bluuebunny/crossref_metadata_2025 huggingface dataset:
A miniature of High (Upper) Armenian (11-14 centuries)
Authors: Korkhmazian Emma
Published: November 2022

Գիրքը նվիրված է հայ մշակույթի զարգացման գործում հսկայական դեր ունեցած պատմական Հայաստանի Բարձր Հայք նահանգի գրքարվեստի ԺԱ.-ԺԴ. դդ. հուշարձանների ուսումնասիրությանը: Հեղինակը բացահայտել է Բարձր Հայքի գրչության և մանրանկարչության դպրոցի ակունքները, ձեռագիր մատյանների ձևավորման և հարդարման օրինաչափությունները, այս դպրոցի կապերն ու փոխազդեցությունները հայ գրքարվեստի այլ կենտրոնների` Գլաձորի, Տաթևի համալսարանների, Կիլիկիայի, Ղրիմի դպրոցների և բյուզանդական Պալեոլոգյան արվեստի հետ: Գիրքը հասցեագրված է միջնադարյան հայ արվեստի հարցերով զբաղվող մասնագետներին, հայագետներին, պատմաբաններին, բյուզանդագետներին, ինչպես նաև Հայաստանի արվեստի պատմությամբ հետաքրքրվող ընթերցասեր հասարակությանը:
Combating Domestic Violence Against Women: Does Italian Legislation Comply with the Istanbul Convention?
Authors: Braschi Sofia
Published: November 2022

Italian criminal law regarding domestic violence has undergone only limited amendments in order to fulfil the obligations enshrined in the Istanbul Convention. This article examines the scope of the offences included in the Criminal Code, in order to establish whether Italian legislation complies with the obligations of criminalisation established by articles 33 ff. of the Convention. To this end, the paper begins with some observations about the concept of domestic violence as accepted at national and international level; it then turns to analyse the crimes against physical and psychological violence, focusing on the offences of domestic ill-treatment and stalking. The article then examines aggravating circumstances and comes to the conclusion that reform is needed in order to update and rationalise the criminal law regarding domestic violence.
Management Practice Supporting Sustained Development in the German Art Collection
Authors: Krämer-Weidenhaupt Louisa
Published: November 2022

This study focuses on understanding how approaches to management can support sustained development in German art museums.

It thereby not only explores discussions surrounding management practice and sustainability, but also examines the conceptual ambivalence and tensions that arise at the intersection of the arts and theories of value within the German art museum context. By taking into account the amalgamation of political, historical and cultural undercurrents that inform management, policy decisions and practice, this study is able to gain an understanding of the systemic interactions which affect the potential for sustainable development as well as of limiting factors that shape management practice, such as the discursive formations which shape the ways in which professionals operate.
Smooth Structures on Spin Manifolds in Four Dimensions
Authors: Davis Simon
Published: November 2022

The estimate of the coefficient of the magnitude of the signature, which are defined by the number of positive and negative eigenvalues in the inequality representing smooth, oriented, simply connected, compact, spin four-manifolds with indefinite intersection forms can be increased until it is equal to the conjectured value. Therefore, if the intersection form is mE8⊕n0110, the oriented, simply connected, compact, spin four-manifold will admit a smooth structure if and only if n≥32m. The inequality is changed to n≥32m−1−12i, there is a 2i-fold spin covering of a non-spin manifold M given the demonstration of n≥32m for oriented, compact, spin manifolds. A closer examination of the proof reveals that the lower bound for b+ can be increased to 3|k| + 1, where k=315σ for a spin manifold, yielding b2≥118σ+2. The projection of a spin covering to a non-spin manifold yields the lower bound b2≥118σ, which establishes the prediction for the coefficients of intersection forms for this class of smooth, oriented, simply connected, compact four-manifolds.
Web Sites Need Much More User-Driven Interactivity
Authors:   Graz University of Technology, Austria, Zaka Bilal , Maurer Hermann ,   Graz University of Technology, Austria
Published: November 2022

Websites present information or services but often do not allow users to provide feedback or ask questions. The topic of this paper is to first discuss various types of interactivities that are currently available, and then explain what one would expect from advanced systems. The article makes it clear that much has still to be developed. We start by mentioning a number of currently used approaches and show that they almost exclusively belong to a category we call “provider-driven”. They miss the very desirable possibility of what we call “user-driven” feedback that is, at the most, available in a very rudimentary form. We then present some user-driven feedback attempts that culminate with a description of some of the features of a new system NID (for Net-Interactive Documents). We analyze and describe the first results obtained and, finally, summarize to show what future systems should provide.
The Incorporation of NID into Digital Libraries and Its Benefits
Authors:   Graz University of Technology, Austria, Eisenberger Sonja
Published: November 2022

This paper addresses the topic of the ongoing digitization of previously analogue knowledge collections, primarily libraries, i.e. mainly but not exclusively written materials in text format and additionally materials in images, video, and audio formats. A short introduction to digital books explains the extended ways of using them in contrast to their analogue predecessors and their incorporation into various systems such as NID (Net Interactive Documents). In one section, the topic of digital libraries is reviewed. A few of the most important representatives are briefly introduced. The 3.2 chapter applies to the software, which can be used for digital libraries. In the main part, an introduction is given to NID (Net Interactive Documents) and its current applications as well as projects planned for the future. Finally, different features of NID are compared with a similar system - Hypothes.is, and the advantages and disadvantages are explained.
Pemberdayaan Masyarakat Dalam Pemanfaatan Material Lokal Guna Pengembangan Ekowisata Berbasis Local Wisdom Desa Sidem
Authors: Saputri Diyah Ayu , Junianto Mochamad Rizqy
Published: November 2022

