bluuebunny/crossref_metadata_2025 huggingface dataset:
SiExo: An AI-Driven Exosome Platform for Precision siRNA Delivery in CNS Disorders
Authors: Basanth Samarth
Published: February 2025

Neurodegenerative diseases, including Huntington’s disease, Alzheimer’s disease, and Parkinson’s disease, are among the most challenging disorders to treat due to the restrictive nature of the blood-brain barrier (BBB), which blocks over 98% of potential therapeutics. Small interfering RNA (siRNA) presents a promising gene-silencing strategy, but clinical translation is hindered by degradation, off-target effects, and poor BBB permeability.This study presents SiExo, an AI-driven siRNA-loaded exosome platform engineered for high-efficiency CNS delivery. By integrating machine learning, molecular dynamics simulations, and Bayesian optimization, SiExo refines exosome lipid composition, ligand density, and siRNA stability for optimal therapeutic effect. Dual-ligand functionalization with transferrin and rabies virus glycoprotein enhances receptor-mediated BBB transcytosis, achieving a 3.5-fold increase in BBB penetration over unmodified exosomes. Functional testing in hCMEC/D3-based in vitro BBB models confirmed a 32% penetration rate (compared to 12% in controls, p < 0.01).AI-driven exosome design outperforms conventional lipid nanoparticles and viral vectors, yielding 2.8-fold greater siRNA retention and 1.9-fold higher neuron-specific uptake. In Huntington’s disease models, SiExo-mediated siRNA delivery resulted in a 62% reduction in mutant HTT mRNA expression, demonstrating significant gene-silencing potential. Bayesian optimization identified optimal exosome configurations with 92% predictive accuracy, accelerating non-immunogenic, patient-specific exosome engineering.This study establishes SiExo as a scalable CNS gene therapy platform, capable of supporting CRISPR/Cas9-based interventions for neurodegenerative and neuroinflammatory disorders. Future work will focus on in vivo validation and preclinical translation using patient-derived neural organoids and primate models, bridging the gap toward next-generation precision medicine for CNS disorders.
Request for divorce by the exclusively guilty spouse in Poland
Authors: Sobanski Piotr
Published: February 2025

The finding that the marital breakdown has reached a state allowing it to be described as permanent and complete is a necessary condition for a divorce judgment (Article 56 § 1 of the Polish Family and Guardianship Code). The durability and completeness of the breakdown are positive conditions for divorce that are interrelated. However, according to Article 56 § 3 of the Family and Guardianship Code, even in the case of a complete and permanent breakdown of the marital relationship, divorce is not permissible if it is requested solely by the spouse at fault for the breakdown of the marriage, unless the other spouse consents to the divorce or the refusal of their consent in the given circumstances contradicts the principles of social coexistence. Determining the causes of the breakdown of marital relations is necessary for determining which spouse is at fault for the breakdown of the marriage. According to the judgment of the Supreme Court of 4 October 2001, I CKN 871/00: "The determination of the spouse's fault in the breakdown of the marriage in the divorce judgment is not a consequence of a specific assessment of evidence, but a legal conclusion drawn from established facts, expressing at the same time a negative assessment of the spouse's conduct that led to the breakdown." (...) Kancelaria Adwokacka Adwokat dr Piotr Sobański LL.M. Plac Pocztowy 6/4 Zielona Góra Polska piotr.sobanski@adwokatura.pl ORCiD: 0000-0001-8303-1125
Anxiety and Future-Self Clarity: Can Future Thinking Influence Self-Esteem?
Authors: Duffy Jessica , Salt Grace , Cole Scott , Charura Divine , Shevchenko Jennifer
Published: February 2025

Possible selves reflect one’s hopes and fears for their future identity. Previous research shows that high anxiety is associated with clearer feared possible selves. However, the mechanism through which clarity could maintain anxiety is relatively unexplored as are questions concerning whether clarity of possible selves could offer new methods of reducing anxiety. The present article aimed to investigate if the relationship between clarity and anxiety is mediated by self-esteem. In addition, the present study aimed to explore the impact of the Best Possible Self-Technique on anxiety. In line with predictions, it was found that the relationship between the clarity of feared possible selves and anxiety was mediated by self-esteem. In addition, a preliminary exploration (using a repeated measures design) showed potential benefits for using a Best Possible Self-Technique in reducing anxiety. Overall, these findings provide insights into a potential mechanism through which the clarity of feared possible selves could influence anxiety, namely, through reducing self-esteem. Also, the findings open new avenues for future interventions designed to reduce anxiety through targeting the clarity of thoughts concerning future selves.
Trajectories of conduct problems: exploring genetic and early-life risk factors and adult outcomes
Authors: Palaiologou Elisavet , Viding Essi , Bright Joanna K , Assary Elham , Breen Gerome , Hotopf Matthew , Lockhart Celestine Laetitia , Skelton Megan , Stringaris Argyris , Carr Ewan , Eley Thalia Catherine
Published: February 2025

