bluuebunny/crossref_metadata_2025 huggingface dataset:
For a Future Free of Violence: Moral Competencies As a Means of Emancipation and Self-Empowerment
Authors: Dutka Joanna
Published: October 2018

The paper explores the role of fostering moral-democratic competencies for violence prevention, in particular in the relation to genderbased, intimate partner and domestic violence. Additionally, significant emphasis is placed on the prevention of revictimisation. Violence prevention is framed with regard to the political importance of violence-free homes and intimate relationships for the empowerment of women. The paper refers to the complex situation of women subjected to abuse and the effects of violence on an individual. As a countermeasure, the paper proposes the development of moral-democratic competencies, and recommends the Konstanz Method of Dilemma Discussion® as an example of an efficient method to accomplish this task.
Philosophy for Communites al Liceo “Govone” di Mondovì (Italy)
Authors: Bevilacqua Silvia , Casarin Pierpaolo
Published: October 2018

In this contribution we shall focus on the project of philosophy for communities carried out at the Liceo “Vasco-Beccaria-Govone” (Mondovì , Italy) within the IX edition (2016) of the CeSPeC Summer School on Futures, imagining the world of tomorrow. Philosophy is understood as a practice, an experience, a creation of concepts, an inquiry, as an exercise of argumentation and research. Thanks to this view, a dialogue has opened up with the pupis of this school. In this contribution we present the perspective of a post-philosophy for children and we understand it as an opportunity for philosophy in itself.
Man and Future: a Palaeontological and Chronological Foundation of Cassirer's Definition of Man as Animal Symbolicum
Authors: Laino Luigi
Published: October 2018

In the present paper, the author aims at laying the foundations of a symbolics of technical gesture, according to the thesis that symbolic faculty is another face of the technological one, and that they are both in truth two sides of the same coin. Accordingly, the author suggests to rename the whole dimension as “meta-environmentality”. The analysis is carried out on the basis of a specific comparison between Cassirer’s definition of “animal symbolicum” and its scientific consistence in the light of modern palaeontology. “Animal symbolicum” is here compared with Leroi-Gourhan’s homo technologicus, and Cassirer’s ideas on human identity tested starting from paleoanthropological data. The result of the inquiry lead us to recognize the urgency of integrating Cassirer’s argument with the primacy of the technological capacity, but a deep analysis of the characterizing attributes of the latter compels us to uphold the symbolic attitude of the technological dimension. The author then sketches a basic description ofthe guidelines of a symbolic theory of technology (especially §§ 6-7), and tries to show how the basic elements of such an approach were familiar both to Cassirer and Leroi-Gourhan. As a consequence of the whole theory, the author elaborates a chronological analysis of human identity, whose basic result is the determination of the future as main temporal dimension of human acting.
Life’s Forces That Sustain and Drive Our Existence Towards. Efforts of Steering One’s Life Through Time
Authors: Bellini Bianca
Published: October 2018

We always live in the present and we always pass through the present, even if we constantly reach out towards the future and towards the past. We move towards an effort of shaping the future and towards an effort of comprehending the past. Our experience of time flows into a relentless stream that inexorably points towards. This entails that the way we experience time is inescapably interwoven with a necessity of giving a direction to this movement towards. Such a necessity brings to light two pivotal questions: how to describe such a relentless movement forwards? Which forces can we rely on to drive our existence towards? This research aims at pinpointing such forces and, in so doing, outlining a phenomenological picture of our multilayer experience of time.
Le présent altéré
Authors: Serrano Gemma
Published: October 2018

Our working hypothesis is that the digital culture is remodeling a temporal affect of existence. We attempt to describe how our experience of present time is altered by the increase of digital memory, together with the progressive disappearance of « memory recall » and expectation. This altered presence opens up loopholes which could be called dreams, desire, promise, latency or God. Thus anticipatory algorithm and data translation of present actions of the subject are not a definitive tragedy of our time.
Digital Platforms: A New Grammar for Territories?
Authors: Grumbach Stéphane
Published: October 2018

Digital platforms are reshaping the geometry of the world. Their wide adoption by the population worldwide for an increasing number of activities, confer them a dominant position, which challenges established powers. Their control over the global flow of data and their algorithmic treatment leads to new asymmetries of power. New systems emerge, that unlike the Westphalian States do not correspond to territories on a map, but to complex networks controlling sectors of activities at a global scale. It is a real challenge and a necessity to reinvent a grammar of territories, to be able to grasp the new objects and their dependencies, and address the related issues of social justice and sustainable interaction with our planet.
Relationship between Social Support and Life Satisfaction of College Students: Resilience As a Mediator and Moderator
Authors: Guo Yuan
Published: October 2018

A total of 843 college students in Guangdong University of Foreign Studies were investigated using a social support evaluation scale, a resilience scale, and a life satisfaction evaluation scale. Results were analyzed using IBM® SPSS 21.0® and Amos 17.0. It was shown that there existed a positive correlation respectively among resilience, social support and life satisfaction. Social support predicted resilience positively and resilience partially mediated the association between social support and life satisfaction. Finally, resilience moderated the association between social support and life satisfaction; the higher the resilience level, the more significant the positive predictive effect of social support on life satisfaction. College students' life satisfaction is closely related to social support and resilience; resilience partially plays a mediating and moderating role between social support and life satisfaction.
Imagining Women’s Suffrage
Authors: Stevenson Ana
Published: October 2018

