bluuebunny/crossref_metadata_2025 huggingface dataset:
Prácticas tributarias del sector de transporte pesado en la ciudad de Guaranda
Authors: Morejón-Chata Mayra Janeth , Vera-Loor Rosa Yessenia
Published: September 2022

Las actividades comerciales exigen hoy más que nunca estar al día con los procesos tributarios, sin embargo, el sector de transporte pesado en la ciudad de Guaranda muestra irregularidades en relación a los respectivos documentos que se presentan frente a la administración tributaria, por esta razón, nace la idea de hacer una revisión exhaustiva acerca de este tema, tomando como objeto de estudio a la Compañía Nacional de Transporte de Carga Pesada Bolivarenses S.A Transguaranda. La metodología tiene un enfoque cualitativo, se usó una entrevista abierta como instrumento de validación. De los resultados obtenidos, se evidenció que, la Compañía no cuenta con prácticas tributarias eficientes, puesto que, los socios o accionistas no entregan a tiempo los comprobantes de venta y documentos complementarios en sus puntos de emisión, siendo importante implementar medidas internas que contribuyan a llevar un mejor control de las prácticas tributarias ante el Servicio de Rentas Internas.
Implicancia de las políticas de formación académica en las estrategias didácticas en tiempos de pandemia, Universidad de Guayaquil
Authors: Moscoso-Zamora Víctor , Bricio-Samaniego Karina , Guime-Calero Julio
Published: September 2022

El presente estudio se realizó con el objetivo de valorar la implicancia de la Guía metodológica-académica, Resolución No.R-CIFI-UG-SE24-124-29-05-2021, de la Universidad de Guayaquil en la implementación de estrategias didácticas acordes al contexto áulico en tiempos de pandemia, su impacto en el proceso de enseñanza-aprendizaje, y el nivel de la calidad educativa en la búsqueda de la excelencia académica. El diseño metodológico de investigación tuvo un enfoque cuantitativo e interpretativo, con un alcance descriptivo y explicativo, además, se empleó los métodos; dialéctico, analógico e inferencial. La investigación se realizó en una de las carreras más representativas de la institución. Se recopiló información mediante la técnica encuestas, utilizando la herramienta Google forms, y para la tabulación y contraste de los resultados el Excel, y el software SPSS Statistics. Los resultados estadísticos determinaron los niveles de impacto de la normativa en las estrategias didácticas empleadas, así como, una correlación bilateral directa y significativa, en la interacción entre docentes y estudiantes
Gestión de la calidad del servicio en los restaurantes de cuatro tenedores, estudio de caso Portoviejo
Authors: Loor-Bravo Jessica , Vélez-Moreira Estefanía
Published: September 2022

La presente investigación de tipo mixta, tuvo como objetivo diagnosticar la gestión de la calidad de servicio en los restaurantes de cuatro tenedores de la ciudad de Portoviejo, provincia de Manabí. El enfoque de la investigación fue mixto no experimental, en el que se aplicaron métodos analíticos, descriptivos y exploratorios. A través de una muestra se estableció la población en estudio, constituida por los comensales del establecimiento, con el fin de recolectar datos relevantes sobre la gestión de la calidad de servicio aplicando el modelo ServPerf, así como también entrevistas al personal administrativo y operativo. Este establecimiento de cuatro tenedores tiene varios años brindando servicios de restauración, y es especializado en carnes a la parrilla. Entre otros atributos, posee personal capacitado y certificaciones de calidad debido a las normas de higiene y seguridad que aplican en la cadena de valor del producto. Por otra parte, la aplicación del instrumento de medición de la calidad, permitió establecer tres dimensiones: calidad en la imagen del establecimiento, calidad en el desempeño de los empleados y, por último, calidad en los servicios del restaurante. Con los resultados obtenidos en el análisis FODA se establecieron tres estrategias que responden a las dimensiones evaluadas. La investigación concluyó que el modelo de gestión actual del restaurante La Parrilla de Mosko, debe implementar uno nuevo que potencie la imagen de dicho establecimiento, así como las capacidades y habilidades de sus empleados, que son la clave para generar una óptima calidad de servicio.

Palabras clave: Gestión de la calidad, Test ServPerf, servicio de restauración, calidad de servicio
Educación virtual en tiempos de pandemia desde los actores educativos de la Carrera de Odontología, Cuenca – Ecuador
Authors: Encalada-Verdugo Liliana , Pazmiño-Piedra Juan , Castro-Salazar Ana
Published: September 2022

La pandemia dejo la virtualidad como legado a las nuevas generaciones, las instituciones de educación superior al momento cuentan con plataformas para impartir clases en línea. La presente investigación analiza la capacidad organizativa, pedagógica y tecnológica de la enseñanza - aprendizaje virtual de la carrera de odontología en tiempos de pandemia. El grupo de estudio estuvo conformado por estudiantes matriculados en el periodo académico abril septiembre 2020 y docentes que laboraron en el mismo periodo. Fue un estudio descriptivo de corte trasversal; los instrumentos utilizados obtuvieron un alfa de Cronbach 0.946 y 0.919 para estudiantes y docentes respectivamente. Los resultados obtenidos se cuantificaron en una escala de Likert donde los docentes indicaron que los ejes organizativo, pedagógico y tecnológico en tiempos de pandemia fueron porcentualmente mayores en escala de muy bueno y excelente, mientras que los estudiantes reportan un porcentaje mayor para la escala regular y buena. Se concluye que a pesar que los estudiantes aducen problemas propios del proceso de enseñanza virtual en los diferentes ejes, hay que recalcar la importancia y utilidad de esta modalidad en tiempos de pandemia. Se deben mantener y reforzar los procesos de capacitación docente por parte de la universidad con respecto a las herramientas digitales y realizar asesorías permanentes para los actores educativos.
Analisis Persepsi Guru dan Siswa SDN Pagu 1 Terhadap Efektifitas Pelaksanaan Pembelajaran Daring
Authors: Sajida Aprelita Hana , Thohir M. Anas
Published: September 2022

