bluuebunny/crossref_metadata_2025 huggingface dataset:
Studi Mikrotremor dengan Metode Horizontal to Vertical Spectral Ratio (HVSR) di Tapak RDE, Serpong
Authors: Iswanto Eko Rudi , Indrawati Yuni , Riyanto Theo Alvin
Published: June 2020

ABSTRAKBencana alam seperti kejadian gempa bumi dapat menyebabkan kerusakan pada area tapak dan infrastruktur termasuk fasilitas reaktor nuklir. Fenomena ini perlu dipahami secara komprehensif melalui catatan sejarah karakteristik dinamik tapak. Penggunaan mikrotremor dengan metode Horizontal to Vertical Spectral Ratio (HVSR) telah digunakan secara luas dalam investigasi bawah permukaan sejak satu dekade terakhir. Tujuan penelitian ini adalah mengetahui karakteristik geologi setempat dan karakteristik dinamis bawah permukaan. Penelitian ini mengaplikasikan penggunaan mikrotremor metode HVSR di tapak Reaktor Daya Eksperimental (RDE) di Serpong. Pengukuran dilakukan di 15 lokasi, kemudian data diolah dengan metode HVSR menggunakan perangkat lunak Geopsy. Hasil analisis menunjukkan bahwa Tapak RDE mempunyai nilai frekuensi dominan antara 3,06 Hz–23,27 Hz dan faktor amplifikasi 1,84–6,37. Bagian timur laut dan tenggara tapak memiliki indeks kerentanan seismik yang lebih tinggi dibandingkan dengan bagian lainnya. Oleh karena itu, pilihan lokasi gedung reaktor di area barat daya sudah tepat kerena memiliki faktor amplifikasi, ketebalan sedimen, dan indeks kerentanan seismik yang relatif rendah.ABSTRACTNatural disaster like earthquake can cause damage to the site and the infrastructure including nuclear reactor facilities. This phenomenon needs comprehensively understood through its dynamic characteristics historical records of the site. The use of Horizontal to Vertical Spectral Ratio (HVSR) method has been widely used for subsurface investigation since last decade. The aimed of the research is to obtain local geological and subsurface dynamic characetristics. This research is applying the use of HVSR method for Experimental Power Reactor (RDE) in Serpong. The measurements are in 15 locations, and then the data is processed by using Geopsy software. The analysis result shows that the RDE site has dominant frequncy values between 3.06 Hz–23.271 Hz and amplification factor 1.84–6.37. The northeast and southeast areas of the site have higher seismic vulnerability index than in other area. Therefore, the selection for reactor bulding location in the southwest area is proper because it has lower amplification factor, sedimen thickness, and seismic vulnerability index.
Penentuan Daerah Prospek Logam Tanah Jarang di Pulau Singkep
Authors: Ngadenin Ngadenin , Karunianto Adhika Junara , Indrastomo Frederikus Dian
Published: June 2020

ABSTRAK Logam tanah jarang merupakan bahan stategis yang digunakan pada perangkat teknologi tinggi dan energi bersih. Di Indonesia logam tanah jarang terkandung dalam mineral monasit, zirkon, dan xenotim sebagai mineral-mineral ikutan pada penambangan timah di zona granit jalur timah Kepulauan Riau hingga Bangka Belitung. Singkep merupakan salah satu wilayah potensial logam tanah jarang karena terletak pada zona granit jalur timah. Penelitian ini bertujuan untuk menentukan daerah prospek logam tanah jarang di Pulau Singkep. Metoda yang digunakan adalah pengambilan 25 sampel konsentrat dulang pada beberapa tailing bekas tambang timah di Pulau Singkep. Sampel diambil pada setiap formasi batuan yang ada di Pulau Singkep dari batuan berumur tua hingga batuan berumur muda berturut-turut adalah kuarsit Bukit Duabelas berumur Permo-Karbon, komplek malihan Persing berumur Permo-Karbon, granit Muncung berumur Trias, granit Tanjungbuku berumur Yura, endapan rawa dan aluvium berumur Holosen. Setiap sampel konsentrat dulang dibagi menjadi dua bagian untuk analisis kandungan logam tanah jarang dan analisis mineral butir. Dua puluh lima (25) sampel dianalisis kandungan logam tanah jarangnya dan 14 sampel dianalisis kandungan mineral butirnya. Hasil analisis kandungan logam tanah jarang dan mineral butir menunjukkan bahwa daerah prospek logam tanah jarang terletak pada beberapa tailing bekas tambang timah di wilayah formasi batuan granit Muncung. Kadar lanthanum tertinggi mencapai 20100 ppm, cerium 37100 ppm, yttrium 9872 ppm dan neodymium 2840 ppm di mineral monasit, zirkon dan alanit.ABSTRACT Rare earth elements (REE) are strategic material used in high-tech and clean energy devices. In Indonesia, REE contained in monazite, zircon, and xenotime minerals as accessories minerals in tin mining located in the granite tin belt of Riau Islands to Bangka Belitung. Singkep is one of the potential areas of REE because its location is in the granite tin belt. The goal of the study is to determine the REE prospects in Singkep Island. The method used by taking 25 pan concentrated samples on some tailing ex tin mining on the Singkep island. These samples were taken from each rock formation on Singkep Island in sequence from older to younger rocks formation, respectively. They are Permian Carboniferous of Bukit Duabelas quartzites, Permian Carboniferous of Persing Metamorphic Rocks, Triassic Muncung granite, Jurassic Tanjungbuku granite, Holocene swamps deposits and alluvium. Each sample of pan concentrated is divided into two parts for REE content and grain mineral analysis. All 25 samples were analyzed for REE content, while only 14 samples for the grain mineral. The results of REE content and grain mineral analysis indicate that the REE prospect area located in the tailings ex tin mining in the rock formation of the Muncung granite area. The highest concentration of lanthanum reached 20100 ppm, cerium 37100 ppm, yttrium 9872 ppm, and neodymium 2840 ppm in monazite, zircon, and allanite.
ANALYSIS ON THE PERFORMANCE OF THE BANDUNG CONVERSION FUEL-PLATE TRIGA REACTOR IN STEADY STATE WITH CONSTANT COOLANT FLOW RATE
Authors: Hastuti Endiah Puji , Alfa Sudjatmi K. , Sudarmono Sudarmono
Published: June 2020

