bluuebunny/crossref_metadata_2025 huggingface dataset:
مدينة أبذة الأندلسية 92-630 هـ / 710-1232م
Authors: الدرويش الأستاذ الدكتور جاسم , العلياوي الأستاذ الدكتور حسين
Published: August 2023

تقع مدينة أبثا في المنطقة الوسطى من الأندلس. وهو أحد أعمال كورا جيان وعلى الوادي الكبير شرق قرطبة. فتحها المسلمون سنة 92هـ/710م، واستوطنتها قبيلة بني يعمر العربية الشامية. واستمر الحكم الإسلامي أكثر من خمسة قرون. شهدت المدينة أحداثاً مهمة منها ثورة ابن حفصون، وكانت المدينة مسرحاً لأحداثها حوالي ثلاثين عاماً، ومنذ القرن السادس/12م أصبحت المنطقة حدوداً غنية وتعرضت للعديد من الهجمات من قبل ومهد المسيحيون الطريق للقبض على العديد من الثورات مثل ثورة بني مردانيش وابن همشك وأخيرا حركة بياسي الموحدي التي ضمت إلى سلطته مما أضعف قوة المسلمين وسهل سقوطها بعد أن أبادوها. الناس.
أمريكا في الشعر الفلسطيني الحديث (الصور التشبيهية انموذجا)
Authors: عزيزي الأستاذ المساعد الدكتور نعمت , نظري الأستاذ الدكتورعلي , الحسيني الأستاذ المشارك الدكتور سيد محمود
Published: August 2023

يُعدّ التشبيه أحد موضوعات النقد العربي القديم، حيث قُدّمت آراء مختلفة حول عناصره. ويُعتبر التشبيه من أهم الأدوات والأساليب التي حاول الشعراء من خلالها التعبير عن آرائهم ومشاعرهم تجاه العالم المحيط بهم. تُعدّ الصورة السياسية للولايات المتحدة الأمريكية من الموضوعات التي تحولت إلى قضية رئيسية في الشعر الفلسطيني. وبالنظر إلى سياسات الولايات المتحدة ودورها في أحداث القرون الماضية، ومواقفها العدائية وتدخلها في شؤون الدول، ولا سيما فلسطين المحتلة، فقد أصبح هذا الموضوع واحدًا من أهم القضايا التي تناولها الشعراء الفلسطينيون، حيث صوّروا الولايات المتحدة بطرق مختلفة.  
ويُعدّ التشبيه من أبرز الأساليب والتقنيات التي استخدمها الشعراء الفلسطينيون لتجسيد المواقف الأمريكية وجرائمها ضد الدول الأخرى، بما في ذلك العراق، وفيتنام، وفلسطين المحتلة، وغيرها. تسعى هذه الدراسة إلى الكشف عن الصورة الحقيقية للولايات المتحدة، ومواقفها، وسياساتها، كما تم تقديمها في الصور المجازية التي استخدمها الشعراء الفلسطينيون المعاصرون، ومنهم: سميح القاسم، معين بسيسو، برهان الدين البوشي، وصالح فروانة، وغيرهم. ومن بين النتائج الجوهرية التي توصلت إليها هذه الدراسة، والتي تم تحقيقها من خلال المنهج الوصفي-التحليلي، أن الشعراء الفلسطينيين قد شبّهوا الولايات المتحدة بوحشية الذئب، وفساد الشر، وإغواء الشيطان.
الخصائص المناخية وعلاقتها بالخصائص النوعية لمياه نهر الديوانية*
Authors: الجصاني الاستاذ الدكتور نسرين , الجنة هبة
Published: August 2023

يهتم البحث بدراسة وتحليل علاقة الخصائص المناخية بنوعية مياه نهر الديوانية حيث تتميز هذه الخصائص المناخية بدرجات الحرارة وسرعة الرياح وهطول الأمطار والعواصف الترابية خلال الفترة 15 – 15 . شملت المياه درجة الحرارة والأكسجين الذائب ودرجة الحموضة والعدد الكلي للبكتيريا الحية.  تم أخذ العينات وجمعها من المياه وكانت هذه العينات من ثمانية مواقع ( عينات من كل موقع)، تم جمع العينة الأولى في شهر أغسطس لتمثل فصل الصيف، وتم جمع العينة الثانية في شهر أكتوبر لتمثل فصل الخريف، وتم جمع العينة الثالثة في شهر يناير لتمثل فصل الشتاء وتم جمع العينة الرابعة في شهر إبريل لتمثل فصل الربيع. يتضمن البحث دراسة العلاقة الاحصائية بين الخصائص المناخية وخصائص نوعية مياه نهر الديوانية بالاعتماد على الطرق الاحصائية مثل معامل الارتباط ومعامل الانحدار واختبار T ومعامل التحديد. أظهرت النتائج تبايناً واسعاً في خصائص المياه تبعاً لخصائص المناخ كمعامل ارتباط الشخص ومعامل الانحدار (P˂.).ارتباط سلبي وكامل بين درجة الحرارة والأكسجين الذائب في الماء (-.) مع R (. ).كما أظهرت النتائج أن الخصائص المناخية ترتبط ارتباطاً وثيقاً ببعض خصائص نوعية المياه مما يدعم فرضيات الباحث فيما يتعلق بعلاقة الخصائص المناخية بنوعية المياه.
Consumer Awareness on Food Adulteration Practices on the Market and its Challenges
Authors: Amoah Millicent , Adonu Regina Enyonam , Opoku Hannah , Atiemoh Mercy Gyamea
Published: August 2023

