bluuebunny/crossref_metadata_2025 huggingface dataset:
ESTIMATING RELATIVE IMPORTANCE OF RESILIENCE INDICATORS FOR LARGE-SCALE HOSPITAL BUILDINGS TO WITHSTAND HYDROLOGICAL DISASTERS
Authors: Gupta Niyati , Mathur Manoj , Dewan Anil
Published: August 2021

Purpose of the study: Uninterrupted hospital services and medical functions are the keys to functional resilience to cope with mass casualties. This paper presents the important level of resilience indicators for hospital functions to withstand natural disasters.

Methodology: For the survey, 21 indicators are grouped into three domains focusing on i) general concerns of healthcare infrastructure planning ii) design and planning of hospital buildings iii) emergency service and management. The corresponding indicators were ranked on a Likert scale of 1 to 5. The authors collected 389 responses through an online survey of the healthcare professionals including disaster management professionals, medical officers, hospital architects, planners, project managers, and engineers.

Main Findings: The data were analysed for determining the Relative Importance Index (RII) of each indicator. The top 7 indicators as an outcome of this research are: ‘access to the emergency services (0.861), ‘planning of refugee settlements’ (0.814), ‘uninterrupted supply of MEP services to critical units’ (0.871), ‘signages for internal circulation’ (0.845), ‘adaptive control, command, and communication system’ (0.848), ‘flexible spatial planning in case of a surge of patients’(0.813), ‘ensuring availability of healthcare workers with the provision of support infrastructure’ (0.758).

Applications of this study: Assessment of the top indicators highlight the importance of ‘flexible design’ and ‘access to medical functions of a hospital building’. Based on these outcomes, it is proposed to develop a numerical framework for a comprehensive design appraisal of resilient hospital buildings.
Praxis and challenges of Tour guides in Quirino province, Philippines
Authors: C. Erana Princess Lady-Lin , Tariga Jonathan N. , Baguilat Leah Grace R.
Published: August 2021

Purpose of the study: This study aims to determine the different tour guide practices and challenges in the Province of Quirino.

Methodology: This study uses the quantitative approach. Data collection techniques were interviews and questionnaires that were measured using a Likert scale. The questionnaire was distributed to 22 respondents who were tour guides of the different tourist destinations in the province. The data were analysed using SPSS with the Frequency Counts/ Percentage, Mean and F-test (ANOVA) as statistical tools.

Main Findings: The results of this study indicated most of the respondents are male. The tour guiding practices and the challenges in the province of Quirino is “Strongly Agree” when grouped by sex, age and ethnic affiliation. There is no significant difference on the tour guiding practices among the tour guides in the province of Quirino when grouped by sex and ethnic affiliation.

Implications: The ability of tour guides to provide exceptional service to tourists is crucial not just to the business's profitability, but also to the destination's reputation. As per recommended there should be an established system of on-gong training and assessment to maintain high standards in performance of tour guides. The provincial tourism should continue to improve their services especially more trainings and seminars will be given to the accredited tour guides in the province of Quirino. For a profession that was shifting to maintain its relevance in a world of apps and self-guided tours, this is another change that requires adaptation.

Originality: The study is original and novel, it explored the practices and challenges encountered by tour guides in our province.
Immunization training for pharmacy students: a student-centered evaluation
Authors: Mills Shaylee , Emmerton Lynne , Sim Tin F.
Published: August 2021

Background: Persistent and emerging public health challenges mean Pharmacy students require training in immunization services. Curtin University, Australia, integrated blended-delivery immunization training into the final-year Bachelor of Pharmacy (Hons) and graduate-entry Master of Pharmacy curricula in 2019 and 2020, utilizing materials licenced from the Pharmaceutical Society of Australia.

Objective: This study evaluated changes in students’ attitude, confidence, self-perceived knowledge and self-perceived skills pre- and post-training delivered in 2020.

Methods: Pre- and post-training questionnaires featured 42 opinion statements grouped under headings ‘Attitudes’, ‘Confidence’, ‘Self-Perceived Knowledge’ and ‘Self-Perceived Skills’, and answered using five-point Likert scales (1 = strongly disagree to 5 = strongly agree). Completed pre- and post-training questionnaires were matched using respondent-generated codes. Data were subjected to descriptive and multivariate regression analysis to test pre-post changes and associations and changes in mean scores.  

Results: 128 (95.5%) and 132 (98.5%) students completed the pre- and post-training questionnaires, respectively. Immunization training resulted in significant (p<0.05) improvement in students’ mean Confidence score (3.33 vs 3.96), Self-Perceived Knowledge score (3.08 vs 4.47) and Self-Perceived Skills score (2.81 vs 4.55). Improvement in students’ mean Attitude score was also statistically significant (4.45 vs 4.61), yet more positively skewed pre-training. No significant pre-post differences were found between the Bachelor and Master students. Post-training, all respondents agreed that the training program increased their attitude, confidence, perceived knowledge and perceived skills, rating the training experience as either Excellent (91.6%) or Good (8.4%).

