bluuebunny/crossref_metadata_2025 huggingface dataset:
Systematic Review: Scoring Triage in Pandemic Covid-19
Authors: Octaviani Dinda Sesylia , Kamaluddin Ridlwan
Published: December 2022

Background: Patients with emergency conditions will get the first health service in the Emergency Room (IGD). The emergency room nurse has an important role in assessing and determining the severity of the patient. The nurse determines the priority of action and the need for treatment in Intensive Care Unit (ICU) using triage. One of the triage that can be done is triage scoring to facilitate nurses in determining high-risk and low-risk patients. Purpose: To find out the triage scoring used during the pandemic. Methods: Literature search is conducted using the PICO framework. This systematic review is limited to articles published from 2019-2021 with articles in English. The database used is Google Scholar. PubMed, Science Direct, and ProQuest which using the keywords score, triage, pandemic and emergency care. Results: Based on the three articles reviewed, an overview of the use of triage scores during a pandemic is obtained using the SODA score, modified PRIEST and double triage and telemedicine protocols. Giving the triage score can make it easier for health workers to identify high-risk patients and prevent unexpected events. Conclusion: Triage scoring can be applied at Covid-19 referral hospitals which helps nurses determine priorities and prevents special mortality in Indonesia, which is experiencing the second wave Keywords: Score, Triage, Pandemic
Literature Review: The Effectiveness of Tabletop Disaster Exercise on Disaster Preparedness
Authors: Darmawan Nur Adi , Kamaluddin Ridlwan
Published: December 2022

Backgrounds: Disasters often come without warning and canresulted in a lot of losses. Preparedness is a form of activity carried out to anticipate disasters. One of the activities that can be done to improve preparedness is by simulating using the Tabletop Disaster Exercise (TDE) media. Therefore, it is important to identify the effectiveness of tabletop disaster exercise on disaster preparedness.Objective : To assess the effectiveness of tabletop disaster exercise on disaster preparedness.Methods: The study was conducted based on the study. The search is limited to articles published in 2017-2021, full text, using the tabletop disaster exercise method with the type of original research. The databases used are Pubmed, National Library of Indonesia, and Google Scholar with the keywords tabletop disaster exercise, disaster, preparedness.Results: Five articles were found on the implementation of TDE which aims to improve preparedness and knowledge of disasters. The article contains knowledge, self-confidence, understanding of the role of disaster preparedness. The results of the analysis carried out on the five articles taken were the effectiveness of the tabltop disaster exercise on disaster preparedness with a value of p = 0.001 or p 0.05.Conclusion: The Tabletop Disaster Exercise is effectively implemented to improve disaster preparedness.Keywords: tabletop disaster exercise, disaster, preparedness
Analisis Indeks Paparan Radiografi Digital Pada Pemeriksaan Radiologi Thoraks Postero Anterior Sebagai Upaya Peningkatan Proteksi Radiasi Pasien
Authors: Samsul Aris
Published: December 2022

ABSTRACT Backgound:  Digital radiography is an easy method of radiological examination, so many radiology technicians often use high exposure factors because they are considered to speed up when processing images, this can increase the risk of excessive radiation doses in patients, currently the exposure index (IE) is feedback to radiology technicians for optimal images and low doses for patients. Objective: evaluating Fujifilm (S-Value) exposure index and entrance surface dose (ESD) thorax posterior-anterior as an effort to increase patient radiation protection using the ALARA principle, Method: Data taken from samples with parameters 64 kVp 16 mAs to 94 kVp 2 mAs, ESD is measured using the thermoluminescent dosimeter (TLD) chip and exposure index (S-Value) from Fujifilm's direct radiography device. Result: The relationship between S-Value and ESD has an exponential trend graph. The rise of S-Value will be followed by the ESD sequence. With the BAPETEN reference value of surface radiation dose 0.40 mGy, the minimum S-value must be achieved so that the patient's ESD does not exceed S-532 at ESD 0.39. Conclusion: The results of this study indicate that Fujifilm's S-Value allows it to be used as an evaluation of the ESD values received by patients as an effort to increase patient radiation protection. Keywords:  Exposure index (S-Value), ESD, chest radiography, radiation protection
Violence Against Black Women in Politics: Experiences and Testimonials from Brazil
Authors: de Souza Lima Lívia , Fabris Ligia , Goulart da Silva Mayra
Published: December 2022

In this article the authors aim to understand the specificity of violence against Black women in Brazilian politics through the analysis of testimonies of Black politicians in different administrative positions and various regions of Brazil. Adopting the “Violence Against Women in Politics” (VAWIP) analytical model developed by Mona Lena Krook, the goal of this approach is to highlight the forms that this violence takes in the Brazilian context when gender and race intersect. In doing so, the article pursues two objectives. First, it offers an overview of violence against Black women in Brazilian politics, demonstrating how this phenomenon manifests itself in the analysis of these cases. Second, it observes how the testimonies of Black women politicians go beyond the analytical model proposed by Mona Lena Krook (2020), thus accounting for the intersectional specificities of political violence.
EFEKTIVITAS PERLAKUAN AWAL ALKALI DAN HIDROTERMAL TERHADAP PROSES DELIGNIFIKASI, POTENSI GULA REDUKSI DAN PRODUKSI ETANOL TEORITIS DARI KAYU Vernonia amygdalina Delile
Authors: Ufa Mardiatul , N Nasriati , Ningrum Aulia Fitria , Suwinarti Wiwin , Amirta Rudianto
Published: December 2022

