bluuebunny/crossref_metadata_2025 huggingface dataset:
Surface Modification of PLLA, PTFE and PVDF with Extreme Ultraviolet (EUV) to Enhance Cell Adhesion
Authors: Lech Adam , Butruk-Raszeja Beata A. , Ciach Tomasz , Lawniczak-Jablonska Krystyna , Kuzmiuk Piotr , Bartnik Andrzej , Wachulak Przemyslaw , Fiedorowicz Henryk
Published: December 2020

Recently, extreme ultraviolet (EUV) radiation has been increasingly used to modify polymers. Properties such as the extremely short absorption lengths in polymers and the very strong interaction of EUV photons with materials may play a key role in achieving new biomaterials. The purpose of the study was to examine the impact of EUV radiation on cell adhesion to the surface of modified polymers that are widely used in medicine: poly(tetrafluoroethylene) (PTFE), poly (vinylidene fluoride) (PVDF), and poly-L-(lactic acid) (PLLA). After EUV surface modification, which has been performed using a home-made laboratory system, changes in surface wettability, morphology, chemical composition and cell adhesion polymers were analyzed. For each of the three polymers, the EUV radiation differently effects the process of endothelial cell adhesion, dependent of the parameters applied in the modification process. In the case of PVDF and PTFE, higher cell number and cellular coverage were obtained after EUV radiation with oxygen. In the case of PLLA, better results were obtained for EUV modification with nitrogen. For all three polymers tested, significant improvements in endothelial cell adhesion after EUV modification have been demonstrated.
A Step Forward in Breast Cancer Research: From a Natural-Like Experimental Model to a Preliminary Photothermal Approach
Authors: Costa Eduardo , Ferreira-Gonçalves Tânia , Cardoso Miguel , Coelho João M. P. , Gaspar Maria Manuela , Faísca Pedro , Ascensão Lia , Cabrita António S. , Reis Catarina Pinto , Figueiredo Isabel V.
Published: December 2020

Breast cancer is one of the most frequently diagnosed malignancies and common causes of cancer death in women. Recent studies suggest that environmental exposures to certain chemicals, such as 7,12-Dimethylbenzanthracene (DMBA), a chemical present in tobacco, may increase the risk of developing breast cancer later in life. The first-line treatments for breast cancer (surgery, chemotherapy or a combination of both) are generally invasive and frequently associated with severe side effects and high comorbidity. Consequently, novel approaches are strongly required to find more natural-like experimental models that better reflect the tumors’ etiology, physiopathology and response to treatments, as well as to find more targeted, efficient and minimally invasive treatments. This study proposes the development and an in deep biological characterization of an experimental model using DMBA-tumor-induction in Sprague-Dawley female rats. Moreover, a photothermal therapy approach using a near-infrared laser coupled with gold nanoparticles was preliminarily assessed. The gold nanoparticles were functionalized with Epidermal Growth Factor, and their physicochemical properties and in vitro effects were characterized. DMBA proved to be a very good and selective inductor of breast cancer, with 100% incidence and inducing an average of 4.7 tumors per animal. Epigenetic analysis showed that tumors classified with worst prognosis were hypomethylated. The tumor-induced rats were then subjected to a preliminary treatment using functionalized gold nanoparticles and its activation by laser (650–900 nm). The treatment outcomes presented very promising alterations in terms of tumor histology, confirming the presence of necrosis in most of the cases. Although this study revealed encouraging results as a breast cancer therapy, it is important to define tumor eligibility and specific efficiency criteria to further assess its application in breast cancer treatment on other species.
The Degree of Cardiac Remodelling before Overload Relief Triggers Different Transcriptome and miRome Signatures during Reverse Remodelling (RR)—Molecular Signature Differ with the Extent of RR
Authors: Rodrigues Patrícia G. , Miranda-Silva Daniela , Li Xidan , Sousa-Mendes Cláudia , Martins-Ferreira Ricardo , Elbeck Zaher , Leite-Moreira Adelino F. , Knöll Ralph , Falcão-Pires Inês
Published: December 2020

This study aims to provide new insights into transcriptome and miRome modifications occurring in cardiac reverse remodelling (RR) upon left ventricle pressure-overload relief in mice. Pressure-overload was established in seven-week-old C57BL/6J-mice by ascending aortic constriction. A debanding (DEB) surgery was performed seven weeks later in half of the banding group (BA). Two weeks later, cardiac function was evaluated through hemodynamics and echocardiography, and the hearts were collected for histology and small/bulk-RNA-sequencing. Pressure-overload relief was confirmed by the normalization of left-ventricle-end-systolic-pressure. DEB animals were separated into two subgroups according to the extent of cardiac remodelling at seven weeks and RR: DEB1 showed an incomplete RR phenotype confirmed by diastolic dysfunction persistence (E/e’ ≥ 16 ms) and increased myocardial fibrosis. At the same time, DEB2 exhibited normal diastolic function and fibrosis, presenting a phenotype closer to myocardial recovery. Nevertheless, both subgroups showed the persistence of cardiomyocytes hypertrophy. Notably, the DEB1 subgroup presented a more severe diastolic dysfunction at the moment of debanding than the DEB2, suggesting a different degree of cardiac remodelling. Transcriptomic and miRomic data, as well as their integrated analysis, revealed significant downregulation in metabolic and hypertrophic related pathways in DEB1 when compared to DEB2 group, including fatty acid β-oxidation, mitochondria L-carnitine shuttle, and nuclear factor of activated T-cells pathways. Moreover, extracellular matrix remodelling, glycan metabolism and inflammation-related pathways were up-regulated in DEB1. The presence of a more severe diastolic dysfunction at the moment of pressure overload-relief on top of cardiac hypertrophy was associated with an incomplete RR. Our transcriptomic approach suggests that a cardiac inflammation, fibrosis, and metabolic-related gene expression dysregulation underlies diastolic dysfunction persistence after pressure-overload relief, despite left ventricular mass regression, as echocardiographically confirmed.
Pregnancy by Assisted Reproductive Technology Is Associated with Shorter Telomere Length in Neonates
Authors: Minamoto Toshiko , Nakayama Kentaro , Ishibashi Tomoka , Ishikawa Masako , Nakamura Kohei , Yamashita Hitomi , Shanta Kamrunnahar , Mahmud Hossain Mohammad , Razia Sultana , Iida Kouji , Sakashita Gyosuke , Nakamura Tsukasa , Kanda Hideyuki , Kyo Satoru
Published: December 2020

