bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of Subcritical Carbon Dioxide Extraction and Bran Stabilization Methods on Rice Bran Oil
Authors: Chia S. L. , Boo H. C. , Muhamad K. , Sulaiman R. , Umanan F. , Chong G. H.
Published: February 2015

The extraction of rice bran oil using the conventional organic solvent‐based Soxhlet method involves hazardous chemicals, whereas supercritical fluid extraction is a costly high‐temperature operating system. The subcritical carbon dioxide Soxhlet (SCDS) system, which operates at a low temperature, was evaluated for the extraction of rice bran oil in this study. In addition, rice bran that had been subjected to steam or hot‐air stabilization were compared with unstabilized rice bran (control). The yields; contents of tocopherols, tocotrienols and oryzanol; fatty acid profiles; and the oxidative stabilities of the extracted rice bran oils were analyzed. The yields using hexane and SCDS extraction were approximately 22 and 13–14.5 %, respectively. However, oil extracted using the SCDS system contained approximately 10 times more oryzanol and tocol compounds and had lower free fatty acid levels and peroxide values compared with hexane‐extracted oil. Overall, SCDS extraction of steamed rice bran represents a promising method to produce premium‐quality rice bran oil.
Brief report: Sex differences in suicide rates and suicide methods among adolescents in South Korea, Japan, Finland, and the US
Authors: Park Subin
Published: February 2015

Sex differences in suicide rates and suicide methods was compared among adolescents in South Korea, Japan, Finland, and the United States. This study analyzed suicide rates and suicide methods of adolescents aged 15–19 years in four countries, using the World Health Organization mortality database. Among both male and female adolescents, the most common method of suicide was jumping from heights in South Korea and hanging in Japan. In Finland, jumping in front of moving objects and firearms were frequently used by males, but not by females. In the United States, males were more likely to use firearms, and females were more likely to use poison. The male to female ratio of suicide rates was higher in the United States (3.8) and Finland (3.6) than in Korea (1.3) and Japan (1.9). Sex differences in suicide methods may contribute to differences in the suicide rates among males and female adolescents in different countries.
Body composition and behaviour in adult rats are influenced by maternal diet, maternal age and high-fat feeding
Authors: Ware S. , Voigt J.-P. , Langley-Evans S. C.
Published: February 2015

Fetal exposure to maternal undernutrition has lifelong consequences for physiological and metabolic function. Maternal low-protein diet is associated with an age-related phenotype in rats, characterised by a period of resistance to development of obesity in early adulthood, giving way to an obesity-prone, insulin-resistant state in later adulthood. Offspring of rats fed a control (18 % casein) or low-protein (9 % casein; LP) diet in pregnancy were challenged with a high-fat diet at 9 months of age. To assess whether other maternal factors modulated the programming effects of nutrition, offspring were studied from young (2–4 months old) and older (6–9 months old) mothers. Weight gain with a high-fat diet was attenuated in male offspring of older mothers fed LP (interaction of maternal age and diet; P = 0·011) and adipose tissue deposition was lower with LP feeding in both males and females (P < 0·05). Although the resistance to weight gain and adiposity was partially explained by lower energy intake in offspring of LP mothers (P < 0·001 males only), it was apparent that energy expenditure must be influenced by maternal diet and age. Assessment of locomotor activity indicated that energy expenditure associated with physical activity was unlikely to explain resistance to weight gain, but showed that offspring of older mothers were more anxious than those of younger mothers, with more rearing observed in a novel environment and on the elevated plus-maze. The data showed that in addition to maternal undernutrition, greater maternal age may influence development and long-term body composition in the rat.
Dietary patterns interact with APOA1/APOC3 polymorphisms to alter the risk of the metabolic syndrome: the Tehran Lipid and Glucose Study
Authors: Hosseini-Esfahani Firoozeh , Mirmiran Parvin , Daneshpour Maryam S. , Mehrabi Yadollah , Hedayati Mehdi , Soheilian-Khorzoghi Mona , Azizi Fereidoun
Published: February 2015

The interaction of genetic and dietary factors, as an area of CVD research, has been explored poorly. The aim of the present study was to examine the interaction of dietary patterns and three genetic variants of APOA1 and APOC3, both independently and in combination, relative to the risk of the metabolic syndrome (MetS) in Tehranian adults. In the present matched, nested case–control study, 414 subjects with the MetS and 414 controls were selected from the participants of the Tehran Lipid and Glucose Study. Dietary patterns were determined by factor analysis. APOC3 (rs5128 3238C>G) and APOA1 (rs670, − 75G>A and rs5069,+83C>T) SNP were genotyped by the conventional PCR followed by the restriction fragment length polymorphism technique. Overall, three major dietary patterns were extracted: healthy dietary pattern (HDP); Western dietary pattern (WDP); fat–sweet dietary pattern (FSDP). The A and T allele carriers of the APOA1 SNP had a greater risk of developing the MetS in the highest quartile of WDP scores (OR 3·22, 95 % CI 1·21, 8·58, Pinteraction= 0·03). Compared with other genotype combinations, the combined effect of APOC3/APOA1 (CC/GA+AA/CT+TT) genotypes showed a further increase in the risk of the MetS in the highest quartile of WDP scores (OR 1, 2·49, 8·73, 6·32, Ptrend< 0·001, Pinteraction= 0·003). A significant interaction was found between the quartiles of FSDP scores and the APOA1 diplotype (GA+AA/CT+TT). OR for these genotype carriers were 1, 0·65, 0·57 and 0·22 (Ptrend= 0·006) in the lowest to the highest quartile of FSDP scores when compared with the other combined genotypes (Pinteraction= 0·03). Our findings suggest that the WDP and FSDP are associated with APOA1 and APOC3 SNP in relation to the risk of the MetS.
Ignacio Ellacuría and the Salvadorean Revolution
Authors: GOULD JEFFREY L.
Published: February 2015

