bluuebunny/crossref_metadata_2025 huggingface dataset:
Sistemas silvopastoriles para la producción ganadera en el Centro de Producción Limón Rocío de la UNSM-T
Authors: Roque Alcarraz Roberto Edgardo , Silva Del Águila Justo German , Barrera Lozano Marvin
Published: July 2022

El adecuado desarrollo ganadero debe haber un punto de equilibrio entre la producción animal y los servicios ambientales. El objetivo del estudio fue realizar evaluaciones agronómicas en cuatro sistemas silvopastoriles (SSP). Para ello, se instalaron 16 ha de pasturas (sistema de pastura sola con Brachiaria brizanta; sistema de manejo con sucesión vegetal; sistema de pastura con leguminosas arbustivas; y sistemas como bancos de energía y proteínas) en un ecosistema de bosque seco tropical en la región San Martín, Perú, en un periodo de cinco meses. El resultado de las evaluaciones agronómicas, demostraron que el comportamiento de las especies forrajeras introducidas, tanto gramíneas utilizadas como pasto de cobertura y de corte, así como leguminosas arbustivas utilizadas como cercos vivos; la evaluación nutricional en cuanto a materia seca (MS), fibra detergente neutra (FDN) y proteína total, efectuado a 120 días de la siembra no se encontraron diferencias significativas (p<0,05), en los SSP con cobertura de Brachiaria brizantha, demostrando que a esa edad de las pasturas todavía no se observan efectos de los cuatro diferentes sistemas evaluados; en las especies forrajeras introducidas en los SSP, se encontró una gran variabilidad en los índices nutricionales evaluados.
Dengue con signos de alarma
Authors: Rodríguez-Gómez Jorge Humberto
Published: July 2022

El objetivo de la investigación fue identificar las características clínicas del dengue con signos de alarma en pacientes hospitalizados, Hospital Tarapoto-MINSA. Se incorporaron 102 casos de dengue con signos de alarma internados en el Hospital de Tarapoto, durante los años 2011 al 2016; las definiciones fueron de casos oficiales para el Perú, los mismos que son recomendados por la OMS. El promedio de edad fue 30,2 ± 13,6 años; predominó el sexo masculino (58,8%); el 21,6% de casos acudió al hospital 2 o más veces antes de ser internados; la automedicación, se dio en el 68,63%; el tiempo de enfermedad para los signos de alarma fue de 4,13±1,6 días; fue más frecuente la fiebre (100%), artralgias y mialgias (66,7%), hiporexia (56,9%); los signos de alarma más frecuentes fueron dolor abdominal continuo e intenso (71,6%), sangrado externo (61,8%) y vómitos persistentes (49,0%); los hallazgos ecográficos fueron engrosamiento de pared vesicular, derrame pleural derecho y líquido en cavidad abdominal; al ingreso, el hematocrito fue 43,01% (DS ± 5,67) y a las 24 horas, 36,61% (DS ± 4,00).
Syphilis and pregnancy. Treatment Guidelines
Authors: Salazar Cañero María Fuensanta , Domínguez Mejías María , Gómez Díaz Marta Rosario
Published: July 2022

Introduction: Syphilis is a disease that presents clinical manifestations that can affect any organ causing serious health outcomes. Syphilis infection is transmitted mainly through sexual contact and vertical transmission. The probability of fetal involvement occurs in women with active syphilis infection, with inadequate or untreated infection acquired in the five years prior to pregnancy. Regarding treatment, although the effectiveness of penicillin in the treatment of syphilis in pregnant women and the prevention of congenital syphilis was established shortly after the introduction of penicillin in the 1940s, there is uncertainty about the optimal treatment regimens. Objective: To know the complications and treatment guidelines for syphilis during pregnancy. Methodology: We have carried out a bibliographic search on the treatment for the management of syphilis in pregnancy, but focusing on the doses and administration guidelines. For this, the search has been carried out in different databases: Cuiden, Pubmed, Cochrane, Scielo and Cuiden whose access has been made through the College of Nursing of Malaga. Results: the treatment of choice is penicillin administered intramuscularly. In case of allergy, erythromycin is used. Fetal complications can range from premature delivery or neonatal death. Conclusion: In today's world, health professionals must continuously raise awareness about sexually transmitted diseases, since they constitute a public health problem. In the case of pregnant women, especially professionals who work in this field to raise awareness, identify and treat syphilis to guarantee the health of women and newborns.
Fundamental signaling pathways for glioblastoma drug resistance and developing robust organoid models for drug discovery
Authors: Pratap Athira , Lim Eun-Jung , Kwak Ihn-Sil , Moon Byoung-San
Published: July 2022

This article presents a review of the current literature on the molecular mechanisms of treatment resistance in glioblastoma. As mounting research continues to explore novel methods of treating glioblastoma, from using organoid models for drug screening to developing novel cellular therapies, it is critical to understand the fundamental molecular landscape that makes glioblastoma difficult to treat. This review explores the means of chemoresistance to the conventional chemotherapy temozolomide. Consideration of DNA repair pathways, p53-mediated apoptosis and autophagy, convergent proliferation pathways, and epigenetic mechanisms demonstrate avenues for the development of sophisticated drug targets and combination treatments. Ultimately, this article highlights each of these mechanisms and presents referential material for future endeavors in organoid-based drug screening.
Akıllı ulaşım sistemleri (AUS) üzerine Türkiye’deki politikaların araştırılması
Authors: ÖZTAŞ KARLI Rukiye Gizem , ÇELİKYAY Hatice Selma
Published: July 2022

