bluuebunny/crossref_metadata_2025 huggingface dataset:
ESG–CFP Linkages: A Review of Its Antecedents and Scope for Future Research
Authors: Singh Aanchal , Singh Prakash , Shome Samik
Published: May 2022

The last two decades have seen a gradual shift in the reporting practices of the corporate sector across the globe. Besides reporting the standard financial statements, there is increased emphasis on qualitative reporting particularly issues related to governance, sustainability and society, popularly referred to as environmental, social and governance (ESG) reporting ( Griffin & Sun, 2018 ). In this regard, sustainability issues are being more aggressively addressed by the firms. This study aims at identifying and empirically examining the antecedents that influence the relationship between ESG disclosures of organisations and its corporate financial performance (CFP). The study uses a sample of BSE-200 companies and employs multiple regression technique to ascertain the ESG–CFP relationship. The results obtained show that ESG and CFP are negatively related, and the control variables have a significant impact on this association. The study provides insights from the perspective of an emerging economy and contributes to both the managerial decision-making and policy formulation. It also paves the way for future research.
Xylometazoline Induced Isolated Left Medial Cerebellar Peduncle Infarct: A Rare Case Report
Authors: Bhardwaj Ankit , Mukherjee Shoma , Roy Vandana
Published: May 2022

Xylometazoline, a sympathomimetic available as over the counter drug, acts as a nasal decongestant and has been reported as an independent risk factor for hemorrhagic and ischemic stroke. The chronic use of xylometazoline leads to either increased release of more potent vasoconstrictor norepinephrine in the presynaptic region, or acts directly on central adrenoreceptors which leads to dysfunction resulting in chronic progressive vasculopathy that manifests as an ischemic stroke. Sympathomimetics also activate 12-lipoxygenase pathways which induce proliferation and migration of vascular smooth muscle cells. 12-lipoxgenase also plays a significant role in regulating the degree and stability of platelet activation, as its activation significantly strengthens platelet activation and uncontrolled platelet activation, which may lead to myocardial infraction and stroke. The present case reports a rare case of young adult suffering from isolated left medial cerebellar peduncle infarct related to the chronic use of xylometazoline. Acute cerebellar stroke is rare, especially in young adults and represent only 3% of total ischemic and hemorrhagic strokes. Clinical symptoms, patient age at the onset of stroke, and lesion size had no significant effect on the clinical outcome. Symptoms are frequently underestimated and misdiagnosed which further lead to serious complications and poor functional outcomes.
Systematic Review and Meta-Analysis Comparing the Safety of Natalizumab, Ocrelizumab, and Alemtuzumab in Treating Relapsing–Remitting, Primary Progressive, and Secondary Progressive Multiple Sclerosis
Authors: Raina Pooja , Basu Somnath , Goyal Ramesh K , Sahoo Pravat K , Mathur Rajani
Published: May 2022

Three monoclonal antibodies—natalizumab (NTZ), ocrelizumab (OCR), and alemtuzumab (ALM)—are the mainstays for the treatment of both relapsing and progressive forms of multiple sclerosis (MS). Here, their safety in patients with MS is analyzed and compared for rational use, especially during the COVID-19 pandemic. All clinical studies published between 2016 and 2020 with the primary outcome of the occurrence of adverse events (AEs) with the use of NTZ, OCR, and ALM in the treatment of MS were systematically searched in the PubMed database. In this review, the percentage of patients reporting AEs was calculated and compared. The most common AEs associated with the use of NTZ, OCR, and ALM were infection and infestation. The percentage of patients reporting urinary tract infection, upper respiratory tract infection, and herpes was 16% using natalizumab, 7% using natalizumab and ocrelizumab, and 2% with ocrelizumab, respectively. The most common AEs, such as rashes, pyrexia, and influenza, were reported with ocrelizumab and alemtuzumab. Additionally, alemtuzumab was associated with immune thrombocytopenia (2%), respiratory infections (7%), and thyroid dysfunction (43%). All these data outcomes show that of the three monoclonal antibodies, natalizumab and ocrelizumab were associated with a reduced incidence of adverse events, making them a safer choice for MS.
Predictors of Pharmacotherapy and Quality of Life Among Patients With Diabetic Foot Syndrome: A Cross-Sectional Study from a Tertiary Care Hospital in India
Authors: Pasangha E. , George B. , Bhuvana K. B. , Padmini D.
Published: May 2022

Objective:

To assess the patterns and predictors of pharmacotherapy and QOL in DFS patients in an Indian tertiary care hospital.

Methods:

A cross-sectional study was conducted among inpatients with DFS. Data on sociodemographic and clinical factors, pharmacotherapy, clinical outcomes, and QOL were analyzed using the chi-squared test, independent sample t-test, and binary logistic regression.

