bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessment Vulnerability Index of West Coast of South Sulawesi, Indonesia: A Case Study in Segeri Beach, Pangkajene and Islands Regency
Authors: Paharuddin  , Alham Irawan
Published: May 2023

The coastal area of Segeri Sub-district, Pangkajene and Island Regency, as one of the areas along the West Coast of South Sulawesi, is a zone prone to the natural phenomenon of sea level rise. The impact of this phenomenon needs to be studied to identify the level of coastal vulnerability and project changes in coastal vulnerability in the future. The research aims to calculate the coastal vulnerability index and project changes in vulnerability in the future due to changes in factors that affect coastal vulnerability. This research was conducted for five months at Bone-Village Beach of area Bawasalo and Bontomatene Segeri Sub-district, Pangkajene and Islands Regency, South Sulawesi, Indonesia. The method of data analysis carried out is the Analysis of coastal ecosystems and resources, analysis of physical and social characteristics of the community, and analysis of coastal environmental vulnerability with the Vulnerability Scoping Diagram (VSD) model that places exposure, sensitivity, and adaptive capacity as dimensions of Vulnerability Index. The components of the exposure dimension consist of coastal dynamics, natural disturbances, and population. Components of the sensitivity dimension are coastal characteristics, land use, and human settlements. The adaptive capacity dimension includes coastal habitat and marine conservation areas. Based on the score of each parameter in the three dimensions, the Coastal Vulnerability Index (CVI) of all observed locations is in the range of CVI values 7.96 - 9.59, which means the category of Moderate Vulnerability. Factors that strongly influence the CVI are the sensitivity dimensions, including Erosion, waves, and tides caused by oceanographic factors so; that if The Segeri Coastal Area does not make adaptation and mitigation efforts, then the possibility of the next 5 - 10 years, the level of Coastal vulnerability Index can be a high or very high Vulnerability. Adaptation efforts that can be made are strengthening the coastal boundary area, planting and expanding mangrove trees in the Segeri coastal area.
The Development of Social Science Learning Media Based on Wordwall Digital Game in Elementary Schools
Authors: Rahman Syarifah Aeni , Bundu Patta , Samad Sulaiman
Published: May 2023

This study aims to (1) describe the need for the Development of social science learning media based on digital game word walls in elementary schools; (2) know the description of social science learning media design based on digital word wall games for elementary school students ; (3) know the description validity of digital game word wall- based social science learning media for elementary school students ; (4) knowing the practicability of social science learning media based on the digital game word wall for elementary school students ; (5) knowing the effectiveness of social science learning media based on the digital game word wall in improving student learning outcomes at Elementary Schools. This type of research is Research and Development (R & D). The research and development procedure used is 4-D: define, design, develop and disseminate. The subjects of this study were fourth-grade students at SD Negeri Minasa Upa Makassar, consisting of 31 students and two teachers. Data was collected through test techniques, observation, and questionnaires. The data analysis technique used is quantitative analysis according to the research and development stage. The results of this study indicate that : (1) The need to develop social science learning media based on the digital word wall games is a fundamental demand in the digital era in learning where challenging and fun interactions are needed in the form of word wall games for elementary school students; (2) Social science learning media based on the digital word wall games are designed through the stages of selecting games, compiling quizzes, selecting formats, initial design, and limited trials; (3) digital word wall game- based social science learning media has an adequate level of validity in all components. The display aspect of word wall game digital media, stages, and tests obtained the maximum value from the validator. (4) Social science learning media based on digital game word walls fulfill the practicability requirements through the positive response of teachers and students, which is marked by increased student activity in learning. (5) Social science learning media based on digital game word walls is practical for social studies learning, marked by increased student learning outcomes through pretest and posttest.
Teacher’s Sense of Efficacy and Students’ Motivation: The Mediating Effect of Parental Involvement
Authors: Buat Maryam Dessa H. , Limpot Marilou Y.
Published: May 2023

Aims: To determine the mediating effect of parental involvement in the relationship of teacher’s sense of efficacy and students’ motivation.

Study Design: Quantitative non-experimental design.

Place and Duration of Study: The study was conducted among secondary school teachers in all public schools in the Division of Davao del Sur, Region 11, Mindanao, Philippines during the school year 2021-2022.

Methodology: The respondents were 308 secondary school teachers from the Division of Davao del sur, selected using stratified random sampling. The data were collected using google forms. Mean, standard deviation, Regression Analysis, and Medgraph using Sobel z-test were used to analyze the collected data.

Results: The overall results showed that the study had very high mean of teacher’s sense of efficacy, high mean of students’ motivation and very high mean of parental involvement. From the significant relationship of each variable, parental involvement partially mediates the relationship between the teacher's sense of efficacy and the students’ motivation. There is not only a significant relationship between parental involvement and teacher's sense of efficacy but there is also a direct relationship between the teacher's sense of efficacy and students’ motivation.

Conclusion: The results proved that the teacher’s sense of efficacy directly affects the students’ motivation with the influence of parental involvement.
Biodiversity and Community Structure of Arboreal Foraging Ants (Hymenoptera: Formicidae), Mealybugs (Hemiptera: Sternorrhyncha: Coccoidea) and Host Plants in Douala, Littoral-Cameroon
Authors: Kayoum Yomon Abdel , Boris Fouelifack-Nintidem , Agrippine Yetchom-Fondjo Jeanne , Junior Tsekane Sedrick , Babell Ngamaleu-Siewe , Laure Kenne Edith , Mohammadou Moukhtar , Kenne Martin
Published: May 2023

Aims: Mealybugs are protected on plants by ants for honeydew. They were identified and assemblages were characterized in Douala suburbs (Littoral-Cameroon).

