bluuebunny/crossref_metadata_2025 huggingface dataset:
Impact of climate change on future bioclimatic potential and residential building thermal and energy performance in India
Authors: Kishore Naveen
Published: February 2021

This paper aims to investigate the implication of present and future bioclimatic potential of passive heating and cooling design strategies for climate change scenarios of five locations covering all climate zones of India. Weather data for future climate change were developed for A2 (medium-high) scenario of the Intergovernmental Panel on Climate Change (IPCC) for four time slices, namely TMY (Typical Meteorological Year), 2020, 2050 and 2080. A case study residential building was used for calibration and validation of the bioclimatic potential using EnergyPlus simulation. Results show a strong correlation between the annual bioclimatic summer and winter discomfort hours and the corresponding annual cooling and heating energy load for the changing climate scenarios. Results also show an overall increase in annual cooling energy load, over and above the base case, ranging from 18% to 89% among the five cities in 2020; 32% to 132% in 2050 and 58% to 184% in 2080 if residential buildings continue to be operated in the same manner as it is done today without passive strategies. The use of passive strategies may reduce the annual cooling load by about 50%– 60% in residential buildings in future.
The policing of subway fare evasion in postindustrial Los Angeles
Authors: Johnson Lallen T , Patterson Evelyn J
Published: February 2021

According to the postindustrial policing thesis, cities that use cultural development strategies to attract new residents and visitors rely on order maintenance policing tactics to reinforce middle-class perspectives of safety and civility. This study applies that thesis to understand how shifting social structural dynamics influence the policing of fare evasion across the Los Angeles Metropolitan Transit Authority subway system. In accordance with the postindustrial perspective, results indicate that order maintenance policing is most intense at stations located in gentrifying neighborhoods; and, at the average station this form of policing is overwhelmingly directed towards Black and Latinx riders. Collectively, study findings suggest that mass transit in gentrifying areas represents a disputed resource that is policed in the interests of urban revitalization. Moreover, this treatment of fare evasion joins a growing body of penal remedies that expands the sphere of public social control, and further marginalizes disenfranchised groups.
Evaluation of the mechanical properties of Inconel 718 to SCM 440 dissimilar friction welding through real-time monitoring of the acoustic emission system
Authors: Kong Yu Sik , Cheepu Muralimohan , Lee Jin-Kyung
Published: February 2021

Friction welding was chosen for its versatility in the joining of dissimilar materials with high quality. The aim of this study is to determine the optimal welding conditions for attaining quality joints by using online monitoring of acoustic emission system signals. During friction welding, the formation of cracks, defects, or any abnormalities in the joining process which have a detrimental effect on the joints quality was identified. The most widely used materials in the aerospace industry—Inconel 718 and molybdenum steel—were joined by friction welding. The precision of the joints, internal defects, and quality are major concerns for aerospace parts. The results of the present research determined the optimal welding conditions for high tensile strength by nondestructively inducing acoustic emission signals. During friction time and upset time periods, the typical waveforms and frequency spectrum of the acoustic emission signals were recorded, and their energy level, average frequency, cumulative count, and amplitude were analyzed. Both cumulative count and amplitude were found to be useful parameters for deriving the optimal welding conditions. In the initial stage of friction welding, a very high voltage of continuous form was generated with frequency characteristics of 0.44 MHz and 0.54 MHz. The signals generated during the upset stage had a low voltage, but a very high frequency of 1.56 MHz and 1.74 MHz with a burst-type signal. The amplitude of the signal generated for the optimally welded joints was about 100 dB at the friction time and about 45 dB at the upset time.
Assessment of scatter on material properties and its influence on formability in hole expansion
Authors: Miranda SS , Cruz DJ , Amaral RL , Santos AD , César de Sá J , Fernandes JV
Published: February 2021

The plastic deformation included in the technological processes of sheet metal forming allows the production of different components with different geometries. Therefore, the formability of metallic materials is an essential feature in stamping processes. One of the inevitable scattering sources when considering these processes is the variability of material properties, which can change from coil to coil, from batch to batch and from supplier to supplier. This constitutes a significant obstacle in improving the quality of any manufacturing process. The current study investigates the formability and the mechanical characterization of a defined advanced high strength steel grade, considering different suppliers, coils, and batches in order to evaluate its influence on the results of the sheet metal forming process. A microstructure analysis is also considered to understand the impact of micro-scale variables (e.g. grain size) in macro-scale behavior. Additionally, numerical simulations were taken into consideration to evaluate the influence of mechanical characterization in the results.
Studies on structural, mechanical and erosive wear properties of ZA-27 alloy-based micro-nanocomposites
Authors: Vencl Aleksandar , Kandeva Mara , Zadorozhnaya Elena , Svoboda Petr , Michalec Michal , Milivojević Aleksandar , Trdan Uroš
Published: February 2021