During the late nineteenth century, the print culture associated with women’s suffrage exhibited increasingly transnational connections. Between the 1870s and 1890s, suffragists in the United States, and then Australia and New Zealand, celebrated the early enfranchisement of women in the U.S. West. After the enfranchisement of antipodean women at the turn of the twentieth century, American suffragists in turn gained inspiration from New Zealand and Australia. In the process, suffrage print culture focused on the political and social possibilities associated with the frontier landscapes that defined these regions. However, by envisioning such landscapes as engendering white women’s freedom, suffrage print culture conceptually excluded Indigenous peoples from its visions of enfranchisement. The imaginative connections fostered in transnational suffrage print culture further encouraged actual transpacific connections between the suffragists themselves.
“A Cross-Fire between Minorities”
Authors: Hong Jane
Published: October 2018

This article examines the Japanese American Citizens League’s (JACL) postwar campaign to secure U.S. citizenship eligibility for first-generation Japanese (Issei) as a civil rights effort that brought Japanese Americans into contention with African American and Afro-Caribbean community leaders during the height of the U.S. Cold War in East Asia. At the same time, JACL’s disagreements with Chinese Americans and Japanese American liberals precluded any coherent Japanese or Asian American position on postwar immigration policy. The resulting 1952 McCarran-Walter Act formally ended Asians’ exclusion from U.S. immigration and naturalization, even as a colonial quota in the law severely restricted black immigration from the Caribbean and galvanized black protest. This episode of black-Japanese tension complicates scholarly understandings of the liberalization of U.S. immigration and naturalization laws toward Asian peoples as analogous with or complementary to black civil rights gains in the postwar years. In so doing, it suggests the need to think more critically and historically about the cleavages between immigration and civil rights law, and between immigrant rights and civil rights.
Green Pharmacy – A Narrative Review
Authors: Toma Alexandra , Crişan Ofelia
Published: October 2018

Introduction. Active pharmaceutical ingredients are present in various sections of the environment, because of both the human and veterinary use of medicinal products. Ways of minimizing the risk of environmental contamination should be observed during all pharmaceutical activities (research, manufacturing, prescribing, dispensing and disposal of medicinal products).Methods. For the present study we searched specific literature on this subject, using the main international databases (Thomson Reuters – Web of Science, SCOPUS and Science Direct).Results. This narrative review focuses on the main aspects concerning environmental contamination with medicinal products. Consequently, the present study is structured on four different topics: environmental research on medicinal products, minimizing environmental contamination, waste disposal management and towards a greener community pharmacy. Conclusion. Waste management activities are important for reducing the presence of active pharmaceutical ingredients in the environment. Pharmacists should inform patients on proper pharmaceutical waste disposal and organize collection programs for unused and expired medicines, in order to develop a greener pharmacy for the future.
Пристигаючі та стиглі насадження сосни звичайної на ґрунтах із кристалічними породами
Authors: Kovalevskii S. В. , Krol A. V.
Published: October 2018

Висвітлено особливості росту пристигаючих і стиглих насаджень сосни звичайної Житомирського Полісся в умовах свіжих суборів на ґрунтах із кристалічними породами та без них. Виявлено вплив наявності кристалічних порід у ґрунті на інтенсивність росту та розвитку окремих дерев та насаджень загалом. Проаналізовано приріст дерев за діаметром та висотою залежно від наявності каменів у ґрунті. З'ясовано, що на стадії стиглості насаджень знижується інтенсивність росту дерев за висотою, послаблюється їх приріст за діаметром. На цій стадії немає диференціації дерев. Показано, що в цьому віковому періоді зменшується приріст гілок за довжиною, тому знижується зімкненість крон у насадженнях, що супроводжується не тільки зміною трав'яних рослин у покриві з тіньовитривалих до світлолюбних, але і з'являється самосів деревних рослин. Наведено результати вивчення впливу доглядових рубань різної інтенсивності на формування крони, приріст за діаметром і висотою, а також продуктивність насаджень на ділянках стиглих і пристигаючих насаджень залежно від наявності кристалічних порід у ґрунті.
Вплив природних факторів на динаміку букового (fagus sylvatica L.) пралісу Українських карпат
Authors: Shparyk Yu. S. , Viter R. M. , Shparyk V. Yu.
Published: October 2018

Міжнародні дослідження 15-річної динаміки букового пралісу проведено на 10-гектарному стаціонарному дослідному об'єкті в Угольському масиві Карпатського біосферного заповідника. Проаналізовано вплив вітровалу 2007 р. та потепління клімату на структурні елементи екосистеми пралісу. Виявлено достовірні зміни окремих показників пралісу внаслідок сильного впливу вітру: найбільші коливання характерні для густоти дерев – після втрати 10 % (у 2007 р.) вже в 2010 р. густота збільшилася на 6, а в 2015 р. – на 59 %; істотно зріс і запас мертвої деревини (відповідно на 41 та 6 %); відносне зменшення найбільшим було для кількості підросту (на 19 та 14 %); зменшення запасу деревини було вже меншим (на 7 і 4 %); зменшення суми площ поперечного перетину було неістотним (на 4 і 2 %). Аналіз реакції букового пралісу на сильний вплив вітру підтверджує гіпотезу про максимальну стійкість таких лісових екосистем до стихійних явищ, а ідентифіковані кількісні зміни дали змогу розробити принципову схему сильного впливу вітру на праліс. Дискусійним залишається питання збільшення приросту за діаметром під впливом потепління клімату – у 2010 і в 2015 рр. воно було достовірним для більшості ступенів товщини, але на його динаміку вплинув також і вітровал через зрідження намету.
Первинне інтродукційне оцінювання декоративних видів роду lupinus в умовах Поділля
Authors: Mazur V. A. , Prokopchuk V. M. , Pantsyreva G. V.
Published: October 2018

