bluuebunny/crossref_metadata_2025 huggingface dataset:
Hydrochemical Characteristics and Identification of Groundwater Pollution Sources in Tropical Savanna
Authors: Abdulsalam Abduljalal , Ramli Mohammad , Jamil Nor , Ashaari Zulfa , Umar Da’u
Published: March 2021

Groundwater pollution of the watershed is mainly influenced by the
multifaceted interactions of geogenic and anthropogenic processes. In
this study, classic chemical and multivariate statistical methods were
used to assess the groundwater quality and identify the potential
pollution sources affecting the groundwater quality of Galma
sub-watershed in a tropical savannah. For this purpose, the dataset of
18 groundwater quality variables covering 57 different sampling
boreholes (BH) was used. The order of abundance of the main cations and
anions in the samples are Ca2+ > Na+ > Mg2+
> K+ and HCO3− > Cl− > SO4−2
> NO3− respectively. Piper diagram classified the
groundwater types of the watershed into mixed Ca–Mg–Cl type of water,
which means no cations and anions exceeds 50%. The second dominant
water type was Ca–Cl. The Mg–HCO3 water type was found in BH 9, and
Na–Cl water type in BH 29 respectively. Hierarchical cluster analysis
grouped the sampling boreholes into five statistically significant
clusters based on similarities of groundwater quality characteristics.
Principal component extracted two principal components that explained
around 65% of the total variance, which natural and anthropogenic
processes especially agricultural activities as the dominant factors
affecting the groundwater quality. The findings of this study are useful
to the policy and decision-makers for formulating efficient groundwater
utilization and management plans for the groundwater resources.
Multi-omics profiling of a CHO cell culture system unravels the effect of culture pH on cell growth, antibody titer and product quality
Authors: Lee Alison , Kok Yee Jiun , Lakshmanan Meiyappan , Leong Dawn , Zheng Lu , Lim Hsueh Lee , Chen Shuwen , Mak Shi Ya , Ang Kok Siong , Templeton Neil , Salim Taha , Wei Xiaona , Gifford Eric , Tan Andy Hee-Meng , Bi Xuezhi , Ng Say Kong , Lee Dong-Yup , Ling Wai Lam , Ho Ying Swan
Published: March 2021

A robust monoclonal antibody (mAb) bioprocess requires physiological
parameters such as temperature, pH, or dissolved oxygen (DO) to be
well-controlled as even small variations in them could potentially
impact the final product quality. For instance, pH substantially affects
N-glycosylation, protein aggregation and charge variant profiles, as
well as mAb productivity. However, relatively less is known about how pH
jointly influences product quality and titer. In this study, we
investigated the effect of pH on culture performance, product titer and
quality profiles by applying longitudinal multi-omics profiling,
including transcriptomics, proteomics, metabolomics and glycomics, at
three different culture pH set points. The subsequent systematic
analysis of multi-omics data showed that pH set points differentially
regulated various intracellular pathways including intracellular
vesicular trafficking, cell cycle, and apoptosis, thereby resulting in
differences in specific productivity, product titer and quality
profiles. In addition, a time-dependent variation in mAb N-glycosylation
profiles, independent of pH was identified to be mainly due to the
accumulation of mAb proteins in the endoplasmic reticulum (ER) over
culture time, disrupting cellular homeostasis. Overall, this
multi-omics-based study provides an in-depth understanding of the
intracellular processes in mAb-producing CHO cell line under varied pH
conditions and could serve as a baseline for enabling the quality
optimization and control of mAb production.
Invited commentary for Modified Technique for Coarctation of the Aorta with hypoplastic distal aortic arch; a keystone shift away from the archway?
Authors: Stevens Randy , Throckmorton Amy , Mulinari Leonardo
Published: March 2021

Kozyrev et al. report their results in a modified technique for
coarctation of aorta with hypoplastic distal aortic arch (1). This paper
represents a quality initiative as much as a technical manuscript. The
authors included 32 patients during a three year time period from 2016
until 2019.
Accuracy of 1-Hour Plasma Glucose During the Oral Glucose Tolerance Test in Diagnosis of Type 2 Diabetes in Adults: A Meta-analysis
Authors: Ahuja Vasudha , Aronen Pasi , Kumar TA Pramod , Looker Helen , Chetrit Angela , Bloigu Aini H , Juutilainen Auni , Bianchi Cristina , Sala Lucia La , Anjana R M , Pradeepa R , Venkatesan U , Jebarani S , Baskar V , Fiorentino Teresa Vanessa , Timpel Patrick , DeFronzo Ralph A , Ceriello Antonio , Prato Stefano Del , Abdul-Ghani Muhammad , Keinänen-Kiukaanniemi Sirkka , Dankner Rachel , Bennett Peter H , Knowler William C , Schwarz Peter , Sesti Giorgio , Oka Rie , Mohan V , Groop Leif , Tuomilehto Jaakko , Ripatti Samuli , Bergman Michael , Tuomi Tiinamaija
Published: March 2021

Objective One-hour plasma glucose (1-h
PG) during the oral glucose tolerance test (OGTT) is an accurate predictor of type
2 diabetes. We performed a meta-analysis to determine the optimum cut-off of
1-h PG to detect type 2 diabetes using 2-h PG as the gold standard.

Research
Design and Methods We included 15 studies with 35,551 participants
from multiple ethnic groups (53.8% Caucasian) and 2705 newly detected cases of diabetes based on 2-h PG during OGTT. We
excluded cases identified only by elevated fasting plasma glucose and/or HbA1c.
We determined the optimal 1-h PG threshold and its accuracy at this cut-off to
detect diabetes (2-h PG ≥ 11.1
mmol/L) using a mixed linear effects regression model with different weights to
sensitivity/specificity (2/3, 1/2, and 1/3).

