bluuebunny/crossref_metadata_2025 huggingface dataset:
Sustainability of the Currency Board in Bosnia and Herzegovina in the Conditions of a Negative Interest Rate on the Reserve Currency
Authors: Tomaš Rajko
Published: January 2023

The Currency Board in Bosnia and Herzegovina (BiH) uses the euro as a reserve currency in the conditions of a negative nominal interest rate on deposits with the ECB. In this paper, we investigated the impact of negative interest rates on deposits and negative yields on bonds denominated in euro on the general advantages of the currency board and the consequences for the functioning of the currency board in BiH. The impact of negative interest rates was measured by the currency board coverage index (IC). A negative nominal interest rate on the reserve currency creates a negative seigniorage in the country of the currency board, increases the costs of issuing domestic money and reduces the competitiveness of the economy. The monetary policy of the ECB in the conditions of the COVID-19 crisis generates negative influences on the functioning of the currency board. The COVID-19 crisis poses a threat to currency board coverage in BiH. Technically, a currency board can also function in terms of negative interest on the invested reserve currency as long as it can cover the costs of its business.
The Art and Science of Consultations in Bovine Medicine: Use of Modified Calgary – Cambridge Guides, Part 2
Authors: Carr Amanda Nicole , Kirkwood Roy Neville , Petrovski Kiro R.
Published: January 2023

This article, part 2 of a 2-part series, describes the next two steps in the application of the Modified Calgary-Cambridge Guides (MCCG) to consultations in bovine medicine, ‘explanation and planning’, and ‘closing the consultation’, and introduces concepts that are associated with all the components of the guide, ‘building the relationship with the client’ and ‘providing structure to the consultation’. Part 1 introduced the aim and framework of the MCCG which enables the practitioner to gain an insight into the client’s understanding of the problem, including understanding aetiology, epidemiology and pathophysiology. Part 2 introduces the framework that provides the opportunity to understand the client’s expectations regarding the outcome, their motivation and willingness to adhere to recommendations. It also describes how to engage and acknowledge the client as an important part of the decision-making process, how to establish responsibilities of both the client and practitioner, and how to reach out to the client at the conclusion of the consultation to make certain that the client’s expectations were met.
CONCEPT as a Travelling Concept in Subject-Matter Teaching and Learning
Authors: Bohlmann Markus
Published: January 2023

Research on students´ concepts based on conceptual change theory is being conducted in relation to more and more different subject content. CONCEPT, the concept of a concept, however, has very different meanings and functions in different contexts of subject-matter teaching and learning. In this study tools of analytic philosophy of science and philosophy of cognition are applied to examine the recent process of a research transfer from science education to philosophy education. Transmutations of CONCEPT are evident in empirical studies in philosophy education. However, such a transfer process can reveal problems of CONCEPT that affect any subject- matter research on student´s concepts. Three main problems are shown: a problem that is new to philosophy education, one that is a legacy of science education, and another, future problem that is emerging with conceptual engineering. The solution to these problems could lie in an integrated interdisciplinary project, the theoretical determination of subject-matter CONCEPT.
Apolipoprotein E polymorphism in a Romanian population
Authors: Diaconu Rodica , Dumitrașcu Andreea-Ramona , Liehn Elisa , Pîrvu Andrei , Ioana Mihai , Alexandru Dragoș , Țieranu Eugen , Bălșeanu Tudor-Adrian , Donoiu Ionuț
Published: January 2023

Background: Apolipoprotein E (ApoE) is a ubiquitous protein involved in maintaining cholesterol homeostasis and lipoprotein clearance from circulation. It is coded by three alleles (ε2, ε3, ε4) with six genotypes (ε3/ε3, ε3/ε4, ε2/ε3, ε4/ε4, ε2/ε4, and ε2/ε2). Several studies have shown a relationship between ApoE-specific isoforms and different diseases. There are few data about the prevalence of ApoE polymorphism in the Romanian population. We aimed to assess the prevalence of Apolipoprotein E alleles in a healthy population from Romania and compare it with the data found in other countries of Europe.

Methods: ApoE genotype was examined in 187 unrelated healthy volunteers (131 males and 56 females) from the region of southwest Romania (mean age 48.04 ± 8.35 years). Analysis of ApoE genotype variants was done using the PCR method with allele-specific oligonucleotide primers.

Results: The frequency of heterozygote genotypes ε2/ε3, ε2/ε4, and ε3/ε4 was 4.8%, 1.6%, and 24.73%, respectively, while the frequency of homozygote genotypes ε2/ε2, ε3/ε3, ε4/ε4 was 0.5%, 66.12%, and 2.1%, respectively, with a mean frequency of ε2, ε3 and ε4 alleles of 6.9%, 96.25%, and 28.49%, respectively. East European countries have the lowest mean frequency of the ε4 allele (9.96%), and the highest frequency of the ε4 allele (23.38%) is in the Nordic Countries.

Conclusions: The ε4 allele prevalence in this Romanian population is higher in comparison with other European countries, similar to Nordic countries of Europe.
Serum homocysteine level and severity of coronavirus disease-2019 (COVID-19)
Authors: Siregar Jelita , Darmadi Darmadi
Published: January 2023

Introduction

Coronavirus disease-2019 (COVID-19) is still a global health problem nowadays. A particular COVID-19 patients develop severe symptoms. Some biomarkers can be used to determine disease severity and improve outcome. Homocysteine is one of the novel biomarkers. The objective of this study is to determine the role of serum homocysteine level in stratifying severity of COVID-19.

Methods

A cross-sectional study was conducted in Medan, Indonesia from May to December 2021. Subjects were obtained using consecutive sampling method. Inclusion criteria was COVID-19 patients aged 18 years or older and willing to participate in the study. Patients with malignancy, chronic kidney disease, thyroid disease, coronary heart disease, and who consume several medications including cholestyramine, metformin, methotrexate, fibrate, and contraceptive pill, were excluded. Data regarding demographic, laboratory, and biomarker were gathered from each subject. Statistical analyses were conducted at 95% confidence interval.

