bluuebunny/crossref_metadata_2025 huggingface dataset:
Subclasses of Bi-Univalent Functions Associated with q-Confluent Hypergeometric Distribution Based Upon the Horadam Polynomials
Authors: EL-DEEB Sheza , EL-MATARY Bassant
Published: January 2021

In this paper, we introduce new subclasses of analytic and bi-univalent functions connected with a q-confluent hypergeometric distribution by using the Horadam polynomials which, these polynomials, the families of orthogonal polynomials and other special polynomials, as well as their extensions and generalizations, are potentially important in a variety of disciplines in many branches of science, especially in the mathematical, statistical and physical sciences. For more information associated with these polynomials . Furthermore, we find estimates on the first two Taylor-Maclaurin coefficients |a₂| and |a₃| for functions in these subclasses and obtain Fekete-Szegő problem for these subclasses.
Pencarian Informasi Dakwah Islam melalui Media Online Pada Masa Pandemi COVID-19 bagi Komunitas Muslim
Authors: Prasanti Ditha , Karimah Kismiyati El
Published: January 2021

Masa pandemi COVID-19 menjadikan individu memanfaatkan media sosial untuk mencari informasi terbaru, namun banyak informasi yang diperoleh tentang COVID-19 yang meresahkan. Tujuan penelitian ini untuk 1) mengetahui alasan pencarian informasi dakwah islami melalui media online pada masa pandemi COVID-19, 2) mengungkapkan dampak masa pandemi COVID-19 bagi pencarian informasi dakwah islami bagi komunitas remaja muslim X, 3) mengetahui proses pencarian informasi dakwah islam yang dilakukan komunitas remaja muslim X melalui media online. Metode penelitian yang digunakan adalah studi kasus COVID-19, dengan teknik pengumpulan data berupa studi literatur, observasi, dan wawancara mendalam dengan komunitas remaja muslim di Bandung. Hasil penelitian yang dilakukan menunjukkan bahwa: 1) alasan pencarian informasi dakwah islam berawal dari adanya  kebanjiran informasi tentang pandemi COVID-19 sehingga mendorong komunitas tersebut untuk mencari solusinya, 2) dampak masa pandemi COVID-19 menyebabkan komunitas remaja muslim aktif dan selektif dalam pencarian informasi dakwah islam melalui media online, 3) proses pencarian informasi dakwah islam tersebut mulai dari mengelompokkan kebutuhan, membuat jadwal dan kelompok diskusi online, menggunakan wadah atau platform diskusi online seperti Google Meet, Zoom Meeting, dan WA Video Call. Masa pandemi COVID-19 telah mendorong komunitas tersebut tetap aktif dalam pencarian informasi dakwah Islam. Substansi penelitian ini memberikan kontribusi berupa rekomendasi kebijakan baru para remaja dalam mencari informasi melalui media online harus selektif agar tidak merugikan lainnya.
Saliva pH Changes in Patients with High and Low Caries Risk After Consuming Organic (Sucrose) and Non-Organic (Maltitol) Sugar
Authors: W Widowati , SH Akbar , MH Tin
Published: January 2021

Introduction: Enamel demineralization is associated with decrease in saliva pH due to fermentation of sugar by oral commensal. Thus, exploring the changing pattern of saliva pH is meaningful in dental caries prevention. The aim of this study was to compare the changing pattern of saliva pH after consuming different types of sweeteners (sucrose and maltitol). Methods: It was a case-control study involving 14 male patients attending IIUM dental clinic who were selected with the intention of getting seven patients with high caries risk ( DMFT ≥6) and seven patients with low caries risk (DMFT ≤3) with initial saliva pH interval of 6.5 to7.5. Patients were asked to consume snacks containing 8 gram sucrose and 8 gram maltitol as sweeteners. The changing pH values of the saliva were measured by Waterproof pHTestr 10BNC (Oakton, Vernon Hills, USA) seven times consecutively at 0 (before snack consumption), and at 5, 10, 15, 20, 30 and 60 minutes after snack consumption. The pH values of saliva of patients with low and high caries risk after consuming sucrose and maltitol were statistically analized by using Anova and Tukey-HSD tests at α = 0.05. Result: There were significant differences in saliva pH changes between low-risk group and high-risk group after consuming sucrose and maltitol. Conclusion: The changing patterns of saliva pH in high-risk patients were lower than those of low-risk patients after consuming two types of snacks containing sucrose and maltitol.
Surgical Management of Paediatric Neglected Humeral Supracondylar Fracture: A Series of 3 Cases in 3 Years
Authors: Yi Kow Ren , Leng Low Chooi , Kamaludin Nur Azuatul Akmal , Abdul Aziz Aziah , Mohd Daud Kamariah Nor
Published: January 2021

Introduction: Supracondylar fracture of the humerus is common among paediatric population. In our country, it is not uncommon for patients to present late to the hospital after an injury. Devnani reported a case series of 28 children who sustained supracondylar humerus fracture and presented late (mean 5.6 days) to the hospital. We report our experience in managing 3 patients who presented late (range 15 days to 8 months) with neglected supracondylar humerus fracture in 3 years. Case report: Case 1: A right hand-dominant 5-year-old boy sustained a fall 8 months prior to presentation to the hospital. He was treated with traditional methods immediately after the injury. He presented with malunion of left humeral supracondylar fracture with varus deformity and limited left elbow range of movements. An open reduction (lateral approach) and corrective osteotomy were performed and 2 lateral K-wires were inserted. Case 2: A 10-year-old boy with right hand dominance sustained a closed left supracondylar humerus fracture Gartland 3 after a fall. His parents initially refused any surgical intervention. However, they finally agreed for surgery on day 15 post-trauma. An open reduction (posterior approach) and callus removal were done and 2 crossed K-wires were inserted. Case 3: A right hand-dominant 5year-old girl had history of fall 1 month prior to presentation to the hospital. She was treated with traditional methods initially. She presented with malunion of the left supracondylar humerus fracture with limited range of motion of her left elbow. An open reduction (posterior approach) and corrective osteotomy were performed and 2 crossed K-wires were inserted. Discusssion: Two patients underwent open reduction via the posterior approach and 1 patient via the lateral approach. Only one patient required callus removal while 2 patients required osteoclasis. All patients recovered without complication and there was improved range of movement of the elbows. Conclusion: Surgical intervention is the treatment of choice in managing neglected supracondylar humerus fracture.
Knowledge, Attitude and Practice Towards Road Traffic Regulations Among University Students, Malaysia
Authors: AA Redhwan , AJ Karim
Published: January 2021

