bluuebunny/crossref_metadata_2025 huggingface dataset:
Effects of opioid receptor stimulation and blockade on touch pleasantness: a double-blind randomised trial
Authors: Løseth Guro Engvig , Eikemo Marie , Leknes Siri
Published: December 2018

The μ-opioid receptor (MOR) system has long been thought to underpin the rewarding properties of pleasant touch. Numerous non-human animal studies implicate MORs in social behaviours involving touch, but little is currently known about MOR involvement in human touch reward. Here, we employed a bi-directional pharmacological double-blind crossover design to assess the role of the human MOR system for touch pleasantness and motivation. Forty-nine male volunteers received 10 mg per-oral morphine, 50 mg per-oral naltrexone and placebo before being brushed on their forearm at three different velocities (0.3, 3 and 30 cm/s). In a touch liking task, pleasantness ratings were recorded after each 15 s brushing trial. In a touch wanting task, participants actively manipulated trial duration through key presses. As expected, 3 cm/s was the preferred velocity, producing significantly higher pleasantness ratings and wanting scores than the other stimuli. Contrary to our hypothesis, MOR drug manipulations did not significantly affect either touch pleasantness or wanting. The null effects were supported by post hoc Bayesian analyses indicating that the models with no drug effect were more than 25 times more likely than the alternative models given the data. We conclude that μ-opioid signalling is unlikely to underpin non-affiliative touch reward in humans.
Visualizing Individual Outcomes of Social Mobility Using Heatmaps
Authors: Präg Patrick
Published: December 2018

Research on the consequences of social mobility usually draws on information about categorical origin and destination variables as well as an outcome variable. The author shows an example of a heatmap created in Stata to visualize the relationship between social mobility and poor self-rated health in Germany and discusses the advantages of this heatmap approach to other visualization approaches.
Detecting Footnotes in 32 million pages of ECCO
Authors: Abuelwafa Sherif , Zhalepour Sara , Arabnejad Ehsan , Mhiri Mohamed , Greenfield Emilienne , Ascher James P. , Bach Sofia , Svaikovsky Victoria , Moody Alayne , Piper Andrew , Wellmon Chad , Cheriet Mohamed
Published: December 2018

In "An Answer to the Question: What is Enlightenment?", the eighteenth-century German philosopher Immanuel Kant responded to a big question buried in a little footnote. But you wouldn't know it, because contemporary editions of Kant's famous essay no longer reproduce the parenthetical directive that Kant's original essay printed right under the essay's title in the December issue of the Berlinische Monatsschrift in 1784: "S. Decemb. 1783. S. 516." (See December 1783, p. 516). And, in fact, page 516 in the December volume of the Berlinische Monatsschrift 1783 has a footnote: "What is Enlightenment? This question is nearly as important as: what is truth? And should certainly be answered before one starts to enlighten! But I have yet to find it answered anywhere."
Fatigue reduces the complexity of knee extensor torque during fatiguing sustained isometric contractions
Authors: Pethick Jamie , Burnley Mark , Winter Samantha Lee
Published: December 2018

The temporal structure, or complexity, of muscle torque output reflects the adaptability of motor control to changes in task demands. This complexity is reduced by neuromuscular fatigue during intermittent isometric contractions. We tested the hypothesis that sustained fatiguing isometric contractions would result in a similar loss of complexity. To that end, nine healthy participants performed, on separate days, sustained isometric contractions of the knee extensors at 20% MVC to task failure and at 100% MVC for 60 seconds. Torque and surface EMG signals were sampled continuously. Complexity and fractal scaling were quantified by calculating approximate entropy (ApEn) and the detrended fluctuation analysis (DFA) α scaling exponent. Global, central and peripheral fatigue were quantified using maximal voluntary contractions (MVCs) with femoral nerve stimulation. Fatigue reduced the complexity of both submaximal (ApEn from 1.02 ± 0.06 to 0.41 ± 0.04, P < 0.05) and maximal contractions (ApEn from 0.34 ± 0.05 to 0.26 ± 0.04, P < 0.05; DFA α from 1.41 ± 0.04 to 1.52 ± 0.03, P < 0.05). The losses of complexity were accompanied by significant global, central and peripheral fatigue (all P < 0.05). These results demonstrate that a fatigue-induced loss of torque complexity is evident not only during fatiguing intermittent isometric contractions, but also during sustained fatiguing contractions.
Mandatory infectious diseases consultation leads to improved process measure adherence in the management of Staphylococcus aureus bacteremia: A multicentre, quasi-control study
Authors: Valbuena Venus , Bai Anthony D , Showier Adrienne , Meem Mahbuba , Steinberg Marilyn , Bell Chaim M , Morris Andrew M
Published: December 2018

Background: Staphylococcus aureus bacteremia (SAB) results in high morbidity and mortality. Infectious diseases (ID) consultation for SAB has been associated with improved process measures and outcomes in SAB. Recent guidelines have been implemented to include ID consultation in the management of positive SAB culture. We sought to determine whether a policy of mandatory ID consultation for SAB would improve management and mortality. Methods: We conducted a retrospective quasi-experimental study of patients with SAB at three academic hospitals comparing adherence to process measures, and mortality as a secondary measure, before and after implementation of a hospital policy of mandatory ID consultation for all cases of SAB. Results: ID consultation was performed in 239/411 (58%) patients in the pre-intervention period and 196/205 (96%) patients in the post-intervention period (p < 0.0001). Compared with pre-intervention, mandatory consultation was associated with better adherence to quality process measures including echocardiography (319/411 (78%) versus 186/205 (91%) p < 0.0001), subsequent blood culture within 2–4 days (174/411 (42%) versus 143/205 (70%) p < 0.0001) and avoidance of vancomycin as definitive antibiotic therapy for methicillin-susceptible S. aureus (MSSA) (54/347 (16%) versus 13/177 (7%) p = 0.0082). In-hospital mortality rate was 94/411 (23%) in the pre-intervention group and 33/205 (16%) in the post-intervention group. The unadjusted sub-distribution hazard ratio (sHR) for in-hospital mortality in the postintervention period was 0.67 (95% CI 0.45 to 0.99, p = 0.0447). After adjusting for significant prognostic factors, post-intervention in-hospital mortality had an sHR of 0.79 (95% CI 0.52 to 1.20, p = 0.2686). Conclusions: A policy of mandatory ID consultation for patients with SAB was easily implemented leading to consultation in nearly all SAB patients and improved adherence to standard of care process measures. In-hospital mortality did not improve significantly after adjusting for patient characteristics. Our study provides the framework to support this easily implemented institutional policy in academic hospitals.
Tuberculosis of the foot mimicking Charcot arthropathy
Authors: Agabawi Salem , Walkty Andrew , Pilkey Brad , Bhullar Rick , Trepman Elly , Embil John M
Published: December 2018

