bluuebunny/crossref_metadata_2025 huggingface dataset:
3D-TSE Dixon sequence with preserved short echo spacing for second and subsequent echoes
Authors: Stemmer Alto , Nickel Dominik , Schäfer Andreas
Published: November 2024

Motivation: Common to existing TSE Dixon sequences is that the chemical shift between water and fat is encoded by shifting the readout window away from the spin-echo time point. The shifting prolongs the echo spacing by twice the shift. A short echo spacing is an important component of modern 3D-TSE sequences to enable high resolution 3D imaging in clinically acceptable times. Goal(s): Develop a 3D-TSE Dixon sequence with unchanged echo spacing. Approach: Encode the chemical shift via the excitation. Acquire in-phase and opposed-phase data for 2pt-Dixon symmetric around the spin-echo time point. Results: Homogeneous fat-water separation in knee, hand and ankle. Impact: 3D-TSE 2pt-Dixon sequence with unchanged echo spacing between second and subsequent echoes compared to a conventional 3D-TSE sequence with same acquisition parameters.
Investigating Data Acquisition Strategies for High Efficiency Clinical MRI and a More Sustainable Future in Radiology
Authors: Becker Amy , Martin Alastair , Deshpande Vibhas , Su Pan , Itriago Pedro , Lam Vincent , Hess Christopher , Woolen Sean
Published: November 2024

Motivation: Recognizing Radiology’s role in the medical healthcare environmental impact, we investigate strategies to reduce MRI scanning energy consumption and carbon footprint of Radiology. Goal(s): To demonstrate the achievable savings in time and energy during clinical MRI scans. Approach: Power meters were connected to three clinical MRI scanners from different field strengths to collect power data while phantom scans were acquired with typical clinical sequences and a range of common acceleration methods. Results: The application of acceleration techniques resulted in decreased scan duration, energy consumption, and carbon footprint. Deep Learning (DL) acceleration emerged as the technique with the most savings. Impact: This research paves the way for adoption of high-efficiency MRI techniques, which promise to substantially lower the carbon footprint and scan duration associated with MRI exams.
Optimising magnetisation preparation for the 7T FLAIR contrast: simulations and experimental validation
Authors: Sleight Emilie , Klauser Antoine , Piredda Gian Franco , Grouiller Frédéric , Hilbert Tom , Van De Ville Dimitri
Published: November 2024

Motivation: At ultra-high field, magnetisation preparation should be adjusted to obtain an adequate FLAIR contrast. However, such optimisation of the pulse sequence and comparison between preparation types are missing. Goal(s): This work aimed to set a simulation framework to investigate the timing of the magnetisation preparation at 7T. T2 and double inversion recovery preparations were compared. Approach: Various preparation durations were investigated using simulations and measurements on healthy volunteers. Results: The image contrast obtained under simulation was experimentally validated. The T2-preparation gave the most promising contrast although the pulses were more prone to B0-inhomogeneity artefacts than the ones from the double inversion recovery preparation. Impact: We demonstrated that an adequate FLAIR contrast at 7T can be obtained by optimising magnetisation preparation. Simulations can be used to improve the sequence, such as optimising the magnetisation preparation and readout in terms of timings and flip angles.
Radiomics of voxelwise DCE-MRI TIC profiles map enables quantifying temporal and spatial hemodynamic heterogeneity in breast lesions
Authors: Liu Zhou , Sun Meng , Yao Bingyu , Wang Meng , Ren Ya , Yang Qian , Cui Wei , Zhang Na , Luo Dehong
Published: November 2024

Motivation: An effective approach that enables simultaneous quantification of spatial and temporal heterogeneity based on DCE-MRI is lacking. Goal(s): To develop a data-driven model-free approach to quantify spatial and temporal hemodynamic heterogeneity. Approach: We introduced radiomics analysis based on voxelwise mapping of DCE-MRI time-intensity-curve (TIC) profiles to quantify temporal and spatial hemodynamic heterogeneity and investigated its value in differentiating malignant and benign breast lesions. Results: Radiomics features and composition ratio of voxelwise TIC profiles showed good performance in differentiating malignant and benign breast lesions. Impact: We provide a novel data-driven model-free approach for visualizing and quantifying temporal and spatial hemodynamic heterogeneity simultaneously, which shows potential for a variety of clinical implications concerning individualized management of breast lesions.
Effects of Kidney Perfusion levels on Renal Stiffness and Fluidity measured with Tomoelastography in an MRI-compatible ex-vivo model
Authors: Castelein Johannes , Pamplona Carolina , Santos Marina Vidal dos , Armstrong-Jr Roberto , Moers Cyril , Dierckx Rudi , Borra Ronald , Sack Ingolf
Published: November 2024

Motivation: Tomoelastography allows for early detection of changes in the renal stiffness of various kidney pathologies. However, variations in tissue perfusion can have a strong impact on the assessment of renal stiffness. Goal(s): To characterize the effect of tissue perfusion on renal stiffness and tissue fluidity. Approach: Five ex vivo porcine kidneys were separately perfused in an MRI-compatible normothermic machine perfusion setup and simultaneously examined by Tomoelastography. Results: Our results show a strong positive correlation between increasing tissue perfusion and stiffness in the cortex and medulla of ex vivo porcine kidneys being observed after readily one minute of altered tissue perfusion. Impact: Stiffness is an essential factor in diagnosing renal fibrosis. When the renal vasculature is highly perfused, it can mimic increased stiffness associated with renal fibrosis. Our study emphasizes the strong dependency of renal stiffness and fluidity on perfusion.
MR SIGNATURE MATCHING (MRSIGMA) WITH ADAPTIVE MOTION LEARNING FOR ROBUST REAL-TIME 4D MRI ON A 1.5T MR-LINAC
Authors: Siddiq Syed , Murray Victor , Wu Can , Otazo Ricardo
Published: November 2024

