bluuebunny/crossref_metadata_2025 huggingface dataset:
DEVELOPMENT OF LIVEWORKSHEET LKPD BASED ON PROBLEM BASED LEARNING ON LIGHT MATERIALS
Authors:   UIN Sultan Syarif Kasim Riau, Anisa Miftahul Khirana , Permana Niki Dian ,   UIN Sultan Syarif Kasim Riau, Diniya Diniya ,   UIN Sultan Syarif Kasim Riau, Susilawati Susilawati ,   UIN Sultan Syarif Kasim Riau
Published: June 2022

This research aims to develop LKPD using liveworksheets based on problem based learning on light matter. The research method used is development (research and development) with the Sugiyono development model. The results of LKPD validity have been declared very valid based on the results of validation of learning material experts obtained a value of 88% with a very valid category, and the teaching material expert obtained a value of 88% with a very valid category, and the category of all validators is very valid with a value of 83%. In addition, LKPD is stated to be very practical with a value of 88.89% without revision. Based on the response of students obtained a score of 95.25% with an excellent category. Based on the acquisition of these data, it can be concluded that LKPD using a problem-based learning liveworksheet in light matter is declared very valid and very practical to be used as an IPA teaching material in school.
Blockchain based Transparent and Genuine Charity Application
Authors: Naiknavare Mr. Omkar Sunil
Published: June 2022

Abstract: [21]Charity plays an essential role in our society, and often recognized as a type of social debt, leading to the circulation of a significant amount of money worldwide. We have witnessed increased growth of non-commercial organizations and charity funds through recent years, collecting donations for various philanthropic needs. Unfortunately, charity funds frequently gain much traction from the unscrupulous organization, leading to significant damage for industry's reputation, reducing trust level, affecting the power to boost donations. [22]We strongly believe that utilizing blockchain technology will boost trust, increase efficiency, and encourage more donations. The Charity Webapp project, a blockchain-based charity foundation platform that facilitates the trustful network's formation and is accountable for collecting donation funds. The blockchain network would be comprised of publicly known, trustful, and prestigious organizations. All organizations' operations within the platform will become fully transparent and visual , leveraging properties of immutability, provenance, and nonrepudiation.[23]Therefore the platform will alleviate the results of dishonest actions, revealing fraudulent organizations' activities. Keywords: Blockchain; ensuring trust; NGOs; encryption, Bitcoin, Beneficiary, Donars
Performance Evaluation of Seed-Cum-Fertilizer Drill
Authors: Nahak Subala
Published: June 2022

Abstract: The study was conducted in the farm of the institute to assess the performance of tractor operated seed cum fertilizer drill for sowing paddy seeds. It was observed that there was no effect of stubble on the performance of seed-cum fertilizer drill. However, the loose straw spread on the surface offers some hindrance in the working of the drill. The standards test code was adopted. Each test was replicated minimum three times. The forward speed and depth of sowing were taken as independent variables while wheel slippage and field capacity as independent variables. The field capacity, depth of sowing and seed rate were found to be 0.21 ha/h, 5.50 cm and 0.60 q/ha respectively as compared to 0.50 ha/h, 1.5cm and 1.25 q/ha in case of conventional broadcasting method. The mechanized method of sowing resulted in higher depth of sowing compared to broadcasting method. The tractor operated seed cum fertilizer drill was found to be better as compared to traditional broadcasting method. Keywords: Seed cum fertilizer drill, broadcasting method, Paddy sowing
Credit Card Fraud Detection System
Authors: . Aakash , Kuma Akash , Singh Ravi Pratap
Published: June 2022

Abstract: In today’s world everything is online which also increases the chances of fraud. There are approximately 36.4 percent fraud related to commercial cards which include credit card, debit card, etc. In 2022 there are 64 million people who uses credit card to initiate the transaction, therefore they are also prone to the card fraud. So, in this document we talk about the various machine learning algorithms to predict the credit card fraud based on the previous transaction pattern. Keywords: K nearest neighbour, Machine learning, Credit card, decision tree, random forest
Simulation of Automated Smart Home Using Various Sensors in Arduino Uno Board
Authors: Ghosh Sayan , Singha Abhishek , Majumdar Sanchari , Kumari Shweta , Samanta Subhrakanti , Roy Dr. Sangita
Published: June 2022

Abstract: Technology is advancing every passing year and having an automated home is getting necessary. Earlier, smart homes were considered to be extremely luxurious but now, owing to its huge advantages, it is becoming an important part of our lives. The main advantage of any automated system is to reduce human activity, effort, time and errors due to human negligence. With the increase in energy consumption and population growth, there is a great need to save energy by all means. In addition to that, smart homes provide security to the users, which include security from theft, gas leak and prevents accidents. This paper aims at proposing a model which not only automates our home smartly, but also comes at an affordable cost. Keywords: automation, energy, security, ultrasonic sensor, gas leakage.
ML and AI Based Counseling Chatbot Application: Cafe Buddy
Authors: Srivastava Mudit , Tiwari Shilpi , Kushwaha Sachin , Dixit Yash , Neeraj Mr.
Published: June 2022

