bluuebunny/crossref_metadata_2025 huggingface dataset:
Anticancer effect of a combination of cisplatin and matrine on cervical cancer U14 cells and U14 tumor-bearing mice, and possible mechanism of action involved
Authors: Yang Aihong , Zhu Jun , Xu Feixue , Yang Jiao , Wang Ying , Wei Min , Bai Xuefei , Yang Yongxiu
Published: March 2022

Purpose: To investigate the anticancer effects of cisplatin (DDP) in combination with matrine on cervical cancer U14 cell tumor-bearing mice.

Methods: The cell proliferation of cervical cancer U14 cells treated with DDP (25, 20, 15, 10 and 5 μg/mL); matrine (2.5, 2.0, 1.5, 1.0 and 0.5 mg/mL); or DDP (15 μg/mL) + matrine (2.5, 2.0, 1.5, 1.0 and 0.5 mg/mL) was determined with MTT assay. The anticancer effect of DDP + matrine in U14 tumor-bearing mice was also investigated, based on expression of tumor suppressor lung cancer 1 (TSLC1) using quantitative real time-polymerase chain reaction (qRT-PCR) and immunohistochemistry.

Results: The inhibition of proliferation of U14 cells ranged from 26.68–70.25, 10.20–61.73, and 51.89–89.75 % for DDP, matrine and DDP + matrine, respectively. In mice with U14 solid tumors, the DDP group had 12.3 % weight loss (p < 0.05). Treatment with DDP, matrine, and DDP + matrine reduced tumor growth by 64.56, 42.22–56.67, and 67.78–81.11 %, respectively (p < 0.01). Results from RT-qPCR and immunohistochemistry showed corresponding increases in expression levels of TSLC1.

Conclusion: These results indicate that the anticancer activity of DDP + matrine is higher than that of a single treatment with either DPP or matrine. The likely mechanism of action might be related to promotion of TSLC1 expression. This finding provides a potential strategy for the management of cervical cancer.
Erdosteine prevents contrast-induced renal oxidative stress damage in mice
Authors: Zhou Qiwei , Qian Feng , Jia Zhuo , Zhang Xu
Published: March 2022

Purpose: To investigate the protective effect of erdosteine on contrast-induced renal oxidative stress in mice.

Methods: C57BL/6 mice were injected intraperitoneally with contrast medium to establish an acute kidney injury model (AKI). Renal function, blood urea nitrogen (BUN) and serum creatinine (SCr) were determined. Also, oxidative stress, lactate dehydrogenase (LDH), malondialdehyde (MDA), superoxide dismutase (SOD) and reduced glutathione (GSH) were evaluated. And the renal tissue structure was examined by light microscopy, while Western blot (WB) and Real-time polymerase chain reaction (RT-PCR) were used to determine the expressions of senescence-related factor, Nrf-2 and downstream antioxidant factor.

Results: Erdosteine improved the renal structure of mice and significantly decreased serum BUN and SCr levels. In addition, erdosteine promoted the expression of antioxidant enzymes SOD1, SOD2, GPX1 and GPX3 in renal tissues, decreased the content of ROS, and inhibited the content of LDH and MDA in serum. Also, WB and RT-PCR results showed that erdosteine activated Nrf2 pathway, thereby alleviating contrast-induced renal injury.

Conclusion: Erdosteine inhibits contrast-induced renal oxidative stress in mice and delays cell senescence by activating Nrf2 pathway. This will be of great significance in the treatment of contrast-induced nephropathy.
Drug cost optimization of cholinesterase inhibitor therapy in advanced dementia: Results of a prospective study of discontinuation
Authors: Garcia-Garcia Ramon R. , Calleja-Hernandez Miguel Angel M.A.
Published: March 2022

Purpose: To investigate the effect of discontinuing treatment with cholinesterase inhibitors (ChEIs) on drug costs in patients with advanced dementia.

Methods: Severe dementia patients receiving ChEI treatment for over 12 months (n = 43) aged over 65 years (mean age = 82.6 ± 7.5 years) were recruited from 8 nursing homes located in Alicante, Spain. ChEI treatment was discontinued in 23 patients. Here, we report the results from a cost-minimization analysis to evaluate the drug costs with a follow-up period of three months. The drug costs were prospectively analyzed based on drug acquisition costs.

Results: At the end of the follow-up, the mean monthly drug costs were €52.68 ± 22.48 in the discontinuation group and €122.54 ± 44.74 in the continuation group - a significant difference of means of -€69.86 (95 % CI, -91.24 to -48.48; p = 0.000). The monthly drug cost reduction for the ChEI discontinuation group was €1,533.35.

Conclusion: ChEI discontinuation appears to be a possible option for minimizing treatment costs in institutionalized patients with advanced dementia.
LncRNA NBAT-1 inhibits the progression of hepatocellular carcinoma by interacting with CYLD
Authors: Sun Jisan , Li Guoyao , Zhang Li , Xie Yan , Chen Chiyi , He Jian , Jiang Wentao
Published: March 2022

Purpose: To illustrate the biological influences of long non-coding RNA (lncRNA) NBAT-1 (neuroblastoma associated transcript 1) on HCC progression and the molecular mechanism of action.

Methods: NBAT-1 levels in HCC tissues and cell lines were determined by quantitative real-time polymerase chain reaction (qRT-PCR). The relationship between NBAT-1 and prognosis in HCC was analyzed. After knockdown of NBAT-1 in HepG2 and Hep3B cells, proliferative and migratory changes were assessed by cell counting kit-8 (CCK-8) and Transwell assay, respectively. The interaction between NBAT-1 and CYLD was confirmed by subcellular fraction determination and RNA binding protein immunoprecipitation (RIP). Rescue experiments were conducted to verify the involvement of CYLD in HCC cell functions regulated by NBAT-1.

