bluuebunny/crossref_metadata_2025 huggingface dataset:
PyRates—A code-generation tool for modeling dynamical systems in biology and beyond
Authors: Gast Richard , Knösche Thomas R. , Kennedy Ann
Published: December 2023

The mathematical study of real-world dynamical systems relies on models composed of differential equations. Numerical methods for solving and analyzing differential equation systems are essential when complex biological problems have to be studied, such as the spreading of a virus, the evolution of competing species in an ecosystem, or the dynamics of neurons in the brain.

Here we present PyRates, a Python-based software for modeling and analyzing differential equation systems via numerical methods. PyRates is specifically designed to account for the inherent complexity of biological systems. It provides a new language for defining models that mirrors the modular organization of real-world dynamical systems and thus simplifies the implementation of complex networks of interacting dynamic entities. Furthermore, PyRates provides extensive support for the various forms of interaction delays that can be observed in biological systems.

The core of PyRates is a versatile code-generation system that translates user-defined models into “backend” implementations in various languages, including Python, Fortran, Matlab, and Julia. This allows users to apply a wide range of analysis methods for dynamical systems, eliminating the need for manual translation between code bases.

PyRates may also be used as a model definition interface for the creation of custom dynamical systems tools. To demonstrate this, we developed two extensions of PyRates for common analyses of dynamic models of biological systems: PyCoBi for bifurcation analysis and RectiPy for parameter fitting. We demonstrate in a series of example models how PyRates can be used in combination with PyCoBi and RectiPy for model analysis and fitting. Together, these tools offer a versatile framework for applying computational modeling and numerical analysis methods to dynamical systems in biology and beyond.
Redundant microtubule crosslinkers prevent meiotic spindle bending to ensure diploid offspring in C. elegans
Authors: Li Wenzhe , Crellin Helena A. , Cheerambathur Dhanya , McNally Francis J.
Published: December 2023

Oocyte meiotic spindles mediate the expulsion of ¾ of the genome into polar bodies to generate diploid zygotes in nearly all animal species. Failures in this process result in aneuploid or polyploid offspring that are typically inviable. Accurate meiotic chromosome segregation and polar body extrusion require the spindle to elongate while maintaining its structural integrity. Previous studies have implicated three hypothetical activities during this process, including microtubule crosslinking, microtubule sliding and microtubule polymerization. However, how these activities regulate spindle rigidity and elongation as well as the exact proteins involved in the activities remain unclear. We discovered that C. elegans meiotic anaphase spindle integrity is maintained through redundant microtubule crosslinking activities of the Kinesin-5 family motor BMK-1, the microtubule bundling protein SPD-1/PRC1, and the Kinesin-4 family motor, KLP-19. Using time-lapse imaging, we found that single depletion of KLP-19KIF4A, SPD-1PRC1 or BMK-1Eg5 had minimal effects on anaphase B spindle elongation velocity. In contrast, double depletion of SPD-1PRC1 and BMK-1Eg5 or double depletion of KLP-19KIF4A and BMK-1Eg5 resulted in spindles that elongated faster, bent in a myosin-dependent manner, and had a high rate of polar body extrusion errors. Bending spindles frequently extruded both sets of segregating chromosomes into two separate polar bodies. Normal anaphase B velocity was observed after double depletion of KLP-19KIF4A and SPD-1PRC1. These results suggest that KLP-19KIF4A and SPD-1PRC1 act in different pathways, each redundant with a separate BMK-1Eg5 pathway in regulating meiotic spindle elongation. Depletion of ZYG-8, a doublecortin-related microtubule binding protein, led to slower anaphase B spindle elongation. We found that ZYG-8DCLK1 acts by excluding SPD-1PRC1 from the spindle. Thus, three mechanistically distinct microtubule regulation modules, two based on crosslinking, and one based on exclusion of crosslinkers, power the mechanism that drives spindle elongation and structural integrity during anaphase B of C.elegans female meiosis.
“I hope I die. That is what I hope for”: Qualitative study of lived experiences of mental health of Indian women living with HIV experiencing intersectional stigma
Authors: Mukerji Reshmi , Mannell Jenevieve , Osrin David
Published: December 2023

Poor mental health due to stigma and discrimination has been well documented among women living with HIV. Although they often have other marginalized and stigmatized identities, little is known about their mental health as a result of experiencing multiple stigmas. Current narratives of mental health as a result of HIV-related stigma center on common mental health disorders such as anxiety and depression. However, biomedical diagnostic categories may not be as well known in all cultural and social contexts, and people may choose to express their distress in their own language. It is therefore important to listen to how women express their mental health concerns in their own language—their lived experiences—in order to best support them. To fill this research gap, semi-structured interviews were conducted in Kolkata, India, with 31 women living with HIV and 16 key informants. Data were coded and analyzed using thematic network analysis. The results showed that women suffered from poor mental health, which in turn affected their physical health. This happened through reduced adherence to medication, lowered CD4 counts, and the physical effects of stress, which could be perceived as prolonged. Participants described women’s mental health concerns as worry, sadness, hopelessness, and fear, but biomedical diagnostic labels were rarely used. This allowed women to avoid additional stigmatization due to mental illness, which can attract some risk in this social context. As many women living with HIV experience poor mental health, they should be supported with a combination of psychosocial and psychological interventions. These include screening all women for mental illness and offering them mental health first aid. Those requiring additional support should be offered specialist psychotherapeutic and pharmacological care. This must be accompanied by stigma reduction interventions if they are to be successful in addressing the mental health needs of women living with HIV.
The influence of college students’ aesthetic cognitions on aesthetic behaviours: The Chain mediation effect
Authors: Qiao Qiao , Jiang Yongzhi
Published: December 2023