Local wisdom is the capital of the formation of noble characters who live in society, grow and develop continuously in public awareness. Local wisdom can be in the form of local knowledge, local skills, local intelligence, local resources, local social processes, local norms and ethics and local customs. Likewise in the field of architecture, local wisdom is an architectural design that adapts to the local climate, using local techniques and materials that are influenced by social, cultural and economic aspects of the local community. In this case, the selected location where the concept of local wisdom will be implemented is in Sidem Village, Gondang District. The purpose of this community service is to empower the community in the use of local materials for the development of Ecotourism based on Local Wisdom in Sidem Village, Gondang Tulungagung District. The implementation techniques used to implement these local local materials are as follows: 1) Preparation Phase. This stage includes team preparation, site survey, interviews with local communities, identification of problems and potentials, analysis of problems and potentials. 2) Implementation Phase. This stage includes the preparation of the draft design, implementation. 3) Evaluation and Reporting Stage. This stage includes evaluation of activities, preparation of activity reports. The result of this service is the implementation of community empowerment socialization by bringing up design concepts, because the community plays an important role in the development of ecotourism in Sidem Village.

Keywords - ecotourism, local materials, local wisdom, stakeholders, Tulungagung
Optimalisasi Pemanfaatan Pekarangan Rumah Sebagai Peluang Bisnis Keluarga
Authors: Kusumastuti Anggit Dyah
Published: November 2022

Utilization of the yard is the first step to stimulate the growth of the spirit of self hap and community participation. Mina Surya is one of a group of young entrepreneurs whohave the entrepreneurial spirit to change their mindset by optimizing the local potential around them through the use of home yards that can be developed into valueable commodities. The form of utilization carried out by Mina Surya is a private pool tourism object and aquaculture business as a family run business opportunity. Mina Surya is a young entrepreneur from Jeblog, Karanganom, Klaten who has a set of konwledge and skills (life skills) in the field of fisheries so as to develop local potential by optimizing the use of home yard land to become a private poll tourism object and aquaculture as a family business opportuniy.
Penerapan Teknologi Greenhouse pada Petani Sirih Hitam di Wonosobo
Authors: Harjunowibowo Dewanto , Fitria Haryani Fairusy , Rinanto Yudi
Published: November 2022

Piper Betle var. Nigra merupakan tanaman endemik family Piperaceae di Indonesia. Tanaman ini memiliki kandungan senyawa untuk antimikroba. Kebutuhan daun sirih hitam sebagai bahan baku obat menjadi potensi yang ingin dimanfaatkan oleh para petani di Wonosobo. Namun demikian, pembudidayaan sirih hitam ini lebih sulit karena hanya ada di hutan. Oleh karenanya, kegiatan ini ditujukan untuk mengenalkan teknologi greenhouse dan sistem kontrol microclimate kepada para petani agar mendapatkan hasil panenan yang berkualitas. Melalui pelatihan stek dan teknologi greenhouse, petani mitra mampu melakukan stek dengan benar dengan tingkat keberhasilan yang tinggi.
clima organizacional en las bibliotecas judiciales de la Provincia de Buenos Aires.
Authors: Williams José María , Silber Leonardo
Published: November 2022

Con el objetivo de estudiar cómo la cultura y el clima organizacional influyen en las condiciones laborales de las bibliotecas judiciales de la Provincia de Buenos Aires, se realiza un estudio exploratorio. Los datos se obtienen a partir de una encuesta a sus bibliotecarios con el fin de relevar aspectos subjetivos de su trabajo cotidiano en base a una serie de variables. Los resultados obtenidos permiten conocer de qué manera la cultura organizacional condiciona al desempeño laboral de profesionales.
La situación de la bibliotecología argentina en la aplicación de los Objetivos de Desarrollo Sostenible (ODS) de la Agenda 2030.
Authors: Monfasani Rosa
Published: November 2022

El desarrollo sostenible que requiere la Agenda 2030, adoptada por la Organización de las Naciones Unidas (ONU) en el año 2015, fue aprobada por los 193 Estados miembros que reconocieron que el mayor desafío del mundo actual es la erradicación de la pobreza y que este objetivo se debe lograr para hacer posible ese desarrollo. Las bibliotecas y otras organizaciones e instituciones bibliotecarias no están ajenas a este proceso y cumplen un rol fundamental. En la ejecución de este artículo, se hace una presentación general sobre el tema, se dan algunos ejemplos, se presenta la investigación realizada sobre la situación de Argentina a nivel país y en el concierto mundial y se dan algunos ejemplos y pautas que podrían ser útiles para el cumplimiento de los ODS.
Trama socio-histórica de la fundación de la Biblioteca de la Casa Natal de Sarmiento en San Juan (Argentina), en 1910.
Authors: Castro Elina Vanesa
Published: November 2022