Mycobacterium tuberculosis bone and joint infection accounts for 2% to 3% of all tuberculosis cases but is uncommon in the foot. A 32-year-old woman had foot pain and swelling, and radiographs showed midfoot bony destruction and fragmentation. She was diagnosed with Charcot arthropathy, but had no neuropathy or improvement despite total contact casting. Bone biopsy 16 months after initial presentation did not show acid-fast bacilli on smear, but M. tuberculosis was recovered on culture; concurrent chest radiographs showed patchy and nodular opacities in both upper lung zones, consistent with previous pulmonary tuberculosis. Sputum smear showed acid-fast bacilli and culture yielded M. tuberculosis. In retrospect, the patient was at increased risk for M. tuberculosis infection because of previous residence in Myanmar and India. Clinicians should consider M. tuberculosis infection in the differential diagnosis of Charcot arthropathy for patients who have exposure history and absence of risk factors for Charcot arthropathy.
Canadian guidelines on HIV pre-exposure prophylaxis (PrEP) and non-occupational post-exposure prophylaxis (nPEP): Discussion beyond the guidelines and commentary on the role of infectious diseases specialists
Authors: Singh Ameeta E , Tan Darrell , Hull Mark , Bogoch Isaac I , MacPherson Paul , Tremblay Cecile , Shafran Stephen
Published: December 2018

Pre-exposure prophylaxis (PrEP) and non-occupational post-exposure prophylaxis (nPEP) are part of combination HIV prevention strategies that include behavioural interventions such as condoms and risk-reduction counselling. A 25-member panel was convened to develop Canadian guidelines for PrEP and nPEP, with the full guidelines recently published in the Canadian Medical Association Journal (CMAJ). This article provides a discussion beyond the guideline, highlighting areas of particular interest to infectious disease (ID) specialists and discusses the possible role of ID specialists as access to both PrEP and nPEP become more widely available across the country.
An Atlantic Canada case of disseminated Streptococcus equi subspecies zooepidemicus infection
Authors: Chang Albert , Webster Duncan
Published: December 2018

Streptococcus equi subspecies zooepidemicus infections in humans can be contracted through contact with domestic animals or unpasteurized dairy products. Although infection in humans is rare, the course can be fulminant. We describe the case of a 75-year-old immunocompetent male who developed disseminated disease with bacteremia, native aortic valve endocarditis, suppurative pericarditis with cardiac tamponade, meningitis, and bilateral endophthalmitis. Despite treatment with pericardial drain placement, intravenous ceftriaxone, and rifampin, the patient unfortunately did not survive. To date, reported cases of disseminated infection by S. equi subsp zooepidemicus are few. Furthermore, with review of the literature, this case demonstrates the broadest organ system involvement reported. Of interest, previous studies have suggested an affinity of this organism for certain organ systems and this case corroborates an emerging association of S. equi subsp zooepidemicus with endophthalmitis. In addition, this is the second Canadian case of documented human infection, with both cases being similar in clinical features, presentation, and geographical location. This case report should serve to warn clinicians about complications and sites of haematogenous seeding in the setting of disseminated S. equi subsp zooepidemicus infections.
Not so pretty in pink: A clinical vignette on invasive fungal sinusitis
Authors: McGuinty Michaeline , Buchan C Arianne
Published: December 2018

Invasive fungal infection is one of the most feared infectious complications in immunocompromised hosts following aggressive chemotherapy for hematologic malignancy and hematopoietic stem cell transplant (HSCT). The more common causes of sinusitis due to fungal pathogens (Mucorales, Fusarium, and Aspergillus spp) make up the majority of cases, but less common pathogens, including a number of dematiaceous fungi, can also be implicated. Early diagnosis is crucial; the mortality associated with fungal sinusitis is high and prompt, aggressive treatment is important for successful management. Prompt accurate microbiologic diagnosis is also crucial to direct effective treatment, especially in cases that do not respond to empiric therapy. Here we present an unusual case of invasive fungal sinusitis in a patient with relapsed refractory leukemia.
Residential Buildings of Neues Bauen in Zagreb between 1928 and 1934
Authors: Kahle Darko
Published: December 2018

Ovaj je članak prerada autorove disertacije „Stambene kuće Novog građenja u sjevernim dijelovima Zagreba u razdoblju od 1928. do 1945. godine”, obranjene 12. travnja 2007. godine na Arhitektonskom fakultetu u Zagrebu, pod mentorstvom professora emeritusa Nikole Filipovića. A 39 ugrađenih najam nih stambenih zgrada i 109 vila Novoga građenja, podignutih između 1928. i 1935. godine, pokazuju snažan doprinos zagrebačkih arhitekata modernome pokretu.
Building Revitalization and Integration of Solar Systems in Sustainable Rural Tourism
Authors: Aleksić Ljiljana , Kosorić Vesna
Published: December 2018

Ovaj se rad bavi problematikom održivoga razvoja u ruralnome turizmu s osobitim osvrtom na obnovu zgrada i ugradnju solarnih sustava. U njemu se definiraju relevantni principi i kriteriji, razmatraju estetski, energetski, ekonomski, društveni i ekološki aspekti te analiziraju mogućnosti i rezultati. Rad prezentira i neke europske primjere održive obnove zgrada u održivom razvoju ruralnog turizma.
Amfiteatar u Puli
Authors: Krizmanić Attilio
Published: December 2018