Food adulteration has been a problem since the dawn of civilization because it not only lowers the quality of food but also has various negative health impacts. Value evaluation and ensuring consumer protection from fraudulent activities both involve authentic testing of food and adulteration detection of various food products. This study examined consumer’s awareness of food adulteration practices on the market and its challenges. The study sampled 240 shoppers at the Takoradi main in Ghana. The study revealed that though food adulteration has received a lot of media attention, most consumers still lacked a lot of knowledge on what constitutes an adulterant and how to detect it at the household level. Various adulteration practices such as poor handling and packaging of fresh products, excessive use of artificial flavouring and colouring substances, misuse of food additives among others were found to be very common on the market. Challenges of food adulteration such as the lack of adequate technology to detect adulterants in food as well as consumers awareness of procedures to lodge complaints pertaining adulteration were also found. Consumers and food regulatory agencies were hence admonished to ensure that the necessary protocols are followed whenever issues concerning food adulteration occurs.
Type of School as a Socioeconomic Indicator and its Impact on the Nutritional Status, School Performance, Self-Esteem of Basic School Students (10-12 Years Old) in Khartoum Locality, 2014
Authors: Ahmed Braa , Magboul Bahieldin I
Published: August 2023

Adolescence, a critical phase of rapid physical, social, and psychological growth, encompasses individuals aged 10 to 19 years, Evaluating nutritional status for decades has involved standard methods like dietary, anthropometric, biochemical tests, and clinical signs, often incorporating socioeconomic status (SES) as a key determinant. The study aimed to assess the nutritional status of students (10-12 years old) attending three types of basic schools whose families’ SES was categorized according to school fees paid as high, medium and low. Methodology: This cross-sectional community-based study investigated the influence of family socioeconomic status (SES) on the nutritional status, school performance, and self-esteem of children aged 10-12 years attending basic schools 2014. 210 participants were chosen. Data were collected through anthropometric measurements and a questionnaire covering demography, dietary patterns, self-esteem assessments, and school performance obtained from schools. Statistical package for social sciences version 26 used for analysis. Result: Data from 210 students (45.2% boys, 54.8% girls) The findings revealed a significant impact of family SES (P=000) on nutritional status, energy and protein intake, school performance, and self-esteem. Low SES families had a higher prevalence of underweight children (66.7%), while high SES families had more overweight and obese children. Those from high SES consumed more animal foods, fast foods, fresh fruits, and vegetables compared to medium and low SES groups. High school grades were predominantly achieved by high and medium SES students, with low SES students obtaining lower grades. Normal-weight students exhibited better school performance and self-esteem than overweight, obese, and underweight students. In conclusion, family SES significantly influenced the nutritional status, school performance, and self-esteem of children attending basic schools. Recommendations, to ensure students' well-being, ..
Has the COVID-19 Pandemic Affected Homeless Patients Visiting the Emergency Department?
Authors: Ilhan Pelin , Sarıdaş Ali , Trabzon Seyma , Olt Meryem Cansu , Sert Havva
Published: August 2023

Objective: Our aim was to compare emergency department visits among homeless patients before and during the COVID-19 pandemic.
Material and Methods: We retrospectively examined data from homeless patients who visited a city hospital's emergency department in Istanbul between March 11, 2018, and March 10, 2022. The study included patients over 18 years old who were registered in the hospital's automation system as "homeless" or "living on the street," and who had sought social service support. Descriptive statistics, Student's t-test, Mann-Whitney U test, chi-squared test, Fisher's exact chi-squared test, Fisher-Freeman-Halton exact chi-squared test, and Yates continuity correction test were utilized for data analysis.
Results: The study encompassed a total of 105 homeless patients, with 85 (81%) being male and aged between 18 and 88 years. The mean age was 44.54±16.25 years. Of the patients, 21.9% visited the emergency department before the pandemic, and 78.1% visited during the pandemic. Among homeless patients suspected of COVID-19, 20% who visited the emergency department tested positive for the polymerase chain reaction (PCR) test.
Conclusion: Our findings indicate an increase in the number of homeless patients seeking care in the emergency department during the COVID-19 pandemic
Evaluation of Brain Perfusion with Radionuclide Imaging in Dementia Patients
Authors: Ceylan Sule
Published: August 2023

Objective: This study aims to evaluate the perfusion in the affected brain lobes with radionuclide imaging in patients with dementia and to contribute to the literature by determining the relationship between the degree of dementia.
Methods: In this retrospective study, 44 adult patients were included. The mean age of the patients was 73 (57-87). Twenty-three (52.3%) of these were female. All patients underwent mini-mental state test, neurological examinations and radionuclide brain perfusion imaging. The areas of interest of the frontal, parietal, temporal, and occipital lobes and the cerebellum were drawn, respectively, and the cerebellum ratios of the relevant lobes were compared. In this way, brain perfusion index values of lobes were obtained.
Results: Brain perfusion in group 1 was higher than in other groups. Groups were also compared in pairs. There was no significant difference in perfusion values in the occipital lobe. There was a significant difference in perfusion between groups 1 and 2 in lobes other than the occipital lobe. This was also the case for Groups 1 and 3. When group 2 with early dementia symptoms, and group 3 with moderate dementia were compared, there was a significant difference between the perfusion values of only the right and left frontal lobes.
Conclusion: Early diagnosis is very important in progressive dementia. Clinical tests are successfully applied to categorize patients. Evaluation of brain perfusion and metabolism with functional radionuclide imaging is significant in guiding the treatment and evaluating the success of the treatment.
What is the tolerance age of patients with cow's milk protein allergy? What are the parameters that can predict its persistence?
Authors: Atakul Gizem , Al Serdar , Atay Özge , Kangallı Boyacıoğlu Özge , Asilsoy Suna , Uzuner Nevin
Published: August 2023