Introduction: Each year, more than 20 million people are injured and 1.17 million are killed due to road traffic accidents. Developing countries account for over 85% of the deaths, and close to 90% of the disability caused by road traffic crashes worldwide. The objectives of this study were to determine the knowledge, attitudes and practice and the factors influencing university students in Malaysia concerning road traffic accident. Materials and Methods: This study was conducted among the students of Management and Science University, Malaysia. The questionnaire was distributed randomly to the students of the Faculty of Health and Life Sciences. Data was analyzed using SPSS version 13, T-test and ANOVA. Results: The total number of 109 students with the mean age of 20.94±1.89 years participated in this study. Approximately 39 (35.7%) of the participant had been involved in one or more than one road traffic accident. About 93.6% of them were very strongly/strongly convinced of seat belts importance. Multivariate analysis using the multiple linear regression method showed that age and attitude were significantly associated with the exposure to the accident. Conclusion: The study participants had moderate knowledge about road traffic regulations and most of them mentioned that high speed, drivers’ lack of awareness about traffic regulation and laws, and drivers’ non-compliance with traffic rules and regulation were the most important cause of road traffic accidents. Almost all students were very strongly/strongly convinced of seatbelts importance. Age and attitude were significantly associated with the exposure to the accident.
Фальшивомонетничество в Центральной и Восточной Европе в эпоху Средневековья и раннего Нового времени
Authors: Myzgin Cyril
Published: January 2021

Рецензія: Бойко-Гагарин А.С. Фальшивомонетничество в Центральной и Восточной Европе в эпоху Средневековья и раннего Нового времени. Киев: «Украинская конфедерация журналистов, 2017, 549 с., с илл.
A WELCOME BREAKTHROUGH OR A CONNECTOR OF THE (IN)COMPATIBLE: LANGUAGE CORPORA AS A SEGMENT IN ENGLISH LEXICOLOGY CLASSES
Authors: Babić Željka
Published: January 2021

The necessity of studying the use of language corpora in foreign language teaching at the university level as a possible connector with contemporary scientific and research trends is intensified by the very need to bring the universities in the Republic of Srpska and Bosnia and Herzegovina closer to the regional and European scientific and research networks as well as to profile them within the aforementioned academic space. Efforts to set the corpus linguistic theoretical and practical posits as the basis of contemporary
interdisciplinary linguistic research in the educational practices are aimed at emphasising the need to redesign some of the courses in the foreign language departments where students and teachers have expressed a desire and an interest in learning about this approach to the applied linguistic practice. The paper presents the results of a project aimed at familiarising students with the corpus studies and
fundamentals of corpus linguistics, as well as with working independently on the selected corpora with the goal to achieve learning outcomes that could not have been previously included in teaching in the first cycle of academic studies. The paper primarily focuses on the challenges and experience gained through the introduction of the corpus studies within the English lexicology classes. Challenges faced by the teacher during the presentation of the corpus linguistic analysis, students’ disinterestedness for the linguistic theoretical and practical research, the lack of literature and practical tools, as well as the limited time and content action framework, have been overcome nevertheless, which is evident from the students’ positive feedback. The most valuable result is the actual raising awareness of students as far as the importance of their role as active participants in the realisation of teaching process outcomes is concerned - the process which is expected to possess not only an
educational function but also to create a practitioner who will be able to respond to the challenges of the contemporary job market.
GERAKAN FEMINISME RADIKAL OPMT DALAM ISU KEKERASAN SEKSUAL DI TIMOR TIMUR TAHUN 1974-1999
Authors: Djara Kristian Thomas
Published: January 2021

ABSTRAKKekerasan seksual terhadap perempuan di Timor Timur pada masa konflik (1974-1999) seringkali ditinjau menggunakan berbagai pendekatan yang tidak mampu menjelaskan relasi kuasa antara laki-laki dan perempuan. Tujuan utama penelitian ini adalah mengoperasionalisasikan konsep-konsep feminisme radikal dalam gerakan OPMT. Metode yang digunakan adalah metode kualitatif pada studi kasus kekerasan seksual terhadap perempuan di Timor Timur pada masa konflik (1974-1999). Gerakan feminissme radikal OPMT tidak hanya memperjuangkan kebebasan perempuan dari belenggu kekerasan seksual militer Indonesia melainkan juga belenggu tradisi komunitas lokal yang merugikan perempuan. Hasil penelitian merujuk pada kekuatan militer dan komunitas lokal Timor Timur sehingga peran OPMT perlahan meredup dan terlupakan dalam dominasi kelompok perjuangan maskulin di Timor Timur.Kata Kunci: Kekerasan Seksual, OPMT, Timor Timur, Feminisme Radikal
TRAINING KETERAMPILAN SOSIAL PADA PEMBELAJARAN IPS BERFOKUS EFIKASI DIRI SISWA
Authors: Dr. Tetep , Suherman Ade
Published: January 2021

