bluuebunny/crossref_metadata_2025 huggingface dataset:
Broader and safer clinically-relevant activities of pentadecanoic acid compared to omega-3: Evaluation of an emerging essential fatty acid across twelve primary human cell-based disease systems
Authors: Venn-Watson Stephanie K. , Butterworth Camden N.
Published: May 2022

A growing body of evidence supports that pentadecanoic acid (C15:0), an odd-chain saturated fat found in butter, is an essential fatty acid that is necessary in the diet to support long-term metabolic and heart health. Here, dose dependent and clinically relevant cell-based activities of pure C15:0 (FA15TM) were compared to eicosapentaenoic acid (EPA), a leading omega-3 fatty acid, as well as to an additional 4,500 compounds. These studies included 148 clinically relevant biomarkers measured across 12 primary human cell systems, mimicking various disease states, that were treated with C15:0 at four different concentrations (1.9 to 50 μM) and compared to non-treated control systems. C15:0 was non-cytotoxic at all concentrations and had dose dependent, broad anti-inflammatory and antiproliferative activities involving 36 biomarkers across 10 systems. In contrast, EPA was cytotoxic to four cell systems at 50 μM. While 12 clinically relevant activities were shared between C15:0 and EPA at 17 μM, C15:0 had an additional 28 clinically relevant activities, especially anti-inflammatory, that were not present in EPA. Further, at 1.9 and 5.6 μM, C15:0 had cell-based properties similar to bupropion (Pearson’s scores of 0.78), a compound commonly used to treat depression and other mood disorders. At 5.6 μM, C15:0 mimicked two antimicrobials, climabazole and clarithromycin (Pearson’s scores of 0.76 and 0.75, respectively), and at 50 μM, C15:0 activities matched that of two common anti-cancer therapeutics, gemcitabine and paclitaxel (Pearson’s scores of 0.77 and 0.74, respectively). In summary, C15:0 had dose-dependent and clinically relevant activities across numerous human cell-based systems that were broader and safer than EPA, and C15:0 activities paralleled common therapeutics for mood disorders, microbial infections, and cancer. These studies further support the emerging role of C15:0 as an essential fatty acid.
Spatiotemporal trends in bed bug metrics: New York City
Authors: Hacker Kathryn P. , Greenlee Andrew J. , Hill Alison L. , Schneider Daniel , Levy Michael Z.
Published: May 2022

Bed bug outbreaks pose a major challenge in urban environments and cause significant strain on public resources. Few studies have systematically analyzed this insect epidemic or the potential effects of policies to combat bed bugs. Here we use three sources of administrative data to characterize the spatial-temporal trends of bed bug inquiries, complaints, and reports in New York City. Bed bug complaints have significantly decreased (p < 0.01) from 2014–2020, the absolute number of complaints per month dropping by half (875 average complaints per month to 440 average complaints per month); conversely, complaints for other insects including cockroaches and flies did not decrease over the same period. Despite the decrease of bed bug complaints, areas with reported high bed bug infestation tend to remain infested, highlighting the persistence of these pests. There are limitations to the datasets; still the evidence available suggests that interventions employed by New York City residents and lawmakers are stemming the bed bug epidemic and may serve as a model for other large cities.
Generating dynamic gene expression patterns without the need for regulatory circuits
Authors: Shah Sahil B. , Hill Alexis M. , Wilke Claus O. , Hockenberry Adam J.
Published: May 2022

Synthetic biology has successfully advanced our ability to design and implement complex, time-varying genetic circuits to control the expression of recombinant proteins. However, these circuits typically require the production of regulatory genes whose only purpose is to coordinate expression of other genes. When designing very small genetic constructs, such as viral genomes, we may want to avoid introducing such auxiliary gene products while nevertheless encoding complex expression dynamics. To this end, here we demonstrate that varying only the placement and strengths of promoters, terminators, and RNase cleavage sites in a computational model of a bacteriophage genome is sufficient to achieve solutions to a variety of basic gene expression patterns. We discover these genetic solutions by computationally evolving genomes to reproduce desired gene expression time-course data. Our approach shows that non-trivial patterns can be evolved, including patterns where the relative ordering of genes by abundance changes over time. We find that some patterns are easier to evolve than others, and comparable expression patterns can be achieved via different genetic architectures. Our work opens up a novel avenue to genome engineering via fine-tuning the balance of gene expression and gene degradation rates.
Poor welfare compromises testicle physiology in breeding boars
Authors: Bernardino Thiago , Carvalho Carla Patricia Teodoro , Batissaco Leonardo , Celeghini Eneiva Carla Carvalho , Zanella Adroaldo José
Published: May 2022

