bluuebunny/crossref_metadata_2025 huggingface dataset:
A Bi-Objective Fuzzy Credibilistic Chance-Constrained Programming Approach for the Hazardous Materials Road-Rail Multimodal Routing Problem under Uncertainty and Sustainability
Authors: Sun Yan , Li Xinya , Liang Xia , Zhang Cevin
Published: May 2019

Hazardous materials transportation involves extensive risk and cannot be avoided in practice. An advanced routing, however, can help to reduce the risk by planning the best transportation routes for hazardous materials that can make effective tradeoffs between the risk objective and the economic objective. In this study, we explore the hazardous materials routing problem in the road-rail multimodal transportation network with a hub-and-spoke structure, in which the risk is measured by the multiplication of population exposure and the associated volume of hazardous materials, and minimizing the total risk of all the transportation orders of hazardous materials is set as the risk objective. It is difficult to estimate the population exposure exactly during the routing decision-making process, which results in its uncertainty. In this study, we formulate the uncertain population exposure from a fuzzy programming perspective by using triangular fuzzy numbers. Moreover, the carbon dioxide emission constraint is formulated to realize the sustainable transportation of hazardous materials. To optimize the problem under the above framework, we first establish a bi-objective fuzzy mixed integer nonlinear programming model, and then develop a three-stage exact solution strategy that the combines fuzzy credibilistic chance constraint, linearization technique, and the normalized weighting method. Finally, a computational experiment is carried out to verify the feasibility of the proposed method in dealing with the problem. The experimental results indicate that tradeoffs between the two conflicting objectives can be effectively made by using the Pareto frontier to the hazardous materials routing problem. Furthermore, the credibility level and carbon dioxide emission cap significantly influence the hazardous materials routing optimization. Their effects on the optimization result are quantified by using sensitivity analysis, which can draw some useful insights to help decision makers to better organize the hazardous materials road-rail multimodal transportation under uncertainty and sustainability.
The Effects of a Revenue-Neutral Child Subsidy Tax Mechanism on Growth and GHG Emissions
Authors: Kumar Ronald R. , Stauvermann Peter J.
Published: May 2019

Growing population, greenhouse gas emissions, and the pressure to improve economic growth are conflicting and controversial issues at the core of political economy. In this paper, using a theoretical model, we show that by shifting relative costs of child-rearing and costs for education, we can achieve a slowdown in population growth and greenhouse emissions, and an enhancement of economic growth. These goals are based on two fundamental considerations—the quantity–quality tradeoff with respect to the choice of the number, and the educational level of children. An analysis is presented using a standard overlapping generation (OLG) framework that is extended with human capital, endogenous fertility, and changing life expectancy. The environmental impact of economic activities is modeled using a modified IPAT framework. Our results show that it is possible to reduce the level of carbon emissions of the whole economy and to generate a Pareto improvement. Subsequently, an economic strategy is presented that is costless, has various advantages, and particularly useful for countries experiencing high fertility rate that are not sustainable.
Warming and Dimming: Interactive Impacts on Potential Summer Maize Yield in North China Plain
Authors: Hu Qi , Ma Xueqing , He Huayun , Pan Feifei , He Qijin , Huang Binxiang , Pan Xuebiao
Published: May 2019

Global warming and dimming/brightening have significant implications for crop systems and exhibit regional variations. It is important to clarify the changes in regional thermal and solar radiation resources and estimate the impacts on potential crop production spatially and temporally. Based on daily observation data during 1961–2015 in the North China Plain (NCP), the impacts of climate change associated with climate warming and global dimming/brightening on potential light–temperature productivity (PTP) of summer maize were assessed in this study. Results show that the NCP experienced a continuous warming and dimming trend in maize growing season during the past 55 years, and both ATT10 and solar radiation had an abrupt change in the mid-1990s. The period of 2000–2015 was warmer and dimmer than any other previous decade. Assuming the maize growing season remains unchanged, climate warming would increase PTP of summer maize by 4.6% over the period of 1961–2015, which mainly occurred in the start grain filling–maturity stage. On the other hand, as negative contribution value of solar radiation to the PTP was found in each stage, dimming would offset the increase of PTP due to warming climate, and lead to a 15.6% reduction in PTP in the past 55 years. This study reveals that the changes in thermal and solar radiation have reduced the PTP of summer maize in the NCP. However, the actual maize yield could benefit more from climate warming because solar radiation is not a limiting factor for the current low production level.
Characterizing the Embodied Carbon Emissions Flows and Ecological Relationships among Four Chinese Megacities and Other Provinces
Authors: Wang Xuecheng , Tang Xu , Feng Zhenhua , Zhang Yi
Published: May 2019

