bluuebunny/crossref_metadata_2025 huggingface dataset:
Transmissibility of Severe Acute Respiratory Syndrome Coronavirus 2 Among Household Contacts of Coronavirus Disease 2019-positive Patients: A Community-Based Study in India
Authors: Sreedevi Aswathy , Mohammed Ahmad , Satheesh Mini , UshaKumari Anuja , Kumar Anil , Raveendran Geetha , Narayanankutty Saritha , gopakumar Soumya , Rahman Anisur , David Sachin , Mathew Minu , Nair Prem
Published: April 2023

Background: The transmission of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is complex and multifactorial. We aimed to
identify the risk factors for infection among the household contacts of
index patients and to determine the incubation period, serial interval,
and estimates of secondary infection rate. Methods: We conducted a study
in three districts of Kerala among the inhabitants of households of
reverse transcriptase polymerase chain reaction (RT-PCR)-positive
coronavirus disease (COVID-19) patients between January and July 2021.
COVID-19-positive patients and corresponding contacts were enrolled and
followed up for 28 days to determine RT-PCR positivity and the presence
of total antibodies against SARS-CoV-2 on days 1, 7, 14, and 28 from the
date of enrolment. Results: The mean incubation period, serial interval,
and generation time were 1.6, 3, and 3.9 days, respectively. The
secondary infection rate was 43.0%. Individuals who worked outside the
home were protected, whereas those who had kissed the COVID-19-positive
patients during illness were more than twice at risk of infection than
those who had not kissed the COVID-19-positive patients. Similarly, the
contacts who had shared a toilet with the COVID-19-positive patients
were more at risk than those who had not shared a toilet. However, the
contacts who reported using masks were at a higher risk of infection in
household settings. Conclusions Assessment of SARS-CoV-2 transmission in
household settings is important, considering its high secondary
infection rate. Close physical contact and toilet sharing increase the
risk of infection. This study demonstrates shorter incubation period and
serial interval.
Polymorphonuclear myeloid-derived suppressor cells play a proinflammatory role via TNF-α + B cells through BAFF/BTK/NF-B signaling pathway in the pathogenesis of collagen-induced arthritis mice
Authors: Li Mei , Tang Zhicheng , Wu Haolin , Wang Yue , Chen Ziyan , cheng Zixue , Yan Xinyi , Zhao Nan , Tang Xiaojun , Zhang Huayong , Sun Lingyun
Published: April 2023

Objectives: Although various studies have been performed on the
function of polymorphonuclear myeloid-derived suppressor cells
(PMN-MDSCs) in RA, the results were conflicting. Here we were trying to
clarify the role of PMN-MDSCs in the pathogenesis of RA and its specific
mechanisms. Methods: We detected the frequencies and counts of
PMN-MDSCs, TNF- B cells, and Ki67
B cells in spleens and inflamed joints of
collagen-induced arthritis (CIA) mice using flow cytometry. The
pathological role of PMN-MDSCs was examined by anti-Ly6G neutralizing
antibodies against PMN-MDSCs or adoptive transfer of PMN-MDSCs. And the
modulation of PMN-MDSCs on B cells was conducted by coculture assays,
RNA-Seq, RT-qPCR, etc. The mechanism of BAFF regulating B cells was
verified through Western Blot and flow cytometry. Results:
PMN-MDSCs accumulated in the spleens and joints of CIA mice. PMN-MDSCs
depletion could alleviate the arthritis severity, which was accompanied
by decreased TNF- secretion and proliferation of B cells. And its
adoptive transfer also facilitated disease progress. Furthermore,
PMN-MDSCs from CIA mice had higher expression level of BAFF, which
regulated TNF- expression, proliferation and apoptosis of B cells
in vitro. What’s more, BAFF promoted phosphorylation of BTK/NF-B
signaling pathway. And Ibrutinib (BTK inhibitor) could reverse the
effect of BAFF on TNF- expression. Conclusions: Our study
suggested that PMN-MDSCs enhanced disease severity of CIA and
manipulated TNF- expression, proliferation and apoptosis of B cells via
BAFF, furthermore, BAFF promoted TNF- expression through BTK/NF-B
signaling pathway, which demonstrated a novel pathogenesis of PMN-MDSC
in CIA.
The influence of religious and worldview factors on the landscape design in Japan and China
Authors: Zychowska Maria , Chornomordenko Ivan , Kravchenko Iryna L. , Gnatiuk Liliia , Dmytrenko Andrii , Urakina Anastasiia , Smilka Vladyslav
Published: April 2023

The role of religious beliefs and philosophical teachings in the developmentof traditional landscape design principles and techniques is analyzed in thearticle. Examples for the analysis of this development were the traditional cultures of two countries of the Far East –Japan and China.In these cultures, animistic beliefs in the supernatural nature of the elements (sun, wind, thunder, rain, lightning), nature as such (worship of sacred trees, water, etc.) were organically combined with later Buddhist canons, which eventually led to the syncretism of religious and philosophical teachings –Buddhism,Taoism and Confucianismin China,Buddhism and Shinto –in Japan. The analysis was carried out on the material of traditional gardens most visited by tourists, which are positioned as typical examples of traditional landscape design in both countries.It is proved that the landscape design both inJapan and China developed according to principles similar to the development principles of other types of arts in these countries. In particular, Chinese landscape design was based on the harmonization and improvement of nature, aimed at creating a certain hedonistic space, on the other hand, Japanese landscape design had religious origins from the beginning and was aimed at self-improvement through the observation of nature.
Social media for communicating health information in Uganda: constraints and practical suggestions
Authors: Nakiwala Aisha Sembatya , Kakooza Fred
Published: April 2023

