bluuebunny/crossref_metadata_2025 huggingface dataset:
Assessment of depression, anxiety and stress among Indian infertile couples in a tertiary health care centre in Bihar
Authors: Singh Kalpana , Shashi Kumari , Rajshee Kumari , Sinha Shivani , Bharti Geetam
Published: January 2020

Background: Infertility rate is on rising trend. It is often associated with a chronic state of stress which may manifest itself in anxiety-related and depressive symptoms. Also, the affected family faces social discrimination, ostracism and stigma which leads to increased anxiety or depression among infertile couples. The motive of this study was to assess the quality of life among infertile couples; to determine the relationship between various domains of quality of life of infertile couples i.e. emotional, mind/body, relational, social, environmental and tolerability and to determine the association of levels of quality of life of infertile couples with the selected variables visiting  IGIMS.Methods: This was a cross-sectional based study; carried out in the department of reproductive medicine, IGIMS, Patna, Bihar for one-year duration (January 2017 to December 2017), on 122 infertile patients attending outpatient department for treatment. Data was collected by using self-administered questionnaire i.e. Ferti QoL questionnaire and HADS.Results: Among all these 96 cases was found to be suffering from primary infertility and 26 cases from secondary infertility. In primary infertile patient social domain was the most affected domain having the greatest impact on their quality of life. In secondary infertile patients the tolerability domain was the most affected domain having the greatest impact on their quality of life. The total fertility quality of life score in primary infertility patients showed a lesser quality of life (55.41) than secondary infertility patients (66.29).Conclusions: This study points at the necessity of specific psychological interventions, presently absent from the public healthcare routine, for women struggling with infertility, to help them manage potential mental health problems and meet their reproductive goals.
A clinical study of ectopic pregnancy at a tertiary care centre in Telangana, India
Authors: Samantaray Subha Ranjan , Mohapatra Ipsita , Vivekanada Achanta
Published: January 2020

Background: Ectopic pregnancy (EP) is a life-threatening obstetrics emergency in early trimester, associated with a high morbidity and mortality if not timely intervened.  High index of clinical suspicion is required for early diagnosis, specifically in women presenting with amenorrhoea, pain abdomen and vaginal bleeding. Aim of this study is to determine the incidence, risk factors, clinical presentation, management and outcome of ectopic pregnancy.Methods: This retrospective observational study was conducted in the department of obstetrics and gynaecology, at Prathima institute of medical sciences, Telangana from July 2012 to June 2019, for a period of 7 years. A total of 53 cases of ectopic pregnancy were analyzed for parameters like age, gravidity, gestational age, risk factors, clinical presentation, management and morbidity.Results: Incidence of ectopic pregnancy was 5.3 per thousand deliveries. Majority of cases were in age group of 20 to 25 years (52.8%) and were gravida 3 and above (68%). The commonest risk factors identified were history of previous pelvic surgeries (37.7%) followed by history of abortion (18.8%). Commonest symptoms were abdominal pain (90.6%), amenorrhoea (75.5%) and vaginal bleeding (47.2%). Only 41.5 % of cases had triad of symptoms. Fallopian tube (92.4%), specifically ampulla (62.3%) was the most frequent site affected. About 73.6% cases presented with ruptured tube. Surgery (94.3%) was the mainstay of therapy.Conclusions: ectopic pregnancy is a life-threatening emergency, early diagnosis and treatment will improve the prognosis.
Cytological and cultural evaluation of abnormal vaginal discharge in pregnancy and its co-relation with maternal and neonatal outcome
Authors: Khairnar Vaibhav Suresh , Waikar Manjushri Ravi
Published: January 2020

Background: Pregnancy represents a risk factor in the occurrence of vaginal infection. This study was undertaken to define the persistence of vaginal flora in 280 pregnant women at 14 to 34 weeks' gestation and to evaluate the role of cytology in diagnosis of vaginal infections. It aims to study the maternal and neonatal outcome in pregnancy with vaginal discharge.Methods: High vaginal swab samples and data on epidemiological characteristics were collected from 280 pregnant women between 14-34 weeks with complaints of abnormal vaginal discharge at booking clinic of Indira Gandhi Government Medical College, Nagpur. Vaginal swab was collected and sent to laboratory for further investigation to establish etiological diagnosis. After diagnosis by vaginal swab report, subjects were treated with the specific treatment to individual infection. Subjects were followed up during antenatal period for complications. A birth weight of delivered baby was noted. The data was analysed using software Graph Pad in stat 3.Results: The incidence of abnormal vaginal discharge in pregnancy was 23.9% in one year. The frequency of abnormal discharge was 53% among those aged 20-24 years (97/183), 49.2% in primigravida (65/132). Pain in lower abdomen and back was the most common symptoms i.e. 88.19% in Cases, while 17.36% had vulval pruritus and 14.58% had dysuria.Conclusions: This study recommend that women complaining of vaginal discharge in pregnancy should be evaluated for infections. this study supports CDC-P recommendation as all women who have symptomatic vaginitis, should be treated regardless of pregnancy status.
Successful maternal and fetal outcome in a patient with chronic myeloid leukemia on chemotherapy
Authors: Jaiswal Nishtha , Khullar Harsha , Mediratta Geeta , Garg Sharmistha
Published: January 2020

