bluuebunny/crossref_metadata_2025 huggingface dataset:
АНАЛІЗ РИЗИКІВ ІТ-ПРОЄКТУ ВЕБРЕСУРСУ ДЛЯ КОМУНІКАЦІЇ ОСВІТНІХ ЗАКЛАДІВ
Authors: ЖУРАН О.А. , ФОНАР Л.С. , КОНОВАЛОВ О.С. , ПАНІН В.О.
Published: November 2023

Метою дослідження є аналіз ризиків, пов’язаних із реалізацією ІТ‑проєкту адміністрування вебресурсів, призначеного для покращення комунікації між освітнім закладом і стейкхолдерами. Використання он-лайн соціальних мереж може спростити розповсюдження новин кафедри, здобутків здобувачів і викладачів, цікавих подій, пропозицій навчання, стажування, участі в конкурсах тощо. Створення сторінок у соціальних мережах дасть змогу структурному підрозділу допомогти випускникам залишатися в контакті, знаходити можливості співпраці, обмінюватися досвідом, а також організовувати зустрічі, заходи та спільні проекти в реальному житті. Основні причини невдач ІТ‑проєктів можуть включати таке: погане управління, недостатнє залучення зацікавлених сторін, недостатній аналіз вимог, зміни вимог під час розробки, недостатню комунікацію тощо. Усі ці фактори є ризиками щодо успішності реалізації проєкту й відповідності запланованим показникам за вартістю, часом, термінами або якості. Крім того, під час управління проєктними ризиками варто враховувати той фактор, що більшість ІТ‑проєктів унікальні, а іноді взагалі не мають аналогів. Саме тому й ризики для кожного з таких проєктів мають особливість. Важливо розглядати ризики ІТ‑проєкту вебресурсу для комунікації освітніх закладів, ураховуючи організаційні особливості й структурних підрозділів навчального закладу і властивості соцмереж та інтернет-спілкування, а також проблеми, які виникають у процесі використання сторонніх веб-ресурсів, на які виконавці не можуть впливати. У статті проведено комплексний огляд потенційних ризикових ситуацій, що можуть виникнути. Визначено 4 ризики внутрішнього й 4 ризики зовнішнього середовища проєкту. Для кожного ідентифікованого ризику з’ясовано причину його виникнення – фактор ризику. Найчастіше факторами ризику обраного проєкту є людські ресурси й форс-мажор. Підсумковий аналіз ризиків дає змогу розробникам, управлінцям і зацікавленим сторонам краще зрозуміти важливість аспектів безпеки та планування для успішної реалізації запропонованого ІТ‑проєкту з мінімізацією можливих негативних наслідків.
El presupuesto que no fue: retos en materia de rendición de cuentas. El caso del ramo defensa nacional
Authors:   Universidad Veracruzana, Guerra Osorno Irma del Carmen
Published: November 2023

El Presupuesto de Egresos de la Federación (PEF) constituye uno de los principales instrumentos de política pública en México para lograr los objetivos de desarrollo previamente establecidos por el gobierno en turno. Sin embargo, el Informe País 2020, sobre el Combate a la Corrupción en México (Merino et. al, 2022), identificó en el PEF distintas áreas en las que existe riesgo de captura debido a la opacidad y amplia discrecionalidad con la que pueden llegar a ejercerse los recursos. Una de estas áreas la constituyen las adecuaciones presupuestarias. Así, el objetivo de esta investigación es ampliar el alcance ...
Evaluación de resultados para el combate a la corrupción y la rendición de cuentas en los municipios, ante las limitaciones de la fiscalización al ejercicio de los recursos del FISM-DF
Authors:   Universidad Autónoma de Campeche, López Chan Oscar , Moguel Marín Susana Friné ,   Universidad Autónoma de Campeche
Published: November 2023

El propósito de este artículo es revisar los límites de la fiscalización de la Auditoría Superior de la Federación a los recursos del Fondo de Aportaciones para la Infraestructura Social Municipal (FISM-DF), ejercidos por los gobiernos municipales en México (2016-2021), para combatir la corrupción y fomentar la rendición de cuentas. Como acciones complementarias se propone evaluar los resultados en el cumplimiento del objeto social de la aplicación de tal fondo, que es la atención de la pobreza e implementar un sistema de indicadores anticorrupción, con precios de referencia para las obras, bienes y servicios pagados con el mismo.
The conundrum of corruption: reform for social justice
Authors:   Universidad de Guadalajara, Lugo Gutiérrez Damián Ignacio
Published: November 2023

El libro representa una mirada crítica a los postulados y las estrategias del paradigma dominante del combate a la corrupción, basado en una aproximación técnica y aséptica a los factores sociopolíticos que influyen en el origen y desarrollo del fenómeno.
Investigating lay perceptions of psychological measures: A registered report
Authors: Mason Joseph , Pownall Madeleine , Palmer Amy , Azevedo Flavio
Published: November 2023