This article focuses on the political thought and practice of the martyred Jesuit intellectual during the late 1970s. It employs the concept of desencuentros, probing the relationship between linguistic misunderstandings and political division. The article highlights Ignacio Ellacuría's novel analyses of the relationship between the ecclesial and the popular organisations, led by the radical Left. It discusses his political thought in relationship to the author's research on the base communities of northern Morazán. The article also discusses the Jesuit scholar's critical support for the Junta Revolucionario de Gobierno (15 October 1979–2 January 1980). The concluding section discusses Ellacuría's relevance for contemporary Latin American politics.
Antiprioritarianism
Authors: GREAVES HILARY
Published: February 2015

Prioritarianism is supposed to be a theory of the overall good that captures the common intuition of ‘priority to the worse off’. But it is difficult to give precise content to the prioritarian claim. Over the past few decades, prioritarians have increasingly responded to this ‘content problem’ by formulating prioritarianism not in terms of an alleged primitive notion of quantity of well-being, but instead in terms of von Neumann–Morgenstern utility. The resulting two forms of prioritarianism (respectively, ‘Primitivist’ and ‘Technical’ prioritarianism) are not mere variants on a theme, but are entirely distinct theories, amenable to different motivating arguments and open to different objections. This article argues that the basic intuition of ‘priority to the worse off’ provides no support for Technical Prioritarianism: qua attempt to capture that intuition, the turn to von Neumann–Morgenstern utility is a retrograde step.
CPW-fed H-tree fractal antenna for WLAN, WIMAX, RFID, C-band, HiperLAN, and UWB applications
Authors: Reha Abdelati , El Amri Abdelkebir , Benhmammouch Othmane , Oulad Said Ahmed , El Ouadih Abdelhakim , Bouchouirbat Marouane
Published: February 2015

This paper presents three iterations of a coplanar waveguide-fed H-tree fractal antenna. Increasing the number of iterations allows us obtaining a multi-band and broad-band behavior. The proposed antennas are a good solution for wireless local area networks IEEE802.11 a/h/j/n/ac/y, worldwide interoperability for microwave access system IEEE802.16, radio frequency identification, C-band, high performance radio LAN, and ultra wideband applications. The simulations were performed in FEKO 6.3. The measurements were performed by the network analyzer HP 8719C.
The NLRP3 inflammasome is activated by nanoparticles through ATP, ADP and adenosine
Authors: Baron L , Gombault A , Fanny M , Villeret B , Savigny F , Guillou N , Panek C , Le Bert M , Lagente V , Rassendren F , Riteau N , Couillin I
Published: February 2015

The NLR pyrin domain containing 3 (NLRP3) inflammasome is a major component of the innate immune system, but its mechanism of activation by a wide range of molecules remains largely unknown. Widely used nano-sized inorganic metal oxides such as silica dioxide (nano-SiO2) and titanium dioxide (nano-TiO2) activate the NLRP3 inflammasome in macrophages similarly to silica or asbestos micro-sized particles. By investigating towards the molecular mechanisms of inflammasome activation in response to nanoparticles, we show here that active adenosine triphosphate (ATP) release and subsequent ATP, adenosine diphosphate (ADP) and adenosine receptor signalling are required for inflammasome activation. Nano-SiO2 or nano-TiO2 caused a significant increase in P2Y1, P2Y2, A2A and/or A2B receptor expression, whereas the P2X7 receptor was downregulated. Interestingly, IL-1β secretion in response to nanoparticles is increased by enhanced ATP and ADP hydrolysis, whereas it is decreased by adenosine degradation or selective A2A or A2B receptor inhibition. Downstream of these receptors, our results show that nanoparticles activate the NLRP3 inflammasome via activation of PLC-InsP3 and/or inhibition of adenylate cyclase (ADCY)-cAMP pathways. Finally, a high dose of adenosine triggers inflammasome activation and IL-1β secretion through adenosine cellular uptake by nucleotide transporters and by its subsequent transformation in ATP by adenosine kinase. In summary, we show for the first time that extracellular adenosine activates the NLRP3 inflammasome by two ways: by interacting with adenosine receptors at nanomolar/micromolar concentrations and through cellular uptake by equilibrative nucleoside transporters at millimolar concentrations. These findings provide new molecular insights on the mechanisms of NLRP3 inflammasome activation and new therapeutic strategies to control inflammation.
Genomic analysis of hybrid rice varieties reveals numerous superior alleles that contribute to heterosis
Authors: Huang Xuehui , Yang Shihua , Gong Junyi , Zhao Yan , Feng Qi , Gong Hao , Li Wenjun , Zhan Qilin , Cheng Benyi , Xia Junhui , Chen Neng , Hao Zhongna , Liu Kunyan , Zhu Chuanrang , Huang Tao , Zhao Qiang , Zhang Lei , Fan Danlin , Zhou Congcong , Lu Yiqi , Weng Qijun , Wang Zi-Xuan , Li Jiayang , Han Bin
Published: February 2015

Exploitation of heterosis is one of the most important applications of genetics in agriculture. However, the genetic mechanisms of heterosis are only partly understood, and a global view of heterosis from a representative number of hybrid combinations is lacking. Here we develop an integrated genomic approach to construct a genome map for 1,495 elite hybrid rice varieties and their inbred parental lines. We investigate 38 agronomic traits and identify 130 associated loci. In-depth analyses of the effects of heterozygous genotypes reveal that there are only a few loci with strong overdominance effects in hybrids, but a strong correlation is observed between the yield and the number of superior alleles. While most parental inbred lines have only a small number of superior alleles, high-yielding hybrid varieties have several. We conclude that the accumulation of numerous rare superior alleles with positive dominance is an important contributor to the heterotic phenomena.
Hydrogen sulfide modulates actin-dependent auxin transport via regulating ABPs results in changing of root development in Arabidopsis
Authors: Jia Honglei , Hu Yanfeng , Fan Tingting , Li Jisheng
Published: February 2015

