bluuebunny/crossref_metadata_2025 huggingface dataset:
The More You Say, the Less They Hear
Authors: Asbeek Brusse Elsbeth D. , Fransen Marieke L. , Smit Edith G.
Published: February 2015

Abstract. This study examined the effects of disclosure messages in entertainment-education (E-E) on attitudes toward hearing protection and attitude toward the source. In addition, the (mediating) role of the underlying mechanisms (i.e., transportation, identification, and counterarguing) was studied. In an experiment (N = 336), three different disclosure messages were compared with a no-disclosure condition. The results show that more explicit disclosure messages negatively affect transportation and identification and stimulate the generation of counterarguments. In addition, the more explicit disclosure messages affect both attitude measures via two of these processes (i.e., transportation and counterarguing). Less explicit disclosure messages do not have this effect. Implications of the findings are discussed.
Effects of Right-Wing Populist Political Advertising on Implicit and	Explicit Stereotypes
Authors: Arendt Florian , Marquart Franziska , Matthes Jörg
Published: February 2015

Abstract. We investigated the effects of antiforeigner political advertisements on implicit and explicit stereotypes. While stereotypical associations may become automatically activated (implicit stereotypes), individuals can reject these thoughts and decide not to use them for an overtly expressed judgment (explicit stereotypes). We hypothesized that even if citizens negated stereotypical content, advertisements might still affect implicit stereotypes. This hypothesis was tested using an experiment where participants (N = 186) were exposed to zero, two, four, or six stereotypical advertisements. The results showed that stereotypical advertisements did not influence explicit stereotypes but did influence implicit stereotypes, even in critical recipients who negated the stereotypical content.
CD244 is expressed on dendritic cells and regulates their functions
Authors: Georgoudaki Anna‐Maria , Khodabandeh Sorosh , Puiac Speranta , Persson Catrine M , Larsson Maria K , Lind Max , Hammarfjord Oscar , Nabatti Tara H , Wallin Robert P A , Yrlid Ulf , Rhen Mikael , Kumar Vinay , Chambers Benedict J
Published: February 2015

Signaling lymphocytic activation molecule (SLAM) receptors have an important role in the development of immune responses because of their roles, for exampe, in NK cell cytotoxicity and cytokine production by NK, T cells and myeloid cells. The SLAM receptor CD244 (2B4, SLAMf4) is expressed on a variety of immune cell types but most of its functions have been examined on NK and T cells. In the present study, we investigated expression and function of CD244 in murine subsets of dendritic cells (DCs). We report that all subsets of murine DCs examined expressed CD244, although the expression levels of CD244 varied between subsets. Splenic and resident mesenteric lymph node (MLN) DCs from CD244−/− mice expressed lower levels of CD86 and MHC class II compared with wild‐type mice. Upon Toll‐like receptor (TLR) stimulation, no differences in surface expression of these molecules were observed between DCs from CD244−/− and wild‐type mice. However, splenic DCs from CD244−/− mice upon stimulation with TLR binding ligands lipopolysaccharide (LPS) and CpG produced significantly higher levels of pro‐inflammatory cytokines. In addition, DCs from CD244−/− mice elicited increased NK cell activation in vitro. These data add CD244 to a growing list of immuno‐modulatory receptors found on DCs.
Transcription factor‐mediated reprogramming: epigenetics and therapeutic potential
Authors: Firas Jaber , Liu Xiaodong , Lim Sue Mei , Polo Jose M
Published: February 2015

Cellular reprogramming refers to the conversion of one cell type into another by altering its epigenetic marks. This can be achieved by three different methods: somatic cell nuclear transfer, cell fusion and transcription factor (TF)‐mediated reprogramming. TF‐mediated reprogramming can occur through several means, either reverting backwards to a pluripotent state before redifferentiating to a new cell type (otherwise known as induced pluripotency), by transdifferentiating directly into a new cell type (bypassing the intermediate pluripotent stage), or, by using the induced pluripotency pathway without reaching the pluripotent state. The possibility of reprogramming any cell type of interest not only sheds new insights on cellular plasticity, but also provides a novel use of this technology across several platforms, most notably in cellular replacement therapies, disease modelling and drug screening. This review will focus on the different ways of implementing TF‐mediated reprogramming, their associated epigenetic changes and its therapeutic potential.
Human olfactory receptor responses to odorants
Authors: Mainland Joel D , Li Yun R , Zhou Ting , Liu Wen Ling L , Matsunami Hiroaki
Published: February 2015

Although the human olfactory system is capable of discriminating a vast number of odors, we do not currently understand what chemical features are encoded by olfactory receptors. In large part this is due to a paucity of data in a search space covering the interactions of hundreds of receptors with billions of odorous molecules. Of the approximately 400 intact human odorant receptors, only 10% have a published ligand. Here we used a heterologous luciferase assay to screen 73 odorants against a clone library of 511 human olfactory receptors. This dataset will allow other researchers to interrogate the combinatorial nature of olfactory coding.
The pediatric template of brain perfusion
Authors: Avants Brian B , Duda Jeffrey T , Kilroy Emily , Krasileva Kate , Jann Kay , Kandel Benjamin T , Tustison Nicholas J , Yan Lirong , Jog Mayank , Smith Robert , Wang Yi , Dapretto Mirella , Wang Danny J J
Published: February 2015