U članku se sažeto obrađuju nove spoznaje i rezultati istraživanja s najnužnijim informacijama o izvornom izgledu Amfiteatra u Puli podignutog sredinom 1. st.pr.Kr., od kojeg su se do danas, usprkos znatnim višestoljetnim destrukcijama, ipak sačuvali opsežni ostaci koji omogućuju vjerodostojnu virtualnu rekonstrukciju njegovih nestalih dijelova. Istaknuta je i njegova posebnost kao rano arhitektonsko djelo ostvareno na prijelazu amfiteatara iz drvene u kamenu konstrukciju, potvrđenu četirima istaknutim specifičnim tornjevima s ukrižanim drvenim stubištima, drvenim palubama i velarijem, kao i drugim prostornim značajkama. Proučavanjem integralnog izgleda Amfiteatra (1976.2016.) došlo se do novih saznanja u otkrivanju bitnih arhitektonskih sklopova i detalja njegova izvornog stanja.
Architect Zlatko Neumann
Authors: Kahle Darko
Published: December 2018

Članak prikazuje engleskom govornom području dosad nepoznato djelovanje arhitekta Zlatka Neumanna od 1945. gotovo sve do njegove smrti 1969. godine. Kao jedan od projektanata palače Saveznoga izvršnog vijeća [SIV] u Beogradu 1947., dao je enorman doprinos suspregnutoj ljepoti tlocrtnog oblika blago svinutoga H-profila današnje „Palate Srbije”. Godine 1954. započeo je praktično neovisnu arhitektonsku praksu kao direktor Arhitektonskoga projektnog biroa „Neuman” (sic!) sve do umirovljenja 1963. godine.
Peningkatan Hasil Belajar Matematika melalui Metode Kelompok Tutor Sebaya
Authors: Nugroho Dimas Adi
Published: December 2018

This research was conducted based on the issue of the learning process less effective. The purpose of this research is to improve the results of mathematical learning through peer tutor groups method. This research was conducted on grade V SD Negeri 2 Shaman Krinjing Magelang Regency. The design of this study using a research action class that consists of two cycles. Each cycle there are four stages, namely planning, implementation, observation, and reflection. This research consists of variable input in the form of the results of learning math is low, the process variables in the form of peer tutor groups, methods and variables are output in the form of higher mathematics learning outcomes. Data collection method using tests and observation. The conclusions of this study, namely the application of the method of peer tutor groups can enhance the results of learning math grade V SD Negeri 2 Shaman Krinjing Magelang school year 2016/2017. The results of this study showed that there was increased after the action. This is proven by the results of the study before action amounted to 23% increase in cycle 1 of 38% and in cycle 2 to 76%. The results ofsuch research has showed that the indicator of success has been achieved, namely75%, so this research is declared successful.
Quel modèle de management pour les organisations temporaires ?
Authors: Mazzorana-Kremer Florie
Published: December 2018

Les organisations temporaires sont de plus en plus fréquentes et leurs caractéristiques atypiques mobilisent de nouvelles pratiques managériales. L’étude d’un projet de renouvellement de stockage de gaz montre qu’une marge de flexibilité dans la définition et la coordination des tâches en facilite le pilotage. Cette flexibilité s’appuie sur des réunions et retours d’information fréquents ainsi que sur une excellente communication. Ces mesures sont d’autant plus efficaces que des rôles clefs, qui orchestrent les relations entre acteurs, sont formellement mis en place.
Les pratiques des firmes en matière de rémunération à long terme des dirigeants
Authors: Bancel Franck , Philippe Henri
Published: December 2018

Cet article s’intéresse à la composante à long terme de la rémunération des dirigeants et plus précisément, aux critères financiers, comptables et non financiers qui permettent d’établir que les dirigeants ont atteint leurs objectifs. Après avoir présenté la littérature sur la rémunération à long terme des dirigeants, l’étude montre que les entreprises européennes utilisent différents critères et ne retiennent pas le seul cours de Bourse. Les auteurs présentent en conclusion pourquoi les critères à appliquer doivent être contingents à la situation et au niveau de performance de la firme, à la structure de son actionnariat et aux caractéristiques de ses dirigeants.
BOŞANMIŞ BİREYLERİN BAŞ ETME STRATEJİLERİNİN VE YAŞAM KALİTELERİNİN BAZI DEĞİŞKENLER AÇISINDAN İNCELENMESİ
Authors: SEZER Fahri , GÜRGAN Uğur
Published: December 2018

Bu çalışmada, boşanmanın ayrılan çiftler

üzerindeki çok boyutlu etkisinin ortaya çıkarılması amaçlanmıştır. Bu amaçla,

bireylerin boşanma süreci ile baş etmede kullandıkları stratejilerin ve boşanma

sonrasında yaşadıkları psikolojik sorunların neler olduğu incelenmiştir. Çalışmaya 149 ayrılmış

(boşanmış) birey katılmıştır. Bunların

132’si (% 88.6) kadın, 17’si (% 11.4) erkektir. Çalışmada veri toplama aracı

olarak insanların strese karşı gösterdikleri farklı davranışları ölçen

Başa Çıkma Stratejileri (COPE) ölçeği ile bireylerin yaşam kalitesini ölçmeye

yarayan Dünya Sağlık Örgütü Yaşam Kalitesi Ölçeği Kısa Formu (WHOQOL-BREF-TR)

kullanılmıştır. Verilerin analizi sonucunda boşanmanın bireylerin yaşam

kalitesini etkilediği, cinsiyete göre yaşam kalitesi düzeylerinin farklılaştığı

ve eğitim seviyesinin boşanma ile baş etmede belirleyici bir değişken olduğu

saptanmıştır.
ÖĞRENCİLERİN KARİYER TERCİHLERİNE GÖRE KİŞİLİK ÖZELLİKLERİNİN KARİYER DEĞERLERİ ÜZERİNDEKİ ETKİSİ: İŞLETME LİSANS BÖLÜMÜ ÖĞRENCİLERİ ÜZERİNE BİR ARAŞTIRMA
Authors: YAVUZ Nihan , SAĞLAM Mehmet , ÜLGEN Beliz
Published: December 2018

Bu çalışmada, İşletme lisans bölümü öğrencilerinin

iş hayatında çalışmayı tercih ettikleri departmanlara göre, beş büyük faktör kuramı

kişilik özelliklerinin kariyer değerleri üzerindeki etkisinin incelenmesi ve

aynı zamanda bu tercihlerine göre hem kariyer değerleri boyutlarının hem de

kişilik özellikleri boyutlarının ortalama düzeylerinin belirlenmesi amaçlanmıştır.