Objective: Cow’s milk allergy (CMA) is one of the most common food allergies in infants. The natural history of CMA indicates that resolution is common. Some studies suggest that food allergies are now being resolved at an older age. The aim of this study was to investigate the tolerance and persistence characteristics, as well as the timing of tolerance, in our own CMA patients.
Material and Methods: Patients who were diagnosed with CMA and followed up in our pediatric immunology and allergy outpatient clinic between 2016-2021 years were evaluated retrospectively. Patients’ demographic characteristics, laboratory results, and tolerance time were recorded.
Results: The 632 patients’ files were reviewed. 192 (30%) of the patients were followed for more than two years. The tolerance to baked products was observed with a median of 14 months, while the tolerance to fermented products was observed with a median of 17 months. Full tolerance was observed with a median of 25 months. The number of patients older than 2 years of age who could not consume any milk protein-containing product was 72 (11.4%) and 56 (77.7%) of them were IgE mediated CMA. The rate of girls with tolerance (43.5%) was found to be significantly higher than nontolerant girls (25%) (p=0.001). The mean skin test diameter of the tolerant group was significantly higher than the mean of the non-tolerant group (p=0.022). The percentage of eosinophils (p=0.003) and total IgE level (p=0.004) in the tolerant group were significantly lower compared to the intolerant group. There was no significant difference between the presence of tolerance in terms of allergy number, eosinophil count and specific IgE count (p>0.05).
Conclusion: Identifying the factors influencing tolerance can lead to changes in the management of the disease. We observed that 88.6% of patients older than 2 years were tolerant to milk proteins, and all patients with non-IgE mediated CMA achieved tolerance by 2 years of age. The ratio of total IgE to specific IgE, age, total IgE and specific IgE levels, presence of non-IgE or IgE mediated allergy, and gender were factors that influenced the development of tolerance in our study. Age at diagnosis and having a single or multiple food allergies did not impact the tolerance status. The prognosis for CMA remains favorable. The use of the milk ladder in managing CMA is an important approach for promoting early tolerance.
Tratamiento de meduloblastomas en infantes
Authors: San Martín García Diego , Bennett Colomer Carlos
Published: August 2023

El meduloblastoma es el tumor cerebral maligno más común de la infancia. El tratamiento convencional del meduloblastoma involucra resección máxima segura, quimioterapia y radiación craneoespinal en niños mayores de 3 años. En menores de 3 años, los efectos de la radioterapia de neuroeje son prohibitivos en cuanto al desarrollo de trastornos neurocognitivos, por lo que habitualmente es omitida en este grupo etario. La omisión de radioterapia se asocia a un peor pronóstico oncológico, mayores tasas de recidiva local y a distancia. Esto ha motivado a explorar múltiples alternativas de tratamiento en este grupo etario. Planteamos un estudio retrospectivo en el cual analizamos pacientes de 0 a 4 años diagnosticados de meduloblastoma tratados en nuestro centro desde 2000 a 2022. Once casos, 5 menores de 3 años. Obtuvimos una sobrevida global a 1 año del 72,7%, a 3 años del 27,2% y a 5 años del 27,2%. La mediana de sobrevida de los pacientes de 3 años o menores fue de 13 meses. La mediana de sobrevida de los mayores de 3 años fue de 32,5 meses. La mediana de sobrevida en pacientes que recibieron radioterapia, independiente del grupo etario, fue de 50,5 meses. Los resultados obtenidos siguiendo el protocolo PINDA, ha entregado resultados similares a los publicados en el protocolo Baby Pog, lo que a la luz de las publicaciones más modernas entrega tasas de sobrevida que parecen ser insuficientes, lo que desafía a incorporar nuevas estrategias de tratamiento más específicas para cada caso.
ВЛИЯНИЕ ХРОНИЧЕСКОГО КУРЕНИЯ НА ЛИПИДНЫЙ ПРОФИЛЬ
Authors: Музакаева Х.С. , Дускаев М.З.
Published: August 2023

Во всем мире развивается эпидемия сердечно-сосудистых заболеваний, наиболее частой причиной которых является атеросклероз. Курение сигарет остается важнейшей причиной заболеваемости и ранней смертности. Никотин вызывает сильное привыкание, он повышает уровень дофамина в мозгу и вызывает симптомы отмены при прекращении употребления.
СИСТЕМАТИЗАЦИЯ ВИДОВ И КОЛИЧЕСТВА ЯДОВИТЫХ РАСТЕНИЙ НА ТЕРРИТОРИИ ЧЕЧЕНСКОЙ РЕСПУБЛИКИ
Authors: Мезиева С.К. , Умаева А.М.
Published: August 2023

В данной статье проведен систематический анализ всех ядовитых растений, произрастающих на территории Чеченской республики, проведена их классификация по семействам. Также проведена классификация по родам. Представлена визуализация собранной информации в виде графиков.
АНАЛИЗ ВЛИЯНИЯ КИСЛОРОДА НА МИКРОМИЦЕТЫ
Authors: Дохтукаева А.М. , Лорсаева Р.Ш. , Магомадова М.А.
Published: August 2023

Содержание кислорода в природных средах значительно изменяется в зависимости от их специфики, при этом значительную роль в формировании концентрации этого элемента играют именно микроорганизмы. В тропосфере планеты концентрация кислорода колеблется от 16 до 21%. Поскольку в воде кислород растворяется слабо, особенно при росте температуры и уровня концентрации солей, составляя около 8 мг/л при 20°С, то вода считается природной средой с низким уровнем аэробности. Чем больше в среде обитания содержится разлагаемых органических веществ, тем быстрее имеющаяся концентрация кислорода используется аэробами, разлагающими их, потребляется другими микроаэрофилами, делая содержание О2 лимитирующим фактором этого местообитания. В ряде водно-донных компонентов, например, в иле, кислород способен находиться в широких пределах изменения концентрации, создавая резкие градиенты, включая полное исчерпание О2. Такие же перепады концентраций кислорода отмечаются в почвенных ценозах, где в одном почвенном агрегате могут отмечаться как аэробные, так и полностью анаэробные микрозоны.
STUDY OF IMMUNE-INFLAMMATORY RESPONSE CHANGES IN ORAL FLUID IN PATIENTS WITH DISEASES OF PERIODONTAL TISSUES IN COMBINATION WITH GENERAL SOMATIC PATHOLOGY
Authors: Shevchuk Maryana , Shkrebnyuk Roksolana , Dyryk Volodimira , Mrochko Oleg
Published: August 2023

