bluuebunny/crossref_metadata_2025 huggingface dataset:
The philosophical and theological content, the symbolism of the Holy Cross in Ancient Rus and the Sacred History
Authors: Bondar Stanislav V.
Published: December 2019

Each professional researcher of the religious and philosophical tradition of Ukraine XI-XIV centuries. convinced of the glow of theoretical understanding of the manuscript corpus of texts of a certain period, realizes that 90% of the monuments of that time are waiting for study, knows that the subject-based, scientific sources are aimed at reconstructing how the beginning and the end were presented, stages, goals , the factors, essence and meaning of world history in the culture of are still in the embryonic phase, and the problem of understanding the role of the Holy Cross in the historical process has not been raised or analyzed yet by the bearers of this culture. These facts lead to an attempt to fill the existing lacuna.
Oriental rite as a religious phenomenon
Authors: Buhrak Volodymyr
Published: December 2019

The phenomenon of Eastern Christian rite has become an object of religious studies in recent years. This phenomenon is of interest to the scientific community because it is the result of the development of theological concepts, which, being theoretically expressed in collections of Christian dogmas and canons, have found their practical reflection in cultic church and extracurricular activities. Some historical events have been found in it. Investigating the rite, we can trace the peculiarities of the development of society, the reflection of a certain era.
Religion in the structure of spiritual values
Authors: Vasilyeva Olena S.
Published: December 2019

Religion is an important factor in the social interaction of people, which can significantly determine the direction of social development. As a spiritual phenomenon, religion is directly related to man, with his attachment to high spiritual ideals.
Psychological aspects of the functioning of religious values (Christian aspect)
Authors: Pyrog Ganna V.
Published: December 2019

The relevance of the study of the problem of Christian axiology is due to the growing interest in religion and the associated change in world outlook and values ​​in contemporary Ukrainian society. The study of religious values ​​is caused by the urgent problem of finding universal moral values ​​of social development and clarifying the content, structure and nature of their functioning. However, all the basic principles of Christian doctrine acquire character of value only in the presence of subjective attitude, their personal importance for the believing individual. Only in this way can religious values ​​influence the motivation of actions and determine human behavior.
From the history of the emergence and development of Adventism in the XIX century.
Authors: Sitarchuk Roman A.
Published: December 2019

This article is about an early period in the history of Adventism as a future world-class denomination. The activity of the most famous theologian scientists whose works influenced the formation of the foundations of Adventist doctrine is depicted. The formation of the organizational structure of Adventists in North America, as well as in other continents, is being scrutinized.
The ghost is wandering in Ukraine, the ghost of plagiarism… (review of Ya.Chernenky's textbook "Religious Studies: Theoretical and Practical Course")
Authors: Sarapin Oleksandr V.
Published: December 2019

In recent years many textbooks and manuals on religious studies have been published in Ukraine. However, one of them deserves special attention because of the frank and even brazen appropriation of the author by the author of the meaningful potential not only of national scholars but also of the classics of world religious studies. It is a textbook of Ya.Chernenko's "Religious Studies: A Theoretical and Practical Course", which was published in 2005 in the Kiev publishing house "Professional" with a circulation of 800 copies. I would like to point out that this guide was recommended by the Ministry of Education and Science of Ukraine for higher education students (letter No. 14 / 18.2 - 2835 of December 28, 2004).
Note to the authors
Authors: Of the Journal Editorial board
Published: December 2019

Note to the authors
The development of railway transport engineering in the Russian Empire in the second half of the nineteenth century
Authors: Hurinchuk Svitlana
Published: December 2019

The article is devoted to the consideration of the features on the development of railways and railway engineering in the second half of the ХІХ th century. It is well known that railway transport in European countries emerged in the eighteenth century, and the nineteenth century was a period of rapid development of raiway systems, railway technology and the creation of operation technologies. The author of the article shows that the development of railway transport engineering in the Russian Empire began in the 30s of the XIX century and went on at a rapid pace. It is clear that foreign technology was used at first, and foreign technology thought was significantly influenced by technology. As the whole policy of the tsarist government was aimed at reducing the country’s dependence on potential opponents, the idea of forming a Corps of national transport engineers was greatly supported. Among its graduates were such well-known engineers as P. P. Melnykov, M. I. Lypyn, V. P. Sobolevskyi, M. A. Beleliubskyi, D. I. Zhuravskyi and others who managed to create a national scientific school in the field of railway transport. Almost all problems were solved independently without the help of foreign specialists. Among them, according to the author, the most significant were “Track bed structure”, “The development of signalling systems, centralization and block signal system” and “The development of rolling stock”. Based on the analysis of a large number of sources, the author concludes, that in the second half of the nineteenth century the development of industry in the Russian Empire went through capitalist reforms. Expansion of domestic and foreign markets, active domestic and foreign trade led to the need to develop means of communication. The railways proved to be the most powerful and economically effective. They connected different regions, places of production and consumption, facilitating, speeding up and reducing the cost of delivery of raw materials and goods. In the 60-80’s of the XIX century there was a significant increase of the railway network. The construction was mainly carried out at the expense of private joint stock companies. During that period, foreign specialists who were not interested in the qualitative development of the Russian railway network played a major role in the construction and management of the railway tracks. With the increasing demand for this new type of transportation, there was a need for technical modernization of the entire industry.
Melatonin and brown adipose tissue: novel insights to a complex interplay
Authors: Olesçuck Ingrid Fernandes , Camargo Ludmilla Scodeler , Carvalho Paula Vargas Versignassi , Souza Caroline Aparecida Pereira , Gallo Camila Congentino , Amaral Fernanda Gaspar do
Published: December 2019