Motivation: Real-time 4D MRI on the MR-Linac is still sensitive to respiratory motion baseline drifts. Goal(s): To further develop MRSIGMA for real-time adaptation to out-of-range anatomical changes during signature matching. Approach: The motion dictionary was continuously updated using a sliding window of stack-of-stars data and fast motion-resolved Movienet reconstruction. MRSIGMA with adaptive motion learning was implemented in real-time using an external computer connected to the MR-Linac and tested on a programmable 4D phantom and a patient with pancreatic cancer. Results: The adaptive motion learning approach was able to update the dictionary after 2 sliding window periods, which improved robustness of real-time volumetric motion tracking. Impact: MRSIGMA with adaptive learning would enable real-time volumetric motion tracking robust to respiratory motion baseline drifts and other anatomical changes on the MR-Linac for improved monitoring and adaptation of radiotherapy of tumors affected by respiratory motion.
Comparing k-space versus image domain loss functions in joint learning of sampling pattern and deep-learning reconstruction
Authors: Zibetti Marcelo , Regatte Ravinder
Published: November 2024

Motivation: Joint learning of sampling pattern (SP) and deep-learning (DL) reconstruction can have their loss functions in the k-space or image domain. It is not clear which approach is better. Goal(s): Investigate this question by comparing the results of both loss functions, exploiting the flexibility of k-space domain loss functions for joint learning. Approach: We modify the training of DL reconstructions to compare image or k-space domain losses. We tested on two DL networks and two different datasets, always using raw k-space as input. Results: The differences in image quality are very small, but there are visual differences in the learned SPs. Impact: This investigation shows that image loss is also a good option, but k-space loss is more flexible to control the shape of the SP. Interestingly, different learned SPs, with slightly different distributions of k-space samples, led to similar quality results.
Using digital reference objects to optimize advance reconstruction methods for abdominal DCE MRI in the presence of motion
Authors: Sakhardande Jayant , Velikina Julia , Samsonov Alexey , Schrauben Eric , Holmes James
Published: November 2024

Motivation: Concern over gadolinium contrast injections for research purposes limits in vivo testing of new imaging methods. An in-silica optimization strategy is needed when developing advanced reconstructions in the setting of free-breathing abdominal DCE MRI. Goal(s): Demonstrate a framework for testing performance of different reconstructions. Approach: A publicly available DRO was used to generate simulated free-breathing abdominal DCE k-space data. Data was then reconstructed using different reconstruction settings for MOCCO and SENSE. Results: This approach allowed head-to-head comparisons of different reconstruction methods as well as comparison with the ground truth data used to generate the DRO. Impact: The proposed testing approach allows researchers to test numerous combinations of acquisitions and reconstructions while having ground truth as a benchmark.
Automated Deep Learning-Based Magnetic Resonance Parkinsonism Index 2.0 in Early Parkinson’s Disease: A Longitudinal Study
Authors: Hartono Septian , Venkategowda Punith , S Madappa , Jerez Ricardo , Maréchal Bénédicte , Di Noto Tommaso , Ng Samuel Yong Ern , Chia Nicole Shuang Yu , Chung Yiu Cho , Gan Julian , Tan Louis Chew Seng , Tan Eng King , Chan Ling Ling
Published: November 2024

Motivation: There is a pressing need for accurate and reliable methods to track disease progression in patients presenting with early Parkinsonism. Goal(s): We aim to assess the utility of a fully automated deep learning-based method developed to estimate both MRPI 1.0 and 2.0 measures in a large, longitudinal, three time-point case-control cohort of patients presenting with early Parkinsonism. Approach: MRPI 1.0 and 2.0 measures were computed from 3D T1-weighted images using the Quantitative Brain Assessment Toolkit (QBAT, v2.1.0) research application. Results: MRPI 2.0 showed improved group differentiation and disease classification when compared to MRPI 1.0 in patients presenting with early Parkinsonism. Impact: Automated, deep learning-based MRPI 2.0 assessment may be used as quick tool to facilitate radiological screening, complementary to other quantitative MRI techniques such as quantitative susceptibility mapping and diffusion MRI, to track progression in Parkinson’s disease.
Temporal profile block-matching denoising enables free-breathing dynamic 19F lung MRI with sub 0.5 second acquisition time
Authors: Nguyen Truc , Huynh Khoi , Chung Sang , Yap Pew-Thian , Lee Yueh
Published: November 2024

Motivation: 19F pulmonary MRI is often used to characterize abnormalities in case of cystic fibrosis but its long scan time requires patients to hold their breath, which is uncomfortable and complicates acquisition. Goal(s): We introduce a denoising method to be used with fast 19F imaging that will enable free-breathing dynamic imaging. Approach: 12 subjects underwent both conventional breath-hold and fast free-breathing imaging. Temporal block-matching denoising was done for free-breathing images. Results: Our denoising method enables free-breathing dynamic 19F lung imaging. Images are recovered from the noise floor and show similar characteristics to conventional breath-hold imaging. Impact: Our denoising method enables free-breathing 19F dynamic lung imaging with sub 0.5 second acquisition time. Free-breathing imaging will increase patient comfort and potentially extend ventilation MRI use to more patients, including those with severe lung disease.
Removing Background Velocity Errors in PC-MRI with Optimized Spoiler Gradient Waveforms
Authors: Loecher Michael , Ennis Daniel
Published: November 2024

Motivation: Background velocity errors caused by eddy currents and mechanical oscillations in PC-MRI are a significant source of measurement error for which prospective corrections remain unavailable. Goal(s): To prospectively design spoiler gradient waveforms that reduce background velocity errors to levels generally considered irrelevant. Approach: A gradient optimization toolbox (GrOpt) was used in conjunction with a gradient impulse response to design error-minimizing waveforms. They were tested in a phantom and in 10 volunteers. Results: Background velocity errors were reduced by 84±10.4% with the gradient spoiler optimization and to levels below a clinically relevant threshold (0.4% Venc) in 96% of subjects. Impact: We used a gradient optimization (GrOpt) toolbox and the gradient impulse response function to prospectively design spoiler gradient waveforms that reduce background velocity errors in PC-MRI to levels below a clinically relevant threshold in 96% of subjects.
Concurrent optoacoustic tomography and magnetic resonance imaging of resting-state functional connectivity in the mouse brain
Authors: Gezginer Irmak , Chen Zhenyue , Deán-Ben Xosé Luís , Razansky Daniel
Published: November 2024

