bluuebunny/crossref_metadata_2025 huggingface dataset:
Theoretical foundations, computational methods, and practical applications of nondeterministic fuzzy abstraction
Authors: Deng Hui
Published: August 2023

Efficient and effective modeling of complex real-world situations characterized by uncertainty poses a substantial challenge. This study addresses this challenge by introducing a nondeterministic fuzzy abstraction approach to enhance efficiency and effectiveness in this context. The theoretical framework establishes a standardized representation of nondeterministic fuzzy Kripke structures, accompanied by definitions associated with nondeterministic fuzzy abstraction. The methods section presents an algorithm for realizing nondeterministic fuzzy abstraction, and it is well-suited for practical implementation in computer programs. The results section demonstrates the practical application of the proposed approach by modeling the process of treating a patient with ulcers in the terminal ileum. In the discussion section, a comparative study of nondeterministic fuzzy abstraction underscores its broad applicability and compatibility across various uncertainty and certainty model structures.
Natural Fracture Propagation Analysis of the
Silurian (Llandovery) Hot Shales of the Northern Arabian Plate
Authors: Sen Samil
Published: August 2023

The Silurian (Llandovery) hot shales of the northern Arabian Plate exhibit three main sets of fractures consisting of vertical-high angle to bedding, low angle to bedding, and bedding parallel fractures. The fractures are generally open, except for the vertical-high angle to bedding fractures and "beef" fractures. The fracture intensity ranges from low to high, and the shales are rich in clay and carbonates based on a ternary diagram analysis. The mineral-based brittleness index (MBI) values of the hot shales vary from 0.24 to 0.91, with an average of 0.59. Mechanical anisotropy analysis shows that Point Load IS(50) values range from 0.25 to 1.68 MPa in the bedding-parallel direction and from 2.05 to 2.46 MPa in the vertical to bedding direction. The natural fracture propagation of the hot shales is controlled by regional tectonic events, mechanical anisotropy, natural hydraulic overpressure driven by hydrocarbon maturation, and MBI values. The vertical-high angle to bedding fractures are believed to have been formed by the extensional tectonic activity associated with the opening of the Neotethys Ocean. The low angle to bedding and bedding parallel fractures are attributed to thrust tectonic activity of the Bitlis Nappes, mechanical anisotropy of laminations, and natural hydraulic overpressures caused by hydrocarbon maturation.
Genome sequence and assembly of the amylolytic Bacillus licheniformis T5 strain isolated from Kazakhstan soil
Authors: Mussakhmetov Arman , Kiribayeva Assel , Daniyarov Asset , Bulashev Aitbai , Kairov Ulykbek , Khassenov Bekbolat
Published: August 2023

Objectives:
The data presented in this study were collected with the aim of obtaining the complete genomes of specific strains of Bacillus bacteria, namely, Bacillus licheniformis T5. This strain was chosen based on its enzymatic activities, particularly amylolytic activity. In this study, nanopore sequencing technology was employed to obtain the genome sequences of this strain. It is important to note that these data represent a focused objective within a larger research context, which involves exploring the biochemical features of promising Bacilli strains and investigating the relationship between enzymatic activity, phenotypic features, and the microorganism's genome.
Data description:
In this study, the whole-genome sequence was obtained from one Bacillus strain, Bacillus licheniformis T5, isolated from soil samples in Kazakhstan. This sequence encompasses the complete genetic information of the strain, including genes, regulatory elements, and noncoding regions. The data reveal important insights into the genetic characteristics, phenotypic traits, and enzymatic activity of this Bacillusstrain.
The findings of this study have particular value to researchers interested in microbial biology, biotechnology, and antimicrobial studies. The genomic sequence offers a foundation for understanding the genetic basis of traits such as endospore formation, alkaline tolerance, temperature range for growth, nutrient utilization, and enzymatic activities. These insights can contribute to the development of novel biotechnological applications, such as the production of enzymes for industrial purposes.
Overall, this study provides valuable insights into the genetic characteristics, phenotypic traits, and enzymatic activities of the Bacillus licheniformis T5 strain. The acquired genomic sequences contribute to a better understanding of this strain and have implications for various research fields, such as microbiology, biotechnology, and antimicrobial studies.
MOF-modulated Fe3O4 Composited Au Nanoparticles for Antibacterial Wound Healing via Synergistic POD-like Nanozymatic Catalysis
Authors: Liu Chuan , Zhao Xuanping , Wang Zichao , Zhao Yingyuan , Li Ruifang , Chen Xuyang , Chen Hong , Wan Mengna , Wang Xueqin
Published: August 2023

Bacterial-induced wound infection and healing difficulty severely threat people’s health and lives nowadays. Although traditional antibiotic treatment provides an effective strategy to defeat pathogenic bacteria, prolonged use and overuse of antibiotics cause the bacterium evolution with antibiotic resistance. Herein, we report an innovative hybrid nanozyme independent of antibiotics used for antimicrobial wound healing, which is constructed with ultrasmall Au NPs via in-situ growth on metal-organic framework (MOF) stabilized Fe3O4NPs (Fe3O4@MOF@Au NPs, FMA NPs). The results showed that the fabricated hybrid nanozyme displayed synergistic peroxidase (POD)-like activities, and generated a remarkable level of hydroxyl radicals (·OH) when assisted with a low dose of H2O2. Furthermore, the results showed that the hybrid FMA nanozymes exhibited excellent biocompatibility and favourable antibacterial performances against both Gram-negativeEscherichia coli (E. coli)and Gram-positive (S. aureus) bacteria. Furthermore, animal experiments indicated that the hybrid nanozyme could availably promote wound repair employing satisfied biosafety. Therefore, this present study demonstrates that the fabricated hybrid nanozyme is a prospective alternative for bacteria infected wound healing, which has showed great potential for achieving non-poisonous wound repair healing in future clinical antimicrobial therapy.
New Explicit Solutions of Zoomeron Equation Using Optimal Indexing Approach
Authors: Ahmad Khalil , m Tehree , Naeem Muhammad
Published: August 2023

