bluuebunny/crossref_metadata_2025 huggingface dataset:
Diagnóstico da relação de gênero no IFPB com enfoque no Curso Técnico em Edificações
Authors: Andrade Kecia Nóbrega , Severo Ana Luíza Félix
Published: September 2021

A classe feminina vem tomando cada vez mais consciência sobre seus direitos sociais e ideias estigmatizadas nas mais diversas culturas que segregam os papéis masculino e feminino. Seguindo essa linha de raciocínio e instigada pela necessidade de entender o problema das relações misóginas que circundam a formação em Edificações no universo feminino, assim como o preconceito velado que está presente no dia a dia, por intermédio de dados, busca-se identificar se o IFPB – Campus Patos está nessa realidade. A pesquisa está dividida em duas etapas: estudo de gênero nos projetos de pesquisa e extensão do campus e levantamento de dados sobre o tema, para o Trabalho de Conclusão de Curso (TCC). Direcionada a entender gênero na Educação no Campus Patos, sobretudo no Curso Técnico em Edificações, a pesquisa mostra como essa relação social muda ao longo dos anos. Deste modo, proporciona-se um diagnóstico do Curso de Edificações do Campus Patos.
Efeito da incorporação de nanosílica e sílica ativa em argamassas frente ao ataque interno e externo de sulfatos
Authors: Schmalz Rosana , Alves Raphael Klein , Leoni Vitor Lourensato , Quarcioni Valdecir Ângelo , Ferreira Fernanda Giannotti da Silva
Published: September 2021

A preocupação com a durabilidade das estruturas de concreto cresce cada vez mais e, para que a vida útil das construções seja alcançada, as características do local onde a edificação será construída devem ser consideradas desde as etapas iniciais de projeto. Um dos agentes agressivos mais prejudiciais ao concreto é o íon sulfato, que pode estar presente no solo, na água do mar ou em águas subterrâneas. Este trabalho avaliou os efeitos que a incorporação de nanosílica e sílica ativa ocasionam em argamassas frente ao ataque de sulfatos de origem interna e externa. Para isso, foram desenvolvidas quatro argamassas com diferentes teores de adições e foram realizados os ensaios de variação dimensional, perda de massa e resistência à compressão. Os resultados obtidos indicam que as adições reduziram o ganho de massa dos concretos, sendo observada perda de resistência à compressão após 91 dias de ataque interno. Uma menor perda de resistência mecânica foi verificada na argamassa contendo 10% de adição de nanosílica.
Adição conjunta do resíduo de cerâmica vermelha e da cinza do bagaço da cana-de-açúcar na produção de tijolos ecológicos
Authors: Duarte João Batista , Ramos Filho Ricardo Eugênio Barbosa , Fonsêca Nayara Jhéssica Marques da , Dias Leonardo Nascimento , Silva Vamberto Monteiro da , Acchar Wilson
Published: September 2021

As indústrias da construção civil e do agronegócio buscam processos e produtos que necessitem de uma menor quantidade de energia na sua fabricação. Diversos resíduos oriundos dos segmentos citados são aproveitados como fundentes, ligantes, aditivos, etc. evitando o descarte in natura. A cinza do bagaço da cana-de-açúcar (CBC) e o resíduo de cerâmica vermelha (RCV) são passivos que, isoladamente, apresentam potencial pozolânico. Quando misturados, poderão gerar novos silicatos e aluminatos de cálcio hidratados, decorrentes da recombinação da sílica e alumina amorfas existentes em sua composição com a fase Portlandita, advinda da hidratação do cimento e da constituição química da cal hidratada. A pesquisa avaliou a viabilidade do uso combinado desses resíduos como aditivo pozolânico na moldagem de tijolos maciços de solo-aglomerante(s), sem e com teores de 2% e 4% de RCV e 2% de CBC. Foi realizada a caracterização física, química e mineralógica dos insumos e, em seguida, a moldagem dos tijolos. Amostras dos melhores resultados foram submetidas aos ensaios de DRX e MEV. As composições S12C4RCV e S12C2CBC2RCV, em relação às propriedades físicas e mecânicas, atingiram os melhores resultados.
Antioxidantes naturais aplicados em produtos à base de carne bovina: uma alternativa promissora
Authors: Rosa Luana Carolina Martins , Pintro Paula Toshimi Matumoto
Published: September 2021

A carne é um dos alimentos mais consumidos na dieta humana por ser rica em nutrientes. Sua composição e as etapas de processamento fazem com que se torne mais suscetível ao processo de oxidação e, consequentemente, a uma diminuição da qualidade, por provocar mudanças nas características sensoriais da carne e de seus derivados. Isso afeta a aceitabilidade por parte do consumidor e também traz riscos à saúde humana, pois a formação e o consumo dos radicais livres causam danos ao organismo. Com isso, a adição de antioxidante é uma prática realizada pela indústria de alimentos, com a finalidade de preservar o produto e estender seu tempo de prateleira; no entanto, os antioxidantes sintéticos comumente utilizados são considerados tóxicos. Atualmente as pesquisas vêm buscando alternativas naturais para a substituição desses aditivos. Dessa forma, esta revisão tem por objetivo mostrar alternativas naturais com alto potencial antioxidante que podem ser aplicadas em produtos cárneos e em embalagens ativas desses produtos.
Avaliação do isolamento acústico de protótipo revestido com argamassa adicionada de EVA e vermiculita conforme critérios da NBR 15575-4
Authors: Menezes Francisco Ygor Moreira , Souza Sara Jamille Marques de , Silva Cícero Joelson Vieira
Published: September 2021

