bluuebunny/crossref_metadata_2025 huggingface dataset:
Textures of Black sound and affect: Life and death in New Orleans
Authors: Sakakeeny Matt
Published: March 2024

Abstract

In a traditional New Orleans jazz funeral, the characteristic shift from mourning to joy is propelled by brass band musicians weaving melodies and rhythms together. This article is about how these thickly layered textures of sound elicit shared sentiments of lament and of joy. More than an accumulation of individual layers, the textures and emotions compose an atmosphere, in both the physical and metaphorical sense, of mutual aid. The relative openness of the sound—the fact that it cannot be reduced to its communicative content—means that it can also be heard as a political act of refusal, rebellion, or something else altogether. An underrecognized keyword in sound studies, texture is placed here in a web of relations with other keywords: affect, assembly, atmosphere, care, fugitivity, joy/lament, life/death, mutual aid, rebellion, refusal, religiosity, voice/instrument. Textures of sound do not explicitly call for an end to anti‐Black violence, and I am hesitant to even characterize the jazz funeral as an act of resistance. But I suggest that the assemblies of Black sounds and bodies “speak” to the possibility of liberation and generate an atmosphere of mutual aid.
Autoimmune cytopenia and Kabuki syndrome in paediatrics: Insights in 11 patients
Authors: Bianchi Chloé , Margot Henri , Fernandes Helder , Pasquet Marlène , Priqueler Laurence , Roy‐Peaud Frédérique , Bauduer Frédéric , Bayart Sophie , Garnier Nathalie , Fain Olivier , Van Gils Julien , Joly Sandrine Baron , Rialland Fanny , Paillard Catherine , Deparis Marianna , Lambilliotte Anne , Leblanc Thierry , Fahd Mony , Leverger Guy , Héritier Sébastien , Geneviève David , Rieux‐Laucat Frédéric , Picard Capucine , Neyraud Caroline , Aladjidi Nathalie
Published: March 2024

Kabuki syndrome (KS) is now listed in the Human Inborn Errors of Immunity (IEI) Classification. It is a rare disease caused by KMT2D and KDM6A variants, dominated by intellectual disability and characteristic facial features. Recurrently, pathogenic variants are identified in those genes in patients examined for autoimmune cytopenia (AIC), but interpretation remains challenging. This study aims to describe the genetic diagnosis and the clinical management of patients with paediatric‐onset AIC and KS. Among 11 patients with AIC and KS, all had chronic immune thrombocytopenic purpura, and seven had Evans syndrome. All had other associated immunopathological manifestations, mainly symptomatic hypogammaglobinaemia. They had a median of 8 (5–10) KS‐associated manifestations. Pathogenic variants were detected in KMT2D gene without clustering, during the immunological work‐up of AIC in three cases, and the clinical strategy to validate them is emphasized. Eight patients received second‐line treatments, mainly rituximab and mycophenolate mofetil. With a median follow‐up of 17 (2–31) years, 8/10 alive patients still needed treatment for AIC. First‐line paediatricians should be able to recognize and confirm KS in children with ITP or multiple AIC, to provide early appropriate clinical management and specific long‐term follow‐up. The epigenetic immune dysregulation in KS opens exciting new perspectives.
Faster clinical decisions in B‐cell acute lymphoblastic leukaemia: A single flow cytometric 12‐colour tube improves diagnosis and minimal residual disease follow‐up
Authors: Lebecque Benjamin , Besombes Joevin , Dannus Louis‐Thomas , De Antonio Marie , Cacheux Victoria , Grèze Victoria , Montagnon Valentin , Veronese Lauren , Tchirkov Andrei , Tournilhac Olivier , Berger Marc G. , Veyrat‐Masson Richard
Published: March 2024

Assessing minimal residual disease (MRD) in B‐cell precursor acute lymphoblastic leukaemia (BCP‐ALL) is essential for adjusting therapeutic strategies and predicting relapse. Quantitative polymerase chain reaction (qPCR) is the gold standard for MRD. Alternatively, flow cytometry is a quicker and cost‐effective method that typically uses leukaemia‐associated immunophenotype (LAIP) or different‐from‐normal (DFN) approaches for MRD assessment. This study describes an optimized 12‐colour flow cytometry antibody panel designed for BCP‐ALL diagnosis and MRD monitoring in a single tube. This method robustly differentiated hematogones and BCP‐ALL cells using two specific markers: CD43 and CD81. These and other markers (e.g. CD73, CD66c and CD49f) enhanced the specificity of BCP‐ALL cell detection. This innovative approach, based on a dual DFN/LAIP strategy with a principal component analysis method, can be used for all patients and enables MRD analysis even in the absence of a diagnostic sample. The robustness of our method for MRD monitoring was confirmed by the strong correlation (r = 0.87) with the qPCR results. Moreover, it simplifies and accelerates the preanalytical process through the use of a stain/lysis/wash method within a single tube (<2 h). Our flow cytometry‐based methodology improves the BCP‐ALL diagnosis efficiency and MRD management, offering a complementary method with considerable benefits for clinical laboratories.
Schwere atopische Dermatitis im frühen Kindesalter: Besonderheiten, Herausforderungen und neue Perspektiven in der Versorgung
Authors: Weins Andreas Benedikt , Kerzel Sebastian , Schnopp Christina
Published: March 2024

Die atopische Dermatitis ist die häufigste chronische Hauterkrankung im Kindesalter mit einer Prävalenz von 10% bei Kleinkindern unter 2 Jahren, wovon etwa 15% einen hohen Schweregrad aufweisen. „Kinder sind keine kleinen Erwachsenen“, dies trifft für die schwere frühkindliche atopische Dermatitis in besonderem Maße zu. Innerhalb dieser sensiblen Lebensphase zeigen sich alterstypische Facetten der Erkrankung (psychosozial, neurokognitiv, klinisch‐morphologisch), die Unterschiede im Management mit sich bringen.

