bluuebunny/crossref_metadata_2025 huggingface dataset:
About a Method of the Estimation of the Recreational and Health Value of a Protected Area
Authors: Mazurkiewicz Ludwik , Pacelt Justyna
Published: February 2016

Introduction.
Recreation is very popular in protected areas where the number of visitors is increasing from year to year. They are attracted by benefits provided by natural resources in the form of favorable conditions to spend time for leisure. These benefits have a specified value which is known as a recreational one. In this paper a method is presented how to measure it.

Material and methods.
The method is an extension of an approach known as the travel cost method. The extension consists in taking additional assumptions into account like needs that drive people to recreate in protected areas and as a result the recreational and health value of the area is estimated more precisely. The calculation was realized on data collected by a survey based on an interview questionnaire among 60 respondents in the Kampinoski National Park in the second half of July 2014.

Results.
The recreational and health value estimated on the results obtained from 60 respondents amounted to 235 837 PLN and 165 194 PLN respectively. The article presents also more detailed calculations of the selected surveys.

Conclusions.
The factors which contribute in a decisive way into the area recreational and health value are the number of visits, the share of a health motive and the length of stay. There are also other factors of lesser contribution into the value like: the time of getting the area, the cost of its reaching and the sum respondents declared to pay for the area protection.
Antiproliferative effects of triterpenoidal derivatives, obtained from the marine sponge Siphonochalina sp., on human hepatic and colorectal cancer cells
Authors: Abdel-Lateff Ahmed , Al-Abd Ahmed M. , Alahdal Abdulrahman M. , Alarif Walied M. , Ayyad Seif-Eldin N. , Al-Lihaibi Sultan S. , Hegazy Mohamed E. , Al Mohammadi Ameen , Abdelghany Tamer M. , Abdel-Naim Ashraf B. , Moustafa Mohamed A.A. , Banjer Zainy M. , Azhar Ahmad S.
Published: February 2016

Three triterpenoidal derivatives [Sipholenol A (1), sipholenol L (2) and sipholenone A (3)] were isolated from the Red Sea sponge Siphonochalina sp. The structures were determined based on spectroscopic measurements (NMR, UV, IR and MS). The isolated compounds were evaluated for their cytotoxic activity against three cancer cell lines; HepG2, Caco-2 and HT-29. Moreover, the effects of these metabolites on cell cycle progression as well as cell cycle regulating proteins were assessed. Compounds 1, 2 and 3 showed moderate activity against HepG2 cells with IC50 values of 17.18 ± 1.18, 24.01 ± 0.59 and 35.06 ± 1.10 μM, respectively. Compounds 1 and 2 exerted a considerable antiproliferative effect with IC50 values of 4.80 ± 0.18 and 26.64 ± 0.30 μM, respectively, against Caco-2 cells. Finally, 1 and 2 exhibited antiproliferative activity against colorectal cancer cells (HT-29) with IC50 values of 24.65 ± 0.80 and 4.48 ± 0.1 μM, respectively. Cell cycle analysis indicated that these compounds induced cell cycle arrest particularly in G0/G1 and S phases. Furthermore, the triterpenoids increased the expression of cyclin-B1, cyclin-D1 and cleaved caspase-3, as determined by immunofluorescence, indicating an important role of apoptosis in cell death induced by these compounds.
The V̇o 2 Kinetics of Maximal and Supramaximal Running Exercises in Sprinters and Middle-Distance Runners
Authors: do Nascimento Salvador Paulo C. , Dal Pupo Juliano , De Lucas Ricardo D. , de Aguiar Rafael A. , Arins Francimara B. , Guglielmo Luiz G.A.
Published: February 2016

do Nascimento Salvador, PC, Dal Pupo, J, De Lucas, RD, de Aguiar, RA, Arins, FB, and Guglielmo, LGA. The V̇o
2 kinetics of maximal and supramaximal running exercises in sprinters and middle-distance runners. J Strength Cond Res 30(10): 2857–2863, 2016—The aim of this study was to compare the V̇o
2 kinetics parameters during maximal and supramaximal running exercises in sprinters (SPR) and middle-distance runners (MDR). Twelve SPR (age 20.6 ± 3.4 years; and body mass 74.9 ± 6.2 kg) and 10 MDR (age 17.6 ± 1.4 years; and body mass 70.1 ± 11.8 kg) performed, on different days, a maximal incremental running test for determination of the velocity at maximum oxygen uptake (vV̇o
2max) and 2 constant-speed tests for analysis of V̇o
2 kinetics at 100 and 120% of vV̇o
2max. The MDR presented significantly higher values for the critical speed (18.0 ± 1.0 vs. 14.2 ± 1.0 km·h−1), vV̇o
2max (19.4 ± 0.7 vs. 17.2 ± 0.8 km·h−1), and time to exhaustion at 100% (437 ± 53 vs. 366 ± 49 seconds) than the SPR (p ≤ 0.05). However, the SPR demonstrated greater values for the anaerobic distance capacity (281.3 ± 66.1 vs. 208.0 ± 43.4 m). Although the mean response time and the time to attain the V̇o
2max of the V̇o
2 kinetics was higher in the maximal than supramaximal running speed (p ≤ 0.05), no difference was found in these parameters as well for V̇o
2 slow component (p > 0.05) between the groups. This study showed that different aerobic and anaerobic characteristics in MDR and SPR did not affect the V̇o
2 kinetics in maximal and supramaximal intensities within the severe-intensity domain. From a practical perspective, parameters of V̇o
2 response may provide helpful information for training control as the duration of stimulus close to V̇o
2max.
External Responsiveness and Intrasession Reliability of the Rope-Climbing Test
Authors: Dhahbi Wissem , Chamari Karim , Chèze Laurence , Behm David G. , Chaouachi Anis
Published: February 2016

