bluuebunny/crossref_metadata_2025 huggingface dataset:
Tracking Lower Urinary Tract Symptoms and Tamsulosin Side Effects Among Older Men Using a Mobile App (PERSONAL): Feasibility and Usability Study
Authors: Lee Austin W , Kenfield Stacey A , Wang Elizabeth Y , Enriquez Anthony , Oni-Orisan Akinyemi , Steinman Michael A , Sim Ida , Breyer Benjamin N , Bauer Scott R
Published: October 2021

Background

Continuous α1a-blockade is the first-line treatment for lower urinary tract symptoms (LUTS) among older men with suspected benign prostatic hyperplasia. Variable efficacy and safety for individual men necessitate a more personalized, data-driven approach to prescribing and deprescribing tamsulosin for LUTS in older men.

Objective

We aim to evaluate the feasibility and usability of the PERSONAL (Placebo–Controlled, Randomized, Patient-Selected Outcomes, N-of-1 Trials) mobile app for tracking daily LUTS severity and medication side effects among older men receiving chronic tamsulosin therapy.

Methods

We recruited patients from the University of California, San Francisco health care system to participate in a 2-week pilot study. The primary objectives were to assess recruitment feasibility, study completion rates, frequency of symptom tracking, duration of tracking sessions, and app usability rankings measured using a follow-up survey. As secondary outcomes, we evaluated whether daily symptom tracking led to changes in LUTS severity, perceptions of tamsulosin, overall quality of life, medication adherence between baseline and follow-up surveys, and perceived app utility.

Results

We enrolled 19 men within 23 days, and 100% (19/19) of the participants completed the study. Each participant selected a unique combination of symptoms to track and recorded data in the PERSONAL app, with a median daily completion rate of 79% (11/14 days). The median duration of the app session was 44 (IQR 33) seconds. On a scale of 1 (strongly disagree) to 5 (strongly agree), the participants reported that the PERSONAL app was easy to use (mean 4.3, SD 1.0), that others could learn to use it quickly (mean 4.2, SD 0.9), and that they felt confident using the app (mean 4.4, SD 0.8). LUTS severity, quality of life, and medication adherence remained unchanged after the 2-week study period. Fewer men were satisfied with tamsulosin after using the app (14/19, 74% vs 17/19, 89% at baseline), although the perceived benefit from tamsulosin remained unchanged (18/19, 95% at baseline and at follow-up). In total, 58% (11/19) of the participants agreed that the PERSONAL app could help people like them manage their urinary symptoms.

Conclusions

This pilot study demonstrated the high feasibility and usability of the PERSONAL mobile app to track patient-selected urinary symptoms and medication side effects among older men taking tamsulosin to manage LUTS. We observed that daily symptom monitoring had no adverse effects on the secondary outcomes. This proof-of-concept study establishes a framework for future mobile app studies, such as digital n-of-1 trials, to collect comprehensive individual-level data for personalized LUTS management in older men.
Intervening on Trust in Science to Reduce Belief in COVID-19 Misinformation and Increase COVID-19 Preventive Behavioral Intentions: Randomized Controlled Trial (Preprint)
Authors: Agley Jon , Xiao Yunyu , Thompson Esi E , Chen Xiwei , Golzarri-Arroyo Lilian
Published: October 2021

BACKGROUND

Trust in science meaningfully contributes to our understanding of people’s belief in misinformation and their intentions to take actions to prevent COVID-19. However, no experimental research has sought to intervene on this variable to develop a scalable response to the COVID-19 infodemic.

OBJECTIVE

Our study examined whether brief exposure to an infographic about the scientific process might increase trust in science and thereby affect belief in misinformation and intention to take preventive actions for COVID-19.

METHODS

This two-arm, parallel-group, randomized controlled trial aimed to recruit a US representative sample of 1000 adults by age, race/ethnicity, and gender using the Prolific platform. Participants were randomly assigned to view either an intervention infographic about the scientific process or a control infographic. The intervention infographic was designed through a separate pilot study. Primary outcomes were trust in science, COVID-19 narrative belief profile, and COVID-19 preventive behavioral intentions. We also collected 12 covariates and incorporated them into all analyses. All outcomes were collected using web-based assessment.

RESULTS

From January 22, 2021 to January 24, 2021, 1017 participants completed the study. The intervention slightly improved trust in science (difference-in-difference 0.03, SE 0.01, t1000=2.16, P=.031). No direct intervention effect was observed on belief profile membership, but there was some evidence of an indirect intervention effect mediated by trust in science (adjusted odds ratio 1.06, SE 0.03, 95% CI 1.00-1.12, z=2.01, P=.045) on membership in the “scientific” profile compared with the others. No direct nor indirect effects on preventive behaviors were observed.

CONCLUSIONS

Briefly viewing an infographic about science appeared to cause a small aggregate increase in trust in science, which may have, in turn, reduced the believability of COVID-19 misinformation. The effect sizes were small but commensurate with our 60-second, highly scalable intervention approach. Researchers should study the potential for truthful messaging about how science works to serve as misinformation inoculation and test how best to do so.

