bluuebunny/crossref_metadata_2025 huggingface dataset:
PictoAndes: A Customizable Communication Board for Inclusive Education and Multicultural Accessibility
Authors: Carrión-Toro Mayra , Morales-Martínez David , Santórum Marco , Vizuete Alexis , Maldonado-Garcés Verónica , Acosta-Vargas Patricia
Published: January 2025

Children with speech and language difficulties often face significant challenges in expressing their needs, emotions, and thoughts, which can lead to frustration, social isolation, and hindered participation in educational and social activities. Addressing this issue, we present a customizable communication board designed to facilitate effective and autonomous communication for these children. Unlike traditional solutions, this application offers a culturally adaptive and user-centered approach, enabling the inclusion of personalized pictograms, such as representations of familiar objects, to create a more relatable and engaging gamified experience. The platform “PictoAndes” leverages modern technology and gamification principles to transform therapy into an interactive and motivating process. By integrating pictograms that resonate with users’ unique contexts, the board enhances communication, strengthens emotional connections, and fosters a sense of belonging. Built on agile methodologies, the application provides a dynamic solution that adapts to individual needs and evolving challenges, ensuring accessibility and inclusivity. The evaluation of the platform, guided by WCAG 2.1 accessibility standards, demonstrates its effectiveness in reducing communication barriers and promoting active participation. Aligned with the United Nations Sustainable Development Goals (SDGs) 4 and 10, this project contributes to inclusive education and reduced inequalities by offering a practical and transformative tool. By empowering children to express themselves in meaningful ways, the customizable communication board represents a significant step toward enhancing the quality of life and fostering social inclusion for individuals with speech and language difficulties.
Integrating Transformer Architecture and Householder Transformations for Enhanced Temporal Knowledge Graph Embedding in DuaTHP
Authors: Chen Yutong , Li Xia , Liu Yang , Hu Tiangui
Published: January 2025

The rapid advancement of knowledge graph (KG) technology has led to the emergence of temporal knowledge graphs (TKGs), which represent dynamic relationships over time. Temporal knowledge graph embedding (TKGE) techniques are commonly employed for link prediction and knowledge graph completion, among other tasks. However, existing TKGE models mainly rely on basic arithmetic operations, such as addition, subtraction, and multiplication, which limits their capacity to capture complex, non-linear relationships between entities. Moreover, many neural network-based TKGE models focus on static entities and relationships, overlooking the temporal dynamics of entity neighborhoods and their potential for encoding relational patterns, which can result in significant semantic loss. To address these limitations, we propose DuaTHP, a novel model that integrates Transformer blocks with Householder projections in the dual quaternion space. DuaTHP utilizes Householder projections to map head-to-tail entity relations, effectively capturing key relational patterns. The model incorporates two Transformer blocks: the entity Transformer, which models entity–relationship interactions, and the context Transformer, which aggregates relational and temporal information. Additionally, we introduce a time-restricted neighbor selector, which focuses on neighbors interacting within a specific time frame to enhance domain-specific analysis. Experimental results demonstrate that DuaTHP significantly outperforms existing methods in link prediction and knowledge graph completion, effectively addressing both semantic loss and time-related issues in TKGs.
Toxicological Assessment of Ketamine in Juvenile Zebrafish (Danio rerio)
Authors: Tang Yin , Yang Kang , Xu Jintao , Qiu Yangkai , Meng Liang , Zhao Sen
Published: January 2025

This study investigates the toxic effects of ketamine on juvenile zebrafish, driven by increasing concerns over ketamine’s prevalence and its potential neurotoxic effects that may disrupt behavior and metabolism. Employing a high-throughput behavior tracking system, the research analyzed the locomotor activity of 6-day post-fertilization (6 dpf) zebrafish exposed to various concentrations of ketamine. The integration of behavioral analysis with metabolic profiling was a notable innovation, as it establishes a comprehensive understanding of ketamine’s effects on both acute behavioral inhibition and metabolic responses. The findings reveal that ketamine exposure significantly inhibits locomotor activity in juvenile zebrafish, with these effects becoming more pronounced at higher concentrations. Additionally, the detection of normethketamine, the primary metabolite of ketamine, using UPLC-LTQ/Orbitrap HRMS, confirms the zebrafish’s ability to metabolize the drug. This underscores the utility of zebrafish as a model organism for studying the impact of ketamine on behavior and metabolism, providing valuable insights that may extend to other vertebrates.
Soil Texture Mediates the Toxicity of ZnO and Fe3O4 Nanoparticles to Microbial Activity
Authors: Shah Ghulam Mustafa , Shabbir Zunaira , Rabbani Faiz , Rashid Muhammad Imtiaz , Bakhat Hafiz Faiq , Naeem Muhammad Asif , Abbas Ghulam , Shah Ghulam Abbas , Shahid Naeem
Published: January 2025

