bluuebunny/crossref_metadata_2025 huggingface dataset:
Longitudinal and Cross-Sectional Evaluation of Two Commercial Swine Breeding Herds to Characterize Neutralizing Antibody Levels following Porcine Epidemic Diarrhea Virus Outbreaks
Authors: Brown Justin , Skoland Kristin , Kittrell Heather , Ellingson Josh , Thomas Paul , Ruston Chelsea , Baum David , Karriker Locke
Published: February 2024

Neutralizing antibodies to Porcine Epidemic Diarrhea Virus (PEDV) can be detected by 3 weeks post-infection and remain detectable through at least 24 weeks post-infection. The objective of this study was to evaluate the levels of neutralizing antibodies in sow and piglet serum and sow milk to determine the duration of neutralizing antibodies following PEDV outbreaks. Two farms were selected for the study following outbreaks of PEDV. Monthly, cohorts of sows were sampled and followed through two farrowings. Following each farrowing, samples from piglets and milk were collected. Samples were evaluated for PEDV-neutralizing antibodies by a high-throughput fluorescent neutralization assay. Although neutralizing antibodies to PEDV can be detected throughout 15 months post-outbreak, a decrease in circulating neutralizing antibody levels is noted in farms beginning at six months post-outbreak. With decreasing levels, farms may become more vulnerable to PEDV outbreaks, and practitioners can focus on this time window to implement intervention strategies.
Differential Impact of Massachusetts, Canadian 4/91, and California (Cal) 1737 Genotypes of Infectious Bronchitis Virus Infection on Lymphoid Organs of Chickens
Authors: Abd-Elsalam Reham M. , Najimudeen Shahnas M. , Mahmoud Motamed E. , Hassan Mohamed S. H. , Gallardo Rodrigo A. , Abdul-Careem Mohamed Faizal
Published: February 2024

Infectious bronchitis virus (IBV) induces severe economic losses in chicken farms due to the emergence of new variants leading to vaccine breaks. The studied IBV strains belong to Massachusetts (Mass), Canadian 4/91, and California (Cal) 1737 genotypes that are prevalent globally. This study was designed to compare the impact of these three IBV genotypes on primary and secondary lymphoid organs. For this purpose, one-week-old specific pathogen-free chickens were inoculated with Mass, Canadian 4/91, or Cal 1737 IBV variants, keeping a mock-infected control. We examined the IBV replication in primary and secondary lymphoid organs. The molecular, histopathological, and immunohistochemical examinations revealed significant differences in lesion scores and viral distribution in these immune organs. In addition, we observed B-cell depletion in the bursa of Fabricius and the spleen with a significant elevation of T cells in these organs. Further studies are required to determine the functional consequences of IBV replication in lymphoid organs.
HPV and Cervical Cancer: Molecular and Immunological Aspects, Epidemiology and Effect of Vaccination in Latin American Women
Authors: Hernández-Silva Christian David , Ramírez de Arellano Adrián , Pereira-Suárez Ana Laura , Ramírez-López Inocencia Guadalupe
Published: February 2024

Cervical cancer is primarily caused by Human Papillomavirus (HPV) infection and remains a significant public health concern, particularly in Latin American regions. This comprehensive narrative review addresses the relationship between Human Papillomavirus (HPV) and cervical cancer, focusing on Latin American women. It explores molecular and immunological aspects of HPV infection, its role in cervical cancer development, and the epidemiology in this region, highlighting the prevalence and diversity of HPV genotypes. The impact of vaccination initiatives on cervical cancer rates in Latin America is critically evaluated. The advent of HPV vaccines has presented a significant tool in combating the burden of this malignancy, with notable successes observed in various countries, the latter due to their impact on immune responses. The review synthesizes current knowledge, emphasizes the importance of continued research and strategies for cervical cancer prevention, and underscores the need for ongoing efforts in this field.
Analysis of Chicken IFITM3 Gene Expression and Its Effect on Avian Reovirus Replication
Authors: Ren Hongyu , Wang Sheng , Xie Zhixun , Wan Lijun , Xie Liji , Luo Sisi , Li Meng , Xie Zhiqin , Fan Qing , Zeng Tingting , Zhang Yanfang , Zhang Minxiu , Huang Jiaoling , Wei You
Published: February 2024

