bluuebunny/crossref_metadata_2025 huggingface dataset:
An Integrated Stepwise Approach to the Treatment of Graft Disease in a Patient with an Implanted Iris Lens Diaphragm and Concomitant Postkeratoplastic Ametropia (Clinical Case)
Authors: Sinitsyn M. V. , Pozdeyeva N. A. , Terent’eva A. E.
Published: October 2023

The purpose: to analyze the clinical and functional results of the complex staged treatment of graft disease in patient with an implanted iris lens diaphragm and concomitant postkeratoplastic ametropia using descemet’s stripping endothelial keratoplasty using a femtosecond laser (FS-DSEK) and MyoRing implantation into a corneal graft using a femtosecond laser on the example of a clinical case. Methods. Patient M., 51 years old, was admitted with a diagnosis of the left eye: corneal transplant disease, condition after penetrating keratoplasty, iridoartifakia, avitria, optic nerve subatrophy, high myopia. To treat the graft disease, the patient underwent FS-DSEK using a FemtoVisum 1 MHz (Troitsk, Russia). Twelve months after FS-DSEK to correct irregular postkeratoplastic astigmatism and concomitant high-grade myopia detected after restoration of the transparency of the penetrating corneal graft, the MyoRing was implanted into the penetrating corneal graft using a femtosecond laser. Results. After performing FS-DSEK, the transparency of the penetrating corneal graft was completely restored, visometry, refractokeratometry, and keratopachymetric data were stabilized by 6 months after the operation. 12 months after FS-DSEK, uncorrected visual acuity (UCVA) increased from 1.6 to 1.2 LogMAR, best corrected visual acuity (BCVA) increased from 1.6 to 0.8 LogMAR. Loss of endothelial cell density of the posterior layered graft was 27.4 %. MyoRing implantation into a penetrating corneal graft made it possible to significantly increase the UCVA from 1.3 to 0.3 LogMAR and the BCVA from 0.8 to 0.2 LogMAR. The spherical component of refraction decreased from -6.25 to -0.75 D, the cylindrical component of refraction — from -9.25 to -1.25 D, the regularity, sphericity of the corneal graft and its biomechanical properties increased (corneal resistance factor increased from 8.2 to 9.4 mm Hg, corneal hysteresis — from 7.9 to 9.1 mm Hg). Conclusion. A complex staged technique of descemet’s stripping endothelial keratoplasty using a femtosecond laser followed by MyoRing implantation into the corneal graft using a femtosecond laser is an effective and safe method for treating graft disease in a patient with an implanted iris lens diaphragm and concomitant postkeratoplastic ametropia.
Frailty phenotype in chronic obstructive pulmonary disease patients: prevalence and relation to disease severity
Authors: Abdelwahab H. W. , Shata H. M. , Abdelghany D. A. , Elmaria M. O.
Published: October 2023

Frailty is considered a high risk for falls, disability, hospitalization, and mortality in geriatric and certain chronic-disease populations. So, this study was planned to determine the prevalence of frailty phenotype in Chronic obstructive pulmonary disease (COPD) patients. Methods. 70 stable COPD patients were included in this study. Age, comorbidities (The FRAIL (Fatigue, Resistance, Ambulation, Illness, and Loss of weight) scale, BODE index, and modified Medical Research Council dyspnea score (mMRC) were recorded. In addition, each patient performed the Six-minute walk test (6-MWT) and underwent a pulmonary function test. Results. Frailty was detected in 37.3% of studied patients. However, 43.1% were classified as pre-frail. The presence of frailty was not significantly associated with the age of studied patients (p = 0.7). Comorbidities were significantly associated with frailty (p = 0.009). Also, the BODE index was significantly higher among patients with frailty (p < 0.001). Frailty was significantly associated with forced expiratory volume in 1 second, residual lung volume/Total Lung Capacity, and GOLD (Global Initiative for Chronic Obstructive Lung Disease) classification of COPD (p = 0.001; p = 0.003; p = 0.003 respectively). Frailty was significantly associated with 6-MWD and Borg scale difference (Lowest 6-MWD, highest Borg scale difference were detected in frail patients (p = 0.008; p = 0.001). Conclusion. Frailty is frequent among COPD patients. The presence of frailty is related to disease severity and functional impairment. Evaluation of frailty should be considered as a part of COPD assessment in clinical practice.
Course of sarcoidosis in patients treated with systemic corticosteroids
Authors: Vizel A. A. , Avdeev S. N. , Vizel I. Yu. , Shakirova G. R. , Vlasenko A. E.
Published: October 2023

