bluuebunny/crossref_metadata_2025 huggingface dataset:
Novel applications of diagnostic X-rays in activating a clinical	photodynamic drug: Photofrin II through X-ray induced visible luminescence from	"rare-earth" formulated particles
Authors: Abliz Erkinay , Collins Joshua E. , Bell Howard , Tata Darrell B.
Published: November 2024

Introduction: In this communication we report on a novel non-invasive methodology in utilizing "soft" energy diagnostic X-rays to indirectly activate a photo-agent utilized in photodynamic therapy (PDT): Photofrin II (Photo II) through X-ray induced luminescence from Gadolinium Oxysulfide (20 micron dimension) particles doped with Terbium: Gd $_{2}$ O $_{2}$ S:Tb. Photodynamic agents such as Photo II utilized in PDT possess a remarkable property to become preferentially retained within the tumor's micro-environment. Upon the photo-agent's activation through (visible light) photon absorption, the agents exert their cellular cytotoxicity through type I and type II pathways through extensive generation of reactive oxygen species (ROS); namely, singlet oxygen $^{1}$ O $_{2}$ , superoxide anion O $_{2}^{-}$ , and hydrogen peroxide H $_{2}$ O $_{2}$ , within the intra-tumoral environment. Unfortunately, due to shallow visible light penetration depth (∼ 2 mm to 5 mm) in tissues, the current PDT strategy has largely been restricted to the treatment of surface tumors, such as the melanomas. Additional invasive strategies through optical fibers are currently utilized in getting the visible light into the intended deep seated targets within the body for PDT.

Methods: X-ray induced visible luminescence from Gd $_{2}$ O $_{2}$ S:Tb particles were spectroscopically characterized, and the potential in-vitro cellular cytotoxicity of Gd $_{2}$ O $_{2}$ S:Tb particles on human glioblastoma cells (due to 48 Hrs Gd $_{2}$ O $_{2}$ S:Tb particle exposure) was screened through the MTS cellular metabolic assay. In-vitro human glioblastoma cellular exposures in presence of Photo II with Gd $_{2}$ O $_{2}$ S:Tb particles were performed in the dark in sterile 96 well tissue culture plates, and the corresponding changes in the metabolic activities of the glioblastoma due to 15 minutes of (diagnostic energy) X-ray exposure was determined 48 Hrs after treatment through the MTS assay.

Results: Severe suppression (> 90% relative to controls) in the cellular metabolic activity of human glioblastoma was measured due to the treatment of clinically relevant concentrations of 20 μg/ml Photo II, with Gd $_{2}$ O $_{2}$ S:Tb particles, and (120 kVp) diagnostic X-rays. Taken together, the in-vitro findings herein provide the basis for future studies in determining the safety and efficacy of this non-invasive X-ray induced luminescence strategy in activating photo-agent in deep seated tumors.
Computer-aided classification of optical images for diagnosis of	osteoarthritis in the finger joints
Authors: Zhang Jiang , Wang James Z. , Yuan Zhen , Sobel Eric S. , Jiang Huabei
Published: November 2024

This study presents a computer-aided classification method to distinguish osteoarthritis finger joints from healthy ones based on the functional images captured by x-ray guided diffuse optical tomography. Three imaging features, joint space width, optical absorption, and scattering coefficients, are employed to train a Least Squares Support Vector Machine (LS-SVM) classifier for osteoarthritis classification. The 10-fold validation results show that all osteoarthritis joints are clearly identified and all healthy joints are ruled out by the LS-SVM classifier. The best sensitivity, specificity, and overall accuracy of the classification by experienced technicians based on manual calculation of optical properties and visual examination of optical images are only 85%, 93%, and 90%, respectively. Therefore, our LS-SVM based computer-aided classification is a considerably improved method for osteoarthritis diagnosis.
Estimasi stok karbon di atas permukaan pada ekosistem mangrove di Salo Sumbala Muara Badak Kutai Kartanegara sebagai upaya mitigasi perubahan iklim
Authors: Diana Rita , Matius Paulus , Yolanda Resvita
Published: November 2024

Mitigasi perubahan iklim merupakan suatu kegiatan usaha untuk mengurangi resiko peningkatan emisi gas rumah kaca yang ada di atmosfer, gas dapat muncul secara alami di lingkungan dan dapat pula muncul akibat aktivitas manusia. Peran hutan sebagai penyerap dan penyimpan karbon sangat penting dalam mengatasi masalah efek gas rumah kaca yang mengakibatkan pemanasan global. Hutan mangrove mampu menyimpan karbon sebanyak 3-5 kali dari hutan daratan lahan kering. Penelitian ini bertujuan untuk mengetahui simpanan karbon dan serapan karbon di Salo Sumbala, Kecamatan Muara Badak, Kabupaten Kutai Kartanegara, Provinsi Kalimantan Timur. Pengambilan data di lokasi menggunakan metode transek sepanjang 125 meter dan plot lingkaran. Secara keseluruhan terdapat 18 plot pengamatan yang terbagi dari 3 titik lokasi untuk memperoleh data jenis-jenis mangrove, pengukuran diameter dan tinggi pohon pada vegetasi semai, pancang, pohon dan necromass. Hasil pengukuran stok karbon pada lokasi 1 memiliki stok karbon sebesar 88,23 ton/ha, lokasi 2 memiliki stok karbon 87,17 ton/ha dan lokasi 3 memiliki stok karbon sebesar 52,24 ton/ha. Dari hasil penelitian pada lokasi 1 mampu menyerap CO2 sebesar 324,16 ton/ha, pada lokasi 2 mampu menyerap CO2 sebesar 319,14 ton/ha dan lokasi 3 mampu menyerap CO2 sebesar 191,57 ton/ha.
Підходи до моніторингу та оцінки ефективності системи мотивації студентської молоді до практик здорових моделей харчування
Authors: Лепканич Анна Олександрівна , Миронюк Іван Святославович
Published: November 2024

