bluuebunny/crossref_metadata_2025 huggingface dataset:
Determining the Ideal Substrate in Exposure Experiments for Ecotoxicology – a Metabolomics Approach
Authors: Sinclair Georgia May , Giannantonio Michela Di , Jones Oliver A.H. , Long Sara M.
Published: October 2021

It is crucial to understand the effects caused by experimental parameters, such as temperature; light availability; and food type that can interfere when determining a dose-response relationship in toxicology exposure experiments. Limiting variability is especially important when developing metabolite biomarkers of contaminant exposure since metabolomics is very sensitive to any internal and external factors that affect organism health and metabolic status. Ecotoxicologists are well aware of the importance of experimental design but the type of substrate used in exposure experiments is generally assumed to have no effect and is not assessed. This may not always be correct. Here we investigate the different metabolic changes in the freshwater crustacean, Austrochiltonia subtenuis to the heavy metal copper caused using three common substrate types, gauze; toilet paper; and cellulose. Each substrate type elicited a different metabolic response over the course of the experiment indicating substrate type affected the final results of the exposure test. Metabolites were assessed using Gas Chromatography-Mass Spectrometry. Several groups were shown to change including disaccharides, monosaccharides, fatty acids and their conjugates, and TCA cycle intermediates. The results illustrate that different metabolomic responses can occur from experimental design decisions previously thought not to have a significant effect. This may in turn affect policy decisions based on the results of the experiment. We propose that metabolomics can play an important part in the design of ecotoxicity tests and that all experimental parameters should be assumed to potentially have an effect until proved otherwise.
Complete chloroplast genome of Campsis grandiflora (Thunb.) Schum and systematical comparative analysis within the family Bignoniaceae.
Authors: Chen Haimei , Chen Zhuoer , Du Qing , Jiang Mei , Liu Chang
Published: October 2021

Background The plants in the Bignoniaceae have a wide distribution in the tropics and large populations around the world. However, the research information of Bignoniaceae is still scarce or even blank. To excavating the research information of Bignoniaceae plants and provide data support for the study of plant plastid genomes. Methods and results In this study, We have done a particular exploration of the chloroplast genome bioinformation of Campsis grandiflora. The chloroplast DNA of C. grandiflora was extracted, sequenced with HTS platform, assembled, and annotated with corresponding software. Results show that the complete chloroplast genome of C. grandiflora is 154,303 bp long, having a quadripartite structure with large single copy (LSC) of 85,064 bp and a small single copy (SSC) of 18,009 bp separated by inverted repeats (IRs) of 25,615 bp. A total of 110 genes in C. grandiflora is comprised of 79 protein-coding genes, 27 transfer RNA (tRNA) coding genes and 4 ribosomal RNA (rRNA) genes. The location and distribution of simple sequence repeats (SSRs) and long repeat sequences were determined. We finished the phylogenetic analysis based on homologous amino acid sequence among 45 species which derived from Bignoniaceae.Conclusions The chloroplast genomes have been used for molecular markers, species identification and phylogenetic studies. The outcome strongly supported that C. grandiflora and genus Incarvillea formed a cluster within Bignoniaceae. This study identified the unique characteristics of the C. grandiflora cp genome, which will provide a theoretical basis for species identification and biological research.
Community awareness of which seizure type should present to healthcare providers; a potential risk factor of the epilepsy treatment gap
Authors: Babiker Ismat , Elnaeim Mohamed K. , K.Elnaeim Awab
Published: October 2021

Objective: the objective of this study was to assess the awareness of the community in Sudan of which seizure type(s) should present to health care providers.Methods: This is a cross-sectional descriptive internet-based survey that was conducted in Sudan during the period from January to April 2018, using google forms. The survey consisted of demographic data (age, gender, educational level), a statement evaluating participants’ sources of obtaining information regarding epilepsy, a statement assessing awareness about the primary care provider for people with epilepsy (PWE), and a statement describing the symptomatology of different seizure types in simple Arabic, asking what description(s) participants thought should present to health care providers. We included participants residing in Sudan, and those with a college degree or higher education. Four hundred sixty-seven participants completed the survey.Results: 467 participants were included, of whom, 279 (60%) were females. The mean age of participants was 28 years. Two-thirds of participants obtained their information from non-scientific sources. 84% of the participants were aware that doctors are the primary health care providers for people with epilepsy.The majority (92.%) of participants were aware that patients with symptoms corresponding to the generalized tonic-clonic seizure description should present to doctors, compared with two-thirds of participants for focal seizure symptom description, and only 30.6 % of participants for absence seizure symptom description.Conclusion: This study demonstrated poor awareness about the necessity of presentation for focal and absence seizures. We hypothesize that this lack of awareness may contribute to the epilepsy treatment gap, and we recommend further studies to examine this hypothesis.
Sesquiterpene Lactones Isolated from Carpesium Abrotanoides L. by LC-MS Combined with HSCCC Inhibit Liver Cancer Through Suppression of the JAK2/STAT3 Signaling Pathway
Authors: Shen Bingbing , Yang Yupei , Wan Dan , Yu Huanghe , Cai Yuan , Wang Xionglong , Tang Daifeng , Tang Chunyu , Zhang Shuihan
Published: October 2021

