bluuebunny/crossref_metadata_2025 huggingface dataset:
LARGE PAROTID SWELLING WITH SQUAMOUS METAPLASIA MIMICKING SCC
Authors: Abhishek Rajul , Pandey Ashish Kumar , Usmani Kaleem , Kumar Rahul
Published: February 2024

Here we describes 28 year old multiparous female who came to department of surgical oncology with complaints of swelling over right side neck
for 8 year. This patient initially was treated by Herb Medicine/Ayurvedic Drug/Paint over swelling. Now patient came to our side as multiple
bleeding ulcers over swelling. After evaluation patient was diagnosed as chronic inammatory lesion with squamous dysplasia. Hence patient was
managed operatively by total parotidectomy. But histopathological examination of resected specimen was suggestive of Pleomorphic Adenoma
with squamous metaplasia. Here we present case report of rare histopathology variant of pleomorphic adenoma with squamous metaplasia. Very
few cases has been reported of such scenario.
COMPARATIVE STUDYOF THIOPENTONE SODIUM VERSUS PROPOFOL FOR ANAESTHETIC EFFICACY & EFFECT ON SEIZURE DURATION IN ELECTROCONVULSIVE THERAPY
Authors: Parsana Akanksha Monil , Kumar Mukesh , Verma Ajay Kumar
Published: February 2024

Introduction: Electroconvulsive treatment is a treatment where seizures are electrically induced in patients of psychiatric disorder for therapeutic
impact. Electric current in ECT can cause severe haemodynamic disturbances. Administration of anaesthetic agents can cause attenuation of
physilogical disturbances. To study impact of Thiopentone Sodium and Propofol on haemodynamics and Aims & Objectives: seizure duration
when used as anesthetic agents for ETC. After ethical clearance and wri Materials & Methods: tten informed consent of patient and surrogates the
study was conducted on 60 patients aged 20-50 yrs with no comrbidities other than the psychiatric disorder under treatment. In our Conclusion:
study we concluded that Propofol was better than Thiopentone Sodium for anaesthesia durig ECT due to more haemodynamic stability and faster
recovery at the cost of lower seizure duration. Thiopentone on the other hand provided longer seizure duration rendering it more effective
therapeutically but with more haemodynamic uctuations despite its intrinsic antiepileptic property.
Monitoring flood using Amazon SageMaker geospatial capabilities
Authors: Dua Ishneet Kaur , Patel Parth
Published: February 2024

Flood monitoring with satellite images is an effective method of
detecting and tracking floods. This approach involves the use of
satellite imagery to detect changes in water levels and identify flooded
areas. To monitor floods using satellite images, the images are analyzed
to detect changes in water levels over time. To detect changes in water
levels and identify flooded areas based on a set of predefined criteria,
we can train algorithms. Amazon SageMaker geospatial capabilities make
it easier for data scientists and machine learning (ML) engineers to
build, train, and deploy ML models using geospatial data.  These
capabilities also provide pre-trained models. One of the pre-trained
models is land cover segmentation model. This land cover segmentation
model can be run with a simple API call and can be leverage to analyze
changes in the water level.
Trajectory-Unaware Path Loss Forecast in a Distributed Massive MIMO System based on a Multivariate BiLSTM Model
Authors: Alonso Rodney Martinez , Beerten Robbert , Colpaert Achiel , Guevara Andrea P , Pollin Sofie
Published: February 2024

Cell-free massive MIMO networks have recently emerged as an attractive solution capable of solving the performance degradation at the cell edge of cellular networks. For scalability reasons, usercentric clusters were recently proposed to serve users via a subset of APs. In the case of dynamic mobile scenarios, this form of network organization requires predictive algorithms for forecasting propagation parameters to maintain performance by proactively allocating new APs to a user. In this paper, we present a BiLSTM-based multivariate path loss forecasting algorithm. Thanks to the combination of dual prediction by the BiLSTM and diversity from multiple antennas, our model mitigates the error propagation typically faced by sequential neural networks for time-series forecasting. In the evaluated scenario, from 2 to 10 steps ahead, we reduce the propagation of the error by a factor of 18 compared to previous research on path loss forecasting by an LSTM time-series-based model. In contrast to parallel transformer solutions, the complexity cost of our algorithm is also significantly lower.
Direitos Autorais e Inteligência Artificial
Authors: Valente Catherine Juglair Nogari , Sartori Rejane
Published: February 2024

The aim of the research is to map and analyze the scientific production concerning Copyright and Artificial Intelligence, aiming to comprehend how research in this field is evolving across different regions of the world. This research is designed as descriptive-exploratory with a quantitative approach. The employed method was the Knowledge Development Process-constructivist. Using a systematic approach, 40 articles published between 2017 and 2022 were examined, collected from the Scopus and Web of Science databases. The data were analyzed in the context of bibliometric laws. The findings suggest an increasing trend in publications on Copyright and Artificial Intelligence in recent years, indicating an upward curve in scientific production. The most addressed themes, significant authors, and notable institutions in this context were identified. Furthermore, the distribution of authors concerning their productivity, relevance, and impact was detailed. This bibliometric analysis contributes to understanding the intersection between Copyright and Artificial Intelligence, providing a detailed view of scientific production dynamics and identifying trends for future research in this field.
أثر المقدرات الاستراتيجية في الاستباقية التنظيمية في عينة من شركات السياحية في النجف الأشرف
Authors: العنزي قاسم , رزاق حسن
Published: February 2024

