bluuebunny/crossref_metadata_2025 huggingface dataset:
Work-Life Balance and Affective Commitment: The Moderating Role of Collectivism
Authors: Zaid Ahmed
Published: November 2023

The purpose of the current study is to examine the impact of work-life balance (WLB) for Small and Medium Enterprises (SME) employers and their employees’ affective commitment (AC), as well as the role of collectivism as a moderator between these constructs. A questionnaire was applied to collect data from 276 practitioners working in SMEs in Palestine. Partial least squares structural equation modelling (PLS-SEM) was used to analyze the data. The numerical results showed a substantial influence of WLB on AC and that collectivism also played a role as a moderator in the relationship between these constructs. Additionally, the study found that collectivism moderated the WLB – AC relationship. The implications of this research suggest that enhancing AC levels can promote workplace balance. This study contributes to an understudied association between WLB and AC in Palestinian SMEs, where the concept of collectivism is rarely utilized in relation to WLB and AC.
Unleashing the Economic Potential of Balochistan: The Dynamic Power of District Hub
Authors: Khan Khalid , Liaqat Saima
Published: November 2023

Balochistan, one of Pakistan's largest and resource-rich provinces, faces significant challenges in realizing its economic potential. Despite abundant natural resources, Balochistan suffers from some of the country's worst poverty rates, with the second-highest multidimensional poverty rate after the formerly Federally Administered Tribal Areas. The sparse population across a vast land area poses a significant growth constraint due to low population density, challenging terrain, and high per-unit service delivery costs. The lack of urban clusters exacerbates the problem of regional disparity, with Quetta being the only large city in the province. Nevertheless, Hub district stands out as Balochistan's most productive district, with the agricultural, fisheries, and livestock industries contributing significantly to its economy. Moreover, the district is Balochistan's only industrial and financial center, producing, on average, 90% of the province's industrial output and generating 70% of its tax revenue. As one of the thriving districts of Balochistan, District Hub needs reorganization along with new lines that unleash its economic potential and become the economic growth engine of Balochistan. However, to fully realize Balochistan's potential, further measures must be taken to address the challenges of low population density, logistical difficulties, and regional disparity.
Uji Daya Antiinflamasi Ekstrak Etanolik Daun Mengkudu (Morinda Citrifolia (L.)) Terhadap Mencit Putih (Mus Musculus) Jantan Galur Swiss Yang Diinduksi Karagenin
Authors: Paulina Maya Octasari  , Andreas Napoleon
Published: November 2023

Inflammation is the body's response to protect it self from chemicals, infectious agents, and damage to body tissues caused by injury. Flavonoid compounds can be used as anti-inflammatory by inhibiting the activity of cyclooxygenase (COX) and lipoxygenase enzymes. The amount of flavonoid content in noni leaves was 15.97 mg QE/g extract. The difference between this study and the previous research conducted by Rifaldy, et al (2019) lies in the test animals, the method of measuring inflammation, and the dose of extract used. This study aims to determine the anti-inflammatory power and dosage of the ethanolic extract of noni (Morinda citrifolia (L.)) leaves. This study is an experimental study, using a completely randomized design with one-way pattern with one treatment factor, namely variations in the dose of Noni Leaf Ethanolic Extract (EEDM), namely 42 mg/20gBW mice, 56 mg/20gBW mice, and 70 mg/20gBW mice. The anti- inflammatory test method uses artificial edema formation with carrageenin. The research data was in the form of percentage of anti-inflammatory power (%DAI), thenstatistically analyzed using SPSS with 95% confidence level. The results of the anti-inflammatory power of EEDM from the smallest to the largest doses produced anti-inflammatory properties, namely 55.30%, 62.28%, and 69.41%, this means that the larger the dose, the higher the percentage of anti-inflammatory power (p<0.05). The percentage of anti-inflammatory power of EEDM at a dose of 70 mg/20gBW mice had an anti-inflammatory effect that was not significantly different from the positive control (p>0.05).
PERBANDINGAN AKTIVITAS ANTIOKSIDAN SARI DAUN BAYAM MERAH (Amaranthus tricolor L.) SEGAR DAN REBUS DENGAN METODE DPPH (1,1–diphenyl-2-picylhydrazyl)
Authors: Sekar Maulida Qurotul Aini  , Nita Fajaryanti  , F.X Esti Mediastini
Published: November 2023

One of the highly nutritious vegetables because it contains a lot of protein, vitamin A, vitamin C and mineral salts that are needed by the body and contains anthocyanins which are useful in curing anemia. The purpose of this study was to determine the antioxidant activity and to determine the comparison between fresh and boiled red spinach leaf extract using the DPPH method. The research method used is an experimental method with a post test only control group design research by comparing the differences in the antioxidant activity content of fresh and boiled red spinach leaves. This study used red spinach which was divided into 2 groups, namely the fresh group and the boiled group. Each group of spinach was replicated 5 times using various concentrations (2500 ppm, 5000 ppm, 10000 ppm 15000 ppm, and 20000 ppm) for each replication. A linear regression analysis was performed between the concentration of fresh and boiled red spinach juice. The results showed that there was a very significant difference in antioxidant activity between fresh and boiled red spinach leaves. Fresh and boiled red spinach leaves have weak antioxidant activity due to IC50 150 g/ml. Fresh red spinach leaves have greater antioxidant activity, namely the IC50 value of 237,251 g/ml, while boiled red spinach leaves have an IC50 value of – 279,412 µg/ml.

