bluuebunny/crossref_metadata_2025 huggingface dataset:
Kolabolasi Bidan dan Kader Posyandu dalam Peningkatan Kuantitas Tidur Bayi melalui Baby Massase di Posyandu Melati Kelurahan Blimbing Kecamatan Paciran Lamongan
Authors: Khairoh Miftahul , Ummah Kholifatul
Published: January 2023

Masa  bayi  merupakan  masa  emas untuk pertumbuhan   dan   perkembangan  anak sehingga perlu mendapatkan perhatian  khusus Salah  satu  faktor  yang  mempengaruhi    tumbuh    kembang    bayi  adalah  tidur  dan  istirahat. (Endah, 2019). Metode    ini diberikan  pada  satu  kelompok saja  tanpa kelompok    pembanding.Penelitian    ini bertujuan untuk mengetahui kuantitas tidur bayi  sebelum dan  sesudah  dilakukan pijat yang dilaksanakan oleh kader posyandu. Berdasarkan tabel 1 diketahui kuantitas tidur bayi sebelum dilakukan pemijatan yaitu minimum 12 jam sebanyak 13 orang (43,3%)    dan    maximum    15    jam sebanyak  14    orang  (46,7%).  Hal ini  berarti  bahwa  bayi  mengalami kuantitas tidur buruk karena maksimum   tidur   bayi usia 3-6 bulan hanya   12-14 jam. Kualitas  tidur  bayi  dikatakan  kurang jika  bayi  mengalami  gangguan tidur  jika pada  malam  hari  tidurnya  kurang  dari  16 jam,  terbangun  lebih  dari  3  kali  dan lama terbangunnya  lebih  dari  1  jam.  Selama tidur  bayi  terlihat  selalu  rewel,  menangis dan sulit tidur kembali (Dahlia, 2022).
Faktor-Faktor yang Berpengaruh pada Gangguan Pemenuhan Istirahat Tidur Ibu Nifas
Authors: Hamang Sitti Hadriyanti , Nurhayati Nurhayati
Published: January 2023

Istirahat yang cukup bagi ibu yang baru melahirkan salah satu masalah yang penting untuk diperhatikan walaupun tidak mudah untuk mencapainya, Dari hasil Survei Demografi dan kesehatan indonesia (SDKI)  menyebutkan bahwa  sekitar 460/100.000 kelahiran hidup terdapat ibu yang mengalami gangguan istirahat tidur (Depkes RI, 2007). Penelitian ini dilaksanakan dengan tujuan diketahuinya faktor yang berhubungan dengan gangguan pemenuhan kebutuhan istirahat tidur  ibu nifas  di RSKDIA Siti Fatimah Makassar 2015. Jenis penelitian ini adalah penelitian  non experiment dengan menggunakan desain survei analitik dengan pendekatan cross sectional yaitu dimana peneliti melakukan pengukuran variabel dependen dan independen pada saat yang bersamaan, yang tujuannya adalah untuk mendapatkan gambaran yang jelas tentang faktor-faktor gangguan pemenuhan kebutuhan istirahat tidur pada ibu nifas. Populasi dalam penelitian ini adalah semua ibu postpartum yang dirawat di ruang Nifas RSKDIA Siti Fatimah Makassar. Teknik pengambilan sampel yaitu non probability dengan teknik purposive sampling yaitu menetapan sampel dengan cara memilih sampel diantara populasi sesuai yang dikehendaki peneliti sehingga sampel tersebut dapat mewakili karakteristik populasi berdasarkan kriteria inklusi yang telah ditetapkan. jumlah sampel sebanyak 52 orang. Berdasarkan hasil penelitian dari hasil uji Chi-Square diperoleh bahwa Ada hubungan antara nyeri nifas dengan gangguan pemenuhan istirahat tidur ibu nifas di RSKDIA Siti Fatimah Makassar dengan nilai  p= 0,008 (p<?= 0,05). Ada hubungan antara kecemasan dengan gangguan pemenuhan istirahat tidur ibu nifas di RSKDIA Siti Fatimah Makassar dengan nilai  p= 0,010 (p<?= 0,05). Ada hubungan antara peran ibu baru dengan gangguan pemenuhan istirahat tidur ibu nifas di RSKDIA Siti Fatimah Makassar dengan nilai  p= 0,018 (p<?= 0,05). Saran dalam penelitian ini adalah bagi ibu nifas sebaiknya dapat mengetahui  tentang gangguan pemenuhan istirahat tidur ibu post partum  dan lebih maksimal mempersiapkan diri menjadi seorang ibu sehingga tidak terjadi gangguan pada pemenuhan istirahat tidur. Untuk nyeri nifas dan kecemasan ibu nifas diharapkan  para petugas kesehatan dapat memberikan penyuluhan cara mengurai nyeri dengan teknik relaksasi, masase, distraksi, dan informasi cara merawat diri dan bayi.
The effect of picture and picture learning model on learning outcomes of junior high school madani makassar students
Authors: Yusal Muh Sri , Bahar Irnayanti , Namul Bernadina
Published: January 2023

