bluuebunny/crossref_metadata_2025 huggingface dataset:
Surface orange patinas on the limestone of the Batalha Monastery (Portugal): characterization and decay patterns
Authors: Ding Yufan , Redol Pedro , Angelini Emma , Mirão José , Schiavon Nick
Published: July 2021

Samples of orange patinas found on a limestone window tracery and an ornament of the Batalha Monastery have been investigated by X-ray micro-diffractometry (μ-XRD) and low-vacuum scanning electron microscopy coupled with energy dispersive spectrometry (LV-SEM + EDS). The aim of the study was to determine the composition of the layered patinas, assess whether they have been intentionally applied or naturally formed, and study their degradation patterns. Preliminary results revealed that the orange patinas on the window tracery and the ornament showed different compositions and appearance, suggesting distinct formation pathways. Orange patinas on the ornament, which are now showing decay and delamination patterns, mainly consisted of gypsum with hematite as a minor component, implying the possibility of an intentional application of a mixture of ochre and lime as tint plaster. Orange patinas on the window tracery show, instead, the presence of Ca-oxalates, abundant weddellite, and minor whewellite, with minor hematite suggesting the yellowish/orange color as being due to Ca-oxalate patinas imbedding soil dust airborne particles. Such patina was possibly formed naturally either by the chemical attack due to atmospheric air pollutants from traffic exhausts emissions or by bacterial activity. No delamination was observed on the window tracery sample with granular decohesion as the major decay phenomenon. A comparison was made between this patina and the so-called scialbatura, a surface yellowish coating often found by conservators on limestone and marble in ancient monuments in the Mediterranean region.
Deepening our understanding of which policy advice to expect from prioritizing SDG targets: introducing the Analytic Network Process in a multi-method setting
Authors: Toth Werner , Vacik Harald , Pülzl Helga , Carlsen Henrik
Published: July 2021

The indivisibility principle of the 2030 Agenda is considered key for the implementation of policies in pursuit of the Sustainable Development Goals (SDGs). Therefore, science is not only asked to develop new methods for assessing SDG target interactions but also to translate findings of methodological insights into policy advice for easy take-up by policymakers. The present paper demonstrates how to adopt the multi-criteria analysis technique Analytic Network Process (ANP) for prioritizing SDG targets in considering all positive and possible indirect SDG target interactions at once. The application of the ANP is linked to a multi-method setting embracing positive scores derived from the analytical methods Nilsson-scale, a cross-impact matrix, and network analysis techniques. This supports the prioritization of SDG targets when considering n-order neighbours in a network with respect to their synergies. The ANP allows evaluating the synergistic potential and progress controllability of SDG target rankings calculated by CI-matrix metrics and thus provides conclusions on the importance of n-order interactions of SDG targets in a network for the final ranking. We showed that the application of a combination of different analytical methods improves the overall quality of the formulated policy advice regarding its scope and methodological profoundness. In this context, we compared the analytical methods involved with respect to their ability to formulate policy advice and finally presented a framing how to translate methodological results into concrete and applicable policy advice.
Predictive maintenance integrated production scheduling by applying deep generative prognostics models: approach, formulation and solution
Authors: Zhai Simon , Kandemir Meltem Göksu , Reinhart Gunther
Published: July 2021

To harness the full potential of predictive maintenance (PdM), PdM information has to be used to optimally plan production and maintenance actions. Hence, operation-specific modelling of degradation, i.e. predictions of the health condition under time-varying operational conditions, has to be realized. By utilizing operation-specific degradation information, maintenance and production can be planned with regard to each other and thus, predictive maintenance integrated production scheduling (PdM-IPS) is enabled. This publication proposes a novel PdM-IPS approach consisting of two interacting modules: an operation-specific Prognostics and Health Management (PHM) module and an integrated production scheduling and maintenance planning (IPSMP) module. Specifically, the mathematical problem of the IPSMP module based on an extended version of the maintenance integrated flexible job shop problem is formulated. A two-stage genetic algorithm to efficiently solve this problem is designed and subsequently applied to simulated condition monitoring, as well as real industrial data. Results indicate that the approach is able to find feasible high quality PdM integrated production schedules.
The role of grit and resilience in children with reading disorder: a longitudinal cohort study
Authors: Hossain Bushra , Chen Yingtong , Bent Stephen , Parenteau China , Widjaja Felicia , Haft Stephanie L. , Hoeft Fumiko , Hendren Robert L.
Published: July 2021