Dhahbi, W, Chamari, K, Chèze, L, Behm, DG, and Chaouachi, A. External responsiveness and intrasession reliability of the rope-climbing test. J Strength Cond Res 30(10): 2952–2958, 2016—Although the rope-climbing test (RCT) has been validated for upper-body power assessment of Commando soldiers, the external responsiveness and intrasession reliability of the RCT have not been reported. To examine RCT external responsiveness and intrasession reliability, this study consisted of 2 separate phases. Forty male soldiers belonging to the special units of the National Guard, selected on the basis of their training and specialty operations levels, participated in the first phase of the study to identify the discriminant ability of RCT. This group was then divided into anti-terrorism Commandos (21 soldiers) and Intervention-Brigade (19 soldiers). Only the anti-terrorism Commandos participated in the intrasession reliability study. The Commandos were significantly better than the Intervention-Brigade soldiers on execution time (ET), absolute power output (APO), and relative power output (RPO; p < 0.001). The areas under the receiver operator characteristics curves were all higher than 0.70: 0.91, 0.85, and 0.90 for ET, APO, and RPO, respectively. The RCT provided good external responsiveness; thus, RCT was considered to indicate “good” discriminative ability. No significant difference was found between groups in posttest rating of perceived exertion. The intrasession reliability coefficients were excellent for ET, APO, and RPO (intraclass correlation coefficient [3,1] > 0.90). The standard errors of measurement values for the ET, APO, and RPO were all less than 5% (range: 1.29–1.47%). The main findings of this study suggest that RCT is a tool with both high sensitivity and intrasession reliability, allowing the consistent detection of differences in upper-limb power performance between the 2 military groups of different operational capacity levels.
Effects of Short-Interval and Long-Interval Swimming Protocols on Performance, Aerobic Adaptations, and Technical Parameters: A Training Study
Authors: Dalamitros Athanasios A. , Zafeiridis Andreas S. , Toubekis Argyris G. , Tsalis George A. , Pelarigo Jailton G. , Manou Vasiliki , Kellis Spiridon
Published: February 2016

Dalamitros, AA, Zafeiridis, AS, Toubekis, AG, Tsalis, GA, Pelarigo, JG, Manou, V, and Kellis, S. Effects of short-interval and long-interval swimming protocols on performance, aerobic adaptations, and technical parameters: A training study. J Strength Cond Res 30(10): 2871–2879, 2016—This study compared 2-interval swimming training programs of different work interval durations, matched for total distance and exercise intensity, on swimming performance, aerobic adaptations, and technical parameters. Twenty-four former swimmers were equally divided to short-interval training group (INT50, 12–16 × 50 m with 15 seconds rest), long-interval training group (INT100, 6–8 × 100 m with 30 seconds rest), and a control group (CON). The 2 experimental groups followed the specified swimming training program for 8 weeks. Before and after training, swimming performance, technical parameters, and indices of aerobic adaptations were assessed. ΙΝΤ50 and ΙΝΤ100 improved swimming performance in 100 and 400-m tests and the maximal aerobic speed (p ≤ 0.05); the performance in the 50-m swim did not change. Posttraining V̇o
2max values were higher compared with pretraining values in both training groups (p ≤ 0.05), whereas peak aerobic power output increased only in INT100 (p ≤ 0.05). The 1-minute heart rate and blood lactate recovery values decreased after training in both groups (p < 0.01). Stroke length increased in 100 and 400-m swimming tests after training in both groups (p ≤ 0.05); no changes were observed in stroke rate after training. Comparisons between groups on posttraining mean values, after adjusting for pretraining values, revealed no significant differences between ΙΝΤ50 and ΙΝΤ100 for all variables; however, all measures were improved vs. the respective values in the CON (p < 0.001–0.05). In conclusion, when matched for distance and exercise intensity, the short-interval (50 m) and long-interval (100 m) protocols confer analogous improvements in swimming performance, in stroke cycle parameters, and in indices of aerobic adaptations after 8 weeks of training.
Sudden cardiac arrest and coexisting mitral valve prolapse: a case report and literature review
Authors: Ahmed Mohamed , Roshdy Ashraf , Sharma Rajan , Fletcher Nick
Published: February 2016

The aetiology of sudden cardiac arrest can often be identified to underlying cardiac pathology. Mitral valve prolapse is a relatively common valvular pathology with symptoms manifesting with increasing severity of mitral regurgitation (MR). It is unusual for severe MR to be present without symptoms, and there is growing evidence that this subset of patients may be at increased risk of sudden cardiac arrest or death. The difficulty lies in identifying those patients at risk and applying measures that are appropriate to halting progression to cardiac arrest. This article examines the association of mitral valve prolapse with cardiac arrests, the underlying pathophysiological process and the strategies for identifying those at risk.
About the aspects and roles of phrasemes in Kosztolányi’s Skylark (1924)
Authors: Bucsics Katalin
Published: February 2016