Abstrak. Pembelajaran daring adalah suatu proses interaksi belajar mengajar antara guru dan siswa secara jarak jauh melalui handphone atau laptop atau media digital lainnya yang sesuai dan menggunakan akses internet secara penuh. Dalam penerapannya, setiap sekolah pastinya memiliki kebijakannya masing-masing. Di SDN Pagu 1, pembelajaran daring dilaksanakan melalui berbagai macam media digital agar siswa tidak mudah bosan. Namun, berdasarkan metode wawancara yang ditujukan kepada guru dan angket terbuka yang ditujukan pada siswa, menunjukkan hasil bahwa pembelajaran daring masih kurang efektif jika diterapkan untuk siswa SD. Adapun tujuan dari penelitian ini adalah untuk mendeskripsikan efektifitas pelaksanaan pembelajaran daring berdasarkan pandangan dari guru dan siswa SDN Pagu 1.Kata Kunci. Pembelajaran Daring, Siswa, Guru
Analisis Penerapan Pembelajaran Tematik Muatan Matematika Materi Membandingkan Berat Benda pada Siswa Kelas II di SDN Turi 2
Authors: Tamara Yunita Dwi , Hidayah Nurul , Budi'ani Maulida Dedek , Yuniawatika Yuniawatika , Mas'ula Siti
Published: September 2022

Abstrak. Peserta didik harus menguasai materi matematika sebagai bentuk penataan nalar dan pengambilan keputusan dalam era persaingan yang semakin kompetitif pada saat ini. Oleh karena itu perlu adanya penerapan pembelajaran matematika yang efektif untuk meningkatkan pemahaman dan kemampuan matematika peserta didik. Tujuan dari penelitian ini adalah untuk menganalisis penerapan pembelajaran tematik muatan matematika materi membandingkan berat benda pada siswa kelas II sekolah dasar. Metode yang digunakan dalam penelitian ini adalah wawancara dan observasi secara langsung kegiatan pembelajaran matematika serta dokumentasi, dengan pendekatan penelitian kualitatif. Subjek penelitiannya adalah 12 siswa kelas II dan seorang guru kelas II di SD Negeri Turi 2. Data yang telah diperoleh dari wawancara dan observasi kemudian dianalisis sehingga diperoleh hasil dan kesimpulan. Kesimpulan dari penelitian ini adalah metode pembelajaran yang digunakan adalah saintifik yang terdapat diskusi, guru menggunakan perangkat pembelajaran berupa alat peraga sederhana yang sesuai dengan materi, dan kendala yang terjadi adalah keterbatasan media pembelajaran yang disediakan sekolah serta kemampuan beberapa siswa yang masih tertinggal jauh dibandingkan siswa yang lain.Kata Kunci. pembelajaran matematika, kelas II sekolah dasar, materi berat benda.
Implementasi Model Pembelajaran Flipped Classroom Guna Meningkatkan Interaksi Belajar Mahasiswa Pada Mata Kuliah Pembelajaran Tematik SD
Authors: Nizhomi Bestiana , Nisa Ana Fitrotun , Pusporini Widowati
Published: September 2022

Abstrak. Penelitian ini dilatar belakangi oleh beberapa permasalahan, diantaranya yaitu  kebijakan  pemerintah  untuk  menerapkan  pembelajaran  daring  di  masa  pandemi  covid  19  yang menimbulkan  beberapa permasalahan seperti, interaksi dosen dan mahasiswa yang kurang baik sehingga membuat kegiatan belajar mengajar cenderung menjadi pasif dan kurang efektif. Pada situasi yang seperti ini, pendidik harus berinovasi dan mengambil tindakan cepat agar pembelajaran  bisa  berjalan efektif kembali. Sebelum pandemi kegiatan belajar biasanya dilakukan di kampus diubah menjadi kegiatan Belajar Di Rumah  (BDR). Salah satu alternatif yang tepat di masa pandemi  ini yaitu penerapan model pembelajaran flipped classroom. Model pembelajaran ini dapat mengkombinasikan antara pembelajaran internal dikelas dengan pembelajaran diluar kelas atau kelas terbalik dengan maksud untuk memaksimalkan kegiatan pembelajaran mata kuliah Pembelajaran Tematik SD. Teknik analisis data yang digunakan dalam penelitian ini adalah kualitatif deskriptif.  Penelitian ini dilakukan bersiklus dengan tahapan tiap siklusnya terdiri dari perencanaan, pelaksanaan, pengamatan dan refleksi. Teknik pengumpulan data dilakukan melalui observasi, dokumentasi dan kuesioner. Hasil penelitian ini menunjukkan bahwa mahasiswa memiliki persepsi positif dalam semua komponen interaksi pembelajaran mata kuliah pembelajaran tematik SD menggunakan model pembelajaran flipped classroom.Kata Kunci: Model Pembelajaran Flipped Classroom, Interaksi Belajar,  Pembelajaran Tematik SD
Efektifitas Penggunaan Google Meeting Pada Pembelajaran Daring Terhadap Pemahaman IPA Siswa Kelas 4 SD
Authors: Marlina Diyan
Published: September 2022

Abstrak. Tujuan dari penelitian ini adalah untuk mendeskripsikan efektivitas google meeting pada pembelajaran daring terhadap pemahaman IPA siswa kelas 4 di SDN Krowe 1. Penelitian ini menggunakan penelitian kuantitatif dengan menggunakan metode True Experimental Design tipe Posttest-only control design. Sampel sebanyak 30 siswa. Teknik pengambilan sampel penelitian ini mengguunakan Cluster Random Sampling. Teknik pengumpulan data pada penelitian ini menggunakan wawancara, tes dan dokumentasi. Teknik analisis  data pada penelitian ini menggunakan statistik dengan tahap uji prasyarat yang terdiri dari uji normalitas, uji homogenitas dan uji hipotesis.  Hasil penelitian ini menunjukkan bahwa thitung  ≥  t tabel  (2.597 ≥2.048)maka Ho di tolak, artinya penggunaan google meeting efektif terhadap pemahaman IPA siswa kelas 4 di SDN Krowe 1.Kata Kunci. Google Meeting, daring, Pemahaman IPA
Implementasi Literasi Digital Era Abad 21 Dalam Membentuk Karakter Peserta Didik MIS Soko Kota Pekalongan
Authors: Musa Muhammad Maskur
Published: September 2022

