bluuebunny/crossref_metadata_2025 huggingface dataset:
Factores asociados a la organización de productores en Tierra Blanca, Veracruz
Authors: Dzib-Poot Yazmin Neguibi del Rosario , Carranza-Cerda Ignacio , Estrella-Chulim Néstor Gabriel , Chalate-Molina Hector
Published: December 2021

Objetivo: describir los principales factores culturales, factores sociales (capital social), factores psicosociales (percepción y expectativa de beneficios), factores socioeconómicos y variables asociadas con la producción de maíz que inciden en la participación y grado de organización para actividades agrícolas de los productores reubicados chinantecos y originarios locales del municipio de Tierra Blanca, Veracruz. Metodología: se diseñó una guía de observación, guía de entrevista semiestructurada (informante clave) y cuestionario estructurado que fue aplicado a productores reubicados y originarios. La información se analizó con el IBM SPSS Statistics 19. Resultados: se encontró que el factor cultural es clave para la tendencia a participar en grupos organizados; en el factor social, las normas y sanciones cumplen condiciones determinantes para el grado de organización, asi como, la edad del productor y número de integrantes de la familia; con respecto a la percepción de beneficios la asesoría técnica, acceso a maquinaria y tecnología fueron algunos de los aspectos relevantes que se relacionan con la organización y en la expectativa para participar en grupos destacan la transformación y venta, gestión de apoyos, acceso a maquinaria y tecnología; también se encontró que la producción de maíz está asociada con el grado de organización de los productores. Limitaciones: tiempo, distancia y recursos económicos para analizar los factores organizacionales de otros productores. Conclusiones: entre los dos grupos de productores existen diferencias de participación y grado de organización, lo cual se debe a factores culturales, factores sociales (capital social), factores psicosociales (percepción y expectativa de beneficios), factores socioeconómicos y de producción.
Рукокрылые: общая характеристика отряда : учебное пособие : для студентов, обучающихся по направления подготовки бакалавриата 06.03.01 «Биология», 05.03.06 «Экология и природопользование», специалитета – 30.05.01 «Медицинская биохимия», 30.05.02 «Медицинская биофизика», 36.05.01. «Ветеринария», магистратуры – 06.04.01 «Биология: биологические системы, структура функции технологии», 06.04.01 «Биология: биологическая безопасность»
Authors: Щелканов М.Ю. , Табакаева Т.В. , Любченко Е.Н. , Короткова И.П. , Щелканов Е.М. , Панкратов Д.В. , Дунаева М.Н.
Published: December 2021

Данное пособие направлено на изучение основ биологии рукокрылых (летучих мышей и крыланов). В пособии содержится теоретический материал по основным вопросам происхождения, таксономии, анатомии, физиологии и экологии этого отряда животных. При описании иммунной системы рукокрылых акцент делается на толерантность их организма к вирусным инфекциям, что позволяет рукокрылым выступать в качестве природного резервуара вирусных инфекций, опасных для других потенциальных хозяев. Для улучшения усвоения материала пособие сопровождается таблицами и рисунками, даются контрольные вопросы для самоподготовки и проверки знаний студентов. Предназначено для студентов и аспирантов, специализирующихся в области биологии, биофизики и медицины.
Pengaruh Integrasi Media Komunikasi Terhadap Pengetahuan Pengunjung Wisata Edukasi Pertanian Kabupaten Tulungagung
Authors: Mochlisin Fatkur Rohman
Published: December 2021

Indonesia memiliki banyak kekayaan alam yang dapat dimanfaatkan sebagai wisata alam atau desa wisata. Salah satu pengembangan desa wisata ada di Desa Bono, Kecamatan Boyolangu, Kabupaten Tulungagung. Wisata tersebut bernama Wisata Edukasi Pertanian Kelompok Tani Belimbing Artha Mandiri. Wisata edukasi pertanian sangat berpotensi dikunjungi oleh wisatawan karena kualitas produk dan ilmu yang diberikan kepada pengunjung. Pengelola wisata edukasi pertanian harus mengunggulkan edukasi pertanian dalam wisatanya, karena wisata edukasi bertujuan untuk mengedukasi pengunjung terkait ilmu pertanian, maka pembaharuan media komunikasi perlu dilakukan agar dapat menunjang tercapainya tujuan tersebut. Tujuan dari penelitian ini adalah untuk mendeskripsikan karakteristik pengunjung serta menganalisis  pengaruh karakteristik pengunjung dan integrasi media komunikasi terhadap pengetahuan pengunjung.  Metode penelitian yang digunakan adalah Kuantitatif Deskriptif. Penentuan sampel responden menggunakan teknik proportionate stratified random sampling, serta analisis data yang digunakan adalah regresi linear berganda. Hasil penelitian ini menunjukkan tingkat pengetahuan pengunjung berada pada tahap memahami dan adanya pengaruh yang signifikan antara variabel karakteristik pengunjung dan integrasi media komunikasi terhadap tingkat pengetahuan pengunjung.
CONTEMPORARY REPRESENTATIONS ABOUT IRON HOMEOSTASIS IN THE HUMAN BODY
Authors:   Khanty-Mansiysk State Medical Academy, Aliyev Alim Maratovich , Vladimirov Nikolay Mikhailovich , Sokolova Tatiana Nikolaevna , Petrovskaya Yulia Amanzholovna , Leonov Vadim Viacheslavovich
Published: December 2021