Chronic myeloid leukemia (CML) is a myeloproliferative-neoplasm accounting for 15% of adult leukemias. Management of leukemia in pregnancy and effect of anti-neoplastic agents on pregnancy outcomes is not well investigated. Management of pregnancy in CML is complicated by the fact that drug used in its treatment i.e. imatinib can lead to teratogenicity in fetus, whereas withholding the drug may lead to relapse of disease. However, pregnancy itself does not alter course of CML. A 19-year-old female, was diagnosed with CML at 15 years of age. She was positive for Philadelphia chromosome. She was on imatinib and had achieved clinical, hematologic and molecular remission. Patient was on regular follow-up till 18 years of age. 45 months post diagnosis she presented with 8 weeks amenorrhoea. Ultrasound (USG) done at 5 weeks gestation showed a single live intrauterine fetus. She took imatinib during this period of organogenesis, so she was advised medical termination of pregnancy (MTP) by treating oncologist. However, patient denied MTP, so her imatinib was stopped and pregnancy continued. The quantitative Bcr/Abl PCR transcript levels at 16, 20 and 28 weeks of gestation were not detectable. The patient did not develop any symptoms or signs suggestive of CML and total leucocyte count remained normal throughout pregnancy. Patient went into preterm-labor at 36 weeks gestation and delivered a healthy male baby weighing 3.1 kg. The baby was well and had a normal examination. USG abdomen of baby was also normal. CML in pregnancy is rare and imatinib is the drug of choice with which long term survival is possible. Imatinib in large case series has been known to be associated with adverse fetal outcomes although evidence to the contrary also exists. Further studies are needed to draw a conclusion on this debatable issue.
Splenic vessel bleeding in puerperium: a rare maternal near miss case
Authors: Parashar Meetali , Mehta Meena
Published: January 2020

Splenic rupture is a very rare entity during pregnancy and puerperium. It has a very high maternal mortality if not diagnosed and managed in time. Here we are presenting a very rare case of splenic haemorrhage on day 5 lower segment caeserian section which was diagnosed and managed at RIMS, Ranchi, Jharkhand, India.
Unicornuate uterus with functional non communicating rudimentary horn: a refractory cause of dysmenorrhea
Authors: Agarwal Manju , Soni Rakhee , Verma Madhureema
Published: January 2020

Mullerian duct anomalies are rare. Unicornuate uterus with a non-communicating rudimentary horn is a rare type of mullerian duct anomaly which occurs due to defective fusion of malformed duct with contralateral duct. The incidence is approximately 1:100000. Patient usually remain asymptomatic due to the absence of functional endometrium in most of the cases. If the rudimentary uterine horn has an endometrium lined uterine cavity and doesn’t communicate externally then the signs and symptoms of obstructed menstruation appears, as soon as menarche begins. It will be associated with severe dysmennorhoea and hematometra. Other complications may be abdominal lump, chronic pelvic pain, infertility, endometriosis, adenomyosis and ectopic pregnancy in rudimentary horn. Authors are presenting a case of refractory dysmenorrhea with lump abdomen in a patient with unicornuate uterus with functional non communicating horn. In a patient with refractory dysmenorrhea mullerian duct anomaly should be kept as differential diagnosis.
Probiotics for woman’s health focus on urogenital infections and reproductive outcomes
Authors: Shah Phagun , Kumar Pratap , Gupta Mukesh , Gadam Mohan , Ganla Kedar , Kumar Priti , Satija Roshi , Kale Ashish , Chandra Sunita
Published: January 2020

Depletion in vaginal Lactobacilli colonization is associated with poor urogenital health and adverse pregnancy outcomes. Probiotic supplements containing lactobacilli, when administered in adequate amounts, increased vaginal and gut colonization of Lactobacilli, reduced the incidence of bacterial vaginosis and other urogenital infections. Probiotic Lactobacilli reduced preterm births and improved fertility rates in women following in vitro fertilization. Probiotics may also improve implantation rate and live-birth rate in women undergoing IVF. The purpose of this review was to critically analyse the available literature for synthesizing evidence on the use of probiotics and its effect on urogenital and reproductive health in women.
Effect of supervision and education on community health workers performance in the field of primary health care
Authors: Hasani Ziabari Seyede Sakine , Shakerian Sareh
Published: January 2020

Background: Effective supervision strategies help to address the challenges unique to community health workers (CHWs) or Behvarz and improve poor practices. Current research is comparing situation of two supervisors group on performance of CHWs in Lahijan city.Methods: This study was done through a quasi-experimental method in which with census it was considered through pre and post-test after education, then the statistical society was divided through systematic random sampling method and was supervised by two supervisor groups (health care providers and headquarters experts) and their situation were compared using the standard performance checklist in 10 primary healthcare fields for a four month period.Results: Education section showed that 120 CHWs of statistical society, 56 CHWs of capability (in pre-test) answered 70% of questions correctly and in post-test 83 CHWs have answered to 70% of questions correctly and totally it shows 34% of enhancement. Result of in performance section showed that 63% CHWs under supervision of health care providers could have performance higher than 70% in 10 fields. Also result showed that 73% CHWs supervised by headquarter experts could have performance higher than 70% in 10 fields.Conclusions: The effect of the education and supervision on the performance increased although with little difference in the two groups of observers. It can be concluded that the only field that is fully specialized after the implementation of Health Reform Plan is the field of pregnant mothers who provide services to this highly specialized group through midwives.
Study causes of chronic energy deficiency of pregnant in the rural areas
Authors: Wiyono Sugeng , Burhani Annas , Harjatmo Titus Priyo , Ngadiarti Iskari , Prayitno Nanang , . Muntikah , Purbaningrum Ratih Putrbanungtyas , . Westa , Erowati Dewi , Fahira Farha
Published: January 2020