CLINICALTRIAL

NCT04557241; https://clinicaltrials.gov/ct2/show/NCT04557241

INTERNATIONAL REGISTERED REPORT

RR2-10.2196/24383
La huella de Freire en la educación intercultural: miradas cruzadas a la educación superior en Colombia y México
Authors: Montoya-Peláez Leonardo , Mateos Cortés Laura Selene , Dietz Gunther
Published: October 2021

Objetivo: analizar las “huellas” que ha dejado la pedagogía crítica de Paulo Freire en la educación intercultural. Tomamos como referentes empíricos dos regiones indígenas plurilingües: el Departamento del Cauca en Colombia y el Estado de Veracruz en México. Nos preguntamos qué presencia tiene la pedagogía crítica de Paulo Freire entre los protagonistas que crean la Universidad Autónoma Indígena Intercultural (UAIIN) en el Cauca colombiano, por un lado, y la Universidad Veracruzana Intercultural (UVI) en la costa del Golfo de México, por el otro.Diseño metodológico: a partir de datos empíricos construidos mediante etnografías colaborativas y ampliados mediante el análisis de documentos fundacionales de ambas instituciones, se analizan y contrastan los conceptos y métodos político-pedagógicos que la impronta que la propuesta freiriana ha dejado en los fundadores y protagonistas de las instituciones de educación superior aquí estudiadas.Resultados: se identifica un triángulo de confluencias entre 1) una educación indígena de orientación comunitaria, que es entendida por sus actores como una educación propia, 2) el legado freiriano de la educación popular, conservado y transmitida antes que nada por movimientos sociales y 3) la educación bilingüe e intercultural promovida por la academia y por actores gubernamentales.Limitaciones de la investigación: nuestra investigación se limita a dos estudios de caso.Hallazgos: se esboza cómo modelos universitarios desarrollados “desde abajo” logran proporcionar una “educación de calidad” – en el sentido de una educación inclusiva y equitativa que promueve literacidades críticas y oportunidades de empoderamiento comunitaria, todos ellos elementos contenidos en el objetivo cuatro de los Objetivos de Desarrollo Sustentable.
Effects of Aggregate Size on the Concrete Strength
Authors: Khan Tayeed Feroz
Published: October 2021

Abstract: With the advancement in the technology, there is an immense growth in the field of construction as well, of which concrete forms the basic unit. Concrete is the structural material consisting of a hard, chemically inert particulate substance, known as aggregate (usually sand and gravel), that is bonded together by cement and water. Aggregate can be fine or coarse, depending on its size. Fine and coarse aggregates make upto 65-80% of the bulk of concrete volume and reduces the cost of concrete formation (1/4 to 1/8 of the cost of cement). Keeping this thing in view, this study is done to find the size of aggregate having more strength so that a particular size of aggregate can be used to meet our demands. The aggregates used are of the size 10mm, 20mm 40mm and mixture of 10mm, 20mm and 40mm. The concrete cubes (150mm x 150mm x 150mm) prepared are tested after 7 days, 14 days and 28 days of curing. The grade of concrete used in this research is M30. Keywords: Concrete, Compressive strength, aggregates, Concrete cubes, cement, water-cement ratio, mix design, M30 grade, Compressive Testing Machine (CTM), curing
Seismic Analysis of a Residential Building Considering Different Types of Opening Arrangement in the Infill Wall
Authors: Soni Kapil Shankar
Published: October 2021

Abstract: Infill walls are inevitable components of any structure to create dispassion between interior space and external condition. In general, there are some prevalent openings inside the infill walls because of practical needs, architectural observations or aesthetic inspections. In current design practice, strength and inflexibility contribution of infill walls aren't thought of. However, the presence of infill walls may impact the seismic reaction of structures exposed to earthquake loads and cause a conduct which is not the same as that estimated for a bare frame. Additionally, partial openings inside infill walls are significant parameter prompting the seismic behaviour of infilled frames in this manner retreating lateral stiffness and strength. In this study is proposed to compare various models of buildings considering the openings (10% of surface area) at different locations in the infill walls for the seismic behaviour. A G+13 residential building is considered in Zone III with soil type II and analysis is carried out by Response Spectrum Method. Various parameters are considered such as Natural Time period, Base shear, Storey displacement, Storey drift and Storey stiffness were studied. The comparative study could simplify designers and code developers in selecting and recommending appropriate analytical models for estimating strength, stiffness, failure modes and other properties of infill frames with openings. Keywords: Residential Building, Openings Infill Wall, ETAB Software, Natural Time Period, Base Shear, Storey Shear, Storey Displacement, Storey Drift, Storey Stiffness.
Evaluation of Transformer Model for Conversational Chatbots Using Cosine Similarity Technique
Authors: Joshi Atharva
Published: October 2021

Abstract: The use of chatbots has seen a significant rise in the past few years, these pieces of software are seen on various Ecommerce platforms or banking platforms. These applications mostly involve the use of Rule-based chatbots, in this paper we have explored the possibility of using smart chatbots which can have a free-flowing conversation with the user. The training of these chatbots determines their ability to have a human-like conversation. The transformer model in this study has an encoderdecoder architecture, with a self-attention layer. The self-attention layer helps the model to have a context of the input, which gives it a reference of each word with respect to the other words in the sentence to the model. The model is being trained for various epochs and these outputs have been based against expected output and their similarity is calculated using Cosine Similarity Technique. The results from these tests were observed and presented in the paper. Keywords: Chatbot, Transformer Model, Self -Attention Layer, Epochs, Cosine Similarity.
Cross-cultural comparison of preferences for the external appearance of artificial intelligence agents
Authors: Kim Youngsang , Yoo Hoonsik
Published: October 2021

