bluuebunny/crossref_metadata_2025 huggingface dataset:
Fostering Care Through Core Reflection
Authors: Berg Margaret H.
Published: August 2023

Core reflection involves “inside-out” or “learning from within” approaches, wherein teachers focus on strengths rather than deficits to envision positive ways to address challenges. It involves five phases: (a) describing a concrete situation or problem; (b) reflection on the ideal (in a situation) and core qualities; (c) reflection on an obstacle; (d) using the core potential; and (e) trying a new approach. This chapter begins with a school orchestra teacher engaged in reflective thinking during a post-rehearsal reflection. Next, core reflection concepts are presented, then illustrated in an expanded version of the initial post-rehearsal reflection. The chapter concludes with a discussion of connections between core reflection and care and a brief description of core reflection resources.
“I Just Wanna Live My Life Like It’s Gold”
Authors: Tsui Alice A. , Hess Juliet , Hendricks Karin S.
Published: August 2023

Music has played a key role in social activism and resistance to oppressive structures and regimes (Hess, 2019). Music education presents an opportunity to create spaces in which student voices are valued. Anti-racist music education disrupts supremacist narratives and traditions, recognizes the various contributions that students bring, and de-centers the teacher as “expert,” thereby affording the teacher space to continue to learn and grow along with other music learners—similar to the notion of “caring with” in compassionate music teaching (Hendricks, 2018, 2021). This chapter describes anti-racist arts integration programming at New Bridges Elementary, New York City, in which students respond to the Black Lives Matter movement and where Black, Brown, Latinx, and immigrant student voices are affirmed.
In Search of Meaning, Joy, and Justice in Music Education
Authors: Mota Graça
Published: August 2023

In this chapter the meaning of education, music education, and music teacher education, is approached under the focus of its contribution toward a democratic, and more just society. Drawing on the writings of Gert Biesta regarding education and arts education, a proposal is made to bring about significant changes in music teacher education toward a project-based curriculum that includes the construction of objects of experience, and moral responsibility and care. The central role of research is considered according to the agenda outlined by David E. Myers, and within a context of societal relevance. An appeal is made to music educators to engage actively in the process of overcoming educational inequalities.
A Call for Care and Compassion in Music Education
Authors: Hendricks Karin S.
Published: August 2023

Notions of care and compassion are sometimes misunderstood in the context of music education—equated simply with kindness or associated falsely with lowered expectations—and are often dismissed without consideration of their full value to music learning. Many well-intended, but limited, perspectives on care emphasize a unidirectional relationship from teacher to student and do not fully account for the ways in which a teacher also continues to learn and develop. Furthermore, caring for students through a “deficit” perspective might evoke unnecessary pity or a sense of rescue, thereby positioning music teachers and learners in a superior/inferior relationship that may be unhealthy or unhelpful for either person. This chapter explores conceptualizations of compassionate care in music education as caring for, about, and with students. It explores the following topics: (a) philosophical perspectives on care; (b) co-creating caring relationships; (c) wellbeing and human flourishing, and (d) social activism and critical consciousness.
An Ethic of Expectation Surrounding the Virtual Performance
Authors: Talbot Brent C. , Bernard Cara Faith
Published: August 2023

Preparing virtual performances presents a set of tensions for music educators to consider and negotiate, including access to resources, technology, physical spaces, and labor; and the dilemma of manipulating student’s recordings to create a polished product. Amid these tensions lies a possibility that the virtual performance might become the benchmark toward which music educators are expected to strive, and on which music educators might be evaluated. In this chapter, we examine the ethics surrounding the often perceived and/or (in)directly communicated expectation for creating and producing a virtual performance. Framed through what we term an ethic of expectation, we consider ways music educators might model compassion and allow for flexibility within the virtual performance.
Opioid Use Disorder
Authors: Ware Orrin D. , Dunn Kelly E.
Published: August 2023

Appropriately diagnosing disorders is necessary to provide treatment to individuals in need. Diagnostic criteria should be empirically supported and reliable. Opioid use disorder (OUD) is currently defined by a set of criteria which clinicians, patients, policymakers, and researchers can use to appropriately diagnose the disorder. The Diagnostic and Statistical Manual of Mental Disorders (DSM) is the predominate method of determining mental health diagnoses in the United States and has undergone numerous revisions from the first edition in 1952. This chapter will introduce the historical changes to the DSM as it relates to OUD. We will also provide readers with a clinical impact of the current DSM-5 OUD diagnostic criteria. This chapter will conclude with a case example which directly pertains to OUD diagnoses.
Use of a Shear Reduction Surface for Prehospital Transport: A Randomized Crossover Study
Authors: Tescher Ann N. , Berns Kathleen S. , Call Evan , Koehler Patrick J. , Salzwedel Kip W. , McCormack Heather E. , Myers Lucas A. , Hagen Clinton E. , Mandrekar Jay , Russon Marianne
Published: August 2023

OBJECTIVE

To compare the effectiveness of an antishear mattress overlay (ASMO) with a standard ambulance stretcher surface in reducing pressure and shear and increasing patient comfort.