Background: Chronic energy deficiency (CED) is one of the malnutrition problems that often occurs in pregnant, caused by lack of energy in a long period of time. One of the effects of pregnant suffering from CED is to increase the risk of maternal and short baby mortality.Method: The study was conducted in 8 villages of Kemranjen Subdistrict, Banyumas, Central Java, Indonesia in 2019. A cross sectional research design with population is that has pregnant. A sample of 130 pregnant was taken incidentally, with inclusion criteria that be able to do interviews and anthropometric measurements, while as the exclusion criterion was that pregnant were suffering from illness that could not be measured.Results: Most of the age was over 30 years and 9.2% suffered from CED. Nutrient intake is mostly less than 80.0% of the nutrition adequacy rate (RDA). The average intake of macro nutrients is 28.05%, the average micronutrient intake is 27.70%. Most graduated were from high school, worked as housewives, consumed supplements, additional food, and added blood tablets and drank milk, suffered from upper respiratory infections (ARI), high blood pressure, and diabetes mellitus, did not get complete immunizations.Conclusion: There were no significant differences in CED based on energy intake (p=1.00), protein intake (p=1.00), fat intake (p=0.179) and carbohydrate intake (p=0.460),  work status (p=0.216) and education (p=0.553) and consuming additional food (p=0.225).
Risk prediction of cardiovascular diseases and comparison of two prediction models
Authors: Nsanzabera Charles , Sagwe Daniel Nyamongo , Ndengo Marcel
Published: January 2020

Background: Cardiovascular diseases (CVD) are the world leading causes of death in non-communicable diseases. The aim of this study is to predict cardiovascular risk and compare two prediction models.Methods: This cross-sectional study involved 440 sample size of beverage industrial participants. The 10-year prediction was processed by World Health Organization/International Society of Hypertension (WHO/ISH) score chart and Framingham general risk score. WHO stepwise questionnaire and biomedical forms was used. Data was collected and analyzed by SPSS 16.0 version.Results: The overall CVD low risk prediction (<10%) by Framingham general risk score (FGRS) and WHO/ISH score chart was 74.5%, 95.4%, respectively while the CVD elevated risk (≥10%) was 25.5%, 4.6%, respectively. Gender CVD risk (≥10%) was 16.1% of male versus 9.3% of female by FGRS while 2.7% of male versus 1.5% of female classified by WHO/ISH. CVD risk increases in both of the models with age but very much in FGRS. 8.4% of employees versus 5.2% of spouses was classified as having the risk of 10-20% by FGRS while WHO/ISH classified 2.5% of employees and 0.9% of spouses as having the risk of 10-20%. FGRS classified 11.7% of all participant as having the risk above 20% while WHO/ISH classified only 1% as having the risk above 20%. Two model’s kappa agreement level was fair or minimal interrater reliability with 0.25 with p value <0.001 and the correlated receiver operating characteristic curve (ROC) curve of FGRS and WHO/ISH of 0.887 area under the curve (AUC), 0.847AUC all with a p value <0.001, respectively.Conclusions: FGRS predicted more risk in participants than WHO/ISH and was with minimal kappa agreement.
Prevalence of hypertension amongst employee’s state insurance beneficiaries of four districts in Haryana
Authors: Narang Sangeeta , Singh Mitasha , Yada Jyoti , Dixit Shivam , Singh Narendra
Published: January 2020

Background: Raised blood pressure (hypertension) caused an estimated 9.4 million deaths in 2010. 22% of adults aged 18 years and over around the world had raised blood pressure in 2014 In India prevalence of Hypertension is 22.4% (13.5% in Haryana, district Faridabad) according to National Family Health Survey 2015-2016. A number of studies have estimated the prevalence of hypertension in general population in our country but data regarding the prevalence of hypertension in industrial workers has not been documented in the recent past. The objectives of the study were to calculate the prevalence of hypertension and its associated risk factors in employee’s state insurance (ESI) beneficiaries in four districts in Haryana.Methods: Cross-sectional study was done on 365 ESI beneficiaries working in industries in four districts of Haryana. Predesigned structured self-administered questionnaire was used for interview. Blood pressure measurement and all the anthropometric measurements were done by the following standardized technique.Results: The overall prevalence of hypertension was found to be 17.26%. The severity of hypertension increased significantly with age (p=0.006). Overweight and obese participants had higher proportion of hypertensive, however, history of shift duty, drug abuse, tobacco and alcohol intake did not show a significant trend of severity of HTN.Conclusions: From the results of the present study, it can be concluded that there are a large number of undiagnosed cases of hypertension amongst employee’s state insurance corporation (ESIC) beneficiaries. It is, therefore recommended that health check-up and awareness camps should be conducted on regular basis for early detection and timely treatment of hypertension.
Unmet needs for family planning and its socio-demographic correlates among women in the reproductive age group in central rural India
Authors: Pawar Ramesh Devidas , Solanke Shital Pratapsing
Published: January 2020

Background: Unmet need is the discrepancy between reproductive intentions and birth control practices. If the unmet needs remained neglected it leads to population explosion which is one of the greatest threats to India’s economic, social and political development.  A community-based study was carried out in rural areas with the objective to find the prevalence of unmet need for family planning and its socio-demographic determinants among married women of reproductive age.Methods: A community based cross sectional study was conducted between January to June 2019. After calculation of sample size 670 participants were selected by simple random sampling method.  Predesign and semi structured Performa was used for data collection. Data was collected and analyse using Epi Info 7.Results: Unmet needs of family planning among the study subject was 31.19% (57.58% for the spacer and 42.42% for limiter). It was significantly higher among the Muslim (66.67%) and Boudh (40.38) religion. It was higher among Illiterate (40.82%), women residing in joint families (72.16%). Unmet need of family planning was significantly associated with age of women, religion, educational status of women and their husbands, occupation, type of family, no of children the women have and age at marriage.Conclusions: Unmet needs among married women in the reproductive age group was still high and was significantly associated with age of women, religion, educational status of women as well as their husband, occupation, type of family, number of children the women had and age at marriage.
Clinical profile and outcome of patients with indeterminate acute liver failure
Authors: Nabi Tauseef , Rafiq Nadeema
Published: January 2020

