bluuebunny/crossref_metadata_2025 huggingface dataset:
Influence of Temperature and Plant Growth Stages of Red Clover and Wheat on Small Broomrape (Orobanche minor) Germination
Authors: Al-Thahabi Salam A. , Colquhoun Jed B. , Mallory-Smith Carol A.
Published: February 2014

Small broomrape is a holoparasitic plant that attaches to the roots of red clover as well as several other host plants. Hosts and false hosts produce stimulants that induce small broomrape germination but small broomrape does not attach to a false host. Wheat has been identified as a false host for small broomrape; therefore, studies were conducted to investigate the effect of red clover and wheat root exudates on small broomrape germination. In one study, the effect of exudates from red clover and wheat at multiple growth stages on small broomrape germination was evaluated. Red clover induced small broomrape germination at all growth stages tested but was greatest (78%) in the presence of exudates from red clover at the three-trifoliolate stage. Maximum small broomrape germination was 25% when exposed to exudates produced by one-leaf-stage wheat. In a second study, the relationship between small broomrape germination and host growth condition was evaluated using root exudates from red clover or wheat grown under several temperature conditions for either 4 or 8 wk. For the different temperatures, there were no differences in small broomrape germination when exudates of red clover grown for 4 wk were used. Small broomrape germination was reduced when exposed to exudates from red clover plants grown for 8 wk at 10 C compared with plants grown at 15, 20, and 25 C. Differences in small broomrape seed germination were observed with temperature under which wheat was grown for 4 wk, but not for 8 wk. Although wheat exudates resulted in less small broomrape seed germination than red clover exudates, growing wheat as a false host in a small broomrape-infested field could be an important component of an integrated management plan.
‘Covington' Sweetpotato Tolerance to Flumioxazin Applied POST-Directed
Authors: Meyers Stephen L. , Jennings Katherine M. , Monks David W.
Published: February 2014

Field studies were conducted at Clinton, NC (2009, 2010), and Kinston, NC (2010), to determine ‘Covington' sweetpotato tolerance to flumioxazin applied after transplanting. Flumioxazin was directed to 25% of the sweetpotato vine beginning at the distal end (shoot tip), 25% of the vine beginning at the proximal end (crown), or to the entire vine (over-the-top) and was applied at 2 or 5 wk after transplanting (WAP). Applications made at 2 WAP resulted in 10 to 16% foliar necrosis at 3 WAP. Necrosis was transient and ≤ 2% by 6 WAP. Stunting injury at 6 WAP for flumioxazin applied at 2 WAP was greatest (12%) with the over-the-top application, followed by crown (5%), and shoot tip (1%) applications. Applications made at 5 WAP resulted in 35, 23, and 15% foliar necrosis at 6 WAP for over-the-top, crown, and shoot tip applications, respectively. By 12 WAP, stunting injury for all treatments was ≤ 3%. No. 1, jumbo, canner, and total marketable sweetpotato yield of the nontreated check was 36,670; 7,610; 7,170; and 51,450 kg ha−1, respectively. No. 1 and total marketable sweetpotato yields were reduced when flumioxazin was applied at 2 or 5 WAP. No. 1 sweetpotato yield was reduced when flumioxazin was applied to the crown or over-the-top (27,240 and 28,330 kg ha−1, respectively). Sweetpotato receiving flumioxazin applied to the shoot tip had similar no. 1 (31,770 kg ha−1) yields as the nontreated check, crown, and over-the-top applications. Total marketable sweetpotato yield was reduced by flumioxazin application to shoot tip, crown, and over-the-top (45,350; 40,100; 40,370 kg ha−1, respectively). Neither flumioxazin application timing nor placement influenced either jumbo- or canner-grade sweetpotato yields. Currently, after-transplant applications of flumioxazin do not appear to be a suitable fit for POST weed control in North Carolina sweetpotato production systems.
Purple Nutsedge Control with Allyl Isothiocyanate under Virtually Impermeable Film Mulch
Authors: Bangarwa Sanjeev K. , Norsworthy Jason K.
Published: February 2014

Nutsedge control is challenging in commercial vegetable production in the absence of methyl bromide, and therefore, an effective alternative is needed. This study investigated allyl isothiocyanate (ITC) as a methyl bromide alternative for purple nutsedge control under polyethylene-mulch. Greenhouse experiments were conducted to compare the retention of allyl ITC in treated soil (3,000 nmol g−1) under low-density polyethylene (LDPE) and virtually impermeable film (VIF) mulches. Field experiments were conducted to evaluate the effectiveness of allyl ITC (6 rates: 0, 15, 75, 150, 750, 1500 kg ai ha−1) under VIF mulch against purple nutsedge. Additionally, a standard treatment of methyl bromide+chloropicrin (67 : 33%) at 390 kg ai ha−1under LDPE mulch was included for comparison. In the greenhouse experiment, the predicted half-life of allyl ITC under LDPE and VIF mulch was 0.15 and 0.59 d, respectively. In the field experiment, it was predicted that allyl ITC at 1,240 and 1,097 kg ha−1under VIF mulch is required to control purple nutsedge shoot and tubers equivalent to methyl bromide + chloropicrin at 4 wk after treatment (WAT). It is concluded that allyl ITC under VIF mulch would need to be applied at 2.8 to 3.2 times the standard treatment of methyl bromide + chloropicrin under LDPE mulch for commercially acceptable purple nutsedge control.
Dissipation of Pendimethalin in Organic Soils in Florida
Authors: Odero Dennis C. , Shaner Dale L.
Published: February 2014