Results:

We screened 3284 inpatients and included consecutive 87 (2.7%) DFS patients. The mean age was 56.08 ± 11.05 years, with a male preponderance (75.8%). Mean HbA1c was 9.9 ± 2.483. About 75% of patients received insulin, and polypharmacy was noticed in 82.7%. About 67.8% of DFS patients had other vascular complications of diabetes, with diabetic retinopathy being the most common in 89%. Amputations were noticed in 32.1% of patients. Overall, poor QOL was seen in 79.3% of patients. The mean scores for different domains were as follows: physical, 41.51 ± 14.15; psychological, 42.90 ± 11.16; social relationships, 43.06 ± 19.36; and environment, 47.17 ± 13. The presence of complications from diabetes was a significant predictor of the utilization of antihypertensives (OR: 2.92, CI [1.09, 7.79], P = 0.03) and poor QOL (OR: 4.54, CI [0.965, 21.41], P = 0.05).

Conclusion:

DFS patients in this study were found to be younger with poor glycemic control and other vascular complications of diabetes. The presence of other complications of diabetes in DFS patients was found to be a predictor of pharmacotherapy and poor QOL.
Bullous Drug Reaction with Dipeptidyl Peptidase-4 (DPP-4) Inhibitors
Authors: Geetha K. , Puja
Published: May 2022

Hypoglycemic drugs in the dipeptidyl peptidase-4 (DPP-4) inhibitor class are used as a second-line treatment for type 2 diabetes mellitus. With DPP-4 inhibitors, there have been a few reports of cutaneous side effects such as bullous response, fixed drug eruption, and photosensitivity. There is no definitive pathophysiology for the above mentioned allergic reactions. Sitagliptin phosphate belongs to the DPP-4 inhibitor class. This is a case report of a sitagliptin-induced bullous drug reaction manifesting three weeks after starting therapy. He had bullous pemphigoid-like eruptions all over the body. The patient showed improvement once sitagliptin was discontinued alon with oral and topical steroid treatment.
Antivitamins: A Silver Lining in the Era of Antimicrobial Resistance
Authors: Mahwish Nayesha , Bairy Laxminarayana Kurady , Srinivasamurthy Sureshkumar
Published: May 2022

Antivitamins are compounds that negate the biological effects of vitamins. They have been successfully exploited for the development of various classes of drugs. In the early 19th century, the antifolate prontosil was developed for the treatment of puerperal fever. Since then, numerous other antifolates have been used to treat a wide range of infections. Antifolates, such as methotrexate, are potent anticancer agents and antivitamin K, such as warfarin, are used as anticoagulants. Despite several years of research, most antivitamin-based drugs are limited to vitamin K and B9, and the development of antagonists for other vitamins is still in the nascent stage. In the era of antimicrobial resistance, antivitamins can be considered as a promising alternative to develop newer antimicrobials and are worth exploring further. This review discusses key antivitamins at different stages of development which have potential utility as antibiotic drug candidates. The summary of studies of antivitamins in clinical development is also narrated.
A Randomized Double-Blind Comparative Study of Efficacy and Safety Between Low-Dose Etoricoxib and Ibuprofen Coadministered with Low-Dose Paracetamol for Dental Pain
Authors: Saroj Kothari , Haresh Bansal , Yogendra Paharia
Published: May 2022

Objective:

To study the safety and efficacy of low-dose etoricoxib and low-dose paracetamol versus ibuprofen and low-dose paracetamol treatments in patients who experienced acute pain after tooth extraction.

Methods:

A total of 80 patients were recruited and randomized to two study groups, i.e., EP and IP. Group EP received etoricoxib 30 mg once a day and add-on paracetamol 325 mg eight-hourly, and Group IP received ibuprofen 400 mg and paracetamol 325 mg eight-hourly for three days. The analgesic efficacy was assessed by a visual analog scale, pain relief score, and global evaluation score. Patients were assessed at 0, 6, 24, 48, and 72 h. Safety was assessed by the patient’s estimation of the severity of adverse drug reactions using a 3-point scale and the type of adverse drug reactions reported by the patients after 72 h.

Results:

Mean pain intensity reduction, mean pain relief score, and global evaluation score all showed better analgesic efficacy results in Group EP as compared to Group IP but were not significant ( P > 0.05) at 6, 24, 48, and 72 h, respectively. No patient had reported any serious adverse drug reaction in both the groups. Mild to moderate adverse reactions were reported in 20% cases in the IP group and 10% cases in the EP group; however, the incidence of GIT intolerance was seen in 17.5% of the cases in the IP group and none in the EP group.

Conclusion:

Low-dose etoricoxib with low-dose paracetamol has comparable analgesic efficacy with better safety than therapeutic dose ibuprofen and low-dose paracetamol.
Integration of alcohol and drug nurses into a mental health unit
Authors: Solar Ann M , Bennett Kellie , Hulse Gary
Published: May 2022

Objective

Test whether extra time with alcohol and drug nurses for inpatients at a Mental Health Unit (MHU) reduces post-discharge mental and co-occurring alcohol and drug problems and increases engagement in alcohol and drug treatment more than a Brief Information Pack (BIP).

Method

Single blind randomised control trial in block design compared two alcohol and drug nurse delivered interventions over 6 months post-discharge using the Alcohol Use Disorders Identification Test (AUDIT) and Brief Symptom Inventory index of overall psychological distress Global Severity Index (GSI).

