bluuebunny/crossref_metadata_2025 huggingface dataset:
Elena Fortún en "Oculto sendero", la posibilidad de un testimonio
Authors: Gallardo Sara R.
Published: July 2023

Este trabajo pretende analizar la novela autobiográfica Oculto sendero (2016) de Elena Fortún como un testimonio fundamental de la historia LGTBI+ en España. Para llevar a cabo esta investigación, proponemos un análisis materialista de la diégesis y de los contextos con los que se relaciona: el de los hechos relatados, el del tiempo de escritura, es decir, cuando la autora pudo por fin comenzar a elaborar su relato, y el actual, en el que por fin se hace pública su historia. Esa recepción permite que se produzca el verdadero testimonio: solo es posible cuando su reconocimiento como lesbiana ha encontrado recepción y asilo. La construcción de la identidad será estudiada desde sus distintas vertientes: como mujer, como mujer que escribe en la primera mitad del siglo XX español, como lesbiana, como sujeto subalterno y como escritora que expresa su disidencia de género a través de la narración, oculta y revelada, de distintas experiencias y declaraciones que trataremos de categorizar.
Testimonios (im)políticos. Las huellas sonoras del 15M
Authors: Gil Escribano Miguel Ángel
Published: July 2023

El presente artículo tiene como objetivo presentar una análisis del acontecimiento del 15M desde las músicas que sonaron durante la manifestación y la acampada, a modo de huellas sonoras que hoy nos quedan, en calidad de testimonios de aquella experiencia así como de sus reclamos políticos. Se propone realizar por tanto una “escucha epistemológica” del soundscape, atendiendo a lo que de performativo tuvo esa producción sonora, hasta descifrar las audiotopías que han quedado registradas. Todo ello nos lleva a proponer que aquel acontecimiento, desde su registro sonoro, emergió en la calidad de un impolítico que desbordó los márgenes sociales y políticos heredados de la Transición a la democracia.
Edición y censura en la narrativa testimonial sobre los campos de concentración franceses publicada en España a finales del franquismo
Authors: Simón Porolli Paula Cecilia
Published: July 2023

El artículo se propone hacer un aporte al estudio del testimonio en España a partir de la consideración de dos volúmenes pertenecientes al corpus de la narrativa testimonial sobre el éxodo de 1939, los campos de concentración franceses y la salida al exilio, escritas por dos autores supervivientes de dichas experiencias, Avel•lí Artís-Gener y José Bort-Vela. Sus dos obras, La diáspora republicana (1975) y La angustia de vivir (1977), publicadas durante el denominado “tardofranquismo” y el período de la transición democrática respectivamente, demuestran una persistente tensión entre dos fuerzas que pujan por el sentido: por un lado, la impulsada por autores y editores, representantes del colectivo republicano, quienes intentan restablecer su propia versión sobre el pasado de la guerra y los campos; y por el otro, la fuerza del Régimen franquista, representada por la institución de la censura, que hasta último momento impuso su control y sus reglas conservadoras para reproducir una retórica que lo desmarcara de sus responsabilidades frente al destino de los exiliados o bien, que acentuara su derrota.
“Relato esto para los que están lejos del rigor que ha sido nuestra clandestinidad”: mujeres y lucha clandestina contra el franquismo en la obra testimonial de Tomasa Cuevas
Authors: Somolinos Molina Cristina
Published: July 2023

Los tres volúmenes de testimonios editados por Tomasa Cuevas —Cárcel de mujeres (1939-1945) (1985); Cárcel de mujeres: Ventas, Segovia, Les Corts (1985); y Mujeres de la resistencia (1986)— recogen, principalmente, las experiencias de militantes antifranquistas en su paso por las prisiones de mujeres del régimen. Sin embargo, esta no es la única experiencia de la represión (y, en relación con ello, de la resistencia) que se encuentra en los relatos, pues ellas mismas hacen referencia en sus testimonios a las numerosas tareas y actividades que realizaron en la lucha clandestina contra el franquismo. En este trabajo, me propongo analizar las modalidades de la lucha clandestina que aparecen en los relatos testimoniales recogidos por Cuevas, de entre las que destaca la reorganización del Partido en la clandestinidad, la solidaridad y el apoyo a presos y a las guerrillas y la realización de tareas de apoyo, en especial en relación con el mantenimiento y organización del aparato de propaganda, así como la difusión de prensa clandestina. Se considerarán asimismo las dimensiones textuales específicas de las narrativas testimoniales publicadas en estos volúmenes y las particularidades que presenta la mediación de Cuevas como compiladora de estos testimonios, así como su inserción en los marcos de debate contemporáneos a su publicación y difusión.
Cuerpos híbridos: especie, género y carne en la narrativa breve española contemporánea
Authors: Pallardó Azorín Betlem
Published: July 2023

En los últimos años, asistimos a una proliferación de ficciones en que se refleja un creciente interés social por visibilizar violencias normalizadas e invisibilizadas. Entre estas violencias, una de las más arraigadas en nuestra sociedad es la que supone la “cultura de la carne” (Potts, 2016), que afecta a los animales no humanos. Este artículo, que se enmarca en una investigación amplia en torno a los mecanismos empleados en la narrativa breve española contemporánea para desestabilizar el binomio vida política / vida fisiológica y así cuestionar la cultura de la carne, se centra en las figuras híbridas humanimales. En concreto, se estudian dos relatos en que un cuerpo simultáneamente (animal) humano y (animal) no humano es consumido: la sirena en “Los frutos del mar” (2018), de José María Merino, y la cecaelia en “Espuma de color lavanda” (2019), de Covadonga González-Pola. A partir de las ideas de figuras como Carol Adams, Derrida, Haraway o Agamben, se analizan estas ficciones como espacios de resistencia frente a los discursos hegemónicos que naturalizan la violencia de la cultura de la carne. Además, puesto que la parte humana de los cuerpos híbridos es femenina, se estudian los vínculos entre la violencia patriarcal y la especista a los que apuntan las ficciones.
Effects of extracts from various parts of invasive Solidago species on the germination and growth of native grassland plant species
Authors: Perera Peliyagodage Chathura Dineth , Chmielowiec Cezary , Szymura Tomasz H. , Szymura Magdalena
Published: July 2023

