bluuebunny/crossref_metadata_2025 huggingface dataset:
ОЧІКУВАННЯ ВІД РІШЕННЯ СУДУ ЯК ВИД МАЙНОВОГО ОЧІКУВАННЯ В ЦИВІЛЬНОМУ ПРАВІ
Authors: Луценко Дмитро Сергійович
Published: August 2024

Очікування від рішення суду як вид майнового очікування в цивільному праві є складним і багатогранним явищем, яке потребує детального аналізу та дослідження. Це поняття охоплює різні аспекти правової теорії та практики, включаючи правову природу, критерії визнання, правові наслідки та механізми захисту майнових очікувань. Ця стаття розкриває ключові аспекти цього питання, включаючи визначення майнових очікувань, їх класифікацію та роль у цивільному процесі. Майнові очікування від рішення суду можна визначити як законні надії сторін на отримання певного майнового результату від судового процесу. Ці очікування виникають на підставі правових норм та фактів, що обґрунтовують претензії сторін, і вони можуть мати значні економічні та правові наслідки. Правова природа майнових очікувань залишається предметом дискусій у юридичній науці. Деякі дослідники розглядають їх як суб'єктивні права, що підлягають захисту, тоді як інші вважають їх лише правовими очікуваннями, які не створюють самостійних прав. Визначення правової природи майнових очікувань є ключовим для розуміння їх правового статусу та можливостей захисту. Критерії визнання майнових очікувань від рішення суду включають наявність законних підстав для очікувань, обґрунтованість претензій та наявність реальних шансів на отримання бажаного результату. Судова практика відіграє важливу роль у визначенні цих критеріїв, формуючи прецеденти та правові позиції, які впливають на стабільність правової системи. Наприклад, у справах про спадкування, очікування на отримання спадкового майна може бути визнане майновим очікуванням, якщо воно базується на законних підставах, таких як заповіт чи рішення суду про визнання спадкоємця. Правові наслідки визнання майнових очікувань можуть бути різноманітними. Вони можуть включати компенсацію за втрату очікуваних вигод, захист від неправомірних дій інших сторін та забезпечення виконання судових рішень. Захист майнових очікувань є важливим аспектом цивільного права. Сторони можуть звертатися до суду з метою захисту своїх очікувань, використовуючи різні правові механізми, такі як позови про визнання права, відшкодування збитків, накладення арешту на майно тощо. Ефективний захист майнових очікувань вимагає вдосконалення законодавства та правозастосовної практики. Практичні аспекти реалізації прав на майнові очікування включають вирішення конкретних спорів, застосування правових норм та забезпечення справедливого судочинства. На практиці виникають численні проблеми, такі як правова невизначеність, складність доказування та конфлікти інтересів. Вирішення цих проблем є важливим завданням для забезпечення стабільності та передбачуваності правових відносин. Узагальнюючи, майнові очікування від рішення суду є важливим елементом цивільного права, що вимагає глибокого наукового дослідження та розробки ефективних правових механізмів для їх захисту. Це сприятиме підвищенню правової культури, захисту прав та інтересів учасників судових процесів та зміцненню правової системи в цілому.
РЕФОРМА КОРПОРАТИВНОГО УПРАВЛІННЯ В УКРАЇНІ ТА ФІДУЦІАРНІ ОБОВ'ЯЗКИ: ПОДВІЙНА ЮРИДИЧНА ПРИРОДА ОБОВ'ЯЗКУ ДБАЙЛИВОСТІ
Authors: Трубаков Євген Олександрович
Published: August 2024

З прийняттям Європейським парламентом та Радою плану Ukraine Facility 2024-2027 почався якісно новий етап реформ, спрямованих на уніфікацію законодавства України і Європейського союзу. Однією з головних реформ, в рамках названого плану, є реформа корпоративного управління державними активами. Результатами її проведення є внесення змін у низку законодавчих актів, зокрема і до Цивільного кодексу України, в якому вперше з’явилося законодавче визначення фідуціарних обов’язків лояльності і дбайливості. Реформа корпоративного управління виходить за межі державного сектору економіки, адже легальне визначення фідуціарних обов’язків посадових осіб виконавчого органу та наглядової ради поширює свою дію також і на юридичних осіб приватного права. Метою вказаної реформи є наближення українського законодавства до відповідних практик ОЕСР. Саме тому аналіз змісту фідуціарного обов'язку дбайливості був проведений за допомогою такого інструменту м’якого права як Принципи корпоративного управління G20/ОЕСР 2023. Із результатів проведеного дослідження вбачається, що обов’язок дбайливості має подвійну правову природу: це, з однієї сторони, набір формальних вимог до якісного управлінського рішення, а з іншої – правило, яке звільняє посадових осіб від відповідальності за завдані юридичній особі збитки, якщо управлінське рішення було прийнято поінформовано, добросовісно та без конфлікту інтересів. Таке правило в американській юридичній доктрині відомо як правило ділового судження, яке в різних формах існує у всіх країнах, які імплементують кращі практики корпоративного управління. Незважаючи на те, що правило ділового судження є невід’ємною частиною обов’язку дбайливості, воно не було закріплено у легальному визначенні фідуціарних обов’язків. Окрім виправлення цього недоліку, видається, що наступним етапом запровадження кращих практик корпоративного управління в Україні стане правотворча діяльність, спрямована на встановлення базового стандарту перевірки дій посадових осіб, а також визначення меж втручання суду у дискрецію посадових осіб при перевірці виконання останніми їх фідуціарних обов’язків.
ОСНОВОПОЛОЖНІ ІДЕЇ (ПРИНЦИПИ) АДМІНІСТРАТИВНО-ПРАВОВОГО ЗАБЕЗПЕЧЕННЯ ПРОДОВОЛЬЧОЇ БЕЗПЕКИ
Authors: Пустовіт Юлія Юріївна
Published: August 2024

