bluuebunny/crossref_metadata_2025 huggingface dataset:
Topoisomerases Modulate the Timing of Meiotic DNA Breakage and Chromosome Morphogenesis inSaccharomyces cerevisiae
Authors: Heldrich Jonna , Sun Xiaoji , Vale-Silva Luis A , Markowitz Tovah E , Hochwagen Andreas
Published: March 2020

Meiotic chromosomes experience substantial strain due to morphological changes and ongoing metabolism of the DNA. Outside of meiosis, topology-modifying enzymes called topoisomerases manage this sort of strain, but their function during meiotic prophase has not been thoroughly explored...

During meiotic prophase, concurrent transcription, recombination, and chromosome synapsis place substantial topological strain on chromosomal DNA, but the role of topoisomerases in this context remains poorly defined. Here, we analyzed the roles of topoisomerases I and II (Top1 and Top2) during meiotic prophase in Saccharomyces cerevisiae. We show that both topoisomerases accumulate primarily in promoter-containing intergenic regions of actively transcribing genes, including many meiotic double-strand break (DSB) hotspots. Despite the comparable binding patterns, top1 and top2 mutations have different effects on meiotic recombination. TOP1 disruption delays DSB induction and shortens the window of DSB accumulation by an unknown mechanism. By contrast, temperature-sensitive top2-1 mutants exhibit a marked delay in meiotic chromosome remodeling and elevated DSB signals on synapsed chromosomes. The problems in chromosome remodeling were linked to altered Top2 binding patterns rather than a loss of Top2 catalytic activity, and stemmed from a defect in recruiting the chromosome remodeler Pch2/TRIP13 to synapsed chromosomes. No chromosomal defects were observed in the absence of TOP1. Our results imply independent roles for Top1 and Top2 in modulating meiotic chromosome structure and recombination.
On the commutativity conditions for rings and $\Gamma$-rings
Authors: KANDAMAR Hatice , ARSLAN Okan
Published: March 2020

Let $R$ be any ring. In this paper we observe the relation between the center of $R$-ring $R$ and the center of usual ring $R$ and then prove if the center of $R$-ring $R$ is nonzero, then $R$ is commutative as a ring. We also show that the common hypothesis\[a\alpha b\beta c=a\beta b\alpha c\: \text{for all}\: a,b,c\in M\:\text{and}\: \alpha,\beta\in\Gamma\]for a weak Nobusawa $\Gamma$-ring $M$ is sufficent for $M$ to be commutative. Also, we investigate some conditions on ideals of $\Gamma$-ring that make $M$ to be commutative.
EMA Recommendation for the Pediatric Indications of Plerixafor (Mozobil) to Enhance Mobilization of Hematopoietic Stem Cells for Collection and Subsequent Autologous Transplantation in Children with Lymphoma or Malignant Solid Tumors
Authors: Karres Dominik , Ali Sahra , van Hennik Paula B. , Straus Sabine , Josephson Filip , Thole Geanne , Glerum Pieter J. , Herberts Carla , Babae Negar , Herold Ralf , Papadouli Irene , Pignatti Francesco
Published: March 2020

On March 28, 2019, the Committee for Medicinal Products for Human Use adopted a positive opinion recommending the marketing authorization for the medicinal product plerixafor. The marketing authorization holder for this medicinal product is Genzyme Europe B.Th. The adoption was for an extension of the existing adult indication in combination with granulocyte colony-stimulating factor (G-CSF) to pediatric patients (aged 1 year to <18 years) to enhance mobilization of hematopoietic stem cells to the peripheral blood for collection and subsequent autologous transplantation in children with lymphoma or solid malignant tumors. This treatment is indicated either preemptively, when circulating stem cell count on the predicted day of collection after adequate mobilization with G-CSF (with or without chemotherapy) is expected to be insufficient with regard to desired hematopoietic stem cells yield, or in children who previously failed to collect sufficient hematopoietic stem cells.

The efficacy and safety of plerixafor were evaluated in an open label, multicenter, phase I/II, dose-ranging, and randomized controlled study (DFI12860) in pediatric patients with solid tumors, including neuroblastoma, sarcoma, Ewing sarcoma, or lymphoma, who were eligible for autologous hematopoietic stem cell transplantation. Forty-five patients (aged 1 year to <18 years) were randomized, 2:1, using 0.24 mg/kg of plerixafor plus standard mobilization (G-CSF with or without chemotherapy) versus control (standard mobilization alone). The primary analysis showed that 80% of patients in the plerixafor arm experienced at least a doubling of the peripheral blood (PB) CD34+ count, observed from the morning of the day preceding the first planned apheresis to the morning prior to apheresis, versus 28.6% of patients in the control arm (p = .0019). The median increase in PB CD34+ cell counts from baseline to the day of apheresis was 3.2-fold in the plerixafor arm versus by 1.4-fold in the control arm.

The observed safety profile in the pediatric population was consistent with that in adults, with adverse events mainly related to injection site reactions, hypokalemia, and increased blood bicarbonate. Importantly, plerixafor exposure did not seem to negatively affect transplant efficiency. This article summarizes the scientific review of the application leading to regulatory approval in the European Union.

Implications for Practice

This review of the marketing authorization of plerixafor will raise awareness of pediatric indication granted for this medicinal product.
Mathematical Model of Fight Against Forest Fires in Terms of Irkutsk Oblast: Computational Experiments in Terms of the Julia Language
Authors: Sukhodolov Alexander , Sorokina Polina , Lebedeva Alina
Published: March 2020

Forest fires extremely undermine the environment, cause serious damage to the forests, wildlife resources and national economy of the country. The issues of fight against forests fires and their prevention are especially important for Eastern Siberia with its huge spaces, low population density and poor development of the road network on the taiga territories. Organizing and delivering largescale fire prevention activities entails enormous financial and material and technical resources Therefore, ecological-mathematical modeling of situations arising from countering forest fires becomes relevant. The purpose of investigations of such models is to develop a fire fighting strategy that would ensure an acceptable environmental level and, at the same time, be economically effective. This article pays attention to solving the problem of optimal control of forest fire fighting, the prototype of which is the well-known model by G.M. Parks. To analyze the model, the modern programming language Julia is used, which is designed to perform mathematical calculations and numerical investigations. It mostly designed for mathematical calculations and numerical analysis of various problems. Irkutsk Oblast has been chosen as a model territory of research.
ÖĞRETMEN VE ÖĞRENCİ GÖZÜNDEN BİR EV ÖDEVİ PORTRESİ
Authors: ALPAYAR Cagla
Published: March 2020