Наведено результати первинного інтродукційного випробування квітниково-декоративних рослин, що належать до представників роду Lupinus L. в умовах Поділля. Проаналізовано видовий склад роду Lupinus та визначено перспективність їх використання для озеленення різних об'єктів зони Поділля. Для диференціації рослин відповідно до сфери їх можливого використання наведено морфометричні показники найперспективніших представників цього роду. Встановлено, що всі досліджувані види викликають інтерес як потенційно цінні об'єкти для збагачення асортименту вітчизняних декоративних рослин та є перспективними для поліпшення стану парків, скверів, садків зони Поділля. Враховуючи високі декоративні якості цих видів та широкі можливості їх застосування, квітниково-декоративні рослини представників роду Lupinus L мають важливе значення для садівництва та для поповнення асортименту декоративних культур нашої держави. З'ясовано, що природні можливості представників роду Lupinus, пластичність до зміни їх життєвої форми, висока якість за сукупністю ознак, що визначають їх декоративність, характеризує досліджувані рослини як джерело для інтродукції і збагачення асортименту декоративних культур в Україні. Отже, інтродукція представників роду Lupinus для озеленення дасть змогу значно розширити асортимент декоративно цінних рослин та збагатити культивовану флору зони Поділля та України загалом.
Внутрішньовидова диференціація abies alba Mill. за структурою деревини
Authors: Maksymchuk R. T. , Sopushynskyy I. M. , Kopolovets Ya. M. , Zayachuk V. Ya.
Published: October 2018

Вивчено особливості формування річного приросту ялиці білої з прямоволокнистою та хвилясто-завилькуватою структурою деревини. Розглянуто відмінності абсолютних значень ширини ранньої та пізньої деревини на 40 модельних деревах у шести деревостанах. Встановлено, що ширина ранньої деревини ялиці білої змінюється в середньому від 0,5 до 2,0 мм. Різке збільшення ширини ранньої деревини пов'язано з локальними екологічними чинниками. Абсолютні значення ширини пізньої деревини у прямоволокнистій структурі характеризуються меншими значеннями, ніж у екземплярів із хвилясто-завилькуватою структурою. Середні значення ширини річного кільця прямоволокнистої деревини ялиці білої змінюються в межах від 2,36 до 3,53 мм, а в дерев із хвилясто-завилькуватою деревиною – 3,98–5,74 мм. Встановлено істотну різницю в середніх значеннях ширини річного кільця, що властива для мінімальних та максимальних значень. Середня ширина річного кільця у хвилясто-завилькуватій деревині ялиці білої становить 5,74 мм, а ширина річного кільця змінюється від 1,05 до 11,57 мм. Однофакторним дисперсійним аналізом ширини річного кільця деревини ялиці білої в чотирьох деревостанах встановлено статистично значущу різницю між показниками макроструктури у прямоволокнистій та хвилясто-завилькуватій деревині. Рівень значущості між досліджуваними деревами з прямоволокнистою та хвилясто-завилькуватою деревиною становив р<0,05.
Адаптивність та особливості росту сортів тополі в умовах Поділля
Authors: Neyko I. S. , Kolchanova O. V.
Published: October 2018

Досліджено особливості укорінення та росту сортів тополі. Всього вивчено 10 сортів тополі української та зарубіжної селекції, для яких характерна різна інтенсивність росту в умовах Харківщини. Використано живці таких культиварів: 'Версія', 'Волосистоплода', 'Константа', 'Львівська', 'Новоберлінська', 'Ноктюрн', 'Перспективна', 'Російська', 'Слава України', 'Стрілоподібна'. Оцінено вплив умов середовища (типів лісорослинних умов) на здатність до укорінення та ріст сортів тополі. Для оцінювання взаємодії сорт – середовище розраховано індекси: ековаленсія Вріске, показник стабільності Шукля, ранжування генотипів за стійкістю до середовища, показник стабільності Канга. Комплексна оцінка перспективності сорту включала показники укорінення, енергії росту та адаптивності до умов середовища. За результатами досліджень виявлено, що найоптимальнішими для вирощування тополі є умови сирого груду (D4). Найвищою енергією росту на найбільш зволожених ґрунтах відрізнялися сорти 'Львівська', 'Новоберлінська' та 'Версія'. В умовах мінімального зволоження за висотою переважали культивари: 'Волосистоплода', 'Львівська' і 'Константа'. За комплексною оцінкою щодо здатності до укорінення, інтенсивності росту та адаптивності до умов середовища найперспективнішими є сорти 'Львівська' та 'Новоберлінська'. Сорт 'Волосистоплода' доцільно використовувати як один із найстійкіших у посушливих умовах.
Вікові дерева у складі вуличних насаджень міста Лубен
Authors: Tymoshenko L. М. , Fedko R. М.
Published: October 2018