У статті розглянуто проблемні питання сутності дефініцій «принципи», «принципи адміністративного права» та «принцип адміністративно-правового забезпечення продовольчої безпеки», проаналізовано сучасні погляди дослідників щодо вивчення принципів загалом і у конкретній сфері відповідно, їхньої ідентифікації в системі адміністративно-правового забезпечення продовольчої безпеки (за його складовими, видами та формами). Встановлено, що поняття «принципи адміністративного права» та «принцип адміністративно-правового забезпечення продовольчої безпеки» є видовим поняттями від родового поняття «принцип права» та основного поняття «принцип», що проявляється через зіставлення їхніх ознак. Визначено, що поняття «принцип адміністративно-правового забезпечення продовольчої безпеки» з притаманною йому сукупністю всіх ознак є способом трансформації основних принципів права. Проаналізовано нормативно-правові акти сфери продовольчої безпеки, зокрема, Римська декларація з всесвітньої продовольчої безпеки. Виокремлено принципи у сфері адміністративно-правового забезпечення продовольчої безпеки. Встановлено, що недоліком у законодавстві України з питань адміністративно-правового забезпечення продовольчої безпеки є недостатня узгодженість існуючих принципів, які закріплені у різних нормативно-правових актах, а також недостатність виявлення (виокремлення) науковцями нових принципів, які з’являються у зв’язку з інтеграцією у європейське середовище України та їхнього закріплення на законодавчому рівні. Підтверджено, що принципи адміністративно-правового забезпечення продовольчої безпеки – це науково обґрунтовані основні засади, вихідні положення, які визначають особливості виникнення, розвитку та функціонування інституту адміністративно-правового забезпечення продовольчої безпеки, є базою для розвитку науки адміністративного права у складі з інститутами, втілюють у собі цінності, що визначають правосвідомість та правову поведінку суб’єктів адміністративних відносин, а саме: адміністративно-правового забезпечення продовольчої безпеки.
ОСОБЛИВОСТІ ПЛАНУВАННЯ ПРАВОТВОРЧОЇ ДІЯЛЬНОСТІ В ПОВОЄННИЙ ПЕРІОД
Authors: Гусар Ольга Анатоліївна
Published: August 2024

У статті здійснено аналіз останніх наукових досліджень присвячених правотворчій діяльності, з чого слідує що ця тема є актуальною серед науковців, які всебічно її досліджують, здійснюючи глибоку аналітичну роботу. Відзначено важливість прийняття Закону про «Правотворчу діяльність», який унормував формат здійснення такої діяльності. В роботі приділено увагу особливостям правотворчої діяльності у воєнний та повоєнний період відновлення українського законодавства та визначено, що така діяльність спрямована на планування та видання нормативно-правових актів надзвичайного характеру, які закладають основи забезпечення безпеки, захисту прав людини і громадянина та обов’язково враховують міжнародно-правові зобов’язання України, напрямки, пріоритети та цілі, що визначені програмними документами. Визначено, що в повоєнний період вектор правотворчої діяльності спрямовано на відновлення зруйнованої інфраструктури, запровадження компенсаторних заходів учасникам бойових дій, на соціальне забезпечення населення, залучення інвестицій, ефективний судовий захист та інше. Обґрунтовано, що планування правотворчої діяльності є безперервний, узгоджений процес підготовки та прийняття (видання) нормативно-правових актів, з метою забезпечення прогнозованого розвитку публічної політики, який здійснюється шляхом прийняття документів та перспективного планування суб’єктами правотворчої діяльності, враховуючи результати науково-експертних висновків, фахових експертиз щодо визначення основних орієнтирів, засад, принципів, вдосконалення галузевого законодавства, встановлення пріоритетності та послідовності прийняття законодавчих актів.
ДОКТРИНА ПРАВОТВОРЧОСТІ ЯК ОКРЕМИЙ ЕЛЕМЕНТ СИСТЕМИ ПРАВА
Authors: Мельник Ярослав Ярославович
Published: August 2024