Vernonia amygdalina merupakan salah satu jenis tanaman Short Rotation Coppice (SRC) atau trubusan yang secara alami dapat melakukan proses regenerasi setelah melalui proses pemangkasan. Selain itu juga sebagai bahan baku penyedia biomassa yang saat ini banyak digunakan dalam memproduksi energi di dunia. Oleh karena itu, V. amygdalina memiliki potensi pembangkitan energi yang besar dan memadai untuk digunakan salah satunya adalah sebagai bahan baku untuk produksi bioetanol. Penelitian ini bertujuan untuk mengetahui efektivitas perlakuan awal yang dilakukan dengan menggunakan konsentrasi alkali dan waktu reaksi yang berbeda terhadap proses sakarifikasi dan gula tereduksi yang dihasilkan beserta potensi teoritis dari etanol yang diperoleh. Biomassa kayu terlebih dahulu diolah dengan autoklaf pada berbagai konsentrasi NaOH (0, 1, 2, dan 3% (g/L)) dan waktu reaksi (15, 30, 45, dan 60 menit). Sampel kayu yang telah diolah kemudian dihidrolisis menggunakan enzim selulase komersial untuk menghasilkan monomer glukosa. Waktu hidrolisis pada 12, 24, 36, dan 48 jam dianalisis. Hasil penelitian menunjukkan bahwa penambahan NaOH 3% pada waktu reaksi 15 menit dan waktu hidrolisis 36 jam merupakan konsentrasi terbaik untuk memberikan potensi etanol tertinggi (186,98 L/ton biomassa kayu). Akhirnya, penelitian ini menunjukkan bahwa V. amygdalina akan menjadi bahan baku yang menjanjikan untuk produksi etanol.
Kovács Tamás: A Honvédelmi Minisztérium „T” szervének létrejötte és működése
Authors: Lippai Zsolt
Published: December 2022

Könyvismertetés. Kovács Tamás: A Honvédelmi Minisztérium „T” szervének létrejötte és működése. Avagy elhárítás és kémkedés az I. világháború végétől a bethleni konszolidációig. Nemzeti Közszolgálati Egyetem, Közigazgatási Továbbképzési Intézet, 2020
Gondolatok a magyar helyreállító igazságszolgáltatásban rejlő lehetőségekről
Authors: Czenczer Orsolya , Hollósvölgyi Máté
Published: December 2022

A resztoratív igazságszolgáltatásban Magyarországon számos szakembercsoport érintett: pártfogó felügyelők, rendőrök, ügyvédek, büntető bírák, ügyészek, szociális munkások, pedagógusok. Mindezek mellett ott vannak a potenciális elkövetők és közösségeik. Hogy hogyan lehetséges ennyi érintett egyesítése interdiszciplináris módon, egy közös cél érdekében, hogyan lehetséges a konfliktusokat a közösségi kötelékek erősítésére használni, és remélhető-e igazság azáltal, hogy a sérelem okozására adott válasz célja a sérelem helyreállítása, mind-mind olyan kérdések, amelyek mentén meg lehet ismerni a büntető igazságszolgáltatás egyik legmodernebb elemét: a helyreállító igazságszolgáltatást. Jelen tanulmány célja górcső alá venni a hazai mediációs eljárások rendszerszintű működését a Pártfogó Felügyelői Szolgálat mediátorain keresztül. A büntetőügyekben alkalmazható mediáció Magyarországon 2007. január 1. óta vált országosan elérhető szolgáltatássá. Ettől a naptól kezdve a pártfogó felügyelők munkája kiegészült mediátori teendőkkel is. Jelen tanulmány keretében áttekintjük a mediációs eljárásokkal kapcsolatos pártfogói feladatokat, azok hatékonyságát és reintegrálhatóságát a teljes büntető igazságszolgáltatási folyamatba.
Acidentes por animais peçonhentos no Estado do Paraná, Brasil
Authors: Navarro Júlia Garbin , Uchida Denise Tiemi , Machinski Jr Miguel
Published: December 2022

Acidentes por animais peçonhentos são considerados uma questão de saúde pública, entretanto, poucos estudos retratam a realidade deste problema no Paraná. Assim, este trabalho objetivou analisar o perfil epidemiológico deste agravo no estado. Foi realizado um estudo observacional ecológico, utilizando dados de 2010-2019 fornecidos pelo Sistema de Informação de Agravos de Notificação. Observou-se uma tendência crescente dos acidentes, sendo a maioria ocasionado por aranhas, contudo, houve um aumento daqueles provocados por escorpiões e abelhas. O gênero masculino foi o mais afetado e as vítimas majoritariamente receberam atendimento na primeira hora após a picada. A taxa de letalidade foi de 0,07%, e as abelhas causaram o maior índice de óbitos. Dos 399 municípios paranaenses, 137 apresentaram taxas de incidência com valores significativos (p<0,05), e desses, 48 formaram clusters do tipo High-High. Salienta-se a necessidade de implementação de medidas estratégicas para o combate ao agravo, especialmente nos municípios clusters High-High.
Branding strategies in transitional economy: The case of Aimer
Authors: Yu Hong , Rahman Osmud , Yan Yi
Published: December 2022

