bluuebunny/crossref_metadata_2025 huggingface dataset:
Identification and validation of autophagy-related genes and exploration of their relationship with disease severity in chronic rhinosinusitis with nasal polyps
Authors: Zi Jiajia , Yu Longgang , Wang Lin , Yan Xudong , Li Danyang , Du Xiaoyun , Zhang Jisheng , Jiang Yan
Published: September 2024

Background:

Chronic rhinosinusitis with nasal polyps (CRSwNP) pathogenesis might be impacted by autophagy. Nevertheless, autophagy-related gene utilization as a disease indicator about the course of CRSwNP has yet to be elucidated.

Objective:

This investigation aimed at discovering pivotal molecules related to autophagy to identify potential treatment targets for CRSwNP.

Methods:

The dataset GSE136825 was obtained via the Gene Expression Omnibus (GEO) database, and afterward, differentially expressed genes (DEGs) analysis linked to autophagy was employed via the R software. A comprehensive examination of autophagy-related DEGs was conducted using functional analytic techniques. The utilization of the protein-protein interaction (PPI) network facilitated hub gene identification. Quantitative real-time polymerase chain reaction (qRT-PCR), western blot, and immunohistochemistry staining techniques were performed to validate the expression levels of the central genes in clinical samples. Correlation analysis was performed to examine the correlation between hub genes and disease severity parameters.

Results:

A comprehensive set of 86 autophagy-related DEGs were discovered. The functional enrichment analysis of autophagy-related DEGs revealed the identification of enrichment terms involved with the autophagy process. The results obtained from the PPI analysis suggest that there was interaction among the autophagy-related genes. The qRT-PCR, immunohistochemistry staining, and western blot techniques yielded results, demonstrated that CXCR4, HMOX1, and SPP1 expression levels in CRSwNP agreed with the bioinformatics analysis of the dataset. Furthermore, a favorable association between CXCR4, HMOX1, and SPP1 expression levels with illness severity indicators was found.

Conclusion:

Bioinformatics analysis yielded 86 autophagy-related DEGs in CRSwNP. CXCR4, HMOX1, and SPP1 regulation of autophagy has been confirmed in CRSwNP progression and pathogenesis.
Optimalisasi Partisipasi Siswa melalui Pembelajaran Berbasis Diskusi: Studi Kasus di SMP Bilingual Terpadu Junwangi Krian Sidoarjo
Authors: Adi Muhammad Iqbal Fikri , Rahmah Nadia Wulida , Farhan Farhan
Published: September 2024

This study examines the implementation of the Discussion-Based Learning Model in increasing the active participation of students at the Integrated Bilingual Junior High School, Junwangi Village, Krian Sidoarjo. This research aims to provide guidance for teachers in choosing an effective learning model, so that it makes it easier for students to understand the material being taught. The research method used is observation and interviews to collect data related to student activity. The observation results showed that students dared to express their opinions, enthusiastically answered questions or quizzes from teachers, and actively asked questions to teachers or fellow students when there was material that was poorly understood. In addition, students also participate in group discussions according to the teacher's direction. The implementation of this model shows that the discussion method is effective in increasing student participation and preparing teachers in managing discussions. Through the discussion model, students' interest in learning increases and the learning process becomes more creative
Management Strategies of Cesarean Section Ectopic Pregnancy: A Case Report
Authors: Daley Hannah E. , Hansen Ava R. , Raju Priyanka , Buerger Jonathan
Published: September 2024

Introduction: Cesarean scar ectopic pregnancy is a rare form of pregnancy with potential life-threatening complications such as severe hemorrhage, uterine rupture, and emergency hysterectomy Currently, there is no consensus regarding a standardized treatment algorithm for this specific variant of ectopic pregnancies. Case Description: This case describes a 28-year-old female with history of two prior cesarean sections who was diagnosed with cesarean section scar ectopic pregnancy. Initial management with intramuscular methotrexate was unsuccessful in the setting of inadequate decrease in β-hCG level. The patient ultimately underwent surgical management with dilation and suction evacuation under ultrasound guidance for removal of the ectopic pregnancy. Following surgery, the patient continued to have an appropriate downward trend of β-hCG, indicating a successful result of the procedure. Discussion: The objective of this case report is to review this case of cesarean scar ectopic pregnancy, identify various treatment modalities for this condition, and analyze their success rates and possible reasons for failure based on literature review. We conclude that the wide use of methotrexate for cesarean section ectopic pregnancies should be reconsidered and minimally invasive techniques such as the double-balloon catheter procedure be further researched.
Catastrophic Spontaneous Uterine and Bladder Rupture in an Unscarred Uterus
Authors: Hoskins Nathanael N. , Brandt Kathryn , Peterson Tory
Published: September 2024

Introduction: Uterine rupture during pregnancy is a rare event which can be life-threatening for both the patient and the fetus. This case report describes a rare complication of uterine rupture which ultimately required a hysterectomy and extensive urologic reconstruction. Case Description: A 36-year-old patient presented to the hospital after term pre-labor rupture of membranes. The patient underwent induction of labor which ultimately resulted in a uterine rupture in an unscarred uterus. The rupture extended into the posterior bladder wall, right ureter, urethra, and anterior vaginal wall, resulting in a vesicovaginal fistula. The patient required a cesarean hysterectomy due to the uterine damage. Cystorrhaphy with right percutaneous nephrostomy tube and suprapubic catheter placement were performed due to the extensive urologic sequelae. Months later, the patient underwent ureteroneocystostomy for definitive urologic management. Discussion: Bladder rupture is a rare complication of uterine rupture and can occur in an unscarred uterus. Intrapartum bladder rupture should be considered in patients who develop gross hematuria or anterior vaginal wall laceration in the setting of uterine rupture. Maternal morbidity and mortality due to uterine rupture is decreased when care is provided at a tertiary referral or trauma center. This should be taken into consideration when planning deliveries with an increased risk of uterine rupture. Furthermore, providers performing vaginal deliveries should be aware of this rare complication to optimize maternal and neonatal outcomes.
The "Pros" of Probiotics: A Review of Probiotics Place in Therapy
Authors: Maberry Kelley , Nguyen Hanh , Quinter Connor , Magalona Justine
Published: September 2024