Results Three cut-offs of 1-h PG at 10.6 mmol/L, 11.6 mmol/L,
and 12.5 mmol/L had sensitivities of 0.95, 0.92, and 0.87 and specificities of 0.86,
0.91, and 0.94 at weights 2/3, 1/2, and 1/3, respectively. The cut-off of 11.6 mmol/L
(95% CI 10.6, 12.6) had a sensitivity 0.92 (0.87, 0.95), specificity of 0.91
(0.88, 0.93), AUC 0.939 (95% confidence region for sensitivity at a given specificity:
0.904, 0.946), and a positive predictive value of 45%.

Conclusions The 1-h PG of ≥ 11.6 mmol/L during OGTT has a good sensitivity and specificity for detecting type 2 diabetes. Prescreening with a
diabetes-specific risk calculator to identify high-risk individuals is
suggested to decrease the proportion of false-positive cases. Studies
including other ethnic groups and assessing complication risk are warranted.
Patent Madenciliği
Authors: KAYAKÖKÜ Ahmet , AKAY Diyar
Published: March 2021

Patent veri tabanları sürekli ve süratli bir şekilde büyüyen hacmiyle, günümüzün en önemli teknik bilgi kaynağı konumundadır. Oldukça geniş ve detaylı olan patent veri tabanlarından bilgi elde edebilmek için, gelişen veri analiz yöntemlerine başvurmak kaçınılmaz hale gelmiştir. Patent verisinden bilgi elde etmeyi ifade etmek üzere son zamanlarda patent madenciliği tabiri kullanılmaya başlanmıştır. Patent veri tabanlarının hem yapısal hem de yapısal olmayan karakteri sebebiyle, patent madenciliğinde veri madenciliği tekniklerine de metin madenciliği tekniklerine de ihtiyaç duyulmaktadır. Ancak patent dokümanları buluşların teknik yönlerinin açıklandığı metinlerden oluştuğundan, metin madenciliği uygulamalarının bu alandaki işlevi daha fazladır. Bu çalışmada patent dokümanlarının özelliklerinden bahsedilerek, metin madenciliği ile elde edilebilecek sonuçlara değinilmiştir. Literatürde patent metinleri üzerinde kullanılan metin madenciliği yöntemlerinden örnekler verilmiş ve gelecekte yapılacak çalışmalara yön vermek açısından patent dokümanları arasında benzerlik tespitinin neden önemli olduğu açıklanmıştır.
PENGARUH KEBIJAKAN DIVIDEN, LIKUIDITAS, TANGIBILITY, ASSET TURNOVER, DAN COMPANY GROWTH TERHADAP STRUKTUR MODAL
Authors: Ratuloly Mirnawati , Wijayanti Anita , Siddi Purnama
Published: March 2021

Capital structure is the ratio between debt (foreign capital) and own capital (equity). There are several factors that affect capital structure such as dividend policy, liquidity, tangibility, asset turnover and company growth. This study aims to determine the effect of dividend policy, liquidity, tangibility, asset turnover and company growth on capital structure. In this study, the sampling method was carried out using purposive sampling and obtained as many as 14 companies in the consumer goods industry sector which were listed on the Indonesia Stock Exchange during 2015-2018. Thus the amount of data observed in this study amounted to 56 data. Data in this study were analyzed using Statistical Package for Social Sciences (SPSS) 22 with multiple linear regression analysis methods. The results of this study indicate that liquidity and asset turnover affect the capital structure while the dividend policy, tangibility and company growth do not affect the capital structure.
MUDANÇAS NO CLIMA E A DISTRIBUIÇÃO POTENCIAL FUTURA DE Mimosa scabrella BENTH
Authors: Da Silva Mariéle Alves Ferrer , Higuchi Pedro , Da Silva Ana Carolina
Published: March 2021

Objetivou-se predizer como a distribuição potencial de Mimosa scabrella Benth. será impactada por mudanças no clima. Para as coordenadas geográficas da espécie, foram consideradas 19 variáveis bioclimáticas e a altitude. O nicho bioclimático foi modelado por intermédio do algoritmo de Máxima Entropia (Maxent). A qualidade dos ajustes foi verificada por meio dos valores de TSS. Foram realizadas projeções para o ano de 2070, utilizando-se o consenso dos ajustes com TSS > 0,85, considerando um cenário otimista (RCP4.5) e um pessimista (RCP8.5), conforme o quinto relatório do IPCC.  M. scabrella apresenta distribuição fitogeográfica de caráter subtropical, sendo influenciada principalmente pela quantidade de chuva no verão e isotermalidade. Nos cenários mais e menos otimistas estima-se que haverá uma redução de, respectivamente, 21,7 e 48,9% em sua área de ocorrência potencial. Em se tratando de áreas estratégicas para a conservação da espécie, se destacaram as áreas planálticas e serranas na região Sul e Sudeste.
دور الإدارة التشاركية في فاعلية القرارات الادارية
Authors: Rahman Nihayat S. , Hussein Razaw A. , Wali Ahlam I.
Published: March 2021

