bluuebunny/crossref_metadata_2025 huggingface dataset:
Nghiên cứu một số yếu tố liên quan đến hoạt độ enzyme Glucose-6phosphat Dehydrogenase trong sàng lọc sơ sinh bệnh thiếu hụt enzyme G6PD
Authors: Tạ Thị Lan Anh , Lê Minh Trác , Hoàng Thị Ngọc Lan , Đào Thị Thu Hiền , Lê Phạm Sỹ Cường , Nguyễn Thị Ngọc Ly , Trần Danh Cường , Đoàn Thị Kim Phượng
Published: October 2022

Đo hoạt độ enzyme Glucose-6-phosphat Dehydrogenase trong mẫu máu thấm khô được áp dụng trong sàng lọc thiếu hụt enzyme G6PD ở trẻ sơ sinh.

Mục tiêu: Phân tích mối liên quan giữa hoạt độ enzyme G6PD trong mẫu máu thấm khô với giới tính, tuổi lấy mẫu, cân nặng khi sinh và thuốc kháng sinh sử dụng ở trẻ sơ sinh.

Đối tượng và phương pháp nghiên cứu: Phương pháp mô tả cắt ngang hồi cứu. Thu thập số liệu về các biến số giới tính, tuổi lấy mẫu, cân nặng khi sinh, thuốc kháng sinh sử dụng và hoạt độ G6PD trong mẫu máu thấm khô trên 5886 trẻ sơ sinh. Nhóm nguy cơ thấp và nhóm nguy cơ cao được phân loại dựa trên ngưỡng hoạt độ G6PD lần lượt là ≤ l8 U/dL và > 18 U/dL.

Kết quả: Giá trị trung bình của hoạt độ enzyme Glucose-6-phosphat Dehydrogenase ở trẻ nam là 54,93 ± 15,999, ở trẻ nữ là 57,37 ± 15,767 U/dL. Nguy cơ cao thiếu hụt G6PD ở trẻ nam cao hơn đáng kể so với ở trẻ nữ. Nguy cơ cao ở nhóm có sử dụng kháng sinh cũng tăng có ý nghĩa thống kê so với trẻ không sử dụng kháng sinh với p < 0,01 . Đối với nhóm cân nặng < 2500 g có tỷ lệ trẻ thuộc nhóm nguy cơ cao gấp khoảng 2,5 lần so với nhóm trẻ có cân nặng ≥ 2500g. Giữa các nhóm tuổi lấy mẫu khác nhau và thời điểm lấy mẫu ở các mùa nóng và mùa lạnh không có sự khác biệt có ý nghĩa thống kê đến hoạt độ G6PD ở trẻ sơ sinh.

Kết luận: Hoạt độ G6PD ở mẫu giấy thấm máu gót chân của trẻ sơ sinh chịu ảnh hưởng của các yếu tố như giới tính, cân nặng lúc sinh và việc sử dụng thuốc kháng sinh nhưng không bị ảnh hưởng bởi tuổi lấy mẫu xét nghiệm và thời điểm lấy mẫu ở mùa nóng và mùa lạnh. Vì vậy, trong đánh giá nguy cơ thiếu enzyme G6PD cần chú ý phân tích đến các yếu tố ảnh hưởng đến hoạt độ enzym này.
Thái độ xử trí thai phụ nhiễm SARS-CoV-2 tại Bệnh viện Phụ sản Trung ương và Bệnh viện Nhiệt đới Trung ương năm 2021 - 2022
Authors: Trần Danh Cường , Đặng Công Việt , Nguyễn Thị Huyền Anh , Nguyễn Thị Bích Vân , Phạm Ngọc Thạch , Nguyễn Thành Lê
Published: October 2022

Đặt vấn đề: Dịch bệnh SARS-CoV-2 đã phát triển nhanh chóng và lan rộng ra khắp thế giới, lây nhiễm tới mọi đối tượng, mọi độ tuổi, bao gồm cả phụ nữ có thai. Chẩn đoán, xử trí và tiên lượng thai phụ nhiễm SARS-CoV-2 có ý nghĩa quan trọng. Mục tiêu: Nghiên cứu thái độ xử trí, điều trị và kết cục sản khoa của các thai phụ nhiễm SARS-CoV-2. Đối tượng: Thai phụ được chẩn đoán nhiễm SARS-CoV-2 tại Bệnh viện Phụ sản Trung ương và Bệnh viện Nhiệt đới Trung ương từ tháng 12/2021 đến tháng 2/2022.

Phương pháp: Mô tả tiến cứu.

Kết quả: Tuổi thai trung bình là 31,97 ± 6,98 tuần. 35% thai phụ có triệu chứng lâm sàng từ mức độ vừa trở lên. 35% số thai phụ cần được thở oxy, trong đó 33,33% cần thở máy. 21,67% cần điều trị tại ICU. Tỷ lệ tử vong là 1,67%. 56,67% bệnh nhân được sử dụng kháng sinh. 33,33% số thai phụ cần điều trị lovenox và 10% số thai phụ cần sử dụng thuốc kháng virus. 40% số thai phụ cần sử dụng corticosteroid. Trong số 28 trường hợp dừng thai tại viện, 60,71% cần mổ lấy thai vì lý do điều trị covid. 100% số trẻ sinh sinh ra đều xét nghiệm âm tính với SARS-CoV-2 dù đẻ thường hay mổ lấy thai.

Kết luận: Nghiên cứu đầu tiên tại Việt Nam về xử trí trên thai phụ nhiễm SARS-CoV-2. Xử trí sản khoa phụ thuộc vào cả vào tình trạng của bệnh và khả năng sống của thai. Đa số thai phụ nhiễm SARS-CoV-2 được mổ lấy thai vì tình trạng nặng của COVID-19. Tất cả trẻ sơ sinh đều âm tính với SARS-CoV-2.
Đặc điểm lâm sàng và kết quả điều trị chửa ngoài tử cung phối hợp chửa trong buồng tử cung tại Bệnh viện Phụ sản Trung ương
Authors: Đặng Thị Hồng Thiện , Đoàn Thị Thu Trang , Nguyễn Thị Hồng Phượng , Chu Thị Ngọc , Phạm Chi Mai , Nguyễn Đức Hà
Published: October 2022

Mục tiêu: Mô tả đặc điểm lâm sàng và kết quả điều trị các trường hợp chửa ngoài tử cung phối hợp với chửa trong buồng tử cung tại Bệnh viện Phụ sản Trung ương.

