bluuebunny/crossref_metadata_2025 huggingface dataset:
Applications of nanomedicine-integrated phototherapeutic agents in cancer theranostics: A comprehensive review of the current state of research
Authors: Shoaib Ambreen , Javed Shamama , Tabish Mohammad , Khan Mohammad Ehtisham , Zaki Mehvash , Alqahtani Saad S. , Sultan Muhammad H. , Ahsan Waquar , Afzal Mohd
Published: May 2024

Innovative approaches such as photodynamic therapy (PDT) and photothermal therapy (PTT) have made nanomedicines a promising frontier in cancer theranostics. The combination of nanocarriers with photothermal agents and photosensitizers (PSs) has shown excellent promise for the diagnosis and the treatment of cancer, primarily at the cellular, vascular, and tumor microenvironment level. Using nanocarriers in PDT has revolutionized precision and efficacy, allowing the drug to reach cancer cells faster and offering high enhancing PS accumulation. These agents are activated by light of specific wavelengths, leading to localized cytotoxicity, offering highly selective cancer therapy. Nanomaterials such as gold and silver nanoparticles have enabled remarkable progress in cancer hyperthermia using PTT. The unique optical properties of these nanoparticle-based nanomedicines make them ideal candidates for converting light energy into heat, selectively ablating the cancer cells. In this review, nanomedicine-integrated phototherapeutic agents are discussed and the most important recent developments in PDT and PTT are examined, as well as how nanoparticle-based formulations improve diagnosis and treatment. In addition, nanocarriers used in cancer phototherapy and their mode of action are discussed. Nanocarriers are useful for drug delivery as well as for imaging and diagnostic purposes during cancer treatment. In this review, we explore the role of nanoparticles in improving phototherapy precision and selectivity while minimizing collateral tissue damage. It specifies a comprehensive impression of the current research on cancer therapy, underscoring its potential to revolutionize the treatment paradigm by highlighting the current state of research.
Single-cell RNA-binding protein pattern-mediated molecular subtypes depict the hallmarks of the tumor microenvironment in bladder urothelial carcinoma
Authors: Zhang Jun , He Jiejie , Chen Wen , Chen Guojun , Wang Liang , Liu Yuchan , Wang Zhanjin , Yang Ming , Huang Guoyi , Yang Yongli , Ma Wei , Li Yan
Published: May 2024

Objectives

Bladder carcinoma (BC) is a common malignancy of the urinary tract. As a new hallmark of cancer for drug therapy, RNA-binding proteins (RBPs) are key regulatory factors in alternative splicing events. This work is to uncover the relationship between BC and RBP in order to find drug targets in BC.

Methods

In this work, data from single-cell RNA-seq GSE1355337, PRJNA662018, and the TCGA-Bladder urothelial carcinoma (BLCA) cohorts are integrated to identify their relationships. A scoring system is constructed according to RBPs gene expression and patients’ survival. A network is constructed to analyze the alternative splicing events and RBP genes.

Results

A scoring system identified 321 RBPs significantly associated with the prognosis of patients. Subsequent typing of these RBP genes in two single-cell datasets demonstrated that most of the RBP genes had variable copy numbers. Three RBP clusters were identified. Using RBP genes as a signature in BC epithelial cells allows for differentiation between different grades of BC samples. The novel RBP genes-based subtype system reflects BC clinical staging. Notably, CellChat analysis revealed that the RBP genes-associated cell subtypes of T cells had extensive interactions with epithelial cells. Further analysis showed that the ligand-receptor pair MIF-CXCR4 mediated the communication between RBP-associated subtypes of BC epithelial cells and T cells.

Conclusions

Taken together, RBP genes are associated with BC progress and offer new indicators for precision medicine in BC.
Eine Titeldivergenz in den Grabräuberpapyri
Authors: Böhm Billy
Published: May 2024

In papyrus Amherst 6 + Léopold II (16th regnal year of Ramesses IX) of the so-called Tomb Robbery Papyri, a certain Amenemheb is mentioned three times among a number of other individuals. He was convicted of robbing the tombs of western Thebes. In this context, the titles attributed to him on the papyrus are of particular interest. In 2:2 and 3:13, he is referred to as “cultivator of the temple of Amenope” (ꜥḥ.wtj n(.j) pr Jmn-jp.t), whereas, in 4:6 he is called “agent of the temple of Amenope” (rwḏ.w Jmn-m-ḥb n(.j) pr Jmn-jp.t). Based on a detailed analysis of the contents of Papyrus Amherst 6 + Léopold II, this article demonstrates that the reason for this difference is ouster. This means that Amenemheb at least formally lost his office – unlike his colleagues. Afterwards, he was sentenced to death, which is not mentioned explicitly in the text but which we may assume with some certainty. If this is correct, this is one of the few examples of ouster as a punishment being carried out in reality. However, it was not targeted primarily at the denial of the delinquent’s access to the assets, which were tied to it.
Learning Through Practice: On How Kemyt Contributed to Crafting and Transmitting Scribal Knowledge
Authors: Motte Aurore
Published: May 2024

