bluuebunny/crossref_metadata_2025 huggingface dataset:
Friction generated by elastomeric ligature with and without polymer coating
Authors: Martins Mariana , Lima Tatiana Araújo , Teixeira Andressa , Artese Flavia , MENDES Alvaro
Published: April 2017

O objetivo deste estudo foi comparar, in vitro, o atrito gerado por ligaduras elásticas com cobertura polimérica com ligaduras convencionais. Foram testados três calibres de fio: 0.020", 0.019" x 0.025" and 0.019" x 0.026 ". Foram confeccionadas duas placas de acrílico, onde emu ma placa foi colado um bráquete de incisivo central superior e na outra placa foi feito uma canaleta onde os fios ortodônticos eram fixados. As placas de acrílico foram fixadas e reguladas em uma máquina de ensaio de tração de maneira que o fio fosse fixado ao bráquete sem nenhuma angulação. Para cada fio foram testadas 10 ligaduras de cada tipo. Os fios foram tracionados pelo slot do bráquete a uma distância de 5mm com uma velocidade constante de 5mm/min. Os resultados obtidos foram comparados pelo teste t de Student com significância de p<0.05, e revelaram a existência de diferenças significativas entre as forces geradas para cada caliber de fio. As ligaduras convencionais sem cobertura polimérica geraram forças significantemente maiores que as ligaduras com cobertura polimérica. As ligaduras com cobertura polimérica geraram menor atrito que as ligaduras convencionais em todos os calibres de fio avaliados, sugerindo que este tipo de ligaduras pode ser usado como escolha nas mecânicas de distalização.
Destination promotion and marketing with social media: Case of Home Turkey
Destinasyon tanıtımı ve pazarlamasında sosyal medya: Home Turkey örneği
Authors: Çelik Pınar , Yüzbaşıoğlu Nedim , Topsakal Yunus
Published: April 2017

One of the changes in the tourism and services sector since the early 1980s is the globalization of tourism. The globalization of the tourism sector has revealed the importance of destinations. The countries that want to increase their share of tourism revenues have begun to pay more attention to the destinations. This lead the destination competitiveness between countries. The countries have started to promote destinations via their official social media accounts to ensure competitive advantage and maintain the existing competitive advantages. The purpose of this study is to review the content of photos shared from Turkey's official social media account, Home Turkey. For this purpose 1300 photographs were reviewed. Photos are grouped under 7 themes in terms of content. They are food and beverage, blue voyage, natural attractions, hidden gems, iconic experiences, blue flag, UNESCO, Anatolian heritage and adventure tourism. While it has been determined the most shared photo are related to iconic experiences, the most shared photo about food and beverage is tea, baklava and karnıyarık. In general, most of the shares have been made on tulips and hand-woven carpets. Tulips are prominent because it is one of the symbols of Istanbul city because the sharing about tulip was made by referring to the Istanbul city. ÖzetTurizm ve hizmet sektöründe 1980’lerin ilk yıllarından beri oluşan en çarpıcı değişimlerden biri turizmin küreselleşmesidir. Turizm sektörünün küreselleşmesi beraberinde destinasyonların önemini ortaya çıkarmıştır. Turizm gelirlerinden aldığı payı arttırmak isteyen ülkeler destinasyonlarına daha çok önem vermeye başlamışlardır. Bu gelişme beraberinde destinasyon rekabetçiliğini getirmiştir. Rekabet avantajı sağlamak ve mevcut rekabet avantajlarını korumak için ülkeler artık resmi sosyal medya hesaplarından tanıtıma başlamıştır. Bu çalışmanın amacı Türkiye’nin resmi sosyal medya hesabı olan Home Turkey hesabından paylaşılan fotoğrafların içeriğini incelemektir. Bu amaçla 1300 fotoğraf incelenmiştir. Fotoğraflar içerik bakımından 7 tema altında toplanmıştır. Bunlar; yiyecek-içecek, mavi yolculuk, doğal çekicilikler, gizli cennetler, ikonik deneyimler, mavi bayrak, UNESCO, Anadolu mirası ve macera turizmidir. En çok paylaşımın ikonik deneyimler ile ilgili olduğu belirlenmişken, yiyecek-içecek ile ilgili en çok paylaşılan fotoğraf çay, baklava ve karnıyarıktır. Genel olarak ise en çok lale ve el dokuması halı ile ilgili paylaşımlarda bulunulmuştur. Lale İstanbul şehriyle özdeşleştiği için öne çıkmıştır, çünkü lale ilgili paylaşımlar İstanbul şehrine atıf yapılarak yapılmıştır.
𝒟1,2(ℝ
N
) versus C(ℝ
N
) local minimizer on manifolds and multiple solutions for zero-mass equations in ℝ
N
Authors: Carl Siegfried , Costa David G. , Tehrani Hossein
Published: April 2017

We consider functionals of the form

J
⁢

(
u
)

=

1
2

⁢

∫

ℝ
N

|

∇
⁡
u

|

2

-

∫

ℝ
N

b
⁢

(
x
)

⁢
G
⁢

(
u
)

J(u)=\frac{1}{2}\int_{{\mathbb{R}}^{N}}|\nabla u|^{2}-\int_{{\mathbb{R}}^{N}}b%
(x)G(u)

on a

C
1

{C^{1}}

-submanifold M of

𝒟

1
,
2

⁢

(

ℝ
N

)

{\mathcal{D}^{1,2}({\mathbb{R}}^{N})}

,

N
≥
3

{N\geq 3}

, where G is the primitive of some “zero-mass” nonlinearity g (i.e.,

g
′

⁢

(
0
)

=
0

{g^{\prime}(0)=0}

), and the weight function

b
:

ℝ
N

→
ℝ

{b:{\mathbb{R}}^{N}\to{\mathbb{R}}}

is merely supposed to belong to

L
1

⁢

(

ℝ
N

)

∩

L

2
*

2
*

-
p

⁢

(

ℝ
N

)

{L^{1}({\mathbb{R}}^{N})\cap L^{\frac{2^{*}}{2^{*}-p}}({\mathbb{R}}^{N})}

for some

2
<
p
<

2
*

{2<p<2^{*}}

, and to possess a certain decay behavior. Let V be the subspace of

𝒟

1
,
2

⁢

(

ℝ
N

)

{\mathcal{D}^{1,2}({\mathbb{R}}^{N})}

given by

V
:=

{

v
∈

𝒟

1
,
2

⁢

(

ℝ
N

)

:

v
∈

C
⁢

(

ℝ
N

)

⁢
 with 
⁢

sup

x
∈

ℝ
N

⁡

(

1
+

|
x
|

N
-
2

)

⁢

|

v
⁢

(
x
)

|

<
∞

}

{V:=\{v\in\mathcal{D}^{1,2}({\mathbb{R}}^{N}):v\in C({\mathbb{R}}^{N})\mbox{ %
with }\sup_{x\in{\mathbb{R}}^{N}}(1+|x|^{N-2})|v(x)|<\infty\}}

. We prove that a local minimizer of the constrained functional

J
|

M

{J|_{M}}

with respect to the V-topology must be a local minimizer with respect to the “bigger”

𝒟

1
,
2

⁢

(

ℝ
N

)

{\mathcal{D}^{1,2}({\mathbb{R}}^{N})}

-topology. This result allows us to prove the existence of multiple nontrivial solutions of the zero-mass equation

-

Δ
⁢
u

=

b
⁢

(
x
)

⁢
g
⁢

(
u
)

{-\Delta u=b(x)g(u)}

in

ℝ
N

{{\mathbb{R}}^{N}}

, where

g
:

R
→
ℝ

{g:R\to{\mathbb{R}}}

is a subcritical nonlinearity, which is superlinear at zero and at

∞

{\infty}

.
Fourier–Mukai and autoduality for compactified Jacobians. I
Authors: Melo Margarida , Rapagnetta Antonio , Viviani Filippo
Published: April 2017

To every singular reduced projective curve X one can associate, following Esteves, many fine compactified Jacobians, depending on the choice of a polarization on X, each of which yields a modular compactification of a disjoint union of the generalized Jacobian of X. We prove that, for a reduced curve with locally planar singularities, the integral (or Fourier–Mukai) transform with kernel the Poincaré sheaf from the derived category of the generalized Jacobian of X to the derived category of any fine compactified Jacobian of X is fully faithful, generalizing a previous result of Arinkin in the case of integral curves. As a consequence, we prove that there is a canonical isomorphism (called autoduality) between the generalized Jacobian of X and the connected component of the identity of the Picard scheme of any fine compactified Jacobian of X and that algebraic equivalence and numerical equivalence of line bundles coincide on any fine compactified Jacobian, generalizing previous results of Arinkin, Esteves, Gagné, Kleiman, Rocha, and Sawon.

The paper contains an Appendix in which we explain how our work can be interpreted in view of the Langlands duality for the Higgs bundles as proposed by Donagi–Pantev.
Synergistic effects of retinoic acid and graphene oxide on the physicochemical and in-vitro properties of electrospun polyurethane scaffolds for bone tissue engineering
Authors: Safikhani Mohammad Mahdi , Zamanian Ali , Ghorbani Farnaz
Published: April 2017

Tissue engineering scaffolds simulate extracellular matrixes (ECMs) to promote healing processes of damaged tissues. In this investigation, ECM were simulated by retinoic acid-loaded polyurethane-graphene oxide nanofibers to regenerate bone defects. Scanning electron microscopy (SEM) micrographs, Fourier transform infrared (FTIR) spectrum and X-ray diffraction (XRD) patterns proved the synthesis of graphene oxide (GO) nanosheets. SEM micrographs of nanofibers demonstrated through the formation of homogeneous and bead free fibrous scaffolds that the diameter of fibers were reduced by decreasing the applied voltage in an electrospinning process and the addition of GO. According to the results, the addition of GO to the polyurethane (PU) solution led to an increase in mechanical strength which is the most important parameter in the hard tissue repair. The GO-containing scaffolds showed an increased wettability, swelling, biodegradation and drug release level. Release behavior in nanocomposite scaffolds followed the swelling and biodegradation mechanisms, so osteogenic expression was possible by incorporating retinoic acid (RA) in PU-GO nanofibrous scaffolds. Biological evaluations demonstrated that composite scaffolds are biocompatible and support cellular attachment in which RA-loaded samples represented better cellular spreading. In brief, nanocomposite fibers showed desired that the physicochemical, mechanical and biological properties and synergic effects of GO and RA in osteogenic activity of MG-63 cells produced favorable constructs for hard tissue engineering applications.
On the large-scale geometry of diffeomorphism groups of 1-manifolds
Authors: Cohen Michael P.
Published: April 2017

We apply the framework of Rosendal to study the large-scale geometry of the topological groups

Diff
+
k

⁡

(

M
1

)

{\operatorname{Diff}_{+}^{k}(M^{1})}

, consisting of orientation-preserving

C
k

{C^{k}}

-diffeomorphisms (for

1
≤
k
≤
∞

{1\leq k\leq\infty}

) of a compact 1-manifold

M
1

{M^{1}}

(

=
I

{=I}

or

𝕊
1

{\mathbb{S}^{1}}

). We characterize the relative property (OB) in such groups:

A
⊆

Diff
+
k

⁡

(

M
1

)

{A\subseteq\operatorname{Diff}_{+}^{k}(M^{1})}

has property (OB) relative to

Diff
+
k

⁡

(

M
1

)