The aim: To determine the concentration of markers of the immune-inflammatory response (IL-1β, IL-10, IL-1β / IL-10, hsCRP) in oral fluid in patients with diseases of periodontal tissues in combination with general somatic pathology.
Materials and methods: The study was conducted at Danylo Halytsky Lviv National Medical University, Department of therapeutic dentistry FPGE, Lviv, Ukraine. The patients were divided into two groups: the main group – 144 patients (with periodontal tissue diseases on the background of general somatic pathology) and the control group – 30 somatically and dentally healthy persons, in whose oral fluid was determined the concentration of IL-1β, IL-10, hsCRP by the enzyme immunoassay method.
Results: As a result of our research, it was found that in people with periodontal tissue diseases, against the background of general somatic pathology, there is an activation of the immune-inflammatory response, which aggravates the course of general somatic and dental diseases in this contingent of patients.
Conclusions: Therefore, in patients with periodontal tissue diseases on the background of somatic diseases, a significant increase in the level of the pro-in¬flammatory cytokine IL-1β and hsCRP was determined against the background of a decrease in the anti-inflammatory cytokine IL-10 in the oral fluid compared to the values in the control group.
PECULIARITIES OF FORMATION OF CARBOHYDRATE METABOLISM DISORDERS WITH COMORBID CHRONIC PANCREATITIS AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Authors: Dudka Inna , Khukhlina Oksana , Dudka Tetiana , Voyevidka Oksana , Roshchuk Oleksandra
Published: August 2023

The aim: To determine glycemic condition, regulation of carbohydrate metabolism, degree of insulin resistance in patients with chronic pancreatitis with its isolated course and with comorbid COPD and diabetes mellitus.
Materials and methods: 110 patients with chronic pancreatitis were examined. The first group of patients included 38 individuals with an isolated course of chronic pancreatitis (1 group), 2nd group included 35 patients with chronic pancreatitis and COPD, 3rd group included 37 patients with chronic pancreatitis and COPD and type 3c diabetes mellitus. The control group (CCOPD) included 32 individuals with isolated COPD, the control group (CDM) includes 34 individuals with isolated type 2 diabetes mellitus. All the patients were examined for functional state of the pancreas and carbohydrate metabolism was assessed.
Results: Patients suffering from chronic pancreatitis with COPD and diabetes mellitus developed 3.2 times increased glucose concentration on an empty stomach. Blood glucagon content in all patients was lower in comparison with that of practically healthy individuals which is indicative of an insufficient glucagon secretion by α-cells of the pancreas. Pancreatic polypeptide content in the blood was lower in patients with chronic pancreatitis and COPD and T3c diabetes mellitus in comparison with the reference value.
Conclusions: A comorbid course of chronic pancreatitis with exacerbated COPD is associated with more intensive disturbances in carbohydrate metabolism regulation and glycaemia parameters in comparison with an isolated course of chronic pancreatitis. In case comorbidity includes a chronic pancreatitis, chronic obstructive pulmonary disease and diabetes mellitus, the most unfavorable glycemic profile is found which is indicative of carbohydrate metabolism decompensation.
ASSESSMENT OF CARDIOPROTECTIVE EFFECT OF NECROSTATIN-1 STABLE IN A MICE MODEL OF ACUTE DOXORUBICIN-INDUCED CARDIOTOXICITY
Authors: Abbas Shaymaa Fadhil , Abdulkadim Hussein , Al-Hashemi Hind A. , Hadi Najah Rayish
Published: August 2023

The aim: To evaluate the effect of Necrostatin-1s (Nec-1s), an inhibitor of necroptosis, on acute Dox-induced cardiotoxicity in a mice model.
Materials and methods: Fifteen male mice were used. The animals were allocated into three groups. On the third day of the experiment, a single intraper¬itoneal dose of 20 mg/kg Dox was used to induce cardiotoxicity. Mice in the control group were given vehicle (DMSO) intraperitoneally, whereas mice in the third group were given 5 mg/kg Nec-1s two days before Dox treatment and continued for a total of five days. Animals were euthanized at the conclusion of the research. ELISA was used to assess the following parameters: cTnI, TNF-α, IL-1β, GPX-4, and Hmox-1. The expression of TNF-R1 and phosphorylated NF-κβ p65 was measured using immunohistochemistry. In addition, a histopathologic evaluation of the cardiac lesions was conducted.
Results: Our results showed that Dox treatment substantially elevated serum cTnI levels, increased tissue inflammatory biomarkers (TNF-α, IL-1β, phospho NF-κβ p65 and TNF-R1), and reduced tissue antioxidant enzymes (GPX-4, Hmox-1). A histopathological analysis showed pronounced necrosis and vacuolization. These results were drastically changed by pretreatment with Nec-1s, with serum cTnI levels in this group being much lower than in the Dox group. In addition to a significant decrease in inflammatory markers, antioxidant enzymes were partially recovered. Moreover, there was preservation of the cardiac morphology to a level that was roughly normal.
Conclusions: Our findings demonstrate that pretreatment with Nec-1s protected against acute Dox-induced cardiotoxicity. This cardioprotective effect was mainly due to amelioration of inflammation that reflected by inhibition of NF-κβ/TNF-α/TNF-R1 pathway, with partial restoration of antioxidant enzymes, GPX-4 and Hmox1.
EVALUATION OF D-DIMER LEVEL AS A BIOMARKER OF DISEASE SEVERITY AND MORTALITY IN PATIENTS WITH COVID-19
Authors: Kolotylo Tetiana R. , Moskaliuk Vasyl D. , Syrota Borys V. , Balaniuk Iryna V. , Melenko Svitlana R. , Chernetska Natalia V. , Boiko Yuliia I.
Published: August 2023