İstanbul’da bir devlet üniversitesinde kolayda örnekleme ile belirlenen 414

katılımcı öğrenciye, yüz yüze uygulanan anket aracılığıyla toplanan verilerin

analizinde, SPSS 22 paket programı kullanılmıştır. Araştırmada;

frekans analizi, Kolmogorov-Smirnov testi, faktör analizi, güvenilirlik testi

ve kariyer değerleri üzerinde kariyer tercihlerine göre kişilik özelliklerinin

etkisinin belirlenmesi için regresyon analizi uygulanmıştır. Araştırma

bulgularına göre; muhasebe

kariyer tercihi gösteren öğrencilerin güvenlik kariyer değeri ile uyumluluk

kişilik özelliği; finans kariyer tercihi gösteren

öğrencilerin teknik kariyer değeri; insan kaynakları kariyer tercihi gösteren

öğrencilerin yönetimsel kariyer değeri ve uyumluluk kişilik özelliği; pazarlama

kariyer tercihi gösteren öğrencilerin yaşam tarzı kariyer değeri ve deneyime

açık kişilik özelliği göstermekte oldukları sonucuna ulaşılmıştır.
TÜRKİYE’DE VERGİ-TÜKETİM İLİŞKİSİ: ALKOL VE TÜTÜN ÜRÜNLERİNE YÖNELİK BİR SAHA ARAŞTIRMASI
Authors: ÇETİN Murat , ÖZKAN Ersan
Published: December 2018

Günümüzde ülkeler sosyal ve

ekonomik etkileri nedeniyle alkol ve tütün ürünleri üzerinde

önemli mali politikalar uygulamaktadırlar. Temel bir maliye politikası aracı

olarak vergiler, toplum sağlığını tehdit eden bu tür ürünlerin tüketimini azaltmaya

yönelik kullanılmaktadır. Ancak, burada önemli olan uygulanan vergi

politikalarının etkin olup olmadığıdır. Bu çalışmanın temel amacı, Türkiye’de

alkollü içecekler ve tütün ürünlerinde uygulanan vergi politikalarının

etkinliğini değerlendirmektir. Bu çerçevede, alkollü içecekler ve tütün

ürünlerinin tüketimine yönelik bir saha araştırması gerçekleştirilmiştir. Araştırmada

t-testi,  ANOVA ve korelasyon analizi uygulanmıştır.

Sonuçlar, eğitim ve sağlığın tüketim üzerinde belirleyici rol oynadığını ortaya

koymakta ve Türkiye ekonomisi ile ilgili bazı önemli politika önerilerini de sunabilmektedir.
TÜRKİYE’DEKİ OTEL İŞLETMELERİNİN WEB SİTELERİNİN DEĞERLENDİRİLMESİNE YÖNELİK NİTEL BİR ARAŞTIRMA
Authors: ÜNAL Aydın , ÇELEN Onur
Published: December 2018

Modern

bilgi çağında, internet artık insanların temel ihtiyaçları arasında

gösterilebilmektedir. İnsanlar tüketim tercihlerini ve kararlarını internet

üzerinden verebilmekteler ve internet ortamında yer alan işletmeleri tercih

etmektedirler. Turizm sektöründeki işletmeler de bu değişim sürecinin bilincine

vararak, internet üzerinden tüketicilerine ulaşmaya çalışmaktadırlar. Bu

araştırmanın konusunu turizm işletmelerinin temel yapı taşlarından birisi olan

konaklama işletmelerinin internet kullanımı oluşturmaktadır. Bu bağlamda Türkiye’deki

konaklama işletmelerinin web sitelerinin boyutlarının ve bileşenlerinin

incelenmesi amaçlanmıştır. Araştırma

sonucunda elde edilen veriler bilgisayara kaydedilerek bir veri seti

oluşturulmuştur. İlgili veri seti sosyal bilimler çalışmalarında yaygın bir

biçimde kullanılan Statistical Package for the Social Science (SPSS 17.0)

istatistikî veri programında analize tabi tutulmuştur. Araştırmada turizm

işletme belgesine sahip beş yıldızlı otel işletmelerinin web sitelerine ilişkin

elde edilen veriler yüzde ve frekans değerleriyle analiz edilmiştir. Gerçekleştirilen

analizler neticesinde turizm

işletme belgeli konaklama işletmelerinin büyük çoğunluğunun Akdeniz (%51,8),

Marmara (%17,7) ve Ege (%19) bölgesinde faaliyet gösterdiği ve araştırmaya

dâhil edilen konaklama işletmelerinin genelinin (%95,2) kendisine ait bir web

sitesine sahip olduğu belirlenmiştir. Bulgulara göre, Türkiye’deki konaklama

işletmelerinin web sitelerinde ağırlıklı olarak işletmelerin iletişim ve konum

bilgilerine yer verilmesine rağmen, tüketici dileklerine, isteklerine ve önerilerine

yönelik misafir ilişkileri ve benzeri değişkenlere yeterince yer verilmediği

tespit edilmiştir.
Remote detection of ragweed (ambrosia artemisiifolia l.)
Authors: Plaščak Ivan , Barač Željko
Published: December 2018