Conclusions: Immunization training integrated into final-year BPharm (Hons) and MPharm curricula improved Attitudes, Confidence, Self-Perceived Knowledge and Self-Perceived Skills, all key to further role development in public health. This method is recommended to other Pharmacy schools to determine the impact and acceptability of immunization training programs amongst students.
Cardiovascular diseases and risk factors in kidney transplant candidates
Authors: KOCABAŞ Umut
Published: September 2021

Objectives: Cardiovascular diseases and risk factors are associated with adverse cardiac events following kidney transplant. Therefore, pre-transplant evaluation of cardiovascular diseases and risk factors is important for determining the cardiac risk. The objective of this study is to determine the prevalence of cardiovascular diseases and risk factors in kidney transplant candidates.
Methods: This is a single-center and observational study which includes 174 end-stage renal disease patients (male: 55.2% and mean age: 49 ± 13 years) who underwent kidney transplant. Preoperative clinical characteristics, cardiovascular diseases and risk factors of the patients were examined retrospectively.
Results: The study population had multiple cardiovascular risk factors such as hypertension (66.7%), diabetes (28.2%), dyslipidemia (29.9%) and smoking (30.5%) in the evaluation conducted prior to kidney transplant. The most common cardiovascular diseases were detected as congestive heart failure (10.9%) and coronary artery disease (8.6%). The rate of the patients who underwent myocardial revascularization (percutaneous coronary intervention or coronary artery bypass grafting) before kidney transplant was 6.9%. The patients’ mean left ventricular mass index was 114 ± 32 g/m2, and 55.5% of the study population had left ventricular hypertrophy.
Conclusions: In our study, the prevalence of cardiovascular diseases and risk factors in the patients who underwent kidney transplant was found to be high.
Contamination and health risk assessment of instant noodles by heavy metals from commercial outlets in Windhoek, Namibia
Authors:   Namibia University of Science and Technology, Awofolu Omotayo , Kakoma FIS
Published: September 2021

With growing international trade, food safety has emerged as an important global human health issue. One of the pathways by which extraneous contaminants such as toxic heavy metals access the human system is through food ingestion. At above permissible levels, these metals pose serious danger to human health. Cultivated farm produce on contaminated soil has the propensity to uptake and accumulate such contaminants. In this study, the prevalence and possible human health risks of toxic heavy metals such as Zinc, Cadmium, Copper, Lead, and Arsenic (Zn, Cd, Cu, Pb and As) in selected Instant Noodle Brands (INBs) from commercial outlets in Windhoek, Namibia was carried out. Different brands of instant noodle samples were purchased from four different commercial outlets for four periods with one-month interval. A total of 48 samples were collected and analysed for the level of heavy metals using mineral acid digestion method. Quantification of analysed metals in digested samples was done using Inductive Coupled Plasma -Optical Emission Spectrometer (ICP-OES). The mean concentration of heavy metals in the digested instant noodle samples across the sampling periods ranged from 13.1 – 17.9 mg/kg with overall mean concentration of 14.6mg/kg; 0.05 – 0.5mg/kg with overall mean level of 0.15 mg/kg; 1.5 – 2.4 mg/kg with overall mean concentration of 1.9 mg/kg; ND – 1.3 mg/kg with overall mean level of 0.4 mg/kg and 2.3 – 3.8 mg/kg with overall mean concentration of 1.4 mg/kg for Zn, Cd, Cu, Pb and As, respectively. A strong correlation (r = 0.99) was obtained between Zn and Cd levels but average correlation (r = 0.56) between Cd and Cu as well as between Cu and As (r= 0.55). Target Hazard Quotient (THQ) values greater than 1 (one) was obtained for Pb (1.7) and As (7.3). In addition, Carcinogenic Risk Index (CRI) values of 0.71 and 0.02 were also obtained for Pb and As, respectively. Of great concerns are the potential development of non-carcinogenic health effects and carcinogenic health risks with respect to these two toxic metals. Both metals are of no physiological benefits to the human system and very toxic at low levels. Hence, proper quality assurance protocol and monitoring of the level of toxic heavy metals in instant noodles products is recommended.
Therapeutic Evaluation of Florets of Musa acuminate in the Management of Rumen Lactacidosis in Goats
Authors: Mohanambal K. , Vijayakumar G.
Published: September 2021

Background: The present study was conducted to evaluate the efficacy of Musa acuminate flower floret (MAFF) extract/chopped in goats with moderate rumen lactacidosis. Methods: Goats affected with moderate rumen lactacidosis (MRLA) were divided into three groups. TC (Control): Eight goats with moderate rumen lactacidosis were administered with magnesium oxide (@ 1g/kg PO) through stomach tube, T1: Twenty four goats with MRLA were administered with aqueous extract of MAFF (either @ 1 ml/kg, 2 ml/kg or 4 ml/kg - PO) and T2: Twenty four goats with MRLA were administered with chopped MAFF (either @1 g/kg, 2 g/kg or 4 g/kg - PO) continuously for 5 days. Proximate, mineral and phytochemical compositions of MAFF were assessed by using standard protocol. Rumen fluid examination, consisting of pH, total protozoal count and bacterial count was assessed in addition to haematology and serum biochemical examination before and after administration of MAFF. Result: Goats with MRLA treated using chopped MAFF orally @ 4 gm/kg body weight or crude extract of the MAFF orally @ 2 ml/kg, 4 ml/kg body weight continuously for 5 days had restoration of (P less than 0.05) packed cell volume, increase in haemoglobin level, total protozoal count, gram negative bacterial count and rumen fluid pH and in serum PCO2 level (P less than 0.05) to the levels comparable to healthy animals.
DESENVOLVIMENTO E APLICAÇÃO DE SOFTWARE PEDAGÓGICO PARA A ALFABETIZAÇÃO DE ALUNOS PÚBLICO-ALVO DA EDUCAÇÃO ESPECIAL
Authors: Puzipe Papim Angelo Antonio
Published: September 2021

