bluuebunny/crossref_metadata_2025 huggingface dataset:
Integration with Spilanthes Achmella in fibromyalgia syndrome: open-label study six months after the treatment
Authors: Bardelli Marco , Gentileschi Stefano , Frediani Bruno , Benucci Maurizio
Published: November 2021

Fibromyalgia, also known as fibromyalgia syndrome (FM), is a rheumatic syndrome which is currently considered idiopathic and multifactorial. It causes an increase in muscle tension associated with stiffness, asthenia (loss of strength with fatigue), cognitive impairment, insomnia or sleep disorders and impaired sensitivity to stimuli. We performed a prospective evaluation of 149 patients suffering from fibromyalgia syndrome according to the 2010 ACR Criteria. Patients were clinically assessed at baseline and after 1-3-6 months, using the patient-reported outcomes thermometer - 5-item scale (5TPROs). In addition to their therapy, all patients received a supplementation with Spilanthes Achmella. This food supplement is characterized by synergy of bioactive compounds, such as Acmella oleracea extract, and has neurotrophic, anti-inflammatory and pain-relieving effects. All patients were randomized at baseline to receive Spilanthes Achmella, 2 tablets per day for one month and subsequent tapering to 1 tablet per day for 5 months. At six months, a statistically significant difference in the following parameters was shown: pain P<0.001, fatigue P<0.001, physical function P<0.001, depression: P<0.001, general health P<0.001. Conversely, the post-hoc analysis data did not report any significant difference for the parameters between the third and sixth month. A drug-sparing effect was observed (P<0.001). The posthoc analysis revealed a significant difference between T0 and T3 P=0.00066 and between T0 and T6 P=0.00008. Our data indicate that supplementation with Spilanthes Achmella may lead to a significant improvement in pain, fatigue, physical function, depression and general health in fibromyalgia syndrome.
Direct Oral Anticoagulants: A Review for the Non-Specialist
Authors: Gunawardena Thilina
Published: November 2021

Thrombin inhibitors and direct factor Xa inhibitors represent a major breakthrough in the field of anticoagulation pharmacotherapy. These novel agents have replaced warfarin as the oral anticoagulant of choice in certain indications, as they possess equal or superior efficacy and better safety profiles. They have a quick onset of action, predictable pharmacokinetic properties and minimal drug and food interactions. So they do not require frequent blood monitoring and dose adjustments as with warfarin. Considering all the advantages, there seems to be a rapid increase in the number of patients who are started on these novel anticoagulants. In this review, we highlight the pharmacology of these direct oral anticoagulants and the evidence-based indications for their use. We aim to provide a clinical overview for the non-specialist who may be called upon to manage a patient who is currently on one of these novel anticoagulants.
The Effects of 8-Week Resistance and Endurance Trainings on Bone Strength Compared to Irisin Injection Protocol in Mice
Authors: Shahabi Shirin , Esfarjani Fahimeh , Reisi Jalil , Momenzadeh Sedigheh , Jami Mohammad-Saeid , Zamani Saeed
Published: November 2021

Background:

Osteoporosis is a prevalent elderly complication that is characterized by decreased bone mineral density and increased fracture risk because of dysregulation in bone mineralization and resorption. Physical activity can enhance bone strength by exerting mechanical forces and myokines. Irisin is a myokine that is increased following physical exercise and can affect bones. In this study, 8 weeks of resistance and endurance exercises are applied in mice compared to irisin injection to assess the contribution of the protocols and this myokine to bone strength.

Materials and Methods:

Thirty-five male NMRI mice were separated into five groups; control, placebo, irisin injection, resistance exercise, and endurance exercise. 8-week of exercise protocols and irisin injection protocol (100 μg/kg/week) was applied. Plasma irisin concentration and bone strength were measured using enzyme-linked immunoassay and 3-point bending assay, respectively. Statistical analyses were done through one-way ANOVA and Tukey test, and P < 0.05 was considered the significant difference.

Results:

Serum irisin concentration and bone strength in resistance exercise and irisin-injected groups were significantly higher than control and placebo groups (P < 0.0001). Serum irisin concentration, but not bone strength, of the endurance exercise group was also significantly higher than control and placebo groups (P < 0.0001) but lower than resistance and irisin-injected groups.

Conclusion:

Resistance exercise and irisin injection, but not endurance exercise, are likely to be effective in increasing bone strength. There may be a threshold for plasma irisin level to affect bones which the applied protocols of irisin injection and resistance exercise but not endurance exercise can reach.
The Role of Cyclooxygenase 2 in the Cognitive Impairment Induced by Alcohol or Stress in Rats
Authors: Hosseini-Sharifabad Ali , Alaei Zahra , Rabbani Mohammad , Seyedabadi Mohammad
Published: November 2021

Background:

Cognitive impairment is an unpleasant and progressive mental disorder characterized by learning and memory disabilities. Stress and alcohol are two known environmental factors that increase cognitive impairment. This study was designed to evaluate the relative role of cyclooxygenase 2 in alcohol or stress-induced cognitive impairment.

Materials and Methods:

Male Wistar rats were randomly divided into groups with six rats in each. The groups included sham, control, alcohol (15% ethanol in drinking water), and restraint stress (restraint 6 h per day). Three separated groups received celecoxib at a dose of 20 mg/kg in addition to those listed above. The treatments continued daily for 28 days. The object recognition task (ORT) and Morris water maze (MWM) are used to evaluate the learning and memory.

