bluuebunny/crossref_metadata_2025 huggingface dataset:
Extracting Pole Characteristics of Complex Radar Targets for the Aircraft in Resonance Region Using RMSPSO_ARMA
Authors: Zhou Sang , Gao Huotao , Ren Fangyu
Published: May 2024

The extraction algorithm of target characteristics resonance set at the high-frequency band plays a significant role in defense applications like early warning. The paper proposes a new method to extract the characteristic resonance set of radar targets in the resonance frequency region using an autoregressive moving average model optimized by root mean square propagation particle swarm optimization. Considering that the total scattering response in the resonant region consists of early-time and late-time responses, the autoregressive moving average model approximate the total scattering responses to avoid errors caused by intercepting the late-time response. Further, the paper investigated the impact of the swarm optimization algorithm on the accuracy of moving average model parameters when obtaining the resonance set at different target aspects. The extracted characteristic resonance results within a range of azimuth directions through an aircraft target paradigm indicate that the new method is more convenient and precise than the matrix beam prediction method.
Modelling and Output Power Estimation of a Combined Gas Plant and a Combined Cycle Plant Using an Artificial Neural Network Approach
Authors: Xezonakis Vasileios , Samuel Olusegun David , Enweremadu Christopher Chintua
Published: May 2024

Artificial neural networks (ANNs) have gained prominence among contemporary computing techniques due to their capacity to handle complicated stochastic datasets and nonlinear modelling in combined gas and combined cycle power (COGAS) plants. Researchers, academicians, and stakeholders have been unable to predict, ensure effective operation, and prevent power outages in COGAS due to the nonlinearity. The first implementation of the simultaneous adoption of three types of ANNs using Levenberg–Marquardt (LM), Bayesian regularisation (BR), and scaled conjugate gradient (SCG) configurations for training and assessing a combined cycle power plant output is presented. The dataset used in this research is a 9568‐unit full combined cycle power plant basis load dataset, accessible through the public UCI Machine Learning Repository. It incorporates ambient temperature, exhaust vacuum, ambient pressure, and relative humidity as input parameters to predict the electric output power. The most accurate and dependable electric power predictions could be identified for 70% of the total data, of which 6698 were trained, 15% were tested, and 15% were validated (2870). By using the three training techniques, namely, LM, BR, and SCG, the parameterized networks are studied, increasing the number of hidden layers from 20 to 500. The lowest root‐mean‐square error value for a multilayer perceptron (MLP) architecture is 3.631%, which is lower than the values of 4.17%, 4.35%, and 4.63% for comparable MLP structures (20 to 500), documented in the literature. The LM and BR algorithms outperform SCG. These adopted algorithms could be a cutting‐edge application in the power plant industry and other real‐world applications for reliable solutions, to satisfy emerging societal needs with environmental benefits.
Persistent Lactatemia in Mauriac Syndrome
Authors: El Tobgy Nada , Hinz Laura
Published: May 2024

Mauriac syndrome is a rare disorder that occurs in patients with type 1 diabetes mellitus (T1DM) with glucose levels significantly above target, characterized by hepatomegaly, growth delay, and cushingoid features. Another distinguishing feature of Mauriac syndrome is persistent lactatemia during diabetic ketoacidosis (DKA) management. We present a case of an 18-year-old patient with T1DM who presented in DKA and then developed elevated lactate levels leading to a diagnosis of Mauriac syndrome. The cause of the persistent lactatemia is not well understood though it is likely related to glycogenic hepatopathy causing hepatomegaly, abnormalities in glucose metabolism, and subsequent inappropriate lactate production. Since the liver changes seen in Mauriac syndrome are reversible with optimal blood glucose control, these patients should be connected to intensive psychosocial and medical support to help them improve their blood glucose levels.
Modelo Pedagógico de la Administración Estratégica Parte 1. Presentación del Modelo
Authors: Geldes Cristián , Muñoz-Cisternas Victor , Castillo-Vergara Mauricio
Published: May 2024

Frente a los creciente desafíos que enfrentan las empresas para su desarrollo y sostenibilidad, se hace necesario que se administren desde una perspectiva estratégica, colocando sus esfuerzos en comprender su entorno para lograr una mejor posición competitiva basada en sus recursos y capacidades. En este marco, el artículo propone un modelo para facilitar la enseñanza y entendimiento de los conceptos, etapas y componentes claves de la gestión estratégica de empresas. Este modelo pedagógico considera que la gestión estratégica se realiza en dos etapas con sus componentes, como son la formulación de la estrategia y la implementación y control estratégico. Este artículo, tiene por objetivo presentar el modelo pedagógico que será complementado con otros artículos relacionados.
Análisis del Estado del Arte y Gestión de la Infraestructura Escolar en Chile: Desafíos y Perspectivas
Authors: Barrientos Oradini Nicolás
Published: May 2024

La gestión de la infraestructura escolar es un aspecto fundamental para el desarrollo educativo de cualquier país. En el caso de Chile, que ha experimentado transformaciones significativas en su sistema educativo en las últimas décadas, la adecuada administración de sus instalaciones escolares se presenta como un desafío crucial.(seguir leyendo...)
Obesidad y Sobrepeso Infantil: Un drama latente
Authors: Crespo Fernando A.
Published: May 2024