Results

Alcohol and drug nurse delivered BIP was associated with a statistically significant reduction in AUDIT measured alcohol use for the highest follow-up score across the 6-month post-discharge period, n = 20, t = 2.24, p = 0.037, d = 0.50 and for the extra time intervention, n = 11, t = 2.51, p = 0.031, d = 0.76.

Conclusions

MHUs may benefit from the integration of alcohol and drug nurses with community alcohol and drug treatment experience.
High-grade Endometrial Stromal Sarcoma: Morphologic and Clinical Features, the Role of Immunohistochemistry and Fluorescence in Situ Hybridization in Diagnosis
Authors: Alkanat Nazli Eylem , Uner Aysegul , Usubutun Alp
Published: May 2022

Introduction. High-grade endometrial stromal sarcomas (HGESS) are rare malignant mesenchymal tumors of the uterus with aggressive poor clinical outcome, which frequently exhibit YWHAE::NUTM2 and ZC3H7B::BCOR fusions. In this study, we aimed to investigate HGESSs with YWHAE and BCOR translocations through our archive materials, and to identify morphological, immunohistochemical and molecular features of these tumors. We also assessed the diagnostic value of BCOR immunohistochemistry (IHC) in HGESSs, low-grade endometrial stromal sarcomas (LGESS) and uterine leiomyosarcomas. Methods. One hundred fifty-one uterine sarcomas diagnosed between 2000-2019 were reevaluated, and tumors of 39 patients with specific features were included in the study. Fluorescence in situ hybridization (FISH) studies using YWHAE and BCOR break-apart probes and BCOR IHC were performed. BCOR IHC was also performed in 20 leiomyosarcomas and 19 LGESSs. Results. In six HGESSs, translocations involving YWHAE or BCOR were detected. Five tumors showed high-grade morphology and revealed YWHAE translocation. One HGESS with myxoid morphology revealed BCOR translocation. In immunohistochemistry, three (3/4) YWHAE translocated HGESSs showed BCOR expression. However, the BCOR translocated HGESS was BCOR negative. The study showed that all LGESSs were immunohistochemically negative with BCOR. Although 15% (3/20) leiomyosarcomas reveal focal weak-moderate BCOR expression. Conclusion. BCOR IHC is a useful marker to distinguish LGESS from HGESS. A small percentage of uterine leiomyosarcomas reveal BCOR expression; however, it is not as diffuse and strong as in HGESSs. Strong and diffuse BCOR IHC expression is highly suggestive for HGESS. The diagnosis of HGESS should be supported by molecular studies such as FISH.
A Qualitative Exploration of Sleep-Related Sexual Interests: Somnophilia and Dormaphilia
Authors: Deehan Elizabeth T. , Bartels Ross M.
Published: May 2022

Somnophilia is an under-researched paraphilia. Consequently, there are discrepancies in its definition and conceptual understanding. Also, literature regarding the sexual interest in being asleep during sexual activity (dormaphilia) is even more limited. As such, there is a need to understand these paraphilias more deeply. This study recruited 232 participants online to discuss the content, origin, sexual appeal, emotional appraisal, and behavioural enactment of their somnophilic and dormaphilic interests and fantasies. A Thematic Analysis led to the identification of four main themes: (1) Relevance of Sleep State; (2) Roles within Sleep Sex; (3) Enactment of Sleep Paraphilia and (4) Lack of Consent and Awareness. These four themes spanned across both those reporting somnophilic and dormaphilic fantasies. The Discussion explores the multi-faceted nature of the interests, and implications for the understanding of somnophilia and dormaphilia. This study provides the first qualitative exploration of sleep-related paraphilias, opening avenues for future research and practice.
Effects of the Discharge Education Program on Family Caregivers Caring for Patients on Mechanical Home Ventilation in Korea: A Pilot Test
Authors: Kim Hyang Sook , Kim Gwang Suk , Lee Hyangkyu , Choi JiYeon , Kim Young Sam , Oh Eui Geum
Published: May 2022

Patients on home ventilators rely on mechanical ventilation until their death; hence, family caregivers should perform additional caregiving, including tracheostomy, equipment management, and positive pressure ventilation by ambu-bag in emergencies. Therefore, a systematic discharge education program and evaluation of actual caregiver performance are necessary for safe home management. The program consists of suction and tracheostomy management, home ventilator management, emergency management, fundamental caregiving, and video material. To test clinical validity, family caregivers of patients about to be discharged to their homes from S hospital in Seoul, Korea, were selected by convenience sampling with a non-equivalent control group design. Of 18 participants, one refused, one died, and two became unstable after their agreement; therefore, 14 participants were finally included. To compare caregiving performance scores between the groups, we ran repeated measures ANOVA. Intergroup and period interaction of suction ( F = 6.08, p = .001) and tracheostomy management ( F = 3.00, p = .038) crucial for airway management, showed significant statistical differences. In short, the intervention group showed a faster increase in suction and tracheostomy management than the control group. Home ventilator management ( F = 22.53, p < .001), emergency management ( F = 12.01, p < .001), and fundamental caregiving ( F = 7.88, p < .001) showed significant differences within the group regarding the period. According to the results of the clinical validity test, the discharge education program increased the family caregiver’s suction and tracheostomy management performance scores. Further research is needed to demonstrate long-term effects of the program with a larger sample.
“I Am a Parrot”: Literacy Ideologies and Rote Learning
Authors: Bhattacharya Usree
Published: May 2022