As different probiotic supplements become increasingly seen in the market, questions regarding their use for gut health from patients rises as well. Because these supplements do not require FDA approval, their safety and efficacy is often unknown and limited research available poses an even greater challenge for healthcare providers when prompted with questions regarding their use. This article summarizes evidence-based recommendations provided by the American Gastroenterological Association (AGA) and the World Gastroenterology Organization (WGO). Of the conditions discussed, supportive evidence on the use of probiotics is mostly seen in the prevention of C. diff associated diarrhea, prevention of antibiotic associated diarrhea and treatment of IBS. Of the millions of different strains available, the recurring genus seen across multiple disease states is Lactobacillus. It is most known that probiotics serve as a source of “good” bacteria, but these supplements may pose a threat in certain patient populations and require careful consideration between patients and providers before starting.
Language Shift and Maintenance of Chittagonian Language towards Standard Bengali Language
Authors: Barua Akash
Published: September 2024

This study aims to investigate which form of Bengali, Chittagonian or Standard, is most commonly used by native Chittagong speakers in their everyday lives. In other words, it seeks to determine if there is a language shift and the maintenance of Chittagonian amid Standard Bengali's dominance. The native speakers of Chittagonian from 19 distinct locations in the Chittagong district participated in the study. The study's time frame was from May 2022 to August 2022, and 117 respondents were interviewed using a formulated questionnaire. Descriptive statistics is used for quantitative analysis. The study's findings demonstrate that language usage preferences vary depending on the context. According to the results, most respondents are comfortable using Chittagonian with family and in their neighborhoods. In contrast, Standard Bengali is widely used in education and public settings because it effectively conveys information. The study concluded that as most of Chittagong's local people continue to speak Chittagonian, it is not at imminent risk of being completely displaced. Although the Chittagonian language is shifting in education and public places, the transition is gradual, and the language is still safe. It indicates that Chittagonian is preserved by locals and will continue to be used for generations to come.
BSN: First photometric light curve analysis of two W-type contactbinary systems OP Boo and V0511 Cam
Authors: Poro A. , Tanriver M. , Keskin A. , Bulut A. , Rabieefar S , Gharghabi M. M. , Walter F. , Holy, S. S. , Holy S.
Published: September 2024

This study presented the first light curve analysis of the OP Boo and V0511 Cam binary stars, which was conducted in the frame of the Binary Systems of South and North (BSN) Project. Photometric ground-based observations were conducted with standard filters at two observatories in the Czech Republic. We computed a new ephemeris for each of the systems using our extracted times of minima, TESS data, and additional literature. Linear fits for O-C diagrams of both systems were considered using the Markov Chain Monte Carlo (MCMC) method. The light curves were analyzed using the Wilson-Devinney (WD) binary code combined with the Monte Carlo (MC) simulation. The light curve solutions of both target systems required a cold starspot. The absolute parameters of the systems were calculated by using a P - M parameter relationship. The positions of the systems were also depicted on the Hertzsprung-Russell (HR), P - L, logMtot - logJ0, and T - M diagrams. The hotter component in both systems is determined to be a more massive star. Therefore, it can be concluded that both systems are W-type contact binary systems.
A Neural Network Analysis of Accounting Variables and Stock Price: The Case of Real Estate Companies in the Philippines
Authors: Lelis Christhoffer P , Muega Neil Patrick S
Published: September 2024

This research examines the importance of various accounting variables in predicting stock price changes for the top three real estate companies on the 2024 Philippine Stock Exchange. The study uses artificial neural network (ANN) analysis to focus on the current ratio, return on assets, return on equity, net profit margin, operating profit margin, and debt-to-equity ratio. Quarterly financial reports and stock prices from 2018 to 2023 were analyzed with a feedforward back-propagation ANN model in SPSS 25. Results show that the net profit margin is the most significant predictor of stock prices, highlighting profitability as crucial. The operating profit margin is significant for Mega World Corporation, while the current ratio is critical for SM Prime Holdings. The debt-to-equity ratio is moderately important across all companies. These findings emphasize the varied impact of profitability, operational efficiency, leverage, and liquidity on stock prices, aiding investment decisions and strategic planning.
Improving the social emotional abilities of children aged 5-6 years through market day activities at RA Tarbiyatul Akhlaq Wedoroanom
Authors: Fauziyah Nabiatul Luaili , Siti Mufarrochah
Published: September 2024

Social emotional development of children aged 5-6 years includes three aspects of indicators namely self-awareness, attitude of responsibility and prosocial attitude. In this social-emotional development, the proximate attitude has nine sub-indicators in it. This RA Tarbiyatul Akhlaq institution has a background of students who are not optimal in their social emotional development, especially in their prosocial attitudes. For this reason, this Market Day activity is one of the playing activities by selling which can support increasing social emotional development. The research method used in this study is a type of qualitative research with a descriptive approach. The data collection techniques used were participant observation, in-depth interviews and documentation. While the data analysis uses the method of technical triangulation, which combines data obtained from observation, interview and documentation methods. Based on the research conducted by the researchers, it can be concluded that with the Market Day activity, the social emotional development of children aged 5-6 years can develop as expected, but there are some children who are still starting to develop, this is because there are several factors inhibiting their development.
VACINAÇÃO CONTRA A POLIOMIELITE NA REGIÃO NORTE: UMA ANÁLISE COMPARATIVA DE 2018 A 2023
Authors: Medeiros Gabriele Caires de , Conceição Matilde da Silva , Sousa Geane Amorim de , Oliveira Elizângela Barbosa de Lima , Braga Iara Pereira Canal
Published: September 2024