This paper is conceived as a first step towards the Kemyt (re)contextualization. By exploring the specific layout and paratext of Kemyt, it intends to shed light on the scribes who wrote the many partial copies of this letter-like composition and in which circumstances. I first address the layout, the ink choices, and the writing orientation. I then turn my attention to the text structure: dividers, ending marks, as well as colophons, dedications, and underwriting. The dated ostraca and their frequent identification as school exercises are discussed before moving on to the textual revision practices and looking for an explanation to the low proportion of corrected texts despite faulty content. All this enabled me to highlight a set of scribal practices, in which scribes draw, some being proper to the Kemyt, some being common to the rest of the text production. These practices revealed a complex network, from beginning students to senior scribes, through assistant scribes and early career scribes, which contributed to the crafting and the transmission of scribal knowledge during the New Kingdom.
Hor-resnet ou Hor-nesout? Étude onomastique et prosopographique
Authors: Claude Marion
Published: May 2024

The anthroponymy of the people of Akhmim is often quite specific. Among the local anthroponyms is one formed with the name of Horus followed by an epithet of uncertain reading. This short note aims at reviewing the evidence in order to decide between the standard reading, Ḥr-Rsn.t and a more recent, but as yet unproven, interpretation, Ḥr-nswt. A list of individuals bearing this name is also attached.
Papyrus PM 49.11.1, Dating the Great Tomb Robberies, and the Chronology of the Late 20th Dynasty
Authors: Antoine Jean-Christophe
Published: May 2024

The Great Tomb Robbery papyri are a major source of information on the end of the 20th Dynasty. Questioned in year 1 of the Renaissance thieves mention the taking of Medinet Habu by foreign troops, an attack of Hardai in Middle Egypt by the Viceroy of Kush Panehsi, and a temporary destitution of the High Priest of Amun (HPA), that are unfortunately not dated. The way forward to resolve this uncertainty is to date the thefts themselves since they were contemporaneous. For this we systematically reviewed what we know of the prosopography of the people involved in the thefts and their investigation. The result shows that tombs and temples robberies mostly occurred between the end of the reign of Ramesses IX and the early years of Ramesses XI. In addition, P. PM 49.11.1 mentions an otherwise unattested HPA Nesmut. The consequences of these results on the history of this period are discussed.
Zwei koptische grammatische Morpheme bislang ungeklärten Ursprungs
Authors: Peust Carsten
Published: May 2024

This paper discusses two Coptic morphemes whose etymology has remained obscure to this day, namely the n-prefix of the so-called adjective verbs such as ⲛ-ⲁⲛⲟⲩ= „is good“, as well as the particle ⲡⲉ that often accompanies the preterite converter. It is suggested that both of them came into existence by a false segmentation of contexts in which their predecessors typically used to occur.
MODELOS DE LINGUAGEM AVANÇADOS, BANCOS DE DADOS VETORIAIS E O NOVO PARADIGMA PARA ANALYTICS
Authors: Junior Manoel Villas Bôas , Da Silva Antônio José Dias , Gonçalves Luis Felipe Vieira
Published: May 2024

Este artigo explora o papel transformador dos Modelos de Linguagem Avançados (LLM’s) no campo da análise de dados e na tomada de decisões empresariais. Com o foco nos LLM’s, como o GPT-4 da OpenAI, é apresentado suas capacidades e aplicações, destacando a capacidade de processamento de linguagem natural (PLN) que permite a compreensão e geração de texto semelhante ao humano. Essa habilidade de processar dados não estruturados, como avaliações de clientes, posts em mídias sociais e artigos de notícias, possibilita extrair informações valiosas, identificar padrões e obter insights antes inacessíveis. Além disso, é explorado como os LLM’s estão impulsionando a adoção de bancos de dados vetoriais, um novo tipo de banco de dados NoSQL (non-structured query language) projetado para lidar com dados complexos e de alta dimensão, representados em vetores, contribuindo para a melhoria na análise de dados e na tomada de decisões baseada em dados. Como proposta será demonstrado de maneira prática como configurar e utilizar um LLM consultando uma base de dados vetorial, e apontado quão práticos, confiáveis, performáticos e eficientes são os resultados gerados.
Recollecting The Unforgettable: Interrogating Migration, Trauma and Identity In Select Tripura Bengali Poems
Authors: Chakraborty Jagriti , Chakrabarty Madhumita
Published: May 2024

The human mind retains the sequences of episodes that include prior experiences, memories and narratives. The traumatic memories of past are the one which stays in the subconscious and the recollection of those events formulates images of terror. Partition of India is one such event which incorporates narratives of multiple experiences of migration and separation. Tripura a small hilly state of North East India has seen the flood of migrants even before the major India Pakistan division took place. Most of Bengalis settled in Tripura have their roots in East Pakistan or which is after 1971 known as Bangladesh. Many decades have passed but they are still carrying their stories of migration and passing it to generation after generation. The trauma of separation from homeland becomes part of their memory and gets registered by the help of literature.  This paper aims to examine select poems of Tripura which focuses upon the relation of migration and memory.
Role of Deep Learning in Diagnosis, Treatment, and Prognosis of Oncological Conditions
Authors: Umar Muhammad , Shiwlani Ashish , Saeed Fiza , Ahmad Ahsan , Shah Masoomi Hifazat Ali , Tahir Anoosha
Published: May 2024

