bluuebunny/crossref_metadata_2025 huggingface dataset:
Language and Value Orientations in Higher Education
Authors: Nwosu Chijioke F.
Published: June 2023

Language plays a central role in the life and activities of our world. This article is a theoretical analysis of the dynamic powers of language in driving possible value-based orientations in higher education. The multilingual nature of the continent of Africa and its bilateral lingual experiences during the colonial eras should be considered as both factual and impacting factors in evaluating language dynamics within value orientations and learning in the African case study. To this end, the article attempts to contribute to the fact that there is a need to find or reinstate value in Africa’s linguistics dynamics and its complexities, as well as give them properly structured orientations within the new phase of repositioning Africa in the global spaces.
Music as an Universal Language for Peacebuilding
Authors: Andriamasy Anja
Published: June 2023

Many people claim that music is a universal language considering the impact and beneficial results that it usually triggers, whereas others reject the idea due to contextual or cultural sentiments and parameters that must be considered. Both sides’ arguments make sense but, despite skepticism, music should be considered as a universal language, which becomes clear by depicting it in the context of peacebuilding and by exploring its linguistics and therapeutic effects, through various domains such as philosophy, music theory and the contemporary world. The author argues that considering the counter-arguments and balancing it with this central claim, it is possible to reach an inspiring and complementary common ground between performing arts as music and philosophy.
Review of Dr Hassan Fartousi, A Portrait of Trade in Cultural Goods
Authors: Marceau Gabrielle
Published: June 2023

This is a book review of: Dr Hassan Fartousi, A Portrait of Trade in Cultural Goods in Respect of the WTO and the UNESCO Instruments in the Contexts of Hard-Law and Soft-Law, Theses Series No. 40, Geneva: Globethics Publications, 2023. 493p. Online ISBN: 978-2-88931-529-1
Machines: to Have or to Be?
Authors: Haupt Sabine
Published: June 2023

When we think about “machines”, or “robots”, or “AI”, what comes to our minds is generally an extension of our common relationship with objects in our humane and mundane world: there is a clear distinction between the subject, “we”, and the object. Upon review of some of the most important literary trends of the last centuries, this article invites us to consider the prevalence of this classical ontological division, taking into consideration examples such as Frankenstein, the “brain in a vat” thought experiment, and the last advances towards the reality of “cyborg” beings. The question behind the article bring us to consider to what extent an absolute division between us and machines is still a thing in our days.
pH dependency of photolabile protection groups used for applications in dynamic structural biology
Authors: Pfeifer Yannik , Müller-Werkmeister Henrike M.
Published: June 2023

Photolabile protection groups (PPGs) are important tools in biophysical experiments and allow light-induced spatial and temporal control of compound release. Photocaged substrates are recently driving new experiments in dynamic structural biology, in particular time-resolved serial crystallography (TR-SX) at XFELs and synchrotrons. PPGs are seldom characterized in aqueous conditions, despite their application in biological experiments. Several common PPGs exhibit a strong pH dependency of their absorption spectrum and extinction coefficient, which needs to be considered in experimental planning. We report here the static pH dependent photophysical properties (key absorption bands and corresponding extinction coefficients) of four common PPGs as initial guide for planning time-resolved experiments in dynamic structural biology.
The Effect of Supply Chain Digitalization on Internal Supply Chain Integration of Cement Manufacturing and Distribution Firms in Ghana
Authors: Okyere S. , Osei A. , Akuh R. , Addo L.
Published: June 2023

Purpose: The purpose of this study is to assess the effect of supply chain (SC) digitalization on the internal supply chain integration of firms with a focus on cement manufacturing and distribution firms in Ghana.

Design/Methodology/Approach: The study adopted the cross-sectional quantitative research design from 114 key players and administrative staff of cement manufacturers and distributors in Ghana using a purposive sampling technique and the use of a questionnaire for gathering the data.

Findings: The findings revealed a positive, moderate relationship between the drivers of SC  digitization and internal SC integration; a negative, moderate relationship between the challenges of SC digitization and internal SC integration; a positive, strong correlation between the extent of SC digitization and internal SC integration. All the relationships were significant. Also, the drivers and inhibitors of SC digitisation revealed both positive and negative associations with the extent of  SC integration.

Research Limitation: The selected firms are not fully representing the entire population of cement manufacturing and distribution firms in Ghana, which impact on the external validity of the findings.

Practical Implications: The results will help increase the performance of cement production firms and improve its SC integration. Firms invest resources in the digitalization of its SC to further improve internal SC integration.

 Originality/Value: The study examines the relationship between supply chain digitalization and internal supply chain integration. While digitalization has been widely studied in supply chain management, the specific focus on how it impacts internal supply chain integration in the context of cement manufacturing and distribution firms in Ghana is relatively novel.
Uso y aplicación de células madre en neonatología
Authors: Alvarez Cruz Erika Yolanda , Salinas Martínez René David , Salinas Martínez Ángelo Rigoberto , Bravo Neira Alyssa Geslenny
Published: June 2023

