bluuebunny/crossref_metadata_2025 huggingface dataset:
The immediate-early protein 1 of human herpesvirus 6B interacts with NBS1 and inhibits ATM signaling
Authors: Collin Vanessa , Biquand Élise , Tremblay Vincent , Lavoie Élise G , Blondeau Andréanne , Gravel Annie , Galloy Maxime , Lashgari Anahita , Dessapt Julien , Côté Jacques , Flamand Louis , Fradet-Turcotte Amélie
Published: January 2024

Viral infection often trigger an ATM serine/threonine kinase (ATM)-dependent DNA damage response in host cells that suppresses viral replication. Viruses evolved different strategies to counteract this antiviral surveillance system. Here, we report that human herpesvirus 6B (HHV-6B) infection causes genomic instability by suppressing ATM signaling in host cells. Expression of immediate-early protein 1 (IE1) phenocopies this phenotype and blocks homology-directed double-strand break repair. Mechanistically, IE1 interacts with NBS1, and inhibits ATM signaling through two distinct domains. HHV-6B seems to efficiently inhibit ATM signaling as further depletion of either NBS1 or ATM do not significantly boost viral replication in infected cells. Interestingly, viral integration of HHV-6B into the host’s telomeres is not strictly dependent on NBS1, challenging current models where integration occurs through homology-directed repair. Given that spontaneous IE1 expression has been detected in cells of subjects with inherited chromosomally-integrated form of HHV-6B (iciHHV-6B), a condition associated with several health conditions, our results raise the possibility of a link between genomic instability and the development of iciHHV-6-associated diseases.
A conserved ion channel function of STING mediates noncanonical autophagy and cell death
Authors: Xun Jinrui , Zhang Zhichao , Lv Bo , Lu Defen , Yang Haoxiang , Shang Guijun , Tan Jay Xiaojun
Published: January 2024

The cGAS/STING pathway triggers inflammation upon diverse cellular stresses such as infection, cellular damage, aging, and diseases. STING also triggers noncanonical autophagy, involving LC3 lipidation on STING vesicles through the V-ATPase-ATG16L1 axis, as well as induces cell death. Although the proton pump V-ATPase senses organelle deacidification in other contexts, it is unclear how STING activates V-ATPase for noncanonical autophagy. Here we report a conserved channel function of STING in proton efflux and vesicle deacidification. STING activation induces an electron-sparse pore in its transmembrane domain, which mediates proton flux in vitro and the deacidification of post-Golgi STING vesicles in cells. A chemical ligand of STING, C53, which binds to and blocks its channel, strongly inhibits STING-mediated proton flux in vitro. C53 fully blocks STING trafficking from the ER to the Golgi, but adding C53 after STING arrives at the Golgi allows for selective inhibition of STING-dependent vesicle deacidification, LC3 lipidation, and cell death, without affecting trafficking. The discovery of STING as a channel opens new opportunities for selective targeting of canonical and noncanonical STING functions.
ZSWIM4 regulates embryonic patterning and BMP signaling by promoting nuclear Smad1 degradation
Authors: Wang Chengdong , Liu Ziran , Zeng Yelin , Zhou Liangji , Long Qi , Hassan Imtiaz Ul , Zhang Yuanliang , Qi Xufeng , Cai Dongqing , Mao Bingyu , Lu Gang , Sun Jianmin , Yao Yonggang , Deng Yi , Zhao Qian , Feng Bo , Zhou Qin , Chan Wai Yee , Zhao Hui
Published: January 2024

The dorsoventral gradient of BMP signaling plays an essential role in embryonic patterning. Zinc Finger SWIM-Type Containing 4 (zswim4) is expressed in the Spemann-Mangold organizer at the onset of Xenopus gastrulation and is then enriched in the developing neuroectoderm at the mid-gastrula stages. Knockdown or knockout of zswim4 causes ventralization. Overexpression of zswim4 decreases, whereas knockdown of zswim4 increases the expression levels of ventrolateral mesoderm marker genes. Mechanistically, ZSWIM4 attenuates the BMP signal by reducing the protein stability of SMAD1 in the nucleus. Stable isotope labeling by amino acids in cell culture (SILAC) identifies Elongin B (ELOB) and Elongin C (ELOC) as the interaction partners of ZSWIM4. Accordingly, ZSWIM4 forms a complex with the Cul2-RING ubiquitin ligase and ELOB and ELOC, promoting the ubiquitination and degradation of SMAD1 in the nucleus. Our study identifies a novel mechanism that restricts BMP signaling in the nucleus.
Nuclear Magnetic Relaxation and Molecular Dynamics
Authors: Kimmich Rainer
Published: January 2024

Interested in analysing complex systems? Have you considered nuclear magnetic relaxation studies to derive sound conclusions? Here’s how.

Nuclear Magnetic Resonance (NMR) relaxation techniques form a family of powerful tools to study and characterize liquid, solid or semi-solid materials and systems. They provide access to details directly and in wide variable ranges. This book outlines the unparalleled potential of NMR relaxation experiments to elucidate molecular dynamics. The key concepts discussed are correlation functions and spectral densities of the thermal fluctuations of spin interactions.

For users working in technology, chemical engineering, materials science, biomedicine, food science, geophysics and physical chemistry, the text explores the principles, theoretical background and descriptions of typical applications. As an essential part of relaxation data, the focus is on the statistical features of molecular dynamics. The aim is to assist the reader to acquire meaningful nuclear magnetic relaxation data sets and develop appropriate statistical models as a basis for their interpretation.