Background: Conduct problems trajectory studies suggest their development is highly heterogeneous and that different trajectories may be uniquely associated with different risk factors and outcomes. Yet studies combining trajectory modelling and a varied set of genetic and early-life risk factors, as well as adult outcomes, are scarce. Methods: We analysed data from the Twins Early Development Study (TEDS), a longitudinal UK twin cohort (N=18,993). Conduct problems were measured using parent reports of the Strengths and Difficulties Questionnaire (SDQ) conduct problems subscale at four time points between ages 4 and 12. Trajectories were identified using growth mixture modelling. We then explored associations between trajectory class membership and genetic and early-life factors (age 4), and adult life and clinical outcomes (age 26). Results: Four conduct problem trajectories were identified: Low Stable (n=15,304, 81%), Childhood-Limited (n= 1,395, 7%), Childhood-Increasing (n=1,791, 9%) and Persistent (n=503, 3%). Associations with risk factors followed a stepped pattern with individuals in the Persistent class reporting higher genetic liability and early-life risk. Higher genetic vulnerability to attention-deficit hyperactivity disorder distinguished between the Low Stable and all other classes. Higher externalising problems polygenic score, negative family environment and hyperactivity/inattention, distinguished between all classes, except the Childhood-Increasing and the Childhood-Decreasing ones. Children experiencing conduct problems in childhood were at higher risk for reporting poorer current and lifetime mental and physical health outcomes, lower educational attainment and financial difficulties.Conclusions: Children experiencing conduct problems face multiple risk factors that should be addressed. Previously identified risk factors (i.e. negative family environment, hyperactivity/inattention), continued to differentiate between all classes after accounting for various psychiatric polygenic scores, validating existing interventions targeting these factors. Childhood conduct problems were associated with poor outcomes in adulthood, emphasising the need to develop interventions identifying those at risk early.
The way of thinking about depressive symptoms using exponential distribution (exponential process) and Poisson process
Authors: Yabu Takuya
Published: February 2025

So far, we have used stochastic differential equations to explain the process that leads to feelings and thoughts that assume a Wiener process. In reality, however, depressive symptoms may suddenly appear when one is feeling at ease. When a person is suffering from depression, the value of a group of curves, such as the person's similarity curve, is at a negative minimum if we consider the Wiener process. However, a person may go from being at ease to being depressed, i.e., the value of the similarity curve or other curve group may suddenly go from a positive value to a negative minimum. This cannot be explained by the conventional concept of similarity curves and other curve groups using the Wiener process. Therefore, we considered depressive symptoms using exponential distribution (exponential process) and Poisson process. We derived the stochastic differential equation given for the time when the person is not depressed, and showed that the time when the person is not depressed is an exponential distribution (exponential process). We also derived an exponential distribution (exponential process) for the number of times a person becomes depressed during a certain period of time, and showed that the number of times a person becomes depressed during a certain period of time is a Poisson process. Based on these results, we explained the relationship between the number of times a person becomes depressed during a certain period of time and the time when he or she is not depressed. We also discussed the connection with similarity curve and other results in the previously discussed paper. Finally, he stated that placing oneself in an environment or state where one is less likely to become depressed is a way to cope with depression.
Direct and indirect genetic effects on educational achievement vary across countries and ages
Authors: Starr Alexandra , Ruks Mirko , Giannelis Alexandros , Willoughby Emily A , Pettersson Oskar , Pahnke Charlotte Katharina Louise , Maj Carlo , Andreas Anastasia , Ahlskog Rafael , Arseneault Louise , Fisher Helen Louise , Forstner Andreas , Kandler Christian , McGue Matt , Nöthen Markus , Oskarsson Sven , Spinath Frank M. , VRIEZE SCOTT , Wertz Jasmin , von Stumm Sophie
Published: February 2025

Polygenic score (PGS) predictions of educational achievement are sizeable at population level. They capture so-called ‘direct’ genetic effects that are independent of environmental confounding, but also ‘indirect’ genetic effects due to gene-environment correlations, assortative mating, and population stratification. Indirect genetic effects complicate the interpretation and application of PGS predictions. Here, we systematically charted the variability of PGS predictions in N=8,115 dizygotic twins from UK, US, Swedish, and German samples aged 7 to 19 years. Population-level PGS predictions of educational achievement ranged from beta =.16 to .37 across ages and countries. Indirect genetic effects due to environmental confounding accounted for 10% to 65% of the population-level PGS predictions, with family socioeconomic status explaining 29-100% of these indirect genetic effects. Variability in direct and indirect genetic effects was largely unsystematic across countries’ school systems (multi-tiered vs. comprehensive) and children’s ages. Therefore, interpretations of indirect genetic effects on educational achievement remain, at present, speculative.
The InterModel Vigorish (IMV) as a flexible and portable approach for quantifying predictive accuracy with binary outcomes
Authors: Domingue Benjamin , Rahal Charles , Faul Jessica , Freese Jeremy , Kanopka Klint , Rigos Alexandros , Stenhaug Ben , Tripathi Ajay
Published: February 2025

Understanding the ``fit'' of models designed to predict binary outcomes has been a long-standing problem. We propose a flexible, portable, and intuitive metric for quantifying the change in accuracy between two predictive systems in the case of a binary outcome: the InterModel Vigorish (IMV). The IMV is based on an analogy to weighted coins, well-characterized physical systems with tractable probabilities. The IMV is always a statement about the change in fit relative to some baseline model---which can be as simple as the prevalence---whereas other metrics are stand-alone measures that need to be further manipulated to yield indices related to differences in fit across models. Moreover, the IMV is consistently interpretable independent of baseline prevalence. We contrast this metric with alternatives in numerous simulations. The IMV is more sensitive to estimation error than many alternatives and also shows distinctive sensitivity to prevalence. We then showcase its flexibility across examples spanning the social, biomedical, and physical sciences. We also demonstrate how it can be used to provide straightforward interpretation of logistic regression coefficients. The IMV allows for precise answers to questions about changes in model fit in a variety of settings in a manner that will be useful for furthering research with binary outcomes.
Changing Dynamics of Politics in Nepal: How Do Women Fear Party Politics?
Authors: Dahal Kabita
Published: February 2025

