bluuebunny/crossref_metadata_2025 huggingface dataset:
Avaliação da relação entre linfócitos infiltrantes e resposta inflamatória no câncer de mama: Uma revisão sistemática
Authors: Gomes Jacqueline Moraes , Esper Ester Araújo , Ribeiro Andrea Alves
Published: December 2023

O câncer de mama é o tipo de câncer mais incidente em mulheres no mundo e atrasos em seu diagnóstico e tratamento reduzem potencialmente as taxas de sobrevida. Trata-se de uma doença heterogênea e rica em células imunes estromais, inflamatórias e fatores solúveis em seu microambiente tumoral. Os linfócitos infiltrantes de tumor (TILs) são componentes desse microambiente inflamatório e a densidade de TILs mostrou ser uma ferramenta importante na mediação da eficácia das terapias imunomoduladoras e no prognóstico de doença residual após o tratamento quimioterápico neoadjuvante. O objetivo deste estudo foi avaliar a relação entre linfócitos infiltrantes e a resposta inflamatória em mulheres com câncer de mama. Trata-se de um estudo descritivo, qualitativo, do tipo revisão sistemática de literatura. As bases de dados usadas para a pesquisa de artigos foram Pubmed, Scielo e Cochrane, com o uso dos descritores “infiltrating lymphocytes, inflammatory response e breast cancer”, e o operador booleano “And”. Foram incluídos artigos completos publicados no período de 2012 a 2022 nos idiomas inglês, português e espanhol. A revisão foi realizada de acordo com a recomendação PRISMA (Principais Itens para Relatar Revisões Sistemáticas e Meta-análise) e ferramenta Joana Briggs Institute (JBI) Appraisal Tools para avaliar o risco de viés dos estudos selecionados. Do total de 91 artigos encontrados, 17 foram selecionados para fazer parte desta revisão. Os estudos revisados revelam forte correlação entre linfócitos infiltrantes do tumor estromal (TILs) e resposta imune tumoral, podendo se tornar uma importante medida de detecção do prognóstico e da sobrevida da doença.
Tuberculose extrapulmonar com envolvimento renal e intestinal: Um desafio no diagnóstico precoce
Authors: Araújo Felipe Gabriel Andrade de , Saotome Lyu , Pierini Jéssica Louise de Godoi , Ruivo Gilson Fernandes
Published: December 2023

A tuberculose extrapulmonar é uma manifestação da doença pulmonar que afeta outros órgãos e sistemas além dos pulmões. Sua incidência tem aumentado, principalmente em pacientes com imunossupressão. O diagnóstico e tratamento dessa forma da doença são desafios clínicos devido à diversidade de órgãos afetados. Os sintomas variam de acordo com o local afetado e o diagnóstico preciso requer uma abordagem multidisciplinar. O Brasil possui alta carga de tuberculose e a forma extrapulmonar corresponde a cerca de 20% dos casos notificados. Este estudo tem como propósito apresentar um relato de caso recente de tuberculose extrapulmonar com acometimento renal e intestinal, analisando os indícios e sintomas manifestados pela paciente, as abordagens diagnósticas empregadas e o tratamento instituído com base nas evidências científicas mais atualizadas. Utilizou-se uma metodologia de relato de caso clínico com características qualitativas descritivas, realizado no Hospital localizado no município de Taubaté/SP. A paciente recebeu o tratamento adequado e obteve uma evolução clínico-laboratorial satisfatória, resultando em uma recuperação funcional. Atualmente, a paciente continua em acompanhamento no Hospital Municipal Universitário de Taubaté, sob os cuidados da equipe de Nefrologia e Hepatologia.
Explorando os benefícios terapêuticos da equoterapia no tratamento da paralisia cerebral: Um estudo de revisão
Authors: Mota Jeyelle Dias , Soares Mateus Ferreira , Riselo Juliany Reichembach
Published: December 2023

A paralisia cerebral, uma condição neuromotora resultante de danos ou desenvolvimento anormal do cérebro na infância, impacta diretamente as habilidades motoras e frequentemente afeta aspectos emocionais e sociais. O objetivo deste estudo é explorar abrangentemente os diversos aspectos da paralisia cerebral e avaliar a eficácia da equoterapia como uma intervenção terapêutica promissora. Utilizando uma metodologia de Revisão Integrativa da literatura, a pesquisa buscou evidências sobre a eficácia da equoterapia no tratamento da paralisia cerebral. Os resultados indicam que intervenções terapêuticas, como equoterapia, brincar, tratamento intensivo com suporte de peso corporal, protocolo PediaSuit e realidade virtual, apresentam impactos positivos na vida de crianças e adolescentes com paralisia cerebral. As considerações finais destacam consistentemente os benefícios significativos da equoterapia no tratamento, evidenciando melhorias não apenas nas alterações funcionais, mas também nos aspectos sociais e emocionais dos pacientes.
Toxina botulínica na disfunção temporomandibular
Authors: Gonçalves Graziela , Suguihara Roberto Teruo , Muknicka Daniella Pilon
Published: December 2023