Interferon-inducible transmembrane protein 3 (IFITM3) is an antiviral factor that plays an important role in the host innate immune response against viruses. Previous studies have shown that IFITM3 is upregulated in various tissues and organs after avian reovirus (ARV) infection, which suggests that IFITM3 may be involved in the antiviral response after ARV infection. In this study, the chicken IFITM3 gene was cloned and analyzed bioinformatically. Then, the role of chicken IFITM3 in ARV infection was further explored. The results showed that the molecular weight of the chicken IFITM3 protein was approximately 13 kDa. This protein was found to be localized mainly in the cytoplasm, and its protein structure contained the CD225 domain. The homology analysis and phylogenetic tree analysis showed that the IFITM3 genes of different species exhibited great variation during genetic evolution, and chicken IFITM3 shared the highest homology with that of Anas platyrhynchos and displayed relatively low homology with those of birds such as Anser cygnoides and Serinus canaria. An analysis of the distribution of chicken IFITM3 in tissues and organs revealed that the IFITM3 gene was expressed at its highest level in the intestine and in large quantities in immune organs, such as the bursa of Fabricius, thymus and spleen. Further studies showed that the overexpression of IFITM3 in chicken embryo fibroblasts (DF-1) could inhibit the replication of ARV, whereas the inhibition of IFITM3 expression in DF-1 cells promoted ARV replication. In addition, chicken IFITM3 may exert negative feedback regulatory effects on the expression of TBK1, IFN-γ and IRF1 during ARV infection, and it is speculated that IFITM3 may participate in the innate immune response after ARV infection by negatively regulating the expression of TBK1, IFN-γ and IRF1. The results of this study further enrich the understanding of the role and function of chicken IFITM3 in ARV infection and provide a theoretical basis for an in-depth understanding of the antiviral mechanism of host resistance to ARV infection.
The Arg753Gln Polymorphisms in Toll-like Receptor 2 in a Syphilis-Infected and Control Population in The Netherlands: Can Differences in the Number of Self-Reported Sexual Contacts Indicate Protection against Syphilis?
Authors: Vrbová Eliška , Zondag Helene , Bruisten Sylvia , Šmajs David
Published: February 2024

The Arg753Gln polymorphism in Toll-like receptor 2 has been associated with an increased risk of bacterial infections as well as with protection from the late stages of Lyme disease and the acquisition of syphilis. In this study, we determined the presence of this polymorphism in samples collected from men having sex with men/men with women in the Amsterdam Cohort Studies. The presence of the polymorphism was determined by nested PCR, followed by Sanger sequencing. A set of 90 syphilis-seronegative individuals was compared to 95 syphilis-diagnosed participants. A polymorphism allele frequency of 3.9% was found in the control group and 2.63% in the syphilis case group, respectively. None of the individuals showed a homozygous Arg753Gln polymorphism. The number of self-reported sexual contacts was higher in the group of syphilis patients compared to the control group (p = 0.0063). Moreover, in the syphilis case group (n = 49), participants heterozygous for the TLR2-Arg753Gln reported higher numbers of sexual contacts (p = 0.037) compared to wild-type homozygotes. Our findings suggest a possible protective effect of TLR2-Arg753Gln in the acquisition of syphilis. In addition, the determination of the number of self-reported sexual contacts can be used in an evaluation of the protective effect of polymorphism in a population with a low prevalence of it.
Comparing and Contrasting Near-Field, Object Space, and a Novel Hybrid Interaction Technique for Distant Object Manipulation in VR
Authors: Hsieh Wei-An , Chien Hsin-Yi , Brickler David , Babu Sabarish V. , Chuang Jung-Hong
Published: February 2024

In this contribution, we propose a hybrid interaction technique that integrates near-field and object-space interaction techniques for manipulating objects at a distance in virtual reality (VR). The objective of the hybrid interaction technique was to seamlessly leverage the strengths of both the near-field and object-space manipulation techniques. We employed bimanual near-field metaphor with scaled replica (BMSR) as our near-field interaction technique, which enabled us to perform multilevel degrees-of-freedom (DoF) separation transformations, such as 1~3DoF translation, 1~3DoF uniform and anchored scaling, 1DoF and 3DoF rotation, and 6DoF simultaneous translation and rotation, with enhanced depth perception and fine motor control provided by near-field manipulation techniques. The object-space interaction technique we utilized was the classic Scaled HOMER, which is known to be effective and appropriate for coarse transformations in distant object manipulation. In a repeated measures within-subjects evaluation, we empirically evaluated the three interaction techniques for their accuracy, efficiency, and economy of movement in pick-and-place, docking, and tunneling tasks in VR. Our findings revealed that the near-field BMSR technique outperformed the object space Scaled HOMER technique in terms of accuracy and economy of movement, but the participants performed more slowly overall with BMSR. Additionally, our results revealed that the participants preferred to use the hybrid interaction technique, as it allowed them to switch and transition seamlessly between the constituent BMSR and Scaled HOMER interaction techniques, depending on the level of accuracy, precision and efficiency required.
Kinetics of Decolorization of Reactive Textile Dye via Heterogeneous Photocatalysis Using Titanium Dioxide
Authors: Carrasco-Venegas Luis Américo , Castañeda-Pérez Luz Genara , Martínez-Hilario Daril Giovani , Medina-Collana Juan Taumaturgo , Calderón-Cruz Julio Cesar , Gutiérrez-Cuba César , Cuba-Torre Héctor Ricardo , Núñez Alex Pilco , Herrera-Sánchez Sonia Elizabeth
Published: February 2024

The textile industry is known for its excessive water consumption and environmental impact. One of the major challenges it faces is managing pollution generated by dyes, particularly bifunctional dyes, such as sumireact supra yellow s-hbu, with a red appearance and sumifix supra lemon-yellow e-xf, with a yellow appearance. This study aimed to investigate the decolorization kinetics of synthetic solutions of said bifunctional dyes, which comprise triazine and vinylsulfon. We conducted various tests, including modifications of pH, the addition of TiO2 P-50 nanoparticles, exposure to solar radiation, limited contact with oxygen, and eolic agitation. The initial solutions had a concentration of 1000 ppm of textile dye. The study showed that the reaction order for the “red” solutions in the R6 and R9 reactors and all the yellow solutions was ½. The concentration of nanoparticles and pH had a significant impact on the reaction rate. The yellow solutions with a concentration of 800 ppm and pH levels of 3.15, 4.13, and 2.25 demonstrated 100% color discoloration, followed by solutions with a concentration of 400 ppm and pH levels of 3.15, 2.25, and 4.13. The analysis of variance confirmed the reaction rate constants for the yellow solutions and emphasized the significance of pH in this process.
Surrogate-Based Uncertainty Analysis for Groundwater Contaminant Transport in a Chromium Residue Site Located in Southern China
Authors: Zou Yanhong , Yousaf Muhammad Shahzad , Yang Fuqiang , Deng Hao , He Yong
Published: February 2024