يهدف البحث الى التعرف على المقدرات الاستراتيجية وأثرها في الاستباقية التنظيمية في شركات السياحية في محافظة النجف الاشرف وتشخيص مستوى وجود العلاقة بين المتغيرين من خلال قياس ابعادهما وتحديد طبيعية العلاقات بينهما ولتحقيق هذه الاهداف, فقد تم اعتماد المنهج (الوصفي- التحليلي) ، واستخدمت الاستبانة كأداة للقياس، وكان مجتمع البحث هو العاملين في قطاع السياحية في محافظة النجف الاشرف والبالغ عددهم 103 فرد , وتم توزيع 110 استمارة استبيان بطريقة العينة العشوائية وكانت نسبة الاسترجاع هو ( 93,6,%) وكان عدد الاستبانات الصالحة (103) استبانة أي بنسبة تمثيل للعينة ( 100%) ، استخدم الباحث البرامج الاحصائية المتقدمة (SPSS v.26) لغرض تحليل البيانات واختبار الفرضيات الرئيسة والفرعية المنبثقة منها الدراسة, وكانت فترة البحث من 15/11/2020 الى 15/11/,2021 ودراسة طبيعية العلاقة المتداخلة بين متغيرات البحث في الشركات السياحية وتحليلها والاستفادة من نتائج هذه العلاقة.
إشكالية العلاقة والصلاحيات السياسية بين المركز وإقليم كردستان
Authors: العنبر إياد , خزعل حنين
Published: February 2024

تعد الغاية والهدف من الأخذ بالنظام الفدرالي كمحاولة لمنع تركيز السلطة بيد واحدة وتعزيز الحكم المحلي, لكن غموض النصوص الدستورية في النموذج العراقي ادى إلى تداخل في الاختصاصات بين الحكومة الاتحادية والاقاليم والمحافظات غير المنتظمة في اقليم وتنظيم شكل العلاقة بينهم, فضلاً عن غموض النصوص الدستورية فإن عدم تطبيق نهج فلسفة النظام الفدرالي وعدم مراعاتها للخصوصية المجتمعية التي يتمتع بها المجتمع العراقي مما اثر على إدارة الدولة وخلق الكثير من المشاكل التي لا حصر لها ما بين الحكومة الاتحادية واقليم كردستان.

وباتت العلاقة بين الحكومة الاتحادية واقليم كردستان يسودها التوتر الدائم بسبب نقاط خلاف عديدة نتيجة الصلاحيات الكثيرة التي يتمتع بها اقليم كردستان, مما اثر على اداء النظام السياسي بأكمله وبالتالي انعكاسه على المجتمع وكافة مؤسسات الدولة وعدم قدرة الدولة على فرض سلطة القانون نتيجة عوامل عديدة، وسيتم التطرق في البحث الى عدد من هذه الاشكاليات.
تقنيات الاعمال الالكترونية وتأثيرها على جودة الخدمة في المؤسسات الصحية
Authors: الميالي حاكم , شنين يحيى
Published: February 2024

تهدف الدراسة الى إظهار أثر تطبيق تقنيات الأعمال الإلكترونية كمتغير مستقل بإبعادها (البنى التحتية الإلكترونية ,تطبيق نظم الأعمال الإلكترونية للمستشفى ,نظم المعلومات الصحية), في جودة الخدمة كمتغير معتمد من خلال أبعادها  (المعولية ، الوقت ، الاستجابة ، التأكيد), وبالنظر لأهمية الموضوع في القطاع الصحي  وتأثيره في حياة معظم الناس , لذلك  أجري البحث في 3)) مستشفيات حكومية  في محافظة النجف الاشرف إذ تم استطلاع آراء عينة مكونة من (200) من الأفراد العاملين في المؤسسات الصحية, وتم ذلك عن طريق الاستبانة كأداة رئيسة  في الحصول على البيانات والمعلومات وأيضاً المقابلات الشخصية وكذلك المصادر والمراجع العربية والأجنبية أما الأساليب الإحصائية المستخدمة في الدراسة هي (البرنامج الإحصائي (SPSS.V.20 , (Amos.v.20مثل التوزيع الطبيعي, التحليل العاملي ,نمذجة المعادلة الهيكلية ,اختبار فرضيات الفروق لاستخراج النتائج.
الإنسان في المعرفة القرآنية
Authors: الحجار عدي , غنتاب فاضل
Published: February 2024

القرآن الكريم خطاب هداية ورشاد للإنسان وهو المعجزة الباقية وتكفل في منظومته المعرفية ببناء الإنسان في كل حال وزمان ومكان، ففيه اصول للآداب والأخلاق والعلوم في مختلف مجالات الحياة والاجتماع, ورسم له الطريق الذي يؤدي به إلى الفلاح في الدنيا والآخرة إن سلكه وسار على هداه, فهو ذكر الهدف وأوضح السبل الكفيلة للوصول إلى هذا الهدف "وهذا السير الذي يحتوي على المعاناة باستمرار يفترض طريقاً لا محالة، فإن السير نحو هدف يفترض حتماً طريقاً ممتداً بين السائر وبين ذلك الهدف، وهذا الطريق هو الذي تحدثت عنه الآيات الكريمة في المواضع المتفرقة من الكتاب العزيز تحت اسم سبيل الله واسم الصراط واسم صراط الله. وقسم البحث على مطلبين، تناول الأول الانسان في اللغة والاصطلاح، في حين تناول الثاني المسار التاريخي لمفهوم الإنسان الكامل.
ثنائيّة التصالح والصراع مع الدهر في شعر أبي مسلم البهلاني
Authors: الحوقاني عيسى , المسعودي علي
Published: February 2024