Democracy is a political system that requires the participation of all citizens in the political process, including women in leadership roles. Successful democratization depends on ensuring women's full engagement in politics. This study investigates the apprehensions and systemic barriers that impede women’s political participation in Nepal. This study used a swift questionnaire survey combined with a Likert scale analysis to examine the perceptions of 156 women from diverse socio-economic backgrounds regarding both established and emerging political parties. The findings highlight that, despite feminist rhetoric from some parties, women's participation is significantly undermined because of concerns about harassment, political violence, and the potential for community reprisal. This resistance stems from deep-seated historical, social, and structural factors, leading to the marginalization of women. Notably, women from the informal sector and younger women reported higher levels of fear. In contrast, emerging parties were perceived as more responsive to women's concerns. This research emphasizes the urgent need for a secure and inclusive political environment that supports non-violent and meaningful representation of women. To achieve this, a concerted effort is required to address systemic barriers and patriarchal norms; develop gender-sensitive policies that empower women politically; and ultimately facilitate gender equity and a more inclusive, fair, and genuinely representative democracy in Nepal.
Development for Geopolitics and Geopolitics Through Development Perspectives from Nepal
Authors: Bhatta Chandra Dev
Published: February 2025

This article examines the connection between development and geopolitics in Nepal. The primary assertion made here is that development cannot be viewed solely through its principles, as commonly perceived, but is also significantly shaped by geopolitical motivations. It investigates the interactions among geopolitics, non-state entities, and foreign aid, offering a systematic qualitative evaluation. It also explores the relationship between development and geopolitics, indicating that development frequently hinges more on geopolitical factors than on the process of development itself. This might clarify why, despite continuous external assistance and internal initiatives, development has not advanced to a stage that can offer economic opportunities for all individuals. Support and initiatives for development from the outside often reflect an external perspective on Nepal's progress. Furthermore, development in Nepal has become highly (geo)politicized and the country struggles to determine which projects to undertake and which to avoid this trend will continue in the coming days as well. It contends that Nepal must take a proactive approach to tackling existing geopolitical issues while furthering its development goals.
Soft Power of Asian Land-Locked Countries: A Comparative Study of Nepal and Mongolia
Authors: Pant Rashmi
Published: February 2025

This study explores how Nepal and Mongolia, two landlocked Asian countries, utilize their soft power resources to overcome geographical limitations and advance their national interests. The research examines the concept of soft power, its application in both developed and developing countries, and how Nepal and Mongolia have adopted distinct strategies to address their landlocked status. Using context and policy analysis, the study highlights Nepal's active border engagement policy to overcome the landlockedness issue, which includes creating pan-regional networks, prioritizing mini-lateral initiatives, establishing spiritual circuits, diversifying exchanges, and promoting its unique cultural festivals. In contrast, Mongolia focuses on its "Third Neighbor Policy," engagement in international organizations, promotion of its historical legacy, and branding itself as a developmental state. The findings suggest that while both countries face similar challenges, their strategies differ significantly, offering valuable lessons for other landlocked nations.
Experimental Study of Steel and Polypropylene Fiber Reinforced Concrete
Authors: Karna Shrutee , Baniya Arjun
Published: February 2025

Fiber-reinforced concrete (FRC) is a composite material incorporating cement, sand, coarse aggregates, and fibers. FRC use both natural and artificial fibers as reinforcement to improve the mechanical properties. This study investigated the effects of two types of artificial fiberssteel and polypropylene—on concrete properties. Steel fiber reinforced concrete (SFRC) with 2% fiber by volume and polypropylene fiber reinforced concrete (PFRC) with 1.5% fiber by volume were prepared. A total of eighteen specimens were made using M20 grade concrete: six cubes, six cylinders, and six beams for each type of fiber. Mechanical properties were tested under compression, including compressive strength, split-tensile strength, and flexural strength. Results showed that PFRC with 1.5% polypropylene fiber exhibited a 23.4% increase in compressive strength, a 32.2% increase in split-tensile strength, and a 20% increase in flexural strength compared to conventional concrete. SFRC with 2% steel fiber demonstrated a 27.2% increase in compressive strength, a 42.7% increase in split-tensile strength, and a 35.8% increase in flexural strength compared to conventional concrete.
CFD Analysis of Rear Spoiler Effects on Vehicles Aerodynamic Performance
Authors: Badu Prajash , Panjiyar Rahul , Guragain Kushal , Yadav Pankaj
Published: February 2025

This study explores the aerodynamic properties of a sports car model, focusing on the impact of rear spoilers on vehicle's performance. Two car models are evaluated using the Computational Fluid Dynamics (CFD) simulation approach. The first basic model lacks a rear spoiler, whereas the second superior model features a rear NACA 2412 airfoil spoiler. The simulation was conducted at the indicated velocities: 100 km/hr., 180 km/hr., and 240 km/hr. to determine the impact of the spoiler, specifically drag force, lift force, and performance. The investigation shows that when a vehicle is traveling at a high speed, the rear spoiler increases stability and control by producing a significant amount of drag and down force. However, when the velocities are high, there is a rapid increase in drag force accompanied with an increase in lift coefficient, indicating that the spoiler has certain restrictions at high speeds. This can be a trade-off, as some researchers have discovered that a tiny increase in drag force results in an increase in down force. Overall, the advantages include stability and safety of the vehicle fleet. As a result, the study concludes that rear spoilers are critical in providing the appropriate level of downforce and reduced drag to the sports vehicle while also increasing overall road control, safety, and efficiency.
Museum Pedagogy in the 21st Century: Tradition and Modernity (in the year of the 270th anniversary of Lomonosov Moscow State University and the 80th anniversary of the Great Victory)
Authors: Sabodina Evgeniya Petrovna
Published: February 2025