The widespread use of metal oxide nanoparticles (NPs) in industrial and household products has raised concerns about their potential soil contamination and its ecological consequences. The purpose of this study was to examine and compare the effects of iron oxide nanoparticles (FeONPs) and zinc oxide nanoparticles (ZnONPs) on the microbial activity and biochemical properties of differently textured soils. A mesocosm experiment was conducted using three soil types–clay loam (CL), sandy clay loam (SCL), and sandy loam (SL) amended with farmyard manure (FYM), ZnONPs and/or FeONPs. The results revealed significant differences in microbial colony-forming units (CFUs) and carbon dioxide (CO2) emissions in the order of SL > SCL > CL. Compared with those from the unfertilized control, the CO2 emissions from the FYM increased by 112%, 184% and 221% for CL, SCL and SL, respectively. The addition of ZnONPs and FeONPs notably increased the microbial biomass Zn/Fe, which reflected their consumption by the soil microbes. As a result, microbial CFUs were considerably reduced, which led to a 24%, 8% and 12% reduction in cumulative CO2 emissions after the addition of ZnONPs to the CL, SCL and SL soils, respectively. The respective decrements in the case of FeONPs were 19%, 2% and 12%. The temporal dynamics of CO2 emissions revealed that the CO2 emissions from CL with or without FYM/NPs did not differ much during the first few days and later became pronounced with time. Almost all the studied chemical characteristics of the soils were not strongly affected by the ZnONPs/FeONPs, except EC, which decreased with the addition of these nanomaterials to the manure-amended soils. Principal component analysis revealed that the ZnONPs and FeONPs are negatively corelated with microbial CFUs, and CO2 emission, with ZnONPs being more toxic to soil microbes than FeONPs, though their toxicity is strongly influenced by soil texture. Hence, these findings suggest that while both these NPs have the potential to impair microbial activity, their effects are mediated by soil texture.
The Combined Toxic Effects of Polystyrene Microplastics and Arsenate on Lettuce Under Hydroponic Conditions
Authors: Mu Li , Gao Ziwei , Wang Mengyuan , Tang Xin , Hu Xiangang
Published: January 2025

The combined pollution of microplastics (MPs) and arsenic (As) has gradually been recognized as a global environmental problem, which calls for detailed investigation of the synergistic toxic effects of MPs and As on plants and their mechanisms. Therefore, the interaction between polystyrene microplastics (PS-MPs) and arsenate (AsO43−) (in the following text, it is abbreviated as As(V)) and its toxic effects on lettuce were investigated in this study. Firstly, chemisorption was identified as the main mechanism between PS-MPs and As(V) by the analysis of adsorption kinetics, adsorption thermodynamics, and Fourier transform infrared spectroscopy (FTIR). At the same time, the addition of As(V) promoted the penetration of PS-MPs through the continuous endodermal region of the Casparis strip. Furthermore, compared with the CK group, it was found that the co-addition of As(V) exacerbated the lowering effect of PS-MPs on the pH value of the rhizosphere environment and the inhibitory effect on root growth. In the P20V10 group, the pH decreased by 33.0%. Compared to the CK group, P20, P20V1, and P20V10 decreased the chlorophyll content by 68.45% (16 SPAD units), 71.37% (17.73 SPAD units), and 61.74% (15.36 SPAD units) and the root length by 19.31% (4.18 cm), 50.72% (10.98 cm), and 47.90% (10.37 cm) in lettuce. P5V10 and P20V10 increased CAT content by 153.54% (33.22 U·(mgprol)−1) and 182.68% ((38.2 U·(mgprol)−1)), Ca by 31.27% and 37.68%, and Zn by 41.85% and 41.85%, but the presence of As(V) reduced Na by 22.85% (P5V1) and 49.95% (P5V10). The co-exposure significantly affected the physiological and biochemical indicators as well as the nutritional quality of the lettuce. Finally, the metabolomic analysis of the lettuce leaves showed that combined pollution with PS-MPs and As(V) affected the metabolic pathways of the tricarboxylic acid cycle (TCA cycle), sulfur metabolism, and pyruvate metabolism. This study provides data for pollution management measures for co-exposure to PS-MPs and As(V).
The Evaluation of a New ELISA-Based Kit for Total Microcystins as an Early Detection Tool for Microcystin Blooms in Source Waters and Its Application State-Wide to Oregon Source and Finished Drinking Waters
Authors: Adams Katie , Clauson Kale , Adams William A. , Labiosa Rochelle G. , McBride Theresa , Borisenko Aaron , Dyer Stuart W. , Fairchild Ned , Pepich Barry V.
Published: January 2025

Due to cyanobacterial toxin (cyanotoxin) contamination issues in 2018, the city of Salem, Oregon, issued a 33-day do-not-drink advisory for vulnerable people among the 200,000 residents. After the incident, the state of Oregon put in place drinking water rules to require the routine testing of raw water, as well as finished water, in cases where the raw water cyanotoxin concentrations exceeded trigger values. The United States Environmental Protection Agency (EPA) total microcystins drinking water health advisory level (HAL) for small children is 0.3 µg/L. This is equivalent to the minimum reporting level (MRL) for EPA Method 546. Consequently, there was no ability to provide early warnings via toxin testing for total microcystins using the EPA method. In this study, we performed a comparison of the precision and accuracy of the enzyme-linked immunosorbent assay (ELISA) described in the EPA method to a more sensitive assay, the Streptavidin-enhanced Sensitivity (SAES) assay. Based on these precision and accuracy studies and quantitation limit determinations and confirmations, the EPA Office of Ground Water and Drinking Water (OGWDW) has concluded the SAES kit meets the requirements of EPA Method 546. With an MRL that is one-third of the original concentration, the new kit provides a small but critical window for identifying early warnings. Challenges remain with providing early warnings due to the variability in bloom dynamics; however, the new MRL allowed Oregon to lower the trigger level for susceptible systems, thereby providing an additional early warning.
A Network Meta-Analysis on the Impact of Sirolimus vs. Everolimus on Malignancies After Kidney Transplantation
Authors: Wolf Sebastian , Schiele Stefan , Schrempf Matthias , Sommer Florian , Li Mingming , Wirth Ulrich , Werner Jens , Andrassy Joachim
Published: January 2025