Prior studies have suggested that grit and resilience predict both academic and career success. However, these qualities have not been examined in children with reading disorder (RD). We therefore investigated whether grit and resilience were associated with anxiety, depression, academic performance, and quality of life (QOL) in these students. This 3-year longitudinal cohort study included 163 participants with RD from 3 schools. Evaluations were completed by parents and/or teachers every 3 months. The Grit and Resilience Scale was adapted from the 10-item Connor-Davidson Resilience Scale and the 12-item Grit Scale. Outcome measures included anxiety (School Anxiety Scale – Teacher Report and the 8-item Spence Children’s Anxiety Scale), depression (Short Mood and Feelings Questionnaire), academic performance, and QOL (Pediatric QOL Inventory 4.0). Multivariate linear regression models (adjusting for age and sex) assessed the associations at baseline. Repeated measures analysis using mixed-effects models assessed the relationship longitudinally. There were statistically significant associations between grit and resilience and all outcomes at baseline and over time. After adjusting for age and sex, improved grit and resilience was associated with decreased anxiety (β =  − 0.4, p < 0.001) and improved academic performance (β = 0.5, p < 0.001) when grit and resilience was measured by teachers, as well as decreased depression (β =  − 0.3, p < 0.001) and improved QOL (β = 0.6, p < 0.001) when grit and resilience was measured by parents. Grit and resilience are significantly related to mental health, academic performance, and QOL in children with RD. This suggests that interventions to improve grit and resilience may lead to positive benefits.
Chronic angiotensin receptor activation promotes hepatic triacylglycerol accumulation during an acute glucose challenge in obese-insulin-resistant OLETF rats
Authors: Godoy-Lugo Jose A. , Thorwald Max A. , Hui David Y. , Nishiyama Akira , Nakano Daisuke , Soñanez-Organis Jose G. , Ortiz Rudy M.
Published: July 2021

Purpose

Angiotensin receptor blockers (ARBs) can ameliorate metabolic syndrome (MetS)-associated dyslipidemia, hepatic steatosis, and glucose intolerance, suggesting that angiotensin receptor (AT1) over-activation contributes to impaired lipid and glucose metabolism, which is characteristic of MetS. The aim of this study was to evaluate changes in the lipid profile and proteins of fatty acid uptake, triacylglycerol (TAG) synthesis, and β-oxidation to better understand the links between AT1 overactivation and non-alcoholic fatty liver disease (NAFLD) during MetS.

Methods

Four groups of 25-week-old-rats were used: (1) untreated LETO, (2) untreated OLETF, (3) OLETF + angiotensin receptor blocker (ARB; 10 mg olmesartan/kg/d × 8 weeks) and (4) OLETF ± ARB (MINUS; 10 mg olmesartan/kg/d × 4 weeks, then removed until dissection). To investigate the dynamic shifts in metabolism, animals were dissected after an oral glucose challenge (fasting, 3 and 6 h post-glucose).

Results

Compared to OLETF, plasma total cholesterol and TAG remained unchanged in ARB. However, liver TAG was 55% lesser in ARB than OLETF, and remained lower throughout the challenge. Basal CD36 and ApoB were 28% and 29% lesser, respectively, in ARB than OLETF. PRDX6 abundance in ARB was 45% lesser than OLETF, and it negatively correlated with liver TAG in ARB.

Conclusions

Chronic blockade of AT1 protects the liver from TAG accumulation during glucose overload. This may be achieved by modulating NEFA uptake and increasing TAG export via ApoB. Our study highlights the contributions of AT1 signaling to impaired hepatic substrate metabolism and the detriments of a high-glucose load and its potential contribution to steatosis during MetS.
Growth, coalescence, and etching of two-dimensional overlayers on metals modulated by near-surface Ar nanobubbles
Authors: Wei Wei , Pan Jiaqi , Lin Haiping , Euaruksakul Chanan , Li Zhiyun , Huang Rong , Wang Li , Wang Zhujun , Fu Qiang , Cui Yi
Published: July 2021

The synthesis of high-quality ultrathin overlayers is critically dependent on the surface structure of substrates, especially involving the overlayer-substrate interaction. By using in situ surface measurements, we demonstrate that the overlayer-substrate interaction can be tuned by doping near-surface Ar nanobubbles. The interfacial coupling strength significantly decreases with near-surface Ar nanobubbles, accompanying by an “anisotropic to isotropic” growth transformation. On the substrate containing near-surface Ar, the growth front crosses entire surface atomic steps in both uphill and downhill directions with no difference, and thus, the morphology of the two-dimensional (2D) overlayer exhibits a round-shape. Especially, the round-shaped 2D overlayers coalesce seamlessly with a growth acceleration in the approaching direction, which is barely observed in the synthesis of 2D materials. This can be attributed to the immigration lifetime and diffusion rate of growth species, which depends on the overlayer-substrate interaction and the surface catalysis. Furthermore, the “round to hexagon” morphological transition is achieved by etching-regrowth, revealing the inherent growth kinetics under quasi-freestanding conditions. These findings provide a novel promising way to modulate the growth, coalescence, and etching dynamics of 2D materials on solid surfaces by adjusting the strength of overlayer-substrate interaction, which contributes to optimization of large-scale production of 2D material crystals.
Debris-carrying behaviour of bark lice immatures preserved in 100 million years old amber
Authors: Kiesmüller Christine , Haug Joachim T. , Müller Patrick , Hörnig Marie K.
Published: July 2021