Вступ. Мета дослідження – визначити та описати основні підходи до формування системи моніторингу та оцінки ефективності системи мотивації студентської молоді до практик здорових моделей харчування в сучасних умовах. Методи та матеріали. У дослідженні було використано результати попередніх досліджень та застосовувалася методологія, яка рекомендована для систем моніторингу та оцінки програм і проектів соціальної сфери. Застосовано бібліосемантичний метод, метод концептуального моделювання та загальнонаукові методи аналізу, синтезу, порівняння та узагальнення. Дослідження проведено на засадах системного підходу. Результати. Визначено суб’єкт та об’єкт моніторингу та оцінки ефективності розробленої системи мотивації для внутрішньої система моніторингу та оцінки, яка повинна впроваджуватися безпосередньо на рівні закладу вищої освіти. Методика проведення програми моніторингу та оцінки запропонованої системи мотивації зводиться до відслідковування обов’язкових елементів, що визначають ефективність етапів її проведення: залучені ресурси, процес реалізації, отримані результати, наслідки та вплив. До індикаторів ресурсів в моделі системи мотивації входять матеріально-технічний, інформаційний та людський внесок. Індикатори наслідків і впливу розробляються для усієї системи в цілому. Запропоновано концептуальні підходи до розробки і впровадження програми моніторингу та оцінки системи мотивації студентської молоді до практик здорових моделей харчування. Висновки. Пропоновані підходи до формування внутрішніх програм моніторингу і оцінки ефективності впровадженої системи мотивації студентської молоді до практик здорових моделей харчування дасть змогу керівництву закладів вищої освіти сформувати необхідний перелік індикаторів ефективності для відслідковування дієвості впровадження заходів на усіх етапах реалізації.
Дослідження кислотності стоматологічних самопротруювальних самоадгезивних композитних цементів подвійного тверднення для фіксації та корових реставрацій
Authors: Ізай Мілан Ернестович , Мочалов Юрій Олександрович , Ступницька Олена Миколаївна , Куліш Андрій Сергійович
Published: November 2024

Вступ. Сучасні стоматологічні композитні цементи для фіксації ортопедичних конструкцій, які володіють самоадгезивними властивостями, набувають все більшої популярності. Вивчення показників кислотності (як непрямої ознаки агресивності цементу) та нейтралізації кислих компонентів в ході полімеризації є актуальним питанням у розвитку та вдосконаленні композитних цементів подвійного механізму тверднення. Методологія та методи дослідження. Мета роботи – дослідити відносний рівень кислотності компонентів у ряду самопротруювальних самоадгезивних композитних цементів подвійного тверднення для фіксації ортопедичних конструкцій та корових реставрацій зубів. Було досліджено рівень кислотності матеріалів «Breeze», «Relyx U200», «Maxcem Elite», «Totalcem», «GC-Cem-ONE, «Nova Resin Cement» та «Prolink Cem Plus». Використовували лакмусовий папір. Результати кольорової реакції сканували, аналіз рівня кислотності порівнювали у фоторедакторі «GIMP 4.0». Результати оцінювали із застосуванням тестів порівняльної статистики. Виклад основного матеріалу дослідження. Результати дослідження показали, найменші значення рН (а відповідно й вища кислотність) була у матеріалів «Breeze» (рН=2,20±0,92; М=2,50), «Maxcem Elite» (рН=2,30±0,82; М=2,50) та «RelyX U200» (рН=2,50±0,53). Середній рівень кислотності був у матеріалів «G-Cem-One» та «Nova Resin Cement», значення рН у яких були однакові – 3,20±0,42 (М=3,00). Низький рівень кислотності було встановлено у матеріалів «Prolink Cem Plus» (рН=3,80±0,79; М=4,00) і «Totalсem» (рН=5,2±0,79; М=5,00). Отримані результати дозволяють прийти до висновку щодо потенційно більш ефективного протруювання твердих тканин зубів при застосуванні матеріалів «Breeze», «Maxcem Elite» та «RelyX U200». Відповідно, у таких випадках можна очікувати на відносно вищу силу адгезії до тканин зуба при остаточній полімеризації матеріалу. Висновки. Самопротруювальні самоадгезивні стоматологічні композитні цементи подвійного тверднення для фіксації є медичними виробами, які потребують подальшого удосконалення та доопрацювання для покращення їх адгезивних властивостей, фізико-механічних характеристик та підвищення тривалості функціонування.
Stronger together? A framework for studying population resilience to climate change impacts via social shielding
Authors: Warrington Miyako , Fisher David , Komdeur Jan , Pilakouta Natalie , Griesser Michael
Published: November 2024