O processo de ensino e aprendizagem, realizado em salas de recursos multifuncionais, no cenário da educação especial, embora utilize as Tecnologias Digitais da Informação e Comunicação, não retira o papel de coadjuvante da interação e mediação sociocultural. O ser humano, indivíduo que ensina e que aprende, permanece no plano principal, administrando os instrumentos culturais adequados para promover o desenvolvimento sociocultural de alunos com deficiência intelectual, em processo de alfabetização. Em virtude disso, com o objetivo de compreender o processo de ensino e aprendizagem da linguagem escrita, empregando um software pedagógico na qualidade de mediador, realizou-se o estudo de caso de professores de educação especial, no ensino da linguagem escrita para alunos com deficiência intelectual. Trata-se de uma pesquisa qualitativa e descritiva, com base na análise causal da construção da linguagem escrita na ação e pensamento de alunos com deficiência intelectual. Conclui-se que o professor, através de indicativos de interação social, estabelece a qualidade do mediador e sua importância ao processo de ensino e aprendizagem.Palavras-chave: Software pedagógico. Educação especial. Alfabetização.
El comportamiento económico desde la perspectiva biológica y psicológica
Authors: Cifuentes Gómez Cindy , Delgado Ruiz Siervo Tulio , González Jorge Iván
Published: September 2021

El artículo explora algunos principios del comportamiento económico desde una aproximación biológica y sicológica, mediante un análisis reflexivo sobre la posibilidad de explicar las actuaciones económicas de los individuos a partir de la revisión de aspectos propios de disciplinas que están más allá de las fronteras de las ciencias económicas. Se destaca la importancia que tienen las emociones en la toma de decisiones. La comprensión de estas motivaciones ayuda a mejorar el diseño y la evaluación de las políticas públicas y las decisiones de inversión; además, se muestra que el contexto de desigualdad y felicidad incide en la formación del juicio heurístico.
Magnitud e implicaciones de la pobreza en Colombia
Authors: Vallejo Zamudio Luis E.
Published: September 2021

La pobreza es un concepto importante en ciencias sociales, cuya interpretación, por lo general, depende de la escuela de pensamiento en la que se sustenta. Sin embargo, la mayoría de sus estudiosos considera que la pobreza es la privación o deficiencia de una condición o la obtención de ingresos con relación a un umbral prefijado.
ENHANCING ENGLISH AS A FOREIGN LANGUAGE LEARNING IN UNDERGRADUATE STUDENTS: PERSPECTIVES AND STRATEGIES TO BEING BILINGUAL
Authors: Daza Hurtado Óscar Alejandro , Mosquera Ramírez Luis Carlos
Published: September 2021

El presente artículo es una reflexión a las perspectivas y estrategias para llegar a ser bilingüe, desde una exposición y postura de dos profesores nativos extranjeros a través del escenario de una conferencia virtual. El objetivo se enmarca en ampliar y generar maneras simples de interacción con el idioma extranjero a estudiantes de diferentes programas académicos de nivel profesional de la Universidad de Cundinamarca, quienes evidencian creencias y pensamientos que limitan el aprendizaje, lo que conlleva a una carencia en la puesta en práctica y presentan bajo resultado en las actividades que confluyen en las cuatro habilidades comunicativas del inglés. De esta manera, se implementa un método deductivo que, con la enunciación de experiencias vividas alrededor de aprender un idioma, ocasiona y permite crear una autonomía de mejora a futuro en el uso de la lengua para ser llevado a diferentes posibles escenarios de la vida cotidiana y profesional. Es así como, las conclusiones están dirigidas a una constancia autónoma en la implementación de acciones e interacción con elementos propios, incorporados o vinculados desde áreas de la tecnología, el arte, la ciencia o la sociedad.
FINDING TOPICS IN CREATIVE WRITING ON ENVIRONMENTAL PRESERVATION FOR BETTER TEACHING STRATEGIES: A CASE OF STUDY IN AN ELEMENTARY SCHOOL FROM COLOMBIA
Authors: Suárez Ballesteros Camilo Arturo , Bernal Camargo María Claudia Esperanza , Nidia Yaneth Torres Merchán
Published: September 2021

En esta investigación, se evaluaron ensayos sobre la preservación de árboles de estudiantes de cuarto grado (escuela primaria de Colombia) con Latent Dirichlet Allocation (LDA). El objetivo fue extraer los temas fundamentales, para comprender el comportamiento y la conciencia de los estudiantes hacia el medio ambiente a partir de la escritura creativa. Los resultados computacionales sugieren que las reflexiones del estudiante sobre la preservación del medio ambiente se centran en cinco temas principales en: Enseñar-Aprender a cuidar el medio ambiente, Explorar-descubrir el medio ambiente, Bienestar del medio ambiente, Preocupación por el medio ambiente y Restauración y conservación del entorno. Este análisis de texto por LDA puede complementar el análisis manual de los docentes, evitando el sesgo de veracidad y permitiendo potenciar las estrategias de enseñanza.
Is the Understanding Dementia Massive Open Online Course Accessible and Effective for Everyone? Native Versus Non-Native English Speakers
Authors: Kim Sarang , Bindoff Aidan , Farrow Maree , McInerney Fran , Borchard Jay , Doherty Kathleen
Published: September 2021