El año escolar para nuestro país comienza en marzo, y con ello preocupaciones que nos relacionan con el estudio, la educación, los colegios, y con otra problemáticas. Sin embargo, un tema pendiente tiene que ver con el componente de la salud física, y su íntima relación con los desempeños y bienestar particular que esta tiene, principalmente respecto de los índices de sobrepeso y obesidad de nuestros niños y niñas.(seguir leyendo...)
TABLE 6 from Stay on Track: A Pilot Randomized Control Trial on the Feasibility of a Diet and Exercise Intervention in Patients with Breast Cancer Receiving Radiotherapy
Authors: SenthilKumar Gopika , Schottstaedt Aronne M. , Peterson Lindsay L. , Pedersen Lauren N. , Chitambar Christopher R. , Vistocky Alexis , Banerjee Anjishnu , Longo John M. , Kelly Tracy , Currey Adam , Stolley Melinda R. , Bergom Carmen
Published: May 2024

Comparisons of nutritional outcomes at baseline, 3 months, and 6 months
TABLE 5 from Stay on Track: A Pilot Randomized Control Trial on the Feasibility of a Diet and Exercise Intervention in Patients with Breast Cancer Receiving Radiotherapy
Authors: SenthilKumar Gopika , Schottstaedt Aronne M. , Peterson Lindsay L. , Pedersen Lauren N. , Chitambar Christopher R. , Vistocky Alexis , Banerjee Anjishnu , Longo John M. , Kelly Tracy , Currey Adam , Stolley Melinda R. , Bergom Carmen
Published: May 2024

Comparisons of cytokine levels at baseline, 3 months, and 6 months
TABLE 3 from Stay on Track: A Pilot Randomized Control Trial on the Feasibility of a Diet and Exercise Intervention in Patients with Breast Cancer Receiving Radiotherapy
Authors: SenthilKumar Gopika , Schottstaedt Aronne M. , Peterson Lindsay L. , Pedersen Lauren N. , Chitambar Christopher R. , Vistocky Alexis , Banerjee Anjishnu , Longo John M. , Kelly Tracy , Currey Adam , Stolley Melinda R. , Bergom Carmen
Published: May 2024

Body composition and DEXA scan analysis at baseline, 3 months, and 6 months
Pharmaceutical Polygon Fingerprinting Matrix System: A Potential Tool for Pharmaceutical Quality Control
Authors: Elamrawy Fatema , Helal Nada A. , Abou-Taleb Basant A. , Elagouri Ghada , Vattelana Olivia , Nounou Mohamed I.
Published: May 2024

Background: We describe a new discriminatory system for evaluating the quality of pharmaceuticals, the Pharmaceutical Polygon Fingerprint Matrix system (PharmP-FM). PharmP-FM uses both qualitative and quantitative fingerprinting techniques to assess the quality of pharmaceutical formulations and dosage forms, the system expands on the Expert System for Drug Development, which was initially created to evaluate the suitability of powder for direct compression. PharmP-FM creates a graphical representation of the product’s pharmaceutical quality using a set of input parameters. The performance index (PI), normalized parameter index (NPI), and formulation index (FI) are among the system's output parameters. The objective of this study was to evaluate the performance of PharmP-FM by examining its ability to identify variations in pharmaceutical quality across products. Methodology: We examined the application of PharmP-FM in assessing batch-to-batch variability of weight-loss supplement capsules and the quality of multisource brand products of levothyroxine tablets. Results: PharmP-FM exhibits potential promise as a pharmaceutical quality assessment tool. Its user-friendly nature and adaptability to different formulations and dosage forms make it a versatile discriminatory system. Additionally, PharmP-FM is an open-ended and scalable system that can incorporate additional parameters and accommodate products of varying complexities. Conclusion: This study supports the potential of PharmP-FM as a tool for pharmaceutical quality assessment.
Efficacy of Combinational Treatment versus Nicotinamide Monotherapy in the Prevention of Ultraviolet Radiation-Induced Skin Cancer
Authors: Pihl Celina , Andersen Flemming , Bjerring Peter , Haedersdal Merete , Lerche Catharina Margrethe
Published: May 2024

Introduction: Ultraviolet radiation (UVR) is the primary risk factor for keratinocyte carcinomas. Oral supplementation with nicotinamide (NAM) is reported to reduce the formation of new keratinocyte carcinomas. NAM’s photoprotection is mediated by enhanced DNA repair. We wanted to explore whether NAM in combination with antiproliferative (metformin [Met]) or antioxidant (phloroglucinol [PG]) compounds could potentially enhance its photoprotective effects. Methods: Hairless mice (C3.Cg-Hrhr/TifBomTac) were treated orally with either a standard dose of NAM monotherapy (NAM-mono; 600 mg/kg) or NAM (400 mg/kg) combined with Met (200 mg/kg) (NAM-Met) or PG (75 mg/kg) (NAM-PG). Mice were irradiated with 3.5 standard erythema doses of UVR three times per week to induce tumour development. Photoprotective effects were based on (i) tumour onset of the first three tumours, (ii) skin photodamage, and (iii) DNA damage (cyclobutane pyrimidine dimers [CPDs] and pyrimidine-pyrimidone (6–4) photoproducts [6-4PPs]). Results: All mice treated with NAM demonstrated a delay in tumour onset and reduced tumour burden compared to the UV control group (NAM, NAM-Met, NAM-PG vs. UV control: p ≤ 0.015). NAM-mono and NAM-PG increased time until all three tumours with no difference between them, indicating a similar degree of photoprotection. NAM-mono had no effect on DNA damage compared to the UV control group (p > 0.05), whereas NAM-PG reduced 6-4PP lesions (p < 0.01) but not CPDs (p > 0.05) compared to NAM-mono. NAM-Met delayed the onset of the third tumour compared to the UV control but demonstrated a quicker onset compared to NAM-mono, suggesting inferior photoprotection compared to nicotinamide monotherapy. Conclusion: NAM-PG was as effective in delaying UVR-induced tumour onset as NAM-mono. The reduction in 6-4PP lesions may indicate that the mechanism of NAM-PG is better suited for photoprotection than NAM-mono. NAM-mono was superior to NAM-Met, indicating a dose dependency of NAM’s photoprotection. These results highlight the potential for combining photoprotective compounds to enhance photoprotection.
Uncovering Predictors of Low Hippocampal Volume: Evidence from a Large-Scale Machine-Learning-Based Study in the UK Biobank
Authors: Yeshaw Yigizie , Madakkatel Iqbal , Mulugeta Anwar , Lumsden Amanda , Hyppönen Elina
Published: May 2024