Background: mTOR-Is positively influence the occurrence and course of certain tumors after solid organ transplantation. mTOR-inhibitor (mTOR-I) treatment, either alone or in combination with Calcineurininhibitors (CNIs), significantly reduces the incidence of malignancies after organ transplantation. However, there is no information on which mTOR-I, Sirolimus (SIR) or Everolimus (ERL), has a stronger anti-tumoral effect. Methods: The current literature was searched for prospective randomized controlled trials in renal transplantation. There were 1.164 trials screened, of which 20 could be included (7465 patients). We performed a network meta-analysis to analyze the relative risk of different types of mTOR-I compared to CNI treatment on malignancies after transplantation. A minimum follow-up of 24 months was mandatory for inclusion. Results: Four different types of mTOR-I treatment were analyzed in network meta-analyses—SIR mono, ERL mono, SIR with CNI, and ERL with CNI. The average follow-up of all trials was 43.8 months. All four different mTOR-I regimes showed a significant reduced relative risk for malignancies compared to a regular CNI-treatment with the strongest effect under SIR in combination with a CNI (RR 0.23, CI 0.09–0.55, p = 0.001). This effect remained consistent for all tumor entities except non-melanoma skin cancer (RR 0.25, CI 0.07–0.90, p = 0.033). Conclusions: It is well known that an mTOR-I based treatment in transplant patients reduces the risk of tumor manifestation in comparison to CNI treatment. A combination of SIR and CNI seems to be the most potent mTOR-I therapy against malignancies.
Case—Diagnostic Pitfalls with Concurrent Posterior Urethral Valves and Duodenal Atresia
Authors: Ahmad Ihtisham , Khondker Adree , Dos Santos Joana , Romao Rodrigo L. P. , Lorenzo Armando J. , Rickard Mandy
Published: January 2025

Background/Objectives: This case study presents the complex management of a neonate with concurrent posterior urethral valves (PUV) and duodenal atresia (DA), highlighting diagnostic challenges due to overlapping and atypical imaging findings. Methods: A retrospective chart review was performed with a focus on pre- and postnatal imaging and clinical findings throughout the patient’s course of care. Results: A 32-week gestational referral revealed polyhydramnios, a double-bubble sign, and hydronephrosis. DA-associated polyhydramnios masked the expected oligohydramnios and other in utero sonographic signs of PUV, complicating prenatal diagnosis. Postnatally, early urethral stenting for DA repair obscured typical PUV imaging. PUV diagnosis was confirmed by cystoscopy on day 73. Conclusions: We emphasize the importance of multidisciplinary care and appreciating diagnostic uncertainties in neonates with concurrent obstructive uropathy and intestinal obstruction.
Fatal Bluetongue Virus Serotype 3 Infection in Female Dogs: A Case Report from Alentejo, Portugal, 2024
Authors: Barros Sílvia C. , Maroco Diogo , Henriques Ana M. , Costa Maria L. , Alves Alexandra , Ramos Fernanda , Duarte Ana , Fagulha Teresa , Varanda Inês C. , Santos Fábio Abade dos , Ferreira Ana C. , Barahona Maria J. , Carvalho Paulo M. , Orvalho Mariana , Duarte Margarida D.
Published: January 2025

The first official case of bluetongue virus serotype 3 (BTV-3) in Portugal was confirmed in sheep from the district of Évora in September 2024. Notably, mortality was observed in pregnant sheepdogs within the affected sheep flocks. This study presents four cases of pregnant dogs infected with BTV-3 in mid-September 2024, all of which aborted prior to death. BTV-3 was identified by RT-qPCR following initial positive results from pan-BTV RT-qPCR. The virus was subsequently isolated from the blood of one of the dogs in BHK-21 cells, and a partial sequence of the vp2 gene was obtained. This sequence showed 100% similarity to sheep BTV3/3234/PT2024, identified in Portugal in September 2024, as well as to BTV-3/NET2023, first reported in the Netherlands in 2023. These findings suggest that the viruses may be related or share a common origin. Co-infection with common canine viruses and pathogenic bacteria was ruled out, confirming that the fatalities were due to BTV-3 infection, probably by ingestion of sheep placenta after lambing. Our results confirm the potential for the transmission of BTV-3 to non-ruminant species, particularly carnivores, and, therefore, the wider ecological implications of this virus. In addition, the identification of transplacental transmission of BTV-3 in one of the dogs provides new evidence highlighting the complexity of the virus’ transmission mechanisms.
Development and Implementation of a Single Radial Diffusion Technique for Quality Control of Acellular Pertussis Vaccines
Authors: Wu Chongyang , Wang Xi , Zhou Yu , Zhu Xinshuo , Ma Yu , Wei Wenming , Zhang Yuntao
Published: January 2025

