bluuebunny/crossref_metadata_2025 huggingface dataset:
Состояние и тенденции развития спорта в Сахалинской области
Authors: Людвиг Л.П , Понизович А.А.
Published: September 2023

Индустрия спорта в современном сообществе выражается во всевозможных направленностях деятельности человека. С одной стороны, это существенная профессиональная деятельность для спортсменов, тренеров, менеджеров. С другой стороны, это отрасль предпринимательской деятельности и важный экономический ресурс, оказывающий существенное влияние на объем и динамику экономики. Статья посвящена оценке состояния и изучению проблем развития индустрии спорта в Сахалинской области.
Проблема совершенствования системы государственной и муниципальной собственности
Authors: Оскольченко А.В. , Саймаганбетов Н.К , Кузяшев А.Н
Published: September 2023

Социально-экономические преобразования в российской экономике актуализировали проблему эффективного использования государственной и муниципальной собственности как единого целого, определяющего экономическую основу государственного управления и местного самоуправления, которое в свою очередь определяет качество жизни-деятельности населения. Предприятия, учреждения и организации, находящиеся в собственности государства (муниципальных образований), как правило, относятся к сферам, которые имеют стратегическое значение в развитии отдельных регионов или в общегосударственном развитии. К таким сферам относятся средства телекоммуникации и связь, транспорт, экологическая защита, фундаментальная наука, социальная сфера, производственная сфера, производство продуктов, обеспечивающих энергетическую независимость.
«Роль государства в экономике: регулирование или свободный рынок?»
Authors: Походина М.А
Published: September 2023

Эта статья рассматривает дискуссию о роли государства в экономике, исследуя противоречия между концепциями регулирования и свободного рынка. Развивая тему и основываясь на примерах из различных стран, статья анализирует плюсы и минусы каждой модели и приходит к выводу о необходимости баланса между этими двумя подходами для достижения стабильной и устойчивой экономической системы.
Современные аспекты бизнес-планирования на предприятии (организации)
Authors: Романюта Т.Д
Published: September 2023

В статье раскрываются особенности бизнес-планирования на предприятии (организации). Определяется его роль в современном предпринимательстве. Выявлены классификация и основные разделы бизнес-планов на нынешнем этапе развития. В рамках статьи представлены основные понятия и методы оценки эффективности и рисков бизнеспланов.
Статистический анализ уровня жизни населения Воронежской области
Authors: Сердюк Е.А
Published: September 2023

В статье рассматриваются основные факторы, влияющие на уровень жизни, описываются показатели, используемые для измерения уровня жизни, также указывается на ограничения статистического анализа, связанные с неполными или неточными данными и подчеркивается его значение для понимания текущего состояния и разработки стратегий для улучшения уровня жизни населения.
Nigeria: The Effects of Identity Politics on Societal Security
Authors: AYDIN Hakan
Published: September 2023

Nigeria is prominent country of the African continent with its population, economy and energy resources. Political problems have shaped the security agenda of Nigeria, which was exposed to British colonialism, since the independence declared in 1960. The interruption of democratic processes with the emergence of military coups after the civil war environment and the declared republics between the years 1960-1999 is an indication that a societal security environment could not be established. The reason for this is the failure to ensure the integration of segments with different ethnic and religious characteristics. With the concept of identity being placed at the center of political discussions, terrorist activities of organizations with fundamentalist ideas are encountered. There is the Boko Haram terrorist organization in Nigeria, which has settled in an international context in connection with other organizations that have had an impact on the regional framework in the last 10 years. In this article, the terror problem of Nigeria is examined through historical, political, economic and societal dynamics. Although the identity politics approach that is constructed and formed is thought to be the main factor in the problem of terrorism, the importance of societal and economic development in overcoming this issue is emphasized when the interregional differences in Nigeria are taken into account.
Hiding complexes in fortified sites of the Bar Kokhba war
Authors: Raviv Dvir
Published: September 2023

Hiding complexes are among the well-attested archaeological remains of Roman-period Jewish settlement sites. Found chiefly in the Judean Lowlands and Lower Galilee, they consist of rock-cut subterranean facilities that are linked by an intricate network of narrow passageways and burrows, creating a sort of labyrinth beneath the settlement. In this article I propose a phenomenon that has not previously been addressed in the literature: namely, the association of hiding complexes with fortified settlements and forts from the time of the Bar Kokhba Revolt. The most conspicuous feature of these systems is that they permit movement underground from a fortified built-up area to the outskirts of the settlement or the open land beyond it. On the basis of an examination of the features, territorial extent and geographical distribution of the most prominent examples, and a comparison with the tunnels at Herodium, I propose that they were an important and planned defensive element of Bar Kokhba's military strategy.
Sacred and non-sacred: divine names in early rabbinic traditions
Authors: Sagiv Yonatan
Published: September 2023

Several early rabbinic sources list verses that contain potential divine names. These names are classified as sacred when they refer to the Jewish God, and as not sacred when they refer to other entities, such as false gods or angels. This article argues that the core of the list was based on ancient Second Temple traditions that were modified. These changes were motivated by developments within Jewish thought and the shifting of conceptions and beliefs. Some of these changes were the result of internal rabbinic developments and others were the sages' ambition to define the boundaries of Judaism, which sometimes carried a polemical response to Christian commentaries. This article proposes that analysis of these lists and the relationship between them can serve as an example for rabbinic attempts to reframe, rather than erase, their literary inheritance.
A hidden nusach: the linguistic literacy of the Maharam Lublin
Authors: Cohen Ohad , Nir Bracha
Published: September 2023