هدف البحث الى تعرف على دور الادارة التشاركية بابعادها الفرعية المتمثلة ب ( بناء فريق العمل ، تفويض  السلطة ، تعزيز العلاقات الانسانية ) في فاعلية قرارات الادارية .قدم البحث اطاراَ نظرياً مفاهيمياً للمتغيرات الرئيسية والفرعية جرى اختيار شركة كورك تيلكوم مجالاً لاجراء الجانب اليداني للبحث ، تنبع اهمية البحث من اهمية المواضيع المبحوثة .انتهد البحث منهجياً وصفياً تحليلاً ، وحددت محموعة من الفريضات كإجابات تخمينية عن مشكلة البحث والتي جرى اختبارها بأدوات احصائية متعددة ، من خلال استخدام برنامج الاحصائي SPSS-V.22.واستخدمت الاستبانة كوسيلة للحصول على البيانات، حيث تم توزيعها على عينة من مديري الاقسام والشعب في الشركة وبلغ عددهم (55  ) استمارة ، وتم استرجاع (51 ) استمارة استبانة وكانت جميعها صالحة للتحليل. استنتج البحث وجود علاقة  وتاثير لكافة ابعاد الادارة التشاركية في فاعلية القرارات الادارية واوصى البحث بتوظيف هذه العلاقة لخدمة الشركة المبحوثة والاستمرار في المحافظة على المستويات العالية لكل من ابعاد الادارة التشاركية ومؤشرات القرارات الادارية .
The Effect of pH on the Corrosion Rate of 316L Stainless Steel, Nitinol, and Titanium-6%Aluminium-4%Vanadium in Hank’s Solution
Authors: Nik Masdek Nik Rozlin , Wahab Nor’Aini , Ahmad Nawawi Natasha , Tajudin Aznul
Published: March 2021

Nowadays, the application of 316L Stainless Steel, Nitinol and Ti-6Al-4V alloys as biomaterials have become popular due to their implant performance and durability. In this research work, the effect of pH on the corrosion rate of 316L Stainless Steel, Nitinol and Ti-6Al-4V alloys have been investigated. An electrochemical method was applied in order to investigate the corrosion behaviour of these biomaterials under simulated biological condition. The potentiodynamic polarization were performed in a Hank’s solution at pH value 7.4 (neutral) and 5.2 (acidic). SEM, XRD, microhardness and surface roughness were also carried out to characterise the corroded surface. The potentiodynamic polarization results showed that both Ti-6Al-4V and 316L stainless steel had high corrosion rate at pH 5.2 (acidic) as compared to pH 7.4 (neutral). The corrosion rate for Ti-6Al-4V alloys at pH 7.4 was 22.80×10-3 mmpy before it increased to 23.65×10-3 mmpy at pH 5.2. Similar behaviour was observed for 316L stainless steel where at pH 7.4 and increase the corrosion rate increasing from 2.387×10-3 mmpy at pH 7.4 to 5.325×10-3 mmpy at pH 5.2. However different corrosion behaviour was observed for Nitinol as the corrosion rate decreasing from 17.65×10-3 mmpy to 16.04×10-3 mmpy at pH 7.4 and 5.2, respectively. Hence, the decrease of pH value was found to not cause any significant effect on the corrosion resistance of Nitinol as compared to 316L SS and Ti-6Al-4V alloys.
Semantic Complex of Travel in Work of A. G. Bitov
Authors: Mohammed Adam E. A. , Kovalenko A. G.
Published: March 2021

The semantic complex of travel in the work of Andrey Bitov is analyzed. It has been proven that the range of the writer’s travelers is very wide; they correlate with each other. The authors state that, in a broad sense, A. Bitov’s literary travels add up to an extensive travel catalogue, which presents all kinds of embodiment of artistic space and time. In addition, the writer’s work is viewed as the embodiment of the vector of movement in the “space of freedom”, as the space of “longing for culture.” Particular attention is paid to a cycle of stories about the Soviet republics, where important tools for the writer to create the image of the Empire — the reflective and questioning author (Socratic dialogue) were found. The question about the popsition of exclusion (M. Bakhtin) and defamiliarisation (V. Shklovsky) is raised. The novelty of the study is seen in the fact that travel stories have become at the same time a defamiliarized narrative about Russia. The conclusion is made that the semantic complex of travel in the work of A. Bitov connects the geographical (physical) and spiritual (metaphysical) spaces, that is, the external objective world and the internal spiritual and intellectual space.
Military-Historical Anthropology: Vectors of Theoretical Polemic in Russian and English Historiography
Authors: Nikolae F. V. , Sofronova L. V. , Khazina A. V.
Published: March 2021

A classification of theoretical approaches in military-historical anthropology is proposed. The authors note that social constructivism prevails in English-language historiography as a whole, while in Russian studies an existential approach does. It is shown that the socio-cultural direction and the phenomenology of the front-line experience have recently begun to play an increasing role. It is concluded that a theoretical analysis of the differences between these approaches allows not only to identify their strengths and problematic sides, but also to outline the prospects for interaction between them. The authors note that the most promising today is the setting for the participation of representatives of the academic community in joint cultural practices of representing the front-line experience with combatants, which makes it possible to make the dialogue between the phenomenology of front-line experience and the socio-cultural approach the most productive. It is argued that within the framework of such a dialogue, the question of the relationship between normative social structures and local practices should not be reduced to a previously known answer. It is emphasized that it makes sense not to level out or radically absolutize the theoretical tension between the indicated approaches, but to work it out — to look for points of practical interaction and modification of existing strategies for comprehending the past.
Marginalities of the Handwritten Qurans of Highland Dagestan as a Historical Source
Authors: Osmanova M. N.
Published: March 2021

The article is devoted to the study of the content of extra-textual records — marginals — in the margins of handwritten Qurans, recorded by Dagestan oriental scholars at different times while working with written monuments in private and mosque book collections of highland Dagestan. It was established that most of the discovered marginals were made in Arabic, however, since the beginning of the 18th century, such records were often kept in local languages using Arabic script. It is shown that the Quran, due to its sacred functions, became a repository of the most important documents of various nature. It is reported that extra-textual recordings are extremely diverse in their content, they affect many aspects of the socio-political, spiritual, economic and cultural life of the region. The experience of studying marginals over the past several decades is summarized. The author of the article draws attention to the newest findings of the Qurans made by archaeographic expeditions in 2017—2019 in private book collections in the Shamil region of the Republic of Dagestan. It is emphasized that an analysis of their thematic composition and a scientific description of the manuscripts stored in them will give an idea of some aspects of the social, cultural and religious life of the peoples of Dagestan.
Fishing of Tatars of the Irtysh Forest-Steppe Region in the 19th — Early 21st Centuries
Authors: Tikhomirova M. N. , Tikhomirov K. N.
Published: March 2021