Đối tượng và phương pháp nghiên cứu: Nghiên cứu hồi cứu mô tả cắt ngang trên 55 trường hợp chửa ngoài tử cung phối hợp với chửa trong buồng tử cung được điều trị tại Bệnh viện Phụ Sản Trung ương từ tháng 01/2017 đến tháng 12/2021.

Kết quả nghiên cứu: 87,3% các bệnh nhân mang thai dựa vào các biện pháp hỗ trợ sinh sản, 1/5 số bệnh nhân có khối chửa ngoài tử cung vỡ tại thời điểm phẫu thuật, 83,6% các trường hợp được chẩn đoán tại thời điểm tuổi thai từ 5 - 8 tuần, hầu hết bệnh nhân có khối chửa ngoài nằm tại vòi tử cung, 82% các trường hợp có thai trong buồng tử cung phát triển bình thường sau điều trị.

Kết luận: Chửa ngoài tử cung kết hợp với chửa trong buồng tử cung ngày càng trở nên phổ biến hơn do sự phát triển của các biện pháp hỗ trợ sinh sản. Thai trong buồng tử cung phát triển bình thường sau phẫu thuật.
TINGKAT PARTISIPASI MASYARAKAT DALAM PEMELIHARAAN PENGHIJAUAN KOTA DI KECAMATAN SINJAI UTARA KABUPATEN SINJAI
Authors: Mappakalu Andi Mulawangsa , Nursaifullah
Published: October 2022

Tujuan penelitian untuk mengetahui bagaimana tingkat partisipasi masyarakat dalam memelihara pohon penghijauan kota di Kecamatan Sinjai Utara dan motif utama yang mempengaruhi masyarakat dalam pemeliharaan penghijauan kota di Kabupaten Sinjai. Metode penelitian yang digunakan adalah metode kualitatif dengan pendekatan deskriptif. Adapun teknik pengumpulan data melalui observasi, wawancara dan dokumentasi, sedangkan informan yang menjadi nara sumber adalah pegawai Dinas Lingkungan Hidup dan Kehutanan Kabupaten Sinjai, Lurah Lappa, Lurah Balangnipa, Lurah Biringere, Lurah Bongki dan masyarakat umum di Kecamatan Sinjai Utara.

Hasil penelitian terkait tingkat partisipasi masyarakat dalam pemeliharaan penghijauan kota di Kecamatan Sinjai Utara disimpulkan bahwa tingkat partisipasi masyarakat dalam memelihara pohon penghijauan yang sudah ada di pinggir jalan di Kecamatan Sinjai Utara sebagai ibu kota Sinjai sangat rendah. Dalam kurun waktu tahun 2007-2017 diperkirakan 50% pohon penghijauan dalam kota sudah hilang/rusak, akibat mati secara alamiah atau ditebang oleh masyarakat karena akar pohon yang besar dan  banyak merusak bangunan rumah warga, serta daunan yang berserakan dan merepotkan warga dalam membersihkan sampah dedaunan. Selain itu pula warga masyarakat khawatir kejatuhan pohon yang mudah tumbang bila terkena angin kencang, alasan lain adanya kabel listrik yang melintang diantara ranting pohon dan dikhawatirkan mengganggu arus listrik dan membahayakan pelanggan listrik.
Analisis Kebijakan Jakarta Smart City Menuju Masyarakat Madani
Authors: Jabbar Sangaji Muhammad Salman , Priyanti Noor Putri Zorayya , Navasari Suci
Published: October 2022

This paper aims to analyze and describe the development of the Jakarta Smart Cityter, including the advantages and disadvantages of the Jakarta Smart City which are associated with the use of information and communication technology to move towards civil society after more than four years. The method used in this research is literature review study. The results show that the implementation of Jakarta Smart City components such as smart mobility, smart government, smart economy, smart environment, smart living and smart people has been running well and is highly integrated with the use of information technology. From the research results, it can be concluded that the development of Jakarta Smart City which is now good, the relationship with the use of Information Technology is very close, while the disadvantage of Jakarta Smart City is that the development of information technology innovation is faster than the regulations, meaning that if there is the latest technological innovation it cannot be implemented immediately, must go through the budget regulation system. The structure of civil society in the city of Jakarta has been seen by the number of developments in large public areas and freedom from politics without any pressure. The government, the private sector and the public have collaborated in the development of a more innovative and transparent Jakarta.
Presidential Threshold: Harapan dan Tantangan Bacalon Presiden 2024
Authors: Sumardi Sumardi , Lutfi Muhammad , Nurdin Mochamat , Baharuddin Baharuddin
Published: October 2022

This paper aims to analyze how the government's level of satisfaction has so far been and how the inevitability of prospective leaders who will compete in the 2024 election celebrations for newcomers. The methodology used in this study uses a library research approach, starting with a search for articles using the keywords of government policies in the fields of economics, law, social and democratic and political dynamics ahead of the 2024 elections in the  Scopus and Google Scholar the 2015-2022 period and then reviewedbased on four stages, including: 1) Search for articles, 2) Mapping discussion topics, 3). Topic analysis, and 4). Further analysis with the support of credible data that has been published by credible survey institutions. The results of the study and analysis concluded that the hope of bringing in future leaders still reaps pessimism, this happens because in public reading of their satisfaction with the government's performance, in this case the Jokowi-Ma'ruf cabinet, which is already in its third year, is currently considered to have failed to control the government. policy on a number of aspects, especially regarding the fulfillment of public needs, and economic investment, then another challenge is political and democratic disruption, the existence of a presidential threshold will have an impact on the leadership relay which has an oligarchic background and network similar to the political strategy played by elites and political parties. so far. S
Pengaruh Tingkat Pendidikan Aparat Kecamatan Dengan Kinerja Pelayanan Pada Kantor Kecamatan Kajuara Kabupaten Bone
Authors: Adiputra Muhlis Hajar , Mukhlis Suardi
Published: October 2022

