bluuebunny/crossref_metadata_2025 huggingface dataset:
ID: 1060 Organic-inorganic Biomaterials promote mesenchymal stem cell proliferation and differentiation for long-term cultivation
Authors: Yusoff Umul Hanim , Ebrahimi Shamsi
Published: September 2017

Background: A nifty propagating of mesenchymal stem cell (MSCs) diligence has germinated all over the world by innovative investigators. However, the clinical and basic research applications of MSC requires novel finding biomaterials interfacial interaction especially in sustainable the morphology, physiology, multipotent and phenotypically in long-term cultivation. A prominent of biomaterials benefit to MSCs culture has triggered the multitudinous field especially in regenerative medicine. In order to hinder the deprivation of MSCs in purity and potency, the alternative cell-substrate materials of MSCs culture is essentially to be discovered.

This has instigated the idea to encountered the method of screening libraries organic and inorganics biomaterials in bio-adhesively, free ethically, and sustainability to support the morphologically, physiologically, multi-potent and phenotypically of substrates coating cover slip.

 Methods: Libraries of inorganic biomaterials substrates have been collected from co-researcher to conduct the initial screening phase of 100 myriad fabrications of substrates whereas enumerated as a Graphene Oxide (GO), Hydroxyapatite (HAp), and Bioactive Glass (BAG) coated cover slip and discs also several organic biomaterials. Wharton’s Jelly derived Mesenchymal Stem Cells (WJMSCs) and Denuded Amnion Mesenchymal Stem Cells (AMMSCs) have been seeded on each substrate in the 48-well plate. Top four leading substrates have been selected for further cultivation until up to 5 passage (>P5) for long term screening known as scaling up phase. Several parameters such as cell attachment, cell viability, kinetic growth, cell-materials osteogenic and adipogenic differentiation and cell phenotype have been analyzed. Top one cell-material culture will go forward to further long-term cultivation up to Passage 10(>P10).

 Results: Morphologically and phenotypically demonstrated that GOy1WJMSC showed the significance result among others.
ID: 1061 An investigation on the deleterious effects of cryoablation on hepatocellular carcinoma
Authors: Cam Ha Che , Minh Le Duy , Tri Le Minh , Phuong Pham Thi Ngoc , Phuc Tran Huu
Published: September 2017

Vietnam is witnessing an elevated mortality rate of hepatocellular carcinoma (HCC) [1]. The early symptoms of this cancer are usually vague and not unique to liver disorders, thus presenting difficulties in diagnosis and treatment. Therapies like chemo- and radiotherapy can only prolong patients’ lives without possible cure [2]. At present, in addition to novel therapies, cryoablation has demonstrated its therapeutic effectiveness in certain countries [3-6]. However, this technique is still uncommon in Vietnam. With the aim of introducing cryoablation to HCC treatment, we have developed a piece of cryoprobe apparatus and investigated its deleterious effects at tissue levels and in vitro cell viability. Our results showed that the cryoprobe using liquid nitrogen reached -159.9oC within 15.4 seconds. While full deleterious effects were witnessed in mice within investigated freezing duration, the same effects were only seen in rabbits after 90 seconds of freezing. 60 and 45 seconds of freezing only caused cellular damage. Finally, human malignant cells were killed by two freeze -thaw cycles in 90 seconds and 9 minutes respectively.
ID: 1062 The chicken egg tumor model provides an attractive system for evaluating anticancer drugs
Authors: Vu Binh Thanh , Hayashi Joel , Tamanoi Fuyu
Published: September 2017

Among various tumor models, the chicken egg tumor model provides an attractive system for tumor characterization as well as for characterization of drugs and nanoparticles targeting the tumor. Xenograft tumors can be grown rapidly on a highly vascularized structure known as the chorioallantoic membrane (CAM). In this poster, we describe a method for growing tumors on the CAM membrane. Freshly fertilized chicken eggs are incubated in the rotary humidified incubator. On day 10 of the embryo development, the CAM is detached from the inner eggshell, a window is made in the shell to expose the CAM, a Teflon ring is place above the blood vessel, and cancer cells are grafted and placed inside the ring. Three days post inoculation, solid tumors are ~5mm in diameter and can easily be observed through the shell window. We have used green fluorescent ovarian cancer cells to follow tumor growth. H&E staining of the tumor established by transplanting human ovarian cancer cells showed that the tumor established in the chicken egg closely resembles tumors from ovarian cancer patients. Intravenous injection of doxorubicin led to a dramatic inhibition of tumor growth without affecting egg overall survival, as organs obtained after the doxorubicin treatment exhibited normal appearance. Our study shows that the CAM assay is a promising model to evaluate tumor targeting and bio-distribution of nanoparticles
ID: 1066 Effects of biotin supplementation on the in vitro maturation of oocytes and the development of parthenogenetic diploid porcine embryos
Authors: Tu Nguyen Ba , Thuy Bui Hong , Thuan Nguyen Van
Published: September 2017

In mammals, Biotin serves a coenzyme in the metabolism of glucose, amino acids, and fatty acids. Biotin deficiency causes decreased rates of cell proliferation, disfunction in germ cells and fetal development. This study was carried out to determine the influence of Biotin supplementation to invitro maturation medium on the development of porcine oocyte and embryos. Biotin (0.0, 1.0, 10.0, 100.0 mg/l, respectively) was added into the oocyte maturation medium, the quality of mature oocytes was evaluated after 42h culturing. The parthenogenetic diploid embryos were produced by using electro-activation system, the quality of embryos was noted at 1-4 cells stage. The results showed that, Biotin can enhance the formation of the first polar body at the concentration of 10 mg/l, it can also improve the activation efficiency of parthenogenetic diploid embryos at the preimplantation stage from 2-4 cells. Therefore, the supplementation of 10mg/l Biotin to the in-vitro maturation medium has a beneficial effect on the parthenogenetic diploid embryos development in the pig.
ID: 1068 Effect of caffeine supplementation during in vitro maturation on development of parthenogenetic embryos derived from aging oocytes
Authors: Van Nguyen Thi Thuy , Nghia Doanh Duc , Thuan Nguyen Van , Bui Hong Thuy
Published: September 2017