Carpesium abrotanoides L. is rich in sesquiterpene lactones, the experiments of anti-tumor activity in vitro showed that total sesquiterpene lactone extracts exhibited the most cytotoxicity activities against HepG-2 cells (IC50 = 4.2 μg/mL). In order to isolated the active compounds quickly, the strategy of HPLC-ESI-Q-TOF-MS/MS combined with high-speed counter-current chromatography (HSCCC) was implemented. Three sesquiterpene lactone compounds, 2α,5α-dihydroxy-11αH-eudesma-4(15)-en-12,8β-olide (1), telekin (2), oxoeudesm-11(13)-eno-12,8α-lactone (3) were obtained. Their structures were elucidated by detailed analysis of 1D, 2D NMR and HRMS data. In addition, compounds 1-3 were evaluated for their cytotoxic activities against HepG-2 cell line with IC50 value of 9.83, 2.95, and 4.15 μM, respectively. Moreover, all compounds not only can reduce the expression of JAK2 and STAT3 mRNA but also inhibit the p-JAK2 and p-STAT3 protein expression levels in a dose‐dependent manner in the HepG-2 cells. In conclusion, three sesquiterpene lactone compounds inhibited the proliferation of HepG-2 cells via suppressing the JAK2/STAT3 signaling pathway.
Endomycorrhizal Fungal Survival in Continuous Corn, Soybean, and Fallow
Authors: Troeh Zahra I. , Loynachan Thomas E.
Published: October 2021

Survival of arbuscular mycorrhizal (AM) fungi in soil may be affected by the presence or absence of crops and by the crop being grown. Field studies were conducted in central Iowa during three growing seasons with cropping to continuous corn (Zea mays L.) (two cultivars), continuous soybean [Glycine max (L.) Merr.] (two cultivars), or fallow in three soils to determine AM selection and survival. The initial numbers of spores (all following soybean) in May 1996 averaged 0.9 g−1 soil in Clarion (well drained), 1.1 in Nicollet (somewhat poorly drained), and 3.6 in Webster (poorly drained) soils. In May 1998, the highest spore count average was 11.2 g−1 soil in Webster under corn and 3.0 spores g−1 under soybean. Nicollet soil averaged 6.8 spores g−1 for corn and 0.9 for soybean in May 1998, whereas Clarion soil had 6.3 for corn and 2.0 for soybean. The fallow treatments consistently had low spore counts, ranging from 0.7 to 1.0 spores g−1 for all three soils. After 3 yr under the same cropping regime, spore numbers in soil were corn > soybean > fallow; no significant differences were found between cultivars of the same crop. Most probable number counts were correlated with spore counts and averaged 11% of spore counts, suggesting that only a portion of the spores were viable (or culturable in our determination). By the end of the study, Glomus albidum and G. etunicatum dominated under corn, whereas G. constrictum dominated under soybean.
Improving Physiological Assumptions Of Simulation Models By Using Gene‐Based Approaches
Authors: Hoogenboom Gerrit , White Jeffrey W.
Published: October 2021

Application of crop models to plant breeding has been limited, in part due to the restricted capabilities of models to accurately represent genetic differences and genotype‐induced crop responses. A gene‐based model, GeneGro, was developed to simulate the effects of seven genes on growth and developmental processes in common bean (Phaseolus vulgaris L.) and was published in 1996. The objective of this paper is to describe the improvements that were made in GeneGro to incorporate the effect of the Tip gene. Presence of the Tip gene in photoperiod‐sensitive cultivars reduces the inhibitory effect of low temperature on photoperiod sensitivity of flowering. A mechanistic approach, further guided by information on two other genes affecting photoperiod response, i.e., Ppd and Hr, was used to incorporate the effect of the Tip gene. In the modified GeneGro, this inhibitory effect is reduced under cooler temperatures ranging from 15 to 20°C for the mean daily temperature. However, in the presence of Tip, no such reduction occurs. For the calibration data, GeneGro explained 75% of the variation in days to flower vs. 61% for the original model. For an extensive evaluation data set, the modification explained 72% of the variation in days to flower vs. 70% for the original version while days to maturity, seed yield, canopy dry mass, and harvest index showed no improvement. These results reflect two major constraints to effective use of gene‐based approaches in crop modeling. The first is the lack of reliable characterizations of cultivars for genes used in the model. The second is the scarcity of data from conditions where phenotypic differences between the Tip and tip gene would be expected. It can be concluded that understanding the genetic control of quantitative traits can guide improvements to simulation models.
Émergence des « learning analytics » en éducation : quelques défis et enjeux de l’analyse de l’apprentissage
Authors: Parent Séverine , Baron Monique
Published: October 2021

Lors du colloque EDUsummIT 2019, un groupe de travail a mené une réflexion sur l’analyse de l’apprentissage. En tant que membres francophones de ce groupe, nous présentons et discutons dans cet article les recommandations du groupe de travail quant au déploiement de l’analyse de l’apprentissage dans les établissements d’enseignement dans un avenir rapproché. Certains éléments à considérer dans l’intégration de l’analyse de l’apprentissage, dont le rôle des fournisseurs de service, les compétences nécessaires pour interpréter les données et les effets potentiels de telles analyses sur la conception de l’apprentissage, sont abordés.
Approches et paradigmes pour la recherche sur les usages éducatifs des technologies: Enjeux et perspectives
Authors: Baron Georges-Louis , Cédric Fluckiger
Published: October 2021

Les lignes qui suivent présentent une réflexion commencée à l’EDUsummIT de 2019 à Québec, notamment dans un groupe de travail sur les paradigmes de recherche souhaitables dans le domaine de l’étude des usages éducatifs des technologies de l’information et de la communication. Il déconstruit la notion de passage à l’échelle des innovations et interroge la tension entre différents paradigmes de recherche, critique les points de vue peu problématisés de certains décideurs qui promeuvent un type particulier de recherche se concentrant uniquement sur le passage à l’échelle uniquement en termes de résultats. Finalement, il argumente pour l’intérêt d’approches participatives plurielles associant des collectifs hybrides durables.
Carbamazepine removal from aqueous solution by synthesized reduced graphene oxide-nano zero valent iron (Fe0-rGO) composite: theory, process optimization, and coexisting drugs effects
Authors: Zamani Leila , Sadjadi Sodeh , Ashouri Fatemeh , Jahangiri-rad Mahsa
Published: October 2021