Bandung TRIGA2000 Reactor, a General Atomic (GA)-made research reactor used for training, research andiIsotope production, has been upgraded to operate at power of 2000 kW using TRIGA fuel rod type. Recently, the TRIGA reactor fuel element producers are going to discontinue the production of TRIGA fuel element. To overcome the unavailability of TRIGA fuel element, BATAN planned to modify TRIGA2000 fuel type from rod-type to U3Si2-Al plate-type fuel with 19.75% enrichment, similar to the domestically fabricated one used in RSG-GAS. The carried out design emphasized on the determination of operation condition limits for setting the reactor protection system in accordance to the reactor safety calculation results. The conceptual design of the innovative fuel plate TRIGA reactor cooling system is expected to remove heat generated by fuels with nominal power of 1 MW up to 2 MW. The design is developed through modelling and safety analysis using COOLOD-N2 validated code. The safety margin is set to its flow instability at transient condition of the fuel plate, which is ≥ 2.38; departure from nucleate boiling ratio ≥1.50; and no onset of nucleate boiling, ΔTONB ≥ 0oC. The primary coolant flow rate accommodating the existing Bandung TRIGA reactor capability is as high as 50 kg/s. The analysis results show that at power of 1 MW, the reactor can safely operate, while at power of 2 MW the safety margin is exceeded. In other words, the plate TRIGA reactor that employs forced convection mode operates safely at 1 MW with excess power 120% of its nominal power.Keywords: 1 MW, Thermalhydraulic design, Steady state condition, TRIGA plate, Constant flowrate
Gel Slice Sample Preparation for Proteomics v1
Authors: Gin Jennifer , Chan Leanne , J Petzold Christopher
Published: June 2020

This protocol details steps for gel slice sample preparation for proteomic data acquisition. It was adapted from Shevchenko et al. "In-gel digestion for mass spectrometric characterization of proteins and proteomes."Nature protocols 1.6 (2006): 2856.
A distribution-dependent analysis of open-field test movies v1
Authors: Konishi Tomokazu
Published: June 2020

Although the open-field test has been widely used, its reliability and compatibility are frequently questioned. Many indicating parameters were introduced for this test; however, they did not take data distributions into consideration. This oversight may have caused the problems mentioned above. Here, an exploratory approach for the analysis of video records of tests of elderly mice was taken that described the distributions using the least number of parameters. The locomotor activity of the animals was separated into two clusters: dash and search. The accelerations found in each of the clusters were distributed normally. The speed and the duration of the clusters exhibited an exponential distribution. Although the exponential model includes a single parameter, an additional parameter that indicated instability of the behaviour was required in many cases for fitting to the data. As this instability parameter exhibited an inverse correlation with speed, the function of the brain that maintained stability would be required for a better performance. According to the distributions, the travel distance, which has been regarded as an important indicator, was not a robust estimator of the animals’ condition.
SOCIO-GEOGRAPHICAL ANALYSIS OF FUNCTIONING TOURIST-REGIONAL COMPLEX IN KHMELNYTSKYI REGION
Authors: Dolynska Olesya Olehivna
Published: June 2020

The aim of the study is a socio-geographical analysis of the development opportunities of the Khmelnitsky region regional tourist complex; study of social and geographical essence of regional tourist complexes and functioning of Khmelnitsky region tourist-regional complex in the context of Khmelnitsky region territorial organization and complex-proportional development and Ukrainian economy.

Methods. The study uses general scientific and special methods of geographical science, namely: formal logic and systematization; mathematical and statistical; comparative geographical analysis; grouping, typing and zoning, cartography. The information base of the research consists of materials of the State statistics service of Ukraine and the Main Department in Khmelnitsky region, as well as abstracts and scientific publications in professional publications. A part of the information is taken from the official plans, strategies and other regulatory documents for the Khmelnytsky region tourism activities development and its administrative-territorial units.

Results. The spatial regularities of the Khmelnitsky regional tourist complex are characterized and formulated. Modern problems of development of tourist complex of Khmelnitsky region are investigated; features of a modern state of development of tourist complex of Khmelnitsky region are revealed and disclosed. Theoretical generalizations of the regional tourist complex research of the semi-peripheral region of Ukraine can be used in carrying out the corresponding scientific researches of other similar regions, management of the regional tourist complex in the conditions of social transformations.

Scientific novelty. Promising directions of the Khmelnitsky region regional tourist complex development received further development. The socio-geographical study approaches of the regional tourist complex have been improved. The factors analysis of Khmelnitsky tourist-regional complex functioning is carried out. The component, territorial and administrative aspects of the functional structure of the tourist-regional complex of Khmelnitsky region are analyzed on the basis of the structural analysis.