The chapter shows a number of achievements of Russian soil science in the works of Academician of the Russian Academy of Sciences G. V. Dobrovolsky and Laureate of the State Prize of the Russian Federation E.D. Nikitin from the point of view of updating and expanding the exposition of the Department of Natural Zonality and Soil Science of the Space Earth Sciences and Rational Nature Management sector of the Lomonosov Moscow State University.
Metaphorical associative maps as a tool for psychological help to students
Authors: Kozlova Mariia Aleksandrovna , Kozlov Aleksei Vladimirovich
Published: February 2025

The phenomenon of the impact of metaphorical associative cards remains poorly understood in modern scientific and methodological literature. At the same time, the effectiveness of their impact and the lack of knowledge of the psychological mechanisms and principles of operation of MAC (metaphorical associative cards) encourage the imagination of students and clients to attribute them to a mystical realm, comparing them with Tarot cards. This chapter will be useful for practical psychologists, educators, psychotherapists, specialists in related fields of art therapy, art pedagogy, and anyone interested in metaphorical associative cards as an effective art therapeutic tool.
Inflation and Economic Growth in the Sudan: An Empirical Analysis
Authors: Elhassan Mohieldin Ali , Talha Gamaleldeen Osman
Published: February 2025

Objectives: The study's objective is to investigate the relationship between inflation and economic growth in Sudan from 1982 to 2020. Methods: To achieve this objective, the study co-integration analysis within an auto-regressive distributed lag (ARDL) methodology. The bound test revealed that the model's variables are co-integrated in the long term, with the significance of the error correction term further confirming this long-term relationship, while the ERC should focus on short-term dynamics. Results: The results indicate that the growth rate of real GDP per capita is positively and significantly co-integrated with the growth rate of capital per capita, whereas it is negatively and significantly co-integrated with the inflation rate. Conclusions: The study recommends that policymakers consider this inverse relationship when formulating economic policies.
ANALISIS KEPATUHAN WAJIB PAJAK USAHA MIKRO KECIL DAN MENENGAH USAHA WARUNG KOPI DI KOTA PAREPARE
Authors: Putri Sulistya Ningrum Farzyah , Abdillah Muhammad Abdian
Published: February 2025

Kepatuhan Wajib Pajak dalam Penelitian ini bertujuan untuk mengetahui sejauh mana kepatuhan wajib pajak pada usaha mikro, kecil, dan menengah (UMKM) warung kopi di Kota Parepare. Metode yang digunakan dalam penelitian ini adalah metode deskriptif dengan pendekatan kuantitatif, yang mengumpulkan data melalui penyebaran kuesioner kepada pemilik warung kopi. Populasi dalam penelitian ini adalah seluruh warung kopi di Kota Parepare yang berjumlah 60 warung, dan sampel yang diambil sebanyak 40 warung kopi yang dipilih berdasarkan kriteria memiliki banyak pengunjung dan terpopuler saat ini. Hasil penelitian menunjukkan bahwa tingkat kepatuhan wajib pajak UMKM pada usaha warung kopi di Kota Parepare masih tergolong rendah. Hal ini terlihat dari banyaknya pemilik warung kopi yang belum mendaftarkan diri sebagai wajib pajak, belum melaporkan Surat Pemberitahuan (SPT) Masa, serta belum membayar pajak tepat waktu. Faktor-faktor seperti kurangnya pemahaman tentang kewajiban perpajakan, minimnya sosialisasi mengenai pajak, dan kesadaran yang rendah dari pemilik usaha menjadi penyebab utama rendahnya kepatuhan pajak di kalangan pemilik warung kopi. Oleh karena itu, dibutuhkan peningkatan edukasi perpajakan dan pengawasan yang lebih ketat dari instansi terkait untuk meningkatkan tingkat kepatuhan wajib pajak UMKM di Kota Parepare.
ANALISIS PERAN AUDIT MANAJEMEN SEBAGAI PENILAIAN PENINGKATAN EFISIENSI DAN EFEKTIVITAS KINERJA FUNGSI PRODUKSI LEMON PADA PT. AL FATIH PORANG INDONESIA
Authors: Hasdiana Hasdiana , Rahma Rika , Rina Rina
Published: February 2025

Audit manajemen yang berfungsi sebagai alat ukur bagi perusahaan untuk dapat membantu menilai atau meningkatkan ekonomisasi, efektivitas, dan efisiensi kinerja manajemen perusahaan. PT. Al Fatih Porang Indonesia merupakan perusahaan bergerak dibidang industri pertanian terkhususnya pada produksi sari lemon. Penelitian ini bertujuan untuk mengetahui peran audit manajemen sebagai penilaian peningkatan efisiensi dan efektivitas fungsi produksi sari lemon dari indikator-indikator ruang lingkup audit manajemen produksi pada PT. Al Fatih Porang Indonesia. Penelitian ini merupakan metode penelitian deskriptif  kualitatif. Teknik pengumpulan data yang digunakan dalam penelitian yaitu observasi, wawancara dan dokumentasi. Adapun beberapa tahapan audit yang terdiri dari survei pendahuluan, review  dan pengujian pengendalian manajemen serta pengujian terinci. Hasil penelitian ini menunjukkan bahwa aktivitas produksi sari lemon pada PT. Al Fatih Porang Indonesia cukup efisien dan efektif. Hal ini, ditunjukkan dari hasil beberapa indikator dari ruang lingkup audit manajemen produksi yang sebagai acuan penilaian pengujian pengendalian manjemen, meskipun perusahaan memiliki beberapa kendala terutama pada bahan baku yang tidak menentu diterima dari petani.
PENGARUH LITERASI KEUANGAN TERHADAP PENGELOLAAN KEUANGAN UMKM DI KECAMATAN SOREANG KOTA PAREPARE
Authors: Hasdiana Hasdiana , Melda Melda
Published: February 2025