This research investigates the psychological and behavioural mechanisms of college students’ aesthetic behaviours. A survey was administered to 1,060 students attending general undergraduate universities and measured four structured scales: aesthetic cognition, aesthetic emotion, aesthetic value tendency and aesthetic behaviour. The responses were scored with a 5-point Likert scale. Structural equation modelling was used to construct the measurement model and structural model. The survey results indicate a positive correlation among the four variables. Second, aesthetic cognition has a direct and positive predictive effect on college students’ daily aesthetic practices. Furthermore, aesthetic cognition influences aesthetic behaviour through the chain mediating effect of aesthetic feeling and aesthetic preference. Accordingly, we conclude that the concrete path and mechanism of college students’ aesthetic cognitions affect their aesthetic behaviours. Specifically, college students’ aesthetic cognitive abilities are conducive to their cognitions of positive aesthetic feelings and their cultivation of aesthetic standards, boosting the development of their daily aesthetic practice.
Development of a robust daily soil temperature estimation in semi-arid continental climate using meteorological predictors based on computational intelligent paradigms
Authors: Alizamir Meysam , Ahmed Kaywan Othman , Kim Sungwon , Heddam Salim , Gorgij AliReza Docheshmeh , Chang Sun Woo
Published: December 2023

Changes in soil temperature (ST) play an important role in the main mechanisms within the soil, including biological and chemical activities. For instance, they affect the microbial community composition, the speed at which soil organic matter breaks down and becomes minerals. Moreover, the growth and physiological activity of plants are directly influenced by the ST. Additionally, ST indirectly affects plant growth by influencing the accessibility of nutrients in the soil. Therefore, designing an efficient tool for ST estimating at different depths is useful for soil studies by considering meteorological parameters as input parameters, maximal air temperature, minimal air temperature, maximal air relative humidity, minimal air relative humidity, precipitation, and wind speed. This investigation employed various statistical metrics to evaluate the efficacy of the implemented models. These metrics encompassed the correlation coefficient (r), root mean square error (RMSE), Nash-Sutcliffe (NS) efficiency, and mean absolute error (MAE). Hence, this study presented several artificial intelligence-based models, MLPANN, SVR, RFR, and GPR for building robust predictive tools for daily scale ST estimation at 05, 10, 20, 30, 50, and 100cm soil depths. The suggested models are evaluated at two meteorological stations (i.e., Sulaimani and Dukan) located in Kurdistan region, Iraq. Based on assessment of outcomes of this study, the suggested models exhibited exceptional predictive capabilities and comparison of the results showed that among the proposed frameworks, GPR yielded the best results for 05, 10, 20, and 100cm soil depths, with RMSE values of 1.814°C, 1.652°C, 1.773°C, and 2.891°C, respectively. Also, for 50cm soil depth, MLPANN performed the best with an RMSE of 2.289°C at Sulaimani station using the RMSE during the validation phase. Furthermore, GPR produced the most superior outcomes for 10cm, 30cm, and 50cm soil depths, with RMSE values of 1.753°C, 2.270°C, and 2.631°C, respectively. In addition, for 05cm soil depth, SVR achieved the highest level of performance with an RMSE of 1.950°C at Dukan station. The results obtained in this research confirmed that the suggested models have the potential to be effectively used as daily predictive tools at different stations and various depths.
Molecular characterization of mitochondrial COI gene sequences in Micraspis allardi from Pakistan
Authors: Asrar Rida , Masood Mariyam , Bodlah Imran , Rasool Ghulam , Suleman Nazia , Yousaf Sumaira
Published: December 2023

The Coccinellidae is a highly diversified family of order Coleoptera. Coccinellid ladybirds are well known for their role as biological control agent against varied range of agricultural pests. The samples of coccinellid ladybird collected from Pakistan were identified and characterized as Micraspis allardi (Mulsant, 1866). This is one of the least-studied ladybird species with limited work on its ecological distribution as a biological control agent. The genus Micraspis has vast genetic diversity with a possible presence of unknown number of cryptic species. Sequence information of some species of the genus Micraspis are present in NCBI database. However, least molecular data or sequences describing M. allardi could be available from database. Therefore, morphological and molecular characterization was imperative for this species. Here, the samples collected from sugarcane field of Faisalabad District of Pakistan and were identified by using morphological and molecular protocols. For molecular identification, two different regions of mitochondrial cytochrome c oxidase I (COI) gene (COI-5′ and COI- 3′) were used as molecular markers for the identification of the species. Morphological appearance, DNA sequence similarity searches and phylogenetic analysis collectively indicated it as M. allardi. To the best of our knowledge, this is the first report providing molecular evidence of M. allardi using mitochondrial DNA barcode region (658bp) as well as mtCOI-3ʹ sequences (817bp). The study will help in understanding population genetics through diversity analysis, ecological role, and phenotypic structures associated with the geographic range of this species.
Similar functional composition of fish assemblages despite contrasting levels of habitat degradation on shallow Caribbean coral reefs
Authors: Olán-González Manuel , Briones-Fourzán Patricia , Lozano-Álvarez Enrique , Acosta-González Gilberto , Alvarez-Filip Lorenzo
Published: December 2023