Study Design: Basic information is needed on pest’s occurrence for the pest control strategies. We determined host plants and characterized the community structure of mealybugs and foraging ants.

Place and Duration of Study: Field investigations were conducted from March to August 2020 in Douala suburbs in 16 transects (10x1,260 m each) and 126 quadrats (10x10m each).

Methodology: Stems, the underside of leaves, flower buds and fruits were inspected on weeds, plant bases and canopy of trees. Mealybugs and ants were captured. When the plant was highly infested, the average number of insects was determined on 10 randomly chosen plant organs. Abundances were noted and captured specimens were stored in vials containing 70° alcohol, identified to the species level and the community structure was characterized.

Results: A total of 24,640 specimens belonged to 23 families, 54 genera and 85 species were collected in this research. A low species richness, low diversity and low dominance were detected. Assemblage of foraging ants in Yassa functioned according to the brokend-stick model. Scale insects in Ngoma functioned according to Motomura’s model. Assemblages of host plants in Lendi, Yassa, global host plants, global scale insects, foraging ants in Lendi and the global settlement, functioned according to the lognormal model. Host plants in Ngoma, scale insects in Yassa, and foraging ants in Ngoma functioned according to Zipf’s model while Zipf-Mandelbrot was adapted to scale insects in Lendi suggesting that these communities had sufficient time to develop a complex network of information close to natural environments and presented a fairly regeneration force.

Conclusion: Due to the abundance pest insects, resources are available and once they will be well developed; they will cause plant pathologies and yield loss.
A Case Series on COVID-19 Associated Mucormycosis (CAM): Experience from a Tertiary Care Centre in India
Authors: Govindaswamy Aishwarya , Sridharan Sowmya , Savio Raymond Dominic , Nambi Senthur , Rajendran Adhithyan
Published: May 2023

Aim: During the second wave of the COVID 19 pandemic, a life threatening fungal infection, mucormycosis have been detected in patients post COVID 19 disease. Commonly known as the ‘black fungus’ can causes tissue necrosis, inflammation and necrosis of the head and neck regions, paranasal sinuses, facial bones, orbits and it can also cause intracranial spread. In the current study we describe a series of cases of COVID 19 associated mucormycosis (CAM), the clinical presentations, risk factors, diagnosis, management and follow up experience from a tertiary care centre in India.

Methods: This is a retrospective observational study conducted over a period of one year (April 2021 to April 2022) at our tertiary care centre. The diagnosis of COVID 19 was done by RT PCR (reverse transcription-polymerase chain reaction). The diagnosis of Mucormycosis was done by Histopathology and fungal cultures. The demographic details of the patients were retrieved from the medical records.

Results: In the present study we report four cases of Rhino-orbital-cerebral Mucormycosis, three cases of Rhino-orbital Mucormycosis, two cases of Pulmonary Mucormycosis and one case of Disseminated Mucormycosis. All the patients had undergone extensive surgical debridement and received Liposomal Amphotericin B as initial antifungal medication and Posaconazole or Isavuconazole as step down therapy. Six patients responded to treatment while four patients did not have a favorable outcome and succumbed to the illness.  

Conclusion: Mucormycosis is a deadly disease with high mortality and morbidity if not diagnosed and treated at an early stage. Factors like poor control of blood sugars, inadvertent use of corticosteroids, immune dysfunction due to COVID 19 can result in poor outcome of the disease despite aggressive treatment interventions.
Avoiding Hunger during Crisis Situation in Philippines: The COVID 19-Challenges
Authors: Bergonio Emerson L.
Published: May 2023

People’s livelihoods and other assets of the people concerning agricultural production and food supply are currently being affected by COVID-19 crisis. Change in both food production and consumption may be expected and this will require urgent and critical decisions on how to prevent the threat of food/resource scarcity and hunger including risks to biodiversity, health and well-being of households within the poverty threshold.
Ethnopharmacological Characteristics of Pycnanthus angolensis (Welw.) Warb. (Myristicaceae), a Plant Used in the Traditional Treatment of Viral and Parasitic Diseases
Authors: Bene Kouadio , Azokou Alain , Kouame Kouassi Bernadin , Fah Monh Alice , Traore Inna Tata , Koné Mamidou Witabouna
Published: May 2023

Background: Pycnanthus angolensis (Welw.) Warb. (Myristicaceae) is a medicinal plant used in traditional Ivorian medicine. A recent ethnobotanical survey has discovered Pycnanthus angolensis in the traditional treatment of viral and parasitic diseases.

Aim: The present study aims to highlight the distinctive ethnopharmacological characteristics of Pycnanthus angolensis.

Methods: The aim was to identify some groups of chemical compounds by thin layer chromatography, to assay some minerals and finally to characterise the specific anatomical and micrographic features of the plant.

Results: Terpenes and sterols, saponosides, flavonoids and tannins are the main phytocompounds revealed. Magnesium with 621.3 mg/100 g dry matter is the most abundant mineral. Anatomical sections and plant powder revealed starch grains, calcium oxalate crystals, secretory pockets and tector hairs that are responsible for the formation of various biological substances in the plant.