Gambaran awal yang diperoleh bahwa sebahagian besar dari Pelaku UMKM pada dasarnya belum mampu melakukan pencatatan keuangan sesuai dengan prinsip-prinsip yang dijadikan acuan dalam pengelolaan keuangan. Walaupun dari hasil observasi awal ini ditemukan bahwa beberapa pelaku UMKM telah mampu menerapkan sistem Digitalisasi dalam hal Transaksi, namun hal tersebut belum mampu memberikan gambaran secara utuh bahwa usaha tersebut telah melakukan pencatatan atas keuangan yang dikelola. Serta dari beberapa pertanyaan awal yang diajukan dapat disimpulkan bahwa para pelaku UMKM memahami tentang pentingnya sebuah pencatatan hanya saja dalam pengimplementasiannya belum mampu dilakukan secara maksimal Penelitian ini menggunakan Metode Kuantitatif dengan jumlah Responden sebanyak 170 orang, adapun alat analisis yang digunakan yakni SPSS (Statistical Package for the Social Sciences). Hasil dari penelitian ini menunjukkan bahwa Pengetahuan, Sikap dan Perilaku Keuangan berpengaruh secara signifikan terhadap Pengelolaan Keuangan UMKM di Kecamatan Soreang Kota Parepare, dari hasil ini diketahui pula bahwa Literasi Keuangan dari Pelaku UMKM dapat dikatakan cukup baik
PENGARUH LINGKUNGAN KERJA DAN BEBAN KERJA PEGAWAI TERHADAP KUALITAS PELAYANAN PADA LEMBAGA PERMASYARAKATAN KELAS IIA PAREPARE
Authors: Shelviani Shelviani
Published: February 2025

Abstrak
Tingginya tuntutan terhadap pemberian kualitas pelayanan terbaik kepada Warga Binaan Pemasyarakatan (WBP) dengan kondisi tingkat kepadatan hunian yang melebihi kapasitas membuat hampir semua petugas dan pegawai Rumah Tahanan Negara (Rutan) atau Lembaga Pemasyarakatan (Lapas) mengalami kelebihan beban kerja. Kondisi semacam ini tentunya akan memberikan dampak negatif yang akan berimbas pada kualitas pelayanan yang diberikan. Penelitian ini bertujuan untuk mengetahui pengaruh Beban Kerja dan Lingkungan Kerja jika secara bersama-sama terhadap Kualitas Pelayanan pada  Lembaga Pemasyarakatan Kelas II.A Parepare. Penelitian ini menggunakan Metode Kuantitatif dengan jumlah Responden sebanyak 77 orang, adapun teknik pengumpulan data ada tiga yaitu observasi, kuesioner dan studi kepustakaan.  Alat analisis yang digunakan yakni SPSS (Statistical Package for the Social Sciences) Versi 25. Hasil dari penelitian ini menunjukkan bahwa Beban Kerja dan Lingkungan Kerja baik secara Parsial maupun Simultan berpengaruh secara signifikan terhadap Kualitas Pelayanan pada Lembaga Permasyarakatan Kelas IIA Parepare artinya bahwa Beban Kerja dan Lingkungan Kerja dianggap mampu saling melengkapi dalam menciptakan pelayanan yang berkualitas.
ANALISIS CASHFLOW TERHADAP PERKEMBANGAN UMKM DI KOTA PAREPARE
Authors: Jumriani Jumriani , Yusuf Muhammad Khadavy
Published: February 2025

Analisis cash flow (arus kas) terhadap perkembangan UMKM (Usaha Mikro, Kecil, dan Menengah) adalah proses untuk memahami bagaimana aliran uang masuk dan keluar dapat memengaruhi pertumbuhan dan keberlanjutan usaha. Cash flow yang sehat sangat penting bagi UMKM karena bisnis dalam kategori ini umumnya memiliki keterbatasan modal dan akses pembiayaan. Dengan demikian, manajemen arus kas yang baik menjadi salah satu kunci keberhasilan UMKM. Penelitian ini bertujuan untuk mengetahui peran dan kendala  cashflow terhadap perkembangan UMKM di Kota Parepare. Adapun teknik pengumpulan data yang digunakan dalam penelitian ini yaitu wawancara, observasi dan dokumentasi, sumber data dalam penelitian ini yaitu kepala atau staf dinas tenaga kerja Kota Parepare, serta pelaku UMKM di Kota Parepare. Teknik analisis data dalam penelitian ini menggunakan reduksi data, penyajian data, interpretasi data, dan penarikan kesimpulan. Hasil penelitian menunjukkan bahwa peran cashflow terhadap perkembangan UMKM di Kota Parepare adalah: 1. Mengatur dan memprediksi keuangan, 2. Menghemat biaya dan meningkatkan profit, 3. Meningkatkan keterampilan, 4. Meningkatkan pengambilan keputusan. Adapun kendala dalam pengimplementasian cashflow terhadap perkembangan UMKM di Kota Parepare adalah: 1. Ketidakmampuan dalam pengelolaan cashflow, 2. Kurangnya SDM yang Kompeten.
The Influence Of Total Quality Management And Raw Material Quality On Cost Efficiency In Coffee Shops In Makassar City
Authors: Utari Nur Umrah  , Suryanti Suryanti , Hafid Normadia , Utama Riyanda Putra
Published: February 2025

