bluuebunny/crossref_metadata_2025 huggingface dataset:
Regulators of Intestinal Epithelial Migration in Sepsis
Authors: Meng Mei , Klingensmith Nathan J. , Liang Zhe , Lyons John D. , Fay Katherine T. , Chen Ching-wen , Ford Mandy L. , Coopersmith Craig M.
Published: February 2018

The gut is a continuously renewing organ, with cell proliferation, migration, and death occurring rapidly under basal conditions. As the impact of critical illness on cell movement from crypt base to villus tip is poorly understood, the purpose of this study was to determine how sepsis alters enterocyte migration. Wild-type, transgenic, and knockout mice were injected with 5-bromo-2’deoxyuridine (BrdU) to label cells in S-phase before and after the onset of cecal ligation and puncture and were sacrificed at predetermined endpoints to determine distance proliferating cells migrated up the crypt–villus unit. Enterocyte migration rate was decreased from 24 to 96 h after sepsis. BrdU was not detectable on villi 6 days after sham laparotomy, meaning all cells had migrated the length of the gut and been exfoliated into its lumen. However, BrdU positive cells were detectable on villi 10 days after sepsis. Multiple components of gut integrity altered enterocyte migration. Sepsis decreased crypt proliferation, which further slowed enterocyte transit as mice injected with BrdU after the onset of sepsis (decreased proliferation) had slower migration than mice injected with BrdU before the onset of sepsis (normal proliferation). Decreasing intestinal apoptosis via gut-specific overexpression of Bcl-2 prevented sepsis-induced slowing of enterocyte migration. In contrast, worsened intestinal hyperpermeability by genetic deletion of JAM-A increased enterocyte migration. Sepsis therefore significantly slows enterocyte migration, and intestinal proliferation, apoptosis and permeability all affect migration time, which can potentially be targeted both genetically and pharmacologically.
Survey of Core Trainees’ Confidence in Electroconvulsive Therapy
Authors: Scott Gillian , Semple David M.
Published: February 2018

Objectives

The objective of the survey was to assess confidence in electroconvulsive therapy (ECT) in core psychiatry trainees across Scotland, looking at both theoretical and practical aspects of ECT.

Methods

A link to a 14-item electronic questionnaire was distributed to core trainees via deanery administrators. Most questions were based on the Royal College of Psychiatry's ECT guidelines.

Results

A total of 85 responses were analyzed from trainees at all 3 levels of core training and from all health boards across Scotland. Almost 90% of trainees felt that their ECT training was sufficient, with more senior trainees rating their training better than those in the first year of training. Trainees who had theoretical teaching before their practical sessions rated their training better than those with purely observational training. Most trainees felt confident delivering ECT under supervision, and nearly 75% of trainees felt confident preparing a patient for ECT. The areas in which trainees felt least confident were in practical aspects such as dosing protocols and electroencephalogram interpretation.

Conclusions

While ECT training and trainee confidence in delivering ECT were generally good, there are variations in trainees' experience that could be addressed by having a standardized ECT training, including theoretical teaching and practical competencies, in line with current guidelines. Ideally, evidence of meeting the Royal College recommendations for ECT competencies could be made a compulsory aspect of core training in the United Kingdom.
A 6-Year Follow-up Study of Vagus Nerve Stimulation Effect on Quality of Life in Treatment-Resistant Depression
Authors: Trottier-Duclos François , Desbeaumes Jodoin Véronique , Fournier-Gosselin Marie-Pierre , Richer François , Desjardins Nathalie , Tieu Sylvie , Lespérance Paul
Published: February 2018

Objectives

Treatment-resistant depression (TRD) carries a major burden on those affected by this disease and significantly impacts their quality of life (QOL). Vagus nerve stimulation (VNS) has showed promising results on symptoms, but its impact on QOL remains underresearched. This study aims to evaluate the long-term effects of VNS on both QOL and clinical symptoms for TRD patients, through a naturalistic 6-year follow-up.

Method

Outpatients with confirmed TRD were enrolled to receive VNS. None of the patients enrolled left the study or was lost at follow-up. Patients were evaluated at 1, 3, 6, 12, 24, 36, 48, 60, and 72 months for a total of 10 assessments using the 36 item Short Form questionnaire, Hamilton Rating Scale for Depression and Hamilton Anxiety Rating Scale.

Results

Ten patients were enrolled with a mean age of 50 years. This study shows a clinically and statistically significant improvement of the mental QOL (P = 0.012), physical QOL (P < 0.002), depressive symptoms (P < 0.001), and anxiety symptoms (P < 0.001).

