bluuebunny/crossref_metadata_2025 huggingface dataset:
Competencies required for the implementation of an efficient supply chain from the perspectives of students and the labour market
Authors: Munkácsi Adrienn
Published: May 2021

The supply chain, the system granting customer satisfaction, is an important field in our changing world. This field’s profit-oriented companies seek employees with the competencies to achieve their goals. This research’s aim was to raise awareness of those competencies that should be developed. The authors questioned 110 supply chain management (SCM) master’s degree (MSc) students from Corvinus University of Budapest (CUB) and performed a significance test on their answers. They were asked to assess 17 competency groups and state the extent to which – on a scale from 0 to 100 – supply chain managers need them. One of the most interesting results was the assessment of presentation skills, which indicated differences between the competencies that companies expected and those that students believed were required. This study not only lays the groundwork for further research but also emphasizes the relevance of those competencies to be developed and the rethinking of training outcome requirements.
Immediate loading: principles, requirements, and soft-tissue management
Authors: Pereverzyev Vladyslav
Published: May 2021

Immediate loading is defined as the prosthetic loading of dental implants within the first week of loading. From a biomechanical standpoint, immediate loading can result in success and survival rates comparable to conventionally loaded dental implants. Immediate implant positioning and loading preserved the papillae and soft tissue contours around the implant. Additionally, overall treatment time is decreased and the patient’s functional abilities are sooner established. Completing this procedure yields the potential for increased patient satisfaction predictably and efficiently. There are multiple factors to consider in determining whether a patient is an ideal candidate for immediate loading. Placement of an adequate number of implants in well-dispersed positions is necessary in successful immediate loading.
Use of a Lumen-Apposing Metal Stent for Management of Pouch Outlet Stenosis After Vertical Banded Gastroplasty
Authors: Cundra Lindsey B. , Marcuard Maurice , Parekh Parth J.
Published: May 2021

Lumen-apposing metal stents (LAMSs) offer a novel alternative for the treatment of anastomotic strictures or short, benign gastrointestinal strictures. In the bariatric realm, LAMSs provide a potentially safer, efficacious, and nonsurgical approach to surgical revision. Here, we present a case where a LAMS was successfully used to manage pouch outlet stenosis from a previous vertical banded gastroplasty.
Estudio Transversal: Prevalencia del Estrés Académico en Estudiantes de Medicina, Asociado al Rendimiento Académico, Universidad de Cuenca, Cuenca – Ecuador, 2015
Authors: Moscoso Zúñiga Cristina Isabel , Barzallo Sánchez Jorge Luis
Published: May 2021

BACKGROUND: Academic stress is the answer at the demands of the academic institution. Itis believed that the level of stress affects directly in the academic performance in positive ornegative ways. The objective of the study was to determine the prevalence of academic stressand the association on the academic performance of medical students. METHODS: It is a cross-sectional study. The universe was performed of 1 060 students, from the first to the tenth cycle in 2015, the sample was taken of 285 students; randomized and It was applied the SISCO Inventory of Academic (modified). The academic performance was determined by the average of the last year studied. Microsoft Excel V15.0 and SPSS Statistics V 15.0 server were used to analyze the data. The statistical association was obtained with Chi2 tests between the level of academic stress and the average. RESULTS: The 91.58 % of the students reported a certain degree of academic stress; 46.7 % moderate intensity and 36.48 % perceived a high intensity level. The prevalence of academic stress in women (95.45 %) was higher than the man (85 %). It was shown that academic stress is not significantly associated with academic performance. CONCLUSIONS: The prevalence of academic stress in students is high and It is not significantly associated with academic performance, affecting mainly the women. It would be important to conduct a study on how students deal with academic stress.
Estudio Clínico y Epidemiológico de Cáncer de Próstata en el Hospital de Especialidades José Carrasco Arteaga de Cuenca - Ecuador, 2010 - 2015
Authors: Orellana Jara María Paz , Cordero Garate Juana Carolina , Duque Proaño Galo Rubén
Published: May 2021

BACKGROUND: Prostate cancer is the fifth most common neoplasms worldwide and the second in man. In Cuenca, according to the sixth epidemiology of cancer, it is the second cause of death in males. METHODS: Observational descriptive study the sample was for convenience, made up with 315 patients with positive biopsy. The established variables were: Signs and symptoms, histopathological type, total prostate specific antigen (PSA) measure, risk factors, Gleason score, differentiation grade and clinical staging. The media and median were obtained as the crossing of variables using Pearson and Spearman correlation coefficient. The software used was STATA 12 version. RESULTS: The most common symptoms were urinary frequency (56.2 %) and dysuria (36.8 %). 312 patients presented adenocarcinoma as histopathology type. The total PSA had a median of 4.4 ng/ml and a media of 34 ng/ml. The media of age was 69 years old. 141 patients presented hypertension. About the Gleason Grading system most of people were moderately differentiated (43.6 %). 67 % of cases were diagnosed during stages I and II. The Rho correlation coefficient was 0.44 between clinical stage and Gleason score; it was of 0.36 between PSA and clinical stage. CONCLUSIONS: It was found a moderately positive association between clinical stage and Gleason score. There is no minimal measure of total PSA that could assure us there is no risk of prostate cancer. More prospective studies are needed in order to find the relation between prostate cancer and risk factors.
Caso Clínico: Tumor Phyllodes
Authors: Vintimilla Pogo Yolanda Elisabeth , Schuldt Cruz Maolly Lucette , Erráez Jaramillo Pablo José , Patiño Patiño Marcia Cumandá , Naula Calle Jessica Alexandra
Published: May 2021