Telomere length (TL) influences the development of lifestyle-related diseases, and neonatal TL may influence their prevalence. Various factors have been reported to affect neonatal TL. Although the fetus is exposed to multiple conditions in utero, the main factors affecting the shortening of neonatal TL are still not known. In this study, we sought to identify factors that influence fetal TL. A total of 578 mother-newborn pairs were included for TL analysis. TL was measured in genomic DNA extracted from cord blood samples using quantitative PCR. The clinical factors examined at enrollment included the following intrauterine environmental factors: maternal age, assisted reproductive technology (ART) used, body mass index (BMI), gestational diabetes mellitus (GDM), maternal stress, smoking, alcohol consumption, preterm delivery, small-for-gestational-age, neonatal sex, and placental weight. Univariate and multivariate regression analyses were used to verify the relationship between neonatal TL and these clinical factors. The median neonatal TL to single-copy gene ratio was 1.0. Pregnancy with ART was among the 11 factors associated with shorter neonatal TL. From multiple regression analysis, we determined that neonatal TL was significantly shorter for pregnancies in the ART group than in the other groups. We conclude that pregnancy with ART is associated with shorter neonatal TL.
Lipidation of Antimicrobial Peptides as a Design Strategy for Future Alternatives to Antibiotics
Authors: Rounds Taylor , Straus Suzana K.
Published: December 2020

Multi-drug-resistant bacteria are becoming more prevalent, and treating these bacteria is becoming a global concern. One alternative approach to combat bacterial resistance is to use antimicrobial (AMPs) or host-defense peptides (HDPs) because they possess broad-spectrum activity, function in a variety of ways, and lead to minimal resistance. However, the therapeutic efficacy of HDPs is limited by a number of factors, including systemic toxicity, rapid degradation, and low bioavailability. One approach to circumvent these issues is to use lipidation, i.e., the attachment of one or more fatty acid chains to the amine groups of the N-terminus or a lysine residue of an HDP. In this review, we examined lipidated analogs of 66 different HDPs reported in the literature to determine: (i) whether there is a link between acyl chain length and antibacterial activity; (ii) whether the charge and (iii) the hydrophobicity of the HDP play a role; and (iv) whether acyl chain length and toxicity are related. Overall, the analysis suggests that lipidated HDPs with improved activity over the nonlipidated counterpart had acyl chain lengths of 8–12 carbons. Moreover, active lipidated peptides attached to short HDPs tended to have longer acyl chain lengths. Neither the charge of the parent HDP nor the percent hydrophobicity of the peptide had an apparent significant impact on the antibacterial activity. Finally, the relationship between acyl chain length and toxicity was difficult to determine due to the fact that toxicity is quantified in different ways. The impact of these trends, as well as combined strategies such as the incorporation of d- and non-natural amino acids or alternative approaches, will be discussed in light of how lipidation may play a role in the future development of antimicrobial peptide-based alternatives to current therapeutics.
Polyphenols from Brown Seaweeds (Ochrophyta, Phaeophyceae): Phlorotannins in the Pursuit of Natural Alternatives to Tackle Neurodegeneration
Authors: Barbosa Mariana , Valentão Patrícia , Andrade Paula B.
Published: December 2020

Globally, the burden of neurodegenerative disorders continues to rise, and their multifactorial etiology has been regarded as among the most challenging medical issues. Bioprospecting for seaweed-derived multimodal acting products has earned increasing attention in the fight against neurodegenerative conditions. Phlorotannins (phloroglucinol-based polyphenols exclusively produced by brown seaweeds) are amongst the most promising nature-sourced compounds in terms of functionality, and though research on their neuroprotective properties is still in its infancy, phlorotannins have been found to modulate intricate events within the neuronal network. This review comprehensively covers the available literature on the neuroprotective potential of both isolated phlorotannins and phlorotannin-rich extracts/fractions, highlighting the main key findings and pointing to some potential directions for neuro research ramp-up processes on these marine-derived products.
Cholinergic Chemotransmission and Anesthetic Drug Effects at the Carotid Bodies
Authors: Honing Maarten , Martini Chris , van Velzen Monique , Niesters Marieke , Dahan Albert , Boon Martijn
Published: December 2020

General anesthesia is obtained by administration of potent hypnotics, analgesics and muscle relaxants. Apart from their intended effects (loss of consciousness, pain relief and muscle relaxation), these agents profoundly affect the control of breathing, in part by an effect within the peripheral chemoreflex loop that originates at the carotid bodies. This review assesses the role of cholinergic chemotransmission in the peripheral chemoreflex loop and the mechanisms through which muscle relaxants and hypnotics interfere with peripheral chemosensitivity. Additionally, consequences for clinical practice are discussed.
Role of Copper Oxide on Epoxy Coatings with New Intumescent Polymer-Based Fire Retardant
Authors: Riyazuddin  , Bano Samrin , Husain Fohad Mabood , Siddique Jamal Akhter , Alharbi Khadijah H. , Khan Rais Ahmad , Alsalme Ali
Published: December 2020