METHODS

In this randomized, crossover design, adults in three body mass index categories served as their own controls. Pressure/shear sensors were applied to the sacrum, ischial tuberosity, and heel. The stretcher was placed in sequential 0°, 15°, and 30° head-of-bed elevations with and without an ASMO. The ambulance traveled a closed course, achieving 30 mph, with five stops at each head-of-bed elevation. Participants rated discomfort after each series of five runs.

RESULTS

Thirty individuals participated. Each participant had 30 runs (15 with an ASMO, 15 without), for a total of 900 trial runs. The peak-to-peak shear difference between support surfaces was −0.03 N, indicating that after adjustment for elevation, sensor location, and body mass index, peak shear levels at baseline (starting pause) were 0.03 N lower for the ASMO than for the standard surface (P= .02). The peak-to-peak pressure difference between surfaces was −0.16 mm Hg, indicating that prerun peak-to-peak pressure was 0.16 mm Hg lower with the ASMO versus standard surface (P= .002). The heel received the most pressure and shear. Discomfort score distributions differed between surfaces at 0° (P= .004) and 30° (P= .01); the overall score across all elevations was significantly higher with the standard surface than with the ASMO (P= .046).

CONCLUSIONS

The ASMO reduced shear, pressure, and discomfort. During transport, the ambulance team should provide additional heel offloading.
Insufficient Workplace Infection Control and Unhealthy Lifestyle Behaviors Are Related to Poor Self-Rated Health During the COVID-19 Pandemic
Authors: Inoue Yukiko , Nakata Akinori , Tateishi Seiichiro , Mafune Kosuke , Tsuji Mayumi , Ogami Akira , Odagami Kiminori , Matsugaki Ryutaro , Fujino Yoshihisa ,   for the CORoNa Work Project
Published: August 2023

Objective

This study investigated whether workers who practiced unhealthy lifestyles but worked under organizations with insufficient control against coronavirus disease 2019 (COVID-19) would pose a synergistic risk of poor self-rated health (SRH).

Methods

A total of 22,637 workers (men, 48.5%) were extracted from an online survey during the COVID-19 pandemic in Japan (December 2020). Multiple logistic regression analyses were performed to estimate adjusted odds ratio (AOR) against poor (poor, fair) SRH.

Results

Accumulation of unhealthy lifestyle behaviors (AOR, 1.49 to 4.40; P < 0.05) and insufficient infection control (AOR, 1.80; P < 0.05) were independently related to poor SRH; however, when these factors were combined, SRH was additively worsened (AOR, 2.14 to 7.72; P < 0.05).

Conclusions

This study highlights that not only unhealthy lifestyle practices but also poor organizational management against infection would worsen workers' SRH during the COVID-19 pandemic.
Screening and Referral for Behavioral Health Symptoms in Collegiate Athletes
Authors: Thompson Tyler , Kaplan Sebastian , Conway Rachel , Miles Christopher
Published: August 2023

Objective:

We aim to investigate the prevalence of behavioral health symptoms in collegiate athletes and the frequency of referrals prompted by a preparticipation behavioral health screener.

Design:

Athletes completed a screening battery to detect behavioral health symptoms and sports psychology clinicians designed criteria for intervention based on the severity of symptoms reported. Data from the screener was retrospectively de-identified and analyzed.

Setting:

National Collegiate Athletic Association Division-I university.

Participants:

All athletes on active rosters were required to complete the screener as a component of the preparticipation examination.

Interventions:

Sports psychology clinicians created a protocol for intervention based on the number and severity of symptoms reported on the screener.

Main Outcome Measures:

Communication with athletes and referrals made to behavioral health services.

Results:

Of the 1126 surveys completed, 39% had behavioral health symptoms necessitating behavioral health referral. Twelve percent required a safety check-in, given the severity of their symptoms. Seven percent of the respondents were newly established with behavioral health services.

Conclusions:

Symptoms of behavioral health disorders are common among athletes and yet, for a myriad of reasons, many choose to forgo treatment. By implementing a behavioral health screening battery, the prevalence of behavioral health symptoms among athletes at our institution was elucidated and many athletes were newly established with behavioral health services. The tiered intervention protocol in this study allowed for appropriate assessment and triage of high-risk individuals, while simultaneously providing lower-risk individuals with appropriate resources. Surveillance for behavioral health symptoms among college athletes using a screening battery with a tiered intervention protocol can ensure at-risk athletes are identified, contacted, and referred to behavioral health services, potentially improving their athletic performance and overall well-being, while averting poor outcomes.
Nurse practitioner curriculum puzzle: Connecting all of the documents
Authors: Idzik Shannon , Holland Aimee Chism
Published: August 2023