This paper presents a nonlinear physical model called the (2+1)-dimensional Zomeron equation, which is one of the equations that describes latent evolution. We apply the Power Index Method (PIM) to find analytical solutions of equations using function transformations with optimal indexing of one variable. After selecting index of the variable, then we adopt function transform of another variable that make sure all coefficient terms to change in new variable. PIM is a straightforward mathematical technique in which the indices of the independent variables are adjusted to our selected similarity transformations to effectively reduce the partial differential equation to an Ordinary Differential Equation (ODE). Several exact solutions of the nonlinear Zoumron equation have been built and are presented graphically for some values of the constant parameters. The proposed method has been effectively used to find new exact solutions of nonlinear PDE. Using these transforms, we can easily produce infinitesimal generators of the PDE.
The role of intraoperative pulmonary artery pressure monitoring in the postoperative management of infants with ventricular septal defect and pulmonary hypertension
Authors: Araki Haruna , Shikata Fumiaki , Torii Shinzo , Kitamura Tadashi , Mishima Toshiaki , Fukuzumi Masaomi , Fujioka Shunichiro , Horikoshi Rihito , Tamura Yoshimi , Ishiwaki Daiki , Miyaji Kagami
Published: August 2023

Background
The fast-track approach in pediatric cardiac surgery shortens hospital stays and reduces medical costs. This study aims to evaluate the feasibility of the fast-track approach and the role of intraoperative pulmonary artery pressure (PAP) monitoring in managing patients with preoperative pulmonary hypertension (PH) who underwent ventricular septal defect (VSD) closure.
Methods
This retrospective study included 94 infants with VSD and preoperative PH. Intraoperative systolic PAP monitoring was performed to evaluate the suitability of the fast-track approach (< 35 mmHg). Postoperative adverse events included in-hospital death, PH crisis and prolonged mechanical ventilation time, and nitric oxide (NO) administration.
Results
The fast-track approach was carried out in 35 patients (37%). One in-hospital death (1%) occurred in a non-fast-track patient due to postoperative PH crisis. Two patients (5.7%) required re-intubation after the fast-track approach due to upper airway issues. The frequency of NO inhalation and administration of pulmonary hypertensive medicines was significantly lower in the fast-track group than in the non-fast-track group (P < 0.001). Multivariate analysis revealed that body weight of < 4 kg at surgery was (P = 0.006), surgery by trainees (P = 0.002), and greater intraoperative systolic PAP (P < 0.001) were significant risk factors for postoperative adverse events.
Conclusions
Our findings showed that the fast-track approach after VSD closure in infants with preoperative PH was feasible as indicated by the low frequency of re-intubation and postoperative adverse events. Intraoperative systolic PAP measurement was useful for selecting patient to be included in the fast-track approach.
Prevalence and correlates of sleep disturbance among adolescents in the eastern seaboard of China: a cross-sectional study
Authors: Yang Haidong , Luan Lingshu , Xu Jiuli , Xu Xingran , Tang Xiaowei , Zhang Xiaobin
Published: August 2023

Background
Sleep disturbances are serious public health issues that warrant increased attention, especially in adolescents. The aim of this study was to investigate the prevalence and factors associated with sleep disorders among urban adolescents in China.
Methods
This study utilized an online survey to assess the demographic characteristics and mental health status of secondary school students in Lianyungang City. The Patient Health Questionnaire-9 (PHQ-9) was used to evaluate suicidal ideation and sleep disturbances in adolescents. The seven-item Generalized Anxiety Disorder (GAD-7) assessed anxiety symptoms, and the Perceived Social Support Scale (PSSS) was used to measure perceived social support.
Results
Among 3443 adolescents, the prevalence of sleep disorders were 10.8%, with significantly higher proportions of sleep disorders (13.7% VS 8.3%, χ2 = 26.559, P < 0.001) among female adolescents when compared to males. Binary regression analysis revealed that suicidal ideation (OR = 2.558, 95% CI: 1.897–3.450, P < 0.001) and anxiety symptoms (OR = 9.899, 95% CI: 7.317–13.393, P < 0.001) were risk factors for sleep disturbances, and significant other support (OR = 0.940, 95% CI: 0.894–0.989, P = 0.016) and good annual household income (OR = 0.661, 95% CI: 0.396–0.943, P = 0.026) were protective factors. Furthermore, multinomial logistic regression analysis showed that sex, suicidal ideation, anxiety symptoms, and parental relationship were associated with an elevated risk of experiencing more frequent sleep disturbances (all P < 0.05).
Conclusions
We have found that 10.8% of adolescents experience sleep disorders, and it is evident that various factors can influence healthy sleeping. These results underscore the significance of addressing these factors to enhance sleep health among this population.
A promising composite room temperature solid electrolyte via Incorporating LLZTO into Cross-linked ETPTA/PEO/SN matrix for all solid state lithium batteries
Authors: Li Bangxing , Yi Xianlin , Wu Fei , Kang Xing , Hu Xiaolin
Published: August 2023

