bluuebunny/crossref_metadata_2025 huggingface dataset:
Barcelona y la música de moda. De lo finisecular decimonónico a comienzos del siglo XX (nuevos bailables y llegada del jazz). El caso de Clifton Worsley (*1873; †1925). Parte I. Una biografía en su contexto
Authors: Ezquerro Esteban Antonio , Ezquerro Guerrero Cinta
Published: January 2019

En el nuevo contexto internacional (urbano, industrializado, despreocupado y alegre) que se sitúa entre la Exposición Universal de Barcelona en 1888 y la Exposición Internacional de Barcelona de 1929, la Ciudad Condal vivió momentos de un auge cultural, artístico y musical, hasta entonces desconocidos e insospechados. Beneficiada por una burguesía pujante y crecientemente acaudalada, y espoleada por las novedades llegadas desde el exterior hasta su activo y rico puerto marítimo, la ciudadanía barcelonesa expresó, extrovertidamente, unas ansias de vivir, de apostar por la modernidad y de competir con otras ciudades coetáneamente emergentes (París, Nueva York, Londres o Milán), que se tradujeron en unas nuevas músicas “de consumo” y entretenimiento, para amenizar bailes de sociedad y actividades de ocio y deportivas, testigos de los “nuevos tiempos” (la “Belle Époque”). En ese contexto, en el que arquitectos (L. Domènech i Montaner, J. Puig i Cadafalch, A. Gaudí), pintores (R. Casas, S. Rusiñol, M. Utrillo, P. Picasso), poetas (J. Maragall, J. Verdaguer, E. Marquina) y músicos (F. Pedrell, E. Granados, P. Casals, E. Morera, F. Mompou) compartían públicos y escenarios, surgió la figura, peculiar, controvertida, y hoy prácticamente desconocida, de un músico, pianista, editor y comerciante, Pedro Astort Ribas, que iba a utilizar un nombre artístico, como reclamo comercial internacional, Clifton Worsley, para darse a conocer mundialmente como el creador del “vals-boston”. Una fama rápida, que se acrecentó en breve gracias a la difusión aportada por las nuevas tecnologías entonces en boga: una nueva producción y distribución “industrial” de partituras, los rollos de pianola, discos de vinilo y otras grabaciones mecánicas de audio y, muy particularmente, la radio.
Optimized Method for Reticulocyte Counting: Simple, Accurate, and Comparable to Flow Cytometry
Authors: Moradabadi MSc Alireza , MSc Morteza Khaleghi , PhD Maryam Shahdoost , PhD Alireza Farsinejad
Published: January 2019

Background: Reticulocytes are immature red blood cells with RNA, spending the final stages of their maturation in the peripheral blood. The number of reticulocytes in the peripheral blood is the salient evidence of the effectiveness of bone marrow to produce red blood cells. Currently, reticulocyte count is done manually or automatically in clinical laboratories. Difficulties and limitations of these approaches, including imprecision, poor reproducibility and laboriousness are clear. This study used modification in manually staining method to achieve better counting.
Materials and Methods: The reticulocyte counts of 30 samples were obtained from patients referred to Afzalipour hospital in Kerman, Iran. The patients aged between 0-3 years old (median age= 1.4 years). Samples were investigated for reticulocyte count by three different methods, including conventional, modified, and flow cytometry methods. Modified staining method is used in the optimized method which helps operator to countg reticulocyte better than conventional method.
Results: Analysis of the results showed a reasonable agreement. Sphericity assumption was checked by Kolmogorov-Smirnov and Mouchley analyses. Repeated measurement analysis was performed using Greenhouse-Geisser correction (F=16.6, df=1.105) according to pairwise comparisons with Bonferroni adjustment. Mean differences for flow cytometry, optimized and common methods were 3.88, 3.59, and 2.46 were significant at the 0.05 level, respectively.
Conclusion: The proposed optimized method was simple method, highly reliable, and comparable to flow cytometry. Due to the ease of implementation, this method did not need specialized training or the use of complex devices so it is affordable.
Key words: Blood Stains, Flow Cytometry, Reticulocyte, Reticulocyte Count, Staining and Labeling
Frequency and Risk Factors of Red Blood Cell Alloimmunization in Thalassemia Major Patients in Markazi province
Authors: MD Aziz Eghbali , MD Roghaieh.Rahimi-Afzal , MD Sarvenaz Mehrabi , MD Seyed Amir Sanatkar , MD Morteza Mousavi-Hasanzadeh
Published: January 2019