{\operatorname{Diff}_{+}^{k}(M^{1})}

if and only if

sup

f
∈
A

sup

x
∈

M
1

|
log

f
′

(
x
)

|
<
∞

{\sup_{f\in A}\sup_{x\in M^{1}}\lvert\log f^{\prime}(x)|<\infty}

and

sup

f
∈
A

⁡

sup

x
∈

M
1

⁡

|

f

(
j
)

⁢

(
x
)

|

<
∞

{\sup_{f\in A}\sup_{x\in M^{1}}|f^{(j)}(x)|<\infty}

for every integer j with

2
≤
j
≤
k

{2\leq j\leq k}

. We deduce that

Diff
+
k

⁡

(

M
1

)

{\operatorname{Diff}_{+}^{k}(M^{1})}

has the local property (OB), and consequently a well-defined non-trivial quasi-isometry class, if and only if

k
<
∞

{k<\infty}

. We show that the groups

Diff
+
1

⁡

(
I
)

{\operatorname{Diff}_{+}^{1}(I)}

and

Diff
+
1

⁡

(

𝕊
1

)

{\operatorname{Diff}_{+}^{1}(\mathbb{S}^{1})}

are quasi-isometric to the infinite-dimensional Banach space

C
⁢

[
0
,
1
]

{C[0,1]}

.
On orders of elements of finite almost simple groups with linear or unitary socle
Authors: Grechkoseeva Mariya A.
Published: April 2017

We say that a finite almost simple G with socle S is admissible (with respect to the spectrum) if G and S have the same sets of orders of elements.
Let L be a finite simple linear or unitary group of dimension at least three over a field of odd characteristic.
We describe admissible almost simple groups with socle L. Also we calculate the orders of elements of the coset

L
⁢
τ

{L\tau}

, where τ is the inverse-transpose automorphism of L.
On the surjectivity of the power maps of a class of solvable groups
Authors: Dani S. G. , Mandal Arunava
Published: April 2017

Let G be a group containing a nilpotent normal subgroup N with central series

{

N
j

}

{\{N_{j}\}}

such that each

N
j

/

N

j
+
1

{N_{j}/N_{j+1}}

is an

𝔽

{\mathbb{F}}

-vector space over a field

𝔽

{\mathbb{F}}

and the action of G on

N
j

/

N

j
+
1

{N_{j}/N_{j+1}}

induced by the conjugation action is

𝔽

{\mathbb{F}}

-linear. For

k
∈
ℕ

{k\in\mathbb{N}}

we
describe a necessary and sufficient condition for all elements from any coset xN,

x
∈
G

{x\in G}

, to admit kth roots in G,
in terms of the action of x on the quotients

N
j

/

N

j
+
1

{N_{j}/N_{j+1}}

. This yields in particular a condition for surjectivity
of the power maps, generalising various results known in special cases. For

𝔽

{\mathbb{F}}

-algebraic groups we also characterise
the property in terms of centralisers of elements. For a class of Lie groups, it is shown that surjectivity of the kth power map,

k
∈
ℕ

{k\in\mathbb{N}}

, implies the same for the restriction of the map to the solvable radical of the group. The results are applied
in particular to the study of exponentiality of Lie groups.
Primary pigmented nodular adrenocortical disease: literature review and case report of a 6-year-old boy
Authors: Katanić Dragan , Kafka Dejan , Živojinov Mirjana , Vlaški Jovan , Budakov Zorana , Knežević Pogančev Marija , Vorgučin Ivana , Ćuk Tomislav
Published: April 2017

Cushing’s syndrome is rare in childhood and is usually caused by a pituitary adenoma. Primary hyperfunction of adrenal glands is less frequent, particularly primary pigmented nodular adrenocortical disease (PPNAD). It occurs usually in children and adolescents, with female preponderance, while Cushing’s disease has increased frequency in prepubertal males. A case of a 6-year-old boy is presented with isolated non-familiar PPNAD. The clinical pattern involved Cushingoid appearance, hypertension, virilization and depressive mood. Laboratory analyses showed loss of circadian rhythm of cortisol, undetectable adrenocorticotropic hormone (ACTH) level, impaired fasting glucose, polycythemia and elevated white blood count (WBC). Radiology investigation revealed a slightly enlarged medial branch of the left adrenal gland and a normal right one, so a unilateral adrenalectomy was performed. Pathohistology described multiple dark brownish pigmented nodules of various sizes confined to the cortex. Contralateral adrenalectomy was done 3 months later. Follow-up of 3 years was uneventful, except for one adrenal crisis during an intercurrent respiratory illness.
Crystal structure of (μ2-[2,2′-bis(diphenylphosphino)-1,1′-binaphthalene oxide-κ2
O,P])-iodido copper(I), C44H32CuIOP2
Authors: Wang Ying-Feng , Li Si-Fan , Lin Sen , Cui Yang-Zhe , Jin Qiong-Hua
Published: April 2017

C44H32CuIOP2, monoclinic, P21/c (no. 14), a = 17.1995(14) Å, b = 11.4175(9) Å, c = 19.1704(17) Å, β = 104.263(2)°, V = 3648.5(5) Å3, Z = 4, R
gt(F) = 0.0464, wR
ref(F
2) = 0.1387, T = 298(2) K.
On Steady-State Multiple Resonances for a Modified Bretherton Equation
Authors: Sun Jianglong , Cui Jifeng , He Zihan , Liu Zeng
Published: April 2017