Проаналізовано зелені насадження центральних вулиць Лубен, видовий склад яких налічує 52 таксони. Для покращення загального стану та видової різноманітності вуличних насаджень визначено основні заходи, які включають, зокрема, підбір стійких видів і форм деревних і кущових рослин. Відповідно до результатів проведеного аналізу, частка голонасінних становить 21 %, покритонасінних – 79 %. За походженням, види природної флори становлять 53 %, а інтродуценти – 47 %. Виявлено, що вуличні насадження здебільшого представлені алейними посадками. Встановлено, що дендрофіти вуличних насаджень відрізняються за віком у межах 10 років. Відповідно до результатів здійсненої інвентаризації, до складу насаджень центральних вулиць міста входять вікові дерева видів Quercus robur L. і Fraxinus excelsior L., вік яких становить від 135 до 400 років. Оцінено загальний стан вікових дерев, визначено необхідність проведення низки заходів для збереження вікових дерев у центральній частині міста. Відповідно до ценотичної ролі цих дерев у вуличних насадженнях – це солітери. Виявлено, що для цих дерев характерні високо підняті крони, де обрізування бічних гілок проводили на висоту 5-9 м. Зазначені об'єкти запропоновано внести до реєстру старовинних дерев і визначити стратегію догляду та проведення еколого-просвітницьких заходів. Пропонуємо надати об'єктам статус ботанічної пам'ятки природи.
Формування каркасу регіональної екологічної мережі східного Поділля на підставі перспективних заповідних об'єктів і територій у структурі лісового фонду
Authors: Yelisavenko Yu. А.
Published: October 2018

Наведено дані про стан і кількісний показник природно-заповідного фонду Східного Поділля в адміністративних межах Вінницької області у структурі лісового фонду. Дослідження виконано на базі лісового фонду 11 лісових підприємств, Вінницького обласного управління лісового та мисливського господарства, які зосереджені в регіоні. За результатами аналізу таксаційних описів лісових господарств регіону з'ясовано, що кількісний показник природно-заповідного фонду не є оптимальним. Унаслідок натурних обстежень встановлено, що лісовий фонд області є резервом для створення нових перспективних заповідних об'єктів і територій у структурі проектованої регіональної екологічної мережі Східного Поділля. На основі базових критеріїв, особливо цінних для збереження лісів, відібрано репрезентативні лісові ділянки високої природоохоронної цінності. Загальна площа відібраних ділянок становить 16160,3 га. Запропоновано такі лісові ділянки внести до наявних категорій заповідності для оптимізації категоріальної структури природно-заповідного фонду. Це дасть змогу підвищити рівень заповідності в регіоні до оптимального. Підвищення рівня заповідності сприятиме ефективному збереженню біотичного та ландшафтного різноманіття та ефективному функціонуванню екомережі.
Дослідження та обґрунтування параметрів замкових з'єднань паркетних дощок
Authors: Bilyk S. I. , Ferents O. B. , Kopynets Z. P. , Storozhuk V. M. , Chyzhevskyy M. A.
Published: October 2018

Встановлено параметри відповідності контролю профілю з'єднання та геометрії паркетних дощок після фрезерування. Виконано статистичний аналіз показників параметрів геометрії паркетних дощок та параметрів контролю сучасного профілю поперечного (торцевого) замкового з'єднання 5G-C відповідно до лекал оптичного проектора та розподілу величин параметрів перепаду і щілини від тестових навантажень. Досліджено показники міцності з'єднання профілю при вертикальних навантаженнях залежно від матеріалу вкладки та положення пластикової вставки. Зроблено практичні висновки згідно з дослідженнями контролю профілю з'єднання 5G-C та дошки загалом після фрезерування в технологічному потоці. Встановлено відповідність значень параметрів при контролі профілю з'єднання та геометрії дошки після фрезерування на проекторі, за шаблоном, за тестами складання і навантаження дощок до нормативних показників та якості. Запропонований перелік заходів щодо економії сировини у виробництві сучасних і традиційних паркетних виробів дасть змогу контролювати питання з раціонального та ефективного використання деревинної сировини, запровадити у виробництво науково обґрунтовані прогресивні норми.
Self-Regulation Assessment Based on Compliance and Noncompliance in Children
Authors: Plata-Caviedes Tatiana
Published: October 2018

En este trabajo llevo a cabo una reflexión acerca de la información que los comportamientos de cumplimiento e incumplimiento nos brindan acerca del desarrollo de la autorregulación en los niños. Sostengo que las diferencias que estos comportamientos revelan en cuanto a la autorregulación dependen del nivel de autonomía de los niños, su motivación y la activación emocional que demuestran cuando desobedecen. Sugiero también algunas metodologías para valorar cada uno de estos factores. Específicamente, propongo diferenciar entre los distintos tipos de cumplimiento e incumplimiento, registrar de manera simultánea el comportamiento de los niños y el tipo de control ejercido por los padres y analizar el comportamiento con el que responden los niños a exigencias legítimas e ilegítimas. Estas distinciones son importantes para un abordaje más completo y preciso del estudio de la autorregulación en los niños
Indirect Evaluation of Bone Saturation with Zoledronic Acid After Long-Term Dosing
Authors: Hortobagyi Gabriel N. , Zheng Ming , Mohanlal Ramon
Published: October 2018

Background

Zoledronic acid (ZA), a potent bisphosphonate used for treatment of bone metastasis, has high bone affinity. This post hoc analysis evaluated the effects of long-term treatment and reduction in dosing frequency of ZA on bone saturation.

Materials and Methods

Pharmacokinetic data from three independent studies, OPTIMIZE-2 (patients receiving ≥9 doses of bisphosphonates) and two phase I studies, CZOL4460503 and CZOL4460506 (patients who were bisphosphonate naïve/bisphosphonate free for ≥1 year after previous dosing), were pooled. Serial urine and plasma samples were used as surrogate markers to determine ZA plasma area under the curve (AUC) over 6 hours (AUC0–6h) and dose excreted in urine over 6 hours (urine0–6h). Potential relationships between the number of years for which patients had been treated previously at time of study entry and AUC0–6h or urine0–6h were analyzed graphically.