“Oocyte aging” refers to degradation of oocytes which is considered as consequence of long time nuclear transfer manipulation which leads to the reduced success rate of somatic nuclear transfer (SCNT). Caffeine, which has ability of maintenance of the maturation-promoting factor (MPF) from oocyte metaphase, is considered as an improvement factor of oocyte quality. However, the influence of caffeine in aged oocytes in which duration of oocyte development is still unknown. In this study, the supplementation of caffeine during in vitro maturation of porcine embryos (from metaphase I to metaphase II) was examined on the parthenogenesis models and evaluated its effect in aged oocyte quality. After reaching metaphase I stage (27 hours) of in vitro maturation (IVM), oocytes were continuously cultured with or without 5mM caffeine until metaphase II (42 hours), then induced aging in basic medium without hormone for 6 hours before parthenogenesis activation. Results indicated that the supplementation of caffeine at metaphase I to metaphase II during in vitro maturation had significantly improved the development of embryo to four-cell, eight-cell and importantly blastocyst stage. There was noticeably significant improvement in rate and quality of blastocyst of aging oocytes treated with caffeine compared to non-treated group (39.1% and 10.3%, respectively). Furthermore, caffeine treatment can reduce the fragmentation of aging oocyte. Hence, the interpretation of caffeine supplementation during metaphase I to metaphase II could improve the quality of embryo development and quality of blastocysts developed from aging oocytes (6 hours).
ID: 1069 Effect of Diutyryl-CAMP and follicle stimulating hormone on in vitro maturation of porcine oocyte
Authors: Van Nguyen Thi Thuy , Duy Pham Truong , Thuan Nguyen Van , Thuy Bui Hong
Published: September 2017

In this study, we examine the effects of dibutyryl cyclic adenosine monophosphate (dbcAMP) and follicle stimulating hormone (FSH) on the maturation of nucleus and cytoplasm of porcine oocytes after in vitro maturation. The oocytes-granulosa cell complexes (OCGs) were cultured in three different maturation media: basic, basic+dbcAMP, and basic+dbcAMP+FSH to investigate the cumulus expansion and maturation of the fully-grown oocytes. Treated mature oocytes underwent parthenogenetic activation to examine the quality of the mature oocytes via the development of embryos. The results showed that there was a higher rate of cumulus expansion and maturation between the combination of dbcAMP and FSH group (95.1% and 85.3%) compare with the none treatment or only dbcAMP treated group (40.8% and 47.7%; 44.9% and 42.9% respectively). The results in embryos development showed that mature oocyte cultured in dbcAMP and FSH group had a higher rate of the embryos developed to the 8-cell stage (49.2%) than in the none treated or only dbcAMP treated group (26.5% and 27.6%). These results confirmed that the combination of dbcAMP 1mM and FSH 0.01 IU/ml could increase the quality of the mature oocytes and improved the preimplantation development of parthenogenetic diploid embryos
ID:1073 Assessment of intravenous infused human adipose derived stem cells homing in diabetic mice
Authors: Truong Nhat Chau , Vu Ngoc Bich , Bui Anh Nguyen Tu , Nguyen Cong Le Thanh , Bui Anh Thi Van , Vu Anh Thi Van , Dang Loan Thi Tung , Phan Ngoc Kim
Published: September 2017

Currently, Adipose-derived Stem Cells (hASCs) therapy is being promoted applied research in the treatment of many diseases, especially autoimmune diseases such as systemic lupus erythematosus, rheumatoid arthritis and type 1 diabetes. However, profound mechanisms of this potential therapy have not been understood entirely. It is questioned that which tissues transplanted cells home to, and how long they survive there?

In this work, we evaluated the migration, and survival duration of GFP-expressed hASCs (hASC-GFPs) in normal and STZ-induced diabetic mice. A number of 106 hASC-GFPs were intravenous transplanted into the mice. After 1, 3, 5, 7 days, the presence of hASC-GFPs in various organs such as heart, lungs, kidneys, spleen, liver and pancreas was detected by Imaging technique (iBox® ExplorerTM Imaging Microscope System_IMS) and the percentage of these cells in the tissues of diabetic mice was evaluated by Flow cytometry (FCM).

The results showed that the transplanted cells could be identified by both IMS and FCM. By IMS, it was clear that hASC-GFPs homed to lung and heart most at day 1 and 3, respectively and the signals were decreased gradually in both tissues. These imaging results were similar in normal and diabetic mice. By FCM, we detected the signals of hASC-GFPs in all six diabetic organs at day 1, 3, 5, 7. The signals expressed highest at day 1 (liver, heart), day 3 (lungs, kidneys, spleen) or day 5 (pancreas) and all gradually decreased until day 7.