El interés por la utilización de las células madre, ha crecido de forma exponencial en los últimos años. En el área de neonatología, se han adelantado estudios en aplicaciones de las células madre en pacientes con displasia broncopulmonar. Asimismo, el rol inmunomodulador es otro de los beneficios terapéuticos de las células madre, además de un efecto anti apoptosis. Por último, se destaca que este tratamiento puede disminuir la inflamación e incrementar la reparación tisular, a través de un efecto paracrino. Las razones por las cuales esta terapia ha cobrado una gran atención, radican en la identificación, caracterización y aislamiento de las células madre embrionarias humanas y de las expectativas, de alguna forma prematuras, de que las células madre podrían ser capaces de curar innumerables enfermedades (enfermedades neurodegenerativas, cardíacas, endocrinológicas, etc.) gracias a su enorme potencial de diferenciación. En virtud de lo expuesto, la presente investigación tiene como propósito plasmar algunos de los usos y aplicaciones más importantes de las células madre en el área de neonatología. La investigación se llevó a cabo mediante una revisión de tipo documental bibliográfica. Se pudo constatar que existen estudios en diferentes fases, estudios en animales, en humanos, en cualquier caso, son promisorias las investigaciones en curso que han permitido realizar aplicaciones exitosas de células madres en el tratamiento de neonatos con displasia broncopulmonar, lesión pulmonar neonatal inducida por hiperoxia, como método preventivo para evitar el desarrollo de insuficiencia renal, como prevención de hidrocefalia congénita, en la reparación y la regeneración del tejido cerebral dañado tras la agresión hipóxico-isquémica, para el tratamiento del síndrome de hipoplasia del ventrículo izquierdo, entre los más resaltantes. Evidentemente se requiere de más investigaciones y de un control riguroso que permita la administración de las células madre de forma segura y responsable.
Digitalización en el riego 4.0 y la captación de variables climáticas con dispositivos IOT, para optimizar la producción de maíz en un sector de Manabí
Authors: Gallegos Zurita Diana Ercilia , Rodriguez Castillo Karen Betzabe , Ortiz Mosquera Neiser Stalin
Published: June 2023

El propósito de este estudio es realizar un prototipo de sistema automatizado que permita el monitoreo, control, almacenamiento de la información y toma de decisiones para el riego, para el manejo eficiente de las variables climáticas que afectan a los cultivos de maíz en un sector de Manabí. Para esto se requiere realizar una investigación bibliográfica y de campo, de tal manera que permita identificar parámetros de las variables que afectan el cultivo de maíz en la zona, luego de esto se debe seleccionar adecuadamente los dispositivos eléctricos y electrónicos para el registro de la medición a controlar, luego se desarrolla un sistema con un servidor para el monitoreo, control y almacenamiento de información obtenida de los sensores, para finalmente validar el prototipo en el sitio. Con el desarrollo de este prototipo de toma de decisiones, se pudo brindar asesoramiento a los agricultores para aprender a gestionar de forma directa y eficaz sus terrenos, por ende, tener mayor asertividad en la producción, lo que lleva a una mejor utilidad en sus cosechas, de manera rentable y sostenible.
El desafío de la Industria 4.0 en la educación superior de Ingeniería Industrial: Una revisión sistemática de la literatura
Authors: Macías-Suárez Pilar Tatiana , Pilacuan-Bonete Luis Manuel , Ugalde Vicuña José Willian
Published: June 2023

Con la llegada de la Industria 4.0, se está impactando la educación superior en el campo de la Ingeniería Industrial. La Industria 4.0 representa una nueva era de digitalización y automatización en la fabricación y producción, lo que requiere habilidades y competencias actualizadas por parte de los ingenieros industriales. El estudio realiza una revisión sistemática de la literatura de los últimos 10 años en las bases de datos de Scopus y Web Of Scienc, identificando por medio de un modelado de tópicos de Asignación Latente de Dirichlet (LDA) los desafíos claves que enfrentan las instituciones educativas, las organizaciones y los profesionales de la ingeniería industrial en este contexto. Entre los 8 tópicos encontrados, se visualizaron algunos desafíos destacados, como la necesidad de actualizar los planes de estudio para incluir temas relevantes como Procesos Productivos Inteligentes, Aprendizaje de destrezas digitales, Desarrollo de habilidades digitales en las organizaciones, entre otras, así como la importancia de fomentar habilidades transversales como el pensamiento crítico. Se concluye resaltando la importancia de abordar estos desafíos mediante la colaboración entre la industria y las instituciones educativas, para mantener actualizadas las habilidades de los ingenieros industriales en el entorno de la Industria 4.0.
Análisis comparativo de protocolos de enrutamientos aplicados en WSN utilizadas en ambientes industriales
Authors: Trujillo Borja Ximena Fabiola , Sánchez Delgado Mario Alfredo , Ávalos Gómez Michael Jordy , Ortiz Mosquera Neiser Stalin
Published: June 2023

Las redes de sensores inalámbricos han ganado un amplio campo de aplicaciones incluyendo a la industria 4.0 que se caracteriza por incorporar en sus procesos tecnologías como IoT, automatización, inteligencia artificial, análisis de datos, así las telecomunicaciones se incorporan como un eje transversal que permite mejorar los sistemas de comunicación en los ambientes industriales. El análisis comparativo presentado se realiza entre AODV, DSR, DSDV que son protocolos de enrutamiento que se pueden utilizar basados en los requerimientos de la calidad de servicio que debe cumplir una red, involucrando factores como el tiempo de retardo en la transmisión de paquetes, el ancho de banda, el rendimiento, la cantidad de nodos utilizados, la velocidad de transmisión. Se utilizó el software NS-2 para simular los escenarios que recreen el cambio del número de nodos, velocidad de transmisión y tamaño de bits en la conformación de los paquetes. Para el análisis estadístico de los datos obtenidos se utilizó la prueba anova con una hipótesis de similitud entre los tres protocolos, de los resultados se destaca que en cuanto al mayor rendimiento y el menor retardo los tres protocolos son similares, para el menor ancho de banda DSR y DSDV son similares descartando a AODV.
La teoría pedagógica y la instrucción
Authors: Lindao Alejandro David Salvador , Jiménez Moya Lucia Edith , Alvarado Seguich Carlos Clemente , Hidalgo Tuarez Maria Fernanda
Published: June 2023