As a chronobiotic molecule, melatonin finely tunes a variety of physiological

processes including energy metabolism, reproduction and sleep-wake cycle, collaborating

for the survival of the organisms. Since its pineal production occurs

exclusively during the night, melatonin is responsible for signaling the

circadian and circannual cycles to the organisms. This involves different ways

of action that need to be considered when analyzing its effects in a given

tissue/organism. Non-shivering thermogenesis (NST) is a crucial process for

homeothermic animals and increasing evidences show its importance for the

energy metabolic balance due to its influence in body weight control. The

highly seasonal brown adipose tissue (BAT) is the site for NST and its

metabolism is importantly influenced by melatonin. This review focuses on

melatonin actions over BAT and the attention should be given to the relation

between this signaling molecule and such a seasonally expressed tissue.
Prospects for the development of innovative nano- and biotechnologies
Authors: Bielikova Nadiia , Yaroshenko Ivan
Published: December 2019

Nano- and biotechnologies are the key elements of the complex of NBIC-technologies, developed within the concept of continuous growth of innovations in the context of the transition to the sixth technological mode. The purpose of the article is to study the prospects for the development of nano- and biotechnologies in various sectors of the economy, as well as explore opportunities for accelerating the commercialization of research results in these areas. The article’s relevance is confirmed by the strengthening of the role of nano- and biotechnologies in the sphere of innovation development of countries worldwide. The results of the study have shown that the nanotechnology market has a divergent structure, and the basic characteristic of nanoproducts is their interdisciplinary nature. The world leaders in the production and commercialization of nanotechnologies are the United States, China, Japan, Germany and South Korea. Biotechnologies are developing rapidly as well. Worldwide, the largest number of biotechnologies is created in areas such as health care (biomedicine and biopharmaceuticals), industry and agriculture. The leading countries in the field of development and commercialization of biotechnologies are the United States, France, Germany and South Korea.
Prospects of convergent technologies usage in solving the global energy problem
Authors: Matyushenko Igor , Azarenkova Olesia
Published: December 2019

The article summarizes the main findings regarding a study on global problems, with an emphasis on global energy problems and possible solutions. To find solutions to global problems, the conditions of the new industrial revolution were taken into account, the features of technological development of economies in countries worldwide were investigated and, namely the essence of economic paradigms aimed at solving global problems was determined. Convergence of NBIC-technologies as a key factor of the new industrial revolution were characterized, and the process of converging knowledge, technologies and society as a mechanism for solving global problems was studied. Trends in the development of scientific and technical, innovative activities in Ukraine and countries worldwide were determined. In particular, the main directions for development of converging and advanced production technologies that are most promising for developed countries, developing countries and Ukraine are presented.
Sistem Monitoring Pelanggaran Siswa Berbasis Web
Authors: Saputra Haris Tri , Dawolo Aniria , Zulafwan Zulafwan
Published: December 2019

This study aims to build an application that serves to monitor violations committed by students on the research object, namely SMA Negeri 10 Pekanbaru State High School, the appointment of the title of this study is based on the found cases where parents do not know the violations committed by their children at school, because each violation has points assessment and if the research points have reached the maximum value, parents will be summoned, from information obtained from the school, parents will feel disappointed if they are called to school because their children have committed many violations, therefore an application is built so that parents can monitor the extent of their children violating. the application is built based on the web so that it can be accessed anytime and anywhere, the method of software development uses the waterfall method, the design is done using UML diagrams for modeling the application.
Peningkatan Keamanan Website Menggunakan Metode XML dengan Framework Codeigniter
Authors: Nur Rofil M , Na'am Jufriadif , Nurcahyo Gunadi Widi , Arlis Syafri
Published: December 2019

Website security is needed in the dissemination of every information and data in cyberspace now. On the previous website the security used was not optimal in securing the website so we needed a reliable website security. XML (eXtensible Markup Language) is a markup language that is designed to store and deliver data by forming its own tags as needed. Codeigniter Framework is a php framework that is open source and uses the MVC method (Model, View, Controller). codeigniter is free or not paid if you use it. Codeigniter framework is made with the same purpose as other frameworks, namely to facilitate developers or programmers in building a web-based application without having to create it from scratch. The results of testing of this method are able to help and minimize the entry of hackers and secure data that will later become information. Using this method of combining can safeguard the entry of hackers and help secure the data and information on the website.
KNOWLEDGE, MOTIVATION, TRAINING AMONG VOLUNTEER COMMUNITY HEALTH WORKERS
Authors: Farich Achmad , Kusumaningsih Dewi , Seprianti Sosya Mona
Published: December 2019

