bluuebunny/crossref_metadata_2025 huggingface dataset:
Sickness Presence among Disabled Workers at the University Medical Centre Ljubljana / Prezentizem Med Invalidi V Univerzitetenem Kliničnem Centru Ljubljana
Authors: Škerjanc Alenka , Dodič Fikfak Metoda
Published: October 2014

Objectives. The aim of the article is to investigate the differences in sickness present and non-sickness present in the group of disabled health care professionals.

Methods. Data were gathered from all disabled health care professionals suffering from invalidity of category II or III who were identified in the research among all health care professionals at the University Medical Centre Ljubljana and who were employed there in the period between 1 January 2010 and 31 December 2010. Each employee obtained a questionnaire composed of three standardized international questionnaires.

Results. There were 248 disabled workers of the II. and III. category of invalidity among the participants. Disabled sickness present reported to have more chronic diseases than disabled non-sickness present (OR = 57.0; 95% CI = 24.4-133.2), lower salary when on sick leave (OR = 13.1; 95% CI = 5.7- 30.2) and poor self-rated health (OR = 5.8; 95% CI = 2.7-12.3).

Conclusions. The prerequisite for sickness presence among disabled workers is their chronic bad health. It is also formally recognized with the degree of disability. Economic factors are among the most important to direct disabled workers towards sickness presence. The results indicate that workplaces are not adapted to disabled workers in regard to their limitations.
Sylvester Hadamard matrices revisited
Authors: Mitrouli M.
Published: October 2014

In this work we revisited some properties of Sylvester Hadamard matrices of order 2k. Based onlyon the existence of a base from which any Sylvester Hadamard matrix can be constructed, we prove that theirrows (columns) are closed under addition and that the numbers of sign interchanges along any row (column)give all integers 0, 1, . . . , 2k − 1 in some order. These two properties can be used to check if an Hadamardmatrix is equivalent to a Sylvester Hadamard matrix.
Sunbelt Scholarship and Silos
Authors: Richert Lucas
Published: October 2014

Abstract:

The last five years have witnessed a series of books exploring the post–World War II rise and growth of the American West and South, an area of the United States sometimes called the Sunbelt. The term, coined in1969 by Kevin Phillips, identified a rather amorphous region that was undergoing rapid transformation and was, therefore, vital for long-term Republican electoral success. However, scholars do not universally accept the “Sunbelt Phenomenon,” nor has the concept produced intellectual consensus. Instead, authors are now rethinking previous methodologies about the United States after World War II and reformulating the configuration of social, political, and economic categories of analysis. The Sunbelt concept is now being renegotiated. In recent years, works by Michelle Nickerson and Darren Dochuk; Jeff Roche; Elizabeth Tandy Shermer; and Kim Phillips-Fein and Julian Zelizer have signalled the energy of the debates as well as the evolving literature as a whole. Problematically, as much as this new literature shows expansion, the scholarship also demonstrates a small, though consequential, silo mentality.
Philip Roth’s Mock Lincoln
Authors: McDonald Brian J.
Published: October 2014

Abstract:

This article considers the core political ideas that animate Philip Roth’s McCarthy-era novel I Married a Communist through a critical analysis of the novel’s central character, Ira “Iron Rinn” Ringold. It argues that, with Ira, Roth dramatizes the ambiguity that surrounds both the Lincolnian ideal of individual self-determination and the intractable presence of betrayal in the theory and practice of American liberal democracy.
Detroit Works Long-Term Planning Project: Engagement Strategies for Blending Community and Technical Expertise
Authors: Griffin Toni , Cramer Dan , Powers Megan
Published: October 2014

In January 2013, civic leaders, community stakeholders, and residents came together to release Detroit Future City: 2012 Detroit Strategic Framework Plan, a guiding blueprint for transforming Detroit from its current state of population loss and excessive vacancy into a model for the reinvention of post-industrial American cities. Three years prior, the U.S. Census had reported that the city had lost 24% of its population over the last decade and had experienced a 20% increase in vacant and abandoned property, bringing total vacancy to roughly the size of Manhattan. In addition to physical and economic challenges, Detroiters had also acknowledged significant barriers to effective civic engagement. Foremost among these barriers were a profound sense of immobilization, planning fatigue, and a general perception of cynicism about planning and engagement efforts. These challenges were compounded by historic racial dynamics and tension. This case study elaborates on the comprehensive and innovative civic engagement executed in a citywide planning process called the Detroit Works Project, which took place from late 2010 through late 2012. For the citywide planning process to be successful and sustainable, civic leaders and project funders committed to a planning initiative that would be different from previous efforts, in large part because the “owners” of the process would be diverse and inclusive across all community sectors. The case study, written by three of the key consultants from the project, describes four key civic engagement strategies deployed in the creation of the strategic framework: (1) addressing profound challenges of culture, race, and politics by deliberately building trust; (2) elevating community expertise by fostering a sense of ownership of the process; (3) blending technical and community expertise; and (4) viewing civic engagement as an ongoing two-way conversation rather than a series of large-scale episodic events. This article elaborates on important lessons that other communities might learn from Detroit’s planning initiative in relation to these strategies. It concludes with a brief summary of the results and implications of the civic engagement process.
Performance Degradation Assessment of Rolling Element Bearings Based on an Index Combining SVD and Information Exergy
Authors: Zhang Bin , Zhang Lijun , Xu Jinwu , Wang Pingfeng
Published: October 2014