Ulaşımdan kaynaklanan sorunların çözümünü kolaylaştıran teknolojik gelişmeler ulaşım sektöründe itici bir güç olarak karşımıza çıkmaktadır. Her alanda değişim yaratan teknolojik gelişimler ulaşım alanında da yeni eğilimlere yol açarak ulaşım sistemlerinin daha güvenli, kaliteli, elverişli, ekonomik, çok modlu, çevreye duyarlı ve sürdürülebilir olması için çeşitli fırsatlar sunmaktadır. Bu durum, Akıllı Ulaşım Sistemi (AUS) kavramını ortaya çıkarmıştır. Dünya genelinde kentler rekabet edilebilirliğini artırmak ve sürdürülebilir kentsel ulaşım sistemleri oluşturabilmek için AUS’ye yönelik planlar ve projeler oluşturmakta, girişimlerde bulunmaktadır. Bu noktada Türkiye’nin de bu yarışa dahil olabilmesi için AUS’ye yönelik çalışmaların hız kazanması, plan, politika ve stratejilerin oluşturulması ve oluşturulan stratejiler çerçevesinde çalışmaların yapılması gerekmektedir. Öte yandan Türkiye’deki AUS’nin mevcut durumunu ortaya koyabilmek için geçmişten günümüze Türkiye’de oluşturulan politikaların incelenmesine ve gelişim sürecinin ortaya konulmasına ihtiyaç duyulmaktadır. Bu doğrultuda çalışmanın amacı günümüze kadar Türkiye’de oluşturulmuş politika metinlerinde AUS’nin gelişimini ortaya koymaktır. Politikalar, dokümantasyon analizi ile irdelenmiştir. Bulgular, Türkiye’de 2000’li yıllardan itibaren oluşturulan plan, politika ve strateji belgelerinde akıllı ulaşım sistemlerine altlık oluşturacak bazı hedeflerin geliştirildiğini ancak AUS’ye yönelik oluşturulan ilk planın 2014 yılında hazırlandığını ortaya koymaktadır. Son olarak bu çalışma ile Türkiye’nin AUS konusundaki mevcut durumu ortaya konularak politika yapıcılara ve ilgili tüm aktörlere faydalı olması hedeflenmektedir.
Criminological analysis of various categories of convicts in the process of considering the possibility of declaring an amnesty
Authors: Кохман Дмитрий Вадимович
Published: July 2022

В Российской Федерации высшие органы государственной власти многократно прибегали к изданию актов об амнистии. Последний был издан Государственной Думой Федерального Собрания Российской Федерации в 2015 году. Ежегодно обсуждается вопрос о возможности объявления новой амнистии. В связи с этим актуальными для современной криминологической науки становятся проблемы определения категорий потенциально амнистируемых лиц и мер, направленных на нивелирование негативных социальных последствий применения амнистии. Особого внимания заслуживает совокупность методов криминологического исследования, с помощью которых можно получить информацию, имеющую значение для разработки проекта акта об амнистии.

In the Russian Federation, the highest bodies of state power have repeatedly resorted to issuing acts of amnesty. The latter was published by the State Duma of the Federal Assembly of the Russian Federation in 2015. The question of the possibility of declaring a new amnesty is discussed annually. In this regard, the problems of determining the categories of potentially amnestied persons and measures aimed at leveling the negative social consequences of the application of amnesty are becoming relevant for modern criminological science. Special attention deserves a set of methods of criminological research, with the help of which it is possible to obtain information that is important for the development of a draft amnesty act.
Digitalization of everyday life and its cognitive-existential impact on a teenager: deviant socialization / normative socialization
Authors: Васильева Клавдия Кирилловна
Published: July 2022

В статье актуализируется бытие повседневности российского подростка через призму его пребывания либо в вещно-предметной реальности, либо в реальности виртуальной. Цель исследования - выявить причинные факторы формирования компьютерной зависимости у подростка. Результат исследования: интегральным показателем социализации современного подростка выступает степень цифровизации его повседневной жизни, а именно соотношение продолжительности времени пребывания в виртуальной и в невиртуальной реальностях. Установлено, что неконтролируемый фактор времени пребывания в виртуальной реальности формирует неоднозначную когнитивно-экзистенциальную и поведенческую направленность подростка. На уровне общем предполагается прямая зависимость количества времени пребывания подростка в виртуальной реальности и его потенциально отклоняющейся социализации как предпосылки девиантного поведения. Подчеркивается непосредственная, особо важная роль воздействия родителей и семьи на фактор времени пребывания подростка в виртуальной реальности и ее содержательной составляющей (контент) и, соответственно, на вектор и степень его социализации. Новизна: введено понятие «цифровизация повседневности» в значении нарушения меры времени пребывания в виртуальной реальности российскими подростками.

