bluuebunny/crossref_metadata_2025 huggingface dataset:
高校管理会计课程改革的探讨
Authors: 罗 娟
Published: November 2019

经济的不断攀增就对会计工作提出越来越严格的要求,且会计专业是一种传统专业,在当今高职院校教育新兴的模式之下,不管是会计专业的教育理论、培养方式、教学环节等都与时代发展严重不符。随着人工智能的发展,传统的财务会计岗位将被智能化软件替代,管理会计是目前会计专业转型的新方向。基于此,文章就高职院校管理会计课程改革进行探讨。
体育教学中如何对智障学生进行运动康复训练
Authors: 张 聪
Published: November 2019

体育运动康复训练是治疗智障学生感觉失调的有效康复方法之一,作为针对人体感觉器官的一种训练康复方法,主要机理是影响感觉器官,后让心理产生与之相应的变化,有效开发智障学生智力。本文主要以辽宁省大连市特殊教育学校智障学生运动康复训练为例,在系统阐述智障学生体育教学运动康复训练原则的基础上,深入分析了体育运动康复训练方法,进一步探讨了提高体育运动康复训练质量提高良策。
刍议微课在高中英语教学中的应用
Authors: 黄 凌
Published: November 2019

微课是现代化的教学形式,微课凭借信息化的教学技术,短小精悍的教学内容,创新灵活的展示形式得到了高中英语教学的青睐。当前高中英语课堂教学广泛地使用微课教学形式,还要进一步创新微课用于高中英语教学的方法,解决传统英语课堂教学的弊端,全面提高微教学有效性。
区域活动中促进幼儿认知能力发展的观察研究——以益智区、建构区为例
Authors: 杨 娟 , 于 艺
Published: November 2019

幼儿认知发展是在与真实世界的积极互动中,通过主动学习获取的。区域活动对幼儿认知能力的发展具有重要价值,幼儿通过操作材料、自由探索,在与环境、同伴和教师的互动中获得认知和理解。研究者通过实地观察,深入了解幼儿在区域活动中的认知能力表现,如注意力、记忆力、思维力、想象力等,同时以CLASS评价系统为基础探讨教师有效指导的策略,提高区域活动中师幼互动的质量。
建筑手绘艺术微项目学习在高校陈设类课程中的实现途径
Authors: 贾 思怡
Published: November 2019

建筑手绘艺术是陈设分项之一。针对目前陈设类课程出现的具体问题,结合项目学习、微资源、微课堂等各种“微”理念的理解,克服项目学习原有缺点,提出“微项目学习(MicroProject)”的概念。“微项目学习”实质上是项目学习的灵活运用,使得项目学习简化、微型化,让课堂学习更高效、灵活、实用。本文阐述了微项目学习的具体方法和优点,并做出了一系列的教学设计,对微项目学习在高校陈设类课程教学中进行实际运用,从而提高了教学效果。
“一带一路”快车上“义乌进博会”的溢出效应和辐射效应研究
Authors: 邓 建兵
Published: November 2019

“一带一路”快车上“义乌进口博览会”将通过丰富的高端经贸论坛、国际展和企业展彰显中国主动开放市场,构建开放型的经济姿态。本文将基于上海进博会的溢出效应,及义乌正处于义乌国际贸易综合改革试验区重要建设时期,提出“义乌进博会”树立引领义乌小商品全球贸易发展的新风向标、“义乌进博会”构建推进义乌开放型发展的新平台、“义乌进博会”打造促进义乌国际贸易综合改革试验区建设的新高地,以期通过“义乌进博会”辐射效应推动义乌高水平开放、高质量发展迈向新台阶。“义乌进博会”通过进口“一带一路”沿线国家和地区的高质量新商品,让世界分享中国经济的红利。通过引进“一带一路”沿线国家和地区的高新技术,倒逼义乌相关企业对产品和技术创新,生产更多更高质量的小商品以满足了中国人民对美好生活的向往。
以创客文化为视角的高校双创教育探究
Authors: 徐 微
Published: November 2019

新时期背景下我国各行各业都得到了快速发展,为创业者提供了良好的环境。众多创业者聚集在一起进行探讨和创新,进而形成了创客文化。将创客文化引入到高校双创教育中,不仅有助于社会创新创业影响力的提高,更能够在创客文化的影响下促进高校双创教育的深入发展。在高校不断深化教育改革的背景下,我们需要借助创客文化价值的发挥来促进高校双创教育改革的深入实施。本文以创客文化为切入点,论述了创客文化应用到高校创新创业教育中的价值,然后提出了以创客文化为视角的高校创新创业教育的开展策略。希望能够从理论研究层面更好地指导高校双创教育的开展,为社会培养更多优秀的人才。
从认知角度分析诗词中“花开”“花落”蕴含的隐喻
Authors: 宋 娟
Published: November 2019

随着认知语言学的发展,隐喻已被认为是重要的认知手段和思维方式。本文从认知的角度来分析诗词中的“花开”“花落”所隐喻的内容,以使人们在阅读诗词时,能更好地体会和理解其中所蕴含的情感因素。
浅析新时期档案管理工作中存在的问题及对策
Authors: 朱 明月 , 于 丽
Published: November 2019

随着新时代发展步伐的加快,高校档案管理工作在日常工作的科学化、制度化、常态化,以及硬件条件的不断完善和管理理念革新上,都有了大幅度的提升,但也仍然存在一些有待解决的问题,而正是这些新、旧问题直接影响和制约了高校档案管理工作的快速发展。本文就存在的问题及解决对策进行了深入的探讨,对如何提升档案管理工作的效率,使其更好地适应现代化社会发展的需要阐述了不同的见解。
“课程思政”新视角下高职社区护理课程教学改革的探究
Authors: 侯 赛宁 , 顾 迎春 , 马 琼 , 关 丽丽 , 张 敏 , 王 晓君
Published: November 2019

