bluuebunny/crossref_metadata_2025 huggingface dataset:
Analysis of 3Vs of Big Data from Fake News and Nigerians’ Consciousness towards National Unity in Times of Uncertainties
Authors: Lasisi Mutiu Iyanda , Ajetunmobi Umar Olansile , Mustapha Muhammed Jamiu
Published: December 2021

Fake news seems to be the monster of the century affecting continents of the world. From Africa to Asia, America to the Himalayas, the impact of fake news on national unity and regional cohesion remains debatable among scholars and experts. Like other countries on the African continent, Nigeria has tasted and is still having share of the consequences of fake news, especially politically-driven ones, which has been researched by scholars in the media and emerging technologies spaces. This study joins the conversation within the journalism and fake news discourse using big data that emerged from selected political, security, health and religious fake news reported by selected Nigerian newspapers. Adopting Computational and Quantitative Content Analyses with the specific use of Data Logging Approach for data collection, the study investigates the extent to which the Nigerian public consume and spread the select news at the expense of promoting national unity and regional cohesion expected of citizens, as established in the Nigerian constitution and existing rules guiding public communication in the country. The emerging results point towards the need for the establishment of Media Literacy Commission to complement the efforts of ministries saddled with the responsibility of re-orientating journalists, media establishments and citizens on national consciousness and unity. The outcomes of the study also indicate the need for overhauling of the National Orientation Agency (NOA) towards balanced and connected promotion of national values and norms.
Assessing patient experience and attitude: BSC-PATIENT development, translation, and psychometric evaluation - a cross-sectional study
Authors: Amer Faten , Hammoud Sahar , Onchonga David , Alkaiyat Abdulsalam , Nour Abdulnaser , Boncz Imre , Endrei Dóra
Published: December 2021

Background
Improving the healthcare sector in Palestinian territories is challenging. Organizations frequently use the balanced scorecard (BSC) for performance evaluation (PE) worldwide. BSC includes an evaluation of five perspectives: financial, customer, internal process, knowledge and innovation, and environmental. Most HealthCare Organizations (HCO) evaluated patient satisfaction in BSC, but none considered engaging patients in the evaluation process. This paper aims to develop an instrument to engage patients in assessing BSC perspectives at Palestinian hospitals (BSC-PATIENT).
Methods
This is a cross-sectional descriptive study. Two panels of experts participated in the item generation of BSC-PATIENT. Forward and backward translation processes from English to Arabic and vice versa were performed. Pretesting was performed for 30 patients at one hospital. Then, 1000 patients were recruited at 14 hospitals between January and October 2021. Construct validity was tested through exploratory factor analysis (EFA) and confirmatory factor analysis (CFA). Additionally, the composite reliability (CR), interitem correlation (IIC), and corrected item total correlation (CITC) were assessed to find redundant and low correlated items.
Results
The scales had high adequate model fit in EFA and CFA. All items included had loadings higher than 0.50. Although the convergent validity was less than 0.50 for some constructs, their discriminant validity, CR, IIC, and CITC showed satisfactory results except the services experience (SERV EXR) construct, which had a CR of 0.50. The final best fit model in CFA comprised ten constructs with 34 items.
Conclusion
BSC-PATIENT is the first self-administered questionnaire specially developed to engage patients in evaluating their experiences and attitudes based on the BSC perspectives. The questionnaire scales were carried out following relevant guidelines and regulations. The results showed adequacy in the psychometric properties of this instrument. Three-point Likert scales are recommended to assess patient experiences and attitudes since they have higher response rates. Future research can be conducted using this instrument to evaluate the impact of patient experience on attitudes toward BSC perspectives and compare the differences based on patient and hospital characteristics.
Longitude and Latitude Based Received Signal Strength Difference Localization Models
Authors: Ma Fangli , Xu Yang , Xu Peng
Published: December 2021

In order to use the latitude and longitude coordinates for received signal strength difference (RSSD) localization, the errors of several spherical distance calculation methods and the error of arc length relative to string length were compared. The distance-calculation RSSD localization equations were established, including spherical accurate calculation RSSD, spherical approximate calculation RSSD, and normal cylindrical projection RSSD. And then, the optimization RSSD localization models based on geodetic coordinates and corresponding to the above equations were established, and the models were verified using the point by point search method with good convergence. The numerical results show there are a lot of weak localization areas for the RSSD localization networks lack of central stations with 4,5,6 stations. Among networks with central stations, there are only a small number of weak-localization areas for the concave 4 stations network, while there are no weak-localization areas for the networks composed of more stations. When the measurement errors and the additional losses of radio wave propagation are not considered, the localization errors of the spherical accurate model, the spherical approximate model and the equianglular projection model are very small, among which the second model has the shortest localization time. The localization errors of equidistance projection model and equal-area projection model are large, neither of which is suitable for the middle latitude and high latitude areas.
A Comparison of Initial Developments Between Explosive and Ordinary Mid-latitude Cyclones Off the East Asian Coast in Winter
Authors: Gao Xiaoyu , Lu Ping , Hu Yang , Zhang Shuqin , Sun Xiaoyan , Zhang Qiuyang
Published: December 2021