Magnetic resonance imaging (MRI) captures the dynamics of brain development with multiple modalities that quantify both structure and function. These measurements may yield valuable insights into the neural patterns that mark healthy maturation or that identify early risk for psychiatric disorder. The Pediatric Template of Brain Perfusion (PTBP) is a free and public neuroimaging resource that will help accelerate the understanding of childhood brain development as seen through the lens of multiple modality neuroimaging and in relation to cognitive and environmental factors. The PTBP uses cross-sectional and longitudinal MRI to quantify cortex, white matter, resting state functional connectivity and brain perfusion, as measured by Arterial Spin Labeling (ASL), in 120 children 7–18 years of age. We describe the PTBP and show, as a demonstration of validity, that global summary measurements capture the trajectories that demarcate critical turning points in brain maturation. This novel resource will allow a more detailed understanding of the network-level, structural and functional landmarks that are obtained during normal adolescent brain development.
Long-term efficacy and safety of omalizumab in patients with persistent uncontrolled allergic asthma: a systematic review and meta-analysis
Authors: Lai Tianwen , Wang Shaobin , Xu Zhiwei , Zhang Chao , Zhao Yun , Hu Yue , Cao Chao , Ying Songmin , Chen Zhihua , Li Wen , Wu Bin , Shen Huahao
Published: February 2015

Currently, limited information is available to clinicians regarding the long-term efficacy of omalizumab treatment for allergic asthma. In this report, we aimed to (i) systematically review the evidence regarding the long-term efficacy of omalizumab in patients with persistent uncontrolled allergic asthma and to (ii) discuss the cost-effectiveness evidence published for omalizumab in this patient population. A comprehensive search for randomized controlled trials (RCTs; ≥52 weeks) was performed and six studies met our final inclusion criteria (n = 2,749). Omalizumab was associated with significant improvements in quality of life and the Global Evaluation of Treatment Effectiveness. Omalizumab also allowed patients to completely withdraw from inhaled corticosteroid therapy and did not increase the overall incidence of adverse events. However, there was insufficient evidence that omalizumab reduced the incidence of exacerbations and the cost-effectiveness of omalizumab varied across studies. Our data indicated that omalizumab use for at least 52 weeks in patients with persistent uncontrolled allergic asthma was accompanied by an acceptable safety profile, but it lacked effect on the asthma exacerbations. Use of omalizumab was associated with a higher cost than conventional therapy, but these increases may be cost-effective if the medication is used in patients with severe allergic asthma.
Crystal structure of UbiX, an aromatic acid decarboxylase from the psychrophilic bacterium Colwellia psychrerythraea that undergoes FMN-induced conformational changes
Authors: Do Hackwon , Kim Soo Jin , Lee Chang Woo , Kim Han-Woo , Park Hyun Ho , Kim Ho Min , Park Hyun , Park HaJeung , Lee Jun Hyuck
Published: February 2015

The ubiX gene of Colwellia psychrerythraea strain 34H encodes a 3-octaprenyl-4-hydroxybenzoate carboxylase (CpsUbiX, UniProtKB code: Q489U8) that is involved in the third step of the ubiquinone biosynthesis pathway and harbors a flavin mononucleotide (FMN) as a potential cofactor. Here, we report the crystal structures of two forms of CpsUbiX: an FMN-bound wild type form and an FMN-unbound V47S mutant form. CpsUbiX is a dodecameric enzyme and each monomer possesses a typical Rossmann-fold structure. The FMN-binding domain of UbiX is composed of three neighboring subunits. The highly conserved Gly15, Ser41, Val47 and Tyr171 residues play important roles in FMN binding. Structural comparison of the FMN-bound wild type form with the FMN-free form reveals a significant conformational difference in the C-terminal loop region (comprising residues 170–176 and 195–206). Subsequent computational modeling and liposome binding assay both suggest that the conformational flexibility observed in the C-terminal loops plays an important role in substrate and lipid bindings. The crystal structures presented in this work provide structural framework and insights into the catalytic mechanism of CpsUbiX.
Interaction of Pseudostellaria heterophylla with Fusarium oxysporum f.sp. heterophylla mediated by its root exudates in a consecutive monoculture system
Authors: Zhao Yongpo , Wu Linkun , Chu Leixia , Yang Yanqiu , Li Zhenfang , Azeem Saadia , Zhang Zhixing , Fang Changxun , Lin Wenxiong
Published: February 2015

In this study, quantitative real-time PCR (qPCR) was used to determine the amount of Fusarium oxysporum, an important replant disease pathogen in Pseudostellaria heterophylla rhizospheric soil. Moreover, HPLC was used to identify phenolic acids in root exudates then it was further to explore the effects of the phenolic acid allelochemicals on the growth of F. oxysporum f.sp. heterophylla. The amount of F. oxysporum increased significantly in P. heterophylla rhizosphere soil under a consecutive replant system as monitored through qPCR analysis. Furthermore, the growth of F. oxysporum f.sp. heterophylla mycelium was enhanced by root exudates with a maximum increase of 23.8%. In addition, the number of spores increased to a maximum of 12.5-fold. Some phenolic acids promoted the growth of F. oxysporum f.sp. heterophylla mycelium and spore production. Our study revealed that phenolic acids in the root secretion of P. heterophylla increased long with its development, which was closely related to changes in rhizospheric microorganisms. The population of pathogenic microorganisms such as F. oxysporum in the rhizosphere soil of P. heterophylla also sharply increased. Our results on plant-microbe communication will help to better clarify the cause of problems associated with P. heterophylla under consecutive monoculture treatment.
A 2D-DIGE-based proteomic analysis reveals differences in the platelet releasate composition when comparing thrombin and collagen stimulations
Authors: Vélez Paula , Izquierdo Irene , Rosa Isaac , García Ángel
Published: February 2015