Many organizations, foundational documents, and structures guide nurse practitioner (NP) educators. The number can be overwhelming for nurse practitioner faculty and administrators, but awareness and understanding are essential for developing high-quality NP programs. A set of five key questions is a starting place for NP faculty to identify documents that guide their NP program development and curricula. (1) Which states does your program meet state educational requirements for professional licensure or certification? (2) Which accreditor is your program accredited by? (3) Which certification examinations are your students prepared to take? (4) Which educational competencies/standards apply to your program? (5) Which professional or practice organizations might be influential to your program? The development of high-quality NP programs advances the protection of the public and upholds the reputation of the profession. Organizations, components of licensure, accreditation, certification, education, and practice (LACEP), and key documents from national organizations will be reviewed, including how each of these are complementary and different.
APOE2 gene therapy reduces amyloid deposition, and improves markers of neuroinflammation and neurodegeneration in a mouse model of Alzheimer disease
Authors: Jackson Rosemary J , Keiser Megan S , Meltzer Jonah C , Fykstra Dustin P. , Dierksmeier Steven E. , Melloni Alexandra , Nakajima Tsuneo , Tecedor Luis , Ranum Paul T. , Carrell Ellie , Chen YongHong , Holtzman David M. , Davidson Beverly L. , Hyman Bradley T.
Published: August 2023

Epidemiological studies show that individuals who carry the relatively uncommon APOE ε2 allele rarely develop Alzheimer disease, and if they do they have a later age of onset, milder clinical course, and less severe neuropathological findings than others with Alzheimer disease. The contrast is especially stark in comparison to the phenotype associated with the major genetic risk factor for Alzheimer disease, APOE ε4, which has an age of onset several decades earlier, as well as a more aggressive clinical course and notably more severe neuropathological findings, especially in terms of the amount of amyloid deposition. Even one APOE ε2 allele improves phenotype, but it is uncertain if that is due to the replacement of a more toxic allele by APOE ε2, or if APOE ε2 has a protective, neuro-modulatory effect. Here, we demonstrate that brain exposure to APOE2 via a gene therapy approach which bathes the entire cortical mantle in the gene product after transduction of the ependyma, rapidly ameliorates established Aβ plaque deposition, neurodegenerative synaptic loss, and, remarkably, reduces microglial activation in an APP/PS1 mouse model despite continued expression of human APOE4. This result suggests a promising protective effect of exogenous APOE2, revealing a cell non-autonomous effect of the protein on microglial activation. We also show that plaque associated microglia in the brain of patients who inherit APOE2 similarly have less microglial reactivity to plaques. These data raise the potential that an APOE2 therapeutic could be effective in Alzheimer disease even in individuals born with the risk ε4 allele.

One Sentence Summary

Introduction of ApoE2 using an AAV that transduces the ependymal cells of the ventricle causes a reduction in amyloid load and plaque associated synapse loss, and reduces neuroinflammation by modulating microglial responsiveness to plaques.
Itaconate stabilizes CPT1a to enhance lipid utilization during inflammation
Authors: Mainali Rabina , Buechler Nancy , Otero Cristian , Edwards Laken , Key Chia-Chi , Furdui Cristina , Quinn Matthew A.
Published: August 2023

One primary metabolic manifestation of inflammation is the diversion of cis-aconitate within the tricarboxylic acid (TCA) cycle to synthesize the immunometabolite itaconate. Itaconate is well established to possess immunomodulatory and metabolic effects within myeloid cells and lymphocytes, however, its effects in other organ systems during sepsis remain less clear. UtilizingIrg1knockout mice that are deficient in synthesizing itaconate, we aimed at understanding the metabolic role of itaconate in the liver and systemically during sepsis. We find itaconate aids in lipid metabolism during sepsis. Specifically,Irg1KO mice develop a heightened level of hepatic steatosis when induced with polymicrobial sepsis. Proteomics analysis reveal enhanced expression of enzymes involved in fatty acid oxidation in following 4-ocytl itaconate (4-OI) treatmentin vitro. Downstream analysis reveals itaconate stabilizes the expression of the mitochondrial fatty acid uptake enzyme CPT1a, mediated by its hypoubiquitination. Chemoproteomic analysis revealed itaconate interacts with proteins involved in protein ubiquitination as a potential mechanism underlying its stabilizing effect on CPT1a. From a systemic perspective, we find itaconate deficiency triggers a hypothermic response following endotoxin stimulation, potentially mediated by brown adipose tissue (BAT) dysfunction. Finally, by use of metabolic cage studies, we demonstrateIrg1KO mice rely more heavily on carbohydrates versus fatty acid sources for systemic fuel utilization in response to endotoxin treatment. Our data reveal a novel metabolic role of itaconate in modulating fatty acid oxidation during polymicrobial sepsis.
ALS iPSC-derived microglia and motor neurons respond to astrocyte-targeted IL-10 and CCL2 modulation
Authors: Allison Reilly L. , Ebert Allison D.
Published: August 2023

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the loss of upper and lower motor neurons (MNs). The loss of MNs in ALS leads to muscle weakness and wasting, respiratory failure, and death often within two years of diagnosis. Glial cells in ALS show aberrant expression of pro-inflammatory and neurotoxic proteins associated with activation and have been proposed as ideal therapeutic targets. In this study, we examined astrocyte-targeted treatments to reduce glial activation and neuron pathology using cells differentiated from ALS patient-derived iPSC carrying SOD1 and C9ORF72 mutations.

