bluuebunny/crossref_metadata_2025 huggingface dataset:
Improving Approaches to Implementing Regional Development Strategy based on Reducing Intra-Regional Differentiation
Authors: Pankova Yu. V.
Published: March 2024

The heterogeneity of economic space is its natural property. At the same time, high levels of inequality can become a threat to the integrity of the socio-economic system and cause its slower development. In this regard, the problem of uneven spatial development is relevant for spatially extended economies (both national and regional) and is reflected in strategic planning documents. This article is devoted to the issues of spatial development of the largest subject of the Russian Federation – the Republic of Sakha (Yakutia), – whose socio-economic development strategy notes increased intra-regional differentiation and disunity of economic zones, which is classified as the main challenges to the spatial development of the region. At the same time, this strategy does not highlight a list of measures to reduce the difference in the level of development of municipal districts, and also does not indicate the consequences of the implementation of the activities and projects planned by the strategy in the context of the spatial development of the region and its unevenness. In this paper in the context of municipal districts, an assessment was made of the effects of the implementation of large investment projects in the mining sector, which, according to the development strategy of the Republic of Sakha (Yakutia), will remain the main source of economic growth in the region. The study was conducted using a regional intersectoral model taking into account multiplier effects and spatial heterogeneity. Based on the obtained estimates, it is shown that the implementation of raw materials projects can cause an increase in intra-regional differentiation of economic development. The possibility of shrinking the economic space of the region in the absence of measures to equalize imbalances is noted. As a compensatory mechanism for the spatial heterogeneity of effects, an increase in the localization of effects from the implementation of these projects in various areas (localization of production, employment, redistribution of the part of the rent withdrawn from the extractive sector to the tasks of spatial development of the region) is considered.
Serous surface papillary borderline tumor of ovary – An underdiagnosed entity
Authors: Kaushik Anuradha , Panda Ananya , Verma Vikrant , Nalwa Aasma , Ghuman Navdeep Kaur
Published: March 2024

A young female presented with complaints of dysmenorrhea for 8 months. Ultrasound of the pelvis showed an echogenic mass in the left adnexa with papillary projections and internal vascularity and encasing the left ovary. Subsequent magnetic resonance imaging (MRI) showed an intensely enhancing, lobulated solid mass with a frond-like appearance, and papillary projections surrounding the left ovary reminiscent of a “sea-anemone.” The right ovary showed a cystic lesion without enhancing papillary projections or mural nodules. There was mild pelvic ascites and few peritoneal nodules in the pelvis. The presumptive radiologic diagnosis was serous surface papillary borderline tumor (SSPBT) of the left ovary and a benign cyst in the right ovary. The patient was treated with the left salpingo-oophorectomy, right ovarian cystectomy, peritoneal, and omental biopsies. Histopathology confirmed the diagnosis of SSPBT of the left ovary with microinvasion (<5 mm) of the ovarian surface. The right ovarian cyst was a follicular cyst. The peritoneal biopsies were positive for implants from SSPBT. This report highlights the diagnostic utility of “sea-anemone” sign and reviews the clinical and radiopathologic features of SSPBT.
Unusual aggressive central nervous system involvement in CLIPPERS syndrome
Authors: Kahraman Osman , Ermiş Abdulkadir , Karaalioğlu Banu
Published: March 2024

Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids known as CLIPPERS syndrome is a rare and recently described inflammatory disorder of the central nervous system. Ataxia and cognitive dysfunction are usual symptoms and are dramatically responsive to steroid treatment. We present a case of a 58-year-old female patient, clinically diagnosed CLIPPERS syndrome with unusual aggressive involvement of supratentorial white matter and spinal cord that showed complete recovery with significant atrophy after steroid therapy.
Retour vers le perceptron - fabrication d’un neurone synthétique à base de composants électroniques analogiques simples
Authors: ORLIANGES Jean-Christophe , El Moustakime Younes , Crunteanu STANESCU Aurelian , Carrizales Juarez Ricardo , Allegret Oihan
Published: March 2024

Les avancées récentes dans le domaine de l'intelligence artificielle (IA), en particulier dans la reconnaissance d'images et le traitement du langage naturel, ouvrent de nouvelles perspectives qui vont bien au-delà de la recherche académique. L'IA, portée par ces succès populaires, repose sur des algorithmes basés sur des "réseaux de neurones" et elle se nourrit des vastes quantités d'informations accessibles sur Internet, notamment via des ressources telles que l'encyclopédie en ligne Wikipédia, la numérisation de livres et de revues, ainsi que des bibliothèques de photographies. Si l'on en croit les propres dires du programme informatique ChatGPT, son réseau de neurones compte plus de 175 millions de paramètres. Quant à notre cerveau, qui était le modèle initial de cette approche connexionniste, il compte environ 86 milliards de neurones formant un vaste réseau interconnecté... Dans ce travail, nous proposons une approche plus modeste de l'IA en nous contentant de décrire les résultats que l'on peut obtenir avec un seul neurone synthétique isolé, le modèle historique du perceptron (proposé par Frank Rosenblatt dans les années 1950). C'est un "Retour vers le futur" de l'IA qui est entrepris pour fabriquer et tester un neurone artificiel à partir de composants électroniques simples. Celui-ci doit permettre de différencier un chien d'un chat à partir de données anatomiques collectées sur ces animaux.
New insights in the mechanism of the SARS-CoV-2 Mpro inhibition by benzisoselenazolones and diselenides
Authors: Sancineto Luca , Mangiavacchi Francesca , Dąbrowska Agnieszka , Pacuła Agata , Obieziurska-Fabisiak Magdalena , Ceccucci Veronica , Scimmi Cecilia , Kong Juan , Zhao Yao , Ciancaleoni Gianluca , Nascimento Vanessa , Rizzuti Bruno , Kula-Pacurar Anna , Yang Haitao , Ścianowski Jacek , Lei Ying , Pyrc Krzysztof , Santi Claudio
Published: March 2024