The issues of fishing among the West Siberian Tatars living on the territory of the Omsk region in the forest-steppe zone on the left bank of the Irtysh River are considered. The authors dwell on the characteristics of the traditional aquatic areas of the XIX — early XXI century, fishing objects, tools and methods of fishing. It is proved that the fishing of the Tatars in these settlements was an auxiliary branch of the economy in the past and present. It was shown that they fished almost all year round, mainly on lakes, where the main object of fishing was crucian carp. It is concluded that fishing was more developed among residents of settlements in the area of the village of Yalankul. It is shown that the Tatars of the villages in the area of the Ulenkul village are now less engaged in it because of the drying up of water bodies, as well as because of the withdrawal of lakes from nature management for transfer to the hunting farm and the reserve. The novelty of the research is seen in filling the gaps in the study of this topic. The authors note that material was collected about the fishing of the population, which previously consisted mainly of Siberian Bukharians and was actually assimilated by the Tatars.
Characteristics of the Tapanuli Orangutan Habitat in the Conflict Area of Batang Toru Landscape, North Sumatra, Indonesia
Authors: Kuswanda Wanda , Harahap R. Hamdani , Alikodra Hadi S. , Sibarani Robert
Published: March 2021

Forest fragmentation has resulted in decreased wildlife habitat, which has triggered conflicts with humans due to the use of the same plants. This has been particularly contentious with the tapanuli orangutan. Research of the tapanuli orangutan (Pongo tapanuliensis) habitat is very limited. The aims of this research is to examine the latest habitat conditions, such as land cover, composition of vegetation, feed plant, and habitat carrying capacity to provide recommendations for habitat management in developing a mitigation policy of the human-tapanuli orangutan conflict. The research location is focused on the area of human-orangutan conflict in the Batang Toru Landscape in South Tapanuli Regency, which took place from August to December 2019. Vegetation analysis was conducted using the strip transect method with a total of 294 plots (11.76 ha). The number of species at the pole and tree levels were high with 149 species (46 families) and diversity index (H') > 3. Eighty feed plant species were found and expected to support the growth of the orangutan population of 247 individuals. The density and diversity of cultivated plant species in the buffer zone were high and consumption by orangutans resulted in human-tapanuli orangutan conflict, especially on durian (Durio zibethinus Murray). Conflict with humans will cause stress and disruption to the growth of the tapanuli orangutan. We recommend habitat management to mitigate conflict through patrols for monitoring habitat destruction in conservation forests, enrichment of feed plants in Forest Management Units, cultivation of orangutan non-food crops on community lands, and building a corridor with orangutan food crops with fruits that are not utilized by humans.
Hubungan Tingkat Pengetahuan dengan Sikap Terhadap Infeksi Menular Seksual pada Mahasiswa Pendidikan Dokter
Authors: Saenong Rizqa Haerani , Sari Linda Puspita
Published: March 2021

Latar Belakang: Infeksi Menular Seksual (IMS) merupakan suatu penyakit yang dapat ditularkan melalui hubungan seksual. IMS akan lebih berisiko apabila melakukan hubungan seksual dengan berganti-ganti pasangan baik melalui vagina, oral maupun anal. Menurut BKKBN tahun 2017, sebanyak 14% wanita dan 2% pria kawin yang sudah pernah melakukan hubungan seksual mengalami IMS atau gejalanya dalam waktu 12 bulan terakhir. Tujuan: untuk mengetahui tingkat pengetahuan dan sikap Mahasiswa Program Studi Pendidikan Dokter Universitas Muhammadiyah Jakarta Angkatan 2019 tentang Infeksi Menular Seksual. Metode: penelitian ini merupakan penelitian survei yang bersifat analisis deskriptif. Pendekatan yang digunakan pada penelitian ini adalah cross sectional, dengan jumlah sampel 105 responden. Instrumen penelitian berupa angket dengan menggunakan skala guttman, pemberian skor 2 apabila pertanyaan dijawab benar dan 1 apabila dijawab salah. Analisis uji hipotesis menggunakan uji Chi Square. Hasil: terdapat 91,4% responden yang memiliki pengetahuan dengan kategori baik dan 90,5% responden memiliki sikap dengan kategori baik terhadap Infeksi Menular Seksual. Responden yang memiliki pengetahuan tentang Infeksi Menular Seksual yang baik cenderung memiliki sikap yang baik pula terhadap Infeksi Menular Seksual, dengan nilai p value 0,000 maka dapat dikatakan bahwa terdapat hubungan yang signifikan antara pengetahuan tentang infeksi menular seksual dengan sikap terhadap infeksi menular seksual. Kesimpulan: seseorang yang memiliki pengetahuan Infeksi Menular Seksual yang baik mempengaruhi sikap terhadap Infeksi Menular Seksual yang baik sebesar ±22 kali lebih besar dibanding yang tidak memiliki pengetahuan mengenai Infeksi Menular Seksual.
Proses Gatekeeping Portal Media Daring (Studi Kasus pada Media Daring Okezone.com)
Authors: Irene Irene , Rusdi Farid
Published: March 2021

