bluuebunny/crossref_metadata_2025 huggingface dataset:
Peranan Manajemen Keuangan dalam Bank Sampah Sebagai Upaya Meningkatkan Nilai Pendapatan Bagi Masyarakat Kelurahan Cimpaeun Kota Depok Pada Masa Pandemi Covid
Authors: Sudaryanto Sudaryanto , Sariningsih Nining , Indrawan Bambang , Putri Dita TriAriyani , Asyifa Nita Laila
Published: November 2022

Tujuan dari kegiatan ini adalah untuk meningkatkan kesadaran akan peran pengelolaan keuangan dalam proses bank sampah. Melihat permasalahan yang muncul, langkah-langkah yang dilakukan untuk mencapai maksud dan tujuan kegiatan ini dikomunikasikan kepada dinas terkait yaitu masyarakat melalui seminar, sosialisasi dan pelatihan, menjelaskan tujuan pengelolaan keuangan dan peran penting Bank Sampah. dalam rangka penguatan sumber daya manusia melalui rangkaian identifikasi, evaluasi dan perencanaan kegiatan pendidikan. Untuk menjawab tantangan ke depan, tim akan memberikan pelatihan kepada seluruh warga dan anggota masyarakat di Cimpaeun Depok, serta inovasi-inovasi baru yang perlu dikembangkan dari sisi pengelolaan keuangan.Kata kunci : Manajemen Keuangan, Bank Sampah
A corpus-based study of reporting verbs in academic Portuguese
Authors: Matte Marine Laísa , Marchioro Stumpf Elisa
Published: November 2022

Referring to other sources is a cornerstone in academic writing and one way of framing someone else’s ideas is through reporting verbs. There is little research on this phenomenon in academic Portuguese. Most of these studies analyze reporting practices without focusing on linguistic aspects (Bessa 2011; Hoffnagel 2010), with few studies on reporting verbs (Souza and Mendes 2012). The aim of this paper is to analyze how reporting verbs are used in the Corpus of Portuguese for Academic Purposes (CoPEP; Kuhn and Ferreira 2020), a corpus of research articles in Brazilian and European Portuguese. CoPEP was divided into two subcorpora: one with texts related to Hard Science (engineering, exact-earth science, and health science), and another with texts related to Soft Science (applied social science and humanities). Sketch Engine (Kilgarriff et al. 2014) was used to extract the verbs that are used before and after the lemma autor ‘author’. Results indicate that texts in Hard Science have a slightly higher frequency of reporting verbs than texts in Soft Science, but both rely on similar reporting verbs to cite the voice of others. There is preference for the present tense in comparison with past and future, for the active voice in detriment of the passive voice, and for the order ‘author + verb’.
A logística reversa como um diferencial competitivo para empresas alimentícias
Authors: Ribeiro Manoel Azevedo , Souza Ítalo da silva Passos Lima Albano de , Reuter Júnior Rogério Daniel , Roberto José Carlos Alves , Pinto Junior José Roberto Lira
Published: November 2022

O presente estudo aborda uma ramificação da área da logística, a logística reversa, que consiste em ações voltadas para a reutilização de resíduos, reaproveitamento de qualquer descarte ou sobras da produção, descarte correto de lixo, bem como ações de conscientização ambiental dos colaboradores e consumidores. Ante ao exposto, o presente artigo, visa investigar: como a logística reversa pode ser aplicada em empresas do ramo alimentício? Sendo assim, tem-se como objetivo apresentar a logística reversa como um diferencial competitivo para as organizações que atuam com alimentos. Para isso, a metodologia utilizada foi bibliográfica, sendo realizada uma pesquisa em livros, sites e artigos científicos. Como resultados, verificou-se que, devido à crescente preocupação com a preservação do meio ambiente, a logística reversa vem sendo cada vez mais estudada, a fim de diminuir os danos significativos e irreversíveis que o descarte incorreto de lixo acarreta ao planeta. Por fim, concluiu-se que a logística reversa, quando aplicada em empresas do ramo alimentício, pode-se apresentar como um diferencial competitivo, uma vez que agrega uma boa imagem à empresa e fideliza os clientes pelo fluxo reverso, que se dá pelo fato de as empresas oferecem um suporte no pós-venda ou pós-consumo do produto.
Educação financeira: sugestão de práticas para a formação dos alunos
Authors: Mendes Geicyanne de Almeida Reis , Martins Dieny Fonseca , Silva George Felipe Gomes da , Roberto José Carlos Alves , Pinto Junior José Roberto Lira
Published: November 2022

A educação financeira tem como função principal gerar conhecimento para entender as funcionalidades do recurso monetário de forma crítica e analítica, visando obter perspectivas mais ampla da situação financeira, bem como possibilitando melhor qualidade de vida aos indivíduos. Neste contexto, o presente artigo tem como questão norteadora: como a educação financeira pode auxiliar na formação dos discentes? Desta forma, tem-se como objetivo relatar a educação financeira como uma ferramenta que auxilia na formação dos discentes e sugerir algumas práticas que podem ser utilizadas pelos docentes. Para isso, realizou-se uma pesquisa de natureza qualitativa, de método descritivo e meios bibliográficos. Como resultados, verificou-se que a educação financeira promove uma melhor qualidade de vida aos discentes, diminuindo as preocupações com dívidas através de noções do gerenciamento responsável da vida financeira. Constatou-se, também, que ela promove uma melhor compreensão, entendimento e possibilidade de lidar de forma estratégica e inteligente com os seus recursos monetários.
As ferramentas do endomarketing e o seu impacto nas organizações
Authors: Alves Emmily Alexandra Beltrão , Lobo Junior Eduardo Jorge Gomes , Alecrim Júnior Tércio Márcio Oliveira , Roberto José Carlos Alves , Pinto Junior José Roberto Lira
Published: November 2022