Although global vaccination campaigns relieved the SARS-CoV-2 pandemic in terms of morbidity and mortality, the capability of the virus to originate mutants may reduce vaccines efficiency, posing a serious risk to fall into the pandemic again. As a result, there is the need to develop small molecules able to tackle conserved viral targets, such as the main protease (Mpro). Here a series of benzisoselenazolones and diselenides were tested for their ability to inhibit Mpro, then, for the most potent compounds, the antiviral activity was measured in vitro, and the mechanism of action was investigated. Density functional theory and molecular docking procedures were also implemented to shed a light into the protein/compound interaction. Finally, a bioorganic model was set up to investigate the reaction between selenorganic compounds and biologically relevant thiols, to unravel possible metabolic pathways of such compounds. The overall results contribute to identify a series of novel compounds active against SARS-CoV-2, and to clarify some important aspects in the mechanisms of action of Se-containing inhibitors targeting the SARS-CoV-2 main protease (Mpro).
End-to-End High-Throughput Approach for Data-Driven Internal Donor Development in Heterogeneous Ziegler-Natta Propylene Polymerization
Authors: Taniike Toshiaki , Cannavacciuolo Felicia Daniela , Khoshsefat Mostafa , De Canditiis Diego , Antinucci Giuseppe , Chammingkwan Patchanee , Cipullo Roberta , Busico Vincenzo
Published: March 2024

Internal donors (IDs) play a decisive role in shaping the structure and performance of Ziegler-Natta catalyst formulations for the isotactic polypropylene production. Unfortunately, their diverse and intricate functions remain elusive, and rational ID discovery therefore is still problematic. Exploitation of artificial intelligence methods such as machine learning, in turn, has been hindered by the lack of training datasets with adequate quality and size. This study proposes an integrated high-throughput workflow encompassing catalyst synthesis, propylene polymerization, and polypropylene characterization. Its application to an ID library of 35 molecules generated a robust and consistent dataset, which highlighted important and intriguing quantitative structure-properties relations (QSPRs). Furthermore, by fingerprinting ID molecular structure in combination with feature selection, a black-box QSPR model correlating ID molecular structure and catalytic performance was successfully implemented. This study demonstrates that the combination of high-throughput experimentation and machine learning is a promising asset for accelerating the research and development of Ziegler-Natta catalysts.
A Study of Strain and Electric Field Induced Photocatalytic Crossover in g-C3N4/CoN4 Nanocomposite through DFT : Upgradation from Type-I to Type-II Photocatalyst for Water Splitting Reaction
Authors: N Dhilshada. V. , Sen Sabyasachi , Chattopadhyaya Mausumi
Published: March 2024

Van der Waals (vdW) heterojunctions, consisting of two-dimensional monolayers, represent a recent category of materials characterized by their highly adjustable band alignment, bandgap energy, and bandgap transition characteristics. In this investigation, we employed density functional theory calculations to explore the formation of a vdW heterojunction involving heptazine-based graphitic carbon nitride (g-C3N4) monolayer and CoN4 (111) slab, denoted as g-C3N4/CoN4. This specific heterojunction holds promise as a potential catalyst for solar-driven photocatalysis in the water-splitting reaction. Upon the creation of the heterojunction, a type-I direct bandgap (Eg = 2.00 eV) is established, featuring appropriate conduction band minimum and valence band maximum levels in relation to the oxidation/reduction potentials for the water-splitting reaction. Moreover, the band alignment, bandgap energy, and transition type of the heterojunction can be tuned finely by applying external perpendicular electric fields (±0.5 V/Å) and biaxial strains of (±6 %). Notably, a -2% strain induces a type-II band alignment (Eg = 2.1 eV, direct), while an electric field of +0.5 V/Å also results in a type-II heterostructure (Eg = 1.90 eV, direct). The state-of-the-art DFT study reveals a photocatalytic crossover in g-C3N4/CoN4 from type-I to type-II in presence of bilateral strain and electric field.
Stability and Structure of Potentially Atmospherically Relevant Glycine Ammonium Bisulfate Clusters
Authors: Hariharan Annapoorani , Bready Conor J. , Ajello Jack G. , Black Samantha H. , Shields George C. , Johnson Christopher J.
Published: March 2024

New particle formation (NPF) is the process by which trace atmospheric acids and bases cluster and grow into particles that ultimately impact climate. Sulfuric acid concentration drives NPF, but nitrogen-containing bases promote the formation of more stable clusters via salt bridge formation. Recent computational efforts have suggested that amino acids can enhance NPF, predicting that they can stabilize new particles via multiple protonation sites, but there has yet to be experimental validation of these predictions. We used mass spectrometry and infrared spectroscopy to study the structure and stability of cationic clusters composed of glycine, sulfuric acid, and ammonia. When collisionally activated, clusters were significantly more likely to eliminate ammonia or sulfuric acid than glycine, while quantum chemical calculations predicted lower binding free energies for ammonia but similar binding free energies for glycine and sulfuric acid. These calculations predicted several low-energy structures, so we compared experimental and computed vibrational spectra to attempt to validate the computationally-predicted minimum energy structure. Unambiguous identification of the experimental structure by comparison to these calculations was made difficult by the complexity of the experimental spectra and the fact that the identity of the computed lowest-energy structure depended strongly on temperature. If their vapors are present, amino acids are likely to be enriched in new particles by displacing more weakly-bound ammonia, similar to the behavior of other atmospheric amines. The carboxylic acid groups were found to preferentially interact with other carboxylic acids, suggesting incipient organic/inorganic phase separation even at these small sizes.
Friedel-Crafts Reactions for Biomolecular Chemistry
Authors: Ohata Jun
Published: March 2024