The study focuses on an individual rabbi from early-modern Poland, Maharam of Lublin, and on his proficiency as a writer. We explore the Maharam's competence in recruiting different linguistic devices to serve both specific textual functions and the overall communicative function of the text. Taking the combined perspectives of historical discourse analysis and usage-based corpus linguistics, we analyse one responsum as an example of this historically - and in our view linguistically - important source of study. Specifically, we investigate the distributions of the lexical items the Maharam employed in different textual units according to their linguistico-historical strata. Our analyses show that these distributions are either highly constrained or reflect a distributionally dominant component in each texteme, which corresponds to a particular discursive function. In writing this text, the Maharam skilfully and systematically transitions between different linguistic models. His command of the Hebrew strata reflects a literate, functionally motivated nusach.
Maskilic families in the Ottoman Empire
Authors: Karkason Tamir
Published: September 2023

This article analyses the character of Maskilic families in the Ottoman Empire in the nineteenth century. The Ottomans regarded the family as a cornerstone of society and a tool for maintaining social harmony and preventing disorder. Accordingly, an analysis of the Maskilic family forms an important component in prosopographical research into the circle of Maskilim. The Ottoman Maskilim came from the heart of the 'traditional' rabbinical elite, and like other Muslim and non-Muslim reformers and intellectuals they underwent and generated processes of modernization with a relatively limited measure of secularization. Maskilic families continued to be essentially patriarchal, both in Maskilic thought and in everyday reality. At the same time, however, the Haskalah permitted the introduction of more modern patterns, such as the expansion of women's agency and liberty. These processes occurred without challenging the structure of the family or the father's supremacy.
Determination of the exact daily gas intake according to the level of formation completion in the underground gas storage
Authors: Akhundova Nargiz R. , Aliyeva Ofeliya
Published: September 2023

This article derives the formula for the exact daily gas intake of a gas-dynamic incomplete flatbed gas injection well according to the level of formation completion in the underground gas storage (UGS). In natural gas fields and underground gas storages, the formation is incompletely saturated with hydrocarbons due to the level of completion of the formation. In the upper part of the formation there is a flat-radial simple leakage flow through the gas well, and in the unopened part there is a complex curved radial flow. Separate formulas have been developed for the exact daily volume consumption of hydrocarbon gas injected into these wells. For this purpose, gas dynamics problems for two different stationary gas flows have been solved. By adding up the daily volume of gas consumption according to these formulas, the formula of full daily consumption for replaced well No. 2 was obtained. Which is equal to the exact full daily volume consumption of flatbed well No. 1. Fluids and gases are known to enrich the water supply and field system. The boundaries of the latter are the contours of the pressure and the flow. The water pressure in the reservoir was determined by changing the sum of the volume of the cavity at the edge of the reservoir, the capacity of the created gas and the amount of injected gas.
On Implicative and Positive Implicative GE Algebras
Authors: Walendziak Andrzej
Published: September 2023

GE algebras (generalized exchange algebras), transitive GE algebras (tGE algebras, for short) and aGE algebras (that is, GE algebrasverifying the antisymmetry) are a generalization of Hilbert algebras. Here some properties and characterizations of these algebras are investigated. Connections between GE algebras and other classes of algebras of logic are studied. The implicative and positive implicative properties are discussed. It is shown that the class of positive implicative GE algebras (resp. the class of implicative aGE algebras) coincides with the class of generalized Tarski algebras (resp. the class of Tarski algebras). It is proved that for any aGE algebra the property of implicativity is equivalent to the commutative property. Moreover, several examples to illustrate the results are given. Finally, the interrelationships between some classes of implicative and positive implicative algebras are presented.
W obronie ortodoksji. Głosy antyheretyckie i antymuzułmańskie w Palei – historia, typologia, tekstologia
Authors: Skowronek Małgorzata
Published: September 2023

Artykuł poświęcony jest przeglądowi tekstów polemicznych, które w okresie kilkuset lat funkcjonowania zabytku literackiego znanego jako Paleja znalazły się w jego strukturze. Wypowiedzi przeciw nieortodoksyjnym, z punktu widzenia Kościoła prawosławnego, ruchom religijnym okazały się – jak świadczy materiał źródłowy pozyskany z wybranych cerkiewnosłowiańskich odpisów Palei – funkcjonować także w kodeksach o tematyce innej niż historyczna i prawna.  Niniejszy artykuł powstał w ramach projektu sfinansowanego ze środków Narodowego Centrum Nauki, przyznanych na podstawie decyzji nr DEC-2016/22/M/HS3/00212 (Herezje dualistyczne w dziejach Europy Południowo-Wschodniej IX–XV w.) oraz w ramach projektu sfinansowanego ze środków Narodowego Centrum Nauki, przyznanych na podstawie decyzji nr DEC- 2017/26/M/HS2/00335 (Literatura polemiczna Słowian prawosławnych w średniowieczu).
Wizerunek Mahometa w chrześcijańskiej wersji legendy o Sergiuszu Bahirze na przykładzie długiej redakcji arabskiej
Authors: Wolińska Teresa
Published: September 2023