Widely prevalent in a variety of educational contexts around the world, rote learning practices entail repetition techniques to acquire new knowledge. These practices have long been critiqued because of the emphasis on recall rather than deep understanding. Less attention has been directed, however, at the literacy ideologies underpinning such practices: specifically, how such practices shape what students perceive as learning and how they see themselves as learners. In order to examine this, I draw on data from an 8-year investigation into the language and literacy socialization of six young boys who lived at an orphanage and attended a village school in suburban New Delhi. In addition to uncovering ideologies related to rote learning practices, I show how students acted as “bad subjects” by discursively resisting socialization into passive learner subjectivities. The findings are then related to the reproduction of inequality within the educational system through literacy practices.
Urban-Rural Differences in Children’s and Adolescent’s Physical Activity and Screen-Time Trends Across 15 Years
Authors: Nigg Carina , Weber Christoph , Schipperijn Jasper , Reichert Markus , Oriwol Doris , Worth Annette , Woll Alexander , Niessner Claudia
Published: May 2022

Background

Urban and rural areas have been experiencing major demographic and structural changes, characterized by an aging population in rural areas and a growth of cities in number and size. However, it is poorly researched how children’s physical activity and screen time developed in urban and rural areas. To address this deficit, we investigated physical activity and screen-time trends in Germany’s pediatric population across four urbanicity levels (rural, small town, medium-sized town, city).

Method

We obtained weighted data at three cross-sectional timepoints between 2003 and 2017, representative for Germany’s child and adolescent population. Physical activity and screen time were self-reported. We analyzed trends using a structural equation modeling framework for the overall sample and calculated interactions between the trends and age and gender, respectively.

Results

In total, 12,161 children and adolescents between 4 and 17 years participated in the study. Children and adolescents in rural areas experienced a downward trend in total physical activity. Outdoor play and leisure-time physical activity decreased across all areas, with the strongest decline in rural areas. Computer and gaming time increased across all areas except for cities, with the sharpest increase in rural areas. The decline in outdoor play and the incline in computer and gaming time were driven by adolescents. Females showed stronger increases in computer and gaming time than males.

Conclusion

Our findings suggest that in a representative sample of children and adolescents in Germany, detrimental trends in children’s physical activity and screen time occur at a higher rate in rural areas compared with urban environments. This provides critical information for health policy: While all children and adolescents should be targeted for physical activity promotion, a special focus should be on tailoring interventions for rural areas to prevent and mitigate inequalities in physical activity across urban and rural areas.
Role of Perinatal Biological Factors in Delayed Lactogenesis II Among Women With Pre-pregnancy Overweight and Obesity
Authors: Ren Ziqi , Zhang Aixia , Zhang Jingjing , Wang Rui , Xia Haiou
Published: May 2022

Background

Pre-pregnancy overweight and obesity are negatively associated with delayed onset of lactogenesis II (OL), but the mechanisms by which these conditions affect OL are still unclear.

Objectives

To identify biological factors related to pre-pregnancy overweight/obesity and determine whether these biological factors were associated with delayed OL in this population.

Methods

In this prospective observational study, we assigned 72 primipara to a pre-pregnancy overweight/obese group ( n = 36) and a normal-weight group ( n = 36). Blood samples were collected at 37 w of gestation and 48 h postpartum and assayed for levels of the following hormones: leptin, insulin, estradiol, prolactin (PRL), progesterone, and oxytocin. The primary outcome was timing of OL, estimated by maternal perception of breast fullness. We used linear-regression analysis to determine associations between hormones and delayed OL.

Results

Sixty-three participants (87.5%) had complete data. OL occurred later in overweight/obese than in normal-weight women ( p < .001). Compared with the normal-weight group, the overweight/obese group showed higher leptin levels at both times of observation and exhibited a slower drop in estrogen concentrations from 37 w of gestation to 48 h postpartum (all p < .05). After adjusting for confounding factors, leptin concentrations in late pregnancy and the magnitudes of decline in estrogen concentrations at 48 h postpartum were correlated with OL.

Conclusion

Women who were overweight/obese before pregnancy had elevated leptin levels in late pregnancy and a delayed decline in estrogen concentrations at 48 h postpartum. Both of these phenomena were related to delayed OL in this population.
Comparison of brain-derived neurotrophic factor among subtypes of exudative age-related macular degeneration
Authors: Park Keon Woo , Joo Jung Yeon , Kim Seong Taeck
Published: May 2022

Purpose

To compare the levels of brain-derived neurotrophic factor (BDNF) in serum and aqueous humor (AH) in eyes with typical neovascular age-related macular degeneration (tAMD), polypoidal choroidal vasculopathy (PCV), and retinal angiomatous proliferation (RAP).