Performance degradation assessment of rolling element bearings is vital for the reliable and cost-efficient operation and maintenance of rotating machines, especially for the implementation of condition-based maintenance (CBM). For robust degradation assessment of rolling element bearings, uncertainties such as those induced from usage variations or sensor errors must be taken into account. This paper presents an information exergy index for bearing performance degradation assessment that combines singular value decomposition (SVD) and the information exergy method. Information exergy integrates condition monitoring information of multiple instants and multiple sensors, and thus performance degradation assessment uncertainties are reduced and robust degradation assessment results can be obtained using the proposed index. The effectiveness and robustness of the proposed information exergy index are validated through experimental case studies.
Control Strategies to Smooth Short-Term Power Fluctuations in Large Photovoltaic Plants Using Battery Storage Systems
Authors: Marcos Javier , De la Parra Iñigo , García Miguel , Marroyo Luis
Published: October 2014

The variations in irradiance produced by changes in cloud cover can cause rapid fluctuations in the power generated by large photovoltaic (PV) plants. As the PV power share in the grid increases, such fluctuations may adversely affect power quality and reliability. Thus, energy storage systems (ESS) are necessary in order to smooth power fluctuations below the maximum allowable. This article first proposes a new control strategy (step-control), to improve the results in relation to two state-of-the-art strategies, ramp-rate control and moving average. It also presents a method to quantify the storage capacity requirements according to the three different smoothing strategies and for different PV plant sizes. Finally, simulations shows that, although the moving-average (MA) strategy requires the smallest capacity, it presents more losses (2–3 times more) and produces a much higher number of cycles over the ESS (around 10 times more), making it unsuitable with storage technologies as lithium-ion. The step-control shown as a better option in scenery with exigent ramp restrictions (around 2%/min) and distributed generation against the ramp-rate control in all ESS key aspects: 20% less of capacity, up to 30% less of losses and a 40% less of ageing. All the simulations were based on real PV production data, taken every 5 s in the course of one year (2012) from a number of systems with power outputs ranging from 550 kW to 40 MW.
Real-Time Wavelet-Based Coordinated Control of Hybrid Energy Storage Systems for Denoising and Flattening Wind Power Output
Authors: Trung Tran , Ahn Seon-Ju , Choi Joon-Ho , Go Seok-Il , Nam Soon-Ryul
Published: October 2014

Since the penetration level of wind energy is continuously increasing, the negative impact caused by the fluctuation of wind power output needs to be carefully managed. This paper proposes a novel real-time coordinated control algorithm based on a wavelet transform to mitigate both short-term and long-term fluctuations by using a hybrid energy storage system (HESS). The short-term fluctuation is eliminated by using an electric double-layer capacitor (EDLC), while the wind-HESS system output is kept constant during each 10-min period by a Ni-MH battery (NB). State-of-charge (SOC) control strategies for both EDLC and NB are proposed to maintain the SOC level of storage within safe operating limits. A ramp rate limitation (RRL) requirement is also considered in the proposed algorithm. The effectiveness of the proposed algorithm has been tested by using real time simulation. The simulation model of the wind-HESS system is developed in the real-time digital simulator (RTDS)/RSCAD environment. The proposed algorithm is also implemented as a user defined model of the RSCAD. The simulation results demonstrate that the HESS with the proposed control algorithm can indeed assist in dealing with the variation of wind power generation. Moreover, the proposed method shows better performance in smoothing out the fluctuation and managing the SOC of battery and EDLC than the simple moving average (SMA) based method.
Predictiveness of Disease Risk in a Global Outreach Tourist Setting in Thailand Using Meteorological Data and Vector-Borne Disease Incidences
Authors: Ninphanomchai Suwannapa , Chansang Chitti , Hii Yien , Rocklöv Joacim , Kittayapong Pattamaporn
Published: October 2014

Dengue and malaria are vector-borne diseases and major public health problems worldwide. Changes in climatic factors influence incidences of these diseases. The objective of this study was to investigate the relationship between vector-borne disease incidences and meteorological data, and hence to predict disease risk in a global outreach tourist setting. The retrospective data of dengue and malaria incidences together with local meteorological factors (temperature, rainfall, humidity) registered from 2001 to 2011 on Koh Chang, Thailand were used in this study. Seasonal distribution of disease incidences and its correlation with local climatic factors were analyzed. Seasonal patterns in disease transmission differed between dengue and malaria. Monthly meteorological data and reported disease incidences showed good predictive ability of disease transmission patterns. These findings provide a rational basis for identifying the predictive ability of local meteorological factors on disease incidence that may be useful for the implementation of disease prevention and vector control programs on the tourism island, where climatic factors fluctuate.
Animal Leptospirosis in Latin America and the Caribbean Countries: Reported Outbreaks and Literature Review (2002–2014)
Authors: Petrakovsky Jessica , Bianchi Alejandra , Fisun Helen , Nájera-Aguilar Patricia , Pereira Martha
Published: October 2014