Model training keterampilan sosial dapat meningkatkan efikasi diri siswa di SMP Negeri 1, SMP Negeri 2 dan SMP Negeri 3 Ciamis. Model training yang digunakan melalui; (a) sistem modelling, dilakukan dengan cara memperlihatkan contoh tentang ketrampilan berperilaku yang spesifik, (b) bermain peran, dilakukan dengan cara mendengarkan petunjuk yang disajikan model atau melalui video, (c) umpan balik terhadap kinerja yang tepat, yang dilakukan dengan cara memberi pengukuh terhadap peserta yang menunjukkan kinerja yang tepat. Setelah dilakukannya model training ini dapat  1)meningkatnya kecakapan dalam keterampilan sosial; 2) siswa aktif bertanya kepada guru ketika ada mata pelajaran yang tidak dimengerti, memahami dan mengatur emosi diri maupun orang lain (kontrol emosi), 3) siswa merespon orang lain dan mengarahkan tindakan sosial (sikap sosial),  4) interaksi dan berkomunikasi siswa secara verbal maupun non verbal (komunikasi) dengan individu dan kelompok lainnya sehingga membentuk siswa menjadi trampil berinteraksi dengan orang-orang di sekitarnya, baik dalam hubungan formal maupun informal, 5) siswa bertanggung jawab atas tindakan (tanggung jawab) dan, 6) siswa lebih memperhatikan orang lain (peduli). Kata kunci: Training Keterampilan Sosial, Pembelajaran IPS, Efikasi Diri
Long-term Condition Management for Prisoners: exploring prevalence and compliance with national monitoring processes
Authors: Wright Nat , Allgar Victoria , Hankins Frances , Hearty Philippa
Published: January 2021

Abstract 

BACKGROUND: Long-term conditions (LTCs) are a significant cause of morbidity and mortality and prisoner populations have a disproportionately high prevalence of risk factors for LTCs. The size and mean age of the prison population has increased rapidly in recent years. The UK Quality Outcomes Framework (QOF) is a national standardised framework embedded in community general practice with financial remuneration linked to assessment and ongoing review of key clinical outcomes pertaining to LTCs. However, healthcare in prisons in England is not linked to financial remuneration through the QOF framework and prison clinicians are not mandated to adhere to the framework. 

AIM: To explore prevalence of LTCs in remand prisons and measure compliance with QOF monitoring. 

DESIGN AND SETTING: Quantitative analysis of secondary data on SystmOne.  

METHODS: Secondary data analysis of data extracted from the prison primary care record pertaining to patient self-report of LTC, level of confirmation by supporting evidence and compliance with QOF monitoring frameworks.   

RESULTS:  17% of the sample had at least one LTC, the most common condition being asthma, confirmed in 12% of the sample. Having an LTC was associated with female gender and increasing age. Prevalence rates for the other LTCs were hypertension 3%, epilepsy was 3%, coronary heart disease 2%, diabetes 2% and chronic obstructive pulmonary disease 1%. Just 34% of the eligible sample had had a QOF template completed. Higher rates of completion were associated with younger age and there were also statistically significant inter-prison differences.  

CONCLUSION: There is a pressing need to embed standardised QOF monitoring systems within an integrated community/prison commissioning framework supported by connectivity between prison and community primary care records of not just the summary care record but also all activity related to QOF compliance.
Rawi Khawarij dalam Sahih Al-Bukhari
Authors: Nur Shiddiq Muhammad
Published: January 2021

Tulisan ini mendiskusikan beberapa riwayat hadis di dalam Sahih al-Bukhari yang di dalam sanadnya terindikasi terdapat rawi ahli bid’ah yaitu Khawarij. Di antara rawi Khawarij yang terdapat di dalam Sahih al-Bukhari bernama ‘Imran ibn Hittan. Dengan menggunakan studi pustaka, tulisan ini menemukan informasi bahwa terdapat perbedaan pendapat di kalangan para ahli hadis mengenai penerimaan terhadap riwayat yang berasal dari seorang rawi ahli bid’ah. Ulama yang menolak riwayat ahli bid’ah mendasarkan pendapatnya pada anggapan bahwa mereka adalah orang-orang yang kufur. Sedangkan ulama yang membolehkan riwayat ahli bid’ah umumnya memiliki syarat yang jelas. Syarat tersebut ialah bahwa rawi ini tidak termasuk ke dalam rawi yang muttaham bi al-kizb, dan juga riwayatnya tidak menyeru pada bid’ahnya. Temuan dari tulisan ini adalah bahwa rawi yang bernama ‘Imran ibn Hittan, meskipun merupakan seorang Khawarij, ia adalah seorang yang tsiqah. Di dalam riwayatnya yang terdapat di dalam Sahih al-Bukhari tidak menyeru pada bid’ah yang diyakininya. Sehingga hadis yang diriwayatkan melalui jalur ‘Imran ibn Hittan ini tidak perlu diragukan lagi keshahihannya.
医院管理中的药剂科药事管理分析
Authors: 生 琳 , 张 长坡
Published: January 2021

目的：药剂科药事管理在医院管理中的应用效果。方法：在2019年1月至2020年1月时间段实施药事管理,并以2017年12月至2018年12月时间段未实施药物管理作为对照,对药物管理的应用情况进行了解。结果：管理前后不良事件发生对比差异有统计学意义,P
Pengaruh Penghindaran Pajak dan Ukuran Perusahaan Terhadap Struktur Modal Perusahaan Properti & Real Estate Tahun 2018-2019
Authors: Sihotang Rani , Simbolon Maropen , Hutabarat Francis
Published: January 2021

Tujuan penelitian ini adalah untuk memahami pengaruh penghindaran pajak dan ukuran perusahaan terhadap struktur modal perusahaan property dan Real Estate tahun 2018-2019. Penelitian ini menggunakan analisis data deskriptif yang nantinya akan dikelola dengan menggunakan perangkat lunak SPSS.65 perusahaan Property & Real Estate yang terdaftar di BEI untuk tahun 2018-2019 menjadi sampel dalam penelitian ini. Variable terikat dalam penelitian ini adalah  penghindaran pajak dan ukuran perusahaan sebagai variabel mediasi dengan menggunakan struktur modal sebagai variabel bebas.dalam penelitian ini. Penelitian ini menggunakan descriptif statistic uji F dan uji T sebagai analisis statistik. Hasil analisis yang dilakukan pada penelitian ini menunjukkan bahwa penghindaran pajak tidak memiliki pengaruh yang signifikan terhadap struktur modal,ukuran perusahaan memiliki pengaruh yang signifikan terhadap struktur modal dan penghindaran pajak berpengaruh signifikan terhadap struktur modal dengan ukuran perusahaan sebagai mediasi
Diagnóstico del manejo de aceites usados en el municipio de Pasto, departamento de Nariño
Authors: Pérez Galided Álvaro José
Published: January 2021