China has been undergoing a rapid process of urbanization. The urbanization rate, increased from 35% in 2000 to 59.58% in 2018, and is expected to increase to 70% by 2030. As Chinese cities consumed approximately 77% of China’s total energy and emitted about 81% of all carbon emissions in 2017, it has become increasingly necessary to quantitatively analyze city-level carbon emissions and related issues. The present study adopted single regional and multi-regional input-output (MRIO) models to analyze the features of four Chinese municipalities (Beijing, Tianjin, Shanghai and Chongqing) and calculate their embodied carbon emissions (ECE). In addition, we used ecological relationship concepts to analyze the relationships between those municipalities and other regions based on ECE flows through an ecological network analysis (ENA) model. The results show that all four megacities were net importers of ECE, and their imported ECE typically flowed from nearby geographic regions. In addition, exploitation was the main ecological relationship between these four megacities and China’s other regions. Knowing the detailed data related to ECE, ECE flows and the ecological relationships among these megacities could help policymakers establish more comprehensive environment-related policies, which are crucial for achieving sustainable development targets.
Integrating Biophysical and Sociocultural Methods for Identifying the Relationships between Ecosystem Services and Land Use Change: Insights from an Oasis Area
Authors: Wei Hejie , Fan Weiguo , Lu Nachuan , Xu Zihan , Liu Huiming , Chen Weiqiang , Ulgiati Sergio , Wang Xuechao , Dong Xiaobin
Published: May 2019

Identifying the relationships between ecosystem services (ESs) and land use change is crucial for ES management and sustainable regional development. The Manas region in China has witnessed dramatic reclamation activities in its desert areas that resulted in ecological problems. The changes in eight ESs, including crop production (CP), livestock production (LP), soil conservation (SC), water yield (WY), sand fixation (SF), carbon sequestration (CS), habitat quality (HQ), and nature landscape recreation (NLR), were investigated by using biophysical and questionnaire methods. At the regional scale, provisioning services (i.e., CP and LP) showed some performance improvements, whereas most of the regulating services (i.e., WY, CS, and HQ) along with NLR showed a performance decline. Five ES bundles—Upper Mountain, Foothill, Oasis, Oasis–Desert Transition, and Desert bundle—were identified at the township scale via k-means clustering. From 2000 to 2015, the Oasis bundle sprawled as a result of oasisization, whereas the Oasis–Desert Transition and Foothill bundles decreased. We performed a questionnaire survey and a statistical analysis to identify the causes behind the performance improvement/decline of these ESs and found that the land use changes in the Manas region had a significant impact on these services. More than 50% of the survey respondents identified land use changes as the primary driver of the changes in some ESs (i.e., CP, CS, HQ, and NLR). In the correlation and partial correlation analyses, oasisization was significantly and positively correlated with CP but was negatively correlated with WY, CS, HQ, and NLR. We enhanced the reliability of our conclusions by integrating biophysical and sociocultural methods into our investigation of ES and land use change. In view of the huge losses in regulating and cultural services, the Manas region should limit its desert reclamation activities to control the expansion of its oasis and to improve the quality of its cropland. Our results can help formulate effective ES management and land use decisions in the Manas region or similar areas.
Environmental Assessment of a Bio-Refinery Concept Comprising Biogas Production, Lactic Acid Extraction and Plant Nutrient Recovery
Authors: Awiszus Sebastian , Meissner Klaus , Reyer Sebastian , Müller Joachim
Published: May 2019

The process of nutrient recovery from biogas digestate and the extraction of lactic acid from silages is technically feasible, but so far no investigations are available on the environmental sustainability of these technologies in the context of the biogas production chain. The aim of the present study is to show whether the recovery of nutrients from digestate (NR) and the extraction of lactic acid from silages (LA) can be integrated in the biogas production process system in an environmentally sustainable way. The modelling in the present study is based on the standards DIN ISO 14040 and DIN ISO 14044 and the results are evaluated with respect to the 100-year global warming potential, the primary energy demand and the eutrophication potential. Results show that the recovery of nutrients from digestate can be a sustainable solution to the problem of surplus nutrients in biogas regions. Furthermore, lactic acid, which is extracted from silages can provide an environmentally sustainable source of income for biogas plant operators. The urgency of the nutrient surplus problem in these regions calls for increased research and the support of policy makers to foster development activities.
Virtually the Reality: Negotiating the Distance between Standards and Local Realities When Certifying Sustainable Aquaculture
Authors: Amundsen Vilde S. , Osmundsen Tonje C.
Published: May 2019

To account for the many challenges of increasingly global industries, remote regulation measures such as sustainability standards have become continuously more important as a means to ensure global accountability and transparency. As standard certification is assessed through audits, the legitimacy of these standards rests on uncritically evoked norms of auditing, such as independence and objectivity. In this paper, we seek to investigate the claim of these norms as a prerequisite for the audit process of sustainability standards. Based on interviews and fieldwork in the salmon aquaculture industry, we explore how it is possible to concurrently uphold the standard and account for the different conditions of the many local realities. Our findings point to the interactional character of audits, often downplayed for legitimacy purposes, and how this is vital to achieve both ‘distance for neutrality’ and ‘proximity for knowledge production’. We argue for increased transparency concerning the human element of sustainability auditing, thus acknowledging the significance of reciprocal knowledge production when using standards as a route towards sustainability.
Water Treatment Emergency: Cost Evaluation Tools
Authors: Acampa Giovanna , Giustra Maria Gabriella , Parisi Claudia Mariaserena
Published: May 2019