本文以“课程思政”的育人理念为背景,分别从高职社区护理课程的课程定位、高职社区护理课程思政元素的挖掘依据、高职社区护理课程拟定相关教学案例,同时围绕实践教学存在问题及解决途径进行深入思考。探索如何在专业知识与技能培养的同时,实现传授知识与价值观引领的有机统一,从而真正达到了以立德树人为导向,坚持全员、全过程、全方位育人的昀终目标。
Synthesis and Antifungal Study of Some Acetophenone Oximes and Their Terphthaloyl Oxime Esters
Authors: Ali Bawa Ramadan , Mohammed Friwan Mona
Published: November 2019

Acetophenone oximes 1 – 5 along with their terphthaloyl oxime esters 6 – 10 have been synthesized in moderate to good yields. Only one oxime was formed in as E/Z two isomers in a ratio of (8:1). These resulting oxime derivatives were involved in an antifungal screening against the Aspergillus niger at concentration of 30 ppm. Two commercially available antifungal agents, clorotimazole and daktarin, were employed as references at the same concentration, 30 ppm. The antifungal results for the oxime derivatives 1 – 10 showed inhibitory levels ranging from 38% to 100%, whereas the antifungal potentials for the two references were found to be ~ 63% and 68% for clorotimazole and daktarin respectively.
Finite Element Simulation of Acceleration Pedal On XX Vehicle
Authors: Sutisna Nanang Ali , Hardianto Aldhito
Published: November 2019

This paper presents the failure analysis of acceleration pedal of xx vehicle. The purpose of this research are to know the cause of failure, types of failure, and approach in searching for the best parameters that yield optimal product quality on product design. This research uses the known test method, where the type of failure and results of analysis compared with the result of expected product reliability. The simulation uses CATIA V5 software involving types of load that applied on product, length, size and dimension of product, and types of material. Simulation result data is used for see the influence and effect of each parameter to the product design, also the types of failure that will affect the product reliability
PROGRAM EXCELLENCE SOLUTION UNTUK MENURUNKAN WAKTU PENGERJAAN REMANUFACTURING UNIT KOMATSU PC2000-8 DI PT UT SITE KALIMANTAN SELATAN
Authors: A.T. Manurung Vuko , Pama Deprian Lukyawan , Tri Joko Wibowo Yohanes
Published: November 2019

With the passage of time the heavy equipment unit will experience a decrease. In order to return the unit to its initial performance, the Reman manufacturing process is abbreviated as Reman. Reman is an activity carried out to keep heavy equipment units close to performance when first created.

PT UT site Adaro is trusted by its customers to do Reman specifically for Komatsu PC 2000-8 type excavators. In the implementation there was a delay in the implementation of the work process to 80 days. Therefore, a program was created to reduce the total leadtime to 45 days or down by 44%.
Kadar HbA1c pada Pasien Wanita Penderita Diabetes Mellitus Tipe 2 di Rsud Dr. Doris Sylvanus Palangka Raya
Authors: Sartika Fera , Hestiani`` Nurul
Published: November 2019

Laboratory tests recommended by the ADA as a supportive examination for diagnosing DM are Hemoglobin Adult 1C (HbA1c), HbA1c examination can be used as a reference for monitoring diabetes mellitus because HbA1c can provide clearer information about the true condition in people with diabetes mellitus. HbA1c examination is an examination that reflects the average blood glucose level over a period of 2-3 months. The purpose of this study was to determine the description of HbA1c in female patients suffering from type 2 diabetes mellitus in RSUD dr. Sylvanus Palangka Raya. This research was conducted using a cross sectional study method with accidental sampling technique. The sample used in this study was patients suffering from type 2 diabetes mellitus in RSUD dr. Doris Sylvanus Palangka Raya taken by 15 people. Then examined using the boronate affinity method. The results obtained by the HbA1c category were 4 people (26.67%) good, 6 people (40%) medium and 5 people (33.33%) bad.
The Potential of Walnut Seeds (Canarium indicum L.) in Repairing The Genotoxicity Effect of Mercury on Mice Erythrocytes
Authors: Wibowo Cakra Haryo , Oktarina Essy , Wardani Rafika Destiana , Ngibad Khoirul
Published: November 2019

Hydrargyrum (familiar as mercury) is a persistent transition metal element. They are known as bio-accumulative properties that are dangerous to the environment and has serious damaging effects on biota, including genetic changes or mutagenesis. Moreover, it can accumulate indirectly in the human body due to the consumption of products that have contaminated. Whereas, ellagic acid has reported as one of 13 flavonoid compounds that have potential as an anti-mutagen and anti-cancer in the walnuts seeds. This study was aimed to ensure the potential extent of ellagic acid extracts in walnut seeds to reducing and repairing the genotoxicity effects of mercury. Therefore, using the experimental method, this study was divided into several test treatments. Two controls treatment as a comparison of the presence of micronucleus with group tests that given a 20 ppm mercury dosage. Then continued with the addition of walnut seed extract with various dosage (10, 15, and 20 ppm) by oral injection continuously for two weeks as a recovery process to reducing and repairing the genotoxicity effect of mercury. The significant results showed that there are differences between pre and post-treatment. It indicated that the extract has the potential for improving and reducing the genotoxicity effect of mercury. The data were evaluated and obtained the total micronucleus from the smear of peripheral blood of mice by comparing the total micronucleus before and after giving of walnut extract.
Quantitative Analysis of Caffeine Levels in Local Coffee (Coffea sp) Powder on Dabo Island with UV-Vis Spectrophotometry
Authors: Hainil Sri , Suhaera Suhaera , Lirtri Lirtri
Published: November 2019

Coffee (Coffea sp) is the second-largest beverage consumed by people around the world whose process comes from the processing and extraction of coffee beans. Coffee has a chemical compound, one of which is caffeine. Caffeine is a crystal-shaped compound. Caffeine can be a tangible white powder or a shiny white needle-shaped, odorless caffeine, and caffeine has a bitter taste. The purpose of the study was to determine the caffeine levels of local ground coffee on the island of Dabo with the spectrophotometry UV-Vis method. Analysis of the ground coffee caffeine levels is quantitative determined using spectrophotometry UV-Vis. The equation of the calibration curve of caffeine is regression y = 0.1307x + 0.0112 with a correlation coefficient value (r) of 0.9993. Based on Indonesian National Standards (SNI) 01-7152-2006, The maximum limit of caffeine in foods and beverages is 150 mg/day and 50 mg/serving. The results of the analysis of caffeine levels from three samples of ground coffee circulating on Dabo Island each in 2 g were 0.3383 mg for Sample A; 0.3786 mg for Sample B; and 0.5803 mg for Sample C.
Active Fractions of Methanol Crude Obtained from Acacia seyal gum: Antioxidant Capacity, using FTIR Analysis
Authors: Elnour Ahmed Adam M , Mirghani Mohamed Elwathig Saeed , Kabbashi Nassereldeen A , Alam Md Zahangir , Musa Khalid Hamid
Published: November 2019