Practical significance. The results of the research can be used: for strategic planning of economic and social regional development of semi-peripheral Ukrainian regions; in the development of measures to enhance and improve regional tourist complexes; in determining the priorities for the development of newly United territorial communities; for regional planning and forecasting activities, including the image and attractiveness of new tourist facilities. The obtained scientific results are used in the educational process of future specialists in the field of training "Tourism", with the educational qualification "Tourist expert, organizer of excursion and animation activities" in the teaching of disciplines "Local history and tourism", "Tourist work", "Recreational geography".
ORIENTEERING AS A COMPONENT OF THE RECREATIONAL TOURISTIC POTENTIAL IN KIROVOGRAD REGION
Authors: Zarubina Antonina Volodymyrivna , Shcherbatiuk Nataliya Ivanivna
Published: June 2020

Article purpose: in this article orienteering is considered as a component of sport tourism, main historical development features of this kind of sport within Kirovograd region are detected, modern development trends are analyzed and its meaning for forming of the recreational touristic potential in Kirovograd region is determined.

Methodology: theoretical generalization is made as for the special features of this kind of sport, scholarly and scientific work concerning the tourism development perspectives in Kirovograd region are analyzed and the recreational touristic potential is evaluated. Special features and meaning of sport mapping to popularize tourism and orienteering in particular in the region are indicated.

Results: it has been determined that today orienteering as a sport tourism component is a very popular direction which has acquired some modern development tendencies. This direction of tourism not only shapes sports skills that aim to get a certain result, but also defines the features of healthy, active rest for a wide range of society, forms vital skills to navigate unfamiliar terrain. Peculiarities of the existing sport maps for competition holding and for recreational touristic activities were analyzed and also the proposed territories those which could be interesting for future usage. As a rule, competitions are interesting both in natural and cultural-historical terms of the territory.This encourages the revitalization of the local lore and tourism research in their region. Almost all sports orientation maps have nature reserves and territories of different categories. New development directions of orienteering were defined having the matter to popularize this kind of sport, namely active development of city and park orientation with use of typical urban area are noted. This contributes to the promotion of sports orientation and makes it more accessible to all concerned. The experience of such competitions is being studied in the cities of Odessa, Kiev, Lviv, Kamianets-Podilskyi, etc. for the realization of this direction.

Scientific novelty. It is the first occurrence when orienteering has been viewed as a component of the recreational touristic region potential that has a strong value for health-relating, regional ethnographical and other types of recreational touristic activities devoted to different age groups present in the society.

Practical value. The results of the performed studies are being used in the educational activity carried out at the Physical Education and Natural Geographic Departments, also they are being used by regional tourism ethnography and travelling center to conduct the class lessons and to hold competitions.
Use of echocardiographic parameters of longitudinal mechanics to estimate diastolic function of systemic ventricle in patients after fontan operation
Authors: Sinelnikov Yu. S. , Matanovskaya T. V. , Orekhov S. A.
Published: June 2020

Objective. To study the possibilities of using echocardiographic parameters of longitudinal mechanics to assess the diastolic function of the systemic ventricle (SV) in patients after Fontan operation.

Material and methods. We examined 29 children aged 8,6 3,16 years with a functionally single ventricle of the heart after performing a total cavopulmonary connection with fenestration of extracardiac conduit. By computed tomography there were evaluated: myocardial mass index (MMI) SV, ejection fraction (EF) SV, cardiac output (CO) SV, cardiac index (CI) SV. In addition to conventional echocardiographic (Echo) parameters, we also studied: diastolic velocity parameters of the longitudinal mechanics of the SV during the early rapid filling phase (SR E), in the phase of late diastolic filling (SR A), the ratio of the peaks of the strain rate (SR E/SR A), the stiffness index of a functionally single atrium, the atrial strain in conduit phase (AS cd), reservoir (ASr), and in the contractile phase (AS ct).

Results. Reduced values of the SI, CO and CI SV, an increase in MMI SV, normal values of EF SV. The parameters of the longitudinal diastolic strain rate in the early and late filling phases of e SV showed a direct significant correlation with SI, CO and CI SV and inverse correlation with E/e '. Parameters of longitudinal strain of the functionally single atrium in all phases were reduced, they all correlated with E / e, SR E / SR A, MMI SV, SI, CO and CI SV. There was no statistically significant relationship between the parameters of the longitudinal function of the atrium in all phases and atrial stiffness with sex and body surface area.

Conclusions. 1. The parameters of the longitudinal diastolic strain rate can be used to identify the diastolic dysfunction of the systemic ventricle in children after Fontan operation. 2. The hemodynamic parameters of the systemic ventricle (stroke index, cardiac output, cardiac index) determine the parameters of its diastolic mechanics. 3. The reservoir, conduit, and contractile atrial function in patients after total cavopulmonary connection are associated with both characteristics of diastolic longitudinal strain rate and hemodynamic parameters of systemic ventricle.
Seismic History of Central North Anatolian Region: New Contribution from Ottoman Archives
Authors: Şeşetyan Karin , Sakin Orhan , Sönmez Serpil , Demircioğlu Tümsa Mine Betül
Published: June 2020

Contemporary Ottoman sources bring a major contribution to the description of the seismic activity in the eastern Mediterranean region and are extensively used by historical seismologists. Among these, the documents of the Ottoman State Archives (Istanbul), and more specifically the correspondence of the local governors with the central authorities form a valuable source for the description of the earthquake effects in territories, which were under the Ottoman rule. Especially for the more recent periods, we observe that not only major earthquakes but also small-to-moderate-size events with local effects find their place in these documents. However, due to the complex and insufficiently categorized structure of the archival material, as well as the need for expertize in Ottoman language and history, except the sections covered in the works of N. Ambraseys and C. Finkel and a number of earthquake-specific studies, these documents are not yet fully exploited in the definition of the regional seismic history.