Chemical tools and principles have become central to biological and medical research/applications by leveraging a range of classical organic chemistry reactions. Friedel-Crafts alkylation and acylation are arguably one of the most well-known and used synthetic methods for preparation of small molecules but its use in biological and medical fields are relatively less frequent than the other reactions, possibly owing to the notion about its plausible incompatibility with biological systems. This Review demonstrates advances of Friedel-Crafts alkylation and acylation reactions in a variety of biomolecular chemistry fields. With the discoveries and applications of numerous biomolecule-catalyzed or –assisted processes, the reactions have garnered considerable interests in biochemistry, enzymology, and biocatalysis. Despite the challenges of reactivity and selectivity of biomolecular reactions, the alkylation and acylation reactions demonstrated its utility for construction and functionalization of all the four major biomolecules (i.e., nucleosides, carbohydrates/saccharides, lipids/fatty acids, and amino acids/peptides/proteins), and their diverse applications in biological, medical, and material fields are discussed. As the alkylation and acylation reactions are often fundamental educational components of organic chemistry courses, the Review is intended for both experts and nonexperts by discussing their basic reaction patterns (with the depiction of each reaction mechanism in the Electronic Supplementary Information) and relevant real-world impacts in order to enrich chemical research and education. The significant growth of biomolecular Friedel-Crafts reactions described here is a testament to its broad importance and utility, and the further development and investigation of the reactions will surely be the focus in the organic biomolecular chemistry fields.
Accessing active fragments for drug discovery utilising nitroreductase biocatalysis
Authors: Holder Lauren , Yuce Eda , Oriomah Gabriel , Jenkins Aimee , Reynisson Jóhannes , Winter Anja , Cosgrove Sebastian
Published: March 2024

Biocatalysis has played a limited role in the early stages of drug discovery. This is often attributed to the limited substrate scope of enzymes not affording access to vast areas of novel chemical space. Here, we have shown a promiscuous nitroreductase enzyme (NR-55) can be used to produce a panel of functionalised anilines from a diverse panel of aryl nitro starting materials. After screening on analytical scale, we show that sixteen substrates could be scaled to 1 mmol scale, with several poly-functional anilines afforded with ease under the standard conditions. The aniline products were also screened for activity against several cell line of interest, with modest activity observed for one compound. This study demonstrates the potential for nitroreductase biocatalysis to provide access to functional fragments under benign conditions.
Development of polyresistance in microorganisms during antibiotic therapy in a multidisciplinary hospital during a pandemic COVID-19
Authors: Esaulenko Nikolay B. , Tkachenko Olga V. , Kazakov Sergey P. , Davydov Denis V. , Zaytsev Andrey A. , Chernov Sergey A.
Published: March 2024

Background. Irrational and excessive use of antimicrobials drugs (AMD) creates conditions for the development of a global crisis of health systems around the world associated with antibiotic resistance.
Aim. To conduct a retrospective study of the impact of the use of AMD on the change in the microbiological landscape and the sensitivity of microorganisms in the conditions of pandemic of the new coronavirus infection (COVID-19) in 2020–2021 in intensive care departments (ICD) of a multidisciplinary hospital.
Materials and methods. In the course of the work, strains of microorganisms isolated from patients and from the surfaces of the hospital environment and changes in their sensitivity to significant groups of AMD in ICD for somatic and infectious patients with COVID-19 were compared. The sensitivity of the isolates was evaluated in accordance with the criteria of requirements of European Committee on Antimicrobial Susceptibility Testing – EUCAST, version 10.0, 2020.
Results. A total of 1,394 isolates were studied, including 1,379 clinical and 15 isolates from the surfaces of the hospital environment. It was found that in all ICD in 2020–2021, gram-negative microorganisms prevailed in infectious loci in 70% of cases or more. In 2021, in the ICD in infectious patients with COVID-19, the persistent dominance of the Acinetobacter baumannii microorganism was revealed with an increase in the number of poly- and pan-resistant strains – 48.7%. While in the ICD for somatic patients Klebsiella Pneumoniae prevailed among gram-negative microorganisms – 37.5% in 2020 and 43.7% in 2021. It has been shown that in one department or in adjacent departments of the same medical institution, various nosocomial microorganisms with an unequal set of resistance genes and sensitivity to AMD may appear over time.
Conclusion. The necessity of conducting constant microbiological monitoring and a passport of the medical department with mandatory registration of not only isolated strains of microorganisms, but also resistance genes in order to optimize the appointment of timely adequate empirical antimicrobial therapy is substantiated. The period of the latter should be as short as possible, and confirmed by convincing clinical signs of bacterial infection, and subsequently by the isolation of nosocomial flora from the biomaterial of critical loci from patients.
Factibilidad del uso del BTC, en la parroquia Cojitambo; del cantón Azogues.
Authors: Beltrán Rodríguez Miriam Camila , Venegas Tomalá Andrés Oswaldo
Published: March 2024