We analyzed international differences in preferences related to the two dimensional (2D) versus three dimensional (3D) and male versus female external appearance of artificial intelligence (AI) agents for use in self-driving automobiles. We recruited 823 participants in five countries
(South Korea, United States, China, Russia, and Brazil), who completed a survey. South Korean, Chinese, and North American respondents preferred a 2D appearance of the AI agent, which appears to result from the religious or philosophical views held in countries with a large or growing number
of Christians, whereas Brazilian and Russian respondents preferred a 3D appearance. Brazilian respondents' high rate of functional illiteracy may be the reason for this finding; however, there were difficulties in identifying the reason for the Russian preference. Furthermore, men in all five
countries preferred female AI agents, whereas South Korean, Chinese, and Russian women preferred female agents, but in the United States and Brazil women preferred male agents. These findings may offer valuable guidelines for design of personalized AI agent appearance, taking into account
differences in preferences between countries and by gender.
HISTORICAL SPACE IN A MODERN HISTORICAL STUDY
Authors:   Academician I.G. Petrovskii Bryansk State University (Russia), Zolotov V.I.
Published: October 2021

The paper considers some problems of learning Historical Space, which is one of the modern historical knowledge’s directions. In the mid-twentieth century, F. Brodel foregrounded matter of Historical Space social component. Understanding of different globalization’s scope, correlation between national and supranational, special features of developing different nations becomes more and more demanding in modern social, humanitarian knowledge. In methodology topic geographical space is limited by social interaction, and in certain way, transforming into historical space. Subject field of Historical Space anyway is sociocultural and defines features of social community’s existence. Boarders of community forms chains of interaction, also forms limits of real individuals’ behaviour and their interpersonal relationships. Nature of Historical Space’s subject produces the problem of correlation between sociological and anthropological approach. The importance of anthropological episteme, the profound unconscious basis of social practises, is more and more visibly in modern historical knowledge (I.M Savelieva). Lack of attention to such basis became an object of criticism Brodel’s «geohistory» and his irrecognition of history of mentalities as a subject defining main directions of social development. With specific examples, P.U. Uvarov considers the process of establishment medieval civilization in the context of epoch different social communities’ interactions. Relocation of nomadic civilizations from East and Central Asia to the West led to fundamental changes in landowner’s society in the West of Eurasia. In this area were formed circumstances, that provided effective interaction between individual and society in space of parish and manor, these two centers of power and influence, in the condition of weak government. Way of thinking in the region guaranteed creative potential of social contradictions. Spain’s loss of power and wealth by the end of XVI century was analyzed through perception of the world so-called picaro, the peninsula citizen, disrupted his entire routine, the keeper of social negative attitudes of mind and behavior, by I.U. Nikolaeva. Time and space perspectives of learning Historical Study with appropriate multidisciplinary approach gain new heuristic potential.
RURAL TEACHER SERAFIMA KILINA: RECONSTRUCTION OF THE BIOGRAPHY OF "THE DEPRIVED WOMAN" OF THE 1930S.
Authors:   Ural Federal University (Russia), Kilin A.P.
Published: October 2021

The article is devoted to the analysis of the social situation of disenfranchised citizens. The object of the study is an ordinary citizen of the USSR: a former rural teacher and the wife of a priest Serafima Aleksandrovna Kilina (born in 1888), the subject of the article is the reconstruction of her biography. The methodological basis of the research is the anthropological approach and the synthesis of macro- and micro-history. The main source of the study is the personal file of a citizen who filed a petition before the election commission to restore their electoral rights. The personal file is a complex and multi-component source, which contains documents reflecting the quasi-judicial procedure for considering the applicant's appeal, as well as necessary and sufficient materials for making a decision, received at the initiative of the applicant or members of the election commission. The source base is supplemented by legal acts regulating the deprivation and restoration of voting rights. Materials of S. A. Kilina's personal file contain significant factual data that allow us to reconstruct her biography; they describe the bureaucratic procedures figuratively and in detail; they contain fragments of direct speech of the participants of the events, which makes this historical source very valuable. S. A. Kilina's biography includes both typical and unique facts that allow us to expand our understanding of the procedure for disenfranchisement and employment practices in early Soviet society. The fate of the citizen in the transition era allows us to reflect the process of social construction of the "new person", which, contrary to the declared goals, not only provoked downward social mobility and negative social selection, but could have more tragic consequences.
Las normas NIIF como herramienta gerencial: percepciones de estudiantes universitarios de programas de administración y ciencias contables
Authors: Rueda-Vera Gerson , Luna-Pereira Henry Orlando , Avendaño-Castro William Rodrigo
Published: October 2021

El objetivo de este artículo fue mostrar las percepciones de los estudiantes universitarios de las carreras de administración y ciencias contables de una universidad pública de la ciudad de Cúcuta, Colombia, en torno a las Normas Internacionales de Información Financiera (NIIF) como herramienta gerencial. Lo anterior corresponde a un estudio enmarcado en el paradigma empírico-analítico y a un enfoque cuantitativo. La investigación cuenta con un diseño no experimental, transversal y de nivel descriptivo. La población en estudio estuvo integrada por 5000 estudiantes y la muestra por 326 individuos de tres programas académicos: contaduría pública, administración de empresas y tecnología en gestión comercial y financiera. Como instrumento se aplicó un cuestionario tipo Likert compuesto por 25 preguntas en la que se analizaron las variables aspectos socio-demográficos, conocimiento NIIF y NIIF como herramienta gerencial. Cada una de estas variables estuvo integrada por distintas dimensiones y aspectos. Los datos fueron analizados a través de procesos de estadística descriptiva. En términos generales, la mayoría de los estudiantes que participaron en el estudio percibieron que tienen un conocimiento claro y preciso en torno a las NIIF en cada uno de los ámbitos estudiados, incluyendo su potencial empleo como herramienta gerencial. Se concluye que un porcentaje significativo de estudiantes reconocen las NIIF como una herramienta en el campo gerencial que apoya la toma de decisiones, la gestión contable y financiera, el control de las operaciones de las empresas y su información financiera, los procesos de identificación y análisis de problemas operativos, tácticos y gerenciales, las adecuaciones y adaptaciones tecnológicas.
ANÁLISE INTERLINGUÍSTICA DO RÓTICOS A PARTIR DA EXPERIÊNCIA DE USO
Authors: De Mesquita Neto José Rodrigues
Published: October 2021