Deep learning, a branch of artificial intelligence, excavates massive data sets for patterns and predictions using a machine learning method known as artificial neural networks. Research on the potential applications of deep learning in understanding the intricate biology of cancer has intensified due to its increasing applications among healthcare domains and the accessibility of extensively characterized cancer datasets. Although preliminary findings are encouraging, this is a fast-moving sector where novel insights into deep learning and cancer biology are being discovered. We give a framework for new deep learning methods and their applications in oncology in this review. Our attention was directed towards its applications for DNA methylation, transcriptomic, and genomic data, along with histopathological inferences. We offer insights into how these disparate data sets can be combined for the creation of decision support systems. Specific instances of learning applications in cancer prognosis, diagnosis, and therapy planning are presented. Additionally, the present barriers and difficulties in deep learning applications in the field of precision oncology, such as the dearth of phenotypical data and the requirement for more explicable deep learning techniques have been elaborated. We wrap up by talking about ways to get beyond the existing challenges so that deep learning can be used in healthcare settings in the future.
Formulation Design and Development of Fast Disintegrating Tablets of Losartan Potassium By Using Locast Bean Gum As Superdisintigrants
Authors: Singh Kehar , Dadabhau Gaikwad Dushyant , Singh Satbir
Published: May 2024

For patients who have trouble swallowing tablets, capsules, etc., fast dissolving drug delivery devices provide an option. Water is not necessary for the swallowing of fast dissolving pills because they dissolve instantly in the mouth. Using locust bean gum as a natural superdisintegrant, the present work set out to produce fast-dissolving tablets of losartan potassium. Perform pre formulation studies like partition coefficient, solubility and identification of drug. The influence of precompressional parameters like interaction studies and compatibility. Other tablet properties were examined, as well as the impact of formulation parameters on losartan potassium disintegration and in-vitro dissolution. The findings indicated that the 7.5% concentration of locust bean gum had good superdisintegrant qualities and produced quickly dissolving tablets. The best tablet formulation (F3) had a 20-second minimum disintegration time and a 30-minute maximum drug release of 98%. The locust bean gum was discovered to have a notable ability to be employed as a superdisintegrant, with a swelling index of 22. The DSC analysis and IR spectra demonstrated that there was no interaction of any type with the tablet's formulation ingredients. Accelerated short-term experiments on optimized formulation show no appreciable modifications to the formulation.
Evaluation of Blood Culture Results in Patients with Malignancy in Erzurum Province, Turkey
Authors: Aktas Osman , Akbaba Ozgür , Uyanik Muhammet Hamidullah , Uslu Hakan
Published: May 2024

Background: Bloodstream infections are a serious public health problem that requires follow-up with blood culture; this negatively affects the course of the disease and patient healthcare costs in patients with malignancy. This study aimed to determine the growth frequency of pathogens and their antibiotic resistance profiles in the blood cultures of patients with hematological and oncogenic malignancies.Materials and methods: The results of 7451 blood cultures, obtained from 2926 patients between January 2017 and January 2022, were evaluated retrospectively. Of these cultures, 3969 were obtained from patients with malignancy (diagnostic codes C00-D48 in ICD-10) and 3482 from patients without malignancy. The hospital information management system modules were used to acquire patient data and blood culture results.Results: Various microorganisms grew in 10.1% of blood cultures. Of these organisms, 64.1% were isolated from cases of malignancy. Of the pathogens, 49.2% were gram-negative bacteria, 47.7% were gram-positive bacteria, and 3.1% were fungi. The most frequently isolated bacteria were methicillin-resistant coagulase-negative staphylococci (3.2%), Escherichia coli (2.3%), Klebsiella pneumoniae (1.0%), methicillin-sensitive coagulase-negative staphylococci (0.7%), and Staphylococcus aureus (0.6%). Pathogen positivity was highest in the patient cultures with urinary system cancer (23.9%), thyroid and other endocrine gland cancers (20.6%), female and male genital organ cancers (18.2%/16.9%), and digestive organ cancer (14.2%). Gram-negative bacteria to ampicillin, piperacillin, and sulfamethoxazole-trimethoprim and Gram-positive bacteria to penicillin, erythromycin, and sulfamethoxazole-trimethoprim were highly resistant. Combined resistance to imipenem and meropenem was observed in 25 Gram-negative bacteria. Twelve (48%) of the carbapenem-resistant bacteria were isolated from patients with lymphoid, hematopoietic, and related tissue malignant neoplasia.Conclusion: This study reported microorganisms and their antimicrobial resistance in the blood cultures of malignant patients, a special patient group. It pointed out that the antibiotic resistance of Staphylococcus, Klebsiella pneumoniae, and E. coli is high enough to cause problems in the treatment of patients with malignancy.
Accidental Intravenous Administration of Simethicone in a 4-Year-Old Patient: A Case Report
Authors: Lozovskytė Agnė , Laubner Sakalauskienė Gabija , Badaras Robertas
Published: May 2024

Simethicone is an antiflatulent medication exclusively administered orally, thus its systemic effects remain unknown. We present a case of an inadvertent intravenous administration of simethicone to a 4-year-old patient, precipitating respiratory difficulty, cyanosis, and altered mental status. The patient’s condition improved rapidly with appropriate interventions, leading to discharge in a fully recovered state. To date, only one documented instance of intravenous simethicone administration exists in medical literature.
Project Spotlight: Concrete flower bed springs from park along the Hudson
Authors: Atkinson William
Published: May 2024