El desarrollo de técnicas, metodologías y sistemas que proporcionen un mejoramiento de las cualidades integrales del individuo mediante el proceso de aprendizaje ha sido un tema que no pierde vigencia en el área de la educación en todo el mundo. En este sentido, la importancia de las teorías de aprendizaje o educacionales representan las bases de estas técnicas, métodos o sistemas fundamentales para el mejoramiento de la educación. En la actualidad, se ha convertido en un tema de investigación de mucho interés el desarrollado una gran variedad de teorías para el entendimiento del aprendizaje, así como de los factores de percepción positiva y negativa que infieren directa e indirectamente en el proceso de retención de conocimientos. En consecuencia, el presente estudio tiene como propósito fundamental plasmar las principales generalidades acerca de las teorías pedagógicas y de la instrucción. El tipo de investigación llevado a cabo fue de tipo documental bibliográfica bajo una modalidad de revisión. De los resultados se desprende que la teoría de la instrucción se preocupa por los procesos de compresión, transformación, almacenamiento y uso de la información envueltos en la cognición, mientras que las teorías pedagógicas hacen referencia a un conjunto de conceptos, definiciones, preposiciones, enunciados, principios que interrelacionados permiten explicar y comprender lo pedagógico. Ambas con un respaldo científico amplio. Estas teorías, aplicadas de acuerdo a las necesidades de cada institución, cada población y cada estudiante, en particular, pueden ser capaces de elevar la calidad de la formación integral. Asimismo, brindan una base valiosa para comprender la forma en que aprenden las personas y para desarrollar planes, estrategias o métodos que permitan obtener los mejores resultados en la educación. La incorporación de estas teorías en el diseño educativo permitirá a los educadores crear experiencias de aprendizaje más efectivas.
Severe and fatal neonatal infections linked to a new variant of echovirus 11, France, July 2022 to April 2023
Authors: Grapin Mathilde , Mirand Audrey , Pinquier Didier , Basset Aurélie , Bendavid Matthieu , Bisseux Maxime , Jeannoël Marion , Kireche Bérengère , Kossorotoff Manoelle , L’Honneur Anne-Sophie , Robin Lila , Ville Yves , Renolleau Sylvain , Lemee Véronique , Jarreau Pierre-Henri , Desguerre Isabelle , Lacaille Florence , Leruez-Ville Marianne , Guillaume Clémence , Henquell Cécile , Lapillonne Alexandre , Schuffenecker Isabelle , Aubart Mélodie
Published: June 2023

We report nine severe neonatal infections caused by a new variant of echovirus 11. All were male, eight were twins. At illness onset, they were 3–5 days-old and had severe sepsis and liver failure. This new variant, detected in France since April 2022, is still circulating and has caused more fatal neonatal enterovirus infections in 2022 and 2023 (8/496; 1.6%, seven associated with echovirus 11) compared with 2016 to 2021 (7/1,774; 0.4%). National and international alerts are warranted.
ECONOMIC CRISES AND SPORTS MEGA-EVENTS: LEARNING FROM PAST EXAMPLES FOR FUTURE ANALYSES
Authors: Steve Georgakis , Boris Morozov , John Nauright
Published: June 2023

İntroduction. The Athens Olympic Games of 2004 contributed to the subsequent Greek economic crisis due to irresponsible spending. The aim of our study was to show how the policies and spending of the Greek government for infrastructural and other Olympic related projects links with a pattern of financial irresponsibility that led to the collapse of the Greek economy. Material and methods. Our methods were to examine governmental policies and financial indicators surrounding sport mega events (SMEs) and specifically the Greek case surrounding the 2004 Olympics. Results. Our results show that the current analysis of SMEs do not adequately examine financial indicators and realities and that both economic and financial analyses are necessary when determining both costs and return on investment.
CURRENT DEVELOPMENT TRENDS OF AMATEUR FOOTBALL IN UKRAINE
Authors: Igor Doroshenko , Andrii Svatyev , Eduard Sobol , Sviatoslav Danylchenko , Eduard Doroshenko
Published: June 2023