Explosive cyclones (ECs) off the East Asian coast post challenges in forecasting and significant threats to human life and property. In searching for the key features that distinguish explosive cyclones (ECs) from ordinary extratropical cyclones (OCs), this study presents detailed comparison of winter ECs versus OCs in the perspective of potential vorticity (PV) using 10 years of reanalysis data with high temporal and spatial resolutions. ECs feature greater low-level baroclinity and stronger PV than OCs. The decomposition of local PV tendency shows the important contribution of cold advection (with correlation coefficient of 0.8) in the initial development of ECs. A stronger cold advection for ECs increases upstream static stability, leading to intrusion of higher PV along the steeper isentropic surfaces. The importance of cold advection is further proved by numerical experiments with the Weather Research and Forecast (WRF) model on a typical winter EC. The weakening of cold advection within low-troposphere in sensitivity experiment can significantly decrease PV and stop the cyclone from explosive deepening. In addition to the consensus that diabatic processes play important roles in the intensification of explosive cyclogenesis, this study emphasizes the importance of horizontal cold advection (which is also associated with baroclinic instability) in the preconditioning PV for explosive cyclogenesis.
Spatiotemporal Variability of Weather Extremes Over Eastern India: Evidences of Ascertained Long Term Trend Persistence and Effective Global Climate Controls
Authors: Saha Saurav , Chakraborty Debasish , Hazarika Samarendra , Shakuntala I. , Das Bappa , Chhabra Aakash , Sadhu S , Chakraborty Debashis , Mukherjee J , Singson Lungmuana , Mishra V.K.
Published: December 2021

The present study acknowledged climate variability induced periodic variation in localized extreme weather event occurrences under diverse agro eco-regions of Eastern Himalayas of India during past five decades. The widespread rise in warm nights (TN90p; 0.31-1.67 days year-1), reduced daily rainfall intensity (SDII) and changes in other weather extremes viz. temperature and precipitation extremes signified clear signals on regional atmospheric warming across eastern India. The agro-ecological regions under extended Bramhaputra valley and coastal belts of south Bengal experienced the most persistent shifts in temperature extremes, while the upper Himalayan range extended from North Bengal to Arunachal Pradesh experienced the steepest decline in average daily rainfall intensity and other absolute quantitative estimates of precipitation extremes over past five decades. Together with El Niño and La Niña events, large scale global atmospheric circulations particularly expansion of warmer Pacific Warm Pool (PWP) and changes in Atlantic Meridional Mode (AMM) contributed the periodic dynamics in weather extreme occurrences from monthly to annual time scale over eastern India. Our findings will be useful for better understanding of regional climatology, designing and successful implantation of location-specific suitable agricultural policies towards climate change adaptation in near future.
A Mixed-Methods Study of the Technical Feasibility and Patient Acceptability of a Real-Time Adherence Monitor in Breast Cancer Survivors Taking Adjuvant Endocrine Therapy
Authors: Bright Emma E. , Genung Sarah R. , Stanton Annette L , Arch Joanna J.
Published: December 2021

Purpose: Oral anti-cancer medications are increasingly common and endocrine therapies represent the most common oral anti-cancer medications in breast cancer. Adjuvant endocrine therapies reduce the likelihood of recurrence and mortality in the approximately 80% of women diagnosed with hormone-receptor positive breast cancer, thus rendering adherence essential. Real-time medication adherence monitors, such as the Wisepill electronic pillbox, transmit adherence data remotely, allowing for early intervention for non-adherence. However, their feasibility and acceptability have yet to be examined among breast cancer survivors taking endocrine therapies.Methods: This study presents quantitative patient-report and technical support data and qualitative patient acceptability data on using Wisepill, a common real-time adherence monitor, among 88 breast cancer survivors prescribed adjuvant endocrine therapy.Results: This mixed-methods study of a common real-time adherence monitor, among the first in breast cancer survivors taking adjuvant endocrine therapy, demonstrates its technical feasibility and patient acceptability.Conclusion: The use of wireless medication monitors that transmit real-time adherence data are uniquely promising for maximizing the benefits of adjuvant endocrine therapy by allowing for continuous tracking, ongoing communication with oncologic or research teams, and early intervention. This study demonstrates the feasibility and patient acceptability of one such real-time adherence monitor.
Clinical and immunological efficiency of different therapy regimens in patients with infectious mononucleosis caused by Epstein-Barr virus
Authors: Ksenia Pavlikova , Liadova Tetiana , Volobueva Olga , Gololobova Olesya , Vinnikova Nataliia
Published: December 2021

The aim of the study was to evaluate the effectiveness of ribonucleic acid in the correction of immune disorders in patients with infectious mononucleosis (IM) caused by EBV.

Materials and methods. We examined 110 patients with a mean age of 23.3±4.2 years with IM, among whom women accounted for 52.7 % (n=58). The material for the study was the serum of patients obtained during the disease course. The set of tests of patients with IM included clinical and biochemical methods, enzyme-linked immunosorbent assay, polymerase chain reaction method, immunogram. Statistical processing of the obtained data was performed with “Statsoft Statistica v. 10.0 for Windows” using the methods of variation and correlation statistics.

Results. The obtained results analysis revealed changes in the system of cellular and humoral parts of the immune system and the diversity of the immune response in patients with IM. The progressive nature of changes in immune parameters indicated the formation of secondary cellular immune imbalance, activation of the humoral link, a change in the balance of immunoregulatory mediators towards Th2 cells. Significant changes in the cellular immune system were observed in the acute period and were characterized by the increase in the number of cells with killer activity, namely mature T-lymphocytes (CD3+), cytotoxic T-suppressor cells (CD8+), cells expressing the activation marker CD25+ (IL-2 receptor), and by the Th1/Th2 ratio increase. The appointment of combination therapy including ribonucleic acid was accompanied by immunomodulatory and antiviral effects, that was reflected in a more pronounced positive dynamics of immunological parameters, namely in strengthening the proliferative response, compared with the group of patients receiving only basic therapy.

