bluuebunny/crossref_metadata_2025 huggingface dataset:
The Theological Ontology of Leontius of Byzantium and the Circumscribability Argument in the Iconophile Polemics
Authors:   Novosibirsk State University of Architecture, Design and Arts, Baranov Vladimir
Published: June 2022

The theological contribution of Leontius of Byzantium played a crucial role in adapting the notions of substance and hypostasis from their original Trinitarian to a Christological context. The Leontian concepts, such as enhypostasized substance, distinction between the principle of substance and mode of existence, as well as “relational” ontology of reversed unions and distinctions at the levels of substances and hypostases was adopted by Maximus the Confessor and John of Damascus in their polemical application of Neo-Chalcedonian Christology, as well as the by the Iconophiles of the Second Iconoclasm in support of the circumscribability of Christ.
History and Fantasy on Acholius, the Biographer
Authors:   Universitat de Barcelona, Estrada San Juan Gabriel
Published: June 2022

Among the bogus authors cited in the Historia Augusta, there are some who turn out to be masks for real authors, as part of the picaresque aspect of the work. However, the vast majority are simply disregarded as the product of the biographer’s invention. One of them is Acholius, an author cited on four occasions. We believe that there are reasons to include him in the first group.
Socrates’ humour and Plato’s games in the commentaries of late Neoplatonists
Authors:   Russian Christian Academy for the Humanities, Kurdybaylo Dmitry ,   The Herzen State Pedagogical University of Russia, Kurdybaylo Inga ,   The Bonch-Bruevich Saint-Petersburg State University of Telecommunications
Published: June 2022

The irony of Socrates is one of the essential elements of Plato’s dialogues. However, what appears ironic or playful to modern readers, was not apprehended in the same way by Neoplatonic commentators. For Proclus, one of problematic Plato’s passages concerns the “laborious game,” which refers to the refined eight hypotheses of the Parmenides. Proclus turns to various places of Plato’s dialogues where different games are mentioned. Some of them are mimetic arts, which are partly restricted in Plato’s Republic. Other games are distinguished as pertaining to “old men” and to children: the former is appropriate to philosophers, while the latter is not. Even the “laborious” mode of Parmenides’ playing is given an ontological interpretation. Damascius was aware of the “Parmenides’ game” problem, but he primarily used ready Proclean interpretation. Unsurprisingly, Damascius approaches the conclusion that Parmenides was not playing at all — despite the apparent wording of Plato and minute investigations of Proclus. The extant writings of Simplicius contain no dedicated Platonic commentaries. However, the commentary on Epictetus’ Enchiridion contains a verbose argument on human laughter and its role in a philosopher’s ethos. In general, Simplicius continues Damascius’ trend of rigorous seriousness. Olympiodorus the Younger follows his predecessors in a mere serious reading of Plato, but he acknowledges numerous instances of Socrates’ irony and joking. However, Olympiodorus dissociates Plato from Socrates’ irony and emphasises its purely didactic extent. Generally, we can conclude that the later a Neoplatonic commentator is, the less perceptive to Plato’s humour he appears.
Plato’s Philosophical Mimesis: On the Pedagogical and Protreptic Value of Imperfection
Authors:   Nova Institute of Philosophy, Telo Hélder
Published: June 2022

This article addresses two often perplexing traits in Plato’s philosophical style: first, the fact that Plato’s writings are mimetic, despite the strong criticisms of mimesis we find therein; second, the fact that this mimesis not only features the constitutive defects inherent to any mimesis, but Plato actually increases its imperfection by adding other manifest defects. Based on epistemological and psychological views taken from the Platonic corpus (especially the soul’s tripartition), I show how Plato’s philosophical mimesis uses defectiveness or imperfection to overcome the limitations of mimesis identified in the Republic. To explain this, I argue that Plato’s philosophical mimesis should be primarily conceived as an imitation of people or conversations in which views or arguments are conveyed, but rather as an imitation of the act or practice of philosophical inquiry, and that by rendering this act visible to the reader, the Platonic corpus can better teach how to perform it and better turn readers to a life determined by its performance. This is not without risks because, as a type of mimesis, philosophical mimesis can still lead to misunderstandings or affect the soul in a negative way. However, the quantitative, qualitative and tonal defects Plato introduces in his mimesis of philosophical inquiry cause astonishment and therefore have a provocative effect that helps to reduce those risks and enhance the corpus’ pedagogic and protreptic potential. Consequently, Plato’s philosophical mimesis explores the benefits of mimesis and is in strong contrast with artistic or dramatic mimesis as is understood in Republic X.
Plato on being, time, and recollection
Authors: Pasqualoni Anthony Michael
Published: June 2022

In his dialogues Plato presents two ways of reasoning about Being. First, he constructs contrasting images that depict Being as if it were a spatiotemporal entity. Second, when a higher-order form of reasoning is needed, he uses the concept of the one and its relation to arithmos as an analogue for Being and its relation to not-Being. In Plato’s dialogues, images and arithmos are not mutually exclusive. Rather, they are complementary; Plato sometimes employs an image of a whole to portray that which is neither spatial nor temporal. Such an image is determined by a conceptual structure that joins many into one. Focusing on the Sophist and the Meno, I argue that the theory of recollection presents such an image.
Aristotle and Ptolemy I Soter
Authors:   Institute of Philosophy and Law SB RAS, Brovkin Vladimir
Published: June 2022