In commercial pig breeding farms, boars are often exposed to stressful situations, such as confined housing conditions, inadequate environmental temperature, food restriction, lameness, diseases, among other challenges. Confined housing conditions, such as crates, are reported as a major source of stress for pregnant sows, and were banned in the UK and in Europe, however there is limited information about the impact of this housing system for boars. The goal of this study was to investigate the impact of three different housing conditions for boars and the consequence on the testicles. We studied 27 crossbred boars (F1 large white and landrace), housed in crates (n = 9), pens (n = 9), or enriched pens (n = 9), during 10 weeks. We collected data of scrotal superficies mean temperature (SSMT) with a thermal camera; we measured testicular parenchyma perfusion (ultrasound evaluation); and we measured sperm characteristics. We found that boars housed in crates had a higher SSMT (p < 0.05) and higher testicular parenchyma perfusion than boars housed in pens and enriched pens (p = 0.01). Regarding the semen features, we found that boars housed in crates showed more agglutinated semen, and higher values of linear curved linear velocity (VCL) than boars housed in pens and enriched pens, both indicators of reduced fertility. These results indicates that boars housed in pens and in enriched pens showed better indicators of testicular health, better sperm motility features (VCL, p = 0.046), and less agglutinated sperm (p < 0;05) than that observed in boars kept in crates.
Validation of the rabbit pain behaviour scale (RPBS) to assess acute postoperative pain in rabbits (Oryctolagus cuniculus)
Authors: Haddad Pinho Renata , Luna Stelio Pacca Loureiro , Esteves Trindade Pedro Henrique , Augusto Justo André , Santilli Cima Daniela , Werneck Fonseca Mariana , Watanabe Minto Bruno , Del Lama Rocha Fabiana , Miller Amy , Flecknell Paul , Leach Matthew C.
Published: May 2022

Considering the widespread use of rabbits in research that potentially causes pain and discomfort and the limited number of pain assessment validated tools in this species, we aimed to develop and validate a scale of acute postoperative pain in rabbits (RPBS). Footage of 58 rabbits from previous studies were used, recorded at ‘baseline’(before orthopaedic and soft tissue surgeries), ‘pain’(after surgery), ‘analgesia’(after analgesic), and ‘24h post’(24 hours after surgery). The videos were randomised and assessed twice by four evaluators, within one-month interval between evaluations. After content validation, RBPS was further refined using the criteria from the validation. According to the principal component analysis, RPBS was considered unidimensional. The intra- and inter-observer reliability was excellent (ICC>0.80) for all evaluators. There was a high Spearman’s correlation of the RPBS with unidimensional scales (>0.80) and a moderate correlation with the Rabbit Grimace Scale (0.68), confirming criterion validity. According to the mixed linear model, the scale was responsive, shown by the increase in pain scores after surgery. Construct validity was confirmed by known-group approach and internal relationships among items. Adequate item-total correlation (>0.3) was observed for all items, except for the attention to the affected area (0.04). The internal consistency was very good (Cronbach’s α coefficient = 0.78; Mcdonald’s ω coefficient = 0.83). The cut-off score for rescue analgesia was ≥3, with an area under the curve >0.95, demonstrating a high discriminatory capacity of the instrument. Scores 3 and 4 were within the uncertainty diagnostic zone. Specificity was 87% and sensitivity was 90%. It was concluded that the RPBS presented content, criterion, and construct validities, responsiveness, and reliability to assess acute pain in rabbits submitted to orthopaedic and soft tissue surgeries. The cut-off for rescue analgesia serves as a basis for the administration of analgesics to rabbits submitted to painful procedures.
Population spatialization at building scale based on residential population index—A case study of Qingdao city
Authors: Mao Zhen , Han Haifeng , Zhang Heng , Ai Bo
Published: May 2022

The study of population spatialization has provided important basic data for urban planning, development, environment and other issues. With the development of urbanization, urban residential buildings are getting higher and higher, and the difference between urban and rural population density is getting larger and larger. At present, most population spatial studies adopt the grid scale, and the population in buildings is evenly divided into various grids, which will lead to the neglect of the population distribution in vertical space, and the authenticity is not strong. In order to improve the accuracy of the population distribution, this paper studied the spatial distribution of population at the building scale, combined the digital surface model (DSM) and the digital elevation model (DEM) to calculate the floor of buildings, and proposed a new index based on the total floor area of residential buildings, called residential population index (RPI). RPI is directly related to the number of people a building can accommodate, so it can effectively estimate the population of both urban and rural areas even if the structure of urban and rural buildings is very different. In addition, this paper combined remote sensing monitoring data with geographic big data and adopted principal component regression (PCR) method to construct RPI prediction model to obtain building-scale population distribution data of Qingdao in 2018, providing ideas for population spatialization research. Through field sampling survey and overall assessment, the results were basically consistent with the actual residential situation. The average error with field survey samples is 14.5%. The R2 is 0.643 and the urbanization rate is 69.7%, which are all higher than WorldPop data set. Therefore, this method can reflect the specific distribution of urban resident population, enhance the heterogeneity and complexity of population distribution, and the estimated results have important reference significance for urban management, urban resource allocation, environmental protection and other fields.
Alprostadil for hypertensive nephropathy: A systematic review and meta-analysis of randomized controlled trials
Authors: Fu Hongfang , Hou Weiwei , Zhang Yang , Hu Xiaoyu
Published: May 2022