Upon stimulation, platelets release a high number of proteins (the releasate). There are clear indications that these proteins are involved in the pathogenesis of several diseases, such as atherosclerosis. In the present study we compared the platelet releasate following platelet activation with two major endogenous agonists: thrombin and collagen. Proteome analysis was based on 2D-DIGE and LC-MS/MS. Firstly, we showed the primary role of thrombin and collagen receptors in platelet secretion by these agonists; moreover, we demonstrated that GPVI is the primary responsible for collagen-induced platelet activation/aggregation. Proteomic analysis allowed the detection of 122 protein spots differentially regulated between both conditions. After excluding fibrinogen spots, down-regulated in the releasate of thrombin-activated platelets, 84 differences remained. From those, we successfully identified 42, corresponding to 37 open-reading frames. Many of the differences identified correspond to post-translational modifications, primarily, proteolysis induced by thrombin. Among others, we show vitamin K-dependent protein S, an anticoagulant plasma protein, is up-regulated in thrombin samples. Our results could have pathological implications given that platelets might be playing a differential role in various diseases and biological processes through the secretion of different subsets of granule proteins and microvesicles following a predominant activation of certain receptors.
The fate of recent duplicated genes following a fourth-round whole genome duplication in a tetraploid fish, common carp (Cyprinus carpio)
Authors: Li Jiong-Tang , Hou Guang-Yuan , Kong Xiang-Fei , Li Chun-Yan , Zeng Jian-Ming , Li Heng-De , Xiao Gui-Bao , Li Xiao-Min , Sun Xiao-Wen
Published: February 2015

Whole genome duplication (WGD) results in extensive genetic redundancy. In plants and yeast, WGD is followed by rapid gene deletions and intense expression differentiation with slow functional divergence. However, the early evolution of the gene differentiation processes is poorly understood in vertebrates because almost all studied WGDs are extremely ancient and the genomes have returned to a diploid status. Common carp had a very recent fourth round of WGD dated to 8 million years ago. It therefore constitutes an ideal model to study early-stage functional divergence and expression differentiation in vertebrates. We identified 1,757 pairs of recently duplicated genes (RDGs) originating from this specific WGD and found that most ancestral genes were retained in duplicate. Most RDGs were conserved and under selective pressure. Gene expression analysis across six tissues revealed that 92.5% of RDG pairs were co-expressed in at least one tissue and that the expression of nearly half pairs ceased to be strongly correlated, indicating slow spatial divergence but rapid expression dissociation. Functional comparison revealed that 25% of pairs had functional divergence, of which neo- and sub-functionalization were the main outcomes. Our analysis revealed slow gene loss but rapid and intense expression and function differentiation after WGD.
Homo-β-amino acid containing MBP(85–99) analogs alleviate experimental autoimmune encephalomyelitis
Authors: Kant Ravi , Pasi Shweta , Surolia Avadhesha
Published: February 2015

MBP(85–99), an immuno-dominant epitope of myelin basic protein which binds to the major histocompatibility complex haplotype HLA-DR2 is widely implicated in the pathogenesis of multiple sclerosis. J5, an antagonist of MBP(85–99), that blocks the binding of MBP(85–99) to soluble HLA-DR2b much more efficiently than glatiramer acetate (a random copolymer comprising major MHC and T-cell receptor contact residues), was transformed into analogs with superior biological half-lives and antagonistic-activities by substitution of some of its residues with homo-β-amino acids. S18, the best analog obtained ameliorated symptoms of experimental autoimmune encephalomyelitis at least twice more effectively than glatiramer acetate or J5. S18 displayed marked resistance to proteolysis in-vitro; biological impact of which was evident in the form of delayed clinical onset of disease and prolonged therapeutic-benefits. Besides active suppression of MBP(85–99)-reactive CD4+ T-cells in-vitro and in-vivo S18 treatment also generated IL-4 producing CD4+ T-cell clones, through which protective effect could be transferred passively.
In PC3 prostate cancer cells ephrin receptors crosstalk to β1-integrins to strengthen adhesion to collagen type I
Authors: Yu Miao , Wang Jinghe , Muller Daniel J. , Helenius Jonne
Published: February 2015

Eph receptor (Eph) and ephrin signaling can play central roles in prostate cancer and other cancer types. Exposed to ephrin-A1 PC3 prostate cancer cells alter adhesion to extracellular matrix (ECM) proteins. However, whether PC3 cells increase or reduce adhesion and by which mechanisms they change adhesion to the ECM remains to be characterized. Here, we assay how ephrin-A1 stimulates PC3 cells to adhere to ECM proteins using single-cell force spectroscopy. We find that PC3 cells binding to immobilized ephrin-A1 but not to solubilized ephrin-A1 specifically strengthen adhesion to collagen I. This Eph-ephrin-A1 signaling, which we suppose is based on mechanotransduction, stimulates β1-subunit containing integrin adhesion via the protein kinase Akt and the guanine nucleotide-exchange factor cytohesin. Inhibiting the small GTPases, Rap1 or Rac1, generally lowered adhesion of PC3 prostate cancer cells. Our finding suggests a mechanism by which PC3 prostate cancer cells exposed to ephrins crosstalk to β1-integrins and preferably metastasize in bone, a collagen I rich tissue.
Giant local circular dichroism within an asymmetric plasmonic nanoparticle trimer
Authors: Wang Hancong , Li Zhipeng , Zhang Han , Wang Peijie , Wen Shuangchun
Published: February 2015

We investigated the near-field response in silver nanoparticle aggregates to the excitation of circular polarized light. In a right-angle trimer system, the local field intensity excited by right-hand circularly polarized light is almost one thousand times larger than the left-hand case. By analyzing the polarization and phase of the local field in plasmonic hotspots, we found this local circular dichroism is originated from the near-field interference excited by orthogonal polarized incident lights. The local circular dichroism can be tuned by the rotation of the third particle, the interparticle distance and the dielectric environment. This phenomenon could also widely exist in more complicated nanoaggregates. These findings would benefit for resolving light handedness and enhancing circular dichroism and optical activity.
Measurement and mitigation of nitrous oxide emissions from a high nitrogen input vegetable system
Authors: Lam Shu Kee , Suter Helen , Davies Rohan , Bai Mei , Sun Jianlei , Chen Deli
Published: February 2015