سعينا في هذه الدّراسة إلى البحث عن ثنائيّة التصالح والصراع مع الدهر في شعر (أبي مسلم البهلانيّ)؛ وذلك بتتبّع كلّ علاقة من هاتين العلاقتين؛ لمعرفة الأسباب التي أدّت إلى تصالح الشاعر مع الدهر تارةً، وتصارعه معه تارةً أخرى، وذلك باستنطاق النصوص الشعريّة وسبر أغوارها، على وفق المنهج الوصفيّ التحليليّ مع الاستعانة بالمنهج الموضوعاتي؛ لتقسيم علاقتيْ التصالح والصراع على حسب الموضوعات، وأولينا الاهتمام بثلاث صورٍ تجلّت فيها علاقة تصالح الشاعر مع الدهر: أولها صورة الزمن الصرف الذي لا يثير أي ردة فعل، وثانيها صورة الفاعل الإيجابي الباعث للرضا والسرور، وآخرها صورة الفاعل السلبيّ الباعث للصبر والتجلّد، وتناولنا علاقة صراع (أبي مسلم) مع الدّهر، وبيّنّا أسباب اختلاف درجات ذلك الصراع وارتباطها بالجانب النفسيّ للشاعر، وكشفنا عن ثلاث صورٍ شكّلت الصراع مع الدهر: أولها الوصف السلبيّ، وثانيها الشكوى، وآخرها المواجهة. وقسم البحث إلى مقدمة وثلاثة محاور هي: علاقة التصالح مع الدهر وـعلاقة الصراع مع الدهر وتحولات الصراع من الشكوى إلى المواجهة.
تخطيط النقل في المراكز الدينية- مركز مدينة كربلاء المقدسة
Authors: ابراهيم مصطفى , محي الدين زهراء
Published: February 2024

تعد مراكز المدن في العالم مقياسا لتفوقها ومراكز لتطلعات ورغبات المجتمع، ولطالما كانت ولا زالت القلب النابض فيها، فهي مركز الأنشطة الاقتصادية والاجتماعية والدينية وان انتشار السيارة و كثرة استعمالها أخذت الدور الرئيس في حركة النقل ولم تترك للسابلة المشاة سوى طرق ضيقة، و لهذا فإن من الضروري الاهتمام بتطويع و ملائمة مركز المدينة لحركة المشاة والسابلة و توفير الأمن لهم في تنقلهم خلال مركز المدينة وشوارعه فكانت مشكلة البحث خطورة حركة المشاة في مراكز المدن الدينية، وذلك بسبب عدم الفصل بين حركة المركبات والمشاة فيها اما فرضية البحث التخطيط السليم للنقل في مركز المدن الدينية يحقق الامن للسكان والزائرين في المدينة القديمة وهدف البحث توفير حركة آمنه وفعالة في مركز مدينة كربلاء المقدسة والجانب العملي يمثل النقل في مركز مدينة كربلاء والمشاكل التي تواجه المركز مثل عدم تنظيم مواقف السيارات وعدم وجود نقل عام مخطط له لذلك وجب وضع حلول لهذه المشاكل لتنظيم النقل في المراكز الدينية.
سد النهضة والأمن المصري
Authors: عيشون حسين , رحيم سراد
Published: February 2024

تهدف هذه الدراسة إلى بيان خطورة سد النهضة على مصر سواءٍ كانت خطورة سياسية أو اقتصادية أو اجتماعية أو أمنية أو بيئية, إذ إن سد النهضة سيؤدي إلى تناقص حصة مصر من مياه النيل الأمر الذي سوف يتبعه العديد من الأثار السلبية بدءاً بتوبير الكثير من الأراضي الزراعية وتهجير الفلاحين فضلاً عن العديد من المشاكل البيئية والاجتماعية وانخفاض كهرباء السد العالي وارتفاع نسبة البطالة نتيجة لتوقف العديد من الصناعات وفقدان عدد كبير من المواطنين لفرص العمل في القطاع الزراعي فضلاً عن الأثار الكارثية الناجمة عن احتمالية انهيار السد كما سيعمل السد على جعل القرار السياسي المصري خاضعاً لإثيوبيا وبالتالي فإن السياسة المائية التي تتبعها إثيوبيا ستؤثر على الأمن الوطني المصري.
تجليات الرجل في شعر نازك الملائكة ولميعة عباس عمارة
Authors: جودي جولان , وناس نجلاء
Published: February 2024

للرجل حضور في شعر المرأة بصفة عامة، وقد يكون مبعث هذا الحضور شعوراً ناتجاً عن انعكاس أثر الرجل الواقعي في حياة المرأة وذاكرتها الثقافية والاجتماعية، أمَّا لدى الشاعرتين؛ نازك الملائكة ولميعة عباس عمارة، فيبدو الأمر مختلفاً، ولم يعد مجرد انعكاس قائم على تجربة شعورية تعتري الشاعرة في لحظة معينة بقدر ما يُشكَّل الرجل تجلِّياً لارتباطات نفسية وفلسفية تثيرها العلاقة المتوترة بين المرأة والرجل، إذْ لم يكن رجلاً نمطياً على طول خارطة الشعر لدى الشاعرتين، وإنما تعدد الرجل بتعدد تجلياته الشعورية وانعكاسهُ المرآوي في نوازع الشاعرة وأحاسيسها والمواقف التي شكلت البنية العميقة لشعرها وهي تختزل تلك الذاكرة الشعرية والرؤية التي تقوم عليها القصيدة أصلاً.

أما ما يبدو في شعر نازك الملائكة ولميعة عمارة فيتصل بكثرة ورود الرجل لديهما وهو ما شكَّل ظاهرة جمالية تستأهل الدراسة؛ ومن ثمَّ سيتناول هذا البحث تجليات الرجل في شعر الشاعرتين، والوقوف على أهم المرتكزات الشعرية لتلك التجليات.
الروايات التفسيرية لآيات الحدود- الزنا والسرقة أنموذجا
Authors: الانصاري عمار , حسين حيدر
Published: February 2024