A preferência por determinados tipos de materiais e a tecnologia construtiva implicam em circunstâncias que podem agregar características de forma a aprimorar as condições de conforto sonoro de edificações, além de influenciar nas mais variadas propriedades que se tem em um sistema construtivo. Desta forma, este trabalho tem por objetivo realizar uma análise, segundo critérios da NBR 15575-4 (ABNT, 2013), Edificações Habitacionais – Desempenho, Parte 4: Sistemas de vedações verticais internas e externas (SVVIE), do conforto acústico de um Sistema de Vedação Vertical (SVV) composto por argamassa de revestimento acrescida da junção entre Etileno Acetato de Vinila (EVA) e vermiculita, com 1,25% em relação à massa da areia, e traço de 1:1:6. Tratou-se de um trabalho experimental no qual, do ponto de vista metodológico, com base na NBR ISO 10052 (ABNT, 2020), Acústica — Medições em campo de isolamento a ruído aéreo e de impacto e de sons de equipamentos prediais (Método simplificado), realizou-se testes para avaliação do isolamento acústico e, em seguida, recorreu-se a NBR 15575-4 (ABNT, 2013) para classificação e avaliação do conforto acústico. Em conformidade com os métodos utilizados obteve-se, como principais resultados a classificação do isolamento acústico no protótipo como de nível superior, com D2m,nT,w de 32 dB.  
Planejamento: da racionalidade hierárquica à dimensão intuitiva e democrática
Authors: Lira Ana Cláudia De Queiroz , Cavalcanti Vladyr Yuri Soares de Lima , Gomes Maria de Lourdes Barreto
Published: September 2021

O propósito deste ensaio é refletir sobre a evolução do planejamento estratégico enquanto instrumento de gestão que influencia a direção, escala e velocidade de transformações institucionais considerando os cenários de mudanças e incertezas nos campos social, político e econômico, dentro de uma lógica mais competitiva, em instituições empresariais e governamentais. Trata-se de um ensaio teórico, operacionalizado a partir de revisão de literatura sobre a atividade de planejamento, considerando a análise em quatro dimensões: Dimensão 1: visão tradicional do planejamento no âmbito empresarial; Dimensão 2: visão do planejamento incorporada ao contexto de pensamento estratégico; Dimensão 3: visão do planejamento no âmbito governamental em uma perspectiva econômico-orçamentária; Dimensão 4: visão do planejamento no âmbito governamental em uma perspectiva situacional. No limiar da bibliografia apresentada neste ensaio, é possível entender que o processo de planejamento nos âmbitos empresarial e governamental deve ultrapassar os limites de racionalidade, burocracia e prescrição e seguir dentro de uma lógica gerencial focada nos aspectos subjetivos da dimensão intuitiva, flexibilidade no curto prazo, com consistência no longo prazo, criatividade, inovação, construção da capacidade de aprendizagem, de forma a estabelecer uma atribuição mais eficiente da ação de planejamento em um contexto de pensamento estratégico global. 
Mobilidade e caminhabilidade em foco: estudo de remodelação viária no bairro central de Brejo Santo-CE a partir do conceito de Ruas Completas
Authors: Ricarte Nathaniele Alves , Jeronymo Caroline Muñoz Cevada
Published: September 2021

O principal objetivo deste artigo foi realizar um estudo de remodelação no bairro central de Brejo Santo-CE aplicando o conceito de Ruas Completas. Para o desenvolvimento da pesquisa, focaram-se três etapas metodológicas: revisão da literatura, diagnóstico local do trecho da rua estudada e desenvolvimento do estudo de implantação. A partir da revisão bibliográfica foi possível compreender que as Ruas Completas são uma forma de redistribuir o uso do solo, pois redesenham as vias para que todos os modais de transporte consigam transitar de forma harmoniosa, priorizando o pedestre e incentivando a mobilidade ativa. No desenvolvimento do diagnóstico local observou-se que as vias estudadas não possuem estruturas adequadas para contemplar pedestres e ciclistas e priorizam apenas o transporte motorizado. O estudo de implantação contemplou estudo de arborização, iluminação pública, reordenamento de calçadas, pistas de rolamento e estacionamentos e distribuiu os espaços de forma mais democrática, incentivando a acessibilidade para todas as pessoas, o pedestrianismo, o ciclismo e a diversidade do solo. Concluiu-se que existem diferentes formas de estimular a mobilidade ativa em conformidade com as Ruas Completas, atendendo a demanda local. Considera-se que este trabalho colabora para ressaltar pontos que precisam ser considerados ao planejar vias urbanas e para demonstrar a importância das Ruas Completas ao compará-las com as ruas urbanas tradicionais.
The Macroeconomic Determinants and FDI: Evidence from 14 International Alliances
Authors: Paul Sujan Chandra , Rosid Md Harun Or , Islam Mohammad Rakibul , Ferdous Refat
Published: September 2021