Hydrogen sulfide (H2S) signaling has been considered a key regulator of plant developmental processes and defenses. In this study, we demonstrate that high levels of H2S inhibit auxin transport and lead to alterations in root system development. H2S inhibits auxin transport by altering the polar subcellular distribution of PIN proteins. The vesicle trafficking and distribution of the PIN proteins are an actin-dependent process. H2S changes the expression of several actin-binding proteins (ABPs) and decreases the occupancy percentage of F-actin bundles in the Arabidopsis roots. We observed the effects of H2S on F-actin in T-DNA insertion mutants of cpa, cpb and prf3, indicating that the effects of H2S on F-actin are partially removed in the mutant plants. Thus, these data imply that the ABPs act as downstream effectors of the H2S signal and thereby regulate the assembly and depolymerization of F-actin in root cells. Taken together, our data suggest that the existence of a tightly regulated intertwined signaling network between auxin, H2S and actin that controls root system development. In the proposed process, H2S plays an important role in modulating auxin transport by an actin-dependent method, which results in alterations in root development in Arabidopsis.
Zero Valent Iron Significantly Enhances Methane Production from Waste Activated Sludge by Improving Biochemical Methane Potential Rather Than Hydrolysis Rate
Authors: Liu Yiwen , Wang Qilin , Zhang Yaobin , Ni Bing-Jie
Published: February 2015

Anaerobic digestion has been widely applied for waste activated sludge (WAS) treatment. However, methane production from anaerobic digestion of WAS is usually limited by the slow hydrolysis rate and/or poor biochemical methane potential of WAS. This work systematically studied the effects of three different types of zero valent iron (i.e., iron powder, clean scrap and rusty scrap) on methane production from WAS in anaerobic digestion, by using both experimental and mathematical approaches. The results demonstrated that both the clean and the rusty iron scrap were more effective than the iron powder for improving methane production from WAS. Model-based analysis showed that ZVI addition significantly enhanced methane production from WAS through improving the biochemical methane potential of WAS rather than its hydrolysis rate. Economic analysis indicated that the ZVI-based technology for enhancing methane production from WAS is economically attractive, particularly considering that iron scrap can be freely acquired from industrial waste. Based on these results, the ZVI-based anaerobic digestion process of this work could be easily integrated with the conventional chemical phosphorus removal process in wastewater treatment plant to form a cost-effective and environment-friendly approach, enabling maximum resource recovery/reuse while achieving enhanced methane production in wastewater treatment system.
Loss of α1,6-fucosyltransferase suppressed liver regeneration: implication of core fucose in the regulation of growth factor receptor-mediated cellular signaling
Authors: Wang Yuqin , Fukuda Tomohiko , Isaji Tomoya , Lu Jishun , Gu Wei , Lee Ho-hsun , Ohkubo Yasuhito , Kamada Yoshihiro , Taniguchi Naoyuki , Miyoshi Eiji , Gu Jianguo
Published: February 2015

Core fucosylation is an important post-translational modification, which is catalyzed by α1,6-fucosyltransferase (Fut8). Increased expression of Fut8 has been shown in diverse carcinomas including hepatocarcinoma. In this study, we investigated the role of Fut8 expression in liver regeneration by using the 70% partial hepatectomy (PH) model and found that Fut8 is also critical for the regeneration of liver. Interestingly, we show that the Fut8 activities were significantly increased in the beginning of PH (~4d), but returned to the basal level in the late stage of PH. Lacking Fut8 led to delayed liver recovery in mice. This retardation mainly resulted from suppressed hepatocyte proliferation, as supported not only by a decreased phosphorylation level of epidermal growth factor (EGF) receptor and hepatocyte growth factor (HGF) receptor in the liver of Fut8−/− mice in vivo, but by the reduced response to exogenous EGF and HGF of the primary hepatocytes isolated from the Fut8−/− mice. Furthermore, an administration of L-fucose, which can increase GDP-fucose synthesis through a salvage pathway, significantly rescued the delayed liver regeneration of Fut8+/− mice. Overall, our study provides the first direct evidence for the involvement of Fut8 in liver regeneration.
A Au nanoparticle-incorporated sponge as a versatile transmission surface-enhanced Raman scattering substrate
Authors: Shin Kayeong , Chung Hoeil
Published: February 2015

We report a sponge-based transmission surface-enhanced Raman scattering (TSERS) substrate that combines the bulk sampling capabilities of a transmission measurement to improve the quantitative representation of sample concentration with several sponge properties useful for analysis such as fast sample uptake, easy sample enrichment, and a stable polymeric structure.
Sensing applications based on plasmonic nanopores: The hole story
Authors: Dahlin Andreas B.
Published: February 2015

A critical review of plasmonic nanopores for sensing applications is given with highlights from recent work.
Monodispersed nanoparticles of conjugated polyelectrolyte brush with high charge density for rapid, specific and label-free detection of tumor marker
Authors: Liu Xingfen , Shi Lin , Zhang Zhiyong , Fan Quli , Huang Yanqin , Su Shao , Fan Chunhai , Wang Lianhui , Huang Wei
Published: February 2015

Rapid and label-free detection of human α-fetoprotein (AFP) based on selective superquenching of monodispersed nanoparticles of conjugated polyelectrolyte.
Drug-free macromolecular therapeutics – a new paradigm in polymeric nanomedicines
Authors: Chu Te-Wei , Kopeček Jindřich
Published: February 2015

This review highlights an exciting new field of polymeric nanomedicine research – drug-free macromolecular therapeutics for cell apoptosis induction.
Discovery of a novel family of polycyclic aromatic molecules with unique reactivity and members valuable for fluorescent sensing and medicinal chemistry
Authors: Xiao Yi , Liu Fengyu , Chen Zhuo , Zhu Weipin , Xu Yufang , Qian Xuhong
Published: February 2015