Composite solid electrolyte (CSE), especially the composite room temperature solid electrolyte (CRTSE), is emerging as the promising electrolyte for all-solid-state lithium batteries (ASSLB) due to their ability to combine the desirable properties of ceramic and polymer-based electrolytes, and the room temperature operation condition. In this paper, the CRTSE with polyethylene oxide (PEO), Bis (fluorosulfonyl)imide (LiTFSI), Succinonitrile (SN), LLZTO inorganic fillers and cross-linked ethoxylated trimethylolpropane triacrylate (ETPTA) was proposed. With the help of the suppression dendrite growth of lithium via cross-linked microscopic pore structure, enhancement of the ionic conductivity via LLZTO fillers, wide electrochemical window via SN, the obtained CRTSE shown high ionic conductivity (2.12 × 10-4 S cm-1), high Li+ transfer number (tLi+=0.55), stable electrochemical window (5.0 V vs Li/Li+) at room temperature. The Li symmetrical cell can cycle over 500 hours stably with current density of 0.1 mA cm-2 and 0.5 mA cm-2 at room temperature. The full solid state LiFePO4 cell can successfully work over 200 cycles with capacity retention ratio of about 70% at room temperature.
On some conjectural series containing harmonic numbers of 3-order
Authors: Wei Chuanan , Xu Ce
Published: August 2023

Harmonic numbers are important in a lot of branches of number theory. By means of the derivative operator, the integral operator, and several summation and transformation formulas for hypergeometric series, we prove four series containing harmonic numbers of 3-order. Three of them are conjectures which were recently proposed by Z.-W. Sun.
Synthesis, Structural confirmation, Hirshfeld surface analysis, DFT Mechanistic and ADMET Properties of (E)-N-(4-bromobenzylidene)-3-methoxybenzohydrazide Monohydrate
Authors: Ananthi Kumar , Anandalakshmi Haridhass , Nepolraj Amaladoss , Akshaya Saravanan
Published: August 2023

Synthesis and structural elucidation of a novel, organic, hydrazone Schiff base compound and its structure was characterized by FT-IR, 1H, 13C NMR and mass spectroscopic analysis. The single crystals of (4-BRMBH) were grown from the DMSO. The compound (C15H13BrN2O3) crystallized at (E)-N'-(4-bromobenzylidene)-3-methoxybenzohydrazide monohydrate orthorhombic system with P212121 space group through single-crystal X-ray diffraction analysis. The compound is subjected to antimicrobial (antibacterial, antifungal) activities. Theoretical studies were performed using DFT by Gaussian 09 to develop the optimized geometry. Intermolecular interactions in the crystal structures were obtained using the Hirshfeld surface analysis. The majority contribution to the Hirshfeld surface is H×××H (39.5%) contacts. The molecular docking study were carried out by in silico method to analyse their anti-tuberculosis aspect against InhA, the enoyl acyl carrier protein reductase from Mycobacterium tuberculosis.
A comparison of the electrochemical oxidative dissolution of pyrite and chalcopyrite in diluted nitric acid solution
Authors: Teimouri Samaneh , Potgieter Johannes Herman , Billing Caren
Published: August 2023

Understanding the oxidation of sulfidic minerals, especially those of pyrite and chalcopyrite, under acidic conditions has important outcomes, such as exposing any encapsulated gold not recovered by traditional cyanidation processes and providing insight into acid mine drainage. This investigation studied the electrochemical oxidation of pyrite and chalcopyrite in a nitric acid solution (0.5 M) using electrochemical techniques. Cyclic voltammetry (CV) was performed using electrodes of each mineral to detect the possible redox reactions and hence suggest products formed from each mineral. Electrochemical impedance spectroscopy (EIS) was also run on each mineral at specific potentials corresponding to regions for anodic reactions detected to gain further information about the reaction mechanism and possible products. The partial oxidation of pyrite at low anodic potentials (0.4 to 0.6 V) produces Fe1-xS2 and Fe(OH)3, with a sulfur-rich layer forming S0 which accumulates on the electrode’s surface, leading to a diffusion controlled dissolution process. As the potential increases above 0.7 V, there is sufficient driving force to fully oxidise pyrite and the species already formed on the electrode’s surface to soluble species by producing SO42–. This eradicates the diffusion barrier and cause extensive oxidation of pyrite at high potentials (0.9 V). A similar process occurred for chalcopyrite with preferential oxidation of iron at low potentials (0.3 to 0.5 V), forming mainly iron and copper deficient sulfides (like Cu1-xFe1-yS2-z, CuS2, CuS) and S0 which partially covers the chalcopyrite electrode’s surface, causing a diffusion barrier. Increasing the potential to beyond 0.7 V leads to these previously formed layers converting to soluble species. EIS provides evidence supporting the reactions and the formed products at the investigated potentials.
Two steps electrochemical reduction of graphene oxide modified Pb-carbon negative current collector: Synthesis and characterization
Authors: Jhabli Oussama , Jersifi[ Adnane El , Mouchtari El Mountassir El , Boutamart Mustapha , Rafqah Salah , Laamari My Rachid , Redouany Yassine , Nouneh Khalid , Galai Mouhsine , Hssissou Rachid , Briche Samir
Published: August 2023

