan sistem pemilihan calon yang bertanding dalam sesebuah kawasan pilihan raya dan calon yang memperoleh undian terbesar dikira sebagai pemenang meskipun mereka yang mengundi calon tersebut bukanlah kumpulan yang memperoleh majoriti mutlak. Objektif artikel ini bertujuan mengenal pasti permulaan prinsip FPTP dan sejauh mana ia membantu mewujudkan dominasi Melayu dalam dua pilihan raya umum era 1950-an. Kajian ini menggunakan pendekatan sejarah dengan menggunakan sumber-sumber primer di Arkib Negara yang terdiri daripada Colonial Office, laporan kerajaan dan akhbar. Melalui penelitian ke atas sumber, didapati FPTP secara jelas mula dipraktikkan dalam pilihan raya peringkat negeri tahun 1954. Pelaksanaan prinsip ini di peringkat kawasan pilihan raya dilihat tidak bermasalah kerana sistem tersebut hanya memerlukan seorang calon dengan undi terbesar diisytihar sebagai pemenang. Kemenangan Perikatan dengan keahlian majoriti dalam majlis perundangan bagi pilihan raya 1955 membolehkan rundingan ke arah kemerdekaan mengambil langkah yang lebih serius. Dalam konteks sistem pilihan raya, Suruhanjaya Reid, badan yang bertanggungjawab merangka perlembagaan merdeka, memutuskan bahawa sistem pemilihan yang akan dipraktikkan dalam pilihan raya pasca merdeka adalah berasaskan prinsip FPTP. Suruhanjaya Reid juga mengambil pendekatan memastikan sempadan kawasan pilihan raya mestilah bersandarkan dominasi Melayu. Harapan tersebut jelas tergambar dalam Pilihan Raya Umum 1959 apabila 66 daripada 104 kawasan pilihan raya yang dipertandingkan adalah dominasi Melayu. Kata kunci: First Past The Post; Suruhanjaya Reid; orang Melayu; pilihan raya; Persekutuan Tanah Melayu
Primary Teachers’ Perceived Stress and Indicators of Burnout during COVID-19 Pandemic
Authors: Todor Ioana
Published: January 2022

Studies conducted in various countries indicate that teachers’ exposure to high levels of occupational stress makes them vulnerable to burnout syndrome. There are various sources of occupational stress in teaching profession: teaching overload and bureaucratic tasks, students’ misbehaviors and lack of motivation, overpopulated classes and lack of didactic resources and materials, time pressure, lack of support from the administrative staff and from other more experienced colleagues, lack of adequate professional training, high expectations from the parents and society etc. The Covid-19 pandemic dramatically changed teachers’ professional and personal lives, multiplied and amplified their sources of occupational stress, making them even more vulnerable to burnout. The perceived stress and the indicators of burnout in primary school teachers from Romania during the COVID-19 Pandemic were investigated in this study. The results were discussed in relation with those obtained in similar studies conducted in other countries and cultures.