Os desafios diários podem desencadear perturbações nos domínios ambiental, psicológico, biológico e cognitivo, impactando a homeostase sistêmica e contribuindo para o surgimento de distúrbios, como depressão e ansiedade. Pacientes expostos a tais desafios apresentam uma maior incidência de distúrbios relacionados à articulação temporomandibular (ATM). A prevalência da disfunção temporomandibular (DTM) tornou-se reconhecida, com mais de 100 milhões de casos nos anos 1990, resultando na produção anual de 3 milhões de placas oclusais nos EUA. Abordagens alternativas foram desenvolvidas, oferecendo taxas de recuperação comparáveis. Sintomas associados às DTMs incluem cefaleia, otalgia, odontalgia, dor facial e zumbido, frequentemente ligados a estresse psicológico. O sucesso terapêutico na ATM está ligado a um plano abrangente, envolvendo abordagens clínicas e cirúrgicas. A toxina botulínica (TxB) apresenta sete formas, inibindo a liberação de acetilcolina e induzindo temporária inatividade muscular. Os tipos A (TxB-A) e B (TxB-B) são aplicados clinicamente em áreas específicas. A TxBo, tipo A, é eficaz no controle da hiperatividade muscular, especialmente quando a origem da dor nas DTMs é miogênica. Essa revisão busca explorar essas interações para fornecer uma visão abrangente sobre o manejo terapêutico das DTMs.
Perfil antropométrico e percepção da qualidade de vida de mulheres acometidas com câncer de mama após tratamento quimioterápico
Authors: Dalpupo Ana Paula da Silveira , Werner Marina
Published: December 2023

O câncer de mama é a forma mais comum de neoplasia que afeta mulheres em todo o mundo, representando um desafio significativo para a saúde pública. Diversos tipos de tratamentos estão disponíveis para combater essa doença, com ênfase no tratamento sistêmico, incluindo a hormonioterapia e a quimioterapia. No entanto, esses tratamentos frequentemente acarretam efeitos colaterais que impactam o apetite e levam ao ganho de peso. Por isso, o objetivo este estudo se concentrou em analisar como as mulheres diagnosticadas com câncer de mama percebem sua qualidade de vida e como seu perfil antropométrico é afetado após concluírem o tratamento quimioterápico. Para essa investigação, adotamos uma abordagem descritiva e analítica, combinando elementos qualitativos e quantitativos. Dois questionários foram administrados às participantes: o questionário QLQ-BR23 do European Organization for Research and Treatment of Cancer (EORTC) e outro elaborado especificamente pelas pesquisadoras para avaliar a percepção das participantes sobre a qualidade de vida. Os resultados revelaram que a maioria das participantes apresentava sobrepeso de acordo com a avaliação antropométrica. Além disso, muitas relataram sintomas como fadiga, falta de ânimo e ansiedade. No questionário QLQ-BR23, notou-se que a imagem corporal foi um dos principais pontos de preocupação no quesito de escala funcional, enquanto os sintomas sistêmicos receberam mais queixas na categoria de sintomas. Esses achados sugerem que o tratamento quimioterápico tem um impacto duradouro na qualidade de vida das pacientes após sua conclusão, destacando a necessidade de investigações adicionais sobre o assunto.
Extração de DNA de cebola (Allium cepa): Perspectiva das práticas científicas por meio da prática de laboratório
Authors: Siqueira Edmilson Clarindo de , Doboszewski Bogdan
Published: December 2023

O DNA representa a unidade estrutural da vida, sendo uma das substâncias orgânicas mais conhecidas. A extração de DNA tornou-se uma alternativa ao ensino-aprendizagem nas aulas de Biologia. Neste sentido, o objetivo deste trabalho foi facilitar a aprendizagem dos alunos da disciplina de Biologia do Ensino Médio, a partir de uma atividade experimental envolvendo a extração de DNA de cebola (Allium cepa). A atividade foi implementada no laboratório de aulas práticas do IFPE-Campus Barreiros em dois momentos pedagógicos. O primeiro momento, consistiu em uma aula prática para a extração do DNA de A. cepa, usando materiais do cotidiano. No segundo momento, os estudantes foram convidados a avaliar a atividade através de um questionário. A partir da análise dos resultados, foi possível verificar que a atividade proposta incentivou a motivação, despertou à curiosidade e facilitou à aprendizagem dos educandos. Além disso, a avaliação da atividade pelos discentes foi considerada estimuladora pelos autores. Por fim, além de unir a teoria com a prática, este trabalho pode ser útil como um material de consulta sobre a molécula do DNA.
The use of extracorporeal membrane oxygenation (ECMO) for critically-ill COVID-19 patient in clinical setting: A literature review
Authors: Purnamasidhi Cokorda Agung Wahyu , Suteja Richard Christian , Utama I Made Susila , Somia I Ketut Agus , Merati Ketut Tuti Parwati , Aryabiantara I Wayan
Published: December 2023

The use of ECMO may help sustain extracorporeal life support in cases where regular less-invasive modalities failed to adequately assist the body in maintaining basic life mechanisms. Typically, VV-ECMO is used in life-threatening respiratory failure. However, experts must consider relative contraindications, answering the question: ‘Will the patient really benefit from this treatment, or will it only add emotional and economic burden, also exposing the patient to various risks of complications?’. The physiology of oxygenation within the lungs, tissues, and ECMO machine, is a modification of the basic principles of respiratory physiology. In typical VV-ECMO cannula insertion, drainage cannula is inserted via the right femoral vein percutaneously and is guided upwards through inferior vena cava with its tip 10 cm below cavoatrial junction while the reinjection cannula will be inserted through the intrajugular vein. This places the artificial lungs in series with the normal lungs rather than in a parallel form. The artificially-oxygenated blood was then returned and mixed with the native venous blood. It is important to measure maximum drainage flow to prevent shunting of the veins by setting the ECMO to the highest flow. Frequent complications include co-infection up to sepsis and coagulopathy up to complications following it. Therefore, it is always beneficial to acquire multidisciplinary judgement, particularly with hematologists, intensivists, and infectious disease specialists prior, during, and post-ECMO use.
Utilização de plantas medicinais para Covid-19 pela população suburbana de Uberaba - MG: Perfil sociodemográfico dos usuários
Authors: Carvalho Gabriel Roel Elias , Tosta Larissa Martins , Vicentine Karina Ferrazzoli Devienne , Acrani Simone
Published: December 2023