Iron is a necessary element for all living organisms, since it is part of the functional groups of oxygentransporting proteins and enzymes that catalyze energy generation reactions and metabolic processes. New research in the fi eld of iron homeostasis has allowed to learn in more detail the molecular mechanisms of absorption, export, transport, storage, recycling of iron, the mechanisms of regulation of iron metabolism in mammals at the cellular and systemic level are disclosed in detail. This article summarizes modern scientifi c data on iron homeostasis at all stages, from absorption to recycling
Resilience and Challenges of Working Mothers during COVID-19
Authors: Heifetz Marina
Published: December 2021

The pandemic has brought on much hardships and highlighted the many inequities in our lives, including the increasing workload for working mothers. Compared to pre-pandemic, maternal research has found mothers to have increases in anxiety and depression during the pandemic. Given the added stressors of the pandemic, this paper aims to highlight some evidence-based strategies that mothers can use to support their mental health during the pandemic and beyond. These mental health strategies include (1) Self-compassion and mindfulness (2) Physical self-care (sleep and physical activity time); (3) Connecting time (maintaining social connections and shared responsibilities); and (4) Playtime (having fun!).
ВІКОВА СТРУКТУРА ПІДРОСТУ CARPINUS BETULUS L. У КУЛЬТУРФІТОЦЕНОЗАХ НАЦІОНАЛЬНОГО ДЕНДРОЛОГІЧНОГО ПАРКУ «СОФІЇВКА» НАН УКРАЇНИ
Authors: Porokhniava O. L. , Hrabovyi V. M. , Muzyka H. I. , Rumiankov O. Y.
Published: December 2021

The issue of preserving the dendrological structure in historical parks requires the implementation of a number of agronomic measures aimed at ensuring the decorative and durability of plant communities. The plants of Carpinus betulus L. are included in the vast majority of deciduous plantations of the National Dendrological Park «Sofiyivka» of NASU, form the stands with the participation of Quercus robur L., Acer platanoides L., Acer campestre L. and Fraxinus excelsior L. The question of self-recovery of C. betulus plants in the park is relevant in connection with natural waste and active reduction of its viability identified over the past 10 years. The analysis of the success of natural regeneration of aboriginal plants in the cultural phytocenoses of the National Dendrological Park «Sofiyivka» of NASU has been conducted. As a result of the survey of the dendrological structure, viability of the young growth of the main structure-forming species under the stand was revealed. The prospects of replacing senile plants of C. betulus with the younger generation have been outlined. The young growth of C. betulus is 4.5% of the total number of viable undergrowth in the test plots, which is significantly less compared to A. platanoides – 64.5 % and A. campestre – 20. 7%. There is a sufficient number of viable virginile and young generative plants of C. betulus, which in future is able to form a stand. Prospects for natural regeneration of plants of the C. betulus species are average, similar in quantitative and age characteristics to plants of the Fraxinus excelsior L. The number of virginile plants is 0.5 %, and young generative – 0.1 %, compared with A. platanoides and A. campestre, the results are more than 10 times lower for virginile and 2 times – for young generative plants, which indicates a weak competitiveness of the young growth of C. betulus. Artificial phytocenoses with the participation of C. betulus are one of a few self-regenerating species in the park, as aboriginal species have a higher adaptive potential and are capable of successful renewal. Control over the ratio of species and quantitative composition of undergrowth, timely rational sanitary and landscape felling will create optimal conditions for growth and development of the young growth of C. betulus. Regular removal of aggressive plants of A. platanoides, A. campestre and F. excelsior will help preserve the existing structure of the stand in the historic part of the NDP «Sofiyivka».
ОСОБЛИВОСТІ ФУНКЦІОНАЛЬНОГО СТАНУ ОРГАНІЗМУ І ОБРОБКИ СЕНСОРНОЇ ІНФОРМАЦІЇ В ОСІБ ЮНАЦЬКОГО ВІКУ
Authors: Voloshyn О. S. , Hoviak M. V. , Popadiuk O. V.
Published: December 2021

The aim of the work is to study the functional indicators of the cardiovascular and respiratory systems, indicators of the efficiency of processing of visual information and motor response in adolescents with different levels of functional reserves of the heart. We studied indicators of heart rate, blood pressure, Skibinsky index, Rosenthal’s test, the speed of the visual-motor reaction (simple and differentiated), the number of errors made during the examination, the analysis of the indicators of the correction test, the volume of operational visual memory, the dynamics of the analysis of Schulte tables, the volume and distribution of attention. The study demonstrated that the functional indicators of the cardiovascular system are within the permissible limits. However, the heart rate of individuals with a satisfactory level of heart efficiency tends to approach the upper physiological limit. Skibinsky’s index corresponds to a satisfactory level for the females. This index indicates the average potential of the external respiration system and the correspondence of activity with the blood circulatory system. For the analysis of Schulte tables, the individuals of the first group spent 161.8 s ± 10.37 s, which is significantly faster than the index of the second group. Studies have not shown a relationship between the level of heart performance and indicators of the distribution of attention. However, the indicators of the volume of operative visual memory in individuals of the first group are much better: 65 % of individuals have a high level (the same index in the second group is 20 %), the participants with a low level of operative visual memory are absent, in contrast to the second group. The speed of simple and differentiated sensorimotor reactions in individuals of the first group is higher than those in the second group by 11.4 % and 10.6 %, respectively. This indicates a sufficient level of plasticity of nervous processes and the efficiency of arousal development. The performance indicators of the cardiovascular and respiratory systems, the speed of reactions of the nervous system of the examined, the efficiency of processing sensory information indicate the maturity of the functional systems of the body and are the physiological basis for the formation of an adequate functional state of the body. Individuals with a Rufier index level above the average showed less tension in the work of the heart and an effective course of sensorimotor reactions, indicating a sufficient level of plasticity of nervous processes.
A pénzügyi kirekesztődés a digitális fizetési térben
Authors: Somogyvári Márta
Published: December 2021