The European Union is committed to enforce limitations to water pollution through specific directives (UWWTD 91/271/EEC). The delay of some EU member states in transposing these directives has had an impact on the quality of the wastewater treatment system. Therefore, it is necessary to intervene with adjustment procedures and construction of new plants. The aim of the study is to carry out an economic feasibility assessment for the construction costs of an urban wastewater treatment plant of medium-low capacity (<50,000 Population Equivalent or pe) according to a simplified process diagram, and help in the planning of new investments. We propose a methodology based on cost functions according to two different procedures: synthetic estimate of the costs for civil works and a multiple linear regression for the cost of the electromechanical equipment. These functions show a correlation between the construction costs and the population equivalent and enable us to understand it. The results show greater economic benefit in increasing wastewater treatment plants sizes serving a population equivalent of 5000 pe to 10,000 pe, while further increases are less beneficial.
Management of Banana Xanthomonas Wilt: Evidence from Impact of Adoption of Cultural Control Practices in Uganda
Authors: Kikulwe Enoch M. , Kyanjo Joseph Lule , Kato Edward , Ssali Reuben T. , Erima Rockefeller , Mpiira Samuel , Ocimati Walter , Tinzaara William , Kubiriba Jerome , Gotor Elisabetta , Stoian Dietmar , Karamura Eldad
Published: May 2019

Banana Xanthomonas Wilt (BXW) is an important emerging and non-curable infectious plant pathogen in sub-Saharan Africa that can cause up to 100% yield loss, negatively impacting sustainable access to food and income to more than 100 million banana farmers. This study disentangles adopters into partial and full adopters to investigate the factors that are relevant to sustain the adoption process of BXW control practices and quantifies the impact of adopting the practices. Data from a randomly selected sample of 1200 banana farmers in Uganda where the disease is endemic was used. A multinomial logit model was used to determine the factors affecting adoption of control practices and augmented inverse probability weighting was employed to estimate the impacts of adoption on banana productivity and sales. Results show that training a woman farmer and having diverse sources of information about BXW control practices increased adoption of the control practices and reduced the disease incidences. Farmers who adopted all the recommended control practices achieved significantly the highest values of banana production and sales. We conclude that improving information access through farmers’ preferred communication channels, having women-inclusive trainings, and a combination of cultural practices are effective ways for sustaining adoption of the control practices.
Chinese Financial Market Investors Attitudes toward Corporate Social Responsibility: Evidence from Mergers and Acquisitions
Authors: Zhang Fang , Li Minghui , Zhang Meilan
Published: May 2019

As China’s economic development has shifted from quantitative growth to qualitative improvement, stakeholders have enforced stricter corporate social responsibility (CSR) requirements for listed companies. However, few studies have focused on companies and CSR in such developing economies. We used the CSR scoring system from Hexun Finance’s website to group Chinese listed companies according to their CSR scores. By comparing the effects of merger and acquisition (M&A) announcements on different CSR scores, we found that, first, the average abnormal return (AAR) response time of the low-CSR acquirers group was eight trading days, much longer than that of the medium-CSR (three trading days) and the high-CSR group (four trading days). Second, from five trading days before, and 15 trading days after the announcement date, the cumulative AAR (CAAR) of the acquirers in the low-CSR group was 0.270, much higher than those in medium- and high-CSR groups. Third, after considering the CSR scores for the two years prior to the M&A and controlling for other factors affecting the M&A, the CSR performance of the above-mentioned M&As was still negatively correlated with the M&A announcement effect. This point to the need for further studying CSR and M&A announcement effects for Chinese companies.
GIS-Based Seismic Hazard Prediction System for Urban Earthquake Disaster Prevention Planning
Authors: Zhai Yongmei , Chen Shenglong , Ouyang Qianwen
Published: May 2019

It is of great significance to conduct seismic hazard prediction in mitigating the damage caused by earthquakes in urban area. In this study, a geographic information system (GIS)-based seismic hazard prediction system for urban earthquake disaster prevention planning is developed, incorporating structural vulnerability analysis, program development, and GIS. The system is integrated with proven building vulnerability analysis models, data search function, spatial analysis function, and plotting function. It realizes the batching and automation of seismic hazard prediction and the interactive visualization of predicted results. Finally, the system is applied to a test area and the results are compared with results from previous studies, the precision of which was improved because the construction time of the building was taken into consideration. Moreover, the system is of high intelligence and minimal manual intervention. It meets the operating requirements of non-professionals and provides a feasible technique and operating procedure for large-scale urban seismic hazard prediction. Above all, the system can provide data support and aid decision-making for the establishment and implementation of urban earthquake disaster prevention planning.
Culture Development for Sustainable SMEs: Toward a Behavioral Theory
Authors: Ketprapakorn Nuttasorn , Kantabutra Sooksan
Published: May 2019