Leptospirosis is a worldwide zoonotic disease whose transmission is linked through multiple factors in the animal-human-ecosystem interface. The data on leptospirosis reported to the World Organization for Animal Health (OIE) for Latin America and Caribbean (LAC) countries/sovereign territories from 2005–2011 were mapped, showing a wide distribution of outbreaks in the region. Tropical terrestrial biomes are the predominate ecosystems showing reports of outbreaks. Climatic and ecological factors were relevant to the occurrence of epidemic outbreaks. The available scientific information from 2002–2014 was summarized to obtain a general overview and identify key issues related to the One Health approach. The primary serological test used for diagnosis and for conducting surveys was the microscopic agglutination test (MAT). Reports regarding the isolation and typing of leptospires were scattered and limited to data from a few countries, but their results revealed considerable biodiversity at the species and serovar levels. A total of six out of 11 currently named pathogenic species were found in the region. There was also high diversity of animal species showing evidence of infection by leptospires, including rodents, pets, livestock and wild animals. Prevention and control measures for leptospirosis should consider issues of animal and human health in the context of ecosystems, the territorial land borders of countries and trade.
Production of Anti-Cancer Agent Using Microbial Biotransformation
Authors: Roh Changhyun , Kang ChanKyu
Published: October 2014

Microbial biotransformation is a great model system to produce drugs and biologically active compounds. In this study, we elucidated the fermentation and production of an anti-cancer agent from a microbial process for regiospecific hydroxylation of resveratrol. Among the strains examined, a potent strain showed high regiospecific hydroxylation activity to produce piceatannol. In a 5 L (w/v 3 L) jar fermentation, this wild type Streptomyces sp. in the batch system produced 205 mg of piceatannol (i.e., 60% yields) from 342 mg of resveratrol in 20 h. Using the product, an in vitro anti-cancer study was performed against a human cancer cell line (HeLa). It showed that the biotransformed piceatannol possessed a significant anticancer activity. This result demonstrates that a biotransformation screening method might be of therapeutic interest with respect to the identification of anti-cancer drugs.
Mediterranean Diet Pyramid: A Proposal for Italian People
Authors: D'Alessandro Annunziata , De Pergola Giovanni
Published: October 2014

Bread was a staple in the traditional Mediterranean diet of the early 1960s, as well as nowadays; however, it was a stone ground sourdough bread in Nicotera and probably in the Greek cohorts of the Seven Countries Study. In the present review, the nutritional characteristics of this food are analyzed in relation to its protective effects on coronary heart disease, metabolic diseases and cancer. According to our traditions, cultural heritage and scientific evidence, we propose that only cereal foods with low glycemic index (GI) and rich in fiber have to be placed at the base of the Mediterranean diet pyramid, whereas refined grains and high GI starchy foods have to be sited at the top.
Are Reductions in Population Sodium Intake Achievable?
Authors: Levings Jessica , Cogswell Mary , Gunn Janelle
Published: October 2014

The vast majority of Americans consume too much sodium, primarily from packaged and restaurant foods. The evidence linking sodium intake with direct health outcomes indicates a positive relationship between higher levels of sodium intake and cardiovascular disease risk, consistent with the relationship between sodium intake and blood pressure. Despite communication and educational efforts focused on lowering sodium intake over the last three decades data suggest average US sodium intake has remained remarkably elevated, leading some to argue that current sodium guidelines are unattainable. The IOM in 2010 recommended gradual reductions in the sodium content of packaged and restaurant foods as a primary strategy to reduce US sodium intake, and research since that time suggests gradual, downward shifts in mean population sodium intake are achievable and can move the population toward current sodium intake guidelines. The current paper reviews recent evidence indicating: (1) significant reductions in mean population sodium intake can be achieved with gradual sodium reduction in the food supply, (2) gradual sodium reduction in certain cases can be achieved without a noticeable change in taste or consumption of specific products, and (3) lowering mean population sodium intake can move us toward meeting the current individual guidelines for sodium intake.
Nanomechanical DNA Origami pH Sensors
Authors: Kuzuya Akinori , Watanabe Ryosuke , Yamanaka Yusei , Tamaki Takuya , Kaino Masafumi , Ohya Yuichi
Published: October 2014

Single-molecule pH sensors have been developed by utilizing molecular imaging of pH-responsive shape transition of nanomechanical DNA origami devices with atomic force microscopy (AFM). Short DNA fragments that can form i-motifs were introduced to nanomechanical DNA origami devices with pliers-like shape (DNA Origami Pliers), which consist of two levers of 170-nm long and 20-nm wide connected at a Holliday-junction fulcrum. DNA Origami Pliers can be observed as in three distinct forms; cross, antiparallel and parallel forms, and cross form is the dominant species when no additional interaction is introduced to DNA Origami Pliers. Introduction of nine pairs of 12-mer sequence (5'-AACCCCAACCCC-3'), which dimerize into i-motif quadruplexes upon protonation of cytosine, drives transition of DNA Origami Pliers from open cross form into closed parallel form under acidic conditions. Such pH-dependent transition was clearly imaged on mica in molecular resolution by AFM, showing potential application of the system to single-molecular pH sensors.
Increasing the Effectiveness of the “Great Green Wall” as an Adaptation to the Effects of Climate Change and Desertification in the Sahel
Authors: O'Connor David , Ford James
Published: October 2014

The Great Green Wall (GGW) has been advocated as a means of reducing desertification in the Sahel through the planting of a broad continuous band of trees from Senegal to Djibouti. Initially proposed in the 1980s, the plan has received renewed impetus in light of the potential of climate change to accelerate desertification, although the implementation has been lacking in all but two of 11 countries in the region. In this paper, we argue that the GGW needs modifying if it is to be effective, obtain the support of local communities and leverage international support. Specifically, we propose a shift from planting trees in the GGW to utilizing shrubs (e.g., Leptospermum scoparium, Boscia senegalensis, Grewia flava, Euclea undulata or Diospyros lycioides), which would have multiple benefits, including having a faster growth rate and proving the basis for silvo-pastoral livelihoods based on bee-keeping and honey production.
Scenario-Based Analysis on Water Resources Implication of Coal Power in Western China
Authors: Yuan Jiahai , Lei Qi , Xiong Minpeng , Guo Jingsheng , Zhao Changhong
Published: October 2014

