bluuebunny/crossref_metadata_2025 huggingface dataset:
Differential expression of miR-184 in temporal lobe epilepsy patients with and without hippocampal sclerosis – Influence on microglial function
Authors: Danis Bénédicte , van Rikxoort Marijke , Kretschmann Anita , Zhang Jiong , Godard Patrice , Andonovic Lidija , Siegel Franziska , Niehusmann Pitt , Hanon Etienne , Delev Daniel , von Lehe Marec , Kaminski Rafal M. , Pfeifer Alexander , Foerch Patrik
Published: September 2016

Epilepsy is one of the most common neurological disorders characterized by recurrent seizures due to neuronal hyperexcitability. Here we compared miRNA expression patterns in mesial temporal lobe epilepsy with and without hippocampal sclerosis (mTLE + HS and mTLE −HS) to investigate the regulatory mechanisms differentiating both patient groups. Whole genome miRNA sequencing in surgically resected hippocampi did not reveal obvious differences in expression profiles between the two groups of patients. However, one microRNA (miR-184) was significantly dysregulated, which was confirmed by qPCR. We observed that overexpression of miR-184 inhibited cytokine release after LPS stimulation in primary microglial cells, while it did not affect the viability of murine primary neurons and primary astrocytes. Pathway analysis revealed that miR-184 is potentially involved in the regulation of inflammatory signal transduction and apoptosis. Dysregulation of some the potential miR-184 target genes was confirmed by qPCR and 3′UTR luciferase reporter assay. The reduced expression of miR-184 observed in patients with mTLE + HS together with its anti-inflammatory effects indicate that miR-184 might be involved in the modulation of inflammatory processes associated with hippocampal sclerosis which warrants further studies elucidating the role of miR-184 in the pathophysiology of mTLE.
Ultra-stable clock laser system development towards space applications
Authors: Świerad Dariusz , Häfner Sebastian , Vogt Stefan , Venon Bertrand , Holleville David , Bize Sébastien , Kulosa André , Bode Sebastian , Singh Yeshpal , Bongs Kai , Rasel Ernst Maria , Lodewyck Jérôme , Le Targat Rodolphe , Lisdat Christian , Sterr Uwe
Published: September 2016

The increasing performance of optical lattice clocks has made them attractive for scientific applications in space and thus has pushed the development of their components including the interrogation lasers of the clock transitions towards being suitable for space, which amongst others requires making them more power efficient, radiation hardened, smaller, lighter as well as more mechanically stable. Here we present the development towards a space-compatible interrogation laser system for a strontium lattice clock constructed within the Space Optical Clock (SOC2) project where we have concentrated on mechanical rigidity and size. The laser reaches a fractional frequency instability of 7.9 × 10−16 at 300 ms averaging time. The laser system uses a single extended cavity diode laser that gives enough power for interrogating the atoms, frequency comparison by a frequency comb and diagnostics. It includes fibre link stabilisation to the atomic package and to the comb. The optics module containing the laser has dimensions 60 × 45 × 8 cm3; and the ultra-stable reference cavity used for frequency stabilisation with its vacuum system takes 30 × 30 × 30 cm3. The acceleration sensitivities in three orthogonal directions of the cavity are 3.6 × 10−10/g, 5.8 × 10−10/g and 3.1 × 10−10/g, where g ≈ 9.8 m/s2 is the standard gravitational acceleration.
Protein characterization of intracellular target-sorted, formalin-fixed cell subpopulations
Authors: Sadick Jessica S. , Boutin Molly E. , Hoffman-Kim Diane , Darling Eric M.
Published: September 2016

Cellular heterogeneity is inherent in most human tissues, making the investigation of specific cell types challenging. Here, we describe a novel, fixation/intracellular target-based sorting and protein extraction method to provide accurate protein characterization for cell subpopulations. Validation and feasibility tests were conducted using homogeneous, neural cell lines and heterogeneous, rat brain cells, respectively. Intracellular proteins of interest were labeled with fluorescent antibodies for fluorescence-activated cell sorting. Reproducible protein extraction from fresh and fixed samples required lysis buffer with high concentrations of Tris-HCl and sodium dodecyl sulfate as well as exposure to high heat. No deterioration in protein amount or quality was observed for fixed, sorted samples. For the feasibility experiment, a primary rat subpopulation of neuronal cells was selected for based on high, intracellular β-III tubulin signal. These cells showed distinct protein expression differences from the unsorted population for specific (phosphorylated tau) and non-specific (total tau) protein targets. Our approach allows for determining more accurate protein profiles directly from cell types of interest and provides a platform technology in which any cell subpopulation can be biochemically investigated.
MALDI-TOF-MS reveals differential N-linked plasma- and IgG-glycosylation profiles between mothers and their newborns
Authors: Jansen Bas C. , Bondt Albert , Reiding Karli R. , Scherjon Sicco A. , Vidarsson Gestur , Wuhrer Manfred
Published: September 2016

During pregnancy, the mother provides multiple nutrients and substances to the foetus, with maternal immunoglobulin G (IgG) being actively transported to the foetus. Newborns depend on maternal IgG for immune-protection in their first months. The glycosylation of IgG has been shown to influence its dynamics, e.g. receptor binding. While minor differences in IgG glycosylation have been found between IgG derived from maternal blood and umbilical cord blood (UC) of newborn children, the differential glycosylation of maternal and UC plasma has hitherto not been studied. Here, we studied the N-glycosylation of IgG and total plasma proteome of both maternal and UC plasma of 42 pairs of mothers and newborn children. A total of 37 N-glycans were quantified for IgG and 45 for the total plasma N-glycome (TPNG). The study showed slightly higher levels of galactosylation for UC IgG than maternal IgG, confirming previous results, as well as lower bisection and sialylation. Furthermore, the TPNG results showed lower values for galactosylation and sialylation and higher values for fucosylation in the UC plasma. In conclusion, this study presents some novel insights into IgG glycosylation differences as well as the first broad overview of the differential plasma glycosylation between mothers and newborns.
Highly conductive and pure gold nanostructures grown by electron beam induced deposition
Authors: Shawrav Mostafa M. , Taus Philipp , Wanzenboeck Heinz D. , Schinnerl M. , Stöger-Pollach M. , Schwarz S. , Steiger-Thirsfeld A. , Bertagnolli Emmerich
Published: September 2016