The treatment of sarcoidosis remains uncertain despite 70 years of studies. The conventional approach is to initiate corticosteroids in individuals who require treatment. However, to date, there are no strict dosing regimens for systemic corticosteroids (SСS), and patients who were treated with SСS develop relapses more frequently than those who have not received these drugs. The aim of this work was to evaluate the course and outcomes of pulmonary sarcoidosis in patients who were prescribed systemic corticosteroids. Methods. The study was retrospective and noninterventional. 493 (32.5%) of 1,518 patients with sarcoidosis were prescribed corticosteroids during follow-up. Only 333 cases were selected because they had histologic confirmation and follow-up of 1 year or more. The data at the time of diagnosis and at the time of analysis were compared (patients remained under the supervision of the same physicians thereafter). Results. After at least one year of follow-up, the positive effect of SCS (resolution or stabilization of the process) was achieved only in half of the cases, while the rest of the patients required more courses of SCS or the use of alternative drugs. Worsening was more common when multiple organs were involved, when SCS were administered immediately after diagnosis without a follow-up period, and when the duration of the first course of hormone therapy was less than 7 months. 33.6% of patients treated with SCS had clinically significant adverse events (AEs), and 13.2% had to discontinue or replace one hormonal drug with another. Older age and repeated courses of SCS were associated with the development of fibrosis, whereas transition to second-line drugs was not. Conclusion. SCS remain the first-line drugs in the treatment of sarcoidosis. The analysis performed allows us to recommend them after an observation period (if the patient’s condition allows it) and for at least 6 months. In case of exacerbation or recurrence of sarcoidosis after treatment with SCS, subsequent therapy with second-line drugs is more effective that a repeated course of SCS.
Composition of bacterial microbiome in sputum of patients with localized forms of pulmonary tuberculosis
Authors: Druzhinin V. G. , Baranova E. D. , Demenkov P. S. , Zakharova Ju. V. , Lavryashina M. B. , Larionov A. V. , Matskova L. V. , Shabaldin A. V. , Pyanzova T. V.
Published: October 2023

Recent studies have shown that the respiratory bacterial microbiome has an impact on the development of pulmonary tuberculosis. Changes in the composition of the microbiome have been associated with the pathogenesis of Mycobacterium tuberculosis infection, response to therapy, and clinical outcomes of the disease. To date, the composition of the respiratory microbiome has not been studied in patients with localized forms of pulmonary tuberculosis. Methods. In the present study, the taxonomic composition of the sputum microbiome of 14 patients with localized forms of pulmonary tuberculosis (tuberculomas) and 14 healthy donors in the comparison group was analyzed by sequencing (NGS) of the V3 – V4 region of the bacterial gene encoding 16S rRNA. Results. The sputum microbiomes of the patients and the control group did not have significant differences in the species richness index (Shannon). However, the patients showed a decrease in the uniformity index, another parameter of alpha diversity. Bacterial community structures (beta diversity) did not differ significantly between patients with localized forms of tuberculosis and healthy subjects. In patients with limited forms of tuberculosis, contrary to the decrease in the content of representatives of the phyla Fusobacteria, TM7, Tenericutes, Spirochaetes, and SR1, and of the genera Dialister, Mycoplasma, and Filifactor in the sputum, no clear dominance of any bacterial taxon was observed. Conclusion. Certain alpha and beta diversity parameters that characterize the sputum microbiome of patients with localized forms of pulmonary tuberculosis need to be confirmed in independent large-scale studies to further understand the role of the sputum microbiota in the development of localized forms of pulmonary tuberculosis. Determination of Prevotella titers in the sputum of these patients holds promise for the diagnosis of localized forms of pulmonary tuberculosis and the search for their genomic markers.
Blood periostin/procalcitonin index in patients with asthma and asthma-COPD overlap
Authors: Trofimov V. I. , Baranov D. Z. , Mineev V. N.
Published: October 2023

The significant prevalence of asthma and asthma-COPD overlap (ACO) necessitates further rationalization of diagnostic and treatment approaches and emphasizes importance of studying the pathogenesis of bronchial obstructive diseases. Well-known markers of allergic and infectious inflammation such as periostin and procalcitonin, respectively, have shown their utility in pulmonology. The aim of this study is to analyze the diagnostic value of blood periostin/procalcitonin index as a complex parameter reflecting both allergic and non-allergic inflammation. Methods. First, we calculated blood periostin/procalcitonin index. Then we compared this index between two groups using the Mann – Whitney test. Results. Patients with non-allergic asthma had lower blood periostin/procalcitonin index compared to the patients with allergic asthma (p = 0.003). Blood periostin/procalcitonin index correlated well with diagnosis in patients with asthma and ACO in our clinical cases. Conclusion. Blood periostin/ rocalcitonin index has demonstrated its clinical utility as a complex inflammatory parameter. Its high values indicate active allergic inflammation. This index can be used to correct glucocorticoid and antibacterial treatment.
Significance of N-acetylcysteine in clinical practice
Authors: Leshchenko I. V. , Esaulova N. A.
Published: October 2023

N-acetylcysteine (NAC) is a mucolytic and antioxidant with a variety of properties. The clinical use of NAC spans more than 35 years, during which the emphasis has been on a multifaceted action and broad spectrum of therapeutic indications. Information is available on the efficacy of NAC in the prevention of contrast-induced nephropathy, studies on the role of NAC in the treatment of pulmonary and coronary disease, etc. The purpose of this review is to analyze the efficacy and safety of NAC in respiratory clinical practice. Conclusion. NAC is a drug with a unique variety of properties and treatment options. The drug has proven its efficacy and safety in real pulmonology practice.
Pulmonary sequestrations
Authors: Bazhenov A. V. , Motus I. Ya. , Berdnikov R. B. , Romahin A. S.
Published: October 2023