Numerical modeling is widely acknowledged as a highly precise method for understanding the dynamics of contaminant transport in groundwater. However, due to the intricate characteristics of environmental systems and the lack of accurate information, the results are susceptible to a significant degree of uncertainty. Numerical models must explicitly consider related uncertainties in parameters to facilitate robust decision-making. In a Chromium Residue Site located in southern China (the study area), this study employed Monte Carlo simulation to assess the impact of variability in key parameters uncertainty on the simulation outcomes. Variogram analysis of response surface (VARS), global sensitivity analysis, and an XGBoost (version 2.0.0)-based surrogate model was employed to overcome the substantial computational cost of Monte Carlo simulation. The results of numerical simulation indicate that the contaminant is spreading downstream towards the northern boundary of contaminated site near Lianshui River, threatening water quality. Furthermore, migration patterns are complex due to both downstream convection and upstream diffusion. Sensitivity analysis identified hydraulic conductivity, recharge rate, and porosity as the most influential model parameters, selected as key parameters. Moreover, uncertainty analysis indicated that the variability in key parameters has a minimal impact on the simulation outcomes at monitoring wells near the contaminant source. In contrast, at wells positioned a considerable distance from the contaminant source, the variability in key parameters significantly influences the simulation outcomes. The surrogate model markedly mitigated computational workload and calculation time, while demonstrating superior precision and effectively capture the non-linear correlations between input and output of the simulation model.
Charting the 21st Century Rise of For-Profit Residential Child Care
Authors: Sen Robin , Ulybina Olga Alexandrovna , Holmes Lisa
Published: February 2024

This article explores the increasing prevalence of for-profit residential care, with a particular focus on Great Britain, while also drawing on the international evidence from the Global North. Comprising a critical review of the published evidence (both academic and grey literature), the article seeks to examine what might explain the rising prevalence of and the possible associated impacts of the increase in for-profit provision. The findings indicate that the rise of for profit-companies among residential child care providers appears to have occurred by default, rather than explicit policy design. Our analysis also highlights gaps in the knowledge base about the quality of care and whether better quality is associated with the type of provider. Furthermore, the relationships between provider, quality, cost and outcomes are unclear. There are inconsistencies in the evidence base, with different conclusions being reached. However, available evidence tends to suggest the increased prevalence of for-profit residential child care providers has had an overall negative, rather than positive, effect. The best case in favour of the continued use of for-profit residential care is currently a non-moral pragmatic one: that in countries with medium and high prevalence of the use of residential child care, it would be hard to sustain care systems if for-profit providers were to suddenly withdraw or be withdrawn.
Clinical trials through the eyes of Muscovites
Authors:   FSAEI HE I. M. Sechenov First Moscow State Medical University of the Ministry of Health of Russia (Sechenov University), Vyatkina N. Yu. , Krasnova A. D. ,   FSAEI HE I. M. Sechenov First Moscow State Medical University of the Ministry of Health of Russia (Sechenov University), Borisova P. M. ,   FSAEI HE I. M. Sechenov First Moscow State Medical University of the Ministry of Health of Russia (Sechenov University)
Published: February 2024

Clinical trials is an actively developing field of medicine, and Moscow where the key bases for the development, conduct, and registration of the results of trials are located can rightfully be called its center. Residents of the capital constitute the main cohort of the population recruited as volunteers for clinical trials conducted in this region. However, existing fears and myths surrounding the field of clinical trials act as a barrier to attracting new participants. The article presents the results of a medical and sociological study (questionnaire survey) of Moscow residents on their perception of the field of clinical trials, as well as factors of attractiveness and existing fears (anxieties) regarding participation in them. The image of clinical trials in the eyes of Muscovites plays an important role in conducting research, attracting the required number of participants, and forming a trusting attitude of the population towards this field of medicine.
Volunteers in bioequivalence clinical trials: premises for participation. Part 1
Authors:   FSAEI HE I.M. Sechenov First Moscow State Medical University of the Ministry of Health of Russia (Sechenov University), Moscow, Vyatkina N.Yu. , Krasnova A.D. ,   FSAEI HE I.M. Sechenov First Moscow State Medical University of the Ministry of Health of Russia (Sechenov University), Moscow, Borisova P.M. ,   FSAEI HE I.M. Sechenov First Moscow State Medical University of the Ministry of Health of Russia (Sechenov University), Moscow
Published: February 2024