The article actualizes the everyday life of a Russian teenager through the prism of his stay either in the real-object reality or in the virtual reality. The purpose of the study is to identify the causal factors in the formation of computer addiction in adolescents. The result of the study: an integral indicator of the socialization of a modern teenager is the degree of digitalization of his daily life, namely the ratio of the length of time spent in virtual and non-virtual realities. It has been established that the uncontrolled factor of time spent in virtual reality forms an ambiguous cognitive-existential and behavioral orientation of a teenager. At the general level, a direct correlation is assumed between the amount of time a teenager spends in virtual reality and his potentially deviant socialization as a prerequisite for deviant behavior. The direct, especially important role of the influence of parents and family on the factor of time spent by a teenager in virtual reality and its content component (content) and, accordingly, on the vector and degree of his socialization is emphasized. Novelty: The concept of "digitalization of everyday life" has been introduced in the sense of violation of the measure of time spent in virtual reality by Russian teenagers.
Efficiency improving methods of the breeding work of the cynological service of the FPS of Russia
Authors: Попцова Ольга Сергеевна , Поносов Степан Владимирович
Published: July 2022

Организация ведомственного разведения собак служебных пород в условиях уголовно-исполнительной системы необходима для своевременного обеспечения кинологических подразделений служебными собаками. В связи с этим требуется максимально эффективно использовать имеющийся практический опыт разведения собак. В статье исследуется применение детектора течки для определения момента овуляции у собак. Путем наблюдения и эксперимента выявлено, что применение данного прибора демонстрирует высокую точность и эффективность в сравнении с традиционными методами. Возможно использование детектора течки в сочетании с лабораторно-диагностическими исследованиями или методом визуального наблюдения.

The organization of departmental breeding of dogs of service breeds in the conditions of the penitentiary system is necessary for the timely provision of cynological units with service dogs. In this regard, it is required to use the existing practical experience in breeding dogs as efficiently as possible. In this article the authors explore the use of an estrus detector to determine the time of ovulation in dogs. Through observation and experiment, it was found that the use of this device demonstrates high accuracy and efficiency in comparison with traditional methods. It is possible to use an estrus detector in combination with laboratory diagnostic studies or a visual observation method.
Main directions of prevention of involvement in the criminal subculture of employees of the criminal executive system
Authors: Пономарев Сергей Борисович , Пономарев Дмитрий Сергеевич , Полищук Вера Евгеньевна
Published: July 2022

На сегодняшний день криминальная (тюремная) субкультура становится одной из основных угроз, посягающих на разрушение аксиологической парадигмы традиционных гуманистических ценностей. По объективным причинам стратой-мишенью агрессивной экспансии тюремной субкультуры становятся сотрудники уголовно-исполнительной системы, которые в силу специфики своей работы вынуждены взаимодействовать с носителями этой субкультуры намного чаще, чем остальные граждане Российской Федерации. Целью работы является исследование основных направлений профилактики вовлеченности в криминальную субкультуру сотрудников уголовно-исполнительной системы. В качестве объекта исследования рассматривались особенности личности сотрудников уголовно-исполнительной системы. Предмет исследования - основные возможности и направления для профилактики и предотвращения вовлеченности в криминальную субкультуру сотрудников уголовно-исполнительной системы. Основными методами при проведении исследования явились методы теоретического уровня - формализация, аксиоматизация, гипотетико-дедуктивный метод.

Today, the criminal (prison) subculture is becoming one of the main threats encroaching on the destruction of the axiological paradigm of traditional humanistic values. For objective reasons, employees of the penitentiary system, who, due to the specifics of their work, are forced to interact with carriers of this subculture much more often than other citizens of the Russian Federation, become the target stratum of the aggressive expansion of the prison subculture. The aim of the work is to study the main areas of prevention of involvement in the criminal subculture of employees of the penitentiary system. As an object of study, the personality characteristics of employees of the penitentiary system were considered. The subject of the study is the main opportunities and directions for the prevention and prevention of the employees’ involvement in the criminal subculture of the penitentiary system. The main methods in the study were methods of the theoretical level - formalization, axiomatization, hypothetical-deductive method.
THE URGENCY OF IHSAN AND THINKING SYSTEMIC IN INCREASING MOTIVATION AND QUALITY OF EDUCATION
Authors: Azmi Ulil , Rosadi Kemas Imron , Zebua Ali Marzuki
Published: July 2022

The implementation of ihsan in life is very urgent, this is because ihsan will bring happiness in birth and mind. Systemic thinking will encourage something to produce according to expectations. This behavior can be realized by activating all kinds of elements that exist in an institution. The existence of Ihsan will make a person careful in acting and cultivate self-confidence from within while invoking divine rida, so as to increase motivation and quality in an educational institution. Systemic thinking requires motivation from the inside (intrinsic) and from the outside (extrinsic) to realize the components present in the systemic thinking device. So, the implementation of the Ihsan concept is very urgent to be applied to educational institutions. This can be applied through systemic thinking. So that in the end, with the realization of the concept of ihsan, it will provide motivation to institutions in thinking systemically to improve the quality of education. The purpose of writing this article is to build a hypothesis of influence between variables to be used in future research. The results of this study are 1) The urgency of Ihsan affects motivation; 2) Systemic Thinking affects Motivation ; 3) The urgency of Ihsan affects the Quality of Education 4) Thinking System affects the Quality of Education and 5) Motivation affects the Quality of Education.
PERBEDAAN LITERASI SAINS SISWA DALAM IMPLEMENTASI MODEL PEMBELAJARAN PROBLEM BASED LEARNING DAN PROJECT BASED LEARNING
Authors: AINI MAZIDAH QURROTU
Published: July 2022