The paper presents the contemporary findings of remote sensing regarding the control of common ragweed on agricultural land. The two-year research was performed in co-operation with the company Ciklonzacija Ltd., Serbia. The remote sensing process starts with the collection of images captured by several types of cameras equipped with special filters. Images are obtained by modified cameras mounted on helicopters, drones, and airplanes. Next, a special software is used to produce maps based on the obtained images that show the level of weed spread on agricultural land, illegal waste dumping areas, and other uncultivated areas, i.e. the areas that are potential sources of ragweed spread. The maps have a considerable economic benefit when mapping agricultural, wood, and other areas. Moreover, they reduce the use of human resources, and increase the capacity of data acquisition as well as the accuracy of the model of weed spread and its control.
KONDISI TERMAL PADA PENGHAWAAN ALAMI DI RUANG TUNGGU UTAMA STASIUN SEMARANG TAWANG
Authors: Rusyda Hana Faza Surya , Setyowati Erni , Hardiman Gagoek
Published: December 2018

Abstract:. Thermal comfort is a state of mind that expresses a user's satisfaction with thermal conditions. This study focuses on the design of natural ventilation which is one of the efforts to reduce the heat that exists in the building, especially in maintaining the thermal conditions. Tawang Train Station, Semarang has a natural ventilation design that is still maintained especially in the waiting room. This study aims to determine the thermal conditions of the design of ventilation using the theory of Mom and Wiseborn, SNI 03-6572-2001, and Olgyay chart. This research method uses quantitative and field measurements were done for 14 hours to know the movement of air, temperature, humidity. The results were then compared with the standard and the theory. It was found that thermal comfort conditions that still utilize the movement of the wind from natural ventilation in the main waiting room of Tawang Semarang Station.Keyword: Thermal Condition, Natural Ventilation, Semarang Tawang Station.Abstrak: Kenyamanan termal merupakan suatu kondisi pikir seseorang yang mengekspresikan kepuasan pengguna terhadap kondisi termal.  Penelitian ini berfokus pada desain penghawaan yang merupakan salah satu upaya mengurangi panas yang ada dalam bangunan terutama dalam menjaga kondisi termal. Stasiun Tawang Semarang, mempunyai desain penghawaan alami yang masih dipertahannkan terutama pada ruang tungguya. Penelitian ini  bertujuan untuk mengetahui kondisi termal dari desain penghawaan dengan menggunakan teori mom dan wiseborn, SNI 03-6572-2001, serta grafik olgyay. Metode penelitian ini menggunakan kuantitatif dan pengukuran dilapangan dilakukan selama 14 jam untuk mengetahui pergerakan udara, temperature, kelembaban. Hasil penelitian kemudian di bandingkan dengan standar SNI, Mom & Wiseborn dan Diagram Olgyay. Ditemukan bahwa kondisi kenyamanan termal yang masih memanfaatkan pergerakan angin dari ventilasi alami pada ruang tunggu utama Stasiun Semarang Tawang.Kata Kunci: Kondisi Termal, Ventilasi Alami, Ruang tunggu, Stasiun Semarang Tawang
Dimensi Sosial Budaya Bagi Keragaman Praktik Perawatan Kesehatan Penderita Malaria di Topoyo Provinsi Sulawesi Barat
Authors: Kadir Yahya -
Published: December 2018

The aim of the research was to describe and get understanding on health care practiced by community members infected or indicated infected by malaria in Topoyo District, Central Mamuju Regency, West Sulawesi Province. Using ethnographic approach, data was obtained through observation and in-depth interview. The study indicates that the community members infected or indicated infected by malaria not only to practice health care in various ways in overcoming malaria but also to mix the elements of treatment techniques derived from scientific medical tradition and local medical tradition. The variety and mixture of the health treatment is conditioned by the assumption that all types of medicines are powerful to cure illnesses. The cure of illnesses is determined by the compatibility of the drug and the blessing of God as the primary cause for the occurrence and cure of illnesses. It is also affected by different understandings, experiences, and information networks on malaria that are accessed by each actor and the attitude to respond illness.
KHAZANAH NASKAH KEAGAMAAN DI PAMEKASAN MADURA
Authors: Ridlo Subkhan
Published: December 2018

Naskah keagamaan di Pamekasan Madura, terutama yang tersimpan di masyarakat, kurang mendapat perhatian, baik dari pemiliknya ataupun dari pemerintah. Khazanah naskah tersebut banyak yang tak terawat sehingga
naskah
banyak yang rusak akibat dimakan serangga ataupun cuaca. Seperti yang terjadi pada beberapanaskah di Jambul, Banyumas, Taposan, Sumber Anyar dan  Pangereman. Tidak jarang naskah Pamekasan-Madura tersebut dijual-belikan karena faktor ekonomi, atau kurangnya pengetahuan akan nilai naskah yang mengandung sejarah masa lampau. Oleh karena itu penelitian ini fokus pada upaya inventarisasi naskah keagamaan di Pamekasan Madura, dengan menggunakan metode filologi  dan kodikologi, yang tujuannya adalah mendeskripsikan khazanah naskah tersebut. Naskah keagamaan di Pamekasan Madura berjumlah 124 yang berada di sembilan tempat. Kesemua naskah tersebut diperkirakan ditulis pada abad 18. 
IMPLEMENTASI PEMBELAJARAN PENDIDIKAN AGAMA ISLAM DI INSTITUT TEKNOLOGI BANDUNG
Authors: Saepudin Juju
Published: December 2018

Dampak negatif dari kemajuan ilmu pengetahuan dan teknologi serta lajunya arus modernisasi yang begitu cepat, menuntut umat manusia untuk segera� membentengi diri dengan kemampuan kepribadiannya agar tidak kehilangan jati diri serta ikut terseret dalam pola globalisasi yang jauh dari nilai-nilai agama. Pendidikan agama dipandang memiliki peranan yang sangat vital dalam membangun watak dan peradaban bangsa yang bermartabat sebagi solusi mengatasi hal tersebut. Untuk itu diperlukan pelaksanaan pendidikan agama yang lebih kondusif dan prospektif terutama di perguruan tinggi yang merupakan garda terdepan dalam mengantisifasi perubahan. Tulisan ini menyajikan model implementasi pembelajaran Pendidikan Agama Islam (PAI) di Institut Teknologi Bandung (ITB). Metode pengumpulan data dengan observasi, wawancara mendalam dan dokumentasi. Hasil analisa data secara induktif dapat diketahui bahwa� implementasi PAI di ITB dilakukan dengan mengacu kepada Sistem Pendidikan Nasional yang dikembangkan melalui program pembelajaran berupa� character buiding yang dilakukan� secara sinergi antar Sosio-Teknologi ITB, Yayasan Masjid Salman ITB dan UKM Gamais ITB. Implikasi dari hal tersebut di atas mampu membentuk sosok mahasiswa yang memiliki karakter, watak dan kepribadian serta prestasi yang disertai prestise dengan landasan keimanan dan ketakwaan serta nilai-nilai akhlak di masyarakat
O NOVO CÓDIGO DE PROCESSO CIVIL COLOCADO EM PRÁTICA: PERCALÇOS E DESAFIOS INICIAIS
Authors: Ramos Carlos Henrique , Mousinho Isabel Ribeiro
Published: December 2018