We review major achievements in the study of derivatives of 1-oxo-1H-phenalene-2,3-dicarbonitrile.
The sequential continuous-flow hydrothermal synthesis of molybdenum disulphide
Authors: Dunne Peter W. , Munn Alexis S. , Starkey Chris L. , Lester Edward H.
Published: February 2015

MoS2 has been prepared by the sequential formation of thiomolybdates, conversion to MoS3 and decomposition to MoS2 in a continuous-flow hydrothermal process.
Thermodynamics of cellulose dissolution in an imidazolium acetate ionic liquid
Authors: Andanson J.-M. , Pádua A. A. H. , Costa Gomes M. F.
Published: February 2015

Microcrystalline cellulose dissolves exothermally in acetate-based ionic liquids hence its solubility is thermodynamically less favored at higher temperatures.
Synthesis of a mixed valence state Ce-MOF as an oxidase mimetic for the colorimetric detection of biothiols
Authors: Xiong Yuhao , Chen Siheng , Ye Fanggui , Su Lingjing , Zhang Cong , Shen Shufen , Zhao Shulin
Published: February 2015

An in situ partial oxidation synthetic strategy was used to fabricate a mixed valence state Ce-MOF with oxidase-like activity and a colorimetric approach was developed for the high-throughput detection of biothiols in serum samples.
A study on fluoride detection and assembly of hydroxyaromatic aldoximes caused by tetrabutylammonium fluoride
Authors: Tarai Arup , Baruah Jubaraj B.
Published: February 2015

Different assemblies formed by the interactions of tetrabutylammonium fluoride with hydroxy-aromatic oximes show characteristic optical properties.
Two polymorphs of 4-hydroxypiperidine with different NH configurations
Authors: Döring Cindy , Näther Christian , Jess Inke , Ibrom Kerstin , Jones Peter G.
Published: February 2015

4-Hydroxypiperidine 1 exists in two crystal forms, tetragonal 1t with axial NH and orthorhombic 1o with equatorial NH.
Virtual hydrate screening and coformer selection for improved relative humidity stability
Authors: Abramov Yuriy A.
Published: February 2015

The descriptors were determined, which can be most efficiently applied to virtual screening in order to provide answers to the following questions: 1) what is the propensity to form a solid state hydrate of a pharmaceutical compound, and 2) which coformer would provide for the highest stability with respect to relative humidity conditions?
Exploiting verdazyl radicals to assemble 2p–3d–4f one-dimensional chains
Authors: Wang Chao , Lin Shuang-Yan , Shi Wei , Cheng Peng , Tang Jinkui
Published: February 2015

Exploiting the coordination abilities of an isopropyl substituted verdazyl radical to transition metal and lanthanide(iii) ions represents an efficient approach to produce a system incorporating 2p, 3d and 4f spin carriers.
Iridium(iii) N-heterocyclic carbene complexes: an experimental and theoretical study of structural, spectroscopic, electrochemical and electrogenerated chemiluminescence properties
Authors: Barbante Gregory J. , Doeven Egan H. , Francis Paul S. , Stringer Bradley D. , Hogan Conor F. , Kheradmand Peyman R. , Wilson David J. D. , Barnard Peter J.
Published: February 2015

Theoretical and experimental studies of a series of iridium N-heterocyclic carbene complexes.
Copper(i) diselenocarbamate clusters: synthesis, structures and single-source precursors for Cu and Se composite materials
Authors: Dhayal Rajendra S. , Liao Jian-Hong , Hou Hsing-Nan , Ervilita Ria , Liao Ping-Kuei , Liu C. W.
Published: February 2015

The first Cu(i) compounds supported by dialkyl diselenocarbamates were reported to exhibit tetrahedral, hydride-centered tetracapped tetrahedral and hydride-centered tricapped tetrahedral core structures.
The concept of mixed organic ligands in metal–organic frameworks: design, tuning and functions
Authors: Yin Zheng , Zhou Yan-Ling , Zeng Ming-Hua , Kurmoo Mohamedally
Published: February 2015

The mixed organic ligand strategy is significant for the rational construction of MOFs, and furthermore for their functionality and tunability.
Effect of N-acetyl cysteine coated CdS:Mn/ZnS quantum dots on seed germination and seedling growth of snow pea (Pisum sativum L.): imaging and spectroscopic studies
Authors: Das Smruti , Wolfson Brandon P. , Tetard Laurene , Tharkur Jeremy , Bazata Joshua , Santra Swadeshmukul
Published: February 2015

Anthropogenic nanomaterials (ANMs), once produced, will inevitably be present in the environment.
The free-energy barrier to hydride transfer across a dipalladium complex
Authors: Vanston C. R. , Kearley G. J. , Edwards A. J. , Darwish T. A. , de Souza N. R. , Ramirez-Cuesta A. J. , Gardiner M. G.
Published: February 2015

We use density-functional theory molecular dynamics (DFT-MD) simulations to determine the hydride transfer coordinate between palladium centres of the crystallographically observed terminal hydride locations, Pd–Pd–H, originally postulated for the solution dynamics of the complex bis-NHC dipalladium hydride [{(MesIm)2CH2}2Pd2H][PF6], and then calculate the free-energy along this coordinate. We estimate the transfer barrier-height to be about 20 kcal mol−1 with a hydride transfer rate in the order of seconds at room temperature. We validate our DFT-MD modelling using inelastic neutron scattering which reveals anharmonicity of the hydride environment that is so pronounced that there is complete failure of the harmonic model for the hydride ligand. The simulations are extended to high temperature to bring the H-transfer to a rate that is accessible to the simulation technique.
Sustainable catalytic oxidation of alcohols over the interface between air and water
Authors: Huang Zhijun , Li Fengbo , Chen Bingfeng , Yuan Guoqing
Published: February 2015

Alcohols are oxidized to aldehydes or ketones in water over a hybrid nanocatalyst dispersed over the interface between air and water.
Toward white electroluminescence by ruthenium quinoxaline light emitting diodes
Authors: Shahroosvand Hashem , Rezaei Shiva , Mohajerani Ezeddin , Mahmoudi Malek
Published: February 2015