Conclusion. The expediency of the combination therapy application: the drug Nuclex (ribonucleic acid) (250 mg) 2 capsules 3 times a day for 14 days and valacyclovir (500 mg) at a dose of 1000 mg (2 tablets) 3 times a day for 14 days, is justified for the correction of immune disorders in patients with IM caused by EBV.
Testing for Non-Linear Structures in Artificial and Real-World Financial Data with Recurrence Quantification Analysis
Authors: Giglio Ricardo , Silva Eduardo Ferreira
Published: December 2021

Early applications of empirical methods from chaos theory suggested the existence of low dimensional chaotic motion in empirical financial data. However, such results were questioned, and it is then believed that the search for low dimensional chaos in financial data was not successful. On the other hand, at the same time that the hypotheses that raw returns are independent and identically distributed (IID) is often rejected, they indeed present a quite small degree of autocorrelation. These facts suggest that prices in financial markets do not behave completely at random, although their hidden structures seem more complex than those observed in low dimensional chaotic systems. Previous work tested for non-linearity or the presence of low dimensional chaos in artificial financial data generated from the Lux-Marchesi model by means of the BDS and Kaplan tests. Addressing the same model, researchers extended those results by applying Hinich’s bi-spectral and White’s tests and introducing the application of Recurrence Quantification Analysis (RQA) on artificial financial data based on Recurrence Rate, Determinism, Entropy, and Maximal Diagonal Length. Contributing to this research, the present paper has two main goals: (i) to contrast previous findings with an RQA application on data generated by a more evolved of microscopic model of financial markets – the Structural Stochastic Volatility (SSV ) model; and (ii) to extend the RQA investigation above with additional recurrence measures (namely, Divergence, Laminarity, and Maximal Vertical Length) being applied to distinct real-world financial data. The objective is to assess if RQA results could help to distinguish between artificial and real-world data, even if linearity is rejected in both cases. It is shown evidence, in agreement previous findings, to support the rejection of linearity or low dimensional chaotic motion in an artificial financial time series generated from the SSV microscopic model. In addition, it is also shown that that RQA measures can help to discriminate artificial from real-world financial data, at least when specific RQA measures are considered.
NAFTOIMIDAZÓIS E NAFTOXAZÓIS - PROMISSORES COMPONENTES DE SISTEMAS TERANÓSTICOS
Authors: Santos Victória , Guimarães Délis , Nishimura Rodolfo , Rolim Larissa , Gonsalves Arlan , Araújo Cleônia
Published: December 2021

NAPHTHOIMIDAZOLES AND NAPHTHOXAZOLES - PROMISING COMPONENTS OF THERANOSTIC SYSTEMS. Theranostic can be used to define therapeutic and imaging agents in a system. It is consisting of four components: signal emitter, therapeutic agent, targeting ligand and carrier. Naphthoimidazole and naphthoxazole are extended aromatic systems, and can participate in theranostic systems (TS) acting as a therapeutic agent and/or a signal emitter considering of their broad spectrum of biological activities and their optical properties of fluorescence emission. This systematic review investigated the applicability of the naphthoimidazole and naphthoxazole nuclei as constituents of TS and shows the synthesis methodologies described in the articles selected. Among the scientific articles suitable for the criteria of the systematic review, more than 35% described the evaluation of biological activities, mainly the naphthoimidazole derivatives, and approximately 18% explored the fluorescence emission of naphthoxazole derivatives and their applicability in biological systems. Among the selected articles 53% and 44% show synthetic routes for the preparation of naphthoxazoles and naphthoimidazoles, respectively. It was observed that both nuclei can be synthesized from various reagents, such as naphthoquinones, naphthols, naphthoic acids, aminonaphthoquinones and cyanophthalides. The results of this study suggests that naphthoimidazole and naphthoxazole derivatives are promising for application as components of TS, and there are various synthetic possibilities for obtaining these heterocycles.
What's New in Molecular Targeted Therapies for Thyroid Cancer?
Authors: Min Seonyoung , Kang Hyunseok
Published: December 2021

Thyroid cancer refers to various cancers arising from thyroid gland. Differentiated thyroid cancers (DTCs) include papillary, follicular, and Hurthle cell carcinomas and represent cancers retain normal thyroid functions such as iodine uptake. Radioactive iodine (RAI) is generally used for upfront treatment of metastatic DTCs, but RAI refractory DTCs remain to be clinical challenges. Sorafenib and lenvatinib were approved for the treatment of RAI refractory DTCs and more recently, genomics-based targeted therapies have been developed for NTRK and RET gene fusion-positive DTCs. Poorly differentiated and anaplastic thyroid cancers (ATCs) are extremely challenging diseases with aggressive courses. BRAF/MEK inhibition has been proven to be highly effective in BRAF V600E mutation-positive ATCs and immune checkpoint inhibitors have shown promising activities. Medullary thyroid cancers, which arise from parafollicular cells of thyroid, represent a unique subset of thyroid cancer and mainly driven by RET mutation. In addition to vandetanib and cabozantinib, highly specific RET inhibitors such as selpercatinib and pralsetinib have demonstrated impressive activity and are in clinical use.
A Case of Buccal Pilomatricoma Removed Through Intraoral Incision
Authors: Kim Hong Dae , Park Min Kyu , Lee Hyeon A , Ji Yong Bae
Published: December 2021

