bluuebunny/crossref_metadata_2025 huggingface dataset:
مستوى الممارسات التدريسية لأعضاء هيئة التدريس بجامعة إقليم سبأ في ضوء مهارات القرن الحادي والعشرين
Authors: سراج يحيى عبدالله , الحبيشي عبدالرحمن زيد
Published: January 2025

هدف البحث الى تقييم مستوى الممارسات التدريسية لدى أعضاء هيئة التدريس بجامعة إقليم سبا في ضوء مهارات القرن الحادي والعشرين ومعرفة أثر التخصص على مستوى هذه الممارسات.
ولتحقيق ذلك اتبع البحث المنهج الوصفي، حيث قام الباحثان بتطوير استبانة مكونة من (44) فقرة تعكس قائمة مستوى الممارسات التدريسية لدى أعضاء هيئة التدريس بجامعة إقليم سبا في ضوء مهارات القرن الحادي والعشرين مضمنة في ثلاثة مجالات رئيسة وهي: (مهارات التعلم والابتكار والإبداع - مهارات الثقافة الرقمية والإعلام –مهارات الحياة والمهنة)، وبعد التحقق من صدقها وثباتها، تم توزيعها إلكترونيا على عينة البحث المكونة من(66) فرداً، وهم رؤساء الأقسام وعمداء الكليات والمراكز ونوابهم ورئاسة الجامعة، كونهم المسؤولين المباشرين عن أعضاء الهيئة التدريسية في الجامعة، وقد تم إجراء التحليلات الإحصائية المناسبة.
وتوصلت النتائج الى أن درجة مستوى الممارسات التدريسية لدى أعضاء هيئة التدريس الجامعي في ضوء مهارات القرن الحادي والعشرين جاءت بدرجة عالية بصفة عامة، كما بينت نتائج البحث عدم وجود فروق ذات دلالة إحصائية في استجابات عينة البحث حول مستوى ممارسات أعضاء هيئة التدريس الجامعي في ضوء مهارات القرن الحادي والعشرين، تعزي لمتغيرات التخصص. وفي ضوء نتائج البحث قدم الباحثان عددا من التوصيات والمقترحات أهمها الاهتمام بالتنمية المهنية لأعضاء هيئة التدريس وفق احتياجات مدروسة.
 
The research aimed to evaluate the level of teaching practices of faculty members at the university of Saba Region in the light of the 21th century skills. As well as, it aimed to discover the impact of the major for these practices.
For achieving that, the research adopted the descriptive method. The researchers used a questionnaire consisting of (44) statements that clarified the list of teaching practices level of faculty members at university of Saba Region in the light of the 21th century skills. The questionnaire consisted of three main domains: (the first domain was: learning, innovation, and creativity skills), (the second domain was: digital knowledge and media skills), (the third domain was: life and profession skills). After verifying its reliability and validity, it was distributed electronically to the research’s sample which consisted of (66) member. They were the heads of departments, deans of faculties, their deputies, and the presidency of the university as they were the direct officials of the faculty members of the university. Then, appropriate statistical analyses were conducted.
            The research resulted that, the degree of teaching practices level of the faculty members at the university, in the light of the 21th century skills, was in a high degree in general. Also, the research pointed out that, there were no statistically significant differences in the sample’s responses about the level of practices of faculty members at the university in the light of the 21th century skills related to specialization variables. Under the results, the researchers presented several suggestions and recommendations. The most important one was paying attention to the professional development for faculty members according to examined needs.
الدور المُعدِّل لإدارة التكاليف في العلاقة بين سيجما ستة والقيمة المضافة في ظل توسيط الخدمات الهندسية الاستشارية
Authors: عبد الحميد محمود عبد المعطي هاشم , محمود ماجدة جمال حسين
Published: January 2025

هدفت الدراسة لبيان الدور المُعدِّل لإدارة التكاليف في العلاقة بين سيجما ستة والقيمة المضافة في ظل توسيط الخدمات الهندسية الاستشارية بوزارة البنى التحتية والتنمية العمرانية بالولاية الشمالية، واستخدمت المنهج الوصفي التحليلي والمنهج التاريخي، وتمثلت عينة الدراسة في المهندسين بعدد (50) مفردة، وتوصلت الدراسة إلى تُعدِّل إدارة التكاليف العلاقة بين سيجما ستة والقيمة المضافة بقيمة تغير في معامل التحديد (0.212)، وتتوسط الخدمات الهندسية الاستشارية العلاقة بين سيجما ستة والقيمة المضافة بتأثير غير مباشر (0.34)، وأوصت الدراسة بضرورة توعية القيادة والمهندسين بأهمية إدارة التكاليف وسيجما ستة والخدمات الهندسية الاستشارية والقيمة المضافة بالوزارة.
 
 The study aimed to investigate the moderator role of cost management in the relationship between six sigma and additive value under the mediation of consulting engineering services at Ministry of Infrastructure and Urban Development in the Northern State of Sudan. The study adopted the descriptive analytical method and the historical method. The study sample consisted of (50) engineers. As The study resulted the cost management moderator in the relationship between six sigma and additive value with a change in the determination coefficient of (0.212).The consulting engineering mediates the relationship between six sigma and additive value with an indirect effect of (0.34). The study recommended that, there is a need to increase the awareness of leadership and engineers at the ministry about the importance of cost management, six sigma, consulting engineering services and additive value.
Gender Discrimination against Women in Yemeni Proverbs
Authors: al-Hussami Ahmed Abdullah , al-Hiba Mohammed
Published: January 2025

Proverbs have always reflected considerable social, cultural and practical significance. They acquire their importance as social and cultural traditions, practices and even determinates of individual as well as collective social attitudes. Proverbs also obtain worth and value as indicators of gender power relations between male and female community members. Through language and with its help, proverbs could showcase how a woman in any particular human community, for instance, is portrayed, represented, socially perceived and treated, and very likely stereotyped by the male component of that community. Hence, the current research study investigates Yemeni proverbs with relation to women. In terms of its methodology, the study adopts and follows a feminist critical perspective to examine traditional representations of women in the Yemeni proverbs under question. It more particularly negotiates the image and status of Yemeni women as represented through such traditional words of wisdom. The study assumes—and accordingly argues and demonstrates—that women in the Yemeni traditional heritage of proverbs are stereotyped, discriminated against, and sometimes even humiliated in a variety of ways.
 