The aim: To examine risk factors and evaluate the use of D-dimer as a biomarker of disease severity and mortality in patients with COVID-19.
Materials and methods: Data from a large NYU Langone Health system were analyzed to examine the prevalence of elevated D-dimer levels at first detection and the trend. A retrospective cohort study of 2,377 patients (NYU Langone Health) with severe COVID-19. Also we conducted a retrospective study based on the mortality database of 247 patients from COVID-19 at the Chernivtsi Regional Clinical Hospital.
Results: Patients with elevated baseline D-dimer were more likely to have critical illness than patients with normal D-dimer (43.9% vs. 18.5%).
The frequency of adverse events increased with increasing D-dimer levels. Individuals with D-dimer >2000 ng/mL had the highest risk of critical illness (66.0%).
Conclusions: Thus, the level of D-dimer can be considered an important prognostic factor in COVID-19, as its level is elevated in the vast majority of patients with COVID-19 and correlates with a severe course and high mortality.
ACCUMULATION OF HEAVY METALS IN THE COLON AND BLOOD OF PATIENTS WITH COLORECTAL CANCER
Authors: Tataryn Bohdan , Kryzhanivska Anna , Andriiv Alina , Riznychuk Nadiya , Horoshko Svetlana , Graf Еugene , Tataryn Lilia
Published: August 2023

The aim: To determine the accumulation of heavy metals, namely Cr, Cd, Cu, Pb, Zn by a tumour in correlation with unaffected colon tissue and blood of patients with colorectal cancer.
Materials and methods: The study is based on the results of observation of 180 patients with CRC. The following samples were taken from: the tumor, the colon and blood unaffected by the tumor – during the operative treatment of patients in the surgical department of the communal non-profit enterprise “Precarpathian Clinical Oncology Center of the Ivano-Frankivsk regional council” for 2018-2020.
Results: According to the obtained results, the blood of patients with CRC contains much less heavy metals: Pb – 8.6 and 9.3 times less than in the tumour and unaffected by cancer colon, respectively; Cr – 9 and 14.8 times less; Cd – 3.75 and 5 times less; Cu – 1.48 and 1.18 times less than in the tumour and unaffected colon, respectively. Besides, the content of Zn in the blood is 1.04 times higher than in non-cancerous tissue of the colon.
Conclusions: It can be stated that the highest content of Pb, Cr and Cd was recorded in non-cancerous tissue of the colon of patients with CRC; the highest content of Zn and Cu was revealed tumour tissue.
ANALYSIS OF THE RESULTS OF A MEDICAL AND SOCIOLOGICAL SURVEY OF HEALTHCARE PROVIDERS ON MOTIVATIONAL COMPONENT OF ENSURING THE HEALTHCARE QUALITY
Authors: Loboda Andrii M. , Oleshko Oleksandr M. , Pryimenko Oleksandr S. , Raian Shtainberher , Hlushchenko Victoria V.
Published: August 2023

The aim: To identify the main motivational components of improving the healthcare quality in health care providers in Sumy.
Materials and methods: The study involved data obtained from 187 doctors working in primary health care institutions, inpatient and outpatient departments of health care institutions in Sumy, during September-November 2020. The study used systematic, bibliosemantic approaches, comparative and statistical analysis, and logical generalization. The obtained data were processed and statistically analyzed with Google Forms and Microsoft Excel 2010 Windows.
Results: The analysis of data received from the surveyed group of respondents showed that 83 doctors (44.39%) have 11-15 years’ work experience, 51 people (27.27%) – 6-10 years, 40 people (21.39%) have up to 5 years of work experience and 13 people (6.95%) – more than 15 years. Most doctors (114 people (60.96%)) work for one position, 39 people (20.86%) work for less than one, while 34 people (18.18%) work for more than one position. The number of doctors who indicated that they were mostly overworked during the working day was 123 (65.77%), another 46 (24.60%) indicated that they were overworked during the working day correspondingly to their workload at occupied position, and 18 respondents (9.63%) answered that they were not fully loaded. At the same time, 91.98% of people indicated that the actual amount of their salary does not correspond to the workload, and there is no financial stimulation system for medical care quality increasing (87.70% of responses).
Conclusions: The study showed that the healthcare facilities where the respondents work do not have an effective system of staff motivation for work quality (79.14% of responses). It was found that doctors are ready to work harder and better for additional pay, despite the high level of workload (88.24% of responses), and consider it necessary to introduce an effective stimulation system to improve the quality of medical services (96.79% of responses).
THE PROBLEMS OF CRIMINAL LIABILITY OF PHARMACEUTICAL EMPLOYEES IN THE CONTEXT OF CERTAIN FORMS OF COLLABORATIVE ACTIVITIES
Authors: Berzin Pavlo , Demchenko Ivan , Berzina Anzhela
Published: August 2023

The aim: Based on the specifics of the criminal legislation, which provides liability for collaborative activity, it is necessary to offer an adequate understanding of the limits of the criminal liability of pharmaceutical employees for these criminal offenses, as well as to determine the characteristics of the components of these criminal offenses related to the pharmaceutical activities carried out by pharmaceutical employees.
Materials and methods: The conducted research is based on the analysis of the provisions of the criminal legislation of Ukraine and Georgia.
Conclusions: The main problems of criminal liability for collaboration activities by pharmaceutical employees are connected to the following: without clari¬fication of the aforementioned criminal offenses, it is impossible to specify the limits of criminal liability.
Improving the LVRT Capability of the DFIG- Based Wind Turbines during Fault
Authors: - Priya Manohar Ingle
Published: August 2023