Background: Thalassemia is one of the most common genetic disorders throughout the world. Blood transfusion plays an important role in the treatment of thalassemia but it leads to numerous complications such as iron overload and alloimmunization. This study evaluated the frequency and risk factors associated with alloimmunization in thalassemia major patients living in Markazi province, Iran.
Materials and Methods: In this descriptive study, 48 thalassemia major patients who underwent blood transfusion at Amirkabir hospital were included. Patients' demographic data were recorded using a questionnaire. In order to perform alloimmunization screening and autoantibody assessment, patients were referred to Tehran Blood Transfusion Organization Laboratory.
Results: The current study was performed on 48 patients with thalassemia major,. The mean age of patients was 12.5 ± 8.3 years. Among patients 26 (54.16%) were male and 22 (45.83%) were female, 13 patients (27.08%) had alloantibodies. Among 48 patients, 19 (39.58%) had undergone splenectomy. The patients' age of the first blood transfusion ranged from 1 month to 14 months      and the mean age of the first blood transfusion was 9.5 ± 7.08 months. The blood transfusion intervals in patients were from 21 days to 40 days and the blood volume received at each transfusion session was 10-15 cc/kg of the body weight. In the current study, the data analysis indicated no significant correlation between alloantibodies and RH phenotype (P=0.43), patients' gender (P=0.9), or blood groups (P=0.4); whereas, a significant correlation was found between alloantibodies and splenectomy (P=0.02) as an increase in the prevalence of alloantibodies was reported in splenectomised patients.
Conclusion: No significant difference was found between the patients with and without alloantibodies in terms of the prevalence of Rh phenotype, gender, and blood groups. However, there was a significant difference between the patients with and without alloantibodies in terms of splenectomy.
Key words: Allo-immunization, Risk factors, Thalassemia major
American Plans to Build Democracy in the Middle East After 9/11: the Case of Iraq
Authors: Waśko-Owsiejczuk Ewelina
Published: January 2019

The “Freedom Agenda” of President George W. Bush for the Middle East assumed that the liberation of Iraq from the dictatorship of Saddam Hussein and the start of political change would trigger the process of democratization of the entire region. Encouraged by financial and economic support, Arab countries should have been willing to implement political and educational support, which would lead to the creation of civil society and grass-roots political changes initiated by society itself. A number of mistakes made by the Bush administration in Iraq has not only caused the mission of the democratization of Iraq to be a failure, but also influenced the situation that today Iraq is closer to being a failed state than a democracy.
Iranian–Turkish Relations in a Changing Middle East
Authors: Gasparetto Alberto
Published: January 2019

After the outbreak of the Arab Spring and, above all, the intensification of the Syrian crisis with Ankara starting to engage in a political confrontation with Assad’s Syria, Tehran tried to exploit its historic strategic alliance with Damascus in a search for projecting its influence abroad. As Turkey has been facing more and more hardships and experiencing political isolation, Iran seemed to be more comfortable with its external environment, ben­efiting from a convergence of interests with Russia. However, the advent of ISIS created further disarray in the region, presenting opportunities for countries to cooperate especially for Erdogan’s new Turkey which was still focused on fighting Kurds.
The potential and prospects of the quantitative phase imaging (QPI) diagnostic technology in obstetrics and gynecology
Authors: Lifenko R. A. , Popova O. S. , Topuzov A. G. , Zverzhhovsky V. D.
Published: January 2019

Rationale:An important role of immunological factors in the endometriosis pathophysiology allows for their consideration as diagnostic and prognostic disease markers. A promising approach to the diagnosis of immunological abnormalities is based on the non-invasive cell diagnostic technology of quantitative phase imaging (QPI), with underlying principles of laser interferometry and holography.

Aim:To assess the QPI potential to identify diagnostic criteria for cell immunity abnormalities in female patients with external endometriosis.

Materials and methods:We performed a quantitative assessment of the cytotoxic potential of peripheral blood lymphocytes from 22 patients with endometrioid ovarian cysts (mean age, 27.1 ± 3.4 years), 20 patients with uterine leiomyoma (mean age, 29.3 ± 4.1 years) and 20 health non-pregnant women of child-bearing age (mean age, 28.7 ± 3.6 years). We used the non-invasive QPI technique with the module for phase interference microscopy of the Russian hardand software complex Bioni (Westtrade Ltd., Russia).

Results:We studied phase interference pictures of native lymphocytes to identify morphological and densitometry characteristics for CD4+ и CD8+ cells. Two groups of cells were identified in the cytotoxic lymphocyte population, which differed in their values of the phase thickness (Hcyt) and the area of cytoplasm adjacent to the membrane and containing the perforin granules (Scyt). It was found, that in the healthy controls the proportion of perforin-positive cytotoxic CD8+ lymphocytes was 37.1 ± 5.15%, in the patients with endometriosis 29.8 ± 6.34%, and in those with uterine leiomyoma 42.6 ± 5.89%.

Discussion:Assessment of the lymphocyte cytotoxic potential by quantitative determination of cells containing perforin granules may be an important diagnostic and prognostic criterion of the disease course.

Conclusion:Studies of the intracellular structures of lymphocytes by non-invasive and non-reagent technology QPI allows not only for a detailed evaluation of pathophysiological mechanisms of immune competent cell transformation in the course of a pathological process, but also gives future directions for development of new approaches to functional assessment of the immune system based on the results obtained.
Environmental Health Risk Assessment of NO2 Ambient Level and Toll Collectors Officer‘S Health Complaints
Authors: Wulaningtyas Febri Ayu
Published: January 2019