Allelopathy is an important factor influencing whether an invasive plant species can become successfully established in a new range through disrupting the germination and growth of native plant species. Goldenrods (Solidago species) are one of the most widespread invasive taxa in Central Europe of North American origin. Owing to their high environmental impact and wide distribution range, invasive Solidago species should be controlled in Europe, and the areas invaded by them should be restored. Numerous studies have reported the allelopathic effects of Solidago gigantea and Solidago canadensis, but the results are inconsistent regarding differences in the allelopathic effects of particular plant parts and in the sensitivity to Solidago allelopathic effects among native species as well as between the two invasive species themselves. In this study, we aimed to analyse the effect of water extracts from S. canadensis and S. gigantea parts (roots, rhizomes, stems, leaves, and inflorescences) on the germination and initial growth of seedlings of 13 grassland species that typically grow in Central Europe. The tested grassland species differed in susceptibility to Solidago allelopathy, with the most resistant species being Schedonorus pratensis, Lolium perenne, Trifolium pratense, Daucus carota and Leucanthemum vulgare. The inhibitory effect of 10% water extracts from leaves and flowers were stronger than those from rhizomes, roots, and stems without leaves, regardless of the Solidago species. Our study results imply that reducing the allelopathic effect of Solidago during habitat restoration requires removal of the aboveground parts, including fallen leaves. The allelopathic effects of roots and rhizomes seem to be of secondary importance.
Qualidade 4.0: tecnologias emergentes e suas aplicações
Authors: Da Silva Celso Willians Bandeira , Nascimento Jheymerson Silva , Ferraz Mário Andrey , Roberto José Carlos Alves , Soares Maisa Caxias
Published: July 2023

O ambiente tecnológico promissor, moldado pela emergência de avanços sem precedentes, tais como a inteligência artificial, está reformulando profundamente o mundo, assim como o âmbito dos negócios. Nesse contexto, a gestão da qualidade surge como um campo em evidência devido ao seu potencial para revolucionar práticas industriais por meio da Qualidade 4.0, uma abordagem inovadora que combina tecnologia e digitalização no cenário da Indústria 4.0. Diante deste contexto, esta pesquisa tem como problemática: qual será o impacto de tecnologias digitais ​​no controle de qualidade e como ela afetará a eficiência e a eficácia dos processos de produção e serviço?  O objetivo geral é explicar o impacto da implementação da qualidade 4.0, com foco particular em como as ferramentas tecnológicas da indústria 4.0 podem ser usadas para elevar ao máximo a eficiência e a eficácia dos controles de qualidade produtivo. Adotou-se uma pesquisa de natureza básica e qualitativa, de caráter explicativo, apoiada em revisão bibliográfica para compilar e analisar conhecimentos disponíveis na literatura científica sobre o tema. Este estudo esclarece a contribuição significativa da Qualidade 4.0 na gestão da qualidade, unindo ferramentas tecnológicas da Indústria 4.0, como IoT, Big Data e Machine Learning, para melhorar eficiência e eficácia dos controles de qualidade. Os resultados indicam redução de erros, controle de qualidade mais preciso e otimização da tomada de decisões. O estudo fornece um legado acadêmico importante para profissionais e acadêmicos em administração, evidenciando a relevância da Qualidade 4.0 para o controle de qualidade produtivo na era digital.
Eclectic Teaching Method: A Paradigm Shift in Contemporary Pedagogy for an Inclusive Classroom
Authors: Fru-Ngongban Akenji Cliford
Published: July 2023

The constant search for teaching techniques and strategies that take into account the diversity of students in an inclusive classroom is one of the biggest difficulties facing instructors today. Before steps are taken to implement changes in the classroom, it is crucial to understand that learners' characteristics, particularly their social, economic, and cultural setting, since these aspects are  very important in any classroom situation. Given the importance of inclusiveness, the eclectic approach enables teachers to examine learners from various perspectives. This technique allows the teacher to explain the material to the learners using various techniques, employs a variety of teaching resources in order to respond to the various ways of learning inherent among learners. This paper therefore examines the issue of the eclectic method in an inclusive classroom. It highlights some recommendations to teachers in an inclusive classroom. This is followed by a conclusion.
Usos do território pelo turismo em Maceió-AL
Authors: Barros de Araújo Pedro , Teles de Carvalho Antônio Alfredo
Published: July 2023

Nos últimos anos, Maceió está entre os destinos brasileiros mais procurados por turistas domésticos e internacionais, o que implica na implantação denovas estruturas voltadas para sua fluidez e seu crescimento. A adequação do território para tal intencionalidade é, invariavelmente, sentida pela população que compartilha o território, porém com um propósito distinto: o seu uso como abrigo. Buscamos no presente trabalho identificar as marcas territoriais deixadas pelo turismo nareferida cidade a partir dos seusprincipais condicionantes, da sua expansão, bemcomo das relações entre a populaçãomaceioense e o turismo, e das diferentesformas de uso doterritório. Para tal intento, foi realizada uma revisão bibliográficae documental acerca da atividade turística em Maceió, mais especificamentequantoàs infraestruturas implantadas, a partir do conceito deterritório usado. Dessa forma,foi possível identificar uma gama de infraestruturas e os impactos delas decorrentes,no momento atual, e discutirpossíveis impactos futuros, emanados sobretudo da combinação entre a alta demanda e a escassez de espaços.
Capitalismo neoliberal
Authors: Lima dos Santos Júlia , Souza Angelita
Published: July 2023