Pilomatricoma(or calcifying epithelioma) is a not common benign solitary tumor originated from outer root sheath cell of hair follicle or hair follicle of sebaceous glands. The tumor usually presents as an asymptomatic, hard, superficial located, and skin colored to reddish blue cutaneous mass. Most of the tumors are less than 10mm in diameter and adherent to the skin. Recently, 48-year-old man presented with cheek mass. The tumor was 2.6cm sized and located at the subcutaneous layer of cheek on CT scan. The tumor was clearly removed via transoral approach with buccal incision leaving no wound on face. The mass was confirmed as pilomatricoma on pathologic examination. Herein, we report our experience with literature review.
The Concept of Complexity in Philosophical Contexts: Semantic and Pragmatic Specifics
Authors: Dumov Alexander
Published: December 2021

The present research featured the content of complexity in philosophical contexts in the aspects of its validity, consistency, and compliance with the pragmatics of philosophical comprehension of reality. The article considers both explicit and implicit attempts to define complexity as a philosophical concept. The author addressed the validity of using the term complexity in a philosophical context by standardizing its meaning, i.e. building a pattern in accordance with the basic linguistic denotations of this concept. A review of its ontological and epistemological use made it possible to identify some cases of redundancy, unreasonableness, and semantic shift. The article introduces some possible ways of using the concept of complexity. The limited implementation of its epistemic function makes it possible to establish the boundaries of its applicability. The concept of complexity is important for metaphysics; however, such ideas as "metaphysics of complexity", "ontology of complexity", or "epistemology of complexity" have no ground. The article also provides a comparative analysis of the concept of complexity in specific scientific and philosophical contexts. Based on the revealed discrepancies in its interpretation, the author speculates whether the so-called philosophy of complexity can act as a context for understanding the philosophical problems of complexity science with its ambiguous nature.
Forensic Medical Expertise in Traditional China: Legal Regulation and Practice
Authors: Dan'shin Aleksandr
Published: December 2021

The article deals with the problems of forensic medical expertise in traditional China in the investigation of crimes related to murder and death of people under unknown circumstances. The research featured legal acts and related comments that regulated the procedure. The author focused on the treatise of the XIII century Sung Tzu's "Washing Away of Wrongs" (Hsi yüan lu), which became the first essay on forensic medicine in world history. This document was far ahead of European works on this topic and was still in use in the early XX century. Constant conflicts between non-official comments and legal norms were one of the most serious problems that judicial practice had to face. For instance, according to the century-long shiht’u practice, specially authorized employees (wutso) with no medical training were responsible for describing internal and external injuries on the human body. Medical education was not mandatory for those performing forensic medical examination because autopsy was prohibited under the threat of punishment in the form of hard labor, and all conclusions about the causes of death were made on the basis of external examination. However, the main problem was the legal responsibility for the falsification of forensic medical examination. It often affected innocent people while real criminals managed to escape punishment, which violated the yin-yang harmony.
Strategizing of the Russian Far East Gas Industry: Systematization of Main Interests
Authors: Sasaev Nikita
Published: December 2021

ntroduction. The socio-economic development of the Russian Far East is one of the most important strategic directions of Russia, corresponding to the national interests and development vector. For this vector to be transmitted to the regional and sectoral level, it needs strategic opportunities, relevant in the context of multiple trends and limited resource base. Energy security includes reliable energy consumption and efficiency. It ensures the socio-economic progress of developing economies and emerging-market countries. The Russian Far East has accumulated enough scientific, technical, industrial, and production potential to use gas industry as a long-term driver of socio-economic development. The research objective was to analyze and systematize the main interest groups focused on the development of gas industry in the Russian Far East. Study objects and methods. The study was based on the theory of strategy and the methodology of strategizing developed by Professor V.L. Kvint, as well as on authentic methods of industrial strategizing. Results and discussion. The article introduces a concept scheme that illustrates the relationship between regional and sectoral gas strategies of the Russian Far East, as well as their place in the general system of strategies. The author systematized the main national, social, regional, industrial, corporate, and international interests. The analysis confirmed the long-term interest of the gas industry in the Far Eastern Federal District at each of these levels. Conclusion. In the Russian Far East, gas industry will establish strong vertical and horizontal relationships in the system of strategies, thus producing a multiplicative effect on the socio-economic development of the whole Far Eastern Federal District and its regions.
AS AÇÕES REGRESSIVAS PREVIDENCIÁRIAS DE TRÂNSITO: UMA QUESTÃO ECONÔMICO-SOCIAL, PREVIDENCIÁRIA E DE RESPONSABILIDADE CIVIL
Authors: UFRN PPGD
Published: December 2021