Besondere Bedeutung hat die Identifikation von Säuglingen und Kleinkindern mit früh‐persistierendem, schwerem Verlauf mit Blick auf eine erstmals für diese Altersgruppe zugelassene Systemtherapie: sowohl für die unmittelbare Versorgung der Hauterkrankung als auch unter dem Aspekt einer möglichen Prävention von Begleiterkrankungen. Da der „atopische Phänotyp“ klinische Überlappungen zum Spektrum der Immundefekte aufweist, ist die korrekte Einordnung des Hautbefundes bei therapierefraktärem Ekzem essenziell. In dieser Arbeit beschreiben wir eine alltagstaugliche Strategie, um anhand anamnestischer Warnhinweise, dermatologischer Leitbefunde und Labordiagnostik eine Abgrenzung von ekzematösen Hauterscheinungen bei primären Immundefekten vorzunehmen. Dazu geben wir aktuelle Empfehlungen zum Management des schweren frühkindlichen atopischen Ekzems, auch in Bezug auf die Indikation zur Systemtherapie.
A synthetic flavonoid derivate in the plasma membrane transforms the voltage‐clamp fluorometry signal of CiHv1
Authors: Pethő Zoltán , Pajtás Dávid , Piga Martina , Magyar Zsuzsanna , Zakany Florina , Kovacs Tamas , Zidar Nace , Panyi Gyorgy , Varga Zoltan , Papp Ferenc
Published: March 2024

Voltage‐clamp fluorometry (VCF) enables the study of voltage‐sensitive proteins through fluorescent labeling accompanied by ionic current measurements for voltage‐gated ion channels. The heterogeneity of the fluorescent signal represents a significant challenge in VCF. The VCF signal depends on where the cysteine mutation is incorporated, making it difficult to compare data among different mutations and different studies and standardize their interpretation. We have recently shown that the VCF signal originates from quenching amino acids in the vicinity of the attached fluorophores, together with the effect of the lipid microenvironment. Based on these, we performed experiments to test the hypothesis that the VCF signal could be altered by amphiphilic quenching molecules in the cell membrane. Here we show that a phenylalanine‐conjugated flavonoid (4‐oxo‐2‐phenyl‐4H‐chromene‐7‐yl)‐phenylalanine, (later Oxophench) has potent effects on the VCF signals of the Ciona intestinalis HV1 (CiHv1) proton channel. Using spectrofluorimetry, we showed that Oxophench quenches TAMRA (5(6)‐carboxytetramethylrhodamine‐(methane thiosulfonate)) fluorescence. Moreover, Oxophench reduces the baseline fluorescence in oocytes and incorporates into the cell membrane while reducing the membrane fluidity of HEK293 cells. Our model calculations confirmed that Oxophench, a potent membrane‐bound quencher, modifies the VCF signal during conformational changes. These results support our previously published model of VCF signal generation and point out that a change in the VCF signal may not necessarily indicate an altered conformational transition of the investigated protein.
Translation initiation factor eIF1A rescues hygromycin B sensitivity caused by deleting the carboxy‐terminal tail in the GPN‐loop GTPase Npa3
Authors: Félix‐Pérez Tania , Mora‐García Martín , Rebolloso‐Gómez Yolanda , DelaGarza‐Varela Alda , Castro‐Velázquez Grecia , Peña‐Gómez Sonia G. , Riego‐Ruiz Lina , Sánchez‐Olea Roberto , Calera Mónica R.
Published: March 2024

The essential yeast protein GPN‐loop GTPase 1 (Npa3) plays a critical role in RNA polymerase II (RNAPII) assembly and subsequent nuclear import. We previously identified a synthetic lethal interaction between a mutant lacking the carboxy‐terminal 106‐amino acid tail of Npa3 (npa3ΔC) and a bud27Δ mutant. As the prefoldin‐like Bud27 protein participates in ribosome biogenesis and translation, we hypothesized that Npa3 may also regulate these biological processes. We investigated this proposal by using Saccharomyces cerevisiae strains episomally expressing either wild‐type Npa3 or hypomorphic mutants (Npa3ΔC, Npa3K16R, and Npa3G70A). The Npa3ΔC mutant fully supports RNAPII nuclear localization and activity. However, the Npa3K16R and Npa3G70A mutants only partially mediate RNAPII nuclear targeting and exhibit a higher reduction in Npa3 function. Cell proliferation in these strains displayed an increased sensitivity to protein synthesis inhibitors hygromycin B and geneticin/G418 (npa3G70A > npa3K16R > npa3ΔC > NPA3 cells) but not to transcriptional elongation inhibitors 6‐azauracil, mycophenolic acid or 1,10‐phenanthroline. In all three mutant strains, the increase in sensitivity to both aminoglycoside antibiotics was totally rescued by expressing NPA3. Protein synthesis, visualized by quantifying puromycin incorporation into nascent‐polypeptide chains, was markedly more sensitive to hygromycin B inhibition in npa3ΔC, npa3K16R, and npa3G70A than NPA3 cells. Notably, high‐copy expression of the TIF11 gene, that encodes the eukaryotic translation initiation factor 1A (eIF1A) protein, completely suppressed both phenotypes (of reduced basal cell growth and increased sensitivity to hygromycin B) in npa3ΔC cells but not npa3K16R or npa3G70A cells. We conclude that Npa3 plays a critical RNAPII‐independent and previously unrecognized role in translation initiation.
Do SWF investments matter for bond ratings? The role of corporate governance
Authors: Ouni Zeineb , Ghouma Hatem H. , Ben‐Nasr Hamdi
Published: March 2024

