bluuebunny/crossref_metadata_2025 huggingface dataset:
Determinants of Leadership in Improving Sound Governance in South Regional State Education Sector, Ethiopia
Authors: Lerra Mulatu Dea
Published: January 2024

This study aimed to identify the determinants of leadership in improve sound governance in education sector institutions of the South Nation Nationalities People Region (SNNPR). The study was used a quantitative method (QUAN). It used inferential approach for their appropriateness for defining the research problem. The survey questionnaire collected from 660 participants purposefully and randomly selected from the nine zones, nine Woredas, and nine town administrations sampled education institutions of the SNNPR. Multistage sampling techniques (purposive, random sampling techniques) were instrumental. The logit model and multicollinearity effect were employed were instrumental.  It has been found that sampled education sector institutions were experiencing various leadership determinants that hindered the promotion of sound governance, on the logit model.  It can be concluded that, despite some policy initiatives and directives introduced by the regional government, the study identifies various determinants of leadership that effecting the promotion of sound governance. The researcher, thus, specified some significant policy implications to promote sound governance in SNNPR education sector institutions: establish strong accountability mechanism, granting autonomy, strengthening anti-corruption agencies and law, promoting management development program, promoting equity and fairness institutionalizing transparency system, trans, revisit policy directives and initiatives, promoting integrity, the merit-based nomination of education officials and adopt empowerment and management programs are some of the policy implications
The Influence of Educational Leadership in Successful Change Management in Education Office of Wolaita Zone
Authors: Lerra Mulatu Dea
Published: January 2024

This study aimed to examine the influence of educational leadership in successful change management in Wolaita zone some selected woreda education offices. The target populations for this study were from Wolaita zone woreda educational offices. In Wolaita zone, there are 22 woredas/districts and 3 city administrations; among them three woreda education offices and one city administration education office were selected through simple random sampling and purposive sampling respectively. Therefore, total population of the study was 230; among them   63 expertise, 6 educational office leaders, 40 supervisors and 121 principals were selected by purposive sampling method. In order to collect data, questionnaires, was employed. This study was carried through descriptive survey design. The study revealed that the leader’s ability to influence the followers was poor and leaders not playing their leadership role appropriately. The finding also shows strong effect of leadership on successfully implementing change management process in the sampled study areas. Thus, one can recommend that leaders should motivate follower and change agent by being role mode land participatory. The leaders should develop and institutionalize appropriate strategy to implement change in the institutions.
A Perceptual Leadership Style for The Philippine Airline Management: An Initial Survey
Authors: Rioveros Gilmore M.
Published: January 2024

The research was an initial survey of the diverse types of leadership used by notable people across the globe. This qualitative study analyzed these leadership styles and the relevance of leadership at work. There were several styles listed, but the researcher has found one style to be appropriate in the management of the Philippine Airlines. This study utilizes observation and documentary analysis. As a result of this paper, it was found out that the best model for leadership that can be used is the transformational model  which is also the leadership of the transition or transformational leadership. In order to confirm its usefulness and relevance for the good of the organization or business, the researcher will prefer to perform an extensive analysis on transformational leadership in the future.
Effects Euphrates river flow variation in Geographical distribution sand Minerals and path the weathering from AL Baghdadi city to AL Fallujah city
Authors: Aftan Laith saadi
Published: January 2024

Petrographic study Minerals of very fine sand were carried in two terraces of Euphrates river. which starting from AL Baghdadi in the Northwest to- AL Fallujah in the East south. the study were including petrography characterization of light and heavy minerals. The aims of this study to know the ratio of minerals and spatial geographical distribution as well as to explain the effect of the Euphrates river in this distributed and weathering state. The results of this study showed; Convergence ratio of light and heavy minerals in all terraces ancient and modern. The weathering of light minerals increased in the old desert terraces. The heavy minerals (Rutile) showed the pedo stratigraphy between the modern and ancient terraces on the long the path.
Does Emotional Intelligence Prompt Knowledge Sharing Behavior among Academic Staff
Authors: Hatamleh Dr. Amer
Published: January 2024

The presented paper aims to reveal the direct and indirect relationship between emotional intelligence and knowledge sharing behavior among academic staff in Jordanian universities. Furthermore, it aims to examine the mediation effect of knowledge sharing intention on the relationship between emotional intelligence and knowledge sharing behavior. Convenience sampling was used to collect data from 191 academic staff from private universities in the northern region of Jordan. First, data were tested for validity and reliability. Second, Structural Equation Modeling (SEM) was applied to analyze the model and hypothesis testing. The results indicated that emotional intelligence has a direct and indirect relationship with academic staff knowledge sharing behavior. Furthermore, the results indicated that knowledge sharing intention partially mediates the relationship between emotional intelligence and academic staff knowledge sharing behavior. The limitations of this study include the sampling and cross-sectional design. Hence, future studies can be conducted using a longitudinal design covering other public universities to increase the generalizability of findings. The findings suggest that top management in universities should develop appropriate strategies for improving the emotional intelligence level of academic staff because academic staffs with higher emotional intelligence are more likely to engage themselves in knowledge sharing activities. Furthermore, universities should conduct various training and education programs to improve the level of emotional intelligence among academic staff, thereby fostering knowledge sharing in universities. Furthermore, there is limited literature on the role of emotional intelligence in knowledge sharing behavior among academic staff. The study adds to the extant literature on emotional intelligence and both knowledge sharing intention and knowledge sharing behavior in the context of universities. Besides, the study attempted to investigate the direct and indirect effect of emotional intelligence on knowledge sharing behavior that has not been studied so far.
Diagnostic criteria of endothelial dysfunction, subclinical atherosclerosis and their relationship with NOS3 and HIF1A gene polymorphism in military personnel in extreme conditions of the arctic zone
Authors: Lemeshchenko Alexei V. , Gurina Olga  I. , Tsygan Vasiliy N. , Makarov Andrey B. , Krivolutskaya Tatiana A. , Berg Dmitriy V. , Kirillov Alexey S.
Published: January 2024

