bluuebunny/crossref_metadata_2025 huggingface dataset:
Order of medicines rationing with the provision of qualified surgical help to military servicing
Authors: Bielyozorova O. V. , Shmatenko O. P.
Published: March 2019

The standardization of medicines, taking into account the considerable experience of the military medical service, is a promising direction for improving the medical supply of the health facilities of the Ministry of Defense of Ukraine and provides medical provision in accordance with established norms in order to fully and timely meet the needs of the medical service in the Ministry of Health for the provision of quality and effective medical care and treatment of wounded and sick.

The purpose of the study was the rationale of the method of valuation and a comparative analysis of the proposed norms for supplying medicines to a military hospital and a military mobile hospital offered in the treatment of surgical personnel.

A comprehensive analysis of the medical treatment of soldiers in the surgical section of the military hospital and the military mobile hospital was conducted (345 and 202 persons, respectively), the normative method of the proposed nomenclature and the number of drugs for the provision of qualified surgical care in the conditions of the military hospital and the military mobile hospital.

The nomenclature of medicines under the international non-proprietary names included in the proposed list of norms for the supply of medicinal products and is intended for servicemen of a surgical profile for the needs of military hospitals and military mobile hospitals is 147 and 130 titles of medicines, respectively. In the conditions of the military hospital in the species diversity, the most represented groups are medicinal products that affect the blood system and hemopoiesis (19%), drugs that affect the nervous system (16%), antimicrobials for systemic use (15%); in the conditions of a military mobile hospital ‒ medicines affecting the blood system and hemopoiesis (23 titles), in the second place drugs affecting the nervous system (21 titles), the third means affecting the digestive system and path (19 titles).

Thus, a comparative analysis of the proposed fragment of the delivery of medicines for the needs of the military hospital and the military mobile hospital with approved Temporary Settlement of Medical Assets for the provision of medical care and treatment of wounded and patients for a special period demonstrated the conformity of the nomenclature of drugs to 41% (68 INN medicines for provision of qualified surgical assistance from 167 INN medicines for providing qualified medical aid).
Development of techniques to identify and determine the active ingredient in dental gel composition
Authors: Davtyan L. L. , Reva D. V. , Chubenko O. V. , Trohumchuk V. V.
Published: March 2019

The technique of the qualitative and quantitative determination of active substances – decamethoxine and lidocaine hydrochloride in a new combination drug for preventing and treating inflammatory diseases of the oral cavity was developed.The aim of the work was to develop a methodology to identify and determine the active pharmaceutical ingredient in the composition of the dental gel.The objects were specimens of the developed dental gel containing lidocaine hydrochloride and decamethoxine. The study was conducted using high performance liquid chromatography (HPLC).The conditions for HPLC chromatographic investigations, providing sufficient selectivity and separation efficiency of the gel components were proposed.It was determined that the content of the dental gel component is within acceptable limits, and metrological characteristics of the method allow to recommend it to control the gel quality. 1 gram of the gel contains: decamethoxine – 0.591 mg/g (at a rate of 0.45–0.55 mg/g), lidocaine hydrochloride – 0.396 mg/g (at a rate of 0.36–0.44 mg/g).Approximate retention time of decamethoxine peak is 18.4 min, lidocaine hydrochloride – 13.5 min. Retention time of the peak of decamethoxine and lidocaine hydrochloride investigational solution and reference solution did not exceed 2%.
Antifatigue action of the 5-(furan-2-yl, 2-metylfuran-3-yl)-4-amino-1,2,4-triazole-3-thione alkyl derivatives
Authors: Danilchenko D. M. , Parchenko V. V. , Panasenko O. I. , Knysh Ye. G.
Published: March 2019

Body fatigue has many definitions but in general it can be described as a feeling of heaviness which occurs at the initiation or support physical or mental activities related to work at their normal abilities. Fatigue can be divided into physical and mental fatigue.

Fatigue therapy problem is directed to find effective drugs, which affect the mechanisms of fatigue development and are aimed at restoring the cell functions, in particular, increase enzymes activity of the antioxidant defense system. Thus, pharmaceutical and medical practice is more interested in the tools that can help to improve the body's physical abilities and also to postpone fatigue or accelerate the recovery period of the body, but have fewer side effects.

In our opinion these future drugs could be the 1,2,4-triazole derivatives which have low toxicity and wide spectrum of pharmacological action.

Thus, the objective of our research was to investigate the antifatigue action of 1,2,4-triazole derivatives, as well as establish the patterns between the chemical structure and pharmacological action.

The research was carried out on a group of white non-linear rats weighing 163-214. The study of antifatigue activity has been used forced immersion method in water with a load of 10% of the rats weight.

Among the alkyl derivatives of 5-(2-methylfuran-3-yl)-4-amino-4H-1,2,4-triazole-3-thiones (2a–g) the most expressive antifatigue action had the 3-octylthio-5-(2-methylfuran-3-yl)-4-amino-1,2,4-triazole (2f). Its application had led to the increasing of the forced swimming duration in comparison with the control group to 15.79%.

It should be noted that the 2-methylfuran-3-yl administration to the С5 carbon atom leads to a slight increasing of the antifatigue actions at studied 1,2,4-triazole derivatives.