Background/Objectives: An assay for protein content is essential but insufficient for quality control of acellular pertussis vaccines, which might consist of up to five components, each needing individual quantification. Generally, purified pertussis antigens such as pertussis toxin (PTx), filamentous haemagglutinin (FHA), and pertactin (PRN) should be detoxified or stabilized chemically before being formulated into vaccine bulk. The use of chemical agents like formaldehyde and glutaraldehyde can alter the immunological reactivity of these antigens, rendering direct assays by methods such as ELISA ineffective. Methods: In this study, a simple method based on single radial diffusion (SRD) using low concentrations of polyclonal antisera against PT toxoid (PTd), FHA, and PRN was developed. By adding a detergent, diffusible subunits are produced regardless of the original physical state of the antigens, making it suitable for quantifying these antigens after chemical treatment. Results: The assay has shown good specificity, accuracy, and precision. Furthermore, it can differentiate between preparations with the same protein concentration but different antigenic contents. A significant positive correlation between the antigen content and the in vivo immunogenicity has also been demonstrated. Conclusions: An assay for quality control and consistency monitoring of combined vaccines containing acellular pertussis antigen components has been established.
Relationship Between Urbanization–Induced Land Use Changes and Flood Risk: Case Study in Chiang Mai, Thailand
Authors: Gu Zhaolong , Phakdimek Sartsin , Nagami Kozo , Komori Daisuke
Published: January 2025

Urban flooding has long been a critical issue, particularly in rapidly urbanizing regions of developing countries, where land use changes—especially the conversion of rice paddies into urban areas—have significantly increased flood risks. This study investigated the impact of urbanization on flood risk taking Chiang Mai, Thailand, as a case study. Based on historical flood data, the study identified and analyzed frequent flood–prone areas in Chiang Mai during the period from 1990 to 2018. By integrating the Rainfall–Runoff–Inundation (RRI) model simulation results and the remote sensing data, the research quantified dynamics in flood risk, exposure, and vulnerability across these frequent flood–prone areas. The findings demonstrated that the conversion of high–exposure paddy fields into urban areas markedly elevated area flood risks, primarily due to the reduction in water retention capacity and the inheritance of the high–exposure characteristics of paddy fields. This study highlighted the importance of integrating sustainable urban planning and land management strategies in rapidly urbanizing regions. Furthermore, this study examined the feasibility of adopting flood characteristics quantification in frequent flood–prone areas as a systematic approach to analyze the dynamic interplay between flood risks and urbanization in developing countries.
Dimensiones de la autorregulación docente: interés intrínseco y orientación a la meta
Authors: Baeza-Sepúlveda Catherine , Sáez-Delgado Fabiola , Mella-Norambuena Javier , López-Angulo Yaranay , Zañartu Carola
Published: January 2025

Este estudio comparó el interés intrínseco y la orientación a la meta de dominio en docentes, según características sociodemográficas durante el retorno a clases presenciales después de la pandemia COVID-19. Se utilizó un diseño descriptivo correlacional transversal. El cuestionario fue respondido por 157 docentes de escuelas secundarias en Chile. Los resultados mostraron una relación significativa y positiva entre interés intrínseco, orientación a la meta de dominio; no existió diferencia significativa en estas variables regulatorias según sexo y tipo de contrato; los docentes con más de 10 años de experiencia presentaron mayores niveles interés intrínseco que docentes con menos años de experiencia, no existió diferencia significativa entre la variable orientación a la meta y años de experiencia. Se requieren más estudios para identificar factores intervinientes que influyan en el interés intrínseco y orientación a la meta del profesorado y consecuentemente permiten mejorar estas variables por medio del modelado en sus estudiantes.
Uso de las TIC y las competencias investigativas en tiempo de pandemia COVID-19
Authors: Fernández Morales Jhanaly Lady Noelia , Sayan Brito Jacqueline Susana
Published: January 2025

Las tecnologías de la información y la comunicación (TIC) suelen asociarse al entretenimiento; sin embargo, también pueden emplearse para obtener, organizar y analizar información relevante en el desarrollo de investigaciones eficientes. Este estudio tuvo como objetivo determinar la relación entre el uso de las TIC y las competencias investigativas en estudiantes universitarios de pregrado. Se realizó una investigación cuantitativa, de diseño no experimental, básica y de tipo correlacional transversal. La muestra estuvo compuesta por 62 estudiantes seleccionados mediante muestreo no probabilístico. Para la recolección de datos, se aplicaron dos encuestas con alta confiabilidad (? = 0.957 para el uso de las TIC y ? = 1.00 para competencias investigativas). Los resultados mostraron que el 52 % de los participantes presentó un nivel destacado en el uso de las TIC, mientras que el 60 % alcanzó un nivel totalmente adecuado en competencias investigativas. Se concluyó que existe una correlación moderada entre el uso de las TIC y las competencias investigativas, lo que evidencia la importancia de implementar estrategias que potencien el acceso a información adecuada y eficaz en la elaboración de trabajos investigativos
Ansiedad, autoestima y hábitos de estudio en relación al rendimiento académico en estudiantes universitarios
Authors: Quizinga Molina Ivonne Nohely , Márquez Caro Orlando Juan , Michca Maguiña Mary Hellen Mariela , Cóndor Surichaqui Eva Elsa
Published: January 2025