Conclusions

This long-term naturalistic study is the first to demonstrate that the therapeutic effect of VNS on TRD goes beyond clinical symptoms to improve the daily QOL of those affected.
Integration of EBSCO Discovery Service widget into the learning spaces of LMS
Authors: Chew Bee Leng , Rahim Marnisya Abdul , Vighnarajah Vighnarajah
Published: February 2018

Purpose

Recent advancement in technological development has encouraged distance learning institutions to be more productive and creative in effectively utilizing the Learning Management System (LMS). Among the many measures employed is the integration of federated search engine into the LMS which allows for a more productive and wider scope of information retrieval through the provisions of library resources and services. The purpose of this paper is to report one such case study in Wawasan Open University exploring the integration of federated search engine (EBSCO Discovery Service (EDS) widget) into the learning spaces of LMS. Widgets resemble apps that enable the integration of EDS functionality in providing access for students to retrieve library learning resources from the convenience of the LMS, excluding the need to log onto the library.

Design/methodology/approach

This paper presents a discussion that highlights the development and conjectural implementation of a framework on the integration of the EDS widget into the University’s LMS. Data collection includes meta-analysis data from the micro- and macro-level infrastructure that make up the framework, namely, end-user layer, system layer and data management layer.

Findings

Findings from this study addressed significant importance to the library in promoting effective search and utilization of information needs. The findings will also make clear recommendations in developing effective collaborations between the library and faculties. Although the implementation of this framework is still in a developmental stage, this study still provides pertinent information in validating the integration of EDS into the University’s LMS.

Research limitations/implications

While serious limitations are not anticipated, possible concerns do exist with programming algorithms in the integration of EDS into the LMS. These challenges will be reported in the paper as reference for future replications of study

Practical implications

One key implication is the increase in the usage of the library resources and the potential to reach a larger audience of remote library users.

Originality/value

The primary advantage is to minimize the need for multiple gateway login while ensuring the library to monitor relevant library databases activities throughout the system check of the LMS.
The behavioural intention to use video lecture in an ODL institution
Authors: Chiam Chooi Chea , Woo Tai Kwan , Chung Han Tek , K.P. Nair P. Rajesh Kumar
Published: February 2018

Purpose

The purpose of this paper is to gain insight into learners’ behavioural intention to use the video lectures as their learning material. The behavioural intention construct is measured in terms of perceived ease of use and perceived usefulness of video lectures. It is hoped that the findings of this study will provide feedback as to learners’ intention to use as well as guidelines on how to improve the development of video lectures as the university gears to offer more courses in the fully online mode in the near future.

Design/methodology/approach

A total sample of 392 questionnaires were collected for this study using technology acceptance model model. Descriptive and inferential statistics are used as the main analytical tool to study the learners’ behavioural intention to use the video lectures as their learning material. The behavioural intention construct is measured in terms of two dimensions: perceived ease of use and perceived usefulness of video lectures.

Findings

In conclusion, the findings from this research study seem to suggest that OUM learners have a positive perception of video lectures with reference to the two dimensions of “ease of use” and “usefulness”, where ease of use is concerned, OUM learners rate content relevancy, appropriate language and viewing flexibility as the strongest points of video lectures. The aspects ranked lowest are technical (ability to play the video lecture smoothly from the beginning to the end) as well as objective of usage (video lectures are not rated high as revision material for exam preparation).

Research limitations/implications

Future studies can be conducted pertaining to issues on the context in which learning is taking place within higher education, various definitions of video, and ways of categorising and presenting these different types, teaching “with” and “through” video from the perspective of the lecturer and the educational institution, approaches to didactically embedding and integrating video into a course that results in effective learning and the process and support needed by the (traditional) lecturer to create and deploy various types of video content.

Originality/value

Over the last ten years, the production of video has gone from a complicated and technical process to one easily done by the general masses. It is now possible for anyone with a mobile phone to make a video recording. The question lies on whether the students have deeper meaning of learning via video lectures and the perception of students on using video lecture as teaching tool in the open and distance learning.
An empirical framework for mainstreaming OER in an academic institution
Authors: Abeywardena Ishan Sudeera
Published: February 2018

Purpose

There is immense potential in open educational resources (OER) for encouraging systemic change within academic institutions toward increasing access and equity in education. The purpose of this paper is to propose an empirical framework and a checklist for mainstreaming OER in an academic institution.

Design/methodology/approach

The empirical framework and the mainstreaming checklist is formulated based on an extensive review of literature and case studies strengthened by the author’s personal experience as an academic, researcher, practitioner, policymaker and international development expert in the field of OER.

Findings

The proposed empirical framework and OER mainstreaming checklist identifies several processes to be completed by key stakeholders for successful mainstreaming of OER in an academic institution.

Practical implications

The proposed framework assumes that the institution which is undergoing mainstreaming of OER follows the principles of outcomes-based education and that it has an established mechanism for measuring the mastery of learning outcomes and the role of OER in accreditation.

