bluuebunny/crossref_metadata_2025 huggingface dataset:
The Role of Open Standard Electronic Health Record in Medical Data Mining
Authors: Khanal Rajesh
Published: October 2018

Electronic Health Record (EHR) has received significant attention of all the health service provider in the world. EHR contains electronic information of all the patient information such as demographics, medical history, family medical history, lab tests and results, and prescribed drug. There is not any consistency in type of the EHR software implemented by the hosting organization. So, the EHR is currently vendor dependent and is not transferrable to another health service provider. The open standard electronic health record makes it public available to both vendor and patient. It can further aid in creating a universal EHR database for medical data mining. Mining the EHR helps in developing the best standard of care and clinical practice. The following paper proposes a universal EHR database and medical data mining. The benefits and challenges of implementing a database system is also discussed in the paper. The following paper will also analyze the different application areas of the EHR data mining.
TORTOR BATAK TOBA SEBAGAI SUMBER PENCIPTAAN GAMBAR ILUSTRASI DENGAN APLIKASI PHOTOSHOP CS3
Authors: Sidabutar Yohanda , Mangatas Mangatas
Published: October 2018

ABSTRAKPenciptaan ini bertujuan untuk menghasilkan karya gambar ilustrasi tortor Batak Toba, serta mendeskripsikan langkah-langkah penciptaan yang dilaksanakan. Skripsi ini menguraikan tentang pembuatan karya yang diciptakan dalam tugas akhir. Proses penciptaan karya akan dijelaskan mulai dari proses awal sampai dengan selesai. Hasil karya yang dicapai dari proses penciptaan ini berjumlah 10 karya dengan gerak tortor  yang berbeda-beda dengan berukuran A3. Dalam penciptaan ini mulai dari karya 1 hingga 10 dapat terilustrasikan  urutan gerak Tortor Sipitu Sawan hingga selesai. Pada penciptaan karya ini mulai dari karya 1 hingga 10 menggunakan prinsip desain center of point dimana penari merupakan pusat perhatiaannya. Dalam penciptaan karya ini, penulis menggunakan media komputer yang sebelumnya diawali dengan pembuatan sketsa secara manual menggunakan pensil, kemudian sketsa tersebut di scan dan dilanjutkan dengan teknik digital menggunakan media komputer yang memiliki Software Adobe Photoshop Cs3. Dalam Software ini menggunakan system layer untuk memudahkan proses editing dan memiliki fitur pewarnaan dan efek yang relative lengkap dan bervariasi sehingga penulis lebih leluasa menggunakan fitur-fitur yang tersedia dalam berkarya.           Kata Kunci: Penciptaan, Ilustrasi, Tortor Sipitu Sawan, Photoshop Cs3
ANALISIS SELF CONFIDENCE TERHADAP KEMAMPUAN PEMECAHAN MASALAH MATEMATIS SISWA SMK PADA MATERI BARISAN DAN DERET
Authors: Ramdan Zenal Muh , Veralita Liana , Rohaeti Euis Eti , Purwasih Ratni
Published: October 2018

This study aims to determine the relationship between self confidence on the mathematical problem-solving abilities of students of SMK on the sequence and series material. The method in this research is descriptive qualitative. The place of research conducted at SMK Al-Ibrohimiyah Cianjur academic year 2018/2019 class XII Administration Offices with the number of 17 students. The instruments in this research are self confidence scale questionnaire and math solving ability test. Analysis of data used in this study using SPSS 21.00 with product moment analysis to measure the relationship of self confidence to the ability of problem solving mathematically. Based on the calculation, the result of data analysis shows that there is a correlation coefficient (r) of 0.784 with p = 0,000 (p <0.01) which means there is a significant positive relationship between self confidence on the ability of problem solving mathematically. This means that self confidence covering the aspects that exist in it can be used as a predictor to measure the ability of problem solving mathematically, the higher the self confidence of students, the students have good problem solving skills, otherwise the lower the students' self confidence, the students has a poor problem solving ability.
PENGARUH MODEL PEMBELAJARAN TANDUR TERHADAP PENINGKATAN KEMAMPUAN PEMAHAMAN KONSEP DAN PENALARAN MATEMATIS PESERTA DIDIK
Authors: Astuti Titin Puji , Masykur Rubhan , Pratiwi Dona Dinda
Published: October 2018

The aims of this research to gain the result of effect TANDUR model to mathematical concept understanding and student’s mathematical reasoning. This research was quasi experiment with pretest-postest control group design. The population in this research was students of seventh grade SMP N 2 Natar academic year 2017/2018. The sampling technique used random sampling technique and divided onto two groups, experiment group and control group. The results of this research were: 1) there was influence of TANDUR learning model to mathematical concept understanding. 2) there were influence of TANDUR learning model to mathematical reasoning. 3) TANDUR model learning can affect simultaneously of mathematical concept understanding and mathematical reasoning.
The social characteristics of the nobility in Stavropol province in the late 19th – early 20th centuries
Authors:   Kuban State Agrarian University, Chikaeva Karina Surenovna
Published: October 2018