Los aceites lubricantes usados son provenientes de la refinación fracciona del petróleo, en su vida útil tienen muchos usos y el principal es el de lubricantes del sector automotor, una vez termina su ciclo de vida este hidrocarburo se convierte en un desecho difícil de deshacer y con un alto grado de contaminación ya que en su composición final este aceite tiene partículas de plomo, cadmio, arsénico, cloro etc que son químicos altamente contaminantes para nuestro medio ambiente y fuentes hídricas, estudio demuestran que cuando este aceite es quemado libera más plomo a la atmosfera q cualquier otra fuente de contaminación y cuando este es arrojado a fuentes hídricas un solo litro puede contaminar mil litros de agua haciendo de esta que no se pueda beber.En la ciudad de San Juan de Pasto no existe una entidad encargada de recopilar este aceite usado al cual se puede periódicamente almacenarlo, hacerle un tratamiento, filtrarlo y de reincorporación al mercado, al no haber un sistema de que se encargue de todo esto, se vuelve un desecho difícil de deshacer para todas las servitecas facilitando el comercio ilegal de este hidrocarburo para la combustión en distintas actividades ya que es muy económico, pero dañino para la salud y el medio ambiente.
Propuesta de habitáculos semilla de interés social para la sierra centro del Ecuador
Authors: Guerrero Campaña Iván Fernando , Díaz Pérez Yosmel
Published: January 2021

En el Ecuador, específicamente en la sierra centro andina, la demanda de espacios físicos sostenibles es evidente, y lo corroboran los datos del Instituto Nacional de Estadísticas y Censos (INEC) y el Ministerio de Desarrollo Urbano y de Vivienda, en lo sucesivo MIDUVI, que identifica a grupos de personas de pobreza moderada y extrema, habitando en espacios informales y hacinados, donde se generan necesidades en su diario vivir, relacionadas directamente con su espacio físico. Este trabajo fue desarrollado mediante una investigación de enfoque mixto, donde se empleó una recopilación de datos tipo documental, una entrevista no estructurada a especialistas del MIDUVI y la observación de campo, donde se identificó y registró en fichas de observación, los patrones de idiosincrasia, mediante la actuación en el diario vivir de las personas en estudio y sus diferentes dinámicas. El proyecto fue desarrollado para el diseño de hábitat asequible y sostenible, generando prototipos de habitáculo semilla, que responden a tres zonas climáticas en la sierra centro del Ecuador, y a formas de habitar de este territorio, con un acceso de 6000 dólares, hasta el valor de 12500 dólares, según los registros del MIDUVI a grupos subvencionados totalmente.
Acceso al conocimiento mediante dispositivos móviles por estudiantes universitarios
Authors: Montúfar Flores Manuel Alfredo , Rosero Ortega Viviana Estefanía , Tulcán Guamán Jenniffer Jacqueline , Veloz Piarpuezan Maryory Lisbeth
Published: January 2021

El objetivo de la presente investigación fue analizar el acceso al conocimiento mediante dispositivos móviles por estudiantes universitarios. La metodología de investigación científica usada para el caso Universidad Politécnica Estatal del Carchi fue la Bibliográfica, Descriptiva y De campo, que mediante la técnica de la encuesta logró recolectar datos que permitieron conocer cuál es la incidencia que genera el uso de las Tecnologías de Información y Comunicación (TIC) en la práctica de la educación universitaria digital. Desde el ámbito académico y del Observatorio Binacional de Frontera se concluye que el acceso al recurso móvil posibilita la transferencia de conocimiento, el aprendizaje virtual y el éxito profesional; no obstante, es necesario motivar el deseo de aprendizaje en los estudiantes, ya que el uso adecuado de los equipos móviles facilita el proceso de formación académica, ahorra tiempo y optimiza los recursos digitales en favor del alumnado.
O fetichismo da mercadoria na sociedade de obsolescência programada
Authors: Araújo Gizelda Rodrigues de , Marques Edmilson
Published: January 2021

O referido trabalho faz uma abordagem sobre o fetichismo da mercadoria de Marx, trazendo à tona alguns exemplos que remetem ao valor de uso e valor de troca e faz uma reflexão ao advento da obsolescência programada enfocando a volatilidade com que o fascínio da mercadoria desapareça e pontuar que o padrão de consumo transformou-se numa forma de afirmação social e consequentemente o consumismo representa um pilar importante para o capitalismo. Para tanto objetiva entender sobre o fetichismo da mercadoria em consonância com a obsolescência programada da sociedade atual. Trata-se de uma pesquisa bibliográfica de cunho exploratório e para tanto contou-se com a contribuição dos estudos de Marx em seu livro O Capital, especificamente na parte que trata sobre a Mercadoria, Bauman. No livro Modernidade Líquida, onde aborda sobre a fluidez dos objetos e do descarte da mercadoria e Netto que ressalta sobre trabalho, sociedade e valor.
Maderas nativas: Alternativa sostenible para fabricar cordófonos en Panamá
Authors: Collantes Ruben Darío , Caballero M. Héctor , Jerkovic Maricsa , Caballero M. Héctor Roberto
Published: January 2021