Peoples in the world are in needs of information. Verified information is producted through an long journalistic process. The selecting process of information to get in the media editorial is called gatekeeping. In this era of great technology, medias with network based or online that can be reached by internet connection are taking the hype. The gatekeeping process of every media, especially online media is influenced by various kinds of internal dan external factors. This causes the exact point of journalistic content that produced can be modified. The purpose of this research is to know how the gatekeeping process in an online media is being held. This research is using two models of gatekeepings and hiearchy influence theory to explain whole process of gatekeepings in online media. Case study method is used in this research. The results showed both of the gatekeepings model are applied in the Okezone.com’s gatekeeping process. Internal and external factors are also actively influence the gatekeeping process.Informasi merupakan kebutuhan setiap masyarakat di dunia. Informasi yang terverifikasi telah melalui sebuah proses jurnalistik yang panjang. Proses penyeleksian informasi untuk masuk dalam redaksional media disebut gatekeeping. Saat ini marak media dalam jaringan atau online yang dapat dijangkau setiap masyarakat dengan koneksi internet. Proses gatekeeping setiap media, khususnya media daring dipengaruhi oleh berbagai faktor internal dan eksternal organisasi media. Hal ini memungkinkan adanya pergeseran makna dalam setiap konten jurnalistik yang dihasilkan. Penelitian ini dilakukan dengan tujuan untuk mengetahui bagaimana proses gatekeeping dalam sebuah media daring berjalan. Peneliti menggunakan dua model gatekeeping dan teori hirarki pengaruh untuk menjelaskan keseluruhan proses gatekeeping yang berlangsung dalam media daring. Studi kasus peneliti lakukan pada media daring milik MNC Group yaitu Okezone.com. Hasil penelitian ditemukan bahwa kedua model gatekeeping yang digunakan oleh peneliti diterapkan dalam proses gatekeeping Okezone.com. Dalam proses gatekeeping Okezone.com juga menunjukkan adanya faktor internal dan eksternal media yang secara aktif mempengaruhi proses redaksional.
Pola Komunikasi Suami Istri Berbeda Agama dalam Membangun Keharmonisan
Authors: Tan Herlita , Tamburian Daniel
Published: March 2021

Communication is one of crutial aspect in human life. When done right, communication certainly make relationship grows better and in harmony. In many occation, miscommunication happen when there is a failure in delivering messages to the interlocutor. Hence, the miscommunication could cause problem to married couple. Successful marriage is created when husband and wife could communicate well while holding on their religius value. Nonetheless, there always families which is not living in harmony. Therefore, the purpose of this thesis is to analyse marriage couple communication pattern, especially in different religion to create a happy family. This study uses qualitative approaches with descriptive research method. Researches interviewed 6 resource which consist of a married husband and have a different religious but still harmonized. The result of this study showed that husband and wife who had lived up many years and there is an attitude that relented and understanding of each other, as well as a variety way to maintain it.Komunikasi merupakan salah satu aspek penting dalam kehidupan manusia. Komunikasi yang benar tentunya dapat membuat hubungan menjadi lebih baik dan harmonis. Sebaliknya kesalahpahaman dalam komunikasi bisa menimbulkan masalah yang serius. Seringkali dalam proses komunikasi terdapat kegagalan dalam penyampaian pesan kepada lawan bicaranya. Hal ini dapat menimbulkan permasalahan khususnya bagi pasangan suami istri yang sudah menikah. Keharmonisan suami istri terjadi hanya jika mereka dapat berkomunikasi dengan baik dan tetap berpegang teguh kepada nilai-nilai agama yang dianut. Namun tidak dapat dipungkiri bahwa di dalam tatanan rumah tangga menjadi tidak harmonis yaitu salah satunya adalah perbedaan agama pada suami istri. Maka dari itu penelitian ini ingin mengetahui pola komunikasi suami istri berbeda agama dalam membangun keharmonisan. Penelitian ini menggunakan pendekatan penelitian kualitatif dengan metode deskriptif. Pada penelitian ini peneliti mewawancarai enam narasumber yang terdiri dari pasangan suami istri yang sudah menikah dan memiliki perbedaan agama namun masih tetap harmonis. Hasil penelitian lewat kajian pola komunikasi suami istri ini memperlihatkan bahwa pasangan suami istri yang telah menjalani kehidupan rumah tangganya bertahun- tahun terdapat sikap saling mengalah dan pengertian antara satu sama lain, serta memiliki cara-cara yang beragam untuk tetap mempertahankannya.
Makna Ritual Perayaan Mapag Sri bagi Warga Desa Segeran Kidul Indramayu
Authors: Lifiani Ega Rifa , Sukendro Gregorius Genep
Published: March 2021

Segeran Kidul is a village in Indaramayu area, West Java Province. Segeran Kidul  Villagers are mostly working  as a farmers. Segeran Kidul Village has traditional rituals related to farmers, it is called “Mapag Sri”, Mapag means welcoming and Sri is the goddess of rice, Mapag Sri is a sacred activity for local community, this activity is carried out to welcome the arrival of the big harvest. The purpose of this research is to find out more about the meaning in the Mapag Sri ritual which is carried out once a year. The meaning contained in the Mapag Sri ritual is the gratitude of villagers of Segeran Kidul Village to God Almighty who gives bountiful harvests. The ritual is usually performed using an offering or “sesajen” as well as the Mapag Sri ritual which uses sesajen and tumpeng rice. The symbol attached to the Mapag Sri ritual is sharing activities for  people in need and always be grateful to God by giving the bountiful harvest result. This   research uses the symbolic interaction theory popularized by George Herbert Mead. This theory explains how the meaning that comes from the human mind about oneself at a social level which aims to interpret it in society.Desa Segeran Kidul merupakan desa yang berada di Daerah Indaramayu Provinsi Jawa Barat, Desa Segeran Kidul memiliki mayoritas masyarakatnya sebagai petani. Desa Segeran Kidul memiliki ritual adat yang berkaitan dengan petani yaitu ritual Mapag Sri, Mapag berarti menyambut dan Sri adalah dewi padi, Mapag Sri adalah ucapara adat atau kegiatan sakral bagi masyarakat setempat, kegiatan ini dilaksanakan untuk menyambut datangnya panen raya. Tujuan dari penelitian ini adalah untuk mengetahui lebih jauh lagi makna yang ada didalam ritual Mapag Sri yang dilakukan satu tahun sekali. Makna yang terdapat didalam ritual Mapag Sri adalah rasa syukur masyarakat Desa Segeran Kidul kepada Tuhan Yang Maha Esa yang memberikan hasil panen yang melimpah. Ritual biasanya dilakukan dengan menggunakan sebuah sesajen sama halnya dengan ritual Mapag Sri yang menggunakan sesajen dan juga nasi tumpeng. simbol yang melekat pada ritual Mapag sri yaitu melakukan kegiatan saling berbagi kepada orang yang membutuhkan dan selalu berterima kasih kepada Tuhan dengan memberikan hasil yang diingkan. Penelitian menggunakan teori interaksi simbolik yang dipopulerkan oleh George Herbert Mead. Teori ini menjelaskan bagaimana makna yang berasal dari pikiran manusia mengenai diri sendiri yang tengah berinteraksi sosial yang bertujuan untuk menginterpretasikan ditengah masyarakat.
Makna Kesinambungan Kampanye Green Beauty oleh Kosmetik Garnier
Authors: Lesilolo Neldy Maria , Marta Rustono Farady , Rewindinar Rewindinar
Published: March 2021