The picture and picture learning model is a learning strategy through the use of image media as learning media which are paired and sequenced logically. This learning model involves students to participate in learning activities that are innovative, creative, and fun. In addition, the picture and picture learning model is to organize the learning experience so that it can be used as a reference or guide for learning designers and teachers in planning teaching and learning activities. This research is an experimental and non PTK research. The data from this study were analyzed through descriptive statistical analysis and independent T-test which were first carried out by the process of normalization and homogenization of data. This study aims to examine the effect of the picture and picture learning model in improving learning outcomes at Madani Junior High School Makassar. The results showed that the picture and picture learning model had a significant influence on the learning outcomes of class VII Junior High School Madani Makassar. This learning model has proven to be effective in providing opportunities for students to work together with fellow students through structured, group tasks, so that open interactions and effective interdependence relationships occur among various group members.
Analysis of leaf cellulose gayam (inocarpus vagiver) based on different altitudes
Authors: Smith Alwi , Erubun Adelheid Adonia , Arini Ine
Published: January 2023

Gayam (Inocarpus vagiver) contains natural chemicals in the form of primary metabolites that play an important role in plant survival. The primary metabolites are directly involved in the growth of the Gayam plant. Cellulose is the main component of plant cell walls .Cellulose is a natural material that can be renewed and its uses are very broad. This is because cellulose is widely used for the manufacture of paper and products with various properties. The purpose of this study was to determine the cellulose content of the leaves of the Gayam plant based on different altitudes. The method used in this research is descriptive quantitative and qualitative with the sampling technique using purposive sampling. Based on the iodine test, Gayam leaves in Ema vilage and Airlouw both have cellulose compounds. The average cellulose content in Ema vilage is 0.23315% while Airlouw is 0.20008% which means the higher cellulose content is in Ema.
The effect of light on the early growth wheat (Triticum aestivum L)
Authors: Destiana Novia , Nuryandani Einstivina , Handayani Sri Kurniati , Diki Diki
Published: January 2023

Triticum aestivum L is a cereal plant that grows optimally in a subtropical climate. In tropical climate wheat growth experieces various obstacles such as high air temperature and humidity, and intensity of light. Study of wheat conditions for the growth of this plant in tropical areas such as Indonesia is needed. This study aims to determine the effect of light on the germination, growth, and early development of wheat.this is an experimental research with two treatments, the first group was in normal light and the the second was without light. Each treatment was carried out using 30 replications. The analysis was carried out by comparing the average value of plant length and plant morphology from eight days of observation on two kinds of treatments. The results showed that there were differences in plant height in the two treatments. The average plant height on the 8th day in normal light treatment was 9.76 cm, while the average plant height with the treatment without light was 10.1 cm. Observations of growth on the morphology of wheat plants showed that plants with no light treatment experienced a slowdown in the opening of the second leaf, had a paler color and thinner leaf blades, compared to plants grown with light treatment. The absence of light accelerates the germination process and increases the height of wheat plants, but at a later stage it can slow down the development of these plants.
Inhibition of methanol extract snail gonggong (Strombus urturella) to pathogenic bacteria Vibrio alginolyticus
Authors: Selfanay Frans , Wael Syahran , Watuguly Theopilus Wilhelmus
Published: January 2023

The purpose of this study was to determine the methanol extract of snail gonggong (Strombus turturella) and the inhibition of methanol extract of gonggong snail meat (Strombus turturella) against the pathogenic bacterium Vibrio alginolyticus. The study used a completely randomized design. The treatment was giving the extract of snail gonggong meat with concentration of 100%, 50%, 25%, positive control using amoxcillin and negative control using distilled water with three replications. The identification of bioactive compounds included alkaloids, saponins, flavonoids, steroids and triterpenoids. The antibacterial activity of the methanol extract of snail gonggong meat (Strombus turturella) was tested by the diffusion method at concentrations of 100%, 50% and 25%. The data collected is then analyzed descriptively qualitatively. The results showed that the antibacterial activity of the 100% concentration of the methanol extract of the gonggong snail meat had moderate inhibition against Vibrio alginolyticus (diameter 7,833 mm). while the concentrations of 50% and 25% did not have an inhibition zone. The identified bioactive compounds included alkaloids, saponins, flavonoids and steroids, while the terpenoid and phenolic compounds were not identified. Thus, the methanol extract of gonggong snail meat has antibacterial potential that can be used to overcome the attack of pathogenic bacteria.
An Analysis of Figurative Languages Used in Lokamase Ceremony
Authors: Yanto Yanto , Siga Rikardus Nong
Published: January 2023