El siguiente trabajo propone una reconstrucción de la historia de la Biblioteca de la Casa Natal de Sarmiento en el contexto de su fundación en 1910. Si bien la institución en sí misma es un organismo dual y es mayormente reconocida por su aspecto de Museo Nacional, contiene otra fisonomía poco estudiada. A partir de ello, el objetivo de este estudio pretende reconstruir su historia en sus orígenes a inicios del siglo XX. Dentro del tópico de referencia, el contexto social más las fuentes de análisis fueron interpretadas bajo el auxilio de la microhistoria (método inductivo) y la concepción de las mentalidades. De esta manera, se identifica una aproximación al campo burocrático que se complementa con el corpus conceptual de la historia del libro, la edición y la lectura en Argentina. Como corolario se obtuvo un análisis socio-histórico que puso en relieve el imaginario social de la figura de Domingo F. Sarmiento y lo que se entendía por este tipo de bibliotecas. Finalmente, el presente artículo exhibe parte de los resultados de una tesina de grado de licenciatura y constituye el primer avance dedicado íntegramente al tema.
ushnus Incas. Análisis de la literatura publicada
Authors: Urbizagástegui-Alvarado Rubén
Published: November 2022

Se estudia la literatura publicada sobre los ushnus incaicos desde 1966 hasta diciembre de 2020. Se identificaron 210 documentos producidos por 147 autores diferentes. El tipo de documento preferido para comunicar los resultados de las investigaciones son los artículos de revistas, seguidos de las ponencias en congresos nacionales e internacionales y los capítulos de libros. Para comunicar estos tres tipos de documentos se usaron los idiomas español e inglés preferentemente. 14 son los autores más productivos que representan el 9.5% de la población estudiada y son responsables del 55.8% de los documentos publicados sobre este asunto. La mayoría de estos documentos fueron producidos por investigadores peruanos ligados a organismos educativos públicos. Otra parte son investigadores americanos ligados también a universidades americanas. Se encontró una red de coautorías compuesta de 101 autores ligados por 163 lazos. Su densidad es igual a 0.032 indicando que es una red de baja densidad y tiene 25 subgrupos de distintas coautorías. La red de copalabras está compuesta de 152 palabras clave ligados por 327 lazos. Su densidad es igual a 0.029 indicando que es una red de baja densidad y tiene 14 subgrupos donde el mayor subgrupo es un componente gigante de 100 miembros palabras claves.
Espejando realidades. Las Redes Sociales en la co-construcción de una Museografía Digital.
Authors: Paz Rocío
Published: November 2022

A través del presente ensayo se pretende analizar la usabilidad de perfiles de museos en las Redes Sociales, para la construcción de la experiencia museal: que se inicia a través del espacio virtual y que podría consolidarse con la visita presencial. Se busca dejar asentada la relevancia del visitante, siendo su mirada la que completa la estructura museográfica propuesta.

Para efectivizar esta concepción de acción dual (museo -visitante) se crea una cercanía virtual a través de la construcción de perfiles de usuario institucionales. En este escrito, se pondrá en eje el uso de Instagram, como una de las redes con gran volumen de participación por parte de los museos y con una comunidad de usuarios consolidada.

La sala de los museos es el espacio de concreción material del relato expositivo. Entonces ¿qué ocurre cuándo la sala está cerrada o cuando el visitante se encuentra en un punto témporo - espacial distante? ¿Cómo podría propiciarse la democratización del acceso a la cultura? ¿Qué rol cumplen las Redes Sociales en la visibilización de los objetos museales?

No es posible pensar en los museos desde una perspectiva integral, sin considerar a su público: que son -podría decirse- su razón de ser. Es condición sine qua non de su funcionamiento, la posibilidad de establecer un encuentro dialógico entre el visitante y las exposiciones. Co-construir el museo implica deconstruir el espacio-tiempo y dar lugar a que el visitante aporte sus propios saberes, como piedra fundante, valiéndose de las herramientas que los avances tecnológicos proveen.
Spurious Satanists and Christian Cults
Authors: Scharnick-Udemans Lee-Shae Salma ,   Academic Publishing
Published: November 2022

This article explores the historical and contemporary entanglements of race, religion and media as it plays out through a four-part documentary series about deviant, dangerous and criminal Christian group Electus Per Deus, who were responsible for a spate of murders known collectively as the Krugersdorp Killings. Headed by a self-proclaimed powerful ex-Satanist witch, who was actively involved in on-going spiritual warfare, the group’s primary religious activity was to help educate about and assist with escape from the ‘Occult’ in general and Satanism in particular. A curious element of Electus Per Deus’ modus operandi was that the group’s members often masqueraded as Satanists, in order to advance their cause and secure the legitimacy of their claims. The community in which they were positioned vehemently rejected the Christian status of the group despite members claims to the contrary. This article argues that within the historical and contemporary political economies of race, religion and media, White Afrikaans Christian communities, such as those featured in Devilsdorp were inordinately favoured through the policies and practices of the apartheid regime and more recently the Afrikaner capture of commercial media. This re­ligious and racial privilege is reproduced by the series and serves as a reminder of the importance of intersectional, contextually informed approaches to the study of religious diversity, deviance, and danger.
Fatores associados aos determinantes para a confirmação da notificação pela COVID-19
Authors: Carvalho Mariane Cardoso , Fernandes Flávia Emília Cavalcante Valença , Alves de Melo Rosana
Published: November 2022