The emission and mitigation of nitrous oxide (N2O) from high nitrogen (N) vegetable systems is not well understood. Nitrification inhibitors are widely used to decrease N2O emissions in many cropping systems. However, most N2O flux measurements and inhibitor impacts have been made with small chambers and have not been investigated at a paddock-scale using micrometeorological techniques. We quantified N2O fluxes over a four ha celery paddock using open-path Fourier Transform Infrared spectroscopy in conjunction with a backward Lagrangian stochastic model, in addition to using a closed chamber technique. The celery crop was grown on a sandy soil in southern Victoria, Australia. The emission of N2O was measured following the application of chicken manure and N fertilizer with and without the application of a nitrification inhibitor 3, 4-dimethyl pyrazole phosphate (DMPP). The two techniques consistently demonstrated that DMPP application reduced N2O emission by 37–44%, even though the N2O fluxes measured by a micrometeorological technique were more than 10 times higher than the small chamber measurements. The results suggest that nitrification inhibitors have the potential to mitigate N2O emission from intensive vegetable production systems and that the national soil N2O emission inventory assessments and modelling predictions may vary with gas measurement techniques.
Versatile G-quadruplex-mediated strategies in label-free biosensors and logic systems
Authors: Ren Jiangtao , Wang Tianshu , Wang Erkang , Wang Jin
Published: February 2015

This review addresses how G-quadruplex (G4)-mediated biosensors convert the events of target recognition into a measurable physical signal. The application of label-free G4-strategies in the construction of logic systems is also discussed.
Making colourful sense of Raman images of single cells
Authors: Ashton Lorna , Hollywood Katherine A. , Goodacre Royston
Published: February 2015

We demonstrate how changes in the application of colour shading can dramatically alter Raman images of single human keratinocytes cells.
Starch (Tapioca) to carbon dots: an efficient green approach to an on–off–on photoluminescence probe for fluoride ion sensing
Authors: Basu Aniruddha , Suryawanshi Anil , Kumawat Begraj , Dandia Anshu , Guin Debanjan , Ogale Satishchandra B.
Published: February 2015

Photoluminescent carbon dots are synthesized from starch (Tapioca) and are shown to work effectively as anion-selective fluoride ion probes based on Fe3+ induced photoluminescence quenching and F− induced recovery.
A narrow-bandgap benzobisthiadiazole derivative with high near-infrared photothermal conversion efficiency and robust photostability for cancer therapy
Authors: Huang Shuo , Kannadorai Ravi Kumar , Chen Yuan , Liu Quan , Wang Mingfeng
Published: February 2015

A novel photothermal therapeutic agent based on a narrow-bandgap benzobisthiadiazole derivative shows strong absorption in the near-infrared region, high photothermal efficiency and robust photostability for treatment of cancer cells.
Copper-catalyzed direct α-ketoesterification of propiophenones with acetophenones via C(sp3)–H oxidative cross-coupling
Authors: Du Juan , Zhang Xiuli , Sun Xi , Wang Lei
Published: February 2015

A Cu-catalyzed direct α-ketoesterification of propiophenones with acetophenones via C(sp3)–H oxidative cross-coupling was developed by using O2 as an oxidant.
Mirror symmetry breaking upon spontaneous crystallization from a dynamic combinatorial library of macrocyclic imines
Authors: Ziach Krzysztof , Jurczak Janusz
Published: February 2015

Spontaneous emergence of chirality upon crystallization from small DCL.
Vinylogy in nitronates: utilization of α-aryl conjugated nitroolefins as a nucleophile for a highly stereoselective aza-Henry reaction
Authors: Oyaizu Keigo , Uraguchi Daisuke , Ooi Takashi
Published: February 2015

Vinylogous nitronates generated from α,β-disubstituted nitroolefins undergo stereoselective bond formation with aldimines at the sterically encumbered α-position, establishing contiguous tertiary–quaternary stereocenters.
Copper-catalyzed radical cascade cyclization for the synthesis of phosphorated indolines
Authors: Zhang Hong-Yu , Mao Liu-Liang , Yang Bin , Yang Shang-Dong
Published: February 2015

A novel and convenient approach to the synthesis of various phosphorated indolinesviaa copper-catalyzed radical cascade cyclization reaction has been developed.
Selective functionalization of methylene bridges of calix[6]arenes. Isolation and identification of stable conformers of methyl ether of p-tert-butylcalix[6]arene
Authors: Arora Shafali , Sharma Shivali , Mithu Venus S. , Hee-Lee Chang , Singh Kamaljit
Published: February 2015

A direct regioselective metalation–substitution sequence furnished stable, symmetrically methylene bridge disubstituted calix[6]arenemethyl ether in distorted cone and 1,2,3-alternate conformations.
Sugar and pH dual-responsive snap-top nanocarriers based on mesoporous silica-coated Fe3O4magnetic nanoparticles for cargo delivery
Authors: Qiu Xi-Long , Li Qing-Lan , Zhou Yue , Jin Xiao-Yu , Qi Ai-Di , Yang Ying-Wei
Published: February 2015

Sugar and pH operated snap-top nanocarriers, consisting of a superparamagnetic Fe3O4core and a mesoporous silica shell and surface-functionalized covalently with β-CDs, were constructed.
Open-framework beryllium phosphates with a zeolitic CrB4 topology and their structural analogues containing 12-ring channels
Authors: Wang Kangcai , Li Jing , Xu Dingguo , Luo Daibing , Lin Zhien
Published: February 2015

Two 16-membered-ring beryllium phosphates with a zeolitic CrB4 topology have been prepared under solvothermal conditions, which contain in situ generated viologen ions from the alkylation of 4,4′-bipyridine molecules.
On the lag phase in amyloid fibril formation
Authors: Arosio Paolo , Knowles Tuomas P. J. , Linse Sara
Published: February 2015