The use of language in human life is very diverse, one of which is figurative language. Figurative language is the use of beautiful words with figurative language created from the author's feelings to give effect by comparing one thing with another object that is more general. The objectives of the study are to describe the types of the figurative language found in Lokamase Ceremony to identify the contextual meaning of the figurative language. This research is a qualitative research method. The method used in collecting the data related to the subject of this research is observation, interviews and documentation method. This study was conducted by collecting any relevant data and information about the topic or problem of the study from head of Lokamase and journal that are available for the analysis. The data collection used the following steps: collecting, reduction, display, and drawing conclusion and then selecting the data that used the types of figurative language. While the steps to analyze the data are identifying the types of figurative language, identifying the contextual meaning of the figurative language, and the last is interpreting the data. The result shows that found simile and hyperbole types of figurative language used in Lokamase ceremony and have their own meaning. Summing up the overall language of the figurative meanings used in the lokamase traditional ceremony is to uphold self-respect, human rights and also maintain indigenous culture.
Improving Students’ Reading Comprehension of Narrative Text Through Directed Reading-Thinking Activity Strategy
Authors: Fawahid Ahmad , Yuliana Y Gatot Sutapa , Suhartono Luwandi
Published: January 2023

This study aim was to find out how directed reading-thinking activity strategy could improve students’ reading comprehension of narrative text. The directed reading-thinking activity strategy was applied to teach the ninth grade students of SMPS Awaluddin in the academic year of 2021/2022. This study was a classroom action research. The research findings showed that the students paid attention to the teacher’s explanation, the students were very active and brave to ask the teacher, looked enthusiastic and understood the reading comprehension of narrative text through directed reading-thinking activity strategy. It also was proven by the students’ individual reading test, in which their scores got increase because many students’ individual score got 72 until 84 which included good category, and two students got 88 until 92 as excellent category. Therefore, it can be concluded that directed reading- thinking activity strategy successfully improved the students’ reading comprehension of narrative text. The researcher hopes this strategy is used by the teachers in teaching reading comprehension.
Efektifitas Ekstrak Lidah Mertua (Sansevieria trifasciata var laurentii) Sebagai Antifungi Candida albicans
Authors: Paramastri Prasasti Kusumaning , Qurrohman Muhammad Taufiq
Published: January 2023

Candidiasis is a disease caused by Candida albicans, this disease has a mortality rate of > 25%, mainly affecting adults, with a frequency of women 2 - 3 times more than men (Raningsih et al., 2018). A commonly used fungi drug is ketoconazole. but it has many side effects so it is necessary to find for alternatives to natural ingredients, namely the leaf of lidah mertua (Sansevieria trifasciata var laurentii) because it contains compounds saponins, flavonoids, triterpenoids, and steroids as antifungals The leaf of lidah mertua were extracted by maceration technique. The purpose of this research was to determine the effect of antifungi of ethanol extract the leaf of Lidah Mertua (Sansiviera trifasciata var Laurentii) against the fungus Candida albicans. This research was experimental using the disc diffusion method with a spread plate technique in the inhibition zone formed at concentrations of 25%, 20%, 15%, 10%, 5%, positive control and negative control. The results of the One way Anova test is known that differ significantly. From the results of this research, it can be concluded that the ethanol extract of the leaves of the leaf of lidah mertua (Sansevieria trifasciata var laurentii) has an effect on the antifungal activity of Candida albicans Keywords       : Candida albicans, Leaf of Lidah Mertua, Antifungal, Ketokonazole
Problem Solving Tipe SSCS Berbantuan Schoology: Upaya Meningkatkan Berpikir Kritis Matematis
Authors: Sugiarni Rani , Durri Royya Fawazi
Published: January 2023

Penelitian ini bertujuan untuk mengetahui lebih jauh tentang bagaimana meningkatkan kemampuan berpikir kritis siswa menggunakan model pembelajaran Problem Solving tipe SSCS berbantuan Schoology. Quasi Expetimental dipilih sebagai metode pada penelitian ini dengan mengadopsi desain Nonequivalent Control Group Design. Dalam penelitian ini, Siswa X MAN 2 Cianjur dipilih sebagai populasi, sedangkan siswa X IPS 3 dan X IPS 4 sebagai sampel. Uji pada penelitian ini menggunakan uji banding dan uji gain. Hasil penelitian diperoleh temuan bahwa siswa yang menggunakan model pembelajaran Problem Solving tipe SSCS berbantuan Schoology lebih baik dari segi rata-rata kelas dan mampu meningkatkan kemampuan berpikir kritis siswa sebesar 30,35%.This study aims to find out more about how to improve students' critical thinking skills using the Schoology-assisted SSCS-type problem-solving learning model. Quasi-experimental design was chosen as the method in this study by adopting the nonequivalent control group design. In this study, students X MAN 2 Cianjur were selected as the population, and students X IPS 3 and X IPS 4 were selected as samples. In this study, comparative and gain tests were used. The results of the study found that those using the Schoology-assisted SSCS-type problem-solving student learning model were better in terms of the class average and were able to improve students' critical thinking skills by 30.35%.
Pengembangan Media Pembelajaran Matematika Electronic Snake and Ladder Pada Game-Based Learning
Authors: Syaikhu Arif Achmad , Pranyata Yuniar Ika Putri , Fayeldi Trija
Published: January 2023