A fizetési rendszerek digitalizálódása egyre gyorsul és feltartózhatatlannak tűnik. Ma vegyes, a készpénzre és a digitális pénzre épülő fizetési rendszereket használunk, de egyre több jegybank vizsgálja a digitális jegybanki pénz bevezetésének lehetőségét és a teljes digitalizációt is. Ennek legnagyobb gátja nemcsak a forgalomban levő készpénzmennyiség növekedése, hanem azoknak a társadalmi csoportoknak a helyzete is, amelyek nem használnak elektronikus fizetési módokat, kirekesztődnek a pénzügyi szolgáltatásokból. Ennek a jelenségnek több oka is van, ide tartozik a gazdasági és az intellektuális hozzáférés nehézsége, a digitális és pénzügyi jártasság alacsony szintje, a bankok üzletpolitikája, valamint a digitális infrastruktúrához történő hozzáférés nehézségei. A pénzügyi kirekesztődés mérséklésében segíthet a digitális hozzáférés szubvencionálása, a különböző nevelési oktatási programok, de a legátütőbb megoldást azok a fejlesztések jelenthetik, amelyek mesterséges intelligencia segítségével helyettesítik a személyes kapcsolatot. Ehhez gyors, biztonságos, transzparens, a pénzügyi kirekesztődés által érintett heterogén csoportok sajátosságait figyelembe vevő innovációkra van szükség.
The effect of lubricants with mineral additives on friction in supports of spindle assemblies
Authors:   Irkutsk State Transport University, Ilyinykh V. A.
Published: December 2021

Currently, the task of increasing the reliability and wear resistance of mechanisms and machines is being solved on the basis of the use of new composite materials. The most effective method of obtaining composite materials is the use of geological activators, which are introduced into the friction zone of the components of mechanisms and machines through a lubrication system, which allows increasing the micro-moisture of the friction surfaces up to 2,3 times, as well as reducing friction in sliding and rolling bearings. According to the research results, it is found that the use of repair and restoration technologies in friction pairs leads to energy savings of 10–20 %, an increase in wear resistance by 2,5 times, an increase in the resource of lubricants by 2,5–5 times, a significant reduction in vibration noise, as well as an increase in the inter-repair resource by at least 2 times and a reduction in operating costs. However, for the widespread introduction of these technologies, additional studies are needed, which are given in this paper.
Mapping positional accuracy for milling machine table
Authors:   Omsk State Technical University, Blokhin D. A. , Blokhina Yu. A. ,   Omsk State Technical University, Lakman M. M. ,   Omsk State Technical University
Published: December 2021

The article presents a technique for compiling a map of the positional accuracy of the table of a vertical milling machine when a vibration load of various frequencies is applied. A laboratory setup for creating forced oscillations of a cross table has been developed and manufactured. The reasons for the emergence of the highest deviations in specific areas of the working area of the machine tool are analyzed.
Research of partial discharge characteristics features in bushings
Authors:   Omsk State Technical University, Polyakov D. A. , Tereshchenko N. A. ,   Omsk State Technical University, Nikitin K. I. ,   Omsk State Technical University
Published: December 2021

The paper is devoted to partial discharge measurement and analysis in switchgear bushings. PD bushing structure analysis is described to assess possible defect sources in bushings. An experimental 10 kV bushing sample with the natural defect is obtained from the bushings’ manufacturer. It is tested using the PD measurement technique. Test results showed significant PD intensity at voltages from 12 kV and higher. We have an assumption that a part of registered discharges occurred in the air close to the high voltage electrode sharp edges. To check this assumption we grind them off and repeated the test. The second test does not show considerable PD characteristics change. Therefore, we assume that the bushing sample has an inner defect because the bushing’s surface is not contaminated to generate surficial discharges. The bushing is researched by a destroying method for defect localization. However, inside the bushing, possible defect locations are not found. It might be connected with the fact that the defect could not be found visually at the test time or the defect is located in the gasket between the high voltage electrode and insulator’s body. Besides, there are determined features of phase-resolved partial discharge patterns in switchgear bushings.
Detection acoustic signals of partial discharges on defects in high voltage insulation
Authors:   Kazan State Power Engineering University, Ivanov D. A. , Galieva T. G. ,   Kazan State Power Engineering University, Golenishchev-Kutuzov A. V. ,   Kazan State Power Engineering University, Sadykov M. F. ,   Kazan State Power Engineering University, Kalimullin R. I. ,   Kazan State Power Engineering University, Semennikov A. V. ,   Kazan State Power Engineering University
Published: December 2021

The article is devoted to the method of acoustic registration of partial discharges in high-voltage insulators. Physical processes of generation of various types of partial discharges in high-voltage insulators are considered. The instrumental implementation and method of processing diagnostic information from sensitive elements — acoustic receivers of the ultrasonic range are described. The ability to detect sources of partial discharges with reference to the place of origin is important for localizing a faulty element and its further diagnosis.
SOFT LAW AND SOVEREIGNTY – FROM A POLITICAL TO A LEGAL LIMITATION
Authors: Avramović Dragutin
Published: December 2021