The study comprehensively presented the social characteristics of the nobility in Stavropol province. The author analyzed the materials of the Russian Imperial Census of 1897 and archives that demonstrated the composition, number, and literacy rate of the nobility. The social structure of the province was characterized by the fact that there were few noblemen (5,739) in this region compared to other territories of the Russian Empire; the proportion of nobility was only 0.66%. The nobles held a public office. Therefore, personal nobility predominated in the structure of the class (55%); a considerable part of it (77%) lived in urban areas. The research identified the significant differences of the local nobility which had been influenced by the historical circumstances of the regional development. The study revealed that the main part of hereditary noblemen (94%) was recorded in the second and third parts of genealogical books; they belonged to the mid- and top-ranking officials and officers. The author concluded that the number of noblemen in Stavropol province decreased rapidly in the early 20th century in line with common trends in the Russian Empire. Despite this fact, nobles were the majority of students and demonstrated the relatively high education level and literacy rate.
The interaction between capital and regional elites in the context of the cultural space development of a provincial city at the turn of the 19th–20th centuries
Authors:   Southern Ural State University of  Humanities and Education Science, Tatarkina Alfiya Ramilyevna
Published: October 2018

The study deals with the cultural space development in a provincial city in the context of modernization changes in the early 20th century dominated by the growth of social engagement in both provincial and capital societies. The cultural elite of the province, striving to qualitatively change the life of its native city and correspond to the capital trends and development level, expressed the innovative ideas and new trends. The cultural environment of small towns had been established with the help of outstanding Russian artists; their creative works and active citizenship set an example for the regional cultural elite. The interaction of elites in urban culture was reflected in various fields of activity from the artistic up to the cultural and educational ones. This process was uneven in the South Ural settlements and often dependent on objective circumstances.
‘I cannot say that the revolution has been totally unexpected,’ or How the ‘ocean of Russian people’ broke down
Authors: Skipina Irina Vasilyevna ,   Tyumen State University, Shcherbich Sofya Nikolaevna ,   Tyumen State University
Published: October 2018

The authors focus on the memories of the Tomsk provincial agronomist, public and state figure I.K. Okulich, who after the revolutionary events of 1917–1922 left his homeland and lived in exile. The manuscript of his memoirs is kept by the State Archives of the Russian Federation. Okulich’s memoirs are informative in nature, they reflect the events of 1917–1922 in Russia. By the time the memoirist wrote them, he had a great life experience. First, Okulich studied abroad. Then he worked as an agronomist in the provinces. He was a tsarist official in the Ministry of Agriculture as well. After the February Revolution, Okulich became a member of the Provisional Government. He knew many famous people of his time: Vologodsky, Prishvin, Pryanishnikov. Okulich was a special representative of the government of Admiral Kolchak responsible for financial oversight in the United States, Great Britain and France. He did his utmost to mitigate the situation in revolutionary Russia, but he was unable to change it. I.K. Okulich emigrated and spent his whole life trying to comprehend what he had experienced in 1917–1922. However, he had never recognized the power of the Bolsheviks.
Izhau: a Bashkir ladle for pouring koumiss. Archaic roots of a museum subject
Authors:   Bashkir State University, Nigmatullina Zilya Fasimovna
Published: October 2018

The study focuses on the wood-carved ladle that is a part of the koumiss utensils set for the Bashkirs. The ladle for pouring koumiss was made of a single piece of wood of different types by folk craftsmen in the second half of the 19th and the early 20th centuries. This household item, which is gracefully designed in the form of a waterfowl, mostly duck, has the archaic roots. There are many characters symbolizing a bird in the Bashkir mythology and folklore. Koumiss ladles are undoubtedly a source of study of both material and spiritual culture of the Bashkir people. The research deals with the ladles that are stored in the funds of the National Museum of the Republic of Bashkortostan, the Nesterov Bashkir State Art Museum, and the National Historical and Cultural Museum-Reserve Ancient Ufa.
Cognitive aspects of human subjectivity development
Authors:   Chechen State Pedagogical University, Betilmerzaeva Maret Muslamovna ,   Chechen State University
Published: October 2018

Philosophical comprehension of human as a social being in the research process cannot be fruitful in isolation from social reality, which has its own structure. The important structural elements of social reality include social space and social time whose dialectical interaction constructs a cultural and historical continuum. A person becomes a subject of this continuum in the cognitive process that is determined by the individual experience, social environment, and genetic potential. The main thesis of the research is that human subjectivity is a unique form of expression of the human self. Its productive study requires the return of the subject of analysis to a certain space-time continuum of the history of the subject (individual or social community). This provision has long been recognized. The novelty of the author’s approach in this regard is the explication of the mental aspects of the subjectivity development in the new paradigm of cognitive sciences.
Model Sistem Pakar Fuzzy Logic Method untuk Menentukan Status Akreditasi pada Sistem Informasi SAPTI Universitas Kristen Satya Wacana Berbasis Web
Authors: Lazuardi Bintang , Prasetyo Sri Yulianto Joko
Published: October 2018

Tujuan dari penelitian ini adalah menerapkan metode sistem pakar Fuzzy Logic Method pada Sistem Akreditasi Program Studi Internal (SAPTI) Universitas Kristen Satya Wacana berbasis teknologi web. Metode tersebut digunakan untuk menentukan status akreditasi pada setiap program studi yang direpresentasikan dalam bahasa pemrograman PHP, MySQL, Javascript, dan HTML. Status akreditasi ditentukan berdasarkan aturan-aturan variabel penentu. Selanjutnya dimasukkan kedalam basis pengetahuan sistem pakar dan dilakukan perhitungan secara matematis dengan menggunakan metode inferensi fuzzy Tsukamoto. Berdasarkan tahapan tersebut menghasilkan status akreditasi dengan beberapa kategori rentang nilai yaitu 0%-70% merupakan status gagal akreditasi, 70%-82.5% revisi akreditasi, dan 82.5%-100% sukses akreditasi.
Evaluation of the Aesthetic and Social Function of the Bendosari Park Salatiga City
Authors: Kristi Roynaldo , Simanjuntak M.Si Dr.Ir. Bistok Hasiholan
Published: October 2018