Conclusion: These results add to the data on Pycnanthus angolensis, a taxon much used in traditional Ivorian medicine for the treatment of antiparasitic and antiviral diseases.
Analysis of Socio-Economic Characteristics of Potato Farmers and Trend, Growth Rate of Area, Production of Potato in Nalanda District of Bihar, India
Authors: Kumari Suman , Maurya Mukesh , Kumar Sanjay , Noel Ashish S.
Published: May 2023

This paper investigates the socio–economic situation of potato farmers and the Growth Rate of Area, Production of Potato in Nalanda District of Bihar, India. Nalanda district was purposively selected because this district has a maximum area under potato cultivation. The required data were collected from 150 randomly selected farmers for the year 2021-22. The average size of land holding and the family size was 1.51 ha. and 5.7 respectively in the study area. Potato farmers are categorized into three different age groups i.e., Below 30 years, 30-50 years and Above 50 years. The majority of farmers (40%) fall into 30-50 age group. Medium farmers are the highest annual income as compared to small and marginal farmers. The result shows that the annual income of farmers consists of farm and non-farm sources i.e., 40% and 60% respectively. The trend analysis shows that the growth rate in area and production was negative during periods I (2007–08 to 2011–12) and II (2017–18 to 2021–22), while the growth rate of area and production was positive during periods III (2012–13 to 2016–17). There was a positive trend with annual growth rates of 2.85 percent for area, 0.86 percent for production during period III and 8.82 percent and 2.19 percent for yield during the period of 2007-08 to 2017-18.
Genetic Divergence Study in Different Rice (Oryza sativa L.) Genotypes under Irrigated and Drought Stress Condition
Authors: Bora Sirisha , Manjunath Manthur Sreeramulu , Kumar Vinod , Sulochna  , Maurya C. l. , Sachan Dhruvendra Singh , Koshariya Ashok Kumar
Published: May 2023

Thirty rice genotypes were evaluated to study genetic divergence under irrigated and drought stress conditions in randomized block design at Bagusala farm, M. S. Swaminathan School of Agriculture, CUTM, Odisha, during summer 2019. The main objective of this experiment was to identify reproductive phase drought tolerant genotypes through study the effect of drought stress on yield, yield attributing and biochemical traits performance of selected genotypes using Mahalanobis D2 statistics. Set of 30 genotypes were grouped in to five and nine clusters under irrigated and drought situation. Under irrigated conditions cluster-Ⅰ was largest cluster with 22 genotypes followed by cluster-Ⅱ includes 5 genotypes cluster-Ⅲ, IV and V each consisted with only one genotype. Under drought condition, genotypes were grouped into nine different clusters, cluster-Ⅰ was the largest cluster involving 20 genotypes followed by cluster-Ⅱ having 3 genotypes whereas, cluster-Ⅲ, IV, Ⅴ, Ⅵ, Ⅶ, Ⅷ and Ⅸ were recorded with single genotype. The maximum intra cluster distances under irrigated conditions were found in cluster- Ⅱ (27111.9) followed by cluster-Ⅰ (17587.7). Whereas, in case of stress cluster-Ⅱ had maximum distance (21110.9) fallowed by cluster-Ⅰ (17957.8). Under irrigated maximum inter-cluster distances recorded between cluster-Ⅱ and Ⅴ (62310.8) followed by cluster-Ⅳ and Ⅴ (57656.0). In case of stress maximum inter cluster distances recorded between cluster -Ⅱ and Ⅶ (69865.5) fallowed by cluster- Ⅷ and Ⅸ (67848.9), cluster-Ⅱ and Ⅸ (65239.2). Under irrigate conditions highest manifestation towards genetic divergence was exhibited by chlorophyll followed by plant yield, 1000 grain weight, proline, number of spikelets, carbohydrates, grain weight, phenols, panicle length, panicle weight, flavonoids, number of filled grains, plant height and number of tillers. In case of drought stress, maximum percentage contribution towards to the genetic divergence was observed for Proline followed by carbohydrates, plant height, plant yield, grain weight, chlorophyll, number of spikelets, flavonoids, 1000grain weight, filled grains, phenols, panicle weight, panicle length and number of tillers, while other trait like root length did not contribute to the total divergence. The genotypes grouped under cluster Ⅰ, Ⅲ, Ⅴ, Ⅷ namely MTU1010, MTU1075, MTU1224, RNR2465 and Manipur black rice exhibited maximum drought tolerance under stress conditions. These genotypes can be used as the donor parents for development of drought tolerant lines in crop improvement programme.
Evaluation of Rice Varieties (Oryza sativa L.) on the Basis of Physiological and Morphological Traits
Authors: Singh Saurabh , Singh A. K. , Singh Shraddha , Singh Alok Kumar
Published: May 2023

The investigation entitled “Evaluation of rice varieties (Oryza sativa L.) on the basis of physiological and morphological traits” was conducted during the Kharif season, 2019-2020 at the field of Student’s Instruction Farm, Acharya Narendra Deva University of Agriculture & Technology, Kumarganj, Ayodhya. Nine elite rice genotypes were shown in RBD with three replications, and morphological data were recorded. i.e., Plant height (cm), tiller number per plant, ear bearing tillers per plant, dry weight per plant(g), number of grains/plant, test weight(g), grain yield per plant. The plant height was, plant dry weight and number of tillers per plant obtained maximum in Sambha Sub-1 in comparison to other genotypes.
Response of Foliar Spray of Iron and Gibberellic Acid on Growth and Yield of Greengram
Authors: Topno Michael William , Dawson Joy
Published: May 2023