1. Climate change is driving a rapid increase in the frequency and intensity of extreme climatic events, leading to substantial alterations in climate patterns and other environmental conditions. These changes are often degrading habitats and increasing thermal, water, and nutritional stress for animals, thereby elevating general stress levels and imposing energetic costs. 2. Social behaviours (i.e., interactions between conspecifics) can be crucial for animals in reducing the costs imposed by these changes. Social behaviours can improve resource acquisition, reduce mortality, and provide a social buffer against physiological stress. Furthermore, helping others during reproduction can provide a buffer against reproductive failure under unfavourable environmental conditions. However, these buffering effects remain vaguely defined and it is unclear how to test for their occurrence. 3. This review explores how social behaviours can shield animals from the negative impacts of climate and environmental changes. We examine how social behaviours can provide benefits across key aspects of life, including foraging success, decreasing energetic costs, reproductive success, and the direct reduction of physiological stress. 4. We synthesize these ideas in the social shielding hypothesis and explain its key components, including the proximate mechanisms that drive social behaviours, the levels of behavioural change (individuals to groups to populations), shielding benefits across all life stages (embryo to senescence), and the ultimate consequences of these behavioural changes. 5. We emphasize that social behaviours can shield individuals under unfavourable conditions, favourable conditions, or independent of conditions, and we provide guidance on how to statistically distinguish between these different types of social shielding. These different shielding mechanisms influence how individuals and populations respond to the negative effects of climate and environmental change. 6. This framework can help predict and manage the negative effects of climate change on animals, thus guiding conservation strategies that support biodiversity and animal welfare.
PRODUCT INNOVATION SHARIA RESTRICTED INTERMEDIARY ACCOUNT IN ISLAMIC BANKING TO MACROPRUDENTIAL POLICY INSTRUMENT IN INDONESIA
Authors: Aslamah Afidah Nur , Nurzaman Mohamad Soleh
Published: November 2024

The limited availability of islamic banking products in showing their distinctive characteristics in mudharabah contracts is one of the triggers for the slow market share growth which only reached 7.3% as of December 2023. On the other hand, the Sharia Restricted Intermediary Account (SRIA) as an innovation for Islamic banks requires macroprudential policy instruments to be able to maintain financial system stability. This study aims to analyze SRIA product innovation in Islamic banking based on the Concept Note that has been prepared by the National Sharia Economic & Finance Committee on Macroprudential Policy Instruments in Indonesia in the form of Statutory Reserves (GWM), Sharia Macroprudential Intermediation Ratio (RIM), and Macroprudential Liquidity Buffer. (PLM) Syariah. The method used is Systematic Literature Review (SLR) of scientific articles in 4 quality scientific databases. There are 15 empirical articles on PSIA (Profit Sharing Investment Account) and macroprudential instruments suggesting that implementation of PSIA products requires accommodative macroprudential policy provisions. It is feared that aspects of liquidity risk and PSIA investment risk could shake the monetary stability of Islamic banking. Meanwhile, 5 other theoretical articles emphasized that PSIA is an investment product so that in essence the mudharabah contract used does not guarantee the principal value of return. The next method uses Delphi which yields results in the form of macroprudential policy t achieving the best consensus with the GWM mechanism in the range of 2% -7.5%, Sharia RIM in the range of 84-92%, and Sharia PLM 4.5% for SRIA products.
THE IMPACT OF MANAGERIAL ACCOUNTING PRACTICES ON FINANCIAL PERFORMANCE: A PRELIMINARY REVIEW
Authors: Assad Suha N. B. , Hamda Norman , Zakaria Nurazalia
Published: November 2024

Purpose: The study aims to explore the varied results from existing literature on managerial accounting practices (MAPs), identifying trends, contradictions, and research gaps. The focus is on how MAPs influence financial performance, considering both traditional and contemporary practices.
Design/methodology/approach: A comprehensive review of the literature was conducted, encompassing topics like how management accounting practices (MAPs) and strategy align, how MAPs have evolved theoretically, how firm characteristics affect MAPs, and how MAPs and organizational performance are related. 103 pertinent documents were found after searching the Scopus database for papers about "Managerial Accounting Practices and Financial Performance" from 2018 to 2024. A comma-separated file (.csv) was then prepared, including a total of 9,702 articles. VOSviewer was chosen to help with this analysis.
Findings: The study reveals a lack of consensus regarding the relationship between MAPs and firm performance. Some studies show a positive correlation, while others report limited or even negative impacts. These findings highlight the complexities and nuances of the relationship between MAPs and firm performance.
Research limitations/implications: The study emphasizes the need for more nuanced theoretical frameworks, standardized measurement tools, and research in developing countries to better understand the impact of MAPs on organizational performance.
Practical implications: The study's findings underscore the importance of considering contextual factors and adopting tailored MAP strategies to maximize organizational success. This has significant implications for organizational managers, policymakers, and researchers.
Originality/value: This study contributes to the literature by offering a comprehensive synthesis of existing research on MAPs, highlighting the complexities in their relationship with firm performance, and providing valuable insights for future research and practical application.
MERGING ETHICS AND INNOVATION: MEETING SOCIETY 5.0 HALAL COSMETICS NEEDS BY HARNESSING IR5.0
Authors: Masood Adlin
Published: November 2024

The Islamic Monetary Economy (IME), which has a value over $3 trillion USD, is currently seeing a shift towards finance that is both ethical and sustainable. This shift aligns with the fundamental concepts of Maqasid Shariah, which are the higher purposes of Islamic law. This collaboration offers a distinct advantage for the growing Halal cosmetics industry. Consumer demand goes beyond religious adherence and includes ethical sourcing and environmental factors, which aligns well with Maqasid Shariah's focus on well-being and social responsibility (Hifz an-Nasl and Hifz al-Mal). Halal cosmetics brands adhere to Halal standards and embrace Society 5.0 ideals. They not only fulfil religious requirements but also contribute to the IME's ethical and sustainable mission. In addition, the convergence is facilitated by Industry 5.0 (IR5.0) technologies such as Artificial Intelligence (AI) and Augmented Reality (AR). Artificial intelligence (AI) customises marketing efforts, guaranteeing that ethical messages strongly connect with consumers. Augmented reality (AR) promotes transparency by enabling consumers to digitally investigate the sources of products and the processes involved in their manufacture. The combination of technology and ethical business practices not only promotes growth within the IME, but also supports a fair and environmentally friendly future, establishing the importance of Halal cosmetics in a Society 5.0 that aligns with Maqasid Shariah.
THE LIFE CYCLE THEORY AND PERMANENT INCOME THEORY IN HOUSEHOLD FINANCIAL SUSTAINABILITY
Authors: Ab Wahab Siti Nur Aqilah , Japang Minah , Hock Ann Lee , Azman Nur Shahirah
Published: November 2024