Neste artigo, sintetizamos as contribuições de algumas autoras feministas – Nancy Fraser; Wendy Brown; Saskia Sassen – em seus exercícios de interpretação da fase neoliberal do capitalismo, análises que procuraram ir além da explicação no campo da economia. A busca de conhecimento por meio de estudos dessas autoras se justifica, pois são obras esclarecedoras, que alcançaram grande ressonância neste século. A metodologia envolve exclusivamente a pesquisa bibliográfica.
MEDIDAS DE CONTROLE FÍSICAS PARA REDUZIR A AMEAÇA DE PLANORBÍDEOS DA ESPÉCIE BIOMPHALARIA GLABRATA NO SISTEMA ABASTECIMENTO DE MARIANA, MG
Authors: Reis Isabel Francisco de Araújo , Santiago Aníbal da Fonseca , Pilz de Castro Ana Letícia , Leôncio Hamilton Cristiano
Published: July 2023

Contaminantes biológicos podem chegar aos mananciais de abastecimento por diferentes rotas. O Schistosoma mansoni é o agente etiológico da esquistossomose e em seu ciclo de vida, o parasita desenvolve-se no ser humano (hospedeiro definitivo) e em planorbídeos do gênero Biomphalaria (hospedeiro intermediário). Na cidade de Mariana, MG, Brasil foi identificada a espécie Biomphalaria glabrata no manancial de abastecimento Córrego do Seminário responsável por abastecer uma importante estação de tratamento de água da cidade. Como a introdução de moluscicidas não é uma medida de controle recomendável para sistemas de abastecimento por possuir efeitos nocivos à saúde humana, o presente estudo procurou alternativas para reduzir esse perigo biológico por meio de medidas de controle de custos acessíveis e eficazes. A abordagem utilizada na pesquisa foi quali-quantitativa e contou com pesquisa bibliográfica, documental, análises laboratoriais com a utilização de dados secundários e trabalho de campo. Os resultados obtidos indicaram que métodos de controle físico associados com ações de educação em saúde e procedimentos operacionais adequados foram eficientes no controle desses planorbídeos. Esse estudo de caso representou uma contribuição para os municípios brasileiros, pois atualmente existe um número considerável de cursos d´água onde foi identificada a presença desses planorbídeos. Conhecer estratégias para controlá-los a custos acessíveis pode assessorar gestores de sistemas de abastecimento na resolução do problema, caso a proliferação desses planorbídeos ocorra em seus sistemas de abastecimento.
CARACTERIZAÇÃO GRAVIMÉTRICA COMO ETAPA DE DIAGNÓSTICO DE RESÍDUOS SÓLIDOS: ESTUDO EM MUNICÍPIO DE PEQUENO PORTE
Authors: Cruz Rodrigues Gabriela , Salgado Vargas Isabela , Rodrigues Castro Samuel
Published: July 2023

A geração de resíduos sólidos urbanos (RSU) aumentou com o crescimento das cidades ao longo dos anos, sendo necessária uma destinação final ambientalmente adequada. O presente trabalho tem por objetivo analisar os RSU gerados em municípios de pequeno porte, tendo como estudo de caso uma cidade com aproximadamente 15.000 habitantes no Sul de Minas Gerais. Para tanto, foram levantadas as características qualiquantitativas dos resíduos sólidos domiciliares com base em três campanhas de caracterizações gravimétricas, com dados submetidos a testes estatísticos não-paramétricos de U-Mann Whitney e de Kruskal-Wallis em análises comparativas entre dados das campanhas. Os resultados obtidos não evidenciaram diferenças significativas entre as frações avaliadas das campanhas a 95% de confiança, o que possibilitou reportar um resultado gravimétrico único para os resíduos sólidos domiciliares do município. Obteve-se 50,1% compondo a fração de orgânicos, 19,5% a fração de recicláveis e 30,4% de rejeitos. Os resultados demonstram que 69,6% dos resíduos que estão sendo depositados no aterro do município possuem potencial de recuperação, o que representaria mensalmente cerca de 106,3t de orgânicos e 41,5t de recicláveis. Diante da representatividade majoritária de municípios classificados como de pequeno porte, observa-se que o cenário evidenciado e as discussões apresentadas no presente estudo sejam comuns a outros cenários do país, servindo de base para a gestão, tomada de decisão e melhoria do gerenciamento de resíduos.
AVALIAÇÃO DA EFICIÊNCIA DE REVESTIMENTO À BASE DE PEAD NA PROTEÇÃO DE ESTRUTURAS DE CONCRETO ARMADO DE UMA ESTAÇÃO DE TRATAMENTO DE ESGOTO SANITÁRIO
Authors: Mota Maykon Williann , Oliveira Paulo Laís de , Pereira de Lima Euclides Antônio
Published: July 2023