This work introduces an additive direct-write nanofabrication technique for producing extremely conductive gold nanostructures from a commercial metalorganic precursor. Gold content of 91 atomic % (at. %) was achieved by using water as an oxidative enhancer during direct-write deposition. A model was developed based on the deposition rate and the chemical composition and it explains the surface processes that lead to the increases in gold purity and deposition yield. Co-injection of an oxidative enhancer enabled Focused Electron Beam Induced Deposition (FEBID)—a maskless, resistless deposition method for three dimensional (3D) nanostructures—to directly yield pure gold in a single process step, without post-deposition purification. Gold nanowires displayed resistivity down to 8.8 μΩ cm. This is the highest conductivity achieved so far from FEBID and it opens the possibility of applications in nanoelectronics, such as direct-write contacts to nanomaterials. The increased gold deposition yield and the ultralow carbon level will facilitate future applications such as the fabrication of 3D nanostructures in nanoplasmonics and biomolecule immobilization.
Emergence of global scaling behaviour in the coupled Earth-atmosphere interaction
Authors: Fallah Bijan , Saberi Abbas Ali , Sodoudi Sahar
Published: September 2016

Scale invariance property in the global geometry of Earth may lead to a coupled interactive behaviour between various components of the climate system. One of the most interesting correlations exists between spatial statistics of the global topography and the temperature on Earth. Here we show that the power-law behaviour observed in the Earth topography via different approaches, resembles a scaling law in the global spatial distribution of independent atmospheric parameters. We report on observation of scaling behaviour of such variables characterized by distinct universal exponents. More specifically, we find that the spatial power-law behaviour in the fluctuations of the near surface temperature over the lands on Earth, shares the same universal exponent as of the global Earth topography, indicative of the global persistent role of the static geometry of Earth to control the steady state of a dynamical atmospheric field. Such a universal feature can pave the way to the theoretical understanding of the chaotic nature of the atmosphere coupled to the Earth’s global topography.
Histone Deacetylase Inhibitor Phenylbutyrate Exaggerates Heart Failure in Pressure Overloaded Mice independently of HDAC inhibition
Authors: Ma Jing , Luo Tao , Zeng Zhi , Fu Haiying , Asano Yoshihiro , Liao Yulin , Minamino Tetsuo , Kitakaze Masafumi
Published: September 2016

4-Sodium phenylbutyrate (PBA) has been reported to inhibit endoplasmic reticulum stress and histone deacetylation (HDAC), both of which are novel therapeutic targets for cardiac hypertrophy and heart failure. However, it is unclear whether PBA can improve heart function. Here, we tested the effects of PBA and some other HDAC inhibitors on cardiac dysfunction induced by pressure overload. Transverse aortic constriction (TAC) was performed on male C57BL/6 mice. PBA treatment (100 mg/kg, 6 weeks) unexpectedly led to a higher mortality, exacerbated cardiac remodelling and dysfunction. Similar results were noted in TAC mice treated with butyrate sodium (BS), a PBA analogue. In contrast, other HDAC inhibitors, valproic acid (VAL) and trichostatin A (TSA), improved the survival. All four HDAC inhibitors induced histone H3 acetylation and inhibited HDAC total activity. An individual HDAC activity assay showed that rather than class IIa members (HDAC4 and 7), PBA and BS predominantly inhibited class I members (HDAC2 and 8), whereas VAL and TSA inhibited all of them. These findings indicate that PBA and BS accelerate cardiac hypertrophy and dysfunction, whereas VAL and TSA have opposing effects.
Paraspeckles modulate the intranuclear distribution of paraspeckle-associated Ctn RNA
Authors: Anantharaman Aparna , Jadaliha Mahdieh , Tripathi Vidisha , Nakagawa Shinichi , Hirose Tetsuro , Jantsch Michael F. , Prasanth Supriya G. , Prasanth Kannanganattu V.
Published: September 2016

Paraspeckles are sub-nuclear domains that are nucleated by long noncoding RNA Neat1. While interaction of protein components of paraspeckles and Neat1 is understood, there is limited information on the interaction of non-structural RNA components with paraspeckles. Here, by varying paraspeckle number and size, we investigate how paraspeckles influence the nuclear organization of their non-structural RNA component Ctn RNA. Our results show that Ctn RNA remains nuclear-retained in the absence of intact paraspeckles, suggesting that they do not regulate nuclear retention of Ctn RNA. In the absence of Neat1, Ctn RNA continues to interact with paraspeckle protein NonO to form residual nuclear foci. In addition, in the absence of Neat1-nucleated paraspeckles, a subset of Ctn RNA localizes to the perinucleolar regions. Concomitant with increase in number of paraspeckles, transcriptional reactivation resulted in increased number of paraspeckle-localized Ctn RNA foci. Similar to Neat1, proteasome inhibition altered the localization of Ctn RNA, where it formed enlarged paraspeckle-like foci. Super-resolution structured illumination microscopic analyses revealed that in paraspeckles, Ctn RNA partially co-localized with Neat1, and displayed a more heterogeneous intra-paraspeckle localization. Collectively, these results show that while paraspeckles do not influence nuclear retention of Ctn RNA, they modulate its intranuclear compartmentalization.
CRHunter: integrating multifaceted information to predict catalytic residues in enzymes
Authors: Sun Jun , Wang Jia , Xiong Dan , Hu Jian , Liu Rong
Published: September 2016

