bluuebunny/crossref_metadata_2025 huggingface dataset:
THE RELATIONSHIP BETWEEN INTELLECTUAL CAPITAL AND INTELLECTUAL ASSETS IN THE DEVELOPMENT OF SOCIO-ECONOMIC SYSTEMS
Authors: KARPENKO A. , KARPENKO N. , PUSTOVIT Y.
Published: May 2024

Abstract. The aim of the research is to analyze the relationship between intellectual capital and intellectual assets, which are crucial for competitive development and creating a favorable environment for innovation, creativity, increased competitiveness, and attracting investments. Identifying the main conditions and factors of intellectual capital development is an important task as it determines the economic strength, prosperity, and quality of life at the organizational, regional, and national economy levels. Methodology. In the process of completing the tasks in the study, the following methods and approaches were used: the abstract-logical method was employed for clear goal and task definition; the analytical-monographic approach was applied in the analysis of literary sources, legislative acts related to the relationship between intellectual capital and intellectual assets; the method of causal analysis was used to determine cause-and-effect relationships influencing the development of intellectual capital, human capital, and intellectual assets and their interrelationships. Results. The article analyzes the results of scientific research by scholars, formed theoretical and methodological aspects regarding the relationship between intellectual capital, intellectual assets, human capital, and their impacts on the development of socio-economic systems, determining the stages of managing intellectual assets in the stages of manifestation. The scientific novelty lies in determining and substantiating the places, characteristics, and relationship between intellectual capital and intellectual assets in the development of economic systems. Practical significance. The recommendations provided in the article can be applied in developing specific elements of Ukraine's strategy in the context of intellectual and human capital development.
Дискусійні аспекти проблематики правового міфу
Authors:   Харківський національний економічний університет імені Семена Кузнеця, Рогова Олена
Published: May 2024

The axiological aspects of legal myth and mythological perception of reality were analyzed and it was found that several interrelated properties of the studied myth can be identified, which allow to assert the thesis about its own and instrumental value. In particular, the intrinsic (ontological) value of legal myth is manifested in the formation of a certain sign system, which is a reflection of legal reality in the minds of man (or society). Mythological perception of reality, in our opinion, is authorial, selective, to some extent biased. Instead, the instrumental value of legal myth is observed in the processes of human cognition of the world and legal reality, in the process of identification and self-identification of man. In particular, the legal myth is not just a means of knowing and identifying the phenomena of legal reality, but serves as a reliable apologist for the value and moral choice of man and his behavior, such a sign system that has a certain „indulgence” for any human action (inaction). The instrumental value of the legal myth is not limited to the framework of the epistemological process, the tasks of observation and cognition, but has a powerful potential for influence and transformation of legal reality. Awareness of this potential of the legal myth opens a wide space for its application in order to root in the legal consciousness of man and, ultimately, society as a whole, the relevant legal (or anti-legal) values. The principles of interaction of the legal myth and the modern state are determined. Any legal myth seeks to spread, social support, wider recognition, in the most ambitious end – official recognition and legitimacy, which is impossible without a strong state function. The legitimation of the legal myth occurs through its spread in society, receiving social support and rooting first in the legal consciousness of individuals, and gradually – in the public legal consciousness. It can be argued that legal myths permeate all levels of legal reality of the modern state, from legal consciousness (man and society), and ending with the processes of lawmaking, law enforcement, interpretation.
NRP1 COMO POTENCIAL ALVO MOLECULAR PARA MEDULOBLASTOMA
Authors: Araujo Moisés Augusto de , Nassif Paulo Afonso Nunes , Fratini Livia , Roesler Rafael , Rabello Samuel , Carmo Alexsandro Batista da Costa , Isolan Gustavo Rassier
Published: May 2024

Introdução : Meduloblastoma é um tumor maligno, altamente agressivo e de rápido crescimento que surge no cerebelo ou no assoalho do quarto ventrículo e tronco cerebral, especialmente em crianças. Mesmo com os avanços na terapia, a morbimortalidade permanece um grande desafio. Por isso, novos tratamentos são necessários para reduzir esses estágios.
Objetivo : Revisar a relação NRP1 (neuropilina 1) e meduloblastoma como potencial alvo terapêutico e, também, com sobrevida global.
Método : Trata-se de revisão narrativa realizada nas bases de dados PubMed e Scielo. A busca utilizou as seguintes palavras-chave: “ neuropilinas, meduloblastoma, tumores malignos, pediatria ”. Os critérios de inclusão foram artigos de revisão, estudos experimentais, pesquisas pré-clínicas e clínicas, em inglês e português, e disponíveis em texto completo. Os artigos selecionados foram analisados ​​com base nas tecnologias abordadas, perspectivas futuras e desafios conceituais, doenças referidas e ideia central do artigo.
Resultado : Foram incluídos 30 artigos
Conclusão : Os meduloblastomas possuem altos níveis transcricionais de neuropilina (NRP1) e seus baixos níveis relacionados com a menor sobrevida global, especialmente nos SHH. Nesse sentido, o NRP1 e seu complexo sistema de atuação aparecem como alvo potencial de terapias oncológicas para tumores específicos.
Agricultural performance of biomaterials mulch based on nitrosamine-free natural rubber
Authors: Suchat Sunisa , Praksong Kanokwan , Muangprathub Jirapond , Srisawat Theera , Abdullah Nor Hakimin , Boonrasri Siwarote
Published: May 2024