African countries are experiencing an upsurge in the use of new information communication technologies, particularly the mobile phone. Such technologies have accelerated the use of social media platforms, such as Facebook, as tools for information dissemination on all aspects of life. Despite their widely acknowledged role in accelerating access to information, the health sector in developing countries has been reluctant to adopt social media platforms to communicate health. Through in-depth interviews, this paper explores experiences of selected health promoting organisations in Uganda of using Facebook to connect people to health. Understanding opportunities and constraints to using social media platforms in communicating health as argued from the communicative affordances approach can potentially improve health outcomes through augmenting not just access to health information but care as well. Our findings show that among others, Facebook provides opportunity for multimedia communication and specific targeting for health messages. Its potential for health communication is however constrained by financial, structural and technological limitations prevailing in organizations. We recommend that instead of overlooking social media as tools for health information dissemination, focus should be directed to addressing barriers to their effective utilisation.
Utilization of waste plum stones as a source of oil and catalyst for biodiesel production
Authors: Miladinovic Marija , Pavlovic Stefan , Bankovic-Ilic Ivana , Kostic Milan , Stamenkovic Olivera , Veljkovic Vlada
Published: April 2023

Possibilities of using waste plum stones in biodiesel production were
investigated. The plum kernels were used as a source to obtain oil by the
Soxhlet extraction method, while the whole plum stones, the plum stone shells
that remained after the crashing, and the plum kernel cake that remained
after the oil extraction, were burned off to obtain ashes. The collected
ashes were characterized by elemental composition, porosity, and base
strength and tested for catalytic activity in transesterification of
esterified plum kernel oil. Dominant elements were potassium, calcium, and
magnesium at different contents in the three obtained ashes. The most active
catalyst was the plum stone shell ash, so the effect of temperature (40, 50,
and 60?C) on the reaction rate was investigated. The reaction rate constant
increased with the reaction temperature with the activation energy value of
58.8 kJ mol-1. In addition, the plum stone shell ash can be reused as a
catalyst after recalcination.
Long Noncoding RNA PPT2-EGFL8 Regulates Pathological Retinal Neovascularization in PDR by Functioning as a Competing Endogenous RNA
Authors: Xu Zifan , Yang Jiahui , Zheng Haohan , Xie Tianhua , Yang Qian , Cai Jiping , Sun Chao , Cao Yujuan , Wu Meili , Liu Yanqiu , Cui Yuqing , Yao Yong , Wang Xiaolu
Published: April 2023

Diabetic retinopathy (DR) is a common complication in patients with diabetes, and proliferative DR (PDR) has become an important cause of blindness; however, the mechanisms involved have not been fully elucidated. miRNAs and long noncoding RNAs can play an important role in DR, and they can accurately regulate the expression of target genes through a new regulatory model: competing endogenous RNAs. We isolated total RNA of extracellular vesicles (EVs) in the serum of healthy individuals and individuals with diabetes without DR, non-PDR, or PDR, and performed deep sequencing. We found aberrantly low expression of PPT2-EGFL8 and significantly increased level of miR-423-5p. PPT2-EGFL8 adsorbs miR-423-5p as a molecular sponge and inhibits hypoxia-induced human retinal microvascular endothelial cells proliferation. In an oxygen-induced retinopathy (OIR) model and a streptozotocin-induced diabetes model, Egfl8-overexpression treatment reduces diabetes-related reactive gliosis, inflammation, and acellular capillaries and attenuates the development of pathological neovascularization. In addition, PPT2-EGFL8 targeting miR-423-5p plays an important role in hypoxia-induced peroxisome proliferator-activated receptor-β/δ (PPARD)/angiopoietin-like 4 (ANGPTL4) signaling activation, especially the expression of the C-terminal ANGPTL4 fragment. Finally, ANGPTL4 significantly induces retinal vessel breakage in the inner limiting membrane and facilitates retinal vessel sprouting into the vitreous in the OIR mice. Thus, either new biomarkers or new therapeutic targets may be identified with translation of these findings.
Biallelic Mutations in P4HTM Cause Syndromic Obesity
Authors: Saeed Sadia , Ning Lijiao , Badreddine Alaa , Mirza Muhammad Usman , Boissel Mathilde , Khanam Roohia , Manzoor Jaida , Janjua Qasim M. , Khan Waqas I. , Toussaint Bénédicte , Vaillant Emmanuel , Amanzougarene Souhila , Derhourhi Mehdi , Trant John F. , Siegert Anna-Maria , Lam Brian Y.H. , Yeo Giles S.H. , Chabraoui Layachi , Touzani Asmae , Kulkarni Abhishek , Farooqi I. Sadaf , Bonnefond Amélie , Arslan Muhammad , Froguel Philippe
Published: April 2023