Originality/value

One key feature of the framework is its horizontal structure where stakeholders take a team-based approach to completing the required tasks for mainstreaming OER. This, in turn, increases ownership of the mainstreaming process leading to higher success rates and sustainability. Second, the mainstreaming checklist breaks down each process into several achievable tasks and assigns them to the relevant team. Third, the framework supports continuous quality improvement which encourages institutions to periodically revisit the processes to make necessary course corrections and enhancements.
Thinking styles, gender, and decision making in Latin American management
Authors: Ilie Camelia , Cardoza Guillermo
Published: February 2018

Purpose

Many studies have analyzed how gender diversity and local culture condition the cognitive styles of managers and affect decision-making processes in organizations. Gender diversity has been defended from an equality perspective; it has been argued to improve decision-making processes and to have a positive impact on companies’ return on investment. The purpose of this paper is to analyze the differences between the thinking styles of men and women, in Latin America and the USA that support decision-making processes. An argument is given in favor of gender diversity in management teams, because of its positive implications in decision making.

Design/methodology/approach

The measurement instrument used was the Neethling Brain Instrument, developed based on recent neuroscience discovery. The sample comprised 1,216 executives from the USA and several countries in Latin America and the Caribbean, who have participated in executive training programs.

Findings

The results show differences in thinking styles by gender, but no differences were found in thinking styles or decision making between men and women at the same managerial level in either of the two regions. Similarly, results suggest that executives in the USA tend to base their management models on strategic thinking styles that focus on interpersonal relations and involve risk taking, while executives in Latin American countries tend to prefer thinking and management styles focusing on data analysis, execution, planning, and process control.

Originality/value

The results of the present study show that, in all regions, men score higher in rational thinking styles associated with the cortical areas, while women gravitate toward thinking styles where emotional schemes prevail, related to subcortical areas. These results could be useful for organizational leaders in charge of allocating roles and tasks to people, based on their thinking style strengths. The results can also be very valuable for Latin American organizations to design specific training and development programs for men and women accordingly with their individual needs and their managerial roles. They can also support the argument that diverse gender teams will guarantee complete decision-making processes.
The association between board gender diversity and financial reporting quality, corporate performance and corporate social responsibility disclosure
Authors: Pucheta-Martínez María Consuelo , Bel-Oms Inmaculada , Olcina-Sempere Gustau
Published: February 2018

Purpose

Companies, politicians, the mass media, legislators, scholars and society in general have shown a growing interest in how board gender diversity affects a firm’s decisions. This concept has been developed because some nations have introduced voluntary policies to regulate and increase the proportion of female directors on corporate boards. Thus, the purpose of this paper is to review previous research based on board gender diversity as a corporate governance mechanism and its effect on some firms’ business decisions: financial reporting quality (FRQ), firm performance and corporate social responsibility (CSR) reporting.

Design/methodology/approach

The authors focus on the agency and stakeholder theory to examine the link between female directors on boards and FRQ, CSR disclosure and firm performance.

Findings

This review provides researchers a structure that can identify the benefits and disadvantages of including female directors on boards regarding three particular corporate outcomes (FRQ, firm performance and CSR reporting).

Originality/value

This study provides a review of past literature on firm performance, CSR disclosure and FRQ from 1975 to 2017, and it contributes to past research by giving a broad overview of the main results of the association between female board directors and corporate decisions. The findings have implications for governments, academics and company managers.
Graduate work-readiness challenges in the Asia-Pacific region and the role of HRM
Authors: Verma Prikshat , Nankervis Alan , Priyono Soegeng , Mohd Salleh Noorziah , Connell Julia , Burgess John
Published: February 2018

Purpose

The purpose of this paper is to focus on graduate work-readiness challenges in three Asia Pacific economies (Malaysia, Indonesia and Australia), and the roles of three main stakeholders (government, employers and industry) in the process. The intention of the paper is to design a stakeholder-oriented HRM model to address the identified graduate work-readiness challenges.

Design/methodology/approach

A qualitative triangulation method comprising interviews and focus groups was used with participant samples for each country – Australia (19), Indonesia (19) and Malaysia (15). Stakeholder-oriented HRM theory underpins the conceptual framework for the paper.

Findings

All three countries are currently experiencing difficulties attracting graduates with the required portfolio of qualifications, skills and personal capabilities. The reported effects include: constraints on national economic growth, future production structures, and long-term socio-economic development. Based on a review of the work-readiness and stakeholder-oriented HRM theory literature, it is posited that graduate work-readiness challenges can be effectively addressed by HR professionals in partnership with other key stakeholders.

Research limitations/implications

The study sought the input of only three stakeholder groups for ascertaining graduate work readiness challenges, there is a strong case to include other groups including students/parents and secondary schools.