Results

A total of 100 patients were enrolled. Most subjects were males (59%) and from Batak ethnicity (64%). Twenty percent subjects had severe COVID-19. The levels of serum high-sensitivity C-reactive protein (hs-CRP), D dimer, homocysteine, and procalcitonin were significantly higher in severe COVID-19 subjects. D dimer had the highest sensitivity (91.7%) and specificity (94.7%) in stratifying severe COVID-19, followed by hs-CRP (91.7% and 85.5%, respectively), homocysteine (87.5% and 78.9%, respectively), and procalcitonin (58.3% and 74.0%, respectively).

Conclusion

Homocysteine can be used as a biomarker to determine COVID-19 severity.
Freedom of Communication in Science in the Context of the Development of Modern Information and Communication Technologies
Authors: Adamus-Kowalska Justyna
Published: January 2023

The article presents the idea of freedom of communication and science in the context of con-temporary trends related to the development of modern information and communication technolo-gies. The research was carried out by means of literature analysis, observation, desk research, andstatistical surveys, including estimated data on changes, for example in the labour market. Refer-ence was made to the paradigm shift in the use of information and communication technologiesas a result of the pandemic. Attention was also paid to the influence of technology on the sphere ofscientific and public information. As a result of the research, changes related to the use of artificialintelligence have been noted, including threats related to the impact of technology on humans andthe environment. Another problem is the lack of knowledge about these threats and the uncriticaladoption of new technological innovations. Automated decision-making systems do not follow clearrules on accountability for the possible effects of adverse reactions. On the other hand, the develop-ment of technology is causing a revolution in the field of open access to scientific data, free of chargeand without legal and technological barriers
Use of Software Solutions for Simulations of Traffic Processes Depending on the Type of Traffic Models
Authors: Volner Ľubomír
Published: January 2023

This article is aimed at introducing the issue of simulating traffic processes and the possibility of creating traffic models using software solutions. The introduction describes the basic problems that are present for the responsible authority in the decision-making process on the implementation of transport infrastructure projects and the verification of the validity of their implementation. The importance of computer technology in the process of evaluating projects and the socioeconomic effects they bring is also mentioned. The benefits of retrospective evaluation of already implemented projects and comparison with predictions made in the preparation process in relation to the verification of forecasts and the structure and scope of input data are also indicated. In the next part, the starting points for the creation of traffic models, input data and expected outputs are summarized due to the nature of the performed simulation. The final part provides an overview of the possibilities of using software solutions for the creation of traffic models and the suitability of their application according to the specifics of the simulation and output requirements.
Strategy Development in the Service of Railway Undertakings
Authors: Nedeliaková Eva , Valla Michal
Published: January 2023

Railway undertakings face many challenges and obstacles to competition in the transport market. Strategic management methods in relation to quality assurance of services provided by carriers, used not only in transport sectors but also in industrial sectors, are a way to continuously improve the quality of services and thus the competitiveness of railway undertakings. Nowadays, customers are becoming more and more demanding, also in view of the wider range of services offered by other modes of transport. For this reason, quality requirements are increasing. Most business strategy evaluation systems are only partial, limiting themselves to the assessment of certain factors where many shortcomings remain hidden. In the same way, a strategic plan for the economic growth and development of a transport organisation does not always ensure the achievement of the set objectives.
Functions of Documentonyms-Abbreviations in the German Language of Economics and Management
Authors: Kukina N. V.
Published: January 2023

The article deals with the functions of documentonyms-abbreviations often used in the German language of economics and management. As a component of the peripheral onomastic zone, documentonyms- abbreviations form their own onomastic field and perform a number of important functions. Among them are the functions common to onyms in general, such as the address function and the function of an ethno-linguistic sign. Documentonyms-abbreviations indirectly perform a social function, because they indicate that these documents are aimed at meeting the needs of society in general and individual members of society in particular. Among the functions abbreviations perform in general is the function of compression, individualization and concretization, which is connected with the use of truncations, syllables and full words in the abbreviation, making it more recognizable; the pragmatic function and/ or the function of facilitating communication by replacing the original full prototype; dictionary enrichment function realizing their derivational potential, and the text-linking function. The specific functions of documentonyms-abbreviations are singled out. They include the function of identifying its correlation with certain management macrofields; the function of a marker that refers a document to one of the types of administrative documents; the function of an onomasiological feature or basis, depending on the position of the abbreviation in the composite created with the abbreviation-documentonym or on the position of the component in the abbreviation; the function of the top of lexical word-formation nests. The specifics of abbreviations-documentonyms are in the lack of the function of stylistic reduction, and the advertising function characteristic of other types of onyms, pragmatonyms and ergonyms, for example.
Radicals with Diplomatic Semantics in Ancient Chinese Dictionary “Shuo Wen Jie Zi”: Verification of Etymology
Authors: Khamaeva E. A.
Published: January 2023