Abstrak. Indonesia pada Program for International Student Assessment (PISA) menempati urutan ke-57 dari 65 negara yang diteliti dalam hal kemampuan membaca. Tingkat membaca khususnya siswa bisa dikatakan sangat rendah. Rendahnya kemampuan membaca pada siswa maka pengetahuan yang dimiliki juga akan mengalami ketertinggalan. Rendahnya tingkat membaca di kalangan siswa ini menjadi perhatian khusus bagi pemerintahan yang bersangkutan yaitu kementerian pendidikan dan kebudayaan. Di zaman sekarang perkembangan teknologi yang semakin maju dan pesat membuat segala kehidupan manusia membutuhkan sebuah teknologi yang berbasis digital. Perkembangan teknologi ini juga membuat kemudahan dalam mendapatkan segala informasi. Sehingga hal ini dimanfaatkan oleh kementerian pendidikan dan kebudayaan di bidang pendidikan yaitu salah satunya gerakan literasi yang memanfaatkan teknologi. Tujuan penelitian ini untuk mendekripsikan mengenai implementasu literasi digital era abad 21 dalam membentuk karakter peserta didik MIS Soko Kota Pekalongan. Metode penelitian ini menggunakan kualitatif deskriptif, pengumpulan datanya melalui kegiatan observasi, wawancara dan dokumentasi. Hasil penelitian menjelaskan bahwa literasi digital ini sudah diterapkan di MIS Soko Kota Pekalongan terutama dalam membentuk katrakter peserta didik. Apalagi 2 tahun kemarin seluruh dunia merebak penyakit yang bernama covid 19 semua aktivitas manusia menjadi berubah, salah satunya di pendidikan yang tadinya proses pembelajaran di MIS Soko Kota Pekalongan tatap muka menjadi pembelajaran daring. Hal ini menjadi sebab literasi digital diterapkan di MIS Soko Kota Pekalongan dalam membentuk karakter. Karakter yang dibentuk seperti kejujuran, kedisiplinan, kreatif dan berpikir kritis.Kata kunci: Literasi Digital, Karakter, Peserta Didik
Profil Berpikir Probabilistik dalam Pemecahan Materi Peluang Kejadian Berdasarkan Self-efficacy
Authors: Shodiqin Ali , Nuraini Aurora , Wulandari Dewi
Published: September 2022

Di era modern ini diperlukan kemampuan berpikir. Seseorang yang menghadapai masalah ketidakpastian dalam berpikir probabilisik memerlukan banyak pertimbangan untuk memutuskan keputusan. Pemecahan masalahan probabilistik merupakan bagian berpikir tingkat tinggi, karena diperlukan banyak pertimbangan. Tujuan penelitin adalah untuk mendeskripsikan kemampuan berpikir probabilistik calon guru matematika dalam pemecahan masalah probabilistik berdasarkan perspektif self-efficacy. Penelitian ini adalah penelitian kualitatif diskriptif dengan subjeknya dari mahasiswa matematika berdasarkan kemampuan self-efficacy tinggi, sedang dan rendah, dengan instrument penelitian berupa angket self-efficacy, tes tulis dan pedoman wawancara. Teknik analisis data dari hasil tes tertulis dan hasil wawancara ditarik kesimpulan dengan mengikuti proses: (1) reduksi data, (2) sajian data; dan (3) penarikan kesimpulan dan verifikasi. Berdasarkan hasil analisis berpikir probabilistik didapatkan subjek self-efficacy tinggi untuk materi ruang sampel di level numerik, dan materi kejadian dan probabilistik di level kuantitatif informal cenderung ke level  numerik. Subjek self-efficacy tengah untuk materi ruang sampel di level numerik, dan materi kejadian dan probabilistik di level subjektif. Subjek self-efficacy rendah untuk materi ruang sampel berada level subjektif, dan materi kejadian dan probabilistik di level subjektif cenderung ke level transional.Kata Kunci: berpikir probabilistik, pemecahan masalah, self-efficacy
Pengembangan E-Modul Aljabar Linear Dengan Pendekatan Pendidikan Matematika Realistik Berbasis Nilai-Nilai Keislaman
Authors: Wulantina Endah
Published: September 2022

Abstrak. Pembelajaran matematika tidak hanya menghasilkan mahasiswa yang berhasil dalam perhitungan matematis dan prosedural, tetapi juga mengembangkan pemikiran religius. Oleh karena itu perlu adanya integrasi nilai-nilai agama ke dalam proses pembelajaran. Untuk meningkatkan pedagogis mahasiswa, perlu dilakukan integrasi pendekatan pendidikan matematika realistik dengan lesson study. Selama pandemi covid 19 pembelajaran dilakukan full online. Untuk itu perlu adanya referensi modul perkuliahan berbentuk digital. Tujuan dari penelitian ini adalah mengembangkan e-modul aljabar linear dengan pendekatan pendidikan matematika realistik berbasis nilai-nilai keislaman pada materi matriks dan sistem persamaan linear.  Jenis penelitian yang digunakan adalah penelitian dan pengembangan (R&D) dengan mengikuti model PPE (Planning, Production, Evaluation). Validasi dilakukan oleh ahli materi matematika, ahli media dan ahli agama. Instrumen yang digunakan yaitu lembar validasi angket dan lembar respon mahasiswa. Berdasarkan penelitian diperoleh validasi ahli materi matematika memperoleh skor rata-rata sebesar 3,9 dengan kategori valid, hasil validasi ahli materi agama islam mendapatkan skor rata-rata 3,8 dengan kategori valid, hasil dari validasi media mendapatkan skor 3,55 dengan kategori valid.  Hasil perhitungan respon mahasiswa mendapatkan persentase skor pada aspek tampilan sebesar 81% dengan kriteria sangat menarik, persentase skor pada aspek penyajian isi sebesar 84% dengan kriteria menarik, persentase skor pada aspek kemenarikan sebesar 83% dengan kriteria sangat menarik. Katakunci: e-modul, nilai-nilai keislaman, pendidikan matematika realistik
Analisis ketertarikan guru matematika dengan kerangka PIECES terhadap penggunaan software flip pdf profesional
Authors: Harisman Yulyanti , Taufik Iqbal , Suherman Suherman , Resmi Darni , Noto Muchamad Subali
Published: September 2022

