bluuebunny/crossref_metadata_2025 huggingface dataset:
Potential of an Integrated Platform for EV Charging Station and Ancillary Services
Authors: Qin Yanrui , Luo Yuling , Yu Yangtao , Ren Lindsey , Wang Haoran
Published: August 2024

Since the creation the first successful electric car in 1890, the world has seen a rapid increase in the advancement of Electric Vehicle (EV) cars along with increasing demand for such vehicles. However, despite multiple benefits that EV cars offer, such as their sustainable nature, potential car buyers are still hesitant on purchasing an EV car due to concerns about its relatively short travelling range. While the technology powering EV cars has made significant strides, petrol cars can travel much further on a single tank of fuel than EV cars can on a single charge: electric cars can only travel between 100-300 miles on a single charge, whereas gas cars have a range of 300-600 miles. Furthermore, infrastructure is another benefit that gas-powered vehicles have over electric ones. Particularly in rural areas, gas stations are far more common and easily accessible than charging stations. While some owners of electric vehicles might be able to charge their vehicles at home or at the office, they might have trouble finding charging stations when they are out and about. Hence, EV drivers or potential car buyers share a common concern that EV cars will run of gas frequently, leading to inconvenient trips to gas stations. Through our research, by abstaining user experience and feedback, we were able to identify substantial demand for a platform or service that improves the accessibility of EV charging stations for EV car drivers. This paper will include a thorough representation of relevant results and a deep analysis on the potential of a platform that provides easily accessible charging stations as well as other car-related services.
Commercial Application of Artificial Intelligence in Chinese Pan-mental Healthcare Industry
Authors: Yang Jinxiao , Wang Yifei , Liu Ziyi , Song Shixuan
Published: August 2024

In the modern educational landscape, the mounting academic demands imposed on adolescents, coupled with a noticeable trend of enrolling children into formal schooling at increasingly younger ages, have become influential factors in the exacerbation of emotional stress experienced by young individuals. This burgeoning concern for mental health matters within contemporary society necessitates a heightened level of attention and thorough investigation. This comprehensive report unfolds as an intricate exploration of multifaceted dimensions. It begins with a meticulous literature review, which delves into the existing body of knowledge surrounding the issue. Subsequently, the report investigates the practical applications of AI in the domain of mental healthcare, recognizing the potential benefits and advancements AI technology can bring to the field. Moreover, an external analysis is conducted to contextualize the broader societal and environmental factors contributing to the observed challenges. A competitive landscape assessment is performed to understand the existing solutions and their strengths and weaknesses. Further, strategies related to market segmentation and targeting are formulated to better address the diverse needs of the audience. The report also provides a detailed description of the target customer base, offering insights into the demographics and psycho-graphics of the individuals who stand to benefit most from the proposed AI-driven solution. A mock product is meticulously designed, integrating the learning from the aforementioned analyses. Furthermore, conjoint analysis and data analysis techniques are applied to discern the nuanced preferences and needs of the target audience. The study, rooted in empirical research, investigates the intricate web of psychological challenges teenagers face in present-day society. In response to the identified issues, the report outlines the development of an AI-exclusive application. This application is thoughtfully tailored to ameliorate the mental health challenges specific to teenagers, offering a promising avenue for providing timely and effective support to this vulnerable demographic.
The Combined Effects of Financial and Market Indicators on the Valuation of New Listings: Evidence from the Biopharmaceutical Sector
Authors: Ji Xianzhe
Published: August 2024

This study confirms that financial and market data have a significant impact on the valuation of newly listed companies, especially in the biopharmaceutical industry. Using multiple linear regression models, this paper found significant differences in the impact of EBITGR and EBITDAGR on price-to-earnings ratio (P/E Ratio) across years. Other indicators such as Total Asset Turnover, Return on Assets (ROA) and Debt to Equity Ratio (D/E Ratio) have weaker explanatory power and unstable influence. In addition, fluctuations in market valuations of listed companies are influenced by market sentiment and the macroeconomic policy environment. In high-growth, high-risk industries such as biopharmaceuticals, regulatory policies and listing structure reforms in the market can cause structural changes in model performance. At the same time, changes in market sentiment and regulation can also affect the explanatory power of financial indicators to some extent. Further analyses showed that market preferences for valuation changed over time during the study period, especially when the market moved significantly, driven by regulatory policy and the external environment. This makes the conclusions of the study's findings subject to uncertainty in different market environments. Overall, this study reveals a number of key factors affecting the market valuation of newly listed companies and highlights the importance of the interaction between market data and financial indicators. In future research, more attention should be paid to the role of different time periods, market conditions and industry characteristics to avoid potential valuation traps and provide more informative support to market investors and managers.
Manajemen Layanan Teknologi Informasi Perusahaan Perseroan Menggunakan Information Technology Infrastructure Library Service Operation: Literature Review
Authors: Tjonadi Callista , Wijaya Khellyn Viorensa , Roselin Vanesia , Natalie Vellyn , Maulana Ade
Published: August 2024

At this time, information technology is growing rapidly in various business fields. To provide good service, IT Service Management is implemented. Service Management can provide value to be implemented by companies, one of which is by implementing the ITIL framework which consists of several services but in this journal will focus on Service Operations. The research method applied is qualitative research which analyzes the data in depth. From the results of the research conducted, it is known that there are several companies that have not implemented Service Operations optimally, even so Service Operations still have a role within the company. The processes contained in Service Operations such as Event Management, Problem Management, Incident Management, Request Fulfillment, and Access Management have an important role so that the systems within the company's companies run according to the goals and wishes of customers, there are implementations made to assess IT service operations which will show the maturity level of existing processes, some create strategies using Customer Relationship Management, some create SOPs using the PDCA method, and some implement Service Operations by improving services.
Tinjauan Terhadap Implementasi Enterprise Architecture: Analisis Perbandingan Studi Kasus Industri Kesehatan
Authors: Chandra Carissa , Young Jian , Salim Jodie , Onggie Karen , Kimberly  , Andriano Vinson
Published: August 2024