لقد عكست الأمثال دائمًا أهمية اجتماعية وثقافية وعملية كبيرة. وذلك أنها تكتسب أهميتها باعتبارها تقاليد وممارسات اجتماعية وثقافية وحتى محددات للمواقف الاجتماعية الفردية والجماعية. كما تكتسب الأمثال قيمة كمؤشرات لعلاقات القوة بين الجنسين بين أفراد المجتمع من الذكور والإناث. ومن خلال اللغة وبمساعدتها، يمكن للأمثال أن توضح ، على سبيل المثال، كيف يتم تصوير المرأة في أي مجتمع بشري معين وتمثيلها، وفهمها ومعاملتها اجتماعيًا، حيث من المحتمل جدًا أن يتم تقديمها في صورة نمطية من قبل العنصر الذكوري في ذلك المجتمع. ومن هنا فإن الدراسة البحثية الحالية تتقصى ذلك في الأمثال اليمنية المتعلقة بالمرأة. ومن حيث منهجيتها، قان الدراسة الحالية تتبنى وتتبع منظوراً نقدياً نسوياً لدراسة التمثيلات التقليدية للمرأة في الأمثال اليمنية محل البحث. كما تناقش الدراسة وبشكل خاص صورة ومكانة المرأة اليمنية كما يتم تمثيلها من خلال هذه الكلمات التي تمثل الحكمة التقليدية. وتفترض الدراسة - ومن ثم تجادل وتثبت - أن المرأة في التراث اليمني التقليدي للأمثال تتعرض للتنميط والتمييز، بل وأحياناً الإذلال بطرق متنوعة.
الهدي النبوي في غرس القيم وتنميتها؛ الخصائص المنهجية، والأساليب العملية
Authors: ادعيكـل عبد الرزاق
Published: January 2025

يسعى هذا البحث إلى بيان الهدي النبوي في غرس وترسيخ القيم الإسلامية في النفوس للبلوغ بها إلى أسمى مراقي التزكية؛ قصد النهل من هذا المعين الصافي لبعث القيم في نفوس الناس من جديد، وإحياء ما اندرس منها وخَلِق أو كاد، فالتوسل بالسيرة النبوية في هذا الشأن أمر ضروري؛ كيف لا وهي سيرة من أدبه  ربه فكان صلى الله عليه وسلم أحسن الناس خلقا؟ فبعث لإتمام مكارم الأخلاق، فكان خير مرب، وقد جمع هديه صلى الله عليه وسلم من الخصائص أعظمها، ومن الأساليب أنفعها، غير أن الناس  متفاوتون في الاستفادة من هديه صلى الله عليه وسلم، كما أن النظر في كثير من الجهود التي بذلت في هذا الباب يفيد أن معظمها مفتقر إلى توجيهات علمية منهجية تمكنها من تجاوز أوجه القصور؛ فلذلكم  جاء البحث لبيان ثلاثة أمور عظيمة النفع؛ أولها: الخصائص العامة التي تميز بها الهدي النبوي في تنمية القيم، ثانيها: الأساليب العملية المتنوعة التي سلكها صلى الله عليه وسلم لترسيخ القيم، وثالثها: بعض أوجه القصور في تنمية القيم وتثبيتها في الواقع المعيش.
أراجيز عبد الله بن رواحة
Authors: مصيباح أحمد كرامة سالم
Published: January 2025

هدف البحث إلى دراسةِ أراجيز عبد الله بن رواحة دراسةٍ أسلوبيّة، بمستوياتِهِ الثلاثةِ الإيقاعيِّ والتصويريِّ والتركيبيِّ. وقد اعتمد البحث المنهجَ التحليليَّ الوصفيَّ في تحقيقِ أهدافِها.
وجاء هذا البحث في مقدمةٍ وثلاثةِ مباحث، تحدثت في المقدمةِ عن أهميةِ الموضوعِ، وأهدافِه، وأسبابِ اختيارِه، ومنهج البحث.
ففي المبحثُ الأولُ: تناولَ عناصرَ الإيقاعِ في أراجيز ابن رواحة، ففي الإيقاعِ الداخليِّ تتبع البحث أوزان أراجيز ابن رواحة التي جاءت كلها مشطورة فدرس أوزانها والأغراض التي قيلت لها، ثم درسَ القوافيَ وأنماطَها وأنواعَ حرفِ الرويّ؛ فقد استعملَ ستة أحرف وكانت كلها مجهورة ومخرجها من طرف اللسان في الغالب؛ ليتناسب مع مقام الفخر وتعدد الصفات الحميدة في الممدوح، وتمَّ رصدُ بعض مظاهرِ القافيةِ العامةِ كالإيطاءِ والإكفاء فتعّرفَ وجودَها في نصِّ ابن رواحة في القافيةِ، وتناولَ في درسِ الإيقاعِ الداخليِّ إيقاع الألفاظِ.
والمبحث الثاني: اهتمّ بدراسةِ الصورةِ الفنيّة في شعره؛ فدرسَ مصادرَ الصورةِ: الطبيعي، والإنساني، والثقافي، وبحثَ بنيةَ الصورةِ البيانيّةِ من تشبيهٍ واستعارةٍ وكنايةٍ.
وأمّا المبحث الثالثُ: فقد تخصّصَ في دراسةِ الظواهرِ التركيبيّةِ في أراجيز ابن رواحة، فبحثَ في التعابيرِ وتركيبِ الجملةِ، وتمثّلَ في ثلاثِ ظواهرَ أسلوبيّة هي: التقديمُ والتأخيرُ، والحذفُ، والزيادةُ،، كما تناولَ الأساليبَ الإنشائيّة، وبيّنت الدراسةُ نزعةَ ابن رواحة في استعمالِ هذه الأساليبِ بعيدًا عن دلالاتِها الوضعيّةِ في اللّغة، إلى دلالاتٍ بلاغيّةٍ أخرى أفادت سياقَ النصّ وأثرت معناه.
Bleomycin-induced Pulmonary Toxicity in a Patient with Hodgkin Lymphoma: A
Case Report
Authors:   Honorary International Faculty, AJ Institute of Medical Sciences and Research Centre, Karnataka, Mangalore, India, Vityala Yethindra , Praneeth Duvvuri Sai , Chaitanya Meduri Krishna , Shantaram Manjula , Jaladi Pavani
Published: January 2025