إن المراد من حدود الله هنا مطلق الأحكام الإلهية التي تحدد حركة الإنسان ضمنها وهي كل فعل حد له الشارع المقدس عقوبة مقدرة وخاصة به كقطع اليد للسرقة والجلد والرجم للزنا وهكذا، وبهذا المعنى الواسع تشمل الأحكام المتغيرة كما تشمل الأحكام الثابتة، ولا شك أن في تشريع الأحكام الإلهية إنما هو من أجل دعوة الناس إلى القسط والعدل وهداية المجتمع إلى الأمن والأمان ليتمكن الناس من كسب الفؤاد والتخلص من الرذائل والوقوف أمام الفساد والفجور والسير إلى مقام القرب الإلهي والذي هو أعلى مقصد للخلق وإقامة الحدود ليس من مختصات زمان حضور الإمام فقط وإنما يجب إقامتها في العصر الحاضر أيضاً.
Risk Factors for CAD Among the Patients with Ischemie Heart Disease- A Cross Sectional Study
Authors: Akhtaruzzaman Muhammed , Hossain Md. Amir , Ahamed Monir Uddin , Zahan Laila Akter , Hossain Mustafa Aolad , Huq Arman Ibne , Karim Md. Rezaul
Published: February 2024

Introduction: Coronary heart disease (CHD) is an impairment of heart function due to inadequate blood flow to the heart compared to its needs, caused by obstructive changes in the coronary circulation to the heart. It is a common multifarious public health crisis today and a leading cause of morbidity and mortality in both developing and developed countries. Objective: To analyses the risk factors for coronary artery disease (CAD) for patients with ischemia heart disease. Methods: A cross sectional study was conducted at Department of Cardiology, Bangladesh Medical College Hospital, Dhaka, Bangladesh from January to December 2022. Total 150 with acute coronary syndrome or coronary angiographic or Electrocardiography evidence of ischemic heart disease. Risk factors studied were the conventional risk factors for coronary artery disease- hypertension, diabetes mellitus, dyslipidemia, body mass index (BMI), smoking, and family history of coronary artery disease Data are collected from the patients, old medical records, Clinical Examination and Laboratory results of the patients were analyzed for the study. Results: A total of 100 (66.6%) patients in the study gave a positive family history for CAD. Based on the blood 'pressure monitoring, the patients were classified according to JNC 7 (reviewed) classification for hypertension as normotensive 78 (78.0%), pre-hypertensive 4(4.0%), stage 1 hypertension was found in 18 patients (18.0%). There was no gender difference noted in the occurrence of hypertension. From the study, diabetes or impaired glucose tolerance (79%) and dyslipidemia (71%) are the major risk factor for Coronary artery disease as only a minority of the study population had hypertension or gives a history of cigarette smoking. 57% of the study population had a family history of coronary artery disease. Among the studied population, 55% of females are with increased BMI, whereas only 16% of males with CAD were with BMI above 30. Conclusion: Among diabetes mellitus and dyslipidemia are the major Risk factor for Coronary artery disease. So early detection of diabetes mellitus and dyslipidemia and proper treatment of both, before developing the end organ damage, play a vital role for the prevention of coronary artery disease.
Impact of Nocturnal Push-Up on Morning Values of Peripheral Oxygen Saturation and Cardiovascular Indices in Young Males
Authors: Adeniyi Mayowa Jeremiah , Idaguko Anna Chika
Published: February 2024

A typical physical exercise is characterized by intensity, frequency, duration and rhythmicity. The study investigated the effect of nocturnal push-up on morning values of peripheral oxygen saturation (SPO2) and cardiovascular indices in apparently healthy males who have neither participated in pushup nor any programmed physical activities in the past three months. 15 apparently healthy young males averaging 16 years executed pushup work-out (44reps/min) between 7pm and 9 pm for a period of 2 weeks. SPO2, blood pressure and pulse rate were measured early in the morning between 6am and 8am 1 week before commencement of workout, two weeks of workout and a week after cessation of workout. Morning values of blood pressure and pulse rate were not significantly affected by either two week of pushup or cessation. However, morning value of SPO2 was significantly increased following 2 weeks of nocturnal pushup. 1week following cessation, SPO2 was not significantly altered. The finding of the study showed the beneficial effect of nocturnal pushup on peripheral oxygen saturations in young males.
Cutaneous Metastasis Revealing Breast Cancer: A Case Report
Authors: Hail Kamel , Belhocine Kafia , Benghanem Lounas , Bouamra Abderrazek , Benyahia Radia , Benlahreche Zakia Batoul
Published: February 2024

Cutaneous metastases are phenomena typically more frequently observed in advanced stages of the disease. However, some cancers can remain clinically silent until the discovery of a cutaneous metastasis, often complicating the diagnosis of the primary tumor, especially if it's a rare tumor like breast cancer in men. It is in this context that we report a case of localized cutaneous metastasis on the scalp, without the presence of other associated clinical signs. Investigations revealed a metastatic breast carcinoma requiring extensive surgical intervention, complemented by adjuvant treatments.
Penile Cancer at the Urology Department of Koutiala Reference Health Center. About Three Cases and Literature Review
Authors: Ballo Bréhima , Berthé Amadou , Koné Ousmane , Dembélé Ousmane , Badiaga Cheickna , Sidibé Youssouf D , Dembé Amadou , Kassogué Souleymane , Diakité Mamadou Lamine , Berthé Honoré JG
Published: February 2024

Goal: Raise awareness among the population to be consulted early in the event of penile cancer and to accept the treatment proposed by the clinician, based on three observations of penile cancer treated in the urology department of the center of reference health Koutiala. Material and methods: This was a prospective review of three cases of penile cancer diagnosed and treated in the urology department of the Koutiala reference health center over a period of two years from January 1, 2021. As of December 31, 2022. The first case was a squamous cell carcinoma of the penile in a 67-year-old patient who suffered amputation of the glans during circumcision, having undergone an adenomectomy in December 2020. The second patient was 63 years old and circumcised; having had urinary bilharzia in childhood and also presenting squamous cell carcinoma. The third case was a 74-year-old circumcised patient with ulcerated swelling of the glans. A review of the literature made it possible to identify the frequency and risk factors and/or precancerous lesions of this cancer on both sides in the world in general and more particularly in Africa. Results: Over a period of two years, three cases of penile cancer were recorded and treated in the urology department of the Koutiala reference health center. The three patients were aged 67, 63 and 74 years respectively. They were all farmers, circumcised and one had his glans amputated during the circumcision. A cystotomy was performed in one patient but all refused amputation of the penis. No patient received radiotherapy or chemotherapy because they were all lost to follow-up. The histological type encountered in our patients was squamous cell carcinoma. Conclusion: Penile cancer remains the least common urological cancer in our practice, behind testicular cancer. Patients are seen late, at stages requiring penile amputation, which few patients accept.
Safety and Efficacy of Various Doses of Tofacitinib among Patients with Active Seronegative Spondyloarthritides – A Retrospective Observational Study
Authors: Saha Sumanta Kumer , Moni Tamanna Taassum , Kadir Md. Rezaul
Published: February 2024