The state of the arterial vascular endothelium against the background of subclinical atherosclerosis and its relationship with gene polymorphism in military personnel serving in the Arctic climatic zone, depending on the duration of service, was evaluated. In total, 251 male servicemen aged 28–40 years were examined. The group of servicemen of the Arctic climate zone included 99 people, who were divided into three groups according to the duration of military service in the Arctic: group 1 included 8 (8%) servicemen with up to 5 years of military service; group 2, 21 (21%) people with 5–10 years; group 3, 70 (71%) servicemen with 10 years. The control group included 152 military personnel aged 28–40 years from the temperate climate zone. All participants underwent a test with reactive hyperemia, elastography, measurement of the thickness of the intima–media complex on the brachial artery, ultrasound examination of the common carotid arteries, photoplethysmography, pulse oximetry, spirometry, anthropometry, biochemical blood analysis, and determination of gene polymorphism using polymerase chain reaction. The results revealed that endothelium-dependent vasodilation rats in groups 2 and 3 were 1. 7 and 2. 7 times less than that in group 1 (p 0. 05). In 11 (16%) military personnel of group 3, thickening of the intima–media complex was found in 50% of the adjacent areas of the common carotid arteries. In groups 2 and 3, the total blood cholesterol level exceeded the value by 10% and 14%, respectively, compared with group 1 (p 0. 05). The artery wall was rigid in carriers of the T/T genotypes of the HIF1A and NOS3 genes and was most elastic in the G/T genotypes of the NOS3 gene and C/C of the HIF1A gene. In general, military personnel serving in the Arctic climatic zone with a service duration of 10 years have endothelial dysfunction and peripheral vascular stiffness with subclinical atherosclerosis phenomena, particularly in military personnel with the T/T genotypes of HIF1A (rs11549465) and NOS3 (rs1799983). We believe that the leading pathogenetic link of endothelial dysfunction of arterial vessels is the resistance of myocytes to the effects of vasodilation factors expressed by the vascular endothelium, particularly nitric oxide. The longer the service experience of military personnel under conditions of polar hypoxia, the higher the probability of developing endothelial dysfunction.
Clinical significance of behavioral type “a” in patients suffering from rheumatoid arthritis
Authors: Yudin Vadim A. , Odin Vitaly I. , Kuvshinnikov Alexander V. , Inamova Oksana V. , Zhigulina Angelina I. , Tyrenko Vadim V.
Published: January 2024

According to modern concepts, rheumatoid arthritis is a classic psychosomatic disease that leads to a decrease in the quality of life of patients and their early disability. To date, few foreign and domestic studies have examined the relationship between behavioral type “A” and rheumatoid arthritis. The clinical significance of behavioral type A in patients with rheumatoid arthritis has been studied to determine new therapeutic and diagnostic approaches. As part of a one-stage (cross-sectional) study, 74 people suffering from rheumatoid arthritis were examined during the year, which were represented by two groups, in accordance with the diagnosed behavioral type. The first group consisted of 22 patients suffering from rheumatoid arthritis with behavioral type A, and the second group consisted of 52 patients suffering from rheumatoid arthritis with behavioral type B. All patients received standard basic and anti-inflammatory therapy in the form of methotrexate at a dose selected individually. The duration of adequate basic therapy corresponded to the incidence of rheumatoid arthritis in both groups. Patients with behavioral type A were characterized by lower immunological activity, manifested, among other things, by a lower level of antibodies to cyclic citrullinated peptide and C-reactive protein, whereas the frequency of erosive lesions was higher. The presence of behavioral type A in patients with rheumatoid arthritis is a risk factor for the development of atherosclerotic damage. A personal negative quality, i. e. , hostility, which is included as one of the characteristics of behavioral type “A,” has a reliable direct relationship with the number of erosions, and significantly, its value directly correlates with the incidence of rheumatoid arthritis. Thus, the stratification of patients suffering from rheumatoid arthritis, according to the presence of behavioral type “A,” demonstrates the clinical and laboratory features of the disease and may be important for the development of new therapeutic and diagnostic approaches and the provision of therapeutic and preventive interventions in these patients
Features of the epidemiological surveillance system of rabies and monkeypox in the Republic of Cameroon
Authors: Yumba Е. Е.К. , Kuzin Aleksandr A. , Zobov Andrey E.
Published: January 2024