Understanding the persistence of PRE-applied pendimethalin is important in determining timing of subsequent weed management programs in sugarcane on organic soils in the Everglades Agricultural Area (EAA). Dissipation of oil- and water-based pendimethalin formulations applied PRE at 2, 4, and 8 kg ai ha−1were compared in 2011 and 2012 on organic soils in the EAA. The rate of dissipation of both formulations was very similar. Both formulations had an initial rapid rate of dissipation followed by a slower rate of dissipation. However, the initial amount of pendimethalin in the soil was higher with the water-based compared to the oil-based formulation, most likely because of the lower volatility of the water-based formulation. The half-lives (DT50s) of the oil-based formulation were 32, 18, and 10 d and 8, 8, and 12 d at 2, 4, and 8 kg ha−1, respectively, in 2011 and 2012, respectively. The DT50s of the water-based formulation were 20, 13, and 10 d and 12, 12, and 14 d at 2, 4, and 8 kg ha−1, respectively in 2011 and 2012, respectively. These DT50values were attributed to low soil water content as well as the absence of incorporation following application. Our results suggest that dissipation of pendimethalin is rapid on organic soils irrespective of the formulation when applied under dry soil conditions with no incorporation into the soil.
Johnsongrass (Sorghum halepense) Management as Influenced by Herbicide Selection and Application Timing
Authors: Johnson Dennis B. , Norsworthy Jason K.
Published: February 2014

Field experiments were conducted in 2009 and 2012 at Fayetteville, AR, to compare four herbicides across three application timings for johnsongrass control and to evaluate the effect of late-season herbicide applications on johnsongrass control, fecundity, seed viability, and progeny emergence. In the first experiment, glyphosate at 840 g ae ha−1and clethodim at 68 and 136 g ai ha−1provided 75 to 94% control of 15- to 60-cm tall johnsongrass and up to 98% stand reduction 4 wk after treatment (WAT). Glufosinate and nicosulfuron were generally effective on ≤30-cm tall johnsongrass; however, efficacy declined as johnsongrass size increased. In the second experiment, glyphosate at 840 g ha−1provided at least 89% johnsongrass control when applied at boot or after panicle emergence and up to 95% stand reduction 3 WAT. Applications of glyphosate at 420 and 840 g ha−1, clethodim at 68 and 136 g ha−1, and glufosinate at 740 g ai ha−1at the boot stage reduced viable seed production of treated plants 94 to 99%. Irrespective of rate, glyphosate and clethodim applied at boot stage reduced progeny emergence by 77 to 95% and 100-seed weight of treated plants 62 to 96% compared to the nontreated check. This research demonstrates the importance of herbicide selection, particularly for controlling johnsongrass plants larger than 30 cm. Additionally, the results demonstrate the benefits of a single application of glyphosate or clethodim at the boot stage of johnsongrass for decreasing the soil seedbank and reducing the success of johnsongrass progeny in future years.
Modeling the Simultaneous Evolution of Resistance to ALS- and ACCase-Inhibiting Herbicides in Barnyardgrass (Echinochloa crus-galli) in Clearfield®Rice
Authors: Bagavathiannan Muthukumar V. , Norsworthy Jason K. , Smith Kenneth L. , Neve Paul
Published: February 2014

Herbicide-resistant barnyardgrass has become widespread in the rice production systems of the midsouthern United States, leaving few effective herbicide options for controlling this weed. The acetolactate synthase (ALS)- and acetyl-CoA carboxylase (ACCase)-inhibiting herbicides remain largely effective in Clearfield®rice production, but strategies need to be developed to protect the long-term utility of these options. A two-trait model was developed to understand simultaneous evolution of resistance in barnyardgrass to the ALS- and ACCase-inhibiting herbicides in Clearfield rice. The model was used to predict resistance under a number of common weed management scenarios across 1,000 hypothetical rice fields in the Mississippi Delta region and answer some key management questions. Under an ALS inhibitor–only program consisting of three annual applications of imidazolinone herbicides (imazethapyr or imazamox) in continuous Clearfield rice, resistance was predicted within 4 yr with 80% risk by year 30. Weed management programs that consisted of ALS- and ACCase-inhibiting herbicides such as fenoxaprop and cyhalofop greatly reduced the risk of ALS-inhibiting herbicide resistance (12% risk by year 30), but there was a considerable risk for ACCase resistance (evolving by year 14 with 13% risk by year 30) and multiple resistance (evolving by year 16 with 11% risk by year 30) to both of these mechanisms of action. A unique insight was that failure to stop using a herbicide soon after resistance evolution can accelerate resistance to the subsequent herbicide option. Further, a strong emphasis on minimizing seedbank size is vital for any successful weed management strategy. Results also demonstrated that diversifying management options is not just adequate, but diversity combined with timely herbicide applications aimed at achieving high efficacy levels possible is imperative.
Simulated Glyphosate Drift to Potato Mother Plants and Effect on Daughter Tubers Used for Seed Production
Authors: Hatterman-Valenti Harlene M.
Published: February 2014