Abstrak. Proses pembelajaran pada masa pandemi COVID-19 dilakukan secara daring (dalam jaringan), sehingga perlu dilakukan inovasi bahan ajar berbasis teknologi yang dapat membantu peserta didik belajar di rumah. Sebagai dampak dari hal tersebut guru harus dibekali dengan pelatihan-pelatihan yang terkait dengan Technological Pedagogical dan Content Knowledge (TPACK) dalam pengembangan bahan ajar. Namun, yang menjadi pertanyaan, apakah guru tertarik untuk mengikuti pelatihan tersebut, untuk itu perlu dilakukan sebuah survey untuk meninjau sejauh mana ketertarikan guru terhadap pelatihan untuk peningkatan TPACK. Penelitian ini bertujuan untuk melihat ketertarikan guru dengan kerangka PIECES terhadap penggunaan software flip pdf profesional dalam mengembangkan bahan ajar berbasis TPACK. Penelitian survey dilakukan dengan subjek penelitian adalah guru matematika Sekolah Menengah Pertama (SMP) se-kota Padang. Tiga puluh guru matematika dari 24 SMP diberikan pelatihan mengenai aplikasi ini selama enam minggu. Pelatihan diberikan kepada guru mulai dari pengenalan software, penggunaan menu, pembuatan bahan ajar, dan publish online. Setelah pelatihan guru diberikan angket dengan domain kerangka PIECES. Berdasarkan hasil analisis data diperoleh kesimpulan bahwa guru menunjukkan ketertarikan terhadap aplikasi flip pdf profesional dengan tingkat kepuasan tinggi dan menganggap pelatihan yang diberikan adalah penting.Kata Kunci: Flip Pdf Professional, Pembelajaran Daring, PIECES Framework
Model CTL dan Online Learning: Dapatkan Berdampak Bagi Koneksi dan Disposisi Matematis Siswa SD?
Authors: Yuliana Dwi , Widyasari Nurbaiti
Published: September 2022

Abstrak. Rendahnya kemampuan koneksi dan kondisi pandemi yang memaksa pembelajaran daring menjadi latar belakang penelitian ini menggunakan model CTL yang berkaitan dengan kehidupan sekitar siswa. Tujuan penelitian ini adalah untuk meningkatkan kemampuan koneksi dan disposisi matematis melalui penerapan model Contextual Teaching dan Learning (CTL) yang disesuaikan dengan kondisi pembelajaran daring menggunakan grup Whatsapp dan Zoom Meeting. Metode penelitian yang digunakan adalah penelitian kuasi eksperimen dengan desain one group pretest-posttest. Sampel dalam penelitian ini adalah sebanyak 26 siswa kelas 4 dengan menggunakan teknik purposive sampling di salah satu sekolah di Bekasi. Instrumen yang digunakan dalam penelitian ini adalah tes kemampuan koneksi dan angket disposisi. Uji hipotesis yang digunakan adalah uji t paired dengan menggunakan SPSS 21. Hasil penelitian menunjukkan peningkatan kemampuan matematis dan disposisi matematis dari sebelum dan sesudah diterapkan CTL. Dapat disimpulkan bahwa penerapan model CTL dapat digunakan untuk meningkatkan kemampuan koneksi dan disposisi matematis di pembelajaran daring.Kata Kunci: contextual teaching dan learning, disposisi matematis, koneksi matematis.
Microplastic Occurrence in the Gill and Gastrointestinal Tract of Chelon ramada (Mugilidae) in a Highly Urbanized Region, İskenderun Bay, Türkiye
Authors: KILIÇ Ece
Published: September 2022

Microplastic pollution in marine ecosystems has become a significant, global concern which attracting the attention of academics and policy makers. This study provides information regarding the microplastic occurrence in the gill and gastrointestinal tract (GIT) of Chelon ramada (Risso, 1827). A total of 158 MPs were extracted from the gill and GIT with a mean of 1.9±1.8 particle/individual in gill and 3.4±2.1 particle/individual in GIT. Fiber was the most commonly extracted microplastic type (79%), followed by fragments (16%), film (4%) and pellet (2%). Mean size of extracted MPs from the organs of Chelon ramada was found as 1251±1602 µm. Black, transparent, red and blue MPs were extracted from the organs and dominance of black and transparent MPs were observed in the gill and GIT, respectively. This study is providing the first data regarding the microplastic ingestion of Chelon ramada and the results obtained in this will help to understand the relationship between anthropogenic influences and microplastic ingestion.
Why Do Populist Governments Change Their Policies: Evidence from Turkey
Authors: Arslantas Duzgun
Published: September 2022

This paper highlights the changing populist character of the Justice and Development Party (Adalet ve Kalkınma Partisi or AKP) since it captured power in 2002. It posits that the AKP’s dominant form of populism has changed from being “inclusionary” to “exclusionary” over time. More specifically, the AKP leadership initially adopted inclusionary populism to overcome the threat of party closure and extend its voter base. As the economic downturn began to shrink clientelist resources from the second term onwards, however, the AKP has shifted towards exclusionary populism that was based on the extension of polarization along religious and ethnic lines. Such transition well overlaps with the authoritarian transition in recent years.
ХУДОЖНЬО-СТИЛЬОВІ ОСОБЛИВОСТІ ТУРИСТИЧНОГО ПЛАКАТА БАЛКАНСЬКИХ КРАЇН
Authors: Pryshchenko Svitlana
Published: September 2022