A aprovação do Novo Código de Processo Civil despertou inúmeros debates no seio doutrinário, especialmente por inaugurar um paradigma processual cooperativo e pautado nos direitos fundamentais. Neste cenário, o presente estudo objetiva apresentar ao leitor um panorama de todo o contexto histórico das reformas processuais no sistema nacional, as principais modificações implementadas e os desafios e percalços identificados nos primeiros meses de vigência do novo diploma.
MEDIAÇÃO JUDICIAL NO BRASIL: BREVES NOTAS CONCEITUAIS À LUZ DE PRINCÍPIOS CONSTITUCIONAIS
Authors: Santos Tânia Maria dos
Published: December 2018

A utilização da expressão “mediação judicial” pode ser considerada um indicador da problemática que, no presente trabalho, se propõe a investigar e construir pontes conceituais entre uma atividade, a mediação, que tende a ser mais prática com outra, e a judicial, que é mais técnica e teórica. A mediação é apresentada como um caminho que facilita, ou restabelece a capacidade de diálogo sobre situações conflituosas entre pessoas, grupos ou organizações. Para tanto, será distinguida a mediação judicial de outros meios alternativos, Resoluções Adequadas de Disputas (RAD), serão particularizados papéis de advogados, juízes e mediadores diante do avançado instrumento jurídico pátrio, e examinará alguns princípios. Ao fim da pesquisa, contempla-se que a mediação judicial, como fio condutor democrático, tem base em direitos fundamentais dos quais foram desprendidos os do acesso à justiça e o da solidariedade, pois o escopo desses princípios é levar o cidadão a sério e fortalecer a civilidade na sociedade.
O AFETO COMO DIFERENCIAL NAS RELAÇÕES FAMILIARES: UM CONVITE À MEDIAÇÃO COMO MEIO ADEQUADO DE RESOLUÇÃO DE CONFLITOS
Authors: Oliveira Glenda Felix
Published: December 2018

A família passou por uma série de transformações ao longo dos anos, deixando para trás o caráter meramente biológico e passando a se apoiar em novas bases. Atualmente, a família deve ser compreendida como um grupo social que se baseia em torno de laços afetivos. Em razão dessa nova moldura, surgiu o desafio de estabelecer formas para a resolução de conflitos decorrentes dessas relações. Diante disso, este artigo teve o objetivo de, por meio da pesquisa bibliográfica, apontar as peculiaridades das relações familiares, contemplando o afeto como seu traço diferencial. Teve ainda a ambição de compreender a mediação como a forma mais adequada para a resolução de tais conflitos. O método escolhido foi o jurídico-sociológico, que nos levou a constatar que a mediação deve ser estimulada nas ações familiares, por conseguir trabalhar de forma técnica com fatores tão subjetivos. O afeto, como base das relações familiares atuais, merece tratamento adequado dentro e fora do judiciário.
CONTROLE BIOLÓGICO DE FORMIGAS-CORTADEIRAS: O CASO DA PREDAÇÃO DE FÊMEAS DE Atta SPP. POR Canthon virens
Authors: Araújo Márcio da Silva , Rodrigues Camila Alves , Oliveira Marco Antônio de , Jesus Flávio Gonçalves de
Published: December 2018

As formigas-cortadeiras são importantes pragas dos setores agrícola e florestal do Brasil. O controle dessa praga, em geral, tem sido realizado com uso de inseticidas químicos, especialmente iscas formicidas envenenadas. Formas alternativas ao controle químico são conhecidas e podem representar significativo controle dessa praga, entretanto são pouco estudadas. O propósito deste texto é discorrer sobre aspectos bioecológicos e perspectivas de uso de um característico predador de fêmeas de Atta Fabricius, 1804 (Hymenoptera: Formicidae), o besouro predador Canthon virens Mannerhein (1929) (Coleoptera: Scarabaeidae). Esse predador, comumente encontrado em áreas de cerrado do Brasil, decapta as fêmas de saúvas assim que elas aterrizam ao solo pós voô nupcial ou revoada. Essa presa abatida é transportada para o interior de seus ninhos construídos no solo e servirá de alimento para as suas larvas.
KAJIAN MORFOLOGIS TUTURAN ANAK USIA 5 TAHUN
Authors: Anam Samsul , Awalludin Awalludin
Published: December 2018

Tujuan penelitian ini adalah untuk mendeskripsikan bentuk-bentuk dan makna  proses morfologis yang muncul dari tuturan anak usia 5 tahun.  Metode yang digunakan adalah metode deskriptif dengan teknik pengumpulan data berupa teknik observasi, yang didukung oleh teknik catat, dan teknik rekam. Dari hasil penelitian dapat disimpulkan bahwa proses morfologis yang dihasilkan oleh tuturan anak usia lima tahun meliputi proses afiksasi, proses reduplikasi, serta proses komposisi, dan makna dari proses tersebut terdiri dari tiga yaitu makna proses afiksasi, makna proses reduplikasi, dan makna proses komposisi. Penelitian terkait pemerolehan kebahasaan pada anak adalah hal yang unik dan menarik untuk dikaji. Oleh karena itu, penelitian-penelitian berikutnya dengan cakupan yang lebih luas sangatlah diharapkan, sehingga diperoleh informasi yang lebih mendalam dan lebih lengkap.
IoT in Agriculture : Smart Farming
Authors: S. Kanchana
Published: December 2018