Статтю присвячено дослідженню проблем правотворчості у призмі правової доктрини та елементів системи права. У статті розглядається система права та розкриваються основні тенденції розвитку правової доктрини, аналізується чинне законодавство та судова практика. У статті досліджуються творчість, як категорія філософії, досліджується питання регрес, як філософської категорії, обґрунтовується правотворчість як феномен права та визначається його місце в системі права та доктрині правотворчості; аналізується доктринальне значення системи права та її елементів; розкриваються особливості правової доктрини, – в результаті чого ставиться питання про виокремлення доктрини правотворчості, як окремого елементу системи права. А саме тому, що така заснована на правових вченнях, дослідженнях, наукових розробках та «наукових звичаях» (постулатах). Вона (доктрина правотворчості) охоплюється правозастосовною діяльністю згідно до Закону № 3354-IX від 24 серпня 2023р. За результатами дослідження робляться висновки стосовно, які полягають у визначення поняття «доктрини правотворчості», визначено ознаки правотворчості та елементи доктрини правотворчості як системи права. Пояснюється їх суть та розкривається їх зміст. Зокрема, встановлено такі ознаки доктрини правотворчості як от: «методологічна-інструментальна ознака»; «ознака засновництва»; «ознака наукового планування»; «ознака наукової передбачуваності», «ознака системності». На системному рівні (співвіднесення до системи права), встановлено, що доктрині правотворчості притаманні такі елементи як от елемент (1)системного утворення, який засновується на: (а)цілісності; (б)узгодженості; (в)внутрішній структурованості (організованості); (2)наявність соціальної обумовленості; (3)відображення статики та динаміки доктрини правотворчості; (4)групування елементів системи права завдяки доктрині правотворчості; (5)можливість відображати внутрішню будову права у доктринальному змісті.
Inteligência artificial, vieses algorítmicos e racismo: o lado obscuro da justiça algorítmica
Authors: Chaves Junior Airto , Guasque Bárbara , Aguiar de Pádua Thiago
Published: August 2024

This article aims to identify some negative externalities arising from non-observance of certain ethical standards in AI models. The study aims to clarify the importance of paying close attention to the database that are used in the construction of AI models, as well as listing possible solutions to reduce the incidence of biased algorithms and mitigate their harmful consequences. The justification for the scope of the work lies in the need to know the perverse effects that biased algorithms can produce in the justice system and in society in general, violating fundamental rights and catalyzing prejudices and segregations inherent to the society on which they are based. The inductive method is employed in the research phase and production of the research report; in the processing of the data, the Cartesian method is used; for verification of the results, it uses the inductive logic. As for the methodology, the exploratory and descriptive nature is used.
Plasmonic Enhanced Nickel Catalysed Coupling of Aliphatic Alcohol
Authors:   , Liu Henry
Published: August 2024

The projects propose a new gold-nickel alloy photocatalyst system for the Guerbet reaction under mild reaction condition. The introduction of small ratio of gold significantly increases the reaction rate. Gold as the antenna absorbs light energy and produces hot electrons. The hot electrons can promote the homo-coupling process of aliphatic alcohol under light irradiation. This decreases the temperature required for the homo-coupling of alcohol and no harmful side product, which saves energy and conforms with the concept of green chemistry.
Driving the Intention Cue Motorway: Merging Ethnographic Enquiries and Machine Learning Techniques for Decoding Context-Dependent Intention Awareness in Driving
Authors:   , Pardo Gaytan Jorge Luis
Published: August 2024

This research explored how passengers perceive drivers' intentions in naturalistic driving, aiming to improve human interaction with automated vehicles. It identified key non-verbal cues that convey driving intentions by combining human-centric methods and AI techniques. The project created a unique dataset of intention cues and developed a machine learning model to study passengers' intention awareness. This model was enhanced with explainable AI to highlight influential factors. This pioneering work demonstrates how AI can extract meaningful patterns from sensor data and ethnographic observations in real-world driving scenarios. The findings may inform future automated vehicle interface design, potentially improving predictability and trust.
Analysis of Crash Frequency Data Considering Simultaneously Multiple Objectives and Advanced Modelling Aspects
Authors:   , Ahern Zeke
Published: August 2024

Crash prediction models are vital for road safety, aiming to understand and mitigate crash factors. Developing these models involves extensive hypothesis testing, which affects results and interpretations. Analysts often face challenges such as restricted model specifications that may omit key factors, leading to biases and misspecification. This research introduces a framework to estimate crash prediction models by integrating diverse modelling considerations, such as potential contributing factors, functional forms, and heterogeneous effects, within a systematic testing environment. It utilizes an optimization-based search strategy to explore these factors efficiently while maintaining interpretability.
Unilateral Plyometric Jump Training Shows Significantly More Effective than Bilateral Training in Improving Both Time to Stabilization and Peak Landing Force in Single-Leg Lend and Hold Test: A Randomized Multi-Arm Study Conducted Among Young Male Basketball Players
Authors: Zhao YongXing , Sun MingMing , Wang XiaoShuang , Xu Qi
Published: August 2024

Enhancing peak landing forces and ensuring faster stabilization in the lower limbs during jumping activities can significantly improve performance and decrease the risk of injury among basketball players. This study aimed to compare the effects of unilateral (uPJT) and bilateral plyometric jump training (bPJT) programs on various performance measures, including countermovement jump (CMJ), squat jump (SJ), and single-leg land and hold (SLLH) test outcomes, assessed using force plates. A randomized multi-arm study design was employed, comprising two experimental groups (n = 25; uPJT and n = 25; bPJT) and one control group (n = 25), conducted with youth male regional-level basketball players (16.3 ± 0.6 years old). Participants underwent assessment twice, both before and after an 8-week intervention training period. The uPJT program exclusively involved plyometric drills (e.g., vertical jump exercises; horizontal jump exercises) focusing on single-leg exercises, whereas the bPJT program utilized drills involving both legs simultaneously. The outcomes analyzed included CMJ peak landing force, CMJ peak power, SJ peak force, SJ maximum negative displacement, SLLH time to stabilization, and SLLH peak landing force. The control group exhibited significantly greater SLLH time to stabilization compared to both the uPJT (p < 0.001) and bPJT (p < 0.030) groups. Additionally, time to stabilization was also significantly higher in bPJT than in uPJT (p = 0.042). Comparisons between groups in regards SLLH peak landing force after intervention revealed that the value was significantly smaller in uPJT than in bPJT (p = 0.043) and control (p < 0.001). In the remaining outcomes of CMJ and SJ, both uPJT and bPJT showed significant improvement compared to the control group (p > 0.05), although there was no significant difference between them. In conclusion, our study suggests that utilizing uPJT is equally effective as bPJT in enhancing performance in bilateral jump tests. However, it significantly outperforms bPJT in improving time to stabilization and peak landing forces during single-leg land and hold test. uPJT could be advantageous not for maximizing performance but also for potentially decreasing injury risk by enhancing control and balance during single-leg actions, which are common in basketball.
A relational approach to digital racism: Toward a theoretical model
Authors: Ekman Mattias
Published: August 2024