Results:

Alcohol or restrain stress significantly increased the time and distance needed to find the hidden platform in MWM. Furthermore, they decreased the recognition index in ORT compared to the control group. Administration of celecoxib significantly decreased the required time and traveled distance to reach the platform in alcohol-treated animals but not in the stress-exposed rats. Celecoxib also significantly increased the recognition index both in alcohol- or restraint stress-exposed animals.

Conclusion:

We found that either alcohol or restraint stress impairs memory in rats. In MWM, celecoxib improved the alcohol-induced memory impairment but could not show a reduction in memory deterioration due to restraint stress. In ORT, celecoxib reversed memory impairment due to both alcohol and restraint stress.
Yoga-Based Lifestyle Intervention as a Potential Adjuvant in Addressing Anxiety, Fear, Depression, and Perceived Health in Mild-to-Moderate COVID-19 Patients. A Pilot Study
Authors: Russel Jainraj , Manavalan N. , Alli M , Subramanian Kahlil , Gayathiri Nisha , K Nair Pradeep M
Published: November 2021

Introduction:

Coronavirus infection (COVID-19) has led to a serious public health crisis that has affected both physical and mental health. As we are racing toward a solution for containing the virus, there is a profound need to address the mental health impact of COVID-19 such as anxiety, stress, and depression. The present study evaluates the impact of yoga on mental health issues arising in COVID-19 pandemic.

Materials and Methods:

Patients who are diagnosed as COVID-19 by polymerase chain reaction and graded as mild-to-moderate COVID-19 as per the ICMR criteria were enrolled for adjuvant yoga and naturopathy-based lifestyle modification, which includes postures, breath regulation, meditation, and eucalyptus essential oil inhalation for 14 days. SpO2 (saturated oxygen) and anxiety, stress, depression, fear, and health were assessed through the depression, anxiety, and stress scale (DASS) at baseline (day 1 of admission) and 7th day, as well as visual analog scale (VAS) at baseline and 7th and 14th day.

Results:

Statistically significant changes reduction were observed in DASS-21 scores and VAS scores (P < 0.05) but not on SpO2. Slight increase in mean anxiety, depth of fear, sleep disturbance, and health status was observed in VAS between 7th and 14th day, which was statistically nonsignificant.

Discussion:

Supervised yoga sessions are reported to be of significant impact in alleviating the mental health issues in COVID-19 compared to nonsupervised sessions. Our results suggest the inclusion of yoga therapy into COVID-19 care as an adjuvant considering its impact on mental health. However, future randomized control trials are warranted with more specific end points to ensure enhanced acceptance of yoga in scientific community.
A Case–Control Study to Evaluate the Etiological Factors of Vataja Pandu
Authors: Mohan Rijin , Gopikrishna S. , Kumar Saranya S
Published: November 2021

Background:

Vataja Pandu is a common clinical condition, only generalized etiological factors of Pandu (anemia) are explained in Ayurvedic textbooks. Many studies related to Pandu are carried out, but there is a lacuna of convincing research on risk analysis of each causative factor.

Objective:

To evaluate the involvement of various etiological factors mentioned in Ayurvedic classics in the causation of etiopathogenesis of Vataja Pandu.

Materials and Methods:

The present study was a case–control study to determine the exposure of risk factors of Vataja Pandu where 31 subjects fulfilling the criteria of Vataja Pandu were included for the study and considered as case group. Thirty-one healthy individuals were selected from the same geographical area and were taken as the control group detailed history and a questionnaire for Vataja Pandu Nidana was recorded. They were subjected to laboratory investigations. The two groups were assessed based on the questionnaire. Both the groups were analyzed by Kruskal–Wallis test. The odds ratio was calculated and level of significance was analyzed with the help of Chi-square test.

Results:

When analyzed the odds ratio, following results were obtained such as Katu Rasa (pungent taste) (risk-20.7), Tikshana Guna (penetrating quality) (risk-35.4), Ushna Guna (hot quality), and Tila Taila (sesame oil) (14.28). In Viharaja Nidanas (physical factors) Diwaswapana (day sleep) (risk-73.33), Vyavaya (risk-12.13). Among Manasika Nidana (psychological causes), Chinta (thoughts) (risk-10.4), Srama (stress) and Bhaya (phobia) (risk-8.3), and Krodha (anger) (risk-4.44) show risk for developing Vataja Pandu.

Conclusion:

Among Nidanas, consumption of Katu Rasa Tikshana, Ushna Guna, Nispava, Tila Taila, Pinyaka, indulgence in Divaswapna, Nidranasha, Vyavaya, Ati Vayayama, Vegadharana, Chinta, Srama and Bhaya and Krodha show significant role in causation of Vataja Pandu when compare to control group.
A Randomized Comparative Clinical Study on Tamaka Shwasa (bronchial asthma) with Vamana and Virechana along with Shamana therapy
Authors: Babu G. , Lal Meena Hari Mohan , Joshi Ram Kishor , Bhatnagar Anu , Mutha Rashmi , Padhar Bharat Chhaganbhai , Gautam Shankar
Published: November 2021

Introduction:

Tamaka Shwasa (TS) is mentioned as one of the varieties among five types of Shwasa Roga as a “Swatantra Vyadhi” and has its own etiology, pathology, and management which resembles with bronchial asthma. Asthma affects about 6% of children and 2% of adults in India's 1.31 billion population. In TS, two treatment modalities Shodhana and Shamana have been explained. Hence, an attempt had been made to clinically compare the result of Vamana Karma and Virechana Karma along with the same Shamana drugs, i.e. Shrungyadi Churna with Guduchyadi Kashaya.

