bluuebunny/crossref_metadata_2025 huggingface dataset:
Correction: Thioamide quenching of intrinsic protein fluorescence
Authors: Goldberg Jacob M. , Wissner Rebecca F. , Klein Alyssa M. , Petersson E. James
Published: March 2020

Correction for ‘Thioamide quenching of intrinsic protein fluorescence’ by Jacob M. Goldberg et al., Chem. Commun., 2012, 48, 1550–1552.
Correction: Fabrication of red blood cell membrane-camouflaged Cu2−xSe nanoparticles for phototherapy in the second near-infrared window
Authors: Liu Zhou , Wang Jinquan , Qiu Kangqiang , Liao Xinxing , Rees Thomas W. , Ji Liangnian , Chao Hui
Published: March 2020

Correction for ‘Fabrication of red blood cell membrane-camouflaged Cu2−xSe nanoparticles for phototherapy in the second near-infrared window’ by Zhou Liu et al., Chem. Commun., 2019, 55, 6523–6526.
Exploring the origins of crystallisation kinetics in hierarchical materials using in situ X-ray diffraction and pair distribution function analysis
Authors: Potter Matthew E. , Light Mark E. , Irving Daniel J. M. , Oakley Alice E. , Chapman Stephanie , Chater Philip , Cutts Geoff , Watts Andrew , Wharmby Michael , Vandegehuchte Bart D. , Schreiber Moritz W. , Raja Robert
Published: March 2020

Novel in situ synchrotron total scattering measurements probe the assembly of primary building units into templated hierarchically porous aluminophosphate catalysts, providing unique insights to understanding crystallisation kinetics.
Rh(i)-Catalyzed enantioselective and scalable [4 + 2] cycloaddition of 1,3-dienes with dialkyl acetylenedicarboxylates
Authors: Bao Robert Li-Yuan , Yin Junjie , Shi Lei , Zheng Limin
Published: March 2020

A highly enantioselective and scalable intermolecular [4 + 2] cycloaddition to construct substituted cyclohexa-1,4-dienes.
Development of novel C-nucleoside analogues for the formation of antiparallel-type triplex DNA with duplex DNA that includes TA and dUA base pairs
Authors: Taniguchi Yosuke , Magata Yuya , Osuki Takayuki , Notomi Ryotaro , Wang Lei , Okamura Hidenori , Sasaki Shigeki
Published: March 2020

We report the formation of stable triplex DNA for TA duplex sites by using triplex-forming oligonucleotides (TFOs) with novel C-nucleoside analogues.
Correction: Synthetic approaches for multiblock copolymers
Authors: Beyer Valentin P. , Kim Jungyeon , Becer C. Remzi
Published: March 2020

Correction for ‘Synthetic approaches for multiblock copolymers’ by Valentin P. Beyer et al., Polym. Chem., 2020, 11, 1271–1291.
High-performance capacitive strain sensors with highly stretchable vertical graphene electrodes
Authors: Deng Caihao , Lan Linfeng , He Penghui , Ding Chunchun , Chen Baozhong , Zheng Wei , Zhao Xin , Chen Wangshou , Zhong Xizhou , Li Min , Tao Hong , Peng Junbiao , Cao Yong
Published: March 2020

A stretchable capacitive strain sensors based on vertical graphene electrodes with unique stress direction recognizing ability is demonstrated, showing potential to detect physical and physiological signals.
Neutral pH aqueous redox flow batteries using an anthraquinone-ferrocyanide redox couple
Authors: Lee Wonmi , Permatasari Agnesia , Kwon Yongchai
Published: March 2020

Anthraquinone-2,7-disulfonic acid (2,7-AQDS) and ferrocyanide including potassium and sodium salts are used as a redox couple for neutral aqueous redox flow batteries (ARFBs).
Topology optimised fixed‐time consensus for multi‐UAV system in a multipath fading channel
Authors: Hao Lei , Qi Xiaohan , Yang Zhihua
Published: March 2020

Time‐varying connectivity is one of main challenges faced by controlling a team of unmanned aerial vehicles (UAVs) in the multipath fading channel, incurring low accuracy and significant convergence time of formation control law. To address this issue, in this study, a topology optimised based decentralised consensus is developed for controlling a multi‐UAV system in a multipath fading channel, in which a formation structure reconfiguration scheme is proposed as well as a transmission power allocating algorithm to guarantee the control accuracy in a limited convergence time. In particular, the objective function for topology optimisation is well‐designed by considering the second eigenvalue of Laplacian matrix of topology as a feasible index of connectivity degree. To improve the efficiency of information transmission, a specified consensus protocol is proposed with well‐tailored packet format and signalling procedure for control messages. Through the comparative simulation results, the proposed consensus can achieve high convergence accuracy and less convergence time in a multipath fading channel, indicating high resilience of the proposed protocol under a multipath fading channel.
Adaptive Particle Swarm Optimisation based Energy Efficient Dynamic Correlation Behavior of Secondary Nodes in Cognitive Radio Sensor Networks
Authors: Mukherjee Amrit , Goswami Pratik , Yan Ziwei , Yang Lixia
Published: March 2020