As plantas medicinais e a fitoterapia são terapêuticas usualmente utilizadas para promover bem-estar em saúde. Dentre as populações usuárias dessa prática de saúde, destacam-se moradores de baixa renda de áreas suburbanas, por se tratar de uma estratégia que envolve não só fundamentos científicos, mas também de outros determinantes como relacionamentos interpessoais, cultura, ambiente, crenças e contexto socioeconômico. Considerando o cenário pandêmico da Covid-19, o qual caracteriza-se fortemente pela constante atualização dos conhecimentos, a medicina popular tornou-se uma alternativa cientificamente respaldada e válida no processo de atenuação e/ou cura dos sintomas da infecção pelo SARS-CoV-2. Dessa forma, o presente estudo objetiva demonstrar a relação do perfil sociodemográfico da população suburbana com o uso terapêutico das plantas medicinais e fitoterápicos no tratamento sintomatológico da Covid-19, através de uma pesquisa descritiva exploratória, com abordagem qualitativa, mediante aplicação de uma entrevista semiestruturada. O presente estudo identificou o seguinte perfil de consumidores de plantas medicinais: 100% mulheres, com média de idade de 48 anos, 50% com ensino fundamental completo e residentes na região semi-periférica; evidenciando a relação desse perfil populacional com a prática terapêutica voltada à Covid-19.
Mapas conceituais como instrumento didático e avaliativo na formação docente para alunos de Física
Authors: Campos Laélia
Published: December 2023

A utilização de mapas conceituais como ferramenta auxiliar no ensino de diversas disciplinas tem crescido significativamente, tanto no âmbito da educação básica quanto nos cursos universitários de graduação e pós-graduação. Esses mapas têm a finalidade de representar relações significativas entre conceitos por meio de proposições, proporcionando um recurso esquemático que abrange um conjunto de significados conceituais inseridos na estrutura dessas proposições. No contexto educacional, os mapas conceituais desempenham um papel multifuncional. Como instrumentos didáticos, são capazes de elucidar as relações hierárquicas entre os conceitos abordados em uma aula, unidade de estudo ou curso completo. Além disso, funcionam como valiosos recursos para facilitar a compreensão e memorização, tornando o processo de aprendizado mais acessível e eficaz. Como método avaliativo, os mapas conceituais assumem um papel crucial ao ajudar na identificação de evidências de aprendizagem por parte dos alunos em relação aos conceitos de um determinado tema. Ao analisar a qualidade e a complexidade dos mapas elaborados pelos estudantes, é possível avaliar não apenas o conhecimento adquirido, mas também a capacidade de relacionar e organizar informações de forma coerente. Neste contexto, o presente trabalho visa apresentar o mapa conceitual como uma ferramenta didática fundamental no contexto de um curso de graduação em física licenciatura. Dado o caráter qualitativo e quantitativo deste estudo, este trabalho busca explorar o potencial do mapa como uma ferramenta de avaliação de conteúdo. Pretende-se assim contribuir para uma abordagem mais abrangente e eficiente no processo de ensino e aprendizagem.
Avaliação epidemiológica de vírus relacionados a infecções respiratórias agudas em um campus universitário por meio da técnica de LAMP
Authors: Bretz Gabriel Pissolati Mattos , Carobim Natalia Virtude , Fernandes Adriano Basques , Sabino Adriano de Paula , Soardi Fernanda Caroline , Gomes Karina Braga
Published: December 2023

Objetivo: Investigação epidemiológica do SARS-CoV-2, Influenza A (IAV) e Influenza B (IBV) na comunidade atendida pelo programa MonitoraCOVID da Universidade Federal de Minas Gerais (UFMG) em 2022, por meio da padronização e validação da técnica de LAMP. Métodos: Foram utilizadas amostras de swab nasofaríngeo nas reações de LAMP, realizadas simultaneamente nas mesmas condições com leitura visual. Para investigação epidemiológica, foram testados 10% do quantitativo mensal atendido pelo MonitoraCOVID. Resultados: As reações de LAMP demonstraram sensibilidade de 84,0% e 85,2% para o SARS-CoV-2 e IAV respectivamente. A prevalência de IBV foi baixa para análise dos parâmetros analíticos. A especificidade obtida foi de 100% nas três reações. A taxa anual de positividade encontrada foi: SARS-CoV-2 - 28,7%, IAV - 1,6%, IBV - 0,0%. Foram encontrados resultados indeterminados para SARS-CoV-2 e IAV (0,8% cada). Conclusão: O ensaio de LAMP foi capaz de avaliar a epidemiologia dos vírus respiratórios, podendo ser aplicado no diagnóstico em outras populações.
Problem Analysis in Sub-Assembly Department Using Empathize Design Thinking and Failure Mode Effects Analysis: A Case Study of PT X
Authors: Septa Fernando , Putrianto Novenda Kartika
Published: December 2023