Metal matrix nanocomposites represent a relatively new class of material, which is still being extensively investigated. Most of the studies, however, are devoted to aluminium- or magnesium-based nanocomposites. A limited number of studies focus on zinc alloy base nanocomposites, with fewer still concentrating on zinc alloy base micro-nanocomposites. In addition, most of the tribological studies investigate adhesive or abrasive wear resistance, whereas studies of erosive wear resistance lag well behind. It was previously shown that the presence of nanoparticles in ZA-27 alloy-based nanocomposites led to a slight increase in erosive wear resistance. Upon discovering that, the aim became to produce micro-nanocomposites that would retain the positive effect of nanoparticles, while further elevating performance, by combining microparticles with nanoparticles. The ZA-27 alloy-based micro-nanocomposites were reinforced with 3 wt. % Al2O3 microparticles (particle size approx. 36 μm) and with four different amounts (0.3, 0.5, 0.7 and 1 wt. %) of Al2O3 nanoparticles (particle size 20–30 nm). Tested materials were produced by the compocasting process, with mechanical alloying pre-processing. Solid particle erosive wear testing, with particle impact angle of 90°, showed that all micro-nanocomposites had significantly increased wear resistance in comparison to the reference material.
Effects of cyclic ageing on the tensile properties and diffusion coefficients of an epoxy-based adhesive
Authors: da Costa JA , Akhavan-Safar A , Marques EAS , Carbas RJC , da Silva LFM
Published: February 2021

In real practice, adhesively bonded structures are usually exposed to cyclic environmental conditions. However, cyclic ageing processes are relatively unexplored. The aim of this study is to consider the effect of cyclic ageing on the rate of water uptake and the drying process in an epoxy-based adhesive. Fick’s law was considered to estimate the water diffusion coefficients for the ageing and the drying steps at different cycles. Different cyclic ageing times have been considered in the ageing procedure. Dogbone shape specimens were also manufactured and subjected to cyclic aging to investigate the tensile properties of the tested adhesive as a function of aging cycles. The gravimetric results showed that the rate of water uptake and drying is mainly a function of the level of water uptake of the first ageing cycle. Tensile test results showed that the maximum water content increases with each subsequent ageing cycle. It was also found that the Young’s modulus and the tensile strength of the adhesive decreased significantly after the initial ageing cycle, but all subsequent ageing cycles have considerably less influence on the mechanical properties of the adhesive.
Hostile emotions: An exploratory study of far-right online commenters and their emotional connection to traditional and alternative news media
Authors: Ihlebæk Karoline Andrea , Holter Carina Riborg
Published: February 2021

In this article, we explore media use through the perspective of emotions. We specifically focus on a contested group of media users, namely those who engage in uncivil online behaviour and have had one or several comments deleted by moderators due to xenophobic and racist content. Our point of departure is that the informants represent a particularly engaged yet controversial audience. Based on theoretical perspectives on ‘hostile emotions’ like anger and fear and how the news media function as ‘emotional regimes’, we explore how the informants talk about their worldview and how it affects their media choices. We argue that political fear constitutes a powerful part of the informants’ narratives, which again influences their media use. Even though they are highly sceptical and suspicious, the participants in the study seek information from a wide selection of traditional and alternative sources where their worldview is both contested and confirmed. Furthermore, the strong fear expressed by informants constitute an important element of the anger they feel towards the established news media. This particular anger is structured around the notion of objective reporting that they consider highly provocative, both factually and emotionally, as it does not match how they experience the world around them.
Eating disorders and the orthodontist: Diagnosis, considerations and referral
Authors: Smorthit Kelly , Sawbridge David , Fitzgerald Rhian
Published: February 2021

Background:

Eating disorders are relatively common mental health disorders in Western European and North American populations. The peak incidence occurs within the adolescent years, which correlates with the largest orthodontic patient population. The morbidity associated with these psychological conditions is significant, and has a direct impact upon patient well-being, orthodontic outcomes and the success of treatment. Therefore, it is of relevance to the orthodontist to be aware of potential presenting features of these conditions, when and where to seek advice, and how such disorders may impact upon orthodontic outcomes.

Methods:

Articles published on PUBMED and MEDLINE relevant to orthodontics and eating disorders were reviewed. Key information was extracted, and the relevant evidence for the orthodontist summarised.

Results:

Eating disorders may present to the orthodontist in specialist or hospital practice, either undiagnosed or as a co-morbidity. Orthodontists may benefit from an appreciation of these potential diagnoses, the orthodontic implications and to have the confidence to refer their patients to the necessary services.

Limitations:

There is little existing research in this area.