Wireless sensor network enhances the classic features of wireless communication with cognitive capabilities for efficient spectrum usage. This work focuses on the dynamic correlation between the secondary users (SUs) based on their statistical behaviour while performing the cooperative communication in cognitive radio sensor network. The proposed approach addresses the problem of uneven and repetitive communication between the SUs in a cooperative communication scenario. The authors’ objective is to use a novel approach based on the Gaussian copula theory and advanced particle swarm optimisation algorithm to analyse the dependencies of time‐varying spectrum sensing behaviour of multiple SUs. Here, time delay in prediction reduces due to the analysis of the dynamic correlation between the time delay in spectrum sensing results for the same set of channels. The simulation results show the performance of the proposed approach outperforming the other well‐known techniques.
Optimal power allocation for non‐orthogonal multiple access in wireless backhaul networks
Authors: Yang Xiaoqi , Hua Cunqing , Xu Wenchao , Gu Pengwenlong
Published: March 2020

In this study, the authors adopt the non‐orthogonal multiple access (NOMA) technique to improve the spectrum efficiency in the wireless backhaul networks, whereby the downlink and uplink NOMA techniques are applied for the backhaul and access links, respectively. Due to the coupling between the backhaul and access transmission stages, the transmission power should be carefully allocated in both stages so that the overall throughput can be maximised. They start with the single user equipment (UE) case and consider different scenarios and analyse the tradeoff between the access and backhaul links, and the optimal power allocation solutions are obtained accordingly. They then extend the analysis to the multi‐UE case and formulate the optimal power allocation problem, which is solved using the Lagrangian dual decomposition algorithm. Simulation results demonstrate that the proposed schemes are effective in improving the throughput and outperforms the conventional orthogonal multiple access technique under different network settings.
Offline method for experimental identification of load‐dependentsaturation of induction motor taking into account variation of inverse rotortime constant
Authors: Lipcak Ondrej , Bauer Jan
Published: March 2020

Accurate knowledge of induction machine parameters has a direct impact on theoverall performance of field‐oriented control strategies. In the case of rotorflux oriented control, parameter mismatch causes a discrepancy in the estimatedrotor flux position and amplitude. Magnetising inductance is one of theparameters whose detuning has a direct impact on the setpoints of the controlloops and estimation of hardly or non‐measurable quantities. Conventional ironsaturation, which can be obtained by a standard no‐load test, is not the onlytype of saturation occurring in the machine. Depending on the rotor design, themagnetising inductance and the rotor leakage inductance may also stronglysaturate as a function of load and, thus, rotor current. Based on the authors’previous work, a new, improved experimental method for identifying theload‐dependent saturation of induction motor, which takes into account variationof the inverse rotor time constant, is proposed. Experimental results conductedon 12 kW motor show improved static and dynamic behaviour of the drive comparedto the constant parameter model.
Centralised secondary control for islanded microgrids
Authors: de Nadai Nascimento Bruno , Zambroni de Souza Antonio Carlos , Marujo Diogo , Sarmiento Jonattan Emanuel , Alvez Cristian Adolfo , Portelinha Francisco Martins , de Carvalho Costa João Guilherme
Published: March 2020

Electric power systems have undergone substantial changes in their operation. The higher penetration of renewable resources, demand response capability, and generators operating via droop control at the distribution level are the main features resulting in the microgrid concept. Microgrids must operate connected or islanded from the main grid, ensuring reliability and quality in the supply of energy in both operating scenarios. In this sense, the secondary control becomes essential in the system's resilience, since it is responsible for restoring the frequency and voltage within acceptable values. This study proposes a unified frequency and voltage secondary controls for microgrids operating in islanded mode. For this sake, a modification in the load flow algorithm considering a Jacobian matrix takes place, enabling a sensitivity analysis to give the adjustments in the set point of generators. The help of the Levenberg–Marquardt method improves the convergence in the modified load flow. All generators are continuously considered in this process, regarding their capabilities and relative control sensitivities concerning the operation point restoration. The proposed methodology is validated in a modified IEEE‐37 node test feeder, showing the efficacy of the centralised secondary control under different scenarios of renewable generation penetration and load levels.
Ultra‐high‐speed non‐unit non‐differential protection scheme for buses of MMC‐HVDC grids
Authors: Farshad Mohammad
Published: March 2020

Half‐bridge modular multilevel converter‐based high‐voltage direct‐current (MMC‐HVDC) grids are technically and economically viable solutions to transmit bulk electrical energy generated from geographically dispersed and remote renewable resources. However, due to the half‐bridge converter's inability to control fault currents, these grids need specialised protection schemes to increase reliability and equipment safety. This study proposes a non‐unit non‐differential protection scheme founded on a comparative orientation measure of fault components for buses of half‐bridge MMC‐HVDC grids. Considering the selected protection strategy, the protection zone of this scheme can also cover a part of the converter station's ac side; in which severe short‐circuit faults should be quickly detected and isolated as well since they may cause the entire grid outage. This scheme can be used as the main protection or a backup of the conventional differential current protection, and subsequently, increase the protection system dependability by increasing the functional diversity. The test results disclose that the proposed scheme has superior sensitivity to identify single‐pole and double‐pole faults with resistances up to 1500 and 2000 Ω, respectively, at the protected dc bus with the maximum delay of 1 ms, while it is robust against all ac and dc faults outside the designated protection zone.
An imaging line survey of OMC-1 to OMC-3
Authors: Brinkmann N. , Wyrowski F. , Kauffmann J. , Colombo D. , Menten K. M. , Tang X. D. , Güsten R.
Published: March 2020

Context. Recently, sensitive wide-bandwidth receivers in the millimetre regime have enabled us to combine large spatial and spectral coverage for observations of molecular clouds. The resulting capability to map the distributions of lines from many molecules simultaneously yields unbiased coverage of the various environments within star-forming regions.