Abstract: As the covid outbreak sweeps across the world, the world saw their worst fear and rapid rate of increase in some unwanted medical conditions. No one is left behind by its effect, whether mentally, physically, or economically. People see a surge increase in mental health conditions among youth particularly. Since 2020 we have seen a rapid increase in suicide cases not only among ordinary people but also in every class of people. This clears the thought that only the underprivileged suffer. According to a survey conducted in the U.S., it has been seen a rapid increase in depressive disorder. Depression is the leading cause of disability worldwide. Around 75% of people with mental problems in developing nations go untreated, and nearly 1 million people commit suicide each year. Early identity of melancholy can assist to deal with the intellectual ailment and offer help to those who are affected. Detecting despair in advance may be a big step to dealing with the intellectual contamination and providing help to the human beings tormented by this horrible intellectual contamination. This depression can be effects detected inside the primary levels using the pattern searching for queries. Text assessment, owner assessment (behavior patterns like searches-per-day), temporal assessment (time of day even as people search), and seen assessment of snapshots searched could be the parameters of detecting depression. Keywords: AI, Chat-bot, Extensions, Mental-Health, Counseling
Automatic Door Access Control System Based on Facial Recognition Using ESP32-CAM
Authors: Badashah Dr Syed Jahangir , Usha N. , Reddy K Bhavishya , G Likitha
Published: June 2022

Abstract: Contactless Doorway Security System for Remote Monitoring and Control the usage of ESP32-CAM and a Cloud Server”. People need protection in every place viable while they’re into their houses or far from their houses. An anti-robbery device is a tool or approach used to save you or deter unauthorized intrusion or trespassing hobby in its insurance area. The carried-out device changed into evolved in a mixture of hardware and software. It’s a completely unique protection device made with low-value wi-fi digital digicam and sensors which ensured far-flung tracking and manipulate of doorways. The device empowered the consumer to screen the entrance by taking pictures of the usage of a high-performance wi-fi digital digicam i.e. ESP32-CAM connecting different gadgets and sensors in an IoT network. For different duties like manipulating digital door lock remotely, to click on greater pix, in addition, to get notifications a cloud server application „Blynk‟ changed into used over the clever-phone. A fundamental project changed into to expand this dynamic The Project suggested right here in and titled “Design & Implementation of an IoT Networked. Keywords: ESP32-CAM, Camera, IoT, Cloud, Blynk, Security, etc.
PENGARUH PERMODALAN, PENDAPATAN BUNGA DAN LIKUIDITAS TERHADAP PROFITABILITAS PADA BANK BUMN KONVENSIONAL DI INDONESIA
Authors: Widowati Anya Devina , Abdullah Mohammad Faisal , Arifin Zainal
Published: June 2022

The purpose of this thesis research is to determine the effect of capital, interest income, and liquidity on the profitability of conventional state-owned banks in Indonesia. The data source from this study was obtained from the official website of the Financial Services Authority. The population from this study were 4 banks. The sample from this study used the census method. This study used panel data regression analysis. The results show that the partial test results of the Capital Adequacy Ratio variable has a positive and significant effect on Return on Assets, Net Interest Margin has a positive and significant effect on Return on Assets, and Loan to Deposit Ratio has a positive and significant effect on Return on Assets. Simultaneously, there is an effect of the variable Capital Adequacy Ratio, Net Interest Margin and Loan to Deposit Ratio on Return on Assets.
Socio-Economic Life of Migrant Workers' Wives
Authors: Miftah Khoirul , Su’adah Su’adah , Dwi Kumalasari Luluk
Published: June 2022

Karangtawar Village, Laren District, is located in Lamongan district, where many people, especially the head of the family, become migrant workers, so that wives whose husbands leave them as migrant workers take on two roles to take care of family life at home, whether it's educating their children directly or looking for busyness in public spaces. because to fill social activities or help additional family economy. Like what Alfred Schutz said that human actions become a social relationship when humans give a certain meaning or meaning to their actions, and other humans also understand their actions as meaningful. It will not be separated from the behavior or interactions carried out by the wives of migrant workers. Migrant workers' wives will give a certain meaning or meaning to their actions and other people will understand what migrant workers' wives do. This research was conducted to answer a phenomenon that occurred in the Karangtawar Village community related to the socio-economic life of the wives of migrant workers. In the social life of the wives of migrant workers, apart from their domestic activities, they also carry out public activities such as teaching, establishing good relations with other communities and carrying out other social activities.
Memories of the Future: Traditional Russian Economic Practices in New Foreign Policy Conditions. Article one. Industrial Policy
Authors: Khlutkov A. D. , Mezhevich N. M.
Published: June 2022

Economic and managerial practices of the Russian Empire and the USSR are a set of approaches that are updated in the current economic and political conditions. Industrial policy and import substitution are a set of measures that have already been repeatedly applied in Russian and Soviet history. The classic liberal model of the modern Russian economy provides for the limited use of such tools. This is due to the fact that there are no relevant management structures.
Catherine the Great in the History of Russia
Authors: Gridnev V. P.
Published: June 2022

The purpose of the article is to evaluate the management activities of Empress Catherine II during the reign from 1762 to 1796.

Objective: to analyze the organizational activities of Catherine the Great, aimed at reforming the entire system of state and local government of Russia.

