bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of Supplemented Shengmai San (SMS) on Blood Biochemistry and HSP72 Expression in Peripheral Blood of Flying-saucer Athletes before and after High Temperature Training
Authors: Shen Jian , Xu Feng , Jin Bin , Zhang Rongquan
Published: December 2020

Objective: The purpose of this paper is to study the effects of supplemented Shengmai San on the expression of heat shock protein 72 (HSP72) and blood biochemistry in peripheral blood of flying-saucer athletes before and after high temperature training, so as to provide experimental basis for enhancing thermal endurance and preventing heat disease of flying-saucer athletes with anti-heat disease drugs. Methods: 24 flying-saucer athletes from Zhejiang province were selected and divided into two groups, including control group and traditional Chinese medicine group with 12 people in each group. Among them, those who did not drink supplemented Shengmai San were in the control group, while those who drank it were in the traditional Chinese medicine group. During summer training, high temperature training task was carried out for 2 weeks. Flying-saucer athletes in traditional Chinese medicine group were given supplemented Shengmai San before training every morning and afternoon. Peripheral venous blood of each group was extracted before experiment and 2 weeks later and lymphocyte HSP72 content, blood routine and biochemical indexes were determined respectively. Results: Before the experiment, there were no abnormal phenomenon blood routine, biochemical test value and HSP72 expression in the control group and the traditional Chinese medicine group. After comparison, there was no significant difference (P>0.05). After the high temperature training, the expression of HSP72 in the Chinese medicine group was significantly higher than that before the training and control group (P<0.05). There were significant differences in white blood cell count before and after the experiment (P<0.05). Conclusion: Taking supplemented Shengmai San can significantly increase expression of HSP72 in up-regulation of flying saucer athletes after thermal stimulation, thus enhancing thermal tolerance and preventing thermal diseases.
Pengaruh Kegiatan Literasi dalam Peningkatan Minat Baca Siswa Kelas VIII SMP Negeri 2 Kota Ternate
Authors: Sasmayunita
Published: November 2020

Peneltian ini mengulik seputar minat baca pada siswa kelas VIII SMP Negeri 2 Kota Ternate, yang dapat ditumbuhkan melalui kegiatan literasi. Penelitian ini menggunakan pendekatan kualitatif yang berlokasi pada SMP Negeri 2 Kota Ternate. Waktu penelitian dimulai pada tanggal 19 November sampai dengan 19 Desember 2019 dan disesuaikan dengan jadwal mata pelajaran bahasa Indonesia yang berlaku di sekolah. Pengambilan data dilakukan dengan cara  observasi, wawancara, dan angket. Penelitian ini menyimpulkan hasil bahwa kegiatan literasi terhadap minat baca pada siswa kelas VIII SMP Negeri 2 Kota Ternate sangat cukup. Pengaruh kegiatan literasi terhadap minat baca siswa kelas VIII SMP Negeri 2 Kota Ternate memiliki pengaruh sesuai dengan hasil data, menunjukan bahwa hasil tes siswa dengan interval nilai 60-69% atau sesuai pada aspek kesesuaian antara perencanaan dan peleksanaan kegiatan literasi terdapat 17 responden yang sesuai dan 10 siswa yang tidak sesuai 30-39%. Aspek kelamaan kegiatan literasi pada pengaruh kegiatan literasi terhadap minat baca atau dapat dipersentasikan menjadi 56% atau interval nilai 50-59 terdapat 15 responden  yang sesuai, dan 12 responden yang tidak sesuai 44%. Aspek perkembangan hasil kemampuan membaca siswa 16 responden sesuai  atau interval nilai 50-59% dan 11 responden yang tidak sesuai dengan interval nilai 40-49%.  Dan aspek perencanaan ke tahap selanjutnya terdapat 15 responden yang sesuai atau interval nilai 50-59% dan 12 responden dengan kualifikasi nilai 40-49% yang tidak sesuai. Dengan demikian scara keseluruhan dari empat aspek dengan interval nilai dengan persentase dapat dikategorikan “sedang” Pencapaian tujuan pendidikan adalah keinginan semua orang baik pendidik maupun peserta didik, olehnya itu dalam pebelajaran yang perlu diperhatikan adalah selain peran guru juga peran siswa yang perlu diperhatikan, agar pencapaian tujuan pembelajaran terutama minat baca bisa dinikmati dan dipahami oleh peserta didik.
Makna Kelong Salonreng pada Upacara Adat Perkawinan Masyarakat Desa Ara Kabupaten Bulukumba (Suatau Tinjauan Semiotika Marcel Danesi)
Authors: Runimeirati
Published: November 2020

ABSTRAK

Penelitian ini bertujuan menganalisis makna kelong Salonreng dalam sebuah ritual adat di masyarakat Bulukumba, mengkaji totalitas makna kelong Salonreng berdasarkan teori semotika Marcel Danesi. Penelitian ini adalah penelitian kepustakaan dan merupakan penelitian deskriptif kualitatif. Sumber sata dari penelitian ini adalah keseluruhan makna kelong Salonreng. Data primer diperoleh dari beberapa informan yang paham dan tahu soal objek penelitian. Teknik pengumpulan data pada penelitian ini adalah secara observasi, wawancara, dokumentasi, dan pencatatan. Sedangkan, teknik analisis datanya yaitu dengan mengidentifikasi semua pesan dan tanda teks kelong Salonreng, transliterasi dan pengklasifikasian makna. Dapat disimpulkan yakni (1) Setiap bait dalam teks Salonreng merupakan bentuk kesyukuran masyarakat Ara kepada Sang Pencipta, (2) Pola persajakan kelong Salonreng serupa dengan pola persajakan Makassar 8-8-4-8, (3) Tari Saloreng merupakan perkembangn dari tari rakyat dengan gerakan yang sangat sederhana yang dimainkan secara tunggal ataupun berkelompok penari wanita, (4) Sebagai penghormatan kepada leluhur atau digunakan untuk menghalau roh-roh jahat serta memohon perlindungan dari Dewata.