Functional trait-based approaches provide an opportunity to assess how changes in habitat affect the structure of associated communities. Global analyses have found a similarity in the composition of reef fish functional traits despite differences in species richness, environmental regimes, and habitat components. These large-scale patterns raised the question of whether this same stability can be observed at smaller spatial scales. Here, we compared the fish trait composition and their functional diversity in two Caribbean shallow coral reefs with contrasting levels of habitat degradation: Limones (>30% cover), constituted mainly by colonies of Acropora palmata and Bonanza, a reef with extensive areas of dead Acropora structures, dominated by algae. To characterize the functional structure of fishes on each reef, we calculated the community-weighted mean trait values (CWM), functional richness, functional evenness, functional dispersion, and functional originality. Despite the differences in habitat quality, reefs exhibited a similar proportion and common structure on fish functional traits. Functional richness and functional evenness differed significantly, but functional dispersion and functional originality did not show differences between reefs. The greater niche complexity driven by the high availability of microhabitats provided by A. palmata may explain the higher functional richness in Limones, whereas the reef degradation in Bonanza may contribute to a higher functional evenness because of a similar distribution of abundance per fish trait combinations. Our results suggest that widespread degradation on Caribbean reefs has limited the type, variety, and range of traits, which could lead to a functional homogenization of fish communities even at local scales.
Systematic review of end stage renal disease in Pakistan: Identifying implementation research outcomes
Authors: AlRashed Hamad , Miele Johanna , Prasad Joshua , Adenikinju Deborah , Iloegbu Chukwuemeka , Patena John , Vieira Dorice , Gyamfi Joyce , Peprah Emmanuel
Published: December 2023

Aim and objectives

The aim of this study was to conduct a systematic review analysis to identify and evaluate the available literature on implementation science outcomes research in relation to End Stage Renal Disease (ESRD) in Pakistan.

Methods

A systematic database search of PubMed, Web of Science, EMBASE, Cochrane Library, CINAHL, and Ovid was conducted through October 22nd, 2022, without any restrictions on publication dates. A screening and data extraction tool, Covidence, was used to evaluate the literature against our inclusion and exclusion criteria. Furthermore, a Mixed Methods Appraisal Tool (MMAT) was used to evaluate the selected studies.

Results

We identified four studies that presented findings of implementation outcomes research which were related to appropriateness, feasibility, and acceptability. Appropriateness was examined using knowledge scores (p = 0.022) and medication adherence scores (p < 0.05) that showed statistical significance between the control and intervention groups. Acceptability was assessed through a cross sectional quantitative descriptive study that evaluated the reasons for refusal and acceptance of treatment in a cohort of patients suffering from ESRD. Feasibility was examined in one cross sectional, and one mixed methods study that aimed to evaluate and understand the impact of initiating dialysis treatment and the feasibility of maintaining it in low-income families that care for children or adults with ESRD.

Conclusion

The preliminary results of this review indicate a gap in the availability of implementation research studies about ESRD in Pakistan. The burden of ESRD, and the implementation methods by which it is treated is notable in Pakistan and requires evidence-based measures to be implemented to support the critical healthcare delivery platforms that provide treatment.
Of monsters and men: Physical attractiveness and the appearance of monstrosity in Netflix’s You
Authors: Kopitz Linda
Published: December 2023

The series You, which has become part of the cultural zeitgeist since the first season became available on Netflix in December 2018, has introduced a protagonist at the same time in line and notably different from other serialized serial killers. By establishing the main character, played by former Gossip Girl heartthrob Penn Badgley, not only as the protagonist but romantic lead in a format blurring conventions from both the psychological thriller and the romance, the series challenges viewers to negotiate their attraction for a television character that seems ‘unloveable’. Portrayed as both a (literal) stalker and serial killer in the series, how viewers talk about Joe Goldberg underlines an understanding of the contemporary monstrous body as a site of manifestation. Through a discourse analysis of comments posted on Twitter and YouTube about the show and its main character, this article highlights how viewers interrogate questions of monstrosity and morality through the visuality of the body. As an interpretive repertoire centred on Embodiment, highlighting the attractive and non-threatening body functions as a practice of meaning-making that is aware of, but does not necessarily follow an ‘intended’ reading by the producers of popular culture.
Historically informed costume: Collaborative practice between maker, historian and performer
Authors: Dotlačilová Petra , Kjellsdotter Anna
Published: December 2023

This article offers a new view on ‘period’ or – as we propose to call it – ‘historically informed’ costume. We consider ‘historically informed’ costume a product of a specific mode of creation, but also and especially a process of research, which brings new insights both into the history of costume and performance. After a brief overview of approaches to period costume through the twentieth century, and its use in ‘historically informed performance’, we present a methodology developed through five years of collaboration between costume maker, historian and performers within the research project Performing Premodernity. This methodology employs comparative research of material, visual and textual sources, and making and performing experiments, often in historical spaces. It stresses an experimental and collaborative approach to research and creation, in which each member brings their expertise and way of doing that complement one another. Furthermore, the methodology promotes connections between objects – costumes and bodies – which inform each other through the historicity of their practice.
Making history, one stitch at a time: A conversation with Trish Butterworth
Authors: Anderson Margot
Published: December 2023