Field trials were conducted to evaluate the effect of simulated glyphosate drift rates applied to two non-irrigated potato cultivars in the late tuber bulking stage grown for potato seed production. Mother plants receiving a sublethal glyphosate application had similar yields regardless of the year or cultivar. ‘Red LaSoda' seed pieces visually evaluated the following spring had more sprout inhibition from glyphosate-treated plots. With ‘Russet Burbank', only seed pieces from mother plants that received more than 18 g ha−1 glyphosate showed sprout inhibition. Total yield reductions the year following glyphosate treatments were attributed to fewer and smaller tubers from plants that did not emerge or were delayed in emergence. Red LaSoda seed pieces from mother plants receiving ≥ 71 g ha−1 glyphosate yielded less than the nontreated. In 2005, Russet Burbank seed pieces from mother plants receiving ≥35 g ha−1 glyphosate had reduced yields, whereas in 2006, all glyphosate treatments reduced total yield compared with the nontreated.
Response of Seven Weed Species to Corn Gluten Meal and White Mustard (Sinapis alba) Seed Meal Rates
Authors: Yu Jialin , Morishita Don W.
Published: February 2014

Corn gluten meal (CGM) and white mustard seed meal (MSM) can release biologically active allelochemicals and have been demonstrated to be useful as PRE alternative weed control products. The objective of this study was to compare the effects of CGM and MSM on the emergence and aboveground dry weight of five broadleaf and two grass weed species. Greenhouse experiments were conducted using 26 by 53 cm plastic trays filled with a mix of field soil and potting soil (4 : 1 by wt). CGM and MSM were mixed with 1.5 kg of soil mix and applied at rates equivalent to 2,240, 4,480, and 6,720 kg ha−1. Overall, MSM was more effective than CGM for controlling weeds. Averaged over application rates and compared to the nontreated control, emergence rates were 17, 27, and 34% for kochia, common lambsquarters, and barnyardgrass, respectively, in CGM-amended soil, and 14, 13, and 6% for kochia, common lambsquarters, and barnyardgrass, respectively, in MSM-amended soil. Averaged over application rates, green foxtail and common lambsquarters aboveground dry biomass were 40 and 25% of the nontreated control, respectively, in CGM-amended soil. Green foxtail and common lambsquarters shoot biomass in MSM-amended soil was 13 and 5% of the nontreated control, respectively. Significant interactions were observed for meal by rate on redroot pigweed seedling emergence and redroot pigweed, barnyardgrass (Moscow), and annual sowthistle (Moscow) aboveground dry biomass. These interactions can be attributed to the fact that herbicidal effects were less evident in response to higher application rates using MSM compared to higher CGM application rates. Overall, this greenhouse study indicates MSM is more effective than or at least equal to CGM for broadleaf and grass weed control at the same application rate.
Structural-grade concrete containing FBC and PCC residues. Part II: Partial-cement concrete
Authors: Ghafoori Nader , Najimi Meysam
Published: February 2014

Part I of this study focused on the fresh and hardened properties of different non-cement concretes containing pulverised coal combustion (PCC) fly ash and fluidised bed combustion (FBC) spent bed in order to ascertain their capabilities and drawbacks in the production of structural-grade concrete. While these mixtures produced sufficient structural strength, their long setting times and excessive soaked sulfate-induced expansions posed major limitations on their acceptability as viable construction materials. In order to mitigate these concerns, Part II of the study, presented here, evaluates the characteristics of a number of partial-cement concretes in comparison with those of non-cement and a reference (control) Portland cement concrete. The test results revealed that the two abovementioned concerns were eliminated with proper mixture proportioning of partial-cement concretes. It was found that while early-age compressive strengths of partial-cement concretes were lower than those of the reference concrete, late strengths exceeded those of the reference concrete. Their plastic and drying shrinkages were also lower than those of the reference concrete. The studied partial-cement concretes also displayed resistance to abrasion superior to that of the reference concrete under dry conditions, whereas the opposite results were obtained under wet conditions.
Variable wind, pack ice, and prey dispersion affect the long‐term adequacy of protected areas for an Arctic sea duck
Authors: Lovvorn James R. , Anderson Eric M. , Rocha Aariel R. , Larned William W. , Grebmeier Jacqueline M. , Cooper Lee W. , Kolts Jason M. , North Christopher A.
Published: February 2014

With changing climate, delineation of protected areas for sensitive species must account for long‐term variability and geographic shifts of key habitat elements. Projecting the future adequacy of protected areas requires knowing major factors that drive such changes, and how readily the animals adjust to altered resources. In the Arctic, the viability of habitats for marine birds and mammals often depends on sea ice to dissipate storm waves and provide platforms for resting. However, some wind conditions (including weak winds during extreme cold) can consolidate pack ice into cover so dense that air‐breathing divers are excluded from the better feeding areas. Spectacled Eiders (Somateria fischeri) winter among leads (openings) in pack ice in areas where densities of their bivalve prey are quite high. During winter 2009, however, prevailing winds created a large region of continuous ice with inadequate leads to allow access to areas of dense preferred prey. Stable isotope and fatty acid biomarkers indicated that, under these conditions, the eiders did not diversify their diet to include abundant non‐bivalve taxa but did add a smaller, less preferred, bivalve species. Consistent with a computer model of eider energy balance, the body fat of adult eiders in 2009 was 33–35% lower than on the same date (19 March) in 2001 when ice conditions allowed access to higher bivalve densities. Ice cover data suggest that the eiders were mostly excluded from areas of high bivalve density from January to March in about 30% of 14 winters from 1998 to 2011. Thus, even without change in total extent of ice, shifts in prevailing winds can alter the areal density of ice to reduce access to important habitats. Because changes in wind‐driven currents can also rearrange the dispersion of prey, the potential for altered wind patterns should be an important concern in projecting effects of climate change on the adequacy of marine protected areas for diving endotherms in the Arctic.
Health Issues and Health Care Expenses in Canadian Bankruptcies and Insolvencies
Authors: Himmelstein David U. , Woolhandler Steffie , Sarra Janis , Guyatt Gordon
Published: February 2014