Nowadays NO2 ambient level has been increasing in year to year. Pollutant level which has over level from the threshold limit will give some of bad effects to environment and human health. The aim of this study was to measure the environmental health risk assessment of NO2 ambient level and toll collectors officer ‘s health complaints at Toll gate of Dupak 1, Surabaya. This was descriptive study with cross sectional design. Interview was done to 17 respondents who met the conclusion criteria to know respondent’s health complaints. Independent variables were NO2 level, sex, age, weight, length of work in a day and work period. Where as dependent variabel was toll collectors officer’s of Toll gate of Dupak 1 Surabaya health complaints, such as: headache, eyes irritation, red eyes, hard to breath and cough. Result shown that respondent with 62 weight average were not safe work in Toll gate of Dupak 1 if the air velocity was 0.83 m3/ hour, in 8 hour/day, average of time in 350 days/year for next 30 years if NO2 level had maximal concentration 0.1183 ppm (RQ > 1). The majority of health complaints were cough 82.3%, red eyes 70.5%, eyes irritation 64.7%, headache 53%, and hard to breath 47%. However risk quotient of NO2 exposure was not safe for respondent with pollutants level appropriate to the measurement result and should have preventive action like as consume vitamin C and E and use N95 and regulations for using masker and not smoking while work have to applied strictly.
Identification of CO Exposure, Habits, COHb Blood and Worker’s Health Complaints on Basement Waterplace Apartment, Surabaya
Authors: Dewanti Intan Retno
Published: January 2019

Carbon monoxide (CO) is a silent killer because it is tasteless, colorless, odorless, and causes of death. In the basement, pollution level from vehicle engines combustion is higher than in the ambient air. Workers in the basement potentially expose to CO that trapped while they were working. CO inhaled will form COHb on the blood. This study aims to identify CO exposure, worker habits, COHb blood, and health complaints during their working time in the basement of apartment Waterplace Surabaya. This research was a descriptive with cross-sectional design and used purposive sampling technique with 20 respondents. Data which were collected through observation and interviews. The result showed that CO measurement was below 25 ppm standard. Most characteristics of workers were male (80.0%), 21–29 years old (55.0%), working time for ≤ 12 months (55.0%) and working hours for 12 hours (55.0%). The worker’s habits mostly were smoking (80.0%), regularly consume fruit (55.0%) and vegetables (60.0%). The majority (90.0%) COHb level was above the 3.5% standard. Health worker complaints were dizziness (80.0%), impaired concentration (60.0%) and tired (55.0%) while their working time. Workers that smoking, eating fruits, and vegetables were having a blood COHb levels higher. It was concluded that the levels of CO gas below the standards while blood COHb above the standards. It was suggested to reduce smoking, to start a healthier lifestyle, and to use masker while their working time.
The Processing of Hazardous and Toxic Hospital Solid Waste in Dr. Soetomo Hospital Surabaya
Authors: Purwanti Alvionita Ajeng
Published: January 2019

The increasing number of hospital, increases medical waste in Indonesia. Medical waste is categorized as hazardous and toxic waste as mentioned in Appendix I of Government Regulation number 101 in 2014. The hazardous and toxic waste management in hospital is necessary because if  it is not managed properly can cause injury, environmental pollution, and nosocomial disease. Hazardous and toxic hospital waste management can minimize the effect of it. The purpose of this study was to identify the flow of hazardous and toxic waste management in RSUD Dr. Soetomo according to the regulations. The research type was descriptive observational using secondary data from the installation of environmental sanitation. Data was compared to the Minister of Environment and Forestry Regulation No. P.56 in 2015 about Technical Procedures and Technical Requirements for the Hazardous and Toxic Waste’ s Management from Health Service Facilities. The results showed that the management of hazardous and toxic waste in RSUD Dr. Soetomo was fulfill the requirements in the regulation of the Minister of Environment and Forestry No. P.56 of 2015 from the reduction and segregation, storage, transportation and treatment of hazardous and toxic waste.
Relationship between House Sanitation and Number of Bacterial in Bed Room with Pneumonia Case of Children Under Five Years Old in Kenjeran Sub District Surabaya
Authors: Rahmawati Fitria Nur
Published: January 2019

The number of  pneumonia  cases in children under five years found in Surabaya city in 2016  was 3,925 cases (40.89%). The number of  pneumonia  cases in children under five years in Kenjeran sub district was highers with 232 cases. This study was purposed to analyze the relationship between house sanitation and airborne bacterial number with pneumonia cases in children under five years old  in the Kenjeran sub district, Surabaya. This study was designed as a case control study using 12 cases and 12 controls as the samplers. This research was conducted in Kenjeran sub district  and took place from May to November 2017. Statistical test was using by chi square and multivariate logistic regression. The results of the study was that the cases of p neumonia in children under five years old were birth weight (p=0,01), nutritional status (p=0,01), sanitation house (p=0,03) and airborne bacterial number (p=0,01). Multivariate logistic regression test results showed that significant variables were nutritional status and airborne bacterial number. Nutritional status have the significance 0.04 (p <α) with OR=15,00. Airborne bacterial number  have the significance 0.04 (p <α) with OR=15,00. The conclusion of this study is nutritional status and airborne bacterial number  are associated with pneumonia under five years old. It is highly suggested to improve the quality of home health and child care.
Level of Airbone Toluene in Work Environment is Associated With Level of Urine Hippuric Acid in Printing Workers at Rungkut Surabaya
Authors: Irmasari Fardani
Published: January 2019

One of industrial hazards in printing can come from chemical elements. The chemicals that may be in the printing industry is toluene. Toluene used in 75% of printing work activity. The biggest toluen used as automatic cleaning. Other toluen used as a printing ink, solvent, varnish and glue. The purpose of this study was to analyze the relationship between airbone toluene levels with hippuric acid in workers Printing in Rungkut Surabaya. This research was an observational analytic, used cross sectional design. The sample of this study were 30 people, taken by random sampling. The results of pearson correlation test showed that there were a association between airbone toluene with hippuric acid in urine (p= 0.000; r=0.796) and results of pearson correlation test showed thatthere is no association between airbone toluene with eye irritation complaint (p=0.268). Its conclued that level of airbone toluene in work environment is associated with level of urine hippuric acid in printing workers at Rungkut Surabaya. Suggestions from this research is the company must conduct periodic monitoring in the airbone workplace of workers and to raise workers awareness of the importance of PPE.
B3 Waste Management and Health Workers Complaint In. Inka (Persero) Madiun City
Authors: Ichtiakhiri Tentrami Hayuning , Sudarmaji Sudarmaji
Published: January 2019