In this essay I examine the ways in which language functions both as a means of preserving the past and as a marker of change by examining the significance of phrasemes in the novel Pacsirta (Skylark) by Hungarian author Dezső Kosztolányi. In part by examining the ways in which the English and German translators of the novel dealt with the complexities posed by the historically and culturally embedded nature of language, I explore the complex and at times contradictory functions of language in the novel. Kosztolányi’s use of phrasemes in Pacsirta, I argue, exemplifies several of his theoretical ideas about language itself and the roles of language in the mediation of the past.
Budapest’s large prefab housing estates: Urban values of yesterday, today and tomorrow
Authors: Benkő Melinda
Published: February 2016

In Budapest, one third of the population lives in large prefabricated housing estates. Therefore, this Modern heritage of the Communist period is one of the key issues of sustainable urban development. The majority of scientific studies on mass housing focus on economic and social aspects, so this research intends to approach the subject from the built-up environment. Taking the people’s needs and Budapest’s specific situation in relation to the challenges of sustainability as a starting point, the paper attempts to use the back-casting method based on social, economic and environmental trends. Defining a theoretically desirable future for this dominant type of urban housing, the analysis works backwards to understand their principal historic turning points. What are the values of large prefabricated housing estates? What were they, and what could they be? How can this modern and open urban form be sustained? What elements of the existing built environment will disappear, and what can be adapted in the transition process? By introducing three different scales — city, neighborhood and building, along with their subcategories – it is possible to recognize the effects of changing socio-economic conditions upon the built context and indicate problem-oriented, locally-minded interventions.
Annotated checklist of Echinoderms from Araçá Bay, Southeastern Brazil
Authors: Alitto Renata Aparecida dos Santos , Bueno Maristela De Lima , Di Domenico Maikon , Borges Michela
Published: February 2016

We present a species list of echinoderms from Araçá Bay, state of São Paulo. Altogether, 863 specimens belonging to 25 species, 19 genera, and 13 families were exhaustively collected during three years in consolidated and non-consolidated substrate. Ophiuroidea was the most representative taxon with 16 species, follow by Asteroidea with four species, Echinoidea with three, and Holothuroidea with two species. The brittle stars Amphiura kinbergi and Ophiothela cf. mirabilis are new records for Araçá Bay. We confirm that Araçá Bay is one of the best known area of echinoderm diversity in Brazil considering that the perimeter (3 km) of the bay corresponds to only 0.03% of the Brazilian coastline (8500 km). This work complements the knowledge of Araçá Bay biodiversity and supports future interventions, management and maintaining the diversity of this wonderful group of marine animals.
State and Local Pension Funding in the Enhanced Financial Accounts
Authors: Hoops Matthew , Smith Paul , Stefanescu Irina
Published: February 2016

In this Note we describe new state-level data on the funding status of state and local government defined-benefit pension plans, which is part of the Enhanced Financial Accounts (EFA) initiative.
To Cut or Not to Cut? On the Impact of Corporate Taxes on Employment and Income
Authors: Ljungqvist Alexander , Smolyansky Michael
Published: February 2016

Do corporate tax increases destroy jobs? And do corporate tax cuts boost employment? Answering these questions has proved empirically challenging. We propose an identification strategy that exploits variation in corporate income tax rates across U.S. states. Comparing contiguous counties straddling state borders over the period 1970 to 2010, we find that increases in corporate tax rates lead to significant reductions in employment and income. We find little evidence that corporate tax cuts boost economic activity, unless implemented during recessions when they lead to significant increases in employment and income. Our spatial-discontinuity approach permits a causal interpretation of these findings by both establishing a plausible counterfactual and overcoming biases resulting from the fact that tax changes are often prompted by changes in economic conditions.
Clinical education of occupational therapy students: Reluctant clinical educators
Authors: De Witt Patricia , Rothberg Alan , Bruce Judith
Published: February 2016

Clinical education is essential to the development of clinical and professional competencies in occupational therapy students during the mandated 1000 hours of clinical practice. Students' concerns about the quality of their clinical education were raised during a routine HPCSA accreditation visit. These concerns resulted in a qualitative study which used hermeneutic phenomenology as the strategy to explore, examine and understand the 'lived experiences' of clinical education within the context of occupational therapy practice by those who provide it and who receive it. Focus groups were used to collect the data. The purpose of the focus groups was for the participants to discuss and reflect on their experiences and to identify the factors that framed those experiences and perceptions. The three groups of eight participants from each of the following: the final year students (n=32), the on-site clinical educators who had supervised final year students (n=43) and from the university clinical educators (n=12), were invited to participate. Data from the focus groups were analysed within and across the focus groups using open and then axial coding. Three themes emerged. This paper only reports on the code: Reluctant Clinical Educators within Theme 2: Challenges to quality. Reluctant Clinical educators were highlighted in each focus group and the impact of this reluctance on clinical education is described. Key words: quality of clinical education, poor role models, time, students as learners
An action research approach to profile an occupational therapy vocational rehabilitation service in public health care
Authors: van Biljon Hester , Casteleijn Daleen , Sanetta H.J , Rabothata Simon
Published: February 2016

