bluuebunny/crossref_metadata_2025 huggingface dataset:
Trimethylamine. Documentation of proposed values of occupational exposure limits (OELs)
Authors: Jankowska Agnieszka , Czerczak Sławomir
Published: December 2018

Trimethylamine (TMA) is a gas at ambient temperature, which has a pungent, fishy odour. It is commercially available as a compressed gas, 40% aqueous solution or a 33 % solution in ethanol. It is used in organic synthesis, especially of choline salts, as a warning agent for natural gas and flotation agents, in the production of cationic starches, quaternary ammonium compounds, intense sweeteners and strongly basic anion exchange resins. Moreover, it is used in the production of disinfectants and insect attractants. TMA is irritating to the human respiratory tract, skin and eyes. The threshold of irritation was reported to be 1481 mg/m3 (median) after a single dose. No effects were observed in workers exposed to 0.24-19.5 mg/m³, most measurements being below 12.1 mg/m3. A LOAEC of 48 mg/m³ was established for human based on eyes, nose and throat irritation.
Animal data with repeated inhalation exposure over 2 weeks revealed a LOAEC of 183.75 mg/m³ based on respiratory irritation in a rat study.
Embryotoxic effects were observed in mice (NOAEL of 150 mg/kg bw/day).
The Scientific Committee for Occupational Exposure Limits to Chemical Agents (SCOEL) has established OEL of 4.9 mg/m³ and STEL of 12.5 mg/m³.
A MAC value has been derived using the RD50 value (147.62 mg/m3 for TMA) and multiplying it by a factor of 0.03. The Expert Group for Chemicals Agents has proposed to reduce the current MAC value from 12 mg/m³ to 4.9 mg/m³ and the current STEL value from 24 mg/m³ to 12.5 mg/m³, which is also in accordance with the values recommended by SCOEL. It has been proposed to remain the “I” (irritant) labelling of TMA. No bases for a BEI value have been found.
DEVELOPMENT OF THE METHOD OF INDIRECT STEGANOGRAPHIC DATA HIDING IN THE CONTAINER IMAGE CONTOUR
Authors: Barannik Volodymyr , Shatun Oleg , Barannik Dmitriy , Kobtseva Veronika
Published: December 2018

The article discusses issues related to the use of methods of digital steganography for information security in systems of critical appointment. The advantages of using data embedding in an image container are shown. The main disadvantages of the existing methods of embedding in the image container are given. The issues of JPEG image compression for digital steganography are described. The allocation of stable regions in the attacking effects on the basis of the moving mask is proposed. The mathematical apparatus for masking images by the Sobel method is shown. The indirect steganography method of hiding data in blocks which contain information about the circuit is developed.
STEGANOGRAPHY METHODS USED IN ATTACKS ON INFORMATION AND COMMUNICATION SYSTEMS
Authors: Romanova Anna , Toliupa Sergiy
Published: December 2018

An analysis of steganography methods that are can be potentially used as instruments in attacks on information and communication systems is presented. The possible solutions to ensure resilience to such attacks are presented.
METHOD OF SAFE LANDING THE EMERGENCY QUADROCOPTER
Authors: Blagitko Bohdan , Mochulsky Yuriy
Published: December 2018

By means of mathematical modelling, the main features of emergency landing of quadrocopter are determined. The results of simulate landings of the quadrocopter in cases of failure of one of four pairs of electric motor screw are given. The methods of safe landing of an unmanned quadrocopter in case of failure of one of four pairs of motor-screw are proposed. The basis of the proposed methods is to use a parachuting effect. Parachuting achieved by forced off the power of the motor, which is located at the opposite end of the same yoke as faulty motor. As a result, the vertical speed of the quadrocopter at the time of landing significantly decreases in comparison with the speed of free fall.
IMPROVEMENT OF METHODS OF MOTION COMPENSATION OF DYNAMIC OBJECTS MOVING IN VIDEO STREAM OF THE VIDEOCONFERENCING SYSTEM
Authors: Barannik Volodymyr , Dvorsky Mykola , Barannik Valeriy , Himenko Viktoria , Sorokun Anton
Published: December 2018

Videoconferencing gives us the opportunity to work and communicate in real time, as well as to use collective applications, interactive information exchange. Videoconferencing systems are one of the basic components of the organization of manegment, ensuring, the timeliness and necessary quality management of the implementation of objective control over the solution of the tasks. The quality of the image and the time of transmission of video information is unsatisfactory for the quality control of the troops. Considered ways to increase the efficiency of management and operational activities, due to methods of compensation of motion, using technology to reduce the volume of video data for quality improvement.
INFLUENCE OF MOBILE ROBOT CONTROL ALGORITHMS ON THE PROCESS OF AVOIDING OBSTACLES
Authors: Wójcicki Piotr , Powroźnik Paweł , Żyła Kamil , Grzegórski Stanisław
Published: December 2018

This article presents algorithms for controlling a mobile robot. An algorithms are based on artificial neural network and fuzzy logic. Distance was measured with the use of ultrasonic sensor. The equipment applied as well as signal processing algorithms were characterized. Tests were carried out on a mobile wheeled robot. The analysis of the influence of algorithm while avoiding obstacles was made.
Analytical Method for Lactoferrin in Milk-Based Infant Formulas by Signature Peptide Quantification with Ultra-High Performance LC-Tandem Mass Spectrometry
Authors: Ellingson David J , Shippar Jeffrey J , Vennard Thomas R , Moloney Cian , O’Connor Deborah , O’Regan Jonathan , McMahon Adrienne , Affolter Michael
Published: December 2018