Little Island at Pier 55 uses precast concrete tulips manufactured by the Fort Miller Co. Inc. to create a new whimsical park in New York, N.Y. Because of their large size, the precast concrete pots were delivered by barge.
Manajemen Pondok Pesantren Sabiilul Huda dalam Pembentukan Kemandirian Santri di Kota Bandung
Authors: Putra Agung Sembhara , Muhyiddin Asep
Published: May 2024

Islamic boarding schools are tertian educational institutions in Indonesia whose existence as centers of Islamic education have a very large role in shaping the character of the Indonesian nation. This paper aims to determine the application of management functions and elements to the Sabiilul Huda Islamic Boarding School as an effort to establish the independence of students with management. The method used in this research is descriptive method, because the main objective of this research is to find out and provide an explanation of the formation of the independence of the students based on management by applying the functions and elements of management to the students. The results of this study show that management in the formation of student independence is implemented by the Sabiilul Huda Islamic Boarding School. Based on these findings it can be concluded that the management of the Sabiilul Huda Islamic Boarding School is in the establishment of independence in order to improve the management function of the Sabiilul Huda Islamic Boarding School. The application of management functions and elements to Islamic boarding schools is an application of science to the reality of the process of achieving goals in the process of self-reliance of students, one of which is carried out at the Sabiilul Huda Islamic Boarding School.
Penerapan Fungsi Manajemen Lembaga Cerdas Al-Quran di Bandung Barat
Authors: Virgions Nicolous , Sanusi Irfan , Yuliani Yuliani
Published: May 2024

Management is an activity that includes planning, organizing, implementing and controlling. So a good management in the management of the institution is very important because in the development process of an institution can be seen from planning, organizing, implementing and supervising it. The Al-Quran Smart Institute is a da'wah institution that is engaged in reading the Al-Quran. The purpose of this research is to find out the planning, organizing, implementation, and supervision in implementing the management functions of the Al-Quran Smart Institute. The theory used in this research is management theory by George Terry. The results of this study show that the Al-Quran Research Institute (LCA) in West Bandung Regency always does its best to improve the quality of the people. The planning carried out by the Al-Quran Smart Institute to improve the quality of the ummah is well done, structured and systematic. Organizing consists of division of labor, grouping and division of tasks and authority. So that with limited human resources can be maximized. Implementation is done by realizing the program that has been planned. Supervision using direct supervision method. Aims to know the condition of the field.
Manajemen Strategi Pendidikan Pondok Pesantren Al-Hasan Banjarsari Ciamis dalam Membina Kedisiplinan Santri di Masa Pandemi Covid-19
Authors: Sa'diah Dewi , Hamdani Amin , Mubarok Ridwan
Published: May 2024

In the current era, the presence of Islamic boarding schools is very urgent to support the progress of the Indonesian nation. Because the Islamic boarding school system teaches not only religious matters (tafaquh fid din) but also the basics of science and technology, social and cultural boarding schools, al-Karima morals, independence, simplicity, modesty, honesty, togetherness, compassion, discipline, this research aims to determine the formulation and implementation of Islamic boarding school education carried out by kiai at Islamic boarding schools in fostering santri discipline during the Covid-19 pandemic and to evaluate changes in santri behavior in fostering santri discipline at Islamic boarding schools. This research uses a descriptive method with a qualitative approach. The results of this research show that the formulations carried out by kiai in Islamic boarding schools in fostering student discipline during the COVID-19 period include a. Formulate the vision, mission, goals, and educational programs of the Islamic boarding school as expected; b. Create disciplinary regulations and guidelines for violations and punishments, and determine a schedule for student disciplinary activities. The implementation of Islamic boarding school education carried out by kiai includes a. providing direction, role models, advice, good example, motivation, enthusiasm, leading throughout students' disciplinary education, and communicating well. Evaluation of changes in student behavior in fostering student discipline includes: Changes in students' behavior occur because they have habits that have been ingrained in them with their awareness and are always guided by their kiai, mentors, ustadz, and ustadzah.
Pengaruh Gaya Kepemimpinan terhadap Produktivitas Kerja Pegawai BAZNAS Kabupaten Sukabumi
Authors: Alfiana Muhammad Marse , Rustandi Ridwan , Sanusi Irfan
Published: May 2024

In this competitive globalization era, improving work quality and employee productivity is an important challenge for organizations in various sectors. Leadership style is known to be a key factor influencing this productivity. The main objective of this study is to investigate how much and what influence leadership style has on the work productivity of BAZNAS Sukabumi district employees. This research method uses a survey with a questionnaire as a data collection tool from 27 Sukabumi Regency BAZNAS employees. The research findings confirm the positive and significant influence of the leadership style possessed by the leader on employee work productivity. The results show that the leadership style variable is able to explain 28% of the variation in employee work productivity, emphasizing the important role of leadership style in increasing organizational efficiency and performance. This study also details that a leadership style that is smart, understands people, and has good management skills has a significant positive impact on employee self-development, morale, and improvement of work quality and efficiency.
Manajemen Dakwah Takmir Masjid Jogokaryan dalam Membangun Peradaban Islam di Mantrijeron Yogyakarta
Authors: Arsam Arsam , Nurmahyati Siti , Amaluddin Asep
Published: May 2024