We investigate the impact of sovereign wealth funds (SWFs) equity ownership on bonds’ credit ratings of their target firms. Using a sample of 2045 bonds issued by 324 SWF target firms from 16 countries over the period 1996–2020, we find evidence linking SWF investments to lower likelihood of bond rating upgrades. Consistent with value‐reducing political agenda hypothesis, our results suggest that credit rating agencies perceive SWFs as a structure that could affect the quality of corporate governance and harm bondholder interests by leaving them vulnerable to losses. Our results also show that credit rating could be improved: (i) with SWF transparency and experience; (ii) when SWFs take a more passive investment stance; and (iii) within the financial crisis period. Finally, and interestingly, using generalized structural equation modelling, we provide evidence supporting the mediating role of target firm's corporate governance quality in the relationship between SWF investments and bond ratings. Our findings are robust to controls for the endogeneity and heteroscedasticity issues and to alternative sample compositions and regression frameworks.
The impact of shared value proposition on consumer engagement through a sense of brand community
Authors: Lin Jing , Long Chengzhi , Liu Bo
Published: March 2024

Creating shared value (CSV) literature has heralded enterprises generating economic benefit while simultaneously adding value to society. Existing research predominantly employs the case study method to show that enterprises adopting CSV strategies have achieved commercial success. However, empirical investigations are still rarely undertaken to examine the effect of CSV on consumers. This study argues that a shared value proposition generates consumer engagement (CE) and fosters in customers a sense of brand community. To this end, a moderated mediation model is constructed to delineate the relationship between shared value proposition, sense of brand community, and brand engagement. The empirical results show that a shared value proposition has a positive impact on brand engagement, which is fully mediated by consumers' sense of brand community. The study also discovered that consumers' self‐construal does not moderate the relationship between shared value proposition and sense of brand community. We hope our study and the evidence it provides help to shed more lights on the understanding and impact of CSV and to support the application of CSV strategy in enterprise.
Enhancing the quality and shelf life of semi‐smoked sausages with sesame seed additions
Authors: Serikkyzy Mira , Baybolova Lyazzat , Kulazhanov Talgat , Balev Desislav , Vlahova‐Vangelova Desislavа
Published: March 2024

This study investigates strategies to improve the quality and prolong the shelf life of semi‐smoked sausages made from beef by incorporating vegetable products. In this study, sesame seeds and sesame oil were employed as plant‐based products. Organoleptic analysis was comprehensively conducted, assessing sensory characteristics such as taste, aroma, texture and visual appearance of semi‐smoked sausages. Evaluations were performed by experienced experts, ensuring a meticulous and precise investigation of the sensory attributes of the product. The analysis encompasses a comprehensive examination of microbiological parameters over varying storage periods, a detailed study of the overall chemical composition, sensory evaluations and scrutiny of pH variations and oxidative processes during the 0–30 days storage interval. Distinct groups, including a control group (Group 1—sausages without vegetable additives), Group 2 (sausages with sesame seed incorporation) and Group 3 (sausages with sesame oil inclusion), were subjected to the experimental conditions. Evaluating the pH levels revealed a significant gradual increase in Group 3 compared to both the control (P ≤ 0.01) and Group 2 (P ≤ 0.05). Simultaneously, water activity values experienced a notable decrease to 0.944 (P ≤ 0.05) in all groups, providing a uniform trend across the experiment. The introduction of plant‐based ingredients, particularly sesame, and the comprehensive examination of various production technologies, encompassing both standard and accelerated processes, distinguish this study from existing works. Furthermore, the research takes into account a complex array of factors acting as barriers, providing valuable practical insights for potential improvements in the production of semi‐smoked sausages.
Dynamics of potential antihypertensive and antidiabetogenic activities during artisanal fermentation of three varieties of Mexican cocoa beans (Theobroma cacao L.)
Authors: Domínguez‐Pérez Leydy A. , Beltrán‐Barrientos Lilia M. , Torres‐Llanez María J. , González‐Córdova Aarón F. , Hernández‐Mendoza Adrián , García Hugo S. , Vallejo‐Cordoba Belinda
Published: March 2024

The aim of the present study was to follow the dynamics of potential antihypertensive (angiotensin‐converting enzyme (ACE)) and antidiabetogenic (dipeptidyl peptidase IV (DPP‐IV)) inhibitory activities during artisanal fermentation of Mexican cocoa beans. Almendra Blanca, Criollo and Forastero cocoa beans were sampled after 0, 48, 72, 96 and 120 h of fermentation and roasting (140 °C) and subjected to simulated gastrointestinal digestion. Subsequently, proteolytic activity (OPA method), peptide abundance (RP–HPLC), ACE and DPP‐IV inhibitory activities and IC50 were determined. The results showed that proteolytic activity, peptide abundance and ACE and DPP‐IV inhibition were higher (P < 0.05) at the final stages of fermentation (96 and 120 h). However, IC50 values in partially fermented (48 to 96 h) cocoa beans were the lowest (P < 0.05) of all. In conclusion, a partially fermented cocoa bean may be desirable for its use as a functional ingredient with potential antihypertensive and antidiabetogenic effects.
Cooking quality of rice is a potential predictor to identify low starch digestibility rice
Authors: Kumar Awadhesh , Biswal Monalisha , Sahoo Upasana , Nayak Lopamudra , Lal Milan Kumar , Sah Rameswar Prasad , Nayak Amaresh Kumar
Published: March 2024