This article explains the interplay between the Life Cycle Theory (LCT) and Permanent Income Theory (PIT) in the domain of household financial sustainability. By integrating these two prominent frameworks, it offers a comprehensive approach to understanding how households manage their financial activities across their lifetimes. Considering the criticisms of both consumption theories, the article aims to provide valuable insights into distinct aspects of household personal sustainable finance, particularly in the areas of debt management and repayment, assessing sustainable consumption behavior, household expenditure and investment patterns, as well as the utilization and reduction of debt. Integrating these two theories presents a more holistic understanding of household financial sustainability.
BOARD DIVERSITY AGAINST FIRM VALUE IN CORPORATE GOVERNANCE PERSPECTIVE
Authors: Syahputri Alvina Dwi , Biduri Sarwenda , Hariyanto Wiwit , Noor Abidin Fityan Izza , Utomo Prasetyo
Published: November 2024

Research Purposes: The study aims to find out the impact of board diversity on the firm value from the perspective of corporate governance for food and beverage industry manufacturing companies listed on the Indonesia Stock Exchange in 2016–2022.
Methods: Sampling in this study used the purposive sampling method taken from the annual reports of companies in the food and beverage manufacturing sector for 2016–2022.
Finding: It was found that the term and nationality of the board of directors has an effect on  firm value. While gender diversity, age and educational background of the board of directors has no effect on firm value.
Novelty: In this study the authors focus on board diversity with complete indicators. Previous research only uses gender, nationality, and education as free variables. In this study, authors add two free variables that is tenure and age. And unlike previous studies that used chemical sector companies as research objects, this study used food and beverage industry manufacturing companies as the research object.
CONSUMER-CENTRIC MARKETING STRATEGY: HOW PRODUCT REVIEWS, BRAND IMAGE, AND BRAND AWARENESS ARE TRANSFORMING THE GAME IN THE BEAUTY INDUSTRY OF SURABAYA RAYA, INDONESIA.
Authors: Febriansah Rizky Eka , Prapanca Detak , Prasojo Bayu Hari
Published: November 2024

One of the increasingly influential sources of information is online reviews, which are provided by consumers who have used a product or service. On the other hand, brand image and consumer perception of a brand's characteristics, quality, and value play a crucial role in shaping their perception of a product. This study aims to bridge this knowledge gap by identifying and analyzing how online reviews and brand image influence purchasing decisions for local beauty products. The focus is on how customer satisfaction acts as a bridge between the two factors.The researcher utilized primary data through a quantitative approach, focusing on users of local beauty products such as Wardah, Emina, Purbasari, etc. in the Greater Surabaya Area, East Java Province. Purposive sampling was employed as the sampling technique in this study. Hypothesis testing was conducted using the Partial Least Square (PLS) method through the SmartPLS 4 application.Based on the results of the direct influence hypothesis testing, it can be concluded that online customer reviews have a positive and significant effect on purchasing decisions. Brand image also has a positive and significant effect on purchasing decisions. However, brand awareness has a positive but insignificant effect on purchasing decisions. Additionally, online customer reviews have a positive and significant effect on brand awareness, while brand image has a negative and insignificant effect on brand awareness. Brand awareness can mediate the effect of online customer reviews on purchasing decisions, as well as the effect of brand image on purchases.
A STUDY ON AWARENESS AND UNDERSTANDING OF TAKAFUL PRODUCTS AMONG POLYTECHNIC STUDENTS IN MALAYSIA
Authors: Abdul Rahman Aziah , Samsudin Khairul Jannah , Osman Noradilla
Published: November 2024

The study aims to assess the awareness and understanding of Takaful among polytechnic students in Malaysia, focusing on demographic influences and perceptions.Utilizing a quantitative approach, the research employed a cross-sectional survey design. A structured questionnaire was distributed to 95 students from four polytechnics, collecting data on demographics, awareness, understanding, and perceptions of Takaful products.The results revealed a moderate to high level of awareness, particularly among students aged 20-21. A significant understanding of Takaful's alignment with Islamic principles was noted, but gaps remained in comprehending specific benefits and complexities. Younger students (ages 18-19) demonstrated lower awareness and understanding.The findings underscore the need for targeted educational interventions to enhance Takaful awareness, especially among younger students. Integrating Takaful concepts into academic curricula and leveraging social media for outreach can foster greater participation in Islamic financial products. Overall, this research contributes valuable insights for Takaful operators and policymakers, aiding in the development of effective marketing strategies and educational programs.
THE ROLE OF ARTIFICIAL INTELLIGENCE (AI) AND PRODUCT POPULARITY IN SHAPING CONSUMER BUYING BEHAVIOR ON INDONESIAN E-COMMERCE PLATFORMS
Authors: Pebrianggara Alshaf , Yulianto Muhammad Rizal , Himawan Al Akbar
Published: November 2024