Background: Acute liver failure (ALF) is a rare medical emergency and devastating clinical syndrome associated with high mortality. Indeterminate ALF still forms a significant number of cases in India as well in the world. We aimed to determine the clinical profile and outcome of patients with indeterminate ALF.Methods: A total of 30 patients with a diagnosis of Indeterminate ALF were included in the study. The variables evaluated were demographic, signs and symptoms, biochemical parameters, severity of liver injury, outcome, complications and duration of hospital stay.Results: Overall mortality was 18 (60%). Majority of the patients were females (56.7%). Majority of patients (60%) had grade III and IV encephalopathy at the time of admission. The mean age in Survived group was 30.6±11.6 years and in Died group was 42.6±10.2 years (p=0.005). INR, bilirubin AST, ALT and creatinine were significantly higher in Died group than Survived group. Mean grade of coma was significantly higher in Died group than Survived group (p=0.010). MELD Score was significantly higher in Died group 35.8±6.7 than Survived group 27.5±5.8 (P = 0.001). Sepsis and renal failure occurred more frequently in Died group. Duration of hospital stay was also significantly more in Died group versus Survived group (p=0.003).Conclusions: Indeterminate ALF disproportionately affected young females. Mortality was as high as 60%. The marked difference in spontaneous survival can be explained by the severity of hepatic dysfunction on admission and more frequent complications.
Screening for diabetes mellitus among the rural population applying Indian diabetes risk score in field practice areas of Kamineni Academy of Medical Sciences and Research Centre
Authors: M. N. Rama Krishna , B. Manoj Aravind , Singh C. Sunil Pal , Reddy P. Narasimha
Published: January 2020

Background: Globally an estimated 422 million adults are living with Diabetes as per WHO data 2014, and 85 to 90% cases are type 2 diabetes. Maximum number of people with diabetes mellitus are in the age group of 40 to 59 yrs. Among them 50% are undiagnosed. Sedentary lifestyle, diet, dietary fiber, mal-nutrition, some chemical agents, stress, alcohol, viral infections, etc., are some environmental risk factors.Methods: A cross sectional, community based study. Details of the study subjects were recorded using structured predesigned and pretested questionnaire. All the data collected was entered and analyzed with MS Excel software 2007 and Epi info 3.5.3. All tests were considered significant at p <0.05 level.Results: In our study, majority of population participated in the screening camp are between 30 to 35 years of age, Female (53.2%) participants were more. We found that 38 (24.1%) persons were found to be in pre-diabetic stage, 57 (37.3%) are having high risk of getting diabetes.Conclusions: There is significant relationship between smoking, alcohol consumption and sedentary lifestyle (p<0.05) to the risk of diabetes as per Indian diabetes risk score.
A cross sectional study to ascertain various causes of neonatal mortality using verbal autopsy in Etawah district
Authors: Ali Nawazish , Jain Pankaj Kumar , Shukla Sushil Kumar , Srivastava Dhiraj Kumar , Chaurasiya Shailendra Kumar , Mathew Debora Jose
Published: January 2020

Background: Neonatal death is defined as no. of deaths during the first 28 completed days of life per 1000 live births in a given year or period.  Around 2.6 million deaths or roughly 46% of all under five deaths had occurred during this period in 2016 which means that 7000 newborn deaths occur each day. Most of the neonatal deaths occur on the first day and week accounting to about 1 million dying on the 1st day. Objective of this study was to ascertain various causes of neonatal mortality using verbal autopsy in Etawah district.Methods: The present study was a retrospective cross-sectional study carried out for a period of 1 year (July 17 to June 2018) using WHO verbal autopsy questionnaire by finding out the study subjects from medical information system of UPUMS, Saifai and district hospital, Etawah. A total of 89 neonatal deaths were found out of which 87 were interviewed by going to their residences to get the relevant information regarding the causes of deaths.Results: Most common cause of neonatal mortality came out to be low birth weight with prematurity 44 of 87 (50.6%), followed by birth asphyxia 23 of 87 (26.4%) and sepsis 8 of 87 (9.2%).Conclusions: Effective interventions should be incorporated into policy decisions to reduce neonatal mortality due to these causes.
Study of socio-demographic and treatment profile and other epidemiological correlates of clients attending revised national tuberculosis control programme clinic in a tertiary hospital of West Bengal, India
Authors: Kundu Subha Sankha , Sikder Rajib , Dey Rituraj , Majumdar Kunal Kanti , Joardar Gautam
Published: January 2020