Surge in diabetes cases and its expensive management cost are major constraints leading to reduced rice consumption. Therefore, screening of low glycaemic index (GI) rice along with better cooking quality is a cost‐effective approach for diabetes management. In 103 diverse rice germplasms analysed for starch digestibility parameters, GI was observed between 52.72 (EC 966576) and 73.46 (IC 200559), whereas resistant starch (RS) and amylose content (AC) were found in the range of 0.31–2.26% and 3.52–22.31%, respectively. On the other hand, water uptake (WU), gel consistency (GC) and alkali spreading value (ASV) were estimated to check possible linkage between these cooking quality parameters and starch digestibility. A significant positive correlation (r = 0.84, r = 0.95) was found between GI and ASV, WU. However, GC showed a significant negative correlation (r = −0.90) with GI. These cooking quality parameters can be used as an alternative approach to identify low‐starch digestibility rice.
Effect of high‐speed homogenisation on the morphological characteristics and survivability ofLactobacillus rhamnosusGG‐coated microbeads
Authors: Ali Umair , Saeed Muhammad , Ahmad Zulfiqar , Waseem Muhammad , Shah Faiz‐ul‐Hassan , Khan Muhammad Asif , Tariq Muhammad Rizwan , Hafeez Hammad , Kiran Warda , Nayik Gulzar Ahmad , Ramniwas Seema , Ansari Mohammad Javed , Alahmadi Tahani Awad
Published: March 2024

Xanthan gum can be utilised to overcome the structural defects in alginate microbeads and to improve the stability of microbeads under harsh conditions, that is, high acidic pH and homogenisation speeds. Present study was conducted to assess the survival ofLactobacillus rhamnosusGG using alginate (1.5% w/v) and xanthan gum (0.5% w/v) for encapsulation and structural modifications of microbeads. Homogenisation emulsion technique was used for encapsulation at various homogenisation speeds, that is, 3000 rpm (HS1), 6000 rpm (HS2), 9000 rpm (HS3) and 12 000 rpm (HS4). The resultant microbeads were characterised for diameter, beads yield, structural morphology using the scanning electron microscopy, probiotic count, bacterial survival, storage stability and homogenisation efficiency. Scanning electron microscopy images indicated that the beads produced at 12 000 rpm are more uniform, spherical in shape and have large surface area when compared with the other treatment groups. The diameter of microbeads was reduced from 323.1 to 238.2 μm as the homogenisation speed increased from 3000 to 12 000 rpm. The highest bacterial count (i.e., 9.45 log CFU g−1), homogenisation efficiency (91.6%), beads yield (23.0%), survivability (86.5%) and storage stability (9.84 to 7.90 log CFU g−1) were recorded at 12 000 rpm (HS4). Conclusively, the homogenised encapsulated microbeads at 12 000 rpm significantly improved the beads surface and sphericity, and bacterial survivability.
Characterisation and emulsifying properties of microwave pretreated camelina seed mucilage
Authors: Ozdemir‐Orhan Necla
Published: March 2024

In this study, microwave (MW)‐assisted extraction was used to obtain mucilage from Camelina sativa seeds. MW pretreatment was applied for 0, 2.5, 5 and 7.5 min and then conventional heating was conducted (55 °C for 2 h). The extracted mucilage was spray dried. The MW‐assisted extraction method (2.02%–2.50%) had higher extraction yield for camelina seed mucilage than the conventional heating method (1.91%) (P < 0.05). The emulsifying properties of the mucilages were compared with those of gum Arabic and all emulsions displayed shear thinning behaviour (pseudoplastic, n < 1). The apparent viscosity of the conventional, 2.5, 5 and 7.5 min MW mucilage emulsions were 15.83, 14.48, 7.91 and 7.56 cP, respectively, at 10 s−1. MW pretreatment improved physical stability and resulted in a reduction in the droplet size of mucilage‐stabilised emulsions with increasing process time. The highest droplet size belonged to the conventional mucilage emulsion (d32, 4.43 μm), while the lowest belonged to the 7.5 min MW mucilage emulsion (d32, 2.08 μm) (P < 0.05). The results highlight the advantages of using MW pretreatment for mucilage extraction and the potential of using camelina seed mucilage as a natural emulsifier.
Comparative analysis of process intensification technologies (PIT) for improved cell disruption and lipid recovery in Aurantiochytrium sp. SW1 microalgae
Authors: Mokhtar Nurdiana , Abdul Rahman Hafeedza , Sofian‐Seng Noor‐Soffalina , Lim Seng Joe , Wan Mustapha Wan Aida , Abdul Hamid Aidil , Mohd Razali Noorul Syuhada , Mohamed Nazir Mohamed Yusuf
Published: March 2024