The need for occupational therapists to profile their vocational rehabilitation services, initiated an action research project, within a PhD study. The PhD study was aimed at transforming vocational rehabilitation services in occupational therapy departments in Gauteng public healthcare through action research. The aim of the project was to develop a tool that would allow occupational therapists doing vocational rehabilitation, to systematically and comprehensively profile their services. The profile tool could be used for practice reflection, research, to assist with planning, policy making and/or quality management. It will be used in the final phase of the PhD study to allow for critical reflection on vocational rehabilitation practice transformation in Gauteng public healthcare. The profile tool was designed and developed during action research cycles in public healthcare vocational rehabilitation units. It was refined through further action research cycles with occupational therapists that offer vocational rehabilitation services in Gauteng's public healthcare. The service profiles generated from these cycles were presented for participant validation. The final profile tool was sent for critical appraisal to a panel of experts acting as 'critical friends'. The processes of designing, developing, refining, validating and disseminating the tool are presented in this article as a contribution to the practice of vocational rehabilitation and to conclude the dissemination outcome of action research. Key words: occupational therapy, vocational rehabilitation services, public healthcare, action research, profile tool
Advantages of immunohistochemistry in the diagnosis of chronic endometritis
Authors: Kolmyk Vera Aleksandrovna , Nasyrov Ruslan Abdullaevich , Kutusheva Galiya Fettyakhovna
Published: February 2016

Currently in Russia there is a high frequency of infertile marriages and spontaneous abortions. One of the main causes of fertility for women is endometrial pathology. Structural and functional deficiency of the endometrium caused by pathological inflammatory processes, naturally leads to disruption of implantation and clinically infertility and prenatal losses. Search for solutions to the treatment of endometrial pathology extremely relevant for the prevention of reproductive health of society. The main causes of endometrial pathology is inadequate hormonal regulation, acute and chronic inflammation (endometritis). For chronic endometritis is often characterized by a long asymptomatic and complexity of initial diagnosis. A special place in the course of chronic endometritis belongs herpes infection. Its prevalence among young population is high enough. Herpes infections can affect almost all organs and systems of the host. Diagnostic approaches to verification of chronic endometritis constantly adapting over the past decades. Today, the diagnosis is based on a comprehensive assessment of a number of clinical, morphological, instrumental data. Particular attention is paid to the verification of chronic endometritis immunohistochemical study of the endometrium. This method allows not only to identify the type of infectious agent, but also to establish a process phase that has a significant role in determining treatment strategy. Special role in identifying immunohistochemical viral etiology of chronic endometritis, because this method can reliably detect the presence of antigens to different viral agents.
Management of patients with abnormal uterine bleeding puberty in the outpatient setting (experience MCDC “Yuventa”)
Authors: Gogotadze Irina Nikolaevna , Krotin Pavel Naumovich , Kozhukhovskaya Tat’yana Yur’yevna , Bogatyreva Elena Magometovna
Published: February 2016

Questions of the effectiveness of therapy of abnormal uterine bleeding puberty, prevention of recurrence and restore of normal menstrual and fertility are extremely important in the future. Diagnosis of abnormal uterine bleeding puberty often is an absolute indication for hospitalization. However, the experience Saint Petersburg Municipal consultive and diagnostic center “Juventa” patients can receive medical treatment in a day hospital with good clinical effect, if they haven’t anemia and heavy bleeding. Аccording to Juventa clinic, dysfunctional uterine bleedings of the pubertal period iconsist 4 % in the structure of the gynaecological diseases among the young girls. 75-89 % of young patients with bleedings do not require hospitalization with 24 hour observation and can get medical care in the outpatient settings with good clinical effect. In 2/3 of patients could receive the hemostatic effect when using a non-hormonal therapy. In 1/3 of patients require hormone therapy. All of the patients need further medical supervision and therapy for prevention of recurrent bleeding. The effectiveness of conservative hemostatic therapy conducted in a day hospital was 97.8 %. Important conditions for a good clinical effect were: patient selection, which can be performed outpatient treatment, the use of complex therapy, dynamic assessment of the effectiveness of the therapy, timely correction of the treatment regimen with the addition of hormone hemostatic therapy.
Supratentorial Сerebral hemorrhage: Pathophysiologic Criteria and Tactics of Treatment
Authors: Spirin Andrey Leontievich , Trashkov Aleksandr Petrovich , Tsygan Nikolay Vasil’yevich , Vasiliev Andrei Glebovich , Artemenko Margarita Radievna , Pechatnikova Valeriya Antonovna
Published: February 2016