We performed a meta-analysis to evaluate the efficacy of alprostadil in the treatment of hypertensive nephropathy. Seven online databases (PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure [CNKI] database, Wanfang Data Knowledge Service Platform, VIP Information Resource Integration Service Platform [cqVIP], and China Biology Medicine Disc [SinoMed]) were searched from inception to January 31, 2022, and a set of clinical indicators for hypertensive nephropathy was selected. The main indicators were 24-h urinary protein, serum creatinine, endogenous serum creatinine clearance rate, blood urea nitrogen, cystatin C, and mean arterial pressure. The methodological quality of the included trials was analyzed using a risk of bias assessment according to the Cochrane Manual guidelines, and a meta-analysis was performed. A random-effects model was implemented to pool the results. A total of 20 randomized controlled trials involving 1441 patients with hypertensive nephropathy were included in this review. Our findings showed that alprostadil had a positive effect on 24-h urinary protein (mean difference [MD] = −0.79, 95% confidence interval [CI] [−1.16, −0.42], P < 0.0001), serum creatinine (MD = −13.83, 95% CI [−19.34, −8.32], P < 0.00001), endogenous serum creatinine clearance rate (MD = 6.09, 95% CI [3.59, 8.59], P < 0.00001), blood urea nitrogen (MD = −6.42, 95% CI [−8.63, −4.21], P < 0.00001), cystatin C (MD = −0.26, 95% CI [−0.34, −0.18], P < 0.00001), and mean arterial pressure levels(MD = −13.65, 95% CI [−16.08, −11.21], P < 0.00001). Compared to conventional treatment alone, alprostadil combined with conventional treatment can improve renal function in patients with hypertensive nephropathy more effectively. However, additional large-scale, multicenter, rigorously designed randomized controlled trials are needed to verify these results. This is the first meta-analysis to evaluate the efficacy of alprostadil for hypertensive nephropathy, and the results may guide clinical practice.
Evaluation of optimal Zernike radial degree for representing corneal surfaces
Authors: Omidi Pooria , Cayless Alan , Langenbucher Achim
Published: May 2022

Tomography data of the cornea usually contain useful information for ophthalmologists. Zernike polynomials are often used to characterize and interpret these data. One of the major challenges facing researchers is finding the appropriate number of Zernike polynomials to model measured data from corneas. It is undeniable that a higher number of coefficients reduces the fit error. However, utilizing too many coefficients consumes computational power and time and bears the risk of overfitting as a result of including unnecessary components. The main objective of the current study is to analyse the accuracy of corneal surface data modelled with Zernike polynomials of various degrees in order to estimate a reasonable number of coefficients. The process of fitting the Zernike polynomials to height data for corneal anterior and posterior surfaces is presented and results are shown for normal and pathological corneas. These results indicate that polynomials of a higher degree are required for fitting corneas of patients with corneal ectasia than for normal corneas.
Sexual reproduction is the null hypothesis for life cycles of rust fungi
Authors: McTaggart Alistair R. , James Timothy Y. , Idnurm Alexander , Park Robert F. , Shuey Louise S. , Demers Michelle N. K. , Aime M. Catherine
Published: May 2022

Sexual reproduction, mutation, and reassortment of nuclei increase genotypic diversity in rust fungi. Sexual reproduction is inherent to rust fungi, coupled with their coevolved plant hosts in native pathosystems. Rust fungi are hypothesised to exchange nuclei by somatic hybridisation with an outcome of increased genotypic diversity, independent of sexual reproduction. We provide criteria to demonstrate whether somatic exchange has occurred, including knowledge of parental haplotypes and rejection of fertilisation in normal rust life cycles.
Tuberculosis caused by Mycobacterium africanum: Knowns and unknowns
Authors: Silva Marta L. , Cá Baltazar , Osório Nuno S. , Rodrigues Pedro N. S. , Maceiras Ana Raquel , Saraiva Margarida
Published: May 2022

Tuberculosis (TB), one of the deadliest threats to human health, is mainly caused by 2 highly related and human-adapted bacteria broadly known as Mycobacterium tuberculosis and Mycobacterium africanum. Whereas M. tuberculosis is widely spread, M. africanum is restricted to West Africa, where it remains a significant cause of tuberculosis. Although several differences have been identified between these 2 pathogens, M. africanum remains a lot less studied than M. tuberculosis. Here, we discuss the genetic, phenotypic, and clinical similarities and differences between strains of M. tuberculosis and M. africanum. We also discuss our current knowledge on the immune response to M. africanum and how it possibly articulates with distinct disease progression and with the geographical restriction attributed to this pathogen. Understanding the functional impact of the diversity existing in TB-causing bacteria, as well as incorporating this diversity in TB research, will contribute to the development of better, more specific approaches to tackle TB.
An anthranilic acid-responsive transcriptional regulator controls the physiology and pathogenicity of Ralstonia solanacearum
Authors: Song Shihao , Sun Xiuyun , Guo Quan , Cui Binbin , Zhu Yu , Li Xia , Zhou Jianuan , Zhang Lian-Hui , Deng Yinyue
Published: May 2022