The Field experiment was conducted during Kharif season, 2022 at Crop Research Farm, Department of Agronomy, Sam Higginbottom University of Agricultural Sciences, Prayagraj, U.P, India. To evaluate the Response of Foliar spray of Iron and Gibberellic acid on the Growth and Yield of Greengram . The Soil of the experimented field was Sandy Loam in texture, slightly alkaline reaction (pH 7.0), low in organic carbon (0.40%), available N (161.48kg/ha), available 151.2kg/ha) and available K(232.5kg/ha).The Treatment consisted of FeSO4 (foliar spray at 15,30 DAS) 0.5%, 1.0% and 1.5% ,and GA3(foliar spray at 20,40 DAS) 50ppm, 100ppm, and 150ppm . The experiment was laid out in a randomized Block design and comprised of different levels of Iron and GA3 with ten treatments and replicated thrice. The growth attributes which was plant height (53.83cm), No. of Nodules/plant (51.00), Plant dry weight (11.67 g/plant) was significantly increased with increase in level of Iron and GA3.The Yield attributes was obtained Maximum, No. of Pods/Plant (24.5), No. of Seeds/Pod (12.00), Test weight (20.50g), Grain yield (1.95 t/ha), Stover Yield (3.15 t/ha) and Harvest Index (33.83%)at harvest. Maximum Gross Return (INR 1,29,112.50 INR/ha), Net Return (INR 92,803.50 INR/ha), highest B: C Ratio (2.56).
Artificial Neural Networks and their Use in Agricultural Genetic Engineering and Protein Estimation
Authors: Kotiyal Amit , Dudi Aashish , Lakshmi M. , Gaurav Adesh , Shah Bikram , Mondal Ritam , Kadu Lalit , Kalyan Nitin
Published: May 2023

A mathematical model called an artificial neural network uses certain algorithms to anticipate and predict various events. This model has multiple layers, including input, hidden, and output layers. By altering its algorithms, various outputs can be produced based on the input utilized. Biological neuron mechanization has an impact on artificial neural networks. As biological neurons have a propensity to learn and train sets of data for producing biased outputs by spotting and removing variances in them, ANN also works on these principles. Although this model has many uses, it has historically been employed in biological experiments using the supervised learning method, one of which is to predict protein secondary structure. This allows one to identify the positions of different amino acids that are ordered complicated protein structures, which are very appealing in genetic engineering. By this model scientists can map out and isolate a desirable gene in genetic material without going through intense laborious experiments. This report summarizes all the objectives linked to artificial neural networks as well as their applications in bioengineering by examining many related studies.
Effect of Low Cost Storage Structure on Shelf Life and Quality of Onion Genotypes
Authors: Kumar Hitesh , Dhankhar S. K.
Published: May 2023

The effect of fully ventilated storage structure on shelf-life and quality of onion genotypes was studied at CCS, Haryana Agricultural University, Hisar. The experiment was conducted in a single factor with one level with three replications. The lowest physiological weight losses % was recorded (7.19%) at 30 days and (14.81%) at 120 days in Hisar onion-4 and there was no seen sprouting up to 60 days in all the genotypes after storage and then after   start gradually sprouting in the bulbs in storage. lowest sprouting % was recorded from 90 days and 120 days (2.16% and 3.65%) in Hisar onion-4 respectively. Minimum rotting % was recorded in Hisar Onion-4 and Hisar Onion-7 and total minimum losses were recorded in Hisar Onion-4 and Hisar Onion-7 among the genotypes in storage. Minimum total losses was recorded in best check Hisar Onion-4 closely followed by genotype Hisar Onion-7 during storage.
Knowledge and Management of Buruli Ulcer Disease: A Case Study at Sekyere Afram Plains District of Ashanti Region, Ghana
Authors: Gyaase Philip , Lindsay Michael Kobina , Acheampong Emmanuel Boateng , Sampson David Ben
Published: May 2023

Introduction: The goal of the study was to assess the knowledge and management of Buruli ulcer disease in the Sekyere Afram Plains District of Ashanti Region.

Methods: The study used a quantitative study type and cross-sectional study design with a sample size of 251 comprising Buruli Ulcer (BU) patients, health workers and community members as study population. The study used a structured questionnaire for the primary data. The questionnaire was used because the respondents were literates and could read and respond to the items without difficulty. Data collected were edited and coded and statistically analyzed using Statistical Package for the Social Sciences (SPSS) version 26 software. Inferential and Descriptive statistics such as frequencies and percentages were used to describe the study variables. Chi-square (p-values) was used and the data were analyzed in Tables with significance level set at 0.05.

Results: The results revealed that the patient’s knowledge, about BU was 61.9% which was statistically significant (p-value= <0.001). It also revealed association between knowledge on Buruli ulcer and demographic characteristics of respondents (p-value =<0.001). Relatively colossal number of respondents (81.0%) revealed that they were not an active member of National Health Insurance Scheme (NHIS).