Clinical trials, as an integral stage of the creation of any drug, require volunteers who are ready to go through the testing stage. Clearly, participation in a trial of any drug carries certain health risks, which makes it difficult to recruit volunteers. Development companies use various methods to stimulate potential participants, including regular monitoring of health status, creation of comfortable living conditions, free treatment, financial compensation for risks, etc. Particularly relevant for manufacturing companies is the recruitment of volunteers in case of conducting a bioequivalence phase study, when an already known drug, planned for release under a different brand (name), is being tested. The article presents the results of interviews with volunteers in order to study their motivation to participate in clinical trials of the bioequivalence phase, their experience of such participation, as well as opinions regarding the organization of clinical trials in the Russian Federation. The results of the study demonstrate a high level of interest among the volunteers to regularly participate in bioequivalence studies due to their relative safety for health, as well as financial interest and comfortable organization of the trial process. The socio-demographic profile of the “bioequivalence phase volunteer” is described, and the tendency towards the formation of a community of volunteers with experience of repeated participation in clinical trials for financial reward is identified.
Possibilities of using amiodarone in thyroid pathology
Authors:   FSBEI HE Rostov State Medical University of the Ministry of Health of the Russian Federation, Rostov-on-Don, Russia, Shavkuta G. V. , Shnyukova T. V. ,   FSBEI HE Rostov State Medical University of the Ministry of Health of the Russian Federation, Rostov-on-Don, Russia; OOO Medical Center EUROEXPERT CLINIC, Rostov-on-Don, Russia, Yakovleva N. V. ,   FSBEI HE Rostov State Medical University of the Ministry of Health of the Russian Federation, Rostov-on-Don, Russia, Pakhomova V. M. ,   FSBEI HE Rostov State Medical University of the Ministry of Health of the Russian Federation, Rostov-on-Don, Russia, Shnyukov V. V. ,   OOO Stavmedklinika, Stavropol, Russia, Cherkashin A. A. ,   OOO Medical Center EUROEXPERT CLINIC, Rostov-on-Don, Russia
Published: February 2024

Amiodarone is currently the most effective drug for life-threatening arrhythmias, however, the instructions for its use indicate thyroid dysfunction (hypothyroidism, hyper thyroidism) as contraindications. Due to the high iodine content, amiodarone can cause damage to the thyroid gland (with the development of hypothyroidism or thyrotoxicosis) in 15–20 % of patients. Before starting amiodarone therapy, it is necessary to assess the pa tient's thyroid status with mandatory determination of thyroid-stimulating hormone. In cases where amiodarone is prescribed for primary or secondary prevention of fatal ventricular arrhythmias or when discontinuation of the drug is impossible for other reasons (any form of arrhythmias that occurs with severe clinical symptoms that cannot be eliminated by other means of antiarrhythmic therapy), compensation for impaired thyroid function is carried out while continuing amiodarone intake.
Prevention of arthritis and arthrosis in children.Why are osteobiotics needed after antibiotics?
Authors:   Penza Institute for Advanced Medical Studies, Penza, Russian Federation, Sergeeva-Kondrachenko M. Yu. , Musatova L. A. ,   Medical Institute, Penza State University, Penza, Russian Federation, Alekseeva N. Yu. ,   Penza Institute for Advanced Medical Studies, Penza, Russian Federation, Radchenko L. G. ,   Penza Institute for Advanced Medical Studies, Penza, Russian Federation, Elistratov D. G. ,   Medical Center «Healthy Children», Penza, Russian Federation, Poluboyarinov P. A. ,   Medical Institute, Penza State University, Penza, Russian Federation, Gorina O. S. ,   Penza Regional Clinical Hospital named after N. N. Burdenko, Penza, Russian Federation, Pronkina A. A. ,   Medical Institute, Penza State University, Penza, Russian Federation, Burmistrova S. S. ,   Ryazan State Medical University named after academician I. P. Pavlov, Ryazan, Russian Federation
Published: February 2024

Among the numerous side effects of antibiotic therapy, disorders in the work of the osteoarticular system occupy a separate and insufficiently studied niche. The article examines the effect of antibiotics on bone and cartilage tissue in children. A method for the prevention and therapy of drug-induced osteoarticular pathologies by means of a new group of drugs, osteobiotics, is proposed.
Clinical, genetic and microbiological aspects in patients with atopic dermatitis and ichthyosis
Authors:   Republican Specialized Scientific and Practical Medical Center of Dermatovenereology and Cosmetology of the Ministry of Health of the Republic of Uzbekistan, Mavlyanova Sh. Z. , Eshniyazov M. M. ,   Republican Specialized Scientific and Practical Medical Center of Dermatovenereology and Cosmetology of the Ministry of Health of the Republic of Uzbekistan, Ismogilov A. I. ,   Republican Specialized Scientific and Practical Medical Center of Dermatovenereology and Cosmetology of the Ministry of Health of the Republic of Uzbekistan
Published: February 2024

The article presents a comparative assessment of microbiological, clinical, and genetic aspects in patients with atopic dermatitis and ichthyosis. The results of a study in 62 patients with atopic dermatitis and 19 patients with ichthyosis showed that there was a phenomenon of persistence of opportunistic microorganisms Staphylococcus spp. in skin lesion foci. Thus, in the group of the patients with ichthyosis, the development of persistent forms of bacterial infection caused by MRCoNS is noted in 69.2 % of cases, and in the patients with atopic dermatitis, an invasive form of MRSA-associated bacterial sensitization is found in 49.2 % of cases.
Historical approach to the study of “falsification” and “veiling” procedures in current accounting and financial reporting
Authors:   Federal State Educational Budgetary Institution of Higher Education “Financial University under the Government of the Russian Federation”, Moscow, Russia, Kevorkova Zh. A.
Published: February 2024