Results: NBAT-1 was downregulated in HCC tissues. Its level was much lower in metastatic or advanced stage HCC patients (p < 0.05), showing a certain prognostic potential. Knockdown of NBAT-1 stimulated proliferative and migratory potentials in HepG2 and Hep3B cells. NBAT-1 was mainly distributed in the cell cytoplasm. The mRNA and protein levels of CYLD were downregulated in HCC cells by NBAT-1 knockdown, displaying a positive interaction. CYLD was involved in the regulatory effect of NBAT-1 on HCC progression.

Conclusion: Through a positive interaction with CYLD, NBAT-1 inhibits the malignant progression of HCC. These findings provide a potential approach to the development of targeted therapies for HCC.
Heno molido de gramínea johnson y adición de heno largo en raciones completamente mezcladas para vacas lecheras
Authors: Rafael Acevedo-Rosario  , Paul F. Randel
Published: March 2022

Se compararon dos raciones completamente mezcladas (TMR), que incluyeron 20% de heno molido, ya sea de gramínea Johnson (J) o de pajón y estrella (PS); ambas raciones incluyeron 20% de heno PS picado grueso y 60% de concentrados, con un contenido aproximado de 13% de proteína bruta. Los tratamientos I y II consistieron de TMR-J sin y con la adición de 1.5 kg por cabeza de heno PS largo; III y IV consistieron de TMR-PS sin y con dicha adición, respectivamente ( 2 x 2 factorial). Se ofreció el alimento solamente durante el intervalo entre el ordeño vespertino y el matutino. Participaron 10 vacas Holstein adultas, confinadas en dos grupos de tres vacas y dos grupos de dos vacas, en un experimento de diseño cuadrado latino 4 x 4, con períodos comparativos de dos semanas. No se detectó ninguna interacción significativa entre factores de tratamientos. Las medias comparativas de los efectos de TMR-J contra TMR-PS, y la no adición contra la adición de heno largo fueron: ingestión diaria de materia seca (DMI), 19.89 vs. 19.65 y 19.76 vs. 19.77 kg; producción diaria de leche, 18.46 vs. 18.89 y 18.48 vs. 18.87 kg; porcentaje de grasa láctea, 2.64 vs. 2.71 y 2.60 vs. 2.76; eficiencia alimentaría (leche corregida a 4% grasa/DMI), 0.736 vs. 0.777 y 0.741 vs. 0.772, respectivamente. La adición de heno largo aumentó el contenido de grasa por 0.16%, mientras TMR-PS superó a TMR-J en eficiencia por 0.041 (P < 0.05). La media general de temperatura rectal (RT), poco después de mediodía, fue 39.8 ± 0.3°C (desviación estándard, DE) y la de peso vivo, 590 ± 43 kg (DE). No hubo relación entre la producción de leche y la RT. Se concluye que el heno de gramínea johnson resultó satisfactorio en las TMR, que la adición de heno largo incentivó el porcentaje de grasa láctea y que la alimentación limitada a las horas de ambiente fresco ayudó a mitigar la hipertermia animal.
COMPORTAMIENTO DE CULTIVARES DE CEBOLLA DE DÍAS INTERMEDIOS EN EL SUR DE PUERTO RICO
Authors: Irma Cabrera-Asencio
Published: March 2022

COMPORTAMIENTO DE CULTIVARES DE CEBOLLA DE DÍAS INTERMEDIOS EN EL SUR DE PUERTO RICO
EVALUACIÓN DE DOCE GENOTIPOS DE CHINA (CITRUS SINENSIS) EN DOS PATRONES
Authors: Félix M. Román  , Carlos Flores  , Gerardo Ruiz-Sifre
Published: March 2022

EVALUACIÓN DE DOCE GENOTIPOS DE CHINA (CITRUS SINENSIS) EN DOS PATRONES
INSECTOS PRESENTES EN CULTIVARES COMERCIALES DE BRASSICA OLERACEA G. ITÁLICA (L.) EN DIFERENTES ÁREAS DE PUERTO RICO
Authors: Irma Cabrera-Asencio  , Sonia Martínez  , Essaú Orengo
Published: March 2022

INSECTOS PRESENTES EN CULTIVARES COMERCIALES DE BRASSICA OLERACEA G. ITÁLICA (L.) EN DIFERENTES ÁREAS DE PUERTO RICO
Comparative Study of Design of Over Head Water Tanks for Capacity of 100 kL to 300 kL using Recent Past IS 3370
Authors: Chandra Mahesh , Kumar Baghel Rajendra , Binnani Nikunj
Published: March 2022

An elevated reservoir is mostly used to store, liquid products like water, petroleum, and other types of chemicals, which require some static head to provide kinetic energy for flow. Except for the durability aspect, design load calculation of various reservoirs is similar regardless of the chemical aggressiveness. In general, water-retaining structures have been designed as crack-free structure to avoid any sort of outflow. As per the observation from the field, the overhead water tanks were designed continuously using the old Indian Standard codes (IS 3370: 1965 (Part 1 to 2), IS 1893: 1984 (Part 1) and IS 875: 1987 (Part 3)). In order to understand the variation in design due to amendments in Indian Standard (IS 3370: 2021 (Part-1 to 2), IS 1893: 2014 (Part-2), IS 875: 2015 (Part-3) in past few years, it is necessary to do comparative study of design of elevated reservoirs for different capacity. This study is an attempt to compare the design provisions based on different design philosophies i.e. WSM (IS: 3370 (1965) and LSM (IS: 3370 (2021). In this paper, variation in reinforcement quantity in different elements of double domed elevated reservoir has been estimated for 100 kL to 300 kL capacity for seismic zone-III and for wind speed 39 m/sec. A design program has been prepared for the design calculations of overhead water tanks using MS excel for different capacity and distinctive IS codal provisions. Comparison of results using different design philosophies has raised the need for retrofitting of various elements of existing water tanks.
Federalismo mexicano: gobierno dividido en la Cuarta Transformación
Authors: Pérez Ramírez Rigoberto
Published: March 2022