Hemorrhagic stroke (HS) constitutes 20 % of acute disorders of cerebral circulation. The incidence of HS in different regions varies between 10 and 35 per 100 thousand population. In spite of modern breakthroughs in neurosurgery and neurology cerebral hemorrhages are characteristic of high lethality and invalidization. Lethality level depends on the size of the hematoma. The lethal outcome is more probable in case of hematoma size over 100 cubic centimeters. The survival rate in patients with larger hematomas may increase provided the conventional surgical treatment is as early as possible before the development of pronounces dislocational manifestations. Hematomas over 80 cubic centimeters case death irrespective of the treatment method due to a combination of large size of hematoma and fast development of intracranial hypertension and dislocation syndrome. Lobar hematomas develop in a more benignant manner while mixed ones may be classified prognostically unfavorable: the lethality in this group is considerably higher than in in other hematomas. The lethality and gravity of clinical manifestations in case of medial hematomas is associated with haigh frequency of intraventricular hemorrhages. Considerable variability of hypertension hematomas’ treatment results testifies to an absence of a common approach to surgical treatment. Surgical treatment may demonstrate its convincing advantages only in case of strict approach to selection of patients for surgery which requires an integral scale for the assessment of the patients’ state. Taking into consideration the high demand for surgical treatment of cerebral hematomas in Russian Federation (about 11 000 operations per year) organization measures are necessary to create additional neurosurgical departments for emergency surgical aid for HS patients.
To the problem of the organization of independent study of students in medical school (on the example of the network project)
Authors: Zinkevich Elena Romanovna
Published: February 2016

In article the problem of the organization of independent work of students is considered. From the basic pedagogical point of view, independent study is such type of educational activity at which a certain level of independence of a student in all its structural components is supposed - from statement of the purpose to the control, the self-control and correction which carries out gradual transition from performance of the elementary types of work to more difficult ones, having exploratory nature. From the point of view of the author, independent study of students is a development tool of their cognitive interests and abilities, formations of special abilities for continuous self-education. In the article such conditions of the organization of independent study of students are described: mastery of the methods of organization and reflection of own educational cognitive activity; existence of necessary educational and methodical and special literature; scientific-methodical and information-methodical support of this type of educational activity, etc. The organization of independent work of students is possible on the basis of design training. Design training assumes creation of a process of assimilation of knowledge in the logic of an integrated approach to educational cognitive activity of students which has to make for them personal sense. The author considers the network educational project as one of the ways of the organization of independent work of students. In this connection, functions of the network educational project, conditions of its organization and the didactic requirements imposed to its organization are described. The option of the organization of independent work of students within the network educational project is offered on the example of the educational discipline “Pedagogical psychology”.
Contribution of N. P. Kravkov to development of the general, aged, evolutionary and clinical pharmacology (in memoriam to 150 years from the birth)
Authors: Shabanov Petr Dmitrievich
Published: February 2016

In the paper, the life and scientific achievements of Nikolai Pavlovich Kravkov (1865-1924), a founder of the Russian pharmacology, head of the Department of Pharmacology, Military Medical Academy, St. Petersburg, were described. N. P. Kravkov carried out significant investigations in pharmacology of gas metabolism, drug toxicology, aged and evolutionary pharmacology, clinical pharmacology (discovery of intravenous and combined narcosis). The main achievement of N. P. Kravkov became the cycle of investigations on isolated organs (ear, heart, lung, spleen, pancreatic gland, thyroid gland, adrenal gland, uterus of the mammalians, head and gills of pike, human fingers, heart and spleen). In these investigations, the rhythmic oscillation of the vascular tonus was proved, the theory of phasic action of pharmacological drugs on tissues, presentations on sensitiveness limits of living protoplasma, possibilities of animation of mummified tissues were postulated. N. P. Kravkov created a large scientific school (S. V. Anichkov, M. I. Gramenitskii, G. L. Shkavera, M. N. Nikolaev, A. I. Kuznetsov, B. S. Sentyurin, V. V. Zakusov, V. A. Valdman). For 25 years (1899-1924) N. P. Kravkov headed the Department of Pharmacology of Military Medical Academy. Commission for awarding the prize V. I. Lenin for scientific work which included the most prominent scientists of our country (O. J. Schmidt was Chairman), A. N. Bach, P. P. Lazarev, S. G. Navashin and M. N. Pokrovsky decided to award the prize to N. P. Kravkov for proceedings in 1926 year.
Investigation of LTF and GDF-9 gene polymorphism and in mammals (Bos Taurus L) by PCR-RFLP analysis for pharmacogenetics
Authors: Proshin Sergei Nikolaevich , Usenbekov Essengali Serikovich , Shakibaev Erden Bakhitbekovich , Bimenova Zhanat Zholshybaikyzy , Zhumakhanova Raisa Mukhamediyarovna , Glushakov Ruslan Ivanovich , Dement’eva Natal’ya Viktorovna
Published: February 2016

It has been established the close relationship between gene polymorphism of lactoferrin (LTF) with an incidence of mastitis and somatic cell counts in milk of mammals. Lactoferrin gene products are associated with resistance to several diseases, and particularly for mastitis. Lactoferrin (LTF) is a multifunctional small glycoprotein of milk. Its main function is to protect the breast. It is considered that genetic variants of DNA lactoferrin could be used as a marker for the prediction of somatic cells in milk and mastitis incidence. Allele A of LTF gene is associated with the incidence of mastitis in mammals such as cows. It has also been established that the polymorphism of BMP15 and GDF9 genes of sheep influence the number and rate of ovulation. Thus the alleles of Bone morpho-genetic protein (BMR15) gene influence the process of folliculogenesis in sheep. Sheep heterozygous on this locus ovulate two or three oocytes. The authors of this study recommend the use of polymorphism BMP15 gene as DNA markers to increase fertility in sheep. It is well known that products of GDF9 gene control the process of growth and development of follicles in cows. Polymorphisms of the gene is well studied in medicine. Women who have a mutation in the coding region of the gene GDF9 found signs of premature ovarian failure. The study of lactoferrin gene polymorphism has theoretical and practical importance since there is a positive correlation between the content in milk of somatic cells and genetic variants of lactoferrin. Thus, the authors suggest the use of GDF9 gene polymorphism in cows as a DNA marker for the prediction of reproductive function in mammals. The aim: to study DNA polymorphism of genes LTF, GDF9 and identified animals (Bos Taurus L) with the desired genotype for the studied loci to build model for searching new pharmacological agents.
Minilaparoskopy (Mini Site) in surgical treatment of childbearing age patients
Authors: Gurkin Juriy Aleksandrovich , Plekhanov Andrei Nikolaevich
Published: February 2016