In recent years, the reliability and validity of psychology measurement practices has been called into question, as part of an ongoing reappraisal of the robustness, reproducibility, and transparency of psychological research. While useful progress has been made, to date, the majority of discussions surrounding psychology’s measurement crisis have involved technical, quantitative investigations into the validity, reliability, and statistical robustness of psychological measures. This registered report offers a seldom-heard qualitative perspective on these ongoing debates, critically exploring members of the general public’s (i.e., non-experts) lay perceptions of widely used measures in psychology. Using a combination of cognitive interviews and a think aloud study protocol, participants (n = 23) completed one of three popular psychology measures. Participants reflected on each of the measures, discussed the contents, and provided perceptions of what the measures are designed to test. Coding of the think aloud protocols showed that participants across the measures had issues in interpreting and responding to items. Thematic analysis of the cognitive interviews identified three dominant themes that each relate to lay perceptions of psychology measurements. These were: (1) participants’ grappling with attempting to ‘capture their multiple selves’ in the questionnaires, (2) participants perceiving the questionnaire method as generally ‘missing nuance and richness’ and (3) exposing the ‘hidden labour of questionnaires’. These findings are discussed in the context of psychology’s measurement reform.
Influence of Plant Density and Application of Different NPK Doses on Growth and Yield Performances of Cucumber (Cucumis Sativus L.) under the Open Field Conditions in Kabul, Afghanistan
Authors:   Department of Horticulture, Agriculture Faculty, Badakhshan University, Afghanistan.  Email: sharafatullah2017@gmail.com, Omari Sharafatullah , Omerkhil Najibullah ,   Department of Forestry, Agriculture Faculty, Kunduz University, Afghanistan.  Email: n.omerkhilagr@gmail.com, Sadiq Gul Agha ,   Department of Horticulture, Agriculture Faculty, Kunduz University, Afghanistan.  Email: gulaghasadiq@gmail.com
Published: November 2023

The present study was conducted for one growing season from 12th March 2022 to 15th July 2022 in Horticulture Research Farm at Agriculture Faculty of Kabul University in open field, with the specific objective of finding out the interaction influence of three plant density and four NPK doses as a treatment on the growth and yield parameters of Nahid-F1 variety of cucumber. The experiment was laid out following the Factorial Randomized Block Design (FRBD), with three replications consisting of combined three level of plant geometry viz. 75×35 cm (S1), 75×45 cm (S2) and 75×55 cm and four doses of NPK viz., control (F0), 60:30:30 (F1), 80:40:40 (F2) and 120:60:60 (F3) as a treatment. The data on growth attributes and yield contributing characteristics of cucumber crop were recorded and analyzed trough SPSS (22) software (2011) using Analysis of Variance (ANOVA) for Factorial Randomized Black Design (FRBD). The results obtained from the current study reveal that all growth and yield characteristics under the study were remarkably influenced by plant density and dose of NPK and cucumber variety of Nahid-F1 performed better with T12 (75×55 cm + NPK 120:60:60), T8 (75×35 cm + NPK 120:60:60) and T3 (75×35 cm + NPK 80:40:40) in respect to the various growth and yield characteristics, such as number of branches, number of leaves per plant, plant height, stem girth, days to first flower bud initiation, days of first fruits picking, fruit length, fruit girth, average fresh fruit weight, number of fruits per plant, number of fruit per vine, yield per square meter and yield per hectare. While T1 (75×35 cm + control), T5 (75×45 cm + control) and T9 (75×55 cm + control) did not show any superiority in any growth and yield attributes as evaluated in Kabul agro-climatic region. Thus, T8 and T12 could be recommended to the farmers of Kabul province for better cucumber production in Kabul agro-climatic condition in Central Afghanistan.
Website Optimization and Analysis on XYZ Website using the Web Core Vital Method
Authors: Kristian Handoko Wijaya Sukardjoh  , Zahra Amalia
Published: November 2023

XYZ website is a business website that operates in the field of e-commerce which is implemented through websites and applications, for several years the website has had a percentage of users' usage speed which has decreased quite a bit and has become old, due to lack of maintenance of some of the features contained in the website application which have an impact on the lack of customer interest in buying goods on the XYZ website and more influential in terms of access from searching e-commerce notifications from Google that if the percentage of websites decreases over a long period of time, this will result in websites not being allowed to publish advertisements. In this study, we analyze the problem to understand the problem starting from small things, namely from the use of programming languages, the data provided, the use of writing code, third party or vendor support, filling out website content, and websites using vital core web architecture. So that the website used has good comfort, accelerates the use of the website which can be affected by the large number of customer visitors, and can facilitate the development team's performance in management and maintenance and provide many positive things from customers so that business runs fast and provides convenience for customers and the XYZ website can received by Google.
Klasifikasi Tingkat Risiko Kesehatan Ibu Hamil Menggunakan Algoritma Support Vectore Machine
Authors: Dzakwan Muhammad Dzakwan Ar Rosyid , Subektiningsih
Published: November 2023

Memprediksi apakah ibu hamil memiliki resiko tingkat kematian tinggi, sedang atau rendah. Metode yang digunakan adalah metode kuantitatif dengan menggunakan algoritma klasifikasi support vector machine (SVM) untuk mengetahui tingkat resiko kesehatan pada ibu hamil. Dengan menggunakan algoritma klasifikasi support vector machine(SVM) dapat memprediksi ibu hamil beresiko terkena penyakit atau tidak. Tingkat akurasi data sebelum dilakukan tahap preprocessing sebesar 60%. Setelah data memasuki tahap preprocesing, akurasi data yang didapatkan menjadi 71%. Hal tersebut terjadi karena pada dataset awal terdapat imbalance data. Setelah dilakukan preprocessing dan penyeimbangan data, kenaikan akurasi menjadi 11% lebih tinggi. Hasil dari penelitian ini, penelitian ini dapat membantu tenaga kesehatan dalam menekan angka kematian ibu hamil dengan mendeteksi secara dini tingkat resiko ibu hamil terkena suatu penyakit dengan parameter tertentu. Penelitian ini menggunakan dataset yang berasal dari UCI dataset. Dataste tersebut memiliki beberapa parameter seperti uisa, tekanan darah sistolik, diastolik BP, kadar glukosa, detak jantung dan parameter resiko. Dataset tersebut memiliki 1014 data
Implementasi Deep Classifier untuk Diagnosis Penyakit Glaukoma pada Citra Retina Mata
Authors: Dharmawan Dhimas Arief , Leuveano Raden Achmad Chairdino , Suryotomo Andiko Putro , Tahya Michel Pierce , Sani Sayang
Published: November 2023