In this article, a modified Bretherton equation is considered to further check if steady-state multiple resonances exist not only for water waves but also for other dispersive medium. The linear resonance condition analysis shows that different components may interact with each other so multiple resonances may happen. Convergent steady-state solutions are obtained by solution procedure based on the homotopy analysis method (HAM) and the collocation method. Amplitude spectrum analysis confirms that more components indeed join the resonance as the nonlinearity increases. This article suggests that steady-state multiple resonance may exist in other dispersive system.
No Evidence for Differential Relations of Hedonic Well-Being and Eudaimonic Well-Being to Gene Expression: A Comment on Statistical Problems in Fredrickson et al. ()
Authors: Nickerson Carol A.
Published: April 2017

In a study of the relation between well-being and gene expression, Fredrickson et al. (2013, Proceedings of the National Academy of Sciences of the USA, 110 (33), 13684–13689) concluded that hedonic well-being and eudaimonic well-being have similar affective correlates but different gene transcriptional correlates in human immune cells. This comment addresses four statistical problems in Fredrickson et al.’s (2013) analyses. First, an idiosyncratic two-factor scoring rather than the documented and well-validated three-factor scoring was used for the instrument assessing well-being. Second, the analyses relating hedonic well-being and eudaimonic well-being to affect did not include the same variables as the analyses relating these two well-being variables to gene expression, invalidating any comparison between them. Third, hedonic well-being and eudaimonic well-being were highly correlated, resulting in untheorized and unrecognized suppression effects that accounted for their supposed differential relations with gene expression. Fourth, the method of computing p values for the one-sample t tests discarded information and violated the assumption of independence for those tests. These problems cast considerable doubt on the validity of Fredrickson et al.’s (2013) conclusions.
Antimalarial Herbal Plants in Kupang, Indonesia
Authors: Ihwan Ihwan , Koda Sari Hauliah Ahmad
Published: April 2017

Malaria is an infectious disease caused by Plasmodium parasite transmitted through female Anopheles mosquito bite. This disease is harmful because Plasmodium is known to be resistant to antimalarial drugs. The emergence of malaria resistance has raised concerns among researchers to look for any alternative antimalarial drugs. There are some plants potentially used as antimalarial drugs that should bewell-documented through scientific research. This study aimed to get to know plant species that has antimalarial activity in Kupang region. Method: This research applied qualitative descriptive method while using exploration method specifically in the sampling process. Every sample is then taken for preservation as herbarium and identified based on its morphological features using determination key handbook. The result showed that there are 17 species of antimalarial plant in 10 observational sites. Those species of antimalarial plants i.e. Tithonia diversifolia, Momordica charantia, Cyperus rotundus, Strychnos lingustrina, Andrographis paniculata, Callicarpa longifolia, Tinospora crispa, Piper betle, Plectranthus scutellarioides, Alstonia scholaris, Carica papaya, Amaranthus spinosus, Artocarpus champeden, Cassia siamea, Azadirachta indica, Helianthus annuus and Blumea balsamifera. Therefore, the availability of the plant species with antimalarial activity in Kupang needs to be explored and developed as an alternative approach for the society in treating Malarial diseases.
Constructivist Learning Environment During Virtual and Real Laboratory Activities
Authors: Widodo Ari , Maria Resik Ajeng , Fitriani Any
Published: April 2017

Laboratory activities and constructivism are two notions that have been playing significant roles in science education. Despite common beliefs about the importance of laboratory activities, reviews reported inconsistent results about the effectiveness of laboratory activities. Since laboratory activities can be expensive and take more time, there is an effort to introduce virtual laboratory activities. This study aims at exploring the learning environment created by a virtual laboratory and a real laboratory. A quasi experimental study was conducted at two grade ten classes at a state high school in Bandung, Indonesia. Data were collected using a questionnaire called Constructivist Learning Environment Survey (CLES) before and after the laboratory activities. The results show that both types of laboratories can create constructivist learning environments. Each type of laboratory activity, however, may be stronger in improving certain aspects compared to the other. While a virtual laboratory is stronger in improving critical voice and personal relevance, real laboratory activities promote aspects of personal relevance, uncertainty and student negotiation. This study suggests that instead of setting one type of laboratory against the other, lessons and follow up studies should focus on how to combine both types of laboratories to support better learning.
Various Plants of Traditional Rituals: Ethnobotanical Research Among The Baduy Community
Authors: Iskandar Johan , Iskandar Budiawati S.
Published: April 2017

On the basis of recent studies in many places of developing countries it has been revealed that the practices of conservation of biodiversity has strongly determined by traditional ecological knowledge, and beliefs or cosmos. The aim of the study namely to elucidate; (1) some traditional rituals in the swidden management system of the Baduy community; (2) various plants that have been  used for performing some rituals in the swidden management system of the Baduy community; and (3) some functions of various plants that have been used in the rituals of the swidden management system of the Baduy community. A qualitative method with ethnobotanical approach was applied in this study. The result of study shows that 9 kinds of the traditional rituals that have been predominantly undertaken by the Baduy community in the management of swidden farming system. At least 50 plant species representing 28 families have been used for those performing traditional rituals. The main function of plants in the rituals is considered as the symbolic meaning and rational function. The result of study has been considered very important that the traditional ecological knowledge and beliefs must be considered to conserve biological diversity.   
Hairy Root Induction on Justicia gendarussa by Various Density of Agrobacterium rhizogenes strain LB 510
Authors: Wahyuni Dwi Kusuma , Hafida Siti Nur , Ermayanti Tri Muji , Wardoyo Bambang Prajoga Eko , Purnobasuki Hery , Utami Edy Setiti Wida
Published: April 2017