Aims. Our aim is to identify the dominant molecular cooling lines and characteristic emission features in the 1.3 mm window of distinct regions in the northern part of the Orion A molecular cloud. By defining and analysing template regions, we also intend to help with the interpretation of observations from more distant sources which cannot be easily spatially resolved.

Methods. We analyse an imaging line survey covering the area of OMC-1 to OMC-3 from 200.2 to 281.8 GHz obtained with the PI230 receiver at the APEX telescope. Masks are used to define regions with distinct properties (e.g. column density or temperature ranges) from which we obtain averaged spectra. Lines of 29 molecular species (55 isotopologues) are fitted for each region to obtain the respective total intensity.

Results. We find that strong sources like Orion KL have a clear impact on the emission on larger scales. Although not spatially extended, their line emission contributes substantially to spectra averaged over large regions. Conversely, the emission signatures of dense, cold regions like OMC-2 and OMC-3 (e.g. enhanced N2H+ emission and low HCN/HNC ratio) seem to be difficult to pick up on larger scales, where they are eclipsed by signatures of stronger sources. In all regions, HCO+ appears to contribute between 3 and 6% to the total intensity, the most stable value for all bright species. N2H+ shows the strongest correlation with column density, but not with typical high-density tracers like HCN, HCO+, H2CO, or HNC. Common line ratios associated with UV illumination, CN/HNC and CN/HCO+, show ambiguous results on larger scales, suggesting that the identification of UV illuminated material may be more challenging. The HCN/HNC ratio may be related to temperature over varying scales.
Research priority of the potential earthquake on the java island using decision making analysis
Authors: Lestari Wien , Widodo Amien , Syaifuddin Firman , Warnana Dwa Desa
Published: March 2020

Referring to the Indonesian earthquake source and hazard map published by the National Earthquake Center (Pusgen) in 2017, it was stated that there were 34 active faults on the island of Java and could potentially be a source of earthquakes with earthquake strength more than the 6.5 M scale. Each potential source of earthquake needs to be carried out detailed research on each fault that is declared active so as to reduce uncertainty in the seismic hazard analysis. Due to limited funding and human resources researching, it is necessary to make research priorities based on the level of urgency. By utilizing decision making analysis techniques, priority of research is carried out by considering several aspects, such as the magnitude of the earthquake that may occured possible economic impact factors, population density and the level of importance of a region on a national and international scale. From the modeling results, it is shown that faults that have the potential to become earthquake sources that are located near large cities are a top priority for detailed research such as the Lembang, Semarang and Surabaya Faults.
Pandeglang regency spatial evaluation based on tsunami hazard potential
Authors: Nauval Majid Roihan , Nurlambang Triarko
Published: March 2020

The coastal area of Pandeglang Regency is one area that has the potential to be affected by the tsunami. The existence of the Krakatau Anak Volcano and plate subduction paths in the Sunda Strait cause Pandeglang Regency to become one of the regions that has a tsunami potential. One of the steps to anticipate the tsunami disaster is to do spatial planning that has considered the potential tsunami hazard. The purpose of this research is to evaluate the spatial area of Pandeglang Regency based on the identification of potential tsunami hazards. The identification of potential tsunami hazards is done by modeling the potential distribution of tsunami wave heights in coastal areas using GIS modeling. The results of the identification of potential tsunami hazards on the coast of Pandeglang Regency showed that an area of 194.15 hectares of residential land and the location of existing activities had the potential to be affected by the tsunami. The total area of the coastal area of Pandeglang Regency which was potentially affected by the tsunami hazard reached 1483.26 hectares. The results of a review of the Pandeglang Regency's spatial plan showed that 488.22 hectares of land were found in the planned residential spatial patterns that were potentially affected by the tsunami. Therefore, the regional spatial plan of Pandeglang Regency in the study area needs to be evaluated by changing the function of residential land that has the potential to be affected by the tsunami hazard to the border of the beach or other open land.
The analysis of performance level on an existing multi-story building structure using the time history based on the subduction earthquake source
Authors: Erlangga Wisnu , Teguh Mochamad , Makrup Lalu
Published: March 2020