Artykuł poświęcony jest wizerunkowi Mahometa w chrześcijańskiej wersji legendy o Sergiuszu Bahirze. Obraz ten daleki jest od obiektywizmu, ale pozwala zrozumieć, co wiedziano w Bizancjum i w Europie o islamie, i jak próbowano wytłumaczyć związki między nim a chrześcijaństwem. Dla chrześcijańskich autorów była to także okazja uczynienia założyciela islamu bliższym czytelnikom.  Niniejszy artykuł powstał w ramach projektu badawczego finansowanego przez Narodowe Centrum Nauki, decyzja nr DeC-2016/23/B/HS3/01891
Komunikacyjna analiza funkcji operatora ‘i to’ oraz jego implementacja na przykładzie “Pożegnania jesieni” Stanisława Ignacego Witkiewicza
Authors: Czechowski Wiesław
Published: September 2023

Artykuł zawiera rezultaty badania funkcji, jakie w komunikatach werbalnych pełni frazem ‘i to’. Do badania wykorzystano metodologię gramatyki komunikacyjnej. Pierwsza część pracy zawiera analizę systemową. Fraza ‘i to’ na poziomie organizacji treści pełni funkcję operatora dodawania. Zwraca uwagę zróżnicowanie funkcjonale dodawanych treści. Są nimi zarówno aktualizatory obrazów ideacyjnych, jak i wybrane argumenty oraz (meta)predykacje sekundarne. Zasadniczą rolą analizowanej frazy jest sygnalizowanie, że następująca po niej treść jest ważna, a nawet kluczowa dla prawidłowej i pełnej interpretacji treści komunikatu. Jej użycie służy gradacji emocji i pełni funkcję perswazyjną. W drugiej części artykułu znajduje się badanie sposobu wykorzystania operatora ‘i to’ w konstruowaniu treści tekstu literackiego na przykładzie powieści Stanisława Ignacego Witkiewicza “Pożegnanie jesieni”. Trzeba podkreślić, że używanie w prozie tego autora operatora ‘i to’ stanowi swego rodzaju powtarzalną technikę organizacji treści. Uwagę zwracają kreatywne substytucje argumentów i specyfikujących je predykatów sekundarnych oraz wymagające wysiłku interpretacyjnego metapredykacje. Komunikatom z frazą ‘i to’ towarzyszy nacechowanie wartościujące, co odzwierciedla przeżywane przez bohaterów powieści stany emocjonalne.
Język jako instrukcja obsługi
Authors: Tabakowska Elżbieta
Published: September 2023

Autorka postuluje rozpatrywanie języka w kategoriach instrukcji obsługi – w obu ogólnie przyjętych znaczeniach tego słowa: jako opis narzędzia i jako zbiór wskazówek dotyczących sposobu jego używania. Zakładając, że stworzony przez człowieka język jest narzędziem służącym do opisu świata, autor przyjmuje – za twórcami kognitywnej teorii języka – że leżący u podstaw języka proces przetwarzania informacji jest ucieleśniony, osadzony i zaangażowany, a zasadniczą właściwością języka jest metonimiczność. „Instrukcja obsługi języka” zakłada wiedzę tła, która umożliwia właściwe dopełnienie metonimii, konieczne dla zrozumienia wypowiedzi. Przyglądając się kryteriom rozróżnienia między literaturą i nie-literaturą w kontekście postulowanej „instrukcji”, autor przytacza szereg przykładów na poparcie tezy, że poznanie – także to, które dokonuje się poprzez język - jest wcielone, osadzone i zaangażowane, a więc odbywa się dzięki interakcji człowieka ze środowiskiem oraz w sferze ludzkich afektów i emocji. Nie może być obiektywne; różnica między „językiem potocznym” i „językiem poetyckim” jest ilościowa, a więc jest sprawą stopnia.
(Di)simulaciones discursivas en el habla coloquial andina
Authors: García-Dussán Éder
Published: September 2023

El propósito de este artículo es reflexionar sobre los orígenes sociohistóricos de las discriminaciones que gobiernan las interacciones en nuestra cultura. Para ello,se analiza el soporte que ha promocionado tanto las prácticas discursivas explícitas de la exclusión como las versiones más (di)simuladas y que, traspuestas en tratamiento cortés, también alejan al diferente. Esto se ejemplifica con dos casos frecuentes del habla coloquial andina. Los resultados permiten encontrar que la causa de este comportamiento se alimenta de las herencias que nos dejaron los fundadores y colonizadores judeoconversos, y se concluye que uno de sus legados a las sociedadesiberoamericanas es la perpetuación del complejo de Colón, emparentado con el síndrome de Caín. Al final, se propone como una salida a esta tendencia histórica la divulgación de tal herencia y sus efectos sociales.
El uso del stand up comedy en una interacción digital 360°. Caso: Mike’s comedy 360º
Authors:   , Nuñez Reyes Claudia del Pilar
Published: September 2023