Conclusion: experience, an active life position and the results of the state building of Catherine II indicate that women can be not only guardians of the family hearth, but also successful leaders, as evidenced by the numerous positive assessments given to her by well-known and respected Russian historians and foreign statesmen.
The Imperial Power and Russian Society in the First Quarter of the XVIII Century: The Problem of Gaining Trust
Authors: Stetckevich E. S.
Published: June 2022

The article analyzes the process of changes in the sphere of state and local government during the first quarter of the XVIII century. Considering the features of the city government reform, the introduction of new institutions and procedures in the field of management, the author concludes that during this period the boundaries of trust between the tsarist/imperial authorities and persons involved in process of management were changed. As a result of a deliberate rejection of the aristocratic model of public service, a significant number of representatives of the urban and noble classes were involved in the process of management. The author used problem-chronological, historical-typological, historical-critical methods, as well as the method of content analysis. It is concluded that although many innovations of the first quarter of the XVIII century were not of a long-term nature, they served as the basis for subsequent transformations of the second half of the XVIII century.
On a Question of a Scientific and Technical Cooperation between the USSR and Western Countries in the Field of Energy
Authors: Avdanin V. V.
Published: June 2022

The Stalinist industrial modernization of the USSR, which began in the 1930s, was carried out on the basis of imported technological resources. The transition from the use of foreign equipment to the mass production of domestic analogs of equipment took place gradually, overcoming the difficulties of the post-war period. As a result of the modernization of the energy industry of Leningrad at the turn of the 1940s-1950s a base of import-substituting production of all-Union significance was created. The article analyzes the main problems and features of the state energy policy in the period 1940–1980s, assesses the impact of industrial management reform on the development of the energy industry in the late 1950s, the author notes the specific role of leading party bodies in this process.
Risk of COVID-19 and Psychological Impact of the Pandemic in Swiss Primary Care Physicians
Authors: Sebo Paul , Broers Barbara , Moussa Amir , Cohidon Christine , Favrod-Coune Thierry
Published: June 2022

Background and Objectives: There is limited data on primary care physicians (PCPs) who suffered from COVID-19. We aimed to assess the proportion of PCPs with COVID-19, the proportion hospitalized with COVID-19, and the number of days off work. We also explored their psychological suffering due to the pandemic.
Methods: We selected a random sample of 1,000 PCPs practicing in the seven cantons of Western Switzerland (November/December 2020). PCPs were invited by mail to complete a questionnaire.
Results: The participation rate was 51% (N=506). The burden of disease was high among PCPs: 13% suffered from COVID-19, 0.4% needed hospitalization, and 10 days off work were required on average. In addition, many PCPs reported experiencing heightened psychological symptoms, mainly fatigue (53%) and stress/anxiety (48%).
Conclusions: These findings highlight the urgent need to implement preventive measures to reduce the risk of COVID-19 and psychological illness in PCPs.
Toward a New Epistemology for Medical Science
Authors: Henderson David
Published: June 2022

The use of race remains common at all levels of medical science and practice, including education, research, and care delivery. There are ongoing vigorous debates about the validity of the manner in which race is used. Unfortunately, when one looks closely at the manner in which race is used, what one often finds is in fact racism. This article explores some of the ways in which the development of the concept of race as a biological construct, was used to justify racism, and shaped the early development of scientific thought. This historical perspective is used to elaborate the ways in which those seminal ideas continue to distort medical research, education, and care delivery, and perpetuate health disparities.
Cannabis sin tabú: Análisis de la situación del consumo de cannabis en Costa Rica
Authors: Rodríguez-Villalta Paula Camila
Published: June 2022

Al igual que otros países latinoamericanos, Costa Rica ha motivado la discusión en torno a la legalización del cannabis y la producción para uso industrial y medicinal. En un contexto social marcado por una opinión pública polarizada, el debate se ha centrado principalmente en su carácter ilegal y en su alto consumo en la juventud costarricense, esto ha repercutido en las posibilidades de legislar y desafiar el mercado ilícito del cannabis. Las discusiones sobre las dinámicas de un abuso o uso del cannabis, debe ser analizada bajo una mezcla de variables y factores etarios, geográficos, económicos y culturales. Lo anterior, permite que esta investigación profundice en un análisis del fenómeno del consumo del cannabis en la sociedad costarricense. Este proceso se realiza con literatura, investigaciones y datos relacionados al consumo de esta sustancia psicoactiva. Además, el artículo concluye en que se mantiene una percepción negativa en torno a los diferentes usos del cannabis; no así, la recepción y la respuesta a la que se exponen las personas motivan la expresión de opiniones alternativas.
Relaciones agroambientales en sistemas productivos rurales
Authors: Sanclemente Reyes Óscar Eduardo , Ararat Orozco Miltón César , Mejía Ballesteros Julián Eduardo , Álvarez Ríos Leonardo , Montoya Rendón Julio César , Arango Arias Ángela María , Arteaga Aguilera Luis Felipe , García Arboleda Mauricio , Gallo Valdés Pablo Iván
Published: June 2022

Como externalidades se distinguen aquellos aspectos ambientales no deseados en los sistemas de producción agropecuarios que en últimas afectan su sostenibilidad; por ejemplo, la pérdida de la agrobiodiversidad por simplificación del germoplasma, la degradación del suelo por uso excesivo de maquinaria y aplicación de fertilizantes sintéticos, la contaminación del agua y el aire por solubilidad de moléculas empleadas en el manejo de arvenses, plagas y enfermedades, entre otros, que limitan su reproducibilidad en el tiempo, reducen los beneficios económicos obtenidos por los produc-tores y, en últimas, ocasionan su deserción del sector. No se trata solo de analizar cómo las prácticas de agricultura convencional afectan estos sistemas de producción, sino también de evaluar alternativas de manejo que reduzcan estos impactos, basadas en la simulación de procesos que ocurren naturalmente en los ecosistemas. Entre estos procesos se destacan el aprovechamiento de la energía solar para generación de biomasa, sobre todo por ser Colombia un país de trópico, el incremento de la diversidad en sistemas de cultivo aprovechando las relaciones sinérgicas entre las especies, el manejo a favor de los agroecosistemas de los ciclos biogeoquímicos de elementos como el carbono, nitrógeno, fósforo y potasio, el incentivo de los organismos del suelo como transformadores de materia orgánica, la estabilización y habilitación de residuos como abonos y sustratos orgánicos mediante procesos de compostaje y el aprovechamiento de materiales vegetales fibrosos para elaboración de materiales de construcción con el fin de ser incorporados en la infraestructura rural. Por esta razón el presente libro se titula Relaciones agroambientales en sistemas productivos rurales. La redacción del libro se basa en el lenguaje técnico-científico y pretende abarcar un gran número de lectores que incluyen agricultores, estudiantes de las ciencias agropecuarias y ambientales, tomadores de decisiones en el sector agropecuario y la comunidad académica en general, con miras de aportar al desarrollo de masa crítica y servir de referencia para otras investigaciones enfocadas al desarrollo de una agricultura más limpia y la producción sostenible de alimentos.
Challenges in enterprise architecture management: Overview and future research
Authors: Brée Tim , Karger Erik
Published: June 2022

