bluuebunny/crossref_metadata_2025 huggingface dataset:
TET3 overexpression facilitates DNA reprogramming and early development of bovine SCNT embryos
Authors: Zhang Jian , Hao Linlin , Wei Qian , Zhang Sheng , Cheng Hui , Zhai Yanhui , Jiang Yu , An Xinglan , Li Ziyi , Zhang Xueming , Tang Bo
Published: June 2020

Somatic cell nuclear transfer (SCNT) has been successfully used for cloning in a variety of mammalian species. However, SCNT reprogramming efficiency is relatively low, in part, due to incomplete DNA methylation reprogramming of donor cell nuclei. We previously showed that ten-eleven translocation 3 (TET3) is responsible for active DNA demethylation during preimplantation embryonic development in bovines. In this study, we constructed TET3-overexpressing cell lines in vitro and observed that the use of these fibroblasts as donor cells increased the blastocyst rate by approximately 18 percentage points compared to SCNT. The overexpression of TET3 in bovine SCNT embryos caused a decrease in the global DNA methylation level of the pluripotency genes Nanog and Oct-4, ultimately resulting in an increase in the transcriptional activity of these pluripotency genes. Moreover, the quality of bovine TET3-NT embryos at the blastocyst stage was significantly improved, and bovine TET3-NT blastocysts possessed more total number of cells and fewer apoptotic cells than the SCNT blastocysts, similar to in vitro fertilization (IVF) embryos. Nevertheless, DNA methylation of the imprinting control region (ICR) for the imprinted genes H19-IGF2 in SCNT embryos remained unaffected by TET3 overexpression, maintaining parent-specific activity for further development. Thus, the results of our study provide a promising approach to rectify incomplete epigenetic reprogramming and achieve higher cloning efficiency.
La espiritualidad de la alegría: legado del carisma salesiano
Authors: Sosa Báez Carmen , González Martín Rafael
Published: June 2020

El presente trabajo quiere resaltar la importancia de la espiritualidad de la alegría como el camino por el que se debe avanzar en la vida cristiana para conseguir nuestro verdadero ser cristiano y llevarnos a un estado permanente de felicidad. También dejar claro que cualquier reflexión o propuesta que realicemos sobre la espiritualidad de la alegría ha de tener presente y en cuenta una misión pastoral que favorezcan las experiencias de la alegría del Evangelio. Se propone el carisma salesiano como propuesta de santidad desde una alegría profunda en lo cotidiano. Don Bosco repetía constantemente: “Para nosotros la santidad consiste en estar siempre alegres”.
Crowdsourcing durch Ideenwettbewerbe
Authors: Schultz Christian , Mattick Dmitry
Published: June 2020

Ideenwettbewerbe sind ein vielversprechender Weg für Unternehmen, um Impulse für Innovationen zu generieren. Durch Crowdsourcing stehen dem Unternehmen eine Vielzahl von Möglichkeiten zur Verfügung, um Ideenwettbewerbe mit hoher Reichweite auszurichten. Jedoch sollten verschiedene Erfolgsfaktoren, wie Planung und Vorbereitung, Förderung der Teilnehmermotivation und Betreuung der Teilnehmer durch den Moderator, beachtet werden.
Eigentum verpflichtet: Gilt auch für Algorithmen
Authors: Groß Christian , Wagner Gert G.
Published: June 2020

Ob selbstfahrende Autos oder Schufa-Score: Algorithmen sind nicht so geheimnisvoll und Scores bei Weitem nicht so exakt, wie fast alle glauben. Die Methode zu ihrer Überprüfung ist von der Idee her uralt, der Gesetzgeber muss systematische Tests nur durchsetzen.
25 Jahre WTO - Neuaufstellung dringend erforderlich
Authors: Häuser Wolfgang
Published: June 2020

Die WTO ist eine der zentralen internationalen Organisationen für grenzüberschreitende Handels- und Wirtschaftspolitik. Sie fungiert auch als zentrale Statistikbehörde für den Welthandel und Handelskonflikte. Das 25-Jahre-Jubiläum wird aber von zunehmenden politischen Spannungen und Handelskonflikten überschattet, die maßgeblich auf die „America first“-Politik von US-Präsident Trump zurückzuführen sind. Dieses veränderte internationale Umfeld lähmt die WTO mittlerweile immer mehr und lässt eine Neuaufstellung unausweichlich erscheinen.
Bewertung von Renditeimmobilien mit normierten und nicht normierten Verfahren
Authors: Korzmann Maximilian A. , Knuth Antonia
Published: June 2020

Die Fallstudie behandelt die Bewertung von Renditeimmobilien mit dem Ertragswertverfahren nach ImmoWertV als normiertem Verfahren sowie mit dem Discounted-Cashflow-Verfahren und der Methode des Vollständigen Finanzplans. Alle Verfahren werden am identischen Investitionsobjekt angewandt, so dass die Bewertungsergebnisse verglichen und auf ihre Sensitivität gegenüber Parameteränderungen untersucht werden können.
Nichtfinanzielle Berichterstattung
Authors: Baumüller Josef , Follert Florian
Published: June 2020

Bestimmte große Unternehmen waren für das Geschäftsjahr 2017 erstmalig verpflichtet, über ihre Nachhaltigkeitsleistung in Form einer nichtfinanziellen Berichterstattung Rechnung zu legen. Dadurch erfolgte eine Erweiterung des bisherigen Verständnisses der Unternehmensberichterstattung. Dem Nutzen einer vollständigen Abbildung des Unternehmenserfolges und seiner Auswirkungen stehen praktisch große Herausforderungen in der Umsetzung gegenüber.
Die Grundrente - Antwort auf ihre Kritiker
Authors: Mackscheidt Klaus
Published: June 2020