The use of time history in the building evaluation process is rarely done. Usually, the time history used is taken from a different location, with the building being evaluated so that the evaluation results become less valid. Each place has a different time history character that is why the analysis of structures using time history from other sites is not accurate. In this study, the time history used was sourced from subduction earthquake sources. For the time history used in the location of the study, a spectral matching process is needed to equalize the response spectra of the time history with the response spectra at the study location. The Alana Hotel is selected as a research object for building evaluation adopting SNI 03-1726-2012, FEMA 356, and ATC-40 as references with structural modeling using SAP2000. Based on the evaluation results, it can be summarized that displacement values at each floor do not exceed the maximum limit so that this building has fulfilled the requirements. The inter-level displacement due to earthquake loading does not exceed the limit so that this building is feasibly occupied. The performance level of the Alana Hotel is Immediate Occupancy (IO).
Optimum Structural Design of Self-Supported Shelter for Tsunami Evacuation in Padang City
Authors: Anas Ismail Febrin , Sunaryati Jati , Sahputra Deded Eka
Published: March 2020

A Self-Supported Shelter is a building that has an area about 100 m2 to 1000 m2 designated as a temporary vertical shelter for tsunami evacuation. The Self-Supported Shelter is built and managed by the community. That size of shelter is fit for mosques or mushollas (small Mosques) which is about 700 units spreading in the districts of Padang City. The Self-Supported Shelters are proposed since the number of vertical shelter is very limited at the moment. There are only four vertical shelters available in Padang City which are built by Government with capacity 2000-3000 people. Meanwhile, there is at least 600,000 people of Padang City must be evacuated in case of tsunami. There are four reasons for proposing the mosques or mushollas to be vertical shelters: First, that kind of building are available to small sub-district. Second, the land may be free to be developed. Third, they have an organization chosen by the community. Forth, it is easy to get construction funding for the religion reason. However, the community does not have guidance for developing a shelter for tsunami evacuation. This study is purposing to develop the optimum design of shelter in term of structural analysis. Here, the shelters are categorized into three types base on the area of the mosque or musholla: 10m x10m, 20m x20m and 30m x30m. Frame Structural Systems are used for the main structure of the building with or without the bracing system are involved. The optimum structural design is taken based on the strongest structure to restrain the applied loads. The soil-structure interaction analysis is also considered in to get a more reliable design. The results of the study may be used to guide the communities to build a proper shelter in their area
Bridge construction cost saving from using LRB (Lead Rubber Bearing) in the area prone to earthquake, Kenteng bridge case study
Authors: Dhanis Ariono , Arifin Herdianto , Zarkasi Iwan
Published: March 2020

There are many ways to reduce the earthquake force excited in the bridge structure, such as the use of Lead Rubber Bearing, Sliding Isolation Pendulum, and Damper/Lock Up Device. The concern that described in this paper is Lead Rubber Bearing support to damp earthquake thrust above the pier. The declared by the manufacturer guarantee is that the LRB can weaken the shock for about 30%. The analysis executed here is a response spectrum analysis calculating the natural frequency of the bridge. The contractual cost of the structure (with LRB structure) with the non-LRB structure were compared. We did not compare in terms of reinforced concrete volume reduction because the price of the LRB each and the price of the concrete with rebar per m3 are different. From the analysis, it is shown that without LRB, the price of the bridge will be increased at 19% from the original contractual price (before tax) or 16% saving. From this point, it is important to use LRB in our earthquake-prone area as the conclusion.
Seismic isolation system of two hinged arch suspended-deck bridge: a case study on Kalikuto bridge - Indonesia
Authors: Suryadi Tri , Delitriana Arvila , Fukar Zdenek , Tjendana Rusri
Published: March 2020

Seismic isolation systems are widely used in buildings, bridges, and industrial structures all over the world. The system is known for the efficiency to reduce earthquake demand and thus provide better seismic performance of the structures. In particular to application in an arch suspended-deck bridge, seismic isolation system can be a solution for the seismic resisting system due to the incapability of the cable hangers to transfer horizontal forces from excitation mass on the hanging deck to the main compression arches. Kalikuto arch bridge that is built in 2018 has implemented both Lead Rubber Bearings and Seismic Rubber Expansion Joints as the part of its seismic resisting system. These two seismic isolation devices were designed and engineered accurately to fulfil the seismic design requirements of the Kalikuto bridge. Finally, several performance tests were conducted to evaluate the design compliance of the manufactured devices.
A splitting subgradient algorithm for solving equilibrium problems involving the sum of two bifunctions and application to cournot-nash model
Authors: Duc Phung Minh , Le Xuan Thanh
Published: March 2020

In this paper we propose a splitting subgradient algorithm for solving equilibrium problems involving the sum of two bifunctions. At each iteration of the algorithm, two strongly convex subprograms are required to solve separately, one for each component bifunction. In contrast to the splitting algorithms previously proposed in Anh and Hai (Numer. Algorithms 76 (2017) 67–91) and Hai and Vinh (Rev. R. Acad. Cienc. Exactas Fis. Nat. Ser. A Mat. 111 (2017) 1051–1069), our algorithm is convergent for paramonotone and strongly pseudomonotone bifunctions without any Lipschitz type as well as Hölder continuity condition of the bifunctions involved. Furthermore, we show that the ergodic sequence defined by the algorithm iterates converges to a solution without paramonotonicity property. Some numerical experiments on differentiated Cournot-Nash models are presented to show the behavior of our proposed algorithm with and without ergodic.
Comments on: Confirming geomagnetic Sfe by means of a solar flare detector based on GNSS
Authors: Hernández-Pajares Manuel , García-Rigo Alberto
Published: March 2020