Background: Integrated Service Post (Posyandu) is one form of community based health efforts which is managed and implemented by volunteer community health workers. That performance is very important to monitor the toddlers. The coverage of toddlers weighed at Ngaras at public health Service has decreased by 2014 reached of 87.0% in 2015 reached of 100.4% in 2016 reached of 64.0% but in 2017 it only reached of 68,2%.Purpose: To know the correlation of knowledge, motivation, training among volunteer community health workers at public health services West Pesisir Province of Lampung  2018.Methods: Quantitative research type with cross sectional design and population recruited  all of volunteer community health workers. Data collected by using questionnaire sheets. Analysis of data used univariate and bivariate (Chi Square).Results: The results showed that the volunteer community health workers have best performance with number of 45 volunteers (69,2%) comparing with who has a poor performance with number of 20 volunteer (30,8%). Based on bivariate analysis following in several parts of the volunteer such as knowledge with  p-value of 0,001 OR 4,889 (1,5 to 15,3 95% CI), motivation with p-value 0,034 OR 3,778 (1,2 to 11,4 95% CI), and the training with p-value 0,009 OR 5,429 (1,6 to 17,8 95% CI).Conclusion: There is a relation of knowledge, motivation and training for the performance of volunteer community health workers. It is suggested to management of public health centre on Ngaras to conduct more intensive training related to volunteer training which includes knowledge sharing which will improve on volunteer community health workers performance on task, and motivation to intensify duty of passion of volunteer community health workers
THE FAMILY MENTORING PROGRAM (FMP) ON IMPROVEMENT OF NUTRITIONAL STATUS
Authors: Shalahuddin Iwan , Eriyani Theresia , Riyanti Riyanti
Published: December 2019

Background: Cases of poor nutritional status in toddlers can be found in families that are materially classified as rich, this is due to clean and healthy living behavior that is not in accordance with health standards. In Girimukti Village, Cibatu Health Center, Garut Regency, the majority condition of the education is in low level and only 1591 (32%) of 5569 patriarch had passed Junior High School, and has income in low level, between 300 - 500 thousand (IDR) per month.Purpose: Knowing The effect of family mentoring program (FMP) on improvement of nutritional statusMethods: The type of this study was quasi experimental with pretest, posttest and control design with pretest-posttest quasi experimental design. The study sample was carried out using stratified random sampling with a population of malnourished mothers and under-fives for the Girimukti village area, the working area of Cibatu Community Health Center was 61 people.Results: Statistical test results with a confidence level of 95% showed that there were changes in parents' knowledge about nutrition. The average change in calorie intake consumed by toddlers in the treatment group reached 6.92% of the original calorie intake and the average change in calorie intake consumed in the control group reached 2.10% of the original calorie intake. The results of statistical tests show that there are significant differences in the average changes in calorie intake consumed by toddlers between the treatment group and the control group (p <0.05).Conclusion: From the results of the study it can be concluded that the knowledge and attitudes of mothers of children under five who received family nursing care by students were better than mothers who did not receive family nursing care.
TYPE 2 DIABETES MELLITUS ON TRIGLYCERIDE LEVELS AND BLOOD PRESSURE
Authors: Anggorotomo Wirawan , Sjahriani Tessa , Masroni Masroni
Published: December 2019

Background: Diabetes Mellitus (DM) is a group of metabolic diseases characterized by an abnormality of insulin secretion, insulin work, or both. DM cases in Indonesia as many as 8,5 million cases in 2013. Prevalence based on diagnosis or symptoms according to the health departement of 2,1%.Purpose: To know the correlation of type 2 diabetes mellitus on triglyceride levels and blood pressureMethods: This study used secondary data derived from the medical record status of patients with diabetes mellitus. The method used is analytic observational with cross sectional approach. Sampling technique using purposive sampling. The population of this study is the diabetes mellitus type 2 in 2017 as many as 151. Sample of 109 respondents. Data analyzed by univariate and bivariate using Chi Square analysis.Results: The frequency of respondent characteristic on female gender as much 57,8%, based on age group >45 old counted 58,7%. Blood pressure frequency distribution found hypertension as much 63,3%. High frequency distribution of triglyceride levels is 67,9%. The Chi Square analysis result there is a significant correlation of type 2 diabetes mellitus on triglyceride levels and blood pressure with Odds Ratio 6,865 with p-value of 0,009.
CONGESTIVE HEART FAILURE SELF‐MANAGEMENT EDUCATION AND READMISSION AFTER HOSPITALIZATION
Authors: Hidayah Nurul , Wahyuningtyas Eka Sakti , Shalahuddin Iwan
Published: December 2019