Ob man eine Grundrente einführen soll, wurde in Deutschland sehr lange kontrovers diskutiert. Mit der Begrenzung auf 33 Jahre und lediglich der Einkommensprüfung hat man in 2019 einen Kompromiss gefunden. Dennoch verbleiben ernst zu nehmende Einwände, die in diesem Beitrag detailliert entkräftet werden.
Handelsrechtliche Rückstellungen für ungewisse Verbindlichkeiten - Der Dieselgate-Skandal
Authors: Rade Katja , Schöning Stephan
Published: June 2020

Gemäß § 249 Abs. 1 S. 1 HGB sind Rückstellungen für ungewisse Verbindlichkeiten zu passivieren. Ungewisse Verbindlichkeiten sind solche, die im Hinblick auf Grund, Höhe und/oder Zeitpunkt der Geltendmachung mit Unwägbarkeiten behaftet sind. Es stellt sich indes die Frage: Wann sollen in welcher Höhe Rückstellungen zulasten des laufenden Gewinns, eines Gewinnvortrags oder freier Rücklagen gebildet werden? Erschwert wird die Antwort auf die Frage dadurch, dass die handelsrechtliche Rückstellungsbildung maßgeblich von der steuerrechtlichen Gesetzgebung und Rechtsprechung beeinflusst wird. Dies lässt sich beispielhaft anhand der aktuellen Situation der Volkswagen AG verdeutlichen.
Managing Customer Success in Business Markets: Conceptual Foundation and Practical Application
Authors: Eggert Andreas , Ulaga Wolfgang , Gehring Anna
Published: June 2020

Customer success management is gaining momentum in business markets. From an initial focus on selected industries, such as software-as-a-service, interest in customer success is spreading among business-to-business marketing practitioners. To date, academia has largely neglected this concept and its organizational implementation. Based on extant managerial literature and research on value in use in business markets, we distinguish between customer success as a customer-perceived construct, customer success management as a joint customer-supplier management process, and the emerging job position of customer success managers in supplier organizations. Based on the case of a provider of IoT devices, software and services in decision agriculture, we illustrate how customer success management is practiced in a business marketing context and refine our understanding of customer success management and its constituents. Finally, we suggest promising avenues for future research in this managerially important, under-researched and rapidly growing domain.
From Muso to Academic and Back: A Time and Person-Based Acknowledgement of Michael Kleinaltenkamp
Authors: Karpen Ingo , Plewa Carolin
Published: June 2020

The year 2020 sees an important milestone for Professor Michael Kleinaltenkamp (Michael hereafter), as he concludes his official academic working life. This paper acknowledges the significant contribution Michael has made over the years. In particular, using Leximancer to undertake textmining of Michael’s English language publications, we not only uncover the underlying structure of these contributions but also explore if and how focal themes of his research have changed, particularly considering his close engagement with the Australasian academic marketing community. Findings indicate foundational facets and the overall gestalt of his research over time, yet also point to important differences across the time periods analysed. Finally, we reflect on our findings from a musical perspective, drawing on Michael’s passion for music, as we thank him for the many jams and the rehearsing, aswell as for his support for the bands and scenes he belongs to. For future research, it should be noted that future acknowledgements would benefit from cooking as a metaphor to complete the picture.
Specific dimensions of leadership in project management
Authors: Djhelilova Rezmie , Islam Atche
Published: June 2020

The report focuses on some specific dimensions of leadership in project management. Consideration is given to a set of factors that influence effective leadership in the project team. It is pointed out that in an environment of uncertainty and complexity, more and more organizations are moving towards a team approach for implementing project activities, thus striving to overcome the challenges of the environment in which they operate. In project management, leadership must take into account the current situation of the organization implementing the project. The most important task of the leaders in the field of project management is to achieve results. Leadership in project management can also be seen as a function of circumstance and the result of the interaction between members of the team who appoint a representative to organise a project and achieve its objectives.
Aspects of conflicts within the organization
Authors: Georgieva Ivona , Georgieva Slavka
Published: June 2020

The article focuses on some of the aspects of conflicts within the organization. Issues leading to conflicts are discussed as an integral part of organizational life. The main types of conflicts are characterized. It is emphasized that regardless of the outcome of the conflict, its consequences have a certain impact and that each organization could benefit even from the conflict. There is no universal way of correct resolution, it depends on the conflict itself, the individual characteristics of each of the team members and, above all, the correct approach of the leaders. Failure to listen and downplaying the other side does not solve the problem. The best way out of conflict is solving the problem that caused the conflict.
The intersection of cultural dimensions, social media usage and consumer purchase intention
Authors: Juršė Andrėja , Makackaitė Aistė , Jakutytė Gabija , Kievišienė Laura
Published: June 2020

The role of social media in today’s life is almost imperative. Social media platforms, such as Facebook, Instagram or Youtube are widely used all over the world. Above all, social media has become a global phenomenon, which has dramatically changed the concept of cross-cultural communication not only between individuals, but also brands and consumers. Varieties of social media platforms provide a new channel to acquire information through peer communication, thus influencing consumer purchase intention. Although diverse cultures have different cultural backgrounds, they affect the acceptance of social media usage. In order to broaden the understanding of this rapidly changing field, this paper provides a framework, based on Hofstede’s dimensions and Technology Acceptance model, for examining the intersection of cultural differences, social media usage and consumer behaviour to set the agenda for future research.
Internet marketing tools
Authors: Sturienė Urtė
Published: June 2020