This paper describes the management of the preaching of the takmir of the Jogokaryan mosque in building Islamic civilization. The background is about the empirical condition of the mosque which is not functioning according to expectations as was the time of the prophet Muhammad SAW and his companions. The mosque is only used as a place for ritual worship activities, even having the impression that the mosque is only a symbol of the existence of Muslims in an area and not a solution for the people. The purpose of this study was to determine the management of preaching takmir at the Jogokaryan mosque in building Islamic civilization in Jogokaryan Mantrijeron, Yogyakarta. The research method used is descriptive qualitative method. While the data analysis used in this study is the method of analysis of Mile and Huberman. The results of the study concluded that the management of the Jogokaryan Mosque can be categorized as having a level of success in building Islamic civilization, namely by carrying out da'wah management functions, namely: 1) Da'wah planning which includes da'wah mapping, service, empowerment and coaching. 2) Organizing da'wah activities. 3) implementation by moving the person in charge of the activity. 4) Supervision of da'wah, namely monitoring or monitoring da'wah activities. The Da'wah management activities are carried out continuously and continuously.
Rocket Spanish
Authors: Shin Daeun
Published: May 2024

Rocket Spanish is a part of Rocket Languages, which produces online and app-based language learning courseware and was founded in 2004. The courseware claims to help users develop their spoken target language skills by providing real-world conversations as models.
Inadequate Aural Vocabulary Knowledge of High-Frequency Words
Authors: Matthews Joshua , Lange Kriss
Published: May 2024

Aural vocabulary knowledge (AVK) of high-frequency words is critical for second language listening comprehension. However, learners of English as a foreign language (EFL), despite considerable periods of language study, often do not have the AVK needed for basic communicative competence. A mixed methods approach is applied to determine whether mobile-assisted language learning (MALL) can help solve this problem. First, a cohort of 33 Japanese EFL students with suboptimal AVK were divided into a treatment group (n = 17) and a control group (n = 16). Over a two-month period, the treatment group used a MALL application that enabled self-assessment and teacher monitoring of learners’ AVK of 1,000 frequently occurring English words. A comparison of pre- and post-test scores between the treatment and control group suggested that the MALL intervention was associated with improvements in AVK. Further, data stored by the application enabled an analysis of the words learners found most difficult, and interviews with a sub-group (n = 5) were undertaken. Results suggested that reduced forms and the influence of Japanese phonotactics were key factors limiting the ability to recognize spoken words. Links to resources that can help learners improve AVK of high-frequency words are provided and pedagogical implications are discussed.
Variability in English-Spanish bilingual phonotactics
Authors: Tetzloff Katerina
Published: May 2024

Spanish prohibits initial sC clusters. Past studies have reported that this phonotactic restriction results in the perception of an illusory /e/, ‘repairing’ the illicit sequence (e.g., spid perceived as espid). Because English allows sC clusters, English-Spanish bilinguals are confronted with conflicting phonotactic systems. The present study investigated if this locus of phonotactic conflict yields bilingual variability (i.e., non-monolingual-like language behavior). Spanish monolinguals and English-Spanish bilinguals performed a nonce word judgment task, whereby they assigned acceptability ratings to sC-initial nonce words. Monolinguals were highly unaccepting of sC-initial words, whereas bilinguals were more likely to accept them as phonotactically licit, showing evidence of bilingual variability. The bilingual variability was constrained by English phonotactics, as sC clusters were rated as significantly more acceptable than other illicit onset clusters that are illicit in both languages. Furthermore, the monolinguals failed to show evidence of an illusory vowel effect, highlighting the importance of task type in phonotactic perception studies.
Words can only get us so far
Authors: Pulido Manuel F.
Published: May 2024

The traditional ontological division between the lexicon and grammar has often resulted in a reductionist view of the lexicon and lexical competence as composed of individual words in isolation. This narrow view of the lexicon has transcended disciplinary boundaries and is apparent in the focus on single words of widely used psycholinguistic measures of language (e.g. picture naming, verbal fluency, lexical decision) and cognitive ability alike (e.g. Stroop, recall in working memory span). This article argues that such an approach has imposed limitations on the questions that can be examined by researchers and on the generalizability of some results. Here I propose that, rather than assigning multiword units their own ‘niche’ in psycholinguistic studies, they should be viewed as part of the way core lexical competence is measured and conceptualized, both in monolingual and bilingual speakers. I also review promising advances in recent years brought about by a surge in the number of studies focused on multiword units and by new tasks of individual cognitive skill (e.g. multiword-based chunking ability). These hold the potential to allow for a cross-disciplinary shift in the examination of lexical competence as grounded in community-based norms and in line with current usage-based approaches.
Obraz mężczyzny i kobiety w katolickich epitafiach kresowych z XIX i początku XX wieku (na przykładzie Podola)
Authors: Havryliuk Olena
Published: May 2024