The result of Scientific Literacy based on PISA, Indonesia are ranked far below other countries. Scientific literacy skills play an important role in shaping society to face Globalization. National education is one of the development sectors that aims to empower students. The aim of this research study is to determine the comparison of science literacy in implementation of problem-based learning model and project-based learning model on the concept of fungi. This research was conducted at SMAN 5 Depok of the academic year 2017/2018. The research methodology used Pre-experimental design through two groups pretest-posttest design. The sampling technique in this research was carried out purposive sampling technique and the sample was 36 tenth-grade students of MIPA 1 and 37 tenth-grade students of MIPA 5 that involved in this research. The instrument test were an essays test consisting of ten questions and scientific performance attitude sheet. The data analysis of both groups was examined by using t-test. The obtained result is t-count 3,030 over t-table 1,993 (Sig 3,030 > 1,993) with 5% significance. The data showed that there were some differences in science literacy between students using problem-based learning model and project-based learning model on the concept of fungi. The conclusion is problem based learning more effective to enhance science literacy on the concept of fungi in comparison to project based learning
ABSTRAKKemampuan literasi sains berperan penting dalam pembentukan masyarakat untuk menghadapi era globalisasi saat ini. Pendidikan nasional merupakan salah satu sektor pembangunan yang bertujuan untuk memperdayakan masyarakat. Penelitian ini bertujuan untuk mengetahui perbedaan literasi sains siswa dalam implementasi model pembelajaran berbasis masalah (problem based learning) dan Pembelajaran Berbasis Proyek (project based learning) pada konsep Fungi. Penelitian ini dilakukan di SMA Negeri 5 Depok Tahun Pelajaran 2017/2018. Metode penelitian yang digunakan adalah Pre-Experimental design yang menggunakan  desain penelitian two groups pretest-posttest design. Pengambilan sampel dalam penelitian ini menggunakan teknik purposive sampling. Sampel penelitian ini adalah siswa kelas X MIPA 1 berjumlah 36 orang dan siswa kelas X MIPA 5 berjumlah 37 orang. Instrumen penelitian yang digunakan berupa tes uraian dan lembar observasi kinerja ilmiah. Analisis data kedua kelompok dilakukan dengan menggunakan uji-t. Hasil yang diperoleh adalah t hitung sebesar 3,030 lebih besar dari t tabel sebesar 1,993 (Sig 3,030 > 1,993) dengan taraf signifikansi 5%. Hal ini menunjukkan terdapat perbedaan literasi sains siswa dalam implementasi model pembelajaran berbasis masalah dan pembelajaran berbasis proyek pada konsep fungi. Kesimpulan dari hasil penelitian adalah pembelajaran berbasis masalah dapat meningkatkan literasi sains lebih baik daripada pembelajaran berbasis proyek.
PENINGKATAN KEMAMPUAN BERPIKIR KRITIS DAN NILAI-NILAI KEARIFAN LOKAL MELALUI PENERAPAN MODEL PROBLEM BASED LEARNING DALAM PEMBELAJARAN SEJARAH SISWA KELAS X. 1 TEKNIK AUDIO VIDEO SMK NEGERI 2 BAUBAU SEMESTER GANJIL TAHUN PELAJARAN 2019/2020
Authors: ZARMIN LAODE
Published: July 2022

Based on the results of the first cycle, classical completeness critical thinking skills of students by 74.07% with an average value of grade 76, second cycle of 92.59% with an average value of grade 78 and the third cycle reaches 96.15% with average value of grade 82. The results of these studies noted an increase in critical thinking skills and the achievement of classical completeness. Based on the questionnaire cycle I, II and III data showed percentage of students’ local wisdom values respectively by 96.30%, 100% and 100% the third cycle. Class average poll result shows: the first cycle of 85.73, the second cycle of 89.53 and the third cycle of 93.43. From the result of class action research it can be concluded that the application of problem-based learning model in class X.1 Teknik Audio Video of SMK Negeri 2 Baubau can improve critical thinking skills and students’ local wisdom values.
ABSTRAKBerdasarkan hasil siklus pertama, kelengkapan kritis keterampilan berpikir klasik siswa dengan 74,07% dengan nilai rata-rata kelas 76, siklus II 92,59% dengan nilai rata-rata kelas 78 dan siklus ketiga mencapai 96,15% dengan nilai rata-rata kelas 82. hasil studi ini mencatat peningkatan keterampilan berpikir kritis dan pencapaian ketuntasan klasikal. Berdasarkan siklus kuesioner I, II dan III data menunjukkan persentase nilai kearifan lokal siswa masing-masing sebesar 96,30%, 100% dan 100% pada siklus III. Kelas hasil jajak pendapat menunjukkan rata-rata: siklus pertama 85,73, siklus II 89,53 dan siklus III 93,43. Dari hasil penelitian tindakan kelas dapat disimpulkan bahwa penerapan model pembelajaran berbasis masalah dalam kelas X.1 Teknik Audio Video SMK Negeri 2 Baubau dapat meningkatkan keterampilan berpikir kritis dan nilai-nilai kearifan lokal siswa.
What was Killing Babies in Hermoupolis, Greece? An Investigation of Infant Mortality Using Individual Level Causes of Death, 1861–1930
Authors: Raftakis Michail
Published: July 2022

This paper employs individual level cause of death data from the port city of Hermoupolis on the Greek island of Syros, in order to test the newly-constructed ICD10h coding system. By constructing cause specific death rates for infants from the late 19th century to early 20th century, the paper contributes to a comparative approach, which aims to show how causes of death differ across several locations within Europe and how they develop over time. Given the scarcity of cause of death data both at the individual and aggregate level in Greece roughly prior to the 1920s, the availability of such data in the draft death registers (for sporadic runs of years in the second half of the 19th and early 20th century) and the civil registration (from 1916 onwards) in Hermoupolis provides a deeper understanding of the history of cause-of-death reporting in the country. Infant mortality in Hermoupolis was relatively high throughout the study period, with water-food borne diseases accounting for the highest number of infant deaths, especially during the hot and dry summer months. While the prominent winter peak of neonatal mortality but also congenital-birth disorders could be partially associated with birth seasonality and/or low temperatures over the winter months. Finally, certain vague terms such as 'atrophy' and 'athrepsy', but especially 'drakos' require further investigation until they are firmly understood.
O uso de bioestimuladores de colágeno a base de hidroxiapatita de cálcio
Authors: Neca Cinthia Silva Moura , Gondim Ana Carolina Luiz , Rocha Carolina Aparecida Silva , Silva Cleusa Aparecida Pereira , Silva Flávia Gomes da
Published: July 2022