In recent decades, anti-immigrant, racist and nationalist attitudes have become increasingly mainstream, transforming public debates on immigration and immigrants in Europe and beyond. These attitudes and sentiments have been widely disseminated and amplified through digital communication, including commercial social media platforms. To better understand the relationship between racism and digital communication, it is necessary to move beyond media-centric explanations and simplified discussions of online hate speech and platform regulation. Therefore, this paper proposes a multi-theoretical approach to digital racism, i.e., racist content produced and circulated online. The paper presents an understanding of digital racism in relation to four perspectives: networked affect, nationalism, masculinity and conspiracy thinking. It takes a relational approach to these theoretical perspectives and discusses how they could be utilized to understand and analytically approach digital racism at the macro, meso and micro levels.
Digital battleground: An examination of anti-refugee discourse on Twitter against Ukrainians displaced by Russia’s invasion of Ukraine
Authors: Gruzd Anatoliy , Mai Philip , Taleb Omar
Published: August 2024

Russia’s war of aggression in Ukraine has triggered Europe’s largest refugee crisis since World War II. In this case study, we investigate the prevalence and types of anti-refugee discourse about Ukrainian refugees on Twitter. Previous studies primarily focused on public discourse and attitudes toward racialized refugees and immigrants; the Ukrainian refugee crisis is unique in that it is one of the few instances of a recent refugee crisis involving people who do not come from mostly racialized communities. Using Communalytic, a computational social science tool for studying public discourse on social media, we automatically collected and identified toxic posts mentioning Ukrainian refugees during the first year of Russia’s full-scale invasion of Ukraine. We focused on posts containing toxic language, as this is where we are most likely to find examples of anti-refugee sentiments. Based on a manual analysis of 2,045 toxic posts referencing Ukrainian refugees, the most prevalent ones were politically motivated and included partisan content (33 percent), followed by posts containing expressions countering anti-refugee narratives (20 percent). These findings highlight the escalating politicization and polarization of discussions about Ukrainian refugees both online and offline. Furthermore, 53 percent of the sample aligned with pro-Kremlin narratives against Ukraine. By exploiting anti-refugee sentiments and leveraging existing political and cultural fault lines in the West, pro-Kremlin messages on Twitter contribute to diminishing support for Ukrainian refugees, minimizing the severity of the war, and undermining international support for Ukraine.
Potential of purple eggplant skin fraction (Solanum Melongena Var. Serpentinum L.) as an in vitro sunscreen
Authors: Sari Salza Laila , Wulandari Wulandari , Mutiara Erlita Verdia
Published: August 2024

Sunscreen is a product that is used as skin protection against sun exposure. The skin of purple eggplant is known to contain secondary metabolites which are used as sunscreens. This study aims to determine the activity of sunscreen fraction of the purple eggplant (Solanum melongena var. serpentinum L.) in vitro. Testing of sunscreen activity was carried out by calculating the value of SPF (Sun Protection Factor), %TE (Percent Transmission of Erythema) and %TP (Percent Transmission of Pigmentation) using the UV-Vis Spectrophotometry method. The purple eggplant skin fractionation method is by using LVC (Liquid Vacuum Chromatography). The results of the fractionation were identified using phytochemical screening and combined TLC. The fraction results were tested for SPF (Sun Protection Factor), %TE and %TP values. The results showed that the extract yield was 26.33%. The fractions used are fraction 9; 10; 11; and 12 which showed the same stain after being evaporated, which was a brownish yellow stain with a yield of 21,24%. The purple eggplant skin fraction (Solanum melongena var. serpentinum L.) has SPF, %TE and %TP values with optimal protection at a concentration of 400 ppm with each value obtained being 19; 1.35 and 9.79. The results of the statistical test of the purple eggplant skin fraction showed that the data were normally distributed but not homogeneous. The results of the homogeneity test for each concentration of results showed that the data were not significantly different.
Effects of Substituting Corn Meal for Corn Cob Meal on Diets Acceptability, Growth Response and Cost of Diets Fed to Catfish (Clarias Gariepinus)
Authors: C. J. Okeke, , J. E. Eyo, , O. A. Okeke, , E. I. Azaka, , P. C. Akwuaka, , I. S. Okpani,
Published: August 2024