Introduction. Scientists studying the development of football emphasize that professional football is a kind of core or top of the conditional structure of the modern football industry, and its basis is amateur football. In this context, it is clear that amateur football is a necessary prerequisite for the effective development of professional football in the country. The purpose of the study is to analyze and systematize the current state and generalize the ways of development of amateur football in Ukraine, taking into account regional aspects for the period 2018-2023. Research methods: analysis and generalization of data from scientific and methodological literary sources and the Internet network, pedagogical observations, content analysis of materials of the official websites of regional football associations, amateur football associations of Ukraine, the Ukrainian Football Association, the International Federation of Football Associations (FIFA) for the period of 2018 -2023 years, methods of mathematical statistics. Results. Quantitative indicators of the representation of teams from regional football associations in the group and final tournaments of the Ukrainian football championships among amateur teams for the period 2018-2023 were analyzed. Conclusions. The analysis of the data of the scientific and methodological literature and the global network "Internet" shows that as criteria for the development of amateur football, it is appropriate to use the general quantitative indicators of the representation of amateur football teams from regional football associations in the Ukrainian football championships among amateur teams and the quantitative indicators of the representation of amateur football teams from respective regional associations in the final tournaments of these competitions. According to quantitative indicators of participation in championships of Ukraine, among amateur teams, the leaders are Dnipropetrovsk Oblast (15 teams) and Kyiv City Football Association (13 teams). According to the quantitative indicators of the teams' participation in the final tournaments, the leaders are the representatives of the Sumy and Cherkasy regional football associations, whose teams, in four seasons, participated in the final tournaments of the championship of Ukraine in football among amateur teams three times
IMPLEMENTATION OF THE BASIC PRINCIPLES OF ACADEMIC INTEGRITY INTO THE EDUCATIONAL PROCESS OF SPECIALISTS IN THE SPECIALTY 017 PHYSICAL CULTURE AND SPORTS AT BORIS GRINCHENKO KYIV UNIVERSITY
Authors: Halyna Ivanenko , Olena Yarmoliuk , Olha Musiiachenko
Published: June 2023

Introduction. Due to the constant development of information and communication technologies, we have received an almost unlimited opportunity to search and distribute information. However, this immensity has caused the emergence of such negative consequences as the spread of academic dishonesty in educational and scientific activities. The actualization of issues of academic integrity in the conditions of the distance format of the educational process, which was implemented in Ukraine during the COVID-19 pandemic and continued due to the establishment of martial law in the country, is also of particular importance. Therefore, it is necessary to continue to pay close attention to the issue of academic integrity to comply with moral and ethical principles both in educational activities in higher education establishments and in the writing of scientific works by scientific and pedagogical workers and students. Aim is to investigate the implementation of the main tasks of academic integrity in the educational process of specialists in the field of physical culture and sports (on the example of Borys Grinchenko Kyiv University). Material and methods: analysis and synthesis of scientific and methodological literature, documentary sources, systematization and generalization, interrogation. The results. The system of preventing and stopping manifestations of academic dishonesty, which is implemented at the Borys Grinchenko Kyiv University, is characterized. It was determined that this system consists of five interconnected parts. Conclusions. The research made it possible to determine how the main principles of academic integrity are being implemented at the Borys Grinchenko Kyiv University. The aspects related to the interaction of teachers and applicants regarding informing about the need to observe academic integrity in their activities were characterized.
An excursion to the border of decidability: between two- and three-variable logic
Authors: Fiuk Oskar , Kieronski Emanuel
Published: June 2023

With respect to the number of variables the border of decidability lies between 2 and 3: the two-variable fragment of first-order logic, FO2, has an exponential model property and hence NExpTime-complete satisfiability problem, while for the three-variable fragment, FO3, satisfiability is undecidable. In this paper we propose a rich subfragment of FO3, containing full FO2 (without equality), and show that it retains the finite model property and NExpTime complexity. Our fragment is obtained as an extension of the uniform one-dimensional variant of FO3.
Tighter Abstract Queries in Neural Network Verification
Authors: Cohen Elazar , Elboher Yizhak Yisrael , Barrett Clark , Katz Guy
Published: June 2023

Neural networks have become critical components of reactive systems in various do- mains within computer science. Despite their excellent performance, using neural networks entails numerous risks that stem from our lack of ability to understand and reason about their behavior. Due to these risks, various formal methods have been proposed for verify- ing neural networks; but unfortunately, these typically struggle with scalability barriers. Recent attempts have demonstrated that abstraction-refinement approaches could play a significant role in mitigating these limitations; but these approaches can often produce net- works that are so abstract, that they become unsuitable for verification. To deal with this issue, we present CEGARETTE, a novel verification mechanism where both the system and the property are abstracted and refined simultaneously. We observe that this approach allows us to produce abstract networks which are both small and sufficiently accurate, allowing for quick verification times while avoiding a large number of refinement steps. For evaluation purposes, we implemented CEGARETTE as an extension to the recently proposed CEGAR-NN framework. Our results are highly promising, and demonstrate a significant improvement in performance over multiple benchmarks.
A Fast and Accurate ASP Counting Based Network Reliability Estimator
Authors: Kabir Mohimenul , Meel Kuldeep S
Published: June 2023

The quantification of system reliability is fundamental to the assessment of a system’s safety and resilience, and has been of interest to decision-makers. Since quantifying the system reliability is shown to be computationally intractable, researchers aim to find approximations. Existing approaches to approximate reliability either suffer from poor scalability or lack of correctness guarantees. Answer Set Programming (ASP) is a powerful tool for knowledge representation that can specify complex combinatorial problems. In recent years, the new applications of ASP have propelled the emergence of well-engineered ASP systems. This paper proposes a new ASP counting based framework, RelNet-ASP, to approximate or estimate the reliability of a system or network. The framework reduces the problem of reliability estimation to an approximate model counting problem on ASP programs, offering formal guarantees of the estimated reliability. The experimental evaluation demonstrates that RelNet-ASP outperforms state-of-the-art techniques in terms of both runtime performance and accuracy.
On the Complexity of Convex and Reverse Convex Prequadratic Constraints
Authors: Raya Rodrigo , Hamza Jad , Kuncak Viktor
Published: June 2023

