bluuebunny/crossref_metadata_2025 huggingface dataset:
A Plug and Play Transparent Communication Layer for Cloud Robotics Architectures
Authors: Sorrentino Alessandra , Cavallo Filippo , Fiorini Laura
Published: March 2020

The cloud robotics paradigm aims at enhancing the abilities of robots by using cloud services, but it still poses several challenges in the research community. Most of the current literature focuses on how to enrich specific robotic capabilities, overlooking how to effectively establish communication between the two fields. Our work proposes a “plug-and-play” solution to bridge the communication gap between cloud and robotic applications. The proposed solution is designed based on the mature WebSocket technology and it can be extended to any ROS-based robotic platform. The main contributions of this work are the definition of a reliable autoconnection/autoconfiguration mechanism as well as to outline a scalable communication layer that allows the effective control of multiple robots from multiple users. The “plug-and-play” solution was evaluated in both simulated and real scenarios. In the first case, the presence of users and robots was simulated with Robot Operating System (ROS) nodes running on five machines. In the real scenario, three non-expert users teleoperated, simultaneously, three remote robots by using the proposed communication layer with different networking protocols. Results confirmed the reliability at different levels: at startup (success_rate = 100%); during high-rate communications (message_lost = 0%); in performing open-loop spiral trajectories with enhancement, with respect to similar works; and in the quality of simultaneous teleoperations.
The role of Interferometric Synthetic Aperture Radar in Detecting, Mapping, Monitoring, and Modelling the Volcanic Activity of Piton de la Fournaise, La Réunion: A Review
Authors: Richter Nicole , Froger Jean-Luc
Published: March 2020

Synthetic Aperture Radar (SAR) remote sensing plays a significant role in volcano monitoring despite the measurements’ non real-time nature. The technique’s capability of imaging the spatial extent of ground motion has especially helped to shed light on the location, shape, and dynamics of subsurface magmatic storage and transport as well as the overall state of activity of volcanoes worldwide. A variety of different deformation phenomena are observed at exceptionally active and frequently erupting volcanoes, like Piton de la Fournaise on La Réunion Island. Those offer a powerful means of investigating related geophysical source processes and offer new insights into an active volcano’s edifice architecture, stability, and eruptive behavior. Since 1998, Interferometric Synthetic Aperture Radar (InSAR) has been playing an increasingly important role in developing our present understanding of the Piton de la Fournaise volcanic system. We here collect the most significant scientific results, identify limitations, and summarize the lessons learned from exploring the rich Piton de la Fournaise SAR data archive over the past ~20 years. For instance, the technique has delivered first evidence of the previously long suspected mobility of the volcano’s unsupported eastern flank, and it is especially useful for detecting displacements related to eruptions that occur far away from the central cone, where Global Navigation Satellite System (GNSS) stations are sparse. However, superimposed deformation processes, dense vegetation along the volcano’s lower eastern flank, and turbulent atmospheric phase contributions make Piton de la Fournaise a challenging target for applying InSAR. Multitemporal InSAR approaches that have the potential to overcome some of these limitations suffer from frequent eruptions that cause the replacement of scatterers. With increasing data acquisition rates, multisensor complementarity, and advanced processing techniques that resourcefully handle large data repositories, InSAR is progressively evolving into a near-real-time, complementary, operational volcano monitoring tool. We therefore emphasize the importance of InSAR at highly active and well-monitored volcanoes such as Mount Etna, Italy, Kīlauea Volcano, Hawai’i, and Piton de la Fournaise, La Réunion.
Dynamic Monitoring of a Mid-Rise Building by Real-Aperture Radar Interferometer: Advantages and Limitations
Authors: Alva Rodrigo E. , Pujades Luis G. , González-Drigo Ramón , Luzi Guido , Caselles Oriol , Pinzón Luis A.
Published: March 2020

In this paper, remote and in situ techniques to estimate the dynamic response of a building to ambient vibration are reported: data acquired through a real-aperture radar (RAR) interferometer and conventional accelerometers are analyzed. A five-story reinforced concrete housing building, which was damaged during the May 11th 2011 Lorca (Spain) earthquake, is used as a case study. The building was monitored using both types of instruments. The dynamic properties of the building are estimated first taking acceleration measurements using a set of 10 high-precision accelerometers installed on the roof of the building. Further, the displacement–time histories, recorded with the RAR device pointing to a corner of the building, are analyzed. Then, the ability and shortcomings of RAR measurements to deal with the fundamental frequencies of vibration of the structure are investigated. The advantages and limitations of from-inside (accelerometric) and from-outside (RAR) measurements are highlighted and discussed. A relevant conclusion is that, after strong earthquakes, RAR may be an interesting and useful tool, as it allows surveying the structural response of mid-rise buildings remotely, without the need to enter the structures, which may be dangerous for inspectors or technicians in cases of severely damaged buildings. Given that the instrumented building suffered significant damage, the ability of these kinds of measurements to detect damage is also discussed.
Satellite-Derived PM2.5 Composition and Its Differential Effect on Children’s Lung Function
Authors: Chau Khang , Franklin Meredith , Gauderman W. James
Published: March 2020