This study aims to bridge the gap in the literature by examining how artificial intelligence (AI) and product popularity play a role in shaping consumer purchasing behavior on Indonesian e-commerce platforms. The sample is users who make purchases of cosmetic products with AI features on Indonesian E-Commerce. Using multiple linear regression methods and SPSS 25 as a calculation tool. It was found that artificial intelligence and product popularity have a significant influence on consumer purchasing behavior in Indonesian E-Commerce.
TAX PLANNING, INFORMATION ASYMMETRY AND FREE CASH FLOW TO EARNINGS MANAGEMENT WITH GOOD CORPORATE GOVERNANCE AS A MODERATING VARIABLE
Authors: Eri Anggraeni  , Eny Maryanti  , Cicik Suciati  , Nihlatul Qudus Sukma Nirwana
Published: November 2024

This research was conducted with the aim of examining the effect of tax planning, information asymmetry and free cash flow on earnings management, as well as good corporate governance as a moderator of the relationship between tax planning, information asymmetry and free cash flow on earnings management. The data used is in the form of annual reports of companies in the goods & consumer industry  sector listed on the Indonesia Stock Exchange (IDX) for the 2018-2021 period. The method used is quantitative with an analytical tool in the form of multiple linear regression. The results show that tax planning and information asymmetry have an effect on earnings management, while free cash flow has no effect on earnings management. Good corporate governance is able to moderate the relationship between tax planning, information asymmetry and free cash flow on earnings management. The implications of this research are expected to make a positive contribution to investors and creditors to be more careful in assessing management performance, company conditions and understanding reported earnings, because these profits are not necessarily true profits. This research is expected to provide input for companies to observe earnings management activities carried out by management for the benefit of management itself.
A CRITICAL REVIEW OF TAX AUDIT QUALITY FACTORS: A RESEARCH SYNTHESIS
Authors: Taib Nor Asiah , Muhammad Izlawanie , Abdul Hamid Suhaila
Published: November 2024

The quality of tax audits plays a critical role in ensuring the transparency, accuracy, and integrity of the taxation system, which in turn contributes to public confidence and higher tax compliance. In an increasingly complex and dynamic business world, understanding the factors that affect the quality of tax audits is becoming increasingly important. Therefore, this study aims to systematically review the existing literature to identify and analyze the factors. The motivation of this study is to fill the knowledge gap and provide a comprehensive guide for researchers and practitioners in the field of taxation. Data sources are obtained from academic journals by identifying the main themes and patterns that encompass from around the world, countries in Southeast Asia, and narrow down to Malaysian studies. The categorization of tax audit quality studies into these three groups allows for the identification of variations in the variables and research techniques used, as well as the comprehension of the cultural and regional context for the audit quality study issue. The results of the study show that there are several main factors that affect the quality of tax audits, including auditor skills, knowledge, experience, information technology (IT), job satisfaction and time. The study also found that the interaction between these factors can strengthen or weaken the quality of tax audits. In conclusion, this study provides an in-depth view of the factors that affect the quality of tax audits and underlines the importance of a holistic approach in dealing with this issue. The findings of this study can help tax authorities, audit firms, and policy makers especially to Inland Revenue Board of Malaysia (IRBM) in devising more effective strategies to improve the quality of tax audits.
EXAMINING THE INFLUENCE OF PRODUCT QUALITY, SERVICE QUALITY, AND DELIVERY PERFORMANCE ON GENERATION Y’S ONLINE SHOPPING SATISFACTION: THE MEDIATING ROLE OF PERCEIVED SECURITY
Authors: Mursidi Amalina , Mahyudin Wan A’tirah , Mohd Soffian Lee Umi Hamidaton
Published: November 2024

This study investigates the impact of various factors on customer satisfaction in online shopping among Generation Y, focusing on product quality, service quality, and shipping performance as independent variables. Additionally, it explores the mediating role of security in this relationship. The research aims to understand how these elements contribute to the overall satisfaction of Generation Y consumers in the digital marketplace. A comprehensive survey was conducted among Generation Y online shoppers, analyzing their perceptions and experiences. The findings indicate service quality significantly influence customer satisfaction. However, the perceived security of online transactions mediates these relationships, enhancing the overall satisfaction when consumers feel secure. The study highlights the critical role of security in online shopping, suggesting that e-commerce platforms must prioritize secure transactions to boost customer satisfaction among Generation Y. These insights offer valuable implications for online retailers seeking to enhance the shopping experience for this tech-savvy and influential demographic.
THE EFFECT OF FAIR VALUE ACCOUNTING ON EARNINGS QUALITY IN JORDANIAN BANKING AND REAL ESTATE SECTORS: CONCEPTUAL PERSPECTIVE
Authors: Mubaideen Ahmed Mohammad , Laili Nur Hidayah , Jamil Nurul Nazlia , Khairi Khairil Faizal
Published: November 2024