Motivated by satisfiability of constraints with function symbols, we consider numerical inequalities on non-negative integers. The constraints we address are a conjunction of a linear system Ax = b and an arbitrary number of (reverse) convex constraints of the form xi ≥ xdj (xi ≤ xdj ). We show that the satisfiability of these constraints is NP-complete even if the solution to the linear part is given explicitly. As a consequence, we obtain NP- completeness for an extension of certain quantifier-free constraints on sets with cardinalities and function images.
The clinical effectiveness of a falls rapid response service, and sex differences of patients using the service: a cross-sectional study in an English ambulance trust
Authors: Charlton Karl , Stagg Hayley , Burrow Emma
Published: June 2023

Background: Falls in older adults are an important issue internationally. They occur from complex interactions between biological, environmental and activity-related factors. As the sexes age differently, there may be sex differences regarding falls. This study aimed to determine
the clinical effectiveness of a falls rapid response service (FRRS) in an English ambulance trust and to identify sex differences between patients using the service.Methods: A cross-sectional study between December 2018 and September 2020. Patients aged ≥ 60 years who had fallen
within the study area were included. The FRRS comprised a paramedic and occupational therapist and responded 07:00‐19:00, 7 days per week. Anonymised data regarding age, sex and conveyance were collected for all patients attended by the FRRS and standard ambulance crews. Clinical data
regarding fall events were collected from consenting patients attended by the FRRS only.Results: There were 1091 patients attended by the FRRS versus 4269 by standard ambulance crews. Patient characteristics were similar regarding age and sex. The FRRS consistently conveyed fewer
patients versus standard ambulance crews (467/1091 (42.8%) v. 3294/4269 (77.1%), p = < 0.01). Clinical data were collected from 426/1091 patients attended by the FRRS. In these patients, women were more likely to reside alone than men (181/259 (69.8%) v. 86/167 (51.4%), p
= < 0.01), and less likely to experience a witnessed fall (16.2% v. 26.3%, p = 0.01). Women had a higher degree of comorbidity specific to osteoarthritis and osteoporosis, while men were more likely to report a fear of falling score of 0 (35.3% v. 22.7%, p = < 0.01).Conclusion:
The FRRS is clinically effective regarding falls compared to standard ambulance crews. Sex differences existed between men and women using the FRRS, indicating women are further along the falls trajectory than men. Future research should focus on demonstrating the cost effectiveness of the
FRRS and how to better meet the needs of older women who fall.
Prevalencia de asma en pacientes hospitalizados por neumonía asociada a infección por SARS-CoV-2
Authors: Paz-Velarde Beatriz Alejandra , Arellano-Arteaga Kevin Javier , Bedolla-Pulido Angie , Morales-Romero Jaime , Rodríguez-Lizola Juan Manuel , Bedolla-Barajas Martín
Published: June 2023

Antecedentes: La asociación el asma con la COVID-19 continúa siendo controversial. Objetivo: establecer la prevalencia de asma en una muestra de pacientes con neumonía asociada COVID-19; además, describir las características clínicas de los pacientes con asma en comparación con los pacientes sin asma.
Métodos: Se analizaron los datos clínicos correspondientes a120 pacientes hospitalizados por neumonía asociada a infección por SARS-CoV-2. Los pacientes con y sin asma fueron comparados en función de la gravedad de la COVID-19.
Resultados: La prevalencia de asma en los pacientes con neumonía por COVID-19 fue del 3.5% (IC 95%: 1.5% a 9.6%). Al comparar la gravedad de la COVID-19 entre los pacientes con asma con los pacientes sin asma, ésta no difirió en función de los síntomas, la comorbilidad, la duración de los síntomas, la necesidad de ventilación mecánica asistida, los biomarcadores de inflamación y la ocurrencia de muerte. Los pacientes con asma y COVID-19 mostraron un fenotipo T2 alto, con pobre función respiratoria y sin uso de tratamiento regular para el control del asma.
Conclusiones: No se observaron diferencias significativas en la frecuencia de la ventilación mecánica asistida o de la muerte entre los pacientes hospitalizados por neumonía asociada con COVID-19 con y sin historia de asma.
Palabras clave: asma; COVID-19; prevalencia; SARS-CoV-2.
Vía aérea pequeña: de la definición al tratamiento
Authors: Gochicoa-Rangel Laura , Jiménez-González Carlos Adrián , Lechuga-Trejo Irma , Benítez-Pérez Rosaura Esperanza , Thirión-Romero Ireri , Hernández-Rocha Federico Isaac , Ceballos-Zúñiga Omar , Cortés-Télles Arturo , Guerrero-Zúñiga Selene , Díaz-García Roberto , Hernández-Morales Aloisia Paloma , Aguilar-Zanela Jacqueline Lorena , Torre-Bouscoulet Luis
Published: June 2023