O presente artigo apresenta uma análise sobre os elementos que compõem as Ações Regressivas Previdenciárias de Trânsito, movidas pela Previdência Social, cuja titularidade compete ao Instituto Nacional do Seguro Social (INSS) e que representa, na atualidade, um dos assuntos mais polêmicos aos olhos do Direito Previdenciário brasileiro. Diante dos aspectos econômico-sociais, os elevados números de acidentes de trânsito envolvendo os segurados da Previdência Social acarretaram cerca de R$ 410 milhões com pagamento de benefício do tipo auxílio-doença, como também, R$ 4 bilhões com pagamento da aposentadoria por invalidez e R$ 3,2 bilhões com pagamento da pensão por morte. A conduta humana (negligência e imprudência) apresenta-se como a principal causadora desses acidentes e quando comprovada é alvo da Ação Regressiva Previdenciária de Trânsito, por parte da Procuradoria-Geral Federal do INSS. O INSS procura demonstrar a existência dos requisitos da responsabilidade civil (ação ou conduta humana – dano ou prejuízo – nexo causal) ao demandar suas ações regressivas contra o motorista infrator.
UMA ANÁLISE ACERCA DA EFETIVIDADE DO ATIVISMO JUDICIAL COMO GARANTIA DO ACESSO AO DIREITO À SAÚDE
Authors: UFRN PPGD
Published: December 2021

O presente artigo versa sobre a judicialização do acesso ao direito à saúde mediante o Ativismo Judicial. Tem por objetivo realizar uma definição de saúde, sua abrangência enquanto direito social fundamental, apontar a inefetividade das normas atinentes ao direito à saúde, bem como a busca constante - dos usuários do sistema único de saúde – ao Judiciário como forma de garantir o acesso ao direito à saúde. Para sua consumação, foi utilizado o método de abordagem dedutivo, os métodos de procedimento histórico, interpretativo e analítico, bem como as técnicas de pesquisa bibliográfica e documental. Cumprindo todos os objetivos estabelecidos, descreve que a saúde não é apenas a ausência de doenças, mas um conjunto de determinantes sociais que favorecem a dignidade da pessoa humana. Procede à análise da efetividade das normas constitucionais e infraconstitucionais que regulamentam o direito à saúde no Brasil. Critica a busca excessiva do Judiciário para garantir o acesso à saúde pública. Firma a conclusão de que o Ativismo Judicial é importante para o Estado Democrático, mas não é a melhor solução para a saúde pública brasileira.
A SUPERAÇÃO DA TENSÃO EXISTENTE ENTRE AS AGÊNCIAS REGULADORAS BRASILEIRAS E O REGIME DEMOCRÁTICO
Authors: Moura Kate de Oliveira , Neto Otacílio dos Santos Silveira
Published: December 2021

O presente trabalho tem por escopo estudar as agências reguladoras brasileiras sob a perspectiva do suposto déficit democrático atribuído a essas autarquias de regime especial. Inicialmente, serão destacadas as premissas no que tange a relação existente entre democracia e agências reguladoras no contexto do neoliberalismo. Em seguida, será feito uma análise a respeito da tensão existente entre as agências reguladoras brasileiras e o regime democrático. Assim, serão tecidos comentários a respeito da aferição de democracia dentro do modelo regulatório. O objetivo é demonstrar as diversas vias de legitimidade democrática observadas pela doutrina, quais sejam: i) a legitimidade democrática pelo título, isto é, com o sufrágio universal e; ii) a legitimidade pelo exercício do poder, pelo qual a atuação das agências se legitima pela perseguição incessante do interesse público. Na sequência, será vista a questão da participação popular no processo decisório das agências reguladoras como pressuposto indispensável para o alcance de uma regulação setorial democrática associado ao cumprimento das finalidades públicas destinadas a tais entes.
MODULAÇÃO DOS EFEITOS NO CONTROLE DE CONSTITUCIONALIDADE EM MATÉRIA TRIBUTÁRIA: UMA ANÁLISE SOB A ÓPTICA DA HERMENÊUTICA CONSTITUCIONAL
Authors: Costa Diógenes Malala Míriam Ludmila
Published: December 2021

O presente artigo propõe-se a discutir a modulação dos efeitos no controle de constitucionalidade no que atine a matéria tributária. O estudo objetiva verificar os métodos hermenêuticos salientes na interpretação constitucional, os quais permitirão constatar qual o método predominantemente aplicado no âmbito da jurisdição constitucional no que atine a aplicação da modulação dos efeitos da decisão. Busca ainda analisar decisão proferida pelo Supremo Tribunal Federal no âmbito tributário, correspondente a declaração de inconstitucionalidade da contribuição ao Fundo de Assistência Social ao Trabalhador Rural (FUNRURAL), a qual restou declarado a inconstitucionalidade da norma e não houve a modulação dos efeitos da decisão, constatando qual o método hermenêutico preponderante utilizado pelos julgadores.
CONSIDERAÇÕES SOBRE A ESCOLHA DO DIREITO MATERIAL APLICÁVEL AO MÉRITO DO LITÍGIO NA ARBITRAGEM INTERNACIONAL E O PAPEL DO ÁRBITRO
Authors: Mombach Matheus Martins Costa
Published: December 2021