This paper discusses the review of the implementation of EA (Enterprise Architecture) in the healthcare industry through a comparative analysis of case studies using two frameworks namely TOGAF ADM and Zachman. The purpose of writing this paper is to identify the strengths and weaknesses of the implementation of each case study, as well as provide an understanding of the use of frameworks in the health industry. The type of analysis in this paper is a qualitative analysis using five papers containing case studies from different health companies which implement the ADM and Zachman TOGAF framework. The results of the analysis show that the two frameworks have different approaches in dealing with certain challenges and needs of the healthcare industry. In addition, there is the use of a matrix, namely the TOGAF framework which aims to provide an overview of the relationships and dependencies between the elements of the two frameworks. After doing the analysis and matrix, it can be concluded that the two frameworks are able to influence EA in the health industry. Thus, making it easier for companies to plan, design, manage, and implement enterprise architecture in an effective and efficient manner.
Perancangan Sistem Informasi Kedai Kopi Menggunakan Metode Rapid Application Development (RAD)
Authors: Ardhana Valian Yoga Pudya
Published: August 2024

The development and speed of information technology in the industrial revolution 4.0 requires companies or business people to switch to using systems that are able to work together and collaborate between technology and human resources. Current technological developments also have an impact on MSME business actors, especially culinary. For example, coffee shop, usually in the ordering process, coffee shops still use a manual ordering process. In this process, customers who come in must enter, order and immediately pay manually. This is of course risky for the company because the data could be lost or damaged. This problem occurs because there is no system that can support the ordering process, manage incoming data, market and introduce the product to reach the wider community. Customers sometimes find it difficult to get the latest updated information regarding available menus and the ordering and payment process. For this reason, an information system is needed so that problems can be resolved. With the Rapid Application Development (RAD) approach, the coffee shop information system can be developed relatively quickly and produce a system that suits your needs. This web-based coffee shop information system has the features that coffee shop entrepreneurs need to run their business effectively and efficiently and makes ordering and payment easier for customers. Apart from that, the test results using black-box testing produced a score of 100%, this means that the features contained in the system are in accordance with requirements.
PROFIL KOMORBID OBESITAS, HIPERTENSI, DAN DIABETES MELITUS TIPE II PADA LANSIA DENGAN ATAU TANPA PENYAKIT KATARAK
Authors: Putri Nanda Lessi Hafni Eka , Nathaniel Fernando , Wijaya Dean Ascha , Tadjudin Noer Saelan , Firmansyah Yohanes
Published: August 2024

Katarak terus menjadi penyebab utama kebutaan dan gangguan pengelihatan yang paling signifikan. Katarak menyumbang sekitar 50% dari total 285 juta orang yang mengalami gangguan penglihatan di seluruh dunia. Katarak dikaitkan dengan banyak penyakit sistemik terutama diabetes melitus, hipertensi, obesitas, penyakit ginjal kronis dan penyakit autoimun. Dengan beban penyakit yang besar dan ketersediaan sumber daya yang terbatas, identifikasi faktor risiko sangat penting untuk menerapkan strategi penanganan yang efektif dan efisien. Penelitian potong lintang ini bertujuan untuk mengetahui profil komorbid obesitas, hipertensi, dan diabetes melitus tipe II pada lansia dengan atau tanpa katarak di Panti STW Ria Pembangunan yang dipilih sesuai kriteria secara total sampling menggunakan data yang tercatat pada tahun 2018 – 2019. Variabel dalam penelitian ini yaitu kejadian katarak, status gizi, diabetes melitus tipe II dan hipertensi. Data disajikan dalam bentuk deskriptif. Dari 63 responden, katarak umumnya terjadi pada usia old (75 – 90 tahun) pada 33,3% responden, perempuan pada 47,6% responden, tidak obesitas pada 49,2% responden, tidak diabetes melitus pada 41,3% responden, dan hipertensi pada 46% responden. Seluruh hasil ini merupakan perbandingan dengan seluruh sampel baik yang katarak maupun tidak. Temuan penelitian ini menyatakan sebagian besar responden yang memiliki katarak tidak mengalami obesitas dan tidak memiliki diabetes melitus, tetapi memiliki hipertensi. Hasil penelitian ini diharapkan membantu menguraikan beberapa komorbid yang ditemukan pada lansia dengan atau tanpa katarak agar diciptakan suatu strategi modifikasi gaya hidup yang kemudian mengurangi morbiditas dan beban finansial pada lansia secara global.
Термодинамика идеального электронного газа, локализованного в тонком сферическом нанослое CdSe
Authors: Тадевосян Л. А. , Степанян В. А. , Калтахчян А. Т. , Мамасахлисов Е. Ш. , Саркисян А. А.
Published: August 2024