Introdução: A poliomielite é uma doença imunoprevenível, porém, nos últimos anos tem apresentado queda na procura por imunização e na cobertura vacinal. Objetivo: Analisar o número de doses aplicadas e a cobertura vacinal contra poliomielite na região Norte, no período de 2018 a 2023. Método: Trata-se de um estudo transversal, quantitativo, epidemiológico, de série histórica, por meio de dados do Departamento de Informática do Sistema Único de Saúde (DATASUS). Resultados: Foram registradas 6.416.284 doses aplicadas da vacina contra a poliomielite na região norte, tendência a manutenção no número de doses no biênio 2018-2019, com queda na quantidade de vacinas aplicada durante os anos de 2020 e 2021, com redução de 244.828 entre 2019 e 2020. Os estados do Amapá, Pará e Acre foram responsáveis pela menor cobertura da região, com 44.03%, 50.77%, 55.43% respectivamente. A vacina mais aplicada foi a VIP e < 1 ano foram os mais imunizados. Conclusão: A paralisia infantil é um problema de saúde pública, cujo declínio na vacinação acarreta risco de reemergência do vírus, e por conseguinte de novos casos. Destarte, é importante continuar monitorando a evolução desses dados, e, garantir o restabelecimento da cobertura vacinal adequada na região.
Microbiome Dynamics and Strategic Management Strategies: Exploring Synergies between Integrative Medicine Modalities and Microbial Balance
Authors: Abdulsalam Mustapha , Hamisu Aisha Abba , Ahmad Aisha Musa , Wakili Fatima Balarabe , Annu Fatima Sulaiman , Garba Maryam Murtala
Published: September 2024

The relationship between human health and the intricate microbial communities residing within the body has garnered considerable attention in recent years. This study delves into the compelling interplay between microbiome dynamics and strategic management strategies within the context of integrative medicine. The genesis of the problem lies in the recognition that the human microbiome exerts profound influences on various physiological processes and contributes significantly to overall well-being. However, managing this microbial balance presents a complex challenge, especially when integrating diverse approaches from integrative medicine modalities such as acupuncture, herbal medicine, nutrition, and meditation. The objective of this study is to explore the synergies between integrative medicine practices and microbial balance management to enhance therapeutic outcomes. It underscores the pivotal role of the microbiome in the efficacy of integrative medicine modalities, elucidating how interventions can influence microbial communities and vice versa. As a result of the analysis, strategic management strategies emerge as pivotal tools in optimizing the convergence of integrative medicine practices and microbial balance. This study recommends a holistic and personalized approach that integrates various modalities while considering the dynamic nature of the microbiome. It concludes that acknowledging and managing the microbiome's impact on integrative therapies can potentially revolutionize healthcare. More so, while this study sheds light on the promising intersection of microbiome dynamics and strategic management strategies within integrative medicine, it acknowledges limitations in the current understanding of this complex relationship. Nonetheless, this exploration opens avenues for further research, innovation, and a more integrated approach to holistic healthcare
Microbial Magic: Decoding the Impact of Hypoxia on Exercise Physiology through Microbiota Dynamics
Authors: Abdulsalam Mustapha , Natour Sarah , Rabiu Iman Bala , Abdulazeez Muhammed
Published: September 2024

This study explores the intricate interplay between microbiota, hypoxia-induced physiological adaptations, and exercise physiology. In a time where understanding the nuanced connections between microbial communities and human health is gaining prominence. The present study fills a significant research gap by exploring the processes by which microbiota modification alters physiological responses to hypoxic environments during exercise. The objective of this study is to disentangle the microbial metabolic discourse that unfurls in the context of hypoxia-induced physiological adaptations, thereby shedding light on potential avenues for enhancing exercise performance and optimizing health outcomes. This study presents a synthesis of existing knowledge to discern significant patterns and insights. This study divulges the multifaceted relationships between microbiota composition, host metabolism, immune responses, and exercise-induced hypoxic adaptations by analyzing the existing work. The findings of this analysis highlight the crucial job of microbiota in modulating host responses to hypoxia, impacting metabolic pathways, oxygen transport, and cellular signaling. This study contributes to the advancing field of exercise physiology by elucidating the intricate connections between microbial communities and hypoxia-induced physiological adaptations. It emphasizes the significance of considering the microbiota as an integral component of the exercise response, opening up new avenues for innovative strategies to optimize exercise outcomes.
أثر اختلاف نمط عرض كائنات ثلاثية الأبعاد التفاعلية بالواقع المعزز (منفصل- مدمج) في بيئة التعلم المدمج على تنمية مهارات التفكير البصري في مقرر الرياضيات لدى طالبات المرحلة الثانوية
Authors: السعوي نوره محمد علي , المجيد أشرف عويس محمد عبد
Published: September 2024