This study investigates the relationship between Foreign Direct Investment (FDI) and some macroeconomic variables such as Gross Domestic Product (GDP), Gross Capital Formation (GCF), Agriculture, Forestry, and Fishing (AFF), Industry, Import, Export, Inflation and Unemployment rate. Panel Data of 14 regional alliances countries from 1990-2018 were collected from The World Bank website. Robust regression models are used in this study. This research found that GDP had significant positive relationship with FDI in all regions except Arab League, EU and G7 countries. GCF had significant positive relationship with FDI in Arab League, BRI, GATT, NAFTA countries & negative relationship in APEC, G7 countries. AFF had significant positive relationship with FDI in BRICS, GATT countries & negative relationship in African Union, ASEAN, BIMSTEC, BRI, BRICS, SAFTA countries. Industry had significant positive relationship with FDI in African Union, BRI, NAFTA, OECD countries and negative relationship in BRICS, G7, G20 countries. Import had significant positive relationship with FDI in African Union, APEC, Arab League, ASIAN, BRI, G7, G20, GATT countries and negative relationship in BRICS countries. Export had significant positive relationship with FDI in BRICS countries and negative relationship in African Union, ASEAN, BRI, G20, GATT, OECD, SAFTA countries. Inflation had significant positive relationship with FDI in GATT, SAFTA countries and negative relationship in African Union, APEC countries. Unemployment rate had significant positive relationship with FDI in African Union, BRI, BRICS, EU, G20, GATT, OECD, SAFTA countries and negative relationship in ASEAN countries.
Marginal Effects of Factors Influencing Procurement Records Management: A Survey of Selected Procuring Entities in Tanzania
Authors: Mohamed Bakari Maligwa , Rasheli Geraldine Arbogast , Mwagike Leonada Rafael
Published: September 2021

This paper estimated marginal effects on dependent variable against independent variables on the management of procurement records in the Tanzania procuring entities (PEs). The study was a survey of selected PEs. Data were collected through structured questionnaires. Sample was arbitrarily set at 200 PEs whereby questionnaires were randomly administered to 200 respondents within 200 PEs found in Dar es Salaam, Dodoma, Morogoro, Pwani, and Tanga. At the end of questionnaires administration the response rates were 83.1% PEs and 75% respondents respectively. Based on the results and findings, marginal effects were identified, established and estimated. The study was concluded that: PEs having no equipment and facilities for keeping records are 2.7% less likely to have proper management of procurement records, PEs with limited equipment and facilities for keeping records are 4.1% less likely to have proper management of procurement records, and PEs with no security and safety measures in managing records are 1.4% less likely to have proper management of procurement records, ceteris paribus. On the contrary, procurement records managed by personnel who are knowledgeable and skilled are 1.3% more likely to be properly managed, procurement records that are managed by competent personnel and who have the on-the-job training on records management are 1.0% more likely to be properly managed, PEs with available storage space for keeping records, improves management of procurement records by 4.8%, PEs with adequate storage space for keeping all kinds of procurement records, improves management of procurement records by 6.5%, and PEs that have sufficient security and safety measures in managing procurement records, improves management of procurement records by 4.3% ceteris paribus.
Policy Development of the Child-Friendly City: Case Study of South Tangerang City Regional Government
Authors: Satispi Evi
Published: September 2021

This study aims to find out the Policy Development of the City of South Tangerang to implement the Ministerial Regulation of the Women's Empowerment and Child Protection of the Republic of Indonesia Number 11 of 2011, regarding the Child-Friendly City Development Policy using a qualitative approach and descriptive research methods. That is to explain phenomena in depth through data collection. This type of research provides an overview, an accurate explanation objectively about the actual state of the object under study. Research design uses the theory of public policy making according to Metter and Horn. The results of the South Tangerang development research generally went well. Among them; achievement of basic health and welfare, the large number of breastfeeding facilities and breastfeeding corners, high percentage of complete basic immunizations for children, low prevalence of malnutrition in children under five, low infant mortality rate (IMR), as well as active and outstanding ARHCIC (Adolescent Reproductive Health Counseling Information Center).
Trichomonas Vaginalis Infection in Men with High-Risk Sexual Behaviors
Authors: Dalimi Abdolhossein , Payameni Samira
Published: September 2021

Background: Trichomonas vaginalis is a protozoan pathogen of the human genitourinary tract, which is the cause of trichomoniasis. The disease is one of the most important non-viral sexually transmitted infections in the world. Many studies have been performed on the molecular identification of Trichomonas in men in different parts of the world, but in Iran, such a study has been very limited. We aimed to detect T. vaginalis in urine of men with unusual sexual behavior by wet mount microscopic observation, culturing in TYM-33 and molecular method in Tehran, Iran.
Methods: Totally, 47 urine samples were collected from men with high-risk sexual behaviors referred to Health Care Centers in South of Tehran, Iran during 2017-2018. After urine centrifugation and wet mount sediment preparation, the samples were cultured in TYM-33 medium and examined microscopically. Then DNA was extracted from urine sediment samples and finally the 18srRNA gene was amplified by PCR.
Results: Thirty-one (65.95%) urine samples were positive for T. vaginalis by PCR. Of these, only 6 (12.76%) were detected positive by wet mount method and 25 (53.19%) by culture and successive passages. 
Conclusion: The high prevalence of trichomoniasis among men with high-risk sexual behavior in Tehran indicates a potent health risk condition for families. Of course, this percentage is not the real infection rate in ordinary men in Tehran. This situation could be controlled by promoting concurrent diagnosis and treatment of T. vaginalis infection in men and women, as well as strengthening religious beliefs and health education in the individuals.
Co Expression of GMFβ, IL33, CCL2 and SDF1 Genes in the Acute Stage of Toxoplasmosis in Mice Model and Relation for Neuronal Impairment
Authors: Najafi Mehri , Amini Razieh , Maghsood Amir Hossein , Fallah Mohammad , Foroughi-Parvar Faeze
Published: September 2021

