bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengaruh Penyuluhan Gizi Seimbang Terhadap Pengetahuan dan Sikap Masyarakat Selama New Normal didesa Temmappaduae Kecamatan Marussu Kabupaten. Maros 2020
Authors: Villda Nuraini Ade Saputri  , Musdalifah  , Nur Nikmah Siradjuddin  , Suherman  , H. Syafruddin
Published: August 2021

In nutrition science known five kinds of nutrients, namely carbohydrates, fats, proteins, minerals, and vitamins. The purpose of this research aims to know the influence of balanced nutrition counseling on knowledge and attitudes in the community during the new normal in the village temmappaduae District Marussu Maros district. This type of research using Quasi Experimental design of this study using Pretest Group Design Posttest observations were conducted at the beginning (pretest) and end of activity (posstest). The rate of change in respondents was seen by comparing the pretest results with the posstest. The population in this study was the community in Sinar Griya Cendana Housing, as many as 250 families and sampling techniques using purposive sampling techniques. Measurements are performed using questionnaire sheets. The results showed that there was an increase in knowledge and attitude of balanced nutrition counseling before and after being given balanced nutrition counseling. Wilcoxon Signed Ranks Test statistical test results show that balanced nutrition counseling has a significant influence on the knowledge and attitude of balanced nutrition counseling in the community of sandalwood rays aimed at results (p<0.05). Based on these results, it can be concluded that there is an influence of balanced nutrition counseling on the knowledge and attitudes of the community during the new normal in dessa temmappaduae Marussu Subdistrict Maros. ABSTRAK Dalam ilmu gizi dikenal lima macam zat gizi, yaitu karbohidrat, lemak, protein, mineral, dan vitamin. Tujuan Penelitian ini bertujuan untuk mengetahui pengaruh penyuluhan gizi seimbang terhadap pengetahuan dan sikap pada masyarakat selama new normal di desa temmappaduae kecamatan Marussu kabupaten Maros. Jenis penelitian ini menggunakan Quasi Eksperiment desain penelitian ini menggunakan Desain Grup Pretest Posttest observasi dilakukan pada awal (pretest) dan akhir kegiata (posstest). Tingkat perubahan responden dilihat dengan membandingkan antara hasil pretest dengan posstest. Populasi pada penelitian ini adalah masyarakat di Perumahan Sinar Griya Cendana, sebanyak 250 kk dan teknik pengambilan sampel menggunakan teknik purposive sampling. Pengukuran dilakukan menggunakan lembar kuesioner. Hasil penelitian menunjukkan bahwa terjadi peningkatan pengetahuan dan sikap penyuluhan gizi seimbang sebelum dan sesudah diberikan penyuluhan gizi seimbang. Hasil uji statistik Wilcoxon Signed Ranks Test menunjukkan bahwa penyuluhan gizi seimbang memiliki pengaruh yang signifikan terhadap pengetahuan dan sikap penyuluhan gizi seimbang pada masyarakat sinar griya cendana yang ditujukan dengan hasil (p<0,05). Berdasarkan hasil tersebut, dapat disimpulkan bahwa terdapat pengaruh penyuluhan gizi seimbang terhadap pengetahuan dan sikap masyarakat selama new normal di dessa temmappaduae Kecamatan Marussu Kabupaten Maros.
Spatial-temporal Patterns of MODIS Active Fire/Hotspots in Chiang Rai, Upper Northern Thailand and the Greater Mekong Subregion Countries During 2003-2015
Authors: Chart-asa Chidsanuphong
Published: August 2021

For the past decade, smoke-haze pollution from forest fires and open burning has been a yearly recurring problem over Chiang Rai and other provinces in Upper Northern Thailand, along with other countries in the Greater Mekong Sub-region. Remote-sensing active fire/ hotspot data are currently used for monitoring the forest fires and open burning in the sub-region. This study aimed to extend the current monitoring work by performing spatial and temporal analysis to examine the patterns, either globally or locally, of MODIS active fires/hotspots during the critical smoke-haze pollution periods from January to April in 2003-2015. Fire radiative power was used as a weight attribute for each active fire/hotspot. Administrative unit maps were used for aggregating data and creating spatial weight matrices. Results indicated that for all the years over the investigated period and based on detected locations, active fires/hotspots were overall clustered spatially across provincial, interprovincial, and international scales. Their density patterns were locally variable for each year, but the high concentrated zones, in terms of both fire counts and fire radiative powers, were consistently bounded in the hilly and mountainous areas, confirming that the forest fires and open burning problem keeps recurring in certain areas. When aggregated by administrative unit, the administrative boundaries with high active fires/hotspots, in terms of both fire counts and fire radiative powers, were spatially clustered, either globally or locally, but there was only an increasing trend of the clustering intensity in fire radiative powers, implying that the forest fires and open burning problem have become more severe in particular areas. These findings could be useful for further reviewing and strengthening current measures and plans of fire and smoke haze pollution management.
Metástasis coroidea como primera manifestación de carcinoma primario de pulmón
Authors: Zepeda Maria , Uribe Patricia , Méndez Gustavo
Published: August 2021

La metástasis coroidea es el tumor intraocular más común en adultos. Estudios de autopsias sugieren que aproximadamente el 10% de pacientes con cáncer diseminado tiene metástasis ocular, más frecuentemente a la coroides. Presentamos el caso de una mujer de 37 años de edad quien consultó por disminución de la agudeza visual a consecuencia de una metástasis coroidea.
Sebaceoma y Síndrome de Muir Torre
Authors: Orantes Ana , Gramajo Marisol
Published: August 2021