Methods

This prospective study included 20 patients with tAMD, 20 patients with PCV, 20 patients with RAP, and 20 healthy controls. BDNF levels in the serum and AH were assessed using enzyme-linked immunosorbent assay.

Results

Serum and AH BDNF levels were significantly lower in the age-related macular degeneration groups (tAMD, PCV, and RAP) than in the control group ( p < 0.05). There was no significant difference in the mean BDNF levels in the serum and AH among the different nAMD subtypes ( p = 0.538).

Conclusions

We confirmed that serum and AH BDNF levels were independent of the nAMD subtype.
A model for effective partnership working to support programme evaluation
Authors: Fynn Judith F. , Milton Karen , Hardeman Wendy , Jones Andy P.
Published: May 2022

The use of multi-agency partnerships, including research-practice partnerships, to facilitate the development, implementation and evaluation of public health interventions has expanded in recent years. However, gaps remain in the understanding of influences on partnership working, and their capacity to facilitate and use evaluation, as well as the characteristics which lead to partnership effectiveness. We applied qualitative methods to explore experiences of stakeholders who were involved in partnerships to deliver and evaluate a national physical activity programme. We combined thematic and network analysis, and drew on concepts of evaluation use, knowledge exchange and organisational systems to interpret our findings and develop a conceptual model of the relationships between partnership characteristics and processes. Our model identifies key partnership characteristics such as high levels of engagement, regular communication and continuity. Furthermore, it highlights the importance of implementing organisational structures and systems to support effective partnership working, knowledge exchange and capacity building.
Performing the disaster genre? TV journalism, disruptive factors and community challenges in the reporting of the UK Grenfell Tower block fire
Authors: Matthews Julian
Published: May 2022

News coverage of national disasters holds the potential to evoke unique moral sentiments and political reactions. Often, however, we learn that the common use of elite political actors’ consensual commentary by journalists serves to politically appropriate such events or render mute their potential. This paper explores a challenge to this observed authority skew in the performance of TV journalism (BBC, ITN, Channel 4 and Channel 5) while covering the aftermath of the Grenfell Tower block fire. The analysed reporting shows that the presence of (i) disruptive geography (ii) disruptive expertise and (iii) disruptive commentary challenge the reproduction of a traditional ‘reporting template’ and its inscribed authority skew. Combined, such ‘disruptive factors’, it is reasoned, enable opportunities for challenger voices to appear in number, and therein direct criticisms of both neglect and inaction and even to reflect on the state, race and poverty and incite thereafter an elite political apology.
Positioning five-star hotels in city destinations: The case of Istanbul, Turkey
Authors: Şanlıöz-Özgen Hanım Kader , Kozak Metin
Published: May 2022

Destinations and hotel businesses take advantage of many benefits of the online world. Extensive qualitative (review texts) and quantitative (review scores and room rates) data sources enable them to assess their positions through the eyes of their customers. The aim of this study is to propose a method focusing on customer reviews and rates in order to help hotel businesses with assessment of their positioning strategies. The dataset included a selection of five-star hotels in Istanbul, a city destination of Turkey. Room rates and the findings from a thematic narrative analysis of TripAdvisor reviews from a cognitive and experiential perspective were combined to create a position map. The findings extend traditional classification systems and reveal three competitive groups of five-star hotels with specific attributes in a city destination. Other findings offer some insight for hotel and destination managers, enabling them to evaluate the performance of positioning strategies of five-star hotels in the market.
Narrating from landscape in Andean archaeology: The problem with the suni natural region
Authors: Ramón Gabriel , Bell Martha G
Published: May 2022

Archaeologists use the landscape to explain the past, often referring to traditional or indigenous knowledge to better understand that landscape. But how is this analogical process performed, and how is indigenous knowledge understood and recorded? This article examines Peruvian geographer Javier Pulgar Vidal’s concept of suni—a term with several definitions in Aymara and Quechua, but which was transformed by Pulgar Vidal into a “Natural Region,” in other words a meaningful portion of the landscape—as an entry point into this broader issue. Suni is important because it is a poorly defined part of a wider Andean landscape model supposedly based on indigenous knowledge and because it is commonly used by archaeologists to explain precolonial land use and landscapes. Through analysis of the creation and application of suni, we define major challenges faced by archaeologists when interpreting sites and materials in landscape perspective and present suggestions for moving forward.
Intercultural care for people of migrant origin with dementia – A literature analysis
Authors: Monsees Jessica , Schmachtenberg Tim , René Thyrian Jochen
Published: May 2022

Background

Close to 12 million people of migrant origin who are 65 years or older live in different European countries. In the European Union (EU) and the European Free Trade Association (EFTA) countries, approximately half a million are estimated to have dementia. This rate is expected to increase in the coming decades. People of migrant origin who develop dementia and their families face challenges people without migration backgrounds do, but due to cultural differences, additional challenges may arise. There is an increasing need for interculturally sensitive care. There is research on certain aspects of intercultural care and this study will be a comprehensive summary of current topics in intercultural care.