Conclusions:

These conditions have a significant impact on patient morbidity and mortality. This cohort of patients is not suitable for orthodontic treatment while their disease is active. The impact of a developing eating disorder can adversely affect orthodontic treatment.
The ethics of experimental research employing intrusive technologies in tourism: A collaborative ethnography perspective
Authors: Tham Aaron , Schaffer Vikki , Sinay Laura
Published: February 2021

This study probes the ethics of intrusive technologies for experimental research in tourism, through the lens of collaborative ethnography. Amidst the increasing uptake of technology to assess participant responses, the role of ethics in an experimental setting has received scant attention in tourism and hospitality. While intrusive technologies such as eye tracking, skin sensors and neuroscience headgear become more ubiquitous, the ethical boundaries of using such equipment are increasingly blurred and inconsistently approved. Seeking convergence of ethics concerning intrusive technologies is complicated when framing political spaces, target audiences and management of data obtained. Rather than view the role of intrusive technologies as a dichotomous outcome of ethical or unethical approaches, this paper argues that ethics needs to be contextually embedded with increased collaboration and co-creation in the application preparation and approval process.
Strategic responses to COVID-19: The case of tour operators in Vietnam
Authors: Do Binh , Nguyen Ninh , D’Souza Clare , Bui Huu Duc , Nguyen Thi Nguyen Hong
Published: February 2021

The COVID-19 outbreak has challenged the global tourism economy. It has particularly threatened the survival of tourism firms in developing countries especially those with the greatest growth of international visitors, such as Vietnam. This study aims to highlight the impact of COVID-19 on tour operators in Vietnam and explore their strategic responses to the crisis. Data were obtained from a recent survey initiated by the National Tourism Advisory Board and 32 in-depth interviews with managers of selected firms. The survey results demonstrate that the key influences of COVID-19 include plummeting revenue, increased costs, and employee redundancy. Furthermore, the majority of tour operators are aware of the need for restructuring and expect financial support from the government to overcome the crisis. The findings from the interviews reveal that tour operators focus more on short and medium-term strategies (i.e., retrenchment, persevering, and exiting) rather than long-term planning (i.e., innovating) in response to COVID-19. This study advances the knowledge and application of response-to-crisis strategies in tourism research, and its findings have practical implications for managers and policymakers in times of exceptional crisis like the COVID-19 pandemic.
Breaking out of the policy enclave approach to child labour in sub-Saharan African agriculture
Authors: Sabates-Wheeler Rachel , Sumberg James
Published: February 2021

This article is framed by the tension between a substantial universalising framework of global instruments on workers’ rights and child labour on one hand, and their outsourced implementation through the social policy enclaves of transnational corporations on the other hand. It uses the concept of ‘social policy enclaves’ to explore this tension and how it might be resolved to the benefit of children who work in African agriculture. To do this, the article steps back from dominant discourses around child labour, and examines how a re-framing of children’s involvement in African agriculture, from labour to work, might enhance understanding of the forms, prevalence, drivers and dynamics of their involvement in work that is harmful. A deeper understanding of these issues should help to inform a revitalised universal approach to social policy in respect to children’s work.
Eulerian–Lagrangian CFD-microphysics modeling of a near-field contrail from a realistic turbofan
Authors: Cantin Sébastien , Chouak Mohamed , Morency François , Garnier François
Published: February 2021

Aircraft contrails contribute to climate change through global radiative forcing. As part of the general effort aimed at developing reliable decision-making tools, this paper demonstrates the feasibility of implementing a Lagrangian ice microphysical module in a commercial CFD code to characterize the early development of near-field contrails. While engine jets are highly parameterized in most existing models in a way that neglects the nozzle exit-related aspects, our model accounts for the geometric complexity of modern turbofan exhausts. The modeling strategy is based on three-dimensional URANS simulations of an aircraft nozzle exit involving a bypass and a core jet (Eulerian gas phase). Solid soot and ice particles (dispersed phase) are individually tracked using a Lagrangian approach. The implemented microphysical module accounts for the main process of water-vapor condensation on pre-activated soot particles known as heterogeneous condensation. The predictive capabilities of the proposed model are demonstrated through a comprehensive validation set based on the jet-flow dynamics and turbulence statistics in the case of compressible, turbulent coaxial jets. Simulations of contrail formation from a realistic nozzle-exit geometry of the CFM56-3 engine (short-cowl nozzle delivering a dual stream jet with a bypass rate of 5.3) were also carried out in typical cruise flight conditions ensuring contrail formation. The model provides reliable predictions in terms of the plume dilution and ice-particle properties as compared to available in-flight and numerical data. Such a model can then be used to characterize the impact of nozzle-exit parameters on the optical and microphysical properties of near-field contrails.
Researching event-centred projects: Showcasing grounded aesthetics
Authors: Howard Frances
Published: February 2021

Showcasing plays a fundamental role in arts education programmes. This paper presents an approach to research scenarios which explore ‘event-centred’ projects. Drawing on arts-based methodologies and research projects, this approach could be extended to the study of seasonal rituals, festivals and other types of organisational settings in which creative work culminates in some type of public display. This paper defines the key features of this method, which draw on Paul Willis’ concept of ‘grounded aesthetics’ and Sarah Pink’s work on the sensorial and embodied experience. I discuss the experimentation with various digital media and documentation strategies which adopt a participatory and collaborative perspective. I focus on how the sensorial, multimodal and collaborative approaches to ethnography are used within event-centred research projects which complement more ‘traditional’ ethnographic approaches. Finally, this paper offers a methodological contribution regarding how to unpack the ‘grounded aesthetics’ of specific contexts and communities.
Tourist’s mobilities: Walking, cycling, driving and waiting
Authors: Hannam Kevin , Butler Gareth , Witte Alexandra , Zuev Dennis
Published: February 2021