Background: Toxoplasma gondii is an obligate intracellular parasite that migrates through macrophages or dendritic cells to neurons and nerve cells. Glia Maturation Factor (GMF) is a pre-inflammatory protein that is expressed in the central nervous system (CNS). GMFβ expression is related to IL33 and CCL2 and SDF1 in some neurodegenerative diseases. According to the importance of GMFβ in neurodegenerative diseases and its association with IL33, CCL2 and SDF1 genes, this study was designed to determine the level of expression of these genes in the brains of mice with acute toxoplasmosis.
Methods: Tachyzoites of T. gondii RH strains were injected to 5 Swiss Albino mice. At the same time, healthy mice were inoculated with the Phosphate-buffered saline (PBS). Their brains were removed and kept at -70 oC in order to RNA extraction, cDNA syntheses and Real Time PCR performance. The level of gene expression was investigated with SYBR Green Quantitative Real-Time PCR.
Results: GMFβ gene expression increased significantly (P=0.003) 3.26 fold in Toxoplasma infected mice in comparison to the control. GMFβ gene expression was associated with increased expression level of IL33, CCL2, and SDF1 genes.
Conclusion: Considering the prominent role of GMFβ in CNS as well as the immune system, the elevation of GMFβ, IL33, CCL2 and SDF1 genes expression in the early stage of toxoplasmosis is associated with the occurrence of neuropathological alterations. Detection of these genes as an indication of brain damage in the early stages of Toxoplasma infection can prevent neurodegenerative disorders following acquired toxoplasmosis.
Molecular Identification of Neospora caninum Infection in Abort-ed Fetuses of Sheep, Cattle, and Goats in Mazandaran Province, Northern Iran
Authors: Salehi Behnaz , Amouei Afsaneh , Dodangeh Samira , Daryani Ahmad , Sarvi Shahabeddin , Safari-Kharyeki Mohammad Reza , Salehi Saeid , Hosseini Seyed Abdollah , Hosseininejad Zahra
Published: September 2021

Background: We aimed to identify Neospora caninum DNA in the brain samples of aborted fetuses of cattle, goats, and sheep in Mazandaran, northern Iran, using PCR.
Methods: In total, 133 aborted fetuses (51 sheep, 78 cattle, and 4 goats) were randomly collected from different stages of gestation in various regions of Mazandaran, Iran, from Mar 2016 to May 2017. The DNA was extracted from all the brain samples using phenol chloroform isoamyl alcohol instructions. The Nc-5 gene was used for the detection of N. caninum DNA by nested-PCR assay.
Results: The detection of N. caninum DNA was confirmed by the observation of a 227 bp band in 24 samples of 133 aborted fetuses (18.1%). The highest prevalence rate of N. caninum was detected in the cattle (20.5%) followed by the sheep (15.6%); however, no positive cases were reported in the goats. The highest and lowest prevalence rates of the infection were reported as 23.8% and 8.6% in Qaemshahr, and Behshahr, respectively. The prevalence rate of infection (32%) in the early gestational period was higher than those in the middle (15%) and late (3.8%) gestational periods.
Conclusion: The obtained data of the present study indicated that N. caninum infection may partly be responsible for abortion and economic loss in livestock farming in Mazandaran Province.
The Comparison of the IFN-ɤ, TNF-α and IL-10 Cytokines in Healing and Non-healing Cutaneous Leishmaniasis
Authors: Taraghian Mina , Hanif Helena , Mousavi Parisa , Baharlooeyan Cheshmeh Zahra , Samei Azam , Abdollahi Abbas , Vazini Hossein
Published: September 2021

Background: Leishmaniasis is one of the main vectors borne and neglected tropical parasitic diseases. T cell cytokine responses are highly important in the presentations of disease such as control or progression, and understanding of the host immunological response is valuable in diagnosis, follow-up, and vaccine designs. In the current study, the profile of IFN-ɤ, TNF-α, and IL-10 cytokines was investigated through the ELISA technique in PBMCs isolated from antimony resistance and susceptible patients.
Methods: In this experimental study, 54 patients with healing (n=27) or non-healing (n=27) CL were recruited. Lesion samples were collected to determine the genotype of Leishmania spp. and peripheral blood mononuclear cells (PBMCs) were obtained to evaluate the cytokines profiles using soluble Leishmania antigen (SLA) and phytohaemagglutinin (PHA) mitogen. Cytokines were assessed by the ELISA technique
Results: The IFN-ɤ and TNF-α cytokines were significantly increased in the healing group treated with both SLA antigen and PHA mitogen (P<0.001). The level of IL-10 was significantly increased in non-healing and significantly declined in healing groups (P<0.001).
Conclusion: The profile of IFN-ɤ, TNF-α, and IL-10 cytokines are crucially associated with the response of treatment.
First Report of Passerilepis parina (Cestoda: Hymenolepididae) from Parus major in Iran: A Probable Fatal Case Due to Hyperin-fection
Authors: Mohtasebi Sina , Teimouri Aref , Abbaszadeh Afshar Mohammad Javad , Abbasian Hamed , Mobedi Iraj , Allahmoradi Mahya , Mowlavi Gholamreza
Published: September 2021