A degradação do concreto é um fenômeno comum que está condicionado ao meio que as estruturas estão inseridas e ao tempo de exposição, o que pode acelerar tal desgaste. Os efluentes domésticos são compostos de elementos que podem criar ambientes altamente agressivos que causam uma rápida degradação das estruturas de concreto. Características físico-químicas do esgoto doméstico como temperatura, DBO, DQO, ácidos voláteis e turbidez podem interferir na durabilidade das estruturas de concreto. Sendo assim, são necessários produtos e tecnologias que proporcionem a proteção do concreto em ambientes altamente agressivos. Este estudo objetivou testar um revestimento anticorrosivo à base de PEAD como alternativa de proteção das estruturas de concreto das caixas de passagem de uma Estação de Tratamento de Esgoto Sanitário. Para isso, foi realizado o levantamento das patologias existentes nas caixas de passagem na saída dos reatores anaeróbios, a caracterização físico-química do esgoto sanitário e a aplicação da Metodologia de Estimativa do Grau de danos (GDE-UnB) como forma de identificar e quantificar o dano causado pelo esgoto sanitário nas placas anticorrosivas. As patologias encontradas nas caixas de passagem foram a desagregação, eflorescências, fissuras, manchas e desplacamento. O esgoto sanitário possui características físico-químicas com similaridades aos estudos comparativos utilizados neste trabalho. O Grau do Dano estimado foi considerado pequeno, comprovando a eficiência das placas anticorrosivas na contenção das ações físicas, químicas e biológicas causadas pelo ambiente de uma Estação de Tratamento de Esgotos.
OPORTUNIDADES DE PRODUÇÃO MAIS LIMPA NO PROCESSO DE TRANSFORMAÇÃO DA MANDIOCA EM FARINHA: “CASA DE FARINHA”
Authors: SANTOS IAINA PRISCILA , ALENCAR ROSA
Published: July 2023

O cultivo e o consumo da mandioca e seus derivados fazem parte do cotidiano de milhões de brasileiros, desde a cultura de povos indígenas originários. Diante disso, é fundamental que a produção e comercialização da farinha de mandioca esteja de acordo com as Boas Práticas de Fabricação (BPF), a fim de garantir condições higiênico-sanitárias para trabalhadores e consumidores. Este trabalho teve como objetivo descrever os processos de transformação da mandioca em farinha tradicional e “beijusada”, observados em quatro unidades produtoras popularmente conhecidas como “casas de farinha”, no município de Cruz das Almas-BA. A metodologia utilizada para a coleta de dados atendeu critérios exploratórios, com revisão de literatura e visita de campo para acompanhamento das atividades produtivas realizadas pelos trabalhadores. Foram apresentados os principais insumos utilizados, os processos e os resíduos gerados ao longo da produção nas unidades visitadas, com ênfase na manipueira, um resíduo líquido altamente prejudicial ao meio ambiente. Como resultado foram feitas propostas de melhorias ambientais e sanitárias, baseadas nas premissas de Produção mais Limpa, conforme estabelecido pelo Centro Nacional de Tecnologias Limpas. Pretende-se, portanto, que a produção de farinha se converta em uma prática orientada pela preservação do meio ambiente, sem prejuízos históricos e culturais na produção tradicional.
Consensus molecular subtyping of colorectal carcinoma brain metastases reveals a metabolic signature associated with poor patient survival
Authors: Irmer Barnabas , Wlochowitz Darius , Krekeler Carolin , Richter Katharina Maria , Chandrabalan Suganja , Bayerlova Michaela , Wolff Alexander , Lenz Georg , Conradi Lena‐Christin , Schildhaus Hans‐Ulrich , Stadelmann Christine , Rohde Veit , Proescholdt Martin , Salinas Gabriela , Homayounfar Kia , Kuhlmann Tanja , Hailfinger Stephan , Pukrop Tobias , Menck Kerstin , Beissbarth Tim , Bleckmann Annalen
Published: January 2025

The transcriptomic classification of primary colorectal cancer (CRC) into distinct consensus molecular subtypes (CMSs) is a well‐described strategy for patient stratification. However, the molecular nature of CRC metastases remains poorly investigated. To this end, this study aimed to identify and compare organotropic CMS frequencies in CRC liver and brain metastases. Compared to reported CMS frequencies in primary CRC, liver metastases from CRC patients were CMS4‐enriched and CMS3‐depleted, whereas brain metastases mainly clustered as CMS3 and rarely as CMS4. Regarding overall survival rates, CMS4 was the most favorable subtype for patients with hepatic lesions, followed by CMS1 and CMS2. The survival of patients with brain metastases did not correlate with CMS. However, we identified a CMS3‐related metabolic gene signature, specifically upregulated in central nervous system (CNS)‐infiltrating CRC, as a negative prognostic marker and potential tumor progressor. In summary, subtyping of CRC metastases revealed an organotropic CMS distribution in liver and brain with impact on patient survival. CNS‐infiltrating CRC samples were enriched for CMS3 and predictive metabolic biomarkers, suggesting metabolic dysregulation of CRC cells as a prerequisite for metastatic colonization of the brain.
Trans‐Conductive Melt Pool Scaling and its Implications for Parameter Transfer in Laser Powder Bed Fusion for Metals with High Thermal Diffusivity
Authors: Döring Markus , Gehring Matthias , Schmidt Michael
Published: January 2025

For the development of alloys for laser powder bed fusion, it is desirable to enable a free choice of laser scan speed while avoiding porosity formation. This is due to the role of scan speed and melt pool size/shape in determining microstructure formation from solidification and associated mechanical properties. It is found that melt pool depth predicts the optimum in porosity formation, independent of the scan speed. To transfer this optimum melt pool depth to different scan speeds, the normalized enthalpy β and the normalized energy density (), an extension of the volume energy density, are examined for four binary aluminum–nickel alloys. Without modifications, these energy input parameters cannot be applied over a wide range of laser scan speeds for materials with high thermal diffusivity. The Peclet number is used to distinguish between high and low scan speeds relative to the material's thermal diffusivity. By calculating the absorptivity from melt pool width and examining the trans‐conductive (Peclet number around 1) melt pool scaling, it is found that the native formulations of β and need to be multiplied by the Peclet number to be applicable for low laser scan speeds.
Degradation Behavior and Mechanical Properties of Porous Biodegradable FeMnC Alloys Produced by Powder Metallurgy for Biomedical Applications
Authors: Cherqaoui Abdelhakim , Cao Quang Nguyen , Paternoster Carlo , Gélinas Simon , Mengucci Paolo , Blais Carl , Mantovani Diego
Published: January 2025