Kata kunci : Kelong Salonreng, Semiotik dan Kabupaten Bulukumba.
Pembelajaran Kolaboratif Jumping Tasks pada Materi “Macam-Macam Pekerjaan” Siswa Kelompok B1 Paud Santo Yoseph Kota Ternate
Authors: Farida Samad  , Rosita Wondal  , Sasmayunita
Published: November 2020

Jumping tasks merupakan aktivitas pembelajaran dengan pemberian masalah berdasarkan tingkat kesulitanyang lebih tinggi untuk meningkatkankemampuan siswa.Penelitian ini bertujuan untuk mendeskripsikan kegiatan pembelajaran kolaboratif jumping tasks pada materi ‘Macam-macam Pekerjaan’ di kelompok B PAUD Santo Yoseph Kota Ternate. Teknik pengumpulan data dilakukan dengan metode observasi dan dokumenter.Analisis data kualitatif menggunakan model interaksi Miles and Huberman.Rata-rata hasil penelitian menunjukkan bahwa pembelajaran kolaboratif jumping task pada materi ‘Macam-Macam Pekerjaan’ di kelompok B1 PAUD Santo Yoseph Ternate sebesar 46,15%siswa yang dapat menyelesaikan dengan kategori berkembang sesuai harapan dan sangat baik, namun 53,85% siswa belum dapat menyelesaikan secara tuntas (masih dalam tahap mulai berkembang). Disarankan bahwa guru perlu membiasakan siswa untuk mengembangkan pola berpikir tingkat tinggi dengan memberikan tantangan (jumping task) sehingga siswa terbiasa untuk mengembangkan kemampuan berpikir dalam menyelesaikan masalah yang diberikan guru.
Analisis Faktor Sosial Pemertahanan Bahasa Dentong di Kabupaten Maros
Authors: Kasmawati  , Fitrawahyudi
Published: November 2020

Penelitian ini bertujuan untuk mengungkap faktor-faktor sosial penggunaan bahasa Dentong melaui indikator sikap bahasa pengguna bahasa, serta untuk mengetahui daya hidup bahasa maka akan dilakukan pengukuran daya hidup bahasa Dentong berdasarkan penggunaan bahasa pada usia dibawah 25 tahun (usia produktif bertahannya bahasa). Metode yang digunakan dalam penelitian ini yakni metode survei, observasi dan wawancara, metode survei menggunakan kuesioner digunakan untuk mengungkap faktor-faktor sosial penggunaan bahasa Dentong, sedangkan metode observasi dan wawancara digunakan untuk memproyeksi daya hidup bahasa Dentong. Analisis data yang digunakan yaitu analisis data secara bertahap melalui kegiatan reduksi data, model data (display data) dan penarikan/verifikasi kesimpulan. Hasil penelitian dapat disimpulkan bahwa pemertahanan bahasa Dentong berada dalam kategori baik, didasari atas persentase penggunaan bahasa pada seluruh kelompok usia sebesar 93% yang masih menggunakan bahasa Dentong dan penggunaan bahasa Dentong sebagai alat interaksi utama baik dalam komunikasi intrakeluarga, maupun antar keluarga.
Perlindungan Hak Moral dan Hak Ekonomi terhadap Konten Youtube yang Dijadikan Sumber Berita
Authors: Ginting Antonio Rajoli
Published: December 2020

Konten YouTube sebagai salah satu karya sinematografi yang dilindungi oleh hak cipta. Konten YouTube tersebut seringkali dijadikan sumber berita oleh media massa online. Materi konten YouTube yang diambil menjadi berita seringkali tidak melakukan permohonan izin terlebih dahulu kepada pencipta konten tersebut. Hal ini dapat merugikan pemilik konten apalagi kalau materi berita tersebut berbeda dengan isi konten yang diterbitkan. Sehingga rumusan masalah yang diangkat adalah bagaimana bentuk pelanggaran dan perlindungan hak moral dan hak ekonomi atas konten YouTube yang dijadikan berita dan bagaimana penyelesaian sengketanya. Penelitian ini merupakan penelitian hukum normatif yang bersifat deskriptif. Hasilnya adalah pelanggaran yang dilakukan dengan memuat berita yang tidak sesuai dengan konten YouTube dan tidak memohon izin terlebih dahulu kepada pemilik konten untuk dijadikan berita dimana media massa tersebut memperoleh keuntungan. Perlindungan hak moral dan hak ekonomi dilakukan dengan cara delik aduan yang dapat disampaikan kepada penyidik maupun dewan pers. Penyelesaian sengketa dapat dilakukan melalui jalur litigasi ke Pengadilan Niaga ataupun melalui jalur non litigasi yakni mediasi. Hak moral dan hak ekonomi terhadap konten yang dijadikan sebagai sumber berita dapat dilindungi dengan melakukan berbagai upaya hukum. Saran penulis dalam kajian ini adalah perlunya pengawasan yang baik dalam menciptakan perlindungan yang maksimal terhadap konten YouTube.
PEMBERDAYAAN PENYANDANG DISABILITAS OLEH DINAS SOSIAL KOTA KEDIRI
Authors: Krisnada Krisnada , Widodo Sugeng
Published: November 2020