Conclusion: The study concludes that if health workers are trained on BU and more education is given to the community members on Buruli ulcer disease, their health seeking behaviour would be improved to reduce complications associated with Buruli ulcer disease in the District. The study recommends that Ghana Health Service (GHS) should organize training and refresher courses for health care workers to increase their knowledge on Buruli ulcer.
An Overview of COVID-19 and Its Progression in Ghana
Authors: Apenteng John Antwi , Korsah Samuel , Tagoe Miriam , Sarfo Anthony
Published: May 2023

This research focuses on the progression of the coronavirus pandemic in Ghana, measures put in place to fight the pandemic and evaluation of Ghana’s response in terms of both containing the pandemic and mitigating the social and economic effects of the COVID 19 pandemic.

Methods: The study mainly assessed the COVID-19 situation in Ghana within the period of March 2020 to MAY 2021. Data from reputable sources; Ministry of Health, Goggle scholar, Ghana Health Service, CDC, WHO, WTTC and online news articles were retrieved and assessed in quarterly basis. The results were further tabulated and graphically represented using Microsoft Excel application.

Results: A total of 94011 cases were recorded by the end of the of May 2021; first quarter of the second year. The highest number of active cases (11897), deaths (295) and critical cases (280) recorded were from December 2020 to February 2021. In the first quarter, the infection rate recorded was 3.77% which increased to 16.10% in the second quarter. However, with reinforcement of the COVID-19 protocol there was a significant decrease in infection rate in the final quarter for the studies; from March to May 2021 (3.60%).

Conclusion: Actions adopted by the Ghanaian government so far in handling the pandemic have generated significant achievements. It is however recommended that more control measures such as mass vaccination, mass testing and contact tracing will help track the infection and further reduce the rate of infection.
Decreased Mood Correlated with Decreased Exercise Adherence and Increased Pain
Authors: Hui Timothy , West Arielle , Gorham Jamin , Woldebirhan Yordanos , Subramanian Subu
Published: May 2023

Background: A home exercise program is an important part of recovery from musculoskeletal injuries and can improve pain, quality of life, and self-efficacy.  However, there are often challenges with patient adherence and measuring compliance. Mood and pain can have a positive and negative affect on a patient’s adherence and performance. Digital health, such as Recupe, provides an opportunity to examine the relationship between pain, mood, and exercise adherence outside the clinic.

Methods: A total of 864 subjects were retrospectively analyzed to assess mood and reps completed per session, mood and time spent exercising per session, and mood and pain level. Mood was measured using three categories: “Happy,” “Neutral,” and “Sad.” Pain was measured using the Numerical Pain Rating Scale (NPRS) of 0-10.

Results: The subject population included 331 males, 359 females, and 174 not stated. The average reps completed per session was 218.2 (130.0) for the “Happy” group, 163.3 (101.4) for the “Neutral” group, and 140.0 (95.7) for the “Sad” group with p-values <0.0001 between all groups.  The average time spent exercising per session were 29.54 minutes (24.63) for the “Happy” group, 21.80 minutes (18.30) for the “Neutral” group, and 22.31 minutes (21.23) for the “Sad” group with p-values <0.0001 between all groups. Lastly, the average pain level for each mood was 1.93 (1.69) for the “Happy” group, 4.4 (1.82) for the “Neutral” group, and 6.1 (2.00) for the “Sad” group with p-values <0.0001 between all groups.

Conclusion: There is a significant correlation between mood, reported pain levels, and adherence to the patients’ exercise programs. Patients who report higher pain levels, simultaneously report more depressed moods and demonstrate decreased exercise times and repetition counts. Yet, while this correlation is clear, the causation factor is not known and requires more research.  Clinicians should look to observe this pattern in patients to possibly improve recovery.
Histiocytic Necrotizing Lymphadenitis or Kikuchi–Fujimoto Disease: Clinical Experiences in North Africa
Authors: Selma M. Ben , Yahia W. Ben , Hassine I. Ben , Guiga A. , Abid M. , Anoun J. , Abdelkader A. Ben , Fredj F. Ben , Ghannouchi N. , Hachfi W.
Published: May 2023

Introduction: Kikuchi-Fujimoto disease or Kikuchi disease (KD) or histiocytic necrotizing lymphadenitis is an uncommon disease more frequent in Asia. It is diagnosed with lymph node histopathological findings.

Objective: To perform a systematic review of Kikuchi’s disease (KD) cases and describe clinical manifestations and associated etiology in the Tunisian population.

Methods: We conducted a multicentric descriptive study collecting patients with histologically proven KD. Clinical data, laboratory results, histopathologic examination, associated pathologies, and patient evolution were included.

Results: The search included 9 patients. They were 7 women and 2 males with a median age of 45 years old [24-72]. Common clinical manifestations were fever (n=8) and arthralgia (n=7). Lymph nodes mainly were bilateral (n=8), multiple (n=9), and in the cervical region (n=8) and axillary area (n=6). Laboratory results showed inflammatory syndrome and elevated lactate dehydrogenase. Areas of necrosis, karyorrhectic debris, and accumulation of histiocytes were specific histologic findings noted for all patients. Systemic Lupus Erythematosus was associated with KD in 2 patients and with Sjögren disease in one of them. Other associated pathologies were Lymphohistiocytic activation syndrome, lymphocytic meningitis, sepsis from a urinary tract infection, and idiopathic interstitial lung disease. Corticosteroids were prescribed in 4 cases. The other 5 cases had spontaneous regression of symptoms. The outcomes were favorable with recovery in 3 cases. Five patients developed Hodgkin lymphoma, myelodysplastic syndrome, and lupus nephropathy after KD diagnosis.