Rates of microscopic processes taking place during the lag phase of amyloid fibril formation for a reaction starting from an initially monomeric 4 μm solution of Aβ42.
Improved photoelectrochemical water oxidation kinetics using a TiO2 nanorod array photoanode decorated with graphene oxide in a neutral pH solution
Authors: Chae Sang Youn , Sudhagar Pitchaimuthu , Fujishima Akira , Hwang Yun Jeong , Joo Oh-Shim
Published: February 2015

Opposite contributions of graphene oxide are obtained in TiO2 nanorod array photoanodes, in electrolytes of varying pH, for the water splitting application. The photocurrent of TiO2 photoanode is improved, after graphene oxide coating, in a neutral pH electrolyte, while it decreases in a basic electrolyte.
Competitive 13C and 18O kinetic isotope effects on CO2 reduction catalyzed by Re(bpy)(CO)3Cl
Authors: Schneider Taylor W. , Angeles-Boza Alfredo M.
Published: February 2015

Competitive 13C and 18O kinetic isotope effects (KIEs) on CO2 reduction reactions catalyzed by Re(bpy)(CO)3Cl are reported.
On the gold–ligand covalency in linear [AuX2]− complexes
Authors: Xiong Xiao-Gen , Wang Yi-Lei , Xu Cong-Qiao , Qiu Yi-Heng , Wang Lai-Sheng , Li Jun
Published: February 2015

Gold compounds, clusters, and nanoparticles are widely used as catalysts and therapeutic medicines; the bonding interactions between gold and its ligands in these systems play important roles in their chemical properties and functionalities.
Development of Ag nanopolyhedra based fiber-optic probes for high performance SERS detection
Authors: Cao Jie , Wang Jinzu
Published: February 2015

Tapered fiber probes based on silver nanopolyhedra were fabricated using a direct and effective autoclave reaction method and exhibited high SERS activity.
Reply to the ‘Comment on “The role of electrostatic induction in secondary isotope effects on acidity”’ by C. L. Perrin, New J. Chem., 2015, 39, DOI: 10.1039/C4NJ01887G
Authors: Amitai Halevi E.
Published: February 2015

Shifts of harmonic frequencies suffice to explain isotope effects, but it does not follow that vibrational anharmonicity can be neglected.
Effect of surface roughness on substrate-tuned gold nanoparticle gap plasmon resonances
Authors: Lumdee Chatdanai , Yun Binfeng , Kik Pieter G.
Published: February 2015

The impact of nanoscale surface roughness on substrate-tuned gold nanoparticle plasmon resonances is demonstrated by comparing single-particle scattering spectra with simulated scattering spectra of gold nanoparticles on gold films with realistic roughness.
Reconciling order, stability, and porosity in phosphonate metal–organic frameworks via HF-mediated synthesis
Authors: Mah Roger K. , Gelfand Benjamin S. , Taylor Jared M. , Shimizu George K. H.
Published: February 2015

We report the use of an HF-mediated synthesis to control porosity and order in robust Zr phosphonate frameworks.
Phase-transfer-catalyzed asymmetric desymmetrizations of cyclopentanones
Authors: Shirakawa Seiji , Tokuda Takashi , Kan S. B. Jennifer , Maruoka Keiji
Published: February 2015

Highly enantioselective phase-transfer-catalyzed epoxide-opening reaction and isomerization of cyclopentanones were achieved.
Nickel ferrite nanoparticles: an efficient and reusable nanocatalyst for a neat, one-pot and four-component synthesis of pyrroles
Authors: Moghaddam Firouz Matloubi , Koushki Foroushani Behzad , Rezvani Hamid Reza
Published: February 2015

We applied magnetic NiFe2O4 as a recoverable catalyst in the multicomponent reaction of substituted pyrroles. Magnetic NiFe2O4 could be recovered from the reaction easily with an external magnet and reused nine times without significant activity loss. The yields are high.
Synthesis and evaluation of the antitumor activity of polyhalo acridone derivatives
Authors: Huang Chao , Yan Sheng-Jiao , Zeng Xiang-Hui , Sun Bo , Lan Min-Bo , Lin Jun
Published: February 2015

A series of polyhalo acridone heterocyclic compounds were synthesized and evaluated for theirin vitroantitumor activity. Compounds4d,4o,5jand5kshowed good antineoplastic selectivity.
Utilization of Ru(ii)-complex immobilized ZnO hybrid in presence of Pt(ii) co-catalyst for photocatalytic reduction of 4-nitrophenol under visible light
Authors: Bhar Sumana , Ananthakrishnan Rajakumar
Published: February 2015

In the present study, an attempt has been made to utilize a Ru(ii)-complex-sensitized ZnO hybrid along with a Pt(ii) salt for the visible light aided photoreduction of 4-nitrophenol.
Glycosylation of polyphosphazenes by thiol-yne click chemistry for lectin recognition
Authors: Chen Chen , Xu Huang , Qian Yue-Cheng , Huang Xiao-Jun
Published: February 2015

Strong carbohydrate–lectin binding interactions in biological systems can be mimicked through the synthesis of glucose containing macromolecules, particularly glycosylated polymers.
Effects of added thiol ligand structure on aggregation of non-aqueous ZnO dispersions and morphology of spin-coated films
Authors: Mispelon Aloïs , Yan Junfeng , Milani Amir H. , Chen Mu , Wang Wenkai , O'Brien Paul , Saunders Brian R.
Published: February 2015

The structure of bidentate thiol ligands controls dispersion aggregation and enables spin coating of ZnO films with enhanced light scattering.
Uniform copper oxide–poly(m-phenylenediamine) microflowers: synthesis and application for the adsorption of methyl orange
Authors: Guo Tingting , Kang Xinyuan , Zhang Tingting , Liao Fang
Published: February 2015