Results

Creatinine clearances for patients were similar across the three studies and at all time points analyzed. The levels of AUC0–6h ZA in plasma at week 0 in every (q) 4 and q12 weekly arms of OPTIMIZE-2 were 0.366 h × mg/L and 0.397 h × mg/L compared with 0.345 h × mg/L and 0.356 h × mg/L in CZOL4460503 and CZOL4460506, respectively. In OPTIMIZE-2, the AUC0–6h ZA plasma levels were the same (0.428 h × mg/L) at week 36 in both q4 and q12 arms. The levels of ZA urine0–6h at week 36 in OPTIMIZE-2 (q4 and q12 week arms), CZOL4460503, and CZOL4460506 were 36.6%, 30.8%, 26.5%, and 27.3%, respectively.

Conclusion

Long-term ZA treatment may not impact bone saturation, and ZA dosing frequency does not seem to influence drug retention rates.

Implications for Practice

Zoledronic acid (ZA), used along with standard antineoplastic therapy to treat bone metastases associated with solid tumors and multiple myeloma, requires frequent (every 3–4 or every 12 weeks) long-term administration. This may result in bone saturation and subsequently lead to a higher risk of adverse events such as osteonecrosis of the jaw and atypical fractures. This post hoc analysis used surrogate markers to demonstrate that prolonged ZA administration does not cause bone saturation. Furthermore, reduction in ZA dosing frequency does not affect its retention level in bones over time. These findings will help in addressing clinicians' concerns regarding prolonged ZA administration.
Clinical Benefit to an Aurora A Kinase Inhibitor in a Patient with Metastatic Integrase Interactor 1-Deficient Carcinoma
Authors: Karantanos Theodoros , Rooper Lisa , Kang Youme , Lin Cheng Ting , Wenga Pawla , Sagorsky Sarah , Lauring Josh , Kang Hyunseok
Published: October 2018

Integrase interactor 1 (INI-1)-deficient carcinoma is a rare cancer characterized by the loss of the SWItch/Sucrose Non-Fermentable-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 gene (SMARCB1) and tends to follow an aggressive clinical course. There is no currently available standard therapy option, although a few promising treatment strategies, including enhancer of zeste homolog 2 (EZH2) inhibition, are under active investigation. This report describes a 30-year-old woman with INI-1-deficient carcinoma who progressed on combination chemotherapy and an EZH2 inhibitor. Next-generation-sequencing-based targeted cancer-related gene assay confirmed SMARCB1 loss and revealed other mutations in breast cancer 1 gene and checkpoint kinase 2 gene, which may have impacted her clinical course. After discussion at the molecular tumor board, she was offered alisertib, an aurora A kinase inhibitor, on a single-patient expanded-use program and achieved prolonged disease stabilization. Aurora A kinase inhibition may have an important role in the management of patients with INI-1-deficient tumors, warranting further evaluation in clinical studies.

Key Points

Loss of the SWItch/Sucrose Non-Fermentable-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 gene (SMARCB1), which encodes integrase interactor 1 (INI-1), is associated with various mesenchymal malignancies, but a few carcinomas with rhabdoid features have been recently described as a distinct entity. INI-1-deficient carcinoma can be very aggressive, and there is no known treatment option available. There are encouraging preliminary data with an enhancer of zeste homolog 2 inhibitor, tazematostat, in INI-1-deficient malignancies, including INI-1-deficient carcinomas. Loss of INI-1 can activate aurora A kinase (AurkA), and inhibition of AurkA by alisertib could be a viable option and warrants further investigation in this cancer. Clinical genomic profiling can confirm diagnosis of molecularly defined malignancy and provide insights on therapeutic options.
Religion and Economics: Can We Still Rely on Max Weber?
Authors: Zabaev Ivan
Published: October 2018

The article, within the framework of the logic proposed by M. Weber in The Protestant Ethic and the Spirit of Capitalism, attempts to identify the core ethical category of the Russian Orthodox Church that could function in the same way as Beruf (profession/vocation) does for the analysis of Protestantism and its potential impact on the formation of the economy. The attempt to apprehend this category relies on Weber’s works that analyze the economic ethics of world religions. In particular, an effort is made to interpret the Weberian categorization of Russian Orthodoxy as a “specific mysticism”. The texts of F. Nietzsche and M. Scheler are used to decipher Weber’s thesis. The analysis of the texts of Weber, Nietzsche, and Scheler leads to the assumption that “humility” could be the category in question. In his works on the sociology of religion, Weber used “humility” to describe “mysticism” in the same vein as is “vocation” for “asceticism”. At the same time, Weber reinterprets Nietzsche’s doctrine of ressentiment to construct the typology of economic ethics of world religions. For Nietzsche, humility is often synonymous to ressentiment. In the Weberian interpretation, the thesis on ressentiment becomes a “theodicy of suffering”. In the typology of suffering, humility was associated with contemplation, or the withdrawal from the world, that is, with everything specific for mysticism as it was understood by Weber. M. Scheler also took notice of this and criticized the thesis on ressentiment, contrasting it with humility as the basic Christian virtue. An analysis of the texts of F. Nietzsche, M. Weber and M. Scheler on the ressentiment and ethics of Christianity made it possible to propose a typology of ethics that seems to be suitable for constructing hypotheses about the (potential) influence of Orthodoxy on Russian economic life.
Creative Industries — Models of Development
Authors: Khestanov Rouslan
Published: October 2018