Gandarusa (Justicia gendarussa Burm.f.) is an Indonesian medicinal plant that has many benefits as drug and male contracetive. For industrial needs, Gandarusa must be  available in large quantity. Hairy root culture is one of methode to produce phytochemistry compound. The objective of the study was to examine the effect of various density of Agrobacterium rhizogenes strain LB510 on hairy roots induction of gandarusa (Justicia gendarussa Burm.f.) leaf plant. Leaf explants were inoculated in MS liquid medium with various density of OD600 = 0.1; 0.2; 0.3; 0.4; and 0.5. Explants were co-cultivated for 2 days on MS solid medium without any hormone then sub-cultured on MS solid medium containing antibiotic cefotaxim 300 ppm, in dark condition. The data were analyzed descriptively and statistically. The results showed that various density of Agrobacterium rhizogenes strain LB510 was affected the lenght of hairy roots induction of J. gendarussa Burm.f., but these was not effected toward lenght formation time and number of hairy root. The treatment of OD600 0.2 was the best treatment for hairy root induction on Justicia gendarussa Burm. f. This data could be used for optimized the quality of methode of hairy root induction. 
Production of Manooligomannan from Palm Kernel Cake by Mannanase Produced from Streptomyces Cyaenus
Authors: Purnawan Awan , Yopi Yopi , Irawadi Tun Tedja
Published: April 2017

The increase of public attention to health has prompted researchers to look for new sources of functional food. Palm Cake Kernel (PKC) waste was abundant in Indonesia, Oligosaccharide has an important benefit for human health. Recently oligosaccharide is not only important as an artificial sweetener, but also as a functional food component. This study was aimed to produce oligo-mannan enzymatically from PKC waste using mannanase derived from of Streptomyces cyaenus isolates of indigenous Indonesia. The enzyme concentration was determined by enzyme activity assay while oligo-mannan content in the PKC was analyzed using TLC and HPLC. Mannanase enzyme activity of 1706 U/ml on the second day of agitation 200 rpm at a temperature of 30°C Hydrolysis of mannooligomannan by using mannanase produced by streptomyces cyaenus. The optimum mannanase enzyme activity obtained on day 2 with the value of the activity as much of 0.702 U/mL. The protein content of the 2nd day at an agitation speed of 150 rpm, 200 rpm, and 250 rpm, respectively, were 1783, 1950 and 2283 ppm. Streptomyces cyaenus is Indonesian original isolates potentially producing mannanase that can produce mannooligomannan.
Physical Confirmation and Comparative Genomics of the RatMammary carcinoma susceptibility 3Quantitative Trait Locus
Authors: Le Saasha , Martin Zachary C , Samuelson David J
Published: April 2017

Human breast and rat mammary cancer susceptibility are complex phenotypes where complete sets of risk associated loci remain to be identified for both species. We tested multiple congenic rat strains to physically confirm and positionally map rat Mammary carcinoma susceptibility 3 (Mcs3)—a mammary cancer resistance allele previously predicted at Rattus norvegicus chromosome 1 (RNO1). The mammary cancer susceptible Wistar Furth (WF) strain was the recipient, and the mammary cancer resistant Copenhagen (Cop) strain was the RNO1-segment donor for congenics. Inbred WF females averaged 6.3 carcinogen-induced mammary carcinomas per rat. Two WF.Cop congenic strains averaged 2.8 and 3.4 mammary carcinomas per rat, which confirmed Mcs3 as an independently acting allele. Two other WF.Cop congenic strains averaged 6.6 and 8.1 mammary carcinomas per rat, and, thus, did not contain Mcs3. Rat Mcs3 was delimited to 27.8 Mb of RNO1 from rs8149408 to rs105131702 (RNO1:143700228-171517317 of RGSC 6.0/rn6). Human genetic variants with p values for association to breast cancer risk below 10−7 had not been reported for Mcs3 orthologous loci; however, human variants located in Mcs3-orthologous regions with potential association to risk (10−7 < p < 10−3) were listed in some population-based studies. Further, rat Mcs3 contains sequence orthologous to human 11q13/14—a region frequently amplified in female breast cancer. We conclude that Mcs3 is an independently acting mammary carcinoma resistance allele. Human population-based, genome-targeted association studies interrogating Mcs3 orthologous loci may yield novel breast cancer risk associated variants and genes.
A Variational Bayes Genomic-Enabled Prediction Model with Genotype × Environment Interaction
Authors: Montesinos-López Osval A , Montesinos-López Abelardo , Crossa José , Montesinos-López José Cricelio , Luna-Vázquez Francisco Javier , Salinas-Ruiz Josafhat , Herrera-Morales José R , Buenrostro-Mariscal Raymundo
Published: April 2017

There are Bayesian and non-Bayesian genomic models that take into account G×E interactions. However, the computational cost of implementing Bayesian models is high, and becomes almost impossible when the number of genotypes, environments, and traits is very large, while, in non-Bayesian models, there are often important and unsolved convergence problems. The variational Bayes method is popular in machine learning, and, by approximating the probability distributions through optimization, it tends to be faster than Markov Chain Monte Carlo methods. For this reason, in this paper, we propose a new genomic variational Bayes version of the Bayesian genomic model with G×E using half-t priors on each standard deviation (SD) term to guarantee highly noninformative and posterior inferences that are not sensitive to the choice of hyper-parameters. We show the complete theoretical derivation of the full conditional and the variational posterior distributions, and their implementations. We used eight experimental genomic maize and wheat data sets to illustrate the new proposed variational Bayes approximation, and compared its predictions and implementation time with a standard Bayesian genomic model with G×E. Results indicated that prediction accuracies are slightly higher in the standard Bayesian model with G×E than in its variational counterpart, but, in terms of computation time, the variational Bayes genomic model with G×E is, in general, 10 times faster than the conventional Bayesian genomic model with G×E. For this reason, the proposed model may be a useful tool for researchers who need to predict and select genotypes in several environments.
Genome-Enabled Prediction of Breeding Values for Feedlot Average Daily Weight Gain in Nelore Cattle
Authors: Somavilla Adriana L , Regitano Luciana C A , Rosa Guilherme J M , Mokry Fabiana B , Mudadu Mauricio A , Tizioto Polyana C , Oliveira Priscila S N , Souza Marcela M , Coutinho Luiz L , Munari Danísio P
Published: April 2017