Keywords: Red spinach (Amaranthus tricolor L.), Antioxidant, DPPH.
Pengobatan Oral Dan Topikal Squamous Cell Carsinoma
Authors: Wizar Putri Mellaratna  , Cut Tasya Miranda
Published: November 2023

Squamous Cell Carsinoma, (SCC) adalah tumor ganas kulit nonmelanoma yang berasal dari keratinosit suprabasal epidermis. Kanker kulit dapat diklasifikasikan dalam tiga tipe terbanyak yaitu karsinoma sel basal, karsinoma sel skuamosa, dan melanoma maligna.  Insiden kanker kulit di Amerika tercatat 4,9 juta kasus pada tahun 2007 – 2011 dengan rasio kanker non melanoma (kanker sel basal dan kanker sel skuamosa) dengan melanoma maligna adalah 6:1. Tatalaksana SCC bisa berupa terapi bedah dan non bedah, dimana terapi bedah seperti eksisi bedah, lebih disukai operasi yang dikontrol secara mikroskopis (bedah Mohs), Pengobatan metastasis nodal mungkin melibatkan diseksi kelenjar getah bening, radiasi, atau kombinasi keduanya. Terapi non bedah dapat berupa terapi topikal sistemik, radiasi, diseksi KGB, dll.
Faktor-Faktor Yang Mempengaruhi Kesehatan Reproduksi Pada Remaja SMP Di Wilayah Kerja Puskesmas Tanjung Unggat Kota Tanjungpinang Kepulauan Riau
Authors: Redayanti Redayanti  , Sri Muharni  , Rachmawaty M.Noer
Published: November 2023

The biggest problem faced by teenagers in Indonesia is adolescent reproductive health problems, including unwanted pregnancy (UTD), abortion, early marriage and marriage, STDs or STDs and HIV/AIDS (Marmi et al, 2020). The aim of this research is to determine the factors that influence reproductive health in junior high school adolescents in the Tanjung Unggat Community Health Center working area. This type of research is quantitative descriptive with a cross sectional approach. The sampling method in this research is total sampling or saturated sampling. The sample in this study consisted of 83 junior high school teenagers. Data collection methods and tools use questionnaires. The conclusion from the data analysis is that there is a relationship between knowledge and family support and reproductive health in junior high school adolescents in the Tanjung Unggat Community Health Center Working Area, Tanjungpinang City with a significant p value = 0.000 <0.05. Suggestions for health workers to provide education about adolescent reproductive health, so that adolescents avoid problems related to adolescent reproductive health.
RETROSPECTIVE EVALUATION OF BURDEN OF LUNG CANCER IN DIFFERENT ETHNIC GROUPS AND GENDERS AT KARACHI, PAKISTAN
Authors: Khaliq Sheikh Abdul , S. Naqvi Syed Baqir , Fatima Anab , Siddiqui Maria
Published: November 2023

Lung cancer is a third leading cancer in Pakistan with high mortality rate. To determine incidences in the population of Karachi, Pakistan, a retrospective study in different ethnic group was conducted from January 2011 to December 2015 to determine incidences of lung cancer in last five years registered in oncology wards of major hospitals of Karachi. Registered patients of lung cancer with confirmed diagnosis cytologically and/or histologically was included in the study. Secondary data from retrospective patient’s charts and files have been gathered. Most of the cases were from city of Karachi, Interior Sindh and Balochistan provinces. Minimum sample size of study was 147, however, evaluation was done on 169 patients. In addition to type of cancer, ethnicity, gender and age were also recorded. SPSS 20 software was employed for analysis including mean age, standard deviation, standard error and co-efficient of variation. Number of cases and incidences of lung cancer in different ethnic groups were found to be; Sindhi male 51 (38%), Sindhi female 12 (34%), Urdu speaking male 32(24%), Urdu speaking female 09 (26%), Balochi male 10 (07%), Balochi female 04 (11%), Pukhtoon male 09 (07%), Pukhtoon female 03 (09%), Punjabi male 25 (19%), Punjabi female 05 (14%), Siraikis male 03 (02%) minorities and other males 04 (03%), minorities and other females 02 (06%). Highest incidences are observed in Sindhi and Urdu speaking population of Sindh province, especially in male. Active, passive smoking, air-pollution and occupational exposure could be reason of high number of incidences in major ethnic groups of Karachi, therefore screening parameters are of paramount importance to reduce the burden of disease.
APPLICATION OF INNOVATIVE NANOMATERIALS TO RESOLVE IMMINENT ANTIMICROBIAL RESISTANCE
Authors: Ahmad Khan Tanveer
Published: November 2023

The foremost worldwide community issue of health is due to virulent bacteria and successively increasing antimicrobial-resistant against these microorganisms. The renowned disease control center stated that the world entered a post-antibiotic horizon, where the death rate from the microorganism will be more from cancer disease. In the ongoing period, new techniques such as nanoparticles emerge and are used against the virulent strains of microorganisms. Those difficulties faced by common antimicrobials such as antibiotic-resistant can be overcome by the advancement of nanotechnology. The nanomaterial (selenium, cobalt, silver, cobalt, cadmium, zinc oxide, and magnetic) plays a vital role in the delivery vehicle and surface therapeutic agents for a cargo of antimicrobial drugs. In this review, we presented the use of nanoparticles as an efficient system for antibacterial applications.
A REVIEW ON COMPARISON OF DIFFERENT TECHNIQUES USED TO ENHANCE DISSOLUTION OF VALSARTAN AND TELMISARTAN ORAL SOLID DOSAGE FORM
Authors: Abdul Khaliq Sheikh , Iqbal Samia , Siddiqui Shumaila , Javed Shakeeb , Anwer Sohail
Published: November 2023