After analyzing the data, we have established some patterns of dependings on the chemical structure of the antifatigue action of the synthesized compounds. For further in-depth research it is recommended to study the compound 1d, which by its antifatigue effect exceeds the referent Riboxinum.
Identification of β -cyclodextrin inclusion complex by infrared spectroscopy
Authors: Omelchenko I. O. , Yarnyh T. G. , Yanchuk I. B. , Borschevskiy G. I.
Published: March 2019

Fast and reliable identification of obtaining product is very important in the industrial technology of synthesis of pharmaceutical substances.

Objective - to study inclusion complexes of β-cyclodextrin with α-bromizovalerian acid and β-cyclodextrin with mint oil by applying near infrared spectroscopy absorption. Compare the spectra obtained with the spectra of equimolar mechanical mixture of the respective components.

Β-cyclodextrin complexes with α-bromizovalerian acid and β-cyclodextrin with mint oil were prepared at a well-known technique. Mechanical mixture of β-cyclodextrin with α-bromizovalerian acid and β-cyclodextrin with mint oil were obtained by mixing the components in a molar ratio of 1:1.

This paper shows the possibility using method of absorption near-infrared spectroscopy for rapid identification β-cyclodextrin inclusion complexes, as an example used complexes of β-cyclodextrin with α-bromizovalerian acid and β-cyclodextrin with peppermint oil. By comparing the spectra obtained inclusion complexes with the spectra of equimolar mechanical mixture of the corresponding components proved reliability the identification of the target product and the ability to distinguish between an inclusion complex and the mechanical mixture of the components. It is shown that the near infrared spectra obtained using an instrument Thermo Nicolet IS50, Thermo Scientific, inclusion complexes of β-cyclodextrin with a different guest molecules are different from each other.
The researching of antipyretic effect for new S-derivatives 1,2,4-triazoles with morpholinomethylene fragment
Authors: Shcherbyna R. О.
Published: March 2019

It is known that high temperature is a sign or a symptom of the disease. In order to struggle with this disease there are actively used antipyretics. Importantly, this class of drugs along with analgesic and antiinflammatory properties is also exhibits a sufficiently wide range of side effects. Therefore, the search for drugs with high antipyretic activity and low toxicity is very important and actual. Suffice it interesting and promising in this direction are 1,2,4-triazole thioderivatives.

The aim of this research was the pharmacological screening of antipyretics among 4-R-3-(morpholinomethylene)-1,2,4-triazole-5-thiones alkyl derivatives which were synthesized for the first time.

Experimental fever was reproduced on white non-linear rats by administration of 2,4-dinitrophenol in a dose of 20 mg/kg. As reference agent was used an acetylsalicylic acid at 100 mg/kg.

The study found that the compounds that were being studied, and the comparison drug had different effects on body temperature in rats. Thus, among investigated compounds the most active is 3-(morpholinomethylene)-5-decylthio-4-ethyl-4H-1,2,4-triazole (ПКР-227) and its ability to inhibit hyperthermia was more than acetylsalicylic acid and it reduces the temperatures on 2,86 ºC body rats (p ≤ 0,05). Hydrocarbon chain residue elongation at position C5 of 1,2,4-triazole nucleus increases antipyretic activity of the synthesized compounds. Substitution of the phenyl to ethyl radical at the nitrogen atom N4 in the molecules of 4-R-3-(morpholinomethylene)-1,2,4-triazole-5-thiones alkyl derivatives increases antipyretic effect of the synthesized compounds. The obtained results may be used for further new pharmacological tests of 1,2,4-triazole derivatives.
Analysis of the pneumonia morbidity in children in order to optimize pharmaceutical aid
Authors: Trokhimchuk V. V. , Belyaeva O. I.
Published: March 2019

To analyze the health of the child population used  statistical incidence, disease prevalence, their gender features and age characteristics, mortality. According to WHO, among the major causes of child mortality, the share of pneumonia accounts for 19% of all deaths. In Ukraine in the structure of infant mortality pneumonia ranked third.The aim of the work was to study the structure of child morbidity with respiratory diseases and pneumonia in Ukraine and separately of Southern region.

The material of the study are the data of medical statistics. The study used informational, statistical and graphical methods.

The study found that respiratory diseases occupy a leading place in the structure of child morbidity in Ukraine, with a 67.1% share. It was found that the share of children (0–17 years) in 2015 accounted for 65 411 cases of pneumonia (32%). The analysis showed that the incidence of pneumonia is characterized by age and regional differencies. Thus, the highest rates are observed in children aged 0–14 years and of urban children. According to the statistical analysis of the Southern region, in the Kherson region incidence rate of pneumonia was significantly higher than the national average. Conducted analysis of normative documents regulating the treatment of pneumonia in children. It turned out that in documents there are groups of drugs without a specific medication lists. It is necessary to conduct pharmacoeconomic analysis of rational choice of drugs and rational use of healthcare resources.
Biological activity of the derivatives of 1,2,4-triazole
Authors: Kravchenko T. V. , Panasenko O. I. , Knysh E. G.
Published: March 2019

The rapid development of modern medicine and pharmacy leads to an increase in synthetic drugs. Thus, in the professional literature says that one of the perspective directions are searching for new biologically active compounds including heterocyclic systems and the introduction of the latest in medical, pharmaceutical or veterinary practice.

It is known that heterocyclic ring system 1,2,4-triazole moiety is promising for the synthesis of new active ingredients with various kinds of pharmacological actions.

The aim of the study was the analysis of literature and patent sources over the past 10 years and the generalization of the results for certain types of biological activity of 1,2,4-triazole.