Abstract: Disposal  of industrial products containing chemical compounds especially harmful and toxic material negative impact  on the environment and human  health. PT. INKA (Persero)  is a company engaged in manufacturing and railway services generating B3 waste  from the production process.. B3 waste  is used oil/oil cooler  scars, B3 cans  (cans  of paint, thinner, drums), used batteries,  sand  ex. blasting,  dust ex. blasting,  plasma  crust, former rags, waste  fiber glass.  B3 waste containing various heavy  metals  such as Pb, Cu, Hg, and Fe. This can be avoided by doing  the B3 waste  management in industry.  The  purpose of this research is describing the  implementation of B3 waste  management and  perceived health  complaints of workers.  This research is a descriptive cross-sectional design. The sample of respondents was taken by total sampling with a sample size  of 10 workers  B3 waste management. The research variables  are B3 waste management (sorting, storage, collection, transportation, utilization, processing, stockpiling) and health complaints. The results  showed that PT. INKA (Persero)  has  not qualified  in terms  of B3 waste  management such as sorting  and storage. Health complaints are often perceived by employees is a headache and skin irritation. In this research required the  supervision of B3 waste  management in PT. INKA (Persero)  as well as increased awareness of workers  to wear protective equipment to manage waste.Keywords: B3 Waste Management, Health Complaints
Health Risk Characteristic Due to Air Pollution Exposure in Shoe Soles Workers (around Bubutan Road in Surabaya city)
Authors: Rahmadani Rahmadani , Tualeka Abdul Rohim
Published: January 2019

Abstract: Risk characterization is end of the risk assessment process. Toxin agent can enter the human body by inhalation process, skin (dermis) and digestion process. The objectives of this research is to determine risk characterization of exposure to air pollutans on the health of sole services worker. This study was an observational study with cross sectional approach. 25 people of this sampel study were the total population. Independent variabels were age, weight, lenght of work in this sector, lenght of exposure time, number of working days. Dependent variabels were the concentration of CO, SO2 and NO2. Data were analyzed descriptively and the result of the data would be narrated and shown on the frequency table. Result the exposure assessment of carbon monoxide parameter on sole services workers were gotten the highest intake value was 0.2028 mg/kg/day and the lowest value was 0.0085 mg/kg/day, sulfur dioxide parameter on sole services worker were gotten the highest intake value was 0.0004028 mg/kg/day and the lowest value was 0.0000169 mg/kg/day, nitrogen dioxide parameter on sole services worker were gotten the highest intake value was 0.01238 mg/kg/day and the lowest value was 0.00051 mg/kg/day. Based on the results of the research, it can be concluded that RQ < 1 showed that air quality is still safe. But, in fact is still founded the lamentation of the health disruption and the uncomfort air condition arround the survey area. Research of Refferences of Concentration (RfC) will be needed, especially for CO, SO2 and NO2 parameter fi t of the characteristic of Indonesian people and especially informal sector worker in Surabaya.Keywords: Risk Quotient, Exposure of CO, SO2 and NO2, Workers
The Physical and Chemical Air Quality, Worker’s Characteristics, and Respiratory Symptoms Among Printing Workers in Surabaya
Authors: Oktaviani Devi Anggar , Prasasti Corie Indria
Published: January 2019

Abstract: Printing industry is an industry which in its production process generate air pollutants such as Particulate Matter (PM). The exceeds limit of PM2,5 can cause respiratory symptoms, cardiovascular disease, and pulmonary function disorder. The objective of this study was to analyze physical and chemical air quality and respiratory symptoms among printing industry workers in Surabaya. It was observational study with cross sectional approach and analyzed descriptively. The physical and chemical air quality was measured by Thermohygrometer and Haz Dust EPAM 5000 at three different areas in production unit. Worker’s characteristics and respiratory symptoms were obtained from 20 respondent’s questionnaires. The highest concentration of PM2,5 level was at cutting room (area 1), which maximum concentration was 20.0 μg/m3 and the average was 6.1 μg/m3. The result showed that PM2,5 levels was below threshold limit value. It is suggested to printing industry to improve administrative control application by managing work period and useing mask, to clean ventilation, dust collector, or production facilities and to examine health status regularly to public health center for workers at printing industry.Keywords: physical and chemical air quality, printing industry, respiratory symptoms
Central Nervous System Complaint in Worker Exposed to Air Toluene in Car Painting Workshop in Surabaya
Authors: Agustina Ukik , Mukono Jojok
Published: January 2019