Penerapan deep learning untuk diagnosis glaukoma dari gambar retina merupakan bidang yang berkembang pesat dalam pencitraan medis. Penelitian ini menyelidiki keampuhan model pembelajaran mendalam dengan menggunakan dua set data uji yang berbeda: DRISHTI-GS dan ORIGA, yang menjelaskan potensi dan tantangan dalam tugas medis yang kritis ini. Dalam kasus dataset DRISHTI-GS, model deep learning menunjukkan kinerja yang bervariasi di seluruh zaman. Epoch awal menunjukkan akurasi yang rendah dan kehilangan yang tinggi, tetapi peningkatan yang signifikan terjadi antara epoch 40 dan 70, mencapai akurasi sekitar 96% pada epoch 100. Hal ini menunjukkan potensi deep learning dalam mendiagnosis glaukoma dari gambar retina DRISHTI-GS. Sebaliknya, dataset ORIGA menunjukkan kemajuan yang lebih konsisten. Model ini terus meningkatkan akurasi, mencapai 97,54% pada epoch 80, dengan penurunan kerugian yang terjadi secara bersamaan, yang mengindikasikan konvergensi yang kuat. Hal ini menggarisbawahi kemahiran model dalam diagnosis dataset ORIGA, menyoroti janji klinisnya. Singkatnya, penelitian ini menunjukkan kelayakan deep learning untuk diagnosis glaukoma dari gambar retina, dengan hasil yang menjanjikan pada dataset DRISHTI-GS dan ORIGA.
Transformasi Pertanian Dalam Ruangan: Hidroponik Cerdas Berbasis IoT
Authors: Caniago Deosa Putra , Masril M Abrar
Published: November 2023

The growth of technology has had a significant impact on the agricultural sector, including the method of hydroponic cultivation. According to the Basic Health Research (Riskesdas) conducted by the Ministry of Health, 90% of the Indonesian population lacks sufficient vegetable consumption. The World Health Organization (WHO) recommends a daily vegetable intake of around 400 grams for adults, which can be fulfilled through indoor hydroponic gardens. However, hydroponic cultivation requires intensive monitoring and control, posing a challenge for busy urban communities. Therefore, one solution to address the challenges in hydroponic farming is leveraging Internet of Things (IoT) technology and utilizing Real-time Clock (RTC) to create a Smart Indoor Hydroponic Garden system that enables real-time control of water pH and room temperature using temperature sensors and water quality sensors. This system can be utilized by urban individuals who lack access to open land, allowing them to meet their daily vegetable needs directly from home.
Implementation of Deep Learning Using YOLOv7 and Telegram Notifications for Preventing Illegal Fishing in the Waters of Batam
Authors: Muhammad Abrar  , Deosa Putra Caniago
Published: November 2023

Batam Island is one of Indonesia's outermost islands that directly borders neighboring countries. The implementation of YOLOv7 to detect ships in the waters of Batam is capable of identifying ship objects, with test results after 100 training epochs producing a precision value of 1.00 and a confidence value of 0.882, indicating a high level of confidence in the detection results of the YOLOv7 model. The F1 score of 0.99 at a confidence level of 0.729 shows that this model achieves a high level of accuracy in object detection. Based on the evaluation results using a confusion matrix, it indicates high accuracy for each class in the YOLOv7 model: Ferry 93%, Indonesian Fishing Boat 85%, Malaysian Fishing Boat 89%, Thai Fishing Boat 91%, Vietnamese Fishing Boat 82%, Speedboat 94%, and Tanker 83%. The testing results of the website application integrated with YOLOv7 and Telegram bot produce a website that can detect objects and send notifications, thus expected to prevent illegal fishing.
Methodological approaches to assessing the impact of environmental factors on the efficiency of investments
Authors: N. M Shtefan , L. H Solianyk , A. M Honcharuk
Published: November 2023

Methods. The theoretical and methodological basis of scientific research was the work of scientists on the issues of evaluating the effectiveness of investments and improving the criteria for evaluating investment projects in accordance with today's challenges. In order to achieve the goal, the article uses general scientific and specific methods: methods of theoretical generalization – to study the process of improving the methods of assessing the economic efficiency of investments in accordance with changes in the environment and the development of scientific and technical progress; statistical methods – when determining the structure of capital investments; generalization and synthesis – to substantiate the scientific approach in improving the criteria for evaluating the economic efficiency of investments. Results. The article highlights issues related to the improvement of criteria for assessing the economic efficiency of investment projects in accordance with the requirements of modern economic conditions and the life of humanity as a whole, recommendations are provided in the field of taking into account the influence of environmental factors when determining the economic efficiency of investment projects. Novelty. The analysis of the structure of capital investments was carried out, the importance of the company's own funds for the implementation of investments was determined, while at the same time solving the question for the owner of the company about what would ensure obtaining a higher income: reinvestment of profit or rational use of dividends in private interests. The need to take into account the influence of environmental factors when determining the economic efficiency of investment projects is substantiated, for which it is necessary to define a toolkit for measuring environmental impact. When determining the economic efficiency of projects, it is proposed to take into account the environmental impact coefficient (EIC), which characterizes the ratio of economic damage to the environment after (DEa) and before the implementation of projects (DEb). Practical value. The results of the conducted research can be useful for business entities and investors who will participate in the post-war reconstruction of Ukraine.
Innovative activity in the basic metals industry: comparative analysis with EU countries
Authors: N. I Lytvynenko
Published: November 2023