Illness can contribute to financial problems directly, through high medical bills, and indirectly, through lost income. No previous in-depth studies have documented the role of medical problems among Canadian bankruptcy filers. We obtained the bankruptcy filings from a random sample of 5,000 debtors across Canada and mailed surveys to them seeking information about the medical antecedents of their bankruptcy. A total of 521 debtors responded (response rate of 10.4%), of whom 40.1 percent reported losing at least two weeks of work-related income because of illness or injury in the two years before their filing; 8.3 percent reported a similar income loss because of caregiving responsibilities for someone else who was ill. Although 60.1 percent of respondents reported being responsible for a medical bill within the previous two years, only 6.9 percent had bills over $5,000 (all amounts in Canadian Dollars). Prescription drugs were cited as the costliest medical expense by two-thirds of debtors reporting bills > $5,000, with dental bills cited by 22.2 percent. Universal health insurance affords Canadians protection against ruinous doctor and hospital bills. Inadequate coverage for prescription drugs and dental care, however, leaves some with unaffordable out-of-pocket costs. In addition, illness is a frequent indirect cause of bankruptcy through loss of work-related income.
“You Can't Always Get What You Want” — Linearity as the Golden Ratio of Toxicology
Authors: Bast Aalt , Hanekamp Jaap C.
Published: February 2014

Referring to the Golden Ratio (i.e. expressed in the Fibonacci sequence) in nature and art, we conclude that toxicology knows its own Golden Ration, namely linearity. The latter seems imposed on pharmaco-toxicological processes that in fact show far more complexity than simple linearity could hope to elucidate. Understanding physiological and pharmaco-toxicological processes as primarily linear is challenged in this contribution based on very straightforward principles and examples.
Chernobyl-Related Cancer and Precancerous Lesions: Incidence Increase Vs. Late Diagnostics
Authors: Jargin Sergei V.
Published: February 2014

The reported incidence of thyroid cancer in children and adolescents in Soviet Union before the Chernobyl accident was lower than in other developed countries. This is not clearly recognizable from the literature because comparisons of the high incidence figures 4 years after the accident and later have been made with those from the first years after the accident, when the registered incidence had already started to increase. Considering the low pre-accident registered incidence, there was an accumulated pool of undiagnosed thyroid tumors before the accident. The percentage of more advanced cancers, larger in size and less differentiated, was higher after the accident, when the pool of neglected cancers was diagnosed due to the screening and improved diagnostics. Some of these advanced tumors found by screening were interpreted as aggressive radiogenic cancers. The same tendency might be true also for other cancers, e.g. renal cell carcinoma. Furthermore, the screening-effect, false-positivity and registration of non-exposed patients as Chernobyl victims has obviously contributed to the registered incidence increase of malignancy.
Physiological Changes in Older Adults and Their Effect on Diabetes Treatment
Authors: Gates Brian J. , Walker Kevin M.
Published: February 2014

In Brief

Physiological changes associated with aging have the potential to affect the treatment of diabetes. However, evidence regarding treatment of diabetes in geriatric patients has been limited, especially for “oldest-old” patients. Recent research has provided greater insight into the risks and benefits of treatment, and new guidelines provide more specific information regarding treatment goals in older people with diabetes and encourage greater individualization of treatment.
Listening to Older Adults' Values and Preferences for Type 2 Diabetes Care: A Qualitative Study
Authors: Beverly Elizabeth A. , Wray Linda A. , LaCoe Cynthia L. , Gabbay Robert A.
Published: February 2014

In Brief

Individuals' values and preferences have a considerable impact on their motivation and, therefore, their willingness to follow treatment recommendations. This qualitative study aimed to describe older adults' values and preferences for type 2 diabetes care. Older adults valued an effective physician-patient treatment relationship and quality of life in their diabetes care. They preferred physicians who knew them as a person and were honest about their diabetes treatment and progression of the illness. When developing treatment plans, providers should assess the effect that treatment will likely have on older adults' health, while explicitly acknowledging their values and preferences for care as a prelude to better patient-centered care and potentially shared decision-making.
“Es como uno bomba de tiempo [It's like a time bomb]”: A Qualitative Analysis of Perceptions of Diabetes Among First-Degree Relatives of Latino Patients With Diabetes
Authors: Castro-Rivas Erida , Boutin-Foster Carla , Milan Maria , Kanna Balavenkatesh
Published: February 2014

Background. The South Bronx, a largely Latino community, has become an epicenter of the diabetes epidemic in New York City. In this community, nondiabetic first-degree relatives of people with diabetes are prime targets for intervention. Therefore, the objective of this study was to explore the knowledge of diabetes and attitudes toward health behavior modification of Latino adults who are first-degree relatives of people with diabetes.