The Garnier green beauty campaign conveys a message to the public through advertising media. The message is conveyed to the public regarding environmental activities that have a sustainable meaning. The green beauty campaign through advertising media shows Garnier's environmental friendly actions. Cause consumer behavior that turns into a form of responsible attitude. The purpose of this study was to determine the meaning of the sustainability of the green beauty campaign through Garnier's cosmetic advertising media. Researchers used a qualitative approach with Ferdinand de Saussure's semiotic analysis method which was signifier and signified. Methods of data collection with the method of documentation. The object of research was through the green beauty campaign advertisement and the subject of Garnier. The one-minute green beauty campaign ad is divided into seven scenes. The results of this study found the meaning of sustainability, by taking real action to become green beauty. Being green beauty is explained through verbal and non-verbal signs. Marked by each scene of the Garnier green beauty campaign advertisement, the meaning of sustainability is found. The real action starts from the production process to processing Garnier cosmetic waste.Kampanye Garnier green beauty menyampaikan pesan kepada masyarakat melalui media iklan. Pesan yang disampaikan kepada khalayak mengenai kegiatan peduli lingkungan yang memiliki makna berkesinambungan. Kampanye green beauty melalui media iklan menunjukan aksi nyata Garnier yang ramah lingkungan. Menyebabkan perilaku konsumen yang berubah menjadi wujud sikap yang bertanggung jawab. Tujuan penelitian ini untuk mengetahui makna kesinambungan dari kampanye green beauty melalui media iklan kosmetik Garnier. Peneliti menggunakan pendekatan kualitatif dengan metode analisis semiotika Ferdinand de Saussure secara signifier dan signified. Metode pengumpulan data dengan metode dokumentasi. Objek penelitian melalui iklan kampanye green beauty dan subjek Garnier. Iklan kampanye green beauty yang berdurasi satu menit dibagi menjadi tujuh scene. Hasil Penelitian ini menemukan makna kesinambungan, dengan melakukan aksi nyata menjadi green beauty. Menjadi green beauty dijelaskan melalui tanda secara verbal dan non verbal. Ditandai melalui setiap scene iklan kampanye Garnier green beauty memiliki makna kesinambungan yang ditemukan. Aksi nyata dimulai dari proses produksi sampai pengolahan limbah kosmetik Garnier.
Pengaruh Influencer terhadap Minat Beli Produk Fashion Wanita pada Instagram
Authors: Stevani Natasia , Junaidi Ahmad
Published: March 2021

This research has a purpose to determine the relation and how much influence between Elika Natania influencers on buying interest in women's fashion products on Instagram. The sample in this study was 100 Elika Natania’s followers on her Instagram account. Respondents were using a purposive sampling technique. This research provides results that there is a strong relationship between the two variables and there is a big influence between the two variables reaching 67.8%. So, the conclution is that the influencer variable significantly influences the buying interest variable.Penelitian ini memiliki tujuan untuk mengetahui hubungan dan seberapa besar pengaruh antara influencer Elika Natania terhadap minat beli produk fashion wanita pada media sosial Instagram. Sampel pada penelitian ini adalah followersinfluencer Elika Natania pada akun media sosial Instagram sebanyak 100 Responden menggunakan teknik purposive sampling. Penelitian ini memberikan hasil bahwa ada hubungan yang kuat antara kedua variabel dan terdapat pengaruh yang besar antara kedua variable mencapai 67,8%. Keismpulannya adalah variabel influencer secara signifikan berpengaruh terhadap variabel minat beli.
Interaksi Simbolik dalam Word of Mouth Untuk Mengenalkan Iphone di Kalangan Persahabatan (Studi Etnografi Teori Peran Pengambilan Keputusan dalam Lingkungan Persahabatan)
Authors: Christofer Daniel , Pribadi Muhammad Adi
Published: March 2021