En los últimos 30 años la pluralidad política en gobiernos divididos ha ganado espacios en el federalismo mexicano poniendo énfasis la cooperación de la rama legislativa mediante el establecimiento de negociaciones intra-parlamentarias e inter-gubenamentales para no generar parálisis a pesar de la confrontación de poderes. El objetivo principal de este trabajo es estudiar el federalismo mexicano a partir del gobierno dividido en la “Cuarta Transformación” para explicar los acuerdos institucionales en la agenda legislativa. Para ello, se emplea el método descriptivo-analítico que en la narrativa de la información documental y estudios empíricos fundamenta los cambios graduales de carácter institucional que ha experimentado el régimen político mexicano y cómo estos han llevado a una composición bicameral sin mayorías y gobiernos divididos, pero que en el arte de la política han logrado consensos y acuerdos para la aprobación de leyes, reformas constitucionales y la creación de nuevas instituciones, en el sentido de equilibrar el régimen federal, fortalecer el diseño de políticas públicas y la democracia. La estrategia política de conformación de coaliciones que favorezcan la aprobación de las iniciativas de reformas que propone el Ejecutivo ha sido un continuum de los gobiernos divididos desde su aparición en 1997; sin embargo, la polarización ideológica que generan las iniciativas de reforma del Ejecutivo con la alianza opositora “Va por México” puede afectar el rumbo del país, aunque habrá que esperar un tiempo adecuado para conocer la efectividad de los nuevos arreglos institucionales en el diseño de políticas públicas.
TATUAR O TABU, OU INCARNAR UMA VESTIMENTA
Authors: Mineiro Daniel , Pinto Paulo Mendes
Published: March 2022

Na tradição ocidental existe uma estrutura religiosa muito específica e desenraizada do corpo. A par dela, surgiu uma antropologia e sociologias do corpo, que imprimiam etiquetas, normas e modos de encarar o corpo e a identidade. Face a esta tormenta, os atuais modos de enquadrar o corpo apontam para uma fenomenologia da dor, como forma de libertação do sujeito e consecutiva realização espiritual e identitária. É a partir de uma apropriação de si, através de uma perceção fina do corpo, que nasce uma nova forma de “vestir” o corpo com uma imagética, que não pode deixar de dever a nova Era Digital.
SIMULASI RANGKAIAN SEVEN SEGMENT MENGGUNAKAN MULTISIM PADA PEMBELAJARAN RANGKAIAN ELEKTRONIKA ANALOG DAN DIGITAL DI SMKS INFORMATIKA SUKMA MANDIRI
Authors: Surahmat Ahmad , Fu’ady Tb Dedy
Published: March 2022

Electronic components are the most complex and sensitive components, not infrequently damage occurs if the components used are not appropriate, for example, excess power, current, short and others. Therefore simulation software can help the process of designing electronic circuits before being patented directly on the components. Not only that, we can also use electronic devices that we cannot reach (buy and meet) like the oscilloscope in the simulation software. The use of a simulation device is used one of them to build a concept in terms of teaching and learning. NI Multisim 11.0 software can be used in the teaching and learning process in this case is the subjects of a series of analog and digital electronics on the seven segment material. Seven segment is a display that is formed from 7 groups of LED (Light Emitting Diode) segments that function to emit light when passing through an electric current through which it is arranged in such a way as to form numbers from 0 (zero) to 9 (nine). Where in this simulator there is a simulation that shows the process of the formation of hex numbers as output. This research discusses how to design schematic circuits, analyze, simulate, check errors, and make layouts on a PCB. The results of this study concluded that the use of Multisim NI software is very good for learning media so that the material presented will be easier to understand.
SISTEM INFORMASI DATA ATLET PADA KONI PROVINSI BANTEN
Authors: Romdoni Mochamad Yusuf , Ruhiawati Irma Yunita
Published: March 2022

KONI (Indonesian National Sports Committee) Banten Province is an organization that acts as the parent in the field of sports that continues to foster outstanding athletes from several categories at the local, national, and international levels. In the world of sports, Koni plays an important role in cultivating and fostering athletes. To determine qualified athletes from various categories so that they are ready to take part in a sporting event can be seen from their physical condition and achievements. In this athlete's recommendation must go through the calculation stages manually from physical records, achievements and all trainers who understand it. To solve this problem, we need a system to help process athlete data from several categories which are then used as recommendations for athletes who are ready to be included in an event. Athlete data information systems are built on the basis of assisting in athlete data processing to be more effective and faster, this system is designed with the Waterfall development method in which the program flow design uses Flowcharts so that it becomes clearer how the athlete's information system can run according to good data processing mechanisms from the start of input, process and output. The programming language used is a visual basic language that has been popular and has proven its ability in handling data processing, which on this occasion the database is MySQL. This information system is certainly not immune to weaknesses whose hopes for the future to continue to be developed in order to continue to be useful and easy to operate.
ANALISA PERANCANGAN SISTEM INFORMASI PENDAFTARAN MAGANG KERJA MENGGUNAKAN WATERFALL
Authors: Fuady Tb Dedy , Suhendar Benny
Published: March 2022

