bluuebunny/crossref_metadata_2025 huggingface dataset:
Growth and Development of Ecotypes of Arabidopsis thaliana: Preliminary Experiments to Prepare for a Moon Lander Mission
Authors: Shymanovich Tatsiana , Kiss John Z.
Published: May 2020

NASA is planning to launch robotic landers to the Moon as part of the Artemis lunar program. We have proposed sending a greenhouse housed in a 1U CubeSat as part of one of these robotic missions. A major issue with these small landers is the limited power resources that do not allow for a narrow temperature range that we had on previous spaceflight missions with plants. Thus, the goal of this project was to extend this temperature range, allowing for greater flexibility in terms of hardware development for growing plants on the Moon. Our working hypothesis was that a mixture of ecotypes of Arabidopsis thaliana from colder and warmer climates would allow us to have successful growth of seedlings. However, our results did not support this hypothesis as a single genotype, Columbia (Col-0), had the best seed germination, growth, and development at the widest temperature range (11–25 °C). Based on results to date, we plan on using the Columbia ecotype, which will allow engineers greater flexibility in designing a thermal system. We plan to establish the parameters of growing plants in the lunar environment, and this goal is important for using plants in a bioregenerative life support system needed for human exploration on the Moon.
Partitioning evapotranspiration using stable isotopes and Lagrangian dispersion analysis in a small agricultural catchment
Authors: Hogan Patrick , Parajka Juraj , Heng Lee , Strauss Peter , Blöschl Günter
Published: May 2020

Measuring evaporation and transpiration at the field scale is complicated due to the heterogeneity of the environment, with point measurements requiring upscaling and field measurements such as eddy covariance measuring only the evapotranspiration. During the summer of 2014 an eddy covariance device was used to measure the evapotranspiration of a growing maize field at the HOAL catchment. The stable isotope technique and a Lagrangian near field theory (LNF) were then utilized to partition the evapotranspiration into evaporation and transpiration, using the concentration and isotopic ratio of water vapour within the canopy. The stable isotope estimates of the daily averages of the fraction of evapotranspiration (Ft) ranged from 43.0–88.5%, with an average value of 67.5%, while with the LNF method, Ft was found to range from 52.3–91.5% with an average value of 73.5%. Two different parameterizations for the turbulent statistics were used, with both giving similar R
2 values, 0.65 and 0.63 for the Raupach and Leuning parameterizations, with the Raupach version performing slightly better. The stable isotope method demonstrated itself to be a more robust method, returning larger amounts of useable data, however this is limited by the requirement of much more additional data.
Multi-model climatic water balance prediction in the Zala River Basin (Hungary) based on a modified Budyko framework
Authors: Csáki Péter , Gyimóthy Kitti , Kalicz Péter , Szolgay Ján , Zagyvai-Kiss Katalin Anita , Gribovszki Zoltán
Published: May 2020

Providing information on the impacts of climate change on hydrological processes is becoming ever more critical. Modelling and evaluating the expected changes of the water resources over different spatial and time scales can be useful in several fields, e.g. agriculture, forestry and water management. Previously a Budyko-type spatially distributed long-term climate-runoff model was developed for Hungary. This research includes the validation of the model using historical precipitation and streamflow measurements for three nested sub-catchments of the Zala River Basin (Hungary), an essential runoff contributing region to Lake Balaton (the largest shallow lake in Central Europe). The differences between the calculated (from water balance) and the estimated (by the model) mean annual evapotranspiration varied between 0.4% and 3.6% in the validation periods in the sub-catchments examined. Predictions of the main components of the water balance (evapotranspiration and runoff) for the Zala Basin are also presented in this study using precipitation and temperature results of 12 regional climate model simulations (A1B scenario) as input data. According to the projections, the mean annual temperature will be higher from period to period (2011–2040, 2041–2070, 2071–2100), while the change of the annual precipitation sum is not significant. The mean annual evapotranspiration rate is expected to increase slightly during the 21st century, while for runoff a substantial decrease can be anticipated which may exceed 40% by 2071–2100 relative to the reference period (1981–2010). As a result of this predicted reduction, the runoff from the Zala Basin may not be enough to balance the increased evaporation rate of Lake Balaton, transforming it into a closed lake without outflow.
Characterisation of classical enterotoxins, virulence activity, and antibiotic susceptibility of Staphylococcus aureus isolated from Thai fermented pork sausages, clinical samples, and healthy carriers in northeastern Thailand
Authors: Sankomkai Wanwisa , Boonyanugomol Wongwarut , Kraisriwattana Kairin , Nutchanon Julalak , Boonsam Kraisorn , Kaewbutra Sasalux , Wongboot Warawan
Published: May 2020

Introduction

Contamination by Staphylococcus aureus of food produced from animal sources may have diverse and multifactorial causes that depend on geographical distribution. The goal of this study was to isolate and characterise S. aureus strains from contaminated fermented pork sausage, which is a local food of northeastern Thailand.

Material and Methods

S. aureus strains were isolated from local pork sausage, and the presence of classical enterotoxins was determined by PCR and reversed passive latex agglutination. These results were compared with strains derived from hospitalised patients and healthy carriers. Additionally, production of extracellular enzymes and haemolysin, biofilm formation, and antibiotic susceptibility were assessed.

Results

S. aureus was identified in 36 sausage isolates (60%). The strains positive for staphylococcal enterotoxin A were more frequently found in isolates from sausage and healthy carriers than in those from patients. All tested S. aureus strains were positive for DNase, lipase, proteinase, haemolysin, and biofilm formation; notably, strains isolated from food and healthy carriers displayed similar values. Most isolates were resistant to penicillin and ampicillin, while none were to methicillin.