A seventy -day feeding trial was conducted to assess the replacement value of corn cob meal as a dietary replacement for corn meal in diets of Clarias gariepinus. The corn cob was treated with 2% NaOH. The treatment reduced the fibre and increased the protein contents of the corn cob. Six isonitrogenous (40% crude protein) diets were formulated and corn cob meal was included in the diets at 0%, 10%, 20%, 30%, 40%, 50% and 100% inclusion levels designated as diets A, B, C, D, E, F, and G respectively, and diet H (commercial Coppens fish feed). The acceptability of the diets was studied using the time to strike the pellets and the acceptability index. The growth response and cost of diets were estimated. Results indicated that substituting corn meal with corn cob meal in diets fed to C. gariepinus juveniles increased the time taken by fish to strike dietary pellets. The higher the proportion of corn cob meal in the diet, the lower the acceptability of the diet to the fish. The least acceptable diet was diet G. The fish fed diet H recorded better weight gains and specific growth rate followed by the control diet and diet C respectively. There were significant differences between the control diets and the experimental diets (P < 0.05). The cost-benefit analysis showed that catfishes fed the control diets had a comparatively lower cost of diet per unit weight gain than the fish fed the corn cob-based diets. This was closely followed by diet C. This study demonstrated that corn cob meal can be successfully used to replace corn meal in the diets of Clarias gariepinus at inclusion levels of up to 30% but it is efficacious and cost-effective at a 20% inclusion level.
Economic Analysis of Fluted Pumpkin Production in Kolokuma/Opokuma Local Government Area of Bayelsa State, Nigeria
Authors: N. C. Morgan, , P. E. Kainga, , V. O. Chukwu, , S. Ibe,
Published: August 2024

The study examines the economic analysis of fluted pumpkin production in Kolokuma/Opokuma Local Government Area of Bayelsa State, Nigeria. A structured questionnaire was used to obtain the required information from the fluted pumpkin farmers. Both descriptive and inferential statistics such as frequency, percentages, mean, stochastic frontier production and budgetary model were used. The results indicate that married female farmers made up the majority of the 38.5% of farmers, with individuals between the ages of 31 and 40 on average. The variables that increased the fluted pumpkin technical efficiency were age, education level, and agricultural experience, according to the stochastic model. Age, farm experience, and transportation all had a significant impact on the production of fluted pumpkins at different probability levels. The total cost incurred was ₦703,453.07. The returns from the study amounted to ₦1,146,295.37, thereby, making the Net farm Income ₦442,841.64. The rate of return on investment (ROI) was 0.65. The return on investment of 0.65 indicates that every N 1.00 naira invested returns N 0.65 to the enterprise. This is an indication of a high return. The study identified that inadequate credit facilities, high rate of flooding, insufficient storage facilities, lack of labour/high cost of labour and little or no capital to start were the major problems of fluted pumpkin farmers. It was therefore recommended that the government provide farmers the mean of accessing reasonable price for farm input at the appropriate time.
Using a Mathematical Model to Evaluate the Efficiency of Memory Allocation Algorithm
Authors: P. O. Ogba , M. Bello
Published: August 2024

One of the key research areas in operating systems is memory allocation and process management by the operating system. Memory allocation is the process of allocating blocks of memory to different executing processes in order to improve overall system performance. This paper analyses the efficiency of memory allocation algorithms (first fit, best fit and worst fit) in the multiple partition and contiguous memory allocation scheme. A Mathematical model was used on process sizes in terms of percentage internal fragmentation (IF%), percentage external fragmentation (EF%), and percentage total utilization (TU%), this was done to compare the performance of the memory allocation algorithm. Results from the analysis show that the best fit made more efficient use of the available memory space than that of first-fit and worst fit.
Comparative assessment of the impact of renal denervation on blood pressure values in resistant hypertensive patients with and without type 2 diabetes
Authors: Caraus Alexandru , Moiseeva Anna , Abras Marcel , Surev Artiom
Published: August 2024

Randomized clinical trial data confirm the effectiveness of renal artery denervation (RDN) not only among hypertensive patients, but also in other pathologies associated with increased SNS activity, such as type 2 diabetes, heart failure and others. Aim. Evaluation of the impact of RDN on blood pressure values in two categories of patients - resistant hypertension with and without type 2 diabetes. Materials and methods. The randomized prospective clinical study was designed that enrolled 250 resistant hypertensive patients divided into two equal groups of 125 patients depending to the presence of DM. The patients in the first two subgroups of each group were given standardized treatment supplemented with SNS blockers Moxonidine and Bisorpolol , while patients from subgroups III and VI underwent RDN. Patients were evaluated by dynamic ambulatory BP monitoring for a period of 3 years. Results. Authentic reduction of office SBP and DBP was noted starting from 6 months of assessment in all research groups, the comparative analysis of dynamics of office SBP at all stages of evaluation demonstrating a clear superiority of groups of minimally invasive treatment by RDN versus pharmacological treatment with the SNS blockers Moxonidine and Bisoprolol in improving these parameters. At the same time, a statistically significant reduction in the average values of SBP and DBP 24 hours was recorded in both the pharmacological and interventional treatment groups independent ofthe presence of type 2 diabetes, the maximum antihypertensive effect being expressed at 36 months of evaluation. Diabetic and non-diabetic patient groups undergoing RDN demonstrated superiority to both pharmacotherapeutic regimens at all follow-up stages.Conclusions. The obtained results demonstrated the comparable antihypertensive efficacy of RDN in resistant hypertensive patients with or without type 2 diabetes. At the same time, the groups of diabetic and non-diabetic patients undergoing RDN showed superiority over both pharmacotherapeutic regimens with SNS blockers in reducing blood pressure values, the beneficial effect being maintained for a three-year follow-up period.
The evolution of cardiac function in patients with non-Hodgkin’s lymphoma under chemotherapy
Authors: Bursacovschi Daniela , Revenco Valeriu , Robu Maria
Published: August 2024