Penelitian ini merupakan penelitian pengembangan media pembelajaran matematika Electronic Snake and Ladder (eSnL) pada game-based learning untuk meningkatkan motivasi belajar di SMP Modern Al Rifa Ie. Penelitian ini bertujuan untuk mengetahui pengembangan game edukasi dan mengetahui kelayakan game edukasi. Penelitian ini menerapkan pendekatan Research & Development dengan menggunakan model ADDIE yang dimulai dari tahap (1) analisis; (2) desain; (3) pengembangan; (4) implementasi; dan (5) evaluasi. Hasil uji kelayakan game edukasi matematika Snake and Ladder dinyatakan sangat valid berdasarkan hasil validasi oleh ahli media dengan persentase kevalidan sebesar 88,90%, ahli materi sebesar 81,25%, dan ahli pembelajaran sebesar 86,80%, dinyatakan sangat praktis berdasarkan hasil angket respon siswa dengan persentase sebesar 97,26%, dan terbukti efektif dalam meningkatkan motivasi belajar siswa berdasarkan selisih hasil angket motivasi belajar siswa sebelum menggunakan media dari 76,38% menjadi 85,78% setelah menggunakan media. Hal tersebut menunjukkan produk pengembangan media pembelajaran matematika Electronic Snake and Ladder (eSnL) pada game-based learning valid, praktis dan efektif untuk meningkatkan motivasi belajar siswa SMP Modern Al Rifa Ie.
This research is a research on the development of Electronic Snake and Ladder (eSnL) mathematics learning media on game-based learning to increase motivation to study at Al Rifa Ie Modern Junior High School. This study aims to determine the development of educational games and determine the feasibility of educational games. This research applies the Research & Development approach using the ADDIE model which starts from stage (1) analysis; (2) design; (3) development; (4) implementation; and (5) evaluation. The feasibility test results of the Snake and Ladder mathematics educational game were declared very valid based on the validation results by media experts with a percentage of validity of 88.90%, material experts of 81.25%, and learning experts of 86.80%, it was stated to be very practical based on the results of student response questionnaires with a percentage of 97.26%, and proven effective in increasing students' learning motivation based on the difference in the results of the student learning motivation questionnaire before using the media from 76.38% to 85.78% after using the media. This shows that the electronic snake and ladder (eSnL) mathematics learning media development product on game-based learning is valid, practical and effective to increase the learning motivation of students of Al Rifa Ie Modern Junior High School.
Safety profile of thiazole derivative and its complex with PEG-based polymeric nanoparticles on liver and blood cells in tumor-bearing mice
Authors:   Ivan Franko National University of Lviv, Ukraine, Ilkiv M. V. , Shalai Ya. R. ,   Ivan Franko National University of Lviv, Ukraine, Ostapiuk Yu. V. ,   Ivan Franko National University of Lviv, Ukraine, Mitina N. E. ,   Lviv Polytechnic National University, Ukraine, Zaichenko O. S. ,   Lviv Polytechnic National University, Ukraine, Babsky A. M. ,   Ivan Franko National University of Lviv, Ukraine
Published: January 2023

Background. Drug delivery systems (DDS) have demonstrated a significant ability to overcome many of the challenges associated with the delivery of hydrophobic chemotherapeutic compounds to tumor tissues. However, hepatotoxicity and suppression of the hematopoietic system are the key problems in the clinical treatment of cancer by nanoparticle-based DDS that can limit their medical exposure. The aim of this work was to investigate the effect of thiazole derivative N-(5-benzyl-1,3-thiazol-2-yl)-3,5-dimethyl-1-benzofuran-2-carboxamide (BF1) conjugated with PEG-based polymeric nanoparticles (PEG-PN – Th1) on the hepatocytes and blood hematological parameters of mice with grafted NK/Ly. Materials and Methods. The experiments were conducted on white wild-type male mice with grafted NK/Ly lymphoma. Investigated compounds BF1, PEG-PN Th1, and combination of PEG-PN + BF1 (Th2) at a final concentration of 10 μM were added to the liver samples and incubated for 10 minutes. The level of lipid peroxidation products and the level of antioxidant defense system (AOS) enzymes were determined according to the techniques described below. The cytological parameters of blood were investigated after the treatment of mice with BF1 in concentrations of 10 and 20 mg/kg, PEG-PN (20 mg/kg) and Th2 complex (10 mg/kg). On the 14th day of the experiment, blood was taken from all groups and the number of erythrocytes, leukocytes and leukocyte formula were counted. Results. It was reported that neither BF1, PEG-PN, nor their complex Th2 changed the content of lipid peroxidation products or the level of AOS enzymes in hepatocytes from mice with NK/Ly. BF1 (in concentration 10 mg/kg) and PEG-PN + BF1 complex did not change the level of murine erythrocytes compared to Doxorubicin. All investigated compounds, except free PEG-PN, significantly decreased the NK/Ly-triggered leukocytosis and increased the level of small lymphocytes. The NK/Ly lymphoma development led to an increase in the number of neutrophils, while BF1 and its complex with PEG-PN reduced it significantly. Conclusions. BF1 and PEG-PN + BF1 complex had limited negative side effects in the mice with NK/Ly. The investigated compounds were not hepatotoxic toward murine liver cells. Both BF1 and its complex with PEG-PN did not cause any major side effects on the murine blood cells.
Embodiment experience in some orientational metaphors in English and Vietnamese newspapers
Authors: Huynh Huynh Ngoc Mai Kha , Nguyen Nguyen Hoang Thuc Anh
Published: January 2023