This study aims to explore the concept of Fair Value Accounting (FVA) and its effects on Earnings Quality (EQ) measures within the banking and real estate sectors listed on the Amman Stock Exchange (ASE). The significance of the study is derived from the importance of FVA, as the quality of accounting earnings is a crucial component in measuring the quality of financial reports based on FVA. EQ represents the ability to predict future earnings and the stability of bank earnings through EQ measurements. The introduction of International Financial Reporting Standards (IFRS) has mandated compliance for all listed companies in the banking and real estate sectors in Jordan, presenting a significant challenge for accountants. This challenge arises because the standards emphasize the importance of fair value (FV) on listings at the Amman Stock Exchange, aiming to enhance the genuine and fair representation of financial reports. IFRS has introduced FVA to these companies to evaluate their earnings from assets and liabilities in Jordan, following IFRS recommendations. EQ measures are based on four attributes: persistence, predictability, volatility of earnings, and closeness to cash, as reflected in the companies' income statements. This study anticipates that strict compliance with IFRS standards will significantly improve EQ through enhancements in these measures. Based on the available literature, this conceptual study posits that FVA impacts EQ measures such as persistence, predictability, volatility of earnings, and closeness to cash in the Jordanian banking and real estate sectors. It concludes that poor implementation of FVA adversely affects EQ measurements in these sectors in Jordan.
Effect of 6 GHz Radiofrequency Electromagnetic Field on Cytokine Levels in Rats
Authors:   Çukurova University Faculty of Medicine Department of Biophysics, Turkey, Karamazı Yasin , Emre Mustafa ,   Çukurova University Faculty of Medicine Department of Biophysics, Turkey, Emre Toygar ,   Boğaziçi University Faculty of Engineering Department of Industry, Turkey, Çetiner Salih ,   Çukurova University Balcali Hospital Central Laboratory, Turkey, Aksoy Gülsevinç ,   Çukurova University, Faculty of Medicine, Department of Medical Biology, Turkey, Aydın Çağatay ,   Ege University, Faculty of Engineering, Department of Electrical-Electronics, Turkey
Published: November 2024

Purpose: While technological devices are continuously developing at an incredible speed, the exposure to radiofrequency
electromagnetic fields (RF-EMF) created by these devices is gradually increasing. In this study investigated the effects of 6
GHz (0.083 W/kg SAR) RF-EMF on rat cytokine levels.
Materials and Methods: In this study, 20 Wistar Albino adult male rats ranging in weight between 250-300 g were used.
Rats were divided into two groups as; Control and radiofrequency radiation (RFR) group. The control were not subjected to
any treatment. RFR group rats were placed in a special treatment cage and exposed to 6 GHz RF-EMF for 4 hours/day for 6
weeks. After RF-EMF application, blood (2cc) were collected from all rats by cardiac puncture method. The plasmas of the
collected blood were separated from the blood samples within the same day. Pro-inflammatory cytokine (TNF-α, IFN-γ) and
anti-inflammatory cytokine (IL-4, IL-10) levels were analyzed as spectrophotometrically by ELISA method.
Results: We found a statistically significant increase in plasma levels of TNF-α and IL-4 rats in the RFR group compared
to the control (p<0.05). We also found an increase in the plasma level IFN-γ and IL-10, but they have no statistically
significance (p>0.05).
Conclusion: 6 GHz RF-EMF exposure had significant effects on rat cytokine levels. It supported both pro-inflammatory and
anti-inflammatory cytokine release.
Dexamethasone is associated with reduced frequency and intensity of cytokine release syndrome compared with alternative corticosteroid regimens as premedication for glofitamab in patients with relapsed / refractory large B-cell lymphoma
Authors: Falchi Lorenzo , Hutchings Martin , Carlo-Stella Carmelo , Morschhauser Franck , Dickinson Michael , Cartron Guillaume , Khan Cyrus , Tani Monica , Martinez-Lopez Joaquin , Bartlett Nancy L. , Salar Antonio , Brody Joshua D. , Leppä Sirpa , Berthier Aurelien , Kallemeijn Martine , Relf James , Tchaleu Fabiola Bene , Lundberg Linda , Bachy. Emmanuel
Published: November 2024

Not available.
Isatuximab, pomalidomide, and dexamethasone as salvage therapy for patients with multiple myeloma: the Italian, multicenter, retrospective clinical experience with 270 cases outside of controlled clinical trials
Authors: Martino Enrica Antonia , Derudas Daniele , Rossi Elena , Terlizzi Sofia , Reddiconto Giovanni , Stefanoni Paola , Micozzi Jacopo , Mangiacavalli Silvia , Zamagni Elena , Offidani Massimo , Furlan Anna , Buda Gabriele , Lotti Flavia , Liberatore Carmine , Lazzaro Antonio , Pepa Roberta Della , Bertuglia Giuseppe , Barbieri Emiliano , Conticello Concetta , De Magistris Claudio , De Paoli Lorenzo , Bongarzoni Velia , Cafro Anna Maria , Mele Anna , Benvenuti Pietro , Cerchione Claudio , Botta Cirino , Antonioli Elisabetta , Sgherza Nicola , Aquino Sara , Mele Giuseppe , Barilà Gregorio , Palmieri Salvatore , Annibali Ombretta , Bianco Rosario , Febbo Massimiliano Arangio , Casaluci Gloria Margiotta , Rago Angela , Fontana Raffaele , Farina Francesca , Vigna Ernesto , Bruzzese Antonella , Mancuso Katia , Nappi Davide , Morè Sonia , Rivolti Elena , Califano Catello , Amendola Angela , Roccotelli Daniela , Lombardo Alessandra , Citro Annalisa , Uccello Giuseppina , Zambello Renato , Maggi Alessandro , Neri Santo , Monachesi Michele , Gozzetti Alessandro , Montefusco Vittorio , Brunori Marino , Cotzia Emilia , Pietrantuono Giuseppe , Quinto Angela Maria , Amico Valeria , Di Renzo Nicola , Coscia Marta , Galli Monica , De Stefano Valerio , Petrucci Maria Teresa , Neri Antonino , Di Raimondo Francesco , Morabito Fortunato , Musto Pellegrino , Gentile Massimo
Published: November 2024