Objetivo: analisar os fatores associados aos determinantes para a confirmação dos casos notificados pela Corona virus Disease-2019 (COVID-19). Método: estudo transversal com a utilização dos dados de acompanhamento das notificações no estado de Pernambuco, entre fevereiro e agosto de 2020. Realizou-se estatística descritiva e regressão logística binária com razões de chance como medida de associação. Resultados: foram notificados 38.178 casos, sendo 59,9% confirmados. Fatores associados aos determinantes da confirmação: homens (OR:1,08; IC95%=1,02-1,14), idosos (OR 1,15; IC95%=1,09-1,22) e raça/cor branca (OR:1,10; IC95%=1,03-1,17). Alteração de olfato/paladar isolado ou associado na sintomatologia (OR 2,41; IC95%=2,13-2,72) e os óbitos no desfecho (OR:2,74; IC95%=2,57-2,92) tiveram mais chance de terem a confirmação para a COVID-19. Conclusão: os determinantes para a confirmação dos casos notificados demonstraram a importância de sintomas clínicos como a perda de olfato e paladar, assim como evolução para óbito como desfecho.
Basinophorous Statue for Meryptah and Ruiu in Glencairn Museum
Authors: Wegner Jennifer Houser
Published: November 2022

Statues comprised of an individual kneeling at the edge of an offering basin make their appearance as early as the Middle Kingdom. This is a relatively rare type of statuary with only several dozen examples known. These basi- nophorous statues promised their owners eternal refreshment. A previously unpublished example is presented here. A chantress of Amun named Ruiu and her husband Meryptah, who held a series of high-status offices during the reign of Amenhotep III, are the dedicants of this basin. This article suggests that the Meryptah mentioned on this basin may be the same as the Meryptah attested on other monuments from Amenhotep III’s reign.

الملخص

تظهرالتماثيلالمكونةمنفردراكععلىحافةحوضقرابينمنفترةالدولةالوسطىبمصرالقديمة.إنهذانوعنادرنسبًيامنالتماثيل،مع وجودعشراتالأمثلةالمعروفةفقط.وقدضمنتهذهالتماثيللأصحابهاالقرابينالأبدية.يتمتقديممثالغيرمنشورسابًقاهنامنهذا النوع من التماثيل. ان هذا التمثال يمثل منشدة للإله آمون تُدعى رويو وزوجها مريبتاح، اللذان كانا يشغلان سلسلة من المناصب الرفيعة المستوى في عهد أمنحتب الثالث. يقترح هذا المقال أن مريبتاح المذكور في هذا التمثال قد يكون هو نفسه مريبتاح الذي يمثل على آثار أخرى

من عهد أمنحتب الثالث.
Produções do Mestrado Profissional em Enfermagem na Atenção Primária à Saúde: Inovação na gestão e no cuidado em saúde e enfermagem
Authors:   Elisangela Argenta Zanatta, Martinazzo Aline Fagundes Venturin , Dall’Agnol Andreia Cristina ,   Carine Vendruscolo, Korb Arnildo , Vendruscolo Carine , Argenta Carla , Cabral Danielle Bezerra , Zocche Denise Antunes de Azambuja , Adamy Edlamar Kátia , Zanatta Elisangela Argenta , Hermes Jacqueline , Araújo Juliana Andréia Duarte , Bauermann Kaciane Boff , Zanatta Leila , Trindade Letícia de Lima , Ferraz Lucimare , Schoeninger Maiara Daís , Scaratti Maira , Neiss Mariluci , Zanatta Paola Franceschi , Ascari Rosana Amaora , Zanotelli Silvana dos Santos , Fincatto Suellen , Moraes Vanessa Correa de ,   Denise Antunes de Azambuja Zocche,   Leila Zanatta,   Rosana Amora Ascar
Published: November 2022

Esta obra compreende o reflexo de uma estratégia proposta de qualificação das ações de produção intelectual do MPEAPS, partindo das oficinas de planejamento estratégico realizadas ao longo do ano de 2020. Tais oficinas tinham como objetivo pensar meios de atingir as metas propostas pelo Relatório de Ações Corretivas que foram pensadas a partir dos elementos que emergiram na última Avaliação de Meio Termo da CAPES, na qual foram indicando os pontos considerados a serem melhorados pelo Programa de Pós-graduação em Enfermagem (PPGEnf), desde a avaliação do Mestrado Profissional em Enfermagem na Atenção Primária à Saúde (MPEAPS). Destes, foram avaliadas a qualidade da produção intelectual (bibliográfica e técnica) do corpo docente permanente com discentes, qualidade das atividades de pesquisa e da produção intelectual (bibliográfica e técnica) do corpo docente permanente do PPGEnf. Para atingirmos as melhorias necessárias à qualificação das atividades de pesquisa e da produção intelectual (bibliográfica e técnica) do corpo docente permanente do programa Produção de livro, o colegiado de professores definiu algumas ações, entre elas a construção de uma série de E-book’s sobre a elaboração dos produtos de cada turma do MPEAPS. Neste exemplar são oferecidas as produções tecnológicas oriundas dos trabalhos de conclusão de curso de dez mestres em enfermagem. Está dividido em três partes, a saber: na primeira são abordados os produtos inovadores desenvolvidos do mestrado profissional em enfermagem na atenção primária à saúde. Na segunda é apresentado o enfoque investigativo da produção das tecnologias e, na terceira, é destacado o protagonismo da enfermagem na produção de tecnologias.
Hanging-out-knowing
Authors: Pyyry Noora
Published: November 2022