El estudio tuvo como objetivo determinar la relación de la ansiedad, la autoestima y los hábitos de estudio con el rendimiento académico de estudiantes universitarios. La investigación fue de enfoque cuantitativo, de tipo descriptivo y nivel correlacional causal, con una muestra de 130 estudiantes de una universidad en Lima. Los resultados revelaron que la ansiedad se presentó en un nivel bajo en el 36.9 % de los participantes, en un nivel medio en el 45.4 % y en un nivel alto en el 17.7 %. En cuanto a la autoestima, se observó un nivel bajo en el 28.5 %, un nivel medio en el 52.3 % y un nivel alto en el 19.2 %. Por otro lado, los hábitos de estudio se clasificaron en nivel bajo en el 19.2 %, nivel medio en el 53.8 % y nivel alto en el 26.9 %. Se concluyó que la ansiedad, la autoestima y los hábitos de estudio se relacionan significativamente con el rendimiento académico. Además, los hábitos de estudio mostraron una mayor correlación con el rendimiento académico (p = 0.000), seguidos por la autoestima (p = 0.009) y la ansiedad (p = 0.004)
Planeación estratégica y calidad de la educación en una universidad de Lima
Authors: Mosqueira Cueva Edgar Dino
Published: January 2025

En un contexto de cambios continuos, lograr una educación de calidad en las universidades requiere de una planeación estratégica efectiva para afrontar los retos de gestión. Este estudio tuvo como objetivo determinar la relación entre la planeación estratégica y la calidad de la educación en estudiantes de una universidad en Lima. Se empleó un enfoque cuantitativo con un diseño no experimental y corte transversal. La población consistió en 191 estudiantes, de los cuales se extrajo una muestra probabilística de 127. La técnica utilizada fue la encuesta, y se aplicaron cuestionarios para cada una de las variables. Los datos fueron procesados con el software IBM SPSS, y se utilizó la estadística inferencial de Rho de Spearman para determinar la relación entre las variables. Los resultados mostraron una correlación directa moderada (rs = 0,602; p = 0,000). Se concluye que, a mayor planeación estratégica, mayor es la calidad de la educación
Comprensión lectora en estudiantes de secundaria en Perú
Authors: Torres-Vega Elva Medalid
Published: January 2025

La lectura y la comprensión son habilidades fundamentales, si un estudiante no lee bien y tiene inconvenientes para comprender un texto, tendrá dificultades en sus aprendizajes. La presente investigación tuvo como objetivo determinar el nivel de comprensión lectora en los estudiantes del VI Ciclo de educación secundaria en una institución educativa pública del distrito El Agustino en el año 2022. El tipo de investigación fue básica, de diseño descriptivo no experimental. Se evaluó la comprensión lectora a 317 estudiantes a través de la prueba CompLEC que mide la recuperación de la información, la integración de la información y la reflexión. Los resultados obtenidos: los estudiantes llegaron a 72,2% en nivel bajo, 25,9% en nivel regular y el 1,9% en un nivel alto. Se concluye, la enseñanza remota, el uso de estrategias poco innovadoras para el desarrollo de la comprensión lectora han incidido en que se haya obtenidos estos resultados
Gender Differences in Olfactory Recognition: A Comparative Study of Odour Stick Tests in High School Students
Authors: Katayama Naomi
Published: January 2025

There are two types of olfactory testing methods that can be used for screening in Japan.Both methods test detection and recognition of 12 odors commonly found in Japan.It has also been reported that the detection and recognition abilities of the sense of smell gradually decline with age. It has also been noted that the results of odor tests tend to be poorer in male than in female as they get older, from their 40s onwards. However, odour tests are not often conducted on younger generations. Therefore, this study aimed to compare whether there are gender differences in odour tests in high school students.
After receiving an explanation of the study and signing a consent form, 114 high school students (47 boys and 67 girls) were given an odour test using odour sticks. Participants smelled 12 different odours and wrote the number of the option they thought was correct from six options (numbers 1 to 4 list various specific odors name, five indicates that the particular odour is unknown but that it smells like something, and number 6 indicates that it has no odour) in the answer box.
The olfactory test results of boys and girls students were compared using statistical methods (chi-square test).
As a result, there was no statistically significant difference between boys and girls high school students who could recognize six or more of the 12 odours familiar to Japanese people (P=0.482). However, when the results of each odour were analyzed separately, boys students recognized statistically significantly fewer doors than girls students for the odours of India ink (P=0.031*), mandarin orange (P=0.0001**), and roasted garlic (P=0.047*). The sense of smell develops little by little from infancy, peaking in the teens, and then gradually declines. Therefore, testing teenagers’ olfactory perception abilities is important. From these results, we believe it is necessary to check the smells individually, not just to count the number of correct answers. We also believe that more data is needed to see the difference in olfactory recognition between boy (male) and girl (female).
Платежеспособность населения как показатель экономической доступности продовольствия на региональных продовольственных рынках
Authors: Абдурахманова Л.С. , Гасанов И.М. , Жамолатова З.Н. , Магомедова М.А.
Published: January 2025

Характеризуя продовольственное обеспечение как систему и процесс на уровне региона важно проанализировать платежеспособность населения, а также структуру расходов населения на продовольственные товары и предпочтения его в ассортименте, ценовую доступность продовольствия.
Учетная политика бюджетных организаций: особенности формирования и принятия
Authors: Хамзатов В.А. , Абубакиров Ш.Р. , Дииева М.М.
Published: January 2025

в статье рассмотрены вопросы формирования учетной политики бюджетных организаций. Выделены варианты формирования учетной политики. Обозначены типичные ошибки, которые допускаются при формировании учетной политики. Определены объекты учета, по которым допускается вариантность учет и оценки. Отмечено, что положения учетной политики не должны дублировать вопросы, которые однозначно определены в нормативно-правовых актах, регулирующих ведение учета в бюджетных организациях.

the article considers the formation of accounting policies of budgetary organizations. The options for the formation of accounting policies are highlighted. Typical errors that are allowed in the formation of accounting policies are indicated. The objects of accounting are determined for which accounting and valuation variations are allowed. It is noted that the provisions of the accounting policy should not duplicate issues that are uniquely defined in the regulatory legal acts governing accounting in budgetary organizations.
Автоматизация учета готовой продукции и ее продажи в сельском хозяйстве
Authors: Горбунова Е.Е. , Никулина С.Н. , Бутюгина А.А.
Published: January 2025

В современных условиях необходимо постоянно совершенствовать информационные технологии организации. Особое внимание в статье уделяется автоматизации учета готовой продукции и ее продажи.