Quorum sensing (QS) is widely employed by bacterial cells to control gene expression in a cell density-dependent manner. A previous study revealed that anthranilic acid from Ralstonia solanacearum plays a vital role in regulating the physiology and pathogenicity of R. solanacearum. We reported here that anthranilic acid controls the important biological functions and virulence of R. solanacearum through the receptor protein RaaR, which contains helix-turn-helix (HTH) and LysR substrate binding (LysR_substrate) domains. RaaR regulates the same processes as anthranilic acid, and both are present in various bacterial species. In addition, anthranilic acid-deficient mutant phenotypes were rescued by in trans expression of RaaR. Intriguingly, we found that anthranilic acid binds to the LysR_substrate domain of RaaR with high affinity, induces allosteric conformational changes, and then enhances the binding of RaaR to the promoter DNA regions of target genes. These findings indicate that the components of the anthranilic acid signaling system are distinguished from those of the typical QS systems. Together, our work presents a unique and widely conserved signaling system that might be an important new type of cell-to-cell communication system in bacteria.
Aggravating circumstances? The COVID-19-related situational threats against the press in Portugal
Authors: Novais Rui Alexandre
Published: May 2022

This study aims to fill the gap of the practical impediments for journalists properly doing their work during the COVID-19 pandemic over a single country. It is achieved by mapping the situational threats faced by the press in Portugal, as one of the best countries that grant media a free environment to work, which illustrates the challenges faced by media in established democracies. Drawing on the analysis of 34 episodes reported by national and international monitoring bodies over twenty months since the onset of the coronavirus crisis in the country, it concludes that economic threats alongside limitations in accessing information prevailed to the detriment of verbal and physical attacks or smear campaigns and online harassment. Apart from the nuance of the far-right hostility towards the press due to the health restrictions during campaign reporting as a new type of threat manifestation, the remaining threats experienced by the Portuguese media accelerated or aggravated previous trends.
All the small things: Depicting the randomization of grief in (digital) short fiction
Authors: Clark Lynda
Published: May 2022

When I read scholar Tia-Monique Uzor’s recent tweet about how she had been thinking about grieving as a practice and how to hold spaces for collective grief and to make room for grief over seemingly small things, I realized that this was what I had been doing when writing fiction that was obliquely about my sister’s death. The collective grief I had sought was not the public ritual of the funeral, but the asynchronous sharing of short fiction. I needed to grieve not only the big, obvious losses of my sister and way of life during COVID-19 but also all the ‘seemingly small things’ that come together to constitute my experiences of loss. This article is an attempt to reflect on that process and how complex narrative structures can provide a tool for expressing complex emotions and experiences. It considers grief as a multifarious topic and writing techniques for conveying that multiplicity. Finally, it explores technology, randomization and text generation as tools which further expand writers’ expressive capabilities.
The ailing maternal body as a site of incommunicability, unknowability and violence in Willa C. Richards’s ‘Failure to Thrive’
Authors: Lénárt-Muszka Zsuzsanna
Published: May 2022

American author Willa C. Richards’s short story ‘Failure to Thrive’ (2019) thematizes physical, mental and emotional health by centring a young and presumably White American couple and their newborn. The couple have trouble communicating with each other, and crucial pieces of information are withheld from the reader as well. At the same time, numerous references to different types of violence emerge as markers of the maternal throughout the story to such an extent that the maternal body becomes the site not only of difference and unknowability but of violence as well. I anchor my analysis in motherhood studies and argue that motherhood is the discursive lens through which interlocking issues of embodiment, dehumanizing medical practices and diverse types of violence are exposed in ‘Failure to Thrive’. While attending to the narrative design of the story, I demonstrate how the ailing mother becomes a figure on whom the tropes of violence and incommunicability as well as the wide-reaching implications of ill health are mapped out.
‘Les Aliénés’
Authors: Greenberg Joy
Published: May 2022

A short story following a young woman named Bernadette and her stay at a mental hospital in Paris.
The Bloomsbury Handbook to Katherine Mansfield, Todd Martin (ed.) (2021)
Authors: March-Russell Paul
Published: May 2022

Review of: The Bloomsbury Handbook to Katherine Mansfield, Todd Martin (ed.) (2021)

London: Bloomsbury Academic, 534 pp.,

ISBN 978-1-35011-144-8, h/bk, £130.00
It speaks to me
Authors: Machado Sara Monteiro , Ribeiro Vasco , Meneses Raquel
Published: May 2022

The increasing electoral abstention of young people is a global problem that has raised concerns both inside and outside the academy. However, recent research suggests that young people are significantly more likely to vote when causes or issues close to them are at stake. This article explores the influence of context (the Covid-19 and far-right populism) on youth voter turnout. Using a triangulation of methods, data were collected both via a survey (n = 350) answered by a representative sample of young Portuguese people between 18 and 29 years old and through social media analytics (n = 2.373), analyzing the activity of young people in the same age group on Twitter during the 2021 Presidential Election in Portugal. The results point to a strong mobilization power of the rise of far-right populism in young people's turnout, who demonstrate a willingness to express their opposition to these movements through voting. On the contrary, Covid-19 does not seem to be a mobilizing topic that young people are passionate about, but it influences the electoral moment in two ways: negatively, by making it difficult or impossible to vote; positively, by reinforcing attention to the election campaign.
News media and populism
Authors: Silva dos Santos Carlos Vinicius , Santos de Miranda João Manuel
Published: May 2022