The authors have requested that this preprint be removed from Research Square.
Transcriptomic Analysis Reveals Potential Genes and Essential Biological Processes Controlling the Robust Immune Response to Trivalent Inactivated Influenza Vaccine in Healthy Adults
Authors: Tawfik Ahmed
Published: August 2023

The seasonal influenza vaccine remains one of the vital recommended infection control measures for healthy individuals and the elderly with chronic illnesses. Nonetheless, a universal vaccine, which can be administered once and offer long-term protection against influenza, still has a few steps to go before it becomes available to the general public. We investigated the immunogenicity of a single dose of influenza vaccine in 123 seronegative participants and classified them into four distinct groups, determined by the promptness of their vaccine response, the longevity of their humoral immunity, and the likelihood of exhibiting cross-reactivity. Subsequently, we used transcriptional profiling and differential gene expression analysis to identify potential genes directly associated with the robust response to the vaccine. Our findings point out a list of expressed proteins that are related to B cell proliferation, unfolded protein response and cellular hemostasis, as well as a linkage of these expressions to the survival of long-lived plasma cells.
Integrative analysis of PAIP2B identify a novel biomarker for pancreatic ductal adenocarcinoma
Authors: Xiang Yaoxian
Published: August 2023

The aim of the study was to evaluate the potential diagnostic and prognostic value of PAIP2B in pancreatic cancer. We used the gene expression data and clinical information of PAAD from The Cancer Genome Atlas (TCGA) database and Gene Expression Omnibus (GEO) database to analyze the expression of PAIP2B in pancreatic cancer samples, and validated the expression of PAIP2B in tumor tissue. Using bioinformatics technology to explore the prognostic value of PAIP2B and its possible biological function. A significantly lower level of PAIP2B was observed in pancreatic cancer patients than in controls, and validated by Immunohistochemistry. PAIP2B declined the proliferation and invasion of cancer cells and was significantly high expression in early stage. Patients with lower levels of PAIP2B had a significantly shorter median survival time than those with higher levels. DNA demethylation played an important role in PAIP2B expression. In addition, PAIP2B expression was significantly associated with the tumor-infiltrating immune cells, especially T-cells CD8, T-cells CD4 memory resting, Macrophages M0 and Dendritic cells resting. Our study also evidenced that PAIP2B regulated miRNA function leading to disease progression in pancreatic cancer patients. Our study explored the potential value of PAIP2B as a biological link between prognosis and pancreatic cancer, and provided reference for the follow-up study on the role of PAIP2B in pancreatic cancer.
Metagenomic profiling for gut of indigenous poultry reared under free range system of management reveal prevalence of zoonotic pathogens in chicken, while predominating beneficial microbes in duck
Authors: Pal Aruna , Debnath Manti , Chatterjee Paresh
Published: August 2023

Zoonosis is an important phenomenon of disease transmission through livestock and poultry. In the current study, we explored gut metagenomics and identified a heavy percentage of pathogenic microbial loads in small intestine (duodenum) of chicken in comparison to duodenum of duck. Another important observation was that the percentage of pathogenic microbe decreases in large intestine (caecum), thereby reducing the chance of disease transmission through faeces. This may be the reason how indigenous duck and chicken were more hardy and resistant to common avian pathogens, that they have the ability to manage the reduction of the pathogenic microbes ingested through free range grazing with the help of beneficial microbes in caecum. Significant microbial load have been observed for Chlamydia abortus and Nocardia nova, with the every possibilities of transmission from chicken duodenum, so, handling of chicken need to be carried out with utmost care. We observed a remarkable finding that caecum of the gut reveal very less percentage of these pathogenic microbes, rather caecum is dominated by a beneficial microbe. 10 percent of the duck caecum is inhabited by Bacteroides spp (7 percent of Bacteroides sp OF04-15BH and 3 percent of Bacteriodes plebius), while it is almost negligible in chicken. This is the first report of this kind. This may be employed for the isolation and utilization as future probiotics from a ready source. Scavenging by indigenous poultry may serve as a useful tool for reducing pathogens prevailing in the environment.
Association between organizational support and turnover intention in nurses: a systematic review and meta-analysis
Authors: Galanis Petros , Moisoglou Ioannis , Katsiroumpa Aglaia , Vraka Irene , Siskou Olga , Konstantakopoulou Olympia , Kaitelidou Daphne
Published: August 2023

Aims
To synthesize and evaluate the association between organizational support and turnover intention in nurses.
Design:
We applied the Cochrane criteria and the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines for our review and meta-analysis. The review protocol was registered with PROSPERO (CRD42023447109).
Data sources:
We searched PubMed, Medline, Scopus, Cinahl, Web of Science, and Cochrane from inception to July 21, 2023.
Review Methods:
Heterogeneity between results was high. Thus, we applied a random effect model to estimate pooled correlation coefficient between organizational support and turnover intention.
Results
A total of eight studies with 5,754 nurses were included. We found a moderate negative correlation between organizational support and turnover intention since the pooled correlation coefficient was − 0.32. A leave-one-out sensitivity analysis showed that our results were stable when each study was excluded. Egger’s test and funnel plot suggested the absence of publication bias in the eight studies. Subgroup analysis showed that the negative correlation between organizational support and turnover intention was stronger in studies in China and Australia than those in Europe.
Conclusion
Organizational support has a moderate negative correlation with turnover intention in nurses. However, our study had several limitations and we cannot generalize our results. Thus, further studies should be conducted to assess the independent effect of organizational support on turnover intention in a more valid way.
Impact:
Since organizational support is related with turnover intention, healthcare systems, organizations, and policy makers should develop and implement appropriate interventions to support nurses and improve working conditions. Nursing managers should draw attention to organizational support by developing effective clinical practice guidelines for nurses, so as to reduce turnover intention.
Pengembangan e-LKM Terintegrasi Literasi Numerasi untuk Meningkatkan Berpikir Kritis pada Materi Analisis Vektor
Authors: Peni Nur Robiah Nofikusumawati , Sumargiyani Sumargiyani , Prasetyo Puguh Wahyu
Published: August 2023