Este trabalho tem como objetivo geral analisar o papel da experiência de uso na construção da interfonologia dos róticos do português brasileiro e do espanhol como língua adicional. Temos como pergunta-problema: como a experiência de uso influi na construção da interfonologia dos róticos entre o PB e o ELA? Como hipótese básica, acreditamos que quanto mais o informante tenha contato com a língua estudada mais ele se distanciará das influências da sua língua materna. Para a realização da pesquisa, ancoramo-nos teoricamente nos modelos fonológicos multirepresentacionais: Fonologia de Uso (BYBBE, 2001) e Modelo de Exemplares (PIERREHUMBERT, 2001). A metodologia é de cunho quantitativo e de corte transversal, traz como corpus o áudio de 770 tokens em que os róticos aparecem em sete diferentes contextos fonotáticos e em dois experimentos. Desse modo, verificamos que a experiência de uso afeta em maior proporção alguns contextos mais que a outros e que isso reflete na construção interfonológica.
EFEITOS DA PROSÓDIA DE L2 NO ENSINO DE PRONÚNCIA E NA COMUNICAÇÃO ORAL
Authors: Silva Jr Leônidas José da , Barbosa Plínio A.
Published: October 2021

O presente trabalho tem como objetivo apresentar os efeitos e a importância do ensino de pronúncia a partir da prosódia de L2 como elemento central do desenvolvimento de habilidades relacionadas à oralidade na tentativa de minimizar desvios de pronúncia e potencializar as trocas conversacionais na comunicação oral.  Na Fundamentação teórica, nos embasamos em estudos como os de Celce-Murcia et al. (2010), Derwing e Munro (2015), Levis (2018) dentre outros, para elucidar a importância da prosódia no ensino de pronúncia e na comunicação oral em L2; Urbani (2012), Silva Jr. e Barbosa (2019, 2020) dentre outros, quando da escolha de técnicas e protocolo para extração de parâmetros acústicos duracionais e melódicos da pesquisa fonético-prosódica em L2. Na Metodologia, realizamos uma coleta de dados com falantes brasileiros de inglês/L2 e falantes americanos dos Estados Unidos de inglês/L1. Cada participante leu um texto do qual extraímos dez enunciados para análise. O tratamento acústico-prosódico foi realizado com base na duração de sílabas fonéticas (unidades VV) e com base na frequência fundamental; ambas normalizadas via Método Lobanov (z-score). Em seguida, realizamos a técnica estatística ANOVA para verificar o efeito dos grupos tanto na duração como na frequência fundamental. Os resultados apontam diferenças significativas entre os nativos e os brasileiros nos parâmetros aqui apresentados. Concluímos, ainda que de modo preliminar, que a utilização da prosódia de L2 é primordial na tentativa de potencializar o ensino de pronúncia e a comunicação oral do falante.
PERCEPÇÃO DOS PROFESSORES DO ENSINO FUNDAMENTAL I QUANTO AOS IMPACTOS DA PANDEMIA DO COVID-19 NO PROCESSO DE APRENDIZAGEM INFANTIL
Authors: Delgado Isabelle Cahino , Pontes dos Santos Pâmela , Sousa de Brito Maria Milena
Published: October 2021

Em virtude da pandemia do Coronavírus ocorrida no ano de 2020 e do isolamento social como forma de controle para o avanço da doença, as escolas precisaram ser fechadas e, assim, adotaram o ensino remoto emergencial para dar continuidade ao ano letivo. Partindo desse pressuposto, o objetivo desta pesquisa é apresentar, na percepção dos professores do Ensino Fundamental I, um panorama do processo de ensino-aprendizagem vivenciado ao longo da pandemia do COVID-19 por meio da modalidade remota. O estudo se caracteriza por ser do tipo transversal, exploratório e de caráter quali-quantitativo. Participaram 11 professoras do Ensino Fundamental I de instituições privadas de ensino. A coleta de dados ocorreu através de um questionário online divulgado previamente nas redes sociais. Nos resultados, foi observado que os professores conseguem identificar os alunos com dificuldade de aprendizagem, e que estes tinham acesso aos aparelhos eletrônicos mas não sabiam como usá-los com intuito pedagógico. Algumas escolas não ofereceram esse suporte ao docente, por meio de capacitações para o uso dos aparelhos e das novas plataformas para as transmissões das aulas, por exemplo. O papel da família neste processo foi de suma importância para uma aprendizagem eficaz das crianças. Ainda assim, foi notado mudanças comportamentais durante este período. A quarentena e o ensino remoto trouxeram impactos negativos na saúde mental dos professores que, por sua vez, não apresentam segurança quanto à eficácia do ensino remoto emergencial. Dessa forma, a presente pesquisa revelou de forma sucinta, na visão dos professores, os aspectos positivos e as fragilidades do ensino remoto emergencial e, ainda, seus impactos na aprendizagem infantil. No mais, apresentou limitações quanto ao número de participantes e espera-se que novos estudos sejam desenvolvidos com um número maior de voluntários.
[ID 56326] CICLO GRAVÍDICO-PUERPERAL: OPORTUNIDADES PARA SAÚDE (BUCAL) NA ESTRATÉGIA SAÚDE DA FAMÍLIA
Authors: De Lucena Simões Maria Isabel , De Souza Barbosa Ailma , Batista de Sousa Nétto Otacílio , Ebrahim Queiroga Verônica , Tavares de Sousa Emerson , Delano Soares Forte Franklin
Published: October 2021