Natural rubber mulching material is generally more environmentally friendly than conventional mulch. Artificial straw and mulch derived from natural rubber latex (NRL) with no nitrosamines present were used as sustainable alternatives to substitute for conventional materials such as rice straw and polyethylene plastic. A real-time recorded field study employed the Internet of things with tracking devices and sensors to monitor the growth and quality of cucumber plants (Cucumis sativus L.) over a 50-day period. The results of the study highlight the superior efficiency of artificial straw, showcasing enhanced growth and quality. The NRL mulch contained a nanocellulose (CNC) filler and was vulcanized at room temperature. The addition of 3 parts CNC per hundred rubber significantly enhanced the mechanical properties of the NRL formulation, particularly its tensile (22.13 ± 2.26 MPa) and tear strengths (39.13 ± 4.58 N/mm). The NRL mulch was demonstrated to promote plant growth and increase yield. It was developed to ensure the safety of agricultural products and to support environmental conservation.
Objetivos de desarrollo sostenible
Authors:   Universidad Cooperativa de Colombia, Monsalve Prada Mónica Janeth , Martínez Ospina Rosa Amalia
Published: May 2024

Desde hace algunas décadas, los Gobiernos han manifestado interés en el desarrollo sostenible de sus Estados, sin embargo, en sus inicios, no fueron presentadas ningunas propuestas de trabajo o planteamiento de acciones específicas. En el 2000, se desarrolló la reunión denominada Cumbre del Milenio, organizada por las Naciones Unidas. En esta Cumbre, llegaron a acuerdos relacionados con metas y objetivos que pudieran ser alcanzables a nivel mundial y se establecieron plazo para el logro de estas metas. A esto le llamaron “objetivos de desarrollo del milenio”. En septiembre del 2015, la Asamblea General de la ONU adoptó una nueva agenda, denominada la Agenda 2030 para el Desarrollo Sostenible. Esta organización reconoció que es una agenda ambiciosa en su alcance y su amplitud, pues los nuevos objetivos planteados se abordan de manera integrada desde todas las dimensiones sociales, económicas y ambientales del desarrollo sostenible. En esta oportunidad, fueron planteados 17 Objetivos de Desarrollo Sostenible (ODS). Esta Agenda también lleva adelante las cuestiones inconclusas de los Objetivos del Milenio (ODM). Los objetivos de desarrollo sostenibles no son considerados una forma de justificar el trabajo de los Estados, sino un marco y una herramienta para el futuro y es una obligación de todos.
İç Turizmdeki Pandemi Etkisinin Kümelenme Analizi Kullanılarak İncelenmesi: Türkiye Örneği
Authors: Zaman Serhat , Erdoğan Hatice , Eşim İbrahim
Published: May 2024

Bu çalışmada, belediye ve bakanlık belgeli tesislere gelen yerli turistlere ilişkin istatistikler, mekânsal istatistik yöntemlerine göre incelenmiştir. 2018, 2020 ve 2022 yılları esas alınarak pandemi sürecinin iç turizmdeki etkisi ortaya konulmuştur. Verilerin mekânsal dağılımını belirleyebilmek için küresel ve yerel olarak Moran’s I yöntemleri kullanılarak mekânsal otokorelasyon analizi yapılmıştır. İlçe ölçeğinde gerçekleştirilen analiz sonucunda, pandeminin tercih edilen turizm mekânlarında, yerli turistler özelinde belirgin bir değişime sebep olmadığı ortaya konulmuştur. Salgın dönemi ve salgın sonrasındaki dönemde sıklıkla ifade edilen radikal değişiklik söylemleri en azından bu süreler içerisinde istatistiksel olarak gerçekleşmemiştir. Ancak değişim uzun bir zaman dilimine ihtiyaç duymaktadır. Yaşanan krizler sektörü etkilediği gibi turistlerin tercihlerini de etkilemektedir. Risk ve krizleri azaltmak, planlamaların yapılması, sürdürülebilir turizm gelişiminin sağlanması, ekonomik, sosyal ve çevresel sonuçları izlemek için turist tutum ve davranışlarını takip etmek önem arz etmektedir. Bundan dolayı çalışmada coğrafi kümelenme eğilimi değerlendirilmiştir. Sonuçlar, Türkiye’de iç turizmin giderek daha fazla fark edilir hale gelen coğrafi kümelenme eğiliminde olduğunu ortaya koymaktadır.
Tribbles pseudokinase 3 promoted renal fibrosis by regulating the expression of DNA damage-inducible transcript 3 in diabetic nephropathy
Authors: Kong Lulu , Kong Liusha , Li Peipei , Gao Li , Ma Hongqin , Shi Bimin
Published: May 2024