Studies of the association between air pollution and children’s health typically rely on fixed-site monitors to determine exposures, which have spatial and temporal limitations. Satellite observations of aerosols provide the coverage that fixed-site monitors lack, enabling more refined exposure assessments. Using aerosol optical depth (AOD) data from the Multiangle Imaging SpectroRadiometer (MISR) instrument, we predicted fine particulate matter, PM 2.5 , and PM 2.5 speciation concentrations and linked them to the residential locations of 1206 children enrolled in the Southern California Children’s Health Study. We fitted mixed-effects models to examine the relationship between the MISR-derived exposure estimates and lung function, measured as forced expiratory volume in 1 second (FEV 1 ) and forced vital capacity (FVC), adjusting for study community and biological factors. Gradient Boosting and Support Vector Machines showed excellent predictive performance for PM 2.5 (test R 2 = 0.68 ) and its chemical components (test R 2 = –0.71). In single-pollutant models, FEV 1 decreased by 131 mL (95% CI: − 232 , − 35 ) per 10.7-µg/m 3 increase in PM 2.5 , by 158 mL (95% CI: − 273 , − 43 ) per 1.2-µg/m 3 in sulfates (SO 4 2 − ), and by 177 mL (95% CI: − 306 , − 56 ) per 1.6-µg/m 3 increase in dust; FVC decreased by 175 mL (95% CI: − 310 , − 29 ) per 1.2-µg/m 3 increase in SO 4 2 − and by 212 mL (95% CI: − 391 , − 28 ) per 2.5-µg/m 3 increase in nitrates (NO 3 − ). These results demonstrate that satellite observations can strengthen epidemiological studies investigating air pollution health effects by providing spatially and temporally resolved exposure estimates.
Trends in the Stability of Antarctic Coastal Polynyas and the Role of Topographic Forcing Factors
Authors: Jiang Liyuan , Ma Yong , Chen Fu , Liu Jianbo , Yao Wutao , Qiu Yubao , Zhang Shuyan
Published: March 2020

Polynyas are an important factor in the Antarctic and Arctic climate, and their changes are related to the ecosystems in the polar regions. The phenomenon of polynyas is influenced by the combination of inherent persistence and dynamic factors. The dynamics of polynyas are greatly affected by temporal dynamical factors, and it is difficult to objectively reflect the internal characteristics of their formation. Separating the two factors effectively is necessary in order to explore their essence. The Special Sensor Microwave/Imager (SSM/I) passive microwave sensor has been making observations of Antarctica for more than 20 years, but it is difficult for existing current sea ice concentration (SIC) products to objectively reflect how the inherent persistence factors affect the formation of polynyas. In this paper, we proposed a long-term multiple spatial smoothing method to remove the influence of dynamic factors and obtain stable annual SIC products. A halo located on the border of areas of low and high ice concentration around the Antarctic coast, which has a strong similarity with the local seabed in outline, was found using the spatially smoothed SIC products and seabed. The relationship of the polynya location to the wind and topography is a long-understood relationship; here, we quantify that where there is an abrupt slope and wind transitions, new polynyas are best generated. A combination of image expansion and threshold segmentation was used to extract the extent of sea ice and coastal polynyas. The adjusted record of changes in the extent of coastal polynyas and sea ice in the Southern Ocean indicate that there is a negative correlation between them.
“If I’m Here, It’s Because I Do Not Have Anyone”: Social Support for the Biological Family during the Foster Care Process
Authors: Vaquero Eduard , Balsells M. Àngels , Ponce Carmen , Urrea Aida , Navajas Alicia
Published: March 2020

Social support is a crucial element for families in vulnerable situations, especially for those with children in foster care processes. This support is key to the acceptance of the protection measure in the initial moments and to laying the foundations for collaboration towards reunification. However, the social support of these families is limited, and families’ use of support elements is strongly related to their attitude towards them. The aims of this article were to identify the types and characteristics of social support and to analyze what elements influence families’ attitudes towards these supports. The qualitative study research was carried out in Spain through focus groups and interviews with 135 participants: 63 professionals from child protection services, 42 parents, and 30 children and adolescents who had been in foster care measures. Results show the diversity of social support resources available to families and demonstrate that families make unequal use of such resources depending on factors such as their experiences in the process of formalization and communication of the protection measure or their predisposition to receive support, among others. The important role played by social support resources in the promotion of factors that allow for successful reception and reunification is highlighted.
Simulation-Based Electric Vehicle Sustainable Routing with Time-Dependent Stochastic Information
Authors: Li Xinran , Kan Haoxuan , Hua Xuedong , Wang Wei
Published: March 2020

We propose a routing method for electric vehicles that finds a route with minimal expected travel time in time-dependent stochastic networks. The method first estimates whether the vehicle can reach the destination with the current battery level and selects potential reasonable charging stations if needed. Then, the route-search problem is formulated as a shortest path problem with time-dependent stochastic disruptions, using a Markov decision process. The shortest path problem is solved by an approximate dynamic programming algorithm to improve calculation efficiency in complex networks. Several simulation cases and a scenario-based example are given to prove the validity of the method.
Plant Layout Optimization for Chemical Industry Considering Inner Frame Structure Design
Authors: Xu Siyu , Wang Yufei , Feng Xiao
Published: March 2020