Our results demonstrated that although difficult hASCs could home to the pancreas of normal as well as diabetic mice, but we need more experiments to make further conclusions regards the mechanism of their immigration and behaviour in the recipients.
ID: 1081 Development and validation of surface electrocardiogram in the septal accessory pathway localization in typical Wolff-Parkinson-White syndrome
Authors: Chu Si Dung , Pham Khanh Quoc , Tran Dong Van
Published: September 2017

Objectives: This study was designed characteristics of surface electrocardiogram (ECG) for the localization of septal accessory pathway (AP) in the typical Wolff-Parkinson-White (WPW) syndrome to develop a new algorithm ECG for the septal AP localization, and to test the accuracy of the algorithm prospectively.

 Subject and Methods: We studied 106 patients, in 65 patients with typical WPW syndrome have a single anterograde with the localization of Aps identified by successful radiofrequency catheter ablation (RCFA) to develop a new ECG algorithm for the septal AP localization. Then this algorithm was tested propectively in 41 patients were compared with the location of AP’s successful ablation by RCFA (gold standard).

 Results: We found that the 12 lead ECG parameters in 65 patients with typical WPW syndrome such as the transition of the QRS complex, delta wave polarity in V1 lead, delta wave polarity in at least 2/3 inferior leads and morphology QRS was “QRS pattern’’ in inferior leads in diagnosis for the localization of septal APs with hight accuracy predicted from 83.3% to 100%, and for development of a new ECG algorithm. Then the following 41 patients were prospectively evaluated by the new derived algorithm for the septal pathways with high sensitivity and specificity from 84.6% to 100%.

 Conclusion: 12-lead ECG parameters in typical WPW syndrome closely related to the septal AP localization, in order to develop the new ECG algorithm by parameters as above; and can be used to a new septal ECG algorithm in predicted the location APs with high accuracy predicted
ID: 1082 An in-vitro study to diagnose and distinguish breast and lung cancers using the PCB technology based nanodosimeter
Authors: Venkatraman Pitchaikannu , Sureka C.S.
Published: September 2017

Generally, in the modern field of nanodosimetry, the Printed Circuit Board (PCB) technology based 3D positive ion detector has been identified as a device to detect cancers in lungs and breast region. In the nano environment, these cancer cells have been diagnosed by the exhalation of specific volatile organic compounds (VOCs) which serves as eminent source biomarkers for cancer diagnosis. Earlier studies reported that lungs emit various VOCs include Benzene, Ethylbenzene, Cyclohexane, methanol, ethanol, dodecane and tridecane, and the breast emit alkanes, alkenes, ketones, halogenated hydrocarbons, aldehydes, alcohols, esters, unsaturated hydrocarbons, terpenes, siloxanes, and aromates. By employing VOCs exhalation, the field of nanodosimetry aids as a direct evidence that the diagnosis of critical organs like lungs and breast cancer cells without harming the patients is possible. In our present out, we carried out in diagnosing and to distinguishing the cancer tissues of breast and lung using PCB technology based nanodosimeter.
Detached wheat leaf assay for assessing the sensitivity of Puccinia triticina races to fungicides
Authors: Turra Camila , Reis Erlei Melo , Barcellos Amarilis Labes
Published: September 2017

ABSTRACT In experiments conducted in a growth chamber and in laboratory, the preventive, curative and eradicative action of fungicides was assessed for the control of Puccinia triticina races MFT-MT and TFP-HT. The effect of fungicides tebuconazole (triazole) and azoxystrobin (strobilurin) was evaluated separately. Seedlings were inoculated with a suspension of 50 x 103 uredospores/mL distilled water added of 120 μL adjuvant (polyoxyethylene sorbitan monolaurate Tween 20 - Synth). Fungicides were applied 24 hours before inoculation (preventive control), 96 hours after inoculation (curative control) and ten days after inoculation (eradicative control), both in seedlings (in vivo) grown in pots and in leaf segments (in vitro) on Petri dishes. The effect of treatments based on the number of uredia/cm2 and the production of uredospores/uredium were tested in vivo and in vitro. When applied preventively, for both races, the two fungicides controlled 100% leaf rust, and when applied curatively, only azoxystrobin led to 100% control. The tested races remain sensitive to azoxystrobin but maintain the reduction in sensitivity to tebuconazole. Detached wheat leaf assay was efficient in assessing the sensitivity of P. triticina races to fungicides and leaves remained green for 18 days.
Influence of electrochemical treatment on a typical laterite
Authors: Ayodele Adekemi L. , Agbede Oluwole A.
Published: September 2017

The results of the undrained shear strength (Su) and stiffness (Vs) of electrochemically stabilised residual tropical laterite soil (RTLS) are presented. Calcium (Ca2+) and phosphate (PO43−) ions from calcium chloride and phosphoric acid, respectively, were injected individually and together into remoulded RTLS by applying 1 and 2 V/cm direct current electrical gradient for 5 d to facilitate cementation within the treated soil. Three different systems were employed using 1·0 M calcium chloride or 0·01 M sodium chloride as the anolyte and 1 M phosphoric acid or 0·01 M sodium chloride as the catholyte. Polarity reversal was also employed in some tests. The efficacy of the treatment was based on the soil Su and stiffness. The injection of Ca2+ led to a reduction in both the Su (90%) and stiffness (8%) of the treated RTLS. The injection of PO43− resulted in improvement in both the soil Su (151%) and stiffness (20%) of the treated RTLS. The study concluded that in stabilising the RTLS, injection of PO43− is effective whereas the injection of Ca2+ is not.
Estimating the benefits of joint occupation for street works in the UK
Authors: Moran Joshua , Eskandari Torbaghan Mehran , Burrow Michael P N
Published: September 2017