Diabetic nephropathy (DN) is a severe complication of prolonged diabetes, impacting millions worldwide with an increasing incidence. This study investigates the role of tribbles pseudokinase 3 (TRIB3), a protein implicated in the progression of DN, focusing on its mechanisms underlying glomerular damage. Through analysis of the Gene Expression Omnibus (GEO) database, we identified TRIB, among differentially expressed genes (DEGs) in streptozotocin (STZ)-treated C57BL/6J mice. Both in vitro and in vivo experiments were conducted to examine the effects of TRIB3 inhibition on high glucose (HG)-induced damage in podocytes and DN mouse models. The results demonstrated that TRIB3 inhibition reduced inflammatory responses and extracellular matrix (ECM) production inMPC5 cells, mediated by the downregulation of DNA damage-inducible transcript 3 (DDIT3) - a critical regulator of proinflammatory cytokine secretion and ECM synthesis. Inhibiting TRIB3 decreased inflammatory factors and ECM deposition in diabetic mice in vivo, confirming its pivotal role in DN pathogenesis. These findings indicate that TRIB3 and its interaction with DDIT3 contribute significantly to DN by promoting inflammatory cascades and ECM accumulation, presenting potential therapeutic targets for managing the disease.
Evaluation of water use impacts caused by real estate development with gentrification traits in the metropolitan area of San Luis Potosí
Authors: Abraham Cárdenas-Tristán , Sergio Alfredo Galvan-Medina , Hao Wu , Oscar Reyes-Cardenas , Rodolfo Cisneros-Almazán
Published: May 2024

Water resource management is a technical, social, and political issue worldwide. Water, being a public good, is characterized as follows: “Unlike private goods, public goods are indivisible and cannot be satisfactorily met by the market or other private initiatives. The provision of public goods requires cooperation or coercion, either through collective action or effective government.” In this sense, water is a human right, as stated by the UN in its sixth sustainable development goal, which aims to “ensure availability and sustainable management of water and sanitation for all.” Gradually, housing in the city of San Luis Potosí has shifted from being affordable for the entire population to becoming increasingly unattainable. Due to the growing demand for housing driven by common population growth and urban development, in recent years, vertical construction-both residential and commercial-has been implemented as a potential solution to this phenomenon, now accounting for 10% of constructions in this area in the capital city, according to the Registro Único de la Vivienda as of 2023. However, such constructions have brought new challenges to urbanization in San Luis Potosí city. As noted by Lozano Niño Y., areas, where high-socioeconomic-status apartment buildings with gentrification features proliferate, were not planned to support high population densities. Eventually, one of the possible consequences of high densification in these areas will be the inadequacy of basic services such as water. While vertical housing offers an alternative to maximize land use within the urban sprawl and could address housing demands, there is also a need to improve public services and urban infrastructure in the surrounding areas where these constructions are planned to prevent social inequality in terms of public service distribution. This study aims to analyze the relationship between case studies—buildings with gentrification features-and their impact on the use and distribution of potable water among the inhabitants of the urban sprawl of San Luis Potosí, by using geospatial methods and technologies.
Recent advancements in fluoroquinolones removal techniques from wastewater
Authors: Husain Saqer
Published: May 2024

Fluoroquinolones (FQs) are widely used antibiotics for therapeutic purposes, yet their extensive usage and unwise disposal led to antibiotic resistance as well as their widespread across the environment and becoming a major contaminates in water bodies as the wastewater treatment plants are not capable removing of FQs completely. Knowing the latter, the researchers endeavored to find techniques for the detection and removal of such contaminates from the disposed water from different facilities. This review highlights some of the recently and currently developed techniques for detection and removal. It discusses also different adsorbents used to remove FQs from wastewater. All in all, the removal of such leading contaminates from water would inhibit their spread across different environmental spheres thus promoting better environmental health.
Slide Preparation and Transect Counting of Paleoecological Microfossils - SPaTCoPM v1
Authors: C. O'Toole Megan , Patel Richa , Niccolo Cerasoni Jacopo
Published: May 2024

Paleoecology attempts to reconstruct history through geochemical isotopic studies, trace fossil analyses, examination of microbe communities, and the presence or lack of microfossils. Ancient lakes are useful for reconstructing paleoecology because they accumulate sediment through time. Paleobotanical microfossils, including diatoms and phytoliths, allow inference of vegetation, pH, salinity, water chemistry, and environmental temperature, among others. Here, we propose a protocol split into two sections to prepare slides and count diatoms and phytoliths along transects. Researchers can develop an ecological history by analyzing microfossils from different locations and times. As an example, we apply this method to study the palaeobotanical microfossils of an 820 cm deep stratigraphy, composed of 10.3my Miocene diatomite, from a high-elevation desert paleolake in Northern Nevada (Fernley District). The preliminary results hint at a complex climatic and environmental variance. Another application of this method includes the development of environmental interpretations and hypotheses regarding the future of modern vegetation.
dSTORM of actin in fixed HeLa cells v1
Authors: Bruggeman Ezra , peters ruby
Published: May 2024

This is a protocol for the preparation of a HeLa DTS cells for dSTORM imaging of the actin network. This protocol was used to generate the data shown in Figure 4 of the following publication: Bruggeman et al., POLCAM: Instant molecular orientation microscopy for the life sciences. bioRxiv 2023.02.07.527479 (Feb 2023), doi: https://doi.org/10.1101/2023.02.07.527479
Untargeted lipidomics of Tagless Lyso-IP v1
Authors: Dong Wentao
Published: May 2024