Congenital lung malformations account for 2.2 – 6.6% of all congenital abnormalities of the lungs. This is a pretty rare problem as compared to acquired lung diseases. Pulmonary sequestrations account for 0.15 – 1.8% in the incidence of all lung malformations, occupying the second place after the complex abnormalities called “lung agenesis-hypoplasia”. Pulmonary sequestrations are common in children and adolescents so one could encounter them in pediatric practice. But pulmonary sequestrations may be associated with insignificant symptoms or even be asymptomatic in selected pediatric cases. Thereby, adult general practitioners, pulmonologists, and thoracic surgeons may encounter such patients. The aim. Review had the purpose to inform the general practitioners, pulmonologists, and thoracic surgeons about pulmonary sequestrations and their diagnostic, clinics course, and treatment. Conclusion. There is a wide range of congenital abnormalities of human body. Pulmonary sequestrations are only a part of this huge problem. But modern medicine has a vast selection of methods for revealing and treating these conditions (including minimally invasive surgery).
Fungal infections in patients with progressing COVID-19: pathomorphology and description of clinical cases
Authors: Mnichovich M. V. , Soldatova A. A. , Usmanov S. I. , Shiripenko I. A. , Sidorova O. A. , Lozina M. V. , Snegur S. V. , Pavlova Ju. G. , Baklanov P. P. , Kozeev V. M.
Published: October 2023

Invasive pulmonary mycoses are a common complication of severe COVID-19 (COronaVIrus Disease 2019) and are characterized by rapid spread and high mortality. It is especially important to study the epidemiology and pathomorphology of fungal superinfection in order to understand the main vector of the diagnosis and treatment of this complication. The aim of this paper is to consider aspects of the epidemiology, pathomorphologic picture, and clinical manifestations of invasive pulmonary mycoses associated with COVID-19. Clinical cases of fungal superinfections (candidiasis, aspergillosis) associated with COVID-19 in patients receiving appropriate therapy were presented. Results of autopsy examination and light microscopy with routine staining were analyzed. Macroscopic assessment of lesions and histological examination revealed morphological multiorgan changes typical of the combination of fungal (candidiasis, aspergillosis) and viral infection (COVID-19). Conclusion. The presented data of post-mortem examination are important for both science and clinical practice as they form the basis for finding new ways of treating patients with comorbid pathology and developing a prognostic algorithm.
Líderes locales y segregación en asentamientos periurbanos durante la COVID-19
Authors: Martinez Ramirez Lesly Janet , RUIZ LÓPEZ CINTHIA
Published: October 2023

La pandemia por la COVID-19 resaltó las múltiples carencias en que viven muchos habitantes. A nivel mundial, las principales preocupaciones durante ese periodo han sido los alimentos, el desempleo, el acceso a servicios básicos o la violencia, entre otras. En pocas ocasiones se ha centrado el interés en los asentamientos periurbanos de las ciudades intermedias mexicanas, urbanizados de manera segregada. Los líderes locales fueron actores importantes para contrarrestar los efectos. El artículo explora su papel y sus estrategias durante las etapas iniciales de la pandemia, reconociendo los cambios en el proceso de segregación en dos asentamientos periurbanos de una ciudad intermedia mexicana (Morelia, Michoacán). Entrevistando a los líderes de estos territorios se encontró que fueron claves en la gestión de alimentos y artículos sanitizantes. Los vínculos de estos actores modificaron la segregación durante la pandemia, al fomentar la cooperación al interior, pero sus valorizaciones incrementaron la diferenciación.
Identificação das injustiças sociais e ambientais através dos avanços de modelagem cartográfica ambiental da Escola Brasileira e Luso Brasileira
Authors: Costa Marcelo , Aparecida Zacharias Andréa , Cunha Lúcio , Dos Santos Marcilene
Published: October 2023

A justiça social e ambiental são temas amplamente discutidos em diversos setores da sociedade e campos políticos. Essas questões estão relacionadas à distribuição desigual de recursos e oportunidades, especialmente em áreas urbanas, como renda, acesso à educação, moradia, tratamento de água e esgoto, entre outros. Essa desigualdade contribui para uma sociedade injusta social e ambientalmente. Nesse contexto, o objetivo deste trabalho é analisar os avanços teórico-metodológicos da Escola Brasileira e Luso Brasileira no estudo da Vulnerabilidade Social e Ambiental e discutir a relação das áreas de maior vulnerabilidade com as áreas de injustiças sociais e ambientais. Essa relação é possível pois a metodologia utilizada pela Escola Brasileira e Luso Brasileira integra diversos fatores que representam as injustiças sociais e ambientais, como acesso a recursos e características socioeconômicas e físico-naturais numa perspectiva sistêmica.
Greenhouse crops of radish under organomineral fertilization sources in the Brazilian semiarid region
Authors: Gondim Ancélio Oliveira , Lira Renato Pereira de , Pereira Francisco Hevilásio Freire , Oliveira Neto Hélio Tavares de , Silva Francisco de Assis da , Lima Neto Joaquim Vieira
Published: October 2023

The cultivation of radish in an organic system has potential for production to such a degree that alternatives of cultivation have been used to improve productivity in relation to fertilization. Therefore, the objective of this work was to evaluate the effect of organomineral fertilization on gas exchange, growth, and production of radish. The experiment was carried in non-climatized greenhouse crop, with a metallic structure in form of arc, covered with 150 mm low-density polyethylene, in greater length-oriented East-Oste direction of Science and Technology Center of Federal University of Campina Grande, using the Crimson Gigante variety. The soil used experiment was fluvic neosol. The experimental design used was the completely randomized with three replications, using the Crimson Gigante variety. Seven treatments were used, which consisted of three doses of cattle manure (37.5; 75.0, and 150g per pot), three concentrations of biofertilizer (5; 10 and 15%), and mineral fertilization. This work analyzed the characteristics of growth, production, and gas exchange. The treatment (5% biofertilizer) provided greater height of the radish plants, however, the (75.0g manure per pot) resulted in a higher number of leaves. The concentration of 10% of the biofertilizer, obtained the largest diameter, fresh and dry matter of the tuberous root. The treatment presented higher fresh and dry matter of the leaves when compared with the other treatments. The use of organic fertilizers promoted greater production in the radish crop and can be used as an alternative to conventional fertilization.
The determinants of airline networks in the island regions of Japan
Authors: Takahashi Kantaro
Published: October 2023