A variety of algorithms have been developed for catalytic residue prediction based on either feature- or template-based methodology. However, no studies have systematically compared these two strategies and further considered whether their combination could improve the prediction performance. Herein, we developed an integrative algorithm named CRHunter by simultaneously using the complementarity between feature- and template-based methodologies and that between structural and sequence information. Several novel structural features were generated by the Delaunay triangulation and Laplacian transformation of enzyme structures. Combining these features with traditional descriptors, we invented two support vector machine feature predictors based on both structural and sequence information. Furthermore, we established two template predictors using structure and profile alignments. Evaluated on datasets with different levels of homology, our feature predictors achieve relatively stable performance, whereas our template predictors yield poor results when the homological relationships become weak. Nevertheless, the hybrid algorithm CRHunter consistently achieves optimal performance among all our predictors. We also illustrate that our methodology can be applied to the predicted structures of enzymes. Compared with state-of-the-art methods, CRHunter yields comparable or better performance on various datasets. Finally, the application of this algorithm to structural genomics targets sheds light on solved protein structures with unknown functions.
Expression profiling of cutaneous squamous cell carcinoma with perineural invasion implicates the p53 pathway in the process
Authors: Warren Timothy A. , Broit Natasa , Simmons Jacinta L. , Pierce Carly J. , Chawla Sharad , Lambie Duncan L. J. , Quagliotto Gary , Brown Ian S. , Parsons Peter G. , Panizza Benedict J. , Boyle Glen M.
Published: September 2016

Squamous cell carcinoma (SCC) is the second most common cancer worldwide and accounts for approximately 30% of all keratinocyte cancers. The vast majority of cutaneous SCCs of the head and neck (cSCCHN) are readily curable with surgery and/or radiotherapy unless high-risk features are present. Perineural invasion (PNI) is recognized as one of these high-risk features. The molecular changes during clinical PNI in cSCCHN have not been previously investigated. In this study, we assessed the global gene expression differences between cSCCHN with or without incidental or clinical PNI. The results of the analysis showed signatures of gene expression representative of activation of p53 in tumors with PNI compared to tumors without, amongst other alterations. Immunohistochemical staining of p53 showed cSCCHN with clinical PNI to be more likely to exhibit a diffuse over-expression pattern, with no tumors showing normal p53 staining. DNA sequencing of cSCCHN samples with clinical PNI showed no difference in mutation number or position with samples without PNI, however a significant difference was observed in regulators of p53 degradation, stability and activity. Our results therefore suggest that cSCCHN with clinical PNI may be more likely to contain alterations in the p53 pathway, compared to cSCCHN without PNI.
Magnetic moment collapse induced axial alternative compressibility of Cr2TiAlC2 at 420 GPa from first principle
Authors: Ze-Jin Yang , Rong-Feng Linghu , Qing-He Gao , Heng-Na Xiong , Zhi-Jun Xu , Ling Tang , Guo-Zhu Jia , Yun-Dong Guo
Published: September 2016

The electronic structure and thermodynamical properties of Cr2TiAlC2 are studied by first principles under pressure. The obtained results observed that the ferromagnetic order is the most stable ground state and the magnetic moment will collapse at about 50 GPa. As a result, the lattice a axis becomes stiffer above about 420 GPa, ultimately presenting the same axial compressibility trends with those of nonmagnetic compounds Mo2TiAlC2 and hypothetical Cr2TiAlC2. The elastic constants and phonon dispersion curves demonstrate the structural stability during the disappearance of magnetic moment and occurrence of axial alternative compressibility. The density of states and energy band calculations confirmed the existence of magnetic moment of Cr2TiAlC2 at 0 GPa and disappearance at high pressures above 50 GPa. Evolutions of magnetic moment collapse with pressure are confirmed by a variety of properties. The obtained grüneisen parameter and thermal expansion coefficients show the maximum value among the known MAX phases, to date and to the author’s knowledge.
Effector Diversification Contributes to Xanthomonas oryzae pv. oryzae Phenotypic Adaptation in a Semi-Isolated Environment
Authors: Quibod Ian Lorenzo , Perez-Quintero Alvaro , Booher Nicholas J. , Dossa Gerbert S. , Grande Genelou , Szurek Boris , Vera Cruz Casiana , Bogdanove Adam J. , Oliva Ricardo
Published: September 2016

Understanding the processes that shaped contemporary pathogen populations in agricultural landscapes is quite important to define appropriate management strategies and to support crop improvement efforts. Here, we took advantage of an historical record to examine the adaptation pathway of the rice pathogen Xanthomonas oryzae pv. oryzae (Xoo) in a semi-isolated environment represented in the Philippine archipelago. By comparing genomes of key Xoo groups we showed that modern populations derived from three Asian lineages. We also showed that diversification of virulence factors occurred within each lineage, most likely driven by host adaptation, and it was essential to shape contemporary pathogen races. This finding is particularly important because it expands our understanding of pathogen adaptation to modern agriculture.
Dissipation induced by phonon elastic scattering in crystals
Authors: Li Guolong , Ren Zhongzhou , Zhang Xin
Published: September 2016