Objetivo: Compreender as percepções de gestantes sobre a implementação de rodas de conversa a respeito da saúde bucal, no ciclo gravídico-puerperal, como proposta de estímulo ao debate entre as gestantes e a Equipe de Saúde da Família (eSF). Metodologia: A pesquisa-ação foi concebida em três fases: exploratória (entrevistas com gestantes), de planejamento e execução (intervenção: rodas de conversa) e de avaliação (grupo focal - GF). As entrevistas e o GF foram gravados, transcritos e interpretados pela análise temática. As entrevistas revelaram crenças e dúvidas relacionadas à gestação, ao parto e aos cuidados com os bebês recém-nascidos. A interpretação das transcrições foi realizada com base na análise de conteúdo de Bardin. As etapas da pesquisa foram orientadas pelo instrumento Quality Improvement Reporting Excellence e pelo Consolidated criteria for reporting qualitative research. Resultados: O estudo identificou que existe um claro reconhecimento da necessidade de inserir a saúde bucal nas temáticas abordadas, durante o ciclo gravídico-puerperal. As gestantes consideraram que as rodas de conversas foram potentes dispositivos, proporcionando vínculos, reflexões e aproximação entre os sujeitos envolvidos. O método apresentou potencial para o agir em favor do diálogo, para a compreensão da realidade e para as novas formas de construir práticas promotoras de saúde. Conclusão: O percurso da pesquisa-ação evidenciou a importância da construção de conteúdos e significados para as gestantes, com base na compreensão crítico-reflexiva da realidade e construção de práticas colaborativas para efetivamente promover saúde e vida nos territórios.
[ID 57089] ANÁLISE CORRELACIONAL DO DESEMPENHO FUNCIONAL E MUSCULAR DO OMBRO DE ATLETAS DE BASQUETE EM CADEIRA DE RODAS E REGULAR
Authors: Rainer Daniela Fernanda , Nathu Lodi Mayra , Saciloto Tadiello Gerson , Viçosa Bonetti Leandro
Published: October 2021

Objetivo: Analisar o desempenho funcional e muscular da articulação glenoumeral de atletas do basquete em cadeira de rodas e comparar com atletas do basquete regular. Metodologia: Oito atletas do basquete em cadeira de rodas e oito atletas do basquete regular fizeram parte da amostra. Para a análise funcional, os testes realizados foram o maximal pass e o arremesso de medicine ball. Em seguida, foi realizada a avaliação do desempenho muscular dos músculos rotadores externos e internos do ombro, utilizando dinamômetro isocinético, no modo concêntrico-concêntrico nas velocidades angulares de 60º/s., 180º/s. e 240º/s. O teste t pareado foi utilizado para a comparação entre os membros e o teste t não pareado para a comparação entre os grupos. O teste de correlação de Spearman foi utilizado para verificar as correlações entre as variáveis funcionais e musculares. Foi considerado o nível de significância de p<0,05. Resultados: Não ocorreram diferenças estatisticamente significativas entre os grupos, tanto nas variáveis funcionais quanto nas musculares; assim como não existiram diferenças entre os membros nas análises de desempenho muscular. No entanto, correlações fortes e significativas foram encontradas entre o arremesso de medicine ball e os valores médios de pico de torque dos rotadores externos e internos do ombro (p<0,05). Conclusão: As fortes correlações entre o teste do arremesso de medicine ball e os valores médios de pico de torque sugerem que este teste funcional é uma ferramenta útil e pode ser considerada para a avaliação de desempenho muscular quando não é possível a utilização da dinamometria isocinética.
[ID 57204] EFEITOS DO OCTIL-METOXICINAMATO NA HISTOPATOLOGIA DO TESTÍCULO, RIM E FÍGADO DE RATOS WISTAR
Authors: Kunes Lopes Vitor , Crisci Ana Rosa
Published: October 2021

Objetivo: Investigar os efeitos adversos que o OMC pode causar nas funções reprodutiva, hepática e renal, por meio da análise comparativa da morfologia dos testículos, rins e fígados, qualidade do esperma e alterações na massa corporal de ratos Wistar. Metodologia: Os animais, com 2 meses de idade, foram divididos em dois grupos, os quais o primeiro grupo, controle, ingeriu apenas óleo de milho, a partir de uma dose inicial de 0,6ml e o segundo grupo, tratado, ingeriu apenas o OMC, com a mesma dose inicial. As doses foram ajustadas diariamente com base no peso atual do animal, em uma proporção de 5ml/kg. Após 21 dias de exposição às substâncias, os animais foram sacrificados e foi realizada a laparotomia para coleta de testículos, rins e fígado para análise histopatológica, além de amostras de esperma para elaboração do espermograma. Resultados: A análise histopatológica evidenciou áreas hemorrágicas no parênquima do córtex renal, alterações celulares nos cordões de hepatócitos, perda dos tubos seminíferos e alterações nas células de linhagem espermatogênica. A análise do espermograma comprovou que a substância causou um aumento na taxa de espermatozoides anormais, com aumento no número de anomalias na cabeça e cauda. Conclusão: Foi constatado que o filtro solar analisado, a partir das alterações morfológicas nos órgãos e na qualidade do sêmen, de fato afetou as funções reprodutivas, hepáticas e renais dos animais analisados.
[ID 57237] A INFLUÊNCIA DO ACESSO À SAÚDE NA APRESENTAÇÃO CLÍNICA DAS NEOPLASIAS BENIGNAS E MALIGNAS DA TIREOIDE EM PACIENTES SUBMETIDOS À TIREOIDECTOMIA TOTAL
Authors: Santos Suzane Cristina , Da Silva Figueiredo Felipe Nathan , Alves Figueiredo David Livingstone
Published: October 2021