Students' low reading interest greatly affects learning outcomes in Vector Analysis class. This is due to the rare interaction between students and learning resources in class. To increase student activity in reading and understanding the concept of vector analysis material, an e-LKM product is needed. This study aims to develop Student Worksheets (LKM) in electronic form that is integrated with numeracy literacy which can be used for learning vector analysis courses by knowing the validity and practicality of procedures so that the use of these e-LKM can improve students' critical thinking. This development research uses the ADDIE model (Analysis, Design, Development, Implementation, and Evaluation). Furthermore, the evaluation stage is carried out at each stage to improve the e-LKM that is made. The subjects were 21 students in semester VI of class C Mathematics Education FKIP Universitas Ahmad Dahlan. The research data was obtained by collecting questionnaires from material experts, media, and students' responses to the practicality of the media being developed. From the results of the questionnaires distributed, the average questionnaire from the two material experts and media experts showed excellent criteria with a mean score of 4.611 and 4.47 respectively. The results of student responses to product use show excellent criteria with a mean score of 4.27. Based on these results, the e-LKM that is used is proven to be valid and practical.
Small vet, big cow: Tips and tricks for the vertically challenged
Authors: Homerosky Elizabeth R.
Published: August 2023

Regardless of your stature, it is critical you understand your strengths and weaknesses. Gaining experience and confidence in clinical skills, particularly obstetrical procedures, takes considerable time. Dystocias are a team sport and as such, you should never hesitate to reach out to colleagues for guidance or employ the client’s assistance. In many instances, casting a cow down will improve your ability to control the situation and safely assist the cow. Maintaining an open mind and sense of humor will serve you well in a multitude of situations.
Practical fetotomies
Authors: Betts Michael
Published: August 2023

Dystocias can take on many forms and knowledge of when to perform a fetotomy vs a C-section can be a major headache sav­er. While there are places around the country where C-sections have been abandoned exclusively for performing a fetotomy and vice versa, my practice area has always been open to both procedures. This passage from the 1972 book Fetotomy in Large Animals by C J Bierschwal and CHW deBois sums it nicely:

Fetotomy should not be considered a substitute for Cesarean section. Both have a place in veterinary practice, the choice of method in in­dividual cases being governed by the circumstances. After the finding of a dead fetus in the case of dystocia, the uppermost question should be “Which is the better solution with regard to the life of the dam?” The answer may not be the easier procedure or the one involving the least amount of effort.

The advent of sexed semen and beef on dairy technologies have seemed to greatly reduce the volume of dystocias due to large calves. That generally leaves malpositioned calves, emphyse­matous calves and the occasional fetal monster. Discussion of all presentations of dystocia are beyond the scope of this paper. The techniques presented here are a foundation that the veteri­nary obstetrician should be familiar with in order to apply to fetal presentations not discussed here.
Practical palpation tips and tricks for cow-calf
Authors: Long Christine
Published: August 2023

Palpating cows takes time and practice; however, consistent use of these tips and tricks will leave you guessing less and feel­ing more confident behind the cow. This session is designed to bring back a practical and systematic approach to palpating cows no matter their stage of gestation.
Cultural awareness for veterinarians working with LatinX livestock caretakers
Authors: Noami Román-Muñiz Ivette
Published: August 2023

Work done by Colorado State University researchers has high­lighted the human-animal bond that exists on dairy and other livestock operations, and the perceptions of animal caretakers regarding animal health and euthanasia decisions. There is a clear need for culturally responsive training to better prepare animal caretakers to make end-of-life decisions in a timely manner while reducing the emotional burden associated with euthanasia decision making. While veterinarians are well po­sitioned to provide leadership in health management and end-of-life decision-making processes, they are seldom involved in the creation and facilitation of training programs for livestock caretakers. Cultural differences that may limit effective com­munication and training can be overcome by engaging live­stock caretakers with approaches proven effective in both re­search and practice settings.
What you need to know before becoming an owner
Authors: Seckerson Portia
Published: August 2023

Are you bored in the everyday grind of practice? Are you frus­trated with your current boss and how things are managed? Is one of your goals to be a business owner? Are you ready for another challenge in life? If you find yourself answering yes to these questions, you are ready to start taking the leap. Being a large animal veterinarian is a truly rewarding, exciting and challenging job. With any job there comes some frustrations, but by being a business owner you can have a direct impact on what frustrates you. Yes, you will have more and different responsibilities as an owner, but you can make your work-life balance whatever you want it to be. It is never too early to start brainstorming about business ownership.
La disuguaglianza socioeconomica in America Latina e Colombia. Panoramica sulle politiche pubbliche per la redistribuzione della ricchezza
Authors: Riccardi Davide , Agudelo Taborda Jairo , Bossio Blanco Veronica del Carmen
Published: August 2023