According to the coordination control of a dynamic voltage restorer (DVR) and an inductive fault current limiter (FCL), this paper proposes an efficient low-voltage ride-through (LVRT) scheme for a doubly fed induction generator (DFIG) based wind turbine. The DVR is located to the DFIG’s stator circuit for stabilizing the terminal voltage and decreasing the generator current. The inductive FCL is connected to the DFIG’s rotor circuit for suppressing the rotor overcurrent and protecting the converter. Theoretical discussions on structure, principle and scale criterion of the combined DVR-FCL are conducted, and simulation analyses of the proposed approach to handle symmetrical and asymmetrical faults are done in MATLAB/Simulink. In this study, the dynamic characteristics of the DFIG during the faults are analyzed from multiple aspects, and a detailed comparison of the proposed approach and the single action of DVR or FCL is carried out. From the simulation results, the effectiveness and superiority of the proposed approach are well demonstrated.
Historical Interpretation of the Phenomenon of Indian Renaissance
Authors: - SARASWATI KUMARI
Published: August 2023

This paper is all about the historical interpretation of the phenomenon of Renaissance in context to India.It discusses about the various perceptions being thought about the renaissance in India.How it was historically being analyzed as mere imitation of the west and later on perceived as the impact of the intellectual enlightenment of the Indian mind and not the imitator of the west. this paper also throws light on how the British conquest and the consequent dissemination of colonial culture and ideology had led to an inevitable introspection about the strengths and weaknesses of indigenous culture and institutions.The response to it was varied but the need to reform social and religious life was a commonly shared conviction. This paper also discusses about how the European renaissance led to the accomplishment of the western culture that was not Indian but had a great influence on Indian mind.it also discusses a perceived thought about how depressed culture in a European context was a tragedy of Indian intellectualism also.
Social Media Advertising: A Study of Consumer Demographics
Authors: - Madhuri  Yadav
Published: August 2023

Social media has grown into an essential platform for businesses to engage with and make an impression on their target market. Since the advent of digital platforms, marketers have focused on researching the effectiveness of advertisements and the best channels for sharing them. The study focuses on how well-informed people are about social media advertising and how it influences consumer demographic profiles, consumer trust in selected social media advertisements, and the reliability of social media advertisements. Numerous social networking sites, including Facebook, Twitter, YouTube, Instagram, etc., use various communication strategies that not only have an effect on their members but also help in appealing to them to interact. Instead of the usual banner and pop-up advertising, people become emotionally attached to brand communication on social networking sites. The study is based on both secondary and primary data. Using a questionnaire and the random sampling technique, data was gathered from 180 respondents within various districts of Uttar Pradesh.
National Education Policy 2020 and Higher Education: A Comprehensive Analysis of Impact, Challenges and Opportunities
Authors: - UMAYA FAROOQ
Published: August 2023

The educational system forms the bedrock of a nation's progress and advancement. The National Education Policy 2020 has been reimagined as the cornerstone of this transformation, holding the potential to revamp the country's educational system and enhance its economic and social indicators. Recognizing education's role in driving societal and economic progress, a well-defined and forward-looking educational strategy is imperative for a nation's schools and colleges. Various countries adopt diverse educational frameworks, influenced by their traditions and cultures, all aimed at benefiting individuals at different stages of their academic journey, particularly in high school and college. Recently, the Indian government introduced a fresh educational blueprint, drawing from recommendations by a panel of experts. The proposed changes brought about by NEP 2020 have caught many educators off guard. While both secondary and tertiary education have felt the impact of this policy, this article primarily centers on NEP 2020 and its implications for higher education. The primary focus of this paper revolves around NEP 2020 and how it shapes higher education. The document also highlights the key aspects of NEP and examines the prospects and obstacles tied to the implementation of NEP 2020 within higher education institutions.
Charaterizing Payment Default of Low-Cost Housing Loans
Authors: - Devine Grace R. Mutia , - Vicente Salvador E. Montaño
Published: August 2023

This study aimed to develop a framework on factors affecting payment default in low-cost housing loans. A total of 462 low-cost housing loan borrowers have participated in the study. Adapted-modified research questionnaire and stratified random sampling technique were employed to gather data from participants. The Exploratory Factor Analysis, Frequency Distribution and Binary Logistic Regression analysis were utilized as statistical tools to analyze the data. It revealed that there were five factors that characterized payment default of low-cost housing loans namely, Loan Effects and Liquidity, Loan Monitoring, Quality or Level of Account Management, Saving Attitude, and Loan Sufficiency/Adequacy. Further, 60 percent of the borrowers are paying their loans on time, meanwhile, 40 percent were paying their loan or before the due date. Using binary logistic regression, the study concluded that loan effects and liquidity (0.005 < 0.05), and saving attitude (0.000 < 0.05), were found to significantly influence the payment default of borrowers.
An Investigation into the Perspective of D.EL.ED Trainees at Diets in Tripura Regarding Co-curricular Activities
Authors: - Dr. Nibas Chandra Sil
Published: August 2023

This study explores the viewpoints of D.EL.ED (Diploma in Elementary Education) trainees enrolled at District Institutes of Education and Training (DIETS) in Tripura, concerning their attitudes towards co-curricular activities. Through a comprehensive investigation, the research aims to gain insights into how these trainees perceive and engage with co-curricular activities within their educational context. By analyzing the perspectives, motivations, and potential benefits or challenges highlighted by the trainees, the study contributes to a deeper understanding of the role and impact of co-curricular activities in the D.EL.ED training program. This research holds relevance for educators, curriculum designers, and policymakers aiming to enhance the holistic learning experience and professional development of future educators.
Exclusionary Religious Discourse and Islamophobia: Impact and Solutions
Authors: - Elhafiz Mohammed Ahmed Elwaly
Published: August 2023