This paper aims to find out how the level of education of sub-district officials with service performance at the Kajuara District office, Bone Regency. The type of research used is quantitative research with a survey approach, which is research that takes a sample from one population and uses questionnaires as a data measurement tool. Data collection techniques through questionnaires (questionnaire) and documentation. This study used a sample of 100. The results of the study (1) The level of education of sub-district officials with service performance at the Kajuara District office, Bone Regency, influenced each other or had a good influence (2) Several factors influenced the education level of sub-district officials with service performance at the K ajuara District office. Bone is one of the factors of education up to high school and undergraduate.
DEUTSCHE WELLE TÜRKÇE’NİN YAYIN POLİTİKASININ SURİYELİ SIĞINMACILAR ÜZERİNDEN İNCELENMESİ
Authors: SAF Hacı Hasan
Published: October 2022

İletişim teknolojilerindeki gelişmeler, iletişim sektörünün büyümesini sağlamıştır. Böylece ülke sınırları içerisinde kalmış ulusal yayın politikaları, ülke sınırlarını aşarak uluslararası boyuta erişmiştir. Uluslararası haber kuruluşları kurulmuş ve bir sonraki adım olan küresel yayın kuruluşları ortaya çıkmıştır. Genelde tek dilde (İngilizce) yayın yapan bu kuruluşlar, daha sonraları faaliyet gösterdikleri ülkelerin dilinde yayın yapmışlardır. Bu yayın politikalarının nedenleri, amaçları ve sonuçları ise sürekli bir tartışma konusu olmuştur. Uluslararası haber ve yayın kuruluşlarına yönelik tartışmalar, bu konulara yönelik yaklaşım ve teorileri beraberinde getirmiştir. Kültür ve medya emperyalizmi, çok uluslu şirketler ve propaganda kavramları; bu tartışmalara yönelik geliştirilen kavramlardandır. Bu kavramlar, genel olarak uluslararası eşitsiz iletişim akışının gelişmiş ülkelerin gelişmemiş ya da gelişmekte olan ülkeler üzerindeki etkisini artırdığını ortaya koymaktadır. Uluslararası haber kuruluşları da bu sürece katkı sağlamakta ve bağlı oldukları ülkelerin politikalarına paralel yayın politikası uygulamaktadır. Türkiye’de de birçok Türkçe yayın yapan haber kuruluşu bulunmaktadır. Bu uluslararası haber kuruluşlarının incelenmesi ise elzemdir. Çalışmada Türkçe yayın yapan haber kuruluşlarının yayın politikalarının Alman Dışişleri Bakanlığına bağlı Deutsche Welle (Almanya’nın Sesi) Türkçe üzerinden incelenmesi amaçlanmıştır. Son yıllarda artan sığınmacı akınları Türkiye’yi de etkilemiştir. Son 10 yıldır artan Suriyeli sığınmacı sayısına Afganistan ve Pakistan’dan gelen sığınmacılar da eklenmiştir. Siyasetçiler ve yurttaşlar tarafından sıklıkla eleştirilen ve tepki gösterilen sığınmacılar ve onlara yönelik politikalar, son dönemlerde daha da şiddetli tepkilere maruz kalmıştır. 2022 yılının Mayıs ayında çevrede bulunan kadın ve çocukların görüntülerini gizli ve açıktan kayıt altına alan Suriyeli, Afgan ve Pakistanlı sığınmacılar, bu görüntüleri sosyal medyada tepki çeken metinlerle paylaşmışlardır. Bu paylaşımlar ise sosyal medyada hızla yayılmış, Türkiye Cumhuriyeti yurttaşları tarafından tepkiyle karşılanmışlardır. Böylesi bir durumda, sığınmacıların Avrupa’ya geçişini istemeyen ve Türkiye’de barınmalarını isteyen Almanya’ya bağlı bir yayın kuruluşu olan DW Türkçe’nin yayın politikası ise tartışılmaya değerdir. Çalışmada sığınmacılara yönelik tepkilerin arttığı 2022 yılı Mayıs ayında DW Türkçe’nin yayınladığı altı haber eleştirel söylem analizi ile çözümlenmiştir. Çözümleme sonucunda DW Türkçe’nin Almanya’nın sığınmacı politikasına paralel bir yayın politikası geliştirdiği görülmüştür.
Efficiency of mapping epistatic quantitative trait loci
Authors:   , Souza Camila Angélica Santos
Published: October 2022

Previous methodological investigations on epistatic QTL mapping have shown that this procedure is powerful, efficient to control the false positive rate (FPR), and precise to localize QTLs. The objective of this simulation-based study is to show that mapping epistatic QTLs is not almost perfect. The standard procedures for the most important software available maximized the power of detection for QTLs (56-74% on average), associated with a very high FPR (65%) and a low power for the epistatic pairs (7%). Increasing the average power for epistatic pairs (14%) highly increased the related FPR. Adopting a procedure to find the best balance between power and FPR, there was a significant decrease in the power of QTL detection (17-31% on average), associated with a low average power for epistatic pairs (8%) and an average FPR of 31% for QTLs and 16% for epistatic pairs. We believe that the main reasons for these negative results are simplified modelling of the epistatic effects and no inclusion of minor genes (2/3 of the FPR for QTLs were due to minor genes). Keywords: Epistasis. QTL detection power. False positive rate. Mapping precision.
Identificação de análogos a genes de resistência (RGAs) a Hemileia vastatrix no genoma Coffea arabica e avaliação da expressão gênica na interação
Authors:   , Estanislau Giovana Gomes
Published: October 2022