Plant layout design is a complex task requiring a wealth of engineering experience. A well-designed layout can extraordinarily reduce various costs, so layout study is of great value. To promote the research depth, plenty of considerations have been taken. However, an actual plant may have several frames and how to distribute facilities and determine the location of them in the different frames has not been well studied. In this work, frames are set as a special kind of inner structure and are added into the model to assign facilities into several blocks. A quantitative method for assigning facilities is proposed to let the number of cross-frame connections be minimized. After allocating the facilities into several blocks, each frame is optimized to obtain initial frame results. With designer decisions and cross-frame flow information, the relative locations of frames are determined and then the internal frame layouts are optimized again to reach the coupling optimization between frame and plant layout. Minimizing the total cost involving investment and operating costs is set to be the objective. In the case study, a plant with 138 facilities and 247 material connections is studied. All the facilities are assigned into four frames, and only 17 connections are left to be cross-frame ones. Through the two optimizations of each frame, the length of cross-frame connections reduces by 582.7 m, and the total cost decreases by 4.7 × 105 ¥/a. Through these steps, the idea of frame is successfully applied and the effectiveness of the proposed methodology is proved.
The Formation Mechanism of Consumer Perceived Corporate Social Responsibility Authenticity: An Empirical Study of Chinese Consumers
Authors: Yu Jing , Jiang Changjun , Zhuang Xiaohong , Na Sanggyun , Cui Zongmin
Published: March 2020

Consumer Perceived Corporate Social Responsibility Authenticity (CPCSRA) belongs to the field of micro Corporate Social Responsibility (CSR) research. In general, understanding the formation mechanism of CPCSRA could make it better able to play its role in several ways. Firstly, most previous studies do not empirically consider a key factor, i.e., the consumer perceived senior managers’ involvement. We add this key factor into the independent variables of our formation mechanism. Secondly, most previous empirical research studies the relevant factors of consumer perceived CSR commitment as a whole. We study these relevant factors separately instead. Thirdly, we simultaneously choose the consumer perceived strategy-driven motive and consumer perceived value-driven motive as the mediating variables of our formation mechanism. Based on the above innovations, we comprehensively and systematically study the formation mechanism of CPCSRA. We use structural equation modeling to study the formation mechanism. For the convenience of data collection, our data are all from Chinese consumers. The study results show that three independent variables can directly affect CPCSRA. The three independent variables are consumer perceived level of invested resources, consumer perceived CSR efforts matching company and consumer perceived senior managers’ involvement. Consumer perceived senior managers’ involvement has the greatest effect. The two variables consumer perceived strategy-driven motive and consumer perceived value-driven motive play partial mediating effects on the relationship between independent variables and CPCSRA. Based on our empirical research, we put forward some feasible suggestions for company managers to increase company sustainability in market competition by promoting the formation of CPCSRA.
Implementation of Automated Baby Monitoring: CCBeBe
Authors: Choi Soohyun , Yun Songho , Ahn Byeongtae
Published: March 2020

An automated baby monitoring service CCBeBe (CCtv Bebe) monitors infants’ lying posture and crying based on AI and provides parents-to-baby video streaming and voice transmission. Besides, parents can get a three-minute daily video diary made by detecting the baby’s emotion such as happiness. These main features are based on OpenPose, EfficientNet, WebRTC, and Facial-Expression-Recognition.Pytorch. The service is integrated into an Android application and works on two paired smartphones, with lowered hardware dependence.
On Applying Machine Learning and Simulative Approaches to Railway Asset Management: The Earthworks and Track Circuits Case Studies
Authors: Consilvio Alice , Solís-Hernández José , Jiménez-Redondo Noemi , Sanetti Paolo , Papa Federico , Mingolarra-Garaizar Iñigo
Published: March 2020

The objective of this study is to show the applicability of machine learning and simulative approaches to the development of decision support systems for railway asset management. These techniques are applied within the generic framework developed and tested within the In2Smart project. The framework is composed by different building blocks, in order to show the complete process from data collection and knowledge extraction to the real-world decisions. The application of the framework to two different real-world case studies is described: the first case study deals with strategic earthworks asset management, while the second case study considers the tactical and operational planning of track circuits’ maintenance. Although different methodologies are applied and different planning levels are considered, both the case studies follow the same general framework, demonstrating the generality of the approach. The potentiality of combining machine learning techniques with simulative approaches to replicate real processes is shown, evaluating the key performance indicators employed within the considered asset management process. Finally, the results of the validation are reported as well as the developed human–machine interfaces for output visualization.
Soil Quality and Heavy Metal Pollution Assessment of Iron Ore Mines in Nizna Slana (Slovakia)
Authors: Fazekašová Danica , Fazekaš Juraj
Published: March 2020