BACKGROUND: The phyllodes tumor represents less than 1 % of mammary tumors, with an incidence of 2.1 per million worldwide, the age of presentation is between 35 to 55 years. Latina women are at higher risk of phyllodes tumor than other ethnic groups. In Ecuador, the cities with the highest incidence are Quito, Guayaquil and Loja according to the National Registry of Tumors. In Cuenca, one case is presented per year. CASE REPORT: Female patient of 46-year-old woman with a history of resection of fibroadenoma in the right breast 2 years; who 6 months ago, presented a rapidly growing, mobile, defined multi-lobed tumor that occupies 80 % of the right breast, BIRADS II ultrasound; mammography BIRADS 0. Fine needle biopsy presents histopathological result of phyllodes borderline tumor. EVOLUTION: Mastectomy was performed with high-grade malignant phyllodes tumor pathology report with negative limits, the patient does not need adjuvant treatment, and it remains good prognosis. CONCLUSION: Malignant phyllodes tumor is rare, but it should be considered as a differential diagnosis in patients older than 35 years, it is standardized treatment surgical, without having demonstrated that an adjuvant treatment can reduce loco or regional recurrence.
Caso Clínico: Uso de Aloinjerto Óseo Estructural en Tumor de Células Gigantes de Fémur
Authors: Avilés Chamaidan Cristhian Xavier , Barrera Carmona ristian Miguel , Márquez Jervi José Eddy , Moreira del Pozo Luis Alfredo , Armijos Vélez Jorge Luis
Published: May 2021

BACKGROUND: Bone giant cell tumor (GCT) is one of the least frequent, most controversial and least predictable tumors in its behavior. We present a case of GCT in the lower limb, which implied the distal femur. The diagnosis required a previous biopsy before proceeding with its en bloc resection, and treatment based on bone allograft. CASE REPORT: Male patient of 43 years of age, mestizo, with no relevant personal or family history. He went to the oncology orthopedics outpatient clinic for presenting a hard and painful mass with gradual increase in size at the level of the right knee, deformity, functional limitation and crepitus in that region, which is why he attends his assessment. EVOLUTION: The patient underwent a lesion biopsy at the level of the distal femur with a pathological anatomy report of giant cell tumor. Bone resection was performed at the tumor level and treatment was performed by allografting the bone structural allograft. A 2-year follow-up was performed and a score of 14/15 according to the Makin scale was obtained as functional results. Osteointegration of the graft to autogenous bone was also evidenced. Excellently at 15 months. We did not find infection, graft resorption or fatigue of the material. CONCLUSIONS: Limb preservation surgery represented by structural allografts is a favorable technique with adequate functionality and osteoingration, increasing the life expectancy of our patients and future revision possibilities. Avoiding amputations, arthrodesis or tumor prosthesis whose cost benefit with the subsequent years end up being high and deteriorating the quality of life in the patient.
Malformaciones urológicas en niños, en el Servicio de Cirugía Pediátrica del Hospital José Carrasco Arteaga. Enero 2014 – Diciembre 2018
Authors: Ordoñez Peña Juan Sebastián , Orellana Proaño Priscila Estefanía , Córdova Neira Fernando
Published: May 2021

BACKGROUND: Congenital urinary tract abnormalities are diverse, and can affect different structures of this system. The importance of early diagnosis is avoiding kidney damage in the children. The aim of this study was to identify the frequency of urinary tract abnormalities in pediatric patients, in Hospital José Carrasco Arteaga Pediatric Surgery Department, from January 2014 to December 2018. METHODS: Descriptive cross-sectional study. The universe were 230 pediatric patients with confirmed diagnosis of congenital urinary tract abnormalities, from Hospital José Carrasco Arteaga Pediatric Surgery Department, from January 2014 to December 2018. Incomplete medical charts were excluded (n=47 children). 183 children were part of the this study. . La malformación más frecuente fue la hidronefrosis transitoria 70%, seguida de reflujo Vesico-Ureteral (RVU) 16.39% (n=30), estenosis pieloureteral 5.46% (n=10), megauréter 6.55% (n=12) y displasia renal 1.63% (n=3). RESULTS: The frequency of urological abnormalities was 2.73% (n = 183), predominately infants with 56%, and 57% male. 26.78% presented with symptoms related to urinary tract infection. Ultrasound was performed in 95% of the children, urethrocistography in 55% and renal scintigraphy in 31%. Prenatal findings were found in 34.97%. The most frequent abnormality was transient hydronephrosis (70%), followed up by vesico-ureteral reflux (VUR) 16.39% (n = 30), pyeloureteral stenosis 5.46% (n = 10), megaureter 6.55% (n = 12) and renal dysplasia 1.63% (n = 3). CONCLUSION: Urological malformations are common between genetic abnormalities, most of them are asymptomatic; locally due to the low rate of prenatal diagnosis, they are diagnosed in between 24 months of age. Transient hydronephrosis is the most frequent abnormality. Urinary tract infections are commonly the starting line in this groups of patients; when malformations are suspected, ultrasound is always suitable.
Caso Clínico: Fractura expuesta grave del dedo índice. Cirugía de rescate con colgajo adipofascial vascularizado homodigital reverso
Authors: Alvarado Iñiguez Xavier Israel , Torres Jáuregui David Alejandro , Zúñiga Cabrera Fulvio Enrique
Published: May 2021