Background: Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis bacteria spread by droplet infection.According to global TB report 2017, there were approximately 28 lakhs cases of TB in India accounting a quarter of the world TB cases. Today, it is the fastest-expanding and the largest program in the world in terms of patients initiated on treatment and the second largest in terms of population coverage. The objective of this study is to assess the socio-demographic profile of the patients attending revised national TB control programme (RNTCP) clinic, to determine the nature of disease, its co-morbidities, seasonal variability and treatment profile of the patients attending the RNTCP clinic during this study period.Methods: This was a retrospective record-based study conducted in RNTCP clinic of KPC Medical College and Hospital, Kolkata. Details of all the 684 patients who were enrolled under RNTCP from the year 2014 to 2018 were collected from RNTCP records. Data was analyzed using suitable software.Results: 684 cases were registered and treated under directly observed treatment, short-course (DOTS) during the study period with 41% completing treatment. 84.3% were new TB cases. 23.61% were sputum smear positive. Males (67.25%) contributed to more in cases. Maximum patients visited during March to June. 74.87% of the total patients were diagnosed with pulmonary TB. Pleural effusion was the commonest form of extrapulmonary TB (42.75%).Conclusions: The number of TB cases showed a decreasing trend over the years. Males contributed to a greater number of cases with majority being contributed by the age group 21-30 years.
Health and wellness centers: a paradigm shift in health care system of India?
Authors: Solanki Hariom K. , Rath Rama Shankar , Silan Vijay , Singh Satya V.
Published: January 2020

An ambitious attempt to achieve the goal of universal ‘comprehensive’ primary care through health and wellness centres under the Ayushmann Bharat Scheme (ABS) has been made by the Ministry of Health and Family Welfare, Government of India. The scheme has widened the package of services available to beneficiaries and it also envisages continuum of care. However, there are pre-existing weaknesses in the three tired public health system in India which may threaten the success of this scheme. In this article we describe and analyze the newer services or initiatives at the health and wellness centres under the ABS. We also attempt to identify the Strengths, weaknesses, threats and opportunities associated with this initiative.
Process of forming mirror-shaped relief plates of folded structure
Authors: Khaliulin V. I. , Gimadiev R. Sh. , Markovtsev V. A. , Levshonkov N. V.
Published: January 2020

We present a process flow sheet that allows dividing the process of shaping of folded structures into several stages. The formation of the relief is achieved by inverting individual sections of the trapezoidal corrugation to give them a mirror-reflected shape. The process is characterized by narrow zones of bending deformations along the lines of the structure marking and by warping of faces without drawing. The field shaper layout and the relationships for calculating geometric and process parameters are presented.
Ponadkonfesyjny model działalności śląskich organmistrzów w XIX i w początkach XX wieku na przykładzie działalności Moritza Roberta Müllera oraz Carla Volkmanna i Ernsta Kurzera
Authors: Koenig Franciszek
Published: January 2020

Śląsk od czasów reformacji w XVI w. był i pozostał terenem współistnienia wielu wyznań chrześcijańskich. W przeszłości różnice te rodziły różnego rodzaju napięcia, a nawet konflikty. Jednak w wielu wymiarach życia społecznego, gospodarczego, a także kulturowego, istniała „praktyczna ekumenia”. Jej istotą był fakt ponadkonfesyjnego działania, a więc współpraca bez względu na wyznanie. Tak było m.in. na polu budownictwa organowego, które w tradycji Dolnego i Górnego Śląska stanowi niezwykłe bogactwo kulturowe.

Niniejszy artykuł prezentuje przykłady takiego sposobu działania z okresu XIX i początku XX w. Spośród dolnośląskich organmistrzów został przykładowo wybrany wrocławski budowniczy Moritz Robert Müller, a spośród grona górnośląskich organmistrzów jako przykłady posłużyli dwaj współpracujący ze sobą gliwiccy organmistrzowie: Carl Volkmann oraz Ernst Kurzer. Wszyscy oni budowali organy zarówno w kościołach katolickich, jak i ewangelickich. Zastosowany przez nich model pracy pokazuje, że w ówczesnym środowisku, bardzo wyczulonym na sprawy muzyczne, nie liczyła się kwestia wyznania budowniczego, a jedynie jego kompetencje.
Церковно-співочі ініціятиви Василіянських монастирів
Authors: Yasynovskyi Yurij
Published: January 2020

Działalność w zakresie śpiewu kościelnego w monasterach bazyliańskich

Autor artykułu podkreśla rolę, jaką odegrały bazyliańskie monastery w rozwoju śpiewu kościelnego oraz muzyki instrumentalnej. W XVII w., na terenie Ukrainy i Białorusi, wspierały one nie tylko tradycyjny śpiew liturgiczny, ale i nowe rozwiązania, co potwierdzał m.in. Jozafat Kuncewicz OSBM. Nie bez znaczenia był tutaj również wpływ kultury zachodniej, oddziałującej na Kościoły wschodnie. Monastery te stały się ważnym ośrodkiem rozwoju późnobizantyjskiej kultury śpiewu kościelnego, rozpowszechniając styl śpiewu kalofonicznego także na terenach rosyjskich (głównie moskiewskich), bułgarskich i mołdawskich. Oprócz monodycznego śpiewu melizmatycznego w klasztorach praktykowano śpiew partesny i chóralny (monaster w Żyrowiczach), działali tam liczni śpiewacy i kompozytorzy (np. w Ławrze Peczerskiej w Kijowie), zaś podczas świąt wprowadzano nawet muzykę instrumentalną (jak to miało miejsce w Ławrze Uniowskiej, gdzie przebywał wówczas Atanazy Szeptycki).
Z dziejów muzyki w kościele pw. św. Mikołaja w Nowym Waliszowie na Ziemi Kłodzkiej
Authors: Prasał Andrzej
Published: January 2020