The prevention and control of zoonotic infections remain a problem in most countries. However, this problem has become particularly relevant in recent decades, when the occurrence and pandemic spread of zoonotic diseases have become more frequent. All spheres of the national economy that ensure the fight against infections of this group (healthcare systems, veterinary medicine, and ecology) are trying to jointly find appropriate solutions to ensure antiepidemic protection of the population by taking adequate measures to prevent and combat infectious zoonoses. According to the World Health Organization, the spread of zoonotic infections is observed on all continents, particularly in Asia and Africa. The epidemiological significance of zoonoses depends on their effects on the population (morbidity and mortality), their ability to overcome interspecific barriers, and the individual characteristics of pathogens. It is also influenced by factors such as geographical location, climate, population density, economic growth rates, and development level of private and industrial livestock and poultry farming. The epidemiological surveillance systems in Cameroon are compared with the surveillance system in Russia and with the standards set by international organizations such as the World Health Organization and the Food and Agriculture Organization of the United Nations. The emergence and spread of current zoonotic infections in the Republic of Cameroon are presented. The study showed the geographical, social, administrative, economic, and health characteristics of Cameroon, which may influence the emergence and spread of infectious zoonosis in the country. Zoonotic diseases have only begun to receive special attention in Cameroon’s health system in 2014–2016, following an outbreak of monkeypox (mpox) in Cameroon. Moreover, the study described the epidemiological surveillance system and a classification of epidemic events monitored by the Cameroon Disease, Epidemic and Pandemic Control Authority. In general, the surveillance system for human and animal zoonoses in Cameroon was designed to ensure a rapid response during an epidemic. However, some shortcomings exist, such as low data for some zoonotic diseases and insufficient or virtually nonexistent surveillance in some regions of the country. To intensify the fight against the epidemic spread of these zoonotic infections, the capacity of health workers and technical means for detection and monitoring must be improved. The update of the national vaccination schedule should consider diseases such as rabies, given its endemic nature in the country; this may be possible through the establishment of a service or office responsible for surveillance, detection, and response to infectious zoonotic diseases.
Blood coagulation system in experimental acute lung injury and its treatment with dexamethasone
Authors: Voloshin Nikita I. , Chuchalin Evgeny O. , Pugach Victoria A. , Salukhov Vladimir V. , Tyunin Mikhail A. , Kharitonov Mikhail A. , Rudakov Yuri V. , Minakov Alexey A. , Goverdovskiy Yuriy B. , Belyakova Tatyana A. , Kochukova Viktoriya V.
Published: January 2024

The effects of short- and long-term administrations of dexamethasone on survival, severity of pulmonary edema, and hemostasis on experimental lipopolysaccharide-induced acute lung injury in rats were analyzed. Acute lung injury in rats was modeled by the intratracheal injection of lipopolysaccharide from the Salmonella enterica cell wall. White male rats were randomly divided into nine groups: the intact group consisted of 10 animals; two control groups of 20 animals each, in which acute lung injury was simulated without further treatment and removed from the experiment on day 3 or 7; six comparison groups of 20 animals each, in which, 3 h after modeling of acute lung injury and then once a day for 3 days (short mode of administration) or 7 days (long mode of administration), dexamethasone solution was administered intraperitoneally in the following doses: 0. 52 (equivalent to 6 mg/day for humans), 1. 71 (20 mg/day for humans), and 8 mg/kg/day (94 mg/day, pulse therapy for humans). On days 3 and 7, the survival rate, coagulogram values (active partial thromboplastin time, prothrombin time, activity of antithrombin, and soluble fibrin monomer complexes), and low-frequency piezotromboelastography data were assessed in the surviving animals. The results revealed that dexamethasone reduces mortality in acute lung injury and has a dose-dependent effect on the hemostasis system: with an increase in the dose administered, blood clotting processes increase and fibrinolysis is inhibited. Low-frequency piezothromboelastography with a conventional coagulogram allows for a comprehensive assessment of the hemostasis system, identifying violations, and timely drug correction.
Effect of vaccination on the course of novel coronavirus infection in young patients
Authors: Kalamova Renata R. , Cherkashin Dmitry V. , Ulyatovsky Victor A. , Zarubenko Alexandra I. , Salakhbekov Islam S. , Filippov Vladimir Yu. , Bogdanov Dmitriy S. , Voevodin Evgeny E.
Published: January 2024