BACKGROUND: Hand trauma has a high incidence worldwide, it accounts nearly 30% of all trauma and medical visits to emergency rooms, fingertip injuries are the most common among hand trauma. The initial management and the proper choice of treatment are important, the main objective is to achieve adequate tissue coverage, in order to avoid unnecessary amputation, prevent complications and functionality loss. CASE REPORT: A 32-year-old male patient presented with crush trauma on right hand resulting in injuries with tissue loss on the fingertips of the second and third finger and traumatic partial amputation of the distal phalanx of the second finger. EVOLUTION: Surgical technique of homodigital vascularized adipofascial reverse flap was performed in second finger and the fracture was managed conservatively, without complications. A weekly follow up was carried out for 2 months with favorable functional, biological and aesthetic results. The third finger was treated with surgical irrigation and debridement and placement of a sub-occlusive bandage, with favorable outcome. CONCLUSION: Homodigital adipofascial reverse dorsal flap has advantages over other types of conventional flaps; it is a simpler, safe and reliable technique, with good postsurgical outcomes in terms of functionality, aesthetics and recovery, needing only one intervention and offering the appropriate coverage to exposed bone and soft tissue, with minimal repercussions on the donor site.
Caso Clínico: Neurofibromatosis Tipo 1, resolución quirúrgica
Authors: Ávila Narváez Juan Andrés , Salamea Avilés Pablo Andrés , Ávila Narváez Jorge Eduardo , Aguirre Vintimilla Marcos Andrés , Salazar Torres Zoila Katherine
Published: May 2021

BACKGROUND: Neurofibromatosis type 1, first described by von Recklinghausen in 1884, is an autosomal dominant genetically transmitted disease, caused by a spectrum of mutations in the NF-1 gen, with unpredictable evolution, that affects multiple organs and systems, such as the skin and the nervous system, also affecting child development and neurocognitive functions. It often requires complex management decisions from the physician that involve a multidisciplinary approach. CASE REPORTS: 9 year old female patient with a history of type 1 neurofibromatosis. She presented with a mass located in the anterior cervical region, occupying also the left hemithorax, compressing the anterior mediastinum, the trachea from its left side, the heart, and the left lung; the mass produced symptoms: dyspnea, dysphagia and pain, so surgical excision of the mass was scheduled. A left cervical-sternotomy-thoracotomy was performed, a 12 x 7cm mass, located at aortic arch level, closely adhered to the cervical-thoracic spine, was excised. EVOLUTION: During the surgical procedure, the patient had profuse bleeding, coming form the left common carotid colateral artery, so abdominal packing was performed, for later resolution. 24 hours later, bleeding control was achieved after the surgical re-intervention. The pathology lab results established that the mass was in fact a neurofibroma. Subsequent follow-up determined symptoms improvement, without late surgical complications. CONCLUSIONS: Neurofibromatosis is a congenital infrequent, disease, with a complex treatment. Although there is no definitive treatment for type 1 neurofibromatosis, comprehensive management can be achieved to improve the patient’s quality of life. Tumors can be surgically removed, although they often grow back.
Evolutionary trajectories of manufacturing firms in the rural Zlín Region of Czechia
Authors: Šťastná Simona , Pavlík Adam
Published: May 2021

The aim of this article is to identify the most important mechanisms of rural industrial development in the context of a highly industrialized peripheral region in Central Europe. We ask if the development of rural manufacturing firms is primarily based on the activity and skills of local entrepreneurs, or whether it is driven by commercial counter-urbanization or cost-motivated inflow of (foreign direct) investment from other regions. Empirical results are based on the case study of the highly industrialized peripheral Zlín Region in Czechia. We have conducted 26 interviews with the company managers in rural municipalities of the Zlín Region. The growth of rural manufacturing firms is path-dependent, usually based on pre-existing economic activities or skills in the same or technologically related local industries. Neither commercial counter-urbanization nor inflow of foreign direct investment played a major role in the development of manufacturing firms in rural municipalities of the Zlín Region.
Estudio descriptivo y validación de un modelo predictivo de severidad en pacientes con infección por SARS-CoV-2
Authors: Villena-Ortiz Yolanda , Giralt Marina , Castellote-Bellés Laura , Lopez-Martínez Rosa M. , Martinez-Sanchez Luisa , García-Fernández Alba Estela , Ferrer-Costa Roser , Rodríguez-Frias Francisco , Casis Ernesto
Published: May 2021

Objetivos

Durante la pandemia causada por el virus SARS-CoV-2 ha surgido la necesidad de identificar variables predictivas que permitan una rápida identificación de aquellos pacientes que desarrollarán la COVID-19 severa para una rápida intervención. Este estudio ha desarrollado y validado un modelo capaz de realizar un pronóstico de severidad de la COVID-19.