Results of literary analysis show a wide range of biological activity of 1,2,4-triazole-3-tion. The data determine the relevance of further research of derivatives of 1,2,4-triazole in the actoprotective, antimicrobial, antifungal, antihypoxic, hypoglycemic, analgesic, antiinflammatory and others activity in order to find new highly effective in terms of biological substances that can form the basis of new medicines.
Synthesis, physico-chemical properties of 2-((4-amino-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazol-3-yl)thio)acetohyd-razides
Authors: Safonov A. A.
Published: March 2019

The value of the class of 1,2,4-triazole derivatives to create a low-toxic and highly active substances is huge. There are a lot of facts about the high biological activity among a number of substances. The 2-((4-amino-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazol-3-yl)thio)acetohydrazides derivatives causes of particular interest in this direction.

The aim of the work was to synthesize 2-((4-amino-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazol-3-yl)thio)acetohydrazides and their derivatives, studying of their physico-chemical properties.

2-((4-amino-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazol-3-yl)thio)-N'-R-acetohydrazides were synthesized by of 2-((4-amino-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazol-3-yl)thio)acetohydrazides with aldehydes and ketones in the i-propanol with the addition of hydrochloric acid.

The melting point was determined by an automatic device for determining the melting point OptiMelt Stanford Research Systems MPA100 (US). The elemental composition of compounds found in elemental analyzer Elementar Vario L cube (CHNS) (standard ‒ sulfonamides). Chromatography-mass spectral studies conducted on gas-liquid chromatograph Agilent 1260 Infinity HPLC with equipped mass spectrometer Agilent 6120, 1H-NMR-spectra were registered on spectrometer Mercury 400

A series of new 2-((4-amino-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazol-3-yl)thio)-N'-R-acetohydrazides derivatives were synthesized, R-2-chloro-6-fluorobenzylidene, 3-nitrobenzylidene, 4-hydroxybenzylidene, 2-nitrobenzylidene, 2,4-dimethylbenzylidene, 3,5-dimethoxybenzylidene, 3-bromo-4-fluorobenzylidene, 2,3-dimethoxybenzylidene, 2-bromobenzylidene, 2-fluorobenzylidene, 4-(dimethylamino)benzylidene, pyridin-2-ylmethylene, 5-nitrofuran-2-ylmethylene, 4-methoxybenzylidene, 2-hydroxybenzylidene, 4-methoxyphenyl)ethylidene, 1-(thiophen-2-yl)ethylidene. The structure of these compounds was established by modern physico-chemical analysis methods (elemental analysis, 1H-NMR spectroscopy). Individuality was proved by HPLC-MS.
Histological study of the influence of antidiabetic plant collection on pancreatic tissue in rats with diabetes mellitus, which is induced by dexamethasone
Authors: Savych A. O. , Marchyshyn S. M. , Ostrovsky N. M. , Laryanovska Y. B.
Published: March 2019

Diabetes mellitus is a global problem today, because there is a sharp increase the number of patients in the world each year. Severe complications of diabetes are very dangerous because it can lead to disability of patients and high mortality.

The aim of our work was to study the protective effect of antidiabetic plant collection on the pancreas in rats with diabetes type 2, caused by the introduction of  dexamethasone.

The research materials were pancreatic tissue of rats with experimental diabetes that received the decoction (1:10) of antidiabetic plant collection (witch includes Equiseti arvensis herba, Sambuci flores, Inulae rhizomata et radices, Hyperici herba, Tiliae flores, Polygoni avicularis herba, Myrtilli folium, Urticae folia) in treatment and preventive mode.  The model of diabetes mellitus was induced by administration of dexamethasone 0.125 ml/kg for 15 days.

Decoction of antidiabetic plant collection in doses 6 ml/kg, 9 ml/kg and 12 ml/kg reduces diabetogenic properties of dexamethasone when administered simultaneously. The insular tissue increases absorbance pancreatic islets, to some extent restored the normal percentage distribution of the islets in size, histologically visualized the increase more high-grade cells.

The study found that antidiabetic plant collection reduces destructive-dystrophic changes of insular apparatus in rats with diabetes type 2. Antidiabetic effect of the studied plant collection has dose-dependent nature. The most effective conditional-effective doses are 9 and 12 ml/kg.
Perlindungan Hukum Konsumen Jasa Medis atas Penelantaran Pelayanan oleh Rumah Sakit
Authors: Ratih Sari Sinta Dewi
Published: March 2019