O endomarketing é uma ferramenta que pode ser aplicada no âmbito organizacional, a fim de auxiliar a organização a crescer e alcançar seus objetivos, promovendo ações que visam maior comprometimento dos empregados e melhorias na comunicação interna. Nesse cenário, o presente artigo, tem como questão norteadora: quais são as ferramentas do endomarketing e como elas impactam o ambiente organizacional? Sendo assim, tem-se como objetivo relatar algumas ferramentas do endomarketing e demonstrar a influência dessas para o crescimento de uma organização. Para isso, adotou-se, como metodologia, a revisão bibliográfica. Como resultados, verificou-se que o endomarketing, por meio de suas ferramentas, busca ensinar que é possível desenvolver melhores relações entre os funcionários e a empresa, motivando-os a realizar seu trabalho com maior qualidade e comprometimento. Por fim, conclui-se que o impacto do endomarketing no ambiente organizacional pode ser verificado através dos resultados positivos que a aplicação de suas ferramentas traz, motivando e aumentando o nível de produtividade dos colaboradores.
A relação do clima organizacional com a satisfação e motivação dos colaboradores
Authors: Alves Leticia Nayara Lopes , Cruz Tainara Sobreira , Silva Luana Alves da , Roberto José Carlos Alves , Pinto Junior José Roberto Lira
Published: November 2022

Acredita-se que o estudo adequado do clima organizacional pode aperfeiçoar os resultados relacionados à satisfação e motivação do colaborador, melhorando, assim, seu rendimento, de modo a trazer resultados positivos para a organização. Por essa razão, este artigo se propôs a analisar: qual é a relação entre a satisfação e motivação dos colaboradores com o clima organizacional? Dessa forma, estabeleceu-se como objetivo geral apresentar a importância de um clima organizacional saudável para a satisfação e motivação dos colaboradores, visando o crescimento da organização. Baseando-se nisto, este artigo utilizou como metodologia a pesquisa bibliográfica, de caráter exploratório e natureza qualitativa. Logo, como resultados, constatou-se que a satisfação e a motivação dos colaboradores só podem ser alcançados se a organização investir em um ambiente adequado e saudável, prezando por um bom clima organizacional. Nesse aspecto, com a ajuda dos indicadores de clima organizacional, as organizações poderão identificar a necessidade de investir na satisfação e motivação dos colaboradores, visando aumentar, assim, seus desempenhos e resultados, de modo a contribuir com o crescimento da organização.
Momento zero da verdade enquanto uma ferramenta estratégica para a sociedade empresarial
Authors: Maia Vanda Heloisa Lopes , Santos Ana Vitória Almeida dos , Batista Vitória da Mota , Roberto José Carlos Alves , Pinto Junior José Roberto Lira
Published: November 2022

Com a crescente competitividade no mercado, principalmente com a ascensão dos negócios online, é necessário que as empresas busquem entender o comportamento dos seus consumidores para, assim, adquirir vantagens competitivas. Sob essa perspectiva, este artigo levantou como questão norteadora: como o Momento Zero da Verdade pode contribuir com a sociedade empresarial, enquanto uma ferramenta estratégica? Para tanto, teve-se como objetivo geral apresentar o que é o Momento Zero da Verdade e como este pode ajudar a sociedade empresarial enquanto um diferencial competitivo. Dessa forma, realizou-se, como metodologia, uma pesquisa bibliográfica, de natureza qualitativa e de caráter exploratório e descritivo; por meio da qual, foi possível evidenciar que o ZMOT ou Momento Zero da Verdade é uma ferramenta estratégica que permite à sociedade empresarial estudar o comportamento do comprador online, promovendo informações importantes que poderão trazer vantagens competitivas para as empresas ao contribuir com a reformulação de métodos e estratégias de marketing.
Imposto sobre circulação de mercadorias e serviços: base de cálculo
Authors: Pinheiro Karina da Silva , Rissardi Ludmylla da Silva , Roberto José Carlos Alves , Anjos Carlos André Silva dos , Cavalcante Zuila Paulino
Published: November 2022

O presente artigo buscou abordar acerca do Imposto sobre a Circulação de Mercadorias e Serviços (ICMS) e sua base de cálculo. Nesse aspecto, estabeleceu-se como questão norteadora: como é realizado o cálculo do imposto sobre circulação de mercadorias e serviços? Com o objetivo geral de apresentar como é executada a base de cálculo do ICMS. Para tanto, realizou-se uma pesquisa bibliográfica, de natureza qualitativa e caráter descritivo, chegando à conclusão de que a base de cálculo do ICMS consiste na multiplicação do valor da mercadoria pelo valor da alíquota de cada local, determinada por cada estado e município.
Auditoria interna como ferramenta de controle e gestão de riscos empresariais
Authors: Moura Jessyca Bastos de Souza , Pereira Sandy Mattos , Carvalho Ícaro Vitor Vidinho de , Roberto José Carlos Alves , Cavalcante Zuila Paulino
Published: November 2022