Mining activities have resulted in the existence of dumps, which generally present a perpetual danger of moving and transforming toxic elements. The experimental study was carried out in Nizna Slana (Slovakia) where the main source of emission was the iron-ore mining–processing factory focused on siderite mining. Siderit from Nizna Slana is highly ferrous with an increased level of the Mn content. Among the undesirable impurities on the deposit are mainly As, S, Pb, and Zn. According to the environmental regionalization of the Slovak Republic, the surveyed area represents a region with a slightly disturbed environment. The BIOLOG® Eco plates method was used for ecotoxicological evaluation of contaminated soils, where soil enzymes (acidic and alkaline phosphatase and urease) were also monitored in soils and soil contamination was evaluated according to Hakanson (1980). Based on the results obtained, it can be concluded that the content of Hg, Cd, Cr, Cu, As, Fe, Mn, and Mg is above the toxicity level. As, Fe, Mn, and Mg are the most serious pollutants in the area under investigation, and their pronounced excess indicates contamination, where harmfulness and toxicity can be expected. Based on the evaluation of the contamination factor and the degree of contamination, the soils in the emission field of old mining works are very highly to slightly contaminated with heavy metals. The experimental results in the real environment showed that the activity of soil enzymes showed considerable differences, and, regarding the functional diversity of soil microorganisms, we have not seen significant spatial variability.
Ecological Suitability of Island Development Based on Ecosystem Services Value, Biocapacity and Ecological Footprint: A Case Study of Pingtan Island, Fujian, China
Authors: Zheng Weiheng , Cai Feng , Chen Shenliang , Zhu Jun , Qi Hongshuai , Zhao Shaohua , Liu Jianhui
Published: March 2020

The ecological environment and resource endowment of an island are more vulnerable compared to the mainland, and special assessment and measurement of the ecological suitability for development are significant. Pingtan Island (Fujian, China) was taken as a case study. Changes in ecosystem services value and the profit-and-loss balance between ecological footprint and biocapacity were assessed using land use/cover changes based on remote-sensing images taken in 2009, 2014 and 2017, and the ecological suitability of development was measured. Results show that island development led to a decrease in the ecosystem services value and an increase in ecological footprint and biocapacity. The key ecological factors restricting the scale of island development are topography, vegetation with special functions and freshwater. Biocapacity of islands can increase not only by changing from lower-yield land types to higher-yield construction land types but also by external investment. A new measurement framework was proposed that simply and clearly reveals the ecological suitability of island development and the underlying key constraints.
A Method to Estimate URT Passenger Spatial-Temporal Trajectory with Smart Card Data and Train Schedules
Authors: Yang Taoyuan , Zhao Peng , Yao Xiangming
Published: March 2020

Precise estimation of passenger spatial-temporal trajectory is the basis for urban rail transit (URT) passenger flow assignment and ticket fare clearing. Inspired by the correlation between passenger tap-in/out time and train schedules, we present a method to estimate URT passenger spatial-temporal trajectory. First, we classify passengers into four types according to the number of their routes and transfers. Subsequently, based on the characteristic that passengers tap-out in batches at each station, the K-means algorithm is used to assign passengers to trains. Then, we acquire passenger access, egress, and transfer time distribution, which are used to give a probability estimation of passenger trajectories. Finally, in a multi-route case of the Beijing Subway, this method presents an estimation result with 91.2% of the passengers choosing the same route in two consecutive days, and the difference of route choice ratio in these two days is 3.8%. Our method has high accuracy and provides a new method for passenger microcosmic behavior research.
Structural Insight into Paramyxovirus and Pneumovirus Entry Inhibition
Authors: Aggarwal Megha , Plemper Richard K
Published: March 2020

Paramyxoviruses and pneumoviruses infect cells through fusion (F) protein-mediated merger of the viral envelope with target membranes. Members of these families include a range of major human and animal pathogens, such as respiratory syncytial virus (RSV), measles virus (MeV), human parainfluenza viruses (HPIVs), and highly pathogenic Nipah virus (NiV). High-resolution F protein structures in both the metastable pre- and the postfusion conformation have been solved for several members of the families and a number of F-targeting entry inhibitors have progressed to advanced development or clinical testing. However, small-molecule RSV entry inhibitors have overall disappointed in clinical trials and viral resistance developed rapidly in experimental settings and patients, raising the question of whether the available structural information may provide a path to counteract viral escape through proactive inhibitor engineering. This article will summarize current mechanistic insight into F-mediated membrane fusion and examine the contribution of structural information to the development of small-molecule F inhibitors. Implications are outlined for future drug target selection and rational drug engineering strategies.
Fluorescence Microscopy of the HIV-1 Envelope
Authors: Carravilla Pablo , Nieva José L. , Eggeling Christian
Published: March 2020

Human immunodeficiency virus (HIV) infection constitutes a major health and social issue worldwide. HIV infects cells by fusing its envelope with the target cell plasma membrane. This process is mediated by the viral Env glycoprotein and depends on the envelope lipid composition. Fluorescent microscopy has been employed to investigate the envelope properties, and the processes of viral assembly and fusion, but the application of this technique to the study of HIV is still limited by a number of factors, such as the small size of HIV virions or the difficulty to label the envelope components. Here, we review fluorescence imaging studies of the envelope lipids and proteins, focusing on labelling strategies and model systems.
Antiviral Activity of Benzavir-2 against Emerging Flaviviruses
Authors: Gwon Yong-Dae , Strand Mårten , Lindqvist Richard , Nilsson Emma , Saleeb Michael , Elofsson Mikael , Överby Anna K. , Evander Magnus
Published: March 2020