In this pilot study, we investigate the Ottoman archive material related to earthquake effects in the central North Anatolian region and search for possible supportive or new contribution to the seismic history of the study area. The period of investigation is the nineteenth century, with occasional data also found for the pre and postperiod. The study revealed supportive information for 15 earthquakes that were already known to previous compilations, and data for 19 earthquakes that we categorize as new events, demonstrating the value of this primary source and the wealth of macroseismic information that can still be extracted, revealing earthquakes so far unknown as well as enriching the descriptive information related to already known ones.
Pemanfaatan Lactobacillus plantarum 1 dan Pewarna Alami Berbahan Nabati Dalam Pembuatan Tapai Probiotik
Authors: Yusmarini Yusmarini , Fitriani Shanti , Johan Vonny Setiaries , Rahmayuni Rahmayuni , Artanti Vita F.
Published: June 2020

Tapai is one of the typical Indonesian fermented products. This research utilized Lactobacillus plantarum 1 RN2-53 and natural dyes made from plants in the production of cassava tapai. The objectives of this research were to improve the quality of probiotic cassava tapai and to obtain the chemical, microbiological and sensory characteristics of the cassava tapai. Natural dyes used were purple sweet potato extract, red dragon fruit extract and narrow-leaf pleomele extract. The results showed that cassava tapai made with the addition of Lactobacillus plantarum 1 RN2-53 and the addition of natural dyes from plants had different chemical and microbiological characteristics. Tapai made with the addition of red dragon fruit extract generally had a lower pH value and a higher total titrated acid compared to tapai made with the addition of purple sweet potato extract and narrow-leaf pleomele extract, but the alcohol content of tapai made with the addition of purple sweet potatoes extract was higher than the others. The number of lactic acid bacteria was around 109 and had met the probiotic food criteria.
Assessment of Some Wetland Potentials in Makurdi Supporting Rice and Sugarcane Production
Authors: Usman Jacob , Ogbu J.O. , Iji S.E. , Afatar S.
Published: June 2020

The study was carried out in Makurdi, Benue State with the view to characterize some wetlands of Makurdi area and their suitability to rice and sugarcane production. In order to characterize and classify the soil, four pedons were dug at the selected seasonally flooded wetlands. The soils were characterized in terms of their morphological, physical and chemical properties. The soils were generally sandy loam, loamy sands and sandy clay loam. The distribution of clay content increased with soil depth for all pedons. The soils were strongly to moderately acid in reaction (3.47 to 5.61) in H2O. The soils had low (0.2 to 3.77 g/kg) organic carbon. The percentage base saturation ranged from 5 to 75 %. The soils were classified as Vertic Endoaquepts/Vertic Gleysols (Orthoeutric), Aeric Glossaqualfs/Lixic Gleysols (Orthoeutric) and Typic Epiaquults/Ferralic Acrisols (Epidystric). Soil Type B was marginally suitable (S3) for sugarcane. However, all the 4 soil types were moderately suitable (S2) for rice.
Evaluation of Harvesting and Seed Dormancy Overcoming Techniques in Hymenaea courbaril Germination
Authors: Regnier Leonardo
Published: June 2020

Hymenaea courbaril is an endangered Brazilian native species. Recently, this species has been used on reforestation programs. So, production techniques that propitiate faster germination are very important. Although, seed dormancy, which could hamper the seedling production process, is not extensively recognized. Thus, this study focused on evaluating the influence of early harvest technique, scarification and pre-imbibition techniques to overcome H. courbaril seed dormancy in two steps. First, evaluating green fruits harvest could influence the germination process, 137 visually healthy seeds from green fruits and 400 seeds from mature fruits were selected. Seeds from green fruits presented similar results to seeds from mature fruits. Probably due to the natural seed tegument rupture. After, the influence of mechanical scarification, pre-imbibition and the combination of both methods were measured. All studied processing methods did not affect significantly any of the germination measurement parameters. Mechanical scarification exhibits similar responses as previous studies showed when using acid scarification. The technique of harvesting green fruits from the treetop seems to be applicable to commercial seedling production. While none of the studied treatments promoted significantly benefits to germination at any of the indexes.
Rayleigh Wave Analysis in the Presence of High Impedance Boundaries
Authors: Gribler Gabriel
Published: June 2020

Surface wave data is commonly used to estimate shear wave velocity of the subsurface.
Most standard approaches for analyzing surface wave data fail under conditions when
high-impedance boundaries, or sharp contrasts, exists within the range of sensitivities.
I present two primary scenarios, one with a high velocity bedrock layer in the upper 20
meters overlain by low velocity unconsolidated sediment, and a thin high velocity road
layer on top of unconsolidated sediments. For the shallow bedrock case, I present new
multicomponent methods to more accurately and reliably extract surface wave dispersion
information from active source waveforms. I also present a new data inversion method that
utilizes additional information from multicomponent wavefields, allowing for more accurate
estimates of shear wave velocities in these environments. For the thin, high velocity surface
layer, I highlight the potential pitfalls of ignoring this layer when inverting for the
underlying shear wave velocities, and I propose a solution that yields more accurate velocity
estimates. All of these approaches are explained and presented using modeled data, then
extended to highlight the improvements over standard approaches using real data.
Value and moral component of the concept «future» in Russian linguoculture
Authors: Stolyarova Alexandra G.
Published: June 2020

