bluuebunny/crossref_metadata_2025 huggingface dataset:
FORMULATION, OPTIMIZATION AND CHARACTERIZATION OF IBUPROFEN LOADED MICROEMULSION SYSTEM USING D-OPTIMAL MIXTURE DESIGN
Authors: ALAOUI YASSIR EL , FAHRY AICHA , RAHALI YOUNES , CHERKAOUI NAWAL , BENSOUDA YAHYA , LAATIRIS ABDELKADER
Published: July 2019

Objective: The purpose of this study was to develop, optimize and characterize a stable microemulsion, with an improvement of the solubility of a poorly aqueous soluble drug, ibuprofen.

Methods: Various oils (oleic acid, cottonseed oil, olive oil, argan oil, and labrafac® WL 1349), surfactants (tween® 80, tween® 40, tween® 20) and co-surfactants including polyethylene glycol 400, ethanol, 1-butanol, and propylene glycol were selected after solubility studies. Then, pseudo-ternary phase diagrams with surfactant/co-surfactant ratio of 1:2, 1:1, 2:1 and 3:1 were constructed and a D-optimal mixture design method was used to optimize the ibuprofen loaded microemulsion. The optimized microemulsion was evaluated for several characteristics including globule size, zeta potential, pH, conductivity, refractive index and stability studies.

Results: Optimized microemulsion obtained was composed of oleic acid (6.88% w/w), tween® 80/1-butanol (3:1, 63.11% w/w) and water (30.00% w/w). The results obtained showed an average globule size of 117.5 nm, a zeta potential of-6.47 mV and a transmittance of 96.95±0.77%. The optimized formulation showed an improvement in the solubility of ibuprofen with unchanged characteristics for one month.

Conclusion: The use of pseudo-ternary phase diagrams and mathematical modeling allows to obtain an optimal microemulsion with perfect stability for 1 mo and a better solubilization capacity of ibuprofen.
METHOD VALIDATION OF RIFAMPICIN ANALYSIS IN HUMAN PLASMA AND ITS APPLICATION IN BIOEQUIVALENCE STUDY
Authors: LUKITANINGSIH ENDANG , JANNAH FATHUL , PEBRIANA RATNA BUDHI , PUSPITA RATNA DEWI , . TAUFIQUROHMAN , IKAWATI ZULLIES
Published: July 2019

Objective: This research aims to validate the method for rifampicin analysis in plasma by using High-Performance Liquid Chromatography (HPLC) that can be used to study the bioequivalence of a generic tablet of rifampicin 450 mg “X” marketed in Indonesia.

Methods: Bioequivalence test was analysed using HPLC equipped with UV-Vis detector at 377 nm. The mobile phase used was acetonitrile-phosphate buffer pH 6.8 (45:55) delivered at a flow rate of 1.5 ml/min. Bioequivalence test was conducted on a limited number of subjects (n=8). The subjects were divided into two groups randomly. The pharmacokinetic profiles of the test tablet and reference tablet were statistically calculated using SPSS program to see the test tablet and reference tablet were bioequivalence or not.

Results: The developed HPLC method for rifampicin analysis in plasma was sufficiently valid based on the International Conference on Harmonization (ICH) and European Medicines Agency (EMA) guideline, with precision and accuracy values were % Relative Standard Deviation (% RSD = 1.40–13.04) and % Recovery (86.24–102.13), respectively. Meanwhile, the method was linear over studied concentration (0.05 to 10.26 µg/ml) with a coefficient of determination (R2) = 0.9984. The method also had good stability and sensitivity. The result of statistical calculation showed that the generic rifampicin tablet X was bioequivalence toward the reference tablet Rimactan 450 mg.

Conclusion: The test rifampicin tablet that was, the generic tablet “X” was bioequivalence toward the reference rifampicin tablet “Rimactan”.
PREPARATION AND CHARACTERIZATION OF CHITOSAN/REGENERATED SILK FIBROIN (CS/RSF) FILMS AS A BIOMATERIAL FOR CONTACT LENSES-BASED OPHTHALMIC DRUG DELIVERY SYSTEM
Authors: JEENCHAM RACHASIT , SUTHEERAWATTANANONDA MANOTE , Tiyaboonchai Waree
Published: July 2019

Objective: The aim of this study was to develop chitosan/regenerated silk fibroin (CS/RSF) films as a biomaterial for contact lenses-based ophthalmic drug delivery system.

Methods: CS/RSF films were prepared with polyethylene glycol 400 as a plasticizer by using a film casting technique. Their physicochemical properties were investigated by measuring various properties such as thickness, morphology, chemical interaction, light transparency, mechanical properties, water content, oxygen permeability, thermal properties and enzyme degradation. In addition, cytotoxicity was also studied.

Results: At optimal preparation conditions, CS/RSF films showed smooth surfaces with highly visible light transparency of >90%, which meet the visual requirement. CS/RSF films showed high water content, 59-65% by weight, and their Young’s modulus and elongation at break was in the range of 3.8-6 N/mm2 and 113-135%, respectively. The CS/RSF films also could be sterilized by autoclave method as they possessed high thermal decomposition temperature of >260 °C which can be confirmed by both differential scanning calorimetry and thermogravimetric analysis. In addition, CS/RSF films showed no degradation in stimulated tear fluid containing lysozyme for 7 d and showed no cytotoxicity by MTT assay.

Conclusion: CS/RSF films showed excellent physicochemical properties and non-cytotoxicity indicating their promising potential use as a biomaterial for contact lenses-based ophthalmic drug delivery system.
DEVELOPMENT AND CHARACTERIZATION OF CREAM CONTAINING NANOSTRUCTURED LIPID CARRIERS FOR HAIR SPLIT-END REPAIRING
Authors: Prasertpol Tashatai , Tiyaboonchai Waree
Published: July 2019

Objective: This study aimed to develop the nanostructured lipid carriers (NLCs) for repairing the hair split-end and to compare the influence of NLCs charges on hair binding effects.