Motivation: Interpreting BOLD signals in fMRI studies is a challenging task due to their dependence on multiple factors. Goal(s): Multiparametric readouts from a recently developed hybrid magnetic resonance optoacoustic tomography system can offer unprecedented capabilities for studying the rodent brain in resting-state conditions. Approach: Simultaneously acquired multimodal functional data of mice were utilized to link hemoglobin resolved optoacoustic readouts to BOLD. Results: Multiparametric brain-wide activity were detected under resting-state condition for the first time. Revealed functional connectivity maps and brain networks showed high spatial overlap among the hemodynamic components. BOLD and total hemoglobin functional connectivity were found tightly correlated, compared to oxygenated- and deoxygenated-hemoglobin. Impact: Hybridization of optoacoustic tomography and MRI is a powerful multi-modal approach due to highly complementary contrasts and capabilities for functional neuroimaging. The more comprehensive functional readings provide unique capabilities for studying neurovascular and neurometabolic coupling mechanisms and related diseases.
The effect of valve annulus tracking on mitral valve regurgitation: A comparative in vitro study between ultrasound and 4D flow MRI
Authors: Kwon Minseong , Lee Juyeon , Park Sungho , Huh Hyungkyu
Published: November 2024

Motivation: Mitral valve regurgitation (MVR) is the most common heart valve diseases, but accurate quantification of MVR has been limited due to the dynamic motion of valves. Goal(s): We hypothesize that volumetric flow information by 4D flow MRI with the compensation of MV motion could address this challenge. Approach: MVR was measured using a simulated-in vitro model by comparing with actual flow from pump, ultrasound, and 4D flow MRI with/without a mitral registration algorithm. Results: PISA method overestimated MVR. 4D flow MRI without algorithm seems to have similar the amount of actual MVR, while it decreased with employing algorithm. Impact: Accurate quantification of regurgitation plays an important role for diagnosing patients with valvular diseases. This study would have a chance to measure accurate MVR quantification and quantify complex intracardiac blood flow using 4D flow MRI.
A numerical investigation of meander and solenoidal dipole antenna array configurations for 7T MR applications.
Authors: Bhosale Aditya , Ying Leslie , Zhang Xiaoliang
Published: November 2024

Motivation: Optimize dipole antennas for 7T MR applications. Goal(s): Enable compact 300MHz dipole structures for higher-channel arrays. Approach: Introduce a solenoidal dipole design and evaluate against meander designs using numerical simulations. Results: Analyze H-field efficiency, electric-field distributions, coupling, and Q-factors in multi-channel arrays. Impact: The introduction of a solenoidal dipole design overcomes limitations posed by meander structures, enabling shorter and compact 300MHz dipole antennas for 7T MR applications within higher-channel multi-channel arrays, positively impacting MR imaging efficiency and signal quality.
Pancreatic Fat Quantification in Human Diabetes and Its Relationship with β-Cell Reduction
Authors: Zhang Na , Liu Dingxia , Fu Caixia , Zhang Jiaxin , Zhang Ruonan , Hu Ke , Yang Yumei , Wang Baomin , Ma Jing , Chen Yi , Yang Runyue , Yao Xiuzhong , Li Xiaomu
Published: November 2024

Motivation: Patients with type 2 diabetes have more pancreatic fat, but its impact on β-cells is unclear. Goal(s): Our goal is to explore the impact of pancreatic fat on β-cells. Approach: We employed 6-point Dixon MRI to confirm the pancreatic fat fraction (PFF) in patients with type 2 diabetes. Histologic analysis was conducted to validate our findings and immunohistochemical staining was performed to observe changes in β-cells. Results: We found a negative relationship between β-cell mass and PFF in patients with type 2 diabetes. This suggested that the increased pancreatic fat observed in type 2 diabetes might contribute to reducing the number of β-cells. Impact: This study provided evidence that increased pancreatic fat in type 2 diabetes was associated with a decreased number of β-cells. These findings suggested targeting pancreatic fat accumulation could be a potential therapeutic approach for improving glycemic control in diabetic patients.
Quiet Fat-suppressed T1-weighted MRI by Dual-IR PETRA
Authors: Wang Yulin , Zeng Jie , Zhang Jichang , Zhu Yuliang , Ke Shiying , Niu Shengyang , Lin Lili , Yao Chendie , Wang Chengbo
Published: November 2024

Motivation: MRI produces considerable acoustic noise. PETRA sequence can solve this problem but has limited contrast. Goal(s): This study improves PETRA sequence by magnetization preparation to achieve widely used T1-weighted imaging with fat suppression and sound reduction. Approach: Double asymmetric adiabatic RF pulses are designed to invert aqueous tissues for T1-weighted contrast creation and invert lipidic tissues for fat suppression and combined with PETRA gradient trajectories. Results: The brain and knee experiments are conducted to verify the feasibility of the proposed sequence. The fat is decreased by above 70%. The gray-to-white matter contrast and knee cartilage visualization are enhanced compared with non-prepared PETRA sequence. Impact: The significantly reduced SPL of 67.4 dBA using limited gradient switching, providing better patient scanning comfort, can promote its acceptance to pediatric imaging. The double RF preparation design improves the limited contrast of PETRA.
Multimodal MR identifies the prefrontal cortex as central hub of stress-induced brain alterations in rats
Authors: Junker Carl-Lennart , Reinwald Jonathan , Sartorius Alexander , Weber-Fahr Wolfgang
Published: November 2024