Telmisartan and Valsartan are strong angiotensin-II type 1 receptor inhibitor, applied in the care of elevated blood pressure. Telmisartan and also Valsartan comes under Class II category of BCS classification. Valsartan and Telmisartan both are highly pH dependent and poor soluble drug which result in improper absorption and low bioavailability (43% and 23% respectively). In order to control the poor solubility as well as bioavailability of both Telmisartan and Valsartan, different formulation techniques are compared on the basis of dissolution. In this review article, solid dispersion by kneading method, pelletization by pan coating, modified microcrystalline cellulose (MCC) pellets and solid self-micro-emulsifying drug delivery system (SMEDDS) formulation techniques are discussed for Telmisartan. Whereas, in case of Valsartan, liquisolid compact technique, fast disintegrating tablets (FDT), and formulation optimized by 23 factorial designs are evaluated. To sum up, the analogy of Telmisartan formulations demonstrates that solid dispersion (TS5) and fast dissolving pellet formulation (TP3), both the techniques showed better drug release profile than MCC pellet and SMEDDS techniques. However, when it comes to dissolution rate, fast dissolving pellet formulation reflects notably best results among all. Furthermore, Valsartan formulation techniques evaluation leads us to conclude that liquisolid method showed good release profile as compare to conventional products but the method incorporates some complex requirements of load factor calculation and saturation solubility studies. In addition to that, Valsartan formulation optimized by factorial design as well as fast dissolving tablet (FDT) formulation signifies more conventional approach as well as good drug release profile.
IN SILICO PHARMACOKINETIC PROFILING OF TRYPTAMINE DERIVATIVES BY SWISSADME AND ADMETSAR
Authors: Asghar Saira , Iqtadar Rabia
Published: November 2023

Profiling of different pharmacokinetic parameters like the absorption, distribution, metabolism, and elimination known as ADME properties of drug molecules during initial phase of drug development might be beneficial in selection of molecules with less adverse ADME characteristics. ADME screening by in vivo testing is very time consuming, costly, and includes the animals. On the other hand, in silico ADME investigation is cheaper, better and offers correct results rapidly. In the current research study, the in-silico methods, namely SwissADME and admetSAR were used for brief and complete ADME profiling of previously selected (SR7, SR9, SR11, SR29, SR41 and SR43) tryptamine derivatives. The webservers utilized in this research are available for free. In-silico analyses have revealed that all the derivatives under study have high gastrointestinal absorption which make them a good oral drug candidate. However, results showed that SR41 & SR43 were able to pass blood- brain barrier as compared to other synthetic compounds of this series.
FUNCTIONAL FOODS OF PAKISTAN AND THEIR ROLE IN SENESCENCE
Authors: Maaz Hira , Abbas Ghulam
Published: November 2023

Functional foods can be used as a tool for healthy & longer life span. The term “functional food” is tossed to emphasize the role of nutritive substances in the prevention and eradication of chronic disease development. The aim of this study is to identify functional foods of Pakistan for their anti-aging potential. In this regard, the ethanolic extract or fresh juices of fifty functional foods, mostly advised by nutritionists, were assessed for their ability to inhibit glycation and oxidative stress. Our analysis showed that out of 50 functional foods, 44 of them have significantly reduced the formation of advanced glycation end products. The Pomegranate peel extract, Strawberry juice, coffee powder, and areca nut showed more than 90% AGEs inhibition at the concentration of 1 mg/ml. Furthermore, antioxidant potential of all these 50 functional foods was also assessed for antioxidant activity using DPPH assay. In this assay, the most pronounced effect (90% free radical scavenging activity) was observed with Cumin seeds extract, Purple Onion extract, Grapefruit juice and Oregano extract. In conclusion, the present study highlights several easily available dietary substances of Pakistan, whom consumption can help prevent age related disabilities and may contribute to healthier and longer life span.
ANADOLU’DA HAÇ PLANLI TÜRBE HAMZA-İ KEBİR
Authors: Boylu Hazal Bihter
Published: November 2023

Akkoyunlular, 14. yüzyıl sonu ile 15. yüzyıl arası Anadolu’da maddi kültür içerisinde bir hayli eser bırakmış ve Güneydoğu Anadolu ve Doğu Anadolu bölgelerinde egemenlik kurmuş bir devlettir. Mezopotamya olarak da bilinen bölge geçmişten beri birçok kültüre, dile, inanca ve medeniyete ev sahipliği yapmıştır. Çalışmamıza konu olan Akkoyunlular tarafından yapılan Hamza-i Kebir Camiihaçvari bir plana sahiptir. Anadolu da yer alan Türk mimarisinde haçvari plan şeması Selçuklu Dönemi türbelerinin kriptalarında sıkça karşılaşılan bir uygulama olmakla birlikte, ziyaret mekanlarında nadiren kullanılmıştır. Bu çalışmada, Hamza-i Kebir Cami’nin mimari analizi yapılarak türbenin plan şeması bakımından Anadolu Türbe Mimarisi içindeki önemi vurgulanacak; türbe üzerinde yapılan çalışmaların değerlendirilmesi yapılacaktır.
Paseamos entre la desinformación
Authors: Ollé Candela
Published: November 2023