Conclusions

Thai fermented pork sausages are associated with a high risk of staphylococcal food poisoning, which may be linked to contamination caused by carriers. Dissemination of knowledge regarding best practices in sanitation and hygiene is important in local communities.
Das 500. Reformationsjubiläum in rumänisch-orthodoxer Wahrnehmung. Barometer für den aktuellen Stand der Ökumenischen Bewegung?
Authors: Fröhlich Hans Bruno
Published: May 2020

In my article I would like to document assessments from the 500th anniversary of the Reformation in the perception of the Romanian Orthodoxy. From these evaluations, conclusions about the current position of Orthodoxy to Protestantism can be drawn. The focus is on a total of seven contributions. Two are from the online news portal of the Bucharest Patriarchate www.basilica.ro by Gheorghe Anghel and Aurelian Iftimiu. Three articles were published in the “Revista Teologică” from Theological Faculty in Sibiu by Daniel Buda & Aurel Pavel, Mihai Iordache and Maria Curtean. Finally, I’m referencing to two contributions published by the Bucharest theologian Cosmin Pricop in German-language publications.
The Labour Market Crisis in Romania Causes, Effects and Potential Solutions
Authors: Ioan Cindrea
Published: May 2020

We are going through troubled times, with worldwide pandemic crises affecting us altogether: citizens, companies and states. This article presents analyses and solutions to the workforce crisis of December 2019 and the workplace crisis of March 2020. Things have escalated from a workforce crisis to a new stage, namely an accelerated loss of workplaces and to a workplace crisis. In a matter of weeks, the labour market has moved from one extreme to the other extremely fast because of a very rough natural phenomenon which could not have been predicted, i.e. the global pandemic crisis caused by the COVID-19 coronavirus. It goes without saying that we all wish to achieve a relative balance on the labour market. This study puts forward concrete solutions adapted to the situation of the Romanian labour market at the end of 2019, when we saw a significant workforce crisis which severely affected companies’ business development objectives. At the same time, it introduces 11 solutions to the new job crisis, which is quickly expanding as a result of the global pandemic caused by the COVID-19 virus and by the declaration of a state of emergency in Romania. In a few weeks of crisis, Romania went from minus 1 million workers to plus 1 million workers. This is an extremely difficult situation. However, I believe that it is temporary and that after the pandemic crisis both the economy and the labour market will gradually recover.
Does Exchange Rate Have Asymmetric Impact on Trade Balance? Fresh Insights from Combined Cointegration
Authors: Nathaniel Solomon Prince
Published: May 2020

The study examines the asymmetric impact of exchange rate on the trade balance in Nigeria relying of time series data that spans 1960-2016. The Non-linear ARDL bounds test and the Bayer and Hanck (2013) test established a cointegrating relationship among the variables after accounting for structural break in the series. The Block Exogeneity Wald Tests affirmed the bidirectional causality between the variables. Findings establish the asymmetric impact of exchange rate on the trade balance in Nigeria, but unable to confirm the existence of the J-curve Phenomenon. This reveals that the devaluation of the Naira may not be a viable decision if the intention is to curb the persistent deficit in the country’s trade balance. Policies that could help curtail these deficits and enhance sustainable growth were suggested.
Repeatability of growth characteristics and wood properties for solid wood production from Eucalyptus camaldulensis half-sib families growing in Thailand
Authors: Nezu Ikumi , Ishiguri Futoshi , Aiso Haruna , Diloksumpun Sapit , Ohshima Jyunichi , Iizuka Kazuya , Yokota Shinso
Published: May 2020

To promote solid wood production, the diameter at breast height, height, stress-wave velocity, surface-released strain, basic density and compressive strength parallel to the grain were measured for 10 half-sib families of 12-year-old Eucalyptus camaldulensis Dehnh. trees growing in Thailand. Based on the results, growth rates, correlations among measured properties, radial and among-family variations of wood properties, and their repeatability were evaluated. Diameter at breast height, height, and wood volume were exponentially increased at initial stage, and then gradually increased toward to 12 years after planting. The maximum current annual increment and mean annual increment in wood volume showed at age of 8 and 11years old, suggesting that rotation period for optimum productivity may be ranged from 8 to 11 years old. Wood with stable properties was found greater than 6 cm from the pith. These results indicate that 12-year-old E. camaldulensis trees had already reached the maturation stage. No significant correlations were found between growth characteristics and wood properties. Significant variances in the height, stress-wave velocity, and basic density were found among the 10 families. The F-values and repeatability of the wood properties in the outer wood were higher than those in the inner wood. These results indicate that the properties of the outer wood are closely related to genetic factors. Thus, to obtain superior E. camaldulensis trees for solid wood production, the family selection should be conducted using the outer wood of aged trees.
LEGAL RECONSTRUCTION OF IMPLEMENTATION LEGALLY BINDING VERDICT IN INDUSTRIAL RELATIONS COURT
Authors: Putra Sri Gilang Muhammad Sultan Rahma
Published: May 2020

The existence of industrial relations courts until now still can not provide adequate legal protection to justice seekers. This article begins with the existing legal problems in the form of not implemented legally binding of industrial relations court verdicts. The unapplied verdicts have resulted in the exclusion of the rights of justice seekers. This paper identifies the problem related to normative perspective and provide solutions through legal reconstruction from the normative view. Then, the problems are examined using normative legal research methods based on statute approach and historical approach as well as case approach. By examining several research results it is known that the legal vacuum which regulates sanctions against those who do not intend to enforce industrial relations court rulings that have legal force still need to be addressed immediately to guarantee the rights of the seekers of justice in the industrial relations court. This paper recommends to establish a Supreme Court Regulation on the implementation of institutional force on industrial relations disputes cases and the need for amendment of Law Number 2 Year 2004 on Industrial Relations Dispute Settlement.
DOES ORAL PRESENTATION AFFECT THE DEVELOPMENT OF THE STUDENTS’ ABILITY TO SPEAK IN EFL CLASSROOM?
Authors: Riadil Ikrar Genidal
Published: May 2020

Oral Presentation is one of ways to develop the speaking ability. This study focuses on the impact of oral presentation toward speaking ability based on the student’s point of view in EFL classroom for higher education. The purpose of this study were to investigate the impact of oral presentation to the development of the students ability to speak English and know the student’s difficulties in doing oral presentation in EFL classroom for higher education. From the purpose of this study, the researcher formulates two research problems: (1) What are the impact of oral presentation to the student’s apeaking ability? And (2) What are the factors that make the student difficult to do oral presentation? In this study, the researcher used qualitative research method for collecting data. To obtain the qualitative data, the researcher gave questionnaires for 25 students in the English Department of Tidar University.
READING AND ENGAGEMENT: IDENTITY-MAKING IN FIGURED WORLDS
Authors: Margono-Slamet Yosep B.
Published: May 2020