Methodology:

This study was an open comparative clinical trial with sample size 100 patients (50 in each group) for duration of 60 days. The intervention for Group I was Vamana Karma, whereas for Group II was Virechana Karma, followed by Shamana Chikitsa in both groups. Required hematological, radiological and routine examinations, pulmonary function tests, Asthma Control Questionnaire, St. George's Respiratory Questionnaire, and other parameters were assessed for the clinical evaluation.

Results and Discussion:

In both group, the parameters such as Asthma Control Questionnaire, SGRQ-C score, Peak expiratory flow rate (PEFR), Forced expiratory volume in one second (FEV1), Hemoglobin, Total leukocyte count, Eosinophils, Erythrocyte sedimentation rate and Absolute eosinophil count have shown significant (P < 0.0001) improvement. In comparison to Group I (relief percentage range from 46% to 92.68%), Group II treatment has shown better results in the relief (60%–90%) of all the clinical parameters of Tamaka Swasa (Bronchial asthma). No significant adverse effects have been noted throughout the study.

Conclusion:

Both Vamana and Virechana along with administration of Shamana drugs have statistically highly significant effect in TS (Bronchial asthma). However, the Virechana shows better relief in clinical symptoms as compared to Vamana.
Pterygium in Rural Andean Ecuador
Authors: Bal Sila , Marjane Sarah , Gonzalez Carlos , Smith Zachary , Higgins Charlene , Miller-Suchet Lucy , Binenbaum Gil
Published: November 2021

Background:

Pterygium is an ocular surface lesion that causes chronic eye irritation and eventually, vision impairment. Pathologically, prolonged ultraviolet (UV)-induced radiation damage leads to conjunctival and limbal stem cell damage. As such, rural, high-altitude equatorial communities are at particular risk due to proximity to the sun, outdoor work, and a lack of access to eye care.

Methods:

We conducted a cross-sectional study to determine the epidemiology of pterygium in the Chimborazo region of Ecuador. Adults presenting to Clinical FIBUSPAM's medical clinics for both ocular and nonocular reasons were examined by optometrists/ophthalmologists to identify pterygium. Affected patients completed a questionnaire about self-reported known risk factors, treatment, and barriers to care, and received UV-blocking sunglasses.

Results:

Of 296 patients, 165 (55%) had pterygium. The mean age was 60.2 years (range 19–88), 69% were female; 63% had unilateral pterygia, and 37% had bilateral pterygia. Symptoms occurring daily included severe photophobia (36%), foreign body sensation (28%), eye pain (24%), burning (31%), and itching (28%). In addition, 40% reported concern about eye appearance. Risk factors included spending >5 h outdoors each day working (93%), smoking (8%), and alcohol (14%). For prophylaxis, while 91% routinely wore hats outdoors, only 16% used sunglasses. For treatment, 30% used eye drops, of which two-thirds were natural remedies. About 93% wanted treatment (medications or surgical removal), 78% were concerned about access to treatment, and 43% reported cost as the major concern.

Conclusions:

Pterygium is highly prevalent (55%) among adults presenting for care in community health clinics in the Chimborazo Province of Ecuador. This treatable and potentially preventable cause of ocular irritation and vision loss greatly impacts the quality of life in this region. This and similar communities would benefit from improved education and outreach through care delivery models that bring affordable prevention and eye care services closer to home.
Sulla flessione indoeuropea
Authors: Gendre Renato
Published: November 2021

Nella recensione, che ha dedicato ad un importante libro di E. Benveniste, G. Bonfante osserva che "lasformas véd. smáh imáh, etc., que son regulares, según su teoría, no las recuerda Benveniste''. Dunque, forme del tipo scr. smáh,., ie. *smés si possono analizzare perfettamente per mezzo della teoria di E. Benveniste che accoglie, sviluppandola ulteriormente, la proposta di J. Kurylowicz: ie. *smés < *s-m-és < *Əes­ em-és
Aegyptio-afroasiatica VIII : first Version
Authors: Takacs Gabor
Published: November 2021

The present paper represents the eighth part of a series of contributions to com­ parative Afroasiatic lexicology primarily from the viewpoint of Egyptian. This series is the first fruit of the work on a newly begun greater project for the Comparative-Etymo­ logical Vocabulary of Egyptian pursued by the author at the Egyptological Department of Eotvos Lorand University, Budapest, Hungary.
Kasabalaşmış Bir Köy Monografisi: Sarayköy
Authors: KALAYCI Hakkı
Published: November 2021