Camouflage strategies, including several types of concealments, are known for several insect groups today, such as immatures of some species within reduviid bugs (Hemiptera), lace wings (Neuroptera), caddisflies (Trichoptera) and bark lice (Psocodea). However, camouflage has only rarely been reported in the fossil record. Here we report findings of four bark lice preserved in 100 Million year old amber from Myanmar, which represent the first fossil evidence for masking behaviour in Cretaceous representatives of Psocodea. All four of these, probably not conspecific, and immature bark lice carry sand granules and organic material atop their back, which probably resulted in camouflaging them against the background (e.g. bark) to avoid detection by predators. We briefly summarise concepts of camouflage and examples of decoration behaviour within insects, as well as possible “receiver” (i.e. predators) of the camouflage of the herein described bark lice. The exact phylogenetic position of the specimens remains unclear, due to the scarce fossil record of Cretaceous immatures of Psocodea, as well as extant immatures. This demonstrates the importance of findings as reported here, as a wide knowledge of morphology and development of a certain group is crucial to get an insight into their evolution and reconstructing environments in deep time.
Lactobacillus plantarum PS128 Promotes Intestinal Motility, Mucin Production, and Serotonin Signaling in Mice
Authors: Chen Chih-Ming , Wu Chien-Chen , Huang Chin-Lin , Chang Min-Yu , Cheng Shih-Hsuan , Lin Ching-Ting , Tsai Ying-Chieh
Published: July 2021

Lactobacillus plantarum PS128 has been reported as a psychobiotic to improve mental health through the gut–brain axis in experimental animal models. To explore its mechanism of action in the gut, this study aimed to analyze the effects of L. plantarum PS128 ingestion on naïve and loperamide (Lop)-induced constipation mice. We found that, in the two mouse models, the weight, number, and water content of feces in the L. plantarum PS128 group were higher than those in the vehicle control group. Histological observation revealed that L. plantarum PS128 increased the level of colonic mucins including the major mucin MUC2. In addition, the charcoal meal test showed that L. plantarum PS128 significantly increased the small intestine transit in naïve mice, but not in the Lop-treated mice. Since intestinal serotonin has been found to modulate motility, we further analyzed the expression of genes related to serotonin signal transduction in the small intestine of naïve mice. The results showed that L. plantarum PS128 significantly altered the expression levels of Tph1, Chga, Slc6a4, and Htr4, but did not affect the expression levels of Tph2, Htr3a, and Maoa. Furthermore, immunohistochemistry revealed that L. plantarum PS128 significantly increased the number of serotonin-containing intestinal cells in mice. Taken together, our results suggest that L. plantarum PS128 could promote intestinal motility, mucin production, and serotonin signal transduction, leading to a laxative effect in mice.
Sexuality Education in the Digital Age: Modelling the Predictors of Acceptance and Behavioural Intention to Access and Interact with Sexuality Information on Social Media
Authors: Olamijuwon Emmanuel , Odimegwu Clifford
Published: July 2021

Introduction

Diverse literature on sexual health promotion using social media suggests that increasing information reach and interaction are crucial. This study integrated the unified theory of acceptance and use of technology (UTAUT) to model the predictors of young adults’ behavioural intention to use and interact with sexuality education on social media.

Methods

A total of 936 young adults in Kenya, Nigeria, and South Africa who had access to the internet and Facebook were recruited via Facebook’s advertising platform from 22 May 2020 to 8 June 2020. A structural equation model was fitted on the sample to identify the individual attributes associated with the intention to use and interact with sexuality information on social media.

Results

About 84% of the young adults in the sample consider social media an appropriate medium for sexual health communication, with Facebook being the most preferred (40%) digital platform for sexual health promotion. Results from the structural equation model showed that performance expectancy (β = 0.18, P < 0.001), social influence (β = 0.09, P = 0.047), effort expectancy (β = 0.25, P < 0.001), facilitating condition (β = 0.33, P < 0.001), and attitude (β = 0.10, P = 0.039) were significantly associated with the intention to access sexuality education on social media. These factors (except attitude) were also significantly associated with the intention to interact with sexual health information on social media.

Conclusions

Young people with internet access are amenable to receiving and interacting with sexuality information on social media. The use of social media for sexuality education is associated with whether such use is free of effort, endorsed by society, align with their engagements with other messages, and helps them achieve improvement in their sexual and reproductive health.

Policy Implications

Strategies to increase access and interaction with sexuality information on social media help young people make an informed decision about their sexuality. Such use should also be free of effort, align with the way they interact with other information on social media, and supported by the society.
Smooth determinantal varieties and critical loci in multiview geometry
Authors: Bertolini Marina , Notari Roberto , Turrini Cristina
Published: July 2021

Linear projections from$$\mathbb {P}^k$$Pkto$$\mathbb {P}^h$$Phappear in computer vision as models of images of dynamic or segmented scenes. Given multiple projections of the same scene, the identification of sufficiently many correspondences between the images allows, in principle, to reconstruct the position of the projected objects. A critical locus for the reconstruction problem is a variety in$$\mathbb {P}^k$$Pkcontaining the set of points for which the reconstruction fails. Critical loci turn out to be determinantal varieties. In this paper we determine and classify all the smooth critical loci, showing that they are classical projective varieties.
Biological control of soil-borne phytopathogenic fungi through onion waste composting: implications for circular economy perspective
Authors: Chorolque A. , Pellejero G. , Sosa M. C. , Palacios J. , Aschkar G. , García-Delgado C. , Jiménez-Ballesta R.
Published: July 2021