This commentary reviews recent research in terms of tourist’s mobilities in terms practices of walking, cycling and driving. It concludes by reflecting on the contemporary lock down of travel in terms of the global pandemic and its consequences for waiting, stillness and immobility – particularly in terms of flying.
Ancient human DNA: A history of hype (then and now)
Authors: Jones Elizabeth D , Bösl Elsbeth
Published: February 2021

In this article on the history of ancient DNA research, we argue that the innovation of next-generation sequencing (NGS) of the early 2000s has ushered in a second hype cycle much like the first hype cycle the field experienced in the 1990s with the advent of the polymerase chain reaction (PCR). While the first hype cycle centered around the search for the oldest DNA, the field’s current optimism today promotes the rhetoric of revolution surrounding the study of ancient human gnomes. This is evidenced from written sources and personal interviews with researchers who feel the vast amount of data, the conclusions being made from this data, and the ever-increasing celebrity status of the field are perhaps moving too fast for their own good. Here, we use the concept of contamination, in both a literal and figurative understanding of the term, to explore the field’s continuities and disparities. We also argue that a number of additional, figurative interpretations of “contamination” are useful for navigating the current debate between geneticists and archaeologists regarding the origin, evolution, and migration of ancient humans across space and time. Our historical outlook on aDNA’s disciplinary development, we suggest, is necessary to accurately appreciate the state of the field, how it came to be, and where it might go in the future.
(Re)locating photojournalism within a transmedia economy: a case study on the meaning-making process with stories of female Boko Haram survivors
Authors: De La Presa Lucia , Elvira Ruiz Paloma
Published: February 2021

This study explores the representations of female captives and survivors of Boko Haram in what the authors define as a transmedia project formed by an ensemble of interconnected multi-modal/media productions circulated through off- and online spaces, and merging photojournalism and humanitarian markets. The authors draw on semiotic analytical tools in unravelling the process of meaning-making and point to a trend of spectacle renewal in which recycled textual and visual elements function as forms of (self) promotion within the transmedia project. In its response to neoliberal logics of production and circulation of culture, this transmedia project ends up reproducing reductionist portrayals of Boko Horam (ex-)captives and empowering Western producers and consumers through representations that fortify a gendered, neocolonial relationship. This research problematizes the moralistic narratives that support this transmedia economy and proposes alternative modes of sharing and consuming photojournalism stories in order to encourage more critical engagement.
Graphical viewing at a distance: graphical analytics as a method for the investigation of illustrated books
Authors: Kilchör Fabienne , Lehmann Jörg
Published: February 2021

In this research article, graphical analytics is presented as a method for the investigation of page/layout- and image-based materials. This approach is used to analyse image composition, image constellations and the layout of the examined books, and it facilitates a comparison across several books within a single visualization. The methodology is introduced and the epistemology explained, along with concepts such as framework, simulative and heuristic models, and image constellations. Methodological steps like the establishment of the data set, the collection of specific data, the organization of the information architecture, and the design of the display of these data are explained. The method is illustrated through a case study on nine illustrated books on non-human primates. This material is analysed according to given research questions on the proximity of non-human primates and human beings being depicted in the images of these books, and on the differences between the illustrated books with respect to their target audiences. The findings of our graphical analytics reveal patterns of proximity between humans and non-human primates as well as the iconology of the Book of Genesis in the pictorial and textual materials used by these illustrated books. This contribution presents an introduction to graphical analytics with an exemplary application.
Expressions of masculine identity through sports-based reminiscence: An ethnographic study with community-dwelling men with dementia
Authors: Sass Cara , Surr Claire , Lozano-Sufrategui Lorena
Published: February 2021

Background

Despite increasing numbers of men living in isolation with dementia in the community, uptake of supportive interventions remains low. This may be because of limited availability of activities suited to men’s interests. One organisation reporting higher attendance from men is Sporting Memories, offering inclusive sports-based reminiscence and physical activities for men living with dementia. This study aimed to explore the impact of the Sporting Memories intervention on men living with dementia.

Method

This study was an ethnography employing techniques of participant observation, informal conversations and semi-structured interviews with group participants. Data were woven into a series of narratives using creative non-fiction, to bring life to the first-hand accounts of participants and experiences within a typical group setting.

Findings

The groups provided an environment for men with dementia to explore, reflect upon and reinforce their masculine identities through the subject of sport. Physical activities further facilitated this embodied demonstration for some, although this was not a feature of all sessions.