Monografi tekniği, sosyoloji ve diğer sosyal bilim dallarının özellikle halk bilimi ve kültür araştırmacılarının da kullandığı bir teknik olarak bilimsel alanlarda özel bir konu veya sorun üzerine yapılan incelemeleri ifade eden bir saha çalışma tekniğidir. Daha çok küçük sosyal gruplar ya da şahıslar üzerine de uygulanabilen bu teknik, köylerin sosyal yapısını ve kültürel özelliklerini anlamak için sıkça kullanılmaktadır. Köylere ait yapılan sosyolojik araştırmalar ve tarihsel kaynaklarda ifade edilen bilgiler ışığında, köylerimizin genelde birbirine benzer süreçlerden geçtiği görülmektedir. Geçim sıkıntısı başta olmak üzere köy işlerine ait her türlü zorluklar, kestirilemeyen bir gelecek, köylerde yaşamı zorlaştıran temel faktörlerdir. Tarımsal modernizasyona geçilememesi, hızlı nüfus artışı ile makineli tarım sonrası toprağın genel nüfusa yetmeyip geçim sıkıntısına düşülmesi, her aşamadaki eğitim talepleri, sağlıkla ilgili temel beklentiler, köye ait işlerin emek gücüne dayalı zor işler olması gibi köye ait ve sosyolojide itici faktörler olarak ifade edilen sebepler bunların en önemlileridir. Çalışmamıza konu olan Sarayköy, Türkiye’nin diğer köylerinde yaşanan sosyal gerçekliklerle benzer süreçlerden geçmiş ve benzer sorunlar yaşamış bir köydür. Çankırı iline bağlı Eldivan ilçesinin bir köyü olan Sarayköy monografi çalışmamızda, köyün kısa bir tarihi, konumu, nüfusu, eğitim, ulaşım, geçimlik faaliyetleri, gelenek ve görenekleri, evlenme adetleri ve göç gibi faktörler üzerine bilgiler derlenmeye çalışılmıştır.
An interpretative phenomenological analysis exploring the transition from army to civilian life.
Authors:   , Jones Alice
Published: November 2021

This thesis presents an Interpretative Phenomenological Analysis (IPA) exploring the transition from army to civilian life. The research purpose was to explore the experiences of ex-army personnel of their transition from army to civilian life by building an in-depth picture of each participant’s experience of transitioning from the army to civilian life, as well as an understanding of how they felt about their time in the army. The following research questions were used to guide the research, Question 1: How do ex-army personnel perceive their experience of their transition from military to civilian life? Question 2: How do ex-army personnel adjust to a civilian lifestyle? Question 3: How do ex-army personnel make sense of their identity during their transition to civilian lifestyle? Question 4: How do ex-army personnel perceive support could be further developed or introduced, to facilitate individuals in the transition from military to civilian life? The thesis addressed three research aims, Aim 1: to examine how ex-army personnel perceive their experience of their transition from military to civilian life, Aim 2: to explore how ex-army personnel adjust to a civilian lifestyle, Aim 3: to develop an interpretation of the best ways in which to support ex-army personnel during their transition to civilian life. The three aims were achieved through the use of an IPA approach to the analysis of 9 interviews. Participants were individuals who had served in the army and experienced the transition from army to civilian life first hand. Nine master themes were developed as a result of the analysis. The nine master themes identified were: Identity, Control, Personality, Perception of the army, Wellbeing, Civilian lifestyle, Civilian connection, Army life, and Support. In its unique contribution to knowledge, this thesis builds upon the existing quantitative research on the topic of the transition from army to civilian life creating further depth and understanding. It explores how individuals perceive their transition experience and how they made meaning of this in their reflections. In addition to this, it uses the examination and evaluation of the transition experience to develop an interpretation of how ex-army personnel may be better supported in their transition to civilian life.
Certificate complexity and symmetry of nested canalizing functions
Authors: Li Yuan , Ingram Frank , Zhang Huaming
Published: November 2021

Boolean nested canalizing functions (NCFs) have important applications in
molecular regulatory networks, engineering and computer science. In this paper,
we study their certificate complexity. For both Boolean values $b\in\{0,1\}$,
we obtain a formula for $b$-certificate complexity and consequently, we develop
a direct proof of the certificate complexity formula of an NCF. Symmetry is
another interesting property of Boolean functions and we significantly simplify
the proofs of some recent theorems about partial symmetry of NCFs. We also
describe the algebraic normal form of $s$-symmetric NCFs. We obtain the general
formula of the cardinality of the set of $n$-variable $s$-symmetric Boolean
NCFs for $s=1,\dots,n$. In particular, we enumerate the strongly asymmetric
Boolean NCFs.
Implementation of participatory pre-collection in the sustainable management of household solid waste: case of the district of Douala V in Cameroon
Authors: Nguema Paul Fabrice , TSOBGHO Cédric , MOUNIR Zakari-Mohamadou
Published: November 2021

EPI sciences

The main objective of this study in the district of Douala V is to set up participatory pre-collection of household solid waste which, by protecting the environment, promotes the recovery of this waste. More specifically, the aim was to make an inventory of solid waste management, to raise awareness of households on participatory pre-collection, to describe the technical organization of the service and to evaluate the parameters of financial analysis for a pre-collection activity. To do this, available documents, direct observations, interviews and survey form were used. The main results of this study showed that the daily production or ratio of one inhabitant of Douala V is 1.05kg/hab/jour; the annual production is estimated at 363,870 tons. The low collection rate of about 23% was observed. With regard to household sensitization, 43% of the households surveyed are willing to pay for the pre-collection service and 52% are against and 5% are uninformed. The provisional financial analysis is based on one year; the investment cost is estimated at 3 327 400 CFA (5079 €). Overall, it appears that the solid waste collection rate in Douala V is below average, so it appears that pre-collection and recovery of household solid waste have a major role to play in the solid waste management system.