Social implications

Bridging the graduate skills gap between government, employers and educational institutions is an important area in which HR professionals can contribute by reducing the mismatch between demand and supply through influencing and balancing the interests and goals of key stakeholders.

Originality/value

This study makes a contribution to the extant literature as it explores the role of HR professionals in relation to a multiple stakeholder strategy to address these challenges in the less-explored Asia Pacific region.
The challenges of state intervention in Singapore’s youth labour market
Authors: Waring Peter , Vas Christopher , Bali Azad Singh
Published: February 2018

Purpose

The purpose of this paper is to assess the efficacy of the policy measures to encourage young Singaporeans to pursue employment in the manufacturing sector while at the same time discouraging the sector’s traditional dependence on low-cost foreign labour. In doing so, the paper sheds light on the challenges faced by small and medium enterprises (SME) as well as the less than optimum impact the policy rhetoric has had on redirecting the aspirations of young people away from tertiary qualifications attainment and towards vocational skills development.

Design/methodology/approach

The paper draws on primary survey data of 222 manufacturing firms and in-depth interviews with 20 SME leaders in Singapore.

Findings

The paper argues that despite the government’s policy efforts to encourage the employment of young Singaporeans in the manufacturing sector, the impact has been negligible. Even with moves to increase the transaction costs of employing foreign workers, the findings indicate that SMEs have not changed their staffing policies. Indeed, the results lay bare the low cost-low skill/low productivity trap that most SMEs now find themselves in. The government’s efforts to discourage the pursuit of tertiary qualifications in favour of vocational qualifications are unlikely to succeed.

Originality/value

The value of this research is fourfold. First, it exposes the difficulty of policy overcoming path dependency. Second, it sheds light on the need for government to rethink its policy approach in how best to re-tool human capital for traditional industry sectors like manufacturing. Third, the results show that there is limited efficacy in simply increasing transaction costs and altering rhetoric to discourage attainment of tertiary qualifications unless vocational employment is adequately remunerated. And finally, the results indicate that firms in the manufacturing sector need to embrace new business models, practices and technologies that are reflective of the digital era to be able to attract youth.
Scale development for the inter-firm market orientation concept
Authors: Francescucci Anthony , Henneberg Stephan C. , Naudé Peter
Published: February 2018

Purpose

The purpose of this paper is to develop and validate a scale for inter-firm market orientation (IMO) based on an original conceptualization by Elg (2008). Building on the MARKOR scale, the IMO scale is introduced to better understand the market orientation efforts that occur within business relationships.

Design/methodology/approach

After establishing a conceptualization of IMO, an initial list of scale items is developed by adapting the original MARKOR scale. Several phases of qualitative pre-tests have been conducted with both academic experts and several manufacturer and reseller partner executives to assess the applicability and clarity of the measurement instrument. Using a quantitative survey design, the measurement instrument has been validated by relationship partner managers from both manufacturer and reseller companies.

Findings

The results of the analysis reveal that IMO is a second-order formative construct consisting of two first-order reflective constructs termed joint intelligence cooperation and joint customer responsiveness.

Practical implications

The operationalization of IMO suggests to manufacturers and their partners that the market intelligence cooperation efforts between them should be more focused on intelligence about the end users and less on general market trends. Further, the customer responsiveness efforts between the partners tend to be more reactive in nature, unlike the proactive stance in intra-firm market orientation.

Originality/value

The paper extends the notion of focal firms’ market orientation to IMO, which exists between partners in business relationships, and does so by developing a conceptualization and measurement instrument for IMO. This newly developed construct and scale can be used in future research to explore in greater depth the interplay between IMO and firm performance.
Finding the way into a global industry
Authors: Sampson Helen , Turgo Nelson Nava
Published: February 2018

Purpose

Gatekeepers in social research are regularly taken for granted in the associated methods literature, yet they constitute an interesting social phenomenon in themselves as powerful and normally unpaid agents of research access. Questions relating to the recruitment of potential gatekeepers and to the nature of the rewards that they might seek are under-considered and locating key gatekeepers is often characterised (perhaps inadvertently) as a matter of luck or happenstance. The paper aims to discuss these issues.

Design/methodology/approach

This paper is a multi-sited ethnography based on maritime industry conferences held annually in Europe and Asia. The two authors attended 18 of these conferences either as regular delegate or as a speaker. In these conferences, they maintained fieldnotes and formally and informally interviewed participants both face to face and e-mail.

Findings

Every year executives come together at commercially organised conferences focussed upon human resource management in the shipping industry. At these events, major global players discuss a programme of issues related to the business of recruiting and training seafarers. However, these international conferences are both much more and much less than they seem. They are crucial in establishing reputational capital and provide researchers with key venues for negotiating research access.