Firstly, the author analyses the theory of sovereignty from the point of its birth and then he considers more recent theoretical challenges facing the notion of sovereignty in a globalised world. Particular attention is paid to soft law – that new, formally non-binding source of international law in the light of its factual influence on the desovereignisation of states. The author holds the position that the relativisation of the notion of sovereignty has been a process that began already in the 18th century and that has only additionally accelerated with new challenges posed by globalisation. The author argues for the only possible and proper use of the notion of sovereignty in its original meaning as an absolute, completely unlimited, and indivisible power. On the other hand, he takes a critical approach not only to the theory of constitutional pluralism but also to the ideas of the state’s legal sovereignty. He pleads for rejection of separating different aspects of sovereignty, artificially distinguishing between the factual and legal sovereignty, as well as the external and internal sovereignty. While theoretically possible, it is of no practical use because the notion of sovereignty can only be correctly understood as a political and legal illimitability. For all other various modalities and attempts at relativising and grading sovereignty, from the 18th century to this day, different terms should be coined. Being mindful of the situation in most of the present-day states, the author advocates the introduction of the term "pseudo-sovereignty".
Cryotechnology to ensure fire and environmental safety of gas station tanks
Authors:   Main Directorate of EMERCOM of Russia in the Moscow Region, Andyamov V. V. , Rubtsov V. V. ,   Academy of State Fire Service of EMERCOM of Russia
Published: December 2021

Introduction. The principles of comprehensive fire and environmental safety of gasoline tanks using cryogenic technology in the installation of environmental and fire safety on the example of gas stations are substantiated. Goals and objectives. Substantiation of the principles of comprehensive provision of fire and environmental safety of gasoline tanks at filling stations using cryogenic technology in the installation for ensuring environmental and fire safety (OEEFS). Methods. Fire and environmental safety of closed containers for storing liquid hydrocarbons (in our case, gas station tanks) can be ensured by: - recirculation of vapors in closed volumes - "gas tank-reservoir"; - capturing hydrocarbon vapors on breathing fittings; - dilution of the vapor phase in the gas space of the tank to reduce the emission of vapor-air mixtures to the outside; - phlegmatization of the vapor-air space of the reservoir with inert gases; - combining these methods (the method reflected in the application of OEEFS). Results and discussion. A diagram of the application of cryotechnology in the construction of an installation for ensuring environmental and fire safety is shown in Fig. one. Conclusions. Despite the objective pros and cons of a particular recovery technology, the final choice depends on the specific operating conditions of the equipment at the facility: the technically achievable level of minimizing emissions, logistics chains, types and characteristics of raw materials, etc. Therefore, to achieve maximum efficiency and versatility, our technological scheme includes the use of an additional unit: carbon-vacuum adsorption, liquid absorption or membrane module. Keywords: gas stations, fire safety, cryogenic technology, gasoline, environmental safety
A comprehensive method for studying the degree of thermal damage to steel elements of vehicles using field methods
Authors:   Saint-Petersburg University of State Fire Service of EMERCOM of Russia, Motorygin Yu. D. , Sikorova G. A. ,   Saint-Petersburg University of State Fire Service of EMERCOM of Russia
Published: December 2021

Introduction. Every year, the number of registered motor vehicles in Russia increases, with an increase of 30 % over the past 10 years. The desire to extend the service life of existing vehicles leads to an increase in breakdowns that lead to fire. The task of identifying places where there was an emergency situation that led to a fire is difficult, especially in the case of a complete burnout of the fuel load of the car. Goals and objectives. The purpose of the work is to create a methodology by which it is possible to conduct studies of cold-formed steel products of the vehicle body to determine the zone of the greatest thermal damage. Each method determines one of the characteristics that changes when the steel is exposed to high temperatures. The main task of the work is to test the possibility of applying these methods in a certain sequence to determine the zone that has undergone more annealing. Research methods. The complex method includes induction thickness measurement, which allows measuring the thickness of a layer of high-temperature oxide; a method for measuring the coercive force or demagnetization currents, as well as a method for measuring microhardness. The latter method will determine the decrease in the hardness of the vehicle body after exposure to high temperatures. Results and its discussion. The obtained data on the degree of thermal damage to cold-deformed steel products of the car body by three independent field methods will increase the reliability of the combustion start zone, which in turn will determine the search zone for the cause of ignition. Conclusion. Determining the specific cause of the fire during the maintenance, repair and operation of vehicles will allow you to exclude similar emergency modes in the future. The introduction of a comprehensive method for investigating the condition of an object after a fire will significantly increase the level of reliability of the results obtained when searching for a breakdown that led to a fire. Keywords: fire source, car body, thermal changes, field methods, complex technique, magnetic properties, scale thickness, microhardness
Example of modeling the use of fire-fighting vessels
Authors:   Research Institute (Military-System Research of Material and Technical Support of Armed Forces of the Russian Federation) of Military Academy of Material and Technical Support, Kulagin A. V.
Published: December 2021

Introduction. The article considers a systematic approach to assessing the effectiveness of the preparation and use of fire-fighting vessels. Using the Pattern method, a study of the use of a fire-fighting boat for solving problems of extinguishing fires on water transport was conducted. Goal and objectives. The purpose of the study is to improve the methodology for determining the effectiveness of the preparation and use of fire-fighting vessels according to the selected evaluation criteria, with the determination of the impact of each criterion on the overall effectiveness of fire extinguishing. Methods. In the article, the process of evaluating the effectiveness of the preparation and use of fire-fighting vessels can be divided into two stages. At the first stage, a verbal presentation of the research task is carried out with the identification of the most "weak" training measures and during the application of fire-fighting vessels using the Pattern Method. At the second stage of the study, an assessment of the state of the identified "weak" measures is carried out with the definition of measures to improve the technical readiness of the material part or organizational and technical measures during the operation of fire-fighting vessels. Results and discussion. The author obtained a particular analytical solution for improving the efficiency of operation of fire-fighting vessels for the case of using a fire-fighting boat. A method for calculating the evaluation criteria is proposed. Conclusions. Thus, the proposed modification of the model of preparation and application of fire-fighting vessels consists in the representation of organizational and technical processes in the form of a logical "tree of goals". The directions of further research in terms of the development of the results obtained in the analysis of the operation of fire-technical equipment on fire-fighting vessels and fire-fighting vessels themselves are determined. Keywords: model, system approach, analysis, pattern method, diesel, special fire extinguishing means
Gejala Depresi Tokoh Utama dalam Novel Represi Karya Fakhrisna Amalia
Authors: Siti Maemunah
Published: December 2021