The UK’s local road infrastructure is subject to frequent openings to maintain and invest in buried infrastructure. Opening a road reduces its structural integrity, necessitates the implementation of traffic management and causes environmental pollution. These in turn can result in increased road use costs, adversely affect local business, cause social disbenefit, reduce road asset value and necessitate unplanned maintenance. There are therefore benefits to be gained from coordinating the openings of the highway in similar locations. Shared highway openings, however, are often not realised in practice for a number of reasons, including the lack of public accountability among infrastructure providers and the absence of appreciation for quantifying the benefits of joint occupation. To address this, this paper describes a novel rigorous procedure, based on multicriteria analysis, developed for Staffordshire County Council that evaluates the primary monetised and non-monetised economic, social, political and environmental benefits and costs associated with joint occupation and enables potential joint occupation schemes to be ranked. The use of the procedure is demonstrated by two joint occupation schemes in a rural and an urban area of Staffordshire. The work highlights the advantages of encouraging collaborative working among service providers to reduce costs and to increase asset life.
Indirect evaluation of the compressive strength of recycled aggregate concrete with high fly ash ratios
Authors: Kurda Rawaz , de Brito Jorge , Silvestre José D.
Published: September 2017

In this study, the compressive strengths of concrete mixes made with high incorporation of fly ash (FA) and recycled concrete aggregates (RCA), individually and jointly, with and without superplasticisers (SP), were evaluated by non-destructive ultrasonic pulse velocity (UPV) test. Three mix families (0, 30 and 60% FA) were produced and, for each of these three families, three incorporation levels (0, 30 and 60%) of fine RCA were used with 0% and 100% of coarse RCA, with and without SP. In this study, the effects of each of these materials on the UPV of concrete mixes were determined. Different equations are proposed to predict the compressive strength of concrete mixes by means of the non-destructive UPV, according to their mix composition. Moreover, in cases where the FA content is known, as the oven-dried density of concrete can be easily determined, a simplified expression is proposed to estimate the compressive strength of concrete mixes according to their density and FA ratio (in terms of cement mass), regardless of the type and content of aggregates and content of the admixture, within the limits tested in this research.
Luminescence properties of tricellulose acetate composites emitting blue light
Authors: Peng Di , Huang Mengjun , Sun Xiangwei , Liu Xiang , Liu Renlong
Published: September 2017

A series of dinuclear complexes with molar ratios of cerium to lanthanum of 1:0, 1:1, 1:2, 1:4, 1:7, 1:9 and 0:1 was synthesized using 5-sulfosalicylic acid (SSA) as the first ligand and 1,10-phenanthroline (Phen) as the second ligand, recorded as Ce1−x La x (SSA)3Phen (x = 0, 0·5, 0·67, 0·8, 0·875, 0·9, 1), and the complexes were blended with tricellulose acetate (TCA) to obtain luminescent polymer materials. The compositions and structures of the rare earth complexes were determined through elemental analysis, energy-dispersive X-ray analysis, infrared spectroscopy and thermogravimetric analysis. Under the optimum excitation wavelengths, all dinuclear complexes emitting blue light displayed the characteristic emission of the cerium (Ce3+) ion. The fluorescence spectra showed that the 85:15 TCA/Ce0·2La0·8(SSA)3Phen composite showed the strongest fluorescence among all composites and the quantum efficiency was calculated as 30·6%. The introduction of the lanthanum (La3+) ion into the cerium ion complex can effectively reinforce the luminescence intensity of the complex and be favorable for retaining the excellent fluorescence in the TCA matrix. The 85:15 TCA/Ce0·2La0·8(SSA)3Phen composite possesses fine luminescence properties and thermal stability for potential usage as a blue fluorescent material.
Control of pile movements induced by tunnelling using micropiles
Authors: Sohaei Houman , Namazi Eshagh , Marto Aminaton
Published: September 2017

The effect of installing micropiles between the existing piles and the tunnel is not well understood. This paper discusses the effectiveness of micropiles as a means to control tunnelling-induced ground movement and movements of an existing pile, located at a distance of one times the tunnel diameter from the tunnel axis. Laboratory physical model tests had been conducted in dry sand of 50% relative density using a row of 3·7 mm dia. micropiles with two different lengths (110 and 145 mm), embedded in between the tunnel (overburden ratio of 3) and the existing pile at four different locations. During the tests, settlement, the bending moment and axial force of the existing pile have been monitored. The results show that the micropiles reduced by more than 85 and 75% of the piles’ lateral and axial movements, respectively. Within the limitation of the study, it has been concluded that the most suitable length and location of the micropiles are 145 mm (tip of the micropiles is closest to the tunnel crown), located exactly in the middle between the tunnel axis and the pile. It is based on the reduction observed on the vertical and lateral movements of the pile as well as in the bending moment, and the axial force.
Editorial
Authors: De Gloria Alessandro
Published: September 2017

The present IJSG issue hosts a guest section dedicated to selected papers from the Games and Learning Alliance Conference (Gala Conf - conf.seriousgamessociety.org), that was held in Utrecht, The Netherlands, in December 2016. The guest editorial processed has been managed by Rosa Bottino, of the Italian National Research Council, Institute for Educational Technologies, and by Johan Jeuring, of the University of Utrecht, who acted as conference chair [1].
Domesticating organ transplant
Authors: Clainche-Piel Marie Le
Published: September 2017

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‘White man’s disease’
Authors: Gilley Brian J. , Pfeiffer Elizabeth J.
Published: September 2017