Métodos

A partir de datos analíticos, demográficos y comorbilidades de pacientes visitados en el Servicio de Urgencias con sintomatología compatible de COVID-19, se ha realizado un estudio descriptivo y comparativo de pacientes con PCR-RT positiva y negativa para SARS-CoV-2 y de pacientes con enfermedad COVID-19 moderada y severa. La cohorte COVID-19 positiva ha servido para el desarrollo de un modelo de regresión logística.

Resultados

Se han incluido 410 pacientes COVID positivo (303 con enfermedad moderada y 107 con enfermedad severa) y 81 COVID negativo. Las variables predictivas del modelo son: lactato deshidrogenasa, proteína C reactiva, proteínas totales, urea y plaquetas. La calibración interna mostró un área bajo la curva ROC (AUC) de 0,88 (IC95%: 0,85–0,92), con un porcentaje de clasificaciones correctas del 85,2% a un valor de corte de 0,5. La validación externa (100 pacientes) obtuvo un AUC de 0,79 (IC95%: 0,71–0,89), con un 73% de clasificaciones correctas.

Conclusiones

El modelo predictivo desarrollado permite seleccionar desde el Servicio de Urgencias, con una única extracción de sangre y con magnitudes habituales en un Laboratorio Clínico, aquellos pacientes que con mayor probabilidad desarrollarán COVID-19 severa, proporcionando una importante herramienta para la planificación y la toma de decisiones clínicas.
Multi-Layer Counter-Pressure Injection Molding for Thick-Walled Optical Lens
Authors: Liu Y. , Cao L. , Chi W.-K. , Zhang L.-Y. , Yang W.-M. , Xie P.-C.
Published: May 2021

In precision optical applications, plastics thick-walled optical lenses are increasing. Dimensional stability and optical performance are the critical issues that should be addressed for plastic thick-walled lenses. A novel multi-layer counter-pressure injection molding process is proposed in this study. The experimental prism mold with moveable pistons was developed to investigate the effects of layering methods, counter-pressure and their combination on thick-walled optical lenses. The experimental results reveal that counter-pressure injection molding is effective in improving shrinkage, transmittance and refractive index of the thick-walled optical prism. Counter-pressure of the piston provided lower melt velocity and shorter flow path of melt to improve polymer molecules orientation, and also offered continuous holding pressure during the filling stage to eliminate defects such as shrinkage or short shots. The combination of counter-pressure and multi-layer injection molding technology further improved the dimension stability and optical performance of the thick-walled optical lens. Much thinner layers than the final wall thickness of prism ensures shrinkage reduction during the cooling stages. A thick-walled optical prism was fabricated successfully upon applying a multi-layer counter-pressure injection molding process.
Morphological and Mechanical Properties of Thermoplastic Elastomers Based on Recycled High Density Polyethylene and Recycled Natural Rubber
Authors: Fazli A. , Rodrigue D.
Published: May 2021

In this work, thermoplastic elastomers (TPE) are produced by melt mixing of recycled high-density polyethylene (RHD) with two types of off-the-road (OTR) ground tire rubber (GTR). Non-regenerated (NR) and regenerated (RR) rubbers are used to investigate the effect of GTR concentration and regeneration on the blends properties containing up to 90 wt.% GTR. The blend morphology is studied by scanning electron microscopy (SEM) to show incompatibility and low interfacial adhesion between RHD and GTR (NR and RR) especially above 40 wt.% RR. This behavior is attributed to the GTR regeneration process and agglomeration of RR particles with lower surface area and affinity toward RHD compared with NR. In all the compounds, the mechanical properties in tension of RR blends were lower than for NR blends, which is attributed to the degradation of the GTR backbone chains lowering the molecular weight (MW) during the regeneration process. Also, NR has a more important effect on impact strength improvement due to its higher crosslinked structure making the particles more deformable/elastic to absorb the mechanical energy before crack initiation. The experimental results also show that 80 wt.% GTR is the optimum concentration for the production of low cost and eco-friendly TPE based on recycled materials.
Multilevel Analysis of Strain Rate Effect on Visco-Damage Evolution in Short Random Fiber Reinforced Polymer Composites
Authors: Boudiaf M. D. D. , Hemmouche L. , Louar M. A. , May A. , Mesrati N.
Published: May 2021

In this study, the strain rate sensitivity of a discontinuous short fiber reinforced composite and the strain rate effect on the damage evolution are investigated. The studied material is a polymeric composite with a polyamide 6.6 matrix reinforced with oriented randomly short glass fibers at a 50% weigh ratio (PA6.6GF50). Tensile tests at low and high strain rate are conducted. In addition, interrupted tensile tests are carried out to quantify the damage at specific stress levels and strain rates. To perform the interrupted tensile tests, an intermediate fixture is realized via double notched mechanical fuses with different widths designed to break at suitable stress levels. The damage is estimated by the fraction of debonded fibers and matrix fractures. Based on the experimental observations, it is concluded that the ultimate stress and strain, and the damage threshold are mainly governed by the strain rate. Furthermore, it is established that the considered composite has a non-linear dynamic behavior with a viscous damage nature.
Free space optics communication channel with amplitude/frequency shift keying modulation technique based raised cosine line coding
Authors: Eid Mahmoud M.A. , Sorathiya Vishal , Lavadiya Sunil , Abd El-Aziz Ismail A. , Rashed Ahmed Nabih Zaki
Published: May 2021