PT X is a company that engages in the production of large vehicles, particularly buses. The company currently has a sub-assembly department responsible for providing support materials used in the production process. Within the sub-assembly department, there are several constraints that affect the ongoing production process. These hindrances can lead to various losses for the company. Therefore, a study is being conducted to identify and understand the obstacles present in the sub-assembly department. The problem identification process employs the empathize stage of design thinking, aiming to determine the importance of each problem. To achieve this, a ranking system known as Failure Mode Effects and Analysis is being utilized. The results indicate the existence of six problems within the sub-assembly department. Following the prioritization process, it was determined that the primary issue revolves around inadequate administrative procedures. Based on these findings, an evaluation is planned for the company, specifically focusing on the sub-assembly department. The objective is to promptly address these problems and prevent any significant impacts on the company. This abstract emphasizes the importance of identifying departmental issues and prioritizing immediate solutions.
Penerapan Metode Fault Tree Analysis Untuk Mencegah Kegagalan Pada Departemen Interior di PT X
Authors: Yolanda Metta , Ekawati Yurida , Noya Sunday
Published: December 2023

The Interior Department is one of the departments of PT X that produces bus and minibus interior parts. During the interior production process there are still quite a lot of defective products. There are six types of defects, namely air bubbles, not 100% printed, double tip insulation does not stick, torn, too dense/less dense, and color striped. The main focus of this research is to analyze the causes of failure of a process and make recommendations for improvements that can be made using the Fault Tree Analysis (FTA) method. From the FTA, improvements are needed to reduce defects in the Interior Department. Recommendations for improvement that can be given to the company are to create a checklist form to make it easier for operators to clean the mattress regularly, to check that the non-stick liquid has been sprayed twice, to ensure that the mattress has been heated every morning, to ensure that the paint has been shaken before use so that there are no striped colors, and to ensure that the paint has been sprayed twice. Then the next improvement recommendations are to provide and attach a standard description to each injection number on each product, make a machine maintenance schedule, replace the non-stick liquid with an old model that is not too strong, provide a timer on the mattress that is used as a reminder when waiting for the paint to dry, procure a mattress equipped with a sound sensor, and procure a generator.
ACCOUNTING’S STUDENTS SOFT SKILLS DEVELOPMENT IN INDUSTRIAL REVOLUTION 4.0 (CASE STUDY AT UNIVERSITIES IN BENGKULU)
Authors:   University of Bengkulu, Marietza Fenny , Oswandi Joshuwah ,   University of Bengkulu
Published: December 2023

Job competition in the era of the industrial revolution 4.0 requires accountants to have more skills in addition to the knowledge gained in college; these skills are called soft skills. However, the reality is that many accountants still lack master soft skills. This problem cannot be separated from the role of universities as providers of accounting graduates. This study aims to describe the role of universities, especially accounting study programs, in developing the soft skills of accounting students in the era of the industrial revolution 4.0. This research is qualitative research with a case study approach. The informants in this study were four managers of accounting departments, four managers of accounting student organizations, and one manager of MBKM centers working in 4 universities in Bengkulu City. The data used in this study was obtained through direct interviews with data analysis techniques in data collection, data reduction, data presentation, and conclusions. The results of this study show that Bengkulu City College has developed the soft skills of accounting students through soft skills courses, integrating soft skills development into learning, encouraging accounting students to participate in MBKM programs, organizational activities, seminars, FMD, training, and soft skills competency tests. This research helps the manager of the Bengkulu City accounting study program understand and re-evaluate the current state of soft skills development of accounting students so that it can be better in the future.
О работе сталежелезобетонных конструкций при внецентренном сжатии
Authors: КОНИН Денис Владимирович , КРЫЛОВ Алексей Сергеевич , ГАВРИЛОВ Дмитрий Николаевич , ЖДАНОВА Анастасия Андреевна , ВОРОПАЕВА Мария Игоревна
Published: December 2023

Рассмотрены вопросы работы сталежелезобетонных колонн при внецентренном сжатии. Дано обоснование выбранной темы исследования на основе анализа современной нормативной документации. Выполнен обзор литературы, отмечены особенности развития вопроса и вклад различных ученых и специалистов в совершенствование теории расчета конструкций. Приведены особенности современной нормативной методики расчета сталежелезобетонных конструкций на внецентренное сжатие, а также расчетные коэффициенты, отмечена необходимость их корректировки. Представлено подробное описание исследуемых экспериментальных конструкций и использованных материалов. Показаны последовательность испытания образцов и испытательное оборудование. Выполнены аналитические и численные расчеты колонн на внецентренное сжатие. Представлено описание расчетного комплекса и моделей материалов, численных моделей, а также особенности их построения и расчета. В результате проведенных расчетов установлен характер распределения напряжений, деформаций и особенности трещинообразования. На основании анализа экспериментальных данных, их сравнения с аналитическими и численными расчетами даны предложения по использованию полученных результатов для совершенствования нормативной базы.
Проектное управление: инжиниринг и реинжиниринг в строительстве
Authors: СБОРЩИКОВ Сергей Борисович , ЖУРАВЛЕВ Павел Анатольевич , ЛАЗАРЕВА Наталья Валериевна
Published: December 2023