A aparência facial e os sinais visíveis do envelhecimento estão diretamente ligados a ação muscular, flacidez da pele, perda da sustentação óssea e diminuição do volume dos compartimentos de gordura faciais. O processo de envelhecimento pode ser acelerado por alguns fatores internos e externos , como o sol, e até mesmo alguns alimentos. Neste trabalho de revisão de literatura a ideia é conhecer os bioestimuladores de colágeno identificados como hidroxiapatita de cálcio (CaHA) em suas características fundamentais, suas indicações e funcionamento no organismo. Houve um levantamento bibliográfico nas bases SciELO, PubMed e Google Acadêmico por artigos publicados entre os anos 2018 a 2022. Conforme a literatura, todos os preenchedores cutâneos são considerados eficazes e seguros, podendo ser utilizados por profissionais devidamente capacitados.
Արցախի Հանրապետության միգրացիոն իրավիճակի համապարփակ վերլուծություն/ Comprehensive Analysis of the Migration Situation of the
Republic of Artsakh
Authors: VARDANYAN TATEVIK , MIKAYELYAN TIGRAN
Published: July 2022

The main purpose of the paper is to
assess the migration processes in Artsakh in a demographic
context. The main objective of the research is to conduct a
comprehensive analysis of the migration situation in Artsakh as a
result of studying and analyzing the de jure population of Artsakh
and Armenia, as well as the annual population growth rate, natural
and mechanical growth, the number of people arriving and
leaving Artsakh. In this context, through the methods of analyzing
historical series, comparative analysis, the authors presented the
migration processes in Artsakh, combining them with the
processes taking place in the demographic situation. The
movement of the population of Artsakh and Armenia has shown
that the rate of annual de jure population growth in Artsakh is
higher than in Armenia. Moreover, the same can be recorded for
both natural and mechanical growth indicators. In general, the
analysis of the migration situation in Artsakh shows that the causes
and consequences of migration have changed over the years. The
last, most significant factor is the 44-day war unleashed by
Azerbaijan on September 27, 2020, the influence of which on the
migration propensity of the Artsakh people continues to this day.
Հարկաբյուջետային քաղաքականության ազդեցությունը բնակչության եկամուտների անհավասարության վրա Հայաստանի Հանրապետությունում/Impact of Fiscal Policy on Income Inequality in the
Republic of Armenia.
Authors: AVAGYAN GAYANE , TOROSYAN ALIK
Published: July 2022

Income inequality is characteristic of all
economic systems. The market mechanism of income
redistribution, and even their centralized regulation, can not
eliminate this inequality, because equal distribution of income
does not only lead to social justice, but also weakens incentives to
work and the desire to ensure high productivity. Moreover,
differences in ability, education and training, professional taste
and risk, ownership of property are significant factors in the
emergence of income inequality in society. The paper analyzes the
impact of fiscal policy on overcoming income inequality. For this
purpose, first researches done by different economists in this field
were commented, then the current state of income inequality in
Armenia, the changes of the fiscal policy during the last decade
were studied. A model has been developed to assess the impact of
fiscal policy on income inequality, the future course of certain
fiscal policy instruments, their impact on income inequality for the
next five years.
West Syndrome: A Case Study Through Audiological Perspective
Authors: Mohan Vishnu
Published: July 2022

West Syndrome is a disorder with combination of symptoms such as infantile spasm along with its typical age of onset and specific kind of electroencephalogram pattern termed as hypsarrhythmia Here in this article I report a case of West syndrome with left hemi paresis, diagnosed in a 2.5 year old baby boy

Key words: West Syndrome, Hearing Evaluation, Auditory brainstem response .
De Quervain’s Tenosynovitis with Homoeopathic Treatment in Middle-aged People: Case Report
Authors: Das Shimul , Das Abhinandan
Published: July 2022

Introduction: - De Quervain’s tenosynovitis (DQT) is a painful condition mainly affecting the thumbs or radial side of the wrist joints. Treating with homoeopathic medicines, patients get relief from this painful condition.
Case Summary: - A Hindu lady age 46 years, a housewife, who belongs to a middle-class society complained of pain in the wrist joint & Duration of pain was about 4-5-month. Her location was moved to the rt. thumb. & Her sensation was Drawing/Tearing. All pain was aggravated by caring heavy wait but relief in hand activities and cold applications. Amelioration by Warm application & Massage.
The aim was to show that homoeopathy can treat DQT. Also demonstrates the utility of single and minimum doses in homoeopathy.

Key words: Abductor Pollicis Longus, De Quervain’s Tenosynovitis, Extensor, Finkelstein’s test, Homoeopathy, Kent Observation, Pollicis Brevis.
Opsoclonus Myoclonus due to Phenytoin Toxicity
Authors: Gharsangi Komal , . Parul
Published: July 2022

Phenytoin is one of the oldest and commonest antiepileptic drugs used in our country. It is known for its toxicity as neurological and cardiac manifestations. Opsoclonus myoclonus syndrome due to phenytoin toxicity is a rare incidence. We report a case of phenytoin toxicity in 18 year female patient who was taking phenytoin for symptomatic generalized tonic clonic seizures 1month back who now presented with opsoclonus, myoclonus and truncal ataxia.