Due to the ongoing digitalization, today’s business world is changing rapidly. To stay competitive, companies need to adapt quickly to a fast changing-environment. This can be difficult, as organizations are complex systems consisting of many technical and infrastructural elements. Enterprise architecture management (EAM) is therefore increasingly important to companies when managing their infrastructure and adapting it to environmental changes. Despite its relevance, many companies struggle with challenges related to EAM tasks. Up to now, research lacks comprehensive reviews about the field of EAM and the related challenges. This article aims to close this research gap by conducting an iterative systematic literature review (SLR) to identify relevant EAM challenges in different EAM tasks. Hereto, based on Schmidt and Buxmann (2011), the tasks of EAM are divided into six dimensions — EA documentation, EA planning, EA communication and support, EA programming, EA implementation, and EA governance — which are investigated separately. This article’s result is a comprehensive overview of research in the field of EAM challenges. Additionally, interdependencies between the dimensions are assumed. Furthermore, an outlook on future research opportunities from an organizational, corporate governance, project, and technical perspective is provided.
Frequentist and Bayesian analysis methods for case series data and application to early outpatient COVID-19 treatment case series of high risk patients
Authors: Gkioulekas Eleftherios , McCullough Peter A , Zelenko Vladimir
Published: June 2022

When confronted with a public health emergency where the pre-existing
standard of care is inadequate, significant innovative treatment
protocols can sometimes be discovered by medical doctors at the front
lines based on repurposed medications. We propose a statistical
framework for analyzing the case series of patients treated with such
new protocols, that enables a comparison with our prior knowledge of
expected outcomes, in the absence of treatment. The goal of the proposed
methodology is not to provide a precise measurement of treatment
efficacy, but to establish the existence of treatment efficacy,  in
order to facilitate the binary decision of whether the treatment
protocol should be adopted  on an emergency basis. The methodology
consists of a frequentist component that compares a treatment group
against the  probability of an adverse outcome in the absence of
treatment, and calculates an efficacy threshold that has to be exceeded
by this  probability, in order to control the corresponding $p$-value,
and reject the null hypothesis. The  efficacy threshold is further
adjusted with a Bayesian technique, in order to also control the false
positive rate. A random selection bias threshold is then calculated from
the efficacy threshold to control for random selection bias. Exceeding
the efficacy threshold establishes the existence of efficacy by the
preponderance of evidence, and exceeding the more demanding random
selection bias threshold establishes the existence of efficacy by the
clear and convincing evidentiary standard. The combined techniques are
applied to case series of high-risk COVID-19 outpatients, that were
treated using the early Zelenko protocol and the more enhanced
McCullough protocol.
Exploring the Applicability of Un-doped and Doped Rutile TiO2 in Lead-Free Perovskite Solar Cells
Authors: DHARMALE NEERJA , Chaudhury Saurabh
Published: June 2022

On pure and metal, non-metal, co-doped rutile TiO2, DFT simula- tions
are performed. For the stability study of doped materials, the defect
formation energies of non-metal (S), metal (Fe), and metal and non-metal
(Fe/S) co-doped materials are determined. A Ti- rich environment is
preferable over an O-rich environment. With values of 2.98 eV, 2.18 eV,
1.58 eV, and 1.40 eV, the bandgap for pristine, S-doped, Fe-doped, and
Fe/S co-doped materials is found to be direct. The effective masses (m*)
and ratios (R) of charge carriers are also examined, and it is
discovered that Fe/S co-doped material has the lowest charge carrier
recombination rate. The maximum static dielectric constant is found in
the Fe/S co-doped material. Doped material’s absorption spectra shifted
into the vis- ible region. Additionally, using SCAPS-1D simulation
software, a complete solar cell device study using these materials as
ETL is performed for the first time. The absorber layer and the ETL
settings have been tweaked to perfection. Current-voltage (IV)
characteristics, quantum efficiency (QE), capacitance-voltage (CV)
characteristics, and capacitance-frequency (Cf) character- istics are
provided for optimize solar cells.When the smallest degree of defect for
each layer is taken into account, the solar cell with Fe/S co-doped ETL
has the highest efficiency of 34.27%.
Defibrillator Associated Gonococcal Endocarditis
Authors: Martinez-Parachini Jose , Amaral Ansel , Yoneda Zachary , Siegrist Kara , Saavedra Pablo J. , Richardson Travis
Published: June 2022

Endocarditis and cardiovascular implantable electronic device (CIED)
infection are rare presentations of disseminated gonococcal infection
(DGI). We report a case of gonococcal endocarditis with a large
vegetation adherent to the tricuspid valve and CIED leads. Surgical
intervention was able to be avoided through the use of transcatheter
vegetation debulking and CIED extraction.
Refractory Pediatric Acute Myeloid Leukemia expressing NUP98-NSD1 Fusion Gene Conquered by Venetoclax and DCAG
Authors: Chen Hongbo , Xu Huan , Yu Hui , xu jiawei , Wu Xiaoyan , Zhou Fen , Tang Shuo , Feng Xingxing , Luo Quan , Zhang Bingyu , Jin Runming
Published: June 2022