Methods. Participants were recruited from three settings in the South Bronx (a community-based organization, a faith-based organization, and a taxi station). The Common Sense Model was used to develop focus-group items. This model provides a framework for exploring illness representations along five domains: identity, cause, consequences, timeline, and perceptions of curability. Responses were transcribed verbatim, and data analysis proceeded in the following order: data immersion, assignment of codes, grouping of key concepts to form categories, and construction of higher-order themes.

Results. Of the 115 potential participants identified, 53 were found to be eligible, and 23 of these participated in the focus group. Of these, 20 were Dominicans, 2 were Puerto Ricans, and 1 was Salvadorian. The mean age was 46.39 years, 35% were women, 61% were married, and 26% had less than a high school education. Qualitative analyses resulted in 547 codes that were grouped into 52 concepts, from which 9 categories and 4 overarching themes emerged. The dominant themes were 1) family, genetics, and culture play a major role in the etiology of diabetes; 2) being Latino and having a first-degree relative with diabetes makes getting diabetes inevitable, and, like a time bomb exploding, it is destined to happen; 3) once one develops diabetes, the physical and emotional consequences are devastating and destructive; and 4) diabetes can be “cured” through healthy eating and with insulin.

Conclusions. In this study, first-degree relatives of patients with diabetes were knowledgeable about the risks and consequences of diabetes. However, some participants felt that being Latino and having a first-degree relative with diabetes made one destined to have diabetes. Addressing this misperception through culturally tailored interventions has implications for diabetes prevention and may help to stem the diabetes epidemic in Latino communities.
Vaccine effectiveness in preventing laboratory-confirmed influenza in Navarre, Spain: 2013/14 mid-season analysis
Authors: Castilla J , Martínez-Baz I , Navascués A , Fernandez-Alonso M , Reina G , Guevara M , Chamorro J , Ortega M T , Albéniz E , Pozo F , Ezpeleta C , Primary Health Care Sentinel Network Collective , Network for Influenza Surveillance in Hospitals of Navarre Collective
Published: February 2014

We estimate mid-2013/14 season vaccine effectiveness (VE) of the influenza trivalent vaccine in Navarre, Spain. Influenza-like illness cases attended in hospital (n=431) and primary healthcare (n=344) were included. The overall adjusted VE in preventing laboratory-confirmed influenza was 24% (95% CI: ?14 to 50). The VE was 40% (95% CI: ?12 to 68) against influenza A(H1)pdm09 and 13% (95% CI: ?36 to 45) against influenza A(H3). These results suggest a moderate preventive effect against influenza A(H1)pdm09 and low protection against influenza A(H3).
John Labatt Blows In and Out of the Windy City: A Case Study in Entrepreneurship and Business Failure, 1889–1896
Authors: Bellamy Matthew
Published: February 2014

Abstract:

The Labatt brewery of London, Ontario, just 200 kilometres from the Canada–United States border, was the first Canadian brewery to attempt a strategic expansion into the United States. The paper examines the reasons why John Labatt decided to expand into the United States at the end of the nineteenth century. It analyzes both the “push” and “pull” factors that caused him to attempt to sell his ales, porters, and stouts in Chicago. The paper argues that while entrepreneurial factors played a central role in Labatt's geographic expansion into the United States, structural factors were more important as a factor in the ultimate inability of Labatt to capture a share of the Chicago market.
“No Political Significance of Any Kind”: Glenn Gould's Tour of the Soviet Union and the Culture of the Cold War
Authors: Carr Graham
Published: February 2014

Abstract:

The article examines the history of Glenn Gould's 1957 concert tour of the ussr as a pivotal moment in the Cold War and the evolution of Canadian cultural diplomacy. Classical music was a disarming weapon in the conduct of foreign relations because it was understood to have universal significance that transcended politics and ideology, even though the critical rhetoric of music performance often invoked notions of artistic power and triumph. Gould was the first North American pianist to perform behind the Iron Curtain, and his visit was a spectacular success artistically and politically. Western commentators played up his individualism, national identity, and modernist repertoire, describing the impact of his performances on Soviet audiences and translating the significance of that experience back home. Privately endorsed, but not officially sponsored by the Canadian government, the tour was organized by Gould's manager, Walter Homburger. Drawing on government documents about the planning of the tour, media coverage, personal memoirs, and the lectures about culture in the ussr that Gould delivered on his return to Toronto, the article explores the role of non-state actors in advancing the interests of Canadian foreign policy both at home and abroad.
Representing Wildlife Management: Sustainable Hunting Narratives at the International Wildlife Museum
Authors: Paulson Nels
Published: February 2014

Hunting is an important basis for conservation, but hunters are surprisingly scarce in global networks of environmental advocacy and governance, and hunting management systems are not given the attention they should receive. This article reveals the messages promoted by hunting advocates through an analysis of museum representations and interviews in order to understand the limitations of and basis upon which further integration of hunters into conservation advocacy circles worldwide could occur. Museums feature representations that reflect the cultural elucidations of their host organization. This article will show how the International Wildlife Museum—maintained by Safari Club International—produces messages of the inseparability of humans from nature, purposive management of nature, dependence upon global capitalism and predation, and the neutrality of scientific knowledge. Through these messages a narrative space for the management of wildlife is produced that attempts to unite the commodification and conservation of nature, namely, “sustainable hunting”. This article concludes by identifying contradictions among the messages of sustainable hunting that may limit hunting advocates' ability to work with other stakeholders to further improve hunting management systems.
Endoscopic third ventriculostomy and choroid plexus cauterization in posthemorrhagic hydrocephalus of prematurity
Authors: Chamiraju Parthasarathi , Bhatia Sanjiv , Sandberg David I. , Ragheb John
Published: February 2014

Object

The aim of this study was to determine the role of endoscopic third ventriculostomy and choroid plexus cauterization (ETV/CPC) in the management of posthemorrhagic hydrocephalus of prematurity (PHHP) and to analyze which factors affect patient outcomes.