Literary texts create imaginary or figured worlds which might engage readers. Readers engaging in imaginary or figured worlds may develop new identities. Even though readers engage in the literary texts directly, they also have indirect relationship with authors in this process. This paper draws on some influential theories such as reader response, figured worlds, and identity theories. The interaction between reader and text is dialogic; the meaning of a text depends on the transaction between readers and the text they read. On the readers’ part, they always bring their history-in-person. This influences the meaning of the text. In the end, the act of reading is an act of identity making or remaking in figured worlds. Readers shape and reshape their identity in both real and imaginary worlds
大坝安全监测自动化的现状与展望
Authors: 王 树宝
Published: May 2020

现阶段中国已经进入大数据发展时代，人工智能、新概念技术也逐渐走向成熟，并在越来越多的行业中得到发展和应用，对经济和时代发展产生了极大影响，各个行业逐渐走向数据化、数字化，开启了智能化和自动化发展新常态。大坝安全监测就是受人工智能和自动化影响的重要领域之一，通过技术不断更新迭代，运用更多自动化、智能化监测技术提升整体安全监测自动化。
河长制的法制基础和实践问题
Authors: 何 书斌
Published: May 2020

随着中国经济的快速发展，国家越来越重视河湖的管理和保护，河长制在保护水资源、改善水环境、修复水生态和防治水污染中具有十分显著性的特点，是实现河湖长久治理的重要方式，也是中国目前依法治国理论的重要产物。因此，论文主要针对新阶段的河长制的法制基础和实践问题进行简要分析并提出合理化建议。
刍议无人机遥感技术在测绘工程测量中的应用
Authors: 魏 来
Published: May 2020

随着中国社会经济的快速发展，遥感技术逐渐被运用到各个领域中，为人们提供了极大的便利。在测绘工程测量工作中，工作人员利用无人机遥感技术，准确获取相应区域的图片、视频及信息资料，以此为测绘工作提供准确的数据，大大提高了测绘工程测量的工作效率，促进了中国测绘工程领域的发展与进步。论文简要阐述了无人机遥感技术在测绘工程测量中的应用发展情况，分析了无人机遥感技术在测绘工程测量中的应用优势，对无人机遥感技术在测绘工程测量中应用技术及其运用进行深入探究。
A STUDY ON FUTURE OF MOBILE BASED PAYMENT FOR GOVERNMENT SERVICES IN INDIA
Authors: Jaiswal Ashish
Published: May 2020

Digital India programme of Government of India has promoting and encouraging the usage of digital payments for the various goods and services being availed by the citizens. The Government wants to develop a Digitally Empowered economy through the cashless transactions. As far as government agencies are concerned, mobile based payment is a noteworthy development on various domains, because it is going to increase ease and productivity for both the agencies and citizens themselves. Citizens who are using the Government services are concerned of the privacy of the data and information. Government needs to evaluate the procedure from beginning to end to ensure it meets strict standards and keeps information private. Poor literacy levels are a problem with this technology. The mobile payment services have to be effective in terms of usability, cost, efficiency, interoperability and security for transactions of all categories of citizens. Mobile payments options needs to be available even on low end mobile handsets.
YBO3 Fosforunun Termolüminesans Dozimetrik Pikinin Kinetik Parametreleri
Authors: AKÇA Sibel
Published: May 2020

Bu çalışmanın amacı, katkısız itriyum borat (YBO3) fosforunun termolüminesans (TL) kinetik parametrelerini belirlemektir. Yanma reaksiyonu ile sentezlenen YBO3 fosforu pelet formuna getirilerek TL ölçümleri gerçekleştirilmiştir. Örnekler, 0,1-5 Gy aralığında beta dozuna maruz bırakılarak 2°C/s’lik sabit hızla oda sıcaklığından 500°C’ye kadar ısıtılmıştır. Örneğe ait TL ışıma eğrileri, hem farklı dozlar hem de farklı ısıtma hızları için elde edilmiştir. Elde edilen TL sinyalleri analiz edilerek 210°C’de merkezlenen TL dozimetrik pikinin tuzak parametrelerinin hesaplanması için mevcut pik şekli (PS), farklı ısıtma hızları (VHR) ve ışıma eğrisi ayrıştırma (GCD) metotları kullanılmıştır. Farklı dozlarda sergilenen TL pikine Chen’in PS metodu uygulandığında ortalama aktivasyon enerjisi (E) 0,847 eV, frekans faktörü (s) 107 s-1 mertebesinde bulunmuştur. İki farklı VHR metodu kullanılarak elde edilen E ve s değerleri, biri için sırasıyla 1,050 ± 0,05 eV ve 109 ± 103 s-1 mertebesinde diğeri için 0,890 eV ve 108 s-1 mertebesinde bulunmuştur. GCD metodu R-studio programının ‘‘tgcd’’ paketi kullanılarak uygulanmıştır. Ayrıştırma, 0,5 ve 5 Gy beta dozlarından elde edilen pik maksimuma uygulanmış ve 1. dereceden kinetiğe uyan iki pikten oluştuğu görülmüştür. Ayrıştırılmış piklerin (pik 1) E değerleri sırasıyla 0,889 ve 0,868 eV olarak bulunurken s değerleri ise her ikisi için de 108 s-1 mertebelerinde bulunmuştur.
Optimasi Produksi Bibit Tanaman Kentang (Solanum tuberosum) Kultivar Granola dengan Teknik Fotoautotrofik
Authors: Rai Sonya Putri , Wiendi Ni Made Armini
Published: May 2020