In this paper, I approach knowing as a spatial practice of dwelling with one’s affective landscapes of inquiry to think with Erin Manning’s idea of research-creation as immanent critique. ‘Landscape’ is re-defined in a nonrepresentational frame to include the various materialities with which we sense and see. To approach research-creation as a joint-action with the landscape, I turn to my native language, Finnish, in which being is referred to as pre-individual with the passive form of ‘to be’: ollaan. I build the argument by discussing my research with young people on their hanging out practices. Movement without destination, attuning to the landscape, can be taken as an energizing technique of relation: an encouragement to follow the call of the unfolding world. In this experimental way of being together, new worlds and selves emerge in encounters. ‘Hanging-out-knowing’ arises from moments of hesitation that challenge what is known.
Genetic divergence at species boundaries of the dolphinfish (Coryphaena hippurus) in the Tropical Eastern Pacific
Authors: Ochoa-Zavala Maried , Diaz-Jaimes Pindaro , Ortega-García Sofía , Galván-Magaña Felipe
Published: November 2022

Background

Marine species constitute commercially important resources, and knowledge about mechanisms that shape phylogeographic patterns and genetic structure provides valuable information for conservation. The dolphinfish, Coryphaena hippurus, is one of the most important species caught in the Tropical Eastern Pacific (TEP). However, the lack of consensus about the existence of genetically differentiated populations in the area has hindered the adoption of management strategies to ensure its viability.

Methods

We assessed genetic variation and phylogeographic structure using two mitochondrial genes and 14 nuclear DNA microsatellite loci. Population genetic tools were used to characterize the spatial distribution of genetic variation of C. hippurus in the TEP, evaluate the extent of connectivity between dolphinfish populations, infer potential barriers to gene flow, and test for signals of contemporary and historical demographic expansions.

Results

Mitochondrial DNA sequences showed genetic homogeneity across locations in the TEP, as well as a strong signal of population expansion dated to the late Pleistocene. In contrast, nuclear microsatellite markers resolved four genetically distinct groups with a remarked genetic differentiation between the most distant locations, at the northern and southern boundaries of the species’ range. High mean genetic diversity was found at all localities (Hs = 0.66–0.81). Notwithstanding, positive FIS and low effective population size (Ne = 77.9–496.4) were also recorded.

Conclusions

The distribution of genetic variation could be related to expansion-contraction cycles following seasonal temperature changes at transitional areas, promoting population subdivisions. However, we cannot rule out the effect of oceanographic dynamics to the observed patterns. Although this marine species remains highly abundant despite commercial exploitation, the low Ne values are of conservation concern and must be considered in fishery management plans.
Detrimental Effects of Traffic Noise in Traffic Policemen as Assessed by Auditory Brainstem Evoked Response: A Cross-sectional Observational Study
Authors: Kumar Manoj , Saini Abhishek , Gupta Nivedita , Vyas Sangeeta
Published: November 2022

Introduction: Loud noise is a global occupational health hazard with substantial social and physiological impacts, especially pronounced in traffic policemen who are engaged at heavy traffic junctions. Apart from its overt effect on sensorineural hearing, loud noise has been also implicated, albeit covertly, as a causative factor for disturbances in sleep, learning and depression. Due to the insidious nature of hearing impairment, manifestations are often masked and hence testing through Auditory Brainstem Evoked Response (ABER) should be resorted to, for assessment of functional status of auditory pathway objectively. Aim: To assess and compare the effect of traffic noise in traffic policemen with age matched apparently healthy males using ABER. Materials and Methods: The present study was a crosssectional, comparative type of observational research conducted in the Department of Physiology, SMS Medical College, Jaipur, Rajasthan, India, from June 2019 to May 2020, on 45 apparently healthy male traffic policemen, aged 25-40 years, engaged at heavy traffic junctions of Jaipur city, with an average field posting of five years or more. An equal number of age and sex matched apparently healthy subjects living in Jaipur city, were recruited as controls. Before commencing with the test procedure, ethical clearance was obtained from the institute’s ethics committee and research review board and written informed consent was obtained from all the participants. ABER assessment was done via RMS EMG SALUS 2C machine on each subject using click stimuli presented mono-aurally via an overhead headphone resulting in harvest of variables in form of absolute wave latencies (I to V) and Interpeak Latencies (IPL) (I-III, I-V and III-V). Unpaired Student’s t-test was used to derive the level of significance using Statistical Package for the Social Sciences (SPSS) version 16.0. Level of significance was set at p-value <0.05. Results: The results obtained in the present study demonstrated pronounced delay (p-value<0.01) in all absolute wave latencies (I to V) in both ears in traffic policemen. A statistically significant delay was also observed in IPL I-V (p-value<0.01) when a comparison of left ABER was made between traffic policemen and controls. Conclusion: The findings of the present study indicate that the hidden footprints of loss in auditory acuity in traffic policemen exposed to traffic noise can be unearthed objectively via using ABER assessment and therefore periodic ABER assessment along with usage of preventive equipment should be the strategy for prevention of imminent hearing loss.
Prevalence of Congenital Colour Vision Deficiency in Belagavi, Karnataka, India: A Hospital-based Cross-sectional Study
Authors: Warad Chethana , Wani Radhika , Singh Ruchi
Published: November 2022