Methods

This study retrospectively reviewed medical records of 27 premature infants with intraventricular hemorrhage (IVH) and hydrocephalus treated with ETV and CPC from 2008 to 2011. All patients were evaluated using MRI before the procedure to verify the anatomical feasibility of ETV/CPC. Endoscopic treatment included third ventriculostomy, septostomy, and bilateral CPC. After ETV/CPC, all patients underwent follow-up for a period of 6–40 months (mean 16.2 months). The procedure was considered a failure if the patient subsequently required a shunt. The following factors were analyzed to determine a relationship to patient outcomes: gestational age at birth, corrected age and weight at surgery, timing of surgery after birth, grade of IVH, the status of the prepontine cistern and cerebral aqueduct on MRI, need for a ventricular access device prior to the endoscopic procedure, and scarring of the prepontine cistern noted at surgery.

Results

Seventeen (63%) of 27 patients required a shunt after ETV/CPC, and 10 patients did not require further CSF diversion. Several factors studied were associated with a higher rate of ETV/CPC failure: Grade IV hemorrhage, weight 3 kg or less and age younger than 3 months at the time of surgery, need for reservoir placement, and presence of a normal cerebral aqueduct. Two factors were found to be statistically significant: the patient's corrected gestational age of less than 0 weeks at surgery and a narrow prepontine cistern on MRI. The majority (83%) of ETV/CPC failures occurred in the first 3 months after the procedure. None of the patients had a complication directly related to the procedure.

Conclusions

Endoscopic third ventriculostomy/CPC is a safe initial procedure for hydrocephalus in premature infants with IVH and hydrocephalus, obviating the need for a shunt in selected patients. Even though the success rate is low (37%), the lower rate of complications in comparison with shunt treatment may justify this procedure in the initial management of hydrocephalus. As several of the studied factors have shown influence on the outcome, patient selection based on these observations might increase the success rate.
Tissue-engineered intervertebral discs: MRI results and histology in the rodent spine
Authors: Grunert Peter , Gebhard Harry H. , Bowles Robby D. , James Andrew R. , Potter Hollis G. , Macielak Michael , Hudson Katherine D. , Alimi Marjan , Ballon Douglas J. , Aronowitz Eric , Tsiouris Apostolos John , Bonassar Lawrence J. , Härtl Roger
Published: February 2014

Object

Tissue-engineered intervertebral discs (TE-IVDs) represent a new experimental approach for the treatment of degenerative disc disease. Compared with mechanical implants, TE-IVDs may better mimic the properties of native discs. The authors conducted a study to evaluate the outcome of TE-IVDs implanted into the rat-tail spine using radiological parameters and histology.

Methods

Tissue-engineered intervertebral discs consist of a distinct nucleus pulposus (NP) and anulus fibrosus (AF) that are engineered in vitro from sheep IVD chondrocytes. In 10 athymic rats a discectomy in the caudal spine was performed. The discs were replaced with TE-IVDs. Animals were kept alive for 8 months and were killed for histological evaluation. At 1, 5, and 8 months, MR images were obtained; T1-weighted sequences were used for disc height measurements, and T2-weighted sequences were used for morphological analysis. Quantitative T2 relaxation time analysis was used to assess the water content and T1ρ-relaxation time to assess the proteoglycan content of TE-IVDs.

Results

Disc height of the transplanted segments remained constant between 68% and 74% of healthy discs. Examination of TE-IVDs on MR images revealed morphology similar to that of native discs. T2-relaxation time did not differ between implanted and healthy discs, indicating similar water content of the NP tissue. The size of the NP decreased in TE-IVDs. Proteoglycan content in the NP was lower than it was in control discs. Ossification of the implanted segment was not observed. Histological examination revealed an AF consisting of an organized parallel-aligned fiber structure. The NP matrix appeared amorphous and contained cells that resembled chondrocytes.

Conclusions

The TE-IVDs remained viable over 8 months in vivo and maintained a structure similar to that of native discs. Tissue-engineered intervertebral discs should be explored further as an option for the potential treatment of degenerative disc disease.
Surgical outcomes using a medial-to-lateral endonasal endoscopic approach to pituitary adenomas invading the cavernous sinus
Authors: Woodworth Graeme F. , Patel Kunal S. , Shin Benjamin , Burkhardt Jan-Karl , Tsiouris Apostolos John , McCoul Edward D. , Anand Vijay K. , Schwartz Theodore H.
Published: February 2014

Object

This study details the extent of resection and complications associated with endonasal endoscopic surgery for pituitary tumors invading the cavernous sinus (CS) using a moderately aggressive approach to maximize extent of resection through the medial CS wall while minimizing the risk of cranial neuropathy and blood loss. Tumor in the medial CS was aggressively pursued while tumor in the lateral CS was debulked in preparation for radiosurgery.