Tanaman yang ditumbuhkan dalam kondisi in vitro pada umumnya tidak melakukan fotosintesis, lapisan kutikula dan jaringan pembuluh antara akar dan pucuk tidak berkembang serta stomata belum berfungsi dengan baik sehingga sulit bertahan pada saat aklimatisasi. Teknik fotoautotrofik perlu dikembangkan untuk meningkatkan ketahanan planlet saat dipindahkan ke kondisi ex vitro. Penelitian ini bertujuan mempelajari respon pertumbuhan kentang kultivar Granola yang dikulturkan dengan sistem fotoautotrofik untuk menyediakan bibit kentang yang unggul dan bermutu. Penelitian dilaksanakan di Laboratorium Kultur Jaringan 2, analisis morfologi stomata dilakukan di Laboratorium Mikro Teknik, Departemen Agronomi dan Hortikultura, Fakultas Pertanian, Institut Pertanian Bogor. Penelitian dilakukan dari bulan November 2014 hingga April 2015. Penelitian ini terdiri dari dua percobaan terpisah. Percobaan pertama menggunakan bahan tanam buku tunggal, percobaan kedua menggunakan bahan tanam pucuk. Rancangan percobaan yang digunakan adalah Rancangan Kelompok Lengkap Teracak (RKLT) dua faktor, yaitu konsentrasi gula dan ventilasi. Pada percobaan pertama diperoleh bahwa peningkatan konsentrasi gula nyata meningkatkan jumlah daun dan buku tunas kentang (Solanum tuberosum). Interaksi gula yang rendah dan penambahan ventilasi menyebabkan peningkatan jumlah stomata dan kloroplas serta mengecilnya diameter stomata daun. Sebanyak 45 % planlet yang ditumbuhkan pada media dengan konsentrasi gula 25 gL-1 dengan ventilasi 1 serta 67 % planlet dari media gula 25 gL-1 dengan ventilasi 2 mampu bertahan selama aklimatisasi dan diduga dapat digunakan untuk produksi bibit. Pada percobaan 2 tidak terdapat planlet yang mampu bertahan pada tahap aklimatisasi.
THE INFLUENCE OF TEMPERATURE EMBRIONIC DEVELOPMENT EARLY STADIA OF YELLOW FIN TUNA LARVAE (Thunnus albacares)
Authors: Wardani Tiara Kusuma
Published: May 2020

The purpose of this study, to determine the effect of temperatura on embryonic development and early stadia larvae of yellow fin tuna (Thunnus albacares) and the level  abnormalities of the larvae. This research was carried out in a Large Marine Aquaculture Center And Hyacinth Fisheries Gondol. The container used is a 1 liter backer glass of 15 pieces. Egg density at each backer glass is 300 grains. The temperature treatment used is (240C±1), P2 (260C±1), P3 (280C±1), P4 (300C±1), P5 (320C±1). Parameters observed were egg hatchability, egg hatching time, larval abnormalities, absorption of egg yolk and larval length. Based on the result of the study showed that different temperature treatments were able to give a significant influence on the development of eggs and the time of hatching egg. The temperature treatment 260C was able to increase the hatchbility value by 40,7%, larvae abnormality value 15,8%, larvae length growth 5,48 mm compared to other temperature treatment. The best egg yolk absorption rate is shown at the temperature treatment of 240C, 260C, and 280C compared to the 300C and 320C temperature treatments.
Exploring bacterial pathogens and risk factors associated with the occurrence of navel ill in calves
Authors: RASSEL Md. Gulam Rabbany , MISHRA Pravin , RAHMAN Marzia , ALAM Md. Mahmudul
Published: May 2020

The study mentioned here was designed to investigate both bacterial pathogens and risk factors associated with the occurrence of naval ill in calves. A total of 350 calves diagnosed to have navel ill formed the population in our study. Incidence density reports representing the period between 2009 and 2018 were obtained from Veterinary Teaching Hospital (VTH), Bangladesh Agricultural University where information about age, sex, breed, seasonal effect was also included. Umbilical swab from each individual suffering from confirmed navel ill was collected for microbiological study. The occurrence of navel ill in the age of <30 days (n = 244, 69.71%) was noted higher compared to the age of ≥30 days (n = 106, 30.29%). Male calves were highly susceptible (n = 192, 54.86%) compared to females (n=158, 45.14%). In cross breed individuals, the occurrence was higher (n = 330, 94.29%) in regard of indigenous calves (n=20, 5.71%). The occurrence of the illness in summer (March-June) was more common (n = 159, 45.43%) in comparison to both rainy (n = 111, 31.71%) and winter (n = 80, 22.86%) seasons. In term of microbiological study, Staphylococcus aureus, E. coli and Proteus spp. were identified and isolated from the infected areas of the calves with the disease. In conclusion, navel ill occurred more commonly in male calves with the age of less than one month. The appearance of navel ill was noted to be more frequently in summer season (March-June) in cross breed calves. The results also demonstrated that the condition is mediated by mixed bacterial infection formed by gram-positive and gram-negative agents which induce the initial inflammation .
О методах улучшения растворимости антигельминтных лекарственных веществ
Authors: Халиков Салават Самадович , Душкин Александр Валерьевич
Published: May 2020

Большинство субстанций лекарственных веществ (ЛВ) плохо растворимы в воде и для повышения их эффективности приходится заведомо увеличивать дозировку, что создает проблемы не только экономического характера, но и повышает токсичность будущего препарата. Для решения таких проблем разработчиками препаратов предлагаются разнообразные лекарственные формы, что предполагает дополнительные финансовые расходы, усложнение технологии, увеличение времени на разработку и внедрение будущего препарата и т.д. Другим направлением для улучшения растворимости таких субстанций является разработка методов и технологий по получению твердых дисперсий этих субстанций с вспомогательными веществами (полимеры, диспергаторы, ПАВ и др.). В обзоре представлены результаты разработки и применения технологии механохимической модификации малорастворимых антигельминтных ЛВ. Суть технологии заключается в совместной механообработке субстанции ЛВ и полимера в измельчителях-активаторах с регулируемой энергонапряженностью. Эта технология одностадийна и исключает использование растворителей, процессы нагревания, испарения и пр. Полученные твердые дисперсии образуют супрамолекулярные системы, обладающие повышенной растворимостью, лучшей проникающей способностью, а также обладают высокой активностью при снижении нормы расхода активной субстанции.
Особенности определения бактериальных эндотоксинов в масляных растворах лекарственных средств
Authors: Шаповалова Ольга Владимировна , Неугодова Наталия Петровна , Сапожникова Галина Алексеевна
Published: May 2020