There are several signs with «diplomatic» semantics among the 540 most ancient radicals of the Chinese writing, presented in the dictionary “Shuo wen jie zi” (1st century AD, Han era). Before the dictionary was created, Chinese writing had already existed for several thousand years; therefore some researchers (Zou Xiaoli, 2007; Oshanin, 1943) consider that the etymologies of the radicals in “Shuo wen” were formulated under the influence of the later eras and are often erroneous. The attempts are made to verify the etymologies of these signs with “diplomatic” semantics by comparing them with the more ancient forms jiaguwen and jinwen, discovered and scientifically described only in the 20th century. Such a comparison and interpretation will reveal the probable correct etymologies of the analyzed radicals of the Chinese dictionary “Shuo wen” and verify them. In addition, the study will shed light on the beginning of diplomacy in ancient China. The article also touches upon the problem of etymological analysis in a language with an ideographic type of writing, which is carried out not at the level of morphology, as in European languages, but at the level of hieroglyphic sign graphics.The problem of semantics and etymology of radicals was considered mainly by Chinese scientists (Zou Xiaoli, 2007; Wang Fengyang, 2011, etc.), while in the European linguistics, the problem was studied only fragmentarily (Kondrashevsky, 1982; Karasyova, 2019; Dictionary of etymologies, 2019). The radicals “with diplomatic” semantics, analyzed in the article, did not become the object of special study.The purpose of the article is to verify the etymology of a number of radicals in the ancient Chinese dictionary “Shuo wen jie zi” with “diplomatic” semantics, to consider the information about the dictionary “Shuo wen jie zi”, its basic radicals and their semantics, to briefly describe the features of etymological analysis in general and in Chinese language in particular, to compare the definitions of these radicals in various etymological dictionaries, thus verifying the etymologies presented in the dictionary “Shuo wen jie zi”.
Perbedaan pengetahuan gizi berdasarkan perilaku pencegahan obesitas pada pekerja muda
Authors: Stanza Aga , Karjadidjaja Idawati
Published: January 2023

Obesitas merupakan salah satu penyakit yang sering disepelekan oleh masyarakat dapat menjadi faktor risiko dari penyakit lain yang lebih berbahaya. Pengetahuan gizi kaum pekerja muda dengan umur 25 sampai 40 tahun, diharapkan dapat diterapkan dalam perilaku sehari-hari untuk mencegah obesitas. Penelitian ini bertujuan untuk mengetahui hubungan antara pengetahuan gizi dengan perilaku pencegahan obesitas pada pekerja berusia 25-40 tahun. Penelitian ini merupakan penelitian observasional analitik dengan metode potong lintang menggunakan kuesioner melalui google form dan dianalisa menggunakan t-test independen. Sampel penelitian sebanyak 132 responden adalah pekerja berusia 25-40 tahun. Didapat 18 orang (13,6%) dengan pengetahuan kurang, 91 orang (68,9%) dengan pengetahuan cukup dan 23 orang (17,42) dengan pengetahuan baik. Terdapat 19 orang (14,39%) responden dengan nilai perilaku baik, dan 113 orang (85,6) dengan perilaku kurang baik. Penelitian menunjukkan bahwa responden dengan perilaku yang baik memiliki rata-rata pengetahuan lebih tinggi 4,762 poin daripada responden dengan perilaku kurang baik. Pada penelitian disimpulkan tidak terdapat adanya hubungan antara pengetahuan gizi dengan perilaku pencegahan obesitas, (p-value 0,107). Tidak ditemukan adanya hubungan yang bermakna antara pengetahuan gizi dengan perilaku pencegahan obesitas (p-value = 0.107)
Indeks prestasi akademik ditinjau dari jalur penerimaan mahasiswa baru, status dan akreditasi sekolah sebelumnya
Authors: Chintya Michelle , Irawaty Enny
Published: January 2023

Fakultas kedokteran berkewajiban untuk memastikan mahasiswa yang diterima berpotensi sukses dalam menyelesaikan pendidikan kedokterannya sehingga proses dan kriteria seleksi masuk menjadi krusial. Salah satu kriteria seleksi mahasiswa dapat dilihat dari prestasi belajar di Sekolah Menengah Atas (SMA). Status sekolah negeri atau swasta dan peringkatnya yang ditentukan oleh Badan Akreditasi Nasional Sekolah/Madrasah (BANS/M) memengaruhi proses belajar yang akhirnya berdampak pada prestasi belajar di SMA. Jalur penerimaan seleksi masuk juga dapat menjadi faktor yang menentukan kesuksesan mahasiswa dalam pendidikannya. Studi ini dilakukan untuk mencari hubungan antara status dan akreditasi sekolah serta jalur penerimaan mahasiswa baru dengan capaian mahasiswa kedokteran yang dilihat dari indeks prestasi. Study bersifat analitik potong lintang terhadap 106 mahasiswa Fakultas Kedokteran Universitas Tarumanagara angkatan 2020 dengan mengisi kuesioner. Hasil studi didapatkan 58 (54,7%) responden berasal dari SMA swasta dan 48 (45,3%) responden dari SMA negeri. Responden yang berasal dari SMA berakreditasi A didapatkan sebanyak 102 (96,2%) responden, SMA berakreditasi B sebanyak 2 (1,9%) responden, serta SMA berakreditasi C dan tidak terakreditasi masing-masing sebanyak 1 (0,9%) responden. Responden yang diterima melalui Jalur Penelusuran Prestasi (JPP) sebanyak 68 (64,2%) responden dan yang diterima melalui Ujian Saringan Masuk (USM) sebanyak 38 (35,8%) responden. Rerata indeks prestasi responden sebesar 3,21 (0,48). Hasil analisis menunjukkan status dan akreditasi sekolah serta jalur penerimaan mahasiswa tidak memiliki hubungan yang bermakna dengan indeks prestasi (p value > 0,05). Indeks prestasi akademik pada studi ini mungkin dipengaruhi oleh banyak faktor lain. Meskipun demikian, seleksi masuk fakultas kedokteran tetap harus dilakukan dengan proses dan kriteria yang ketat.
Sindrom kompartemen pada fraktur antebrachii: Studi kasus
Authors: Sardjono Michelle , Dhani Dhevariza Pra
Published: January 2023