Cómo se fabrican, cómo se difunden y cómo se pueden identificar las noticias falsas son tres grandes cuestiones que encuentran su respuesta, en parte, en la exposición Fake News. La fábrica de mentiras. El recorrido de la exposición empieza en la antigua Roma y acaba con las inteligencias artificiales (generativas) y deep fakes actuales. El punto de inflexión se produce con la irrupción de internet y de las redes sociales, puesto que desde entonces la explosión desinformativa ha ido in crescendo.
Evolution of the Resort Architecture in Jūrmala
Authors:   , Vērpe Baiba
Published: November 2023

The study analyses the genesis and transformation of Jūrmala’s built environment and architecture from the early 19th century to the present day. It focuses on the city as the largest resort in Latvia. The work analyses the terminology of the resort and the documentation of the spatial development planning of Jūrmala and identifies the built-up areas that have been used as resorts in one of the periods. The typological diversity and development of resort facilities, as well as their functional and technical transformation over time, are identified. The distribution of particular styles or stylistic trends in the built environment is examined. The main regularities of the development of Jūrmala resort architecture are formulated. The study introduces new factual and graphological material into the scientific literature.
ROLE OF ECONOMIC AND POLITICAL FREEDOM IN COUNTRY'S ATTRACTIVENESS OF FOREIGN DIRECT INVESTMENT (FDI): EVIDENCE FROM THE SOUTH EAST EUROPE
Authors: Mahmutović Hasan , Alibašić Elvis
Published: November 2023

The aim of this research is to empirically explore impact of economic and political freedom as two nontraditional factors on FDI inflows in eight of South East Europe countries between 2002 and 2020. Accordingly, the study hypothesis that high level of economic and political freedom is positively associated with FDI. The study uses panel data techniques. The obtained findings of the study failed to confirm contribution of economic freedom on FDI in eight South East European countries. It can be explained that a given level of reforms conducted in the field of business freedom, trade freedom, monetary freedom, investment freedom, government size, property rights, freedom from corruption, labour freedom, financial freedom, and fiscal freedom are still lagging from developed countries. On the contrary, the findings confirmed the impact of political freedom on FDI attractiveness and that given level of political freedom contributes to growth of FDI.
THE IMPACT OF SENSITIVITY ANALYSIS ON THE EVALUATION OF THE LOGISTICS PERFORMANCE INDEX
Authors: Erceg Živko , Kovačević Biljana
Published: November 2023

The logistics performance index (LPI) represents an important indicator of the state of logistics and its development in countries. The LPI is directly linked to the level of economic system development, and as such provides an adequate basis for the improvement of economy, through logistics and trade. The aim of this paper is to determine the impact of sensitivity analysis on the evaluation and ranking of the LPI in the Balkan countries, according to the report of the World Bank. Sensitivity analysis implies the change of the importance of six criteria based on which the LPI ranking is done. The multi-criteria decision-making model (MCDM), which consists of CRITIC and MARCOS methods for determining the LPI rank in the Balkan countries, was previously used. Criteria weights are simulated through 36 scenarios, whereby the weights of the observed criteria change in the range of 15% - 90%. The final results show that criteria values play very important role in the ranking of the Balkan countries, when it comes to the LPI.
DIGITAL TRANSFORMATION AS AN ECONOMIC CHALLENGE IN THE CONDITIONS OF ACCELERATED GLOBAL CHANGES
Authors: Soldić-Aleksić Jasna , Јakovljević Aleksandra
Published: November 2023

The mass application of digital technologies has brought substantial changes to the business environment and everyday life of people. The digital transformation is provoking an intense debate among policy makers, economists and industry leaders about its social impact and economic challenges. Conflicting views on the effects and consequences of digitalisation and digital transformation often arise, ranging from the completely optimistic views about future trends to the views that indicate reasons for concern about their possible negative impact. The aim of this paper is to point out the most significant economic challenges of digital transformation in the conditions of accelerated global changes. The paper emphasizes that digital transformation creates disruptive „chaos“ in some areas, while at the same time in other areas it leads to business improvement. Also, the paper considers the position of Serbia from the aspect of economic challenges brought by digitalization and digital transformation. Accelerated global change due to the development of technology requires that all economies, if they want to be successful, must adapt to "digital time". In this adjustment, it is especially important to avoid possible negative impacts of digitalization and application of digital technologies in all spheres of life and in the business environment. This especially refers to the possibility of creating or increasing the digital divide in all its manifestations, and some of them are especially emphasized in this paper.
COMPARATIVE ANALYSIS OF THE TRADE PERFORMANCE OF THE COUNTRIES OF THE EUROPEAN UNION, SERBIA AND BOSNIA AND HERZEGOVINA - EMPIRICAL APPROACH
Authors: Lukić Radojko
Published: November 2023

The issue of measuring and analyzing trade performance is continuously relevant, significant and complex. It is particularly challenging to investigate trading performance using different multi-criteria decision-making methods. In this way, considering the comparison of a large number of alternatives in relation to several criteria, a more realistic knowledge of trade performance is gained in the function of improvement in the future by applying relevant measures. Based on that, this paper analyzes the trade performance of the countries of the European Union, Serbia and Bosnia and Herzegovina based on the LMAW-DNMA method. According to the results of the LMAW-DNMA method, the top five countries of the European Union in terms of trade performance include: France, Germany, Spain, Poland and Italy. In terms of trade performance, the leading countries of the European Union (Germany, France and Italy) are well positioned. Malta is positioned in the last place. In terms of trade performance, Croatia is better positioned than Slovenia (21st and 23rd place, respectively). Serbia ranked twenty-second in terms of trade performance. It is positioned worse than Croatia, but it is better than Slovenia. The trade of Bosnia and Herzegovina took twenty-sixth place in terms of performance. It is worse positioned in relation to the performances of Croatia, Slovenia and Serbia. In order to improve the trade performance of European Union countries, especially Serbia and Bosnia and Herzegovina, it is necessary to manage more efficiently the number and size of companies, human resources, employee costs, turnover and added value. The target profit can be achieved by adequate control of these and other critical factors of business success.
IMPACT OF GLOBAL MOVEMENTS ON ECONOMIC GROWTH AND FISCAL STABILITY IN THE REPUBLIC OF SRPSKA
Authors: Srdić Gojković Bilјana , Krsmanović Branko , Krajišnik Milenko
Published: November 2023