This study aims to show the determinants of the airline’s networks in Japanese island regions. Transportation systems are generally needed for residents in island regions to maintain their livelihood. Meanwhile, it is also necessary for people who live in outside regions such as tourists. Therefore, the transportation systems would be significant to maintain both tourism industries and the social situations in many of islands in Japan. This study, first, applied the network analysis to verify the nexus of connections among the transportation network in island regions in Japan. Degree centrality was calculated, and the result shows that some islands which is well-known as the tourism destinations located in southern part of Japan obtained many of connections to other places including other islands, as well as the mainland. Then regression model with the result of network analysis was composed and estimated by maximum likelihood method. The outcome shows that the situations of island society such as aged problem and economy in the islands would be influenced to maintain the airlines, as well as the amount of tourism demand. From these results, this paper concluded that both internal situations of island society and the tourism demand would be important to maintain island’s transportation system.
Neuropedagogy of Communication-Imitation Opportunities for the Ukrainian English Teacher
Authors: Savchenko Oksana , Prystai Halyna , Hulych Mariia , Sobol Liliia , Stupnytska Halyna
Published: October 2023

The article tells about the problems of motivation, specificity and effectiveness of using chatbots by Ukrainian humanities students when studying English and, based on the analysis of sociological data, provides new recommendations for the English language teacher.
The purpose of the article is to define the problem of using new communicative-simulation opportunities of today's chatbots "from the inside", i.e. from the point of view of personal motivation of the participants of the educational process. This allowed us to understand the more general and invariant neuro-pedagogical mechanisms of the stimulation anthropomorphic environment and tools in English language learning.
The authors used sociological, statistical, modeling-predictive pedagogical methods in order to outline the real picture of students' use of chatbots in English studies on the basis of existing neuroscience theories and real student priorities and to provide general methodological recommendations for modeling communicative-simulation technology in linguistic pedagogy.
The main result of the article is to objectify the real neuropsychological picture of students' motivation in English-language communication in chatbots, as well as to present five-component gradation of scenarios for chatbots use by students with different levels of academic knowledge, personal pretensions and self-organization abilities.
The theoretical conclusions of the article consist in: a) confirmation and further development of already existing provisions on the use of simulation technologies; b) essays on Ukrainian specifics of using chatbots in English language learning in the context of the neuro-pedagogical approach; c) proving the thesis that English-language chatbots are used outside educational plans and are mostly an optional, spontaneous or personal intension tool in learning a foreign language.
Residing in the Periphery while Teaching in the Center of Nonprofit Management Education: Perspectives from a Strategic Communication Professor
Authors: Waters Richard D.
Published: October 2023

This essay describes my experiences as a nonprofit management education professor whose academic and professional backgrounds come from strategic communication. I highlight the teaching, service, and research stresses that I’ve experienced as a professor who doesn’t share the same theoretical perspectives as program directors and department chairs who come from public administration, business, and social work backgrounds. I write about these tensions not to vent or air dirty laundry but to encourage nonprofit management education programs to recruit tenured, tenure-track, and adjunct professors who have different backgrounds and actively bring them into key roles within the program in regards to strategic planning, evaluation, and administration.
What Were You Thinking? A Constructive Epistemology of Nonprofit Policy Development
Authors: Kushner Roland
Published: October 2023

This paper examines the challenges of teaching management policy development in nonprofit organizations through a pan-disciplinary “constructive epistemology.” The elements of the epistemology encompass sequential elements that go beyond problem-solving heuristics, and apply well to managerial policy development in nonprofit organizations. Those elements include Issue Identification, Stakeholder Recognition, Normative Desires, Conceptual Framing, Empirical Observation, Scenario Envisioning and Prescriptive Recommendation. I argue that each of these helps to frame policy problems, and together they provide a firm basis for developing policy and for reviewing its effects. The constructive epistemology is illustrated with a discussion of how nonprofits might develop policy around the prospect of receiving donations from morally suspect sources, the so-called “dirty money” problem.
Four Pivots: Reimagining Justice, Reimagining Ourselves and Designing for Belonging: How to Build Inclusion and Collaboration in Your Communities, Book Review
Authors: Pigza Jennifer M.
Published: October 2023

This book review weaves together summary, critique, and application possibilities of two texts: The Four Pivots: Reimagining Justice, Reimagining Ourselves (Ginwright, 2022) and Design for Belonging: How to Build Inclusion and Collaboration in Your Communities (Wise, 2022).
Od realności do wyobraźni. Ćwiczenia i warsztaty z uważności dla dzieci, młodzieży i dorosłych
Authors: Karolak Wiesław , Karolak Barbara
Published: October 2023