Most flaviviruses are arthropod-borne viruses, transmitted by either ticks or mosquitoes, and cause morbidity and mortality worldwide. They are endemic in many countries and have recently emerged in new regions, such as the Zika virus (ZIKV) in South-and Central America, the West Nile virus (WNV) in North America, and the Yellow fever virus (YFV) in Brazil and many African countries, highlighting the need for preparedness. Currently, there are no antiviral drugs available to treat flavivirus infections. We have previously discovered a broad-spectrum antiviral compound, benzavir-2, with potent antiviral activity against both DNA- and RNA-viruses. Our purpose was to investigate the inhibitory activity of benzavir-2 against flaviviruses. We used a ZIKV ZsGreen-expressing vector, two lineages of wild-type ZIKV, and other medically important flaviviruses. Benzavir-2 inhibited ZIKV derived reporter gene expression with an EC50 value of 0.8 ± 0.1 µM. Furthermore, ZIKV plaque formation, progeny virus production, and viral RNA expression were strongly inhibited. In addition, 2.5 µM of benzavir-2 reduced infection in vitro in three to five orders of magnitude for five other flaviviruses: WNV, YFV, the tick-borne encephalitis virus, Japanese encephalitis virus, and dengue virus. In conclusion, benzavir-2 was a potent inhibitor of flavivirus infection, which supported the broad-spectrum antiviral activity of benzavir-2.
International Migration & Economic Development: The Case of EU Countries
Authors: Tolmacheva Svetlana V.
Published: March 2020

The globalization of the modern world strengthens the role of migration flows in the socio-economic development of countries and regions. The European Union, and Italy in particular, are among the main centers attracting migrants due to their geopolitical transit position and relatively favorable environment. The consequences of the explosive growth in migration flows are ambiguous. To clarify the direction and power of such effects, we perform correlation and regression analysis according to a number of parameters. The paper presents relevant data on the demographic and socio-economic situation in Italy for 2001–2017. In the literature review section, we examine the substance of international migration and identify the factors affecting the trends in economic dynamics as well as changes in migration flows. The research results confirm that the most significant determinants are employment, the GDP growth rate and the labor cost index. The study also finds that there is a positive correlation between GDP growth and inflow of remittances. The empirical data provided indicate the coherence between migration and particular macroeconomic indicators. A comprehensive analysis of the factors presents a promising pathway for improving migration policy.
Reduced hardware costs with software and hardware implementation of digital methods multistage discrete Fourier transform on programmable logic devices
Authors: Burova Adeliya Yu. , Ryapukhin Anatoly V. , Muntyan Alexandra R.
Published: March 2020

Let us consider questions, which are connected to the research of terms of hardware and software implementation digital signal processing (DSP) methods. Theoretical basis of this research are methods of non-recursive difference of digital filtration with integer difference coefficients different orders of difference and methods of multistage discrete Fourier transform (DFT) based on such digital filtration. The purpose of the study is the research and formalization of necessary and sufficient condition of lowering hardware costs in hardware and software implementation of methods multistage DFT of digital signals on programmable logic devices (PLD). For reaching the research goal there are used methods of direct search and comparative analysis of results of such realization of methods of multi-stage DFT of digital multi-band signals, while filtering these signals, which are based on their non-recursive difference digital filtering with integer difference values coefficients and different orders of magnitude of difference. There are described abilities and specialties of PLD, which are built using architecture of a coarse-grained or fine-grained architecture or using combined architecture, which connects the convenience of implementing digital processing algorithms signals on the basis of tables of code conversion and reconfigurable memory modules. It is clear that a necessary and sufficient condition of lowering hardware costs in terms of hardware and software realization of methods for multi-stage DFT of digital signals on PLD is the triviality of meanings of integer difference coefficients of a non-recursive difference digital high difference orders’ filtration, which ensure this information. There is mentioned a formula, which allows making such condition. The practical significance of the research results consists of defining the necessary and sufficient condition of lowering hardware costs in terms of hardware and software implementation on PLD methods of multi-stage DFT signals based on their non-recursive digital difference filtering with integer values differential coefficients of various orders of magnitude difference. The novelty of research results lies in formalization of this condition. The reliability of the research results confirms their compliance with the results of well-known developments of DSP methods.
Gender socialization of students with disabilities: Ukrainian practicies
Authors: Kravchenko Oksana , Oksom Pavlo , Voitovska Alla , Albul Iryna
Published: March 2020

The aim of the article is to analyze the process of gender socialization of students with disabilities. We used a comparative analysis method and method of generalization in the research process. The logic of our study involved organizing and conducting a survey of students with disabilities. The state of gender socialization of students with disabilities in six institutions of higher education of Ukraine is investigated. The social and pedagogical conditions for the formation of gender socialization of students with disabilities are substantiated. The importance of creating a gender sensitive university environment based on the idea of gender equality has been proved. The basic elements that determine the level of gender sensitivity of a higher education institution are considered. The expediency of creating self-help centers for students with disabilities is substantiated. The essence of teachers and students motivation to cooperate in an inclusive environment in the context of gender socialization is highlighted. Positive impact of students with disabilities involvement in active forms of student and out-of-class student activity has been established. It is proved that the experience of students with special educational needs is not gender-neutral, because boys and girls deal with different realities that shape the understanding of disability.
RESULTS OF INTRALESIONAL TRIAMCINOLONE ACETONIDE FOR CHALAZION TREATMENT
Authors: Nguyen Thi Thu , Vo Viet Hien , Do Thi Em
Published: March 2020