Introduction: Seronegative spondyloarthritides (SpA) are a family of various joint disorders that classically include ankylosing spondylitis (AS), psoriatic arthritis (PsA), inflammatory bowel disease (IBD) associated arthritis, reactive arthritis (formerly Reiter syndrome; ReA), and undifferentiated SpA. Treatment goals for SpA are reducing symptoms, decreasing complications associated with the disease, and reducing functional limitations. Aim of the study: The purpose of this study is to find efficacy and safety of various doses of Tofacitinib, an oral Janus kinase inhibitor, compared with placebo in different stages of the treatment in patients with active Seronegative Spondyloarthritides. Methods: This retrospective observational study was carried out in the Popular Medical College Hospital, Bangladesh. Total 203 subjects of both sexes, aged more than 18 years were selected during the period of May 2023 to November 2023. In this 6 months study duration, patients received 16 weeks treatment (12-week treatment, 4-week washout) and were under follow up session for 8 weeks. Study patients with active SpA phase II were grouped to receive (N=25, 25, 25, 25, respectively) placebo or Jakloc (Tofacitinib) 5 mg and Jakloc (Tofacitinib) XR 11 mg manufactured by Popular Phermaceuticals PLC and Tofacitinib 2 mg or 10 mg (manufactured by other phermaceuticals) twice daily. Jakloc (Tofacitinib) XR 11 mg was used for adult patients with inadequate response or intolerance to methotrexate (3 patients). The primary efficacy endpoint was Assessment of SpondyloArthritis International Society 20% improvement (ASAS20) response rate at week 12. Secondary endpoints included objective measures of disease activity, patient-reported outcomes and MRI of sacroiliac joints and spine after follow up session for 8 weeks. Safety was monitored. Result: The Emax model analysis of the primary endpoint predicted a Jakloc (Tofacitinib) 10 mg twice daily ASAS20 response rate of 67.4%, which ........
Noise Induced Hearing Loss Among Sawmill Workers in a Sub-Saharan African Country
Authors: Yawson Sally Mensa- , Baidoo Kenneth K. K. , Jangu Alhassan Adam , Kitcher Emmanuel D. , Abaidoo Benjamin
Published: February 2024

Introduction: Noise Induced Hearing Loss (NIHL) is a permanent sensorineural hearing loss (HL) which affects the quality of life of exposed individuals. Aim: To determine the prevalence of NIHL among sawmill workers at the Timber market and petty traders in Accra, Ghana, and to assess the difference in actual and self-reported HL among the sawmill workers. Methods: This was a comparative study of NIHL among sawmill workers at the Agbogbloshie Timber Market of Accra and petty traders whose work environment was situated remotely from the sawmill. Data was analysed using SPSS version 20.0. Demographic characteristics and pure tone audiometric testing of study participants were analysed and presented as mean±standard deviation, counts and percentages. Independent T-test was used in comparing pure tone hearing thresholds of sawmill workers and petty traders at various frequencies. Results: A total of 120 sawmill workers and 120 petty traders were studied. Sixty-four (53.3%) of the petty traders were females and all the sawmill workers were males. Mean age of the sawmill workers was 41.5±11.8 years. The prevalence of NIHL among the sawmill workers was 37.5% in the right ear and 43.3% in the left ear. Among the petty traders, the prevalence of NIHL was 12.5% in the right ear and 8.3% in the left ear. There was a statistically significant difference in NIHL between the sawmill workers and the petty traders (p-value = 0.0001). The prevalence of HL in the better ear for the sawmill workers and petty traders was 16.7% and 1.7% respectively. Sixty-nine (57.5%) sawmill workers self-reported HL compared to actual HL of 39 (32.5%) which showed a statistically significant difference (p-value = 0.011). Conclusions: The prevalence of NIHL among the sawmill workers was 37.5% and 43.3% in the right and left ears. There was a significant difference between actual and self-reported HL among the sawmill workers.
Strategy For Controlling Bacterial Leaf Blight (Xanthomonas sp.) on Eucalyptus Pellita Plants by Administering P. aeruginosa RE081
Authors: Marfungah Siti , Puspita Fifi , Tjahjono Budi , Alhusaeri Siregar Bayo , Gafur Abdul
Published: February 2024

The demand for Eucalyptus Pellita seeds as a high-throughput inoculum (HTI) crop commodity in the field is extremely high. However, Xanthomonas sp., a bacteria that causes bacterial leaf blight, poses a significant challenge in ensuring a steady supply of healthy seedlings in nurseries. Researchers have explored using the rhizobacteria P. aeruginosa RE081 as an environmentally friendly biocontrol agent to address this issue. This study aims to determine the optimal concentration of P. aeruginosa RE081 that can effectively reduce the incidence and severity of bacterial leaf blight caused by Xanthomonas sp. The research was conducted using a completely randomized design, with different concentrations of P. aeruginosa RE081 (105, 106, 107, 108 CFU/mL) being tested. The findings indicate that the biological agent's concentration significantly impacts plant disease occurrence and severity. In vivo testing revealed that P. aeruginosa RE081 reduced disease severity by only 2.13% at a 108 CFU/mL concentration. Interestingly, concentrations lower than 108 CFU/mL increased disease severity compared to the control group.
EVALUASI PENGGUNAAN ANTIBIOTIK DENGAN METODE GYSSENS PADA PASIEN DEMAM TIFOID ANAK DI INSTALASI RAWAT INAP RSUP Dr. SITANALA TAHUN 2019-2021
Authors:   Universitas Muhammadiyah A.R. Fachruddin, Megawati Sefi , Nuraini Nuraini , Carolina Febby
Published: February 2024