La vía aérea pequeña, presente desde los orígenes de la humanidad y descrita hace apenas un siglo, se ha descubierto recientemente como el sitio anatómico donde inicia la inflamación provocada por algunas enfermedades pulmonares obstructivas: asma y enfermedad pulmonar obstructiva crónica (EPOC), per se. Se ha identificado disfunción de la vía aérea pequeña en el 91% de los pacientes asmáticos y en una gran proporción de quienes padecen EPOC. En los pacientes sin enfermedad, la vía aérea pequeña representa el 98.8% (4500 mL) del volumen pulmonar total, y solo aporta del 10 al 25% de la resistencia pulmonar total; sin embargo, en sujetos con obstrucción puede suponer el 90% de la resistencia total. A pesar de esto, sus características morfológicas y funcionales permiten que la disfunción pase inadvertida por métodos diagnósticos convencionales, por ejemplo la espirometría. Con base en lo anterior, el objetivo de este estudio fue revisar el panorama general de los métodos disponibles para evaluar la vía aérea pequeña y los posibles tratamientos asociados con esta zona silente.
Palabras clave: Vía aérea pequeña; resistencia al flujo aéreo; asma; EPOC.
Reducción del contenido de IgA1 e IgA2 en la leche materna por efecto de la pasteurización y congelación
Authors: López-Marin Beatriz , Osorno-Gutiérrez Adriana Patricia , Arredondo-Vanegas Natalia
Published: June 2023

Objetivo: Determinar el efecto de la pasteurización y congelación en el contenido de IgA1 e IgA2 en la leche materna. Métodos: Estudio observacional y retrospectivo, llevado a cabo en mujeres que tuvieran más de 30 días de ofrecer lactancia a su neonato, y pudieran donar 50 mL de leche. Se determinó la concentración de IgA1 e IgA2 mediante turbidimetría, antes y después de someterse a pasteurización y congelación, cada 15 días durante 2 meses. La congelación fue a –20°C. Se encontró un contenido total de IgA de 1598,5 mg/dL. Resultados: Se seleccionaron 10 donantes de leche materna. La concentración inicial de IgA1 e IA2 fue de 651 y 945.7 mg/dL, respectivamente; al finalizar los tiempos de congelación disminuyó el contenido de ambas inmunoglobulinas: IgA1 del 74% e IgA2 del 86%. Después de los tratamientos, el contenido de inmunoglobulinas disminuyó de forma contundente, con diferencia significativa de p < 0.05. Conclusión: La pasteurización y la congelación afectan de manera importante el contenido de IgA1 e IgA en la leche materna; por tanto, la alimentación al seno materno sigue siendo la mejor forma de ofrecer toda protección inmunológica al lactante. Palabras claves: Leche materna; inmunoglobulinas; IgA1; IgA2; pasteurización; congelación, turbidimetría.
Vasculitis leucocitoclástica como efecto adverso del propiltiouracilo. Reporte de un caso
Authors: Cortés-Guzmán José Santiago , Veloza Karen T. , Domínguez Juan D. , Pinzón-Tovar Alejandro
Published: June 2023

Antecedentes: La causa más frecuente de hipertiroidismo es la enfermedad de Graves. El propiltiouracilo es uno de los medicamentos más prescritos para esta enfermedad. Uno de los efectos adversos dermatológicos del propiltiouracilo es la vasculitis leucocitoclástica.
Reporte de caso: Paciente femenina de 18 años, alérgica al metamizol, con vasculitis asociada a ANCAs, con características de vasculitis leucocitoclástica provocada por el consumo de propiltiouracilo. No se observó afectación sistémica. Dos meses después de suspender el propiltiouracilo desaparecieron casi por completo las lesiones en la piel.
Conclusiones: La vasculitis leucocitoclástica debe considerarse en el espectro de complicaciones provocadas por el consumo de propiltiouracilo. Las lesiones pueden manifestarse con el paso del tiempo, desde unas semanas hasta años después de consumir el fármaco. Cuando no existe afectación sistémica, la suspensión del propiltiouracilo es suficiente para detener la enfermedad.
Palabras clave: Hipertiroidismo; enfermedad de Graves; propiltiouracilo; vasculitis asociada con anticuerpos anti-citoplasma del neutrófilo; vasculitis leucocitoclástica.
ANALYSIS OF ATMOSPHERIC DYNAMICS DURING TAILWIND PHENOMENA ON THE RUNWAY OF KUALANAMU AIRPORT
Authors: Tambunan Nensy Nindy , Frida Erna , Darmawan Yahya
Published: June 2023

A tailwind, a wind component in aviation, can pose risks during aircraft takeoff and landing by blowing from the aircraft's rear. At Kualanamu Airport on August 02, 2022, Air Navigation Indonesia (AirNav) reported an incident where an aircraft had to abort landing due to a tailwind on the runway. This study analyzes the atmospheric dynamics contributing to tailwind disruptions on that specific day. The analysis involved various steps, including assessing upper-level air humidity using reanalysis data processed with the GrADS application, evaluating air instability through the computation of TT, KI, and SI indexes using the RaOB application, and examining cloud formation using Himawari-9 EH satellite imagery. The analysis revealed the presence of Cumulonimbus clouds around Deli Serdang Regency on August 02, 2022, which led to tailwind effects at Kualanamu Airport. Cumulonimbus clouds are often associated with unstable atmospheric conditions and can generate severe weather events like thunderstorms, heavy rainfall, and strong winds. Cumulonimbus clouds indicate the likelihood of convective activity and strong winds. The strong winds caused by these clouds probably disrupted the Tailwind on the runway at Kualanamu Airport.
Effectiveness of Learning Management System in the Student Learning Process in the Pandemic Era of the Covid-19
Authors: Qamarya Nurul , Sriyanah Nour , Wijayanti Lumastari Ajeng , Sari Iramaya , Suprapto Suprapto
Published: June 2023