Synthesized Fe0-rGO nanocomposite with ratio of 1/1 (w/w) was prepared and has been used as adsorbent for the removal of Carbamazepine (CBZ) from aqueous solution. The adsorbent was characterized by various techniques such as Fourier-transform infrared spectroscopy (FTIR), energy-dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), and Field Emission Scanning Electron Microscopy (FE-SEM) analyses. Linear experiments were performed to compare the best fitting isotherms and kinetics. The Freundlich isotherm (R2>0.90) and pseudo second order kinetic (R2>0.99) fitted well the experimental data. On the basis of the Langmuir isotherm, the maximum adsorption capacity of Fe0-rGO for CBZ was up to 50 mg g−1 at 30 °C. The pH, adsorbent dose, and initial concentration of CBZ were observed to be the leading parameters that affected the removal of CBZ considering the analysis of variance (ANOVA; p<0.05). The optimum process value of variables obtained by numerical optimization corresponds to pH 3.07, an adsorbent dose of 36.2 mg, an initial CBZ concentration of 5 mg L–1 and at 30.15 °C. The results of optimum conditions reveal that a maximum of 94% removal efficiency can be achieved; whereas, this phenomenon was independent of temperature (p-value>0.05). Moreover, Fe0-rGO can be used to remove diclofenac (DIC) and cetirizine (CTZ) simultaneously. To sum up, the Fe0-rGO is a promising adsorbent not only for the efficient removal of CBZ but also for the reduction of coexisting drugs in aqueous solution.
Dental disorders in patients recovered from malignant neoplasms in childhood
Authors: Smirnov D. F. , Sidorenko L. V.
Published: October 2021

During the development of the bodyʼs homeostatic systems, anticancer drugs and radiation affect both tumor cells and healthy tissues. Damage to tissues with low potential for restorative functions, such as teeth, leads to a high probability of irreversible changes. The purpose of this literature review is to provide information on dental defects resulting from anticancer treatment. The most common anomalies in the development of teeth include a violation of the number, size, shape, mineralization of teeth, defects of dentin and enamel. The effect of a number of chemotherapeutic drugs has been studied in animal models and include a deficiency and thinning of the roots of the teeth. Irradiation leads to a wider spectrum of dental pathology: the integritation of the teeth changes, craniofacial dysmorphism, post-radiation mandibular hypomobility, damage to the salivary glands, the risk of developing osteoradionecrosis. The extent and severity of these effects depends from the child's age type of tumor and the radiation dose. The stage of tooth development is critical. Patients who received hematopoietic stem cell transplantation (HSCT) before the age of 3 have a higher risk of dental disorders and anomalies in the development and growth of the face. Radiation therapy plays a leading role in the formation of caries. The study of the long-term effects of radiation therapy, chemotherapy, HSCT on the development of dental complications is of interest to identify the most vulnerable groups of patients in order to ensure the possibility of early intervention and improve the quality of life.
Relation Between URIC Acid Levels and Subclinical Hypothyroidism in
Diabetic Patients
Authors: Shabana Hosameldeen S. , Allam Mahmoud A. , Nassar Youssef A. , Awad Amgad , Naguib Magdy M. , Elgendy Abdelaleem A. , Elmahdi Essam
Published: October 2021

Background and Aim:

Subclinical hypothyroidism (SCH) is frequently seen in diabetic
patients. Elevated levels of uric acid (UA) were also reported in diabetic patients. No study assessed
the relation between SCH and UA levels in diabetic patients. We aimed to evaluate this relation
and the association of both conditions with other clinical and laboratory parameters in diabetic
patients.

Subjects and Methods:

This cross-sectional study included 100 T2DM patients in addition to 50
age and sex matched healthy controls. Diabetic patients comprised 50 patients with SCH and 50 euthyroid
patients. All participants were subjected to careful history taking, thorough clinical examination
and standard laboratory work up. The performed investigations included fasting and postprandial
blood sugar, fasting insulin levels, HbA1c levels, thyroid hormones (FT3, FT4 and TSH),
renal profile and serum UA.

Results:

Comparison between the studied groups regarding serum UA levels revealed significantly
higher levels in the diabetic group (5.4 ± 1.9 versus 4.2 ± 1.0 mg/dl, p<0.001). SCH + DM patients
had significantly higher UA levels in comparison to DM group (6.1 ± 1.8 versus 4.8 ± 1.7 mg/dl,
p<0.001) and control group (6.1 ± 1.8 versus 4.2 ± 1.0 mg/dl, p<0.001). SCH + DM patients had
significantly higher HbA1c levels (8.9 ± 1.1 versus 7.6 ± 1.3%, p<0.001), HOMA-IR (3.9 ± 0.8 versus
2.8 ± 1.0, p<0.001) and UA levels (6.1 ± 1.8 versus 4.8 ± 1.7, p<0.001). Correlation analysis
identified a significant direct correlation between serum UA and HOMA-IR in DM + SCH patients
(r=0.4,p=0.004). In univariate analysis, presence of SCH [OR (95% CI): 2.57 (1.07-6.15),
p=0.034] and nephropathy [OR (95% CI): 4.57 (1.77-11.8), p=0.002] was significant predictors of
higher (upper tertile) UA in the studied patients. However, in multivariate analysis, only nephropathy
[OR (95% CI): 4.25 (1.62-11.17), p=0.003] continued to be significant while SCH showed a
marginal trend [OR (95% CI): 0.43 (0.17-1.08), p=0.073].