The world economy has been exposed to intense cyclical movements since the beginning of the 21st century. After the global economic crisis of 2008, several years of stabilization and recovery followed. Тhe last few years have seen global disruptions caused by various factors, such as: the migrant crisis, the crisis caused by the COVID-19 pandemic and the current crisis in Ukraine. This resulted in a disruption in the energy market, global inflation, disrupted supply chains and the growth of protectionism in international trade, with a strong impact on economic developments in the Republic of Srpska. Republika Srpska, as a small and open economy at a lower level of development, is highly exposed to movements on the global market, and especially to oscillations of economic activity in countries with which it has intensive economic relations. Exports in Republika Srpska are highly correlated with its economic growth and efficient use of available resources. But Republika Srpska is import dependent in many sectors. Monetary policy is based on the principle of the monetary board, and the economic development of Republika Srpska is directly conditioned by foreign direct investments. These facts are conditioned by the economic trends in the Republic of Srpska. The question is to what extent global disturbances affect economic developments in the Republic of Srpska and how these developments affect its fiscal stability? This paper provides a quantification of the impact of the economic trends of the most important foreign trade partners of Republika Srpska and the countries of the European Union on its economic growth. This analysis quantifies the impact of the economic development of Republika Srpska on fiscal stability. Based on the results of this analysis, the information is obtained as to show how dependent the economy of Republika Srpska is on external influences, and how fiscal stability is conditioned by its economic development.
УТИЦАЈ ДИГИТАЛНЕ ТЕХНОЛОГИЈЕ НА УПОТРЕБУ МОБИЛНЕ АПЛИКАЦИЈЕ У УГОСТИТЕЉСКИМ ОБЈЕКТИМА
Authors: Мићић Љубиша
Published: November 2023

Већ скоро двије године свијет се суочава са великим економским изазовима, a један од њих је како прилагодити пословање једног привредног субјекта условима пандемије. Са великом сигурношћу се може рећи да постоји врло мало привредних субјеката на које пандемија није оставила трага, нанијела видљиве посљедице на пословање. Међутим, може ли се криза перципирати као шанса за даљи развој, могућност да се остваре бољи резултати у односу на конкуренцију? Један од начина побољшавања рада угоститељских објеката јесте и имплементација дигиталних технологија употребом мобилне апликације. Сходно томе, основни циљ рада јесте да утврдимо да ли дигиталне технологије утичу на употребу мобилне апликације у угоститељским објектима. Методе кориштене за истраживање биће упитник као метод квантитативног истраживања, те интервју, као метод квалитативног истраживања. Очекивани резултати истраживања јесу утврђивање постојања утицаја дигиталних технологија на употребу мобилне апликације у угоститељским објектима.
DINAMIKA PROMENA OSNOVNIH ELEMENATA PREDUZEĆA
Authors: Kontić Ljiljana , Todosijević Miloš
Published: November 2023

Novi pogled na elemente koji čine preduzeće i njegovo okruženje donela nam je kibernetika. Svaka promena koja se dogodi u bilo kom prirodnom ili organizacionom sistemu ima rušilački karakter. Intenzitet snage zavisi od otpora koji se emituje prema sadržaju promene. Sa nastupajućom promenom, manifestuje se i dvojno dejstvo tehničkog progresa ¬– afirmativno (progresivno) i obezvređujuće (regresivno). Promene pod dejstvom tehničkog progresa dovode do poremećaja u funkcionisanju organizacionih sistema. Narušava se ravnoteža kako između elemenata koji konstituišu sistem, tako i između preduzeća i njegove okoline. Kibernetika identifikuje snagu i dinamiku promena i nastoji da stvari i procese dovede u prvobitno ravnotežno stanje. Nužno je za kibernetiku uvažavati pojave sredine u kojoj egzistira organizacioni sistem i njihov uticaj na dešavanja u upravljanim sistemima. Preduzeće nije izolovani sistem već na zakonit način uspostavlja raznovrsne veze između pojedinih delova unutar sebe i sa okolinom. U radu ćemo naglasak staviti na elemente koji, nameravano ili autonomno, najčešće izazivaju i dovode do promena. Simbolički ćemo predstaviti okruženje u kome se odvija ceo proces razvoja preduzeća, kao i parcijalne komplekse tog procesa koji čine: razvoj proizvoda, razvoj tržišta, razvoj resursa, te razvoj kapaciteta i procesa rada. Ako je rešenje nastalih problema izazvanih promenama poželjno ili poznato, algoritam je uvek moguće postaviti.
Diritto casistico alla corte imperiale di Costantinopoli. Presentazione dell’opera a cura di Dieter Simon e Diether Roderich Reinsch (Milano, 14 aprile 2023)
Authors: Ferrari Monica
Published: November 2023