O processo de globalização e os avanços tecnológicos vêm sendo responsáveis por transformarem o mercado em um setor cada vez mais competitivo, promovendo um cenário de riscos e incertezas para as organizações. Nesse contexto, a utilização de ferramentas como a auditoria interna, se torna importante a fim de que haja uma gestão eficiente que possibilite a identificação de riscos e a construção de conclusões fundamentais para a tomada de futuras decisões das empresas. Sendo assim, o presente artigo visa responder: como a auditoria interna pode ser utilizada para a gestão de riscos empresariais? Tendo como objetivo relatar a utilização da auditoria interna na gestão de riscos empresariais de acordo com a literatura já publicada. Para isso, realizou-se um estudo de natureza bibliográfica qualitativa, baseado na coleta de informações subjetivas. Os resultados do presente estudo asseguram que o controle e a gestão de riscos empresariais requerem planejamento e monitoramento contínuos, a fim de que a avaliação dos procedimentos seja realizada de forma eficiente, auxiliando nas futuras tomadas de decisões. Sobre este aspecto, é notável que a auditoria interna desempenha um papel crucial em uma empresa, estando diretamente associada ao seu crescimento.
A A Review on the Potential of Application of CRISPR/Cas9 Technology in CYP3A4 and CYP2D6 Genes: A Way to Move Forward in Identifying New Drug Targets
Authors: Hatta Fazleen Haslinda Mohd , Othman Ahmad Azani , Yusoff Rosmadi Mohd , Nor Azam Siti Norsyuhada , Ali Hassan Aliah Zuhairah
Published: November 2022

The cytochrome P450 (CYP) enzymes are of a ubiquitous heme–thiolate proteins family that plays an important role within the biotransformation of endogenous molecules and xenobiotics as today’s market is bio-transformed through CYP-mediated metabolism. Major CYP isoforms involved in most reactions are mainly CYP3A4 and CYP2D6. The CYP3A4 is found most extensively within the human liver and gut in which this CYP-isoform takes part in the phase I transformation of toxins, carcinogens, bile acids, and steroid hormones while CYP2D6 plays a central role in the oxidative metabolism of up to 25% of drugs in common clinical use, although it only accounts for 1-5% of the CYP liver content. With the help of vast gene editing technologies such as the CRISPR/Cas9 system, researchers have found its application to be useful and efficient in gene knockout studies involving genetic variants in association with drug metabolism due to its simplicity and affordability. Hence, this review aims to explore the potential use of CRISPR/Cas9 technology in gene editing in vitro studies particularly in knocking out the gene of interest, mainly drug metabolism enzymes. This article will explore how CRISPR/cas9 facilitates ex vivo assays of drug metabolism studies. The long-term goal for bio-editing is an in vivo treatment without the risk of causing harm to humans and providing a ready-to-be-used drug metabolism assay for ex vivo studies of drug development and pharmacokinetics study at a lower cost.
Heart transplants: Identity disruption, bodily integrity and interconnectedness
Authors: Mauthner Oliver E. , Luca Enza De , Poole Jennifer , Abbey Susan E. , Shildrick Margrit , Gewarges Mena , Ross Heather J.
Published: November 2022

Of heart transplant recipients, 30 per cent report ongoing or episodic emotional issues post-transplant, which are not attributable to medications or pathophysiological changes. To this end, our team theorized that cardiac transplantation introduces pressing new questions about how patients incorporate a transplanted heart into their sense of self and how this impacts their identity. The work of Merleau-Ponty provided the theoretical underpinning for this project as it rationalizes how corporeal changes affect one’s self and offer an innovative framework to access these complex aspects of living with a transplanted heart. We used visual methodology and recorded 25 semi-structured interviews videographically. Both visual and verbal data were analyzed at the same time in an iterative process. The most common theme was that participants expressed a disruption to their own identity and bodily integrity. Additionally, participants reported interconnectedness with the donor, even when the transplanted heart was perceived as an intruder or stranger. Finally, transplant recipients were very vivid in their descriptions and speculation of how they imagined the donor. Receiving an anonymous donor organ from a stranger often leaves the recipient with questions about who they themselves are now. Our study provides a nuanced understanding of heart transplant recipients’ embodied experiences of self and identity. Insights gained are valuable to educate transplant professionals to develop new supportive interventions both pre- and post-transplant, and to improve the process of informed consent. Ultimately, such insights could be used to enable heart transplant recipients to incorporate the graft optimally over time, easing distress and improving recovery.

 
Changes in Nicotine Metabolite Ratio among Daily Smokers receiving Treatment for Alcohol Use Disorder
Authors: Dermody Sarah , S. Hendershot Christian , Andrade Allyson K. , Novalen Maria , F. Tyndale Rachel
Published: November 2022

Introduction. Alcohol may influence the nicotine metabolite ratio (NMR), an index of the rate of nicotine metabolism that is associated smoking level and lapses. We examined if NMR changes during alcohol use disorder (AUD) treatment and how changes in NMR relate to reductions in drinking. Methods. Using an observational design, 22 daily smokers (63.64% male, Mage=46.77 (11.37)) receiving AUD treatment completed baseline and follow-up appointments three weeks apart. At each appointment, daily alcohol and cigarette use, salivary and urinary NMR, nicotine exposure via urinary total nicotine equivalents (TNE), and carbon monoxide (CO) were assessed. Multilevel models examined the change over time in NMR and its within-person relations with changes in drinks per week. Sex differences were evaluated. Results. There were significant reductions in both salivary and urinary NMR over time for men (p=.02; p=.01, respectively) but not for women (p=.54; p=.90). There were no changes over time in TNE (p=.09), CO (p=.44), or cigarette use (p=.44), in either sex. Drinks per week were significantly reduced for men (29.12 drink reduction, p<.001) but not for women (2.28 drink reduction, p=.80); however, within-person changes in drinking were not associated with changes in salivary or urinary NMR (p=.99; p=.19). Conclusions. The reduction in alcohol use and NMR in men provides indirect support for alcohol increasing NMR. In contrast, the low baseline drinking and lack of alcohol reduction likely underlies the lack of change in NMR in females. Reasons for NMR reductions during AUD treatment and its effects on smoking require further study. 
The Associations between Religion, Impulsivity, and Externalizing Behaviors in the Adolescent Brain Cognitive Development (ABCD) Study
Authors: Fahey Kalina M. L. , Nakai Saki C. , Edwards John A. , Dermody Sarah
Published: November 2022