Conclusions:

The present study suggests an association between SCH and increased UA levels in
diabetic patients.
Needs Analysis Blended Laboratory in The Context of the Adequacy of Supporting Facilities for Science Learning Using the Internet of Things and Augmented Reality
Authors: Rosana Dadan
Published: October 2021

The blended laboratory model in this study refers to an integrated laboratory concept combining synchronous (real laboratory activities) using the Internet of things (IoT) and asynchronous learning with augmented reality (AR). The application of blended laboratory model in science learning teachers is still low in Indonesia due to the lack of ICT support for online learning. This preliminary study was conducted to analyze the need for the development of the blended laboratory model with IoT and AR involving 45 science teachers and 42 junior high school students as the respondents with stratified random sampling technique. The research method employed survey and focus group discussion. The results of the study showed that (1) 67% of teachers and 92% of students have never used AR, (2) 72% of teachers and 89% of students have never utilized IoT, (3) 65% of science laboratories in the junior high school do not have proper devices for AR application, (5) 76% of science laboratories in the junior high schools are not facilitated with proper equipment for the IoT application, (6) the respondents stated that the development of blended laboratory is very important (72%) and important (18%) to support IT-based learning, especially to deal with the conditions after the Covid-19 outbreak.  ©2021  JSER. Universitas Negeri Yogyakarta
Abstracts from the 2021 AMSA Reciprocal Meat Conference
Authors:   American Meat Science Association
Published: October 2021

Abstracts from the 2021 AMSA Reciprocal Meat Conference
Сравнительный анализ пороговой чувствительности ИК-систем в различных спектральных диапазонах
Authors: Знаменский И.В. , Зотьев Е.О. , Юдин С.Ю.
Published: October 2021

Представлен результат расчета пороговой освещенности оптико-­электронной системы (ОЭС) в различных ИК-поддиапазонах в интервале длин волн 0,9–5,3 мкм. Разработана методика и выполнен расчет освещенности входного зрачка ОЭС от сигнала объекта контроля (ОК) цилиндрической формы, подсвеченного Солнцем, и за счет собственного излучения обшивки ОК. Разработана программа для энергетического расчета и представлен ее интерфейс.
A Survey on the Clinical Practice Patterns of Irritable Bowel Syndrome in Korean Medicine
Authors: Jun Hyejin , Kim Keumji , Ko Seok-Jae , Park Jae-Woo
Published: October 2021

Objective: This study investigated the perception, diagnosis, and treatment of irritable bowel syndrome (IBS) in the general population, in patients, and in Korean medicine doctors (KMDs) in order to provide basic information for the development of Korean medicine clinical practice guidelines for IBS.Methods: A questionnaire was developed in two versions, one for the general population/patients and one for KMDs. The questions were about the general perception, diagnosis, and treatment of IBS. Both online and offline surveys were conducted using these questionnaires.Results: In total, 213 general population/patients and 435 KMDs responded to the survey. The results of the analysis were as follows. Most of the KMDs diagnosed IBS based on clinical aspects. Acupuncture was the most common treatment, followed by prescription herbal medicine, moxibustion, and manufactured herbal medicine. 34.3% of KMDs used clinical practice guidelines for IBS patient treatment. 57.8% of patients were diagnosed with IBS by doctors at primary medical institutions, and 53.1% were diagnosed with colonoscopy. More than half of the IBS patients who have been treated with Korean medicine said they experienced improvement of symptoms and prevention of recurrence, but more than 70% of the respondents said future safety and effectiveness studies of Korean medicine were needed.Conclusions: In spite of the positive perception of IBS treatment with Korean medicine, actual utilization was relatively low. The development and promotion of, as well as education about, appropriate and reasonable Korean medicine practice guidelines for IBS is necessary.
A Case Report of Add-On Traditional Korean Medical Treatments in a Patient with Uncontrolled Type 2 Diabetes Mellitus with Conventional Oral Hypoglycemic Agents
Authors: Lee Hye-Yoon , Jung Eun-sun , Yun Youngju , Lee Sang Yeoup
Published: October 2021

This study presents a case of add-on traditional Korean medical treatments in a 77-year-old male patient with uncontrolled type 2 diabetes mellitus with conventional oral hypoglycemic agents. Chief complaints were uncontrolled glucose level and weight loss. The patient was treated with electroacupuncture (on ST36, CV4, and CV12), herbal medication, and lifestyle advice. The conventional oral hypoglycemic medications were maintained. After 12 weeks, the glycated hemoglobin A1c (HbA1c) decreased from 11.0% to 8.4%. There were significant abnormalities in the liver function and renal function tests, but no adverse event was reported. Further studies are needed to confirm the findings of this case.
White-rot fungi-mediated bioremediation as a sustainable method for xenobiotic degradation
Authors: Kathiravan A. , Joel Gnanadoss J.
Published: October 2021