Abstract People with disabilities have physical and mental disabilities that have differences when compared to normal people, therefore there needs to be special attention from the government to empower or positive activities that are useful to hone the skills of the people with stability. Therefore, the role of the government is necessary for the development of people with disabilities. Through social services empowerment of people with disabilities is more targeted and focused. The purpose of this research is to decrypt what efforts are made as well as what obstacles are faced in the empowerment of people with disabilities. The type of method used in this study is a descriptive method with a qualitative approach. Data collection techniques used are, observation, interview, documentation. The result of this research is that the efforts made by Social Services are social assistance for severe disabilities in the form of money, as well as training but stalled per the year 2018 because it is focused in Dipnaker. Besides, there is assistance from the ministry in the form of non-cash social assistance for all classifications of people with disabilities. There are also other supporting activities as well as UPSK from the Social Service of East Java Province.  Keywords: empowerment; disability; government role Abstrak Para penyandang disabilitas memiliki kelemahan secara fisik dan mental yang memiliki perbedaan bila dibandingkan dengan orang-orang normal, oleh sebab itu perlu adanya perhatian khusus dari pemerintah untuk memberdayakan ataupun kegiatan yang bersifat positif yang berguna untuk mengasah kemampuan para penyandang stabilitas. Maka dari itu peran pemerintah sangatlah perlu dalam pembinaan penyandang disabilitas. Lewat Dinas Sosial pemberdayaan penyandang disabilitas lebih terarah dan fokus. Tujuan penelitian ini untuk mendekripsikan upaya apa yang dilakukan serta kendala apa yang dihadapi dalam pemberdayaan penyandang disabilitas. Jenis metode yang digunakan dalam penelitian ini adalah metode deskriptif dengan pendekatan kualitatif. Teknik pengumpulan data yang digunakan yaitu, observasi, wawancara, dokumentasi. Hasil dari penelitian ini adalah upaya yang dilakukan Dinas Sosial adalah bantuan sosial untuk disabilitas berat berupa uang, dan juga pelatihan namun terhenti pertahun 2018 karena difokuskan di Dipnaker. Selain itu terdapat bantuan dari kemensos berupa bantuan sosial non tunai untuk semua klasifikasi penyandang disabilitas. Terdapat juga kegiatan penunjang lain dan juga UPSK dari Dinas Sosial Provinsi Jawa Timur.Kata Kunci: pemberdayaan; penyandang disabilitas; peran pemerintah
GRİ TAHMİN VE BOX-JENKINS YÖNTEMLERİ İLE ANTALYA LİMANI İÇİN AYLIK KONTEYNER TALEP TAHMİNİ
Authors: ALTİN Fatma Gul , ÇELİK EROĞLU Şeyma
Published: November 2020

Konteyner taşımacılığının, denizyolu ticaretindeki önemi her geçen gün artmaktadır. Konteyner hacminin etkili tahmini ise liman planlaması ve işletimi için bir karar desteği sağlamaktadır. Bu nedenle liman yönetimlerinin geleceğe yönelik planları açısından tahminleme çalışmaları önemli bir rol oynamaktadır. Bu çalışmada, Antalya’da bulunan Port Akdeniz Limanı için yapılan tahmin modellerinde Ocak 2008-Aralık 2017 (120 ay) dönemi konteyner istatistikleri veri seti olarak kullanılmıştır. Liman işletmesinin yük talep tahmini, konteyner bazında ve mevsimsel farklılıklar dikkate alınarak, Ocak 2018-Aralık 2019 (24 ay) dönemi için yapılmıştır. Gri Tahmin ve Box-Jenkins yöntemlerinin kullanıldığı çalışmada, konteyner tahminleri Gri Model (1,1) ve ARIMA (0,1,0)x(0,1,1)12 modelleri ile analiz edilmiştir. Tahmin sonuçları başarı kriterleri ile değerlendirildiğinde, Gri Model (1,1)’in MAPE ve MAE değerlerinin daha düşük olduğu gözlemlenmiştir. Ancak hem RMSE ve MSE hem de sapma değerleri dikkate alındığında ise; ARIMA (0,1,0)x(0,1,1)12 modelinin daha iyi ve uygun tahmin değerleri verdiği tespit edilmiştir.
TOURIST PERCEPTIONS ABOUT FOOD SERVICE CHARACTERISTICS IN ACCOMMODATION ENTERPRISES: AN IMPORTANTANCE-PERFORMANCE ANALYSIS
Authors: YURCU Gülseren , AKINCI Zeki , KÜÇÜKER Caner
Published: November 2020

This study purposed to evaluate food-service characteristic perceptions according to tourists spending their holidays in accommodations enterprises in the region of Alanya\Okurcalar. The population of the study consisted of 382 people, who were selected through convenience sampling method on voluntary basis. The data obtained through the survey method were evaluated via importance-performance analysis method, which is based on the comparison of the importance of the characteristic of an issue or dimension examined and performance perceptions of these characteristic on a matrix. The characteristic that need to be maintained included hygiene and general cleanliness, courtesy and friendliness of service staff, well-groomed and clean service staff, accommodation enterprises facilities, dining atmosphere and speed of service delivery. The characteristics that need to be concentrated on comprised music and image portrayed, service equipment, menu diversity and menu presentation while the characteristics with low priority consisted of staff service skills and knowledge, food service style, food price and value for money, and product serving. Another remarkable finding of this study is that there were no possible overkills in food services as perceived by tourists. This finding is satisfactory in terms of showing that scarce resources are optimally used in accommodation enterprises.
BABACAN LİDERLİK, YILDIRMA VE ÖRGÜTSEL SİNİZM İLİŞKİLERİNDE BİREYCİ VE TOPLULUKÇU KÜLTÜREL DEĞERLERİN ROLLERİ
Authors: DURMAZ Cemil , ERGENELİ Azize , METİN CAMGÖZ Selin
Published: November 2020