Motivation: Chronic unpredictable mild stress (CUMS) is utilized to model depression-like symptoms in rodents. Although the prevalence of depression is twice as high in women, 97% of CUMS studies focused on male animals. Goal(s): We aimed to comprehensively phenotype the effect of CUMS in female rats using MRI. Approach: Thus, we assessed a CUMS-induced depression-like phenotype with various behavioral tests and multimodal MRI specifically in females. Results: We found prominent prefrontal and striatal volume loss, together with prefrontal glutamate reduction, and decreased top-down prefrontal control of the nucleus accumbens, corroborating the high sensibility of the PFC to chronic stress in the female population. Impact: We identified the prefrontal cortex as the central hub of chronic stress-induced changes in brain function in a female population of animals using multimodal MRI, thus creating a model for further investigation of distinct effects in possible treatments.
Bayesian methods accurately predict ADC bias resulting from clinical diffusion-encoding gradients: Validation through simulation studies.
Authors: Blackledge Matthew , Thrussell Imogen , Yu Sheng
Published: November 2024

Motivation: Measurement of ADC in body DWI is typically assumed to be isotropic and therefore the use of single-direction diffusion encoding imaging is commonplace. Estimation of induced bias by this assumption is needed. Goal(s): To determine whether Bayesian estimation of ADC measurement bias from DTI data suffers from any systematic errors and thus can be used reliably in clinical datasets. Approach: We use simulation studies over a range of true fractional-anisotopy (FA), signal-to-noise ratio (SNR) and mean-diffusivity parameters, and investigate the accuracy of Bayesian estimation approaches. Results: Bayesian estimation of ADC bias appears accurate over the range of tested parameters. Impact: Accurate estimation of ADC bias from single-direction diffusion-encoding schemes is possible using Bayesian approaches in combination with data acquired using a multi-directional diffusion-encoding scheme. This enables pixel-wise estimation of bias and could negate the need for directly acquiring paired datasets.
Physiological Interpretation of the AUC Ratio for Hyperpolarized [1-13C]-Pyruvate
Authors: Boyce Ryan , Harlan Collin , Wang Qing , Bankson James
Published: November 2024

Motivation: The prevalence of the use of AUC ratio as a metric of anaerobic respiration in hyperpolarized pyruvate studies motivates a careful examination of its physiological interpretation. Goal(s): We seek to characterize the lactate to pyruvate AUC ratio as a surrogate for aerobic glycolysis in cancer cells. Approach: A simplified three-compartment kinetic model is proposed and analyzed. The AUC ratio is found from the model for interpretation. Results: The simplified three-compartment model is shown to produce equivalent time curves to the full model. The AUC ratio, parametrized by the simplified model, varies non-linearly with the rate of intracellular lactate production. Impact: The efficacy of hyperpolarized pyruvate as a probe of tumor metabolism relies on an accurate and reproducible quantification and interpretation of acquired signal. We critically examine one of the most commonly used methods of signal interpretation in hyperpolarized pyruvate studies.
Cutting edge: Anatomie - Woher? Wohin?
Authors: Waschke Jens
Published: November 2024

Was haben Goethe, Leonardo da Vinci mit Aristoteles und Empedokles gemein? Warum haben die Humboldt-Brüder Leichen, Gorg Büchner die Nerven von Fischen seziert? Das Buch soll Ihnen erklären, warum Philosophen, Künstler und Wissenschaftler seit 2500 Jahren anatomische Studien betrieben haben. Und was Anatomie vielleicht sogar für eine Gesellschaft, ganz sicher aber für Sie und ihre Gesundheit bedeutet. Ich - bin übrigens Anatom. Was auch sonst?
Logoların Temsil, Saygınlık ve Kimliklendirmedeki Rolü
Authors: Atasoy Seda Nur
Published: November 2024

Bu bölümde, logoların markalar için temsil, saygınlık ve kimlik kazandırmadaki kritik rolü ele alınmaktadır. Bir marka veya kurumun görsel yüzü olan logolar, yalnızca birer sembol olmaktan öte, tüketiciler nezdinde güven inşa eden ve marka bağlılığını pekiştiren birer iletişim aracıdır. Tarihsel süreç içerisinde semboller ve işaretler üzerinden gelişen logolar, günümüzde bir markanın değerini, kültürel arka planını ve ideallerini aktaran görsel temsiller olarak ön plana çıkmaktadır. Bu çalışmada, logoların tüketici algısını nasıl şekillendirdiği, kurumsal saygınlığı nasıl desteklediği ve bir markanın kimliğini nasıl tanımladığı çeşitli örnekler üzerinden ele alınmaktadır. Ayrıca, logoların kültürlerarası iletişimde evrensel bir dil oluşturma kapasiteleri ve dijital çağda değişen işlevleri incelenmektedir. Bölüm, logoların görsel dilde anlam yüklü bir araç olarak markaların saygınlığını nasıl güçlendirdiğine ve kimliklendirmedeki rolüne dair ayrıntılı bir bakış sunarak, kurumsal iletişim ve grafik tasarım alanına katkıda bulunmaktadır.
PEMANFAATAN BIOTEKNOLOGI DALAM PEMBUATAN TAPE KETAN SEBAGAI PRODUK UNGGULAN LOKAL
Authors: Syahrir Maulidyah
Published: November 2024

Ketan hitam mengandung komponen fenolik yang memiliki sifat antioksidan, dan tape ketan merupakan produk fermentasi tradisional yang kaya akan nilai budaya di Indonesia. Proses pembuatan tape ketan, yang melibatkan fermentasi oleh mikroorganisme seperti ragi, dapat dioptimalkan melalui penerapan bioteknologi untuk meningkatkan kualitas, stabilitas, dan nilai ekonomis produk. Metode produksi konvensional yang tidak terstandarisasi sering mengakibatkan kualitas tape yang bervariasi. Oleh karena itu, program pengabdian masyarakat ini bertujuan untuk memberikan pengetahuan dan keterampilan kepada masyarakat dalam menerapkan bioteknologi sederhana dalam produksi tape ketan. Melalui pelatihan, masyarakat dapat memahami prinsip fermentasi dan mengembangkan variasi produk baru. Hasil dari program ini menunjukkan peningkatan kualitas tape ketan yang dihasilkan, termasuk rasa, tekstur, dan masa simpan yang lebih baik. Diversifikasi produk dan penggunaan teknik pemasaran modern juga meningkatkan daya saing tape ketan di pasar. Secara keseluruhan, program ini berdampak positif terhadap peningkatan pendapatan dan kesejahteraan ekonomi masyarakat lokal.
Kata kunci : tape, fermentasi, bioteknologi, produk,lokal
Optimalisasi Pengendalian Persediaan Material Lithos: Studi Perbandingan Metode EOQ dan POQ untuk Efisiensi Biaya
Authors: Octavieka Yoel Agung , Pratama Ibnu Lukman
Published: November 2024