Exciplex transfer as a new approach to produce white electroluminescence in ruthenium quinoxaline light emitting diodes.
Preparation and evaluation of a layered double hydroxide film on a nanoporous anodic aluminum oxide/aluminum wire as a highly thermal-resistant solid-phase microextraction fiber
Authors: Abolghasemi Mir Mahdi , Yousefi Vahid , Amirshaghaghi Ahmad
Published: February 2015

A hierarchical layered double hydroxide framework on a nonporous anodic aluminum oxide/aluminum wire was used as a solid phase microextraction fiber for separation and determination of phenolic compounds.
Generation of graphene quantum dots by the oxidative cleavage of graphene oxide using the oxone oxidant
Authors: Shin Yonghun , Park Jintaek , Hyun Daesun , Yang Junghee , Lee Hyoyoung
Published: February 2015

Facile synthesis of graphene quantum dots using an acid-free oxone oxidant and graphene oxide was successfully developed by sono- and photo-oxidation reactions.
Temperature dependence of the radiative lifetimes in Ge and Si nanocrystals
Authors: Forero-Martinez Nancy C. , Thi Le Ha-Linh , Ning Ning , Vach Holger , Weissker Hans-Christian
Published: February 2015

The temperature dependence of fully hydrogenated Ge and Si nanocrystals is opposite: the lifetimes increase for Ge, while they decrease for Si. The effect is attenuated for reconstructed nanocrystals.
Manipulating directional cell motility using intracellular superparamagnetic nanoparticles
Authors: Bradshaw Michael , Clemons Tristan D. , Ho Diwei , Gutiérrez Lucía , Lázaro Francisco J. , House Michael J. , St. Pierre Timothy G. , Fear Mark W. , Wood Fiona M. , Iyer K. Swaminathan
Published: February 2015

Intracellular magnetic nanoparticles can be used to manipulate the direction of migrating keratinocytes and regulate the speed of migrating fibroblasts.
Mesoscale mechanics of twisting carbon nanotube yarns
Authors: Mirzaeifar Reza , Qin Zhao , Buehler Markus J.
Published: February 2015

Mesoscale mechanics of twisted CNT bundles.
Efficiency of [2 + 2] photodimerization of various stilbene derivatives within the DNA duplex scaffold
Authors: Doi Tetsuya , Kashida Hiromu , Asanuma Hiroyuki
Published: February 2015

[2 + 2] photodimerization of various stilbene derivatives successfully proceeded within the DNA duplex scaffold.
Synthesis, molecular modeling, and biological evaluation of quinazoline derivatives containing the 1,3,4-oxadiazole scaffold as novel inhibitors of VEGFR2
Authors: Qiao Fang , Yin Yong , Shen Yu-Ning , Wang She-Feng , Sha Shao , Wu Xun , Lu Ai-Min , Xu Chen , Zhang Wei-Ming , Zhu Hai-Liang
Published: February 2015

A series of 4-alkoxyquinazoline derivatives containing the 1,3,4-oxadiazole scaffold were designed and synthesized. Their inhibitory activities were tested against A549, MCF-7 and Hela. 4j showed the most potent inhibitory activity and may be a potential anticancer agent.
Understanding cancer and the anticancer activities of naphthoquinones – a review
Authors: Wellington Kevin W.
Published: February 2015

Naphthoquinone moieties are present in drugs such as doxorubicin which are used clinically to treat solid cancers.
Precursor directed regioselective synthesis of partially reduced benzo[e]indene through oxidative cyclization and benzo[h]quinolines
Authors: Singh Surjeet , Panwar Rahul , Yadav Pratik , Althagafi Ismail , Sahu Satya Narayan , Pratap Ramendra
Published: February 2015

Precursor directed synthesis of various benzo[h]quinolines and 4,5-dihydro-1H-benz[e]indene has been reported.
Facile synthesis and phase transition of V2O3 nanobelts
Authors: Xu Guanchen , Wang Xinsheng , Chen Xiao , Jiao Liying
Published: February 2015

The facile synthesis of V2O3 nanobelts from V2O5 nanobelts and the studies on its phase transition are reported.
I2–DMSO–PTSA: a simple and metal free oxidative cross coupling of imidazo[1,2-a]pyridines and methylketones
Authors: Chennapuram Madhu , Emmadi Narender Reddy , Bingi Chiranjeevi , Atmakur Krishnaiah
Published: February 2015

A simple, metal free and selective oxidative cross-coupling promoted by I2–DMSO in presence of PTSA has been developed with the use of imidazo[1,2-a]pyridines (1) and methyl ketones (2) to access 3 in a one pot reaction.
Temperature induced gelation transition of a fumed silica/PEG shear thickening fluid
Authors: Liu Xi-Qiang , Bao Rui-Ying , Wu Xiao-Jun , Yang Wei , Xie Bang-Hu , Yang Ming-Bo
Published: February 2015

An interesting gelation transition of fumed SiO2/PEG shear thickening fluid induced by elevating the temperature.
Fabrication of a novel ZnO/MMO/CNT nanohybrid derived from multi-cationic layered double hydroxide for photocatalytic degradation of azo dye under visible light
Authors: Khodam Fatemeh , Rezvani Zolfaghar , Amani-Ghadim Ali Reza
Published: February 2015

A facile and effective approach for assembling ZnO/MMO/CNT nanohybrid with excellent photodegradation performance under visible light is reported.
Magnetic microrods as a tool for microrheology
Authors: Brasovs Artis , Cīmurs Jānis , Ērglis Kaspars , Zeltins Andris , Berret Jean-Francois , Cēbers Andrejs
Published: February 2015