Methods

A prospective surgical database of consecutive endonasal pituitary surgeries with verified CS invasion on intraoperative visual inspection was reviewed. The extent of resection as a whole and within the CS was assessed by an independent neuroradiologist using pre- and postoperative Knosp-Steiner (KS) categorization and volumetrics of the respective MR images. The extent of resection and clinical outcomes were compared for medial (KS 1–2) and lateral (KS 3–4) lesions.

Results

Thirty-six consecutive patients with pituitary adenomas involving the CS who had surgery via an endonasal endoscopic approach were identified. The extent of resection was 84.6% for KS 1–2 and 66.6% for KS 3–4 (p = 0.04). The rate of gross-total resection was 53.8% for KS 1–2 and 8.7% for KS 3–4 (p = 0.0006). Six patients (16.7%) had preoperative cranial neuropathies, and all 6 had subjective improvement after surgery. Surgical complications included 2 transient postoperative cranial neuropathies (5.6%), 1 postoperative CSF leak (2.8%), 1 reoperation for mucocele (2.8%), and 1 infection (2.8%).

Conclusions

The endoscopic endonasal “medial-to-lateral” approach permits safe debulking of tumors in the medial and lateral CS. Although rates of gross-total resection are moderate, particularly in the lateral CS, the risk of permanent cranial neuropathy is extremely low and there is a high chance of improvement of preexisting deficits. This approach can also facilitate targeting for postoperative radiosurgery.
Brain involvement by leprosy presenting as a frontal cystic lesion
Authors: Lee Kyung-Hwa , Moon Kyung-Sub , Yun Sook Jung , Won Young Ho , Lee Jae-Hyuk , Lee Min-Cheol , Jung Shin
Published: February 2014

Leprosy has a predilection for peripheral nerves and is not considered to involve the CNS. The idea that the CNS is exempt from Mycobacterium leprae bacilli has been suspected from a clinical perspective or CSF study in leprosy patients. However, there has been no direct evidence for CNS involvement by leprosy in a living patient. To the best of the authors' knowledge, the present case is the first report providing histopathological and molecular evidence for CNS involvement by leprosy in a living patient. Brain MRI revealed a 2-cm cystic lesion in the right frontal lobe of the patient. The medical history revealed that the patient had been receiving multidrug therapy for borderline lepromatous leprosy. Neuronavigation-guided craniotomy and lesion removal were performed due to a presumptive diagnosis of low-grade glioma. The brain specimen demonstrated variably thickened blood vessels and densely scattered foamy macrophages in the perivascular spaces and parenchymal stroma. Fite acid-fast stain displayed red granular inclusions that were suggestive for fragmented M. leprae. M. leprae-specific nested polymerase chain reaction amplification showed positive bands, and DNA sequencing also demonstrated homology with the M. leprae genome. This case supports the notion that M. leprae can involve the cerebral cortex regardless of cranial nerve engagement.
Medial acoustic neuromas: clinical and surgical implications
Authors: Dunn Ian F. , Bi Wenya Linda , Erkmen Kadir , Kadri Paulo A. S. , Hasan David , Tang Chi-Tun , Pravdenkova Svetlana , Al-Mefty Ossama
Published: February 2014

Object

Medial acoustic neuroma is a rare entity that confers a distinct clinical syndrome. It is scarcely discussed in the literature and is associated with adverse features. This study evaluates the clinical and imaging features, pertinent surgical challenges, and treatment outcome in a large series of this variant. The authors postulate that the particular pathological anatomy with its arachnoidal rearrangement has a profound implication on the surgical technique and outcome.

Methods

The authors conducted a retrospective analysis of 52 cases involving 33 women and 19 men who underwent resection of medial acoustic neuromas performed by the senior author (O.A.) over a 20-year period (1993–2013). Clinical, radiological, and operative records were reviewed, with a specific focus on the neurological outcomes and facial nerve function and hearing preservation. Intraoperative findings were analyzed with respect to the effect of arachnoidal arrangement on the surgeon's ability to resect the lesion and the impact on postoperative function.

Results

The average tumor size was 34.5 mm (maximum diameter), with over 90% of tumors being 25 mm or larger and 71% being cystic. Cerebellar, trigeminal nerve, and facial nerve dysfunction were common preoperative findings. Hydrocephalus was present in 11 patients. Distinguishing intraoperative findings included marked tumor adherence to the brainstem and frequent hypervascularity, which prompted intracapsular dissection resulting in enhancement on postoperative MRI in 18 cases, with only 3 demonstrating growth on follow-up. There was no mortality or major postoperative neurological deficit. Cerebrospinal fluid leak was encountered in 7 patients, with 4 requiring surgical repair. Among 45 patients who had intact preoperative facial function, only 1 had permanent facial nerve paralysis on extended follow-up. Of the patients with preoperative Grade I–II facial function, 87% continued to have Grade I–II function on follow-up. Of 10 patients who had Class A hearing preoperatively, 5 continued to have Class A or B hearing after surgery.

Conclusions

Medial acoustic neuromas represent a rare subgroup whose site of origin and growth patterns produce a distinct clinical presentation and present specific operative challenges. They reach giant size and are frequently cystic and hypervascular. Their origin and growth pattern lead to arachnoidal rearrangement with marked adherence against the brainstem, which is critical in the surgical management. Excellent surgical outcome is achievable with a high rate of facial nerve function and attainable hearing preservation. These results suggest that similar or better results may be achieved in less complex tumors.
Smoking and postoperative outcomes in elective cranial surgery
Authors: Alan Nima , Seicean Andreea , Seicean Sinziana , Schiltz Nicholas K. , Neuhauser Duncan , Weil Robert J.
Published: February 2014

Object

The goal in this study was to assess whether a current or prior history of smoking and the number of smoking pack years affect the risk for adverse outcomes in the 30-day postoperative period in patients who undergo elective cranial surgery.