Background: There is a need for a standardized method for quantification of lactoferrin in infant formulas, and manufacturers have started fortifying lactoferrin to mimic the higher levels found in human milk. A variety of current methods exist, but specificity and accuracy are challenging with the infant formula matrix. The use of signature peptides and MS is becoming more prevalent in the realm of analytical chemistry for quantification of proteins. Objective: The objective of this work was to develop and validate a method through a single-laboratory validation for quantification of lactoferrin in milk-based infant formula and begin to lay the foundation for a standardized method. Methods: The method presented uses signature peptides to quantify lactoferrin in milk-based infant formulas by ultra-high performance LC-tandem mass spectrometry (MS/MS). These peptides are produced through tryptic digestion, and fragments produced from these peptides through MS/MS allow the specific quantification using correlating isotopically labeled peptides. Results: The validation parameters were all met with precision RSDr ranging from 2.1 to 7.1 and intermediate RSDR ranging from 7.0 to 10.4 across different fortified milk-based infant formulas. Accuracy with certified reference material resulted in mean recoveries of 91.7–96.4%. Conclusions: The results from this study demonstrate the method is fit for purpose to support manufacturing specifications and nutritional labeling requirements.
Repeatability and Methodical Actions in Uncertain Situations
Authors: Funk Michael ,   Philosophy Documentation Center
Published: December 2018

In this paper Ludwig Wittgenstein is interpreted as a philosopher of language and technology. Due to current developments, a special focus is on lifeworld practice and technoscientific research. In particular, image-interpretation is used as a concrete methodical example. Whereas in most science- or technology-related Wittgenstein interpretations the focus is on the Tractatus, the Investigations or On Certainty, in this paper the primary source is his very late triune fragment Bemerkungen über die Farben (“Remarks about the Colours”). It is argued that Wittgenstein’s approach can supplement Don Ihde’s concept of material hermeneutics, and that Wittgenstein’s constructivist and pragmatist claims relate to current authors in the philosophy of technology like Peter Janich, Carl Mitcham or Jürgen Mittelstraß. Ludwig Wittgenstein enables a philosophical approach of transcendental grammars, techno-linguistic forms of life and technoscientific language games. In detail, several methodological aspects regarding relations between language and technology are summarized. Here concretely repeatability and methodical actions play major roles in uncertain situations of language and technology practice. It is shown that Wittgenstein is still underestimated in the philosophy of technology—although his thoughtful conceptualizations of language, social practice and technology bear important methodical insights for current technosciences like synthetic biology, robotics and many others.
Two new species of Yaginumaella (Araneae, Salticidae) from Wuling Mountain, China
Authors: Li Dan , Wang Cheng , Irfan Muhammad , Peng Xian-Jin
Published: December 2018

The present paper deals with two new species, Yaginumaella pulchella sp. nov. and Yaginumaella hubeiensis sp. nov. Distributional data, as well as illustrations of body and copulatory organs, are provided. Descriptions of their morphology are given. The differences between the new species and their related taxa are discussed.
Memoria subalternoak Mikel Peruarenaren nobelagintzan
Authors: Sarasola Santamaria Beñat
Published: December 2018

Artikulu honek Mikel Peruarenaren nobelagintza aztertzen du memoria ikasketen ikuspegitik. Zehazki, memoria subalternoak fikzioaren bidez berreskuratzeko Peruarenak egiten dituen ahaleginak aletzen dira. Hala, alde batetik, euskal memoria hegemonikotik aparte dauden bi pasarte historiko gogorarazten dituzte Ez obeditu inori eta Su zelaiak nobelek; hurrenez huren, Kubako Independentzia Gerra eta Lehen Mundu Gerra. Bietan ere memoria eta identitate subalternoekiko jaidura eta sentsibilitatea sumatzen da. Bestetik, nobelotan, memoria lantzeko ohikoak diren hainbat elementu narratibo aurkitzen ahal dira, zeinak ezinbestekoak diren memoria subalternoen soslaia osatzeko.This article analyses Mikel Peruarena’s novels under memory studies perspective. More precisely, it researches the way Peruarena revives subaltern memories through his fiction. Thus, on one hand, the novels Ez obeditu inori and Su Zelaiak restore two historical chapters that have been forgotten within Basque hegemonic memory; respectively, Cuban War of Independence and First World War. In both cases, it can be seen a sensibility towards subaltern memories and identities. On the other hand, in these novels appear several narrative elements that are common in memory literature, and they are key to complete the subaltern memory character of them.
Pequeña semblanza de Guillermo Díaz-Plaja
Authors: Abad Nebot Francisco
Published: December 2018

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Nota previa
Authors: Ysern Josep
Published: December 2018

Nota previa a "Actividad del Máster"
Revisiting the Base-Ten Block Challenge
Authors: Chaput Cathy M. , Smith Beth
Published: December 2018

Introducing a problem to children is always exciting when your goal is to challenge them in more than one way. The Base-Ten Block Challenge, published in TCM's January/February 2018 issue, has two layers to the activity. Conceptually, it has the challenge of using familiar materials more flexibly. In addition, this problem incorporates the strategy of Complex Instruction (CI), which aims to make group participation more equitable for all members through using random grouping and tasks with multiple entry points as well as ensuring that all students are accountable for understanding (Featherstone et al. 2011). A grade 2 class in Guelph, Ontario, Canada, took on this challenge, facilitated by a program coordinator in collaboration with their classroom teacher, Mrs. Beth Smith.
“Sliding” into an Equitable Lesson
Authors: Buchheister Kelley , Jackson Christa , Taylor Cynthia
Published: December 2018

A kindergarten teacher uses Gutièrrez's Four Dimensions of Equity to design and facilitate geometry instruction.
Measuring Penny
Authors: Lee Mi Yeon , Francis Dionne Cross
Published: December 2018