We report two comments affecting the paper “Curto JJ, Juan JM & Timoté CC, 2019. Confirming geomagnetic Sfe by means of a solar flare detector based on GNSS. J Space Weather Space Clim 9: A42. https://doi.org/10.1051/swsc/2019040”: The first comment is the reporting of two mistakes which distorts the central model used for the measurement and detection of solar flares with GNSS, that might affect as well the most part of results and discussions contained in the paper. And the second comment is the clarification about the authors’ claim of presenting the first work of using the electron content enhancement estimation at the subsolar point for characterizing solar flares with GNSS data, which is not accurate due to the existence of such previous definition and usage.
Antibiotic Stewardship bei ambulant erworbener Pneumonie
Authors: Leo Fabian , Stegemann Miriam Songa , Maurer Florian
Published: March 2020

Antibiotic stewardship (ABS) denotes structured and continuous measures to improve the quality of prescribing anti-infectives. The aim is to achieve optimal treatment results and to minimize undesirable effects, especially the emergence of antibiotic resistance. This review summarizes the most important ABS principles based on recently published studies with implications for the management of community-acquired pneumonia. Local guidelines, education and training and “prospective audit and feedback” are established strategies to improve the management of patients with community-acquired pneumonia. However, the implementation of ABS programs requires trained personnel and may be impeded by limited structural and time resources. Hence, electronic health records and computer-based interventions are useful support for ABS programs and offer potential to facilitate ABS in inpatient and outpatient care. PCR-based rapid diagnostic tests, PCT-guided algorithms and penicillin allergy testing are suitable procedures to supplement ABS programs.
Custom-made Gold Implant for Management of Lagophthalmos: A Case Report
Authors: Tuna Suleyman Hakan , Gumus Hasan Onder , Hersek Nur
Published: March 2020

Lagophthalmos is defined as the inability to close the eyelids completely. This situation may
lead to corneal problems such as epithelial defects, stromal thinning, exposure keratitis, bacterial
infection, perforation, and blindness. A patient with lagophthalmos underwent insertion of a custommade gold weight implant. After implantation, the patient was able to close her eye and expressed high cosmetic and aesthetic results. Fabrication of gold weight implant by the means of a rolling machine is an effective and easy way and should be considered in the management of lagophthalmos. (Eur J Dent 2008;2:294-298)
Surgical, Orthodontic and Prosthodontic Rehabilitation of a Patient with Follicular Ameloblastoma: A Case Report
Authors: Sailer Herman F. , Tarawneh Fadi , Fourkas Panagiotis , Antoniades Dimitrios Z. , Athanasiou Athanasios E.
Published: March 2020

This case report describes the combined surgical, orthodontic and prosthodontic rehabilitation of an adult female patient with a previous history of follicular ameloblastoma, which was treated through partial mandibulectomy and an immediate replacement of missing bone with an autologous calvarial bone graft. Orthodontic treatment was undertaken in order to restore occlusal disturbances and obtain sufficient space for two dental implants and an optimum prosthodontic rehabilitation. (Eur J Dent 2010;4:192-196)
Functional Treatment of an Asymmetry Case Having Left Side Paralysis: A Case Report
Authors: Rubenduz Meliha , Uslu Ozge
Published: March 2020

This case report presents the results of functional and myofunctional treatment of a 9-year, 5-month-old male patient with laterognathy, facial asymmetry and dentofacial deformity. The patient had a history of herpes encephalitis at age 8.5 months and palsy on the left side in early childhood, and his left side remained paralyzed as a sequela. The patient had dentoalveolar asymmetry with a Class I right and Class III left canine relation, a 1.5 mm midline deviation, anterior cross-bite, an overjet of -3 mm and an overbite of 3 mm. The dentoalveolar and facial asymmetries were corrected using a modified removable appliance, with an acrylic vestibular shield inserted on the right side to guide the mandible in the upper arch and an acrylic plate with artificial teeth in the lower arch. The patient was instructed to practice myofunctional exercises regularly. In total, treatment, including observation, was completed in a period of 2 years and 10 months, at which time, a marked correction in facial asymmetry and profile and improvement in smile esthetics could be observed. (Eur J Dent 2010;4:341-347)
Nasal Prosthesis Rehabilitation after Partial Rhinectomy: A Clinical Report
Authors: Seçilmiş Aslı , Öztürk A. Nilgün
Published: March 2020

Facial defects resulting from neoplasms, congenital malformations, or trauma can be restorated with facial prostheses using different materials and retention methods to achieve a lifelike look and function. For the successful result, a lot of factors as harmony, texture, color matching, and blending of tissue interface of prosthesis is important. This clinical report describes treatment using a silicone prosthesis with a mechanical - retentined design for a patient who received a partial rhinectomy. Defects resulting from diseases as squamous cell carcinoma can be managed with the prosthetic rehabilitation so that the patient more comfortably and confidently resumed regular daily activity. Mechanical retention alone was sufficient to retain the prosthesis; thus, prosthetic adhesives were not necessary. (Eur J Dent 2007;2:115-118)
An Alternative Approach to Combine Orbital Prosthesis and Obturator: A Case Report
Authors: Soganci Gokce , Yalug Suat , Kocacikli Mustafa
Published: March 2020