The present study derives culture development practices among “sustainable” small and medium enterprises (SMEs)that adopt the Thai philosophy of the sufficiency economy. It adopts multiple data collection methods including non-participant observations made during visits to five “sustainable” enterprises, and references internal and published documents among other information about the case enterprises, including annual reports, previous studies about the companies and news reports. In-depth interview sessions were held with top management team members and employees, including CEOs or MDs, and division/functional heads. The “grounded theory” is adopted as an approach to analyze the data. The analysis reveals six emerging organizational culture development practices: identifying virtues, social and environmental responsibility and innovation as core values; leaders acting as models according to these values; growing their own managers to continue their corporate cultures; designing communication channels to emphasize the core values among employees; using the core values as criteria to recruit new employees; avoiding employee layoff to preserve the core values even in times of financial crisis. Limitations and future research directions to develop a behavioral theory of sustainability culture in organizational settings, as well as managerial implications are discussed.
Does Health-Oriented Tourism Contribute to Sustainable Mobility?
Authors: Schlemmer Philipp , Blank Cornelia , Bursa Bartosz , Mailer Markus , Schnitzer Martin
Published: May 2019

Previous research has concentrated on traffic and health-related effects in relation to arrival patterns (e.g., stress in connection with means of transport, travel distance, and time). However, tourist mobility behavior during a vacation and potential health-related associations as well as its correlation with physical activity habits and mobility patterns at home seems to have barely been examined. To address this research gap, the study at hand applied a mixed-method approach in three tourism destinations in Tyrol, Austria. The study examined tourists’ mobility as well as their physical activity at home and at the holiday destination. Results show that the preferred transport mode (arrival and on-site) is the private car, due to its flexibility and comfort. Hotel front desks, as the main information source, determine tourists’ behavioral aspects during a vacation. General mobility routines show differences between everyday life and holiday situations, and physical activity is important for the overall satisfaction of tourists, which proves to be more intense and frequent during a vacation than in everyday life. Seven percent of the tourists participating in the research stated that they had changed their daily mobility behavior after their return, with most of them walking or cycling more often. This study contributes to research in the field of sustainable tourist mobility and physical activity behavior and highlights the necessity for further specific analyses.
A Potential Risk of Increasing Cross-National Distance: Evidence from Less Sustainable Tax Policies
Authors: Gu Junjian
Published: May 2019

This study explores a possible risk of overseas investment in long cross-national distance host countries using the foreign direct investment (FDI) data in Japan. We expect that increasing cross-national distance would relate to the less sustainable tax policies by increasing the differences in economic, political, administrative, cultural, demographic, knowledge, and geographic perspectives, which enhance the motivation of tax aggressiveness and the likelihood of earnings management. Consistent with our expectations, we find that firms with longer cross-national distance are less likely to adopt sustainable tax policies. After some robust tests, our main findings remain unchanged. In additional analysis, we find the above relation is weakened when firms invest in a tax-haven country or have a high proportion of foreign ownership, while it is strengthened when firms meet an earnings benchmark. Overall, our results suggest the one risk of increasing cross-national distance between host country and home country is less sustainable tax policies.
Evaluating the Effects of Human Activity over the Last Decades on the Soil Organic Carbon Pool Using Satellite Imagery and GIS Techniques in the Nile Delta Area, Egypt
Authors: Mohamed Elsayed , Abu-hashim Mohamed , AbdelRahman Mohamed , Schütt Brigitta , Lasaponara Rosa
Published: May 2019

The study aims to clarify the relationship between soil organic carbon (SOC) and human activity under arid conditions, in the east area of the Nile Delta, Egypt. SOC is one of the critical factors in food production and plays an important role in the climate change because it affects the physio-chemical soil characteristics, plant growth, and contributes to sustainable development on global levels. For the purpose of our investigations, 120 soil samples (0–30 cm) were collected throughout different land uses and soil types of the study area. Multiple linear regressions (MLR) were used to investigate the spatiotemporal relationship of SOC, soil characteristics, and environmental factors. Remote sensing data acquired from Landsat 5 TM in July 1995 and operational land imager (OLI) in July 2018 were used to model SOC pool. The results revealed significant variations of soil organic carbon pool (SOCP) among different soil textures and land-uses. Soil with high clay content revealed an increase in the percentage of soil organic carbon, and had mean SOCP of 6.08 ± 1.91 Mg C ha−1, followed by clay loams and loamy soils. The higher values of SOCP were observed in the northern regions of the study area. The phenomenon is associated with the expansion of the human activity of initiating fish ponds that reflected higher values of SOC that were related to the organic additions used as nutrients for fish. Nevertheless, the SOC values decreased in southeast of the study area with the decrease of soil moisture contents and the increase in the heavy texture profiles. As a whole, our findings pointed out that the human factor has had a significant impact on the variation of soil organic carbon values in the Eastern Nile Delta from 1995 to 2018. As land use changes from agricultural activity to fish ponds, the SOCP significantly increased. The agriculture land-use revealed higher SOCP with 60.77 Mg C ha−1 in clay soils followed by fish ponds with 53.43 Mg C ha−1. The results also showed a decrease in SOCP values due to an increasing in land surface temperature (LST) thus highlighting that influence of temperature and ambient soil conditions linked to land-use changes have a marked impact on surface SOCP and C sequestration.
Does the Level of Environmental Uncertainty Matter in the Effect of Returnee CEO on Innovation? Evidence from Panel Threshold Analysis
Authors: Huang Weili , Ma Guangqi , Chen Xuemeng
Published: May 2019