Most massive open online courses (MOOCs) are offered in English, including those offered by non-English speaking universities. The study investigated an identified English language dementia MOOC’s accessibility and effectiveness in improving the dementia knowledge of non-native English speaker participants. A total of 6,389 enrolees (age range 18–82 years; 88.4% female) from 67 countries was included in analyses. Dementia knowledge was measured by the Dementia Knowledge Assessment Scale (DKAS) before and after the MOOC completion. Rates of completion were also compared. Native English speakers (n = 5,320) were older, more likely to be female, less likely to be employed, and had lower educational attainment than non-native English speakers (n = 1025). Native English speakers were also more likely to care for or have cared for a family member or friend living with dementia than were non-native English speakers. Native English speakers had a significantly higher DKAS score both pre- (M = 33.0, SD = 9.3) and post-MOOC (M = 44.2, SD = 5.5) than did non-native English speakers (M = 31.7, SD = 9.1; and M = 40.7, SD = 7.7 for pre- and post-MOOC, respectively). Non-native English speakers with low pre-MOOC dementia knowledge scores gained significantly less dementia knowledge following course completion than did native English speakers (p <.001, adjusted for age and education). There was no significant difference between the two groups in their likelihood of completing the MOOC. Our findings suggest that non-native English speakers are motivated and able to complete the MOOC at similar rates to native English speakers, but the MOOC is a more effective educational intervention for native English speakers with low dementia knowledge.
Os paradigmas e princípios científicos da ciência da informação propostos por Le-Coadic
Authors: Maimone Giovana Deliberali , Silveira Naira Christofoletti
Published: August 2021

Apresenta os paradigmas e princípios científicos da Ciência da Informação relatados pelos estudos de Le Coadic, enfocando as relações desses com o uso da informação. Destaca-se ainda as linguagens documentárias como um importante recurso para a recuperação e uso da informação.
A nanoscale perspective on solid oxide and semiconductor membrane fuel cells: materials and technology
Authors: Zhu Bin , Mi Youquan , Xia Chen , Wang Baoyuan , Kim Jung-Sik , Lund Peter , Li Tao
Published: September 2021

Fuel cells could play an important role in the ongoing energy transition by providing clean and efficient energy conversion. Although the solid oxide fuel cell (SOFC) technology is a potential alternative for large-scale applications, its commercialization is limited by its electrolyte materials and has not yet been realized. Progress on new functional semiconductor-ionic materials (SIMs) and the fundamentals of SOFCs will provide new paths for their research and development. Herein, we discuss the nanoscale electrochemistry phenomena of SIMs in the context of new concepts for advanced SOFCs. A traditional SOFC consists of a three-layer anode/electrolyte/cathode structure, where the physically separated electrolyte layer is indispensable for ion transport to support the redox reaction and prevent the occurrence of short circuiting. A novel nano-SOFC concept is proposed to replace the traditional electrolyte by a SIM or semiconductor membrane and it can deliver superior performance, even at a lower temperature range (< 500 °C). The scientific basis and prospects of this new technological approach are presented and discussed.
Treatment patterns and a prognostic scoring system for elderly acute myeloid leukemia patients: a retrospective multicenter cohort study in China
Authors:   Department of Hematology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China, Zhang Chunli
Published: September 2021

Objective: Acute myeloid leukemia (AML) is primarily a malignant disorder affecting the elderly. We aimed to compare the outcomes of different treatment patterns in elderly AML patients and to propose a prognostic scoring system that could predict survival and aid therapeutic decisions. Methods: Patients aged ≥ 60 years who had been diagnosed with AML at 7 hospitals in China were enrolled (n = 228). Treatment patterns included standard chemotherapy, low intensity therapy, and best supportive care (BSC). Results: The early mortality rates were 31%, 6.8%, and 6.3% for the BSC, low intensity therapy, and standard chemotherapy groups, respectively. The complete remission rate of the standard chemotherapy group was higher than that of the low intensity therapy group. The median overall survival (OS) was 561 days and 222 days for the standard chemotherapy and low intensity therapy groups, respectively, and were both longer than that of the BSC group (86 days). Based on multivariate analyses, we defined a prognostic scoring system that enabled classification of patients into 3 risk groups, in an attempt to predict the OS of patients receiving chemotherapies and low intensity therapies. Low and intermediate risk patients benefited more from standard chemotherapies than from low intensity therapies. However, the median OS was comparable between standard chemotherapies and low intensity therapies in high risk patients. Conclusions: Our prognostic scoring system could predict survival and help select appropriate therapies for elderly AML patients. Standard chemotherapy is important for elderly AML patients, particularly for those categorized into low and intermediate risk groups.
Autorreporte de salud de los adultos mayores en México, 2012-2018
Authors: Lozano Keymolen Daniel , Gaxiola Robles Linares Sergio Cuauhtémoc , Martínez Espinosa Alejandro
Published: September 2021

El objetivo de esta investigación fue analizar los efectos de determinados factores sociodemográficos y de la salud en las trayectorias del autorreporte de salud de las personas mayores en México. Con datos del Estudio Nacional de Salud y Envejecimiento en México 2012-2018, se estimaron las trayectorias mediante modelos de estados latentes de Markov. Los resultados indican que, tanto en mujeres como en hombres hay tres trayectorias, las cuales fueron constantes incluso ajustando por variables sociodemográficas y de la salud. Sin embargo, el arreglo residencial, la multimorbilidad o los síntomas depresivos tuvieron efectos negativos sobre la probabilidad de un autorreporte de salud positivo. Estos resultados sugieren que, si bien debe profundizarse el análisis de los factores asociados con las trayectorias del autorreporte de salud, los arreglos residenciales, las múltiples enfermedades crónicas o la depresión tienen efectos longitudinales en la salud autoevaluada de los adultos mayores en México.
Pengaruh Penambahan Tepung Udang Rebon (Mysis relicta) Pada Pembuatan Kue Simping Terhadap Daya Terima Konsumen
Authors: Qori Nazzila  , Mahdiyah  , Sachriani
Published: September 2021