Originality/value

This paper argues that unlike most conferences, these can only be seen as “field configuring events” to a very limited extent but that they nonetheless serve an important purpose in securing symbolic, and more significantly reputational, capital for both individual delegates and interested academics. The paper further argues that resourceful researchers can mobilise such capital in their favour in negotiating research access contributing new ideas to the literature on gatekeepers and on research access.
Fucking law (a new methodological movement)
Authors: Brooks Victoria
Published: February 2018

Purpose

The purpose of this paper is to set the groundwork for a new methodological movement. The author claims that methodological strategies must take as their object the laws with found sexual identity, or rather should be “fucking with” law by creatively confronting, occupying and agitating limiting ethical frameworks that control access to the field. The movement is ethnographic, since it finds research ethics and “straight” academic space to be where these rules are the most harmful in limiting access to the field, for female researchers, in particular.

Design/methodology/approach

The approach (but also to some extent the target) is on Deleuzian and post-Deleuzian’s philosophy, whose theoretical leaps have sought to shift and cause slippage in laws of sexual identity. However, when these laws are tested by researchers proposing to access the field, specifically ethnographically and autoethnographically, it is clear they have not “slipped” at all. This is clear through the questions raised by ethics committees. Fucking law, therefore, becomes a methodological movement intimately connecting ethical agendas and sex as an encounter in the field.

Findings

The author claims that the methodological movement of “fucking” law captures, or at least attempts to capture, the slipperiness of the body, the encounter, the research project and sex itself. The movement, “fucking law”, is essential in agitating and occupying the limiting institutional research agendas and their ethical frameworks.

Practical implications

The implications of “fucking law” will be necessarily unpredictable, but the main practical and connected social implication is questioning as to why more women are not practically questioning arguably one of the biggest questions: the ethics of sexuality. Fucking law argues for the questioning of these laws with bodies, and experimenting with philosophies which underpin and create institutional ethical rules.

Originality/value

This is the first work of its kind by a female autoethnographer challenging the ethics of sexuality, arising from a participatory field project. It also evaluates and confronts the ethics of the field as a whole: from the researcher herself, to her academic environment and sexual life, to the field itself and the writing up of the project.
Welding technology as the moderation variable in the relationships between government policy and quality of human resources and workforce competitiveness
Authors: Fernandes Adji Achmad Rinaldo , Taba Idrus Muhammad
Published: February 2018

Purpose

This paper aims to investigate the moderation effect of welding technology on the relationship between government policy and quality human resources and workforce competitiveness.

Design/methodology/approach

The research is quantitative in nature, i.e. it aims to explain the causality relationship between variables. This research is quantitative research, it aims to explain the causality relationship between variables. The analysis tool was generalized structure component analysis.

Findings

First, government policy has a significant and positive effect on workforce competitiveness, indicating that higher government policy will result in higher workforce competitiveness. Welding technology is the moderating variable in the relationship between government policy and workforce competitiveness. Higher implementation of welding technology will strengthen the relationship between government policy and workforce competitiveness. Second, quality of human resources has a significant and positive effect on workforce competitiveness; higher quality of human resources will therefore result in higher workforce competitiveness. Welding technology is the moderating variable in the relationship between quality of human resources and workforce competitiveness. Higher implementation of welding technology will therefore strengthen the relationship between quality of human resources and workforce competitiveness.

Originality/value

The moderating effect of welding technology in the relationships between government policy and quality of human resources and workforce competitiveness has not been comprehensively studied yet; the present study fills this gap.
Land‐use intensity indirectly affects ecosystem services mainly through plant functional identity in a temperate forest
Authors: Chillo Verónica , Vázquez Diego P. , Amoroso Mariano M. , Bennett Elena M.
Published: February 2018

Land‐use change is known to affect biodiversity, and there is increasing concern regarding how these changes may impact the provision of ecosystem services. Although functional composition (diversity and identity) could influence ecosystem properties and services at the community level, there is little quantitative understanding of these relationships in the field. Here, we evaluate the direct and indirect effects (through ecosystem properties) of biodiversity on the provision of multiple ecosystem services in native mixed forest in north‐west Patagonia, and how land‐use intensity influences these relationships.

We used structural equation modelling to test hypotheses regarding the relationship between understorey plant functional composition, two ecosystem properties, four ecosystem services and silvopastoral use intensity (SUI). We also evaluated two alternative models to assess the mechanism behind biodiversity and ecosystem properties relationships (biomass ratio and niche complementarity). Finally, we performed pairwise correlations to identify synergies and trade‐offs between ecosystem services.