This unique text is targeted to anyone performing or interested in NMR relaxation experiments from undergraduates to academics and those in industry.
Hit optimization by dynamic combinatorial chemistry on Streptococcus pneumoniae energy-coupling factor transporter ECF-PanT
Authors: Exapicheidou Ioulia Antonia , Shams Atanaz , Ibrahim Hamza , Tsarenko Aleksei , Backenköhler Michael , Hamed Mostafa M. , Diamanti Eleonora , Volkamer Andrea , Slotboom Dirk J. , Hirsch Anna K. H.
Published: January 2024

First application of dynamic combinatorial chemistry to the whole complex of the energy-coupling factor transporter PanT from Streptococcus pneumoniae.
Modulation of ΔEST and room temperature phosphorescence in carbazole derivatives
Authors: Barhate Komal Vasant , Wadawale Amey P. , Chandrakumar K. R. S. , Agarwal Neeraj
Published: January 2024

ΔEST is correlated with the singlet and triplet excited state dipole moment and RTP was observed.
Non-classical (NC), heptagon-containing fullerenes obtained via chlorination-promoted cage transformations: C76(NC2a)Cl24 and C76(NC2b)Cl28
Authors: Brotsman Victor A. , Troyanov Sergey I.
Published: January 2024

High-temperature chlorination of fullerene C76 with SbCl5 promotes skeletal transformation to non-classical, non-IPR C76(NC2a)Cl24via five SWRs. C76(NC2b)Cl28 with isomeric carbon cage was obtained by chlorination of C80 with VCl4via two C2 losses.
A dendritic porous copper foam-carbonic anhydrase biohybrid for carbon dioxide electroreduction
Authors: Shu Minli , Miao Boqiang , Zhang Siqi , Wang Zhe , Zhu Xuefang , Jiang Yucheng , Chen Yu
Published: January 2024

Carbonic anhydrase (CA) is bound to a dendritic porous copper foam (3D-Cu) via electrostatic interaction to form a biohybrid (CA/3D-Cu), which exhibits high selectivity and FE in the electroreduction CO2 to formic acid due to high specific surface area and ultrahigh CO2 hydration capacity of CA.
A dye sensitized photosynthesis cell for stable water oxidation mediated by photo-generated bromine
Authors: Fei Ling , Guo Xiao , Liang Dan , Lei Lei , Wang Degao
Published: January 2024

The water oxidation process at the sensitization–oxidation photo-anode by photo-generated bromine.
Iridium-catalyzed selective arylation of B(6)–H of 3-aryl-o-carboranes with arylboronic acid via direct B–H activation
Authors: Yang Han-Bo , Guo Yan , Cao Ke , Jiang Qi-Jia , Teng Chao-Chao , Zhu Dao-Yong , Wang Shao-Hua
Published: January 2024

This work discloses an iridium-catalyzed selective arylation of B(6)–H of 3-Ar-o-carboranes with arylboronic acid via direct B–H activation for the first time.
Reduction of intracellular oxidative stress with a copper-incorporated layered double hydroxide
Authors: Szerlauth Adél , Madácsy Tamara , Samu Gergely Ferenc , Bíró Péter , Erdélyi Miklós , Varga Gábor , Xu Zhi Ping , Maléth József , Szilágyi István
Published: January 2024

Structural modification of 2-dimensional clay nanoparticles led to the development of biocompatible antioxidant nanozymes to combat intracellular oxidative stress.
PtS2/GeC van der Waals heterostructure: a promising direct Z-scheme photocatalyst with high solar-to-hydrogen energy conversion efficiency for overall water splitting under acidic, alkaline, and neutral conditions and in large-strain regions
Authors: Ding Jian-Xin , Zhang Yan , Xie Kang-Xin , Qiang Zhi-Bo , Chen Hua-Xin , Duan Li , Ni Lei , Fan Ji-Bin
Published: January 2024

In this study, first-principles calculations were used to investigate in detail the structural, electronic, optical, and photocatalytic properties of PtS2/GeC heterostructures.
Towards hybrid quantum mechanical/molecular mechanical simulations of Li and Na intercalation in graphite – force field development and DFTB parametrisation
Authors: Purtscher Felix R. S. , Hofer Thomas S.
Published: January 2024

The QM/MM simulation protocol, previously developed for solid-state interfaces, has been extended for the investigation of graphitic carbon materials. To study the intercalation of Li in graphite, new DFTB parameters for Li have been formulated.
Experimental and computational DFT, drift-diffusion studies of cobalt-based hybrid perovskite crystals as absorbers in perovskite solar cells
Authors: Marimuthu Sathish , Pandiaraj Saravanan , Muthuramamoorthy Muthumareeswaran , Alzahrani Khalid E. , Alodhayb Abdullah N. , Pitchaimuthu Sudhagar , Grace Andrews Nirmala
Published: January 2024

Lead-free perovskite crystals are synthesized and studied using density functional theory. drift-diffusion modelling identifies optimal cell performance by varying parameters.
Structures of multinuclear U(vi) species on the hydroxylated α-SiO2(001) surface: insights from DFT calculations
Authors: Gao Pengyuan , Jin Qiang , Chen Zongyuan , Wang Dongqi , Tournassat Christophe , Guo Zhijun
Published: January 2024

The structures, energetics, and mechanism of three multinuclear U(vi) species adsorbed onto the α-SiO2(001) surface were investigated using density functional theory calculations.
Anchoring and catalytic insights into bilayer C4N3 material for lithium–selenium batteries: a first-principles study
Authors: Yang Zehui , Liu Wentao , Bai Shulin , Ai Peng , Wang Hao , Zheng Tuo , Li Qingshun , Tang Shuwei
Published: January 2024

A theoretical design for the viability of bilayer C4N3 as a promising host material in Li–Se battery is conducted by first-principles calculations.
Engineering organic polymers as emerging sustainable materials for powerful electrocatalysts
Authors: Cui Xun , Wu Mingjie , Liu Xueqin , He Bing , Zhu Yunhai , Jiang Yalong , Yang Yingkui
Published: January 2024

A comprehensive overview on organic polymers as electrocatalysts is summarized. By presenting the engineering strategies, insightful understandings, challenges, and perspectives, we hope this review can provide valuable references for the readers.
Oxidative functionalization of yndiamides catalyzed by gold(i) or Brønsted acid systems: computational study of mechanism, selectivity patterns, and effects of substituents
Authors: Yan Guowei , Ma Ji , Qi Simeng , Kirillov Alexander M. , Yang Lizi , Fang Ran
Published: January 2024

The mechanism, selectivity and the effects of substituents were explored using density functional theory in the oxidative functionalization of yndiamides catalysed by [IPrAuNTf2] or [HNTf2] systems.
A fast and scalable computational topology framework for the Euler characteristic
Authors: Laky Daniel J. , Zavala Victor M.
Published: January 2024