Hate speech cases involving religion are contentious due to community disagreements on balancing restrictions with public freedom, involving complex understandings of religious adherence as a personal and cultural identity. This study aims to promote tolerant religious discourses to lessen hate speech and religious violence by examining the impact of exclusionary religious discourse on Islamophobia. The study revealed that exclusionary religious rhetoric and hate speech are the primary causes of religious intolerance and Islamophobia expansion. To prevent exclusionary religious discourse, people should promote open debate, encourage respectful communication, and establish deterrent laws. Besides, every single member of the society should set a good example by using inclusive language and refraining from harsh language. Moreover, people should recognize common values and principles in all religions to prevent hate speech and protect people's lives from exclusionary religious discourse.
Steroid Hormones Effected in Human Body
Authors: - K.Malleswari , - D.Rama Brahma Reddy , - M.Lakshminarayana , - P.Naga Raju , - P.Vamsi Krishna
Published: August 2023

Disturbances of the steroidogenesis or altered peripheral metabolism of steroids may result in severe clinical manifestations. Therefore, prompt diagnosis and initiation of medical treatment are desirable. The diagnostics of disorders of steroid hormone production, metabolism, and action have been previously based on immunoassay tests. However, in a modern medical laboratory, due to low accuracy of immunoassays, this technique is continuously replaced by chromatographic separation methods coupled to mass spectrometric detection systems. In this review we present current advances in the diagnostics of adrenal gland disorders, focusing on the role of mass spectrometry in prenatal and newborn screening, and in the diagnostics of sexual maturation disorders.
Yeast Fermentation on Agro-industrial Waste for Sustainable Biosynthesis of 2-Phenyl-Ethanol
Authors: - Namrata Patil , - Narendra Kumar , - Rajalaxmi S , - Nargees Kousar
Published: August 2023

The aromatic alcohol 2-phenylethanol (2-PE) has a very high market demand because of its pleasant rosy scent. Consumers and safety regulations tend to favor natural methods of production over synthetic ones for this valuable compound because it is used in food, cosmetics, and pharmaceuticals. Natural 2-PE can be produced either through biotechnological or floral-based methods, such as the extraction of essential oils from roses, hyacinths, and jasmine. The inability to meet the high market demand and the high selling price are actually results of the rarity of natural 2-PE in flowers. Therefore, a biotechnological approach must be developed as a better option to the traditional industrial one that is more effective, affordable, and environmentally friendly. The most promising approach involves microbial fermentation, especially when yeasts are used. Using L-Phe as a precursor, many yeasts can synthesize 2-PE. The distinctive nutritional value of some agro-industrial waste and by-products makes them suitable media for microbial growth, including the production of 2-PE through yeast fermentation. This review provides an overview of the biotechnological production of 2-PE using a variety of yeasts to ferment synthetic media, byproducts, and waste from the agro-industrial sector.
A Review on Drug Design and Development
Authors: - Tanuja Nimbalkar , - Trupti Shelar , - Mohammed Azim Naikwadi
Published: August 2023

A common name for drug design is rational drug design or just rational design. The study of molecule shape is defined as figuring out how molecules adhere to cell receptors or connect to other molecules to trigger a certain reaction .It is supported by Instead of blindly evaluating hundreds of molecules to discover if one or more of them bind cellular or molecular targets, one might use the shape or architecture of the molecules themselves. The drug is an organic substance. When a biomolecule attaches to the target site, it can either inhibit or increase the activity of the biomolecule, producing a therapeutic effect. Development of drug is an very complex process which can take up to around 5-10 years and cost $1.8 billion.
A Cross-sectional Study on Internet Addiction and Social Connectedness among Medical Undergraduate Students at University of Cyberjaya, Malaysia
Authors: - Danesh Pasupati , - Melissa Lee Coe Ann , - Bhavani V. Murugan , - Jaykishen U. Sakathaven , - Myo Wint Zaw
Published: August 2023

In 1995, Dr. Ivan Goldberg proposed the term “internet addiction” and it was defined as pathological compulsive use of internet. Internet addiction affects the quality of relationships in students’ lives. Students tend to lose their interest in socializing and interacting with people when they are addicted to the internet. According to a descriptive study, restriction of the relationship of students with their friends and family members is the main factor of social connectedness weakening. The objective of this study was to determine the association between internet addiction and social connectedness among medical students aged 18 years and above in the University of Cyberjaya (UOC). A cross-sectional online survey was conducted by delivering a google form to medical students at University of Cyberjaya (UOC) through multiple electronic platforms. Most of the respondents (77%) were not internet addicted where most of them were from Year 3 to Year 5 medical students (42.8%). About 68.4% of socially connected respondents were not internet addicted with a significant p value of 0.011 (p<0.05). Furthermore, 45.4% of respondents without social anxiety were not addicted to the internet. Overall, our research shows there is no considerable number of medical undergraduates from the University of Cyberjaya addicted to the internet, and there is no significant impact on social connectedness and social anxiety.
Empowerment and Well-being of Tribal Women in Rural Tripura: A Comprehensive Assessment
Authors: - Dr. Sudhir Chandra Das
Published: August 2023