Introduction: Hippocampal atrophy is an established biomarker for conversion from the normal ageing process to developing cognitive impairment and dementia. This study used a novel hypothesis-free machine-learning approach, to uncover potential risk factors of lower hippocampal volume using information from the world’s largest brain imaging study. Methods: A combination of machine learning and conventional statistical methods were used to identify predictors of low hippocampal volume. We run gradient boosting decision tree modelling including 2,891 input features measured before magnetic resonance imaging assessments (median 9.2 years, range 4.2–13.8 years) using data from 42,152 dementia-free UK Biobank participants. Logistic regression analyses were run on 87 factors identified as important for prediction based on Shapley values. False discovery rate-adjusted p value <0.05 was used to declare statistical significance. Results: Older age, male sex, greater height, and whole-body fat-free mass were the main predictors of low hippocampal volume with the model also identifying associations with lung function and lifestyle factors including smoking, physical activity, and coffee intake (corrected p < 0.05 for all). Red blood cell count and several red blood cell indices such as haemoglobin concentration, mean corpuscular haemoglobin, mean corpuscular volume, mean reticulocyte volume, mean sphered cell volume, and red blood cell distribution width were among many biomarkers associated with low hippocampal volume. Conclusion: Lifestyles, physical measures, and biomarkers may affect hippocampal volume, with many of the characteristics potentially reflecting oxygen supply to the brain. Further studies are required to establish causality and clinical relevance of these findings.
Sex-Dependent Differences in the Neural Correlates of Cocaine and Emotional Cue-Reactivity in Regular Cocaine Users and Non-Drug-Using Controls: Understanding the Role of Duration and Severity of Use
Authors: Tap Stephan , van Stipriaan Eila , Goudriaan Anna E. , Kaag Anne Marije
Published: May 2024

Introduction: The development of cocaine use disorder in females is suggested to be more strongly related to neural mechanisms underlying stress-reactivity, whereas in males it is suggested to be more strongly related to neural mechanisms underlying drug cue-reactivity. Existing evidence, however, is based on neuroimaging studies that either lack a control group and/or have very small sample sizes that do not allow to investigate sex differences. Methods: The main objective of the current study was to investigate sex differences in the neural correlates of cocaine and negative emotional cue-reactivity within high-risk intranasal cocaine users (CUs: 31 males and 26 females) and non-cocaine-using controls (non-CUs: 28 males and 26 females). A region of interest (ROI) analysis was applied to test for the main and interaction effects of group, sex, and stimulus type (cocaine cues vs. neutral cocaine cues and negative emotional cues vs. neutral emotional cues) on activity in the dorsal striatum, ventral striatum (VS), amygdala, and dorsal anterior cingulate cortex (dACC). Results: There were no significant sex or group differences in cocaine cue-reactivity in any of the ROIs. Results did reveal significant emotional cue-reactivity in the amygdala and VS, but these effects were not moderated by group or sex. Exploratory analyses demonstrated that emotional cue-induced activation of the dACC and VS was negatively associated with years of regular cocaine use in female CUs, while this relationship was absent in male CUs. Conclusions: While speculative, the sex-specific associations between years of regular use and emotional cue-reactivity in the dACC and VS suggest that, with longer years of use, female CUs become less sensitive to aversive stimuli, including the negative consequences of cocaine use, which could account for the observed “telescoping effect” in female CUs.
Genotypic and Phenotypic Characterization of a Cohort of Patients Affected by Rod Cyclic Nucleotide Channel-Associated Retinitis Pigmentosa
Authors: Colombo Leonardo , Bonetti Gabriele , Maltese Paolo Enrico , Iarossi Giancarlo , Ziccardi Lucia , Fogagnolo Paolo , De Ruvo Valentino , Murro Vittoria , Giorgio Dario , Falsini Benedetto , Placidi Giorgio , Martella Salvatore , Galantin Eleonora , Bertelli Matteo , Rossetti Luca
Published: May 2024