Conclusions

The content of Sporting Memories group sessions provides a vehicle for men to retain an important aspect of personhood. They also hold the potential to present opportunities for men to feel a sense of value by contributing to sessions in varied ways. Facilitators and volunteers require support and training to ensure this benefit is maintained.
Experiences of people with memory disorders and their spouse carers on influencing formal care: “They ask my wife questions that they should ask me”
Authors: Aaltonen Mari S , Martin-Matthews Anne , Pulkki Jutta M , Eskola Päivi , Jolanki Outi H
Published: February 2021

Background

People with memory disorders often need care and help from family carers and health and social care providers. Due to the deterioration of cognitive capacity and language skills, they may be unable to convey their thoughts and care preferences to other people. As a result, their agency may become restricted. We investigated the descriptions provided by people with memory disorders and spousal carers of their influence on care in encounters with formal care providers.

Methods

Qualitative thematic analysis was used to identify, analyze, and report themes that describe encounters with professionals in different social or healthcare environments. In-depth interview data were gathered from 19 spouse carers and 15 persons with memory disorders.

Findings

Three themes out of four describe how people with memory disorders and their spouse carers influence formal care: Acquiescence, negotiating care decisions, and taking control. The fourth theme describes lack of influence. People with memory disorders and their spouse carers have ways to influence care, but spouse carers identified more ways of doing so. Both either accepted and followed the care guidelines by the formal carers or took control of the situation and made their own decisions. Spouse carers also sought to influence care decisions through negotiations with formal carers. When formal carers’ decisions were experienced as inconsistent or the rationale of their actions difficult to follow, the possibilities to influence care were limited.

Conclusions

People with memory disorders and their family carers are often in a disadvantaged position as they lack power over the health and social care decision-making during the illness, which is often guided by structural factors. To support the agency of people with memory disorders and to promote shared decision-making, clarification of the service structure and clearer communication between the different parties involved in care are required.
Caregiver identity in care partners of persons living with mild cognitive impairment
Authors: Beatie Brooke E , Mackenzie Corey S , Funk Laura , Davidson Dylan , Koven Lesley , Reynolds Kristin A
Published: February 2021

Research on caregiver identity in the context of memory impairment has focused primarily on more advanced stages of the cognitive impairment trajectory (e.g., dementia caregivers), failing to capture the complex dynamics of early caregiver identity development (e.g., MCI; mild cognitive impairment caregivers). The aim of this study was to develop a nuanced understanding of how caregiver identity develops in family and friends of persons living with MCI. Using constructivist grounded theory (ConGT), this study explored caregiver identity development from 18 in-depth interviews with spouses ( n = 13), children ( n = 3), and friends ( n = 2) of persons recently diagnosed with MCI. The overarching themes influencing MCI caregiver identity development included MCI changes, care-related experiences, “caregiver” interpretation, and approach/avoidance coping. These themes influenced how participants primarily identified, represented as I am a caregiver, I am not a caregiver, or liminality (i.e., between their previous identity and a caregiver identity). Irrespective of their current self-identification, all conveyed thinking about their “future self,” as providing more intensive care. MCI caregiver identity development in family and friends is a fluid and evolving process. Nearly all participants had taken on care tasks, yet the majority of these individuals did not clearly identify as caregivers. Irrespective of how participants identified, they were engaging in care, and would likely benefit from support with navigating these changes and their new, ambiguous, and evolving roles.
“I am not a good enough caregiver, and it is my fault”: The complex self-concept of Vietnamese female caregivers in dementia care
Authors: Nguyen Trang T
Published: February 2021

In Vietnam, the majority of dementia caregivers are women. They play multiple social roles, confronting role conflicts, and caregiving burdens with insufficient social supports. Dementia caregiving alters their self-concepts, or who and how good they think they are. This secondary analysis study aims to explore self-concepts of Vietnamese female caregivers of people with dementia. In total, data of 21 face-to-face, semi-structured interviews, including six follow-up interviews, conducted with 13 Vietnamese female caregivers of people with dementia, were drawn from a larger study for analysis following the thematic coding procedure. Results showed that the self-concepts of female caregivers in dementia care were complex, contextualized, and manifested in different aspects. First, the guided self and the performed self emerged from the data as the key themes consistently shared by female caregivers. Their guided self was the self that their social norms and cultural traditions told them about who they should be, while their performed self was the self they demonstrated to the outside world. The mismatch between these two types of self (self-discrepancy) caused distress among caregivers. Second, caregivers’ self-concept was the combination of the three key types of the self: the moral self (a filial daughter or a responsible wife); the feminine self (a patient and graceful women); and the worthy self (a devoted and helpful caregiver). Understanding Vietnamese female caregivers’ self-concepts, self-discrepancy, and its impacts on their well-being can be used to inform the development of interventions and social services for this underserved group.
Managing expectations by projecting the future school: Observing the Nordic future school reports via temporal topologies
Authors: Hansen Petteri , Sivesind Kirsten , Thostrup Rune
Published: February 2021