Los instrumentos musicales de cuerda o cordófonos, están construidos generalmente por maderas como aliso, arce, caoba, tilo, palo de rosa, entre otras; de las cuales existe una creciente demanda y algunas ya se encuentran en estado vulnerable o amenazado. En Panamá, se cuenta con maderas nativas de excelente calidad, empleadas por artesanos, denominados lutieres, que poseen destrezas y habilidades para fabricar instrumentos musicales. El objetivo de este trabajo fue conocer las especies de maderas nativas de Panamá, que pueden ser utilizadas para la fabricación de instrumentos de cuerda, como alternativa sostenible a las maderas importadas. Para ello, se escogió Tabebuia rosea (roble de sabana) y Peltogyne purpurea (nazareno) para confeccionar el cuerpo de una guitarra eléctrica semi hueca; mientras que, para confeccionar una guitarra eléctrica de cuerpo sólido, se optó por Cedrela tonduzii (cedro granadino) para cuerpo y mástil, Mangifera indica (mango) para el tope del cuerpo y Dalbergia retusa (cocobolo) para el diapasón, tapas de electrónica y alma. Los componentes tanto de electrónica como herrajes, son de marcas reconocidas por su calidad. Para el acabado, en la guitarra de cuerpo semi hueco, se aplicó laca transparente, aprovechando la coloración natural del nazareno; mientras que, para la de cuerpo sólido, el tope de mango fue teñido con un degradado de verde a violeta y el clavijero con la parte frontal en negro. Los resultados obtenidos fueron, en ambos casos, guitarras de excelente calidad sonora y presentación, pudiendo estar a la altura de instrumentos de gama alta, ofrecidos por grandes marcas. El uso de maderas nativas, representa un ahorro en materiales, aprovechamiento sostenible de recursos y contribuye con el desarrollo de la artesanía nacional, con mercado potencial para músicos y conocedores.
Control Biológico de Phthorimaea operculella (Zeller, 1873) y Tecia solanivora (Povolny, 1973) (Lepidoptera: Gelechiidae) mediante Bacillus thuringiensis var. Kurstaki en papa almacenada en Cerro Punta, Chiriquí, Panamá
Authors: Pittí Araúz Manuel Isaac , Collantes Ruben Darío , Delgado Luis Carlos
Published: January 2021

El objetivo del trabajo fue evaluar Bacillus thuringiensis var. Kurstaki (Bt-K), como alternativa de control biológico de polillas de papa Phthorimaea operculella y Tecia solanivora, en almacenamiento en Cerro Punta, Chiriquí, República de Panamá. Para ello, se seleccionaron cinco lotes de papa, sometidos a diferentes dosis de aplicación del producto Dipel 6.4WG (Bt-K). Se empleó un Diseño de Bloques Completos al Azar, con cinco tratamientos y cuatro repeticiones. También se realizó un análisis de regresión, en función de la dosis del producto y el porcentaje de daño final. Los lotes se mantuvieron almacenados durante 100 días, a temperatura y humedad controladas. Los tratamientos consistieron en dosis de Dipel 6.4WG de 50 g hasta 90 g, fraccionados de tres hasta cinco aplicaciones. Como resultados, no se encontraron diferencias significativas entre los tratamientos, manteniéndose el daño por debajo del umbral permisible. El análisis de regresión permitió estimar que, sin tratamiento, el daño final en los tubérculos hubiese sido de 9.36% (R2 = 0.95), lo cual supera el umbral de daño permisible de 7%. Se concluye que, la dosis de 50 g del producto Dipel 6.4WG fraccionado en tres aplicaciones, es suficiente para mantener los daños por polilla de papa en almacenamiento, por debajo del umbral permisible. Se recomienda repetir la experiencia con concentraciones menores de producto e incluir un testigo absoluto. También debe evaluarse el uso de Bt-K, en bodegas empleadas por productores.
Evaluación del rendimiento de maíz amiláceo (Zea mays L.) bajo condiciones de riego por goteo y la fertilización nitrogenada
Authors: Acevedo Cruz Adan
Published: January 2021

El maíz es un cereal de elevado potencial en producción de grano y es altamente sensible al déficit hídrico y al nitrógeno; estos dos factores son las principales limitantes de los productores maiceros de la Comunidad deVista Alegre en SanMarcos-Ancash. En ese sentido, el objetivo de esta investigación fue evaluar el rendimiento de maíz amiláceo en condiciones de riego y secano con dos niveles de nitrógeno. Para ello, el estudio se planteó en Diseño de Bloques Completos al Azar (DBCA) con un arreglo factorial de 2x2 en 3 repeticiones. El riego se aplicó durante el Periodo Crítico (PC) entre dos semanas antes y después de la floración; y las dosis de 150 y 300 kg/ha de N en el estado fenológico de V3 y V6. Obteniendo el mejor rendimiento de 6,036 tn/ha de maíz amiláceo con el riego y la dosis de 300 kg/ha de N, seguido de 4,397 tn/ha con la misma dosis en secano. Con la fertilización de 150 kg/ha de N los rendimientos de 3,285 y 2,975 tn/ha en las modalidades de riego y secano no expresaron diferencia significativa según la prueba de Tukey. El CV residual fue de 5,228 % y el R2 de 97 %. Por tanto, la interacción entre el riego en el PC y la fertilización fraccionada de 300 kg/ha de N en las etapas V3 y V6 incrementa el rendimiento de maíz amiláceo.
Deciding a Bitstring of 1s is Non-Random is Impossible in General
Authors: Holloway Eric
Published: January 2021

Without domain knowledge, an algorithm given an extremely long sequence of 1s would be unsure whether the sequence is completely random.  When asked to predict the next digit, the algorithm can only give an equal weighting to 0 and 1.
Molecular Pattern of Anti-malarial Drug Resistance of Plasmodium falciparum in Bangladeshi Troops Working in Endemic Areas of Bangladesh and Africa
Authors: Amin Md Nurul , Yasmin Mahmuda , Akhtar Marufa Zerin , Ahsan Chowdhury Rafiqul
Published: January 2021