In America Latina, la lotta alla disuguaglianza socioeconomica è un tema ricorrente del dibattito politico regionale e globale. Difatti, nonostante i progressi registrati durante l’epoca del boom dei prezzi delle materie prime del periodo 2008-2014, i vari governi non sono riusciti a trasformare la realtà in senso effettivamente equitativo. Attraverso una revisione statistico-documentale, questo articolo ha come obbiettivo quello di analizzare il sistema fiscale di alcuni dei principali Paesi latino-americani, con particolare attenzione verso il caso colombiano. Ne emerge che, con eccezione di Argentina, Brasile e Cuba, la realtà latino-americana è ancora molto distante dai valori di gettito fiscale e spesa sociale della media OCSE. Tale differenziale è causato in particolare da un approccio sostanzialmente regressivo del prelievo fiscale, accompagnato da alti livelli di elusione ed evasione. Ne deriva così che i servizi di welfare (pensioni, salute ed istruzione) non ricevono le risorse necessarie per il loro efficace, efficiente ed universale funzionamento. Ciò scredita così la loro credibilità, specialmente agli occhi delle classi medie e maggiormente agiate che spesso acquistano tali servizi dal settore privato. In virtù di tale dinamica, il welfare latino-americano si trasforma così in una sorta di elemosina che i ceti più agiati versano nei confronti dei meno abbienti. Quest’ottica ideologica è infatti uno degli ostacoli maggiori verso una trasformazione in senso progressivo del sistema fiscale latino-americano che si caratterizza, altresì, per una bassa tassazione sul reddito e sul patrimonio delle persone fisiche se comparata con gli altri Paesi di maggiore industrializzazione.
Keywords: Welfare state; politica fiscale; inclusione sociale; America Latina; Carlo Tassara.
Cohesión Social euro-latinoamericana. In memoriam del profesor Carlo Tassara
Authors: Agudelo Taborda Jairo
Published: August 2023

Este número de la Revista Internacional de Cooperación y Desarrollo está dedicado a una gran alma de la cooperación italiana en Colombia: Carlo Tassara. Junto a Carlo es justo recordar también a su y nuestro amigo y colega Paolo Giorgi, co-fundador y primer director de la Escuela Latinoamericana de Cooperación y Desarrollo (Elacid) en cuyo marco nació esta revista. Paolo nos acompañó por tres años –del 2003 al 2006– junto a su tierna y noble esposa Manuelita Focaia en Cartagena. Nos unimos a ella en memoria de Paolo.

Del mismo modo, Carlo nos acompañó desde el 2003 hasta el 2021 como docente del posgrado de Cooperación internacional al desarrollo, en el nacimiento y la consolidación de esta revista. Infatigable colaborador junto a su esposa Yolanda Zuluaga. Paolo y Carlo tuvieron el doble don de la práctica de la cooperación internacional con los proyectos en los territorios a través de sus respectivas ONG (Coopi y Cisp) y en la reflexión académica desde la Universidad San Buenaventura, la Universidad La Sapienza, la Universidad de Pavía y la Universidad del Norte.

Por su más reciente fallecimiento y por su acompañamiento en los trabajos de la revista, este número recoge artículos que temáticamente interesaron a Carlo Tassara. En modo especial, el apoyo de la cooperación europea a la cohesión social y el desarrollo sostenible en Latinoamérica en general y en Colombia particularmente.
Teaching knowledge development during the FLTA fellowship.pdf
Authors: Mpofu Nhlanhla
Published: August 2023

Transcripts of FTLAs discussion on their teaching knowledge dvelopment during their fellowship at USA universities.  
Antihyperglycemic activity of colostrum peptides
Authors: Tikhonov Sergei , Tikhonova Natalia , Gette Irina , Sokolova Ksenia , Danilova Irina
Published: August 2023

Peptides of plant and animal origin have good anti-diabetic prospects. The research objective was to use bovine colostrum peptides to reduce hyperglycemia in diabetic rats.

Bovine colostrum peptides were obtained by trypsin hydrolysis of colostrum proteins with preliminary extraction of triglycerides. The study involved four groups of Wistar rats with seven animals per group. Group 1 served as control; group 2 received 300 mg/kg of trypsin hydrolysate of bovine colostrum as part of their daily diet for 30 days. Groups 3 and 4 had diabetes mellitus caused by intraperitoneal injections of 110 mg/kg of nicotinamide and 65 mg/kg of streptozotocin. Group 4 also received 300 mg/kg trypsin hydrolysate of bovine colostrum intragastrically five times a week for 30 days.

Three peptides were isolated from the trypsin hydrolysate of bovine colostrum and tested for the sequence of amino acids and molecular weight. Their identification involved the Protein NCBI database, followed by 2D and 3D modeling, which revealed their chemical profile, pharmacological properties, and antioxidant activity. The diabetic rats treated with colostrum peptides had lower glucose, glycated hemoglobin, malondialdehyde, and catalase activity but a higher content of glutathione in the blood. Their leukocytes and erythrocytes also demonstrated less deviation from the standard. The antioxidant effect of colostrum protein hydrolysate depended on a peptide with the amino acid sequence of SQKKKNCPNGTRIRVPGPGP and a mass of 8.4 kDa.

Colostrum peptides reduced hyperglycemia and oxidative stress in diabetic rats. The research revealed good prospects for isolating individual colostrum peptides to be tested for antidiabetic properties.
A thermophilic L-lactic acid producer of high optical purity: isolation and identification
Authors: Romanova Maria , Dolbunova Anastasiia , Epishkina Yulia , Evdokimova Svetlana , Kozlovskiy Mikhail , Kuznetsov Alexander , Khromova Natalya , Beloded Andrey
Published: August 2023

Biodegradable polymers, specifically polylactide, are an important part of food packaging and medical devices. Microbiological synthesis uses cheap renewable raw materials and industrial waste to produce a high yield of lactic acid, the monomer of polylactide. This method needs new effective lactic acid producing strains, e.g., thermophilic bacteria.