Artykuł jest pokłosiem badań inskrypcji nagrobnych z XIX – początku XX wieku na katolickich cmentarzach Podola. We wstępie przedstawiono krótką historię Podola, a także życia Polaków na ziemi podolskiej. Analizie poddano części fakultatywne inskrypcji, w których utrwalano nacechowaną aksjologicznie charakterystykę zmarłych kobiet i mężczyzn: pochodzenie, zajmowane stanowisko, relacje rodzinne i społeczne. Wyniki analiz pokazują zbiorowy obraz Polaków zapisany w inskrypcjach na podolskich cmentarzach – to, jakie cechy i zachowania były cenione we wspólnocie polskiej Podola. Porównanie zaznaczonych cech zmarłych męskiej i żeńskiej płci świadczy też o roli kobiet i mężczyzn pochodzenia polskiego na Podolu, o różnicy ich statusu w społeczeństwie, co dokumentują charakterystyki w wybranych inskrypcjach nagrobnych.
Obraz polskości i Polaków na chicagowskiej scenie polonijnej początków XX wieku (wokół twórczości dramaturgicznej Antoniego Jaxa) – zarys problematyki
Authors: Reglińska-Jemioł Anna
Published: May 2024

Polacy docierający do Stanów Zjednoczonych sukcesywnie reorganizowali zastaną przestrzeń, budując świątynie, tworząc placówki edukacyjne, zakładając różnego rodzaju instytucje, a także teatry – by również za ich pośrednictwem oddziaływać dydaktycznie. Jak podkreśla Emil Orzechowski w monografii poświęconej Teatrowi polonijnemu w Stanach Zjednoczonych (Wrocław 1989, s. 34), „nader intensywnie eksploatowano wątek patriotyczny, co również wypada uznać nie za zabieg mający na celu zwabienie publiczności, lecz raczej za świadomie wprowadzony element wychowania w duchu pamięci o historii polskiej”. Interesująca właśnie z tej perspektywy wydaje się twórczość Antoniego Jaxa (1850–1926), w pewnym sensie zapomnianego dramaturga chicagowskiej sceny amatorskiej, na której potrzeby napisał kilkadziesiąt sztuk. Dzięki jego twórczości możemy spojrzeć na dziedzictwo kulturowe zapisane na kartach polonijnego teatru amatorskiego nie tylko z perspektywy emocjonalnych zapisów starań Polonii o identyfikację z kulturą kraju rodzinnego, czy też refleksyjnego oglądu własnej przeszłości. Jax w swych komediach, zbliżając się do formy farsy, chętnie odnosił się przede wszystkim do aktualnych tematów, spraw bliskich codzienności i doświadczeniom polskich imigrantów.
„To jest możliwe tylko w waszej cholernej Warszawie!” O sposobie prezentacji Polski i Polaków w Miłej 18 Leona Urisa
Authors: Mazurczak Filip
Published: May 2024

Wydana w 1961 roku powieść Leona Urisa pt. Miła 18 jest jednym z najbardziej wpływowych dzieł kultury podejmujących tematykę powstania w warszawskim getcie. Pozycja ta w niezwykle niekorzystny sposób przedstawia Polaków jako niemalże genetycznych antysemitów. Autor w szczególności negatywnie obrazuje Armię Krajową oraz Kościół katolicki. Nie zaprzeczając, że w XX-wiecznej Polsce antysemityzm był rozpowszechniony, powieść Urisa często przedstawia zryw w getcie oraz szerzej, historię Polski, w sposób sprzeczny z prawdą historyczną. Mając na uwadze syjonistyczną wymowę Miłej 18 oraz innych dzieł autora, można zaryzykować tezę, że jego przeinaczenie dziejów kraju jego przodków było celowe, mające służyć budowaniu narracji proizraelskiej. Ponadto w powieści Urisa ewidentna jest obecność kliszy zwanej przez Danushę Goskę „Biegańskim”.
O znaczeniu badań nad edukacją polonistyczną w przygotowaniu kandydatów do zawodu nauczyciela
Authors: Karkut Dorota
Published: May 2024

W artykule przedstawione zostaną najważniejsze kierunki współczesnych badań nad edukacją polonistyczną, związanych z pracą nauczyciela i kompetencjami ucznia, dotyczące: czytelnictwa, tworzenia wypowiedzi ustnych i pisemnych, odbioru prozy i poezji, kształtowania postaw, a także analizy i interpretacji innych tekstów kultury. Omówione zostanie również znaczenie wyników tych badań dla kształcenia przyszłych nauczycieli we współczesnej, zmieniającej się rzeczywistości szkolnej. Głównymi problemami, którym poświęcono refleksję naukową, są sposoby upowszechniania badań ilościowych oraz jakościowych podczas konferencji naukowych organizowanych z myślą o nauczycielach (takich jak: Jesienna Szkoła Dydaktyków Literatury i Języka Polskiego w Krakowie oraz Kongres Dydaktyki Polonistycznej), jak również udział studentów w prowadzeniu mikrobadań. Zwracając uwagę na szanse i ograniczenia przydatności wyników badań nad edukacją polonistyczną w kształceniu nauczycieli, istotne okazują się także ustalenia wynikające z indywidualnych zainteresowań i doświadczeń badawczych autorki prowadzącej zajęcia ze studentami specjalności nauczycielskiej na seminarium licencjackim i magisterskim. Na potrzebę niniejszego artykułu przeprowadzone zostały badania sondażowe z wykorzystaniem kwestionariusza ankiety internetowej, których uczestnikami byli studenci specjalności nauczycielskiej.
Identification of guaiacol producing Alicyclobacillus recovered from commercial orange juices distributed in Greek markets
Authors: Sourri Patra , Dekowska Agnieszka , Bucka-Kolendo Joanna , E. Nychas George-John , C. Tassou Chrysoula , Doulgeraki Agapi
Published: May 2024