Currently, 58% of coal-fired power generation capacity is located in eastern China, where the demand for electricity is strong. Serious air pollution in China, in eastern regions in particular, has compelled the Chinese government to impose a ban on the new construction of pulverized coal power plants in eastern regions. Meanwhile, rapid economic growth is thirsty for electric power supply. As a response, China planned to build large-scale coal power bases in six western provinces, including Inner Mongolia, Shanxi, Shaanxi, Xinjiang, Ningxia and Gansu. In this paper, the water resource implication of the coal power base planning is addressed. We find that, in a business-as-usual (BAU) scenario, water consumption for coal power generation in these six provinces will increase from 1130 million m3 in 2012 to 2085 million m3 in 2020, experiencing nearly a double growth. Such a surge will exert great pressure on water supply and lead to serious water crisis in these already water-starved regions. A strong implication is that the Chinese Government must add water resource constraint as a critical point in its overall sustainable development plan, in addition to energy supply and environment protection. An integrated energy-water resource plan with regionalized environmental carrying capacity as constraints should be developed to settle this puzzle. Several measures are proposed to cope with it, including downsizing coal power in western regions, raising the technical threshold of new coal power plants and implementing retrofitting to the inefficient cooling system, and reengineering the generation process to waterless or recycled means.
Les niveaux de développement en Méditerranée : divergences et convergences (Development levels in mediterranean area : divergences and convergences)
Authors: Semmoud Bouziane
Published: October 2014

The Mediterranean area appears less as a gradient of levels of development than an economic and social fracture line between its two banks. Inequalities do not cease to be worsened between a under way community Europe of homogenization by correction and a South bank including also western Balkans, marked by internal divergences. The evolution is not anything in constrained by mediocre interdependences and non-existent solidarity between countries of the South and East bank and an euro - Mediterranean partnership that can not compensate the crescent inegalization of the powerful mechanisms of globalisation.
Italie, interface Nord-Sud : une occasion manquée ? (Italia, North-South interface : a missed opportunity ?)
Authors: Rivière Dominique
Published: October 2014

L 'exemple de l 'Italie illustre les limites de la problématique de la Méditerranée « interface Nord-Sud ». Les représentations officielles du territoire issues des institutions locales, nationales et européennes, diffusent l'image d'une Méditerranée trait d'union, mais la réalité économique, ici envisagée sous l'angle des échanges commerciaux et des ports, reste dominée par un tropisme septentrional et par l 'intégration européenne. Cet exemple conduit à s 'interroger sur le rôle intégrateur de l'Union européenne à travers sa politique régionale et euro-méditerranéenne.
De la biologie à la géographie de la conservation (From conservation biology to conservation geography)
Authors: Mathevet Raphaël , Poulin Brigitte
Published: October 2014

During the 1990s, the biodiversity became a major issue at the global scale. The Conservation Biology aims to understand the root-causes of the biodiversity loss, to stop it and to promote the wise use of natural resources. However, the multi-field approach recommended by its founders often contrast with a lack of integration of social and economical issues. Aiming to prevent geodiversity loss, the geographers can use their knowledge to initiate a Conservation Geography that would contribute to a more integrative approach by extending the study of biodiversity to the study of geodisparity.
Cartographie géomorphologique et cartographie des risques (Geomorphological mapping and risks mapping)
Authors: Marre Alain
Published: October 2014

The geomorphological maps were created in the beginning of the XXth century. But, it's after 1950 that they were a complete tool for research. Several methods were used in different country. In the same time, other cartographic tools were developed for the applied research. Today, the two methodologies were unified. The development of new techniques (coloured stamp, remote sensing, GIS) have allowed a better adaptation to the aims of this tool.
Les cafés dans la ville (à travers l'exemple lyonnais) (Cafes in the city, through the exemple of Lyon)
Authors: Gunther-Porcarelli Sophie
Published: October 2014

On a toujours pu se restaurer au café et les établissements qui n'offrent pas aujourd'hui cette possibilité sont rares. Certains limitent, le temps du déjeuner, la vente au comptoir, d'autres encore l'abandonnent pour se consacrer uniquement à la restauration. Au café, la nourriture est simple et sans fioritures, et la pratique du repas exclusivement liée à la pause déjeuner. Ainsi, contrairement à la pratique du restaurant, qui s 'inscrit dans le cadre temporel des loisirs, celle du café renvoie plus volontiers au cadre temporel du travail. En satisfaisant désormais la demande de tous ceux qui, éloignés de leur domicile, ont besoin de prendre un repas rapide, les cafés se sont progressivement inscrits dans le marché de la restauration commerciale en se positionnant aujourd'hui sur le créneau d'une restauration économique et populaire, ancrée dans la quotidienneté.
Mobile Ethnography: A Pioneering Research Approach for Customer-Centered Destination Management
Authors: Stickdorn Marc , Frischhut Birgit , Schmid Josef S.
Published: October 2014