Background: Congestive Heart Failure (CHF) is a condition where the heart can no longer pump blood to the body tissues either to the entire body (systemic circulation) or to the lungs (pulmonary circulation). CHF is a clinical syndrome in patients with structural abnormalities and heart function. Heart function impairment may be a systolic or diastolic function disorder, heart rhythm disturbance, or preload and after load mismatch. This condition can cause death to the patient. Deaths from CHF range from 20-50% per year, in addition CHF is a disease that requires readmission . Frequency of CHF patient readmission  by 45% per year.Purpose: This study aims to analyze the relationship of congestive heart failure self‐management education and readmission after hospitalizationMethods: The study was conducted at ICCU Tidar Magelang hospital with 27 CHF patients who had readmission. The sampling technique was done by consecutive sampling technique. Data analysis in this study using Chi square. The result of statistical test (Chi Square) shows that 2 cells (50%) with expected value <5 means the cells (boxes) whose expected value is below 5 by 50%. The minimum expected value of 2.07 means no expected value <1. Continuity Correction with p = 0,000. Fisher's Exact Test p value = 0,000.Resuts: The results of Symmetric Measure table (correlation test) obtained by the value of Contingency Coefficient (r) = 0.674 with p = 0,000.Conclusion: The conclusion of this statistical test is that there is a correlation between Experience of Self-Management Education (SME)  and readmission  of CHF patients.
BODY MASS INDEX AND ANXIETY IN POSTPARTUM PERIOD
Authors: Narulita Sari , Yuria Mella , Istianah Isti
Published: December 2019

Background: The period of pregnancy and postpartum is the period when hormonal imbalance and adjustment become a mother (social factor) that makes a woman transition both physically and psychologically. Physically, the phases of pregnancy and postpartum greatly contribute to the increasing rate of obesity in women.Purpose: This study aims to analyze the relationship between body mass index and postpartum women's anxiety level in Sukabumi City in 2014.Methods: This research type is survey research using Cross Sectional method. The target population of the study was women who underwent labor in Sukabumi city of West Java with a sample of 97 people using random sampling technique.Results: From the analysis of the relationship between body mass index and postpartum anxiety level there was a significant relationship. From the results of analysis of body mass index relationship with mild anxiety level and moderate-severe anxiety there is no significant relationship.Discussion: The need to provide counseling about preparing before pregnancy or before birth in women. So that women are ready physically and mentally in pregnancy and labor so that it can reduce the number of anxiety disorders in postpartum women.
EFFECTIVENESS OF JASMINE OIL (JASMINUM OFFICINALE) MASSAGE ON REDUCTION OF LABOR PAIN AMONG PRIMIGRAVIDA MOTHERS
Authors: Mukhlis Hamid , Nurhayati Nurhayati , Wandini Riska
Published: December 2019

Background: Intolerable labor pain encourages maternal use of painkillers such as analgesics and sedatives while these drugs have side effects on the mother and fetus.Methods: Quantitative research by using a quasi-experimental approach with one group pretest posttest. The population in this study was maternity during the phase I active with sample  was 20 respondents. The study conducted on March 2018 at Teluk Pandan, Pesawaran, Lampung-Indonesia.Results: The Effectiveness of counter pressure massage using jasmine oil (jasminum officinale) in reducing delivery pain with p-value 0,000Discussion: The positively significant alteration in delivery pain score after therapySuggestions: That therapy could be alternative to help in reducing delivery pain.
THE EFFECTS OF WARM COMPRESS TO VOIDING REFLEXES ON POST OPERATIVE SPINAL ANESTHESIA
Authors: Djamaludin Djunizar , Amila Amila , Asianti Suci
Published: December 2019

Background: Spinal anesthesia commonly can lead to urinary retention because the patient cannot feel his bladder is full and unable to initiate for voiding after the surgery. This is caused by bladder and sphincter muscles are unable to respond for voiding reflexes. One of nursing intervention to prevent of urinary retention is warm compress on supra pubic area for postoperative patient undergo spinal anesthesia.Purpose : This study was to examinethe effect of warm compress to recovery of voiding reflexes ont postoperativepatient undergo spinal anesthesia at Pertamina Bintang Amin Hospital, Bandar LampungMethods : A quasiexperimental study was conducted usingintervention and control groups with simple random sampling technique was applied. There were 30 postoperative patientsundergo spinal anesthesia were recruited at Pertamina Bintang Amin Hospital Bandar Lampung.Result : The mean score of intervention group with warm compression was 6.67 hours (ranging from 6to 8). The mean score of control group withoutwarm compress was7.13 hours (ranging from 5t o 9).Conclusion: Nursing intervention by applying warm compress is necessary to recovery of voiding reflex on postoperative patient with spinal anesthesia.
CHARACTERISTICS OF LYMPHADENITIS IN HOSPITALISED PATIENTS BANDAR LAMPUNG-INDONESIA
Authors: Rusmini Hetti , Ariza Retno , Sari Nur Rahayu Permana
Published: December 2019