The protocol of microrheological measurements consists of recording the dynamics of the orientation of the rod when the magnetic field is applied at an angle to the rod and observing its relaxation after the field is switched off.
One-step synthesis of zinc–cobalt layered double hydroxide (Zn–Co-LDH) nanosheets for high-efficiency oxygen evolution reaction
Authors: Qiao Chen , Zhang Yuan , Zhu Youqi , Cao Chuanbao , Bao Xinhua , Xu Jiaqiang
Published: February 2015

Two-dimensional (2D) nanomaterials show great potential for electrocatalysis or other applications that require large surface area.
Ag/white graphene foam for catalytic oxidation of methanol with high efficiency and stability
Authors: Zhao Huijie , Song Jizhong , Song Xiufeng , Yan Zhong , Zeng Haibo
Published: February 2015

Oxidation of methanol not only eliminates contamination due to typical volatile organic compounds (VOCs), but also provides clean energy.
Solvothermal synthesis of hierarchical Eu2O3 nanostructures templated by PS-b-PMAA: morphology control via simple variation of water contents
Authors: Xiao Ying , Wang Xiaoyan , Wagner Thomas , Thiel Jürgen , Yao Yuan , Lin Yichao , Metwalli Ezzeldin , Liu Rui , Butt Hans Jürgen , Müller-Buschbaum Peter , Meng Jian-Qiang , Chen Liang , Sun Ling-Dong , Yan Chun-Hua , Cheng Ya-Jun
Published: February 2015

Morphology evolution of Eu2O3 nanostructures was achieved by simply varying the water content, templated by PS-b-PMAA under solvothermal treatment.
Ni/CdS/TiO2 nanotube array heterostructures for high performance photoelectrochemical biosensing
Authors: Huo Huanhuan , Xu Zhaodong , Zhang Ting , Xu Cailing
Published: February 2015

A novel photoelectrochemical (PEC) biosensing platform was constructed based on a ternary hybrid Ni/CdS/TiO2 nanotube array electrode, which was fabricated by the combination of electrochemical anodization and electrodeposition.
Enhanced uptake and siRNA-mediated knockdown of a biologically relevant gene using cyclodextrin polyrotaxane
Authors: Dandekar P. , Jain R. , Keil M. , Loretz B. , Koch M. , Wenz G. , Lehr C.-M.
Published: February 2015

Cellular investigations confirm the ability of cyclodextrin polyrotaxane nanoplexes to deliver siRNA for down-regulating genes relevant to the pathogenesis of tuberculosis.
Crystal structure and physical properties of Cr and Mn oxides with 3d3 electronic configuration and a K2NiF4-type structure
Authors: Kao Ting-Hui , Sakurai Hiroya , Kolodiazhnyi Taras , Suzuki Yutaro , Okabe Momoko , Asaka Toru , Fukuda Koichiro , Okubo Susumu , Ikeda Shohei , Hara Shigeo , Sakurai Takahiro , Ohta Hitoshi , Yang Hung-Duen
Published: February 2015

YSrCrO4 is first synthesized. The magnetic and dielectric properties of YCaCrO4, LaSrCrO4 and A2MnO4 (A = Sr and Ca) are investigated together with YSrCrO4.
A highly sensitive DNA sensor for attomolar detection of the BRCA1 gene: signal amplification with gold nanoparticle clusters
Authors: Rasheed P. Abdul , Sandhyarani N.
Published: February 2015

Gold nanoparticle clusters were successfully implemented signal amplification in an electrochemical DNA sensor.
A metal (Co)–organic framework-based chemiluminescence system for selective detection of l-cysteine
Authors: Yang Na , Song Hongjie , Wan Xiangyu , Fan Xiaoqing , Su Yingying , Lv Yi
Published: February 2015

A metal (Co)–Organic Framework–luminol chemiluminescence system was successfully established for the determination of l-cysteine.
Rh(iii)-catalyzed and alcohol-involved carbenoid C–H insertion into N-phenoxyacetamides using α-diazomalonates
Authors: Zhou Jie , Shi Jingjing , Liu Xuelei , Jia Jinlong , Song Huacan , Xu H. Eric , Yi Wei
Published: February 2015

Here a new, mild and efficient Rh(iii)-catalyzed and alcohol-involved carbenoid insertion (ortho-alkylation) intoN-phenoxyacetamides using α-diazomalonates has been developed.
FRET-capable supramolecular polymers based on a BODIPY-bridged pillar[5]arene dimer with BODIPY guests for mimicking the light-harvesting system of natural photosynthesis
Authors: Meng Lu-Bo , Li Dongqi , Xiong Shuhan , Hu Xiao-Yu , Wang Leyong , Li Guigen
Published: February 2015

FRET-capable supramolecular polymers based on a pillar[5]arene dimer and BODIPY derivatives were successfully constructed to mimic the photosynthetic light-harvesting system.
Te–Te and Te–C bond cleavage reactions using a monovalent gallanediyl
Authors: Ganesamoorthy Chelladurai , Bendt Georg , Bläser Dieter , Wölper Christoph , Schulz Stephan
Published: February 2015

Te–Te and Te–C bond cleavage occurs in reactions of monovalent LGa (L = [(2,6-i-Pr2-C6H3)NC(Me)]2CH) with Te, Ph2Te2and i-Pr2Te. (LGa-μ-Te)21, LGa(TePh)22and LGa(i-Pr)Tei-Pr3were characterized by heteronuclear NMR (1H,13C,125Te) and IR spectroscopy and by single crystal X-ray analyses.
A facile method to fabricate functionally integrated devices for oil/water separation
Authors: An Qi , Zhang Yihe , Lv Kaikai , Luan Xinglong , Zhang Qian , Shi Feng
Published: February 2015

In this paper, we present a facile method for the fabrication of a functionally integrated device, which has the multi-functions of the oil-containment boom, oil-sorption material, and water/oil-separating film, through a single immersion step in an ethanol solution of stearic acid.
Norbornene homopolymerization and copolymerization with ethylene by phosphine-sulfonate nickel catalysts
Authors: Chen Min , Zou Wenping , Cai Zhengguo , Chen Changle
Published: February 2015