El sebaceoma es una neoplasia benigna, papulonodular, amarillenta, que suele aparecer en rostro, piel cabelluda o en áreas con abundantes glándulas sebáceas.  Se ha descrito en la literatura la asociación de neoplasias sebáceas con el síndrome de Muir Torre. Se presenta el caso de un paciente masculino con antecedente de cáncer de colon y presencia de lesión cutánea única en tórax, dos años después del primer diagnóstico.
Enfermedad Pulmonar Quística Idiopática
Authors: Herwig Kimberly , Palma Maynor , Torres Servio , De-León Juan
Published: August 2021

Las Enfermedades Pulmonares Quísticas incluyen un grupo heterogéneo de patologías con múltiples causas. La presentación clínica es variable y generalmente incluye disnea progresiva, tos y opresión torácica. El diagnóstico suele ser difícil. La tomografía torácica de alta resolución juega un rol esencial. El tratamiento depende de la causa primaria, sin embargo, en algunos casos, ésta no se puede determinar. Presentamos el caso de una mujer de 45 años con enfermedad pulmonar quística idiopática.
Dermatofitosis generalizada por trichophyton rubrum
Authors: Chang Patricia , Madrid Francia , Logemann Heidi
Published: August 2021

Se presenta el caso de una paciente de 68 años de edad, con una dermatofitosis generalizada por Trichophyton rubrum de 1 año de evolución y buena respuesta al tratamiento
Species of sucking pests of ornamental crops in the conditions of the Southern Coast of the Crimea
Authors: Trikoz N. N. , Andreev R. O. , Shevtsov S. I.
Published: August 2021

The results of the analysis of the species composition of sucking pests species during the period from 2009 to 2019 are presented. Based on long-term phytosanitary monitoring, 37 species belonging to 12 families were identified, of which the most numerous are the families Diaspididae and Aphididae of the order Hemiptera. According to the nature of trophic connections, 59.9% are monophages, 32.4% are polyphages and 8.1% are oligophages. According to the nature of the damage caused, sucking species differ from each other. Some species lead to a change in the color of leaves and flowers (thrips, mites, coccids), others cause deformation of the leaf blade and inflorescences (coccids, worms, false coccids, herbivorous mites) and the third group includes species that form galls on the leaves (laurel psyllid, pistachio marginal gall aphid). According to ecological features, sucking pest species are divided into three main groups: open-living species, which include aphids, cicadae, psyllas, white flies, the second group includes species that have covers of various nature on the body, such as coccids, worms and false coccids, and the third group consists of gall makers. The dominant species, the degree of harmfulness, the frequency of occurrence and the range of forage plants were determined.
Fruit formation of the distylous species Jasminum fruticans L. (Oleaceae)
Authors: Kuzmina T. N.
Published: August 2021

The article presents the results of a comparative analysis of the fruit formation of long-styled and short-styled plants Jasminum fruticans L. (Oleaceae). The long-styled flowers have larger ovaries and ovules than short-styled ones. Visual signs of degeneration and reduction of the structures of the ovules were not detected. At the same time, the morphs of J. fruticans differ in fruit formation. The proportion of dimeric fruits with two seeds is greater in long-styled plants. Three periods of abortion of fruits/seeds were identified: (1) 1-7 days after flowering correspond to the stage of pollination and fertilization; (2) 8-14 days are the proembryonic stage of embryogenesis; (3) 15-35 days are the stage of globular embryo. The periods of fruits abortion are the same for long- and short-styled plants. Statically significant difference between morph was revealed in the first period of abortion. Differences in morphs of fruits formation indicate less effective pollination and fertilization in short-styled plans. The fruits of J. fruticans mature three months after flowering.
Antecological features of Rubus odoratus L. during introduction in the North
Authors: Miftakhova S. A.
Published: August 2021

The article describes the peculiarities of flowering and pollination of an introduced sample of Rubus odoratus in the conditions of the North (Komi Republic). Experiments on controlled pollination have shown that the species is characterized by xenogamy, although there was also idiogamy. The fruits formed through idiogamy had many voids between the drupes, often did not reach maturity, and the seeds were dissimilar. Dichogamy in the form of protandria and partial hercogamy are not an obstacle, but only additional factors that prevent self-pollination. The probable cause of self-sterility is self-incompatibility. R. odoratus has no specific pollination strategy. The main method of pollination of the species is entomophilia, carried out by pollinating insects mainly representatives of three orders: Coleoptera, Diptera and Hymenoptera. R. odoratus is characterized by visual and olfactory attraction.
SPECTRAL TECHNIQUE FOR COMPLEX PROCESSING OF AEROSPACE
MONITORING MULTISPECTRAL VIDEO DATA
Authors: Vasilevsky V. V.
Published: August 2021

The article studies the problem of increasing the efficiency of aerospace monitoring in identification of low-observable objects on the earth’s surface. The model of multispectral images based on spatial harmonic components is proposed. The article describes the algorithm of complex adaptive processing and image synthesis designed to improve identification of low-observable surface objects.
SOLDER SEALING of CONNECTORS IN SOLID-STATE MICROWAVE
MODULES. PROBLEMS AND SOLUTIONS
Authors: Sonevitskiy A. S. , Zhukov V. S.
Published: August 2021

This article presents the study of a promising technology utilizing the tin-lead solder for the sealing of current-transmitting components of modern solid-state microwave modules: connectors, leads and others. This technology was developed and implemented at the S&PE Pulsar JSC. The article highlights the advantages and disadvantages of the technique, presents the diagrams of the structures used.
COVID-19 and Dengue: A potentially emerging healthcare challenge for Pakistan
Authors: Raza Faiz Ahmed
Published: August 2021