هدف هذا البحث إلى الكشف عن أثر اختلاف نمط عرض كائنات ثلاثية الأبعاد التفاعلية بالواقع المعزز (منفصل- مدمج) في بيئة التعلم المدمج على تنمية مهارات التفكير البصري في مقرر الرياضيات لدى طالبات المرحلة الثانوية، وتكونت عينة البحث من (60) طالبة من طالبات الصف الثالث ثانوي بمدينة بريدة، تم تقسيمهن عشوائيًا إلى مجموعتين تجريبيتين، ضمت كل مجموعة (30) طالبة، درست كل مجموعة بأحد أنماط عرض الكائنات ثلاثية الأبعاد (منفصل- مدمج) التفاعلية بالواقع المعزز في بيئة التعلم المدمج، وتبنى البحث منهج البحوث التطويرية Development Research، التي يتكامل فيها ثلاثة مناهج هي: المنهج الوصفي ومنهج التطوير المنظومي بالإضافة إلى المنهج شبه التجريبي، وتم تطوير أداة اختبار تقيس مهارات التفكير البصري، وكشفت نتائج التطبيق البعدي عن وجود أثر إيجابي دال إحصائيًا عند مستوى الدلالة (α ≤ 0.05) لاختلاف نمط عرض كائنات ثلاثية الأبعاد التفاعلية بالواقع المعزز (منفصل - مدمج) في بيئة التعلم المدمج على تنمية مهارات التفكير البصري لصالح المجموعة التجريبية الأولى بنمط العرض المنفصل، وذلك بحجم تأثير مرتفع، وفي ضوء هذه النتائج خرج البحث بعدة توصيات أهمها: الاستفادة من أنماط عرض الكائنات ثلاثية الأبعاد التفاعلية بالواقع المعزز (منفصل- مدمج) في بيئة التعلم المدمج لتنمية مهارات التفكير البصري، والتنوع في بناء الأنشطة التعليمية باستخدام أنماط العرض ثلاثية الأبعاد التفاعلية ضمن بيئات الواقع المعزز.
حماية الشهود في ضوء المعاهدات والاتفاقيات الدولية (دراسة موضوعية)
Authors: الغياثن عبدالله حمد , صمودين ستي عائشة بنت , حسين محمد النور حصيري بن مات , سماح محماتيودنج بن
Published: September 2024

تناولت الدراسة حماية الشهود في ضوء المعاهدات والاتفاقيات الدولية، وانطلقت الدراسة من إشكالية ما يتعرض له الشهود من مخاطر نتيجة الإدلاء بالشهادة، وذلك بتهديدهم حتى يمتنعوا عن ذلك، أو بتعريضهم للخطر أو حتى القتل من أجل ذلك، وهدفت الدراسة بيان مدى الحماية الموضوعية للشهود في الاتفاقيات والمعاهدات الدولية، ومعرفة مظاهر الحماية الإجرائية للشهود في الاتفاقيات والمعاهدات الدولية، واعتمدت الدراسة المنهج الاستقرائي الوصفي، وتوصلت إلى نتائج منها: أن الاتفاقيات العالمية والعربية جرمت أي فعل من شأنه أن يؤثر على أداء الشهادة ويعرقل سير العدالة والتحقيق، وكثير من الاتفاقيات الدولية لم تفصل في الإجراءات المتبعة للحماية الإجرائية لاختلاف الأنظمة القانونية بين الدول الموقعة على الاتفاقية، وعدم وجود برامج حماية للشهود في جميع الدول، وعدم قدرة الدول على تكاليف القوانين ذات الصلة، وأوصت الدراسة بوضع برامج عالمية موحدة لحماية الشهود موضوعيًا وإجرائيًا، وتخصيص ميزانيات مالية لوحدات حماية الشهود وبرامجها في كافة الدول.
معاني ألفاظ الحس في القرآن الكريم "جمعا ودراسة"
Authors: العنزي شاهه الطوير معيوف
Published: September 2024

تناولت هذه الدراسة الحديث عن معاني ألفاظ الحس في القرآن الكريم - جمعا ودراسة - وبينت الدراسة أن البحث يتكون من مقدمة وتمهيد وأربعة ومباحث وخاتمة وفهرس للمصادر والمراجع فالمقدمة تشتمل من أهمية الموضوع وأسباب اختياره وأهداف البحث والدراسات السابقة، ومنهج البحث وخطته، والتمهيد اشتمل على التعريف بمفردات عنوان البحث، ثم ذكرت الدراسة أربع مباحث حول معاني الحس في القرآن الكريم المبحث الأول بعنوان: الحس بمعنى الرؤية، المبحث الثاني بعنوان: الحس بمعنى القتل، والمبحث الثالث: بعنوان الحس بمعنى البحث، المبحث الرابع بعنوان: الحس بمعنى الصوت، وطوفت الدراسة حول هذه المعاني من خلال بيان المعاني اللغوية والأعرابية، والنكات البلاغية ومناسبة الآية بما قبلها، وفقه الآية والمعنى الإجمالي وذكرت الدراسة جملة من النتائج من أهمها: من ازداد علماً بالله لا يمكن أن يدب إليه اليأس مثقال ذرة، فإذا ضعف العلم بالله تبارك وتعالى يمكن أن يصل بعض اليأس إلى القلوب.
شهادة الشهود عن طريق استخدام التقنية الحديثة
Authors: السواط ماجد خلف سالم , نور روزمان بن محمد , جمال الدين محمد حافظ
Published: September 2024

تتناول هذه الدراسة شهادة الشهود عن طريق الوسائل الإلكترونية والتقنية الحديثة، وتهدف إلى بيان مفهومها وأساسها الذي تقوم عليه، وصور أدائها، كما تبين هذه الدراسة الضوابط اللازمة في أداء الشهادة عن طريق استخدام التقنية، ومدى حجيتها، وكذا مدى التزام القاضي الجنائي بالأخذ بها في إثبات الوقائع الجنائية.
وقد اعتمدت الدراسة المنهج الوصفي التحليلي والدراسة الميدانية، حيث عمدت إلى تحليل المواثيق والمعاهدات الدولية والنظام السعودي المتعلقة بقانونية الأخذ بشهادة الشهود عن طريق الوسائل الإلكترونية والتقنية الحديثة، ثم الدراسة الميدانية وتوزيع الاستبانات في بيئة عمل متصلة بمحل البحث.
وخلصت الدراسة إلى أن الشهادة بالوسائل الحديثة وسيلة من وسائل الاثبات المعاصرة، تتمتع بقوة الشهادة بالوسائل التقليدية، وهذا يتوافق كليًا مع رؤية 2030 وما تصبو إليه من الاعتماد على كل ما هو جديد مما له أثر على تحقيق العدالة بشكل عام.
وتوصي الدراسة بإصدار نظام خاص بقواعد الإثبات في القضايا الجزائية يتضمن وضع آليات مراقبة تعزيزية بشكل إلكتروني، من خلال إنشاء وحدة خاصة من قضاة التفتيش القضائي لمراقبة القاضي الجنائي أثناء سماع شهادة الشهود، كما توصي بضرورة إصدار نظام خاص بالإثبات في المسائل الجزائية يفصل فيه أحكام الشهادة ويفرد لها فصلًا مستقلًا، وضرورة وضع ضوابط واضحة ومحددة للشهادة يمكن للقاضي أن يتكئ عليها ولا يترك دليل بحجة الشهادة لتقدير القاضي دون قواعد ومرتكزات وقيود واضحة، فإن قضاء القاضي بعلمه وتقديره للأدلة بذاته وشخصه أمر لم يعد من المقبول التوسع فيه، وهذا يؤكد ضرورة استحداث نظام خاص للإثبات الجزائي.
علاقة المستوى التعليمي والحالة الوظيفية بعوامل تأخر الزواج لدى السعوديات بمدينة الرياض
Authors: الرويلي نورة بنت مفلح
Published: September 2024