The purpose of introducing the Iphone to friends in an environment of friendship is to influence an environment so that there is a common use of the product. The Iphone itself is one of the best mobile phones in its class compared to other competitors. Iphone users who are satisfied will be a promotional medium with word of mouth theory and will try to influence the environment so that they are like themselves. Consumers who have positive feedback according to role theory will act as initiators and influencers who will try to incorporate thoughts as Iphone users into their environment. The initiator himself tries to do one of the symbolic interaction theories, namely the pygmalion effect where a thinker turns into a reality. This research was conducted with the aim to find out how much the role of social interaction that occurs in an environment can influence the purchase decision of a product or service. This research is different from previous studies because on this occasion symbolic interactions were examined through word of mouth.Tujuan mengenalkan Iphone kepada para sahabat dalam lingkungan persahabatan adalah untuk memengaruhi sebuah lingkungan agar terjadi kesamaan penggunaan produk. Iphone sendiri merupakan salah satu handphone terbaik di kelasnya dibanding kompetitor lainnya. Para pengguna Iphone yang merasa puas akan menjadi media promosi dengan teori word of mouth, dan akan mencoba untuk memengaruhi lingkunga nya agar seperti dirinya. Konsumen yang memiliki feedback positif menurut teori peran akan bertindak sebagai initiator dan juga influencer yang akan mencoba memasukkan pemikiran sebagai pengguna Iphone ke dalam lingkungannya. Initiator sendiri mencoba melakukan salah satu teori interaksi simbolik yaitu pygmalion effect dimana sebuah pemikirin berubah menjadi sebuah kenyataan. Penelitian ini dilakukan dengan tujuan mengetahui peran interaksi sosial yang terjadi di sebuah lingkungan dalam memengaruhi keputusan pembelian sebuah produk maupun jasa. Penelitian kali ini berbeda dari penelitian terdahulu karena pada kesempatan kali ini interaksi simbolik yang dikaji melalui word of mouth.
Historical aspects of etiopathogenesis and treatment of syphilitic infection in Russia (report I)
Authors: Chebotarev Vyacheslav V. , Zemtsov Mikhail A. , Odinets Aleksei V. , Chebotareva Natalia V.
Published: March 2021

In the historical aspect, experimental studies conducted by domestic and foreign researchers on the study of T. pallidum are presented. The incubation period and its progress through the lymphatic and circulatory pathways are established. We studied the clinical manifestations of syphilis in monkeys and rabbits corresponding to the stage manifestation in a patient with syphilis. The nature of immunity, concepts of super-and reinfection, hidden forms of syphilis, generalization of infection with damage to the nervous, cardiovascular system and visceral organs. Drugs for the treatment of patients with syphilis in the pre-penicillin period are highlighted.
Genotoxicidade das nanoestruturas aplicadas em saúde: uma revisão integrativa
Authors: Brito Josimar Elpídio de , Paranhos Caroline Nogueira , Viana Deuzuita dos Santos Freitas , Nunes Joedson Lima , Cavalli Luiz Claudio Garabeli
Published: March 2021

Objetivo: A respectiva revisão tem como objetivo analisar a genotoxicidade das nanoestruturas aplicadas em saúde, visto que, embora esses materiais sejam amplamente utilizados em escalas industriais e comerciais no ramo medicinal, os potenciais riscos à saúde associados à exposição a eles, ainda precisam ser compreendidos. Métodos: A metodologia utilizada trata-se de uma revisão de literatura com abordagem descritiva e informativa nos quais os processos de delineamento se deram pela busca na literatura científica publicada nos últimos cinco anos nas bases de dados PubMed, LILACS e SciELO, por meio dos descritores (genotoxicity AND nanostructures AND health) e aplicação de quatro filtros de seleção. Resultados: As análises mostraram que direta ou indiretamente a maioria dos materiais abordados nos estudos apresentou efeito genotóxico em maior ou menor intensidade correlacionados às características ou as concentrações utilizadas. Considerações finais: Realização de estudos de genotoxicidade dos nanomateriais para identificar seu dano potencial é imensamente importante. No entanto, os estudos revisados sobre a genotoxicidade de nanomateriais não apresentam uma homogeneidade significativa. Com isso, gera uma insegurança sobre a diversidade de testes para se chegar às conclusões aceitáveis.
Selective Crystallization via Vibrational Strong Coupling
Authors: Hirai Kenji , Ishikawa Hiroto , Chervy Thibault , HUTCHISON JAMES , Uji-i Hiroshi
Published: March 2021

The coupling of (photo)chemical processes to optical cavity vacuum fields is an emerging method for modulating molecular and material properties. Recent reports have shown that strong coupling of the vibrational modes of solvents to cavity vacuum fields can influence the chemical reaction kinetics of dissolved solutes. This suggests that vibrational strong coupling might also effect other important solution-based processes, such as crystallization from solution. Here we test this hither-to unexplored notion, investigating pseudopolymorphism in the crystallization from water of ZIF metal-organic frameworks inside optical microcavities. We find that ZIF-8 crystals are selectively obtained from solution inside optical microcavities, where the OH stretching vibration of water is strongly coupled to cavity vacuum fields, whereas mixtures of ZIF-8 and ZIF-L are obtained otherwise. This work suggests that cavity vacuum fields might become a tool for materials synthesis, biasing molecular self-assembly and driving macroscopic material outcomes.
Enhanced Sampling of Chemical Space for High Throughput Screening Applications using Machine Learning
Authors: Mehta Sarvesh , Laghuvarapu Siddhartha , Pathak Yashaswi , Sethi Aaftaab , Alvala Mallika , Priyakumar U. Deva
Published: March 2021

In drug discovery applications, high throughput virtual screening exercises are routinely performed to determine an initial set of candidate molecules referred to as "hits". In such an experiment, each molecule from large small-molecule drug library is evaluated for physical property such as the binding affinity (docking score) against a target receptor. In real-life drug discovery experiments, the drug libraries are extremely large but still a minor representation of the essentially infinite chemical space , and evaluation of physical property for each molecule in the library is not computationally feasible. In the current study, a novel machine learning framework "MEMES" based on Bayesian optimization is proposed for efficient sampling of chemical space. The proposed framework is demonstrated to identify 90% of top-1000 molecules from a molecular library of size about 100 million, while calculating the docking score only for about 6% of the complete library. We believe that such a framework would tremendously help to reduce the computational hour and resources in not only drug-discovery but also areas that require such high-throughput experiments.
Analysis of the surgical treatment results for an acute cholecystitis in the senile and elderly patients, depending on term of the operative intervention performance
Authors: Zavgorodniy S. M. , Danylyuk M. B. , Rylov A. І. , Kubrak M. A. , Yareshko N. O. , Shchurov M. F.
Published: March 2021

Objective. To estimate the results of surgical treatment in the senile and elderly patients for an acute cholecystitis on background of biliary calculous disease in urgent abdominal surgery, depending on term of performance of operative intervention.