Not available.
Clinical characteristics of toxoplasmosis patients in Korea: A retrospective study using health insurance review and assessment service data and electronic medical records
Authors: Ham Do-Won , Jung Bong-Kwang , Shin Ji-Hun , Kim Yong Joon , Seo Kyoung Yul , Lee Seung Mi , Im Jae Hyoung , Kwon Jeong-Ran , Lee Ho-Sung , Hwang Kyung-Won , Shin Eun-Hee
Published: November 2024

This study aimed to elucidate the clinical characteristics of patients diagnosed with toxoplasmosis in Korea. We collected and analyzed the specific research data of 5,917 patients from the Health Insurance Review and Assessment (HIRA; 2007–2020) and 533 electronic medical records (EMRs; 2003–2021) of Korean patients. The HIRA data showed that toxoplasmosis is an endemic disease that occurs constantly in Korea, with a large proportion of patients complaining of ocular symptoms. Of the 533 patients for whom EMR data were available, 54.6% were diagnosed with toxoplasmosis; ocular toxoplasmosis (35.7%), congenital toxoplasmosis (4.7%), cerebral toxoplasmosis (4.1%), pulmonary toxoplasmosis (0.4%), and toxoplasma hepatitis (0.6%), in order of frequency. In ocular cases, 54.4% of the patients had diverse ocular pathologies. Toxoplasmosis in Korea is characterized by a high frequency of ocular symptoms, most patients are adults, and 51.8% of patients with seropositivity were positive for IgG, suggesting prior infection. This study highlights that patients with ocular symptoms are included in the major diagnosis group for acquired toxoplasmosis in Korea.
Current status of intestinal parasite infections in fecal samples of dogs in Korea
Authors: Lee You-Jeong , Kim Beoul , Kwak Dongmi , Seo Min-Goo
Published: November 2024

This study surveyed the current status of intestinal parasite infections in Korean dog fecal samples. A total of 367 fecal samples were collected from the northern (Seoul and Gyeonggi-do), central (Chungcheong-do), and southern (Gyeongsang-do) regions and analyzed using the saturated sodium nitrate flotation technique and the nucleotide sequences of 18S rRNA. Six species of intestinal parasites were detected using the flotation technique. Among them, helminth eggs detected included Toxocara canis (6.0%), Toxascaris leonina (1.1%), Trichuris vulpis (6.8%), Ancylostoma caninum (2.7%), and Spirometra sp. (1.1%). Additionally, Cystoisospora sp. (7.6%) oocysts were also detected. The prevalence of intestinal parasite infections was higher in shelter dogs than in pet dogs. Molecular genetic assays revealed the gdh and 18S rRNA genes of Giardia duodenalis (type D) in 4.9% of fecal samples. To the best of our knowledge, 18S rRNA genes of Cryptosporidium canis were identified in 1.9% of fecal samples for the first time in Korea. These findings provide an overview of the current status of intestinal parasite infections in fecal samples of dogs from Korea and can be helpful in the surveillance of zoonotic parasite infections related to dogs.
Infection status and species diversity of trematode cercariae in freshwater snails from canal networks in the Bangkok Metropolitan Region, Thailand
Authors: Rachprakhon Phuphitchan , Purivirojkul Watchariya
Published: November 2024

This study aimed to investigate the infection status and species diversity of trematode cercariae in freshwater snails from canal networks in the Bangkok Metropolitan Region (BMR), Thailand. The snails were collected from 35 sites during 2 cycles of the wet (July–October) and dry (November–June) seasons in 2018–2019. A total of 29,420 snails representing 24 species/subspecies were examined for cercarial infection using shedding and crushing techniques. We found that 1,275 snails from 12 species/subspecies were infected, resulting in an overall prevalence of 4.3%. Infections were significantly higher (p<0.001) during the wet season (5.9%; 970/16,473) than during the dry season (2.4%; 305/12,947). Morphological identification revealed 37 distinct types within 15 morphotypes, with the armatae morphotype showing the highest infection rate (1.8%) and the greatest cercarial diversity (8 distinct types). This study highlights the health risk posed by the Bithynia siamensis siamensis, which was the second most prevalent (8.5%) and hosted the greatest cercarial diversity (11 morphotypes, 15 distinct types). This subspecies also displayed a wide distribution range (31 localities) with a generally high occurrence frequency in the BMR. This study firstly documents a gymnophallid digenean as a freshwater digenean, presenting evidence of a dichotoma cercarial morphotype from 4 species/subspecies (Filopaludina martensi martensi, F. sumatrensis polygramma, B. siamensis siamensis, and Wattebledia siamensis) with a low infection range (0.1–0.4%). A staggering diversity of cercariae was observed in the BMR canal networks with seasonal fluctuations. The B. siamensis siamensis displayed notable epidemiological importance in the BMR flowing-water networks. This study provides quantitative and qualitative morphological descriptions and measurement guidelines for the dichotoma cercaria in Thailand.
Microscopic findings of host–parasite interaction between the Korean rockfish, Sebastes schlegelii, and the monogenean ectoparasite, Microcotyle sebastis
Authors: Shin Sang Phil , Kim Seokryel
Published: November 2024