The production of onion waste derived mainly from bulbs affected by fungal diseases, during onion classification and storage presents an important agro-environmental issue in onion production regions. Composting is an environmentally friendly strategy to recycle agricultural waste and produce organic fertilizers. Modifications of the microbial community in soil can affect the ability of pathogen propagules to survive, germinate and infect plant roots. Hence, the main objective of this work was to exploring the mechanisms involved on the presence of three soil-borne phytopathogenic fungi during the composting process of onion waste under the hypothesis if that the resulting compost effectively prevents or minimizes the dispersion of phytopathogenic fungi. To this end, three composting piles of 60 tonnes each were built by layering onion waste affected by phytopathogenic fungi and cow dung at 1:1 ratio. Temperature, moisture, pH, electrical conductivity (EC) and Aspergillus niger, Penicillium sp. and Fusarium sp. growth were monitored for 100 days. During the first 28 days of composting, the presence of phytopathogenic fungi increased significantly showing thereafter a downward trend. Final estimations of fungal populations densities indicated a predominance of A. niger and an effective reduction in the abundance of Fusarium sp. This pilot-scale work demonstrates the feasibility of composting onion waste contaminated with phytopathogenic fungi and highlights the positive environmental impact associated with this practice. Therefore, the composting of onion waste and cow dung is a feasible and sustainable procedure to recycle onion waste and to promote circular economy in onion production regions.
Regenerative Engineering Animal Models for Knee Osteoarthritis
Authors: Esdaille Caldon Jayson , Ude Chinedu Cletus , Laurencin Cato T.
Published: July 2021

Osteoarthritis (OA) of the knee is the most common synovial joint disorder worldwide, with a growing incidence due to increasing rates of obesity and an aging population. A significant amount of research is currently being conducted to further our understanding of the pathophysiology of knee osteoarthritis to design less invasive and more effective treatment options once conservative management has failed. Regenerative engineering techniques have shown promising preclinical results in treating OA due to their innovative approaches and have emerged as a popular area of study. To investigate these therapeutics, animal models of OA have been used in preclinical trials. There are various mechanisms by which OA can be induced in the knee/stifle of animals that are classified by the etiology of the OA that they are designed to recapitulate. Thus, it is essential to utilize the correct animal model in studies that are investigating regenerative engineering techniques for proper translation of efficacy into clinical trials. This review discusses the various animal models of OA that may be used in preclinical regenerative engineering trials and the corresponding classification system.

Lay Summary

Osteoarthritis (OA) of the knee is the most common synovial joint disease worldwide, with high rates of occurrence due to an increase in obesity and an aging population. A great deal of research is currently underway to further our understanding of the causes of osteoarthritis, to design more effective treatments. The emergence of regenerative engineering has provided physicians and investigators with unique opportunities to join ideas in tackling human diseases such as OA. Once the concept is proven to work, the initial procedure for the evaluation of a treatment solution begins with an animal model. Thus, it is essential to utilize a suitable animal model that reflects the particular ailment in regenerative engineering studies for proper translation to human patients as each model has associated advantages and disadvantages. There are various ways by which OA can occur in the knee joint, which are classified according to the particular cause of the OA. This review discusses the various animal models of OA that may be used in preclinical regenerative engineering investigations and the corresponding classification system.
Flow field designs developed by comprehensive CFD model decrease system costs of vanadium redox-flow batteries
Authors: Prumbohm E. , Becker M. , Flaischlen S. , Wehinger G. D. , Turek T.
Published: July 2021

Different flow field designs are known for vanadium redox-flow batteries (VFB). The best possible design to fulfil a variety of target parameters depends on the boundary conditions. Starting from an exemplary interdigitated flow field design, its channel and land dimensions are varied to investigate the impact on pressure drop, channel volume, flow uniformity and limiting current density. To find a desirable compromise between these several partly contrary requirements, the total costs of the VFB system are evaluated in dependence of the flow field’s dimensions. The total costs are composed of the electrolyte, production and component costs. For those, the production technique (injection moulding or milling), the pump and nominal power density as well as depth of discharge are determined. Finally, flow field designs are achieved, which lead to significantly reduced costs. The presented method is applicable for the design process of other flow fields and types of flow batteries.