This study focuses on the politics of time in education by analysing ‘The Future School’ reports published by Nordic state authorities between 2010 and 2015. Building on a system-theoretical understanding of social time, steering and second-order observations, we investigate how temporal political communication frames the future of Nordic basic education. By applying semantic analysis, we identified four temporal topologies according to which these reports deal with the future: (a) calculated futures based on future projections with numbers; (b) unpredictable futures based on future projections contrasting learning with adaptivity; (c) technology-determined futures; and (d) personalised futures based on child well-being. Whereas these topologies constitute a shared semantical base for discussing the future of school education, a comparison of the reports also reveals differences and paradoxes between the temporal topologies in the Nordic welfare state context.
Experimental and numerical investigation on control strategies for heave and pitch motion reduction of a catamaran
Authors: Zheng Linhe , Liu Zhilin , Li Guosheng , Yuan ShouZheng , Yang Songbai
Published: February 2021

In this study, simulations and experiments were conducted on reducing the heave and pitch motions of a catamaran. To serve as stability appendages, an actively controlled T-foil and flap were designed, including their dimensions and installation position on the catamaran. Based on the uncoupled analysis of the appendages, the following control strategies were adopted: the previously proposed resultant force and moment distribution with feedback by displacement (RFMD-D) and the newly developed resultant force and moment distribution with feedback by velocity (RFMD-V). These two control strategies were applied to an S-plane controller, and their performances were tested in simulations and experiments. Finally, a bare catamaran and catamaran with actively controlled appendages were towed in a towing tank, and the two control strategies were tested. The results showed that both control strategies are effective and that RFMD-V is more effective than RFMD-D.
Predictors of transfer behaviours in adult university students
Authors: Potter Charlie
Published: February 2021

Adult students are critical to addressing the college completion crisis. Retention and completion for adults lags behind students who enter college directly from high school. However, higher education has largely been built around service to younger high school graduates, and institutions are slow to change. A shift in focus to accommodate the needs and interests of adult learners will require additional research regarding the enrollment patterns and behaviours of adult students. This study uses quantitative methods and the Beginning Postsecondary Students 12/14 dataset to consider the role of transfer in the experience of the adult learner, with specific attention to the characteristics, demographics and experiences of adult transfer students as well as the predictors of reverse and lateral transfer behaviour in adult student populations.
A causal relationship between rheumatoid arthritis and bronchiectasis? A systematic review and meta-analysis
Authors: Wiater Rafal , Håkansson Kjell Erik Julius , Ulrik Charlotte Suppli
Published: February 2021

Rheumatoid arthritis (RA) is a chronic autoimmune disease primarily affecting joints but often also associated with lung involvement such as bronchiectasis (BE). The aim of the present systematic review and meta-analysis is to provide an update on the current evidence regarding the prevalence and association between RA and BE. This systematic review and meta-analysis was performed in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines with literature search using the terms ‘Bronchiectasis AND Rheumatoid Arthritis’ without a date limitation on PubMed during May 2020. A total of 28 studies fulfilled the predefined criteria and were included in the present review, with 19 being cross-sectional studies. Twenty-three studies were included in the meta-analysis. The pooled prevalence estimate was 2.69% (95% CI 1.63–4.42) in clinically defined BE, and 24.9% (95% CI 19.21–31.67) in radiologic disease. Many inconsistencies exist regarding potential risk factors for BE in RA patients such as gender, RA duration and severity, as both negative and positive associations have been reported. Although very little is known about possible causative mechanisms between RA and BE, potential pathways might be antigenic stimulation from pulmonary mucus and/or systemic inflammation from joint disease affecting the lungs. At present, the available evidence of bronchiectasis in patients with RA is insufficient to identify RA-associated risk factors for the development of BE, possibly apart from duration of RA, and, consequently, also to fully explore a possible causal relationship between the two disease. However, the increased prevalence of BE in RA patients warrants further studies to explore the association between RA and BE.
Dysregulated LncRNAs Act as Competitive Endogenous RNAs and Are Associated With Cervical Cancer Development in UYGHUR Women
Authors: Chen Yanxia , Chen Dong , Wang Jing , Zhang Yu , Zhang Ji , Chen Bing , Chen Yaru , Zhang Yi , Ma Cailing
Published: February 2021

Cervical cancer is one of the most malignant tumors in women, particularly those in rural and remote areas. Its underlying molecular mechanisms, including the functions of non-coding RNA (ncRNAs), require more extensive investigation. In this study, high throughput transcriptome sequencing (RNA-seq) was used to identify differentially expressed lncRNAs and mRNAs in normal, cervical intraepithelial neoplasia and cervical cancer tissues from Uyghur women in western China. Dysregulated lncRNAs were found to extensively participate in cervical cancer development, including viral carcinogenesis, cell cycle and cytokine-cytokine receptor signaling. Two miRNA-host lncRNAs, LINC00925 and MIR155HG, showed elevated expression in cervical cancer samples, but prolonged the survival time of cervical cancer patients. The 2 mature miRNAs of the above 2 lncRNAs, miR-9 and miR-155, also showed similar features in cervical cancer. In addition, we identified 545 lncRNAs with potential functions in regulating these 2 miRNAs as competing endogenous RNAs (ceRNAs). In summary, our study demonstrated the dysregulated lncRNAs/miRNAs, particularly LINC00925/miR-9 and MIR155HG/miR-155, regulate the development of cervical cancer by forming a interaction network with mRNAs, highlighting the importance of elucidating the underlying mechanisms of ncRNAs in cervical cancer development.
Evaluation of the Efficacy and Toxicity of Radiotherapy for Type III-IV Portal Vein Tumor Thrombi
Authors: Bai Shuheng , Wu YinYing , Yan Yanli , Li Rong , Kang Haojing , Zhang Jiangzhou , Ma Wen , Gao Ying , Hui Beina , Ma Hailin , Zhang Xiaozhi , Ren Juan
Published: February 2021