Activities generated from a children's book can support youngsters in developing conceptions of measurement.
GEOMETRICAL AND ELECTRONIC STRUCTURE OF PROPYL-, TETRAMETHYL-, DIMETHYLETHYL- AND BUTYLADAMANTANES AND THEIR THERMODYNAMIC CHARACTERISTIC ACCORDING TO DFT
Authors: Saginayev Amanzhan T. , Bagrii Evgenii I.
Published: December 2018

Propyladamantanes were synthesized by alkylation of adamantane with isopropyl alcohol in the temperature range from 5 to 40 °C in the presence of 96% sulfuric acid. Tetramethyl- and dimethylethyladamantanes were synthesized by isomerization of perhydroanthracene in the presence of aluminium oxide catalyst on the setup of the flow type. Isomers of butyladamantanes were obtained by the reaction of alkylation of the adamantane with isooctane. For each molecule, the optimization of the geometric parameters of atoms was carried out using analytical calculation methods. By calculating the frequencies of normal vibrations using the second derivatives, it was confirmed that the stationary points determined by optimizing the geometry correspond to the minima of the potential energy surface. The structure of 1-n-propyladamantane (I), 1-isopropyl-adamantane (II), 2-n-propyladamantane (III), 1,2-di-n-propyladamantane (IV), 1,3-dimethyl-5-ethyladamantane (V), 1,3,5,6-tetramethyladamantane (VI), 1,3,5,7-tetramethyladamantane (VII), perhydroanthracene (VIII), 1-n-butyladamantane (IX), 1-isobutyladamantane (X), 1-sec-butyladamantane (XI) has been studied using the DFT method with the Becke–Lee–Yang–Parr hybrid energy functional of electron density with the 6-31G* basis set. The geometric and electronic characteristics of the compounds and their total energy, normal vibration frequencies have been calculated. It has been shown that the calculated Gibbs free energies of formation for the perhydroanthracene isomerization products are in qualitative agreement with the experimental product composition of the isomerate and alkylation of adamantane with isopropyl alcohol are in qualitative agreement with the experimental composition of the products. A good agreement of calculated and experimental data on the composition of equilibrium mixtures was obtained. The theoretical geometry of the synthesized alkyladamantanes with Td symmetry very well agrees with the results of electron diffraction. Closest to the results obtained experimentally, the geometry was predicted by B3LYP, in which the lengths of C-C and C-H bonds are close to 1.544 and 1,100Ả, respectively, and the C-Csec-C and C-Cter-C angles are 109°. The results of the calculation using the B3LYP method are in good agreement with the experimental data. There is no definite relationship between the size of the molecules and the convergence of the calculated and experimental data. A practically important conclusion arising from the results of this and previous studies is that the use of the calculation method leads to “chemically accurate” data.
SYNTHESIS AND STRUCTURE OF POTASSIUM TETRAETHYLAMMONIUM HEXATHIOCYANATOPLATINATE(IV)
Authors: Sharutin Vladimir V. , Sharutina Olga K. , Tkacheva Alena R.
Published: December 2018

Potassium tetraethylammonium hexathiocyanatoplatinate(IV) (Et4N)(K)[Pt(SCN)6] (I) was synthesized by the reaction of potassium hexathiocyanatoplatinate(IV) with tetraethylammonium chloride in acetonitrile aqueous solution. Slow evaporation of the solvent led to the formation of large red-brown crystals. The product structure was determined by XRDA. The X-ray diffraction pattern of crystal I was carried out on a Bruker D8 QUEST diffractometer (MoKα radiation, λ = 0.71073 Å, graphite monochromator). [С14H20N7KPtS6, M = 712.92, Crystal system monoclinic, space group C 2/c, a = 10.432(8), b = 14.767(13), c = 16.300(13) Å, V = 2510(4) Å3, Z = 4, µ = 6.272 mm-1, F(000) = 1384, crystal size 0.86×0.66×0.50 mm]. The tetrahedral configuration of the tetraethylammonium cation is slightly distorted (CNC angles are 105.5(5)º-111.8(4)º, bond lengths N-С are 1.503(5)-1.519(5) Å). Platinum ions in anions have octahedral coordination (trans-angles SPtS are 180º, cis-angles SPtS are (88.47(4)º-91.53(4)º). The bond lengths Pt-S are equal to 2.373 (2)-2.37(2) Å. Potassium cations are coordinated by six nitrogen atoms of thiocyanate groups (distances N K (2.828(4)-2.896 (4) Å). Trans-angles NKN (128.44 (15)º-146.9 (2)º) are far from ideal values for the octahedron. Bridged thiocyanate ligands are bonded cations of the platinum and potassium. Ambidentate thiocyanate ligands are simultaneously coordinated to the K+ cation by nitrogen atoms. By means of the bridged thiocyanate ligands a three-dimensional coordination polymer is formed. The resulting structure is a three-dimensional grid, in the cells of which the cations of tetraethylammonium (Et4N)+ are located.
Digital literacy - a qualitative systematic review
Authors: Tamborg Andreas Lindenskov , Dreyøe Jonas Meldgaard , Fougt Simon Skov
Published: December 2018

Based on searches in Academic Search Premier, ERIC, SCOPUS and ORIA the paper reviews a total of 55 papers, this paper presents a review of how digital literacy is defined, interpreted and used in the research literature in the context of primary/elementary education. The paper identifies that digital literacy both are interpreted as the skills, knowledge and reflective practical abilities needed to be digitally literate, and as an emergent empirical phenomenon that needs to studied exploratively. Further, we identify that digital literacy is studied within various theoretical perspectives which imply many different interpretations of how it should be studied and that studies often lack a definition of what is meant by digital literacy. Conclusively, it is argued that there are important potentials in maintaining the broadness of how digital literacy can be defined, used and interpreted, but what rigorous explanations of how it is used in the given study is required for the broadness of the concept to be an asset.
Metodelygten - Når standardiseret ledelsesinformation forandrer socialarbejderens handle- og refleksionsrum
Authors: Christensen Michael , Madsen Martin Alexander
Published: December 2018