The development of technology and communication greatly helps the performance and business processes of an organization. Its development must result in benefits for the organization in obtaining information, as well as assisting the organization in carrying out the required business processes so as to help organizational managers make decisions. Changes in the form of business processes that are used with the development of technology and communication are expected to be able to encourage organizations to have better management. The management of this Field Work Apprenticeship activity still uses manual methods in some of its business processes, so that the benefits of technological developments and communication are not used. Researchers assess and consider the need to develop an information system for Field Work Apprenticeships using the Waterfall method. The test results show that the system is able to carry out the Field Work Apprenticeship business process easily without having to use manual methods such as registering to take part in the Apprenticeship, displaying the information needed in the Apprenticeship activities, manipulating the data used to be used in Internship activities.
RANCANG BANGUN SISTEM ABSENSI DAN NOTIFIKASI MENGGUNAKAN RFID DAN WHATSAPP BLAST DI SMKN 1 KOTA SERANG
Authors: Ruhiawati Irma Yunita , Romdoni Mochamad Yusuf
Published: March 2022

School is one of the places that plays an important role in educating a child, especially in matters relating to behavior, intellectual intelligence, emotional intelligence and spiritual intelligence. All of that will be built from an early age which is based in the school environment, therefore how important schools are for children. Vocational High School is a level with education equivalent to Senior High School whose education has a certain field with the aim of graduating ready to work. The attendance or attendance system is needed by schools to assess a student's achievement. However, there is a problem where some schools currently use conventional methods in giving presence to their students, including SMKN 1 Kota Serang. This problem can result in the duration of teaching and learning time being reduced and the resulting data information is inaccurate. With the presence of a computerized attendance system that will make this problem resolved, therefore the authors intend to design and create an attendance or attendance system that facilitates schools, especially in terms of student attendance or attendance. For this study, the authors used Radio Frequency Identification (RFID) as a medium for automatic student attendance combined with web-based applications using the PHP programming language and MySQL Database Management System for processing student attendance data. For the system development method, the author uses the Waterfall method so that it can facilitate the design of the attendance system or student attendance.
PENERAPAN INTERNET SEHAT SEBAGAI INTERNET SERVICE PROVIDER MENGGUNAKAN NETWORK MONITORING SYSTEM ZABBIX DAN SQUID PROXY
Authors: Dwiyatno Saleh , Rakhmat Edy , Sulistiyono Sulistiyono , Mahruzzaman M Rafi
Published: March 2022

Internet users continue to grow. However, there are still many who have not experienced the Internet. One of the contributing factors is the cost of the Internet which is not cheap. Most Internet users get Internet access by subscribing to their respective ISPs. In addition, today more and more crimes are committed via the Internet. This study aims to provide a solution to reduce the cost of subscribing to an ISP and provide healthy Internet access. At Ciruas Center Shops, all traders and buyers use the Internet. Even if it's just for entertainment or even for buying and selling. The system applied in this research is where Internet users can get Internet access only by subscribing to one ISP. That way the fees paid to the ISP can be paid by mutual cooperation. The result of this research is an Internet provider system in which there is Zabbix Network Monitoring System (NMS) software as a network traffic monitor and Squid Proxy as a barrier as well as security when connected to the Internet.
PERANCANGAN SISTEM INFORMASI RESEP PULANG FARMASI RAWAT INAP DENGAN METODE E-PRESSCRIBING PADA RS XYZ
Authors: Dedifuadi Tb , Surahmat Ahmad , Fatullah Rizki
Published: March 2022

The Hospitals are one of the industries engaged in health services where hospitals are always required to have good, efficient, and quality services. Pharmacy services are one of the activities in hospitals that support quality health services, including affordable clinical pharmacy services for all levels of society, in this case the patient queue at the registration section because registration is done manually. because the dose must be calculated first before being formulated, so the waiting time for the prescription to go home is long. There is duplication of prescriptions or there is drug interaction in one prescription, so we have to confirm with the doctor first, there is a vacancy in the drug stock at the Inpatient Pharmacy, so we have to borrow drugs from another department first, if the other pharmacies don't have the stock of the drug, we have to call the doctor first to change the drug with the same indication, if the doctor doesn't want to change we are forced to buy medicine from outside, in a previous study by Dian Rakasiwi (JKOMA; 2018) in his journal mentioning the design of an e-prescribing system (electronic prescribing) or prescription electronically by using the codeigniter framework in the manufacture of drug prescriptions so that the drug redemption time is more effective and efficient. So that with the Design of Information Systems Waiting Time for Inpatient Pharmacy Discharge Prescriptions with the E-Presscribing Method at XYZ Hospital using the Waterfall method to describe the system, UML (Unified Modeling System) and MySQL are used as Web-based information data storage databases with Codeigniter as a framework, so that Hospitals can improve pharmacy services in terms of minimizing waiting time for prescriptions.
RANCANG BANGUN SISTEM INFORMASI PEMBUATAN SURAT KETERANGAN KERJA (PAKLARING) BERBASIS WEB PADA PT MAHAKARYA PUTRA MANDIRI
Authors: Musyarrofah Ofah , Lestari Mega
Published: March 2022

Development of the information system for making a certificate of work (paklaring) at PT. MPM is motivated by the process of making SKK,  which still has many obstacles in the manufacturing process, especially in the disposition or signature of letters. Where the letter requires a signature from the leadership, but the absence of the leadership in the office often takes a relatively long time so that there are delays and delays in receiving the letter to employees who need it. This research to build an information system for making work certificates in order to facilitate the process of submitting in the disposition of letters or signatures of leaders, to be more effective and fast in the process of making SKK, The tools used are PHP and MySQL as the database. The development method used is the System Development Life Cycle (SDLC) or Waterfall. The result of this research is the application for making a work certificate.
PERANCANGAN SISTEM INFORMASI PEMBANGUNAN JALAN PERDESAAN DI KABUPATEN SERANG (Studi Kasus Pada Desa Sukadalem Kecamatan Waringinkurung)
Authors: Widyawati Widyawati , Ratnasari Dedeh , Gunawan Indra
Published: March 2022