Das mais de 100 espécies de café, Coffea arabica e Coffea canephora são as de maior interesse comercial. As pragas e doenças que incidem sobre os cafeeiros são responsáveis pela redução da qualidade e produtividade da cultura, além de elevarem os custos de produção e os riscos ambientais advindos da aplicação de agrotóxicos. Um exemplo é a doença causada pelo fungo Hemileia vastatrix. Alternativas de controle das doenças do cafeeiro têm sido desenvolvidas, com destaque à obtenção e uso de cultivares resistentes. Sendo assim, os estudos do genoma e genética funcional de plantas e interações com patógenos aumentaram consideravelmente a compreensão acerca das bases moleculares associadas com o processo de infecção e defesa das plantas. Essas tecnologias têm fornecido oportunidade para selecionar novos alvos a serem incorporados nas novas cultivares com o objetivo de obter resistência duradoura. Um alvo candidato importante a ser explorado são os genes PRRs (Pattern Recognition Receptor) e R (Plant resistance genes), chamados de análogos de genes de resistência (Resistance Gene Analog -RGAs) que compartilham domínios e motivos conservados. Sendo assim, o objetivo desse estudo foi identificar e classificar análogos a genes de resistência (RGAs) no genoma de C. arabica e analisar sua expressão em transcriptoma da interação Coffea-Hemileia vastatrix. Para isso, uma abordagem baseada em predição de domínios funcionais em proteínas codificadas pelos RGAs foi empregada, fazendo uso de duas ferramentas, sendo elas, o RRGPredictor e o DRAGO2.Foram identificadas dezenove classes gênicas e vinte e cinco genes candidatos com potencial envolvidos na resistência de C. arabica a H.vastatrix. No transcriptoma da interação Coffea-H. vastatrix foi observada uma possível atuação dos genes identificados na resistência pré-haustorial do cafeeiro. A identificação desses genes permitirá entender melhor como funciona a interação entre Coffea e Hemileia vastatrix, além de contribuírem para a seleção assistida de cultivares cafeeiras resistentes nos programas de melhoramento. Palavras-chave: Bioinformática. Ferrugem no cafeeiro. Análogos de genes a resistência.
A systematic review on efficacy of Virechan karma on Psoriasis w.s.r to Ek-kustha
Authors: Verma Vandana , Singh Shefali , Abhinav
Published: October 2022

Background of the study: The reported prevalence of Psoriasis in countries ranges between 0.09% and 11.43%, making Psoriasis a serious global problem with at least 100 million individuals affected worldwide. It is far more than ‘just a skin disease’ it has an unpredictable course of symptoms, a number of external triggers and significant comorbidities, including arthritis, cardiovascular diseases, metabolic syndrome, inflammatory bowel disease and depression. Inspite of having recent development in modern medicine there is no specific medication for cure of Psoriasis it can be treated but not cured. Panchkarma(pentad therapy) and Shaman Chikitsa(pacification therapy) in Ayurveda may fill the gaps that exist regarding treatment. This systematic review analyses the role of Virechan karma(medicated purgation therapy) in the management of Psoriasis based on outcome of published research.

Objective: Effectiveness of Virechan karma in management of Psoriasis.

Method: Published research data were obtained from different E- databases eg. Pubmed central, Google scholar, Research gate, Scopus, Web of science, hand search. The inclusion criteria of the selection of papers includes the studies conducted on the symptoms of Ek kustha, PASI scoring, standard protocol followed for Virechan Karma and the papers were excluded from the study which included only Nitya Virechan karma, only Shnehan karma(oleation therapy), other Panchkarma(pentad therapy) modality like Basti(medicated Enema) etc.

Result and Conclusion: The maximum incidence of Psoriasis disease was found in subjects belonging to 30-40 year age group having Vata-Pitta dominant Sharirik Prakriti(somatic constituent) and Rajsika Mansika Prakriti(Psychic constituent).Virechan karma with Shaman Chikitsa showed significant improvement in Psoriasis patients than Vaman karma(medicted emesis)&Virechankarma.
Tamra Bhasma preparation by two methods and evaluating their effect on the Liver Function test pre-clinically
Authors: Ophale Shivhar , Gupta Shashiprabha L , Dubewar Arati
Published: October 2022

Rasashastra is an important branch of Indian System of Medicine, which deals with the pharmaceutical processes, such as preparations of Bhasmas, Pistis, Kharaliya Rasayanas, Druti, Kupipakva Rasayanas, Parpati, Pottali. It is a well-known fact in the Ayurveda world that Bhasmas are highly efficacious and there are so many preparations of Tamra that are indicated for different ailments. Medicines (kalpas) mentioned in Rasa shastra are used freely in clinical practice by Ayurveda physicians after trial and testing. Now Ayurveda is accepted by world. Due to globalization, it is necessary to prove the Ayurveda drugs with modern parameters. So it can be utilized worldwide to get health. Hence the work taken here is preparation of Tamra Bhasma by two different methods and evaluating their effect on the Liver Function test pre-clinically. Tamra Bhasma preparation by two methods was chosen to compare the difference between direct heat and indirect heat method. Preparation with indirect heat by using sunlight method and with direct heat method resulted into bhasma. Biochemical and Histopathological changes in Liver were observed. Liver function assessment parameters namely serum Bilirubin, SGOT, SGPT, total protein were taken for biochemical evaluation. Also histopathology of Liver and Kidney was taken for study in support of biochemistry. The results were compared with standard drug Silymarine.
Gender wise consideration of Anguli Pramana in the present era
Authors: Visave Pratibha , Shukla Deepnarayan , Choudhari Deepali
Published: October 2022