The advent of biodegradable implants represents a landmark orientation in the biomedical field toward a new generation of medical devices, offering improved patient outcomes, and eliminating the need for subsequent surgeries. FeMn alloys are well‐established as promising candidates for such applications. This study analyzes the microstructure, mechanical properties, and degradation behavior of FeMnC alloys produced via pressing and sintering process using water‐atomized FeMnC powder. To investigate the impact of pore size and volume fraction on the mechanical properties and degradation rates, two groups of FeMnC samples were prepared, one compacted at 600 MPa (CP 600) and the other at 700 MPa (CP 700). In addition, pure Fe samples compacted at 600 MPa and prepared using the same methodology were used as a reference. Chemical analysis carried out on both the pre‐alloyed powder and the resulting sintered samples (CP 600 and CP 700) revealed a significant reduction in the amount of Mn, O, and notably C after sintering. The pure Fe group showed the greatest mechanical strength with an average tensile rupture strength of 446 ± 24 MPa. Among the three groups, CP 600 exhibited the highest degradation rate (−0.339 ± 0.057 mmpy) after 14 days of static immersion degradation test in modified Hanks' solution, demonstrating a degradation behavior characterized by mass gain.
Deciphering and Enhancing Rate‐Determining Step of Sodium Deposition towards Ultralow‐Temperature Sodium Metal Batteries
Authors: Niu Yuxiang , Yang Jinlin , Meng Fanbin , Sun Zejun , Jiang Chonglai , Liu Yuan , Xu Hongfei , Wang Meng , Yang Haotian , Zhu Yupeng , Wu Gang , Chen Wei
Published: January 2025

Achieving high ionic conductivity and stable performance at low temperatures remains a significant challenge in sodium‐metal batteries (SMBs). In this study, we propose a novel electrolyte design strategy that elucidates the solvation structure‐function relationship within mixed solvent systems. A mixture of diglyme and 1,3‐dioxolane was developed to optimize the solvation structure towards superior low‐temperature electrolyte. Molecular dynamics simulations and Raman spectra results reveal the solvent‐separated ion pairs and contact ion pairs dominated solvation structure in the designed electrolyte, displaying a superior ionic conductivity of 1.78×10−3 S cm−1 at −40 °C. Besides, comprehensive kinetic analysis shows Na+ transportation in the electrolyte shows a greater impact on sodium plating than Na+ transport through the solid electrolyte interphase or charge transfer. As a result, the electrolyte enables stable operation for over 12,000 hours in Na
Na cells at −40 °C. In Na
Na2/3Ni1/4Cu1/12Mn2/3O2 full cells, it maintains a high capacity retention of 92.4 % over 600 cycles with an initial specific capacity of 89.4 mAh g−1 at −40 °C, and achieves 81.7 % capacity retention after 50 cycles with an initial specific capacity of 75.3 mAh g−1 at −78 °C. These results pave the way for the development of high‐performance SMBs capable of operating under ultralow temperatures.
Manipulating Charge Distribution at Organic‐inorganic Interface via Optimizing Substituents for Sustainable Water Electrolysis
Authors: Jiang Ling , Hao Yixin , Gu Mingzheng , Deng Liming , Chen Qiao , Zhang Xiaojun , Li Linlin , Peng Shengjie , Wang Guangfeng
Published: January 2025

The space charge effect induced by high‐quality heterojunctions is essential for efficient electrocatalytic processes. Herein, we delicately manipulate intermolecular charge transfer by modifying substituents (−g=‐CH3, ‐H, ‐NO2) with various electron donating/withdrawing capabilities in CoPc‐g/CoS organic–inorganic heterostructures. CoPc‐CH3, as a typical electron donor, transfers more electrons to CoS due to the presence of ‐CH3, forming the strongest space electric field and thus regulating the dual active sites at the interface. Furthermore, oxygen‐containing intermediates preferentially adsorb on the positively charged CoPc‐CH3 side, and the rapid accumulation of electrons on the CoS side decelerates catalyst dissolution at the oxygen evolution reaction (OER) potential, ensuring the stable OER process under the optimized adsorbate evolution mechanism. As a result, CoPc‐CH3/CoS catalyst exhibits the lowest overpotential and remains stable for 150 h at 0.5 A cm−2 in the membrane electrode assembly electrolyzer. The method provides a novel strategy for accurately regulating the space electric field of heterojunctions.
Effect of Processing Conditions on Process‐Induced Degradation of Poly(Lactic Acid) During Single‐Screw Extrusion
Authors: Velghe Ineke , Buffel Bart , Vandeginste Veerle , Thielemans Wim , Desplentere Frederik
Published: January 2025

The aim of this study is to investigate the effect of processing conditions on the degradation of poly(lactic acid) (PLA) during single‐screw extrusion. A 25 full factorial design of experiments was used to systematically screen significant main and interaction effects caused by five processing conditions: the moisture content in the granules (dried–undried), processing temperature (190°C–230°C), length of the compression zone of the screw (6D–11D), diameter of the capillary die (2–4 mm), and screw rotation speed (20–40 rpm). The effect of 32 extrusion combinations on the molecular weight of PLA (102,850 Da) was statistically analyzed. The molecular weight after processing varied between 100,750 and 66,500 Da and was determined by four main effects and three interaction effects. A high moisture content had the largest effect (−17,846 Da), followed by a high processing temperature of 230°C (−7260 Da), a small die diameter of 2 mm (−1849 Da) and a low screw rotation speed of 20 rpm (−4730 Da). Aside from main effects, the importance of studying interaction effects was emphasized, since the moisture content influenced degradation caused by temperature (−4019 Da), screw speed (4621 Da), and die geometry (1993 Da).
Synergistic Effects of Surface‐Modified Glass Fiber on Polylactic Acid Matrix Composites Reinforcement and Toughening
Authors: Tan Qing , Mao Chen , Hao Xiaochang , Tao Ye , Gong Xinghou
Published: January 2025