The existence of toluene in air work environment can affect in health worker, such as disruption of Central Nervous System (CNS), lung, kidney, eye, skin and complaint. Therefore, the aim of this research was to learn CNS complaint in workers in car painting workshop in Surabaya. The sample research was taken from total population that was appropriate with inclusion criteria. The sample total was 12 people. Air sampling was conducted by using NIOSH method number 1501 with pipe absorption material activated carbon (charcoal) that use Gas Chromatography (GC) technique. Hipurric acid was measure by NIOSH method number 8301. CNS complaint in workers was known by using Q18 questionnaire. It was standardized questionnaire to determine CNS complaint in people exposed to toluene. The result showed air toluene in painting room still in threshold level that was 18.5726 ppm. Urine hipurric acid level in painter worker showed still in threshold level with the highest urine hipurric acid in worker 0.32 g hippuric acid/g urine creatinine. It can be concluded that toluene level in air and urine hippuric acid were still in threshold level, painter workers showed a trend CNS complaint compired with administration workers. It is suggested to wear Personal Protective Equipment (PPE), such as mask for gas, gloves, glasses, special clothes and boots for working.
Air Formaldehyde Levels and Eye Irritation in Workers at Production Area of Wood Adhesive Factory in Surabaya
Authors: Raharyaningsih Mustika Ayu , Azizah R
Published: January 2019

Formaldehyde is a chemical substance that has volatile and short-term effect characteristics, which can cause eye irritation. Exposure to formaldehyde in low levels can cause irritation to human eyes. The purpose of this research was to study the production process, air formaldehyde levels and eye irritation at Wood Adhesive Factory workers in Surabaya. This study was an observational study with cross sectional design and analyzed descriptively. The variables studied were levels of formaldehyde in the air and eye irritation of workers. Results showed that the average levels of formaldehyde in three areas of production (formalin, liquid adhesive, and powder adhesive production) was 0.2102 ppm and 12.5% of respondents experiencing eye irritation had age between 26-35 years, working period less than 10 years, length of work 7 hours per day, not wearing personal protective equipment safety glasses (spectacles) and had a habit of smoking. The factory had provided personal protective equipment safety glasses (spectacles), but 37.5% of the respondents did not wear personal protective equipment when they were working. Hence strict supervision regarding the use of personal protective equipment is needed, especially safety glasses (spectacles) so that workers are more obedient in wearing personal protective equipment and eye irritation to workers can be avoided.
The Mudharabah Savings Demand among the Member of Islamic Financial Service Cooperatives in Bogor
Authors: Aisyah Muniaty , Umiyati U.
Published: January 2019

The Islamic Financial Service Cooperative or Baitul Maal wa Tamwil (BMT) is potential to become an effective economic driving forcefor micro and small businesses in Indonesia due to its ability to raise public funds. Nevertheless, BMT experiences many obstacles, one of which in marketing. It needs a better understanding of its member behavior that could predict the demand of its products and services. This research aimed to examine the members’ demand on Mudharabah savings of BMT in Bogor, by using the multiple linear regression analysis. The finding shows that the service quality does not influence the members’ decision to use Mudharabah savings because the services provided by BMT are below of members’ expectation, thus, they need to enhance their service quality. This research sheds the light on some strategies in order to improve service quality of BMT in Indonesia.
Food Safety Modernization Act Produce Safety Rule Compliance for United States Hard Cider Producers Using Ground-harvested Apples
Authors: Ewing Brianna L. , Rasco Barbara A.
Published: January 2019

Apples (Malus domestica) are considered covered, or “nonexcluded,” produce under the Food Safety Modernization Act Produce Safety Rule. The rule states that fruit that has unintentionally come in contact with the ground may not be used for human consumption unless there have been sufficient processing steps to reduce the risk of human pathogens in the final food product. Cider apples destined for hard cider production in many regions have traditionally been harvested at full ripeness when the fruit naturally drops or is easily shaken off the tree. This work reviews the status of cider apples under the Produce Safety Rule, presents the human pathogens of concern with usage of ground-harvested fruit, and describes recommendations, including processing steps, for cider apple growers and cider producers so they can ensure that their product is safe and that they are complying with the rule.
Ornamental Kale as a Cut Flower under High Tunnels in the Southeastern United States
Authors: O’Connell Suzanne
Published: January 2019

The potential to expand the production of ornamental kale (Brassica oleracea var. acephala) grown as a specialty cut flower in the southeastern United States appears promising, especially for the winter holidays. This 2-year replicated study investigated the effects of two fall plantings and three cultivars on ornamental kale yields grown under organic high tunnels. In addition to the production study, informal interviews of local florists were conducted. The earlier planting dates resulted in longer stem lengths (≥5 cm) and fewer days to harvest (≥5 days) across both seasons. Commercial stem length goals were not achieved (≥60 cm) but local florists did not appear to have the same standards (≥31 cm). The cultivars Crane Bicolor and Lucir White had longer stems and larger heads than Crane Red. Our high tunnel system provided favorable air temperatures for vegetative growth from late September through early November indicating an earlier planting date may be possible. Commonly accepted nighttime temperatures required to induce color changes occurred in early to mid-November during our study period.
Effect of Chilling and Photoperiod on Budbreak in Three Hybrid Grape Cultivars
Authors: Rezazadeh Amir , Stafne Eric T.
Published: January 2019