Introduction: Colour vision deficiency is a common ocular disorder, but it often goes unnoticed due to lack of awareness and screening programmes. If detected early in life, it can help people choose suitable career paths and genetic counselling can help reduce the birth of colour-blind children and future disappointments in life. Aim: To determine the prevalence of congenital Colour Vision Deficiency (CVD) among the general population in Belagavi at a tertiary level hospital and to spread awareness regarding CVD. Materials and Methods: This was a hospital-based crosssectional study, conducted at Jawaharlal Nehru Medical College, Belagavi, Karnataka, India (tertiary care hospital), from February 2022 to July 2022. The study population constituted 3131 people who visited the Ophthalmology Outpatient Department for routine eye examinations. A detailed ophthalmological examination was done, and colour vision was tested using Ishihara’s (38 plate) pseudoisochromatic test. Data was analysed using statistical software version 4.2.1 and Microsoft excel. Results: The mean age of the study population was 40.74±15.86 years. The overall prevalence of congenital CVD was 150 (4.79%). The prevalence of congenital colour vision defects was 13 (0.9%) in females, and 137 (8.12%) in males (p-value <0.001). Deuteranomaly was the most common type of congenital CVD, found among 88 (58.67%), followed by protanopia among 28 (18.67%), followed by protanomaly and deuteranopia, each accounting for 17 (11.33%). Conclusion: The prevalence of CVD among people belonging to the Belagavi district was remarkable. The p
Childhood neglect is associated with low affect and high stress in habitual alcohol drinkers
Authors: Peterson Hope , Laurienti Paul J. , Rejeski W. Jack , Fanning Jason , Gauvin Lise
Published: November 2022

Objective:  Adverse childhood experiences, ranging from childhood trauma to neglect or mistreatment, show associations with alcohol dependence in adulthood. Alcohol researchers have not yet clearly demonstrated the potential impact of childhood maltreatment on everyday drinking in alcohol consumers who do not have an alcohol use disorder (AUD). This study examined whether a history of childhood neglect results in differential ratings of stress, affect, and desire to drink, during typical alcohol consumption in moderate to heavy drinkers without an AUD.

Methods:  The parent study from which these analyses were generated recruited overall healthy, albeit moderate to heavy alcohol users who fell above National Institute on Alcohol Abuse and Alcoholism (NIAAA) classifications for low-risk drinking. Childhood Trauma Questionnaire (CTQ) responses were collected, and real-time surveys were collected in participants’ natural environments approximately every three hours between 9 a.m. and 9 p.m. using iPhones equipped with a study-created application probing stress, affect, and desire for alcohol, while participants followed their typical drinking routine (3 days) and during a brief period of imposed abstinence (3 days).

Results:  Thirty-six participants averaging 41 years of age and consuming an average of 17 (±5) drinks per week participated in this study. CTQ responses showed low prevalence of childhood abuse, but moderate to high emotional (M = 17.39, SD = 6.77) and physical neglect (M = 11.11, SD = 3.31) scores. Multilevel modeling revealed significantly higher stress and lower affect ratings among participants reporting higher physical neglect. Alcohol consumption was significantly associated with decreased stress, and increased affect and desire for alcohol. A significant interaction showed that as childhood physical neglect ratings increased, the benefits observed following drinking (of decreased stress, and increased affect and desire for alcohol) were reduced.

Conclusions: These results suggest that moderate to heavy healthy daily drinkers with histories of greater childhood physical neglect experience poorer mood and higher stress on a daily basis, with smaller improvement experienced from drinking alcohol. Among moderate to heavy daily drinkers without an AUD, those with greater childhood physical neglect experience poorer mood and higher stress on a daily basis, and have smaller improvements in stress, affect and desire while/following drinking alcohol than those with less childhood physical neglect.
Mapping of Micronutrients in Soils of Kishtwar District (Jammu and Kashmir) - A GIS Approach
Authors: Wani Owais Ali , Sharma K. R. , Kumar Shamal Shasang , Sharma Vikas , Kumar Vinit Vinay , Kumar Shavneel
Published: November 2022

A study was conducted to evaluate the status of DTPA extractable micronutrients of Kishtwar district soils and generate their prediction maps. The Kishtwar district of Jammu and Kashmir covers an area of 7737 sq. km. and falls in the temperate zone of the state. It is an upland valley in the northeast corner of the Jammu region. A total of 167 soil samples were collected from the entire Kishtwar district in a stratified random manner. The digitization and generation of maps were carried out with ArcGIS 10.0 software following Inverse distance weight (IDW). DTPA-Zn content of soils of Kishtwar varied widely as low as 0.13 mg Zn kg-1 and as high as 1.6 mg Zn kg-1 with a mean value of 0.64 mg Zn kg-1. DTPA ranged from 0.11 mg Cu kg-1 to 2.3 mg Cu kg-1 with a mean value of 0.77 mg Cu kg-1. DTPA-Fe ranged from 5.40 mg Fe kg-1 to 42.4 mg Fe kg-1, with a mean value of 22.05 mg Fe kg-1. DTPA- Mn ranged from 7.4 mg Mn kg-1 to 36.2 mg Mn kg-1 with a mean value of 18.59 mg Mn kg-1. Available boron (B) ranged from 0.05 to 3.6 ppm with a mean value of 0.70 ppm. Among micronutrients tested, Cu, Zn and B were mainly deficient; a regular supply of organic matter and pH correction is advised. Micronutrient deficiency and erosion are major hindrances in the agriculture of the district. The spatial maps on micronutrient status created throughout the study will be useful for farmers or researchers for the site-specific repair of nutrient deficiency and for assisting farmers in choosing the amount and type of nutrient to apply for the best results.
Voriconazole Associated Hypertension: A Case Report
Authors: Tuo Lin , Luo Tingting , Yang Xingxiang
Published: November 2022

Objective: The study report a case of a young female with candida tropicalis and candida krusei infection who developed severe hypertension after she had repeated received voriconazole for few days.