The purpose of the study is to determine the effectiveness of the learning management system in improving the ability of the student learning process. This research is a quantitative descriptive study. The data analysis used is to use the one-sample t-test. The data normality test is carried out before the test of one sample t-test as a prerequisite. The sample in this study was 35 students. The results showed that the average student activity while using the learning management system in the learning process of the teaching material development course has increased. In addition, the average ability score of students who obtain learning using the learning management system > 77 is met so that it can be said to be effective. Based on the results of the normality test calculations shows that the normal distribution data with a Shapiro-Wilk significance of 0.060 > 0.05. Meanwhile, based on the One Sample t-test shows that the learning management system significantly impacts students' abilities with a significance value of 0.005 < 0.05, which means that the learning management system is effectively used in the learning process.
Characteristics of Nutrition Intake in Diabetic Ulcer Patients at Hospital dr. Slamet Garut
Authors: Farhan Zahara , Alfiansyah Rudi , Ratnasari Devi , Suliyawati Eti
Published: June 2023

Diabetes mellitus can lead to the development of ulcers on the extremities, which are typically caused by peripheral nerve disorders, infections, and blood flow disorders. Managing diabetes requires adhering to proper nutritional intake, including the frequency and duration of meals, as well as the types of foods consumed. In this study, we aimed to examine the nutritional intake characteristics of outpatients with diabetic ulcers at Dr. Slamet Garut, including their eating frequency, meal duration, and food choices. We used a quantitative descriptive research design and selected a sample of 49 diabetic ulcer patients through purposive sampling. Data was collected using a validated and reliable questionnaire. The results of our study indicated that the majority of patients (57.1%) did not eat frequently, had short meal durations (51.0%), and consumed low-calorie foods (61.2%). Diet planning is a major component of success in treating diabetic ulcers. The accuracy and regularity of the patient in setting the amount, type and schedule of meals aims to control glucose levels so that blood flow to the ulcer area becomes smooth and the ulcer healing process will run well. Overall, nutritional intake in patients with diabetic ulcers is largely inadequate during the wound healing process.
A Comparative Analysis of Achievement Emotions by Science Achievement Situation Perceived by Science Gifted Students in General and Gifted Science Class
Authors:   Korean Science Education Society for the Gifted, Sung SeungMin , Kim Sumi , Yeo Sang-Ihn
Published: June 2023

In this study, the achievement emotions of each science achievement situation perceived by science gifted students in general and gifted science class were compared and analyzed. The subjects of the study were 165 science gifted students of the G gifted education institute attached to university. The achievement emotions scale for each science achievement situation used in this study was used by modifying and supplementing the previous study scales. As a result of the study, it was found that science gifted students had statistically significant differences in some achievement emotions in science class and science learning, and there was no statistically significant difference in all achievement emotions in science test achievement situation. In addition, it was found that there was a statistically significant difference in some achievement emotions in science class, science learning, and science test achievement situations according to gender. Based on these research results, implications for achievement emotions by science class, science learning, and science test in general and gifted science class perceived by science gifted students were suggested.
Scheduling Algorithm for Test Period to Increase Student Satisfaction
Authors:   Korean Science Education Society for the Gifted, Han Ye Rim , Cho Min Joon , Kim Jae Sook
Published: June 2023

The introduction of the high school credit system has increased the number of subjects available to students, resulting in unique exam schedules for each student. Our goal is to minimize manual effort and create exam schedules that meet specific requirements. To achieve this, we utilize exhaustive search techniques to ensure that each student’s enrolled subjects are included in their exam schedule. We measure student fatigue using an objective function that takes into account their satisfaction with each subject and its placement. We continuously generate schedules with lower average and standard deviation of fatigue for each student. To further optimize the schedules, we consider additional constraints such as grouping subjects that cannot be scheduled on the same day and taking into account the number of exam rooms available. Given the large number of possibilities involved in the search, we sort subjects and exam times according to fatigue levels and prioritize the search for difficult-to-allocate subjects and exam times. This reduces search time and allows us to create schedules more efficiently.
A Study on Siebeck-Marden’s Theorem of Convex Quadrilaterals
Authors:   Korean Science Education Society for the Gifted, Yoon Juno , Lee Junehee , Hwang Seokhoon , Cho Youngmin
Published: June 2023

This study was based on the research results conducted as an R&E project for gifted students with financial support from the Korea Foundation for the Advancement of Science and Creativity. In this study, we extended Siebeck-Marden’s Theorem, which holds for triangles, into arbitrary convex quadrilaterals. Through this study, the following results were obtained. First, we found and proved the ratio in which the inellipse of a parallelogram divides each side. Second, we discovered Siebeck-Marden’s Theorem for exellipses. We discovered Siebeck-Marden’s Theorem regarding the location of the foci of an exellipse of a triangle. Third, we defined and proved Siebeck-Marden’s Theorem of arbitrary convex quadrilaterals. We defined Siebeck-Marden’s Theorem regarding the location of the foci of an inellipse of an arbitrary convex quadrilateral. In this study, we extended Siebeck-Marden’s Theorem from triangles to convex quadrilaterals. It is expected to contribute to the development of mathematics by enhancing mathematical concepts and properties, just as we extended Siebeck-Marden’s Theorem to arbitrary convex quadrilaterals. Furthermore, this study is expected to encourage further research on the inellipse of convex quadrilaterals.
Social factors behind rising trends of intentional ingestions of caustic agents in adult population of Pakistan. A study from tertiary health care center, Islamabad.
Authors: Shafat Khatoon  , Aijaz Ahmed Sand
Published: June 2023