Este estudio se enfoca en analizar el uso del stand up comedy como recurso publicitario de advertainment que se enmarca en un contenido de entretenimiento, y su presencia a través de una interacción digital 360°, que permite involucrar al consumidor en una publicidad digital con una experiencia inmersiva con la marca. Es un estudio cualitativo cuyo diseño es el estudio de caso, donde se presenta el anuncio publicitario “Mike’s comedy 360º” de la marca Mike´s, de bebida alcohólica en lata “ready to drink” (RTD). Se realizó entrevistas semiestructuradas a 10 mujeres y 10 hombres jóvenes de 20 a 25 años, consumidores de bebidas alcohólicas de Lima Oeste. Como resultado, el uso del stand up comedy contribuye a una mayor conexión, consideración y afinidad con la marca para un público joven; siendo pieza clave en la construcción de la percepción de la personalidad de marca. Esto sumado a la inmersividad de la interacción 360° que logra mayor atención y recordación del mensaje y la experiencia expuesta por la marca.
Influencia de la inclusión del café de especialidad en el desempeño exportador de la región Amazónica en el periodo del 2018 al 2021
Authors:   , Bautista Fernandez Christian Hilario
Published: September 2023

La presente tesis tiene como objetivo principal conocer como la inclusión del café de especialidad se vincula con el desempeño exportador de las empresas de la región Amazónica en el periodo 2018 al 2021. Para ello, las categorías estudiadas para el concepto “Café de Especialidad” son: “marca Cafés del Perú”, “Calidad Física y Sensorial” y “Variedad de Semillas”. Así mismo, para el concepto “Desempeño Exportador” las categorías estudiadas son: “Ventas Internacionales”, “Volumen Exportado” y “Participación de Mercados”. El desarrollo de esta investigación tiene un enfoque cualitativo y su diseño está basado en la teoría fundamentada, lo cual ha permitido profundizar en los conceptos planteados mediante el uso de entrevistas semiestructuradas las cuales se han realizado a empresas exportadoras de la región amazónica y otros especialistas relacionados al café de especialidad. La investigación realizada muestra que la inclusión del café de especialidad tiene un vínculo favorable en el desempeño exportador de las empresas exportadoras de la región Amazónica, puesto que la calidad física y sensorial, y las variedades de semillas ha originado nuevas oportunidades de negocios permitiendo a las empresas exportadoras obtener mejores ingresos, aumentar su rentabilidad e ingresar a nuevos mercados. Por otro lado, la marca cafés del Perú tiene una buena perspectiva como estrategias de promoción sin embargo pareciera no haber tenido influencia en el desempeño exportador de las empresas.
Relación entre cultura organizacional y satisfacción laboral en empresas del sector belleza, Lima Moderna 2022
Authors:   , Cachay Ramírez Yahaira Susety , Sullón Flores Mayra Esthefanny
Published: September 2023

El objetivo de este estudio fue investigar la relación entre la cultura organizacional y la satisfacción laboral en empresas del sector de la belleza en Lima moderna en el 2022. La cultura organizacional es nuestra primera variable y consta de cuatro dimensiones: involucramiento, consistencia, adaptación y misión. Se determinó como objetivos específicos la relación con cada una de las dimensiones mencionadas con la variable satisfacción laboral. Se aplicó una encuesta a 362 trabajadores de la industria de la belleza para lograr un objetivo principal. El método utilizado en el diseño del estudio fue no experimental transversal, no experimental debido a que no se manipularon las variables sobre una muestra determinada, ya que se desarrolló en el mismo año correspondiente al 2022. También se adoptó y utilizó un cuestionario de escala Likert que consta de 39 preguntas sobre variables de cultura organizacional y 20 preguntas sobre satisfacción laboral. Finalmente, la presente investigación tuvo como resultado que la cultura organizacional tiene una relación positiva media respecto a la satisfacción laboral. Esto se debe a que la muestra a la que se le aplico la encuesta determino una correlación Rs de 0.658, lo cual quiere decir que existe una relación directa entre las variables estudiadas. Esto significa que a mayor nivel de cultura organizacional mayor nivel de satisfacción laboral.
Campanhas Antitabagismo e a Nicotina
Authors: Wilson Santos Ed
Published: September 2023

O tabaco causa milhares de mortes todos os anos. A nicotina é a substância ativa do tabaco. Apesar de seus efeitos maléficos terem sido identificados e serem constantemente divulgados, inclusive pela igreja adventista por mais de 170 anos, ainda hoje milhares de pessoas ainda têm esse vício mortal. As mitocôndrias são organelas essenciais não apenas para a produção de energia, mas também para processos de apoptose, autofagia, sinalização redox, resposta imune e entrega de metabólitos. A homeostase mitocondrial depende de um equilíbrio na dinâmica mitocondrial (fusão e fissão). Estudos demonstraram que as funções mitocondriais e as alterações morfológicas dependem de um relógio circadiano viável. Mudanças neste relógio molecular alteram a função mitocondrial. O objetivo desse estudo é investigar os efeitos da exposição à nicotina no ciclo circadiano e na dinâmica mitocondrial, que podem levar a alterações metabólicas relevantes. Alterações na morfologia mitocondrial têm sido implicadas em vários processos fisiológicos e patológicos, como doenças neurodegenerativas e câncer.
Os Dinossauros na Literatura Adventista do Sétimo Dia: Um Breve Estudo
Authors: Vieira de Amorim Davi , Stencel Renato
Published: September 2023