Sindrom kompartemen merupakan kasus yang paling banyak ditemui pada populasi pediatrik dengan insiden tertinggi terjadi pada rentang usia 10 hingga 14 tahun. Hal ini dikarenakan rasio massa otot terhadap ukuran kompartemen relatif lebih tinggi dan struktur fasia yang lebih kuat mengurangi kemampuan kompartemen untuk mengakomodasi peningkatan pembengkakan yang signifikan. Kegagalan untuk menangani sindrom kompartmen dengan cara yang cepat dapat menyebabkan cacat permanen (kontraktur otot) pada anggota tubuh yang terkena. Studi ini memaparkan sindrom kompartemen setelah fraktur antebrachii pada seorang anak laki-laki usia 8 tahun. Pasien datang dengan keluhan nyeri pada lengan kiri sehingga sulit digerakkan. Pasien mengatakan terjatuh dari pagar 2 hari sebelum masuk rumah sakit dan sempat dibawa ke tukang urut. Lengan dan tangan kiri bertambah bengkak disertai lenting-lenting kecil berisi air. Pasien datang dalam kondisi diperban dengan lilitan kencang. Pasien diduga mengalami sindrom kompartemen. Pemeriksaan fisik: pasien tampak sakit sedang, kesadaran compos mentis (E4V5M6), tekanan darah 100/80 mmHg, frekunsi napas 20 x/menit, denyut nadi 71 x/menit, suhu tubuh 36,50 C. Pada regio dorsum manus et antebrachii sinistra didapatkan jejas, edema, bula, mengkilap, pallor, hangat, pain, pressure, parasthesia, pulselessness, paralysis. Pemeriksaan CT-scan didapatkan fraktur 1/3 proximal os radius sinistra dengan displace fracture, fraktur 1/3 tengah os ulna sinistra dengan displace fracture, dan soft tissue swelling daerah lesi. Pasien diberikan terapi farmakologi berupa Ringer Lactate 500 cc per 24 jam, cefotaxime 2 x 1 gram, dan paracetamol 3 x 500 mg serta terapi non-farmakologi berupa debridemen dan pemasangan spalk di bagian bawah sebagai alas.
Pengetahuan, sikap dan perilaku pelajar SMAN 4 Sukabumi terkait pencegahan penyakit akibat Tinea versikolor
Authors: Atzmardina Zita , Sunardi Cindy Paramitha
Published: January 2023

Tinea versikolor atau yang lazim dikenal dengan penyakit panu merupakan penyakit yang diakibatkan oleh infeksi jamur. Infeksi jamur merupakan penyebab utama ke empat dari penyakit kulit di seluruh dunia. Pengetahuan yang baik mengenai kebersihan diri diperlukan untuk mengurangi terjadinya Tinea versikolor. Studi ini bertujuan untuk mengetahui tingkat pengetahuan, sikap dan perilaku pelajar di SMAN 4 Sukabumi. Metode yang digunakan ialah analitik observasional dengan desain cross sectional. Alat ukur yang digunakan dengan menggunakan kuesioner yang sudah divalidasi. Uji statistik menggunakan uji Fisher exact. Hasil yang didapatkan pada 194 responden menunjukkan ada hubungan bermakna (P<0,05) antara pengetahuan, sikap dan perilaku responden. Tingkat pengetahuan dan sikap terhadap perilaku pencegahan Tinea versikolor masing-masing menunjukkan p-value 0,002 dan 0,008 secara berurutan; hubungan tingkat pengetahuan terhadap sikap pencegahan Tinea versikolor menunjukan p-value 0,001.Tingkat pengetahuan, sikap, dan perilaku responden juga tergolong baik (90,7%; 86,1%; 96.4%). Hasil studi ini dapat disimpulkan adanya hubungan yang bermakna antara tingkat pengetahuan, sikap dan perilaku pencegahan Tinea versikolor pada pelajar di SMAN 4 Kota Sukabumi.
Chiles en México: Historias, culturas y ambientes
Authors: Vásquez Dávila Marco Antonio , Aguilar Meléndez Araceli , Katz Esther , Manzanero Medina Gladys Isabel
Published: January 2023

Un grupo de investigadores de la Universidad Veracruzana, del Instituto Tecnológico del Valle de Oaxaca, del CIIDIR Oaxaca del Instituto Politécnico Nacional y del Instituto de Investigación para el Desarrollo, de Francia, se ha dado a la tarea de conjuntar los estudios culturales que sobre el chile se han desarrollado en México. En un esfuerzo interdisciplinario, reúnen textos que abordan la temática de este fruto desde muy diversas perspectivas: an­tropológica, gastronómica, histórica, biológica, medicinal. Su labor ha rendido más de un resultado: la primera compilación (Los chiles que le dan sabor al mundo) fue publicada en 2018. En alcance de esta, el segundo volumen amplía y profundiza los saberes alrededor de los chiles, del mito a la genética, des­de la dispersión de las semillas hasta los usos culinarios en recetas milenarias, en la cocina familiar o en restaurantes, y los usos alimenticios, curativos y rituales en espacios rurales así como urbanos. Queda así en evidencia la importancia del picante como marcador de identidad local latinoamericana: "dime qué chile consumes y te diré de dónde eres" Y es que, como todos lo sabemos, en los hogares mexicanos no puede faltar una salsa, ya sea de serrano, piquín, habanero o de jalapeño. De esta manera, en Chiles en México. Historias, culturas y ambientes se da continuidad y se enriquece nuestro aprecio por los sabores de México, por su riqueza gastronómica y la herencia cultural de generaciones. Que este rescate siembre en el lector la necesidad de valorar y de preservar lo que este sabroso ingrediente representa.
Hubungan Status Gizi dengan Kejadian Hiperemesis Gravidarum
Authors: Fadhilah Alfin Rahma , Sulastri Delmi , Karmia Hudila Rifa
Published: January 2023