Penelitian ini bertujuan untuk mengetahui dan menganalisis pengaruh penambahan tepung udang rebon pada pembuatan kue simping terhadap daya terima konsumen berdasarkan aspek warna, rasa, aroma, dan tekstur. Penelitian ini dilakukan di Laboratorium Pengolahan Pastry dan Bakery Program Studi Pendidkan Tata Boga Universitas Negeri Jakarta. Dengan waktu penelitian dimulai pada bulan Mei 2019 hingga Januari 2020. Metode yang digunakan adalah metode eksperimen. Sampel pada penelitian ini adalah kue simping dengan penambahan tepung udang rebon sebanyak 6%, 9%, dan 12% kemudian diujikan kepada 30 panelis agak terlatih yang menilai keseluruh aspek. Berdasarkan hasil uji hipotesis dengan menggunakan uji Friedman dan uji lanjutan Tuckey menunjukan adanya pengaruh penambahan tepung udang rebon terhadap peningkatan daya terima kue simping pada aspek warna, rasa, dan aroma. Sedangkan pada aspek tekstur tidak terdapat pengaruh. Kesimpulan hasil penilaian organoleptik secara umum dari semua aspek bahwa kue simping dengan penambahan tepung udang rebon yang paling disukai oleh konsumen adalah kue simping dengan persentase penambahan 9%.
Buku Ajar Al-Islam Dan Kemuhammadiyahan – 4 (AIK - 4)
Authors:   Mu‘adz, Astutik Anita Puji
Published: September 2021

Syukur Alhamdulillah kami haturkan kehadirat Allah SWT yang telah memberi rahmat dan karuniaNya, sehingga penulis dapat menyelesaikan buku ajar di Fakultas Ilmu Sosial dan Ilmu Politik dengan judul “Islam dan Ilmu Pengetahuan (AIK IV)”. Buku ini dimaksudkan sebagai pedoman perkuliahan AIK dalam Ilmu Sosial dan Ilmu Politik agar pendidikan AIK dapat berlangsung sesuai dengan tujuan yang diharapkan baik standart kompetensi, isi, proses dan evaluasi.Bagian awal dari buku ajar ini memuat pengembangan IPTEKS dalam dunia Islam yang diperdalam dengan pembahasan mengenai Ilmu Sosial dan Ilmu Politik dalam Islam. Dengan harapan agar mahasiswa mampu menguasai dan mengintegrasikan nilai-nilai Islam dalam pengembangan dan penerapan Ilmupengetahuan terutama bidang Sosial danPolitik. Ucapan terima kasih kami sampaikan kepada Pimpinan Universitas Muhammadiyah Sidoarjo yang telah memberikan kesempatan kepada penulis dan berbagai pihak yang telah membantu terselesaikannya buku ajar ini. Saran dan sumbangsih pemikiran sangat kami harapkan dari seluruh dosen pengampu AIK demi kesempurnaan dan perbaikan selanjutnya. Akhirnya, semoga kehadiran buku ajar ini bermanfaat demi peningkatan mutu Pendidikan Al-Islam dan Kemuhammadiyahan di Perguruan Tinggi Muhammadiyah
Survey of Musculoskeletal Injuries among Female Bharatanatyam Dancers in the Udupi District of India
Authors: Kumar Lavanya P , Shenoy Shruti J
Published: September 2021

BACKGROUND: Bharatanatyam is an Indian classical dance form that is practiced globally. There is limited information about the prevalence of injuries in Bharatanatyam dancers. OBJECTIVES: To investigate the prevalence of musculoskeletal injuries and specifics of dance training in female
Bharatanatyam dancers in the Udupi district of India. METHODS: We developed and tested a survey for Bharatanatyam dancers regarding injury history in the prior year, including location, time loss, cause, and need for medical help. We also obtained demographic and training information. RESULTS:
101 dancers completed the survey. 10.8% of dancers reported musculoskeletal injuries because of participation in dance. They sustained 0.65 injuries/1,000 hours of dancing. The most frequently injured areas were ankle (27.2%) and knee (27.2%) followed by lower back (13.6%) and hip (9%). Despite
being injured, 36.4% of the dancers continued to dance. 54.5% of the injured dancers sought the help of a medical professional for their dance-related injuries. The most common surface for dance was concrete followed by other hard surfaces such as marble and tile. CONCLUSION: Female Bharatanatyam
dancers are prone to injuries of the lower extremity and back. Most dancers in our study practice the Pandanalluru style on hard surfaces. There is a need to investigate the impact of training factors on the injury occurrence.
ADVANCEMENT AND SETBACK IN ISLAMIC BANKING PRODUCTIVITY IN ASEAN: DO TECHNOLOGICAL CHANGES MATTER?
Authors: Rusydiana Aam Slamet , Assalafiyah Aisyah
Published: September 2021

This study applies the Banker, Charnes and Cooper (BCC) model as a basic approach to the data envelopment analysis used to measure the level of productivity of 24 Islamic banks in four ASEAN countries (Indonesia, Malaysia, Brunei Darussalam and Thailand) over the 2010-2019 period. The Malmquist index was also employed, which is intended to accommodate improvements in efficiency, together with advancementsin technology. According to the Malmquist index scores on total factor productivity (TFP) change, 17 of the 24 Islamic banks (or 70.8 percent) achieved an improvement in productivity over the research period, with Thailand recording the highest productivity level increase. Overall, the most productive Islamic bank was Affin Islamic Bank Berhad. Finally, it was observed that there was a productivity growth in the last two years of the period, namely 2017-2018 and 2018-2019. The productivity change was driven more by efficiency than by technology, implying that Islamic banks in ASEAN countries must improve this aspect.
SAY NO TO INFLATION TARGETING: A CALL FOR THE ADAPTATION OF A ZERO-INTEREST REGIME
Authors: Rehman Atiq Ur
Published: September 2021