Исследованы термодинамические характеристики электронного газа, локализованного в тонком сферическом нанослое CdSe. Размеры CdTe/CdSe квантовой точки типа ядро–оболочка считаются большими, что позволяет считать газ идеальным. Вследствие малой толщины структуры спектр частиц имеет подзонный характер, когда с каждым уровнем размерного квантования связано семейство уровней сферического ротатора. В рамках больцмановской статистики определена статистическая сумма для исследуемого газа, и определены средняя энергия, энтропия и теплоемкость такого газа. Изучены зависимости термодинамических характеристик указанного электронного газа от геометрических параметров квантовой точки CdTe/CdSe.
Ուսումնասիրվել են CdTe/CdSe միջուկ-թաղանթ քվանտային կետի բարակ գնդոլորտային CdSe նանոթիթեղում տեղայնացված էլեկտրոնային գազի թերմոդինամիկական պարամետրերը։ Քվանտային կետի չափերը համարվում են մեծ, ինչը թույլ է տալիս գազը դիտարկել իդեալական։ Նանոթիթեղի փոքր հաստության շնորհիվ մասնիկների սպեկտրն ունի ենթագոտիական բնույթ, երբ սֆերիկ ռոտատոռի մակարդակների ընտանիքը կապված է շառավիղային քվանտացման յուրաքանչյուր մակարդակի հետ: Բոլցմանի բաշխման շրջանակներում որոշվել են ուսումնասիրվող գազի վիճակագրական գումարը, ինչպես նաև միջին էներգիան, էնտրոպիան և ջերմունակությունը։ Ուսումնասիրվել են վերոնշյալ էլեկտրոնային գազի թերմոդինամիկական բնութագրերի կախվածությունը CdTe/CdSe քվանտային կետի երկրաչափական չափերից։
The thermodynamic characteristics of an electron gas localized in a thin spherical CdSe nanolayer have been studied. The dimensions of the CdTe/CdSe core-shell type quantum dot are considered large, which allows the gas to be considered ideal. Due to the small thickness, the particle spectrum has a subband character, when a family of levels of the spherical rotator is associated with each radial quantization level. Within the framework of Boltzmann statistics, the statistical sum for the gas under study was determined, as well as the mean energy, entropy, and heat capacity. The dependences of the thermodynamic characteristics of the electron gas on the geometric parameters of a CdTe/CdSe quantum dot have been studied.
Волноводно-линзовые переходы терагерцового диапазона
Authors: Варданян В. А. , Айвазян М. Ц.
Published: August 2024

Исследована возможность применения диэлектрической линзы в качестве узконаправленной антенны терагерцового диапазона. Получены и проанализированы теоретические выражения, позволяющие рассчитать форму профиля линзы и диаграмму направленности созданной линзовой антенны. Показана эффективность предложенной линзовой антенны в указанном диапазоне, а также приведены результаты экспериментальных исследований созданной линзовой антенны.
The possibility of using a dielectric lens as a highly directional antenna in the terahertz range has been studied. Theoretical expressions have been obtained and analyzed that make it possible to calculate the shape of the lens profile and the radiation pattern of the created lens antenna. The effectiveness of the proposed lens antenna in the specified range is shown, and the results of experimental studies of the created lens antenna are also presented.
Full Title: Is epidural and subcutaneous fat tissue thickness associated with lumbar disc herniation?
Short Title: Epidural and subcutaneous fat tissue in disc herniation
Authors: Atik Irfan , Atik Seda
Published: August 2024

Objective: Lumbar disc herniations(LDH) cause important clinical symptoms such as low back pain(LBP) and have many causes. This study investigates the role of epidural and subcutaneous fat tissue thickness in LDH.
Materials and Methods: In this cross-sectional study, individuals aged 18-83 with lumbar magnetic resonance imaging (MRI) due to LBP were evaluated retrospectively between July 2023 and January 2024. According to lumbar MRI, they were divided into two groups: those with or without herniation. Both groups measured epidural fat tissue thickness(EFTT) and subcutaneous fat tissue thickness(SFTT) at all lumbar levels. The relationship between the two groups in terms of EFTT and SFTT was examined statistically.
Results: According to lumbar MRI, herniation was detected in 292 patients, and no herniation was detected in 300 patients. SFTT was found to be greater in the group with herniation than in the group without herniation at all lumbar levels (p = 0.0001). EFTT was lower in the group with herniation at all levels (p = 0.0001). In the group with herniation, there was a statistically significant correlation between the number of hernia levels and SFTT (r: 0.54, p: 0.0001) and EFTT negatively (r: -0.22, p: 0.0001).
Conclusion: An increase in SFTT thickness and a decrease in EFTT are associated with disc herniation. This relationship is a result of the mechanical and inflammatory damage caused by obesity. In addition, the relationship between herniation and the decrease in EFTT demonstrates the protective function of epidural fat tissue.
PREOPERATIVE AND POSTOPERATIVE LEVELS OF ANXIETY ACCORDING TO THE VISUAL ACUITY OF PATIENTS UNDERGOING CATARACT SURGERY
Authors: KESER Sinem , BARAN Ay , YILDIZ Sevler
Published: August 2024