The purpose of the study was to investigate the branding strategies implemented by the Beijing Aimer Lingerie Company Ltd. that support its success. A case study method was used which included on-site visits and in-depth interviews with Aimer executives, mid-level managers, and frontline employees. Additionally, a review of the company’s website and internal documents, as well as an extensive external search of relevant news reports, social media contents, industry information, and academic literature contributed to the data source. The study adopted a deductive content analysis strategy by integrating Balmer and Gray’s (2003) C2ITE framework and the luxury fashion brand dimensions, and used triangulation as a validation strategy. The most important element of Aimer’s success is strategic planning and continuous brand development. In every step of Aimer’s business development, the executive team strategically planned its next step and had a clear vision for the future. Aimer executed well for each dimension of the analytical framework (Cultural, Marketing Communication, Tangible Branding, Intangible Branding, and Commitment) except one: brand signature (Cultural dimension). The findings provide valuable implications for other Chinese apparel manufacturers striving to establish their own brands, as well as global companies that compete in the Chinese marketplace.
A study of Canadian female baby boomers: Physiological and psychological needs, clothing choice and shopping motives
Authors: Rahman Osmud , Yu Hong
Published: December 2022

The purpose of this paper is to gain an understanding of baby boomers’ physiological and psychological needs through clothing consumption.

This study intended to offer new knowledge on the issues of baby boomers’ unmet needs, and provide insights and implications to fashion practitioners. A qualitative research approach was employed for this study. Data were collected from two generational segments: early baby boomers (1946–1954), and late baby boomers (1955–1964). In total, 13 informants aged from 53 to 71 years were participated in this study. Content analysis and interpretive approach were used for data analysis. According to the findings, there are several reasons why the baby boomers shopped for clothing, including a way of stress relief or retail therapy, wardrobe update, replacement of worn-out garments, attractiveness of clothing styles and convenience. Style, fit, comfort and colour were the four most important product evaluative cues. Other than product cues, age appropriateness is an important factor for clothing consumption. Many informants were disappointed with their current body type, shopping experience and the industry offers. Age-appropriate clothing can give wearers greater self-assurance/-gratification. If fashion designers create their products based on the baby boomers’ cognitive age, it would probably increase their customers’ acceptance and satisfaction. The rapid growth of the aging population is a global phenomenon. Therefore, investigating the needs and challenges of the baby boomer generation is both timely and imperative. 
Fashion Innovativeness in India: shopping behaviour, clothing evaluation and fashion information sources
Authors: Rahman Osmud , Kharb Devender
Published: December 2022

There are limited empirical studies that have focused on apparel consumers in India, and none of the previous research has explicitly examined the relationship between fashion innovativeness, consumers’ shopping behaviour, product evaluative cues and fashion information sources. This study is intended to address this research gap. A self-administered survey was used for this study. In total, usable data were collected from 230 female participants aged from 18 to 25 years in New Delhi, India. The results indicated that fashion innovators spent more money on new clothes and shopped more frequently online/offline per year than did fashion non-innovators. Garment fit and comfort were perceived as the two most significant cues for both consumer groups. Fashion innovators relied more often on impersonal or marketer-dominated sources – for fashion information including magazines, store/window displays and celebrities, while fashion non-innovators were more reliant on personal or non-marketer-dominated sources including parents, friends and siblings.
Exploring the implementation and delivery of primary care services for transgender individuals in Ontario: case study protocol
Authors: Ziegler Erin , Valaitis Ruta , Carter Nancy , Risdon Cathy , Yost Jennifer
Published: December 2022

Background: Historically transgender adults have experienced barriers in accessing primary care services. In Ontario, Canada, health care for transgender adults is accessed through primary care; however, a limited number of practitioners provide care, and patients are often waiting and/or traveling great distances to receive care. The purpose of this protocol is to understand how primary care is implemented and delivered for transgender adults. The paper presents how the case study method can be applied to explore implementation of health services delivery for the transgender population in primary care. Methods: Case study methodology will be used to explore this phenomenon in different primary care contexts. Normalization Process Theory is used as a guide. Three cases known to provide transgender primary care and represent different Ontario primary care models have been identified. Comparing transgender care implementation and delivery across different models is vital to understanding how care provision to this population can be supported. Qualitative interviews will be conducted. Participants will also complete the NoMAD (NOrmalization MeAsure Development) survey, a tool measuring implementation processes. The tool will be modified to explore the implementation of primary care services for transgender individuals. Documentary evidence will be collected. Cross-case synthesis will be completed to compare the cases. Discussion: Findings will provide an Ontario perspective on the implementation and delivery of primary care for transgender adults in different primary care models. Results may be applicable to other primary care settings in Canada and other nations with similar systems. Barriers and facilitators in delivery and implementation will be identified. Providing an understanding and increasing awareness of the implementation and delivery of primary care may help to reduce the invisibility and disparities transgender individuals experience when accessing primary care services. Understanding delivery of care could allow care providers to implement primary care services for transgender individuals, improving access to health care for this vulnerable population.