Trish Butterworth was part of the Opera Australia wardrobe department for over forty years. She joined the company in the 1970s and worked under the direction of William Paterson who set the benchmark for top-quality workmanship at an exciting time in the Australian Opera’s history. In 2019, Opera Australia donated 30 costumes worn by Dame Joan Sutherland to the Australian Performing Arts Collection. It was largely thanks to Trish that these costumes had survived amidst the busy environment of a working wardrobe over many decades. Carving out snippets of time under the pressure of meeting tight deadlines, Trish had quietly ensured Sutherland’s costumes were kept safe in a dedicated room at the heart of the company’s headquarters in Sydney. This conversation document focuses on the strong connection Trish formed with Paterson to realize the vision of designers such as Kristian Fredrikson, Michael Stennett and Desmond Digby during the 1970s and 1980s when Sutherland was performing regularly with the company. It also highlights the bond between maker and costume, reflecting on how the costumes were made and why Trish dedicated so many precious hours to preserving what Sutherland considered to be ‘some of the most beautiful costumes I have ever seen’.
Un comerciante riojanoburgalés en el emporio bilbaíno durante la transición del antiguo régimen al liberalismo: Ángel Martínez Vítores (1781-1847)
Authors: Martín García Juan José , Martínez De Sas María Teresa
Published: December 2023

Analizando el recorrido vital del comerciante Ángel Martínez confirmamos capítulos de la Historia Contemporánea española que, no por estudiados, están suficientemente agotados. Su trayectoria discurrió en una época convulsa de crisis políticas, económicas y sociales a las que tuvo que adaptarse. Testigo de lo que se ha dado en llamar la caída del Antiguo Régimen, reflejó los tópicos que acompañaron al segmento social al que pertenecía. Facetas modernas combinadas con otras tradicionales que, como hombre de transición, no pudo soslayar.
Entrepreneurship and Small Businesses Management; Growing and sustaining successful small businesses: strategies and case studies
Authors: Abbas Nour , Henaine Anna Maria , Sabra Rana , Hatem Georges
Published: December 2023

Background: Entrepreneurship boosts economic growth by introducing innovative technologies, products, and services. Lebanese entrepreneurs face many challenges when starting their ventures, especially in the pharmaceutical field. It’s important to understand these challenges to provide adequate strategies for small business development and maintain the sustainability and growth of such businesses.

Objectives: The study was done during the COVID-19 pandemic and the Lebanese economic crisis in 2020. The aim was to address the entrepreneurs in Lebanon's pharmaceutical sector and evaluate the strategies they adopt before and after launching their small businesses and the skills they should have and develop to maintain their businesses.

Methods: A descriptive study based on qualitative research was conducted in Lebanon over one month. An online survey collected data from Lebanese pharmapreneurs owning small businesses. Data collection and analysis were performed on Microsoft Excel.

Results: Most entrepreneurs were interested in the field they invested in. They learned new skills, adopted new strategies, invested effectively in the available resources, and developed leadership skills to sustain their businesses during the economic crisis and COVID-19 pandemic. Besides, most participants did SWOT, market, and feasibility analyses before starting their business. To induce business growth, entrepreneurs followed many strategies to grow their business: planning and management, market research, taking risks, choosing the proper business model, and applying digital marketing strategies. Many personal skills, such as trustworthiness, patience, dedication, and hard work, guarantee an entrepreneur’s success.

Conclusion & recommendations: The pharmaceutical field in Lebanon is facing many challenges. The Lebanese government and the Lebanese order of pharmacists must take serious steps to support small businesses. Pharmapreneurs must be aware of the challenges they face and adopt appropriate strategies to support their businesses.
Ovarian mass with gall bladder stone reported in young female patient, this case support the ovarian gallbladder axis theory
Authors: Elrobaa Islam , Elmoheen Amr , Mohamed Eslam , Nassani Hajar , Alrefi Tarek
Published: December 2023

A 33 years old female patient presented to our ED for epigastric pain and lower abdominal pain , the pain was almost in left side with tenderness on right side . The patient had multiple visit before to primary health care for lower abdominal pain and epigastric pain , she got many of medications but no improvement . She had regular menstruation, last menstrual period was 15 day before that visit to our ED . Blood test was requested that showed normal liver , renal and pancreatic function , only she had mild elevated in WBs about 11000 and mild elevated in CRP about 17 . At that time , the patient still has had lower abdominal pain and epigastric pain , SO CT abdomen requested to rule out acute appendicitis.The CT abdomen Showed :gallbladder stone and right ovarian large cystic lesion with solid component , free fluid intra abdomen and no appendicitis . The ultrasound abdomen requested for more details about the cystic ovarian lesion that showed : Right adnexal cystic lesion with solid component / right ovarian hemorrhagic cyst with retracting clot. Minimal ascites. Uncomplicated cholecystolithiasis . tumours marker requested that was much elevated . The Patient flew back to her country for medical management up on her request
How to attract the best possible executive to be your new CEO
Authors: Riess Victoria
Published: December 2023