Pediatric AML with NUP98-NSD1 fusion defines a high-risk subset with a
low remission and high relapse rates. There are a few studies on
successful treatment of high-risk AML expressing NUP98-NSD1. We report a
refractory pediatric case who received successful treatment with Bcl-2
inhibitor, venetoclax plus DCAG chemotherapy followed by HSCT, after two
failure courses of conventional chemotherapies. Our case suggests that
the combination of venetoclax and DCAG chemotherapy may be an effective
salvage strategy to refractory AML with NUP98-NSD1. More studies and
clinical trials should focus on the synergistic effect of Bcl-2
inhibitors and hypomethylation agents, especially in pediatric AML.
Clinical features and high-risk factors of plastic bronchitis in children with Mycoplasma pneumoniae pneumonia
Authors: Cui Xiaojian , Zhang Tongqiang , Zhao Lihua , Guo Wenwei , Zhao Li , Zheng Jiafeng , Guo Wei , Zhang Jiayi , Si Ping , Shen Yongming , Xu Yongsheng
Published: June 2022

Objectives：To analyze the clinical characteristics and high-risk
factors of plastic bronchitis in children with mycoplasma pneumoniae
pneumonia (MPP). Methods: Retrospective analysis was performed using
clinical data of 517 children admitted to Tianjin Children’s Hospital
from January 1, 2017, to December 31, 2021. The included children were
diagnosed with MPP and received fiberoptic bronchoscopy interventional
therapy. The patients were divided into plastic bronchitis (PB) (78) and
non-plastic bronchitis (non-PB) (439) groups based on their endoscopic
manifestations and pathological findings.
The clinical characteristics, laboratory results, and imaging findings
were then analyzed. Receiver operating characteristic (ROC) curve and
multivariate stepping-logistic regression analysis were used to predict
the high-risk factors for PB in MPP children. Results: The occurrences
of hypoxemia, peak body temperature, fever duration before FOB, pleural
effusion and extrapulmonary manifestations were more frequent in the
PB group than in the non-PB group (p < 0.05). Furthermore,
WBC, Neut%, CRP, PCT, IL-6, AST, ALT, LDH, CK, , SF, D-D and FIB
levels were significantly higher in the PB group than in
the non-PB group ( p < 0.05). Moreover, the ROC curves and
multivariate logistic analysis showed that hypoxemia, peak body
temperature>39.85 ℃, fever duration before FOB
>10. 5 days, Neut%>72.95%,
IL-6>54.41pg/mL and LDH>479.00 U/L were
independent risk factors for PB in children with MPP. Conclusions: PB
commonly occurs in MPP patients with more severe clinical
manifestations, stronger inflammatory response, and extrapulmonary
complications. Hypoxemia, peak body temperature>39.85 ℃,
fever duration before FOB >10. 5 days, Neut
%>72.95%, IL-6>54.41 pg/mL and
LDH>479.00 U/L may be key predictors of PB in children with
MPP.
Effect of prophylactic caffeine in the treatment of apnea in very low birth weight infants: a meta-analysis
Authors: miao yiqun , Liu Wenwen , Zhao Shuliang , Li Yanan , Jiang Huimin , Wang Aihua , Teng Ping , Zhang Yuanyuan
Published: June 2022

Objective: The purpose of this meta-analysis is to investigate
the effect of prophylactic caffeine use in the treatment of apnea and
other clinic outcomes in very low birth weight infants.
Methods: From inception to 20 May 2022, PubMed, Embase, Web of
Science, Scopus, EBSCO, CNKI, and Cochrane databases were systematically
searched. The meta-analysis was carried out using STATA and RevMan
software. Results: Eleven randomized controlled trials
including a total of 4375 very low birth weight infants were evaluated.
The pooled demonstrated that prophylactic caffeine use was linked with a
significantly lower probability of AOP (OR 0.31, 95%CI: 0.19-0.49,
P<0.001), duration of mechanical ventilation, and
oxygen therapy when compared to control group. It also reduced the
incidence of BPD (OR 0.62, 95%CI: 0.54-0.71, P<0.001),
PDA (OR 0.49, 95%CI: 0.30-0.80, P=0.005) and ROP (OR 0.76,
95%CI: 0.65-0.90, P=0.001), without raising the risk of NEC, IVH
and death before hospital discharge ( P＞0.05).
Conclusion: This meta-analysis confirmed the beneficial effects
of prophylactic caffeine for preventing apnea of prematurity as well as
for improving clinical outcomes. However, further research is needed
before recommending widespread use of caffeine as a prophylactic
treatment in the management of all preterm infants.
HYPERTENSIVE CRISIS IN POSTOPERATIVE CASE OF WILMS TUMOUR-AN UNUSUAL CASE
Authors: Khatavkar Sonal , Suryawanshi Dr.Chhaya , Joey Anilin , Ubhe Dr.Smitha
Published: June 2022

Wilms Tumour also known as nephroblastoma,a highly malignant embryonal
neoplasm,involving one or both kidney. It affects children between 3 to
5 years of age and unilateral but 5% cases bilateral. Disease occur in
about 1 out of 2-2.5 lakh children. Hypertension is noted in children
with wilms tumour either at
LiDAR--camera calibration based on back-projection of background point cloud
Authors: Chen Chengkai , Lan Jinhui , Liu Haoting , Chen Shuai , Wang Xiaohan
Published: June 2022