Pakistan is facing the third wave of the SARS-CoV-2 pandemic and could head towards the fourth one. Although the burden of COVID-19 remained significantly low in the country as compared to its neighboring countries despite similar gene pool, health system, and climatic conditions, still Pakistan has dealt with the disease with relative effectiveness. The pandemic imposed immense pressure on the public health systems due to increased demand for specialized isolation wards and intensive care units and disease-related morbidity and mortality. Many of the tertiary care hospitals in the major pandemic-stricken districts have been transformed into specialized centers dedicated to the treatment of COVID-19. This resulted in diverting major hospital resources and manpower to deal with the pandemic at the cost of other medical and surgical conditions. A recent pulse survey conducted by World Health Organization (WHO) in 135 countries demonstrated that the SARS-CoV-2 pandemic severely affected the global health services, while services for endemic tropical diseases (like dengue) were affected in 44% of countries, especially in resource-limited countries. Moreover, large-scale community-based interventions including vector surveillance and control were disrupted in 60% of the countries.1 Another survey by WHO on malaria control in sub-Saharan Africa demonstrated a >20% increase in malaria cases and a doubling of malaria-associated deaths due to a decline in malaria control activities during the pandemic. It is expected that the future catastrophe due to malaria might be much greater than the COVID-19 in endemic regions. Therefore, WHO recommends continuous monitoring, surveillance, and treatment to control the spread of malaria.2
Maternal and fetal factors contributing to neonatal outcome in Al-Tibri Medical College and Hospital
Authors: Saboohi Erum , Seema Nighat , Hassan Abdulah Hadi
Published: August 2021

Background: The study was done to identify the maternal and fetal factors contributing to neonatal outcome and to evaluate the correlation between risk factors and adverse neonatal outcome.

Subjects and methods: This prospective observational study was conducted on 126 mothers and their neonates fulfilling the selection criteria at Al-Tibri Medical College and Hospital. A self-designed Performa was used to enter data of subjects. Sick neonates were referred to neonatal intensive care unit for admission and management. The results were analyzed by using SPSS version 22. A p-values <0.05 was considered as significant.

Results: Out of 126 enrolled subjects, 81% mothers were multigravidas, 31% were unbooked, 13.5% had gestational comorbidities, 15% were drug addict, 2% were Hepatitis B positive. 22.2% underwent emergency LSCS while 31.7% delivered babies by elective LSCS. Regarding fetal factors contributing to sick babies, IUGR (20%), twin fetuses (15.4%), prematurity (47.7%) were significant. 65 were sick babies. Adverse neonatal outcomes observed were prematurity in 25.4%, IUGR in 11.1%, NICU admission in 33.3%, and neonatal death in 2%. Risk factors associated with adverse neonatal outcomes were positive maternal drug addiction (p-value = 0.028), preterm delivery (p-value<0.001), NICU admission (p-value<0.001) and low birth weight (p-value <0.001).

Conclusion: Compromised maternal antenatal care has profound deleterious effect on fetus and neonate. Obstetricians, perinatologists and neonatologists need to work in concord to improve maternal antenatal care hence improving neonatal outcome. In our study adverse neonatal outcome was associated with unbooked cases, delivery by EmLSCS, addicted mother, preterm delivery, LBW and neonates requiring NICU admission.
Prevalence of insomnia and anxiety in university students during the COVID-19 lockdown: A cross-sectional study
Authors: Mahmood-ul-Hassan Ameer Hamza , Sannan Abdul , Nooz Nehala , Ramay Ansa , Huzaifa Muhammad , Zaidi Syed Muhammad Jawad , Mahmood-ul-Hassan Ayesha
Published: August 2021

Background: The world is facing COVID-19 pandemic and almost 70% of the world had gone under Lockdown. People are facing stress, insomnia and anxiety. The lack of basic awareness and spread of fake news are common causes of all these issues. This study was done to determine the prevalence of insomnia and anxiety in medical and non-medical students.

Subjects and methods: Subjects were approached through friends in universities using WhatsApp. People having insomnia and anxiety before quarantine were excluded from this study. People using anti-depressants and anti-psychotics before quarantine were also excluded from this study. A descriptive cross-sectional study was conducted among 965 students of medical and non-medical universities in the cities of Lahore, Rawalpindi and Islamabad. Consent was taken for using the Hamilton Anxiety Rating Scale and Insomnia Severity Index for scoring of anxiety and insomnia respectively. An online questionnaire made in Google forms was used for data collection. Independent t-tests, Pearson Correlation and Regression analysis were performed using SPSS v25.

Results: Increased prevalence of anxiety and insomnia in non-medical students as compared to the medical students was observed. There was statistically significant strong correlation between anxiety and insomnia of the enrolled subjects (r=0.742, p<0.001). A linear regression equation was formulated. Increased prevalence of anxiety and insomnia in females was also determined.