هدفت هذه الدراسة التعرف إلى علاقة المستوى التعليمي والحالة الوظيفية بعوامل تأخر الزواج لدى السعوديات بمدينة الرياض، واستخدمت الدراسة منهج المسح الاجتماعي على عينة عشوائية من السعوديات العازبات البالغات بمدينة الرياض بلغت (402) فتاة، طبقت عليهم، وتوصلت إلى أن هناك عدة عوامل اجتماعية تساهم في تأخر الزواج لدى السعوديات منها: (الرغبة في الاستقلالية، وتحقيق الذات، والمخاوف والتحديات الاجتماعية..)، كما أن هناك عدة عوامل اقتصادية منها: (السعي للاستقلالية المالية، وتحقيق مستوى معيشي أفضل، ...)، بالإضافة إلى العوامل النفسية والذاتية ومنها: (الخوف من الالتزام، والخوف من الفشل..)، ولم توجد فروق دالة إحصائيًا بين استجابات المشاركات حول العوامل الاجتماعية، وفقًا للمستوى التعليمي، بينما توجدت فروق دالة إحصائيًا في العوامل الاقتصادية والنفسية، ووجود فروق دالة إحصائيًا في استجابات المشاركات حول العوامل الاجتماعية والاقتصادية والنفسية، وفقًا للحالة الوظيفية للمشاركات، وبناء على لك قُدمت بعض من التوصيات والمقترحات.
الأحاديث الواردة في تفطير الصائم
Authors: العقيل منصور بن عبد الرحمن عقيل
Published: September 2024

يتناول هذا البحث فضائل إطعام الطعام، والأحاديث الواردة في السنة النبوية، وبيان أحوالها، والحكم عليها، ثم تناول مسألة ما يَصْدُق عليه مُسَمَّى إفطار الصائم، وبأي شيء من الطعام ينال الْمُفَطِّرُ الأجر المذكور في الحديث، ثم أوردت الأحاديث التي فيها فضل تقطير الصائم، التي وردت بالسنة النبوية، وعددها خمسة أحاديث أربعة منها مرفوعة، وواحد منها عن أبي هريرة رضي الله عنه موقوفاً، ولكن له حكم الرفع.
قمت بدراسة أسانيدها وطرقها، والحكم عليها وجميع ما وقفت عليه في طرقها كلام، وسندها ضعيف، إما بسبب ضعف أحد رواته، أو عدم الاتصال بينهم.
وبالجملة لم يثبت حديث في فضل تفطير الصائم، إلا أنه يدخل في فضل إطعام الطعام، وهو يشمل إطعام الغني والفقير، الصائم والمفطر.
الفاعلية الذاتية وعلاقتها بالسلوك الإيجابي لدى طلبة جامعة الطفيلة التقنية
Authors: الكفاوين عطاف محمد
Published: September 2024

هدفت هذه الدراسة إلى التعرف على الفاعلية الذاتية وعلاقتها بالسلوك الإيجابي لدى طلبة جامعة الطفيلة التقنية، حيث تم اختيار عينة الدراسة بالطريقة العشوائية من الطلبة المسجلين على الفصل الدراسي الثاني2024/2023، وقد بلغت العينة (662) طالباً وطالبةً، وتم استخدام مقياس للفاعلية الذاتية (محمد، 2019) حيث تكون المقياس في صورته النهائية من (17) عبارة ومقياس للسلوك الإيجابي (بربخ، 2015) حيث تكون المقياس في صورته النهائية من (45) عبارة موزعة على ثلاثة أبعاد هي: السلوك الشخصي الإيجابي والسلوك الاجتماعي الإيجابي والسلوك الأكاديمي الإيجابي. وقد أظهرت نتائج الدراسة أن مستوى الفاعلية الذاتية لأفراد عينة الدراسة كان في المستوى المتوسط وأن مستوى السلوك الإيجابي متوسطاً، وأن هناك علاقة ارتباطية موجبة ضعيفة ذات دلالة إحصائية بين الفاعلية الذاتية والسلوك الإيجابي، ولا توجد فروق دالة إحصائياً في مستوى الفاعلية الذاتية أو مستوى السلوك الإيجابي تبعا لمتغير جنس الطالب (ذكر، أنثى)، وقد أوصت الدراسة الجامعات بعمل البرامج التي من شأنها رفع مستوى الفاعلية الذاتية والسلوك الإيجابي لدى الطلبة.
موقع اللغة في أسباب اختلاف المفسرين
Authors: الخياطي محمد حزام
Published: September 2024