SUI affected functional composition, and the provision of three out of four ecosystem services was indirectly affected by land‐use intensity through changes in ecosystem properties. We found that this indirect effect of biodiversity on ecosystem services happens mainly through changes in functional identity rather than functional diversity. Under increasing land‐use intensity, functional composition changed towards a community characterized by a resource acquisition strategy. Trade‐offs between ecosystem services (provisioning vs. regulating) were enhanced under high SUI, while synergies where enhanced under low SUI (provisioning vs. cultural). Thus, although the strength of these relationships varied between SUI, its nature (trade‐off or synergy) stayed the same.

Our results expand on previous studies by simultaneously considering the effect of land‐use intensification directly on functional composition and on the ecosystem processes underpinning ecosystem services, as well as on the relationship among them. We provide evidence of an indirect effect of land‐use intensification on multiple ecosystem services through biodiversity. Moreover, we found that functional identity is more important than diversity for ecosystem functionality. Land‐use intensification affects biodiversity, and thus, ecosystem properties, but does not change the relationship among ecosystem services.

A plain language summary is available for this article.
Voices of disaffection: disengaged and disruptive youths or agents of change and self‐empowerment?
Authors: Allan David , Duckworth Vicky
Published: February 2018

This article presents findings from research conducted into school disaffection in the north of England. Bourdieu's concept of capital is utilised to explore the perspectives of 14‐ to 16‐year‐old girls undertaking vocational learning as a strategy for re‐engagement. Data emanate from semi‐structured interviews in which social and linguistic capital in school is identified as a privileged feature of a select few. Thus, within the field of education, capital facilitates student empowerment, whereupon the lack of such can lead to marginalisation, disaffection and, subsequently, disengagement. However, voice is presented as a powerful mechanism for challenging the existing inequities of compulsory schooling in England by validating unacknowledged capital, recognising agency, and thus facilitating the self‐empowerment of disaffected young people. Schools are encouraged to rethink their political stance to consider the potentially detrimental impact of a discourse that validates the dominant sociocultural capital and empowers only those students whose individual dispositions align with institutional practices.
Strengths and limitations of the Education, Health and Care plan process from a range of professional and family perspectives
Authors: Sales Niaomi , Vincent Kerry
Published: February 2018

The introduction of a new Special Educational Needs and Disability (SEND) Code of Practice in 2015 marked one of the most significant reforms to the SEND statutory assessment process in England since its introduction over 30 years ago. This article presents the findings of a small‐scale study that aimed to identify the extent to which the reforms have successfully addressed some of the shortcomings of the former Statementing process. Interviews, questionnaires and a focus group were used to gain the perspectives of parents, young people and professionals from education, health and social care services in two local authorities in the English Midlands. The research found that the new Education, Health and Care (EHC) assessment and planning process has been effective in some areas, particularly in achieving greater parental involvement and a more person‐centred approach. However, important issues remain unresolved. The data suggest that greater consistency in interpreting and applying legislation, and in individual professional practices, are still needed to fully achieve the intentions of the new system. Some recommendations for practitioners are proposed.
Enhancing social interaction of pupils with intellectual disabilities with their general education peers: the outcomes of an intervention programme
Authors: Vasileiadis Ilias , Doikou‐Avlidou Maro
Published: February 2018

The goal of the study was to investigate the outcomes of an intervention programme regarding social interaction of four pupils with intellectual disabilities with their typically developing peers. The programme aimed at enhancing social inclusion of pupils with intellectual disabilities and consisted in (1) the implementation of structured activities designed to promote emotion regulation and appropriate expression, self‐confidence and cooperation, and (2) participation of the target pupils in social activities in the neighbourhood, with the active involvement of school staff members. Data were collected by means of observations, teachers’ reflective journals and semi‐structured interviews with the school staff members and the pupils themselves. Findings revealed significant increases in target pupils’ social interactions with their peers inside and outside the school setting, as well as positive changes in general education pupils’ attitudes, both during and upon the completion of the programme. Factors which contributed to the above‐mentioned changes are discussed in relation to the implications of the study.
Strip Clubs, “Secondary Effects” and Residential Property Prices
Authors: Brooks Taggert J. , Humphreys Brad R. , Nowak Adam
Published: February 2018

Municipalities regulate sexually oriented businesses (SOBs) through the “secondary effects” doctrine, which justifies limiting First Amendment speech protections inside SOBs. Negative effects of SOBs on nearby neighborhood quality are a frequently cited secondary effect. Little empirical evidence exists that SOBs generate such negative externalities. If SOBs generate negative externalities, then nearby property prices should decrease when a strip club opens. We estimate regression models of housing prices to determine the effect of new clubs on nearby residential property prices in Seattle, exploiting the termination of a 17‐year moratorium on openings and find no evidence that strip clubs have “secondary effects.”
Comparative Analysis of Inundation Mapping Approaches for the 2016 Flood in the Brazos River, Texas
Authors: Zhang Jiaqi , Huang Yu‐Fen , Munasinghe Dinuke , Fang Zheng , Tsang Yin‐Phan , Cohen Sagy
Published: February 2018