The article aims to investigate the impact of embodiment theory by Lakoff & Johnson on some orientational metaphorical structures identified through the examining of some official electronic newspapers in the UK and Vietnam. Based on the data collected via the use of Metaphor Identification Procedure by Kovecses, the article has made an illumination over the operation and determination of embodied experiential principles on human’s mind, which sets foundation for mankind’s conceptualization about the world through their interactive experience with their surrounding environment. Based on acquired explanations about embodiment experience, the article has proposed some initial conclusions about embodiment in metaphorical expressions which include both universality and peculiarity in language & culture of a nation.
Insights from fund management companies in Vietnam: Evidence from financial reports
Authors: Nguyen Nguyen Quang Minh Nhi
Published: January 2023

This paper provides new evidence on fund industry in Vietnam, specifically the profitability and firm characteristics of a company which manages funds. Using hand-collected company information for fund management companies (FMCs), the study shows that FMCs generated a high growth in profitability and revenue from 2014 to 2020. The paper also contributes to the fund management literature by explaining cross-sectional variation in profitability. The research finds that size is the key determinant of FMCs’ profitability, where larger FMCs generate significantly higher profitability. In addition, Vietnamese FMCs have a very high liquidity ratio, a low proportion of fixed assets and a small debt ratio.
Seismic response and damage evaluation for anchored and unanchored cylindrical above ground steel tanks
Authors: Phan Phan Hoang Nam , Nguyen Nguyen Hoang Vinh , Hoang Hoang Phuong Hoa
Published: January 2023

This paper aims to first present a review of studies on numerical modeling and seismic response analysis of above ground steel liquid storage tanks. On that basis, a procedure for estimating dynamic parameters associated with simplified models for anchored and unanchored conditions together with calculation methods of seismic responses and damage states of tanks are presented. In which, the nonlinear behavior of the bottom plate in the case of unanchored conditions caused by sliding and uplift phenomena is properly modeled based on the nonlinear static pushover analysis on a 3D finite element model. Finally, an example of the numerical modeling and seismic response analysis of a water tank is presented. The seismic responses and damage of both anchored and unanchored conditions are compared and evaluated in detail.
Debunking the myths of historiography. Russians and Romanians at the capture of Rahovo (November 9, 1877)
Authors:   Institute of Slavic Studies, Russian Academy of Sciences, Frolova Marina
Published: January 2023

The capture of the town of Rahovo in Bulgaria (now Oryahovo) on November 9, 1877 does not belong to the significant events of the Russo-Turkish War of 1877–1878, but in the history of Romania, where this war is treated as a war for independence, it is interpreted as “an important moment of the operation to encircle the Plevna Ottoman grouping” and is on a par with the capture of Grivitsky redoubt No. 1 on August 30, 1877. There is a widespread claim in historiography that the Romanian detachment stormed Rahovo. The study of published documents, primarily the multi-volume “Collection of Materials on the Russo-Turkish War of 1877–1878 on the Balkan Peninsula”, as well as the diaries of Russian officers who participated in this war, allows us to show how factual errors and historical myths arise. The article shows that the Russian-Romanian detachment solved a tactical problem — Rahovo was liberated from the Turks, and a Romanian garrison was located in it. But the fortifications and the city were not taken during the fight, the Romanian troops could not defeat the Turks in battle, and entered Rahovo only after the Turkish garrison had left it. The statements about the storming of Rahovo as well as Grivitsky redoubt No. 1 by Romanians refer to the same hoax, deliberately created in 1877 for the glory and growth of popularity of Prince Charles in Romania, to strengthen the authority of his dynasty.
Folk demonology of Podlasie (based on own materials)
Authors:   Institute of Slavic Studies, Russian Academy of Sciences, Gura Aleksander
Published: January 2023

The article publishes field material on the folk demonology of Podlasie, collected by the author in 1990, 1993, and 2017. Mythological characters are described with functions typical for the spirits of the house and barn: weasel as the patron of cattle, “zmora”, braiding the mane of horses and strangling the sleeping ones. The brownie demon-enricher has a number of similarities with the West Slavic flying fiery serpent. The territory of Podlasie is the western periphery of the East Slavic distribution area of rusalky and the southern periphery of the distribution area of Lithuanian “laumė” (“loima” in Podlasie). Rusalky, in addition to their typical properties (appearance in a rye field etc.), sometimes combine the signs of other characters – they mix with Lady Midday, with weasel, sirens (half-maiden-half-fish), are identified with the grasshopper and flashing lights. The demon that makes a person go astray is known as “blud”, which is characteristic of this character in the folk tradition of Western Ukrainians, Poles and other Western Slavs. The water spirit (“vodyanoy”) is almost unknown, it was mainly used to frighten only children. Many beliefs are associated with death and the souls of the dead: the souls of unbaptized children, the walking dead (vampire), the image of death. Tales and beliefs about witches and sorcerers are widespread, especially stories about stealing milk from other people’s cows. Beliefs about werewolfes, double-hearted aliens, sorcerers who drive away clouds and a single mention of a cloud-ruler demon are recorded. The devil appears both in the anthropomorphic form of a gentleman in a black hat, and in the zoomorphic form of a dog or a black ram. Some characters are found only in verbal formulas that are used to scare children.
Incomprehensible literature, suspicious plays, and omnipotent censorship: On the issue of ideological contradictions in Polish-Soviet cultural contacts at the turn of the 1920s–1930s
Authors:   Lomonosov Moscow State University, Semakina Tatiana
Published: January 2023