With the rise of the concept of “culture”, numerous attempts were made to integrate it into state policy, but failed. “Culture” then required a clear and unambiguous definition. A new effort, known as the “debate about cultural and creative industries”, was undertaken in a new historical context at the beginning of this century. This article tries to clarify the main arguments and positions in these recent debates, and to analyze the attempt of a new operationalization of culture by means of economic discourse in the critical perspective. This attempt was carried out under the new academic slogan of “creative industries”, with which politicians, international and national functionaries, as well as representatives of the academic community pinned their hopes on the invention of a new model of economic growth. One of the principal theses of the article is that this kind of operationalization is not realistic because “creativity”, like “culture”, is not amenable to any mathematization, commodification, or unambiguous interpretation. The policy of “creative industries” is considered through a tendency to a total commercialization of cultural production and its global standardization. The article analyzes different national models of its implementation, as well as the results. One of the most important outcomes of this policy is a growing distrust of the “archaic” forms of cultural knowledge that have been formed in and by national states: the statistical approach as well as its instruments are inappropriate and inadequate as state-of-the-art when the corporate sector almost completely defines rules and standards of a cultural production. This raises the question of whether the state needs a holistic view of culture and the exercising of control functions in this sector of production. In this perspective, the article raises the problem of whether the policy of creative industries is adequate and appropriate for the Russian Federation.
The Representative Culture of Modern Russian Students
Authors: Filonenko Viсtor , Shtompel Liudmila , Shtompel Oleg
Published: October 2018

The article touches upon the issues of several problems. Firstly, we attempt to determine the methodology of a sociological analysis of culture which is adequate for modern realities. Secondly, we will apply this methodological basis to the cultural specifics of modern Russian students in a transitive, transitional society. It is stressed that the formation of a global innovative society results in a permanent crisis with the destruction of the old sociocultural forms and the emergence of new ones, with the result that culture becomes not a “guardian of the foundations”, but an active “fermenting” power of society. In these nonlinear processes, a special importance is acquired by subjective culture. Based on F. Tenbrook’s ideas, an analysis of monostylism and polystylism of a student’s representative culture is carried out. It is noted that these processes of representation are contradictory and hybrid. Highly-valued by student youth, the values of independence, individuality, and freedom of the post-materialistic plan are represented primarily in the sphere of leisure and free-time activities. The presented typology of students’ lifestyles in the field of educational activity (“professionals”, “ritualists”, “public men”, and “conformists”) fixes a predominantly adaptive strategy of behavior based on the adoption of a paternalistic attitude on the part of the administration and the teaching staff of universities. The article is based on the materials of the authors’ interregional sociological research, conducted in the Southern Federal District in 2006, 2011, and 2016.
“The Only Pictures in Memory of the Great War”: The Heroic Spirit, Orientalism, and the Problems of Representational Depictions of the Russo-Turkish War of 1877–1878
Authors: Teslya Andrei
Published: October 2018

The Russo-Turkish War of 1877–1878 spawned a request from both the government and the public for an appropriate pictorial representation to be evaluated in the categories of ‘high art’, a request which revealed the inability of the predominant aesthetics to be satisfied. The paintings on the subjects of the preceding Balkan Crisis of 1875–1876 easily appealed to the existing reserve of descriptive means in primarily appealing to Orientalist motives by using the international Oriental-artistic language. In this case, painters such as K. Makovsky or V. Polenov did not need to resort to some inversions in the “Turkestan Series” by V. Vereshchagin: the developed artistic language allowed the conveying of the desired content without loss. On the contrary, attempts to present pictorial representations of the Russo-Turkish War found that the old military art was no longer perceived as genuine “art”. Thus, in not being regarded as a proper fixation of “memorable events”, the prevailing new aesthetics was unable to convey the pathos and heroics desired by the authorities. At the same time, it was found that a strong aesthetic effect in military plots was achieved through “seriality”, the interpretation of similar plots as isolated and independent. However, this did not produce a significant effect, that is to say, painting as such was not self-sufficient since it required the assistance of the text, the sequence of images, etc. The problem was reduced significantly with the new aesthetics of the 20th century, and in the last decades of the 19th century, in connection with mentioned above difficulties of painting, historical plots acquired new value, providing new opportunities for the representation of heroic themes while simultaneously giving greater aesthetic freedom.
Political Theology and Secularization: On the Inexorability of a Concept
Authors: Fetisov Maxim
Published: October 2018

The collapse of the Soviet bloc and the demise of grand secular emancipatory ideologies led to a growth of interest in the topics concerning religion and secularization. One of the vivid manifestations of this interest is a significant resurgence of research interest in political theology during the last three decades. The paper is intended to deal not so much with political theology in the narrow sense of the term, usually associated with the names of Carl Schmitt, Leo Strauss or Walter Benjamin as to explore some cases in the history of thought revealing the political power of religion. The first case deals with Michel Foucault’s experience of Iranian Revolution. It argues that his exploration of the so-called “political spirituality”, a vague and widely criticized notion, discloses the problematics of political theology not as a historical inheritance or a marginal intellectual activity but as a living constituent reality pointing towards the limits of Western political mind. The second case is devoted to a widely known study of religion within post-secular societies done by a renowned German philosopher Jürgen Habermas. It claims that his idea of “postmetaphysical thinking” boasting to have done away with the “old prejudices” of classical metaphysics and theology does not suffice to ensure the peaceful coexistence of various religious as well as secular worldviews within the Western public sphere. Postmetaphysical treatment of politico-theological problems as irrelevant leads to their reappearance under the new guises: this is what happened to the “problem of evil” that plays a crucial role in the drawing up of the most part of modern political distinctions. “Evil” is dealt with in the third case, as a subject of political theories of radical democracy. Some proponents of radical democracy such as Paolo Virno, Antonio Negri and Michael Hardt consider that part of political theology to be very important for their own projects of “non-sovereign” political institutions that will arise when the current crisis of modern political rationality is over. The paper comes to a conclusion with the idea that political theology should be considered not only as a radical opposite to a political philosophy or secular reason in general but also as an ever-present possibility that comes to reactivation in the moments of crisis.
Global (Im)mobility in the Mirror of Postmodern Transformations: The Political Aspect
Authors: Tormosheva Vera
Published: October 2018