Xenobiotics are hazardous compounds that are foreign to natural ecosystems. The production and use of xenobiotic compounds continue to increase worldwide, which in turn causes environmental pollution and has adverse effects on humans. Degradation of such compounds, therefore, needs urgent awareness and attention. The physicochemical approaches to treat the contaminants are expensive. Bioremediation is a concept that exploits organisms to manage the environment with less manpower and time. White-rot fungi-mediated bioremediation offers inexpensive, environmentally sustainable and potential degradation mechanisms for different recalcitrant chemicals. White-rot fungi secrete lignolytic enzymes that have extensive substrate specificities and are involved in the transformation and solubilization of lignin-like structural contaminants. The main lignolytic enzymes occurring in white-rot fungi are laccases, lignin peroxidase, manganese peroxidase, and other peroxidases. Such lignolytic enzymes permit white-rot fungi to endure high toxic levels. This review describes the opportunities to use white-rot fungi and their enzyme systems in the biodegradation of multiple xenobiotic contaminants.
Synergistic effect of cytokinins on in vitro propagation of Stereospermum suaveolens using nodal explants
Authors: Trivedi Darshini R. , Joshi Aruna G.
Published: October 2021

The Stereospermum suaveolens DC. is one of the important medicinal tree species and also one of the important constituents of Dashmoolarisht. Owing to its importance an attempt was made to perform in vitro regeneration from nodal explants. Cultures were established by placing the nodal explants on Murashige and Skoog’s (MS) and Woody Plant media fortified with different combinations of cytokinins. The in vitro shoots developed were excised into single in vitro nodes and then utilised for multiplication of shoots. Among the various combinations tested in both of the media, the MS medium fortified with benzylaminopurine (8 µM) + thidiazuron (0.2 µM) proved to be effective in inducing a maximum of 10.2 number of shoots by the end of the fifth subculture. In vitro rooting of shoots was best achieved in ½ MS liquid medium fortified with indolebutyric acid (2.5 µM), with the highest number of roots (9.3) in 100% cultures. Well rooted in vitro plantlets were successfully hardened under greenhouse conditions, resulting in 100% survival of plants after four weeks of transfer to cocopeat/soil substrate.
Study on diversity of cladocerans (Cladocera: Branchiopoda) in some selected wetlands of West Midnapore district, West Bengal, India
Authors: Chakraborty Souraditya , Halder Mallick Priyanka
Published: October 2021

Cladocerans, also referred to as “water fleas”, are a special group of crustacean zooplankton, noteworthy for their highly nutritive value as “natural live feed” in aquaculture practices and also for maintaining ecosystem stability. Geographically, in eastern India, the district West Midnapore in West Bengal is a part of unique red lateritic soil region known as the “Rarh belt” or “Rarh Bengal”. Due to this characteristic edaphic and topographical feature the biodiversity status of the wetlands herein are of special significance. An attempt was made to record the cladoceran species diversity in three ecologically contrasting freshwater bodies (a fishpond, a village pond, and a forest pond) in Garhbeta I block, in the northern fringe of West Midnapore district, West Bengal, India. The study revealed the presence of a total of 16 cladoceran species among the three study sites. Chydoridae (56%) was found to be the dominant family followed by Moinidae (19%). The fish pond (13 species) contained the highest species diversity followed by the forest pond (10 species) and village pond (eight species) respectively. The study showed that cladoceran species diversity seemed to be positively correlated with presence of nutrients. The species diversity was associated with the eutrophication status, ecosystem stability and productivity levels of the wetlands. The maximum species diversity was found in the pre-monsoon and least in the monsoon period. Thus, increase in temperature indicated a positive correlation with species diversity. The Shannon-Weiner index (H’) value ranged between 1.81 and 2.50 among the three sites, indicating overall moderately stable ecosystems. The one-way ANOVA results indicated that the variation in H’ value across different seasons was not statistically significant, but statistically significantly differed among different sites. Similar trends were seen for species evenness index and other diversity indices as well. Bray-Curtis cluster analysis based on species distribution indicated Site I and Site III were more similar as compared to Site II. However, as the recorded species count was less than the overall species diversity (63 species) recorded in the region, further studies are recommended for greater exploration of the group in the area.
Humanización de la atención en salud: análisis del concepto
Authors: Henao-Castaño Angela Maria , Vergara-Escobar Oscar Javier , Gómez-Ramírez Olga Janeth
Published: October 2021

El análisis del concepto de Humanización de la atención en salud presenta una aproximación teórica y reflexiva de la humanización, de tal manera que se logra evidenciar los principios y los valores que otorgan un valor agregado a los servicios de salud que se prestan en un contexto cambiante.  Objetivo: Analizar el concepto de Humanización de los servicios de salud. Materiales y métodos:  Se aplicó la propuesta por Beth L Rodgers que establece siete pasos para el análisis del concepto, la investigación documental se realizó con bases de datos Springer Plus, Pubmed, EBSCO Host y Biblioteca Virtual en Salud y página de organismo nacional, en el idioma español, inglés y portugués. Resultados: Con 33 artículos científicos se logra analizar el concepto de humanización de la atención en salud y se presenta atributos éticos, epistemológicos y metodológicos, en el cual se resalta la comunicación asertiva y efectiva en la atención en salud en el contexto de la salud-enfermedad, aportando para enfermería concepciones de la humanización en el marco de la atención de enfermería. Conclusiones: La humanización de la atención en salud permite desarrollar estrategias en beneficio del bienestar y la buena práctica.  Aunque el concepto de humanización de la atención se puede analizar desde diferentes perspectivas, la metodología de análisis de concepto es una perspectiva útil para considerar a la humanización de la atención en salud como un eje orientador de políticas de mejoramiento y calidad de la atención, así como en la promoción de prácticas que facilitan el trabajo colaborativo, la comunicación y el desarrollo humano.
Cuidar a personas con cáncer: vivencias desde el afrontamiento en enfermeros
Authors: Giraldo-Montoya Dora Isabel , Mesa-Marin Andrea
Published: October 2021