The objective of the study is to simulate frequency shift keying (FSK)/amplitude shift keying (ASK) modulation schemes with raised cosine line coding based free space optics channel in clear weather conditions. The max. Q and optical signal/noise ratio (OSNR) with FSO channel length variations are simulated for the previous and proposed models at DRs of 10 Gbps, and also the max. Q factor with data rate (DR) variations is demonstrated for the previous and proposed models at 10 km FSO channel length. Max. Q, min. BER, signal power (SP), noise power, and total optical power (TOP) based FSK and ASK modulation schemes are illustrated through APD receiver with FSO channel length of 10 km.
Phytohemagglutinin ameliorates HFD-induced obesity by increasing energy expenditure
Authors: Zhang Yunxia , Li Jin , Wang Hui-hui , Li Jiao , Yu Yue , Li Bo , Huang Li , Wu Changjing , Liu Xiaomeng
Published: May 2021

Despite all modern advances in medicine, there are few reports of effective and safe drugs to treat obesity. Our objective was to screen anti-obesity natural compounds, and to verify whether they can reduce the body weight gain and investigate their molecular mechanisms. By using drug-screening methods, Phytohemagglutinin (PHA) was found to be the most anti-obesity candidate natural compound. Six-week-old C57BL/6J mice were fed with a high-fat diet (HFD) and intraperitoneally injected with 0.25 mg/kg PHA everyday for 8 weeks. The body weight, glucose homeostasis, oxygen consumption and physical activity were assessed. We also measured the heat intensity, body temperature and the gene expression of key regulators of energy expenditure. Prevention study results showed PHA treatment not only reduced the body weight gain but also maintained glucose homeostasis in HFD-fed mice. Further study indicated energy expenditure and uncoupling protein 1 (UCP-1) expression of brown adipose tissue (BAT) and white adipose tissue (WAT) in HFD-fed mice were significantly improved by PHA. In the therapeutic study, a similar effect was observed. PHA inhibited lipid droplet formation and upregulated mitochondrial-related gene expression during adipogenesis in vitro. UCP-1 KO mice displayed no differences in body weight, glucose homeostasis and core body temperature between PHA and control groups. Our results suggest that PHA prevent and treat obesity by increasing energy expenditure through upregulation of BAT thermogenesis.
The Application of Crisis Intervention in Middle-Aged and Young Patients with Acute Myocardial Infarction after PCI
Authors: Weng Caiyun , Gao Chunmei , Chen Jianjing
Published: May 2021

Objective: To investigate the effect of crisis intervention in middle-aged and young patients with acute myocardial infarction after percutaneous coronary stent implantation (PCI).
Methods: A total of 108 middle-aged and young patients with acute myocardial infarction undergoing PCI were selected from July 2018 to July 2019 in the Department of Cardiology, Hai'an County People's Hospital. They were divided into two groups, according to a random number table, with 54 cases in each group. The control group implemented routine postoperative intervention, and the intervention group implemented postoperative crisis intervention. The changes in the two groups' sense of crisis, mental state, quality of life and hope level before and after the intervention were compared.
Results: The emotional, behavioral, and cognitive scores of the intervention group were lower than those of the control group after 4 weeks of intervention (P < .05). The mental state scores of the intervention group were lower than those of the control group (P < .05). Also, the various quality of life scores were higher than those of the control group (P < .05). The intervention group’s hope level scores were higher than the control group (P < .05) after 4 weeks of intervention.
Conclusion: The application of crisis intervention to middle-aged and young patients with acute myocardial infarction after PCI can reduce the sense of crisis, improve their mental state and quality of life, and raise the level of hope.
Optimization of mixed enzymolysis of acid-exploded poplar wood residues for directional bioconversion
Authors: Liu Na , Chen Jienan , Zhan Peng , Zhang Lin , Zhou Xiaoxun , Zeng Baiquan , Wu Zhiping , Wang Hui
Published: May 2021

Enzymolysis is a key bioconversion process of lignocellulosic biomass. The optimization of enzymolysis is important for its efficiency and accuracy. There is potential to solve the problem of low reducing sugar in the conversion of lignocellulose to bioethanol. In this study, mixed cellulases (cellulase and β-glucosidase) were used in the enzymolysis of acid-exploded poplar wood residues. The mixed enzymolysis process was optimized by response surface area test, and its kinetics model was established based on the Michaelis-Menten equation. The optimal parameters of the mixed enzymolysis were: initial, pH 5.2; temperature, 46 °C; and cellulase to β-glucosidase ratio, 1.62. These parameters resulted in enzymatic saccharification efficiency 1.3 times as high as that of the control (conducted with un-optimized parameters). The modeling revealed that there was a strong correlation (R2 = 0.97) between substrate concentration and reaction rate. Multiple simultaneous saccharification and cofermentation (MSSCF) developed in the laboratory was also employed to verify the optimal parameters. The mixed enzymolysis process carried out with the optimal parameters achieved an ethanol concentration of 30.09 ± 0.49 g/L, which was 1.64 times higher than that conducted with un-optimized parameters. The fermentation time was also reduced by 24 h. Overall, the optimization of mixed enzymolysis process could enhance the efficiency of lignocellulosic directional conversion to bioethanol.
Geological-petrophysical characteristic of Silurian deposits of the Volyn-Podillya edge of the East-European Platform
Authors: KUROVETS Ihor , LYSAK Yulia , CHEPUSENKO Pavlo , MYKHALCHUK Stepan , KUCHER Roman-Danylo
Published: May 2021