Key words: Phenytoin toxicity, opsoclonus, myoclonus.
Effect of Static Stretching on Random Blood Sugar Levels in Type 2 Diabetes Mellitus: A Randomized Clinical Trial
Authors: Shirodkar Dr. Sridhar , Deo Dr. Medha , Agnihotri Dr. Manoj
Published: July 2022

According to the International Diabetes Federation's Diabetes Atlas 2006, the number of diabetics will top 70 million by next mid-decade. Type I and type II are the two variations diabetes that exist. 90-95% of diabetics have type 2 DM. Recent studies have shown that exercise and physical activity reduce blood sugar levels. Yoga, aerobics, swimming, stretching, and resistance training improve insulin sensitivity. As type II diabetes can cause neuropathies, hypertension, and amputations, static stretching may help those who can't do regular exercise. People who have been bedridden for a long time or who are too old to do other types of exercise may benefit from static stretching. Earlier research was done to compare the immediate effects of static stretching vs. resistance exercises on blood sugar levels after a meal in people with type II diabetes mellitus. Long-term consequences of static stretching on type II diabetes unpredictable blood sugar levels are unknown. This study examined the effect of static stretching on type II diabetics' random blood sugar levels.

Key words: Diabetes, Stretching, exercises, aerobic exercise, blood glucose level..
Concept of Inutero and Infantile Psychological Development in Ayurveda
Authors: Kumari Jangir Dr. Jyoti , Kumar K. Dr. Shrinidhi
Published: July 2022

Ayurveda is a rich medical heritage of India which believes in global approach while dealing with individuals’ effort for building the high-quality psychological status begins with preconceptional period itself by strictly following certain rules of celibacy and dietary regimen. Later after conception during first trimester in which fetus is undifferentiated and during the process of differentiation emotional and psychological status of pregnant lady play a vital role and rightly certain rules regulations, daily regimens were explained to keep the mother stress level at base mining level. Concept of endowment of the fetus and development of ID and Ego in fetal stage with its differentiation into Satvika, Rajasika, and Tamasika status has been well explained in Ayurveda. Further outcome of psychological status a fetus with existing internal and external uterine environment (Satmya) also plays a major role. After birth there will be development of Ego and Superego to produce psychologically, morally, and emotionally fit child in future has been well explained in Ayurveda.

Key words: Growth and development, Personality development, Samskaras, Developmental delay, psychoanalysis theory, Id, Ego and Superego.
PENGARUH SISTEM PELAYANAN, KUALITAS PRODUK TERHADAP PENINGKATAN PENJUALAN DI RESTORAN CEPAT SAJI BURGER KING
Authors: ERISKA ERISKA RINDIYANI , Anita Kartika Sari  , Lukman Nuzul Hakim
Published: July 2022

The motivation behind this exploration is to figure out that of the MAP GROUP, namely Burger King Tunjungan Plaza 1 Surabaya, which is known as BK is probably the biggest establishment on the world. The examination strategy utilized isqualitative, which means using the condition of the object naturally. The focus of the researcher is then described according to the applicable rules. The objects in this study are how influential the service system and product quality are to sales at every operating hour of the restaurant open to closing, as well as a survey of consumers who are willing to provide an assessment through the official website with satisfactory results regarding product quality and service every time they visit Burger King Surabaya.
Phytochemical Screening of Putat Air [Barringtonia racemosa (L.)] Spreng Herbal Plants Found in Bireun, Aceh, Indonesia
Authors: Asnah Sitohang Nur , De lux Putra Effendy , Kamil Hajjul , Musman Musri
Published: July 2022

Indonesia has a variety of medicinal plants. This medicinal plant has been widely used by the public in an effort to overcome health problems such as wound healing amid advances in science and technology. The discovery of various new medicinal compounds from natural materials further clarifies the important role of secondary metabolites of plants as medicinal raw materials. A natural ingredient that can be used as an alternative biological therapy for wound management is the putat air [Barringtonia racemosa (L.) Spreng.]. This plant is found in Gampong Pulo village, District of Peudada Bireun Regency, Aceh Province, Indonesia. B. racemosa is a type of local mangrove plant known as putat air. It grows wild along the banks of rivers, lakes and rice fields. Phytochemical screening results with Shinoda test of B. racemosa seeds in ethanol extract, ethyl acetate fraction and water containing flavonoids. Molisch test on ethanol extract, fraction of ethyl acetate and water containing glycosides. Foam test on ethanol extract, hexan fraction, ethyl acetate fraction and water fraction detected saponins. Using iron reaxation (III) chloride on ethanol extract and water fraction contains tannins Liebermann-Burchard test on fraction n – hexants containing steroids and triterpenoids. As the conclusion, B. racemosa seeds contain many secondary metabolites that can be used by the public as an alternative treatment of the disease.
UV Spectrophotometric Method Development and Validation for the Determination of Ascorbyl Palmitate in Bulk and its Pharmaceutical Dosage Form
Authors: Prudhvinath G. , Prashanthi B. , Chary V. Padmabhushana , Eswaraiah M. Chinna , Shivani G.
Published: July 2022