Książka Od realności do wyobraźni. Ćwiczenia i warsztaty z uważności dla dzieci, młodzieży i dorosłych może stanowić cenną pomoc dla nauczycieli, metodyków, studentów wielu specjalności pedagogicznych, edukacji artystycznej i arteterapii. Będzie przydatna dla wszystkich, którzy prowadząc zajęcia grupowe poszukują atrakcyjnych metod pracy, dających uczestnikom radość tworzenia i zwiększających efektywność działań twórczych. Autorzy skupiają się na świecie realnym, na przedmiotach, aby poprzez pracę z wyobraźnią dojść do podmiotowości. W sensie teoretycznym i praktycznym, proponują aktywności związane z twórczym rozwojem głównie dzieci i młodzieży ale również dorosłych. Książka zawiera szereg scenariuszy do realizacji działań profilaktycznych i interwencyjnych przy użyciu twórczego samorozwoju, twórczej terapii. Są to obszary związane z komunikowaniem się zarówno ze sobą, jak i z innymi. Publikacja składa się z czterech części. Pierwsza część to rozważania teoretyczne. Druga część Niecodzienna codzienność poświęcona jest istocie piękna łączącego się z subtelnością, wdziękiem i wytwornością. Trzecia część Przedmioty omawia świadome postrzeganie i istotę uwagi. Część czwarta publikacji to Poszukiwanie piękna. W tej części autorzy zachęcają do zbaczania z przyzwyczajeń percepcyjnych i instrumentalnego rozumowania. To odejście od postrzegania rzeczy i świata w sposób jednowymiarowy.
Influence of Irrigation Methods and Nano-fertilizers Application on the Yield of Transplanted Lowland Rice (Oryza sativa L.) in Periyar Vaigai Command Area of Madurai
Authors: Vasuki A. , Paulpandi V.K. , Singh R. Durai , Gurusamy A. , Mahendran P.P. , Sivakumar T. , Prabakaran K.
Published: October 2023

Background: Rice production and productivity must be increased despite water scarcity and deterioration of soil fertility by imbalanced fertilizer application. To meet the demand of the ever growing population, the production level must be increased to cope with minimum inputs and enhanced input-use efficiency. Efficient and effective method of irrigation and fertilizer application could address the emerging issue. Methods: The field study was conducted at the Agricultural College and Research Institute in Madurai to identify suitable irrigation methods and nutrient management practices with the aim of increasing the yield of rice under transplanted condition during Kharif 2022. The experiment was carried out in a split plot design with irrigation methods in the main plot and foliar spray of nano-fertilizers in combination with conventional fertilizers in the sub-plot. Result: Yield characters such as number of productive tillers m-2, panicle length (cm), panicle weight (g), number of grains and filled grains panicle-1 were recorded in addition to grain and straw yield (kg/ha). From this study it could be concluded that, irrigation through alternate wetting and drying along with combined application of 50% N and K through straight fertilizers + Nano N and K applied as foliar spray recorded higher yield attributes and yield of rice.
Ortorexia nerviosa y conductas de control del peso en estudiantes mujeres de Nutrición: un estudio correlacional
Authors:   , Herrera Besich Brunella
Published: October 2023

El objetivo del estudio fue determinar la relación entre la ortorexia nerviosa y las conductas de control de peso en estudiantes mujeres de nutrición de universidades privadas de Lima. La muestra estuvo conformada por 122 estudiantes entre 17 y 22 años que cursaban entre el primero y duodécimo curso de la carrera. Se realizó una encuesta online que contenía el consentimiento informado, los datos sociodemográficos, las preguntas de la escala TOS (Teruel Orthorexia Scale) y el check list Project EAT-III Survey. Se encontró que la ortorexia nerviosa (ON) se correlaciona negativamente con la dimensión de peso saludable, aunque dicha relación no fue significativa. No obstante, se pudo observar que la ON tiene una relación positiva y significativa con la conducta de control de peso no saludable y con la conducta de control de peso extrema. Estos hallazgos nos permiten verificar la importancia de que se realicen nuevos estudios sobre la ortorexia con la finalidad de identificarla adecuadamente y prever repercusiones en la salud mental de las futuras profesional del campo de la nutrición.
Orientación futura en estudiantes de secundaria de un colegio privado en Cañete
Authors:   , Lazo Archimbaud Jimena Anaines , Mancini Subauste Valeria Andrea
Published: October 2023

El objetivo del estudio fue describir la orientación futura en estudiantes de secundaria de un colegio privado en Cañete. Para tal fin, se desarrolló un estudio cualitativo con diseño fenomenológico, utilizando la entrevista enfocada como técnica de recolección de información y el análisis temático como estrategia de análisis. Participaron tres hombres y seis mujeres con edades entre los 15 a 17 años, matriculados en el 4to y 5to año de educación secundaria. Los resultados principales muestran que los participantes consideran los dominios académico y laboral como sus principales objetivos a corto y largo plazo respectivamente. De igual manera, consideran que los miedos y las esperanzas están enfocados principalmente en el dominio académico. Se concluye que los participantes privilegian orientaciones futuras vinculadas con la vocación de servicio, el bienestar personal y la formación familiar. Además, mencionan que la orientación futura se ha ido construyendo a lo largo del tiempo bajo la influencia indirecta del colegio, la familia y los pares.
Dinamika Harga Saham: Dampak dari Asset Growth, Net Profit Margin, ROI dan Islamic Social Reporting
Authors: Rachmania Sabilla Meyra , Arwani Agus
Published: October 2023