Рассмотрены вопросы, связанные с достоверной оценкой качества масляных растворов лекарственных средств по показателю «Бактериальные эндотоксины». Максимальному извлечению бактериальных эндотоксинов в жирорастворимых лекарственных средствах способствует интенсивное смешивание предварительно нагретых до 60 °C образцов с водой и последующее разделение 2 фаз с помощью центрифугирования при 2300 об/мин в течение 10 мин.
Комплексная оценка эффективности ремаксола у больных стеатогепатитом с гипераммониемией
Authors: Алексеенко С. А. , Колтунов А. С. , Агеева Е. А. , Сергеева А. Ю.
Published: May 2020

Изучена эффективность ремаксола у пациентов со стеатогепатитом различного генеза и гипераммониемией. Проанализированы результаты лечения 30 пациентов, получавших ремаксол внутривенно капельно со скоростью 40 – 60 кап/мин 400 мл 1 раз в сутки, курс 10 дней. Оценивали динамику (до начала лечения, через 5, 11 и 30 дней) общего самочувствия, когнитивных функций («Тест связи чисел»), уровня билирубина, трансаминаз, гамма-глутамилтранспептидазы и аммиака крови. Применение ремаксола сопровождалось улучшением клинико-лабораторных данных: уменьшалась выраженность астении и когнитивных нарушений по тесту связи чисел в 1,2 раза к 11 дню наблюдения до (50,77 ± 13,93) баллов. Выявлено улучшение функциональных печеночных показателей: снижение к 11 дню наблюдения средних значений уровня трансаминаз в 2,5 раза, гамма-глутамилтранспептидазы — в 1,9 раза, общего билирубина — в 1,7 раза, аммиака — в 1,8 раза, которое сохранялось до 30 дней от начала терапии (p ≤ 0,05). Корреляционный анализ выявил статистически значимую прямую корреляцию между уровнем аммиака, аспартатаминотрансферазы, общего билирубина, щелочной фосфатазы в крови и показателями теста связи чисел до начала терапии (ro1 = 0,64; ro2 = 0,39; ro3 = 0,72; ro4 = 0,49 при p < 0,05). При этом общее самочувствие пациентов нах дилось в статистически значимой обратной зависимости от показателей теста, уровней аммиака, аспартатаминотрасферазы, щелочной фосфатазы, гамма-глутамилтранспептидазы и общего билирубина в крови (ro1 = – 0,56; ro2 = – 0,46; ro3 = – 0,58; ro4 = – 0,56; ro5 = – 0,6; ro6 = – 0,38 при p < 0,05). Полученные результаты свидетельствуют об эффективности ремаксола у пациентов со стеатогепатитом различной этиологии с гипер-аммониемией, что, наряду с хорошей переносимостью препарата, позволяет рекомендовать его включение в схемы лечения.
О влиянии нового производного пиримидина PIR-4 на концентрацию маркеров внешнего и внутреннего путей апоптоза в условиях экспериментальной церебральной ишемии
Authors: Воронков Андрей Владиславович , Шабанова Наталья Борисовна
Published: May 2020

Исследовано антиапоптотическое действие нового производного пиримидина под шифром PIR-4 в условиях экспериментальной фокальной церебральной ишемии у крыс линии Вистар, разделенных на 5 групп (n = 10). В первую группу включены ложнооперированные особи, вторая группа — крысы негативного контроля, получавшие взвесь очищенной воды и твина-80. Третья и четвертая группы представлены животными, получавшими препараты сравнения кавинтон (3,2 мг/кг) и глиатилин (60 мг/кг), соответственно. Пятой группе крыс вводили соединение PIR-4. Все соединения вводили сразу после моделирования ишемии и в течение 3 сут ежедневно. Модель фокальной ишемии мозга — окклюзия левой средней мозговой артерии (наркоз — хлоралгидрат, 350 мг/кг). В ходе проведенного исследования установлено, что на фоне моделируемой патологии возрастает концентрация фактора некроза опухоли (TNF-α), фактора, индуцирующего апоптоз (AIF), p53-зависимого модулятора апоптоза (PUMA), снижается уровень Jun-N-концевой киназы (JNK). Препараты сравнения кавинтон и глиатилин корректировали возникшие изменения, препятствуя развитию внешнего и внутреннего путей апоптоза. На фоне получения крысами вещества PIR-4 также уменьшал концентрацию маркеров каспаза-зависимого и каспаза-независимого путей апоптоза, при этом по антиапоптотическому эффекту, превосходя кавинтон и не уступая глиатилину.
Getting stuck in social isolation: Solitude inertia and depressive symptoms
Authors: Elmer Timon , Geschwind Nicole , Peeters Frenk , Wichers M. , Bringmann Laura Francina
Published: May 2020

Social isolation and depression are tightly linked and can reinforce each other in a vicious cycle. Yet, the antecedents of this complex cycle are not well understood. To date, little is known about how the dynamics of social isolation in daily life (i.e., solitude) play a role in this cycle. To investigate these complex dynamics, we introduce the concept of solitude inertia, which captures individuals’ tendencies to remain in social states of solitude. We argue that, although short-term solitude can have both positive and negative effects on individuals’ depressive symptoms, prolonged states of solitude (i.e., high solitude inertia) are detrimental. At the same time, individuals with depression might be more vulnerable to ‘get stuck’ in solitude. In this study, we tease apart the bidirectional relationship between solitude inertia and depressive symptoms. We use data from the MindMaastricht study in which 129 individuals with residual depressive symptoms participated in two experience sampling assessments phases (T1 and T2) that were eight weeks apart (Nobs = 11,558). Using logistic multilevel models, we find that higher levels of depressive symptoms are related to higher solitude inertia. We further show that depressive symptoms at T1 are not predictive of solitude inertia at T2. However, solitude inertia at T1 was predictive of depressive symptoms eight weeks later (T2) in a linear regression analysis. This study introduces and highlights the role of solitude inertia as a potential intervention target in social isolation and depression dynamics.
Linguistic Overhypotheses in Category Learning: Explaining the Label Advantage Effect
Authors: Ivanova Anna Aleksandrovna , Hofer Matthias
Published: May 2020