Bleomycin is an antineoplastic drug used to treat various types of cancer. It can cause pulmonary toxicity (PT) with different patterns on chest computed tomography (CT), including diffuse alveolar injury, organized pneumonia, nonspecific interstitial pneumonia, and bronchiolitis. The exact mechanism of PT remains unclear, but it is related to the generation of active bleomycin radicals in the absence of oxygen. Currently, the only effective treatment for PT is timely administration of corticosteroids to prevent severe respiratory failure and fibrosis. A case of a patient with stage IIIB Hodgkin's lymphoma who experienced clinical deterioration attributed to the toxic effects of bleomycin is presented. The patient's chemotherapy regimen was changed, and the AVD regimen was continued without bleomycin, along with oral steroid treatment for four weeks. After seven weeks, the patient's symptoms improved significantly, and imaging revealed improvement.
Multiomics: Concepts, Methods and Applications
Authors:   Associate Research Professor, Department of Internal Medicine, Division of Endocrinology, Diabetes and Metabolism, Center for Diabetes and Cardiovascular Research, Dalton Cardiovascular Research Cente, R Aroor A
Published: January 2025

Multiomics is a high-throughput technology with multilayered system biology approach incorporating bioinformatic analysis of the data. At present it includes genomics, epigenomics, transcriptomics, proteomics, metabolomics, and gut microbiomics with advancement to the level of single cell analysis. Multiomics is an advancing approach (1) to understand the pathobiology of disease, (2) to identify sensitive biomarkers for the diagnosis of diseases as well as in monitoring and (3) to identify disease specific targets to treat the patient in the context of precision medicine as targeted therapeutics. In the present review, a brief account of various multiomic techniques is considered and relevant examples are pondered to reflect their applications in both preclinical and clinical translational research.
Kesesuaian Perpustakaan Desa di Desa Bukit Intan Makmur Dengan Standar Nasional Perpustakaan
Authors: Komarudin  , Santoso Budhi
Published: January 2025

Pendahuluan. Penelitian ini bertujuan untuk menilai kesesuaian Perpustakaan Desa di Desa Bukit Intan Makmur dengan Standar Nasional Perpustakaan Desa sebagaimana diatur dalam Peraturan Kepala Perpustakaan Nasional Republik Indonesia Nomor 6 Tahun 2017. Penelitian ini bertujuan untuk mengevaluasi sejauh mana standar tersebut telah dipenuhi dan mengidentifikasi kendala-kendala yang dihadapi.
Metode Pengumpulan Data. Penelitian ini menggunakan metode kualitatif dengan pendekatan deskriptif. Data dikumpulkan melalui wawancara mendalam, observasi, dan dokumentasi dari informan yang terdiri atas pengelola perpustakaan, perangkat desa, dan masyarakat pengguna perpustakaan. Analisis data dilakukan dengan teknik reduksi data, penyajian data, dan penarikan simpulan.
Hasil dan Diskusi. Hasil penelitian menunjukkan bahwa beberapa aspek perpustakaan telah memenuhi standar, seperti koleksi yang mencakup berbagai jenis dan ruang perpustakaan yang tertata dengan baik. Namun, masih ditemukan beberapa ketidaksesuaian, antara lain jumlah koleksi belum mencapai batas minimal yang ditetapkan, alokasi anggaran pengadaan bahan perpustakaan belum optimal, dan jam buka perpustakaan yang masih terbatas. Pola pelayanan perpustakaan masih berbasis di tempat dan belum mencakup layanan perpustakaan keliling.
Simpulan. Kesimpulan dari penelitian ini adalah bahwa Perpustakaan Desa di Desa Bukit Intan Makmur telah berupaya memenuhi sebagian besar standar nasional, namun masih diperlukan perbaikan dan pengembangan di beberapa aspek untuk meningkatkan kualitas layanan dan fungsi perpustakaan sebagai pusat informasi, pembelajaran, dan rekreasi masyarakat.
Problematika dan Tantangan dalam Penyajian Koleksi Kitab Klasik di Perpustakaan Perguruan Tinggi Islam
Authors: Jamilah Asyfiya Qurratal , Masruri Anis , Pratama Bagas Aldi , Rifauddin Machsun
Published: January 2025