The increasing spatial fluidity of the population in general and the inclusion of a wider range of people in international migration in particular is recognized as one of the most visible manifestations of globalization. However, processes contributing to the movement and global relations at the same time generate physical and socio-political immobility, alienation, and dissociation. The phenomenon of (im)mobility is considered from a political point of view. Making use of the institutional approach, the author defines (im)mobility as a process caused by international and national political institutions’ activities, on one hand, and stimulating the emergence of formal and informal political practices, on the other hand. Government regulation of cross-border migration is reflected in the demands of the valid grounds for the legal entering the territory of a state, the development of distance forms of mobility management, the establishment of financial mechanisms, and the imposition of restrictive migration measures. The isolating practices of modernity meet up with postmodern digital practices. Herewith, political barriers prevent the movement of potentially dangerous individuals and groups, and those not representing a danger to the community, violating human rights and fundamental freedoms, which are so-called mobility rights. Initiatives performed bypolitical parties and public associations prevent mobile citizens from accessing not only political leadership, but also their participation in political agenda setting.
Social Mobility: Success or Failure?
Authors: Vanke Alexandrina
Published: October 2018

Lawler S., Payne G. (eds.). (2018). Social Mobility for the 21st Century: Everyone a Winner? L.: Routledge. 184 P. ISBN 9781315276588
Structural Position of the Priest in Gift-Exchange Systems
Authors: Emelyanov Nikolay , Yudin Greg
Published: October 2018

In this paper, we argue that the priest has a unique structural position to initiate and promote gift exchange. Gift exchange is an important mode of economic integration, one that prevents both cutthroat competition and a parasitic dependence on a centralized hierarchy. In dwelling on gift exchange theory, we demonstrate why the promotion of gifts is largely suppressed nowadays: Marcel Mauss’ second imperative of the gift, that is, the obligation to receive gifts, becomes inoperative under neoliberal capitalism. We rely on Marshall Sahlins’ and Chris Gregory’s analyses to argue that gift giving can be de-blocked by introducing the position of the ‘excluded participant’ who takes part in the gift exchange system but is known to have no self-interest. His presence enables other participants to accept gifts without being afraid of falling into personal bondage. We analyze the Christian theological ideas of the function of the priest in reaching the conclusion that priests are predisposed to take the position of the ‘excluded participant’. On one hand, the priest in persona Christi acts neither on his own behalf nor for his own self-interest, while on the other hand, he remains a member and governor of the community. Historical sources confirm that generating the gift exchange has always been the key activity of priests in Christian communities.
Not All Will Be Saved: The Boundaries of the Political Community as a Socio-ontological Premise
Authors: Kildyushov Oleg
Published: October 2018

The article offers an exposition of the range of topics discussed at the events of the Centre for Fundamental Sociology at the National Research University Higher School of Economics in 2017–2018. These topics were generally connected with the basic theme of the return of the sacred to the world of late modernity which seemed to be completely secularized long ago. Special emphasis is given to the role the state plays in this process of the political rehabilitation of the transcendent. The statement of the problem starts with the analysis of significant structural changes within the global discursive landscape, including the demise of the leading role of triumphalist globalization narratives which, until recently, dominated the sphere of values and symbolic meanings. Then it raises the question of the return of the state as an operator of worldly, secular salvation, which, through its institutions, ensures the inclusion of the social world into the transcendent one, thereby defining the circle of those to be rescued. A short historical-philosophical excursus then demonstrates the rooted-ness of the problem of borders of communities in solidarity united by certain transcendent values in the tradition of social science since the times of antiquity. The next section, appealing to the Aristotelian understanding of the political, proposes a participatory model of the mutual recognition for the members of a certain “We”-group structurally separated from other historically-contingent communities of fate. By conceptual means, the article offers an analysis of the attempts to overcome the inevitably discrete character of social ontology undertaken by universalist discourse through the return to cosmopolitan utopias such as projects of global citizenship, post-national inclusive politics, etc. Finally, the text proposes a reconstruction of the alternative line of argumentation usually associated with the names of Aristotle and Rousseau, but explicitly developed by Carl Schmitt. In this line of reasoning, homogeneity is postulated as a condition of the possibility for any community of solidarity. The article offers preliminary conclusions on the relevance of this topic to the theory of social order.
PERAKENDE İŞLETMELERİN BÜYÜKLÜĞÜNÜ ETKİLEYEN UNSURLAR ve DAĞITIM KANALINDAN BEKLENTİLERİ
Authors: Gedik Hasan , Çimen İsa
Published: October 2018

Lastik
otomotiv endüstrisi için vazgeçilmez bir girdi kalemi olup birçok kullanıcıya
bu sayede ulaşmaktadır. Otomotiv endüstrisi için olan önemi, geniş kitlelere
ulaşan bir sektör olması, elde edilen nicel verilerin yorumlanıp perakende noktalarının
büyüklüğünün katılımcı özelliği ve firma niteliği boyutunda analiz yapılması ve
katılımcıların dağıtım kanallarından olan beklenti düzeylerini ölçüp hem lastik
perakende noktalarına hem de dağıtıcılarına gelecekteki sektör planlarına katkı
sağlayacak olması araştırmayı önemli kılmıştır.