Calibrating the extrinsic parameters between LiDAR and the visible light
camera is a challenging task, because accurate 3D feature points in
sparse LiDAR point clouds are not easy to extract. In this paper, we
propose a calibration method for estimating the extrinsic parameters of
the LiDAR-camera system by considering the background point clouds. In
this method, additional 3D points behind the calibration object are
introduced to refine the 3D edges and feature points. We process each
scanning line of LiDAR and back-projection points in turn to get
accurate edge points and 3D feature poitns by a refining scheme, thus
leading calibration results robust to sensor noise and distance
variations. Our method has good effect for the LiDAR with poor
horizontal angle resolution, which means our method performance on the
LiDAR-camera system is more applicable for computer vision perception.
Laparoscope minimally invasive surgery in gynecologic oncology and controversies: a review
Authors: Yi Ping , Chen Cheng , Li Mengyuan
Published: June 2022

Laparoscope minimally invasive surgery has gradually become one of the
options for the treatment of early gynecologic malignancies for that it
is superior to open surgery in perioperative efficacy and has no
disadvantage in oncological outcomes. Nevertheless, the Laparoscopic
Surgical Pathway for Cervical Cancer study has shown that early-stage
cervical cancer patients owns higher recurrence rates and shorter
overall survival with laparoscopic surgery compared to open surgery. In
this review, we discuss the current status and controversies regarding
the use of minimally invasive surgery in common gynecologic
malignancies.
Preliminary application experiences of a multi-disciplinary teamwork (MDT) pattern using in the robotic-assisted gynaecological surgery
Authors: Yang Wen , Xu Jia , Gu Chenglei , Zhang Nina , Ye Mingxia , Jin Xiangshu , Li Zhen , Fan Wensheng , Li Li'an , Meng Yuanguang
Published: June 2022

Abstract: Objective Patients’ demographics, perioperative data and
reasons of using MDT pattern were all analyzed to report preliminary
application experiences of an MDT pattern using in the robotic-assisted
gynaecological surgery at a single institution. Design Retrospective and
descriptive study. Setting Tertiary referral center with one surgical
team. Population All the 39 patients who have undergone robotic-assisted
MDT gynaecological surgeries from 2018 to 2021 in Chinese PLA General
Hospital. Methods Various types of robotic-assisted MDT gynaecological
surgeries were carried out by the Da Vinci SI Surgical System. Patients’
demographics, perioperative data and reasons of applying MDT surgeries
were described. Main Outcome Measures Patients’ demographics,
perioperative data and reasons of applying MDT surgeries. Results Most
patients undergone robotic-assisted MDT gynaecological surgeries have at
least one abdominal surgery before. The operation cost and hospital
expense were higher than common laparoscopy. Hospital stays ranged from
7 to 42 days. General surgery department and urological surgery
department were the top two familiar departments involved in
robotic-assisted MDT gynaecological surgeries. Only 4 cases appeared
intraoperative complications in these surgeries. However, postoperative
infection needed to be closely monitored. Conclusions It was indicated
that robotic-assisted MDT gynaecological surgeries applied in severe
diseases could provide both safety and precision, and the pattern was
proved to demonstrate the concept of patient-centered and holistic
treatment. Simultaneously, the MDT pattern could cultivate teamwork in
various departments in the hospital, thus it was beneficial to both
patients and hospitals. Keywords Multi-Disciplinary Teamwork;
Robotic-Assisted Surgery; Minimally Invasive Surgery; Gynaecology
Novel Effective Non-invasive Clinical Treatment for Persistent High-Risk Human Papillomavirus Infection
Authors: Chen Fei , Qu Quan-Xin , Li Zhengyu , Wu Dai-Fei , Zhang Chun-Fa , Lang Jing-He
Published: June 2022

High-risk human papillomavirus (hrHPV) is the major cause of cervical
cancer. The majority of hrHPV infections resolve spontaneously. However,
when hrHPV escapes host’s immune system and establishes persistent
infection in basal keratinocytes, self-clearance of the infection
becomes exactly difficult, and medical intervention is urgently needed
to eradicate viral infection and prevent cervical cancer. This review
aimed to summarize our findings and achievements on REBACIN®—an
anti-viral biologic with low cost, no cold chain and no hospitalization,
and demonstrated that REBACIN® exhibits potent efficacy in clearing
persistent hrHPV infections, promotes regression of associated lesions
via targeted inhibition of viral E6/E7 oncogenes.
Greater abdominal muscle thicknesses and a smaller inter-recti distance at late pregnancy are related to better cord blood gas values. A cross-sectional study from the GESTAFIT project.
Authors: Baena-Garcia Laura , Ocón-Hernández Olga , Alemany Marta De La Flor , Coll-Risco Irene , Manzano Pedro Acosta , Aparicio Virginia A
Published: June 2022