Cette étude déroulée dans l’arrondissement de Douala V a pour objectif principal de mettre sur pied la pré-collecte participative des déchets solides ménagers qui en protégeant l’environnement, favorise une valorisation de ces déchets. Il s’agissait plus spécifiquement de faire un état de lieux de la gestion des déchets solides, de sensibiliser les ménages sur la pré-collecte participative, décrire l’organisation technique du service et d’évaluer les paramètres d’analyse financière pour une activité de pré-collecte. Pour ce faire, des documents disponibles, observations directes, entretiens et fiche d’enquête ont été utilisés. Les principaux résultats de cette étude ont montré que la production journalière ou ratio d’un habitant de Douala V est de 1,05kg, la production annuelle est estimée à 363 870,45 tonnes. Le taux de collecte faible d’environ 23%. Pour ce qui est de la sensibilisation des ménages, 42,66% des ménages enquêtés sont prêts à payer pour le service de pré-collecte et 52,33% sont contre et 5% sont sans avis. L’analyse financière prévisionnelle est basée sur une année, le coût d’investissement s’estime à deux mille huit cent quatre-vingt-onze Euro (2 891 Euro). Il ressort globalement que le taux de collecte des déchets solides à Douala V est en dessous de la moyenne, il apparait donc que la pré-collecte et la valorisation des déchets solides ménagers ont un rôle majeur à jouer dans le système de gestion des déchets solides.
Socioeconomic impacts of sand harvesting along the Sanaga River in Nkol’Ossananga locality (Yaoundé-Cameroon): a vision toward a mechanized operation for sustainable exploitation
Authors: Happi Tientcheu William , Ekengoue Clautaire , Lele Rodrigue , Oluchukwu Duluora , Messanga Benoit , Dongmo Armand
Published: November 2021

This paper presents the impacts of Nkol’Ossananga sand harvesting on social live and local economy based on field investigations and data analysis. Laboratory analysis of sand samples from the site has shown that the cleanliness of the Nkol’Ossananga sand nears 100%. This means that Nkol’Ossananga sand is pure and clean, most appropriate for house constructions and building engineering. The activity produces incomes to all actors of the chain value and government. Incomes generated are used by artisans to build their houses, buy some electronic devices, and take care of their families or to capitalize in their business investigation. In spite of the positive impacts presumed, Nkol’Ossananga sand harvesting also stands as the origin of many negative impacts including cultural brewing, delinquency, precocious abandon of studies and abandon of agriculture. The exploitation is done with rudimentary tools and poor technics thereby exposing artisans to several risks and illnesses. For sustainable exploitation, a mechanized operation has to be implemented. This kind of exploitation is the one that will improve the working conditions, increase production and incomes of workers as similar as that of government, and also reduces negative environmental impacts. Key words: Nkol’Ossananga sand, rudimentary tools and poor technics, incomes, negative impacts, sustainable exploitation, mechanized operation.

Cet article présente les impacts sociaux et économiques de l’exploitation artisanale du sable de Nkol’Ossananga sur la base d’enquêtes de terrain et d’analyses de données. L’analyse en laboratoire des échantillons de sable collectés sur le site a montré que la propreté du sable de Nkol’Ossananga avoisine 100%. Ce qui signifie que le sable de Nkol’Ossananga est approprié pour le BTP et le génie civil. L'activité génère des revenus importants à tous les acteurs de la chaîne de production et le gouvernement. Les revenus générés sont utilisés par les artisans pour se faire construire leur maison d’habitation, acheter des appareils électroniques, prendre soin de leur famille ou alors sont capitalisés dans le commerce. Malgré les impacts positifs susmentionnés, l’exploitation artisanale du sable de Nkol’Ossananga est également source du brassage culturel, de la délinquance juvénile et de l’abandon précoce des études. Pour une exploitation durable, l’exploitation semi-mécanisée est envisageable. Ce type d'exploitation est celui qui pourra améliorer les conditions de travail des artisans, augmenter leur production et leurs revenus au même titre que ceux du gouvernement, et réduira par ricochet les impacts négatifs.
Meteorological reports in the Perspective Automated Artillery Fire Support Control System
Authors: Blaha Martin , Potužák Ladislav
Published: November 2021

The Czech Republic, as a member of international organizations (NATO, EU, UNO), with respect to current global security environment, employs the units of the army both at its own state territory and outside the Czech Republic in multinational forces operations. The article focuses on preparation of meteorological reports of future Automated Command, Control, and Information system (C2I) in conditions of the Army of the Czech Republic. The issue of automated command, control, and information systems is of high importance in the solving of asymmetrical operations tasks today and in the upcoming future. Define the basic resources for creation of meteorological reports of NATO standards in Network Enabled Capabilities (NEC) conditions. The authors define group of meteorological report for designing a new and by the Army of the Czech Republic required sophisticated Automated Fire Support Control System of Artillery meeting NATO standards in Network Enabled Capabilities (NEC) conditions. The article represents section of a huge defensive research project of Ministry of Defence of the Czech Republic and the Army of the Czech Republic solved by leading scientists of the University of Defence in Brno.
Practical Implementation of New Algorithm for Restricting Data Fusion in Cloud Computing with Use of Information Kalman Filtering
Authors: Mohamadzadeh Mohamadreza
Published: November 2021

These days’ lots of technologies migrate from traditional systems into cloud and similar technologies; also we should note that cloud can be used for military and civilian purposes [3]. On the other hand, in such a large scale networks we should consider the reliability and powerfulness of such networks in facing with events such as high amount of users that may login to their profiles simultaneously, or for example if we have the ability to predict about what times that we would have the most crowd in network, or even users prefer to use which part of the Cloud Computing more than other parts – which software or hardware configuration. With knowing such information, we can avoid accidental crashing or hanging of the network that may be cause by logging of too much users. In this paper we propose Kalman Filter that can be used for estimating the amounts of users and software’s that run on cloud computing or other similar platforms at a certain time. After introducing this filter, at the end of paper, we talk about some potentials of this filter in cloud computing platform. In this paper we demonstrate about how we can use Kalman filter in estimating and predicting of our target, by the means of several examples on Kalman filter. Also at the end of paper we propose information filter for estimation and prediction about cloud computing resources.
Economic Relationships Between Selling and Rental Prices in the Italian Housing Market
Authors: Morano Pierluigi , Manganelli Benedetto , Tajani Francesco
Published: November 2021