Aim: To evaluate preoperative and postoperative levels of anxiety according to visual acuity and sociodemographic characteristics in patients undergoing cataract surgery.
Method: The study included 100 patients who were planned to undergo cataract surgery because of reduced vision. One day preoperatively and at one month postoperatively, all the patients were administered the sociodemographic data form and the Spielberger State-Trait Anxiety Inventory (STAI TX-1 and TX-2). All the patients underwent a detailed preoperative and postoperative ophthalmological examination. Visual acuity was evaluated with a logMAR Chart.
Results: The visual acuity on the LogMAR chart of the patients was mean 1.1±0.3 preoperatively and 0.1±0.1 postoperatively. Visual acuity was determined to have significantly increased postoperatively and the STAI FORM TX-2 points significantly decreased (p=0.04). The postoperative decrease in the LogMAR chart was statistically significant (p<0.001). A significant positive correlation was determined between the preoperative STAI FORM TX-1 points and the preoperative STAI FORM TX-2 points. The mean STAI FORM TX-1 points of the patients with an education level of middle school or below were found to be significantly higher than those of patients educated to university level or higher (p=0.012). The visual acuity (LogMAR) of patients who had previously received psychiatric treatment were found to be significantly lower than those of patients who had not received any psychiatric drug treatment (p=0.027).
Conclusion: Patients with cataracts are anxious in a general sense, independently of surgery. The increase in vision after cataract surgery is important in respect of decreasing levels of trait anxiety.
Evaluation of Sleep Quality in Patients with Tinnitus
Authors: Yemi Tu , lmaz Yavuz
Published: August 2024

Aim: Tinnitus is the perception of sound in the absence of auditory stimuli. Tinnitus may affect daily life activities and cause complaints of difficulty in concentration, emotional distress and sleep disturbance. The aim of this study was to evaluate the relationship between tinnitus and sleep quality.
Materials and Methods: Eighty-one patients (42 females, 39 males) with subjective tinnitus lasting more than 6 months in the last 6 months were included. Tinnitus handicap index (THI), Pittsburgh Sleep Quality Index (PSQI) and Insomnia Severity Index (ISI) questionnaires were used.
Results: There was a moderate statistically significant positive correlation between THI and both PSQI (r=0.411; p=<0.001) and ISI (r=0.436; p=0.003). As THI increased, PSQI and ISI increased.
Conclusion: Evaluating sleep quality is important in treatment planning to control tinnitus and improve the quality of life in tinnitus patients.
Keywords: Tinnitus; Sleep Quality; Questionnaire
Mefenamic Acid Reduces the Contractility of Isolated Uterine Smooth Muscle of Rat
Authors: ercan z , ar Emine , lu hsan , z Zeynep , Hekim M , l Ahmet , n Orhan , ru Meryem
Published: August 2024

Objective: Mefenamic acid is a nonsteroidal anti-inflammatory drug widely used for the treatment of pain and inflammation. The drug is indicated in patients with mild to moderate pain and inflammatory diseases, usually toothache, painful menstruation, muscle or joint pains and postpartum pain. There are not enough studies showing the effectiveness of this drug, which is significantly effective in gynecological pains, on the uterine contraction and relaxation mechanism. This study was carried out to investigate the effects of mefenamic acid on the uterine contraction and relaxation mechanism. Materials and Methods: In the study, seven female intact Sprague-Dawley rats in the diestrus period were used. Longitudinal myometrium sections of 1.2 cm length, 2 mm width and 1 mm thickness from animals were suspended in an isolated organ bath containing crebs solution. After the regulation period, mefenamic acid was administered at a dose of 300 μM. Contractile changes were monitored using an isometric transducer. Before and after the application, the area under the curve (AUC), frequency and peak to peak (p-p) values were normalized as % change. Statistical analyzes of the data were performed with the Paired Sample T test in SPSS 22.0 program. Results: Mefenamic acid caused a statistically significant decrease in the p-p, AUC and frequency values of spontaneous uterine contractions at 300 μM dose (p<0.001). Conclusion: Mefenamic acid has an inhibitory effect on uterine contractions. This drug, which is widely used in the clinic for menstrual pain caused by abnormal uterine contractions, especially in young women, may show its analgesic effect by inhibiting uterine contractions.
The Effect of Absorbable vs. Non-absorbable Fixation on Early Complications in Laparoscopic Transabdominal Preperitoneal (TAPP) Inguinal Herniorrhaphy
Authors: lu Mustafa
Published: August 2024

Objective : This study has compared the postoperative pain, scrotal edema, seroma, bleeding or other complications between two patient groups getting laparoscopic transabdominal preperitoneal (TAPP) herniorrhaphy and where absorbable and non-absorbable fixations (3/0 prolene suture) were used in mesh fixation compared with such complications as hematoma, urinary retention, and recurrence.

Materials and Methods : 44 male patients getting laparoscopic TAPP herniorrhaphy method were included in this study. According to the material used for mesh fixation, they were divided into two groups getting absorbable or non-absorbable fixations. The age, gender, hernia type and direction according to the Nyhus Classification , and the fixation material used intraoperatively were all recorded for patients. 1st week, 1st month and 6th month postoperative checks were made. Early complications at the postoperative period were compared between groups. Patients gave written and informed consent before surgery.

Findings : Of the 44 patients, absorbable fixation devices were placed in 27 and non-absorbable ones in 17. At the 1st week follow-up, scrotal edema was diagnosticated in 3 patients in the absorbable group and in 2 in the non-absorbable ; seroma in 5 patients in the absorbable group and in 2 in the non-absorbable ; mild pain in 3 patients in the absorbable group and in 5 in the non-absorbable.
A significant relationship was not statistiscally found between the presence or absence of scrotal edema, or of seroma, pain intensity and the fixation material used (p>0.05).