Specifically, we tested the ability of increasing interleukin 10 (IL-10) and reducing C-C motif chemokine ligand 2 (CCL2 / MCP-1) signaling targeted to astrocytes to reduce activation phenotypes in both astrocytes and microglia. Overall, we found IL10/CCL2NAb treated astrocytes to support anti-inflammatory phenotypes and reduce neurotoxicity, though through different mechanisms in SOD1 and C9ORF72 cultures. We also found altered responses of microglia and motor neurons to astrocytic influences when cells were cultured together rather than in isolation. Together these data support IL-10 and CCL2 as non-mutation-specific therapeutic targets for ALS and highlight the role of glial-mediated pathology in this disease.

Main Points (2-3 bulleted sentences, 250 characters including spaces)

Astrocyte-targeted IL-10 and neutralization of CCL2 reduce neuroinflammatory phenotypes in SOD1 and C9ORF72 models of ALS through divergent pathways.

ALS microglia and motor neurons in purified monocultures display altered reactivity to pro– and anti-inflammatory influences from astrocytes compared to co-cultures.
Ageing attenuates exercise-enhanced motor cortical plasticity
Authors: Curtin Dylan , Cadwallader Claire J. , Taylor Eleanor M. , Andrews Sophie C. , Stout Julie C. , Hendrikse Joshua J. , Chong Trevor T-J. , Coxon James P.
Published: August 2023

Cardiorespiratory exercise is known to modulate motor cortical plasticity in young adults, but the influence of ageing on this relationship is unknown. Here, we compared the effects of a single session of cardiorespiratory exercise on motor cortical plasticity in young and older adults. We acquired measures of cortical excitatory and inhibitory activity of the primary motor cortex using transcranial magnetic stimulation (TMS) from 20 young (M± s.d. = 25.30 ± 4.00 years) and 20 older (M± s.d. = 64.10 ± 6.50 years) healthy adults. Single and paired pulse TMS measures were collected before and after a 20-minute bout of high-intensity interval cycling exercise or an equivalent period of rest, and again after intermittent theta burst stimulation (iTBS). In both young and older adults, exercise led to an increase in glutamatergic excitation and a reduction in gamma-aminobutyric acid (GABA) inhibition. However, in contrast to younger adults, older adults showed an attenuated plasticity response to iTBS following exercise. These results demonstrate an age-dependent decline in cortical plasticity and indicate that a preceding bout of high-intensity interval exercise may be less effective for enhancing primary motor cortex plasticity in older adults. Our findings align with the hypothesis that the capacity for cortical plasticity is altered in older age.

Key points

Exercise enhances motor cortical plasticity in young adults, but how ageing influences this effect is unknown.

Here, we compared primary motor cortical plasticity responses in young and older adults before and after a bout of high-intensity interval exercise, and again after a plasticity-inducing protocol – intermittent theta burst stimulation.

In both young and older adults, exercise led to an increase in glutamatergic excitation and a reduction in gamma-aminobutyric acid (GABAergic) inhibition.

Our key result was that older adults showed an attenuated plasticity response to theta burst stimulation following exercise, relative to younger adults.

Our findings demonstrate an age-dependent decline in exercise-enhanced cortical plasticity and indicate that a preceding bout of high-intensity interval exercise may be less effective for enhancing primary motor cortex plasticity in older adults.
The motor apparatus of head movements in the Oleander hawkmoth (Daphnis nerii, Lepidoptera)
Authors: Prusty Agnish D. , Sane Sanjay P.
Published: August 2023

Head movements of insects play a vital role in diverse locomotory behaviors including flying and walking. Because insect eyes move minimally within their sockets, their head movements are essential to reduce visual blur and maintain a stable gaze. As in most vertebrates, gaze stabilization behavior in insects requires integration of both visual and mechanosensory feedback by the neck motor neurons. Whereas visual feedback is derived from the optic flow over the retina of their compound eyes, mechanosensory feedback is derived from their organs of balance, similar to the vestibular system in vertebrates. In Diptera, vestibular feedback is derived from the halteres – modified hindwings that evolved into mechanosensory organs – and is integrated with visual feedback to actuate compensatory head movements. However, non-Dipteran insects including Lepidoptera lack halteres. In these insects, vestibular feedback is obtained from the antennal Johnston’s organs but it is not well-understood how it integrates with visual feedback during head movements. Indeed, although head movements are well-studied in flies, the underlying motor apparatus in non-Dipteran taxa has received relatively less attention. As a first step towards understanding compensatory head movements in the Oleander hawkmothDaphnis nerii, we image the anatomy and architecture of their neck joint sclerites and muscles in using X-ray microtomography, and the associated motor neurons using fluorescent dye fills and confocal microscopy. Based on these morphological data, we propose testable hypotheses about the putative function of specific neck muscles during head movements, which can shed light on their role in neck movements and gaze stabilization.
Hemin decreases cellular aging and enhances healthspan and lifespan through the AMPK pathway
Authors: Zhang Yizhong , Naaz Arshia , Faidzinn Nashrul Afiq , Yogasundaram Sonia , Cheng Trishia Yi Ning , Jing Jovian Lin , Morel Gan Ingrid Wen-Hui Jeanette , Junqi Chen , Alfatah Mohammad
Published: August 2023