Bu araştırmada,
tipik ev ödevi uygulamalarının yürütüldüğü ilkokul dördüncü sınıftaki ev ödevi
portresinin ortaya konması amaçlanmaktadır. Bu amaca yönelik olarak, öğretmenin
Trafik Güvenliği dersinde verilen üç farklı türdeki ödevden beklentilerinin ne
olduğu ve bu beklentilerin öğrencilerde karşılığını bulup bulmadığı
araştırılmıştır. Bu nedenle de araştırma nitel araştırma deseninde yürütülmüştür.
Katılımcılar, İç Anadolu Bölgesi’nde 2016-2017 eğitim öğretim yılında dördüncü
sınıfta öğrenim gören 25 öğrenci ve bir öğretmendir.  Araştırmanın veri toplama aracı, araştırmacı
tarafından hazırlanan görüşme formlarıdır. Biri öğretmene, diğeri öğrencilere
yönelik olmak üzere iki farklı görüşme formu hazırlanmıştır. Verilerin
analizinde betimsel analiz yönteminden yararlanılmıştır. Buna göre öğretmen
ödevleri eğitsel (derse hazırlık, ders tekrarı, değerlendirme ve genişletme) ve
eğitsel olmayan (sorumluluk bilinci aşılama, araştırma becerisini geliştirme ve
veli ile etkileşimi artırma) amaçlara yönelik olarak vermektedir. Öğrenciler
ise ev ödevlerine yönelik genel olarak olumlu görüşlere sahiptir. Öğretmenin ev
ödevi verirken oluşturduğu beklentilerin de genel anlamda öğrencilerde
karşılığını bulduğu ifade edilebilir.
OKUL MÜDÜRLERİNİN KAYNAŞTIRMA EĞİTİMİNE YÖNELİK YAPILAN YASAL DÜZENLEMELERE İLİŞKİN GÖRÜŞLERİNİN BELİRLENMESİ
Authors: YAZICIOĞLU Tansel
Published: March 2020

Bu araştırmanın amacı, ilkokul ve ortaokullarda görev yapan okul
müdürlerinin, kaynaştırma eğitimi ile ilgili yapılan yasal düzenlemeler
hakkındaki görüşlerini belirlemektir. Araştırma, 2018–2019 eğitim-öğretim
yılında Ankara İli Çankaya İlçesi’nde yürütülmüştür. Araştırmada, okul
müdürlerinin görüşlerini belirlemek amacıyla yarı yapılandırılmış görüşmeler
gerçekleştirilmiştir. Veriler, 2019 yılının Şubat ayında toplanmış ve cep
telefonunun ses kayıt uygulaması kullanılarak kaydedilmiştir. Veriler, nitel
veri analiz tekniklerinden içerik analizi ile analiz edilmiştir. Araştırmada
elde edilen bulgular, kendileriyle görüşme yapılan okul müdürleri ile
gerçekleştirilen görüşmelerden elde edilen verilerin analizi sonucu ortaya
çıkan temalar dikkate alınarak sunulmuştur. 
Araştırmanın sonuçları, ülkemizde kaynaştırma eğitimine ilişkin yapılan
yasal düzenlemelerin yeterli olduğunu, ancak bazı konularda güncel yasal
düzenlemelere gereksinim duyulduğunu, yasal düzenlemelerin uygulanmasında ise
sorunlar yaşandığını ortaya koymuştur. Sonuç olarak ülkemizde özel gereksinimli
öğrencilerin eğitiminde önemli bir eğitim modeli olan kaynaştırma eğitimine
ilişkin yapılan yasal düzenlemelerin gözden geçirilmesi ve uygulamada mevzuata
ilişkin sorunların belirlenmesi gerekmektedir. Uygulayıcıların görüşlerine
dayalı olarak yapılan mevzuat düzenlemesinin uygulamadaki sorunları
azaltabileceği ve birçok yasal boşluğun önüne geçebileceği düşünülmektedir.
ORTAOKUL ÖĞRENCİLERİNİN EV ÖDEVLERİNE İLİŞKİN GÖRÜŞLERİNİN VE EV ÖDEVLERİNİN İNGİLİZCE DERSİ BAŞARISINA ETKİSİNİN BELİRLENMESİ
Authors: KOÇAK Duygu , GÖÇER Özlem
Published: March 2020

Belirli bir program aracılığıyla okulda verilen eğitim ve öğretimin okul saatleri dışında devam etmesini sağlayan tüm ders dışı etkinlikler ödev olarak tanımlanabilir. Bu araştırmada İngilizce dersinde verilen ev ödevlerinin öğrencilerin akademik başarısına etkisini araştırmak ve yarı yapılandırılmış görüşme formu ile öğrencilerin İngilizce dersinde verilen ev ödevleri hakkındaki fikirlerini belirlemek amaçlanmıştır. Bu bağlamda çalışmada hem nicel hem nitel verilerin kullanıldığı karma desen araştırma yöntemi kullanılmıştır. Çalışma 32 6. sınıf öğrencisi ile gerçekleştirilmiştir. Katılımcılar deney ve kontrol grubu olarak iki gruba ayrılmıştır. Deney grubuna ödev verilmiş, kontrol grubuna ödev verilmemiştir. Süreç sonunda uygulanan son test sonuçları, ön test sonuçlarına göre deney grubunun lehine çıkmış ve ev ödevlerinin akademik başarıya olumlu yönde etki ettiği sonucuna ulaşılmıştır. Ayrıca, araştırmaya katılan öğrencilerin çoğunluğu ev ödevlerinin kendileri için yararlı olduğunu belirmiştir. Araştırma sonucunda İngilizce dersi ödevleri yapılırken öğrencilerin karşılaştığı temel sorunların kelimelerin anlamını bilmeme, doğru telaffuz edememe ve doğru yazamama olduğu sonucuna ulaşılmıştır Buna göre, İngilizce dersinde öğrencilere verilen ev ödevleri genellikle okuma ve yazma becerileri ile ilgilidir. Öğrencilere verilen ödevler konuşma ve dinleme becerilerine yönelik olmadığından, bu becerilerde hangi sorunların yaşandığı tespit edilememiştir. Öğrenciler henüz dinleme ve konuşmada yaşadıkları sorunların farkında değillerdir. Bu nedenle dinleme ve konuşma becerilerine yönelik ev ödevlerinin artırılması önerilmektedir.
SINIF ÖĞRETMENİ ADAYLARININ ELEŞTİREL DÜŞÜNME VE YANAL DÜŞÜNME EĞİLİMLERİ ARASINDAKİ İLİŞKİ
Authors: YILDIZ Kaya , YILMAZ Büşra
Published: March 2020