PT. X menghadapi tantangan dalam pengelolaan persediaan material lithos yang digunakan sebagai bahan utama untuk packaging pelumas, sering kali mengalami kekurangan atau kelebihan stok yang berpotensi mengganggu operasional. Penelitian ini bertujuan untuk membandingkan efektivitas dua metode pengendalian persediaan, yaitu Economic Order Quantity (EOQ) dan Period Order Quantity (POQ), dalam meminimalkan biaya persediaan dan memastikan kelancaran produksi. Data throughput material lithos pada tahun 2022 dan hasil forecasting tahun 2023 dianalisis menggunakan kedua metode ini untuk menentukan metode yang paling efisien. Hasil penelitian menunjukkan bahwa metode EOQ lebih optimal dalam meminimalkan Total Inventory Cost (TIC) dibandingkan POQ, baik pada tahun 2022 maupun dalam proyeksi tahun 2023. Implementasi metode EOQ direkomendasikan untuk pengelolaan persediaan material lithos di PT. X guna meningkatkan efisiensi biaya dan operasional perusahaan.
Analisis Sosial Ekonomi yang Mempengaruhi Kesejahteraan Rumah Tangga di Jawa Timur dengan Analisis Faktor
Authors: Syabrina Devynta , Sahira Naswa , Wulandari Sri Pingit
Published: November 2024

Penelitian ini mengkaji faktor-faktor sosial ekonomi yang memengaruhi kesejahteraan rumah tangga di Jawa Timur dengan menggunakan Analisis Komponen Utama (PCA) dan analisis faktor. Data sekunder diperoleh dari Badan Pusat Statistik (BPS) untuk 38 kabupaten/kota di Jawa Timur tahun 2023. Delapan variabel yang dianalisis meliputi: kepemilikan tanah, kepemilikan rumah, tingkat pengangguran terbuka (TPT), tingkat partisipasi angkatan kerja (TPAK), persentase kemiskinan, akses terhadap air minum layak, penerima Kartu Keluarga Sejahtera (KKS), dan penerima Program Keluarga Harapan (PKH). Analisis statistik deskriptif, pengujian asumsi (distribusi normal, uji Bartlett, uji KMO, dan korelasi anti-image), serta PCA dilakukan untuk mengidentifikasi komponen utama dan hubungan antar faktor. Hasil penelitian menunjukkan dua komponen utama: "Stabilitas Ekonomi dan Infrastruktur" yang mencakup variabel seperti kepemilikan tanah dan rumah, tingkat pengangguran, partisipasi angkatan kerja, akses air bersih, dan penerima KKS; serta "Kerentanan Sosial dan Bantuan" yang meliputi persentase kemiskinan dan penerima PKH. Kedua komponen ini menjelaskan 78,1% variansi faktor kesejahteraan rumah tangga. Penelitian ini memberikan wawasan untuk meningkatkan kesejahteraan rumah tangga melalui kebijakan terpadu yang berfokus pada stabilitas ekonomi dan dukungan sosial. Temuan ini juga menekankan pentingnya optimalisasi program bantuan sosial dan strategi yang lebih terarah untuk meningkatkan kualitas hidup di Jawa Timur.
Hubungan Stres Akademik Dengan Kecemasan Masa Depan pada Mahasiswa Ditinjau Dari Jenis Kelamin
Authors: Seilyana Zahrotul Mahmudah  , Salim Agus , Yunita Setiyani Subardjo Ratna
Published: November 2024

Penelitian ini bertujuan untuk meneliti penerapan pendekatan Culturally Responsive Teaching dalam pembelajaran pendidikan agama islam di sekolah. CRT merupakan pendekatan pembelajaran yang menekankan pengakuan dan pengintegrasian keanekaragaman budaya, latar belakang, dan pengalaman siswa dalam proses pembelajaran. Studi ini menggunakan metode penelitian kualitatif dengan melibatkan peserta didik dari berbagai latar belakang budaya. Data dikumpulkan melalui observasi kelas selama kegiatan belajar mengajar berlangsung dan wawancara. Integrasi CRT dalam pembelajaran PAI dapat membantu menciptakan lingkungan pembelajaran yang inklusif, mempromosikan pemahaman lintas budaya, dan meningkatkan kemampuan belajar peserta didik. Studi ini juga memberikan pandangan yang lebih komprehensif tentang pentingnya mengakui dan merespons keanekaragaman budaya dalam konteks pendidikan agama, yang pada gilirannya dapat meningkatkan kualitas pendidikan di sekolah.
Analisis Kebijakan Pendidikan Tentang Rancangan Undang-Undang Sistem Pendidikan Nasional (RUU Sisdiknas) Tahun 2022
Authors: Rendi Muhamad Yani  , Jejen Musfah  , Hasyim Asy’ari  , Maftuhah
Published: November 2024