The main objective of this analysis is to chart and to characterize scholarship on populism and news media, by identifying the issues and problems, as well as research practices that shape these studies. This article reports the findings of a systematic review of empirical studies on populism and news media (n=218), published in peer-review journals indexed in Scopus and Web of Science databases, until July 2021. Building on the information retrieved from these databases and based on the content analysis of full texts, we seek to identify key characteristics of the studies, such as publication dates, authors, journals, scientific domains and categories, regional focuses, analyzed phenomena, methodological options, or conceptual approaches to the interaction between populism and news media.
O populismo no Brasil
Authors: Mendes André , Silva Terezinha
Published: May 2022

Esse artigo pretende analisar a trajetória política do populista de direita Jair Bolsonaro em direção à presidência do Brasil, com a intensão de questionar o consenso divulgado pela mídia e diversos trabalhos acadêmicos que afirmam ser o ex-capitão um ator político irascível e incapaz de planejamento. Nossa hipótese é que ele utilizou estratégias bem planejadas para chegar à presidência do Brasil em 2018. Para realizar a análise e as reflexões, utilizamos a noção de verdade e discurso em Foucault e de política de Ernesto Laclau e Chantal Mouffe, bem como os conceitos de imagem pública desenvolvido por Wilson Gomes, e enquadramento, baseada na abordagem de Erving Goffman. Após as análises e reflexão sobre os acontecimentos selecionados, a hipótese de que as ações de Bolsonaro não são randômicas e irracionais se mostrou pertinente.
Riera Melis, A., Ortega Villoslada, A. (Eds.) (2020). El Manual de rebudes i dades de la Clavaria Municipal de Mallorca corresponent a l’any 1333 (ADM, MSL/252). Barcelona: Institut d’Estudis Catalans, Secció Històrico- Arqueològica, CXII. 315 pp. ISBN: 978-84-9965-571-0
Authors: Alcover Cateura Pablo José
Published: May 2022

Ressenya: Riera Melis, A., Ortega Villoslada, A. (Eds.) (2020). El Manual de rebudes i dades de la Clavaria Municipal de Mallorca corresponent a l’any 1333 (ADM, MSL/252). Barcelona: Institut d’Estudis Catalans, Secció Històrico- Arqueològica, CXII. 315 pp. ISBN: 978-84-9965-571-0.
Il commercio dei cavalli tra Sardegna e Corona d’Aragona alla fine del XV secolo. Prime considerazioni
Authors: Seche Giuseppe
Published: May 2022

Lo studio propone prime considerazioni sul commercio dei cavalli tra il Regno di Sardegna e i territori della Corona d’Aragona nella seconda metà del XV secolo. L’analisi si basa su 51 licenze di esportazione e consente di ricostruire le dinamiche di un traffico regolato dall’autorità pubblica, evidenziando gli ufficiali impegnati nel controllo e nel rilascio delle relative autorizzazioni. I profili dei soggetti coinvolti sono quelli dei mercanti di professione, cui si aggiungono i membri dell’alta società urbana, con ruoli nell’amministrazione della città o del regno, e coloro che trasportano equini in maniera occasionale. Infine, non mancano gli esponenti del mondo feudale, spesso in affari con i mercanti d’oltremare, i quali possono far valere franchigie, esenzioni fiscali e vantaggiosi legami con i funzionari del regno. Tra i luoghi di destinazione si segnalano le grandi piazze commerciali iberiche (Barcellona, Maiorca e Valenza) e alcune città italiane (Napoli, Piombino e Roma), dove i cavalli potevano essere acquistati da uomini di alto rango (si pensi al sacrestano maggiore Alonso Cortés) ed essere utilizzati anche per ragioni militari o per servizio di stato. Emerge un commercio rischioso ma con grandi margini di guadagno, portato avanti da soggetti specializzati che si avvalgono di navigli con particolari caratteristiche tecniche. Il proseguimento della ricerca consentirà di precisare le conoscenze sul trattamento fiscale riservato ai cavalli e pone già nuove domande sulle pratiche di allevamento, che dovevano rispondere alla continua e regolare richiesta di animali proveniente dal mondo iberico e da quello italiano.
Die Rekonstruktion des bürgerlichen Sommeralltags des Budapester Bürgertums um 1900 anhand publizistisch-literarischer (Selbst)-Darstellungen im Feuilleton des Neuen Pester Journals und des Pester Lloyd
Authors: Gules Christiana
Published: May 2022

A doktori értekezés fő célja a budapesti polgári nyári kultúra művelődéstörténeti rekonstrukciója a német nyelvű, lokális sajtóorgánumok tárcáinak specifikus mediális reprezentációi alapján, különös tekintettel az 1890 és 1914 közötti periódusra. Jelen dolgozat célkitűzése azon jelenségek és problémák elemzése, amelyek egy ilyen változékony és eklektikus anyag tudományos feltárása során felvetődnek. A hipotézis szerint a tárcairodalomban a korabeli kollektív polgári identitás egy lehetséges olvasata fedezhető fel. A dolgozat a századfordulós budapesti társas élet mindennapjainak egy bizonyos szegmensére, kifejezetten a nyári időszakban megjelent, nyári tematikájú cikkekre koncentrál. A tárcák ilyen fókuszú tematikus elemzéséből a nyári kultúrára vonatkozó szövegrészek vizsgálata során rekonstruálható a korabeli napi aktualitások polgári önábrázolása.
A nő helye
Authors: Kothencz-Török Katalin
Published: May 2022