Research question

What factors of intercultural care for people of migrant origin with dementia can be identified? What requirements and aspects are necessary to ensure intercultural care?

Method

A systematic literature analysis in the databases PubMed, PsycInfo and Psychology and Behavioural Sciences Collection was conducted.

Findings

Thirty-nine articles were eligible for analysis. Enhancement in the areas diagnostics, education and information, healthcare services and healthcare professionals to ensure intercultural care is needed.

Discussion

Current evidence supports the need for (a) thorough education of people of migrant origin with dementia, their families and healthcare professionals, (b) collaborations among everyone involved, (c) embracing different cultures in healthcare services, (d) the implementation of a care navigator functioning as a contact person and connecting all relevant parties with one another and (e) dementia testing suitable to the target group to ensure culturally sensitive and appropriate care for people of migrant origin with dementia and their families.
“If You Don’t Fight Like Hell, You’re Not Going to Have a Country”: An Intersectional Settler Colonial Analysis of Trump’s “Save America” Speech and Other Messages of (Non)belonging
Authors: Jordan Lorien S. , Dykes Dewey
Published: May 2022

Donald Trump turned the presidency into a live-action reality television series comprising a chaotic blend of televised and tweeted intrigue. The nation’s collective anxiety coalesced in a nationalistic, authoritarian denouement on January 6, 2021. During Trump’s speech at the Save American Rally, he returned to familiar themes, telling the story of a ravaged America and his role as its victimized hero. As Trump concluded his speech urging supporters to “fight like hell,” rioters assailed the U.S. capitol revealing the violence of colonial invasion. To understand and, thus, respond to the insurrection, we must first recognize the dominant structures that create the conditions of its perpetration and excusal. This intersectional analysis addresses the colonial impulse for violent exclusion through the interpretive framework of settler colonialism. Examining four interlocking themes, we incorporate historical and contemporary popular culture rhetorical devices to triangulate our findings. We illustrate how social identity and settler colonialism occur in popular culture at the intersections of American, Christian nationalism, racialization, hetero-genderism, and ableism. Overall, our analysis explores how Trump prepared his base through years of cultural manipulation, promoting a populist, White vision of the world with Trump symbolic of its savior. To subvert these exploitations, we must participate in their deconstruction to destabilize the power of colonial institutions.
Unilateral Modified Posterior Lumbar Interbody Fusion Combined With Contralateral Lamina Fenestration Treating Severe Lumbarspinal Stenosis: A Retrospective Clinical Study
Authors: Xue Yulun , Li Suoyuan , Wang Yefeng , Zhang Hong , Cheng Liang , Wu Yinghui , Wang Qiang , Wang Donglai , Zou Tianming , Shen Jun
Published: May 2022

Study design: Retrospective study. Objectives: The traditional PLIF is routinely utilized in severe lumbar spinal stenosis to relief the nerve compression. Nevertheless, the removal of posterior tension-band structure and the denervation and atrophy of the paraspinal muscle affect the clinical efficacy. Therefore, unilateral modified PLIF combined with contralateral fenestration was performed to overcome above-mentioned drawbacks. Methods: 32 modified PLIF and 33 traditional PLIF cases were retrospectively included. Operation time, length of stay (LOS) and blood loss were recorded. VAS of low back pain and leg pain, ODI and Sf-36 score including physical function and body pain were assessed. Fusion rate, lumbar lordosis (LL), intervertebral angle (IVA) and intervertebral height index (IHI) were evaluated radiologically. Results: Modified group possessed less blood loss, shorter operation time and less LOS. Compared with traditional group, the VAS of back pain was lower at 6 months postoperatively ( P < .05) and the ODI score was lower at 3 months postoperatively ( P < .05) in modified group. Modified group exhibited better physical function 3 months postoperatively and lower body pain 6 months postoperatively in Sf-36 score ( P < .05). No statistic difference in LL, IVA, IHI and fusion rate were observed between both groups. Conclusions: Our modified PLIF combining with contralateral fenestration procedure exhibited particular advantages in comparison to traditional PLIF. The preservation of posterior tension-band structure facilitates to less low back pain, low complication rate and early functional recovery.
Robotic versus Laparoscopic Total Mesorectal Excision Surgery in Rectal Cancer: Analysis of Medium-Term Oncological Outcomes
Authors: Li Jing-jing , Zhang Zhi-bo , Xu Shi-yun , Zhang Cheng-ren , Yang Xiong-fei , Duan Yao-xing
Published: May 2022