Typhoid fever is a disease caused by bacteria and its treatment requires antibiotics. Antibiotic-resistant bacteria can grow as a result of improper use of antibiotics. The purpose of this study was to determine the rational usage pattern and percentage of antibiotic drug use according to the Gyssens method. This non-experimental study employed retrospective data collecting from the medical records of children treated for typhoid fever at the Dr. Sitanala in 2019â€“2021 and used the Gyssens technique for analysis. According to the study's findings, 28 patients (46.67%) were classified as irrational, whereas 32 patients (53.33%) were considered rational (category 0). In this study, it can be concluded that the use of antibiotics used in typhoid fever patients, namely ceftriaxone (82,54%), cefotaxime (14.29%), and cefixime (3.17%) with the intravenous route of administration (96.83%) and orally (3.17%). Irrational use of antibiotics included Gyssens category V (antibiotics are not needed) (1.67%), category IVC (there are cheaper antibiotics) (11,86%), category IIIB (the duration of giving antibiotics are too short) (30,51%), category IIA (not the right doses) (20,34%), and category I (not on time to give antibiotics) (18.64%).
EFEKTIVITAS ANTIBAKTERI EKSTRAK DAUN KECAPI (Sandoricum koetjape Merr) TERHADAP PERTUMBUHAN BAKTERI Enterococcus faecalis
Authors:   Universitas Lambung Mangkurat, Wasiaturrahmah Yusrinie , Rayhan Muhammad , Tri Putri Deby Kania , Wardhana Agung Satria , Apriasari Maharani Laillyza
Published: February 2024

Penyebab terbesar kegagalan perawatan saluran akar sebesar 63% disebabkan oleh bakteri Enterococcus faecalis. Bakteri Enterococcus faecalis dapat dieliminasi dengan melakukan irigasi saluran akar. Kandungan zat aktif seperti saponin yang terdapat di dalam daun kecapi (Sandoricum koetjape Merr) terbukti memiliki efek antibakteri. Tujuan mengukur dan menganalisis efektivitas antibakteri ekstrak daun kecapi (Sandoricum koetjape Merr) terhadap pertumbuhan bakteri Enterococcus faecalis. Metode penelitian ini merupakan eksperimen murni (true experimental) dengan post test only with control group design. Penelitian ini terdiri dari 9 kelompok perlakuan, yaitu ekstrak daun kecapi (Sandoricum koetjape Merr) konsentrasi 10%, 20%, 30%, 40%, 50%, 60%, 70%, sodium hipoklorit (NaOCl), dan aquadest dengan 3 kali pengulangan. Data KHM didapatkan dari pengukuran delta Optical Density (OD) dan data uji KBM didapatkan berdasarkan perhitungan jumlah koloni. Berdasarkan nilai rata-rata dan analisis data diketahui KHM terdapat pada konsentrasi ekstrak daun kecapi 10% dan KBM pada konsentrasi 20%. Ekstrak daun kecapi (Sandoricum koetjape Merr) konsentrasi 10%, 20%, 30%, 40%, 50%, 60%, dan 70% memiliki efektivitas antibakteri terhadap pertumbuhan bakteri Enterococcus faecalis.
EVALUASI PENGELOLAAN PENYIMPANAN SEDIAAN FARMASI DI GUDANG INSTALASI FARMASI RSIA IBUNDA PELAIHARI
Authors: Ilahi fitrah shafran , Aprilia Tia Nor , Yumassik Abdul Mahmud , Wahyuni Amaliyah
Published: February 2024

Drug storage in hospital pharmacy installations is a guarantee of the feasibility of drugs received by the hospital before being distributed to patients.Â pharmaceutical preparations used by the pharmaceutical installation warehouse at RSIA Ibunda Pelaihari based on the quality standards of the Minister of Health regulation number 72 of 2016 concerning service standards in hospitals. The research method uses a qualitative observational method, the research instrument used in data collection is an observational sheet. The results showed that the storage of pharmaceutical preparations in the pharmaceutical installation warehouse of RSIA Ibunda Pelaihari obtained a figure of 92% which was included in the good criteria based on the results of the calculation of the observation sheet carried out in the pharmaceutical installation warehouse of RSIA Ibunda Pelaihari by showing parts that were in accordance with the Permenkes standard number 72 of 2016, namely storage components, storage system, storage method. While as many as 8% that have not met the standards are the storage requirements and storage equipment. The storage of pharmaceutical preparations in the pharmaceutical warehouse of RSIA Ibunda Pelaihari has met the standards of Permenkes number 72 of 2016 with a percentage of 92% which is in the good category.
Energy Access in the Village of Gunung Arba, Jango Village from the Perspective of Environmental Justice in Central Lombok District Community
Authors: Jannah Raodatul , Hidayat Agus Rohmat
Published: February 2024

Environmental justice from the perspective of public participation in the development of natural resources is a national program where the government is starting to switch from fossil energy to green energy, which means that in the future the government will no longer hope for energy such as coal, oil and gas, etc. This is a very strategic step taken by the government. Centralized is the antithesis of the increasing pressure to decentralize regional government, including regarding the management of natural resources (SDA) policies in the mining and oil and gas sectors, To ensure that this program runs well, of course the community is involved in monitoring it. Community participation in sustainable development is indeed weak, including in terms of policy making, even though the laws and regulations also stipulate that the community has rights as explained in the Aarhus Convention, where parties have an obligation to guarantee the right of access to information, community participation in decision making, and access to justice in environmental matters in accordance with the provisions of the convention. Then in Law No. 32 of 2009 concerning Environmental Protection and Management, it is intended, among other things, 1) to provide information to the government, 2) to increase the public's willingness to accept government decisions. 3) Helps with legal protection. and 4) Democratize decision making. From the above basis, it further strengthens the community so that it can participate actively in the development of natural resources in this country.
Harmonizing Cross View Image Transformation Through Local and Global Insights- A Review
Authors: Sowmiya T. , Gopal M. Madhana , Marimuthu V. , Santhosh P.
Published: February 2024