В настоящее время в строительстве широко применяется проектное управление, однако вопросы, относящиеся к его нормативной регламентации и терминологической идентификации, до сих пор не решены. Рассмотрена целесообразность создания национального нормативно-методического документа по управлению проектами в строительстве, который бы закреплял специфические особенности отрасли и определял перспективные направления в организации и управлении (инжиниринг, реинжиниринг, контроллинг, логистика). Требования данного документа должны распространяться на управление строительными проектами, а также на их реализацию внутри хозяйствующего субъекта. Показана необходимость учета специфики организации инвестиционно-строительной деятельности, действующего национального законодательства, а также особенностей реализации строительных проектов в России, отражающих большой спектр норм, правил и требований, характерных только для отечественного строительного комплекса. Установлено, что один из основных трендов организационного развития проектного управления - связь с новыми концепциями, их интеграция с информатизацией и аддитивными технологиями. Обоснована разработка нормативного документа, определяющего порядок взаимодействий в сфере проектного управления строительством. Подобная регламентация будет способствовать сохранению накопленного опыта устойчивого развития инвестиционно-строительной сферы, его развитию на основе инжиниринга и реинжиниринга для формирования безопасной и комфортной среды жизнедеятельности.
FROM LIKES TO SALES: STUDY ON ENHANCING SOCIAL MEDIA PERFORMANCE FOR INDONESIAN SMES
Authors: M. Rifqy Roosdhani  , Naili Farida  , Farida Indriani
Published: December 2023

Since 2010, social media use for business purposes has seen tremendous expansion. Businesses that implement a solid social media marketing plan may see enhanced results through improved performance on these channels. Though businesses increasingly rely on intuitive and trial-and-error techniques when developing their social media marketing strategy, we identify effective marketing strategies designed for Small and Medium-Sized Enterprises (SMEs) to optimize social media performance. As part of their marketing strategies, SMEs should moderate social media-based customer engagement to achieve maximum leverage. Our study employed quantitative purposive sampling to collect and analyze data from 265 food and beverage SMEs located in Solo, Semarang, Kudus and Jepara. Afterward, we utilized Structural Equation Modelling AMOS data collected through a questionnaire to test our empirical model and validate its prediction capabilities. Our findings demonstrate how effective social media marketing strategies can increase customer engagement with social media-based customer interactions and positively affect performance on these channels. Furthermore, SMEs should utilize brand exposure strategies through social media marketing in order to further boost social media-based customer interactions.
Kesan Nomofobia dalam Kalangan Pelajar Sekolah Menengah di Kawasan Kuching
Authors: Zaidi Juwita
Published: December 2023

Nomofobia dianggap sebagai gangguan kepada komuniti digital dan maya yang kontemporari dan merujuk kepada ketidakselesaan, kegelisahan apabila tidak ada liputan jaringan atau kehabisan bateri atau penderitaan disebabkan oleh tidak dapat menggunakan telefon bimbit atau komputer. Penyataan masalah bagi kajian ini ialah masalah nomofobia telah mengakibatkan pengguna maut, iaitu seorang remaja berumur 16 tahun maut disebabkan renjatan elektrik ketika beliau memakai earphone. Hal ini juga boleh berlaku apabila seseorang itu asyik bermain telefon pintar mereka ketika mengecas bateri telefon. Disebabkan ketagihan mereka untuk bermain telefon boleh meragut nyawa mereka sendiri. Seseorang itu ketagih terhadap telefon pintar mereka disebabkan terlalu leka bermain permainan atas talian, ketagih terhadap media sosial seperti Facebook, Instagram dan lain-lain. Objektif kajian ialah mengenalpasti faktor nomofobia dan kesan nomofobia. Pendekatan kuantitatif telah dijalankan di kalangan pelajar di SMK Semerah Padi dan SMK Matang Jaya. Sebanyak 53 orang pelajar SMK Semerah Padi manakala sebanyak 47 orang pelajar SMK Matang Jaya. Hasil soal selidik mendapati bahawa sebanyak 23 orang dari SMK Semerah Padi dan 18 orang responden dari SMK Matang Jaya tidak pasti sama ada mereka semakin ketagih dengan telefon atau pun tidak
Presentación atípica de teratoma quístico maduro gigante en una paciente adolescente
Authors: Machado Bernal Jaime Andrés , Acosta Mendoza Dewi Isabel
Published: December 2023

Introducción: El teratoma quístico maduro es un tipo de tumor derivado de las células germinales que aparece en pacientes en edad fértil. La edad más frecuente de aparición de este tipo de tumores es entre los 20 – 40 años.
Caso clínico: Se presenta el caso de una paciente adolescente de 18 años con masa abdominal gigante de crecimiento abrupto cuya presentación fue atípica dado el tamaño de esta, el cual se manifestó con dolor abdominal agudo.
Tratamiento: Se realiza resección de la masa la cual confirma diagnóstico histopatológico de teratoma quístico maduro.
Conclusión: Este tipo de patologías rara vez se presentan con un crecimiento tan exagerado como el caso de la paciente en mención, la resolución quirúrgica sigue siendo el gold estándar en cuanto al tratamiento.
Pengelolaan Arsip Elektronik di Era Digital
Authors: Wulandari Dellia Santi , Ismaya
Published: December 2023