Lysosomal biology is increasingly implicated in neurodegenerative diseases and health. It has traditionally been difficult to profile the metabolomic homeostasis of the lysosome in disease states. To overcome this challenge we have developed the Tagless Lyso-IP method to rapidly prepare lysosome enriched samples from human peripheral blood. This protocol details the processing and untargeted analysis of nonpolar metabolites derived using the Tagless Lyso-IP method.
The importance of social support for elderly people
Authors: Mahmutović Jasmina , Duhović Dalila , Salihović Amela , Branković Suada , Jaganjac Amila , Bojičić Samir
Published: May 2024

Introduction: Social support is not a one-way relationship but is based on the connections people have with other people, groups, and the wider community. This study aimed to assess the perception of social support by people in the third age and to investigate the correlation of social support with the sociodemographic characteristics of the respondents.
Methods: A quantitative cross-sectional study was conducted with 147 elderly people who actively use the services of the Center for Health Promotion and Improvement “Generacija” in Sarajevo. The Multidimensional Scale of Perceived Social Support (MSPSS) was used to assess social perceptions.
Results: The results show a weak negative relationship between age and the total scale (r = −0.199, p = 0.05), with older people having lower scores on the total scale. A significant relationship was found between the subscale other factors and age (r = −0.202, p = 0.05). The evaluation of the performance of daily activities correlates weakly with the evaluation of the friend’s subscale (r = 0.186, p = 0.05). The friend’s subscale correlates significantly with the quality of social life (r = 0.227, p = 0.05). The subjective assessment of the quality of social life after arriving at the center showed a correlation with the overall scale score (r = 0.182, p = 0.05) and especially with the friend subscale (r = 0.219, p = 0.05), with the increase in social life and the subscales examined in both cases.
Conclusion: Users of the “Generacija” center rate social support on the MSPSS with high scores, with users receiving the most support from family. The sociodemographic characteristics of the respondents have an impact on the perception of social support by the users of the Center for Health Promotion and Improvement “Generacija,” more specifically; they were statistically significantly influenced by age, the way of performing daily activities, the quality of social life and the quality of social life after arrival at the Center.
Características clínicas y epidemiológicas de población pediátrica con urolitiasis en tres instituciones del Eje Cafetero desde 2016 hasta 2019
Authors:   Universidad Tecnológica de Pereira, López-Velásquez Angela Patricia , Zapata-Chica Carlos Andrés ,   Universidad Tecnológica de Pereira, Martínez José William ,   Universidad Tecnológica de Pereira
Published: May 2024

Introducción: la incidencia de urolitiasis en niños sigue aumentando y la mayoría tiene factores predisponentes metabólicos, infecciosos o anatómicos, sin embargo, en nuestro medio desconocemos su comportamiento clínico. Objetivos: identificar las características clínicas y epidemiológicas de niños con urolitiasis. Metodología: estudio transversal multicéntrico realizado de 2016-2019 en pacientes entre 0-18 años de tres instituciones del Eje Cafetero (Colombia) con diagnóstico imagenológico o recuperación de cálculos en la orina. La información se obtuvo a partir de historias clínicas electrónicas. Resultados: se incluyeron 64 pacientes y la mediana de edad fue 12 años con una relación mujer hombre 1:1,13. El 27% tuvo sobrepeso y obesidad y el 33% contó con historia familiar. Los signos clínicos más comunes fueron dolor abdominal (58%), infección urinaria y hematuria. El 59% presentó alguna alteración metabólica: la hipercalciuria fue la más frecuente (34%) seguida de hipocitraturia (17%). La composición principal fue oxalato y carbonato de calcio (36%). En un paciente se confirmó cistinuria. La ecografía fue la imagen más empleada. Se hizo tratamiento conservador en 46 niños (72%). La litotripsia extracorpórea fue la intervención quirúrgica más común. El 34% de los pacientes recurrió y hubo complicaciones en 51%. La principal, obstrucción del tracto urinario (37%), con mayor riesgo a menor edad y peso. Conclusiones: la urolitiasis fue más común en adolescentes, el principal síntoma fue el dolor abdominal y la ecografía fue la imagen de elección. La mayoría de los niños recibieron manejo conservador y el alto porcentaje de desórdenes metabólicos refuerza la importancia del tamizaje.
Infección grave por SARS-CoV-2 en gestantes del Hospital Universitario de Neiva en el sur colombiano: reporte de casos
Authors:   Hospital Universitario de Neiva, Panqueba-Salgado Juanita , Guzmán-Losada Célico ,   Hospital Universitario de Neiva, Ospina-Marin Henry Alexander ,   Hospital Universitario de Neiva, Javela-Rugeles Carlos Eduardo ,   Universidad Surcolombiana, Antonio Rodríguez Jairo ,   Hospital Universitario de Neiva
Published: May 2024

Entre septiembre y noviembre de 2020, 4 gestantes menores de 35 años tuvieron diagnóstico de neumonía y preeclampsia grave. Las pacientes requirieron ingreso a unidad de cuidados intensivos (UCI), ventilación mecánica y oxigenación por membrana extracorpórea. En los exámenes paraclínicos se registró aumento de la proteína C reactiva y de lactato deshidrogenasa, linfopenia y reducción de la proporción neutrófilo/linfocito. Un neonato fue positivo para SARS-CoV-2. Tres madres y un neonato fallecieron. La preeclampsia se ha relacionado con COVID-19 en gestantes. Llama la atención la alta mortalidad encontrada y la transmisión vertical en uno de los casos. En conclusión, el desarrollo de preeclampsia grave en todos los casos pudo ser un factor más que contribuyo con el desenlace fatal en 3 de ellos. Se sugiere que la linfopenia y la reducción de la proporción neutrófilo/linfocito pueden ser útiles como factor pronóstico. Futuros estudios permitirán dilucidar las consecuencias del COVID-19 en la gestación.
Orchestration of Markets and Bureaucratic Knowledge Production in the Moscow Transportation Reform
Authors: Muleev Egor
Published: May 2024