Farklı liderlik uygulamalarının hangi koşullarda daha uygun olabileceğini belirlemeye yönelik araştırmaların bazıları liderin ve/veya izleyenlerinin niteliklerine, bazıları ise örgütün ve toplumsal kültürel değerlerin özelliklerine odaklanmıştır. Bu çalışmada, öncelikle babacan liderlik-örgütsel sinizm ilişkisinde, yıldırmanın aracılık etkisi incelenmiş ve ardından yöneticilerin babacan liderlik uygulamaları durumunda, çalışanların bu davranışları ne ölçüde yıldırmacı olarak algılamalarının, bireyci ya da toplulukçu kültürel değerlere göre değişiklik gösterip göstermediği araştırılmıştır. Veriler bir Organize Sanayi Bölgesinde faaliyet gösteren farklı sektörlerde çalışan 333 kişiden anket yolu ile elde edilmiştir. Babacan Liderlik, İşyerinde Psikolojik Taciz, Örgütsel Sinizm ve Bireyci-Toplulukçu (INDCOL) Kültürel Değerler Ölçekleri uygulanmıştır. Çalışmanın hipotezleri, Hayes (2018) tarafından önerilen PROCESS makrosu kullanılarak aracılık ve düzenleyicilik analizleri ile test edilmiştir. Bulgular, yıldırma algısının babacan liderlik ve örgütsel sinizm arasında aracılık rolüne sahip olduğunu ortaya koymuştur. Tespit edilen bu aracılık etkisinin, bireyci ve toplulukçu kültürel değerler açısından farklılaşmadığı da görülmüştür. Öte yandan, yöneticilerinin babacan liderlik uygulamaları ile çalışanların yıldırma algıları arasındaki ilişkide, bireyci ve toplulukçu kültürel değerlerin düzenleyici etkisini belirlemeye yönelik olan analizlerde, sadece toplulukçuluğun, düzenleyici etkisi olduğu anlaşılmıştır. Diğer bir ifadeyle, yüksek toplulukçu değerlere sahip çalışanları, yöneticilerini babacan lider olarak algıladıklarında daha düşük seviyede yıldırma hissettikleri tespit edilmiş, ancak benzer bir düzenleyici etki bireycilik kültürel değişkeni açısından doğrulanmamıştır.
Assessing the remote management of Family Medicine education during the SARS-CoV-2 Pandemic
Authors: Tarraga Lopez Pedro J. , Navarro Sanchez Lourdes , Sadek Ibrahim M.
Published: November 2020

Introduction: The SARS-CoV-2 (COVID-19) coronavirus pandemic has changed lifestyles, work styles and, of course, training and teaching.
Objective: To evaluate the telematic training of the subject of family medicine at the University of Castilla la Mancha.
Methods: it was proposed to implement a methodology of telematic classes, allowing the student to self-manage their time and receive the contents at distance. The acceptance of the new methodology was subsequently evaluated through satisfaction surveys and the effect of the methodology on the students’ grades was evaluated comparatively.
Results: Favorable results were obtained with a global average for the course of 4.95 out of 5 for the year 2020 and 4.85 and 4.87 for the years 2018 and 2019. The specks obtained above all in the theory exam are higher than that of these years.
Conclusion: It is concluded that the telematic approach is a learning methodology valued positively by the students with a favorable impact on their academic results.
Faktor-Faktor yang Mempengaruhi Minat Teknopreneur Melalui Motivasi pada Mahasiswa
Authors: Marti'ah Siti , Theodora Berta Dian
Published: November 2020

Entrepreneur day participants for 3 years in general have always increased in number, but unfortunately the number of participants in the technopreneurship business field is less than expected, in 2019 there were 3 participants out of 160 participants. This amount is relatively small so that a research is needed concerning on what factors can influence student’s motivation and interest in becoming a technopreneur in informatics students. This study used a quantitative approach to the path analysis method with independent variables, namely internal and external factors, entrepreneurship motivation as an intervention variable and technopreneur interest as the dependent variable. The research sample wad students who had taken entrepreneurship courses in the informatics study program as many as 300 students. The results showed that internal factors and external factors influenced entrepreneurial motivation by 36.4%. Entrepreneurial interest was directly influenced by internal factors and entrepreneurial motivation, while external factors did not directly affect the interests of technopreneur and needed to be through entrepreneurial motivation.
A Study on the Relationship between Iron Reserves and the Intensity of Coronary Artery Stenosisin Angiography Candidates
Authors: Mahmoodi Khalil
Published: November 2020

Various risk factors including blood iron may create coronary artery diseases and lead to myocardial infarction. There are controversies with regard to the impact of blood iron on myocardial infarction. Therefore, the aim of this paper was to investigate the relationship between iron reserves and the intensity of coronary artery stenos is among angiographic candidates in Zanjan, Iran. This was a cross sectional study. Samples were consisted of patients who were hospitalized for diagnostic coronary angiography in hospitals in an urban area of Iran. A convenient sampling method was used to recruit samples via interviews and laboratory examinations for FBS, iron, TIBC, ferritin, creatinine serum, CBC, cholesterol, HDL and LDL. The samples were divided into control and intervention groups. After coronary angiography, the intervention group was evaluated by four different methods including the extent score, stenos is score, vessel score and Duke CAN Index. The samples were consisted of 89 men (60.1%) and 59 women (39.9%). The levels of ferritin (p=0.003) and iron (p=0.002), and transferrin saturation percent (p=0.002) showed significant differences between males and females (p=0.004)
Recognizing Early Warning Signs for Patient Safety: Study in Pakistan’s Tertiary Care Hospital
Authors: Soomro Rufina
Published: November 2020

It is not uncommon for hospitalized patients to exhibit early warning signs before deteriorating. Clinical deterioration can happen at any point in a patient’s illness, or care process. Nurses are expected to have skills to enable them to assess precisely the severity of deterioration, as nurses are the first to encounter the patients. In keeping views we as team have develop module on Recognition of Early Warning signs for Nurses to assess their knowledge, educate them and reassess their knowledge
The Impact of Online Video Learning Activities on Nurses’ and Midwives’ Continuing Professional Education
Authors: Wilson Anne
Published: November 2020