Members of Bangladesh Armed Forces work in two different malaria endemic area, Chittagong Hill Tracts (CHT) in Bangladesh and Sub-Saharan countries in Africa. This under-recognized group remained unexplored for long in respect to drug resistant falciparum malaria they usually suffer from. In this study, a total of 252 ‘dried blood samples on filter paper’ were collected between November 2014 and February 2016, from Plasmodium falciparum positive Bangladeshi troops working in Chittagong Hill Tracts (CHT), Bangladesh and five Sub Saharan African Countries namely, Central African Republic (CAR), Democratic Republic of Congo (DRC), Liberia, Mali and Ivory Coast. After DNA extraction from all these samples (94 from Bangladesh and 138 from African countries), plasmodium species was confirmed by a nested PCR following standard protocol with minor modifications. Thereafter, a multiplex nested PCR followed by restriction fragment length polymorphism (RFLP) method was employed to investigate the presence of chloroquine resistance marker ‘K76T mutation’ in P. falciparum chloroquine resistance transporters (pfcrt) gene and lumifantrine and mefloquine resistance marker ‘N86Y mutation’ in P. falciparum multidrug resistance1 (pfmdr1) gene. The P. falciparum DNA was confirmed in 35 (37.23%) Bangladeshi and 45 (28.48%) African samples. The ‘pfcrt (K76T) mutation’ that confers resistance to chloroquine, was detected in 93.10% Bangladeshi and 29.27% African samples. The ‘pfmdr1 (N86Y) mutation’ that confers resistance to lumifantrine and mefloquine, was detected in 20.69% Bangladeshi and only 2.44% African samples. The higher prevalence of chloroquine resistance of P. falciparum in Bangladesh than in African countries revealed that possible withdrawal of chloroquine from endemic areas and also periodic molecular survey to monitor pf resistance to chloroquine, mefloquine, lumefantrine and artemisinin among these troops working in both endemic areas.

Bangladesh J Microbiol, Volume 37 Number 1 June 2020, pp 1-6
Identification of Locally Isolated Cellulolytic Stenotrophomonas maltophilia from Rice Straw and Optimization of its Cellulase Activity
Authors: Sadida Faozia Faleha , Kamal Fatima Binte , Manchur Mohammed Abul
Published: January 2021

A highly cellulolytic bacterium was locally isolated from rice straw and identified as Stenotrophomonas maltophilia. Identification of the isolate based on the morphological, cultural and biochemical characteristics was confirmed with 16S rDNA analysis. The bacterium showed the highest level of reducing sugar and extracellular protein production when incubated for 3 days (348.75 μg/ml and 288.5 μg/ml respectively) at 40°C temperature (463.0 μg/ ml and 333.0 μg/ml respectively) and pH 6.5 (360.0 μg/ml and 349.0 μg/ml respectively) in Winstead’s broth having 1.5% CMC and 0.2% Yeast Extract as carbon and nitrogen source respectively. Crude cellulase enzymes produced by the bacterium showed the highest CMCase activity rather than FPase, Avicelase and ²-Glucosidase activities. Cellulase activity of the crude enzyme was also determined using the same parameters. The crude cellulase enzyme showed the highest CMCase activity when incubated for 60 minutes (232.5 U/ml), at pH 6.5 (105.0 U/ml), 35°C temperature (69.75 U/ml) using CMC and Peptone as carbon and nitrogen source respectively. Crude cellulase showed the highest activity in presence of mercury and SDS as metal and detergent respectively. Substrate specificity and SDS-PAGE analysis reveals that the cellulase may be an endo-1,4-glucanase.

Bangladesh J Microbiol, Volume 37 Number 1 June 2020, pp 15-22
Hepatitis E virus genotype 1f outbreak in Bangladesh, 2018
Authors: Baki AA , Haque Warda , Giti Susane , Khan AA , Rahman MM , Jubaida Nishat , Rahman Mustafizur
Published: January 2021

Hepatitis E virus (HEV) infection is a significant public health issue in many developing countries, causing waterborne outbreaks as well as sporadic hepatitis. We report here an outbreak of HEV genotype 1f infection during Apr-May 2018 among persons living at Halisohor, a low land of southern part of Chottogram District of Bangladesh. A total of 933 patients were admitted in Combined Military Hospital (CMH) Chottogram with symptoms of acute hepatitis. Among them 550 patients were tested by ELISA for HEV specific IgM and all were positive. Genotyping, sequencing and phylogenetic analysis based on ORF 2 region revealed that the outbreak was caused by genotype 1f and the strains were closely related to the previously reported HEV strains that caused outbreak in Bangladesh in 2010. The current outbreak was most likely linked with water supply as fecal contamination in water was evident and could be prevented by ensuring access to safe drinking water.

Bangladesh J Microbiol, Volume 37 Number 1 June 2020, pp 35-37
Identifikasi Penyebab Kerusakan Biologis Gambar Cadas Gua Prasejarah Maros, Sulawesi Selatan
Authors: Habibi Moh , Oetari Ariyanti , Eka Permana R. Cecep
Published: January 2021

Penelitian ini bertujuan untuk mengidentifikasi mikroorganisme (kapang dan bakteri) yang terdapat pada gambar cadas dan berpotensi sebagai biodeteriogen gambar cadas. Metode penelitian meliputi pengambilan sampel dan identifikasi molekuler. Identifikasi molekuler mengunakan primer 9F (5’-GAG TTT GAT CIT IGC TCAG-3’) dan 1510R (5’-GGT TAC CTT GTT ACG ACTT-3’) untuk bakteri, ITS1F (5’-CTT GGT CAT TTA GAG GAA GTAA-3’) dan ITS4R (5’-TCC TCC GCT TAT TGA TAT GC-3’) untuk kapang.  Siklus PCR yang digunakan pada penelitian ini sebanyak 35 siklus, meliputi Denaturasi (95oC selama 15 detik), annealing, dan elongation (72oC selama 10 detik). Berdasarkan hasil identifikasi molekuler di peroleh tiga belas jenis mikroorganisme yang terdiri dari empat jenis Bakteri dan sembilan jenis Kapang.
Relato de experiência do projeto integrador no desenvolvimento do software para gerenciar feiras de alimentos do Município de Iporá
Authors: Portilho Filipe Jesus , Grande Eliana Tiba Gomes , Lima Kellyanny Chaves , Leite Lucas Venâncio Bernardo Costa
Published: January 2021