In its early history, monetary policy focused on numerous objectives, including stable growth, full employment, stable exchange rates and price stability. In the 1990s, many countries shifted their monetary policy framework from monetary aggregate/interest rate targeting to inflation targeting, in which inflation was regarded as the primary target of monetary policy, and interest rates the primary tool for achieving target inflation. Inflation targeting has diverted the focus of central banks from growth and employment to price stability. Unfortunately, there is considerable evidence which shows that inflation targeting frameworks are unable to control inflation in the way central banks want, and in fact lead to a greater departure from optimal growth and employment, the two key targets of sustainable development goals (SDGs). There is also evidence suggesting a strong association between inflation targeting and the move away from several other SDGs. Employing a systematic review of the related literature and Granger causality tests applied to data from various countries, this paper shows that inflation targeting fails to control inflation and has several undesirable impacts on a wide range of socioeconomic indicators. It is argued that the zero-interest regime is the optimal regime with respect to the impact on socioeconomic indicators, and also supports the interest free economy advocated by Islam.
Oficina de construção de cisterna em ferrocimento no IFPR Campus Cascavel
Authors: Cosmann Natássia , Orvatti Lilian
Published: August 2021

O aproveitamento da água da chuva para a irrigação de olerícolas é uma opção ambientalmente saudável e segura. Existem diversos modelos de reservatórios de águas pluviais, incluindo tecnologias de construção de fácil acesso e execução. Esta proposta objetivou oferecer uma oficina de construção de cisterna do tipo ferrocimento para implementar a captação da água da chuva no Instituto Federal do Paraná (IFPR) Campus Cascavel, a fim de irrigar a horta sem agrotóxicos da instituição. Foi construída uma cisterna de 4000 litros, moldada com tela de arame e com paredes de cimento. A água captada do telhado do ginásio de esportes é deslocada para a cisterna e a irrigação da horta ocorre por gravidade. Durante a oficina, foi possível transmitir aos participantes a sequência das etapas que devem ser seguidas para a obtenção do reservatório, propiciando o manejo dos materiais empregados, a prática da construção e promovendo discussões acerca da importância da conservação da água. Foi possível constatar o envolvimento de todos os inscritos, com depoimentos de planejamento de replicação do método em outros espaços. A proposta atendeu aos objetivos educativos e de transformação social, bem como contribuiu para a sustentabilidade ao fomentar a formação de multiplicadores da tecnologia e do conhecimento empregados.
A desigualdade social e a educação no Brasil: uma revisão de literatura
Authors: Vendrami Leandro , Oliveira Fatima , Tyeko Anami Karin
Published: August 2021

O propósito deste artigo é apresentar e discutir compreensões de estudos com a temática referente a desigualdade social e seu reflexo no campo educacional, alicerçados na literatura clássica, com concepções de sociólogos como Pierre Bourdieu, com o objetivo de apresentar aos profissionais da educação, as reflexões desses pesquisadores. A abordagem metodológica usada foi qualitativa e bibliográfica, e por ser um tema contemporâneo e amplamente discutido, este estudo abarcou uma revisão bibliográfica, a partir de artigos encontrados nas plataformas SciELO e Google Scholar abrangendo: a desigualdade social e a educação no Brasil, com um recorte temporal entre os anos de 2020 e 2021. As informações produzidas nesta revisão de literatura são relevantes para a verificação da produção acadêmica e a abrangência de teorias e reflexões dos pesquisadores com o propósito de compreender as desigualdades sociais e a educação sob diferentes olhares. Foram encontrados 07 artigos que nos trazem aspectos da desigualdade social e o seu reflexo na educação, os quais nos revelam que as políticas públicas isoladas não revertem o quadro de desigualdades sociais no campo educacional.
Antagonistic cell surface and intracellular auxin signalling regulate plasma membrane H+-fluxes for root growth
Authors: Li Lanxin , Verstraeten Inge , Roosjen Mark , Takahashi Koji , Rodriguez Lesia , Merrin Jack , Chen Jian , Shabala Lana , Smet Wouter , Ren Hong , Vanneste Steffen , Shabala Sergey , De Rybel Bert , Weijers Dolf , Kinoshita Toshinori , Gray William M. , Friml Jiří
Published: September 2021

Growth regulation tailors plant development to its environment. A showcase is response to gravity, where shoots bend up and roots down1. This paradox is based on opposite effects of the phytohormone auxin, which promotes cell expansion in shoots, while inhibiting it in roots via a yet unknown cellular mechanism2. Here, by combining microfluidics, live imaging, genetic engineering and phospho-proteomics in Arabidopsis thaliana, we advance our understanding how auxin inhibits root growth. We show that auxin activates two distinct, antagonistically acting signalling pathways that converge on the rapid regulation of the apoplastic pH, a causative growth determinant. Cell surface-based TRANSMEMBRANE KINASE1 (TMK1) interacts with and mediates phosphorylation and activation of plasma membrane H+-ATPases for apoplast acidification, while intracellular canonical auxin signalling promotes net cellular H+-influx, causing apoplast alkalinisation. The simultaneous activation of these two counteracting mechanisms poises the root for a rapid, fine-tuned growth modulation while navigating complex soil environment.
Does Health Service Funding Go Where the Need Is? A Prototype Spatial Access Analysis for New Urban Contracts Data
Authors: Koschinsky Julia , Marwell Nicole , Mansour Raed
Published: September 2021