 In studies of adolescents and adults, religiosity has been identified as a protective factor for impulsivity-related behaviors and externalizing problems. No known studies to date have examined the relationship between religiosity and such outcomes in children. Thus, the current study examined in children whether (1) religion is associated with decreased impulsivity and externalizing symptoms, and if (2) religiosity is a protective factor in the association between impulsivity and externalizing symptoms. Data were from Wave 1 of the Adolescent Brain Cognitive Development (ABCD) study (children aged 9-10, N =11,875). Two self-report measures and the Cash Choice Task assessed impulsivity; the Child Behavior Checklist assessed externalizing symptoms; and child religiosity was assessed in parent interviews. Structural equation models examined religiosity (affiliation, service attendance, importance) as a moderator between impulsivity and externalizing symptoms. Greater religious attendance was significantly associated with decreased impulsivity. Christian affiliation was associated with increased impulsivity as compared to other religions. Contrary to our hypotheses, religiosity did not moderate associations between impulsivity and externalizing symptoms. Findings suggest impulsivity and externalizing behaviors are related to some domains of religiosity in children; however, the magnitude of the effect sizes was small, suggesting religiosity is not a particularly salient predictor of externalizing problems in children. Given these findings differ from those seen in studies of adolescents and adults, future studies should consider longitudinal designs to better understand how these relationships form across the lifespan. 
Synergy of Management of Coastal Areas and Small Islands Authority Perspective
Authors: Simanjuntak Parojahan , Saraswati Retno , Setiyono Joko
Published: November 2022

This study aims to analyze the synergy in the management of coastal areas and small islands from an authority perspective. Coastal areas and small islands are areas that have enormous potential for improving people's welfare, especially coastal communities. This area, apart from having a conservation function, also has another very important function for the provision of marine goods and services. This great potential needs to be managed across sectors so that all functions can be utilized properly and sustainably. For this reason, the government issued Law no. 27 of 2007 concerning the Management of Coastal Areas and Small Islands, which was later revised by Law no. 1 of 2014 on the grounds that the Integrated Coastal Management, which is marked by the absence of renewal of unequal control and exploitation and the existence of a lack of synchronization with other laws and regulations. This law emphasizes the investment aspect and is more in favor of the business world so that there is no room for the community, especially traditional fishing communities and indigenous peoples, to propose management plans for coastal areas and small islands. With the revision, it is hoped that the rights of traditional communities, especially economic rights, are generally accommodated in the planning, utilization and monitoring process, as well as supervision related to the management of WP3K.
Analisis Persebaran Karbon Dioksida di Ruang Kampus Universitas Batanghari
Authors: S Guntar Marolop , Suhendra Suhendra
Published: November 2022

Salah satu jenis gas yang menjadi perhatian dunia saat ini adalah gas karbon dioksida (CO2) karena merupakan salah satu unsur gas rumah kaca (GRK) yang menjadi pemicu terjadinya pemanasan global dan perubahan iklim. Universitas Batanghari (Unbari) sebagai salah satu perguruan tinggi swasta di kota Jambi difungsikan sebagai ruang beraktivitas Tri Dharma Perguruan Tinggi.  Minimnya vegetasi di ruang kampus Unbari maka perlu diketahui besar dan persebaran CO2. Ruang yang minim RTH akan mempengaruhi besar dan persebaran CO2. Bila CO2 ruang kampus Unbari melebihi baku mutu maka akan berpengaruh pada kesehatan civitas akademika. Menurut Permenkes No. 1077 Tahun 2011, persebaran CO2 yang melebihi 350 ppm akan mempengaruhi tingkat kesehatan manusia. Oleh karenanya perlu dilakukan penelitian tentang besar dan sebaran konsentrasi CO2 di ruang kampus Unbari. Penelitian ini menggunakan metode  deskriptif, yaitu penelitian dengan pendekatan kuantitatif untuk menggambarkan besar dan persebaran gas CO2 dan suhu di ruang terbuka dan ruang kuliah Unbari. Teknik pengumpulan data menggunakan data primer diukur dengan alat ukur CO2 meter. Pengukuran dilakukan pada pagi, siang dan sore hari. Data primer CO2 dan suhu (T) hasil pengukuran disusun dalam bentuk tabel dan digambarkan secara grafik. Data sekunder diperoleh dari refrensi yang berhubungan dengan CO2. Hasil penelitian menunjukkan bahwa pada pagi, siang dan sore hari  di ruang terbuka terukur bahwa kadar CO2 mencapai (361-531) ppm melebihi yang dipersyaratkan oleh Permenkes No. 1077 Tahun 2011 yakni sebesar 350 ppm. Konsentrasi CO2 di ruang terbuka depan Unbari lebih tinggi yakni (385-1004) ppm. Tingginya CO2 ini dipengaruhi oleh kepadatan lalulintas jalan Slamet Riyadi di depan kampus Unbari. Konsentrasi CO2 di ruang kuliah paling tinggi 758 ppm, masih memenuhi Permenkes No. 1077 Tahun 2011.
MEMORY AND FACTORS AFFECTING MEMORY IN ORAL HISTORY STUDIES
Authors: AYDEYER Caner
Published: November 2022