In today's world, every business organization can pursue marketing goals online. Choosing the right Internet marketing tools or combining several may be significant in reaching the target audience. Therefore, without precise criteria for assessing the impact of Internet marketing tools on business organizations, it is not very easy to choose the most appropriate tools to compete with other businesses. This paper aims to investigate the impact of Internet marketing tools on business organizations. In order to achieve this goal, the following tasks are set: to analyse the Internet marketing concept and to reveal the impact assessment criteria. The results have shown that there is no agreed scientific definition of the term and concept of Internet marketing tools. However, it is obvious that Internet marketing is the part of digital marketing. Also, the Internet marketing impact criteria consist of short-term effect, long-term effect, and alternatives. Internet marketing tools typically drive sales growth, strengthen the brand and help to build and maintain relationships with clients.
The impact of logistics sector on sustainable development
Authors: Šulskytė Deimantė
Published: June 2020

In the context of global economy, logistics activities are necessary for ensuring the global competitiveness of other sectors and comprehensive development of the country. In the recent years, the concept of sustainable development is changing the meaning of economic growth. Taking into account the meaning of logistics and principles of sustainable development, the main aim of the article is to assess the impact of the logistics sector on sustainable development. In order to achieve this aim, theoretical concepts of sustainable development, logistics and its relationship are revealed , as well as key macroeconomic indicators and indices are identified and applied when evaluating the impact of logistics sector on sustainable development. The findings indicate that in the context of European Union countries, logistics sectors related with transport and IT factors significantly influence different indices of sustainable development.
Morphology Features of the Suffixal Slang Adverbs in the Lithuanian Language: Hybrid Suffixcal Derivatives -ai formed from the Suffixal Adjectives -iškas and from the Primary Adjectives
Authors: Kudirka Robertas
Published: June 2020

This article is one part of the research of adverbs in Lithuanian slang. Although there is no systematic and comprehensive research into the Lithuanian language slang, slang is commonly believed to be chaotic and have no grammatical system. The purpose of this article is to morphologically examine the derivatives formed with suffix -ai from the adjectives with suffix -iškas and from the primary adjectives without suffixes. The material (79 adverbs) is collected from the dictionary of Lithuanian slang and the dictionary of non-standard Lithuanian. The study aims to identify the systematic morphological features. To achieve the aim the research words are classified according to their suffixes, their origin is determined and morphological analysis is performed.The research reveals that a foreign language unit that emerges in the context of another language undergoes assimilation - it is transformed in one way or another by adapting it to the linguistic system. In Lithuanian slang, adverbs with the suffix -ai are mostly made up from hybrid adjectives of Russian origin with the suffix -iškas. There is also a number of adverbs formed from English hybrid adjectives. A few are derived from semantically neologic adjectives. The majority of suffixal -ai derivatives that are formed from primary adjectives are Russian origin. Adverbs which are derived from the adjectives with the suffix -iškas always retain the accent in the root: this pattern is common to all slang adverbs. All forms of adverbial degrees have accented suffixes. The findings of the reseach reveal that the morphological features of the studied slang adverbs have undergone certain transformations and follow the regularities of the Lithuanian language system: the slang adverbs copy derivative models of the standard language.
Limitaciones de la lectura de la temperatura temporal (en la frente) como método de tamizaje para el Covid-19
Authors: Aragón-Vargas Luis Fernando
Published: June 2020

Conforme continúa la evolución de la pandemia por Covid-19, muchos países inician el proceso de reapertura de escuelas, iglesias y negocios. En un esfuerzo de tamizaje para detectar personas potencialmente infectadas, cada día se les está midiendo la temperatura de la arteria temporal (en la frente) a miles de personas. En este editorial se plantean algunas de las limitaciones principales de este procedimiento como método de tamizaje para Covid-19 y se advierte acerca del peligro de caer en una falsa sensación de seguridad, causada por esa práctica.
Pengaruh Paramater Lingkungan Terhadap Kepadatan Makroalga di Pesisir Kei Kecil, Maluku Tenggara
Authors: Silaban Rosita , Kadmaer E. M. Y.
Published: June 2020