We previously demonstrated that 50% of children with obesity from consanguineous families from Pakistan carry pathogenic variants in known monogenic obesity genes. Here, we have discovered a novel monogenetic recessive form of severe childhood obesity using an in-house computational staged approach. The analysis included whole-exome sequencing data of 366 children with severe obesity, 1,000 individuals of the Pakistan Risk of Myocardial Infarction Study (PROMIS) study, and 200,000 participants of the UK Biobank to prioritize genes harboring rare homozygous variants with putative effect on human obesity. We identified five rare or novel homozygous missense mutations predicted deleterious in five consanguineous families in P4HTM encoding prolyl 4-hydroxylase transmembrane (P4H-TM). We further found two additional homozygous missense mutations in children with severe obesity of Indian and Moroccan origin. Molecular dynamics simulation suggested that these mutations destabilized the active conformation of the substrate binding domain. Most carriers also presented with hypotonia, cognitive impairment, and/or developmental delay. Three of the five probands died of pneumonia during the first 2 years of the follow-up. P4HTM deficiency is a novel form of syndromic obesity, affecting 1.5% of our children with obesity associated with high mortality. P4H-TM is a hypoxia-inducible factor that is necessary for survival and adaptation under oxygen deprivation, but the role of this pathway in energy homeostasis and obesity pathophysiology remains to be elucidated.
Health-related quality of life after segmental pedicle screw instrumentation: a matched comparison of patients with neuromuscular and adolescent idiopathic scoliosis
Authors: Soini Venla , Syvänen Johanna , Helenius Linda , Raitio Arimatias , Helenius Ilkka
Published: April 2023

Background and purpose: Progressive neuromuscular scoliosis (NMS) often requires a long instrumented spinal fusion to improve health-related quality of life (HRQoL) and sitting balance. Segmental pedicle screw instrumentation improves HRQoL in patients with adolescent idiopathic scoliosis (AIS), but data on NMS is limited. We aimed to assess the impact of spinal fusion on HRQoL in NMS patients.Patients and methods: We conducted a retrospective case-control study with prospective data collection of NMS patients undergoing posterior spinal fusion at a tertiary level hospital in 2009–2021. 2 controls with AIS matched for sex and age were selected for each NMS patient. The Scoliosis Research Society-24 (SRS-24) questionnaire was utilized for pre- and postoperative HRQoL assessment. Follow-up time was a minimum of 2 years.Results: 60 NMS and 120 AIS patients were included in the analysis, and the mean age (SD) at operation was 14.6 (2.7) in NMS and 15.7 (2.5) in AIS groups. Total SRS score and all domains showed a significant improvement in NMS patients (p < 0.05). Total SRS score improved more (p < 0.001), while pain score improved less (p = 0.04) in NMS (change [95% CI], 0.31 [0.05–0.58] and 0.55 [0.27–0.81]) compared with AIS (0.01 [–0.10 to 0.12] and 0.88 [0.74–1.03]). Postoperative self-image was significantly better in NMS than in AIS at 2-year follow up (p = 0.01). Pelvic instrumentation reduced improvements in the SRS domains.Conclusion: HRQoL in NMS patients improved significantly after spinal fusion, and these benefits are comparable to those of AIS patients.
Cost-effectiveness and Quality of Specialized and Routine Care in a German Cohort of Patients with Chronic Pruritus
Authors: Müller Svenja , Ständer Sonja , Naatz Mandy , Augustin Matthias , Steinke Sabine
Published: April 2023

Chronic pruritus is a prevalent interdisciplinary symptom with a strong influence on health-related quality of life. Patients need extensive diagnostics and long-term treatment. This retrospective and prospective cohort study compared routine and university-based specialized care in terms of cost-effectiveness and patient benefit. Direct medical and non-medical costs and patient-reported outcomes (PRO; pruritus intensity, quality of life, treatment needs and benefits) were assessed. Data analyses were conducted using descriptive methods and non-parametric statistical tests. A total of 300 adult patients (54.3% female) participated in the study. Six months after the treatment start in a specialized German pruritus care unit, the total costs were significantly reduced (mean total costs 686 € vs 433 € per patient per half year (total cohort); p <  0.001; mean out-of-pocket costs 198 € vs 124 € per half year (total cohort), p <  0.001). Pruritus intensity (numerical rating  scale 5.3 vs 3.7, p < 0.001), quality of life (Dermatology Life Quality Index 8.9 vs 5.7, p < 0.001) and patient benefit (Patient Benefit Index Pruritus 1.2 vs 2.1, p < 0.001) improved significantly (total  cohort). The results of this study show, that treatment of chronic pruritus patients in a specialized itch centre leads to an improvement in patient  benefit and reduces the economic burden at the same time.
The Treat-to-Target Project in Atopic Dermatitis: One Year On
Authors: De Bruin-Weller Marjolein , Deleuran Mette , Biedermann Tilo , Bissonnette Robert , Foley Peter , Girolomoni Giampiero , Hercogová Jana , Hong Chih-Ho , Katoh Norito , Pink Andrew , Richard Marie-Aleth , Shumack Stephen , Silvestre Juan Francisco , Thyssen Jacob P. , Weidinger Stephan
Published: April 2023

Atopic dermatitis is a chronic skin condition for which a range of systemic treatments have recently been approved. A treat-to-target strategy has been developed previously alongside an algorithm to guide the management of patients with atopic dermatitis. Here, we review the strategy and algorithm in the context of the evolving therapeutic landscape, and identify areas for further refinement and development.
Using psychological terms in different types of discourse by the examples of news corpus
Authors: Истомина Е.М.
Published: April 2023

В работе рассматривается употребление психологических терминов в непрофессиональных дискурсах с позиции типа интеракции, задействованных лингвистических механизмов и передаваемой оценки. Актуальность исследования обусловлена активным проникновением терминов психологии в различные типы дискурса: лексика, которая употреблялась изначально исключительно профессионалами при общении на профильные темы, прочно укрепилась в лексиконе людей, которые не связаны с психологией. Результаты исследования психологических терминов и механизмов их переносов в непрофессиональные дискурсы, проведенного на примере корпуса новостных статей, выявили, что: во-первых, самыми частотными являются термины с отрицательной оценкой, во-вторых, наблюдается отчетливая тенденция к переносу терминов в непрофессиональные дискурсы на основе метафоры с сохранением оценки.