Cost efficiency aims to improve profitability by reducing unnecessary costs, such as rework costs or losses due to defective products, while ensuring that products or services remain of high quality. This study aims to examine the influence of the implementation of total quality management and raw material quality on cost efficiency in coffee shops in Makassar City. The data in this study were obtained from coffee shops located in Makassar City that agreed to participate as respondents. This research uses primary data by conducting field research, distributing questionnaires/statements to 90 respondents. The data analysis method employs a specialized multiple linear regression analysis application with a quantitative approach. The results of this study indicate that: (1) The hypothesis test results show that the variable of total quality management implementation has a positive and significant effect on improving cost efficiency in coffee shops in Makassar City. (2) The hypothesis test results show that the variable of raw material quality has a positive and significant effect on cost efficiency in coffee shops in Makassar City.
Service Quality, Customer Relationship Management, and Brand Image On Consumer Decisions (Expedition Services In Solo City)
Authors: Romadhoni Khoiruddin  , Nasir Moechammad
Published: February 2025

This study is intended to analyze the impact of service quality, customer relationship management, and brand image on consumer decisions regarding the use of expedition services in Solo City. This study uses an explanatory research type with a quantitative method measured using a Likert scale. The data analysis in this research utilizes SPSS version 23. The sample for this research refers to the calculation by Hair et al. (2010), which involves multiplying the total number of indicators in this study by a range of 5 to 10. This study uses 17 question indicators, resulting in a calculation of 17 multiplied by 6, which equals 102. Therefore, a sample of 102 respondents was used. The data collection technique employed was distributing questionnaires via Google Forms. Additionally, the collected respondent data will be classified according to gender, age, education, occupation, and income level. The research results indicate that the variables of service quality, customer relationship management, and brand image have a positive and significant impact on the decision to use expedition services in Solo City.
The Influence of the Self-Assessment System and MSME Income Turnover on MSME Taxpayer Compliance with Emotional Intelligence as a Moderating Variable (A Case Study at KPP Pratama Makassar Utara)
Authors: Nungki Prawita Sari  , Syamsu Alam  , Muhammad Syafii Basalamah
Published: February 2025

MSMEs in Indonesia are required to pay final taxes in accordance with Government Regulation No. 23 of 2018, with a tax rate of 0.5% of gross turnover. This obligation is designed to simplify the taxation process for MSMEs. This study aims to examine the influence of the Self-Assessment System and MSME Income Turnover on MSME Taxpayer Compliance, with Emotional Intelligence as a Moderating Variable. The data for this research were obtained from MSME taxpayers registered at KPP Pratama Makassar Utara who agreed to participate as respondents. This study utilized primary data collected through field research by distributing questionnaires/statements to 92 respondents. Data analysis was performed using descriptive statistical analysis and PLS (Partial Least Square). The results of the study indicate that the Self-Assessment System and MSME Income Turnover have a positive and significant effect on MSME Taxpayer Compliance. Furthermore, the positive and significant effect of the Self-Assessment System and MSME Income Turnover on MSME Taxpayer Compliance is strengthened by Emotional Intelligence.
EXTRAPOLATION OF THE NORTHERN AMERICAN EXPERIENCE OF ADULT EDUCATION DEVELOPMENT IN NATIONAL EDUCATIONAL SPACE
Authors: TERENKO OLENA , KLOCHKO LARISA
Published: February 2025

Nowadays informal adult education is viewed as a means of adults educational needs fulfilment, their perfection and self-development and as a mechanism of democratic society formation, for it helps to form socially active citizens, who are mobile in professional and social contexts to rapid changes in social environment. Key concepts in American and Canadian state and society formation are «activity», «civil society», «democratic society». Movement for civil rights is the most vivid social phenomenon in Canadian and American history. The aim of the article is to work out recommendations concerning creative application of positive American and Canadian experience in reformation of national system of adult education. For fulfilment of the mentioned aim the following methods are applied: a system of general theoretical methods in particular analysis, synthesis, comparison, abstraction, concrete scientific methods in particular term analysis and historical genetic analysis. Analysis of peculiarities of adult education development in different historical periods in Ukraine is conducted. Adult education as an important element of civil society formation in the USA and Canada is viewed. Analysis of concepts «active citizenship» and «democratic citizenship» is conducted. Principles of informal adult education are systematized. Recommendations concerning creative application of positive ideas of American and Canadian experience in national adult education system are worked out. Results of the conducted research work give opportunity to state that American and Canadian experience in the field of adult education can help to create harmony between national traditions and world achievements on the basis of humanism and democracy; to give high quality educational service to adults, synchronize national system of adult education with world tendencies, provide conditions for adult education development and its influence on economic development of state.
DEVELOPMENT OF DIGITAL LITERACY AND PROBLEM-SOLVING SKILL-INFUSED ENGLISH READING MATERIALS FOR SENIOR HIGH SCHOOL STUDENTS. A NEED ANALYSIS
Authors: Hapizah Siti Nurul , Sulistyaningrum Siti Drivoka
Published: February 2025