Epoxy resins (EP) have been used as a thermos-setting material in the field of coating, casting, bonding agent, and laminating. However, a major drawback associated with its use is the lack of good flaming properties, and it is responsible for heavy smoke along with hazardous gases considerably limiting its uses in various fields. In this study, N-ethanolamine triazine-piperizine, a melamine polymer (ETPMP), was established as a new charring-foaming agent and was successfully synthesized with ethanolamine, piperizine, cyanuric chloride, and melamine as precursor molecules via the nucleophilic substitution reaction method. Elemental analysis and Fourier transform infrared (FTIR) spectroscopy analysis were applied to approve the synthesis of ETPMP and confirmation of its structure and characterization. The epoxy coating of intumescent flame retardant (IFR) was equipped by introducing ETPMP, ammonium polyphosphate (APP), and copper oxide (CuO) in multiple composition ratios. CuO was loaded at various amounts into the IFR-coating system as a synergistic agent. The synergistic action of CuO on IFR coatings was scientifically examined by using different analytical tests such as vertical burning test (UL-94V), limited oxygen index (LOI), thermal gravimetric analysis (TGA), cone calorimeter, and scanning electron microscope (SEM). The results showed that small changes in the amount of CuO expressively amplified the LOI results and enhanced the V-0 ratings in the UL-94V test. The TGA data clearly demonstrate that the inclusion of CuO can transform the thermal deprivation behavior of coatings with a growing char slag proportion with elevated temperatures. Information from cone calorimeter data affirmed that CuO can decrease the burning factors by total heat release (THR) together with peak heat release rate (PHRR). The SEM images indicated that CuO can enrich the power and compression of the intumescent char that restricts the movement of heat and oxygen. Our results demonstrate a positive influence of CuO on the epoxy-headed intumescent flame retardant coatings.
Enhanced Cell-Based Detection of Parvovirus B19V Infectious Units According to Cell Cycle Status
Authors: Ducloux Céline , You Bruno , Langelé Amandine , Goupille Olivier , Payen Emmanuel , Chrétien Stany , Kadri Zahra
Published: December 2020

Human parvovirus B19 (B19V) causes various human diseases, ranging from childhood benign infection to arthropathies, severe anemia and fetal hydrops, depending on the health state and hematological status of the patient. To counteract B19V blood-borne contamination, evaluation of B19 DNA in plasma pools and viral inactivation/removal steps are performed, but nucleic acid testing does not correctly reflect B19V infectivity. There is currently no appropriate cellular model for detection of infectious units of B19V. We describe here an improved cell-based method for detecting B19V infectious units by evaluating its host transcription. We evaluated the ability of various cell lines to support B19V infection. Of all tested, UT7/Epo cell line, UT7/Epo-STI, showed the greatest sensitivity to B19 infection combined with ease of performance. We generated stable clones by limiting dilution on the UT7/Epo-STI cell line with graduated permissiveness for B19V and demonstrated a direct correlation between infectivity and S/G2/M cell cycle stage. Two of the clones tested, B12 and E2, reached sensitivity levels higher than those of UT7/Epo-S1 and CD36+ erythroid progenitor cells. These findings highlight the importance of cell cycle status for sensitivity to B19V, and we propose a promising new straightforward cell-based method for quantifying B19V infectious units.
Artificial Intelligence Methodologies Applied to Prompt Pluvial Flood Estimation and Prediction
Authors: Chang Deng-Lin , Yang Sheng-Hsueh , Hsieh Sheau-Ling , Wang Hui-Jung , Yeh Keh-Chia
Published: December 2020

Regarding urban flooding issues, applying Artificial Intelligence (AI) methodologies can provide a timely prediction of imminent incidences of flash floods. The study aims to develop and deploy an effective real-time pluvial flood forecasting AI platform. The platform integrates rainfall hyetographs embedded with uncertainty analyses as well as hydrological and hydraulic modeling. It establishes a large number synthetic of torrential rainfall events and their simulated flooding datasets. The obtained data contain 6000 sets of color-classified rainfall hyetograph maps and 300,000 simulated flooding maps (water depth) in an urban district. The generated datasets are utilized for AI image processing. Through the AI deep learning classifications, the rainfall hyetograph map feature parameters are detected and extracted. The trained features are applied to predict potential rainfall events, recognize their potential inundated water depths as well as display flooding maps in real-time. The performance assessments of the platform are evaluated by Root Means Square Error (RMSE), Nash Sutcliffe Efficiency Coefficient (NSCE) and Mean Absolute Percentage Error (MAPE). The results of RMSE and NSCE indicators illustrate that the methodologies and approaches of the AI platform are reliable and acceptable. However, the values of MAPE show inconsistency. Ultimately, the platform can perform and be utilized promptly in real-time and ensure sufficient lead time in order to prevent possible flooding hazards.
Prinsip-Prinsip Jual Beli Online dalam Islam dan Penerapannya pada e-Commerce Islam di Indonesia
Authors: Ulum Misbahul
Published: December 2020