Methods. In the process of studying innovation activities in the basic metals industry of Ukraine and European countries, methods of analysis and synthesis, empirical methods, induction and deduction techniques, graphical, logical and tabular methods were used. The methodological basis of the study was the methods of comparative analysis and observation, which made it possible to assess the current state of innovative activity in the basic metals industry of Ukraine. The graphical method made it possible to visualize the results of the study. Results. The use of comparative analysis made it possible to assess the current state of innovation activity in the basic metals industry of Ukraine in comparison with European countries. A comparative analysis, based on key indicators of innovation activities of industrial enterprises, was carried out. These indicators include the number of innovation activities of industrial enterprises; enterprise innovation expenditure of industrial enterprises; the number of introduced technological processes of industrial enterprises; the number of introduced innovative products (goods, services) of industrial enterprises; and total turnover from innovation activities of industrial enterprises. The analysis was carried out using public statistical data from the State Statistics Service of Ukraine and the statistical office of the European Union. It is revealed that innovation activities in metallurgical industry of Ukraine in terms of key indicators is significantly lower than in European countries. The main problems of functioning of the metallurgical industry of Ukraine are identified as part of the global industry. Novelty. There are proposed the main directions for improving innovation policy in the manufacture of basic metals to increase its competitiveness in the world market. Practical value consists in developing proposals to improve innovation policy in the basic metals industry. The results of the study can be applied for further research of innovation activities in metallurgical industry of Ukraine.
Artificial intelligence implementation in ukrainian banks: perspectives and limitations
Authors: V. V Solodkyi , Yu. A Polishchuk
Published: November 2023

Methods. During the research, the method of scientific abstraction was applied – to define the concept of «artificial intelligence»; analysis and synthesis – when identifying the functional capabilities of artificial intelligence; comparison – to determine the level of use of artificial intelligence systems in Ukrainian banks. Results. The article examines the genesis of algorithms of generative artificial intelligence (AI) from the point of view of the prerequisites for its appearance, development and impact on economic and financial agents. It was determined that artificial intelligence is the main factor in revitalizing economic growth and a strategic advantage in the long term. The current state of implementation of AI tools in the activities of Ukrainian banks in comparison with foreign banks is analyzed. For further development, commercial banks are suggested to create joint projects with scientific institutions, technological companies regarding training and adaptation of models for clients of financial institutions and parallel implementation of algorithms in internal bank processes, including search, adaptation and development of personnel, marketing, internal information technologies and processes or in the event of sufficient financial resources, the creation of intra-bank divisions for the development of AI. The transition to innovative types of services will also require financial institutions to communicate properly with clients. Novelty. The level of use of artificial intelligence systems in Ukrainian banks was determined. According to the results of the study, it was determined that the key factor that negatively affects the introduction of new technologies is the high cost of investments in the preparation of models and the selection of teams. Other challenges relate to the regulation of relations with consumers of financial services and insufficient attention from the regulator. Practical value. Applied research results are focused on taking into account the specific positions and opportunities of the enterprise's competitive potential when evaluating the effectiveness of its innovative activities.
Scenario forecasting of changes in the state of Ukrainian steel plants in the conditions of war on the basis of probabilistic methods
Authors: V. Ya Shvets , H. V Baranets , D. O Hrebenko
Published: November 2023

Methods. The results were obtained through the use of the following methods: systematic and comparative analysis – when determining changes in the composition of external factors influencing the activity of metallurgical enterprises in wartime conditions; abstraction – when determining the adjusted probability of the development of events under each scenario; modeling – when constructing a posteriori probabilities of the realization of scenarios of changes in the status of metallurgical enterprises of Ukraine. Results. The possibility of using probabilistic methods in the developed model of scenario forecasting of changes in the state of industrial enterprises in wartime is substantiated. The Bayesian method allows to quantify the probability of implementation of each scenario. Based on the study of the factors influencing the activities of steel plants in the first half of 2023, the scenario forecasting model is corrected in the forecast estimates of the performance of individual indicators. Taking into account the direction of changes in the indicators, the corrected probability of events under each scenario was determined. The a posteriori probabilities of realization of the scenarios of changes in the state of steel plants of Ukraine are calculated using the Bayes formula. Novelty. A scientific and methodological approach to scenario forecasting of changes in the state of steel enterprises in wartime conditions is developed based on the use of probabilistic modeling methods, in particular the Bayesian method. Practical value. The obtained results of the scenario forecasting of changes in the state of steel enterprises of Ukraine in the conditions of war, which are supplemented by determining the probability of implementation of each scenario based on the calculation of a posteriori probability using the Bayesian method, allow managers of steel enterprises to develop programs of recovery from the crisis caused by military aggression and its consequences, taking into account the most likely scenario of events.
Evaluation of the enterprise's life cycle by phases of viability as a basis for building cluster polyvector models of development transparency
Authors: V. V Prokhorova , A. S Zaitseva
Published: November 2023