Hyperspectral and multispectral information processing systems and technologies have demonstrated their value in enhancing agricultural productivity and practices by providing farmers and crop managers with valuable information on factors influencing crop condition and growth. These technologies play a crucial role in various agricultural applications, such as crop management, crop yield forecasting, crop disease detection, and monitoring soil, water, and land usage. To enhance the process of agriculture through effective crop management and assistance to farmer, using an advanced image transformation techniques the study delves into the exploration of techniques for harmonizing cross-view image transformation, with a focus on integrating both local and global insights. Further the study proposes the application of the 2D-DWT (Two-Dimensional Discrete Wavelet Transform) technique for image data preprocessing and the Extreme Learning Machine (ELM) algorithm for image classification in the context of hyperspectral images. Hyperspectral information sensing allows for the coverage of the electromagnetic spectrum in a single acquisition with several hundred spectral bands, resulting in a data cube containing significant spectral and spatial information ELM is particularly effective for classification problems because of its quick training time and capacity to operate with hidden nodes whose parameters are randomly assigned rather than modified iteratively. This comprehensive review aims to provide valuable insights and a critical analysis of the suggested method, shedding light on its potential contributions to the advancement of image transformation techniques for agricultural development.
AI-based Voice E-Mail System for Visually Impaired
Authors: Narayanee N. P. Shangara , Nathiya M. , Vihashini V. Preethi , Veeramani G.
Published: February 2024

Electronic communication tools, such as email are visual in nature, and accessing as well as using them might be difficult for visually impaired people. This research present an email communication system designed to beeasy to use and accessible, aiding individuals in overcoming obstacles associated with visual impairment The suggested method transforms the text-based email communications into speech using natural language processing algorithms, in order to makes it simpler for those with visual impairments to understand and reply to the emails received. Additionally, the system incorporates the speech-to-text technology, enabling users to dictate and send emails using their voice. To assist users, write emails that are more accurate and readable, the system may also be set up to offer recommendations and edits to them while they are writing them. Over time, the system can offer more precise and pertinent recommendations by using machine learning algorithms to learn from user interactions. The proposed study involves an in-depth review of existing methods designed to assist the visually impaired. Additionally, the study introduces a suggested method aimed at enhancing email communication for individuals with visual impairments.
IMPACTO DA FISIOTERAPIA MOTORA NA PREVENÇÃO DE COMPLICAÇÕES MUSCULOESQUELÉTICAS EM PACIENTES CRÍTICOS NA UTI
Authors: Kundsin Alana , Paula Alex Blank de , Spiguel Larissa Claro , Cardoso Renan Sesquim
Published: February 2024

A fisioterapia motora desempenha uma função essencial na promoção da saúde e na reabilitação de pessoas impactadas por diversas condições que afetam o sistema musculoesquelético. De acordo com a estratégia PICO, levantou-se o seguinte questionamento: Em pacientes críticos em UTI, qual é o impacto da fisioterapia motora na prevenção de complicações musculoesqueléticas? O trabalho teve como objetivo elucidar o impacto da fisioterapia motora na prevenção de complicações musculoesqueléticas no âmbito intensivo. Para isso, realizou-se uma revisão bibliográfica do tipo integrativa, descritiva, apoiando-se nas bases de dados Scielo, Lilacs, PubMed e google acadêmico. No geral foram utilizados 14 artigos científicos que ofereceram as bases teóricas da investigação e que estavam ligados diretamente ao tema. Para a pesquisa nas bases de dados foram utilizados os operadores booleanos “and” “or” e “not”. O trabalho destacou a importância da fisioterapia motora na prevenção de disfunções musculoesqueléticas e seus benefícios, entretanto, na prática ainda precisa de mais incentivo para a ampliação da prática.
Strategi Peningkatan Keterampilan Masyarakat Dalam Membangun Package Backend dan Frontend
Authors: Putri Ardiva , Youzanna Gabriella , Fathonah Nyi Raden Nuraini Siti
Published: February 2024

Community Service (PKM) with the theme "Strategy for Increasing Community Skills in Building Backend and Frontend Packages" was carried out through a zoom meeting on December 3 2023. This activity aims to provide in-depth understanding and practical skills to teenagers around Bandung City in developing software applications . The seminar began with an explanation of the basic concepts of Package Backend (BE) and Frontend (FE), followed by practical training that involved active participation of participants in building real projects. The implementation method uses a community activity center to facilitate access and create an interactive space. The target audience consists of teenagers from Bandung City, selected because of their potential to develop technological skills. Indicators of success include active participation, understanding of the material, and participants' practical abilities in building applications. Evaluation methods include written exams, practical projects, and participant satisfaction surveys. The results showed significant improvements in participants' understanding and practical skills. Positive impacts can be seen from the small projects that participants develop after the training, creating a stronger technology ecosystem at the local level.
Strategic determinants of international economic activity development in the context of digitization
Authors: Proskurnina Nadiia , Tymoshenko Karyna
Published: February 2024