Methods

Data from the 2006–2011 American College of Surgeons' National Surgical Quality Improvement Project were used in this study. The authors identified 8296 patients who underwent elective cranial surgery, of whom 1718 were current smokers, 854 were prior smokers, and 5724 were never smokers. Using propensity scores and age, the authors matched current and prior smokers to never smokers. Odds ratios for adverse postoperative outcomes were predicted with logistic regression. The relationship between number of pack years and poor outcomes was also examined.

Results

In unadjusted analyses, prior and current smokers did not differ from never smokers for having poor outcomes postoperatively. Similarly, in matched analyses, no association was found between smoking and adverse outcomes. Number of pack years in propensity-matched analyses did not predict worse outcomes in prior or current smokers versus never smokers.

Conclusions

The authors did not find smoking to be associated with 30-day postoperative morbidity or mortality. Although smoking cessation is beneficial for overall health, it may not improve the short-term (≤ 30 days) outcome of elective cranial surgery. Thus postponement of elective cranial cases only for smoking cessation may not be necessary.
Novel embalming solution for neurosurgical simulation in cadavers
Authors: Benet Arnau , Rincon-Torroella Jordina , Lawton Michael T. , González Sánchez J. J.
Published: February 2014

Object

Surgical simulation using postmortem human heads is one of the most valid strategies for neurosurgical research and training. The authors customized an embalming formula that provides an optimal retraction profile and lifelike physical properties while preventing microorganism growth and brain decay for neurosurgical simulations in cadavers. They studied the properties of the customized formula and compared its use with the standard postmortem processing techniques: cryopreservation and formaldehyde-based embalming.

Methods

Eighteen specimens were prepared for neurosurgical simulation: 6 formaldehyde embalmed, 6 cryopreserved, and 6 custom embalmed. The customized formula is a mixture of ethanol 62.4%, glycerol 17%, phenol 10.2%, formaldehyde 2.3%, and water 8.1%. After a standard pterional craniotomy, retraction profiles and brain stiffness were studied using an intracranial pressure transducer and monitor. Preservation time—that is, time that tissue remained in optimal condition—between specimen groups was also compared through periodical reports during a 48-hour simulation.

Results

The mean (± standard deviation) retraction pressures were highest in the formaldehyde group and lowest in the cryopreserved group. The customized formula provided a mean retraction pressure almost 3 times lower than formaldehyde (36 ± 3 vs 103 ± 14 mm Hg, p < 0.01) and very similar to cryopreservation (24 ± 6 mm Hg, p < 0.01). For research purposes, preservation time in the cryopreserved group was limited to 4 hours and was unlimited for the customized and formaldehyde groups for the duration of the experiment.

Conclusions

The customized embalming solution described herein is optimal for allowing retraction and surgical maneuverability while preventing decay. The authors were able to significantly lower the formaldehyde content as compared with that in standard formulas. The custom embalming solution has the benefits from both cryopreservation (for example, biological brain tissue properties) and formaldehyde embalming (for example, preservation time and microorganism growth prevention) and minimizes their drawbacks, that is, rapid decay in the former and stiffness in the latter. The presented embalming formula provides an important advance for neurosurgical simulations in research and teaching.
Pial synangiosis in patients with moyamoya younger than 2 years of age
Authors: Jackson Eric M. , Lin Ning , Manjila Sunil , Scott R. Michael , Smith Edward R.
Published: February 2014

Object

Patients with moyamoya who are younger than 2 years of age represent a therapeutic challenge because of their frequent neurological instability and concomitant anesthetic risks. The authors report their experience with pial synangiosis revascularization in this population.

Methods

The authors reviewed the clinical and radiographic records of all patients with moyamoya in a consecutive series of patients under 2 years of age, who underwent cerebral revascularization surgery using pial synangiosis at a single institution.

Results

During a 12-year period (1994–2005), 34 procedures (bilateral in 15 patients, unilateral in 4) were performed in 19 patients younger than 2 years (out of a total of 456 procedures in 240 patients). Eighteen of these patients presented with either stroke or transient ischemic attack. The average age of the 19 patients at first surgery was 1.4 years (range 6 months–1.9 years). Unanticipated staged operations occurred in 3 patients, due to persistent electroencephalographic changes during the initial surgery in 2 cases and due to brain swelling during the procedure requiring ventriculostomy in the other. There were 2 perioperative strokes; both patients had postoperative seizures but made clinical recoveries. The average follow-up was 7 years (range 1–14 years). Long term, at follow-up, 13 patients (68%) were clinically independent for their age, with 8 (42%) having no significant deficit. Late complications included subdural hygroma evacuation (1), additional revascularization procedures performed years later for frontal lobe ischemia (2), late infarction (1), and asymptomatic ischemic change on routine follow-up MRI studies (1). All patients who had both pre- and postoperative angiography demonstrated progression of disease.

Conclusions

Despite the challenges inherent to this population, the majority of children with moyamoya under the age of 2 years have a good long-term prognosis. The data from this study support the use of pial synangiosis as a safe, effective, and durable method for treatment of moyamoya for most children in this potentially high-risk population.