Latar Belakang: Hiperemesis gravidarum adalah mual dan muntah berlebihan yang terjadi pada ibu hamil muda, yang dapat memengaruhi keadaan umum dan mengganggu aktivitas sehari-hari. Penyebab terjadinya hiperemesis gravidarum belum diketahui secara pasti, namun status gizi merupakan salah satu faktor risiko yang dapat dimodifikasi dan sering dihubungkan dengan kejadian hiperemesis gravidarum.
Objektif: Mengetahui hubungan status gizi dengan kejadian hiperemesis gravidarum.
Metode: Penelitian ini merupakan penelitian analitik retrospektif dengan pendekatan case-control. Sampel pada penelitian ini terdiri atas 23 sampel kasus dan 23 sampel kontrol dengan teknik pengambilan sampel kasus yaitu secara total sampling dan sampel kontrol secara systematic random sampling, kemudian data dianalisis dengan menggunakan uji Chi Square.
Hasil: pada penelitian ini didapatkan 39,1% kelompok kasus memiliki status gizi normal dan 78,3% kelompok kontrol memiliki status gizi normal. Pada uji Chi Square, menunjukkan terdapat hubungan yang bermakna antara status gizi dengan kejadian hiperemesis gravidarum (p=0,007, OR=5,600).
Kesimpulan: terdapat hubungan yang bermakna antara status gizi dengan kejadian hiperemesis gravidarum.
Hubungan Skor RMI Dengan Stadium Kanker Ovarium Tipe Epitel Di RSUP Dr. M. Djamil Padang
Authors: Mahyenda Nabilla , Muhammad Syamel , Asri Aswiyanti
Published: January 2023

Latar Belakang: Kanker ovarium menempati peringkat ketiga kejadian tertinggi kanker ginekologi di dunia maupun di Indonesia dengan subtipe epitel sebanyak 90% dari seluruh kasus kanker ovarium. Gejala klinis yang umumnya asimptomatik pada stadium awal dan baru terdeteksi pada stadium lanjut menyebabkan angka mortalitas yang cenderung tinggi pada kanker ovarium. Adanya suatu kombinasi modalitas preoperatif untuk mengevaluasi massa ovarium meliputi komponen ultrasonografi (USG), kadar CA-125, dan status menopause sebagai sebuah skor yang disebut dengan Risk Malignancy Index (RMI).
Objektif: Penelitian ini bertujuan untuk mengetahui hubungan antara skor Risk Malignancy Index dengan stadium kanker ovarium tipe epitel di RSUP Dr. M. Djamil Padang.
Metode: Penelitian ini merupakan penelitian analitik observasional dengan pendekatan cross sectional menggunakan data rekam medis pasien kanker ovarium tipe epitel di RSUP Dr. M. Djamil Padang tahun 2019-Juni 2021. Penelitian ini dilakukan selama bulan Maret sampai Oktober 2021. Analisis data dilakukan menggunakan uji Mann-Whitney.
Hasil: Didapatkan hasil skor RMI pada stadium lanjut lebih besar dibandingkan dengan stadium awal, dengan nilai p=0.045 (nilai p<0,05).
Kesimpulan : Terdapatnya hubungan yang bermakna antara skor RMI dengan stadium kanker ovarium tipe epitel di RSUP Dr. M. Djamil Padang.
Ocupação do espaço público: Uma proposta prefigurativa sob a urbanização capitalista neoliberal
Authors: Domingues Letícia Birchal
Published: January 2023

O artigo trata da ocupação do espaço público como proposta prefigurativa do comum em oposição ao neoliberalismo urbano. Articula as teorias urbana e política, baseando-se no ciclo global de protestos posterior à crise de 2008. Divide-se em três seções: i) relações entre urbano, capitalismo e práticas sociopolíticas; ii) fragmentações urbana, política e social; iii) ocupação dos espaços públicos, prefiguração e construção do comum.
Dessacramentalização sem dessacralização: A regulação judicial da (homo)conjugalidade no Brasil
Authors: Montero Paula , Nagamine Renata , Nicácio Camila , Borges Guilherme , Góes Luma
Published: January 2023

Este artigo analisa a decisão do STF a respeito da união estável entre pessoas do mesmo sexo. O reconhecimento jurídico dessas relações como união estável reabriu a discussão sobre o lugar do tempo na definição das condições que autorizam duas pessoas a se declararem cônjuges. A decisão deslocou para o centro do debate a historicidade (o caráter mutável) do instituto jurídico da família.
Socio-educational Aspects of Recreational Activities of a Youth Worker: Grounded Theory
Authors: Lisauskienė Dovilė , Aleksienė Vilmantė
Published: January 2023

The article, based on the analysis of the scientific literature and the strategy of the constructivist grounded theory, highlights the socio-educational aspects of the activities of a youth worker working with young people with fewer opportunities in the region. The first part presents the concept of recreation in the context of socio-educational work, revealing the prevailing perception of the concept of recreation in modern society. The second part highlights the specificity of the youth worker's activities by discussing the relationship between formal and non-formal work. The third part analyses the socio-educational aspects of the youth worker's activities in connection with the non-formal leisure environment and connection with the performed recreational activities. The results of the research showed that it is important to research socio-educational work through recreation and develop recreational activities in the youth social work.
Estudo do biocompósito de P3HB/nanodiamante para aplicação em dispositivos médicos, parte 2: citotoxicidade in vitro e testes de biocompatibilidade
Authors: Barros Junior Lucivan Pereira , Almeida Fabrício Moreira , Maia Yan Yucif Vieira Azevedo , Pereira Príscila Pinheiro
Published: January 2023

Na Parte 1 deste trabalho, foi apresentado um novo nanocompósito biodegradável e biocompatível com matriz polimérica de poli-hidroxibutirato (PHB) carregado com nanopartículas de diamante (ND) obtido, pela primeira vez, sob conhecimento dos autores, a partir da técnica de vaporização de solvente (técnica sob pedido de patente) para aplicação em acessórios médicos. As propriedades mecânicas, térmicas e morfológicas, como também a eficiência da técnica na homogeneidade e dispersão da carga na matriz polimérica confirmada através de modelos mecânicos  foram investigadas na Parte 1 do artigo. Na Parte 2, testes in vitro foram feitos para testar a citotoxicidade e biocompatibilidade do nanocompósito. Os testes resultaram na ausência de resposta inflamatória em culturas de fibroblastos e macrófagos para todas as composições do nanocompósitos estudados.
Avaliação do desempenho das companhias brasileiras de saneamento
Authors: Costa Mundim Bernardo , Junior Isaac Volschan
Published: January 2023