To function improve from the Bendosari park value, aesthetic and social function evaluation must be conducted. This study aims to evaluate the landscape characteristics of Bendosari Park based on aspects of the aesthetic and social function. The research was conducted in Bendosari Park on Ring Road of Salatiga City, Central Java Province, Indonesia from June until August 2017. Evaluation of the aesthetic and social function used close questionnaire method toward 30 respondents with respondents criteria of aged over 12 years and analyzed using KPI (Key Performance Indicator) method to find out how far the two aspects (the aesthetic and social) are reached. The study indicates that Bendosari Park has fulfilled the social and aesthetic functions of the park which indicated by the value of KPI analysis greater than 0.67.
BAKTERI AEROB PATOGEN DAN UJI KEPEKAAN ANTIMIKROBA DI RUANGAN PERAWATAN PENYAKIT DALAM
Authors: Raya Fedelia , Sennang Nurhayana , Aprianti Suci
Published: October 2018

Pathogenic bacteria are the major causes of airborne infection at the hospital ward. Nosocomial infection can occur at the opened as well as at the closed room. Nosocomial infection influences the morbidity and mortality in the hospital and need an extra attention, because of the increased number of hospital patients, micro organism mutation and increased of bacteria resistance to antibiotics. The aim of this study was to quantify the number of aerobic bacteria, and to know the pathogenic bacteria identification and its determination on the susceptibility of the antimicrobial problems at the internal medicine ward. This research was carried by a cross sectional study, which performed by collecting air samples in eight internal medicine ward of Dr. Wahidin Sudirohusodo Hospital using Microbiology Air Sampler 100 (MAS 100). The bacterial identification and the antimicrobial susceptibility test (AST) were conducted at the Balai Besar Laboratorium Kesehatan (July to August 2009). In this study were found the numbers of bacteria colonies about 580–6040 CFU/m3. The pathogenic bacteria that identified were Acinetobacter calcoaceticus, Staphylococcus saprohpyticus, Enterobacter hafniae and Stomatococcus mucilaginosus that were sensitive to Amikasin, Gentamicyn, Azitromycin and Norfloxacyn but resistant to Ampicillin. The number of bacterial colonies exceeded the established number standard by Decree of the Indonesian Health Minister. The pathogenic bacteria showed the most sensitive result of AST were Acinetobacter calcoaceticus, Enterobacter hafniae, Stomatococcus mucilaginosus and Staphylococcus saprohpyticus.
KORELASI FUNGSI HATI TERHADAP DERAJAT PENYAKIT DEMAM BERDARAH DENGUE ANAK
Authors: Kartini Ani , Mutmainnah Mutmainnah , Samad Ibrahim Abdul
Published: October 2018

Dengue Haemorrhagic Fever (DHF) may result acute liver failure. Although these cases are rare but is more common in children, and early identification of these infections is important to reduce the morbidity as well as mortality. The aim of this study was to know the determinations and the correlation of liver functions with the grade of Dengue Haemorrhagic Fever in children. This study was conducted by cross sectional, using data from the medical records of DHF patients who had liver function tests (AST, ALT, PT, aPTT and albumin) in the Laboratory of Clinical Pathology Dr. Wahidin Sudirohusodo Hospital Makassar from the period of July 2008 to June 2010. AST, ALT and albumin were tested using Cobas Integra 400, PT and aPTT were tested using Humaclot VA, and the data were analyzed with Spearman correlation test. There were fifty-five samples: 26 (47.3%) were males and 29 (52.7%) were females. We found 15 (27.3%) grade I, 13 (23.6%) grade II, 16 (29.1%) grade III and 11 (20%) grade IV patients. In this study are found that AST and ALT increased and there is a tendency of extending aPTT value but there was no significant correlation with the grade of DHF. The mean of albumin was lower in grade IV, there was a significant correlation between albumin and the grade of DHF (r=–0.375, p<0.05). In conclusion, there was a significant correlation between albumin and the grade of DHF. It is suggested that the routine albumin examination in DHF patients should be carried on to know whether a prevention of complications is needed to reduce the possibility of mortality.
KANKER OVARIUM DISGERMINOMA
Authors: Rahmawati Hegaria , ER Darmawaty , Pakasi Ruland DN
Published: October 2018

Ovarian cancer is a female reproductive organ malignancy and the second most common gynaecological type cancers. World Health Organisation classifies ovarian cancer based on their origin: superficial stroma-epithelium tumour, cord-stroma sex tumour, and germ cell tumour originated from germinal cells (yolk sac). Epithelium type of ovarian cancer is common, while the germinal type is rare and can be found in teenagers and young women aged 16-20 years old. A case of suspected dysgerminomas ovarian cancer grade IIIA was reported in a 12 years old girl. The diagnosis was established by tumour markers, USG/CT Scan of abdomen, surgery, and frozen section evaluations. The reviewer expected better survival prognosis after surgery and three cycles of chemotherapy combinations were executed. The evaluations of when serial tumour markers CA-125 were suggested during chemotherapy to detect any recurrences factors possibility of the related cancer.
MEAN PLATELET VOLUME DI STROK
Authors: Rosmiati Besse , Wibawa Sulina Y , ER Darmawaty
Published: October 2018