Nowadays gynecologists try to find less traumatic and more effective variants of surgical treatment. Minilaparoscopic surgery is a resultant achievement of developments in gynecology since the beginning of the 20th century. It is a novel real-time surgical method. During the last decade the authors have accomplished 270 minilaparoscopic operations. The present paper sums up our experience in minilaparoscopic operations involving the uterus, Fallopian tubes, ovaries (salpingolysis, decortication, endometriosis sites excision, gonadectomy, etc.). The advantages of this kind of surgical operation especially promising in infantile gynecology are disclosed. Among the advantages of minilaparoscopic approach in infantile gynecology the authors emphasize the decrease of preoperational period, optimization of diagnostics during the operation, sparing techniques, reduction of post-operational complications. The aforementioned features of laparoscopic surgery suggest breakthroughs in normalizing nature of treatment in gynecology improving reproductive well-being of females and reproductive potential of girls. As a result we expect better demographic and reproductive prospects in future.
Palliative surgery in locally advanced thyroid cancer
Authors: Bagaturiya Georgy Otarovich , Romanchishen Anatoly Filippovich
Published: February 2016

The paper analyses the experience in palliative surgery in 137 patients with locally advanced forms of differentiated thyroid cancer. The paper describes the resections of the thyroid gland without the tumor tissue that germinated into the vital organs of neck or mediastinum. In some cases - the tumor was completely removed in patients with distant metastases. Such operations had to be performed in every fourth patient out of 464 patients with locally advanced carcinoma of the thyroid gland. Most of the patients undergoing palliative interventions, were elderly patients, that often had other illnesses. The need for such transactions occurred at the prospect of further treatment of patients with non-surgical methods, and serious complications of life-threatening tumors. In more than one in ten patients the palliative operation had to be completed with a temporary or permanent tracheostomy performed using the original method. The postoperative mortality rate was 4.3 % (6 cases). The causes of death were pulmonary embolism (2 patients), acute myocardial infarction (1 patient), purulent-septic complications (2 patients), acute cerebrovascular accident (1 case). The postoperative complications were: festering wounds (10 cases or 7.3 %), hypostatic pneumonia (21 patients or 15.3 %), bleeding (3 cases or 2.2 %). The 5-year survival rate after palliative surgery in patients with papillary cancer was higher compared to the group of patients with follicular carcinoma (43.0 % and 37.9 %, respectively). The same figures in patients with medullary carcinoma were significantly (p < 0.05) lower compared with those with papillary and follicular thyroid cancer and they amounted to 18.1 %. After the palliative surgery more than a third of patients survived for 5 years or more. That proves the validity of palliative interventions in this group of patients, and the relatively favorable current differentiated forms of thyroid cancer.
Modeling to close of interatrium septum defects of the heart
Authors: Lazarev Sergey Mikhaylovich , Lazareva Yelizaveta Yuryevna
Published: February 2016

Atrial septal defect (ASD) of the secundum type are the most common lesions. More than half of the century a surgeons are operating second defect of ASD of the heart. But a choice to close this defect have the empirical character. In this work the method of the modeling on computer was used. Were studied biomechanical properties of the interatrial septum in norm and with the defect, fnd the methods to close such defects: to close to the patch, sutured, endovascular close defects use device “Amplatzer septal occlude” (ASO). This models was build with accounting famous the size of the tension for every tissue structure. The models of the tension and motion were to came out. Than the results were compared. This results allowed the authors had to determinate the use of relapse of ASD after close of the defects with patchs, suture, and the device of the “ASO”. Most the tension and the motion appear in the oval pit of the septum were discovered. Was notice that the tension and the motion were decreased with increased the thickness this part of the septum. Therefore the second ASD must be close with the stuffs or devices which equal or greater than thickness the interseptum patch. In this connection the patch from any stuff are not better the method of the operation or the stuff is must be greater 1,5 than the area of the oval pit. When the defect is sutured there is great the tension and motion in the region of the suture. It is the danger of the relapse of the heart defect. When the defect is close the device of “ASO” there is small the tension and motion in the part of contact the device and interatrium septum that exclude the defect relapse.
A “calma” em dois momentos de cinema: aristotélico, “Bombita”, 4º episódio de Relatos salvajes de D. Szifrón; e não ou para-aristotélico, Céu sobre água de J. Agrippino de Paula
Authors: Assunção Teodoro Rennó
Published: February 2016