Background | Much of spatial access research measures the proximity to health service locations. We advance this research by focusing on whether health service funding is within walkable reach of neighborhoods with high hardship. This is made possible by a new administrative data source: financial contracts data for those human services that are delivered by nonprofits under contract with the government.Methods | In a prototypical spatial access study we apply a classic 2-step floating area catchment model for walkable network access to analyze 2018 data about contracted nonprofit health services funded by the Chicago Department of Public Health (CDPH). CDPH collected the data for the purpose of this study.Results | We find that the common container approach of aggregating contract amounts by provider headquarter locations in a given area (ignoring satellite service sites) underestimates the share of funding that goes to Chicago neighborhoods with higher hardship. Once service sites and spatial access are taken into account, a larger share of CDPH funds was found to be within walkable reach of Chicago’s high hardship areas. This was followed by low hardship areas (which could be driven by more headquarter locations there that do serve areas throughout thecity). Medium hardship areas trail both, perhaps warranting closer attention. We explore these results by program type and neighborhood with a spatial decision support system developed for the health department.Conclusions | The typical approach for analyzing human service contracts based on headquarters is misleading -- in fact, we find that results are reversed when service sites and walkable access are taken into account. This prototype provides an alternative framework for avoiding these misleading results.
Xihuang Pill Inhibits The Development of DMBA Combined With Oestrogen- And Progesterone-Induced Precancerous Breast lesions In Rats By The PI3K/AKT/mTOR Signaling Pathway
Authors: Li De-hui , Fan Huan-fang , Guo Na , Sun Chun-xia , Dong Jing-fei , Su Yi-fan , Gu Yi-ting , Liu Jiao
Published: September 2021

Background:To study the inhibitory effect of Xihuang pill on the development of DMBA combined with oestrogen- and progesterone-induced breast precancerous lesions in rats by the PI3K/AKT/mTOR signaling pathway and to explore the effect of Xihuang pill in preventing and treating breast cancer. Method: Establishment of a rat model of precancerous breast lesions with DMBA combined with oestrogen and progesterone sequential induction for 10 weeks. Xihuang pill was administered continuously by gavage for 4 weeks. Rat breast tissue was stained with haematoxylin-eosin (HE). The pathomorphological changes were observed with a light microscope. TUNEL staining was used to detect cell apoptosis in breast tissue. Western blotting was used to detect the protein expression of P-PI3K, P-AKT (S473), P-AKT (T308), PTEN, P-tuberin/TSC2, P-tuberin (p-S939), p-mTOR, and P-4E-BP1 in breast tissues. qRT-PCR was used to detect the gene expression of PTEN mRNA and VEGF mRNA. Immunohistochemistry was used to detect the protein expression of P-S6, p-p70s6k and VEGF.Result:Compared with the disease model group, the low-, middle- and high-dose Xihuang pill groups could significantly reduce the degree of breast pathology, and the number of apoptotic precancerous breast lesion cells increased with increasing Xihuang pill dose. The expression levels of P-PI3K, P-AKT (S473), P-AKT (T308), p-mTOR, P-4E-BP1, p-S6, p-p70S6K, VEGF protein and VEGF mRNA dropped with increasing Xihuang pill dose. The expression levels of PTEN, P-tuberin/TSC2, P-tuberin (p-S939) protein and PTEN mRNA increased with increasing Xihuang pill dose. Conclusion:Xihuang pill can promote the apoptosis of precancerous breast lesion cells, reduce the proliferation of vascular endothelial cells, and then inhibit the progression of precancerous breast lesions. Its mechanism is probably associated with the regulation of the PI3K/AKT/mTOR pathway related protein expression.
Non-Hermitian Electronics Multipods of Electromagnetically Induced Transparency (EIT) and Absorption (EIA)
Authors: TAGOUEGNI Senghor , FOTSA-NGAFFO Fernande , KENFACK-JIOTSA Aurélien
Published: September 2021

We study a non-Hermitian electronic dimers system based on an imaginary resistor (Z) in a (N+2) level atomic multi-pod configuration. Non-Hermitian systems depend on a gain/loss parameter and are specifically marked by a degeneracy exhibited at an exceptional point (EP) separating different phases of complex modes dynamics. Interestingly, the structural characterization and the dispersive properties reveal a broad range of strong coupling where the interplay between the control and the probe field induce a simultaneous EIT, EIA and ATS. Here, by identifying the underlying physical mechanisms, we show that multiple windows of transparency can be strongly enhanced by the incorporation of several dimers in the multipod network. On the other hand, if the pumping field is resonant in the weak regime, multiple EIT and EIA windows result in the number of dimers. Remarkably, the proposed system embedded a multiple coupling mechanism whose modulation induces a couplingless point whereby the energy cross. At this point EIT and related phenomena vanish.
MicroRNA Expression in Circulating Leukocytes and Bioinformatic Analysis of Patients with Moyamoya Disease
Authors: Kang Kaijiang , Shen Yuan , Zhang Qian , Lu Jingjing , Ju Yi , Ji Ruijun , Li Na , Wu Jianwei , Yang Bo , Lin Jinxi , Liang Xianhong , Zhang Dong , Zhao Xingquan
Published: September 2021