هذه الدراسة تهدف إلى بيان مكانة اللغة في أسباب اختلاف المفسرين باعتبارها أهم شرط من شروط التفسير؛ إذ لا سبيل إلى فهم كتاب الله إلا بمعرفة لغة العرب وطرائقها وأساليب خطابها، وبيان أثر اللغة في اختلاف المفسرين على التفسير.
وقد تناول البحث بيان مصادر التفسير، وأن اللغة من أهم مصادر التفسير بنوعيه (التفسير المأثور، والتفسير بالرأي). كما تناول البحث بيان مكانة اللغة في أسباب اختلاف المفسرين، وأن اللغة تعد أكثر أسباب الاختلاف في التفسير في القديم والحديث، وأن كتب التفسير حافلة بكثير مما وقع من الاختلاف في التفسير بين الصحابة والتابعين ومن بعدهم، ويرجع في غالبه إلى اللغة وما تحتمله من معان.
كما تناول البحث أثر اللغة في اختلاف المفسرين من خلال جملة من الأمثلة التطبيقية، وكذلك بيان أثر اللغة في توجيه القراءة وأثر ذلك في الاختلاف في التفسير، وأن توجيه القراءات هو أحد الميادين التي ولجها اللغويون لبيان القراءات واختلافها من وجوه العربية.
صور من مخالفات بعض المستمعين للقرآن الكريم وبيان حكمها
Authors: غبان خضرة بنت إبراهيم علي حامد
Published: September 2024

بيَّنت الدراسة حكم الإنصات لتلاوة القرآن الكريم، وأنه يعتريه الأحكام التكليفية الخمسة، بحسب حال السامع وقت السماع، إذ المستمعون لا يستون في الحكم، فمنهم من يكون الإنصات في حقه واجبًا كالمعني بالسماع ولو في غير الصلاة، ومنهم من يكون الاستماع في حقه سنة مؤكدة كالمنفرد بالسماع وليس عنده من ما يشغله، على الخلاف في ذلك بين الأحناف وبقية المذاهب، على خلاف بين الكراهة والتحريم، وكل هؤلاء تقع منهم مخالفات وقت استماعهم لتلاوة القرآن، ولأجل بيانها والتنبيه عليها سيق هذه الدراسة، حيث تناولت الحديث عن سبع صور لهذه المخالفات؛ للتحذير من الوقوع فيها، باعتبار أن سماع التلاوة القرآنية عبادة كغيرها من العبادات لها أحكام وآداب يجب على السامع أن يراعيها عند استماعه، ليحصل له المقصود من السماع بصلاح القلب وثبوت الأجر.
الموضة وأحكامها بين المشروع والممنوع
Authors: باعلوي حاشد عبده صالح , القطمي مبارك علي أحمد
Published: September 2024

هدف هذا البحث إلى معرفة الموضة وأحكامها في الفقه الإسلامي، المشروعة والممنوعة، وقد اشتمل البحث على مقدمة وثلاثة مباحث وخاتمة، أما المبحث الأول، فقد تناول التعريف بالموضة وأنواعها، وأما الثاني: فقد تناول أحكام الموضة بين المشروع والممنوع، وأما الثالث، فقد تكلم عن ضوابط الموضة وتأثيرها على القيم والأخلاق، واستخدم الباحث: المنهج الوصفي التحليلي الاستنباطي، وكان من أهم نتائجه: أن الموضة ذو شقين مشروع وممنوع، فالمشروع، كجمال المظهر وأناقته، واللباس ونظافته، وتزين المرأة لمثيلاتها وزوجها وعكسه، وتهذيب الرجل لشعره، والممنوع، كشفافة الثياب وضيقه، والإسراف ومخيلته، وتشبه الرجال بالنساء وعكسه؛ وأن الباحثين يوصيان: المتخصصين في الشريعة الإسلامية بمزيد من البحوث في الموضة، وتثقيف أفراد المجتمع بأحكامها، وزرع الثقة لديهم بثقافتنا وأعرافنا وديننا.
Radioterapia intraoperatoria con electrones en el tratamiento conservador del cáncer de mama. Experiencia del Departamento de Oncología Radioterápica del Hospital Clínica Bíblica.
Authors: Argüello-Méndez Julio , Loría-Ruiz Rolando
Published: September 2024

Objetivo: Describir la experiencia de la RIO en el Hospital Clínica Bíblica, San José, Costa Rica. Materiales y Métodos: De mayo de 2012 a septiembre de 2014, se ha tratado a 57 pacientes en el Hospital Clínica Bíblica; con haz de electrones con radioterapia intraoperatoria después del tratamiento quirúrgico conservador para el cáncer de mama temprano o avanzado, con refuerzo o como un único tratamiento de radioterapia. Resultados: La duración promedio de entrega de los tratamientos es de 69,4 segundos (rango: 30s a 128s). Conclusiones: Un haz de electrones de radioterapia intraoperatoria en el tratamiento conservador del cáncer de mama podría ser considerado una opción adecuada para pacientes de bajo riesgo y algunos pacientes con riesgo intermedio bien seleccionados, o para disminuir el tiempo total del tratamiento en los casos de cáncer de mama tempranos, o como un refuerzo anticipado en estadios avanzados.
Abordaje de la migraña en atención primaria
Authors: Lobo D. Alejandra , Vindas Cruz Adriana
Published: September 2024