Methods: NLCs was prepared by a high-pressure homogenization technique. The difference solid lipids were selected to obtain the negatively charged NLCs (N-NLCs) and positively charged NLCs (P-NLCs). The physical characterizations of both NLCs were examined. The NLCs cream was prepared by mixing NLCs into a cream base. Then, the hair split-end binding effects of the NLCs cream were assessed. The physical stability of both NLCs were investigated by kept at room temperature for 6 mo.

Results: The N-NLCs and P-NLCs were successfully prepared with a zeta potential of -44.4 mV and 32.3 mV, respectively. They were a spherical shape with a similar mean size of ~150-160 nm. The hair split-end evaluation showed that both NLCs illustrated similar hair split-end binding time of more than 3 d, suggesting no extra benefit from the positively charged of P-NLCs. On the contrary, the cream base and commercial product showed a short binding time of <8 h. Furthermore, after 6-mo storage, N-NLCs demonstrated good physical stability without particle aggregation, while P-NLCs exhibited a phase separation.

Conclusion: The developed NLCs is a novel alternative for the leave-on product, which would be highly benefits for hair split-end repairing.
DEVELOPMENT OF SEMISOLID PREPARATIONS CONTAINING EXTRACT OF THAI POLYHERBAL RECIPE FOR ANTI-INFLAMMATORY EFFECT
Authors: Gunsuang Sirawan , Jaipakdee Napaphak , Mahakunakorn Pramote , Limpongsa Ekapol
Published: July 2019

Objective: The objective was to develop the semisolid preparations containing extract of Thai polyherbal recipe with anti-inflammatory effect.
Methods: Polyherbal ethanolic extract was prepared by maceration and determined for phytochemicals and antioxidant activity. Effects of extract on the production of pro-inflammatory mediator-nitric oxide (NO)-were examined in RAW 264.7 cells. Semisolid preparations, balm, and gel, were prepared and evaluated. In vitro release profiles and mechanisms of phenolic compounds, phytochemical markers, from the preparations were investigated.
Results: Polyherbal ethanolic extract was dark yellow-green, viscous liquid with the yields of 8.2%. Total phenolic and total flavonoid contents were 121.21±1.60 mg GAE/g and 26.55±1.38 mg QE/g, respectively. Antioxidant assay showed that polyherbal extract can scavenge the radical to a certain extent, with DPPH IC50 of 160.75±3.43 µg/ml and FRAP values of 91.94±4.17 mg FeSO4/g. In vitro anti-inflammatory test revealed that the extract inhibited NO production in a dose-dependent manner, with IC50 of 145.65±3.26 µg/ml. The yellowish-green color, homogenous and suitable for skin application polyherbal balm and gel was obtained. The higher release of phenolics from the gel was observed, with the cumulative release at 8 h of 119.0±4.3 mg GAE, whereas that from the balm was only 39.7±2.0 mg GAE. The phenolic release profile was found to be best fitted with the Higuchi model.
Conclusion: The semisolid preparations containing Thai polyherbal recipe extract with anti-inflammatory effect were successfully prepared. The proper semisolid base and compositions are crucial for effective skin delivery as they influence the release rates of phytochemical markers.
PENGARUH PH DAN WAKTU PENYIMPANAN TERHADAP PERTUMBUHAN Lasiodiplodia theobromae PENYEBAB KANKER BATANG TANAMAN KARET
Authors: Febbiyanti Tri Rapani , Widodo Widodo , Wiyono Suryo , Yahya Sudirman
Published: July 2019

Lasiodiplodia theobromae merupakan cendawan penyebab kanker batang pada tanaman karet (Hevea brasiliensis Muel Arg.), penyakit ini merupakan penyakit baru dan belum pernah dilaporkan sebelumnya di Indonesia.  Banyak cara yang dapat dilakukan untuk mengendalikan penyakit kanker batang. Strategi pengendalian yang terbaik adalah dengan pengelolaan penyakit yang membutuhkan pengetahuan mengenai ekobiologi patogen, inang, dan interaksinya dengan lingkungan biotik dan abiotik. Pengendalian patogen harus didasarkan pada pengetahuan tentang bioekologinya. Diharapkan dengan pengetahuan bioekologi bisa dijadikan dasar untuk bisa menghambat perkembangan atau menurunkan populasi inokulum di lapangan. Penelitian ini bertujuan untuk menentukan pengaruh pH secara in vitro terhadap pertumbuhan patogen kanker batang dan laju penurunan viabilitas tubuh buah akibat penyimpanan.  Kisaran pengaruh pH media meliputi 3, 4, 5, 6 dan 7. Penyimpanan tubuh buah dilakukan dalam wadah tanpa diberi tanah, diberi tanah steril dan tanah tidak steril. Penentuan viabilitas dilakukan pada 30, 60, 90 dan 120 hari masa penyimpanan. Semakin rendah pH menyebabkan pertumbuhan miselia terhambat.
INOVASI MEDIA PEMBELAJARAN BAHASA ARAB BERBASIS E-LEARNING
Authors: Silahuddin Silahuddin , Azhari Azhari
Published: July 2019

The Arabic teaching-learning proccess at the Madrasah Aliyah in Aceh Besar has not been running optimally. Generally, the learning process is still conventional based. Therefore, a solute efforts is needed for a teacher to design and create learning medias based ICT. Namely: computer-based media, websites, online library, e Learning and android that can facilitate the spread of knowledge. This research are to investigate how the utilization of ICT can be used optimally in learning and how the ability of teachers in using ICT facilities as a learning media innovation. The research used is a research development with mixed method methodology, and the sample of the research is Madrasah Aliyah teachers in Aceh Besar District. The results showed: generally, the teachers have already known and understood the use of media in learning. Nevertheless, Teachers rarely most of them do not use e learning. The teachers have not done the innovation of learning media of ICT based. The researcher recommends. The Medias e learning can be used optimally in learning Arabic at Madrasah Aliyah Aceh Besar District.
Agronegocios, pueblos indígenas y procesos migratorios rururbanos en la provincia de Salta, Argentina
Authors: Flores Klarik Mónica
Published: July 2019