Parallel algorithms exploit structure to compute the Euler characteristic (a powerful topological descriptor that is used to quantify shape of data) at significantly less computational expense than traditional software tools.
Polydiacetylene/lipid-coated red-emissive silica nanorods for the sustained release and ameliorated anticancer efficacy of a Ru(arene) complex bearing piperlongumine natural product
Authors: Ishaniya Wickneswaran , Sumithaa Chezhiyan , Subramani Muthuraman , Karanath-Anilkumar Aswathy , Munuswamy-Ramanujam Ganesh , Madan Kumar Arumugam , Rajendran Saravanakumar , Ganeshpandian Mani
Published: January 2024

Polydiacetylene/lipid-coated silica nanorods for Ru(p-cymene)-piperlongumine complex delivery towards cancer cells.
New heterometallic Co/Zn, Ag/Co, and Ag/Zn imidazolates: structural characterization and catalytic activity in the oxidation of organic compounds
Authors: Lopresti Mattia , Kurowski Łukasz , Palin Luca , Milanesio Marco , Siedzielnik Magdalena , Gutmańska Karolina , Dobrenko Adriana , Klimczuk Tomasz , Pawelczyk Ewelina , Dołęga Anna
Published: January 2024

Nanocrystalline powders of heterometallic Co/Zn, Ag/Zn and Ag/Co imidazolates were produced by a reaction carried out in water at room temperature. Ag2Co(Im)4, exhibits certain catalytic activity in the oxidation reaction of 1-phenylethanol with tert-butylhydroperoxide.
Photo-induced valence tautomerism and polarization switching in mononuclear cobalt complexes with an enantiopure chiral ligand
Authors: Xu Wen-Huang , Huang Yu-Bo , Zheng Wen-Wei , Su Sheng-Qun , Kanegawa Shinji , Wu Shu-Qi , Sato Osamu
Published: January 2024

We report the discovery of a novel valence tautomeric cobalt mononuclear compound with a chiral ligand, which enhances the efficiency of light-induced polarization switching.
Chronic exposure to parabens promotes non-alcoholic fatty liver disease in association with the changes of the gut microbiota and lipid metabolism
Authors: Ren Yilin , Shi Xinyi , Mu Jing , Liu Shenyin , Qian Xin , Pei Wenlong , Ni Shanhong , Zhang Zhengduo , Li Lei , Zhang Zhan
Published: January 2024

Chronic exposure to MeP and EtP promoted NAFLD via gut microbiota-dependent AA metabolism.
Effect of liquid aerosol temperature on the detection performance of LIBS for analysis of phosphorus element in water
Authors: Yang Xinyan , Wang Xin , Li Dongdong , Zhang Xu , Li Kuohu , Ren Hongmei , Zhou Zhengxian , Qin Zhengbo , Zheng Xianfeng
Published: January 2024

A simple and convenient method has been developed to improve the LIBS detection performance of a liquid aerosol by adjusting the liquid aerosol temperature.
Development and future of droplet microfluidics
Authors: Nan Lang , Zhang Huidan , Weitz David A. , Shum Ho Cheung
Published: January 2024

This review introduces the development of droplet microfluidics by explaining the physical mechanisms of droplet generation, discussing various approaches in manipulating droplets, and summarizing key applications in material science and biological analyses.
Microfluidic synthesis of radiotracers: recent developments and commercialization prospects
Authors: Mc Veigh Mark , Bellan Leon M.
Published: January 2024

Current radiotracer production approaches restrict clinicians' access to a wide range of targeted probes. In this review, we assess the current state of microfluidic synthesis platforms with a view towards future dose-on-demand production.
Microfluidic synthesis of lipid-based nanoparticles for drug delivery: recent advances and opportunities
Authors: Mehraji Sima , DeVoe Don L.
Published: January 2024

The current landscape of microfluidic technologies for lipid nanoparticle production, size control, scaling, and nanomedicine post-processing is described in a review of this evolving field.
A photoarchitectonic hydrogel for synergistic in vitro chemo–phototherapy of breast cancer
Authors: Paul Shatabdi , Yadav Binduma , Patil Mahesh D. , Pujari Anil Kumar , Singh Umesh , Rishi Vikas , Bhaumik Jayeeta
Published: January 2024

Laser-assisted combinatorial breast cancer treatment using a photoarchitectonic hydrogel shows a synergistic effect.
Recent advances in metal–organic frameworks for lubrication
Authors: Wang Chenxia , Zhou Mingan , Cao Hao , Lin Hualin , Han Sheng
Published: January 2024

In recent years, metal–organic frameworks (MOFs) have attracted much attention in lubrication due to their unique structures.
Simultaneous optimisation of shape and magnetisation of nanoparticles synthesised using a green bioinspired route
Authors: Norfolk Laura , Dewulf Luc , Chiacchia Mauro , Patwardhan Siddharth V. , Staniland Sarah S.
Published: January 2024

A novel DoE strategy enabled the optimisation of two responses simultaneously to produce high quality magnetic nanoparticles under environmentally friendly conditions.
The preparation and performance evaluation of flame-retardant antistatic composites based on polyurethane
Authors: Zhan Zhaoshun , Shi Qixing , Wang Lei , Shen Jinfeng , Bao Tianyou , Li Lixin , Meng Fanna
Published: January 2024

A novel dual-functional DMM@NC with flame retardancy and antistatic properties was synthesized and introduced into RPUF to improve the safety of polyurethane in coal mines.
Photo-induced C(sp2)–H difluoroalkylation of anilines
Authors: Zhu Xing-Li , Wang Hua , Zhai Chen-Kai , He Wei
Published: January 2024

Light-promoted direct aromatic C–H difluroalkylation of aniline derivatives with bromodifluoro esters and amides has been disclosed. This reaction operates under catalyst-free conditions and features a broad substrate scope.
TiCl4-mediated deoxygenative reduction of aromatic ketones to alkylarenes with ammonia borane
Authors: Zang Yongjun , Ma Yunfeng , Xu Qilin , Li Guosi , Chen Naidong , Li Xing , Zhu Fucheng
Published: January 2024

A rapid and mild protocol for the exhaustive deoxygenation of various aromatic ketones to corresponding alkanes using AB as a reductant and TiCl4 as a catalyst.
Polyoxometalate-based frameworks as chemical nanoreactors: in situ synthesis of active silver nanoparticles in confined spaces
Authors: Zeng Hui-Min , Wang Xiao-Juan , Jiang Zhan-Guo , Zhan Cai-Hong
Published: January 2024