Kualitas perairan merupakan salah satu faktor yang berpengaruh terhadap pertumbuhan dan perkembangan makroalga. Penelitian ini bertujuan untuk mengkaji tentang jenis makroalga, kepadatan makroalga dan pengaruh kualitas perairan terhadap kepadatan makroalga di perairan Kei Kecil, Kabupaten Maluku Tenggara. Perairan Kei Kecil memiliki 53 spesies makroalga dengan nilai kepadatan tertinggi di Desa Tanimbar, selanjutnya Ur Pulau dan Uf yang masing-masing sebesar sebesar Kei 363 ind/ m2,308 ind/m2 dan 298 ind/m2. Hubungan antara parameter fisika-kimia dengan kepadatan makroalga dianalisis menggunakan regresi linier berganda. Parameter fisika-kimia memberikan karakteristik yang berbeda antara kedua lokasi penelitian (kecamatan Kei Kecil Barat dan Kei Kecil Timur Selatan). Adapun kepadatan makroalga di kecamatan Kei Kecil Barat dapat diramalkan menggunakan persamaan (R = 98.6%) : Kepadatan = -17185.5 + 402.5 suhu + 161.7 salinitas + 3087.4 pH + 8.2 DO + 149.9 kecerahan + 5.4 kecepatan arus. Sedangkan kepadatan makroalga di kecamatan Kei Kecil Timur Selatan dapat diramalkan menggunakan persamaan (R = 76.7 %) : Kepadatan = 4794.8 – 189.4 suhu + 22 salinitas – 71.5 pH + 331.3 DO -279.9 kecerahan = 112.4 kecepatan arus. Parameter lingkungan yang mempengaruhi kepadatan makroalga yaitu suhu, salinitas, pH dan kecerahan di Kecamatan Kei Kecil Barat sedangkan salinitas, DO dan kecepatan arus di Kecamatan Kei Kecil Timur Selatan.
Analisa Kinerja Sistem Refrigerasi Berdasarkan Beban Pendinginan Ruang Pembekuan Pada Kapal Penampung Ikan
Authors: Pujianto Andreas , Latif A. M. Zaki , Septiandi Wempi
Published: June 2020

Kapal penampung ikan adalah salah satu jenis kapal perikanan. Sistem refrigerasi kompresi uap banyak digunakan pada kapal perikanan. Beban pendinginan merupakan benda-benda sumber energi panas yang dapat mempengaruhi kapasitas sistem refrigerasi. Tujuan peneliitian ini adalah menganalisa koefisien prestasi berdasarkan beban pendinginan di ruang pembekuan kapal penampung ikan 150 GT. Studi kasus dilakukan pada KM. Mina Anugrah 8 dengan pengambilan data selama 30 hari proses pembekuan. Beban pendinginan merupakan beban total dari produk maupun non produk. Coefficient of Perfomance (COP) merupakan pembagian antara kapasitas refrigerasi dengan kerja kompresi. Analisa data dilakukan untuk penggunaan 1 maupun 2 ruang pembekuan selama proses pembekuan. Nilai COP sistem refrigerasi cenderung turun dengan naiknya beban pendinginan pada ruang pembekuan. COP untuk penggunaan ruang pembekuan No.1 dengan beban pendinginan terbesar 35,45 kW adalah 2,63. COP untuk penggunaan ruang pembekuan No.2 dengan beban pendinginan 23,05 kW adalah 2,69. Sedangkan untuk penggunaan dua ruang pembekuan dengan beban pendinginan 75,6 kW adalah 2,48.
PENGEMBANGAN DESAIN PERANGKAT AIS UNTUK NELAYAN TRADISIONAL
Authors: Kuncoro Ari , Ma'muri Ma'muri , Agus Muhammad
Published: June 2020

Nelayan tradisional beroperasi menggunakan perahu berpenggerak mesin dan dayung dengan kapasitas dibawah 5 GT, tanpa dilengkapi peralatan pelayaran untuk komunikasi dan navigasi. Permasalahan timbul ketika terjadi kecelakaan laut yang menimpa nelayan, akan kesulitan untuk dilakukan pencarian atau pertolongan. KKP bersama Labs247 pada tahun 2017 membuat perangkat navigasi yaitu alat Pemantauan Kapal Berbasis AIS, alat ini seperti perangkat mobile yang digunakan diperahu nelayan tradisional untuk diawasi oleh pihak pengawas lalu lintas laut. Namun alat Pemantauan Kapal Berbasis AIS dirasa kurang kecil dan kompak serta tidak adanya socket untuk me-recharge baterai. Tujuan penelitian untuk mendesain ulang alat Pemantauan Kapal Berbasis AIS dengan membuat desain casing baru dan desain bracket untuk meletakkan perangkat Pemantauan Nelayan Berbasis AIS yang disingkat PELAYAR’S. Metode menggunakan analisis deskriptif melalui pengambilan data dilapangan dan internet yang dilanjutkan dengan membuat desain perangkat PELAYAR’S dengan menggunakan AutoCAD 2014  dan Sketch-up 2014. Dari penelitian dihasilkan desain casing dengan volume 3000 cm3 disertai socket untuk me-recharge baterai, serta desain bracket. Setelah desain perangkat PELAYAR’S ini jadi, tahap selanjutnya akan dibuat prototipe agar dapat dipakai nelayan tradisional saat melaut. Pemakaian perangkat PELAYAR’S akan mempermudah pengawasan nelayan tradisional dilaut, sehingga saat terjadi kondisi darurat nelayan tradisional dapat menggunakan perangkat PELAYAR’S untuk meminta pertolongan.
Embedding the weighted space $Hv_0(G, E)$ of holomorphic functions into the sequence space $c_0(E)$
Authors: El Abbassi El Mustapha , OUBBI Lahbib
Published: June 2020

We embed almost isometrically the generalized weighted space $Hv_0(G, E)$ of holomorphic functions on an open subset $G$ of $\mathbb{C}^N$ with values in a Banach space $E$, into $c_0(E)$, the space of all null sequences in $E$, where $v$ is an operator-valued continuous function on $G$ vanishing nowhere. This extends and generalizes some known results in the literature. We then deduce the non 1-Hyers-Rassias stability of the isometry functional equation in the framework of Banach spaces.
Epistemic Integrity Constraints for Ontology-Based Data Management
Authors: Console Marco , Lenzerini Maurizio
Published: June 2020