Materials and methods. In the investigation there were included 89 patients, ageing 60-89 yrs old with diagnosis: an acute cholecystitis on background of biliary calculous disease. Median age of the patients have constituted (69.66 ± 7.30) yrs old.

Results. All the patients were operated in urgent order, average duration of preoperative period was 20.00 (7.00; 27.00) h. Laparoscopic cholecystectomy with abdominal drainage was performed in 70 (78.7%) patients; laparotomy, cholecystectomy with abdominal drainage- in 14 (15.7%); laparotomy, cholecystectomy with drainage of common biliary duct - in 5 (5.6%). In 3 (4.3%) patients while performing of laparoscopic cholecystectomy the necessity have emerged for conversion due to hemorrhage from the gallbladder bed. Preoperative preparation in the senile and elderly patients during more than 24 h have led to significant improvement of their general state, comparing with those, who were operated in terms up to 24 h from the moment of admittance to hospital (U-criterion = 749.50; p = 0.0286). As well, in accordance to data, concerning postoperative period analysis, there was noted significant improvement of the patients’ state, preoperative preparation of whom lasted more than 24 h, comparing with the patients, preoperative preparation of whom lasted lesser than 24 h (U-criterion = 491.00; p < 0.0001). Average duration of stationary stay have differed in this two Groups (U-criterion = 919.00; p = 0.3984).

Conclusion. The surgery deferred performance for an acute cholecystitis in the senile and elderly patients permits to improve the results of postoperative treatment and to reduce the frequency of postoperative complications significantly.
Some aspects of surgical treatment of erysipelas
Authors: Vasylevska L. A. , Shapoval S. D.
Published: March 2021

Objective. To study the incidence and to determine the main trends of treatment of the erysipelas surgical forms.

Materials and methods. There were retrospectively and prospectively analyzed 114 histories of the patients’ cases, who were treated in stationary in the centre of purulent-septic surgery of the Municipal Hospital No 3 of Zaporizhzhya in 2019 - 2020 yrs.

Results. Mostly often the affection site was localized on the lower extremities. In bullous and phlegmonous forms of erysipelas the most frequent clinical signs of intoxication were general weakness, hyperthermia, muscular pain. In necrotic form of erysipelas the signs of severe intoxication with nausea, regurgitation and confusion were observed. In complex treatment of erysipelas the main principles are antibioticotherapy and early surgical processing of the pathological process zone. Determination of indices of the procalcitonin content in the blood serum gives possibility to estimate progression and generalization of the process and constitutes a sensitive test for efficacy of the treatment conducted.

Conclusion. Radical surgical intervention and timely targeted antibioticotherapy constitutes basic elements of successful treatment for surgical forms of erysipelas, and this position must not be revised. Procalcitonin content in the blood serum constitutes a diagnostic marker, permitting to prognosticate the sepsis development timely.
Diagnosis and treatment of the neck paragangliomas
Authors: Belotserkovskyi V. , Bondar A. V. , Yanieva D. G.
Published: March 2021

Diagnosis and treatment of the neck paragangliomas
As Representações de Stephen Hawking em Filmes Biográficos
Authors: Fernandes João , Lima Guilherme , Aguiar Jr. Orlando Gomes
Published: March 2021

Este artigo tem como objetivo analisar dois filmes biográficos de Stephen Hawking com o intuito de identificar as representações do cientista presentes em obras cinematográficas. Para isso, a investigação contou com a análise fílmica e os filmes foram categorizados seguindo as principais representações identificadas pela literatura. A análise identificou as representações mais comuns presentes nas cenas e sequências em que o protagonista atuou, levando em consideração o contexto de determinadas ações do cientista. A representação de gênio foi a mais evidente nos dois filmes. Os resultados indicaram que as obras analisadas, de gênero biográfico, também estão fadadas a permear estereótipos que contribuem com uma visão deturpada do cientista e do labor científico, assim como acontece em outros gêneros cinematográficos.
Improvement of Flexural and Shear Strength of RC Beam Reinforced by Glass Fiber-Reinforced Polyurea (GFRPU)
Authors: Song Jun-Hyeok , Eun Hee-Chang
Published: March 2021

The Glass Fiber-Reinforced Polyurea (GFRPU) which is the composite by the elastic polyurea and milled glass fiber have the mechanical characteristics to enhance tensile strength as well as ductility. It must be reinforcement materials in repair and retrofit applications for strengthening structural capacity and has a merit of simple construction of spray coating to prevent the debonding from concrete surfaces unlike the existing strengthening methods such as Fiber-reinforced polymer (FRP) or steel plate. This work compares the improvement degree in load-carrying capacity as well as flexural ductility of RC beam reinforced externally by polyurea or GFRPU. Seven specimens of four reinforced concrete (RC) beams for evaluating flexure-resisting capacity and three beams for shear-strengthening capacity are tested. The mechanical behavior and characteristics of the specimens reinforced by local and global reinforcement method classified according to strengthened area are compared. It is shown that the polyurea- or GFRPU- reinforcement leads to the enhancement in the load-resisting capacity up to 8~11% and flexural ductility within the range of 8.41~13.9 times of the non-reinforced beam. And the global reinforcement method has more improvement in the shear- and flexure-resisting capacity than the local method. It is also observed that the GFRPU can be more effectively utilized in enhancing the structural shear-resisting capacity than the flexure-carrying capacity. Doi: 10.28991/cej-2021-03091662 Full Text: PDF