Cestodes are important parasites that can affect the health of humans and wildlife. Among these, the genus Passerilepis is an important endoparasite of Passeriform birds while poorly studied in Iran. During a parasitological field survey in central parts of Iran in 2018, thirty-two cestodes, as an obstructive intertwined mass, recovered from the intestine of a recently dead Parus major (great tit). Morphological characteristics of recovered cestodes were drawn carefully by a camera lucida equipped microscope and identification was carried out using standard keys. All of the collected cestodes were identified as P. parina. In the current study, we recorded P. parina from great tit for the first time in Iran.
Risk Factors Analysis of Malaria Transmission at Cross-Boundaries Area in Menoreh Hills, Java, Indonesia
Authors: Sri Rejeki Dwi Sarwani , Solikhah Solikhah , M Wijayanti Siwi Pramatama
Published: September 2021

Background: Risk factors of Malaria transmission at cross-boundaries area is important to be identified. This study aimed to identify the risk factors of Malaria transmission at cross-boundaries area in Menoreh Hills, Java, Indonesia.
Methods: The design of the study was an observational study with a case-control design. Data on malaria cases and controls were obtained from the Primary Health Care in Menoreh. All malaria positive patients with clinical and laboratory examinations recorded in health services during 1 Jan 2015-31 Dec 2015. Overall, 138 cases and 138 controls were included. Several variables were collected such as altitude, night out behavior, the use of mosquito nets, nighttime bed, travel history, mosquito bite prevention activities, cattle ownership, distance to mosquito breeding site, etc. Data were obtained by structured questionnaires and observation. Data were analyzed by univariate, bivariate and multivariate
Results: The altitude of house >500 m above sea level proved to be influential as a risk factor for Malaria (OR 3.62, 95% CI 1.61-8.16, P=0.002). Several variables were identified as a risk factor of Malaria such as the wall of the house from bamboo/wood, no insecticide and distance of house <100 m from mosquito breeding site.
Conclusion: An awareness for the local health sector particularly to provide a recommendation for house construction to protect a community from Malaria transmission.
Risk Factors Related to Falling in Patients after Stroke
Authors: Djurovic Olivera , Mihaljevic Olgica , Radovanovic Snezana , Kostic Smiljana , Vukicevic Marjana , Brkic Biljana Georgievski , Stankovic Snezana , Radulovic Danijela , Vukomanovic Ivana Simic , Radevic Svetlana R
Published: September 2021

Background: The aim of this study was to identify the risk factors associated with falling in post stroke patients.
Methods: This retrospective case-control study included 561 neurology patients hospitalized for a stroke and divided into two groups: falling patients and non-falling patients. They referred to the Special Hospital for Cerebrovascular Diseases "Sveti Sava" in Belgrade, Serbia, from 2018- 2019. Logistic regression analysis was applied to examine socio-economic factors associated with predictors of unmet healthcare needs.
Results: A significant difference was seen in the length of hospitalization of falling patients compared to the non-falling (P<0.001). We established statistically significant differences in mental status (P<0.001), sensibility (P=0.016), depressed mood (P<0.001), early (P=0.001) and medium insomnia (P=0.042), psychomotor slowness (P=0.030), somatic anxiety (P=0.044) and memory (P<0.001).
Conclusion: Cerebrovascular disease distribution and the degree of neurological deficit primarily altered mental status, which could be recognized as one of the more important predictors for falling after stroke. The identification of risk factors may be a first step toward the design of intervention programs for preventing a future fall among hospitalized stroke patients.
Synthesis, Cytotoxicity Evaluation, and Antifungal Activity of Novel Nitroglycerin Derivatives against Clinical Candida albi-cans Isolates
Authors: Rashidi Niloofar , Rezaie Sassan , Hashemi Sayed Jamal , Habibi Aziziollah , Baghersad Mohammad Hadi , Daie Roshanak , Khodavaisy Sadegh , Bakhshi Heidar , Salimi Ali , Getso Mohammad Ebraim , Rafat Zahra
Published: September 2021

Background: Candida albicans remains the main cause of candidiasis in most clinical settings. Available drugs for candidiasis treatment have many side effects. In this work, novel nitroglycerin derivatives were synthesized and their cytotoxic and antifungal effects evaluated against fluconazole susceptible and resistant clinical C. albicans isolates.
Methods: This experimental study was performed in Tehran University of Medical Sciences and Baqiatallah University of Medical Sciences, Tehran, Iran between Feb to Dec 2019. The in vitro activities of two novel nitroglycerin derivatives (1b and 2b) against 25 clinical fluconazole-susceptible and resistant C. albicans isolates and four standard C. albicans strains were determined according to CLSI reference M27-A3 documents. The cytotoxicity of chemical compounds was investigated near the SNL76/7 cells by colorimetric assay. Real-time PCRs were performed to evaluate the alterations in the regulation of ERG11 and CDR1 genes under nitroglycerin derivatives-treated and untreated conditions.
Results: The derivatives 1b and 2b exhibited potent antifungal activity against C. albicans isolates; MICs and MFCs varied from 18 μg/ml to 72 μg/ml and 36 μg/ml to 144 μg/ml, respectively. The cell viability evaluation demonstrated that both chemical compounds are safe within 24h. The nitroglycerin derivatives were able to reduce the transcription level of CDR1 and ERG11 genes in all susceptible and resistant C. albicans isolates.
Conclusion: Considering the potential and efficacy of these compounds against clinical C. albicans isolates, the complementary in vivo and clinical trials should be investigated.
Frequency of HLA Alleles in a Group of Severe COVID‐19 Irani-an Patients
Authors: Hamidi Farahani Ramin , Esmaeilzadeh Emran , Nezami Asl Amir , Heidari Mohammad Foad , Hazrati Ebrahim
Published: September 2021