Abstract On 14 April 2023 the presentation of the book Ἡ Πεῖρα - Die Peira: Ein juristisches Lehrbuch des 11. Jahrhunderts aus Konstantinopel was held at the University of Milan. The work consists of an edition, translation and commentary of a collection of jurisprudential cases from the Byzantine era. The publication of the two volumes, edited by Dieter Simon and Diether Roderich Reinsch, created an opportunity for discussion and dialogue on various topics pertaining to Byzantine law, for which the Peira is an important source of knowledge.
Per i cinquant’anni della Costantiniana. Tra bilanci e prospettive: Oriente e Occidente in dialogo
Authors: Lanti Lorenzo
Published: November 2023

Abstract This paper provides the «Cronaca» of the XXVIth International Conference of the Accademia Romanistica Costantiniana, held in Spello from 15 to 17 June 2023. The event marked an important milestone: the 50th anniversary of the Research Centre of the University of Perugia. In consideration of this special anniversary, the inaugural session was intended to recompose the historiographical lines drawn by the «Accademia» in this fifty-year period and to outline new research perspectives. In the subsequent sessions, the more than twenty-five papers that followed dealt with relations between East and West in a multiform perspective: in particular, the mobility of people, the circulation of legal knowledge and the comparison of divergent legislative choices between the partes Imperii were explored.
Demokratiserande læringsprosessar
Authors: Bruland Inger Oline
Published: November 2023

Studiar om studentar sine erfaringar med uformell brukarmedverknad i høgare utdanning er etterspurt. Det er ynskjeleg at studentane deltek i demokratiserande lærings- og vurderingsprosessar, sidan dei har førstehandserfaring med kva som er viktig for dei. Hensikta med studien var å utforske og beskrive korleis sjukepleiarstudentar i tredje studieåret erfarer eigen medverknad i teoriemnet psykisk helsearbeid. Data vart samla inn ved fokusgruppeintervju med seksten studentar og analysert gjennom kvalitativ innhaldsanalyse. Funna vart drøfta i høve til korleis sjukepleiarstudentar erfarer eigen brukarmedverknad innafor autonomien dei har i sjukepleiarutdanninga sine teoretiske læringsinitiativ. Studentane erfarer at visse rammefaktorar, som til dømes store klassar, utfordrar prosessane. Studentane medverkar gjennom sine læringsstrategiar og ulike læringsformer. Brukarmedverknaden er størst når studentane arbeider i små grupper der dei får øvd seg praktisk på grunnlag av skrivne kasus med rettleiing frå lærar.
Helsepersonells prevensjonsveiledning
Authors: Rosten Caroline Norheim , Dammen Siri , Aune Ingvild
Published: November 2023

En stor andel unge kvinner i Norge bruker prevensjon og har oppsøkt helsepersonell for å få prevensjonsveiledning og resept på prevensjonsmidler. På tross av dette er det utført lite forskning i Norge som undersøker kvinners erfaringer med prevensjonsveiledning, og hva som påvirker deres valg av prevensjonsmiddel. Hensikten med studien var å få kunnskap om hvilke erfaringer unge kvinner har med å motta prevensjonsveiledning hos helsepersonell, og hvilke faktorer som påvirker deres valg av prevensjonsmiddel. Studien har et kvalitativt design, og det ble utført ti individuelle intervjuer. Datamaterialet ble analysert ved bruk av systematisk tekstkondensering. Dette resulterte i tre resultatkategorier; «Opplevelse av tilfredshet med prevensjonsveiledning», «Personlige preferanser påvirker valget» og «Sosial påvirkning og helsepersonells anbefalinger». Studien avdekket et forbedringspotensial ved prevensjonsveiledningen de unge kvinnene mottok hos helsepersonell. Ulike faktorer som påvirket kvinnenes valg ble belyst, noe som er relevant kunnskap for helsepersonell å inneha ved prevensjonsveiledning av unge kvinner.
Higher physical activity level and perceived social support is associated with less psychological distress in people with anxiety
Authors: Pereira-Payo Damián , Denche-Zamorano Ángel , Mayordomo-Pinilla Noelia , Franco-García Juan Manuel , Castillo-Paredes Antonio , Garcia-Gordillo Miguel Angel , Rojo-Ramos Jorge , Barrios-Fernández Sabina
Published: November 2023

Introduction

Anxiety is one of the most prevalent mental illnesses in first world societies, generating discomfort in the people who suffer from it, and high expenses and economic losses in the society. The physical activity (PA) performed, together with the perceived social support (PSS) by people with anxiety could be related to the psychological distress of people with anxiety.

Objectives

To study the relationships between mental health and its dimensions, through Golberg’s General Health Questionnaire (GHQ12), and the level of PA (PAL) and the PSS in the Spanish adult population with anxiety.

Hypothesis

A higher PAL, and a higher PSS, is related to a lower psychological distress in this population.

Design and Methodology

This study included 1,661 adults with anxiety, residents in Spain. It was a cross-sectional study with data obtained from the Spanish National Health Survey. A Kolmogorov–Smirnov test was applied to examine the data distribution of the variables. The median and interquartile range were used to characterize the sample for continuous variables, and absolute and relative frequencies were used for categorical variables. The Mann–Whitney U test was used to examine the differences between sexes. Dependence between PAL and sex was studied using the chi-square statistic. A Krustal–Wallis test was used to evaluate the existence of differences in the baseline medians on the GHQ-12, according to PAL level. Finally, the correlations between mental health and its dimensions with PAL and the Duke-UNC-11 scores were analysed, obtaining Spearman’s rho and Pearson’s correlation coefficient.

Results

Moderate inverse correlations were found between the GHQ-12 and: PAL (rho: −0.219); PSS (r: −0.347). PAL and PSS presented moderate inverse correlations with successful coping (rho: −0.206 and r: −0.325), self-esteem (rho: −0.222 and r: −0.333) and stress (rho: −0.158 and r: −0.288).