Dengan waktu dan teknologi, memudahkan manajemen pekerjaan, juga dalam pengarsipan. Perkembangan teknologi informasi memerlukan penanganan dokumen secara elektronik, mengacu pada UU Kearsipan No. 43 Tahun 2009 dan UU No. 11 Tahun 2008 tentang Informasi dan Transaksi Elektronik. Media elektronik sebagai salah satu alternatif dalam pengelolaan arsip muncul karena masih banyaknya permasalahan pengelolaan arsip berbasis kertas. Tujuan penulisan karya ilmiah ini adalah untuk menjelaskan pengelolaan dokumen elektronik dan mengetahui efektifitas pengelolaan dokumen elektronik di Indonesia. Metode yang digunakan dalam penelitian ini didasarkan pada penelitian literatur. Peneliti membaca dan meringkas sumber terpercaya seperti jurnal, makalah penelitian, dan buku. Menurut Read & Ginn, siklus pengelolaan arsip elektronik terdiri dari empat tahap, yaitu: pembuatan dan penyimpanan; distribusi dan penggunaan; pemeliharaan; dan disposisi. Berdasarkan teori efektifitas Gibson, pengelolaan arsip di Indonesia memenuhi tujuh indikator, namun sumber daya manusianya belum maksimal. Dari sini dapat disimpulkan bahwa efektivitas pengelolaan arsip di Indonesia belum sepenuhnya tercapai.
Long-range prediction of the tropical cyclone frequency landfalling in China using thermocline temperature anomalies at different longitudes
Authors: Liu Chunlei , Zheng Rong , Jin Liang , Bao Ruijuan , Cao Ning , Liao Xiaoqing , Xue Yufeng , Chen Hailiang , Yang Ke , Su Qianye
Published: December 2023

The landfalls of the tropical cyclone (TC) along the coast of China have caused huge economic damages. There are approximately nine TC landfalls in China every year. It will be beneficial if the landfall frequency can be predicted in advance. Inspired by the study of Sparks and Toumi (Commun Earth Environ, 30-1-2020), six datasets, including four ocean reanalyses and two object analyses from 1993 to 2019, are employed to study the consistency in the relationship between the thermocline temperature anomalies at different longitudes and the frequency of TC landfalls along the coastal areas of China (South China, East China, and the whole of China). The thermocline temperature anomalies at different longitudes are tested in order to confirm our hypothesis that the eastward and westward transports of ocean heat from the warm pool are the causes of the significant correlations. The results show some significant correlations at various longitudes, and the temperature anomalies can predict the TC landfall frequency for several months or longer. Further study also shows the close relationship between the ocean heat transport and the sea surface temperature anomalies at the genesis locations of TC landfalls. The locations of the western Pacific subtropical high (WPSH) during high-frequency TC landfall years also show favorable spatial patterns to the TC landfall in South China and East China, respectively. In years with a high TC frequency in South China, the westward displacement of the WPSH ridge steers TC toward South China, while during high-frequency TC landfall years in East China, WPSH is located further north, and the westward extension of the ridge is in close proximity to the East China Sea.
Comprehensive evaluation research of hybrid energy systems driven by renewable energy based on fuzzy multi-criteria decision-making
Authors: Chen Xiangyu , Chen Chunsheng , Tian Guang , Yang Yang , Zhao Yunhao
Published: December 2023

The worsening of climate conditions is closely related to the large amount of carbon dioxide produced by human use of fossil fuels. Under the guidance of the goal of “carbon peaking and carbon neutrality goals”, with the deepening of the structural reform of the energy supply side, the hybrid energy system coupled with renewable energy has become an important means to solve the energy problem. This paper focuses on the comprehensive evaluation of hybrid energy systems. A complete decision support system is constructed in this study. The system primarily consists of four components: 1) Twelve evaluation criteria from economic, environmental, technological, and socio-political perspectives; 2) A decision information collecting and processing method in uncertain environment combining triangular fuzzy numbers and hesitation fuzzy language term sets; 3) A comprehensive weighting method based on Lagrange optimization theory; 4) Solution ranking based on the fuzzy VIKOR method that considers the risk preferences of decision-makers. Through a case study, it was found that the four most important criteria are investment cost, comprehensive energy efficiency, dynamic payback period and energy supply reliability with weights of 7.21%, 7.17%, 7.17%, and 7.15% respectively. A1 is the scheme with the best comprehensive benefit. The selection of solutions may vary depending on the decision-maker’s risk preference. Through the aforementioned research, the decision framework enables the evaluation of the overall performance of the system and provides decision-making references for decision-makers in selecting solutions.
Experimental optimization of the Nafion® ionomer content in the catalyst layer for polymer electrolyte membrane water electrolysis at high temperatures
Authors: Li Hua , Huang Senrui , Guan Chao , Wang Huixuan , Nakajima Hironori , Ito Kohei , Wang Yulin
Published: December 2023

The polymer electrolyte membrane water electrolysis (PEMWE) performance is closely related to the Nafion® ionomer content in catalyst layers (CLs). This study experimentally investigates the impact of anode and cathode Nafion® ionomer contents on the PEMWE performance at high temperatures. The Nafion® ionomer content is 5–30 wt% on both anode and cathode sides, while the temperature and operating pressure change from 80°C to 120°C and 0.1 MPa to 0.3 MPa, respectively. Experimental results reveal that elevated temperature and operating pressure can remarkably promote the performance of PEMWE with a reasonable Nafion® ionomer content and without dehydrating the membrane at 120°C and 0.3 MPa. However, the PEMWE performance deteriorates as the Nafion® ionomer content is too low. The anode Nafion® ionomer content has a relatively great impact on ohmic resistance, concentration, and activation overpotential, especially the concentration overpotential. Nevertheless, the cathode Nafion® ionomer content only affects the ohmic resistance. Finally, under the operating conditions of 120°C and 0.3 MPa, employing a Nafion ionomer content of 10 wt% in the anode–cathode sides minimizes the electrolysis voltage to 2.18 V at 18 A/cm2.
Strengthening deep-learning models for intracranial hemorrhage detection: strongly annotated computed tomography images and model ensembles
Authors: Kang Dong-Wan , Park Gi-Hun , Ryu Wi-Sun , Schellingerhout Dawid , Kim Museong , Kim Yong Soo , Park Chan-Young , Lee Keon-Joo , Han Moon-Ku , Jeong Han-Gil , Kim Dong-Eog
Published: December 2023

Background and purpose

Multiple attempts at intracranial hemorrhage (ICH) detection using deep-learning techniques have been plagued by clinical failures. We aimed to compare the performance of a deep-learning algorithm for ICH detection trained on strongly and weakly annotated datasets, and to assess whether a weighted ensemble model that integrates separate models trained using datasets with different ICH improves performance.