The present study assessed the effect of photoperiod on budbreak of cuttings of three interspecific hybrid grape (Vitis) cultivars that had received different chilling hours. Stem cuttings were collected at 100-hour intervals of chilling (200, 300, 400, 500, 600, 700, and 800 hours) from the vineyard and kept in three growth chambers with daylengths of 8, 16, and 24 hours. Another group of cuttings were maintained in a greenhouse with a natural daylength range of 10.5–13 hours [8 Dec. 2017 to 4 May 2018 (average = 12 hours)]. Chilling requirements, days to budbreak, and budbreak rate were determined after plants were exposed to different chilling hours and daylengths. Results of our study demonstrated that the chilling requirements of all three cultivars were adequately reached at 600 hours or more. Increasing chilling exposure from 600 to 800 hours shortened the time to budbreak in all cultivars. Overall, ‘MidSouth’ had an average budbreak rate of 90% when receiving at least 600 hours chilling. ‘Blanc du bois’ and ‘Lake Emerald’ had 62% and 65% average budbreak, respectively. Longer days (24 hours) reduced time to budbreak by 14, 6, and 8 days, respectively, in ‘Blanc du bois’, ‘Lake Emerald’, and ‘MidSouth’ at 600 hours chilling. A combination of 24-hour photoperiod and chilling of 600 hours resulted in a maximum budbreak rate of 70%, 70%, and 100% in ‘Blanc du bois’, ‘Lake Emerald’, and ‘MidSouth’, respectively. Our results indicate that breaking dormancy may be controlled by both temperature and photoperiod in these three cultivars.
Lung cancer morbidity and mortality
Authors: Merabishvili V. M. , Arseniev A. I. , Tarkov S. A. , Barchuk A. A. , Shcherbakov A. М. , Demin E. V. , Merabishvili E. N.
Published: January 2019

Background. According to a report by the International Agency for Research on Cancer (IARC), lung cancer (LC) is among the leading causes of morbidity and mortality worldwide, with an estimated incidence of 14.1                million new cases of the disease and 8.2 million cancer deaths in 2012. Lung cancer is the most common cancer worldwide, accounting for 13 % of all new cancer cases and 19.4 % of deaths.

The purpose of the study was to evaluate LC prevalence and to measure the quality of population-based cancer registries by the indices of the proportion of total incident cases.

Material and methods. The study material was given from the monograph «Cancer on Five Continents», which included data from the database of the Cancer Registry of PA. Herzen Moscow Research Oncology Institute (St. Petersburg), surveys of morbidity and mortality in the North-West Federal District, estimations of proportion of the true incidence that was registered in population-based registries.

Results. The analysis of lung cancer morbidity and mortality in Russia showed a significant improvement in analytical indices over the past 10 years, however, underestimation of primary cases, reduced the overall lung cancer incidence rate.

Conclusions. The dynamics of age-specific lung cancer incidence was shown. The loss of primary lung cancer cases was estimated to be 15-20 % annually.
Combined method for differential diagnosis of pancreatic cystic neoplasm
Authors: Koshel A. P. , Drozdov E. S. , Dibina T. N. , Klokov S. S. , Mironova E. B. , Rakina Yu. Yu.
Published: January 2019

Objective.The frequency of detection of cystic neoplasm of the pancreas (CNP) has recently increased. Some of these neoplasms are benign, while others are malignant. Differential diagnosis between benign and malignant CNP remains challenging.

Aim:to develop a combined method for differential diagnosis of CNP and to evaluate the role of the neutrophil to leukocyte ratio (NLR) as a diagnostic criterion of malignant CNP.

Material and Methods. A retrospective analysis of the treatment of 82 patients with CNP, who underwent surgery between 2008 and 2018, was carried out. Benign lesions were detected in 62 patients and malignant tumors were diagnosed in 20 patients. The NLR and the serum levels of CA 19-9 as well as the presence of intracystic lesions were assessed as predictors of malignant CNP.

Results. The presence of intracystic lesions detected by contrast-enhanced computed tomography and the elevated levels of serum CA 19-9 (>39 U/mL) and NLI (>1.876) were proven to be independent predictors of malignant CNP with statistical significance. The combination of all three criteria indicated malignant cystic neoplasm. The sensitivity, specificity and overall accuracy of the combined method were 71.4 %, 95.6 % and 86.5%, respectively.

Conclusions.The combined method for differential diagnosis of malignant CNP is easy to use and has high accuracy. There is a direct correlation between NLI and malignant CNP.
High density lipoproteins of blood plasma as a transport form of actinomycin D
Authors: Polyakov L. M. , Knyazev R. A. , Ryabchenko A. V. , Trifonova N. V. , Kotova M. V.
Published: January 2019

Introduction.The development of new and highly effective antitumor therapy is one of the priorities of pharmacology. The paper presents one of the solutions to the problem related to the development of transport forms of antitumor drugs.

The aimof the study was to study the ability of various fractions of plasma lipoproteins (VLDLP, LDL, HDL) to interact with actinomycin D and show the role of HDL as a transport form of actinomycin D in the body cells.

Material and methods. The studies were conducted using unlabeled and tritium-labeled actinomycin D, preparative ultracentrifugation of the rat plasma lipoprotein fractions, chromatography, and in vivo experiments with intravenous administration of HDL complexes with labeled actinomycin D.

Results.The important role of HDL in the formation of complexes with actinomycin D in comparison with LDL and LPA was shown. The basic physicochemical characteristics of the interaction of HDL and apolipoprotein A-I with actinomycin were obtained. The constants of the association were of the order of 105 M-1, and the number of binding sites for the drug was 26 for HDL and 12 for apolipoprotein A-I. In vivo studies on rats, the highest radioactivity after intravenous injection of HDL complexes with tritium-labelled actinomycin D was observed in the adrenal glands, then in the liver and kidneys. The uptake of tritium-labelled actinomycin D was twice lower in the lungs, adipose tissue, thymus and spleen. The low uptake of the label was observed in the myocardial tissue.