Oral history constitutes one of the most important aspects of history, not as a theory but as a method. From the middle of the twentieth century, historians began to develop a range of theories about subjectivity, memory, and narratives from memories of the past. Oral history therefore plays an important role in ensuring that the wartime horrors committed against humans in the twentieth century are not forgotten. However, there are many factors that affect the narratives of oral sources while conducting oral history research in this important role. It is important for historians studying oral history to evaluate these factors very well and to compare these factors with different aspects, which affect the truthfulness of the narratives, in order to carry out an impartial study. In the study, it was emphasized what kind of issues researchers working on oral history should pay attention to. In addition, it was mentioned what should be paid attention to in order to fully comprehend the reality of the subjects told by the people interviewed and whose memories were compiled within the scope of oral history. In addition, it was tried to explain the situations that the people whose memories were consulted could be affected by the events they told. For this, the main sources written on the subject in the literature and the works of the authors who made oral history studies were used. As a result, it has been seen that at the beginning of the issues to be considered in oral history research, attention should be paid to the physical and mental states of the oral history narrator that affect his memory. This is because they cause events to be misremembered or misrepresented. Therefore, all these situations should be evaluated thoroughly and the information given by the oral history narrator should be evaluated in the light of these
Diversity of Zooplankton and Influences of Hydrobiology on Mangrove Backwaters of Ennore, Tamil Nadu, India
Authors: V. Padmavathy , Serebiah J. Sesh , C. Stella
Published: November 2022

Hydrobiology regulates the plankton diversity in a water body and is a fundamental research area in aquatic and ecological studies. The present study was carried out to assess the zooplankton diversity and physicochemical parameters viz. temperature, salinity, pH, phosphate and nitrite by collecting water samples at four stations in Ennore estuary for the period of one year from January to December 2021. Investigation of species diversity, composition, richness and evenness predicted that the diversity status of zooplanktons is influenced by the hydrobiology of Ennore backwaters.
Protection Measures for Staff Handling the Biomedical Waste - An Overview
Authors: Mukta Sharma , Anandveer Singh Sindu
Published: November 2022

Effective confinement of Biomedical waste (BMW) and safe handling measures provide significant health protection. The handling of waste entails health risks for staff throughout the chain. The protective measures reduce the risks of accident/exposure or the consequences. This review focuses on protection measures for staff handling the BMW with respect to: (1) personal protective equipment (PPE); (2) personal hygiene; (3) vaccination; (4) measures taken in accidental exposure to blood (AEB); (5) emergency measures in the event of spills/contamination of surfaces and contamination of persons; and (6) training of hospital staff.
Allometric Relationship of Freshwater Crabs Oziotelphusa bouvieri and Spirallothelphusa wuellerstorfi of Puzhal Lake, Chennai, Tamil Nadu, India
Authors: S. Vijayananth , N Thirunavukkarasu , H. Sruthi
Published: November 2022

Freshwater crabs are the most dominant and specifically endemic species in India. Ecologically and nutritionally freshwater crabs proved to be the best alternative for marine crabs. Culturing of freshwater crabs are less tedious than freshwater fishes but lack of proper research on stock assessment becomes major drawback. Stock assessment helps in evaluating actual population dynamics in order to assess its population density which would be further used for designing aquaculture practices. Simple regression proved to be effective statistical tool for calculating relative growth. Due to very fragmentary work on allometry of freshwater crab species, there is an urgent need to evaluate the actual population dynamics of freshwater crabs.
Seasonal Distribution of Nutrients in Water and Sediment of Three Coastal Region of Palk Bay Area, India
Authors: K Priyanka , Peter V. Sugumar Sarah Tamilkani
Published: November 2022

The present study was carried out to determine the seasonal distribution of nutrients in water and sediment of three coastal region of Thondi, Kottaipattinum and Sethubhavachatirum for a period of one year from January 2018 to December 2018. The analysis of different parameters such as nitrite, nitrate, ammonia, total nitrogen, inorganic phosphate, total phosphate, silicate, pH sediment, total phosphate, total nitrogen and total organic carbon were carried out using standard methods in water as well as in sediment. The nitrite values varied between 0.214 to 0.892 µm/l, 0.128 to 0.848 µm/l and 0.097 to 0.917 µm/l; nitrate values varied between 1.316 to 4.881 µm/l , 1.87 to 4.411 µm/l and 7.029 to 12.045 µm/l; ammonia values varied between 1.316 to 4.881 µm/l, 1.87 to 4.411 µm/l and 7.029 to 12.045 µm/l; total nitrogen values varied between 16.976 to 29.512 µm/l, 14.765 to 28.225 µm/l and 12.776 to 23.541 µm/l; inorganic phosphate values varied between 0.354 to 1.98 µm/l, 0.292 to 1.967 µm/l and 0.483 to 1.84 µm/l; total phosphorus values varied between 1.033 to 2.508µm/l, 0.83 to 2.816 µm/l and 1.418 to 2.953 µm/l; silicate content values varied between 25.217 to 54.074 µm/l, 30.883 to 59.872 µm/l and 28.217 to 48.074 µm/l at Thondi, Kottaipattinum and Sethubhavachatirum, respectively. In sediment, pH varied between 8.0 to 8.20, 7.9 to 8.20 and 8.0 to 8.10; total phosphorus 0.15 to 2.61, 2.31 to 3.31 and 0.91 to 2.17; Total nitrogen 6.50 to 12.95 µg/g, 4.85 to 11.96 µg/g and 5.17 to 8.08 µg/g and the total organic carbon 1.57 to 5.36, 2.21 to 3.59 and 1.48 to 4.15 at the three stations
Formulation of Nutrient Enriched Cookies from Chia (Salvia hispanica L) Seeds - A Pilot Study
Authors: V. Ramabhai , M. Jayaprakashvel , S. Chandresh , J. Shanmugapriya , Wyson John
Published: November 2022