Taking into consideration well logging of the Silurian deposits of the Volyn-Podillya plate, the materials of laboratory investigations of petrophysical parameters of reservoir rocks were analyzed and systematized. Studied were capacity-filtration properties of reservoir rocks as well as their lithological-petrographical and structural-textural features. An analysis of the distribution of petrophysical parameters of the Silurian deposits of the Volyn-Podillya plate was executed by the methods of mathematic statistics. Main statistics and correlation coefficients between individual parameters were calculated, histograms of the distribution of the porosity factor Kpor and the permeability factor Kper, volumetric weight δ and carbonation C in rocks were compiled, regression equations between parameters and their alteration with depth were formed. Petrophysical parameters of the samples available for carbonate and terrigenous rocks of Silurian were analyzed separately. Executed investigations of petrophysical properties of rocks testify that in the Silurian deposits the carbonate reservoirs with the complex structure of the porous space were distributed. A visible alteration of capacity-filtration parameters of rocks of Silurian deposits is observed with depth. Porosity of rocks decreases with depth, but permeability increases that is a confirmation of the formation of the secondary fractured-covernous porosity. Increase in the permeability factor with depth is characteristic of carbonate rocks. According to geological-geophysical data available, the reservoir rocks with better capacity-filtration properties are distributed in the zone of the barrier reef. The best reservoir parameters are characteristic of cavernous dolomites and limestones at the Lokachy area and in the region of Lutsk. Reservoir rocks of porous type are practically absent at depths over 2500 m. Here a significant role in improving of collecting properties of rocks belongs to their fracturing. Microfractures are observed in clayed limestones, marls and clay rocks. Under favourable geodynamic conditions the subvertical zones of disconsolidation occur in which composite reservoir rocks with fracture porosity may be formed.
Positive and Negative Creativity: Individual and Environmental Influences on Government and Private Employees
Authors: Suralaga Fadhilah , Dewi Mulia Sari , Tresniasari Nia
Published: May 2021

Research on creativity as an attitude, thinking ability, and creative behavior developed in the education sphere is profoundly related to positive things. Meanwhile, the research for negative creativity or the allegedly dark side of creativity is still very limited both in education and in the industrial world. This study examines the influence of internal factors (personality and intelligence) and external factors (organizational climate and organizational culture) on positive and negative creativity. The sample comprised 180 government employees in a ministry office and 150 private employees at a well-known insurance company in Jakarta. The results of this study show that for government employees, positive creativity mainly influenced by internal factors, namely the openness personality type, and none of the external factors affects. Simultaneously, negative creativity influenced by external factors, particularly the goal-oriented organizational climate, and none of the internal factors affects. On the other hand, private employees have various positive creativity influenced by internal factors (such as extraversion personality and neuroticism) and also external factors (the culture of cooperation and customer orientation). In contrast, negative creativity influenced by external factors of the organization, specifically the internal process that runs within the organization.
Association Between Self-Efficacy and Aggression Among College Students
Authors: Malagonda Patil Vishwanath , Minchekar Vikas S.
Published: May 2021

Aggressive behavior in sports and group performance is critical in today's scenario. Self-efficacy can play a crucial role in aggressive behavior. Hence, to test this assumption study was undertaken to assess the association between self-efficacy and aggression. It was hypothesized that self-efficacy and aggression are positively and significantly related to each other. This study's sample contained 80 students, and they were recruited from Dr. Ghali College, Gadhinglaj. The sampling technique was non probability sampling in which everyone doesn’t have the same chance for being chosen as a sampling. This study administered self-efficacy measure using the scale by G. P. Mathur and Dr. Raj Kumari Bhatnagar and aggression scale by G. P. Mathur and Dr. Raj Kumari Bhatnagar to 40 male and 40 female college students. Obtained data were analyzed by Student t-test and PPMCC test. Results revealed that there is a significant sex difference in self-efficacy and aggression. Moreover, the association between self-efficacy and aggression among college students was also found significant.
A Novel Dynamic and Fuzzy Value Stream Mapping (DFVSM): System Dynamics and Fuzzy Logic Integration
Authors: Baeza Serrato Roberto
Published: May 2021

Value stream mapping (VSM) is a method to identify waste and activities that do not add value. One of its main disadvantages is that the parameters used in the process and material flows are deterministic. The motivation of this research is to improve the reliability of the estimation of the lead time in VSM, transitioning from a static model to a dynamic model that incorporates uncertainty and imprecision in the data, as well as to develop a novel dynamic and fuzzy value stream mapping (DFVSM) based on integrating system dynamics and fuzzy logic. One of the main contributions of this research is to develop a fuzzy system in the same system dynamics interface that incorporates uncertainty and vagueness to the efficiency and effectiveness percentage variable (OEE%) to increase the reliability of the delivery time planning. The stages of DFVSM are explicitly described and applied to real data for a textile company in southern Guanajuato. A sensitivity analysis of the proposed model was integrated which identifies the critical factors for the delivery of the order, and achievable times were proposed for the delivery times of the supplier and the client, thus reducing the expected delivery time by 28%. One of the relevant conclusions of this work is that, to plan the lead time of an order, the uncertainty of the main parameters such as supplier and customer shipping times be considered to satisfy the customer.
Removal of Pb(II) in Aqueous Solutions Using Synthesized Zeolite X from Ecuadorian Clay
Authors: Medina Daniel F , San Martin Delly M , López Carmen Milena , García Luis V , Aguilar Silvio D , Jaramillo Ximena V , Rosado Daniel , Garcia Lopez Adriana Lucia
Published: May 2021