Araştırma
katılımcı özelliklerini, firma niteliklerini belirlemek ve bunları hem
çalışılan firma hem de dağıtıcı büyüklüğünü belirleyen değişken boyutlarında analiz
etmek ve perakende noktalarının dağıtıcılarına verdikleri önemlilik boyutlarına
dair ölçümlemeler yapmayı amaçlamıştır. Belirtilen amaçlar doğrultusunda Konya
bölgesinde faaliyet gösteren 137 firmadan 114’ü ile 01Eylül–20 Ekim 2016
tarihleri arasında yüz yüze görüşülerek, anket çalışması ile veriler toplanmış
ve uygulamalı nicel bir araştırma yapılmıştır. Konya bölgesinde ve bu bölgedeki
lastik perakende noktaları üzerinde yapılmış olmasını araştırmanın
sınırlılıkları oluşturmuştur.

Katılımcı
demografik özelliklerinden eğitim durumu, çalıştıkları firmanın büyüklüğünü
belirleyen çalışan sayısına göre anlamlı farklık göstermiş olduğu, merkezi
eğilim istatistik analizine göre dağıtım kanalı boyutunda finans, teknik ve
ürün en fazla önemsenen olurken, reklam, sipariş ve sevkiyat en az önemsenen
boyutları oluşturduğu sonucuna ulaşılmıştır. Lastik perakende firma
işletmecilerine bir takım eğitim programlarına dahil olmalı ve dağıtıcıları
finans teknik ve ürün boyutunda onları desteklemelerinin gerekli olduğu
görülmüştür.
HAFIZ İMAM HATİP ORTAOKULLARINDAKİ HAFIZLIK EĞİTİMİNE İLİŞKİN ÖĞRETİCİ VE ÖĞRENCİ GÖRÜŞLERİ
Authors: Adıgüzel Abdullah , Kılıç Abdurrahman , Aslanargun Engin , Şahin Şeyma , Ökmen Burcu , Boyacı Zeynep
Published: October 2018

Bu
çalışmanın amacı; proje hafız imam hatip ortaokullarındaki hafızlık eğitimi
hakkında, hafızlık öğreticileri ve öğrencilerinin görüşlerini belirlemektir.
Araştırmada nitel araştırma desenlerinden durum çalışması deseni
benimsenmiştir. Araştırmanın çalışma grubunu, Marmara Bölgesi’nde hafızlık
eğitimi veren bir imam hatip ortaokulunda görev yapan 20 hafızlık öğreticisi
ile aynı okulda hafızlık eğimi alan 48 öğrenci oluşturmaktadır. Hafızlık
öğreticilerinin seçiminde ölçüt örnekleme yöntemi, öğrencilerin seçiminde ise
aykırı örnekleme yöntemi kullanılmıştır. Araştırma verileri odak grup görüşmesi
yöntemi ile toplanmıştır. Hafızlık eğitimi veren öğreticilerle üç, hafızlık
eğitimi alan öğrencilerle sekiz ayrı odak grup görüşmesi gerçekleştirilmiştir.
Verilerin analizinde içerik analizi yöntemi kullanılmıştır. Elde edilen
veriler, ayrı ayrı kodlanmış ve elde edilen kodlar ana temalar ve alt temalar
altında birleştirilerek tablolaştırılmıştır. Hafızlık öğreticilerinin ve
öğrencilerinin hafızlık eğitimi hakkındaki görüşleri araştırma problemlerine
uygun olacak şekilde “Hafızlık Eğitimini Olumlu Etkileyen” ve “Hafızlık
Eğitimini Zorlaştıran” faktörler olmak üzere iki ayrı başlık altında
sunulmuştur. Elde edilen sonuçlara göre çeşitli öneriler geliştirilmiştir.
SORU VARSA, ÖĞRENME DE VARDIR
Authors: Kubat Ulaş
Published: October 2018

Bu araştırmanın
amacı fen bilgisi öğretmenlerinin öğrenme öğretme sürecinde soru cevap
tekniğini nasıl kullandıkları çok yönlü ve derinlemesine incelemektir. Bu amaç
doğrultusunda veri toplama aracı olarak, fen bilgisi öğretmenlerinin soru cevap
tekniğini nasıl kullandıklarına yönelik araştırmacı tarafından geliştirilen
yarı yapılandırılmıştır görüşme formu geliştirilmiştir. Soru cevap tekniği
öğretmenler tarafından çok sık kullanılan bir tekniktir. Araştırmada nitel
araştırma yöntemi kullanılmıştır. Araştırmanın çalışma gurubu; 2017- 2018
eğitim öğretim yılında Muğla ilinde görev yapmakta olan on iki fen bilgisi
öğretmeninden oluşmaktadır. Araştırma bulgularına göre fen bilgisi öğretmenleri
soru cevap tekniğini öğrencilerin ön bilgilerini yoklamak, ilgisini ve
dikkatini çekmek için kullanmaktadır. Ayrıca öğretmenler soruların kolay ve
merak uyandırıcı nitelikte olması gerektiğini belirtmişlerdir.