Este artigo comenta brevemente o quarto episódio, “Bombita”, do ﬁlme Relatos salvajes de Damián Szifrón (2014), e o curta-metragem Céu sobre água de José Agrippino de Paula (1978), como exemplos possíveis tanto da “calma” (praótes) tal como deﬁnida – em contraste com a “cólera” (orgé) – por Aristóteles no livro II da Retórica (“Bombita”, do ﬁlme Relatos salvajes de D. Szifrón), quanto da “calma”, pensada positivamente e não mais apenas negativamente (Céu sobre água de J. Agrippino de Paula), segundo um modelo bem diferente, portanto, daquele de Aristóteles para esta “emoção” no livro II da Retórica.
Literatura e Retórica na Institutio oratoria de Quintiliano e no Supremo Tribunal Federal brasileiro
Authors: Miotti Charlene Martins , Rezende Wagner Silveira
Published: February 2016

Este trabalho tem por objetivo apontar semelhanças entre alguns recursos argumentativos dos juízes do Supremo Tribunal Federal brasileiro e os preceitos de Quintiliano no sexto livro da Institutio oratoria quanto à manipulação das emoções do auditório e ao emprego de excertos literários em discursos forenses. Para tanto, compara-se seis citações diretas da Eneida de Virgílio, usadas pelo antigo rétor para ilustrar algumas estratégias de persuasão bem sucedidas, aos votos de cinco juízes em três hard cases recentes que atraíram muita atenção midiática: a ADI 3510 (lei de biossegurança sobre pesquisa com células- tronco), a ADI 4277 (reconhecimento da união homoafetiva) e a ADPF 54 (descriminalização do aborto em casos de nascituros diagnosticados com anencefalia). A comparação parece oportuna para demonstrar a atualidade e a circulação de um modus operandi retórico já discutido e aceito pelos antigos, mas que, modernamente, engendra certa ameaça ao mito do Direito imparcial e objetivo.
Outcome of fracture of intra articular distal femur treated with distal femur locking compression plate
Authors: Trivedi Nirav P. , Chauhan Rajdeepsinh H. , Padhiyar Darshansinh R. , Gandhi Shreyas P.
Published: February 2016

Background: Intra articular fracture of the distal femur is a composite and complex injury that poses various challenges for orthopaedic surgeon starting from management of fracture to a protracted recovery of the patient.

Methods: We have done retrospective study of 25 patients with intra articular distal femur fracture operated during the period of 2008 to 2014. NEER score is used as criteria for evaluation of patients.

Results: With use of DFLCP, anatomical reduction and rigid fixation, early mobilization and aggressive physiotherapy can be started with the use of these plates.

Conclusions: Our study shows that distal femur locking compression plate (DFLCP) is the evolving approach to treat distal femur fractures.
Long standing healed tubercular kyphosis and overlying skin infection with localized collection: an underreported complication
Authors: Dharmshaktu Ganesh S.
Published: February 2016

The sequelae of healed post-tubercular spine infection often results in ankylosed and fused vertebrae producing kyphosis of varied presentation. The natural bony ankylosis thus helps stabilization of the diseased segment while the infection heals and is the end result of a successful treatment. The complications related to the residual deformity depend on the site, magnitude and associated degree of damage during the course of disease.
Cutaneous lymphangiectasia of the vulva secondary to pulmonary tuberculosis: a case report
Authors: Arya Savita , Nyati Asha , Bunkar Motilal , Takhar Rajendra Prasad , Mirdha Saroj
Published: February 2016

Cutaneous lymphangiectasia of the genitalia represent dilatation of upper dermal lymphatic’s following damage to previously normal deep lymphatics, is an uncommon condition and only few cases have been reported following pulmonary tuberculosis. Here we are describing a case of 75 years old female patient, who came with multiple translucent papulovesicular lesions over the vulva, labia majora, minora and upper thigh from twelve year duration, with watery discharge since eight years. She had a history of pulmonary tuberculosis twenty years ago. The patient underwent punch biopsy of the lesion over the vulva and histopathological examination confirmed our diagnosis as lymphangiectasia of the vulva. She was managed conservatively with anti-tubercular drugs and got relief in watery discharge and skin lesions.
A case of cutaneous rosai-dorfman disease diagnosed by fine needle aspiration cytology
Authors: Abraham Latha K. , George Pulickal Sajeev , Poothiode Usha
Published: February 2016

A 30 year old female presented with a swelling in the back of a few weeks duration. Clinical examination revealed no other abnormalities. Fine needle aspiration cytology (FNAC) was suggestive of Rosai- Dorfman disease (RDD). The diagnosis was confirmed by biopsy and immunohistochemistry. FNA diagnosis of purely cutaneous RDD has very rarely been reported.
Jaundice in a baby with self-improving collodion ichthyosis and ALOX12B mutation- a challenging scenario
Authors: Suresh Indrajit , AS Jyotsna , Katyal Meenakshi , Balla Sruthi , Kothe Suryaprakash R. , S. Nirbheek
Published: February 2016