The work deals with the psychological terms in non-professional discourses with regard to the type of interaction, linguistic devices engaged and evaluation expressed. The relevance of the research is caused by the active penetration of psychological terminology in different types of discourses. The vocabulary initially used exclusively by professionals while communicating on fieldspecific topics has firmly entered the lexicon of individuals not engaged in psychology. The findings from the research of the psychological terms and mechanisms for transferring them to nonprofessional discourses performed by the material of a news article corpus revealed that: firstly, the most frequent are terms with the negative evaluation; secondly, there is a clear tendency for metaphor-based transfer of the terms into non-professional discourses keeping evaluative components.
Level of Knowledge and its Associated Factors towards Acceptable Diet of 6-23 Months Old Children in Gimbichu Woreda, Ethiopia
Authors: TS Tuji
Published: April 2023

Background: The available data suggests that the rate for Minimum acceptable diet (MAD) is low across all regions worldwide. The level of mothers towards acceptable diet one of the key elements to feed their child. However, level of Knowledge and its associated factors towards acceptable diet among infants and children aged between 6 and 23 months living in study area is unknown. Objective: this study was aimed to assess the level of Knowledge and associated factors towards acceptable diet among infants and children aged between 6 and 23 months old children in Gimbichu Woreda, Oromia, Ethiopia, 2019. Methods: A descriptive community-based cross-sectional study was conducted among 782 mothers/caregivers paired with infants and children aged 6 to 23 months with a response rate of 97.1%, from March 12 to April 08, 2019. One-stage cluster sampling technique was employed. A structured pretested tool was used to collect the data. The binary logistic regression analysis was applied for levels of knowledge. All variables were transformed to multivariable logistic regression model irrespective of any transforming criteria to control the effects of confounder/s and to identify statistically significant variables. Finally, the variables which had independent correlations with level of the knowledge were identified on the basis of Adjusted Odds Ratio (AOR) and a p-value less than 0.05with 95%CI were claimed as statistically significant. Results: The proportion good knowledge of the mother towards practicing MAD was 52.4% (95% CI, [48.8, 56.0]). Fathers’ who have attended secondary and above (AOR=3.97, 95%CI (1.58,12.42), mothers attending PNC [AOR=7.24, 95% CI (4.34,14.4), husband involvement (AOR=6.05, 95% CI (2.43,15.10), richest wealth status [AOR=2.7, 95%CI (1.24,6.03), women’s involvement [AOR= 9.32, 95% CI (4.03,21.52) were positively associated with the level of knowledge. Conclusion: Almost half mothers have good knowledge regarding acceptable diet. Educational level of fathers, PNC, husband involvement, richest wealth status, and women’s involvement was positively associated with the level of knowledge. Assuring mother’s involvement on decision making and promoting husband involvement on infant and child feeding are strongly recommended to mitigate the problem.
Development of a New Product with a High Added Value: Biscuit with Carob Beans and/or with Oak Acorns Coffees
Authors: A Sami
Published: April 2023

Research on the development of carob and oak acorn recovery processes is very well developed today. Our research has resulted in the implementation of technologies for transforming carob and oak into various by-products such as; coffee production from carob beans and oak acorns. We have studied the physicochemical characteristics, nutritional, microbiological, biological activity and caffeine analysis of our samples of coffees produced from locust bean and oak acorn. Subsequently, these two coffees were integrated into the production of an organic biscuit in order to develop an innovative product with high added value. The results obtained show us that the sensory analysis has shown that the cookies have satisfactory organoleptic characteristics. The sensory analysis showed that the biscuit with the mixture of the two coffees has the highest percentage of appreciation by the tasting panel. Microbiological analysis showed that the cookies are free from coliforms, yeasts and molds. They contain a low level of total flora. Cookies can therefore be stored for a long time and could be sold as an important bio product for human health.
Consumers’ Perceptions of Bivalve Shellfish Quality and Safety among Niger Delta Population
Authors: SP Ukwo
Published: April 2023

Bivalve shellfish is a delicious and healthy diet in coastal cities around the world. They are important food items in several dietary regimes in the Niger delta. This study investigated consumers’ perceptions of quality and safety of bivalve shellfish among populations along Niger delta coastline. A clustered based sampling procedure was applied to carry out consumer survey on bivalve shellfish perceptions of quality and safety at four locations along the Atlantic coastline of Niger delta. This was carried out through the use open questionnaire administered through direct interview. Results showed a significant relationship (p<0.05) between some socio-economic attributes and perceptions toward bivalve shellfish consumption. A strong effects of these variables on perception towards bivalve was observed in mean scores of the determined variables. All bivalve species were adjudged to be easily available and cheap implying that bivalve shellfish is a low priced product. Bivalve consumers were conscious of the effects of environmental pollution on the product quality and safety but do not make it a pre-condition before purchasing the product. Over 22% of the consumers have experienced negative health related conditions such as stomach ache, diarrhea and vomiting which were attributed to bivalve consumption. The culinary tradition of consuming bivalve shellfish fresh or slightly cooked raised serious concerned about their safety and tendency to increase risks to consumers’ health. This survey would avail stakeholders in bivalve shellfish related businesses with adequate knowledge on the safety and possible source of risk to consumers
Long-Term Changes in Winter SST, Wind Stress and Anchovy Fishery in Relation to Climatic Indices along the South-Eastern Black Sea
Authors: Agirbas Ertugrul
Published: April 2023