Methods. In the process of tracing the life cycle of industrial enterprises through the phases of life, methods of analysis and synthesis, empirical methods, methods of induction and deduction, graphical and logical methods, and the method of analysis have been used, as well as scientificeconomic and statistical analysis. The methodological basis of the research is the index method, the results of which allow us to evaluate the life cycle of enterprises according to the phases of life cycle, which is the basis of cluster polyvector models of development transparency. Results. The article improves the structural and functional model of building an integrated adaptive-relevant system for evaluating the life cycle of an enterprise by phases of viability, which synthesizes a complex system of executing tactical actions, is implemented on the basis of receiving information from the object's local phases of the enterprise's viability, performs the functions of recognition and identification compatibility of phases of viability with the level of development of the enterprise, which allows industrial enterprises to achieve the maximum permissible level of transparency of development under the condition of effective formation of cluster polyvector models for the purpose of forecasting and eliminating discrepancies in goals and strategic directions of development management, forming the concept of viability of industrial enterprises. Novelty. It consists in improving the scientific and methodological foundations of the development of a structural-functional model of an integrated adaptive-relevant system for evaluating the life cycle of an enterprise by phases of viability. Practical value. Assessing the life cycle of an enterprise by phases of viability as a basis for building cluster polyvector models of transparency of development allows to form a system of parameterization of its activity, which is an analytical tool to organize vertical and horizontal connections of a multi-level and multifunctional management decision-making system, taking into account the properties of interdependent influence and establishing critical points for the most significant security parameters of individual trajectories of transparent development.
The Development of Dry Extract Technology from Callus Culture Biomass of Scutellaria baicalensis
Authors: Danilova A. A. , Pivovarova N. S. , Flisyuk E. V.
Published: November 2023

Introduction. Plant biologically active substances (BAS) are valuable for drug development in view of their pharmacological effects and metabolic proximity to the human body. As an example of a useful herbal raw material, the roots of Scutellaria baicalensis, which contain species-specific flavonoids, baicalin and scutellarin, possess the potency of creating antiviral drugs and functional nutrition systems with antioxidant and adaptogenic properties. In order to levelling the existing limitations of using intact plant in pharmaceutical practice, we proposed a nature-saving and ergonomic approach of cultivation of S. baicalensis cells under in vitro conditions. This technology allows to extract active substances of S. baicalensis without causing damage to the environment and contributes to the reduction of the time required to produce the necessary amount of plant material with an increase in the efficiency of production processes.

Aim. The development of dry extract technology from S. baicalensis callus biomass.

Materials and methods. The object of the study – biomass of S. baicalensis cells obtained from callus culture. Functional characteristics (friability, Hausner’s coefficient, Carr’s index, fractional composition, as well as porosity and hygroscopicity) of S. baicalensis biomass and dry extract on its basis were determined according to the methods of the EAEU Pharmacopoeia. Extraction of plant material was carried out by maceration method with heating in a water bath with reflux condenser. Qualitative and quantitative analysis of BAS in the dry extract was carried out by spectrophotometry and high-performance liquid chromatography. Quality indicators and functional characteristics of the finished product were evaluated in accordance with pharmacopeial requirements.

Results and discussion. The functional characteristics of the S. baicalensis biomass were evaluated and the possibility of obtaining a dry extract on its basis was confirmed. We selected parameters of BAS extraction process, established the presence of baicalin in the biomass extract and carried out a comparative evaluation of aglycone profile in the extract based on callus culture and roots of intact plant. The properties of the finished product were evaluated for compliance with regulatory requirements, as well as technological characteristics.

Conclusion. The quality indicators of the dry extract of the S. baicalensis biomass satisfy the normative conditions. The technological characteristics of dry extract are suitable for the utilisation as a phytosubstance for the development of medicines of combined type and dietary supplements.
Evaluation of the α2-adrenergic Agonist Mafedine Effects on White Outbred Mouse Behaviour Following Acute Administration
Authors: Kurmazov N. S. , Chervonetskiy S. A. , Prikhodko V. A. , Sysoev Yu. I. , Okovityi S. V.
Published: November 2023

Introduction. α2-adrenergic agonists are not only used as antihypertensive and sedative agents, but are also of interest as potential medications for the treatment of neurological disorders. Previous research has shown a compound from this class, 6-oxo-1-phenyl-2-(phenylamino)-1,6-dihydropyrimidine-4-ol (mafedine), to exert strong neuroprotection under experimental conditions. Despite its long record of development, the effects of mafedine on animal behavioural characteristics remain unknown.

Aim. This work was aimed at evaluating the effects of mafedine sodium at three doses (1, 10, or 50 mg/kg) on white outbred mouse behavior in three tests: Open Field, Elevated Plus Maze, and Light/Dark Box.

Materials and methods. Experiments were carried out on 60 white outbred male mice weighing 20–22 g, randomized into 4 groups (n = 15): 1) control (0,9 % saline); 2) mafedine (1 mg/kg); 3) mafedine (10 mg/kg); 4) mafedine (50 mg/kg). All agents were administered via single intraperitoneal injections 20 min before testing. Animal behavior was assessed using the Open Field, Elevated Plus Maze, and Light/Dark Box tests following conventional protocols with group reassignment between tests and an inter-test time interval of at least 2 days. Statistical analysis was carried out using the Prism 8.0.2 software package.