Pendahuluan Koleksi kitab klasik seringkali menjadi fokus utama dalam warisan intelektual dan budaya, namun mengelola koleksinya melibatkan beberapa masalah yang memerlukan penanganan strategis. Perpustakaan perguruan tinggi Islam sering kali menghadapi kendala terkait usia kitab, nilai historis yang tinggi, dan kerapuhan fisiknya yang rentan terhadap kerusakan.
Metode Pengumpulan Data. Peneliti menggunakan tinjauan pustaka untuk menganalisis informasi yang dikumpulkan dari buku, jurnal, dan artikel ilmiah yang berkaitan dengan topik penelitian. Data yang terkumpul kemudian dianalisis menggunakan model Miles dan Huberman dengan reduksi data, penyajian data, dan penarikan kesimpulan.
Hasil dan Diskusi. Pemeliharaan fisik, aksesibilitas, penggunaan teknologi, dan digitalisasi menjadi permasalahan dalam pengelolaan koleksi kitab klasik. Digitalisasi koleksi, pengemasan ulang informasi, kolaborasi dengan para ahli, dan peran strategis pustakawan dalam pengelolaan koleksi dan aksesibilitas diperlukan untuk menjamin nilai intelektual dan kekayaan budaya yang terkandung dalam buku klasik untuk generasi mendatang.
Simpulan. Keterlibatan aktif pustakawan diperlukan untuk memastikan nilai intelektual koleksi kitab klasik di perpustakaan universitas Islam dapat diakses secara berkelanjutan.
Pemberian Zat Pengatur Tumbuh Ekstrak Bawang Merah Terhadap Pertumbuhan Akar Setek Lada(Piper ningrum L.) Varietas Kerinci
Authors: Basri Hasan , Setyoko Ujang
Published: January 2025

Pendahuluan. Lada (Piper nigrum L.) merupakan salah satu tanaman rempah paling tua dan populer didunia. Perbanyakan  lada dengan setek membutuhkan waktu kurang lebih dua bulan untuk pertumbuhan akar. Salah satu cara untuk memacu terbentuknya akar yaitu dengan cara pemberian Zat Pengatur Tumbuh (ZPT) alami. Penelitian ini dilaksanakan untuk mengetahui pengaruh pemberian konsentrasi ekstrak bawang merah terhadap pertumbuhan setek lada.
Metode Pengumpulan Data. Penelitian ini dilaksanakan pada bulan Februari sampai dengan bulan Mei 2023 yang bertempat di lahan Politeknik Negeri Jember (-8,1590464, 113,7240660). Penelitian ini dilakukan dengan menggunakan Rancangan Acak Lengkap (RAL) non faktorial. Faktor yang digunakan yaitu berbagai konsentrasi ekstrak bawang merah dengan 5 level perlakuan pada konsentrasi, K0 = 0% (kontrol), K1 = 12,5%, K2 = 25%, K3 = 37,5 %, K4 = 50%. Setiap perlakuan terdiri dari 4 ulangan, dengan total 20 unit dan setiap unit terdiri dari 10 setek. Data yang telah didapatkan dari hasil pengujian kemudian dianalisis menggunakan uji F (Anova). Apabila terdapat pengaruh nyata maka dilakukan uji lanjut menggunkan BNT pada taraf 5%. Parameter pengamatan meliputi jumlah akar, panjang akar (cm), volume akar (ml).
Hasil dan Diskusi. Hasil penelitian ini menunjukkan bahwa  konsentrasi ektra bawang merah berbeda sangat nyata terhadap jumlah akar, panjang akar,dan volume akar berbeda tidak nyata pada semua parameter pengamatan.
Simpulan. Berdasarkan hasil penelitian di atas dapat disimpulkan bahwa pemberian ektrak bawang merah terhadap jumlah akar, panjang akar, dan volume akar pada 10 minngu setelah tanam berpengaruh berbeda tidak nyata.
The Political Poetics of Contrastive Identifications: Scripting Ongoing Events Through Master/Counter Positioning in Populist Political Speech
Authors: Rautajoki Hanna
Published: January 2025

The article reports an empirical inquiry into the rhetorical use of master/counter juxtapositions in narrating an ongoing scene of political action. Drawing on the studies of institutional interaction, it investigates the institutional setting of public political speeches, focusing on the empirical example of Donald Trump’s public speech in the rally after the election results and just before the violent invasion of the United States Capitol on January 6, 2021. My research approaches master/counter positioning as a multilayered relational constellation of identifications mobilized in the telling and deployed strategically for specific institutional purposes. I am interested in counter-narratives as interpretative discursive frames superimposed on surrounding socio-material circumstances to refute an alternative (pre-existing and prevailing) interpretation of reality. My take on the concept as a multifaceted rhetorical resource subsumes the aspects of an act of contestation, a breach of cultural orders, and a mission towards emancipation, albeit in a slightly modified version of the conventionalized definitions. In the context of political interaction, that is, in institutional activities connected to ongoing processes in policy-making and governance, counter-narratives are world-breaking but they are also world-making in a decidedly concrete consequential manner, firstly, by building on institutional continuities, virtues, and legitimacies, and secondly, by addressing recipients as co-actors, projecting identifications on them and expecting them to assume a role in the political participation field at hand. Applying tools from small story research, membership categorization analysis, epistemic governance and narrative positioning analysis, I explore the purposeful evocation of contrastive storylines in political rhetoric. The article aims to shed light on the argumentative use of counter-narratives in a political line of action.
Multilevel DC-AC Converter Interface with Solar Panels
Authors: Cao Yue
Published: January 2025