Początki kultury muzycznej Nowego Waliszowa związane są z tamtejszą świątynią pw. św. Mikołaja. Już w 1699 r. wyposażono ją w 7-głosowy pozytyw. Obecne organy zostały wybudowane w 1912 r. przez firmę Schlag & Söhne ze Świdnicy. Instrument typu multiplex o pneumatycznej trakturze rejestrów i gry posiada 15 głosów, w tym dziewięć realnych. Niewielka parafia dysponowała także zespołem wokalno-instrumentalnym, który nie tylko dbał o liturgię, ale także organizował koncerty. W 1930 r. liczył 31 chórzystów i 16 instrumentalistów. Zespół prowadzili miejscowi nauczyciele, którzy byli jednocześnie organistami. Cennych informacji o repertuarze chóru dostarcza inwentarz muzykaliów z 1939 r. obejmujący m.in.: 69 mszy, 28 zbiorów graduałów, 21 zbiorów ofertoriów, 15 zbiorów hymnów, 14 litanii oraz dużą liczbę pieśni kościelnych. Na jego podstawie można stwierdzić, że zarówno pod względem doboru utworów, jak i wykonawstwa repertuar ten nie tylko dorównywał, ale niejednokrotnie przewyższał praktykę muzyczną innych wiejskich świątyń ziemi kłodzkiej.
Działalność muzyczna Leona Kubicy na Śląsku Opolskim
Authors: Godek Andrzej Edward
Published: January 2020

Niniejszy artykuł poświęcony jest życiu i muzycznej działalności Leona Kubicy, cenionego w okresie międzywojennym muzyka kościelnego ze Śląska Opolskiego. Był on uczniem Tomasza Cieplika, następnie zaś kontynuował naukę w Szkole Muzyki Religijnej w Ratyzbonie. W tym też czasie stał się znanym i cenionym kompozytorem. Jego dzieła wykonywane były przez liczne polskie chóry na terenie Śląska Opolskiego. Również sam Kubica był czynnym działaczem polskiego środowiska w Rzeszy Niemieckiej i dyrygował szeregiem zespołów. Zaangażowanie to przyczyniło się do jego początkowego uwięzienia w obozie koncentracyjnym w Buchenwaldzie, a następnie wysłania go na front wschodni, gdzie zginął.

Najnowsze badania oparte na prasie, spuściźnie kompozytora przechowywanej w zbiorach rodziny oraz na dokumentach z archiwów państwowych pozwoliły na przedstawienie nowych informacji do biografii Leona Kubicy, a także jego działalności muzycznej w środowisku polskim na terenie Śląska Opolskiego oraz listy wykonań jego dzieł do 1939 r. W ostatniej części rozważań przedstawiona została analiza Mszy polskiej, najbardziej znanej z jego kompozycji.
Misterium Objawienia Pańskiego jako treść homilii
Authors: Dyk Stanisław
Published: January 2020

Niniejsze opracowanie, na podstawie analizy źródeł przepowiadania, ukazuje zarys treści homilii na uroczystość Objawienia Pańskiego. Głównym tematem tej celebracji jest Chrystus, który w wydarzeniu pokłonu Mędrców objawia chwałę Boga wszystkim narodom. Wyraźnie podkreślony jest uniwersalizm zbawienia. Chrystus jawi się jako osobowe „miejsce”, w którym każdy człowiek znaleźć może spełnienie swych duchowych dążeń. W celebracji mamy także objawienie Kościoła, który ukazany jest jako wspólnota nosząca w sobie pokój Boga, zgromadzenie ludzi pojednanych ze sobą oraz otwartych na tych, którzy szczerze szukają zbawienia. W treści homilii należy wskazać na uobecnienie tego zbawczego wydarzenia w celebracji liturgicznej. Znakami, które pomogą wiernym w rozpoznaniu tego misterium w liturgii, są chleb i wino, które przemienione w Ciało i Krew Chrystusa stają się źródłem jedności wszystkich narodów; postawa klęcząca jako wyraz adoracji Zbawiciela; światło jako objawienie Bożej miłości i chwały. Uczestnicy tej celebracji winni mieć także właściwą duchową dyspozycję, która odzwierciedli drogę Mędrców odbytą w poszukiwaniu Mesjasza. Duchowa wędrówka wiernych w czasie celebracji liturgicznej znajduje swoją kontynuację w życiu wierzących poprzez postawę ciągłego poszukiwania i kontemplowania Boga w „ubóstwie” codziennego życia, w ludziach ubogich, w pięknie natury, na drogach rozumu, w Kościele, który jest stróżem Bożego Objawienia. Wierni wezwani są także do duchowego nawrócenia, aby przez nowość swojego życia stali się „światłem”, które pociągnie do Boga innych ludzi.
The Holy Spirit and the Christian Life in the Neoevangelical Preaching
Authors: Krauze Łukasz
Published: January 2020

Duch Święty a życie chrześcijanina w przepowiadaniu neoewangelikalnym

Teologia neoewangelikalna, osadzona w kulturze Stanów Zjednoczonych, jest pewnego rodzaju kompromisem, w świecie protestanckim, pomiędzy myślą fundamentalną a liberalną. Stąd wydaje się najbliższa w swych założeniach teologii Kościoła katolickiego. W związku z tym zasadne jest zbadanie, co mówi o roli Ducha Świętego w kształtowaniu chrześcijańskiego życia. Niniejszy artykuł ukazuje, w oparciu o kaznodziejstwo Billego Grahama, cztery aktywności Ducha Świętego w życiu chrześcijanina, wyróżniane przez teologię neoewangelikalną: poucza o grzechu, daje nowe życie, pomaga wybrać Boga, pozwala zrozumieć Biblię. Każda z nich została opatrzona komentarzem z perspektywy teologii katolickiej.
THE IMPACTS OF ONLINE SOCIAL NETWORKS ON ACCOMMODATION PREFERENCES: THE CASE OF TURKEY
Authors: TÜRKCAN Burcu
Published: January 2020