Objetivo: Avaliar a influência do acesso à saúde na apresentação clínica e histopatológica das neoplasias tireoidianas benignas e malignas em pacientes submetidos à tireoidectomia total. Metodologia: Foi realizada a revisão de prontuários de pacientes submetidos à tireoidectomia total em um serviço de cirurgia de cabeça e pescoço do município de Guarapuava, Paraná, Brasil, entre os anos de 2003 e 2017. Foram coletadas informações demográficas (idade, sexo, estado civil e tipo de acesso à saúde) e clínicas (volume total da tireoide, diagnóstico patológico, peso dos espécimes pós-cirúrgicos e estadiamento patológico e clínico). A amostra foi dividida em dois grupos, pacientes atendidos pelo SUS e saúde suplementar. Para a análise dos dados foi utilizando o software estatístico SPSS versão 20.0. O nível de significância foi p<0,05. Resultados: Dentre os 315 pacientes estudados, 104 (33,02%) foram tratados pelo SUS e 211 (66,98%) pela saúde suplementar. Nos dois grupos, o volume total da tireoide foi menor em pacientes com menos de 45 anos, nas mulheres e nas neoplasias malignas (p<0,001), enquanto, o peso do espécime cirúrgico foi menor em pacientes com menos de 45 anos, em pacientes atendidos pela saúde suplementar (p<0,001) e nas neoplasias malignas (p<0,049).  Os casos atendidos pelo SUS apresentaram maior volume total da glândula (p<0,001) e maior peso do espécime cirúrgico (p<0,001), além de maior incidência de metástases regionais (p=0,030). Conclusão: O tipo de acesso à saúde influencia na apresentação clínica das neoplasias da tireoide em relação ao volume total da tireoide, presença de metástases regionais e peso do espécime cirúrgico.
Influence of different data cleaning solutions of point-occurrence records on downstream macroecological diversity models
Authors: Fuehrding-Potschkat Petra , Kreft Holger , Ickert-Bond Stefanie
Published: October 2021

Digital point-occurrence records from the Global Biodiversity
Information Facility (GBIF) and other repositories enable a wide range
of research in macroecology and biogeography. However, data errors may
hamper immediate use. Manual data cleaning is time-consuming and often
unfeasible, given that the databases may contain thousands or millions
of records. Automated data cleaning pipelines are therefore of high
importance. This study examined the extent to which cleaned data from
six pipelines using data cleaning tools (e.g., the GBIF web application,
different R packages) affect downstream species distribution models. In
addition, we assessed how the pipeline data differ from expert data.
From 13,889 North American Ephedra observations in GBIF, the pipelines
removed 31.7% to 62.7% false-positives, invalid coordinates, and
duplicates, leading to data sets that included between 9,484 (GBIF
application) and 5,196 records (manual-guided filtering). The expert
data consisted of 703 thoroughly handpicked records, comparable to data
from field studies. Although differences in the record numbers were
relatively large, stacked species distribution models (sSDM) from the
pipelines and the expert data were strongly related (mean Pearson’s r
across the pipelines: 0.9986, versus the expert data: 0.9173). The
ever-stronger correlations resulted from occurrence information that
became increasingly condensed in the course of the workflow (from
individual occurrences to collectivized occurrences in grid cells to
predicted probabilities in the sSDMs). In sum, our results suggest that
the R package-based pipelines reliably identified invalid coordinates.
In contrast, the GBIF-filtered data still contained both spatial and
taxonomic errors. However, major drawbacks emerge from the fact that no
pipeline fully discovered misidentified specimens without the assistance
of expert taxonomic knowledge. We conclude that application-filtered
GBIF data will still need additional review to achieve higher spatial
data quality. Achieving high-quality taxonomic data will require extra
effort, probably by thoroughly analyzing the data for misidentified
taxa, supported by experts.
Prevalence and course of fear of childbirth during pregnancy and need for help in nulliparous women, HEAR study: a cohort study
Authors: Hendrix Yvette , Baas Melanie , Vanhommerig Joost , Jongh Ad De , Pampus Maria van
Published: October 2021

Objective To determine the prevalence and course of fear of
childbirth (FoC) according to gestational age and to identify risk
factors for FoC, the influence of FoC on preferred mode of delivery and
self-reported need for help. Study Design Cross-sectional and
cohort study Setting Urban hospital, midwifery practices,
social media, maternity websites. Population Nulliparous
pregnant women May 2020-January 2021. Methods Participants
completed an online survey. Women who completed the survey in the first
or second trimester(T0) were approached again in their third
trimester(T1). Questionnaires indexing FoC, social support, anxiety,
depressive symptoms, self-reported need for help, and preferred mode of
delivery were included. Main outcome measures Fear of
childbirth, defined as W-DEQ A score ≥ 85 Results In total, 364
women were enrolled at T0, and 118 women were included in the
longitudinal analysis. Cross-sectional analysis showed a prevalence of
FoC of 18.4% with no significant difference between trimesters. In the
longitudinal sample, prevalence of FoC decreased from 18.6%(T0) to
11.0%(T1), P=0.004. W-DEQ A mean scores decreased significantly,
P<0.001, although 41 (34.7%) women showed an increase
in scores. FoC was associated with elevated anxiety, less family
support, prenatal care of the obstetrician by choice, preference for a
cesarean section, and for pain relief. Women with FoC were more likely
to actively seek for help compared to women without FoC.
Conclusions While FoC is common, prevalence decreases over the
course of pregnancy. Because women with FoC are actively seeking for
help, this problem should be addressed better, and help should be
offered.
Hydatid cyst of the liver with portal thrombosis: A case report
Authors: Milani Nasrin , Majidi Najme , Goshayeshi Laden
Published: October 2021