El presente trabajo tiene como objetivo comprobar la factibilidad del uso de BTC, en la parroquia Cojitambo, del cantón Azogues, con la finalidad de validar sus propiedades para la fabricación de un material sostenible, que se compone con la materia prima propia del lugar; por lo tanto, se analizan diversas normas internacionales referentes al bloque de terrocemento, seleccionando aquellas que presenten mayores similitudes climáticas y geográficas que el lugar de estudio, puesto que serán aplicadas a cuatro suelos extraídos de diferentes zonas, que fueron establecidas mediante la sectorización de construcción en tierra en la parroquia. Asimismo, se describen diferentes ensayos que exigen las normativas, con la finalidad de verificar la calidad de cada muestra de tierra, para tener mayor certeza en la fabricación del bloque, cada BTC debe cumplir con los estándares necesarios, para someterlos a ensayos de: resistencia, absorción y capilaridad. Por ultimo, se realiza un análisis de los resultados obtenidos, y se compara su resistencia con la de mampuestos comúnmente utilizados en el medio como es el ladrillo y bloque pómez. Se concluye que es posible la utilización del bloque de terrocemento en las cuatro zonas de la parroquia, debido a que se demuestra la aptitud del material propuesto.
Çocuk Yazınında Aşk Teması: Peter Härtling’in “Benjamin Anna’yı Seviyor” Romanındaki Aşk Söyleminin İncelenmesi
Authors: CENGİZ Nurel
Published: March 2024

Çocuklar için yazılan eserlerin geçmişten günümüze yetişkinlerin bakış açılarından hareketle didaktik bir söylemle yazılması, bu eserlerinin gerçekten çocuğun beklentisini ne ölçüde karşıladığı sorusunu beraberinde getirmektedir. Neyin yazılacağına, basılacağına, çevrileceğine ve hatta satın alınacağına yetişkinler karar vermiştir. 1970’li yıllarda Almanya’da çocuk yazınında sınırlar aşılmış; aşk, ebeveynlerin boşanması, çeşitli bağımlılıklar gibi daha önce çocuk yazınında yer almayan konular işlenmeye başlanmıştır. Peter Härtling’in romanı Ben liebt Anna 1979 yılında yazılmış ve büyük beğeni toplamıştır. Roman, 1980 yılında Zürih Çocuk Kitabı Ödülü’nü kazanmış ve 1991 yılında Necdet Neydim tarafından Türkçeye çevrilmiştir. Tabu bir konuyu ele alması açısından erek metindeki çeviri stratejisi önem arz etmektedir. Kültürlerarası iletişimi sağlayan bir olgu olan çeviri, sansür söz konusu olduğunda bu aktarıma ket vurabilmektedir. Sansürün nedenleri siyasi, kültürel veya ideolojik olabilir. Erek kültürde tabu sayılan müstehcen veya erotik sahnelerin sansürlenmesi de olasıdır. Bu bağlamda edebi dizgeyi kabul görmüş toplumsal normların dışına çıkmaması için kontrol eden ikili bir etmen bulunmaktadır. Bunlar çevirmen, eleştirmen ve araştırmacıların yer aldığı birinci grup ile dizgeyi dışarıdan kontrol eden medya, eğitim kurumları, siyasi partiler ve yayınevleri gibi patronaj olarak bilinen güç odaklarıdır. Çocuk yazınında farklı bir kültürel bağlama sahip erek kitle için kültürel uyarlama yapmak gerekebilir. Ancak tüm kültürel bağlamın uyarlanması, çocuğun kültürlerarası kaynaşma fırsatı yakalamasını engelleyebilir. İncelenen romanın çevirisinin yukarıda bahsedilen manipülasyon ve sansürden uzak olması ve erek kitle için herhangi bir uyarlamaya maruz kalmaması, ülkemizdeki çeviri çocuk yazını için alışılmamış bir durumdur. Bu çalışmada erek metindeki aşk söylemi Alvstad’ın çocuk yazını çevirisinde altını çizdiği kültürel uyarlama ve ideolojik manipülasyon özelinde incelenmiştir.
Las comunidades indígenas de Hidalgo. Ixmiquilpan Volumen II
Authors: Quezada Ramírez María Félix
Published: March 2024

Como resultado del proyecto catálogo de pueblos y comunidades indígenas del Estado de Hidalgo, este documento reúne las monografías de algunas localidades de Ixmiquilpan que fueron visitadas entre marzo a septiembre de 2013.
Las comunidades indígenas de Hidalgo Zimapán vol. III
Authors: Pizarro Hemández Karina
Published: March 2024

El presente trabajo es parte del proyecto Catálogo de comunidades indigenas del Estado de hidalgo ha involucrado a diversas instituciones del estado, entre ellas a la Universidad Autonoma del Estado de Hidalgo , al Congreso del Estado de Hidalgo con la XLI legislatura, a la comision de Desarrollo de los pueblos Indigenas en su Delegacion Hidalgo y al Poder Ejecutivo a traves del Gobierno del Estado.
PERANAN KEPEMIMPINAN KEPALA SEKOLAH DALAM PENGEMBANGAN LEMBAGA DAN PENINGKATAN MOTIVASI GURU SEKOLAH PENGGERAK
Authors: Holdi Muhammad , Mulyono Sugeng , Gunadi Gunadi , Sulaiman Sulaiman
Published: March 2024