A disszertációban különböző tematikájú és műfajú sorozatokban vizsgálom meg azt, hogy milyen női szerepmodelleket mutatnak be, ezáltal milyen nőiség fogalmakat reprezentálnak. Az egyes fejezetek különböző zsánerű televíziós sorozatokkal foglalkoznak – szituációs komédia és női sorozat, procedurális krimi, boszorkányokat felvonultató szériák, szuperhőssorozatok és queer sorozatok. Tézisem, hogy az első látásra feministának tűnő célkitűzések – amelyek a második hullámos feminizmusból származnak – nem érvényesülnek, mert azokat folytonosan aláássa egy szinte észrevétlenül működő posztfeminista logika.
Predicting Ulcerative Colitis Relapse in Clinical Remission With Fecal Immunochemical Occult Blood Test or Prostaglandin E-Major Urinary Metabolite
Authors: Ishida Natsuki , Matsuura Tomoharu , Asai Yusuke , Miyazu Takahiro , Tamura Satoshi , Tani Shinya , Yamade Mihoko , Iwaizumi Moriya , Hamaya Yasushi , Osawa Satoshi , Furuta Takahisa , Sugimoto Ken
Published: May 2022

INTRODUCTION:

The fecal immunochemical occult blood test (FIT) and prostaglandin E-major urinary metabolite (PGE-MUM) have been reported to predict the relapse of ulcerative colitis (UC) during remission. In this study, we directly compared FIT and PGE-MUM in predicting relapse and examined the effect of disease duration on these biomarkers.

METHODS:

Measurements of 2 biomarkers and endoscopic examination were performed in 73 patients with UC in remission. The patients were followed up for 12 months, and clinical relapse was evaluated. In addition, we divided the patients into long-term disease duration and short-term disease duration groups for analysis.

RESULTS:

Twenty-one patients (28.8%) relapsed within 12 months. FIT and PGE-MUM levels were significantly higher in the relapsed group than in the remission group. Cutoff values of FIT and PGE-MUM for predicting relapse using receiver operating characteristic analysis were 65.0 ng/mL (area under the curve [AUC]: 0.723) and 25.2 μg/g·Cr (AUC: 0.701), respectively. Patients with FIT ≥ 65.0 ng/mL and PGE-MUM ≥ 25.2 μg/g·Cr had a higher risk of clinical relapse. In the short-term disease duration group, the AUCs of FIT were larger than those of PGE-MUM using receiver operating characteristic analysis, in most instances. By contrast, the AUCs of PGE-MUM were larger than those of FIT in most cases in the long-term disease groups.

DISCUSSION:

FIT and PEG-MUM were highly accurate in predicting clinical relapse in UC patients with short and long disease durations in remission, respectively.
Respons Pengguna Instagram terhadap Periklanan Paid Promote di Instagram dengan Metode CRI Berkonsep AISAS
Authors: Hidayanto Bekti Cahyo , Halim Jessica Patricia , Sari Aura Febriyanti Puspa , Alrifqi Muhammad , Rakhmawati Nur Aini , Akbar Izzat Aulia
Published: May 2022

Instagram is a social media that has a shopping feature. Instagram can be used for digital advertising, and among them is paid promotion. Paid promotion is a service to promote goods/services on social media. This service offers advantages such as a broad market segment, low cost, and easy technical implementation. Many online shops are willing to spend a lot of money to be promoted. Unfortunately, online shop owners usually do not know how Instagram users respond when they see a paid promotion. Therefore, the purpose of this study is to find out how Instagram users respond to the paid promotion on Instagram. User response data was taken from a questionnaire, then analyzed using the CRI method with the AISAS concept by using 4 models: AISAS, AISS, AIAS, and AIS. As the result, four models showed the CRI is below 50% (AISAS: 2,8%; AIAS: 3%; AISS: 4,5%; AIS: 8,4%). Considering the result, the respondents do not give a good response to the paid promotion service.
Perbandingan Forensic Tools pada Instagram Menggunakan Metode NIST
Authors: Irhash Ainur Rafiq  , Imam Riadi  , Herman
Published: May 2022

The development of communication media continues to increase with the emergence of various communication applications on smartphones, which are currently very developed from limited communication media to social media. This change in the flow of communication applications gives a new color to communication, not just exchanging messages and sounds but also exchanging videos and pictures. This development was also followed by the rise of digital crimes in the form of defamation, fraud, and hoax news by spreading posts and then deleting them after the news spread widely. This research was conducted to obtain digital evidence with the help of special applications such as Belkasoft Evidence and Axiom Magnets using the NIST method. The results of this study show that the Magnet Axiom is better with an accuracy rate of 83.3% while Belkasoft Evidence is only 50%.
Guest editorial : Special Guest IASAS Edition: Issues and Challenges in Student Affairs and Services Around the World
Authors: Callahan Kathleen , Mba Chinedu
Published: May 2022