The objective of this work was the isolation and characterization of Alicyclobacillus acidoterrestris strains from orange juice. In all, 72 isolates were recovered from commercial orange juice bought from the Greek market. The isolates were subjected to polymerase chain reaction–restriction fragment length polymorphism (PCR-RFLP) to discriminate them at strain level and A. acidoterrestris types I and II. The restriction patterns of 16S rRNA gene revealed that isolates were categorized in different groups depending on the restriction endonucleases. Moreover, the digestion of the part of vdc operon gene with HphI restriction enzyme successfully differentiated between A. acidoterrestris types I and II. In conclusion, RFLP succeeded in differentiating A. acidoterrestris isolates at strain and type levels.
Por trás da inteligência artificial: uma análise das bases epistemológicas do aprendizado de máquina
Authors: Arão Cristian
Published: May 2024

Resumo: O presente artigo visa a analisar, de forma crítica, os fundamentos epistemológicos da inteligência artificial (IA). Com base no exame de obras que explicam o funcionamento dessa tecnologia, compreende-se que a sua base epistemológica é composta pelo método indutivo e pela estatística apoiada em uma matematização da realidade. São esses elementos que permitem que as máquinas aprendam através do reconhecimento de padrões e possam fazer previsões e oferecer respostas. No entanto, esses fundamentos apresentam limitações e problemas, os quais foram discutidos por filósofos, ao longo da história. Neste artigo, será demonstrado como a indução e a matematização funcionam como base epistemológica da inteligência artificial e como algumas das limitações dessa tecnologia podem ser explicadas através das debilidades dos métodos que a sustentam.
Dialéctica y aprendizaje en Theodor W. Adorno y Lev S. Vygotsky
Authors: Fallas-Vargas Fabrizio
Published: May 2024

Resumen: Este artículo aborda las relaciones entre dialéctica y aprendizaje dentro de las constelaciones de los universos conceptuales de Adorno y Vygotsky. En ese orden, se procede a analizar el conjunto de vínculos entre las principales categorías dialécticas que estructuran el enfoque dialéctico que caracteriza a ambos representantes de la tradición del pensamiento marxista (proceso, totalidad, mediación, campos de fuerza, contradictorio, praxis) y los vasos comunicantes que van desde la epistemología a la estética y que demuestran la pertinencia de las tareas del pensamiento frente a la transformación social. Finalmente, el artículo aborda la pregunta por un (im)posible horizonte analítico que surge, desde ambos pensadores, para pensar, hoy en día, enfáticamente la emancipación social y sus desafíos.
Desplazamiento semántico y contestabilidad esencial de los conceptos: un enfoque desde una negatividad hegeliana restringida
Authors: Aguilera Juan Serey
Published: May 2024

Resumen: El propósito de este artículo consiste en mostrar cómo la propuesta de W. B. Gallie en torno a la esencial contestabilidad de los conceptos políticos terminó por poner en cuestión la noción misma de contestabilidad esencial propuesta por este autor. A pesar de ello, consideramos que tal noción todavía puede ser un aporte en la historia de los conceptos si es que se complementa con algunos aspectos de la filosofía de Hegel, localizados en su Ciencia de la lógica, que pueden proveer un fundamento para tal contestabilidad a partir de una negatividad auto referida abierta a desplazamientos semánticos, lo que permite recibir la propuesta de Gallie sin tener que aceptar todos sus compromisos teóricos, radicalizando su propuesta y proporcionando algunas indicaciones de utilidad para la historia de los conceptos políticos.
Epistemologia e autonomia no conceito de ideia musical de E. Hanslick
Authors: Nachmanowicz Ricardo Miranda
Published: May 2024

Resumo: O presente trabalho aborda a filosofia estética de Eduard Hanslick, no intuito de demarcá-la enquanto abordagem epistemológica da música e um caso paradigmático para a autonomia musical. Foram analisadas as premissas epistemológicas que guiaram a obra Do belo musical, bem como as suas mais prováveis influências. Conclui-se, apresentando o conceito de ideia musical como formulação epistemológica fortemente influenciada pelo positivismo e princípio qualificador da percepção musical autônoma. Adiciona-se a essa conclusão uma desambiguação, com o conceito de ideia estética de Kant.
Arbuscular mycorrhizae in mango orchards in a Brazilian semi-arid region: influence of phenology, management and plant variety
Authors: Coelho Cauê Barbosa , Oliveira Fábio Freire de , Lima Regina Lúcia Félix de Aguiar
Published: May 2024