In this paper the relationship between price and rent dynamics in the Italian housing market is studied. The aim is reached through the implementation of a multivariate autoregressive model (VAR), that makes it possible to explain the interdependencies of multiple time series. The analysis considers a series of macroeconomic variables in the model that in the deductive interpretation of the phenomenon and on the basis of other experiences in current literature, were evaluated as potential keys to understanding the relationship between prices and rents. The variables selected, along with residential realestate prices and real residential rents, were: the real short term interest rate, the time series of the annual differences between the actual and the expected Gross Domestic Product, real investments in housing. The data series cover the period from 1980 to 2008. The results obtained show some peculiarities of the Italian real estate market.
Basic Characteristics of Small and Medium-sized Enterprises in Terms of Their Strategic Management
Authors: Březinová Monika
Published: November 2021

The strategic management represents current direction of management. It is applied in all types of enterprises, including small and medium sized ones. Using principles of process management within SMEs has its limitations caused mainly by the size of the enterprise and the related focus on operational management. Other specifics are function accumulation, informal leadership, preference of oral communication to written, etc. Nevertheless, implementation of strategic management can increase competitiveness, reduce costs, improve decision-making, facilitate implementation of the employee motivation system, shorten delivery times, raise quality of customer satisfaction, etc. The aim of this article is to find out how to what extent SMEs implement the principles of strategic management.
Non-linearity in Equity Market Timing: Empirical Evidence From the UK
Authors: Hussain Hafezali Iqbal , Ayub Meor Azli , Zainol Zurinahni
Published: November 2021

This paper empirically tests the market timing theory to prove that issuing behavior of managers is non-linear. Consistent with the literature we show that mangers increase use of equity to finance their deficit when equities are overvalued and resort to a higher proportion of debt when equities are undervalued. Our results further suggest that mangers however exhibit a distinctive pattern when timing the market. The increase in reliance on equity to finance their deficit during periods of equity overvaluation is non-linear and only significant when the degree of overvaluation is not excessive. Furthermore, during periods of undervaluation managers resort to higher levels of leverage to finance their deficit only when undervaluation levels are excessive. This has serious implications on the ability of the equity market timing as a stand-alone theory in explaining capital structure decisions and poses some interesting implications on the debt-equity choice question when financing the deficit.
AĞIR VASITA HAVA KURUTUCU TEST CİHAZI PARAMETRELERİNİN BELİRLENMESİ VE PERFORMANSA ETKİLERİNİN DEĞERLENDİRİLMESİ
Authors: ELMAS Fatih Mehmet Mesut , CAN Ahmet
Published: November 2021

Ağır vasıtalarda debriyaj, süspansiyon, fren gibi bileşenlerin çalışması için basınçlı temiz hava gerekmektedir. Basınçlı hava; ağır vasıta hava kompresörleri tarafından üretilmektedir. Ancak kompresörün ürettiği basınçlı hava içerisinde sistemin çalışmasına bağlı olarak bir miktar yağ ve nem bulunmaktadır. Nem ve yağ; hava sisteminin donması, sızdırmazlık elemanlarının zarar görmesi, valf arızası ve boru tıkanıklıkları gibi arızalara yol açmaktadır. Hava kompresörünün basınçlandırdığı havadaki nem ve yağ, hata kurutucu tarafından temizlenerek tanka gitmeleri engellenmektedir. Hava kurutma işlemi; bütün basınçlı hava sistemini donmaya, içten korozyona karşı korumak ve bu şekilde sistemin işletim güvenliğini sürekli olarak sağlamak ve kullanım ömrünü uzatmak için gereklidir. Hava kurutucuların testlerinin yapılarak güvenli bir şekilde araca entegre edilmesi emniyet açısından önem arz etmektedir. Bu çalışmada bir ağır vasıta hava kurutucusu tasarımı ve üretimi gerçekleştirilerek, bu ürünün doğrulama testleri yapılmıştır. Tasarım ve üretim doğrulama için araç üzerindeki çalışma şartlarını simüle edebilen bir test cihazı tasarlanarak üretimi gerçekleştirilmiştir. Hava kurutucu mekanik olarak çalışan bir sisteme sahiptir ve içerisinde yaylar vasıtasıyla sistemin çalışması kontrol edilir. Yaylar, hava kurutucunun performansını doğrudan belirleyen bileşenler oldukları için; karakteristiklerini ve davranışlarını bilmek, hava kurutucunun performansının ölçülmesine destek olmaktadır. Ayrıca bu çalışmada, kullanılan yayların karakteristik özellikleri de analiz edilmiştir.
O uso clínico da densitometria
Authors: Eis Sergio Ragi , Zerbini Cristiano A. F.
Published: November 2021