The article discusses the influence of Aristotle on Ptolemy I. It is established that Ptolemy I managed to put into practice the ideas of Aristotle about a virtuous monarch and a state in which citizens lead a contemplative life. The reign of Ptolemy I fully corresponded to Aristotle's ideas of absolute monarchy. According to Aristotle, a monarch can have absolute power only if he has exceptional virtue. According to Aristotle, the main political virtue is prudence. This virtue is associated with making the right decisions in public administration. As we have shown, Ptolemy I was a very prudent monarch who managed to build a strong and prosperous state in Egypt. Also, Ptolemy I brought to life the idea of Aristotle on the establishment of a major research center. The Museum and Library in Alexandria became the place where Greek scientists and philosophers could lead a contemplative life in full accordance with Aristotle's views on the ideal state.
Objective, Transcendental, Formal Truth: The Question on Truth in the Early Modern Jesuit Metaphysics and Scholastic Theology
Authors:   Saint Petersburg State University of Aerospace Instrumentation, Ivanov Vitaly
Published: June 2022

The article studies the transformation of the traditional Peripatetic concept of truth in the Jesuit metaphysics and scholastic theology of the Early Modern period. The essence of this transformation is described as an increasing tendency towards a convergence of the classical scholastic concept of the "transcendental truth of things" and the new concept of "objective truth” and to replace the first concept with the second. First, the article describes and analyzes the classic for the later Jesuit tradition disposition of the concept of truth in a metaphysical treatise on truth within the framework of the VIIIth Metaphysical Disputation by Fr. Suárez and shows the traditional opposition of the formal truth of knowledge or judgment and transcendental truth as an attribute of being as such. Secondly, the article shows that an essential characteristic of Suárez's metaphysical concept of truth is the reality of truth, and not objectivity as conceivability, not limited to real entity. It is indicated that Suárez is quite familiar with the concept of “objective truth”, but applies it only in his theology, while excluding it from metaphysics. Thirdly, the article looks into the theological motives for the formation of the concept of objective truth as key for the Jesuit theology of ‘scientia media’. Finally, the article analyzes the content of the treatise on the "objective truth" of things in the Pharus scientiarum by S. Izquierdo, and also demonstrates the motives and consequences of the identification of objective and transcendental truth in Izquierdo’s ontology.
Unfinished work of Thucydides
Authors:   Saint Petersburg State University, Panchenko Dmitri ,   Higher School of Economics (Saint Petersburg branch)
Published: June 2022

Thucydides' statement that he described the entire war up to the surrender of Athens (V, 26, 1) must be taken in strict accordance with his words. On the whole, his work was completed; all that remained was to fix, supplement, decorate. The fact that in the published version the text breaks off at the presentation of the events of 411 is due to the following circumstances. During his stay in Athens, where he returned in the early summer of 404 after almost twenty years of exile, Thucydides introduced individual parts of his work to those who wish. There was a rumor about the work of Thucydides. The attention of Lysander's friends and henchmen was attracted by the presence in the work of detailed information about the establishment in Greek cities of political clientele, who were much more dependent on Lysander than on the Spartan state. The kings and other persons in the Spartan government, pushed into the background by Lysander, saw these actions of Lysander as the basis for the gradually carried out coup d'état by him. Authoritative information about the clientele founded by Lysander could pose a great danger to his career. Meanwhile, Thucydides, for some reason, returned to his Thracian possessions. Lysander went there too. In the fall of 404, Thucydides was murdered, and the manuscript of his work was stolen. Everything that seriously compromised Lysander was removed from it; the rest was saved and taken to Sparta. In the spring of 395, Lysander died in a battle. In the fall of 394, Agesilaus, who had returned to Sparta from Asia, searched the house of Lysander in order to find materials revealing that he was preparing a coup d'état. Along with the planted fake, books of the history of Thucydides were also discovered. After making sure that they did not contain anything fundamentally harmful to Spartan politics, Agesilaus handed the manuscript to Xenophon, an officer of his army, an Athenian exile and a credible writer. Xenophon published the intact part of the manuscript as it was, without editing it. The materials of the damaged part formed the basis of the first two books of his Hellenica.
Testing Burrows' Delta on Ancient Greek Authors
Authors:   Higher School of Economics, Alieva Olga V.
Published: June 2022

This paper tests the effectiveness of Burrow’s Delta Method on a corpus of selected prose writings in ancient Greek. When tested on a corpus of fourteen and eight authors, the method yields good results with relatively small samples (1000, 3000, and 5000 words) and different word frequency vectors (100, 200, 500 words), but its performance is worse with texts of similar genres (oratory, historical or medical writings). We conclude that it is the generic proximity that influences the results of classification most. However, in cases where confusion is more likely, such as the writings of Demosthenes and Aeschines, the method proves effective for shortlisting potential authors. Shortlists can give an adequate idea of a sample’s nearest neighbors while leaving some freedom for the researcher in interpreting the results.
Classical Studies as Cultural Philosophy: Tadeusz Zielinski and Karl Kerényi
Authors:   Institute of Philosophy RAS, Petroff Valery V.
Published: June 2022