We demonstrate that the phonon elastic scattering leads to a dominant dissipation in crystals at low temperature. The two-level systems (TLSs) should be responsible for the elastic scattering, whereas the dissipation induced by static-point defects (SPDs) can not be neglected. One purpose of this work is to show how the energy splitting distribution of the TLS ensemble affects the dissipation. Besides, this article displays the proportion of phonon-TLS elastic scattering to total phonon dissipation. The coupling coefficient "Equation missing" of phonon-SPD scattering and the constant P0 of the TLS distribution are important that we estimate their magnitudes in this paper. Our results is useful to understand the phonon dissipation mechanism and give some clues to improve the performance of mechanical resonators, apply the desired defects, or reveal the atom configuration in lattice structure of disordered crystals.
Involvement of Endoplasmic Reticulum Stress, Autophagy and Apoptosis in Advanced Glycation End Products-Induced Glomerular Mesangial Cell Injury
Authors: Chiang Chih-Kang , Wang Ching-Chia , Lu Tien-Fong , Huang Kuo-How , Sheu Meei-Ling , Liu Shing-Hwa , Hung Kuan-Yu
Published: September 2016

Advanced glycation end-products (AGEs)-induced mesangial cell death is one of major causes of glomerulus dysfunction in diabetic nephropathy. Both endoplasmic reticulum (ER) stress and autophagy are adaptive responses in cells under environmental stress and participate in the renal diseases. The role of ER stress and autophagy in AGEs-induced mesangial cell death is still unclear. Here, we investigated the effect and mechanism of AGEs on glomerular mesangial cells. AGEs dose-dependently decreased mesangial cell viability and induced cell apoptosis. AGEs also induced ER stress signals in a time- and dose-dependent manner. Inhibition of ER stress with 4-phenylbutyric acid effectively inhibited the activation of eIF2α and CHOP signals and reversed AGEs-induced cell apoptosis. AGEs also activated LC-3 cleavage, increased Atg5 expression and decreased p62 expression, which indicated the autophagy induction in mesangial cells. Inhibition of autophagy by Atg5 siRNAs transfection aggravated AGEs-induced mesangial cell apoptosis. Moreover, ER stress inhibition by 4-phenylbutyric acid significantly reversed AGEs-induced autophagy, but autophagy inhibition did not influence the AGEs-induced ER stress-related signals activation. These results suggest that AGEs induce mesangial cell apoptosis via an ER stress-triggered signaling pathway. Atg5-dependent autophagy plays a protective role. These findings may offer a new strategy against AGEs toxicity in the kidney.
Grassy Silica Nanoribbons and Strong Blue Luminescence
Authors: Wang Shengping , Xie Shuang , Huang Guowei , Guo Hongxuan , Cho Yujin , Chen Jun , Fujita Daisuke , Xu Mingsheng
Published: September 2016

Silicon dioxide (SiO2) is one of the key materials in many modern technological applications such as in metal oxide semiconductor transistors, photovoltaic solar cells, pollution removal, and biomedicine. We report the accidental discovery of free-standing grassy silica nanoribbons directly grown on SiO2/Si platform which is commonly used for field-effect transistors fabrication without other precursor. We investigate the formation mechanism of this novel silica nanostructure that has not been previously documented. The silica nanoribbons are flexible and can be manipulated by electron-beam. The silica nanoribbons exhibit strong blue emission at about 467 nm, together with UV and red emissions as investigated by cathodoluminescence technique. The origins of the luminescence are attributed to various defects in the silica nanoribbons; and the intensity change of the blue emission and green emission at about 550 nm is discussed in the frame of the defect density. Our study may lead to rational design of the new silica-based materials for a wide range of applications.
Destabilization of the IFT-B cilia core complex due to mutations in IFT81 causes a Spectrum of Short-Rib Polydactyly Syndrome
Authors: Duran Ivan , Taylor S. Paige , Zhang Wenjuan , Martin Jorge , Forlenza Kimberly N. , Spiro Rhonda P. , Nickerson Deborah A. , Bamshad Michael , Cohn Daniel H. , Krakow Deborah
Published: September 2016

Short-rib polydactyly syndromes (SRPS) and Asphyxiating thoracic dystrophy (ATD) or Jeune Syndrome are recessively inherited skeletal ciliopathies characterized by profound skeletal abnormalities and are frequently associated with polydactyly and multiorgan system involvement. SRPS are produced by mutations in genes that participate in the formation and function of primary cilia and usually result from disruption of retrograde intraflagellar (IFT) transport of the cilium. Herein we describe a new spectrum of SRPS caused by mutations in the gene IFT81, a key component of the IFT-B complex essential for anterograde transport. In mutant chondrocytes, the mutations led to low levels of IFT81 and mutant cells produced elongated cilia, had altered hedgehog signaling, had increased post-translation modification of tubulin, and showed evidence of destabilization of additional anterograde transport complex components. These findings demonstrate the importance of IFT81 in the skeleton, its role in the anterograde transport complex, and expand the number of loci associated with SRPS.
Orientational binding modes of reporters in a viral-nanoparticle lateral flow assay
Authors: Kim Jinsu , Poling-Skutvik Ryan , Trabuco João R. C. , Kourentzi Katerina , Willson Richard C. , Conrad Jacinta C.
Published: September 2016

Capture of ellipsoidal viral-nanoparticle reporters in a model lateral flow assay is enhanced by behavior of the anisotropic reporters in the local flow field.
Strategies for large-scale targeted metabolomics quantification by liquid chromatography-mass spectrometry
Authors: Zhou Juntuo , Yin Yuxin
Published: September 2016

Advances in liquid chromatography-mass spectrometry (LC-MS) instruments and analytical strategies have brought about great progress in targeted metabolomics analysis.
CompVis: a novel method for drinking water alkalinity and total hardness analyses
Authors: Damasceno Deangelis , Toledo Thiago Gomes , da Silva Soares Anderson , Botelho de Oliveira Sérgio , Elcana de Oliveira Anselmo
Published: September 2016