Ontology-based data management (OBDM) is a powerful knowledge-oriented paradigm for managing data spread over multiple heterogeneous sources. In OBDM, the data sources of an information system are handled through the reconciled view provided by an ontology, i.e., the conceptualization of the underlying domain of interest expressed in some formal language. In any information systems where the basic knowledge resides in data sources, it is of paramount importance to specify the acceptable states of such information. Usually, this is done via integrity constraints, i.e., requirements that the data must satisfy formally expressed in some specific language. However, while the semantics of integrity constraints are clear in the context of databases, the presence of inferred information, typical of OBDM systems, considerably complicates the matter. In this paper, we establish a novel framework for integrity constraints in the OBDM scenarios, based on the notion of knowledge state of the information system. For integrity constraints in this framework, we define a language based on epistemic logic, and study decidability and complexity of both checking satisfaction and performing different forms of static analysis on them.
Complexity and Expressive Power of Disjunction and Negation in Limit Datalog
Authors: Kaminski Mark , Cuenca Grau Bernardo , Kostylev Egor V. , Horrocks Ian
Published: June 2020

Limit Datalog is a fragment of Datalogℤ—the extension of Datalog with arithmetic functions over the integers—which has been proposed as a declarative language suitable for capturing data analysis tasks. In limit Datalog programs, all intensional predicates with a numeric argument are limit predicates that keep maximal (or minimal) bounds on numeric values. Furthermore, to ensure decidability of reasoning, limit Datalog imposes a linearity condition restricting the use of multiplication in rules. In this paper, we study the complexity and expressive power of limit Datalog programs extended with disjunction in the heads of rules and non-monotonic negation under the stable model semantics. We show that allowing for unrestricted use of negation leads to undecidability of reasoning. Decidability can be restored by stratifying the use of negation over predicates carrying numeric values. We show that the resulting language is Π2EXP -complete in combined complexity and that it captures Π2P over ordered structures in the sense of descriptive complexity.We also provide a study of several fragments of this language: we show that the complexity and expressive power of the full language are already reached for disjunction-free programs; furthermore, we show that semi-positive disjunctive programs are coNEXPcomplete and that they capture coNP.
K-BERT: Enabling Language Representation with Knowledge Graph
Authors: Liu Weijie , Zhou Peng , Zhao Zhe , Wang Zhiruo , Ju Qi , Deng Haotang , Wang Ping
Published: June 2020

Pre-trained language representation models, such as BERT, capture a general language representation from large-scale corpora, but lack domain-specific knowledge. When reading a domain text, experts make inferences with relevant knowledge. For machines to achieve this capability, we propose a knowledge-enabled language representation model (K-BERT) with knowledge graphs (KGs), in which triples are injected into the sentences as domain knowledge. However, too much knowledge incorporation may divert the sentence from its correct meaning, which is called knowledge noise (KN) issue. To overcome KN, K-BERT introduces soft-position and visible matrix to limit the impact of knowledge. K-BERT can easily inject domain knowledge into the models by being equipped with a KG without pre-training by itself because it is capable of loading model parameters from the pre-trained BERT. Our investigation reveals promising results in twelve NLP tasks. Especially in domain-specific tasks (including finance, law, and medicine), K-BERT significantly outperforms BERT, which demonstrates that K-BERT is an excellent choice for solving the knowledge-driven problems that require experts.
Deciding Acceptance in Incomplete Argumentation Frameworks
Authors: Niskanen Andreas , Neugebauer Daniel , Järvisalo Matti , Rothe Jörg
Published: June 2020

Expressing incomplete knowledge in abstract argumentation frameworks (AFs) through incomplete AFs has recently received noticeable attention. However, algorithmic aspects of deciding acceptance in incomplete AFs are still under-developed. We address this current shortcoming by developing algorithms for NP-hard and coNP-hard variants of acceptance problems over incomplete AFs via harnessing Boolean satisfiability (SAT) solvers. Focusing on nonempty conflict-free or admissible sets and on stable extensions, we also provide new complexity results for a refined variant of skeptical acceptance in incomplete AFs, ranging from polynomial-time computability to hardness for the second level of the polynomial hierarchy. Furthermore, central to the proposed SAT-based counterexample-guided abstraction refinement approach for the second-level problem variants, we establish conditions for redundant atomic changes to incomplete AFs from the perspective of preserving extensions. We show empirically that the resulting SAT-based approach for incomplete AFs scales at least as well as existing SAT-based approaches to deciding acceptance in AFs.
Learning Query Inseparable εℒℋ Ontologies
Authors: Ozaki Ana , Persia Cosimo , Mazzullo Andrea
Published: June 2020

We investigate the complexity of learning query inseparable εℒℋ ontologies in a variant of Angluin's exact learning model. Given a fixed data instance A* and a query language
On the Expressivity of ASK Queries in SPARQL
Authors: Zhang Xiaowang , Bussche Jan Van den , Wang Kewen , Zhang Heng , Yang Xuanxing , Feng Zhiyong
Published: June 2020

As a major query type in SPARQL, ASK queries are boolean queries and have found applications in several domains such as semantic SPARQL optimization. This paper is a first systematic study of the relative expressive power of various fragments of ASK queries in SPARQL. Among many new results, a surprising one is that the operator UNION is redundant for ASK queries. The results in this paper as a whole paint a rich picture for the expressivity of fragments of ASK queries with the four basic operators of SPARQL 1.0 possibly together with a negation. The work in this paper provides a guideline for future SPARQL query optimization and implementation.
Deciding the Loosely Guarded Fragment and Querying Its Horn Fragment Using Resolution
Authors: Zheng Sen , Schmidt Renate
Published: June 2020