Desde o século 19, o tema dos dinossauros tem aparecido de forma recorrente na literatura da Igreja Adventista do Sétimo Dia. Com as constantes descobertas de fósseis desses animais, muitos estudiosos adventistas buscam conciliar o relato bíblico da criação do mundo e a coexistência desses seres (uma vez que eles geralmente são usados nos meios científicos como evidência da teoria da evolução). O objetivo deste artigo é investigar a percepção adventista quanto ao assunto, desde os primórdios até o início do século 21, analisando o desenrolar das discussões e as influências envolvidas. Para a realização deste trabalho foi utilizado o método de análise bibliográfica. Dentre os principais autores pesquisados estão Ellen G. White, George M. Price, James L. Hayward, Samuel P. Tregelles e Francis H. Nichol. A pesquisa conclui que não há uma posição definida da igreja quanto ao tema, sendo que as duas explicações alternativas para a origem dos dinossauros – por criação divina ou por amalgamação – são claras e compreensíveis dentro de seus respectivos contextos hermenêuticos.
Sanayi Kuruluşlarının Mekânsal Değişim Üzerindeki Etkileri: Kozan Şehri Örneği
Authors: KÖSE Mustafa
Published: September 2023

Bu çalışma Kozan şehrinin mekânsal büyümesini ve şehrin çevresinde meydana gelen arazi kullanım değişimini incelemektedir. Şehir alanı artan nüfusun ihtiyacını karşılamak üzere etrafına doğru hızla yayılarak büyümüştür. Kozan merkezinin yaşadığı mekânsal değişim uydu görüntüleriyle saptanarak şehirsel büyümenin nedenleri belirlenmeye çalışılmıştır. Farklı yıllara ait uydu görüntüleri sınıflandırılarak arazi kullanım/örtüsü haritaları oluşturulmuştur. 1985-2022 yılları arasında şehrin yayılma alanında meydana gelen değişim arazi kullanım/örtüsü haritaları kullanılarak belirlenmiştir. İncelenen dönemde, Kozan şehri ve çevresinin arazi kullanımında büyük değişiklikler meydana gelmiştir. 1.800 hektarlık tarım arazisi konut ve konut dışı kentsel kullanıma dönüşmüştür. Sonuç olarak, hızlı kentleşme neticesinde arazi kullanımı/örtüsü önemli bir değişim ve dönüşüme uğramıştır. Şehirsel yayılmanın plansız bir şekilde devam etmesi, ilçe merkezinin etrafında yer alan tarım arazilerinin gelecekte daha da azalacağına işaret etmektedir.
Vers une cartographie régionale de l’état hydrique de la vigne basée sur des observations collaboratives
Authors: Pichon Léo , Brunel Guilhem , Zhang Yulin , Tisseyre Bruno
Published: September 2023

Le suivi de l’état hydrique de la vigne à l’échelle régionale est un enjeu majeur (Willwerth and Reynolds, 2020). Cependant, il existe peu d’outils disponibles à cette échelle (Rienth and Scholasch, 2019). La collecte collaborative d’observations est une alternative intéressante mais nécessite une quantité et une qualité de données collectées suffisantes (Rechenberger et al., 2015). Le projet ApeX-Vigne démontre que cette approche est pertinente pour cartographier l’état hydrique de la vigne à l’échelle régionale.
Regrafting and curettage of esca-affected vines: useful control techniques but difficult to implement
Authors: Dewasme Coralie , Mary Séverine , Roby Jean-Philippe
Published: September 2023

Grapevine trunk diseases affect 13 % of French vineyards and esca has become more prevalent in recent decades (Grosman & Doublet 2012). Fussler et al. (2008) reported that an average of 3.25 % of vines are affected by esca. Management of these vines, considered unproductive, often consists in cutting off the symptomatic arm or uprooting the vine. In this competitive environment, it is difficult for a newly planted vine to grow and return to production. Regeneration of diseased vines thus seems an interesting alternative approach to controlling esca.
An innovative interactive mapping tool to present research results: example of a terroir study in the context of climate change
Authors: David Laurence , De Rességuier Laure , Petitjean Théo , Tissot Cyril , Quénol Hervé , Le Roux Renan , Van Leeuwen Cornelis
Published: September 2023

Over the past decade, Story Map applications have been developed throughout the world under the impetus of software developers in the fields of visualization (Google Earth, Neatline, TripLine) and geographic information systems (ESRI, Knight Lab). These Story Map web applications allow information to be presented, shared and distributed in the form of interactive maps combined with images, text and audiovisual content. Using these tools to transfer the results of research projects is an innovative approach that can be highly effective, with their ease of access and user-friendly interface encouraging users to explore the data. Such a tool has been used to supplement scientific papers reporting the results of a research project on terroir and climate change in the Bordeaux region. The link to access it is https://www-iuem.univ-brest.fr/wapps/letg/adviclim/BDX/#.
Yeast derivatives: a promising alternative for white wine oxidation prevention
Authors: Nioi Claudia , Lisanti Maria Tiziana , Meunier Fabrice , Massot Arnaud , Moine Virginie
Published: September 2023

In the previous decade, the use of Yeast Derivatives (YD) was proposed as a new strategy to control wine oxidation (Comuzzo et al., 2015). These products are obtained from yeasts by autolytic or hydrolytic processes and then dried to obtain the commercial products. The aim of this work was to carry out a preliminary investigation of commercial YDs with different compositions in order to (i) compare their capacity to prevent white wine oxidation in comparison with conventional treatment using SO2, and (ii) evaluate their impact on wine quality.
Influence of cationic exchange for reducing pH on the composition and quality of sparkling wine
Authors: Just-Borràs Arnau , Pons-Mercadé Pere , Gombau Jordi , Giménez Pol , Vilomara Glòria , Conde Marta , Cantos Antoni , Canals Joan Miquel , Zamora Fernando
Published: September 2023