The article discusses the concept of three “Renaissances”, as outlined by Tadeusz Zielinski in the essay “The Ancient World in the Poetry of Apollon Maykov" (1899). By “Renaissances” Zielinski meant the periodic appeals of a particular European culture to the ancient legacy and, at the same time, the beneficial cultural consequences of such appeals. According to Zielinski, two renaissances of antiquity have already taken place: the “Italian” and the “Germanic” (in the 18th–19th centuries); the next should be the “Slavonic” Renaissance. The object of attention is the imagery of Zielinski, who compares the influence of antiquity on new cultures with an oceanic flow that carries the heat of the south to the cold shores of northern Europe. It is shown that Zielinski is influenced by his immediate sources — the cultural and philosophical constructions of Hippolyte Taine and Friedrich Paulsen. It is argued that Paulsen’s text depends on Taine’s, and Zielinski uses them both. The corresponding views of Russian philologists and philosophers, who shared Zielinski’s concept, are considered. On the example of the “Hungarian” works of Karl Kerényi of the 1930s, it is shown that the belief in the beneficence and the need for the revival of antiquity for national culture was not an exclusively Russian phenomenon, but was a basic ideological archetype of the international community of European classical philologists and scholars of the first half of the 20th century.
Estudos Críticos do Discurso
Authors: Carrazzoni Veronica del Pilar Proaño
Published: June 2022

Neste artigo, discutimos sobre as categorias sociais, poder e dominação, dentro do quadro da Análise Crítica do Discurso (ACD) (FAIRCLOUGH, 2001; PEDROSA, 2005, MEURER, 2005; RESENDE; RAMALHO, 2014), bem como poder e abuso de poder, no marco sociocognitivo dos Estudos Críticos do Discurso (ECD) (CÁRDENAS, 2018; VAN DIJK, 2008, 2012, 2015, 2016). Na segunda perspectiva, abordamos ainda as cognições sociais, conhecimento e ideologia. Tais elementos foram profícuos na construção da metodologia de análise do discurso jornalístico, na nossa tese de doutorado “Poder e desigualdade: a representação dos pescadores e pescadoras artesanais nas notícias do Jornal do Commercio” (FOX, 2021). Com base neles, refletimos aqui sobre o papel que o discurso dos meios de comunicação de massa e dos próprios jornalistas tem na (re)produção de formas abusivas de poder. Em uma instância maior, buscamos contribuir com pesquisadores de filosofia e outras ciências, que estão iniciando sua trajetória no campo dos estudos do discurso.
Discurso e Ontologia Política
Authors: Almeida Leonardo Monteiro Crespo de
Published: June 2022

O objetivo desse artigo reside em esclarecer certos pressupostos da teoria política de Ernesto Laclau a partir do conceito de discurso. Através desse conceito, o artigo pretende esclarecer qual seria a relação entre a teoria do discurso e uma ontologia política, e de que maneira a proposta laclauliana reside em uma reformulação de algumas premissas do marxismo através de uma cuidadosa assimilação de determinadas posições associadas a autores pós-estruturalistas, como Derrida e Foucault. O desenvolvimento dessa relação, por fim, vai permitir mostrar como Laclau relaciona os âmbitos do social e do político na formulação de sua proposta teórica.
Narrativas visuales en el paisaje semiótico urbano para construir memoria colectiva
Authors: Pardo Abril Neyla Graciela
Published: June 2022

El siglo XXI se ha caracterizado por vincular grandes grupos sociales con formas de comunicación en las que todos los recursos semióticos disponibles en la sociedad son usados por los interlocutores en el proceso de construir significado. Desde las reflexiones de Kress (2010); Ledin y Machin (2018) y Van Leeuwen y Djonov (2015), entre otros, la investigación de los discursos multimodales y multimediales, en perspectiva crítica, sigue siendo una cuestión relevante para explicar cómo ocurren los eventos comunicativos contemporáneos y determinar sus implicaciones para la construcción de sociedades más justas e incluyentes. La conceptualización del discurso integra en el abordaje los procesos de diseño, producción, interpretación y circulación social, a través de los diferentes modos – sistemas sígnicos-, las maneras como se interrelacionan sus distintos niveles estructurales y funcionales en tanto acción social, y las formas como se socializan conocimientos en los muros de la ciudad, como recurso tecnológico. Se propone hacer una reflexión sobre el enfoque aplicado a los Estudios Críticos del Discurso Multimodal y Multimedial (ECDMM) para verificar la ineludible tarea de asumir su análisis e interpretación, desde un marco epistémico transdisciplinario, lo cual implica un proyecto más amplio que involucra la memoria y la construcción de paz. Se asume el discurso como parte del paisaje semiótico urbano de Bogotá, en el que se destaca la integración de sistemas sígnicos de orden visual-verbal como la lengua, y visual-gráfica como la imagen y el color. La pared en la Ruta de la Memoria se entiende como el soporte tecnológico a través del cual se distribuyen formas de conocer la realidad, en este caso, sobre la memoria. Los muros se convierten en recurso mediático urbano, al soportar la materialización de los contenidos multimodales, adquiriendo carácter multimedial. El discurso público que circula por la “ruta de la Memoria” crea para el ciudadano una atmósfera que contribuye a estructurar interacciones comunicativas, que podrían asimilarse a los discursos de las redes sociales, o a otras formas de comunicación mediática contemporánea. Se entiende la importancia de la producción de los significados que surgen en la integración de los sistemas semióticos articulados al orden visual, para reconocer la relevancia del discurso multimodal y multimedial que apropia la ciudad en una coyuntura sociopolítica, articulada al cumplimiento del Acuerdo de Paz (2016). Se propone una posición metodológica transdisciplinaria, que permita abordar los murales de manera crítica, desentrañando las representaciones que se encarnan en los discursos que circulan públicamente y, hacen de la interacción comunicativa un fenómeno omnipresente en la vida socio cultural.
concepção de atividade filosófica em Herbert Marcuse
Authors: Menezes Anderson de Alencar , Silva José Bezerra da
Published: June 2022