Conclusions

Greater PAL and social support are associated with reduced psychological distress in people with anxiety.
Modulación y control distribuido basados en consenso para convertidores modulares multinivel en cascada con almacenamiento de energía
Authors:   , Donoso Ballart Álvaro Francisco
Published: November 2023

El creciente uso de fuentes de energía renovables ha puesto en evidencia la importancia de los sistemas de almacenamiento de energía en baterías (BESS) para mitigar los desequilibrios de potencia que surgen debido a su naturaleza variable e intermitente. Los convertidores modulares multinivel en cascada (MMCC) se presentan como uno de los candidatos mas atractivos para aplicaciones BESS, principalmente debido a su estructura modular inherente. Sin embargo, esta modularidad se ve limitada por los esquemas de control altamente centralizados utilizados en la actualidad. Por ello, estudios recientes presentan esquemas de control descentralizados y distribuidos, que buscan superar las desventajas de los controles centralizados, pero ninguno logra aprovechar al máximo la modularidad de los MMCCs. Para solucionar este problema, en esta tesis se propone un esquema de control totalmente distribuido cooperativo, en el cual un conjunto de controladores locales (LC), idénticos e independientes, adosados a cada uno de los submódulos (SM), logran los objetivos de control mediante consenso. El esquema propuesto se compone de una estrategia de control predictivo de modelo (MPC), un control de estado de carga (SoC) de las baterías y un algoritmo de sincronización de los LCs. La novedad de esta propuesta permite desconectar y conectar cualquier SM sin detener el funcionamiento del convertidor, y la integración de un ajuste automático en la modulación de las señales de control, lo cual proporciona escalabilidad y un rendimiento invariable a la salida del convertidor, independiente del número de SMs activos. La propuesta se valida de forma experimental en un cluster de un conversor CHB conectado a la red, con lo cual se evidencia la capacidad de aprovechar por completo la modularidad de los MMCCs.
Enfoque de programación dinámica aproximada para la calendarización de tratamientos de quimioterapia en una red de atención oncológica
Authors:   , Wenzel Fernández Arturo Eduardo
Published: November 2023

En este paper enfrentamos un problema de calendarización de sesiones de quimioterapia en un sistema de salud que opera en red. En este sentido, consideramos que los pacientes llegan a alguno de los centros de tratamiento de la red con la indicación de su oncólogo tratante para que se realice alguno de los diferentes protocolos de tratamiento existentes. Cada protocolo de tratamiento presenta diferente número y duración de sesiones, tiempo entre sesiones y tiempos de espera máximos para la primera sesión. Que el sistema estudiado opere en red exige que los pacientes deben realizarse su primera y su última sesión de su protocolo de tratamiento en el centro de tratamiento al que fueron enviados por su oncólogo, y que pueden realizarse las sesiones intermedias en un centro de tratamiento diferente al que fueron enviados por su oncólogo. Para resolver el problema, lo modelamos como un proceso de decisión markoviano, el cual resolvemos de manera aproximada utilizando técnicas de programación dinámica aproximada. Los beneficios del enfoque propuesto son evaluados y comparados con el enfoque manual existente, simulando su funcionamiento para un caso práctico que considera diferentes protocolos y los centros de tratamiento de la Red de salud UC CHRISTUS y del Hospital del Salvador. Lo anterior nos permite evaluar los beneficios de considerar un enfoque proactivo (enfoque propuesto) en vez de uno reactivo (enfoque manual existente) y el impacto de considerar un sistema que opera en red. Nuestro enfoque permite disminuir los costos de operación de la red en un 20% y reduce los tiempos de espera promedio de los pacientes por su primera sesión aproximadamente a la mitad en comparación con el enfoque utilizado actualmente. Una de las conclusiones más importantes de nuestro estudio es que un sistema de tratamiento que opera en red, como el propuesto, solo obtienen beneficios si se considera una política proactiva en la calendarización de tratamientos.
Terrazas marinas cuaternarias y variabilidad en las tasas de alzamiento en la zona costera andina (23°S)
Authors:   , Vergara Torrejón Paulina Judith
Published: November 2023

Durante el Cuaternario gran parte de la región costera occidental de los Andes se ha estado alzando, principalmente por procesos de subducción. En el norte de Chile, la geomorfología de la Península de Mejillones y sus alrededores se caracteriza por la existencia de Terrazas Marinas Cuaternarias (TMQ), acantilados, diques, escarpes, etc. Estos elementos geomorfológicos se preservan debido a la hiperaridez del área desde el Plio-Pleistoceno. Las TMQ han sido estudiadas para entender la deformación permanente del antearco y calcular tasas de alzamiento a lo largo de la costa. Un análisis morfométrico utilizando sensores remotos ALOS-PALSAR, levantamiento topográfico con drone y GPS diferencial, muestreo de fósiles, además del uso de software, han permitido definir las secuencias de terrazas marinas (TM) mejor preservadas y calcular tasas de alzamiento. A partir de este análisis se propone una nueva distribución de las TM y se calculan tasas de alzamiento para estudiar el rol de las fallas en el alzamiento diferencial y la relación de estas estructuras con la distancia a la fosa. Para el análisis se ha considerado 2 áreas representativas: Morro Mejillones, al noroeste de la Peninsula de Mejillones (~12x10 km2) y la zona de Hornitos – Punta Chacaya (~16x7 km2), al norte de la Bahía de Mejillones. Se evidencian diferencias en características morfoestructurales y en tasas de alzamiento: se han identificado 12 TMQ en Morro Mejillones con tasas de alzamiento entre 0.31 a 0.76 m/ka para los últimos 600 ka; 3 TMQ en Hornitos con tasas de alzamiento entre 0.28 a 0.4 m/ka para los últimos 220 ka; y 4 TMQ en Punta Chacaya con tasas de alzamiento entre 0.25 y 0.39 m/ka para los últimos 350 ka. Las diferencias en tasas de alzamiento podrían estar relacionadas a la distancia de la fosa y la actividad de fallas durante el Cuaternario.
Modeling bloodflow and gas exchange in alveoli
Authors:   , Zurita Soler Pablo
Published: November 2023