A new green analytical chemistry method using a computer vision approach is proposed to measure alkalinity, Ca2+ and Mg2+ hardness, and total hardness of drinking water samples.
The construction and application of chiral electrochemical sensors
Authors: Li Zhenliang , Mo Zunli , Meng Shujuan , Gao Huhu , Niu Xiaohui , Guo Ruibin
Published: September 2016

The review is based on the construction and application of chiral electrochemical sensors in the last three years and presents recent advances in applications of chiral electrochemical sensors based on a three-point interaction and the methods for fabricating chiral surfaces for enantioselective recognition.
Near infrared imaging-guided photodynamic therapy under an extremely low energy of light by galactose targeted amphiphilic polypeptide micelle encapsulating BODIPY-Br2
Authors: Liu Le , Ruan Zheng , Li Tuanwei , Yuan Pan , Yan Lifeng
Published: September 2016

Galactose targeted polymeric micelle encapsulating BODIPY-Br2 has been prepared which showed NIR imaging-guided photodynamic therapy under an extremely low energy of light.
Modelling the chemistry of Mn-doped MgO for bulk and (100) surfaces
Authors: Logsdail Andrew J. , Downing Christopher A. , Keal Thomas W. , Sherwood Paul , Sokol Alexey A. , Catlow C. Richard A.
Published: September 2016

We have investigated the energetic properties of Mn-doped MgO bulk and (100) surfaces using a QM/MM embedding computational method, calculating the formation energy for doped systems, as well as for surface defects, and the subsequent effect on chemical reactivity.
DFT insights into the adsorption of NH3-SCR related small gases in Mn-MOF-74
Authors: Zhang Minhua , Huang Xuewei , Chen Yifei
Published: September 2016

The adsorption properties of six NH3-SCR related small gases and the competitive adsorption of NH3, SO2 and NH3, H2O were investigated.
Giant reduction of thermal conductivity in a two-dimensional nitrogenated holey C2N nanosheet
Authors: Zhang Tingting , Zhu Liyan
Published: September 2016

Giant suppression of thermal conductivity of C2N due to its nitrogenated holey structure.
Overcoming the Achilles' heel of photodynamic therapy
Authors: Fan Wenpei , Huang Peng , Chen Xiaoyuan
Published: September 2016

This review summarizes the latest progress in deep photodynamic therapy (PDT), which overcomes the Achilles' heel of PDT.
Pt@SnOx/SiO2 catalysts with enhanced selectivity to allyl alcohol for acrolein hydrogenation
Authors: Lan Xiaocheng , Wang Tiefeng , Li Xiaodan , Huang Ning , Wang Jinfu
Published: September 2016

A core–shell structure of Pt@SnOx/SiO2 catalyst was developed for the hydrogenation of acrolein with high activity and selectivity to allyl alcohol.
Calcium l-tartrate complex formation in neutral and in hyperalkaline aqueous solutions
Authors: Gácsi Attila , Kutus Bence , Csendes Zita , Faragó Tünde , Peintler Gábor , Pálinkó István , Sipos Pál
Published: September 2016

In hyper-alkaline aqueous solutions, Ca2+ and l-tartrate (Tar2−) ions form CaTarH−1−(aq) and CaTarH−22−(aq) complexes containing deprotonated alcoholate group(s).
From lignin association to nano-/micro-particle preparation: extracting higher value of lignin
Authors: Zhao Wenwen , Simmons Blake , Singh Seema , Ragauskas Arthur , Cheng Gang
Published: September 2016

As the most abundant source of renewable aromatic compounds on the planet, lignin is gaining growing interest in replacing petroleum-based chemicals and products. Lignin nanoparticles offer many opportunities for value-added applications of lignin.
Double-cocatalysts promote charge separation efficiency in CO2 photoreduction: spatial location matters
Authors: Dong Chunyang , Xing Mingyang , Zhang Jinlong
Published: September 2016

Pt/HCTSO with a double-cocatalyst spatially separated structure displays an enhanced performance in the photocatalytic reduction of CO2 for the selective generation of CH4.
Self-assembly, structural order and mechanism of γ-Fe2O3@SiO2 ellipsoids induced by magnetic fields
Authors: Zhang Xin , Niu Yongan , Zhao Jiupeng , Li Yao
Published: September 2016

Ordered ellipsoid templates are successfully fabricated in the air–liquid interface and induced by magnetic field. The influence factors on ordered structures are investigated and evaluated by SEM and reflective spectra. The optimal conditions are determined by different self-assembly processes and optical analyses.
Selectivity and activity in catalytic hydrogenation of azido groups over Pd nanoparticles on aluminum oxy-hydroxide
Authors: Kara Belgüzar Yasemin , Kılbaş Benan , Göksu Haydar
Published: September 2016

A practical and effective catalytic method has been developed for the reduction of aryl azides in the presence of PdAlO(OH) nanoparticles and sodium borohydride.
Studies on the radical polymerization of monomeric ionic liquids: nanostructure ordering as a key factor controlling the reaction and properties of nascent polymers
Authors: Tarnacka Magdalena , Chrobok Anna , Matuszek Karolina , Neugebauer Dorota , Bielas Rafał , Golba Sylwia , Wolnica Kamila , Dulski Mateusz , Kaminski Kamil , Paluch Marian
Published: September 2016