O emprego clínico da densitometria óssea confunde-se com o desenvolvimento dos conhecimentos científicos no campo da osteoporose. Até meados dos anos 1980, a osteoporose figurava unicamente entre as manifestações humanas vinculadas a uma longa existência.
Já no início dos anos 1990, impulsionada pela possibilidade de estratificar indivíduos de acordo com o gradiente de risco para fraturas, a ciência lançou-se numa cruzada na busca de intervenções farmacológicas capazes de impedir as perdas de massa óssea características do processo de envelhecimento humano e, um pouco mais tarde, também para estimular a atividade osteogênica.
Vias de regulação do balanço ósseo foram (e vêm sendo) identificadas e novos recursos terapêuticos e diagnósticos foram desenvolvidos, alavancados pela densitometria óssea.
A definição operacional da osteoporose, ainda hoje utilizada em todo o mundo como variável insubstituível na prática médica, foi proposta em 1994 pela Organização Mundial da Saúde (OMS) (1). O critério da OMS baseia‑se em achados de densidade mineral óssea (DMO) por absorciometria de dupla emissão de raios X (DXA), limitados à coluna lombar, colo femoral, fêmur total ou rádio distal (33%). A Tabela 1 resume os critérios de estratificação propostos pela OMS.
Desde então, várias são as iniciativas para padronizar o uso clínico, interpretação e prática da densitometria. No Brasil, a Sociedade Brasileira de Densitometria Clínica (SBDens), em estreita vinculação científica com a International Society for Clinical Densitometry (ISCD), vem, desde 1993, conduzindo programas de qualificação e certificação profissionais amplamente reconhecidos pela comunidade científica.
Desarrollo de la motricidad gruesa a través de los juegos predeportivos de arnd locher
Authors: Castillo Oscar Vergara , Bolaño-García Matilde
Published: November 2021

Los aspectos relacionados con el desarrollo de la motricidad gruesa, a través de los juegos predeportivos de Arnd Locher, ocupa el centro del presente artículo, es desde esa perspectiva que se realiza un mostrar las concepciones de las diferentes investigaciones que se relacionan con la temática en estudios desde el ámbito internacional y nacional. El objetivo del artículo es analizar la incidencia de los juegos predeportivos de Arnd Locher para el desarrollo de la motricidad gruesa, utilizada como estrategia pedagógica para lograr el adecuado desarrollo corporal en los estudiantes. Se enmarcó en una metodología cualitativa – interpretativa, de tipo investigación – acción, dentro de la cual se emplearon seis (6) fases: Preparatoria, observación directa y consulta, análisis de la in formación, actividad de intervención, elaboración del informe investigativo y socialización de resultados. La población estuvo compuesta por los estudiantes del grado primero de una institución de educación en el distrito de Santa Marta. Se implementó las actividades en las clases de educación física donde se contó con la participación activa, dinámica y colaboradora de la población objeto de estudio.  Los resultados obtenidos permitieron corroborar que a través de los juegos predeportivos se puede desarrollar de manera adecuada la motricidad gruesa y esto se logra a través de procesos pedagógicos de manera planificada en el área de educación física estimulando de esta manera las capacidades y habilidades motoras como la coordinación, el equilibrio, la flexibilidad y lateralidad.
Construction Cost Overruns of Residential Building Projects in Oman: Root Cases and Mitigation Strategy
Authors: Al Jabri Mohammed , Dawood Mahmoud
Published: November 2021

Characteristics of construction project includes a specific purpose and it must meet the requirements and expectations of the client. The construction project activities are always linked together and the time required for each activity does vary. The working on the project will not complete unless there are experts from different departments ranging from site workers, civil engineers, architects, electricians, designers, project engineer, site engineer, project manager and administrative staff such as procurement department and others. One of the primary objectives is to finish the project within budget. Excess of construction costs has a negative impact on project parties. Therefore, the causes of these abuses must be identified, especially in the Sultanate of Oman. This research investigates and evaluates the root causes of the cost overrun, cost trend and financial risks related to the residential projects in Sultanate of Oman. A questionnaire has been designed to collect the primary data and literatures are studied to collect the related secondary data. The causes are categorized into three groups according to the responses of the specialists with the contractor, consultant and client .Aspects of agreement between groups were identified after analyzing the questionnaire.
Прогнозирование эффективности инвестиций в цифровизацию ядерной энергетики
Authors: Харитонов В.В. , Семенова Д.Ю. , Акинфеева Е.В.
Published: November 2021

В статье предлагается аналитическая методика прогнозирования эффективности инвестиций в цифровизацию проектирования, сооружения и эксплуатации АЭС на микроэкономическом уровне, затраты на которую влияют в конечном итоге на экономические показатели АЭС, определяющие конкурентоспособность ядерной энергетики на рынке энерго-технологий. В качестве критерия для оценки эффективности инвестиций в цифровизацию ядерной энергетики предложено считать снижение стоимости и сроков сооружения АЭС, в наибольшей степени влияющих на конкурентоспособность АЭС. Результаты расчетов приведенной стоимости электроэнергии АЭС, периода окупаемости инвестиций и нормы внутренней доходности в зависимости от наблюдаемых задержек и соответствующего роста стоимости сооружения АЭС демонстрируют резервы для их снижения за счет цифровизации бизнес-процессов жизненного цикла АЭС.
Новые подходы к построению диверсифицированной экономики: опыт Казахстана
Authors: Аубакирова Г.М. , Исатаева Ф.М.
Published: November 2021

В статье рассматриваются подходы к формированию новой модели экономического роста Казахстана – экспортно-ориентированной экономике с высокой добавленной стоимостью. Показано, что замедление трансформационных процессов в промышленности во многом обусловлено инертностью структурных экспортных изменений. Выявлены ключевые факторы, препятствующие продвижению промышленных предприятий на мировые рынки. Анализируются среднесрочные перспективы диверсификации экономики с акцентом на рост ее самодостаточности и конкурентоспособности несырьевого сектора. Обсуждаются новые меры государственного регулирования индустриально-инновационной деятельности предприятий обрабатывающей промышленности в 2021-2025 гг., учитывающие стандарты ОЭСР и передовой зарубежный опыт. Результаты исследования могут быть полезны странам с транзитной экономикой.
Исследование взаимосвязи динамики сводных макроэкономических индикаторов и динамики видов экономической деятельности в российской экономике
Authors: Суворов Н.В. , Трещина С.В. , Белецкий Ю.В.
Published: November 2021