Este trabajo aborda los efectos de los agronegocios sobre la vida cotidiana de las comunidades wichí de la provincia de Salta, Argentina, enfocándose en los procesos de migración rural urbana a causa de los desmontes. Se parte del supuesto de que asistimos a un proceso de reconfiguración territorial y urbanización de la vida, producto del modelo neoextractivista, que genera una doble desvinculación de la población rural con respecto a la tierra y al trabajo, einhabilita la reproducción cultural y la subsistencia de los pueblos indígenas. Estos cambios se analizan a partir de un estudio estadístico y desde un enfoque etnográfico se desvela la visión de las comunidades, así como las distintas formas de resistencias que llevan a cabo para defender su medio de vida.
Las Competencias Gerenciales en la Gestión de Instituciones de Educación Superior
Authors: Aristimuño V. Minerva , Guaita Wilfredo
Published: July 2019

Esta investigación tiene como objetivo estudiar los componentes de las competencias gerenciales requeridas por directivos o gestores de las Instituciones de Educación Superior (IES). En este sentido, se determinan, de acuerdo a la percepción de los docentes que han desempeñado cargos de dirección en las IES estudiadas, cuálesdeberían ser las competencias de los cuadros directivos o gerenciales y como se interrelacionan estas competencias entre sí. Dado que el objeto de estudio son los docentes que tienen o han tenido cargos de autoridad en las IES estudiadas en susrespectivas organizaciones para-universitarias y/o gremiales, se determinó que la población total está constituida por 69 docentes, por lo cual no se calculó una muestra probabilística puesto que es un número pequeño de individuos. El instrumento diseñado fue sometido a la validación de expertos. Se calculó su confiabilidadobteniéndose un valor del alpha de Cronbach de 0,76, considerado como aceptable. El procesamiento de los datos permitió obtener las competencias gerenciales requeridas por los cuadros directivos, asi como las competencias de carácter personal y organizacional. Los resultados encontrados se convierten en insumos para el diseño deprogramas de formación, desarrollo y gestión de los directivos universitarios.
Enfoques analíticos y programas educativos para gestionar la convivencia escolar en México
Authors: Chávez Romo María Concepción
Published: July 2019

Este artículo tiene como objetivo recapitular tres modos de acercamiento a la comprensión de lo que sucede en la vida de las escuelas de educación básica en México en relación con el desafío de aprender a vivir juntos: convivencia, disciplina y violencia escolar. Se trata de distintas orientaciones temáticas identificadas en las investigaciones educativas desde los años 1990 que podrían consolidarse como perspectivas analíticas complementarias para comprender la complejidad de los problemas de la convivencia escolar, siempre y cuando su desarrollo sea equilibrado y sistemático. Sin embargo, esto no parece estar sucediendo, al menos en el caso de las investigaciones realizadas en la primera década del siglo XX (entre los años 2002 y 2011) se observa un mayor interés por analizar el fenómeno de la violencia entre estudiantes. Paralelamente, a esta diversidad de acercamientos existen también programas educativos derivados de la actual política educativa que destacan la promoción de ambientes escolares seguros y libres de violencia, pero la mayor parte de las acciones están dirigidas a la prevención y a la reducción de la violencia entre estudiantado, lo cual es relevante destacarlo para valorar los alcances y las limitaciones en la comprensión y transformación de prácticas de convivencia y de resolución de conflictos en las escuelas.
Producción de tomate (Solanum lycopersicum) en invernadero: comparación agronómica entre tipos de tomate
Authors: Monge Pérez José Eladio , Loría Coto Michelle
Published: July 2019

Se evaluaron cuatro tipos de tomate (uva, cherry, cocktail, y gordo), producidos bajo invernadero, a nivel cuantitativo (10 variables). Los datos muestran una amplia variabilidad entre los tipos de tomate en cuanto a edad al inicio de la cosecha (64.8 – 76.5 días después de trasplante), número de frutos por racimo (4.46 – 22.05), número de lóculos por fruto (2.00 – 6.21), peso del fruto (12.41 – 126.80 g), rendimiento (28.17 – 51.18 ton/ha), fi rmeza del fruto (21.34 – 47.13 N), porcentaje de sólidos solubles totales (4.41 – 8.08 °Brix), pH del jugo del fruto (3.73 – 4.02), índice de sabor (70,83 – 131,32), y resultados de la prueba de degustación (1.32 – 2.53 en una escala de 0 a 4). Se concluye que, en comparación con los otros tipos de tomate evaluados, los tomates gordos iniciaron la cosecha en forma más tardía, produjeron menos frutos por racimo, presentaron ,más lóculos por fruto, tuvieron frutos de más peso, produjeron un mayor rendimiento; y sus frutos fueron más fi rmes, tuvieron un menor porcentaje de sólidos solubles totales, y obtuvieron los peores resultados en la prueba de degustación. Con respecto a los tomates uva, cocktail y cherry, las únicas diferencias signifi cativas entre ellos se presentaron en el número de frutos por racimo, la fi rmeza del fruto, el porcentaje de sólidos solubles totales, el pH del jugo del fruto, y el índice de sabor.
KINERJA PEREMPUAN WIRAUSAHA “GUREM” PENERIMA KREDIT
Authors: Safitri Laras Sirly , Suharno Suharno , Jahroh Siti
Published: July 2019