Background. Robotic systems can overcome some limitations of laparoscopic total mesorectal excision (L-TME), thus improving the quality of the surgery. So far, many studies have reported the technical feasibility and short-term oncological results of robotic total mesorectal excision (R-TME) in treating rectal cancer (RC); however, only a few evaluated the survival and long-term oncological outcomes. The following study compared the medium-term oncological data, 3-year overall survival (OS), and disease-free survival (DFS) of L-TME and R-TME in patients with rectal cancer. Methods. In this retrospective study, records of patients (patients with stage I-III rectal cancer) who underwent surgery (127 cases of L-TME and 148 cases of R-TME) at the Gansu Provincial Hospital between June 2016 and March 2018 were included in the analysis. Kaplan-Meier analysis evaluated the 3-year OS and DFS for all patients treated with curative intent. Results. The conversion rate was significantly higher, and the postoperative hospital stay was significantly longer in the L-TME group than in the R-TME group (all P<.05). Major complications were significantly lower in the robotic group (P<.05). The 3-year DFS rate (for all stages) was 74.8% for L-TME and 85.8% for R-TME ( P = .021). For disease stage III, the 3-year DFS and OS were significantly higher in the R-TME group ( P<.05). Conclusion. R-TME can achieve better oncological outcomes and is more beneficial for RC patients compared with L-TME, especially for those with stage III rectal cancers. Nevertheless, further randomized controlled trials and a longer follow-up period are needed to confirm these findings.
Vitamin B12 and Plant-Predominant Diets
Authors: White Nicole D.
Published: May 2022

Vitamin B12 deficiencies are common in individuals consuming plant-predominant diets, including those who consume diary and/or eggs. Deficiencies can lead to megaloblastic anemia and peripheral neuropathy, among other multi-system manifestations. The prevalence, assessment and prevention of vitamin B12 deficiency in patients following plant-predominant diets will be discussed.
Flow diverter retreatment for intracranial aneurysms: A meta-analysis of efficacy and feasibility
Authors: Lee Irene (Tai-Lin) , Kao Yung-Shuo , Lai Yen-Jun , Yen Ho-Hsian
Published: May 2022

Background

Recurrent intracranial aneurysm carries a risk of rupture and retreatment is often necessary. However, there is no consensus on the best retreatment modality of choice. Flow diverter has emerged as a promising option for this population in recent years. Given its high cost, patient selection to optimize outcomes is very important.

Purpose

To identify patient factors predisposing to failure of flow diverter retreatment.

Method

We conducted a systematic search on PubMed, Cochrane Library, Embase, Ovid/Medline, and ClinicalTrial.gov from 2000 to 2021. Studies regarding flow diverter retreatment of recurrent aneurysms were analyzed if they meet the inclusion criteria.

Results

A total of twenty-six studies were identified. Among 374 patients retreated with flow diverters, about 0.86 [0.81; 0.92] were successfully occluded and only 0.06 [0.02; 0.10] had unfavorable neurological outcomes. Major complications included intracranial hemorrhage (n = 7), ischemic stroke or thromboembolic event (n = 12), and death (n = 2). In-stent stenosis was reported in 10 of the cases. Saccular aneurysms are associated with a higher occlusion rate while aneurysm location, size, status, and prior treatment modality have no significant impact on retreatment efficacy.

Conclusions

We demonstrated that flow diverter is an effective retreatment strategy except in patients with non-saccular aneurysms. It should be considered as a first-line option for patients with recurrent intracranial aneurysm.
Percutaneous transosseous embolization of a diploic vein arteriovenous fistula with intracranial and extracranial shunting
Authors: Noufal Mazen , Liang Conrad , Chhabra Vaninder
Published: May 2022

Arteriovenous fistulae of the diploic veins are extremely rare. 1 Transarterial- and transvenous embolization have been employed in endovascular treatment. 2 – 7 We describe a novel treatment technique in which percutaneous transosseous embolization was performed to treat an extensive diploic vein arteriovenous fistula in the sphenoid bone with a 5 -cm venous varix. Numerous branches of the internal and external carotids fed the fistula with extracranial and intracranial shunting including cortical venous reflux. Safe transarterial embolization was inadequate. Transvenous access into the diploic venous varix through emissary veins was not successful. An 18-G needle was used under fluoroscopy to access the venous varix through the thinned outer table of the sphenoid greater wing. Brainlab navigation system was used to pre-study needle's insertion point and trajectory. Uneventful coil and Onyx embolization was performed.

Educational message

Transosseous embolization of diploic vein arteriovenous fistula is feasible when necessary in select cases.
Verification of software-based preoperative simulation of flow diverters in clinical cases
Authors: Wang Yixuan , Yang Xinjian , Zhu Wei , Wang Xinlan , Yao Yangyang , Lu Wangsheng , Yang Guangming , Qin Lan , Liu Jian , Li Miao
Published: May 2022

Objective

The authors sought to verify the use of a preoperative simulation software for the treatment of intracranial aneurysms using flow diverters (FDs) based on three-dimensional rotational angiography (3DRA) data.

Methods

Based on 3DRA data, the preoperative simulation software (UKNOW) was used to simulate the deployment of virtual FDs. The length and dimensions of virtual and real devices were compared. The deployment plan recommended by the UKNOW software was preliminarily used to complete implantations in the real world. During the experiment, experienced neurointerventional experts were responsible for supervising and judging information such as the length, dimension, and deployment location of the FDs.