The objectives of this research are: i) To explore and describe the role of school principals in developing institutions and increasing the motivation of driving school teachers in East Lombok Regency. ii) To explore and describe the challenges and opportunities for school principals in developing institutions and increasing the motivation of driving school teachers in East Lombok Regency. ii). This research is a type of field research with a descriptive quantitative approach. The population in this study was 324 people consisting of 24 school principals and 300 teachers in elementary school education units. The sample in this study were 10 elementary school principals and 22 teachers who ran the Driving School Program in East Lombok Regency. The data analysis technique used in this research is the percentage technique. The research results show that; (i) The leadership role of school principals in developing institutions at driving schools in East Lombok Regency is at 85,0%. and entered the "Very Good" criteria, (ii) The Leadership Role of School Principals in Increasing the Motivation of Motivating School Teachers obtained a figure of 79.2% and entered the "Very Good" category.
GAYA KEPEMIMPINAN, BUDAYA ORGANISASI, MOTIVASI DAN KINERJA PENDIDIK SMK NEGERI DI LOMBOK TIMUR
Authors: Muhardi Muhardi , Muawanah Umi , Farhan Djuni
Published: March 2024

This study was meant 1) to partially analyze the influence of leadership style, organizational culture and motivation on the performance of Educators in State Vocational High Schools in East Lombok Regency. 2) to analyze whether the variables of leadership style, organizational culture and motivation simultaneously influence the performance of Educators in State Vocational High Schools in East Lombok Regency. 3) to analyze the variables of leadership style, organizational culture and motivation, which variables had the most dominant influence on the performance of Educators in State Vocational High Schools in East Lombok Regency. This study was a causal associative research. This study was also a population research where the respondents who returned the questionnaire were 78 respondents. Quantitative analysis technique was used in this study along with the assistance of the SPSS 20 aplication. It showed that 1) Leadership Style had a positive influence on the performance of educators. 2) Organizational culture had a positive influence on the performance of educators but was not significant. 3) Motivation had a positive influence on the performance of educators. 4) Leadership Style, Organizational Culture and Motivation simultaneously influence on the Performance of Educators. 5) Among the three independent variables, motivation variable had the most dominant influence in improving the performance of Educators in State Vocational High Schools in East Lombok Regency.
KECERDASAN EMOSIONAL, LINGKUNGAN KERJA, DISIPLIN KERJA DAN PRODUKTIVITAS KERJA GURU SD DI LOMBOK TIMUR
Authors: Parhanuddin Parhanuddin , Hadiyati Ernani , Muawanah Umi
Published: March 2024

This study aimed at 1) analyzing partially the influence of emotional intelligence, work environment, and work discipline on the work productivity of Educators in State Elementary Schools in West Sakra District. 2) analyzing whether the variables of emotional intelligence, work environment, and work discipline simultaneously influence on the work productivity of Educators in State Elementary Schools in West Sakra District. 3) analyzing the variables of emotional intelligence, work environment, and work discipline, which variables had the most dominant influence on the work productivity of Educators in State Elementary Schools in West Sakra District. This study was a causal associative research. This study was also a population study where the number of respondents who returned the questionnaire was 105 respondents. Quantitative analysis technique was used in this study with the assistance of SPSS 20. This study showed that 1) Emotional Intelligence had a positive influence on the productivity of the performance of educators in State Elementary Schools in West Sakra District. 2) The work environment had a positive influence on the productivity of the performance of educators at State Elementary Schools in West Sakra District. 3) Work Discipline had a positive influence on the productivity of the performance of educators at State Elementary Schools in West Sakra District.
PENEMPATAN KERJA, KARAKTERISTIK PEKERJAAN DAN KEPUASAN KERJA PEGAWAI SEKRETARIAT DPRD LOMBOK TIMUR
Authors: Aida Yusron , Mulyono Sugeng , Gunadi Gunadi , Sulaiman Sulaiman
Published: March 2024

The aim of this research is to prove and analyze the influence of job placement and job characteristics on job satisfaction of East Lombok Regency DPRD Secretariat employees. The type of research used is explanatory research. The analysis technique is carried out using multiple linear regression. The results of this research are that partially, work placement and job characteristics have a significant effect on job satisfaction of East Lombok Regency DPRD Secretariat employees. Likewise, simultaneously, work placement and job characteristics influence the job satisfaction of East Lombok Regency DPRD Secretariat employees with an influence contribution of 41.2%.
PENGARUH PENGGUNAAN MULTIMEDIA SMART TV TERHADAP KEAKTIFAN BELAJAR SOSIOLOGI SISWA SMA NEGERI 3 BULUKUMBA
Authors: Torro Supriadi , Irwansyah Idham , Aini Syarifah
Published: March 2024

The purpose of this study is to find out: 1) Overview of smart TV multimedia learning media in the field of sociology studies at UPT SMA Negeri 3 Bulukumba. 2) Overview of student learning activity in the field of sociology at UPT SMA Negeri 3 Bulukumba. 3) The influence of the use of smart TV multimedia media on student learning activity in the field of sociology studies at UPT SMA Negeri 3 Bulukumba. This study used a type of quantitative research with a descriptive approach, the total population in this study was 126 people. The process of determining the sample size using propability sampling techniques, namely proportionate stratified random sampling which is determined through the Slovin formula and obtained a sample number of 97 people. Data collection techniques in the form of questionnaires and documentation. Validity test using Bivariate Person correlation technique and reliability test using Alpha Cronbach. Data analysis techniques use descriptive statistics and inferential statistical analysis through the help of IBM SPSS Statistics application version 25 for Windows.The results of this study show that: 1) The description of multimedia smart TV learning media in the field of sociology studies at UPT SMA Negeri 3 Bulukumba is in the "high" category which shows the average score value (mean) of multimedia smart TV variables of 76.51 whose percentage rate is 76.50%. 2) The description of student learning activity in the field of sociology at UPT SMA Negeri 3 Bulukumba occupies the "high" category which shows the average value of student learning activity variables is 97.40 with a percentage rate of 77.92%. 3) There is an influence between multimedia variables smart TV on variables of student learning activity at UPT SMA Negeri 3 Bulukumba. This statement is evidenced from the significance value of 0.000<0.05 and the calculated value of 12.146 > t table 1.66071, so that the acquisition shows that variable X has an effect on variable Y. Then to find out the magnitude of the influence value between the two variables can be obtained from the R Square value of 0.608 which means that the multimedia smart TV variable (X) affects student learning activity (Y) simultaneously by 60.8% and the remaining 39.2% is influenced by other factors Outside of research.
KUALITAS KEHIDUPAN KERJA, KEPEMIMPINAN DAN KEPRIBADIAN SERTA EMPLOYEE ENGAGEMENT PERANGKAT DESA DI KECAMATAN LABUHAN HAJI
Authors: Paelori Daeng , Mulyono Sugeng , Suswati Endang , Sulaiman Sulaiman
Published: March 2024