Com este artigo buscamos identificar os traços essenciais da atividade filosófica segundo a concepção de Herbert Marcuse, distribuídos na análise dos conceitos de filosofia, filósofo, sujeito revolucionário, como também o significado de socialismo democrático, ponto mais alto de libertação dos seres humanos, que pode vir a ser alcançado mediante a ação dos movimentos sociais. Seguimos o método crítico-dialético para a realização deste trabalho, por nos fornecer os meios adequados de compreensão e articulação da totalidade, particularidade e singularidade da sociedade contemporânea e suas tendências historicamente construídas pela lógica do capital. Definimos como objetivos os seguintes pontos: investigar o conceito de atividade filosófica na concepção de Marcuse e também descrever os conceitos de filosofia, filósofo e de sujeito revolucionário, articulando esses aspectos com o seu ideário de libertação humana, formatado no socialismo democrático, para cuja realização recorre a diversos movimentos sociais. No conjunto, o artigo busca responder/ solucionar o seguinte problema: de que maneira a atividade filosófica contribuirá para a construção de uma sociedade livre e democrática?  A fim de encontrar uma resposta/solução plausível para o problema suscitado, faz-se necessário percorrer diversas obras do filósofo Marcuse e também obras e artigos de alguns dos seus abalizados estudiosos e estudiosas somados a obras de outros autores engajados com uma leitura de mundo suficientemente capaz de transformá-lo para que os seres humanos vivam, de fato, humanizados.
Molecular Partition Coefficient from Machine Learning with Polarization and Entropy Embedded Atom- Centered Symmetry Functions
Authors: Zhu Qiang , Jia Qingqing , Liu Ziteng , Ge Yang , Gu Xu , Cui Ziyi , Fan Mengting , Ma Jing
Published: June 2022

Efficient prediction of the partition coefficient ($\log P$) between polar and non-polar phases could shorten the cycle of drug and materials design. In this work, a descriptor, named $\langle q-ACSFs \rangle_{conf}$, is proposed to take the explicit polarization effects in polar phase and conformation ensemble of energetic and entropic significance in non-polar into considerations. The polarization effects are involved by embedding the partial charge directly derived from force fields or quantum chemistry calculations into the atom-centered symmetry functions (ACSFs), together with the entropy effects which are averaged according to Boltzmann distribution of different conformations taken from similarity matrix. The model was trained with the high-dimensional neural networks (HDNNs) on a public dataset PhysProp (with $41039$ samples). Satisfactory $\log P$ prediction performance was achieved on three other datasets, namely, Martel ($707$ molecules), Star \& Non-Star ($266$) and Huuskonen ($1870$). The present $\langle q-ACSFs \rangle_{conf}$ model was also applicable to the $n$-carboxylic acid with the number of carbon ranging from $2$ to $14$ and the $54$ kinds of organic solvents. It is easy to apply the present method to arbitrary sized systems and give a transferable atom-based partition coefficient.
What data are most valuable to screen ionic liquid entrainers for hydrofluorocarbon refrigerant reuse and recycling?
Authors: Garciadiego Alejandro , Befort Bridgette , Franco Gabriela , Mazumder Mozammel , Dowling Alexander
Published: June 2022

Separating azeotropic mixtures of hydrofluorocarbons (HFCs) for reuse and recycle is environmentally and economically imperative. While ionic liquid (IL)-enabled HFC separations show promise, Edisonian trial-and-error screening for the optimal IL entrainer is intractable and expensive. Here we propose an open-source, equation-oriented modeling framework to rapidly translate HFC/IL solubility data into regressed thermodynamic models which can be used for process design under uncertainty and rapid IL screening. Moreover, we use data science and process systems engineering tools to contemplate which data are the most valuable for IL screening. We find that binary solubility data collected at multiple temperatures is adequate for separation process design and newly available ternary solubility measurements should be reserved for validation. Additionally, we use uncertainty quantification analyses to show up to 10% experimental error is acceptable for IL screening decisions. Informed by these results, we recommend a multi-step workflow for IL screening.
A Modified Electrostatic Complementary Score Function and Its Application Boundary Exploration in Drug Design
Authors: Zhao Liming , Wang Huting , zhang yingsheng
Published: June 2022

In recent years, machine learning (ML) models have been found to quickly predict various molecular properties with accuracy comparable to high level quantum chemistry methods. One such example is the calculation of electrostatic potential (ESP). Different ESP prediction ML models were proposed to generate surface molecular charge distribution. Electrostatic complementarity (EC) can quantitatively apply ESP data to scale the complementarity between a ligand and its binding pocket, leading to the potential to increase efficiency of drug design. However, there is not much research discussing EC score functions and its application boundary. We propose a new EC score function modified from the one originally developed by Bauer and Mackey, and confirmed its effectiveness against the available Pearson’s R correlation coefficient. Additionally, the application boundary of the EC score and two indices used to define the EC score application scope will be discussed.
MetalWalls: Simulating electrochemical interfaces between polarizable electrolytes and metallic electrodes
Authors: Coretti Alessandro , Bacon Camille , Berthin Roxanne , Serva Alessandra , Scalfi Laura , Chubak Iurii , Goloviznina Kateryna , Haefele Matthieu , Marin-Laflèche Abel , Rotenberg Benjamin , Bonella Sara , Salanne Mathieu
Published: June 2022