Introduction: Anguli pramana is a unique concept in Ayurved. It was stated by acharyas at times when there was no any sort of standardised unit of measurements. Acharyas have mentioned Anguli pramana for various parts of the body. In respect of male and female gender, no separate anthropometric values found to be mentioned. Hence, the present study aimed at gender wise consideration of Anguli pramana. Method: After seeking ethical permission, 770 healthy participants of both gender between age group 18-50 years in Ahmednagar and Nashik region were selected for the study. Measurements were taken for selected body parts. The middle finger width of the right hand at proximal interphalangeal joint was used as a unit for Anguli pramana. Collected data treated with the Student’s t test for inference. Result: Measured values for selected parameters when compared with the standard values stated by acharya in both genders found statistically different except for a few i.e., Pad parinah and Pad vistar. Discussion: Variations in Anguli pramana may be due to evolutionary changes and lifestyle in the present era. The present study concluded that Anguli pramana is not valid in the present era. Its validity was checked according to gender separately. Though the findings are confined to the selected sample size and selected parameters, it could further be extended to arrive at generalization.
Observational Study of janu Pramana (knee) in various geographical regions of India
Authors: Gulhane Pavan R , Kulkarni Girish , Chandurkar Nitin
Published: October 2022

Context: Pramana Sharir (Anthropometry) is described as one of the tool to examine the patient and healthy individuals under the concept of dashvidh parikshabhava (tenfold examination) by Aacharya Charaka. Janu pramana (Knee joint measurement) is taken as one of the marker for sampramana (equal body measurement) which is 14 anguli in parinaha (circumference) cited by Aacharya Sushruta. Aim- the main aim of the study is to evaluate janu pramana (Knee joint measurement) in healthy individuals in this era. Methods and material- janu pramana (Knee joint measurement) of 400 healthy individuals from four geographical regions (100 from each region) of India was taken in four groups. Swanguali pramana (Individuals finger measurements) of individuals was taken with the help vernier callipers in centimeter and janu pramana was taken with the help of measuring tape in cm. Both this reading then converted into anguli pramana (Measurement tool by finger) and mean was drawn. Statistical analysis used- ANOVA test was used to draw the result. Result- it is observed that there is difference in the janu pramana stated by Aacharya Sushruta and janu pramana in this individuals and also there is difference in the janu pramana of individuals residing in different regions of India. Conclusion: This difference may be due to changing lifestyle and also due to some evolutionary changes. It may altered and affect the human anatomy.
Formulation and Evaluation of Polyherbal Anti-Dandruff Shampoo
Authors: More Anuradha G , Pote Priyanka D , Kore Padmaja S , Garhwani Yogish D
Published: October 2022

The Malassezia furfur fungal infection leads to dandruff formation. Dandruff cannot be fully eliminated but can only be effectively controlled. This study intends to formulate and evaluate the polyherbal anti-dandruff shampoo. The prepared formulation not only cleans the dirt and dandruff but also makes hair soft and lustrous and promotes hair growth. The formulation eliminates the use of harmful chemical ingredients that damages hair. The formulation uses various herbs like Neem, Bhringraj, Shikakai, Tulsi, Reetha, Aloe vera, Lemon juice, Orange peel, Ginger, Curry leaves, Hibiscus and other ingredients for preparing base shampoo which make an effective anti-dandruff formulation with smooth and shiny hairs, also provide conditioning and promotes hair growth. The formulated shampoo was subjected to evaluation parameters like visual inspection, pH, viscosity, dirt dispersion, surface tension, foaming ability, foam stability, antidandruff test and stability studies, etc. The major goal of the present study is to formulate and evaluate anti-dandruff shampoo for treating various hair issues. Dandruff  is  a  common  disorder  affecting  the  scalp  condition  caused  by  yeast  Pityrosporum.  Dandruff cannot be completely  eliminated but can  only be  managed and effectively controlled.  Shampoo is a  hair care product used for the removal of oils, dirt, skin particles, dandruff, environmental pollutants and other contaminant  particles  that gradually build up in  hair.  Herbal  anti-dandruff  shampoos were formulated using herbal based ingredients like Lemon Grass Oil, Neem oil, Henna, Aloe Vera gel and other ingredients for  preparing  base  shampoo.  The  formulated  shampoos  were  subjected  to  evaluation  parameters  like visual  inspection, pH, viscosity,  Percentage of solids  contents, Dirt dispersion,  Surface tension, Foaming ability and  foam stability.  The main  objective of this study was to eliminate harmful synthetic ingredient from anti-dandruff shampoo formulation and substitute them with a safe natural ingredients.
Evident experimental data of Habenaria longicorniculata J Graham on Cell mediated immunity - Promising source of Herbal immunomodulator
Authors: V Mallya Suma , B N Satish
Published: October 2022

Habenaria longicorniculata J. Graham from family Orchidaceae, are tuberous herbs, widely used by traditional physicians in the treatment of malignancy as a rejuvenator, immune boosters. Protocol designed to evaluate its In-vivo Immunomodulatory activity by cell mediated immunity. Materials and methods: Tubers were collected, cleaned, used for further study. In-vivo Immunomodulatory activity on rats for Assessment of immunity by Cell mediated Immunity, conducted as per the standard protocol. Results: Analysis of the results of the study indicates that the test drug Tubers possesses very good immunological oedema suppression effect.  Immunological oedema, represent expression of cell mediated immunity hence based on the results obtained these proved as best immunomodulators..
Pharmacognostical and biological evaluation of Mayurshikha (Actiniopteries dichotoma Bedd): An Ayurvedic medicinal plant
Authors: Patil Akshay , Gaonkar Vishakha P , Chimagave Supriya S , Hullatti Kirankumar
Published: October 2022