The quest to understand and manipulate the mechanisms of cellular aging has far-reaching implications for improving human health and longevity. Our comprehensive effort has led to the discovery of the intriguing anti-aging potential of hemin, an FDA-approved drug primarily used for the treatment of acute intermittent porphyria. Leveraging both yeast and human cell models, we investigate the multifaceted effects of hemin on extending cellular lifespan. Intriguingly, the involvement of the AMPK pathway emerges as a pivotal mechanism underlying hemin’s anti-aging effects. The exploration of hemin’s impact on cellular functionality further uncovers its influence on mitochondrial processes. Notably, both mitochondrial-dependent and -independent mechanisms are implicated in hemin’s ability to extend cellular lifespan, with autophagy playing a significant role in the latter. Additionally, a striking synergy between hemin and the TORC1 inhibitor rapamycin is unveiled, underlining the complexity of cellular signaling networks involved in lifespan extension. Translating these findings to human cells, hemin demonstrates an analogous ability to induce mitochondrial biogenesis, reduce proinflammatory cytokine expression, and enhance antioxidant response. The conservation of hemin’s anti-aging effects across species holds promise for therapeutic applications in addressing age-related diseases and promoting healthier aging.
Splenocytes and thymocytes migration patterns between lymphoid organs in pregnancy
Authors: Cruz-Cureño Gabriela T. , Rosales-Tarteaut Marina Ch. , Arriaga-Pizano Lourdes A. , Sánchez-Torres Luvia E. , Castro-Eguiluz Denisse , Prieto-Chávez Jessica L. , Pastelin-Palacios Rodolfo , Flisser Ana , Cérbulo-Vázquez Arturo
Published: August 2023

Background

Cell migration is essential for the immune system, and frequently is analyzing in adult non-pregnant animals, and poorly explored in pregnancy, however, a physiologic increase of size in the spleen and periaortic lymph nodes had been reported in pregnant mice.

Methods

Using a mouse model, we transferred PKH26-stained thymocytes and splenocytes from pregnant or non-pregnant animals to receptor mice in the presence or absence of pregnancy. Percentage and Mean Fluorescence Intensity were calculated by Flow cytometry in pregnant or non-pregnant mice. Non-parametric ANOVA analysis was performed.

Results

We detected that the percentage of PKH26+ thymocytes into the spleen, lymph nodes, and peripheral blood is higher in females than in males. Our results showed a similar frequency of thymocytes and splenocytes from pregnant and non-pregnant located into receptor lymphoid organs. Also, the location of marked cells was similar during the perinatal period.

Conclusions

The mobility of thymocytes and splenocytes in pregnant and non-pregnant mice is similar, therefore we suggest that the larger size of the spleen and periaortic lymph nodes noted previously in pregnant mice, could be the result of retention of leukocytes in the secondary lymphoid organs.
The evolution of sexual dimorphism in gene expression in response to a manipulation of mate competition
Authors: Mishra Prashastha , Rundle Howard D. , Agrawal Aneil F.
Published: August 2023

Many genes are differentially expressed between males and females and patterns of sex-biased gene expression (SBGE) vary among species. Some of this variation is thought to have evolved in response to differences in mate competition among species that causes varying patterns of sex-specific selection. We used experimental evolution to test this by quantifying SBGE and sex-specific splicing in 15Drosophila melanogasterpopulations that evolved for 104 generations in mating treatments that removed mate competition via enforced monogamy, or allowed mate competition in either small, simple or larger, structurally more complex mating environments. Consistent with sex-specific selection affecting SBGE, initially sex-biased genes diverged in expression more among treatments than unbiased genes, and there was greater expression divergence for male-than female-biased genes. It has been suggested the transcriptome should be ‘feminized’ under monogamy because of the removal of sexual selection on males; we did not observe this, likely because selection differs in additional ways between monogamy vs. polygamy. Significant divergence in average expression dimorphism between treatments was observed and, in some treatment comparisons, the direction of the divergence differed across different sex-bias categories. There was not a generalized reduction in expression dimorphism under enforced monogamy.
Metatranscriptomic analysis of common mosquito vector species in the Canadian Prairies
Authors: Baril Cole , Cassone Bryan J.
Published: August 2023