Electrochemistry is central to many applications, ranging from biology to energy science. Studies now involve a wide range of techniques, both experimental and theoretical. Modelling and simulations methods, such as density functional theory or molecular dynamics, provide key information on the structural and dynamic properties of the systems. Of particular importance are polarization effects the electrode/electrolyte interface, which are difficult to simulate accurately. Here we show how these electrostatic interactions are taken into account in the framework of the Ewald summation method. We discuss, in particular, the formal set up for calculations that enforce periodic boundary conditions in two directions, a geometry that more closely reflects the characteristics of typical electrolyte/electrode systems and presents some differences with respect to the more common case of periodic boundary conditions in three dimensions. These formal developments are implemented and tested in MetalWalls, a molecular dynamics software which captures the polarization of the electrolyte and allows the simulation of electrodes maintained at a constant potential. We also discuss the technical aspects involved in the calculation of two sets of coupled degrees of freedom, namely the induced dipoles and the electrode charges. We validate the implementation, first on simple systems, then on the well-known interface between graphite electrodes and a room-temperature ionic liquid. We finally illustrate the capabilities of MetalWalls by studying the adsorption of a complex functionalized electrolyte on a graphite electrode.
Low humidity dependence of proton conductivity in modified zirconium (IV)-hydroxy ethylidene diphosphonates
Authors: Ogawa Takaya , Anilkumar Gopinathan M. , Tamaki Takanori , Ohashi Hidenori , Yamaguchi Takeo
Published: June 2022

Proton conducting materials play an essential role in various fields of science and many applications, such as polymer electrolyte fuel cells (PEFCs). However, their proton conductivities suffer from the strong dependence on relative humidity (RH) and severely decrease at low RH conditions. Here, we synthesized zirconium (IV)-hydroxy ethylidene diphosphonates (ZrHEDP), which have phosphonic acid groups at a close distance. As the acidic groups are more concentrated in ZrHEDP, the proton conductivity exhibits lower dependence on the RH. In particular, the ZrHEDP with the largest amount of phosphonic acid groups among the examined samples showed the lowest RH dependence; the proton conductivity at 40% RH remained 2/3 of the conductivity at 95% RH, whereas a representative electrolyte, Nafion, at 40 % RH showed 1/5-1/20 of its conductivity at 95% RH.
LA FORMACIÓN ECONÓMICA DE LA SOCIEDAD ARGENTINA II. De la acumulación originaria al desarrollo de su especificidad hasta 1930
Authors: Iñigo Carrera Juan
Published: June 2022

Para que el proceso de conocimiento se enfrente a su objeto en la integridad de su determinación concreta es necesario partir de la forma más simple del objeto en cuestión, y reproducir a éste con el pensamiento al acompañarlo virtualmente en el despliegue de sus determinaciones, por mucho que éstas parezcan ser lo contrario de aquel contenido más simple suyo. Tal es el curso que sigue la presente investigación a fin de contestarse acerca de la forma nacional específica con que la sociedad argentina actúa como sujeto en el proceso de desarrollo de las fuerzas productivas del trabajo. Esta investigación no consiste en el despliegue histórico del curso seguido por la sociedad argentina a lo largo del período considerado, como un proceso cuya unidad se encuentra dada simplemente por tratarse de un mismo ámbito nacional. Por el contrario, su curso tiene por eje la puesta en evidencia de los rasgos que presenta dicho desarrollo histórico como expresiones de la existencia de una determinación específica propia de la forma que toma el proceso nacional argentino de acumulación de capital.
Endotypes and Immune Cells in Severe Asthma
Authors: Rijavec Matija , Korošec Peter
Published: June 2022

Severe asthma accounts for a small proportion of asthma prevalence, however due to high requirements for treatment the majority of medical resources are directed toward those patients. Asthma is a highly heterogeneous disease, an umbrella diagnosis for several diseases with variable clinical presentations (phenotypes) and distinct mechanistic pathways (endotypes), and its pathophysiology is not yet completely understood. Thus despite similar clinical symptoms, asthma patients may respond very differently to the same therapeutic interventions. Asthma endotypes are currently regarded as type 2 high (T2-high) or non-T2. Th2 cells, innate lymphoid cells, eosinophils and mast cells are the most important cell types associated with T2- high asthma, on the other hand neutrophils, Th1 and Th17 cells are involved in non-T2 asthma. As more and more innate and adaptive immune cell types and mediators are identified as important drivers of asthma, asthma endotype definitions are still fluid and continue to evolve. The identification and understanding of the molecular mechanisms of different asthma endotypes, that reflect a highly variable response to different treatments, will lead to more precise asthma management and better outcomes in patients.
Lung Function Tests to be Used in Severe Asthma: Spirometry and Bronchodilator Test, Diffusion Capacity for CO, Induced Sputum, Body Plethysmography, Electronic PEF Measurements
Authors: Fležar Matjaž
Published: June 2022