This study applies a panel threshold regression model to reconcile the inconsistent findings about returnee chief executive officer (CEO) effects on enterprise innovation using the environmental uncertainty as the threshold variable and panel data from 187 publicly traded electronic firms in China for the period 2012–2016. The empirical results suggest that a significant double threshold effect does exist, showing an inverted-U correlation between returnee CEO and innovation. Specifically, a returnee CEO significantly promotes innovation at moderate levels of environmental uncertainty but significantly hinders innovation when the environmental uncertainty surpasses the larger threshold value, which contradicts much of the previous literature. This research enriches the scholarship on returnee CEOs and lays a theoretical foundation that firms can use in corporate governance. If firms pay more attention to environmental uncertainty while formulating new CEO introduction policies, substantial innovation ability can be improved at moderate levels of environmental uncertainty.
Understanding Consumer E-Waste Recycling Behavior: Introducing a New Economic Incentive to Increase the Collection Rates
Authors: Shevchenko Tetiana , Laitala Kirsi , Danko Yuriy
Published: May 2019

Consumer electronics are made of a wide range of materials, including precious metals and critical minerals with limited global reserves. Ensuring the recycling of these materials is essential for future use, especially since many renewable energy solutions are based on them. In addition, improper end-of-life treatments of these products cause harm to the environment and human health. This study explores the incentives that have been used to increase consumer collection rates for end-of-life electrical and electronic equipment (EoL EEE). Based on extensive global literature reviews, we propose an alternative to existing consumer incentives. The research suggests that implementing an economic incentive based on the electronic bonus card system (EBCS) has several benefits compared to existing incentives. It compensates the consumers for the transaction costs of proper collection and satisfies the consumer perception of EoL EEE as having a residual value. However, application of the EBCS motivation technology will require the cooperation of various stakeholders, including electronics producers and national and international authorities.
Transforming Municipal Solid Waste into Construction Materials
Authors: Sofi Massoud , Sabri Ylias , Zhou Zhiyuan , Mendis Priyan
Published: May 2019

Rapid urbanisation and the associated infrastructure development are creating a deficit of conventional construction materials and straining the natural resources. On the other hand, municipal solid waste (MSW) disposal poses a serious environmental problem. Landfilling of MSW is both costly and polluting. Incineration of MSW to generate energy is a commonly adopted approach. However, there are concerns associated with micro pollutants emitted from the combustion process. The carbon footprint of the process and the environmental cost–benefit balancing are disputable. There is clearly a need to adopt cost-effective alternatives to treat MSW. This paper proposes the potential application of “treated” MSW as an ingredient for construction materials. The treatment process involves placing MSW in an autoclave at 150 °C with 5 bars (0.5 MPa), followed by the separation of metals, plastics and glass for recycling purposes. The end-product, which is a semi-organic mixture (referred to as ‘biomass’), is passed through a vortex-oscillation system, which makes it more uniform as a material. Compressive testing of Portland cement-based pastes containing 10% and 15% biomass shows consistency in the results, demonstrating the potential use of biomass in construction materials.
Joining Historic Cities to the Global World: Feasibility or Fantasy?
Authors: Shirvani Dastgerdi Ahmadreza , De Luca Giuseppe
Published: May 2019

Given the globalisation and free movement of capital and people, global cities compete with others not only as tourist destinations but also for the attraction of investors, skilled labour and well-educated citizens. In this research, the image of the historic city of Florence is investigated from the perspective of tourists and residents to assess the feasibility of joining historic cities to the global world. The sample size included 384 people who were randomly selected in the historic centre of Florence and answered the research questionnaire. The data was then analysed by descriptive statistics and logistic regression test. The findings show that although appropriate environmental qualities have made Florence highly successful in attracting tourists, what can promote the sustainability level of this historic city in the globalisation era is the organisation of urban planning in order to gain a part of global economic and human capital by creating the precise and unique image of the city.
QoS Enabled Layered Based Clustering for Reactive Flooding in the Internet of Things
Authors: Khan Fawad Ali , Noor Rafidah Md , Mat Kiah Miss Laiha , Noor Noorzaily Mohd , Altowaijri Saleh M. , Rahman Atiq Ur
Published: May 2019