This study was conducted to examine the pathogenesis of gill degeneration in the Korean rockfish Sebastes schlegelii, infested with the monogenean ectoparasite, Microcotyle sebastis. We collected 30 Korean rockfish from a fish farm in Tongyeong-si, Gyeongsangnam-do, and examined them with light microscopy, scanning electron microscopy (SEM), and histopathology, in March 2018. The monogenean trematode, M. sebastis, was detected in 27 Korean rockfish (90%), with the intensity of infection being 31.7 per fish. The characteristic surface ultrastructures such as tegument with transverse striations, genital atrium, genital pore, and opisthaptor with numerous clamps were observed. The worms were firmly attached to the gill lamellae using clamps from the opisthaptor, causing gill damage and degeneration. The distal part of the lamellae was ruptured by the sclerites of the clamps. The histopathological examination revealed epithelial hypertrophy, hyperplasia, and occasionally fusion of the lamellae. These ultrastructural and histopathological findings provide some understanding of the pathogenesis of gill degeneration in the Korean rockfish infested with M. sebastis.
GOOD AGEING
Authors:   , Greubel Carla Sophia
Published: November 2024

In times of demographic change and crumbling health and care systems, governments, industry and public health care providers in Europe increasingly turn to digital health and social care innovations for providing care to older people. However, the digitalisation of ageing and care is not a neutral endeavour. Digital innovations often problematise elements in the lives of older people that are not evident, agreed-upon problems. At the same time, they also specify normative notions of ‘good ageing’, for example by promising to facilitate active or healthy lifestyles.

The notions of good ageing that digital innovations introduce into the everyday lives of older people interfere with various other and sometimes conflicting forms of good ageing that the older adults also care about. In this dissertation I have studied such conflicts or frictions between different ways in which ‘good ageing’ is envisioned and done in four different digital innovation initiatives for older people in Europe: the development of a EU policy vision on the digitalisation of ageing and care; a Barcelona digital public service for the prevention and mitigation of loneliness; and two pilot studies in Italy and the UK, where one involved a public-private partnerships with a big tech company while the other followed a more bottom-up community based approach. These four digital innovation initiatives vary significantly in their aims, approaches, actors and (power) relations, and I consider how this influences what kinds of frictions arise and how frictions are accommodated.

Drawing on literature from Science and Technology Studies, Ageing Studies, and Socio-gerontechnology, I analyse instances of frictions to answer the question: how do, in the context of an ongoing digitalisation of ageing and care, some forms of ‘good ageing’ come to matter more and how are others rendered invisible or marginalised? In this dissertation I argue that, if digital innovations are to facilitate forms of good ageing that older people themselves actually care about, and thus, if they are to be used on a wider scale, it is time to take frictions between different forms of good ageing more seriously than current digital innovation initiatives tend to do.
Battling Pediatric Mold Infections: Invasive Aspergillosis and Invasive Mucormycosis
Authors: Roberts Eleanor
Published: November 2024

Mold species are inhaled by people every day and, typically, infection is locally curtailed by the immune system. However, in people who are immunocompromised, invasive aspergillosis (IA) or invasive mucormycosis (IM) can lead to great morbidity and even mortality. Although many studies have been conducted in adults regarding diagnosis and treatment of IA and IM, infections in children have been investigated to a much lower extent. Surabhi Vora is a pediatrician based in Seattle who specializes in treating immunocompromised children with fungal infections. Here, she discusses several issues around IA and IM in these populations, including the importance of detecting and treating these infections early. Diagnosis of IA and IM may be problematic in children as symptoms can be non-specific, such as repeated bouts of fever; chest CTs and laboratory tests may not be as accurate as needed; and accessing tissue for biopsy can be difficult. Treatment of IA and IM can depend on a number of factors, such as the specific pathogen, drug–drug interactions, and a child’s age and ability to consume a medication. Education is needed for both patients and caregivers, especially with regard to the need to take medication for extended periods of time and be on guard for both further IA or IM symptoms and for medication side effects.
PARADOXES OF GRAVITY: Newton's Law Does Not Work at Large Distances, but... it's too early to throw it in the scrapheap. It's still needed.
Authors: Kosinov Mykola
Published: November 2024

The dominant force in the Universe is gravity. For over 300 years, the gravitational force was represented by a single simple and mathematically perfect formula - Newton's law of gravity FN = GmM/r^2. However, the boundaries of its applicability are limited to the solar system. The revealed gravitational anomalies in the dynamics of stars show that at large distances, Newton's law is not satisfied and has significant discrepancies with observations. The real law of gravity is more complex than Newton's law. For large distances and large masses, the gravitational force dominates in the Universe, which Newton's law "does not see". A new law of gravity Fcos = (mc^2)√Ʌ was obtained, which shows the cosmological force not taken into account by Newton's law. Two laws of gravity (Newton's law + the law of cosmological force) provide a complete description of the gravitational interaction in the Universe.
Case Report: Acute myocarditis and cerebral infarction following Bothrops lanceolatus envenomation in Martinique: a case series
Authors: Florentin Jonathan , Farid Karim , Kallel Hatem , Neviere Remi , Resiere Dabor
Published: November 2024

Bothrops lanceolatus (Bl), a snake endemic to Martinique, is responsible for numerous envenomations annually, leading to severe complications such as thrombosis, necrosis, and hemorrhage. This case series investigates the link between Bothrops lanceolatus envenomation and acute myocarditis, utilizing cardiac magnetic resonance imaging (MRI) to enhance management strategies. In both cases, cardiac MRI confirmed myocarditis with edema, and subsequent cerebral MRI revealed bilateral infarcts. Elevated troponin levels further supported the myocarditis diagnosis. Multiple doses of Bothrofav® antivenom facilitated recovery without clinical after effects.These cases represent the first documented instances of myocarditis due to Bl envenomation confirmed via cardiac MRI. Prompt administration of antivenom and the use of advanced imaging techniques were crucial in achieving favorable outcomes.