ABSTRAK: Perempuan wirausaha merupakan salah satu faktor kunci pertumbuhan ekonomi, khususnya di perdesaan. Dalam pertumbuhan dan perkembangannya, usaha kecil bahkan skala “gurem” yang dijalankan perempuan seringkali menghadapi hambatan akses terhadap modal. Tujuan dari penelitian ini, untuk menganalisis dampak pemberian kredit melalui pengukuran kinerja usaha perempuan, sebelum dan setelah menerima kredit. Penelitian ini merupakan sebuah aksi yang berbasis pada riset eksperimen. Responden terdiri dari tiga puluh orang yang dipilih secara sengaja (purposive) untuk diberikan perlakuan berupa kredit modal usaha. Hasil analisis menunjukkan bahwa kinerja usaha perempuan penerima kredit belum meningkat setelah menerima kredit. Hal tersebut ditunjukkan oleh tingkat pengembalian kredit yang hanya mencapai 83 persen. Di samping itu, Uji Pangkat Tanda Wilcoxon menunjukkan bahwa tidak terdapat perbedaan omset rata-rata per hari dan marjin keuntungan rata-rata per hari perempuan wirausaha, baik sebelum maupun setelah menerima kredit. Perlu penelitian lanjutan yang dapat  mendesain ulang penyaluran kredit  yang sesuai dengan kondisi dan kebutuhan perempuan wirausaha, serta dilengkapi dengan pendampingan manajemen usaha. Kata kunci: perempuan wirausaha “gurem”, kredit, tingkat pengembalian, omset, marjin keuntungan
Solving Sat in a Distributed Cloud: A Portfolio Approach
Authors: Ngoko Yanik , Cérin Christophe , Trystram Denis
Published: July 2019

We introduce a new parallel and distributed algorithm for the solution of the satisfiability problem. It is based on an algorithm portfolio and is intended to be used for servicing requests in a distributed cloud. The core of our contribution is the modeling of the optimal resource sharing schedule in parallel executions and the proposition of heuristics for its approximation. For this purpose, we reformulate a computational problem introduced in a prior work. The main assumption is that it is possible to learn optimal resource sharing from traces collected on past executions on a representative set of instances. We show that the learning can be formalized as a set coverage problem. Then we propose to solve it by approximation and dynamic programming algorithms based on classical greedy algorithms for the maximum coverage problem. Finally, we conduct an experimental evaluation for comparing the performance of the various algorithms proposed. The results show that some algorithms become more competitive if we intend to determine the trade-off between their quality and the runtime required for their computation.
Lyapunov–based Anomaly Detection in Preferential Attachment Networks
Authors: Ruiz Diego , Finke Jorge
Published: July 2019

Network models aim to explain patterns of empirical relationships based on mechanisms that operate under various principles for establishing and removing links. The principle of preferential attachment forms a basis for the well-known Barabási–Albert model, which describes a stochastic preferential attachment process where newly added nodes tend to connect to the more highly connected ones. Previous work has shown that a wide class of such models are able to recreate power law degree distributions. This paper characterizes the cumulative degree distribution of the Barabási–Albert model as an invariant set and shows that this set is not only a global attractor, but it is also stable in the sense of Lyapunov. Stability in this context means that, for all initial configurations, the cumulative degree distributions of subsequent networks remain, for all time, close to the limit distribution. We use the stability properties of the distribution to design a semi-supervised technique for the problem of anomalous event detection on networks.
Times Series Averaging and Denoising from a Probabilistic Perspective on Time–Elastic Kernels
Authors: Marteau Pierre-Francois
Published: July 2019

In the light of regularized dynamic time warping kernels, this paper re-considers the concept of a time elastic centroid for a set of time series. We derive a new algorithm based on a probabilistic interpretation of kernel alignment matrices. This algorithm expresses the averaging process in terms of stochastic alignment automata. It uses an iterative agglomerative heuristic method for averaging the aligned samples, while also averaging the times of their occurrence. By comparing classification accuracies for 45 heterogeneous time series data sets obtained by first nearest centroid/medoid classifiers, we show that (i) centroid-based approaches significantly outperform medoid-based ones, (ii) for the data sets considered, our algorithm, which combines averaging in the sample space and along the time axes, emerges as the most significantly robust model for time-elastic averaging with a promising noise reduction capability. We also demonstrate its benefit in an isolated gesture recognition experiment and its ability to significantly reduce the size of training instance sets. Finally, we highlight its denoising capability using demonstrative synthetic data. Specifically, we show that it is possible to retrieve, from few noisy instances, a signal whose components are scattered in a wide spectral band.
Accelerating Transformation Program in Indonesian Regional Development Banks: The Importance of High-Quality Information
Authors: Fettry Sylvia , Djajadikerta Hamfri , Lusanjaya Gery Raphael
Published: July 2019

Objective – The role of Indonesia Regional Development Bank (RDB) as an agent of development in each specific operational area is expected to give a significant contribution to regional economics. The Transformation Program in Indonesian RDB started since 2015 is created to optimize the RDB’s role. This study is aimed to gain some description about the level of information quality in Indonesian RDB, to obtain real situation on the implementation of Transformation Program in Indonesian RDB, and to test whether the high-quality information will accelerate the implementation of Transformation Program in Indonesian RDB.Design/methodology – The study was conducted using data from the annual report of Indonesian RDBs and additional in-depth interview with RDB practitioners. The technique of purposive sampling is used in this study with the data availability criteria. The statistic analysis uses multiple regression with t-test and F-test to test the influence of information quality and some control variables on the implementation of Transformation Program in Indonesian RDB. Results – The Indonesian RDBs’ quality of information still cannot be perceived at a high level. The implementation of Transformation Program in Indonesian RDBs has already run in the first phase of foundation building with various obstacles. The high-quality information produced by financial reporting of RDB is proven can accelerate the implementation of Transformation Program in Indonesian RDBs. Research limitations/implications – The theoretical contribution of this study is giving empirical evidence that the information quality accelerates the implementation of Transformation Program in Indonesian RDB. The managerial  implication is that Indonesian RDBs must improve their financial reporting system and create some innovations for the successful Transformation Program. The main limitation of this research is the limited scope of study. It is recommended to make further relevant research on the same issue in a wider context to get more enriched findings.Novelty/Originality – The area of implementation of Transformation Program in Indonesian RDBs has been insufficiently examined currently. Thus, this study contributes to this area by examining whether high-quality information produced by financial reporting will accelerate the implementation of Transformation Program in Indonesian RDB.Keywords Information Quality, Financial Reporting, Banking Transformation.
EDITORIAL BOARD
Authors: Board Editorial
Published: July 2019

editorial board
Peramalan Indikator Mikro Kinerja Komoditas Strategis Perkebunan Dengan Metode ARIMAX (Autoregressive Moving Average Exogenous Variabel)
Authors: Kharisma Bayu
Published: July 2019