Results and discussion. At 1 or 10 mg/kg, mafedine did not affect animal behaviour in either of the tests. At 50 mg/kg, it produced an anxiolytic effect, as indicated by the decrease in the anxiety index values for the Elevated Plus Maze test as well as the increase in peeking out frequency in the Light/Dark Box test, compared to respective control values.

Сonclusion. Mafedine sodium salt at doses between 1 and 50 mg/kg was shown to produce no adverse effect on mouse behaviour, indicating a good safety profile of the compound. The discovered anxiolytic effect of mafedine at the highest dose validates its further research not only as a neuroprotector, but also as an anti-anxiety agent.
Pelatihan Pembuatan Media Pembelajaran Berbasis Website Terintegrasi Model Pembelajaran Project Based Learning bagi Guru SMAN 2 Tondano Minahasa
Authors: Kamaruddin Kamaruddin , Silangen Patricia Mardiana , Tulandi Djeli Alvi
Published: November 2023

This community service aims to increase knowledge and competence in creating website-based learning media integrated with the project-based learning (PjBL) learning model for teachers at SMAN 2 Tondano, Minahasa Regency. Implementing this service used training, which included lectures, discussions, simulations, and mentoring. The activity evaluation instrument used a questionnaire and was analyzed descriptively. The results of this service showed that the ability of ICT teachers at SMAN 2 Tondano increased in creating website-based learning media integrated with the PjBL model. The implementation of training and mentoring activities received a positive response from participants, as evidenced by the enthusiasm and activeness of teachers in participating in the training. The evaluation results showed that the level of satisfaction and increase in teacher knowledge after participating in the training was in the very good category. Teachers were very interested in using website-based learning media because of its advantages and integration with the PjBL learning model.
Pemberdayaan Masyarakat Berbasis Lingkungan Melalui Penataan Lahan Kosong untuk Apotik Hidup di Hutan Kota Giong Siu Mataram
Authors: Jannah Husnul , Desimal Iwan , Erista Nita , Harisanti Baiq Muli , Nurtajudin Nurtajudin , Primawati Sri Nopita
Published: November 2023

This service aims to empower the community around the Giong Siu City Forest, both visitors and managers, by arranging empty land for a live dispensary. The method of implementing this service included socialization and practice with a participatory approach. The results of this service activity showed that visitors and managers were very enthusiastic about participating in the socialization activity until completion. Medicinal plant planting activities were carried out together with the manager. Medicinal plants planted include yellow turmeric, white turmeric, ginger, galangal, galangal, aloe vera, and lavender. This planting was carried out in the Giong Siu location, which was still empty, so that optimal light was obtained and was close to a water source for watering.
Barriers to Lifestyle Modification Compliance among Type 2 Diabetic Patients in Lesotho
Authors: Malefu Ts’osane , Mahlelehlele Bokang Amelia , Murandu Moses
Published: November 2023

Diabetes mellitus (DM) has been considered a serious long-term condition which is one of the top 10 causes of death among adults and it has got a major impact on lives and well-being of individuals, families and societies. The most common type of DM in Africa is Type2 (T2DM). Diabetes being a major problem worldwide, healthy eating coupled with regular physical activity help in achieving a good glycemic control as well as delaying and reducing the onset of commonest diabetes complications. The current study aimed at exploring the barrier to lifestyle modification compliance among type 2 diabetic clients at Paki health center Lesotho. In this study, a quantitative descriptive design was applied in exploring the barriers of compliance to lifestyle modifications (diabetes self- management) among adults with type 2 diabetes. Data was collected using semi-structured questionnaires, which were administered to 40 study participants who were purposively selected for inclusion into study. The study revealed that among other factors, financial constraints 21participants (52.5%) is associated with non- compliance to healthy eating habits. Other reasons from non-compliance to healthy eating were identified as absence of written instructions, sickness, lack of stamina to exercise, laziness and lack of access to physical activity facilities with percentages 85%, 65%, 50% and 40% respectively. Thus, study findings reveal needs for continuous health education on health benefits of healthy eating habits and physical activity.
Provider Awareness of Postpartum Hemorrhage Risk Assessment Tool at the Time of Admission at a Community Setting
Authors: Agbo Kimberley , Chong Woojin
Published: November 2023