A linear relationship between the α evaluated from DSC, FTIR and dc conductivity (from BDS) was found.
Visible-light-induced water reduction reaction for efficient hydrogen production by N-doped In2Ga2ZnO7 nanoparticle decorated on RGO sheets
Authors: Padhi Deepak kumar , Parida Kulamani , Singh S. K.
Published: September 2016

Efficient hydrogen production over graphene-based N-doped In2Ga2ZnO7 nanocomposite under visible irradiation.
Hydrophobic associated polymer “grafted onto” nanosilica as a multi-functional fluid loss agent for oil well cement under ultrahigh temperature
Authors: Xia Xiujian , Guo Jintang , Feng Yakai , Chen Di , Yu Yongjin , Jin Jianzhou , Liu Shuoqiong
Published: September 2016

In this study, a novel hydrophobic associated polymer/nanosilica composite with a micro-crosslinking structure was synthesized to address the drawbacks of traditional polymers in ultrahigh temperature performance.
Determination of ultra-trace amounts of chlorophenols in rain, tap and river water by an electrochemically controlled in-tube solid phase microextraction method
Authors: Asiabi Hamid , Yamini Yadollah , Shamsayei Maryam
Published: September 2016

A nanostructured copolymer coating consisting of PPy doped with Naf was electrochemically synthesized on the inner surface of a stainless steel capillary tube. It was utilized to extract trace pollutants from water samples.
Stereoselective oxidation of alkanes with m-CPBA as an oxidant and cobalt complex with isoindole-based ligands as catalysts
Authors: Nesterova Oksana V. , Kopylovich Maximilian N. , Nesterov Dmytro S.
Published: September 2016

Coordination compound of cobalt catalyses hydroxylation of inert C–H bonds with 98% retention of stereoconfiguration of alkane skeleton.
Synthesis and biological evaluation of new pyranopyridine derivatives catalyzed by guanidinium chloride-functionalized γ-Fe2O3/HAp magnetic nanoparticles
Authors: Azarifar Davood , Ghaemi Masoumeh , Golbaghi Maryam , Karamian Roya , Asadbegy Mostafa
Published: September 2016

Herein, we described the synthesis of γ-Fe2O3@HAP-GndCl MNPs as an efficient and recyclable nanocatalyst for synthesis of new pyranopyridine derivatives under solvent-free condition and then evaluated for theirs antioxidant and antifungal activities.
Characterization and mechanism analysis of AgBr mixed cuboid WO3 rods with enhanced photocatalytic activity
Authors: Yao Shanshan , Xue Sikang , Zhang Junhao , Shen Xiangqian
Published: September 2016

The possible mechanisms for the formation of photocatalysts, enhanced photocatalytic properties and deactivation of the AgBr/m-WO3 were investigated, respectively.
Monodomain hydrogels prepared by shear-induced orientation and subsequent gelation
Authors: Lin Xiao Ying , Wang Zhi Jian , Pan Pengju , Wu Zi Liang , Zheng Qiang
Published: September 2016

Shear-induced orientation of liquid crystalline hydroxypropylcellulose solution with reactants is frozen by subsequent polymerization and gelation process, resulting in monodomain hydrogel with anisotropic optical, swelling, and mechanical properties.
Carbide decorated carbon nanotube electrocatalyst for high-efficiency hydrogen evolution from seawater
Authors: Zhao Yuanyuan , Tang Qunwei , He Benlin , Yang Peizhi
Published: September 2016

Co3Mo3C/CNT electrocatalysts are developed for high-efficiency hydrogen evolution by seawater splitting.
Synthesis and characterization of functionalized titania-supported Pd catalyst deriving from new orthopalladated complex of benzophenone imine: catalytic activity in the copper-free Sonogashira cross-coupling reactions at low palladium loadings
Authors: Karami Kazem , Abedanzadeh Sedigheh , Hervés Pablo
Published: September 2016

Efficient catalytic activity of TiO2-supported Pd catalyst in the copper, amine and phosphine free Sonogashira cross-coupling reactions at low Pd-loadings.
Bimagnetic urchin-like Co3O4/CoFe2O4 nanocomposites: synthesis and magnetic properties
Authors: Fan Shan , Wang Wen , Ke Hua , Rao Jian-Cun , Zhou Yu
Published: September 2016

The nanocomposite Co3O4/CoFe2O4 heterostructured material was produced via a simple solid–solid reaction of an iron precursor with urchin-like Co3O4. The nanocomposite behaves as an exchange coupled system with a cooperative magnetic switching.
Treatment of wastewater derived from dinitrodiazophenol (DDNP) manufacturing by the Fe/Cu/O3 process
Authors: Cao Jinyan , Xiong Zhaokun , Yuan Yue , Lai Bo , Yang Ping
Published: September 2016

In this paper, the Fe/Cu bimetallic particles and ozone were combined to decompose or transform the toxic and refractory pollutants in dinitrodiazophenol (DDNP) wastewater.
Preparation of polyaniline/graphene composites with excellent anti-corrosion properties and their application in waterborne polyurethane anticorrosive coatings
Authors: Cai Kewen , Zuo Shixiang , Luo Shipin , Yao Chao , Liu Wenjie , Ma Jianfeng , Mao Huihui , Li Zhongyu
Published: September 2016

Polyaniline, a novel conductive polymer, has been widely used as an anti-corrosive filler.
Visible light responsive Fe–ZnS/nickel foam photocatalyst with enhanced photocatalytic activity and stability
Authors: Xue Yanei , Su Rongjun , Zhang Guangshan , Wang Qiao , Wang Peng , Zhang Wen , Wang Zhihong
Published: September 2016