This article examines the role of bureaucracy in the process of reforming Moscow’s transportation system. With reliance on the intellectual history of neoliberalism, the concept of “orchestration,” an institutionalist economics, and an empirical case study, I argue that a market embodies itself in the form of bureaucracy. The agency in the provision of norms and regulations, calculations and forecasts, orders of economic exchange, and knowledge production concentrates in the hands of bureaucrats regardless of their formal attachment to state or private entities. Bureaucrats define fundamental issues of how markets should function; they design and control the system of money redistribution. The case of dismantling Moscow’s trolleybus system provides fruitful data on the agency of bureaucracy in transportation reform under the label of implementing “best practice” scenarios favourable to a neoliberal toolkit.
UKRAINIAN CAROLS OF THE INTERNET SEGMENT 2022-2023: TRANSMISSION OF THE MEANINGS
Authors:   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, Zakalska Yaryna , Ivanovska Olena ,   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine
Published: May 2024

Background. Investigated here are the carols that appear in the Internet segment in December 2022 – January 2023 during the full-scale russian-Ukrainian war as a reaction to massive russian missile attacks on the territory of Ukraine. It is noted that the appearance of such texts at the same time caused a discussion among users of social networks, about whether these carols have something in common with "traditional" carols, which were the focus of attention of Ukrainian scientists, in particular: P. Chubynskyi, V. Hnatiuk, I. Franko, F. Kolessa, M. Drahomanov and others. By the way, the problem of belonging of texts that are distributed in social networks to folklore is discussive among the professional community. The issue of fixing such texts is also very actual. The authors agree with the opinion of V. Hnatiuk, expressed in the article "War and Folk Poetry", about the necessity to pay close attention to the folk creativity caused by the war, and to record the texts that appeared during the war. Accordingly, the aim of the article is to analyze the texts of Christmas carols distributed in social networks in the winter of 2022–2023, to reveal the degree of their folklore character, to compare them with the texts of calendar-ritual texts recorded by Ya. Holovatskyi, V. Hnatiuk, I. Franko, P. Chubynskyi, Olena Pchilka or taken from the Digital Archive of Folklore of Slobozhanshchyna and Poltavashchyna (https://www.folklore.kh.ua/), and to observe their common and distinctive features. The object of this article are the texts recorded by the authors in social networks "Facebook", "Telegram", "Twitter", "Instagram" during December 2022 – January 2023. The subject of the research is the genre, thematic and functional features of the analyzed texts. Меthods. In preparing this publication, general scientific and specifically folkloristic research methods were used, in particular, the method of systematic analysis, comparative, historical-genetic, and historical-chronological. Results. Therefore, two groups of studied carols are distinguished: parody carols (on the popular motif "Good evening to you, Mr. Master") and so-called children's carols, which in wartime conditions arise in an adult environment taking into account extratextual reality. Conclusions. It is shown that the researched carols are based on ancient texts, at the same time they retain their formula, but they are supplemented with new folklore meanings. It is emphasized that such texts perform various functions, the most important of which are informative, creative-expressive, ethno-unifying, the function of documenting events and, above all, psychotherapeutic. Attention is also drawn to two types of transmission: vertical and indirect.
THE POETIC SPACE OF THE WORK OF DIOGENES LAERTIUS "LIVES AND THOUGHTS OF EMINENT PHILOSOPHERS"
Authors:   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, Zvonska Lesia
Published: May 2024

The article examines the poetic component in the discourse of the work of Diogenes Laertius "Life and Thoughts of Famous Philosophers" in the aspect of ancient biography and doxography and in correlation with the cultural and historical realities of ancient Greek panegyrics and invective. The stylistic features of epigrammatic poetry about philosophers are characterized: apotheosis, heroization and glorification or, on the contrary, satire, invective and parody. Panegyristics is embodied in the form of deification, ascension to heaven to the Olympians, invective - in ridiculing human flaws and the shortcomings of philosophers and discrediting their teachings. In the studied epigrams, philosophers, along with prominent historical figures and winners of all-Greek competitions, became objects of public worship for the first time. The poetic works of the philosophers themselves (Solon, Xenophanes, Parmenides, Empedocles, Epicharmus, Plato, Arkesilaus, Cratetus, Bion) are also analyzed. , quotations by various philosophers of ancient Greek poetry, their paraphrases and parodies of famous poets. The poetic discourse is described, presented both in the diachrony of the authors involved by Diogenes, starting from Homer and ending with late Hellenistic epigrammatists (more than 250 poems by 32 well-known and little-known authors), and in their genre diversity (epic, lyric, elegy, tragedy, comedy, canticles, oracles , epigram, epitaph, dialogue-diatribe). The metric schemes of poetic works, both quoted by Diogenes and the author's original poetry (dactylic hexameter, pentameter, logaeds, in particular, Archebulian measure, meliamb, prokeleusmatic, holiamb) are indicated; the source base of poetic works used by Diogenes is indicated, from ancient and Byzantine collections (Palatine Anthology, Planudеa Anthology) to scholarly editions of ancient Greek poetry. The rhetorical devices of the panegyric and much more often mocking epigrams of Diogenes himself, of which there are 52 works, are considered.
DEVELOPMENT TRENDS OF THE MINING INDUSTRY OF UKRAINE IN THE GLOBAL CONTEXT
Authors:   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, MYKHAILOV Volodymyr
Published: May 2024