Ischemic stroke is the cause of most cases which occur due to obstruction, this pathogenesis can be caused by the formation of thrombus in the cerebrum blood vessels. Platelet aggregation plays a role in the pathogenesis of thromboembolic cerebrovascular disease. Platelets size, measured as Mean Platelet Volume (MPV) is a marker of platelet function and is associated with the indicator of platelet activity. Several studies have found that there was an increased of MPV in acute ischemic stroke while the correlation with the severity and outcome of stroke was still controversial. The aim of study is to determine the MPV and their association with outcomes in acute ischemic stroke patients. A cohort study during May up to July 2010 was carried out, the researchers measured MPV and analyze their correlation with its outcome using modified Rankin scale score 10 days after the onset in 33 acute ischemic stroke patients. The mean of MPV for the first three days of the onset was 8.9 fl, on the 5th day was increased up to 9.4 but at the 10th day of onset the MPV remains the same value as the 5th day. The MPV of first three days and 5th day have a positive correlation, but insignificant with their outcome, with p values 0.158 and 0.06, respectively. From this study can be concluded that the increased of MPV on the fifth day onset did not have any significant correlation with the outcome of acute ischemic stroke illness.
APOPTOSIS INDEX BETWEEN FEMALES AND MALES IN REGULAR HEMODIALYSIS
Authors: Santoso Djoko
Published: October 2018

Many reports have documented apoptosis index in hemodialysis patients, but to date, no single study has directly compared the apoptosis index of males to females. Data on mortality rate among hemodialytic patients in the hemodialysis center at the Department of Internal Medicine Dr Soetomo General Hospital, Surabaya, Indonesia show a high number predominated by female patients. Therefore, to answer the question of whether there is a gender difference in apoptosis index, the researcher studied leukocyte responses in male and female hemodialysis patients. The apoptosis index of the sample was measured by indirect immunoassay method. Cell lyses, followed by immunochemical determination of histone-complexed DNA fragments in a microtiter plate wells. The apoptosis quantization was obtained by determining the amount of colored product spectrophotometrically. One hundred and four non-diabetic subjects who received hemodialysis (HD), and 24 normal controls (NC), were evaluated. The apoptosis index in ESRD patients group and control group showed no significant difference (0.6172 vs 0.4008, p=0.114), neither did it vary in both sexes and age groups. When the sex factor was analyzed (after exclusion from the diabetic ESRD patients), females apoptosis index was significantly higher than that of the males (0.7325 vs 0.55175, p<0.05). In conclusion, apoptosis index in females among non-diabetic patients undergoing hemodialysis is higher than that occur in males and controls.
KOMPLEMEN SERUM C3C DAN LIMFOSIT T-CD4+ DARAH
Authors: Parwata I. Komang , Retnowati Endang , Tambunan Betty Agustina
Published: October 2018

The incidence of HIV and AIDS infection continues to increase despite various treatments have been applied, thus the mortality rate remains high. The examination of CD4+ T lymphocytes number to determine the immune status and the monitoring of therapy has some limitations in facilities and personnel examination as well as expensive costs. The decrease in CD4+ T lymphocytes number will be followed by an increase in the virus number and complement activation, so that the C3c complement levels will decrease. The purpose of this study was to know the correlation between C3c complement serum levels and CD4+ T lymphocytes number in stage I HIV-infected patients by determining them. This research is an observational cross-sectional study. Thirty samples of stage I HIV-infected patients at the UPIPI of Dr. Soetomo Hospital were included in this study; they were collected between July and August 2011. HIV diagnosis was confirmed by positive HIV test results using three different methods. The CD4+ T lymphocytes number were examined using flowcytometry (FACS Calibur, Becton Dickinson (BD) Diagnostics) and complement C3c using Radial Immunodiffusion (NOR Partigen * C3c, Siemens). The results of complement C3c serum levels and CD4 + T lymphocytes number were analyzed with Pearson's correlation and regression test (Pearson Product Moment Correlation) and Spearman's Correlation test. The majority (83.33%) of C3c complement levels in stage I HIV-infected patients was still within normal limits (0.55 g/L up to 2.01 g/L; mean 1.39 g/L, SD 0.313 g/L) while the majority of CD4+ T lymphocytes absolute number (80%) were decreased (24-567 cells/Î¼L; mean 295 cells/Î¼L, SD 177 cells/Î¼L). Based on a percentage value of CD4+ T lymphocytes, the majority (86.67%) decreased (2.54-29.48%; mean 13.58%, SD 6.7%). In this study was found that no significant correlation exists between C3c complement and CD4+ T lymphocyte absolute number with p=0.130 and percentage with p=0.217. There was no significant correlation of C3c complement and CD4+ T lymphocyte. This means that C3c complement examination can not be used to predict CD4+ T lymphocytes number.
EFEK SINERGIS KLOROKUIN DAN N-ACETYL CYSTEINE TERHADAP PENURUNAN PARASITEMIA DAN PENURUNAN KADAR MALONDYALDEHYDE ERITROSIT MENCIT YANG DIINFEKSI PLASMODIUM BERGHEI
Authors: Iskandar Agustin , Sudjari Sudjari
Published: October 2018