Conclusion.The results obtained demonstrate the feasibility of using HDL as a transport form of actinomycin D in body cells.
THE STUDY OF ODOR PROFILE AND COLOR CHARACTERISTICS IN BEEF DURING HEAT TREATMENT
Authors: Lovkis Zenon V. , Pochitskaya Irina M. , Komarova Natallia V.
Published: January 2019

The article presents the study results of changes in the odor profile and color characteristics in beef under various heat treatment conditions. More than 120 volatile substances are identified. In samples subjected to short-term and minor heat treatment, 2-methyl-butene and ethyl hexanoate were found in significant amounts. In samples subjected to prolonged roasting at low temperature, as well as in samples subjected to processing at higher temperature for less time period, was found 3,5-dimethyl–4-octanone. Analysis of changes in color characteristics showed that increase in heating temperature results in significant darkening of the samples. The maximum heating temperature of 210 °C had the most significant effect on the color change. After heating for more than 30 minutes, carbonization of the samples occurred. The results indicate that controlling the temperature and duration of heat treatment helps to obtain the finished product of desired color.
Proper nutrition at early age as the key to future health
Authors: Panasenko L. M. , Kartseva T. V. , Nefedova Zh. V. , Zadorina-Khutornaya E. V. , Khokhlova E. V.
Published: January 2019

Each period of childhood is characterized by its own peculiarities of growth and development, the degree of morphological and functional maturity of individual organs and systems, the specifics of physiological and metabolic processes. Rational feeding and nutrition play a significant role in a child’s health. The authors presented modern approaches to the complementary food for children, its timing, taking into account the child’s readiness to receive new food, the composition of the dish, feeding technique, the formation of proper eating habits and behavior. The literature actively discusses the problem of the formation of taste preferences at early age; thisisthe period for the first acquaintance with varioustastes. The article demonstratesthe advantages of using products of industrial production. It is particularly important to overcome the negative attitude to new products – it determinesthe attention of the specialists to the problem of the introduction of complementary foods.

Conflict of interest: The authors of this article confirmed the lack of conflict of interest and financial support, which should be reported.
Analysis of statistical indicators of congenital anomalies as causes of early neonatal death in the Russian Federation
Authors: Tumanova U. N. , Shuvalova M. P. , Schegolev A. I.
Published: January 2019

The article contains the analysis of Rosstat data for 2012–2016 on early neonatal death due to congenital developmental anomalies. From 2012 to 2016 there was an annual progressive decrease in the number of early neonatal deaths (from 6969 to 4113) in the Russian Federation. The total number of newborns died in the first 168 hours of life due congenital anomalies decreased from 1126 (2012) to 759 (2016), while the values of early neonatal mortality decreased from 366.4 to 217.8. However, the proportion of such infants increased from 16.2% (2012) to 18.5% (2016) from the total number of deaths in the early neonatal period. The type of defects and the frequency of their registration as the initial cause of early neonatal death differ in the federal districts of the Russian Federation and there are certain gender differences.

Conflict of interest: The authors of this article confirmed the lack of conflict of interest and financial support, which should be reported.
FUZÛLÎ’NİN ŞİİR ESTETİĞİNDE GÜZELLİĞİN PROTOTİPLERİ
Authors: BOZKURT Kenan
Published: January 2019

Fuzûlî’nin estetiğinde güzelliğin ne olduğu hususu, doğrudan ele alınıp işlenmediği gibi güzelliğin bizzat kendisi anlatılmaz. Şâir, güzelliği en yetkin örnekleri üzerinden hareketle anlatma yoluna gider ki bunlar, genelde güzelliği kâmil bir şekilde ortaya koyacak görsel varlıklar, güzelliğiyle dillere destan olmuş şahıslar, soyut ya da sanatsal yönü olan varlıklardır. Güzelliği karşılamak için şâirin kullandığı prototipler, insan zihninde anlamlanan, farklı obje ve olguların değişebilen ortak özelliklerini yansıtan temsil objesine dönüşür. Böylece güzelliği temsil eden prototip, zihin ve dil arasındaki ilişkinin en önemli unsuru olur. Hatta prototip, güzelliğin yerini alacak bir temsiliyet kazanır. Fuzûlî’nin güzellik için kullandığı benzetilen unsur ile güzellik arasında kurduğu özdeşlik, parçanın bütüne ait tüm anlamsal içerimleri kapsadığından güzelliğin kemâlini anlatacak sıfatlara gerek duyulmaksızın prototip üzerinden güzellik, kâmil bir şekilde anlatılmış olur. Şâirin başvurduğu bu anlatım yolu, prototipler üzerinden hareketle güzelliği anlatmaktır.Bu çalışmamızda Fuzûlî’nin şiir estetiğinde güzelliğin ifade aracı olan prototipleri ve bu prototiplerin işlevi, türleri ve nasıl oluşturulduğu üzerinde duracağız.
Promising areas of zeolite application in milk purification from toxic elements
Authors: Какимов Айтбек , Kakimov Aitbek , Какимова Жайнагуль , Kakimova Zhaynagul , Смирнова Ирина , Smirnova Irina , Жарыкбасов Ерлан , Zharykbasov Erlan
Published: January 2019