New knowledge/skills from CPD provides increased confidence to advocate for best practice; New knowledge/skills result in improved selfefficacy enabling better patient care and better patient education; CPD fosters leadership skills and confidence in demonstrating influence on health outcomes; The benefit of continuing professional education in improving competence is identified; The major benefits of online learning are convenience and increase accessibility to education
On the macromycetes of Taseevo District (Krasnoyarsk Territory, East Siberia)
Authors: Kosheleva A. P. , Kutafjeva N. P.
Published: December 2020

The species composition of macrofungi was studied in Handala and Veseloe villages of Taseevo District (Krasnoyarsk Territory) in July — August 1999–2005. As a result, 119 macrofungi species were recorded for the first time for the area investigated; 45 species are new to Krasnoyarsk Territory. In total, 248 macrofungi species of 101 genera are known for Taseevo District.
The macromycetes of Stolby State Nature Reserve (1916–2005)
Authors: Kosheleva A. P. , Kutafjeva N. P.
Published: December 2020

The species composition of macrofungi was investigated in the northern and central parts of Stolby State Nature Reserve in the Eastern Sayan (Krasnoyarsk Territory) in July — August 2003–2005. As a result of our research, we have revealed 103 macrofungi species new to the Reserve, 46 species new to the Krasnoyarsk Territory, and one species [Clitopilus hobsonii (Berk. et Broome) P. D. Orton] new to Russia. In total, 200 macrofungi species of 111 genera are recorded for Stolby State Nature Reserve. Seven species are cultivated in pure cultures in the Laboratory of Biochemistry of Fungi (LE, BIN).
Tác giả Việt nêu quan điểm về việc rút bài báo khoa học trên Nature
Authors: AISDL
Published: November 2020

Tác giả Vương Quân Hoàng (Trung tâm Nghiên cứu Xã hội Liên ngành ISR, trường Đại học Phenikaa) vừa có bài viết quan điểm trên tạp chí Nature về việc làm thế nào để việc rút bài báo khoa học trở nên minh bạch hơn, mang lại lợi ích cho bản thân nhà khoa học bị rút bài cũng như cộng đồng khoa học.
Persaudaraan
Authors: Hasanah Uswatun
Published: November 2020

Persaudaraan adab satu landasan yang menjadikan umat bersatu
Interleukin-1α and the interleukin-1 receptor antagonist (IL-1RN) are differentially expressed in the primary tumors of breast cancer patients treated with trastuzumab.
Authors: Mamoor Shahan
Published: November 2020

Trastuzumab, a monoclonal antibody targeted against the human epidermal growth factor receptor 2 (HER2) is utilized for the treatment of human breast cancer (1, 2), but a complete understanding of how tumor signal transduction is modulated by trastuzumab treatment is lacking. By mining published and public microarray and gene expression data (3, 4) from the primary tumors of patients treated with trastuzumab, we found that two components of the interleukin-1 cytokine signaling pathway, interleukin-1α (IL-1α) and the interleukin-1 receptor antagonist, IL-1RN, were among the genes most differentially expressed in the primary tumors of patients treated with trastuzumab. While IL-1α cytokine levels were increased, IL-1RN levels were decreased. Thus, the administration of trastuzumab in patients with breast cancer is associated with increased expression of a cytokine demonstrated to promote breast cancer progression and decreased expression of an interleukin receptor antagonist with metastasis suppressive properties in breast cancer human xenograft models in vivo (5, 6).
K3 DALAM KEPERAWATAN di RUMAH SAKIT
Authors: Minannisa Cindy
Published: December 2020

K3 adalah upaya yang bertujuan untuk meningkatkan dan memelihara derajat kesehatanfisik, mental dan sosial yang setinggi-tingginya bagi pekerja di semua jenis pekerjaan,pencegahan terhadap gangguan kesehatan pekerja yang disebabkan oleh kondisi pekerjaan;perlindungan bagi pekerja dalam pekerjaannya dari risiko akibat faktor yang merugikankesehatan. Keperawatan merupakan suatu bentuk pelayanan profesional bersifat humanistik,menggunakan pendekatan holistik, dilakukan berdasarkan ilmu dan kiat keperawatan,berorientasi kepada kebutuhan objektif klien. Rumah Sakit (RS) termasuk dalam kriteria tempatkerja dengan berbagai ancaman bahaya yang berdampak kepada kesehatan, tidak hanya terhadappara pelaku langsung yang bekerja di RS, tapi juga terhadap pasien maupun pengunjung RS.Sehingga seharusnya pihak pengelola RS menerapkan upaya-upaya K3 di RS. Tujuan: untukmengetahui bagaimana k3 dalam keperawatan di rumah sakit. Metode: Tugas ini menggunakanmetode Literature review dimana dilakukan dengan cara menganalisis kajian dan eksplorasijurnal, text book, maupun e-book yang relevan dan membahas tentang hal-hal mengenai k3dalam keperawatan di rumah sakit. Hasil: Hasil dari pengkajian ini dengan menggunakanmetode literatur review adalah dengan membaca pengkajian ini pembaca dapat menegetahuitujuan, manfaat dan berapa penting k3 dalam keperawatan di terapkan di rumah sakit.
PENELITIAN RASULULLAH TERHADAP SYAIR
Authors: Widiyanti Lina Eriana
Published: November 2020