This paper presents a single-phase 11-level (5 H-bridge) cascaded multilevel DC-AC converter that has implemented a Phase Locked Loop (PLL) and Maximum Power Point Tracking (MPPT) with 5 separate solar panel DC sources. This topology upgrades the conventional 3-level Pulse Width Modulation (PWM) controlled converter with advantages such as smoother output waveforms, more flexibility in voltage range, smaller filter size, and switching angle control. Simulation results of voltage synchronization using PLL and experimental setup and results implementing the entire converter interface are also presented.
The valorization of flotation tailings in terms of the concept of the circular economy: characterization, environmental risk assessment, and waste utilization routes
Authors: Mikoda Bartosz , Potysz Anna , Siepak Marcin , Kmiecik Ewa
Published: January 2025

Flotation tailings originating from copper ore processing were evaluated in terms of chemical and mineralogical features, leaching, and resource potential. The results demonstrated that flotation tailings show varying degrees of the leachability of elements when exposed to different pH conditions (2–13); the Zn, Cu and Co leachabilities decrease as pH increases, whereas Mo, Ag and Sb revealed U-shaped leaching trend as a function of pH. Flotation tailings were found to be fairly reactive when exposed to water leaching and rainfall conditions. The environmental risk analysis demonstrated Zn to be the most susceptible element to liberation from the flotation tailings studied. Recovery tests demonstrated sulfuric acid to be slightly more efficient extracting agent as compared to citric acid. Hybrid approach to metal recovery was rather unsuitable for studied tailings due to lower extraction yield (not exceeding 20%) as compared to chemical treatment (not exceeding 40%).
Reduction of DNA Topoisomerase Top2 reprograms the epigenetic landscape and extends health and life span across species
Authors: Zhu Man , Ma Meng , Luo Lunan , Li Feiyang , Zhang Jiashun , Pan Yan , Yang Lu , Xiao Ying , Wang Ziyan , Xian Bo , Zheng Yi , Li Hao , Yang Jing
Published: January 2025

DNA topoisomerases are essential molecular machines that manage DNA topology in the cell and play important roles in DNA replication and transcription. We find that knocking down the enzyme Topoisomerase Top2 or its mammalian homolog Top2b increases the life span of
S. cerevisiae
,
C. elegans
, and mice. Top2b reduction also extends the health span of mice and alleviates the pathologies of aging in multiple tissues. At the cellular/molecular level, Top2b reduction attenuates the major hallmarks of aging, such as cellular senescence, de-regulated nutrient sensing, epigenetic alteration, and lysosomal biogenesis. We observed that Top2b reduction significantly changes the epigenetic landscape in various mouse tissues toward those of the young animals, and differentially down-regulates genes with active promoter and high expression. Our observations suggest that Top2 reduction confers longevity effect across species via a conserved mechanism, and may be used as a novel therapeutic strategy for countering aging.
How a gene fuels ear infections
Authors: Delmaghani Sedigheh , El-Amraoui Aziz
Published: January 2025

The DYRK1A enzyme is a pivotal contributor to frequent and severe episodes of otitis media in Down syndrome, positioning it as a promising target for therapeutic interventions.
Evaluating Study Design Rigor in Preclinical Cardiovascular Research: A Replication Study
Authors: Jimenez Isaiah C , Montenegro Gabrielle C , Zahiri Keyana , Patel Damini , Mueller Adrienne
Published: January 2025

Methodological rigor remains a priority in preclinical cardiovascular research to ensure experimental reproducibility and high-quality research. Limited reproducibility diminishes the translation of preclinical discoveries into medical practice. In addition, lack of reproducibility fosters uncertainty in the public’s acceptance of reported research results.We evaluated the reporting of methodological practices in preclinical cardiovascular research studies published in leading scientific journals by screening articles for the inclusion of the following study design elements (SDEs): considering sex as a biological variable, randomization, blinding, and sample size power estimation. We screened for these SDEs across articles regarding preclinical cardiovascular research studies published between 2011 and 2021. We replicated and extended a study published in 2017 by Ramirez et al. We hypothesized a higher SDE inclusion across preclinical studies over time, that preclinical studies that include human and animal substudies within the same study will exhibit greater SDE inclusion than animal-only preclinical studies, and that a difference exists in SDE usage between large and small animal models.SDE inclusion was low; with 15.2% of animal-only studies including both sexes as a biological variable, 30.4% including randomization, 32.1% including blinding, and 8.2% including sample size estimation. The incorporation of SDEs did not significantly increase over the ten-year timeframe in the screened articles. Randomization and sample size estimation differed significantly between animal and human substudies (corrected p=1.85e-05 and corrected p=3.81e-07, respectively.)Evidence of methodological rigor varies depending on the study type and model organisms used. From 2011-2021, SDE reporting within preclinical studies has not increased, suggesting more work is needed to foster the inclusion of rigorous study design elements in cardiovascular research.
Development of Optimized Liquid Formulations of Azospirillum, Phosphate-Solubilizing Bacteria, and Rhizobium Strains for Enhanced Viability and Shelf Life
Authors: Patil CR , Patil Sandesh Subhas , Sriramareddy Parvati
Published: January 2025