Sesuai dengan Pasal 28H ayat (1) Undang-Undang Dasar Negara Republik Indonesia Tahun 1945 setiap orang berhak hidup sejahtera lahir dan batin, bertempat tinggal dan mendapatkan lingkungan hidup yang baik dan sehat serta berhak memperoleh pelayanan kesehatan. Maka pemerintah wajib melindungi setiap individu dan menjamin khususnya dalam bidang kesehatan atau yang kerap dikenal dengan jasa medis. Secara umum, perlindungan konsumen diatur dalam Undang-Undang Nomor 8 Tahun 1999 tentang Perlindungan Konsumen. Perlindungan konsumen jasa medis bertujuan untuk melindungi hak pasien atau konsumen jasa medis yang tercantum dalam Pasal 52 Undang-Undang Nomor 29 Tahun 2004 tentang Praktik Kedokteran. Konsumen jasa medis adalah pihak yang membutuhkan bantuan dari penyelenggara sarana dan pra sarana pelayanan medis yang dikenal masyarakat dengan sebutan rumah sakit. Sesuai dengan tugas dan fungsi rumah sakit dalam UU No. 44 Tahun 2009 tentang Rumah Sakit, harusnya menjamin penyelenggaraan pelayanan kesehatan perorangan secara paripurna. Namun, masih cukup banyak terjadi kasus yang melanggar hak konsumen jasa medis khususnya berupa penelantaran pelayanan. Beberapa kasus penelantaran pelayanan terhadap konsumen jasa medis kerap terjadi di Indonesia setiap tahunnya. Adapun rumusan masalah dalam penelitian ini yaitu bagaimana bentuk perlindungan hukum terhadap konsumen jasa medis dalam hukum positif Indonesia dan upaya apa yang dapat ditempuh oleh konsumen jasa medis yang mengalami tindakan penelantaran oleh rumah sakit. Metode yang digunakan dalam penelitian ini adalah metode penelitian hokum normatif atau doctrinal dengan menggunakan data sekunder berupa bahan-bahan hokum seperti putusan-putusan pengadilan, teori-teori maupun konsep dan pandangan para sarjana hokum terkemuka. Pendekatan yang digunakan adalah pendekatan undang-undang statutory approach) dan pendekatan konseptual (conceptual approach).
Notaris Pailit dalam Peraturan Jabatan Notaris
Authors: Puspaningrum Galuh
Published: March 2019

Notaris adalah Pejabat umum yang berwenang untuk membuat akta autentik dan kewenangan lainnya yang diatur dalam peraturan perundang-undangan. Disamping tugas dan wewenang Notaris sebagai pejabat umum, Notaris juga berkedudukan sebagai subyek hukum pribadi (natuurlijk person) yaitu memiliki kehendak bebas untuk melakukan perbuatan hukum. Kedudukan Notaris sebagai subyek hukum ini melibatkan kegiatan pembentukan perusahaan yakni Notaris berkedudukan sebagai direksi dalam bentuk Perseroan Terbatas (PT). Setiap perusahaan memiliki visi keberlanjutan dan keunggulan, namun untuk mewujudkannya diperlukan pembiayaan sehingga mengharuskan PT untuk melakukan perjanjian utang piutang. Konsekuensinya ketika utang piutang tersebut tidak mampu dibayar maka perusahaan yang dipimpin oleh Notaris tersebut mengalami pailit dan telah ditetapkan melalui Putusan Pengadilan Niaga yang telah memiliki kekuatan hukum tetap. Dengan demikian status Notaris menjadi Notaris Pailit sehingga berakibat pada sanksi yang telah diatur dalam Undang-Undang Nomor 2 Tahun 2014 tentang Perubahan Atas Undang-Undang Nomor 30 Tahun 2004 Jabatan Notaris (UUJN) yaitu Notaris diberhentikan dengan tidak hormat dari jabatannya.
Penerapan Bantuan Hukum Bagi Masyarakat Kurang Mampu di Indonesia
Authors: Angga Angga , Arifin Ridwan
Published: March 2019

Bantuan hukum merupakan hak konstitusional setiap warga negara atas jaminan perlindungan dan persamaan di depan hukum, sebagai sarana pengakuan Hak Asasi Manusia (HAM). Mendapatkan bantuan hukum bagi setiap orang adalah perwujudan akses terhadap keadilan sebagai implementasi dari jaminan perlindungan hukum, dan jaminan persamaan di depan hukum. Hal ini sesuai dengan konsep bantuan hukum yang dihubungkan dengan cita-cita negara kesejahteraan.Bantuan hukum juga merupakan instrumen penting dalam Sistem Peradilan Pidana karena merupakan bagian dari perlindungan HAM bagi setiap individu, termasuk hak atas bantuan hukum. Hak atas bantuan hukum adalah salah satu hak yang terpenting yang dimiliki oleh setiap warga negara. Karena dalam setiap proses hukum, khususnya hukum pidana, para terdakwah tidak mungkin bisa untuk membela dirinya sendiri. Bagi masyarakat yang kurang mampu, pemerintah sudah menyiapkan bantuan hukum secara cuma-cuma atau gratis. Namun masih banyak masyarakat kurang mampu yang belum mengetahui hal tersebut sehingga mereka merasa tidak dibantu oleh pemerintah. Tulisan ini menjelaskan lebih jauh tentang apa itu bantuan hukum, bagaimana cara mengajukan bantuan hukum, dan siapa saja yang bisa mendapat bantuan hukum secara cuma-cuma atau gratis.
МЕТОДИКА РЕАЛІЗАЦІЇ СИСТЕМИ АВТОМАТИЗОВАНОГО КОНСТРУЮВАННЯ ТА ВИГОТОВЛЕННЯ ПРИСТОСУВАНЬ ПРИ ТЕХНОЛОГІЧНІЙ ПІДГОТОВЦІ ЛІТАКОБУДІВНОГО ВИРОБНИЦТВА В РЕЖИМІ ВІРТУАЛЬНОЇ РЕАЛЬНОСТІ
Authors: Бычков Сергей Андреевич , Читак Виталий Георгиевич
Published: March 2019

The technique of application and practical implementation of the technology of virtual reality in the technological preparation of the production of domestic civil aircraft has been developed. The technique is used to implement the assembly of parts, assemblies and accessories in the aggregate and assembly production on the example of the center section of the An-148 aircraft and the creation of technological planning of workplaces based on designed electronic models. The main provisions of the concepts of system design and manufacture of devices in the mode of virtual reality. The principles of its implementation on the basis of electronic design and technological layouts are proposed. The composition of the main components of the systems and the sequence of stages of stimulation of production technologies for ЗD, digital design and technological preparation of production are given.
A Configuração das Redes Sociais de Suporte a Pessoas com Câncer: um Olhar sob o Prisma da Informação e Comunicação em Saúde
Authors: Ribeiro Fabiana Felix , Marteleto Regina Maria
Published: March 2019