Penelitian ini adalah analisis mengenai Rancangan Undang-undang Sistem Pendidikan Nasional (RUU Sisdiknas) yang di inisiasi oleh Kemendikbudristek RI pada tahun 2022. Penelitian ini ingin mengetahui bagaimana analisis proses kebijakan Pendidikan dan analisis isi kebijakan Pendidikan dari RUU Sisdiknas tahun 2022. Metode penelitian ini adalah metode kualitatif dengan menggunakan analisis proses dan analisis isi kebijakan Pendidikan dalam bentuk studi dokumen. Dokumen-dokumen yang dikumpulkan menjadi data penelitian ini adalah draft RUU Sisdiknas tahun 2022, draf naskah akademik RUU Sisdiknas tahun 2022, draf sosialisasi Kemendikbudristek RI sepanjang tahun 2022 serta pandangan-pandangan yang komprehensif dari para ahli Pendidikan, akademisi, praktisi Pendidikan, dan unsur-unsur masyarakat yang berkepentingan dalam dunia Pendidikan. Dari penelitian ini dapat diketahui beberapa polemik yang dimunculkan sejak di usulkannya RUU ini oleh Kemendikbudristek RI pada tahun 2022, dimana RUU ini sudah masuk Badan Legislasi (Baleg) DPR RI serta sudah masuk daftar Program Legislasi Nasional (Prolegnas) prioritas tahun 2023. Namun berkat kritikan dan penolakan dari berbagai pihak, RUU ini kemudian dicabut kembali dari Prolegnas prioritas. Adapun polemik-polemik tersebut adalah: (1) Polemik penyususnan RUU Sisdiknas, (2) Wacana Omnibuslaw sistem Pendidikan nasional, (3) Tidak ada Peta Jalan Pendidikan Nasional, (4) Hilangnya Tunjangan Profesi Guru, dan (5) Hilangnya frasa madrasah.
Klasifikasi Shellcode Dengan Machine Learning Berbasis Klasifikasi Biner
Authors: Naufal Semendawai Jaka , Stiawan Deris , Pahendra Iwan
Published: November 2024

Internet dapat menghubungkan satu orang dengan orang lain dengan menggunakan perangkat masing-masing. Internet sendiri memiliki dampak positif dan negatif. Salah satu contoh dampak negatif dari internet adalah adanya malware yang dapat mengganggu atau bahkan merusak perangkat atau penggunanya; itulah mengapa keamanan siber diperlukan. Banyak cara yang dapat dilakukan untuk mencegah atau mendeteksi malware. Salah satunya adalah dengan menggunakan teknik machine learning. Dataset pelatihan dan pengujian untuk eksperimen ini berasal dari dataset UNSW_NB15. K-Nearest Neighbour (KNN), Decision Tree, dan Naïve Bayes diimplementasikan untuk mengklasifikasikan apakah sebuah record pada data testing merupakan serangan Shellcode atau non-Shellcode. Classifier KNN, Decision Tree, dan Naïve Bayes mencapai tingkat akurasi masing-masing sebesar 96.82%, 97.08%, dan 63.43%. Hasil dari penelitian ini diharapkan dapat memberikan wawasan mengenai penggunaan machine learning dalam mendeteksi atau mengklasifikasikan malwares atau jenis serangan siber lainnya
Hubungan Lama Menderita Diabetes Melitus Dengan Kualitas Hidup pada Pasien di Rumah Sakit Royal Prima Medan
Authors: Br. Sitorus Irma Yeni , Wienaldi Wienaldi , Darmadi Suhartina
Published: November 2024

Diabetes mellitus merupakan salah satu gangguan pada sistem endokrin. Kualitas hidup yang kurang baik pada pasien diabetes melitus akan menyebabkan terjadinya penurunan dalam selfcare yang merusak kontrol glikemik, meningkatkan risiko komplikasi, dan memperburuk keadaan dari waktu ke waktu. Penelitian ini bertujuan untuk mengetahui hubungan antara lama menderita diabetes melitus dengan kualitas hidup pada pasien di Rumah Sakit Royal Prima Medan. Jenis penelitian adalah kuantitatif korelasional dengan metode pendekatan cross sectional. Populasi penelitian adalah seluruh penderita diabetes melitus yang melakukan chek up rutin di Rumah Sakit Royal Prima. Besar sampel sebanyak 50 orang penderita diabetes melitus menggunakan consecutive sampling. Analisis data dilakukan secara univariat dan bivariat dengan uji statistik chi square. Berdasarkan hasil penelitian dapat dinyatakan bahwa ada hubungan usia (p=0,026), jenis kelamin (p=0,005), status pernikahan (p=0,046), pekerjaan (p=0,036), penghasilan (p=0,016), dan lama menderita diabetes melitus (p=0,001) terhadap kualitas hidup pasien yang signifikan di Rumah Sakit Royal Prima Medan. Disarankan pada petugas kesehatan agar melakukan penyuluhan mengenai pentingnya aktivitas fisik untuk mencegah diabetes melitus, dan mengadakan kegiatan untuk mengajak masyarakat aktif beraktivitas fisik seperti senam sehat prolanis di setiap minggu
La cultura organizacional en las MiPYMES del sector artesanal en el cantón Chimbo, provincia Bolívar, Ecuador
Authors: Garofalo Ronquillo Edgar Fabricio , Torres Cadena Juan Pablo
Published: November 2024

Este estudio exploró las características de la cultura organizacional en las Micro, Pequeña y Mediana Empresa (MiPYMES) del sector artesanal del cantón Chimbo, Ecuador, con el objetivo de identificar los rasgos específicos de dicha cultura en estas empresas. La metodología que se aplicó fue de enfoque cuantitativo y descriptivo, utilizando encuestas estructuradas para recolectar datos sobre la percepción de los empleados respecto a la misión, adaptabilidad, participación y consistencia organizacional. Los resultados mostraron una predominancia de empleados mayores de 50 años y una fuerza laboral mayoritariamente masculina. Aunque los empleados valoran la autonomía y el trabajo en equipo, existió una percepción de insuficiente inversión en el desarrollo profesional y de un liderazgo menos colaborativo. A pesar de ser percibidas como adaptables e innovadoras, las empresas enfrentaron limitaciones debido a la falta de recursos financieros y técnicos. Se concluye que fortalecer la comunicación interna, la inversión en formación continua y el acceso a recursos es clave para mejorar la competitividad de estas MiPYMES.
Investigation of the Interaction Between Physical Activity Levels and Quality of Life of Desk-Based Staff in a State University: A Cross-Sectional Study
Authors: Yılmaz Dursun Alper
Published: November 2024

Aim: This study aims to evaluate the relationship between physical activity levels and the quality of life of rectorate staff who have been working at a state university for at least one year.