The research involved thermophilic bacterial strains isolated from soil and compost samples. Their ability to produce organic acids and extracellular enzymes was tested using the method of high-performance liquid chromatography (HPLC) and microbiological tests respectively. The real-time polymerase chain reaction method (PCR) detected L-lactate dehydrogenase structural genes of L-lactate dehydrogenase of Bacillaceae. Strain T7.1 was fermented using glucose and yeast extract as carbon and nitrogen sources, respectively. The optical purity of lactic acid was evaluated using quantitative gas chromatography on a chiral column to separate lactate isomers. The molecular genetic analysis of the 16S rRNA gene sequence was applied to identify strain T7.1.

The chromatographic analysis proved that 10 out of 13 isolated thermophilic strains were effective lactic acid producers. They demonstrated proteolytic, amylolytic, or cellulase activities. During the fermentation, strain T7.1 produced 81 g/L of lactic acid with a peak productivity at 1.58 g/(L·h). The optical purity of the product exceeded 99.9% L-lactate. The genetic analysis identified strain T7.1 as Weizmannia coagulans (Bacillus coagulans).

The research revealed a promising thermophilic producer of optically pure L-lactic acid. Further research is needed to optimize the cultivation conditions, design an effective and cheap nutrient medium, and develop engineering and technological solutions to increase the yield.
Hematological parameters of free-ranging moose Alces alces (Linnaeus 1758) (Ruminantia, Cervidae)
Authors: Perevozchikova Maria , Domsky Igor , Sergeyev Alexey
Published: August 2023

Comparative studies that feature the physiology of wild and domestic animals replenish the fundamental knowledge in the field of biology and adaptive potential, thus increasing the efficiency of domestication. Semi-free conditions and artificial environment create prerequisites for epidemics and stress. However, early detection can prevent critical situations. This research provides new data on moose biology and physiology by establishing age and sex hematological parameters.

The study featured moose blood samples (n = 55) obtained in the Kirov Region in the northeast of European Russia. Hematological tests relied on a veterinary version of a MicroCC-20 Plus automatic analyzer (High Technology).

This research was the first of its kind to introduce a comparative hematological analysis of local European moose according to age and sex. Adults and calves demonstrated significant differences (p < 0.05) in red blood cells, hemoglobin, hematocrit, mean corpuscular volume, mean concentration hemoglobin, mean corpuscular hemoglobin concentration, platelet distribution width, red blood cell distribution width, platelet crit, platelets, leukocytes, and eosinophils. Females and males also had significant differences (p < 0.05) in red blood cells, hemoglobin, mean corpuscular volume, red blood cell distribution width, platelet distribution width, platelets, and eosinophil content. The single- and multivariate analysis made it possible to establish the effect of physiological factors on the blood parameters in moose.

The hematological values were in line with the most indicators reported in other publications on wild artiodactyls. The existing differences in blood parameters depended on the species, habitat, food supply, age, and sex.
Dialética e Representação da Informação
Authors: Gaudêncio Sale Mário , Albuquerque Maria Elizabeth Baltar Carneiro de , Côrtes Gisele Rocha
Published: August 2023

Apresenta investigação sobre a relação entre a Representação da Informação e a Dialética, demonstrando que enquanto campos de estudos podem contribuir para um repensar da forma como o conhecimento pode se estabelecer. Traz como questão-chave: Por qual motivo devemos fazer uso dos princípios que regem a Dialética para representar cibercordéis? Para responder a esse problema de pesquisa, tem-se como objetivo geral: Apresentar a Dialética como uma proposta teórico-metodológica capaz de auxiliar no processo de Representação da Informação de cibercordéis. Metodologicamente, a investigação é qualitativa, trazendo como a abordagem o próprio Campo da Dialética e corpus, os Cordéis Digitais (cibercordéis) presentes em grupos de facebook com buscas orientadas pela hashtag cordel (#cordel). Nos resultados identificou-se a presença de 8 (oito) Marcadores Sociais, a saber: Classe Social, Étnico-racial, Gênero, Geração, Nacionalidade, Regionalidade, Religião e Sexualidade. Uma vez categorizados, com a análise dos dados, foi possível melhorar o processo de Representação da Informação através do uso do princípio da contradição, por exemplo, e assim, tornar a prática informacional mais robusta e eficaz. Nas conclusões, foi possível chegar a um posicionamento basilar para podermos compreender a ideia do que é Representação Dialética da Informação, especialmente, se tomado como ponto de apoio e partida, princípios como os da contradição e o da totalidade.
Relações e aproximações entre competência em informação e inclusão digital
Authors: Santos Márcio Adriano Costa dos , Terra Guillermina de Melo , LLarena Rosilene Agapito da Silva
Published: August 2023