Since customers increasingly base purchase decisions on online reviews, tourism has to constantly manage and evaluate the whole service chain from the guests' perspective. Service design as a contemporary approach provides methods to analyze and visualize service chains in a holistic
and usercentered manner. A customer journey map visualizes a sequence of direct and indirect touchpoints. Touchpoints are moments in which customers encounter a certain brand or destination from their first online search, their evaluation through social media, and the booking process, as well
as the travel and stay itself and writing subsequent online reviews. The intentional design of service systems through the eyes of customers is becoming fundamental to compete for customer's satisfaction. Service design builds on ethnographic research of real-life customers. However, quantitative
and classic ethnographic research methods tend to fail when applied on the spacial scope and temporal extension of customer journeys in the field of tourism. In consequence, the innovative approach of mobile ethnography was developed to overcome this problem through integrating tourists as
active investigators using smartphones. Mobile ethnography contrasts with other quantitative and qualitative research methods through its open approach. It is the guests who decide what is a touchpoint during their individual customer journey. This article reports on an EU-funded pilot study
applying mobile ethnography in seven European tourism destinations. The findings of the study in St. Anton, Austria demonstrate the research design of mobile ethnographic research for tourism destinations and indicate its potential to iteratively improve the customer experience in a destination.
Disputes on Nature-Based Tourism Development in Northern Peninsular Malaysia
Authors: Marzuki Azizan , Rofe Matthew , Mohd Hashim Nor Arbaayah
Published: October 2014

Nature-based tourism is an increasingly significant economic resource for developing countries. However, in such countries the development and management of nature-based tourism destinations are bedeviled by structural and operational limitations in local planning processes. The Malaysian
experience provides a salient case in point. This article outlines the problems and constraints facing local and national decision makers during the development and promotion of nature-based tourism in the State of Perlis. Three key governance issues constraining the effective development
of natural tourism opportunities are discussed. These issues are identified as (1) weaknesses of government policies, (2) disorganized administration systems, and (3) limited operational budget. The article proposes that in order for the State of Perlis to pursue and develop a sustainable
nature-based tourism industry these issues must be urgently addressed.
Dolutegravir versus Placebo in Subjects Harbouring HIV-1 with Integrase Inhibitor Resistance Associated Substitutions: 48-Week Results from VIKING-4, a Randomized Study
Authors: Akil Bisher , Blick Gary , Hagins Debbie P , Ramgopal Moti N , Richmond Gary J , Samuel Rafik M , Givens Naomi , Vavro Cindy , Song Ivy H , Wynne Brian , Ait-Khaled Mounir ,   the VIKING-4 study team
Published: October 2014

Background

The Phase III VIKING-3 study demonstrated that dolutegravir (DTG) 50 mg twice daily was efficacious in antiretroviral therapy (ART)-experienced subjects habouring raltegravir- and/or elvitegravir-resistant HIV-1. VIKING-4 (ING116529) included a placebo-controlled 7-day monotherapy phase to demonstrate that short-term antiviral activity was attributable to DTG.

Methods

VIKING-4 is a Phase III randomized, double-blind study in therapy-experienced adults with integrase inhibitor (INI)-resistant virus randomized to DTG 50 mg twice daily or placebo while continuing their failing regimen (without raltegravir or elvitegravir) for 7 days (clinicaltrials.gov identifier NCT01568892). At day 8, all subjects switched to open-label DTG 50 mg twice daily and optimized background therapy including ≥1 fully active drug. The primary end point was change from baseline in plasma HIV-1 RNA at day 8.

Results

The study population ( n=30) was highly ART-experienced with advanced HIV disease. Patients had extensive baseline resistance to all approved antiretroviral classes. Adjusted mean change in HIV-1 RNA at day 8 was -1.06 log10 copies/ml for the DTG arm and 0.10 log10 copies/ml for the placebo arm (treatment difference -1.16 log10 copies/ml [-1.52, -0.80]; P<0.001). Overall, 47% and 57% of subjects had plasma HIV-1 RNA <50 and <400 copies/ml at week 24, and 40% and 53% at week 48, respectively. No discontinuations due to drug-related adverse events occurred in the study.

Conclusions

The observed day 8 antiviral activity in this highly treatment-experienced population with INI-resistant HIV-1 was attributable to DTG. Longer-term efficacy (after considering baseline ART resistance) and safety during the open-label phase were in-line with the results of the larger VIKING-3 study.
Inconsistent Treatment with Disease-modifying Antirheumatic Drugs: A Longitudinal Data Analysis
Authors: Mjaavatten Maria D. , Radner Helga , Yoshida Kazuki , Shadick Nancy A. , Frits Michelle L. , Iannaccone Christine K. , Kvien Tore K. , Weinblatt Michael E. , Solomon Daniel H.
Published: October 2014

Objective.

Current recommendations advocate treatment with disease-modifying antirheumatic drugs (DMARD) in all patients with active rheumatoid arthritis (RA). We investigated the frequency of and reasons for inconsistent DMARD use among patients in a clinical rheumatology cohort.

Methods.

Patients in the Brigham Rheumatoid Arthritis Sequential Study were studied for DMARD use (any or none) at each semiannual study timepoint during the first 2 study years. Inconsistent use was defined as DMARD use at ≤ 40% of study timepoints. Characteristics were compared between inconsistent and consistent users (> 40%), and factors associated with inconsistent DMARD use were determined through multivariate logistic regression. A medical record review was performed to determine the reasons for inconsistent use.

Results.