Background: Lymphadenitis is an inflammation of the lymph nodes caused by a variety of microorganisms such as Mycobacterium tuberculosis, human immunodeficiency virus (HIV), and other microorganisms. Patient characteristics lymphadenitis diverse views on the etiology, age, gender, and lymph nodes affected.Purpose: The purpose of this study was to describe the characteristics of patients with lymphadenitis.Methods: The design of this study is descriptive cross sectional method is done by looking at medical records of patients in Dr. H. Abdul Moeloek hospital Bandar Lampung 2015. The samples were taken using stratified random sampling technique so that 161 samples used in this study.Results: The results showed the frequency distribution of patients with tuberculous lymphadenitis is the highest (57.14%), lymphadenitis other microorganisms (21.74%), and HIV lymphadenitis (21.12%). The frequency distribution of TB lymphadenitis patient age was 15-24 years (45.7%), patients with HIV lymphadenitis most at the age of 45-64 (29.4%), while the age of the patient lymphadenitis other microorganisms highest in the 15-24 age (28 , 6%). The frequency distribution of TB lymphadenitis gender, HIV and most were female (58.7% and 52.9%), while the frequency distribution of the sexes in most other microorganisms lymphadenitis patients were male (54.3%).Conclusion: The frequency distribution locations lymphadenitis TB, HIV and other microorganisms most was the neck (regio colli) (96%, 55.9% and 57.1%).
Determinants of roundworms among primary school students in North Sumatera Province, Indonesia
Authors: Girsang Vierto Irennius , Manik Friska Vaulina , Munthe Seri Asnawati
Published: December 2019

Background: Worm infection was an environment-based disease caused by nematode class worms’ intestine and transmitted through the soil. This condition could effect to their ability in school-age children to pay attentiont during the lessons.Purpose: To determine the determinants of roundworms in elementary school students in Silahisabungan Subdistrict (Dairi) , North Sumatera, Indonesia.Methods: The case-control design with a total sample of 150 students taken from 5 elementary schools starting in grade 5 and 6. This research instrument used a questionnaire.Results: That there was no effect between hand washing habits at OR 1.90 (95% Cl: 0.697 - 5.180), there was no effect on nail hygiene by OR 1.19 (95% Cl: 0.505-2828), there was no the influence of footwear use amounting to OR 1.68 (95% Cl: 0.672-2225), there was an influence of the source of clean water of OR = 17.17 (95% Cl: 1,800-1 163,78) and there is an effect of providing latrines at OR = 5.55 (95% Cl : 1,128-27,398).Suggestion: To students to be pay more attention in their personal hygiene, propose to teachers to be able to regularly check the student hygiene such as nail hygiene and make a source of information media in the school environment. Finally, this study asked the health centers to conduct child health screening and conduct counseling about personal hygiene.
Effects of health training in knowledge and surgical wound management
Authors: Chrisanto Eka Yudha , Afni Nur
Published: December 2019

Background: The surgery in Indonesia ranks 11th out of 50 treatments for disease patterns in hospitals in Indonesia, which is an estimated 32% of them were laparotomy. The number of abdominal surgical cases in Lampung Province in 2017 was (28.95%) and increased in 2018 by (32.45%).Purpose: Know the effect of health training in knowledge and surgical wound management.Methods: This type of study was quantitative, with the Pre-Experiment design and the design one group pre test - post test. The populations were all of postoperative patients and samples of 34 people with a total sampling technique. Data collection uses questionnaire sheets and the statistical test used dependent t-test.Results: The average knowledge about postoperative wound care before being given health training of 14.18 and a standard deviation of 1.749. The average knowledge about postoperative wound care after being given health training of 17.06 and a standard deviation of 3.142, with p-value = (0,000 <0,05).Conclusion: There was the effect of health training in knowledge and surgical wound management. Health workers are expected to be able to apply the provision of health training to postoperative patients to improve patient knowledge in subsequent care and be used as a reference for making policies regarding the provision of health training to postoperative patients.
Spiritual counseling on anxiety level in (Lombok) Indonesian earthquake victims
Authors: Thoyibah Zurriyatun , Purqoti Dewi Nur Sukma , Oktaviana Elisa
Published: December 2019

Background: An earthquake has  an impact on mental health problems. Lombok earthquake victims undergo an anxiety, neurotic, psychotic symptoms, and Post Traumatic Syndrome Disease. Anxiety have an impact on the mind, body and it cause of physical illness. One of the nursing interventions that can be given to deal with anxiety includes spiritual counseling, which is given so that disaster victims accept their conditions, it is not making disaster a burden and reducing anxiety.Purpose: To determine the effect of Spiritual counseling on anxiety level  in (Lombok) Indonesian earthquake victims.Methods: Quantitative study with a pre-experimental approach using one group pre-post-test design on 25 earthquake victims in Lombok. The instrument was used the Hamilton Anxiety Rating Scale  questionnaire and the standard operational procedures for spiritual counseling. Data were analyzed using univariate analysis and t dependent test.Results: The anxiety score before spiritual counseling was 19.60 ± 3.26, while the anxiety score after spiritual counseling was 10.04 ± 4.13. Statistical tests showed a significant difference between anxiety levels before and after spiritual counseling for earthquake victims in Lombok (p <0.05).Conclusion: Earthquake victims in order to improve their spiritual quality by joining religious activities routinely to calm the mind and reduce anxiety or trauma, it is caused by earthquakes.
Salmonella-Infected Aortic Aneurysm: Investigating Pathogenesis Using Salmonella Serotypes
Authors: CHU CHISHIH , WONG MIN YI , CHIU CHENG-HSUN , TSENG YUAN-HSI , CHEN CHYI-LIANG , HUANG YAO-KUANG
Published: December 2019