Malaria is still a global health problem around the world particularly in Indonesia. Chloroquine is one of the anti-malarial drugs which is still used in Indonesia. The aim of this research is to know the synergic effect of Chloroquine and N-Acetyl Cysteine towards parasitemia and erythrocyte malondyaldehyde levels in mice infected with Plasmodium berghei. This was an experimental research using Plasmodium berghei and BALB/c strain mice, 6âˆ’8 weeks old, with body weight 20âˆ’30 grams. After infected with Plasmodium berghei, the mice were divided into eight (8) groups: control, chloroquine, NAC 0.25 mg/gBb; NAC 0.5 mg/gBb; NAC 1 mg/gBb and combined drugs of chloroquine and NAC 0.25 mg/gBb; NAC 0.5 mg/gBb; NAC 1 mg/gBb. On the 3rd, 5th, and 7th day after treatment, the mice were killed and their parasitemia and Malondialdehyde (MDA) levels were measured. By using MANOVA and Tukey HSD test, a signifi cant difference in parasitemia level was found between the control and chloroquine group, as well as the control and combined drug groups. In the NAC groups, there was no decrease. The decrease of MDA level began on the 7th day. It can be concluded that there was a synergic effect between the chloroquine and N-Acetyl Cysteine in decreasing parasitemia and malondyaldehyde levels in mice BALB/c infected with Plasmodium berghei.
MANAJEMEN PENGETAHUAN UNTUK KESELAMATAN PASIEN
Authors: Hartono Hartono , Subarniati Rika , Pudjirahardjo Widodo J. , Judajana FM.
Published: October 2018

Many mistakes are often made in the laboratory such as: confusing results of specimen examination, wrong process of laboratory services and many problems appearing during services can result in patient's error. The knowledge management can be a systematically way to capture and communicate knowledge to the laboratory technicians in order to minimize errors made in the laboratory. The purpose of this study is to prove that by implementation of patient's safety using management strategy of knowledge about patient's safety can increase the performance of laboratory personnel. The study is carried out pre-experimentally by using a pre-post design in a group without a control group comprising 55 respondents. Prior to giving implementation about knowledge of patient's safety, the study subjects were tested by a pre-test about: the personnel's potentials (mindset, attitude, awareness and knowledge), quality of work and performance of the personnel. Knowledge management was implemented in several stages, starting from dispersion of knowledge by making: modules, stages of setting up a team, distribution of knowledge by training and executing patient's safety and acquainting knowledge by routine team meetings, recording, reporting and evaluation of patient's safety. The increase of potentials, work process quality and personnel performance was post-tested to show a change and implementation effect of knowledge management about patient's safety. The result showed a significant change in the personnel potentials post implication of knowledge management (p<0.001). A significant change was also shown in increase work quality (p<0.001). The influence of potential increase of work process quality showed a significant correlation (p=0.172, Î²=01.87). The increase of personnel potentials also influenced the improvement of their performance (p=0.002, Î²: 0.406). However, the increase of personnel work process quality significantly influenced the improvement of personnel performance (p<0.001, (Î²=0.581) Based on this study it can be concluded that knowledge management about patient's safety can influence the increase of potentials and quality of personnel work process. The increase of quality on the personnel work process can significantly influence the improvement of personnel performance as well.
PROKALSITONIN, CRP DAN PRESEPSIN SERUM DI SIRS
Authors: Hendrianingtyas Hendrianingtyas , RH Banundari , KS Indranila , Budiwiyono Imam
Published: October 2018

Infection in ICU patients can lead to a septic condition with clinical signs similar to Systemic Inflammatory Response Syndrome (SIRS). The high risk of death and high cost of sepsis is the reason to find an early marker in diagnosing sepsis. Blood culture can givea result in 1-3 days, so C reactive protein, procalcitonin and presepsin which are fast and accurate are needed to find a septic condition in SIRS patients. The aim of this study is to determine the diagnostic value of CRP, PCT and presepsin of sepsis with blood culture as the gold standard., The samples were collected from 32 clinically SIRS patients in the Dr. Kariadi Hosiptal, Semarang. The PCT level was measured using ELFA method, CRP level by PET IA method, while presepsin level by CLEA method. The determined area was under curve (AUC) and the cut off level was determined by 2í—2 table to find out the sensitivity, spesificity, positive predictive value, negative predictive value and likelihood ratio of CRP, PCT and presepsin as well. The AUC of PCT, CRP and presepsin was 0.78 (cut off 4.314 ng/mL); 0.673 (cut off 10.245 mg/L) and 0.814 (cut off 1134.5 pg/mL). The presepsin level had a higher sensitivity (90%) than PCT (80%) and CRP (70%). PCT specificity was 72.73%, presepsin and CRP specificity each was 68.18%. Based on this study, AUC and sensitivity of presepsin level were found higher than the PCT and CRP level.
Heterogeneity of clinical presentation in Tako-Tsubo syndromes: the prevalence of normal segmental wall motion and normal ECG pattern
Authors: Rellini Gianluigi , Piazza Rita , Loiudice Elvira , Cassin Matteo , Bernardi Guglielmo , Pavan Daniela , Cervesato Eugenio , Nicolosi Gian L.
Published: October 2018

Aim

The aim of this study is to report the heterogeneity of clinical presentation in Tako-Tsubo syndrome (TTS), including a significant prevalence of normal ECG and echocardiographic patterns in a series of consecutive patients from a single center.

Methods and results

From our database we selected a total of 168 cases of TTS. A total of 140 of these (Group A); 14 men (10%), mean age 60.3 years, range 39–87; 126 women (90%), mean age 66.1 years, range 43–93; matched the following reported criteria: typical stenocardic pain immediately following an emotional acute stress, or acute medical or surgical event within the preceding 12 h; acute rise and fall of troponin release; absence of significant coronary disease at coronary angiography. ECG findings at presentation ranged from T wave abnormalities (41 cases, 29.3%) to ST elevation (52 cases, 37.1%) and ST depression (11 cases, 7.9%), whereas in 36 cases (25.7%) the ECG was normal. Echocardiography at presentation showed akinesia of the total apical or medium-apical segments in 74 patients (53%), whereas it showed akinesia of left ventricular wall segments in other locations in 30 patients (21%) and even normal regional wall motion and thickening in 36 patients (26%). We described also a series of 13 female patients (mean age 70.2 years; age range 45–85 years) (Group B) who did not complain of chest pain at presentation, but showed a classical Tako-Tsubo evolution of wall motion abnormalities at echocardiography. Finally we selected 15 female patients (mean age 69.3 years; age range 49–89 years) (Group C) who formally did not report acute stress immediately preceding their presentation to the hospital for chest pain. They showed a classical Tako-Tsubo evolution of wall motion abnormalities at echocardiography and only one case of normal ECG pattern at presentation.