 
The Aesthetics of Images and Language between Defeat and Creativity in Al-Khansa’s Lament: Analytical Study of “A Moda in Your Eyes” Poem
Authors: Al Banna Hermin Samir Mustafa
Published: December 2022

The research aims to study the manifestations of psychological defeat and the aesthetics of images and language in Al-Khansa’s poetry, an analytical psychological reading, and it influenced Al-Khansa’s poetry, because it was characterized by the sincerity of feelings and emotional feelings. Sadness, crying, pain and suffering in her poetry, and the follower of Al-Khansa’s poetry in lamentation finds the echo of psychological defeat in her poems as a result of the loss of her brother and her bereavement in him. Al-Khansa’s poetry, especially lamentation, prompts the reader to represent the state of refraction and pity that he sees in the poetic images, the chosen language, and the glimpse of sadness that dominates the music of her poems.We stand on Al-Khansa’s poetry as a poet capable of her artistic tools on the one hand, and the weak female woman who has nothing but moans and groans and her body on the other hand to express her sadness, to reveal the subconscious side using the psychoanalytic mechanisms of the poems of lamentation and show the pent-up psychological struggles as a result of psychological and dark labyrinths that she faced with death her brother.The events begin with the broken, painful female Khansa, to unveil the effect of the psychological defeat that she went through, so she transformed her life and tried to resist it with all her strength to face the multiple psychological disorders, some of which are about to turn into a decade.Then the research aims to clarify the impact of manifestations of psychological defeat on the aesthetics of the poetic elegiac images of Khansa, to monitor its implications, and the dimensions of this effect on the elegy of Khansa in the light of psychoanalytic reading, in order to clarify the poetic image and probe the depths of the aesthetic impact and artistic formulation and for the recipient. Especially lamentation is just a feeling or a fleeting state, but it was a position and an entity, and we have summarized the reading of lamentation in conjunction with the psychological dimension, to seek the emotions of the recipient as a result of his sense of Khansa’s special vision and her psychological state.
Wenn sich eine Frau in der Männerdomäne durchsetzt – Magdalena Heymair und ihre Publikationsaktivitäten
Authors: Lichnerová Lucia
Published: December 2022

Der Artikel widmet die Aufmerksamkeit der Schriftstellerin, Autorin evangelischer Liederbücher, Pädagogin und Lehrerin des 16. Jahrhunderts, Magdalena Heymair, die ursprünglich aus Deutschland stammte, durch die Lebensumstände aber gezwungen war, in mehreren Orten Deutschlands, Österreichs und schließlich der Slowakei zu wirken. Zu Beginn des Artikels charakterisiert die Autorin kurz die Position der Frau im 16. Jahrhundert, die nach und nach männliche Stereotype überwand, wodurch es auch Frauen möglich war, sich in verschiedenen Berufen durchzusetzen. Der Artikel zeichnet das Bild einer Frau, die sich nicht nur in den Männerberufen durchsetzen konnte, sondern die durch ihre schriftstellerische Tätigkeit eine wichtige Frauenrolle im Reformprozess bewies. Darüber hinaus konzentriert sich die Autorin auf das Leben und insbesondere das Wirken und den Beitrag M. Heymairs zur Entwicklung des evangelischen Religionsunterrichts und skizziert den Zeitrahmen von der Schöpfung der Manuskripte bis zu ihren gedruckten Ausgaben und Nachdrucken in mehreren Städten und Verlagen Europas.
Cor castum Dei speculum: Emblematics and the Heart Emblem in Jesuit Literature
Authors: Špániová Marta
Published: December 2022

This study focuses on the characteristic features of the emblems, the emblematic procedure, and the main functions, goals, and significance of the emblem books in the context of Jesuit spirituality and practice. It points out some prominent authors of Jesuit emblem books with a major influence on the development of this form of art in literature and art. It focuses on the heart emblem as a symbol of heart purification and on the artistic manifestations of “religio cordis” (the religious cult of the heart). It introduces one of the most popular books with heart emblems published on the territory of present-day Slovakia in the first half of the seventeenth century, the so-called “heart booklet” of Mátyás Hajnal, a typical sample of Jesuit emblematics devoted to the promotion of Catholic reforms at the time of the Counter-Reformation.
Object Classification and Tracking Using Scaled P8 YOLOv4 Lite Model
Authors: Shaikh Shakil , Chopade Jayant , Kharate Gajanan
Published: December 2022

One of the most difficult tasks in the area of computer vision is object detection, which combines object categorization and object location within a scene. In terms of object detection, Deep Neural Networks have been recently demonstrated to outperform alterna-tive approaches. The issues related deep learning neural network is its complexity and huge computation, so it is not possible to detect and track the objects in image of high resolution in real time. We proposed scaled YOLOv4 lite model as Single Stage Detector Neural Network for object detection, tracking and it is trained using COCO 2017 dataset. To create the YOLOv4-CSP- P5- P6- P7- P8 networks, the Scaled YOLOv4 applied efficient network scaling strategies. The additional layer in YOLOv4 lite model is added as P8 layer which improves accuracy. Cross-stage-partial (CSP) connections and Mish activation are used in improved network design, such as backbone optimization and Neck (PAN). In the case of YOLOv4, however, it can only be trained once for all resolutions. Width and Height activations have been changed, allowing for faster network training. With YOLOv4 lite model, we used CSPDarkNet-53 model as a backbone. The experimental result show our YOLOv4 lite model can detect and track object up to 28 fps when model run with the video input and has an accuracy of 86.09% when tested on real-time video with resolutions 1920 × 1080 (full HD). AP = 50.81%, AP @50 = 63.6%, and AP @75 = 52.5% for CSPDarkNet-53 model backbone.
Rancang Bangun Aplikasi Kasir Penjualan pada Usaha Mikro Kecil Mengengah 3Manstore Berbasis Web
Authors: Mulyani Asri , Setiawan Ridwan , Rusmana Ruli Ahmad
Published: December 2022