Pensar em currículo integrado é pensar em integração de experiências e conhecimentos enriquecedores, através da prática pedagógica assistida, planejamento coletivo, criação de projetos integradores, programas de iniciação científica e de extensão, projetos de pesquisa, práticas profissionais integradas, entre outras práticas inovadoras utilizadas para o alcance dos objetivos do curso. Este projeto integrador é sobre o desenvolvimento de um software para gerenciar as feiras de alimentos do município de Iporá-GO. O objetivo é desenvolver um aplicativo que facilite a vida das pessoas que tem o costume de frequentar as feiras de alimentos, mostrando as bancas com seus devidos produtos, a sua origem e o valor, bem como melhorar a relação entre consumidores e a agricultura familiar. No primeiro momento, levantou-se as feiras realizadas na cidade de Iporá e o perfil dos comerciantes. No segundo momento, fez a análise do sistema com os dados levantados. No terceiro e último momento, desenvolveu o aplicativo na linguagem Delphi com banco de dados SQlite. O aplicativo mostrou-se que atende ao problema proposto e está de acordo com os conceitos do UX.
Pembuatan Pakan Ternak sebagai Alternatif Pemanfaatan Bonggol Jagung dan Kulit Kopi di Desa Batur Kecamatan Gading Kabupaten Probolinggo
Authors: Sahidah Ahmad
Published: January 2021

Batur is a village located at Gading, Probolinggo, East Java in which the recent condition of economics is dominated by agriculture and husbandry. The animal husbandry potentials of Batur include cow, goat, fowl. Meanwhile, in the agricultural sector, this village has corn, grain, coffe, vine, coconut, sugar palm tree. Based on that potentials, the training program of making the gnarl of corns and shell of coffe into the feed for animals will be necessary. The participants of the training are delegation of cattlemans in every villages of Batur, such as Klepo, Krajan, Rabunan, Tanah Merah. This program is to make sure that every delegation of the villages will be representation of the social empowerment.Keywords: Training, Feeds for Animals, Social Empowerment
Camping It up with EMI: The Politics of the Intersection of British Film Production with the Notion of Camp
Authors: Bradley Peri
Published: January 2021

This article will explore two camp films released by EMI: the Danny La Rue star vehicle Our Miss Fred (1972) and the Village People biopic Can’t Stop the Music (1980), locating them within a broader tradition of British farcical humour and their respective cultural and industrial contexts. Through an examination of how these films operated as entertainment, the article argues that the intersection of EMI Films and camp actually helped to influence and modify cultural and social attitudes, particularly with regard to the gradual acceptance of the representation of queerness in 1970s and 1980s culture.
An Unexpected Case Report of Adrenal Lymphangioma: Mimicking Metastatic Tumor on Imaging in a Patient With Pancreatic Cancer
Authors: Wan Shang , Liu Xijiao , Tian Bole , Cao Dan , Li Mao , He Yuhao , Song Bin
Published: January 2021

Adrenal lymphangioma is a very rare benign lesion worldwide and remains challenging for early diagnosis, especially when the patient has some complicated clinical disease. This is an unusual case of a 68-year-old man who was admitted to our hospital with a history of pancreatic tumor. Computed tomography (CT) images and subsequent magnetic resonance imaging (MRI) revealed a mass located in the left adrenal gland, presenting a similar enhancement pattern of the pancreatic tumor, and according to the imaging features, the patient was suspected to have an adrenal metastatic tumor originating from the pancreatic tumor. The patient underwent a surgical resection of the pancreatic tumor and the left adrenal gland. The pathologic diagnosis proved to be lymphangioma deriving from the left adrenal gland. This is the first report presenting an atypical adrenal lymphangioma mimicking a metastatic tumor of pancreatic origin, which might be suggestive in the diagnosis of adrenal lesions and the subsequent clinical treatment, especially when patient has a particular medical history. As we know, imaging examination is helpful for accurate preoperative diagnosis; however, the diagnosis of malignant tumor solely based on imaging procedures should be made cautiously by radiologists.
IL-23 Contributes to Campylobacter jejuni-Induced Intestinal Pathology via Promoting IL-17 and IFNγ Responses by Innate Lymphoid Cells
Authors: Jing Xi , Korchagina Anna A. , Shein Sergey A. , Muraoka Wayne T. , Koroleva Ekaterina , Tumanov Alexei V.
Published: January 2021

Human pathogen Campylobacter jejuni is a significant risk factor for the development of long-term intestinal dysfunction although the cellular and molecular mechanisms remain scantily defined. IL-23 is an emerging therapeutic target for the treatment of inflammatory intestinal diseases, however its role in C. jejuni-driven intestinal pathology is not fully understood. IL-10 deficient mice represent a robust model to study the pathogenesis of C. jejuni infection because C. jejuni infection of mice lacking IL-10 results in symptoms and pathology that resemble human campylobacteriosis. To determine the role of IL-23 in C. jejuni-driven intestinal inflammation, we studied the disease pathogenesis in IL-23-/- mice with inhibited IL-10Rα signaling. These mice exhibited reduced intestinal pathology independent from bacterial clearance. Further, levels of IFNγ, IL-17, IL-22, TNF, and IL-6 were reduced and associated with reduced accumulation of neutrophils, monocytes and macrophages in the colon. Flow cytometry analysis revealed reduced production of IL-17 and IFNγ by group 1 and 3 innate lymphoid cells. Thus, our data suggest that IL-23 contributes to intestinal inflammation in C. jejuni infected mice by promoting IL-17 and IFNγ production by innate lymphoid cells.
Applying Single-Cell Technology in Uveal Melanomas: Current Trends and Perspectives for Improving Uveal Melanoma Metastasis Surveillance and Tumor Profiling
Authors: Wang Mona Meng , Chen Chuanfei , Lynn Myoe Naing , Figueiredo Carlos R. , Tan Wei Jian , Lim Tong Seng , Coupland Sarah E. , Chan Anita Sook Yee
Published: January 2021