Aim: To evaluate pharmacognostical parameters and biological activities for Mayurshikha. Methods: The freshly collected plant material was subjected to pharmacognostical study followed by extraction and fractionation. Extract and fractions subjected for phytochemical investigation.The hydro-alcoholic extract and their four fractions were evaluated for in vitro antioxidant, antimicrobial, anthelmintic and brine shrimp lethality assay. The extract was subjected for fluorescence analysis. Total phenol content was estimated by Folin-Ciocalteu’s method. Results: The pharmacognostic study revealed the macroscopic characters, physicochemical constants and phytochemical nature of Mayurshikha. Phytochemical screening revealed the presence of lipids, phenols, terpenoids, sterols, alkaloids and flavonoids.Total phenol content was found to be 6.36 µg/mg of Gallic acid equivalents GAE/g. In vitro biological activities were performed to assess the biological efficacy. Fraction 4 showed promising antioxidant activity with IC50 of 1.49µg/ml. Amongst four fractions, F3 and F4 showed pronounced antimicrobial activity with minimum inhibitory concentration of 100µg /ml. Fraction 3 showed better anthelmintic activity as death time for same fraction was 4.78(±0.93) minutes. Further, with the LC50 value of 1.49µg/ml, Fraction 3 was found to exhibit better cytotoxicity amongst all fractions. Conclusion: From the above finding it clearly indicates that Mayurshikha consists of active phytoconstituents which can be utilized for therapeutic purpose.
A Literary review on Buddhi(IQ) and Smriti(Memory)–An Ayurveda approach
Authors: Japang Ibamedabha , Rathi Renu B , Verma Jitesh , Dwivedi Prakash
Published: October 2022

Mana (mind) is one of the important things in life which leads to overall health. Smriti (memory) is the remembrance of what has been experienced directly earlier. It is described as one among the eight Aishwaryas (desire of power) which only happen through the concentration of the mind. Buddhi (Intellect) is also known as Mahata (greatness), Upalabidhi (accomplishment), and Gyana (intellectual). Grahana (grasping) and Dharana (retaining) capacity are the most important properties of intellect because of this knowledge can be retrieved by Smriti (memory). In the modern era due to stress, and disturbing emotions there is an increase in incidences of psychosomatic disease. Aim and objectives: The main aim is to explore and review IQ and memory through the Ayurveda approach. Materials and methods: The source for this study is collected from the classical Ayurvedic books and commentaries, modern medical science textbooks and different articles from Pubmed, DHARA, Google scholar etc. Result:  There is an elaborate description of various mental faculties like Buddhi (intellect), Manas (mind), and Smriti (memory) in the ancient Indian texts including Ayurveda texts. Conclusion: Exploration of IQ and memory through the Ayurveda approach helps better understanding of IQ and memory which can improve the practical utility and clinical applicability of these Ayurvedic concepts. Clinically, the anatomic and physiologic knowledge of both IQ and memory will not only facilitate choosing the right medicinal formulations but also definite Panchakarma procedures for the best outcome in the prevention of diseases and cure the neuromotor or neuro-behavioural ailments in which both IQ and memory get defected.
A Holistic Approach on Duchenne Muscular Dystrophy by Ayurvedic Treatment Modalities along with Traction: A Case Report
Authors: Rudey Megha Dipak , Rathi Renu , Rathi Bharat
Published: October 2022

Background & Objectives- Duchenne muscular dystrophy (DMD) is individual and one of the most communal and serious condition come under childhood muscular dystrophies. The incidence of DMD is 1:3500 births of males. It is an X-linked recessive disorder that occurs due to deletion or alteration of dystrophin protein, which is encoded by DMD Gene on Xp21 chromosome. As per the view of Ayurveda, we can consider this disorder as chromosomal hereditary anomalies (Bheejabhagahaavyava dushti janya Adibalapravtrutta vyadhi). Main objective of this case report was reduce the complaints of patient and improve the quality of life. Method and Material- The present study is about the management of DMD as per Ayurveda perspective. An 11 years old male child, has complaints of difficulty in walking, frequent falls while walking, difficulty in sitting or squatting. On Ayurvedic management principles, the present case was managed with palliative care (Shaman) and bio-cleansing therapy (ShodhanChiktsa). Result- After treatment, there was a significant improvement in complaints with signs and symptoms. Interpretation and conclusion- Though we are unable to rule out the disposition of genes through Ayurveda treatment modalities such as internal medicines, 5 detoxification procedures (Panchakarma) procedures, traction etc. we can effectively prolong the deterioration and improve the quality of life with correction in diet and lifestyle as per Ayurveda principles.
Evaluating the Stress Factors of Dermatology Nurses during the COVID-19 pandemic in Vietnam
Authors: Vu Thu-Trang , Vu Dung , Phan Hoang-Trong , Pham Tien-Nam , Nguyen Hung-Hoa , Thai Thu-Hang
Published: October 2022

Objectives: Nursing is among the top three most stressful jobs, yet stress in nurses has diminishing impacts on their personal health and productivity. The COVID-19 pandemic might elevate stress in nurses, in particular dermatology nurses. This study aims to examine the prevalence of stress among dermatology nurses and its related factors. Methodology: A cross-section study was conducted among 154 nurses at the National Hospital of Dermatology and Venereology in Vietnam. Data were collected during the third cluster of COVID-19 pandemic spread in Hanoi. Nurse stress was measured by stress items of the DASS-21. Factors related to stress included personal, family, work-related and social factors. Results: 51.9% of nurses met the criteria for stress according to DASS-21. All nurses reported at least 1 symptom of stress in the past week. Factors significantly related to stress among nurses included personal, family, work-related and social factors. While many factors in these four groups created stress in nurses, only work-related and social factors elevated the severity of stress in nurses. Conclusion: Hospital management should develop strategies to support nurses deal with stress, since most of the factors that elevate stress can be addressed by system-level interventions, such as management of professional relationships, organizational justice, and the welfare system.
Case Study on Regional Original Income: Analysis of Effectiveness, Efficiency, Fiscal Decentralization, and Regional Financial Dependence Ratio
Authors: Juliarti Anisa , Hariyanto Dedi , Meutianingrum Farah Juniati
Published: October 2022