The extensive involvement of the liver due to hydatid cyst and it’s
invasion to the portal vein and resulted portal vein thrombosis are rare
complications of hydatid cyst. The diagnosis and treatment of hydatid
liver cyst and its rare complication such as thrombosis in infected
patients should be critically considered.
Genetic Variation in Photosynthetic Responses to Chilling Modulates Proton Motive Force, Cyclic Electron Flow and Photosystem II Photoinhibition
Authors: Hoh Donghee , Osei-Bonsu Isaac , Chattopadhyay Abhijnan , Kanazawa Atsuko , Fisher Nicholas , Tessmer Oliver , Cruz Jeffrey , Roberts Philip , Huynh Bao Lam , Hall David , Kramer David M.
Published: October 2021

The work demonstrates the use of detailed, high-throughput phenotyping
to generate and test mechanistic models to explain the genetic diversity
of photosynthetic responses to abiotic stress. We assessed a population
of recombinant inbred lines (RILs) of cowpea (Vigna unguiculata. (L.)
Walp.) with significant differences in a range of photosynthetic
responses to chilling. We found well-defined, colocalized (overlapping)
QTL intervals for photosynthetic parameters, suggesting linkages among
the redox states of Q, the thylakoid pmf,
through effects on cyclic electron flow and photodamage to PSII. We
propose that these genetic variations optimize photosynthesis in the
tolerant lines under low temperatures, preventing recombination
reactions within Photosystem II that can lead to deleterious
O production. By contrast, we did
not observe linkages to PSI redox state, PSI photodamage or ATP synthase
activity, or nyctinastic (diurnally controlled) leaf movements, likely
indicating that several proposed models likely do not contribute to the
genetic control of photosynthesis at low temperature in our mapping
panel. The identified QTL intervals include a range of potential
causative genetic components, with direct applications to breeding of
photosynthesis for more climate-resilient productivity.
The necessity of Integrated Medicine to treat SARS-Cov-2/ COVID-19 patient: A case report
Authors: Tiwari Sagun , Tiwari Sujan , Sapkota Namrata , Sapkota Bhanu
Published: October 2021

Psychological and psychosocial issues are more prominent issues of an
individual in any disease, which could further deteriorate patients’
condition and hamper their quality of life. However, in treating
SARS-CoV-2/COVID-19, those patients’ mental, social, and emotional
aspects are still overlooked.
Treatment of refractory thrombotic thrombocytopenic purpura with Caplacizumab : A case report
Authors: maat zakaria , awad lana , Habib Mhd Baraa , Zafar. Abdul Aziz , albattah afaf
Published: October 2021

Caplacizumab can be used as a treatment for TTP refractory to
plasmapheresis and steroid
Image annotating tools for agricultural purpose - A requirements study
Authors: Bator Marcin , Pankiewicz Maciej
Published: October 2021

Images of natural scenes, like those relevant for agriculture, are characterised with a variety of forms of objects of interest and similarities between objects that one might want to discriminate. This introduces uncertainty to the analysis of such images. Requirements for an image annotation tool to be used in pattern recognition design for agriculture were discussed. A selection of open source annotating tools were presented. Advices how to use the software to handle uncertainty and missing functionalities were described.
The neutrality of taxation of investment projects in Serbia
Authors: Lukovic Stevan , Vrzina Stefan , Grbic Milka , Pjanic Milos
Published: October 2021

The paper analyses the neutrality of taxation of investment projects on the
example of Serbia. The aim of the research is to confirm/reject the
existence of uniformity of the tax burden on investment projects that differ
regarding the asset type, industry and the source of finance. The uniformity
of tax burden, that is, the absence of discrimination and distortive effects
of taxation, may be considered a confirmation of the tax neutrality. To
investigate neutrality of taxation the analysis employed King-Fullerton
framework of calculating effective marginal tax rates. The research results
show that the tax treatment of investment projects in Serbia is
nondiscriminatory. Marginal effective tax rates for different types of
investment projects do not vary widely; that is, there are no investment
projects that have a markedly favourable (unfavourable) tax treatment
compared to the other types of investment projects.
Caracterización de la prestación de servicios de radioterapia para el tratamiento del cáncer de próstata en Colombia
Authors: Garcés Andrés , Flórez Camilo , González Garvín , Muñoz Jorge
Published: October 2021