Bu araştırmanın amacı sınıf öğretmeni adaylarının eleştirel düşünme ve yanal düşünme eğilimleri arasındaki ilişkinin belirlenmesidir. Araştırmanın çalışma grubunu 2016-2017 eğitim öğretim yılı bahar döneminde Abant İzzet Baysal Üniversitesi Eğitim Fakültesi Sınıf Öğretmenliği Anabilim dalında öğrenim görmekte olan toplam 327 öğretmen adayı oluşturmaktadır. Bu araştırmada ilişkisel tarama modeli kullanılmıştır. Araştırmada veri toplama aracı olarak “Eleştirel Düşünme Eğilimi Ölçeği” ve “Yanal Düşünme Eğilimi Ölçeği” kullanılmıştır. Öğretmen adaylarının, eleştirel düşünme eğilimlerinin ve yanal düşünme eğilimlerinin cinsiyet değişkenine göre değişimini belirlemek amacıyla bağımsız örneklem t testi, sınıf düzeyi değişkenine göre değişimlerini belirlemek amacıyla ilişkisiz örneklemler için tek faktörlü varyans analizi kullanılmıştır. Öğretmen adaylarının eleştirel düşünme eğilimi puanları ve yanal düşünme eğilimi puanları arasındaki ilişkinin belirlenmesi amacıyla Pearson Momentler Çarpımı Korelasyon Katsayısı kullanılmıştır. Yapılan analizler sonucunda elde edilen bulgular doğrultusunda sınıf öğretmeni adaylarının yanal düşünme eğilimi ve eleştirel düşünme eğilimlerinin yüksek düzeyde olduğu, eleştirel düşünme eğilimi puanlarının cinsiyet ve sınıf düzeyine göre anlamlı farklılık gösterdiği sonucuna ulaşılmıştır. Sınıf öğretmeni adaylarının yanal düşünme eğilimi puanları sınıf düzeyine göre anlamlı farklılık göstermesine karşın cinsiyet değişkenine göre anlamlı farklılık göstermemektedir. Ayrıca sınıf öğretmeni adaylarının yanal düşünme eğilimi ölçeği puanları ile eleştirel düşünme eğilimi ölçeği puanları arasında orta düzeyde pozitif yönde ve anlamlı bir ilişki olduğu sonucuna ulaşılmıştır.
EĞİTİM FAKÜLTESİ ÖĞRENCİLERİNİN ÖZ DÜZENLEME ÖĞRENME STRATEJİLERİNİN VE AKADEMİK BAŞARILARININ ÖZ YETERLİK İNANÇLARINI YORDAMA GÜCÜ
Authors: DAĞYAR Miray , Şahin Harun
Published: March 2020

Çalışmanın amacı, Eğitim Fakültesi öğrencilerinin kendi öğrenme süreçlerinde kullandıkları bilişsel (yineleme, açımlama, düzenleme, eleştirel düşünme), metabilişsel ve zaman/çevre yönetimi öz düzenleyici öğrenme stratejilerinin ve akademik başarılarının, öğrencilerin öz yeterlik inançları üzerindeki ortak etkisini belirlemektir. Çalışmanın örneklemine, Akdeniz Üniversitesi Eğitim Fakültesi’nde öğrenim gören 211, 3. sınıf lisans öğrencisi dâhil edilmiştir. Öğrencilerin öz düzenleyici öğrenme stratejilerini ve öz yeterlik inançlarını belirleyebilmek için “Güdülenme Ölçeği ve ve Bilişsel, Metabilişsel ve Zaman/Çevre Yönetimi Ölçeği’nden” yararlanılmıştır. Çalışmada, değişkenler arasındaki ilişkiler, çoklu doğrusal regresyon analizi ile belirlenmiştir. Çoklu regresyon analizi sonucuna göre; bilişsel, metabilişsel, zaman/çevre yönetimi öz düzenleyici öğrenme stratejileri ve akademik başarı yordayıcı değişkenleri birlikte, öğrencilerin öğrenmeye yönelik öz yeterlik inançları ile orta düzeyde ve anlamlı bir ilişki göstermektedir. Elde edilen bulguya göre, belirtilen yordayıcı değişkenlerin birlikte, öğrenci öz yeterlik inancının yaklaşık %32’sini açıkladığı söylenebilir. Çalışmadan elde edilen standardize edilmiş regresyon katsayılarına göre, yordayıcı değişkenlerin, öğrencilerin öz yeterliği üzerindeki önem sırası; açımlama, eleştirel düşünme, akademik başarı, düzenleme, metabilişsel, zaman/çevre yönetimi, yineleme stratejileridir.
SIRALI LOJİSTİK REGRESYON VE POLY-SIBTEST YÖNTEMLERİ İLE DEĞİŞEN MADDE FONKSİYONUNUN BELİRLENMESİ
Authors: SIRGANCI Gözde , ÇAKAN Mehtap
Published: March 2020