Symptoms of Depression in the Main Character in Fakhrisna Amalia's Refresi Novel. According to Aaron Beck, the problem in this study is more focused on the main character's depressive symptoms, who analyzes his depressive symptoms through 4 depressive symptoms. The method used in this research is qualitative. The reason for using this method is that the data presentation and data analysis in this study are presented in sentences and descriptions. The data used in this study are excerpts from dialogues from primary data sources, namely the novel Represi by Fakhrisna Amalia. The secondary data sources are obtained from reference books or documents related to the research object by reading, studying, and understanding. The data collection technique used is to collect data using reading and note-taking techniques. Read the entire contents of the novel carefully, mark the essential things in the novel, describe all the data that has been obtained from the data. In collecting the data, the form of sentences containing the psychological aspects of the main character in the novel Refresi by Fakhrisna Amalia, which is described. Based on the research results conducted in the novel Represi by Fakhrisna Amalia, there are symptoms of depression experienced by the main character: emotional, cognitive, motivational, and physical symptoms.
Multiple Linear Regression and Deep Learning in Body Temperature Detection and Mask Detection
Authors: Najib Abdullah Faisal , Fauzan Mohamad Nurkamal , Riza Noviana
Published: December 2021

In this new normal era, many activities began to operate again, such as offices, malls, etc. This creates a potential mass crowd. The public must follow health protocols as recommended by the government, including wearing masks and checking the temperature to anticipate the spread of the coronavirus. This study tested a tool that included image processing and artificial intelligence to help implement health protocols as recommended by the government. This tool connects Raspberry PI, Thermal Camera (amg8833), Pi Camera, an ultrasonic sensor with Multiple Linear Regression and Deep Learning algorithms. The purpose of this tool is to detect body temperature and detect the use of masks. The system will check on the pi camera frame whether the person is wearing a mask or not. The system is trained using the Deep Learning method to detect the use of masks. The system will check the temperature of the human body and the distance between humans and the tool. Temperature and distance data are entered in multiple linear regression formulas to get more accurate results. The processed results of the system will be displayed on the monitor screen if detected using a mask and the normal temperature will be green and if it is not detected it will be red and give a warning sound. The data is sent to the server and displayed via the web. We found that this tool succeeded in detecting body temperature within a distance of 1 to 3 meters with an accuracy of 99.49%, detecting people using masks with an accuracy of 94.71%, and detecting people not wearing masks with an accuracy of 97.7%.
Evaluation of Site-Diversified, Fully Functionalized Diazirine Probes for Chemical Proteomic Applications
Authors: Tan Yan , Fu Songsen , Yang Tao , Xie Yuxin , Shen Guyi , Yan Jie , Ni Feng
Published: December 2021

Photoaffinity probes combined with the chemical proteomic platform have emerged as versatile tools for ligand and target discovery. However, photoaffinity probes with retained activity cannot always label the known target, indicating that it is challenging to profile a ligand’s targets based on its photoaffinity probe modified at a single site. Herein, we construct a series of site-diversified probes (P1-P6) of 4-anilinoquinazoline, a scaffold shared by several marketed EGFR-targeted drugs, via attaching a “fully functionalized” diazirine tag to six different sites, respectively. Chemical proteomic analysis revealed that these probes show different proteome-wide profiles and distinct competition patterns by erlotinib. Remarkably, low activity P4 towards EGFR inhibition has better EGFR labelling efficiency than the higher one, P5, which highlights the dominance of labelling accessibility of diazirine over probe affinity. In addition, the integrated analysis of protein targets of site-diversified probes can also help distinguish false positive targets. We anticipate that site-diversification of the probes of a given scaffold is an indispensable strategy to truly harness the power of photoaffinity-based chemoproteomics in drug discovery.
Cyclometalated Iridium-Coumarin Ratiometric Oxygen Sensors: Improved Signal Resolution and Tunable Dynamic Ranges
Authors: Wu Yanyu , Sutton Gregory D. , Halamicek Michael D. S. , Teets Thomas S.
Published: December 2021

In this work we introduce a new series of ratiometric oxygen sensors for hypoxic environments based on phosphorescent cyclometalated iridium centers partnered with organic coumarin fluorophores. Three different cyclometalating ligands and two different pyridyl-containing coumarin types were used to prepare six target complexes with tunable excited-state energies. Some of the complexes exhibit only phosphorescence originating from the cyclometalated Ir moiety, as a result of excited-state energy transfer from the coumarin to the Ir-centered excited states. Three of the complexes display dual emission, with fluorescence arising from the coumarin ligands and phosphorescence from the cyclometalated iridium synthons, and hence function as ratiometric oxygen sensors. Oxygen quenching experiments with these complexes demonstrate that the iridium centered phosphorescence is quenched under O₂ while fluorescence is unaffected. These sensors have good signal resolution, and the sensitivity and dynamic range, measured with Stern-Volmer analysis, span two orders of magnitude. This work demonstrates that this simple, modular approach for conjoining fluorescent and phosphorescent molecules can produce effective oxygen sensors with a wide range of attributes.
Phase-field investigation of lithium electrodeposition under different applied overpotentials and operating temperatures
Authors: Jeon Joonyeob , Yoon Gil Ho , Vegge Tejs , Chang Jin Hyun
Published: December 2021