The microbiome plays vital roles in the life history of mosquitoes, including their development, immunity, longevity, and vector competence. Recent advances in sequencing technologies have allowed for detailed exploration into the diverse microorganisms harboured by these medically important insects. Although these meta-studies have catalogued the microbiomes of mosquitoes on several continents, much of the information currently available for North America is limited to the state of California. In this study, we collected >35,000 mosquitoes throughout Manitoba, Canada over a two-year period, and then harnessed RNA sequencing and targeted RT-PCR to characterize the microbiomes of the eight most pervasive and important vector and pest species. The consensus microbiome of each species was overwhelmingly composed of viruses, but also included fungi, bacteria, protozoa, and parasitic invertebrates. The microbial assemblages were heterogeneous between species, even within the same genus. We detected notable pathogens, including the causal agents of Cache Valley Fever, avian malaria, and canine heartworm. The remaining microbiome consisted largely of putatively insect-specific viruses that are not well characterized, including 17 newly discovered viruses from 10 different families. Future research should focus on evaluating the potential application of these viruses in biocontrol, as biomarkers, and/or in disrupting mosquito vectorial capacity. Interestingly, we also detected viruses that naturally infect honeybees and thrips, which were presumably acquired indirectly through nectar foraging behaviours. Overall, we provide the first comprehensive catalogue of the microorganisms harboured by the most common and important mosquito vectors and pests in the Canadian Prairies.
The synthesis and characterization of a series of cocrystals of an isoniazid derivative with butan-2-one and propan-2-one
Authors: Scheepers Matthew Clarke , Lemmerer Andreas
Published: August 2023

Four cocrystals containing N′-(butan-2-ylidene)pyridine-4-carbohydrazide (izbt) and one cocrystal containing N′-isopropylideneisonicotinohydrazide (izact) were synthesized by reacting isoniazid with either butan-2-one (for the former) or acetone (for the latter). The coformers used to synthesize the izbt cocrystals were 2,4-dihydroxybenzoic acid, 2,5-dihydroxybenzoic acid, 2-chloro-4-nitrobenzoic acid and 1-naphthoic acid. 1-Naphthoic acid was also used with izact to form a cocrystal. The 1:1 cocrystals are: N′-(butan-2-ylidene)pyridine-4-carbohydrazide–1-naphthoic acid (izbt–1nta), C10H13N3O·C11H8O2, N′-(butan-2-ylidene)pyridine-4-carbohydrazide–2,4-dihydroxybenzoic acid (izbt–2,4-dhba), C10H13N3O·C7H6O4, N′-(propan-2-ylidene)pyridine-4-carbohydrazide–1-naphthoic acid (izact–1nta), C9H11N3O·C11H8O2, N′-(butan-2-ylidene)pyridine-4-carbohydrazide–2-chloro-4-nitrobenzoic acid (izbt–2c4n), C10H13N3O·C7H4ClNO4, and N′-(butan-2-ylidene)pyridine-4-carbohydrazide–2,5-dihydroxybenzoic acid (izbt–2,5-dhba), C10H13N3O·C7H6O4. The cocrystals containing izbt were compared to those containing the same (or similar) coformers with izact that have been reported either here or in the Cambridge Structural Database (CSD). Most of the cocrystals showed different packing despite having the same hydrogen-bonding motifs. The cocrystals were characterized by single-crystal X-ray diffraction (SC-XRD), powder X-ray diffraction (PXRD) and differential scanning calorimetry (DSC).
Challenges of big data analytics for sustainable supply chains in healthcare – a resource-based view
Authors: Hussain Matloub , Ajmal Mian , Subramanian Girish , Khan Mehmood , Anas Salameh
Published: August 2023

Purpose

Regardless of the diverse research on big data analytics (BDA) across different supply chains, little attention has been paid to exploit this information across service supply chains. The healthcare supply chains, where supply chain operations consume the second highest expenditures, have not completely attained the potential gains from data analytics. So, this paper explores the challenges of BDA at various levels of healthcare supply chains.

Design/methodology/approach

Drawing on the resource-based view (RBV), this research explores the various challenges of big data at organizational and operational level of different nodes in healthcare supply chains. To demonstrate the links among supply chain nodes, the authors have used a supplier-input-process-output-customer (SIPOC) chart to list healthcare suppliers, inputs (such as employees) supplied and used by the main healthcare processes, outputs (products and services) of these processes, and customers (patients and community).

Findings

Using thematic analysis, the authors were able to identify numerous challenges and commonalities among these challenges for the case of healthcare supply chains across United Arab Emirates (UAE). An applicable exploration on organizational (Socio-technical) and operational challenges to BDA can enable healthcare managers to acclimate efficient and effective strategies.

Research limitations/implications

The identified common socio-technical and operational challenges could be verified, and their impacts on the sustainable performance of various supply chains should be explored using formal research methods.

Practical implications

This research advances the body of literature on BDA in healthcare supply chains in that (1) it presents a structured approach for exploring the challenges from various stakeholders of healthcare chain; (2) it presents the most common challenges of big data across the chain and finally (3) it uses the context of UAE where government is focusing on medical tourism in the coming years.

Originality/value

Originality of this work stems from the fact that most of the previous academic research in this area has focused on technology perspectives, a clear understanding of the managerial and strategic implications and challenges of big data is still missing in the literature.
Text classification using deep learning techniques: a bibliometric analysis and future research directions
Authors: Sarin Gaurav , Kumar Pradeep , Mukund M.
Published: August 2023

Purpose

Text classification is a widely accepted and adopted technique in organizations to mine and analyze unstructured and semi-structured data. With advancement of technological computing, deep learning has become more popular among academicians and professionals to perform mining and analytical operations. In this work, the authors study the research carried out in field of text classification using deep learning techniques to identify gaps and opportunities for doing research.