Conclusion: Non-medical students, compared to medical students, among which, females, compared to males, were more likely to suffer from anxiety and insomnia during lockdown.
Indonesian Rheumatology Association (IRA) Recommendations for Diagnosis and Management of Axial Spondyloarthritis 2021
Authors: Paramaiswari Ayu , R.M. Suryo Anggoro Kusumo Wibowo  , Yulyani Werdiningsih  , Arief Nurudhin  , Surya Darma  , Lita Diah Rahmawati  , Sumartini Dewi  , Rudy Hidayat  , Sumariyono
Published: August 2021

Objective. Recommendations for spondyloarthritis are made to provide guidelines in diagnosis establishment, therapy, and monitoring of axial spondyloarthritis cases.Method. Literature searches were conducted online. The drafting team determines the levels of evidence (LOE) and grades of recommendation (GOR). After conducting a discussion, each recommendation that has been agreed upon by the drafting team is then classified based on the levels of evidence and grades of recommendation. The final step in the preparation of these recommendations is to determine the level of agreement (LOA) on each recommendation carried out by a team of panelists who have been appointed by IRA.Results. Twenty recommendations regarding axial spondyloarthritis were established. Strong recommendations or GOR A include: Ax-SpA diagnosis can be made according to the 2010 ASAS criteria, or the 1984 modified New York criteria specifically for the US; conventional radiographic examinations and MRI of the sacroiliac joints and vertebrae may be used as evaluators of disease activity and predictors of therapeutic response, as well as patients who do not respond to NSAIDs (within 4 weeks) can be administered a combination of NSAIDs and anti-TNF, and if it is not possible, a combination of NSAIDs and anti-IL-17A (Secukinumab, Ixekizumab).Conclusion. These recommendations provide a direction for clinicians to diagnose and manage spondyloarthritis.
The effect of iron on the expression levels of calcium related gene in cisplatin resistant epithelial ovarian cancer cells
Authors: Kucukkaya Bahire , Erdag Demet , Akbas Fahri , Yalcintepe Leman
Published: August 2021

Aim: Anticancer drugs (chemotherapeutics) used in cancer treatment (chemotherapy) lead to drug resistance. This study was conducted to investigate the possible effect of iron on calcium homeostasis in epithelial ovarian cancer cells (MDAH-2774) and cisplatin-resistant cells of the same cell line (MDAH-2774/DDP).
Methods: To develop MDAH-2774/DDP cells, MDAH-2774 (MDAH) cells were treated with cisplatin in dose increases of 5 μM between 0 μM and 70 μM. The effect of iron on the viability of MDAH and MDAH/DDP cells was determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide test at the end of 24 h incubation.
Results: At increasing iron concentrations in MDAH and MDAH/DDP cells, the mRNA gene of fifteen genes [inositol 1,4,5-triphosphate receptor (IP3R)1/2/3, ryanodine receptor (RYR)1/2, sarco/endoplasmic reticulum Ca2+ ATPase (SERCA)1/2/3, Na+/Ca2+ exchange (NCX)1/2/3, and plasma membrane Ca2+ ATPase (PMCA)1/2/3/4] associated with Ca2+ differences in expression were determined by quantitative reverse transcription-polymerase chain reaction. Changes in IP3R2, RYR1, SERCA2, NCX3, PMCA1, and PMCA3 gene expressions were observed in iron treatment of MDAH/DDP cells, while changes were detected in iron treatment of MDAH cells in IP3R1/2/3, RYR1/2, SERCA1/2/3, NCX2/3, and PMCA1 expressions.
Conclusions: This changes in the expression of calcium channels, pumps, and exchange proteins in the epithelial ovarian cancer cell line and in cisplatin-resistant epithelial ovarian cancer cells suggest that iron may have an important role in regulating calcium homeostasis. Due to differences in the expression of genes that play of an important role in the regulation of calcium homeostasis in the effect of iron, drug resistance can be prevented by introducing a new perspective on the use of inhibitors and activators of these genes and thus cytostatic treatment strategies.
ВСЕУКРАЇНСЬКИЙ ВЕБІНАР З НАЦІОНАЛЬНО-ПАТРІОТИЧНОГО ВИХОВАННЯ «УКРАЇНА — МОЯ БАТЬКІВЩИНА»
Authors: Рейпольська Ольга Дмитрівна , Малиношевський Руслан Васильович
Published: August 2021

Представлено результати роботи Всеукраїнського вебінару з національно-патріотичного виховання «Україна — моя Батьківщина», який організовано з нагоди 30-річчя Незалежності України і проведено 22 червня 2021 р. Мета вебінару полягала в обговоренні актуальних проблем розроблення та впровадження технологій національно-патріотичного виховання дітей дошкільного віку в освітньому процесі закладів дошкільної освіти України, презентування новітніх практик та найкращого досвіду щодо виховання національної ідентичності дітей дошкільного віку в умовах закладів дошкільної освіти. Організаторами вебінару виступили Міністерство освіти і науки України, Національна академія педагогічних наук України (Відділення загальної педагогіки та філософії), Інститут проблем виховання Національної академії педагогічних наук України, Державна установа «Український інститут розвитку освіти».
Characteristics of Spray Angle and Discharge Coefficient of Pressure-Swirl Atomizer
Authors: Zulkifli Abdul Ghaffar  , Salmiah Kasolang  , Ahmad Hussein Abdul Hamid
Published: August 2021

A widely distributed spray is an important feature for an atomizer which is required in various applications such as gas cooling, gas turbine combustion, and fluidized bed granulator. Pressure-swirl atomizer is an example of atomizer which provides a wide spray angle through the swirling effect inside the atomizer. One of the important parameters affecting spray angle is atomizer geometrical constant, K. Another important parameter of pressure-swirl atomizer is discharge coefficient, Cd. Discharge coefficient describes the throughput of the liquid flow. An experimental test-rig was constructed to conduct the performance test of the atomizer. Acquired images were analysed using image-processing software. It was found that K has inverse relation with spray angle and direct relation with Cd. Prediction of spray angle and Cd using existing correlations also yields similar trends with the experimental results, but some parameters still need to be considered to perform an accurate prediction.
RSM for Modelling the CO2 Effect in the Interfacial Tension Between Brine and Waxy Dulang Crude Oil During LSW-WAG EOR
Authors: Musfika Rahman  , Iskandar Dzulkarnain
Published: August 2021