Despite the high promise, the commercialization of Li-metal-based batteries has been hampered due to the formation of dendrites that lead to mechanical instability, energy loss and eventual internal short circuits. The mechanism of dendrite formation and the strategies to suppress their growth have been studied intensively. However, the effect of applied overpotential and operating temperature on dendrite growth remains to be fully understood. Here, we elucidate the correlation of overpotential and temperature with the surface modulation during electrodeposition using phase-field simulations. We identify an optimal operating temperature of half-cell consisting of a Li metal anode and 1M LiPF6 in EC:DMC(1:1), which increases gradually as the overpotential increases. The investigation reveals that the temperature dependence identified in the simulations and experiments often disagree because they are primarily conducted in galvanostatic and potentiostatic conditions, respectively. The temperature increase under potentiostatic conditions increases the induced current while it decreases the induced overpotential under galvanostatic conditions. Therefore, the analysis and comparison of temperature-dependent characteristics must be carried out with care.
Low quantum efficiency of μ-oxo iron bisporphyrin photoacatalysts explained with femtosecond M-edge XANES
Authors: Sye Kori , Leahy Clare , Vura-Weis Josh
Published: December 2021

Bridged μ-oxo iron bisporphyrins serve as photocatalysts for oxidative organic transformations, but suffer from low quantum efficiency. We use femtosecond optical and M2,3-edge XANES spectroscopy to investigate the early photodynamics of the μ-oxo iron bisporphyrin, (TPPFe)2O, providing evidence for the preferential formation of an TPPFe(III)+/TPPFe(III)-O- ion pair state instead of the desired TPPFe(II)/TPPFe(IV)=O.
El arte popular del centro del Perú: un proceso histórico
Authors: Fabián Arias Beatriz Anastacia
Published: December 2021

La investigación tuvo por objetivo determinar las principales características del arte popular en la región central del Perú y en Lima Metropolitana. Es una investigación cualitativa, tipo aplicada, nivel exploratorio, método etnográfico, diseño no experimental. Los instrumentos utilizados fueron la guía de entrevista y guía de observación; la epistemología que sustenta la investigación es la teoría histórico-cultural de Lev Semionovich Vigotsky. La muestra representativa fueron 20 participantes de la región central del Perú y Lima Metropolitana como integrantes de las orquestas típicas, artistas populares y consumidores de la cultura.
Impacto del blog en la producción de textos argumentativos en estudiantes de educación secundaria
Authors: Chura Quispe Gilber , Villacorta Castro Nay Ruth Madeleyne
Published: December 2021

El problema de investigación se enfocó en las deficiencias de la producción de textos argumentativos (PTA) en la formación básica. El objetivo del estudio fue determinar si con la aplicabilidad del blog mejora el nivel de PTA en estudiantes de VII ciclo de educación básica de una institución educativa de Tacna. La investigación fue de tipo aplicada y con diseño preexperimental. Se aplicó el muestreo no probabilístico intencional y se seleccionó a 32 estudiantes entre cuarto y quinto grado de secundaria. El instrumento fue una rúbrica para evaluar la PTA validado por jueces expertos. Los resultados demuestran un incremento del 65,62 % de estudiantes en nivel satisfactorio y una disminución del 62,49 % del nivel inicio. Con un p-valor (0,00) menor al nivel de significancia (0,05), se comprobó que existe mejora significativa de la propuesta sobre el nivel de PTA.
Gestión pedagógica y satisfacción de los usuarios en la Facultad de Educación de la Universidad Nacional de Huancavelica
Authors: Oré Rojas Juan José , Hoces la Rosa Zeida Patricia
Published: December 2021

El principal objetivo de esta investigación fue establecer la relación o correspondencia entre la gestión pedagógica y la satisfacción de los usuarios en la Facultad de Educación de la Universidad Nacional de Huancavelica. Este estudio se enmarca dentro de las investigaciones descriptivas correlacionales. Los datos estadísticos que sostienen esta investigación vienen de los resultados obtenidos mediante la aplicación del cuestionario para valorar la gestión pedagógica y cuestionario para valorar la satisfacción de los usuarios. Finalmente se concluye que los estudiantes se muestran poco satisfechos con los diferentes aspectos del quehacer educativo de los docentes.
Los instrumentos de la investigación científica. Hacia una plataforma teórica que clarifique y gratifique
Authors: De la Lama Zubirán Paula , De la Lama Zubirán Marco A. , De la Lama García Alfredo
Published: December 2021

Este artículo describe el estado del arte de los instrumentos de la ciencia y valora su utilidad, sus potencialidades y también sus limitaciones. Propone criterios para seleccionarlos y así llevar a la práctica la investigación. Aborda las discusiones teóricas en torno a los instrumentos cualitativos y cuantitativos; y presenta otra manera de clasificarlos al mostrar que cumplen las exigencias de la replicabilidad, en ciertas circunstancias. Dado que el trabajo de campo, documental y experimental es una de las facetas fundamentales de la investigación se sugiere hacerlo con espíritu lúdico para alcanzar un grado de satisfacción sólo observado en las actividades creativas.
Temporomandibular eklem düzensizlikleri teşhisinde kullanılan görüntüleme yöntemleri
Authors: ADAM ERDEN Ayşe Canan , KARAKIŞ Duygu
Published: December 2021