Conclusion : A significant difference was not found when early complications were statistically compared between the patients getting laparoscopic TAPP herniorrhaphy and having used absorbable and non-absorbable fixation devices. It seems both fixation materials can be used safely.
Evaluation of central sensitization and presence of neuropathic pain in patients with rheumatoid arthritis and its relationship with quality of life
Authors: Gungor Zeynep , Sas Senem
Published: August 2024

Central sensitization and neuropathic pain may develop in rheumatological diseases. This study aimed to investigate the presence of central sensitization and neuropathic pain in patients with rheumatoid arthritis (RA). We used the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) questionnaire to evaluate neuropathic pain (NP) in patients with RA. The presence of central sensitization in patients was evaluated using the central sensitization inventory (CSI). Demographic and clinical data were obtained from patients and interviews. Beck Depression Scale (BDS) was used to evaluate the mood of the patients, and the Short Form-36 (SF-36) quality of life scale was used to evaluate the quality of life. A total of 104 patients participated in our study, and 33 (31.7%) of them were found to be NP. CSI scores indicated central sensitization in 41 (39.4%) of the patients. A positive significant relationship was detected between LANSS and Visual Analog Scale (VAS), BDI, and Disease Activity Score 28 (DAS28). Central sensitization (CS) and neuropathic pain (NP) significantly contribute to functional disability in RA patients. Central sensitization and neuropathic pain significantly contribute to functional disability in patients experiencing neuropathic pain, with CS having a detrimental impact on their quality of life. Thus, it is imperative to consider neuropathic pain and CS during disease monitoring and follow-up.
Impact of the COVID-19 Pandemic on Radiotherapy Patients by Age and Residence
Authors: Kolarevic Goran
Published: August 2024

Background/Aim: This epidemiology study aimed to investigate how the COVID-19 pandemic affected the weekly number of external beam radiotherapy (EBRT) fractions concerning patient age and residence distance from our radiotherapy center (RTC). Methods: Twenty-two-month intervals before and after the onset of the COVID-19 pandemic were compared. Results: The average weekly number of fractions from May 2018 to February 2020 was 692.8 (SD 67.6), and from March 2020 to December 2021 was 639.3. (SD 84.7). The weekly number of fractions decreased by 42.4 % in March 2021 and by 67.9 % in April 2020 compared to the same period in 2019. When comparing patients under 70 years of age to those over 70, the decrease was 28.0 % vs. 6.9 %, respectively. According to the Wilcoxon signed-rank test (Z = - 5.2, p = 0.001), the outbreak of the COVID-19 pandemic had a statistically significant impact on the decrease in the weekly number of fractions. The distance between the city of residence and the RTC was not a significant factor but years of life (more than 70) was. Conclusion: During the "waves" of the pandemic, radiation therapy (RT) was not administered to specific groups of cancer patients eligible for it because other medical departments for oncology patients were closed.
Trends in gynecologic oncology before and during COVID - 19 pandemic in Tuzla Canton
Authors: Serak Adnan
Published: August 2024

Aim: The aim of this study was to assess the impact of the COVID-19 pandemic and its management on the rate of newly diagnosed cancers from the perspective of a tertiary referral center in Tuzla Canton.Methods: All patients diagnosed with gynecological cancer at Department of Gynecology and Obstetrics, University Clinical Center Tuzla, in prepandemic, pandemic and postpandemic period, were presented in this study. Gynecological cancer was defined as one of the following diagnoses: ovarian or tubal carcinoma, cervical carcinoma, endometrial carcinoma, uterine sarcoma, vulvar carcinoma, vaginal carcinoma, and germ cell tumors.A total of 579 patients with newly diagnosed cancers were collected in 2020. There were 109 newly diagnosed gynecological cancers in 2020., while in 2019 there were 134, and 136 in 2021. Numbers of gynecological cancers diagnosed during pandemic were compared to numbers in prepandemic and postpandemic period. Results: There was a total of 579 patients with newly diagnosed cancer in Clinical Center of Tuzla during 2020. That showes strong decline of newly diagnosed cancers compared to 2019 with 1030 newly diagnosed cancers. Of these 579 patients, 109 presented in 2020 with newly diagnosed gynecological cancers. That shows strong decrease compared to 2019. with 134 newly diagnosed gynecological cancers and 2021 with 136 gynecological cancers. In 2019. 4015 PAP tests were examined, with only 1917 PAP tests examined in 2020 (diagram 4). In 2019. we did 199 HPV typisation test, while in 2020. there were only 34.Conclusion: The lockdown coused by COVID - 19 pandemic led to decreased number of routine examinations including annual PAP smear testing and HPV typisation tests. It also led to decrease number of other checkups. All of that led to decreased number of newly diagnosed gynecological cancers.
The role and importance of vitamin D in patients with Corona virus disesase (COVID-19)
Authors: Dizdarevic Hudic Larisa , Plavsic Dusica , Brkic Selmira , Numanovic Fatima , Hudic Igor , Suljic Zerina
Published: August 2024