Комунікативний підхід до візуальної мови плаката розкрито на прикладі туристичної реклами. Крос-культурна взаємодія нині особливо актуальна у зв’язку із розширенням інформаційного простору, культурно-мистецьким розвитком, посиленням євроінтеграційних процесів. Для реалізації мети дослідження використано системно-структурний, історико-мистецтвознавчий, компаративний і соціокультурний методи. Наукова новизна статті полягає в проведенні аналізу засобів візуалізації і художньо-стильових особливостей туристичного плаката Балканських країн другої половини ХХ – другого десятиліття ХХІ ст. З’ясовано, що візуальне мислення в рекламі ґрунтується на художньо-графічній майстерності, прийомах образотворення, стилістиці, притаманних європейському мистецтву: декоративізму, попарту, постмодернізму. Окреслено перспективи розвитку туристичного плаката з урахуванням новітніх тенденцій.
СПРИЙНЯТТЯ ТВОРІВ ДЕКОРАТИВНОГО МИСТЕЦТВА У КОНТЕКСТІ АРХІТЕКТУРНО-ХУДОЖНЬОГО ФОРМУВАННЯ ВНУТРІШНЬОГО СЕРЕДОВИЩА БУДІВЕЛЬ ЦИВІЛЬНОГО ПРИЗНАЧЕННЯ
Authors: Cherniavskyi Volodymyr
Published: September 2022

У статті проаналізовано особливості сприйняття творів декоративного мистецтва під час архітектурно-художнього формування внутрішнього середовища цивільних будівель. На підставі проведених наукових досліджень та виконаних практичних робіт у процесі комплексного формування інтер’єрів розроблено основні архітектурно-художні прийоми розміщення творів декоративного мистецтва у внутрішньому середовищі будівель, що суттєво поліпшить їхнє сприйняття у внутрішньому просторі.
ЩОДО ПРОБЛЕМИ ІКОНОГРАФІЧНОГО ПРОТОТИПУ НАРОДНОЇ КАРТИНИ «ОЛЕНКА І ОЛЕНЬ»
Authors: Denysiuk Olha , Derevska Olena
Published: September 2022

Статтю присвячено пошукові іконографічного прототипу народної картини «Оленка і олень» (або «Дівчина з оленем»), сюжет якої – один з найпоширеніших у народному мистецтві, проте не досить вивчений. Сюжетне розмаїття українського народного живопису ХХ ст. вимагає від дослідників визначення іконографічних прототипів цілої низки сюжетів народних картин, зокрема й твору «Оленка і олень».
УКРАЇНСЬКЕ МИСТЕЦТВО В ОБРАЗАХ ТА ПЕРСОНАЛІЯХ ХХ – ПОЧАТКУ ХХІ СТ.
Authors: Mykhailova Rada
Published: September 2022

УКРАЇНСЬКЕ МИСТЕЦТВО В ОБРАЗАХ ТА ПЕРСОНАЛІЯХ ХХ – ПОЧАТКУ ХХІ СТ.
Energy requirements of Holstein, Gyr, and Holstein × Gyr crossbred heifers using the respirometry technique
Authors: Silvestre Taina , Ferreira Alexandre Lima , Machado Fernanda Samarini , Campos Mariana Magalhaes , Tomich Thierry Ribeiro , Pereira Luiz Gustavo Ribeiro , Rodrigues Paulo Henrique Mazza , Marcondes Marcos Inacio
Published: September 2022

We aimed to determine the energy requirements for maintenance and gain of 18 prepubertal dairy heifers of three breed compositions (BC; Holstein, Gyr, and Holstein × Gyr). Diets were formulated for gains of 0, 400, and 800 g/day, corresponding to 1.0×, 1.5×, and 2.0× maintenance, respectively. Each dairy BC had six animals with an initial body weight (iBW) of 219.8 ± 32 kg, 215.8 ± 33 kg, and 228.3 ± 33 kg for Holstein, Gyr, and Holstein × Gyr, respectively. The experiment was designed as a completely randomized design in a factorial scheme 3 × 3 [three BC and three feeding levels (FL)]. Digestibility and metabolism assays were performed to determine energy losses through feces and urine. Heat production was determined using the continuous measurement of oxygen consumption, carbon dioxide production, and methane emissions in respiration chambers. Energy requirements for maintenance (NEm) were calculated based on the relationship between heat production (HP) and metabolizable energy intake (MEI). The efficiency of use of metabolizable energy for maintenance (km) was obtained from the ratio between NEm and metabolizable energy requirements for maintenance. The net energy requirements for growth (NEg) were estimated from the model RE = β0 × EBW0.75 × EBGβ1, where RE is the retained energy (Mcal/day), EBW is empty body weight (kg0.75), and EBG is the empty body gain (kg/day). The efficiency of use of metabolizable energy for gain (kg) was estimated as the slope of the regression between RE and MEI for gain. Gyr heifers presented NEm 15% lower (98 kcal/kg of BW0.75) than HG crossbred animals. Holstein and crossbred heifers had similar NEm, 102 and 112 kcal/kg of BW0.75, respectively. The km was 0.71, 0.74, and 0.75 for HG, Holstein, and Gyr, respectively. Net energy requirement for gain (NEg) did not differ across BC, and a single equation was fit for all BC: RE = 0.069 × BW0.75 × BGW0.852. A single kg of 0.65 was observed for all three BC. Breed composition affected the energy requirements for maintenance and the energy partition, and those differences should be considered when estimating requirements for Gyr, Holstein × Gyr crossbred, and Holstein heifers.
Overcoming technological barriers in microfluidics: Leakage testing
Authors: Silverio Vania , Guha Suvajyoti , Keiser Armelle , Natu Rucha , Reyes Darwin R. , van Heeren Henne , Verplanck Nicolas , Herbertson Luke H.
Published: September 2022