he main global trends in the development of the mining industry in recent years are considered; a constant increase in the intensity of development of the earth's subsoil and extraction of mineral products in recent decades is shown; the world's largest mining countries are highlighted. It was established that China (23 % of world production), the USA (12 %), Russia (9 %), and Australia (7 %) are the leading countries in terms of production volume. China, the USA, Russia, Saudi Arabia and Australia are the leaders in terms of the value of mined products. It has been established that in recent years (2015–2021) the growth of mining of lithium, rare earths, niobium, titanium, bauxite, nickel, fluorite, graphite, etc. was especially rapid, while the mining of tin, mercury, antimony, uranium, tantalum, technical diamonds, etc. decreased. It was established that at the end of the 20s, the development of the mining industry was negatively affected by the consequences of the pandemic, but already at the end of 2020, the state of the mining industry began to improve. The role and place of Ukraine in the global mining industry is shown, which ranks 24th in the world in terms of volume of production, and 36th in terms of the value of mined products; and takes leading positions in the production of iron, manganese, titanium, etc. In recent years (2015–2021), the production of iron, manganese, titanium, feldspar, graphite, sulfur, and coking coal has increased significantly in Ukraine, but the production of gallium, bentonite, salt, zircon, coal, and uranium has decreased.
STRATEGIC IMPORTANCE OF RARE EARTH ELEMENTS FOR MODERN TECHNOLOGIES AND PROSPECTS OF DOMESTIC DEPOSITS
Authors:   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, KURYLO Mariia , КОSHАRNА Sofiia ,   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine
Published: May 2024

In the context of sustainable development, the reorientation of a wide range of technological industries is an inevitable phenomenon that predetermines the perturbations of the established list of raw materials of strategic importance. Changes in priorities are primarily derived from the transition need to innovative approaches in order to solve old problems and ensure all the needs of modern society. So far, integrating into numerous global economic chains, rare earth elements open up a whole range of new opportunities. Within the study information on the main areas of REE use, its market conditions, existing and projected price dynamics were analyzed and summarized; a systematization of stimulating and restraining factors of REE mineral resource base development according to economic, ecological, geological, resource and technological indicators was also made; the connection of the modern "Green Energy Transition" global strategy with the work intensification rate at potential REE mining objects is traced, arguments regarding the primary need to concentrate efforts on replenishing the market for elements of the cerium group, which includes neodymium and praseodymium are given as well. Based on the results of the study, a conclusion regarding the main factors in the development of the REE market was made, and the most promising areas for geological prospecting and mining implementation on the territory of Ukraine were identified.
STRESS FIELDS AND GEOLOGICAL STRUCTURE OF WESTERN CLOSURE OF HORLIVKA ANTICLINE OF DONBAS PART 2. STRESS AND STRAIN FIELDS
Authors:   Taras Shevchenko National University of Kyiv, Kyiv, Ukraine, NIKITENKO Oleksandr
Published: May 2024

Background. In tectonophysical studies, particular importance is placed on the mechanism of formation of large complex deformation structural elements, and the Horlivka anticline of the Donets Basin serves as such an example. Its importance lies not only in its complex structural composition and development mechanism but also in its potential impact on safe and efficient coal mining. This study aims to analyse the geological structure, stress and strain fields of the western closure of the Horlivka anticline that could be useful in forecasting geological factors for coal mining operations. Methods. The paleostress analysis was performed on the collected fault orientation and kinematic data using Gushchenko's kinematic method based on the analysis of tectonic displacement vectors along slickensides. Mesoregional stress field characteristics were reconstructed by statistical processing of local stereographic solutions. The relative age chronology and staging of tectonic stresses were studied using the stress monitoring method. The characteristics of the principal axes of the total strain field were processed using the GEOS software. Results. Mesoregional stress field is characterised by a subhorizontal NW–SE-oriented maximum principal stress axis and a subhorizontal NE–SW-oriented minimum principal stress axis. This stress regime is classified as a strike-slip regime and is the youngest one (Alpine orogeny) for the Donets Basin. The evolution of tectonic loading conditions of the studied structure is characterised by a deformation series of six stress regimes from the oldest (normal) to the youngest (strike-slip). Stretching axis of the strain ellipsoid is oriented NW and N–S, and shortening axis is oriented NE, nearly orthogonal to the anticline axis. Strike- and oblique-slip faulting regimes of the total strain field were determined for most of the study area, and the deformation has occurred under shear conditions, as indicated by the Lode–Nadai coefficient. Conclusions. A structural pattern of deformation elements, including a conjugate strike-slip fault system of the shear zone, a dome-shaped fold, and longitudinal thrusts in its limbs, may be interpreted as a single pattern of structural paragenesis developed by right-lateral displacements along the longitudinal strike-slip fault system within the Horlivka anticline paraxial part. Fragments of mutual symmetry between the stress and strain fields can be taken as evidence of their genetic relationship.
A Multidisciplinary Approach to the Diagnosis, Treatment and Prevention of Developmental Disorders of Children in the First Years of Life
Authors: Trushkina S.V.
Published: May 2024

Objectives. The early detection of deviations in the child development is an important task — both in medical and psychological and pedagogical practice. As a result of the variety of specialized approaches to the development of children in the first years of life, a general idea of the health and development of a young child is often obscured by numerous private assessments. The task of developing a unified synthetic approach towards understanding and as- sessing development by specialists of different profiles seems very difficult.