This report describes a different approach for diminishing the movements of orbital prosthesis during mimic movements and chewing function. Mechanical devices such as magnets are used to enhance the retention in case lack of the implants. However rigid fixation of obturator and orbital prosthesis can result in movements of the orbital prosthesis during mastication. In this case obturator and orbital prosthesis are combined by magnets. However this combination is not rigid because of an active part which provides movement. This active part allows movements in a space constructed in the acrylic base of orbital prosthesis. Thus, the movements that may occur on orbital prosthesis during chewing can be diminished by this simple mechanism. Due to the fact that designing such a mechanism that minimizes the movements of the orbital prosthesis contributes patient’s comfort. (Eur J Dent 2011;5:459-464)
Five Years of Practical Experience Using the Revised Proving Guidelines of the Homœopathic Pharmacopœia Convention of the United States
Authors: Hoover Todd A.
Published: March 2020

The Homœopathic Pharmacopœia of the United States (HPUS) is one of the three officially recognized compendia of medical drugs in the United States. A well-conducted homeopathic proving is one pathway to entry into the HPUS. In 2013, guidelines for homeopathic drug provings were updated to better assess the methodology of provings and improve the confidence in the outcomes generated. In addition, the team who developed the revised guidelines included a pragmatic approach to assess the quality of proving outcomes in terms of their usefulness in determining the therapeutic profile. The monograph review team, composed of homeopathic clinicians and researchers, has evaluated 25 new homeopathic medicines for monograph purposes. The team has noted that the guidelines have helped frame and standardize the monograph review process. The revised structure for monograph reporting has enhanced the reviewer's ability to ascertain the therapeutic profile for a new substance. Sponsors have stated that the new guidelines have helped increase their conformance with Good Clinical Practices, helped improve the reporting and transparency of their provings, and may help safeguard provings as a valid research method. Similar harmonized guidelines have been adopted by the European Committee for Homeopathy and the Liga Medicorum Homœopathica Internationalis.
Management of Dorsal Graft and Implant Infections
Authors: Chen David S. , Wang Tom D.
Published: March 2020

Deficiency of the nasal dorsum can result from several etiologies, most commonly congenital, traumatic, or iatrogenic. The use of dorsal grafts or implants for augmentation of the dorsum is a mainstay of both functional and cosmetic rhinoplasty. Due to the cosmetically sensitive nature of the dorsum, and the relatively large amount of graft or implant material that is typically used, infections in this area can be particularly difficulty to manage. Here, we review the current literature on dorsal graft and implant infections, along with options for management.
A Nationwide Analysis of Early and Late Readmissions following Free Tissue Transfer for Breast Reconstruction
Authors: Magno-Padron David Alejandro , Collier Willem , Kim Jaewhan , Agarwal Jayant P. , Kwok Alvin C.
Published: March 2020

Background Traditionally, surgical quality outcomes are assessed using a 30-day postoperative window. For breast cancer patients undergoing free tissue transfer for breast reconstruction, we sought to describe the distribution of and specific risk factors for early and late readmissions within a 0- to 90-day postoperative period.

Patients and Methods The Nationwide Readmissions Database was used to conduct a retrospective cohort study. Breast cancer patients undergoing free tissue transfer for breast reconstruction were identified using International Classification of Diseases -9 diagnosis and procedure codes. Ninety-day readmissions related to infection or wound complications were identified. Univariable and multivariable logistic regression models were used to identify patient risk factors for readmissions that occurred early (0–30 days) and late (31–90 days) after their index procedure.

Results In the weighted sample, we identified approximately 7,305 free flap breast reconstructions and a surgical wound-related readmission rate of 4.3% (n = 312): 65.4% of the readmissions occurred early while 34.6% occurred late after surgery. The mean days to readmission was 26, and 75% of all readmissions occurred within the first 36 days after surgery. Variables independently associated with readmissions during the 0- to 90-day postoperative period included: history of chronic obstructive pulmonary disease (p = 0.036), hypertension (p = 0.03), obesity (p ≤ 0.001), and history of smoking (p = 0.004). The variables independently associated with the early readmission period were the same as those identified for the 0- to 90-day postoperative period. The variables independently associated with late readmissions were different: history of depression (p = 0.001) and history of smoking (p = 0.001).