The miniaturization of laboratory procedures for Lab-on-Chip (LoC) devices and translation to various platforms such as single cell analysis or Organ-on-Chip (OoC) systems are revolutionizing the life sciences and biomedical fields. As a result, microfluidics is becoming a viable technology for improving the quality and sensitivity of critical processes. Yet, standard test methods have not yet been established to validate basic manufacturing steps, performance, and safety of microfluidic devices. The successful development and widespread use of microfluidic technologies are greatly dependent on the community’s success in establishing widely supported test protocols. A key area that requires consensus guidelines is leakage testing. There are unique challenges in preventing and detecting leaks in microfluidic systems because of their small dimensions, high surface-area to volume ratios, low flow rates, limited volumes, and relatively high-pressure differentials over short distances. Also, microfluidic devices often employ heterogenous components, including unique connectors and fluid-contacting materials, which potentially make them more susceptible to mechanical integrity failures. The differences between microfluidic systems and traditional macroscale technologies can exacerbate the impact of a leak on the performance and safety on the microscale. To support the microfluidics community efforts in product development and commercialization, it is critical to identify common aspects of leakage in microfluidic devices and standardize the corresponding safety and performance metrics. There is a need for quantitative metrics to provide quality assurance during or after the manufacturing process. It is also necessary to implement application-specific test methods to effectively characterize leakage in microfluidic systems. In this review, different methods for assessing microfluidics leaks, the benefits of using different test media and materials, and the utility of leakage testing throughout the product life cycle are discussed. Current leakage testing protocols and standard test methods that can be leveraged for characterizing leaks in microfluidic devices and potential classification strategies are also discussed. We hope that this review article will stimulate more discussions around the development of gas and liquid leakage test standards in academia and industry to facilitate device commercialization in the emerging field of microfluidics.
The ambivalent nature of the relationship between lymphatics and cancer
Authors: Choi Joshua , Choi Ellie , Choi Dongwon
Published: September 2022

Do lymphatic vessels support cancer cells? Or are they vessels that help suppress cancer development? It is known that the lymphatic system is a vehicle for tumor metastasis and that the lymphangiogenic regulator VEGF-C supports the tumor. One such role of VEGF-C is the suppression of the immune response to cancer. The lymphatic system has also been correlated with an increase in interstitial fluid pressure of the tumor microenvironment. On the other hand, lymphatic vessels facilitate immune surveillance to mount an immune response against tumors with the support of VEGF-C. Furthermore, the activation of lymphatic fluid drainage may prove to filter and decrease tumor interstitial fluid pressure. In this review, we provide an overview of the dynamic between lymphatics, cancer, and tumor fluid pressure to suggest that lymphatic vessels may be used as an antitumor therapy due to their capabilities of immune surveillance and fluid pressure drainage. The application of this potential may help to prevent tumor proliferation or increase the efficacy of drugs that target cancer.
The crucial role of cardiac MRI parameters in the prediction of outcomes in acute clinically suspected myocarditis: A functional and feature-tracking study
Authors: Motevalli Marzieh , Asadian Sanaz , Khademi Foroogh , Rezaeian Nahid , Shayan Leila
Published: September 2022

Background

The definitive diagnosis of myocarditis is made by endomyocardial biopsy, but it is an invasive method. Recent investigations have proposed that cardiac MRI parameters have both diagnostic and prognostic roles in assessing myocarditis. We aimed to evaluate the role of functional and feature-tracking (FT)-derived strain values in predicting major adverse cardiovascular events (MACE) in patients with acute myocarditis.

Methods and results

We evaluated 133 patients with acute myocarditis (74.4% men) between January 2016 and February 2021. During a mean follow-up of 31 ± 16 months, sixteen patients (12.03%) experienced MACE: three deaths (2.3%), nine ICD implantations (6.76%), and five cardiac transplantations (3.8%). The left ventricular ejection fraction (LVEF), the LV end-diastolic volume index (EDVI), and the LV global longitudinal strain (GLS) were the strongest predictors of MACE. Each 1-unit decline in LVEF and LVGLS or 1-unit rise in LVEDVI resulted in a 5, 24, and 2% increase in MACE, respectively. LVEF ≤36.46% and LVGLS ≤9% indicated MACE with 75% sensitivity and 74.4 and 73.5% specificity, respectively.

Conclusions

In a group of acute myocarditis patients with evidence of myocardial edema and late Gadolinium enhancement, LVEF and GLS were the strongest predictors of adverse cardiac events.
Case report: Bi-atrial thrombus after occlusion of atrial septal defect with acute cerebral infarction and pulmonary embolism
Authors: Xiong Wei , Tang Li , Long Wei , Liu Jin , Song Haibo
Published: September 2022

A 49-year-old man presented to the hospital with symptoms of acute cerebral infarction and pulmonary embolism who underwent transcatheter closure of atrial septal defect a year before. Transthoracic echocardiography showed a 13 × 9 mm hypoechoic mass attached to the left-atrial side of the device, which was suspected to be a neoplasm or thrombus. The patient was indicated for surgery after multidisciplinary discussion due to ineffective medical therapy and typical stroke and pulmonary embolism symptoms. Three-dimensional transesophageal echocardiography (3D-TEE) revealed left-atrial vegetation (21 × 16 mm) and right-atrial vegetation (8 × 6 mm) attached to the device, which was confirmed as thrombus by surgical separation and laboratory examination. This case highlights the importance of 3D-TEE and a multidisciplinary team in the diagnosis and therapy of device-related thrombus.
Establishment of landslide early-warning indicator using the combination of numerical simulations and case matching method in wushan open-pit mine
Authors: Zhang Penghai , Deng Wenxue , Liu Feiyue , Wang He , Dong Xin , Niu Peng
Published: September 2022