Background and purpose- MicroRNAs (miRNAs) in exosomes had been implicated differentially expressed in MMD patients, but the miRNAs expression in circulating leukocytes remains unclear. This study was investigated on the differential expression of miRNAs in peripheral leukocytes between MMD patients and healthy adults, and among patients with subtypes of MMD.Methods- A total of 30 patients with MMD and 10 healthy adults were enrolled in a stroke center from October 2017 to December 2018. The gene microarray was used to detect the differential expression profiles of miRNA in leukocytes between MMD patients and controls, and the differentially expressed miRNAs were verified by the method of real-time PCR. The Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) were used to explore the key signaling pathways and possible pathogenesis of MMD.Results- The microarray results showed 12 differentially expressed miRNAs in leukocytes of MMD patients compared with controls (fold change > 2.0 and P < 0.05), of which 7 miRNAs were up-regulated (miRNA-142-5p, miRNA-29b-3p, miRNA-424-5p, MiRNA-582-5p, miRNA-6807-5p, miRNA-142-3p, miRNA-340-5p), and 5 miRNAs were down-regulated (miRNA-144-3p, miRNA-144-5p, miRNA-451a, miRNA-486-5p, miRNA-363-3p). The real-time PCR confirmed 7 differentially expressed miRNAs (P<0.05), of which 4 miRNAs (miRNA-29b-3p, miRNA-142-3p, miRNA-340-5p, miRNA-582-5p) were up-regulated, and 3 miRNAs (miRNA-363-3p, miRNA-451a and miRNA-486-5p) were down-regulated. Both GO and KEGG analysis suggested that the Wnt signaling pathway may be involved in the pathogenesis of MMD. In addition, miRNAs were also differentially expressed among patients with subtypes of MMD. Conclusion- This study indicated that miRNAs are differentially expressed in peripheral leukocytes between MMD patients and healthy adults, and among patients with subtypes of MMD. The Wnt signaling pathway is probably involved in the pathogenesis of MMD.
Therapeutic Potential of miR-29a in Breast Cancer Patients with type 2 Diabetes and its Regulatory Mechanism
Authors: li zhihua , Hu Yang-yang , Luan Wen-jing , Li Cong , Xiong Qiu-yun , Huang Kedi , Min Liangliang , cheng Lu
Published: September 2021

MicroRNAs (miRNAs) acting as tumour suppressors or oncogenes (oncomiRs), are a promising new focus of targeted therapeutics for cancer. Diabetes preexisted in approximately 16% of breast cancer patients. This study mainly aims to investigate the therapeutic potential of miR-29a in breast cancer patients with type 2 diabetes (BDM) and its regulatory mechanism. Our results indicated that miR-29a is upregulated in BDM patients, which was correlated with worse prognosis. In human breast cancer cells, miR-29a knockdown reduced cell proliferation, cells migration and invasion in BDM conditions (25 mmol/L glucose + 25 nmol/L insulin). In xenograft mouse model for BDM, miR-29a knockdown suppresses MDA-MB-231 cells tumourigenesis and metastasis. Finally,we demonstrated that miR-29a promoted cell growth and metastasis of BDM via targeting of SIRT1.Collectively, our findings indicated that anti-miR-29a inhibited cell proliferation and invasion in BDM by targeted SIRT1, anti-miR-29a may represent a novel therapeutic approach for the management of BDM patients.
Factors of Dental Hygienists' Experiences Related to the Elderly that Affect the Perception of Human Rights Violations Against the Elderly: A Cross Sectional Study
Authors: Jang Kyeung-Ae , Kim Yu-Rin
Published: September 2021

Background: Korean society has become an elderly society at an unprecedented rate, and the social and economic problems emerging in such a society are very serious. Good oral health is important for older people’s wellbeing and quality of life, and is essential for healthy ageing. Therefore, the purpose of this study is to examine the effect of the elderly-related experiences of dental hygienists in charge of oral health on human rights violations against the elderly. Methods: This study was conducted through an IRB review at Silla University in Korea (No. 1041449-202012-HR-001). For about a month from February 1, 2021, the survey questionnaire was distributed to dental hygienists living in South Korea, and 153 people who accomplished and sent back the questionnaires were selected as the final subjects. Polyserial correlation analysis was performed to confirm the relevance of each factor, and multiple regression analysis was performed to identify the factors of elderly-related experiences that affect the perception of human rights violations against the elderly.Results: All three experiences related to the elderly were highly related to the perception of violations of financial human rights of the elderly (p<0.01). In addition, the experience of education related to the elderly showed a high perception of psychological violation of the human rights of the elderly (R=0.405, p<0.01), and the experience of volunteer activities related to the elderly showed a high perception of neglectful violations of human rights of the elderly (R=0.277, p<0.01). Conclusion: At this point in time when the number of the elderly is increasing, dental hygienists have to focus on specialized oral health management for the elderly that respects their human rights.
Interferon Regulatory Factor-1 Regulates Cisplatin-Induced Apoptosis and Autophagy in A549 Lung Cancer Cells
Authors: zhang lemeng , Cheng Tianli , Yang Hua , Chen Jianhua , Wen Xiaoping , Jiang Zhou , Yi Huihuang , Luo Yongzhong
Published: September 2021

Purpose: This study aimed to investigate the expression and function of interferon regulatory factor-1 (IRF-1) in non-small cell lung cancer (NSCLC). Methods: IRF-1 expression and its prognostic value were investigated through bioinformatic analysis. The protein expression levels of IRF-1, cleaved caspase-3, and LC3-I/II were analyzed by western blotting. A lentiviral vector was used to overexpress or knockdown IRF-1 in vitro. Mitochondrial membrane potential (MMP) and reactive oxygen species (ROS) were analyzed by JC-1 and DCFH-DA staining, respectively. ATP, SOD, MDA, cell viability, LDH release, and caspase-3 activity were evaluated using commercial kits. Results: Compared to the levels in normal tissues, IRF-1 expression was significantly lower in lung cancer tissues and was a prognostic factor for NSCLC. Cisplatin treatment induced IRF-1 activation, ROS production, ATP depletion, SOD consumption, and MDA accumulation in A549 lung cancer cells. IRF-1 overexpression promoted mitochondrial depolarization, oxidative stress, and apoptotic cell death and inhibited autophagy in A549 cells, and these effects could be reversed by IRF-1 knockdown. Conclusion: These data suggest that IRF-1 regulates apoptosis, autophagy and oxidative stress, which might be served as a potential target for increasing chemotherapy sensitivity of lung cancer.