Sya’ ir di golongan bangsa arab ialah suatu kebangsaan untuk mereka. Apalagi, saat sebelum islam tiba, Ka’ bah di peruntukan bagaikan tempat buat melaksanakan kompetensi pembacaan syi’ ar. Terdapat tempat lain yang mereka pakai semacam pasar Ukaz. Ketinggian keahlian mereka menyusun, mencerna kata serta mengantarkan ialah salah satu fakta ketinggian kebudayaan mereka. Rasanya keahlian mareka bersya’ ir ini ialah salah satu pemicu mu’ jizat terbanyak Rasulullah saw merupakan al- quran yang memakai uslub yang melebihi apa yang mereka miliki. Dari sejarah di tahu kalau mu’ jizat yang di bagikan oleh para Nabi saw melebihi keahlian warga pada waktu itu.
Glycine-N-acyltransferase (GLYAT) is differentially expressed in brain metastatic breast cancer.
Authors: Mamoor Shahan
Published: November 2020

Metastasis to the brain is a clinical problem in patients with breast cancer (1-3). We mined published microarray data (4, 5) to compare primary and metastatic tumor transcriptomes to discover genes associated with brain metastasis in patients with metastatic breast cancer. We found that the glycine-N-acyltransferase, encoded by GLYAT, was among the genes whose expression was most different in the brain metastases of patients with metastatic breast cancer as compared to primary tumors of the breast. Molecular functions and down-regulation of GLYAT may be important for metastasis of primary tumor-derived cancer cells to the brain in humans with metastatic breast cancer.
Tuberous sclerosis complex 2 (TSC2) is differentially expressed in the tumors of breast cancer patients treated with trastuzumab.
Authors: Mamoor Shahan
Published: November 2020

Trastuzumab (Herceptin) is a monoclonal antibody targeting the extracellular domain of the human epidermal growth factor receptor 2 (HER2) (1) utilized for the treatment of adjuvant and metastatic breast cancer (2) in the United States and worldwide. We mined published microarray and gene expression data (3, 4) to discover in an unbiased manner the most significant transcriptional changes associated with trastuzumab treatment. We identified tuberous sclerosis complex 2, encoded by TSC2, as among the genes most differentially expressed in the primary tumors of patients with breast cancer treated with trastuzumab. The primary tumors of breast cancer patients treated with trastuzumab expressed higher levels of TSC2 messenger RNA than did patients not treated with trastuzumab, and a single administration of trastuzumab was sufficient to result in differential expression of TSC2 in primary tumors of the breast, demonstrating increased expression of a molecule that interacts with AMP-activated protein kinase (AMPK) to protect cells from glucose-deprivation induced cell death (5) as a direct transcriptional result of treatment with trastuzumab.
The Promotion of Graduate Programs through Clustering Prospective Students
Authors: AISDL
Published: November 2020

The promotion of academic programs, particularly at graduate levels, emerges as a response to market changes.In general, graduate programs are not a first order necessity which makes necessary the right promotion of suchprograms guarantee the attraction of prospective students, which enroll in some of them, which is essential forthe financial sustainability of universities. Notably, the last one is a crucial problem for private universities.In this paper, we analyze the prospective students that enroll in a private to design better promotion strategiesby using on data gathered by online sources. Specifically, we use clustering techniques to define marketingstrategies based on segments of students. We find that age and city are crucial to promoting graduate programswhile marital status and sex does not impact the decision of students in the university that we analyze.
REALISASI IMAN DALAM KEHIDUPAN SOSIAL
Authors: Rahman Fitriyani Rahman
Published: November 2020

Iman merupakan keyakinan yang dibenarkan oleh hati, di ikrarkan oleh lisan, dan di buktikan dengan perbuatan, kemudian adapun orang-orang yang mengaku beriman, tetapi pengakuan tersebut tidak dibuktikan dengan perilaku yang menunjukkan bahwasanya seseorang tersebut itu beriman, maka dari itu betapa pentingnya bersosialisasi dalam kehidupan nyata dalam suatu perilaku, karna perilaku itu dapat menunjukkan seseorang yang beriman dan iman tidak sekedar pengakuan hati.
Tiếp biến văn hóa tại Việt Nam đầu thế kỉ 20: “Nơi tầng 2 - Phố Phái”
Authors: AISDL
Published: November 2020

Trong quãng thời gian nhàn rỗi, họa sĩ Bùi Xuân Phái trò chuyện với bạn bè ở quán café Lâm, nơi ông tìm cảm hứng sáng tác về Hà Nội. Là người Hà Nội gốc, họa sỹ gắn bó với khu phố cổ từ nhỏ.
20 Hadis Takdir Agus Nurasikin 181370064 IHB5
Authors: Nurasikin Agus
Published: November 2020

Secara bahasa, hadis berarti berbicara, perkataan, percakapan. Hadis disebut juga 'Sunnah', yang secara istilah berarti segala perkataan (sabda), perbuatan, ketetapan dan persetujuan dari Nabi Muhammad SAW yang dijadikan landasan syariat Islam. Dan makalah ini berisi 20 hadis tetang takdir lengakap disertai keterangan nya.
ABD6: MHC Class I A*0201-LLFGYPVYV-B7 TCR complex: convergence diagnostics of number density
Authors: Antipas Georgios S.E. , Ntallis Nikolaos , Karalis Konstantinos
Published: November 2020

ABD6: MHC Class I A*0201-LLFGYPVYV-B7 TCR complex: convergence diagnostics of number density
Optimal Power Allocation Between Beam Tracking and Symbol Detection Channels in a Free-Space Optical Communications Receiver
Authors: Bashir Muhammad Salman , Alouini Mohamed-Slim
Published: November 2020

Free-space optical (FSO) communications will play an important role in the backhaul of future generation of wireless networks in order to support high data rates. Because of narrow beamwidth inherent to an optical signal, acquisition and tracking form an important component of any FSO communication system. In this study, we have analyzed the optimization of received power allocation between tracking and data channels in an FSO receiver. The objective function that is optimized (minimized) are the probability of error and the probability of outage, and the optimization of power allocation is carried out as a function of parameters such as noise power, pointing error variance, pointing error correlation coefficient, and the threshold of outage. We have analyzed the optimization concerning the lognormal and exponentiated Weibull fading scenarios as well. We learn that the optimal power allocation is a function of the received signal-to-noise ratio: a lower signal-to-noise ratio dictates that a higher fraction of received power should be diverted to the tracking channel and vice versa.
A Cyber-secure Framework for Power Grids Based on Federated Learning
Authors: You Shutang
Published: November 2020