To address the challenges of high brittleness and poor crystallization capability in polylactic acid (PLA), glass fiber (GF), and polycaprolactone (PCL) were selected as reinforcing and toughening agents, respectively, for property modification. In the resulting composites, an interfacial layer forms between the polymer matrix and GF, significantly influencing the interfacial adhesion quality and the overall mechanical properties of the material. To enhance interfacial compatibility, oleic acid (OA) was introduced as a coating via the hydrophilic SiOSi bonds on the GF surface. Combined with treatment using a silane coupling agent (KH550), this process resulted in dual‐surface modification of glass fiber (OKGF). PLA/PCL/GF (or OKGF) composites with mass fractions of 5%, 10%, 15%, and 20% OKGF were fabricated using solution dissolution and melt blending techniques. Scanning electron microscopy analysis revealed excellent interfacial adhesion between OKGF and the polymer matrix. The composite with 15% OKGF content exhibited optimal mechanical properties, achieving maximum tensile strength (65.5 MPa) and modulus (1113.0 MPa), representing a significant enhancement. Moreover, OKGF served as an effective heterogeneous nucleating agent, resulting in a crystallinity of 19.1% at 15% OKGF content—an 88% increase compared with the PLA/PCL blend (10.2%).
VMD‐FBCCA classification method for SSVEP brain–computer interfaces
Authors: Tan Ping , Wang Fengsheng , Zhou Kaijun , Shen Yi
Published: January 2025

A steady‐state visually evoked potential (SSVEP) is a brain response to specific frequencies of visual stimuli, including their harmonic frequencies. However, this signal is susceptible to interference from spontaneous and rhythms in electroencephalography (EEG) signals because they overlap from 8 to 40 Hz. This can reduce the recognition accuracy of SSVEP brain–computer interfaces (BCIs). To address this problem, a variational mode decomposition–based filter bank canonical correlation analysis (VMD‐FBCCA) algorithm is proposed, which integrates the adaptive characteristics of VMD and the training‐free nature of the FBCCA algorithm. First, the EEG signal of each channel is transformed into intrinsic mode functions (IMFs) by the VMD algorithm, which extracts frequency components of the SSVEP from each IMF. Next, a particle swarm algorithm is employed to optimize the weights of the IMFs and reconstruct the EEG signals. This reconstruction selectively enhances the IMFs in the target SSVEP frequency band while suppressing interference from other bands. Finally, the reconstructed EEG is classified using FBCCA to decode the SSVEP‐BCI signal. To evaluate its effectiveness, the proposed algorithm is tested on datasets from the BCI Competition. The results demonstrate that VMD‐FBCCA outperforms FBCCA, showing improvements in both the average recognition accuracy and information transmission rate (8.91 bits/min). Moreover, the best recognition accuracy achieved for individual subjects is enhanced by .
Macrophage Infiltration and ITGB2 Expression in ESCC: A Novel Correlation
Authors: Huang Tao , Wei Longqian , Zhou Huafu , Liu Jun
Published: January 2025

Background

Esophageal squamous cell carcinoma (ESCC) is one of the most prevalent and lethal malignancies worldwide. Despite progress in immunotherapy for cancer treatment, its application and efficacy in ESCC remain limited. Therefore, there is an ongoing need to explore potential molecules and therapeutic strategies related to tumor immunity in ESCC.

Methods

In this study, we integrated high‐throughput sequencing data, gene chip data, single‐cell sequencing data, and various bioinformatics analysis methods along with experimental approaches to identify key genes involved in immune infiltration in ESCC and investigate their relationship with immune cell development, as well as the potential of these key genes in immunotherapy.

Results

We discovered and validated a positive correlation between macrophage infiltration and ITGB2 expression in ESCC. ITGB2 is overexpressed in ESCC and has potential as a prognostic biomarker for the disease. We present for the first time the finding that the expression of ITGB2 in infiltrating macrophages increases as these macrophages polarize toward a tumor‐promoting phenotype in ESCC. Moreover, during the progression of ESCC, ITGB2 expression in infiltrating macrophages is upregulated. The higher the expression of ITGB2, the more feasible it is to target macrophages. Additionally, we found that evaluating immune therapy responses in ESCC patients through ITGB2 expression is a viable approach. Furthermore, we identified three miRNAs associated with abnormal ITGB2 expression, providing insights into the upstream molecular interactions of ITGB2.

Conclusions

Macrophage infiltration in ESCC is closely associated with ITGB2, which holds significant potential for immunotherapy applications in ESCC. Based on our findings and prior studies, we propose a novel hypothesis: inducing M1 macrophages in vitro, knocking out ITGB2, and then reinfusing these ITGB2‐knockout M1 macrophages into ESCC patients may represent a promising new immunotherapy strategy, providing a new avenue for ESCC immunotherapy.
High‐Performance Pd Cluster Catalyst Modified with N‐Doped Carbon for Multicomponent VOCs Oxidation
Authors: Zhang Zexu , Tao Jinxiong , Hao Zhixing , Zhou Xin , Hou Zhiquan , Deng Jiguang , Dai Hongxing , Liu Yuxi
Published: January 2025