A novel strategy for the synthesis of Ag@POMOF, that is, well-sized silver nanoparticles confined in a POMOF, has been demonstrated through in situ assembly of silver ions with {Mo36} ions along with reduction.
Nickel/photoredox dual-catalyzed reductive cross-coupling of aryl halides and aldehydes
Authors: Liu Junjie , Chen Yukun , Zhao Hongping , Yuan Weiming
Published: January 2024

A photoredox-assisted nickel-catalyzed reductive coupling of aryl halides and aldehydes to afford silyl-protected alcohols is reported. Key to success of this strategy is to identify α-silylamines as efficient organic reductants.
Distribution and toxicity of dihydroxybenzenes in drinking water sources in Nigeria
Authors: Otitoju Oluwaferanmi B. , Alfred Moses O. , Olorunnisola Chidinma G. , Aderinola Francis T. , Ogunlaja Olumuyiwa O. , Olukanni Olumide D. , Ogunlaja Aemere , Omorogie Martins O. , Unuabonah Emmanuel I.
Published: January 2024

This study provides, for the first time, data on the distribution and toxicity of catechol (CAT) and hydroquinone (HQ) in drinking water sources from Africa.
Poly-beta-amino-ester licofelone conjugates development for osteoarthritis treatment
Authors: Alghamdi Raed , Pertusati Fabrizio , Prokopovich Polina
Published: January 2024

Disease-modifying osteoarthritis drugs (DMOADs) are a new therapeutic class for osteoarthritis (OA) prevention or inhibition of the disease development.
Sodium alginate/carboxymethyl cellulose films embedded with liposomes encapsulated green tea extract: characterization, controlled release, application
Authors: Feng Xin , Li Yang , Cui Zhuoyu , Tang Rongrong
Published: January 2024

To maintain the freshness of the fruit during storage, sodium alginate/carboxymethyl cellulose films embedded with pH-senstive liposomes encapsulated green tea extract were developed (SA/CMC/TP-Lip).
Study on dechlorination salt characteristics of pickling sludge by a water-washing process
Authors: Xu Yane , Xu Likui , Yuan Jie , Luo Hongchao , Yin Chaochuang , Lei Yizhu , Lian Guoqi , Ma Aiyuan , Shu Xinqian
Published: January 2024

Dechlorination of SHPS by water washing was investigated. Approximately 96–99% of Cl and Na can be removed by water washing. The Fe, Zn, Mn, Ni and other elements are enriched in the FR.
Enhanced catalytic reductive hydrogenation of an organic dye by Ag decorated graphitic carbon nitride modified MCM-41
Authors: Pradhan Manas Ranjan , Nanda Braja B. , Subhadarshini Asima , Panda Lipsa , Nanda Binita
Published: January 2024

Graphical representation of the decolorization of RhB to its leuco form using Ag nanoparticle-modified gCN/MCM-41.
Green synthesized gold nanoparticles and CuO-based nonenzymatic sensor for saliva glucose monitoring
Authors: Ali Md Younus , Abdulrahman Heman B. , Ting Wei-Ting , Howlader Matiar M. R.
Published: January 2024

Gold nanoparticles (AuNPs) were synthesized using HAuCl4 and orange peel extract. AuNPs and CuO modified screen printed carbon electrode (Au/CuO/SPCE) converts glucose to gluconolactone. This sensor was applied for detection of glucose in saliva.
Hemostatic and antibacterial calcium–copper zeolite gauze for infected wound healing
Authors: Wang Mingtao , Zhang Wenzhao , Wang Chenchen , Xiao Liping , Yu Lisha , Fan Jie
Published: January 2024

A calcium–copper zeolite gauze exhibits remarkable procoagulant and antibacterial ability, as well as good biocompatibility. The remarkable ability of wound healing has been verified using a mouse dorsal skin-infected wound model.
Synthesis of CoFe2O4@SiO2–NH2 and its application in adsorption of trace lead
Authors: Zeng Yanxia , Xie Jiliang , Xiao Xin , Chen Li , Zhu Xiashi
Published: January 2024

In this work, an amine functionalized CoFe2O4 magnetic nanocomposite material was prepared and is shown to be an efficient adsorbent for the separation and analysis of trace lead in water.
A comprehensive review of synthesis kinetics and formation mechanism of geopolymers
Authors: Siyal Ahmer Ali , Radin Mohamed Radin Maya Saphira , Shamsuddin Rashid , Ridzuan Mohd Baharudin
Published: January 2024

This paper reviews synthesis kinetics and formation mechanism of geopolymers. The literature studies provided new information, and development of advanced techniques is required to study synthesis kinetics and formation mechanisms further.
High-throughput light sheet imaging of adult and larval C. elegans Parkinson's disease model using a low-cost optofluidic device and a fluorescent microscope
Authors: Rahimpouresfahani Faraz , Tabatabaei Nima , Rezai Pouya
Published: January 2024

We report a simple and low-cost optofluidic platform that can be added to conventional microscopes for continuous light-sheet imaging of C. elegans populations at L3 and YA stages.
Recent advances in the synthesis and utility of thiazoline and its derivatives
Authors: Kumar Sumit , Arora Aditi , Sapra Shivani , Kumar Rajesh , Singh Brajendra K. , Singh Sunil K.
Published: January 2024

Thiazolines and their derivatives hold significant importance in the field of medicinal chemistry due to their promising potential as pharmaceutical agents.
Advances in the characterisation and identification of mastic (Pistaciasp.) resin in archaeological samples by GC-QToF-MS
Authors: Tamburini Diego , Fulcher Kate , Briggs Lisa , von Aderkas Nelly , Pulak Cemal , Stacey Rebecca
Published: January 2024

A new analytical method based on GC-QToF-MS is proposed for the enhanced characterisation and identification of mastic (Pistaciasp.) resin in archaeological samples. New insights into the use of mastic in ancient Egypt are provided.
Preparation of multifunctional ceramic foams for sound absorption, waterproofing, and antibacterial applications
Authors: Zhang Xizhi , Chen Xiaozhong , Min Wenchao , Liang Guowei , Zhang Wei , Yao Shuheng , Zhong Ximing
Published: January 2024

This work provides a facile strategy to develop a multifunctional ceramic system, and the resultant ceramic foams can be used for sound-absorbing, waterproof, and antibacterial applications.
Successful removal of fluoride from aqueous environment using Al(OH)3@AC: column studies and breakthrough curve modeling
Authors: Bakhta S. , Sadaoui Z. , Bouazizi N. , Samir B. , Cosme J. , Allalou O. , Le Derf F. , Vieillard J.
Published: January 2024