Method: The study, conducted from June 2021 to January 2022, included adults aged 30-65 who were predominantly sedentary in their occupational roles, had a body mass index greater than 18.5 kg/m², and had been employed at the state university rectorate for at least one year. A total of 60 participants were enrolled. The International Physical Activity Questionnaire, the SF-36 (Health Form-36) Quality of Life Scale, and the TANITA MC-780 Black Bioelectrical Impedance Analysis (BIA) for measuring body mass index were utilized as assessment instruments.

Results: The examination of the sub-dimensions of the SF-36 revealed the following mean scores: physical function was 69.43±18.65, physical role difficulty was 74.17±35.04, emotional role difficulty was 73.45±28.21, pain was 78.42±20.43, energy/vitality was 56.25±6.61, social functioning was 71.71±20.23, mental health was 49.2±7.33, and general health was 50.13±12.48. The Total Physical Activity Score was 2876.02±1547.95. No statistically significant correlation was observed between the participants' physical activity levels and their overall quality of life (p>0.05). However, a significant difference was detected between physical function and gender (p
Why guidelines fail: on consequences of the false dichotomy between global and local knowledge in health systems
Authors: Sadki Reda
Published: November 2024

Global health continues to grapple with a persistent tension between standardized, evidence-based interventions developed by international experts and the contextual, experiential local knowledge held by local health workers. This dichotomy – between global expertise and local knowledge – has become increasingly problematic as health systems face unprecedented complexity in addressing challenges from climate change to emerging diseases.
What luck
Authors: Day Adam
Published: November 2024

There’s a brilliant essay by Michael Nielsen from 2009 which predicted that disruption in academic publishing was imminent. Of course, we’re still here, so there was no existential crisis, but I think it’s still worth a read, even now. Reflecting on Nielsen’s essay in 2016, Michael Clarke observed that the web was created at CERN for the purpose of communicating scientific research.
Optimization Model for Climatic Change Impact on the Water Quality of Al-Hilla River, Iraq
Authors: Hassan Dinar Haibet , Atheer Zaki Al-Qaisi  , Hadeel Kareem Jasim
Published: November 2024

This study presents an advanced optimization model to assess the impacts of climate change on water quality in the Al-Hilla River. To reduce uncertainties associated with climate change projections and quantify the river's water quality response, a novel model of the river system is developed, with the objective function integrated into optimization theory. Water quality simulations for different regions of the river system are performed using the QUAL2K model, while the Ant Colony Optimization (ACO) method is applied to optimize the model. Additionally, the study investigates the effects of temperature and DO variations on microbial populations and the self-purification capacity of the water body. The results indicate that all climate change scenarios lead to a decline in water quality, with significant reductions in dissolved oxygen (DO) levels, even under safe discharge conditions. The study demonstrates that the proposed technique can identify optimal solutions more efficiently, contributing to faster and more reliable decision-making in water quality management. Also, the findings reveal that both temperature and DO significantly influence microbial composition and self-purification processes, with higher temperatures and DO levels improving self-purification efficiency. These insights enhance our understanding of the complex interactions between environmental factors and water quality, offering a valuable foundation for future water management strategies aimed at mitigating the effects of climate change.
Tijauan Yuridis Terhadap Penerapan Undang – Undang Narkotika Dalam kasus Teddy Minahasa
Authors: Vehrial Vahzrianur  , Samudra Farasi Putra  , Nabila Alya Husna  , Muhamad Revanza Solihin  , Herli Antony
Published: November 2024

Pelanggaran narkoba adalah tindakan yang dilarang oleh undang-undang terkait narkoba. Narkotika adalah zat atau obat yang berasal dari tumbuhan atau bukan tumbuhan yang dapat menimbulkan ketergantungan fisik atau psikis pada pemakainya. Pelanggaran narkoba umumnya melibatkan penggunaan, penyalahgunaan, distribusi, produksi atau kepemilikan narkoba tanpa izin dari otoritas yang berwenang. Teddy Minahasa diduga menjual barang bukti seberat 5 kilogram dalam kasus narkoba, dan informasi keterlibatannya dalam peredaran barang bukti sudah dihimpun penyidik. Oleh karena itu Kejaksaan Agung harus memiliki hukuman yang lebih berat daripada para terdakwa lainnya. Permohonan jaksa tersebut dirinci dalam Pasal 55 KUHP yang melanggar Pasal 114 ayat 2 UU No 35 Tahun 2009 tentang Narkotika, dan digabungkan dengan Pasal 55 ayat 1 ayat 1 KUHP.
PENERAPAN PERLINDUNGAN KONSUMEN TERHADAP NASABAH PT. BANK SYARIAH INDONESIA DALAM KASUS KEBOCORAN DATA NASABAH
Authors: Vanesha Marcelliana  , Salsabila Muthia Zahra  , Ninda Nur Adzani  , Hanif Nur Massaid  , Nurhasna Badriyyah  , Raina Benita  , Moreno sukarto  , Choirunisa Nur Fitriani  , T. Alief Rizky Bayhaqi
Published: November 2024

Bank merupakan lembaga keuangan yang berperan penting bagi perekonomian Indonesia pada masa ini, kegunaan perbankan semakin meninggi karena semua dapat dilakukan menggunakan Handphone, Internet Banking, Mesin ATM, dan Teller di kantor cabang bank. Dari mulai kebutuhan sehari sehari dan menggunakan untuk transaksi dengan sesama pengguna bank yang sama atau yang lainnya. Etisnya, sudah seharusnya lembaga perbankan tersebut menjaga data privasi para nasabah yang menggunakan layanan mereka. Namun, tidak dapat dipungkiri adanya kasus kebocoran data yang salah satunya dialami oleh PT. Bank Syariah Indonesia dan tentunya melanggar prinsip data security, data privasi, dan etika. Adanya motif pencurian data menyebabkan hilangnya kerahasiaan, privasi, ketersediaan, dan integritas terhadap PT. Bank Syariah Indonesia serta menyebabkan kerugian baik berupa materiil maupun non materiil. Penelitian ini bertujuan untuk penerapan perlindungan hukum bagi konsumen PT. Bank Syariah Indonesia serta tanggung jawab pelaku usaha terhadap konsumen pada pelayanan perbankan pada PT. Bank Syariah Indonesia. Dengan mengangkat masalah ini diharapkan agar kita semua dapat lebih sadar akan risiko serangan siber yang mengancam industri perbankan, termasuk perbankan syariah.
Konsepsi Tangkisan Atau Bantahan Sebagai Hak Penerbit Surat Berharga
Authors: Akbar Syahru Rama  , Faquh Andy Antono  , Sumriyah Sumriyah
Published: November 2024