We consider the following query answering problem: Given a Boolean conjunctive query and a theory in the Horn loosely guarded fragment, the aim is to determine whether the query is entailed by the theory. In this paper, we present a resolution decision procedure for the loosely guarded fragment, and use such a procedure to answer Boolean conjunctive queries against the Horn loosely guarded fragment. The Horn loosely guarded fragment subsumes classes of rules that are prevalent in ontology-based query answering, such as Horn ALCHOI and guarded existential rules. Additionally, we identify star queries and cloud queries, which using our procedure, can be answered against the loosely guarded fragment.
Piezocone penetration test-based site characterisation of Chong–Qi Bridge project, China
Authors: Liu Songyu , Zou Haifeng , Cai Guojun , Zhang Limin , Puppala Anand J
Published: June 2020

The piezocone penetration test (CPTU) provides an advanced way of characterising soil deposits in routine site investigation. This paper presents a synthesised application of CPTU in the site characterisation of Chongming–Qidong Bridge project in China, including soil classification, soil property evaluation and pile capacity estimation. Sixteen CPTU soundings and 31 borehole drillings were performed at the testing site, and their results were compared. Four CPTU-based soil classification charts were used to determine the soil types at the testing site, and their accuracy is discussed. Formulas for predicting the overconsolidation ratio and undrained shear strength of soft soils at the testing site were analysed. Six existing CPTU-based methods for assessing the ultimate capacity values of axially loaded piles were evaluated based on a database containing 14 pile load tests collected at the testing site. Practical recommendations for and implications of the use of the CPTU technique in deep-foundation projects are finally summarised.
Briefing: UK port infrastructure failures and smarter solutions
Authors: Tresidder David
Published: June 2020

Much of the UK’s ageing port infrastructure is at a tipping point, and there appears to be a recent increase in significant failures. Historically, substantially empirical design by trial and error and the inherent overdesign that this produces, combined with the use of robust materials, mean that eighteenth-and nineteenth-century port structures have sometimes lasted well. Without change in use or reduction in maintenance, they may continue to perform well. However, with the widespread use of reinforced concrete and steel sheet piles starting c. 100 years ago, the introduction of the concept of ‘design life’ was necessary. The structural ability and cost-effectiveness of maintenance of these more sensitive structures steadily decrease as the maritime degradation processes take hold. This paper considers the ever-increasing risk of infrastructure failure that the UK port industry faces and suggests the need for a considered and smart approach to the ongoing monitoring and maintenance of port assets. Examples of smart, real-time, remote monitoring technologies are discussed as the tools for port owners to avoid costly, and potentially uninsured, infrastructure failures.
Accident scenario modelling with hazardous materials in transportation infrastructures
Authors: Reis Johnny , Ribeiro Carlos , Rodrigues Daniel , Rodrigues André
Published: June 2020

The development and well-being of industrialised societies require constant coexistence with hazardous materials. These can be found in different physical states, under very different conditions of pressure and temperature, stored inside industrial units and commercial spaces with different characteristics, in the most varied conventional means of communication or in transport conduits deployed throughout the territory, greatly contributing to the territorial dispersion of these substances. This study focused on Mortágua Municipality, which is in the Central Region of Portugal. To develop this work, the authors analysed the infrastructures that support the transport of dangerous substances, the types of dangerous substances that circulate and how frequently they are transported. Then, the Aloha software was used to simulate the occurrence of an accident in each infrastructure, motivating three different analyses: the propagation of a toxic cloud, a flammable cloud and thermal radiation caused by a boiling liquid expanding vapour explosion or jet fire. The results obtained show a lack of information on some of the types of transport for these dangerous substances, and when these data exist, they are not properly handled. However, it can be concluded that if an accident occurs in the presented municipality, the socio-economic losses will be very high.
Battlespace Next(TM)
Authors: Flack Nathaniel , Lin Alan , Peterson Gilbert , Reith Mark
Published: June 2020

Changes in the geopolitical landscape and increasing technological complexity have prompted the U.S. Military to coin the terms Multi-Domain Operations (MDO) and Joint All-Domain Command and Control (JADC2) as over-arching strategy to frame the complexity of warfare across both traditional and emerging warfighting domains. Teaching new concepts associated with these terms requires both innovation as well as distinct education and training tools in order to realize the cultural change advocated by senior military leaders. Battlespace NextTM (BSN) is a serious game designed to teach concepts integral to MDO and initiate discussion on military strategy while conserving time, money, and manpower. BSN, a Collectable Card Game (CCG), is engineered to provide an engaging learning tool that educates on capabilities in a multi-domain conflict. This paper proposes an extensible game framework for modeling and reasoning about MDO concepts and presents our empirical feedback from over 120 military play testers evaluating a moderate to difficult version of the game. Results reveal the game teaches MDO concepts and delivers an engaging, hands-on learning experience. Specifically, we provide evidence it improved military readiness in seven areas of MDO in at least 62% of participants and 76% of respondents reported they enjoyed playing the game.
High-molecular weight DNA extraction and small fragment removal ofAscochyta lentis v1
Authors: Wolfram JWD Debler Johannes , Jones Ashley , Nagar Ramawatar , Sharp Anna , Schwessinger Benjamin
Published: June 2020