Methods

We used brain CT scans from the Radiological Society of North America (27,861 CT scans, 3,528 ICHs) and AI-Hub (53,045 CT scans, 7,013 ICHs) for training. DenseNet121, InceptionResNetV2, MobileNetV2, and VGG19 were trained on strongly and weakly annotated datasets and compared using independent external test datasets. We then developed a weighted ensemble model combining separate models trained on all ICH, subdural hemorrhage (SDH), subarachnoid hemorrhage (SAH), and small-lesion ICH cases. The final weighted ensemble model was compared to four well-known deep-learning models. After external testing, six neurologists reviewed 91 ICH cases difficult for AI and humans.

Results

InceptionResNetV2, MobileNetV2, and VGG19 models outperformed when trained on strongly annotated datasets. A weighted ensemble model combining models trained on SDH, SAH, and small-lesion ICH had a higher AUC, compared with a model trained on all ICH cases only. This model outperformed four deep-learning models (AUC [95% C.I.]: Ensemble model, 0.953[0.938–0.965]; InceptionResNetV2, 0.852[0.828–0.873]; DenseNet121, 0.875[0.852–0.895]; VGG19, 0.796[0.770–0.821]; MobileNetV2, 0.650[0.620–0.680]; p < 0.0001). In addition, the case review showed that a better understanding and management of difficult cases may facilitate clinical use of ICH detection algorithms.

Conclusion

We propose a weighted ensemble model for ICH detection, trained on large-scale, strongly annotated CT scans, as no model can capture all aspects of complex tasks.
Multi-level analysis of the determinants of physical domestic violence against children using longitudinal data from MINIMat mother–child cohort in Bangladesh
Authors: Naved Ruchira Tabassum , Antu Jannatul Ferdous , Parvin Kausar , Ziaei Shirin
Published: December 2023

Objectives

Despite high levels of physical violence against children (VAC) globally (40–50%), the literature on the determinants of VAC remains inconclusive. Most of the literature on this topic is based on cross-sectional data, and the multi-level nature of the drivers of VAC is widely ignored. This leads to model specification problems and an inability to draw causal inferences. Moreover, despite the higher prevalence of VAC in low-and middle-income countries, studies from high income countries dominate the field. We examined the determinants of physical domestic VAC to address these gaps in the literature.

Methods

Data were collected between 2001 and 2020 from 762 mother–child dyads recruited in the Maternal and Infant Nutrition Interventions in Matlab (MINIMat) study in Bangladesh. We conducted multi-level logistic regression analyses to identify the determinants of physical domestic VAC.

Results

Prevalence of physical domestic violence against girls (69%) and boys (62%) was extremely high. Community-level prevalence of physical domestic VAC increased the likelihood of physical domestic VAC at the individual level across gender (girls - OR-5.66; 95% CI- 3.11-10.32; boys - OR-7.67; CI- 3.95-14.91). While physical domestic violence against mothers was not associated with physical domestic violence against girls, it reduced the likelihood of such violence against boys by 47%. Having 3 or more siblings predicted physical domestic violence against girls (OR-1.97; 95% CI- 1.01-3.81 for 3 siblings; OR-4.58; 95% CI- 2.12-9.90 for 4 or more siblings), but not against boys. While girls in Hindu families were more likely to experience this violence, the boys were not. Mother’s education, employment non-governmental organization (NGO) participation and, household wealth did not predict this violence against any gender.

Conclusion

We contend that physical domestic violence against mothers reflects an emphasized patriarchal culture in a family where a boy is less likely to experience physical domestic violence. Social norms and social learning theories explain the greater likelihood of a child experiencing physical domestic violence in a village with a higher level of such violence. We conclude that social norms around physical domestic VAC and patriarchal culture need to be changed to effectively address this violence.
Exploring associations between sprinting mechanical capabilities, anaerobic capacity, and repeated-sprint ability of adolescent ice hockey players
Authors: Glaude-Roy Julien , Pharand Philippe , Brunelle Jean-François , Lemoyne Jean
Published: December 2023

Introduction

Sprinting ability and anaerobic capacities are the determinant variables of the performance of ice hockey players. Recent research in sprinting showed the existence of distinct force–velocity (F–V) profiles, but the link between these profiles and anaerobic capacities remains unclear. This study explores the associations between F–V variables and anaerobic capacities among cohorts of highly trained adolescent ice hockey players.

Methods

Data from 36 men (age, 15.1 ± 0.2 years) and 34 women (age, 16.5 ± 0.7 years) were collected during off-season camps. All athletes completed a 30-m sprint test, a Wingate anaerobic test (WAnT), and a repeated-sprint anaerobic (RSA) test. F–V variables were calculated from the 30-m sprint test. Partial Pearson correlation coefficients for pooled data and Pearson correlation coefficients for individual male and female datasets were calculated.

Results

Among the F–V variables, maximal theoretical velocity and power were moderately to largely associated with WAnT and RSA performance (|r| = 0.30–0.70). Maximal theoretical force was moderately associated with the RSA (r = −0.32 to −0.33).