The aim of this study was to evaluate the stability and shelf-life of Rhizobium, Azospirillum, and Pseudomonas striata a Phosphate Solubilizing Bacterium (PSB) in liquid formulations under ambient conditions, with a focus on the impact of various additives on the viability of these microbes over a 12-month period. Liquid formulations of Rhizobium strains NC-92, Sb-120, and Gr-2, Azospirillum, and PSB were prepared with different combinations of additives such as polyethylene glycol (PEG), gum arabic (GA), polyvinylpyrrolidone (PVP), and glycerol. The formulations were stored under ambient conditions, and colony-forming unit (CFU) counts were assessed at regular intervals over the year. The results revealed that formulations with higher concentrations of PVP, GA, and PEG maintained significantly higher CFU counts. Azospirillum formulations, particularly F20, exhibited superior viability, maintaining 2.2 × 10⁷ CFU after 12 months compared to rapid declines in other formulations such as F2, F8, and F16. Rhizobium NC-92 in basal medium + 1% PVP (F1) retained 5.2 × 10⁸ CFU after 12 months, while Sb-120 in basal medium + 1% PVP (T1) demonstrated high stability, maintaining 6.9 × 10⁸ CFU over six months. PSB formulations containing combinations of glycerol, PEG, and PVP also performed better, with the best formulation retaining 6.2 × 10⁸ CFU after 12 months. The study highlights the importance of certain additives such as PVP, GA, and PEG in improving the stability and shelf life of microbial compositions. Optimized formulations significantly increased viability, laying the groundwork for the development of robust biofertilizer solutions.
Lived Experiences of Teachers Implementing Reading Programs in Secondary Schools of Pudtol District
Authors: Rillo April Love Joy A.
Published: January 2025

The goal of this research was to describe the experiences of reading program implementers in  Pudtol District, Province of Apayao as reading program implementers. Employing phenomenological approach among seven teacher participants, in-depth interview was conducted which answered the four fundamental questions. Essential themes were generated out from their responses to the research questions. The findings uncovered the participants’ lived experiences, and from it seven themes emerged: expecting students already know how to read, most students are slow readers, having a hard time implementing reading program to students, able to know the reading level of the students, able to influence students in reading, providing appropriate reading activities and able to know the learner’s capacity in reading. The participants also shared the challenges they encountered as reading program implementers, from which emerged five themes: the absenteeism of learners, learners’ lack of interest, the attendance of learners, providing time in reading implementation, and addition to workload. Further, for the coping mechanisms they revealed ten essential themes: conduct a meeting, prepared reading materials in different reading levels, peer-tutoring, providing differentiated activities, send letters to parents whose child is always absent, home visits, parents and students, students and co-teachers, ask parents to assist their child in reading, and technical assistance from co-teachers Lastly, for the insights, eight themes emerged: use appropriate reading materials, develop time management, be patient, provide more time in reading activities, provide assistance to the reading programs implementers, provide specified time and teacher for reading implementation, improvement on learners’ reading and comprehension skills, and upcoming high school students already know how to read. In view of the above, research and educational practices should continue to evolve to meet the changing needs of students in the new normal. Prioritizing early literacy interventions, continuous development of reading programs, and a coordinated effort to foster strong reading skills among students are essential steps towards a brighter educational future.
Size-Specific Dose Estimate for Chest of Adult Patients in 128- Slice Computed Tomography at Rajavithi Hospital
Authors: Sawarin C.
Published: January 2025

Aims: To determine the patient radiation dose using Size-Specific Dose Estimates (SSDEs) for chest CT in adult patients performed with 128-slice CT technology.
Study Design: A descriptive cross-sectional study was conducted as a retrospective analysis.
Place and Duration of Study: Department of Radiology, Rajavithi Hospital, between April 1 and September 30, 2021.
Methods: We included 500 patients (209 males, 291 females). All patients underwent chest contrast enhancement with a venous phase protocol. The patient radiation dose in terms of SSDE was calculated based on AP+Lat dimensions, effective diameter, and water-equivalent diameter. SSDEs was measured from the middle slice of the scan range. The conversion factors following body size and composition were applied according to the AAPM Reports No. 204 and 220 recommendations. Additionally, the study assessed the effective dose and dose-length product (DLP). Key parameters, including DLP, CTDIvol, effective dose, and SSDEs at the 75th percentile, were evaluated to determine radiation dose levels. These values were then compared with established national and international diagnostic reference levels.
Results: The study found that the mean DLP was 301.74 mGy·cm, CTDIvol was 8.38 mGy, effective dose was 4.22 mSv, SSDE (AP+Lat) was 11.80 mGy, SSDE (Effective Diameter) was 11.86 mGy, and SSDE (Dw) was 12.91 mGy. When compared with reference radiation dose values from Thailand and international standards, the DLP, CTDIvol, and effective dose values were found to be lower than both Thai and international reference values. In contrast, the SSDE (AP+Lat) was also lower than previously reported findings. Additionally, the study found no available comparative data for SSDE (Effective Diameter) and SSDE (Dw).
Conclusion: The comparison of radiation dose values using SSDE across the three methods revealed highly consistent results. The SSDE values obtained from this study can serve as reference levels for the radiation doses received by patients undergoing CT scans at the Radiology Department of Rajavithi Hospital. These values are instrumental in assessing the appropriateness of radiation doses applied during CT imaging and can serve as benchmarks for future dose optimization efforts. Furthermore, this study highlights the significance of evaluating radiation doses in diagnostic imaging, providing valuable baseline data that enhances our understanding of the radiation risks associated with various types of examinations. Further research is warranted to investigate radiation exposure in computed tomography for other body regions.
New Approach: Tabular Fuzzy Arithmetic of the LR Type by Jomatopfe
Authors: Engombangi Jonathan Opfointshi , Makengo Rostin Mabela , Mazoni Grace Nkwese , Tapasa Fernand Mamanya , Tshiseba Cédric Kabeya , Londjiringa Emilien Loranu , Lukenzu Anita Mukawa , Ndimba Samuel Diangitukulu , Binene Camile Likotelo
Published: January 2025