ZnFeS photocatalysts were successfully decorated on nickel foam to form a ZnFeS/nickel foam composite photocatalyst.
All-cellulose composites with ultra-high mechanical properties prepared through using straw cellulose fiber
Authors: Wei Xiao , Wei Wei , Cui Yu-hu , Lu Ting-ju , Jiang Man , Zhou Zuo-wan , Wang Yong
Published: September 2016

With incorporating the activated SCF which exhibits excellent interfacial interaction with matrix, ultra-high mechanical properties are achieved for the ACCs.
Nitrogen-doped mesoporous hollow carbon nanoflowers as high performance anode materials of lithium ion batteries
Authors: Qian Chen , Guo Ping , Zhang Xiue , Zhao Rongfang , Wu Qianhui , Huan Long , Shen Xiao , Chen Ming
Published: September 2016

Nitrogen-doped mesoporous hollow carbon nanoflowers (N-HCNF) are successfully prepared by a facile hard-template route via a hydrothermal process, subsequent carbonization and etching.
Activation of radical addition to graphene by chemical hydrogenation
Authors: Whitener Keith E. , Lee Woo-Kyung , Stine Rory , Tamanaha Cy R. , Kidwell David A. , Robinson Jeremy T. , Sheehan Paul E.
Published: September 2016

Hydrogenated graphene undergoes elimination and substitution reactions in the presence of radical initiators.
Nanosized spinel Cu–Mn mixed oxide catalyst prepared via solvent evaporation for liquid phase oxidation of vanillyl alcohol using air and H2O2
Authors: Saha Subrata , Abd Hamid Sharifah Bee
Published: September 2016

Spinel Cu–Mn mixed oxide preparedviasolvent evaporation method demonstrating superior catalytic activity.
A new water-soluble heteronuclear PdII–AuI pincer complex as two-photon luminescent probe for biological Co2+ detection
Authors: Tabrizi Leila , Chiniforoshan Hossein
Published: September 2016

A new water-soluble heteronuclear PdII–AuI pincer complex was synthesized and investigated for biological Co2+ detection.
Identification of a novel selective inhibitor of mutant isocitrate dehydrogenase 1 at allosteric site by docking-based virtual screening
Authors: Zou Fangxia , Pusch Stefan , Eisel Jessica , Ma Tianfang , Zhu Qihua , Deng Dawei , Gu Yueqing , Xu Yungen , von Deimling Andreas , Zha Xiaoming
Published: September 2016

Optimal docking was employed to screen SPECS compound library, followed by cellular assays of mutant and wild type of IDH1.
Molecularly imprinted polymers on multi-walled carbon nanotubes as an efficient absorbent for preconcentration of morphine and its chemiluminometric determination
Authors: Lotfi Ali , Karimi Sepideh , Hassanzadeh Javad
Published: September 2016

A simple and selective method was described for the determination of morphine based on its preconcentration by molecularly imprinted polymers on multi-walled carbon nanotubes prior to its chemiluminometric recognition.
Strong modification of intrinsic spin Hall effect in FeMn with antiferromagnetic order formation
Authors: Kang Y. , Chang Y. S. , He W. , Cai J. W. , Kang S. S.
Published: September 2016

FeMn films with and without a Cu seed layer were deposited on Y3Fe5O12 (YIG) substrates, and their inverse spin Hall effect (ISHE) was examined through both spin Seebeck effect and spin pumping.
Identification of a novel human DNA ligase I inhibitor that promotes cellular apoptosis in DLD-1 cells: an in silico and in vitro mechanistic study
Authors: Singh Deependra Kumar , Hussain Mohd. Kamil , Krishna Shagun , Deshmukh Amit Laxmikant , Shameem Mohammad , Maurya Pooja , Hajela Kanchan , Siddiqi Mohammad Imran , Banerjee Dibyendu
Published: September 2016

The compound S-097/98 is a specific inhibitor of hLig1. As shown in the figure, the compound inhibits only hLig1 while other human and non-human DNA ligases are not inhibited.
Hydrogen-adduction to open-shell graphene fragments: spectroscopy, thermochemistry and astrochemistry
Authors: O'Connor Gerard D. , Chan Bun , Sanelli Julian A. , Cergol Katie M. , Dryza Viktoras , Payne Richard J. , Bieske Evan J. , Radom Leo , Schmidt Timothy W.
Published: September 2016

H-Adducted graphene fragments are interrogated with lasers, revealing excited state bond dissociation energies and ionization energies.
Anion conducting multiblock copolymer membranes with partial fluorination and long head-group tethers
Authors: Liu Lisha , Ahlfield John , Tricker Andrew , Chu Deryn , Kohl Paul A.
Published: September 2016

Multiblock copolymer with long head-group tethers were synthesized as anion exchange membranes with high ionic conductivity and good alkaline stability.
Response to di-functionalized hyaluronic acid with orthogonal chemistry grafting at independent modification sites in rodent models of neural differentiation and spinal cord injury
Authors: Lim Hyun Ju , Perera T. Hiran , Wilems Thomas S. , Ghosh Sukhen , Zheng Yi-Yan , Azhdarinia Ali , Cao Qilin , Smith Callahan Laura A.
Published: September 2016

Hyaluronic acid functionalized with two orthogonal chemistries at different targets expedites neural maturation in vitro, while reducing inflammation in vivo.
An ultrasensitive and reversible fluorescence sensor of humidity using perovskite CH3NH3PbBr3
Authors: Xu Wei , Li Feiming , Cai Zhixiong , Wang Yiru , Luo Feng , Chen Xi
Published: September 2016

An organic–inorganic hybrid fluorescent perovskite, CH3NH3PbBr3, was synthesized by a grinding method, and applied for humidity sensing.
Global minimum of two-dimensional FeB6and an oxidization induced negative Poisson's ratio: a new stable allotrope
Authors: Li Jiao , Wei Yanpei , Fan Xinyu , Wang Hongbo , Song Yang , Chen Gang , Liang Yunye , Wang Vei , Kawazoe Yoshiyuki
Published: September 2016