Bu çalışmanın amacı psikometride önemli bir geçerlik sorunu teşkil eden madde yanlılığının belirlenmesinde kullanılan farklı değişen madde fonksiyonu yöntemlerini kullanarak yöntemlerin uygulamadaki benzerlik ve farklılıklarının ortaya konmasıdır. Bu amaçla alanyazında kullanılan iki yöntem olan sıralı lojistik regresyon ve poly-SIBTEST yöntemleri ile değişen madde fonksiyonu analizleri yapılmıştır. Yöntemlere ilişkin değişen madde fonksiyonu analizleri, PISA 2006’da uygulanan bir öğrenci anketi maddelerine uygulanmıştır. Çalışma grubu ise kültürel ve dilsel farklılıkları yansıtan Avustralya, Yeni Zelanda, Amerika Birleşik Devletleri ve Türkiye olmak üzere dört ülke verisinden oluşmaktadır. Verilerin analizi aşamasında öncelikle öğrenci anketinin her bir ülkedeki faktör yapısı doğrulayıcı faktör analizi ile incelenmiştir. Devamında, sıralı lojistik regresyon ve poly-SIBTEST yöntemleri ile ölçme aracının benzer-farklı kültür ve dillerde değişen madde fonksiyonu analizi yapılmış olup yöntemlerin değişen madde fonksiyonunu belirleme benzerlikleri incelenmiştir. Doğrulayıcı Faktör Analizi bulguları ölçme aracının her bir ülkede aynı faktör yapısına sahip olduğunu göstermiştir. Sıralı lojistik regresyon ve poly-SIBTEST yöntemleri ile yapılan değişen madde fonksiyonu analiz bulguları ise ülkeler arasında kültürden ve dilden kaynaklı farklılıklar arttıkça değişen madde fonksiyonlu madde sayısında artış olduğunu göstermiştir. Yöntemlerin uyumları incelendiğinde ise her iki yöntemin değişen madde fonksiyonu belirlemede uyumlu olduğu; ancak poly-SIBTEST yöntemi ile daha hassas DMF analizinin yapıldığı belirlenmiştir.
Can telomere length predict bone health? A review of current evidence
Authors: Wong Sok Kuan , Ima-Nirwana Soelaiman , Chin Kok-Yong
Published: March 2020

Telomeres are repetitive DNA sequences located at the end of chromosomes, which serve as a protective barrier against chromosomal deterioration during cell division. Approximately 50–200 base pairs of nucleotides are lost per cell division and new repetitive nucleotides are added by the enzyme telomerase allowing telomere maintenance. Telomere shortening has been proposed as an indicator for biological ageing, but its relationship with age-related osteoporosis is ambiguous. We summarize the current evidence on the relationship between telomere length and bone health in experimental and epidemiological studies, which may serve as a scientific reference for the development of novel diagnostic markers of osteoporosis or novel therapeutics targeting telomere and telomerase in bone cells to treat osteoporosis.
Syntaxic tools for creating the image of Ukraine in media space
Authors: Pliasun Olga
Published: March 2020

The article analyzes syntactic potential of constructing the image of Ukraine in modern mass media. The author argues for the need to apply a comprehensive approach to the analysis of language tools of image construction. In particular, the scholar emphasizes the importance of exploring different types of image media texts that are the main carriers of image information about the country. The scientist’s attention is focused on the ambivalence of most image texts, which, depending on the author's intention, subjective interpretation of the information covered can have both a positive and a negative impact on the state image. The paper consistently proves that the features of constructing the image of Ukraine are most clearly revealed at the syntactic level, which is explained by the specific intonation of the phrase, the emotional-evaluative nature of the presentation of the material, etc. The image potential of different types of oppositions, where the first component forms a positive state image and the second component contributes to the formation of a negative image of Ukraine, is analyzed. Moreover, a highly productive syntactic tool for shaping the image of the country is syncrisis based on contextual opposition. Equally effective in the process of constructing the state image is the use of expressive syntax. Thus, in particular, the use of rhetorical exclamations in image media publications with meliorative meaning contributes to the construction of a positive state image. At the same time, rhetorical questions introduced into the image text often have pejorative semantics and thus form a negative image of Ukraine. In addition, effective syntactic means of creating state image in media are anepiphor, parceling and antiphrase statements that emphasize the author's attitude to the events described. The conducted research convinces that the syntactic system of language represents a wide palette of expression of author’s modality, subjective-evaluative interpretation of information and, as a result, the image of the state that is formed in the mass consciousness.
Strategic narratives in the system of mechanisms for countering informational influence
Authors: Snytko Olena
Published: March 2020

The study addresses the issue of strategic communications in Ukraine’s information space. It defines strategic communications as a system of informational multi-dimensional interaction with the public on socially relevant topics through diverse mass media outlets directed at promoting national goals. Strategic communications aim at exerting influence on the individual by appealing to the freedom of speech principle and providing strong encouragement towards independent decision-making, as well as by drawing the public’s attention to socially relevant issues and the ways to approach them. Strategic communications entail the emergence of distinct strategic narratives. Therefore, gaining a better insight into strategic narratives allows determining the causes of the socially significant situation and the prospects for its resolution. The paper explores the narrative about the origin of the Ukrainians, which is steadily unfolding in the information space. This narrative represents a distinct multimodal semantic plural aimed at promoting the idea of national identity and statehood. The study has found that different versions of the strategic narrative about the origin of the Ukrainians in the Internet space have similar semantic and conceptual patterns and involve multiple narrators. At the same time, they provide varying amounts of information and commenting features, target different audiences, and, for this reason, require relevant tools of influence, namely argumentation and suggestion. Тhe methods of randomizing ideas, breaking patterns, and creating cognitive dissonance are widely used in the creolized political texts. In the context of information warfare, a powerful strategic narrative, as a rule, instigates the emergence of a counter-narrative, which has an asymmetrical structure. The struggle of narratives has become the dominant feature of modern media space.
Seismicity of the Erguna Region (Northeastern China): Evidence for Local Stress Redistribution
Authors: Seredkina Alena I. , Melnikova Valentina I. , Radziminovich Yan B. , Gileva Nadezhda A.
Published: March 2020