Through critical reflection on the conspiracy theories told about the origins of HIV by American Indians, we learned that many community members refused the universalized aspects of AIDS prevention, education, and intervention. We found that standard HIV/AIDS-related prevention and treatment programs tend to universalize experiences with and responses to the AIDS epidemic and ignore – or push to the margin – alternative framings and understandings of this disease. Inspired by American Indians’ refusal to synthesize (in the Hegelian dialectical sense) their own experience into national and international AIDS knowledges, in this article we seek to engage with such marginal understandings, as well as their interactions with universal, individual, and community notions of care, AIDS, and health causality. The use of non-standard theories of the origins of AIDS by American Indians, we argue, disrupts the logic that attempts to universalize AIDS and community experiences. By making AIDS a ‘White Man’s disease’, Natives bring the epidemic in line with a history of social and health neglect by the settler state, and refuse to collapse their own, marginalized experiences and understandings of HIV/AIDS into dominant knowledges of the disease.
‘They overworked us’
Authors: Park Sung-Joon
Published: September 2017

In this article, I describe the institutional humiliation experienced by volunteer nurses in Sierra Leone following the end of the Ebola epidemic. They had been promised formal employment with the Ministry of Health and Sanitation after working in the Ebola treatment units in the country, but were dismissed from the hospitals where they were volunteering and felt humiliated. I suggest that this maltreatment of volunteer nurses cannot be grasped through the existing categories and parameters used by global health policies nor through conventional moral theories that inform our understandings of global health. Instead, we need to attend to the harm inflicted upon the volunteer nurses’ sense of self-respect through institutionalized forms of subordination and misrecognition. Drawing on philosophical and anthropological works on recognition, I argue that we should pay attention to moral emotions as distinct objects of study to grasp how those who are humiliated register and validate the maltreatment they have undergone.
Epic measures
Authors: Flood David , Chary Anita
Published: September 2017

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Who can stop the rot?
Authors: Faull Andrew
Published: September 2017

It is fitting that the first article in this issue of South African Crime Quarterly (SACQ) speaks to the South African Police Service’s tackling of commercial crime. It is increasingly clear that corporate–political collusion poses a serious threat to South Africa’s democratic gains. In recent months journalists have started to pick through a trove of emails released in June, known as the #GuptaLeaks. In the process they have connected the dots between tens of thousands of exchanges among the notorious Gupta business family, management of parastatals, governmentministers and allies of President Jacob Zuma, including his son Duduzane. The emails paint a terrifying picture of state capture and abuse.
Motivation and Self-Regulated Learning: A Multivariate Multilevel Analysis
Authors: Ahmed Wondimu
Published: September 2017

This study investigated the relationship between motivation and self-regulated learning (SRL) in a nationally representative sample of 5245, 15-year-old students in the USA. A multivariate multilevel analysis was conducted to examine the role of three motivational variables (self-efficacy, intrinsic value & instrumental value) in predicting three SRL strategies (memorization, elaboration & control). The results showed that compared to self-efficacy, intrinsic value and instrumental value of math were stronger predictors of memorization, elaboration and control strategies. None of the motivational variables had a stronger effect on one strategy than the other. The findings suggest that the development of self-regulatory skills in math can be greatly enhanced by helping students develop positive value of and realistic expectancy for success in math.
The Personality of a “Good Test Taker”: Self-Control and Mindfulness Predict Good Time-Management When Taking Exams.
Authors: Osgood Jeffrey , McNally Olivia , Talerico Grace
Published: September 2017

Much prior research has linked trait self-control and trait mindfulness with improved performance on overall academic metrics such as GPA. The present research expands on this literature by linking self-control, mindfulness, and closely related personality constructs to differences in the way students manage their time while taking exams. Students at two large public universities (total n = 362) completed scale measures of self-control, mindfulness, and their use of time when taking timed examinations. The results suggest that trait self-control (r = .174) and trait mindfulness (r = .311) are statistically significant predictors of effective time management while taking timed exams.
Management of Anger with Anger Reversal Technique among School Going Adolescents
Authors: Kumar Sella
Published: September 2017

An experimental investigation was attempted to examine the effectiveness of Anger Reversal Technique to manage anger among adolescent school students. One group pretest post test experimental design was adopted. Speilberger’s State Anger Scale was administered to assess the level of anger. A random sample of 52 male and 48 female adolescents were drawn from a selected higher secondary school located in Gondar Town, Ethiopia. Selected participants were randomly assigned to experimental and control groups. Anger reversal technique was administered for a period of 45 minutes/day for 45 consecutive days. A post test was conducted to ascertain the efficacy of anger reversal technique. Repeated measures ANOVA was worked out with SPSS 17 version. The result revealed that there is a significant decrease in the level of anger after anger reversal technique among adolescent students. Therefore, this intervention technique is effective in managing anger it can be adopted and employed to control anger among school students.
Moral Maturity Levels of Imam Hatip High School Students: The Case of Ortakoy District
Authors: Güven Naciye
Published: September 2017

The aim of this research is to determine the moral maturity levels of the Imam Hatip High School students. It is also to analyze whether the level of moral maturity differs according to gender, class level and place they stayed. The study was carried out on 220 students of the İmam Hatip High School in the district of Ortakoy in Aksaray in the academic year 2016-2017. The study is a descriptive screening model. The '' Moral Maturity Scale '' developed by Şengün and Kaya (2007) and the '' personal information form '' created by the researcher were used as data collection tools in the study. Scale is a likert type measure of 66 items. The reliability of the scale is 0.89. As a result of the study, it was determined that 55 % of the Imam Hatip High School students had a moral maturity level above the average. In addition, gender, class level, and place they stayed did not make a significant difference on the level of moral maturity.
WILMS TUMOR IN ADULTS: CASE REPORT AND REVIEW OF THE LITERATURE
Authors: Bereza Bruno Rafael Kunz , Foiato Maneti Tariane Friedrich , Ferreira Cathcart Vitor Arce , Leal do Rosário Raimundo Romilton , Nunes Paula , Luz Murilo de Almeida
Published: September 2017