The successful removal of fluoride from water in dynamic mode with an innovative material was achieved. The maximum adsorption capacity in the column was 41.84 mg g−1 at 7.5 mL min−1.
Photo-responsive nanoporous liquid crystal polymer films for selective dye adsorption
Authors: Zeng Hongju , Wang Yun , Li Changxiang , Ren Junjie , Lu Runzi , Zhang Huiyao , Wang Xi , Lv Xingbin , Yu Hairong , Liang Ting , Cheng Changjing
Published: January 2024

A photo-responsive nanoporous polymer film (AZOF-R(NC6)) has been fabricated. AZOF-R(NC6) shows charge-selective and light-responsive dye adsorption.
Interpretation of the adsorption process of toxic Cd2+ removal by modified sweet potato residue
Authors: Gao Yu , Yi Zhuolin , Wang Jinling , Ding Fan , Fang Yang , Du Anping , Jiang Yijia , Zhao Hai , Jin Yanling
Published: January 2024

Sweet potato residue modified by NaOH removed Cd2+ by complexation, ion exchange, and precipitate during a monolayer chemisorption adsorption process.
The effects of partially or fully linked boron with a cross-linking structure of an organic precursor on the purity and morphology of ZrB2 powder
Authors: Yang Xi , Han Weijian , Zhao Tong , Li Ruixing
Published: January 2024

Partially or fully linked boron with a cross-linking structure of an organic precursor affects the purity and morphology of ZrB2 powder.
Portable glucose sensing analysis based on laser-induced graphene composite electrode
Authors: Zhang Zhaokang , Huang Lu , Chen Yiting , Qiu Zhenli , Meng Xiangying , Li Yanxia
Published: January 2024

In this work, a portable electrochemical glucose sensor was studied based on a laser-induced graphene (LIG)/PEDOT/Au/GOx micro-sensing interface.
Hierarchical porous carbon aerogels as a versatile electrode material for high-stability supercapacitors
Authors: Yang Kai , Fan Qingwen , Zhang Yuchun , Ren Gangxin , Huang Xinfeng , Fu Peng
Published: January 2024

Carbon aerogels with 3D hierarchical porous structure were successfully fabricated. CA-AA exhibited 138 F g−1 at 1 A g−1 superior to cellulose-based active carbon. During 5000 cycles at 1 A g−1, the capacitance retention ratio of CA-AA exceeds 100%.
New adsorbent materials based on PILs for Freon refrigerants
Authors: Xin Mingyuan , Wang Qiang , Wang Qiang , Wang Haoyu , Muhammad Furqan , Nie Guanze
Published: January 2024

The development of refrigerant adsorbent materials is not only essential for enhancing the efficiency of refrigeration systems but also plays a pivotal role in environmental conservation and addressing global warming challenges.
Design, synthesis, pharmacological evaluation, and in silico studies of the activity of novel spiro pyrrolo[3,4-d]pyrimidine derivatives
Authors: Alzahrani Abdullah Y. A. , Shehab Wesam S. , Amer Asmaa H. , Assy Mohamed G. , Mouneir Samar M. , Abdelaziz Maged , Abdel Hamid Atef M.
Published: January 2024

In the present study, spiro compounds are shown to have distinctive characteristics because of their interesting conformations and their structural impacts on biological systems.
Development of a green, concise synthesis of nicotinamide derivatives catalysed by Novozym® 435 from Candida antarctica in sustainable continuous-flow microreactors
Authors: Sheng Zhi-Kai , Liu Yi , Du Li-Hua , Zhang Shi-Yi , Zhang Ao-Ying , Xie Han-Jia , Lin Hang , Yan Bing-Lin , Xue Miao-Miao , Ruan Zhi-Xuan , Fu Guo-Neng , Pan Bing-Le , Zhou Tong-Yao , Luo Xi-Ping
Published: January 2024

A continuous production of nicotinamide derivatives was performed for the first time by exploiting the continuous-flow microreactors coupled with enzymes.
Electrochemical oxidative cyclization of N-allylamides for the synthesis of CF3-containing benzoxazines and oxazolines
Authors: Li Yutian , Wang Li , Zhou Shengbin , He Guoxue , Zhou Yu
Published: January 2024

A facile electrochemical oxidative and radical cascade cyclization of N-(2-vinylphenyl)amides with CF3SO2Na was conducted to synthesize the CF3-containing benzoxazines and oxazolines.
Photoluminescence switching in quantum dots connected with fluorinated and hydrogenated photochromic molecules
Authors: Sarabamoun Ephraiem S. , Bietsch Jonathan M. , Aryal Pramod , Reid Amelia G. , Curran Maurice , Johnson Grayson , Tsai Esther H. R. , Machan Charles W. , Wang Guijun , Choi Joshua J.
Published: January 2024

We investigate switching of photoluminescence from PbS quantum dots crosslinked with photochromic diarylethene molecules with different degree of halogenation.
Component-controlled synthesis of PdxSny nanocrystals on carbon nanotubes as advanced electrocatalysts for oxygen reduction reaction
Authors: Guo Weibin , Yang Rui , Fan Jiayao , Xiang Xing , Du Xuehui , Shi Naien , Bao Jianchun , Han Min
Published: January 2024

A series of PdxSny nanocrystals loaded on carbon nanotubes (CNTs) nanohybrids have been synthesized. Due to the proper alloy constituent and the strong interplay between the two components, the resultant Pd3Sn/CNTs exhibit excellent ORR activity.
Recent advances in the application of alkynes in multicomponent reactions
Authors: Hosseininezhad Seyedmohammad , Ramazani Ali
Published: January 2024

The reactions and mechanisms of alkynes that are involved in multi-component reactions through C–C and C–H positions are investigated.
Construction and characterization of a magnetic nanoparticle-supported Cu complex: a stable and active nanocatalyst for synthesis of heteroaryl-aryl and di-heteroaryl sulfides
Authors: Fang Yutong , Chen Songlin , Chang Li-Yuan
Published: January 2024