Severe acute respiratory syndrome novel coronavirus (SARS-CoV-2) has rapidly progressed from an outbreak to a global pandemic, with new variants emerging rapidly. Coronavirus disease 2019 (COVID-19), a disease caused by SARS-CoV-2 infection, can lead to multiorgan damage. Due to the highly contagious and fatal nature of the virus, the priority of medical research has been to find effective treatments. Amid this search, the role of vitamin D in modulating various aspects of the innate and adaptive immune system has been debated.The aim of the work: research on the role of vitamin D in the treatment and prevention of COVID-19. Although there are some conflicting results, the consensus is that vitamin D has a number of immunomodulatory effects that may be beneficial in the context of COVID-19 and that low vitamin D levels may result in dysfunction of key antimicrobial effects, potentially contributing to a poor prognosis. The aim of the paper is to investigate the impact and importance of vitamin D in patients with the corona virus.Work methods: During this retrospective study, data were taken from the Registry of those tested for the presence of the SARS-CoV2 virus, Specialist Center "Health House" in Bijeljina. The research included 30 patients positive for the presence of the SARS-CoV2 virus and 30 patients negative for the presence of the SARS-CoV2 virus. The following parameters were observed in the research: age, gender and vitamin D values, data on the body temperature of the patients and the duration of the disease, as well as the obtained results of the inflammatory parameters (Leukocytes and C- reactive protein CRP). The dana of all patients are anonymous. All patients were tested using the molecular method of polymerase chain reaction known as RT-PCR (Reverse transcription polymerase chain reaction). Separate samples were tested with Arhitectt Vitamin D reagent by the chemiluminescence method (CMIA), manufactured by Abott Arhitectt and 1000sr. Reference values of Vitamin D are from 75 to 150 nmol/L.Results: The concentration of vitamin D was lower in the group of patients with the coronavirus disease (COVID-19) compared to individuals with the absence of the coronavirus disease. There is a tendency towards a negative correlation between the concentration of vitamin D and the duration of the disease in the group of patients with the coronavirus disease (COVID-19), as like as the concentration of vitamin D and body temperature in the group of patients with the coronavirus disease (COVID-19). There is also a tendency towards a negative relationship between the concentration of vitamin D and parameters of inflammation (CRP, Le) in the group of patients with coronavirus disease (COVID-19).
Hemolytic uremic syndrome in a Pediatric Intensive Care Unit- Rapid review with case series
Authors: Hadzic Devleta , Osmancevic Lejla , Zulic Evlijana , Atic Nedima , Mrsic Aida , Spahic Razija , Ibrelic Luna
Published: August 2024

Hemolytic uremic syndrome (HUS) is a multiorgan clinical syndrome characterized by the simultaneous occurrence of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. This is the most important form of thrombotic microangiopathies in children and is considered the main cause of acute renal insufficiency in children, especially under the age of five. Over 90% of HUS in children is associated with infection, and the prodromal manifestation most often includes bloody diarrhea. Atypical hemolytic uremic syndrome (aHUS) is a rare but progressive, life-threatening condition that affects about 10% of HUS cases in children. It is predominantly caused by dysregulation of the alternative complement pathway and genetic predisposition. Conditions that enhance complement, such as some viral infections, malignancies, autoimmune diseases and transplantation may be comorbid in up to 70% of aHUS cases. The 2016 International Hemolytic Uremic Syndrome Group classification, based on the etiology, separates 4 groups: caused by infection, with coexisting conditions, due to cobalamin C disorders and due to complement dysregulation. Monoclonal antibody that effectively blocks complement activation, has significantly changed aHUS treatment and outcome. Early etiological recognition in order to start specific treatment as soon as possible is crucial for the outcome. This paper, through a rapid review and series of three children treated for HUS in our pediatric intensive care unit over a two-year period, aims to emphasize the complexity of the diagnosis and treatment of HUS, and the importance of a multidisciplinary team in order to to avoid complications, and achieve the best short- and long-term outcome
Specific therapeutic methods in lumbar facet syndrome tratment: prliminary study
Authors: Adzemovic Rabija , Tupkovic Emir , Bijedic Elvir , Damadzic Dzenana , Suljagic Omar
Published: August 2024

Introduction: Specific therapeutic methods (STM) are manual techniques used to treat tissue blockade.Aim of this research is to determine efficacy of STM in treatment of lumbar facet syndrome (LFS).Patients and methods. The study included 60 patients suffering from LFS (65% women) aged ~47. The patients were treated ~24 days with the following 2-8 procedures: osteopathy, “myofascial release”, acupuncture, acupressure, “cupping”, neurodynamic, proprioceptive neuromuscular facilitation, kinesiotherapy, “kinesio-type taping”, homeopathy and electrotherapy. All patients were evaluated at admission and discharge through: a. pain scale with visual analogue scale (VAS) marked with numbers 1 to 10 (1 being state of no pain, 10 being state of maximum pain); b. disability with so-called Oswestry index (ODI) expressed in percentages (0-20% being minimum, 80-100% being complete disability); c. quality of sleep, rated through modified Pittsburgh index of sleep quality (PSQI) expressed between 0 (very poor) and 4 (very good). The assessment of improvement in pain intensity and level of disability was conducted via subtraction of values noted before treatment from values at the end of treatment, while the assessment of sleep quality improvement was conducted via subtraction of values noted at the end of treatment from the values noted before treatment. Non-parametric statistical analyses were used. Results: significantly lower values of VAS (p<0.0001) and ODI (p?0.0001), significant increase in PSQI (p?0.0001) at the end in relation to the beginning of treatment, as well as significant correlation between decrease in pain and disability (r=0.3292, p=0.0105). No significant difference in pain (p=0.9856) and disability (p=0.9171 decrease was noticed between sexes.Conclusion: STM is efficient in the treatment of pain attacks in patients of both sexes suffering from LBS.
Influence of Growth Temperature on Morphological and Structural Properties of Sputtered- Zinc Oxide Nanorods
Authors: Bao Quan Tran  , Hai Dang Ngo  , Thi Kim Hang Pham
Published: August 2024