Methods. A brief comparative-historical analysis was performed of trends in the change of modern approaches to- wards the diagnosis, therapy, and prevention of developmental disorders in children in the first years of life.

Results. Arguments are made for the predominant influence of multidisciplinarity in theoretical thinking and clinical practice. At the same time, there has been a tendency towards increased demand on the part of specialists for interdisciplinarity when constructing an overall picture of development, the state of mental health and diseases in a child. The shift in priorities when assessing the development of children by modern researchers is shown — from the levels of formation of cognitive, motor, speech or everyday skills towards the emotional and social levels. There has been a growing understanding among specialists of various profiles of the fundamental importance of relationships with close adults for the development and mental health of an infant and young child. A brief review of the articles included in the thematic issue is made, convincingly illustrating interdisciplinarity and multidisciplinarity in modern diagnosis, therapy, correction and the prevention of childhood developmental disorders.

Conclusions. The situation of the insufficient provision of Russian specialists working with children in the first years of life with psychodiagnostic tools and scientifically grounded correctional practices remains, the attention of science organizers in the field of medicine, psychology and pedagogy to this has been drawn.
The Mental State of Parents in Diseases of Young Children
Authors: Solondaev V.K. , Pisareva M.V.
Published: May 2024

Objectives. Children’s illnesses negatively affect their mental and physical development, causing anxiety and psychological discomfort to parents, since increased demands are placed on parental care. In turn, the discomfort of the parents increases the risk for the normal development of the child. In the Yaroslavl region, about 7% of all younger aged children are hospitalized annually. Of these, 97% are initial, 8% are in serious condition. Researchers describe relatively stable psychological characteristics of parents of sick children. In order to psychologically optimize the treatment process, the previously undescribed psychological state of mothers of infants hospitalized with their children in the Yaroslavl Oblast Children’s Clinical Hospital health care institution was investigated.

Methods. The sample consisted of 34 women hospitalized with their children under 3 years of age. Using the “Layout of the mental state” method by A.O. Prokhorov, three mental states were assessed: the actual state at the time of the research, the habitual state and the state at the onset of the child’s disease. The state of health of the child was also assessed by the respondents on a scale from 0 to 10. The data covering the period of 2019—2023 hospitalizations of the children of early age were used.

Results. The actual mental states reported by respondents were significantly worse than their habitual ones, according to descriptor groups Psychic Processes and Feeling. The actual mental states were better than the ones at the onset of disease, according to descriptor groups Psychic Processes, Physiological Reactions, Feeling and Behavior. The evaluation of a child’s health is associated only with a change in the state of the group of Mental processes descriptors (Kendall’s Tau 0.30; z = 2.4; p-value = 0.02).

Conclusions. Two opposite changes in the mental state of mothers during hospitalization of children were revealed: the worsening compared with the usual state, improvement in the mental state compared to the onset of the child’s disease. Changes in mental state in seven of the eight groups of descriptors are independent of the parents’ assessment of the child’s health at the time of the examination. A small sample implies a special assessment of the sustainability of the results.
Exploring the Impact of an Instructional Video on Educators' Views of Teaching Disability and Accessibility Awareness
Authors:   , Friedman Elizabeth , Vorndran Christina M.
Published: May 2024

This convergent parallel mixed methods study explored barriers to teaching disability and accessibility awareness in the early elementary classroom and assessed the impact of an instructional video on educators' current perceptions and future teaching practices. Through one-on-one, semi-structured interviews on Zoom and a pretest, intervention, posttest on Qualtrics, the researcher answered the following research questions. 1. How frequently do participants currently teach disability and accessibility awareness topics in their classrooms? 2. What do participants view as the current barriers to teaching these topics in their classrooms? a. What is an effective means to reduce or remove the barriers? 3. Does viewing The Playground Project instructional video significantly impact participants' willingness, confidence, and views of difficulty regarding integrating disability and accessibility awareness into their teaching? In the study, the researcher utilized both the constructivist paradigm and the transformative framework, which dovetail to support problem-solving through close attention to participant voice (Creswell, 2013). The transformative framework furthers the notion that research can support marginalized groups (Creswell, 2013). In the study, Critical Disability Theory, or CDT, was entwined with the transformative framework, as CDT challenges "the social norms that define particular attributes as impairments, as well as the social conditions that concentrate stigmatized attributes in particular populations" (Minich, 2016, as cited in Schalk, 2017, p. 1).
How Far Are We From Achieving Delabeling of False Penicillin/ß-Lactam Allergy Alerts? A Population Problem
Authors: Tejedor-Alonso MA , Perez-Encinas M , Sanz Márquez S , Martinez Simon JJ , Moreno-Nuñez L , Gonzalez-Moreno A , Macias-Iglesias J , Rosado-Ingelmo A
Published: May 2024