This paper presents a fuzzy approach of LR types, also called LR-type tabular fuzzy arithmetic capable of handling or computing simultaneously the kernels and supports of trapezoidal fuzzy numbers, instead of doing it separately (Advantage of this approach) in order to minimize the tedious steps of alpha-cut based approaches. On the theoretical level, the aim of this article is to explain in a concise and clear manner some basic concepts of fuzzy logic that seem to continue to complicate authors and readers (researchers) in this field, given the important place of this theory in Artificial Intelligence today. Some user interfaces have been created in this article, with the python language, in order to automatically calculate certain results; and especially to minimize the calculation time, in particular of membership degrees, kernels and supports. Trapezoidal fuzzy numbers are transformed into LR form in order to allow a comparative study between the alpha-cut approach with the Jomatopfe LR-type tabular fuzzy arithmetic presented in this paper. We successfully demonstrated the transition from the trapezoidal fuzzy form to the LR type form and vice versa.
After a comparative study between the alpha-cut approach and the tabular fuzzy arithmetic of the LR type, Jomatopfe's LR type arithmetic significantly reduced the complexity of the calculation processes compared to classical methods, which require distinct steps for each element. This fuzzy tabular altimetry is not to be confused with other fuzzy tables operations on membership degrees.
Symmetry Analysis, One-dimensional Optimal System, and Group Invariant Solutions for the Shallow Water Waves of Finite Amplitude in (1+1)-dimensions
Authors: Majhi Pratik , Kumari Sharda , Panja Madan Mohan
Published: January 2025

The Lie group theoretic approach is employed here to obtain inequivalent group invariant solutions of a system of nonlinear partial differential equations (SNLPDEs) in (1+1)-dimensions appearing in the mathematical analysis of shallow water waves of finite amplitude, tsunami waves in particular. It is found that the system of equations admits a five-parameter Lie group of symmetry transformations with a Lie algebra \(\mathcal{G}\) of infinitesimal generators. An optimal set \(\mathcal{OG}_1\) of eighteen one-dimensional subalgebras of \(\mathcal{G}\) has been obtained. Similarity variables corresponding to each member of \(\mathcal{OG}_1\) have been determined and used to reduce the SNLPDEs to the system of ordinary differential equations. Some constants of the motion and inequivalent group invariant solutions have been provided whenever the system of reduced equations is solvable. The solutions to some of the reduced equations and the constants of motion provided here seem novel. Results obtained here may be used to check the accuracy of approximate solutions (grid formation) in the approximation (numerical) scheme.
Connotation of Plant Growth Regulators on Seed Germination
Authors: Chattha Fauzia Anjum , Kousar Samina , Naeem Fatima , Ahmad Soha
Published: January 2025

Seed germination is a complex physiological process influenced by various internal and external factors. The initial requirements for seed germination include suitable temperature (depending on the seed type), moisture, and oxygen. The endosperm serves as a reservoir of food and contains hormones that initiate seed germination. Both endogenous (produced within the seed) and exogenous (externally applied) hormones play a crucial role in germination and the early growth of seedlings. Plant growth activators enhance seed germination and promote growth, while retardants inhibit both germination and growth processes and may induce dormancy. Growth inhibitors, therefore, can be strategically applied to prolong seed viability during storage. Furthermore, various exogenous chemicals are employed to regulate seed and plant growth processes. These hormones and chemicals not only influence germination but also help to determine the seed's chemistry, providing insights into its physiology and predicting its behavior under different conditions.
RODDMS-IoT: A Radar Based Real-Time Moving Object Detection and Distance Measurement System Using IoT for Enhanced Safety
Authors: Huque Md. Tahmidul , Hossain Md. Sabbir , Godhuli Jafreen Jafor , Haque Ehtashamul
Published: January 2025

The main users of RADAR (Radio Detection and Ranging) in its early development for security and monitoring purposes were the navy, the military, the aviation services, as well as the space organizations. Nowadays, the demand of radar is expanding. But it takes a while to detect, has a limited detection area, lacks target specificity due to its wide range, oversensitive, costly, etc. A cheaper, easy and effective alternate solution is to use ultrasonic sensor which use sound waves for detection and ranging. Therefore, this study offers a technique for using the Ultrasonic Sensor (HC-SR04) as RADAR. For the purpose of rotation and movement, the Servo Motor (SG90) is connected to the Ultrasonic Sensor (HCRS04). The SIM808 IoT integrated GPS-GSM module is also utilized to send out SMS notifications for object identification. These components are connected to an Arduino Uno and a Raspberry Pi3 to detect and notify the object. Additionally, the goal of this work is to capturing the distance, direction, and radar pulse duration and object shape simultaneously. An algorithm was used to determine the object's velocity, or its speed toward or away from the radar, in order to acquire the precision. By comparing the actual values with the data acquired by the radar, the accuracy of the measurement of both angle and distance is ensured. There are both metal and non-metal objects used in this study. This work's novelty lies in its ability to accurately detect real-time moving objects and measurement the distance of the objects. Besides proper distance and velocity, a large set of data was taken to find the accuracy of the radar for objects of different shapes. The results show the object detected with its distance and angle in a java based Graphical User Interface (GUI), different ranges of object in cm at which it is detected and the detection notification sent to the admin via SMS.
Textbook Accessibility and Retention in Mathematics and Economics: Insights from Cameroon
Authors: Nkepah Beyoh Dieudone , Fokong Nubonyin Hilda
Published: January 2025