Climate change has without any doubt an important impact on viticulture and oenology. The composition of wine is being altered due to lack of rainfall and the increase in temperatures during the grape ripening period; it is therefore becoming more common to find wines with low titratable acidity, high ethanol content and high pH. The increase in pH is especially problematic in sparkling wines, because they need higher acidity to maintain adequate freshness. In this research, the effects of using cation exchange on sparkling wine composition and quality was studied.
Production of flavour compounds by wine yeasts is dependent on the management of their intracellular redox balance
Authors: Duncan James D. , Ortiz-Julien Anne , Setati Mathabatha E. , Divol Benoit
Published: September 2023

Wine yeasts produce ethanol and a myriad of other metabolites during fermentation that give the final wine its unique organoleptic fingerprint. The complex network of metabolic pathways leading to the production of these flavour compounds is largely dependent on redox enzymatic reactions that make use of the NAD(H) and NADP(H) cofactors. In this work, we investigated the redox cofactor balance and management of two genetically related yeast strains throughout alcoholic fermentation and monitored their production of key metabolites.
Plants: past and present in the battle against diabetes
Authors: Balewska Anita , Szczechla Magdalena
Published: September 2023

From ancient times, when medicine was based on folk knowledge, to the present era of advanced science, the beneficial effects of plants on various diseases, including diabetes, have been discovered. Approximately 537 million people worldwide have diabetes, and forecasts indicate further increases. Hence, there is a need to develop new effective therapies and interventions to support diabetes treatment. Many plants impact carbohydrate metabolism, and the amount of in vitro and in vivo research on animals and humans continues to grow, updating our knowledge about their potential applications in diabetes treatment and its complications. This review discusses six plant sources with proven anti-diabetic activity. The study serves as a literature review on plants and their derived compounds that exhibit hypoglycemic effects, which are significant in managing prediabetic conditions and diagnosed diabetes.
Orchestration of Corporate Social Responsibility in Company Law – Reframing Human Security through Education
Authors: Osuji Onyeka Kingsley , Edeji Obinna Christian
Published: September 2023

This paper aims to argue the fundamental significance of education in addressing notable gaps in the constitutive, performance, and evaluation criteria for corporate social responsibility (CSR) and endeavours to showcase the complementarity between education, human security, sustainable human development, and the pursuit of CSR as an ideal normative paradigm. An abstractive approach to studying CSR engages with corporate philanthropy, which has not been helpful outside traditional CSR paradigms without looking at key dynamics that can robustly underpin successful CSR. It relies on the systematic analysis of written data sources to theoretically explore the central significance, and complementarity between human security, education, and human dignity and how they can orchestrate a holistic CSR paradigm. In 1994, the UNDP in formulating the human security doctrine recognised the syncretic correlation between human security, education, and sustainable human development as fundamental elements that should underpin CSR. This paper contends that these are necessary intrinsic components of human dignity as the central factor that justifies a multi-dimensional and proactive approach to CSR.
Despite the criticisms against human security, this paper identifies it as an important concept that could instrumentally orchestrate a model of CSR that uniformly mainstreams sustainable human development and human dignity that leverages education which has routinely and traditionally been seen as a constitutive component of CSR. It reveals how a holistic path to CSR can reinvigorate the central pillars of human security and human dignity using education as a springboard and makes a compelling case for supporting explicit references to education in company law with appropriate human security informed constitutive, performance, and evaluation criteria which are absent in existing legally orchestrated CSR.
Labral Reconstruction via Capsular Augmentation Maintains Perfusion to the Acetabular Labrum and Locally Transferred Autograft
Authors: Cherian Nathan J. , Eberlin Christopher T. , Kucharik Michael P. , Abraham Paul F. , Nazal Mark R. , Dean Michael C. , Martin Scott D.
Published: September 2023

Background:

The purpose of the present study was to examine the effects of arthroscopic labral repair with capsular augmentation on blood flow in vivo with use of laser Doppler flowmetry (LDF) to measure microvascular perfusion of the labrum and autograft tissue.

Methods:

The present prospective case series included patients ≥18 years old who underwent arthroscopic acetabular labral repair with capsular augmentation; all procedures were performed by a single surgeon between 2018 and 2022. The LDF probe measured microvascular blood flow flux within 1 mm3 of the surrounding labral and capsular tissue of interest. Mean baseline measurements of flux were compared with readings immediately following capsular elevation and after completing labral augmentation. Blood flux changes were expressed as the percent change from the baseline measurements.

Results:

The present study included 41 patients (24 men [58.5%] and 17 women [41.5%]) with a mean age (and standard deviation) of 31.3 ± 8.4 years, a mean BMI of 24.6 ± 3.4 kg/m2, a mean lateral center-edge of angle 35.3° ± 4.9°, a mean Tönnis angle of 5.8° ± 5.8°, and a mean arterial pressure of 93.7 ± 10.9 mm Hg. Following capsular elevation, the mean percent change in capsular blood flow flux was significantly different from baseline (−9.24% [95% confidence interval (CI), −18.1% to −0.04%]; p < 0.001). Following labral augmentation, the mean percent change in labral blood flow flux was significantly different from baseline both medially (−22.3% [95% CI, −32.7% to −11.9%]; p < 0.001) and laterally (−32.5% [95% CI, −41.5% to −23.6%]; p = 0.041). There was no significant difference between the changes in medial and lateral perfusion following repair (p = 0.136).