The paper deals with culture generating texts treated as speech products corresponding to dominant features of civilization in cultural history. Three types of such texts - sacral regulations, mass circulation products and virtual net messages - have radically changed the idea of authorship and corresponding attitudes of public to texts. The first text type brought to life selected priests who were regarded as keepers of sacral knowledge to be transmitted to coming generations, the second text type initiated numerous artisans who produced various one-time texts suitable for everyday purposes, the third text type generated illusionists who launch secondary texts through the world electronic network for the sake of carnival play with life. The characteristics of three types of text as indicators of culture have been described on the material of aphorisms. Autosemantic sentences of the first type are usually expressed as manifestations of general truth or common norms of behavior, the second type phrases function as trivial observations or specific recommendations in particular situations, whereas the third type texts have a paradoxical nature or are used as banter expressions uttered to fill the gaps in conversation. Sentences of the first type make the core golden reserve of human wisdom, and they are often used in situations of social inequality when people demonstrate their experience and right to give lessons to others. Sentences of the second type are very important for everyday routine life, and they appear in corresponding habitual situations. Sentences of the third type are applied mainly in interactions which require a critical reaction to any type of edification, either moral or utilitarian, their aim is to establish equality as such by means of ridicule of any kind of self-admiration.
Edición genómica heredable: un estudio exploratorio desde la perspectiva del principio bioético de la beneficencia
Authors: Caro-Romero Henry David
Published: June 2020

Propósito/Contexto. Este artículo busca comprender el significado que tendría, para un grupo de personas residentes en Bogotá, la posibilidad de realizar variaciones genéticas, previas al nacimiento, en seres humanos. El estudio se centró en la aplicación de la técnica de alteración genómica CRISPR-Cas9, desde la perspectiva del principio bioético de la beneficencia, que está dirigido a realizar el mayor bien posible.Metodología/Enfoque. Primero, se efectuó una revisión teórica de la técnica CRISPR-Cas9 y del principio bioético de la beneficencia. Luego, se estudiaron documentos regulatorios internacionales acerca de la edición genómica. Con base en esto, se aplicó una encuesta, apoyada por un video, para conocer la decisión hipotética que tomaría un grupo de profesionales legos en temas bioéticos, frente a otro grupo de universitarios que recibieron formación bioética. Resultados/Hallazgos. Los resultados mostraron que la modificación genómica destinada a la prevención o a la terapia fue aprobada por ambos grupos, aunque con diferencias. La mejora genómica fue rechazada, en general, por considerarse inmoral; en ambos grupos se abrió la posibilidad de admitirla, no obstante, pero solo como preparación genómica para las futuras generaciones, debido a los efectos del cambio climático.Discusión/Conclusiones/Contribuciones. El principio bioético de la beneficencia resulta esclarecedor porque sugiere el bien, no solo individual sino común. Igualmente, se corrobora que existe una reserva moral frente a la edición genómica heredable.
Computational Modeling and Analysis to Predict Intracellular Parasite Epitope Characteristics Using Random Forest Technique
Authors: JAVADI Amir , KHAMESIPOUR Ali , MONAJEMI Farshid , GHAZISAEEDI Marjan
Published: June 2020

Background: In a new approach, computational methods are used to design and evaluate the vaccine. The aim of the current study was to develop a computational tool to predict epitope candidate vaccines to be tested in experimental models. Methods: This study was conducted in the School of Allied Medical Sciences, and Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Tehran, Iran in 2018. The random forest which is a classifier method was used to design computer-based tool to predict immunogenic peptides. Data was used to check the collected information from the IEDB, UniProt, and AAindex database. Overall, 1,264 collected data were used and divided into three parts; 70% of the data was used to train, 15% to validate and 15% to test the model. Five-fold cross-validation was used to find optimal hyper parameters of the model. Common performance metrics were used to evaluate the developed model. Results: Twenty seven features were identified as more important using RF predictor model and were used to predict the class of peptides. The RF model improves the performance of predictor model in comparison with the other predictor models (AUC±SE: 0.925±0.029). Using the developed RF model helps to identify the most likely epitopes for further experimental studies. Conclusion: The current developed random forest model is able to more accurately predict the immunogenic peptides of intracellular parasites.
Convalescent Plasma a Potential Therapy in Covid-19 Patients in Low Resource Setting: Rapid Review
Authors: Abdelmoneim Abdelrahman H. , Mustafa Mujahed I. , Abdalhaleem Adlan Raghda Hatim , Ahmed Abdulgader Noun Eltayeb , Osman Fadl Hiba Awadelkareem , Kamal Alhassan Nosaiba , G. Elbager Sahar
Published: June 2020

Background: The COVID-19 pandemic is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). At the time of writing, neither a cure nor a vaccine has been approved by the World health organization (WHO)  for this disease. Given the fact that the severe acute respiratory syndrome coronavirus  (SARS) and Middle East Respiratory Syndrome (MERS) viruses have a genetic sequencing similar to SARS-CoV-2, and since the use of convalescent plasma therapy (CP) has proved its efficacy in SARS and MERS virus infections, researchers are starting to focus more on it as a possible therapy for the COVID-19 disease. The main objective of this rapid review is to report and summarize the published evidence on the role of convalescent plasma therapy in the current COVID-19 pandemic.
Method: The PICO method was used to establish the review question. Moreover, papers were gathered from PubMed and Google scholar, critically appraised for the best evidence. Piersons 5-component scheme was used to check the quality of the review papers.
Results: After website screening: 10 papers in PubMed and 6 papers from Google scholars were retrieved. There were encouraging reports regarding the uses of CP in the previous viral outbreaks likes SARS and Ebola, yet there is still a doubt on the efficacy of this mode of therapy in the current COVID-19 pandemic.
Conclusion: CP is a very promising treatment approach for COVID-19 patients; however, more clinical trials are required to validate the effectiveness of this therapy.
Keywords: COVID-19, convalescent plasma therapy, SARS-CoV-2, therapy.
Niveles séricos de somatomamotrofina coriónica humana en embarazadas con hipertensión arterial. - Informe preliminar
Authors: Sánchez Torres Fernando , Reyes Leal Bernardo , Gómez Palacino Jesús A. , Bernal Hernández Eduardo
Published: June 2020