Of 848 patients with ≥ 4 out of 5 visits recorded, 55 (6.5%) were inconsistent DMARD users. Higher age, longer disease duration, and rheumatoid factor negativity were statistically significant correlates of inconsistent use in the multivariate analyses. The primary reasons for inconsistent use identified through chart review, allowing for up to 2 co-primary reasons, were inactive disease (n = 28, 50.9%), intolerance to DMARD (n = 18, 32.7%), patient preference (n = 7, 12.7%), comorbidity (n = 6, 10.9%), DMARD not being effective (n = 3, 5.5%), and pregnancy (n = 3, 5.5%). During subsequent followup, 14/45 (31.1%) inconsistent users with sufficient data became consistent users of DMARD.

Conclusion.

A small proportion of patients with RA in a clinical rheumatology cohort were inconsistent DMARD users during the first 2 years of followup. While various patient factors correlate with inconsistent use, many patients re-start DMARD and become consistent users over time.
Systèmes de contrôle interactifs et théories de l'apprentissage : une relecture des travaux de R. Simons à l'aune des théories piagétiennes
Authors: Dambrin Claire , Löning Hélène
Published: October 2014

Résumé Depuis ses articles fondateurs, les travaux de Simons ont été largement cités dans la littérature en contrôle de gestion. Notamment, une littérature qui s’intéresse aux liens entre stratégie, contrôle et performance utilise comme cadre de référence la typologie des systèmes de contrôle (diagnostique-interactif ). L’utilisation des travaux du chercheur nous semble toutefois limitée, car chez Simons, les systèmes de contrôle sont structurants de l’apprentissage managérial. Nous nous appuyons sur une théorie structuraliste en psychologie cognitive, (Piaget, 1930, 1931, 1934, 1935, 1949, 1966, 1968), pour proposer une analyse de contenu des travaux de Simons (1987, 1990, 1991, 1994, 1995, 2000), organisée autour de quatre thématiques tirées de notre lecture de Piaget : le rôle du langage des outils de contrôle, l’interactivité des systèmes de contrôle, le lien entre stratégie et contrôle, et enfin l’intégration de l’incertitude dans les systèmes de contrôle. Au-delà, nous cherchons à mettre en avant les apports de la pensée piagétienne pour l’ensemble du champ du contrôle, en questionnant dans quelle mesure la disciplinarisation-structure du contrôle, et de ses outils, est aussi source d’émancipation, donc de production de connaissances.
Évaluation de la performance des managers : L'effet de l'ordre de présentation et de l'importance relative des indicateurs financiers et non financiers
Authors: Cauvin Éric , Neumann Bruce R. , Roberts Michael L.
Published: October 2014

Résumé Le débat sur l’importance des indicateurs non financiers et financiers dans le processus d’évaluation des performances est loin d’être clos. L’objectif de notre recherche est d’examiner, de façon expérimentale, les facteurs qui influencent le choix des évaluateurs en faveur des indicateurs financiers ou non financiers dans l’évaluation des performances d’un manager. Nous avons ainsi d’une part manipulé l’ordre de présentation des indicateurs financiers et non financiers dans le but de tester si les limitations cognitives conduisaient les évaluateurs à considérer seulement les premiers indicateurs qui leur étaient présentés. D’autre part, nous avons manipulé l’importance relative perçue des indicateurs financiers afin d’examiner si le biais en faveur des indicateurs financiers, souvent démontré, pouvait être expliqué par la nature même de ces indicateurs.
Politique de réduction des coûts et communication financière : ritualisme, opportunisme ou nomadisme ?
Authors: Rivière Anne
Published: October 2014

Résumé Régulièrement, les groupes français annoncent des politiques de réduction des coûts (ou « PRC »), qui s’inscrivent dès lors dans leur communication financière volontaire. Notre recherche s’appuie ainsi sur le modèle de communication financière de Gibbins, Richardson & Waterhouse (1990) pour étudier comment et pourquoi les entreprises françaises cotées annoncent volontairement des PRC. Le modèle initial – adapté au contexte français et aux PRC – est testé empiriquement sur 89 communiqués d’annonce via une analyse de contenu. Les résultats font apparaître, en plus de l’opportunisme et du ritualisme prédits par le modèle, une troisième position de communication, qualifiée de nomadisme. Les facteurs internes et externes influençant ces trois positions de communication sont également empiriquement testés.
L'imputation des charges indirectes en France de 1914 aux années 1950 : l'évolution vers la simplicité
Authors: Levant Yves , Zimnovitch Henri
Published: October 2014

L’imputation des charges indirectes est un des problèmes majeurs du calcul de coût dont nombreux travaux historiques ont éclairé l’évolution. En s’intéressant aux solutions qui furent proposées en France sur la période qui va de 1914 aux années 1950, l’article montre qu’il s’agit à chaque fois de trouver un équilibre entre trois exigences : un souci de précision, un besoin d’opérationnalité pour le personnel administratif et comptable, une intelligibilité pour les dirigeants et ingénieurs qui décident du modèle qui sera installé dans leur entreprise. Le rôle des différentes méthodes d’équivalence qui furent imaginées entre 1914 et les années 1950 permet de vérifier les termes de ce compromis. Pour comprendre les raisons qui ont conduit à l’émergence de ces nouvelles méthodes, les profonds changements idéologiques, politiques, économiques et sociaux, survenus alors, sont rappelés en soulignant leur influence sur les fonctions qui étaient assignées au coût. Au-delà de ces forces, l’article montre le déterminisme logique mais aussi la part des individus dans cette histoire de l’allocation des frais généraux.
ARTICLE RETIRÉ : Technotesto : biopolitiques des masculinités tr(s)ans hommes
Authors: Bourcier Marie-Hélène
Published: October 2014