Resumen Al ser la migraña una patología de la consulta diaria, el médico general se ve en el deber de conocerla a profundidad, ya que aunque presenta síntomas muy característicos que permiten realizar un buen diagnóstico diferencial, las variables de presentación son diversas, y suele existir resistencia al tratamiento en algunas de ellas. Por otro lado, se convierte en algo vital la detección oportuna de esta patología para un manejo inmediato que permita ayudar al paciente a disminuir la carga emocional, familiar y la afectación laboral que muchas veces representa este padecimiento. A pesar de reconocer este hecho, los avances en sí sobre la migraña son pocos, y muchas veces se suele dejar a criterio del médico de atención primaria el diseño individual del manejo, por lo que es importante conocer sus manifestaciones clínicas, las actualizaciones, en cuanto a teorías sobre su fisiopatología y tratamiento tanto farmacológico como complementario. A lo largo de esta revisión se discute cada uno de estos puntos antes mencionados. Se concluye que, a pesar de los avances terapéuticos que existen actualmente, se desconoce la fisiopatología exacta que pueda llevar a un tratamiento más al punto, razón por la que es fundamental apoyar e insistir en el inicio de nuevas investigaciones.
Legal responsibility for negative effects of the vaccine: Nature and financial compensation
Authors: Alazzam Farouq Ahmad Faleh , Al-zoubi Tariq Muhammad Hussein , Aldghaim Rafat A′yesh Issa , Al-Maagbeh Mohmmed Mufadi , Bani-Meqdad Mohammad Ali Mohammad , Shakhatreh Hisham Jadallah Mansour
Published: September 2024

The purpose of the article is to form an optimal scenario for receiving financial compensation for the negative consequences of vaccination. The object of the study is responsibility for unsuccessful vaccination. The scientific task is to form an approach to assessing possible scenarios for receiving adequate financial compensation. For this purpose, a methodology is presented that includes a scenario approach for applying the cognitive analysis method. As a result, the article presents a toolkit for studying the influence of factors of negative effects of vaccination through the definition of key legal and financial factors, their mutual influence, which was measured using correlation and regression analysis, and possible options and directions for choosing the optimal scenario for receiving financial compensation. The study has a limitation and does not take into account all possible factors, factors and negative effects. Prospects for further research should be aimed at a thorough analysis of the socio-demographic consequences of unsuccessful vaccination.
Bus rapid transport system for urban mobility in Ahmedabad: A people’s perception of service quality and performance of BRTS
Authors: Minampat Venkat Ram Reddy , Divi Sriram , Raghuvanshi Jyothi Singh
Published: September 2024

Around the world, bus rapid transit systems are gaining popularity as they are a low investment option compared to rail transport but have facilities that cater to rail transport Numerous Indian cities have chosen the concept under the Jawaharlal Nehru National Urban Renewal Mission Scheme. A quality and secure transportation system was one of the mission's key goals, therefore bus rapid transit systems were promoted. Everyone wants their commute to be a little faster, in fact wherever we are going is more comfortably than before. Jan Marg Bus Rapid Transit, India's first top-notch bus rapid system, was introduced in 2009 in Ahmedabad. The Jan Marg system set a benchmark for the country and had an impact upon systems all over India, including recently introduced Rainbow rapid-transit bus system in the twin cities of Pune and Pimpri-Chinchwad. Since May 2013, the Ahmedabad Bus Rapid Transit System has been successfully carrying bus passengers over a designated rapid corridor. With the introduction of Intelligent Transport Management Systems (ITMS), BRTS Transport services become more inclusive in nature. Services delivery became more efficient and qualitative in nature. This study's aim is to examine the performance of the system based on how users feel about BRTS integrated with ITMS under the improved services they have received under and where there may be even more room for improvement. A questionnaire was made, and passengers' perspectives were collected and evaluated. The majority of the inquiries revealed that the passengers were satisfied and largely approved of the system. The performance of the system will be enhanced if certain issues are properly addressed and fixed.
The personal jurisdiction of the Arab court for human rights compared to the European court of human rights
Authors: Al-Dabbas Ali Muhammad , Al-Momani Sayel Mufleh , Helo Shady Helo Abu , Qaisi Abeer Al , Abuelzeet Rehan , Al-Andali Mohammad Moqbel
Published: September 2024

The research dealt with the personal jurisdiction of the Arab Court for Human Rights compared to the European Court of Human Rights, by indicating who are the natural persons and legal persons who are entitled to file claims and the conditions for their acceptance with the two courts, adopting the analytical approach and the comparative approach to find out the deficiencies in the statute of the Arab Court for Human Rights and address them. Several results and proposals were reached. As for the most important results, they are represented by the narrowing of the scope of personal jurisdiction in the statute of the Arab Court for Human Rights and confining it mainly to the states parties to the Arab Charter for Human Rights, and on the condition that there is a personal interest for the state in the case, while the scope of personal jurisdiction in the European Court of Human Rights has expanded to include the states parties to The European Convention on Human Rights without the existence of a personal interest and any individual, non-governmental organization or group of persons, and that the jurisdiction of the Arab Court of Human Rights is optional, while we find it compulsory at the European Court of Human Rights. As for the most important proposals, it is represented by amending the text of Article (19) of the statute of the Arab Court for Human Rights, to expand the scope of personal jurisdiction, by defining the right of individuals, non-governmental organizations, and a group of persons to file lawsuits in response to the development of the individual’s status in international law. Also, amending the statute of the Arab Court for Human Rights, by adding a provision that makes the court's jurisdiction compulsory in all cases.
Towards economic stability: Analysis of Msme business sustainability in central Java province post the COVID-19 pandemic
Authors: Aziz Fathul Aminudin , Utami Hastin Tri , Wanojaleni Kartika , Edy Slamet Cahyo
Published: September 2024

The primary objective of this study is to determine, via empirical testing, which internal and external factors have the greatest impact on micro, small, and medium-sized enterprises (MSMEs). (b) Conduct an empirical study to determine are affected by external factors that influence their sustainability. c) Find out how much MSMEs really use information and digital technologies by conducting an empirical test. (d) To see how well businesses were able to keep running following the COVID-19 pandemic. The crux of the matter is to understand how the pandemic has affected MSMEs from the inside and out, including how income has dropped, how consumer behavior has changed, and how supply chains have changed, acknowledging the merits and demerits, adjusting business models to account for human resources availability, fostering collaboration and partnerships, enabling digital empowerment, regulating policies, and providing education and training. The analysis's findings can inform policy suggestions and strategy formulation to help micro, small, and MSMEs in Central Java Province weather the post-COVID-19 economic storm.
Ambidextrous leadership, customer orientation, environmental innovation to improve service innovation capability through digital capabilities and technological capabilities as mediating variables in Umkm in Berau District, East Kalimantan
Authors: Hasnawati  , Kusumaningtyas Amiartuti , Cempena Ida Bagus
Published: September 2024