A arbitragem como método alternativo na resolução de conflitos decorrentes de relações contratuais tem assumido importância crescente na comunidade internacional. Neste trabalho, enfrentaremos o problema da autonomia da vontade na arbitragem internacional, perquirindo ser ou não possível que as partes escolham livremente o direito material aplicável ao mérito de seus litígios para, em um segundo momento, investigarmos como o árbitro deverá agir ante a ausência de escolha expressa. A metodologia empregada consistirá majoritariamente no recolhimento e exame dos posicionamentos doutrinários, nacionais e internacionais, acerca do tema em questão, assim como na pontual apuração de decisões dos Tribunais Arbitrais e de diplomas internacionais. Ao que tudo indica, concluiremos ser possível, ao menos nas hipóteses de arbitragens internacionais, que as partes escolham o direito material a ser aplicado ao mérito de seus litígios. Na hipótese de ausência de escolha expressa, deverá o árbitro extrair dos critérios objetivos do contrato – do texto ou do contexto contratual – solução que aponte para escolha implícita, porquanto inexiste, em nenhum estatuto arbitral moderno, requerimentos a respeito da forma que a escolha deverá assumir, nada impedindo que se infira da conduta das partes a existência de acordo implícito. Sendo impossível averiguar tal escolha, quer por ausência de indícios objetivos suficientes, quer por discordância entre os contratantes a respeito do direito a ser aplicado, poderá o árbitro recorrer a diplomas internacionais que, por sua vez, não oferecem um método específico a ser seguido, concedendo uma razoável discricionariedade ao adjudicador externo.
CONCURSO APARENTE DE NORMAS E A CONSEQUENTE UNICIDADE DE REAÇÃO PUNITIVA DO ESTADO NO CRIME DE SONEGAÇÃO FISCAL MEDIANTE FRAUDE DOCUMENTAL
Authors: Pereira Patrícia Gondim Moreira
Published: December 2021

Este artigo aborda a questão do concurso aparente de normas. Para tanto, será apontado seu conceito, seu fundamento, critérios utilizados para resolução dessa aparente pluralidade de tipos incriminadores concorrentes, sempre sob a perspectiva da proibição do bis in idem, ou seja, sobre a impossibilidade de dupla apenação contra a mesma pessoa pelos mesmos fatos. Será apontado como os tribunais superiores têm resolvido o conflito aparente de normas em sede de crime de sonegação fiscal mediante fraude documental. Objetiva-se, assim, demonstrar que sem embargo da conduta praticada pelo agente subsumir-se hipoteticamente a mais de um tipo penal, há a ocorrência de um único delito, devendo ser aplicada uma única pena.
O PROCESSO JUDICIAL PREVIDENCIÁRIO, JUSTIÇA QUANTITATIVA E A SATISFATIVIDADE DA JURISDIÇÃO
Authors: Neto Melquiades Peixoto Soares
Published: December 2021

A jurisdição não deve mais atender somente o interesse subjetivo das partes, mas, na construção da decisão judicial, toda a sociedade tem interesse. Em matéria de Direitos Sociais Previdenciários a atividade do juiz deve sobrepor a materialização e construção do Direito em face da celeridade e eficiência processual, sob pena de não solucionar o conflito nem restabelecer a paz social. Neste aspecto, a tutela jurisdicional deve considerar a impossibilidade de retrocesso em matéria social, bem como os influxos neoliberais na construção de um conceito de celeridade, observando que o atingimento da decisão judicial perfaz todo o corpo social, de forma que se o indivíduo não for efetivamente protegido pelo Judiciário, de nada adiantará o atingimento de metas e o julgamento massivo de processos. Desta forma, o presente estudo, através de pesquisa bibliográfica e análise de dados estatísticos, considera o fator satisfatividade e celeridade em face da necessidade de um Direito á Previdência materializado e reconstruído
A ABSTRATIVIZAÇÃO DO CONTROLE DIFUSO DE CONSTITUCIONALIDADE NO ÂMBITO DO STF E A (IN)CONSTITUCIONALIDADE DOS ARTS. 525, §12º, 535, §5º, DO NOVO CÓDIGO DE PROCESSO CIVIL DE 2015
Authors: ARAUJO JÚNIOR AMARO BANDEIRA DE
Published: December 2021

RESUMO

 Os novos influxos relativos à abstrativização do controle difuso de constitucionalidade na jurisprudência do Supremo Tribunal Federal aliado aos dispositivos inseridos no novo Código de Processo Civil, em especial a norma insculpida no art. 525, §12º, revelam uma força normativa desproporcional legalmente fixada aos precedentes judiciais oriundos da Corte Constitucional brasileira que podem levar à violação das garantias constitucionais processuais. O presente trabalho intenta analisar a inconstitucionalidade do nóvel dispositivo processual, ao mesmo tempo em que busca realizar uma análise sobre o espectro possível de limitações hermenêuticas, para além daqueles tradicionalmente aplicados, que podem ser utilizadas para um controle racional mínimo dos fundamentos dos precedentes judiciais vinculantes oriundos das decisões tomadas em controle difuso de constitucionalidade pelo STF.

 Palavras-Chave: Abstrativização. Controle difuso. Constitucionalidade. Garantias processuais. Execução. Hermenêutica. Coisa julgada.

 

ABSTRACT 

The new influxes related to the abstractivization of the diffuse control of constitutionality in the jurisprudence of the Federal Supreme Court, combined with the provisions inserted in the new Code of Civil Procedure, especially the norm inscribed in art. 525, paragraph 12, reveal a disproportionate normative force legally fixed to judicial precedents from the Brazilian Constitutional Court that may lead to violation of constitutional procedural guarantees. The present work tries to analyze the unconstitutionality of the new procedural device, at the same time as it seeks to perform an analysis on the possible spectrum of hermeneutical limitations, beyond those traditionally applied, that can be used for a minimal rational control of the grounds of the binding legal precedents stemming from the decisions made in diffuse control of constitutionality by the STF.