Zinc oxide is highly sought after for several applications in biology, optoelectronics, electronics, and sensing. Zinc oxide nanorods exhibit a high exciton binding energy and a wide direct band gap, making them an attractive material for ultraviolet optoelectronic devices in the compound semiconductor field. This investigation focuses mainly on the influence of growing temperature on the crystal structure and surface morphology of ZnO nanorods, specifically for their application as UV photodetectors. Si (100) substrates were utilized for the growth of ZnO nanorods using radio frequency magnetron sputtering. The ZnO nanorods are grown at temperatures of 350 °C, 375 °C, and 400 °C, respectively. The crystal structure and surface morphology were examined using X-ray diffraction and scanning electron microscopy. The samples exhibited a same crystal orientation of the (002) diffraction peak at all growth temperatures. The growth temperatures show a direct influence on the density and length of nanorods, as evidenced by the scanning electron microscopy photographs. The results revealed the significant influence of substrate temperature on the regulation of nanorod length and crystal formation.
Thiết Kế Và Đánh Giá Thuật Toán Băm Bảo Mật SHA-256 Trên Nền Tảng Phần Cứng ZynQ-702
Authors: Thi Hong Hieu Nguyen  , Thi Anh Duong Tran  , Anh Duong Van  , Nhut Minh Ho  , Ngo Lam Nguyen  , Quang Phuc Truong
Published: August 2024

Hàm băm đóng vai trò quan trọng trong các hệ thống bảo mật, được sử dụng rộng rãi trong xác thực quyền riêng tư. Thuật toán băm là một thuật toán mã hóa có cấu trúc phức tạp, sử dụng nhiều phép biến đổi logic, biến đổi toán học bên trong. Do vậy khi triển khai thuật toán băm bằng phần mềm, CPU sẽ mất nhiều thời gian để tìm nạp lệnh dẫn tới tốc độ chậm và tiêu tốn tài nguyên máy tính. Hướng tiếp cận thực thi thuật toán băm trên phần cứng sẽ giúp tối ưu về tốc độ bởi phần cứng hoạt động xử lý song song. Có thể thiết kế hệ thống thuật toán băm như một chip ASIC với chức năng xác định tích hợp bên trong máy tính, song hướng thiết kế FPGA đem lại lợi ích về tính linh hoạt, có thể tái lập trình được. Trong bài báo này, chúng tôi thiết kế một hệ thống thực thi thuật toán băm bảo mật SHA-256 và đánh giá các thông số tài nguyên sử dụng, công suất hoạt động trên nền tảng phần cứng ZynQ-702. Chức năng của thuật toán được kiểm chứng thông qua mô phỏng dạng sóng sử dụng phần mềm Xilinx Vivado 2019.1.
Free Vibration of the Magneto-Electro-Elastic Plates Resting on Elastic Foundation Using the Refined Plate Theory with Two Variables
Authors: L. T. Phong  , T. Nguyen-Thanh  , N. A. Dat  , T. T. Trien  , P. T. Hung
Published: August 2024

The objective of this article is to investigate the free vibration analyses of the functionally graded magneto-electro-elastic (FG MEE) plates supported by an elastic foundation using the refined plate theory (RPT) with two variables. The elastic foundation is modeled utilizing the Winkler-Pasternak theory. The power-law model is employed to characterize the graded material properties of the FG MEE plates. According to the RPT and Hamilton's principle, the governing equations of the FG MEE plate are derived. The displacement fields and electric and magnetic potentials are approximated using the Non-Uniform Rational B-Splines (NURBS) basic functions of the isogeometric approach (IGA). The proposed model’s advantages and accuracy are demonstrated by comparing the obtained results with those reported in the existing literature. The study comprehensively examines and discusses the impact of several parameters, including the power index, initial external magnetic potential and electric voltage, and the geometry, on the vibration frequency of the FG MEE plates. The numerical findings indicate that an increase in the power index leads to a decrease in the frequency of the FG MEE plates. Besides, the stiffness of FG MEE plates decreases with an increase in the initial external electric voltage, whereas it increases with an increase in the initial external magnetic potential. This article presents valuable perspectives on examining vibration analysis of the FG MEE plates, which can inform the design of innovative materials and structures with customized properties.
Điều Khiển Mô Men Động Cơ Từ Trường Dọc Trục Nam Châm Vĩnh Cửu (AFPMSM) Tích Hợp Bánh Xe Bằng Thuật Toán Thích Nghi Mờ-Nơ Ron (ANFIS) Ứng dụng Cho Xe Ô Tô Điện
Authors: Duy Hoang Dao  , Trong Minh Tran  , Thanh Ha Vo
Published: August 2024

Bài báo này sẽ trình bày thiết kế của bộ điều khiển mô-men cho động cơ từ trường dọc trục đồng bộ nam châm vĩnh cửu (AFPMSM) tích hợp bánh xe dựa trên thuật toán thích nghi mờ-nơ ron (ANFIS). Đây là thuật toán mạng nơ ron gồm 5 lớp được huấn luyện dựa trên phương pháp mờ Takagi–Sugeno. Lớp thứ nhất (lớp vào) bao gồm các vector sai số và đạo hàm vector sai số của dòng điện stator. Lớp thứ hai là lớp mờ hoá có nhiệm vụ xác định chức năng của các vectơ đầu vào. Lớp thứ ba thực hiện tính toán hệ thống theo luật mờ với ma trận 5x5. Lớp thứ tư thực hiện giải mờ. Lớp cuối cùng sẽ đưa ra đáp ứng điện áp stator theo yêu cầu đến bộ nghịch lưu nguồn áp. Bộ điều khiển này có ưu điểm là thực hiện thiết kế đơn giản vì bộ điều khiển không phụ thuộc vào mô hình toán học động cơ. Bên cạnh đó, ANFIS thích nghi với nhiễu do thông số động cơ AFPMSM thay đổi, vì vậy ANFIS đã cải thiện được các đáp ứng dòng điện, mô-men, và nâng cao tính bền vững hệ truyền động xe ô tô điện so với bộ điều khiển PI truyền thống. Hiệu quả của giải pháp đề xuất được đánh giá, phân tích thông qua mô phỏng MATLAB/SIMULINK.
Preparation and Characterization of 1D, 2D, and 3D Shapes of Anisotropic Gold Nanoparticles
Authors: Trong Phat Huynh  , Hoang Trung Huynh  , Duc Trung Vu  , Dinh Tung Nguyen  , Thai Gia Phu Pham  , Thi Hong Tham Nguyen
Published: August 2024