The features of the course of the new coronavirus infection in vaccinated and unvaccinated young patients (aged 18–35 years) were assessed. In total, 111 patients with new coronavirus infection were examined, and they were divided into two groups. The first group included 32 people vaccinated against the new coronavirus infection (21 men and 11 women; average age, 22. 31 ± 5. 04 years), and the second group included 79 unvaccinated people (70 men and 9 women; average age, 20. 76 ± 3. 674 years). A direct dependence of hospitalization time on the presence of vaccination was observed. The average volume of erythrocytes was significantly greater in the vaccinated group than in the unvaccinated group, and the average concentration of hemoglobin in erythrocytes was higher in the unvaccinated group, both at disease onset and over time. In addition, in the vaccinated group, the values of inflammatory markers in the blood such as erythrocyte sedimentation rate, C-reactive protein, ferritin, procalcitonin, and D-dimer, increase much faster. According to the results of repeated computed tomography, the unvaccinated group had longer persistence of signs of viral pneumonia. The primary pathology recorded on the electrocardiogram, particularly bradycardia, was more frequently recorded in the unvaccinated group. Overall, most patients, regardless of vaccination, had a mild course of new coronavirus infection. This may indicate a negative dependence of the severity of the new coronavirus infection on the age of the patient. Despite the low risk of developing complications of coronavirus infection at a young age, to prevent and quickly recover from a new coronavirus infection, all age groups are encouraged to receive vaccination, which will reduce the number of hospitalizations, burden on healthcare, and economic costs of medical care.
Professor Alexey Nikolaevich Kuchmin (on the 60th anniversary of his birth)
Authors: Nagorny Mikhail B. , Shulenin Sergey N. , Morozov Sergey  L.
Published: January 2024

On July 27, 2023, Alexey Nikolaevich Kuchmin, the Head of the Department of Propaedeutics of Internal Diseases of the Military Medical Academy, named after S. M. Kirov
doctor of Medical Sciences, Professor, and former chief therapist of the Ministry of Defense of the Russian Federation, turned 60 years old. A. N. Kuchmin was born on July 27, 1963, in Mineralnye Vody, Stavropol Territory. After graduation, he entered the Faculty of training doctors for the Navy of the Military Medical Academy named after S. M. Kirov, where he graduated with honors in 1986. For 4 years, he served as the Head of the medical center and the infirmary of the Baltic Fleet Naval Aviation. Since 1990, his life and fate have been inextricably linked with the Department of Propaedeutics of Internal Diseases of the Kirov Military Medical Academy, within the walls of which he has passed through a difficult but bright career path from a 3rd-year cadet to an associate Professor, from a teacher to a Professor and Head of the Department. Here, A. N. Kuchmin joined the scientific, pedagogical, and clinical ideas of Professor N. N. Savitsky. Having started his scientific activity under the guidance of Professor Yu. S. Malov, Alexey Nikolaevich devoted himself to the research of the most pressing issues of cardiology, pulmonology, and physiology. After graduating from the adjunct program in 1993 at the Department of Propaedeutics of Internal Diseases of the Academy, A. N. Kuchmin defended his PhD thesis on “The role of salivary glands in maintaining homeostasis in patients with hypertension”. Since that time, he has been a senior resident, then a teacher, associate Professor, and deputy Head of the Department of Propaedeutics of Internal Diseases (for clinical work) since 2005. In 2003, Alexey Nikolaevich defended his doctoral dissertation on cardiac arrhythmias in patients with bronchial asthma. His research interests now include issues in rapidly developing areas, such as endocrinology, ultrasound diagnostics, and functional diagnostics. During his work as the Chief therapist of the Ministry of Defense of the Russian Federation, A. N. Kuchmin proved himself to be a competent Head of the therapeutic service of the Ministry of Defense of the Russian Federation, particularly during the armed conflict in Abkhazia and Georgia. A. N. Kuchmin’s talent as a clinician and organizer of clinical and expert work was also manifested in his leadership from November 2008 to 2010 in the Department of Therapy of the State Institute of Advanced Training of Doctors of the Ministry of Defense of the Russian Federation and since 2015 in his native Department of Propaedeutics of Internal Diseases of the Military Medical Academy named after S. M. Kirov. In all his positions, Alexey Nikolaevich was and remains a highly professional specialist in his field with several clinical interests and knowledge.
Features of emergency medical care outside a medical organization in saint petersburg
Authors: Karailanov Mikhail G. , Panfilov Mikhail S. , Cherkasov Sergey N. , Prokin Igor G.
Published: January 2024

The organization of emergency medical care outside a medical organization in Saint Petersburg is analyzed. It has been established that a number of organizational issues related to the interaction between medical organizations and improving the efficiency of the ambulance service have not been fully resolved. Based on the analysis, the main directions of optimization of emergency medical services in this subject are proposed, taking into account a rational and effective approach to calculating the required number of emergency medical teams and their composition. It is shown that the strengthening of operational interaction between medical organizations and the creation of unified control centers for emergency medical teams will meet the needs of the population, create more comfortable conditions for emergency medical personnel. In general, the importance and necessity of this type of medical care is certainly high, and the ambulance service can be regarded as a factor of national security. The issued Order of the Ministry of Health of the Russian Federation No. 388n dated June 20, 2013 “On approval of the Procedure for the provision of emergency, including emergency specialized, medical care” regulated the activities of emergency, including emergency specialized, medical care throughout the territory of the Russian Federation as a separate particularly significant type of medical care and contributed to its further development and improvement. At the same time, there was an approach to calculating the required number of emergency medical teams, taking into account the rational use of available resources. All this testifies to the unified nature of the ambulance, including emergency specialized medical care. Only with the use of this model can maximum accessibility and, therefore, the effectiveness of emergency medical care be provided to patients in the largest districts of the cities of our country. Timely provision of residents of a large city with effective emergency medical care will reduce the statistics of mortality and disability. Providing medical care to the victim in the first minutes after the injury or the development of a life-threatening disease plays the most important role not only in increasing the chance of saving life, but also in a favorable outcome of the disease. To return an able — bodied citizen to the social environment is a task of the state level, since a working person is a guarantee of the security of the state in all senses of this expression.
Effect of topical application of a modified dosage form of granulocyte-colony stimulating factor in complex therapy of Ascherman syndrome
Authors: Ob’edkova Ksenia V. , Tovpeko Dmitry V. , Komarova Evgenia M. , Krikheli Inna O. , Ryzhov Julian R. , Gzgzyan Alexander M. , Tapilskaya Natalia I.
Published: January 2024