The Internet of Things has gained substantial attention over the last few years, because of connecting daily things in a wide range of application and domains. A large number of sensors require bandwidth and network resources to give-and-take queries among a heterogeneous IoT network. Network flooding is a key questioning strategy for successful exchange of queries. However, the risk of the original flooding is prone to unwanted and redundant network queries which may lead to heavy network traffic. Redundant, unwanted, and flooded queries are major causes of inefficient utilization of resources. IoT devices consume more energy and high computational time. More queries leads to consumption of more bandwidth, cost, and miserable QoS. Current existing approaches focused primarily on how to speed up the basic routing for IoT devices. However, solutions for flooding are not being addressed. In this paper, we propose a cluster-based flooding (CBF) as an interoperable solution for network and sensor layer devices which is also capable minimizing the energy consumption, cost, network flooding, identifying, and eliminating of redundant flooding queries using query control mechanisms. The proposed CBF divides the network into different clusters, local queries for information are proactively maintained by the intralayer cluster (IALC), while the interlayer cluster (IELC) is responsible for reactively obtain the routing queries to the destinations outside the cluster. CBF is a hybrid approach, having the potential to be more efficient against traditional schemes in term of query traffic generation. However, in the absence of appropriate redundant query detection and termination techniques, the CBF may generate more control traffic compared to the standard flooding techniques. In this research work, we used Cooja simulator to evaluate the performance of the proposed CBF. According to the simulation results the proposed technique has superiority in term of traffic delay, QoS/throughput, and energy consumption, under various performance metrics compared with traditional flooding and state of the art.
Buffer Occupancy-Based Transport to Reduce Flow Completion Time of Short Flows in Data Center Networks
Authors: Ahmed Hasnain , Arshad Muhammad Junaid
Published: May 2019

Today’s data centers host a variety of different applications that impose specific requirements for their flows. Applications that generate short flows are usually latency sensitive; they require their flows to be completed as fast as possible. Short flows suffer to quickly increase their sending rate due to the existing long flows occupying most of the available capacity. This problem is caused due to the slow convergence of the current data center transport protocols. In this paper, we present a buffer occupancy-based transport protocol (BOTCP) to reduce flow completion time of short flows. BOTCP consists of two parts: (i) A novel buffer occupancy-based congestion signal, and (ii) a congestion control scheme that uses the congestion signal to reduce flow completion time of short flows. The proposed buffer occupancy-based congestion signal gives a precise measure of congestion. The congestion control scheme makes a differentiated treatment of short and long flows to reduce flow completion time of short flows. The results show that BOTCP significantly improves flow completion time of short flows over the existing transport protocols in data center networks.
Cadmium Sources and Toxicity
Authors: Satarug Soisungwan
Published: May 2019

This special issue of Toxics, Cadmium (Cd) sources and toxicity, consists of one comprehensive review [...]
The Associations between Immunological Reactivity to the Haptenation of Unconjugated Bisphenol A to Albumin and Protein Disulfide Isomerase with Alpha-Synuclein Antibodies
Authors: Kharrazian Datis , Herbert Martha , Vojdani Aristo
Published: May 2019

Patients with Parkinson’s disease (PD) have increased susceptibility to bisphenol A (BPA) exposure since they have an impaired biotransformation capacity to metabolize BPA. PD subjects have reduced levels of conjugated BPA compared to controls. Reduced ability to conjugate BPA provides increased opportunity for unconjugated BPA to bind to albumin in human serum and protein disulfide isomerase on neurons. Once unconjugated BPA binds to proteins, it changes the allosteric structure of the newly configured protein leading to protein misfolding and the ability of the newly configured protein to act as a neoantigen. Once this neoantigen is formed, the immune system produces antibodies against it. The goal of our research was to investigate associations between unconjugated BPA bound to human serum albumin (BPA–HSA) antibodies and alpha-synuclein antibodies and between Protein Disulfide Isomerase (PDI) antibodies and alpha-synuclein antibodies. Enzyme–linked immunosorbent assay was used to determine the occurrences of alpha-synuclein antibodies, antibodies to BPA–HSA adducts, and PDI antibodies in the sera of blood donors. Subjects that exhibited high levels of unconjugated BPA–HSA antibodies or PDI antibodies had correlations and substantial risk for also exhibiting high levels of alpha-synuclein antibodies (p < 0.0001). We conclude that there are significant associations and risks between antibodies to BPA–HSA adducts and PDI antibodies for developing alpha-synuclein antibodies.
Radiocarbon Tracers in Toxicology and Medicine: Recent Advances in Technology and Science
Authors: Malfatti Michael A. , Buchholz Bruce A. , Enright Heather A. , Stewart Benjamin J. , Ognibene Ted J. , McCartt A. Daniel , Loots Gabriela G. , Zimmermann Maike , Scharadin Tiffany M. , Cimino George D. , Jonas Brian A. , Pan Chong-Xian , Bench Graham , Henderson Paul T. , Turteltaub Kenneth W.
Published: May 2019