Recent studies on low-salinity waterflooding (LSW) and CO2 water-alternating gas (WAG) use are noteworthy because of their effectiveness in recovered oil content retention in mature fields. s the brine salinity decreases, the solubility of CO2also increases. The CO2in the injected water is expected to reduce the water/oil interfacial tension (IFT), and thus previouslytrapped oil in the rock by capillary forces will flow. However, as of yet, a fewresearches havefocusedon the fluid/fluidinteraction involving waxy crude oil/brinein the LSW-WAGprocess. Twomodels, both of which have been developed from experimental interfacial tension measurements, assist in estimating the CO2's effect on oil/water interfacial tension in the presence and absence of CO2. This objective is accomplished by designing experiments using the modified central composite design (CCD)method in response surface methodology (RSM). Theeffectof pressure, brine salinity, and CO2on oil/water IFT are taken into consideration while modelling.Analysis of variance (ANOVA) was used to determine the optimal values of input variables based on the developed model to obtain an acceptable model. The R-squared values indicate that the developed models arecapable of accurately forecasting the experimental results of oil/water IFT using Dulang crude oil and seven different brine salinities. The findings of this study are expected to shed light on the fluid/fluid interaction behaviour during the LSW-WAG recovery process in a mature field producing waxy crude oil.
Green Route for the Fabrication of ZnO Nanoparticles and Potential Functionalization with Chitosan Using Cross-linkers: A Review
Authors: Hemra Hamrayev  , Kamyar Shameli  , Mostafa Yusefi  , Serdar Korpayev
Published: August 2021

Zinc oxide is of significant importance for many industries due to its versatile properties, which have been enhanced with the production of this material in the nanoscale. Recent interest in the preparation of metal oxide nanoparticles using biological approaches has been reported in the literature. This technique known as “green synthesis” is an environmentally benign process than conventional methods like physical and chemical synthesis methods. Zinc oxide nanoparticles (ZnO-NPs) have been successfully obtained by green synthesis using different biological substrates like chitosan. Chitosan is biocompatible, biodegradable polymer having exclusive physical and chemical properties. Chitosan/metal oxide nanocomposite is a promising nanomaterial with enhanced properties for multiple functionalities. Therefore, this review discusses favorable approach in the formation of cross-linked Chitosan/ZnO nanocomposites attracting significant attention in various fields such biomedical due to their unique biodegradable, biocompatible, non-toxic nature. The use of biological sources, fabrication of green synthesized ZnO nanoparticles and its applications is briefly discussed. Overall, this review is a comprehensive study for the synthesis of ZnO-NPs using biological sources counting on their features and applications.
Synthesis and Properties of Chitosan Nanoparticles CrossLinked with Tripolyphosphate
Authors: Mostafa Yusefi  , Pooneh Kia  , Siti Nur Amalina Mohamad Sukri  , Roshafima Rasit Ali  , Kamyar Shameli
Published: August 2021

Chitosan nanoparticles (ChNPs) have been extensively examined for various biomedical applications due to their advantages include large surface area, biodegradability, and biocompatibility. The purpose of this research was to synthesize ChNPs using a simple ionic gelation technique by the interaction of low molecular weight chitosan (LMWC) and sodium tripolyphosphate (TPP) as a cross-linking agent. ChNPs, TPP, and LMWC were analysed by X-ray diffraction (XRD) and Fourier transforms infrared (FTIR) spectra that indicated the formation of ChNPs, attributing to the rearrangement of the nanoparticles after adding the TPP cross-linker into the LMWC solution. XRD analysis exhibited that ChNPs were amorphous, due to the effect of TPP cross-linker. Dynamic light scattering showed the nano-dimension of ChNPs with a hydrodynamic size of 68.50 nm. Thus, the obtained results indicated that the properties of chitosan were improved through converting it into nanoparticles using TPP initiated ionic gelation procedure.
Green Synthesis of Silver Nanoparticles Using Hibiscus sabdariffa Leaves Extract
Authors: Siti Husnaa Mohd Taib  , Kamyar Shameli  , Roshafima Rasit Ali  , Zahra Izadiyan  , Zatil Izzah Ahmad Tarmizi
Published: August 2021

The present paper reports the synthesis of silver nanoparticles (Ag-NPs) by a green method using Hibiscus sabdariffa (H. sabdariffa) leaves extract as reductant and stabilizer. The synthesized Ag-NPs were characterized by ultraviolet-visible (UV-vis) spectroscopy, transmission electron microscopy (TEM), atomic force microscopy (AFM) and Fourier transform infrared spectroscopy (FTIR). UV-vis spectrum of synthesized Ag-NPs showed a peak at 378 nm. TEM analysis revealed that the particles were spherical and irregular in shape and has average size around 56.52 nm. This structure and size of particles were confirmed by AFM analysis. The UV-vis and FTIR spectrum provides evidence of the presence of caffeic acid component as a representative biomolecule in stabilising the nanoparticles based on previous studies. Hence, this study advocates that H. sabdariffa have potential for synthesizing nanoparticles.
Association between Iodine Intake, Thyroid Function, and Papillary Thyroid Cancer: A Case-Control Study
Authors: Kim Kyungsik , Cho Sun Wook , Park Young Joo , Lee Kyu Eun , Lee Dong-Wook , Park Sue K.
Published: August 2021