Phosphine-sulfonate nickel catalyzed norbornene homopolymerization and copolymerization with ethylene with an interesting response to B(C6F5)3additive.
Preparation of ultrahigh-molecular-weight polyethylene grafted with polyvinyl alcohol hydrogel as an artificial joint
Authors: Chen Kai , Zhang Dekun , Cui Xiaotong , Wang Qingliang
Published: February 2015

A chemical grafting method was used to graft UHMWPE with PVA hydrogel to be used as an artificial joint.
The enantiopreference in the solid state probed in lamivudine crystal forms with mandelic acid
Authors: da Silva Cameron Capeletti , Martins Felipe Terra
Published: February 2015

Chiral recognition, even when there is not chiral resolution, observed in two crystal forms of lamivudine with mandelic acid.
A smart method for the fast and low-cost removal of biogenic amines from beverages by means of iron oxide nanoparticles
Authors: Bettini S. , Santino A. , Valli L. , Giancane G.
Published: February 2015

Silica capped iron oxide nanoparticles are used to bind biogenic amines dissolved in a wine sample. The adduct formed by the capped paramagnetic nanoparticles and amines is separated by a weak magnetic field without affecting the wine taste.
Correction: A hierarchical, stretchable and stiff fibrous biotemplate engineered using stagger-electrospinning for augmentation of rotator cuff tendon-healing
Authors: Zhao Song , Zhao Xin , Dong Shikui , Yu Jia , Pan Guoqing , Zhang Yang , Zhao Jinzhong , Cui Wenguo
Published: February 2015

Correction for ‘A hierarchical, stretchable and stiff fibrous biotemplate engineered using stagger-electrospinning for augmentation of rotator cuff tendon-healing’ by Song Zhao et al., J. Mater. Chem. B, 2015, 3, 990–1000.
Cyanostilbene bent-core molecules: a route to functional materials
Authors: Martínez-Abadía M. , Robles-Hernández B. , Villacampa B. , de la Fuente M. R. , Giménez R. , Ros M. B.
Published: February 2015

Multifunctional bent-core liquid crystals have been obtained by the incorporation of the high current interest cyanostilbene unit into a bent-shaped structure.
Molecular engineering of cycloisomaltooligosaccharide glucanotransferase from Bacillus circulans T-3040: structural determinants for the reaction product size and reactivity
Authors: Suzuki Ryuichiro , Suzuki Nobuhiro , Fujimoto Zui , Momma Mitsuru , Kimura Keitarou , Kitamura Shinichi , Kimura Atsuo , Funane Kazumi
Published: February 2015

Bacillus circulans T-3040 cycloisomaltooligosaccharide glucanotransferase (BcCITase) mainly produces cycloisomaltooctaose. By structure-based mutagenesis of a carbohydrate-binding module family 35 (BcCBM35) and catalytic domain, the product specificity was modified and catalytic activity was improved, which enabled us to obtain a greater yield of cycloisomaltodecaose.
Circulating PCSK9 levels are positively correlated with NMR-assessed atherogenic dyslipidaemia in patients with high cardiovascular risk
Authors: Guardiola Montse , Plana Núria , Ibarretxe Daiana , Cabré Anna , González Marta , Ribalta Josep , Masana Lluís
Published: February 2015

Circulating proprotein convertase subtilisin/kexin type 9 (PCSK9) positively correlates with the atherogenic dyslipidaemia characteristic of diabetic patients.
Primary Progressive Apraxia of Speech: Clinical Features and Acoustic and Neurologic Correlates
Authors: Duffy Joseph R. , Strand Edythe A. , Clark Heather , Machulda Mary , Whitwell Jennifer L. , Josephs Keith A.
Published: February 2015

Purpose

This study summarizes 2 illustrative cases of a neurodegenerative speech disorder, primary progressive apraxia of speech (AOS), as a vehicle for providing an overview of the disorder and an approach to describing and quantifying its perceptual features and some of its temporal acoustic attributes.

Method

Two individuals with primary progressive AOS underwent speech-language and neurologic evaluations on 2 occasions, ranging from 2.0 to 7.5 years postonset. Performance on several tests, tasks, and rating scales, as well as several acoustic measures, were compared over time within and between cases. Acoustic measures were compared with performance of control speakers.

Results

Both patients initially presented with AOS as the only or predominant sign of disease and without aphasia or dysarthria. The presenting features and temporal progression were captured in an AOS Rating Scale, an Articulation Error Score, and temporal acoustic measures of utterance duration, syllable rates per second, rates of speechlike alternating motion and sequential motion, and a pairwise variability index measure.

Conclusions

AOS can be the predominant manifestation of neurodegenerative disease. Clinical ratings of its attributes and acoustic measures of some of its temporal characteristics can support its diagnosis and help quantify its salient characteristics and progression over time.
Kinematic Measurements of the Vocal-Fold Displacement Waveform in Typical Children and Adult Populations: Quantification of High-Speed Endoscopic Videos
Authors: Patel Rita , Donohue Kevin D. , Unnikrishnan Harikrishnan , Kryscio Richard J.
Published: February 2015

Purpose

This article presents a quantitative method for assessing instantaneous and average lateral vocal-fold motion from high-speed digital imaging, with a focus on developmental changes in vocal-fold kinematics during childhood.

Method

Vocal-fold vibrations were analyzed for 28 children (aged 5–11 years) and 28 adults (aged 21–45 years) without voice disorders. The following kinematic features were analyzed from the vocal-fold displacement waveforms: relative velocity-based features (normalized average and peak opening and closing velocities), relative acceleration-based features (normalized peak opening and closing accelerations), speed quotient, and normalized peak displacement.

Results

Children exhibited significantly larger normalized peak displacements, normalized average and peak opening velocities, normalized average and peak closing velocities, peak opening and closing accelerations, and speed quotient compared to adult women. Values of normalized average closing velocity and speed quotient were higher in children compared to adult men.