A CuO–PmPD flower-like composite synthesised in one step exhibit a superior adsorption capacity for MO.
Facile identification of the critical content of multi-layer graphene oxide for epoxy composite with optimal thermal properties
Authors: Zhou Tianle , Nagao Shijo , Sugahara Tohru , Koga Hirotaka , Nogi Masaya , Suganuma Katsuaki , Nge Thi Thi , Nishina Yuta
Published: February 2015

A strategy to rapidly identify the critical content of multi-layer graphene oxide for epoxy composite with the optimal thermal properties.
Silver ion post-column derivatization electrospray ionization mass spectrometry for determination of tetrabromobisphenol A derivatives in water samples
Authors: Tian Yong , Liu Ai-feng , Qu Guang-bo , Liu Chun-xiao , Chen Jian , Handberg Eric , Shi Jian-bo , Chen Huan-wen , Jiang Gui-bin
Published: February 2015

Six TBBPA derivatives in water samples were sensitively electrospray ionized by Ag+ post-column derivatization and directly analyzed with HPLC-MS/MS.
Sol–gel synthesis and room-temperature properties of α-LiZr2(PO4)3
Authors: El-Shinawi Hany , Greaves Colin , Janek Jürgen
Published: February 2015

A room-temperature stable α-LiZr2(PO4)3 phase is prepared by a modified sol–gel method, and shows bulk conductivity as high as 1.58 × 10−4 Scm−1.
Luminescent properties of Ag(i)/Cu(i) coordination polymers: crystal structures and high intensity luminescence of a PMMA-doped hybrid material based on a quinoline-2,3-dicarboxylic acid ligand
Authors: Song Yang , Fan Rui-Qing , Zhang Hui-Jie , Liu Zhi-Wei , Wang Xue-Tao , Tan Cai-Tu , Yang Yu-Lin , Wang Yu-Lei
Published: February 2015

Preparation, characterization, crystal structure and different luminescent properties of Ag(i)/Cu(i) coordination polymers: stable blue emission, thermochromism and PMMA-doped hybrid material.
In situ optical emission spectroscopy diagnostics of glow discharges in SiH4/GeH4/H2
Authors: Wang Guanghong , Shi Chengying , Hu Ruidan , Zhao Lei , Wang Ge , Diao Hongwei , Wang Wenjing
Published: February 2015

An optical emission spectroscopic study identifies transient and steady-state behavior of the excited H*α/H*β/SiH*/GeH* emission in parallel plate SiH4/GeH4/H2 plasma.
TBHP mediated oxidation of N-2-alkynylphenyl α-amino carbonyl compounds to oxalic amides using visible light photoredox catalysis and their application in the synthesis of 2-aryl indoles
Authors: Liu Wei , Liu Sheng , Xie Hongqi , Qing Zhixing , Zeng Jianguo , Cheng Pi
Published: February 2015

Visible light promoted the oxidation of compounds 1 to amides 2 which were easily transferred to compounds 12.
Long-range two-photon scattering spectroscopy ruler for screening prostate cancer cells
Authors: Sinha Sudarson Sekhar , Paul Dilip K. , Kanchanapally Rajashekhar , Pramanik Avijit , Chavva Suhash Reddy , Viraka Nellore Bhanu Priya , Jones Stacy J. , Ray Paresh Chandra
Published: February 2015

Development of a long-range TPS ruler for the screening of prostate cancer cells with sensitivity of 5 cells per mL level is demonstrated.
Synthesis and reactivity of cyclo-tetra(stibinophosphonium) tetracations: redox and coordination chemistry of phosphine–antimony complexes
Authors: Chitnis Saurabh S. , Robertson Alasdair P. M. , Burford Neil , Weigand Jan J. , Fischer Roland
Published: February 2015

Reactions of trialkylphosphines with antimony(iii) triflates yieldcatena-antimony(i) cations revealing a new reductive elimination/oxidative coupling reaction for P–Sb coordination complexes.
Synthesis and catalytic properties of multilayered MEL-type titanosilicate nanosheets
Authors: Chen Hong Li , Li Shang Wei , Wang Yi Meng
Published: February 2015

Multilayered MTS-2 were synthesized using binary templates and they exhibited improved catalytic activities in the hydroxylation and epoxidation of bulky molecules.
Enhanced adsorption removal of methyl orange from aqueous solution by nanostructured proton-containing δ-MnO2
Authors: Liu Yan , Luo Chao , Sun Jian , Li Haizhen , Sun Zebin , Yan Shiqiang
Published: February 2015

Two nanostructured proton-containing δ-MnO2 (H-δ-MnO2) materials were synthesized through proton exchange for K-containing δ-MnO2 (K-δ-MnO2) nanosheets and nanoparticles prepared by the hydrothermal homogeneous precipitation method and solid-state reaction.
3,6-Bis(1-methyl-4-vinylpyridinium)-carbazole diiodide as a marker for tracking living neural stem/precursor cells
Authors: Li Yi-Chen , Wang Jyh-Horng , Tsai Li-Kai , Chen Yun-An , Chang Ta-Chau , Lou Pei-Jen , Young Tai-Horng
Published: February 2015

A novel compound, 3,6-bis(1-methyl-4-vinylpyridinium)-carbazole diiodide, is used as a marker for distinguishing living neural stem/precursor cells (NSPCs) from adipose-derived stem cells (ADSCs) and bone marrow mesenchymal stem cells (BMMSCs).
Formulation of robust organic–inorganic hybrid magnetic microcapsules through hard-template mediated method for efficient enzyme immobilization
Authors: Hou Chen , Wang Yang , Zhu Hao , Zhou Lincheng
Published: February 2015

Fabrication of robust organic–inorganic hybrid magnetic microcapsules coordinated with polydopamine and Fe3O4 nanoparticles for enzyme immobilization.
CuMo0.9W0.1O4 phase transition with thermochromic, piezochromic, and thermosalient effects
Authors: Robertson L. , Penin N. , Blanco-Gutierrez V. , Sheptyakov D. , Demourgues A. , Gaudon M.
Published: February 2015