Conclusions:

Labral repair with capsular augmentation sustains a reduced blood flow to the native labrum and capsular tissue at the time of fixation. The biological importance of this reduction is unknown, but these findings may serve as a benchmark for other labral preservation techniques and support future correlations with clinical outcomes.

Level of Evidence:

Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
BMC (Business Model Canvas) and SWOT Analysis Approach on the Development of Farmer Prosperity: A Study on Business Strategies of "Labu Madu" Enterprises
Authors: Imadura Rimbi , Qadarin Maryam , Hidayah Islamiati
Published: September 2023

This study is aimed to seek the role of micro Enterprises Labu Madu in Banyoksah, Sampang in prospering the farmer of pumpkin with BMC approach method and SWOT analysis. This study employed descriptive qualitative with SWOT analysis and BMC approach. The data was collected through observation, interview, and documentation. The result show that SWOT analysis with BMC approach found that the best strategy of Labu Madu enterprise to improve the welfare of pumpkin farmer is SO strategies which are first; products of Labu Madu need to displayed in the stores and use other social media as marketing such as: IG, and Shopee. Second, it is necessary to add variations to the menu of processed products from honey pumpkins, and customer requests to become resellers are a chance to increase sources of income. Third, it is necessary to take part in marketing training to increase level of producing of processed Labu Madu. Fourth, it is necessary to replace more sophisticated or modern technology so that the Labu Madu production process is easier and more efficient. Fifth, apart from having an outlet, it is necessary to open a branch to increase the source of income. To ensure the welfare of pumpkin farmer, Islamic empowerment principles needs to be applied. Moreover, sharecropping contracts also necessary to be conducted with strengthen the transparency and religiosity aspect which are ease to implement in religious culture of the farmer. Furthermore, building the café an establishing with mesmerizing view also would affect to income of the enterprise which in turn would increase the income of the farmer. In connection with that, hospitality, product diversification, and customer service should be considered for future development of the company.
Ultrasensitive monolithic dopamine microsensors employing vertically aligned carbon nanofibers.
Authors: Meng Lingju , Akhoundian Maedeh , Al-Azawi Anas , Shoja Yalda , Meinander Kristoffer , Suihkonen Sami , Franssila Sami
Published: September 2023

Brain-on-Chip devices, which enable on-chip cultures of neurons to simulate brain functions, are receiving tremendous attention from both fundamental and clinical research. Thus, microsensors are being developed to accomplish real-time monitoring of neurotransmitters, which are the benchmarks for neuron network operation. Electrochemical sensors are promising candidates for detecting a critical neurotransmitter, dopamine. However, current state-of-the-art electrochemical dopamine sensors are suffering from issues like limited sensitivity and cumbersome fabrication. Here, we report a novel route in monolithically microfabricating vertically aligned carbon nanofiber electrochemical dopamine microsensors with an anti-blistering slow cooling process. Thanks to the microfabrication process, we can achieve microsensors with complete insulation and large surface areas. The champion device shows extremely high sensitivity of 4.52×104 µA/µM·cm2 , which is two-orders-of-magnitude higher than current devices, and a highly competitive limit of detection of 0.243 nM. These figures-of-merit will open new windows for applications such as electrochemical recording from a single neuron.
Discrete Wavelet transform based Multiscale Deep CNN cascaded LSTM model for the classification of Brain Tumor
Authors: Annadurai Amrutha , Joseph Benoy , Prusty Manas Ranjan
Published: September 2023

A brain tumor denotes an anomalous mass or collection of cells that develops within the brain. We have considered about the three categories of brain tumors among the various 120 categories namely Glioma, Meningioma and Pituitary along with No Tumor. Automated classification of different brain tumor categories using Magnetic Resonance Imaging (MRI) brain scans is this paper's unique approach. In our proposed framework, we have introduced a cascade of multiscale deep Convolution Neural Network (CNN) and Long Short Term Memory (LSTM) Network to classify brain tumors using brain tumor MRI image dataset where the source images are first decomposed to extract modes from the MRI images using the Single-level Discrete 2D Wavelet Transform (dwt2) is applied. With the aim of our research, the segmentation of a single MRI image is partitioned into four modes: Contained within the available images are : a diagonal image, a vertical detail image, a horizontal detail image, and an approximation detail image. For the purpose of classifying brain tumours into Glioma, Meningioma, Pituitary, and No Tumour, the evaluated modes are fed into a multiscale deep convolution neural network (CNN) cascaded with an LSTM network. The 2000 image MRI dataset that is publically available is used to assess the proposed deep learning architecture. The outcomes demonstrate that the suggested method attained peak precision of 89.5% for Multi-Nomial classification and 98.5% for two-class classification when utilizing MRI images from the dataset. These accuracies were obtained utilising 5-Fold Cross-Validation (CV) for the Multi-Class scheme and the Hold-Out Validation method for the binary scheme.
Axion Topology in Photonic Crystal Domain Walls
Authors: Devescovi Chiara , Morales-Perez Antonio , Hwang Yoonseok , Garcia-Diez Mikel , Robredo Iñigo , Mañes Juan Luis , Bradlyn Barry , Garcia-Etxarri Aitzol , Vergniory Maia
Published: September 2023