During the interwar period, the role of soft power politics in interstate relations increased, it included the expansion of cultural influence and the promotion of cultural achievements abroad. In the USSR, within the framework of this policy, in 1925, the All-Union Society for Cultural Relations with Foreign Countries was established. The newly independent Polish state was among the countries with which it was necessary to expand cultural contacts, but there were many factors that hindered the development of this process, although there are many examples of successful interaction. In particular, there were many ideological contradictions between the Soviet Union, which aspired to communism, and where socialist realism was actively developing as a new method in culture and art in the 1930s, and the Second Polish Republic, where J. Piłsudski established an authoritarian regime and where anti-Soviet sentiments were strong. These contradictions manifested themselves in almost all spheres of cultural cooperation: in the field of cinematography, theatrical art, literature, etc. Despite best efforts of All-Union Society for Cultural Relations with Foreign Countries, many of them remained unresolved. Based on archival and journalistic sources, this article examines the role of ideological differences in the development of bilateral Polish-Soviet contacts in the field of culture.
KAJIAN ASPEK SDM PERUSAHAAN, DAMPAK SOSIAL DAN EKONOMI MASYARAKAT DALAM MENUNJANG KEBERLANJUTAN PABRIK KELAPA SAWIT (PT. DDP LUBUK BENTO MUKOMUKO)
Authors: Dhita Auliya Rahma , Uker Damres , Marsigit Wuri
Published: January 2023

Penelitian ini bertujuan untuk mengetahui keberlanjutan pabrik kelapa sawit berdasarkan aspek sumber daya manusia  perusahaan, dampak sosial dan ekonomi masyarakat sekitar lokasi. Penelitian ini mengunakan teknik trigulasi mengabungkan pengumpulan data primer dan sekunder. Dalam penelitian ini mengunakan random sampling . Hasil penelitian ini PT. Darian Dharma Pratama Lubuk Bento Aspek SDM perusahaan strategi yang dilakukan dengan menerapkan SOP serta perusahaan memberikan pelatihan dan pengembangan pada karyawan. Dampak sosial perusahaan memberikan CSR kepada masyarakat dan dampak ekonomi masyarakat perusahaan memberikan peluang pekerjaan dan perubahan taraf kehidupan masyarakat. Maka dari itu PT. Darian Dharma Pratama dapat dikatakan keberlanjutan hal ini SDM terealisasi, dampak sosial dan ekonomi masyarakat teratasi serta mensejahterakan masyarakat sekitrnya.
Differential expression of DUSP26 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: January 2023

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines ALS using published data (3, 4). We found significant differential expression of DUSP26, encoding dual specificity phosphatase 26, in the skeletal muscle of patients with ALS. DUSP26 was also differentially expressed in primary lower motor neurons isolated from patients with ALS. DUSP26 transcript was present at significantly lower levels in ALS patient skeletal muscle as compared to control motor neurons. These analyses will begin to define the transcriptional landscape of ALS.
Measuring psychiatric symptoms online: A systematic review of the use of inventories on Amazon Mechanical Turk (mTurk)
Authors: Kolc Kristy L. , Tan Yue Xuan Karen , Lo Alys Zuk Yu , Shvetcov Artur , Mitchell Philip , Perkes Iain
Published: January 2023

Symptom measurement in psychiatric research increasingly uses digitized self-report inventories and is turning to crowdsourcing platforms for recruitment, e.g., Amazon Mechanical Turk (mTurk). The impact of digitizing pencil-and-paper inventories on the psychometric properties is underexplored. Against this background, numerous studies report high prevalence estimates of psychiatric symptoms in mTurk samples. Here we develop a framework to evaluate the online implementation of psychiatric symptom inventories relative to two domains, that is, the adherence to (i) validated scoring and (ii) standardized administration. We apply this new framework to the online use of the Patient Health Questionnaire (PHQ-9), Generalised Anxiety Disorder-7 (GAD-7), and Alcohol Use Disorder Identification Test (AUDIT). Our systematic review of the literature identified 36 implementations of these three inventories on mTurk across 27 publications. We also evaluated methodological approaches to enhance data quality, e.g., the use of bot detection and attention check items. Of the 36 implementations, 23 reported the applied diagnostic scoring criteria and only 18 reported the specified symptom timeframe. None of the 36 implementations reported adaptations made in their digitization of the inventories. While recent reports attribute higher rates of mood, anxiety, and alcohol use disorders on mTurk to data quality, our findings indicate that this inflation may also relate to the assessment methods. We provide recommendations to enhance both data quality and fidelity to validated administration and scoring methods.
Proprioceptive uncertainty promotes the rubber hand illusion
Authors: Chancel Marie , Ehrsson H. Henrik
Published: January 2023