Lung function tests are the cornerstone for asthma diagnostic procedure and patient follow-up and is complementary to other phenotyping tools used later for precision diagnosis. Spirometry and bronchodilator tests are used to define degree and reversibility of airway disease, diffusion capacity of the lung for CO is used as exclusion tool for comorbid diseases (particularly COPD), Body plethysmograph is used in small airway asthma to determine the degree of air trapping and hyperinflation, electronic PEF monitoring is used for work-related asthma characterization and targeted sputum examinations (induced sputum protocol) are used in immune phenotyping process. In hands of pulmonologist these tests (not all of them routinely used) are necessary to separate uncontrolled asthma from severe asthma phenotype.
Türk-İran Dış Politika Açılımlarının Arap Basınında Algısı: Arap Baharı (2011-2015)
Authors: DOGAN Battal
Published: June 2022

“Bahar” olgusuyla kavramsallaştırılan Arap halk-rejim çatışmaları, özgürlükler ve ekonomik refah adına değişim isteğiyle başladı. Arap Baharı en yıkıcı etkisini devrimci-cumhuriyetçi ülkelerde göstermiştir. Tunus ve Mısır’da kısa süren Bahar, iç dinamiklerin gücü oranında şekillenmiştir. Libya ve Suriye’de Bahar süreci uzadıkça bölgesel ve küresel güçleri içine çekmiştir. Halk-rejim çatışmalarının güvenlik ve insani boyutu Türkiye’yi sürecin içine çekerken, İran’ın mezhepsel yayılmacılığına da yeni bir kapı açmıştır. Bu bağlamda, farklı nedenlerle Bahar sürecine müdahil olan Türkiye ile İran’ın bu dış politika açılımları Arap basınına nasıl yansıdı, sorusunu akla getirmiştir. Makalede Arap basını örneklemlerinden çıkarılan verilere içerik analizi (İA) ve söylem analizi (SA) uygulanarak karma bir yöntem kullanılmıştır. Analiz birimi olarak da gazetelerin haber çerçevelemeleri yerine, köşe yazıları tercih edilmiştir. Arap Baharı’na yönelik Türk-İran dış politika açılımlarının ağırlıklı olarak milliyetçi ve İslamcı yazarlar tarafından köşe yazılarına taşındığı tespit edilmiştir. Milliyetçi söylemi ‘ne Türk Sultanı ne İran Mollası’ şeklinde özetlemek mümkündür. İslamcı yazarların bu konuda ses tonları çok daha düşüktür. Türk siyasal İslam modelini şartlı olarak kabul eden İslamcılar, İran’ın mezhep eksenli modeli ve yayılmacılığının Sünni bir ittifakla durdurulmasını önermektedir.
Strategi Pemasaran Serbuk Jamu Instan UMKM Tiga Dara di Masa Pandemi Covid 19
Authors: Purwantisari Susiana , Ardiansari Anindya , Jannah Siti Nur , Saputro Rizky Wahyu
Published: June 2022

Empowerment of Micro, Small and Medium Enterprises (MSME), requires model empowerment, which includes increasing existing MSME to be more advanced in order to be able to compete tightly in free market competition. Since ancient times, empon empon has been proven to have medicinal properties as herbal medicine, which is not only used as a medicine but also as a beauty treatment. One of the MSME that processes empon-empon into instant herbal medicine is Tiga Dara MSME which is located at Jalan Urip Sumoharjo No. 45 East Ungaran Subdistrict, Semarang Regency. Instant herbal powders produced by UD Tiga Dara include instant powders of Ginger, Turmeric, Temulawak, Mahkota Dewa, Kencur etc. The importance of maintaining body immunity during the COVID-19 pandemic is closely related to the availability of instant herbal powder products with empon-empon raw materials, especially ginger. During this pandemic, the demand for instant herbal medicine powder has increased, but Tiga Dara MSME still have limitations in the sales system. The method used in this community service is in the form of training and mentoring MSME in making web and social media as a means of marketing instant herbal powder products. This service aims to assist MSME in marketing their products in order to improve the economy of Tiga Dara MSME. With the existence of the Web and social media as one of the media for product marketing, it is hoped that it can increase sales from MSME and can improve the community's economy so that it can achieve community welfare.
Pemberdayaan Masyarakat Desa Sendangarum DIY dalam Mempersiapkan Pembentukan Badan Usaha Milik Desa (BUMDes)
Authors: Sakir Sakir , Walinegoro Bhakti Gusti , Wahyuni Herpita
Published: June 2022

The Real Work Lecture Program (KKN) of the University of Muhammadiyah Yogyakarta provides support for the establishment of Village Owned Enterprises (BUMDes). The benefits of BUMDes are to improve the village and community economy, increase original village income, and improve potential village management according to community needs and economic equity. The implementation of the Community Service Program was held in Sendangarum Village, Sleman, Yogyakarta Special Region, from October 15 to December 15, 2021, in the context of community service, which aims to optimize the potential and progress of the village by preparing villages to form BUMDes. The method of implementing the program is by socializing the importance of establishing BUMDes, making complete information about villages through making village profiles that are useful as village introductions, and exploring village potential. The appearance of an attractive Instagram logo and social media is a strategy to increase product sales packaged in preparing for the formation of BUMDes. Assistance and training with training on institutional aspects of BUMDes, BUMDes Innovation Training, BUMDes Digitization Training, and BUMDes Sustainability Training help prepare for the formation of (BUMDes). Mentoring and training facilitated by the University of Muhammadiyah Yogyakarta support realizing the ideals of Sendangarum Village to have a BUMDes.
Penerapan Sustainable Living pada Rumah Tangga dengan Pembuatan Produk Kesehatan Ramah Lingkungan
Authors: Sukamdi Dyani Primasari , Octavia Mega , Kurniawan Muhammad Fariez , Dewi Pramitha Esha Nirmala , Rahayu Inayati Murwani
Published: June 2022