En 12 pacientes con embarazo mayor de 28 semanas y que presentaban hipertensión arterial por toxemia gravídica o de causa esencial, fueron estudiados mediante radioinmunoensayo los niveles séricos de somatomamotrofina coriónica (SCH).En 2 casos en que el feto falleció in útero la cifra de SCH estuvo por debajo de 4 ugr/ml. En otros 3 casos también con niveles bajos de la hormona, los fetos nacieron vivos pero con un puntaje de Apgar inferior a 5/10. En un caso con niveles menores de 4 ugr/ml. el feto nació en buenas condiciones.En los 6 casos restantes los niveles séricos de SCH fueron de 10 o más ugr/ml., habiendo nacido todos los fetos en óptimas condiciones según el puntaje de Apgar, a pesar de que 2 de ellos tenían malformaciones.
Editorial
Authors: De Obstetricia y Ginecología Federación Colombiana
Published: June 2020

La primera Revista científica colombiana que en publicación continua ha sobrepasado los 25 años es la nuestra.
Curva de Tolerancia a la Glucosa Reforzada con Triamcinolona en el Estado Grávido-Puerperal. Estudio Preliminar
Authors: Acosta Bendeck Eduardo , Vásquez Macías Néstor
Published: June 2020

Un grupo seleccionado de pacientes sospechosas de diabetes, se estudia mediante la curva de tolerancia a la glucosa reforzada con Triamcinolona, que aparece como un método eficiente paar el diagnostico temprano de la diabetes Mellitus.
IV Symposium Internacional sobre EPH - Gestosis
Authors: De Obstetricia y Ginecología Federación Colombiana
Published: June 2020

Alrededor de treinta países estuvieron representados, por cerca de seiscientos participantes. El éxito de las deliberaciones fue propiciado por la eficiencia y la dedicación de los organizadores, especialmente de los miembros de la Profesión Médica y del Cuerpo Científico y Docente de Israel, así como por la hospitalidad fraternal por ellos prodigada, lo que dio a este certamen un ambiente de cordialidad y de exaltación de los valores humanos en la investigación médica.
BACTRIM 'Roche' en el tratamiento de la gonorrea
Authors: De Obstetricia y Ginecología Federación Colombiana
Published: June 2020

BACTRIM 'Roche' fue uno de los tratamientos escogidos para ser aplicado a varios grupos de enfermos del sexo masculino, no seleccionados y que no habían sido tratados anteriormente, afectados de gonorrea uretral. Los tratamientos fueron asignados al azar a un total de 216 pacientes.
Editorial
Authors: De Obstetricia y Ginecologìa Federación Colombiana
Published: June 2020

El fin de año ha sido pródigo en honores para ALVARO VELASCO CHIRIBOGA, Ex-Director de nuestra Revista, quien ganara el Premio Nacional de Medicina Federico Lleras Acosta 1975 con su magnífico trabajo sobre la prevención de daño cerebral intraparto.
Tumores del ovario
Authors: Pérez Gómez Eduardo , Parada R. Carlos , Duarte Contreras Alberto , Luzardo M. Luis Fernando
Published: June 2020

Se hace un estudio de revisión de las neoplasias ováricas ocurridas en un lapso de 13 años en el Hospital San Juan de Dios, de Cúcuta. Se recopilaron 367 casos de los cuales 317 (86.9%) fueron benignos y 50 (13.1%) malignos. Las edades extremas oscilaron entre 3 y 90 años. Siguiendo la clasificación histogenética de Hertig y Gore, el tipo más frecuente de tumor fue el cistadenoma seroso, seguido de los quistes dermoides, cistadenocarcinoma y diversas clases de tumores. Se relievan la baja incidencia de tumores pseudomucinosos, la coexistencia de un cistadenocarcinoma papilar con un tumor de células granulosas, la asociación de un cistedon carcinoma seroso con embarazo y el hallazgo de un tumor de Brenner maligno. Se hace énfasis sobre el aumento de la incidencia del carcinoma ovárico, la baja tasa de supervivencia a los 5 años y la necesidad de medidas profilácticas para su detección temprana.
Esterilización femenina por laparoscopia en el período puerperal y de intervalo
Authors: Edelman David A. , Goldsmith Alfredo , Brenner William E.
Published: June 2020

Ya que las tasas de complicaciones especificas con esterilizaciones post-abotro y puerperales fueron bajas, estudios más amplios serán necesarios para evaluar adecuadamente estas tasas. Para determinar si hay un aumento en estas tasas de complicaciones especificas en pacientes esterilizadas después de aborto o en el puerperio, estudios que comparan las tasas de complicaciones de estos dos grupos con aquellos de pacientes no esterilizadas después de un aborto o parto normal deberán ser conducidos.
Esterilización femenina por minilaparotomía en pacientes ambulatorias: Una técnica modificada
Authors: Madrigal Vernon , Goldsmith Alfredo
Published: June 2020

En este reporte se describe una modificación en la técnica de minilaparotomía que hace posible la operación con un máximo de facilidad, un mínimo de instrumental y sin necesidad de ayudantes.
Arrenoblastoma
Authors: Moreno G. Armando , Guzmán Rúben Darío , Fonnegra M. Alvaro , Alvarado Pantoja Ricardo
Published: June 2020