Introduction: Retinitis pigmentosa (RP), a heterogeneous inherited retinal disorder causing gradual vision loss, affects over 1 million people worldwide. Pathogenic variants in CNGA1 and CNGB1 genes, respectively, accounting for 1% and 4% of cases, impact the cyclic nucleotide-gated channel in rod photoreceptor cells. The aim of this study was to describe and compare genotypic and clinical characteristics of a cohort of patients with CNGA1- or CNGB1-related RP and to explore potential genotype-phenotype correlations. Methods: The following data from patients with CNGA1- or CNGB1-related RP, followed in five Italian inherited retinal degenerations services, were retrospectively collected: genetic variants in CNGA1 and CNGB1, best-corrected visual acuity (BCVA), ellipsoid zone (EZ) width, fundus photographs, and short-wavelength fundus autofluorescence (SW-AF) images. Comparisons and correlation analyses were performed by first dividing the cohort in two groups according to the gene responsible for the disease (CNGA1 and CNGB1 groups). In parallel, the whole cohort of RP patients was divided into two other groups, according to the expected impact of the variants at protein level (low and high group). Results: In total, 29 patients were recruited, 11 with CNGA1- and 18 with CNGB1-related RP. In both CNGA1 and CNGB1, 5 novel variants in CNGA1 and 5 in CNGB1 were found. BCVA was comparable between CNGA1 and CNGB1 groups, as well as between low and high groups. CNGA1 group had a larger mean EZ width compared to CNGB1 group, albeit not statistically significant, while EZ width did not differ between low and high groups A statistically significant correlation between EZ width and BCVA as well as between EZ width and age were observed in the whole cohort of RP patients. Fundus photographs of all patients in the cohort showed classic RP pattern, and in SW-AF images an hyperautofluorescent ring was observed in 14/21 patients. Conclusion: Rod CNG channel-associated RP was demonstrated to be a slowly progressive disease in both CNGA1- and CNGB1-related forms, making it an ideal candidate for gene augmentation therapies.
Description and Characteristics of Ocular Tumor Lysis Syndrome
Authors: de Carlo Forest Talisa E. , Oliver Scott C.N.
Published: May 2024

Introduction: The aim of the study was to describe and evaluate characteristics of ocular tumor lysis syndrome (OTLS) in eyes with uveal melanoma. Methods: Retrospective chart review of all patients with OTLS at the University of Colorado from 2009 to 2021. Data collected included patient demographics, tumor characteristics, radiation dosimetry, gene expression profiling (GEP), OTLS characteristics, management, and outcomes. Results: Seven eyes of seven patients with uveal melanoma treated with I-125 brachytherapy developed OTLS. Average age was 59 years (range 32–83). Mean apical height was 8.6 mm (range 6–11); mean diameter was 12.7 mm (range 8.5–15.3). All tumors were treated with plaques ≥16 mm in diameter. On presentation, 5/7 tumors had subretinal fluid, and 6/7 had collar-button configuration. OTLS presented as extensive pigment dispersion in the vitreous in all eyes, subretinal pigment and/or retinal detachment in 4/7 eyes, vitreous hemorrhage in 2/7 eyes, and anterior chamber pigment in 3/7 eyes. Four tumors were GEP class 1, two were class 2, and one was unclassified. Biopsy route was trans-scleral in 4/7 eyes and trans-vitreal in 3/7 eyes. OTLS occurred 2–4 weeks after an intraocular procedure in 5/7 eyes. All underwent pars plana vitrectomy. Cytology of the vitreous, obtained in five cases, showed pigment laden macrophages and hemorrhage, but only 1/5 eyes had viable malignant cells. Four eyes were stable at the last follow-up, two were enucleated, and one had no light perception from pigmentary glaucoma. Poor vision (<20/200) occurred in 6/7 cases. Three patients died from metastasis (tumors were GEP class 2, GEP class without subclassification, and no GEP classification performed). Conclusions: OTLS is a rare but devastating complication of uveal melanoma. Common characteristics included large plaque diameter, presence of subretinal fluid, and collar-button shape. The extensively dispersed pigment is typically not malignant. Though poor vision is common, enucleation may be avoided in most eyes through vitreoretinal surgical repair.
Acupuncture Point Selection Patterns for Chemotherapy-Induced Nausea and Vomiting: A Data Mining Analysis
Authors: Ke Zi , Chen Hongruyu , Zhao Yong , Ke Jixian , Xie Youqiong , Zeng Runxin , Hua Yini , Xiong Zhihao , Wang Xuanxuan
Published: May 2024

Introduction: Chemotherapy-induced nausea and vomiting (CINV) significantly impacts the quality of life of cancer patients undergoing treatment, often leading to treatment interruptions and compromised adherence to therapy. Our objective was to identify patterns for selecting the optimal acupoints and explore the treatment principles behind forming effective acupoint combinations for CINV. Methods: Clinical trials were retrieved from eight databases. Descriptive statistics analysis was performed, followed by association rule mining, network analysis, hierarchical cluster analysis, and correlation analysis, all implemented with R software. Results: In summary, this study investigated the potential acupoints and combinations for CINV treatment in 104 published controlled clinical trials and randomized controlled trials. 104 prescriptions involving 48 acupoints were extracted. ST36, PC6, CV12, SP4, LI4, and ST25 appeared to be the most frequently used acupoints for CINV. Stomach Meridian, Conception Vessel (Renmai), and Pericardium Meridian were the most common selected meridians. The lower limbs, chest, and abdomen appeared as the predominant sites for acupoint selection. Co-occurrence network analysis indicated that ST36, PC6, and CV12 were central key node acupoints. The clustering analysis displayed the treatment principle of “harmonizing the stomach, stopping vomiting, and descending counterflow.” Association rule mining revealed that the combination of CV4, CV12, ST36, CV6, and PC6 emerged as the optimal acupoint combination for effectively treating CINV. Conclusion: Overall, our research provides evidence-based optimal acupuncture prescription for acupuncturists to treat CINV and presents a complementary therapy for chemotherapy physicians as well as patients to address CINV symptoms.
Effect of 60-Min Single Bout of Resistance Exercise, Reformer Pilates, on Vascular Function Parameters in Older Adults: A Randomized Crossover Study
Authors: Rangabprai Yupawan , Mitranun Witid , Mitarnun Witoon
Published: May 2024