Nelore is the most economically important cattle breed in Brazil, and the use of genetically improved animals has contributed to increased beef production efficiency. The Brazilian beef feedlot industry has grown considerably in the last decade, so the selection of animals with higher growth rates on feedlot has become quite important. Genomic selection (GS) could be used to reduce generation intervals and improve the rate of genetic gains. The aim of this study was to evaluate the prediction of genomic-estimated breeding values (GEBV) for average daily weight gain (ADG) in 718 feedlot-finished Nelore steers. Analyses of three Bayesian model specifications [Bayesian GBLUP (BGBLUP), BayesA, and BayesCπ] were performed with four genotype panels [Illumina BovineHD BeadChip, TagSNPs, and GeneSeek High- and Low-density indicus (HDi and LDi, respectively)]. Estimates of Pearson correlations, regression coefficients, and mean squared errors were used to assess accuracy and bias of predictions. Overall, the BayesCπ model resulted in less biased predictions. Accuracies ranged from 0.18 to 0.27, which are reasonable values given the heritability estimates (from 0.40 to 0.44) and sample size (568 animals in the training population). Furthermore, results from Bos taurus indicus panels were as informative as those from Illumina BovineHD, indicating that they could be used to implement GS at lower costs.
EKONOMINĖS PRIDĖTINĖS VERTĖS MAKSIMIZAVIMU GRINDŽIAMI AKCINIŲ BENDROVIŲ KAPITALO STRUKTŪROS FORMAVIMO SPRENDIMAI
Authors: Aleknevičienė Vilija , Basevičiūtė Inga
Published: April 2017

Straipsnyje pateikiama EVA maksimizavimu grindžiama akcinių bendrovių kapitalo struktūros formavimo metodika ir jos tikrinimas pasirinktose Lietuvos pieno perdirbimo akcinėse bendrovėse. Ankstesnių mokslinių tyrimų analizė parodė, kad pastaruoju metu vis didesnis dėmesys, priimant finansinius sprendimus įmonėje, iš jų ir kapitalo struktūros formavimo, skiriamas ne apskaitiniu pelnu, o įmonės verte grįstiems rodikliams. Nepaisant to, kad dauguma mokslininkų EVA rodiklį laiko tinkamu tikslinės (optimalios) kapitalo struktūros paieškai, yra tyrimų, paneigiančių šio rodiklio naudojimo tinkamumą ilgalaikiams finansiniams sprendimams priimti. Tyrime naudojami 2004–2014 m. Lietuvos pieno perdirbimo akcinių bendrovių, Baltijos vertybinių popierių rinkos ir Moody‘s kreditų reitingų agentūros duomenys. Nuosavo ir skolinto kapitalo kainai apskaičiuoti pasitelkiamas CAPM. Nuosavo kapitalo beta modeliuojamoms kapitalo struktūroms išreiškiama per vidutinę turto betą. Skolinto kapitalo betai apskaičiuoti pasitelkiami finansinių skolų ir finansinių sąnaudų duomenys, Cohen (2007) skolos betos apskaičiavimo formulė ir regresijos lygtys modeliuojamoms kapitalo struktūroms. EVA apskaičiuota kaip NOPAT ir kapitalo kaštų skirtumas. Tyrime naudotas vidutinis EBIT, pakoreguotas palūkanų suma, apskaičiuota modeliuojamoms kapitalo struktūroms, ir vidutinis investuotas kapitalas tiriamuoju laikotarpiu. Tyrimo rezultatai parodė, kad Lietuvos pieno perdirbimo akcinių bendrovių tikslinės kapitalo struktūros yra skirtingos. Dalis akcinių bendrovių, siekdamos maksimizuoti EVA, turi padidinti finansinį svertą, dalis – sumažinti. Vienas pagrindinių skirtingos tikslinės kapitalo struktūros veiksnių – skirtinga sisteminė, ypač verslo, rizika, kurios vertinimas pagrįstas rinkos duomenimis. Esant nepakankamai efektyviai rinkai riziką geriau vertinti naudojant apskaitos duomenis, nes NOPAT variacijos koeficientas stipriai neigiamai koreliuoja su tirtų akcinių bendrovių tiksline kapitalo struktūra.
Ionic liquid-based cloud-point extraction of quercetin for its sensitive HPLC–UV determination in juice samples
Authors: Rasoolzadeh Fahimeh , Hashemi Payman , Nazari Serenjeh Fariba
Published: April 2017

An ionic liquid-based cloud-point extraction (IL-CPE) method was developed for the extraction of quercetin in juice samples before its determination by high-performance liquid chromatography (HPLC). 1-Butyl-3-methylimidazolium hexafluorophosphate ([BMIM][PF6]) was used as the ionic liquid. The cloud-point extraction parameters such as sample pH, extraction temperature, extraction time, amount of ionic liquid, extraction volume, and salt concentration were carefully studied and optimized for the achievement of maximum extraction recovery. Under the optimized conditions, i.e., 20 min heating at 40 °C, 100 μL IL volume, pH 2.0, and no salt addition, a mean recovery of 92.5% and an enrichment factor of 20 were obtained for quercetin. Relative standard deviation of the method was 3.76% for 6 replicates, and the calculated detection limit (3σ) of quercetin was 0.002 mg L−1. The method, coupled to HPLC was successfully applied to the sensitive determination of quercetin in apple and gapes juice samples with quantitative recoveries.
Random Graphs' Robustness in Random Environment
Authors: Leri Marina , Pavlov Yury
Published: April 2017