Introdução: O câncer de cabeça e pescoço engloba vários tipos de tumores. Entre eles, destacam-se o câncer de laringe e o de cavidade oral. O câncer de laringe ocupa a primeira posição e representa o segundo tipo de câncer respiratório mais comum do mundo. No Brasil, é o oitavo tipo de câncer mais incidente entre homens. Já o câncer de cavidade oral ocupa a décima quinta posição entre todos os tipos de cânceres e, no Brasil, representa o quinto mais comum. Ambos os tipos atingem principalmente homens com idade superior a 40 anos. Objetivo: Identificar como se constroem as formas de comunicação, fluxos de informação e a apropriação de conhecimentos pelos pacientes matriculados na clínica de cabeça e pescoço do Instituto Nacional de Câncer José Alencar Gomes da Silva e suas redes sociais, na perspectiva de que tais recursos são fundamentais para lidar com as mudanças e necessidades impostas pela situação de adoecimento.Método: Trata-se de um estudo de natureza qualitativa, pautado na metodologia de história oral de vida, utilizando como apoio teórico os conceitos de narrativa e redes sociais. Foram realizadas três entrevistas com pacientes em estágios diferentes de tratamento. Conclusão: O processo de informação e comunicação que se configura nas redes sociais dos pacientes é fundamental na construção de estratégias de suporte e proteção social ao longo do tratamento. Esse conhecimento torna-se fundamental na interlocução com as políticas públicas,tendo em vista a possibilidade de participação e ampliação de direitos.
Identificação do Nível de Conhecimento sobre Aspectos Nutricionais Relacionados ao Câncer em Acadêmicos de Educação Física do Iesgf
Authors: Lembeck Jarvis Duessmann , De Simas Heloise Elena , Junior Moacir Pereira
Published: March 2019

Introdução: O câncer é uma das principais causas de morte no mundo e é uma das doenças que mais cresce no Brasil. A estimativa é de que 600 mil casos novos sejam diagnosticados para o biênio 2018-2019, em cada ano. Objetivo: O presente estudo tem como objetivo avaliar o nível de conhecimento sobre aspectos nutricionais relacionados ao câncer em acadêmicos de educação física do Instituto de Ensino Superior da Grande Florianópolis. Método: Estudo do tipo descritivo de caráter quantitativo, de corte transversal, com 186 acadêmicos do curso de educação física devidamente matriculados, maiores de 18 anos e que assinaram o Termo de Consentimento Livre e Esclarecido. A caracterização da amostra foi obtida por meio da ficha de identificação, anexada ao instrumento de avaliação. Para avaliar o conhecimento nutricional, os participantes responderam à Escala de Conhecimento Nutricional, composta por 12 questões, com a pontuação máxima de14 pontos. Pontuações totais entre 0 e 6 (baixo conhecimento nutricional); entre 7 e 10 (moderado conhecimento nutricional) e acima de 10 (alto conhecimento nutricional). Resultados: O conhecimento nutricional da amostra revelou um escore total de 8,26±2,49 pontos, com mediana de 8 e moda 7. O resultado apresentado, de modo geral, foi de (57,5%) moderado conhecimento entre os estudantes, sendo que a correlação entre os pontos do instrumento e o semestre em curso foi de 0,09 (p=0,18), e a correlação de dados entre os pontos do instrumento e a idade foi de 0,07 (p=0,27). Conclusão: Em um contexto geral, os acadêmicos de educação física apresentaram moderado conhecimento nutricional sobre o câncer. Em relação aos iniciantes e concluintes, apresentou-se o resultado de moderado conhecimento sobre aspectos nutricionais relacionados ao câncer, sendo que este último apresentou melhor conhecimento. Na comparação entre sexos, houve moderado conhecimento para ambos, porém observou-se que o sexo feminino apresentou um melhor conhecimento nutricional.
Perspectives of Optimization of Technical Services and Maintenances Using Risk-Informed Decision-Making at NPPs in Ukraine
Authors: Gumenyuk D. , Demianiuk V. , Ilina A. , Shevchenko I.
Published: March 2019