Objetivo: Describir cómo viven y afrontan los profesionales de enfermería la experiencia de cuidar personas con cáncer. Materiales y métodos: cualitativo fenomenológico. El tamaño de la muestra se definió por la saturación teórica, conformada por seis profesionales de enfermería que laboraban en oncología. El instrumento fue la entrevista a profundidad. Se mantuvo la reflexibilidad, también la credibilidad a través de una segunda entrevista para corroborar los datos interpretados, notas de campo y relectura con investigadores asesores.  Para el análisis de la información se utilizó el método de Taylor y Bogdan, se plasmaron en matrices de análisis y gráficos. Fue avalado por el Comité de Ética y se utilizó el consentimiento informado. Resultados: se develaron dos temas centrales, el primero fue titulado “Que tengo que vivir, que tengo que hacer, con quien debo compartir” mecanismos de afrontamiento desde el interior y el segundo “Hay otras formas para descargarnos” mecanismos de afrontamiento desde afuera. Adicionalmente se generaron los siguientes subtemas: transformar el concepto de muerte, tener características especiales, cambiar la forma de ver la vida, ser espiritual, la seguridad que ofrece el conocimiento científico, la seguridad que ofrece la experiencia laboral, el apoyo institucional para el bienestar del trabajador y la formación universitaria en el cuidado oncológico. Conclusiones: la experiencia de cuidar a pacientes con cáncer develó mecanismos de afrontamiento que le permiten al enfermero adaptarse y resolver diversas situaciones en su quehacer profesional en los servicios de oncología
Robot-assisted resection of rectal duplication cysts: A case report
Authors: Kitazono Masaki , Fujita Makoto , Oyama Tomohiro , Ikeda Naotaka , Eguchi Mayumi , Kamimura Go , Sato Rikiya , Uchiyama Shuichiro , Toyosaki Ryoichi , Suenaga Toyokuni , Shimaoka Shunji
Published: October 2021

Rectal duplication cysts are extremely rare and account for only 4% of
all gastrointestinal duplication cysts. They may become difficult for
removal in the case of a large tumor in a narrow pelvis. Herein, we
report a case of rectal duplication cysts excision via robotic-assisted
laparoscopic surgery and its utility.
Smart dressings for wound monitoring and treatment: new-type skin bioelectronic systems applicated in wound repair
Authors: Zhong Yu-Fan , Wang Yong , Hu Yan-Yan , Wang Xiao-Feng , Xu Fa-Wei , Liu Yan-Qi , Fang Qing-Qing , Zhao Wan-Yi , Kuo Ting-Wen , Xue Ya-Nan , Tan Wei-Qiang
Published: October 2021

Wound management, especially for chronic wounds, has emerged as a major
healthcare challenge, which brings great pain and other negative impacts
to patients, and accounts for significant portions of health care
budgets. The common practice of covering wounds with dressings, owing to
the lack of information about wound healing underneath, cannot provide
insights into the status of the wound. Changing the dressings to inspect
wounds not only disturbs normal healing process of wounds, but also
causes pain to affected individuals. Therefore, it is necessary to rely
on parameters in the wound microenvironment such as temperature, pH,
moisture level, and etc., by continuously monitoring, to indicate the
wound status and healing stages. Moreover, intelligent on-demand
treatment systems also can be integrated into the smart dressing, called
new-type skin bioelectronic systems to be applicated in wound repair.
Besides monitoring, these kinds of skin bioelectronic systems can offer
effective treatments automatedly when the wound deteriorates. It makes
timely treatment possible and avoids delayed treatment and uncovering
the dressing to give medicine. In this review, wound healing-related
indexes in the wound microenvironment are discussed, applications of
various smart dressings with functions of monitoring or/and treatment
are summarized.
Drug resistance in recurrent and metastatic Ewing sarcoma
Authors: Zhang Lili , Yu Yonghua
Published: October 2021

Survival of patients with recurrent and metastatic Ewing sarcoma (ES)
has not markedly improved in the last 40 years; the main reason for the
poor prognosis of these patients is drug resistance. However, intrinsic
and acquired resistance may occur in response to both traditional
chemotherapy and targeted drugs. These complex mechanisms plausibly
include instability of the genetic material, enhanced drug efflux and
metabolism, positive DNA repair, inhibition of tumor cell apoptosis,
miRNAs, the tumor microenvironment, cancer stem cells, autophagy, and
the activation of cell proliferation pathways. The development and
application of nanoparticles bring new hope for reversing drug
resistance in ES, accompanied with encouraging results from preclinical
trials. In this review, we elucidate the molecular mechanisms underlying
drug resistance in ES and propose putative strategies to overcome this
resistance to improve prognosis of patients with ES.
The pseudo core inverses of differences and products of projections in rings with involution
Authors: Chen Xiaofeng , Chen Jianlong , Zhou Yukun
Published: October 2021

Let R be a unital ring with involution. The pseudo core inverses of
differences and products of two projections are investigated in R. Some
equivalent conditions are obtained. As applications, the pseudo core
invertibility of the commutator pq - qp and the anti-commutator pq + qp are
characterized, where p; q are projections in R.
Study of Γ-simulation functions, ZΓ-contractions and revisiting the L-contractions
Authors: Karapınar E. , Joonaghany Heidary , Khojasteh F. , Radenovic S.
Published: October 2021

In this paper, we introduce the notions of Z?-ontractions and Suzuki Z?-contractions via ?-simulation functions. By using these new
contractions, we extend and unify several existing fixed point results in
the corresponding literature. We also show that the recently defined notion
of L-simulation function is an special case of Z?-contraction. In
addition, some notable examples are given to illustrate and support the
obtained results.
Multiple interpolation in the Privalov classes in a disk
Authors: Rodikova Eugenia Gennad’evna
Published: October 2021