Conclusion The conventional 30-day hospital readmission rate classically used as a quality metric is overlooking a significant portion of admissions after free flap-based breast reconstruction. Different variables were found to be associated with readmission in the early versus late cohorts. Interventions targeting these variables could decrease readmissions and their associated costs.
Aicardi–Goutières Syndrome Type 2: A Report on Two Cases with Different Phenotypes Caused by RNASEH2B Gene Mutations
Authors: Portale Anna , Mazzurco Marina , Portale Laura , Pavone Piero , Bertini Enrico , Polizzi Agata , Praticò Andrea D. , Ruggieri Martino
Published: March 2020

Aicardi–Goutières syndrome (AGS) is a rare disorder characterized by acquired microcephaly, cerebral calcifications, leukodystrophy, cerebral atrophy, chronic lymphocytosis, and increased interferon-α in cerebrospinal fluid. We report on two children affected by AGS type 2, caused by mutations in RNASEH2B. The first child had the mutation c.529G > A (p.A177T) and presented with an atypical and mild phenotype, with delayed psychomotor development, calcifications of the brain white matter and basal ganglia, and interferon signature positivity. The disease course was stable. The second child presented the mutation c.554T > G (p.V185G) and showed a later onset (15 months) and a more progressive clinical course with functional inability in the upper limbs, steppage gait, and irritability. Despite immunoglobulin therapy, she developed to progressive tetraparesis and severe hypotonia. This case report highlights that RNASEH2B mutation cannot fully predict the phenotype of AGS type 2 when a mutation c.529G > A occurs. Moreover, an earlier symptomatology may be not related to a more severe prognosis or to a partial or absent response to treatment.
Changes to Venous Flow Coupler Signal during DIEP Flap Inset Can Be Predictive of Poor Clinical Outcomes in Autologous Breast Reconstruction
Authors: Colakoglu Salih , Johnson Ariel , Anderson Jaclyn , Mathes David Woodbridge , Chong Tae Woon
Published: March 2020

Background Venous flow couplers are typically used to monitor free flaps during the postoperative period, with a continuous venous signal available immediately after completion of the anastomosis. Intraoperative loss of the coupler signal is not uncommon and may require adjustments in free flap inset and even flap thickness to get the venous signal to return. The effects of intraoperative coupler signal loss and the role of this technology on flap outcomes have not been evaluated. We hypothesized that the use of intraoperative coupler can be protective of both early and late flap complications by preventing unfavorable flap insets.

Patients and Methods All patients who underwent free flap breast reconstruction between January 2018 and June 2019 by single microsurgery team were included. Flap inset and inset changes based on flow coupler signal problems were reviewed in the procedure notes. Patient demographics data and clinical outcomes were analyzed with comprehensive chart review.

Results Forty-four consecutive patients with 69 free flaps were identified. There were no significant differences in patient characteristics or venous coupler size used in venous anastomosis. Although the number of operating room take backs for venous insufficiency was not significantly different between two groups, the free flaps with inset change had significantly higher complications that required later surgical intervention (p = 0.0464).

Conclusion Surgeons should be aware that intraoperative coupler signal loss can be associated with poor clinical outcomes postoperatively and these flaps may require more perfusion imaging, flap debulking, or even additional venous anastomosis.
Rasmussen Encephalitis: An Update
Authors: Cay-Martinez Karla C. , Hickman Richard A. , McKhann II Guy M. , Provenzano Frank A. , Sands Tristan T.
Published: March 2020

Rasmussen encephalitis (RE) is a rare, devastating, progressive pediatric epilepsy. First described 60 years ago, RE continues to present challenges in diagnosis and management. RE causes a unilateral focal epilepsy in children that typically becomes medically refractory, results in significant hemiparesis, and causes progressive cognitive decline. The etiology is a cell-mediated immune attack on one cerebral hemisphere, though the inciting antigen remains unknown. While the underlying histopathology is unilateral and RE is described as “unihemispheric,” studies have demonstrated (1) atrophy of the unaffected hemisphere, (2) electroencephalographic abnormalities (slowing and spikes) in the unaffected hemisphere, and (3) cognitive decline referable to the unaffected hemisphere. These secondary contralateral effects likely reflect the impact of uncontrolled epileptic activity (i.e., epileptic encephalopathy). Hemispheric disconnection (HD) renders 70 to 80% of patients seizure free. While it has the potential to limit the influence of seizures and abnormal electrical activity emanating from the pathological hemisphere, HD entails hemiparesis and hemianopia, as well as aphasia for patients with dominant HD. With the recent expansion of available immunomodulatory therapies, there has been interest in identifying an alternative to HD, though evidence for disease modification is limited to date. We review what is known and what remains unknown about RE.
Development of a real-time algorithm for detection of the divertor detachment
radiation front using multi-spectral imaging
Authors: Ravensbergen T. , van Berkel M. , Silburn S.A. , Harrison J.R. , Perek A. , Verhaegh K. , Vijvers W.A.J. , Theiler C. , Kirk A. , de Baar M.R. , the EUROfusion MST1 team
Published: March 2020

In this paper we present a novel algorithm to extract the optical plasma boundary and
radiation front for detached divertor plasmas. We show that reliable detection of the divertor
leg and radiation front is possible using lightweight image processing tools. Using a
non-tomographic approach, the detected divertor leg and radiation front can be mapped to the
poloidal plane. This approach is fast and accurate enough for real-time control purposes,
allowing in particular real-time plasma shape and detachment control, and post-shot detachment
physics and dynamics analysis.
HOTS Android-Based student worksheets to practice creative thinking ability of vocational school students
Authors: Prastyo A B , Gembong S , Masfingatin T , Maharani S
Published: March 2020