Conclusions

When compared to adult men, developing children typically have higher estimates of kinematic features related to normalized displacement and its derivatives. In most cases, the kinematic features of children are closer to those of adult men than adult women. Even though boys experience greater changes in glottal length and pitch as they mature, results indicate that girls experience greater changes in kinematic features compared to boys.
Parental Intention to Support Video Game Play by Children With Autism Spectrum Disorder: An Application of the Theory of Planned Behavior
Authors: Finke Erinn H. , Hickerson Benjamin , McLaughlin Eileen
Published: February 2015

Purpose

The purpose of this study was to determine parental attitudes regarding engagement with video games by their children with autism spectrum disorder (ASD) and whether attitudes vary based on ASD symptom severity.

Method

Online survey methodology was used to gather information from parents of children with ASD between the ages of 8 and 12 years. The finalized data set included 152 cases. Descriptive statistics and frequency analyses were used to examine participant demographics and video game play. Descriptive and inferential statistics were used to evaluate questions on the theory of planned behavior. Regression analyses determined the predictive ability of the theory of planned behavior constructs, andttests provided additional descriptive information about between-group differences.

Results

Children with ASD play video games. There are no significant differences in the time, intensity, or types of games played based on severity of ASD symptoms (mild vs. moderate). Parents of children with ASD had positive attitudes about video game play.

Conclusions

Parents of children with ASD appear to support video game play. On average, parents indicated video game play was positive for their children with ASD, particularly if they believed the games were having a positive impact on their child's development.
Will Parents Participate in and Comply With Programs and Regimens Using Xylitol for Preventing Acute Otitis Media in Their Children?
Authors: Danhauer Jeffrey L. , Johnson Carole E. , Baker Jason A. , Ryu Jung A. , Smith Rachel A. , Umeda Claire J.
Published: February 2015

Purpose

Antiadhesive properties in xylitol, a natural sugar alcohol, can help prevent acute otitis media (AOM) in children by inhibiting harmful bacteria from colonizing and adhering to oral and nasopharyngeal areas and traveling to the Eustachian tube and middle ear. This study investigated parents' willingness to use and comply with a regimen of xylitol for preventing AOM in their preschool- and kindergarten-aged children.

Method

An Internet questionnaire was designed and administered to parents of young children in preschool and kindergarten settings.

Results

Most parents were unaware of xylitol's use for AOM and would not likely comply with regimens for preventing AOM in their children; however, parents having previous knowledge of xylitol and whose children had a history of AOM would be more likely to do so.

Conclusions

Generally, most of these parents did not know about xylitol and probably would not use it to prevent ear infections. Unfortunately, these results parallel earlier findings for teachers and schools, which present obstacles for establishing ear infection prevention programs using similar protocols for young children. The results showed that considerable education and age-appropriate vehicles for administering xylitol are needed before establishing AOM prevention programs in schools and/or at home.
Differential site attenuation without using free space antenna factor
Authors: Yun Jaehoon , Camell Dennis G. , Novotny David R. , Koepke Galen H. , Guerrieri Jeffrey R.
Published: February 2015

Differential site attenuation (DSA) to verify the performance of electromagnetic compatibility (EMC) facilities, open area test site and semi‐anechoic chamber, without using a calibrated free space antenna factor (AFFS) is proposed. In the evaluation of EMC facilities, the AFFS is one of the main uncertainty contributions. The measured results are reported and compared with the current site attenuations. It is shown that the proposed DSA has good discrimination capability in verifying the performance of EMC facilities.
84 Gbit/s SiGe BiCMOS duobinary serial data link including Serialiser/Deserialiser (SERDES) and 5‐tap FFE
Authors: De Keulenaer T. , Torfs G. , Ban Y. , Pierco R. , Vaernewyck R. , Vyncke A. , Li Z. , Sinsky J.H. , Kozicki B. , Yin X. , Bauwelinck J.
Published: February 2015

The increasing demand for bandwidth fuels the development towards high data rate electrical serial links. These links generally suffer from considerable frequency‐dependent loss, introducing the need for equalisation at 10 Gbit/s and higher. Modulation schemes with improved spectral efficiency, with respect to non‐retrun to zero (NRZ), combined with feed‐forward equalisation (FFE), allow increasing the chip‐to‐chip data rate with the drawback of a more complex, e.g. multi‐level, receiver (Rx). The use of duobinary modulation (DB) is presented to realise a high‐speed serial link. The increase in complexity of a DB Rx is limited, whereas the required channel bandwidth compared with NRZ is reduced. Furthermore, the need for equalisation when compared with PAM4 is reduced as the required roll‐off that is needed to create a duobinary modulated signal from an NRZ stream can incorporate the frequency‐dependent loss of the link.
34.3 fs pulse generation in an Er‐doped fibre laser at 201 MHz repetition rate
Authors: Li Xing , Zou Weiwen , Chen Jianping
Published: February 2015

A 34.3 fs pulse generation dechirped from a nonlinear polarization evolution (NPE)‐based modelocked Er‐doped fibre laser at a repetition rate of 201 MHz is reported. The output power is 38.5 mW at a pump power of 700 mW.
Over 20 MHz modulation bandwidth on 250 nm emission of AlGaN micro‐LEDs
Authors: Akhter M. , Pampili P. , Zubialevich V.Z. , Eason C. , Quan Z.H. , Maaskant P.P. , Parbrook P.J. , Corbett B.
Published: February 2015

Bandwidth measurements of deep ultra‐violet micro‐light‐emitting diode (LED) electroluminescence centred at 250 nm using a multiple quantum well aluminium gallium nitride (AlGaN)‐based LED structure grown on a sapphire substrate is presented. By controlled etching of the wafer surface, parabolically shaped micro‐LED structures were formed to enhance light emission through the substrate. Devices were tested on‐wafer and bandwidth measurements were carried out on individual emission peaks from the devices. A bandwidth of more than 20 MHz was achieved on the 250 nm peak.