ABSTRACT: Arbuscular mycorrhizal fungi (AMF) increase the absorption surface of roots, providing greater absorption of water and nutrients from the soil by plants. Thus, it is important to know how arbuscular mycorrhizae are affected by factors such as phenology, management and varieties in mango (Mangifera indica) orchards in the irrigated semi-arid region. With this objective, soil and root samples were collected during the vegetative, flowering and fruiting stages, and in the water stress period before flowering, always on the same trees. The study was carried out in mango orchards of the Keitt and Palmer varieties, in agricultural farms located in Juazeiro - BA and Petrolina - PE, both under conventional management (with fertilizers and paclobutazol). The soil was used to quantify the number of AMF spores and phosphorus content. Mycorrhizal colonization in roots was evaluated in qualitative terms (presence of hyphae, vesicles and arbuscles) and quantitative terms (% of colonization). Total mycorrhizal colonization was high, with averages above 65%, and higher values in the fruiting period. Colonization by vesicles and arbuscles was on average above 45% and 17%, respectively, with higher means also during fruiting. The number of AMF spores in the soil averaged over 130 spores in 50 g of soil, with higher values in the period of water stress. The phosphorus content in the soil did not influence mycorrhizal colonization and the number of spores in the soil. The association of AMF with mango trees was generally affected by management and phenology, regardless of the cultivated varieties.
Strawberries treated with biodegradable film containing plant extracts
Authors: Gardenal A. C. , Leite A. R. Z. , Cardoso F. A. R. , Mello J. C. P. , Marques L. L. M. , Perdoncini M. R. F. G.
Published: May 2024

Abstract Strawberry (Fragaria x ananassa Duch.) is a highly perishable fruit whose characteristics make it susceptible to developing microorganisms. Plant extracts have been studied as an alternative to pesticides to control spoilage microorganisms, responding to the expectation of the population seeking a healthier way of life. The fungus Botrytis cinerea is a facultative pathogen of vegetables, which can affect all stages of the development of several fruits, such as the strawberry, where it causes gray rot. Trichilia catigua (catuaba), Paullinia cupana (guarana), Stryphnodendron barbatiman (barbatimão), and Caesalpinia peltophoroides (sibipiruna) are planted in the Brazilian flora and have demonstrated pharmacological properties in their extracts. This work aimed to treat strawberries with a biodegradable film containing extracts of these species to evaluate strawberry conservation. There were notable distinctions in mass loss between the extract-treated and control samples. The pH, total acidity (TA), and soluble solids parameters exhibited consistently significant means across both sets of samples. Luminosity increased over the course of days in the color parameters, with the exception of strawberries coated with guarana. The red color showed greater intensity, except for those coated with barbatimão extract. Considering the results, it is possible to conclude that the coatings used can become an alternative to enhance the conservation of strawberries.
Effect of coated urea and NPK-fertilizers on spring wheat yield and nitrogen use efficiency
Authors: Lapushkin V. M. , Lapushkina A. A. , Torshin S. P.
Published: May 2024

Abstract Among the factors that increase the efficiency of mineral fertilizers, due consideration has lately been given to the development and study of fertilizers with various granule coatings. This study is focused on the test of urea and NPK fertilizers, with granules coated with 50 and 100 μm monocalcium phosphate. Two-year greenhouse trials with spring wheat were carried out on soddy-podzolic light loamy soil. Coated fertilizers have proven to be more effective than traditional ones. For instance, using coated urea improved the yield 10-11% compared to conventional fertilizer. At the same time, the weight of one plant increased by 9-11% and the weight of the ear by 10%, the number of grains in the ear was by 4-7% bigger. Similar results were obtained with NPK fertilizer. Providing a thicker coating from 50 to 100 μm significantly increased the efficiency of both urea and NPK fertilizers.
Feeding ecology of the Red-and-green Macaw (Ara chloropterus; Gray 1859) in a habitat mosaic from Cerrado
Authors: Ragusa-Netto J.
Published: May 2024

Abstract In the Brazilian Cerrado, the Red-and-green Macaw (Ara chloropterus) populations are facing an accelerated rate of habitat loss. Despite this, their feeding areas and primary food sources remain poorly understood. In this study, I assessed the relationship between the diet of the Red-and-green Macaw and available food resources in a habitat mosaic from the fragmented Cerrado in Mato Grosso do Sul State, Brazil. Red-and-green Macaws fed on 20 native and five exotic species, mainly in dry habitats (Cerrado, dry forest, and an urban area along the Maracaju Cliffs) during the dry season, while year-round foraging in the riparian vegetation (Aquidauana River and streams). Then, the number of feeding macaws paralleled variations in food abundance and diversity, besides the number of food species. On the other hand, by using a wide variety of abundant foods, macaws' diet breadth presented high values throughout the year. The seasonal consumption of large-seeded fruits across the habitat mosaic displayed a gradient ranging from the urban area to dry habitats, along which macaws ate from exotic to Cerrado species. In this respect, Terminalia catappa seeds and Mangifera indica fruit pulp were important for Red-and-green Macaws in the urban area during the wet season, while Caryocar brasiliense seeds comprised the same in the Cerrado. At this site, both Dipteryx alata and Buchenavia tomentosa seeds composed much of the Red-and-green Macaws' diet during the dry season. Between those habitats, in the watercourse vegetation, macaws frequently foraged on palm fruits across seasons. Therefore, throughout the year, the abundance and variety of food resources strongly influenced the number of foraging Red-and-green Macaws across the habitat mosaic. Understanding the effect of varying seed availability on the spatial and temporal abundance patterns of Red-and-green Macaws, which primarily feed on large-seeded species, is central to developing effective conservation strategies. Due to the accelerated habitat loss, the Maracaju Cliffs emerge as crucial for the Red-and-green Macaw among the Cerrado remnants of Mato Grosso do Sul.