A simple, economical, accurate, precise and less time-consuming UV spectrophotometric method has been developed and validated for estimation of Ascorbyl palmitate in bulk and pharmaceutical formulations. In this method, Ascorbyl palmitate exhibits maximum absorbance (λ max) at 261nm. The drug obeys Beer’s law in the concentration range of 2-12μg/ml. The method was validated as per the International Conference on Harmonization (ICH) guidelines. Drug followed the linearity in the concentration range of 2-12μg/ml with correlation coefficient (R2) of 0.998. The validity of the proposed method was assessed by applying the standard addition technique where the percentage recovery of the added standard was found to be 100% -109.7%. The limit of detection and quantification were calculated to be 0.1200µg/ml and 0.363μg/ml respectively. The proposed method is recommended for routine analysis of Ascorbyl palmitate in bulk and dosage forms in quality control testing laboratories. Since it is rapid, simple, accurate, sensitive and economical.
Systematic Review on Phytochemistry and Pharmacology Studies of Alangium salvifolium
Authors: Fattepur Santosh , Kumar Sahu Ram , Singh Jangdey Manmohan , Sreeharsha Nagaraja , Chanabasappa Nilugal Kiran , Abdullah Ibrahim , Sharma Uttam , Biswal Jayshreemaa , Rani Bhuyan Jochhana
Published: July 2022

Alangium salvifolium is considered a medicinal plant in India and is used to heal various diseases. The traditional healers documented that roots, leaves, flowers, fruits, stems, and bark of Alangium salvifolium have potent medicinal properties. The researchers reported the nature of the phytoconstituents responsible for imparting therapeutic properties. Different pharmacological actions such as antidiabetic, anti-ulcer, anticancer, anticonvulsant, anti-inflammatory, analgesic, antiarthritis, antimicrobial, anthelmintics, cardioprotective, hepatoprotective, etc. have been scientifically investigated based on the chemical constituents of this plant. Further, the biomarkers compounds are isolated and characterized, which are responsible for the therapeutic efficacy. The present paper presented the phytochemistry and pharmacological activities of Alangium salvifolium. The researchers have enormous scope to explore the unidentified active constituents, preclinical and clinical study of the different parts of Alangium salvifolium.
EPIDEMIOLOGICAL AND CLINICAL PARAMETERS IN PATIENTS WITH COVID-19 AND BRONCHIAL ASTHMA
Authors:   Clinic of Pneumology and Phthisiatry, Medical University, Pleven, Bulgaria., Glogovska Pavlina , Gospodinov Konstantin ,   First Cardiology Clinic, Medical University, Pleven, Bulgaria., Pavlov Plamen ,   Clinic of Pneumology and Phthisiatry, Medical University, Pleven, Bulgaria., Borisova Elena ,   Clinic of Pneumology and Phthisiatry, Medical University, Pleven, Bulgaria.
Published: July 2022

Purpose: to analyze the epidemiological and clinical parameters of asthmatic patients with COVID-19 infection. Materials and methods: a retrospective study was performed including data from an outpatient pulmonary practice in Pleven, Bulgaria, for the period 01.04. 2020 – 31.12. 2021. Sixty-five asthmatics were included and divided into two groups, referred to hospital due to COVID-19 infection (A) and outpatients (B), and their epidemiological and clinical data were compared. Results: 65 patients were analyzed, 46 (71%) women and 19 (29%) men. Forty-four patients were confirmed with PCR and/or antigen test, and in 21, the diagnosis was based on clinical and X-ray data. Group A included 18 patients. It was found that patients over 65 years were significantly more in group A (44.4% vs 18.8%, p<0.05). There were significant differences between the groups concerning ischemic heart disease (9%/3%, p=0.001), arterial hypertension (10.6%/7.6%, p=0.007), heart failure (3%/0%, p=0.01), diabetes, but not in allergic rhinitis. We did not find a distinction regarding sex, adherence to inhalation therapy and usage of systemic corticosteroids (p>0.05). None of the patients had an exacerbation during the treatment in the hospital and within a month after the hospital discharge. Conclusion: According to the analyses of the study, COVID-19 infection is not a risk factor for asthma exacerbations. The leading causes for the severity of the coronavirus infection in asthmatics are the age and some concomitant diseases.
Retrospective application and validation of Tokyo 18 guidelines for diagnosis and stratification of acute cholangitis in Qatar
Authors: Said Ghali Mohamed , Al-Yahri Omer , Al Dhaheri Mahmood , Ali Shah Amjad , Toffaha Ali , Singh Rajvir , Zarour Ahmad
Published: July 2022

Background: Acute cholangitis (AC) is a life-threatening condition with a mortality risk of 8%–10%. Despite no gold standard for diagnosis, Charcot's triad was introduced to diagnose AC. However, the triad had a low sensitivity (50%–70%). Recently, Tokyo guidelines (TG) for the diagnosis of AC gained international recognition for their excellent diagnostic rate. Objective: In this study, we aimed to apply TG18 guidelines in a retrospective manner to diagnose AC in Qatar to validate TG18. Methods: This retrospective observational study recruited 295 patients with clinically proven AC between January 2016 and July 2018. Results: Of the 213 patients, 72.2% were men. The mean age was 51.4 ± 17.5 years. The most common co-morbidity was hypertension (36.3%). Common bile duct stones were the most common cause of biliary obstruction found in 165 (55.9%) patients. The diagnostic rate of TG18 was 91.9% in contrast to Charcot's triad (34.9%). By TG18 grading, 150 (50.8%) patients were grade I. ERCP was done in 62% patients, and 52.5% of them were grade I. Conclusion: AC management in Qatar meets the international standards with a low mortality rate. TG18 guidelines had a high diagnostic rate among our patient population.
Influência do consumo de probióticos e prebióticos na prevenção e tratamento de disbiose
Authors: Nascimento-Silva Nara Rúbia , Silva Lucas Luiz , Santos Cleidilene , Gama Aline
Published: July 2022