When learning to partition the world into categories, people rely on a set of assumptions (overhypotheses) about possible category structures. Here we propose that the nature of these overhypotheses depends on the presence of a verbal label associated with a given category. We describe a computational model that demonstrates how labels can either accelerate or hinder category learning, depending on whether or not the prior beliefs imposed by their presence align with the true category structure. This account provides an explanation for the phenomena described in prior experimental work (Lupyan, Rakison, & McClelland, 2007; Brojde, Porter, & Colunga, 2011) that have remained unexplained by other models. Based on these results, we argue that the overhypothesis theory of label effects provides a way to formalize and quantify the effect of language on category learning and to develop a more precise delineation between linguistic and non-linguistic thought.
Obat Aborsi Malang ( Ampuh ) 082314597755 Klinik Jual Obat Penggugur Kandungan Di Malang
Authors: okeybidan
Published: May 2020

Jual Obat Aborsi Malang, Jual Cytotec Banyuwangi, Klinik Aborsi Di Malang, Obat Pelancar Haid Malang, Obat Penggugur Kandungan Malang, Obat Telat Datang Bulan MalangOBAT ABORSI MALANG —  OBAT ABORSI AMPUH —  JUAL OBAT PENGGUGUR KANDUNGAN TUNTASObat Aborsi Ampuh 0823 1459 7755 | Jual Obat Aborsi | Obat Aborsi Cytotec | Obat Telat Bulan | Obat Pelancar Haid | Obat Penggugur KandunganAPOTIK : Kami Jual Obat Aborsi Ampuh Hub : 0823 1459 7755 | Jual Obat Aborsi Aman | Obat Penggugur Kandungan Cytotec Ampuh | Obat Pelancar Haid Tuntas. Dengan harga yang bisa anda pilih sesuai usia kandungan anda. Obat yang kami jual ampuh dan tuntas untuk menunda kehamilan atau proses aborsi untuk usia kandungan 1–6 BulanApa itu Aborsi ?“Abortion Adalah dengan membendung hormon yang di perlukan untuk mempertahankan kehamilan yaitu hormon progesterone, karena hormon ini di bendung, maka jalur kehamilan mulai membuka dan leher rahim menjadi melunak, sehingga mulai mengeluarkan darah yang merupakan tanda bahwa obat telah bekerja (maksimal 1 jam sejak obat diminum) darah inilah yang kemudian menjadi pertanda bahwa pasien telah mengalami menstruasinya, sehingga secara otomatis kandungan di dalamnya telah hilang dengan sendirinya 100% berhasil…linkedin.com/showcase/jual-obat-aborsi-di-banyuwangi-cytotec-misoprostol-asliLalu Anda Kirimkan SMS Ke Nomer Kami___________________________________.:: HUBUNGI ::..:: PEMESANAN LEBIH NYAMAN VIA SMS ::.Di No. Hp / WA : 0823 1459 7755Call : 082314597755
Tempat Klinik Obat Aborsi Cytotec Madiun 082242388712 Jual Obat Penggugur Kandungan Di Madiun
Authors: leopribad
Published: May 2020

Jual Obat Aborsi Madiun, Jual Cytotec Madiun, Klinik Aborsi Di Madiun, Obat Pelancar Haid Madiun, Obat Penggugur Kandungan Madiun, Obat Telat Datang Bulan MadiunOBAT ABORSI CYTOTEC  —  OBAT ABORSI AMPUH —  JUAL OBAT PENGGUGUR KANDUNGAN TUNTASObat Aborsi Ampuh 0822 4238 8712 | Jual Obat Aborsi | Obat Aborsi Cytotec | Obat Telat Bulan | Obat Pelancar Haid | Obat Penggugur KandunganAPOTIK : Kami Jual Obat Aborsi Ampuh Hub : 0822 4238 8712 | Jual Obat Aborsi Aman | Obat Penggugur Kandungan Cytotec Ampuh | Obat Pelancar Haid Tuntas. Dengan harga yang bisa anda pilih sesuai usia kandungan anda. Obat yang kami jual ampuh dan tuntas untuk menunda kehamilan atau proses aborsi untuk usia kandungan 1–6 BulanApa itu Aborsi ?“Abortion Adalah dengan membendung hormon yang di perlukan untuk mempertahankan kehamilan yaitu hormon progesterone, karena hormon ini di bendung, maka jalur kehamilan mulai membuka dan leher rahim menjadi melunak, sehingga mulai mengeluarkan darah yang merupakan tanda bahwa obat telah bekerja (maksimal 1 jam sejak obat diminum) darah inilah yang kemudian menjadi pertanda bahwa pasien telah mengalami menstruasinya, sehingga secara otomatis kandungan di dalamnya telah hilang dengan sendirinya 100% berhasil…Lalu Anda Kirimkan SMS Ke Nomer Kami___________________________________.:: HUBUNGI ::..:: PEMESANAN LEBIH NYAMAN VIA SMS ::.Di No. Hp / WA : 0822 4238 8712
Tempat Klinik Obat Aborsi Cytotec Palembang 082242388712 Jual Obat Penggugur Kandungan Di Palembang
Authors: hellobidan
Published: May 2020