Results

This study retrospectively analyzed the data of 29 patients who received FD treatment. There was no statistical difference between the length of the real device and the virtual device ( p = 0.6). The dimensions of FDs recommended by the software were consistent with the dimensions used in 24 out of the 29 real cases. In four of the remaining five cases, neurointerventional experts found that the FD dimensions recommended by the software were superior to those were actually used. Thus, the accuracy rate for FD dimension recommendations by the UKNOW software was 96.6% (28/29). Procedures performed in five cases using deployment plans recommended by the UKNOW software all achieved good postoperative results; the deployment positions of the device were reasonable, and all devices showed good wall adherence.

Conclusions

UKNOW software could accurately simulate the length and deployment position of the real FDs and provide suitable device dimensions.
Intravascular lithotripsy for severely calcified carotid artery stenosis - A new frontier in carotid artery stenting?
Authors: Singh Jasmeet , Kuhn Anna Luisa , Massari Francesco , Elnazeir Marwa , Kutcher Roberto , Puri Ajit S.
Published: May 2022

Carotid stenosis due to severely calcified plaque can pose a significant therapeutic challenge. Extremely calcified scars/stenosis plaques can be challenging from an endovascular treatment perspective as severely calcified lesions are prone to technical failure, stent re-coil and restenosis. Intravascular lithotripsy, approved for treatment of severely calcified coronary lesions, can be used for breaking up the calcium build up in the intimal and medial layers of the vessel wall prior to stenting. This was designated as a breakthrough device innovation by the Food and Drug Administration. This new technique addresses the challenge of the disease without compromising patient safety during the procedure. We here report procedural set-up, execution and early patient follow up from our first use of this emerging technology in a neurointerventional practice setting.
Analysis and optimization of temperature field of high-speed permanent magnet motor
Authors: Hu Kai , Zhang Guangming , Zhang Wenyi
Published: May 2022

High-speed permanent magnet motor (HSPMM) has a wide application prospect in machinery, energy, and other industries. The temperature field of HSPMM was analyzed and optimized in order to reduce the operating temperature and improve the service life and efficiency. Two new methods were proposed to reduce the copper loss and iron loss. Response surface method was employed to improve permanent magnet parameters. The response surface results demonstrate that then factor A is 7.7 mm, factor B is 5.0 mm, and factor C is 134.9°, the core loss is minimum with 32.91 W. On the premise of comprehensively considering the thermal convection, conduction, and radiation effects, the equivalent thermal circuit model of HSPMM was creatively established. The theoretical analysis data show that the temperature of each position of the optimized motor is reduced by 8.2°C–10.2°C. In order to verify the correctness of the above theoretical analysis, a temperature measuring experiment was conducted. The temperature error between the measured data and the theoretical calculation data is acceptable, and the average error is only 4.01%. The research methods and conclusions can be widely extended to the temperature field optimization of other permanent magnet motors.
Phase inversion simulation of polymer PVDF membrane based on a fluid model
Authors: Fang Ping , Liu Kang , Shao Ruihua , Li Yan , Ji Wei , Yang Chaoyu
Published: May 2022

Based on the non-solvent-induced phase inversion (NIPS) membrane production process, we developed a model incorporating hydrodynamic effects and phase-field theory to simulate the phase separation process induced by concentration differences in polymer solutions. The influences of the initial polymer concentration and the composition of the coagulation bath on the film structure were studied. We found that the phase separation process starts from the top of the polymer solution layer and proceeds downwards in the layered structure. In the same system, as the initial PVDF concentration increases, the simulated morphology changes from a bi-continuous pattern to isolated droplets, thus determining the membrane morphology. Also, the validity of the model has been verified by corresponding experiments. Therefore, the model can be applied to other PVDF ternary membrane systems by modifying the material and its property parameters.
A modified progressive damage model for simulating low-velocity impact of composite laminates
Authors: Shao Jiaru R , Liu Niu , Zheng Zijun J
Published: May 2022

A modified progressive damage model is constructed to analyze the damage mechanics and damage development of composite laminates induced by low-velocity impact in this article. The damage modes are judged by the 3D Hashin failure criterion. A modified damage evolution model, which was constructed based on through-thickness normal strain component [Formula: see text], is implemented to describe progressive damage of composites. Cohesive elements with quadratic failure criterion and B-K criterion are applied to simulate the development of delamination. The 3D Hashin criterion and modified damage evolution model are coded in VUMAT and called in the ABAQUS/Explicit package. The damage distribution and mechanical behavior, including impactor energy, react force, displacement, predicted by numerical simulation are compared with the experimental data of different impact energies (7.35, 11.03, and 14.70 J). The numerical results and experimental data are in good agreement, which suggests that the modified damage evolution model is beneficial for studying the dynamic mechanical behavior during impact. Moreover, the influence of cohesive element thickness on numerical results is discussed. It is concluded that the cohesive element thickness should be adopted between 0.001 and 0.0075 mm.