In modern conditions, it is necessary to constantly improve the information technology of the organization. Particular attention is paid to the automation of accounting of finished products and its sale.
«Подрывные» и «поддерживающие» нововведения и их роль в современной экономике
Authors: Крюкова А.А. , Беляева А.В.
Published: January 2025

Статья посвящена подрывным и поддерживающим инновациями их влиянию на экономику. Выявлены отличительные особенности данных типов инноваций. Рассмотрены ключевые примеры нововведений каждого типа.

The article is devoted to disruptive and supportive innovations and their impact on the economy. Distinctive features of these types of innovations are revealed. The key examples of innovations of each type are considered.
Проблемы контроля расчетов по налогу на доходы физических лиц
Authors: Заволокина Д.О.
Published: January 2025

В статье рассматривается актуальная проблема контроля расчетов по налогу на доходы физических лиц. Обсуждается многосложность системы функционирования подоходного налогообложения и значимость ее социально-экономического баланса. Особое внимание уделено вопросу по контролю всех поступлений на карты физических лиц со стороны федеральной налоговой службы. Рассмотрены обязанности и действия данного надзорного органа по отношению к поступлениям финансовых средств на банковские карты физического лица. Приведены рекомендации для физических лиц по управлению своими финансовыми средствами в рамках нынешнего налогового законодательства.

The article deals with the actual problem of controlling calculations for the tax on personal income. The complexity of the income taxation system and the significance of its social and economic balance are discussed. Particular attention is paid to the issue of controlling all receipts on the cards of individuals from the federal tax service. The duties and actions of this supervisory authority in relation to the receipt of funds on bank cards of an individual are considered. Provides recommendations for individuals to manage their financial assets under the current tax legislation.
Финансовое состояние предприятия как показательего рыночной устойчивости
Authors: Магомадов М.Х. , Хабилаев Д.Х. , Агиева Ф.Я.
Published: January 2025

в статье определены факторы, влияющие на финансовую устойчивость предприятия. Выделена роль анализа финансового состояния организации и обозначены его задачи. Дана характеристика инвестиционной привлекательности хозяйствующего субъекта. Обосновано значение уровня платежеспособности организации, приведены показатели, отражающие его уровень. Отмечена необходимость анализа кредитоспособности, как значимого показателя финансового состояния предприятия

the article identifies factors affecting the financial stability of the enterprise. The role of the analysis of the financial condition of the organization is highlighted and its objectives are identified. The characteristic of investment attractiveness of an economic entity is given. The value of the organizations solvency level is substantiated, indicators reflecting its level are given. The need for analysis of creditworthiness as a significant indicator of the financial condition of the enterprise
Информационно-аналитическое обеспечение процесса управления платежеспособностью и ликвидностью организации по данным финансовой отчетности
Authors: Пайтаева К.Т. , Делаева Л.У. , Эбазуева Ф.С. , Хасиева А.С.
Published: January 2025

В данной статье определено значение бухгалтерской (финансовой) отчетности для оценки финансовой деятельности предприятия. Раскрыта сущность показателей платежеспособности и ликвидности, характеризующих финансовое положение предприятия. Охарактеризовано информационно-аналитическое обеспечение процесса управления платежеспособностью и ликвидностью организации по данным финансовой отчетности.

This article defines the value of accounting (financial) statements for the evaluation of the financial activities of the enterprise. The essence of solvency and liquidity indicators characterizing the financial position of the enterprise is revealed. Information and analytical support of the process of management of solvency and liquidity of the organization according to the financial statements is characterized.
Организация бухгалтерского учета на малых предприятиях
Authors: Яричев Д.А.
Published: January 2025

В данной статье рассматриваются актуальные вопросы организации бухгалтерского учета на малых предприятиях. Представлена система регулирования бухгалтерского учета в Российской Федерации. Охарактеризованы особенности налогообложения малых предприятий.

This article discusses the current issues of accounting in small enterprises. The system of accounting regulation in the Russian Federation is presented. The peculiarities of taxation of small enterprises are characterized.
Взаимодействие между ERP-II, цепочками поставок и эксплуатационными характеристиками производства
Authors: Хасаншина Л.И.
Published: January 2025

ERP-IIявляется важным инструментом для управления потоком как внутри, так и за пределами процессов компании. Чтобы удовлетворить координацию между отделами и подрядчиками, ERP-IIобеспечивает контроль материальных и информационных потоков, используя различные модули, включая цепочку поставок, производство и управление складом. Целью данной статьи является изучение взаимодействия между планированием ресурсов предприятия (ERP-II), организацией цепочек поставок (SCO) и операционной производительностью (OPER) путем формирования макроперспективы, основанной на научном фундаменте Resource-Based View (RBV). Enterprise Resource Planning (ERP-II) предлагает структуру, которая реконструирует процессы предприятий. Необходимо сосредоточить внимание на влиянии практик ERP-II, опосредованных SCO, на операционные показатели путем сравнения их прямых эффектов, особенно с точки зрения реализации цепочек поставок для производственных компаний.