Background: This study aimed to assess the effects of iodine intake, thyroid function, and their combined effect on the risk of papillary thyroid cancer (PTC) and papillary thyroid microcarcinoma (PTMC).Methods: A case-control study was conducted including 500 community-based controls who had undergone a health check-up, and 446 overall PTC cases (209 PTC and 237 PTMC) from the Thyroid Cancer Longitudinal Study. Urinary iodine concentration (UIC), was used as an indicator of iodine intake, and serum for thyroid function. The risk of PTC and PTMC was estimated using unconditional logistic regression.Results: Excessive iodine intake (UIC ≥220 μg/gCr) was associated with both PTC (odds ratio [OR], 18.13 95% confidence interval [CI], 8.87 to 37.04) and PTMC (OR, 8.02; 95% CI, 4.64 to 13.87), compared to adequate iodine intake (UIC, 85 to 219 μg/gCr). Free thyroxine (T4) levels ≥1.25 ng/dL were associated with PTC (OR, 1.97; 95% CI, 1.36 to 2.87) and PTMC (OR, 2.98; 95% CI, 2.01 to 4.41), compared to free T4 levels of 0.7 to 1.24 ng/dL. Individuals with excessive iodine intake and high free T4 levels had a greatly increased OR of PTC (OR, 43.48; 95% CI, 12.63 to 149.62), and PTMC (OR, 26.96; 95% CI, 10.26 to 70.89), compared to individuals with adequate iodine intake and low free T4 levels.Conclusion: Excessive iodine intake using creatinine-adjusted UIC and high free T4 levels may have a synergistic effect on PTC and PTMC. Considering both iodine intake and thyroid function is important to assess PTC and PTMC risk.
Antifungal effect of Asphodelus tenuifolius extracts on mycotoxigenic fungi isolated from the imported France soft wheat marketed in the North and southern Ouest of Algeria
Authors: Snoussi Moghtet , Najett Menad , Boumediene Meddah , Abdallah Moussaoui
Published: August 2021

Within the framework of our research of medicinal plants a phytochemical and biological study of Asphodelus tenuifolius has been conducted. The study consisted of evaluating the antifungal activities of most of the chemical constituents extracted from leaves by many solvents and tested on Aspergil-lus flavus, A. parasiticus, A. ochraceus, A. fumigatus, A. niger, Penicillium expansum, Fusarium oxysporum and Alternaria sp.The inhibitory activity of phytochemicals was evaluated on fungi isolating from the imported France soft wheat marketed in Algeria, according to two methods: in agar medium and in Y.E.S. medium. The antifungal activity of the four extracts was evalu-ated against eight mycotoxicogenic fungi, by using agar dilution method. The phytochemical analysis conducted on A. tenuifolius leaves and roots re-vealed the presence of many compounds and the antifungal test results indi-cated a great potential of antifungal activity. Aspergillus species proved the most sensitive but F. oxysporum was the most resistance fungus. These re-sults explain that we can use A. tenuifolius as a natural antifungal agent to inhibit and to control mycotoxicogenic fungi.
Genetic characterization of Spermophagus niger (Coleoptera: Chrysomelidae: Bruchinae: Amblycerini) pest associated to seeds of Sorrel (Hibiscus sabdariffa L.) in Burkina Faso
Authors: KoussoubÃ© Jean Christophe , Mbaye Fatimata , MbackÃ© Dia Cheikh Abdou Khadre , SembÃ¨ne MbackÃ© , Sanon Antoine
Published: August 2021

In Burkina Faso, the seeds of sorrel, Hibiscus sabdariffa L. are attacked by a pest identified morphologically as Spermophagus niger which is maintained all year on seeds and causing considerable damages. In the current study, for the first time, genetic characterization for S. niger was performed to determine its genetic identity and place it in its phyletic group. Mitochondrial gene, the Cytochrome oxidase I (COI) of the pest was partially sequenced after extraction and amplification by Polymerase Chain Reaction (PCR). Then the variability of genetic parameters namely the number of polymorphic and monomorphic sites, the frequencies of the different nucleotides and amino acid composition were determined. The nucleotide sequence of S. niger ob-tained was submitted in Genbank and the accession number is KU710716. Nucleotide sequences of S. niger obtained and those of different species of Spermophagus and Z. subfasciatus available in the GenBank database, we determined the percentage of similarity on the one hand and kinship through Phylogenetics reconstructions on the other hand. The results showed the absence of polymorphic sites for 406 sites obtained with 36.5% of thymine, 17.5% of cytosine, adenine 31% and 15% of guanine. Leucine was the majority amino acid (14.50%); the lysine was minority amino acid (0.76%) and cysteine was absent. The percentage of similarity obtained and phylogenetics reconstructions showed that S. niger is very close to the different species of Spermophagus particularly S. drak and different from Z. sub-fasciatus.
The survival of Pediococcus acidilactici (0110 TAT-1), Lactobacillus casei (NRRL-B 1922) and Listeria monocytogenes (ATCC 1194) on the Curing Types
Authors: Nursyam Happy , B Widjanarko S , Sukoso Sukoso
Published: August 2021

Lactic acid bacteria (LAB) consist of four genera, namely Lactobacillus, Leuco-nostoc, Pediococcus, and Streptococcus. Pediococcus and Lactobacillus are used as starter cultures in the processing of fermented food products such as sour milk, shrimp paste and fermented sausage. . The use of starter culture is intended to speed up the fermentation process as well as inhibiting the growth of other pathogenic bacteria. Common LAB are gram-positive, do not have spores, cocci or bacilli, and produce lactic acid from the fermenta-tion of carbohydrates. Antimicrobial components produced by LAB can inhibit the growth of pathogenic bacteria in fermented products, for example Pediocin produced by P. acidilactici and Lactasin by L. casei. Fermented meat products may possibly be contaminated by Listeria monocytogenes if the implementation is not hygienic. In fermented sausage processing, commonly used preservatives are: NaCl, NaNO2, NaNO3, liquid smoke, pH, and lactic acid. The purpose of this study was to determine the survival of Pediococcus acidilactici, Lactobacillus casei, and Listeria monocytogenes in some kind of curing with different concentrations. The method used is descriptive, where data are shown as mean ± STD. The results showed that P. acidilactici, L. ca-sei, and L.monocytogenes can survive at a rate of NaCl 0-3%; NaNO2 0-100 ppm; NaNO3 0-200 ppm; liquid smoke 0-4%; pH 3 - 5.6; and the incubation temperature of 5-50 °C.
Effect of Curcuma longa on Non-specific immunological profile of Indian Snakehead Channa punctatus infected with Aeromonas hydrophila
Authors: Jain Seema , Varma Manu
Published: August 2021