This study aims to analyze the English reading materials currently used by senior high school students and evaluate the extent to which they incorporate digital literacy and problem solving. The study was conducted at a senior high school in Bekasi, Indonesia. The research employs qualitative content analysis to examine the existing English reading materials, which consist of English textbooks. Furthermore, interviews with three English teachers were conducted to explore the needs of learning materials further. The findings reveal a gap between the current materials and the descriptors of digital literacy and problem solving. Therefore, it indicates an urgency to develop new English reading materials that promote problem solving and incorporate digital literacy to better facilitate the studentsâ€™ needs.
STUDENTS’ ENGAGEMENT IN ENGLISH FOR SPECIFIC PURPOSES (ESP) GROUP DISCUSSIONS: A CASE STUDY AT A UNIVERISTY
Authors: Barella Yusawinur , Safitri Isnaini Nur , Asri Anindhiasti Ayu Kusuma
Published: February 2025

English for Specific Purposes (ESP) constitutes a pedagogical approach to English language acquisition. It provides students by learning language in a certain context. Studies on implementing group discussion have been done, but not focusing on their engagement. Thus, this study investigates student engagement in English for Specific Purposes (ESP) group discussions at a university level. ESP courses are designed to meet the specific language needs of students in professional or academic contexts, enhancing their communication skills relevant to their fields. The research employs a qualitative methodology, utilizing thematic analysis to explore students' experiences and perspectives. Data were collected through classroom observations and interviews with eight undergraduate students from two higher education institutions in Indonesia. The findings reveal that group discussions in ESP classes significantly enhance students' oral communication skills, teamwork, and problem-solving abilities. However, challenges such as unequal participation and language anxiety were also identified. The study underscores the importance of effective moderation and structured discussions to ensure equitable participation and maximize engagement. These insights have practical implications for improving instructional strategies in ESP courses, ultimately fostering a more engaging and effective learning environment.Keywords: English for Specific Purposes, group discussion, students’ engagement
EXPLICIT INSTRUCTION: A METHOD TO ENGAGE STUDENTS IN ENGLISH AS A FOREIGN LANGUAGE (EFL) SOURCE-BASED WRITING
Authors: Maulidiyah Noor
Published: February 2025

Academic writing is a crucial subject for university students to equip them with the necessary skills for writing academic research papers. However, writing is a particularly complex skill for a second language and foreign language learners to learn. University students may lack background knowledge about English writing, particularly writing based on sources. Source-based writing is a fundamental academic writing skill in universities. It includes the skills of paraphrasing, summarizing, and synthesizing. English as a Foreign Language (EFL) learners may face difficulties in producing such writing which could lead to higher practices of plagiarism and academic misconduct. These practices of plagiarism and academic misconduct could be minimized by explicit instruction on source-based writing in Academic Writing courses. This paper argues that explicit instruction is an effective method for teaching source-based writing. The paper aims to explore the concept of explicit instruction in teaching and learning EFL source-based writing. The writer utilized qualitative secondary research and reviewed 15 relevant sources published between 2014 and 2024. Through this qualitative secondary research which is a form of library research, the notion of explicit reading and writing instructions is investigated. Furthermore, this paper explores strategies that can be employed in teaching source-based using explicit instruction in Indonesian tertiary-level EFL classrooms. The paper also highlights the challenges in implementing explicit instruction. This method of explicit reading and writing instructions should provide practical implications for teaching source-based writing. Keywords: academic writing; explicit instruction; source-based writing; paraphrasing; summarizing; synthesizing
INDONESIAN NON-ENGLISH MAJOR STUDENTS’ VIEWS AND EXPERIENCES: DUOLINGO FOR LEARNING ENGLISH
Authors: Zumrudiana Ainu , Syafitri Nurul Intan , Lestari Iin Widya , Zainuddin Moh
Published: February 2025

The research investigated non-English major students' views and perspectives on learning English through Duolingo. Qualitative methods were used, with 30 questionnaire items and 15 interview prompts to gather data on students' perception of using Duolingo to learn English, as well as the difficulties and obstacles they encountered. The participants were 41 undergraduate students in the sixth semester of the Early Childhood Education major at a university in Bojonegoro. This research focused on using Duolingo as a learning tool to enhance the teaching and learning process, considering the impact of technological advancements in education. The results showed that nearly 99% of participants viewed Duolingo as useful and functional. Challenges and obstacles in using the application for English learning were categorized into internal factors (mood, laziness, lack of knowledge, and time constraints) and external factors (network issues, smartphone usage, and application errors).Keywords: Duolingo application; learning English; English learning application; English learning media
Analisis Pengaruh Penggunaan Bahan Bakar B30 Terhadap Performance Deutz Bv 8m 628 Unit 5 Di PLTD Selayar
Authors: Herman Herman , Bestry Salempang Steven
Published: February 2025