This study aims to analyze the financial performance of the Kubu Raya Regency Government using the Effectiveness Ratio Analysis, Efficiency Ratio, Fiscal Decentralization Ratio, and Regional Financial Dependency Ratio. This study uses quantitative research, with secondary data in the form of the Kubu Raya Regency Government Budget Realization Report 2018-2020 obtained using a documentation study. The results showed that the Effectiveness Ratio resulted in an average of 101.12%, which means that it is classified as very effective. Furthermore, the Efficiency Ratio is 86.08%, which means that it is classified as an efficient criterion. Then the Fiscal Decentralization Ratio is 33.34%, which means that it is classified as moderate. And the average Regional Financial Dependency Ratio is 79.13%, which means it is classified as very high criteria. The implication of the results of this study is that the Kubu Raya Regency Government should further explore the existing regional potential in order to increase PAD, so as to reduce regional financial dependence in the implementation of fiscal decentralization in the following years.
Dyslexia and Foreign Language Learning
Authors: Sadry Zahra , Momand Muska , Hairan Mohammad Haroon
Published: October 2022

This study investigates the concept of dyslexia, the nature of problems and challenges that dyslexic student encounter during their studies, possible opportunities and the strategies how to support dyslexic language learners. Through conducting online research and review, it has been revealed that dyslexia is not a stigma nor a severe illness, though it was believed so, but it disclosed how one’s brain can work differently and creatively than others’. Educators and parents have important roles in helping and supporting dyslexic students. Teachers should keep in mind that their helpful encouragement of dyslexic students in their learning process can support them in managing their study and learning habits
O USO DA CARBAMAZEPINA E DA LAMOTRIGINA NO TRATAMENTO DA NEURALGIA DO TRIGÊMEO
Authors: Castilhos Silva Caroline , Lacerda da Silva Juana
Published: October 2022

Objetivo: Realizar um levantamento bibliográfico sobre a Neuralgia do Trigêmeo e o uso dos fármacos Carbamazepina e Lamotrigina no seu tratamento. Métodos: Foi realizada uma busca e seleção de artigos científicos que abordassem a temática do assunto, ‘’o uso dos medicamentos Carbamazepina e Lamotrigina no tratamento da neuralgia do trigêmeo’’. Os descritores selecionados para a busca foram: “neuralgia do trigêmeo” (trigeminal neuralgia), ‘’Carbamazepina’’ (Carbamazepine) e “Lamotrigina” (Lamotrigine). No período de junho a agosto de 2021 foi realizada uma busca nas bases de dados eletrônicas Scielo e PubMed, além de busca ativa em referências. Resultados: Foram avaliados 21 artigos e 5 livros, dentro da temática dos descritores, e realizada uma revisão integrativa de literatura. 20%  caracterizou a Carbamazepina (CBZ) como padrão ouro na terapia, 5% apontou a CBZ não eficaz no tratamento, 10% caracterizou a Lamotrigina (LTG) como boa opção de tratamento, 5% apontou que a LTG não apresenta lugar significativo na terapêutica, 5% utilizou outro fármaco antiepiléptico como tratamento, 45% apontou que tanto a doença quanto as formas terapêuticas devem ser melhor estudadas para evidenciar  veracidade de forma eficaz de tratamento e 10% caracterizou a concordância de primeira e segunda linha de tratamento da CBZ e LTG respectivamente. Considerações Finais: A neuralgia do trigêmeo é uma doença extremamente debilitante, que afeta o meio biopsicossocial do paciente, por se tratar de uma doença relativamente rara, muitos cirurgiões-dentistas não têm o conhecimento dos tipos de terapêutica da patologia.
A Systematic Review on an Optimal Dose of Disaster Preparedness Intervention Utilizing Health Belief Model Theory
Authors: Mhd Noor Mohd Tariq , Shahar Hayati Kadir , Baharudin Mohd Rafee , Syed Ismail Sharifah Norkhadijah , Abdul Manaf Rosliza , Md Said Salmiah , Ahmad Jamilah , Muthiah Sri Ganesh
Published: October 2022

Disaster preparedness is an issue that receives little attention in the community. Communities must take preventative measures to overcome obstacles and improve community preparedness. This review identifies the optimal dose of disaster preparedness intervention in the community. A systematic literature search was conducted to examine a study about the optimal dose of disaster preparedness intervention developed for implementation at a community level. A scoping review based on the PRISMA diagram was conducted from four databases. A combination of keywords was adapted for each database. Inclusion and exclusion criteria were applied. A total of eight articles were synthesized based on the intervention dose of disaster preparedness among community interventions. The summarized studies provided evidence that the optimal dose for disaster preparedness intervention in the community can be prevented with an educational intervention program with a minimal dosage of intervention. The Health Belief Model Theory was the most often cited theory by researchers. The best dose for disaster preparedness intervention in a community can be mitigated with a single dose of education. Nonetheless, we cannot disregard alternative disaster preparedness theories because each has its advantages and disadvantages.
The state-legal personality of the Republic of Serbian Krajina
Authors: Brekalo Miljenko , Adanić Stjepan
Published: October 2022

From its foundation until its end, the Republic of Serbian Krajina
(the RSK) had been a parastate, remaining the parastate, having
failed to meet any criteria of a normally functioning state, as prescribed by Montevideo Convention on the Rights and Duties of
States, known as Montevideo Convention. Therefore, the RSK has
never become the subject of international law, unlike the Republic of Srpska, upon signing The General Framework for Peace
in Bosnia and Herzegovina or the Dayton Peace Agreement. The
Republic of Serbian Krajina was a federative parastate, defined by
the territorial discontinuity and it consisted of three federative units:
the Serbian Region of Slavonia, Baranja and Western Sirmium
Region, the Serbian Region of Western Slavonia and the Serbian
Autonomous Region of Krajina. In the formal and legal sense, the
Republic of Serbian Krajina was established after it got proclaimed on 19th December 1991. However, it fell apart, de facto, on
5th August 1995, due to the fact that its capital city of Knin, was
liberated by the joined police and Croatian military forces, compelling the RSK representatives to sign the capitulation, de iure, on
8th August 1995.
Keywords: state; parastate; nation; territory; government; a subject of the international law.
The study of urban form in Lithuania during the second half of the twentieth century
Authors: Alistratovaitė-Kurtinaitienė Inesa , Dijokienė Dalia , Cirtautas Matas
Published: October 2022