Cyber security is important of power grids to ensure secure and reliable power supply. This paper presented a cyber- secure framework for power grids based on federated learning. In this framework, each entity, which may be a distribution/transmission/generation service provider or even a customer, can contribute to the overall system immunity and robustness to cyber-attacks, while not required to share local data, which may have privacy, legal and property concerns. The main idea is to use the federated learning framework to share the knowledge learned from local data instead of sharing power grid data itself. With complete knowledge learned from all data from the power grid, each entity is better positioned to defend the cyber-attacks and improve power grid resiliency. Future work on applying this federated learning based framework in power systems is also discussed.
Can object difficulty be predicted based on disfluencies and eye movements in connected speech?
Authors: Pistono Aurélie , Hartsuiker Robert
Published: November 2020

To reveal the underlying cause of disfluency, several authors use a network task, where participants describe the route taken by a marker through visually presented networks of objects. To be able to disentangle disfluency related to word preparation from other factors, we combined this task with eye-tracking. We asked whether delays in the earliest stages of picture naming elicit disfluency. We therefore used visual blurring which hinders visual identification of the items and thereby slows down selection of a lexical concept. This manipulation did not lead to more disfluency on average and viewing times decreased with blurred pictures. However, multivariate pattern analyses revealed that a classifier could predict, from the pattern of disfluency, whether each participant was about to name blurred or control pictures. Impeding the conceptual generation of a message therefore affected the pattern of disfluencies of each participant individually, but this pattern was not consistent from one participant to another.
Distinct behavioral effects and neural mechanisms of reciprocal reputation on cooperative decision-making in gain and loss context
Authors: Gong Xu , Sanfey Alan , zhou xiaolin , Luo Yuejia
Published: November 2020

Cooperation is essential for society’s functioning, while reciprocity is one of the most critical factors for establishing and maintaining cooperative social relationships. Until now, however, the majority of studies exploring human social cooperation were in a sharing gain frame. The present study investigates the behavioral effects and neural correlates of other people’s prior history of reciprocal reputation on cooperative decisions in both gain and loss contexts. 39 Chinese adult subjects participated in the study. Participants first played a Trust Game as Trustee to understand how we quantify the reciprocal reputation and then joined a modified Public Goods Game framed in gain and loss contexts with partners with various reciprocity levels. Behaviorally, individuals tended to be more cooperative with higher reciprocal reputation partners than lower ones, contributing a higher percentage of gain and a lower percentage of loss to the public pool. This effect was robust, especially in the gain context. Trial-wise mixed-effect regression results further demonstrated that the reciprocal reputation on cooperative decisions was more salient in the gain context than the loss context. Neurally, trial-wise parametric modulation analysis revealed two distinct neural systems that right anterior insula in the gain context and bilateral superior parietal lobule (SPL, including precuneus), left inferior parietal lobule (IPL), bilateral superior frontal gyrus (SFG), are positively correlated with partner’s reciprocal reputation. Based on the behavioral and neural results, we propose that individuals use a social heuristic preference-based mechanism in the gain context while involving more strategic or reasoning concerns in the loss context in processing others’ social reputation when making cooperative decisions in PGG. Furthermore, during the decision phase, cooperating with higher reputation individuals in the gain context increased the bilateral striatum activation, and the activation in the bilateral striatum function as a neural modulator of this effect only in the gain context. Finally, parametric modulation analysis using contribution as the modulator revealed the dorsal anterior cingulate context (dACC) in the gain context that suggested that the prefrontal cortex plays a vital role in computing the action values while making decisions in PGG. The current results contribute empirical evidence to our understanding of human cooperation from a new angle, through social interactions in a loss frame.
Children’s sunburn exposed: Identification of sun exposure and parental sun protection patterns
Authors: Thoonen Karlijn , Passos Valeria Lima , Schneider Francine , de Vries Hein , van Osch Liesbeth
Published: November 2020

2AbstractBackground: Preventing sunburn in childhood is imperative in the light of skin cancer prevention. To provide directions for targeted interventions, a better understanding of children’s sunburn and associated parental behaviours is necessary.Objective: To explore sun exposure and parent-for-child sun protection patterns and their relation with experienced sunburn in children.Materials & Methods: An online survey study was conducted among parents (n=1299) of children (4 to 12 years). Latent Class Analysis (LCA) was performed to identify parental subgroups in children’s sunburn, sun exposure and several sun protection behaviours (i.e. applying sunscreen, clothing, seeking shade) in two sun exposure settings (i.e. planned versus incidental). LCA results were validated by assessing predictions of class membership through several socio-demographic characteristics.Results: Reported sunburn in the previous year was frequent (>40%). Four latent classes of sunburn-exposure-protection were identified. Overall, the majority of parents reported fair sun protection behaviours. While lower protection behaviours were not strongly reflected in lower sunburn rates among the classes, high amounts of planned exposure (e.g. going to the beach) seemed to correspond with higher sunburn risk. Parents of younger children and those with more sensitive skin, reported sun protection measures more frequently. Older children and those with more sensitive skin experienced more sunburn.Conclusion: This study contributes to current insight in children’s sunburn, based on parent-proxy reports. Although a clear differentiation in sunburn risk was not found, several groups relevant for future interventions were indicated. By revealing the complexity of children’s sunburn, suggestions for further research are provided.
Cambridge Psycholinguistic Inventory of Christian Beliefs: A Registered Report of Construct Validity, Internal Consistency and Test-Retest Reliability
Authors: Clackson Kaili , Pohran Nadya , Galli Riccardo Mattia , Labno Laura , Farias Miguel , Bekinschtein Tristan , Noreika Valdas
Published: November 2020