Conclusions: KD is exceptional in North Africa. The study noted the same clinical and histological findings in the literature. SLE was the most associated pathology. No ethnic variability was detected.
Design and Implementation of an IOT Based Smart Home Monitoring and Control System Using NodeMCU
Authors: Aminu Muhammad , Yerima Ali , Salisu Abubakar , Adamu Abbas
Published: May 2023

This paper presents the design and implementation of an IoT-based smart home monitoring and control system using a NodeMCU firmware and prototyping board. The system allows the user to remotely control electrical appliances through a web-based user interface dashboard. The system uses sensors DHT11 to monitor the temperature and humidity of the home and MQ 2 to monitor the air quality and alerts the user in case smoke or fire is detected. Various HTML scripts are executed to develop a web-based dashboard interface where the user interacts with the system. When connected to the internet, the system generates an IP address that is used to assess the web page for monitoring and control of various house appliances. A maximum coverage range of up to 42.05 meters indoors was achieved by the system using the onboard Wi-Fi module on the NodeMCU. In addition, a correlation was observed between the Wi-Fi coverage distance and the response time to a command signal from the web-based dashboard. The system provides energy efficiency, home security, and centralized remote control of appliances thereby minimizing human efforts and energy losses and providing a friendly and secure home.
Space Based Assessment of Base Transceiver Stations in Kwamba, Niger State, Nigeria
Authors: Sedwaa F. N. , Iwu O. , Ihenacho N. M. , Aderoju O. M.
Published: May 2023

Global System for Mobile Communications (GSM) started operations in Nigeria on the 16th of May, 2001. An important feature of the communication system is the Base Transceiver Stations (BTS). However, their installations have brought about public concerns and fears, specifically to issues relating to environmental risk, public health and sometimes construction problems that might result to mast collapse. This study is aimed at identifying the spatial distribution of BTS in Kwamba, analysing the terrain of the study area and examining their level of compliance to NESREA standards for siting a BTS. The data for the Kwamba study was collected from two sources; Primary and Secondary sources. The primary data include the use of GPS to obtain coordinates of the GSM base stations and their respective elevations. The Secondary and geographic data includes Google Earth imagery obtained from Google Earth, Landsat images, SRTM data from USGS Earth Explorer and shape files (roads etc) from OSM data. ArcMap was used to plot a map showing the distribution and slope extraction of the study area to provide information on the terrain. Also, using NESREA stated standard, 10metre buffer test on all existing BTS in Kwamba was carried out using ArcMap. Findings from the research revealed that there are 24 BTS distributed randomly in Kwamba. 7 out of the 24 failed the 10metre buffer test, meaning they were not in compliance with 10m setback distance as stated by NESREA for locating a BTS close to residential homes. The study recommends that stakeholder(s) imbibe the use of GIS techniques in the siting of BTS as it will assist in monitoring of non-compliance to the regulated standard of NESREA by the service providers. The adaptation of use of GIS techniques will also assist the regulatory bodies in effectively carrying out constant supervision of the service providers.
Biochemical Constituents and Anticancer Activities of the Essential Oils of Lannea egregia Engl. & K. Krause
Authors: Ayodele Oluwatosin T. , Olaoluwa Olaoluwa O. , Aiyelaagbe Olapeju O. , Guido Flamini , Ogbole Omonike O. , Akinleye Toluwanimi E. , Adeniji Adekunle J.
Published: May 2023

Introduction: The Increase in cancer deaths has raised concerns among scientists to research on prospective anticancer agents. Lannea egregia was selected for this research because it has been identified to have ethnobotanical claims in relation to the cure of cancer in South-West Nigeria.

Aims: To analyze the chemical constituents and determine the anticancer properties of the essential oils obtained from Lannea egregia Engl. & K. Krause Leaf, twig and stem-bark.

Study Design: This study was designed to assay the chemical constituents of Lannea egregia and based on the ethnobotanical claims, the anticancer activities of this plant was studied.

Place and Duration of Study: Department of Chemistry, Dipartmento di Farmacia, Via Bonanno 6, Universita di Pisa and University of Ibadan and Department of Virology, University of Ibadan, Ibadan, Nigeria. July 2018- April 2021.

Methodology: Essential oils (EOs) from leaf, twig and stem-bark of Lannea egregia were extracted by hydro-distillation. Chemical compositions were characterized using Gas Chromatography–Mass Spectrometry (GC–MS). Cytotoxicity screenings of EOs were determined on human rhabdomyosarcoma (RD) and breast adenocarcinoma (MCF-7), using MTT [3-(4,5 dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide] cell viability assay.

Results: Leaf, twig and stem-bark EOs gave good yields of 0.12%, 0.43% and 0.33%, respectively.

Fifty-five, thirty-three and thirty-eight compounds were identified in leaf, twig and stem-bark EOs, accounting for 99.1%, 97.8% and 95.8% of them. Most abundant compound in leaf, stem-bark and twig EOs was β-caryophellene (28.2, 23.4 and 13.2%, respectively).

Leaf EO displayed strong cytotoxicity against RD and MCF-7, with 50% cytotoxicity (CC50) of 1.69 and 15.81µg/ml, respectively. Twig EO exhibited good selectivity with selectivity index of 24.8 and 10.8 for RD and MCF-7, respectively.