In clinical practice, the treatment of non-Hodgkin’s lymphoma (NHL) often involves the combination of several chemotherapy agents, radiotherapy and immunotherapy. While these multimodal approaches improve the efficacy of pathology-specific treatment, they also increase the risk of cardiovascular complications, the most common of which is ventricular dysfunction induced by anti-tumor therapy. Aim of the study: Evaluation of the impact of anti-tumor treatment of NHL on the trajectory of left and right ventricular echocardiographic function. Materials and methods: 127 randomly selected patients from the hematology departments of the PSMI Institute of Oncology were included in the study. Patients were investigated during 3 visits by comprehensive echocardiography, the first visit was up to the onset of anti-tumoral treatment, the 2nd visit was 1 month after initiation and the 3rd visit at 6 months after the debut of chemotherapy. Results: During the anti-tumor treatment, a statistically significant decrease in left ventricular systolic indicators was attested by following parameters: left ventricular ejection fraction (LV EF), mean left ventricular S’, the ratio between the maximum velocity of the E wave and the flow propagation velocity (E/Vp), with an ANOVA p-value <0.001. Regarding the right ventricular systolic function, the indices reflected by TAPSE and S’ right ventricular free wall were reduced statistically significantly also (p ANOVA <0.001). The given analysis confirmed the impairment of ventricular relaxation throughout the treatment, the increase in left ventricular filling pressures, the ratio E/A and E/e’ showed a statisticallysignificant increase, parameters such as the deceleration time of the E wave, the relaxation isovolumetric time, the ratio e’/a’ did not register a statistically significant dynamic (p ANOVA = 0,897; 0,705 and 0,145 respectively). 6 months after the start of treatment, cardiac dysfunction associated with cancer therapy (CTRCD) was found in 18 patients (14,2%), 8 (6,3%) presented a moderate asymptomatic form, 7 (5,7%) had a mild asymptomatic form and 3 (2,4%) a symptomatic one.Conclusion: The left ventricular systolic function was statistically significantly reduced under the impact of the applied treatment, which was confirmed by the LV EF, the mean S’ value at the LV and the E/Vp ratio, the diastolic function having an impact through the E/A and E/e’ ratio. Regarding the function of the right ventricle, we attested statistically significant changes only in the longitudinal contraction parameters. CTRCD was confirmed in 18 patients.
New approaches in cardiovascular risk estimation and stratification
Authors: Grosu Aurel , Marina Angela , Rudi Victor
Published: August 2024

Cardiovascular diseases remain a significant and growing problem in the Republic of Moldova, representing more than half of all deaths and leading to significant morbidity. It is now recognized that the burden of cardiovascular disease (CVD) can be ameliorated by vigorous risk reduction and primary prevention, which remain an important priority for all health policy developers. Being one of the European countries with a high risk for cardiovascular diseases, Moldova faces major difficulties in implementing CVD prevention measures both at the population and individual level. This article summarizes the main novelties of the guidelines for the prevention of cardiovascular diseases of the European Society of Cardiology (ESC), recently published, examining their positive aspects, but also their applicability to routine clinical practice, taking into account the socioeconomic characteristics of Moldova. Cardiovascular risk estimation is an essential step to reduce the onset of adverse cardiovascular events. For this purpose, the Systematic Coronary Risk Evaluation (SCORE) risk chart method was used in Europe. The effort to prevent atherosclerotic CVD is focused on identifying patients who would benefit mostly from the treatment of CVD risk factors.
Updates in the management of patients with non-obstructive coronary artery disease
Authors: Dicusar Olga , Caragea Tatiana , Munteanu Mihaela , Ivanov Victoria , Popovici Mihail
Published: August 2024

A large majority (up to 70%) of patients undergoing coronary angiography because of angina and signs of myocardial ischemia do not have obstructive coronary arteries. The studies carried out in the last decades have shown that microvascular coronary dysfunction (CMD) and epicardial vasospasm are the basic pathophysiological mechanisms of non-obstructive coronary artery disease (CAD), and depending on the underlying mechanism, three clinical endotypes are differentiated: microvascular angina, vasospastic and mixed. Correct diagnosis and endotype-specific treatment of non-obstructive CAD is shown to be associated with a better quality of life and a more favorable long-term prognosis. Patients with non- obstructive CAD require a strict control of their cardiovascular risk factors. Statins and ACE inhibitors have beneficial effects in most patients. First-line anti-anginal treatment are beta-blockers and/or calcium channel blockers, depending on the underlying mechanism (microvascular or vasospastic coronary dysfunction). Second-line drugs are ivabradine, ranolazine, and nicorandil. Rho-kinase inhibitors and endothelin receptor antagonists represent potential drugs for the treatment of these patients in the future.
Some clinical dilemmas in medication with inhibitors of the renin-angiotensin-aldosterone system in patients with heart failure
Authors: Popescu Liuba , Caraus Alexandru
Published: August 2024