The mission of the International Association of Student Affairs and Services (IASAS) isto serve “as a global advocate for students in higher education, student affairs and services practitioners, and the profession itself” (IASAS, 2017). It seems appropriate that the specialedition of JSAA focuses on issues and challenges in student affairs and services around the world. IASAS was formed from the awareness of and need for a global network for student affairs and services. It was in the mid-90s that the leadership in professional associations and institutions, along with key individuals, began to recognise a need for growth. It was the leadership within IASAS, specifically Roger Ludeman and his colleagues, who pushed for dialogue, connection, and networking around the world. Since its establishment and the recognition of the internationalisation of higher education, we have seen an increase in literature, meetings, presentations, and a general interest in global issues within the field of student affairs and services. Global professional organisations such as IASAS are providing a space for professionals to engage with one another, to share common issues and concerns, and to dialogue with colleagues around the world. Events such as the Global Summits that have taken place over the past few years and other national, regional, and international professional conferences are allowing the sharing of knowledge, ideas, and best practices. Moreover, with journals such as JSAA, the field of student affairs and services is starting to hear more voices ofprofessionals, and learn of both common and new issues and challenges within the fieldaround the world. Due to this growing shift in perspective, this issue highlights a few of those challenges as well as providing reviews of resources available to better our own understandings of student affairs and services around the world, and how we support our students. Authors in this issue as well as scholars are discussing the topic of professionalisation, training ofstudent affairs staff, and the continual emphasis on students. We received submissions fromSouth Africa, Botswana, China, and the USA with a total of five articles and three reviews of seminal works.
Paving the Road to Success: Reflecting Critically on Year One of an Undergraduate Student Support Programme at a large South African university
Authors: De Klerk Danie , Spark Linda , Jones Andrew , Maleswena Tshepiso
Published: May 2022

Student success, faculty and university throughput, and the need for adequate and appropriate student support remain prevalent issues in the South African and global higher education sectors. Subsequently, the Faculty of Commerce, Law, and Management at a large South African university applied forTeaching and Development Grant funding in order to address these areas of concern. The grant was awarded and initially intended to help students at risk by implementing appropriate interventions to prevent them from dropping out of university or being excluded. However, being labelled as “at risk”was not well received by students and so the grant holders designed a new programme, adopting a decidedly more holistic approach. As such, the Road to Success Programme was born. The first three months saw those involved conceptualise, plan, and develop strategies, material, and interventionsthat were implemented in January 2015. The vision was to scaffold and support first-year students, particularly those in danger of being academically excluded, through an integrated network of tutorials, workshops, online support, and a series of resources called Toolkits for Success, in an attempt to help students achieve their academic goals. Despite a number of challenges, ranging from funding shortfallsand food security to students’ emotional wellbeing and resilience, 2015 proved invaluable in terms of refining strategies, gaining insight, and programme growth. Preliminary data shows an increased pass rate for students who engaged with the RSP, with higher pass rates linked to greater RSP attendance. Consequently, this article serves as a critical reflection of the RSP at the end of its inaugural year and will share data, highlight lessons learned and challenges faced, and discuss how the programme has been taken to scale in 2016.
Factors and Problems Contributing to the Burdensome Workload of Architecture Students in Universities
Authors: Hasan Azman Bin , Ibrahim Norzehan Binti , Nordin Mohd Norazmi
Published: May 2022

There is an issue of architecture students in Malaysia public universities burdened with design studio project. A study from a sample of 217 students shows 50 percent are at high levels of burden proving that these architecture students are very burdened with the projects given during the semester while the other 50 percent are at moderate level. Therefore, the study aims to identify factors affecting the burdensome workload of architecture students during their studies and identifying the problems faced by the architecture students during their studies. Researcher used qualitative research approaches based on literature reviews. The information is based on previous studies related to the field of research conducted by the researcher. Based on the research conducted, the researchers concluded that there are 4 main factors contributing to the burden of architecture students in their studies which are the student, lecturers, curriculum and facilities. Meanwhile, the identified problems faced by architecture students throughout their study are time management, cost of living, social relationships and attitudes. Based on the literature review conducted, it is important for the public to know the real situation of architecture students in Malaysia toward improving their mental health and to give a clear picture to the institution about the effects and consequences that the students have to bear if this mental health problem are silenced from public and considered unimportant.
Brand Image Benefits and Halal Destination Loyalty: Are They Truly Linked?
Authors: Lada Suddin , Gazali Haneffa Muchlis , Samsulbahri Mohd Nasir , Rahman Rahida Abd. , Jalil Mohamad Isa Abdul , Amboala Tamrin
Published: May 2022

The HALAL tourism is flourishing in its own right as an industry, where Malaysia is the world's leading Halal industry with Halal tourism destination making a significant contribution to overall economic growth. However, to secure this reputable image Malaysia has to build a strong brand image groundwork for future sustainability. By obtaining a combination of brand image benefits and destination loyalty model, this study, therefore, aims to examine whether there is a significant relationship between brand image benefits (i.e. symbolic, functional, social, and experiential benefits) and destination loyalty among tourists visiting Malaysia as a brand of Halal tourism destination. A self-administered questionnaire was used to gather information from 300 selected respondents and analyzed it using Smart PLS. Results revealed that symbolic, functional, and experiential benefits have a significant relationship with destination loyalty among tourists visiting Malaysia. The theoretical and practical implications of the results are discussed and the future improvement of the research is suggested.
Manufacture of Thermal Building Insulators from Waste Cigarette Butts
Authors: Sabah Sahar , Bdaiwi Waleed
Published: May 2022