The two information asymmetry problems I face in hiring my next CEO are adverse selection and moral hazard. Information asymmetry problems arise when two parties have different levels of information. For example, if an employer hires an employee, each party has information which the other does not have. The employer knows the difficulty of how the work is to manage but the employee knows what amount of work he is willing to contribute. This is called the principal-agent problem. The principal is the employer who hires an agent, the employee to work for him. A principal-agent problem only comes up when information asymmetry exists. Two major problems of asymmetric information are adverse selection and moral hazard. Adverse selection is the issue of pitching the right type of agent. Moral hazard is the issue that the agent shirks after being hired. For example, if the British Secret Intelligence Service hires James Bond, it has to consider the adverse selection problem before the hire and the moral hazard problem after the hire. The problems the government would have to select the ideal candidate who is willing to kill on behalf of the country and for a government paycheck are the adverse selection problem. An adverse selection would be a person who is willing to kill for any other reason like a psychopath. The moral hazard problem is to make sure that the candidate does not change behaviour and is willing to work as hard as before the hire. James Bond for example has the incentive to exaggerate the difficulty of the assignment to extend his exotic life on the assignment. The government instead has no information if Bonds exotic requests are justified because Bond is the expert.
Ensino médio integrado e o ensino de língua portuguesa no IFTM
Authors: Moreira Henrique de Oliveira , Marques Welisson
Published: December 2023

A comunidade escolar, especificamente relativa ao Ensino Médio Integrado do Instituto Federal do Triângulo Mineiro, busca se mobilizar para ofertar aos jovens uma educação que seja realmente significativa. Por esse motivo, é preciso pensar na formação do cidadão para uma vida que contemple diversas variáveis como cultura, ciência, tecnologia; e não apenas para atender simplesmente as necessidades do mercado de trabalho. Faz-se necessária uma educação que garanta a todos igualdade de permanência na escola, e que também propicie o desenvolvimento pleno dos discentes em cada etapa de sua formação escolar, possibilitando que cada cidadão possa ser sujeito de suas ações e corresponsável nas relações das quais participa. Em vista disso, é necessário refletir e elaborar um currículo com a participação ativa de toda comunidade escolar, buscando o intercâmbio entre as conhecidas disciplinas (básicas e técnicas, no caso do Instituto Federal do Triângulo Mineiro). Nesse ponto, a Língua Portuguesa pode ser configurada como elo devido à sua abrangência e por facilitar a conexão entre os saberes que atualmente se apresentam fragmentados na perspectiva de uma formação plena.
O LUGAR IMPORTA: PREVALÊNCIA DE ALEITAMENTO MATERNO EXCLUSIVO DE ACORDO COM A REGIÃO, TIPOLOGIA MUNICIPAL E GRAU DE URBANIZAÇÃO NO BRASIL
Authors: Pereira Leonara Carla de Araújo , Magalhães Adriana Gomes , Barbosa Isabelle Ribeiro , Medeiros Anna Cecília Queiroz de
Published: December 2023

Objetivo: investigar a associação entre a prevalência de aleitamento materno exclusivo (AME), região, grau de urbanização e tipologia municipal. Métodos: Foram extraídos dados sobre a prevalência de AME por município brasileiro de 2019 a 2021 a partir do Sistema de Vigilância Alimentar e Nutricional. A prevalência de AME foi classificada em pobre/razoável e bom/muito bom. Os dados sobre região, tipologia municipal e grau de urbanização foram extraídos do Instituto Brasileiro de Geografia e Estatística. Para avaliação dos resultados foi utilizado o teste do Qui-quadrado e estimado o Odds Ratio. Resultados: amostra final obtida de 223.764 crianças distribuídas em 1603 municípios. A prevalência de AME no Brasil foi de 48,7%, considerada razoável. A região nordeste esteve associada a taxa de AME classificada como pobre/razoável (p<0,001). Houve associação entre alto grau de urbanização e taxa de AME do tipo bom/muito bom (p<0,026). Verificou-se também associação entre tipologia urbana e taxa de AME do tipo bom/muito bom (p<0,011). Conclusão: Os resultados apresentados revelam diferenças na prática de AME de acordo com a urbanidade e a região, o que demanda políticas e ações de saúde que considerem as particularidades dos territórios em que estão inseridas.
Desafios para a dicionarização de uma língua em obsolescência na Amazônia
Authors: Reis Jaqueline de Andrade , Ferreira Marília de Nazaré de Oliveria
Published: December 2023

As teorias tradicionais nas áreas de Lexicografia e Lexicologia foram desenvolvidas, em grande parte, a partir de trabalhos realizados com comunidades linguísticas saudáveis, com equipes de profissionais em que alguns desses eram falantes das línguas com as quais trabalhavam. Porém, com a expansão dos estudos descritivos de diferentes línguas, a criação de obras lexicográficas e lexicológicas tornou-se um desafio para os profissionais da área, uma vez que situações de obsolescência linguística, como é o caso apresentado neste artigo, impõem a necessidade de os aspectos práticos do trabalho serem realizados de forma alternativa, distinta daquela que está padronizada, sem que isso implique perda de qualidade na investigação realizada. O texto trata de uma experiência em que se verificam questões dessa ordem.
Um redemoinho no rio do devir: algumas notas sobre o conceito de origem em Walter Benjamin
Authors: Nunes Gabriel Galbiatti
Published: December 2023