Background:

Type Ⅲ and Ⅳ portal vein tumor thrombi (PVTT) cannot be removed through surgery, and no effective therapeutic procedure is available. Type Ⅲ/Ⅳ PVTT can be downstage to type I/II PVTT by using Radiotherapy, and can further be can be removed surgically. Thus, radiotherapy may be an effective treatment for type Ⅲ/Ⅳ PVTT. This study aims to evaluate the efficacy and toxicity of radiotherapy for type III-IV PVTT.

Methods:

This prospective study was conducted from August 1, 2017, to September 30, 2019, for patients with type Ⅲ and Ⅳ PVTT. Patients received radiotherapy with a target dose of 50Gy/25f or 59.5Gy/17 f. Advanced radiological technique such as image fusion technique for CT image and MRI image were utilized to produce more precise lesion localization, and limit the dose to organs at risk in order to get a better downstage rate and less adverse complications.

Results:

Nine (9) patients with type Ⅲ PVTT and 5 patients with type Ⅳ PVTT were included in this study. 12 patients received a radiotherapy dose of 50Gy/25f, 2 patients received 59.50Gy/17 f. After radiotherapy, 92.9% of patients with PVTT were successfully downstage to type II/I. In patients with primary hepatocellular carcinoma, 8 patients (accounting 88.9%) achieved down-stage. 5 patients with other types of tumors achieved downstage which accounts 100%. In addition, none of the 14 patients observed radiation hepatitis and radiation liver failure. And none of the patients developed gastrointestinal ulcers and thrombocytopenia.

Conclusion:

Radiotherapy is a suitable treatment measure for type Ⅲ and Ⅳ PVTT to get downstage and make the opportunity for surgery. Image fusion technology for precise lesion location such as CT-MRI image fusion, and strict dose limitation of organ at risk, contributed to the improvement of radiotherapy efficiency and the significant decrease in adverse complications.
Dysregulation of brain dopamine systems in major depressive disorder
Authors: Delva Nella C , Stanwood Gregg D
Published: February 2021

Major depressive disorder (MDD or depression) is a debilitating neuropsychiatric syndrome with genetic, epigenetic, and environmental contributions. Depression is one of the largest contributors to chronic disease burden; it affects more than one in six individuals in the United States. A wide array of cellular and molecular modifications distributed across a variety of neuronal processes and circuits underlie the pathophysiology of depression—no established mechanism can explain all aspects of the disease. MDD suffers from a vast treatment gap worldwide, and large numbers of individuals who require treatment do not receive adequate care. This mini-review focuses on dysregulation of brain dopamine (DA) systems in the pathophysiology of MDD and describing new cellular targets for potential medication development focused on DA-modulated micro-circuits. We also explore how neurodevelopmental factors may modify risk for later emergence of MDD, possibly through dopaminergic substrates in the brain.
WISP1 aggravates cell metastatic potential by abrogating TGF-β-Smad2/3-dependent epithelial-to-mesenchymal transition in laryngeal squamous cell carcinoma
Authors: Song Dandan , Wang Liang , Su Ke , Wu Huanhuan , Li Junli
Published: February 2021

Laryngeal squamous cell cancer (LSCC) is a common carcinoma with high morbidity and mortality. Metastasis constitutes the major cause of death and poor prognosis among patients with LSCC. Recent evidence confirms critical function of Wnt1-inducible signaling protein 1 (WISP1) in several cancers. However, its contribution in LSCC metastasis remains unclear. Specimens of tumor tissues and adjacent normal mucosa were collected from patients with LSCC. The mRNA and protein levels were determined using quantitative real-time PCR and Western blot, respectively. RNA interference was applied to silence the expression of WISP1 and TGF-β, and recombinant adenovirus was used to overexpress WISP1 in human LSCC cell line TU212 cells. Cell invasion and migration were determined by transwell assay. High expression of WISP1 was observed in LSCC tissues, especially in those from metastatic groups. Ectopic expression of WISP1 enhanced invasion and migration of TU212 cells. On the contrary, WISP1 knockdown reduced numbers of invasive and migrated cells. Additionally, elevation of WISP1 depressed the expression of epithelial marker E-cadherin and increased levels of mesenchymal marker vimentin in TU212 cells, whereas WISP suppression yielded the opposite effects. Further analysis corroborated that WISP1 overexpression enhanced activation of TGF-β-Smad signaling by increasing expression of TGF-β1, p-Smad2, and p-Smad3, which was abrogated following WISP1 down-regulation. Moreover, TGF-β1 exposure facilitated LSCC cell invasion and migration. Notably, blockage of the TGF-β-Smad pathway by si-TGF-β overturned WISP-1-evoked epithelial-to-mesenchymal transition (EMT), and subsequent cell invasion and migration. These findings highlight the pro-metastatic function of WISP1 in LSCC by regulating cell invasion and migration via TGF-β-Smad-mediated EMT, supporting a promising invention target for LSCC therapy.
Racial/Ethnic Segregation and Urban Inequality in Kansas City, Missouri: A Divided City
Authors: González-Pérez Jesús M.
Published: February 2021