Graphical abstract
The Political Economy of Public Pensions
Authors: Norcross Eileen , Smith Daniel J.
Published: July 2021

Public pensions in the United States face an impending funding crisis in the wake of the financial crisis and the COVID-19 recession. Many cities and states will struggle to meet these growing obligations without major cuts in government services, reneging on pension promises, or raising taxes. This Element examines the development of the pension crisis through the lens of political economy. We analyze the knowledge and incentive problems inherent in the institutional structure, governance, and accounting of public pensions. We conclude by offering several institutional, governance, and reporting reforms to address the pension funding crisis.
Law and Ethics for Australian Teachers
Authors: Butlin Mark , McNamara Noeleen , Anglin Kerrie
Published: July 2021

Getting to grips with law and policy can be daunting for beginning and established teachers alike. Law and Ethics for Australian Teachers provides an overview of the professional, legal and ethical issues teachers may encounter in the classroom and the broader school environment. This book breaks down the relevant case law, as well as state and territory legislation and policy, in an accessible way to help readers navigate these complex issues. It covers topics including duty of care and mandatory reporting, work health and safety issues, family court orders and parenting plans, suspensions and exclusions, and criminal law issues. Each chapter features case studies, definitions of key terms, detailed scenarios and end-of-chapter questions to help readers understand a wide range of professional issues. Written by a team of authors with both teaching and legal expertise, Law and Ethics for Australian Teachers is an essential resource for pre- and in-service teachers.
Learning and Teaching in Early Childhood
Authors: Boyd Wendy , Green Nicole , Jovanovic Jessie
Published: July 2021

Learning and Teaching in Early Childhood: Pedagogies of Inquiry and Relationships is an introduction for early childhood educators beginning their studies. Reflecting the fact that there is no single correct approach to the challenges of teaching, this book explores teaching through two lenses: teaching as inquiry and teaching as relating. The first part of the book focuses on inquiry, covering early childhood learning environments, learning theories, play pedagogies, approaches to teaching and learning, documentation and assessment, and the policy, curriculum and regulatory requirements in Australia. The second part explores relationships in early childhood contexts and covers topics such as fostering meaningful and respectful relationships with children, and working with families, staff and the wider community. Written by well-respected academics in the field, Learning and Teaching in Early Childhood is a vital resource for those entering the early childhood education and care profession.
Brain Toxoplasmosis Comorbid with Autoimmune Disease: Complicated Immune Response And Case Demonstration
Authors: Graham Alice , Fong Crystal , Naqvi Asghar , Lu Jian-Qiang
Published: July 2021

Toxoplasmosis is an opportunistic infection caused by Toxoplasma gondii (TG), commonly involving the brain. Symptomatic clinical disease of TG infection is much more commonly associated with immunodeficiency; clinicopathological manifestations of brain toxoplasmosis are linked to individual immune responses including brain infiltration of T-cells that are thought to fight against toxoplasmosis. In patients with autoimmune diseases, immune status is typically characterized by T-cell infiltration and complicated mainly by immunosuppressant and/or immunomodulatory treatment. In this study, we demonstrate clinical and radiological features correlated with pathological features of brain toxoplasmosis at different disease stages in a patient with coexisting autoimmune diseases, including systemic lupus erythematosus and autoimmune hepatitis. The infiltration of CD8+ T-cells in toxoplasma immunostaining-positive acute lesions was greater than that in toxoplasma immunostaining-negative chronic lesions. We also review previously reported cases of brain toxoplasmosis with comorbid autoimmune diseases. Our present case and literature review suggest that brain toxoplasmosis in patients with autoimmune diseases may be asymptomatic unless disease complications occur; it may present as an incidental finding at postmortem examination of rapidly developed lesions. T-cell infiltration in patients with autoimmune diseases and coexisting toxoplasmosis may be at least partially reduced; ultimately, the roles of T-cell infiltration in brain toxoplasmosis deserve further investigation.

Learning Objectives

Discuss complicated immune response to toxoplasmosis in patients with autoimmune diseases.

Describe clinical, radiological, and pathological features of brain toxoplasmosis in patients with autoimmune diseases.
3D-Printed Endoport vs. Open Surgery for Evacuation of Deep Intracerebral Hemorrhage
Authors: Garcia-Estrada Everardo , Morales-Gómez Jesús Alberto , Garza-Báez Azalea , Sotomayor-González Arturo , Palacios-Ortiz Isaac Jair , Mercado-Flores Mariana , Martínez-Ponce de León Angel Raymundo
Published: July 2021

Background:

Large-sized clinical trials have failed to show an overall benefit of surgery over medical treatment in managing spontaneous intracerebral hemorrhages (ICH); less invasive techniques have shown to decrease brain injury caused by surgical manipulation in the standard open approach improving the clinical outcomes of patients. Thereby, we propose a low-cost 3D-printed endoport for a less invasive ICH evacuation. In this study, the authors compare the clinical outcomes of early surgical evacuation using a 3D-printed endoport vs. a standard open surgery (OS).

Methods:

A retrospective analysis was conducted comparing patients who underwent early evacuation of a deep hypertensive ICH through an endoport vs. OS at a single center from August 2017 to March 2019. Demographic, clinical, and radiologic data were reviewed. The primary outcomes were the 90-day post-stroke functional outcome and mortality.