The present study is on Acacia seyal gum (ASG), which is an exudate from Talha tree. It provides a rich source of polyphenolics compounds that are used traditionally in folk medicine. The study aims to determine the antioxidant capacity (AC) and functional groups of ASG and Prebio-T-commercial (PTC) samples. The methanol crude extracts of both ASG and PTC have fractioned into chloroform (CHF), hexane (HF), acetone (AF) and methanol (MF) using solvent-solvent portion. Both ferric reducing antioxidant power (FRAP), and cupric reducing antioxidant capacity (CUPRAC) assays for each fraction examined. Crude methanol extracts (CME) and its active compositions also analysed carefully using Fourier Transform Infrared Spectroscopy (FTIR) technique. The findings presented a wide variety of functional groups provided by the FTIR spectra (eights bands approximately. Regarding cupric reducing antioxidant capacity (CUPRAC), the methanol crude extracts values are 888.6�4.57 mg TE/100g extract, for PTC as compared to 474.3� 2.23 mg TE/100g of extract for ASG. However, both methanol and acetone fractions revealed significantly (p = 0.05) high FRAP values ranged between 599.8�7.5 and 741.8�5.8 mg TE/100g fraction; for PTC and ASG, respectively. While CUPRAC showed insignificant (p = 0.05) same values 356.1�2.62 mg TE/100g of fraction; for MF of both PTC and ASG respectively. Therefore, in this study, methanolic fractions (MFs) are found to be more effective than acetone fractions (AFs), except for CHF and HF. Finally, the antioxidant activity of the active fraction has provided some evidence regarding its functional groups which may have used in traditional medicine.
Implementation of Absolute Priority in a Predictive Traffic Actuation Schemes
Authors: Boudhrioua Souhir , Shatanawi Mohamad
Published: November 2019

Nowadays, the improvement of the emergency vehicles' priority is required to improve their response time. Presently, the emergency vehicles alert the road users using the sirens and lights, which might cause disturbances in the traffic or lead to accidents due to the unpredictability of the road users' behaviors. This paper introduces the priority indicator, which calculates the priority of several emergency vehicles as they approach an intersection and sort them in a way that allows granting priority to each one without causing delays neither for the emergency nor for the normal vehicles. The priority indicator is then introduced in a predictive traffic actuation program (DIRECTOR) that adjusts the signal timing in a dynamic way. Thus, this research aims to create a generalized priority form that simplifies granting the priority for emergency vehicles in a harmonized way in all over the Netherlands, making sure that it takes into consideration the several conditions of the intersection.
Contemporary Concepts of Inclusive Education in North American and Ukrainian Studies
Authors: Nakonechna Larisa
Published: November 2019

Nowadays in Ukraine there is a dynamic progress in the dissemination of inclusive education. It determines the need to study and adapt the experience of other countries, taking into account the specifics of domestic realities. Of special interest are the countries of North America, in particular Canada and the United States, which have
a fairly long history of inclusive education. The comparative analysis will enable us to identify the possibility of applying the most effective strategies of inclusion in the educational system of Ukraine Nowadays, in Ukraine, there is a certain dynamic progression of inclusive distribution. It is this that actualizes the need to study and use
the experience of other countries, taking into account the specifics of domestic realities. Amid existence of a number of concepts of inclusive education in the world of educational space different approaches are distinguished in the methodological framework. Comparing the essential understanding of these approaches in North American and Ukrainian educational systems, there is unanimity of views in common positions. However, there are certain differences, particularly in recognizing the SEN position of the child as subject and object in the system: Western inclusive education system is fully regulated by law, while in Ukraine there is a gradual overcoming of the philanthropic vestiges through the expansion and improvement of the legal framework with the underlying international instruments. Awareness of the position of individual approach as the cornerstone of an inclusive education system in both educational scientific communities generally coincides. Unity of scientific views of North American
researchers and Ukraine is also observed in the vision of status and role positions of all participants in inclusive education as a prerequisite for regulatory functioning education system. Unanimous scientists of both scientific schools and the professional competence of teachers as a key tool for coordinated activities in the inclusive class
and the functioning of the educational system as a whole. The definition of common components and specific features of the development of inclusive education on the basis of ideological interpretations will help to determine the general character of the grounds for the inclusive form of education and to use the positive experience of
Western countries in Ukrainian realities effectively.
Repeated Exposure to Hyperbaric Hyperoxia Affects Mitochondrial Functions of the Lung Fibroblasts
Authors: DEJMEK J. , KOHOUTOVÁ M. , KRIPNEROVÁ M. , ČEDÍKOVÁ M. , TŮMA Z. , BABUŠKA V. , BOLEK L. , KUNCOVÁ J.
Published: November 2019

Hyperbaric oxygen (HBO) therapy, i.e. breathing pure oxygen under increased environmental pressures serves as a treatment for diverse medical conditions. However, elevated oxygen concentration can be detrimental to central nervous system or lungs. Our study aimed to evaluate the effects of repeated exposure to HBO on mitochondrial respiration assessed by high-resolution respirometry (HRR), cell viability estimated by PrestoBlue® reaction, morphology analyzed by routine phase contrast and fluorescent microscopy, and superoxide dismutase (SOD) and citrate synthase (CS) activities using human lung fibroblasts. The cells were exposed to HBO for 2 h per day for 5 consecutive days. One day after the last exposure, HBO cells displayed significantly smaller area and perimeter, compromised viability and elevated SOD activity. No changes were detected in CS activity or quality of mitochondrial network. HRR revealed impaired mitochondrial oxygen consumption manifested by increased leak respiration, decreased activity of complex II and compromised ATP-related oxygen consumption when fatty acids were oxidized. Our findings document that in conditions mimicking chronic intermittent exposure to HBO, lung fibroblasts suffer from compromised mitochondrial respiration linked to complex II and impaired cellular growth in spite of increased antioxidant defense. Underlying mechanism of this HBO-induced mitochondrial dysfunction should be further explored.
Rebecca West, the Forgotten Vorticist?
Authors: Mourant Chris
Published: November 2019