This review summarizes recent developments in radiocarbon tracer technology and applications. Technologies covered include accelerator mass spectrometry (AMS), including conversion of samples to graphite, and rapid combustion to carbon dioxide to enable direct liquid sample analysis, coupling to HPLC for real-time AMS analysis, and combined molecular mass spectrometry and AMS for analyte identification and quantitation. Laser-based alternatives, such as cavity ring down spectrometry, are emerging to enable lower cost, higher throughput measurements of biological samples. Applications covered include radiocarbon dating, use of environmental atomic bomb pulse radiocarbon content for cell and protein age determination and turnover studies, and carbon source identification. Low dose toxicology applications reviewed include studies of naphthalene-DNA adduct formation, benzo[a]pyrene pharmacokinetics in humans, and triclocarban exposure and risk assessment. Cancer-related studies covered include the use of radiocarbon-labeled cells for better defining mechanisms of metastasis and the use of drug-DNA adducts as predictive biomarkers of response to chemotherapy.
Development of an Indirect Quantitation Method to Assess Ichthyotoxic B-Type Prymnesins from Prymnesium parvum
Authors: Svenssen Daniel Killerup , Binzer Sofie Bjørnholt , Medić Nikola , Hansen Per Juel , Larsen Thomas Ostenfeld , Varga Elisabeth
Published: May 2019

Harmful algal blooms of Prymnesium parvum have recurrently been associated with the killing of fish. The causative ichthyotoxic agents of this haptophyte are believed to be prymnesins, a group of supersized ladder-frame polyether compounds currently divided into three types. Here, the development of a quantitative method to assess the molar sum of prymnesins in water samples and in algal biomass is reported. The method is based on the derivatization of the primary amine group and subsequent fluorescence detection using external calibrants. The presence of prymnesins in the underivatized sample should be confirmed by liquid chromatography mass spectrometry. The method is currently only partly applicable to water samples due to the low amounts that are present. The growth and cellular toxin content of two B-type producing strains were monitored in batch cultures eventually limited by an elevated pH. The cellular toxin contents varied by a factor of ~2.5 throughout the growth cycle, with the highest amounts found in the exponential growth phase and the lowest in the stationary growth/death phases. The strain K-0081 contained ~5 times more toxin than K-0374. Further investigations showed that the majority of prymnesins were associated with the biomass (89% ± 7%). This study provides the basis for further investigations into the toxicity and production of prymnesins.
Fusarium Mycotoxins Stability during the Malting and Brewing Processes
Authors: Piacentini Karim C. , Běláková Sylvie , Benešová Karolína , Pernica Marek , Savi Geovana D. , Rocha Liliana O. , Hartman Ivo , Čáslavský Josef , Corrêa Benedito
Published: May 2019

Mycotoxins are widely studied by many research groups in all aspects, but the stability of these compounds needs further research for clarification. The objective of this study is to evaluate deoxynivalenol and zearalenone stability during all steps of the malting and brewing processes. The levels of these compounds decreased significantly during the production process (barley to beer). During the malting process, the DON levels decreased significantly in the steeping, germination, and malting steps (62%, 51.5%, and 68%, respectively). Considering ZEN, when the levels were compared between barley and the last step of the process, a significant decrease was observed. Most of the mycotoxins produced were transferred to the rootlets and spent grains, which is advantageous considering the final product. Furthermore, the mycotoxin dietary intake estimation was included in this study. The results proved that if the concentrations of target mycotoxins in raw material are under the limits established by the regulations, the levels decrease during the malting and brewing processes and make the beer secure for consumers. The quality of the five commodities involved in the beer process plays a decisive role in the creation of a safe final product.
Comparison of Apoptosis and Autophagy in Human Chondrocytes Induced by the T-2 and HT-2 Toxins
Authors: Yu Fang-Fang , Lin Xia-Lu , Wang Xi , Ping Zhi-Guang , Guo Xiong
Published: May 2019

In this report, we have investigated the apoptosis and autophagy of chondrocytes induced by the T-2 and HT-2 toxins. The viability of chondrocytes was measured by the MTT assay. Malondialdehyde (MDA) and superoxide dismutase (SOD) kits were used to measure the oxidative stress of chondrocytes. The apoptosis of chondrocytes was measured using flow cytometry. Hoechst 33258 and MDC staining agents were introduced to analyze apoptosis and autophagy induction in chondrocytes, respectively. Protein expression of Bax, caspase-9, caspase-3, and Beclin1 was examined by western blotting analysis. The T-2 and HT-2 toxins significantly decreased the viability of chondrocytes in a time-dependent manner. The level of oxidative stress in chondrocytes induced by the T-2 toxin was significantly higher when compared with that of the HT-2 toxin. The apoptosis rate of chondrocytes induced by the T-2 toxin increased from 3.26 ± 1.03%, 18.38 ± 1.28%, 34.5 ± 1.40% to 49.67 ± 5.31%, whereas apoptosis rate of chondrocytes induced by the HT-2 toxin increased from 3.82 ± 1.03%, 11.61 ± 1.27%, 25.72 ± 2.95% to 36.28 ± 2.81% in 48 h incubation time. Hoechst 33258 staining confirmed that apoptosis of chondrocytes induced by the T-2 toxin was significantly higher than that observed when the chondrocytes were incubated with the HT-2 toxin. MDC staining revealed that the autophagy rate of chondrocytes induced by the T-2 toxin increased from 6.38% to 63.02%, whereas this rate induced by the HT-2 toxin changed from 6.08% to 53.33%. The expression levels of apoptosis and autophagy related proteins, Bax, caspase-9, caspase-3, and Beclin1 in chondrocytes induced by the T-2 toxin were significantly higher when compared with those levels induced by the HT-2 toxin.
Schistosomiasis Elimination: Beginning of the End or a Continued March on a Trodden Path
Authors: Bergquist Robert , Gray Darren J.
Published: May 2019