This research aims to prove and analyze the influence of quality of work life, leadership and personality on employee engagement of village officials in Labuhan Haji sub-district, East Lombok Regency. The type of research used is explanatory research. The analysis technique is carried out using multiple linear regression. The results of this research are that simultaneously, the quality of work life, leadership and personality have a significant positive effect on employee engagement among village officials. Meanwhile, partially, quality of work life and leadership have no influence on employee engagement. Meanwhile, personality has a significant positive influence on employee engagement of village officials in Labuhan Haji sub-district, East Lombok district.
ANALISIS KINERJA PEGAWAI SEKRETARIAT DPRD KABUPATEN LOMBOK TIMUR
Authors: Luthfi Abrorni , Mulyono Sugeng , Suswati Endang , Sulaiman Sulaiman
Published: March 2024

The aim of this research is to explore and describe the performance of East Lombok Regency DPRD Secretariat Employees. This research is a type of descriptive quantitative research. The population in this study was 79 East Lombok Regency DPRD secretariat employees consisting of 40 people with ASN status and 39 people with honorary staff status. The number of samples in this study was 64 in accordance with the number of questionnaires returned. The data analysis technique used in this research is the percentage technique. The research results show that; Performance Analysis of East Lombok Regency DPRD Secretariat Employees based on indicators of productivity, service quality, responsiveness and accountability falls into the "Good" category at 74.5%.
Transcending: The journey and lived experiences of the educators who survived COVID-19
Authors: Jaziel Naomi Corpuz-Reyes  , Erlinda Cruz-Mones
Published: March 2024

This study described how the educators, both from public and private schools in Cabanatuan City, managed and survived the difficulties they experienced while battling the Covid-19 virus. The researcher used a descriptive phenomenological design for this study, of which an in-depth interview was conducted to generate qualitative data from the twelve (12) educators from public and private schools in Cabanatuan City. Thematic analysis was applied in emerging the five (5) themes, namely: (1) The Crossover of COVID-19 (Initial reaction of participants when infected), (2) Pyschosocial Distress Behind the Wall (Physical, Psychological, Social Difficulties including the Post Covid-Symptoms), (3) Conquering Adversaries (Coping Mechanism applied to survive Covid-19 infection) (4) Transcending Life’s Meaning (Life lessons learned from their Covid-19 Journey) and (5) Proposed Policy for Educational Institutions (Policies suggested based on their experiences). The findings of the study showed that: the phenomenon under study showed the educators’ resiliency through their faith and positivity, which enabled them to survive the difficulties they faced as Covid-19 patients. All these themes form a central idea that educators are in need of institutional support when faced with a health crisis, such as the pandemic, that can put their lives at risk. Based on the results, the researcher crafted a proposed institutional policy that will aid and support the employees in times of health crisis.
Representações femininas em diferentes versões da peça “Anfitrião” no Brasil Colônia e sua relação com a historiografia de Ronaldo Vainfas
Authors: Artuso Alysson Ramos
Published: March 2024

O artigo realiza uma análise comparativa das representações da mulher em diferentes versões da peça “Anfitrião”, de Plauto, em especial nas versões de Camões e Antônio José da Silva na época do Brasil Colônia. Trata-se de uma comédia sobre o mito de nascimento de Hércules, mas que se desenrola em torno de temas como relações de poder, violência, estupro e adultério. O estudo explora as nuances das personagens femininas, suas interações com os elementos sociais e históricos das respectivas épocas de escrita de peças e como essas representações dialogam com as pesquisas de Ronaldo Vainfas sobre a posição da mulher na sociedade colonial brasileira. As diferenças entre as versões da peça são examinadas em relação à visão social da mulher, da traição, da punição e de formas de resistência feminina. Por fim, o trabalho busca contribuir para um entendimento mais abrangente das mudanças culturais e sociais ao longo dos séculos, através da lente da literatura e de suas interações com a realidade histórica.
Acute disseminated encephalomyelitis as an emergency
Authors: Yevtushenko S. K. , Sorokin Yu. N.
Published: March 2024