Online social networks directly influence the sectors
by shaping the preferences of individuals. In this respect, it is not a
coincidence that social media is seen as a digital marketing tool today. In
this context, this study aims to examine the impacts of online social networks
on accommodation preferences of tourists with a country case analysis. In
accordance with this purpose, a questionnaire has been conducted with a large
sample of 497 respondents. Data has been analysed using the frequency
distributions, One-Way ANOVA Test, Tamhane t Test and Pearson Correlation
Analysis. The main findings indicate that Turkish tourists use online social
networks frequently, they intend to share their experiences and also there are
differences in research and sharing attitudes as to education level. This study
intends to make a contribution to the related literature by providing detailed
evidences with a large sample from Turkey.
TÜRKİYE’DE KARBON EMİSYONLARI, YENİLENEBİLİR ENERJİ VE EKONOMİK BÜYÜME
Authors: OZDEMİR Bilge Kağan , KOÇ Kübra
Published: January 2020

Bu çalışmanın amacı, Çevresel Kuznets Eğrisi hipotezi (EKC)’nin geçerliliğini Türkiye örneğinde test etmektir. Bu amaç doğrultusunda, kişi başına CO2 emisyonları, kişi başına reel GSYH, kişi başına enerji kullanımı, kişi başına yenilenebilir enerji kullanımı ve ticari dışa açıklık değişkenleri ile kübik formda bir model kurulmuştur. ARDL Sınır Testi ile uzun dönem denge ilişkisi tespit edilmiştir. Ampirik bulgulara göre kişi başına CO2 emisyonları ile kişi başına gelir arasında N-şeklinde kübik polinominal ilişki tespit edilmiştir. Uzun dönem katsayı tahminlerine göre bağımlı değişken olan kişi başına CO2 emisyonu üzerinde tamamı istatistiksel anlamlılığa sahip olmak üzere, enerji kullanımının pozitif, yenilenebilir enerjinin negatif, ticari dışa açıklığın da pozitif etkisinin olduğu tespit edilmiştir. Ampirik bulgulara göre, Türkiye'nin enerji matrisini yenilenebilir enerji lehine yeniden şekillendirmek son derece yararlı olacaktır.
The content of N-acetylneuraminic acid in glycoproteins of erythrocyte membranes in Morris hepatoma 5123 bearing rats.
Authors: Batko J , Karoń H
Published: January 2020

Changes in the content of N-acetylneuraminic acid in rat erythrocyte membranes at different stages of experimental tumour (Morris hepatoma 5123) development were examined. Its content was lowered on the 30th and 40th day after transplantation of the tumour cells, as compared to the results for normal healthy rats. As a result of the tumour growth, the content of N-acetylgalactosamine, galactose and mannose in rat erythrocyte membranes became lowered, whereas that of glucose remained unchanged. The content of fucose was raised at early stage of tumour growth, and remained at this high level till the 40th day of experiment.
The epidermal growth factor-like domain from tissue plasminogen activator. Cloning in E. coli, purification and ESR studies of its interaction with human blood platelets.
Authors: Pietrucha T , Stec W J , Okruszek A , Uznański B , Koziołkiewicz M , Wilk A , Płucienniczak A , Swiatkowska M , Cierniewski C S
Published: January 2020

To examine whether the epidermal growth factor (EGF)-like domain Pro47-Asp87 is involved in the interaction of tissue plasminogen activator (t-PA) with platelets, we have expressed this domain in E. coli. The peptide fragment was produced from a plasmid expression vector as a fusion protein with beta-galactosidase Met1-Val444 at high yield in eight clones of E. coli. The fusion protein was purified and subjected to mild acid hydrolysis with formic acid, then the peptide Pro47-Asp87, identified by immunoblotting using specific antibodies to t-PA, was isolated by HPLC. After incubation with blood platelets spin labelled with 16-doxylstearic acid or 5-doxylstearic acid, the Pro47-Asp87 peptide fragment reduced fluidity of the membrane lipid bilayer to the same extent as did intact t-PA as indicated by ESR measurements. Our data suggest that the EGF-like domain of t-PA can directly interact with blood platelets and thus it seems to contain those sites of the t-PA molecule that bind the platelet membrane components.
Evidence for plant ribosomal 5S RNA involvement in elongation of polypeptide chain biosynthesis.
Authors: Shaikhin S , Sobkiewicz A , Barciszewski J , Twardowski T
Published: January 2020

A series of short oligo-DNA probes (8-10-mers) complementary to various regions of the plant ribosomal 5S ribonucleic acid (5S rRNA) have been synthesized. The results of their hybridization to free 5S rRNA and to ribosomes pointed to the availability of nucleotides in loop "C" for complexation. We found a correlation between hybridization of selected oligonucleotides and their inhibitory effect on enzymatic binding of Phe-tRNA and poly(Phe) synthesis on wheat germ 80S ribosomes. Evidence was obtained for involvement of 5S rRNA in the elongation of polypeptide chain during protein biosynthesis. 5S rRNA seems to play a critical role in protein biosynthesis, probably through causing conformational changes of loop C.
Characterization of the mitochondrial DNA polymerase from Saccharomyces cerevisiae.
Authors: Sen S , Mukhopadhyay S , Wetzel J , Biswas T K
Published: January 2020