Wilms Tumor (WT) is an extremely rare neoplasia in adults. It represents 95% and 1% of all renal tumors, in adults and children respectively. Clinical symptoms are also distinct between adults and children. In adults, symptoms are usually abdominal pain and hematuria, on the other hand, pediatric patients frequently present with an asymptomatic abdominal mass. The recommended treatment for WT in adults follows protocols established for pediatric patients. Currently, the 5-year overall survival rate for adults with WT is of approximately 90%. The adoption of multimodal therapy systematized, and proposed by current protocols, allowed the results to become much more robust, with a significant improvement from less than 30% to 90%. However, recent reviews suggest a worse outcome for adults when compared to children, even when submitted to the same treatment regimen, and comparable according to histology and tumor stage.We present a case of a 26 years-old male patient, who underwent surgery to treat a solid renal mass. Pathological report demonstrated a Wilms tumor. The patiente also received adjuvant chemotherapy with dactinomycin and vincristine. After 12 months follow-up, patient has no evidence of disease.
Seroprevalence of Human Herpesvirus Type 2 in a Reference Center for Pregnant Women in Rio de Janeiro, Brazil
Authors: Lima Lyana , Padalecki Guilherme , Castro Carlos , Cordeiro Jânio , De Paula Vanessa
Published: September 2017

Introduction: Pregnant women stand as an relevant group for research about Human Herpesvirus (HHV-2) infection owing to the risk of mother-to-child transmission. Methods: Women attending in a prenatal care center were tested for HHV-2 IgM and IgG by ELISA. Quantitative PCR test was the chosen method to ascertain viremia. Results: The seroprevalence of IgG and IgM anti-HHV-2 was 20.6% and 2.2% respectively. HHV-2   viremia was found in one pregnant  woman with HHV-2 IgM, leading to the assumption of primary infection.  Conclusion: The significantly high prevalence of HHV-2 found and the ascertainment of primary infection in a pregnant woman underline the need for constant HHV-2 follow-up and diagnosis in order to avoid sexual transmission.
Assessment of Hepatitis B and Hepatitis C Knowledge and Attitudes in a Sample of Health Care Workers from Southeast Brazil
Authors: Villar Livia Melo , Silva Glaucia Sarmento , De Paula Vanessa Salete
Published: September 2017

This study aims to assess the knowledge and attitudes about hepatitis B and C viruses (HBV and HCV) in health care workers (HCW). A total of 266 HCW from Rio de Janeiro State (Southeast Brazil) answered an instrument containing 17 questions to study viral hepatitis knowledge and 12 statements regarding attitude and behavior about HBV and HCV. Mean HCWs’ knowledge level was considered satisfactory (mean knowledge score was 12.21 ± 3.36), but almost half of HCW presented low knowledge level (score lower than 12.21). High knowledge level was observed in individuals with previous HBV vaccination. Mean attitude score was 39.06±10.47 showing high level of positive attitudes, particularly among dentists and professionals who had previous needle stick injury. In conclusion, almost half of HCW had low level of knowledge about HBV and HCV and some gaps were identified showing the importance of continuous viral hepatitis education to HCW in this setting.
Tissular Distribution of Argentinean Strains of Bovine Herpesvirus Type 4 (BoHV-4) in Experimentally-Infected Calves
Authors: Morán Pedro Edgardo , Pérez Sandra Elizabet , García Jorge Pablo , Castro Alejandra Nelly Cristina , Spetter Lucas Maximiliano , Odeón Anselmo Carlos , Verna Andrea Elizabet
Published: September 2017

Although bovine herpesvirus type 4 (BoHV-4) is primarily associated with reproductive disorders of cattle, it can produce a variety of clinical signs. To determine the distribution, the presence and type of microscopic lesions caused by BoHV-4 strains of different genotypes an in vivo model, calves were infected with three phylogenetically different Argentinean BoHV-4 strains. Samples from nasal and ocular secretions, peripheral blood leukocytes, tissues and serum were analyzed. BoHV-4 was isolated from nasal and ocular secretions at 7 and 14 days post-inoculation (dpi). Viral DNA was detected by nested PCR in peripheral blood leukocytes at 14 and 21 dpi for two out of three strains and in tissues, such as nervous system, trachea, pulmonary and retropharyngeal lymph nodes, spleen and kidney, at 21 dpi. Antibody levels detected by viral seroneutralization test were mostly low and varied widely for the different strains. The tissue distribution of the BoHV-4 strains and the variations observed in the levels of neutralizing anti-bodies indicate that certain differences can be established among the patterns of biological behavior of each strain. This is an initial step to get insight into the biological characteristics of Argentinean BoHV-4 isolates. However, further evaluation involving a higher number of inoculated animals will be required to be conclusive on this aspect.
Investigation of Ehrlichia spp., Anaplasma spp. and Rickettsia spp. in ectoparasites collected from domestic animals, Rio de Janeiro State, Brazil
Authors: Da Silva Thayssa Keren , Blanco Carolina Moreira , Ogrzewalska Maria , Barbosa de Souza Mariana , Dias Barreira Jairo , Santos Moreira Namir , Monteiro de Mello Mares-Guia Maria Angelica , S. de Lemos Elba Regina
Published: September 2017