Salmonella infection is most common in patients with infected aortic aneurysm, especially in Asia. When the aortic wall is heavily atherosclerotic, the intima is vulnerable to invasion by Salmonella, leading to the development of infected aortic aneurysm. By using THP-1 macrophage-derived foam cells to mimic atherosclerosis, we investigated the role of three Salmonella enterica serotypes – Typhimurium, Enteritidis, and Choleraesuis – in foam cell autophagy and inflammasome formation. Herein, we provide possible pathogenesis of Salmonella-associated infected aortic aneurysms. Three S. enterica serotypes with or without virulence plasmid were studied. Through Western blotting, we investigated cell autophagy induction and inflammasome formation in Salmonella-infected THP-1 macrophage-derived foam cells, detected CD36 expression after Salmonella infection through flow cytometry, and measured interleukin (IL)-1β, IL-12, and interferon (IFN)-α levels through enzyme-linked immunosorbent assay. At 0.5 h after infection, plasmid-bearing S. Enteritidis OU7130 induced the highest foam cell autophagy – significantly higher than that induced by plasmid-less OU7067. However, plasmid-bearing S. Choleraesuis induced less foam cell autophagy than did its plasmid-less strain. In foam cells, plasmid-less Salmonella infection (particularly S. Choleraesuis OU7266 infection) led to higher CD36 expression than did plasmid-bearing strains infection. OU7130 and OU7266 infection induced the highest IL-1β secretion. OU7067-infected foam cells secreted the highest IL-12p35 level. Plasmid-bearing S. Typhimurium OU5045 induced a higher IFN-α level than did other Salmonella serotypes. Salmonella serotypes are correlated with foam cell autophagy and IL-1β secretion. Salmonella may affect the course of foam cells formation, or even aortic aneurysm, through autophagy.
Improving The Interest of Back Through Tourist attraction, Accessibility and Promotion Dedicated by Tourism Satisfaction in Object Tourism Floating Markets in South Kalimantan Province
Authors: Akos Misransyah
Published: December 2019

The purpose of this study is: 1) To find out, test and analyze the influence of tourist Attraction on tourist satisfaction 2) To find out, test and analyze the influence of accessibility on tourist satisfaction, 3) To find out, test and analyze the effects of promotions on tourist satisfaction, and, 4) To find out, test and analyze the effect of tourist satisfaction on the interest in returning to a tourist visit. This research is an observation that is quantitative research by taking samples in tourist objects, with explanatory approach, that is explanatory research to test the influence between variables used in research. The population used in this research is tourists who visit in two tourist objects, namely Muara Kuin floating market and Lok Baintan floating market because the population is discrete, so the sampling used is as much as 150 tourists and the sampling technique using purposive sampling technique. The analysis technique used in this research is multiple linear regression analysis that is linear relationship between two or more independent variables with dependent variable. Based on the results of the research hypothesis proved that from 4 independent variables used in this study only one variable that is influential but not significant, namely the accessibility variable, this is because the object of this floating market is in the residential community so that the existing infrastructure is sufficient to go to the tourist location. Whether it is road and river road, while for variable attraction of tourist attraction, promotional activities have a significant effect on the satisfaction of tourists.
Product marketing strategy of Kapal Api Group uses SWOT Analysis
Authors: Septiani Fauziah , Astria Kenny
Published: December 2019

Fastrata buana corporation was founded in 1992 in Jakarta. The fastrata buana handles the sale and product distribution of the kapal api group to ensure delivery to customer. Fastrata buana is the largest distribution company in Indonesia With branch and distribution point in Sumatra, Java, Bali, kalimantan, sulawesi and even Papua.The research aims to see  what is a marketing strategy of the company's products. By doing SWOT analysis, counting the IFAS and EFAS get recapitulation S-W = a score of 1.5 and O-T =  a score of 1,25.It shows that the company's strategy lies within the quadrant 1.  Based on analysis of the internal strategy factors that can be seen in the diagram of the SWOT analysis, where the kopi kapal api position is in quadrant 1 that indicates the SO strategy in the SWOT matrix, which is aggressive strategy.An aggressive strategy is one that uses all the power to seize the opportunity.the strategy is one which gives benefit because having opportunity and power to be used improving Fastrata buana corporation.
The Impact of Discipline and Motivation Towards Employee Performance in The Permata Pamulang Hospital
Authors: Maduningtias Lucia
Published: December 2019