Use of renin-angiotensin-aldosterone system inhibitors in patients with heart failure and reduced ejection fraction is associated with functional improvement, an increase in perceived quality of life, a reduction in the probability of cardiovascular death, and a decrease in the number of hospitalizations. Some of these drugs are also efficacious in patients with chronic kidney disease and albuminuria as well as in patients with resistant hypertension. Despite their numerous benefits, renin-angiotensin-aldosterone system inhibitors are associated with an increase in incidence of hyperkalemia, especially in patients with concomitant chronic kidney disease. Hyperkalemia is a common electrolyte disorder that is defined as an elevation in plasma concentrations of potassium above 5 mEq/L. It has been related to rehospitalizations, malignant arrhythmias, and an increase in mortality. On the other hand, optimized treatment with renin-angiotensinaldosterone system inhibitors requires progressive dose increases which can in turn entail a greater probability of hyperkalemia.
Proinflammatory status in patients with ischemic heart failure in the setting of obesity paradox
Authors: Gutan Inesa
Published: August 2024

Obesity is an independent predictor of cardiovascular disease, with an increased risk in primary prevention, but according to several studies, the potential protective effect of obesity when it coexists with cardiovascular disease has been demonstrated, a phenomenon called the „obesity paradox”.While previous research has shown that inflammatory mediators have been associated with shorter survival, the effect of inflammation on the association between obesity and heart failure has not been considered. Adipose tissue is known to have a crucial role in regulating inflammation and metabolic homeostasis, but some aspects of chronic inflammation also have an adaptive or compensatory effect under certain conditions in obese individuals.In this context, it is important to investigate the mechanisms of the protective effect of obesity in relation to heart failure in order to understand this paradox and develop more effective treatment strategies.
Antihypertensive effect of the SGLT2 inhibitor dapagliflozin in patients with type 2 diabetes
Authors: Cotelea Ana , Cociu Maria , Popescu Liuba , Moiseeva Anna , Caraus Alexandru
Published: August 2024

Chronic pathologies that disable over time, such as hypertension and type 2 diabetes, remain among the top targets of international studies and approaches. That’s why the scientists, as well as the staff of the practical bases, have nothing left but to impose the development and implementation of the new preparations, which would be able to meet their needs. An important step would be to synthesize drug molecules with positive effects in concomitant pathologies, which most often meet in pairs or complement each other through the adverse effects they produce on the human body. Such a preparation, which is currently approached through the prism of the multitude of positive effects, is in full company of implementation in the treatment of several chronic pathologies such as type 2 diabetes mellitus, chronic heart failure, chronic renal failure and makes part of the group of SGLT 2 inhibitors is the dapagliflozin.The antihypertensive effect of dapagliflozin is relevant and requires a well-documented analysis in this direction
The individualized approach in heart failure with preserved ejection fraction. From clinical practice to Artificial Intelligence
Authors: Jitari Inessa , Savca Dmitri , Ochișor Viorica , Revenco Valeriu , Cabac-Pogorevici Irina
Published: August 2024

In the last 2 decades heart failure has received a lot of attention; however, little therapeutic progress has been recorded. Globally, more than 60 million people suffer from heart failure, and its prevalence is constantly increasing. Identifying the specific clinical entities and comorbidities associated with different phenotypes of heart failure with preserved ejection fraction may have important clinical implications as it may help guide the development of targeted therapies for these subtypes. Identification and characterization of heart failure phenotypes with preserved ejection fraction is important for guiding diagnosis, management, and research into new treatment strategies.
THE PREVALENCE OF DYSLIPIDEMIA IN THE POPULATION OF THE REPUBLIC OF MOLDOVA (PRELIMINARY DATA)
Authors: Șeremet Aristia , Vudu Stela , Uzun Tatiana , Cazac Nadejda , Fedas Vasile , Furdui Vlada , Piterschi Carolina , Bacinschi-Gheorghita Stela , Dusa Ina , Ambros Tatiana , Caradja Gheorghe , Arnaut Oleg , Vudu Lorina
Published: August 2024

Dyslipidemias are among the most important modifiable risk factors associated with cardiovascular pathology. Materials and methods. The preliminary results of the observational, cross-sectional study conducted from February 2020 to January 2023 are presented. The prevalence of dyslipidemia and the lipid profile in a sample of 728 participants from rural and urban environments were analyzed. Results: In a group of participants with a mean age of 47.14 ± 12.65 years, it was observed that elevated LDL- cholesterol and decreased HDL-cholesterol levels were the most frequent abnormal lipid parameters in men, and in women isolated elevation of LDL-cholesterol was often recorded. Conclusions: The study emphasizes the importance of early screening in apparently healthy populations. Early diagnosis may identify high-risk population groups, where early intervention may lead to avoidance of later complications related to dyslipidemia.
Learning in Times of Crisis: Insights into Student, Teacher, and Parent Experiences in Uttarakhand's Educational System during the COVID-19 Pandemic
Authors: Kumar Pant Ashish , Kumar Pant Mayank , Sah Ila
Published: August 2024