Artiklen fokuserer på, hvordan et stramt forvaltningsmæssigt fokus på standardiserede data og løsninger kan producere en række blinde pletter og uhensigtsmæssige praksisser i det sociale arbejde. Hvis metoderne implementeres for rigidt som en del af en forvaltningsmæssig styringsog handlingsramme risikerer socialarbejderne at blive fremmedgjorte og miste kontrol over eget arbejde.
De l’éducation inclusive à une communauté éducative pour tous
Authors: Chatenoud Céline , Ramel Serge , Trépanier Nathalie S. , Gombert Anne , Paré Mélanie
Published: December 2018

Si les écrits scientifiques actuels et de nombreuses orientations politiques internationales invitent les milieux scolaires à mettre oeuvre le projet de l’école inclusive, l’accès à l’éducation dans l’école de leur communauté est loin d’être un droit acquis pour tous les enfants. Ce numéro spécial propose une réflexion portant sur les enjeux majeurs d’une communauté éducative inclusive. Les articles mettent en exergue la responsabilité dans la mise en oeuvre de cette communauté non seulement du personnel scolaire, mais également de façon plus large de tous les acteurs qui ont à coeur d’abattre les barrières conduisant à l’exclusion. Dans un premier temps, cet éditorial pose les bases conceptuelles tant du côté des pratiques pédagogiques que de la formation. Dans un second temps, il met en contexte les articles publiés dans ce numéro thématique qui alimentent une réflexion amorcée lors d’un colloque du Réseau de recherche en éducation et en formation (REF) en 2015. L’ensemble vise à explorer la nature des savoirs transmis et véhiculés au sein de la communauté éducative inclusive que ce soit au sein, comme en dehors de l’école.
Os desafios da evangelização com as novas tecnologias digitais
Authors: Habowski Adilson Cristiano , Conte Elaine
Published: December 2018

O presente ensaio analisa a possível relação entre a evangelização cristã e as tecnologias digitais, identificando as (in)viabilidades de uma propagação e vivência da fé por meio das tecnologias no cenário social, político e religioso que se descortina no século XXI. É um estudo imprescindível para a Igreja, bem como para as reflexões teológicas, visto que estamos numa sociedade entrelaçada por influências globais e interconexões com o outro, o diferente, a constante inovação, a rápida interação e as diversas manifestações discursivas depositadas no ciberespaço. Concluímos que existe uma determinada banalização das coisas sagradas e das mensagens de fé associadas ao religioso no ciberespaço. O cuidado reside para que essa nova forma de evangelização não sofra deturpações da postura reflexiva perante a vida, à construção da própria identidade (suscetível à necessidade de velocidade desorientadora) imposta pelo ritmo contemporâneo da indústria cultural.
Tradições, transições e transformações: missão além de ad gentes
Authors: Andrade Joachim
Published: December 2018

A Missio Dei — tradicionalmente entendida como o sair amoroso de Deus para além de Si, rumo à Criação — representa a origem de toda missão, em movimento de saída de uma cultura para a outra, de um lugar para o outro. Esta saída em missão inspira-se, pois, no próprio Deus Uno e Trino, que Se comunica na pessoa de Jesus, sua Palavra enviada, donde nasce posteriormente a missão da Igreja. Ao longo da história, este envio foi compreendido pela Igreja como uma tradição a ser preservada e aplicada na ação missionária. Conforme a época, região e cultura essa tradição sofreu modificações, possibilitando as transições necessárias para readequar o propósito da missão, especialmente “ad gentes”. Sucedem-se os períodos apostólico, monástico, mendicante, dos Descobrimentos e Modernidade. Após o Concílio do Vaticano II, a missão passou por novas mudanças, com valorização do diálogo inter-religiosos e intercultural: passou-se da missão “ad gentes” para a missão “inter gentes”, com novos rumos e interlocutores.
Espiritualidade missionária
Authors: Balsan Luiz
Published: December 2018

Este artigo apresenta uma reflexão sobre os elementos fundamentais da espiritualidade missionária numa perspectiva cristã. Não raro percebe-se na ação pastoral e às vezes até mesmo na reflexão teológica uma compreensão redutiva da espiritualidade entendida apenas como vida interior. Nesse caso, espiritualidade se refere à oração, silêncio e introspecção. Seu sentido, porém, é muito mais amplo! Espiritualidade é vida no Espírito; é a totalidade da vida enquanto animada pela presença e pela ação do Espírito. A partir dessa compreensão, o artigo busca apresentar os elementos essenciais da espiritualidade missionária.
A unidade na martyria: a dimensão testemunhal do empenho ecumênico nos discursos do papa Francisco
Authors: Colet Raquel De Fátima , Andrade Rodrigo De
Published: December 2018

Entre as opções e os gestos significativos do papa Francisco está a busca fraterna pelo diálogo e cooperação entre as diversas confissões cristãs, expressão da cultura do encontro que tem marcado seu pontificado. A aproximação das lideranças das igrejas e das comunidades de fé, seja por atos oficiais ou por circunstâncias diversas que oportunizam essa relação, explicita a convicção eclesial da importância e urgência do empenho ecumênico. Partindo dessa premissa, este artigo visa identificar e apresentar nos discursos de Francisco os elementos que fundamentam a busca pela unidade cristã, tendo como chave hermenêutica a dimensão testemunhal - martyria, expressa, sobretudo, a partir de três vias: o caminho espiritual; o compromisso com a paz, a justiça e a integridade da criação; e a solidariedade ativa e profética para com os pobres. Esse itinerário permite perceber os apelos e horizontes para a práxis das igrejas em vista de um testemunho comum e genuíno da fé cristã.
O diálogo no Concílio Vaticano II
Authors: Passos João Décio
Published: December 2018