Temporomandibular eklem düzensizliği, çiğneme kasları ile eklemin sert ve yumuşak dokularını etkileyen ve toplumda yaygın gözlenen bir hastalıktır. Teşhise karar verme sürecinde anamnez ve klinik muayene yanında radyolojik değerlendirme de yapılır. Temporomandibular eklem görüntülenmesinde, sert ve yumuşak dokuların anatomik bütünlüğünün değerlendirildiği ya da metabolik değişimlerin incelendiği çeşitli görüntüleme yöntemleri kullanılmaktadır. Kullanılacak yöntem patolojiye uygunluk, radyasyon dozu, maliyet, yararlılık, ulaşılabilirlik gibi faktörlere göre seçilmelidir. Bu derlemede temporomandibular eklem yapılarının değerlendirilmesinde kullanılan direkt radyografi yöntemlerinden panoramik, transkraniyel, transfaringeal, transmaksiller, submentoverteks, transorbital, reverse towne, posterior-anterior radyografileri, lateral ve posteroanterior sefalometri, dijital substraksiyon radyografisi ile dijital floroskopi, konvansiyonel, bilgisayarlı ve konik ışınlı bilgisayarlı tomografi, manyetik rezonans görüntüleme, artrografi, ultrasonografi ve radyonüklid görüntüleme yöntemleri incelenmiştir. Yöntemlerin endikasyonları, avantaj ve dezavantajları özetlenmiş ve birbiri ile karşılaştırıldığı çalışmalardan bahsedilmiştir.
THE ROLE OF PHYSICAL ELEMENT SETTINGS ON THE ACTIVITIES OF THE URBAN TOURISM VILLAGE STUDY OBJECT: KAMPUNG LAWAS MASPATI AND KAMPUNG PELANGI KENJERAN
Authors: Arief Anjasmoro Dionisius , Basuki Dwisusanto Yohanes
Published: December 2021

Abstract - Indonesia has a variety of urban tourism village scattered in various regions. The tourism village has various themes according to the character of the are and the residents of the village. Such as Batik Village, Ceramic Village, Rainbow Village, etc. The presence of the concept of an urban tourism village doesn not only occur in Indonesia, but also occurs in various other countries such as Gamcheon Culture Village in Korea, Chefchaouen in Marocco, Marsaxlokk Village in Malta, etc. With the presence of the concept of tourism village, it provides novelty for both humans (tourist and villagers) as the users of space accompanied by their activities.

Based on these problems the authors are interested in conducting this research. This research will discuss about what is meant by a tourist village, how tourism activities occur in the two study objects and how architecture as a physical element plays a role in the activities in it. The purpose of this study is to describe how far a village called a tourist village is feasible as a tourist place by introducing the tourism criteria, what are the criteria for a village to be called a tourist village. This research is a descriptive qualitative research, using Kampung Lawas Maspati and Kampung Pelangi Kenjeran as objects of study to be compared based on the tourism criteria itself, to further examine how the physical (architectural) element settings play a role in accommodating tourism activities in the village itself. So that how far the two objects of study meet the existing tourist criteria so that they are feasible as tourist attractions. With this research, it is hoped that it can provide an understanding of what is meant by a tourist village and the importance of the role of architecture in realizing the tourism village it deserves.

The results of the research show that the physical elements in Kampung Lawas Maspati meet the three criteria that a tourism village needs to have and there are tourism activities organized by local village managers, while Kampung Pelangi Kenjeran has not fulfilled existing tourism criteria, the availability of physical elements in Kampung Pelangi Kenjeran is very minimal. This proves that the term "tourism" in Pelangi Kenjeran village is still not appropriate as it should be.

 

Key Words: setting, physical elements, activity, urban tourim village
Onde está Maria Beatriz Nascimento na história da Educação? Algumas reflexões sobre apagamentos e direito à memória
Authors: Freitas Rosineide
Published: December 2021

Este trabalho tem por objetivo contribuir com as reflexões sobre a importância de intelectuais negras para as pesquisas em História da Educação, a partir da trajetória de Maria Beatriz Nascimento, historiadora e intelectual negra do tempo presente. Pela grandiosidade, importância histórica dos arquivos pessoais e produções desta autora, entende-se como emergente que estudos e pesquisas em história da educação dediquem-se à análise contextualizada destas fontes, bem como das suas contribuições intelectuais.
EFEK EDUKASI KARTUN ISLAMI TERHADAP KECERDASAN SPIRITUAL ANAK SDN 1 PURWOSARI KABUPATEN KUDUS
Authors: Risnawati Indah , Sukarmin Sukarmin , Karyati Sri , Zuliana Zuliana
Published: December 2021