The effectiveness of the use of a modified intrauterine gel form of granulocyte colony stimulating factor in the complex treatment of Ascherman syndrome is evaluated. The study involved 31 patients with a history of Ascherman syndrome. For 6 months, the patients underwent weekly intrauterine administration of 1 ml of gel with a concentration of granulocyte colony stimulating factor of 9 million IU/ml using an intrauterine catheter. Monthly M-echo was evaluated on the 19th–22nd day of the menstrual cycle, as well as the volume of menstrual blood loss according to the Pictorial Blood Loss Assessment Chart. After the treatment was completed, a control hysteroscopy was performed. There is a statistically significant increase in M-echo from 2. 61 ± 1. 71 to 6. 52 ± 1. 23 mm (p 0. 001). At the same time, the proportion of patients with M-echo 6 and 7 mm increased from 6. 45 and 0% to 80. 65 and 51. 61, respectively, over the 6 months of the study. There is also a statistically significant increase in menstrual blood loss from 24. 9 ± 2. 6 to 53. 5 ± 3. 4 points on the Pictorial Blood Loss Assessment Chart (p 0. 001). A response to therapy was achieved in 17 patients, among them 12 patients were diagnosed with pregnancy that occurred spontaneously (17. 65%) or as a result of in vitro fertilization protocol (52. 9%). The data obtained indicate that intrauterine administration of a gel with granulocyte colony stimulating factor promotes endometrial regeneration in patients suffering from Ascherman syndrome, which is expressed in an increase in M-echo and the volume of menstrual blood loss. Thus, adjuvant use of a hydrogel with granulocyte colony stimulating factor and hyaluronic acid is an effective treatment option in restoring reproductive function and preventing recurrence of adhesiogenesis after surgical treatment of Ascherman syndrome. In general, the proposed gel form with granulocyte colony stimulating factor allows us to reduce the frequency of administration of the drug, which theoretically can increase both the compliance of patients primarily by reducing the number of invasive procedures, and reduce treatment costs.
Relationship of the myostatin level and secondary sarcopenia in patients undergoing programmed hemodialysis
Authors: Tsygan Vasily N. , Boriskina Olga L. , Yakovenko Aleksandr A. , Tutin Alexey P.
Published: January 2024

The role of myostatin in the development of sarcopenia in patients receiving programed hemodialysis and the severity of the relationship with other risk factors, particularly between the myostatin level in the blood and skeletal muscle indicators, were analyzed. A single-stage prospective non-interventional study was conducted among 196 patients (97 women and 99 men, aged 54–66 years) receiving programed hemodialysis. After signing the informed consent form, all patients underwent a series of examinations consisting of the assessment of anthropometric data, measurement of vital signs, determination of the state of the muscular system for the diagnosis of sarcopenia, including bioimpedance, and laboratory tests (clinical and biochemical blood tests). The level of myostatin in the blood serum of patients was determined once 10 min before the next hemodialysis session. A statistically significant negative correlation of myostatin level with age (ρ = –0. 361; p 0. 001), skeletal muscle strength (ρ = –0. 140; p = 0. 05), and walking speed (ρ = –0. 245; p 0. 001) was observed. High myostatin levels were more often detected in men (U = 2633, z = –5. 462; p 0. 001). A positive correlation between the levels of myostatin and interleukin-6 was found (ρ = 0. 410; p 0. 001). The use of myostatin for the diagnosis of sarcopenia had a sensitivity of 71. 4%, specificity of 71. 4%, cut-off point of 5. 01 ng/mL, and area under the curve of 0. 714 (95% confidence interval: 0. 632–0. 795; p 0. 001). An increase in myostatin levels above 5. 01 ng/mL increases the likelihood of sarcopenia by 6. 25 times (95% confidence interval: 3. 314–11. 788; χ2 = 34. 639; p 0. 001). The chances of an increase in myostatin above the threshold value by 2,196 times according to the results of a short international questionnaire for determining physical activity (95% confidence interval: 1. 209–3. 988; χ2 = 6. 78; p = 0. 009) were higher in patients with reduced physical activity than in patients with normal physical activity. In general, in patients with chronic kidney disease receiving programed hemodialysis, along with the determination of myostatin level, a positive statistically significant association of myostatin level with interleukin-6, male sex, age, and decreased physical activity was noted, and myostatin could be used as a predictor of sarcopenia.
ANALISIS KELAYAKAN FINANSIAL USAHA KERIPIK PISANG BLESSING (STUDI KASUS PADA USAHA KERIPIK BLESSING BANANA CHIPS DI DESA SIMPANG KANAN KECAMATAN SUMBERJO KABUPATEN TANGGAMUS)
Authors: Sari Widia Arum , Saty Fadila Marga , Desfaryani Rini , Fitri Annisa
Published: January 2024