Acute disseminated encephalomyelitis (ADEM) is a common acute multifocal autoimmune infl ammatory demyelinating disease of the central nervous system (CNS) with a predominant lesion of the white matter of the brain, brainstem and optic nerves, the conductors of the spinal cord, less often — gray matter of the CNS. ADEM is usually a self-limiting condition with spontaneous improvement and a favorable prognosis. Along with the possibility of a severe course in the classical form of ADEM, the development of hyperacute forms with a much more unfavorable prognosis is possible. Such variants of the course of ADEM are acute hemorrhagic leukoencephalitis (AHLE), acute hemorrhagic leukoencephalomyelitis and acute necrotizing hemorrhagic leukoencephalitis of Hurst, associated with the development of a cascade of hyperacute uncontrolled autoimmune reactions. The severity of these conditions (grouped under the term OHLE) is associated with rapid progression, brainstem involvement, large lesions is due to the development of acute edematous necrosis and hemorrhage with a high possibility of disability or death. The aggressive and severe course of АHLE requires the immediate initiation of decongestant and immunosuppressive therapy.
Epidemiological characteristics of multiple sclerosis in Stavropol region
Authors: Larin G. V. , Larina E. M. , Raevskaya A. I. , Vyshlova I. A. , Karpov S. M.
Published: March 2024

Multiple sclerosis (MS) is a chronic autoimmune, infl ammatory and degenerative disease of the central nervous system and is the most common neurological disorder in young people.

Purpose: to determine the clinical and epidemiological features of multiple sclerosis usig the example of the Stavropol region (SR).

Materials and methods. A retrospective analysis of 655 medical records of patients for 2021–2022, hospitalized in the neurological department of a multidisciplinary hospital with a diagnosis of MS, was carried out. The age, gender, place of residence of the patient, age of onset of the disease, type of MS, degree of disability, and rate of disease progression were assessed. Statistical processing was carried out using Microsoft Excel and Statistica 10 software.

Results. The incidence of MS during this period was 22.7 per 100,000 population. The share of women was 70.2%, men — 29.8%. Average age — 40.04 ± 10.8 years. The vast majority of cases of onset of MS (83.2%) occur between the ages of 21 and 50 years — 82.8% of women and 84% of men. When analyzing the severity of neurological defi cit, the average score on the extended Kurtzke scale of disability was 3.53 ± 1.7 points. The rate of progression was 1.21 ± 1.1 points per year, which corresponds to a fast pace. Among those hospitalized, 65.4% have a disability group: third — 41.9% (275 patients), second — 21.4% (140 patients), fi rst — 2.1% (14 patients).

Conclusion. The Stavropol Territory is one of the regions with a moderate risk of developing multiple sclerosis. The results of the work may be useful in planning medical and social care in certain territories of this region.
Sistem Informasi Praktek Kerja Lapangan Jurusan TI Prodi Manajemen Informatika
Authors: Roni Putra  , Adi Atma Yori , Firosha Ardian , Sumema  , Mustika Zalna
Published: March 2024

Setelah melakukan uji implementasi untuk melihat respon penggunaan dari sistem maka di buatlah kuesioner, total data yang terkumpul sebanyak 55 responden  dari mahasiswa program studi manajemen informatika angkatan 2020, sebanyak 26,75% menjawab Baik Sekali, 58,44% menjawab Baik, 13,51% menjawab Cukup dan 1,30% menjawab Kurang. Dari hasil kuesioner dapat di simpulkan persentase paling tinggi adalah Baik sehingga sistem informasi pengusulan PKL layak untuk di gunakan.  Untuk kendala teknis dan gangguan dari penggunaan sistem 0,15% menjawab tidak pernah, 30,91% menjawab jarang, 49,09% menjawab kadang-kadang dan 5,45% menjawab sering, dari persentase tersebut bisa di simpulkan jarang terjadi kendala teknis atau error saat aplikasi di gunakan
Pengaruh Program Keluarga Harapan Terhadap Tingkat Kesejahteraan Keluarga Berdasarkan Perspektif Ekonomi Islam
Authors: Soraya Elvira Tami , Amir Amri , Lubis Paulina
Published: March 2024

Tujuan –Tulisan ini membahas mengenai pengaruh program keluarga harapan (PKH) terhadap tingkat kesejahteraan keluarga penerima manfaat dari sudut pandang ekonomi islam di Kota Jambi.
Metode – Pendekatan yang digunakan dalam penelitian ini adalah metode kuantitatif dengan menggunakan metode analisa data berupa uji validitas, uji reliabilitas dan regresi linear sederhana.
Hasil – Hasil penelitian menunjukkan bahwa Program Keluarga Harapan (PKH) berpengaruh Positif dan signifikan terhadap tingkat kesejahteraan Keluarga penerima bantuan PKH.
Originalitas – Penelitian ini mengungkap pengaruh program keluarga harapan terhadap tingkat kesejahteraan penerima manfaat perspektif ekonomi islam di kota Jambi.
Implikasi – Program keluarga harapan sangat membantu keluarga kurang mampu dalam meningkatkan kesejahteraan keluarga dan juga menjaga stabilitas kehidupan mereka terhadap kebutuhan pokok dan krisis ekonomi yang melanda masyarakat kurang mampu.
Pengaruh Pembiayaan Mudharabah Dan Pembiayaan Musyarakah Terhadap Profitabilitas (Studi Pada Bank Umum Syariah Pada Priode 2016-2020)
Authors: Cintia Ardilla , Syahpawi Syahpawi , Nurnasrina Nurnasrina
Published: March 2024