The PUPR Service of Serang Regency is located on Jalan Sama’un Bakri, Lopang, Serang2City, where there are many areas of duty, one part of which is the development section of the development section, which has tasks in road construction. In recording or data collection, road construction still uses Microsoft Excel, so it is not effective because of data loss and data duplication. So we need a new system that can support these activities. With the website-based information system using the PHP programming language, the database used is MySQL and the Waterfall method makes this information system usable anytime and anywhere. The purpose of this study is to design a rural road development information system that can provide information to the government regarding road construction and can monitor the progress of road construction in progress. The community can also see this information without having to come to the PUPR Office of Serang Regency to ask about information on the construction of their village roads that will be built and can report complaints related to road conditions, especially in the Serang district area in the community complaint feature so that it can be immediately followed up by government.
Organics and Nitrogen Removal from Wastewater Across a Plate of entrapped Mixed Microbial Cells
Authors:   National Taiwan University, Liu Chug-Chun , Ng Kok-Kwang , Wu Chien-Ju , Lin Cheng-Fang , Hong Pui-Kwan Andy , Yang Ping-Yi
Published: March 2022

This work investigated the concurrent removal of organics and nitrogen from wastewater as it passed through a slab of immobilized activated sludge of different thickness. Removals of chemical oxygen demand (COD) by 90% from feed of 300 mg L-1 and of ammonia nitrogen (NH3-N) by 30 to 50% from feed of 27 mg L-1 in the synthetic wastewater were achieved. Wastewater exited the entrapped mixed microbial cells (EMMC) bed of 0.01 m in depth after a hydraulic retention time of 8 h through the bed. Increasing the thickness by up to 5 folds resulted in no enhancement, indicating aerobic processes ceased within the bed depth. The removal of COD was by aerobic respiration and the removal of nitrogen by oxidation via nitrification, both occurring in the aerobic zone of the EMMC bed near the entrance surface. Denitrification occurred deeper into the anaerobic zone of the bed that removed nitrate, leaving behind <0.75 mg L-1 of nitrate in the emerging effluent. Apparent first-order rate constants were >0.29 h-1 and >0.045 h-1 for COD and NH3-N removal, respectively.
Crisis Probability Curves (CPCs): A Model for Assessing Vulnerability Thresholds Across Space and Over Time
Authors:   Potsdam Institute for Climate Impact Research, Acosta Lilibeth , Galli Fausto
Published: March 2022

The paper discusses the concept, methods and application of the Crisis Probability Curves (CPCs) to assess vulnerability to droughts in selected regions in India, Portugal, and Russia using published data on susceptibility and water stress indices. The CPCs, which are estimated from regression models and represented in a diagram as contour plots, are a spatiotemporal vulnerability yardstick that estimates vulnerability levels and thresholds to the combined impacts of environmental stress and human susceptibility (or lack of adaptive capacity). As compared to the CPCs for Russia, those for India and Portugal tilt more towards the water stress axis. This implies that the level of vulnerability in the latter countries tends to be more sensitive to the changes in water stress level than socio-economic susceptibility. For a particular water stress level, however, the probability of crisis occurring in India is higher than in Portugal. India has thus the lowest vulnerability threshold. Using pooled and panel regression, the information for three case study regions was combined to develop a common measure of vulnerability thresholds. Building common or generic thresholds will allow comparison of vulnerability across regions, which can be useful for policy in terms of developing priority list for providing adaptation support in vulnerable regions. However, the results revealed that there is a risk of under- or overestimating vulnerability thresholds when comparing regions not only with different level, but also varying sources of vulnerability. Thus, more crucial than developing generic vulnerability thresholds is highlighting differential vulnerability through selection of appropriate susceptibility indicators.
Energy Savings and Carbon Emission Reduction of Smart Lighting Installation in a Multipurpose and Residential Building in Santiago de Compostela, Spain
Authors:   University of Santiago de Compostela, Blanco Silva Fernando Blanco , Pereiro López Gabriel , Fernández Fontaiña Eduardo , López Díaz Alfonso
Published: March 2022

The excessive emissions of greenhouse gases into the atmosphere has increased the global average temperature resulting to a phenomenon known as global warming. One of the major greenhouse gasses is CO2 and the various efforts are focused on curbing its emissions. Using the case of a multipurpose and residential building at the University of Santiago de Compostela in Northwestern Spain, this study assessed the environmental impact of installing smart lighting. This study quantifies the CO2 emission reduction, and economic cost associated to the technical improvement. Such action resulted to saving 126 MWh and a reduction of carbon emissions of 25 T annually, with a return period of six years.
Particulate and Dissolved Forms of N, P and Organic C Transported From Major Land Uses in the Pagsanjan-Lumban Catchment to Laguna de Bay, Philippines
Authors:   University of the Philippines Los Baños, Sanchez Pearl , Oliver Danielle , Kookana Rai
Published: March 2022