This study deals with the structural investigation by neutron diffraction of the CuMo0.9W0.1O4 compound phase transition, associated with thermochromic, piezochromic, and thermosalient effects.
Free-standing, flexible thermochromic films based on one-dimensional magnetic photonic crystals
Authors: Ma Huiru , Zhu Mingxing , Luo Wei , Li Wei , Fang Kai , Mou Fangzhi , Guan Jianguo
Published: February 2015

Instant radical polymerization of sterically stabilized magnetically responsive photonic crystal nonaqueous suspensions under magnetic field can obtain flexible thermochromic free-standing films, which display bright iridescent colors strongly sensitive to temperature with good reversibility and durability.
Lanthanide ions (Eu3+, Tb3+, Sm3+, Dy3+) activated ZnO embedded zinc 2,5-pyridinedicarboxylic metal–organic frameworks for luminescence application
Authors: Duan Tian-Wei , Yan Bing
Published: February 2015

A series of hybrids based on lanthanide ions activated zinc metallic organic frameworks of 2,5-pyridinedicarboxylate (ZnO@Zn(pdc)-Ln, Ln = Eu, Tb, Sm, Dy) have been synthesized by forming ZnO.
Self-assembly of an organic–inorganic hybrid nanoflower as an efficient biomimetic catalyst for self-activated tandem reactions
Authors: Huang Yanyan , Ran Xiang , Lin Youhui , Ren Jinsong , Qu Xiaogang
Published: February 2015

An organic–inorganic hybrid nanoflower was prepared as an efficient biomimetic catalyst with excellent catalytic activity, durability and stability.
An injectable thermogel with high radiopacity
Authors: Lei Kewen , Shen Wenjia , Cao Luping , Yu Lin , Ding Jiandong
Published: February 2015

An injectable thermogel with high X-ray opacity was designed and synthesized for the first time and such a system shows great potential in non-invasive diagnosis and therapy.
Differential interactions of conjugated polymer nanoparticles with glycosaminoglycans in synthetic urine
Authors: Twomey Megan , Vokatá Tereza , Kumar Manian Rajesh , Moon Joong Ho
Published: February 2015

Structurally diverse conjugated polymers nanoparticles (CPNs) are sensitive and effective at differentiating structurally similar glycosaminoglycans (GAGs) in a urine simulant.
Oligonucleotides containing a piperazino-modified 2′-amino-LNA monomer exhibit very high duplex stability and remarkable nuclease resistance
Authors: Lou Chenguang , Vester Birte , Wengel Jesper
Published: February 2015

Incorporation of a novel piperazino-modified 2′-amino-LNA monomer (PipLNA-T) into oligonucleotides leads to a pronounced affinity increase against complementary DNA and RNA and a strong stabilising effect against 3′-exonucleolytic degradation.
Highly fluorescent one-handed nanotubes assembled from a chiral asymmetric perylene diimide
Authors: Ma Xiaojie , Zhang Yibin , Zheng Yingxuan , Zhang Yifan , Tao Xia , Che Yanke , Zhao Jincai
Published: February 2015

Highly fluorescent bilayer nanotubes with a right- or left-handed helical sense were assembled from a chiral asymmetric perylene diimide.
Oxidative Heck desymmetrisation of 2,2-disubstituted cyclopentene-1,3-diones
Authors: Walker S. E. , Lamb C. J. C. , Beattie N. A. , Nikodemiak P. , Lee A.-L.
Published: February 2015

Oxidative Heck couplings have been successfully developed for 2,2-disubstituted cyclopentene-1,3-diones. The direct coupling onto the 2,2-disubstituted cyclopentene-1,3-dione core provides a novel, expedient and useful way of desymmetrising all-carbon quaternary centres.
A new mesoporous coordination polymer: synthesis, structure, and gas adsorption studies
Authors: Duan Jingui , Li QianQian , Lu Zhiyong
Published: February 2015

A new porous coordination framework, NJTU-1, with low binding energy and remarkable mesopores, exhibits a high surface area and excellent gas adsorption behavior at 298 K.
Quaternary ammonium hydroxide as a metal-free and halogen-free catalyst for the synthesis of cyclic carbonates from epoxides and carbon dioxide
Authors: Ema Tadashi , Fukuhara Kazuki , Sakai Takashi , Ohbo Masaki , Bai Fu-Quan , Hasegawa Jun-ya
Published: February 2015

Tetrabutylammonium hydroxide (TBAH) acted as a good catalyst for the formation of cyclic carbonates from epoxides and CO2 under solvent-free conditions.
Synthesis of Au–ZnO hybrid nanostructure arrays and their enhanced photocatalytic activity
Authors: Yuyang Sun , Long Jiang , Tian Zeng , Jin Wei , Ling Liu , Yong Jin , Zhifeng Jiao , Xiaosong Sun
Published: February 2015

The as-prepared Au–ZnO hybrid nanostructure exhibits superior photodegradation ability on methyl orange compared to the ZnO nanorod array without Au particles.
A phthalimide-based fluorescent probe for thiol detection with a large Stokes shift
Authors: Liu Xingjiang , Gao Li , Yang Liu , Zou Lifen , Chen Wenqiang , Song Xiangzhi
Published: February 2015

A phthalimide-based fluorescent probe for thiols with a large Stokes shift (161 nm) was developed via PET and ESIPT mechanisms. This probe displayed good selectivity and high sensitivity toward thiols. Imaging intracellular thiols was successfully achieved in living cells.
Lithium metatitanate enhanced solid–solid reaction in a lithium–nitrogen–hydrogen system
Authors: Zhang Tengfei , Isobe Shigehito , Wang Yongming , Hashimoto Naoyuki , Ohnuki Somei
Published: February 2015