Introduction: Aging leads to vascular endothelial dysfunction and muscle impairment. While resistance exercise improves muscular function, its acute effects on vascular function vary in the literature, with some studies reporting detrimental effects. These findings indicate the need for exercises that optimize muscle function without compromising vascular function. Reformer Pilates (RP) is a low-impact exercise involving an adjustable sliding platform. However, the acute effects of RP on vascular function among older adults remain unknown. Therefore, this study aimed to investigate the acute effects of RP on vascular function in older adults. Methods: Overall, 17 participants (age: 65 ± 2.76 years, body mass index: 23.42 ± 3.68 kg/m2) were examined and assigned to control and RP conditions under a randomized crossover design. The RP condition involved a 3.5–5 omnibus perceived exertion scale with 19 exercise postures for 60 min. Brachial artery flow-mediated dilation (FMD), brachial-ankle pulse wave velocity (baPWV), and blood pressure were measured at baseline and 0, 10, 30, and 60 min after exercise. Results: RP significantly improved FMD at all time points compared with that at baseline (p < 0.05). baPWV increased at 0 min post-RP but returned to baseline levels at other time points. Additionally, RP showed improved FMD at 0, 10, and 30 min compared with that in the control condition (p < 0.05). However, no significant differences were observed in blood pressure or mean arterial pressure in either condition. Conclusion: RP enhanced FMD and regulated blood pressure for approximately 60 min post-exercise, suggesting its suitability for older adults to enhance vascular function and control blood pressure during exercise. Nonetheless, longitudinal resistance training intervention studies are needed to validate these findings.
Beyond the Neurologist: Charles Foix as a Poet and a Playwright
Authors: Tessaro Camila Lorenzini , Doubek João Gabriel Cavazzani , Pedro Matheus Kahakura Franco
Published: May 2024

Background: Charles Foix (1882–1927) may be mostly remembered today due to his contributions to vascular neurology and the syndromes that bear his name, such as the Foix-Alajouanine syndrome. However, he also developed a literary career and composed poetry and a vast collection of plays, often dealing with biblical themes or figures from Greek mythology. Summary: His poetry was often inspired by his own experiences during the First World War, in which he was assigned to serve as a medical officer in Greece, becoming enamored with his surroundings and the classical lore. Key Messages: The authors explore Foix’s poetry and drama and their relationship to his overall work as a neurologist, including his wartime experiences.
Historical Perspective of High-Dose Therapy Followed by Autologous Stem Cell Transplantation in Multiple Myeloma
Authors: Cohen Inbar , Vaxman Iuliana , Gertz Morie A.
Published: May 2024

Background: High-dose therapy (HDT) followed by autologous stem cell transplantation (ASCT) has become part of standard of care (SOC) in newly diagnosed multiple myeloma. In this review, we provide a historical perspective on ASCT since its introduction in the 1990s. Summary: Overall survival (OS) benefit for HDT followed by ASCT was demonstrated in studies comparing HDT with ASCT to standard-dose therapy (SDT) before the era of novel agents. Conditioning is done with melphalan 200 mg/m2. Lower doses (MEL140, MEL150) for older patients with comorbidities are safe and have comparable results. The addition of busulfan to melphalan improves progression-free survival (PFS) but not OS. HDT with ASCT after induction with novel agents prolongs PFS but not OS compared to SDT alone. The benefit is more evident in patients with high-risk cytogenetics. Mobilization can be achieved with granulocyte colony-stimulating factor alone, but is improved with the addition of chemotherapy. Plerixafor reduces mobilization failure and enables sufficient stem cell collection after induction with novel agents. ASCT is safe with a low rate of mortality (1%), and selected patients can be managed as outpatients. Key Messages: HDT followed by ASCT remains part of SOC due to its PFS benefit and relatively low toxicity.
Práticas artísticas comunitárias como promotoras de conhecimento-emancipação
Authors: Silva Daniela Mota , Silva José Eduardo
Published: May 2024

Este artículo tiene como objetivo explorar las Prácticas Artísticas Comunitarias (PAC) como posibilidad contrahegemónica de socialización y construcción de mundo desde las artes escénicas. Trataremos de entender cómo las PAC pueden ser una alternativa a las formas convencionales de construir conocimiento y hacer arte, ya que reúnen las condiciones necesarias para la formación del conocimientoemancipación. Para ello, se utilizarán como fundamento teórico los conceptos de teoría/pedagogía decolonial y Epistemologías del Sur.
Interculturalidade em debate: tensões e articulações de um campo em disputa
Authors: Melo Rafael de Lemos
Published: May 2024

¿Cuáles son las intersecciones y fricciones que ocurren cuando analizamos el fenómeno de la interculturalidad desde la perspectiva de las teorías poscoloniales y cómo estos análisis pueden mejorar nuestras reflexiones y procesos creativos de quienes se mueven por los espacios de diferencia cultural? A partir de estas preguntas, este artículo presenta un mapeo de las prácticas transculturales realizado por Jacqueline Lo y Helen Gilbert, las críticas a la interculturalidad de Rustom Bharucha y las propuestas para una nueva interculturalidad, articuladas por Royona Mitra a partir del análisis de obra del coreógrafo Akram Khan.
Dramaturgias negras do sul: assentamentos culturais e políticos da cena amefricana do Pampa
Authors: Piegaz Acevesmoreno Flores
Published: May 2024