Accurate and timely flood inundation maps serve as crucial information for hydrologists, first‐responders, and decision makers of natural disaster management agencies. In this study, two modeling approaches are applied to estimate the inundation area for a large flooding event that occurred in May 2016 in the Brazos River: (1) Height Above the Nearest Drainage combined with National Hydrograph Dataset Plus (NHDPlus‐HAND) and (2) International River Interface Cooperative — Flow and Sediment Transport with Morphological Evolution of Channels (iRIC‐FaSTMECH). The inundation extents simulated from these two modeling approaches are then compared against the observed inundation extents derived from a Landsat 8 satellite image. The simulated results from NHDPlus‐HAND and iRIC‐FaSTMECH show 56% and 70% of overlaps with the observed flood extents, respectively. A modified version of the NHDPlus‐HAND model, considering networked catchment behaviors, is also tested with an improved fitness of 67%. This study suggests that NHDPlus‐HAND has the potential for real‐time continental inundation forecast due to its low computational cost and ease to couple with the National Water Model. Better performance of NHDPlus‐HAND can be achieved by considering the inter‐catchment flows during extreme riverine flood events. Overall, this study presents a comprehensive examination made of remote sensing compared with HAND‐based inundation mapping in a region of complex topography.
Draft genome sequence of ramie, Boehmeria nivea (L.) Gaudich
Authors: Luan Ming‐Bao , Jian Jian‐Bo , Chen Ping , Chen Jun‐Hui , Chen Jian‐Hua , Gao Qiang , Gao Gang , Zhou Ju‐Hong , Chen Kun‐Mei , Guang Xuan‐Min , Chen Ji‐Kang , Zhang Qian‐Qian , Wang Xiao‐Fei , Fang Long , Sun Zhi‐Min , Bai Ming‐Zhou , Fang Xiao‐Dong , Zhao Shan‐Cen , Xiong He‐Ping , Yu Chun‐Ming , Zhu Ai‐Guo
Published: February 2018

Ramie, Boehmeria nivea (L.) Gaudich, family Urticaceae, is a plant native to eastern Asia, and one of the world's oldest fibre crops. It is also used as animal feed and for the phytoremediation of heavy metal‐contaminated farmlands. Thus, the genome sequence of ramie was determined to explore the molecular basis of its fibre quality, protein content and phytoremediation. For further understanding ramie genome, different paired‐end and mate‐pair libraries were combined to generate 134.31 Gb of raw DNA sequences using the Illumina whole‐genome shotgun sequencing approach. The highly heterozygous B. nivea genome was assembled using the Platanus Genome Assembler, which is an effective tool for the assembly of highly heterozygous genome sequences. The final length of the draft genome of this species was approximately 341.9 Mb (contig N50 = 22.62 kb, scaffold N50 = 1,126.36 kb). Based on ramie genome annotations, 30,237 protein‐coding genes were predicted, and the repetitive element content was 46.3%. The completeness of the final assembly was evaluated by benchmarking universal single‐copy orthologous genes (BUSCO); 90.5% of the 1,440 expected embryophytic genes were identified as complete, and 4.9% were identified as fragmented. Phylogenetic analysis based on single‐copy gene families and one‐to‐one orthologous genes placed ramie with mulberry and cannabis, within the clade of urticalean rosids. Genome information of ramie will be a valuable resource for the conservation of endangered Boehmeria species and for future studies on the biogeography and characteristic evolution of members of Urticaceae.
Patent rights, innovation, and firm exit
Authors: Galasso Alberto , Schankerman Mark
Published: February 2018

We study the causal impact of patent invalidation on subsequent innovation and exit by patent holders. The analysis uses patent litigation data from the US Federal Circuit Court and exploits random allocation of judges to control for endogeneity of the decision. Invalidation causes patent holders to reduce patenting over a five‐year window by 50% on average, but the effect is heterogeneous. The impact is large for small‐ and medium‐sized firms, particularly where they face many large competitors, and for patents central to their research portfolio. We find no significant effect for large firms. Invalidation also increases exit from patenting by small firms.
Dead poets' property—how does copyright influence price?
Authors: Li Xing , MacGarvie Megan , Moser Petra
Published: February 2018

Copyrights create long‐lived intellectual property in goods ranging from science, literature, and music to news, film, and software. The economic effects of copyright, however, are difficult to identify in modern settings. This article exploits an unintended differential increase in copyright length under the UK Copyright Act of 1814—in favor of books by dead authors—to examine the effects of longer copyright terms on price. We find that a doubling in copyright length was associated with a substantial (roughly 50%) increase in the price of books. Additional years of copyright improved publishers' ability to practice intertemporal price discrimination.
Selling information to competitive firms
Authors: Kastl Jakub , Pagnozzi Marco , Piccolo Salvatore
Published: February 2018