El conocimiento de las características clínicas, la incidencia y comportamiento de este raro tumor ovárico, en nuestro medio está aún lejos de alcanzarse por la carencia de un sistema nacional de información y registro de tumores ováricos; motivación del médico para envío de las piezas quirúrgicas, para estudio anatomopatológico y carencia de recursos adecuados para envío, estudio y clasificación de las muestras, así como seguimiento de los casos.
"Bactrim" en infecciones genitales microbianas gonocócicas o no.
Authors: Siboulet A.
Published: June 2020

En vista de la sorprendente recrudescencia que en muchos países han adquirido las infecciones urogenitales transmisibles, el autor estudió la acción del Bactrim Roche en varias de ellas
Tumores funcionales del ovario
Authors: Guzmán A. Rubén Darío , Fonnegra M. Alvaro , Alvarado P. Ricardo , Moreno Armando
Published: June 2020

Se presentan 12 casos de tumores de la granulosa, teca-granulosa y te-comas manejados en 15 años.La edad de aparición entre 24 y 70 años; no se les diagnosticó pre-operatoriamente; generalmente unilaterales. Se revisan las diferentes teorías etiológicas; se comentan su Histología, su clínica y su tratamiento.
"Embarazo abdominal con feto vivo a término"
Authors: Acosta Bendek Eduardo
Published: June 2020

La publicación tardía del presente caso ha sido deliberadamente aplazada con el objeto de haber continuad o en seguimiento de la niña; hasta el presente en su desarrollo psicofísico no ha presentado ninguna alteración.
Mortalidad perinatal en Instituciones hospitalarias de Bogotá
Authors: Rodríguez Soto Arturo , Macías Marcelino , Amaris Mora Alberto , Castillo Jóse David , Pedraza Gaitán Jaime , Cárdenas Hebert Wargner , Ruiz Acevedo Jaime Enrique , Gutiérrez Enrique , Roa Juan , Paéz Vargas Roberto , Heredia Reinaldo
Published: June 2020

Se presenta un estudio de mortalidad perinatal intrahospitalaria en cuatro instituciones de la ciudad de Bogotá , las cuales representan diferentes grupos humanos con condiciones socioeconómicas y culturales di- versas.
Lípidos totales en el liquido amniótico
Authors: Cortés Caballero Carlos , Motta T. David , Caballero de la Rans Olga
Published: June 2020

El interés en los cambios séricos de los lípidos en condiciones fisiológicas y con medicación (1) nos apartó un poco de las mediciones usuales hechas en líquidos amnióticos (5) con el animo de relacionarlas en la edad progestacional (8) o estados de toxemia (6,7) y nos llevó a practicar determinaciones de lípidos totales con el fin de hacer algún aporte al establecimiento de valores normales en nuestro medio.
Cáncer de cérvix uterino y cesárea a repetición
Authors: Bueno M. Miguel , Guzmán Nelly
Published: June 2020

El Cáncer del Cérvix Uterino es el tumor maligno más frecuente en nuestro medio. En Colombia, al igual que en otros países del mundo, representa una causa importante de mortalidad.
Cirugía del prolapso genital
Authors: Henao Arango Fabio , Restrepo Ramírez Hernán , Amorocho Pedraza Néstro
Published: June 2020

Entre las Entidades Ginecológicas que requieren tratamiento quirúrgico, la más frecuente en nuestro medio, es el Prolapso Genital.
Bactrim 'Roche' en el tratamiento de la cistitis
Authors: González Arizabaleta Danilo
Published: June 2020

Fueron tratadas 20 pacientes pertenecientes al sexo femenino con Cistitis comprobada por medios clínicos, para-clínicos y bajo visión directa por medio de la endoscopia urológica.Se utilizó un nuevo producto compuesto por la asociación de 80 mg de Trimetoprim y 400 mg de Sulfametoxazol (BACTRIM 'Roche'), suministrado por vía oral y en las dosis de dos tabletas tres veces al día por una semana. Los resultados fueron satisfactorios en el 95% de los casos, considerándose a los pacientes curados al fin del tratamiento.Las pacientes fueron seleccionadas descartándose cualquier origen obstructivo.
Carcinoma de cuello uterino revisión y manejo
Authors: Rengifo Pardo Jaime
Published: June 2020

Este trabajo no muestra nada nuevo, pero significa el estudio y revisión de los casos de carcinoma del cuello uterino en los dos primeros años de funcionamiento del Hospital Regional Federico Lleras de Ibagué.
Morfología de la Placenta
Authors: Cortés C Carlos , Gamboa G. Alvaro , García G. Gonzalo , Mutis M. Mario
Published: June 2020

La dificultad técnica en el anáisis cuantitativo (7) y lo poco accesible de algunos métodos como la microscopia de fase (9), en los hallazgos placentarios, han hecho que se dé poca importancia a su estudio morfológico; no obstante que se le atribuye hasta un 40% como causa de muerte intrauterina y prenatal (5). Si a esto se agrega que la literatura no proporciona información precisa sobre parámetros de normalidad y anormalidad y en ambas condiciones ocurren alteraciones degenerativas, sin delimitarlas para poder apreciar la diferencia; se ve la necesidad de trabajos tendientes a la fijación de estos indicadores de acuerdo a las condiciones socioeconómicas de nuestra región.
Servicio Científico Roche
Authors: Pena E. F.
Published: June 2020

Hay pocos campos de la medicina, como ginecología y obstetricia, en que exista una relación tan estrecha entre las enfermedades orgánicas y los trastornos afectivos, El autor, durante los dos últimos años, ha tenido ocasión de asistir a un gran número de pacientes, refugiadas políticas que, además de afecciones orgánicas, presentaban diversas reacciones neuróticas.
Carcinoma In Situ. Diagnostico y manejo Biopsia frente a Cono
Authors: Amorocho P. Néstro H. , Henao P. Fabio
Published: June 2020