Tujuan – Penelitianl ini bertujuanl untukl (1) mengetahuil bagaimana pembiayaan mudharabahl berpengaruh terhadap profitabilitasl (ROE) padal Bank Umuml Syariahl periodel 2016-2020 (2) mengetahuil bagaimana pembiayaanl musyarakah berpengaruh terhadapl profitabilitas (ROE) padal Bank Umuml Syariah periodel 2016-2020 (3) mengetahuil bagaimana pembiayaanl mudharabah danl pembiayaan musyarakahl berpengaruh secara simultanl terhadap profitabilitas (ROEl) pada Bankl Umum Syariahl periodel 2016-l2020.
Metode – Jenisl penelitianl ini adalahl penelitian lkuantitatif. Penelitian ilmiahl yangl sistematisl terhadap lbagian-bagian danl fenomena sertal hubungan lantar-bagian danl fenomena tersebutl
Hasil – Daril hasil analisisl yang telahl dilakukan makal dapat ditarikl kesimpulan bahwal pembiayaan mudharabahl tidak berpengaruh secaral negatif dan tidak signifikan terhadapl Returnl Onl Equity. Pembiayaanl musyarakah ltidak berengaruh secara negatif dan tidak signifikanl terhadap Returnl On lEquity. Pembiayaan mudharabahl danl pembiayaan musyarakahl secara simultanl berpegaruh signifikanl terhadap Returnl On Equity.
Originalitas - Penelitianl ini difokuskan pada pembiayaan mudharabah dan musyarakah, menghadirkan pemahaman yang mendalam tentang dampak keduanya terhadapl Return Onl Equity (lROE) dalam konteks perbankan syariah.
Implikasi – Penelitianl ini dapatl memberikan wawasan bagi bank syariah di negara-negara lain untuk mengevaluasi strategi pembiayaan dan memperkuat praktik-praktik yang dapat meningkatkan profitabilitas dengan mempertimbangkan kombinasi pembiayaan mudharabah dan musyarakah.
Pengaruh Religiusitas Terhadap Minat Masyarakat Menggunakan Produk Perbankan Syariah di Kota Pekanbaru
Authors: Usnan Usnan
Published: March 2024

Tujuan - Penelitian ini bertujuan untuk mengetahui pengaruh religiusitas terhadap minat masyarakat menggunakan produk Bank Syariah di kota Bandar Pekanbaru.

Metode – Penelitian ini menggunakan teknik purposive sampling dalam menentukan sampel dan diperoleh sampel 100. Pengujian instrumen dilakukan dalam peneliitan ini, setelah itu peneliti menggunakan metode regresi linier sederhana untuk menguji hipotesis penelitian.

Hasil – Hasil penelitian menunjukkan bahwa variabel religiusitas dapat mempengaruhi minat masyarakat menggunakan produk bank syariah sebesar 20,3%. Dengan hasil analisis yang menunjukkan bahwa variabel religiusitas memiliki nilai signifikansi 0,000 yang berarti variabel religiusitas memiliki pengaruh positif dan signifikan terhadap minat masyarakat menggunakan produk bank syariah.

Originalitas (Novelty) -  Penelitian ini berusaha mengungkap pengaruh religiusitas yang dimiliki oleh nasabah terhadap minat dalam menggunakan produk perbankan syariah.

Implikasi – Hasil ini memberikan peluang kepada Bank Syariah Mandiri untuk meningkatkan sosialisasi produk bank syariah kepada masyarkat. Karena, semakin meningkatnya religiusitas maka kecenderungan masyarakat berminat untuk menggunakan produk bank syariah semakin meningkat.
Studi Literatur: Penilaian Kesehatan Bank Syariah
Authors: Hazwin Hazwin , Nurnasrina Nurnasrina , Syahpawi Syahpawi
Published: March 2024

Tujuan – Tujuan dari Penulisan ini untuk membahas tentang penilaian kesehatan Bank Syariah, Dasar hukum tentang pengaturan penilaian kesehatan Bank Syariah (BUS dan BPRS) merujuk kepada aturan UU, PP, PBI, POJK dan surat edaran BI, OJK dan menjelasakan tentang penilaian RGEC pada Bank Syariah.
Metode – Penulisan ini menggunakan pendekatan kualitatif dengan desain penelitian studi pustaka. Penulisan ini menggunakan jenis literatur review terhadap berbagai sumber bacaan yang berhubungan dengan penilaian kesehatan Bank Syariah, dasar hukum BUS dan BPRS, dan RGEC.
Hasil – Penelitian ini menunjukkan penilaian kinerja bank untuk mengatasi risiko dan memantau kinerjanya, mencerminkan fungsi dan kesehatan bank. Penilaian kesehatan Bank Umum Syariah (BUS) didasarkan pada Undang-Undang Nomor 21 tahun 2008 tentang Perbankan Syariah, yang mewajibkan bank menjaga tingkat kesehatannya sesuai dengan POJK No. 8 tahun 2014. Sementara itu, penilaian kesehatan Bank Perkreditan Rakyat Syariah (BPRS) mengikuti Peraturan Bank Indonesia No. 9/17/PBI/2007. Metode RGEC, pengembangan dari CAMELS, menilai delapan faktor risiko, termasuk kredit, pasar, likuiditas, operasional, hukum, stratejik, kepatuhan, dan reputasi dalam operasional bank.
Originalitas – Penulisan ini mengungkapkan penilaian kesehatan pada bank syariah, dasar hukum Bank Umum Syariah (BUS), Bank Perkereditan Rakyat Syariah (BPRS), dan penjelasan tentang penilaian RGEC (risk profile, governance, earnings and capital).
Implikasi – Bank yang sehat adalah bank yang dapat menjaga dan memelihara kepercayaan masyarakat, dapat berperan sebagai intermediasi, dapat membantu kelancaran arus pembayaran, dan dapat digunakan oleh pemerintah untuk melaksanakan berbagai kebijakan khususnya kebijakan moneter.