Results:

A total of 36 patients were included. The two cohorts (18 endoport; 18 OS) showed no statistically significant differences in demographic, clinical, and radiologic characteristics, including median admission hemorrhage volume, Glasgow Coma Scale, and ICH scores. At 90-day post-stroke, 44% of patients in the endoport group and 17% in the OS group had a favorable functional outcome (mRS 0–3) (p = 0.039); moreover, the endoport group showed lower mortality (33% vs. 72%, p = 0.019).

Conclusions:

This study suggests that an endoport-assisted ICH evacuation may have better functional outcomes and lower mortality than OS. The proposed device could provide a safe, low-cost alternative for ICH’s surgical treatment. More rigorous research is hence needed to assess the potential benefits of this technique.
Patent Law and the Materiality of Inventions in the California Oil Industry: The Story of Halliburton v. Walker, 1935–1946
Authors: Con Díaz Gerardo
Published: July 2021

This article examines a patenting conflict between the Halliburton Oil Well and Cementing Company and an independent inventor named Cranford Walker. It argues that Halliburton’s effort to lower the barriers to entry into the oil well depth measurement industry facilitated the re-emergence of materiality as a pre-condition for the patent eligibility of inventive processes. In 1941, Walker sued Halliburton for infringement of three of his patents, and Halliburton responded with an aggressive defense aimed at invalidating them. Over the next five years, the courts handling this conflict adopted very narrow legal theories developed during the Second Industrial Revolution to assess the patent eligibility of inventions that involved mental steps—processes such as mathematical computations, which people can perform in their minds. The resulting legal precedent cleared the path for Halliburton’s short-term industrial goals and continued to shape patent law for the rest of the century.
STABILITY AND CHANGES IN PARTY IDENTIFICATION IN TAIWAN: AN EXAMINATION OF LIFE CYCLE, COHORT, AND PERIOD EFFECTS
Authors: Chen Rou-lan
Published: July 2021

This article builds on the theoretical debate over age, period, and cohort effects (APC) and explores how these factors might affect Taiwan's partisan stability. We conducted a two-level multinomial logit random effects model using survey data from 1991 to 2020 to disentangle the APC effects. Our findings challenge Converse's core assumption that partisanship strengthens with age. As a new democracy, Taiwan's party affiliations remain fluid, and we do find evidence of period effects, particularly associated with cross-Strait crises that favor the DPP. However, generational replacement is the most significant factor driving party identity changes in Taiwan. With generational replacement, the Kuomintang is burdened by the image of a century-old party. The Democratic Progressive Party (DPP) had previously fared better among young cohorts but has recently lost its support from millennials. The youngest generation increasingly refuses to associate with the traditional political parties. It seems reasonable to expect that the new generational forces will restructure the Blue–Green cleavage and expand the ideological diversity of Taiwan's party system.
The Life and Death of a Child: Mortuary and Bodily Manifestations of Coast–Interior Interactions during the Late Formative Period (AD 100–400), Northern Chile
Authors: Torres-Rouff Christina , Pimentel Gonzalo , Pestle William J. , Ugarte Mariana , Knudson Kelly J.
Published: July 2021

Camelid pastoralism, agriculture, sedentism, surplus production, increasing cultural complexity, and interregional interaction during northern Chile's Late Formative period (AD 100–400) are seen in the flow of goods and people over expanses of desert. Consolidating evidence of material culture from these interactions with a bioarchaeological dimension allows us to provide details about individual lives and patterns in the Late Formative more generally. Here, we integrate a variety of skeletal, chemical, and archaeological data to explore the life and death of a small child (Calate-3N.7). By taking a multiscalar approach, we present a narrative that considers not only the varied materiality that accompanies this child but also what the child's life experience was and how this reflects and shapes our understanding of the Late Formative period in northern Chile. This evidence hints at the profound mobility of their youth. The complex mortuary context reflects numerous interactions and long-distance relationships. Ultimately, the evidence speaks to deep social relations between two coastal groups, the Atacameños and Tarapaqueños. Considering this suite of data, we can see a child whose life was spent moving through desert routes and perhaps also glimpse the construction of intercultural identity in the Formative period.
Glacial kettles as archives of early human settlement along the Northern Rocky Mountain Front
Authors: Lanoë François B. , Zedeño M. Nieves , Jansson Anna M. , Holliday Vance T. , Reuther Joshua D.
Published: July 2021

The Northern Rocky Mountain Front (hereafter Northern Front) is a prominent geographic feature in archaeological models of human dispersal in the terminal Pleistocene and Early Holocene of North America. Testing those models has been arduous because of local geomorphological factors that tend to obliterate or otherwise limit access to archaeological finds of relevant age. In this paper, we present well-stratified archaeological and environmental records dating back to 14,000–13,000 cal yr BP from the site of Billy Big Spring (Blackfeet Indian Reservation, Montana), located on a glacial kettle, a type of landform that has been largely ignored by regional archaeological research to date. Findings from Billy Big Spring show the continuous use of the Northern Front foothills throughout the major climatic and environmental disturbances of the Early Holocene, and possibly the terminal Pleistocene as well. As such, Billy Big Spring contributes to refining several archaeological models of early settlement of the Northern Front, particularly those that posit differential use of foothills versus plains settings during the midst of the Holocene Thermal Maximum. The record at Billy Big Spring also suggests that kettles, regardless of physiographic setting, provide a yet unsuspected and unsampled potential for preserving high-quality and easily accessible early archaeological and paleoenvironmental records.
Timescales of magmatism and metamorphism in the Connemara Caledonides: insights from the thermal aureole of the Dawros–Currywongaun–Doughruagh Complex, western Ireland
Authors: O’Driscoll Brian , Chew David M.
Published: July 2021