A 47-year time series of winter Sea Surface Temperature (SST), wind stress and anchovy landing data from 1970 to 2016 was examined to assess long-term changes in these variables along the south-eastern coasts of the Black Sea in relation to the North Atlantic Oscillation (NAO), East Atlantic West Russia (EAWR) and Atlantic Multi-Decadal Oscillation (AMO) indices. An increase in winter SST at a rate of 0.02°C (r = 0.60; p<0.001) was observed over the period. Cumulative sums of the SST anomalies showed that there was a decrease in winter SST from 1985 to 1999, followed by an increase in SST from 2000 to 2014. Wind stress decreased throughout the time series, and it was inversely correlated with winter SST. Significant correlations detected between winter SST, wind stress, anchovy landings and winter values of the climate indices suggested that climate change is causing a decline in anchovy along the south-eastern coasts of the Black Sea.
Background Contribution to Assess the Trophic Water Conditions and Organic Components in Sediments at Santos and Cananeia Estuarine Systems-Brazil
Authors: Braga Elisabete de Santis
Published: April 2023

The dissolved inorganic compounds are normally used to identify the water quality of the coastal ecosystems. In the last decades, the dissolved organic compounds acquired a new dimension, in the water and in the sediments, due to its important role in the biogeochemical cycle of the organic matter. Concerning it, proteins, carbohydrates and lipids present on the sediments could be used in order to access the environmental trophic state. In this study, water properties and organic matter compounds in sediments were used in order to verify the trophic condition once it is a rare data from these regions. Although the PCA groupings are based on specific variables, such as water and sediment parameters, two specific groups were observed in both cases (a and b). Group a suggests stations with eutrophication tendency or, based on sediment variables, in hypertrophic condition, while Group b suggests areas in healthier conditions as meso-oligotrophic environments. Similarities on grouping based on water and sediment parameters were observed. The study of coupling water and sediment properties (pelagic and benthic coupling) and organic compounds constitute an important focus for improving the access to the trophic state avoiding the evaluation based only on sediment parameters that could cause more incertitude.
Self-Compassion as a Buffer against Eating Pathology in a Greek Community Sample
Authors: Eirini Karakasidou
Published: April 2023

The present study investigated the role of self-compassion (SC) in disordered eating and examined gender and age differences among the groups. Potential risk factors were also involved in the study, including gender, BMI, education status and exercise frequency. A total of a hundred participants (N = 100), equally distributed to two groups of males and females, were randomly selected across a Greek community sample. Participants completed questionnaires comprising the EAT-26, the SelfCompassion Scale (SCS) and PANAS Scale. Correlational analysis showed that SC is negatively associated with eating disorder symptomatology. SC and better eating attitudes relationship were stronger among older adults. Specifically, participants aged 24-29 and 30-35 presented higher SC scores and better eating attitudes, while there was no significant negative correlation for those aged 18-23. An independent samples t-test examining gender differences confirmed that females are more likely to be engaged in disordered eating behaviours than men. There were no statistically significant differences between the genders regarding their ability for SC. Multiple regression analysis indicated that biological and psychosocial factors such as gender, age, education, and BMI and exercise frequency did not predict disordered eating attitudes, while SC did. Regarding SC, multiple regression analysis found that education status, age, positive affect and EAT-26 scores all predicted SC scores. These findings suggest that SC may moderate disordered eating, thus being invaluable in designing and implementing prevention and intervention programs promoting better eating attitudes and well-being.
Understanding Consumers' Perception of Different Fish Species Marketed in Brazil using Word Association
Authors: Salim Ana Paula AA
Published: April 2023

Word association (WA) is a qualitative technique widely used to understand how consumers perceive food products. The aim of the present study was to investigate the consumer's perception (n = 300) regarding five different fish species marketed in Brazil and to elucidate whether the perception is affected by the consumption frequency using the WA task. Samples of the panga, tuna, salmon, tilapia, and hake were utilized in this study. Different perceptions were identified for both frequent and occasional fish consumers. Among 17 categories elicited to describe the fish species, almost all categories presented significant differences in the frequency of mention according to the chi-square per cell approach (p ≤.001). The conceptualization of each species of fish was strongly affected by the frequency of consumption of this matrix. The findings from the present work provided a insight into Brazilian consumers' perception of fish meat, which can be used to develop strategies to increase the commercialization of these species in the Brazilian market.
Effect of Ripening Stages and Drying Method on the Physico-chemical and Sensory Properties of Keitt Mango (Mangiferaindica L.) Sliced Chips
Authors: Techane Tolcha
Published: April 2023