In most cases, when it goes about maintenance and repair optimization, the repair concept based on technical state of equipment is considered. This article describes the approach to maintenance and repair optimization at nuclear power plants by their transfer from the outage period to unit operation at power. The analysis of maintenance and repair optimization at foreign NPPs is carried out. The U.S. experience in reducing the outage duration is described. The article presents information on the pilot maintenance and repair optimization project at Zaporizhzhya NPP unit 2. The US Department of Energy through Argonne National Laboratory provides support in the implementation of the project in Ukraine focused on maintenance optimization of safety important systems based on risk-informed configuration management. The scope of this Project involves technical engineering analyses, plant personnel training, a study of improved economic performance indicators, and development of new strategies for NPP configuration, maintenance and operation. In order to optimize plant oeration, it is necessary to analyze plant commitments and requirements using effective, unbiased engineering assessments. Plant specific Probabilistic Risk Assessment combined with other engineering analyses techniques will be used for these assessments. This article also describes the results of the analysis of the preparedness of the Ukrainian regulatory framework for the implementation of the Project on maintenance optimization. The analysis focused on the U.S. and Ukrainian regulations and documents of the IAEA and WENRA international organizations related to maintenance optimization using riskinformed management of plant configuration. Based on the comparative analysis results, the authors identified possible limitations stipulated by non-compliance of the Ukrainian nuclear and radiation safety regulatory framework with the U.S. regulatory and methodological documents used for maintenance and repair optimization at the U.S. NPPs. In particular, the overview of USA regulations leads to the conclusion that they contain exhaustive requirements for the application of maintenance using risk-informed plant configuration management at all stages of its implementation, starting with the requirements for the alternative approach to maintenance and ending with the requirements for maintenance performance monitoring. Ukrainian regulations in turn contain only general provisions and areas for potential application of risk-informed approaches in operation and inspection. It should also be noted that the U.S. maintenance optimization methodology uses criteria based on the core damage frequency and large early release frequency. However, besides core damage frequency Ukraine uses the emergency release frequency criterion that does not correspond to the definition for large early release frequency used in the U.S.
Modern Methods of Radiochemical Reprocessing of Spent Nuclear Fuel
Authors: Maltseva T. , Shyshuta А. , Lukashyn S.
Published: March 2019

The paper is devoted to the history of development and the current state of technological and scientific advances in radiochemical reprocessing of spent nuclear fuel from water-cooled power reactors. Regarding spent nuclear fuel (SNF) of NPP power reactors, long-term energy security involves adopting a version of its radiochemical treatment, conditioning and recirculation. Recycling SNF is required for the implementation of a closed fuel cycle and the re-use of regeneration products as energy reactor fuels. The basis of modern technological schemes for the reprocessing of the spent nuclear fuel is the “Purex” process, developed since the 60s in the USA. The classic approach to the use of U and Pu nuclides contained in spent nuclear fuel is to separate them from fission products, re-enrich regenerated uranium and use plutonium for the production of mixed-oxide (MOX) fuel with depleted uranium. The modern reprocessing plants are able to deal with fuel with further increase of its main characteristics without significant changes in the initial project. In order to close the fuel cycle, it is needed to add the following technological steps: (1) removal of high-level and long-lived components and minor actinides; (2) return of actinides to the technological cycle; (3) safe disposal of unused components. Each of these areas is under investigation now. Several new promising multi-cycle hydrometallurgical processes based on the joint extraction of trivalent lanthanides and minor actinides with their subsequent separation have been developed. A number of promising materials is suggested to be potential matrices for the immobilization of high-level components of radioactive wastes. To improve the compatibility of fuel processing with the environment, non-aqueous technologies are being developed, for instance, pyro-chemical methods for the reprocessing of various types of highly active fuels based on metals, oxides, carbides, or nitrides. An important scientific and technological task under investigation is transmutation of actinides. The results of international large-scale experiments on the partitioning and transmutation of fuel with various minor actinides and long-lived fission products confirm the real possibility and expediency of closing the nuclear fuel cycle.
Mid-Weighed Kinetic Parameters for Use in the Two-Group Diffusion Model of Reactor Dynamics with Fuel Based on a Mixture of Fission Isotopes
Authors: Khalimonchuk V.A.
Published: March 2019

In the model of reactor kinetics based on the description of neutron transport in the two-group diffusion approximation, the number of equations describing the change in the concentration of delayed neutron precursors depends not only on the number of groups of delayed neutrons, but also on the number of fissile isotopes present in nuclear fuel. Since each isotope is characterized by six groups of delayed neutrons, the total number of differential equations describing concentrations of delayed neutron precursors is equal to the product of the number of fissile isotopes (M) and the number of groups of delayed neutrons for each isotope (i = 6). This is true provided that the decay constant of the concentrations of delayed neutron precursors that were formed from the division by fast or thermal neutrons can be taken in the same way. In fact, there is a difference, though small, in these values for the two energy groups. Therefore, the number of the corresponding equations is twice as high. In this paper, a mathematical expression is obtained for the weighted average decay constant of delayed neutron predecessors from fission by fast and thermal neutrons in a multiplying medium with several fissile isotopes. This, together with the conventional procedure of weighing the fraction of delayed neutrons from fission by fast or thermal neutrons in a similar multiplying medium, allows the two-group diffusion model of the reactor kinetics to be limited to only six equations for the concentrations of delayed neutron precursors and thus the kinetic model of the reactor to be simplified.
Analysis of Possible Causes of NPP Emergencies to Minimize Risk of Their Occurrence
Authors: Popov O. , Іatsyshyn A. , Kovach V. , Artemchuk V. , Taraduda D. , Sobyna V. , Sokolov D. , Dement M. , Yatsyshyn T. , Matvieieva I.
Published: March 2019