Aims: This study evaluates the impact of the Single Textbook Policy on high school students' retention in Mathematics and Economics in Cameroon. The policy, implemented to standardize educational resources, has raised concerns about its effectiveness in enhancing students’ retention of key concepts. It seeks to compare retention scores among students using no textbooks, one official textbook, or multiple textbooks, with a focus on subject-specific and gender-based differences.
Study Design: The research employed a causal-comparative design to examine the retention of mathematical and economic concepts among students under varying textbook accessibility conditions.
Place and Duration of Study: The study was conducted in Cameroon, focusing on students who had completed their Advanced Level examinations and were registering for university. The duration spanned the period during the registration into the university of Bamenda for the 2024/2025 academic year.
Methodology: Data were collected from 300 high school students using a structured assessment of their retention of mathematical and economic concepts. Students were grouped based on their textbook usage: no textbooks, one official textbook, or multiple textbooks. Gender differences in retention were also analyzed. Means and standard deviations were used to answer the research questions while independent samples t-test and ANOVA were used to test the hypotheses at the 5% level of level significance.
Results: The analysis revealed significant differences in retention scores based on the number of textbooks used. Students who used multiple textbooks demonstrated higher retention scores compared to those using a single official textbook or no textbooks. Gender differences did not significantly impact retention in either Mathematics or Economics.
Conclusion: The study suggests that increasing access to multiple textbooks enhances students’ retention of mathematical and economic concepts. These findings question the efficacy of the Single Textbook Policy and recommend that educational strategies in Cameroon’s secondary schools incorporate diversified learning resources to improve academic outcomes.
Strategies for Ecotourism Development at Puncak Tangke Tabu, Sempajaya Village, Berastagi, Karo Regency
Authors: P. Solo , Lubis Satia Negara , Aritonang Evawany Yunita
Published: January 2025

This study utilizes a qualitative descriptive approach with SWOT analysis to explore the development potential of Puncak Tangke Tabu, located in Sempajaya Village, Berastagi District, Karo Regency, as an ecotourism destination. The qualitative descriptive approach was chosen to capture the rich, contextual insights necessary for understanding the area's unique characteristics and development challenges. Data were collected through observation, interviews, and documentation. Findings indicate that while the site possesses strong natural and cultural appeal, such as pristine landscapes and active community involvement through the Rimba Merga Silima Cooperative, its growth is hindered by challenges like limited promotion, insufficient infrastructure, and low community awareness of ecotourism management. Strengths, such as its strategic location and tourist interest in nature-based attractions, can be leveraged to mitigate weaknesses and threats, including natural disasters and illegal fees. Strategic recommendations include implementing digital marketing campaigns to enhance visibility, improving accessibility and amenities to cater to diverse visitor needs, and fostering stakeholder collaboration to ensure sustainable development. Specific policy implications involve the need for government support in regulating tourism practices, providing funding for infrastructure development, and incentivizing community participation in tourism management. With effective implementation of these strategies, Puncak Tangke Tabu can serve as a model for community-based ecotourism in Indonesia, promoting environmental conservation, local cultural preservation, and economic empowerment of the local community.
Renewable Energy In Nigeria; A Backbone For Agriculture In A Climate Change Era
Authors: Onyebuchi Anuka, Anthony , Sanubi Franklins , Etemike Lazarus
Published: January 2025

Prior to the advent of the petroleum era in Nigeria, agriculture served as a key pillar of economic sustainability,
significantly contributing to the nation’s GDP and income. However, climate change now poses significant threats
to the sustainability of food production. To address these challenges, renewable energy solutions are essential to
reduce ecosystem vulnerability and advance technological innovations for food security, particularly in
underdeveloped and developing nations like Nigeria. This study explores the dynamics of climate change, the
pursuit of renewable energy, and food security in Nigeria. Employing a historical research design, the study relied
on secondary data obtained from sources such as the internet, journals, media publications, and libraries. A
qualitative method was used for data analysis, guided by Jonas's theory of sustainable agriculture. The findings
reveal that the Nigerian government has yet to adopt renewable energy as a dependable resource for agricultural
activities. Additionally, the elite class in Nigeria and globally are identified as key opponents of climate change
initiatives and renewable energy policies aimed at phasing out fossil fuels. Based on these findings, the study recommends that the Nigerian government move beyond geopolitical constraints and enact effective legislation to prioritize renewable energy as the primary source for ensuring food security
Google Health’s Chief Clinical Officer Talks About Incorporating AI in Health Care
Authors: Voelker Rebecca
Published: September 2023

This Medical News article is an interview with Michael Howell, MD, MPH, about applications of large language models in medicine.
Co‐designing a toolkit for evidence‐based decision making in conservation: Processes and lessons
Authors: Smith Rebecca K. , Morgan William H. , Al‐Fulaij Nida , Amano Tatsuya , Bowkett Andrew E. , Christie Alec , Downey Harriet , Frick Winifred F. , O'Brien David , Ockendon Nancy , Oppel Steffen , Petrovan Silviu O. , Righton David , Tinsley‐Marshall Paul , Worthington Thomas A. , Sutherland William J.
Published: September 2023

Improving the effectiveness of conservation practice requires better use of evidence.

Since 2004, researchers from the Conservation Evidence group (University of Cambridge) have engaged with over 1100 named practitioners, policymakers, funders and other academics from across the world to identify needs and develop a range of principles, tools and resources to embed evidence in decision making. The goal of this engagement (the Conservation Evidence Programme) was to deliver improved conservation practice leading to benefits for nature and society. Together, we developed a theory of change with five key strategies for delivering change, alongside a freely available Evidence Toolkit to support decision makers in achieving that change.

The authors describe the toolkit, a collection of freely available tools and resources developed by the collaborative programme, and how co‐design, employing different levels of partner engagement, enabled its development.

Reflecting on our experiences highlighted a number of insights and recommendations, including the need to identify where deep engagement is a necessary condition for success; the importance of collective agreement of the roles of different partners; the need to consider how to facilitate uptake of new tools or practices, particularly where that requires changes to organisational practices or culture; and the importance of establishing processes/channels for ongoing engagement with stakeholders, with a willingness to be flexible and open to incorporating new suggestions and perspectives as needed.

The Conservation Evidence Programme has enabled practitioners, funders and policymakers to become part of a network of forward‐thinking organisations that is working collaboratively to help drive more effective conservation practice through improved evidence use.