From farm to fork, information and communication technology sector is being enhanced to facilitate the farmers, croppers and related users of intelligent services. Technological revolution integrates the development of smart devices and IoT services. To feed the ever growing global population, the agriculture industry needs to be extended. Internet of Things opens the door wide for smart farming solution to increase the agricultural production. IoT technologies helps the farmers as a service by providing historical and real time data for predicting soil quality, weather conditions and crop’s health. Smart farming provides the enhanced facility for process automation and evaluation and waste reduction. As a result, all these factors drastically increase the quality and quantity of the food products and decrease the production cost. This paper outlines the promising solutions applied in the sphere of agriculture.
A Case Study : Security as A Service (SAAS) in Cloud Computing Environment
Authors: A Vivekanand , Singh Randhawa Trilok
Published: December 2018

Security-as-a-service (SaaS) is an outsourcing model for security management in cloud computing environment. The researcher focused on the some of the significant research issues in cloud computing typically, Security as a Service involves applications on AMAZON online shopping portal and its controlling mechanism in cloud computing environment. Outsourcing of administrative tasks, such as log management, to save time and money and allow an organization to devote more time to its core competencies. A Web interface that allows in-house administration of some tasks as well as a view of the security environment and on-going activities. The researcher proposed a model as applied to information security type services and does not require on-premises hardware, avoiding substantial capital outlays. These security services often include authentication, anti-virus, anti-malware/spyware, intrusion detection, and Penetration testing and security event management, among others.
Getting Started with Time-Use Dat
Authors: Stewart Jay
Published: December 2018

Time-use data have unique characteristics that make it different from other types of household survey data. Single-day time use surveys provide a detailed snapshot of a person’s activities on the diary day. But the large amount of day-to-day variation in the amount of time spent in various activities means that activities done on the diary day do not reflect the person’s long-run time use. Thus, time-use data is a sample of person-days, not a sample of people. This feature of time-use data has implications for its analysis.
Discretionary Time Over Time: A Longitudinal View of Adults’ Lives and Leisure
Authors: Carpenter Gaylene , Stockard Jean
Published: December 2018

This study examined how middle-aged adults perceive discretionary or free time in their lives and the ways in which their life experiences and reflections on life structure are related to these perceptions. Research focused specifically on how changes in perceptions of available discretionary time were related to changing life experiences, assessments of life structure, and perceptions regarding leisure over a nine-year period. Data came from the longitudinal investigation of leisure, life perceptions, and life values: A Study of Leisure During Adulthood, ASOLDA. Descriptive statistics and mixed models were used to examine longitudinal quantitative data from eighty-four study participants. Results indicated that perceptions of time scarcity were most common for adults in years in which they had experienced more negative life events, especially when these life experiences prompted them to rethink and re-evaluate their lives. This pattern was most marked for those who had more positive perceptions of leisure. Data from four qualitative case studies further illustrate findings and future theoretical directions are discussed.
Pursuing a targeted dream specialty and a research career: Opinions and observations from a fifth-year medical student’s
Authors: Tawfik Gehad Mohamed
Published: December 2018

With our fast-pacing life, numerous learning and scientific sources and information are available and required for medical students to boost their skills since their early life to accommodate with great knowledge they take. Medical students should re-elaborate what they studied and exploit knowledge clinically. A good doctor is a good observer, so eyes should be kept on while mentor managing patients in order to add more to our medical notions. A seed to become a great future doctor starts by searching for specialty that fits your personality, to practice it as a volunteer, to gain its skills earlier. So when you graduate, you have more time to gain other learning experience. As long as you practice it, the more chance to become one of its experts. Managing your patient as a relative, not as a bag of money, is very important to be applied. Inability to diagnose a patient is not a shame, so never let a patient go home without referring him to another doctor who has more experience than you. Having a background in other medical specialties will help you recognize common signs of other related medical conditions that could lead you to refer him to right specialty doctor. Joining a research lab will keep you updated with new inventions, drugs, algorithms, and guidelines, which will help you become more acknowledged with medical problems that you were unaware of. Time management is the key to success as a researcher without affecting your daily life activities and study requirements.
Directed Acyclic Graphs: Alternative tool for causal inference in epidemiology and biostatistics research and teaching
Authors: Dang Tran Ngoc , Long Khuong Quynh , Tram Huynh Thi Hong , Hong Le Huynh Thi Cam , Tuan Vo Minh
Published: December 2018

The issue of causation is one of the major challenges for epidemiologists who aim to understand the association between an exposure and an outcome to explain disease patterns and potentially provide a basis for intervention. Suitably designed experimental studies can offer robust evidence of the causal relationships. The experimental studies, however, are not popular, difficult or even unethical and impossible to conduct; it would be desirable if there is a methodology for reducing bias or strengthening the causal inferences drawn from observational studies. The traditional approach of estimating causal effects in such studies is to adjust for a set of variables judged to be confounders by including them in a multiple regression. However, which variables should be adjusted for as confounders in a regression model has long been a controversial issue in epidemiology. From my observation, the adjustments using only “statistical artifacts” methods such as the p-value<0.2 in univariate analysis, stepwise (forward/backward) are widely used in research and teaching in Epidemiology and Statistics but without appropriated notice on the biological or clinical relationships between exposure and outcome which may induce the bias in estimating causal effects. In this mini-review, we introduce an interesting method, namely Directed Acyclic Graphs (DAGs), which can be used to reduce the bias in estimating causal effects; it is also a good application for Epidemiology and Biostatistics teaching.
Effect of fluid bolus triggers and their combination on fluid responsiveness in optimization phase of severe sepsis and septic shock resuscitation
Authors: Bien Le Huu Thien , Dai Huynh Quang , Tuan Mai Anh , Minha Phan Vu Anh , Thao Pham Thi Ngoc , Huy Do Quoc , Tuan Vo Minh , Phuoc Dang Van
Published: December 2018

to evaluate the fluid responsiveness according to fluid bolus triggers and their combination in severe sepsis and septic shock.

observational study.

patients with severe sepsis and septic shock who already received fluid after rescue phase of resuscitation. Fluid bolus (FB) was prescribed upon perceived hypovolemic manifestations: low central venous pressure (CVP), low blood pressure, tachycardia, low urine output (UOP), hyperlactatemia. FB was performed by Ringer lactate 500 ml/30 min and responsiveness was defined by increasing in stroke volume (SV) ≥15%.