O artigo desenvolve uma avaliação do desempenho operacional e de qualidade dos modelos de prestação de serviços de abastecimento de água e esgotamento sanitário vigentes no Brasil. Preliminarmente, agruparam-se as diversas categorias de serviços de abastecimento de água e esgotamento sanitário em quatro grupos a partir das abrangências de atuação e das naturezas jurídico-administrativa estabelecidas pelo Sistema Nacional de Informações sobre Saneamento (SNIS). Em seguida, selecionaram-se indicadores de desempenho operacionais e de qualidade relevantes do SNIS, ano-base 2015. De posse dos valores dos indicadores para cada modalidade de prestação dos serviços, realizou-se uma caracterização prévia dos mesmos através de estatísticas descritivas básicas. Posteriormente, por meio da análise multicritério TOPSIS, classificaram-se os desempenhos das diversas modalidades de prestação dos serviços. Tais modalidades foram avaliadas e classificadas segundo os estratos populacionais usualmente empregados pelo Instituto Brasileiro de Geografia e Estatística. Os resultados demonstraram que as empresas privadas se destacaram nos dois primeiros estratos populacionais, enquanto a administração pública direta se sobressaiu no terceiro e a administração pública indireta no quarto. Conclui-se que: (i) o SNIS deve melhorar a qualidade do seu banco de dados; e, (ii) a utilização do Método TOPSIS satisfez ao objetivo pretendido, todavia, seus resultados devem ser analisados com criticidade.
Refractory anorexia nervosa in adulthood and nucleus accumbens deep brain stimulation
Authors: Lara-Almunia Monica , Aguirre-Orue Iratxe , Roset-Ferrer Carolina , Bermudez-Andion Carmen , Alvarez Ana Sofia , Mas-Bonet Antonio , Miguel-Pueyo Jose , Hernandez-Vicente Javier
Published: January 2023

Background:

Anorexia Nervosa is a life-threatening mental illness with numerous consequences. Some cases are chronic and refractory to multiple treatments. Consequently, there is great interest in therapeutic alternatives that may improve severe patients. We present an adult patient with anorexia nervosa that underwent to bilateral nucleus accumbens deep brain stimulation (NAc-DBS).

Case description:

The patient was a healthy 46-year-old woman with higher education and an adequate premorbid socio-labour situation. Her disease had a late onset (25 years). The patient never presented clinical remission or weight stability. In recent years, the patient’s body mass index (BMI) was 13.16 (32kg). The case was evaluated with multiple neuropsychological tests as well as the BMI before and after surgery. The clinical follow-up was 50 months. After bilateral NAc-DBS the patient experienced an important clinical benefit and significant improvement in neuropsychological tests and weight (BMI 17.28, 42 kg; 50th month) Programming: 4,5V, 130Hz, 210 µs.

Conclusion:

Despite the patient´s age and the long duration of the disease, our results suggest that bilateral nucleus accumbens stimulation may be a useful and effective therapeutic strategy for cases such as the one presented. Additionally, this case presents a surgical midlife patient with both the latest disease onset and the longest follow-up after treatment in the literature.
Factors associated with post traumatic hydrocephalus following decompressive craniectomy: A single-center experience
Authors: Jesuyajolu Damilola Alexander , Moti Terngu , Zubair Abdulahi Ajape , Alnaser Adnan , Zanaty Ahmed , Grundy Tom , Evans Julian
Published: January 2023

Background:

A decompressive craniectomy (DC) is a surgical procedure sometimes utilized to manage refractory intracranial hypertension following severe traumatic brain injury (sTBI). The previous studies have established a relationship between DC and post traumatic hydrocephalus (PTH). This study aimed to identify the factors responsible for developing shunt-amenable PTH in patients who underwent DC following sTBI.

Methods:

A review of a prospectively collected database of all patients admitted with severe TBI in a tertiary neurosurgical center in North-west England between January 2012 and May 2022 was performed. PTH was defined as evidence of progressive ventricular dilatation, clinical deterioration, and/or the eventual need for cerebrospinal fluid diversion (i.e., a ventriculoperitoneal shunt). Statistical analysis was carried out using IBM SPSS versus 28.0.1.

Results:

Sixty-five patients met the eligibility criteria and were included in the study. The mean age of the PTH group was 31.38 ± 14.67, while the mean age of the non-PTH group was slightly higher at 39.96 ± 14.85. No statistically significant difference was observed between the two groups’ mechanisms of traumatic injury (P = 0.945). Of the predictors investigated, cerebellar hematoma (and contusions) was significantly associated with PTH (P = 0.006).