The paper states that various emergencies may occur at nuclear power plants under different negative conditions. Such emergencies pose a significant risk for the natural environment, health of personnel and the public of the adjacent territories. There are examples of the major accidents at NPPs worldwide, which lead to serious radiation contamination of the environment. It is noted that one of the main tasks of the Energoatom in the sphere of emergency preparedness and civil defense in the nearest future is to improve the systems and equipment, engineering, software and hardware support of the emergency preparedness and response system dealing with NPP emergencies. The improvement of this system requires the knowledge of causation chains of emergency progression in specific conditions. Therefore, the paper is devoted to the in-depth analysis of possible causes of different emergencies at NPPs that will allow the development of new and more efficient approaches and methods of their prevention. There is a definition of emergencies and their main types. The researchers analyzed a number of references on the studies in civil defense of radiation hazardous facilities and presented that despite the implementation of technologies and automated NPP monitoring systems, the threat of potentially hazardous situations remains relevant. Besides, the most significant are the emergencies that cause radioactive and chemical contamination of the environment. The paper provides the dynamics of emergencies in Ukraine and experience of applying the IAEA Unified System for Information Exchange in Incidents and Emergencies (USIE). It describes the main operational events at Ukrainian NPPs in 2017 and presents the distribution of operational events at Ukrainian and Russian NPPs. There are safety factors considering national regulatory documents and IAEA recommendations to assess the current safety level of NPP unit and the main causes of emergencies on NPP sites. The example of SUNPP-2 shows the quantitative characteristics of internal and external impacts on its safety. Provides an example of the system for prevention and mitigation of emergencies at Ukrainian NPPs, as well as lists its main tasks.
Development of school biological education in Ukraine: retrospective and present
Authors: Novykova Nina
Published: March 2019

The necessity of introducing a new paradigm of educational and pedagogical activity in Ukraine is outlined: the accumulation of a large number of factual data in the natural sciences required new general-scientific logic-methodological approaches, which includes a systematic (system-structural) approach, therefore it is important to study the components (elements) of the system and their interaction. The system vision of wildlife has confirmed the universality, the importance of all levels of organization of the living: molecular genetic, cellular, organism (ontogenetic), populational-species, biogeocoenic-biosphere.

The methodology of the study of school biological education in the aspect of orientation of the European direction of educational development, in particular the use of synergetic, systemic-structural and holistic approaches, is considered. The methodology of pedagogy includes principles and methods of cognition in pedagogical theory and practice During the time of Ukraine's independence, the target orientation of education, its didactic support, and new methodological principles have been transformed. in the conduct of research it is necessary to consider in the relationship of philosophical methodology, psychological and pedagogical methodology and specific methodology (methodology of the topic under study).

The study of the development of school biological education as a holistic pedagogical system involves its multicomponent (target, content, procedural, gnostic-professional and analytical-productive) with new methodological approaches to its study. The school system of education should ensure the full mastery of the students of the foundations of science, the formation of a scientific picture of the world, an understanding of the need for a careful attitude to nature, man and the values that she created, skills and abilities to act in non-standard situations. The solution of these tasks is aimed at further improving the content of school education, the search for new technologies that would improve the efficiency of the educational process. The essence of levels of scientific knowledge is revealed; the holistic model of school biological education as the basis for its periodization in Ukraine during the XX - the beginning of the XXI century was proposed. The peculiarities of changes on each of the four periods and corresponding stages of the system of school biological education in the socio-economic, scientific-pedagogical and methodical aspects are analyzed. The general tendencies of school biology are revealed.
Pengaruh Lokasi dan Kualitas Pelayanan Terhadap Kepuasan Pelanggan Pada Jasa Pengiriman J & T di Muara Bulian
Authors: Mukhlis M Aziz
Published: March 2019

Bussiness world competition currently is more progressively tight. It is also perceived by  services J & T In muara bulian. J & T is demanded to understand about the factors that can influence their customer’s satisfaction. J & T have to make some improvement and innovation that can increasing their customer’s satisfaction. The research aims to analyze how the influence of service quality, and location toward customer satisfaction. Sample of the research is 81 customer and then an analysis is performed toward the obtained data by using data analysis quantitatively and qualitatively. Quantitatively analysis includes: validity and realibility test, classical assumption test, multiple regression analysis and hypothesis test through t and F test, and determination coefficient analysis (R²). Qualitative analysis is an interpretation of the obtained data within research and the result of data processing has been implemented by providing information and explanation. Data has complied validity, realibility and classical test is processed, so that those are resulting regression equation as follows: Where, Y = a + b1 X1 + b2 X2 Customer Satisfaction (Y), Service Quality variable (X1), service qualitu variable (X2), and Location variable (X3). Hyphothesis test uses t test demonstrates that the three of examined independent variables is proved significantly have a partially effect on dependent variable of Customer Satisfaction. Then, follow the F test can be recognized that the three of examined independent variables has a simultaneously effect on dependent variable of Customer Satisfaction
Pengaruh Lingkungan Kerja Terhadap Kinerja Pegawai Pada Kantor Badan Perencanaan Pembangunan Daerah Kabupaten Batang Hari
Authors: Darma Budi , Anas Azwar
Published: March 2019

This study entitled the influence of the work environment on employee performance at the Office of the Regional Development Planning Board of Batang Hari Regency. In this study will be tested how much influence the work environment on employee performance. In analyzing data, in this study using Path Analysis and t test. This study has the same population and sample of 63 people. Data retrieval is done by distributing question questionnaires. Based on the discussion it can be concluded that the influence of the work environment on performance is 34.45%. And the Work Environment has a partial and significant effect on employee performance at the Office of the Regional Development Planning Board of Batang Hari Regency.
Pengaruh Motivasi dan Kepuasan Kerja Terhadap Kinerja Pegawai Pada Dinas Pendidikan Kabupaten Tanjung Jabung Barat
Authors: Wulansari Kasiyati Yunita
Published: March 2019