The inclusion of Rebecca West's short story ‘Indissoluble Matrimony’ in the first issue of BLAST (1914) has much to tell us about the intellectual debts the Vorticist movement owed to West and to the feminist periodical culture with which she was associated. West composed her story in 1912–13, years when she was highly active as both contributor to and literary editor of Dora Marsden's The Freewoman (1911–12) and The New Freewoman (1913). In this article, I examine how the ‘energy’ promoted across BLAST aligned with feminist political conceptions of energy in Marsden's journals, and how these ideas were also shaped by early twentieth-century understandings of the universe, including theories of vortex motion, the ether, electromagnetism and thermodynamics. By paying close attention to the theme and metaphor of energy in ‘Indissoluble Matrimony’, this article traces patterns of influence between West, Marsden, Ezra Pound and Wyndham Lewis that reveal intersections between avant-guerre feminism and the Vorticist avant-garde.
Compton Mackenzie's and Hugh MacDiarmid's Early Broadcasting Critique: Vox, Modernism, and the BBC
Authors: Puymbroeck Birgit Van
Published: November 2019

This article recovers Compton Mackenzie's little-known radio journal Vox, The Radio Critic and Broadcasting Review for critical consideration, and shows that, through Vox and through their own radio broadcasts, Mackenzie and Hugh MacDiarmid (who acted as managing editor of Vox) advocated regional variety and independence. It builds on recent approaches to regional modernism, demonstrating how Vox resisted a national framework, and reads Mackenzie's critical journal in dialogue with MacDiarmid's modernism.
PENINGKATAN RESOLUSI SENSOR LOAD CELL PADA TIMBANGAN ELEKTRONIK
Authors: Mandayatma Eka
Published: November 2019

Electronic scales are heavy gauges that are widely used both in the laboratory and in the business world. One of the main sensors of electronic scales is the load cell. The direct use of load cell will result in the achievement of the standard resolution of the load cell or ADC system used, so the resolution of the scales will be quite low as it is determined only by the load cell measurement range and the ADC resolution where the dynamic range of the ADC is not reached.In this article will be made electronic efforts to increase the resolution of the scales so that the accuracy of weighing can be better. Improved resolution attempts are made with electronic signal processor and conditioners, among others, by amplifying, summing and leveling amplifiers and to prevent noise being attempted by filtering. Data processing is done by comparing the resolution value of Load cell without signal conditioner and load cell resolution with signal conditioner. Load Cell with a load range of 0 - 5 kg in conditioning with 200x gain obtained output 113 mV to 1200 mV. With a standard ADC at a resolution of 20 mV / bit will be obtained 0000 0110 to 0011 1110 By adding a Leveling Amplifier circuit obtained output 48 mV for load 0 kg and 4.87 Volt for 5 kg load, ADC output in the range 0000 0010 to 1111 1100. Usage ADC without leveling 21% and with 98% leveling. Without leveling weighing resolution is 89 grm / bit and with 20 grm / bit leveling. Increased weighing resolution of 345%.
KAJIAN EFISIENSI ENERGI DENGAN PENGATURAN SUPLAI ENERGI LISTRIK
Authors: Mieftah Mochammad
Published: November 2019

A power system can be said to be reliable if it has a high continuity of service. To achieve this, an operational arrangement is required to optimize installed power to supply the load to avoid overloading or over-supply of the system. Modjopanggoong Sugar Factory Tulungagung is one of the sugar producing industries, where the electrical system in this factory uses two power supply, which is using PLN supply and Turbine Generator Boiler (BTG). The use of more than one power supply resulted in an increase in the required electricity production costs. To solve this problem, in this research will be conducted a study to make efficient of electrical energy cost which is done by arranging supply of electric energy, that is using maximum supply of BTG and its deficiency supported PLN supply (alternative I), using PLN maximum supply and its deficiency is supported BTG supply alternative II) and only use PLN supply (alternative III). The results showed that energy efficiency can be done with the regulation of energy supply at the factory, that is in alternative I with savings Rp.430.025.007 (2.1%), alternative II with savings of Rp. 553,984,815 (2.7%), and alternative III with savings of Rp. 2.055.727.407 (10%).
Relationship between Nutrition Deficiency, Oral Cavity Hygiene, and Oral Candidiasis in a 10-Years-Old Child
Authors: Hernawati Sri
Published: November 2019

Candida albicans (C.albicans) is the main causative agent in oral candidiasis. Candida spp is a commensal microorganism or normal flora in the mouth without causing symptoms. Candida spp can be a pathogen when the body's condition decreases, systemic medical therapy for a long time, nutritional deficiencies and poor oral hygiene. This study aimed to determine the predisposing factors for the causes of oral candidiasis in 10-year-old pediatric patients who came to the Department of Oral Medicine, Dental Hospital of Dentistry Faculty of Jember University. The results of this study indicate a relationship between nutritional deficiencies and poor oral hygiene with oral candidiasis in children. White pseudomembranous plaque lesions are mostly found in the dorsal area of the tongue. Therapy for the patients is by applying nystatin anti-fungal, multivitamins, and education to improve nutrition and oral hygiene.