This study explores enhancing lipid recovery from the lipid‐rich marine microalgae Aurantiochytrium sp. SW1, known for its robust cell wall posing challenges, which necessitates energy‐intensive cell‐disruption for efficient intracellular lipid extraction. Despite advancements in other microalgae, there is lack of reports on efficient cell disruption for Aurantiochytrium sp. SW1 which is vital to reduce the energy costs and minimising the downstream process while maximising lipid yields. Three process intensification technologies (PIT) – microwave treatment, autoclave treatment and ultrasonication were employed on wet Aurantiochytrium sp. SW1 cells to improve the lipid extraction efficiency. Assessing the disruption effectiveness via lipid content, suspension turbidity and particle size distribution, alongside scanning electron microscopy (SEM) for cellular morphology changes post‐PIT treatments, this study indicates all three methods reduced particle size with prolonged treatment time, implying successful cell wall disruption and intracellular component release. Ultrasonication, especially at 50 W power for 10 min, exhibited the highest efficacy, yielding lipid content of 67.76 ± 0.03%. Microscopic analysis unveiled ultrasonication‐induced cell shrinkage and increased membrane permeability, supporting its effectiveness in enhancing solvent penetration for improved lipid recovery. This research underscores PIT techniques' potential as sustainable, energy‐efficient strategies for lipid extraction from Aurantiochytrium sp. SW1 microalgae.
Development of non‐dairy creamer with modified fatty acid profile and high Omega‐3 and 6 at a non‐dairy creamer plant
Authors: Punvichai Teerasak , Wachiratreeyakul Tharawee , Pipakdee Jantarat , Kaewsatorn Wandee , Kritsanapuntu Sirusa , Chotimarkorn Chatchawan , Pianroj Yutthapong , Detarun Preeyabhorn
Published: March 2024

A study was conducted to develop non‐dairy creamer production with a modified fatty acid profile having high levels of omega‐3 and 6, by using raw materials collected from the Republic Foods industrial non‐dairy creamer plant. The non‐dairy creamer formulation aimed to maintain a balanced 1:1:1 ratio of polyunsaturated, monounsaturated and saturated fatty acids. The ingredients used included palm olein, stearin, RBD palm oil, rice bran oil, soybean oil, coconut oil and palm kernel oil. The mixture proportions tested were determined using Design Expert software, for in total 20 different formulations. From these, six formulations were selected based on their fatty acid profiles, which closely approximated the desired 1:1:1 ratio of polyunsaturated, monounsaturated and saturated fatty acids. To complement the physicochemical results, a quality control and research officer from Republic Foods industrial conducted a comprehensive evaluation of various properties of the non‐dairy cream samples intended for use in coffee. It is noteworthy that formulation number 20 received the highest scores across all tested properties. This formulation had 50.53% palm olein, 1.00% stearin, 1.00% RBD palm oil, 1.00% rice bran oil, 44.47% soybean oil, 1.00% coconut oil and 1.00% palm kernel oil. This combination results in a fatty acid ratio of 1:1:0.8 (PUFA:MUFA:SFA) at the least production cost. The developed non‐dairy creamer exhibited the highest total energy content, namely 519 kilocalories/100 g, when compared with commercial brands. However, after a storage period of 90 days, the peroxide value reached 6.18 ± 0.22 mEq kg−1 of fat, which is below the FDA standard limit of 10.0 mEq kg−1 fat. This trend in peroxide value increase over the 90‐day storage period aligns with the behaviour of TBA, which also showed an upward trend during storage.
Bibliometric mapping analysis of Pickering emulsion applied in 3D food printing
Authors: de Farias Patrícia Marques , Matheus Julia Rabelo Vaz , Maniglia Bianca Chieregato , Le‐Bail Patricia , Le‐Bail Alain , Schmid Markus , Fai Ana Elizabeth Cavalcante
Published: March 2024

Three‐dimensional food printing (3DFP) can produce foods with tailored nutritional content, complex shapes and textures. This technology requires food formulations (food inks) with specific rheological properties. Pickering emulsions (PE) have gained attention due to their long‐term stability and desirable printable properties, making them an excellent candidate for 3DFP. The purpose of this study is to use bibliometric analysis to identify the most important scientific research on PE used in 3DFP. This includes identifying key authors, countries and universities or institutions where the research was conducted, as well as the primary journals that provide information on this topic. Our study provides insight into the relevance of food ink properties for next‐generation 3DFP and the main raw materials used for the development of PE. Out of the 28 original research articles analysed, only 10 countries have studied the application of PE for 3DFP. China and the United Kingdom have been the primary leaders in researching this topic. The Food Hydrocolloids Journal has been the main source of scientific information. The studies cited Pickering stabiliser particles, including soy protein isolate, microcrystalline cellulose and acetylated microcrystalline cellulose, as well as oil phases based on sunflower, canola, olive and soybean oils. High internal phase Pickering emulsions (HIPPEs) have shown great thermal and conductive stability, making them a promising choice for 3DFP post‐processing. Further studies should assess the bioavailability and bioaccessibility of the bioactive compounds that are encapsulated. It is also important to explore their potential use in real food systems and to integrate innovative packaging solutions.
In silico bioactivity analysis of peptide fractions derived from brewer's spent grain hydrolysates
Authors: Aguilar‐Toalá J. E. , Cruz‐Narváez Y. , Quintanar‐Guerrero D. , Liceaga Andrea M. , Zambrano‐Zaragoza M. L.
Published: March 2024