Vision, touch, and proprioception contribute to body ownership, i.e., the multisensory perception of limbs and body parts as one’s own. Recently, the emergence of body ownership illusions such as the visuo-tactile rubber hand illusion has been quantitatively described by Bayesian causal inference models in which the observer computes the probability that visual and tactile signals come from a common source. Given the importance of proprioception for the perception of one’s own body, we hypothesized that proprioceptive information and its relative reliability also impact this inferential process. We used a detection-like task based on the rubber hand illusion paradigm where participants were asked to report whether the rubber hand felt like their own (illusion) or not. We systematically manipulated the degree of asynchrony of visual and tactile stimuli delivered to the rubber hand and the hidden real hand under two different levels of proprioceptive noise achieved by delivering low-frequency muscle vibration (20 Hz) to the lower arm’s antagonist extensor and flexor muscles (biceps and triceps). As hypothesized, we found that the probability of the emergence of the rubber hand illusion increased with proprioceptive noise. Moreover, fitting the data to a Bayesian causal inference model of body ownership revealed that the influence of proprioceptive uncertainty on the emergence of the illusion was captured by a change in the a priori probability of a common cause for vision and touch. Collectively, these results offer new insights into how proprioceptive uncertainty determines the rubber hand illusion and the multisensory perception of one’s own body.
Differential expression of SLC19A2 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: January 2023

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines sporadic ALS using published data (3, 4). We found significant differential expression of SLC19A2, encoding solute carrier family 19 member 2, in the skeletal muscle of patients with ALS. SLC19A2 was also differentially expressed in fibroblasts isolated from patients with ALS. SLC19A2 transcript was present at significantly lower levels in ALS patient skeletal muscle as compared to control skeletal muscle. These analyses will begin to define the transcriptional landscape of ALS.
Pharmacokinetic and Pharmacodynamic Interaction of the Ayahuasca Constituents Harmine and Dimethyltryptamine (DMT) in the Rat Brain
Authors: Egger Klemens , Gudmundsen Frederik , Jessen Naja Støckel , Baun Christina , Pötzsch Sandra , Shalgunov Vladimir , Herth Matthias M. , Quednow Boris B. , Martin-Soelch Chantal , Dornbierer Dario , Scheidegger Milan , Cumming Paul , Palner Mikael
Published: January 2023

RationaleThe psychedelic effects of the traditional Amazonian botanical decoction known as ayahuasca are attributed to the effects of N,N-dimethyltryptamine (DMT) at brain serotonin 5-HT2A receptors. To make oral DMT bioavailable, ayahuasca additionally contains reversible monoamine oxidase A (MAO-A) inhibitors, namely β-carboline alkaloids such as harmine. However, there is lacking biochemical evidence to substantiate this pharmacokinetic potentiation in the brain. ObjectivesTherefore, we measured the pharmacokinetic profile of harmine and DMT in the rat brain. Additionally, we investigated the pharmacodynamic properties of DMT and/or harmine. MethodsWe first measured brain concentrations of harmine and DMT after treatment with harmine and/or DMT at low doses (1 mg/kg each) or harmine plus DMT at moderate doses (3 mg/kg each). In the same groups of rats, we also measured ex vivo the effects of these treatments on the availability of serotonin 5-HT2A receptors in frontal cortex. Finally, we explored influences of DMT and/or harmine in the lower dose group on brain glucose metabolism with [18F]FDG-PET. ResultsResults confirmed that co-administration of harmine inhibited the formation of the DMT metabolite indole-3-acetic acid (3-IAA) in the brain, while increasing the cerebral availability of DMT. However, we were unable to detect any significant occupancy by DMT at 5-HT2A receptors measured ex vivo, despite brain DMT concentrations as high as 11.3 µM at moderate doses. We did not observe strong influences of low dose DMT and/or harmine on [18F]FDG-PET. ConclusionsThe present preliminary results call for further experiments to establish the dose-dependent effects of harmine/DMT on receptor occupancy and on cerebral metabolism.
Differential expression of ISOC1 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: January 2023

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines ALS using published microarray data (3, 4). We found significant differential expression of ISOC1, encoding isochorismatase domain-containing 1, in the skeletal muscle of patients with ALS. ISOC1 was also differentially expressed in primary motor neurons isolated from patients with ALS. ISOC1 transcript was present at significantly higher levels in skeletal muscle from patients with ALS as compared to skeletal muscle from control individuals. These analyses will begin to define the transcriptional landscape of ALS.
Global Illumination for Fun and Profit—VGTC Journal Template
Authors: Carberry Josiah S. , Grimley Ed , Stewart Martha
Published: January 2023