Conclusion:

This study concludes that cerebellar hematoma (and contusions) are associated with developing PTH in patients undergoing DC.
Endoscopic cyclophotocoagulation in combined surgery of cataract and glaucoma
Authors:   Federal State Budgetary Educational Institution of Higher Education «Military Medical Academy named after S. M. Kirov», St. Petersburg., Kulikov A.N. , Skvortsov V.Y. ,   Federal State Budgetary Educational Institution of Higher Education «Military Medical Academy named after S. M. Kirov», St. Petersburg., Tulin D.V. ,   Federal State Budgetary Educational Institution of Higher Education «Military Medical Academy named after S. M. Kirov», St. Petersburg.
Published: January 2023

Background. Combined surgical treatment in patients with refractory glaucoma and cataract allows achieving stable compensation of intraocular pressure and a significant improvement in visual functions. Purpose. To study some aspects of efficacy and safety of combined endoscopic cyclophotocoagulation (ECP) with cataract phacoemulsification. Methods. 78 patients with uncompensated open-angle glaucoma at various stages were enrolled. They were treated with ECP and phacoemulsification. Among them there were 40 (51.28 %) men and 38 (48.72 %) women. The follow-up period was from 6 to 48 months. Mean age of the patients was 73.46 years. Results. At the end of the follow-up period, there was a significant decrease in mean IOP to 18.2±1.5 mm Hg, in comparison with the initial level of 24.1± 3.2 mm Hg (p<0.0001). At the same time, complete success was achieved in 46.6 % (34 eyes); qualified success (reduction of IOP to 21 mmHg and below) was achieved in 51.3 % (40 eyes). The number of topical glaucoma drugs has also significantly decreased from 2.5±1.0 to 1.9±1.0 (p = 0.001). Conclusion. ECP can be considered as a safe and effective antiglaucoma component of combined glaucoma and cataract surgery. Key words: glaucoma; transscleral laser cyclodestruction; endoscopic cyclophotocoagulation; microinvasive glaucoma surgery.
OCT imaging of occult flap retinal tear in posterior vitreous detachment
Authors:   Academy of postgraduate education of FSBU FSCC of FMBA of Russia, Moscow, Shaimova V.A. ,   «Center Zreniya», Chelyabinsk, Islamova G.R. ,   «Center Zreniya», Chelyabinsk, Kuchkildina S.K. ,   «Center Zreniya», Chelyabinsk, Dmukh T.S. ,   «Oculus» Сenter for Vision Correction, Krasnoyarsk, Kravchenko T.G. ,   Center оf Laser Medicine, Chelyabinsk
Published: January 2023

Changes in the posterior vitreous that look like hyperreflective dots are considered as a predictor of peripheral retinal breaks in acute posterior vitreous detachment (PVD), along with Shafer's sign, intraretinal and vitreous hemorrhages. Some of peripheral breaks in acute PVD remain unnoticed at the initial ophthalmoscopic examination due to poor visualization. We report a clinical case of an invisible peripheral retinal flap tear detection with overview wide-field OCT (RTVue XR Avanti, Line mode –12 mm) scanning by «sliding» method in the area of retinal hemorrhage in presence of multiple hyperreflective dots in the vitreous during acute symptomatic PVD. Key words: acute PVD; invisible flap tear; wide-field OCT; retinal hemorrhage; stardust sign; hyperreflective dots.
Innovative Probabilistic Vulnerability Investigation of Nuclear Power Plant Structures under Far-Field Ground Motion
Authors: Thakur Bhairav , Desai Atul , Shah Hemal , Kaushik Gondaliya
Published: January 2023

A structure's seismic fragility is the conditional collapse damage for a given seismic hazard level. This study established an earthquake level acceptable for the seismic performance and damage evaluations of a nuclear power plant's (NPP) reactor containment structure (RCS) in Surat, India. The RCS model's nonlinear studies were conducted using the finite element method (FEM). A series of nonlinear time-history simulations were also applied to observe the top of the RCS dome. Probabilistic seismic demand models for each intensity measure (IM) of RCS were constructed (IM). This study summarises several guidelines and techniques related to the damage analysis of nuclear facilities. The linear regression method uses incremental dynamic analysis results to produce the fragility curve. The analytical studies concluded that the nuclear reactor has a 50 per cent chance of slightly collapsing at 0.87g of RCS.
Green Synthesis of Ceiba pentandra copper nanoparticles and their characterization
Authors: Riazunnisa K. , Rajesh N. , Chandrasekhar T. , Anu Prasanna V. , Subhosh Chandra M.
Published: January 2023

In the present study, Ceiba pentandra (CP) aqueous leaf extract was used for the synthesis of copper nanoparticles (CuNPs). Techniques like UV-visible spectrophotometer, SEM, EDX, XRD and in vitro antioxidants assay were used to characterize synthesized nanoparticles. UV-Visible spectrophotometer showed absorbance peak at 310 nm. SEM analysis demonstrated that the CuNPs are spindly shaped structures with average size of about 62.63nm. XRD analysis revealed the face centered cubic like structures of CuNPs. Ceiba pentandra copper nanoparticles (CP-CuNPs) exhibited good in vitro antioxidant activities i.e. 80 % inhibition of free radicals with DPPH assay, 70% inhibition of H2O2 with hydrogen peroxide scavenging assay and 75% inhibition in phosphomolybdenum assay compared to leaf extract. Hence the above protocol is a humble, fast, environmentally friendly, non-hazardous and an alternative for physical/chemical methods.
Photodegradation of Methylene Blue by Nano-Titania developed from Novel Heteroleptic Titanium(IV) Complexes
Authors: Thanigachalam Sathish , Pathak Madhvesh
Published: January 2023

Three new heteroleptic mononuclear derivatives of titanium(IV) have been synthesised and characterized by physico-chemical techniques. The newly synthesised titanium complexes [C26H21Br2NO5Ti] 1, [C26H21Cl2NO5Ti] 2 and [C26H21F2NO5Ti] 3 were obtained by treating [Ti(OPri)4] with 8-hydroxyquinoline, acetylacetone and corresponding phenol derivatives in 1:1:1:2 stoichiometry while refluxing in benzene as a reaction solvent under anhydrous stringent conditions. The newly synthesised titanium(IV) complexes were established by NMR (1H and 13C), FTIR and HRMS. Derivative 1 was employed as a precursor for the synthesis of nano titania by sol-gel method. The morphology of TiO2 was confirmed by several analytical tools such as FTIR, powder XRD, UV-Vis, RAMAN, SEM and TEM analyses. Further, the nano-structured titanium oxide developed herein was exploited to evaluate the catalytic photodegradation of methylene blue dye in aqueous solution on illumination of UV light that resulted in the extent of decolourization up to 68%, 81% and 94% by taking 20, 30 and 40 mg of catalyst in account respectively.
Mechanochemical route for carboxy substituted Schiff-Base polymer coated MWCNT composite as an efficient adsorbent for the removal of Methylene Blue dye: Kinetics, Isotherms and Thermodynamic studies
Authors: Shivarathri Poornima Gubbi , Rajappa Shwetha , Devendrachari Mruthyunjayachari Chattanahalli , Kotresh Harish Makri Nimbegondi
Published: January 2023