Curcumin, an Orange Yellow phytochemical, hydrophobic and polyphenolic compound of Turmeric (Curcuma longa.Linn.) has been known to be a potent immunomodulatory agent in many animal species. The aim of our study was to evaluate the immunomodulatory properties and disease resistance against opportunistic pathogen Aeromonas hydrophila in Channa punctatus. Fishes were challenged intraperitoneally with a dose of A. hydrophila(1 ×108 cells/ ml.). Immunocompromised fishes were given three different doses of Curcumin viz. 0.5 mg, 1.0 mg, 1.5 mg / 100gm of body weight respectively. Treated Fishes were sacrificed on 3, 5,7 and 10 day after the dose was given and various Non specific immune parameters were assessed viz. Percentage Phagocytosis, Phagocytic Index, Lysozyme assay, Bactericidal activity and Superoxide anion Production. All the Nonspecific parameters were enhanced significantly. Maximum enhancement was seen on the 5th day with a dose of 1mg/ 100gm body weight and the same dose also showed maximum disease resistance as compared to other two doses.
Fungal colonization of wood and wood products inside the buildings of Sari, northern Iran
Authors: M. Kamali , M. Taheri Sarvtin
Published: August 2021

Fungi are placed in the kingdom Mycota and can colonize wood and wood products. Colonized fungi liberate spores in to the air, and spores can be transported over long distances by air currents. Fungal spores can contain multiple dangerous components such as allergens, antigens and mycotoxins. This study was designed to describe the type and frequency of fungal coloni-zation on wood and wood products inside the buildings of Sari, northern Iran. In this study 17 samples were collected from wood and wood products. The fungal diversity of these samples was investigated by culture-based methods. Descriptive statistics were used to analyze the data. Eight fungal genera and 1739 fungal colonies were recognized. The most dominant fungi were Aureobasidium (45%), Cladosporium (37.38%) and Penicillium (8.91%). In conclusion, the results of our study showed that wood and wood products can be colonized by Toxigenic and allergenic fungi including: Aureobasidium, Cladosporium and Penicillium. These fungi can cause damage to woods and change the appearance of wood product. Therefore, it is necessary to pre-vent the growth of fungi on wood and wood products.
Hypoglycemic and Immunostimulating Activities of Exopolysaccharides from Ganoderma sp. Mushroom in Streptozotocin-Induced Diabetes in Rats
Authors: El-Naggar Randa Ezz El-Din
Published: August 2021

The incidence of diabetes mellitus is increasing dramatically worldwide. Different studies support an association between diabetes and decreased function of the immune system. On the other hand, Ganoderma mushroom, and its bioactive compounds, is widely used and recommended by physicians for its supporting effects on immune system. Therefore, this work aimed to test the hypoglycemic and immunomodulating activities of Ganoderma sp. exopolysaccharides (EPS) in streptozotocin (STZ)-induced diabetes in rats. Animals were divided into control, diabetic and Ganoderma EPS-treated (10, 50 or 100 mg/kg BW) diabetic groups, administered with Ganoderma EPS orally for consecutive 3 weeks. Glucose concentrations were measured using test strips, while the immunomodulating activity was determined by measuring the delayed-type hypersensitivity (DTH) reaction, rosette-forming cells (RFCs) and plaque-forming cells (PFCs) responses as well as the in vitro proliferative response of murine splenocytes. The present results showed that induction of diabetes elicited a marked increase in blood glucose concentrations, a reduction in DTH, RFCs, PFCs immunological responses, as well as a decrease in splenocytes proliferation. However, treatment of diabetic rats with Ganoderma EPS alleviated all the above mentioned effects in a dose dependent manner. The present study concluded that treatment with Ganoderma EPS may have the ability to alleviate diabetes by reducing blood glucose concentrations and by enhancing immunity in STZ-diabetic rats sug-gesting its potential application as an antidiabetic agent in pharmaceutical and medical studies.
Antioxidant and Immunomodulating Activities of Mycelial Extract from the Edible Mushroom Pleurotus ostreatus
Authors: Attia Wael Y. , Bawadekji Abdulhakim , Al Ali Khalil H.
Published: August 2021

In addition to its nutritive value, there are ample studies regarding the me-dicinal properties of the mushroom Pleurotus ostreatus fruit bodies. Howev-er, finding such medicinal activities from submerged mycelium culture will be of considerable interest. The present study aimed to determine the antioxidant and immunomodulating activities of P. ostreatus mycelial extract. The scavenger activity was determined using DPPH, while the im-munomodulating activity was determined by measuring the in vitro prolifer-ative capacity of murine splenocytes as well as the phenotypic and matura-tion of bone marrow dendritic cells (BMDCs). The present results showed increases in the scavenging activity of P. ostreatus mycelial extract compared to ascorbic acid control group, and increases in the proliferative capacity of murine splenocytes compared to vehicle control, except with the higher con-centration. In addition, BMDCs stimulated with P. ostreatus mycelial extract elicited increases in surface expression of CD11c+and CD80, suggesting that P. ostreatus treatment directly induces BMDCs to mature. These results re-vealed considerable antioxidant and immunomodulating effects of P. os-treatus mycelium suggesting its potential application as an immunomodu-lating agent in pharmaceutical, nutritional complement and even medical studies.
Molecular docking and high throughput screening of designed potent inhibitor to PTPN11 involved in Peptic Ulcer
Authors: Sahu Mahadev , Sultan Armiya , Barik Manas Ranjan
Published: August 2021