 Keywords: Abstractivization. Diffuse control. Constitutionality. Procedural safeguards. Execution. Hermeneutics. Thing judged.
A DENSIDADE SEMÂNTICA DA KATCHANGA E A CRISE DA JURIDICIDADE NO BRASIL
Authors: Miranda Victor Pimenta
Published: December 2021

A moldura kelseniana propõe que a interpretação normativa deve ser sistêmica e o ordenamento jurídico deve ser coerente para que exista segurança nas relações sociais. O raciocínio interpretativo para aplicar corretamente uma norma deve encontrar respaldo no próprio ordenamento em que está inserido. Com efeito, a história da “Teoria da Katchanga” serve para metaforizar a dogmática jurídica atual da Suprema Corte brasileira, simbolizando como as decisões forenses e o entendimento dos ministros (“Katchanga Real”) mudam as regras do jogo e causam grande insegurança aos cidadãos.
Prevalence of White Spot Caries Lesions in Primary Teeth in Preschool Children: Systematic Review and Meta-analysis
Authors: Campos Priscila H. , Gimenez Thais , Rocha Rafael S. , Caneppele Taciana M.F. , Guaré Renata O. , Lussi Adrian , Bresciani Eduardo , Diniz Michele B.
Published: December 2021

Background:

The first clinically detectable stage of caries lesion is a non-cavitated
white spot lesion (WSL). The detection of early stages of caries lesions allows non-invasive management
by fluoride usage, oral hygiene and diet control. There is a lack of information in the literature
regarding the prevalence of these caries lesions in preschool children, which is important especially
for public health strategies.

Objective:

The aim of this study was to conduct a systematic review with meta-analysis to verify
the WSLs prevalence in primary teeth of preschool children.

Methods:

A literature search with MEDLINE/PubMed, Scopus, Web of Science, and Open Gray
databases was conducted. Included studies fulfilled the eligibility criteria. Meta-analyses were performed
using random effects model, for prevalence of pooled WSLs and subgroups analyses.

Results:

The search strategy identified 4922 potentially relevant articles, with final inclusion of 16
studies. The pooled prevalence of WSLs in primary teeth was 14.0% (95% CI: 8.0-24.0), without
publication bias (p=0.2668). For subgroup analyses, an increase in WSLs prevalence for children
of low-income economy (24.0%; 95% CI: 20.0-28.0), for age >31 months (22.0%; 95% CI:
12.0-37.0), for validated visual criteria assessment (20.0%; 95% CI: 11.0-33.0), and for tactile assessment
with ball-ended probe (26.0%; 95% CI: 11-50.0) were detected.

Conclusion:

It is suggested that the prevalence of WSLs in primary teeth of preschool children increases
in countries with low income economy, with age greater than 31 months or texture assessment
with visual validated criteria or ball-ended probe.

PROSPERO Registration:

Protocol number #CDR42017078434.
Distinguishing Intramedullary Spinal Cord Neoplasms from Non-Neoplastic
Conditions by Analyzing the Classic Signs on MRI in the Era of AI
Authors: Lim Ernest Junrui , Leong Natalie Wei Lyn , Ho Chi Long
Published: December 2021

:

Intramedullary lesions can be challenging to diagnose, given the wide range of possible
pathologies. Each lesion has unique clinical and imaging features, which are best evaluated using
magnetic resonance imaging. Radiological imaging is unique with rich, descriptive patterns and
classic signs-which are often metaphorical. In this review, we present a collection of classic MRI
signs, ranging from neoplastic to non-neoplastic lesions, within the spinal cord. The differential diagnosis
(DD) of intramedullary lesions can be narrowed down by careful analysis of the classic
signs and patterns of involvement in the spinal cord. Furthermore, the signs are illustrated memorably
with emphasis on the pathophysiology, mimics, and pitfalls. Artificial intelligence (AI) algorithms,
particularly deep learning, have made remarkable progress in image recognition tasks. The
classic signs and related illustrations can enhance a pattern recognition approach in diagnostic radiology.
Deep learning can potentially be designed to distinguish neoplastic from non-neoplastic processes
by pattern recognition of the classic MRI signs.
Non-histone Methylation of SET7/9 and its Biological Functions
Authors: Song Peng , Li Qing , Gao Lili , Yu Weiping
Published: December 2021

Background:

(su(var)-3-9,enhancer-of-zeste,trithorax) domain-containing protein 7/9
(SET7/9) is a member of the protein lysine methyltransferases (PLMTs or PKMTs) family. It contains
a SET domain. Recent studies demonstrate that SET7/9 methylates both lysine 4 of histone 3
(H3-K4) and lysine(s) of non-histone proteins, including transcription factors, tumor suppressors,
and membrane-associated receptors.

Objective:

This article mainly reviews the non-histone methylation effects of SET7/9 and its functions
in tumorigenesis and development.

Methods:

PubMed was screened for this information.

Results:

SET7/9 plays a key regulatory role in various biological processes such as cell proliferation,
transcription regulation, cell cycle, protein stability, cardiac morphogenesis, and development.
In addition, SET7/9 is involved in the pathogenesis of hair loss, breast cancer progression, human
carotid plaque atherosclerosis, chronic kidney disease, diabetes, obesity, ovarian cancer, prostate
cancer, hepatocellular carcinoma, and pulmonary fibrosis.