Background: Human Leukocyte Antigen (HLA) system composed of a group of related proteins with important functions in the immune system. Several studies have reported that there is a significant association between specific HLA alleles and the susceptibility to different infectious diseases. This study aimed to detect the specific HLA alleles that cause higher susceptibility to COVID-19, we analyzed the HLA allele frequency distribution in Iranian patients with a severe form of COVID-19.
Methods: Overall, 48 severe cases of COVID-19 that were hospitalized and required intensive care unit (ICU) admission between Oct and Dec 2020 were included in this study. Genomic DNA was extracted from the peripheral blood samples and HLA typing (Locus A, B, and DR) was performed for the patients.
Results: After analyzing and comparing the results with a reference group of 500 Iranian individuals, a significant association was found for HLA-B*38, HLA-A*68, HLA-A*24, and HLA-DRB1*01.
Conclusion: These results may be valuable for studying the potential association of specific HLA alleles with susceptibility to COVID-19 and mortality due to the disease.
Investigating the relationship between leadership style of nursing department managers and work engagement in faculty members of Iranian universities of medical sciences
Authors: KhoshKesht S , Yaghoobzadeh A , Dehghan-nayeri‏ N
Published: September 2021

Introduction: The success of an organization is determined by its human ‎resources. Work engagement leads to higher productivity and performance of the organization. Leaders seek to understand the impact of ‎their leadership style on work engagement. This is even more important in educational organizations but research in this area is insufficient. This study aimed to investigate the relationship between department ‎manager’s leadership styles and faculty member’s work engagement in some Iranian universities of medical ‎sciences‎.
Methods: This was a descriptive-analytical correlational study. 149 people including faculty members and department managers with at least 6 months of work experience were selected through the convenience sampling method. Data collection tools included ‎a demographic questionnaire, a multi-factor leadership questionnaire, and a Schaufeli & Bakker work engagement questionnaire whose validity and reliability were examined. ‎Data were analyzed using SPSS software version 16.
Result: A total of 114 faculty members with 13.42 ± 9.75 and 35 department managers with 19.91 ± 8.67 work experience participated in this study. Faculty members reported high work engagement. There was a positive and significant relationship between work engagement and interactional (P = 0.010) and transformational leadership (P = 0.001). ‎There was a significant difference between manager’s and employee’s views on the interactional ‎and transformational leadership (P < 0.001).
Conclusion: Managers can promote job engagement by selecting the proper leadership style, and the advantages can be leveraged to boost organizational productivity.
Strategies to improve clinical confidence in nursing students' c: A Narrative review
Authors: Ahrari Sh , Heshmati-Nabavi F , Toghian-Chaharsoughi N
Published: September 2021

Introduction: Universities are responsible for nurturing nurses who have clinical skills and confidence. Self-confidence is one of the main components of clinical work and, nursing students have more efficient self-confidence. This review study aimed to find strategies for self-confidence improvement in nursing students.
Methods: To conduct this review study initially, using the keywords self-confidence, professional self-confidence and the self-confidence of nursing students in Persian and English, separately and in combination, between 2008 and 2018, a total of 1536 articles were obtained from Medline, CINAHL, ProQuest, Ovid and Science Direct databases. The full text of the articles was reviewed for inclusion and exclusion criteria and finally, 16 articles were selected for the final analysis.
Result: The findings indicated the efficacy of the short-term educational program on self-confidence skills of baccalaureate nursing students. Studies have shown that students demonstrate greater abilities in terms of knowledge, critical thinking, clinical understanding, or satisfaction upon simulation-based learning.
Conclusion: Simulation-based nursing educational interventions have strong and special educational effects in the field of psychology, especially in promoting the self-confidence of nursing students. Therefore, due to its positive effect on students' self-confidence, this method is proposed as a superior educational method in nursing students.
Post-Covid-19 Higher Education Scenarios and Future Strategic Orientations of Education
Authors: Kalavani Khalil , Dehnavieh Reza , Emadi Samira
Published: September 2021

The article's abstract is not available.
The Problems of Reopening Schools during the Coronavirus 2019 Epidemic
Authors: Rahbar Karbasdehi Ebrahim , Rahbar Karbasdehi Fatemeh
Published: September 2021

The article's abstract is not available.
Netiquette and its application in virtual learning: a vital necessity in medical universities during the Coronavirus pandemic
Authors: Moradi Eshagh , Amir pour saeid Fatemeh
Published: September 2021

The article's abstract is not available.
Las voces de las nadies: la prosa galeana y las mujeres de los sures
Authors: Calderón Mendoza Gonzalo Esteban
Published: September 2021