Bakery products are most popular segments of food processing industry and can be easily enriched with nutrients and fortify to meet the nutritional requirements. Hence, this study was aimed to investigate the formulation and fortification of nutrient enriched cookies from chia (Salvia hispanica L) seeds. In this study, the cookies were prepared and standardized with 30, 20 and 10 % of Chia seeds. The nutrimental and DPPH antioxidant properties of cookies were identified using stranded methodology. The results of the present study indicated that 30% Chia seeds have high nutrient value and content of the nutrient value is 21.76g, 39.91 and 7.2 in carbohydrates, protein and lipid, respectively and free radical scavenging activity was highest inhibition activity in 30% chia seeds (52.06%) at 500 ug/ml concentration. This study indicated that the enriched cookies (30% chia seeds) have more functional components and effective antioxidant capacity. Their supplementation could provide the consumers a novel cereal based product with health promoting benefits
Large Scale Analysis Of Tick Infestation And Physiological Responses In Native And Cross Bred Cattle Populations Reared In Central Plains Of Uttar Pradesh, India
Authors: Kamal Jaiswal , Mukesh Manishi , Suman Mishra , Vivek Prince , Amit Singh , Saumya Sharma , Awanish Kumar Singh
Published: November 2022

Tick and tick-borne diseases cause major economic losses to world’s dairy sector. India, being tropical country also faces tremendous challenges from wide arrays of ticks that infest all kind of dairy animals. As we understand that any kind of stresses can disturb the physiological parameters of dairy animals that can impact the animal productivity and over-all performance. In this study therefore, an effort was made to evaluate the physiological responses of tick infested and non-infested native (Sahiwal) and cross bred cattle populations in the central plains area of Uttar Pradesh, India. A total of 3570 animals of indigenous and crossbred cattle from organized and unorganized cattle farm located in and around Lucknow, Uttar Pradesh area was surveyed across seasons (winter, hot summer and hot humid) to assess the prevalence of tick infestation and their effect on physiological responses. The present study revealed that the crossbred cattle were most susceptible to tick infestations. The prevalence of tick infestation was significantly (P<0.05) higher in humid season in both indigenous (Sahiwal) and crossbred cattle. The tick infestation rate (%) in Sahiwal cows were 5.2 and 7.52 in hot summer and humid seasons, respectively. However, in crossbred cattle, the tick infestation rate was 59 (±0.25) and 69.24 (±1.60) in hot summer and humid season, respectively. In the cattle maintained at unorganized farm, the prevalence rate (%) of tick infestation in non-descript cattle was found to be 39.27±1.57, 45.08±1.12 and 27.47±2.01, during hot summer, humid and winter season, respectively. Whereas in the crossbred cattle from unorganized cattle farms, tick infestation rate was 58.93±1.07, 69.05±4.09 and 47.78±6.71 during hot summer, humid and winter season, respectively. The physiological responses in tick-infested cattle were found to be significantly (P<0.05) different in the present study. In tick non-infested Sahiwal cattle, the RT decreased significantly (P<0.05) in winter season. Likewise, PR of tick-infested and non-infested cattle significantly (P<0.05) decreased in winter season. While the RR significantly increased in tick-infested cross bred cattle in humid season, followed by a significant (P<0.05) decrease in winter season. Furthermore, the respiration rate was significantly higher in tick-infested cross breed and nondescriptive cattle. In conclusion, the prevalence of tick infestation was higher in the crossbred cows, followed by non-descript cattle and indigenous Sahiwal cattle.
Anticancer Activity of Iron Oxide Nanoparticles Synthesized from Chitosan Aqueous Extract of Penaeus monodon Shrimp Shells Against Pc-3 Cell Line
Authors: E. Venkadachalam , V. Indra , B. Sangeetha , Pavithra Deenadayalan
Published: November 2022

Magnetic iron oxide nanoparticles (Cs-FeNPs) are increasingly being studied for potential anticancer applications to circumvent off-target cytotoxicity and other side effects from conventional chemotherapy. In this study chitosan aqueous extracts were used as natural stabilizers to synthesize Cs-FeNPs followed by a series of characterization experiments and in vitro anticancer evaluation. Morphological studies demonstrated that adding peel extract decreased the size of NPs with an average particle size below 100 nm. Cytotoxicity assay showed that the Cs-FeNPs were more reactive (IC50 29.759 µg/ml) against PC-3 cancer cell lines and normal Vero cell lines. Specifically, Cs-FeNPs displayed potent anticancer activities against PC-3 cell line. This study showed the characterization of eco-friendly synthesized Cs-FeNPs and their potential use as anticancer therapeutic agents against PC-3 cells.
Study of Ophio Fauna in and Around Indapur of Pune District, Maharashtra, India
Authors: S.T. Bhong , T.S. Pathan , S.R. Kudale
Published: November 2022

One of the most widely distributed vertebrates on the planet, snakes tend to prefer arid regions due to their diversity. The present paper deals with geographical, ecological distribution and biodiversity of snakes in the area of Indapur tehsil district Pune, India. The present investigation was undertaken to study the diversity of Ophio fauna from Indapur tehsil Pune district. In this study there was 15 species of snakes belonging to 14 genera, 5 families. In which Colubridae is most diverse snakes family from Indapur tehsil. The findings indicated that there are 15 species of snakes from 5 families present in the Indapur tehsil; Eight genera and eight species belonging to the family Colubridae, including the rat snake, water snake, grass snake, banded racer, wolf snake, Trinket, Kukri, and cat snake; two genus and two species of elapids- Common krait and Indian cobra. Viper and saw scaled viper are two species belonging tothe family Viperidae.
Breeding Behaviour of Black-Winged Stilt, Himantopus himantopus (Linnaeus, 1758) in Agricultural Landscape of Punjab, India
Authors: Sandeep Kaur Thind , Charn Kumar , Amritpal Singh Kaleka
Published: November 2022