We consider the seismicity of the Erguna region in northeast China (48°–51° N, 117°–123° E) which is poorly studied from seismological point of view as it is characterized by a low level of seismic activity. We calculate focal parameters (focal mechanisms, scalar seismic moments, moment magnitudes, and hypocentral depths) for seven regional earthquakes with Mw 4.2–4.6 that occurred in 2000–2017 using global seismic data of Rayleigh- and Love-wave amplitude spectra and P-wave first-motion polarities recorded at regional stations. It has been shown that the study earthquakes are of small magnitudes (Mw 4.2–4.6), of various hypocentral depths (3–37 km), and are characterized by different kinematics in their sources (normal and thrust faults, strike slips). The different faulting mechanisms could reflect local stress redistribution in small-scale crustal blocks bordered by local short-length nonconnecting faults. The available geophysical and geological data evidence that the observed features of the seismic process in the Erguna region—low-seismic activity and inhomogeneity of the stress-strain field—are likely to be controlled by the structure of the crust and the upper mantle.
Uczeń zdolny w rzeczywistości polskiej szkoły
Authors: Bochniarz Agnieszka , Grabowiec Anna
Published: March 2020

Potencjał osób zdolnych stanowi niezwykle ważny zasób każdej społeczności. Istotne jest więc, aby w świadomości wszystkich uczestników procesów edukacyjnych pojawiła się na stałe kategoria „zdolności” i „ucznia zdolnego” jako wartości. W artykule przedstawiono problematykę dotyczącą pracy z uczniem zdolnym. W części wstępnej przybliżono pojęcie i charakterystykę uczniów zdolnych, ze zwróceniem uwagi na syndrom nieadekwatnych osiągnięć oraz zaburzenia rozwojowe, takie jak asynchronia rozwojowa. Wskazano na rolę i zadania szkoły w kontekście szczególnego wsparcia, jakie instytucja ta powinna zapewnić uzdolnionym uczniom. W artykule zaprezentowano ponadto wyniki badań dotyczących opieki nad uczniami zdolnymi w polskich szkołach. Na koniec przedstawiono przykłady „dobrych praktyk” wspomagających działania szkoły w projektowaniu edukacji uczniów zdolnych.
Van İlinin Çaldıran İlçesinde Yetişen Bazı Tıbbi Bitkilerin Toplam Fenolik ve Flavonoid Madde Miktarlarının Belirlenmesi
Authors: İRTEM KARTAL Deniz , ERAY Neşe , ÖZTÜRK Fazlı
Published: March 2020

Çalışmanın amacı, Çaldıran/Van’da yetişen ve halk arasında sıkça tüketilen bazı tıbbi bitkilerin, toplam fenolik (TFM) ve flavonoid (TF) miktarlarının belirlenmesi ve farklı organlardan elde edilen su ekstrelerindeki olası farkların ortaya konmasıdır. Alcea pallida (Hiro) (Willd.) Waldst. &. Kit., Rumex scutatus L. (Evelik), Mentha longifolia (L.) L. (Dağ Reyhanı), Erigeron acris L., Achillea vermicularis Trin. (Civan Perçemi) bitkileri Van/Çaldıran'dan toplanmıştır. Ekstrelerin TFM ve TF içerikleri spektrofotometrik olarak ölçülmüştür. En yüksek TFM ve TF madde E. acris bitkisinin tohum ekstresinden elde edilmiştir. Aynı bitkinin gövde ekstresi ve M. longifolia tohum ve gövde ekstreleri de yüksek fenolik ve flavonoid madde taşıyan bitki kısımları olmuştur. Sonuçta, kullanılan beş farklı bitkiden alınan çiçek, gövde ve tohum ekstrelerinin hepsinde çiçek ve/veya tohum ekstrelerinin gövde ekstrelerine göre daha verimli olduğu ortaya konmuştur. E. acris ve M. longifolia bitkilerinden elde edilen sonuçlar, bu bitkilerin tıbbi amaçlara uygun olarak kullanılabileceğini, hem tohum hem gövde kısımlarının yoğun fenolik ve flavonoid içerdiğini göstermiştir.
Diyarbakır İlinde Yetişen Badem Ağaçlarından Endofit ve Epifit Bakteri Türlerinin İzolasyonu ve Bitki Gelişimini Teşvik Eden Mekanizmalarının Karakterizasyonu
Authors: AKTAN Zekiye Ceren , SOYLU Soner
Published: March 2020

Bu çalışmanın amacı, sağlıklı badem ağaçlarından izole edilen bitki gelişimini teşvik eden endofit ve epifit bakteri (PGPB) türlerin tanılanması ve bitki gelişimini teşvik eden mekanizmalarının belirlemektir. MALDI-TOF tanılama analizleri sonucu, 19 izolat Gram-negatif Serratia, Pseudomonas, Ochrobactrum ve Enterobacter, 26 izolat ise Gram-pozitif Bacillus ve Arthrobacter cinsine dahil türler olarak teşhis edilmiştir. Test edilen izolatlardan, 46 izolat siderofor, 45 izolat amonyak üretiminde pozitif, 35 izolat ise fosforu değişen oranlarda çözebilme yeteneğinde olurken, bakterilerin tamamı 5.48-127.81 µg/ml konsantrasyon aralığında IAA üretmişlerdir. Pseudomonas spp and Enterobacter cloacae izolatları siderofor, Serratia marcescens izolatları fosforu çözme, Enterobacter cloacae izolatları IAA üretme, Bacillus spp ise amonyak üretme etkinliğinin yüksek düzeylerde olduğu görülmüştür. Aynı türe bağlı endofit bakteri izolatları epifit bakteri izolatlarına kıyasla bu mekanizmaları daha düşük düzeyde teşvik ettiği belirlenmiştir. Elde edilen sonuçlar yüksek düzeyde siderofor, amonyak, IAA üretimi ile fosfor çözme gibi bitki gelişimini teşvik edici özellikleri sahip PGPB izolatlarının ekonomik öneme sahip kültür bitkilerin yetiştiriciliğinde biyolojik gübre olarak kullanılmada potansiyeline sahip olduğunu göstermiştir.
Fortalecimiento de la calidad educativa a partir de los convenios de cooperación interinstitucional: un caso desde la educación artística
Authors: Barragán Parra Leidy Johanna , Camargo Lombana Carolina
Published: March 2020