Discussion

The results indicate the importance for highly trained adolescent players to be able to apply force at high velocities to maximize anaerobic capacities. Important differences between male and female players suggest training priorities may differ according to sex.
Analysis of the Effectiveness of a Freight Transport Vehicle at High Speed in a Vacuum Tube (Hyperloop Transport System)
Authors: Pellicer David S. , Larrodé Emilio
Published: December 2023

This paper shows the development of a numerical analysis model, which enables the calculation of the cargo transport capacity of a vehicle that circulates through a vacuum tube at high speed, whose effectiveness in transport is analyzed. The simulated transportation system is based on vehicles moving in vacuum tubes at high speed, a concept commonly known as Hyperloop, but assuming the vehicles for cargo containers. For the specific vehicle proposed, which does not include a compressor and levitates on magnets, the system formed by the vehicle and the vacuum tube has been conceptually developed, establishing the corresponding mathematical relationships that define its behavior. To properly model the performance of this transport system, it has been necessary to establish the relationships between the design variables and the associated constraints, such as the Kantrowitz limit, aerodynamics, transport, energy consumption, etc. Once the model was built and validated, it was used to analyze the effects of the variation of the number of containers, the operating speed and the tube length, considering the total and specific consumption of energy. After finding the most efficient configuration regarding energy consumption and transport effectiveness, the complete system was calculated. The results obtained constitute a first approximation for the predesign of this transport system and the built model allows different alternatives to be compared according to the design variables.
Optimal Design of a Surface Permanent Magnet Machine for Electric Power Steering Systems in Electric Vehicle Applications Using a Gaussian Process-Based Approach
Authors: Choi Gilsu , Jang Gwan-Hui , Choi Mingyu , Kang Jungmoon , Kang Ye Gu , Kim Sehwan
Published: December 2023

The efficient design optimization of electric machines for electric power steering (EPS) applications poses challenges in meeting demanding performance criteria, including high power density, efficiency, and low vibration. Traditional optimization approaches often fail to find a global solution or suffer from excessive computation time. In response to the limitations of traditional approaches, this paper introduces a novel methodology by incorporating a Gaussian process-based adaptive sampling technique into a surrogate-assisted optimization process using a metaheuristic algorithm. Validation on a 72-slot/8-pole interior permanent magnet (IPM) machine demonstrates the superiority of the proposed approach, showcasing improved exploitation–exploration balance, faster convergence, and enhanced repeatability compared to conventional optimization methods. The proposed design process is then applied to two surface PM (SPM) machine configurations with 9-slot/6-pole and 12-slot/10-pole combinations for EPS applications. The results indicate that the 12-slot/10-pole SPM design surpasses the alternative design in torque density, efficiency, cogging torque, torque ripple, and manufacturability.
Critical Success Factors in the Technology Commercialization Process: A Comparative Case Study of International Licensing Alliances among Small and Medium-Sized Enterprises
Authors: Lysaridis Ioannis , Chountalas Panos T. , Magoutas Anastasios I.
Published: December 2023

In contemporary academia and industry, the commercialization of technology through licensing has emerged as a prevalent strategy. This paradigmatic shift has prompted numerous industrial firms to intensify their focus on technology commercialization as a mechanism to optimize the returns on their research and development investments, while concurrently leveraging their comprehensive technology portfolios. However, despite growing interest in this area, there exists a conspicuous gap in scholarly literature exploring how small and medium-sized enterprises (SMEs) can effectively and efficiently capitalize on this opportunity in a global context. The objective of the present study is to fill this void by offering an in-depth analysis of the key determinants that contribute to the successful commercialization of technology via licensing. Employing a qualitative research methodology, this paper presents a comparative case study that explores four separate international licensing alliances, each formed between the same licensor, specializing in solar mounting system engineering, and four different licensees, all engaged in the production and marketing of this specialized technology. Data were meticulously gathered through a triangulated approach that incorporated interviews with both licensor and licensees, extensive desk research, and on-site observations. Our empirical findings reveal that the critical success factors identified in existing literature are not uniformly significant. Specifically, four elements—relational dynamics, cultural considerations, human capital, and resource allocation—emerged as pivotal in ensuring the successful implementation of technology commercialization strategies. By elucidating these nuanced factors, this study contributes to both academic discourse and practical applications, thereby serving as a valuable resource for SMEs aiming to navigate the complexities of technology commercialization in international settings.
Developments in Wingtip Vorticity Mitigation Techniques: A Comprehensive Review
Authors: Gharbia Yousef , Derakhshandeh Javad Farrokhi , Alam Md. Mahbub , Amer A. M.
Published: December 2023

Wingtip vortices generated from aircraft wingtips, as a result of the pressure differential at the wingtip, constitute a major component of the total drag force, especially during take-off and landing. In addition to the drag issue, these vortices also pose a significant hazard to smaller aircraft flying in the wake of the larger airplane. The wingtip vortices play a crucial role in aerodynamic efficiency, fuel consumption, flight range, and aircraft stability. This paper presents an overview of the volume of work conducted over the past six decades to encapsulate the phenomena and the techniques devised to mitigate the wingtip vortices. It is shown that the aerodynamic efficiency of the examined wingtip devices ranges from 1% to 15%, depending on the type of wingtips and the flight conditions. Furthermore, it is pointed out that the decrease in fuel consumption ranges from 3.4% to 10%, and the reduction in the induced drag ranges from 5% to 20%.