ERP-II is an important tool for managing flow both inside and outside the companys processes. To satisfy coordination between departments and contractors, ERP-II provides control of material and information flows using various modules, including the supply chain, production and warehouse management. The purpose of this article is to study the interaction between enterprise resource planning (ERP-II), supply chain organization (SCO) and operational performance (OPER) by creating a macro perspective based on the scientific foundation of Resource-Based View (RBV). Enterprise Resource Planning (ERP-II) offers a structure that revolutionizes enterprise processes. It is necessary to focus on the impact of SCO-mediated ERP-II practices on operational performance by comparing their direct effects, especially in terms of supply chain implementation for manufacturing companies.
Модель интеграции адаптивного алгоритма выбора и смены консенсуса блокчейна при граничных значениях показателей сети
Authors: Помогалова А.В. , Донсков Е.А. , Елагин В.С.
Published: January 2025

Рассматривается математическое описание адаптивного алгоритма выбора и смены консенсуса блокчейн-сети при наступлении определенных сетевых условий. Представлен анализ структуры пакета, содержащего трафик блокчейн-сети, а также выполнен расчет средней сетевой нагрузки при передаче блоков транзакций по сети. В работе приводятся граничные значения показателей сети, а также наиболее эффективные алгоритмы консенсуса для обеспечения бесперебойной обработки транзакций в различных сетевых условиях. Представлены результаты аналитических расчетов и экспериментального моделирования, демонстрирующие эффективность предлагаемого подхода.

The paper considers a mathematical description of the model of an adaptive algorithm for selecting and changing the consensus of a blockchain network when certain network conditions occur. The paper presents an analysis of the structure of a packet containing blockchain network traffic, as well as a calculation of the average network load when transmitting transaction blocks over the network. The paper provides boundary values of network indicators, as well as the most effective consensus algorithms for ensuring uninterrupted transaction processing in various network conditions. The results of analytical calculations and experimental modeling are presented, demonstrating the effectiveness of the proposed approach.
Разработка автоматического портативного электроэнцефалографа с возможностью интегрирования в Единую информационную систему Арктической зоны РФ
Authors: Степанов А.Б.
Published: January 2025

Работа посвящена разработке концепции Единой информационной системы (ЕИС) Арктической зоны Российской Федерации и разработке автоматического портативного электроэнцефалографа с возможностью интегрирования в данную систему. Приводятся предложенные автором математические модели вейвлетов для непрерывного вейвлет-преобразования, адаптированные к анализу электроэнцефалограммы, и двухэтапная система анализа электроэнцефалограммы, позволяющая выявлять около 80% артефактов и патологических составляющих в сигнале. Приводятся результаты испытания прототипа автоматического портативного электроэнцефалографа и элементов ЕИС Арктической зоны РФ.

The paper is devoted to developing the concept of the Unified Information System of the Arctic Zone of the Russian Federation and designing an automatic portable electroencephalograph with the possibility of integration into this system. The author proposes mathematical models of wavelets for continuous wavelet transform adapted to the analysis of an electroencephalogram and presents a two-stage system of electroencephalogram analysis, which allows identifying about 80% of artifacts and pathological components in the signal. The paper also provides the results of testing the prototype of an automatic portable electroencephalograph and elements of the Unified Information System of the Arctic Zone of the Russian Federation.
Метод обнаружения WLAN точек доступа нарушителя в распределенной ИСПДн
Authors: Ковцур М.М. , Сахаров Д.В. , Бирих Э.В. , Дрепа В.Е.
Published: January 2025

Разработан метод автоматизированного обнаружения и блокировки WLAN точек доступа нарушителя в распределенной информационной системе персональных данных (ИСПДн), позволяющий сократить время реагирования и ликвидации последствий компьютерного инцидента, вызванного установкой точки доступа нарушителя. Проведена расчетная оценка и экспериментальная проверка эффективности работы предложенного метода. Разработанный подход представлен в виде алгоритма, способного автоматически выявлять точки доступа нарушителя, подключенные в корпоративную инфраструктуру, и оперативно отключать их.

A method is developed for automated detection and blocking of intruder access points in a distributed personal data information system, which allows reducing the response time and eliminating the consequences of a computer incident caused by the installation of an intruder access point. A computational assessment and experimental verification of the efficiency of the proposed method were carried out. The developed approach is presented in the form of an algorithm capable of automatically identifying intruder access points connected to the corporate infrastructure and promptly disabling them.
EPIDEMIOLOGY AND STRUCTURING OF JAW CYSTS IN CHILDREN
Authors: Ododiuk V.V.
Published: January 2025

The article provides information about a study to learn epidemiology and structuring of jaw cysts in children conducted to improve the approach to diagnosis, treatment selection, and patient management. A retrospective analysis of 287 case histories of patients with jaw cysts aged 4 to 17 years was conducted. The study showed that the most common cystic lesion of the jaws in children is radicular and radicular odontoid cyst, which are diagnosed more often in boys than in girls, aged 8-11 years with localization on the lower jaw. The causal teeth for the development of radicular, radicular tooth-containing cysts are temporary molars, which were treated in 50% of cases. Clinical manifestations of cysts of any origin in half of the cases of all cysts were only deformation and thinning of the cortical plate against the background of unchanged mucosa.