Research conducted by Russian and foreign scientists has proven that distortion of financial statements harms not only a wider range of external, but also internal users of financial statements, including employees and management of an economic entity. At the same time, internal users of financial statements suffer both financial and non-financial losses, for example, loss of reputation. In economic theory and accounting practice, falsification and concealment are distinguished as methods of distorting financial statements. Distortion of financial statements as a phenomenon has now taken on a more complex form and has changed in content. It has been determined that the manifestations of distortions in financial statements are largely determined by the features of the process of preparing financial statements, that is, the mechanism of distortion itself, therefore, in order to form the most complete theoretical description of falsification and concealment, it is necessary to analyze the errors identified during inspections of economic entities, to classify them in order to develop methods identifying non-standard business situations, taking into account the historical approach to the study of “falsification” and “veiling” procedures.
Specifics of the calculation by medical organizations of benefits for temporary disability to persons under civil law contracts
Authors:   Department of Economics and Management of the Institute of Economics, Management and Law Moscow City University. Moscow, Shinkareva O. V. , Soloduha P. V. ,   Department of Economics and Management of the Institute of Economics, Management and Law Moscow City University. Moscow
Published: February 2024

The article is devoted to the peculiarities of the calculation by organizations of temporary disability to persons employed under civil law contracts. It was noted that the state, introducing from January 1, 2023, payment of benefits not only to persons working under labor contracts,but also under civil law contracts and author’s order agreements, thereby strengthens social support for such citizens, provided that their earnings for the previous year were at least the federal minimum wage under the employment contract. Thus, the rights of employees under civil law contracts contract in terms of social insurance in case of temporary disability have become equal to the rights of persons working under the employment contract since 2023, and the amount of sick leave is determined in the same way. The article considers the requirements for the earnings of persons working under civil law contracts for receiving temporary disability benefits. The stages of calculating the size of this allowance by the insured are disclosed, as well as practical examples are given. Conclusions based on the results of the study.
Design of Network Management of International Relations, Including the Economic Sphere (рart 2)
Authors:   Financial University under the Government of the Russian Federation, Moscow, Perskaya V. V. , Tolmachev P. I. ,   Financial University under the Government of the Russian Federation, Moscow; Diplomatic Academy of the Ministry of Foreign Affairs of the Russian Federation, Moscow
Published: February 2024

In the second part, the authors explore the ideas of the actual network organization of the world community and emphasize that network regulation of international relations was supposed to be considered in the context of equal participation in the network of all potential actors: from the state to NGOs and NGOs, including TNCs/MNEs and TNBs, as well as various between-people’s (UN, OECD, IMF or WB, etc.) and public organizations (various unions and religious, political communities, including extremely radical ones). In modern conditions, the network management of international organizations and international economic relations is most revealing at the EU level, where the ongoing foreign and foreign economic policy is not connected either with the national interests of the EU countries or with the ability to provide for the vital needs of citizens of the EU countries. The authors focused their attention, while exploring the networkization of international economic relations, on the development of the process of gradual transition by management of the creation of global GDP based on augmentation and its transfer to the competence of artifi cial intelligence (AI). As a counterversion of the networking of international relations and international economic relations, the authors consider the position of countries that defend the promotion of a multipolar confi guration of the world community, since polycentrism presupposes the development and strengthening of the Westphalian system, but taking into account modern trends in the development of the world community. Multipolarity de facto denies the proposed concept of networkization of the Moscow Region.
Digitalization of Trade in Russia by Means of Using Marketplaces
Authors:   Bashkir State University, Institute of Law, Ufa, Nikitina A. A. , Taipova S. A. ,   Bashkir State University, Institute of Law, Ufa
Published: February 2024

Digitalization of trade through marketplaces is actively being introduced into the daily lives of citizens of many countries, this process began to develop especially actively during the quarantine measures during the pandemic in 2020–2021. E-commerce is most active in Asian countries. For example, China has switched to commodity marketplace platforms by 90 percent. To a certain extent, this made it possible to avoid the collapse of the food and commodity markets in 2020–2021. Having proved very popular among the population, this method of sales has fi rmly established itself in the commodity market. In this article, the authors examined what marketplaces are and what types of marketplaces exist in the global space. They also proposed the author’s classification of marketplaces. In addition, the authors presented practical examples of successful cases of Russian marketplaces in the context of the dynamics of economic development and digitalization of trade, as well as current trends and challenges in the fi eld of e-commerce; opportunities and risks of further development of domestic marketplaces and their role in international export activities. At the end of the study, the authors examined the options for using artificial intelligence in electronic commerce.
The effect of dairy farm size on the economic structure and feed consumption: A case study of the Aegean Region
Authors: Güler Duran , Saner Gamze
Published: February 2024