Résumé En relisant l’autobiographie de Max Wolf Valerio, The Testosterone Files : My Hormonal and Social Transformation from female to male , parue en 2006, et compte tenu des réappropriations dont font actuellement l’objet des technologies biopolitiques comme l’autobiographie et la prise d’hormones par les transhommes, nous verrons comment le féminisme radical lesbien séparatiste peut ironiquement produire un machisme à la fois testostéroné et féministe et conduire à une réinvention de son corps et de sa sexualité. In fine , c’est une nouvelle prolifération des masculinités et de corps inédits qui se profile et dont ne sauraient rendre compte des approches s’appuyant sur la question de la reproduction aliénante ou de l’imitation non plus que les ‘masculinités féminines’ subversives tant célébrées par Halberstam et la théorie queer de la première vague.
Peignes en aluminium pour poilus. Autour des occurrences du mot « aluminium » dans Ceux de 14 de Maurice Genevoix
Authors: Péjaudier Hervé
Published: October 2014

La Première Guerre mondiale a été l’occasion d’un élargissement des usages de l’aluminium, que ce soit dans le domaine des transports, de l’armement ou de l’équipement militaire. Faisant suite à une première étude consacrée par l’auteur aux écrits de Guillaume Apollinaire, cet article prolonge l’exploration des occurrences du mot « aluminium » dans l’œuvre des écrivains témoins de la Première Guerre mondiale, en se penchant sur le roman de Maurice Genevoix, Ceux de 14 . Associé aux moments de désœuvrement, l’aluminium qualifie des objets communs de la vie quotidienne des soldats : un quart, une écuelle et, plus surprenant, des peignes. Son évocation confère aux objets une dimension magique, attirant le danger tout en conjurant la mort.
ARTICLE RETIRÉ : Théâtre et confrontation à la violence
Authors: Groulard Guillaume
Published: October 2014

Après avoir vu jouer, par les comédiens du théâtre-forum, une situation comportant une violence sur un ou des individus, le public est invité à débattre et à proposer des solutions de changement. Le spectateur devient acteur, remplace un des personnages. La scène est ainsi rejouée en vue d’expérimenter d’autres issues.
L'ouïe de l'Annonciation. L'importance de l'ouïe et de la voix dans l'hystérie
Authors: Bruley Françoise
Published: October 2014

En partant de l’idée de Christopher Bollas, comme quoi la famille type de l’hystérique est celle de la Sainte Famille, l’auteur explore, à sa façon, le rôle de l’ouïe dans l’Annonciation et dans la naissance virginale. C’est à partir de cette approche de l’hystérie qu’elle revisite la cure de Dora, la jeune patiente de Freud.
Écrire et dire
Authors: Bala Sancho
Published: October 2014

Écrire et dire, voilà comment on pourrait définir le principe fondamental de l’atelier slam à Casita. En partant de son expérience personnelle avec l’écriture, l’auteur tente d’analyser les différents paramètres qui sont mis en jeu à travers un groupe thérapeutique pour adolescents.
Arythmies
Authors: Beldent Véronique
Published: October 2014

Pour qu’il y ait rythme vivant, un certain degré d’arythmie est nécessaire. Massive ou défensive, elle est alors chaos ou abîme qui immobilise. Entre l’engloutissement dans le chaos et l’émergence d’un ordre, se situe le point d’origine du rythme. Quand l‘arythmie se fait syncope elle vient animer et rompre la continuité. Avec elle, c’est la temporalité de la discontinuité de l’instant qui se dévoile permettant une ouverture. Expérience d’artiste (Cézanne, Webern), elle est aussi celle de tout parcours analytique dans sa singularité rythmique entraînant l’analyste dans une rythmanalyse.
ARTICLE RETIRÉ : Amnésies et hypermnésies du sujet entre deux cultures
Authors: Lhomme-Rigaud Colette
Published: October 2014

Résumé La séparation d’avec les grands-parents restés dans le pays d’origine est un traumatisme essentiel dans des psychopathologies affectant les préadolescents ou adolescents dont les parents ont émigré. L’ascendance qui est constitutive de leur passé participe, par son absence, à la constitution dune fragilité narcissique, difficilement réductible. Ce trauma pouvait se rencontrer dans d’autres cas de figures, comme dans le cas, ici rapporté, d’une préadolescente adoptée, inscrite dans deux cultures et coupée, à un moment de sa vie, de la présence de ceux qui avaient été constitués comme ses ascendants. À travers des processus phobiques et des contenus oniriques (principalement des monstres), elle parvint à atteindre d’abord des souvenirs écrans puis de véritables réminiscences.
ARTICLE RETIRÉ : Sur la nostalgie. La mémoire tourmentée
Authors: Starobinski Jean
Published: October 2014

Résumé Comment la dénomination médicale de la « nostalgie » est-elle apparue ? On propose ici d’envisager un processus en deux temps. En un premier temps, la médecine de la fin du xvii e siècle s’est déclarée compétente pour l’explication de symptômes psychologiques qui venaient à sa connaissance. En un second temps, la médecine a étayé sa description par des exemples recueillis dans le domaine littéraire classique. Elle a inscrit notamment Homère, Virgile, Ovide à l’appui du tableau qu’elle construisait de la nostalgie. Dès le xviii e siècle, il a été suggéré que la perte de rapports personnels, surtout pour les enfants, était plus importante que le « changement d’air » généralement allégué.
L'Un inconscient Monothéisme et psychanalyse
Authors: Assoun Paul-Laurent
Published: October 2014