We consider configuration graphs the vertex degrees of which are independent and  follow the power-law distribution. Random graphs dynamics takes place in a random  environment with the parameter of vertex degree distribution following  uniform distributions on finite fixed intervals. As the number of vertices tends  to infinity the limit distributions of the maximum vertex degree and the number  of vertices with a given degree were obtained. By computer simulations we study  the robustness of those graphs from the viewpoints of link saving and node survival  in the two cases of the destruction process: the ``targeted attack'' and the  ``random breakdown''. We obtained and compared the results under the conditions that  the vertex degree distribution was averaged with respect to the distribution of the  power-law parameter or that the values of the parameter were drawn from the uniform  distribution separately for each vertex.
Social representations and information security of children and adolescents: the point of view of teachers (Part 1)
Authors: Bovina I.B. , Dvoryanchikov N.V. , Gayamova S. , Milekhin A.V. , Budykin S.V.
Published: April 2017

The focus of attention of the authors is the consideration of information security of children and adolescents as the object of social representations. Discusses the need for the theory of social representations to develop prophylactic and preventive programs in the field of information security of children and adolescents, in particular, says that the effectiveness of prevention and preventive programs is determined by how this information is understood by the target group, through what filters it passes. Briefly outlines the main provisions of the theory of social representations, discusses the functions of social representations, the mechanism of action ideas. Analyzed in a few studies, the focus of which was the presentation on new technologies, particularly mobile phones and the Internet. Presents the results of a series of studies devoted to the study of information security of children and adolescents, including the results of the first part of a research project dedicated to the analysis of how parents and teachers understand information security and what strategies to protect children and adolescents from dangerous information they are ready to use.
Physiological characteristics of regulation of emotional responses among specialists of extreme profile
Authors: Kovaleva M.E. , Bulygina V.G.
Published: April 2017

The results of the examination psychophysiological mechanisms of coping with emotional reactions in stressful situations of the specialists of extreme profile are presented. The integrated biofeedback protocol using various functional tests has been developed. Statistical clustering method k-means was used; validation of the differences between the resulting clusters was carried out using one-way ANOVA. The internal consistency of various indicators of the autonomic and central nervous systems was revealed by the pairwise Pearson's correlation coefficient. Target variables for the mathematical analysis were: relative powers of alpha, theta, beta 1 and beta 2 rhythms, HR, HF, LF, VLF, RR, VS, LF/HF, TP, IC, SNCA, ASV, GSR. Multiple relationships between different levels of regulation of emotional state, the flexible use of different coping strategies, the ability to create new mechanisms of regulation in accordance with the objective and high braking performance the emotional state after the termination of the stressors was detected in the group with high stress sustainability. The group with low stress sustainability has been described by the opposite pattern.
On the question of psychological support of professional activity of law enforcement officers with mental dysfunctional States
Authors: Enina V. , Enin K.
Published: April 2017

In article the analysis of essence of the concept of mental dysfunctional state law enforcement officers, forming in the course of professional activity and its significance in the system of psychological support of the proposed classification of the typical dysfunctional mental States, defined basic criteria for evaluating mental dysfunctional States and test methods for the diagnostic evaluation of qualitative and quantitative indicators. The necessity to determine the level of activity and the polarity of mental dysfunctional States in order to develop a differentiated approach for development of further corrective measures. The authors recommended the most optimal method of psychological influence in the course of psychological support of professional activity of law enforcement officers with mental dysfunctional States. Shows the main advantages and features of socio-psychological training in comparison with the known traditional methods of psychotherapy.
Peculiarities of self-regulation of extreme profile specialists
Authors: Kabanova T.N. , Pleshakova E. , Dubinsky A.A. , Vasilchenko A.
Published: April 2017

Individually-psychological characteristics were studied and profiles of the styles of self-regulation of the employees engaged in hazardous were determined. The mainly group consisted of 30 men aged 21 to 60 years, who are specialists of dangerous professions. The comparison group included 30 men from 22 to 60 years, whose professional activity was not associated with risk. The following methods were used: questionnaire "Style of self-regulation of behavior" by V. I. Morosanova; questionnaire of self-control (H. Grasmik, 1993, adaptation Bulygina V. G., Abdrazakova A. M., 2009); the questionnaire BIS/BAS, used to study the sensitivity to punishment and reward; the questionnaire formal-dynamic properties of individuality by V. M. Rusalov; the aggression questionnaire by A. Buss and M. Perry (adaptation Enikolopov S. N., Cybulski N. P., 2007); the scale of anxiety Charles D. Spielberger (State-Trait Anxiety Inventory – STAI); personal questionnaire of the G. and S. Eysenck – EPQ.
It was found that specialists hazardous professions are distinguished by: a higher level of development of the regulatory flexibility and individual system of conscious self-regulation activity; higher levels of extroversion, communication activity, the total adaptability; a lower level of reactive anxiety, trait anxiety and general emotional. Moreover, impulsiveness, egocentrism, lack of restraint and physical activity in the structure of self-monitoring specialists of dangerous professions associated with high levels of affective component of aggression and incoherence of parts of the process of self-regulation. There were allocated a 3 profile of self-regulation in specialists of dangerous professions: a) a high level of self-regulation – coupled with a high intellectual and physical development, the highest level of adaptability and general activity; b) medium – rapid response to emerging changes in the situation, the successful production alternatives, greater flexibility in the process of communicating with less intellectual and physical activity; c) low – the most developed stage of self-regulation is assessment of results with low rates of formal-dynamic properties of individuality and adaptability at the same time.
Characteristics of psychological violence (mobbing) in terms of emigration
Authors: Kovalchishina N.I.
Published: April 2017