Dairy farming has an important role in agriculture and livestock sector in Türkiye. Cow's milk production constitutes 92.11% of the total milk production in Türkiye. The purpose of this study is to demonstrate the effect of scale size on the economic structure and feed consumption in dairy farms. The research data were obtained from face-to-face surveys conducted with 147 farmers in the Aegean Region. In the study, the farms were divided into four groups based on the number of cows: 5-15 cows, 16-25 cows, 26-40 cows, and 41 cows and above. The total variable cost per livestock unit in the 4th group farms was 26.07% less than the farms in the 1st group. The total production cost per livestock unit in the largest farm group is 25.81% less than that of the smallest farm group. The research findings indicate that large-scale farms take advantage of economies of scale, resulting in lower cost per livestock unit. Additionally, it was observed that as farm size increases, the feed conversion ratio also increases. As farms grow larger, they often have access to economies of scale, better management practices, and improved infrastructure.
La liste des archontes athéniens (IG I3, 1031). Réflexions sur la datation d’une inscription
Authors: Pébarthe Christophe
Published: February 2024

Le fragment c de la liste des archontes (IG I3, 1031) donne l’occasion d’une réflexion sur la datation d’une inscription. Les critères internes sont d’abord étudiés et permettent de définir un intervalle, 450-403. Il apparaît ensuite, qu’au cours de cette période, la dernière décennie du Ve s. fournit un contexte pour la mise sur pierre de cette liste. La date de 410 est proposée, peu après la restauration de la démocratie et le début de la révision des lois.
Isidor Poliak et les deux traductions arabes différentes du De Interpretatione d’Aristote
Authors: Monteil Jean-François
Published: February 2024

Dans le chapitre VII du De Interpretatione, Aristote mutile un système naturel de trois couples de contradictoires naturelles. Il évince le couple où deux universelles naturelles Les hommes sont blancs, Les hommes ne sont pas blancs s’opposent contradictoirement. Conséquence grave : les deux couples de contradictoires naturelles, qu ’Aristote considère exclusivement, sont identifiés illégitimement aux deux couples de contradictoires logiques constituant le carré logique. La mutilation aristotélicienne est dissimulée par la traduction des propositions dites indéterminées. Pour traduire celles-ci, qui, sémantiquement, sont des particulières, les érudits, à l’exception de P. Gohlke, emploient les deux universelles naturelles évincées par le maître ! L’ouvrage d’I. Pollak, publié à Leipzig en 1913, révèle l’origine de cette faute de traduction quasi universelle : la version arabe sur laquelle, malheureusement, Alfarabi fonde son commentaire.
El «eterno retomo al seno preclasal» como referente primario en el complejo ideológico romano medio-republicano
Authors: Domínguez Pérez Juan Carlos
Published: February 2024

We present here evidence for the study of the ideological re-elaboration of the Mid-republican society during the main changes that took place at that period. All items of evidence make up a new state model based on imperialism and conservatism considered as theoretical Republican references.
Horrea d’Andriakè et Patara : un nouveau type d’édifice fonctionnel en Lycie à l’époque impériale
Authors: Cavalier Laurence
Published: February 2024

En se fondant sur des observations menées sur l’aménagement et la localisation des horrea de Lycie, l’auteur pose la question de la fonction de ces grands édifices : s’agit-il d’entrepôts réservés exclusivement au stockage du blé destiné au ravitaillement de Rome ou peut-on les considérer comme une composante d’un système d’échanges commerciaux régionaux et internationaux concernant toutes sortes de denrées ?
Lettres grecques dialectales nord-pontiques (sauf IGDOP 23-26)
Authors: Dana Madalina
Published: February 2024

This paper relates to the lead letters and ostraka discovered in the Black Sea area. According to our evidence, we have observed that almost of all these objects are situated on both peripheries of the Greek world, namely in the hinterland of Massalia and in the Euxine Pontus. Most of them have Ionian dialectal features, as well as a typical onomastics for this Milesian milieu. All these items concern commercial matter and illustrate a high degree of literacy in the Pontic cities.
La déclaration d’hostis de 88 et les douze hostes
Authors: Allély Annie
Published: February 2024

Cette étude a pour but de présenter et d’analyser une procédure utilisée pour la première fois en 88 par Sylla : la déclaration à Eostis. Cette mesure, dans le cadre des guerres civiles de la fin de la République romaine, consiste à assimiler les adversaires politiques à des ennemis extérieurs, c’est-à-dire à des hostes. Pour la déclaration de 88, on recherchera les précédents qui ont pu inspirer Sylla et les raisons qui l’ont conduit à mettre en œuvre cette procédure. On étudiera sa mise en place et toutes les conséquences pour les intéressés.
«Et maintenant, Erato» : à propos d’Enéide VII 37
Authors: Nelis Damien P.
Published: February 2024

Au 37e vers du premier livre de V Enéide, les premiers mots de Junon, men (e) incepto rappellent le premier mot de Y Iliade d’Homère, menin. La deuxième partie de l'Enéide, souvent nommée «l'Iliade » de Virgile, commence au 37e vers du septième livre. Ce parallèle structurel n’est pas fortuit.
Les noms latins de la surface géométrique
Authors: Ferré Barbara
Published: February 2024

As early as the 4th century B.C the Greeks were all agreed to designate geometrical surface by επιφ ανειανwhich refers to all that is visible. Their latin succesors only kept to plane surface which led to some vagueness for several centuries. Towards the end of Antiquity, vocabulary became more fixed and superficies which is the exact copy of επιφ ανειαtakes over. The authors of the period radically break away from their predecessors in order to chose a term which is as close as possible to Greek. This shows the importance of their work in scientific terminology.
Typologie et évolution des installations commerciales dans les villes grecques du IV siècle av. J.-C. et de l’époque hellénistique
Authors: Karvonis Pavlos
Published: February 2024