Las mujeres que han construido las historias de los sures acaecen como vidas y personas guerreras en lanarrativa de Eduardo Galeano. Contra la condena que intenta reducirlas a ser nadies en las tradicionescientíficas e históricas oficiales, irrumpen como energías fonémicas, textuales, dibujantes ylogodisruptivas. Galeano, como un buen traductor cultural, solo hizo algunas grafías y pictogramasacerca de ellas, que son las verdaderas protagonistas de estas líneas. Aquellas que no fungieron comomusas, sino como coautoras de una literatura breve, cotidiana y reivindicativa. Aquí, por ese derroterosentipensante y desde un análisis teórico-político e historiográfico de su prosa, se pretende elucidarcómo Galeano fue otra firma con la que ellas también sellaron –y sellan− sus letras. Una firma paraerigir y revalorizar sus memorias (contra)históricas (individuales y colectivas) usando la narrativa comoherramienta de emancipación social.
Rank distribution of wood removal from forest land
Authors:   Siberian Federal University, Mokhirev A.P. , Rukomojnikov K.P. ,   Volga State University of Technology, Mazurkin P.M. ,   Volga State University of Technology
Published: September 2021

The article is devoted to the problem of modeling the speed of movement of timber trucks in various natural conditions of the Krasnoyarsk Territory. The results were obtained on the basis of multiple observations of the speed of timber trucks on various sections of forest roads. The results presented in the article are based on the selection and analysis of factors that can presumably have any effect on the speed of movement of timber trucks when hauling timber. The article presents the results of creating a multifactorial dependence for calculating the speed of timber transport. The analysis of the quality factor of each of the factors is carried out by the rank distribution of the obtained regularities and by compiling a rating of the conducted field experiments on the multivariate analysis of timber removal. The calculations and modeling were carried out in the CurveExpert-1.40 software environment and the Microsoft Office Excel software package in the RANK environment. Using the CurveExpert-1.40 software environment, the adequacy of the regularities of the rank distributions of the factors of timber removal from the forest area was assessed by the correlation coefficient. As a result, we obtained models of the total and private influence of factors from themselves (monar ratio) by ranks, which were placed before modeling for each factor in the direction of changing the level of their preference for factors from worse to better. When analyzing the quality factor of experiments, all analyzed factors received a correlation coefficient above 0,97, which corresponds to the level of adequacy of the «strongest factor relationship». This made it possible to add up the ranks of all 35 factors and, by the sum of the ranks, reveal the rating in the system of factors. The paper presents the mathematical dependences of rank distributions and graphs constructed from them. As a result of modeling, regression dependences were obtained and the quality factor of the values of the factors used by the authors in the course of production experiments was proved.
Evaluación ex post a un programa municipal de reciclaje
Authors: Fernández Chávez Claudia Andrea , Fernández Chávez Jorge Carlos Alejandro , Cruz Julia Otilia Sagástegui
Published: September 2021

Los programas de reciclaje se crean para mejorar la calidad del ambiente y proteger la salud de las personas, fomentando a su vez una cultura de reciclaje y un mejor aprovechamiento de los residuos sólidos entre los ciudadanos. Sin embargo, estos programas contienen planes que usualmente no se logran cumplir a cabalidad.Por ello, este artículo tuvo como objetivo realizar una evaluación ex post del «Programa de segregación en la fuente y recolección selectiva de residuos sólidosmunicipales en el distrito de Trujillo» para el periodo 2016-2017. Esta es la base para determinar oportunidades de mejora y asegurar que la experiencia sea replicable en las siguientes implementaciones de este programa pues, a la fecha, no existe un documento que evalúe sus resultados de manera integral.El diseño de la investigación fue no experimental, de tipo descriptivo y cualitativo, utilizando como técnica el análisis documental. Se concluyó que de los cincocriterios evaluados, en el año 2017 solo se cumplió el criterio de eficacia, mas no los criterios de pertinencia, eficiencia, impacto y sostenibilidad en ambos años
Interdisciplinary art education and primary teaching students' self-confidence
Authors: Nalbur Vicdan
Published: September 2021

The purpose of this research is to determine whether the self-confidence of students receiving interdisciplinary arts education in primary school varies according to gender, age and the type of high school they graduated from. The research is designed in survey model. At the stage of determining the sample, the students who were educated at Marmara University Atatürk Faculty of Education and who received interdisciplinary art education were determined and the students to be included in the study were determined by random (random) 112 volunteers selections. The self-confidence scale developed by Akin (2007) was used to determine the self-confidence levels of the students participating in the study. When the research findings are examined; self-confidence scores of the students were found to be quite high. In addition, it was observed that the self-confidence scores of the students did not vary according to gender, age and the type of high school they graduated from.

KEYWORDS: Art Education; Clip; Dance; Self-Confidence; Short Film
Validity of the scoring system for traumatic liver injury: a generalized estimating equation analysis
Authors: Lee Kangho , Ryu Dongyeon , Kim Hohyun , Jeon Chang Ho , Kim Jae Hun , Park Chan Yong , Yeom Seok Ran
Published: September 2021