84 patients were enrolled, among them 30 responded to FB (35.7%). Demographic and hemodynamic profi before fluid bolus were similar between responders and non-responders, except CVP was lower in responders (7.3 ± 3.4 mmHg vs 9.2 ± 3.6 mmHg) (p 0.018). Fluid response in low CVP, low blood pressure, tachycardia, low UOP, hyperlactatemia were 48.6%, 47.4%, 38.5%, 37.0%, 36.8% making the odd ratio (OR) of these triggers were 2.81 (1.09-7.27), 1.60 (0.54-4.78), 1.89 (0.58-6.18), 1.15 (0.41-3.27) and 1.27 (0.46-3.53) respectively. Although CVP < 8 mmHg had a higher response rate, the association was not consistent at lower cut-offs. The combination of these triggers appeared to raise fluid response but did not reach statistical signifi 26.7% (1 trigger), 31.0% (2 triggers), 35.7% (3 triggers), 55.6% (4 triggers), 100% (5 triggers).

fluid responsiveness was low in optimization phase of resuscitation. No fluid bolus trigger was superior to the others in term of providing a higher responsiveness, their combination did not improve fluid responsiveness as well.
Antitumor-Promoting Effect of Ethanolic Extract from Leaves of Perilla frutescens var. crispa (Benth.) In Mouse Skin
Authors: Quyen Vuu Thanh Tu , Thuy Huynh Ngoc , Hien Ha Minh , Trinh Huynh Ngoc
Published: December 2018

This study aimed to investigate the antitumor-promoting effects of total ethanolic extract from Perilla leaf (PLE) in a two-stage chemical carcinogenesis protocol in mice. Quantitative analysis active compounds in PLE were performed by thin layer chromatography with normal phase of silica gel F254 and HPLC-PDA with reversed phase of C18 column at UV 300 nm. The cutaneous tumors were initiated by a single application by 7,12-dimethylbenz[a]anthracene (DMBA) on the dorsal shaved skin, then promoted by repeated applications of croton oil during 20 weeks. PLE was topically applied daily until the end of the experiment. The results observed from thin layer chromatogram highlighted the presence of rosmarinic acid and luteolin in PLE. By means of HPLC-PDA analysis, the total content of rosmarinic acid and luteolin were found in amounts of 1.178 ± 0.011 % (w/w) and 0.105 ± 0.001 % (w/w), respectively. The PLE-treated group prolonged the latency period of tumor appearance up to 2 weeks and also signifi reduced tumor volume in dorsal skin of mice as compared to untreated group. In conclusion, the total ethanolic extract from leaves of Perilla frutescens demonstrated promising antitumor-promotion activity in mouse skin.
Association of B-Type Natriureteric Peptide Levels With Estimated Glomerular Filtration Rate in Different Stages of Chronic Kidney Disease And Relevant Echocardiographic Changes
Authors: Mahmood Nazneen , Rahman M Muhibur , Huq KMSH Sirazul , Hassan Md Mahtabuddin , Siddiqui Md Mahmudur Rahman , Giasuddin Rubayat Sheik , Mahmood Farhana , Shumi Shamima Islam
Published: December 2018

Background: B-type natriuretic peptide (BNP) is a biomarker of cardiovascular disease that is common in patients with chronic kidney disease (CKD). The influence of glomerular filtration rate (GFR) on BNP in CKD may stem from failure to account fully for the effects of coexistent cardiac disease, dysfunction and volume overload.Material & Methods: This is a cross sectional descriptive type of observational study conducted by the Department of Nephrology of Anwer Khan Modern Medical College Hospital during the period of Jan 2016 to Dec 2016.Results: A total number of 71 patients were included in the study. Out of them 42(59.15%) were male and 29(40.85%) were female with a M:F of 1.45:1. The mean age of the patients was 62.54+13.92 years (Range 18- 90 years). Mean e GFR was 21.81+15.01 ml/min/1.73 body surface area, mean Serum Creatinine was 5.04+3.29 mg/dl, mean Hb% was 10.90+1.5 gm/dl and that of BNP was 1335.03+1838.43 Pg/ml and that of Ejection Fraction (EF) was 50.05+12.61%. 21.12%(15) were on Stage 3 CKD(Chronic Kidney Disease) and 33.80% (24) and 45.08%(32) were on Stage-4 and Stage-5 respectively.There was a strong and highly significant inverse association between BNP and e GFR (p<0.001), with higher BNP level observed in those with lower eGFR. BNP is directly proportional to Serum Creatinine which is significant (p<0.001). BNP rises as Serum Creatinine rises. Regarding echocardiographic changes, almost all the patients 69(97.18%) had Left ventricular hypertrophy (LVH). 24(33.80%) had Left ventricular (LV) diastolic dysfunction, 19(26.76%) had LV systolic dysfunction and dilated LV and rest of them 28(39.44%)had good biventricular function. 35 (49.29%) patients had mild pericardial effusion(PE) and 39(54.92%) had hypokinesia in different cardiac wall. Most of the patients 65(91.54%) had mild mitral regurgitation (MR), tricuspid regurgitation (TR), aortic regurgitation (AR).Conclusion: Our goal was to provide compelling evidence of the association of renal function and BNP, with the full expectation that additional prospective studies will be required to validate and better define this relationship. Ideally, clinicians need clear guidelines regarding BNP and heart failure that include consideration of eGFR. Currently most institutions, including our own, continue to use BNP cutoff diagnostic levels that have not been adjusted for eGFR. Our data emphasized that a single BNP measurement must be evaluated in conjunction with the entire clinical presentation, particularly the level of renal failure.Anwer Khan Modern Medical College Journal Vol. 9, No. 2: Jul 2018, P 85-90