Case Presentation: A 23-year-old female was admitted to hospital because of recurrent urinary tract infection. She underwent horseshoe nephrectomy, extracorporeal lithotripsy treatment and double J-tube placement in the past 5 years. After multiple surgeries, she developed recurring fungal urinary tract infections and underwent anti-infective treatment. Twenty days ago, the patient developed chills, fever, dizziness, fatigue, urinary tract irritation signs and bilateral low back pain. Urine culture suggests Candida croco (resistant to fluconazole). After taking antifungal therapy with voriconazole 300 mg q12h, the patient experienced an unexplained increased blood pressure and transient loss of consciousness.

The patient began to experience an increase in blood pressure (140-160/90-100 mmHg) on the second day of voriconazole treatment. After 5 days of taking voriconazole, the patient developed fatigue, dizziness and blurred vision with persistent hypertension (150/100 mmHg), and temporary loss of consciousness and syncope on day8, when blood pressure was measured at 175/95 mmHg.

Conclusion: This case illustrates that acute blood pressure elevation may manifest in patients taking normal doses of voriconazole, which deserves the attention of clinicians.
Are Patient Satisfaction Instruments Harming Both Patients and Physicians?
Authors: Richman Barak D. , Schulman Kevin A.
Published: November 2022

In this Viewpoint, Richman and Schulman argue that patient satisfaction surveys may not actually reflect clinical performance or assist efforts to improve patient experience and are not useful tools to measure physician performance.
Enhancing Civic Engagement in Communities With Health Disparities
Authors: Cooper Lisa A. , Vincent Christina , Crayton Kareem
Published: November 2022

This JAMA Forum discusses enhancing civic engagement in the US and provides examples of how health equity leaders can help promote civic engagement in communities with health disparities.
Development of a Clinical Risk Score Prediction Tool for 5-, 9-, and 13-Year Risk of Dementia
Authors: Ren Lina , Liang Junxian , Wan Feng , Wang Yongjun , Dai Xi-jian
Published: November 2022

Importance

Although researchers have devoted substantial efforts, money, and time to studying the causes of dementia and the means to prevent it, no effective treatment exists yet. Identifying preclinical risk factors of dementia could help prevent or delay its progression.

Objective

To develop a point risk score prediction model of dementia.

Design, Setting, and Participants

This study used a large UK population-based prospective cohort study conducted between March 13, 2006, and October 1, 2010. Data analysis was performed from June 7 to September 15, 2021. Individual analyses of time end points were concluded at the first dementia diagnosis during the follow-up period. The data were split into training and testing data sets to separately establish and validate a prediction model.

Main Outcomes and Measures

Outcomes of interest included 5-, 9-, and 13-year dementia risk. Least absolute shrinkage and selection operator and multivariate Cox proportional hazards regression models were used to identify available and practical dementia predictors. A point risk score model was developed for the individual prediction of 5-, 9-, and 13-year dementia risk.

Results

A total of 502 505 participants were selected; the population after exclusions for missing data and dementia diagnosis at baseline was 444 695 (205 187 men; mean [SD] age, 56.74 [8.18] years; 239 508 women; mean [SD] age, 56.20 [8.01] years). Dementia occurrence during the 13 years of follow-up was 0.7% for men and 0.5% for women. The C statistic of the final multivariate Cox proportional hazards regression model was 0.86 for men and 0.85 for women in the training data set, and 0.85 for men and 0.87 for women in the testing data set. Men and women shared some modifiable risk and protective factors, but they also presented independent risk factors that accounted for 31.7% of men developing dementia and 53.35% of women developing dementia according to the weighted population-attributable fraction. The total point score of the risk score model ranged from −18 to 30 in men and −17 to 30 in women. The risk score model yielded nearly 100% prediction accuracy of 13-year dementia risk both in men and women.

Conclusions and Relevance

In this diagnostic study, a practical risk score tool was developed for individual prediction of dementia risk, which may help individuals identify their potential risk profile and provide guidance on precise and timely actions to promote dementia delay or prevention.
Optimal Timing of Anterior Cruciate Ligament Reconstruction in Patients With Anterior Cruciate Ligament Tear
Authors: Shen Xianyue , Liu Tong , Xu Shenghao , Chen Bo , Tang Xiongfeng , Xiao Jianlin , Qin Yanguo
Published: November 2022

Importance

The timing of surgery has been regarded as a key factor in anterior cruciate ligament reconstruction (ACLR), and early vs delayed ACLR remains a controversial topic.

Objective

To synthesize up-to-date published data from randomized clinical trials (RCTs) comparing early vs elective delayed ACLR for patients with ACL deficiency, in terms of clinical outcomes and complications.

Data Sources

The PubMed, Cochrane Library, and Web of Science databases were systematically searched until September 9, 2022.

Study Selection

All published RCTs comparing clinical and functional outcomes and complications associated with early ACLR vs elective delayed ACLR.

Data Extraction and Synthesis

Two reviewers independently extracted relevant data and assessed the methodological quality following the PRISMA guidelines.

Main Outcomes and Measures

Due to the clinical heterogeneity, the random-effects model was preferred. The primary outcomes were functional outcomes and complications. The Mantel-Haenszel test was used to evaluate dichotomous variables and the inverse variance method was used to assess continuous variables.