Brewer's spent grain is an agro‐industrial waste of barley malt from the manufacture of beer, which is rich in protein. Thus, this by‐product of the beer industry could be utilised to obtain bioactive peptides through enzymatic hydrolysis. The present study aimed to evaluate potential bioactivities (anti‐inflammatory, antidiabetic, antioxidant, antimicrobial) of peptide sequences identified in 5‐kDa peptide fractions derived from brewer's spent grain hydrolysates. Two experimental hydrolysates (run 5 and run 21) were selected based on their higher degree of hydrolysis (>55%), which were subjected to peptide sequence identification and used for in silico analysis. A total of fifty peptide sequences were identified between both runs. In silico analysis identified seventeen and thirteen multifunctional peptides in runs 5 and 21, respectively, which showed between two and four potential bioactivities. Interestingly, one peptide sequence (DLPPER) showed four potential bioactivities and, according to the Docking analysis, showed better Vina scores towards the protein's targets DPP‐IV (antidiabetic) and glucocorticoid receptor (anti‐inflammatory). These results demonstrate that peptides from brewer's spent grain hydrolysates may contribute to improving human health by offering potential protection against some chronic‐related diseases; however, further follow‐up in vitro and in vivo studies are needed to evaluate its actual capability.
Excess control of family board seats and corporate innovation
Authors: Chen Suyun , Li Zongze , Chu Lingling , Cao Qingzi
Published: March 2024

We examine the impact of board‐level control on corporate innovation in family firms. We find that excess control of family board seats (ECFBS) is negatively correlated with innovation investment, innovation output and innovation efficiency. Our findings suggest that ECFBS exacerbates type II agency problems. Mechanistic analyses show that ECFBS reduces firms’ risk‐taking level, increases their financing constraints and damages channels for acquiring innovative professional knowledge. We also observe that effect of ECFBS on innovation is associated with family origin, familiarization time and family management characteristics. Our findings should be of interest to family firm manager investors and lenders who are interested in family governance mechanisms.
TV cooking shows—Consumer entertainment or education?
Authors: Ovca Andrej , Žižek Nastja , Jevšnik Mojca
Published: March 2024

The current observational study aims to determine the extent to which main food safety principles are addressed in Slovenian cooking shows and whether the type of main actor or television channel significantly impacts adherence to good hygiene practices. In general, our results show that food handling presented to the audience in Slovenian TV cooking shows often deviates from the main food safety recommendations. A comparison between amateur and professional chefs has shown notable but statistically insignificant differences. While in the area of personal hygiene, more deviations were found among amateur than among professional chefs (p = 0.011), we can observe the opposite in the area of preparation practices, albeit with insignificant difference (p = 0.884). The current study provides further evidence that there is a large gap between what viewers see and what they should have seen in television cooking shows from a food safety perspective.
Some habits are more work than others: Deliberate self‐regulation strategy use increases with behavioral complexity, even for established habits
Authors: Saunders Blair , More Kimberly R.
Published: March 2024

Objective

We tested the hypothesis that complex behaviors are commonly supported by self‐regulation strategies, even when those behaviors are supported by strong instigation habits.

Background

Goal‐directed and habit‐mediated processes arise from separable systems that have been suggested to seldomly interact.

Results

Self‐regulation strategy use was lower for habitually instigated simple behaviors compared to nonhabitually instigated simple behaviors. However, participants' use of self‐regulation strategies increased with the increasing complexity of behaviors, even when complex behaviors were habitually instigated. The difference in the extent of strategy use between habitually and nonhabitually instigated actions was absent when behavioral complexity was particularly high.

Conclusion

These results point to a qualitative distinction—while simple behaviors may progress in a relatively automatic and unthinking manner, complex behaviors receive frequent support from self‐regulation strategies, even if they are instigated habitually.
Influence of mental and behavioral factors on weight loss after bariatric surgery: A systematic review and meta‐analysis
Authors: Jacobs Anne , Monpellier Valerie M. , Torensma Bart , Antoniou Evangelia E. , Janssen Ignace M. C. , Tollenaar Rob A. E. M. , Jansen Anita T. M.
Published: March 2024

Introduction

Multiple factors are related to lower weight loss after bariatric surgery. This review and meta‐analysis evaluates the influence of several mental and behavioral factors on weight loss.

Method

Six electronic databases were searched. Percentage excess weight loss (%EWL) was calculated for all moderator and non‐moderator groups of the variables: symptoms of depression, anxiety and binge eating, compliance, physical activity, quality of life, and body image. All moderators, surgery types, and follow‐up moments were analyzed separately.

Results

In total, 75 articles were included in the review; 12 meta‐analyses were conducted. Higher postoperative compliance to follow‐up was associated with 6.86%–13.68% higher EWL. Preoperative binge eating was related to more weight loss at 24‐ and 36‐month follow‐up (7.97% and 11.79%EWL, respectively). Patients with postoperative binge eating symptoms had an 11.92% lower EWL. Patients with preoperative depressive symptoms lost equal weight compared to patients without symptoms.

Conclusion

Despite the high heterogeneity between studies, a trend emerges suggesting that the presence of postoperative binge eating symptoms and lower postoperative compliance may be associated with less weight loss after bariatric‐metabolic surgery. Additionally, preoperative depressive symptoms and binge eating do not seem to significantly impact weight loss.
Development and characterization of a cell donor registry for virus‐specific T cell manufacture in a blood bank
Authors: Rudilla Francesc , Carrasco‐Benso María Paz , Pasamar Helena , López‐Montañés María , Andrés‐Rozas María , Tomás‐Marín Maria , Company Desirée , Moya Cristina , Larrea Luis , Guerreiro Manuel , Barba Pere , Arbona Cristina , Querol Sergio
Published: March 2024