Pembangkit Listrik Tenaga Diesel yang menggunakan sumber energi dari bahan bakar yang akan dikonversi menjadi energi mekanik lalu dikonversikan lagi menjadi energi listrik. Seiring perkembangan waktu perubahan jenis bahan bakar akan menunjang kebutuhan PLTD dalam menghasilkan listrik, dikarenakan bahan bakar fosil yang kian menipis, maka digunakan bahan bakar alternatif (biodiesel), tetapi dalam penggunaan bahan bakar tersebut terdapat beberapa pengaruh terhadap mesin. Sehubungan dengan itu penelitian ini bertujuan untuk mengetahui pengaruh dalam penggunaan bahan bakar B30 terhadap mesin diesel. Dalam penelitian ini, perbandingan pengaruh bahan bakar B30 dan HSD terhadap mesin Deutz BV 8M 628 di PLTD Selayar. Data yang digunakan diperoleh dari data sekunder dari PLTD Selayar. Data lainnya diperoleh dari spesifikasi bahan bakar yang telah dikeluarkan dari PT. Pertamina. Data-data tersebut diperoleh dengan studi literatur sebagai pengambilan data sekunder untuk analisis dan untuk melengkapi data didapat dari teknik wawancara dengan instansi PLTD Selayar. Bedasarkan hasil penelitian diketahui bahwa pengaruh dari penggunaan bahan bakar B30 mengalami kenaikan pada SFC maupun Efisiensi Thermal jika dibandingkan dengan HSD, selain itu terjadi peningkatan pemakaian filter bahan bakarpada saat penggunaan bahan bakar B30.
Dental Health Education Using PowerPoint Media to Improve Maternal Behavior in Maintaining Dental and Oral Hygiene of Students of GMIT Baumata Elementary School
Authors: Wali Agusthinus , Nubatonis Melkisedek O. , Krisyudhanti Emma , Variani Ratih
Published: February 2025

Dental health education is a planned and directed effort to create an environment that encourages individuals or community groups to change their old behaviors, which are less favorable for their dental health, to behaviors that are beneficial for their dental health. Behavior change can occur naturally, influenced by the environment, or intentionally and systematically through knowledge, attitudes, and skills. The aim of this study is to determine the effect of dental health education using PowerPoint media to improve the behavior of mothers in maintaining the dental and oral hygiene of GMIT Baumata Elementary School students. This type of research is a quasi-experimental design with a pre-test and post-test research design. The population of this study includes mothers and students of GMIT Elementary School, and the research sample is the total population of mothers and students in grades I-VI at GMIT Baumata Elementary School, Taebenu District, Kupang Regency, totaling 89 people. The instruments in this study were questionnaires and dental and oral hygiene examination forms. The results of the effectiveness test analysis showed that the behavior of mothers in maintaining dental and oral health (p=0.000) significantly improved, indicating an increase in the mothers' behavior in maintaining dental and oral health. Similarly, the dental and oral hygiene status of the students (p=0.000) improved, indicating an increase in the students' dental and oral hygiene status. Therefore, it can be concluded that PowerPoint media is effective in improving the behavior of mothers in maintaining their children's dental and oral hygiene and in enhancing the dental and oral hygiene status of GMIT Baumata Elementary School students in Taebenu District, Kupang Regency. It is recommended that further research be conducted to provide comparative data.
Earthquake loss modelling for Seismic risk Management
Authors: Alcaz Vasile  , Zaicenco Anton  , Isiciko Eugen
Published: February 2025

Methodology for earthquake loss assessment has been developed in order to control and reduce the seismic risk. The application evaluates damage to built facilities and casualties from scenario (or historical) earthquakes. The probability of damage suffered by the structures for a given level of seismic hazard is evaluated using response spectra or macroseismic intensity.
Utilisation of Industrial Waste Products as an Effective Method of Ecological Disaster Prevention
Authors: Burya A.I.  , Burmistr M.V.  , Cherkassova N.G.  , Zhukova A.V.
Published: February 2025

The possibility of using fibre production wastes as polymeric compositional materials (PCM) was studied with the purpose of minimising ecological risks through the rational utilisation of production wastes and the reduction of biologically irresolvable materials in the environment. The articles of PCM were tested and used in the friction units of metallurgical, chemical and mining equipment in the construction of the machines. These articles can be used instead of ferrous or non-ferrous metals and textolite. The use of PCM as a bearing shell for spindle support in pilger mills, hemispheres of half-couplings pilger mills, cartridges, rollers of piercing mills, seats of pipe-cutting machines, friction-bearings in the rollers of rollerbeds in ovens, conveyor rollers of etching sections in tin-zinc production, in the production of ammonia saltpetre in oven rollers of electric-insulation aggregate, supports of blocks of de-fatting units in tower ovens, cleaning blocks in foundries, rotor plates in rotation compressors, cartridges of rollers in mining conveyor belts, in pumps of acid transition, sweet water and sea water, press-on bushes and guide bushes, hydroplungers of water-pumps increased the service life of these units by 3–6 times.
The University Regional Research Consortium (Moldavia) for Environmental Monitoring and Protection – as a premise for the optimisation of living conditions through the prevention of natural and human ecological catastrophes
Authors: Toma Ovidiu
Published: February 2025

The flooding of the river Bistrita in the Moldavia region of Romania, resulted in an ecological catastrophe. One effect was to accumulate different waste products from all the villages in the area of the river – especially poliethylentereftalat (P.E.T.) bottles - and to deposit them in the Bicaz Lake. Now some parts of Bicaz Lake are partially covered with millions of PET bottles. Our Consortium was already involved in some ecologizations but our operations in this area have had to be extended due to the macrodimension of this damage.
Natural and man made disasters in the Moldova area of Romania
Authors: Douglas Brian  , Toma Ovidiu
Published: February 2025

We take a look at the causes and effects of both natural and man made disasters in recent times in the Moldova region of Romania. In this document we hope to highlight the lessons which can be learned to help avoid future disasters, both natural and of a man made nature.