The first part of the article presents a typology of commercial planning in Greek cities from 4th to 1st century BC. We have drawn a distinction between permanent and temporary installations as well as their identification criteria. In the second part we will examine the commercial organization of cities that had developed significant commercial activities compared with cities with lesser developed commercial activities. This will lead us to an in-depth consideration of the evolution of commercial installations over the period in question.
Parler et penser grec : les Scythes Anacharsis et Toxaris et l’expérience rhétorique de Lucien
Authors: Visa Valérie
Published: February 2024

Three of Lucian’s works (The Scythe, Toxaris and Anacharsis) stage Scythes in the middle of meetings, discussions and debates with Greeks on a one to one basis that follow closely the various phases undergone by the author while becoming familiar with Greek culture himself. This includes a foreigner’s apprenticeship of the language, his assimilation of the culture and also surprise and admiration on discovering other systems of thought and questioning.
Le passage de la République à l’Empire : questions anciennes, nouvelles réponses
Authors: Hurlet Frédéric
Published: February 2024

Cette note de lecture est conçue comme un compte rendu approfondi du recueil rassemblant les nombreuses études consacrées par Klaus Martin Girardet au processus qui a conduit à la disparition de la République romaine et à l’avènement du principat augustéen. Sont présentés de façon détaillée et critique les principaux résultats que la démarche juridique suivie par le savant allemand a permis d’obtenir. On y trouvera à ce titre un état de la question concernant la nature et la définition des pouvoirs détenus par les principaux Imperatores de la fin de la République et du début de l’Empire (Pompée, César, Brutus et Cassius, Antoine, Octavien/ Auguste, Germanicus et Tibère).
The date and context of the Kymaian decrees for Archippe (SEG 33, 1035 - 1041)
Authors: Van Bremen Riet
Published: February 2024

A case is made here for dating the euergetic activities of the Kymaian benefactress Archippè to the 160s or 150s BC rather than to the period after the war against Aristonikos, and for seeing her as closely affiliated with the type of benefactor-philos represented by e.g. Pamphilos of Adramyttion, Asklepides of Pergamon or Herakleides, Timokrates and Eirenias of Miletos (as well as the young Moschion of Priene). It is proposed that the bouleuterion which Archippè built in Kyme should be related, both stylistically and in date, to that built at Miletos between 175 and 164 BC by Herakleides and Timokrates « in the name of king Antiochos IV ». It is speculated that Archippè herself may have had connections to the Seleukid court.
Les effigies monétaires romaines et l’apparition du portrait de César : problèmes légaux et politiques
Authors: Suspène Arnaud
Published: February 2024

Cet article étudie les précédents romains et étrangers qui ont permis l’apparition du portrait monétaire de César en 44 avant notre ère sur décision du Sénat. Ce portrait doit être compris comme une marque d’honneur proportionnée à la nouvelle position de César et non comme un attribut royal ou sacralisant. Mais il procède aussi d’une tentative commune du Sénat et du dictateur pour définir les prérogatives sénatoriales en matière monétaire et poser les bases d’une collaboration générale. La décision des Sénateurs en faveur de César, dont il est montré qu’il s’agit d’une mesure normative d’un genre nouveau, n’est donc pas un trait d 'adulatio mais un aspect particulier d’une réorganisation politique et institutionnelle qui fut interrompue par la mort de César.
Beroso y Giovanni Nanni (Annius Viterbensis) : modelos para el relato de los tiempos míticos en la historiografía española
Authors: Caballero José Antonio
Published: February 2024

Bérose de Babylone a composé au début du IIIe siècle av. J.-C. une œuvre avec laquelle il voulait démontrer aux monarques grecs, qui régissaient alors son pays, l’antiquité de Γ histoire de sa patrie. Bérose ne savait pas que son œuvre aurait le succès qu’elle a eu, d’abord chez les historiens juifs et chrétiens de l’Antiquité tardive et du Moyen-Age et plus tard, dans l’œuvre du dominicain Giovanni Nanni de Viterbe en pleine Renaissance. Dans le présent travail, nous présentons l’analogie entre les deux personnages et étudions l’influence des histoires d’Annius de Viterbe, «le faux Beroso », dans l’historiographie espagnole, tant dans les contenus que dans les méthodes.
Images et société en Lycie au VIe siècle avant J.-C. : le pilier d’Isinda et son programme iconographique
Authors: Colas-Rannou Fabienne
Published: February 2024

Le décor sculpté du pilier funéraire d’Isinda compte parmi les premières images produites en Lycie connues à ce jour. Les choix iconographiques et stylistiques sont l’expression des valeurs, des ambitions sociales et politiques du commanditaire. Ce dernier, potentat ou « dynaste » de culture anatolienne, s’ouvre à dessein à la culture grecque. Le pilier d’Isinda, à l’instar des autres piliers de Lycie méridionale centrale dotés d’un véritable programme iconographique, naît d’une émulation au sein des élites lyciennes, et d’une volonté d’affirmation dans un nouveau cadre politique, celui de l’empire perse, dans le dernier quart du VIe siècle av. J.-C.
Sila no vino a aprender Historia Antigua : El asedio de Atenas en 87/6 a.C.
Authors: Antela-Bernárdez Borja
Published: February 2024