Objectives: The aim of this study was to explore the associations of
abdominal muscles thickness and inter-recti distance (IRD) at late
pregnancy with birth-related outcomes and umbilical cord blood (CB) gas
values. Design: cross-sectional study. Setting: Sport and Health
University Research Institute Sample: One hundred and fifty-two pregnant
women. Main outcome measures: The thickness of the abdominal muscles
(transverse abdominis [TrA], internal [IO] and external obliques
[EO]) and the IRD were measured by ultrasound at the 34th
gestational week. Birth outcomes were collected from obstetric medical
records. Umbilical CB gas concentrations were assessed after birth using
a blood analyzer. Results: Greater TrA and IO thickness were associated
with a higher venous CB PO2 value, both at muscular rest (respectively,
p<0.01 and p<0.05) and during activation (both
p<0.05). A greater activated TrA thickness was associated with
a higher venous CB oxygen saturation (p<0.05). EO thickness at
rest was positively related to arterial CB pH (p<0.05), and
during activation to the 1-minute Apgar test (p<0.05). A
greater IRD was associated with higher arterial (at rest
p<0.01; during crunches p<0.05) and venous CB (at
rest, p<0.05) PCO2 values, and with lower arterial CB PO2
(p<0.05), arterial CB oxygen saturation (at rest,
p<0.05; during crunches p<0.01), and venous CB
oxygen saturation (during crunches, p<0.05, and lower venous
pH (p<0.05). Conclusion: Greater abdominal muscle thicknesses
and a smaller IRD at late pregnancy are related to better umbilical CB
gas values at birth. ClinicalTrials.gov Identifier: NCT02582567
Comparative effect of magnesium sulfate and indomethacin to magnesium sulfate only for Tocolysis in preterm labor in pregnant women in Kosar Hospital, 2019-2021
Authors: hoorshad shiva , pakniat hamideh , ivraghi mehraveh sadeghi , dadashaliha masoumeh
Published: June 2022

Background:Preterm labor is one of the most common pregnancy
complications, and it can have catastrophic effects, including preterm
birth and accompanying complications. This study’s objective is to
compare the efficacy of Magnesium Sulfate and Indomethacin vs Magnesium
Sulfate alone in avoiding preterm labor in pregnant women at Kosar
Hospital in2019–2021. Methods:In this interventional study, which was
conducted as a double-blind, randomized clinical trial on 200 pregnant
women with gestational ages ranging from24to32weeks who were referred to
Qazvin’s Kosar Hospital. Patients were divided into two equal groups and
given magnesium sulfate and indomethacin (group A)or magnesium sulfate
alone(group B).The data then was analyzed with SPSS statistical software
and statistical tests. Results:According to the study’s findings, the
average time interval between receiving the drug and childbirth in group
A was774.71+505.91hours and in group B it was545.77+503.32hours,which
was statistically significant (P0.05). Besides that, the mean
gestational age at the time of pregnancy termination was35.30+250weeks
in group A and35.03+2.65weeks in group B, which was not statistically
significant (P>0.05).The type of intervention, on the other
hand, had a significant relationship with the number of labors during
the first 7 days after starting the drug (P >0.05).
Conclusion:The results showed that magnesium sulfate and indomethacin
were more effective than magnesium sulfate alone in inhibiting and
delaying preterm labor.There were similarities in comparing the findings
of our study with other studies. Keywords:Preterm labor,Magnesium
Sulfate,Indomethacin Financial disclosures:None
Fatal canine parvovirus type 2a and 2c infections in wild Chinese pangolins ( Manis pentadactyla ) in southern China
Authors: 华 彦 , Lina Zhang , Kai Wang , Fuyu An , Dongliang Zhang , Zhang Hailing , Xuelin Xu , Ce Guo , Hongmei Yan , Yingjie Kuang , Zhidong Zhang , Rongguang Lu
Published: June 2022

The Chinese pangolin ( Manis pentadactyla) is a critically
endangered scale-covered mammal belonging to the order Pholidota. Wild
pangolins are notably susceptible to pathogen infection and are
typically characterized by impoverished health. However, little is
currently known regarding the viruses prevalent among pangolins. In this
study, we report the detection of two subtypes of canine parvovirus type
2 (CPV-2), namely, CPV-2a and CPV-2c, both of which caused severe
diarrheal disease in two post-rescue pangolins with fatal consequences.
As in CPV-2-infected dogs, intensive lesion of the mucosal layer of the
small intestines is a prominent feature in infected pangolins.
Phylogenetic analysis revealed that the VP2 viral protein sequences
isolated from one pangolin were classified into the CPV-2c subclade,
with 99.8% identities to a CPV-2c strain (MN832850) isolated from a
Taiwanese pangolin found in Taiwan Province. In contrast, VP2 sequences
obtained from the second pangolin were classified into the CPV-2a
subclade, with 99.8% identities to a CPV-2a strain (KY386858) isolated
from southern China. In this study, we thus confirmed the infection of
pangolins with CPV-2c in mainland China and demonstrate that CPV-2a can
also infect pangolins. Based on these findings, we recommend that
further investigations should be conducted to establish the interspecies
transmission of these viruses among wild pangolins, wild carnivores, and
stray dogs.
Longitudinal Changes in Arterial Stiffness and Heart Rate Variability In Youth-Onset Type 1 vs Type 2 Diabetes: The SEARCH for Diabetes in Youth Study
Authors: Shah Amy S , Isom Scott , D’Agostino Ralph , Dolan Lawrence M , Dabelea Dana , Imperatore Giuseppina , Mottl Amy , Lustigova Eva , Pihoker Catherine , Marcovina Santica , Urbina Elaine M
Published: June 2022

Objectives. We compared
arterial stiffness and heart rate variability (HRV) over time by diabetes type
and determined the risk factors associated with worsening arterial stiffness
and HRV in young adults with youth-onset diabetes.

Research Design and Methods: Arterial stiffness (pulse wave velocity,
augmentation index) and six indices of heart rate variability were measured twice,
4.5 years apart among participants with either youth-onset type 1 or type 2
diabetes in the SEARCH for Diabetes in Youth Study. Multivariable linear
regression models assessed risk factors associated with arterial stiffness and HRV
at follow-up assessment.