In the current study we carried out computational drug designing and dock-ing studies on Tyrosine-protein phosphatase non-receptor type 11 (PTPN11). Scaffold selection was based on the functional properties of PTPN11. Leads were identified based on several physiochemical properties and we created our library with those new molecules that were generated based on Lipinski's rule of five. Further, we carried out high throughput screening on 21 molecules from scaffolds selected. Screening of molecules was based on the criterions such as, TOPKAT (toxicity analysis) and ADMET (absorption, distribution, metabolism, elimination) properties. Among the ligands de-signed, only one compound was identified to have premium interaction within the targeted domain. Pharmacophore was generated and analyzed for selected drug candidate. Our results suggest that O-(3-hydroxy-4-methoxyphenyl) S-methyl dithio dicarbonate is a potent drug molecule in terms of physiochemical and docking properties. In conclusion, the identified compound has great potential to inhibit tyrosine-protein phosphatase non-receptor type 11 (PTPN11).
Phyto-Distribution of Alien Invasive Species in the Campus of Pune University by Using GPS Mapping and their Interaction
Authors: Ghayal N. A. , Hase C. P.
Published: August 2021

The invasive plant species hamper crops, human activities and become part of dynamic ecosystems, which grow in varied habitats and harsh ecological conditions and often invade the new ecosystems. The campus of Pune University is highly rich in phytodiversity of native and invasive weeds, which interact with each other. The invasive weeds like Cassia uniflora Mill. non Spreng, Alternanthera tenella Colla., Synedrella nodiflora (L) Gaertn, S. vialis Gray and native weed species like Achyranthes are showing dominance in the campus. The GPS mapping indicated that C. uniflora, S. nodiflora, . tenella, Blainvillea acmella, Euphorbia geniculata, Triumfetta rhomboidea and C. obtusifolia were dominant and occasionally forming pure stands in the campus reducing the phytodiversity of natives by substitution. The results on weed-weed interactions indicated that major associations were between Cassia and Achyranthes, Cassia and Bidens . Synedrella population was forming monothickets. The studies on weed-weed associations and interactions at all the sites indicated that native plants were substituted by the encroachment of invasive weeds due to negative interactions. The negative influence of Cassia and Synedrella was prominent through out the campus. The strong positive and negative associations of native and alien weeds in the university campus predicted changing Phytodiversity and ecosystem dynamics. The aggressive nature and invasiveness of C.uniflora and S.nodiflora was confirmed by their respective abundance such as 25.83 and 24.80 as compared to native weeds like Achyranthes (12.93). The investigation clearly proved the declining phytodiversityof native plant species in the university campus, which has perturbed the ecological balance through the release of allelochemicals / ecochemicals in the habitat.
Postharvest life of different cultivars of Narcissus (daffodil) as influ-enced by various preservative solutions
Authors: Iqbal Shameen , Siddique M. A. , Wani Muneeb Ahmad , Din Ambreena
Published: August 2021

Post harvest life has always being of critical importance in high value flower crops. Our investigation was concerned in evaluating the varietal response of different preservative soloutions on post harvest life of Narcissus (daffodil). The effects of the application of citric acid, aluminium sulphate, silver thiosulphate and calcium chloride at three different levels 0, 100 ppm, 200 ppm along with carbohydrate source sucrose 4% on different floral attributes of Narcissus (daffodil) cultivars California, Pheasants eye and Acetea were stud-ied. The recorded traits included water loss/water uptake ratio, scape length, cup depth, cup diameter, relative water content and membrane stability index. Results of this study showed that within all treatments aluminium sulphate + sucrose 4% showed the best effect. Among the cultivars evaluated California proves best in term of parameters studied (overall post harvest life). The minimum values for these traits were recorded in the untreated control.
An innovative model to quantify corneal transparency in donor corneal buttons
Authors: Rose Jeyanth , Wankhar Syrpailyne , Joshua Aarwin , Korah Sanita , Kuriakose Thomas
Published: August 2021

Assessment of corneal transparency in donor corneal buttons has only been performed qualitatively. The quantification of corneal transparency has implications with respect to clinical suitability of the donor cornea and research involving corneal transparency as an outcome measure. In this study an artificial anterior chamber was modified to create a central transparent passage. This was made possible by replacing the base of the chamber with Perspex and a water  tight seal. An inlet and outlet tube was a ached to the sides of chamber. This was done to maintain a standardized pressure within the chamber when connected to an IV bo le. A corneal button rejected for corneal transplant was placed on the artificial anterior chamber and the chamber was  filled with normal saline. A digital camera and a laser source were placed on either side of the chamber at predetermined intervals. Alignment was achieved so that the laser light passed through the center of the cornea. The image of the laser spot was acquired and subjected to image analysis. To test this proof of concept, a human cornea rejected for human transplant was injected with intrastromal saline to create corneal haze. Pre and Post injection images were analyzed. The average pixel intensity that was calculated was found to be 111 pre-saline injury and 17.2 post-saline injection. Pre and Post-saline measurement showed a marked difference in average pixel intensity. This simple inexpensive setup and ease of analysis are advantages of this method of quantification.