Growing demand for eco-friendly catalysts in drug synthesis. Fe3O4@AMBA-CuI nanomaterials, a reusable catalyst, enable synthesis of diaryl and di-heteroaryl sulfides from diverse substrates. Reusability tests confirm stability, maintaining magnetic properties through six uses, yielding sulfides.
Photocatalytic selective synthesis of (E)-β-aminovinyl sulfones and (E)-β-amidovinyl sulfones using Ru(bpy)3Cl2 as the catalyst
Authors: Huang Yu-Wen , Li Jia-Zhuo , Yang Feng , Zhang Xi-Yu , Wang Yan-Jing , Meng Xin-Chao , Leng Bo-Rong , Wang De-Cai , Zhu Yi-Long
Published: January 2024

A photocatalytic strategy has been developed for the selective synthesis of (E)-β-aminovinyl sulfones and (E)-β-amidovinyl sulfones through the utilization of allenamides and sodium sulfinates.
Urea-rich porous organic polymer as a hydrogen bond catalyst for Knoevenagel condensation reaction and synthesis of 2,3-dihydroquinazolin-4(1H)-ones
Authors: Zarei Narges , Yarie Meysam , Torabi Morteza , Zolfigol Mohammad Ali
Published: January 2024

General procedure for the catalytic synthesis of Knoevenagel adducts and 2,3-dihydroquinazolin-4(1H)-ones.
Direct synthesis of spirobifluorenes by formal dehydrative coupling of biaryls and fluorenones
Authors: Kato Yugo , Nishimura Kazutoshi , Nishii Yuji , Hirano Koji
Published: January 2024

A dehydrative coupling of biaryls and fluorenones proceeds under TfOH- or Tf2O-promoted conditions to deliver the corresponding SBFs directly. This protocol is applicable to double cyclisation, giving the SBF-based highly π-conjugated molecules.
Measuring metal halide perovskite single cell degradation consistent with module-based conditions
Authors: Tirawat Robert , Louks Amy E. , Yang Mengjin , Habisreutinger Severin N. , van de Lagemaat Jao , Uličná Soňa , Kerner Ross A. , Zhu Kai , Schelhas Laura T. , Palmstrom Axel F. , Berry Joseph J.
Published: January 2024

Although a harsher condition, degradation of perovskite solar cells in an open-circuit condition is related to the performance in a quasi-maximum power point condition. Further, shadow masks should be used during illuminated stability studies.
Experimental discovery of novel ammonia synthesis catalysts via active learning
Authors: Jayarathna Rasika , Onsree Thossaporn , Drummond Samuel , Naglic Jennifer , Lauterbach Jochen
Published: January 2024

Active learning based on literature and experimental data enabled the discovery of highly active novel catalysts for ammonia synthesis. Pathway analysis implies that these activities have been achieved by both structural and electronic promotion.
Durable and recyclable biomimetic glycol lignin/polyolefin compounds for a circular economy
Authors: Tanks Jonathon , Tamura Kenji , Naito Kimiyoshi , Nge Thi Thi , Yamada Tatsuhiko
Published: January 2024

Glycol lignin acts as a simultaneous UV absorbent, antioxidant, and mechanical reinforcement in polyolefins, thereby reducing carbon emissions and facilitating effective mechanical recycling.
Regulating the thermoelectric power factor of donor–acceptor copolymers by heavy chalcogen substitution: a first-principles study
Authors: Wang Yishan , Wei Yu , Hao Wei , Li Hanying , Li Shuzhou , Zhu Jia , Fang Weihai
Published: January 2024

Te substitution of sulfur (S) in PzDPP-based donor–acceptor copolymers enhances n-type power factor, while Se boosts both n-type and p-type power factors. Heavy chalcogen doping strategy shows promise for improving thermoelectric properties.
Advancements in MXene-based composites for electronic skins
Authors: Iravani Siavash , Rabiee Navid , Makvandi Pooyan
Published: January 2024

Recent advancements, important challenges, advantages, and future prospects of MXenes and their composites in E-skins are deliberated.
Effect of zwitterionic sulfobetaine incorporation on blood behaviours, phagocytosis, and in vivo biodistribution of pH-responsive micelles with positive charges
Authors: Wang Chengwei , Liu Hao , Lin Hu , Zhong Rui , Li Hao , Liu Jiaxin , Luo Xianglin , Tian Meng
Published: January 2024

A series of pH-responsive and sulfobetaine-incorporated micelles with positive charges is prepared, in which the effects of the sulfobetaine incorporation displayed different profiles in the blood behaviours, phagocytosis, and in vivo biodistribution.
A potent multifunctional ZIF-8 nanoplatform developed for colorectal cancer therapy by triple-delivery of chemo/radio/targeted therapy agents
Authors: Iranpour Sonia , Bahrami Ahmad Reza , Dayyani Mahdieh , Saljooghi Amir Sh. , Matin Maryam M.
Published: January 2024

Background: Multimodal cancer therapy has garnered significant interest due to its ability to target tumor cells from various perspectives.
Copper(ii)-infused porphyrin MOF: maximum scavenging GSH for enhanced photodynamic disruption of bacterial biofilm
Authors: Zhang Yaoxin , Li Linpei , Liu Hui , Zhang Haixia , Wei Menghao , Zhang Junqing , Yang Yanwei , Wu Mengnan , Chen Zhaowei , Liu Chaoqun , Wang Faming , Wu Qiang , Shi Jiahua
Published: January 2024

A maximum GSH-depleting photodynamic nanosystem was developed by loading Cu2+ into porphyrin MOF. Both in vitro and in vivo results indicate MOF@Cu2+ could obliterate biofilm infection and facilitate wound healing with no distinct side effects.
Electrogelated drug-embedded silk/gelatin/rGO degradable electrode for anti-inflammatory applications in brain-implant systems
Authors: Lin Zhen-Kai , Lin Jing-Syu , Chen Zih-Huei , Cheng Hung-Wei , Huang Wei-Chen , Chen San-Yuan
Published: January 2024

A degradable electrogel drug-embedded silk/gelatin/rGO/DEX composite implanted electrode showed tunable mechanical properties and electro-stimulated drug release to interrupt astrocyte growth and reduce inflammatory response for utilization in neural interfaces.
Correction: Enhanced DNA release from disulfide-containing layered nanocomplexes by heparin-electrostatic competition
Authors: Chen Zhenzhen , He Yuling , Zhang Lifen , Li Yanfeng
Published: January 2024