The COVID-19 pandemic, declared in 2020, posed unprecedented challenges globally. Governments throughout the world adopted steps to lessen the effect of the infectious sickness brought on by the SARS-CoV-2 virus, including extensive lockdowns and closures of educational institutions. The current study looks at the effects of the pandemic on the educational landscape of Uttarakhand, an area distinguished by its distinct physical and socioeconomic characteristics. Amidst the closure of schools and universities, the transition to online learning became the norm, presenting significant hurdles for students, teachers, and parents, particularly in areas with limited access to digital resources. This study, based on a sample of 667 respondents, employs the snowball sampling method to examine the experiences and challenges faced by stakeholders in Uttarakhand's educational system during the lockdown period. By exploring the multifaceted impacts on learning environments, instructional delivery, and parental involvement, this research aims to provide valuable insights into the adaptation strategies and resilience of individuals within the education sector during times of crisis.
Pradhan Mantri Ujjwala Yojana: An Initiative of Government towards Better Life for all
Authors: Suman Ravindra
Published: August 2024

The Honourable Prime Minister of India announced the beginning of the Pradhan Mantri Ujjwala Yojana (PMUY) on May 1, 2016. The scheme's primary goal is to give women from low-income households access to LPG connections without requiring a payment. The government's goal was to provide 5 crore LPG connections to low-income families in rural India, with a focus on women living below the poverty line (BPL). Later, the goal was raised to 8 crore, which was accomplished on September 7, 2019, seven months ahead of schedule, under the Ujjwala Yojana Scheme, which went under the slogan "Swachh Indhan, Behtar Jeevan.
The Quit Kashmir Movement 1946
Authors: Bashir Lone Mansoor
Published: August 2024

The Cabinet Mission aimed to negotiate the transfer of power and the future structure of government with Indian leaders particularly with the Indian National congress and Muslim league. The future of the princely states was one of the mission's most major concerns. As soon the members arrived in Kashmir, Sheikh Mohammad Abdullah the president of the National Conference submitted a memorandum to its members that demanded not just a responsible government under the aegis of the Maharaja but also the Kashmiri people's right to absolute freedom from the autocratic rule of the Dogra House. The Quit Kashmir movement was launched to pressure the oppressive Dogra government to grant sovereignty to the people of Kashmir. The National Conference by launching the Quit Kashmir had emerged as a principal national organization advocated for political, social, and economic changes to end privilege and raise the masses. The Dogra despot’s barbarism was unashamed in trampling unwarned people who dared to speak the truth and demand their freedom. This paper explores the circumstances that led Sheikh Abdullah to start the Quit Kashmir Movement and highlights the state response against the Movement.
Higher Education: Innovation and Practices
Authors: Fatima Khan Shaheen
Published: August 2024

The term "innovation" describes any new modification to a method or service. Under innovation, some new concepts or technological advancements are included. Innovation is accepted as a response to the fresh demands and needs of the current situation. Thus, it can be said that Innovation in its contemporary meaning is "a unique ideas, critical thinking and novel imaginations in form of techniques or methods". Technology and science ought to permeate every aspect of education and engage students in hands-on learning. In light of that, it is now acknowledged that innovation in education is important. Innovation is very important for the teacher, the learner and the teaching-learning process. There are many techniques and methods through which the teaching-learning process can be made more interesting and effective. This paper will throw light on new innovative methods, their relevance in education and the quality of teachers for innovative teaching.
A study of Rural Women's Health
Authors: V. Patel Sanjay
Published: August 2024

According to the World Health Organization, health is not merely the absence of disease but a state of complete physical, mental and social well-being. The real meaning of being healthy is focusing on yourself and adopting healthy ways of living. After independence in India, health has been one of the main goals facing the country. There have always been obstacles in bringing health facilities to the rural people of the country. The average life expectancy of people in India increased from 32 years in 1951 to 64.6 years for men and 67.6 years for women in 2011. If we look at the nutritional status of women and adolescents in India, 58% of pregnant women are anaemic. 33% of malnourished women, 30% of married women under the age of 18 and 42% of women with low weight during pregnancy. A study unit of 10 villages has been selected from each taluka of Bhavnagar district.
A total of 300 women namely 30-30 rural women from each village have been purposefully selected through Yadachh demonstration method. In the present study, 62% of the respondents have common illnesses like cold, cough, fever, and headache, in modern times, very few people take home remedies during the treatment of the illness, while the maximum number of respondents take the treatment in the hospital. There is a government hospital facility in their village to a small extent, while there is a small amount of private hospital, the government health worker comes to their village to a very small extent, 68% of the respondents say that the doctor comes regularly to the health center of their village, 69% of the subjects under study. The respondent is getting satisfactory advice from the employee. In the present study, more than half of the respondents have to pay the expenses of the illness to their husbands, while less amount have to be paid by themselves. In the present study maximum respondents know about Ma Amritham Yojana but take little benefit of it. In the present study only 8% respondents deliver at home. While 28% of the respondents give birth in a hospital and 42% in a private hospital. In the present study, rural women suffered from many health related problems due to economic factors. In the present study also more health related problems have been observed in uneducated women as compared to educated women. Overhead delivery is very harmful to a woman's health. Rural women have a high rate of miscarriage due to lack of education and awareness or other family reasons that negatively affect their health. Even today, there is a tradition in the rural society that after all the men in the house have eaten, the women eat, due to which there is not enough food left. This leads to malnutrition among rural women and this condition of malnutrition over time creates serious diseases. These health issues arise in villages under study where facilities are lacking.