Objectives: The primary objective of this study was to determine the provider's awareness of the postpartum hemorrhage risk assessment tool at the time of admission. In addition, in keeping with the organization’s continual performance improvement philosophy, education on postpartum hemorrhage risk was provided to survey respondents who self-reported that they were unaware or requested additional resources. Methods: This cross-sectional study utilized an anonymous survey methodology. We distributed a postpartum hemorrhage awareness risk assessment questionnaire and collected participant responses without personal identifiers over a 3 month time period, January 2023 – March 2023. Analysis was completed using Fischer’s exact test. Alpha level was set to 0.05. Results: 39 participants completed the questionnaire attending physicians: n=10 (25.6%), nursing staff: n=15 (38.5%), and resident physicians: n=14 (35.9%). 7 of the 10 attending physicians (70%) and 9 of the 15 nursing staff (60%) have worked over 10 years in their profession, while 11 of the 14 resident physicians (78.6%) have worked in their profession for 1-5 years (p=<0.0001). 5 of the 10 attending physicians (50%) and 7 of 15 nursing staff (46.7%) were 36-50 years old, while 13 of 14 resident physicians (93%) were 25- 36 years old (p=<0.0001). Majority of the participants were White; 5 attending physicians (50%), 11 nursing staff (73.3%), and 9 resident physicians (64.3%). Nursing staff had the most awareness of the postpartum hemorrhage awareness risk assessment tool at the time of admission (100%) in comparison with attending physicians (50%) and resident physicians (64.3%), (p=0.005). Nursing staff had the most knowledge of where to access the assessment (93.3%) in comparison to attending physicians (10%) and resident physicians (0%), (p=<0.0001). Conclusions: Our study revealed a statistically significant difference in awareness of the postpartum hemorrhage risk assessment tool at the time of admission amongst the 3 groups of providers; attending physicians, nursing staff, and resident physicians. The nursing staff had the most awareness in comparison with other providers. The data also highlighted the inconsistencies with accessing the risk assessment and with communication of information obtained through the assessment among providers. A quality improvement project should involve notifying providers of patients that are stratified to high risk, developing a simpler method for all providers to readily access the risk assessment tool, and increasing preparedness by creating an algorithm or bundle.
Permanent Education for Health Professionals during COVID-19: Scoping Review
Authors: Lemos Isabelle Lima , Borgmann Ariela Victoria , Motta Andressa Becker , Nogueira Bianca Soares , Jaworski Amanda Freschi , Trindade dos Santos Tatheanne da Silva , Fumagalli Gisele Tomazinho , Ribeiro Elaine Rossi
Published: November 2023

Background: The pandemic of COVID-19 was declared by the World Health Organization on March 11, 2020. With this, the world had to adapt to a new way of carrying out permanent health education. The objective was to map what the national and international literature currently has to say about how continuing education is being provided to health professionals in the context of the COVID-19 pandemic. Methodology: This is a scoping review, thus, the PRISMA-ScR guidelines were used for its elaboration. The search was performed in several stages, by four independent reviewers, following the criteria of the Joanna Briggs Institute (JBI), in the following databases: PubMed, Science Direct, LILACS and MEDLINE (via BVS). The descriptors used were "Continuing Education", "health" and "COVID-19". Results: Ten articles dealing with the proposed theme were included and analyzed in this review. The year of publication ranged from 2020 to 2021. Six articles were conducted in Brazil, one in Poland, one in China and one in Canada. Five of them were in Portuguese and five in English. Nine studies are descriptive experience reports and one theoretical-descriptive study of actions performed to promote HPS. The most prevalent research site was the Brazilian Basic Health Units (BHU), but it also occurred in tertiary hospitals. It was possible to identify several measures for continuing education in Brazil and worldwide during the COVID-19 pandemic. Conclusion: The strategies employed were effective and produced a positive impact on the communities employed. We encourage actions like those presented to be carried out within health services, within the reality and singularity of each place, in order to provide updates and continuity of education in health.
Legal Developments On The Use Of Protected Forest Areas For Geothermal Power
Authors: Nugrahani Dian
Published: November 2023

The latest developments related to indirect Geothermal utilization in conservation areas in connection with the issuance of Law Number 11 of 2020 concerning Job Creation, which includes the forestry sector and its amendments through Government Regulation in Lieu of Law Number 2 of 2022 concerning Job Creation. The creation of the facilities provided by the Government can positively impact the ease of Geothermal utilization. The research method used is a normative juridical method. The method of data analysis in this study was carried out qualitatively by elaborating and analyzing various secondary data and legal materials obtained in order to answer each of the problem formulations. Conservation forest areas in the Sumatra region have many animals that must be preserved. Geothermal utilization is required to follow specific standards and norms by not damaging the landscape area of forest areas.
Benthic fauna along sandy beaches enriched by metals after mining disaster
Authors: Brahim S , Sobrinho TG , Albino J , Zanetti G , Amaral VS , Carneiro MTWD , Souza JR , Castro LB , Muehe D , Souza BS , Brandão GP , Krause M , Oliveira LHS , Coelho UP , Silva EE , Silva IJ , Neves JA , Paiva-Tagliari D , Costa KG
Published: November 2023

In 2015, 60 million tons of ore tailings from the Fundão dam failure entered the Doce River basin, Brazil, and reached surrounding sandy beaches. This study evaluated the influence of sedimentology and morphology of beaches that received mining tailings on chemical element concentrations and consequent benthic community responses. We collected sediments for physical (granulometry, heavy mineral, and calcium carbonate content) and geochemical (chemical elements) analyses and biological diversity parameters (benthic macro- and meiofauna density, richness, and composition) on 8 beaches with different morphodynamic types. Beaches with more dissipative characteristics retained the highest contents of mud, As, Fe, Mn, V, and heavy minerals, present in the tailings. We also recorded the lowest density and richness of macrofauna on these beaches, compared to more reflective beaches. These results contradict the global trend, suggesting that anthropic disturbances outweigh the effects of morphodynamics in structuring the benthic fauna community, mainly in dissipative sandy beaches.
Az onkológiai biológiai kezelések és a magas vérnyomás kapcsolatának elemzése
Authors: Harisi Revekka
Published: November 2023