Correction for ‘Enhanced DNA release from disulfide-containing layered nanocomplexes by heparin-electrostatic competition’ by Zhenzhen Chen et al., J. Mater. Chem. B, 2015, 3, 225–237, https://doi.org/10.1039/c4tb01113a.
Revealing two chemical strategies to tune bright one- and two-photon excited fluorescence of carbon nanodots
Authors: Mucha Sebastian G. , Firlej Lucyna , Formalik Filip , Bantignies Jean-Louis , Anglaret Eric , Samoć Marek , Matczyszyn Katarzyna
Published: January 2024

The internal structure (oxygenous groups and conjugated aromatic domains) and the hydrogen-bonding network with solvent molecules are two ways to tune the fluorescence of carbon nanodots upon one- and two-photon excitation.
Glue-like passivation by the natural alkene lycopene for efficient and stable perovskite solar cells: insights from a theoretical perspective
Authors: Chen Na , Li Quan-Song
Published: January 2024

Conjugated CC bonds of alkene achieve robust interaction in cover style, which is beneficial for stability and ion migration in long-term and efficient perovskite solar cells.
Realizing high zero-bias gain in a GaN-based bipolar phototransistor through thin-base configuration for ultraviolet imaging
Authors: Wang Bingxiang , Jiang Ke , Zhang Shanli , Chen Yuxuan , Fang Tong , Xie Zhiwei , Ben Jianwei , Chen Yang , Jia Yuping , Liu Mingrui , Sun Xiaojuan , Li Dabing
Published: January 2024

A GaN-based ultraviolet bipolar phototransistor with high zero-bias gain is obtained based on an asymmetric n–p–i–n homo-structure. A thin-base structure is proposed to suppress excess holes recombination and, thus, to promote optical gain.
An ambient process for hole transport layer-free highly stable MAPbI3 by addition of MACl for efficient perovskite solar cells
Authors: Nandigana Pardhasaradhi , Saminathan Bavatharini , P. Sriram , D. Sujatha , M. Imthiaz Ahmed , R. Ram Prasanth , Subramanian B. , Panda Subhendu K.
Published: January 2024

An ambient process for the fabrication of HTL-free carbon-based perovskite solar cells at room temperature with the addition of an optimized amount of MACl into the perovskite precursor solution.
The consequence of ATP synthase dimer angle on mitochondrial morphology studied by cryo-electron tomography
Authors: Buzzard Emma , McLaren Mathew , Bragoszewski Piotr , Brancaccio Andrea , Ford Holly C. , Daum Bertram , Kuwabara Patricia , Collinson Ian , Gold Vicki A.M.
Published: January 2024

Mitochondrial ATP synthases form rows of dimers, which induce membrane curvature to give cristae their characteristic lamellar or tubular morphology. The angle formed between the central stalks of ATP synthase dimers varies between species. Using cryo-electron tomography and sub-tomogram averaging, we determined the structure of the ATP synthase dimer from the nematode worm Caenorhabditis elegans and show that the dimer angle differs from previously determined structures. The consequences of this species-specific difference at the dimer interface were investigated by comparing C. elegans and Saccharomyces cerevisiae mitochondrial morphology. We reveal that C. elegans has a larger ATP synthase dimer angle with more lamellar (flatter) cristae when compared with yeast. The underlying cause of this difference was investigated by generating an atomic model of the C. elegans ATP synthase dimer by homology modelling. A comparison of our C. elegans model to an existing S. cerevisiae structure reveals the presence of extensions and rearrangements in C. elegans subunits associated with maintaining the dimer interface. We speculate that increasing dimer angles could provide an advantage for species that inhabit variable-oxygen environments by forming flatter, more energetically efficient cristae.
Naturalistic Developmental Behavioral Interventions for Developmental Language Disorder
Authors: Camarata Stephen , Stiles Suzanne , Birer Samara
Published: January 2024

Purpose:

Naturalistic–developmental–behavioral interventions (NDBIs) are a widely accepted and validated approach for treating language-related symptoms in autism spectrum disorder, including deficits in vocabulary, social skills, and grammar. The purpose of this article is to define the elements
naturalistic
,
developmental
, and
behavioral
as applied to children with developmental language disorder (DLD) and to provide an example of how this type of intervention can be implemented to teach vocabulary and test cross-modal generalization between expressive and receptive modalities.

Method:

A vocabulary intervention using hybrid NDBI methods (storybook reading and conversational recast interaction) was provided to three participants with DLD using a single-case design.

Results:

The results indicated that all participants successfully learned receptive and expressive vocabulary targets with extensive cross-modal generalization. However, generalization was limited in some of the participants.

Conclusions:

This article provided definitions of key elements of NDBI (
naturalistic
,
developmental
, and
behavioral
) including a rationale for extending NDBI procedures to language intervention for children with DLD. In addition, a single-case design demonstrated that NDBI can be implemented in DLD and that broadly defined naturalistic–developmental applied behavior analysis techniques are applicable to language interventions for children with language disorders. Moreover, diverse
naturalistic
and
developmental
procedures meet the highest standards for evidence-based practice to treat DLD.
Der Ski-Daumen
Authors: Meyer Nora , Meißner Elisabeth
Published: January 2024

Präzises Schreiben mit einem Stift, einen Faden in das Nadelöhr
einfädeln, Werkzeuge kraftvoll greifen und bedienen oder feine
Oberflächen und Texturen erfühlen – das alles
wäre ohne unsere Daumen undenkbar. Durch die Gegenüberstellung
zu den Langfingern hat der Daumen eine besondere Funktion. Um ihn im Alltag
erfolgreich nutzen zu können, sind seine stabilisierenden Strukturen
besonders wichtig. Wird das Daumengrundgelenk instabil, sind schmerzhafte und
stark beeinträchtigte Greiffunktionen die Folge.
Evaluation einer eHealth-Intervention zur Tabakentwöhnung
– eine qualitative Analyse zu Zufriedenheit und
Nutzereindrücken
Authors: Maiwald Phillip , Lindinger Peter , Tinsel Iris , Fichtner Urs , Farin-Glattacker Erik , Bischoff Martina
Published: January 2024