Landslides seriously threaten the safety of human life and property. In order to predict the on-set of potential landslides, this paper first characterizes the physical and mechanical parameters of rock mass on the basis of core rock quality designation identification, the geostatistics interpolation method, and the Hoek-Brown criterion. Then, the rock-mass physical and mechanical parameters characterization model was transformed to the slope numerical models, and the characteristics of potential landslides were predicted combined with the monitoring data and numerical simulation. Finally, on the basis of pairing between potential- and historical landslide cases, an early-warning indicator of a potential landslide was set as a posterior indicator of a historical landslide with the highest similarity. The results show that the potential landslide mode of the west and the southwest slope of the Wushan open-pit mine, the case study considered here, was a single-step wedge landslide and an integral-incline landslide. These two types of landslides were found to be most similar to those in the Anjialing open-pit mine and the Fushun West open-pit mine. Based on the posterior-warning indicator of the most similar landslide cases, the warning indicators of the west and southwest slope are set as 12.7 mm/d and 135.2 mm/d. The proposed method here provides a reference for the establishment of early-warning indicators for landslides in open-pit mines.
A new framework for short-term wind power probability forecasting considering spatial and temporal dependence of forecast errors
Authors: Sun Yong , Li Baoju , Hu Wenhui , Li Zhenyuan , Shi Chaoyu
Published: September 2022

Since deterministic prediction errors of wind power cannot be avoided, probabilistic prediction can adequately describe the uncertainty of wind power and, thus, provide further guidance to dispatching authorities for decision making. Current probabilistic prediction methods for wind power are still incomplete in mining its physical variation process. Therefore, this study constructs a new framework for short-term wind power probabilistic forecasting considering the spatio-temporal dependence of errors by mining the spatio-temporal characteristics of historical wind power data and numerical weather forecasts at numerical weather prediction (NWP). First, the deterministic prediction results are obtained by an improved deep belief network (DBN); then, a multi-location NWP is introduced to propose a multi-level error scenario partitioning method considering the spatio-temporal dependence property. Finally, a new error sample set is formed by reconstructing the kernel density estimation method to adapt the model, and the short-term wind power probability prediction at different confidence levels is carried out. It is, thus, concluded that the effectiveness of the overall framework under the probabilistic prediction considering spatio-temporal dependence is verified in a wind farm in Jilin, China, and the prediction accuracy is effectively and significantly improved compared with the same confidence level, and the coverage of the evaluation index prediction interval is improved by 1.23, 0.72, and 0.80%, and the average bandwidth of the prediction interval is reduced by 2.14, 1.40, and 0.63%, which confirms the proposed effectiveness and feasibility of the method.
Adaptive fault-tolerant control of five-phase permanent magnet synchronous motor current using chaotic-particle swarm optimization
Authors: Chen Chaobo , Song Ye , Zhang Youmin , Tian Jiaqiang , Gao Song , Lang Baohua
Published: September 2022

Both torque ripple and current harmonics are enlarged due to single-phase open-circuit fault of five-phase permanent magnet synchronous motor (FPMSM). Based on chaotic-particle swarm, an adaptive optimization fault tolerant control algorithm is proposed for the FPMSM current. First, Park and Clarke matrices are modified in coordinate transformation process. A reduced-order decoupling matrix is obtained under the open-circuit fault of FPMSM stator winding. Second, the fault-tolerant current is generated with the principle of constant magnetomotive force. Third, the current is adaptively optimized using chaotic-particle swarm algorithm. Hence, motor torque and motor current keep uniform steady state and dynamic performance with them in regular operation. Finally, numerical simulations are carried out to verify the effectiveness of the developed method.
Impact of different straw treatment methods on agricultural production efficiency: An empirical evidence of Jiangsu Province of China
Authors: Chen Huan , Elahi Ehsan , Lei Xinyuan
Published: September 2022

Using county-level panel data collected from Jiangsu Province of China, this study applies the Super-SBM model to investigate the impact of straw retention subsidy and straw burning on agricultural production efficiency. The results found that the agricultural efficiency measurement system with cultivated land quality is more realistic. Agricultural development in the southern part of Jiangsu Province is at the expense of the environment. Straw burning in the open field can significantly improve the efficiency of traditional agricultural production. Moreover, it is found that the straw retention subsidy cannot improve efficiency directly, but it can inhibit straw burning from technical substitution and policy effects. The subsidy may work better when it is applied to local conditions. Moreover, to improve technical efficiency, it is suggested that government should pay attention to both operation training and supervision systems when promoting straw returning technology. In the long run, it is imperative to optimize the comprehensive utilization structure of straws and broaden the range of straw utilization. The findings of the study have broad implications for other agrarian regions with similar issues.
CRISPR/Cas genome editing improves abiotic and biotic stress tolerance of crops
Authors: Li Yangyang , Wu Xiuzhe , Zhang Yan , Zhang Qiang
Published: September 2022

Abiotic stress such as cold, drought, saline-alkali stress and biotic stress including disease and insect pest are the main factors that affect plant growth and limit agricultural productivity. In recent years, with the rapid development of molecular biology, genome editing techniques have been widely used in botany and agronomy due to their characteristics of high efficiency, controllable and directional editing. Genome editing techniques have great application potential in breeding resistant varieties. These techniques have achieved remarkable results in resistance breeding of important cereal crops (such as maize, rice, wheat, etc.), vegetable and fruit crops. Among them, CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR-associated) provides a guarantee for the stability of crop yield worldwide. In this paper, the development of CRISRR/Cas and its application in different resistance breeding of important crops are reviewed, the advantages and importance of CRISRR/Cas technology in breeding are emphasized, and the possible problems are pointed out.
Haplotype-specific chromatin looping reveals genetic interactions of regulatory regions modulating gene expression in 8p23.1
Authors: Saint Just Ribeiro Mariana , Tripathi Pulak , Namjou Bahram , Harley John B. , Chepelev Iouri
Published: September 2022