E-Commerce di Indonesia telah mengalami perkembangan yang sangat cepat. Banyak situs e-Commerce yang mulai bermunculan seiring dengan perkembangan teknologi informasi dan penetrasi internet di masyarakat. Perkembangan tersebut juga terjadi pada sektor pasar muslim yang ditandai dengan munculnya beberapa e-Commerce Islam. Kemunculan e-Commerce Islam ini sangat bisa dimaklumi mengingat potensi transaksi pada pasar muslim di Indoensia sangat besar, yakni mencapai 2.800 triliun pada tahun 2012. Penelitian ini bertujuan untuk mengetahui sejauh mana prinsip-prinsip jual beli online dalam Islam terimplementasi pada situs e-Commerce Islam di Indonesia, serta untuk mengetahui bagaimana bentuk penerapan prinsip-prinsip jual beli dalam Islam pada praktik transaksi melalui e-Commerce Islam. Penelitian ini adalah penelitian kualitatif dengan pendekatan deskriptif analitis. Teknik pengumpulan data dilakukan melalui observasi langsung dan dokumentasi. Melalui penelitian diharapkan agar praktik jual beli online yang terjadi pada situs e-Commerce Islam benar-benar dijalankan sesuai dengan prinsip-prinsip jual beli dalam Islam.
Pengaruh ROE, Size, dan DER terhadap Harga Saham pada Perusahaan Publik Kategori Restoran, Hotel, dan Pariwisata
Authors: Purba Mora sose , Jamaluddin Jamaluddin , Pinem Herlinta , Sianipar Desi Roulina
Published: December 2020

The increase in return on equity, company size and debt to equity ratio is not always followed by an increase in share prices in trading, service and investment companies listed on the Indonesia Stock Exchange for the 2014-2018 period. This study aims to examine and analyze how the effect of return on equity, company size and debt to equity ratio on stock prices in trading, service and investment companies listed on the Indonesia Stock Exchange for the 2014-2018 period. The research method used in this research uses quantitative research methods with descriptive quantitative research that is explanatory. The population used in this study were all trading, service and investment companies listed on the Indonesia Stock Exchange totaling 129 companies with a sample size of 39 companies with purposive sampling technique. The data analysis method used multiple linear regression.
UPAYA PENCEGAHAN DAN SOLUSI TERHADAP TIMBULNYA PENCEMARAN LINGKUNGAN HIDUP DARI BUANGAN LIMBAH INDUSTRI
Authors: Ratna Anjarsari Siska , Rochmani Rochmani
Published: December 2020

Pencemaran lingkungan hidup akibat buangan limbah industri menjadi perhatian yang tidak pernah surut. Semakin banyak kasus pencemaran lingkungan hidup akibat buangan limbah industri, hal tersebut sangat mengganggu dan meresahkan kehidupan masyarakat serta mengancam kelestarian fungsi lingkungan hidup. Metode penelitian yang digunakan dalam penelitian adalah yuridis normatif dengan melakukan  penelusuran terhadap peraturan-peraturan dan literatur- literatur yang berkaitan dengan permasalahan yang  diteliti. Tujuan penelitian menjelaskan pencegahan dan solusi terhadap timbulnya pencemaran. Hasil penelitian menunjukkan, upaya pencegahan dan solusi terhadap timbulnya pencemaran lingkungan dengan melakukan perencanana proses produksi yang baik, akurat dan cermat mengurangi penggunaan bahan-bahan kimia pembantu yang rendah beban pencemaran,  pengontrolan pemakaian air yang hemat dan efisien, memanfaatkan dan menggunakan kembali (reuse) bahan-bahan kimia yang terdapat dalam limbah cair untuk keperluan produksi serta  berupaya memantau limbah hasil pasca proses kegiatan minimasi limbah.

 

Kata kunci : limbah, lingkungan hidup, pencemaran, pencegahan, solusi.
El Sistema Peruano de Información Jurídica: un aporte eficiente a la revolución digital y el trabajo en un contexto de sistematización jurídica
Authors: ESPINOZA CESPEDES JOSE FRANCISCO
Published: December 2020

La presente investigación busca analizar la importancia del Sistema Peruano de Información Jurídica-SPIJ, como aporte eficiente a la revolución digital y el trabajo en un contexto de sistematización jurídica. En dicho ámbito se determinará la aplicación del SPIJ en relación a la informática jurídica aplicable al Derecho al Trabajo. Finalmente, se buscará conocer la incidencia del SPIJ como elemento técnico para la sistematización jurídica de la normatividad relativa al mundo del trabajo, específicamente a nivel de la regulación del teletrabajo.
Caracterización de competencias profesionales necesarias para los médicos calificadores de la pérdida de la capacidad laboral y ocupacional en Colombia
Authors: Suárez Hermes Rodolfo
Published: December 2020

El presente artículo, producto de la Línea de investigación “Modelo de acompañamiento para la formación integral” desarrollada como estudiante en la Maestría en Educación de la Corporación Universitaria Minuto de Dios; investigación que busca identificar las competencias profesionales del médico para calificar la invalidez, respecto a las enfermedades, en el marco colombiano de la Seguridad Social. Dicho estudio, parte del saber médico y los aspectos legales de la calificación, revisando los planes posgraduales en Salud Ocupacional, y consultado con médicos que integran las Juntas de Calificación de Invalidez, sobre las competencias para calificar y las necesidades de formación. Teniendo en cuenta los resultados, se puede evidenciar que, si bien los programas hacen énfasis en la prevención de la enfermedad laboral, no se desarrolla a profundidad la formación en calificación; teniendo en cuenta esto, es evidente la necesidad de crear planes posgraduales que incluyan competencias y saberes para el actuar médico en calificación, con responsabilidad social y ética.
Derecho de los trabajadores a la desconexión digital: mail on holiday
Authors: Pérez Amorós Francisco
Published: December 2020