Este artículo reflexiona sobre las dramaturgias negras producidas en la pampa sudamericana, en la segunda década del siglo XXI, a partir de las obras Cavalo de Santo (Brasil), La Diosa y la noche: el musical de Rosa Luna (Uruguay), y No es país para negras II (Argentina) desde perspectivas afrocéntricas. El enfoque considera la existencia de una Pampa amefricana desde la perspectiva de la antropóloga Lélia González y busca analizar la dramaturgia que sostiene la escena teatral a partir de las categorías de ascendencia, reexistencia, agencia y lucha antirracista para comprender las características, enfoques y aportes al proceso de reterritorialización de la negritud en el Sur.
Laborarte: pioneirismo decolonial no teatro maranhense
Authors: Conceição Raylson Silva da , Fonseca Michelle Nascimento Cabral
Published: May 2024

This research aims to investigate the impact of Laborarte on the Brazilian theater, with a focus on its decolonial approach. Its theoretical framework encompasses decolonial theories, political theater, and the Maranhense culture. This study aims to analyze Laborarte’s contribution to deconstructing stereotypes, promoting local culture, and fostering social justice in the Maranhense theater. Its methodology includes an analysis of theatrical texts, interviews, and historical context analysis. Results highlight Laborarte’s pioneering role in theatrical decolonization, influencing subsequent productions to embrace an inclusive and just perspective of the Maranhense reality.
A construção de políticas públicas para as Bibliotecas Escolares da Rede Municipal de Ensino de Vitória/ES: perspectivas e desafios
Authors: Corrêa Mariluce de Souza , Uliana Elane Couto , Falcão Roberta Trindade , Gonçalves Andréa Carla , França Fabiana Fernandes , Rosa Daniele Achilles Dutra da
Published: May 2024

Apresenta um relato de experiência sobre a construção de políticas públicas para as bibliotecas escolares da rede de ensino do Município de Vitória/ES, demonstrando um panorama atual dela. Traduz a metodologia utilizada nesse processo e aponta conteúdos considerados de abordagem essencial e aplicadas à redação de documentos que atendessem às necessidades dos bibliotecários e da comunidade escolar. Destacam-se a Política do Livro, da Leitura e das Bibliotecas e as Diretrizes para Bibliotecas Escolares, que se convertem na primeira ação efetiva de institucionalização da Rede. Tais documentos foram desenvolvidos visando comunicar aos demais membros da comunidade escolar as potencialidades e desafios desse espaço frente às demandas sociais, educacionais e culturais. Conclui-se que as políticas públicas fortalecem as bibliotecas escolares e consolidam o trabalho do bibliotecário.
Esse cacilheiro sou eu: despertença em Tornado de Teresa Noronha
Authors: Sousa Sandra
Published: May 2024

This article focuses on Teresa Noronha’s recent novel, Tornado (2021), which received the Maria Velho da Costa Award from the Portuguese Society of Authors. From Edward Said’s memoir Out of Place (1999), in which he explores the concept of exile as a way of inhabiting space with the constant awareness that one is not at home, I intend to examine how Noronha’s novel surrenders and, at the same time, expands this condition so dear to Said. At the same time, I intend to analyze the complex network of so-called racial relations in Mozambique, and how they contributed to the formation of a self  marked by difference and, consequently, to its inner shattering. The feeling of estrangement leads the narrator to an inner exile and, later, an outer exile in search of herself.
Profile of Self-Regulation and Social Activity in the Portrait of Russian Youth
Authors: Bubnovskaia Оlesia V. , Kalita Vitaliy V. , Lysova Alexandra V. , Sokolovskii Maksim L.
Published: May 2024

Background. The relevance of studying the social activity of young people in the context of self-regulation is determined by the vulnerability of young people in difficult conditions of a transforming society subject to uncertainty. In social activity, young people socialize, manifest themselves, and therefore it is necessary to understand its factors, motives for inclusion in one or another of its forms, obstacles to its implementation, as well as risks and threats to the safety and well-being. Objectives. The aim is to establish the role of self-regulation in the involvement of young people in social activity, considering regional and gender specifics. Study Participants. This study involved 1492 respondents (Mage = 19.2; 1013 women), students of various majors from Russian regions. Methods. The research had a survey design, the questionnaires and scales were used in this work for collecting data: V.I. Morosanova's “Style of self-regulation of behavior”, Eysenck's three-factor model, FIRO-B, British scale of well-being, Scale of Russian parties and socio-political organizations attractiveness, Assessment of social contacts intensity and participation in events, and informal associations, a socio-demographic survey. Methods of descriptive statistics, cluster (k-means method) and comparative (t-Student and H-Kraskel-Wallis criterion) analyses were used for data processing. Results. It is established that the leading regulatory processes and properties in the profile of self-regulation of young people are persistence, programming of actions, and flexibility. Self-regulation has a greater impact on such forms of social activity of young people as leisure activities, participation in clubs, spontaneous events as the organizer of these forms with a predominant value for girls rather than for boys. Conclusions. The study showed the typical features of the self-regulation profile of young people. This profile is mostly conditioned by the age specifics of this social group. The limited influence of the processes and properties of self-regulation on the forms of social activity, especially in relation to young men, suggests the need to consider other factors of social activity in a complex.
The Evolution of the Hebronite Regionalism 1929–48
Authors: Chorev-Halewa Harel
Published: May 2024