Pisang merupakan salah satu komoditas hortikultura yang memiliki kandungan karbohidrat, nutrisi, mineral, dan kandungan serat yang sangat tinggi. Pisang dapat meningkatkan nilai tambah yaitu keripik pisang. Permasalahan umum bagi industri pengolahan keripik pisang Blessing ini adalah penurunan produski, kenaikan harga input, dan penurunan harga jual. Oleh karena itu maka dilakukan penelitian menghitung biaya dan penerimaan, menganalisis kelayakan finansial pada usaha, menganalisis sensitivitas pada usaha keripik pisang Blessing di Gunung Batu Kecamatan Sumberjo Kabupaten Tanggamus. Metode Pengumpulan data dilakukan dengan menggunakan data primer dan sekunder. Metode di lakukan dengan cara Purposive pada respondennya. Penelitian kuantitatif dilakukan untuk menganalisis kelayakan finansial yaitu NPV, IRR, Net B/C, dan Payback Period (PP) dan BEP. Berdasarkan hasil penelitian diperoleh usaha keripik pisang blessing memperoleh penerimaan sebesar Rp 1.781.313.333 dan Keuntungan sebesar Rp 574.232.500, analisis kelayakan finansial menunjukan bahwa usaha keripik pisang blessing ini layak untuk dijalankan, sensitivitas terhadap parameter kenaikan biaya variabel sebesar 5% usaha keripik pisang blessing masih layak untuk dijalankan dan hasil analisis sesitivitas terhadap penurunan penjualan sebesar 12% usaha keripik pisang masih dikatakan layak.
INOVASI MEDIA PEMBELAJARAN SEJARAH DI ERA REVOLUSI INDUSTRI 4.0 BERBASIS AR –VIDECK (AUGMENTED REALITY, VIDEO, KOMIK DIGITAL, PEARDECK, AND QUIZZIZ)
Authors: Nafi'ah Ulfatun , Djono Djono
Published: January 2024

Abstract: History learning is required to produce more innovation to answer the challenges and developments of the industrial revolution 4.0. This is because the students we are dealing with are the digital generation. Therefore, this research aims to produce innovative history learning media based on AR-VIDECK (augmented reality, video, digital comics, peardeck, and quizziz). This research uses the development method carried out by Davidson-Shiver and Rasmunssen. The model was selected based on suitability to appropriate development characteristics in developing AR-VIDECK media with stages 1) Analysis, 2) Evaluation Plan, 3) Simultaneous Design which includes design, system development, testing and Implementation and Formative evaluation. This phase can be done many times up to an indefinite time limit; 4) Full Implementation; 5) Summative Evaluation and Research. The data collection technique is in the form of a questionnaire. The type of data used is qualitative and quantitative data. The instrument used in this research was a questionnaire. The questionnaire created was measured using a scale. The data analysis technique uses qualitative descriptive analysis and quantitative descriptive analysis. Based on the results of product trials with 92.5% media experts and 95% material experts, the feasibility of AR-VIDECK learning media content is categorized as valid. Abstrak: Pembelajaran sejarah dituntut lebih banyak menghasilkan inovasi untuk menjawab tantangan dan perkembangan revolusi industri 4.0. Hal ini dikarenakan siswa yang dihadapi adalah generasi digital. Oleh karena itu, penelitian ini bertujuan untuk menghasilkan inovasi media pembelajaran sejarah berbasis AR-VIDECK (augmented reality, video, komik digital, peardeck, dan quizziz). Penelitian ini menggunakan metode pengembangan yang dilakukan oleh  Davidson-Shiver dan Rasmunssen. Model tersebut dipilih berdasarkan kesesuaian terhadap karakteristik pengembangan yang sesuai dalam mengembangan media AR-VIDECK dengan tahapan 1) Analisis, 2) Rencana Evaluasi, 3) Desain Serentak yang meliputi desain, pengembangan sistem, ujicoba dan implementasi dan evaluasi formatif. Fase ini dapat dilakukan berkali-kali hingga batas waktu yang tidak ditentukan; 4) Implementasi Penuh; 5) Evaluasi Sumatif dan Penelitian. Teknik pengumpulan data berbentuk angket. Jenis data yang digunakan data kualitatif dan kuantitatif. Instrumen yang digunakan dalam penelitian ini berupa angket. Angket yang dibuat diukur dengan menggunakan skala. Adapun teknik analisis data menggunakan analisis deskriptif kualitatif dan analisis deskriptif kuantitatif. Berdasarkan hasil uji coba produk kepada ahli media 92,5% dan ahli materi 95% maka kelayakan konten media pembelajaran AR-VIDECK dikategorikan valid.
MANAJEMEN PEMBELAJARAN BERDASARKAN SEJARAH KURIKULUM DI INDONESIA: SEBUAH SUDUT PANDANG TEORI BELAJAR
Authors: Hasan Hasan , Kuswandi Dedi , Thaariq Zahid Zufar At
Published: January 2024