The aim of this research is to illustrate the prevailing conditions faced by tribal women residing in the rural areas of Tripura. Every individual, irrespective of gender, possesses inherent rights within society. The empowerment of women can be achieved through the avenue of education. India, characterized by its vast expanse and diverse populace, accommodates a multitude of ethnic groups, one among them being the tribal community. A retrospective view of India's recent history unveils the unfortunate disparity that the tribal population has endured within society. Propelling forward as a cohesive society necessitates the imperative task of educating these indigenous communities. The primary objective of this study is to meticulously assess the status of tribal women in the rural environs of Tripura. Furthermore, this paper will delve into an exploration of the living conditions and social standing of tribal women dwelling in the rural landscapes of Tripura.
SEBI: As a Regulator of Capital Market
Authors: - Lakshay Aggarwal , - Ankit Kumar Sharma
Published: August 2023

The Securities and Exchange Board of India (SEBI) stands as a formidable regulator, ensuring transparency, fairness, and investor protection in India's capital markets. Established in 1988, SEBI's multifaceted roles include formulating regulations, promoting investor education, surveilling market activities, and fostering corporate governance. Through its vigilant oversight of market intermediaries and dynamic adaptation to emerging challenges, SEBI has been a cornerstone in shaping a resilient and vibrant financial landscape in India.
Purifying the Narcissist hero; A Feminist study of Kawabata Yasunari’s Snow Country
Authors: - Bandana , - Hemalatha K
Published: August 2023

This study examines the portrayal of women in Yasunari Kawabata's work Snow Country, specifically focusing on their depiction as individuals characterized by vulnerability, subordination, and objectification. Kawabata Yasunari was a renowned Japanese author who was awarded the Nobel Prize in literature for elucidating the Japanese mentality in his writings.In 1938, he released his most celebrated novel, Yukiguni (The Snow Country). Set in a remote hot spring town in the mountainous foothills of northern Japan, Snow Country is a dismal tale of a love affair between a Tokyo socialite and a regional geisha. In the novel, Women are labelled as weaklings. They are the ones who constantly weep and are frequently abandoned, whereas men are the dominant and stronger species. The narrative depicts women solely as sexual objects for males.
प्रेम नारायण 'पंकिल' के काव्य में यथार्थ-वर्णन
Authors: - आमोद प्रकाश चतुर्वेदी , - दिवाकर पाण्डेय
Published: August 2023

कवि प्रेम नारायण 'पंकिल' के काव्य में जीवन के विविध पक्षों का चित्रण मिलता है। मानव के जीवन में उतार-चढ़ाव, प्रेम-प्रतिशोध, घात-प्रतिघात, नियति के थपेड़े, दूसरों के द्वारा किया गये शोषण-उत्पीड़न और उनके विरुद्ध उसका जूझना और अपने संघर्ष के द्वारा परिस्थितियों पर विजय पाना इत्यादि चलते रहते हैं। कभी ये कष्ट प्रकृति प्रदत्त होते हैं तो कभी इनका कारण अपने ही बंधु-बांधव होते हैं। प्रकृति के कोप को तो मनुष्य किसी तरह सह लेता है किंतु अपने समाज में फैली विषमतायें उसे उद्वेलित कर देती हैं। ये विषमतायें कभी आर्थिक होती हैं तो कभी सामाजिक। इनमें पिसना पड़ता है तो मनुष्य को ही। पंकिल जैसे एक सजग कवि की दृष्टि से जीवन का एक भी पक्ष ओझल नहीं हो पाता है। उनके सम्पूर्ण काव्य में मानव जीवन के यथार्थ का चित्रण जहाँ-तहाँ बिखरा पड़ा मिलता है।
Inclusion of Law Ministers in Collegium
Authors: - Eshika Thakur
Published: August 2023

A judge is a lawyer who is a politician who has a friend. Our Supreme Court is also a political court not because judges are politician but because all political disputes are ultimately solved in the court of law. The judiciary should not be solely responsible for the appointment of judges, which is a crucial component of government. The government has made an effort to demonstrate its authority in the process, highlighting the need for a more inclusive framework that includes the executive and legislative branches. To understand the recent debate over our collegium system, it is important to dig deep the constitutionality, history and requirements of the system to be able to answer whether the law minister exclusively be included in the collegium system of India or not. The article aims at elaborating such issues to such context.
Passive Cooling Method Analysis & Optimization of PV Solar Panel Heat Sink
Authors: - Manish Singh , - Kamlesh Kumar Ratre
Published: August 2023

The development of solar photovoltaic (PV) systems in arid climates is hindered primarily by high temperatures, which adversely affect system performance and lifespan. This manuscript presents a comprehensive approach to address this challenge by developing an analytical model for predicting the temperature of PV panels under a passive cooling system specifically designed for arid environments.
The analytical model takes into account the crucial relationship between solar panel temperature and its conversion efficiency. By applying Kirchhoff's and Ohm's laws for a complex circuit, the model accurately calculates the heat flux within the solar panel system, allowing for the determination of temperatures for each layer in the system.
The study deduces closed-form analytical expressions that describe the temperature, output power, and conversion efficiency of the solar panel as functions of various factors, including solar irradiance, ambient temperature, emissivity, wind velocity, tilt angle, and dimensions of fins. These expressions provide valuable insights into the thermal behaviour of the system and enable the evaluation of its performance under different environmental conditions.
Comparative Study of Various Classification and Regression Techniques on Movie Datasets Using R
Authors: - Mareena Fernandes , - Robin Lobo
Published: August 2023

The entertainment industry has been exponentially growing since its inception and is primarily well-received. Creating content, in this case, Movies has been the bread and butter of the industry and has proven extremely lucrative over the years.
In this comparative study, we have picked out various Machine Learning models, viz. Classification Tree, Regression Tree, AdaBoost, SVM (Linear Kernel, Polynomial Kernel, Radial Kernel), XGBoost, Random Forest, Simple Bagging, and Naive Bayes. The Classification models are used to predict the rate of a certain movie winning the Oscar whereas the Regression model implementation estimates the average earning of a film considering the various attributes.