Keywords: nutritional deficiency; the oral cavity hygiene; oral candidiasis
Effects of Temperature on the Characteristics of Nitrogen Removal and Microbial Community in Post Solid-Phase Denitrification Biofilter Process
Authors: Zhang Qian , Chen Xue , Luo Wandong , Wu Heng , Liu Xiangyang , Chen Wang , Tang Jianhong , Zhang Lijie
Published: November 2019

In order to solve the problems of high energy consumption, complex process and low nitrogen removal efficiency in the currently available low carbon source wastewater treatment processes, a novel coagulation sedimentation/post-solid-phase denitrification biofilter process (CS-BAF-SPDB) was proposed. The effect of temperature on the nitrogen removal performance of BAF-SPDB was intensively studied, and the mechanism of the effect of temperature on nitrogen removal performance was analyzed from the perspective of microbial community structure by using the polymerase chain reaction denaturing gradient gel electrophoresis (PCR-DGGE). The results showed that, to realize favorable nitrifying and denitrifying performance simultaneously in the BAF-SPDB unit, the operation temperature should be set above 18 °C. In addition, the influence of the macro operation parameters on the performance of the BAF and SPDB has a direct relationship with the dynamic changes of the micro microbial community. The influence of temperature on nitrification performance in BAF was mainly embodied in the change of composition, amount and activity of ammonia oxidizing bacteria Candidatus Nitrospira defluvii and nitrite oxidizing bacteria Nitrosomonas sp. Nm47, while that on denitrification performance in SPDB is mainly embodied in the change of composition and amount of solid carbon substrate degrading denitrifying bacteria Pseudomonas sp., Myxobacterium AT3-03 and heterotrophic denitrifying bacteria Dechloromonas agitate, Thauera aminoaromatica, Comamonas granuli and Rubrivivax gelatinosus.
Synthesis and Electrochemical and Spectroscopic Characterization of 4,7-diamino-1,10-phenanthrolines and Their Precursors
Authors: Nycz Jacek , Wantulok Jakub , Sokolova Romana , Pajchel Lukasz , Stankevič Marek , Szala Marcin , Malecki Jan Grzegorz , Swoboda Daniel
Published: November 2019

New approaches to the synthesis of 4,7-dichloro-1,10-phenanthrolines and their corresponding 9H-carbazol-9-yl-, 10H-phenothiazin-10-yl- and pyrrolidin-1-yl derivatives were developed. Their properties have been characterized by a combination of several techniques: MS, HRMS, GC-MS, electronic absorption spectroscopy and multinuclear NMR in both solution and solid state including 15N CP/MAS NMR. The structures of 5-fluoro-2,9-dimethyl-4,7-di(pyrrolidin-1-yl)-1,10-phenanthroline (5d), 4,7-di(9H-carbazol-9-yl)-9-oxo-9,10-dihydro-1,10-phenanthroline-5-carbonitrile (6a) and 4,7-di(10H-phenothiazin-10-yl)-1,10-phenanthroline-5-carbonitrile (6b) were determined by single-crystal X-ray diffraction measurements. The nucleophilic substitutions of hydrogen followed by oxidation produced compounds 6a and 6b. The electrochemical properties of selected 1,10-phenanthrolines were investigated using cyclic voltammetry and compared with commercially available reference 1,10-phenanthrolin-5-amine (5l). The spatial distribution of frontier molecular orbitals of the selected compounds has been calculated by density functional theory (DFT). It was shown that potentials of reduction and oxidation were in consistence with the level of HOMO and LUMO energies.
Interfacial Behavior of Oligo(Ethylene Glycol) Dendrons Spread Alone and in Combination with a Phospholipid as Langmuir Monolayers at the Air/Water Interface
Authors: Shi Da , Nguyen Dinh-Vu , Maaloum Mounir , Gallani Jean-Louis , Felder-Flesch Delphine , Krafft Marie Pierre
Published: November 2019

Dendrons consisting of two phosphonate functions and three oligo(ethylene glycol) (OEG) chains grafted on a central phenoxyethylcarbamoylphenoxy group were synthesized and investigated as Langmuir monolayers at the surface of water. The OEG chain in the para position was grafted with a t-Bu end-group, a hydrocarbon chain, or a partially fluorinated chain. These dendrons are models of structurally related OEG dendrons that were found to significantly improve the stability of aqueous dispersions of iron oxide nanoparticles when grafted on their surface. Compression isotherms showed that all OEG dendrons formed liquid-expanded Langmuir monolayers at large molecular areas. Further compression led to a transition ascribed to the solubilization of the OEG chains in the aqueous phase. Brewster angle microscopy (BAM) provided evidence that the dendrons fitted with hydrocarbon chains formed liquid-expanded monolayers throughout compression, whilst those fitted with fluorinated end-groups formed crystalline-like domains, even at large molecular areas. Dimyristoylphosphatidylcholine and dendron molecules were partially miscible in monolayers. The deviations to ideality were larger for the dendrons fitted with a fluorocarbon end-group chain than for those fitted with a hydrocarbon chain. Brewster angle microscopy and atomic force microscopy supported the view that the dendrons were ejected from the phospholipid monolayer during the OEG conformational transition and formed crystalline domains on the surface of the monolayer.
In Situ SABRE Hyperpolarization with Earth’s Field NMR Detection
Authors: Hill-Casey Fraser , Sakho Aminata , Mohammed Ahmed , Rossetto Matheus , Ahwal Fadi , Duckett Simon B. , John Richard O. , Richardson Peter M. , Virgo Robin , Halse Meghan E.
Published: November 2019

Hyperpolarization methods, which increase the sensitivity of nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI), have the potential to expand the range of applications of these powerful analytical techniques and to enable the use of smaller and cheaper devices. The signal amplification by reversible exchange (SABRE) method is of particular interest because it is relatively low-cost, straight-forward to implement, produces high-levels of renewable signal enhancement, and can be interfaced with low-cost and portable NMR detectors. In this work, we demonstrate an in situ approach to SABRE hyperpolarization that can be achieved using a simple, commercially-available Earth’s field NMR detector to provide 1H polarization levels of up to 3.3%. This corresponds to a signal enhancement over the Earth’s magnetic field by a factor of ε > 2 × 108. The key benefit of our approach is that it can be used to directly probe the polarization transfer process at the heart of the SABRE technique. In particular, we demonstrate the use of in situ hyperpolarization to observe the activation of the SABRE catalyst, the build-up of signal in the polarization transfer field (PTF), the dependence of the hyperpolarization level on the strength of the PTF, and the rate of decay of the hyperpolarization in the ultra-low-field regime.
An Effective Cationic Human Serum Albumin-Based Gene-Delivery Carrier Containing the Nuclear Localization Signal
Authors: Guan Guannan , Song Baohui , Zhang Jie , Chen Kang , Hu Haiyang , Wang Mingyue , Chen Dawei
Published: November 2019