In carrying out its obligations to issue marketable securities, sometimes there are some mistakes that are actually unintentional by the issuer, such as in writing the nominal amount, date, etc. where the issuer realizes that his mistakes after the issuance of the marketable securities can certainly harm the issuer, then the issuer can make rebuttal. This study aims to find out how the role of countermeasures or countermeasures in protecting mistakes made by marketable securities. Based on the research results, it is known that countermeasures or rebuttal can be a special right of the issuer of marketable securities because it can protect the issuer of securities from not paying for the marketable securities issued.
PERLINDUNGAN HUKUM TERHADAP KONSUMEN YANG DIRUGIKAN DALAM KEGIATAN TRANSAKSI ONLINE DI SITUS BELANJA SHOPEE
Authors: Raudhya Alfira  , Sarah Sabrina Umboh  , Daffarel Derbi Syachrez  , Erlando Bagus Nugroho  , Carla Arletta  , Marsh Ardi Purnama  , Muhammad Rasyiid Herdiansyah
Published: November 2024

Internet  adalah suatu  akses yang sangat diminati  oleh orang-orang  di seluruh dunia. Di dalam  kehidupan  sehari-hari,  internet  digunakan oleh  manusia, salah satunya adalah jual-beli. Namun  demikian,  permasalah  yang  muncul  dari  jual  beli  online  sangat  beragam,  mulai  dari keamanan data diri hingga respon penjual yang kurang peka terhadap keluhan yang disampaikan pembeli.  Berkaitan dengan masalah  yang ada, tentunya pelaku  usaha  harus responsive,  karena respon atau  tanggung jawab  pelaku  usaha terhadap  keluhan  konsumen memiliki dampak besar bagi toko online atau online shop  itu sendiri.
 
Perkembangan hukum bisnis saat ini mengalami perkembangan yang sangat pesat. Selain itu,  perkembangan teknologi juga kemajuan dan hukum harus mengikuti perkembangan zaman. Di  Indonesia  mulai  berkembang istilah-istilah  suatu perbuatan  yang disebut transaksi jual-beli secara  online.  Mungkin  itu  akan  terjadi  menimbulkan  masalah  hukum.  Di  era  yang  sudah modern  ini,  banyak  konsumen  yang  lebih  memilih untuk  berbelanja dan melakukan transaksi jual-beli  melalui internet agar lebih  memudahkan, salah satunya melalui  situs Belanja Shopee. Meskipun,  pemerintah  dan  pihak  shopee  selaku  pelaku  usaha     telah  memberikan  jaminan mengenai   hak  konsumen  dalam  Undang-Undang,  faktanya  konsumen  yang  haknya  sering dikesampingkan  oleh pelaku usaha  masih banyak sehingga membuat konsumen merasa dirinya dirugikan pada saat bertransaksi di situs Shopee.Perlindungan  hukum  terhadap  konsumen  dalam  transaksi  jual-beli  online,  diperlukan untuk mendapatkan penegasan tanggung jawab sehubungan dengan praktik jual-beli online serta masalah  wanprestasi yang  disebabkan oleh  pelaku usaha.  Sejauh  mana peran marketplace  dan pelaku usaha ikut bertanggung jawab atas kerugian wanprestasi yang diderita konsumen. Shopee merupakan  salah satu  perusahaan yang mengubah  proses bisnisnya  melalui e-commerce,  yang berfokus   Pada   bidang   jual-beli   online.   Sehubungan   dengan   undang-undang  perlindungan konsumen  di  Indonesia,  telah  diatur  dalam  Undang-Undang  Nomor  8  Tahun  1998  Tentang Perlindungan Konsumen. Transaksi e-commerce memberikan kemudahan bagi konsumen dalam beraktifitas penjualan atau pembelian barang dan berdasarkan kebutuhan pelanggan pada saat itu
Efektifitas Perlindungan Hukum Pemegang Saham Dibawah 1/10 Dalam Mekanisme Pelaksanaan Gugatan Derivative Action
Authors: Imam Hakim Masyhuri  , Wasiatun Wasiatun  , Sumriyah Sumriyah
Published: November 2024

PT as a legal entity in carrying out legal actions must go through its management. Without a legal entity it will not work. The relationship between the directors and the company apart from being based on a working relationship, the directors also have a fiduciary relationship with the company. The Board of Directors has a fiduciary position in the company. Regarding the losses suffered by the company, both violations suffered by the company, whether violations of fiduciary obligations, ultra vires, or other mistakes committed by members of the board of directors, the shareholders of the company concerned have the right to file a derivative action (derivative action or derivative suit) against the members of the board of directors.
Responsibility for the decision of the lawsuit is borne by the company. In addition, the obstacle that is often encountered in this case is that lawsuits that have been submitted to the court are often passive in handling them. An error or omission that results in a loss within the company, as the basis for a derivative lawsuit, has no clear criteria. This ambiguity results in it being difficult to qualify that the actions of the Directors or Commissioners have occurred by mistake or negligence, so shareholders can also take part in dealing with these problems when the company they run suffers losses caused by the Directors or Commissioners. The method used in this study is normative juridical with a case approach and statutory approach. So the purpose of our research is to find out how the legal protection of shareholders against companies is through Derivative Action lawsuits.