This paper discusses one of the most significant and productive periods of urban form studies in Lithuania. Research activities during the second half of the twentieth century, compared to the evolutionary stages of other urban morphological schools in Europe, represent a period of mature development. Research activities can be divided into three phases which followed each other and later overlapped: emergence of morphological thought in the primary studies of settlements; development of a morphological approach within the formation of the national urban heritage system; and application of morphological techniques for modelling the spatial composition of towns and cities. Despite its local focus, the Lithuanian urban form research has the potential to complement the global landscape of urban morphology and contribute to the development of the field’s scientific and practical methodology. Therefore, the paper presents the development of national tradition of urban morphology, which evolved throughout the twentieth century, as well as comparing the Lithuanian experience with features of other European morphological schools.
The urban form of ancient Chinese capital cities
Authors: Liu Cui , Jin Luoyu , Yao Ji , Zhang Yiting , Guo Yiyao , Oliveira Vítor
Published: October 2022

Chinese civilization is unique in terms of longevity, lasting from the late-third millennium BC to the twenty-first century, without interruption. Despite the recent interest on Chinese urban form, knowledge on the subject remains insufficient, lacking both a comprehensive framework and particular contributions on different aspects of its urban forms, agents, and processes of change. This paper addresses the second of these two challenges, contributing to the morphological description and explanation of ancient Chinese capital cities, specifically, the so-called four great Ancient Capitals of China – Luoyang, Xi’an, Nanjing, and Beijing. Due to the scarcity of sources and the complexity of these cities, the paper proposes a simplified analysis of the town plan, including the reading of street systems, plot patterns and building arrangements. This simplified analysis of the town plan can be used as a first approach to understand the physical form of a city. A comparison between the four cities is offered, identifying what is ‘particular’ about them and what is ‘general’, or common, to other ancient Chinese capital cities.
The city and citizens: A happy symbiosis (in search of existential happiness)
Authors: Lidin Konstantin
Published: October 2022

The perception of the city as a living organism raises the question of its symbiosis with citizens. Like any living organism, the city has its own needs and development goals, which must be consistent with the needs of its inhabitants. Theoretical psychology has formulated a hierarchy of needs. They develop from the simplest, universal for all living things, to the highest existential needs inherent in the most highly developed personalities. Most urban theories consider the city at the level of primary needs no higher than the second stage (the need for security). At present, attempts are being made to build a theory of the symbiosis of the city and citizens at the highest levels of existential needs.
Conversion of the Kedr distillery into a creative cluster
Authors: Fomina Olga , Druzhinina Inna
Published: October 2022

The author considers the reasons for degradation of the territory of Kedr distillery in Irkutsk and possibilities of preservation of the abandoned territory and transformation of a rare historical and town-planning industrial complex of the Baikal Region. The potential of the territory of the distillery and the Znamensky district is revealed through the formation of a single public centre for the development of creative industries in Irkutsk.
Youth Centre in the historical quarter 108 in Irkutsk
Authors: Khvostantseva Diana , Druzhinina Inna
Published: October 2022

The authors tried to solve the general composition of the quarter and the internal organization of the multifunctional centre in harmony with the surroundings, as well as to realize the main idea: to build a new progressive building for young people in the capital of the Angara region, a centre for intellectual, professional and creative growth.
Multiple cerebral arterial dissections with a ruptured blister aneurysm after COVID-19 vaccination: a case report
Authors: Kim Sum , Jeon Hong Jun , Lee Jong Young , Cho Byung Moon
Published: October 2022

Although extensive clinical data have verified the safety and adverse effects of coronavirus disease 2019 (COVID-19) vaccines, unexpected neurovascular events have rarely been reported. This report presents an unusual case in which we inferred that spontaneous multiple cerebral arterial dissections with a ruptured blister aneurysm occurred after COVID-19 vaccination. A 34-year-old woman presented with a severe headache, confusion, and mild weakness in her left arm 18 days after having received the Pfizer-BioNTech COVID-19 vaccine. Digital subtraction angiography showed fusiform dilatation in the proximal part of the left vertebral artery and luminal irregularities and string signs in the distal V4 segment. Stroke after vaccination involving multiple cerebral arterial dissections and simultaneous rupture of a blister aneurysm is a very rare phenomenon. Although laboratory studies such as cytoplasmic anti-neutrophil cytoplasmic autoantibody, perinuclear anti-neutrophil cytoplasmic antibodies, anti-cardiolipin, rheumatoid factor and lupus anticoagulant were checked in order to screen the patient for vasculitis and fibromuscular dysplasia, none of them showed significant results. The Pfizer-BioNTech COVID-19 vaccine that the patient had received a few days ago was the only plausible trigger. In conclusion, COVID-19 vaccination might lead to multiple cerebrovascular changes in a short period of time.
Real-Time Continuous Glucose Monitoring: A Review of Guidelines
Authors: Barbara Angela M. , Grobelna Aleksandra
Published: October 2022

Six evidence-based guidelines regarding the use of real-time continuous glucose monitoring in people living with type 1 or type 2 diabetes were included in this report. Three included guidelines were of high quality, while 3 guidelines were of moderate quality due to unclear reporting of methodological details.

Four evidence-based guidelines strongly recommended the use of real-time continuous glucose monitoring in adults for the management of type 1 diabetes, based on intermediate- to high-quality evidence.

Four guidelines recommended real-time continuous glucose monitoring for adults living with type 2 diabetes, based on low- to high-quality evidence.

Three guidelines strongly recommended the use of real-time continuous glucose monitoring in children and young people living with type 1 diabetes, based on intermediate- to high-quality evidence.

One guideline recommended real-time continuous glucose monitoring for children and young people with type 2 diabetes, based on expert consensus rather than evidence of clinical effectiveness.