Axion insulators are 3D magnetic higher-order topological insulators protected by inversion symmetry that exhibit hinge-localized chiral channels and induce quantized topological magnetoelectric effects. Recent research has suggested that axion insulators may be capable of detecting dark-matter axion-like particles by coupling to their axionic excitations. Beyond its fundamental theoretical interest, designing a photonic axion insulator offers the potential to enable the development of magnetically-tunable photonic switch devices through the manipulation of the axionic modes and their chiral propagation using external magnetic fields. Motivated by these facts, in this work, we propose a novel approach to induce axionic band topology in gyrotropic 3D Weyl photonic crystals gapped by supercell modulation. To quantize an axionic angle, we create domain walls across inversion-symmetric photonic crystals, incorporating a phase-obstruction in the supercell modulation of their dielectric elements. This allows us to bind chiral channels on inversion-related hinges, ultimately leading to the realization of an axionic chiral channel of light. Moreover, by controlling the gyrotropic response of the material, we demonstrate a physically accessible way of manipulating the axionic modes through a small external magnetic bias, which provides an effective topological switch between different 1D chiral photonic fiber configurations. Remarkably, the unidirectional axionic hinge states supported by the photonic axion insulator are buried in a fully connected 3D dielectric structure, thereby being protected from radiation through the electromagnetic continuum. As a result, they are highly suitable for applications in guided-light communication, where the preservation and non-reciprocal propagation of photonic signals are of paramount importance.
Turnover Intention and Continuing Professional Development of Rural Doctors from Targeted Admission Medical Education Program in China: A Cross-Sectional Study in the Post-COVID-19 Era
Authors: Wang Jingya , Chen Yijun , Zhang Hongmin , Zhang Jinghua
Published: September 2023

Background
China has officially implemented a special free medical education program known as the Targeted Admission Medical Education (TAME) program since 2010. Jiangxi Province, China, is a pioneer and representative of TAME programs. Since retaining TAME doctors remains a challenge, continuing professional development (CPD) is often seen as a viable retention strategy.
Methods
A snowball sampling method was adopted to collect survey responses from 1,369 TAME doctors with 5 to 10 years of work experience in Jiangxi Province, China. Multivariate binary logistic regression models were used to investigate the relationship between TAME doctors' turnover intention and demographic characteristics, work environment characteristics and CPD activities.
Results
Male doctors were less likely to report turnover intention (TI) than females (OR = 0.425, 95% CI: 0.315 to 0.573). Doctors who were the only child in their family had a higher likelihood of TI (OR = 1.892, 95% CI: 1.380 to 2.594), as did those who were married (OR = 2.228, 95% CI: 1.558 to 3.187). Rural doctors whose fathers were farmers were less likely to report TI (OR = 0.410, 95% CI: 0.249 to 0.676), and a similar effect was seen for mothers who worked on farms. The highest TI effects were identified among those had pursued continuing professional development in a degree program (OR = 6.927, 95% CI: 3.378 to 14.208) and had training in a higher-level institution totally for more than three months (OR = 2.848, 95% CI: 1.934 to 4.195).
Conclusion
The study found that rural doctors in China who are active in continuous professional development (CPD), particularly among those pursuing a degree program, have highest turnover intention. To effectively improve retention, it is crucial to consider a comprehensive approach that considers the unique challenges faced by rural doctors. To retain high-quality rural doctors developed through a specially designed free medical education program, it is necessary to provide competitive wages that match their professional skills, as reflected by their continuing professional development. The retention rate may be further improved by selecting students with strong rural connections and confirming their parents' engagement in farming. Additionally, work-life balance can be enhanced by considering their work location preferences, facilitating convenient fulfillment of family commitments.
Individualized Coexpression Network Strategies Employing Transcriptomic Data to Address Challenges in Stratification
Authors: Latapiat Verónica , Pedroso Inti , Saez Mauricio , Martin Alberto J. M.
Published: September 2023

The traditional network approach in gene expression analysis focuses on identifying relationships among gene expression patterns and associating them with metadata. In contrast, individualized coexpression networks offer a unique perspective by detecting underlying differences in gene expression datasets without known classifications, enabling sample stratification and providing insights into distinct phenotypes. This study aims to identify the strengths and limitations of two main approaches for generating individualized networks to study heterogeneous populations using easily accessible gene expression data. Two distinct families of methods were compared: the first method, based on statistical dependency and commonly used in single-cell genomics, successfully distinguished cell types in various datasets. The second approach, difference of correlation, has been applied to different cancer types and metabolic networks. We used two datasets with known classifications to experiment with scenarios where individualized networks apply. The evaluation involved neuronal cell types and breast cancer datasets. Our results revealed significant differences between the two approaches, suggesting dependencies on sample size, which determine the optimal method for specific applications. Through these evaluations, the dependency method demonstrated superior performance in capturing cell type variations and patient stratification compared to the difference correlation method. Nevertheless, both methods have limitations, including the need for multiple samples to assess correlations and potential challenges in handling heterogeneous sample groups. Individualized coexpression network methods offer valuable insights into biological systems, aiding in cell type classification, disease stratification, and personalized medicine applications. The results indicate their potential for precision medicine; however, researchers should consider their limitations and applicability to specific data types. Addressing sample diversity and size challenges will be pivotal in maximizing the benefits of individualized coexpression networks for future research and clinical applications.