Design/methodology/approach

The authors adopted bibliometric-based approach in conjunction with visualization techniques to uncover new insights and findings. The authors collected data of two decades from Scopus global database to perform this study. The authors discuss business applications of deep learning techniques for text classification.

Findings

The study provides overview of various publication sources in field of text classification and deep learning together. The study also presents list of prominent authors and their countries working in this field. The authors also presented list of most cited articles based on citations and country of research. Various visualization techniques such as word cloud, network diagram and thematic map were used to identify collaboration network.

Originality/value

The study performed in this paper helped to understand research gaps that is original contribution to body of literature. To best of the authors' knowledge, in-depth study in the field of text classification and deep learning has not been performed in detail. The study provides high value to scholars and professionals by providing them opportunities of research in this area.
Development and validation of the InEquality in organisations Scale (InE-S): a measure based on Acker’s inequality regimes
Authors: Tafvelin Susanne , Keisu Britt-Inger
Published: August 2023

Purpose

The purpose of this study was to develop a scale that can be used to assess inequality at work based on gender, age and ethnicity that is grounded in Acker’s (2006) inequality regimes.

Design/methodology/approach

The authors used three representative samples (total N = 1,806) of Swedish teachers, nurses and social workers to develop and validate the scale. The validation process included the assessment of content validity, confirmatory factor analysis for factorial validity, internal consistency and associations with theoretically warranted outcomes and related constructs to assess criterion-related validity and convergent validity.

Findings

The authors found evidence supporting the content, factorial, criterion-related and convergent validity of the InEquality in organisations Scale (InE-S). Furthermore, the scale demonstrated high internal consistency.

Originality/value

The newly developed scale InE-S may be used to further the understanding of how inequality at work influences employees. This study makes a contribution to the current literature by providing a scale that, for the first time, can test Acker’s hypotheses using quantitative methods to demonstrate the consequences of inequality at work.
Health service use after moving on from permanent supportive housing
Authors: Aykanian Amanda , Tiderington Emmy
Published: August 2023

Purpose

Studies have shown positive housing retention and quality of life outcomes in moving on initiatives (MOIs). However, less is known about how movers’ health service use changes post-move. This paper aims to explore physical and mental health service use over time for participants in New York City’s MOI program.

Design/methodology/approach

This paper uses data collected at baseline, 12-months post move and 24-months post move to explore patterns in mental and physical health service use and their association with mental and physical health status for participants (N = 41). Health status was measured with the Medical Outcomes Study Short Form Survey Instrument.

Findings

Three mental health service use patterns emerged: service use at all time points, inconsistent service use across time points and no service use at any time point. Significant group differences in mental health were found at baseline and 12 months. Two physical health service use patterns emerged: service use at all three time points and inconsistent service use across time points. Significant group differences were found in mental health at 12  and 24 months.

Originality/value

This study showed that physical and mental health service use varied slightly over time for participants, with the majority of service use being for outpatient/non-acute care. The findings also point to possible relationships between service use and mental health status. Positive and negative implications of these findings are framed within the broader context of PSH and MOI goals.
Green innovation adoption of SMEs in Indonesia: what factors determine it?
Authors: Indrawati Henny , Caska Caska , Hermita Neni , Sumarno Sumarno , Syahza Almasdi
Published: August 2023

Purpose

An important global issue is the harm that businesses are posing to the environment. However, the impact of small and medium enterprises’ (SMEs) operations on the environment often goes unnoticed, and their willingness to adopt green innovations is limited. Therefore, this study aims to examine the factors influencing the adoption of green innovation among SMEs in Indonesia.

Design/methodology/approach

The research used a survey to investigate SMEs operating in the pineapple-based food sector, which is a leading commodity in Riau Province, Sumatera, Indonesia. Specifically, the research focused on the districts of Kampar, Siak and Dumai, with data collecting taking place from April to August 2022. SMEs were selected purposively based on a minimum operational tenure of 10 years. A total of 225 respondents met the selection criteria and participated in this study. The research data were collected through a questionnaire. To analyse the data, the study used structured equation modelling with partial least squares.

Findings

There are three categories of factors influencing SMEs to adopt green innovations: technological, environmental and organizational. Of these factors, organizational factors emerge as the primary determinant of green innovation adoption among SMEs in the country.

Research limitations/implications

The generalizability of the findings in this study is limited due to the specific focus on food sector SMEs in Riau Province. To obtain more generalized results, it is recommended that future research be conducted on SMEs across different sectors in other cities and countries.

Originality/value

This study provides a deeper understanding of the specific dimensions of organizational factors that play a crucial role in driving green innovation adoption, especially within the context of SMEs in the food sector in Indonesia.
Measures for achieving sustainable environment to mitigate climate change in Africa
Authors: Osei Bismark , Kunawotor Mark Edem , Appiah-Konadu Paul
Published: August 2023

Purpose

This study examines the appropriate measures that need to be intensified among African countries to achieve sustainable environment to mitigate climate change.

Design/methodology/approach

The study employs panel data covering the period 2000 to 2020 among 54 African countries and Cox proportional hazard model for the analysis.