The article discusses the integration of the Mount Hebron area into a distinct social and political region during the time of British Mandate in Palestine and the emergence of a regional “Hebronite” identity encompassing both the city of Hebron and the villages of the area. The study demonstrates that, while in many areas of the country such regional integration, or regionalization, developed through the gradual growth of economic, administrative, and political networks in the nineteenth century, the regionalization of Mount Hebron took place much later. It was not an outcome of the same dynamics as in other regions, but mainly a reaction born of chronic insecurity, as well as the social and even environmental hardships experienced in the region. In the 1940s, the determination to overcome these challenges was translated into the construction of a stable regional system that had significant intra-Palestinian and even geopolitical consequences. The study also shows that, while the Hebronite identity was a sub-national one, it had strong symbiotic, sometimes ambivalent, relations with the Palestinian and Arab national identities. Moreover, it was in no way a primordial but clearly a modern phenomenon.
Electrophysiological Activity Associated with a Cross-Modal Anapaest Rhythm: Evidence for the Vestibular Syncopation Hypothesis
Authors: Todd Neil P.M. , Keller Peter E. , Govender Sendhil , Colebatch James G.
Published: May 2024

We report an experiment that tested the vestibular syncopation rhythm hypothesis, which holds that the rhythmic effect of syncopation is a form of vestibular reflexive/automated response to a postural perturbation, for example during locomotion. Electrophysiological signals were recorded from the cerebral cortex and cerebellum during processing of rhythmic sequences in a sample of experienced participants. Recordings were made using four different stimulus modalities, auditory, axial, vestibular and visual, under different rhythmic timing conditions, irregular, regular and syncopated/uncertain. Brain current activity was measured using a model with10-dipole source regions of interest in each of the participants, each modality, each timing condition, and for each beat within the bar of the rhythm. The cross-modal spectral power in the frontal electroencephalogram (EEG) and the cerebellar electrocerebellogram (ECeG) was also analysed. The results show that the brain activity increases from the irregular to the regular and then from the regular to the uncertain timing conditions. However, the vestibular modality induces the greatest total brain activity across the regions of interest and exhibits the highest sensitivity to the interaction of beat structure with the timing conditions in both source currents and spectral power. These data provide further evidence to support the primal role of the vestibular system in human processing of rhythm.
Two new wood-inhabiting fungal species (Polyporales, Basidiomycota) from Yunnan Province, China
Authors: WANG LU , SU JIANGQING , MUHAMMAD AKMAL , ZHAO CHANGLIN
Published: May 2024

Wood-inhabiting fungi are a cosmopolitan fungal group worldwide. Two new wood-inhabiting fungal species, Rhodoantrodia purpurascens and Steccherinum wumengshanense are proposed based on a combination of the morphological features and molecular evidence. Rhodoantrodia purpurascens is characterized by the corky basidiomata with a pale lilac to lavender pore surface, a dimitic hyphal system with clamped generative hyphae, and broadly ellipsoid basidiospores. Steccherinum wumengshanense is characterized by the corticoid basidiomata having a white to cream hymenial surface, a monomitic hyphal system with clamp generative hyphae, and ellipsoid basidiospores. Full descriptions, photo plates and phylogenetic analysis results of the new species are provided.
A new genus and one new species of the family Uristidae Hurley, 1963 (Amphipoda, Lysianassoidea) described from hydrothermal vent of the Okinawa Trough, NW pacific
Authors: WANG YAN-RONG , SHA ZHONG-LI
Published: May 2024

A new genus of the family Uristidae Hurley, 1963 is proposed, Liuiuristis gen. nov., with new species L. thermalis sp. nov. as the type species based on specimens collected by the expedition to hydrothermal vents on the Okinawa Trough. The new genus is characterized by the shape of accessory flagellum liking cap, the outer plate of the maxilla 1 having 11 setal-teeth, the gnathopod 1 parachelate in female and subchelate in male, the rami of the uropod 3 without plumose setae and the telson not cleft. K2P divergences of the mitochondrial COI gene in taxa attributed to Liuiuristis gen. nov. is presented.
4. The Many Lives of Jesus
Authors: Clossey Luke
Published: May 2024

This chapter examines some of the sources of the Jesus information available in 1400. We begin with the Qur'an, to explain both its special nature and its importance for the Jesus cult. Turning beyond canon, we then consider four unusual kinds of Jesus-related written documents: charters that spoke in legal language, gospel harmonies that blended the four canonical Gospels into a single narrative, a passage from Mirkhvand's paracanonical expansion of the Qur'an, and the Toledot Jesu, a hostile retelling of the Jesus life from a Jewish perspective. These elaborations and elisions of the canonical material reveal the priorities and values of the societies that first created and then repeated them. They also employ a range of approaches, from the poetic and deep-ken recognition that those who choose not to see were literally blind, to the fifteenth-century discovery or manufacture of a first-century Jewish apologetic speaking directly to an imagined audience that thought with the plain ken.
6. Internal Frontiers between Jews, Christians, Muslims
Authors: Clossey Luke
Published: May 2024