This paper aims to forecast various micro indicators of the performance of plantation strategic commodities, namely coffee, cocoa, pepper and sugar cane in Indonesia during the period 2019-2045. The methodology used in this paper is ARIMAX (exogenous autoregressive variable moving average). The results showed that pepper production tended to decrease. The same thing happened in the prediction of the area of ??pepper land which tended to continue to decline, while pepper productivity was relatively stable. Meanwhile, the projection of coffee commodity production, coffee area and productivity levels continue to rise. The projection of sugarcane production tends to increase despite fluctuations. Similar to the pattern of production, the area of ??sugarcane and productivity also increased. The projection of Indonesian cocoa production fluctuates and tends to increase during 2019-2045. The same conditions occur in the area of ??cocoa that continues to increase. Finally, the level of cocoa productivity is rising even though it tends to be volatile.
Penilaian kualitas visual dan aspek sapta pesona pada lanskap Bali Zoo di Desa Pakraman Singapadu, Gianyar
Authors: Kurniawan I Kadek Ari , Sugianthara Anak Agung Gede , Astiningsih Anak Agung Made
Published: July 2019

Assessment of the Visual Quality and Sapta Pesona Aspect on Bali Zoo Landscape in Singapadu Traditional Village, Gianyar. Bali Zoo is one of the artificial landscapes in the form of a zoo with educational, conservation, and tourism functions. This zoo has a vision to make Bali Zoo as an international zoo standards. Some efforts that can be done to realize the vision is by improving the aesthetic quality and aspects of sapta pesona. The assessment of visuals quality and aspects of sapta pesona in Bali Zoo aims to evaluate both visuals quality and sapta pesona aspect in the Bali Zoo landscape. Methods used in this research was field survey with observation, questionnaire, interview, and literature review techniques. The result was a description of the assessment of visuals quality and aspects of sapta pesona on Bali Zoo landscape, therewith recommendation that can be given in the form of recommendation might improve the visuals quality and aspects of sapta pesona on Bali Zoo landscape. It is concluded that the visuals quality and aspects of sapta pesona on Bali Zoo landscape were quite good and it can improve the aesthetic visuals quality of Bali Zoo landscape by improving the quality of landscape elements, whereas improving the aspects of sapta pesona from the elements of security, discipline, hygiene, beauty, coolness, friendliness, memory. These recommendation was suitable to apply by the manager, visitors and students.
Pemahaman dan Kepedulian Penerapan Green Accounting: Studi Kasus UKM Tahu Tempe di Kota Bandar Lampung
Authors: Pentiana Destia
Published: July 2019

The general objective of this study is to find out whether: 1) the SMEs of tofu and tempe in Bandar Lampung city have knowledge of the concept of green accounting 2) the SMEs of tofu and tempe in Bandar Lampung city care about the environment. The type of data used in this study is primary data, namely by interviewing and distributing questionnaires to the businessmen of tofu and tempe in Bandar Lampung city. Based on the results of the questionnaire, it was found that the understanding of the perpetrators of SMEs of tofu and tempe in Bandar Lampung city is still low because the preference of the interests of the actors of SMEs of tofu and tempe is still focused on operating profits not on product quality and environmental quality. The lack of awareness of environmental impacts that can affect the sustainability of its business is a factor that causes the low level of understanding. In terms of knowledge of the environmental costs, SMEs is also identified low. This is because the business actors are unable to identify what constitutes the components of environmental costs which also become a factor that causes low understanding of the SMEs. Keywords: Green Accounting, Environmental Costs, SMEs.
Menemen Koşullarında Pamuk Yetiştiriciliğinde Uygulanan Farklı Toprak İşleme Yöntemlerinin Enerji Verimliliği ve Kullanım Etkinliğinin Belirlenmesi
Authors: TOPDEMİR Tuncay , COŞKUN Mustafa Bülent
Published: July 2019

Bu çalışmada pamuk üretiminde farklı toprak
işleme yöntemlerinin uygulandığı parsellerin enerji ve maliyet analizleri
üzerine araştırma yapılarak, üretimdeki girdilerin birim alan başına enerji
eşdeğerleri, elde edilen ürünün enerji verimliliği, toplam maliyet ve kar
değerleri hesaplanmıştır. Araştırmada kullanılan veriler, dört farklı yöntemde
3 tekerrürlü olarak yürütülen deneme parsellerinden elde edilmiştir.

Çalışmada en yüksek enerji girdisi geleneksel
toprak işleme yönteminde, en düşük enerji girdisi ise doğrudan ekim yönteminde
gerçekleşmiştir. Enerji çıktıları incelendiğinde ise en yüksek enerji çıktısı
verimin en yüksek olduğu geleneksel toprak işlemede en düşük enerji çıktısı da
verimin en düşük olduğu doğrudan ekim yönteminde gerçekleşmiştir. En yüksek
enerji oranı 4.38 ile geleneksel toprak işleme konusunda, sonra sırasıyla 3.99
ile azaltılmış toprak işleme 2 konusunda, 3.93 ile doğrudan ekimde
gerçekleşmiştir. En düşük enerji oranı ise 3.72 ile azaltılmış toprak işleme 1
konusunda hesaplanmıştır.
A De Novo Molecular Generation Method Using Latent Vector Based Generative Adversarial Network
Authors: Prykhodko Oleksii , Johansson Simon Viet , Kotsias Panagiotis-Christos , Bjerrum Esben Jannik , Engkvist Ola , Chen Hongming
Published: July 2019