Abstract: This study presents a theoretical framework for instructional management in Indonesia, taking into account the historical context of curriculum development and aligning it with the principles of sustainable development goals. Instructional management plays a crucial role in optimizing resources to achieve instructional objectives, and its significance is closely tied to the historical evolution of the curriculum in Indonesia. We examine the instructional management practices employed throughout the history of the curriculum in Indonesia, starting from the Rentjana Pelajaran in 1947 to the implementation of the Merdeka Curriculum since February 2022. By adopting a historical approach, we provide a narrative exploration of instructional management. This article uncovers insights into the theoretical shifts in learning approaches based on the established policies. Furthermore, the curriculum journey in Indonesia has been predominantly influenced by behavioristic learning theory. However, recent curriculum developments have embraced the principles of sustainable development goals. As a result, this article can serve as a valuable reference for teachers seeking guidance on effective instructional management in the classroom.Abstrak: Studi ini menyajikan kerangka teori untuk manajemen pembelajaran di Indonesia, dengan mempertimbangkan konteks historis pengembangan kurikulum dan menyelaraskannya dengan prinsip-prinsip tujuan pembangunan berkelanjutan. Manajemen pembelajaran memainkan peran penting dalam mengoptimalkan sumber daya untuk mencapai tujuan pembelajaran, dan signifikansinya terkait erat dengan evolusi historis kurikulum di Indonesia. Kami meneliti praktik manajemen pembelajaran yang digunakan sepanjang sejarah kurikulum di Indonesia, mulai dari Rentjana Pelajaran pada tahun 1947 hingga implementasi Kurikulum Merdeka sejak Februari 2022. Dengan mengadopsi pendekatan historis, kami memberikan eksplorasi naratif tentang manajemen pembelajaran. Artikel ini mengungkap wawasan tentang pergeseran teoritis dalam pendekatan pembelajaran berdasarkan kebijakan yang ditetapkan. Lebih jauh lagi, perjalanan kurikulum di Indonesia sebagian besar dipengaruhi oleh teori pembelajaran behavioristik. Namun, perkembangan kurikulum baru-baru ini telah merangkul prinsip-prinsip tujuan pembangunan berkelanjutan. Oleh karena itu, artikel ini dapat menjadi referensi yang berharga bagi para guru yang mencari panduan mengenai manajemen pembelajaran yang efektif di kelas.
Social capital and woman entrepreneurs: the characteristics of social capital among woman entrepreneurs across different life stages
Authors:   Alma Mater Europaea – ECM, Maribor, Slovenia, Vadnjal Mateja , Vadnjal Jaka ,   GEA College of Entrepreneurship, Ljubljana, Slovenia,   Swiss School of Business Management, Geneve, Switzerland, Vadnjal Brina ,   University of Primorska, Faculty of Mathematics, Natural Sciencies and Information technologies, Koper, Slovenia
Published: January 2024

This research examined women entrepreneurs’ social capital in their different life stages. The main hypothesis is that women would have different levels and forms of social capital as they move from one stage to another in their lives in a professional cycle. We observe emotional support and encouragement from the environment, and instrumental social capital, through which the entrepreneur accesses information, business partners, and other resources relevant to her entrepreneurial process. A survey was emailed to a sample of women’s businesses detected with the help of an algorithm in a business register. Finally, there were 340 fully answered questionnaires collected for the statistical analysis that utilized Levene’s F-test to confirm equality of variances, followed by Tukey’s post hoc test. Otherwise, Tamhane’s test does not assume equality of variances. Based on the study results, we could not confirm that motherhood, which includes parenting, being a wife, and being a housewife, has different impacts on women entrepreneurs in different life stages. We also cannot support the hypothesis that there is a difference in the importance of social networks. However, our research confirmed the difference in the importance of parental influence and the influence of friends and acquaintances on their entrepreneurial journey.
The role of logistics in economic growth and global competitiveness
Authors:   University of Kragujevac, Faculty of Economics, Republic of Serbia, Bugarčić Filip Ž. , Mićić Vladimir ,   University of Kragujevac, Faculty of Economics, Republic of Serbia, Stanišić Nenad ,   University of Kragujevac, Faculty of Economics, Republic of Serbia
Published: January 2024

There is a rising demand to find new patterns for economic growth and development, and improving competitiveness, where the role of logistics should be considered in more detail. The main purpose of the article is to examine and compare the effects of countries’ logistics performance in EU, BRICS, and ASEAN, and to test the role of individual logistics components. The research method is based on panel data using fixed effects regressions for the period 2007-2018. The results confirm the positive impact of logistics on economic growth and competitiveness in the total sample and EU countries, while logistics contributes to rising competitiveness in BRICS countries. Individual contributions of LPI components were also identified, presenting the importance of sub-indices for economic growth and national competitiveness. The research implications emphasize the role of logistics as a factor of economic growth and development and highlight its potential in rising national competitiveness. The main contribution is new evidence on the effects of logistics at the level of selected groups of countries, which highlights the importance of this sector and provides recommendations for economic policymakers.
YebC Modulates OspC and VlsE Inverse Regulation and VlsE Expression in Persistent Lyme Disease
Authors: Zoss Andrew , Raghunandanan Sajith , Yang X. Frank
Published: January 2024