Public outrage over the Covid-19 pandemic has a detrimental effect on the habit of staying at home and contributes to increased household waste. The temporary closure of the TPTS Piyungan Yogyakarta has exacerbated the problem of garbage and household waste accumulation. Al Fatah Kindergarten, in collaboration with the School of Pharmacy Universitas Muhammadiyah Yogyakarta, wishes to encourage the community to practice environmental stewardship. The environmental conservation effort will begin at home with domestic waste management. This guidance tries to broaden the public's perception and understanding of waste. Online counseling and training are available on two primary topics: "Wise Waste Management Begining at Home" and "Making Soap and Candles from Waste Cooking Oil." "Wise to Manage Waste Beginning at Home" discusses how to separate waste and repurpose it starting with household waste. Meanwhile, "Making Soap and Candles from Used Cooking Oil" provides instruction on how to make simple soap and candles from used cooking oil, a common household waste. According to the questionnaires distributed to participants, some participants gained additional insight into how to incorporate sustainable living practices, particularly waste management, into their daily lives. Additionally, participants can comprehend the definition and practice of  garbage charity. As many as 94 percent of service users expressed satisfaction with their waste processing experience.
Eksistensi Mahasiswa dalam Peningkatan Akademik Melalui Program Kampus Mengajar di SDN 04 Purwosari Kecamatan Comal Kabupaten Pemalang
Authors: Cahyaning Tias Nova Indriyani , Indriyani Septi , Rahmawati Diana , Yasin Bahtiar , Rizal Fahrur , Damayanti Anita , Suranto Suranto
Published: June 2022

The COVID-19 pandemic that is currently happening in Indonesia has had a major impact in all fields, one of which is education. In this pandemic period, education in Indonesia must be carried out online, which results in the inhibition of direct interaction between teachers and students. Therefore, the Ministry of Education and Culture organizes a Teaching Campus program, which is part of the Independent Learning Campus (MBKM) policy. This Teaching Campus Program aims to provide solutions for elementary schools affected by the pandemic by empowering students who live around the school area to assist teachers in carrying out learning activities in the midst of the COVID-19 pandemic. The results of the study show that the implementation of the Class 2 Teaching Campus at Public Elementatry School 04 of Purwosari includes the following: First, teaching is carried out by home visits, through online media, and face-to-face (after limited PTM verification). Second, technology adaptation by helping teachers prepare materials sent via WhatsApp media, and third, assisting administration in the form of allocating textbooks in libraries and collecting student data.
Pelatihan Blended Learning Hypercontent with Hyperlink Menggunakan QR Code untuk Guru Sekolah Menengah Pertama sebagai Strategi Pembelajaran Matematika di Purwakarta
Authors: Turmudi Turmudi , Hidayat Asep Syarif , Widayanti Widayanti , Diana Nana , Yuliyanto Aan , Nurhasanah Riska , Jalaludin Ahmad Rizal
Published: June 2022

As we all know that the Covid-19 pandemic has paralyzed various aspects including education. In the field of education, learning habits are limited face-to-face and are required to apply strict health protocols. On the other hand, the ability of teachers to teach their field of study using online methods still has limitations, for example, the ability to design teaching materials and transfer learning using media is considered to be very limited. Training and improving teacher competence through blended learning and the use of hyper content with hyperlinks are seen as one of the solutions so that teachers can design teaching materials oriented to text and image processing by using QR Codes. The subject matter, whether text, images, graphics, diagrams, or models designed by the teacher, can be delivered by using hyper content and inserting links to being content on the internet such as YouTube, to enhance the knowledge supply of teachers and students. The training activities were carried out face-to-face at the New Building, UPI Campus in Purwakarta, involving 20 Junior High School Teachers and 18 Madrasah Tsanawiyah Teachers in Purwakarta Regency. The results of the activity show that the blended learning hyper content with hyperlink training can improve the ability of teachers in designing engaging, interactive digital modules or teaching materials that are rich in content that can be accessed online anytime and anywhere or printed and then scanned via QR Code when students want to access the provided learning content. Thus, blended learning hyper content with hyperlinks can be used as an effective solution in improving the ability of teachers to design teaching materials during the COVID-19 pandemic and the implementation of limited face-to-face learning.
PEMODELAN PERSEPSI PEMBELAJARAN ONLINE MENGGUNAKAN LATENT DIRICHLET ALLOCATION
Authors: Fernanda Jerhi Wahyu
Published: June 2022