O presente trabalho trata da temática do diálogo como uma das palavras-chave do Concílio Vaticano II. O processo conciliar adotou, por força do confronto das diferenças, por persuasão da palavra e por audição da alteridade, o caminho do diálogo, de modo a romper com o método clássico, visível nos demais concílios, por meio do qual a verdade era reafirmada de modo autoritativo, exclusivista e restritivo. A própria intencionalidade do concílio, desde a convocação da parte do papa João XXIII, focada sempre no aggiornamento, até a aprovação dos documentos finais, adota o diálogo como caminho sempre mais consciente, na medida em que a Igreja ali presente dá a si mesma o desafio de discernir e acolher o mundo moderno. E, numa circularidade virtuosa, com essa postura revê a si mesma nos termos de sua definição e missão. O diálogo, como principio e caminho de construção do Vaticano II, constitui o legado maior do grande sínodo ecumênico no que se refere à práxis da Igreja no mundo e a sua própria autocompreensão como corpo feito de diversidade e unidade e povo de Deus em marcha na história na direção do Reino de Deus.
Coalizão Inter-Fé em Saúde e Espiritualidade: uma experiência de diálogo inter-religioso
Authors: Saad Marcelo , Peres Mário , Bizon José , Disk Lia , Fontão Paulo Celso Nogueira
Published: December 2018

O objeto do artigo é compartilhar a experiência de formação e trabalho do grupo do Coalizão Inter-Fé em Saúde e Espiritualidade, que desde 2015 vem construindo um ambiente de diálogo ecumênico e inter-religioso com a meta de estabelecer um modelo de apoio espiritual, nos moldes da capelania hospitalar praticada em vários países como o Estados Unidos, que traz obviamente a competência cultural e religiosa de cada um e amplia no sentido de acolher todas as pessoas desejosas deste apoio, independente de sua fé religiosa, de sua tradição espiritual. Nesse exercício de construção tem sido propostos como laboratórios, seminários anuais com temáticas diversas, ligadas à questão da saúde, abordadas sob diferentes óticas e tradições, que tem se mostrado momentos de rico compartilhamento e farol para uma prática coletiva que respeite as diferenças e aprenda com elas gerando respostas antes improváveis.
Do diálogo para o diálogo: o início do movimento adventista do sétimo dia e sua participação em diálogos interdenominacionais
Authors: Reis Douglas De Souza
Published: December 2018

Na efervescência do cenário religioso da América do Norte protestante no século XIX, o experimentalismo proporcionado por movimentos revivacionistas deu origem a diversos segmentos cristãos, entre os quais alguns se consolidaram como denominações, permanecendo até a contemporaneidade. O adventismo do sétimo dia, uma das facções do movimento interdenominacional conhecido como milerismo, surgiu como expressão do restauracionismo, propondo retorno radical à Bíblia. Seu início foi marcado pela tendência de evitar a organização formal, seguindo a máxima do milerita George Storrs, segundo quem, ao se organizar, um grupo religioso se tornava Babilônia. Entretanto, uma década após seu surgimento, nota-se o estabelecimento de um corpo doutrinário definido e alguns passos importantes rumo à organização, processo que culmina em 1861 com a escolha do nome Igreja Adventista do Sétimo Dia. Em suas primeiras décadas, os adventistas sabatistas permaneceram em diálogo com grupos afins, como demais epígonos do milerismo e os batistas do sétimo dia – enquanto outros intercâmbios se davam de maneira polêmica. Tão somente em meados do século seguinte, os adventistas dialogariam com o mundo evangélico, resultando na publicação do controverso material Questions on doctrine. A partir de então, outros diálogos interdenominacionais ocorreram, confirmando a vocação do movimento para interagir como o mundo cristão em geral.
SEMELHANÇAS E DISSONÂNCIAS EM ESPAÇOS DE ENSINAR E APRENDER
Authors: Pereira Eliane Regina , De Assis Neiva , Zanella Andrea Vieira , Maheirie Kátia
Published: December 2018

Este texto se propõe a fazer dialogar duas pesquisas que investigaram ações complementares ao ensino regular, de modo a dar visibilidade às semelhanças e às dissonâncias entre ONG e circo-escola. Ambas as pesquisas investigaram os sentidos produzidos por jovens sobre as atividades desenvolvidas para além dos muros escolares, dentro de serviços de ações complementares à escola. Tendo como referência as contribuições de Vygotsky e autores do círculo de Bakhtin, enfocamos neste texto a dimensão dos sujeitos que participam das ações complementares, as experiências tal como vivenciadas nessas atividades e os sentidos que jovens produzem sobre elas. Por meio de entrevistas com os jovens aprendizes e observações no cotidiano dessas ações, destacamos as relações nesses espaços mediadas pela afetividade e pelo aumento da potência de ser. Movimento afetivo-volitivo que permitiu aos aprendizes e jovens irem além de si mesmos, além do que estava posto, instituído. A relação entre educadores e jovens aprendizes mediou o aprender e necessariamente constituiu e constitui sujeitos que se fazem permanentemente aprendizes. Consideramos, à guisa de conclusão, ONG e circo-escola como espaços de potência para a criação e a recriação das relações de ensinar e aprender, fundamentalmente em virtude do modo como as linguagens artísticas são ali trabalhadas.
Relações de saber/poder no discurso de trabalhadoras cooperadas: relato do percurso metodológico
Authors: Girelli Scheila , Chalfin Coutinho Maria , Prado Filho Kleber
Published: December 2018