Adoptive cell therapy using virus‐specific T cells (VST) is a strategy for treating common opportunistic viral infections after transplantation, particularly when these infections do not resolve through antiviral drug therapy. The availability of third‐party healthy donors allows for the immediate use of cells for allogeneic therapy in cases where patients lack an appropriate donor. Here, we present the creation of a cell donor registry of human leukocyte antigen (HLA)‐typed blood donors, REDOCEL, a strategic initiative to ensure the availability of compatible cells for donation when needed. Currently, the registry consists of 597 healthy donors with a median age of 29 years, 54% of whom are women. The most represented blood groups were A positive and O positive, with 36.52% and 34.51%, respectively. Also, donors were screened for cytomegalovirus (CMV) and Epstein–Barr virus (EBV). Almost 65% of donors were CMV‐seropositive, while less than 5% were EBV‐seronegative. Of the CMV‐seropositive donors, 98% were also EBV‐seropositive. High‐resolution HLA‐A, ‐B, ‐C, ‐DRB1 and ‐DQB1 allele and haplotype frequencies were determined in the registry. Prevalent HLA alleles and haplotypes were well represented to ensure donor‐recipient HLA‐matching, including alleles reported to present viral immunodominant epitopes. Since the functional establishment of REDOCEL, in May 2019, 87 effective donations have been collected, and the effective availability of donors with the first call has been greater than 75%. Thus, almost 89% of patients receiving an effective donation had available at least 5/10 HLA‐matched cell donors (HLA‐A, ‐B, ‐C, ‐DRB1, and ‐DQB1). To summarize, based on our experience, a cell donor registry from previously HLA‐typed blood donors is a useful tool for facilitating access to VST therapy.
ENSEMBLE CLASSIFIER BASED FAKE NEWS IDENTIFICATION IN ONLINE SOCIAL NETWORK
Authors: R Sandrilla , Devi Savitha
Published: March 2024

In today’s context, one of the main mediums of news consumption is through social media. It has become a common trend now to produce fake news for speedy propagation and popularity. Thus, it creates a sort of illusion and deception for readers.  Amidst the umpty number of researches done, we could say that there is no research that could accurately predict fake news over online. In this study, the ensemble classifier is employed to develop a model for fake news identification in online social networks. This proposed method applies the stacked ensemble classification model, the proposed approach that learns the represented text model and classifies the textual data into real news and fake news. Then, the proposed approach takes the collaborative decision from the classified data that is generated from the multiple base learners using the weight-based ensemble method. The accuracy prediction and performance evaluation of time consumption of detection fake news are consecutively 80 Percentage and 11 ms respectively.  Thus, it improves the efficiency and classification accuracy over large-scale social media messages through an efficient sentiment analysis model.
INTERFACE SHEAR STRENGTH DEGRADATION IN PROGRESSIVE LANDSLIDE OF WEATHERED CLAY SHALE OVERBURDEN ON UNDISTURBED CLAY SHALE
Authors: Sagitaningrum Fathiyah Hakim , Kamaruddin Samira Albati , Nazir Ramli , Soepandji Budi Susilo , Alatas Idrus Muhammad
Published: March 2024

In accomplishing Sustainable Development Goals (SDGs), the construction of roads played a substantial role in achieving economic equity. However, landslides due to problematic soil would hinder its construction process. Thus, it is essential to understand the mechanism of slope movement to reduce landslide problems. A landslide that happened during the construction of the Semarang-Bawen toll road was analyzed in this research. The landslide was known to fail between the interface of the tuff breccia overburden and the problematic clay shale soil. This research proposed the direct shear test to determine the interface shearing behavior. Before the test, the overburden was differentiated as various sand and weathered clay shale ratios. After the overburden soils were compacted, a multistage interface direct shear test was conducted with three different loadings. Water was added to the overburden layer to model the infiltration at the interface by increasing the water content. From the test, results such as the interface cohesion, friction angle, and average stress ratio were obtained. Overall, the interface shear strength decreased as the water content increased. The decreasing value was due to the wetting at the interface. Thus, it would moisten the interface and disrupt the structure of both the top and bottom layers of the sample. In conclusion, the interface direct shear test was able to describe the shear behavior at the clay shale interface. It also indicated that water had a considerable role in triggering interface landslides for two different soil layers.
SOCIO-ECONOMIC DEVELOPMENT INDICES AND THEIR REFLECTION ON INTERNET PERFORMANCE IN ASEAN COUNTRIES
Authors: Habbal Adib , Mkpojiogu Emmanuel O.C. , Cottrell Les , White Bebo , Hassan Suhaidi , Zulhumadi Faisal
Published: March 2024

Despite Internet use rapidly accelerating in ASEAN countries, its penetration rate across member countries varies from 84.45% of the population in Singapore to roughly 21.87% in Laos. This digital divide portends profound consequences on the social-economic development of the region. Therefore, this article describes an Internet performance study conducted within ASEAN countries using actual Internet performance data collected from 2000 to 2019 generated by the PingER Project. The results showed that the pattern of Internet performance (IP) is that the most developed countries have the best Internet performance, whereas the least developed ones have the lowest Internet performance. These Internet performance data were then compared and analyzed against several selected social-economic development indices in order to observe any trends and establish observable relationships. Initial inspection indicated a possible relationship between Internet performance and the indices, which was then statistically tested further by correlation and regression. Next, the relationship was then represented by a regression model, which was then validated through R2 and graphical residual analysis. As a result, this study has proposed a novel model that provides an insight into the influence of social-economic development indices on Internet performance in ASEAN countries.
ASSESSMENT OF ROCK MASS QUALITY AND ROCKFALL POTENTIAL EVALUATION FOR RECLAMATION OF A QUARRY
Authors: Hussin Hamzah , Arifin Mohd Hariri , Rusydy Ibnu , Lai Goh Thian , Udin Wani Sofea
Published: March 2024