Recently deep learning method has been used for generating novel structures. In the current study, we proposed a new deep learning method, LatentGAN, which combine an autoencoder and a generative adversarial neural network for doing de novo molecule design. We applied the method for structure generation in two scenarios, one is to generate random drug-like compounds and the other is to generate target biased compounds. Our results show that the method works well in both cases, in which sampled compounds from the trained model can largely occupy the same chemical space of the training set and still a substantial fraction of the generated compound are novel. The distribution of drug-likeness score for compounds sampled from LatentGAN is also similar to that of the training set.
Aplikasi Kamus Bahasa Jawa Ngoko, Jawa Krama, dan Indonesia Berbasis Android Dengan Menggunakan Metode Sequential Search
Authors: Shiddiq Ibnu Fajar , Witanti Arita
Published: July 2019

Proses pencarian kata kamus berupa buku dapat memakan waktu yang cukup lama karena proses pencariannya secara manual. Sehingga perlu dibuat suatu aplikasi, salah satunya yaitu aplikasi kamus digital yang dapat mempermudah dalam pencarian kata dan tidak perlu mengeluarkan biaya tambahan untuk membeli kamus.Penelitian ini bertujuan untuk membuat aplikasi kamus tiga bahasa yaitu bahasa Jawa Ngoko, Jawa Krama dan Indonesia berbasis Android dengan menggunakan metode Sequential Search, dimana metode pencarian ini dengan cara pengurutan dari indexawal hingga data yang ditemukan. Dalam penelitian ini menggunakan perangkat lunak Eclipse sebagai perangkat lunak pembuatan aplikasi dan SQLite sebagai media penyimpanan data kamus.Adapun hasil dari penelitian ini yaitu berupa aplikasi kamus Bahasa Jawa Ngoko, Jawa Krama, dan Indonesia dengan menggunakan metode Sequential Search. Dalam metode ini mampu melakukan pencarian kurang-lebih 2730 kata dan tingkat keakuratan setiap pencarian 100%. Dalam proses pencarian data yang dapat membantu pengguna dalam memahami dan mempelajari bahasa Jawa - Indonesia ini memerlukan rata-rata 0.5 detik setiap pencariannya.
Identifikasi Mangga Harum Manis Karbitan dan Tidak Karbitan Dengan Learning Vector Quantization
Authors: Puspitaningrum Wahyu , Supatman Supatman
Published: July 2019

Buah mangga memiliki banyak jenis salah satunya adalah  mangga  harum manis. Kematangan buah mangga arum manis ada yang alamiah atau melalui proses pengkarbitan. Karbit adalah kepanjangan dari kalsium karbida. Karbit biasanya digunakan dalam proses las karbit dan juga dapat mempercepat pematangan buah.Pengambilansampledilakukan pada dua jenis kematangan mangga harum manis yaitu mangga harum manis karbitan dan tidak karbitan. Pengembanganalgoritma yang dilakukan bertujuan untuk mengidentifikasi mangga harum manis yang dapat membedakan kematangan mangga karbitan dan tidak karbitan menggunakan Learning Vector Quantization(LVQ). Ciri yang digunakan untuk mengidentifikasi citra mangga adalah rata-rata, varian dan standar deviasi.Jumlah data pelatihan yang digunakan terdiri dari 2 kelas(kelas 1: mangga karbitan, kelas 2: mangga tidak karbitan), dan masing-masing kelas berjumlah 30 data pelatihandengan total data berjumlah 60 data pelatihan. Sedangkan untuk data uji masing-masing kelas menggunakan 25 data uji dengan total berjumlah 50 data uji.Pada proses pelatihan menggunakan parameter LVQ (alfa0.001 dengan dec alfa0.9) diperoleh unjukkerja terbaik sebesar 98.33%. Bobot akhir yang diperoleh dari unjukkerja terbaik pada pelatihan digunakan untuk melakukan pengenalan. Unjuk kerja terbaik dari 50 data uji mencapai 98%dengan perincian 96 % mangga karbitan dan 100 % mangga tidak karbitan.
Population, Migration, and Generations in Urban Neighborhoods
Authors: Whitaker Stephan D.
Published: July 2019

The number of people living in urban neighborhoods has been rising in recent decades. This Commentary investigates changes in the number, ages, and financial status of those who have been moving into and out of urban neighborhoods, using data from the Federal Reserve Bank of New York/Equifax Consumer Credit Panel. I find that since 2000, the increase in urban populations is the result of young adults migrating into urban neighborhoods and senior citizens aging in place. Urban populations have also become more educated and well to do. While declining urban neighborhoods may still outnumber growing urban neighborhoods within some regions, urban leaders there can work toward population or tax base growth knowing that consumer tastes and national trends are favorable to those goals.
Formas e Definições de Mediação Cultural no Campo da Museologia e suas diferentes aplicações
Authors: Carvalho Letícia Ferreira de , Miranda Larissa Caroline De Oliveira , Rocha Eliane Cristina De Freitas
Published: July 2019

O presente artigo busca melhor compreender de que maneira o termo mediação cultural vem sendo trabalhado dentro do campo da Museologia. Para isso, foi realizado um levantamento das diferentes formas de mediação cultural presentes na literatura da área a partir de artigos de revistas de classificação A1 a B3 encontradas na plataforma Qualis da Capes, num recorte de 10 anos (2007-2017). Foram analisados 63 artigos sobre a temática, dos quais apenas quatro abordaram experiências de mediação cultural de uma perspectiva horizontal, as quais são apresentadas e discutidas.
Hugues de Varine e os museus comunitários no Brasil
Authors: Santos Jr. Roberto Fernandes dos , Britto Clovis Carvalho
Published: July 2019

Entrevista realizada com Hugues de Varine em 22 de janeiro de 2017 visando explicitar aspectos de sua trajetória, pensamento e relação com os museus e a Museologia Comunitária no Brasil. Ao privilegiar essa temática, a entrevista se torna fonte significativa para a visualização de um mapeamento de iniciativas comunitárias que o consultor francês integrou no campo dos museus, da Museologia e do Patrimônio no Brasil.
Sobre l’audiència del Curial e Güelfa
Authors: Butinyà Júlia
Published: July 2019

En una obra anònima és primordial d’ajustar al màxim l’audiència. La novel·la Curial e Güelfa hi ha tingut diferents propostes, generalment al voltant de la cort del Magnànim.