This study aims to describe the development of an Android-based HOTS Student Worksheet to train the creative thinking skills of vocational students. The type of research used is Research and Development (R & D) using the ADDIE model which consists of five stages: 1) analyze, 2) design, 3) development, 4) implementation, and 5) evaluation. The research subjects were class XI students in Online and Marketing Business (BDP) majoring in SMK Negeri 1 SekarBojonegoro, totaling 33 students. The research instruments used were learning media validation sheets, test questions, and student response questionnaires. The results of this study are HOTS-based Android LKS learning media that meet very valid criteria with an average of 90.22%, practically with an average student response questionnaire of 80.30% and effective to train creative thinking skills of class XI students of linear program material.
The colour Lego media for mathematics in elementary school
Authors: Rohmatin T , Wulan B R S , Syakur A , Wina T
Published: March 2020

This study aims to determine the increase in student mathematics learning outcomes in integer addition material. The subjects of this study were students at SDN Bluru Kidul 2 Sidoarjo. This research used class action research design. Data collecting technique that use it, they are observation and test. Data that have collected will be analyzed by using descriptive quantitative analysis technique. Research result showed that by applying color LEGO media it increased student learning result with classical completeness that obtained on first cycle as big as 64%, second cycle as big as 88%. Beside it, from the research result it also show that there is an improvement on teacher activity on first cycle with percentage as big as 71,15% and on second cycle 95,19%, also improvement on student activity on first cycle with percentage as big as 71,59% and second cycle with percentage 94,89%. Because of that, It was concluded that teaching material of totaling number can be taught by using increase Lego color media.
The Effect of Coral Reef Comic Media Implementation on Students’ Environmental Care Attitude in Indonesia
Authors: Sukri A , Efendi I , Hastuti R , Ramdani A , Lukitasari M
Published: March 2020

The purpose of this study was to analyze students’ environmental care attitudes towards coral reef ecosystems through the implementation of coral reef comic media in West Nusa Tenggara. This research was a quasi-experimental study that adopted and modified separate sample pretest-postest designs. Two pilot schools originating from Sumbawa Regency, namely SMAN 1 Alas and SMA Muhammadiyah Alas were randomly selected with a total of 50 students. Attitudes of students’ environmental care is collected through a questionnaire. Scores on the questionnaire were then converted into percentages then analyzed by using paired sample t test to see differences in students’ attitudes before and after treatment at each school, and independent sample t-test to see differences in student attitudes between observational schools. The results showed that (1) there were differences in the attitudes of students before and after being treated using the coral reef comics media in each observation school (p <.05), and (2) there were differences in the attitudes of students’ environmental care between the two observation schools (p <.05). Based on the results of the study it can be concluded that (1) the implementation of coral reef comic media can increase students’ positive attitudes about the environment especially the coral reef ecosystem, (2) students at schools that are geographically close to the coast tend to have a higher caring attitude than students at schools whose geographical location is far from the coast.
Traffic Light Regulatory System Based on Fuzzy Algorithm Using Microcontroller
Authors: Latif Abdul , Megantoro Prisma
Published: March 2020

Basically, control system for traffic lights only perform control based on a fixed time. In fact, the arrival rate of vehicles at the intersection of the road is not always the same so of course congestion at the crossroads can not be controlled. This study presents a simulation control system which can perform automatic traffic light control based on vehicle arrival rate. In this control, the duration of the flame is not constant but follows the arrival rate of vehicles. The method used to control the flame duration is fuzzy logic algorithm with the Mamdani fuzzy reasoning using Matlab software. Test results based on the simulation of fuzzy logic in fuzzy MatLab toolbox show that the fuzzy logic algorithm can be used to meet the goal of optimal traffic control, the duration of a given time based on the arrival rate of vehicles. The higher rate of arrival of the vehicle, the longer the duration of a given time, and the lower rate of the arrival of the vehicle, the more briefly given time duration.
Effect of Postharvest Maturation Storage at Different Age Fruit on Chemical Characters Fruit and Seed of Wood-apple (Feronia limonia (L.) Swingle)
Authors: Murrinie Endang Dewi , Yudono Prapto , Purwantoro Azis , Sulistyaningsih Endang
Published: March 2020

Wood-apple fruits generally processed and consumed are those of fallen mature fruits which are then stored in postharvest ripening for 3 to 6 days. Seeds are obtained from the waste of processed wood-apple fruits. The seeds are not directly extracted but they had experienced a postharvest maturation storage prior to planting. During postharvest maturation storage, there are changes in the chemical characteristics of wood-apple fruit flesh and seeds. The research objective was to determine the effect of postharvest maturation storage on the different fruit ages on the chemical character of fruit and seed of wood-apples. The results showed that postharvest maturation storage did not affect the total sugar content of the fruit, but it affected the content of tannins and phenols, meanwhile fruit age affected the total sugar content, tannin and phenol fruit. Postharvest maturation storage did not affect the dry weight, moisture content and protein content of the seed, but it affected electrical conductivity and respiration rate of seeds. Meanwhile fruit age affected the dry weight, moisture content, protein content, electrical conductivity and the respiration rate of seeds.