Harga saham merupakan harga sebuah saham yang berupa bukti pernyertaan modal dalam suatu perusahaan dan memiliki data yang cenderung berfluktuatif atau selalu berubah ubah. Penelitian ini bertujuan untuk mengetahui bagaimana pengaruh asset growth, net profit margin, return on investment dan islamic social reporting terhadap harga saham. Penelitian ini termasuk ke dalam jenis penelitian asosiatif kausal dengan pendekatan kuantitatif. Populasi dalam penelitian ini merupakan seluruh perusahaan perusahaan sektor properti dan real estate yang terdaftar di Daftar Efek Syariah periode 2018 – 2022 yang berjumlah 98 perusahaan. Teknik sampling dalam penelitian ini menggunakan teknik purposive sampling, dengan jumlah sampel sebanyak 14 perusahaan. Analisis data yang digunakan dalam penelitian ini adalah analisis statistik deskriptif, uji asumsi klasik, uji regresi linear berganda, uji t, uji F, dan koefisien determinasi. Berdasarkan hasil uji t (parsial), menunjukkan bahwa variabel asset growth tidak berpengaruh terhadap harga saham, variabel net profit margin berpengaruh negatif dan signifikan terhadap harga saham, sedangkan variabel return on investment dan islamic social reporting berpengaruh positif dan signifikan terhadap harga saham. Hasil uji F (simultan) menunjukkan bahwa variabel asset growth, net profit margin, return on investment, dan islamic social reporting berpengaruh secara simultan terhadap harga saham.
Pengaruh Sistem Akuntansi Keuangan Daerah Dan Sistem Pengendalian Internal Terhadap Kualitas Laporan Keuangan Pemerintah Daerah Kabupaten Pamekasan
Authors: Suci Pangestuning Ajeng Istifara , Wadhan Wadhan
Published: October 2023

Penelitian ini bertujuan untuk mengetahui pengaruh sistem akuntansi keuangan daerah dan sistem pengendalian internal terhadap kualitas laporan keuangan pemerintah daerah Kabupaten Pamekasan secara parsial dan simultan. Penelitian ini menggunakan metode kuantitatif dengan jenis penelitian asosiatif kausal. Penelitian ini dilakukan pada 35 SKPD yang berada di Kabupaten Pamekasan. Populasi dan sampel yaitu Kepala SKPD dan Kepala Bagian Keuangan SKPD dengan responden sebanyak 2 orang pada tiap instansi. Data yang digunakan pada penelitian ini data primer dengan penyebaran kuesioner. Teknik pengambilan sampel menggunakan purposive sampling dengan teknik analisis data menggunakan analisis regresi linier berganda, uji kualitas data, uji asumsi klasik, dan uji hipotesis dengan bantuan aplikasi SPSS 24. Hasil penelitian menunjukkan bahwa variabel sistem akuntansi keuangan daerah memperoleh nilai thitung > ttabel yaitu sebesar 4,914 > 1,670 dengan nilai signifikansi sebesar 0,000 < 0,05 yang artinya sistem akuntansi keuangan daerah secara parsial berpengaruh positif dan signifikan. Pada variabel sistem pengendalian internal memperoleh nilai thitung > ttabel yaitu sebesar 6,019 > 1,670 dengan nilai signifikansi sebesar 0,000 < 0,05, yang artinya sistem pengendalian internal secara parsial berpengaruh positif dan signifikan. Berdasarkan penelitian pada uji F memperoleh nilai Fhitung > Ftabel yaitu sebesar 114,849 > 3,15 dan nilai signifikan yaitu sebesar 0,000 < 0,05. Hasil dari penelitian ini menunjukkan bahwa H1, H2, H3, diterima yang artinya sistem akuntansi keuangan daerah dan sistem pengendalian internal berpengaruh positif dan signifikan terhadap kualitas laporan keuangan pemerintah daerah Kabupaten Pamekasan.
Antimalarial Potential of Fraction 5 from Ethanolic Leaves Extract of Artocarpus Altilis
Authors: Einstenia Kemalahayati  , Hilkatul Ilmi  , Agriana Rosmalina Hidayati  , Marsih Wijayanti  , Lidya Tumewu  , Suciati  , Achmad Fuad Hafid  , Widyawaruyanti Aty
Published: October 2023

Background: Artocarpus altilis leaf extract (AAL.E) was separated by VLC, and six fractions were obtained. Fraction 5 (AAL.E.5) showed antimalarial activity with an IC50 value of 3.71 µg/mL. Objective: This study aimed to determine the antimalarial activity of AAL.E.5 subfractions against P. falciparum, the mechanism of action against Plasmodium Falciparum Malate quinone oxidoreductase (PfMQO), and the active substances. Methods: The AAL.E.5 was separated by open-column chromatography and eluted with chloroform-methanol gradient elution in order of increasing polarity. The antimalarial activity of all subfractions was assessed using a lactate dehydrogenase (LDH) assay against P. falciparum and the mechanism of action of the PfMQO enzyme. The profiles of the most active subfractions were analyzed using High-Performance Liquid Chromatography (HPLC). Results: The separation of fraction 5 (AAL.E.5) yielded 11 subfractions (AAL.E.5.1–AAL.E.5.11). Screening antimalarial activity at 10 μg/mL in this subfraction showed that only five subfractions (AAL.E.5.6-AAL. E.5.10) inhibited P. falciparum and two subfractions (AAL.E.5.6 and AAL.E.5.10) inhibited the PfMQO enzyme. Only subfraction 6 (AAL.E.5.6) inhibited both, with IC50 values of 6.609 µg/mL and 20.34 µg/mL. The thin layer chromatography profile of AAL.E.5.6 revealed reddish-orange spots, indicating the presence of flavonoid compounds, and was also presumed from the UV-visible to HPLC chromatogram for band I in the 300 – 400 nm range and band II in the 240–285 nm range. Conclusion: Subfraction 6 has antimalarial activity against P. falciparum and is thought to have a mechanism of action in PfMQO. Based on the TLC, HPLC, and UV-Vis spectra, subfraction 6 was assumed to be a flavonoid.
Effectiveness of the CinQASE Web Integrated Learning Model to Train Higher Order Thinking Skills
Authors: Anwar Rahmat Saifuddin , Salam Abdul , Haryandi Surya , Rahman Nur Farahwahidah Abdul
Published: October 2023