The distribution of the particulate and dissolved forms of N, P and Organic C transported from major land uses in an agricultural watershed was determined. Total Kjeldahl N (TKN), total P (TP) and total organic C (TOC) were determined in both unfiltered (total) and filtered (< 1.2 μm) samples. The particulate fraction (> 1.2 μm, a conservative estimate) tended to dominate offsite transport of TKN, TP and TOC from agricultural land uses, especially in regions with more intense cropping systems, namely Pagsanjan and Lucban. The average proportions of particulate forms of N and P (PN and PP) were higher at Pagsanjan which is a rice growing area (73% of TKN and 68% of TP) than at Lucban (59% of TKN and 64 % of TP), which is generally under vegetable production. At Cavinti (a site under coconut production), particulate forms of TKN and TP were dominant while the soluble fraction dominated TOC transport. For the piggery site at Majayjay, particulate forms controlled the movement of TKN and TOC while the soluble form dominated TP transport. A significant, positive relationship was observed between total suspended solids (TSS) and PN and between TSS and POC at all sites. A significant relationship between TSS and TP was only noted at Lucban. Overall, the study showed that despite the conservative estimate (> 1.2 μm colloids only), particulate forms for C, N and P were the dominant fraction from all land uses in these agricultural catchments, except P from the piggeries site. The study suggests that the strategies to minimize or trap the particulate form may help reduce off-site migration of nutrients in the major catchment draining into Laguna de Bay, Philippines.
INVESTIGATION OF CHARACTERISTICS OF QUADRATIVE - AMPLITUDE MODULATION AFFECTING INTERFERENCE-RESISTANT RECEPTION
Authors:   Head of the department: Candidate of Technical Sciences, Associate Professor of the Department of radio Engineering devices and systems of Tashkent State Technical University, YARMUKHAMEDOV A.A.
Published: March 2022

The article analyzes the main reasons for reducing reliability, channel violations during the transmission and reception of digital television signals. The main regularities of noise-resistant formation of quadrature-amplitude modulation are investigated. Mathematical models, vector diagrams of the QAM signal and the results of a theoretical study of the dependence of the bit error probability on Eb/N0, to ensure noise-immune reception of digital television signals.
Scientific cooperation of Imam Bukhari and Imam Termezi
Authors:   Imam Termezi International Research Center, Zhoniev Muzaffarkhon
Published: March 2022

The study of the invaluable scientific and spiritual heritage of the great scientists and thinkers who lived and worked in our country, the scientific interpretation of their works, their popularization and bringing them to our people are becoming topical issues. The scientific heritage of two great scholars of hadith, Imam Bukhari and Imam Termizi, who compiled and improved the hadith, the most important source in the Islamic world after the Koran, has not lost its relevance today. Although various studies have been carried out on “Al-Jami as-Sahih” al-Bukhari and “Sunan” of Imam Termizi, the study of the scientific relationship between two hadith scholars, teacher and student, allows a deeper study of their heritage. The article focuses on the scientific relationship between the two scholars of hadith, as well as the hadith transmitted from each other in their writings, and their characteristics
U službi fašizma - akterke ustaškog pokreta između karijere, politike i zločina
Authors: Bitunjac Martina
Published: March 2022

Ustaški pokret je težio za ideologizacijom „hrvatske žene“, koja se „oslobađa“ ideje ravnopravnosti i žrtvuje za dobrobit „narodne zajednice“ – jedino u patrijarhalnoj ulozi majke i odgojiteljice „arijske rase“. Ta propagirana slika žene u ratnim godinama nije mogla zaživjeti jer je mobilizacija radnica u različita zanimanja bila potrebna za opstanak Nezavisne Države Hrvatske. Pripadnice ustaškog pokreta, koje su od početka aktivno podupirale Pavelićevu organizaciju, vrlo rijetko su bile ograničene na ulogu majke. Kao „dužnostnice“ politički su sudjelovale u formiranju nove države, te su rukovodile „Ženskom ustaškom mladeži“ i „Ženskom lozom hrvatskog ustaškog pokreta“ gdje su bile između ostalog zadužene za širenje ustaške propagande i mobilizaciju djevojčica i žena u pokret. Niti podupiranje zločinačkog sistema nije bila samo domena muških pripadnika „ustaše“. Članak, koji je baziran na knjizi „Verwicklung. Beteiligung. Unrecht. Frauen und die Ustaša-Bewegung“ (Uključenost. Sudjelovanje. Nepravda. Žene i ustaški pokret) posvetit će se ideološkim mišljenjima i mogućnosti djelovanja žena aktivnih u fašističkom pokretu, od „prvoborkinja“ ustaškog pokreta do ženskog personala u koncentracijskom logoru Jasenovac.
Odnos prema pravoslavnim crkvama u Slavonskoj eparhiji u vrijeme socijalizma (1945.-1990.)
Authors: Škiljan Filip
Published: March 2022

Autor najvećim dijelom na temelju arhivskog gradiva iz Hrvatskog državnog arhiva iz fonda Komisija za odnose s vjerskim zajednicama NR/SR Hrvatske donosi podatke o zanemarivanju i neobnavljanju srpskih pravoslavnih crkava na području Slavonske eparhije (Donji Miholjac, Našice, Požega, Orahovica, Slatina, Virovitica, Pakrac, Slavonski Brod, Nova Gradiška, Novska, Đakovo) u vrijeme socijalizma. Na osnovu istraživanja autor zaključuje da su jedan dio crkava koje su teško oštećene u Drugom svjetskom ratu od strane ustaša i Nijemaca, komunističke vlasti i sami mještani nisu obnavljali nakon Drugog svjetskog rata. U poslijeratnom razdoblju bilo je također i mnogo slučajeva da su lokalne vlasti otežavale obnovu pojedinih objekata usprkos činjenici što je Slavonska eparhija uspijevala namaknuti sredstva za njihovu obnovu. Autor se u radu također bavi i odnosom lokalnih vlasti prema pravoslavnim svećenicima na području Slavonske eparhije.
Češi v „Domovinské válce“ – Slavonie 1991 – 1995
Authors: Zona Pavel
Published: March 2022