Purpose: The scoring system for traumatic liver injury (SSTLI) was developed in 2015 to predict mortality in patients with polytraumatic liver injury. This study aimed to validate the SSTLI as a prognostic factor in patients with polytrauma and liver injury through a generalized estimating equation analysis. Methods: The medical records of 521 patients with traumatic liver injury from January 2015 to December 2019 were reviewed. The primary outcome variable was in-hospital mortality. All the risk factors were analyzed using multivariate logistic regression analysis. The SSTLI has five clinical measures (age, Injury Severity Score, serum total bilirubin level, prothrombin time, and creatinine level) chosen based on their predictive power. Each measure is scored as 0–1 (age and Injury Severity Score) or 0–3 (serum total bilirubin level, prothrombin time, and creatinine level). The SSTLI score corresponds to the total points for each item (0–11 points). Results: The areas under the curve of the SSTLI to predict mortality on post-traumatic days 0, 1, 3, and 5 were 0.736, 0.783, 0.830, and 0.824, respectively. A very good to excellent positive correlation was observed between the probability of mortality and the SSTLI score (γ=0.997, P<0.001). A value of 5 points was used as the threshold to distinguish low-risk (<5) from high-risk (≥5) patients. Multivariate analysis using the generalized estimating equation in the logistic regression model indicated that the SSTLI score was an independent predictor of mortality (odds ratio, 1.027; 95% confidence interval, 1.018–1.036; P<0.001). Conclusions: The SSTLI was verified to predict mortality in patients with polytrauma and liver injury. A score of ≥5 on the SSTLI indicated a high-risk of post-traumatic mortality.
Same Brain, Different Look? – the Impact of Scanner, Sequence and Preprocessing on Diffusion Imaging Outcome Parameters
Authors: Thieleking Ronja , Zhang Rui , Paerisch Maria , Wirkner Kerstin , Anwander Alfred , Beyer Frauke , Villringer Arno , Witte A. Veronica
Published: September 2021

In clinical diagnostics and longitudinal studies, the reproducibility of MRI assessments is of high importance in order to detect pathological changes, but developments in MRI hard- and software often outrun extended periods of data acquisition and analysis. This could potentially introduce artefactual changes or mask pathological alterations. However, if and how changes of MRI hardware, scanning protocols or preprocessing software affect complex neuroimaging outcomes from e.g. diffusion weighted imaging (DWI) remains largely understudied. We therefore compared DWI outcomes and artefact severity of 121 healthy participants (age range 19-54 years) who underwent two matched DWI protocols (Siemens product and Center for Magnetic Resonance Research sequence) at two sites (Siemens 3T Magnetom Verio and Skyrafit). After different preprocessing steps, fractional anisotropy (FA) and mean diffusivity (MD) maps,obtained by tensor fitting, were processed with tract-based spatial statistics (TBSS). Inter-scanner and inter-sequence variability of skeletonised FA values reached up to 5% and differed largely in magnitude and direction across the brain. Skeletonised MD values differed up to 14% between scanners. We here demonstrate that DTI outcome measures strongly depend on imaging site and software, and that these biases vary between brain regions. These regionally inhomogeneous biases may exceed and considerably confound physiological effects such as ageing, highlighting the need to harmonise data acquisition and analysis. Future studies thus need to implement novel strategies to augment neuroimaging data reliability and replicability.
Chick Embryo Experimental Platform for 3D Tissue Engineering Modelling of Cancer Micrometastases for Tumor Biology, Drug Development and Nanomaterials Testing
Authors: Guller Anna , Kuschnerus Inga , Rozova Vlada , Nadort Annemarie , Yao Yin , Khabir Zahra , Garcia-Bennett Alfonso , Liang Liuen (Olivia) , Polikarpova Aleksandra , Qian Yi , Goldys Ewa M. , Zvyagin Andrei
Published: September 2021

Colonization of distant organs by tumor cells is a critical step of cancer progression. The initial avascular stage of this process (micrometastasis) remains almost inaccessible to study due to the lack of relevant experimental approaches. Here, we introduce an in vitro/in vivo model of organ-specific micrometastases of triple-negative breast cancer (TNBC) that is fully implemented in a cost-efficient chick embryo (CE) experimental platform. The model is built as three-dimensional (3D) tissue engineering constructs (TECs) combining human MDA-MB-231 cells and decellular-ized CE organ-specific scaffolds. TNBC cells colonized CE organ-specific scaffolds in 2-3 weeks, forming tissue-like structures. The feasibility of this methodology for basic cancer research, drug development and nanomedicine was demonstrated on a model of hepatic micrometastasis of TNBC. We revealed that MDA-MB-231 differentially colonize parenchymal and stromal com-partments of the liver-specific extracellular matrix (LS-ECM) and become more resistant to the treatment with molecular Doxorubicin (Dox) and Dox-loaded mesoporous silica nanoparticles than in monolayer cultures. When grafted on CE chorioallantoic membrane, LS-ECM-based TECs induced angiogenic switch. These findings may have important implications for the diag-nosis and treatment of TNBC. The methodology established here is scalable and adaptable for pharmacological testing and cancer biology research of various metastatic and primary tumors.
Primordial Planets with an Admixture of Dark Matter Particles and Baryonic Matter
Authors: O.V. Kiren , Kenath Arun , C Sivaram , K.T. Paul
Published: September 2021

In our earlier work we had discussed the possibility of primordial planets composed entirely of dark matter (DM) to be the main reason for not detecting DM particles. It has been suggested that primordial planets could have formed in the early Universe and the missing baryons in the Universe could be explained by primordial free-floating planets of solid hydrogen. Many such planets were recently discovered around the old and metal poor stars and such planets could have formed at early epochs. Another possibility for missing baryons in the Universe could be that these baryons are admixed with DM particles inside the primordial planets. Here we discuss the possibility of admixture of baryons to the DM primordial planets discussed in earlier work. We consider gravitationally bound DM objects with the DM particles constituting them varying in mass from 20 – 100GeV. Different fractions of DM particles mixed with baryonic matter in forming the primordial planets are discussed. For the different mass range of DM particles forming DM planets, we have estimated the radius and density of these planets with different fractions of DM and baryonic particles. It is found that for heavier mass DM particles with the admixture of certain fractions of baryonic particles, the mass of the planet increases and can reach or even substantially exceed Jupiter-mass.