The lack of training in higher-order cognitive thinking skills in physics makes most students of class XI MIPA in a high school in Marabahan unable to solve problems that require the ability to analyze (C4) and evaluate (C5) well. This study was intended to describe the effectiveness of using the web-integrated CinQASE learning model to train higher-order thinking skills in the C4 and C5 domains. This study used the pre-experimental one-group pretest-posttest design. The efficacy of the web-integrated CinQASE learning model to train higher-order thinking skills is calculated with the eta-squared effect size for a paired sample t-test. In contrast, the description of students' achievement in higher-order thinking is viewed from the percentage of the average score of the student learning outcomes test on items that have C4 and C5 domains. The results showed that using the model had moderate effectiveness (η2 = 0.94) and helped train students’ ability to think at a higher level, as shown by an increase in students’ achievement in higher-level thinking in the good category. Thereby, the use of the web-integrated CinQASE learning model can supply considerable benefits in training students’ higher-order thinking skills. These results also write down a practical need for teachers and schools to implement learning approaches that use the potential of technology to enhance learners’ higher-order thinking skills in the 21st century.
Genetic Structure of Daphnia cucullata SARS, 1862 Native Population in Boreal Lakes
Authors: Brakovska Aija , Škute Nataļja
Published: October 2023

We have used Daphnia cucullata as a model organism for the first time in the four deepest Latvian lakes from the Boreal biogeographical region lakes in order to find the genetic diversity of Daphnia cucullata populations. During the research, the most appropriate microsatellite markers for future genetic studies of Daphnia cucullata populations in Boreal biogeographical region lakes. It was the loci Dgm105 and Dgm101, in which the maximum number of alleles and the maximum number of private alleles were found. The Dgm105 locus had five private alleles (62% of all detected alleles), while the Dgm101 locus had four private alleles (57% of all detected alleles) in these loci. We was determined the observed heterozygosity (Hobs) and the expected heterozygosity (Hexp) level (by Hardy-Weinberg), the number of polymorphic loci, the number of detected alleles in each analyzed microsatellite locus, the average number of alleles at the locus (Na), the average effective number of alleles at the locus (Ne), FST of the population genetic differentiation, the genetic distance (D) (by Nei) and significance (χ2- test) of differences between the levels of observed and expected heterozygosity.
It was shown that Daphnia cucullata populations from lakes with a low number of zooplankton taxa (Riča and Geraņimovas-Ilzas) have a higher genetic diversity compared to lakes with a high number of zooplankton taxa (Dridzis and Svente) in lakes. It was found, that Daphnia cucullata populations from lakes Dridzis and Svente have the least genetic distance and these populations form a single genetic group, as confirmed by clustering
Machine Learning for Object and Action Recognition in Augmented and Mixed Reality: A Literature Review
Authors: Chamusca Iolanda , Winkler Ingrid , Pagano Tiago , Loureiro Rafael , Santos Alex , Murari Thiago
Published: October 2023

A major challenge of augmented and mixed reality applications is identifying the context and semantics of the real environment. Studies on object and action recognition were developed based on the improvement of machine learning techniques, allowing them to be annotated and recognized. This study aims to characterize current knowledge on the use of machine learning for recognizing objects and actions in augmented and mixed reality environments, increasing context awareness. Therefore, a systematic literature review of works related to these topics was made, using the Scopus and Web of Science knowledge bases. We searched articles and conference reviews or papers published between 2018 and 2022 and selected fifteen studies to be reviewed. The results indicate that there is a great demand for using machine learning to immersive technologies in factories, engineering, entertainment, education, health, among other application domains. However, these real-time interactive systems still have challenges and limitations to be solved, involving network communication, prediction time and the creation of a model that recognize objects and actions in broad contexts. Furthermore, additional research is needed to investigate how object and action recognition can increase context awareness in augmented reality applications.
Lily Database: A Comprehensive Genomic Resource for the Liliaceae Family
Authors: Biswas Manosh Kumar , Natarajan Sathish kumar , Biswas Dhiman , Howlader Jewel , Park Jong-In , Nou Ill-Sup
Published: October 2023

Lily database online genomic resource composed of Korean Lily Germplasm Collection, Transcriptome Sequences, molecular markers, transcription factors (TF) and DEGs data. A total of ~0.23 gb of RNA-sequences data were mined for gene identification, marker development and gene expression analysis. As a result, 47,863 SSR, 20,929 SNP and 1213 COS-marker were developed. A total of 1327 TF genes were identified and characterized. This is the first unique, user-friendly, genomic resource database for Lilium species. It is a relational database based on a ‘three-tier architecture’ that catalogs all the information in MySQL table and a user-friendly query interface and data visualization page developed using JavaScript, PHP and HTML code. The search parameters are highly flexible, user can be retrieved data by using either single or multiple search parameters. Data present in this database can be used for germplasm characterization, gene discovery, population structure analysis, QTL mapping and accelerating the lily variety improvements. This database can be accessed through this link: http://www.genomicsres.org/lilidb/.
Robotizing Audit of E-invoices for Sustainable Purpose
Authors: Zheng Tian-Jun , Cheng Jia-Rong , Weng Yiao-Lin , Yang Yi-Fang , Sheu Guang-Yih
Published: October 2023