The paint production sector emits both aromatic compounds and oxygenated volatile organic compounds (OVOCs). Supported palladium catalysts have demonstrated effective oxidation performance for each type of VOCs separately; however, the challenge persists in managing the competitive adsorption of different VOCs types on Pd‐based catalysts. In this study, we developed a nitrogen‐doped carbon (NC)‐modified TiO2‐supported catalyst featuring a highly dispersed, cluster‐type Pd structure created through in situ pyrolysis method, which offers more catalytic active sites than conventional nanoparticle catalysts. The catalyst's key characteristics, including high noble‐metal usage and an ideal Pd0/Pd2+ ratio, enhance its catalytic performance for multicomponent VOCs oxidation, reaching T90% values of 167 and 191 °C (at a space velocity of 40,000 mL/(g h)). Furthermore, the NC structure created through in situ pyrolysis technique aids in diminishing the inhibitive adsorption effect of ethyl acetate on o‐xylene and improves the catalyst's resistance to water. This research presents a promising approach for the rational design of highly dispersed Pd catalysts that have enhanced water resistance and offers new understanding in managing competitive adsorption for the efficient removal of multicomponent aromatic VOCs and OVOCs in complicated settings.
Polyethylene Functionalized with Imidazolium and Pyridinium Moieties through Radiation‐Induced Grafting for Alkaline Solid Polymer Electrolyte Membranes
Authors: Govind Bharath , Rattan Sunita , Singhal Prachi , Ameduri Bruno , Tyagi Ankit , Modak Arindam
Published: January 2025

Hydrocarbon‐based polymer electrolytes hold great promise for practical electrochemical device deployment but suffer from limitations such as ionic conductivity, alkaline stability, and hydrophobicity. This work reports a new membrane, LLDPE‐g‐1VIm/4VP, prepared by radiation grafting a binary mixture of 1‐vinyl imidazole and 4‐vinylpyridine onto linear low‐density polyethylene. Short branches in LLDPE are hypothesized to regulate water uptake, thus improving dimensional stability. Under optimized conditions, the membrane exhibits a relatively high ionic conductivity of 39.86 mS cm−1 at 70 °C, good mechanical strength, improved dimensional stability, and moderate alkaline stability even after 240 h at 60 °C under harsh conditions. Preliminary evaluations demonstrate their potential as solid polymer electrolytes for electrochemical energy applications, including alkaline anion exchange membrane fuel cells.
Colorimetric analysis of intraoral scans: A novel approach for detecting gingival inflammation
Authors: Hassan Mohamed Ahmed , Silva do Amaral Guilherme Castro Lima , Saraiva Luciana , Holzhausen Marinella , Mendes Fausto Medeiros , Pannuti Claudio Mendes , Stewart Bernal , Malheiros Zilson M. , Benítez Carlos , Nakao Laís Yumi Souza , Villar Cristina Cunha , Romito Giuseppe Alexandre
Published: January 2025

Background

Gingivitis, a widely prevalent oral health condition, affects up to 80% of the population. Traditional assessment methods for gingivitis rely heavily on subjective clinical evaluation. This study seeks to explore the efficacy of interpreting the color metrics from intraoral scans to objectively differentiate between healthy and inflamed gingiva.

Methods

This study used the percentage of bleeding on probing (BOP%) as the clinical reference standard. Intraoral scans, obtained before and after gingivitis treatment using a scanner, were analyzed through a custom MATLAB script to quantify HSV (hue, saturation, value) and CIELAB (Commission Internationale de l'Eclairage L*a*b*) color coordinates. The region of interest was a 2‐mm‐wide gingival strip along the buccal margin of the maxillary anterior teeth. Linear regression analysis was performed to evaluate the relationship between photometric outcomes and continuous, dichotomous, and categorical BOP data. Diagnostic accuracy was assessed using the area under the receiver operating characteristic (ROC) curve (AUC), as well as sensitivity and specificity measures.

Results

The analysis included clinical and digital color data from 110 scans, adhering to the STROBE (Strengthening the Reporting of Observational Studies in Epidemiology) guidelines. The multilevel linear regression analysis underscored a significant correlation between the BOP% and digital color metrics, specifically the CIELAB a* (red‐green chroma), CIELAB b* (yellow‐blue chroma), and color saturation, with AUC performances of 70%, 79.5%, and 80.8%, respectively.

Conclusion

Digital color analysis of intraoral scans has demonstrated a range of performance from acceptable to excellent in distinguishing sites with BOP. This innovative approach presents a promising tool for dentists and researchers in the accurate diagnosis, screening, and management of gingivitis.

Plain Language Summary

Our study focuses on finding a better way to detect gingivitis, a common gum disease affecting many people. Traditional methods rely on the dentist's visual inspection, which can be subjective. We explored the use of color measurements from digital intraoral scans to objectively identify healthy versus inflamed gums. We analyzed 110 scans from 55 participants, examining the color differences in the gums before and after treatment. By measuring specific color values, we achieved up to 80.8% accuracy in distinguishing between healthy and inflamed gums. This method could offer a more reliable tool for dentists and researchers to diagnose and manage gingivitis, leading to better oral health outcomes.
Simultaneous multislice diffusion imaging using navigator‐free multishot spiral acquisitions
Authors: Jiang Yuancheng , Li Guangqi , Shao Xin , Guo Hua
Published: January 2025

Purpose

This work aims to raise a novel design for navigator‐free multiband (MB) multishot uniform‐density spiral (UDS) acquisition and reconstruction, and to demonstrate its utility for high‐efficiency, high‐resolution diffusion imaging.

Theory and Methods

Our design focuses on the acquisition and reconstruction of navigator‐free MB multishot UDS diffusion imaging. For acquisition, radiofrequency‐pulse encoding was used to achieve controlled aliasing in parallel imaging in MB imaging. For reconstruction, a new algorithm named slice–projection onto convex sets–enhanced inherent correction of phase errors (slice‐POCS‐ICE) was proposed to simultaneously estimate diffusion‐weighted images and intershot phase variations for each slice. The efficacy of the proposed methods was evaluated in both numerical simulation and in vivo experiments.