Resumo: Este artigo tem o objetivo de apresentar algumas considerações a respeito do conceito de origem (Ursprung) para a concepção de história de Walter Benjamin, a partir de uma imagem, descrita pelo filósofo no texto ”Diário de 7 de agosto de 1931 até o dia de minha morte”. Com este artigo tenho dois objetivos: primeiramente, pretendo demonstrar como a categoria da origem é, para Benjamin, a raiz central que sustenta sua concepção de história; ademais, pretendo, a partir do Prefácio do livro Origem do drama barroco alemão, desenvolver algumas considerações que auxiliem a compreender o modo como é possível se realizar uma análise histórica fundada no conceito de origem, desenvolvendo alguns significados que o autor aponta para a categoria.
Palavras-chave: Walter Benjamin; Filosofia da História; Origem; Conceito de História; Epistemologia
A swirl in the river of becoming: some thoughts about Walter Benjamin’s concept of origin
Abstract: This article aims to present some considerations about the concept of origin (Ursprung) for Walter Benjamin's conception of history, based on an image, described by the philosopher in the text “Diary from August 7, 1931, to the day of my death”. With this article I intend to accomplish two things: first of all, I wish to demonstrate that the category of origin is, in Benjamin, the cornerstone upon which his conception of history is built; furthermore, I intend to search for tools that may help to understand the way in which a historical analysis is made possible when grounded upon the concept of origin, by focusing on specific meanings therein concerning that category.
Keywords: Walter Benjamin; Philosophy of History; Origin; Concept of History; Epistemology
 
Data de registro: 26/09/2022
Data de aceite: 30/08/2023
Enigmatic Cer Enigmatic Cervicofacial Actinomy vicofacial Actinomycosis P cosis Post Radiother ost Radiotherapy - A Case Report
Authors:   Oral Medicine Specialist, UWA Dental School, The University of Western Australia, Perth, Australia, phoonamanda@gmail.com, Phoon Nguyen Amanda
Published: December 2023

Although thought to be uncommon, it is believed that cervicofacial actinomycosis is underreported due to frequent misdiagnosis. It has been called the “most misdiagnosed disease by experienced clinicians”. A wide range of dental procedures or trauma, including tooth eruption, may precipitate actinomycosis by enabling microorganisms to penetrate the deeper tissue layers via an entry point. This infective disease is significant due to its potentially aggressive and locally destructive nature. This case describes a patient diagnosed with cervicofacial actinomycosis. Her history prior to this was significant for proliferative verrucous leukoplakia, and T4aN0M0 (AJCC 7th Edition) squamous cell carcinoma of the right hard palate for which she received surgery and post-operative radiotherapy. The mechanism of actinomycotic infection, its presentation, differential diagnosis, and management is discussed, with review of the relevant literature. This case highlights an unusual case of cervicofacial actinomycosis and demonstrates the complexities in reaching a definitive diagnosis in cases of osteomyelitis and osteoradionecrosis with significant bacterial burden.
Construction Project Risk at the Toll Road Construction Implementation Phase (Case Study: Solo – Jogja Toll Road Construction Project)
Authors: Susilowati Fajar , Tyagita Farah Claudias Nike , Miftahul Jannah Ria , Chrisnawati Yusfita
Published: December 2023

The Solo – Jogja Toll Road Development Project is a large-scale project with a large potential risk, especially at the project implementation stage. This research aims to find risks, obtain the level of risk by conducting a risk assessment, and recommend control measures against possible risks. The research method used in this study is HIRARC (Hazard Identification, Risk Assessment, and Risk Control). Purposive sampling was used to collect data from 30 respondents using a questionnaire based on certain criteria. The testing of this research instrument is in the form of validity and reliability tests using SPSS. In this research, 5 risk groups were identified during the implementation stage of the Solo - Jogja Toll Road Construction Project, including project risk, technical risk, natural risk, human risk, and occupational health and safety risk. The results of the analysis explained that the project has a risk range from low to high levels. The risk included in the high-level category is the risk of damage to roads around the project due to heavy equipment, such as dump trucks, project materials carriers, and trucks mixer. The risk can be minimized by creating a safe project access road, so that project activities do not cause further damage to the road.
The Influence of Local Wisdom in Construction Risk Assessment
Authors: Iriyanto Santje Magdalena , Sitorus Yannice Luma Marnala
Published: December 2023

One of the obstacles to construction work in Papua is delays in implementation due to obstruction byindigenous communities at the project site. Understanding the implementation of construction work in atraditional area, especially those related to local wisdom, is one of the risk knowledge which is the first step inrisk conceptualization and is the aim of this research. A qualitative approach, which will elaborate on socialand cultural meanings to explain one of the phenomena that occurs in the world of construction in Papua, anddescriptive methods, are used in analyzing research data. The characteristics of the traditional territory wherethe project location is located also influence the construction risk value of a project. Based on the topographiccharacteristics of the region, there are four large groups of Papuan indigenous people, so there are differencesin the construction risk values faced according to the socio-cultural characteristics of each traditionalcommunity. Urban areas have a high construction risk and rural areas have a lower risk. The risk value ofconstruction projects in Papua is also influenced by the type of construction project which will be related tothe required land pattern.
The influence of increased protein intake and L-carnitine supply on the outcomes of term newborns in intensive therapy
Authors: Anikin I. O. , Stryzhak L. S.
Published: December 2023