Results. Of 1159
participants studied, 949 had type 1 (mean age 17.1 ± 4.7 years, 60.3%
non-Hispanic White, 55% female) and 210 had type 2 diabetes (mean age 22.1 ± 3.5
years, 23.8% non-Hispanic White, 71% female) at initial assessment when diabetes
duration was 7.9 years (both groups). Participants with type 2 vs type 1
diabetes had greater vascular stiffness and more abnormalities in HRV at initial
and follow-up assessment and a greater change over time (all p<0.05). Risk factors
associated with worse arterial stiffness and HRV at follow-up in both types of
diabetes included higher blood pressure, hemoglobin A1c, waist circumference,
and triglycerides, and longer diabetes duration.

Conclusions. Arterial
stiffness and HRV worsened over time with greater changes among those with type
2 compared with type 1 diabetes, and among those with features of the metabolic
syndrome. The risk factor profile documents potentially modifiable pathways to
prevent or limit cardiovascular complications in young adults with youth-onset
diabetes.
Cultural Review of Student Compliance in The Western Region of Indonesia to Health Protocols
Authors: Saragih Sepriandison
Published: June 2022

Health protocols help prevent the transmission of Corona Virus (COVID-19), but the culture of people's adherence to the Covid-19 health protocol in each region is uneven, which is due to the influence of local culture in various blood areas in Indonesia. This study is intended to describe the impact of a culture of adherence to health protocols during a pandemic on students in the Western Indonesia Region. The research approach is quantitative with the type of correlation research, through purposive random sampling, namely 268 students of the Faculty of Teacher Training and Education HKBP Nommensen Pematangsiantar University class of 2018 and 266 students of Faculty of Teacher Training and Education (FKIP) University UHKBPNP class 2019, a total of 534 samples. The data collection instrument used a questionnaire, the data analysis technique used the Kendall's Taub test. The results obtained a significance value of 0.018 <0.05, that there is a relationship between the cultural variables of adherence to health protocols. The correlation coefficient value is 0.554, that the level of relationship between the cultural variables of adherence to health protocols during the pandemic is strong. The direction of the relationship between variables has a positive value of 0.554. Shows the level of obedience culture experienced by students of the Faculty of Teacher Training and Education class 2018 at HKBP Nommensen Pematangsiantar University and students of the Faculty of Teacher Training and Education batch 2019 at HKBP Nommensen Pematangsiantar University based on health protocols.
Recognition the Role of Traditional Villages in Tourism Development from The Legal Pluralism Perspective
Authors: Adnyani Ni Ketut Sari , Wija Atmaja Gede Marhaendra , Sudantra I Ketut
Published: June 2022

Pengelolaan keanekaragaman tradisi dan budaya di setiap daerah di Nusantara lahir dari kemajemukan masyarakat dengan ciri khas berbagai sistem hukum adat yang berbeda dengan hukum nasional yang justru dapat memperkaya khasanah hukum nasional Indonesia. Urgensi kajian artikel ini adalah perlu adanya integrasi kebijakan pembentukan regulasi dan pengelolaan di bidang kearifan lokal seperti adat dan tradisi yang terdapat di setiap daerah di Indonesia. Masalah yang dikaji adalah: pertama, mengkaji kebijakan pengembangan adat dan tradisi dalam konteks pluralisme hukum dan kedua, menganalisis konsep hukum sebagai integrator dalam kebijakan adat dan tradisi dalam konteks pluralisme hukum Indonesia. Hasil penelitian menunjukkan bahwa pertama, perkembangan adat dan tradisi dalam konteks pluralisme hukum selama ini, hukum negara berada pada posisi ordinat dan kearifan lokal berada pada posisi subordinat, sedangkan telah terjadi marginalisasi kelompok masyarakat hukum adat di Indonesia. kebijakan pengembangan adat dan tradisi; dan kedua, konsep hukum dapat berfungsi sebagai integrator antara kepentingan subsistem dalam kebijakan pengembangan adat dan tradisi dalam konteks pluralisme hukum di Indonesia.
SWOT Analysis as The Basis of The Marketing Mix in Increasing Income in PT. Elteha International Singaraja
Authors: Kusuma Gusti Putu Eka , Nurkariani Ni Luh
Published: June 2022

Penelitian ini bertujuan untuk mengetahui analisis SWOT pada PT. Elteha International cabang Singaraja dan mengetahui analisis SWOT sebagai dasar bauran pemasaran. Teknik analisis yang digunakan dalam penelitian ini adalah Reduksi Data, Tampilan Data/Penyajian Data dan Penarikan Kesimpulan dan Verifikasi. Hasil penelitian menunjukkan bahwa PT. Elteha International Singaraja adalah sebuah usaha yang bergerak di bidang ekspedisi. Penentuan strategi pemasaran menggunakan metode analisis SWOT. Data internal dan eksternal diperoleh dari hasil wawancara tidak terstruktur dengan narasumber yaitu pimpinan perwakilan PT. Elteha International Singaraja, karyawan di PT Kerta Gaya Pusaka, hubungannya dengan PT. Elteha International Singaraja dan konsumen tetap di PT. Elteha International Singaraja menyimpulkan sebagai berikut, Faktor internal dan eksternal yang menjadi kekuatan dalam meningkatkan pendapatan pada PT. Cabang Elteha International Singaraja adalah kecepatan dalam pengiriman dibandingkan dengan jasa lainnya, perusahaan juga memiliki kantor yang tersebar di seluruh Indonesia, selalu memberikan keamanan terhadap barang yang akan dikirim, faktor yang menjadi kelemahan dalam meningkatkan pendapatan di PT. Elteha International cabang Singaraja.