A produção do conhecimento no campo das Ciências Humanas e Sociais possibilita (re)construções teórico-metodológicas, considerando as diferentes visões de mundo que permeiam a relação entre os sujeitos. No que se refere às experiências relacionadas ao “mundo do trabalho”, as práticas ligadas ao movimento de economia solidária têm ganhado destaque, sendo alvo de constantes estudos. Dada sua heterogeneidade, desenvolveu-se uma pesquisa com o objetivo de compreender como se constroem as relações de saber/poder em uma cooperativa de costureiras inserida nesse movimento. Fruto do estudo, o presente artigo pretende apontar algumas reflexões sobre as possibilidades de o caminho metodológico adotado se constituir como uma estratégia qualitativa de pesquisa. Foram utilizados como procedimentos de pesquisa a observação participante ao cotidiano de trabalho, com registro em diário de campo, e a realização de grupos focais, a partir da fotografia. Os discursos das trabalhadoras foram analisados com base na Análise de Discurso. Como resultado, constatou-se que as relações cotidianas de trabalho são construídas num constante jogo de forças e contradições, revelando-se como um emaranhado de situações que vinculam, simultaneamente, formas de sujeição e laços afetivos. Estes garantem não só novos modos de gestão do trabalho que se aproximam da economia solidária, mas também a manutenção de velhas práticas enraizadas ao capitalismo. Conclui-se que, no percurso da investigação, o arsenal metodológico adotado constituiu-se como um valioso instrumento de pesquisa, capaz de possibilitar a compreensão do conjunto de enunciados presentes no discurso das trabalhadoras, considerando suas condições de produção.
Problemas de comportamento em crianças e adolescentes com falta de controle urinário noturno
Authors: Schoen Teresa Helena
Published: December 2018

A enurese é um problema que aflige muitas crianças. O objetivo deste estudo foi investigar a associação entre a falta de controle urinário noturno e problemas de comportamento. Participaram 774 pais de crianças e adolescentes de 5 a 18 anos, respondendo ao Child Behavior Checklist - CBCL. Foi selecionado o item “meu filho faz xixi na cama”, que foi comparado com os demais itens do instrumento e seus resultados. Verificou-se que 8,91% dos pais assinalaram positivamente este item. Houve associação entre falta de controle urinário noturno e idade, escolaridade - os mais novos, os que estudam nas séries iniciais do Ensino Fundamental e os com defasagem idade-série escolar -, e problemas de comportamento medidos pelo CBCL. Observou-se que ‘molhar a cama’ é um problema comum e pode levar a importantes distúrbios sociais e psicológicos. A implementação de uma triagem para problemas psicológicos pode contribuir para um melhor tratamento da enurese noturna.
Do we really know who are left behind and who are at risk of being left behind?
Authors: Elmusharaf Khalifa , Daboin Blanca Elena Guerriero , Crocetta Tania Brusque
Published: December 2018

There is enough evidence to show the importance of the first 1000 days of life for child survival and development, and the next 8000 days for a child to reach adulthood. Yet discrimination, place of residence, socio-economic status, and inequalities within and between countries contribute to earlier mortality and significant morbidities for mothers and their children, particularly in settings with limited resources. Therefore, many children and adolescents and their families were left behind.

JHGD has been raising public health issues related to inequalities and right to health. In this issue, articles generate debate around human dignity and health disparities. Several articles discuss a verity of health issues particularly in Amazon and Northeast region. School health was also discussed in this issue. Three studies were conducted in schools in Rio Grande do Sul, Brazil.

Research indicate that many children and adolescents are left behind. We are missing many opportunities to bridge the gap of inequality. Actions need to be taken now to make sure no one is left behind.
Effect analysis of environmental factors on the children’s Amazon community neuropsychomotor development
Authors: Pantoja Ana Paula Pureza , Souza Givago Da Silva , Nunes Erica Feio Carneiro , Pontes Lucieny Da Silva
Published: December 2018

Introduction: The early years of a child’s life are marked by a significant development, as well as high sensitivity to environmental influences such as poverty, housing, quality and family structure. Thus, the identification of environmental risk factors and delayed neurodevelopment, coupled with early intervention, are essential for an healthy development.

Objective: To analyze the effect of environmental factors on the neuropsychomotor development of children in the Amazon community.

Methods: This is a quantitative and qualitative study of analytical and cross-sectional approach with 50 children between 24 and 36 months of age, of both sexes, living in an Amazonian community. Two types of the socio-economic-environmental questionnaire were used; a) Infant/Toddler (IT) HOME Inventory to analyze the quality of the family environment; b) the Denver Screening Test II for screening neurodevelopment. Also, a descriptive analysis was performed using a calculation of means and standard deviations.

Results: The study found that a significant majority of the children had normal neuropsychomotor development; however, children classified as delayed, the more significant impact variable in the development was the quality of the family environment, which in turn was influenced by the lower economic class, lack of water treatment, lack of electricity and external toilet.

Conclusion: Environmental factors were not significant on the neuropsychomotor development of the local children of the Amazon community.
Nurturing resilience: the ‘ordinary magic’ of everyday life
Authors: Roiste Ảine De
Published: December 2018

A brief exploration of resilience and child development is presented. The concepts of resilience and ‘risk competence’ are elaborated on along with some of the practice implications of these with respect to child care and wellbeing. Questions are raised regarding managing childhood risks while at the same time enabling children to become capable in assessing and handling risks themselves.
Evaluation of the Patient Safety Culture in the Western Amazon
Authors: Silva Glauco M. da , Lima Marcos V. M. de , Araripe Marcos C. , Vasconcelos Suleima Pedroza , Opitz Simone Perufo , Laporta Gabriel Z.
Published: December 2018

Introduction: The safety culture of the patient is a contributing factor for the maintenance of the user’s well-being in the health system because, through it, an organized systematization and quality of patient care are obtained, preventing possible intercurrences that can cause damages.