This research study focused on the contributions (formulation, implementation, evaluation and feedback) of an inter-institutional academic cooperation agreement, in which strategies were co-constructed, theories were privileged and practices were rethought, aiming at institutional improvement and the qualification of teachers and teachers in training. In the diagnosis, a set of needs were identified in the area of Artistic Education, in terms of knowledge construction, teachers’ role and disciplinary training. As an opportunity for improvement, actions aimed at educational quality were formulated, emphasizing criteria such as pedagogical innovation. Therefore, once this agreement was implemented, the pedagogical incidence in the related institutions was studied, and the findings were evidenced, mainly in the transformation of the pedagogical practices of active teachers and teachers in training, and, therefore, in the improvement of educational quality.
Device associated infections among neonates in neonatal intensive care units: a single unit survey study in Cairo, Egypt
Authors: Ibrahim Mohamed Farouk M. , Mohamed Hanem Abdullah , Abdelfattah May , ElTatawy Sara S.
Published: March 2020

Background: Device Associated Infection (DAI) namely Ventilator Associated Pneumonia (VAP) and Central Line Associated Blood Stream Infection (CLABSI) is one of the challenges for both neonatal nurses and doctors. Aims of the study were 1) Assess the rate of DAI occurrence among neonates, 2) explore the relationship between DAI rates and certain risk factors such as nurse patient ratio, hand hygiene practice, gestational age (GA), weight, and length of hospital stay among neonates.Methods: Descriptive correlational survey research design. Sample: All neonates admitted in twelve months-duration were included (total number 1090 neonates). Nurses and doctors were observed for compliance to adequate hand hygiene technique. Tools: 1) Center for Disease Control (CDC) criteria to calculate DAI rates, 2) Hand hygiene five points checklist 3) Review of neonates charts to collect data as weight, GA 4) Ballard score and 5) nurse/patient ratio.Results: 24 neonates developed DAI, high significant negative correlations between DAI and infants’ weight, GA, nurse/patient ratio and overall compliance to hand hygiene techniques were reported (p-value ≤0.05). Length of hospital stay, inadequate hand hygiene technique had strong positive correlations with DAI rate (p-value ≤0.05).Conclusions: Factors that could affect DAI were infant’s weight, GA, length of hospital stay, inadequate hand hygiene technique and nurse/patient ratio. Recommendations: implementation of infection control programs to raise nurses as well as physicians’ compliance to adequate hand hygiene technique and increase number of nurses in the Neonatal Intensive Care Unit (NICU) per shift.
TEGDroid: Test Case Generation Approach for Android Apps Considering Context and GUI Events
Authors: Usman Asmau , Ibrahim Noraini , Salihu Ibrahim A
Published: March 2020

The advancement in mobile technologies has led to the production of mobile devices (e.g. smartphone) with rich innovative features. This has enabled the development of mobile applications that offer users an advanced and extremely localized context-aware content. The recent dependence of people on mobile applications for various computational needs poses a significant concern on the quality of mobile applications. In order to build a high quality and more reliable applications, there is a need for effective testing techniques to test the applications. Most existing testing technique focuses on GUI events only without sufficient support for context events. This makes it difficult to identify other defects in the changes that can be inclined by context in which an application runs. This paper presents an approach named TEGDroid for generating test case for Android Apps considering both context and GUI Events. The GUI and context events are identified through the static analysis of bytecode, and the analysis of app’s permission from the XML file. An experiment was performed on real world mobile apps to evaluate TEGDroid. Our experimental results show that TEGDroid is effective in identifying context events and had 65%-91% coverage across the eight selected applications. To evaluate the fault detection capability of this approach, mutation testing was performed by introducing mutants to the applications. Results from the mutation analysis shows that 100% of the mutants were killed. This indicates that TEGDroid have the capability to detect faults in mobile apps.
Technology Integration to Promote Desire to Learn Programming in Higher Education
Authors: Husin Nurul Faeizah , Mohamad Judi Hairulliza , Hanawi Siti Aishah , Mohd Amin Hazilah
Published: March 2020

The use of technology integration is the way of innovation in today’s world-class learning. Technology integration is a combination of technologies such as computers, mobile devices like smartphones and tablets, digital cameras, the internet, and more in the practice of daily lecture sessions. Technology integration could help the process of learning especially for courses that considered as tough by the students. Therefore, educators need to be aware of the choice of methods or approaches so that teaching and learning are conducted in meaningful ways. Programming courses are compulsory for students in Faculty of Information Sciences and Technology, National University of Malaysia. However, some students find it difficult to excel in programming courses. In this study, technology integration in learning programming courses challenges the limitations of student opportunities in solving real problems lead to inconsistently use of the expertise and skills. In addition, the challenge of learning programming leads students to generate rote learning. Hence, technology integration in learning programming should be appropriate with the application of technology and applying meaningful learning so that the technology integration will be effective and meaningful. This study is conducted to propose and verify a technology integration framework for learning programming courses. Stratified Random Sampling through quantitative study method is used which involving 109 respondents. Quantitative data are analyzed using multiple linear regression method. Based on previous studies, five factors have been identified namely learning technology, learning competence, technology implementation, meaningful learning and contextual learning that would affect students’ desire to learn programming courses. The results discover that all the factors have significant relationships in influencing the desire to learn programming courses among undergraduate students for the faculty. This study is expected to assist educators and administrators to apply and improve the use of technology integration in meaningful learning for programming courses.
Seismic Vulnerability Mapping to Support Spatial Plans in Lhokseumawe City Area
Authors: Siska Deassy , Fithra Herman , Lisa Nova Purnama , Haerudin Nandi , Farid Muhammad
Published: March 2020