Conclusion

In this series of acute TTS, a wide variability of ECG and echocardiographic patterns are observed, ranging from ST elevation with coexisting segmental wall motion abnormalities of the typical TTS to a clinical presentation characterized by normal ECG and normal segmental wall motion pattern.
O Colégio Agrícola de Francisco Beltrão/PR e os desafios da Educação Politécnica
Authors: Costa Nara Tatiana , Antonio Clésio Acilino
Published: October 2018

Síntese dissertação Mestrado em Educação Unioeste de Francisco Beltrão/PR, propôs-se discutir desafios da educação politécnica no Colégio Agrícola de Francisco Beltrão. Estudo de caso, exploratório, observação participante e entrevistas foi desenvolvido tencionando compreender o campo e a relação com jovens; identificar elementos da Educação Politécnica e experiências; caracterizar o projeto educativo de Ensino Médio e Profissional;  analisar a relação trabalho e educação e as práticas pedagógicas desenvolvidas. Como resultado a compreensão das práticas pedagógicas relacionadas à teoria e prática, conhecimentos científicos e capacidades técnicas envolvidas. As considerações demarcam os princípios da politecnia como importante para um projeto educativo do trabalhador.
A Educação Ambiental no Ensino de Administração – desafios e perspectivas
Authors: Malta Suzana de Oliveira , Calloni Humberto
Published: October 2018

ResumoFormar administradores comprometidos com a questão ambiental e atuantes nas organizações constitui-se como um dos desafios atuais para as Instituições de Ensino Superior. Este artigo pretende contribuir com a reflexão sobre o processo de inserção da Educação Ambiental nos cursos de graduação em Administração. Ele apresenta uma contextualização de alguns marcos do desenvolvimento do ensino de Administração no Brasil e da Educação Ambiental para, em seguida, apresentar um panorama de como essa temática tem sido trabalhada no ensino superior e, mais especificamente, no ensino de Administração.Palavras-chave: Educação Ambiental; Ensino de Administração; Desafios; Perspectivas.
A “força theorica do methodo intuitivo”: proposições de Justiniano de Mello e Silva para a educação das crianças no século XIX
Authors: Silva Santos Bárbara , Jesus Ferronato Cristiano , Santos Anderson
Published: October 2018

No cerne dessas discussões e posterior à forte defesa da validação do método intuitivo, Justiniano de Mello, político, jornalista e professor, não poderia deixar de apresentar o seu posicionamento quanto às configurações da educação do seu tempo. Logo, delineamos, neste estudo, os princípios do método intuitivo elencados por este intelectual, os quais foram publicados em seus textos no jornal Sete de Março entre anos 1888 e 1891.
Toward Learned Chemical Perception of Force Field Typing Rules
Authors: Zanette Camila , Bannan Caitlin C. , Bayly Christopher I. , Fass Josh , Gilson Michael , Shirts Michael R. , Chodera John , Mobley David
Published: October 2018

Molecular mechanics force fields define how the energy and forces of a molecular system are computed from its atomic positions, and enable the study of such systems through computational methods like molecular dynamics and Monte Carlo simulations. Despite progress toward automated force field parameterization, considerable human expertise is required to develop or extend force fields. In particular, human input has long been required to define atom types, which encode chemically unique environments that determine which parameters must be assigned. However, relying on humans to establish atom types is suboptimal: the resulting atom types are often unjustified from a statistical perspective, leading to over- or under-fitting; they are difficult to extend in a systematic and consistent manner when new chemistries must be modeled or new data becomes available; and human effort is not scalable when force fields must be generated for new (bio)polymers or materials. We aim to replace human specification of atom types with an automated approach, based on solid statistics and driven by experimental and/or quantum chemical reference data. Here, we describe a novel technology for this purpose, termed SMARTY, which generalizes atom typing by using direct chemical perception with SMARTS strings, and adopting a hierarchical approach to type assignment. The SMARTY technology enables creation of a move set in atom-typing space that can be used in a Monte Carlo optimization approach to atom typing. We demonstrate the power of this approach with a fully automated procedure that is able to re-discover human-defined atom types in the traditional small molecule force field parm99/parm@Frosst. Furthermore, we show how an extension of this approach that makes use of SMIRKS strings to match multiple atoms, which we term SMIRKY, allows us to take full advantage of the advances in direct chemical perception for valence types (bonds, angles, and torsions) afforded by the recently-proposed SMIRNOFF direct chemical perception force field typing language. We assess these approaches using several molecular datasets, including one which covers a diverse molecular subset from DrugBank.
An Amphiphilic-DNA Platform for the Design of Crystalline Frameworks with Programmable Structure and Functionality
Authors: Brady Ryan A. , Brooks Nicholas J. , Foderà Vito , Cicuta Pietro , Di Michele Lorenzo
Published: October 2018