Conclusion: Results showed that EOs have good anticancer properties.
Linagliptin in Combination with Emblica officinalis Gaertn Improves Glycemic Control through Alleviating Dyslipidemia and Oxidative Stress on Streptozotocin Induced Diabetic Rats
Authors: Khanam Khadiza , Rajia Sultana , Kamal A. H. M. Mostofa , Jahan Md. Sarwar , Rahman Md. Aziz Abdur , Alam A. H. M. Khurshid , Rashid Mamunur
Published: May 2023

Objectives: Diabetes is a complex chronic metabolic disorder. Today, many diabetes patients are known to supplement their standard therapies with herbal medications that have antidiabetic characteristics. The purpose of the study was to examine the fixed dose combination of linagliptin and Emblica officinalis Gaertn (aq FE) for its hypoglycemic, hypolipidemic, and antioxidant properties.

Methods: Streptozotocin (45 mg/kg b.w.) was administered intraperitoneally to Wister albino rats to cause diabetes. Linagliptin (5 mg/ 70kg b.w), aqueous fruit extract of Emblica officinalis Gaertn (200 mg/kg b.w.) and fixed dose combination therapy of linagliptin (2.5 mg /70kg b.w) with aqueous fruit extract of Emblica officinalis Gaertn (100 mg/kg b.w) were administered orally once daily for four weeks.   After that fasting blood glucose level (FBG), low density lipoprotein (LDL), high density lipoprotein (HDL), total cholesterol (TC) and triglycerides (TG) were measured in serum with streptozotocin (STZ)-induced diabetes. Typical procedures were used to measure the antioxidant activity by the estimation of catalase (CAT) and superoxide dismutase (SOD) activity.

Results: The combination therapy significantly (p<0.05) reduced the FBG, TC, TG, LDL level in compared to the diabetic control group (p<0.05). Significant (p<0.05) increased of HDL was also observed. The antioxidant activity significantly increased after the administration of fixed dose combination therapy in compared to diabetic control group. These alterations were vastly superior to those of linagliptin with Emblica officinalis Gaertn (aqFE) monotherapy.

Conclusion: This study suggests that the fixed dose combination therapy of linagliptin and Emblica officinalis Gaertn (aq FE) might be potent on antihyperglycemic antidyslipidemic and antioxidative effect.
The Crucial Role of Microbiological Testing in Ensuring Safety and Efficacy of Medical Devices: An Overview
Authors: Sharma Akash , Sharma Nishant , Luthra Gaurav
Published: May 2023

Microbiological testing is a critical aspect of the development and evaluation of medical devices, as it plays a vital role in ensuring their safety and efficacy. This article highlights the importance of microbiological testing in medical device development and the various types of tests that are commonly performed. Microbiological testing is essential for assessing the potential risks associated with medical devices, such as bacterial contamination or infections. Testing can also help to identify potential sources of contamination during the manufacturing process and to monitor the efficacy of sterilization methods. In addition, microbiological testing is crucial in determining the appropriate usage and maintenance procedures for medical devices. By providing accurate and reliable data, microbiological testing can aid in the development of safe and effective medical devices, while also ensuring compliance with regulatory standards. Overall, this article emphasizes the critical role of microbiological testing in the development and evaluation of medical devices, and highlights its significance in maintaining patient safety and improving health care outcomes.
Implementing a Risk-Based Approach to Quality Management System ISO-13485 Processes in Compliance with EUMDR 2017/745 for Medical Device Industry
Authors: Sharma Akash , Luthra Gaurav
Published: May 2023

The European Union Medical Device Regulation (EUMDR 2017/745) requires medical device manufacturers to implement a risk-based approach to quality management system (ISO13485) processes. This article provides an overview of the importance of QMS processes in the medical device industry and explains the need to implement a risk-based approach to comply with EUMDR. Implementing a Risk-Based Approach to Quality Management System ISO-13485 Processes in Compliance with EUMDR 2017/745 for Medical Device Industry discusses the steps involved in implementing a risk-based approach to QMS processes, including identifying potential risks, evaluating and prioritizing risks, developing and implementing risk mitigation strategies, and monitoring and continuously improving QMS processes. Additionally, the article highlights the benefits of adopting a risk-based approach, such as improved product safety and efficacy, enhanced regulatory compliance, improved customer satisfaction, and cost savings. It also addresses the challenges in implementing a risk-based approach, including a lack of resources and expertise, resistance to change, and limited understanding of risk management principles. Overall, this article emphasizes the importance of a risk-based approach to QMS processes in the medical device industry to ensure the safety and effectiveness of medical devices and comply with regulatory requirements.
Eosinophilic Oesophagitis in Patients Presenting with Dysphagia: A Retrospective Study from a Single Tertiary Care Centre in Saudi Arabia
Authors: Jawa Hani A. , Bahurmuz Razan Abdulhakim , Bokhari Raneem Abdullah , Alhazmi Duaa Jamil , Saeed Afnan Bakur , Halawani Lamis Khalid , Mosli Mahmoud Hisham , Qari Yousef A. , Bokhary Rana Y. , Alfawaz Mohammed
Published: May 2023

Background and Study Aims: Eosinophilic oesophagitis (EoE) is an increasingly common cause of dysphagia in many Western countries, especially in young adults; however, the prevalence of EoE in Middle Eastern countries remains unknown. We aimed to estimate the prevalence of EoE in Saudi patients presenting with dysphagia. Additionally, we aimed to assess the practice pattern of physicians with respect to evaluating these patients.