Fruits (30-50%) harvested in developing countries does not reach consumer due to using inappropriate method of processing. The objective of this study was to investigate effect of ripening stage and drying methods on physicochemical and sensory properties of dried sliced mango chips. mango rich as sources of vitamins A, B and C and consumed for pleasant taste and flavor. This study was lied down with two factors on completely randomized design. Different drying methods (solar drying and oven drying) and ripening stage (unripe, intermediate and fully ripe) were evaluated for physicochemical quality. The effect of factors on properties determined by Analysis of variance and significance at (p <0.05). The data was collected from oven dry and solar drying with three replication and analyzed by using SAS software. The solar dried mangoes were evaluated for changes in moisture content (8, 8.83 and 9.83), ash content (3, 2.33 and 2.5), pH (4.02, 5.02 and 6.11), TSS (2.45, 2.83 and 3) rehydration capacity (50.83%, 63.93% and 58.65%), ascorbic acid (3.24, 1.82 and 1.47) and titratable acidity (0.05, 0.02 and 0.02) with unripe, intermediate and fully ripe mango respectively. The result showed that, for solar drying methods the best ripening stage was fully ripen. Other parameters also best for physicochemical qualities of solar-dried samples than ovendried samples. Generally, present study showed that, solar dried samples was the highest in rehydration capacity at unripe, intermediate, and fully ripen and higher in other physicochemical properties at ripening stage (unripe, intermediate, and fully ripen) compare with oven dried. However, because of some constraints, some parameters were not included. Therefore, based on the limitation of the work, further research is needed to study the effect of Ripening Stages and Drying Method on (vitamin (A and B) and minerals) and (protein, carbohydrates, fat), and betacarotien of mango fruits which are not conducted in this research due to budget and time limitations, large scale drying room needed.
The Main Natural Sources of Global Climate Variability Occurring Even Before the Industrial Era
Authors: Abayechaw Desta
Published: April 2023

Natural global climate variability and fluctuations are characteristic of the global climate and occur on both long- and shorttime scales as common phenomena. Therefore, natural influences on the global climate variability even before the industrial era may include changes in solar energy, naturally occurring water vapor and CO2 in the atmosphere, volcanic aerosol and GHG emissions, and cyclical oscillations in the oceans. However, natural variability and weather extremes, in particular local warming, influences people’s belief in climate change and their willingness to support potentially costly climate mitigation measures. Among natural sources of global climate variability, Volcanism has been a major driver of past climate variability by reflecting the incoming sunlight away from the Earth’s surface. According to different research finding, man-made climate variability in addition to natural global climate variability increase climate change from global to local level to be happen in below thirty years.
The Analysis Spoken Genre Across American and Indonesian Cultures Through Podcast: Joe Rogan and Deddy Corbuzier
Authors: Kalyana Putu Titha
Published: April 2023

Language, of course, is a tool of communication that cannot be divorced from daily activities. Speak genre analysis has resulted in a substantial number of studies on English in many genres like as presentations, speeches, interviews, and casual chats. Podcasting is an important emerging digital media that has long been used in education. As a result, it is necessary to evaluate whether the spoken genre in each country's podcast differs. This study aims to analyze the difference between cultures in Indonesia and America, especially in podcasts entertainment and to examine whether podcasts may impact discourse genres, mainly spoken genres across cultures, and was inspired by the applications and advantages of podcasts stated above and experimentally tested by various experts. This research uses descriptive qualitative research methods. The object of this research study is a conversation between two different podcasts, namely podcasts from Deddy Corbuzier and Joe Rogan. The practical aspect is the form of questions in every conversation between the two podcasts. The data source for this research is the YouTube channel account of Deddy Corbuzier and Joe Rogan. Data collection in this study was carried out using several techniques, including observation techniques, listening techniques and note-taking/writing techniques. Result showed there was a significant different between differences in language use, different types of questions, and speaking dominance between hosts and guest stars. Thus, the difference between spoken genres across Indonesia and America can be seen.
The Students’ Perception of Remote Teaching: An Analysis of Insufficient Parental Support on Academic Performance
Authors: I Gusti Ayu Md Denisha Vedhaswari
Published: April 2023

The COVID-19 pandemic has urged all the educational communities to transform that was once conventional learning into remote teaching, which has had a significant impact on students' academic performance. Previous observations has been conducted on factors that limited remote teaching. However, some students may perceive a lack of parental support, resulting in negative effects on their academic and emotional outcomes. This study aimed to analyze the impact of insufficient parental support on students' perception of remote teaching and academic performance. This study use a mixed-methods approach. The research respondents and source were only students in the twelve-grade majored in hospitality accommodation from one of the vocational schools.The data were collected with questionnaire and interviews, with purposive sampling technique. The results showed that among other factors of the limitation of remore teaching, the mean score of 3.18 indicated that the statement of students who did not receive sufficient parental support during remote teaching was the highest limiting factor in the remote teaching. Students perceive that when studying at home, if no parental support were present it became one of the barrier to for their academic achievement.
Chemotherapy and chemoembolization of patients with oncopathology as a risk factor for the development of myocardial dysfunction
Authors: Kubekova Saule , Zagorulya Natalya , Ryb Yelena , Malayev Niyaz , Abdilda Aruzhan
Published: April 2023

Considering the aging of the population, the combination of cardiovascular diseases with oncopathology is gaining more relevance. Liver cancer occupies the 6th place in the structure of the incidence of neoplasms and the 3rd place in mortality from all oncological diseases. One of the main methods of treating patients with liver cancer is chemotherapy and chemoembolization, which significantly affect the myocardium, developing cardiotoxicity. Myocardial damage is reflected in the development of heart failure, which subsequently is the main cause of death in cancer patients.
Evaluation of the relationship between vitamin D levels and emerge delirium in children who had tonsillectomy and/or adenoidectomy
Authors: Ümit Karacan Nagehan , Yılmaz Sinan , Yılmaz Mustafa
Published: April 2023

Background: Pediatric emergence delirium is a general complication of anesthesia with an incidence of 2-80%. Although its etiology is not clearly known, it has been shown that anesthesia method, surgical procedure, and child and parent anxiety may cause the emergence delirium. The relationship between vitamin D levels and emerge delirium in children who underwent tonsillectomy and/or adenoidectomy has not been investigated before

Aim:  In this context, this study was carried out to evaluate the relationship between vitamin D levels and emerge delirium in children who underwent tonsillectomy and/or adenoidectomy.