Se analizan 119 Historias Clínicas correspondientes a pacientes con diagnósttico de Ca. In situ de Cervix, del Servicio de Ginecología del Hospital de San Juan de Dios de Cali, las cuales se presentaron en el período: Enero 1º de 1970 a Diciembre 31 de 1976. La Biopsia de Cervix sirvió como punto de partida para hacer el estudio retrospectivo hacia la Citología (40% sospechosa 60% positiva) que la motivó y el prospectivo hacia el diagnóstico Histopatológico de la pieza quirúrgica (Histerectomía o Cono). La correlación resultante: CITOLOGIA, BIOPSIA, PIEZA QUIRURGICA lleva a la conclusión que se puede omitir el Cono de rutina, en el manejo del Ca. In situ de Cervix. Este procedimiento es la norma que se sigue en el Hospital de San Juan de Dios de Cali. El margen de error encontrado 4.2% establece un buen índice de seguridad para el tratamiento quirúrgico de estos casos en población hospitalaria, contribuyendo a disminuir los costos que presuponen efectuar Conización de Cervix en forma obligada. El Cono se reserva para tratamiento definitivo en aquellas pacientes que rechazan la extirpación de útero en favor de conservar su función obstétrica. Los casos que resultaron con diagnóstico definitivo de Carcinoma invasor, al seguir la secuencia Citología - Biopsia - Histerectomía, fueron referidos para Cobaltoterapía. Los autores, de acuerdo a su experiencia, recomiendan la prueba de Schiller como un método apropiado y confiable para tomar la Biopsia de Cervix, pero no desconocen la seguridad que brinda la Colposcopia dirigida, utilizada en aquellos centros que poseen equipo y personal entrenado para su correcto uso.
Aborto en América Latina
Authors: Ferguson James , Goldsmith Alfredo
Published: June 2020

En la última década, la comunidad científica ha realizado un esfuerzo para mejorar la tecnología de inducción del aborto (1). Con este objetivo, se han efectuado numerosos estudios para evaluar la diferencia entre métodos, ya sea aspiración por vacío, dilatación y curetaje, o substancias químicas(2).
Badacz jako artysta, artysta jako badacz. Założenia metodologiczne działań artystycznych w procesie badawczym ABR (art-based-research)
Authors: Bielecka-Prus Joanna
Published: June 2020

Postmodernizm, podważając założenia epistemologiczne pozytywizmu i hermeneutyki, wywarł ogromny wpływ na metodologię badań jakościowych. Zatarciu ulegają nie tylko gatunki, ale także granice między dyscyplinami, tak jak to jest w przypadku działań artystycznych w procesie badawczym (ABR – art-based-research), w których badacz posługuje się środkami artystycznymi na różnych etapach zbierania, analizy i prezentacji danych. Problem łączenia sztuki z działaniami badawczymi można rozpatrywać na wielu płaszczyznach. W tym artykule chciałabym skupić się na: 1. Wyjaśnieniu głównych założeń epistemologicznych i metodologicznych badań opartych o sztukę; 2. Omówieniu funkcji ABR w społecznym konstruowaniu wiedzy; 3. Wskazaniu kryteriów, które pozwalają ocenić jakość ABR, oraz trudności, jakie wiążą się z prowadzeniem tego typu badań.
The Sociology of Translation: At the Intersection of Social Sciences and the Humanities. "The Case of The Golden Key, or the Adventures of Buratino"
Authors: Kosman Marcin
Published: June 2020

The article discusses the relationship between translation studies and sociology. It is argued that the latter can prove valuable in a deepened analysis of a given society. Surprisingly, little research has been done with regard to this issue. In order to justify the point of view that translation studies can consort with social sciences in many ways, The Golden Key, or the Adventures of Buratino – a Soviet adaptation of Collodi’s Pinocchio – is analyzed. The choices of the translator are influenced by the trends and norms in the Soviet society. These norms are further analyzed through the lenses of Pierre Bourdieu’s concepts and the Manipulation School. Thus, combining sociology and translation studies can provide an interdisciplinary perspective on social phenomena.
„Socjologia aborcji”. Sposoby przedstawiania aborcji we współczesnym dyskursie nauk społecznych
Authors: Koralewska Inga
Published: June 2020

W niniejszym artykule analizuję współczesny dyskurs nauk społecznych pod kątem obecności w nim badań nad przerywaniem ciąży. Aborcja jest często występującym zabiegiem medycznym, a jednocześnie stanowi jeden z najgorętszych przedmiotów debaty publicznej angażujący środowiska religijne, feministyczne i polityczne. W artykule szukam odpowiedzi na pytanie, czy popularność tego tematu w sferze publicznej znajduje odzwierciedlenie w dyskursie nauk społecznych. Interesuje mnie to, w jaki sposób skupienie dyskursu na konkretnych perspektywach badania aborcji – indywidualnej, społecznej i instytucjonalnej, a także dyskursywnej i metodologicznej – konstruuje „socjologię aborcji”. Analiza dyskursu na temat aborcji pokazuje, że badania nad aborcją w najbardziej prestiżowych czasopismach odnoszą się głównie do świata anglosaskiego. Ponadto badania aborcji stanowią niewielki procent artykułów w analizowanych czasopismach z zakresu nauk społecznych, a dominująca perspektywa to badanie aborcji przez pryzmat opinii społecznych na jej temat. Najmniej uwagi poświęca się natomiast perspektywie indywidualnej i doświadczeniom kobiet, które przerwały ciążę.