Zircon separates from the contact aureole of the syn-tectonic Dawros–Currywongaun–Doughruagh Complex, western Ireland, are studied to constrain the nature and timing of magmatism associated with the early stages of the Grampian Orogeny. The samples analysed come from the uppermost part of the Dalradian Supergroup in northern Connemara (the Ben Levy Grit Formation), where a laterally extensive (>10 km) package of metamorphosed siliciclastic sedimentary rocks containing heavy mineral seams crops out. The seams mainly comprise magnetite, but zircon is also present in greater than accessory quantities. The seams have been locally reworked at granulite-facies metamorphic conditions during intrusion of the Dawros–Currywongaun–Doughruagh Complex magmas. Here we combine in situ mineral chemical and U–Pb geochronological analyses of zircons from samples of these heavy mineral seams collected at different locations in the Dawros–Currywongaun–Doughruagh Complex thermal aureole. An important finding is that the zircons studied have magmatic trace-element compositions, interpreted here as a function of their growth during contact metamorphic-induced partial melting. The zircons yield a range of U–Pb spot ages whose uncertainties suggest a maximum duration of zircon growth of ˜11 Ma, between 477.1 and 466.1 Ma, though it is likely that zircon growth occurred much more quickly than this. The age constraints revealed here match well with the range of 475 to 463 Ma previously proposed for the Grampian Orogeny overall in Connemara and lend useful support to models that argue for high-intensity, relatively short-lived Grampian orogenesis in the Connemara Caledonides.
Evaluation of alfalfa cultivars under rainfed Mediterranean conditions
Authors: Baxevanos D. , Loka D. , Tsialtas I. T.
Published: July 2021

Twenty alfalfa cultivars were tested, under rainfed conditions in central Greece, for forage yield, agronomic and nutritive value in order to identify adaptive responses contributing to high resilience and productivity. From 2014 to 2017, five harvests (H1 to H5) per season were conducted. Two cultivars were also grown as irrigated checks. Annual and total dry matter (DMA and DMT) and harvest ratios (RH) were estimated. DMT was reduced by 42.9–48.1% under ambient rainfall compared to irrigated checks, which received 50.2% more water. The seasonal yield distribution demonstrated two contrasting strategies, however, equally effective for high resilience under rainfed conditions. The winter-active imported cultivars were the most resilient in the driest year, potentially due to their ability to exploit autumn rains, whereas the locally adapted genotypes were more productive in summer. The spring harvest ratio (RH1) was more indicative (r = 0.94, P < 0.01) of cultivar productivity, compared to plant survival (r = 0.65, P < 0.01), whereas the autumn harvest ratio (RH5) was representative of productivity under extreme drought (r = 0.53, P < 0.05). RH1 and RH5 were increased by 11.8 and 12.3%, respectively, whereas the summer ratios (RH3, RH4) were reduced by 47.3%, under rainfed v. irrigated conditions. Two Australian cultivars (‘Blue Ace’, ‘Icon’) achieved the highest RH5 suggesting an adaptive response by being more productive in autumn. However, the development of specifically adapted cultivars in terms of higher summer yield and plant survival may be necessary to cope with future climatic changes in the Mediterranean region.
Social networks and their impact on access to health care: insights from older widows living alone in Kottayam, South India
Authors: George Mathew Sunil , Gaitonde Rakhal , Davey Rachel , Sukumaran Vyas , Mohanty Itismita , Upton Penney
Published: July 2021

The feminisation of ageing observed across the world is a significant challenge in many societies. Women's greater longevity is associated with the increased likelihood of age-related disability and morbidity. Furthermore, gendered disadvantage and poverty can make access to health care increasingly problematic in later years. Among the Indian states, Kerala has the highest number of residents above the age of 60 and many are older widows. Given this context, this paper explores what promotes access to health care for older widows living alone in the south Indian state of Kerala. Thirty-two in-depth interviews, eight focus group discussions and eight units of participant observation were carried out among widows, health-care providers and key informants. Applying a reflexive inductive approach to our analysis, the main barriers to access that emerged were altered family structures and loneliness, whilst enablers included good social networks and access to neighbourhood clinics. Our participants’ social networks were drawn from three levels: family, neighbourhood and the wider community. The ability to form a personal community from their social networks and the quality of relationships within this community strongly predicted the capacity to access health care. Efforts to improve access to health care for older widows requires a response that is rooted in the socio-cultural context of the community. Comprehensive social protection policies that promote initiatives to engender social capital among the older population, decentralised primary health-care services, and the training and sensitisation of health service staff would be key to promote equitable access for older widows.
Testing whether implicit emotion regulation mediates the association between discrimination and symptoms of psychopathology in late childhood: An RDoC perspective
Authors: Vargas T.G. , Mittal V.A.
Published: July 2021