For all 0 < q < +? the Privalov class ?q consists of all analytic functions f
in a unit disk such that sup 0?r<1 1/2? ??,-? (ln+ |f(rei?)|)q d?<
+?. In this paper we solve a multiple interpolation problem in the class ?q
for all 0 < q < 1. Namely, we find the sufficient conditions for the explicit
construction of the function that solves the interpolation problem in the
Privalov class. In addition, we discuss the necessity of these conditions.
Prognostic Models for Predicting Remission of Diabetes Following Bariatric Surgery: A Systematic Review and Meta-analysis
Authors: Singh Pushpa , Adderley Nicola J. , Hazlehurst Jonathan , Price Malcolm , Tahrani Abd A. , Nirantharakumar Krishnarajah , Bellary Srikanth
Published: October 2021

BACKGROUND

Remission of type 2 diabetes following bariatric surgery is well established, but identifying patients who will go into remission is challenging.

PURPOSE

To perform a systematic review of currently available diabetes remission prediction models, compare their performance, and evaluate their applicability in clinical settings.

DATA SOURCES

A comprehensive systematic literature search of MEDLINE, MEDLINE In-Process & Other Non-Indexed Citations, Embase, and Cochrane Central Register of Controlled Trials (CENTRAL) was undertaken. The search was restricted to studies published in the last 15 years and in the English language.

STUDY SELECTION

All studies developing or validating a prediction model for diabetes remission in adults after bariatric surgery were included.

DATA EXTRACTION

The search identified 4,165 references, of which 38 were included for data extraction. We identified 16 model development and 22 validation studies.

DATA SYNTHESIS

Of the 16 model development studies, 11 developed scoring systems and 5 proposed logistic regression models. In model development studies, 10 models showed excellent discrimination with area under the receiver operating characteristic curve ≥0.800. Two of these prediction models, ABCD and DiaRem, were widely externally validated in different populations, in a variety of bariatric procedures, and for both short- and long-term diabetes remission. Newer prediction models showed excellent discrimination in test studies, but external validation was limited.

LIMITATIONS

While the key messages were consistent, a large proportion of the studies were conducted in small cohorts of patients with short duration of follow-up.

CONCLUSIONS

Among the prediction models identified, the ABCD and DiaRem models were the most widely validated and showed acceptable to excellent discrimination. More studies validating newer models and focusing on long-term diabetes remission are needed.
Adult-Onset Type 1 Diabetes: Current Understanding and Challenges
Authors: Leslie R. David , Evans-Molina Carmella , Freund-Brown Jacquelyn , Buzzetti Raffaella , Dabelea Dana , Gillespie Kathleen M. , Goland Robin , Jones Angus G. , Kacher Mark , Phillips Lawrence S. , Rolandsson Olov , Wardian Jana L. , Dunne Jessica L.
Published: October 2021

Recent epidemiological data have shown that more than half of all new cases of type 1 diabetes occur in adults. Key genetic, immune, and metabolic differences exist between adult- and childhood-onset type 1 diabetes, many of which are not well understood. A substantial risk of misclassification of diabetes type can result. Notably, some adults with type 1 diabetes may not require insulin at diagnosis, their clinical disease can masquerade as type 2 diabetes, and the consequent misclassification may result in inappropriate treatment. In response to this important issue, JDRF convened a workshop of international experts in November 2019. Here, we summarize the current understanding and unanswered questions in the field based on those discussions, highlighting epidemiology and immunogenetic and metabolic characteristics of adult-onset type 1 diabetes as well as disease-associated comorbidities and psychosocial challenges. In adult-onset, as compared with childhood-onset, type 1 diabetes, HLA-associated risk is lower, with more protective genotypes and lower genetic risk scores; multiple diabetes-associated autoantibodies are decreased, though GADA remains dominant. Before diagnosis, those with autoantibodies progress more slowly, and at diagnosis, serum C-peptide is higher in adults than children, with ketoacidosis being less frequent. Tools to distinguish types of diabetes are discussed, including body phenotype, clinical course, family history, autoantibodies, comorbidities, and C-peptide. By providing this perspective, we aim to improve the management of adults presenting with type 1 diabetes.
Ponowne spojrzenie na wyniki badań grodu książęcego w Błoniu
Authors: Błoński Mariusz
Published: October 2021

W artykule przytoczono najważniejsze rezultaty wykopalisk prowadzonych na grodzisku w Błoniu zwanym Łysa Góra w latach 1949–1951 i w 1971 r., zbudowanym przez Konrada Mazowieckiego w latach trzydziestych lub czterdziestych XIII w. Przedstawiono hipotezy formułowane odnośnie do odkrytych tam reliktów — pozostałości murowanego budynku uznanego za siedzibę księcia mazowieckiego, Siemowita I. Śladami budowli były m.in. cegły zdobione nacięciami i szkliwione oraz fragment powleczony farbą. W tekście zaprezentowano niepublikowane informacje o odkrytej tam ceramice budowlanej, m.in. archiwalne zdjęcia cegieł, dokładne wymiary całych egzemplarzy oraz skład chemiczny szkliwa pokrywającego ozdobne cegły. Dokonano też weryfikacji funkcji jednego z fragmentów.
Zastosowanie metod analizy modularnej i cosine quantogram w analizie sposobu rozmierzenia siedlisk regularnych wsi z nawsiem (typu Angerdorf)
Authors: Legut-Pintal Maria , Kubicka-Sowińska Anna
Published: October 2021