Results

This meta-analysis included 972 participants in 11 RCTs stratified by follow-up duration. The following factors did not differ between early and delayed ACLR: operative time (mean difference, 4.97; 95% CI, −0.68 to 10.61; P = .08), retear (OR, 1.52; 95% CI, 0.52-4.43; P = .44), and infection (OR, 3.80; 95% CI, 0.77-18.79; P = .10). There were also no differences between groups in range of motion, knee laxity, International Knee Documentation Committee (IKDC rating scale), and Tegner score. IKDC score (mean difference, 2.77; 95% CI, 1.89-3.66; P < .001), and Lysholm score at 2-year follow-up (mean difference, 2.61; 95% CI, 0.74-4.48; P = .006) significantly differed between early and delayed ACLR. In addition, the timing of surgery was redefined in the included RCTs and subgroup analyses were performed, which validated the robustness of the principal results.

Conclusion and Relevance

This systematic review and meta-analysis found that early ACLR was not superior to delayed ACLR in terms of most factors analyzed, except for IKDC and Lysholm scores. This information should be available to patients with ACL deficiency and clinicians as part of the shared decision-making process of treatment selection.
Perioperative Immune Checkpoint Inhibition in Early-Stage Non–Small Cell Lung Cancer
Authors: Desai Aakash P. , Adashek Jacob J. , Reuss Joshua E. , West Howard (Jack) , Mansfield Aaron S.
Published: November 2022

Importance

Although cancer-related mortality continues to decline, lung cancer remains the No. 1 cause of cancer deaths in the US. Almost half of the patients with non–small cell lung cancer (NSCLC) are diagnosed with early-stage, local or regional disease and are at high risk of recurrence within 5 years of diagnosis.

Observations

Immune checkpoint inhibitors (ICIs) have improved outcomes for patients with metastatic NSCLC and have recently been tested in multiple clinical trials to determine their efficacy in the neoadjuvant or adjuvant setting for patients with local or regional disease. The landscape for perioperative ICIs in lung cancer is evolving rapidly, with recently reported and soon to mature clinical trials; however, the recent data highlight the potential of ICIs to increase response rates and decrease rates of relapse in early stages of lung cancer. Concurrently, novel applications of cell-free DNA may guide perioperative management strategies.

Conclusions and Relevance

This article reviews the various approaches of incorporating perioperative use of immunotherapeutic agents for the treatment of early stages of NSCLC.
Trends in Incidence and Mortality of Larynx Cancer in the US
Authors: Divakar Prashanthi , Davies Louise
Published: November 2022

Importance

Larynx cancer is associated with considerable morbidity for patients and has a high mortality rate. Historical analyses showed that the incidence of larynx cancer was decreasing but the mortality was not similarly improving.

Objective

To assess whether incidence and mortality trends in larynx cancer in the US have improved.

Design, Setting, and Participants

This cohort study used population-based data from the Surveillance, Epidemiology, and End Results Program database for patients older than 18 years who were diagnosed with laryngeal cancer between January 1, 1986, and December 31, 2018. Data were analyzed from May 1, 2021, to May 31, 2022.

Main Outcomes and Measures

The main outcomes were incidence and mortality of larynx cancer by sex, subsite, and patterns of surgical treatment.

Results

Among 40 850 US patients with larynx cancer diagnosed from 1986 to 2018 (80.4% male), the incidence of larynx cancer decreased 55% from 5.00 per 100 000 people (95% CI, 4.70-5.32 per 100 000 people) to 2.26 per 100 000 people (95% CI, 2.11-2.42 per 100 000 people). During the same period, mortality decreased only 43% from 1.59 per 100 000 people (95% CI, 1.53-1.64 per 100 000 people) to 0.89 per 100 000 people (95% CI, 0.86-0.92 per 100 000 people). This corresponds to a 25% relative increase in case-fatality rate. Examination by stage showed a decrease in the incidence of localized disease at diagnosis of 40% from 2.65 per 100 000 people (95% CI, 2.44-2.89 per 100 000 people) to 1.60 per 100 000 people (95% CI, 1.45-1.76 per 100 000 people) from 1986 to 2002 and of 45% from 2.15 per 100 000 people (95% CI, 1.98-2.34 per 100 000 people) to 1.19 per 100 000 people (95% CI, 1.08-1.31 per 100 000 people) from 2005 to 2018. Distribution of larynx cancer by subsite remained stable, with most cases affecting the glottis. The proportion of patients receiving surgery as their first course of treatment decreased regardless of stage at presentation.

Conclusions and Relevance

In this cohort study, between 1986 and 2018, the incidence of larynx cancer decreased in the US, primarily because of the decrease in the incidence of localized disease. Mortality did not decrease similarly, resulting in an increased case-fatality rate overall. Encouraging earlier referrals for cancer concern, focusing resources where larynx cancer rates remain highest, renewing attention to research on new biologic causes of different tumor biologic characteristics, and conducting trials to directly compare treatments may help reverse this trend.
Harmonizing results of ataxia rating scales: mFARS, SARA, and ICARS
Authors: Rummey Christian , Harding Ian H. , Delatycki Martin B. , Tai Geneieve , Rezende Thiago , Corben Louise A.
Published: November 2022

The ever‐increasing body of ataxia research provides opportunities for large‐scale meta‐analyses, systematic reviews, and data aggregation. Because multiple standardized scales are used to quantify ataxia severity, harmonization of these measures is necessary for quantitative data pooling. We applied the modified Friedreich Ataxia Rating Scale (mFARS), the Scale for the Assessment and Rating of Ataxia (SARA), and the International Cooperative Ataxia Rating Scale (ICARS) to a large cohort of people with Friedreich's ataxia. We provide regression coefficients for scale interconversion and discuss the reliability of this approach, together with insights into the differential sensitivities of mFARS and SARA to disease progression.