The purpose of this study is to figure out the impact of motivation and discipline toward the employee performance in The Permata Pamulang Hospital both partially and simultaneously. This study used saturated samples, so all of 55 hospital employees in The Permata Pamulang Hospital be respondents from this study. The data-collecting tool that was used is a questionnaire, and the data used is primary data. Data collected was analyzed by multiple linear regression analysis with hypothetical test, with partial test (t) and simultaneous test (F). The analysis results of the disciplinary and motivational impact towards employee performance in Permata Pamulang Hospital with simple correlation number = 0,857, it means that discipline and motivation have a moderate level of relation towards employee performance. In equations of multiple linear regressions, it was obtained Y = 4,097 + 0.48 X1 + 0.53 X2, which means that when X variable is increased to 1 unit, thus Y variable will increase to 0.48 + 0.53 units at 4,907 constant. Determination coefficient values of 72% show that the amount of disciplinary and motivational variables in the effort to increase the employee performance, the other 28% were affected by other unstudied variables in this study. After significant testing by using the "t test", it was obtained that t-count > t-table where 4,320 > 2,007 which means Ho was rejected and Ha is accepted, this means there is a significant influence between discipline and motivation toward employee performance in The Permata Pamulang Hospital.
The Influence of Entrepreneurship Subject on Students Entrepreneurial Intention
Authors: Fitriasari Fika
Published: December 2019

Industrial Era 4.0 exposes people to global uncertainty. This condition requires an integrated and comprehensive response to anticipate the emergence of new problems, one of which is the increasing number of unemployment in Indonesia. Recordings of the Central Bureau of Statistics in August 2018 stated that the open unemployment rate was still dominated by vocational high school graduates. One effort to deal with this condition is by equipping students with entrepreneurial competencies. Hopefully after graduation, students are able to have an independent business. This study was conducted to measure the success of learning entrepreneurship subjects and their role in growing students’ intentions in entrepreneurship. This research was conducted at SMK (Vocational Senior High School) 17 YP Selorejo using a quantitative approach with correlational type. The research respondents were students majoring in Commerce, using a full sample of 50 students. The data analysis uses product moment and multiple linear regression analysis. After the data analysis process was carried out, it can be concluded that both partially and simultaneously, entrepreneurship subjects are divided into two variables, namely the students' understanding of material (material understanding) variables and the teaching methods chosen by the teacher significantly influence students’ entrepreneurial intentions.
The Usage of Social Media As A Trial of Political Attitudes in Indonesia
Authors: Lekik Oktavianus Klau
Published: December 2019

Nowdays, social media has the potential to become a wave of information and opinion. Mass mobilization is now easier with social media, and of course the cost is very affordable and free. In addition, exposure to social media is very fast taking reactions from the public. If it is not done well, the legitimacy and reputation of a political figure can decline rapidly. Social media is able to provide the public with information both about politics and the capacity and credibility of the attitudes of political leaders, with the breadth of networks owned by social media, people can learn about politics from social media. In fact, social media facilitates the public to know the statements of the attitudes of political leaders regarding a particular discussion and can make the community become political literate. Thus, in general, social media is a trend that can be useful as a media for political campaigning, expressing cheap and effective political attitudes and political learning. This study, the authors focus on analyzing the Use of Social Media as a Form of Political Attitude in Indonesia, with the aim to be achieved by the author to find out, Firstly, this study is to understand the cultural context of political actors in using social media as a form of political attitudes to influence the final community recently on social media. Secondly, the desire to describe the ways political actors use social media to express their political attitudes and express themselves through social media to influence everyday people's behavior. Thirdly, in the form of political attitudes using cultural symbols both based on religion, ethnicity, streams or certain groups that have interests expressed by various political actors and other groups to provoke the public through social media. Using the review literature method is descriptive analytical. Analytical descriptive research can be used to analyze data and facts that occur about the use of social media as a form of political attitudes. The results and conclusions of this study that, the use of social media to express political attitudes by political leaders, both in speeches, influencing and provoking the public are very easily spread through social media. This must be responded to well by social media users to use reasoning to think positively in expressing their political attitudes through social media, by using an understanding of media literacy, information literacy and technology literacy which is basically a source of truth.
A Survey on Efficient Parallelization of Blockchain-based Smart Contracts
Authors: Meneghetti Alessio , Parise Tommaso , Sala Massimiliano , Taufer Daniele
Published: December 2019

The main problem faced by smart contract platforms is the amount of time and computational power required to reach consensus. In a classical blockchain model, each operation is in fact performed by each node, both to update the status and to validate the results of the calculations performed by others. In this short survey we sketch some state-of-the-art approaches to obtain an efficient and scalable computation of smart contracts. Particular emphasis is given to sharding, a promising method that allows parallelization and therefore a more efficient management of the computational resources of the network.
Estimation of genetic diversity in the germplasm of Brassica Campestris (L.) Using morphological and biochemical markers
Authors: ULLAH ZAKIR
Published: December 2019