Professional article „Czechs in Domovinska war – Slavonia 1991–1995“ was
created as a logical product of the work of the author, which deals with the Czech and Slovak minority in the former Yugoslavia and builds on his previous work looking into the involvement of Czechs and Slovaks to the fight of liberation of the peoples of the former Yugoslavia in World War II. The main theme of the article is the impact of the so-called Domovinska war in Croatia in the years 1991–1995 to the Czech minority in Slavonia and the involvement of the inhabitants of the Czech
nationality in the combating in this war. When examining these issues, the author came from archival sources, primarily from materials stored in the archives of the Association of Czechs in the Republic of Croatia in Daruvar, from a few articles written on the subject, the study of contemporary newspapers and interviews and consultations with inhabitants of Daruvar and the surrounding area. The result of the work is not only presented in this article, but also in many other materials and incentives to continue working with regard to the entire Croatia, the Slovak minority and on the participation of Czech and Slovak soldiers in the mission UNPROFOR. From the perspective of the author, this is the „introductional“ work for extended research and publishing activities in the area, he chose.
Kratak osvrt na kolonizaciju Čeha na područje zapadne Slavonije i sjeverozapadne Hrvatske
Authors: Herout Vjenceslav
Published: March 2022

Kolonizacija Čeha na hrvatska područja spominje se u više radova, posebno ona koja se odvijala tijekom 19. stoljeća. Njome su se najprije bavili uglavnom istraživači iz Češke, dok su se domaći istraživači time počeli baviti tek od druge polovine 20. stoljeća. U novijim radovima nailazimo uglavnom na već prikupljene podatke iz ranije objavljenih radova, malo je onih koji su produbili ranije spoznaje iz nekih drugih izvora. Ipak ono što su oni objavili, proširilo je vidike ovdašnjeg čitateljstva o pitanju kolonizacije Čeha. O njoj i doprinosu Čeha na hrvatsko gospodarstvo i neke segmente kulture, moguće je čitati u mnogim zapisima. Ipak je do danas još mnogo toga ostalo bez odgovora. Do sada nije objavljena nijedna sinteza, objedinjen prikaz, u kojem bi se našli precizni podatci odakle su došle pojedine obitelji pa se u zadnje vrijeme javljaju i neprovjereni i netočni zapisi. Češki istraživači iz razdoblja Austro-Ugarske nisu se previše bavili tim pitanjem, osim uopćenih podataka do kojih su došli u kontaktu s doseljenim češkim obiteljima. I njima je bio problem spoznaja da mnogi potomci doseljenih obitelji više nisu znali odakle su došli njihovi predci, pogotovo ukoliko su došli u prvoj polovini 19. stoljeća, a pisanih dokaza o tome nisu sačuvali. Jednako tako navodi uzroka seoba su različiti, ponekad nepotpuni, a one zapisane prikupili su češki istraživači obilazeći ovdašnje doseljenike ne provjeravajući ih u sredinama iz kojih su se doselili. Ni ovaj uradak neće dati odgovore na sva ta pitanja, ali će biti dobar putokaz svima onima koji će se htjeti baviti tim pitanjem, ali za još manji prostor nego je u ovom naslovu. Očekuje se više i od brojnih mladih istraživača iz Češke koji odgovore na takva pitanja još i danas istražuju u Hrvatskoj, ali ponekad zaobilaze neke svoje arhive koji kriju još nepoznatu građu koja se odnosi i na pitanje kolonizacije Čeha na hrvatske prostore.
Pengaruh Kompensasi, Motivasi dan Lingkungan Kerja terhadap Kepuasan Kerja Karyawan:
Authors: Lindasari Kuyun , Herawati Jajuk , Septyarini   Epsilandri
Published: March 2022

This study aims to determine the effect of the independent variables, namely compensation, motivation, and work environment on the dependent variable, namely job satisfaction. This type of research is quantitative research. The population is all employees in Balai Diklat Industri Yogyakarta. The sample is 53 samples. The sampling technique used nonprobability technique (saturated sampling). The data collection method in this study is a questionnaire distributed to all employees Balai Diklat Industri Yogyakarta. The data analysis technique used multiple linear regression, t test (partial), f test (simultaneous), and coefficient of determination (R2). The results of this study indicate that compensation has no positive and significant effect on employee job satisfaction, motivation has a positive and insignificant effect on employee job satisfaction, work environment has a positive and significant effect on employee job satisfaction, and compensation, motivation and work environment have a simultaneous effect on job satisfaction. employee work.

Keywords: Compensation, Motivation, Work Environment, Job Satisfaction
Pengaruh Brand Ambassador BTS (Bangtan Boys) dan E-Trust terhadap Minat Beli
Authors: Ayu Laras Tri
Published: March 2022

The large amount of e-commerce users in Indonesia has made Marketplace as one of the biggest players in the most popular e-commerce business nowadays. This opportunity used by big companies to compete to attract people's purchase interest in Indonesia. In order to growing purchase interest on marketplace requires a high sense of trust and strong promotion using brand ambassadors to disseminate information and attract consumers to create a sense of trust for making purchases. The purpose of this study is to determine how much the relationship and affect of BTS as brand ambassadors and e-trust on puchase interest. The object of this research is the community of Tokopedia Marketplace users on social media. The data collection technique used is the Questionnaire, Observation and Literature technique. The results show that there is a correlation between brand ambassadors and e-trust for 0.677, there is a partial effect of brand ambassadors on purchase interest for 0.142, there is a partial effect of e-trust on purchase interest for 0.528, there is a simultaneous affect of brand ambassadors and e-trust on purchase interest for 0.670.
Komunitas Pengusaha Muslim : Pengaruh Motivasi Berwirausaha, Dukungan Finansial dan Peluang Pasar terhadap Niat Berwirausaha
Authors: 'Azmi Harridhi Mukminin , Herianingrum Sri , Junaedi Dedi , Arsyad Muhammad Rizal , Salistia Faisal
Published: March 2022

Penelitian ini bertujuan untuk menganalisis pengaruh motivasi kewirausahaan, dukungan finansial dan ketersediaan pasar terhadap niat berwirausaha. Penelitian ini penting dilakukan karena jumlah pengusaha di Indonesia jauh lebih sedikit dibandingkan dengan negara tetangga, seperti Singapura 7 persen, Malaysia 6 persen dan Thailand 5 persen serta mengetahui hubungan motivasi kewirausahaan, dukungan finansial dan ketersediaan pasar terhadap sikap kewirausahaan pengusaha-pengusaha muslim yang tergabung dalam komunitas Forum Bisnis Gontor.