W artykule starano się wykazać, że zastosowanie metody cosine quantogram może wspomóc oparte na analizie modularnej studia nad układami przestrzennymi osad. Metoda cosine quantogram była dotychczas używana do określania podstawowych jednostek miar w architekturze. W badaniach struktur osadniczych może służyć jako statystyczne potwierdzenie wykorzystania modułu w rozmierzeniu i być pomocna w wyznaczeniu pierwotnej szerokości parcel. Weryfikację przeprowadzono na przykładzie regularnych wsilokacyjnych o średniowiecznej metryce (typu Angerdorf), obecnie istniejących: Mnichowice, Templewo, Czeska Wieś oraz dwóch wsi zanikłych w średniowieczu: Goschwitz na Śląsku i Hol koło Pragi. Zaproponowana metodologia może mieć szersze zastosowanie w badaniach historyczno-urbanistycznych.
Representaciones sociales de los estudiantes sobre la evaluación de los aprendizajes en ciencias sociales una noción a la diversificación de los procesos evaluativos
Authors: Valencia Bedoya Juan Felipe , Guerra Aguilar Andrés , Castaño Bolívar Walter Raúl , Vargas Cortés Alan David
Published: October 2021

La investigación se focaliza en el estudio de las representaciones sociales de los estudiantes sobre la evaluación de los aprendizajes en Ciencias Sociales del Colegio Universidad Pontificia Bolivariana y Jorge Eliécer Gaitán. Se hace necesario conocer y comprender al estudiante como un agente activo y fundamental dentro del proceso de enseñanza-aprendizaje. La investigación se sustenta bajo el paradigma interpretativo y se desarrolla bajo el método de estudio de casos múltiples. Se analizan los resultados mediante una matriz de análisis. De acuerdo con la investigación se pueden concluir tres elementos: 1. La evaluación como un acto necesario para el proceso formativo de los estudiantes; 2. La evaluación como acto de coerción; 3. La evaluación como elemento de promoción escolar. Con estos hallazgos se propone el uso de distintas estrategias con la finalidad de abordar la evaluación de los aprendizajes en Ciencias Sociales.
Responsabilidad social en las instituciones de enseñanza universitaria de criminología
Authors: Hikal Carreón Wael Sarwat
Published: October 2021

La investigación y la educación son partes fundamentales en todas las sociedades para el mejoramiento de las condiciones de bienestar, reconstrucción del caos social y de las circunstancias que así lo demanden; así como para el desarrollo profesional de sus egresados desde enfoques económicos, de identidad, satisfacción, entre otros. Para dar lugar a estos objetivos, los centros escolares en criminología tienen la responsabilidad de formar personas con alto sentido humanista, compromiso social, ético, con conocimientos necesarios para atender las demandas sociales y laborales, lo que les permitirá en el ejercicio de su función atender dos situaciones mencionadas: El impacto social y el desarrollo personal como profesional.
POLÍTICA EN LA CIVILIZACIÓN CAPITALISTA
Authors: PERTUZ MARTINEZ AYLIN PATRICIA
Published: October 2021

El siglo XX es un período de grandes cambios en lo político, económico, social, tecnológico y ambiental. En los campos político, económico y social, el siglo apropia las ideas de importantes pensadores, inclusive desde mediados del siglo XIX, que analizan las transformaciones y los problemas de una sociedad que evoluciona sin cesar. El objetivo de esta revisión teórica es analizar el desarrollo del pensamiento político de los autores clásicos y contemporáneos de la teoría social, y, en ella, el fenómeno de la globalización en el mundo capitalista. El estudio concluye que en el campo político existen diversas concepciones desde la teoría social clásica y contemporánea, como la extinción del Estado, la división de poderes, el Estado como relación de dominación, el análisis del campo político como exclusión, la propuesta  de la tercera vía. La sociedad avanza en la globalidad, pero también existen fuerzas que intentan hacer frente a  la globalización.
CFD analysis of thermal comfort in hospital operation room with different air distribution design and operative temperature
Authors: Husain Hazran , Mohd Samidi Muhamad Zharif , Meon Mohd Suhairil
Published: October 2021

The operation room is one of the most critical regions in hospital that require extra attention in air ventilation and prevention of dangerous pollutants contamination. A good level of ventilation will help to raise the productivity of workers in terms of performance and ensuring a safe surgery operation. It is obvious that today's operation rooms are completely equipped with mechanical ventilation systems. However, despite the fact that they meet the acceptable comfort standards, surgical workers have complained about thermal discomfort during operation which gives negative impact on their performance. Thermal comfort can be achieved by controlling the temperature, relative humidity and air movement. In this study, the operation room models are simulated to analyze the comfort conditions of surgical workers under 3 different air velocities at 0.2 ms-1, 0.25 ms-1 and 0.35 ms-1 and under 5 different temperatures between 16℃ to 20℃. Additionally, there are two 3D models created with different position of exhaust vent. The thermal comfort of surgical workers is measured using Predicted Mean Vote (PMV) and Predicted Percentage Dissatisfied (PPD) approaches using CBE Thermal Comfort Tool. The PMV and PPD results show that most surgical workers were outside the acceptable range value of -0.5 to +0.5 stated in ASHRAE Standard 55-2020. According to thermal scale index, most of the surgical workers were in a cool and slightly cool state despite the fact that the computational analysis shown an acceptable simulation validated with previous research studies. Finally, it has been discovered that clothing insulation, metabolic rate, mechanical equipment and air distribution design play a significant influence in providing comfort to the surgical workers.