Latar Belakang : Kecerdasan spiritual adalah aplikasi adaptif spiritualitas dalam kehidupan sehari-hari. Ini melibatkan menggunakan spiritualitas dalam memecahkan masalah, membuat rencana dan beradaptasi tentang hidup. Azzet 2010, upaya dalam meningkatkan dan mengembangkan kecerdasan spiritual bisa dilakukan dengan membimbing anak menemukan makna hidup dengan cara berpikir positif, melatih anak untuk berbuat baik kepada semua orang tanpa mengharapkan suatu imbalan, dan melibatkan anak dalam beribadah dengan keimanan serta kesadaran yang tumbuh dari pribadi anak. Tujuan : Tujuan dari penelitian ini adalah untuk mengetahui efek Edukasi Kartun Islami Terhadap Kecerdasan Spiritual Pada Anak SD N 1 Purwosari Kabupaten Kudus . Metode : Metode penelitian ini menggunakan Quasi Experiment yang berdesain pre test-post control group. Teknik sampling dalam penelitian ini diambil secara Non Probability Sampling dengan metode Purpossive Sampling. Jumlah sampel 32 responden yang merupakan siswa SD kelas 5 di SDN Purwosari Kudus. Analisis data menggunakan uji Wilcoxon dan Mann Whitney. Hasil : Hasil penelitian menunjukkan adanya perbedaan yang signifikan pada kecerdasan spiritual sebelum dan sesudah edukasi kartun islami dengan p value sebesar 0,034 < α (0,05). Kesimpulan : Terdapat perbedaan Pengaruh Edukasi Kartun Islami Terhadap Kecerdasan Spiritual Pada Anak Kelas V di SD N 1 Purwosari Kabupaten Kudus.
HUBUNGAN PHBS DENGAN KEJADIAN SCABIES DI PONDOK PESANTREN NGANGKRUK DESA BANDUNGSARI NGARINGAN KABUPATEN GROBOGAN
Authors: Nurlaily Nurlaily , Priyantiningsih Dewi
Published: December 2021

Latar belakang: Scabies merupakan infeksi parasit pada kulit yang disebabkan oleh Sarcoptes scabei var hominis.Salah satu faktor permasalahan yang berakibat pada masih tingginya angka penyebaran penyakit di pondok pesantren adalah pola perilaku hidup bersih dan sehat (PHBS) yang masih rendah.Tujuan: Penelitian ini bertujuan untuk mengetahui hubungan PHBS dengan kejadian scabies. Metode: Desain penelitian ini menggunakan pendekatan cross sectional, variabel yang diobservasi yaitu PHBS dan kejadian scabies dengan populasi 650 orang dan sampel 87 orang diambil dengan simple random sampling. Analisis data menggunakan uji Chi square. Hasil:Hasil penelitian menunjukkan bahwa PHBS responden di Pondok Pesantren Ngangkruk Desa Bandungsari Ngaringan Kabupaten Grobogan sebagian besar buruk 49 responden (56,3%) dan kejadian scabies sebagian besar tidak tidak scabies 62 responden (71,3%). Kesimpulan: Terdapat hubungan PHBS dengan kejadian scabies di Pondok Pesantren Ngangkruk Desa Bandungsari Ngaringan Kabupaten Grobogan (p=0,005).
KECEMASAN WANITA PADA MASA MENOPOUSE BERDASARKAN SELF ACCEPATANCE
Authors: Astuti Dwi
Published: December 2021

AbstrakLatar Belakang: Premenopause terjadi pada usia dewasa madya, masa dewasa madya dalam terminologi kronologis yaitu tahun-tahun antar usia 45 dan 65 tahun. Pada masa dewasa madya ini seksualitas mengalami penurunan. Masa dewasa madya ditandai dengan adanya perubahan-perubahan jasmani dan mental. Perubahan kejiwaan yang dialami seorang wanita menjelang prmenopause meliputi merasa tua, tidak menarik lagi, tertekan karena takut menjadi tua, mudah tersinggung, mudah kaget sehingga jantung berdebar, takut tidak bisa memenuhi kebutuhan seksual suami, rasa takut bahwa suami akan menyeleweng, keinginan seksual menurun dan sulit mencapai kepuasaan (orgasme), merasa sudah tidak berguna dan tidak menghasilkan sesuatu, merasa memberatkan keluarga dan orang lain. Tujuan: Mengetahui Hubungan Antara Selt acceptance Dengan Kecemasan Dalam Menghadapi Menopouse Pada Wanita Premenopouse Di Puskesmas gabus II Pati Metode: analitik korelasi dengan pendekatan Cross sectional, sampel seluruh pasien premenopouse di Puskesmas Gabus II Pati usia 40-45 tahun sebanyak 40 orang sebanyak 36 orang. teknik Purposive sampling. Data di analisa dengan uji statistik Chi square. Hasil: Ada hubungan selt acceptance dengan kecemasan dalam menghadapi menopouse pada wanita premenopouse di Puskesmas Gabus II Pati dengan nilai P Value 0,001< 0,05. Kata kunci      : Selt acceptance, Kecemasan, perimenopouseDaftar Pustaka : 39 Daftar Pustaka (2009-2016) ABSTRACTBackground: Premenopause occurs in middle adulthood, middle adulthood in chronological terminology, namely years between 45 and 65 years. During this middle adulthood sexuality has decreased. Middle adulthood is characterized by physical and mental changes. Psychiatric changes experienced by a woman before prmenopause include feeling old, not attractive anymore, depressed for fear of growing old, easily offended, easily shocked so that heart palpitations, fear of not being able to meet the sexual needs of the husband, fear that the husband will deviate, decreased sexual desire and difficult to achieve satisfaction (orgasm), feel it is useless and does not produce something, feel burdensome for family and others. Objective: To find out the relationship between self-acceptance and anxiety in dealing with menopause in premenopouse women in Public Health center Gabus II. Method: analytic correlation with cross sectional approach, a sample of all premenopouse patients in Public Health Center Gabus II, 40-45 years old, 36 people, 36 person. Purposive sampling technique. Data were analyzed by Chi square statistical test. Results: There is a relationship of self-acceptance with anxiety in facing menopause in premenopausal women in Public Health Center Gabus II Pati Health Center area with a P value of 0.001 <0.05