Racial/ethnic segregation is a cause of urban inequality. This, in turn, perpetuates disadvantaged groups’ spatial segregation and difficulty in upward mobility. Planned racial and social segregation through a process of redlining almost one hundred years ago is fundamental to understanding today’s patterns of urban inequality. The aim of this study is to analyze the links between racial/ethnic segregation and inequality in Kansas City (MO). After studying the origins and significance of redlining in the city, an analysis is made of the distribution and segregation of the African American and Hispanic populations at an intra-urban level in addition to an analysis of urban inequality at a census tract level, using economic and housing indicators. We conclude that Kansas City is a divided city. The processes of segregation and inequality are clearly interrelated. The historical redlining map of racial segregation is reflected in today’s socio-spatial map of inequality.
Contemporary Endovascular 30-Day Outcomes for Critical Limb Threatening Ischemia Relative to Surgical Bypass Grafting
Authors: Latz Christopher Alan , Boitano Laura , Wang Linda J. , Pendleton Anna A. , DeCarlo Charles , Sumpio Brandon , Schwartz Samuel , Srivastava Sunita , Dua Anahita
Published: February 2021

Objectives:

Data from 2011-2014 showed lower extremity bypass(LEB) outperforming infrainguinal endovascular intervention(IEI) regarding major adverse limb events(MALE) but noted no significant difference in major adverse cardiac events(MACE) in propensity matched cohorts. This study aimed to determine if more recent(2015-2018) endovascular outcomes data have improved relative to surgical bypass.

Methods:

Patients who underwent intervention for chronic limb threatening ischemia (CLTI) from 2015-2018 were identified using the American College of Surgeons National Quality Improvement Program(NSQIP) Vascular Surgery module. The cohort was categorized as undergoing lower extremity bypass(LEB) or infrainguinal endovascular intervention(IEI). Primary 30-day outcomes included major adverse cardiac events(MACE), major adverse limb events(MALE), and major amputation. Inverse probability weighting was used for multivariable analysis.

Results:

A total of 10,783 patients underwent an infrainguinal intervention for CLTI from 2015-2018. Of these, 6,003(55.7%) underwent LEB and 4,780(44.3%) underwent IEI. Forty percent of the cohort was considered “high anatomic risk” by Objective Performance Goals(OPG) standards, and 13.6% were considered “high clinical risk.” The IEI cohort vs. the LEB cohort experienced a Myocardial infarction(MI)/Stroke rate of 1.8% vs. 3.6%(p < .001), and had a mortality rate of 2.0% vs. 1.7%(p = .22), which yielded a composite MACE of 3.4% vs. 4.8%(p = .001). The rate of reintervention for IEI vs LEB was 4.4% vs. 5.3%(p = .04), the loss of patency (without re-intervention) rate was 1.8% vs. 1.8%(p = 1.0), and the major amputation rate was 4.1% vs. 3.5%(p = .15), which resulted in a MALE rate of 9.1% vs. 8.8%(p = .50). Following inverse probability weighting, comparing the IEI to the referent LEB, MALE AOR = 1.17, 95% CI[1.01 -1.36], p = .036, MACE AOR = 0.61, 95% CI[0.49-0.74], p < .001, and major amputation AOR = 1.31, 95% CI[1.05 -1.62], p = .016.

Conclusion:

Endovascular outcomes continue to demonstrate inferiority in major amputation and overall MALE. However, endovascular intervention has a significantly reduced incidence of MACE. Overall, these results demonstrate an improvement in endovascular MACE rates in recent years relative to surgical bypass.
Effects of a Literacy Feature in an Augmentative and Alternative Communication App on Single-Word Reading of Individuals with Severe Autism Spectrum Disorders
Authors: Caron Jessica , Light Janice , McNaughton David
Published: February 2021

The purpose of this study was to investigate the effects of an augmentative and alternative communication (AAC) app with transition to literacy (T2L) software features (i.e., dynamic text and speech output upon selection of a graphic symbol within the grid display) on the acquisition of 12 personally relevant single words for individuals with severe autism spectrum disorder (ASD) who had minimal or no speech. The study implemented a single-subject, multiple-probe, across word sets design with four participants. All four participants in this study demonstrated increased accuracy reading targeted single words and results from this study provide preliminary evidence that the T2L features can positively affect the single-word learning of individuals with ASD who have minimal speech and limited literacy skills.