El derecho a la desconexión digital el los trabajadores fuera de jornada, reconocido en 2018, faculta al trabajador a no responder a las comunicaciones de trabajo del empresario que reciba fuera del horario laboral. El reconocimiento ha suscitado comentarios positivos, pero también algunas críticas por una ambigüedad. La desconexión legal –en el contexto digital- pretende evitar prolongaciones indebidas de la jornada que puedan menoscabar el descanso, la conciliación familiar, la salud, y la intimidad (derecho  fundamental).
Defunding the ramparts and institutional theory: The master’s tools will fell the master’s house
Authors: DeValve Michael J.
Published: December 2020

Witnessing current events in Ferguson, and now in Milwaukee, New York, Los Angeles, Seattle, of course Portland, and now Kenosha, Wisconsin, where protests against police violence are met with yet more police violence, the question naturally arises: Why are police so seemingly insistent on actively working counter to their own organizational best interest? This essay poses this troubling question and derives part of an answer for it from institutional theory.
Escola de Belas Artes da Universidade Federal do Rio de Janeiro - Criação de website institucional
Authors: Oliveira Ana Karla Freire de , Backx Hugo Borges , Grimaldi Madalena Ribeiro
Published: December 2020

Este artigo descreve o planejamento e implementação do website de comunicação institucional da Escola de Belas Artes da Universidade Federal do Rio de Janeiro. Esta iniciativa foi uma das ações comemorativas dos 200 anos da Instituição, pioneira no ensino das Artes na América Latina. O trabalho ocorreu de forma transdisciplinar, agregando conhecimentos de Design, Informática e Artes. Na definição do projeto gráfico buscou-se um layout que possibilitasse a navegação e pesquisa mais acessíveis e simplificadas, e em consonância com as áreas de conhecimento existentes na Escola: Artes e Design. Para melhor contextualização apresenta-se um breve histórico da Instituição, a arquitetura de informação adotada para o website, seu layout e funcionamento. As ações foram pensadas para dar melhor visibilidade e funcionalidade a complexa estrutura que compõe a Unidade, com seus 13 cursos de Graduação, dois Programas de Pós-Graduação e duas Especializações.
Capa
Authors: Soares Silva Maria Rennally
Published: December 2020

Capa
Logos und Glaube im “secular age.”
Authors: Jagiełło Jarosław
Published: December 2020

The chief motivation for undertaking this research comes from my encounter with Charles Taylor’s excellent work, “A Secular Age,” in which he not only analyzes the various historical manifestations of secularization in Western civilization, but also—and above all—tries to identify the newly emerging conditions in which forms of religious belief may develop on the threshold of the new millennium, in the context of what he himself describes as a secular age.

My paper chiefly focuses on the fact that the routes leading to, and attempts to bring about, a revival of Christian spirituality in the modern world, which Taylor describes in his book, were already a concern for many philosophers working at the start of the 20th century. One amongst these, the Austrian thinker Ferdinand Ebner, occupies a special position.

Known to the philosophical world as one of the originators of dialogical thinking, Ebner uncovers the real key to the revitalization and consolidation of Christian spirituality in the form of the reality of the spoken word. First and foremost, his philosophy of the word constitutes a spectacular example of the intensive search for meaning in life: something not always easy for human beings in a secular age to discover and define for themselves. In this paper I also aim to present the basis for Ebner’s assertion of an inseparable link between the word and religious faith, and to show how this relationship founds a possibility for the renewal of Christian spirituality in the modern world.
Optimasi Decision Tree menggunakan Particle Swarm Optimization untuk klasifikasi sel Pap Smear
Authors: Arifin Toni
Published: December 2020

Penelitian ini menyajikan klasifikasi sel Pap Smear. Data yang digunakan adalah dataset Herlev yang berjumlah 917 data. Penelitian ini bertujuan untuk mengetahui apakah penggunaan algoritma optimasi particle swarm optimization dapat meningkatkan kinerja dari algoritma Decision tree dalam mengklasifikasikan data Sel Pap Smear. Tahapan dari penelitian ini adalah preprocessing, feature optimization, knowledge rules, evaluation dan performance report. Hasil dari penelitian ini menunjukkan bahwa algoritma Decision tree menghasilkan akurasi sebesar 91.39 % dengan AUC 0.858,  sedangkan penerapan algoritma particle swarm optimization pada Decision tree menghasilkan akurasi yang lebih baik yaitu sebesar 96.76 % dengan AUC 0.926.
Analisis Manajemen Risiko Teknologi Informasi Policy Service PT. Asuransi Sinar Mas Menggunakan Framework COBIT 5
Authors: Wibawa Marco Putra , Manuputty Augie David
Published: December 2020

Penelitian ini dilakukan bertujuan untuk mengetahui kondisi penerapan manajemen risiko dan mengidentifikasi ancaman risiko terhadap proses bisnis di PT. Asuransi Sinar Mas. Hal ini dikarenakan untuk analisis manajemen risiko sudah menjadi hal yan patut diperhitungkan oleh suatu perusahaan dalam meningkatkan keuntungan dan asset perusahaan yang akan selalu menjadi bagian penting dalam suatu perusahaan. Untuk mengetahui seberapa pengaruh manajemen risiko bagi Divisi Policy Service di PT. Asuransi Sinar Mas, maka perlu dilakukan pengujian terhadap kondisi penerapan manajemen risiko yang sudah berjalan pada perusahaan tersebut. Penelitian ini penulis menggunakan metode Mix Method, untuk pengumpulan data penulis menggunakan metode kuantitatif yang disebarkan kepada 18 responden. Kemudian untuk melengkapi data Kuantitatif tersebut penulis juga melakukan wawancara terhadap Kepala Departemen Divisi Policy Service. Pada tahap mendapatkan nilai capability level penulis menggunakan framework COBIT 5. Dalam framework COBIT 5 penulis menggunakan 2 subdomain yaitu APO12 dan MEA01. Pada subdomain APO12 memiliki 6 karakter nilai yang berbeda beda sedangkan untuk MEA01 mendapatkan nilai 3,78 yang memiliki gap 1,22 dari nilai yang diharapkan perusahaan. Walupun dari nilai yang didapat sudah cukup baik, namun akan lebih baik apa bila dilakukan pengingkatan dalam analisis manajemen risiko pada perusahaan agar dapat mempertahankan posisi perusahaan  dan bersaing dengan perusahaan lain yang memiliki kesamaan dalam bidang jasa .
Analysis and Design of Coil Rolling Machines on Robot Solenoids using Macroergonomic Analysis Method and Design (MEAD) and Rapid Entire Body Assesment (REBA) Based on Arduino Microcontroller
Authors: Sukendar Irwan , Arifin Bustanul , Addin Faathir Sukron
Published: December 2020