Extracting pure high-molecular weight DNA from some fungal species is difficult due to the presence of polysaccharides and potentially other compounds which biochemically mimic DNA or interfere with the DNA extraction process. Such compounds can co-elute with DNA in many extraction methods, being difficult to separate fom the DNA. Although the contaminant may not be detected by spectrophotometers or fluorometric devices, it substantially interferes with long-read DNA sequencing, such as Oxford Nanopore Technologies. To partially resolve this, a protocol is presented with some updates to current strategies and incorporates a small fragment removal step using Polyethylene Glycol. Using this protocol, we have been successfully sequencing the lentil pathogen Ascochyta lentis with a MinION (Oxford Nanopore Technologies). Sequencing yields have surpassed 13 gigabases with an N50 of approximately 15 kb. To increase sequencing output, more work is needed to identify and remove the elusive contaminants. DNA extraction modified from: https://www.protocols.io/view/high-molecular-weight-dna-extraction-from-challeng-5isg4ee PEG small fragment elimination after: https://www.protocols.io/view/size-selective-precipitation-of-dna-using-peg-amp-7erhjd6
Formación de trampas extracelulares de neutrófilos humanos In vitro: descripción de un método
Authors: Pérez Zapata Lizet Jazmín , Trejos Ramírez Ana María , Arias Sierra Andrés Augusto , López Quntero Juan Álvaro
Published: June 2020

INTRODUCCIÓN: las trampas extracelulares de neutrófilo (NETs) son estructuras en forma de red compuestas de ADN y proteínas granulares que el neutrófilo libera al espacio extracelular en respuesta a diferentes estímulos. La NETosis es un mecanismo de muerte celular, que además cumple una función microbicida destruyendo o inhibiendo el crecimiento de microorganismos.OBJETIVO: describir el proceso para inducir, visualizar y cuantificar la formación de NETs en neutrófilos humanos.MÉTODOS: se aislaron neutrófilos de sangre periférica de individuos sanos y se indujo la producción de NETs utilizando diferentes concentraciones de PMA a determinados tiempos. La liberación de ADN se cuantificó por espectrofluorimetría y se evaluó la morfología de las NETs utilizando microscopía de fluorescencia. Los análisis estadísticos se realizaron con los programas SPSS 17.02 y GraphPad Prism 6.RESULTADOS Y CONCLUSIONES: en el presente trabajo se describe un método que sirve para inducir NETs utilizando neutrófilos humanos, el cual es comparable con otros estudios descritos en la literatura. Los resultados y técnicas descritas aquí se pueden aplicar en ensayos que busquen evaluar el proceso de formación de NETs in vitro y tiene como intensión brindar herramientas metodológicas a los investigadores que deseen estudiar este proceso celular.
Prevalencia de Anaplasma spp. en el ámbito mundial: Revisión sistemática 1978–2018
Authors: Urán Johanna , Cardona Arias Jaiberth Antonio
Published: June 2020

INTRODUCCIÓN: el objetivo de este estudio fue describir la prevalencia mundial de Anaplasma spp. y las prevalencias específicas según lugar y año de estudio, especie y técnica diagnóstica con base en investigaciones originales reportadas en la literatura científica mundial.MÉTODOS: se realizó una revisión sistemática en Medline-Pubmed y SciELO con 14 estrategias de búsqueda, siguiendo las fases de la guía PRISMA y garantizando exhaustividad y reproducibilidad. Se incluyeron 221 estudios, la mayoría publicados entre 2011 y 2015.RESULTADOS: los países con mayor número de estudios fueron Estados Unidos (n=32), China y Alemania (n=15), Polonia (n=14) y Brasil (n=12). La principal prueba diagnóstica fue la PCR (70 %). La mayor proporción de investigaciones fue en rumiantes (30,3 %), garrapatas (23,6 %) y cánidos (16,8 %), en menor proporción se estudiaron los felinos (3,2 %) y équidos (1,8 %). En los 221 estudios, la población fue de 337.119 individuos en quienes se halló una prevalencia global del 6,28 % (21.175). Las mayores prevalencias específicas se hallaron en los équidos con un 25,67 % (n=409) y los cérvidos con 21,14 % (n=6.215). La frecuencia de positivos por microscopía fue 49,4 % (n=1.747) y por PCR 10,57 % (n=90.891).CONCLUSIONES: la anaplasmosis es una enfermedad zoonótica importante por su distribución mundial, amplio rango de hospederos y vectores, su elevada prevalencia en múltiples especies y su elevado riesgo para la salud humana y animal.
La biorremediación en Colombia y sus aplicaciones
Authors: Rosero-Garcia Doris Amanda
Published: June 2020

Introducción: la biodiversidad se está viendo afectada por la contaminación del suelo, el aire y el agua, con el fin de buscar una solución a estos desastres existen técnicas de biorremediación que se pueden aplicar en diferentes procesos en Colombia.  Objetivo: el objetivo de esta revisión bibliografía es recopilar todos los estudios de biorremediación en Colombia y analizar que técnicas o aplicaciones son comunes para llevar a cabo este proceso.Métodos: se realizó una búsqueda bibliográfica exhaustiva en diferentes bases de datos: ScienceDirect, Scielo, Redalyc, PubMed, EBESCO y Scopus. Se aplicaron criterios de inclusión para la selección de las publicaciones a analizar.Resultados y conclusión: La búsqueda bibliográfica arrojó un total de 1.758 resultados y para el análisis de la literatura se seleccionaron 60 artículos. Como conclusión principal se puede observar que en Colombia se comenzaron a publicar estudios relacionados con la biorremediación desde el año 2.002 y el interés por el tema incrementa cada año.
"Estructura histórica, social y política de Colombia", writen by Fernando Guillén Martínez
Authors: Robles Baez Christian
Published: June 2020