Uveal melanoma (UM) is the most common primary adult intraocular malignancy. This rare but devastating cancer causes vision loss and confers a poor survival rate due to distant metastases. Identifying clinical and molecular features that portend a metastatic risk is an important part of UM workup and prognostication. Current UM prognostication tools are based on determining the tumor size, gene expression profile, and chromosomal rearrangements. Although we can predict the risk of metastasis fairly accurately, we cannot obtain preclinical evidence of metastasis or identify biomarkers that might form the basis of targeted therapy. These gaps in UM research might be addressed by single-cell research. Indeed, single-cell technologies are being increasingly used to identify circulating tumor cells and profile transcriptomic signatures in single, drug-resistant tumor cells. Such advances have led to the identification of suitable biomarkers for targeted treatment. Here, we review the approaches used in cutaneous melanomas and other cancers to isolate single cells and profile them at the transcriptomic and/or genomic level. We discuss how these approaches might enhance our current approach to UM management and review the emerging data from single-cell analyses in UM.
Matrix Inequalities Based Robust Model Predictive Control for Vehicle Considering Model Uncertainties, External Disturbances, and Time-Varying Delay
Authors: Liu Wenjun , Chen Guang , Knoll Alois
Published: January 2021

In this paper, we design a robust model predictive control (MPC) controller for vehicle subjected to bounded model uncertainties, norm-bounded external disturbances and bounded time-varying delay. A Lyapunov-Razumikhin function (LRF) is adopted to ensure that the vehicle system state enters in a robust positively invariant (RPI) set under the control law. A quadratic cost function is selected as the stage cost function, which yields the upper bound of the infinite horizon cost function. A Lyapunov-Krasovskii function (LKF) candidate related to time-varying delay is designed to obtain the upper bound of the infinite horizon cost function and minimize it at each step by using matrix inequalities technology. Then the robust MPC state feedback control law is obtained at each step. Simulation results show that the proposed vehicle dynamic controller can steer vehicle states into a very small region near the reference tracking signal even in the presence of external disturbances, model uncertainties and time-varying delay. The source code can be downloaded on https://github.com/wenjunliu999.
Iron Content in Deep Gray Matter as a Function of Age Using Quantitative Susceptibility Mapping: A Multicenter Study
Authors: Li Yan , Sethi Sean K. , Zhang Chunyan , Miao Yanwei , Yerramsetty Kiran Kumar , Palutla Vinay Kumar , Gharabaghi Sara , Wang Chengyan , He Naying , Cheng Jingliang , Yan Fuhua , Haacke Ewart Mark
Published: January 2021

Purpose

To evaluate the effect of resolution on iron content using quantitative susceptibility mapping (QSM); to verify the consistency of QSM across field strengths and manufacturers in evaluating the iron content of deep gray matter (DGM) of the human brain using subjects from multiple sites; and to establish a susceptibility baseline as a function of age for each DGM structure using both a global and regional iron analysis.

Methods

Data from 623 healthy adults, ranging from 20 to 90 years old, were collected across 3 sites using gradient echo imaging on one 1.5 Tesla and two 3.0 Tesla MR scanners. Eight subcortical gray matter nuclei were semi-automatically segmented using a full-width half maximum threshold-based analysis of the QSM data. Mean susceptibility, volume and total iron content with age correlations were evaluated for each measured structure for both the whole-region and RII (high iron content regions) analysis. For the purpose of studying the effect of resolution on QSM, a digitized model of the brain was applied.

Results

The mean susceptibilities of the caudate nucleus (CN), globus pallidus (GP) and putamen (PUT) were not significantly affected by changing the slice thickness from 0.5 to 3 mm. But for small structures, the susceptibility was reduced by 10% for 2 mm thick slices. For global analysis, the mean susceptibility correlated positively with age for the CN, PUT, red nucleus (RN), substantia nigra (SN), and dentate nucleus (DN). There was a negative correlation with age in the thalamus (THA). The volumes of most nuclei were negatively correlated with age. Apart from the GP, THA, and pulvinar thalamus (PT), all the other structures showed an increasing total iron content despite the reductions in volume with age. For the RII regional high iron content analysis, mean susceptibility in most of the structures was moderately to strongly correlated with age. Similar to the global analysis, apart from the GP, THA, and PT, all structures showed an increasing total iron content.

Conclusion

A reasonable estimate for age-related iron behavior can be obtained from a large cross site, cross manufacturer set of data when high enough resolutions are used. These estimates can be used for correcting for age related iron changes when studying diseases like Parkinson’s disease, Alzheimer’s disease, and other iron related neurodegenerative diseases.
Liq_ccRCC: Identification of Clear Cell Renal Cell Carcinoma Based on the Integration of Clinical Liquid Indices
Authors: Zhao Jianhong , Wu Jiangpeng , Wei Jinyan , Su Xiaolu , Chai Yanjun , Li Shuyan , Wang Zhiping
Published: January 2021

Currently, preoperative diagnosis and differentiation of renal clear cell carcinoma and other subtypes remain a serious challenge for doctors. The liquid biopsy technique and artificial intelligence have inspired the pursuit of distinguishing clear cell renal cell carcinoma using clinically available test data. In this work, a method called liq_ccRCC based on the integration of clinical blood and urine indices through machine learning approaches was successfully designed to achieve this goal. Clinically available biochemical blood data and urine indices were collected from 306 patients with renal cell carcinoma. Finally, the integration of 18 top-ranked clinical liquid indices (13 blood samples and 5 urine samples) was proven to be able to distinguish renal clear cell carcinoma from other subtypes of renal carcinoma by cross-valuation with an AUC of 0.9372. The successful introduction of this identification method suggests that subtype differentiation of renal cell carcinoma can be accomplished based on clinical liquid test data, which is noninvasive and easy to perform. It has huge potential to be developed as a promising innovation strategy for preoperative subtype differentiation of renal cell carcinoma with the advantages of convenience and real-time testing. liq_ccRCC is available online for the free test of readers at http://lishuyan.lzu.edu.cn/liq_ccRCC.