В статье представлены результаты количественного анализа взаимосвязи динамики отдельных видов экономической деятельности и сводных макроэкономических индикаторов применительно к российской экономике в период 1995-2016 гг. Установлено наличие фактора цикличности во взаимосвязи динамики отдельных видов деятельности и макроэкономических индикаторов в исследуемый период. Проанализированы возможности использования специального класса функций времени (на основе преобразования Фурье) для моделирования экономической динамики на уровне отдельных видов деятельности.
Modelizado y estudio experimental del comportamiento de las cenizas en instalaciones industriales de combustión de biomasa con tecnología de parrilla
Authors:   , Funcia Muguerza Ibai
Published: November 2021

El presente trabajo tiene por objetivo general el desarrollo de una metodología para el análisis y predicción del comportamiento de cenizas y compuestos inorgánicos generados en la combustión de biomasa a alta temperatura (450-1300 ºC) a partir de la composición de la materia prima. Más concretamente, en esta tesis doctoral se estudia el empleo de paja de cereal como materia prima en una instalación industrial con tecnología de parrilla móvil. La metodología desarrollada se validará frente a pruebas reales realizadas en una planta de escala comercial (15-25 MWe).
Evaluación de la respuesta inmunológica funcional desarrollada frente a citomegalovirus, virus Epstein-Barr y adenovirus así como de sus elementos reguladores en pacientes que reciben un TPH alogénico
Authors:   , Vallejo Ruiz Miren
Published: November 2021

Los objetivos principales de cada bloque que compone esta tesis son: Bloque I. Identificar en sujetos sanos, el potencial regulatorio inmunológico de los agentes patógenos y farmacológicos propios de un paciente que ha sido sometido a un alo-TPH. Bloque II. Caracterizar en pacientes que reciben un alo-TPH el microambiente funcional inmunológico que protege a los pacientes frente a una infección por CMV, VEB o AdV así como los principales parámetros biológicos que lo modulan. Bloque III. Analizar el papel de los polimorfismos genéticos y de la técnica de NGS en la modulación de la respuesta inmunológica específica de virus post-TPH. Su diseño metodológico es el siguiente: Bloque I: estudio unicéntrico prospectivo en el que se incluyeron 23 sujetos sanos de la Comunidad Foral de Navarra. Bloque II: estudio multicéntrico prospectivo en el que se incluyeron 50 pacientes que fueron sometidos entre los años 2017-2019 a un alo-TPH en el Servicio de Hematología y Hemoterapia del Complejo Hospitalario de Navarra (CHN) y en el Servicio de Hematología y Hemoterapia del Hospital General Universitario Gregorio Marañón (HGUGM). Bloque III: estudio unicéntrico retrospectivo en el que se incluyeron de manera consecutiva 90 parejas donante/receptor. Estos últimos habían sido sometidos a un alo-TPH en el HGUGM durante el periodo comprendido entre los años 2000-2015.
From Medicalizing State to Sacralizing Status of Thai Buddhist Monks in Secular Space: A Case Study of the Priest Hospital
Authors: Buaban Jesada
Published: November 2021

This paper examines the sacred status of Thai Buddhist monks who have been engaging with the modern secular healthcare system, which also contrasts with their monastic traditions. It questions how modern medication has affected the sacred figure of Thai monks and what is their reaction to maintain their sacred status in such a secular space? Participant observations and informal interviews have been conducted, and data are conceptualized through the ideas of the birth of the clinic and biopower proposed by Michel Foucault. It finds that the traditional healing previously played by Thai monks has been challenged by modern medication eventually the monks also access the modern hospital. This phenomenon helps to change the idea of the cause of sickness, from demons to germs. This is interesting when some Buddhists request the monastic code-based healthcare system and monk patients’ zone. This paper argues that such an effort aims to maintain the sacred status of monks, who are perceived as holy persons and should not be seen by laypeople especially when they are in sickness, pain, and sorrow, which portray their ordinary human natures. Therefore, zoning management in the government hospital is needed to sacralize the monks’ status.
The School Administration Affecting the Life Skill and Career of Students in the Opportunity Expansion School, Narathiwat Province, Thailand
Authors: Ama Maromlee , Sirisuk Kanokkorn
Published: November 2021

This study was aimed to study the school administration that influenced the promotion of life skills and career of students of Educational Opportunity Expansion Schools in Narathiwat Province. The samples were 200 teachers who served as heads of four divisions in Educational Opportunity Expansion Schools in Narathiwat Province, chosen through the purposive sampling technique. Research tools were five-scale questionnaires with reliability of 0.952. Statistics used for this research include percentage, mean, standard deviation, and stepwise multiple regression analysis. It was found that administrative performance and the promotion of life skills and career of students were at the high level, both overall and each aspect. School administrators’ administrative performance that affects students’ life skills and career of Educational Opportunity Expansion Schools in Narathiwat Province consisted of three variables; coordination and network building, assessment and evaluation, and development and encouragement. The multiple regression analysis values were 0.803, and the prediction discrepancy value was 0.153, which could predict the promotion of life skills and career of students of Educational Opportunity Expansion Schools in Narathiwat Province as high as possible 64.5 percent.