The making of Indonesian soccer robot in the division of the Indonesian Football Robot Contest (KRSBI) especially in the process of coil rolling machines on a solenoid does not pay attention to ergonomic factors. The process of winding the wire on the solenoid is done using only the hands manually and in an un ergonomic body position, which is turning and bending. As a result, the convolution process lasts longer and in the wrong posture, causing fatigue and back pain. Macroergonomic Analysis and Design (MEAD) and Rapid Entire Body Assessment (REBA) approaches are used to analyze the posture of the wire. The solution is obtained by design and making an ergonomic and semi-automatic coil rolling machines to solenoid Robot based on the Arduino Microcontroller
The Reliability Analysis of Rotary Kiln A
Authors: Uli Hotma , Ikhsan Muhammad Rizky , Pratama Setyo Yulio
Published: December 2020

Rotary Kiln as a pyroprocessing device is used to raise the temperature of the material to a high temperature (calcination) in a continuous process. By looking at the constraints on PT. Meratus Jaya Iron & Steel, whose production machines often have breakdowns, is a fundamental reason for researchers to increase the reliability level of PT. Meratus Jaya Iron & Steel. The research was conducted on the Rotary Kiln Machine made in Germany which plays a high enough role in the company. The method used is the Reliability with Mean Time to Repair Method (MTTR). From the results of calculations of Reliability with MTTR on Rotary Kiln A is Reliability at the time of 296 hours operation results obtained by 0.5371 and MTTR 537.7732. The higher the reliability value, the better the machine used in the operation process.
The Conceptual View of StreamEPS
Authors: Appiah Frank
Published: December 2020

These Event processing systems are much used in wide variety of applications in the processing of large stream of
events. The most distinguished of applications is the time-series data management system with timely processing to identify trends, pattern matches and forecast future values.The complexity of event information, coupled with the fact that historical event data is being kept in the database, requires the use of an event processing model that provides the user with high-level abstractions. In this paper, I survey the StreamEPS to help developers and researchers alike to understand the conceptual
view and processing of the event processing software system. StreamEPS forms part of Complex EventProcessing (CEP),

Data Stream Management System (DSMS) and Information Flow Processing (IFP) domain.
The Custodians of the Gift
Authors: Pigliasco Guido Carlo
Published: December 2020

Emerging from more than two decades of research in the field and in the archives, the essays collected here explore the multifaceted topic of the Fijian firewalking ceremony, the vilavilairevo. The collection examines the intersection of the intertwined topics of cultural property, reproduction of tradition, and change with issues of (post)colonial representation, authenticity, and ethnic identity. The essays advance new insights on the tourist gaze and the safeguarding of intangible cultural heritage and pose serious questions regarding the role of digital and social media as tools for preserving cultural legacies and extending traditional cultural worlds into new domains. Focusing on the response of the Sawau tribe of the island of Beqa to the commodification of the vilavilairevo as their iconic practice, this essay collection ultimately illuminates how the Christian cultural dynamics and unprecedented dogmatic schism surrounding the vilavilairevo spectacle are reshaping local notions of heritage, social sentiment, and social capital.
Students’ English Lesson Attitudes and Its Effects on their English Achievement
Authors: Wiwaharini Yuditha Putri
Published: December 2020

This research is aimed to analyze students’ English lesson attitude and its effect on their English achievement. This research is a pre-experimental and it was carried out at one joint-cooperation school in Surabaya, Indonesia. Since English is the language that mostly used at the joint-cooperation school, the parents that sent their children there must have high expectations of their children’s English ability. This pressure can affect the students in learning English in the class. Some students will have negative attitudes in learning English because their parents do not want them to fail. Therefore, the researcher took a sample of 17 students in grade 3 as her subjects. The writer used a questionnaire to measure students’ attitude towards English lesson and compare it with students’ English score. The result shows that students’ attitudes do affect their English achievement. Those students who have positive attitudes towards English will stimulate their mood to absorb the information better.
Developing Educational Game as Language Acquisition Media for Young Learners
Authors: Setyawan Farid Helmi , Susanto Sofyan
Published: December 2020