Internal agency conflicts distort firms' choices and reduce social welfare. To limit these distortions, principals dealing with privately informed agents often acquire information from specialized intermediaries, such as auditing and certification companies, that are able to ascertain, and credibly disclose, agents' private information. We study how the structures of both the information provision and the final good markets affect information accuracy. A monopolistic information provider may supply imprecise information to perfectly competitive firms, even if the precision of this information can be increased at no cost. This is due to a price effect of information: although more accurate information reduces agency costs and allows firms to increase production, it also results in a lower price in the final good market, which reduces principals' willingness to pay for information.
Growth promotion and root colonisation in pepper plants by phosphate‐solubilising Chryseobacterium sp. strain ISE14 that suppresses Phytophthora blight
Authors: Sang M.K. , Jeong J.‐J. , Kim J. , Kim K.D.
Published: February 2018

Previously, we selected bacterial strain ISE14 through a sequential selection procedure that included radicle, seedling, and in planta assays and field tests. This strain not only suppressed a destructive soilborne disease, Phytophthora blight, caused by Phytophthora capsici but also increased fruit yields of pepper plants in the fields. This study was conducted to identify strain ISE14 by 16S rRNA gene sequence analysis and to characterise biocontrol and plant growth promotion activities of the strain in pepper plants. Strain ISE14, identified as Chryseobacterium sp., significantly reduced disease severity in plants inoculated with Ph. capsici and promoted plant growth (lengths and dry weights of shoots and roots) compared with those in plants treated with Escherichia coli DH5α (negative control) or MgSO4 solution (untreated control). This strain effectively colonised pepper plant roots as assessed by bacterial population analysis and confocal laser scanning microscopy; it enhanced soil microbial activity and biofilm formation, but not the production of indole acetic acid. Strain ISE14 also solubilised organic or inorganic phosphate by production of acid and alkaline phosphatases or reduction in pH, resulting in enhanced pepper plant growth. This strain exhibited similar or greater activity in disease control and plant growth promotion tests compared with positive control strains Paenibacillus polymyxa AC‐1 (biocontrol) and Bacillus vallismortis EXTN‐1 (plant growth). Therefore, Chryseobacterium sp. ISE14 may be a phosphate‐solubilising and plant growth‐promoting rhizobacterium (PGPR) strain that suppresses Phytophthora blight of pepper. To our knowledge, this is the first report of a phosphate‐solubilising PGPR strain of Chryseobacterium sp. that suppresses the pepper disease.
Prophylactic granisetron for post‐spinal anesthesia shivering in cesarean section: A randomized controlled clinical study
Authors: Abdel‐Ghaffar Hala S. , Moeen Seham M.
Published: February 2018

Background

The serotonergic system is known to be involved in control of post‐anesthetic shivering. Our hypothesis was that prophylactic granisetrone (serotonin antagonist) might reduce incidence of post‐spinal anesthesia shivering in cesarean section.

Methods

Parturient scheduled for elective cesarean delivery under spinal anesthesia were allocated to receive 0.9% saline (Group I, n = 71), 1 mg granisetron (Group II, n = 69), or 0.7 mg granisetron (Group III, n = 72) before the spinal block. Assessment parameters included; hemodynamics, tympanic membrane temperature, neonatal Apgar score, shivering score, patient satisfaction scores about shivering prophylaxis and adverse effects.

Results

Clinically significant shivering was recorded in 55/71 patients (77.5%) in group I, 11/69 (15.9%) in group II and 21/72 (29.2%) in group III (P = 0.000). The intensity of shivering was significantly lower in patients who received granisetron 1 mg compared with granisetron 0.7 mg or saline (P = 0.000). Patients who received prophylactic granisetron 1 mg reported lower mean intraoperative arterial pressure and heart rate values and consumed higher doses of iv ephedrine compared with 0.7 mg granisetron or saline placebo (P < 0.05). Pruritus significantly decreased from (22.5%) in control group to (0%) in granisetron groups (P = 0.000). Nausea was reported in 8 vs 10 and four in group I, II and III, respectively (P < 0.03). Sixteen vs eight and six patients vomited in group I, II, and III, respectively (P < 0.03). Higher patient satisfaction scores were recorded in group II (9.83 ± 0.29, P < 0.03) and III (9.14 ± 1.04, P < 0.04), compared with control group (8.23 ± 1.14).

Conclusion

Prophylactic granisetron effectively reduced incidence and severity of perioperative shivering in a dose dependent manner, compared to placebo controls.