We studied the possibilities of increased protein and L-carnitine supplementation in full-term newborns with perinatal diseases to improve the results of intensive care.
Aim: to assess the impact of short-term increased protein consumption and L-carnitine supplementation by full-term newborns on the main indicators of treatment effectiveness in the intensive care unit.
Materials and methods. To check the impact of the proposed method of feeding newborns, the life indicators of 59 full-term children, who were randomly divided into two groups, were studied. The first group (n = 30) received standard nutrition with mother’s milk or formula, the second group (n = 29) received a food product fortified with a protein supplement and a subsidy of L-carnitine during hospital stay.
Results. Infants of both groups had statistically equivalent anthropometric characteristics at the beginning of the study. The proportions of infants of both sexes were within the 50 % percentile. Starting from the third week, caloric intake for the standard diet group (SG) and the enrichment group (FG), respectively, was 111.83 ± 7.19 kcal/kg/day, against 113.44 ± 5.61 kcal/kg/day, p = 0.0667. Per 1 g of protein, children in the FG group had amount of non-protein calories as 28.68 (27.50; 29.80) kcal/kg/day, compared to the indicator in the SG group of 42.37 (41.60; 38.00) kcal/kg/day, with U = 28.0000; p = 0.0001. Carnitine supplementation in the FG group led to an increase in the level of free carnitine in the last blood plasma samples, before the children were discharged home.
In general, the proposed nutrition strategy was accompanied by better indicators of the physical development of children, and a statistically probable faster recovery of body weight in the fortification group. Thus, the generalized indicator of body weight of children of the SG group was 3966.90 ± 439.08 g, compared to the FG group of 3554.62 ± 452.28 g, with p = 0.0033. In general, children who consumed more protein were transferred from the intensive care unit earlier – 12.00 (11.00; 16.00) days, against 10.00 (8.00; 12.00) days, with U = 235,00; p = 0.0024; previously discharged from the hospital – 26.50 (22.00; 31.00) days, against 21.00 (19.00; 27.00) days, with U = 267.00, p = 0.0109.
This strategy proved to be safe, as confirmed by normal levels of phenylalanine and urea at all stages of the examination of children.
Conclusions. Short-term increased protein consumption against the background of carnitine supplementation improves the results of physical development of newborns and indicators of hospitalization and intensive care unit stay. Larger studies and catamnestic observation of children are needed.
The relationship between fetuin-A level and the clinical features of patients with coronary artery disease associated with iron deficiency
Authors: Konovalova M. O. , Mykhailovska N. S.
Published: December 2023

The aim of the study: to assess the relationship between the level of fetuin-A and features of clinical hemogram, ferrokinetic parameters, vegetative and structural-functional changes of the myocardium in patients with coronary artery disease (CAD) associated with different stages of iron deficiency (ID).
Materials and methods. The study involved 90 patients with CAD: stable angina pectoris II–III FC (35 men and 55 women, age – 69 (61; 72)). All patients were divided into 4 clinical groups depending on the parameters of iron metabolism and hemogram: I (n = 16) – patients with absolute ID, II (n = 15) – with latent ID, III (n = 14) – with functional ID; IV (n = 45) – patients CAD without iron metabolism disorders. The physiological concentration of fetuin-A was determined in 15 conditionally healthy people. The results of echocardioscopy, Holter ECG monitoring and their relationship with the level of fetuin-A were analyzed.
Results. In patients with CAD associated with various stages of ID, there is a decrease in the concentration of fetuin-A in direct proportion to the degree of progression of sideropenia was established. It was established that there is a relationship between the level of fetuin-A and the concentration of ferritin and transferrin saturation for patients with absolute ID as well as the number of erythrocytes in patients with functional ID. It was established that there is a relationship between the level of fetuin-A and PWd (rs = -0.60, p < 0.05) for patients with absolute ID; for patients with latent ID – with the E/A ratio (rs = +0.66, p < 0.05). In patients with absolute ID and latent ID a number of correlations between fetuin-A level and heart rate variability indicators in active and passive periods was established. The presence of a low level of fetuin-A in patients with CAD and ID increased the risk of left ventricular hypertrophy by 1.5 times, left ventricular diastolic dysfunction by 1.6 times, autonomic dysfunction by 2.14 times in the active period and 1.95 times in the passive period.
Conclusions. In patients with CAD, there is a progressive decrease in the fetuin-A level depending on the degree of ID, which contributes to the deepening of disorders of iron metabolism and clinical hemogram, negatively affects the structural and functional state of the myocardium and heart rate variability, increases the risk of developing myocardial hypertrophy, left ventricular diastolic dysfunction and vegetative imbalance.
From agricultural practices to mining activities: The consequences of this paradigm shift for the food security in Guinea
Authors: Diallo Boubacar Sidi , Soumah Mamadouba Sayon
Published: December 2023