The study use intralesional triamcinolone acetonide injection proceduce for chalazion treatment.1. Objectives: To evaluate results of intralesional triamcinolone acetonide injection for chalazion treatment. 2. Method: This noncomparative prospective interventional trial included 72 chalazions of 61 patients. 3. Results: 61 patients (72 chalazions) with 19 males (31.1%) và 42 females (68.9%), the mean age was 24 ± 9,78 years. 31.1% patients was the first time chalazion and 68.9% patients was more than one times chalazion including 78.6% patients was recurrent at the first position and 21.4% patients occur at new position. 72 chalazions with 16 (22.2%) chalazions was treated before and 56 (77.8%) chalazions wasn’t done that. 72 chalazions with 49 chalazions (68.1%) are local in upper eyelid and 23 chalazions (31.9%) are local in lower eyelid. The mean of chalazion diameter is 6.99 ± 3.03mm. Intralesional triamcinolone acetonide is injected to treat 72 chalazions with 16 (22.2%) chalazions are injected through the route of skin and 56 (77.8%) chalazions are injected through the route of conjunctiva. After 2 weeks follow-up, the success rate was 93.1% and 6.9% failed. 4. Conclusion: intralesional triamcinolone acetonide injection for chalazion treatment is really effective. Key words: chalazion, intralesional triamcinolone acetonide.
THE COMBINATION OF T WAVE ALTERNANS AND HEART RATE VARIABILITY TO PROGNOSIS HEART FAILURE
Authors: Hoang Anh Tien
Published: March 2020

Objectives: In reccent decades of research now link TWA with inducible and spontaneous clinical ventricular arrhythmias. This bench-tobedside foundation makes TWA a very plausible index of worsen of clinical status. Also with the heart rate variability. We research this study with 2 targets: 1. Prognosis value of TWA and HRV in heart failure. 2. Prognosis value of the combination of TWA and HRV in heart failure. Methods: Prospective study: 82 chronic heart failure patients were admitted to hospital from 2010 May to 2011 May and 50 healthy people were done treadmill test to caculate TWA, ECG, Holter ECG, echocardiography. Results: The combination of TWA and HRV to prognosic the worsen clinical status have the highest prognosis value with OR=102.13 (p<0.001) sensitivity: 80.49%, specificity: 98%, positive predict value: 98.51%, negative predict value: 75.38%. The combination of TWA and HRV to prognosic the ventricular arrythmia have the highest prognosis value with OR=46.25 (p<0.001) sensitivity: 83.33%, specificity: 90.24%, positive predict value: 89.74%, negative predict value: 84.09%. Conclusions: We should combine TWA and HRV in clinical to prognose heart failure patients.
LOW RESPONSE TO CONTROLLED OVARIAN STIMULATION
Authors: Cao Ngoc Thanh , Le Minh Tam , Nguyen Vu Quoc Huy
Published: March 2020

In routine assisted reproductive technologies (ART), controlled ovarian stimulation is recommended to overcome the selection of one dominant follicle and to allow the growth of a cohort of follicles. This management aims to increase the number of oocytes and therefore the number of embryos leads to increasing the chance of transferring the high quality embryos. However, there is still about 10% of ART cycles face to low response with controlled ovarian stimulation which is one of the major challenges to clinical endocrinologists. Poor responders have a higher incidence of cycle cancellation, lower fertilization, and lower implantation rates. So far, there is no universally accepted definition of poor responders, with many different criteria in static tests and dynamic tests as well as different cutoff levels used to predict the ovarian response. That is the reason why the review studies show limited data of highly agreed diagnosis, management and prediction of the condition. After trying some different stimulation protocols, oocyte donation can be a choice and more research in basic medicine should be carried out to understand the mechanism underlying this condition
LONG - TERM RESULTS FROM CURABLE GASTRECTOMY AND D2, D3 LYMPHADENECTOMY IN GASTRIC CANCER TREATMENT
Authors: Le Manh Ha , Nguyen Quang Bo
Published: March 2020