The title raised in this study is the Effect of Job Motivation and Satisfaction on Employee Performance at the Education Office of West Tanjung Jabung Regency. This study aims to determine the effect of Motivation and Job Satisfaction on Employee Performance at the Tanjung Jabung Barat District Education Office. Testing is done using multiple linear regression analysis. Hypothesis testing is done by using t test and F test. The magnitude of the effect is known through testing the coefficient of determination. Based on the discussion it can be concluded that the effect of Motivation (X1) and Job Satisfaction (X2) together on Performance (Y) is 13.275%. In the t test, the effect of Motivation (X1) and Job Satisfaction (X2) has a partial effect on Performance (Y). in the F test, Motivation (X1) and Job Satisfaction (X2) have a simultaneous influence on performance (Y).
Faktor-Faktor yang Mempengaruh Siswa SLTA dalam Memilih Perguruan Tinggi di Kabupaten Batang Hari (Studi Kasus Pada STAI dan STIE-GK Muara Bulian)
Authors: Fithoni Ahmad , Priyatna Atang
Published: March 2019

This study aims to find out and analyze the factors that influence the decision of high school students in choosing universities in Batang Hari Regency. The object of research is STAI and STIE-GK Muara Bulian. This research is descriptive quantitative with the number of respondents as many as 75 students for each college which is the object of research registered in the 2018/2019 academic year. This type of research is descriptive qualitative research that aims to determine whether there is an influence or relationship between two or more variables with the analysis tools used include Partial Test (t test), Simultaneous Test (Test F), and Determination Coefficient Test (R2). The results of the study show that the independent variables include Study Program variables (X1), Accreditation Status (X2), Facilities (X3) and Costs (X4) on Student Decisions (Y). For STAI Muara Bulian, only Accreditation variables have a partial influence on student decisions and even then it is not significant. For STIE-GK Muara Bulian, it is known that all independent variables have a partial and significant influence on the decisions of high school students to enter. Judging from the F test, it is known that the independent variables simultaneously have an influence on the dependent variable in having a college in Batang Hari Regency. The test results of the coefficient of determination for STAI Muara Bulian amounted to 88.9% and for STIE-GK Muara Bulian at 95.3% while the remaining respectively 11.1% and 4.7% were influenced by other factors not included in the research variable.
CARACTERIZAÇÃO DAS CONDIÇÕES CLIMÁTICAS DE PAU DOS FERROS-RN
Authors: Gurgel Amanda Lopes , Medeiros Jacimária Fonseca de
Published: March 2019

O Semiárido Brasileiro possui características climáticas particulares, caracterizadas pelas elevadas temperaturas, escassez e irregularidade das precipitações pluviométricas, baixos níveis de umidade e elevadas taxas de evaporação. Inserido neste contexto, o município de Pau dos Ferros - RN se configura como objeto de estudo desta pesquisa, tendo como escopo principal realizar uma análise das condições climáticas locais para o espaço-temporal de 30 anos, período de 1973 a 2002. O arcabouço metodológico utilizado nesta pesquisa se encontra ancorado em Medeiros (2016). Os dados de precipitação foram adquiridos na EMPARN e os de temperatura foram estimados no software Estima-T. Esses, foram fundamentais para a análise do comportamento dos elementos climáticos (temperatura e precipitação), e posterior, aplicação do balanço hídrico climatológico, segundo proposta de Thornthwaite e Mather (1955). Por meio destes, tornaram-se possíveis evidenciar o déficit hídrico no município na maior parte do ano, em virtude de taxa de evaporação superior ao acumulado pluviométrico. Os dados gerados pelo balanço hídrico subsidiaram a definição da tipologia climática, sendo subúmido seco, com alto índice efetivo de umidade, subtipo d, com características de pequeno ou nenhum excedente hídrico. Assim sua fórmula climática se classifica como ‘C¹ d A’, ou seja, Megatérmico Subúmido Seco com pequeno ou nenhum excedente de água.

Palavras-chave: Análise climática. Pau dos Ferros-RN. Tipologia climática.
QUALIDADE DAS ÁGUAS SUBTERRÂNEAS DA CIDADE DE PAU DOS FERROS-RN
Authors: Pereira de Araujo Caio Sergio , Bezerra Joel Medeiros
Published: March 2019

As águas subterrâneas no município de Pau dos Ferros, a cada dia são mais exploradas para o abastecimento residencial, como também para o comércio local e abastecimento animal. A demanda por água, devido a longa estiagem que assola, gera uma preocupação sobre o futuro dos recursos hídricos. Entretanto, a população faz sua exploração de maneira desordenada sem se preocupar com a quantidade e a qualidade dessas águas, visto que, a recarga desses mananciais não vem acontecendo devido à estiagem de chuvas e o aumento da concentração de minerais e outros sólidos nos poços de captação, os quais podem limitar seus múltiplos usos e causar doenças futuras a população. Desse modo, este trabalho objetivou avaliar a qualidade das águas subterrâneas na cidade de Pau dos Ferros-RN, em que foram efetuadas coletas de água de 18 poços tubulares na área urbana do município, sendo analisados parâmetros físicos e químicos em laboratório da Universidade Federal Rural do Semiárido. Os resultados das análises mostraram a ocorrência de poços com altos teores de cálcio e magnésio, aumentando assim a condutividade elétrica, a dureza da água e consequentemente deixando-a salobra. Quanto a distribuição espacial, o poço 12 localizado no bairro São Judas Tadeu apresentou os níveis mais altos de sais de cálcio e magnésio. Os órgãos responsáveis pela gestão das águas subterrâneas deveriam promover políticas de manejo e conscientização desses recursos, a fim de promover o uso racional destas.

Palavras-chave: Estiagem. Mananciais. Recursos hídricos.