Findings

Estimates indicate that the practice of carbon farming, the development of rooftop gardens, renewable energy production and consumption contribute positively toward achieving sustainable environment, while governance adversely affects this objective of achieving sustainable environment.

Practical implications

The study recommends that governments should enforce the constant practice of carbon farming among these countries through passing laws to enforce its application among farmers and allocate 2% of ministry of agriculture's budget toward financing carbon farming for poor farmers.

Originality/value

Empirical studies have been carried out exploring measures to deal with climate change. Nonetheless, the appropriate measures of achieving sustainable environment to mitigate climate change have less been explored in literature on Africa. Hence, this study fills the gap in existing empirical studies.

Peer review

The peer review history for this article is available at:https://publons.com/publon/10.1108/IJSE-04-2023-0290.
Study on the compressive residual strength after edge low-velocity impact of T300/69 laminates
Authors: Wei Yaobing , Wang Xuexue , Liu Jianhui , Li Jianwei , Pan Yichen
Published: August 2023

Purpose

Engineering composite laminates/structures are usually subjected to complex and variable loads, which result in interlayer delamination damage. However, damaged laminate may cause the whole structure to fail before reaching the design level. Therefore, the purpose of this paper is to develop an equivalent model to effectively evaluate compressive residual strength.

Design/methodology/approach

In this paper, taking carbon fiber reinforced composite T300/69 specimens as the study object, first, the compressive residual strength under different impact energy is obtained. Then, zero-thickness cohesive elements, Hashin failure criteria and Camanho nonlinear degradation scheme are used to simulate the full-process simulation for compression after edge impact (CAEI). Lastly, based on an improved Whitney–Nuismer criterion, the equation of edge hole stress distribution, characteristic length and compressive residual strength is used to verify the correctness of the equivalent model.

Findings

An equivalent relationship between the compressive residual strength of damaged laminates and laminates with edge hole is established. For T300/69 laminates with a thickness of 2.4 mm, the compressive residual strength after damage under an impact energy of 3 J is equivalent to that when the hole aperture R = 2.25 mm and the hole aperture R = 9.18 mm when impact energy is 6 J. Besides, the relationship under the same size and different thickness is obtained.

Originality/value

The value of this study is to provide a reference for the equivalent behavior of damaged laminates. An equivalent model proposed in this paper will contribute to the research of compressive residual strength and provide a theoretical basis for practical engineering application.
What makes learners enhance learning outcomes in MOOCs? Exploring the roles of gamification and personalization
Authors: Cheng Yung-Ming
Published: August 2023

Purpose

The purpose of this study is to propose a research model based on the stimulus-organism-response (S-O-R) model to explore whether gamification and personalization as environmental stimuli to learners’ learning engagement (LE) can affect their learning persistence (LP) in massive open online courses (MOOCs) and, in turn, their learning outcomes in MOOCs.

Design/methodology/approach

Sample data for this study were collected from learners who had experience in taking gamified MOOCs provided by the MOOCs platform launched by a well-known university in Taiwan, and 331 usable questionnaires were analyzed using structural equation modeling.

Findings

This study demonstrated that learners’ perceived gamification and personalization in MOOCs positively influenced their cognitive LE and emotional LE elicited by MOOCs, which jointly explained their LP in MOOCs and, in turn, enhanced their learning outcomes. The results support all proposed hypotheses and the research model, respectively, explaining 82.3% and 65.1% of the variance in learners’ LP in MOOCs and learning outcomes.

Originality/value

This study uses the S-O-R model as a theoretical base to construct learners’ learning outcomes in MOOCs as a series of the psychological process, which is influenced by gamification and personalization. Noteworthily, while the S-O-R model has been extensively used in prior studies, there is a dearth of evidence on the antecedents of learners’ learning outcomes in the context of MOOCs, which is very scarce in the S-O-R view. Hence, this study enriches the research for MOOCs adoption and learning outcomes into an invaluable context.
Antecedents of organizational ambidexterity: an empirical investigation of foreign ventures in an emerging market
Authors: Ju Min , Elliott Michael T.
Published: August 2023

Purpose

The purpose of this paper is to examine the antecedents of organizational ambidexterity of foreign ventures in an emerging market. Organizational ambidexterity, the simultaneous pursuit of exploration and exploitation, represents a key innovation strategy. Yet, the driving factors of such innovation strategies for foreign ventures competing in emerging markets have been underresearched. In this study, unpacking the construct of organizational ambidexterity into two dimensions (i.e. the combined dimension [CD] and the balance dimension [BD]), the authors aim to investigate how firm-level and industry-level factors drive foreign ventures in pursuing exploration and exploitation and maximizing the benefits of both.

Design/methodology/approach

This study adopts the hierarchical multiple regression approach using a sample of foreign ventures operating in high-tech manufacturing industries in China.

Findings

The authors find that the firm-level factor of strategic flexibility leads positively to the CD of organizational ambidexterity, whereas the industry-level factor of technological turbulence has a significantly positive impact on the BD.

Originality/value

This study provides important insights into the driving factors of organizational ambidexterity for foreign ventures competing in emerging markets.