A total of 60 genotypes of Brassica campestris (L) germplasm were acquired from National Research Centre (NARC) Islamabad, Pakistan for the evaluation of genetic diversity using the morphological characters and SDS-PAGE analysis. These genotypes were grown-up in Plant Garden Department of plant sciences, University of Malakand, Khyber Pukhtunkhwa, Pakistan. For the assessment of genetic diversity total of 18 morphological traits were scored and their phylogenetic relationship were plot through cluster diagram. For the estimation of genetic diversity, we used the most influential technique SDS PAGE. We observed six loci (bands) from the collected genotypes; locus-1 (band-1) contained 100% bands of protein and obvious as monomorphic locus while loci i.e. 2,3,4,5 and 6 showed 28%, 42%, 36%, 56% and 25%, respectively variation and were polymorphic. The inter species locus influence toward genetic assortment (LCTGA) was 83.33% in the attained genotypes. Profiling through SDS PAGE based on two-way cluster plottingresolved effectively the collected genotype into 4 cluster. We consider that this work provides a baseline for the understanding genetic diversity in the common crops used in Pakistan and warrants further investigation in this newly evolving field of study.
Weed Flora in Cereal crops of district Bannu
Authors: ULLAH KHAN REHMAN
Published: December 2019

In the present research work (2016-2018), there was reported 100 genera having 114 species distributed among 37 families. Out of which 5 were of monoct families (with 21 genera and 23 spp.) and 32 families of dicot (with 79 genera & 91 spp.). According to percentage data, it was reported that the weed members of family Poaceae was the greatest in cereal crops having 16.666% spp, while the family Asteraceae was next one with 14.912% weeds spp. Family Boraginaceae and Papilionaceae gaining third position having 6.140% weeds spp. Amaranthaceae, Brassicaceae and Solanaceae having 5.263%, Euphorbiaceae (4.385%), Polygonaceae (3.508%), Zygophyllaceae (2.631%), while the remaining families have less then 2.00 % weeds species. It was reported that Cirsium arvense, Convolvulus arvensis, Conyza bonariensis, Cynodon dactylon, Cyperus rotundus, Parthenium hysterophorus andSonchus asper were the common weed found in all the three important cereal crops i.e wheat, maize and rice.
Study of Blood Glucose and SGPT lowering effect of Eucalyptus Lanceolata Linn. in Induced Diabetic Rabbits
Authors: YAOA MINGYUE
Published: December 2019

The part of the plant to curing the diabetes mellitus and improves available data on plants with hypoglycemic effects. Antidiuretic potential of eucalyptus extracts has been evaluated in alloxan-induced diabetic rabbit. Here we used, plants extract about 256 kg were mix with 1000 ml methanol and keep in Flask. After filtering the extracts were exposed to rotary evaporator machine that methanol separated from plant extract. In the Nine rabbit were divided into three different groups. The body weight was recorded on every 6 days interval. The data obtained revealed that eucalyptus extracts reduced the glucose level effectively. Such treatment with extracts decreased the SGPT level. Therefore, it is concluded that the eucalyptus possesses significant antidiabetic activity. And finally, we recommend this plant for medicinal uses and for pharmaceutical industries to isolate pure drugs.
Ameliorative potential of Anacyclus pyrethrum extract in generalized seizures in rat: Possible cholinergic mediated mechanism
Authors: Bezza Kenza , Gabbas Zineb El , Laadraoui Jawad , Laaradia Mehdi Ait , Oufquir Sara , Chait Abderrahman
Published: December 2019

The present study evaluates the anticonvulsant activity of the roots of Anacyclus pyrethrum using pilocarpine-induced experimental model of epilepsy in rat, and to determine its possible anticonvulsant mechanism. Ethanol extract (200 and 400 mg/kg) or alkylamides (25 and 50 mg/kg) was administered orally 45 min before the injection of pilocarpine-induced (400 mg/kg) seizures. The possible anticonvulsant mechanism was investigated by testing the effect of atropine (2 mL/kg) and scopolamine (1 mg/kg). The scoring of seizure severity, seizures time latency, duration of total seizures and percentage of mortality protection were recorded. Ethanol extract and alkylamides prolonged the time of onset seizure and decreased the duration of seizures compared to control group (p<0.001). The seizure protection was 100%. The co-administered of ethanol extract of A. pyrethrum and alkylamides with atropine completely abolished the pilocarpine-induced seizures.

Video Clip of Methodology:

Anticonvulsant effect: 6 min 7 sec:  Full Screen   Alternate
Antidepressant activity of Citrus limetta leaves in mice using battery of behavior models modulating via serotonergic systems
Authors: Kaur Jaspreet , Bhatia Manisha , Nain Parminder
Published: December 2019

The methanolic extract of Citrus limetta leaves was estimated in the present study for antidepressant activity. This activity was evaluated by using the rat behavioral model i.e. forced swimming and tail suspension model for 14 days, with estimation of neurotransmitters in animals brain. The sedative effect was evaluated by actophotometer. The extract (200 mg/kg) administered orally showed significant (p<0.05) decrease in immobility time against the standard drug fluoxetine (20 mg/kg, i.p), and imipramine (15 mg/kg, i.p.) respectively but no significant reduction was found in the locomotor activity against diazepam (2 mg/kg, i.p.). In depression, the brain reflected low monoamines level like release of norepinephrine, dopamine and serotonin but 14 days after successive administration of the extract, their levels were significantly increased. In conclusion, C. limetta showed significant antidepressant activity.  

Video Clip of Methodology:

Forced swimming test: 6 min 17 sec:  Full Screen   Alternate