In order to make an informed decision about implementing sustainable and efficient development during land reclamation in an area deemed geohazard-prone, thorough geological input is necessary. Quarry areas are vulnerable to slope failure and rockfalls, making it imperative to evaluate rock slopes for quarry reclamation. For this reason, researchers in Kinta Valley, Malaysia, set out to evaluate the slopes GG1, GG2, and GG3 at a defunct quarry. To evaluate the rock mass classification, the Rock Mass Rating (RMR) and Slope Mass Rating (SMR) systems were utilized, and the analyzing rock block's trajectory was using a rockfall analysis. The kinematic stability analysis was also performed to identify possible failure mechanisms. In order to assess the site's suitability for urban development, the rockfall scenarios were conducted. The SMR scaled from moderate to very good, while the RMR ranked the rock mass quality as good to very good. For all three of the slopes analyzed, the kinematic stability analysis pointed to the possibility of various failures (toppling, planar and wedge). According to the rockfall trajectory analysis, the rock block could roll as far as 5 metres from the base of the slope. For this reason, the study advised creating a buffer zone of 20 metres or more away from the rock slope as a means of protection against the geohazard of rockfall.
FEASIBILITY ANALYSIS OF HYDROGEN-FREE DEOXYGENATION REACTIONS OF PALMITIC ACID TO HYDROCARBONS FUELS THROUGH THERMODYNAMIC STUDIES
Authors: Riyanto Teguh , Istadi I. , Anggoro Didi D. , Jongsomjit Bunjerd
Published: March 2024

Four models were investigated to study the feasibility of the hydrogen-free deoxygenation of palmitic acid to hydrocarbons through the stoichiometric thermodynamic equilibrium analysis. The reaction conditions have been varied to estimate the equilibrium reactions composition (temperature (T) of 200 – 600 °C, pressure (P) of 1 – 20 bar, and H2/Palmitic acid ratio of 0 – 10). It was found that the hydrogen-free deoxygenation of palmitic acid was thermodynamically favorable with complete conversion (≈100%) at all investigated reaction conditions. The equilibrium products composition was significantly affected by reaction temperature. The main-formed hydrocarbon was C15H­32 at low temperatures and C15H30 at high temperatures. However, the product composition of reaction equilibrium was not affected by the reaction pressure. Even though the internal hydrogen was generated, the hydrodeoxygenation reaction pathways were not too favorable because the hydrodeoxygenation product and its intermediates were negligible.
DESIGNING OF DYNAMIC SURFACE CONTROL BASED ON BACKSTEPPING TECHNIQUE FOR SERIES ELASTIC ACTUATOR ROBOT
Authors: Duong Minh-Duc , Tran Thanh Tung
Published: March 2024

Serial elastic actuators have gained significant attention in robotics research due to their ability to meet safety requirements in physical interactions between humans and robots. However, one problem of series elastic actuator is the oscillation of the robot due to the flexibility of the robotic joints leading to a decline in the accuracy of the robot’s position control. In this paper, a dynamic surface control algorithm based on the backstepping technique for the position control of serial elastic actuator robot is proposed to overcome the oscillation problem. In addition, the proposed control algorithm has been proved to be stable and robust. The simulation results clearly demonstrate the effectiveness of the proposed method.
ESTIMATING AND ANALYZING COVID-19 TRANSMISSION IN THAILAND THROUGH DEEP NEURAL NETWORK
Authors: Wongsathan Rati , Puangmanee Wutthichai
Published: March 2024

The COVID-19 pandemic has caused significant global suffering and mortality, and effective control measures have been elusive. This study aims to develop an accurate and reliable prediction model using deep neural networks (DNN) to estimate the epidemic size and trends of COVID-19 cases, as well as the effective reproduction number, R(t). The efficacy of various control measures for COVID-19 has been questioned, and an efficient prediction model can aid in decision-making and planning. Overfitting is a common issue in neural networks, which can limit their accuracy and reliability. A modified dropout regularization technique and particle swarm optimization (PSO) are employed to enhance the accuracy of the DNN. The proposed model outperforms conventional neural networks and previous studies in terms of accuracy and reliability. The estimated R(t) values are consistent with measured values, which demonstrates the usefulness of this model in analyzing the situation and informing effective intervention strategies. The developed dropout-DNN-PSO model is an accurate and reliable predictor of COVID-19 trends and R(t) values. It can aid decision-makers in planning and implementing effective control measures. The proposed model can be extended to other countries to analyze and predict the trends of COVID-19 cases.
MONITORING THE ABSENCE OF QUEEN BEE IN THE HIVE USING DEEP LEARNING AND HILBERT HUANG TRANSFORM
Authors: Nguyen Ba Nghien , Kim Phuong Pham Thi , Thanh Huan Tran , Le Anh Thang , Van Trung Doan , Hong Phan Thi Thu
Published: March 2024

In this paper, we present a fusion method to monitor the absence of the queen bee in a hive using a combination of deep learning neural networks, support vector machine (SVM), and Hilbert Huang transform. First, we collect the sound data from the hive in the presence and missing of the queen bee using the Internet of Things system (IoT). Next, we slice the received audio signal into small chunk with a duration of 10 seconds. In the next step, we perform the Hilbert Huang Transform on each chunks to obtain the spectral image of the audio signal with and without the queen bee. Finally, we use the obtained spectral images to train and test the deep learning neural networks model combined with a support vector machine (SVM) to classify the spectral image of the audio signal with and without the queen bee. The test results on the test set achieved a classification accuracy of 98.61%.