Aplikasi kasir penjualan pada usaha mikro kecil menengah merupakan jawaban terhadap permasalahan yang ada pada salah satu usaha mikro kecil menengah pengrajin tas yang berada di daerah Leles Kabupaten Garut. Hasil dari observasi dan wawancara dengan pemilik usaha mikro kecil menengah permasalahan yang ada adalah proses transaksi masih manual menggunakan nota tulis sehingga sangat riskan untuk nota hilang atau rusak, proses perhitungan laba yang kadang tidak balance dikarenakan human error saat proses rekapitulasi serta tidak adanya catatan hutang sehingga saat proses pembayaran hutang reseller kadang tidak sinkron. Tujuan dibuatnya aplikasi ini adalah untuk membantu proses kegiatan penjualan pada usaha mikro kecil menengah, membantu mengelola hutang piutang, dan membantu proses rekapitulasi laporan laba rugi. Rational Unified Process (RUP) yang di mana tahapan pelaksanaannya hanya meliputi inception, elaboration, dan construction menjadi bagian dari metodologi yang digunakan. Kemudian mengguinakani pemodnelan Uinifbieid Miodeilling Lainguaige dan penigujian alpha dengan menggunaiikan metoidie Blacik Box Tiesiting dilakukan pada tahapan construction, sedaingkan uintuk bahiasaipemiograman ialah PHP dan MiySql sebiagai basis datanya. Hasil dari peneliatian ini berupa Aplikasi Kasir Penjualan Untuk Usaha Mikro Kecil Menengah Berbasis Web yang memilih hak akses multi-user serta sudah dilengkapi dengan fitur transaksi, manajemen hutang dan  laporan laba rugi.
Analisis Penerimaan Sistem Informasi Akademik Mahasiswa (SIAM) Institut Teknologi Garut Menggunakan Metode Technology Acceptance Model
Authors: Mulyani Asri , Nashrulloh Muhammad Rikza , Karlina Ai
Published: December 2022

Institut Teknologi Garut menerapkan sistem informasi akademik bagi mahasiswa sebagai institusi pendidikan. Ketika sebuah institusi menerapkan sistem informasi, penerimaan pengguna harus dipertimbangkan. Tidak pernah ada evaluasi penerimaan pengguna sistem sejak diterapkan. Penelitian ini menguji penerimaan siswa terhadap pengguna sistem dengan menggunakan Metode Technology Acceptance Model. Data evaluasi, kuesioner dikirim ke mahasiswa aktif Institut Teknologi Garut, dengan total 1.681 responden dan ukuran sampel 200. Hasil yang didukung hanya dua dari lima hipotesis yang diuji dalam penelitian ini. Salah satunya adalah bahwa Organisasi E-Resources berpengaruh positif terhadap Perceived of Ease of Use, dengan nilai probabilitas 0,000 atau kurang dari 0,05 yang menunjukkan bahwa pengaruh tersebut signifikan pada taraf signifikansi 5%. Organisasi E-Resources tidak berpengaruh terhadap Perceived of Ease of Use dengan nilai probabilitas 0,077 atau lebih besar dari 0,05 menunjukkan tidak signifikan pada taraf signifikansi 5%, Persepsi Kemudahan Penggunaan tidak berpengaruh terhadap Persepsi Kegunaan dengan nilai probabilitas 0 0,437 atau lebih besar dari 0,05, dan Perceived of Ease of Use tidak berpengaruh terhadap Attitude of Use dengan nilai probabilitas 0,385 atau lebih besar dari 0,05.
Analisis Metode C5.0 Untuk Penyediaan Lapangan Pekerjaan Di Kelurahan Sidorejo Hilir
Authors: Leman Dedi , Maulia Rahman  , Muhammad Hari Ramadhan
Published: December 2022

Masalah pengangguran dan ketenagakerjaan sampai saat ini masih menjadi masalah utama bagi negara-negara berkembang saat ini. Kedua masalah ini merupakan satu kesatuan yang keduanya menciptakan masalah dualisme permasalahan yang saling bertentangan antar satu dengan yang lainnya. Hal ini terjadi jika pemerintah tidak dapat memanfaatkan dan meminimalkan dampak yang nantinya akan ditimbulkan dari permasalahan tersebut dengan baik. namun jika pemerintah mampu memanfaatkan tenaga kerja dengan baik maka ini akan memeberikan dampak positif bagi pembangunan perekonomian negara. Demikian sebaliknya jika pemerintah tidak mampu memnfaatkan maka akan menjadi dampak negative bagi pertumbuhan perekonomian negara. Medan merupakan salah satu kota di provinsi Sumatera utara yang memiliki banyak permasalahan, salah satunya adalah pengangguran. pengangguran bedasarkan factor yang mempengaruhi terjadinya pengangguran maka dibutuhkan metode data mining khususnya algoritma C5.0 Analisis algoritma C5.0 merupakan salah satu solusi pemecahan kasus yang sering digunakan dalam pemecahan masalah pada teknik klasifikasi. Keluaran dari algoritma C5.0 itu berupa sebuah decision tree layaknya teknik klasifikasi lain.
Development of Besifloxacin HCL Loaded Ocular İn Situ Gels; In Vitro Characterization Study
Authors: POLAT Heybet Kerem , ÜNAL Sedat
Published: December 2022