Background & Hypothesis: Lyme disease, caused by the bacterium Borrelia burgdorferi, is the most common vector-borne infectious disease in the United States. Although easily treated with antibiotics, undiagnosed cases may develop into persistent infections with complications including Lyme carditis, neuroborreliosis, & arthritis. VlsE antigen variation is one of the major mechanisms employed by B. burgdorferi to establish persistent infection. We hypothesize that YebC modulates VlsE expression and antigen variation, enabling the shift from acute to persistent infection.
Materials & Methods: C3H/HeN or C3H/SCID mice were infected with the B. burgdorferi strain 5A4NP1, yebC mutant, and yebC complement at a dose of 105 or 106 spirochetes. Mice were sacrificed at days 7, 30, 60, and 90 post-infection and tissue samples were subjected to RNA and DNA extraction.
Results: YebC levels were closely associated with the upregulation of vlsE and the downregulation of ospC in vitro and in vivo. The yebC mutant displayed loss of infectivity in C3H/HeN mice, and reduced VlsE antigen variation.
Conclusion & Impact: This data demonstrates that YebC of B burgdorferi can regulate the frequency of vlsE recombination and modulates the inverse regulation of OspC and VlsE. This new factor may serve as an avenue for developing drugs which can target vlsE recombination to combat complications of persistent Lyme disease.
Effects of Diet, Gender, and Age on Liver Metabolism Upon Feeding a High Fat Diet
Authors: MacNeill Justin J. , Yadav Ajay K. , Krylov Alex , Morral Núria
Published: January 2024

Background/Objective: Currently, 30% of the USA population has non-alcoholic fatty liver disease (NAFLD), a condition that is increasing in parallel with the global obesity epidemic and life expectancy and is a risk factor for type 2 diabetes and cardiovascular disease. Aberrant transcriptional control of genes is a hallmark of metabolic disease. Thus, it is of interest to characterize how diet, age, and sex impacts various metabolic and signaling pathways upon progression to NAFLD.
Methods: A cohort of 7-week or 52-week-old male and female mice (n=8) were assigned a high-fat diet (HFD) or a low-fat diet (LFD) feeding regimen for 10 weeks, after which serum chemistries were obtained. Subsequently, gene expression in hepatic tissue samples was analyzed using RNA-seq and Western Blot.
Results: In both males and females, HDL, LDL, and total cholesterol were significantly increased with HFD in both age groups. In females, there was no significant difference in fasting blood glucose and insulin levels between any groups, while in males, both markers were significantly increased with HFD. RNA-seq data showed significant changes in gene expression correlating with diet, gender, and age. KEGG pathway analysis showed clustering of genes in fatty acid oxidation and synthesis pathways in mice fed a HFD, without affecting cholesterol synthesis enzymes. In aged mice, genes involved in extracellular matrix-receptor interaction were among the most affected. In males and females, young and aged, Western Blot analysis showed decreased expression of lipogenic enzymes ATP-citrate lyase and fatty acid synthase with HFD, but no changes of enzymes of cholesterol synthesis, confirming the RNA-seq data. No significant alterations were observed in insulin signaling.
Conclusion and Potential Impact: A HFD leads to a more severe phenotype in males than females, including increased fasting and non-fating glucose as well as insulin, and age exacerbates these abnormalities. Cholesterol is increased in both genders and is also exacerbated by age.
Detection of Bowel and Mesenteric Injuries Using Deep Learning Computer Vision Models
Authors: Mahajan Neal , Steenburg Scott D. , Gunderman Peter , Burns John , Iranmanesh Arya
Published: January 2024

Background/Objective:While only seen in 1-5% of patients who undergo a CT (computed tomography) scan, blunt bowel and mesenteric injuries (BMI) are associated with significantly increased morbidity and mortality. A significant cause of the increased morbidity of BMI is due to the difficulty of diagnosis from clinical and imaging information which leads to delay in diagnosis. Accurate and timely diagnosis is vital to reduce the morbidity of BMI.
Methods:For this project, our primary objective is to create a binary prediction model that determines if a patient has BMI based on their abdominal CT scans. Due to the importance of the early and definitive diagnosis of BMI in trauma patients, an extension of this project will seek to introduce explainability into the model to highlight which features on the CT scan caused the model to make its prediction. The patients with BMI were sourced from a trauma registry that recorded trauma cases from IU Health with relevant diagnosis codes. The images from our search will be reduced to the relevant slices for diagnosis of BMI and then used to train an ML model to makea yes/no prediction from the image. Once the model is trained, testing data will be evaluated on the model and the gradient vectors from the model during inference will be used to create a heatmap with GRAD-CAM that illustrates what portions of the image were relevant for the decision made by the algorithm.
Future Directions:Using the collected abdominal CTs, we can train our machine learning pipeline to detect BMI. Based on the performance of the model, we will determine if we need to collect more data. Then, we can evaluate the explainability of the model using GRAD-CAM and compareperformance of the ML model to the performance of expert and trainee radiologists.