Un des principaux épisodes de la première guerre mithridatique a eu lieu dans la cité d’Athènes. La rupture d’Athènes avec Rome et son alliance avec les Pontes pendant le conflit est pleine de questions sans réponses telles que les changements opérés dans la politique d’Athènes, la manière dont Sulla assiégea la cité en plus de la destruction plus tardive d’Athènes par les troupes romaines. Beaucoup de ces questions, cependant ont trouvé des réponses parmi des arguments qui peuvent être maintenant envisagés sous des angles nouveaux.
Isolamento e identificação de agentes bacterianos causadores de doença periodontal em cães
Authors: Ribeiro Heigly Eduarda Silva , Macente Beatrice Ingrid , Da Cunha Juliana Egas Rodrigues , Bressan Beatriz Navas dos Santos , Mansano Cleber Fernando Menegasso , Frias Danila Fernanda Rodrigues
Published: February 2024

A doença periodontal acomete grande parcela dos cães acima dos quatro anos de idade, sendo caracterizada por placas bacterianas que se formam na superfície dos dentes, calcificando progressivamente até a formação do cálculo dentário. Objetivou-se com o presente trabalho isolar e identificar os agentes microbianos associados aos casos de doença periodontal em cães. Foram selecionados 20 cães com o diagnóstico de doença periodontal graus E2 a E4. Destes foram colhidas amostras na mucosa gengival por meio da fricção de um swab no biofilme dental do canino superior. As amostras foram inoculadas nos meios de cultura TSA (Trypticase Soy Agar) suplementado com extrato de levedura (5mg/ml) e acrescido de sangue equino desfibrinado (5%) (TSAS); TSBV (Trypticase Soy Serum Bacitracin/Vancimicin), BBE (Ágar Bacteroides Bile Esculina); Ágar MacConkey e Ágar EMB (Eosin Methylene Blue Agar). Após o período de incubação, foram obtidas as culturas puras e pelas suas características bioquímico-fisiológicas convencionais. Os dados obtidos foram tabulados e submetidos à análise da variância e a comparação das médias pelo teste de Duncan (p≤5).  Dentre os 137 agentes identificados nos cultivos, observou-se 48,2% para Gram-positivos e 51% Gram-negativos, com prevalências das bactérias dos filos Proteobacteria e Firmicutes. Dentre estes, o gênero/espécie com as mais altas frequências foram bactérias Gram-positivas Staphylococcus spp, com 16 (80%) de frequência e por 15 (75%) de Streptococcus α-hemolitico, seguidas pelas bactérias Gram-negativas, que apresentaram altas frequências com as bactérias E. coli (12 – 60%) e Pasteurella spp (11 – 55%). Com base nos achados, espera-se auxiliar na instituição correta do tratamento, assim como estabelecer medidas profiláticas, para a doença periodontal em cães.
Learning Playing Piano with Bionic-Constrained Diffusion Policy for Anthropomorphic Hand
Authors: Yang Yiming , Wang Zechang , Xing Dengpeng , Wang Peng
Published: February 2024

Anthropomorphic hand manipulation is a quintessential example of embodied intelligence in robotics, presenting a notable challenge due to its high degrees of freedom and complex inter-joint coupling. Though recent advancements in reinforcement learning (RL) have led to substantial progress in this field, existing methods often overlook the detailed structural properties of anthropomorphic hands. To address this, we propose a novel deep RL approach, Bionic-Constrained Diffusion Policy (Bio-CDP), which integrates knowledge of human hand control with a powerful diffusion policy representation. Our bionic constraint modifies the action space of anthropomorphic hand control, while the diffusion policy enhances the expressibility of the policy in high-dimensional continuous control tasks. Bio-CDP has been evaluated in the simulation environment, where it has shown superior performance and data efficiency compared to state-of-the-art RL approaches. Furthermore, our method is resilient to task complexity and robust in performance, making it a promising tool for advanced control in robotics.
Limitations and Strategies toward High-Performance Red Phosphorus Materials for Li/Na-Ion Batteries
Authors: Bai Jin , Li Zhaolin , Wang Xinran , Świerczek Konrad , Wu Chuan , Zhao Hailei
Published: February 2024

Phosphorus, particularly the red phosphorus (RP) allotrope, has been extensively studied as an anode material in both lithium-ion batteries (LIBs) and emerging sodium-ion batteries (SIBs). RP is featured with high theoretical capacity (2,596 mA h g
−1
), suitable low redox potential (~0.7/0.4 V for LIBs/SIBs), abundant resources, and environmental friendliness. Despite its promises, the inherent poor electrical conductivity of RP (~10
−14
S cm
−1
) and significant volume changes during charge/discharge processes (>300%) compromise its cycling stability. In order to address these issues, various countermeasures have been proposed, focusing on the incorporation of materials that provide high conductivity and mechanical strength in composite-type anodes. In addition, the interfacial instability, oxidation, and safety concerns and the low mass ratio of active material in the electrode need to be addressed. Herein, this review summarizes the up-to-date development in RP materials, outlines the challenges, and presents corresponding countermeasures aimed to enhance the electrochemical performance. It covers aspects such as the structural design of RP, the choice of the additive materials and electrolytes, rational electrode construction, etc. The review also discusses the future prospects of RP for LIBs/SIBs and aims to provide a different perspective on the challenges that must be overcome to fully exploit the potential of RP and meet commercial application requirements.