Conclusion:

SET7/9 is an important methyltransferase, which can catalyze the methylation of a variety
of proteins. Its substrates are closely related to the occurrence and development of tumors.
Effects of Nigella Sativa (Black seeds) Supplementation on Plasma Lipid
Profile in Human Subjects - A Review
Authors: Maideen Naina Mohamed Pakkir
Published: December 2021

:

Dyslipidemia is the major risk factor for atherosclerotic cardiovascular disease
(ASCVD), cerebrovascular disease, and peripheral artery disease (PAD). It is characterized by higher
plasma concentrations of total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-c),
apolipoprotein B (apoB), very low-density lipoprotein-cholesterol (VLDL-c), triglycerides (TGs)
and low levels of high-density lipoprotein-cholesterol (HDL-c). Herbal medicines are preferred by
many across the globe particularly to manage chronic conditions such as dyslipidemia, hypertension,
type 2 diabetes, cancer, and plenty of others. Nigella sativa (black seeds or black cumin seeds)
is a miracle herb employed within the management of many sicknesses for centuries. Hence, this
review focuses on the ameliorative effects of N. sativa on the plasma lipid concentrations of human
subjects. Numerous randomized controlled clinical trials (RCTs) and different clinical studies demonstrated
that N. sativa possesses potential anti-dyslipidemic activity. The patients with dyslipidemia
may well be benefited by using N. sativa along with healthy lifestyle changes and statin and
other antihyperlipidemic medications as adjuvant therapy if needed.
Sustainability of ijtihad and fatwa to respond the issue of indirect contributions in matrimonial property claim
Authors: Yusoff Mus’ab , Urus Nur Sarah Tajul , Yusoff Umair , Thahir Mohamad Fauzi Md , Othman Siti Nurul Husna , Zainon Masyitah Mohd , Samsudin Mohd Syahmil bin
Published: December 2021

The issue of sustainability of ijtihad and fatwas to elaborate on polemics of indirect contributions in matrimonial property claims has become an important issue today. The selection of the right ijtihad and fatwa will ensure that critical discussions in this matter can be photographed to a knowledgeable society. Many findings of jurisprudence writing stated the main methods in ijtihad and fatwas used by fuqahak of the past and contemporary to draw interesting discussions on this issue, but in the context of indirect contributions in matrimonial property claims, there is still much to be clarified. The main objective of this study is to find out the method of ijtihad and fatwa in the book of fiqh applied by the jurists in this issue. This study is qualitative in which a total of 20 books of turath have been researched and understood descriptively. The main collection methods used were in-depth reading and analysis and narrative evaluation was used to analyze the findings obtained. The results of the analysis prove that the indirect contribution related to housework and outdoor work, can be done Akad al-Ijarah for the wife is eligible to take a certain wage according to the jumhur view.
Voice and Silence in Jacqueline Woodson’s Brown Girl Dreaming
Authors: Van Lierop-Debrauwer Helma
Published: December 2021

In 2014, the American writer Jacqueline Woodson published Brown Girl Dreaming, the story of her childhood in free verse, which was classified as young adult literature. Most US reviewers characterized and appreciated the book both as a human rights narrative of a young brown girl’s coming of age against the socio-political background of racism and the Civil Rights Movement in the United States of the 1960s, and as a personal history of her development as a writer.

In this article the major focus will be on how Brown Girl Dreaming as both a political memoir and an autobiographical narrative of identity formation is fleshed out. On the basis of my analysis of these two plot lines, I will further argue that its categorization as young adult literature disguises that the novel addresses a dual audience of adult and young readers. In my argumentation related to the political and personal character of the novel, as well as in my discussion of the crossover potential of Brown Girl Dreaming, I will focus on the presence of voice and silence.
Aislamiento de bacterias presentes en la sala de necropsias veterinarias y riesgos para la salud
Authors: Spinelli Perossi Isabela Fernanda , Martinelli Paulo Baptista , Vedovelli Cardoso Marita , De Moraes Julieta Rodini Engracia
Published: December 2021

Objetivo. El objetivo de este estudio fue caracterizar las bacterias de una sala de autopsias veterinarias, su perfil de susceptibilidad antimicrobiana y probar la eficacia de dos desinfectantes frente a estos microorganismos. Materiales y métodos. Tres puntos de la sala en los que los profesionales normalmente no usan equipo de protección personal (EPP) al entrar en contacto directo con estas bacterias. Antes y después de la desinfección con hipoclorito y alquilbencenosulfonato sódico se realizaron recuentos anaeróbicos y aeróbicos mesófilos, luego se identificaron los aislamientos por sus características morfotintoriales y bioquímicas y su susceptibilidad antibiótica. Resultados. Los resultados preliminares indicaron que el hipoclorito fue el agente desinfectante de elección para la desinfección de superficies y contra las bacterias patógenas potenciales aislados más frecuentes como Staphylococcus spp (75%), E. coli y Klebsiella spp (15%) y Pseudomonas spp (10%). Además, el 25.0% de los estafilococos fueron resistentes a al menos un antimicrobiano probado y se tomaron en consideración Klebsiella spp, E. coli y Pseudomonas spp, se observó una amplia resistencia antimicrobiana probada. Conclusiones. La caracterización de estas bacterias encontradas en la sala de autopsias es importante para alertar a los profesionales sobre los riesgos biológicos a los que están expuestos, así como las precauciones que deben tomar.