Latent Dirichlet Allocation (LDA) merupakan metode untuk pemodelan topik adalah yang didasarkan kepada konsep probabilitas untuk mencari kemiripan suatu dokumen dan mengelompokkan dokumen-dokumen menjadi beberapa topik atau kelompok.   Metode ini masuk dalam unsupervised learning karena tidak ada label atau target pada data yang dianalisis. Penelitian ini bertujuan untuk mengelompokkan persepsi tentang pembelajaran online ke dalam beberapa topik menggunakan metode LDA. Data penelitian ini adalah data primer yang dikumpulkan melalui formulir online. Hasil analisis menunjukkan bahwa pemodelan LDA menggunakan 6 topik memiliki coherence score paling besar. Hasil visualisasi data text menggunakan wordcloud didapatkan kata tidak memiliki frekuensi kemunculan terbesar. Penentuan jumlah topik yang optimal berdasarkan coherence score, didapatkan pemodelan LDA dengan 6 topik adalah yang paling optimal. secara garis besar terdapat beberapa kata yang saling beririsan dengan topik yang lain. Hasil pemodelan memberikan gambaran bahwa persepsi/pandangan mahasiswa terdapat pembelajaran online terkait pemahaman materi yang diberikan dosen, sinyal atau jaringan internet, kuota, dan tugas. Pada kata-kata terkait pemahaman materi, mahasiswa memberikan pandangan bahwa mereka tidak dapat memahami dengan baik materi yang diberikan oleh dosen.
OPTIMASI SETTING PARAMATER CLEANLINESS, KETEBALAN, DAN JENIS CAT PADA MATERIAL BAJA A572 TERHADAP DAYA REKAT CAT
Authors: Rachman Farizi , Karuniawan Bayu Wiro , Firdiandani Anggie Madhu
Published: June 2022

The manufacturing process consists of several stages, one of them is the finishing stage. The finishing stage at PT. Supra Surya Indonesia consists of surface preparation process and painting process. The adhesion of the paint must meet the criteria to get good protective quality for the product. In the painting process, there are always defective products that must go through the repair stage before packing. Process parameters such as cleanliness level of the material surface and paint thickness need to be considered and the selection of the type of paint will affect the results of painting. Based on the problems above, it is necessary to research the analysis of process parameters that can optimize the value of paint adhesion. This study uses the Taguchi method so that the contribution of cleanliness parameters is 49.6995 %, paint thickness is 5.0014 %, and paint type is 40.4139 %. The optimum combination of parameters is cleanliness Sa 2 1/2, the thickness of 100 µm, and the type of phenolic epoxy paint.
VALUES AND COPARENTING: A CROSS-SECTIONAL STUDY WITH ITALIAN FAMILIES
Authors: PISAURO Marianna , BARNI Daniela , TRAVAGLINI Emanuele , DE STASIO Simona , RAGNI Benedetta
Published: June 2022

Objectives. The main purposes of this study were to: examine possible existing relationships between couple values and coparenting quality reported by both partners of cohabitants heterosexual couples; investigate whether couple values explain coparenting quality reported by both partners of cohabitants heterosexual couples. Material and methods. 94 Italian heterosexual couples with at least one child under the age of 13 years were enrolled. Both mothers (Mage = 41.25, SD = 6.82) and fathers (Mage = 44.21, SD = 6.97) were asked to fill in two self-report questionnaires: The Portrait Values ​​Questionnaire [PVQ] for couple values and The Coparenting Relationship Scale for the coparenting quality. Results. The main findings of regression model analysis conducted showed that Self-Transcendence resulted the most important predictor (β = .412, t = 4.253, p = .000) for coparenting quality perceived by fathers. In contrast, Conservation resulted the most important predictor (β = .239, t = 2.086, p = .040) for coparenting quality perceived by mothers. Conclusions. From the results obtained, the authors found an important preference for parents of respecting one’s cultural traditions, respecting the rules, being tolerant, ensuring the well-being of others by mitigating impulsive behaviors that could harm others physically and emotionally. The presence of these values ​​could allow both partners to implement supportive and collaborative behaviors, agree on education-related issues for their children, and feel close and allied in upbringing their child. Keywords: co-parenting, couple values, mutual support, couple’s well-being.
THE SEXUAL ABUSER, CHARACTERISTICS AND RISK FACTORS – LITERATURE REVIEW
Authors: DINA Maria - Miana , GOMEZ Jose Manuel Rodriguez , RADA Cornelia
Published: June 2022

Objective. The objective of this study was to examine some dimensions of personality encountered among people with difficulties in controlling sexual impulses, depending on the gender of the aggressor, as well as to highlight the main predictors regarding the probability of committing sexual abuse. Material and methods. 48 studies were analyzed, of which 13 qualitative and 35 quantitative. The qualitative researches were mainly based on observation or semi-structured interview, and the quantitative ones were based on descriptive statistics, correlational tests. The size of the samples ranged from 51 to 2950 participants. The search covered the period from 1997 to 2020. Results. Men and women who have committed sexual offences have both common characteristics such as mental disorders, inadequate sexual style, lack of remorseful or empathetic feelings towards the victim, tendency towards criminal behavior, and differences. These were represented by the way they approach the victim, while men tend more towards the use of manipulation, women choose dissimulation. The risk factors in the occurrence of this crime were: the close relationship between the aggressor and the victim, the age specific to the aggressor’s youth stage, spatio-temporal factors correlated with the time of year and the time of day, the existence of a preferential pattern and dysfunctions of the social environment. Conclusions. A customized intervention is required, depending on the specificity of the clinical frame, on the type of socioeconomic and educational environment of origin and on the experiential history of each person in this criminal category. In the case of men, the approach must keep in mind the relational-value side, and in the case of women the affective sphere, taking into account the involvement of a wide range of emotions. Keywords: sexual assault, pedophilia, personality, rape, risk.