Language acquisition is the process of language mastery done by children naturally when they learn their mother of tongue. The era of globalization with the presence of sophisticated technology requires children to be able to use technology well. With the presence of technology, it makes it easy for children to learn many things, especially languages. The purpose of using language learning media based on the educational game culture character of the android system is to increase language acquisition for early childhood. With this language learning media, early childhood is helped in understanding and mastering verbal vocabulary. In addition, in this era, many people have Smart Phones that can load various applications. In addition, it is very easy for parents to access or open an android-based media application from their Smart Phones. The research method used is research and development. This development was carried out in the learning media, namely language learning media based on the educational character of the culture system of the android system. This study uses the Borg and Gall development theory which has been simplified into six stages. This research was conducted at PAUD / TK in the Ngawi Regency, East Java. The research subjects are early childhood and parents in PAUD/TK Ngawi Regency with a total of 50 people. The results of this study are in the form of educational learning applications based on the educational game culture character of the Android system. The results of the data analysis showed that, from 50 respondents who are parents of children, 44 people stated that the media ere feasible and very useful and 45 people gave positive responses. From the results of the addition of the acquisition of children's language shows 46 children experienced progress and the addition of the acquisition of a new language. The results of this study are expected to facilitate early childhood in language acquisition
Problems in Teaching Tourism Register for English Specific Purposes (ESP) Class
Authors: Claria Dewa Ayu Kadek , Warmadewi A.A. Istri Manik
Published: December 2020

The purpose of this research was to find out the problems in teaching tourism register in English Specific Purposes (ESP) class. Students are expected to know the tourism register as the new group of vocabulary and being able to use them in the related field. When the tourism register is implanted in the course, there were some problems appeared. By reading many literatures related to the topic, the problems can be investigated. It was found that there are some problems which influenced the teaching method in ESP class. The problems can be generalized into two main problems namely; the lecturer’s problems and student’s problems. The lecturer’s problems consist of ineffective teaching and learning method includes the design material which is not fit enough for some ESP students. The student’s problems are divided into the student English proficiency, lack of vocabulary, lack of motivation and basic skill in reading, writing, listening and speaking skills.
ESP Learner Motivations and Perceptions towards International Online Letter Exchange Program
Authors: Ruminar Hafida , Gayatri Putri , Prasetyaningrum Dian Islami
Published: December 2020

The Online Letter Exchange Program (OLEP) was an online collaborative learning program hosted by the Faculty of Agriculture of the University of Miyazaki, Japan. It has collaborated with the Faculty of Agriculture in one of the private universities in Malang. The program is designed to encourage students’ written communication skills and facilitate students with intensive real-life English communication experience with other students around Asia. The participant countries are from Japan, Taiwan, China, and Indonesia. One of its uniqueness lies in the policy that the participants share their specific fields, including agriculture and related fields. This study sought to investigate the intrinsic and extrinsic motivation and perception of the students towards the OLEP as it was supplementary activity. The perception included the topic, the platform, and interaction. The data were gained from questionnaires and interviews and were then analyzed using thematic analysis. The result showed that extrinsic motivation was dominant in completing the task in OLEP. The positive and negative perception of the three aspects would be a valuable source for those who attempt a similar online letter exchange program
O que, como e por que censurar
Authors: Cesco Susana
Published: December 2020

A censura foi uma ferramenta importante do projeto político dos governos ditatoriais de 1964 a 1985. Este texto analisa os caminhos percorridos pela política de controle estatal, especialmente no que diz respeito às normas e critérios adotados para proibir e cercear a livre circulação de ideias. A abordagem recai no trabalho de censores, autoridades policiais e na própria reestruturação e atuação da Polícia Federal nas décadas de 1960 e 1970 que passou a atuar como órgão responsável pela censura no país. Para esse estudo tem-se por base dois documentos elaborados no ano de 1970, intitulados “Normas Gerais - recomendação verbal à imprensa falada, escrita e televisionada” e “Instruções para a Execução da Censura à Posteriori”, além de documentos administrativos da Polícia Federal que direcionaram a atuação dos censores e relataram seus resultados.
Morcegos e o ensino de Ciências: a percepção dos professores e a aplicação em sala de aula
Authors: Silva Crislaine Maria da , Silva Luiz Augustinho Menezes da
Published: December 2020

Os morcegos são mamíferos voadores envoltos em vários mitos, sendo o mais conhecido o vampirismo. Esta pesquisa busca identificar como o conteúdo morcegos é trabalhado e percebido pelos professores de Ciências em dois municípios pernambucanos. Foi aplicado um questionário com questões abertas aos professores que ensinam ciências da rede pública de ensino fundamental, quanto a sua formação, tempo de trabalho, sobre as notícias, os mitos, a importância dos morcegos, como os livros abordam acerca dos quirópteros e como o conteúdo é trabalhado em sala de aula. Em seguida, foi realizada uma analise quali/quantitativa utilizando o método do Discurso do Sujeito Coletivo. Dos 38 professores entrevistados, sete se recusaram a responder ao questionário, 22 possuem graduação, oito mestrado e três estão no doutorado. Na concepção foram ressaltados pontos negativos relacionados aos morcegos e afirmam não ser comum trabalhar o tema nas escolas, as fontes de informação mais citadas (Universidade, livros e documentários). Os professores usaram informações classificatórias, ecológicas, comportamental e o hábito. Em linhas gerais, esse estudo demonstrou a necessidade na abordagem de temas como esse em sala de aula, uma vez que os morcegos são cercados de mitos, em muitos casos tratados como sem importância e perseguidos pela população.
A Embriologia Humana, sob uma perspectiva temporal, nos livros didáticos de Ciências: uma análise do conteúdo e das imagens
Authors: Griep Maronn Tainá , Do Espírito Santo Hermel Erica
Published: December 2020