Due to the rapid development of digital technologies, the international economic sphere is facing significant changes and challenges. Digital innovations are permeating all aspects of business, from management to marketing, from logistics to customer communication. One of the key determinants of this process is constant technological progress, which stimulates the adoption of new tools and strategies. Enterprises operating in the international market are compelled to adapt to this new environment by improving their processes, optimizing production, and enhancing efficiency. Digital technologies enable the automation of many processes, making businesses more flexible and competitive. However, along with the advantages of digitization come new challenges. Cybersecurity becomes increasingly relevant as companies must protect their data from cyber attacks and information leaks. Regulatory issues are also becoming more complex, as the legal environment does not always keep pace with the speed of technological development. Moreover, ethical questions arise regarding the use of personal data and the impact of technologies on society. The article highlights the main strategic determinants and drivers that contribute to the development of international economic activity in the context of digitization. It synthesizes a range of factors and forces that encourage the adoption and integration of digital technologies and practices across various sectors of the global economy. It is demonstrated that the driving forces of digitization in international economic activity are interconnected and reinforce each other, while technological progress shapes a new paradigm of consumer behavior and expectations, stimulating demand for further technological innovations. The main problems and challenges faced by enterprises in the global market in the context of digitization are analyzed and summarized. In the digital age, it is important to have an open mind and be prepared for constant change. Enterprises that successfully integrate digital technologies into their strategy can gain a significant competitive advantage in the international market. However, this requires continuous improvement and readiness for innovation.
Keywords: digitization, digital economy, globalization, organizational and economic support, international economic activity.
Water resources management in the context of the circular economy concept
Authors: Boyko Yevgenia , Parsyak Volodymyr , Irtyshcheva Inna , Kramarenko Iryna
Published: February 2024

The article examines the essence and main goals of the circular economy. The connection between the circular economy and the achievement of the goals of sustainable development has been studied. The positive effect of the introduction of the circular economy for the social, economic and ecological system was determined. Reducing the scarcity of natural resources, as well as the creation of durable goods, allows reducing the negative impact on the environment, which in turn stimulates innovation, which increases competitive advantages in international markets. The peculiarities of the development of circular economy models in developed countries are considered. The peculiarities of the economic category of water and its role in the economy are analyzed. The different roles of water emphasize its uniqueness and prove the difficulty of adopting a unified approach to it in the circular economy. The dynamics of indicators of the water capacity of Ukraine's GDP and volumes of return (waste) water discharged into surface water bodies were analyzed. It was determined that the rethinking of the urban water supply system through the principles of the circular economy and the goals of sustainable development will reduce the amount of polluted water and increase its reuse. It was determined that Ukraine is one of the least water-supplied countries in Europe, the annual runoff reserves available for use per person do not exceed 1,000 m3, while the GDP water capacity indicator remains sufficiently high and exceeds its target value. The dynamics of the indicator of the water capacity of the GDP of Ukraine has been analyzed, it has a tendency to decrease for the years 2015-2022. The characteristic problems of the functioning of urban water supply and drainage systems in the front-line territories and safer cities, where the number of internally displaced people has increased, are analyzed. It was analyzed that not all classic circular economy strategies can be applied to water. Strategies of the circular economy of water are considered and it is emphasized that rethinking is inherent in all water strategies. It has been analyzed that the implementation of the circular economy may face financial, bureaucratic and behavioral problems and regulatory, legislative, managerial and implementation obstacles.
Keywords: circular economy, water resources, sustainable development, integrated management of water resources, state policy, goals of sustainable development, strategies, economic model, water supply and drainage system
Directions of updating the cultural heritage of Roztochchia in the conditions of war
Authors: Popovych Yaroslava
Published: February 2024

The relevance of cultural and educational activities to ensure the promotion of the Ukrainian Roztochchia region has been analyzed. In connection with the processes of decentralization, a number of problems arise with the passporting of objects of cultural heritage, innovations in document circulation, etc. Active military actions on the part of Russia lead to large‒scale destruction or complete destruction of the artistic heritage of certain regions of Ukraine. In the current conditions, measures for security, fixation, preservation and promotion will be of great importance in the cultural and artistic space both for a separate region and for the state as a whole. The need to capitalize the resources of cultural strategies has become especially acute during the 2022-2023 war, a time when the issue of heritage preservation is a priority at all levels of state formation.
The opening of cross‒border road connections between Ukraine and Poland created favorable conditions for the development of tourism. This allows increasing tourist flows, especially from European countries to Lviv, and also requires the development of tourist infrastructure on both sides of the border: hotels, cafes, eco-stops, agro‒villages, etc. Cross‒border tourism has covered only the roadside (along the main transport arteries) part of the Roztochchia region, but the majority of artistic attractions, namely the heights of Roztochchia, remain outside the international tourist flows. The lack of land border crossings, information sources about tourist routes, insufficient provision and low standard of logistics services, especially from the Ukrainian side, lead to the leveling of cultural heritage and its promotion. International projects, competitions and grants will be important factors supporting the development of artistic processes in the region. High civic consciousness and the activity of cultural institutions will lead to significant positive changes in the issues of preservation and promotion of regional features, their identity and uniqueness.
Standardism Performance of Dental Workers and Infection Control Status of Corrective Patient Instruments
Authors: Na Hee Ja
Published: February 2024

Objective: This study aims to understand the performance of standardism through the performance of orthodontic workers and the infection control of orthodontic patients, and to contribute to the improvement of oral health of orthodontic patients and provide it as academic basic data. Methods: A study was conducted on 111 dental workers working at dental clinics in Gwangju Metropolitan City and Gyeonggi-do from March 1, 2023. The number of students participating in the study was calculated as the G. power 3.1 program, with an effect size of 0.3, a significant level of 0.05, and a power of 0.95. Participants in the survey understood the purpose of the study and agreed to participate in the study, and a self-written survey was conducted. The questionnaire was measured on a Likert 5-point scale, and 5 points were given to "very important" on the Likert 5-point scale and 1 point to "not important" so the higher the score, the higher the degree of practice. Results: Number of sterilizations of braces * In cross-analysis of clinical experience, sterilization was most common once a week, followed by sterilization once every two weeks. It can be said that there is no significant difference in the number of times and clinical experience. Conclusion: Clinical experience and regression analysis of instrument sterilization showed minimal levels of clinical experience, contaminated instrument management, hand hygiene, personal protective equipment, respiratory etiquette, and instrument sterilization methods.