Material and methods: The study population consisted of children between the ages of 2 and 10, ASA I-II and were scheduled to have elective adenoidectomy and/or tonsillectomy under general anesthesia. All children (n=97) were evaluated for anxiety with the modified Yale Preoperative Anxiety Scale (m-YPAS) before surgery. Children with serum 25(OH)D levels<12 ng/ml and ≥12 ng/ml were categorized as group 1 (n=50) and group 2 (n=47). All children were evaluated for delirium with the Pediatric Anesthesia Emergence Delirium (PAED) scale. The face, legs, activity, cry, consolability (FLACC) scale was used in the evaluation of postoperative pain in children who could not express themselves verbally.

Results: The mean serum 1.25(OH)2D3 level was higher, albeit insignificantly, in group 1 than in group 2. There was no significant difference between the two groups in terms of emerge delirium, preoperative anxiety, postoperative pain and analgesia.

Conclusion: Vitamin D deficiency does not affect the incidence of emergence delirium in children. Vitamin D level does not relate to preoperative anxiety and postoperative pain.
The effect of therapeutic plasma exchange and intravenous immunoglobulin therapy on biomarkers and 28-day mortality in patients with COVID-19 in intensive care unit
Authors: Ökmen Korgün , Demirel Asiye , Ceylan İlkay
Published: April 2023

Background: The aim of our study was to determine the effectiveness of the co-administration of therapeutic plasma exchange and intravenous immunoglobulin therapy in intensive care patients with COVID-19.

Material and methods: In the propensity-matched study 46 patients were evaluated. The groups were defined as patients who received plasmapheresis + IVIg and standard treatment, and patients who received only standard treatment. The primary outcome of the study was determined as a 28-day mortality rate. Secondary outcome measures; demographic data were biomarkers of inflammation at admission and treatment days.

Results: In the evaluation of 23 patients in 2 groups, no statistically significant difference was found between demographic data, vital and respiratory status, additional diseases and treatments applied (p>0.05) .There was no difference in 28-day mortality rates between the two groups (p:0.688). CRP, IL-6 and Ferritin Lymphocytes values in the TPE+IVIg group were lower when compared to the control group in the values measured after the treatment (p<0.05). All inflammatory markers applied in the Cox regression model were associated with survival and no association was found.

Conclusion: In the results of this study, in which we applied TPE and IVIg treatment in combination, it was determined that this treatment method did not provide an additional benefit to the standard treatment. More clear information can be obtained by testing treatment applications in different doses and regimens and by randomized controlled studies.
Study on dynamic response characteristics of radial steel gate under rare earthquake considering fluid structure coupling effect
Authors: Shi S. , Han Y. , Hu K. , Zhou Y. , Hu T. , Lou Y. , Wang J. , Hou T.
Published: April 2023

The water resources in southwest China is abundant and the seismicity is strong, so it is necessary to study the dynamic response and safety of hydraulic structures under rare earthquake. Taking a typical radial steel gate as an example, a three-dimensional numerical model considering the interaction between water and gate during the earthquake is established. The accuracy and applicability of the model are verified by comparing with the measured results of the dynamic response of Zipingpu dam during the Wenchuan earthquake. Thereafter, the dynamic displacement and stress, and resonance frequency of the radial gate under the rare earthquake of two wave types are analyzed. The water-structure coupling effect has a great influence on the seismic dynamic response of the radial steel gate. The calculated result of the dynamic response of the gate considering the fluid-structure coupling effect is significantly larger than that of the specification, and the maximum ratio of the two is more than 2.27 times. Under the action of EI wave, the peak value of dynamic stress response is at the bottom of the panel, and the maximum value of resonance frequency (about49.13 Hz) is located in the middle and lower part of the panel. Under the action of far-field wave, the peak area of dynamic displacement response of the gate is basically the same as that under the action of EI wave, while the maximum value of some measuring points is only half of the maximum value under the action of EI wave. However, the resonance frequency is significantly greater than that of EI wave, the maximum value reaches 65.24 Hz, which appears at the top of the gate. The dynamic response of the gate structure caused by two different wave types of earthquakes is not completely consistent. The comprehensive consideration of different wave types is of significance for the structural design and safety evaluation of the radial steel gate in the earthquake-prone areas.
A Língua de Herança em contexto não-formal de aprendizagem: o caso da transmissão intergeracional do Português
Authors: Costa Wätzold Juliane
Published: April 2023

O aprendizado do Português como Língua de Herança em contextos não-formais de ensino implica diferentes desafios didático-pedagógicos, demandando investimento familiar. Ancorado em teorias ecológicas e sistêmicas, este volume apresenta um estudo de caso com abordagem etnográfica realizado na Baviera. A autora elucida como as dinâmicas intergeracionais que visam a transmissão e manutenção da Língua de Herança (centradas no uso da literatura infantil) contribuem para a construção da identidade cultural e linguística dos aprendentes e investiga os efeitos e o valor pedagógico dessas práticas.
НЕСИМЕТРИЧНІСТЬ ТЕРМІНІВ «МОВА ВОРОЖНЕЧІ» І «HATE SPEECH» ЯК ПРОБЛЕМА УКРАЇНСЬКОЇ МЕДІАТЕОРІЇ
Authors: Шeбештян Ярослава , Шаповалова Галина
Published: April 2023