Ziel der Studie  In Deutschland besteht ein Bedarf an
Interventionen zur Tabakentwöhnung, die niedrigschwellig
verfügbar sind. Eine Lösung hierfür sind
eHealth-Angebote; Forschung zu Benutzereindrücken und -zufriedenheit
hinsichtlich dieser Interventionen ist allerdings selten. Die vorliegende Studie
gewinnt detaillierte Erkenntnisse im Hinblick auf die Nutzererfahrungen von
Raucher*innen mit dem onlinebasierten
„TK-NichtraucherCoaching“.
Methodik  15
Nutzer*innen eines onlinebasierten, individualisierbaren und
interaktiven Nichtraucher-Coachings nahmen an semistrukturierten
Telefoninterviews teil. Die Gespräche wurden zur Erstellung eines
Codesystems mittels einer deduktiv-induktiven qualitativen Inhaltsanalyse nach
Kuckartz ausgewertet.
Ergebnisse  Es wurden 20
Hauptkategorien, 51 Subkategorien und 13 Sub-Subkategorien gebildet. Das finale
Codesystem umfasste 199 positiv und 90 negativ bewertende Aussagen. Besonders
die emotionale Unterstützung und die Motivierung durch das Programm, die
Niederschwelligkeit des Angebots, die optische Gestaltung, die Inhalte der
Vorbereitungsphase sowie die Erfolgsübersicht der zweiten Programmphase
wurden von den Nutzer*innen gelobt. Gemischte Ergebnisse ergaben sich
bezüglich der Individualisierungsmöglichkeiten des Programms,
der Nützlichkeit und des Umfangs der vermittelten Informationen, der
Unterstützung bei Entzugssymptomen und Rückfällen, der
Bedienung und der technischen Umsetzung sowie der optionalen telefonischen
Beratung.
Schlussfolgerung  Digitale Angebote
können einer großen Zahl von Raucher*innen einen
niederschwelligen Zugang zu Interventionen zur Tabakentwöhnung
ermöglichen. Die hier untersuchte Intervention wurde überwiegend
positiv bewertet. Durch die Erstellung eines ausführlichen Codesystems
wurden umfassende Einblicke hinsichtlich Nutzereindrücken und
Zufriedenheit der Teilnehmer*innen ermöglicht. Darauf basierend
konnten zahlreiche Optimierungsmöglichkeiten für ein solches
Angebot erarbeitet werden. Beispiele hierfür sind eine
Überarbeitung der Menüführung, eine Flexibilisierung des
Ablaufs, eine Umsetzung als Smartphone-App sowie die Bereitstellung von
textbasierten Chats.
Prädiktoren der Erledigung bei nach §64 StGB
untergebrachten Patienten – Ein Literaturreview
Authors: Scheuschner Lene , Walde Peggy , Völlm Birgit
Published: January 2024

Hintergrund Bei nach §64 StGB untergebrachten suchtkranken
Straftätern kann die Unterbringung vorzeitig beendet werden. Es liegt
eine umfangreiche Literatur zu Prädiktoren einer vorzeitigen Beendigung
vor Therapiebeginn vor.

Zielsetzung Ziel dieser Arbeit ist es, Prädiktoren einer
vorzeitigen Erledigung während des Therapieverlaufs darzustellen.

Methodik Es wurde eine systematische Literaturrecherche
durchgeführt und 16 Publikationen eingeschlossen.

Ergebnisse Sowohl Patienten als auch Therapeuten sehen vor allem
Impulsivität/Aggressivität,
Suchtmittelrückfälle und eine mangelnde
Patient-Therapeuten-Beziehung als negative Prädiktoren. Beide Gruppen
schreiben dem Vorhandensein von Motivation und einem positiven sozialen Netzwerk
förderlichen Einfluss auf das Outcome zu.

Schlussfolgerung Für ein erfolgreiches Beenden der Unterbringung
sind eine tragfähige Patienten-Therapeuten-Beziehung, Motivationsarbeit
und das Aufarbeiten von Vorfällen essentiell.
Freizeitdrogenkonsum und Drug Checking
Authors: Schori Dominique
Published: January 2024

Drug Checking ist ein Angebot der Schadensminderung und richtet sich
hauptsächlich an Freizeitdrogenkonsumierende. Im Zentrum des Angebots
steht die Vermittlung von Konsumkompetenz sowie die Sensibilisierung für
Konsumrisiken, basierend auf laboranalytischen Fakten. Drug-Checking-Angebote
gibt in wachsender Zahl in verschiedenen europäischen Städten.
Die politische Akzeptanz für Drug Checking als Instrument der
Schadensminderung steigt, zunehmend rückt aber auch die Bedeutung von
Drug Checking zum Monitoring des illegalen Drogenmarktes in den Fokus.
Drug-Checking-Angebote müssen sich kontinuierlich an den sich
ändernden Konsum- und Marktrealitäten anpassen und spielen eine
zentrale Rolle bei der Diskussion rund um die Regulierung von illegalen
Substanzen (z. B. Cannabis).
Good Outcome of Resective Epilepsy Surgery in a 1-Year-Old Child with Drug-Resistant Focal Epilepsy with a Novel Pathogenic COL4A1 Mutation
Authors: Fearns Nicholas , Wagner Matias , Borggräfe Ingo , Kunz Mathias , Rémi Jan , Vollmar Christian
Published: January 2024

Pathogenic variants in COL4A1, encoding the α chain of type IV collagen, have been associated with cerebrovascular pathology as well as malformations of cortical development, thereby causing structural epilepsy. This case illustrates successful resective epilepsy surgery in a 12-month-old girl with left occipital focal cortical dysplasia (FCD) associated with a heterozygous splice-donor variant in COL4A1. She presented with drug-resistant focal epilepsy with daily seizures from the age of 2 months, refractory to several combinations of antiseizure medications, as well as mild right-sided hemiparesis and developmental delay. All presurgical diagnostic modalities, including ictal and interictal electroencephalography, magnetic resonance imaging, and ictal fluorodeoxyglucose positron emission tomography, showed congruent findings, pointing toward one single left occipital epileptogenic zone (EZ). We performed a left occipital lobectomy, using intraoperative electrocorticography to confirm the boundaries of the EZ. After surgery, the patient has remained seizure free, and both cognitive and motor developments have improved. Histopathology of the resected brain tissue showed FCD type Ia. Resective epilepsy surgery can have a very good outcome, also in patients with genetic mutations in COL4A1, constituting a less invasive option than the previously used more radical surgical procedures such as hemispherectomy.