Waste cigarette butts fiber (CBS) was used and recycled by reinforcing it with unsaturated polyester resin (UPE). It was used to obtain structural sections at a low cost and eliminate the environmental pollution risks resulting from these wastes (CBS). Samples were prepared by manual casting according to the mass fractions (0%, 2%, 4%, 6%, 8%, 10%) of cigarette butt fibers (CBS). The prepared samples carried out mechanical tests (hardness, bending, and tensile elastic modulus). The results showed that the modulus of elasticity and bending resistance increased with the increase of the weight ratio and that these values were directly proportional to the increase in the amount of reinforcement from the CBS fibers.
A Novel Noise Removal Technique for ECG Enhancement: A Comparative Analysis
Authors: Balasubramanian S. , Naruka Dr. Mahaveer Singh
Published: May 2022

The Electro Cardiogram (ECG) is most generally used for the identification and conclusion of heart illnesses. Great quality ECGs are used by doctors for understanding and identifying physiological and neurotic peculiarities. Nonetheless, in real circumstances, ECG signals are undermined by the corruption of artifcats. Though the LMS algorithm is mostly used for the removal of noise to enhance ECG, some issues persist such as the higher input data vector. So, to overcome such limitations, a logarithmic adaptive filtering technique is been used for ECG enhancement. Logarithmic algorithms incorporate the lower and higher order values of the error into a single continuous updating equation since they are dependent on the error amount. This result in the surge of convergence rate in logarithmic adaptive algorithms similar to the LMLS algorithm and reduces the complexity of computations in a conventional LMS algorithm. Experiment results are performed over various state-of-art models in the literature review under various measures and the proposed model outperforms effectively.
Navigating a triple challenge: linguistic, academic, and sociocultural
integration of students in refugee-like situations
Authors: Morel-Lab Anne
Published: May 2022

According to the Agence Universitaire de la Francophonie (AUF), since
2016 many French universities have set up French language teaching
programmes for refugees and people with subsidiary protection to respond to
their need of linguistic support in French before starting or resuming their
higher education studies. Welcoming such students however requires taking
into consideration a wide range of complex situations for which the French
higher education system is not designed. The universities concerned have
therefore to face the same issue: what kind of programme can be set up to
support the integration of such students and respond to their linguistic
insecurity without altering standards? In 2017, the AUF launched AIMES
(Accueil et Intégration des Migrants dans l’Enseignement Supérieur), a
programme initiated to support universities willing to develop the
appropriate learning structures needed to obtain the accreditation for the
University Diploma Passerelle (DU Passerelle), an integrated university
diploma aiming to enable students with an atypical background to acquire a
B2 level in French, B2 being the language level required to continue their
studies at a French university. In this chapter, I will first introduce the
CIEF (Centre International d’Études Françaises) of the University of Lyon 2
which is one the language centres involved in this programme. I will then
present the CIEF curriculum for the DU Passerelle and finally, develop the
teaching methods set in place to respond to the specific needs of the
students in refugee-like situations, introducing the notions of glottophobia
and bientraitance linguistique as theoretical tools helping to analyse their
linguistic environment.
Language education as public engagement: designing authentic projects on
German-speaking film
Authors: Jochum-Critchley Thomas
Published: May 2022

This chapter argues for the integration of public engagement into
language teaching in order to respond to the current challenging environment
for language study. Impact teaching seeks to develop language education
through engagement with audiences beyond the classroom and especially
outside higher education. One illustration of this approach is the student
projects which have been designed as part of the module ‘Contemporary
German-speaking film’, first introduced at the University of York in
2018/2019. The project brief asks students to organise, prepare, and deliver
a film evening event including a film introduction and a post-screening
Q&A in German. The approach has proven very successful with very
positive student feedback on the initial in-person format, despite the
limited audience numbers. The move to an online format during the pandemic
has increased the impact of the event dramatically and the newly collected
attendee feedback has confirmed very positive responses to the
projects.
How Covid-19 has changed language assessments in higher education: a
practitioners’ view
Authors: Polisca Elena , Stollhans Sascha , Bardot Romain , Rollet Cyrille
Published: May 2022

This chapter examines the responses of Higher Education Institutions
(HEIs) to assessment-related challenges introduced by the Covid-19 pandemic.
The sudden move to online teaching and assessments required institutions to
re-think their approaches to current practices and provide alternative
solutions almost overnight. Our survey aimed to gather the perceptions of
language teaching practitioners on how the languages sector dealt with the
move to digital assessments, with particular emphasis on the delivery of
online assessments, the impact on different language skills, as well as
academic integrity. Results show that, whilst different institutions adopted
varying practices, they seem to share similar concerns in addressing the
fast-changing environment and ensure that academic integrity remains at the
forefront in the move to the digital world.