Ací, arran d’aquestes observacions i davant la situació científica actual, comptant com a referents amb la recent investigació d’Abel Soler i també la meva —30 anys anterior—, hi afegeixo un nou destinatari i reflexiono sobre les conseqüències que implica.
Sant Vicent Ferrer i la «nació» dels valencians (c. 1350-1419)
Authors: Baydal Sala Vicent
Published: July 2019

A grans trets, els estudis d’Antoni Ferrando, Enric Guinot, Agustín Rubio Vela i Vicent Baydal han perfilat una cronologia bastant detallada del procés de formació de la identitat col·lectiva valenciana vinculada al Regne de València durant la baixa edat mitjana. El present article profunditza en el període d’existència del dominic Vicent Ferrer (c. 1350-1419), durant el qual es va produir la irrupció amb potència en l’esfera pública dels principals usos i funcions de la identitat col·lectiva valenciana.
PRODUCCIÓN Y EXTRACCION DE ACEITE DE ORÉGAN (Lippia graveolens Kunth) BAJO CULTIVO EN LA COMARCA LAGUNERA
Authors: Flores Hernández Arnoldo , Hernández Herrera José Antonio , López Medrano J. Ignacio , Valenzuela Núñez Luis Manuel , Martínez Salvador Martín , Madinaveitia Ríos Héctor
Published: July 2019

México es el principal exportador de orégano a escala mundial. En este estudio fueron evaluadas la producción y extracción de aceite (cocción y arrastre con vapor) de plantas de Lippia graveolens cultivadas bajo tres grados de humedad (alto: 3 /3 C. C., medio: 2/ 3 C. C y bajo: 1 /3 C. C.) y un testigo (silvestre). Se tomaron seis muestras de tres bloques por cada tratamiento de humedad a las cuales se les midió altura, cobertura, número de ramificaciones, peso fresco, peso seco y materia seca útil (producto). Los resultados mostraron diferencias significativas superiores en las variables consideradas en las plantas bajo cultivo, con respecto a las silvestres. Sin embargo, la parte vegetal útil de los individuos en condiciones de riego es afectada por la mayor altura, cobertura y número de ramas. Así mismo con el tratamiento de humedad de 2 /3 de la capacidad de campo del suelo, se obtuvo el mejor resultado. En cuanto al método de extracción de aceite, el de arrastre con vapor de agua fue significativamente superior en rendimiento de aceite (mL) y porcentaje en comparación con el método tradicional por cocción. El orégano bajo cultivo presentó mayor producción de follaje y parte útil, así como del contenido de aceite, en relación al silvestre.
PENGARUH POSITIF PARIWISATA TERHADAP KEPUASAN HIDUP DAN NILAI CO CREATION (STUDI PADA KOMUNITAS LINGKAR KEK MANDALIKA)
Authors: Rinuastuti Baiq Handayani
Published: July 2019

Memahami perilaku penduduk terkait dampak pariwisata serta akibat dari dampak tersebut menjadi hal yang penting untuk dikaji dalam upaya pengembangan pariwisata di masa yang akan datang. Tujuan dari penelitian ini adalah untuk menganalisis dampak positif pariwisata yang dirasakan penduduk di Kawasan Ekonomi Khusus Mandalika yang dapat memengaruhi kepuasan hidup mereka serta kesediaan penduduk untuk menciptakan nilai bersama (co-creation value) dengan wisatawan. Hasil penelitian menunjukkan bahwa pengaruh positif dari kegiatan pariwista serta kepuasan hidup secara signifikan berpengaruh terhadap nilai Co Creation, namun dampak positif pariwisata berpengaruh tidak signifikan terhadap kepuasan hidup.  Hasil penelitian ini diharapkan dapat berkontribusi pada perkembangan teori khususnya pemasaran pariwisata dari perspektif penduduk lokal. Selain itu dapat dijadikan dasar pertimbangan para pengambil kebijakan dalam pengembangan dan pemasaran pariwisata kawasan Ekonomi Khusus Mandalika Kata kunci : Dampak posistif pariwisata, kepuasan hidup, co-creation value, KEK Mandalika
Bahan Ajar IPA Berbasis Inkuiri Terstruktur Untuk Meningkatkan Literasi Sains Peserta Didik SMP
Authors: Hasanah Jamiatul , Jamaludin Jamaludin , Prayitno Gito Hadi
Published: July 2019

Penelitian ini bertujuan untuk mengembangkan bahan ajar IPA berbasis inkuiri terstruktur untuk meningkatkan literasi sains peserta didik SMP pada materi sistem gerak makhluk hidup. Prosedur penelitian yang digunakan adalah model Dick & Carey. Pada tahap evaluasi formatif dilakukan melalui validasi bahan ajar oleh tiga orang ahli dan satu orang praktisi, uji coba terbatas terhadap bahan ajar IPA yang dilakukan di kelas VIII, dan uji validitas dan reliabelitas instrument tes literasi sains yang dilakukan di kelas IX. Aspek kelayakan yang dinilai oleh keempat validator terhadap bahan ajar IPA yang dikembangkan yaitu materi dan desains produk.ÃÂ  Persentase rata-rata nilai kelayakan dari keempat validator yaitu aspek materi 80,7% dan aspek desain produk 80,9%. Penggunaan bahan ajar IPA pada uji coba terbatas mendapatkan respon praktis dari guru kelas VIII dengan rata-rata skor 80,0% dan respon sangat praktis dari peserta didik dengan rata-rata skor 84,0%. Hasil uji validitas dan reliabilitas instrument tes literasi sains menunjukkan bahwa dari 15 soal dinyatakan 10 soal valid (r> 0,338) dan reliebel CronbachÃ¢â¬â¢s Alpha > 0,338.ÃÂ ÃÂ
ANALISIS PENETAPAN DAN PENGEMBANGAN PRODUK UNGGULAN HORTIKULTURA KABUPATEN TUBAN TAHUN 2015
Authors: Patiung Markus
Published: July 2019