The reliable preparation of functional, ordered, nanostructured frameworks would be a game changer for many emerging technologies, from energy storage to nanomedicine. Underpinned by the excellent molecular recognition of nucleic acids, along with their facile synthesis and breadth of available functionalizations, DNA Nanotechnology is widely acknowledged as a prime route for the rational design of nanostructured materials. Yet, the preparation of crystalline DNA frameworks with programmable structure and functionality remains a challenge. Here we demonstrate the potential of simple amphiphilic DNA motifs, dubbed C-stars, as a versatile platform for the design of programmable DNA crystals. In contrast to all-DNA materials, in which structure depends on the precise molecular details of individual building blocks, the self-assembly of C-stars is controlled uniquely by their topology and symmetry. Exploiting this robust self-assembly principle we design a range of topologically identical, but structurally and chemically distinct C-stars that following a one-pot reaction self- assemble into highly porous, functional, crystalline frameworks. Simple design variations allow us to fine-tune the lattice parameter and thus control the partitioning of macromolecules within the frameworks, embed responsive mo- tifs that can induce isothermal disassembly, and include chemical moieties to capture target proteins specifically and reversibly.
GERAK KOMUNITAS FIKSIMINI DI RUANG SIBER
Authors: Rokib Mohammad
Published: October 2018

Perkembangan teknologi infomasi yang sangat pesat di Indonesia telah mencip-takan ruang baru dunia sastra. Ragam karya sastra meruah dan menjelma dalam bentuk baru dunia siber yang menonjolkan indra visual. Selera sastra pada gilirannya membentuk citranya sendiri dengan desain semacam genre baru yang berusaha bergerak melampaui ruang sebagaimana gerakan komunitas “fiksimini”. Kelompok itu mampu memopulerkan mini karya sastra yang dianggap ringkas tanpa menegasikan esensi karya sastra. Komunitas Fiksimini mampu menciptakan sensibilitas baru yang membuat masyarakat berselera terhadap karya sastra? Melalui paradigma pascastrukturalis mode of information (Mark Poster), tulisan ini berusaha menyajikan deskripsi konteks kecenderungan sastra baru sebagaimana kehadiran komunitas fiksimini. Tulisan ini menggunakan metode deskriptif dalam usaha memahami gerak komunitas fiksimini di ruang jejaring sosial dan situs web. Apabila dalam masyarakat modern (strukturalis) yang dominan adalah media tulisan fisik dan percetakan yang bersifat mekanik, konteks masyarakat mutakhir (pascastrukturalis) cenderung termediasi oleh media audiovisual yang bersifat elektronik. Kemunculan komunitas itu merupakan aktualisasi kebudayaan mutakhir yang menciptakan sensibilitas baru serta membentuk citra indrawi yang bermacam-macam dengan mudah melalui media elektronik.Kata kunci: ruang siber, komunitas fiksimini, sensibilitas baru
PROSA DAN KEHIDUPAN KOTA
Authors: Al Qadri Ridha
Published: October 2018

Tulisan ini mengeksplorasi relasi antara karya sastra dan sejumlah fakta sosial di perkotaan Indonesia dalam rentang tiga zaman (normal-khaos-normal) hingga zaman global. Terdapat tiga hal yang dicermati, di antaranya (1) segregasi spasial di perkotaan sepanjang peralihan tiga zaman tersebut, yaitu era kolonialisme hingga kemerdekaan, (2) strategi kelas sosial di ruang perkotaan, khususnya dalam gambaran karya sastra pada zaman yang berubah-ubah tersebut, dan (3) respons parodi-romantik dalam karya sastra atas kontradiksi kota hingga zaman global, yang meliputi krisis keintiman warga kota.
KARAKTERISTIK PEMAKAIAN BAHASA DALAM TULISAN PADA BODI BEMO DAN TRUK DI SURABAYA
Authors: Subiyatningsih Foriyani
Published: October 2018

Penelitian ini bertujuan mendeskripsikan karakteristik pemakaian bahasa dalam tulisan pada bodi bemo dan truk di Surabaya. Penelitian ini menggunakan pendekatan deskriptif. Data penelitian adalah penggunaan satuan lingual berupa kata, frasa, klausa, dan kalimat pada bodi bemo dan truk yang melintas di sepanjang jalan di Surabaya dan tulisan pada truk yang dimuat di internet. Penyediaan data dilakukan dengan menggunakan metode simak dan catat, dengan teknik sadap dan dengan teknik lanjutan teknik catat. Analisis data menggunakan metode agih (beserta teknik-tekniknya). Penelitian ini menghasilkan hal-hal, antara lain berupa (1) perubahan fonem, (2) pelesapan dan penambahan fonem, (3) kata bahasa Inggris dibaca dengan lafal bahasa Indonesia atau bahasa Jawa, (4) kata bahasa Inggris ditulis sesuai dengan lafal bahasa Indonesia, (5) bilangan dan angka sebagai representasi huruf, suku kata, atau kata, (6) singkatan, (7) akronim, (9) bentuk plesetan, (10) penulisan kata yang bervariasi, dan (12) tulisan yang disertai lukisan.
PERGESERAN PEMAKAIAN PRONOMINA PERSONA DALAM BAHASA INDONESIA “GAUL”
Authors: Prayogi Icuk
Published: October 2018