Objective: The aim of this study is to develop in situ gel formulations containing besifloxacin hydrochloride are heat triggered, which are prepared by using different poloxomer and derivatives different polymers that will change the gelling temperature to increase corneal contact time, regulate drug release, improve ocular bioavailability and increase patient compliance increase mucoadhesion.
Material and Method: Various concentrations of poloxamer 188 (P188) and poloxamer 407 (P407) were used to create the in situ forming gels. To increase the gel's capacity for bioadhesion, mucoadhesives such hydroxypropylmethyl cellulose (HPMC) or hydroxyethyl cellulose (HEC) were included in the formulations. Drug release in vitro, sol-gel transition temperature, rheological behavior, pH, clarity, and mucoadhesion force were all assessed for the produced formulations.
Result and Discussion: The developed formulations' gelation temperatures ranged from 29 to 35°C. The preparations' viscosity and mucoadhesion force increased with increasing P407, HPMC, and HEC concentrations. Besifloxacin HCl forms in situ gel formulas with K1, K2, K3, and K6 suited for mucoadhesion characteristics, gelation temperature, and viscosity. These formulations exhibit pseudoplastic flow. Increasing polymer concentrations resulted in a reduction in the burst release of the formulations. However, at the end of 6 hours, drug release was finished in all formulations. The results show that in situ gels containing P407 and P188 show promise for besifloxacin HCl application
Protecting Heart, Vessels, and Bone: New Ways to Control Phosphorus
Authors: Alieva Kabira
Published: December 2022

Prof Alexander Rosenkranz and Prof Markus Ketteler welcomed the audience and the expert panel of the symposium, and briefly described the programme of the meeting. Prof Laurent Juillard discussed the challenges faced in achieving phosphate control in patients on haemodialysis, as well as aspects for optimising the management of hyperphosphataemia. Prof Philip Kalra described recent advances in hyperphosphataemia treatment, concentrating on an iron-based, calcium-free phosphate binder that may offer a lower pill burden compared with previous treatments, and thereby address the challenge of patient non-adherence.
Seizures in Childhood: Aetiology, Diagnosis, Treatment, and What the Future May Hold
Authors: Rubenstein Sara , Levy Andrew
Published: December 2022

Seizures are one of the most common medical problems affecting children, and epilepsy is the most common chronic neurological condition in children. Childhood epilepsy syndromes include a wide spectrum of disorders ranging from benign to life threatening. While there are many known epilepsy syndromes, there are many factors, which may lead to the development of seizures in children including infection, traumatic brain injury, or structural abnormality.

Up to 40% of childhood epilepsies are thought to have some component of genetic involvement. New genes, mutations, and variants involved in epilepsy are being identified continuously. Most of the genes which have been identified encode for neurotransmitter receptors, ion channels, molecules involved in intracellular signalling, or proteins involved in synaptic structure. As new candidate genes in epilepsy are identified, new technologies in genetic testing are becoming available and more accessible, making the molecular diagnosis of epilepsy increasingly relevant to researchers, physicians, patients, and their families.

The standard of care and first-line treatment is the use of antiepileptic drugs. For those patients with medication-refractory epilepsy other available therapies include ketogenic diet, vagal nerve stimulator, or epilepsy surgery. The newest advancement in the treatment of paediatric epilepsies is based around the idea of targeted therapy. These therapies incorporate pharmacogenomics, the principle that an individual’s genetic background affects their response to specific drugs, as well as precision medicine, which identifies treatments for the damaged products resulting from specific gene mutations. Many of these therapies are still under research or in trial; however, there is much promise for the future of targeted medications.
The Normativity of Law in Nature Revisited: Natural Law in Late Hellenistic Thought
Authors: Brouwer René
Published: December 2022

In this paper I revisit nature as a source of normativity for law in the later Hellenistic period, that is beyond the opposition of law and nature in the early classical period, Plato’s and Aristotle’s naturalism, or the early Stoics’ conception of the common law. I will focus on the first century BCE, when the expression ‘natural law’ gained prominence, reconstructing its origins in the interaction between Hellenistic philosophers and the Roman elite, including jurists. I argue that for the jurists the Stoic doctrine of law in nature offered a theoretical underpinning for their unique practice of dispute resolution, whereas for the Stoics this Roman practice offered an unexpected opportunity to instrumentalise their conception of law.
Kenar bantlama makinesi kullanıcılarının sık karşılaştığı arızaların tespiti ve çözüm önerileri
Authors: KAYAHAN Kadir
Published: December 2022

Günlük hayatta kullanılan panel mobilyaların üretiminde, yarı mamül malzemenin üretime girmesinden ambalajlamaya kadar, birden fazla makine kullanılmaktadır. Kenar bantlama makinesi kenar bantlarını kesimi yapılan mobilya parçaların kenarlarına yapıştırmak için kullanılan bir makinedir. Bu çalışmada, mobilya endüstrisinde faaliyet gösteren firmaların AİM (Ağaç İşleme Makineleri) içerisinde en fazla kullandıkları kenar bantlama makinesinde ortaya çıkan arızaların belirlenmesi ve bu bağlamda arızaların muhtemel sebepleri ile çözüm önerilerinin belirlenmesi amaçlanmıştır. Bu sebeple, bu makineyi aktif olarak kullanan 50 işletmeye 12 sorudan oluşan anket uygulanmıştır. Toplanan anket formları SPSS paket programı ile istatistiksel olarak değerlendirilmiştir. Çalışma sonucunda araştırma yapılan işletmelerin %11.9 ’unun kazan yanması, % 2.8’inin ön freze arızası, % 1.8’inin radüs arızası, %8.3 ’ünün baş ve sonda bant bırakması, % 11’inin parçada kırıkların oluşması, % 32.1’inin bantlama esnasında makinenin durması, % 32.1’inin bantlanan parça üzerinde tutkal kalması sorunuyla karşılaştıkları görülmüştür. Çalışmanın son bölümünde ise arızaların giderilmesi için alınacak önlemlere ve çözüm önerilerine yer verilmiştir.
Evaluation
and conversion of temple waste flowers into incense sticks in Tumakuru district
of Karnataka, india
Authors: Dasalukunte Ananda Kiran , Halappa Kavitha
Published: December 2022