O desequilíbrio da microbiota intestinal pode gerar inflamação crônica, evasão imune e outras patologias intra e extraintestinais. Na prevenção e tratamento de disbiose, destacam-se os pro e prebióticos.  Esta revisão objetiva avaliar a influência do consumo destes alimentos no tratamento e prevenção de disbiose. A principal maneira de tratar a disbiose é abstinência de certos alimentos da dieta e o uso de alimentos funcionais. A ingestão dietética de frutanos aumentam as bifidobactérias intestinais e exercem um efeito protetor contra endotoxemia. A ligação de bactérias probióticas aos receptores dos enterócitos dá início à cascata de reações imunológicas. As Bifidobactérias, galactooligossacarídeos, frutooligossacarídeos e os Lactobacillus tem a capacidade de reequilibrar a microbiota por provocar uma melhora na implantação e na sobrevivência dos micro-organismos benéficos. O papel direto e indireto dos micro-organismos pré e probióticos propiciam uma microbiota intestinal saudável e equilibrada ao hospedeiro.
An in-vitro comparative evaluation for detection of residual gutta-percha after root canal retreatment with four different files using stereo microscope
Authors: Rathod R. Tejasree , Poreddy Satyanarayana Reddy , Poreddy Satyanarayana Reddy , Durgabhavani G. , Gonapa Prasanthi , Thodsam Gopal , Prasad B. Rajendra
Published: July 2022

Background: Removal of gutta-percha using hand files with or without solvent is tedious and time consuming process especially when the root filling material is well compacted8. Therefore, the use of NiTi rotary instruments in the root canal retreatment might decrease patient and operator fatigue and various studies have reported their efficacy, cleaning ability and safety. Several NiTi rotary instruments also were been used to remove gutta-percha. Here in this study four file systems were used to assess the efficacy of each file system in retreatment procedures.Materials & methods: The study samples comprised of 80 extracted anteriors having single root canals with fully formed apices were collected. The crowns were de-coronated with a diamond disc to leave a 16-mm root. A size 10 K-file was introduced into the canal until it was visible at the apical foramen. The working length was determined by subtracting 1mm from this measurement. During shaping, each canal was irrigated with 3% sodium hypochlorite then smear layer was removed with 17% EDTA and 1 ml of 3% sodium hypochlorite. After one month the teeth were divided into following groups with 20 specimens each as follows.
Ruwatan Murwakala on religious and cultural perspective
Authors: Maryano Maryano , Triguna Ida Bagus Gde Yudha , Utama I Wayan Budi
Published: July 2022

Ruwatan is a Javanese tradition that is still practiced by Javanese in general, although many people from certain religions think it is contradictory, which was previously carried out in order to improve social status, usually done in rural areas, only people who have financial ability, but in reality it is a purification of the soul, a cultural activity, carried out in a metropolitan city, carried out by all groups. Research with qualitative research approach that is descriptive which tends to use analysis, process and meaning supported by the phenomenological theory, the theory of religion and the theory of The Rites Of Passage. The results showed that the ruwatan tradition was passed down from generation to generation and still has an important position and needs to be uri-uri, enthusiastically welcomed from all groups, ethnicities, and religions, a mystical touch on the spiritual aspect of ruwatan, phenomenology interprets their experiences and understands the world with their personal experiences. The implementation of ruwatan murwakala is still being carried out, because rituals that are contrary to certain religions are eliminated without changing their essence, cultural values ​​become community guidelines to act in dealing with various life problems, art businesses emerge.
Gender differences in adolescent self-harming behaviour
Authors: Demuth Andrej , Demuthova Slavka
Published: July 2022

The occurrence of self-harming behaviour as a non-adaptive coping strategy within the adolescent population is on the increase. In an effort to clarify the occurrence and characteristics of this high-risk behaviour, many experts have focused on an examination of the various variables related to the prevalence, risk, or protective factors of self-harm. Many studies have focused on gender differences; however, the results have been mixed. The study provides basic data on the incidence of self-harm in a group of male and female (N = 1699) adolescents (11-19 years, AM = 15.24). Through an analysis of the differences in prevalence, intensity, and types of self-harming behaviour, related to gender, it tries to identify the reasons for the different findings in the published literature. The results show that although the prevalence and overall intensity of self-harm is statistically higher in women, this does not apply to the most frequently studied direct physical forms of self-harm. Through its findings, the study draws attention to the need for a clear definition of self-harm as well as to the consequences of different diagnostic approaches.
socioeconomic status of girls and boys relating to their psychological health
Authors: Al-Hendawi Maha , Nasser Ramzi N
Published: July 2022

Socioeconomic status is an important exogenous factor impacting the child’s psychology and well-being.  Participants in this study included students from grades 8, 10, 11, and 12 from Qatar. To measure emotional and behavioral problems, the students completed self-report questionnaires on socioeconomic indicators, gender, age, and the Strengths and Difficulties Questionnaire. Confirmatory factor analysis was performed, and the model was improved by removing poorly loaded items. ANOVA was performed using an improved version of the model. The highest means were for emotional problems. The adolescents were mostly normal across all domains of the emotional and behavioral problem dimensions. In the univariate analysis, socioeconomic status was inversely related to all emotional and behavioral problem domains. The higher socioeconomic status the lower the emotional and behavioral problems. Girls had higher levels of emotional and behavioral problems, specifically related to emotional domains. There were no interaction effects between gender and socioeconomic status. The main significant differences found between males and females on emotional problems.  In addition, a mean difference between high and average socioeconomic status on emotional problems was found. Similarly, there was a significant difference found between high economic status and middle and low socioeconomic status for peer problems.