In spite of spectacular progress towards the goal of elimination of schistosomiasis, particularly in China but also in other areas, research gaps and outstanding issues remain. Although expectations of achieving elimination of this disease have never been greater, all constraints have not been swept aside. Indeed, there are some formidable obstacles, such as insufficient amounts of drugs to treat everybody and still limited use of high-sensitive diagnostic techniques, both for the definitive and the intermediate hosts, which indicate that prevalence is considerably underrated in well-controlled areas. Elimination will be difficult to achieve without a broad approach, including a stronger focus on transmission, better diagnostics and the establishment of a reliable survey system activating a rapid response when called for. Importantly, awareness of the crucial importance of transmission has been revived resulting in renewed interest in snail control together with more emphasis on health education and sanitation. The papers collected in this special issue entitled ‘Prospects for Schistosomiasis Elimination’ reflect these issues and we are particularly pleased to note that some also discuss the crucial question when to declare a country free of schistosomiasis and present techniques that together create an approach that can show unequivocally when interruption of transmission has been achieved.
Equation of State of a Magnetized Dense Neutron System
Authors: Ferrer Efrain J. , Hackebill Aric
Published: May 2019

We discuss how a magnetic field can affect the equation of state of a many-particle neutron system. We show that, due to the anisotropy in the pressures, the pressure transverse to the magnetic field direction increases with the magnetic field, while the one along the field direction decreases. We also show that in this medium there exists a significant negative field-dependent contribution associated with the vacuum pressure. This negative pressure demands a neutron density sufficiently high (corresponding to a baryonic chemical potential of μ = 2.25 GeV) to produce the necessary positive matter pressure that can compensate for the gravitational pull. The decrease of the parallel pressure with the field limits the maximum magnetic field to a value of the order of 10 18 G, where the pressure decays to zero. We show that the combination of all these effects produces an insignificant variation of the system equation of state. We also found that this neutron system exhibits paramagnetic behavior expressed by the Curie’s law in the high-temperature regime. The reported results may be of interest for the astrophysics of compact objects such as magnetars, which are endowed with substantial magnetic fields.
Innovative Arrangements between Public and Private Actors in Affordable Housing Provision: Examples from Austria, England and Italy
Authors: van Bortel Gerard , Gruis Vincent
Published: May 2019

Affordable housing is increasingly developed, financed and managed by a mix of state, third-sector, market and community actors. This has led to the emergence of various hybrid governance and finance arrangements. This development can be seen as part of a general long-term neoliberal trend in government policies, and social, cultural and economic developments. It is therefore likely that the hybridity and variety of governance and finance of affordable housing will continue to grow. This article discusses innovative hybrid arrangements from Austria, England and Italy, in which governments, private and non-profit actors collaborate to increase the supply of affordable housing. These cases illustrate how the provision of affordable housing in a neoliberal context can benefit from the involvement of market actors and communities. Nevertheless, they also show that governments continue to play a crucial role in initiating and facilitating these arrangements.
Interaction between Two Iridovirus Core Proteins and Their Effects on Ranavirus (RGV) Replication in Cells from Different Species
Authors: Zeng Xiao-Tao , Zhang Qi-Ya
Published: May 2019

The two putative proteins RGV-63R and RGV-91R encoded by Rana grylio virus (RGV) are DNA polymerase and proliferating cell nuclear antigen (PCNA) respectively, and are core proteins of iridoviruses. Here, the interaction between RGV-63R and RGV-91R was detected by a yeast two-hybrid (Y2H) assay and further confirmed by co-immunoprecipitation (co-IP) assays. Subsequently, RGV-63R or RGV-91R were expressed alone or co-expressed in two kinds of aquatic animal cells including amphibian Chinese giant salamander thymus cells (GSTCs) and fish Epithelioma papulosum cyprinid cells (EPCs) to investigate their localizations and effects on RGV genome replication. The results showed that their localizations in the two kinds of cells are consistent. RGV-63R localized in the cytoplasm, while RGV-91R localized in the nucleus. However, when co-expressed, RGV-63R localized in both the cytoplasm and the nucleus, and colocalized with RGV-91R in the nucleus. 91R△NLS represents the RGV-91R deleting nuclear localization signal, which is localized in the cytoplasm and colocalized with RGV-63R in the cytoplasm. qPCR analysis revealed that sole expression and co-expression of the two proteins in the cells of two species significantly promoted RGV genome replication, while varying degrees of viral genome replication levels may be linked to the cell types. This study provides novel molecular evidence for ranavirus cross-species infection and replication.