In any waste management process, the 3 R’s, i.e., Recycling, Reuse and Recover play a very important role. The present work focuses on collection, handling, and usage of waste flowers. A large volume of flower waste generated daily at Tumakuru is improperly disposed of in open places or in dust bins and finally reaches landfill along with the other municipal solid wastes. As a part of India’s Swachh Bharat programme, this paper gives an idea of reducing the flower waste quantity and converting them into incense sticks. The various types of flowers were analysed and compared based on the results obtained from physicochemical properties. SEM and EDS were used to determine the surface morphology and chemical compositions of crushed flowers, respectively. From the SEM study, it can be seen that filament type, cave type and stripelike textures were observed on the surfaces of crushed flowers, and the EDS analysis has shown that the rose flower powder has a rich amount of carbon (66.98 %) and yellow chrysanthemum flower contains less carbon (37.68 %) compared to other crushed flowers. Also, this paper demonstrates the practical aspects in making incense sticks from flower waste. It was suggested that dumping process must be managed with flexibility, following strict implementation of the applicable legislation, and awareness programs are needed to collect and reuse flower waste from different sources.
EFFECT OF SERVICE QUALITY ON CUSTOMER SATISFACTION AT METSKY DINE & LOUNGE BEKASI
Authors: Ishak Riani P. , Utami Nisa Rahmaniyah
Published: December 2022

The purpose of this study was to determine and analyze the effect of service quality on customer satisfaction at Metsky Dine & Lounge Bekasi.  This research uses descriptive research with a quantitative approach and simple linear regression analysis method.  The sampling technique uses accidental sampling. The population is all customers who come to Metsky Dine & Lounge Bekasi, while the total sample is 100 respondents based on the Slovin formula.  The results showed that the service quality variable has an effect on customer satisfaction at the Metsky Dine & Lounge Bekasi restaurant. It is hoped that Metsky Dine & Lounge Bekasi will continue to maintain and improve their service quality so customers continue to feel satisfied.
A Beleza do Contato: uma aproximação entre Eugène Minkowski e Paulo Freire
Authors: Silva Gabriel Barth da
Published: December 2022

O presente ensaio pretende, a partir da proposta fenomenológica do conceito contato vital de Eugène Minkowski, e do olhar materialista acerca do conceito boniteza formulado por Paulo Freire, propor um olhar transdisciplinar em que ambos os termos são dinamizados entre si para perceber sua complementaridade possível. Sejam por seus respectivos caráteres afetivos ou por suas dinâmicas inerentemente interpessoais, busca-se reiterar o potencial de interação entre ambos os conceitos para intervenções na realidade das Ciências Humanas em suas diversas esferas como, no presente caso, em torno da psicoterapia e de processos educacionais. Espera-se, ao final desse ensaio, gerar uma melhor compreensão acerca de potenciais contatos entre diferentes epistemologias, além de fomentar maiores debates em torno dos dois autores presentemente discutidos.
Os posicionamentos da psicologia no que se refere a medicalização escolar: Uma revisão bibliográfica
Authors: Silva Nathalia Tarnhovi da , Nakagawa Kezia Sumico
Published: December 2022

Este artigo analisa o posicionamento da psicologia diante da medicalização no âmbito escolar, no contexto histórico e cultural da sociedade contemporânea. A análise consiste em revisões bibliográficas de autores da Teoria da Psicologia Histórico-Cultural. Teoria esta que foi formulada por L. S. Vigotsky e A. R. Luria, psicólogos soviéticos, que consideram que para compreender o sujeito, deve-se considerar além das causas biológicas, considerar também todo o seu contexto social e histórico. Além disso, acredita-se que existe a relação entre o homem e o ambiente, na qual o homem modifica o ambiente e este modifica o homem, portanto, para que o sujeito possa existir enquanto homem, ele deve pertencer a um grupo social decorrente das interações humanas. Dessa forma, a queixa escolar envolvendo a medicalização no ambiente escolar, decorrente de diagnósticos que tentam justificar o fracasso escolar, sofrem forte influência da indústria farmacêutica, fenômeno este que vem acometendo a sociedade contemporânea e consequentemente as escolas, de forma geral, e precisam ser consideradas devidamente. Esta pesquisa traz o posicionamento da psicologia escolar mediante a temática da medicalização nesse âmbito e como a psicologia enquanto ciência, seguindo os conceitos da Teoria da Psicologia Histórico-Cultural, pode colaborar para que esse fenômeno seja reduzido nas escolas.
The landscape of nature-derived antimalarials-potential of marine natural products in countering the evolving Plasmodium
Authors: Prashar Cherish , Thakur Narsinh , Chakraborti Soumyananda , Areeb Hussain Syed Shah , Vashisht Kapil , Pandey Kailash C.
Published: December 2022