The aim of this study was to determine the occurrence of emerging arthropod-borne pathogens Anaplasma, Ehrlichia and Rickettsia infection in ticks (Acari: Ixodidae) and fleas (Insecta: Siphonaptera) collected from dogs and horses within municipality of Itaboraí, Rio de Janeiro State, Southern Brazil. Samples from 280 ticks and two fleas were subjected to family or/and genus specific PCR for Anaplasmataceae, Ehrlichia and Rickettsia, followed by DNA sequencing to ensure pathogen identity. In ticks Rhipicephalus sanguineus collected from dogs the DNA of Anaplasma platys and Ehrlichia canis was detected in 6.8% and 2.2% samples respectively. In two R. sanguineus confection with two pathogens was observed. In Dermacentor nitens ticks, collected from horses Francisella-like endosymbiont was found in 42.8% samples. DNA of Rickettsia felis and Wolbachia pi-petens was detected in fleas Ctenocephalides canis fleas. No DNA of Rickettsia was found in tested ticks. The findings contribute to our knowledge of tick-borne bacteria, ticks and endosymbionts distribution in Brazil.
Genocide Discourses: American and Russian Strategic Narratives of Conflict in Iraq and Ukraine
Authors: Irvin-Erickson Douglas
Published: September 2017

This paper presents the concept of “genocide discourses”, defined as a type of strategic narrative that shapes the way individuals and groups position themselves and others and act, playing a critical role in the production of violence and efforts to reduce it. Genocide discourses tend to present genocide as fundamentally a-political, and hold that genocidal systems are dislodged only when they are swept away through external violence. Secondly, genocide discourses are built on an assumption that the victims of genocide are necessarily moral innocents, not parties in conflict. These two factors make genocide discourses highly effective in conferring moral capital upon certain actors in a conflict. The two principles converge to produce strategic narratives that direct political and military actions in certain ways in the context of contentious conflicts and political violence, motivating humanitarian responses in defense of certain groups, or sustaining popular support for foreign wars. The paper illustrates the argument by examining two case studies between 2014 and 2017: the debates in the United States over Islamic State genocides, and the conflict between Ukraine and Russia.
Strategic Narratives and Alliances: The Cases of Intervention in Libya (2011) and Economic Sanctions against Russia (2014)
Authors: Roselle Laura
Published: September 2017

Scholars of international communication recognize that strategic narratives are important for policymaking (Miskimmon, O’Loughlin, & Roselle, 2013) and scholars studying alliances suggest that communication is central to the formation and maintenance of alliances (Weitsman, 2010). This essay addresses how strategic narratives affect US alliance behavior—and hence international order—in two specific ways. First, alliance behavior can be affected by other allies’ narratives as demonstrated in the case of military intervention in Libya in 2011. Here the evidence suggests that the UK and France were able to use strategic narratives to influence the decision of the US to agree to military intervention in Libya by using narratives that could evoke a fear of abandonment. Second, alliance cohesion can be affected by narrative contestation by non-allies as demonstrated in the case of the Ukrainian crisis in 2014. Russia has used strategic narratives in a new media environment in an attempt to elicit a fear of entrapment to counter the US attempts to coordinate alliance support for economic sanctions. In both cases, distinguishing between system, identity, and policy narratives give us a deeper understanding of narrative contestation today. This analysis adds to our understanding of the factors that affect alliances set within a new media environment characterized by a proliferation of sources and outlets and thus a more horizontal structure of information exchange.
Zur Quantfizierung und Analyse der Nichtlinearität von Regressionsmodellen
Authors: Sedlacek Günther
Published: September 2017

Bei nichtlinearen Regressionsmodellen treffen im endlichen Stichprobenfall eine Reihe von statistischen Aussagen nicht zu, die für das lineare Regressionsmodell gelten. So ist die (iterativ berechnete) Kleinste-Quadrate-Summen-Schätzfunktion (KQS-Schätzfunktion) imnichtlinearen Fall nicht effizient, wenn sie auch unter gewissen Voraussetzungen asymptotisch effizient ist. Für nichtlineare Regressionsmodelle werden daher statistische Aussagen gerne mit Hilfe der asymptotischen Theorie getroffen. Zeigt das Regressionsmodell aber ausgeprägt nichtlineares Verhalten, so führen so erhaltene Aussagen zu falschen Ergebnissen. Nichtlinearitätsmaße wie die von Bates and Watts (1980) geben Aufschluß darüber, wie ausgeprägt die Nichtlinearität eines Regressions-modells ist. Passende Parametertransformationen sowie die Verwendung eines geeigneten Versuchsplans sind Möglichkeiten, die Nichtlinearität zu reduzieren, sodaß mit Hilfe von linearen Approximationen getroffene Aussagen zu validen Ergebnissen führen. Eine Fallstudie illustriert die Auswirkungen der Wahl der Versuchspunkte auf die Nichtlinearität eines Modells; die Verwendung eines geeigneten Versuchsplans kann zu einerdeutlichen Reduzierung der Nichtlinearität führen.
Bayesian Smoothing of Lung Cancer Data in Tirol, Salzburg and Vorarlberg
Authors: Koboltschnig Rose-Gerd
Published: September 2017

Due to the high variability ofML-estimates of relative risk in low population areas incidence ratios have to be smoothed before mapping. We fit a Bayesian hierarchical model where the posterior distribution of relative risks is simulated via a Markov Chain Monte Carlo technique.
Standard Operating Procedures - Schnittstellen zur Biometrie aus der Sicht des Sponsors
Authors: Pölz Werner , Schimetta Wolfgang , Pölz Gabriele
Published: September 2017