ABSTRAKPenelitian ini dengan judul Analisis Penetapan dan Pengembangan Produk Unggulan Hortikultura Kabupaten Tuban adalah membuat Mendapatkan deskripsi potensi produk unggulan hortikultura di Kabupaten Tuban. Mengetahui dan menganalisis  apa saja faktor pendorong dan faktor penghambat yang berpengaruh terhadap pengembangan potensi produk unggulan hortikultura di Kabupaten Tuban. Merumuskan road map strategi pengembangan potensi produk unggulan hortikultura di Kabupaten Tuban.Metode yang Penelitian ini dilaksanakan dengan metode analisis deskriptif, yaitu menggambarkan kondisi obyek penelitian apa adanya. Metode analisis bersifat kualitatif dan kuantitatif. Secara deskriptif kuantitatif, digunakan alat analisis yaitu : analisis Tipologi Klassen, Analisis Location Quotient (LQ), Analisis Matriks SWOT, dan Analisis EFAS/IFAS. Hasil Penelitian Analisis Penetapan dan Pengembangan Produk Unggulan Hortikultura Kabupaten Tuban antara lain: Kontribusi subsektor tanaman hortikultura dalam PDRB Kabupaten Tuban yaitu sebesar 0,51 persen dan tumbuh sebesar 2,99 persen pertahun, dalam periode lima tahun terakhir (2010-2014). Oleh karena itu peningkatan peningkatan produksi dan kualitas komoditi hortikultura menjadi sangat penting. Pertumbuhan produksi yang rendah dan cenderung menurun dari tahun ketahun di Kabupaten Tuban dipengaruhi oleh beberapa hal antara lain: menurunnya jumlah rumah tangga pertanian dalam periode 2003-2013 sebanyak 14,5 persen, kurangnya upaya pemasaran buah dan sayur unggulan, dan kurangnya perhatian pemerintah daerah melalui program dan kegiatan yang ada selama ini. Penurunan ini ditunjukkan secara kuantitatif dengan banyaknya komoditi yang masuk dalam klasifikasi potensial. Produk unggulan hortikultura Kabupaten Tuban pada tahun 2015, berdasarkan analisis Tipologi Klassen, LQ  dan AHP adalah Cabe Besar, Cabe Rawit/Kecil, Belimbing, Mangga, Melon, Semangka, Duku, Jeruk, Pisang dan Jambu Biji. Produk unggulan yang telah ditetapkan pemerintah daerah atau nasional seperti Duku Prunggahan, Belimbing Tasikmadu dan Jeruk Keprok Tejakula membutuhkan perhatian yang lebih besar agar meningkat produksi dan produktivitasnya di masa depan. Pemasaran merupakan faktor yang paling utama dalam menghambat peningkatan produksi dan nilai ekonomi produk unggulan, selain karena karakteristik dan kesesuaian agroklimat dan agrosistem di Kabupaten Tuban.Kata kunci : LQ, Klassen, SWOT.
Analisis Pelaksanaan Penanggulangan Kemiskinan Kota Kediri Tahun 2015
Authors: Hermawati Diah Tri
Published: July 2019

ABSTRAKPenelitian ini dengan judul Analisis Pelaksanaan Penanggulangan Kemiskinan Kota Kediri Tahun 2015 bertujuan untuk menjelaskan kinerja TKPK Kota Kediri dalam menyelenggarakan tugas koordinasi penanggulangan kemiskinan dan pengendalian pelaksanaan program penanggulangan kemiskinan di daerah, menjelaskan pelaksanaan kebijakan (program, anggaran dan regulasi) penanggulangan kemiskinan di daerah dan menjelaskan pencapaian daerah dalam penanggulangan kemiskinan.          Dalam pelaksanaan penelitian ini metode yang digunakan yaitu dilakukan pengumpulan data di wilayah administrasi Pemerintah Kota Kediri dengan menggunakan subyek data yang paling dapat dipercaya (valid) dan terbarukan (update) yang dimiliki daerah bersangkutan.Hasil Penelitian ini menyimpulkan bahwa sampai dengan tahun 2013, capaian prosentase penduduk miskin di Kota Kediri (sebesar 8,20%), masih jauh dari target pencapaian RPJMN maupun target MDG’s yang mencanangkan capaian minimal 8% pada tahun 2014. Capaian prosentase penduduk miskin Kota Kediri pada tahun 2013, masih di atas (lebih buruk) capaian di tingkat Propinsi Jawa Timur (12,73%) maupun rata-rata capaian secara Nasional (10,96%) pada tahun yang sama; Perkembangan capaian prosentase penduduk miskin di Kota Kediri selama 5 tahun terakhir (2009-2013) menunjukkan trend perkembangan yang menurun (semakin membaik) meskipun capaian pada tahun 2014 sedikit meningkat dibanding tahun 2013; Capaian indeks kedalaman kemiskinan dan indeks keparahan kemiskinan pada tahun 2013 masing-masing adalah 1,60% dan 0,47%. Capaian keduanya di bawah capaian di Provinsi Jawa Timur maupun Nasional. Perkembangan capaian keduanya selama 5 tahun terakhir (tahun 2009-2013) menunjukkan trend perkembangan yang semakin membaik.Kata kunci : Kemiskinan, RPJMN, MDG’s.