The article reveals the data on lead and cadmium content in raw milk samples taken in seven areas located in two districts of Semey Territory of East Kazakhstan Region (Abay and Ayagoz Districts). The authors determined high content of lead (from 0.11 to 0.15 mg/l) in milk samples taken in the populated areas which are located closer to the territory of the former Semipalatinsk Nuclear Test Site. To reduce the content of toxic elements in raw milk the authors developed an experimental filtration unit using natural zeolite brought from Tarbagataysky deposit (East Kazakhstan Region) as sorption-filtering material. Natural zeolite module SiO2/Al2O3 consists of 6.3 units which characterizes it as a high-purity clinoptilolite, highly efficient sorption ion-exchange material. As a result of the experiments the authors determined that natural zeolite taken from Tarbagataysky deposit of East Kazakhstan Region shows sorption properties in relation to lead and cadmium ions. Zeolite application as a sorption-filtering material helps reduce cadmium and lead ion content in milk during filtration. The most suitable processing parameters of milk filtration which help change the content of the considered elements significantly are the following: filtration temperature should be 18–20°C, pump rotation frequency – 300 rpm with filter of the experimental unit which consists of 200 g of natural zeolite. Besides, the authors studied the changes in organoleptic, physical and chemical properties of milk during filtration. The authors determined that organoleptic, physical and chemical properties during milk filtration using natural zeolite as a sorption-filtering material do not change and comply with the regulatory requirements which specify fresh milk quality parameters. Titratable acidity of milk reduces insufficiently.
Water treatment in food industry
Authors: Краснова Тамара , Krasnova Tamara
Published: January 2019

The author considered the contemporary state of the issue of water treatment in food and beverages production. The article presents regulated water quality parameters for drinking and bottled water, for dairy industry, beer and soft drinks production, as well as for production of vodka, vodka for export, and baby food. The article shows that water from central utility and drinking water supply needs additional treatment to produce food and beverages. It should be cleaned from hardness salts, iron, manganese, mineral salts, organic compounds and microbial contamination. Besides, many companies use groundwater sources (from wells). That makes water treatment procedure even more complicated. The author considered such treatment methods as ion exchange, magnetic water treatment, catalyzed oxidation, deferrization using sorption-filtering materials from mineral raw materials, aeration, reverse osmosis, electrodialysis, activated carbon adsorption. The author shows the treatment mechanisms, their advantages and disadvantages. The article indicates which materials and equipment can be used to apply these methods in water treatment practice. It describes new techniques for effective water treatment such as radiolysis, cavitation and advanced oxidation treatment techniques. It gives flow diagram of bottled water production depending on its origin and content of impurities which is used by the companies working in Gelendzhiksky district, Lipetsk and Kemerovo. The author analyzed the contemporary state of the issue of water treatment in food and beverages production companies based on the available information and assessed the technical level of water treatment systems. The article reveals that only companies which produce alcoholic drinks such as vodka, liquors, and beer use a number of water treatment procedures which meet modern requirements. In general, food production companies face water treatment issue. Labor intensive, expensive and non-environmentally friendly water treatment methods are used everywhere. But they do not always guarantee required water quality. For that reason water treatment schemes in food industry should be revised. The author gives recommendations to replace traditional technologies with modern ones.
Using food wraps based on gelatin to preserve food quality
Authors: Сергазиева Ольга , Sergazieva Olga , Долганова Наталья , Dolganova Natalya
Published: January 2019

The research in the given sphere is essential because it is concerned with the development of ecologically clean natural edible food wraps production technology using fish industry waste products. The article presents the results of the studies devoted to the consideration of properties and possibilities of using edible food wraps based on ichthyo-gelatin to preserve quality of different food products. To produce edible food wrap the author used gelatin obtained from the waste products (fish scale) of fish-processing industry (ichthyo-gelatin). The wrap was produced based on ichthyo-gelatin with concentration from 5 to 15% and plasticizer (glycerol with concentration from 2 to 20%). All obtained wraps were subject to quality control considering organoleptic (flavor, color, look) and physicochemical properties (pH, moisture content, dissolution rate, film thickness, breaking stress at stretching, water vapor permeability). The obtained results showed that it is possible to use food wraps based on ichthyo-gelatin in public catering. Changes in plasticizer proportion made it possible to produce two types of film: the first one was thicker (2% of plasticizer) having low stretching ability it can further be used in production of bags for products storage and freezing; the second type of the film (5% of plasticizer) can be used to produce colorful films with prints which can be applied for protective and decorative wrapping of confectionery products. To use the developed films as a protective wrapping for cold dishes (such as salads and various cold cuts), to protect banquet dishes against drying and thick film formation it is necessary to pay especial attention to water vapor permeability of the film its dependence on the proportion of plasticizer and thickness. Variability of this parameter can extend the application sphere of the developed edible film.
THE CONCEPT OF PROFESSIONAL AND STATUS SELF-REALIZATION
Authors: Ушаков Дмитрий , Ushakov Dmitri
Published: January 2019

The article reveals the essence, characteristics, content, and connection of the concepts of "self-realization", "self-actualization" and “professional and status self-realization of personality”. The author provides a comparative analysis of the scientific works by domestic and foreign scientists studying the problem of self-realization and justifies his own understanding of view on the matter. The article determines the specifics of the interdisciplinary interpretation of the concept of "status of professional self-realization of personality" in sociology.