Jual Obat Aborsi Palembang, Jual Cytotec Palembang, Klinik Aborsi Di PalembangOBAT ABORSI PALEMBANG —  OBAT ABORSI AMPUH —  JUAL OBAT PENGGUGUR KANDUNGAN TUNTASObat Aborsi Ampuh 0822 4238 8712 | Jual Obat Aborsi | Obat Aborsi Cytotec | Obat Telat Bulan | Obat Pelancar Haid | Obat Penggugur KandunganAPOTIK : Kami Jual Obat Aborsi Ampuh Hub : 0822 4238 8712 | Jual Obat Aborsi Aman | Obat Penggugur Kandungan Cytotec Ampuh | Obat Pelancar Haid Tuntas. Dengan harga yang bisa anda pilih sesuai usia kandungan anda. Obat yang kami jual ampuh dan tuntas untuk menunda kehamilan atau proses aborsi untuk usia kandungan 1–6 BulanJual Obat Aborsi Cytotec Misoprostol Asli Usia 1 2 3 4 5 6 Bulan 100% TuntasKami jual Obat Penggugur Kandungan Ampuh untuk kehamilan dari umur janin 1 2 3 4 5 6 7 Bulan, Obat Penggugur Kandungan Asli Cytotec Misoprostol Pfizer Di Produksi Oleh Dokter Terkemuka Di AMERIKA PT PFIZER USA.Apa itu Aborsi ?“Abortion Adalah dengan membendung hormon yang di perlukan untuk mempertahankan kehamilan yaitu hormon progesterone, karena hormon ini di bendung, maka jalur kehamilan mulai membuka dan leher rahim menjadi melunak, sehingga mulai mengeluarkan darah yang merupakan tanda bahwa obat telah bekerja (maksimal 1 jam sejak obat diminum) darah inilah yang kemudian menjadi pertanda bahwa pasien telah mengalami menstruasinya, sehingga secara otomatis kandungan di dalamnya telah hilang dengan sendirinya 100% berhasil…* Paket Obat Telat Bulan — Obat Aborsi Standar 90% TingkatKeberhasilan* Paket Obat Telat Bulan — Obat Aborsi Tuntas 99% Tingkat Keberhasilanwebsite resmi : klinikobatherbal.comLalu Anda Kirimkan SMS Ke Nomer Kami___________________________________.:: HUBUNGI ::..:: PEMESANAN LEBIH NYAMAN VIA SMS ::.Di No. Hp / WA : 0822 4238 8712Call : 082242388712
Diffuse alveolar haemorrhage – Is it an unusual or unlooked presentation of Fat Embolism Syndrome? A Case report and review of literature
Authors: Maskey Dipesh
Published: May 2020

Fat embolism syndrome (FES) is a constellation of clinical symptoms characterized by a triad of respiratory insufficiency, altered sensorium and petechiae occurring after orthopaedic trauma or following surgical manipulation of long bones and spine. The diagnosis is based on clinical presentation and excluding other possible conditions. Beside histopathology, none of the investigations such as fat macroglobinuria in urine or lipid laden macrophages in bronchoalveolar lavage (BAL) is 100% specific. At times FES can present with atypical presentation such as intra alveolar haemorrhage and only high index of suspicion can help in making diagnosis.
Dikotomi Keruangan Wilayah: Karakteristik Wilayah dan Daya Saing Daerah Provinsi Jawa Timur
Authors: Rahmah Ihdiny Mauhiya Miftahar
Published: May 2020

Pembangunan daerah dilaksanakan berdasarkan potensi masing-masing daerah. Pembangunan daerah diharapkan dapat meningkatkan kualitas hidup masyarakat. Namun, implementasi pembangunan daerah masih belum merata di seluruh wilayahnya. Dalam tulisan ini, penulis bertujuan untuk mengidentifikasi perkembangan Provinsi Jawa Timur dengan pendekatan spasial dan non-spasial untuk mengetahui karakteristik secara lebih rinci. Untuk analisis spasial, dilakukan melalui analisis wwwwxwdikotomi sesuai dengan kondisi geografis Provinsi Jawa Timur di mana sebagian wilayahnya terletak di Pulau Jawa dan sebagian lagi terletak di Pulau Madura dan beberapa pulau di sekitarnya. Di sisi lain, analisis juga dilakukan pada aspek non-spasial yang dilakukan dengan dikotomi antara daerah maju dan terbelakang. Sebagaimana disebutkan dalam Peraturan Presiden Republik Indonesia Nomor 131 Tahun 2015 tentang Penentuan Daerah Tertinggal 2015-2019, ada 4 kabupaten yang masih termasuk dalam daerah Tertinggal. Berdasarkan analisis spasial dan non-spasial yang mengidentifikasi karakter masing-masing daerah, penulis telah mengembangkan beberapa rekomendasi strategi untuk masing-masing daerah. Strategi-strategi ini termasuk meningkatkan daya saing melalui peningkatan infrastruktur dan kualitas sumber daya manusia untuk mencapai pembangunan inklusif.
Tradisionalitas dan Modernitas Dikotomi Perkembangan Wilayah Pesisir Kabupaten Gunungkidul
Authors: Nurzaman Arie
Published: May 2020

Pola aktivitas dan penggunaan ruang dipengaruhi oleh banyak faktor, termasuk ekonomi, sosial, budaya, atau sejarah. Daerah pedesaan yang umumnya didominasi oleh daerah tertinggal menjadi korban eksploitasi manusia dalam hal pemanfaatan ruang, termasuk wilayah pesisir. Oleh karena itu, pemanfaatan dan pengembangan wilayah pesisir dan masyarakat yang tinggal di kawasan tersebut membutuhkan pendekatan yang tepat. Dikotomi ruang perlu dipahami sebagai aspek pengembangan wilayah pesisir itu sendiri. Makalah ini bertujuan untuk menilai pola pemanfaatan ruang, dikotomi antara aspek tradisional dan modern dalam pemanfaatan ruang, serta kemungkinan strategi dan kebijakan pengembangan pemerintah wilayah pesisir di Kabupaten Gunungkidul. Metode ini merupakan kombinasi dari metode kuantitatif yang dilaksanakan dengan meninjau peta dan analisis data sekunder untuk melihat tren perkembangan dalam periode tertentu, sedangkan metode kualitatif dilakukan untuk memperkuat hipotesis dan untuk memahami analisis lebih lanjut dari pendekatan kuantitatif.Dikotomi ruang dijabarkan dalam konteks spasial dan pemanfaatan. Konteks spasial dibagi menjadi wilayah inti (ibukota kecamatan) dan pinggiran (wilayah pesisir), sedangkan dalam konteks pemanfaatan ruang, dibedakan menjadi penggunaan tradisional dan modern. Analisis dikotomi melalui penggambaran kuadran memberikan gambaran tentang potensi pembangunan daerah, ruang lingkup pembangunan tidak hanya sebagian tetapi juga secara spasial. Pengembangan Jaringan Jalan Nasional Jawa Selatan (JJLS) dan pengembangan sektor pariwisata adalah dua faktor utama dalam pembangunan daerah, sehingga kebijakan publik sebagai implementasi dari intervensi pemerintah setidaknya harus mempertimbangkan sektor spesifik yang akan ditangani, prioritas pembangunan seperti skala dan pendekatan, dan tingkat perkembangan.Kata kunci: dikotomi; tradisional; modern; Gunungkidul; wilayah pesisir
Une analyse engagée de la professionnalisation des pratiques d’évaluation
Authors: Gauthier Benoît
Published: May 2020