Objective: To analyze the Patient Safety Culture (PSC) from the perspective of health professionals at the Reference Hospital of the Upper Juruá River, in the Brazilian Western Amazon.

Methods: This is a cross-sectional study developed in a medium-sized public hospital in a municipality in Western Amazonia. The Survey for Patient Safety Culture survey of the Agency for Healthcare Research and Quality was applied to 280 professionals from December 2016 to February 2017. Descriptive analysis of the data and the internal consistency of the instrument were performed.

Results: The results indicate the best evaluations in the dimensions of Teamwork in the scopes of the units (60%) and Organizational learning (60%). The aspects with the worst results were the dimensions of non-punitive responses to errors (18%) and frequency of events reported (32%). The internal reliability (Cronbach’s Alpha) analysis of the dimensions ranged from 0.35 to 0.90.

Conclusion: The "culture of fear" seems to predominate in this hospital, however, the study showed that there is scope for improvement in all dimensions of CSP. The values of Cronbach’s Alpha presented similarity to the results obtained by the validation process.
United States National Postdoc Survey results and the interaction of gender, career choice and mentor impact
Authors: McConnell Sean C , Westerman Erica L , Pierre Joseph F , Heckler Erin J , Schwartz Nancy B
Published: December 2018

The postdoctoral community is an essential component of the academic and scientific workforce, but a lack of data about this community has made it difficult to develop policies to address concerns about salaries, working conditions, diversity and career development, and to evaluate the impact of existing policies. Here we present comprehensive survey results from 7,603 postdocs based at 351 US academic and non-academic (e.g. hospital, industry and government lab) institutions in 2016. In addition to demographic and salary information, we present multivariate analyses on factors influencing postdoc career plans and satisfaction with mentorship. We further analyze gender dynamics and expose wage disparities. Academic research positions remain the predominant career choice, although women and US citizens are less likely than their male and non-US citizen counterparts to choose academic research positions. Receiving mentorship training has a significant positive effect on postdoc satisfaction with mentorship. Quality of and satisfaction with postdoc mentorship also appear to heavily influence career choice.
Effects of dietary supplementation with Lactobacillus acidophilus on the performance, intestinal physical barrier function, and the expression of NOD-like receptors in weaned piglets
Authors: Wang Shiqiong , Li Haihua , Du Chenhong , Liu Qian , Yang Dongji , Chen Longbin , Zhu Qi , Wang Zhixiang
Published: December 2018

Lactobacillus supplementation is beneficial to the barrier function of the intestinal physical barrier in piglets. However, the mechanisms underlying this beneficial function remain largely unknown. Here, we investigated the effects of dietary supplementation with Lactobacillus acidophilus on the performance, intestinal physical barrier functioning, and NOD-like receptors (NLRs) expression in weaned piglets. Sixteen weaned piglets were randomly allocated to two groups. The control group received a corn-soybean basal diet, while the treatment group received the same diet adding 0.1% L. acidophilus, for 14 days. As a result, dietary L. acidophilus supplementation was found to increase the average daily gain (ADG) (P < 0.05), reduced serum diamine oxidase (DAO) activity (P < 0.05), increased the mRNA expression and protein abundance of occludin in the jejunum and ileum (P < 0.01), reduced the mRNA levels of NOD1 (P < 0.01), receptor interacting serine/threonine kinase 2 (RIPK2) (P < 0.05), nuclear factor κB (NF-κB) (P < 0.01), NLR family pyrin domain containing 3 (NLRP3) (P < 0.01), caspase-1 (P < 0.01), interleukin 1β (IL-1β) (P < 0.05) and IL-18 (P < 0.01) in the jejunum tissues of the weaned pigs. The expression of NLRP3 (P < 0.05), caspase-1 (P < 0.01), IL-1β (P < 0.05) and IL-18 (P < 0.05) was also reduced in the ileum tissues of the weaned pigs. These results showed that L. acidophilus supplementation improves the growth performance, enhances the intestinal physical barrier function, and inhibits the expression of NOD1 and NLRP3 signaling-pathway-related genes in jejunum and ileum tissues. They also suggest that L. acidophilus enhances the intestinal physical barrier functioning by inhibiting IL-1β and IL-18 pro-inflammatory cytokines via the NOD1/NLRP3 signaling pathway in weaned piglets.
A PESQUISA NA FORMAÇÃO INICIAL DOCENTE NO BRASIL E NA ARGENTINA
Authors: Cordeiro Bobato Francine , Domingues Ferreira Paloma
Published: December 2018

O presente trabalho é resultado de uma investigação que analisou o lugar da pesquisa na formação inicial docente para atuação nos primeiros anos no Brasil e na Argentina. Assim, na intenção de compreender, verificar e interpretar, na perspectiva comparada, como esses países articulam a pesquisa no processo de formação de professores, o estudo de cunho bibliográfico fez uso dos caminhos metodológicos da Educação Comparada. A pesquisa revelou a partir do escopo legislacional, que ambos os países explicitam recomendações e indicativos a respeito da importância e necessidade da pesquisa na formação docente. Contudo, a realidade dos espaços formativos nos países em tela apresenta, no contexto da prática, diferentes entendimentos, bem como distintas possibilidades da pesquisa no processo formativo incluindo até mesmo sua ausência.
Sarcoidosis of the breast: an unusual clinical presentation
Authors: Carvalho Jozélio Freire , Ramos Cleófano Lima , Ramos Paulus Mascarenhas , Oliveira Virginia Freitas de Sá , Araujo Danilo Barral de
Published: December 2018