Autosomal recessive congenital ichthyoses are a heterogeneous group of rare cornification diseases. Genetic mutations are responsible for the condition, with some causing a relatively milder phenotype such as ‘self-improving collodion ichthyosis’. In most cases, affected babies are born with a thick parchment like membrane covering their body. These babies may have a problematic postnatal course, and are prone to complications. The authors present the report of a newborn collodion baby afflicted with ALOX12B mutation, who had a challenging post natal course. Difficulties in feeding, temperature control, hydration and electrolyte balance were encountered and required precise monitoring and formulation of an effective treatment strategy. Treatment of jaundice in the baby also presented a unique challenge, which was successfully managed.
Riesgo nutricional e inseguridad alimentaria en una población infantil del municipio de Soacha
Authors: Rodríguez M. Fabio , Acevedo F. Ana María , Calderón G. Magda Alejandra , López R. Diana Del Socorro , González R. María Paula
Published: February 2016

Este es un estudio descriptivo transversal para analizar las características nutricionales de una población de niños menores de cinco años de un hogar comunitario del Municipio de Soacha. Se aplicaron encuestas descriptivas a una muestra de 74 niños y sus respectivos cuidadores para conocer el imaginario colectivo acerca de los hábitos alimenticios y el acceso a la canasta básica de alimentos, y se analizaron los datos antropométricos de los niños. En la evaluación antropométrica, se encontró desnutrición crónica en 30,2% de la muestra y riesgo de desnutrición aguda dada por una media a -1 desviación estándar (DE) en el indicador de perímetro braquial para la edad. También se evidenció una diferencia en el concepto de alimentación sana entre los niños y sus cuidadores, además de un bajo presupuesto destinado para la canasta básica de alimentos saludables.
Intimate Partner Violence in Men Voluntarily Attending Treatment: A Study of Couple Agreement
Authors: Strandmoen John-Filip , Askeland Ingunn Rangul , Tjersland Odd-Arne , Wentzel-Larsen Tore , Heir Trond
Published: February 2016

Most studies examining couple agreement on intimate partner violence (IPV) have found low agreement on levels of violence. This study explored agreement on male-perpetrated IPV in a sample of 93 couples where the man was voluntarily seeking IPV treatment. Five different types of violence were assessed: physical, physically controlling, psychological, property, and sexual. The results were mixed. When disagreement was found, this resulted from men attending IPV treatment reporting less violence than their partners. However, only psychological violence was consistently reported differently. Reliability estimates ranged from poor to moderate. Couples reported on sexual violence with less reliability than physical or physically controlling violence when referring to a typical month last year. Measurement of different types of violence among both partners in a couple is recommended in clinical and research settings as well as thorough discussions with clients voluntarily enrolled in treatment for IPV on what constitutes violence.
“The Police Have Given Up”: An Empirical Examination of Covictims’ Beliefs About Cold Case Homicide Investigations
Authors: Stretesky Paul B. , Cope Kathryn , Shelley Tara O’Connor , Hogan Michael J. , Unnithan N. Prabha
Published: February 2016

This work examines the perception by cold case homicide covictims that police have given up trying to solve their loved one’s murder. A random sample (n= 65) of cold case homicide covictims is surveyed to determine if, and how, different forms of communication may be important in their perceptions about police. Ordered logistic regression analyses indicate that perceived importance of the information communicated, frequency of police contact, and satisfaction with communication efforts by police are inversely correlated with covictims’ perceptions that police have given up on the investigation. These inverse correlations persist despite statistical controls and have important implications for the bereavement of covictims and for crime rates.
Correlates of Problem Drinking and Drug Use in Black Sexual Assault Victims
Authors: Long LaDonna , Ullman Sarah E.
Published: February 2016

Few studies have examined factors related to problem drinking and drug use in Black sexual assault victims. Given that sexual assault and histories of trauma are associated with substance abuse in victims, research is needed to determine what factors may be related to these outcomes for Black survivors. Furthermore, child sexual abuse (CSA) is a risk factor for substance abuse, but no studies have examined correlates of substance abuse outcomes separately according to CSA history. This study examines a large diverse sample of Black sexual assault victims (N = 495) to determine the associations of demographics, trauma history, assault characteristics, and postassault psychosocial factors with problem drinking and drug use using multivariate regressions. Traumatic life events, using substances to cope and self-blame, were associated with greater problem drinking and drug use. Implications for practitioners and policymakers are discussed.
The Clinical and Radiological Examination of Acute Intimate Partner Violence Injuries: A Retrospective Analysis of an Italian Cohort of Women
Authors: Matteoli Marco , Piacentino Daria , Kotzalidis Georgios D. , Serata Daniele , Rapinesi Chiara , Angeletti Gloria , Rossi Michele , David Vincenzo , Dominicis Chiara De
Published: February 2016

Background: Intimate partner violence (IPV) is the most frequent type of violence against women. We compared clinical and radiological IPV characteristics to stranger assault (SA). Methods: We retrospectively identified 123 women with IPV from court reports and matched them to 124 SA. Clinical and radiological characteristics were evaluated by testing their sensitivity, specificity, positive and negative predictive value for IPV, and the strength of their association with IPV. Results: IPV women referred with more delay to the emergency department (ED), had more ED accesses, and showed more mismatch between reports to the triage and disclosures to the ED physician. They also displayed more head, neck, and face injuries, and new-plus-old fractures. Conclusion: The identification of specific features may help ED physicians to suspect IPV.