In the Li–N–H system, an end temperature of under 260 °C was achieved, and the lowest peak temperature occurred at 223 °C.
Carbon nanofibers/nanosheets hybrid derived from cornstalks as a sustainable anode for Li-ion batteries
Authors: Wang Shengbin , Xiao Changlei , Xing Yalan , Xu Huaizhe , Zhang Shichao
Published: February 2015

A porous carbon nanofibers/nanosheets hybrid (CNFS) is converted from cornstalk waste, and displays a superhigh surface area and rich porosity. Benefiting from unique structural features, the evolved CNFS possesses an ultrahigh rate capability of 454 mA h g−1 at 3 A g−1.
Key renewal scheme with sensor authentication under clustered wireless sensor networks
Authors: Lee Saewoom , Kim Kiseon
Published: February 2015

In wireless sensor networks, the clustering routing protocol is commonly used for energy efficiency. However, routing protocols without proper security suffer from many security vulnerabilities. Hence, a key renewal scheme based on the clustering routing protocol is proposed. To apply the key renewal scheme with sensor authentication, sensor nodes are first authenticated during the key establishment procedure and then the symmetric key is updated periodically using hash functions. The simulation results show that the proposed key renewal scheme lengthens the network lifetime and has shorter activity time of attackers in spite of increasing the number of compromised nodes.
X‐band flexible bandpass filter based on ultra‐thin liquid crystal polymer substrate
Authors: Lan Yu , Xu Yuehang , Wang Changsi , Wen Zhang , Qiu Yijie , Mei Tengda , Wu Yunqiu , Xu Ruimin
Published: February 2015

The performance of an X‐band flexible band‐filter on ultra‐thin liquid crystal polymer (LCP) substrate is investigated. The 50 µm‐thick LCP substrate is adopted to enhance the flexibility of circuits. For the purpose of fabrication by the conventional printed circuit board process, copper‐clad laminate with 18 µm thickness is selected. Excellent microwave transmission characterisation is demonstrated by measuring the microstrip line at flat and bending conditions. An X‐band interdigital bandpass filter based on a half‐wavelength microstrip line resonator is designed and fabricated for purpose of demonstration. The measured results at the flat condition show that the insertion loss is 2.1 dB at centre frequency of 9.4 GHz and the return loss is better than 20 dB at the designed band. The performance at the bending condition shows that the bending effect causes little deterioration to the performance at a different bending radius.
Acute Spinal Subdural Hematoma after Vertebroplasty: A Case Report Emphasizing the Possible Etiologic Role of Venous Congestion
Authors: Mattei Tobias A. , Rehman Azeem A. , Dinh Dzung H.
Published: February 2015

Study Design

Case report and literature review.

Objective

Spinal subdural hematomas are rare events that often progress with severe neurologic deficits. Although there have been several case reports in the literature of spontaneous spinal subdural hematomas in the setting of anticoagulation, antiplatelet therapy, or coagulation disorders, the exact pathophysiology of such phenomena remains obscure.

Methods

We present the first report of a subdural hematoma after a percutaneous vertebroplasty and provide a comprehensive review on the anatomy of venous drainage of the vertebral bodies with emphasis on the possible effects of venous congestion caused by cement obstruction.

Results

Because the subdural hematoma occurred in the absence of major cement extravasation to the spinal canal and two levels above the site of the vertebroplasty, we discuss the possible role of venous congestion as the main etiologic factor leading to rupture of the fragile, valveless radiculomedullary veins into the subdural space.

Conclusions

The reported case supports a possible new pathophysiological scheme for the development of spinal subdural hematoma in which venous congestion plays a pivotal etiologic role. The reported findings suggests that future anatomical and histologic studies investigating the response of the radiculomedullary veins to congestive venous hypertension may shed new light into the pathophysiology of spinal subdural hematomas.
Spontaneous curvature of bilayer membranes from molecular simulations: Asymmetric lipid densities and asymmetric adsorption
Authors: Różycki Bartosz , Lipowsky Reinhard
Published: February 2015

Biomimetic and biological membranes consist of molecular bilayers with two leaflets which are typically exposed to different aqueous environments and may differ in their molecular density or composition. Because of these asymmetries, the membranes prefer to curve in a certain manner as quantitatively described by their spontaneous curvature. Here, we study such asymmetric membranes via coarse-grained molecular dynamics simulations. We consider two mechanisms for the generation of spontaneous curvature: (i) different lipid densities within the two leaflets and (ii) leaflets exposed to different concentrations of adsorbing particles. We focus on membranes that experience no mechanical tension and describe two methods to compute the spontaneous curvature. The first method is based on the detailed structure of the bilayer’s stress profile which can hardly be measured experimentally. The other method starts from the intuitive view that the bilayer represents a thin fluid film bounded by two interfaces and reduces the complexity of the stress profile to a few membrane parameters that can be measured experimentally. For the case of asymmetric adsorption, we introduce a simulation protocol based on two bilayers separated by two aqueous compartments with different adsorbate concentrations. The adsorption of small particles with a size below 1 nm is shown to generate large spontaneous curvatures up to about 1/(24 nm). Our computational approach is quite general: it can be applied to any molecular model of bilayer membranes and can be extended to other mechanisms for the generation of spontaneous curvatures as provided, e.g., by asymmetric lipid composition or depletion layers of solute molecules.
Frequency division color characterization apparatus for anisotropic leaky mode light modulators
Authors: Henrie A. , Haymore B. , Smalley D. E.
Published: February 2015

This paper presents an optical apparatus for characterizing frequency multiplexing of color in leaky mode, anisotropic waveguide modulators. This type of characterization is particularly useful for informing the design of full color holographic video displays. The primary function of the apparatus is to map the frequency response and angular overlap of red, green, and blue outputs. The apparatus also allows measurements of other parameters such as scan center frequency, optical and RF bandwidth, and scan linearity.