Berau District is in the northern part of East Kalimantan Province and borders directly with North Kalimantan Province. As of 2014, the administrative territory of Berau District was divided into 13 districts with a total of 100 villages and 10 villages. Micro, Small and Medium Enterprises (MSMEs) are economic drivers in Berau district that are still faced with classical problems such as infrastructure, licensing, marketing, distribution and financing as well as post- 19 recovery processes. In connection with the problem, to build micro, small enterprises, and corporations, it is necessary to support the healthy real sector to combat poverty through the strengthening of the purchasing power of better society and the help of financing with light interest. The purpose of this research. Based on the background and the formula of the problems that have been outlined earlier, then the purpose of this research is to develop a model of the conceptual framework by means of proof and analysis; (1). The impact of ambidextrous leadership on digital capabilities on MSME perpetrators in Berau district (2), the impact of customer orientation on digital capacity on MSE perpetrator in Beru district (3), the effect of environmental innovation on digital Capabilities in MSE Perpetrator in Berau district (4). The effect of digital capability on technological capacities in the UMKM Perpetrant in Berea district (5), the influence of digital capacities on service innovation capability in UMM Perpetrator at Beraus district (6). The total sample that meets the criteria in this study is 353 samples and is processed using SmartPLS data processing. The results of this study indicate that there is a direct relationship between the impact of Ambidextrous Leadership, Customer Orientation, Environmental Innovation on Service Innovation Capability.
Knowledge and attitudes about interactive digital tools for learning medical terminology among students
Authors: Banafi Norah , Kaliyaperumal Raji
Published: September 2024

Learning is a self-contained process, and the most active components are the learners' imaginative thinking and constructive cognitive engagement. It's been established time and time again that effective interactions and communication between professors and students are crucial to learning. This essay aims to demonstrate the usefulness of interactive technology. This study used a descriptive study approach. Convenience sampling was used to pick 136 students from the College of Applied Medical Sciences at King Khalid University (KKU), Saudi Arabia, who enrolled in a 4-year Baccalaureate nursing program. This research was conducted in the 2021–2022 academic year. A questionnaire, such as the five-point Likert scale, was used to collect the data. SPSS was used to do statistical analysis on the collected replies. The findings showed that employing an interactive digital tool significantly improved the students' understanding, and they also showed a good attitude regarding using the session to learn about medical terms.
COVID-19 pandemic and environmental protection: Imperatives for environmental law and management in Nigeria
Authors: Ekpoudo Anthony , Ebu Alex Abang , Aniashie Akpanke Shishiitileugiang , Edet Okpong Denis , Eteng Ekpe Wekeekayo
Published: September 2024

Across the global community, many countries have been ravaged by the challenge of the COVID-19 pandemic. Nigeria is no exception. Since the country recorded its first index case in February 2020, the number of cases and fatalities has been on the increase. Although the authorities in Nigeria have endeavoured to adopt some meaningful response to the pandemic, with a fragile healthcare system, the pressure posed by this issue is enormous and the matter has persisted. COVID-19 is certainly a zoonotic or environmentally related scourge. In this work, the environmental aspect of the pandemic has been traced and their consequences highlighted. The study also considers the responses to the problem and from the environmental law perspective examines the regulations concerning these kinds of diseases. It is opined that the effective management of the environment by adherence to agreements, laws, and policies, investment in environmental restoration and new technologies, and general reorientation of citizens towards the exploitation and use of environmental resources are better approaches to checking the emergence of this kind of problem in future and generally sustaining a green environment.
Epistemic injustice of the digital divide
Authors: Khort Mikhail , Karimov Artur , Murtazin Salavat , Khayaleeva Adelya
Published: September 2024

This article examines the problem of the digital divide through the lens of social epistemology, focusing on such aspects as the knowledge gap and epistemic injustice. The authors uses the method of comparative analysis and conceptual analysis to explore the epistemic characteristics of the digital divide and proposes new approaches to overcoming it. The article emphasizes the importance of achieving the UN Sustainable Development Goals related to education and access to knowledge in the hyperinformation age. The originality of the study is that the phenomenon of the digital divide is seen as a knowledge gap. The authors illustrate the digital divide with the example of the problem of equitable access to AI in education and medicine. As a result, the study is not only theoretically significant but also has social implications, stressing the need to bridge the digital divide as a condition for equitable access to information and knowledge for all segments of society.
Managing digital finance: The role of cryptocurrency in financial reporting
Authors: Yusuf Muh. Fathir Maulid , Rauf Dian Mayafaty , Hamid Ahmad , Sultraeni Wiwin , Garusu Ilham Akbar
Published: September 2024

This study aims to explore the role of cryptocurrency in corporate financial reporting amidst the rise of digital finance. The research adopts a descriptive-analytical design, utilizing both qualitative and quantitative methods. Data were collected from literature reviews, interviews with financial practitioners, and case studies of companies integrating cryptocurrencies into their financial operations. The findings highlight that while cryptocurrencies offer opportunities for portfolio diversification and faster cross-border transactions, they also introduce challenges, such as price volatility and regulatory uncertainty, which complicate asset valuation and risk management in financial statements. The study reveals that companies like Tesla and MicroStrategy have reported increased asset values due to cryptocurrency investments, but also faced difficulties in providing consistent financial estimates due to market fluctuations. The research concludes that clear regulatory frameworks and enhanced accounting standards are essential for transparent and reliable financial reporting. Practical implications include the need for financial practitioners to develop expertise in cryptocurrency valuation and risk management while ensuring compliance with international financial reporting standards.