Malaria poses several challenges to the global research community on both diagnostic and therapeutic fronts. Most prominent of them are deletion of target genes (pfhrp2/3) used in rapid diagnostic tests (RDTs) and the emergence of resistance against frontline antimalarials by the evolving parasite. Exploration of novel therapeutics for malaria in view of limited vaccine options is a promising resort for malaria control and elimination. The scope of marine-derived chemotherapeutics is exciting, with a significant number of FDA-approved drugs or therapeutic leads under clinical trials for other diseases. This review article discusses the significant antimalarial potential of marine-derived natural products extracted from diverse biota including sponges, bacteria, sea hare and algae etc. Bioassay-guided fractionation of raw extracts from marine organisms for lead identification and further structural characterization of purified compounds compose a sustainable marine-derived drug discovery pipeline; which can be particularly diverted towards the exploration of antimalarials. It is to be noted that the Indian peninsula is largely unexplored, particularly for antimalarials screening; which has a huge marine biodiversity owing to the three distinct water bodies- Bay of Bengal, Indian Ocean and Arabian sea. This review also envisions a collaborative initiative to explore the potential of marine natural products in an economically feasible manner.
Scaling-up digital follow-up care services: collaborative development and implementation of Remote Patient Monitoring pilot initiatives to increase access to follow-up care
Authors: Azevedo Salomé , Guede-Fernández Federico , von Hafe Francisco , Dias Pedro , Lopes Inês , Cardoso Nuno , Coelho Pedro , Santos Jorge , Fragata José , Vital Clara , Semedo Helena , Gualdino Ana , Londral Ana
Published: December 2022

Background

COVID-19 increased the demand for Remote Patient Monitoring (RPM) services as a rapid solution for safe patient follow-up in a lockdown context. Time and resource constraints resulted in unplanned scaled-up RPM pilot initiatives posing risks to the access and quality of care. Scalability and rapid implementation of RPM services require social change and active collaboration between stakeholders. Therefore, a participatory action research (PAR) approach is needed to support the collaborative development of the technological component while simultaneously implementing and evaluating the RPM service through critical action-reflection cycles.

Objective

This study aims to demonstrate how PAR can be used to guide the scalability design of RPM pilot initiatives and the implementation of RPM-based follow-up services.

Methods

Using a case study strategy, we described the PAR team’s (nurses, physicians, developers, and researchers) activities within and across the four phases of the research process (problem definition, planning, action, and reflection). Team meetings were analyzed through content analysis and descriptive statistics. The PAR team selected ex-ante pilot initiatives to reflect upon features feedback and participatory level assessment. Pilot initiatives were investigated using semi-structured interviews transcribed and coded into themes following the principles of grounded theory and pilot meetings minutes and reports through content analysis. The PAR team used the MoSCoW prioritization method to define the set of features and descriptive statistics to reflect on the performance of the PAR approach.

Results

The approach involved two action-reflection cycles. From the 15 features identified, the team classified 11 as must-haves in the scaled-up version. The participation was similar among researchers (52.9%), developers (47.5%), and physicians (46.7%), who focused on suggesting and planning actions. Nurses with the lowest participation (5.8%) focused on knowledge sharing and generation. The top three meeting outcomes were: improved research and development system (35.0%), socio-technical-economic constraints characterization (25.2%), and understanding of end-user technology utilization (22.0%).

Conclusion

The scalability and implementation of RPM services must consider contextual factors, such as individuals’ and organizations’ interests and needs. The PAR approach supports simultaneously designing, developing, testing, and evaluating the RPM technological features, in a real-world context, with the participation of healthcare professionals, developers, and researchers.
Estimating causal effects of genetically predicted type 2 diabetes on COVID-19 in the East Asian population
Authors: Yoshikawa Masahiro , Asaba Kensuke , Nakayama Tomohiro
Published: December 2022

Background

Observational studies suggested that type 2 diabetes mellitus (T2DM) was associated with an increased risk of coronavirus disease 2019 (COVID-19). However, Mendelian randomization (MR) studies in the European population failed to find causal associations, partly because T2DM was pleiotropically associated with body mass index (BMI). We aimed to estimate the causal effects of T2DM on COVID-19 outcomes in the East Asian (EAS) population using a two-sample MR approach.

Methods

We obtained summary statistics from a genome-wide association study (GWAS) that included 433,540 EAS participants as the exposure dataset for T2DM risk and from COVID-19 Host Genetics Initiative GWAS meta-analyses (round 7) of EAS ancestry as the outcome dataset for COVID-19 susceptibility (4,459 cases and 36,121 controls), hospitalization (2,882 cases and 31,200 controls), and severity (794 cases and 4,862 controls). As the main MR analysis, we performed the inverse variance weighted (IVW) method. Moreover, we conducted a series of sensitivity analyses, including IVW multivariable MR using summary statistics for BMI from a GWAS with 158,284 Japanese individuals as a covariate.

Results

The IVW method showed that the risk of T2DM significantly increased the risk of COVID-19 susceptibility (odds ratio [OR] per log (OR) increase in T2DM, 1.11; 95% confidence interval [CI], 1.02–1.20; P = 0.014) and hospitalization (OR, 1.15; 95% CI, 1.04–1.26; P = 0.005), although the risk of severity was only suggestive. Moreover, IVW multivariable MR analysis indicated that the causal effects of T2DM on COVID-19 outcomes were independent of the effect of BMI.

Conclusions

Our MR study indicated for the first time that genetically predicted T2DM is a risk factor for SARS-CoV-2 infection and hospitalized COVID-19 independent of obesity in the EAS population.