Earthquake loads that work on building structures can be determined by doing calculations ground motion on the surface. The amplitude from ground vibration is correlated with earthquake energy and ground solidity (compaction). The ductile ground will amplify the earthquake energy so that it produces strong vibration to the ground and building on the surface. This study will provide a mapping of areas susceptible to seismic vibrations to produce sustainable Lhokseumawe City spatial management plan policies as supporting literature in City development planning. The results of the study are expected to be disseminated to the community and as input for the Regional Government in planning the development of the city of Lhokseumawe. This research contributed to the development of cross-sectoral science in the assessment of the danger of micro seismic earthquakes. The results of the study were mapping areas that were susceptible to seismic vibration as a basis for spatial planning for the city of Lhokseumawe. The essential linkages in the field of science are on geophysics and architecture. The needs of the study carried out micro seismic data collection in the Lhokseumawe area using micro seismic equipment. The results of this study are the existence of areas that are very susceptible to seismic, namely Ujong Blang and Banda Sakti villages with seismic vulnerability index values (Kg) ranging from 0 cm / s2 - 30542.32 cm / s2. The highest value is located at Ujong Blang Village start from point A10, which is 10397.1 cm / s2. This is finally related to the full damage to buildings in Lhokseumawe City during the 2004 earthquake.
Urgent Measure of Geospatial Parameters for Flood Modeling in Indonesia
Authors: Andreas Heri , Sarsito Dina A , Yuherdha Angga Trysa , Pradipta Dhota
Published: March 2020

Indonesia is prone to flood. Many areas including cities have a suffering flood in history until these recent days.  Jakarta city, for example, had suffering flood since Dutch colonial time a few hundred years ago and even earlier until this recent year 2018. Besides Jakarta, Indonesia has other big cities like Bandung, Semarang, Surabaya and Medan which frequently suffered from the flood. Growing cities like Langsa, Pekanbaru, Palembang, Pamanukan, Garut, Cirebon, Pekalongan, Demak, Bojonegoro, Banjarmasin, Gorontalo, Bima are also suffering flood in almost regularly. The flood condition is different from time to time due to rain intensity and rivers capacity are leading to disaster.  Low land areas such as coastal areas and peatland areas in many regions of Indonesia are experiencing the same disaster. Adaptation and mitigation should be taken against this flood disaster. In order to find the best adaptation and mitigation, first, we must understand the characteristic of the flood by creating flood models. Essential parameters of flood modeling would include geospatial parameters (e.g., Digital Elevation Model, Land use, and rivers geometry).  Unfortunately for Indonesia's case, these geospatial parameters of the flood are still relatively weak.  We can see that several flood models of Indonesia are in low accuracy spatially and temporarily. So, the measure of geospatial parameters is urgent. This paper will highlight this urgency.
Multiple Sensor on Clustering Wireless Sensor Network to Tackle Illegal Cutting
Authors: Mutiara Giva Andriana , Suryana Nanna , Mohd Othman
Published: March 2020

This paper is intended to purpose a designed system using Wireless Sensor Network application. It is multiple sensors to tackle illegal cutting in the stage of a timber harvesting. This paper also discusses network performance and the costs of the purposed system. In every node in the networks, the system was built using a combined sound sensor and vibration sensor in which incorporated using Xbee Pro S2C. It is considered as a communication module at each sensor node and Arduino Nano to process the data.  The Wireless Sensor Network has been designed in three networks with the configuration of master and slave nodes in each network. This system was testing using several scenarios to have the data performance of the networks and the performance of the proposed system in the small forest and the opened area. The costs of the purposed system also compared related to the previous system. The result showed the optimum distance that can be applied in the WSN network as a real-time application using Xbee Pro S2C is less than 30 meters; meanwhile the time consumed to communicate between nodes is below 5 s. Therefore, the more slaves in the subnetwork will affect the performance of the system. The proposed system runs smoothly as predicted in the purposed system. All the testing is 100% completed and can be handled by the proposed system.
Identificación y valoración neuropsicológica del riesgo perinatal: instrumentos
Authors: López-Gómez Santiago , Cajal-Cernuda Carlos José , Ordóñez-Blanco Sonia Mª , Uribe-Rodríguez Ana Fernanda
Published: March 2020

Algunas complicaciones maternas perinatales específicas pueden ser determinantes en el desarrollo infantil. Se constata que muchos niños con una amplia variedad de alteraciones han sufrido diversas complicaciones durante su desarrollo gestacional. Por lo tanto, los riesgos maternos ocurridos a lo largo del período pre-perinatal llevan asociados, en ocasiones, diferentes daños, sean neuropsicológicos, físicos y/o psicosociales. En el presente artículo se identifican los principales factores asociados al riesgo perinatal y sus implicaciones, haciendo un recorrido por los procedimientos estandarizados de evaluación del riesgo, desde la perspectiva médico neuropsicológica y psicosocial del neonato.
Displasia tanatofórica. Reporte de un caso y revisión
Authors: Giraldo-Cuartas Alejandro
Published: March 2020

Objetivo: presentar los hallazgos ecográficos de la displasia tanatofórica (DT) y su diagnóstico diferencial, desde el punto de vista del ultrasonido con la acondroplasia. Se presenta un caso clínico de una paciente gestante a quien se remitió con diagnóstico de feto con acondroplasia, y posterior a una ecografía de detalle fetal 2D-3D, se hizo el diagnóstico antenatal de displasia tanatofórica (DT), el cual se confirmó postmortem.Conclusión: se resalta la necesidad de afinar los criterios diagnósticos de la restricción del crecimiento, partiendo de reportar los hallazgos ecográficos en función del percentil de crecimiento fetal y no de la reasignación de una nueva edad gestacional con cada nueva ecografía, además se hacen algunas recomendaciones respecto al informe ecográfico.
Parsonage-Turner syndrome presenting with left shoulder pain and weakness: a case report
Authors: KULAKLI Fazıl , DUMAN Sencer
Published: March 2020

Parsonage-Turner syndrome is a clinical syndrome that begins with a sudden, neuropathic pain on the shoulder girdle, followed by pain loss over time. It is a rare syndrome that can be overlooked during differential diagnosis of shoulder pain and weakness. In this paper, we aimed to present a 39-year-old male patient with sudden onset left shoulder pain and weakness who were diagnosed with Parsonage-Turner syndrome.
Análisis de la producción narrativa en niños desde las propuestas de Karmiloff, Karmiloff y Owens
Authors: Gutiérrez Angie Tatiana , Fernández María Fernanda
Published: March 2020