Esse trabalho apresenta como objetivo analisar o conteúdo e as imagens sobre a embriologia humana nos livros didáticos de Ciências publicados no Brasil a partir de 1980. Na análise do conteúdo teórico foram considerados os seguintes parâmetros (adequação à série; clareza do texto; nível de atualização do texto; grau de coerência entre as informações apresentadas; e se apresenta ou não textos complementares) e critérios (fraco; regular; bom; e excelente). As atividades propostas (questões propostas; atividades práticas; estímulo a novas tecnologias; trabalhos em grupo; entre outros) e os recursos adicionais ou complementares (glossários; atlas; cadernos de exercícios; guias de experimentos; guia do professor; entre outros). As imagens foram classificadas quanto ao grau de iconografia, funcionalidade, relação com o texto principal, etiquetas verbais e conteúdo científico. Com relação ao conteúdo, os livros, ao longo do tempo, apresentaram mais conceitos relacionados a embriologia, além de mais recursos adicionais ou complementares. Nas imagens, observou-se uma predominância de imagens do tipo ilustração (esquemas, 91), informativas (143), denotativas (138), com etiquetas verbais relacionais (150) e modelo cientificamente correto (284). Percebeu-se uma evolução nos livros didáticos em relação ao conteúdo de embriologia humana apresentado, porém ainda é necessário que sejam aperfeiçoados.
Termoquímica na perspectiva CTSA para o ensino de química por meio das TIC
Authors: Pereira Linney Chrissie Konno Piton , Wobeto Carmen , Junior Felicio Guilardi , Rosinke Patrícia
Published: December 2020

Esta pesquisa apresenta o desenvolvimento de uma proposta de ensino investigativo de termoquímica na perspectiva Ciência-Tecnologia-Sociedade-Ambiente (CTSA), cujo desenvolvimento se deu por meio das Tecnologias da Informação e Comunicação (TIC) em diversos canais de comunicação que viabilizaram a aprendizagem remota. Tais ferramentas digitais possibilitaram o ensino durante o isolamento social ocasionado pela pandemia COVID-19 e suspensão de atividades presenciais nas escolas. As aulas contaram com a participação de dois grupos de alunos matriculados no segundo ano do ensino médio de uma escola da rede estadual do município de Colíder, Mato Grosso. As atividades síncronas foram divididas em três momentos didáticos de duas horas cada, nas quais os participantes foram motivados ao questionamento visando a construção da argumentação crítica. Observamos a sensibilização quanto aos conceitos estudados de termoquímica associados as calorias, alimentação saudável e hábitos alimentares, com um olhar especial durante esse período de isolamento.
СДЕЛКА КАК ГРАЖДАНСКО-ПРАВОВАЯ КАТЕГОРИЯ
Authors: Нинциева Т.М.
Published: December 2020

Статья посвящена анализу гражданско-правовой категории «сделка». Актуальность исследования заключается в том, что в данной статье предельно чётко получили своё описание виды сделок и правовые основания их заключения. Статья предназначена для студентов и преподавателей юридических факультетов, а также для тех, кто интересуется вопросами гражданского права.
СООТНОШЕНИЕ КАТЕГОРИЙ «УБЫТКИ», «УЩЕРБ» И «ВРЕД»: АНАЛИЗ ЗАКОНОДАТЕЛЬСТВА, ДОКТРИНЫ И СУДЕБНОЙ ПРАКТИКИ
Authors: Идрисов Х.В.
Published: December 2020

Статья посвящена правовому анализу таких юридических категорий, как «убытки», «ущерб» и «вред» в контексте употребления их в нормах Гражданского кодекса РФ. Несмотря на то, что гражданское законодательство приводит легальную дефиницию понятия «убытки», остается непонятным вопрос дефиниций понятий «ущерб» и «вред» в рамках норм Гражданского кодекса РФ.
В статье приводятся доктринальные мнения относительно рассматриваемого вопроса, анализ нормативно-правовой базы и рассматриваются примеры из судебной практики, раскрывающие предмет данной статьи.
В заключение статьи делается вывод о том, что понятия «убытки», «ущерб» и «вред», характеризующие негативные последствия в сфере имущественного положения потерпевшего (кредитора), не являются тождественными юридическими категориями, а представляют собойразновидовые понятия одного родового свойства.
ИННОВАЦИОННАЯ ДЕЯТЕЛЬНОСТЬ СТУДЕНТОВ В КОНТЕКСТЕ КОМПЕТЕНТНОСТНОГО ПОДХОДА
Authors: Даудов Э.Х. , Абдулазимова Т.Х.
Published: December 2020

В статье изучена сущность инновационной деятельности студентов вуза в контексте компетентностного подхода, изучены понятия «инновация» и «инновационная деятельность», выявлено, что внедрение образовательных стандартов нового поколения обусловило смену парадигмы, преобладающее место в которой отведена компетентностному подходу. Современные реалии диктуют актуальную необходимость подготовки компетентностного и конкурентоспособного специалиста как креативной и творческой личности, способной к автономному и независимому принятию решений, генерированию и продуцированию новых идей, созданию инновационных продуктов, принимать ответственность за результаты своей деятельности, проектировать непрерывный план личностного и профессионального самосовершенствования.
ПРИЧИНЫ И ФАКТОРЫ РАЗВИТИЯ НИЗКОЙ САМООЦЕНКИ И НЕУВЕРЕННОСТИ В СЕБЕ В ЮНОШЕСКОМ ВОЗРАСТЕ
Authors: Керимова Р.М. , Арскиева З.А.
Published: December 2020

В данной статье мы рассматриваем причины развития неуверенности и заниженной самооценки у подростков. Говорится о причинах, связанных с низкой оценкой подростка, которое выражается в сфере межличностных контактов, неуверенностью в своих интеллектуальных способностях и внешней привлекательности, что может привести к чрезмерному влиянию сверстников, замедлить развитие, снизить мотивацию достижения целей. Результаты исследования могут быть использованы при разработке программ профилактики и развития оптимизма в юношеской среде. Авторы также поясняют возможные факторы, способствующие развитию, а также и снижению самооценки подростков благодаря воздействию родителей.