This chapter looks at two “internal” frontiers of the Jesus cult. The first is the border between the Muslim and Christian subcults in the growing Ottoman Empire. Christians converted to Islam, even as both traditions fused together at a level beneath formal identity, as in Bektashism and Hurufism. Muslims used Christian baptism as a deodorant, or recognized the Persian mystic Fazlallah Astarabadi as Jesus, or claimed Jesus as a prophet equal to Mohammad. The second frontier divided Jews and Christians in Iberia—a border within a Christian society. In the Disputation at Tortosa, Christians seeking to convert Jews stressed the Bible's identification of Jesus as the messiah as well as the rational necessity of his incarnation. The Jewish leaders' counterarguments were often oriented towards the plain ken: Christians used an err-riddled translation of the Hebrew Bible, ignored historical context, and too quickly abandoned the literal meaning for the figurative. Taking the plain ken to history, the defenders of Judaism argued that material success, the kind the Jews lacked, was no guarantee of truth. Both frontiers witnessed social unrest and personal tragedy.
9. The Eucharist in its Liturgical Context
Authors: Clossey Luke
Published: May 2024

This chapter explains the logistics of the liturgical calendar and the eucharistic ritual. On the production side, the number of masses performed was not chosen for its resonance, but was maximized based on worldly constraints—the availability of space (the number of altars), money, and time. Similarly, on the consumption side, enthusiasts running between churches sought to behold the highest possible number of masses, a number without any deep-ken meaning. In the deep ken, the glory of the mass was optimized by carefully orchestrating time, place, and other circumstances so they would consonate with each other. In contrast, the interest in maximizing the number of heard masses depended more on the plain ken. Especially in Bohemia and England, but even as far away as Tunisia, critics expressed pointed doubts that the eucharist ritual could turn wine and bread into Jesus's body and blood. Often these objections assumed a plain ken regarding space, which created obstacles to the transformation of matter, to the perception of the invisible, and to the possibility that Jesus could exist simultaneously across the breadth of Christendom. Other critics fought over interpretations of the Jesus's words used to institute the mass. The intensity of these debates fuelled rumours of desecrations. A number of miracles demonstrated that the consecrated host was powerful, indestructible, and unable to be misplaced. Local and transregional cults developed around hosts that bled to empirically drown out all these intellectual controversies.
18. Elevated Speech and Song
Authors: Clossey Luke
Published: May 2024

Focussing on Christian performance of their liturgy, and Muslim recitation of their Qur'an, this chapter looks at more systematic and controlled ways of vocalizing the word “Jesus” and Jesus-related texts, in terms of factors like pronunciation, volume, breath control, and coordination with other peoples' utterances. Systematizing Jesus vocalization with regular rules created subtle connections accessible only through the deep ken. Some Muslims scholars, especially, inclined towards the plain ken did take into account human limitations and historical, cultural particularities, as with Al-Suyuti's interest in the Bedouins. Examples treated in the chapter include the sequence Victimae Paschali Laudes, which outside of its liturgical context was sung while performing a ballgame-dance at Easter in France. Polyphony was explicitly linked to Jesus, who was the only person able to speak and sing polyphonically simultaneously. Deep-ken meaning was brought into polyphonic liturgical music, especially through the use of a cantus firmus and through mathematics. Josquin's masses (especially those built upon the secular tune “L'homme armé”), among others, numerically encoded Jesus references. Both polyphony and its use of secular melodies provoked condemnation.
19. Resembling Jesus
Authors: Clossey Luke
Published: May 2024

This chapter looks at less literal examples of imitation of, and proximity to, Jesus. Some cultists moved closer to Jesus by imitating him, and others found deep-ken significance in parallels between Jesus and their notable contemporaries. Some, on a continuum from actors to kings, behaved--or were seen to behave--in ways that created a deep-ken consonance between themselves and Jesus. Some of the imitators imitated his poverty through nudity, and his passion through flagellation, which practices became intimate, and sexual, in the eyes of some authorities. Some cultists interacted with Jesus in very concrete ways, in plain-ken time and space, even to the point of marriage.
21. Ethics, Pacifism, Vegetarianism
Authors: Clossey Luke
Published: May 2024

The dominant approach to ethics in the fifteenth-century Jesus cult was oriented towards the deep ken. The chapter begins with an overview of what such ethics looked like, and then zooms in on two particular themes, investigating the deep-ken approach to issues of pacifism and vegetarianism. Neither resembles our modern attitudes towards ethics, and deep-ken vegetarianism was only tenuously linked with ethics at all. This century saw related shifts from the deep to the plain ken: from a history that transcended time to a history fractured in the first century and bent once or twice after that, from an ethics based on symbolic consonance to a constructed, articulated ethics, and from a peace based on universal harmony to one based on the actions and emotions of humans. With a focus on Jesus’s Sermon on the Mount and its consequences, this chapter outlines this shift by considering both people committed to non-harm (the Waldensian Poor of Lyon, Nicholas of Hereford, Nicholas of Dresden, Petr Chelčický, Francis of Paola) as well as radical conservatives (Luke of Prague, Erasmus) who took plain-ken paths to more moderate positions.
1. Introduction
Authors: Khan Geoffrey
Published: May 2024

The introduction presents a description of the geographical region of Nubia followed by an overview of its history from late antiquity until the Mamluk period. Christianity was introduced into Nubia in the sixth century AD under the auspices of the church organisation of Byzantine Egypt, and subsequently the churches of the region came under the jurisdiction of the Coptic patriarchate of Alexandria. At that period Nubia consisted of three kingdoms: Nobadia, Makuria and Alodia. These kingdoms were subsequently united in a single kingdom with its capital at Dongola. In the early Islamic period the Muslims invaded Nubia, but failed to conquer the region. A peace treaty was drawn up between the Muslims and the Nubians known as the baqṭ. Nubia remained an independent Christian kingdom until the thirteenth century AD , when finally the Muslim Mamluks took control of the Nubian capital of Dongola.