Patients and Methods: We performed aretrospective review of all adolescent and adult patients who underwent upper gastrointestinal endoscopy for the assessment of dysphagia. Demographic data and endoscopic and histologic findings were reviewed. The primary outcome was the prevalence of biopsy proven EoE, defined as 15 or more eosinophils per high power field (≥15eos/hpf) in patients presenting with dysphagia. Secondary outcomes included the frequency of endoscopic features suggestive of EoE and the physician’s judgement about the need for oesophageal biopsies to diagnose EoE.

Results: A total of138 patients were identified and reviewed. The mean age was 50.7 years; 43.5% were males and 56.5% were female. Endoscopy revealed normal oesophageal mucosa in 52.9% of the patients. White plaques were reported in 4.3%, linear furrows in 2.9% and multiple rings (trachealization) in 2.2% of patients. Oesophageal biopsies were obtained from 20.3% of all patients to rule out EoE, this included 7.1% of those with normal appearance of the oesophageal mucosa. Only two patients (1.4%) with biopsy proven EoE were identified from this cohort; both were young adults.

Conclusions: Failure to perform oesophageal biopsies in patients presenting with dysphagia as per international guidelines could explainthe low prevalence of EoE observed in this population. Alternatively, the prevalence of EoE may be lower than expected in the Middle Eastern countries. Large prospective studies are necessary to accurately assess the prevalence of EoE in Middle Eastern countries.
The Blooming Flowers of Tea Plants and Their Honey
Authors: Saito Kieko , Nakamura Yoriyuki
Published: May 2023

Tea (Camellia sinensis L.) leaves provide beneficial effects for human health, and the functions of the main components of their leaves have been widely studied. Recently several physiological functions of tea flowers have been reported, and the flowers have received attention as a natural healthy material for food and cosmetics. It is not well known that the fragrant tea flowers have sweet nectar. The tea nectar may be attractive to honeybees. However, the honey from tea flowers has not been studied, even though in autumn, many tea fields are filled with blooming flowers in almost all the tea production areas around the world. In addition, honey from tea flowers has not been seen on the market. It was unclear whether tea honey is available. The study used honeybees (Apis mellifera L.) and took a small amount of honey from the blooming flowers of tea plants, which contained theanine (L-glutamic acid γ-ethylamide), a specific amino acid of tea plants. The theanine concentration of the nectar of the tea flowers exceeded that of the honey. Theanine is an extremely rare amino acid in nature, and it has psychoactive properties. This result is evidence that this honey is derived from tea flowers. Furthermore, the concentration of caffeine in the tea nectar might affect the honeybee’s brain to improve memory, suggesting that honeybees prefer to collect the nectar and produce honey. This study aims to prove that tea flower honey can be harvested and further proposes a unique tea sightseeing where visitors can taste the honey of tea flowers in the gorgeous scenery and fragrance of flower tea gardens.
Peste Des Petits Ruminants: An Update
Authors: Tenuche O. Z. , Emikpe B. O. , Godwin E. , Enem S. I. , Egwu G. O.
Published: May 2023

Peste des petits ruminants (PPR) is a notifiable and reportable disease recognised by the Office Internationale Epizooties (OIE) and penned for eradication by 2030. It is an endemic and devastating disease of small ruminants in some countries of Africa, Asia, and the Middle East. The disease militates against small ruminant production and increased flock numbers in the region.  Information and literature on the current review was especially obtained and compiled from CABI abstract data base, PubMed, Scopus, Elibrary USA and other online publications. This review highlights the viral structure, epidemiology, predisposing factors, clinical signs, pathology, immunoprophylaxis, diagnostic techniques and therapeutics of the disease with a view to generating increased scientific research interests on PPR. It is hoped that more robust scientific research breakthroughs could emerge particularly in the area of immunoprophylaxis, rapid penside diagnosis, and alternative therapeutics such as the use of probiotics. This will in no small measure boost small ruminant production, alleviate poverty and increase food security in countries endemic with the disease.
The Trade-Off between Strategic Orientation Options to Achieving Sustainable Tourism Development - An Analytical Study on a Sample of Workers in First-Class Hotels in Baghdad Governorate
Authors: alabachee Ali sahib flayyih
Published: May 2023

The current research seeks to know the nature of the relationship between strategic orientation (STO) and sustainable tourism development (SUSTD) Among a sample of employees in upscale hotels in the Baghdad region, as its importance is represented in addressing two very important variables in the regulatory environment, as well as laying the correct and appropriate foundations To address a real problem that directly affects the work environment in one of the most important Iraqi organizations, so the researchers used the random sample method and distributed (360) questionnaires to some male and female employees in the aforementioned organization. The number of questionnaires retrieved was (242), and those valid for statistical analysis were (232) with a response rate of (93%) of the retrieved questionnaires, and they were analyzed by the advanced statistical program (SPSS.26), as well as the statistical program (AMOS.24).). Theoretical results showed that there is a knowledge gap several staff in first-class hotels in the Baghdad city located in particular were studied to understand the relationship between strategic orientation (STO) and sustainable tourism development (SUSTD) in organizations in general. The results of the study show a favorable and significant relationship between organizational strategic orientation and SUSTD. (STO) and Sustainable Tourism Development (SUSTD), as the proactive orientation is commensurate with the environment of the hotels under study in achieving sustainable tourism development through development and creativity in the field of services provided to current and potential customers, and constantly searching for new opportunities associated with the current marketing operations, to continue searching for new markets.