Abstract: Despite a great deal of discussion about the notion of professionalizing evaluation practice around the world, many associated concepts are not clearly defined. This practice note provides operational definitions of the concepts of profession, professionalism, professional and professionalization, and presents methodology designed to reflect on the ins and outs of a national process of professionalization. In conclusion, the author analyzes the prospects for the professionalization of the practice of evaluation at an international level.
PELINDUNGAN TERHADAP INVENTOR BERKAITAN DENGAN PUBLIKASI DAN HUBUNGAN DINAS PASCA BERLAKUNYA UNDANG-UNDANG NOMOR 13 TAHUN 2016 TENTANG PATEN
Authors: Sudjana
Published: May 2020

Kajian ini menjelaskan tentang subyek hukum paten yaitu inventor atau pemegang hak, inventor terkait dengan publikasi di Perguruan Tinggi atau lembaga ilmiah nasional (new invention dan inventive step), dan inventor dalam hubungan dinas. Hasil kajian menunjukan bahwa: (1). Subyek hukum paten menurut Undang-Undang Nomor 14 Tahun 2001 adalah orang perorangan, sedangkan Undang-Undang Nomor 13 Tahun 2016 merumuskan inventor lebih luas karena meliputi orang perorangan dan badan hukum. Namun, istilah  “badan hukum” membawa konsekuensi   pemohon yang berstatus “badan” belum mendapat pelindungan sebelum berubah menjadi “badan hukum;” (2). Inventor terkait publikasi di Perguruan Tinggi atau lembaga ilmiah nasional mendapat pelindungan melalui pengecualian terhadap aspek kebaruan. Norma tersebut akan mendorong civitas akademika (dosen atau mahasiswa) untuk melakukan penelitian  terhadap “hal-hal baru”  baik dalam rangka studi sarjana  atau pascasarjana maupun pengembangan IPTEK yang “berpotensi menghasilan Paten”  karena  selain  memenuhi “tugas pokoknya” juga mendapat insentif “hak paten” meskipun telah diumumkan untuk kepentingan di lingkungan tersebut; (3).Inventor dalam hubungan dinas (Aparatur Sipil Negara) mendapat pelindungan karena memiliki hak ekonomi, bahkan apabila pemerintah tidak melaksanakan paten tersebut, inventor berdasarkan  persetujuan Pemegang Paten dapat melaksanakan Paten dengan pihak ketiga dan selain Pemegang Paten, Inventor memperoleh royalti dari pihak ketiga yang mendapatkan manfaat ekonomi dari komersialisasi Paten tersebut serta tidak menghapuskan hak Inventor untuk tetap dicantumkan namanya dalam sertifikat Paten.
An Objective and Reliable Method for Identifying Sarcopenia in Lumbar Spine Surgery Patients: Using Morphometric Measurements on Computed Tomography Imaging
Authors: Tomov Marko , Alvi Mohammed Ali , Elminawy Mohamed , Currier Bradford , Yaszemski Michael , Nassr Ahmad , Huddleston Paul , Sebastian Arjun , Bydon Mohamad , Freedman Brett
Published: May 2020

Study Design: A retrospective observational study.Purpose: Establish a quantifiable and reproducible measure of sarcopenia in patients undergoing lumbar spine surgery based on morphometric measurements from readily available preoperative computed tomography (CT) imaging. Overview of Literature: Sarcopenia—the loss of skeletal muscle mass—has been linked with poor outcomes in several surgical disciplines; however, a reliable and quantifiable measure of sarcopenia for future assessment of outcomes in spinal surgery patients has not been established.Methods: A cohort of 90 lumbar spine fusion patients were compared with 295 young, healthy patients obtained from a trauma da¬tabase. Cross-sectional vertebral body (VB) area, as well as the areas of the psoas and paravertebral muscles at mid-point of pedicles at L3 and L4 for both cohorts, was measured using axial CT imaging. Total muscle area-to-VB area ratio was calculated along with intraclass correlation coefficients for interobserver and intraobserver reliability. Finally, T-scores were calculated to help identify those patients with considerably diminished muscle-to-VB area ratios.Results: Both muscle mass and VB areas were considerably larger in males compared with those in females, and the ratio of these two measures was not enough to account for large differences. Thus, a gender-based comparison was made between spine patients and healthy control patients to establish T-scores that would help identify those patients with sarcopenia. The ratio for paravertebral muscle area-to-VB area at the L4 level was the only measure with good interobserver reliability, whereas the other three of the four ratios were moderate. All measurements had excellent correlations for intraobserver reliability.Conclusions: We postulate that a patient with a T-score <−1 for total paravertebral muscle area-to-VB area ratio at the L4 level is the most reliable method of all our measurements that can be used to diagnose a patient undergoing lumbar spine surgery with sarcopenia.
"España ante la CEE: del Acta Única al Tratado de Maastricht" (Recensión)
Authors: Camacho Laraña Ildefonso
Published: May 2020

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Cost of Producing Fresh Market Grapefruit in Indian River in 2018/19
Authors: Singerman Ariel
Published: May 2020

This 4-page fact sheet written by Ariel Singerman and published by the UF/IFAS Food and Resource Economics Department presents the cost of production per acre for growing fresh grapefruit in the Indian River region during 2018/19. Estimates reflect costs and cultural practices for a panel of growers, particularly important information at this time because, since citrus greening (HLB) was found, growers have been modifying their practices from year to year in an attempt to cope with the disease. https://edis.ifas.ufl.edu/fe1078
Red Heart Disease in Pines Caused by Porodaedalea (Phellinus) pini in Florida
Authors: Huang Yin-Tse , Eickwort Jeffrey , Hulcr Jiri
Published: May 2020

All pine species in Florida are susceptible to red heart disease. The disease can decrease timber value and weaken trees, making them threats to people and property. In forests, however, the same disease can be beneficial to cavity-nesting animals like red-cockaded woodpeckers. This 3-page fact sheet written by Yin-Tse Huang, Jeffrey Eickwort, and Jiri Hulcr and published by the UF/IFAS School of Forest Resources and Conservation describes the disease and provides some tips to manage it in areas where it could cause problems for people.http://edis.ifas.ufl.edu/fr425