Objectives: Evaluation of pathological characteristics, motality rate and five-year survival rate from curable gastrectomy and D2, D3 lymphadenectomy in gastric cancer at Hue Centre Hospital. Materials and methods: Consist of 119 patients underwent curable gastrectomy and D2, D3 lymphadenectomy from May 2005 to May 2012. Results: Age: average 56.2 ± 11.8 (19-81), male/female 1.83/1. Distal subtotal gastrectomy 88.24%, total gastrectomy 7.56%, proximal subtotal gastrectomy 4.2% Lymphadenectomy: D2 62.18%, D3 37.82%. TNM classification: first stage 4.20%, second stage 29.41%, third stage 61.34% và fourth stage 5.04%. Intraoperative splenic rupture was the most common 5.88%, overall five-year survival rate 28.8%, overall D2 five-year survival rate 47.9%; overall D3 five-year survival rate 63.1% (not significant with p = 0.1137) and non relatively operative motality. Conclusion: Curable gastrectomy and D2, D3 lymphadenectomy in gastric cancer is safety, five-year survival rate is long-term, and oncologically effective procedure. Keywords: Gastric cancer, Gastrectomy, D2, D3 Lymphadenectomy.
Key words: Gastric cancer, Gastrectomy, D2, D3 Lymphadenectomy
PREDICTION OF TYPE 2 DIABETES MELLITUS BY FINDRISC ON PRE-DIABETES PATIENTS OVER 45 YEARS OLD
Authors: Nguyen Van Vy Hau , Nguyen Hai Thuy
Published: March 2020

Objectives: To predict the risk of type 2 diabetes mellitus (T2DM) in ten years by applying FINDRISC. Methods: 131 patients were diagnosed pre-diabetes according to the ADA (2010) criteria using fasting plasma glucose, 2h after 75g oral glucose load and/or HbA1c. FINDRISC includes eight parameters: age, abdominal obesity, waist circumference, family history of diabetes, physical activity, history of increased glucose and using of anti-hypertensive medications and eating habit of vegetables fruits or berries. Results: In the eight element of FINDRISC, BMI and waist circumference, family history of diabetes, history of hypertension and antihypertensive drug use are risk factors are most important. The area under the curve order is 0.912; 0.879; 0.819; 0.720 and 0.664 respectively. Application FINDRISC- South Asian we recorded the optimal cut points 9 points (Se = 0.61, Sp = 0.85, p <0.001) to detect pre-diabetes and 15 points (Se = 1.00 and Sp=0.91, p< 0.0001) to detect diabetes. Risk of diabetes in 10 years by using FINDRISC-Asian scale is higher than using FINDRISC- European scale: 7.68% vs 4.91% in men, 9.64% vs 8.17% in female and 8.74% vs 6.68% for both sexes, respectively. Conclusion: We can use FINDRISC to predict the risk of type 2 diabetes mellitus, and screening type 2 undiagnosed diabetes mellitus in Vietnam if the BMI and waist circumference are change criteria for South Asia.
STUDY OF HBEAG, HBV DNA IN PATIENTS WITH HBV- RELATED CIRRHOSIS
Authors: Tran Van Huy , Nguyen Thi Thuan , Ngo Viet Quynh Tram
Published: March 2020

Background: The recent studies concerning antiviral therapy in HBV-related cirrhosis showed the promising results. This study aimed to assess /The aim of this study was to assess the quantity of HBeAg, HBV DNA and identify some related factors in patients with HBV-induced cirrhosis. Patients and methods: 60 patients with HBsAg positive-cirrhosis were enrolled in the study. HBeAg was done by ELISA and HBV DNA was quantified by Realtime PCR assay with kit from Viet A company. Results: The rate of HBeAg positive patients with HBV cirrhosis was: 58.33%; the rate of cirrhosic patients with HBV DNA > 104 copies/ml was 68%. There was a statistically significant relationship between high levels of serum HBV DNA and somes signs of cirrhosis such as grade 3 -ascites, hypoalbuminemia, hyperbilirubinemia, prolonged prothrombin time and thrombocytopenia. Conclusion: The markers of viral replication were still common in patients with HBV cirrhosis, even decompensated cirrhosis.
STUDY ON THE BACTERIA THAT CAUSE HOSPITAL INFECTIONS AT HUE CENTRAL HOSPITAL IN 2012
Authors: Truong Dien Hai , Tran Dinh Binh , Nguyen Thi Nam Lien , et al
Published: March 2020

Objective: To study the bacterial etiologies causing hospital infections at Hue Central Hospital to determine the type of bacteria causing major hospital infections, distribution by local hospital infections, treatment areas contributing to control hospital infections. Subjects and methods: The study described on 311 bacteria strains that isolated in 242 patients who sufer hospital infections with 261 samples from 5/2011 to 5/2012. Results, discussion and conclusions: Hospital infections were 66.9% in male and 33.1%) in female patients, with 261 specimens we isolated 311 bacterial that cause hospital infections. - Respiratory tract infections were the highest rate (37.2%), followed by wound infection (20.2%) and the skin and soft tissue infections (13.2%), bloodstream infections (12,8%). - Five kinds of common infections were: respiratory infections, surgical wound infections, skin and soft tissue infections, urinary tract infections, blood infections. - Sputum is mainly specimens that accounted 35.2%, followed by 34.9% pus specimens, remaining is all kinds of other specimens. - Hospital infections due to Gram-negative bacteria 83.9% that was 5.2 times higher than that of Gram-positive bacterial (16.1%). - The bacterial etiologies causing hospital infections in Hue Central Hospital have five major types: the highest is Acinetobacter baumannii (27.3%), followed by Klebsiella pneumoniae (23.8%), Escherichia coli (15.8%), Staphylococcus aureus (10.6%), Pseudomonas aeruginosa (7.1%). - There are 43 specimens that were isolated two or more types of bacteria (16.5%).
HER2 OVEREXPRESSION IN ENDOSCOPIC BIOPSY SAMPLE OF GASTRIC ADENOCARCINOMA BY IMMUNOHISTOCHEMISTRY
Authors: Le Viet Nho , Tran Van Huy , Dang Cong Thuan , Ta Van To
Published: March 2020