During the breeding seasons (2017-2019), the hitherto little known aspects of breeding behavior of Black-winged Stilt, Himantopus himantopus were studied in the ploughed agricultural fields, village ponds and adjacent shallow pools located in rural outskirts in district Ludhiana, Punjab, India. Observations on nest structure, egg laying, incubation, hatching and other behavioural aspects of the parents/chicks were inferred from videorecords, photographs and direct field observations made on 19 clutches containing 59 eggs. In the study area the breeding season extended from April to July. The mean clutch size was 3.29±0.77 (range 1-4, n=19) that differed between the dry ploughed field clutches (3.4±0.70, range: 2-4, n=10) and wet pool/pond sites (2.78±1.09, range: 1-4, n=9). In the dry ploughed fields, the nest scrapes were lined mainly with the wheat rootlets/ straw pieces only. However, the nest material used in/around ponds and pools included predominantly dry twigs, decaying leaves and some thermocol chips. The egg length, breadth, weight, egg shape index and volume (n=54) measured 42.22±2.50 mm, 30.71±1.13 mm, 19.77±2.34 gm, 72.88±3.19 and 20.39±2.36 cm3, respectively. The eggs hatched mostly synchronously after biparental incubation period of 25 or 26 days (n=4). As per traditional method, only 20.34% (12 out of 59 eggs) of the eggs hatched successfully and the hatching success calculated as per the Mayfield Method showed that it was only 2.07% in post-harvest field sites and 36.26% in non-agricultural sites (shallow water pools and edge waters of village ponds). The use of polluted sites as nesting grounds has been opined as a habitat shift and an adaptation in process
The hygiene hypothesis for allergy – conception and evolution
Authors: Perkin Michael R , Strachan David P
Published: November 2022

In 1989, a short paper entitled “Hay fever, hygiene and household size” observed that British children from larger families were less likely to develop hay fever and suggested that this could be because early exposure to infection prevents allergy. This sibship size association for hay fever, since replicated many times in Britain and other affluent countries and confirmed by objective measures of atopy, prompted what has come to be known as the “hygiene hypothesis for allergy”, although that term was not specifically used in the 1989 paper. The present paper reviews the historical roots of the “hygiene hypothesis” and charts its development over more than 30 years. Initial scepticism among immunologists turned to enthusiasm in the mid-1990s as the Th1/Th2 paradigm for allergic sensitisation emerged from animal experiments and the concept of “immunological old friends” became popular from the early 2000s. From the late 1990s, observations of reduced allergy risk among children of anthroposophic families and those brought up on farms suggested that the sibship size effects formed part of a broader range of “hygiene-related” determinants of allergy. Children from large families with farming exposure have approximately sixfold reduction in prevalence of hay fever, indicating the potential strength and epidemiological importance of these environmental determinants. During the 21st century, a wide range of specific microbial, environmental and lifestyle factors have been investigated as possible underlying mechanisms, but sadly none have emerged as robust explanations for the family size and farming effects. Thus, while the “hygiene hypothesis” led to a fundamental reappraisal of our relationship with our microbial environment and to the concept that early exposure, rather than avoidance, is beneficial for developing a healthy immune system, the underlying mechanism for variations in allergy prevalence with family size remains, in Churchillian terms, “a riddle wrapped in a mystery inside an enigma”.
Enhancing the electrochemical performance of TiO2 based material using microwave air plasma treatment with an ECR cavity
Authors: Swaroop Ram , Rani Pinki , Jamwal Gaurav , Sabavath Gopikishan , Kumar Haldhar , Jewariya Yogesh
Published: November 2022

The microwave-based plasma treatment facility at the Central University of Punjab Bathinda (CUPB) based on 2.45 GHz has been used to investigate the impact on the electrochemical performance of TiO2. This was accomplished by treating a number of pellets of TiO2 sample material with microwave plasma at an input power of 80 W. The palette is subjected to microwave plasma treatment at 30-, 60-, 80-, and 100-s intervals. Many such characterization methods, including UV-visible spectroscopy, FTIR, XRD, and FESEM, have been applied to the study of the impact of plasma treatment on other physical and chemical properties in the context of untreated pellets. In the 80-s plasma treatment, the FTIR study showed that the (O-Ti-O) vibration band at 500–900 cm−1 was wider than other bands. The UV results showed that an 80-s plasma treatment decreased the sample’s band gap by 37% and increased the amount of disordered, amorphous material in the sample that had not been treated. XRD studies show that a sample that was treated with plasma for 80 s has low crystallinity and a high disorder (amorphous) factor. The Nyquist plot showed that the electrochemical charge transfer resistance drops from 7 (not treated) to 4 after 80 s of plasma treatment. In a study of electrochemical performance, a sample that was treated with plasma for 80 s has a capacitance that is 35% higher than a sample that was not treated.
Use of N-acetylcysteine as treatment adjuvant regulates immune response in visceral leishmaniasis: Pilot clinical trial and in vitro experiments
Authors: Magalhães Lucas Sousa , Melo Enaldo Vieira , Damascena Nayra Prata , Albuquerque Adriana Cardoso Batista , Santos Camilla Natália Oliveira , Rebouças Mônica Cardozo , Bezerra Mariana de Oliveira , Louzada da Silva Ricardo , de Oliveira Fabricia Alvisi , Santos Priscila Lima , da Silva João Santana , Lipscomb Michael Wheeler , da Silva Ângela Maria , de Jesus Amélia Ribeiro , de Almeida Roque Pacheco
Published: November 2022