The mitochondrial DNA (mtDNA) polymerase was isolated from a protease-deficient yeast strain (PY2), and purified about 3000 fold by a column chromatography on phosphocellulose, heparin-agarose, and single-stranded DNA cellulose. The purified polymerase was characterized with respect to optimal nucleotide concentrations, template-primer specificity and sensitivity to some inhibitors. These results were compared with the nuclear DNA polymerase I activity. Both polymerases showed similar requirement of deoxynucleotide concentrations (Km < 1 microM), and highest activity with poly(dA-dT) template. However, the mtDNA polymerase was more sensitive to ddTTP, EtBr and Mn2+ inhibition in comparison to the nuclear DNA polymerase I. The mtDNA polymerase did not need ATP as an energy source for in vitro DNA synthesis. This mtDNA polymerase preparation also showed 3'-->5' exonuclease activity.
A memória e o autoconhecimento nas vivências ambientais urbanas enquanto proposta educativa
Authors: Hofstatter Lakshmi Juliane Vallim , Oliveira Haydée Torres de
Published: January 2020

Diante do fato da maior parte da população brasileira viver nas cidades, procuramos melhor compreender quais são os caminhos experenciados na infância e vividos por pessoas que possuem vínculos afetivos com áreas verdes urbanas. Trabalhamos individualmente com 9 estudantes universitários, na perspectiva fenomenológica, entrevistando e realizando atividades conjuntamente em lugares eleitos como tendo significado afetivo na cidade de Salvador, BA, o que oportunizou momentos reflexivos de autoconhecimento às pessoas participantes. Percebemos, através de suas memórias, a importância desses lugares no engajamento que essas pessoas têm com e no mundo, pois a convivência desde a infância nos ambientes naturais na cidade influenciou em suas escolhas de vida. Destacamos a importância das áreas verdes urbanas acessíveis à toda população e a possibilidade de trabalhar a memória e o autoconhecimento nas práticas ambientais educativas enquanto forma de revisitar nossos elos ambientais e, também, fortificá-los através de novas vivências.
Forecasting of need in postcardiosurgery hospitalizations on the basis of symptom-syndrome structuring of factors
Authors: Alexeyeva N. P. , Gorlova I. A. , Bondarenko B. B.
Published: January 2020

Background. Study of predictive need in the future hospitalizations still was not carried out though it can be useful for solution of both medical and social-economic issues of health care.

 Objective. Study of a possibility of forecasting of repeated hospitalizations in various terms after cardiac surgery on a set of characteristics of the patients in pre- and postoperative (hospital) periods.

Design and methods. Results of long regular postoperative follow up (in terms up to 12 years) for 114 patients (80 men and 34 women) with the infective endocarditis (IE) after valve replacement of various localizations are analysed. The initial database included 133 factors — demographic, clinical, laboratory and tool characteristics of patients. Frequency and the reasons of hospitalizations, symptoms of disease complications — the prosthesis depended and independent were considered. In order to solve the prognostic problem, there were used a symptom-syndrome approach, providing expansion of the factor space due to the most significant factor combinations and the method of projective classification of patients, which provides a reduction of the degree in predictive randomness.

Results. Three integrated factors, the most significant for forecasting of repeated hospitalizations are allocated. The first interpreted as “a factor of adequate treatment” included belonging to a male gender, maintaining working capacity and no need in postoperative use of cardiac glycosides (CG); the second one unites such variants as existence of either regular atrial fibrillation or need in implementation of temporary cardiostimulation in patients with HF III–IV (NYHA). The third integrated factor consisted of a combination of aortic valve prosthesis, nonphysical work and need in postsurgery inotrop support. Combination of two and more integrated factors resulted in high probability (the importance of distinction 0.000007) allocations of groups with low and high risk of repeated hospitalizations — 9.5 % (4 of 43 patients) and 58.1 % (18 patients from 31) correspondingly.

Conclusion. The proposed technique can be used for similar purposes in various categories of patients for advance planning of treatment, preventive, social and economic measures.
Effect of sevoflurane on high-frequency brain electrical activity
Authors: Arkhipova N. B. , Aleksandrov M. V.
Published: January 2020

Background. In 30 % of cases with epilepsy, it qualifies as medically intractable and requires surgical treatment. The need for improvement of epilepsy surgery effectiveness demands updating of the preoperative assessment protocols. Intraoperative wide-range electrocorticography is a novel technique for defining resection volume in focal structural epilepsy. Combined analysis of high-frequency and epileptiform activity provides additional information and allows prognosticating of surgery outcome. However, consistent evaluation of intraoperative monitoring results is only possible when general anesthetic effect on brain electrical activity is taken into account.

Objective. This study was aimed at evaluation of anesthetic gas sevoflurane effect on high-frequency brain electrical activity, recorded directly from the cortex or deep brain structures.

Design and methods. Eight patients were included in this study (2 females, 6 males), aged 19 to 47, with a long-term epilepsy (disease duration 15 to 38 years). Prolonged electrocorticographic monitoring was indicated to these patients, combined with eloquent zones mapping in some cases. Patients were implanted with grid electrodes on frontal and temporal cortex, and deep brain Spencer electrodes into the mesial temporal lobe. Wide-range electrocorticography was recorded during slow-wave sleep and intraoperatively under sevoflurane anesthesia. Pathological high-frequency oscillations (pHFOs) rate was counted.

Results. In seven patients pHFOs were recorded extraoperatively. Pathological HFO rate varied between 13 and 30 % (mean — 19 %). Distribution of pHFO did not change due to anesthesia effects. Mean background noise amplitude was significantly decreased intraoperatively (z = 2.45; p = 0.014). This effect facilitated visual marking of pHFOs. There were no trends in comparison between extraoperative and intraoperative pHFO rate.

Conclusion. Well-controlled levels of general anesthesia obtained with sevoflurane (0,9-1,1 MAC) showed minimal effect on high-frequency brain electrical activity. This allows thorough analysis of wide-range electrocorticogiaphy without waking the patient and provides more information about the extension of the epileptogenic zone and its resection rate intraoperatively.