In the article the problem of psychological violence (mobbing) in organizations, his psychological characteristics in emigration.
Analyzes the types of mobbing, its negative influence on the personality, negative consequences which not only affect physical and psychological health, but also lead to physical diseases, and suicide.
The author emphasizes that in conditions of exile (in Israel) psychological violence is experienced more acutely and is characterized by a prolonged depressed state. One important reason for this situation is the decline of the former social status of the emigrant, being able to quickly inclusion in the new society, loss of important social ties, the need to adopt different social norms, sometimes contradicting previously established views. Against the background of such negative phenomena in humans appear aggression, desire to dominate at any cost to regain lost status.
The problem of mobbing in the modern world is very important and requires a robust approach at the state level. That psychological safety is a condition for ensuring the formation and development of functional comfort, maintaining a high level of personal emotional security and social-psychological skills, optimization of reserve possibilities of the person in activities.
The problem of the differentiation of expert attitudes of emotional states and affect
Authors: Morozova M. , Savina O.
Published: April 2017

The article presents the results of a study of trust between employees of a penal colony (inspectors and employees of the production zone), and women who are serving sentences for the crimes of 1) small and moderate, 2) such grave and particularly grave crimes. There were used a modification of the methods of assessment of trust/distrust by A. B. Kupreychenko, M. Rosenberg's Faith in People Scale, Acceptance of Others Scale by William F. Fey and J. Campbell’s Benevolence Scale. The fact of greater confidence on the part of employees of the production department to the women who are serving a sentence for a grave or especially grave crime was fixed, it was explained the specifics of their interaction in the work. The general trend to exercise greater trust by inmates to employees of the penal system was detected than their response reaction that appear of a greater degree of distrust.
The power of imagination / The weakness of dating: on two origins of autobiographical memory distortion
Authors: Nurkova V.V. , Vasilenko D.
Published: April 2017

The article focuses on issues of autobiographical memory malleability which are of high relevance to forensic practice. Taking into account both single case report and mass studies we revealed that time is the weakest aspect of autobiographical recollection. Namely, dating of past event and ordering of event components are prone to memory distortion to the maximum extent. Paradoxically, it coincides with high confidence in accuracy of event recalled. Than we shifted to the most discussed in the relevant literature mechanism of memory transformation i.e. imagination inflation. This mechanism consists of mistaking just imagined event for a real one. We also noted that high subjective probability of imagined event and reliable source of misinformation make significant impact into memory transformation.
Классификационная схема инноваций
Authors: Гулевская Юлия Андреевна
Published: April 2017

В статье аккумулированы ключевые классификационные критерии инноваций отечественных и зарубежных экономистов, а также предложен концептуально новый подход автора к группировке нововведений. В основу классификационной схемы инноваций заложено более 30 структурирующих признаков, которые позволяют определить место нововведений, их характеристики, возможности и др. Представленная классификационная схема имеет не только теоретическую значимость, но и практическое применение с точки зрения привлечения финансирования: на основании классификационной системы потенциальными инвесторами и другими финансовыми институтами поддержки проводится оценка инновационных проектов и заключаются выводы о целесообразности их запуска, дальнейшей реализации или трансформации.
Классификация и сущность современных типов организации в России
Authors: Бородянский Борис Михайлович Борис Михайлович
Published: April 2017

Развитие высоких технологий и новых веяний в теории управления позволяет организациям достигать новых вершин эффективности и успеха невиданными ранее средствами. При этом, эти же факторы заставляют компании искать новые возможности для выживания на рынке, ставят новые испытания перед организациями. Организации меняются, приобретая черты виртуальности, распределенности, децентрализованности. Для этих новых современных видов организаций (виртуальных, научающихся, основанных на знаниях) коммуникации и управление знаниями будет играть ключевую роль. Именно поэтому необходимо понять, как таким организациям выстраивать свои внутренние системы, какие практики и инструменты использовать для повышения осведомленности сотрудников о том, что происходит в компании, как управлять знаниями и организацией в целом.
Основные тенденции в сфере кредитования физических лиц в России
Authors: Багаутдинова Инна Валерьевна , Палаткин Юрий Сергеевич , Токарева Гузель Фарисовна
Published: April 2017

В статье анализируются основные тенденции в сфере кредитования физических лиц, показаны факторы их возникновения и значение в дальнейшем прогнозировании развития кредитных услуг коммерческих банков в Российской Федерации. Раскрыты основные проблемы и показаны перспективы совершенствования организации кредитования населения.
Erratum: Non-marine fishes of the late Santonian Milk River Formation of Alberta, Canada – evidence from vertebrate microfossil localities
Authors: Brinkman Don B , Neuman Andrew , Divay Julien
Published: April 2017

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Daesh: Riches and Self-Alienation in a Fledging Pseudo-State
Authors: Braunfisch Hans Albert
Published: April 2017

Daesh, or Islamic State, holds captive the fears of populations the world over. However, with the advent of this new type of terror organization functioning as a pseudo-state, the approach to eliminating it must also be adapted, but in order to eliminate such a threat, it must first be understood. As of now, the understanding of Daesh widely varies depending upon the source. They are likened to other terror organizations, insurrections, unrecognized states, and caliphates of antiquity. To make the concept and understanding of Daesh more comprehensible to members of the private sector, the author utilizes a framework common for consultancies and management teams, the S.W.O.T. Analysis, to depict the organization’s assets, shortcomings, potentials for growth, and hazards. Following this analysis, the author paints Daesh as a product of its environment. With instability in the Middle East, a large population of disgruntled, young men, and globalization via social media, Daesh has become not only a pseudo-state to destroy, but an ideology that permeates inexistent cyber borders. As a result, implications for policy revision and reflection are vital for preventative measures. The author suggests leaders’ future approaches involve less armed intervention to preserve governments and greater investment in aid. These two methods create a stable environment in which the populace can focus on economic and personal development, as opposed to ideological conflict.