In recent times, the scientific community has become interested in gold nanoparticles, namely in the anisotropic class. Based on their shapes, they fall into three categories: one-, two-, and three-dimensional. The synthesis and properties of three different anisotropic gold nanoparticle preparations - gold nanobipyramids (one-dimension, 1D), gold nanoprisms (two-dimension, 2D), and gold stars (three-dimension, 3D) - are shown in this research. Here, our group describes a chemical reduction method mediated by seeds. X-ray powder diffraction, transmission electron microscopy, scanning electron microscopy, and ultraviolet-visible spectroscopy were used to analyze the anisotropic gold nanoparticles. The average dimensions of the nanobipyramids were 64.27 ± 7.31 nm for length and 25.87 ± 2.56 nm for diameter, according to the data; the average dimensions of the gold nanoprisms and goldstars were 43.54 ± 5.61 nm and 31.35 ± 7.01 nm, respectively. Furthermore, following centrifugation purification, the yields of triangle and bipyramidal particles rose from 40% to over 60% and from 60% to 90%, respectively. It was established what the ideal parameter concentration was to create anisotropic gold nanoparticles in three dimensions: one, two, and three.
Meningkatkan Kemampuan Mengenal Warna Melalui Eksperimen Hujan Pelangi
Authors: Fatma  , Hidayatu Munawaroh
Published: August 2024

Mengenali konsep warna penting untuk mengembangkan kemampuan kognitif anak. Warna adalah sebuah konsep atau petunjuk yang mungkin muncul sebagai akibat dari pantulan cahaya atau zat, dan juga dapat menimbulkan kesan terhadap mata. Sayangnya kebanyakan anak masih bingung bahkan tidak mengetahui warna apa yang ia gunakan pada saat mewarnai atau ketika pendidik bertanya warna benda yang dipegang, anak hanya diam menunggu pendidik mengucapkannya terebih dahulu baru anak mengikutinya. Selain itu, terkadang anak merasa bosan ketika melakukan kegiatan mewarnai, karena biasanya mewarnai menjadi Langkah awal guru dalam mengenalkan warna kepada anak. Penelitian ini menggunakan pendekatan kualitatif deskriptif. Sampel pada penelitian ini adalah peserta didik di KB ‘Aisyiyah Ulil Albab. Penelitian ini bertujuan untuk memberikan pengalaman belajar baru bagi peserta didik mengenai pengenalan warna. Dengan adanya kegiatan eksperimen ini, diharapkan peserta didik mampu meningkatkan kemampuan seni dan kreativitasnya.
Doença de Crohn - uma revisão de literatura
Authors: Silveira Ana Paula de Oliveira , Gonçalves Bruno Peixoto , Carminate Camila Baquieti , Latorre Fernanda Ferradeira , Soares Gustavo Henrique de Oliveira , Aquino Isadora Porto de , Rodrigues Lara Santana , Rosa Laura de Oliveira Martins , Aguiar Leticia Juliana Pereira Costa , Couto Lucas Valente , Risson Mariana , Baptista Marcela Melo , Bastos Mariana Rodrigues Marinho de , Dorneles Stella Gontijo Sant’Anna Vaz de Melo , Leão Stephanie Sossi
Published: August 2024

A Doença de Crohn (DC) é uma condição inflamatória crônica do trato gastrointestinal, que pode afetar qualquer parte do tubo digestivo, mas é mais frequentemente encontrada no íleo e no cólon. A etiologia exata da DC permanece incerta, mas acredita-se que uma combinação de fatores genéticos, imunológicos e ambientais contribua para seu desenvolvimento. A doença é caracterizada por uma inflamação transmural, o que pode levar a complicações graves como estenoses, fístulas e abscessos. Este artigo fornece uma visão abrangente sobre a DC, cobrindo aspectos desde a epidemiologia até as estratégias de manejo. A prevalência da DC tem mostrado um aumento global, com uma incidência particularmente elevada em países desenvolvidos. A identificação precoce e a gestão adequada são essenciais para melhorar o prognóstico e a qualidade de vida dos pacientes. As estratégias de diagnóstico incluem exames endoscópicos, imagem por ressonância magnética e testes laboratoriais específicos. O tratamento envolve uma combinação de terapias medicamentosas e, em alguns casos, intervenções cirúrgicas. Recentemente, os avanços nas terapias biológicas têm proporcionado novas opções para pacientes com formas mais graves da doença. Os fatores prognósticos para a DC incluem a gravidade da inflamação, a presença de complicações e a resposta ao tratamento inicial. O acompanhamento contínuo é crucial para a gestão eficaz e para prevenir complicações a longo prazo, como câncer colorretal. As perspectivas futuras para a pesquisa incluem a identificação de novos biomarcadores, o desenvolvimento de terapias mais eficazes e a exploração de abordagens integradas para melhorar o manejo da doença. Este artigo revisa as abordagens atuais para o diagnóstico, tratamento e manejo da DC, destacando a importância de uma abordagem multidisciplinar e as inovações emergentes no campo.