Məqalədə çənə sistalarının diaqnostikasını, müalicə seçimini və xəstələrə yanaşılmanı təkmilləşdirmək üçün onların epidemiologiyasını və strukturizasiyasını öyrənmək məqsədilə aparılmış tədqiqat işi haqqında məlumat verilmişdir. Çənə sistası olan və yaşı 4-dən 17-yə qədər olan 287 xəstənin xəstəlik tarixlərinin retrospektiv təhlili aparılmışdır. Tədqiqat göstərmişdir ki, uşaqlarda çənələrin ən çox rast qəlinən sistalarına radikulyar və radikulyar-diş sistaları aiddir. 8-11 yaşlar arasında olan qızlara nisbətən eyni yaşlı oğlanlarda daha çox rast gəlinir və onlarda sistalar çox vaxt alt çənədə lokalizasiya edir. Radikulyar və radikulyar-diş tərkibli kistaların yaranmasına səbəb olan dişlər 50 % hallarda müalicə edilmiş azı dişlərdir; mənşəyindən asılı olmayaraq bütün sistaların klinik təzahürləri xəstələrin 50% qədərində selikli qişada yalnız kortikal lövhənin deformasiyası və nazikləşməsi şəklində təzahür edir.

В статье представлены результаты исследования, проведенного с целью изучить и структурировать кисты челюстей у детей с целью улучшения подхода к диагностике, выбору лечения и ведению пациентов. Проведен ретроспективный анализ 287 историй болезни пациентов с кистами челюстей в возрасте от 4 до 17 лет. Исследование показало, что наиболее распространенным кистозным поражением челюстей у детей является радикулярная и радикулярная-зубосодержащая киста, которые диагностируются чаще у мальчиков, чем у девочек, в возрасте 8-11 лет с локализацией на нижней челюсти. Причинными зубами развития радикулярных, радикулярных-зубосодержащих кист являются временные моляры, которые в 50% случаев лечились. Клиническими проявлениями кист любого происхождения в половине случаев всех кист регистрировалась только деформация и утонченность кортикальной пластинки на фоне неизмененной слизистой.
İRSİ FRUKTOZAYA QARŞI DÖZÜLMƏZLİK SİNDROMU: KLİNİK MÜŞAHİDƏ
Authors: Hacıyeva N.N. , Sultanova N.H. , Süleymanlı A.A. , Tağıyev A.Y. , Bayramov B.İ. , Quliyeva L.M.
Published: January 2025

Məqalədə fərqli yaşlarda fruktozaya qarşı dözülməzlik sindromu (FDS) diaqnozu təsdiqlənən 3 pasiyent haqqında məlumat verilib. İrsi fruktozaya dözülməzlik sindromu (FDS) – 9-cu xromosomun q 22.3. lokusunda yerləşən aldolaza B zülalını kodlaşdıran ALDOB genin mutasiyası nəticəsində törənir. Xəstəlik, fruktoza qəbulundan sonra bir sıra ciddi əlamətlərlə xarakterizə olunan irsi metabolik pozuntu şəklində təzahür edir. Aldolaza B çatışmazlığı olan orqanizmdə fruktoza-1-fosfat toplanaraq toksik təsir göstərir. Bunun nəticəsində ürəkbulanma, qusma, hipoqlikemiya, metabolik asidoz, qaraciyər və böyrək funksiyalarının pozulması müşahidə edilir; xəstəlik ağır hallarda letallıqla nəticələnə bilir. Ana südünün tərkibində fruktoza olmadığına görə xəstəlik uşaqları əlavə qidaya keçirildikdə və ya tərkibində fruktoza olan qida maddələri qəbul etdikdən sonra üzə çıxır.

В статье описаны 3 пациента разного возраста с диагнозом наследственной непереносимости фруктозы. Наследственная болезнь непереносимости фруктозы (IFIX) – 9q22.3 выявляется в результате мутации гена ALDOB, кодирующего альдолазу В, расположенного на хромосоме. Это наследственное заболевание обмена веществ, характеризующееся рядом серьезных симптомов после приема фруктозы. В организме, лишенном альдолазы В, F-1F накапливается и оказывает токсическое действие. В результате такого токсического воздействия возникают тошнота, рвота, гипогликемия, метаболический ацидоз, нарушение функций печени и почек, а в тяжелых случаях могут привести к летальному исходу. Поскольку материнское молоко не содержит фруктозы, заболевание появляется при переходе детей на прикорм или после употребления продуктов, содержащих фруктозу.

The article provides information about three patients diagnosed with hereditary fructose intolerance syndrome (FIS) at different ages. Hereditary fructose intolerance syndrome (FIS) results from a mutation in the ALDOB gene, which encodes the aldolase B protein located on chromosome 9q22.3. The disease manifests as a hereditary metabolic disorder characterized by severe symptoms after fructose intake. In individuals with aldolase B deficiency, fructose-1-phosphate accumulates, causing toxic effects. As a result of this toxicity, symptoms such as nausea, vomiting, hypoglycemia, metabolic acidosis, and impaired liver and kidney function are observed; in severe cases, the disease may lead to fatal outcomes. Since breast milk does not contain fructose, the disease typically presents when the child is introduced to supplementary food or consumes foods containing fructose.