Results

In both numerical simulation and in vivo experiments, slice‐POCS‐ICE estimated phase variations more precisely and provided results with better image quality than other methods. The intershot phase variations and MB slice aliasing artifacts were simultaneously resolved using the proposed slice‐POCS‐ICE algorithm.

Conclusion

The proposed navigator‐free MB multishot UDS acquisition and reconstruction method is an effective solution for high‐efficiency, high‐resolution diffusion imaging.
Factor Structure and Measurement Invariances of the PHQ‐9 in Chinese Students Across Gender and Age
Authors: Cao Yanjing , Xu Chenchen , Lu Shan , Li Qi , Xiao Jing
Published: January 2025

The patient health questionnaire‐9 (PHQ‐9) is widely utilized in assessing individuals' depression levels. Nevertheless, research regarding its factor structure and measurement invariance remains inadequate. The aim of this study was to delve into the factor structure of the PHQ‐9 and to further investigate its measurement invariance across gender and age as a prerequisite for its use in cross‐group comparisons. A confirmatory factor analysis (CFA) was conducted on 7422 Chinese students to assess the best‐fitting factor structure of the PHQ‐9. Furthermore, a serial CFA was undertaken to investigate measurement invariance across genders and age groups. CFA confirmed the two‐factor model with the three items “sleep disturbance,” “fatigue,” and “appetite change” loading on somatic factor, and the other items loading on cognitive/affective factor as the best‐fit structure. Findings demonstrated that the PHQ‐9 had measurement invariance across gender and age. CFA and measurement invariance results support the application of the PHQ‐9 for assessing an individual's depression.
Natural products and long non-coding RNAs in prostate cancer: insights into etiology and treatment resistance
Authors: Elimam Hanan , Zaki Mohamed Bakr , Abd-Elmawla Mai A. , Darwish Hebatallah A. , Hatawsh Abdulrahman , Aborehab Nora M. , Mageed Sherif S. Abdel , Moussa Rewan , Mohammed Osama A. , Abdel-Reheim Mustafa Ahmed , Doghish Ahmed S.
Published: January 2025

Globally, the incidence and death rates associated with cancer persist in rising, despite considerable advancements in cancer therapy. Although some malignancies are manageable by a mix of chemotherapy, surgery, radiation, and targeted therapy, most malignant tumors either exhibit poor responsiveness to early identification or endure post-treatment survival. The prognosis for prostate cancer (PCa) is unfavorable since it is a perilous and lethal malignancy. The capacity of phytochemical and nutraceutical chemicals to repress oncogenic lncRNAs and activate tumor suppressor lncRNAs has garnered significant attention as a possible strategy to diminish the development, proliferation, metastasis, and invasion of cancer cells. A potential technique to treat cancer and enhance the sensitivity of cancer cells to existing conventional therapies is the use of phytochemicals with anticancer characteristics. Functional studies indicate that lncRNAs modulate drug resistance, stemness, invasion, metastasis, angiogenesis, and proliferation via interactions with tumor suppressors and oncoproteins. Among them, numerous lncRNAs, such as HOTAIR, PlncRNA1, GAS5, MEG3, LincRNA-21, and POTEF-AS1, support the development of PCa through many molecular mechanisms, including modulation of tumor suppressors and regulation of various signal pathways like PI3K/Akt, Bax/Caspase 3, P53, MAPK cascade, and TGF-β1. Other lncRNAs, in particular, MALAT-1, CCAT2, DANCR, LncRNA-ATB, PlncRNA1, LincRNA-21, POTEF-AS1, ZEB1-AS1, SChLAP1, and H19, are key players in regulating the aforementioned processes. Natural substances have shown promising anticancer benefits against PCa by altering essential signaling pathways. The overexpression of some lncRNAs is associated with advanced TNM stage, metastasis, chemoresistance, and reduced survival. LncRNAs possess crucial clinical and transitional implications in PCa, as diagnostic and prognostic biomarkers, as well as medicinal targets. To impede the progression of PCa, it is beneficial to target aberrant long non-coding RNAs using antisense oligonucleotides or small interfering RNAs (siRNAs). This prevents them from transmitting harmful messages. In summary, several precision medicine approaches may be used to rectify dysfunctional lncRNA regulatory circuits, so improving early PCa detection and eventually facilitating the conquest of this lethal disease. Due to their presence in biological fluids and tissues, they may serve as novel biomarkers. Enhancing PCa treatments mitigates resistance to chemotherapy and radiation.
Robust pig extraction using ground base depth images for automatic weight estimation
Authors: Win Khin Dagon , Kawasue Kikuhito , Tokunaga Tadaaki
Published: January 2025

Dark colored pigs (Berkshire, Duroc, etc.) are widely recognized nationwide in Japan for their exceptional taste, with the southern Kyushu region being a renowned production area for these esteemed breeds. However, estimating the weight of these pigs using a camera presents a unique challenge. The key process in a camera-based weight estimation system is the precise extraction of the target pig from the background. Typically, cameras capture images from above, as the top-view images provide the most specific growth indicators. However, the image from above contains a ground image. Since Berkshire and Duroc pigs are black and red, respectively, they blend into the ground, making it difficult to accurately segment the pigs in the images. Thus, it is crucial to perfectly distinguish between the ground and the pigs. Therefore, a new extraction method is proposed to distinguish between the ground and pigs by converting depth data based on the pig's position. To enhance the efficiency of pig farming and alleviate the burden on workers, our goal is to develop a system that automatically measures the weight of Berkshire pigs for shipment without background interference. In this study, we installed the system at a Berkshire pig farm and demonstrated the effectiveness of this innovative extraction method for camera-based weight estimation.