Background and aim: HER2 overexpression by immunohistochemistry is a prognostic maker in gastric cancer and helps to select candidates benefitted from targeted therapy with trastuzumab. This study is aimed at the assessing HER2 overexpression and its relationship with endoscopic and histopathological findings of gastric adenocarcinoma. Objectives and methods: Biopsy samples from 92 gastric cancer patients were examined for HER2 status by immunohistochemical staining. Results: 6.5% of tumors were cardia tumors and 93.5% were non-cardia tumors. Using the Lauren classification, 51.1% were intestinal type and 48.9% were diffuse type. Using WHO classification, 54.3% were tubular adenocarcinoma, 7.6% were mucinous adenocarcinoma, 15.2% were signet-ring cell carcinoma, and 22.8% were undifferentiated carcinoma. 32.6% were well-differentiated, 15.2% were moderately-differentiated, and 52.2% were poorly-differentiated carcinoma. HER2 was positive in 20.7% of gastric carcinomas, 50% cardia tumors and 18.6% non-cardia tumors. HER2 positivity among polypoid, fungating, ulcerated, and infiltrative types were 38.5%, 29.7%, 9.1% and 0%, respectively. HER2 overexpression in intestinal type was higher than that in diffuse type (31.9% vs. 8.9%, p = 0.009). HER2 overexpression in tubular adenocarcinoma, mucinous adenocarcinoma, signet-ring cell carcinoma, and undifferentiated carcinoma was 28.0%, 14.3%, 7.1% and 14.3%, respectively. HER2 overexpressions were different between differentiation degrees: 30% of well-differentiated tumors, 35.7% moderately-differentiated tumors, and 10.4% of poorly-differentiated tumors (p = 0.037). Conclusions: HER2 overexpression was found in 20.7% of endoscopic biopsy sample of gastric adenocarcinoma and was associated with endoscopic gross characteristic, Lauren histologic type and differentiation degree.
EARLY RESULTS OF INGUINAL HERNIA REPAIR BY THE “MESH PLUG” TECHNIQUE
Authors: Nguyen Doan Van Phu , Le Loc , Nguyen Van Lieu
Published: March 2020

Background: In 1989, Lichtenstein I. L., Shulman A. G., Amid P. K., and Montlor M. M. presented an idea of using Mesh Plug to repair the defect inguinal canal. The new technique quickly became accepted by surgeons all over the world for several reasons: faster overall rehabilitation, less postoperative pain, less complication, shorter stay in the hospital and early return to normal activities and work. Materials and method: From Dec 2011 to July 2012, 42 patients with inguinal hernia were surgically treated with 48 Mesh Plugs applied at the Surgery Unit of Hue University of Medicine and Pharmacy. Result: The patients’ average age was 49.12±21.17. There were 25 patients over 40 years old, accounting for 59,5%, and 39 of the group were males, accounting for 92.8%. 10 cases were direct hernia, accounting for 20.8%, and 38 cases were indirect hernia accounting for 79.2%. Based on Nyhus’s classification, there were 33 cases of IIIA and IIIB (68.8%). Based on the position of protrusion, there were 30 cases of right inguinal hernia (62.5%), 18 cases of left inguinal hernia (37.5%), and 6 cases of hernia on both sides. The average size of the deep ring is 2.16±1.64cm. 24 cases used Mesh Plug of medium size (54.5%). The mean operating time was 35.75 minutes. The time of staying in the hospital was 3.52±1.14 days. Quality of life assessment after the surgery showed 46 very good and good cases 95.8% and 2 cases (4.2%) with satisfactory result. No case of bad outcome was recorded. Conclusion: Surgical treatment of inguinal hernia by the Mesh Plug technique is really effective, safe with faster postoperative rehabilitation, less postoperative pain, less complications, shorter hospital stay and early return to normal activities and work.
THE VELOCITY CHARACTERISTICS OF SPERM MOVEMENT BY CASA MACHINE
Authors: Nguyen Anh Thu , Tran Duc Phan
Published: March 2020

Objective: To study the velocity characteristics of sperm movement by CASA machine.
Materials and Method: Using description method, we analyse speed of 136 semen samples in male infertilities.
Results:
(i) In the primary infertile males group: the rate of patients with mobile speed of sperm <30µm/s is 3.64%, > 30-40µm/s is 25.45%, > 40-50µm/s is 50.91% and > 50 µm/s is 20%. These indicators in the secondary infertile males group as follow: 6.17%, 18.52%, 51.85 %, and 23.46%;
(ii) The rate of samples with sperm progressive motility ≥ 25% in primary and secondary infertilities was no statistically significant difference.
Discussion: using the rate of sperm progressive motility, we can’t identify the different between primary and secondary infertility, however speed of sperms were different.
Conclusion: Measuring the speed of sperm provide the characteristics of male infertility.

Key words: Male infertility, sperm, sperm motility, primary infertility, secondary infertility.