A tri-FeB6sheet with a sandwich-like structure has been found to be a novel stable two-dimensional allotrope which has remarkable mechanical properties and tunable electronic properties.
Sliding mode control of robotic arms with deadzone
Authors: de Jesús Rubio José
Published: September 2016

In this study, a sliding mode controller is designed for the regulation of robotic arms with unknown behaviours in the deadzone and gravity. The sliding mode strategy is employed to compensate the unknown behaviours. Furthermore, the asymptotic stability of the controller is guaranteed by the Lyapunov technique. The application in two robotic arms shows the effectiveness of the proposed technique.
Iterative algorithms for solving continuous stochastic Lyapunov equations
Authors: Wu Ai‐Guo , Wang Xiaomei , Sreeram Victor
Published: September 2016

In this study, a novel iterative algorithm is proposed for solving coupled Lyapunov equations appearing in continuous‐time Itô stochastic systems with Markovian jump parameters. In this algorithm, some tunable parameters are introduced, and thus a combination of the information in both the last step and the current step can be utilised to update the estimation of the unknown matrix variables. The monotonicity and boundedness of the proposed algorithm are analysed, and the convergence condition for this algorithm is also given. Due to the use of the latest updated information, the proposed algorithm can achieve better convergence performance than the existing iterative algorithm by appropriately choosing the tuning parameters. An illustrative example is employed to show the effectiveness of the proposed algorithm.
Generating image descriptions with multidirectional 2D long short‐term memory
Authors: Li Shuohao , Zhang Jun , Guo Qiang , Lei Jun , Tu Dan
Published: September 2016

Connecting visual imagery with descriptive language is a challenge for computer vision and machine translation. To approach this problem, the authors propose a novel end‐to‐end model to generate descriptions for images. Some early works used convolutional neural network‐long‐short‐term memory (CNN‐LSTM) model to describe the image, where a CNN encodes the input image into feature vector and an LSTM decodes the feature vector into a description. Since two‐dimensional LSTM (2DLSTM) has property of translation invariance and can encode the relationships between regions in an image, they not only apply a CNN to extract global features of an image, but also use a multidirectional 2DLSTM to encode the feature maps extracted by CNN into structural local features. Their model is trained through maximising the likelihood of the target description sentence from the training dataset. Experiments on two challenging datasets show the accuracy of the model and the fluency of the language which is learned by their model. They compare bilingual evaluation understudy score and retrieval metric of their results with current state‐of‐the‐art scores and show the improvements on Flickr30k and MS COCO.
Design and field programmable gate array implementation of cascade neural network based flux estimator for speed estimation in induction motor drives
Authors: Venkadesan Arunachalam , Himavathi Srinivasan , Sedhuraman Karthikeyan , Muthuramalingam A.
Published: September 2016

This study presents design and hardware implementation of cascade neural network (NN) based flux estimator using field programmable gate array (FPGA) for speed estimation in induction motor drives. The main focus of this study is the FPGA implementation of cascade NN based flux estimator. The major issues in FPGA implementation are optimisation of cost (resource) and execution time. A simple non‐linear activation function called as Elliott function is used to reduce the execution time. To reduce the cost, and effectively utilise resource, the concept of layer multiplexing is adopted. The lowest bit precision needed for good performance of the estimator is identified and implemented. The proposed NN based flux estimator using simple excitation function and minimum bit precision is implemented using layer multiplexing technique. The designed estimator is tested on Spartan FPGA kit (3sd1800afg676‐4) and the results obtained are presented.
Method to design optimal communication architectures in advanced metering infrastructures
Authors: Armendariz Mikel , Johansson Christian , Nordström Lars , Yunta Huete Angel , García Lobo Miguel
Published: September 2016

This study proposes a method to determine the optimal communication architecture in advance metering infrastructures (AMI). The method starts by indicating suitable groups of meters that share similar characteristics such as distance to the secondary substation and mutual proximity. Then it connects each group of meters to the AMI‐head end through a communication architecture formed by wireless and power line communication technologies. The optimality criterion takes into account the capital expenditures, operational expenditures and the quality of service in the communication architecture. The method is tested on a low voltage (LV) network based on real utility data provided by EU FP7 DISCERN project partners. These tests show that the method is consistent with planning foresight and can be useful to assist in the AMI communication architecture designing process.
Development of a new fault zone identification scheme for busbar using logistic regression classifier
Authors: Jena Soumitri , Bhalja Bhavesh R.
Published: September 2016

This study presents the development of a new fault zone identification scheme for busbar using logistic regression binary classifier by utilising one cycle post‐fault current signals of all the bays connected to the busbar. Practicability of the presented scheme has been verified by modelling an existing 400 kV Indian power generating station in power systems computer‐aided design/electro‐magnetic transient design and control software package. The presented scheme has been tested on enormous cases (38,400) which were generated by varying system and fault parameters. The proposed scheme provides effective discrimination between internal and external faults with a very high (99.69%) overall accuracy. Moreover, it remains stable in case of heavy through fault conditions particularly with current transformer saturation during which the conventional differential protection scheme mal‐operates. Furthermore, it provides equally compatible accuracy for unknown system/unseen data set as well as for double/one‐and‐half breaker busbar arrangement. In addition, performance of the proposed scheme has been verified on the laboratory prototype and results are found to be satisfactory. The average tripping time is of the order of 23 ms in case of internal faults. At last, comparative evaluation of the proposed scheme with recently presented schemes in the literature indicates its superiority.