In the present investigation, we report a rapid and green mechanochemical approach for the synthesis of carboxy substituted Schiff-Base polymer (cPSB) and MWCNT coated with cPSB composite (cPSB@MWCNTs) as an efficient adsorbent for cationic methylene blue MB dye. The as-synthesized cPSB and cPSB@MWCNTs were characterized by Fourier-transformed infrared spectrometer (FTIR), X-ray diffraction (XRD) and Scanning electron microscopy (SEM) to analyze the structure, size and morphology. Effects of different variables such as catalyst loading, contact time, effect of initial dye concentration and pH of the medium during the process of dye adsorption were studied. Adsorption was in agreement with the pseudo-second-order and is a chemisorption process according to the kinetic analysis. The adsorption equilibrium data for the dye adsorption process fitted well with the Langmuir model. In cPSB@MWCNTs, the removal efficiency of MB was found to be 99 % in 90 min at pH 7. The adsorption of dyes on cPSB@MWCNTs from thermodynamic data was found to be spontaneous and endothermic with a continuous decrease in entropy. Further cPSB@MWCNTs composite demonstrated admirable maximum adsorption capacity towards both MB (96.9 mg g−1) indicating cPSB@MWCNTs as an efficient cationic dye adsorbent.
Isolation, characterization and decolourization of Nano-curcumin for cosmetic industry
Authors: Sonawane Pramod , Meroliya Heena
Published: January 2023

Curcuminoids are one of the naturally occurring yellow pigments which consist of curcumin, dimethoxy curcumin and bisdimethoxy curcumin. Curcuma longa rhizome have been popularly used in traditional medicine and to some extent, it is one of the active ingredients in drugs. In this study, crude extract of curcuminoids was extracted from turmeric using various extraction techniques. The isolation of curcumin and separation of oil and resin was carried out by using different solvents of polar and nonpolar nature. We present here the study comprising of extraction of curcumin by various traditional methods and synthesis of nano-curcumin by green sonochemical method using natural Neem leaves extracts. The XRD images show that nano-curcumin of crystallite size as small as 28 nano meters is formed whereas decolorized curcumin synthesized by peroxide method shows crystallite size of 21 nm. A simple method of decolorization of nano curcumin using peroxide is explained. The 1H NMR of the same sample shows that during the decolourisation process, there is no observable change in structure but only change in colour from curcumin dark yellow to very pale yellow colour is observed.
Synthesis of novel 5-(4-N-Alkyl-piperazin-1-yl)-1-benzofuran-2-yl)-3-substituted phenyl propenone derivatives as antibacterial agents: In vitro and In silico studies
Authors: Krishnaswamy G. , Desai Nivedita R. , Raja Naika H. , Sreenivasa S. , Aruna Kumar D.B.
Published: January 2023

The present study aimed at the synthesis and in vitro as well as in silico evaluation of novel 5-(4-N-alkyl-piperazin-1-yl)-1-benzofuran-2-yl)-3-substituted phenyl propenone [3a-f] derivatives as antibacterial agents. The structures of newly synthesized compounds were characterized by spectroscopic techniques such as FT-IR, 1HNMR and mass spectrometry. Finally, the newly synthesized derivatives were screened for their in vitro antibacterial activities and exhibited weak to moderate activity. N-alkyl piperazine benzofuran derivatives exhibited good activity while their corresponding chalcone derivatives showed enhanced antibacterial activity. In correlation to in vitro results, molecular docking study was performed on target protein GlcN-6-P synthase using Autodock 4.2. The in silico studies reveal that compounds have more binding affinity towards the receptor.
Removal of Heavy Metals from Industrial Wastewater using Low-Cost Waste Materials
Authors: Lakshmi M. , Ranjitha J.
Published: January 2023

The most serious environmental problem in the world is heavy metal pollution due to industrialization and urbanization. A special concern is to be taken for the removal of heavy metals in the environment. In developing countries, the price effectiveness might be a major factor in the removal of heavy metal toxicity which is a major threat to the environment for several decades. In this study, heavy metal contamination of water bodies has been reviewed here. The toxic effluents from the textile industry, shredding facilities, glass industry, metal industry, refinery, automobile industry, pharmaceutical industry, semiconductor industry, printing industry, catering industry landfill leakage contain a huge amount of heavy metals in their waste. The conventional methods are very expensive, energy-intensive and sometimes generate a toxic byproduct. The current review focuses on the adsorption technique of heavy metals removal using different adsorbent materials from waste naturally. Numerous low-cost adsorbents are widely used such as garlic peel, jack fruit peel, oil palm trunk fiber, rice bran and wheat bran, broad bean peel, groundnut shell, raw agricultural solid waste, papaya seeds, leaf biomass etc. explored for the removal of toxic heavy metal from wastewater. These absorbents materials naturally have their origin by themselves such as zeolites, clay, sphagnum moss and polysaccharide which are found to be efficient agents for the removal of toxic metals like lead Cd, Zn, Cu, Ni, Hg, Cr, etc. Numerous agricultural wastes like rice husk, neem bark, black gram, waste tea-coffee, walnut-shell, coconut coir, coconut husk, bagasse etc., are widely used for the heavy metal removal in a sustainable nature.