Verfahrensanleitungen (SOPs) dienen zur Standardisierung von Vorgangsweisen. Indem sie ständig aktualisiert werden, tragen sie wesentlich zur Qualitätsoptimierung bei. In klinischen Studien sollten SOPs von allen beteiligten Parteien (Prüfarzt, Sponsor, Biometriker) verwendet werden. Der Prüfarzt (Prüfer) gewährleistet damit u.a. die Wahrung der Sicherheit und der Rechte der Studienteilnehmer (Versuchspersonen), die qualitativ einwandfreie und möglichst vollständige Datenerhebung und -dokumentation sowie die Einhaltung der Rechtsnormen. Der Sponsor verwendet SOPs für die Normierung von Planungs- und (Qualitäts-)Überwachungsaktivitäten, für Melde-, Versicherungs- und Dokumentationspflichten sowie ebenfalls für die Einhaltung der Rechtsnormen. Ein bewährtes Modell stellt die Positionierung des Biometrikers als dritte autonome Partei neben dem Prüfer und dem Sponsor dar. Dementsprechend sind die Verantwortlichkeitsbereiche klar abzugrenzen und Schnittstellen in Form von Anforderungenan die jeweilige andere Partei (bezüglich Qualifikation, Ressourcen, internes Qualitätsmanagement etc.) zu definieren.
Metadata Management in Official Statistics–An IT-based Methodology Approach
Authors: Froeschl Karl A.
Published: September 2017

There is a considerable impact of evolving information technology (IT) on Official Statistics. Coping with both risks and potentials of this development, Official Statistics is in serious need to address questions of keeping the statistical system functional and responsive to increasing requirements whilst facing rather tight economic conditions. At any rate, it can be anticipated that new approaches to information management will play a prominentrole in the re-engineering of statistical infrastructures; in particular, metadata management will turn out as key factor in this indispensable renewal of statistical data production and dissemination systems. After tracing emergent developments back to their interwoven origins in both statistics and IT hemispheres, this paper singles out the dominant issues and components of next-generation metadata-based IT frameworks taking shape in the domain of Official Statistics, and proposes some framework design principles.
Geographische Informationssysteme (GIS) des Österreichischen Statistischen Zentralamtes (ÖSTAT) und der Europäischen Union
Authors: Desoye Helmut
Published: September 2017

Im ÖSTAT wird das Geographische Informationssystem STATGIS entwickelt, in der EU besteht seit 1992 das GIS der Europäischen Kommission (GISCO). STATGIS wird es in den Richtmaßstäben 1 : 500 000, 1 : 5 000 und 1 : 50 000 geben. Kernstück ist das STATGIS1 : 5 000, das auf Adreß- bzw. Gebäudekoordinaten basiert und statistische Auswertungen für beliebige räumliche Gebilde ermöglicht, vorbehaltlich der Datenschutz bleibt gewahrt. Für die anderen Richtmaßstäbe sollen u.a. Standardprodukte angeboten werden. GISCO enthält eine große Menge topographischer und thematischer Informationen und wird ständig verbessert. Gesamtziel ist die Schaffung eines Europäischen Datenbanksystems für Geoinformation in mehreren Stufen, wobei auch ein Verbund mit nationalen undregionalen Informationssystemen hergestellt werden soll.
Nachdenkliches zur Statistik aus Anlaß eines neuen Gesetzes
Authors: Klein Kurt
Published: September 2017

Botschaften aus der Vergangenheit unserer Profession lassen uns manchen Gedanken des neuen Gesetzes als Elemente einer zukünftigen ”Statistik-Kultur“ verstehen. Die offenen Fragen ringsum lösen sich dadurch nicht einfach auf.Der Autor, nach 35 Jahren Tätigkeit im Statistischen Zentralamt (davon 20 Jahre als Abteilungsleiter und die letzten 5 als Vizepräsident) vor dem Ruhestand, sieht dennoch gute Gründe, sich mit diesem Gesetz entschlossen auf den Weg zu machen.
Bundesstatistikgesetz 2000 – Vorgaben, Motive, Ziele
Authors: Kutzenberger Ewald , Richter Josef
Published: September 2017

Die Bestimmungen des Bundesstatistikgesetzes 2000 werden vor dem Hintergrund der vier zentralen politischen Ziele gesehen, denen das Gesetz verpflichtet ist: Erstens der Reorientierung des statistischen Systems, um die Unabhängigkeit der Statistik zu stärken und ihre Funktion als Öffentliches Gut zu sichern. Zweitens die Voraussetzungen für eine deutliche Verbesserung der Produktionsbedingungen für die amtliche Statistikzu schaffen. Drittens die Belastung von Bürgern und Betrieben merkbar zu reduzieren und viertens den Bedingungen des neuen Datenschutzrechts zu genügen. Wenn Defizite im Blick auf die Vision eines idealen statistischen Systems verbleiben, so sind sie das Resultat von Zielkonflikten, aber auch dadurch bedingt, daß eine Verwirklichung tiefe Eingriffe in bestehendes Recht notwendig gemacht hätte.Die Umwandlung des Österreichischen Statistischen Zentralamts in eine Anstaltöffentlichen Rechts dient der besseren Umsetzbarkeit der inhaltlichen Vorgaben des Gesetzes. Das Gesetz räumt der Leitung der Anstalt mehr Flexibilität und Planbarkeit bei größerer Verantwortung für die Ergebnisse ein. Mit der Anstalt ”Statistik Österreich“ wurden die Weichen zur Schaffung eines echten Kompetenzzentrums für qualitativ hochwertige, unabhängige und aktuelle statistische Daten gestellt. Die Bundesstatistik wird in die Lage versetzt, mit dem Bürger einen Pakt zu schließen, aus dem beide Partner Gewinnziehen.