Berbicara ragam gaul bahasa Indonesia sekarang ini pastilah pikiran tertuju pada “bahasa” Alay. Jauh sebelum itu, sebenarnya ragam gaul telah ada. Hanya, Alay yang sekarang muncul adalah perubahan dari ragam gaul pada zaman dulu. Karena beberapa hal, bentuk dan aturan pemakaian ragam ini dimungkinkan berubah. Pemakaian pronomina persona juga dimungkinkan mengalami atau pergeseran (shift). Pronomina persona kau atau saya, misalnya, akan sungguh terasa janggal bila diucapkan remaja zaman sekarang dalam konteks percakapan normal dengan remaja lain di Jakarta. Oleh karena itu, makalah sederhana ini membahas tentang pronomina persona apa saja yang mengalami pergeseran serta bagaimana pergeseran pemakaian pronomina persona dalam bahasa Indonesia “gaul”. Dengan metode kualitatif dan data dari berbagai sumber (terutama film), diharapkan menghasilkan gambaran yang cukup tentang pergeseran ini serta mengapa hal ini sampai terjadi.
Considerações éticas acerca da proteção da infância frente à prevalência de excesso de peso.
Authors: Dratch Carolina , Rosaneli Caroline , Silva Dillian , Cunha Thiago , Biscioni Diego
Published: October 2018

O excesso de peso na infância potencializa a vulnerabilidade e a fragilidade desta fase do curso da vida. O aumento da prevalência do excesso de peso e de suas complicações na infância pode ser problematizado como impedimento ao alcance do potencial de desenvolvimento humano e do aprofundamento de suas vulnerabilidades frente às condições de saúde. Este trabalho trata de uma revisão crítica. sustentada em pesquisa teórica no campo da bioética e da saúde pública, apresentando as implicações para a infância perante a prevalência de excesso de peso, acerca das temáticas sobre vulnerabilidade, proteção e promoção a saúde. Considerações éticas sobre as condutas de proteção da infância podem auxliar no planejamento de estratégias de apoio à mudança de comportamentos e de manutenção da boa qualidade de vida, levando á formação dos individuos cuidadores de si e da infância, de uma consciência crítica a respeito dos probelmas de saúde e de seus fatores de risco.
A relacionalidade como fundamento da autonomia
Authors: Schpallir Maria , Anjos Márcio
Published: October 2018

O atual momento histórico tem sido o cenário em que se tem postulado uma autonomia plena, entendida na sociedade mercadológica de forma centralizada em interesses particulares excludentes. A moralidade dessa exaltação da autonomia nega a alteridade, na medida em que legitima a utilização do outro, transformando-o de sujeito em objeto. Entretanto, a autonomia, como entendida na filosofia moderna, cujo expoente foi Kant, é basicamente relacional. Relacionalidade é aqui entendida como a condição humana que se torna exigência ética na interação entre seres humanos. O trabalho propõe-se a verificar o alcance da relacionalidade para fundamentar a concepção ética de autonomia. Consiste em estudo bibliográfico hermenêutico argumentativo em torno da concepção kantiana de autonomia e da sua interpretação vigente nos atuais contextos, que a restringe aos indivíduos. Para tanto considera aspectos socioculturais, políticos e econômicos, condicionantes de tal interpretação; contrapõe as exigências da relacionalidade implícitas na conceituação kantiana da autonomia; e conclui pela necessária inclusão das exigências da relacionalidade na concepção ética da autonomia, superando seu confinamento ao âmbito dos indivíduos.
Slow Food sob o olhar da bioética, em busca de alimentação saudável
Authors: Denti Fausto , Anjos Márcio
Published: October 2018

O Slow Food é um movimento crítico ao Fast Food e defende uma boa alimentação em vista de melhor qualidade de vida. Respondendo ao ritmo acelerado dos tempos modernos, foram adotadas escolhas nutricionais rápidas e práticas através de alimentos industrializados. O Movimento Slow Food tem um olhar crítico implícito sobre a qualidade de tais alimentos e seus correspondentes hábitos alimentares; e considera que eles contêm componentes prejudiciais à saúde, ao paladar na alimentação e ao seu valor nutritivo, se comparados com os padrões não industrializados de produção e de tempo para as refeições. Este estudo visa explicitar através de olhar latinoamericano da Bioética alguns aspectos da incidência do Movimento Slow Food, na consciência crítica sobre o sentido da boa alimentação. Por método bibliográfico recolhe elementos da literatura nacional recente sobre o tema; e através de um método hermenêutico heurístico busca interpretar significados éticos e políticos do alimentar-se e consequentes exigências de uma consciência crítica nos tempos tecnológicos, condizentes com o pensar bioético.
Biochemical profile of blood in naturally occurring Sarcocystis infection in cattle
Authors: Januškevičius Vytautas , Januškevičienė Gražina , Banys Antanas , Dailidavičienė Jurgita , Aniulienė Albina
Published: October 2018

The aim of this study was to determine the biochemical blood indicators in Lithuanian Black-and-White cattle with regard to the intensity of their infection with Sarcocystis spp. In total 945 bull muscle samples and 120 blood samples were used for the analysis. Aspartate aminotransferase (AST), alkaline phosphatase (ALP), and alanine aminotransferase (ALT) were increased in infected animals relative to uninfected animals. The AST levels differed significantly between the no infection, low, and moderate infection groups (P < 0.05); ALP differed between the no infection and moderate infection groups (P < 0.05); and ALT differed between the no infection, low infection and intense infection groups (P < 0.05). Total protein levels were higher than physiological limits and differed significantly between the no infection, low infection and intense infection groups (P < 0.05). Iron levels were at the lowest physiological limits and differed significantly between the no infection and low infection groups, as well as between the low infection and intense infection groups (P < 0.05). Triglyceride levels were at their physiological limits, and differed significantly between all examined groups (P < 0.05). The results show that changes in the biochemical markers ALP, AST and ALT are related to the intensity of the Sarcocystis spp. infection.