This study aims to analyse the effects that the mining activity exercises on agriculture and the livelihoods of local communities in the Republic of Guinea. Mining and agricultural activities are intertwined in such a way that the operation of one affects the other. Over the years, mining activities have been seen to negatively affect farming, livestock grazing and fisheries in the surrounding communities. Mining consists in the excavation of useful and economically valuable minerals from deposits in the earth. Despite its potential to generate a large amount of revenue, the mining sector is not adequately regulated, and as a consequence creates a ground for illegal mining activities. These activities, depending on the type of mining, have a spectrum of effects on agricultural activities including competition for land control and use, pollution of water bodies and exposure of crops and livestock to the harmful effects of heavy metals. The cumulative effects of these activities have modified the agricultural practices, disrupted landscapes, and negatively influence the availability of food crops in the areas where mining activities are carried out, which in turn threatens the food security of the region of Boké. This article also evaluates the impacts of mining on agricultural activities in the region, with a view of providing evidence for policymakers for taking necessary action and foster sustainable solutions.
Nabycie nieruchomości rolnej w drodze zasiedzenia po zmianie Kodeksu cywilnego i ustawy o kształtowaniu ustroju rolnego
Authors: Michałowski Rafał
Published: December 2023

Artykuł dotyczy skutków uchylenia art. 172 § 3 Kodeksu cywilnego, który stanowił, że nabywcą nieruchomości rolnej w drodze zasiedzenia mógł być wyłącznie rolnik indywidualny. Celem rozważań jest określenie, czy w związku z uchyleniem tego przepisu każdy podmiot prawa cywilnego może nabyć przez zasiedzenie nieruchomość rolną, czy nabycie takiej nieruchomości przez zasiedzenie jest objęte zakresem zastosowania art. 2a ustawy z dnia 11 kwietnia 2003 r. o kształtowaniu ustroju rolnego. W podsumowaniu autor stwierdza, że do nabycia własności nieruchomości rolnej w drodze zasiedzenia stosuje się art. 2a ustawy o kształtowaniu ustroju rolnego. Dlatego zasadniczo nieruchomość rolną w drodze zasiedzenia może nabyć rolnik indywidualny. Możliwe jest również zastosowanie niektórych wyjątków od tej zasady wskazanych w art. 2a ust. 3 tej ustawy. Wątpliwości rodzi stosowanie w odniesieniu do zasiedzenia zgody na nabycie nieruchomości rolnej przewidzianej w omawianej ustawie.
Organy koordynujące współpracę i kontakty w ramach urzędowych kontroli żywności – zagadnienia wybrane
Authors: Serlikowska Agnieszka
Published: December 2023

Celem rozważań jest zdefiniowanie pojęcia organów koordynujących współpracę i kontakty w ramach urzędowych kontroli żywności oraz udzielenie odpowiedzi na pytanie, czy polski ustawodawca zrealizował obowiązek ich wyznaczenia. Autorka, analizując sytuację w poszczególnych krajach UE, wskazuje na niejednolite podejście do realizacji tych obowiązków, występujące również w rodzimych regulacjach. W konkluzji zauważa, że polski ustawodawca zrealizował ten obowiązek jedynie częściowo, wprowadzając przepisy dotyczące wyznaczenia organu koordynującego współpracę i kontakty w sześciu z dziesięciu obszarów określonych unijnym rozporządzeniem. Konieczne jest zatem doprecyzowanie regulacji w pozostałych czterech obszarach oraz pomocniczo desygnowanie organu odpowiedzialnego za kontrole mające zastosowanie do zwierząt i towarów importowanych lub eksportowanych z Unii Europejskiej.
Evolución del concepto de evocación en la protección de las Denominaciones de Origen e Indicaciones Geográficas Protegidas en la jurisprudencia del Tribunal de Justicia de la Unión Europea
Authors: Sánchez Jaraba José Ramón
Published: December 2023

Las Denominaciones de Origen Protegidas y las Indicaciones Geográficas Protegidas constituyen las principales figuras de protección a nivel de la Unión Europea de los productos agroalimentarios de calidad vinculados a un origen geográfico determinado. Pese a estar integrados en dos cuerpos normativos diferentes, la Unión Europea pretende crear un marco regulador lo más unificado posible que dé una respuesta uniforme a estas figuras de calidad, aproximando ambos reglamentos. Con este propósito, el reciente Reglamento (UE) núm. 2117/2021, de 2 de diciembre de 2021 del Parlamento Europeo y del Consejo, modifica los Reglamentos 1151/2012 y 1308/2013 para, entre otras cuestiones, aproximar las definiciones de “denominación de origen” y de “indicación geográfica” contenidas en ambos bloques normativos. Ambas normativas protegen estas figuras, frente, entre otras acciones prohibidas, a cualquier uso indebido, imitación o evocación que de las mismas se pudiera realizar. Concretamente, el concepto de evocación ha sufrido una evolución interpretativa por parte del Tribunal de Justicia de la Unión Europea desde la sentencia más antigua, que data de marzo de 1999, hasta la más reciente, de septiembre de 2021. El objetivo de este trabajo es poner de manifiesto la evolución de este concepto para entender mejor su alcance e importancia.
Lab-grown Meat and the Proposed Italian Ban
Authors: Spoto Giuseppe
Published: December 2023

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