Considerable effort has been devoted to the development of gene carriers over the years. However, toxicity, immunogenicity, and low transfection efficiency are still major barriers. How to overcome these obstacles has become a burning question in gene delivery. In the present study, a simple cationic human serum albumin (CHSA)-based gene-delivery system containing nuclear localization signals (NLSs) was constructed to conquer the limitations. CHSA/NLS/plasmid DNA (pDNA) complexes were prepared and characterized by Hoechst 33258 intercalation, gel retardation assay, morphological analysis, circular dichroism (CD) spectroscopy, particle size, and zeta potential measurements. Results showed that CHSA/NLS/pDNA complexes were able to condense and protect pDNA with high encapsulation efficiency. The complexes displayed a nutritional effect on cells at a low concentration and there was no significant cytotoxicity or immunogenicity. In addition, CHSA/NLS/pDNA complexes exhibited excellent cellular uptake rates and the mechanism was mainly the clathrin or macropinocytosis-dependent endocytosis pathway. Furthermore, CHSA/NLS/pDNA significantly enhanced gene expression efficiency in vitro. More importantly, CHSA/NLS/pDNA complexes showed a desired antitumor effect in vivo, exhibiting the highest inhibition rate (57.3%) and significant upregulation in p53 protein. All these results confirm that CHSA/NLS/pDNA complexes have a bright future as a safe and effective delivery system for gene therapy.
GAMBARAN KEJADIAN INFEKSI SALURAN KEMIH PADA IBU HAMIL DI BADAN RUMAH SAKIT UMUM TABANAN
Authors: Widhya Cok Dewi
Published: November 2019

Abstract:Background:Urinary tract infection (UTI) is an inflammatory reaction of urothelium cells that line the urinary tract due to the proliferation of microorganisms. During pregnancy, dilatation occurs on the ureter and there is a decrease in ureteral peristalsis which increases the risk of bacterial growth. Aims:The purpose of this study was to determine the incidence of UTI in pregnant women at BRSU Tabanan. Methods:This study was a descriptive study with population of 160 people and sample of 32 people selected by non-probability sampling technique with accidental sampling method.Examination of respondent's urine sample was done by urine culture with standard loop method. Results:The result of this study indicate 19% of pregnant women had calculated colony 105 CFU/ml which can be indicated as UTI.Conclusion:From the result of the study, it was concluded that the incidence of UTI was most prevalent in pregnant women of the age group 20-35 years, pregnant women in the third trimester of pregnancy, in pregnant women with sexual activity 1x/week, in pregnant women with elementary and high school education, and in pregnant women who change underwear twice or more per day and clean the external urinary tract from the front to the back. Keywords :Urinary Tract Infection (UTI), pregnancy
GAMBARAN KADAR ASAM URAT, GLUKOSA DARAH DAN TINGKAT PENGETAHUAN LANSIA DI DESA SAMSAM KECAMATAN KERAMBITAN KABUPATEN TABANAN
Authors: Arjani Ida
Published: November 2019

Background Uric acid is an adjunct product of normal metabolism of the digestion of protein foods containing purines or from the decomposition of purines (damaged body cells), which should be excreted through the kidneys, feces or sweat. While blood glucose levels should be maintained in sufficient concentration to provide nutrients for the organs of the body. Conversely, too high glucose concentrations can also have negative effects such as osmotic diuresis and cell dehydration.The purpose of this study was to determine the description of uric acid levels, blood glucose and level of knowledge of the elderly in Samsam Village, Kerambitan District, Tabanan Regency.Method, The type of research used is descriptive. The population in this study were all elderly in Samsam village area with sample size of 57 samples. Sampling technique used Nonprobability Sampling and sampling with Accidental Sampling.Result.From 57 respondents, there were 14 men (25%), women 43 people (75%), age group ≤ 60 years were 18 persons (32%) and age group 60 years were 39 people (68% ). The results of examination of uric acid levels of respondents in the normal category of 7 people (12%) and high 50 people (88%). Blood Glucose Levels when the respondents were normal 52 people (91%) and high 5 people (9%). Knowledge of respondents was 22 people (39%) in good category and 35 people (61%) in medium category.Conclusion, as many as 88% of respondents have high uric acid levels, 9% of respondents have high blood glucose levels and 61% of respondents have knowledge in the category of being Keywords: Uric Acid Level, Blood Glucose, Elderly’s knowledge
GAMBARAN RETIKULOSIT TERHADAP PEMBERIAN OBAT ANTI TUBERKULOSIS (OAT) PADA PASIEN TUBERKULOSIS PARU DI PUSKESMAS PERUMNAS KADIA KOTA KENDARI
Authors: Idris Sri Aprilianti
Published: November 2019

Tuberkulosis adalah penyakit infeksi akibat kuman Mycobacterium tuberculosis. Pengobatan tuberkulosis dengan obat anti tuberkulosis (OAT) mempunyai efek toksik diantaranya terhadap efek samping reaksi hematologik seperti anemia, agranulositosis, eosinofilia dan trombositopenia. Hitung retikulosit pada pasien tanpa anemia berkisar antara 1-2%. Jumlah ini penting karena dapat digunakan sebagai indikator produktivitas dan aktivitas eritropoesis di sumsum tulang dan membantu untuk menentukan klasifikasi anemia sebagai hiperproliferatif, normoproliferatif atau hipoproliferatif. Penelitian ini merupakan penelitian deskriptif, sampel penelitian ini adalah pasien tuberkulosis paru yang sedang menjalani pengobatan OAT diambil secara accidental sampling. Hasil penelitian menunjukkan18 sampel jumlah retikulosit pasien yang mengkonsumsi Obat Anti Tuberkulosis (OAT) di Puskesmas Perumnas Kadia Kota Kendari di peroleh nilai retikulosit normal sebanyak 2 orang (11%) dan yang tidak normal sebanyak 16 orang (89%).
KEMAMPUAN DAYA LARVASIDA EKSTRAK DAUN ALPUKAT (Persea americana Mill.) TERHADAP Culex quinquefasciatus
Authors: Setya Adhi
Published: November 2019