Interest in finding efficient ways to remove penicillin allergy alerts has grown as a result of awareness of the considerable excess of falsenegative diagnoses in patients with penicillin allergy labels (90%-95%), the poorer course with non–ß-lactam antibiotics, the increase in bacterial resistance, and the fact that these problems can affect up to 20% of the population in some countries. The strategies proposed have generated many publications in countries where the number of allergists to conduct such studies is low.
In many cases where delabeling is performed, the risk of ß-lactam allergy is low, and a single penicillin challenge is sufficient to delabel the alert. However, other less “ultrarapid” strategies can be used to administer a ß-lactam during an admission for infection and thus postpone delabeling until traditional drug allergy consultations.
However, the definitive withdrawal of ß-lactam alerts is threatened by nonremoval of alerts in electronic health records and by the reactivation or nonsynchronization of alerts between electronic systems at different levels of care.
Allergy departments need to reflect on how to implement practices that enable rapid and efficient delabeling of drug allergy alerts, especially in patients with major comorbidities.
Evaluation of the time, labor, and money required for manual and automated nucleic acid (RNA) isolation for the detection of SARS-COV-2 by QRT-PCR using the qiamp viral RNA mini kit and kingfisher flex
Authors: Roat Chetana , Dave Nilay Harshadkumar
Published: May 2024

We undertook this cross-sectional investigation to assess the time, manpower, and average run cost per sample using manual Qiamp Viral RNA micro kit (Qiagen) and automated kingfisher flex instrument extraction methods for SARS-Cov-2 identification.

The study used 120 Viral Transport Media-collected nasopharyngeal/ oropharyngeal swabs.

Magnetic bead-based RNA extraction was performed using the Thermo Fisher Scientific kingfisher flex instrument and manual Extraction was Silica membrane-based Qiagen spin column kits. The TaqPath™ COVID-19 Combo Kit from Thermo Fisher Scientific was used for detecting SARS-CoV-2 target genes.

Human technique took 40 minutes longer than automation. It cost more to automate than to manually labor. These disparities in time, effort, and cost affect laboratory operations, offering pros and cons for each method. This suggests that positive or negative was consistent regardless of viral load or RNA concentration.

The study found that automated RNA extraction yielded better results compared to manual extraction. The automated sample processing system saved time, people, and money. In resource-limited or low-throughput labs, manual extraction may be preferable. Manual methods are laborious, require more hands-on time, and risk cross-contamination and technical blunders.
A Duty to Rescue and Its Costs
Authors: Wójtowicz Stanisław , Dominiak Łukasz , Wysocki Igor
Published: May 2024

The purpose of the present paper is to analyse the problem of cost generated by
the performance of a duty to rescue. The authors consider three distinct views of this
problem by confronting a scenario in which one party decides to rescue another,
where providing such assistance seems to involve an infringement upon the property
rights of the third party. For example, A rescues drowning B but in the process of doing
so A apparently trespasses upon C’s land. The question that the authors pose is:
Assuming that there is a duty to rescue, who should be charged with the cost of what
seems to be an infringement upon the third party’s property rights? The paper analyses
the following possibilities: the cost should be borne by (a) the victim of the emer-
gency, (b) the rescuer, (c) the third party whose rights seem to have been encroached
upon. Even though the authors begin with a pronouncedly libertarian assumption
about the third party’s absolute property rights, in the course of the discussion they
come to the conclusion that it is exactly this assumption that should be further probed
and ultimately relaxed in order to reach the most plausible solution to the present
dilemma.
The child tax credit as an example of the state’s family policy
Authors: Mańczyk Paweł , Wróblewska Dominika
Published: May 2024

Ulga na dzieci jest ulgą podatkową w podatku dochodowym od osób fizycznych. Celem artykułu było przybliżenie tej preferencji podatkowej. Autorzy, dokonując szczegółowej analizy odnośnych przepisów prawnych oraz przeglądu orzecznictwa sądowego, podjęli próbę oceny, czy ulga na dzieci realizuje założenia, jakie przyświecały ustawodawcy przy jej wprowadzeniu. W podsumowaniu wskazano cztery mankamenty ulgi na dzieci:
1. Ulga dostępna jest jedynie dla podatników rozliczających podatek dochodowy od osób fizycznych na zasadach ogólnych.
2. Prawo do ulgi przy wychowywaniu jednego dziecka uzależnione jest od kryterium dochodowego, które od 2013 roku nie było waloryzowane.
3. Wartość ulgi na dzieci jest znikoma, a jej wysokość nie zmieniła się od 2015 roku.
4. Prawa do ulgi nie mają osoby sprawujące faktyczną opiekę nad niespokrewnionymi, pełnoletnimi osobami wymagającymi takiej opieki z uwagi na wąskie rozumienie obowiązku alimentacyjnego.
Autorzy sformułowali propozycje rozwiązania ww. mankamentów.
W opracowaniu jako podstawową metodę badawczą zastosowano metodę dogmatyczno-prawną obejmującą analizę aktów prawnych, literatury przedmiotu oraz orzecznictwa sądów