This investigation aimed to assess the effect of N-acetylcysteine (NAC) as an adjuvant treatment to alleviate visceral leishmaniasis (VL). The present work includes both blinded randomized clinical intervention and experimentalin vitrostudies. The clinical trial included 60 patients with VL randomly allocated into two groups: a test group (n = 30) treated with meglumine antimoniate plus NAC (SbV + NAC) and a control group (n = 30) treated with meglumine antimoniate only (SbV). The primary outcome was clinical cure (absence of fever, spleen and liver sizes reduction, and hematological improvement) in 180 days. The cure rate did not differ between the groups; both groups had similar results in all readout indices. The immunological parameters of the patients treated with SbV + NAC showed higher sCD40L in sera during treatment, and the levels of sCD40L were negatively correlated with Interleukin-10 (IL-10) serum levels. In addition, data estimation showed a negative correlation between the sCD40L levels and the spleen size in patients with VL. For thein vitroexperiments, peripheral blood mononuclear cells (PBMCs) or PBMC-derived macrophages from healthy donors were exposed to solubleLeishmaniaantigen (SLA) or infected with stationary promastigotes ofLeishmania infantumin the presence or absence of NAC. Results revealed that NAC treatment of SLA-stimulated PBMCs reduces the frequency of monocytes producing IL-10 and lowers the frequency of CD4+ and CD8+ T cells expressing (pro-)inflammatory cytokines. Together, these results suggest that NAC treatment may modulate the immune response in patients with VL, thus warranting additional investigations to support its case use as an adjuvant to antimony therapy for VL.
Gut microbiota signature as predictors of adverse outcomes after acute ischemic stroke in patients with hyperlipidemia
Authors: Chen Jiaxin , Chi Beibei , Ma Jiaying , Zhang Junmei , Gu Qilu , Xie Huijia , Kong Yu , Yao Shanshan , Liu Jiaming , Sun Jing , Chen Songfang
Published: November 2022

Introduction

The alterations of gut microbiota have been associated with multiple diseases. However, the relationship between gut microbiota and adverse outcomes of hyperlipidemic stroke patients remains unclear. Here we determined the gut microbial signature to predict the poor outcome of acute ischemic stroke (AIS) with hyperlipidemia (POAH).

Methods

Fecal samples from hyperlipidemic stroke patients were collected, which further analyzed by 16s rRNA gene sequencing. The diversity, community composition and differential gut microbiota were evaluated. The adverse outcomes were determined by modified Rankin Scale (mRS) scores at 3 months after admission. The diagnostic performance of microbial characteristics in predicting adverse outcomes was assessed by receiver operating characteristic (ROC) curves.

Results

Our results showed that the composition and structure of gut microbiota between POAH patients and good outcome of AIS with hyperlipidemia (GOAH) patients were different. The characteristic gut microbiota of POAH patients was that the relative abundance of Enterococcaceae and Enterococcus were increased, while the relative abundance of Lachnospiraceae, Faecalibacterium, Rothia and Butyricicoccus were decreased. Moreover, the characteristic gut microbiota were correlated with many clinical parameters, such as National Institutes of Health Stroke Scale (NIHSS) score, mean arterial pressure, and history of cerebrovascular disease. Moreover, the ROC models based on the characteristic microbiota or the combination of characteristic microbiota with independent risk factors could distinguish POAH patients and GOAH patients (area under curve is 0.694 and 0.971 respectively).

Conclusions

These findings revealed the microbial characteristics of POAH, which highlighted the predictive capability of characteristic microbiota in POAH patients.
Relationship between the neutrophil to high-density lipoprotein cholesterol ratio and severity of coronary artery disease in patients with stable coronary artery disease
Authors: Gao Jie , Lu Jun , Sha Wenjun , Xu Bilin , Zhang Cuiping , Wang Hongping , Xia Juan , Zhang Hong , Tang Wenjun , Lei Tao
Published: November 2022

Objective

To evaluate the link between the neutrophil to HDL-C ratio (NHR) and the degree of coronary stenosis in patients with stable coronary artery disease (CAD).

Materials and methods

Totally 766 individuals who attended our clinic for coronary angiography between January 2019 and January 2021 were included in this study. The participants were divided into two groups, including the CAD group and control group. Spearman correlation analysis was used to investigate the association between NHR and Gensini score and logistic regression analysis was performed to determine the influence of NHR on CAD and severe CAD. Receiver operating characteristic (ROC) curve was constructed to analyze the predictive value of NHR for severe CAD.

Results

The CAD group had a substantially higher median NHR than the control group (3.7 vs. 3.2, P < 0.01). There was a positive correlation between NHR and Gensini score, as well as the frequency of coronary artery plaques. Logistic regression demonstrated that NHR was an independent contributor for CAD and severe CAD. In ROC analysis, the area under the ROC curve (AUC) for NHR was larger than that for neutrophil, HDL-C or LDL-C/HDL-C, and the differences were statistically significant (all P < 0.05). The NHR limit that offered the most accurate prediction of severe CAD according to the greatest possible value of the Youden index, was 3.88, with a sensitivity of 62.6% and a specificity of 66.2%.

Conclusion

NHR was not only associated with the occurrence and seriousness of CAD, but also a better predictor of severe CAD than neutrophil, HDL-C or LDL-C/HDL-C.