Zeolite X was synthesized from clay using the alkaline fusion method and hydrothermal treatment to remove Pb(II) in aqueous solutions. Clay and zeolite were characterized through X-ray diffraction and fluorescence (XRD, FRX), as well as through specific surface area (SSA). The adsorbents were prepared as cylindrical extrudates using clay and a clay-zeolite combination (60-40%, respectively). The effects of pH, isotherm, and adsorption kinetics on the removal of Pb(II) in solutions of 80 mg Pb(II)/L were studied. It was possible to obtain a zeolite X from clay, with an SSA of 376 m2/g, 30 times greater than that of clay (12 m2/g). In the combined extrudate was present the zeolitic structure, with an SSA 12 times higher compared to the clay extrudate. The adsorption capacity, at 30 °C and V/m ratio of 1 g/L, is almost double compared to the clay extrudate (24 mg Pb(II)/g vs. 13 mg Pb(II)/g). Adsorption follows second order kinetics, and the Langmuir isotherm equation showed a good fit with the experimental equilibrium data for the two extrudates. The Webber-Morris and Bangham-Burt’s models suggest that pore and film diffusion influence the kinetic mechanism.
The Slovenian-Hungarian Border: A Historical Outline
Authors: Hirnök Katalin Munda , Gradišnik Ingrid Slavec
Published: May 2021

The article presents the facts relating to a century of shifting borders along the frontier between today’s Slovenia and Hungary. As borders primarily symbolize the physical strength of the state, they are an essential subject for people living in borderlands anywhere in the world. Following the Great War, the 1919 delineation of borders in what had for centuries been a stable area (Slovenian March) caused upheaval not only for political actors but also for those persons who suddenly found themselves living in separate states. Later in 1948, the border became part of the Iron Curtain, which completely paralyzed communications in the Yugoslavian (Slovenian)-Hungarian cross-border region and branded it with a highly specific historical and social dynamic. The turn of the 1980s to the 1990s was marked by the fall of the Iron Curtain between the East-European (communist) and Western (capitalist) worlds. After 2004 and 2007, when the Slovenian and Hungarian states became first members of the European Union and then the Schengen area, it seemed that the border would fade away.
A fatal rabies case and experiences of a mass post exposure prophylaxis among healthcare workers
Authors: Sener Alper , Akman Canan , Akca Anil , Varisli Behcet
Published: May 2021

We aimed to monitor the adverse effects (AE) and efficacy of post exposure prophylaxis (PEP) in health care workers (HCWs) exposed to a rabies patient. In this study 109 HCWs and eight household contacts were PEP candidates. Contact persons without infection control precautions were in Group I (high risk-82 cases). HCWs indirectly exposed to environmental surfaces were classified in Group II (low risk-35 cases). PEP schedule was rabies vaccine (RBV) + equine rabies immunoglobulin (eRIG) in Group I and only RBV in Group II. Local and systemic AE were observed in all cases. Efficacy of post exposure prophylaxis (PEP) was determined by rabies development in a six month follow-up. 585 doses of RBV have been used in 117 cases and eRIG has been used in 82 cases. 32 Nurses (39%); 22 emergency medicine technicians (26.8%); 12 doctors (14%); six laboratory technicians (0.07%); six radiology technicians (0.07%); four cleaners (0.05%) were in Group I (82 cases), respectively. One doctor, laboratory technician, nurse and radiology technician (0.02%); two emergency medicine technicians (0.04%) and nine cleaners (25.7%) were in Group II (35 cases), respectively. Routes of transmission were blood in five (0.06%); saliva in 14 (17%); sweat in 50 (61%); CSF/serum in five (0.06%); sexual intercourse in one (0.01%); personal equipment in seven (0.09%) in Group I, respectively. Indirect contact was the only route in Group II. The most common local and systemic AE were seen in Group I; pain at injection side (19 cases) and fever (13 cases). Both of them showed statistically significant difference (P<0.05). Allergic rash has been seen at only one case. PEP failed in one case where the possible exposure way was sexual intercourse. PEP is the safest way to prevent rabies. Infection control precautions were still not enough applied. eRIGs are also safe and have rare AE.
INCORPORATING LINGUISTIC LANDSCAPE INTO ENGLISH WORD-FORMATION TASK IN AN ENGLISH MORPHOLOGY COURSE
Authors: Kweldju Siusana
Published: May 2021

This exploratory case study focuses on the development and implementation of a task called the Inventive English Word Formation in Public Spaces for an undergraduate English Morphology course within the English Language Education program of a university in Indonesia. This task was created based on students’ feedback that they disliked the typical memory-based test, which was reported to have a significant strain on them. In that regard, this task was developed to replace the teacher’s lectures and achievement test to increase students’ learning engagement and understanding of the Word Formation theory. Students were asked to morphologically analyze how Indonesian people invented new English words in commercial signs in linguistic landscapes. Sixty students were involved in the task and they were put into groups of four. Each group was assigned to write a paper reporting how they identified and explained the types and subtypes of word-formation of the invented names. The findings suggested that although students found that the task was more meaningful and engaging than the usual learning procedure, the papers they produced showed that they were still not ready for the demand of academic reading and research skills associated with the task. This task, however, promises positive avenues that can be improved and explored in future studies.
La conformidad: Negociar, pactar, rebajar y... ¿Renunciar a derechos para agilizar el proceso?
Authors:   Universitat di Girona, Ordóñez Cádiz Francesc
Published: May 2021