У статті йдеться про проблему некоректності терміна «мова ворожнечі», популярного в сучасних жур­налістикознавчих дослідженнях; із урахуванням вимог щодо конструювання й використання терміноодиниць зроблено пропозиції альтернативних варіантів окреслення нетолерантних висловлень у мас­-медіа.
НОВИЙ ФРАЗЕОЛОГІЧНИЙ СЛОВНИК ІЗ ПОДІЛЛЯ*
Authors: Вовченко Галина
Published: April 2023

Рецензія
ДОЛЯ ПОСТУПИЛАСЯ*
Authors: Папіш Віталія
Published: April 2023

Рецензія
ДО ЮВІЛЕЮ ПРОФЕСОРА ІВАНА САБАДОША
Authors: Харьківська Олеся
Published: April 2023

Ювілеї
ПІДХОДИ ДО ВИВЧЕННЯ ІДІОМАТИКИ ТА ФРАЗЕОЛОГІЇ
Authors: Мосейчук Олександр , Усова Ірина
Published: April 2023

Дослідження спрямоване на виявлення основних підходів до вивчення ідіоматики та фразеології, інтеграція яких дозволяє сформувати всебічне бачення досліджуваного об’єкта. У межах структурно­-семантичного підходу фразеологізм та ідіома тлумачаться як усталене словосполучення, актуальне значення якого не виводиться зі значень його складових. Доведено, що ідіоми є носіями іллокутивної сили висловлення, виконують певні дискурсивні стратегії та спрямовані на досягнення певного перлокутивного ефекту
ПРО ФУНКЦІЇ УРБАНОНІМІВ
Authors: Негер Оксана
Published: April 2023

У статті вперше подано детальний аналіз функцій урбанонімів; розглянуто наявні загальноприйняті концепції; з’ясовано специфіку функцій урбанонімів у контексті функціонування топонімів; виділено основні (номіна­тивну і характеристичну) та факультативні (ідеологічну й асоціативну) функції
МОВНИЙ ПСИХОСВІТ ПРОГРАНОЇ БИТВИ (НА МАТЕРІАЛІ НОВЕЛИ О. КОБИЛЯНСЬКОЇ «БИТВА»)
Authors: Папіш Віталія
Published: April 2023

Стаття написана у психолінгвістичному ключі й спрямована на аналіз прихованих психологічних рис у художньому мовленні. Детально представлено мовні засоби реалізації авторської депресії на матеріалі новели О. Ко­ билянської «Битва» (1896 р.). Встановлено кореляційні зв’язки між лінгвістичними та психологічними параметрами творчої особистості. Основні висновки зводяться до того, що художнє мовлення – явище не тільки художнє, але й психологічне.
ПЕРЕОСМИСЛЕННЯ ЗНАЧЕНЬ СЛІВ ЯК ДЖЕРЕЛО ПОПОВНЕННЯ ЛЕКСИКИ ТРАДИЦІЙНОГО ТРАНСПОРТУ ТА КОМУНІКАЦІЙ В УКРАЇНСЬКИХ ГОВІРКАХ ЗАКАРПАТТЯ
Authors: Шкурко Галина
Published: April 2023

У статті розглянуто семантичні процеси у лексиці традиційного транспорту та комунікацій в українських говірках Закарпаття. Серед активних процесів, що виявлені у процесі дослідження лексичного складу лексико-семантичної групи, виділено метафоризацію, метонімізацію та інші трансформаційні процеси у межах семеми (зміщення, розширення, звуження, термінологізація, детермінологізація значень). Унаслідок проведеного наукового аналізу авторка доходить висновку про те, що семантичні процеси ведуть до утворення нових значень слів та сприяють активізації можливостей, закладених у самій системі зазначеної лексико-семантичної групи.
ВІДТВОРЕННЯ МЕНТАЛЬНИХ ОСОБЛИВОСТЕЙ УКРАЇНЦІВ У ФРАЗЕМІЦІ ТВОРІВ МИРОСЛАВА ДОЧИНЦЯ
Authors: Яцьків Марія
Published: April 2023

У статті розглянуто особливості використання загальновживаних та діалектних фразем у художніх творах сучасного закарпатоукраїнського письменника Мирослава Дочинця. У лінгвокультурологічному аспекті здійснено аналіз тематичної групи фразеологізмів на позначення розумової діяльності людини, а також з’ясовано їх роль і місце в індивідуальному стилі письменника.
МАЛА ПРОЗА УКРАЇНСЬКИХ ПИСЬМЕННИКІВ-ШІСТДЕСЯТНИКІВ У ПЕРЕКЛАДІ УГОРСЬКОЮ МОВОЮ
Authors: Балла Евеліна
Published: April 2023

У статті досліджено переклади угорською мовою зразків української малої прози письменників-шістдесятників, представлених в антологіях «Ukrán elbeszélők» («Українські оповідачі») (1968) та «Napraforgók. Mai ukrán elbeszélések» («Соняшники. Сучасні українські оповідання») (1982). Зроблено аналіз окремих художніх текстів (творів В. Дрозда, Гр. Тютюнника, Є. Гуцала, В. Шевчука, Р. Іваничука), що демонструють широту тематичної та стильової палітри тогочасної української новелістики, а також творчу еволюцію окремих митців. Наголошено на винятковій ролі упорядника та перекладача Шари Каріґ у популяризації української літератури. Предметом вивчення стали також досягнення в галузі перекладу Пала Мішлеї, Ендре та Анни Бойтарів, Єви Ґріґаші, Дьєрдя Радо та ін. Усі проаналізовані переклади засвідчують майстерність перекладачів, їх здатність адекватно передати засобами іншої мови зміст та художню специфіку текстів, різних за характером художнього вислову.