While religious beliefs are typically studied using paper-based or online questionnaires and surveys, there are no standardized tools available for experimental studies of religious cognition. Here we present the first such tool - the Cambridge Psycholinguistic Inventory of Christian Beliefs (CPICB) - which consists of audio-recorded items of religious beliefs as well as items of three control conditions: moral beliefs, abstract scientific knowledge, and empirical everyday life knowledge. The CPICB is designed in such a way that the ultimate meaning of each sentence is revealed only by its final critical word, which enables precise measurement of reaction times and/or latencies of neurophysiological responses. Each statement comes in a pair of Agree/Disagree versions of critical words, which allows experimental contrasting between belief and disbelief conditions. Psycholinguistic and psychoacoustic matching between Agree/Disagree versions of sentences as well as across different categories of the CPICB items (Religious, Moral, Scientific, Everyday) enables a rigorous control of low-level psycholinguistic and psychoacoustic features while testing higher-level (dis)beliefs. In the exploratory Study 1 (N=20), we developed and tested a preliminary version of the CPICB that had 480 items. After selecting 400 items that yielded the most consistent responses, we carried out a confirmatory test-retest Study 2 (N=40). Pre-registered data analyses confirmed excellent construct validity, internal consistency and test-retest reliability of the CPICB religious (dis)belief statements. We conclude that the CPICB is suitable for studying Christian beliefs in an experimental setting involving behavioural and neuroimaging paradigms, and provide Open Access to the inventory items, fostering further development of the experimental research of religious cognition.
The Primary Pitfalls on the Road to Understanding Consciousness
Authors: Sipfle Karl
Published: November 2020

Consciousness and the human mind have been pondered for centuries. Today the most fundamental, likely outlines of the explanation of consciousness are known, and from this landscape we are well-positioned to fill in the basket of specific theories that will include the correct one. However, many errors in thinking and assumptions have accumulated, and even gained fashion, that obscure our progress. It is time to eliminate these, which we do herein by enumerating the complementary true assertions. Following that we mention four principles for choosing direction for further work. We conclude with a framework for further progress.
A conditional judgment procedure for probing evaluative conditioning effects in the absence of feelings of remembering
Authors: Stahl Christoph , Béna Jérémy , Aust Frederik , Mierop Adrien , Corneille Olivier
Published: December 2020

Attitude research has capitalized on evaluative conditioning procedures to gain insight into how evaluations are formed and may be changed. In evaluative conditioning, a conditioned stimulus (CS; e.g., an unfamiliar soda brand) is paired with an unconditioned stimulus (US) of affective value (e.g., a pleasant picture). Following this pairing, a change in CS liking may be observed (e.g., the soda brand is liked better). A question with far-reaching theoretical and practical implications is whether the change in CS liking is found when participants feel they do not remember the CS-US pairings at the time an evaluation is produced about the CS. Here, we introduce a new conditional judgment procedure - the two-button-sets (TBS) task - for probing evaluative conditioning effects without feelings of remembering about the valence of the US paired with the CS. In three experiments, the TBS is (1) is successfully validated; it is also used to (2) provide preliminary information on the feeling of remembering question, and (3) to examine an affect-consistent bias in memory judgments for CS-US pairings. Results do not support evaluative effects in the absence of feelings of remembering, and they oppose the view that affect-consistent bias is limited to memory uncertainty. We discuss these finding in light of previous evidence and of dual-learning models of attitudes. We also discuss limitations and research avenues related to the new procedure.
Transparent Communication About Negative Features of COVID-19 Vaccines Decreases Acceptance But Increases Trust
Authors: Petersen Michael Bang , Bor Alexander , Jørgensen Frederik Juhl , Lindholt Marie Fly
Published: November 2020

During the rapid development and rolling-out of vaccines against SARS-CoV-2, researchers have called for an approach of "radical transparency", where vaccine information is transparently disclosed to the public, even if negative information can decrease vaccine uptake. Consistent with theories about the psychology of conspiracy beliefs, these calls predict that a lack of transparency may reduce trust in health authorities and facilitate the spread of conspiracy theories, which may limit the long-term capabilities of health authorities during and after the pandemic. On the basis of pre-registered experiments conducted on large, representative samples of Americans and Danes (N > 13,000), the present study contrasts the effects of vague vaccine communication with transparent communication, which discloses either positive or negative vaccine features. The evidence demonstrates that transparent negative communication may indeed harm vaccine acceptance here and now but that it increases trust in health authorities. Furthermore, the alternative of vague, reassuring communication does not increase vaccine acceptance either and leads to both lower trust and higher endorsement of conspiracy theories.
Comment on: The association between early career informal mentorship in academic collaborations and junior author performance
Authors: Cebula Carla , Gauchotte-Lindsay Caroline , lido catherine , Mulvana Helen
Published: November 2020

This comment is written in response to the recent article published in Nature Communications (17th November 2020) entitled, ‘The association between early career informal mentorship in academic collaborations and junior author performance’ by AlShebli et al. This short paper provides a theoretical foundation based upon current literature to propose an alternative framework from which to conduct the analysis of the data collected by AlShebli et al. (2020).We believe that AlShebli et al’s (2020) results corroborate, at unique scale, the well-documented gender citation bias. We find that the interpretation of the data, that junior academic careers (both men and women) see greater career benefits when being mentored by senior men, is lacking theoretical foundation and not cognisant of the accepted knowledge on this topic. We are motivated in responding to this article by our concern that should this interpretation go unchallenged, we see a very high risk to the participation and progression of women in STEM academia.