This work aims to analyze the conformity in the Spanish procedural system. But not exclusively. It pretends that the reader gets an idea that even though the conformity (as well as other forms of negotiated justice) is an advantageous and agile solution, also has a more uncertain side since it implies wavering guarantees and fundamental rights. Without disregarding the negotiations that take place (mainly, in the USA) that can be constraining to extremes that are hardy ethical or not at all. Not everything is acceptable for facilitating the process. This study will allow us to verify the problems of the justice system (slowness and congestion), as well as to analyze an instrument of procedural facilitation such as the conformity, to review its functioning, and for understanding what happens in the USA and in Chile, countries that have been chosen because the former is a conformity-based system, and the latter has an important Criminal Procedure Code and aims at distancing from the plea bargaining.
Violência pós-morte contra travestis de Santa Maria, Rio Grande do Sul, Brasil
Authors: Souza Martha Helena Teixeira de , Miskolci Richard , Signorelli Marcos Claudio , Balieiro Fernando de Figueiredo , Pereira Pedro Paulo Gomes
Published: May 2021

Este artigo busca descrever e analisar as violências vivenciadas pelas travestis em suas trajetórias (que, muitas vezes, culminaram em seus homicídios), direcionando o olhar para as violências que continuam mesmo após a morte. A intenção é compreender um tipo de violência que se manifesta na normalização de gênero pós-morte que busca apagar a história e os rastros da existência travesti. Trata-se de estudo baseado em metodologia qualitativa, por meio de pesquisa etnográfica. A etapa etnográfica deste artigo ocorreu entre os meses de setembro de 2019 e fevereiro de 2020, sendo decorrente do assassinato de cinco travestis. Os resultados indicaram a existência de um dispositivo de normalização pós-morte que atua contra o desejo final das travestis, negando-lhes uma morte digna.
Pattern and spatial associations of commercial trees in the Amazon
Authors: Rodrigues Brenda Letícia , Bruzinga Josiane Silva Costa , Ribeiro Renato Bezerra da Silva , Gama João Ricardo Vasconcellos , Machado Evandro Luiz Mendonça , Oliveira Marcio Leles Romarco de
Published: May 2021

ABSTRACT: This study was conducted to establish the pattern and the spatial associations of the Amazon commercial tree groups. In a region extending across 2,000 ha in the Tapajós National Forest (FNT), Pará, a forest census was conducted. The census included commercial trees of perimeter at breast height (PBH), equal to or greater than 158 cm and the Cartesian coordinates of their bearings. Using Ripley’s K function, the spatial pattern was discerned, with 5 m radius being assumed, and maximum distances varying up to 1,500 m. Then, with 99.8% probability for both, 500 Monte Carlo simulations were performed for the univariate K function, and 500 toroidal simulations were done for the bivariate function.The commercial tree groups, which revealed an aggregated spatial pattern in a minimum of approximately 50% of the analysis distance were namely, Astronium lecointei, Bagassa guianensis, Couratari guianensis, Manilkara huberi, Mezilaurus itauba, and Vochysia maxima. In Brazil, the commercial tree groups, based on the commercialization criteria for tropical trees show random and aggregated spatial patterns with associations of spatial independence.
A review of pharmacokinetic drug interactions between antimicrobial and antiseizure medications in children
Authors: Zaccara Gaetano , Lattanzi Simona
Published: May 2021

Comorbidity between epilepsy and infectious diseases in children is frequent. Pharmacokinetic drug‐drug interactions (DDIs) between antiseizure medications (ASMs) and anti‐infectives can occur and influence their efficacy or cause toxicity. All potential DDIs between ASMs and antimicrobial agents used in children were identified through consultation of drug compendia. Clinical studies, case reports and summaries of product characteristics of all identified drugs were also searched. A typical example of a DDI that is often observed in children is that involving valproate (VPA) and carbapenem antibiotics. This DDI has a unique mechanism of action (inhibits the enzyme that catalyses the hydrolysis of VPA‐glucuronide) and leads to a fall of around 60% of VPA level, associated with seizure recurrence. An example of bidirectional DDI involves the antimycotic voriconzole and several ASMs. Voriconazole is metabolized and is a strong inhibitor of cytochrome (CYP)3A4, CYP2C9/10 and CYP2C19. There is clinical evidence of induction of voriconazole metabolism with possible loss of its efficacy by phenytoin (PHT), while voriconazole increases the levels of PHT. Other ASMs that are inducers of these enzymes, such as carbamazepine (CBZ), phenobarbital, stiripentol and to a lesser degree, oxcarbazepine, might be predicted to decrease the level of voriconazole. Voriconazole might also be predicted to increase levels of cannabidiol, CBZ, lacosamide, midazolam, and zonisamide. DDIs between ASMs and some antiviral agents are potentially even more frequent and clinically relevant.