Taiwan’s Chi Mei Medical Center has a vision of becoming a sustainable organization. They found they violated the sustainable development goal (SDG) 13 (“Climate Action”) since its workflows consume excessive tangible resources and waste much operation time. To fulfill the vision, the Chi Mei Medical Center first introduced electronic invoicing. Implementing this electronic invoicing included adopting cloud E-invoice data and creating a software robot for auditing them. This study presents this software robot and its contributions. The software robot replaces an internal auditor to log into Taiwan’s E-invoice platform, download cloud E-invoice data, and detect the inconsistency between these cloud and on-premise data. Internal auditors of the Chi Mei Medical Center only needed to confirm the detection results. They welcome this software robot since it significantly reduces their work burdens. They approved more software robots for assisting other workflows. Besides, the Chi Mei Medical Center earned profits after eliminating paper invoices. This elimination helped release less carbon. This study concludes that chasing a sustainable organization is unnecessarily equivalent to the requirement of more costs. A software robot represents the last puzzle for constructing a paperless workflow since it can resolve the resistance of existing workers to a new workflow.
Hair-Reinforced Elastomer Matrix Composites: Formulation, Mechanical Testing and Advanced Microstructural Characterization
Authors: Statnik Eugene S. , Cvjetinovic Julijana , Ignatyev Semen D. , Wassouf Loujain , Salimon Alexey I. , Korsunsky Alexander M.
Published: October 2023

Epoxy matrix composites reinforced with high-performance fibers such as carbon, Kevlar, and glass, exhibit excellent specific stiffness and strength in many mechanical applications. However, these composites are disappointingly non-recyclable and are usually disposed of in landfill sites, with no realistic prospect for biodegradation in reasonable time. In contrast, moldable composites with carbonized elastomeric matrices developed in the last decades possess attractive mechanical properties in final net-shape products and can also be incinerated or recycled. Many carbon and inorganic fillers have recently been evaluated to adjust the properties of carbonized elastomeric composites. Renewable organic fillers such as human or animal hair offer an attractive fibrous material with substantial potential for reinforcing composites with elastomeric matrices. Samples of unidirectional fiber composites (with hair volume fraction up to 7 %) and quasi-isotropic short fiber composites (with hair volume fraction up to 20 %) of human hair-reinforced nitrile butadiene rubbers (HH-NBR) were produced in the peroxide-cured and carbonized states. The samples were characterized using SEM, Raman spectroscopy and photoacoustic microscopy. Mechanical tests were performed in tension using a miniature universal testing machine. The expected effect of fiber reinforcement on the overall mechanical performance has been demonstrated for both cured and carbonized composites. Considerable enhancement of the elastic modulus (up to 10 times), ultimate tensile strength (up to 3 times) and damage tolerance was achieved. The evidence of satisfactory interfacial bonding between hair and rubber was confirmed by SEM imaging of fracture surfaces. The suitability of photoacoustic microscopy was assessed for 3D reconstruction of the fiber sub-system spatial distribution and non-destructive testing.
Spatiotemporal distribution and molecular characterization of circulating dengue virus serotypes/genotypes in Senegal from 2019 to 2023
Authors: Dieng Idrissa , Talla Cheikh , Barry Mamadou Aliou , Gaye Aboubacry , Balde Diamilatou , Ndiaye Mignane , Kane Mouhamed , Sagne Samba Niang , DIAGNE Moussa Moïse , Diop Boly , Diallo Boubacar , Sall Amadou Alpha , Faye Ousmane , Sow Abdourahmane , Fall Gamou , Loucoubar Cheikh , Faye Oumar
Published: October 2023

Dengue virus is becoming a major public health threat worldwide principally in Africa. From 2016 to 2020, 23 outbreaks were reported in Africa principally in West Africa. In Senegal outbreak are reported yearly since 2017 ; data about the circulating serotypes and their spatial and temporal distribution are limited to 2017 – 2018 period. Herein we describes up to date molecular surveillance of circulating DENV serotypes in Senegal between 2019 to 2023 and their temporal and spatial distribution around the country. For this purpose collected suspected DENV infections samples were subjected to dengue detection and serotyping using RT-qPCR methods. Positive samples subjected to temporal and spatial mapping. Subset of DENV+ samples were then sequenced and subjected to phylogenetic analysis. Results show a co-circulation of three DENV serotypes with a overall predominance of DENV-3 followed by DENV-1 with scarce cases of DENV-2 from 02_2019 to 02_2022. Interestingly data shows extinct of both serotype 1 and serotype 2 and the only circulation of DENV-3 from March 2022 to July 2023. At the genotype level analysis shows that sequenced strains belong to same genotype as previously described DENV-1 belong to genotype V, DENV-2 to cosmopolitan genotype and DENV-3 to Genotype III. Interestingly newly obtained DENV 1-3 sequences cluster in different clades within genotypes. This co-circulation of strains belonging to different clades could have effect on virus epidemiology and transmission dynamic. Overall our results highlight DENV serotypes replacement by DENV-3 accompanied by wider geographic distribution in Senegalese regions. All unmentioned results highlight the importance of virus genomic surveillance and call for further fitness studies using both in vitro and in vivo model as well as in depth phylogeographic study to uncover the virus dispersal patterns across the country.