This serves as an example for a preprint on OSF using the VGTC journal template.
Differential expression of RALGPS2 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: January 2023

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines ALS using published data (3, 4). We found significant differential expression of RALGPS2, encoding Ral GEF with PH domain and SH3-binding motif 2, in the skeletal muscle of patients with ALS. RALGPS2 was also differentially expressed in the induced pluripotent stem cell (iPSC)-derived motor neurons of patients with ALS. RALGPS2 transcript was present at significantly higher levels in ALS patient skeletal muscle as compared to control skeletal muscle. These analyses will begin to define the transcriptional landscape of ALS.
Differential expression of PCDHB13 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: January 2023

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines ALS using published data (3, 4). We found significant differential expression of PCDHB13, encoding protocadherin beta 13, in the skeletal muscle of patients with ALS. PCDHB13 was also differentially expressed in fibroblasts isolated from patients with ALS. PCDHB13 transcript was present at significantly higher levels in ALS patient skeletal muscle as compared to control skeletal muscle. These analyses will begin to define the transcriptional landscape of ALS.
Differential expression of TYRP1 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: January 2023

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines ALS using published microarray data (3, 4). We found significant differential expression of TYRP1, encoding tyrosinase-related protein 1, in the skeletal muscle of patients with ALS. TYRP1 was also differentially expressed in primary motor neurons isolated from patients with ALS. TYRP1 transcript was present at significantly lower levels in skeletal muscle from patients with ALS as compared to skeletal muscle from control individuals. These analyses will begin to define the transcriptional landscape of ALS.
Differential expression of THBS4 in amyotrophic lateral sclerosis.
Authors: Mamoor Shahan
Published: January 2023

Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines ALS using published and public data (3, 4). We found significant differential expression of THBS4, encoding thrombospondin 4, in the skeletal muscle of patients with ALS. THBS4 was also differentially expressed in the induced pluripotent stem cell (iPSC)-derived motor neurons of patients with ALS. THBS4 transcript was present at significantly higher levels in ALS patient skeletal muscle as compared to control skeletal muscle. These analyses will begin to define the transcriptional landscape of ALS.
The Prospective Association Between the Use of E-Cigarettes and Other Psychoactive Substances in Young People: A Systematic Review and Meta-Analysis
Authors: Lau Lucinda , Conti Aldo Alberto , Hemmati Zeynab , Baldacchino Alexander
Published: January 2023

The use of electronic cigarettes by young people has increased exponentially in the past decade due to various health and social influences. E-cigarettes, particularly those containing nicotine, can cause health complications and addiction, which may result in a subsequent initiation of psychoactive substance use. This systematic review and meta-analysis evaluated the prospective association between e-cigarette use and subsequent use of psychoactive substances in young people aged 10-24 years. Pooling of data from the identified longitudinal studies showed that ever e-cigarette users had a higher risk for subsequent cannabis, alcohol, and unprescribed Ritalin/Adderall use compared to never e-cigarette users. The findings indicate a need for interventions to reduce e-cigarette use in adolescents and young adults.
How facial reactions to others’ expressions are influenced by perceived social traits
Authors: Berger Michael , Freiwald Winrich A.
Published: January 2023

Humans spontaneously mimic facial expressions. Facial mimicry is not a mere motor copy but reflects social context in service of social goals like facilitating affiliation. The study of social context has focused on face-external settings like interpersonal relations. The impact of face-internal social context on facial mimicry has, surprisingly, not been investigated yet. Here, we test if social information carried by facial shape, specifically trustworthiness and dominance, influences facial mimicry. We used virtual avatar faces from an established database known to be perceived as strongly (non-)dominant or (non-)trustworthy and added smiling, frowning, and neutral expressions. We video-recorded facial reactions and asked participants to self-report on arousal, valence, and dominance they experienced. In a second task, the same participants were asked to deliberately imitate facial expressions. We show that self-reported feelings differ in arousal, valence, and dominance by expression, and that valence is affected by dominance and trustworthiness traits. Both social traits also affect the deliberate imitation of the expression, in particular movements around the eyes. However, we did not find any significant impact of any facial social trait on spontaneous facial expressions. Thus, our results show that, despite the spatial overlap of facial social traits and expression signals, facial mimicry circuits may be immune to the face-internal social context in the absence of an external social context.
The Impacts of Anxiety and Motivation on Spatial Performance: Implications for Gender Differences in Mental Rotation and Navigation
Authors: Lourenco Stella F. , Liu Yaxin
Published: January 2023

Despite extensive research on gender differences in spatial cognition, the potential roles of affective and situational factors in accounting for these differences remain relatively understudied. Here we discuss the impacts of spatial anxiety and motivation in mental rotation and navigation tasks, particularly their roles in explaining the gender performance gaps. We highlight the distinction between approach and avoidance motivation, as well as interactions between anxiety and motivation. Attention, working memory, and response strategy are discussed as mechanisms by which anxiety and motivation may affect performance on spatial tasks. Implications for a broader approach that also considers other psychological variables, such as confidence, are discussed.