Analisa as relações teóricas e empíricas entre os termos “Competência em Informação” e “Inclusão Digital”; “Competência Informacional” e “Inclusão Digital”; “Competência Crítica em Informação” e “Inclusão Digital”. De natureza básica, bibliográfica, documental, descritiva e análise de conteúdo. Para tanto, utiliza-se o método quali-quantitativo. Como resultado, afirma-se que, o principal desafio da CoInfo na conjuntura atual estar centrado nos processos de exclusão digital sistêmica em escala global, à medida que não há Sociedade da Informação sem consciência cidadã, bem como justiça epistêmica na era digital. Portanto, afirmar-se que, a aquisição de CoInfo vai de encontro a apropriação oportunista dialética dos políticos, que, usam a inclusão digital como algo feito e acabado simplesmente pela doação e instalação de kits de computadores e acesso à internet no Brasil, nos últimos 23 anos de implantação da sociedade da informação.
Antithrombotic Treatment in Coronary Artery Disease
Authors: Siasos Gerasimos , Tsigkou Vasiliki , Bletsa Evanthia , Stampouloglou Panagiota K. , Oikonomou Evangelos , Kalogeras Konstantinos , Katsarou Ourania , Pesiridis Theodoros , Vavuranakis Manolis , Tousoulis Dimitris
Published: August 2023

Coronary artery disease exhibits growing mortality and morbidity worldwide despite the advances in
pharmacotherapy and coronary intervention. Coronary artery disease is classified in the acute coronary syndromes
and chronic coronary syndromes according to the most recent guidelines of the European Society of
Cardiology. Antithrombotic treatment is the cornerstone of therapy in coronary artery disease due to the
involvement of atherothrombosis in the pathophysiology of the disease. Administration of antiplatelet agents,
anticoagulants and fibrinolytics reduce ischemic risk, which is amplified early post-acute coronary syndromes
or post percutaneous coronary intervention; though, antithrombotic treatment increases the risk for bleeding.
The balance between ischemic and bleeding risk is difficult to achieve and is affected by patient characteristics,
procedural parameters, concomitant medications and pharmacologic characteristics of the antithrombotic
agents. Several pharmacological strategies have been evaluated in patients with coronary artery disease, such as
the effectiveness and safety of antithrombotic agents, optimal dual antiplatelet treatment schemes and duration,
aspirin de-escalation strategies of dual antiplatelet regimens, dual inhibition pathway strategies as well as triple
antithrombotic therapy. Future studies are needed in order to investigate the gaps in our knowledge, including
special populations.
Two-cylinder Synchronous Electro-hydraulic Servo System and its Control
Technology Development
Authors: Li Jianying , Ji Hui , Kong Lingbing , Jiang Liqun
Published: August 2023

Background:

Electro-hydraulic servo control system synchronous control in industrial application is very extensive because the application of electro-hydraulic servo control system is mostly in a poor working environment, there are a variety of complex external factors.

Objective:

Improve the comprehensive performance indicators such as accuracy, speed, and stability of synchronous control of hydraulic cylinders

Methods:

In the process of synchronous movement, the typical hardware structure and control methods and algorithm strategies of the double hydraulic cylinder are analyzed in detail, and the basic principle of common hydraulic double cylinder synchronous control is summarized.

Results:

Through the comprehensive analysis of papers and patent documents related to the synchronous control of hydraulic twin cylinders, these papers and patented technologies study the control algorithm, and apply the new technology to the synchronous control of electro-hydraulic servo hydraulic cylinders to improve its comprehensive performance indicators such as work accuracy, speed and stability.

Conclusion:

Referring to the development trajectory of control algorithms in this regard, combined with new control theory and new technology, many achievements can be applied and researched in hydraulic cylinder synchronous control, and better develop the synchronous control system when double hydraulic cylinders and more hydraulic cylinders work together. By collating and analyzing the relevant research results, the two-cylinder synchronous control technology is comprehensively evaluated and prospected, which provides a valuable reference for the research and application in this field.
Thin Ga-doped ZnO Film with Enhanced Dual Visible Lines Emission
Authors: Alamdari Sanaz , Mansourian Mohammad , Ghamsari Morteza Sasani
Published: August 2023

Introduction:

In this study, a simple and facile route was employed to prepare a highly
transparent and luminescent ultra-thin gallium doped ZnO film (GZO).

Methods:

The thin GZO film has been deposited using the simultaneously ultrasonic vibration and
sol-gel spin-spray coating technique. The structural and optical properties of pure and doped thin films
were investigated by various methods, such as X-ray diffraction (XRD), X-ray photoemission spectroscopy
(XPS), scanning electron microscopy (SEM), UV-Vis, and PL spectroscopy.

Results:

XRD results indicated that both pure and doped ZnO films had a hexagonal wurtzite structure
with (101) preferred orientation. XPS and EDX studies confirmed the incorporation and presence of
Ga ions into the ZnO lattice structure. The doped sample showed nearly 90% of transparency, and a
strong blue-green emission in the visible region.

Conclusion:

The obtained results proved that the prepared thin film could be a novel candidate for optoelectronic
applications.
Decision Tree
Authors: Wang Zhiyuan , Ameenuddin Irfan Sayed , Teoh Christopher , Hriday Bhoyar Priyanka
Published: August 2023

In this chapter, we explore the concept of decision trees, prioritizing accessibility by
minimizing abstract mathematical theories. We examine a concrete numerical example using a
small dataset to predict the suitability of playing tennis based on weather conditions, guiding
readers through the process step-by-step. Moreover, we provide sample codes and compare
them with the decision tree classification model found in the scikit-learn library. Upon
completing this chapter, readers will have gained a comprehensive understanding of the inner
workings of decision tree machine learning, the relationship between the underlying principles,
and the implementation and performance of the algorithm, preparing them to apply their
knowledge to practical scenarios.