Metode penelitian menggunakan pendekatan kuantitatif dengan data sekunder dan primer. Data sekunder diperoleh dari dari literatur berupa buku dan jurnal yang berkaitan dengan penelitian, sedangkan data primer diperoleh dari dengan menyebarkan kuesioner secara online. Teknik pengumpulan data menggunakan purposive sampling, sedangkan teknik analisa data menggunakan Structural Equation Modeling-Partial Least Square (SEM-PLS). Adapun variabel yang digunakan dalam penelitian ini yaitu motivasi kewirausahaan, dukungan finansial dan ketersediaan pasar, sikap berwirausaha dan niat berwirausaha.

Hasil penelitian menunjukkan bahwa motivasi berwirausaha berpengaruh positif terhadap sikap berwirausaha, motivasi berwirausaha tidak berpengaruh terhadap niat berwirausaha, dukungan finansial tidak berpengaruh terhadap sikap berwirausaha, sikap berwirausaha berpengaruh positif terhadap niat berwirausaha, peluang pasar tidak berpengaruh terhadap sikap berwirausaha dan peluang pasar tidak berpengaruh terhadap niat berwirausaha. Temuan penelitian ini memberikan bukti bahwa motivasi berwirausaha memberikan dampak terhadap sikap para pengusaha muslim dalam berwirausaha.
Niat Berperilaku Masyarakat dalam Menggunakan Vaksin halal : Penerapan Teori of Planned Behaviour
Authors: Azizah Haifah Nabilatul , Purwanto Purwanto , Alfianto Achmad Nur , Labib Achmad
Published: March 2022

Vaccines have an important influence in overcoming the covid-19 virus outbreak, the higher public doubts about the covid-19 vaccine can affect people's intentions to use the covid-19 vaccine. The purpose of this study is to find out how the Theory Planned of Behavior is applied in predicting people's behaviour to use the covid-19 vaccine with subjective norms focused on the media. This study collects data through an online survey by distributing questionnaires from Google Form. The sample was taken as many as 154 people of Magelang district aged 16-40 years had been selected based on purposive sampling technique. Data analysis using SEM-PLS. The results of this study show that of the three variables, namely attitudes, subjective norms and perceived behavior control, only the attitude variable has a significant influence on the intention to use the covid-19 vaccine.
Faktor-Faktor Yang Mempengaruhi Struktur Modal Pada Perusahaan Jasa Subsektor Kontruksi Bangunan Di Bei Tahun 2016-2020
Authors: Murti Oktavia Tri Kusuma , Suhendro Suhendro , Wijayanti Anita
Published: March 2022

Penelitian ini bertujuan untuk menganalisis faktor yang mempengaruhi struktur modal pada perusahaan jasa subsektor kontruksi bangunan di Bursa Efek Indonesia (BEI) periode 2016-2020. Jenis penelitian ini adalah kuantitatif. Penelitian ini menggunakan purposive sampling dalam penentuan sampel sehingga dihasilkan 7 perusahaan yang memenuhi kriteria sampel. Metode yang digunakan dalam penelitian ini adalah regresi linier berganda. Hasil penelitian ini menunjukan bahwa variable struktur aktiva dan likuiditas berpengaruh terhadap struktur modal perusahaan jasa subsektor kontruksi bangunan. Profitabilitas dan ukuran perusahaan tidak berpengaruh terhadap struktur modal perusahaan jasa subsektor kontruksi bangunan.
Gender features of awareness and attitudes of adolescents to a healthy lifestyle
Authors: Filkina Olga M. , Kocherova Olga Yu. , Malyshkina Anna I. , Vorobyeva Elena A. , Dolotova Natalya V.
Published: March 2022

Introduction. For the formation of the health of children and adolescents, it is essential to study their awareness of the risk factors for health disorders and the formation of stereotypes of a healthy lifestyle. Materials and methods. According to the questionnaire developed by us, “Awareness of adolescents about a healthy lifestyle”, a survey included 245 15-17 year adolescents (133 girls, 112 boys) attending secondary schools in Ivanovo. Results. In self-assessment of awareness, regardless of gender, adolescents highly value their knowledge of a healthy lifestyle. Adolescents often want to learn more about proper nutrition, health risk factors, reproductive health issues. Boys more often than girls consider it unnecessary to adhere to the rules of personal safety, safe reproductive behaviour, full compliance with medical recommendations, admit the possibility of self-medication, go to doctors only in case of illness, violate the principles of a healthy diet and daily routine. It is more difficult for boys than girls to maintain good personal hygiene. Of the negative school factors, girls more often than boys note high pedagogical loads difficulties in relationships with classmates and teachers. They often believe that they need to spend less time at the computer, observe the daily routine, spend enough time to sleep and rest in the fresh air, eat right. That is, they are more responsible and self-critical. Girls more often emphasize their independence in matters of a healthy lifestyle. They believe that for this, they need their conviction and time. Limitations. The study has age (15-17 year teenagers), regional (Ivanovo) and educational (students of secondary educational institutions) restrictions. Conclusion. The revealed gender characteristics of awareness and attitude of adolescents to healthy lifestyle make it necessary to take them into account when drawing up programs to improve adolescents’ knowledge. More attention should be paid to safety issues for boys, and for girls, psychological issues should be included.