Abstract BackgroundCulexquinquefasciatusadalahkelompoknyamuk yang pentingdansalahsatuhama yang seriusdarisudutpandangkesehatanmasyarakat. Pengendalian secara kimiawimerupakanstrategiefektif yang digunakansecaraluassetiapharidikehidupantetapibanyakkonsekuensinegatifdari pemakaiannya. Di antarabiopestisida, tanaman alpukat layak menjadi kandidat penelitian karena kaya akan kandungan fitokimia anti serangga.Method Penelitian ini merupakan uji eksperimental dengan rancangan studi Post-test With Control yang hasilnya diolah menggunakan analisis probit. Konsetrasi dilakukan dengan delapan variasi (0,1%, 0,05%, 0,025%, 0,0125%, 0,006%, 0,003%, 0,001% dan 0,0007%), dengan masing-masing konsentrasi dilakukan tiga kali pengulangan. Sebagai kontrol positif dalam penelitian ini menggunakan temefos. Jumlah larva instar III yang digunakan tiap perlakuan sebanyak 10 ekor. Result Dari hasil fitokimia ekstrak ditemukan alkaloid, flavonoid dan saponin. Analisis probit menunjukan lethal consentration (LC 90) terjadi pada konsentrasi 0,0314% dan kontrol positif berada pada konsentrasi 0,01%. Suhu, kelembaban dan pH menunjukan dalam batas aman untuk larva, yaitu secara berurutan 23oC, 68% dan 6.Conclusion Kemampuan larvasida dari ekstrak daun alpukat berada pada konsentrasi 0,0314%. Hasil ini masih sedikit lebih tinggi dibandingkan kontrol positif (temefos), yaitu 0,01%.Keywords: Culexquinquefasciatus, daun alpukat, ekstrak, larvasida
UJI AKTIVITAS ANTIBAKTERI REBUSAN DAUN SIRIH (Piper betle Linn) TERHADAP BAKTERI Streptococcus pyogenes
Authors: Mastra Nyoman
Published: November 2019

ABSTRACTBackground: Infection is a disease caused by pathogenic microbes and is very dynamic. ISPA is defined as an acute respiratory disease caused by infectious agents that were transmitted from human to human. One of the microbes that caused ISPA is Streptococcus pyogenes, which is a gram-positive bacteria and belongs to Streptococcus sp. β-hemolytic class A. Nowadays, many people are begin to use natural materials to deal with microbial infections. One of them is the betel leaf (Piper betle Linn.) Which has antibacterial and antibiotic components for the treatment of respiratory problems, and bacterial infectious diseases.Purpose: This research was conducted with the aim to know the antibacterial activity of betel leaves (Piper betle Linn) decoction against Streptococcus pyogenes bacteria. Methods: This research used true experimental design with Posttest Only Control Design, and data analysis with One Way Anova and Least Significant Deference (LSD). Betel leaves decoction water is made in concentrations of 20%, 40%, 60%, 80%, and 100%, then tested on Streptococcus pyogenes bacteria with two replicates and four repetitions.Result: From a total of 40 data obtained, the mean diameter of the inhibitory zone at each concentrations is 20% 0 mm, 40% 12.9 mm, 60% 22.7 mm, 80% 25.5 mm, and 100% 30 mm.Conclution: Betel leaves decoction water is able to inhibit the growth of Streptococcus pyogenes with significant difference of drag zone diameter at each concentration.  Keywords: Antibacterial, Betel Leaves, Streptococcus pyogenes
HUBUNGAN DISIPLIN, PENDIDIKAN DAN PELATIHAN DENGAN KINERJA KARYAWAN PDAM TIRTA INDRA RENGAT KABUPATEN INDRAGIRI HULU
Authors: Putri Meilya Karya , Maralis Reni
Published: November 2019

Penelitian ini bertujuan untuk mengetahui hubungan disiplin, pendidikan dan pelatihan dengan kinerja karyawan PDAM Tirta Indra Rengat Kabupaten Indragiri Hulu. Jenis Penelitian ini adalah Penelitian Kuantitatif. Penelitian ini menggunakan data primer  melalui kuesioner. Jumlah responden dalam  penelitian ini berjumlah 53 karyawan. Teknik Pengambilan Sampel yaitu Proportionate Stratified Random Sampling. Analisis data yang digunakan dalam penelitian ini adalah Uji Instrumen, Uji Asumsi Klasik, Analisis Regresi Linier Berganda, dan Uji Hipotesis.  dengan bantuan SPSS versi 21. Hasil Penelitian menunjukkan adanya hubungan disiplin dengan kinerja yang signifikan  dan bersifat positif serta berada pada kategori Sedang. Hubungan yang kuat, positif dan signifikan antara pendidikan dan pelatihan dengan kinerja. Disiplin, Pendidikan dan Pelatihan  berpengaruh secara bersama-sama terhadap kinerja karyawan.
Tensiones en torno al reconocimiento indígena: la lucha por ser mapuche y tehuelche en la costa y valle de Chubut
Authors: Stella Valentina
Published: November 2019

En el año 2009 comencé a trabajar junto con comunidades mapuche-tehuelche de la costa y valle de la provincia de Chubut. Durante aquellos años, muchas de las luchas y demandas giraron en torno a los sentidos locales de pertenencia y a la particularidad política que adquiere la doble adscripción como mapuche-tehuelche en esta región. La conformación de comunidades que se auto-adscriben pertenecientes a estos dos pueblos es una de las características que definió el movimiento indígena en la provincia, y particularmente en la costa y valle. El presente trabajo, por lo tanto, se centra en historizar aquel proceso de fortalecimiento y visibilidad de sus identidades para comprender las formas en que las personas mapuche-tehuelche fueron cambiando las condiciones que determinaban sus modos de aparecer en los espacios públicos y las formas en que fueron tomando conciencia de la responsabilidad política de ser los agentes de su propia historia.
White Innocence: Paradoxes of colonialism and race
Authors: Gaona Melina
Published: November 2019