Review of the book "Historical, social and political structure of Colombia", by the historian and sociologist Fernando Guillén Martínez
Efectos de la suplementación con vitamina E en la reducción del dolor muscular de inicio retardado. Una revisión narrativa.
Authors: Fuentes-Barria Héctor , Aguilera-Eguia Raúl , González-Wong Catalina , Schramm-Saavedra Aylinne , Muñoz-Peña Denisse
Published: June 2020

Antecedentes: actualmente existe un creciente interés en investigar métodos que logren disminuir el dolor muscular de inicio retardado. Se ha postulado que antioxidantes como las vitaminas C y E pueden atenuarlo. Objetivo: evaluar la efectividad de vitamina E en la atenuación del dolor muscular de inicio retardado. Materiales y métodos: se realizó una búsqueda bibliográfica en las bases de datos Medline, Registro Central Cochrane, Scopus, SportDiscus y SciELO, utilizando los términos: “vitamin e supplementation”, “muscle damage” y “delayed onset muscle soreness”. Resultados: se revisaron estudios en diversos grupos poblacionales, con diferentes métodos de evaluación y diversas dosis de vitamina E. Los resultados obtenidos fueron controversiales, en algunos casos se demostró un efecto atenuante del dolor muscular de inicio retardado y en otros casos no. Conclusiones: la vitamina E produce una disminución del estrés oxidativo y estabilización el sarcolema; no obstante, faltan pruebas concluyentes para afirmar que la vitamina E tenga el efecto de generar mejoras en los biomarcadores asociados al dolor muscular de inicio retardado.
Forced Marriages in Europe: A Form of Gender-Based Violence and Violation of Human Rights
Authors: Barcons Campmajó María
Published: June 2020

Forced marriages are recognized as a form violating human rights, descriminatiing against women as well as a form of gender-based violence which both women and children suffer. In numerous international treaties and in other supranational documents, this practice is perceived as a violation against people’s dignity and as an attempt against fundamental rights such as freedom and equality. Moreover, the forced marriage is a crime condemned by the International and European human rights law: it violates the right to freely marry and the right to live a life free of gender-based violence. The objective of this article is to critically review the international and European obligations of States in relation to forced marriages. This critical review will be carried out through normative analysis from Legal Feminism and Feminist Theory.
Blasphemy As A Thick Concept
Authors: Pérez de la Fuente Oscar
Published: June 2020

Thick concepts have been central in metaethical debates over the last few decades, for instance in the controversy between cognitivism and non-cognitisivism or in the fact/value distinction. They are characterised as world guided, action guiding and community shared. In this paper, thick concepts are used to analyse case law on blasphemy from the European Court of Human Rights. When conducting this analysis, the test of civility proposed by Habermas and Rawls will also be applied. Public reason obligates the use of reasons accessible to all, that is to say not with a particular/thick meaning, in the public sphere.
Ideological Freedom And Related Legal Wording
Authors: Puig Hernández Marc-Abraham
Published: June 2020

In practical discourse, we can find out legal wording that is associated with ideological freedom and applied interchangeably: freedom of thought, freedom of conscience and religious freedom. In this essay, our aim consists in determining which the proper use of each expression is. For this purpose, we have observed: how the concept of ideological freedom is established in some legal systems; how it can be differentiated from religious freedom clearly but not from freedom of conscience on account of a vague material scope of validity; and why these difficulties move from conceptual to legal areas. In order to propose a convenient use to the latter expressions, we draw on BERLIN’s two concepts of liberty.
Freedom from Nuclear Weapons? IHRL And IHL Perspective vs the State-Centred Approach
Authors: Kapelańska-Pręgowska Julia
Published: June 2020

23 years after the ICJ’s Advisory Opinion on the Legality of the Threat or Use of Nuclear Weapons, a general treaty prohibiting the use of nuclear weapons has been adopted. It may be anticipated that the TPNW will probably not enter into force very soon, and when it does, it will neither be universally accepted, nor will it significantly influence thepractice of the nuclear weapon States. It is therefore justified to analyse the problem under consideration, not from a State-oriented perspective, but from a human and environmentally centred one. The article argues not only that any use of nuclear weapons would be contrary to the rules of international law applicable in armed conflict, in particular the principles and rules of international humanitarian law, but it would also violate international human rights law. The article further dwells upon the customary international law aspects of the problem under consideration.
New Instruments for Human Rights Protection in Globalization
Authors: Ovejero Puente Ana M.
Published: June 2020

The Ruggie principles have given new impulse to the process of developing and modernizing International Lawthrough the influence of human rights. However, this process has been developed as “soft law” measuresincluded in the corporate social responsibility activities of multinational companies, which academic opiniondeems has lessened the capacity of human rights for transforming international law into more effective and trulybinding instruments to avoid abuses against human dignity. This issue has prompted a debate concerning the roleof multinationals as subjects of international law, and the advisability of returning to more traditional andconservative approaches to governance of globalization and to effective protection of human rights from riskybusiness activities. However, thanks to Common Law traditions, this model may be transformed into binding rules,using the legal tools of private Law. This reveals the utility of such soft Law regulations in creating cultures ofrespect useful when rule of law is weak to rule relations between states, companies and people, that arise fromthe actions of private individuals rather than the activity of public law-making institutions.