Discrimination has been associated with adverse mental health outcomes, though it is unclear how early in life this association becomes apparent. Implicit emotion regulation, developing during childhood, is a foundational skill tied to a range of outcomes. Implicit emotion regulation has yet to be tested as an associated process for mental illness symptoms that can often emerge during this sensitive developmental period. Youth aged 9–11 were recruited for the Adolescent Brain Cognitive Development (ABCD) study. Associations between psychotic-like experiences, depressive symptoms, and total discrimination (due to race, ethnicity, nationality, weight, or sexual minority status) were tested, as well as associations with implicit emotion regulation measures (emotional updating working memory and inhibitory control). Analyses examined whether associations with symptoms were mediated by implicit emotion regulation. Discrimination related to decreased implicit emotion regulation performance, and increased endorsement of depressive symptoms and psychotic-like experiences. Emotional updating working memory performance partially mediated the association between discrimination and psychotic-like experiences, while emotional inhibitory control did not. Discrimination and implicit emotion regulation could serve as putative transdiagnostic markers of vulnerability. Results support the utility of using multiple units of analysis to improve understanding of complex emerging neurocognitive functions and developmentally sensitive periods.
Transcatheter closure of Abernethy malformation associated with interrupted inferior caval vein and other systemic venous anomalies
Authors: Shakya Samir , Saxena Anita , Ramakrishnan Sivasubramanian
Published: July 2021

Abernethy malformation is a rare entity. We report a 5-year-old boy presenting with severe pulmonary hypertension in whom Abernethy malformation and inferior caval vein interruption were diagnosed by CT angiography. In addition, the iliac veins were thrombosed with multiple venous collateral drainage. This abnormal venous anatomy caused difficulty in device closure of the Abernethy malformation, which was successfully closed using a vascular plug.
Single pulmonary valve cusp agenesis first detected by computed tomography reconstruction
Authors: Chiariello Giovanni A. , Vahdat Olivier , Bruguiere Eric , Abouliatim Issam
Published: July 2021

We present the case, with tomographic three-dimensional reconstructions, of an adult patient affected by congenital absence of one pulmonary valve cusp with completely normal morphology of the other two cusps.
Awareness of and reactions to health and environmental harms of red meat among parents in the United States
Authors: Grummon Anna H , Goodman Dina , Jaacks Lindsay M , Taillie Lindsey Smith , Chauvenet Christina A , Salvia Meg G , Rimm Eric B
Published: July 2021

Objective:

Evidence of the health and environmental harms of red meat is growing, yet little is known about which harms may be most impactful to include in meat reduction messages. This study examined which harms consumers are most aware of and which most discourage them from wanting to eat red meat.

Design:

Within-subjects randomised experiment. Participants responded to questions about their awareness of, and perceived discouragement in response to, eight health and eight environmental harms of red meat presented in random order. Discouragement was assessed on a 1-to-5 Likert-type scale.

Setting:

Online survey.

Participants:

544 US parents.

Results:

A minority of participants reported awareness that red meat contributes to health harms (ranging from 8 % awareness for prostate cancer to 28 % for heart disease) or environmental harms (ranging from 13 % for water shortages and deforestation to 22 % for climate change). Among specific harms, heart disease elicited the most discouragement (mean = 2·82 out of 5), followed by early death (mean = 2·79) and plants and animals going extinct (mean = 2·75), though most harms elicited similar discouragement (range of means, 2·60–2·82). In multivariable analyses, participants who were younger, identified as Black, identified as politically liberal, had higher general perceptions that red meat is bad for health and had higher usual red meat consumption reported being more discouraged from wanting to eat red meat in response to health and environmental harms (allP< 0·05).

Conclusions:

Messages about a variety of health and environmental harms of red meat could inform consumers and motivate reductions in red meat consumption.
A Pragmatic Approach to Carbon Border Measures
Authors: Meyer Timothy , Tucker Todd N.
Published: July 2021

This article offers the justification for a type of carbon customs union in which countries with a diverse range of high-ambition domestic climate measures would adopt a common external tariff on carbon intensive imports from countries outside the union. We explain why any pragmatic approach to carbon border measures (CBMs) is likely to create problems under prevailing interpretations of the World Trade Organization's (WTO) primary rules. Given the urgency of the climate crisis and the fact that the legality of a CBM – no matter how designed – will be a question of first impression for any WTO dispute panel, WTO consistency should take a backseat to considerations of domestic legal and political feasibility in designing a CBM. Instead of trying to fit a CBM into current understandings of WTO rules, WTO members should renegotiate WTO rules to permit a range of aggressive, but likely trade-restrictive, decarbonization measures. Having said that, we also recognize that WTO negotiations may take longer than optimal from a decarbonization standpoint. We therefore suggest an approach that would allow WTO members to take advantage of flexibilities that existing WTO rules afford.