Introduction: Sarcoidosis is a chronic systemic granulomatous disease of unknown etiology. The breast may be involved in less than 1% of cases and often mimics carcinomas at clinical examination.  Case report: Herein, the authors report a 54-year-old woman who had history of erythema nodosum, had clinical presentation suggestive of mastalgia whose mammography and ultrasound showed bilateral unspecific heterogeneous parenchymal densities. Histopathological study revealed non-caseous giant cell granulomas. Specifically, serum levels of angiotensin-converting enzyme (ACE) were elevated and a CT scan showed small bilateral pulmonary nodules distributed along the pleura and bronchovascular bundles (perilymphatic pattern), however without enlarged bilateral hilar and mediastinal lymph nodes. The patient was treated with prednisolone and methotrexate, and is currently asymptomatic. Conclusion: Breast involvement by sarcoidosis, although rare, should be considered when dealing with granulomatous lesions of the breast.
Uso de marcadores fluorescentes na engenharia tecidual óssea: estudo piloto
Authors: Dourado Raisa Cavalcante , Rolim Ana Emília Holanda , Rosa Fabiana Paim
Published: December 2018

Introdução: a regeneração e o reparo de tecidos ósseos perdidos é objeto de estudo da Bioengenharia Tecidual. O uso de biomateriais substitutos ósseos biomiméticos visa estimular os sistemas celulares e bioquímicos para restabelecer de modo mais eficiente o tecido ósseo nos casos de sua reconstrução. Ao investigar o processo de remodelação, é vital identificar áreas de novo crescimento para avaliar a eficácia dos biomateriais implantados e respectivos regimes de tratamento. A avaliação qualitativa e quantitativa da regeneração óssea pode ser realizada através da aplicação de marcadores como o Xilenol, a Tetraciclina, a Calceína e a Alizarina. A administração desses marcadores de forma associada possibilita ainda marcar sequencialmente camadas de nova deposição e remodelação durante o reparo.  Objetivo: estabelecer um protocolo para utilização dos marcadores fluorescentes de reparo ósseo xilenol, tetraciclina, calceína e alizarina, em ratos. Método: foram utilizados 35 ratos da linhagem Wistar, machos adultos, com massa corpórea entre 350 e 400g, e idade aproximada de 4 a 5 meses, distribuídos randomicamente em 5 grupos experimentais, submetidos à confecção de defeito ósseo circular de 8 mm em região de calvária, e administração dos diferentes marcadores segundo os grupos; XO - Xilenol; Ca - Calceína; Al - Alizarina; Te – Tetraciclina; C - Controle. Após 15 dias de experimento, os animais foram eutanasiados e as calvárias processadas e analisadas por histomorfometria, microscopia de epifluorescência e microscopia de fluorescência. Resultados: todos protocolos empregados para utilização dos marcadores fluorescentes xilenol, calceína, alizarina e tetracicilina foram úteis para identificar área de deposição mineral durante o período analisado de regeneração óssea em ratos. As imagens obtidas pela microscopia de fluorescência revela a presença dos marcadores incorporados à matriz óssea neoformada, no entanto a utilização da Alizarina e Calceína dentro dos protocolos testados mostraram-se mais eficientes. Conclusão: os protocolos testados nesse estudo apresentaram-se viáveis para utilização em pesquisas envolvendo marcadores de regeneração óssea, com resultados  superiores para Alizarina e Calceína.
Análise descritiva dos índices de morbidade e mortalidade de pacientes com cardiopatia reumática crônica em Salvador, Bahia, Brasil
Authors: Sarraf Emmanuelle Melo , Barros Rafael Damasceno de , Ribeiro Nildo Manoel Da Silva
Published: December 2018

Introdução: a cardiopatia reumática crônica (CRC) é a manifestação clínica de maior relevância da febre reumática (FR). É a causa mais comum de insuficiência cardíaca na população infantil e em adultos jovens. Objetivo: descrever os índices de morbimortalidade em pacientes com cardiopatia reumática crônica em Salvador, Bahia, Brasil. Metodologia: trata-se de um estudo ecológico de série temporal com dados secundários, sobre os índices de morbimortalidade de usuários com doenças reumáticas crônicas do coração, entre o período de 2008 até o ano de 2017, em Salvador, Bahia, Brasil. Resultados: foi observada uma maior ocorrência de internações e mortalidade em pacientes do sexo feminino. Houve uma maioria de óbitos entre os maiores de 60 anos. De acordo com a raça, internações e óbitos predominaram na população parda, em Salvador (BA), enquanto a cor da pele branca predominou nas ocorrências da população brasileira. Conclusão: embora seja observada uma redução nos índices de morbidade e mortalidade dos pacientes com cardiopatia reumática crônica quando comparados com os de anos anteriores, ainda é necessário investir em políticas de saúde para prevenção e controle dessa doença, visto que ela representa um impacto importante nos custos financeiros do Sistema de Saúde.
Symmetrical organization of proteins under docked synaptic vesicles
Authors: Li Xia , Radhakrishnan Abhijith , Grushin Kirill , Kasula Ravikiran , Chaudhuri Arunima , Gomathinayagam Sujatha , Krishnakumar Shyam S. , Liu Jun , Rothman James E.
Published: December 2018

During calcium‐regulated exocytosis, the constitutive fusion machinery is ‘clamped’ in a partially assembled state until synchronously released by calcium. The protein machinery involved in this process is known, but the supra‐molecular architecture and underlying mechanisms are unclear. Here, we use cryo‐electron tomography analysis in nerve growth factor‐differentiated neuro‐endocrine (PC12) cells to delineate the organization of the release machinery under the docked vesicles. We find that exactly six exocytosis modules, each likely consisting of a single SNAREpin with its bound Synaptotagmins, Complexin, and Munc18 proteins, are symmetrically arranged at the vesicle–PM interface. Mutational analysis suggests that the symmetrical organization is templated by circular oligomers of Synaptotagmin. The observed arrangement, including its precise radial positioning, is in‐line with the recently proposed ‘buttressed ring hypothesis’.