Objective To evaluate factors associated with rising trends of intentional ingestion of caustic agents for suicidal attempts in Pakistan. Study Design: Cross Sectional, Observational study. Setting: Tertiary Health Care Center of Islamabad. Period: January 2019 to December 2020. Material & Methods: One hundred subjects with intentional ingestion of caustic ingestion treated in Gastroenterology unit were interviewed on a written questioner after their recovery and informed consent. Non-probability purposive was sampling method used. Results: Out of 100 patients 63% were female, mean age was 28.81 years and 58% had suicidal intension. Disturbed marital/ family life was main factor behind suicidal attempts. (P= 0.025). Conclusion: factors like female gender, younger age, poor socioeconomic status and disturbed marital/ family life in study group had statistically significant association with suicidal intentions.
Histomorphometric effects of energy drink consumption on pancreatic tissue of albino wistar rats.
Authors: Shahnaz Bano Memon  , Sajjad Ali Almani  , Saqib Baloch  , Shahab Hanif  , Ayesha Asad  , Rida Qureshi
Published: June 2023

Objective: To determine the histo-morphometric effects of energy drink consumption in different doses on the pancreatic tissue of Wistar Albino rats. Study Design: Experimental study. Setting: Department of Pharmacology, Isra University, Hyderabad. Period: April 2021 to September 2021. Material & Methods: Thirty healthy albino Wistar rats of body weight 200±20 were included in the study. Rats were divided equally into three groups. Group I (Control), Group II (Low dose energy drink 7.5 ml/day) and Group III (High dose energy drink 15 ml/day). The body weight of all animals was measured. Blood samples were collected for the biochemical analysis including serum glucose, serum insulin level, and oxidative markers. Histo-pathological and morphometric findings were observed. Results: A statistically significant rise in body weight in groups II and III (p<0.05). Significantly increased serum glucose and declined insulin level was seen in group II and III compared with controls (p<0.05). There was a significantly lower level of oxidative markers observed in group III than in groups I and II (p<0.05). The mean pancreatic acini and islets diameter in groups II and III has decreased signiﬁcantly compared with group I (p<0.05). The histo-pathological grading reveals that mild to moderate parenchymal changes in the pancreatic tissue of group II rats compared with group I. While moderate to severe changes were observed in group III compared with group I and II rats.  Conclusion: Caffeinated energy drink consumption results in oxidative stress and degenerative changes in the potential to seriously alter the exocrine and endocrine pancreas' normal morphology consumption.
AS ATMOSFERAS DO SER-TÃO: DA PALAVRA À NOVELA GRÁFICA
Authors: Abreu Isabela Nunes de , Muller Adalberto
Published: June 2023

O presente trabalho tem como objetivo analisar as atmosferas presentes na adaptação
em formato de novela gráfica (roteiro por Guazzelli e arte de Rodrigo Rosa) da obra Grande Sertão:
Veredas, de João Guimarães Rosa. De maneira comparativa e experimental, busca-se entender de
que forma a materialidade e a dimensão plástica da novela gráfica contribuem para a construção de
um compartilhamento afetivo e uma tradução de atmosferas presente na obra original de João
Guimarães Rosa.
Sítio da Pesquisa
Authors: Lima Newton Silva de , Ferreira Alan dos Santos
Published: June 2023

Sítio da pesquisa. Equipamento. Método
Resultados (Gráficos TEC, S4, Dst, Kp)
Authors: Lima Newton Silva de , Ferreira Alan dos Santos
Published: June 2023

Resultados gráficos dos índices TEC, S4, Dst, Kp, sobre o alvo (Manaus-Brasil: Lat.: -3,10 e Long.: -59,97) para os anos de 2011 e 2012.
Segmentação de imagens PET para definição de volumes de tratamento em planejamento radioterápico
Authors: Holanda de Oliveira Alex , Lacerda Isabelle , Araújo Jefersson
Published: June 2023

De acordo com as projeções estatísticas do Instituto Nacional do Câncer, estima-se aproximadamente 704.000 novos casos de câncer no Brasil para cada ano do triênio 2023-2025. Uma das principais técnicas para o tratamento desta patologia é a radioterapia. Durante o planejamento radioterápico, é determinada a maneira mais adequada de se irradiar o volume tumoral, buscando minimizar a dose de radiação nos tecidos vizinhos saudáveis. A definição do volume-alvo é geralmente realizada por delineação manual diretamente numa imagem radiológica do paciente pelo radioterapeuta. Isto leva a um maior nível de incerteza visto que esse método de segmentação é subjetivo. Este trabalho busca colaborar na identificação de métodos alternativos de segmentação para definição de volumes em imagens PET (do inglês Positron Emission Tomography), de modo a possibilitar ferramentas alternativas de auxílio aos profissionais no planejamento radioterápico. Para isto, foram comparados métodos de segmentação em imagens do fantoma IEC/NEMA (IEC do inglês, International Electrotechnical Commission e NEMA do inglês, National Electrical Manufacturers Association) utilizando o software ImageJ. Os métodos avaliados foram o threshold, o level sets e o k-means clustering. Dentre esses, o threshold apresentou resultados mais satisfatórios para segmentação de imagens PET. Entretanto, são necessárias mais pesquisas no desenvolvimento de técnicas que realizem de maneira mais precisa a definição do volume-alvo no planejamento radioterápico, principalmente devido ao alto nível de ruído e baixa resolução espacial das imagens PET.