A major goal of genetics research is to elucidate mechanisms explaining how genetic variation contributes to phenotypic variation. The genetic variants identified in genome-wide association studies (GWASs) generally explain only a small proportion of heritability of phenotypic traits, the so-called missing heritability problem. Recent evidence suggests that additional common variants beyond lead GWAS variants contribute to phenotypic variation; however, their mechanistic underpinnings generally remain unexplored. Herein, we undertake a study of haplotype-specific mechanisms of gene regulation at 8p23.1 in the human genome, a region associated with a number of complex diseases. The FAM167A-BLK locus in this region has been consistently found in the genome-wide association studies (GWASs) of systemic lupus erythematosus (SLE) in all major ancestries. Our haplotype-specific chromatin interaction (Hi-C) experiments, allele-specific enhancer activity measurements, genetic analyses, and epigenome editing experiments revealed that: 1) haplotype-specific long-range chromatin interactions are prevalent in 8p23.1; 2) BLK promoter and cis-regulatory elements cooperatively interact with haplotype-specificity; 3) genetic variants at distal regulatory elements are allele-specific modifiers of the promoter variants at FAM167A-BLK; 4) the BLK promoter interacts with and, as an enhancer-like promoter, regulates FAM167A expression and 5) local allele-specific enhancer activities are influenced by global haplotype structure due to chromatin looping. Although systemic lupus erythematosus causal variants at the FAM167A-BLK locus are thought to reside in the BLK promoter region, our results reveal that genetic variants at distal regulatory elements modulate promoter activity, changing BLK and FAM167A gene expression and disease risk. Our results suggest that global haplotype-specific 3-dimensional chromatin looping architecture has a strong influence on local allelic BLK and FAM167A gene expression, providing mechanistic details for how regional variants controlling the BLK promoter may influence disease risk.
Modulation of miR-429 during osmotic stress in the silverside Odontesthes humensis
Authors: Pagano Antônio D. , Barreto Bruna F. , Domingues William B. , Silveira Tony L. R. , Nunes Leandro S. , Blodorn Eduardo B. , Dellagostin Eduardo N. , Remião Mariana H. , Robaldo Ricardo B. , Campos Vinicius F.
Published: September 2022

Silverside fish inhabit marine coastal waters, coastal lagoons, and estuarine regions in southern South America. Although silversides are not fully adapted to freshwater, they can tolerate a wide range of salinity variations. MicroRNAs (miRNAs) are a class of ∼22 nucleotide noncoding RNAs, which are crucial regulators of gene expression at post-transcriptional level. Current data indicate that miRNAs biogenesis is altered by situations of environmental stress, thereby altering the expression of target mRNAs. Foremost, the silversides were acutely exposed to 30 g.L−1 of salt to reveal in which tissue miR-429 could be differentially expressed. Thus, fish were acclimated to freshwater (0 g.L−1) and to brackish water (10 g.L−1), and then exposed to opposite salinity treatment. Here, we reveal that miR-429, a gill-enriched miRNA, emerges as a prime osmoregulator in silversides. Taken together, our findings suggest that miR-429 is an endogenous regulator of osmotic stress, which may be developed as a biomarker to assist silverside aquaculture.
Predicting prognosis and immunotherapy response among colorectal cancer patients based on a tumor immune microenvironment-related lncRNA signature
Authors: Hu Chuling , Cai Du , Zhong Min-Er , Fan Dejun , Li Cheng-Hang , Lv Min-Yi , Huang Ze-Ping , Wang Wei , Wu Xiao-Jian , Gao Feng
Published: September 2022

Long non-coding RNAs (lncRNAs) remodel the tumor immune microenvironment (TIME) by regulating the functions of tumor-infiltrating immune cells. It remains uncertain the way that TIME-related lncRNAs (TRLs) influence the prognosis and immunotherapy response of colorectal cancer (CRC). Aiming at providing survival and immunotherapy response predictions, a CRC TIME-related lncRNA signature (TRLs signature) was developed and the related potential regulatory mechanisms were explored with a comprehensive analysis on gene expression profiles from 97 immune cell lines, 61 CRC cell lines and 1807 CRC patients. Stratifying CRC patients with the TRLs signature, prolonged survival was observed in the low-risk group, while the patients in the high-risk group had significantly higher pro-tumor immune cells infiltration and higher immunotherapy response rate. Through the complex TRLs-mRNA regulation network, immunoregulation pathways and immunotherapy response pathways were found to be differently activated between the groups. In conclusion, the CRC TRLs signature is capable of making prognosis and immunotherapy response predictions, which may find application in stratifying patients for immunotherapy in the bedside.
Community structure and ecological quality assessment of macrobenthos in the coastal sea areas of Northern Yantai, China
Authors: Li Fan , Ma Yuanqing , Song Xiukai , Li Shaowen , Zhang Xiaomin , Wang Xiuxia , Wang Tiantian , Sun Zhenning
Published: September 2022

Four cruises in the Bohai Sea and northern Yellow Sea off Yantai, China, in April and August of 2020, collected data on the species composition and community structure characteristics of macrobenthos in these sea areas. Temporal and spatial changes in the dominant macrobenthic species between April and August were also analyzed. The M-AMBI and environmental data were used to assess the benthic ecological quality of the coastal waters off Yantai. The results revealed differences in macrobenthic community structure and ecological quality status between the two sea areas. The main findings are as follows: A total of 7 phyla and 153 macrobenthic species were collected; 113 and 101 species were recorded in the Bohai Sea and northern Yellow Sea areas, respectively, and estimated abundance was 301 ind. m-2 and 598 ind. m-2 (p < 0.01), and biomass was 10.20 g m-2 and 14.65 g m-2, respectively. The dominant species comprised small-sized polychaetes and bivalves. The main dominant species were Glycinde bonhourei, Micronephthys oligobranchia, Sternaspis chinensis, and Moerella hilaris. The number of species differed significantly between seasons (p < 0.05). A comparison of the dominant species and community structure of the macrobenthos between seasons showed that more obvious replacement occurred in the Bohai Sea. There were major differences in community structure of the macrobenthos between the two areas. Macrobenthos abundance was positively correlated with depth, dissolved oxygen, and sand substrate, and negatively correlated with bottom-water temperature, pH, and fine silt or clay substrate. In April, sites with low ecological value were at the ports of Laizhou and Longkou and Yangma Island, with the water quality likely affected by intensive bivalve aquaculture, port activities, and river discharge; in August, low-ecological-value sites were the middle of Laizhou Bay, Longkou Port, west of Daheishan Island, and coastal water between the cities of Yantai and Weihai. Overall, the sea areas off Yantai were generally deemed to be in a “good” state of ecological quality.