Résumé Si à première vue la croyance en un Dieu semble l’idée la plus simple, cette simplification, la réduction qu’elle suppose relève d’un travail historique et psychique complexe. Cet article tente d’en saisir le ressort inconscient, en partant du repérage de la position de Freud devant l’énigme monothéiste.
L'infertilité comme avatar du lien ravageant fille-mère
Authors: Leben-Loison Liliane
Published: October 2014

Dans cet article, nous nous intéressons aux relations fille-mère dans le cas où la fille ne réussit pas à devenir mère (l’infertilité, ici, n’a pas d’étiologie médicale diagnostiquée). Nous présentons, tout d’abord, une étude théorique centrée sur ces deux thèmes. Puis l’étude clinique analyse deux témoignages de femmes présentant ce symptôme. Elle révèle « le ravage » entre elles et leur mère, avec ses aspects communs mais aussi ses variations inhérentes à la singularité de chacune. Ces femmes ne peuvent se servir de leur père pour se détacher de leur mère. L’infertilité, dans leur discours, devient un moyen de se différencier d’elle.
Coma : une absence de soi à soi ?
Authors: Minjard Raphaël
Published: October 2014

L’éveil de coma confronte à une énigme. Comment entendre la souffrance du patient dans cette confluence de détresses organiques et psychiques, et comment accompagner le malade dans son cheminement vers l’éveil ? Cet article rend compte de la nécessité de penser les mécanismes psychiques de l’éveil de coma au plus près du patient et de son environnement. Il propose de faire le lien entre l’état de précarité vitale et la question de la dynamique psychique en ouvrant sur la question du perceptif, du délire et de la mémoire. Enfin, il met en évidence le travail de lien et la place du psychologue comme élément de l’équipe de soins en réanimation.
Érotisme de la pensée magique
Authors: Fernandez Philippe
Published: October 2014

Le texte propose l’analyse d’une « pensée magique » chez « l’homme aux rats », chez le président Schreber, use de la clinique d’un patient maniaco-dépressif pour comparer sa façon d’être à celle de l’obsessionnel à partir de l’expression d’une de ses pensées, pour enfin inscrire ces productions pathologiques dans les manquements liés à l’analyse du transfert. Il en ressort que la pensée magique comme expression pathologique peut être sous-tendue par la pulsion de vie. En cela, non seulement elle se fait vestige de la mégalomanie infantile correspondant ontologique de l’époque préscientifique, mais elle permet d’inscrire le sujet parlant dans son parcours singulier et ce malgré sa pathologie.
La symbiose partielle, une dimension d'entre-corps dans l'approche thérapeutique des psychoses
Authors: de Luca-Bernier Catherine
Published: October 2014

Dans l’accompagnement de la psychose, le soignant se voit confronté à la réalité du corps vécu du psychotique ainsi qu’à ses limites dans tous les actes de la vie quotidienne. Les éprouvés dus à cette proximité sont qualifiés de « contaminations » dans la nosographie. L’élaboration de ces manifestations dans le lien transférentiel permet une requalification de ces éprouvés en possibles thérapeutiques par le processus de symbiose partielle, dont la conceptualisation est proposée ici.
Le fétiche comme condition de la perversion. Tout sujet pervers est-il fétichiste ? Exemples cliniques
Authors: Martin-Mattera Patrick , Lévy Alexandre , Saïet Mathilde
Published: October 2014

Cet article analyse la fonction du fétiche dans la perversion et tend à définir cet objet comme une composante indispensable de l’organisation psychique perverse. Les auteurs s’appuient principalement sur deux cas cliniques, l’un typique du fétichisme, l’autre en apparence plus éloigné. Après avoir mis en relation comparative les notions de fétiche, fantasme et transgression, l’article interroge la « structure » perverse et la place de ces éléments dans la dynamique qui la caractérise, avant de considérer le fétiche comme une condition de la jouissance de l’Autre.
Un outil technique précieux : « le travail de soutien au Moi de l'enfant »
Authors: Guimaraes Rosa
Published: October 2014

Résumé Au cours d’une recherche universitaire reconstruisant la démarche de Ferenczi sur l’impact du trauma et de l’environnement psychoaffectif de l’enfant sur son développement, un outil technique a été élaboré : « Le travail de soutien au Moi de l’enfant. » Il est né de la confrontation des perspectives ouvertes par des psychanalystes se réclamant d’une filiation à Ferenczi sur ces deux lignes de recherche : M. et A. Bálint, I. Hermann, N. Abraham et M. Torok en France. Hermann, précédent Bowlby et la théorie de l’attachement, a travaillé sur deux instincts : l’instinct de cramponnement et l’instinct de recherche. Le travail de soutien au Moi de l’enfant confirme les hypothèses cliniques de Ferenczi sur le trauma et l’impact de la pensée du parent sur le développement de l’enfant. De plus, cet outil se révèle avoir des effets sur la réparation des effets du trauma et agit comme stimulateur du développement, de la conscience réflexive, du langage, de la tonicité, ceci jusqu’à l’âge de 7-8 ans. S’appuyant sur une observation et une narration du parent à l’enfant, cet outil requiert la capacité du parent à penser l’enfant. Un accompagnement thérapeutique familial est nécessaire lors de situations traumatiques complexes.