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Cartilagem articular, patogênese e tratamento da osteoartrite
Authors: Ocampo Pablo Eduardo , Vallejo Viviana Helena , Canavese Rahal Sheila
Published: November 2019

A osteoartrite caracteriza-se por dor e claudicação, sendo considerada processo não específico, mais sim uma sequela comum a várias formas de lesão articular, com envolvimento de fatores biológicos e mecânicos. Desta forma, o objetivo da presente revisão foi discorrer sobre alguns aspectos da cartilagem articular (generalidades, histogênese), patogênese da osteoartrite, bem como algumas possibilidades de tratamentos intra-articulares para a osteoatrite. A cartilagem articular, juntamente com o líquido sinovial, têm papel mecânico importante nas articulações diartrodiais. Os condrócitos estão entre os principais componentes da cartilagem articular e são apontados como células altamente diferenciadas com capacidade limitada de proliferação e migração. O outro componente é a matriz extracelular constituída de colágeno tipo II, proteoglicanos, proteínas não colagenosas, glicoproteínas, água e eletrólitos. A osteoartrite é classificada como doença articular não inflamatória, com múltiplas interações bioquímicas e biomecânicas. Todos os componentes da articulação podem ser comprometidos, porém a cartilagem é considerada o tecido alvo. A afecção pode ser classificada como primária, que ocorre predominantemente em animais idosos, e secundária, decorrente de doenças que afetam a articulação e as estruturas de suporte. Entre os tratamentos intra-articulares para a osteoartrite estão a viscossuplementação com ácido hialurônico, o uso de corticosteroides, e a combinação de ácido hialurônico e corticosteroides. Contudo, há ainda várias controvérsias quanto à eficácia.
THE RELATONSHIP BETWEEN THE INTAKE OF ENERGY,PROTEIN, VITAMIN A AND ZINC (Zn) AND STUNTING IN THE AGE OF EARLY PERIOD IN ENTERING SCHOOL IN CANDIREJO VILLAGE
Authors: Kumaladewi Desy , Maryanto Sugeng , Septiar Pontang Galeh
Published: November 2019

Stunting is one of the effects of lack of nutrients that lasts a long time. Stunting can occur due to deficiency of macronutrients and macronutrients that play a role in the growth, such as energy, protein, vitamin A and zinc (Zn). The aim of this study was determine the relationship between the intake of energy, protein, vitamin A and zinc (Zn) and the incidences of stunting in children of school age in Candirejo Village This research was The study correlation with cross sectional approach. The population in this study were all first year students in Candirejo village. It obtained 56 children with total sampling method. Method of data taking used microtoise, digital scale and FFQ. Bivariate analysis used Pearson product moment and alternative test of Spearman rho (α=0,05) The average energy intake in children was 86.5% RDA. The average protein intake in children was 106.3% RDA. The average intake of vitamin A in children was 111.9% RDA. The average intake of zinc in children was 64.4% RDA. From 56 childs 37,5% was stunting and 62,5% no stunting. There was no relationship between the intake of energy, protein and vitamin A with the incidences of stunting (p = 0.129, p = 0.139, p = 0.200), and there was a correlation between zinc intake with the incidences of stunting (p = 0.014) There was no relationship between the intake of energy, protein and vitamin A with the incidences of stunting in children of school-age in Candirejo village. There was a relationship between zinc intake with the incidences of stunting in school-age children in the Candirejo village.
Determination of Soil Properties and Fungal Interrelations Influenced by Forest Restoration on a Contaminated Zinc Mining Area
Authors: Kantong Chutima , Suntornvongsakul Kallaya , Lee Yang-Soo
Published: November 2019

Forest restoration in a contaminated zinc mining area must take into account the environmental soil properties. This study aimed to analyze the soil properties from the three different stages of restored forests, at 3, 7 and 17, focusing on the impact on soil microorganisms and availability of fungal species. Three study sites were selected, all located in a zinc mining area in Mae Sot District, Tak Province, Thailand. The results showed that observed soil properties especially soil texture, moisture and nutrients differed between stand initiation and regrowth forests and affected the distribution of fungal species. Soils in older forest stands up to 17 years old showed higher sand content and reduced soil moisture, SOM, and certain nutrients. Forest restoration was found to favour development of a range of soil properties, some of which were suitable for fruiting in nine fungal species from the following families: Agaricaceae, Psathyrellaceae, Cantharellaceae, Phallacae, Coprinaceae, Sclerodermataceae, Lycoperdaceae, Marasmiaceae, and Clavariaceae.
SCREENING OF PREGNANT WOMEN FOR PRESENCE OF IGG
ANTIBODIES FOR RUBELLA, MUMPS, MEASLES AND VARICELLA VIRUSES
IN TERTIARY CARE HOSPITAL , JAIPUR
Authors: Malav Seema , Malhotr Bharti
Published: November 2019

Background : The aim of this study were assess the susceptible pregnant women for vaccine preventable
infection like rubella, mumps, measles and varicella viruses. Infection of mothers with these viruses
during pregnancy can be serious. They can cause congenital infections, miscarriage, stillbirth and death of fetuses.
Material and Method : This study is cross sectional. To determine the presence of IgG antibodies for rubella, mumps, measles
and varicella viruses, blood samples were collected, stored at -700 c. Serum was separated for detection of IgG antibodies for
these viruses by using enzyme linked immunosorbant assay.
Results : Of 277 samples evaluated for IgG antibodies. Susceptibility Of pregnant women for rubella, mumps measles and
varicella viruses were 7.6%, 17.6%,7.2% and 19.5% respectively. Susceptibility rates for rubella and mumps were higher in rural
population as compares to urban while for varicella urban population was more susceptible, but it was not statistically
signicant. No correlation could be observed in susceptibility to different to different viruses and their education status and age
of patients, but youngest age group was most susceptible to varicella and oldest group to rubella. Primigravida were more
susceptible to rubella and varicella while multigravida were more susceptible to mumps and measles.
Conclusion : Majority of the pregnant women had protective levels of IgG antibody although susceptibility to rubella, mumps
measles and varicella were low. Intensication of MMRV immunization of all females of child-bearing age is advocated.