A biológiai gyógyszerekkel kombinált kemoterápia valódi áttörést jelent a lokálisan előrehaladott és metasztatikus daganatos betegek hatékony kezelésében. Az angiogenezis-gátlás egyik leggyakoribb és klinikailag jelentős mellékhatása a magas vérnyomás kialakulása. Az összefoglaló cikknek az a célja, hogy elemezze a vascularis endothelialis növekedési faktor jelátviteli útvonal gátlói és a magas vérnyomás közötti kapcsolatot. Áttekintjük a VEGF/VEGFR gátlók által kiváltott magas vérnyomás előfordulását, kialakulásának mechanizmusait, a vérnyomásértékek rendszeres ellenőrzésének fontosságát, a lehetséges kezelési stratégiákat és a profilaktikus vérnyomáscsökkentő kezelés hatékonyságát. Összehasonlítjuk a klinikai vizsgálatok eredményeit, hogy tisztázzuk az antiangiogén-kezelés során bekövetkező vérnyomás-emelkedés prognosztikai és prediktív jelentőségét. A biológiai kezelés és a magas vérnyomás közötti kapcsolat további kutatása hatékonyabb, hosszabb túléléssel és jobb életminőséggel járó kezelést eredményezhet az előrehaladott daganatos betegekben.
TÜRKİYE İNSAN HAKLARI VE EŞİTLİK KURULUNUN İDARİ PARA CEZASI KARARLARINA KARŞI YARGI YOLU
Authors: Alyanak Servet
Published: November 2023

6701 sayılı Türkiye İnsan Hakları ve Eşitlik Kurumu Kanunu’nun 1. maddesiyle, “insan onurunu temel alarak insan haklarının korunması ve geliştirilmesi, kişilerin eşit muamele görme hakkının güvence altına alınması, hukuken tanınmış hak ve hürriyetlerden yararlanmada ayrımcılığın önlenmesi ile bu ilkeler doğrultusunda faaliyet göstermek üzere” Türkiye İnsan Hakları ve Eşitlik Kurumunun kurulduğu belirtilmiştir. Makalede, Türkiye İnsan Hakları ve Eşitlik Kurulunun idari yaptırım (para cezaları) kararlarına karşı yasa yolu ve merciine ilişkin karşılaşılan sorunlara değinilmiştir. Makalede öncelikle TİHEK’in genel olarak görev alanları ve ayrımcılık yasağı ihlallerine karşı aldığı idari yaptırım kararları (para cezaları) hakkındaki konuya ilişkin ilgili mevzuatı ortaya konulmuştur. Konuyla ilgili TİHEK’in ayrımcılık yasağını ihlal eden kişiler aleyhine aldığı kararlar ve bu kararlara karşı yapılan başvuru üzerine idari yargı ve adli yargı mahkemelerince alınan kararlar çerçevesinde değerlendirme de yapılmıştır.
Ecological-economic issues of modern horticulture and their solutions
Authors: Bendasiuk O. , Almashiy Ya.
Published: November 2023

In the article, the main risks of gardening are identified, which are associated with natural and climatic conditions and the slow pace of intensification of the gardening industry. Factors that hinder the development of the gardening industry are revealed, including: violation of economic principles of organizing expanded reproduction; lack of domestic production of mechanization, automation and chemicalization means, insufficient qualification level of specialists. The directions of development of gardening are defined, which provide for the transition to an intensive way of growing gardens and the production of planting material of new quality, close in its parameters to countries with developed gardening. The use of various chemical protection agents and the increase in the yield of fruit and berry crops require the adoption of urgent ecological stabilization measures.
Jumlah Kunjungan Posyandu Terhadap Status Gizi Balita di Posyandu Nagari Balingka Kabupaten Agam
Authors: Febria Chyka , Rusdi Pagdya Haninda Nusantri , Nugrahmi Mega Ade
Published: November 2023

Posyandu adalah pintu masuk dalam layanan kesehatan seperti imunisasi, mendeteksi dan stimulasi pertumbuhan dan perkembangan anak yang tujuan agar penurunan AKB menurun dengan cepat. Rendahnya kunjungan posyandu bisa dampak buruk terutama pada kebutuhan gizi anak. Berdasarkan data dari kabupaten Agam pada tahun 2019 bahwa jumlah cakupan kunjungan balita dari 23 Puskesmas yang ada, kurang dari 50% kunjungan posyandu balita nya. Tujuan penelitian ini adalah untuk mengetahui hubungan jumlah kunjungan posyandu terhadap status gizi balita. Penelitian ini dilaksanakan pada bulan Oktober 2023 di Nagari Balingka dengan jumlah sampel 53 sampel dengan menggunakan Teknik proporsional random sampling. Hasil penelitian didapatkan mayoritas umur anak berada pada rentang 37- 48 bulan sebanyak 32 orang (60,3%). Responden jenis kelamin anak mayoritas perempuan sebanyak 27 orang (51%) dengan umur ibu mayoritas antara 17-25 tahun sejumlah 30 (56,6%). Responden ibu mayoritas berpendidikan SMA sebanyak 21 orang (39,6%) dengan status gizi anak mayoritas kurang berjumlah 31 anak (58,4%). Bahwa responden ibu yang kunjungan posyandu tidak rutin dengan gizi kurang sebanyak 24 anak (77,4%), dan kunjungan posyandunya rutin dengan gizi kurang sebanyak 7 anak (22,5%). Hasil uji statistik didapatkan P value 0,03 maka Ho ditolak sehingga bisa disimpulkan bahwa ada hubungan jumlah kunjungan posyandu dengan status gizi balita.