Se realizó un estudio bajo enfoque cuantitativo para describir aspectos técnicos y tecnológicos de las opciones de tratamiento con radioterapia (teleterapia y braquiterapia) para pacientes con cáncer de próstata órgano confinado en cualquier etapa de la enfermedad, atendidos en alguna de las 18 IPS-ESE participantes en el estudio en diferentes regiones del país. De las 18 instituciones participantes, 15 cuentan con habilitación vigente y tan sólo 3 lograron la acreditación de alta calidad en salud. No existe un protocolo unificado para el tratamiento del cáncer de próstata con radioterapia en el país y existe una gran brecha tecnológica entre los servicios de grandes y pequeñas ciudades del país. La prevalencia de cáncer reportada en el semestre de recolección de la información (julio-noviembre 2016), se encuentra en concordancia con las proyecciones de casos totales de diagnósticos de cáncer de próstata realizadas a nivel nacional.
Mindfulness como herramienta para fortalecer habilidades blandas en los ambientes de formación
Authors: Bustamante Ortiz Luis Arturo
Published: October 2021

El presente documento tiene como finalidad adelantar revisión sobre la relación del Mindfulness con la educación, en especial la capacidad de esta herramienta para fortalecer las habilidades blandas, postulándose como una posible estrategia en el marco del proceso de Retención del Servicio Nacional de Aprendizaje SENA. Metodología: se realizo la búsqueda en la literatura contó con veinticuatro referencias de estudios nacionales e internacionales del Mindfulness y su relación con las dinámicas educativas y el impacto en las habilidades blandas. Conclusiones: Se examinó el concepto de habilidades blandas en cuatro estudios encontrando que están sociadas al éxito y beneficio en la vida laboral e interpersonal, en cuanto al Mindfulness se abordó en quince documentos y finalmente en dieciocho documentos de educación relacionados con Mindfulness o habilidades blandas. El Mindfulness se muestra como una herramienta prometedora en el fortalecimiento de habilidades blandas disminuyendo la deserción escolar.
De la cuarta revolución industrial a la imagenología médica
Authors: Alviar Ferro Rodrigo , Alviar Martínez Ananda
Published: October 2021

En este texto reflexivo se hace una breve exploración de algunos alcances de la cuarta revolución industrial en el campo de la salud, mientras se exploran las implicaciones particulares de esta en los servicios de diagnóstico médico en imagenología. También se plantea un caso hipotético en el que un paciente masculino de 70 años sufre un ECV. A partir de esto, se muestran tres escenarios distintos: pasado, presente y futuro, en los que el paciente es atendido, y cuáles son los alcances de los avances tecnológicos del momento en su recuperación.
Materiał kostny z czterech grobów kultury strzyżowskiej wyeksplorowanych w latach 2015-2016 na stanowisku 15 w Rogalinie w świetle badań interdyscyplinarnych
Authors: Lorkiewicz-Muszyńska Dorota , Abreu-Głowacka Monica , Kociemba Wojciech , Glapiński Mariusz , Michalak Eliza , Ciesielka Marzanna , Hyrchała Anna
Published: October 2021

In 2008 a burial site was discovered in Rogalin (eastern Poland). Interdisciplinary investigations were carried out and it was concluded that the site was a unique example of Strzyżów culture, an agricultural culture found in eastern Poland and western Ukraine, dated to the Early Bronze Age (2000/1950–1600 BC ). Strzyżów culture spread over the area from the eastern part of Lublin Upland (area between the upper Wieprz river and Bug river) to the area of south-western Volhynia crossing Horyn river in present-day Ukraine. The highest density of its sites is in the territory of Horodło Plateau and near the town of Hrubieszów. Sixteen graves were discovered between 2009 and 2016. The aim of the study was to conduct analysis of skeletal remains from four burial graves – no. 13, 14, 15, and 16 excavated in 2015 and 2016. Research was based on macroscopic, stereomicroscopic analysis, X-ray and CT examinations.
Problem chronologii zolnika z grodziska w Chotyńcu i tworzących go poziomów użytkowych w świetle badań nad klasyfikacją i datowaniem szpil
Authors: Adamik-Proksa Joanna , Ocadryga-Tokarczyk Ewelina
Published: October 2021

The article presents the partial results of archaeological research carried out on the burgwall zolnik in Chotyniec, site 1. It aims to classify the historical objects discovered in terms of functional qualification – namely, the pins that were found in 2017-2019, and to introduce them into the scientific circulation. This interesting and relatively numerous series of artifacts complements and enriches our knowledge on many aspects of the zolnik’s function, including its chronology and cultural connections. In this sketch, an analysis of the typological and chronological position of the pins was carried out, and on its basis an attempt was made to estimate the dating of the zolnik (the usable levels that form it).
Potential study of Dillenia serrata Thunb. fruit extract from Bali Botanical Garden’s collection
Authors: Wibawa I Putu Agus Hendra , Lugrayasa I Nyoman , Sutomo Sutomo
Published: October 2021

Dillenia serrata Thunb.is a member of the Dillenia clan which is endemic to Sulawesi. D. serrata fruit is a seasonal fruit and can be used as a cooking ingredient as a sour taste, raw material for several food products such as candied fruit and syrup, and has the potential to be processed into chips and jam. Traditionally, the leaves and bark of D. serrata are also used by the local community as a sprue medicine, fever, wound medicine, treating swelling or inflammation and treating vomiting of blood. It is believed that there are still many untapped benefits from this plant. This study was conducted to determine the effectiveness of D. serrata fruit extract as an antimicrobial that causes disease in humans, and to determine its effectiveness as an antioxidant. The antioxidant test was carried out using the DPPH method while the antimicrobial test was carried out by the agar diffusion method (Kirby-Bauer). The ripe Dillenia fruit was extracted using methanol, the extract was then diluted in various concentrations for the DPPH test The results showed that the D. serrata extract had the ability as an antioxidant. The antioxidant activity of fresh fruit extracts was higher than that of dried fruit extracts. D. serrata extract is effective in inhibiting the growth of Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus mutans bacteria.