El intercambio gaseoso es una función esencial del sistema respiratorio que se acopla fundamentalmente con la perfusión en los alvéolos. Formulaciones matemáticas actuales y modelos computacionales de estos dos fenómenos dependen de aproximaciones unidimensionales que obvian la microestructura volumétrica compleja de los arreglos alveolares. En este trabajo introducimos un modelo computacional tridimensional acoplado de perfusión pulmonar en los capilares e intercambio gaseoso que se adecúa a la morfología alveolar. Para este fin, derivamos ecuaciones diferenciales parciales no lineales y condiciones de borde desde principios físicos que gobiernan el comportamiento de la sangre y los gases en geometrías alveolares arbitrarias. Resolvemos la formulación resultante mediante una propuesta e implementación de un esquema de elementos finitos no lineales. Realizamos varios experimentos numéricos para validar nuestro modelo contra simulaciones de una dimensión y demostrar su aplicabilidad a geometrías inspiradas en morfología. Simulaciones numéricas muestran que nuestro modelo predice caídas de presión sanguínea y velocidades sanguíneas esperadas en los capilares pulmonares. Este comportamiento también se observa en geometrías alveolares tridimensionales, entregando más detalle asociado a la distribución espacial de campos de interés y la influencia de la forma del dominio. Creemos que este modelo abre la puerta a mejores estudios in silico de intercambio gaseoso y perfusión en geometrías realistas, modelos acoplados de intercambio gaseoso y mecánica respiratoria, y análisis multiescala de funcionamiento pulmonar; avanzando nuestro entendimiento de fisiología y patología pulmonar.
On the problem of the densest packing of spherical segments into a sphere
Authors: Vu Duc Thinh , Phung The Bao , Lempert A.A. , Nguyen Duc Minh
Published: November 2023

The paper considers a particular variant of the classical optimal packing problem when the container is a sphere, the packed elements are equal spherical caps, and the optimality criterion is to maximize their geodesic radius. At the same time, we deal with a special integral metric to determine the distance between points, which becomes Euclidean in the simplest case. We propose a heuristic numerical algorithm based on the construction of spherical Voronoi diagrams, which makes it possible to obtain a locally optimal solution to the problem under consideration. Numerical calculations show the operability and effectiveness of the proposed method and allow us to draw some conclusions about the properties of packings.
Effects of Stakeholder’s Management in Public Private Partnership on Implementation of Affordable Housing Projects in Meru County, Kenya
Authors: Muthoni Zipporah , Obuba Robert
Published: November 2023

More than half of the world's population of over six billion people reside in urban areas, placing increasing responsibility on governments to provide fundamental human necessities, including housing. This challenge is particularly pronounced in Kenya, where many County Government PPP affordable housing initiatives have either failed or been stalled. Both National and County Governments have experienced difficulties in executing these projects, reflecting the nascent stage of PPP application in many underprivileged countries. In Meru County, the Affordable Housing Project (AHP) employs PPP, primarily in the form of joint ventures. This approach distinguishes it from other existing projects and generates a knowledge gap regarding the assessment of the impact of public-private partnerships on the implementation of affordable housing initiatives in this region. The aim of this research was to explore the effects of stakeholder’s management in public private partnership on implementation of affordable housing projects in Meru County, Kenya. Guided by stakeholder theory, the study employed a descriptive research design, collecting data through a structured questionnaire. A proportionate stratified random sampling method was used to select the study sample from County officials, non-governmental organization managers, development partners' managers, and household heads from selected study areas where the projects have been initiated, notably in the Buri, Maweni, Mjini, and Makandara wards. A total of 395 questionnaires were issued to the sampled respondents from a total target of 31978 who included the stakeholders in affordable housing project estates in Meru County that included county official managers in DoLPH (15), NGO’s managers (25), development partners’ managers (5) engaged in affordable housing and household heads (350). The collected data was analyzed and results presented in tables and figures, the qualitative information was presented in prose.
Length‐weight Relationships of Four Indigenous Freshwater Fishes of Longshen Stream, Indo-Myanmar Borderline of North-East of India
Authors: Tenali Diamond Rajakumar , Madina Praveena , Rokkala Shashi Bala , Jamir Temjen Bursanen , Masram Vedika , Dann Lekiningroy , Yadav Nitesh Kumar
Published: November 2023

Length-weight relationships (LWR) are reported for four indigenous fish species of longshen stream, Indo-Myanmar boundary line North-Eastern Ghats of Indian region, for the period of June 2020 to September 2022. Specimen species were collected during different exploratory surveys, using through traditional bamboo made fishing gears. The b value for LWRs varied from 2.09(Barilius vagra) to 2.63(Garra lissorhynchus). R2 values varied from 0.85 to 0.95, indicating unique values. The results providing baseline information for the need of sustainable ecological as well as economical management and conservation of indigenous fish species in Indo-Myanmar borderlines