El presente artículo tiene como propósito evidenciar el proceso narrativo oral de los niños. El análisis de las narraciones se hizo desde las teorías de Kira Karmiloff y Annette Karmiloff y de Robert Owens. Se encontraron producciones orales con frases cortas y uso restringido de los conectores textuales. Se concluye que la narración oral de los niños presenta dificultades en la construcción de sus relatos, con respecto a la cohesión, además, algunas producciones no cuentan con la estructura espacio temporal, la descripción de los personajes es corta, por tales razones, cabe señalar que la enseñanza del Español es pertinente para mejorar las producciones narrativas al hacer énfasis en los aspectos gramaticales y sintácticos, para que las narraciones sean más coherentes y cohesionadas.
Procesos de visualización en la resolución de problemas de matemáticas en el nivel de básica primaria apoyados en ambientes de aprendizaje mediados por TIC.
Authors: Gutiérrez Zuluaga Heiller , Aristizabal Zapata Jorge Hernán , Rincón Penagos Julián Andrés
Published: March 2020

Las matemáticas contribuyen al desarrollo integral de los estudiantes para su integración a la sociedad; en el departamento del Quindío en los últimos años, se evidencia en los resultados de las Pruebas Saber de grado 3° y 5° que los estudiantes presentan diversas dificultades en matemáticas, una de las causas es la dificultad que les genera enfrentarse a la resolución de problemas. Esto se debe a que muchos docentes en ocasiones dan poca trascendencia a ciertos procesos como sucede con  los procesos de visualización, como lo señala Zimmermann y Cunningham (2013, citado por Martinovic, Freiman y Karadag p. 213) la visualización en los procesos de aprendizaje de la matemática contribuye al desarrollo de una comprensión más profunda y significativa tanto de las ideas matemáticas y las relaciones entre los conceptos matemáticos, o desconocen el potencial que poseen los ambientes de aprendizaje y la integración de las TIC, que hacen trascender el aula física, enriqueciéndola con nuevas alternativas pedagógicas y dando a los estudiantes experiencias significativas y mejores oportunidades de aprendizaje. Por lo anterior se desarrolló la investigación bajo una metodología cualitativa de tipo interpretativa (Sampiere, Fernandez y Batista 2010), cuyo objetivo fue analizar incidencias de los procesos de visualización apoyados con ambientes TIC, en la resolución de problemas de matemáticas, por estudiantes de la educación básica primaria, encontrándose mediante la implementación de los software educativos que la visualización juega un papel muy importante en cuanto a los estilos de resolución de problemas de los estudiantes, de acuerdo a la categorización de las tareas propuestas.
Method for Estimating the Efficiency of Small Orbital Spacecraft Systems for Optoelectronic Surveillance
Authors: Protsenko P.A. , Khubbiev R.V.
Published: March 2020

The paper presents the results of analysing existing approaches to estimating how efficient small orbital spacecraft systems are for the purpose of optoelectronic surveillance, including determining their shortcomings. We simulated employing an orbital system required to ensure surveying the earth surface at various latitudes, accounting for sunrise and sunset time on the winter and summer solstice days, and discovered that the following parameters show low sensitivity: average daily object sighting number at a preset latitude and maximum time delay between object sightings at a preset latitude. We propose a new efficiency factor reflecting a confidence interval regarding the object sighting time delay. We developed a procedure utilising the factor proposed, expanding the scientific methodology in terms of estimating how efficient small orbital spacecraft systems are for optoelectronic surveillance. We obtained object sighting time delays at a preset latitude as functions of the probability of these delays occurring. We recommend using this procedure to estimate the efficiency of jointly employing several small orbital spacecraft systems and incomplete composition systems, as well as to state and solve the problem of synthesising the ballistic structure of an orbital system intended to improve the efficiency of earth surveillance.
Wpływ programu 500 plus na ewolucję demograficzną polskiego społeczeństwa
Authors: Błaszczyk Alina , Sawicka Justyna
Published: March 2020

W artykule obserwacji i ocenie poddany został program 500 plus jako jeden z kluczowych determinantów obecnej sytuacji ekonomicznej polskiego społeczeństwa. Rozpatrywano znaczenie programu 500 plus, w szczególności biorąc pod uwagę jego wpływ na rozkład wydatków (przy rozróżnieniu wielkości dochodów rodzin), poziom dzietności czy stopę bezrobocia. Celem artykułu jest wskazanie korelacji pomiędzy wprowadzonym świadczeniem finansowym a takimi wskaźnikami ekonomicznymi, jak uzyskiwany poziom dochodów, wskaźnik urodzeń czy poziom zamożności. Do przeprowadzenia wnioskowania posłużyły badania wtórne z wykorzystaniem literatury przedmiotu, a także dostępnych ustaw i ich nowelizacji od 2016 roku.
Niespójność systemu emerytalnego i systemu rentowego w Polsce
Authors: Błoch Wiktor
Published: March 2020

Celem artykułu jest przeanalizowanie problemu niespójności systemu rentowego i emerytalnego w Polsce pod względem wysokości otrzymywanych świadczeń. Artykuł składa się z czterech części. W pierwszej scharakteryzowano system rentowy, koncentrując się na sposobie ustalania wysokości świadczeń. Następnie przedstawiono ewolucję systemu emerytalnego, zwracając uwagę na zmiany wynikające z reformy wprowadzonej w 1999 roku. W trzeciej części przeprowadzono dwie symulacje kształtowania się relacji świadczenia rentowego do wynagrodzenia, uwzględniając zarobki oraz staż pracy ubezpieczonego. Otrzymane wyniki porównano ze stopami zastąpienia osiąganymi w systemie emerytalnym. Podkreślono fakt, że zasady ustalania wysokości świadczeń w systemie rentowym są znacznie korzystniejsze. W ostatniej części przedstawiono propozycje zmian systemowych prowadzące do zwiększenia spójności obu systemów i zredukowania relatywnych różnic w wysokości otrzymywanych świadczeń.