bluuebunny/crossref_metadata_2025 huggingface dataset:
ChemInform Abstract: Pd‐Catalyzed Arylation of Dialkylphosphites
Authors: NOVIKOVA Z. S. , DEMIK N. N. , AGARKOV A. YU. , BELETSKAYA I. P.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Asymmetric (2,3)‐Wittig Rearrangements with Chiral, Phosphorus Anion Stabilizing Groups.
Authors: DENMARK S. E. , MILLER P. C.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: 2,3‐Diphenyl‐5,6‐bismethoxycarbonyl‐1,4‐diphosphadihydropentalene.
Authors: MAERKL G. , HENNIG R. , NOETH H.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Stereoselective Synthesis of Homochiral (E)‐Vinyl Phosphonates Derived from (‐)‐Ephedrine.
Authors: TAAPKEN T. , BLECHERT S.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Photoactivatable Fluorescein Derivatives Bearing Side Chains with Varying Properties.
Authors: CORRIE J. E. T. , TRENTHAM D. R.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Isomerization of 4‐Aryl‐4‐methylhex‐5‐en‐2‐ones to 5‐Aryl‐4‐methylhex‐ 5‐en‐2‐ones by an Intramolecular Ene‐Retro Ene Reaction Sequence.
Authors: SRIKRISHNA A. , KRISHNAN K. , VENTKATESWARLU S. , KUMAR P. P.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Synthesis of (3R*,4R*)‐Luffariolide E via 1,2‐Metallate Rearrangement.
Authors: HAREAU‐VITTINI G. , KOCIENSKI P. , REID G.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Total Synthesis of (.+‐.)‐Parvifoline and (.+‐.)‐Isoparvifolinone.
Authors: VILLAGOMEZ‐IBARRA R. , ALVAREZ‐CISNEROS C. , JOSEPH‐NATHAN P.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Bromination of Camphene
Authors: TITOVA T. F. , KORCHAGINA D. V. , BARKHASH V. A.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Alkoxy Radical Induced Transannular Cyclizations of a Substituted (E)‐ 5‐Cyclodecenone Derivative: Synthesis of Bicyclo(5.3.0)decanes.
Authors: ARENCIBIA T. , PRANGE T. , SALAZAR J. , SUAREZ E.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Novel and Efficient Process to 13β‐Ethyl‐gon‐4‐ene‐3,11,17‐ trione.
Authors: LIU L.‐G. , SU X.‐D. , LI Z.‐S.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Convenient Synthesis of 5‐Oxo‐L‐pipecolic Acid Derivatives from L‐ Glutamic Acid.
Authors: KO K.‐Y. , PAK Y.‐P.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: A Protection Scheme for the Preparation of Acid Chlorides of Serine and Threonine.
Authors: XI N. , CIUFOLINI M. A.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Diels‐Alder Reactions of Isoprene and 1,3‐Butadiene with Nitroheptenes Derived from Sugars.
Authors: ROMAN E. , BANOS M. , GUTIERREZ J. I. , SERRANO J. A.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of 1,6‐Anhydro‐2,3‐di‐O‐farnesyl‐5‐O‐(((phosphonomethyl) phosphinyl)methyl)‐α‐D‐galactofuranose: A Zaragozic Acid‐ Presqualene Pyrophosphate Hybrid.
Authors: VALENTIJN A. R. P. M. , BROXTERMAN H. J. G. , VAN DER MAREL G. A. , COHEN L. H. , VAN BOOM J. H.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Expedient Conversion of Lactose into Versatile Derivatives of Lactosamine and β‐D‐Galactosyl‐(1 → 4)‐D‐mannosamine.
Authors: KAJI E. , LICHTENTHALER F. W.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: New Surfactants with Sugar‐Based Polar Heads Derived from Bile Acids: The N‐Ursocholyl‐D‐glucosamine and N‐Dehydrocholyl‐D‐glucosamine.
Authors: AZEMA J. , CHEBLI C. , BON M. , RICO‐LATTES I. , LATTES A.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Nucleophilic Opening of N‐Carboalkoxy‐2,3‐anhydro‐1‐ deoxymannojirimycin. A Useful Method for the Syntheses of 2‐, 3‐ and 2, 3‐Disubstituted 1‐Deoxynojirimycin Analogues.
Authors: KHANNA I. K. , KOSZYK F. J. , STEALEY M. A. , WEIER R. M. , JULIEN J. , MUELLER R. A. , RAO S. N. , SWENTON L. , GETMAN D. P. , DECRESCENZO G. A. , HEINTZ R. M.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Desulfation of Sulfated Carbohydrates Mediated by Silylating Reagents.
Authors: TAKANO R. , KANDA T. , HAYASHI K. , YOSHIDA K. , HARA S.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Direct Transformation of D‐Idose (I) and D‐Altrose (IV) with Potassium Cyanate into Cyclic Carbamates of Derived Glycosylamines.
Authors: KOVACS J. , PINTER I. , KOELL P.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Chemistry and Biology of the 2β‐Alkyl‐3β‐phenyl Analogues of Cocaine: Subnanomolar Affinity Ligands that Suggest a New Pharmacophore Model at the C‐2 Position.
Authors: KOZIKOWSKI A. P. , SAIAH M. K. E. , JOHNSON K. M. , BERGMANN J. S.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Short, Enantiospecific Syntheses of Indolizidines 209B and 209D, and Piclavine A from Diethyl‐L‐glutamate.
Authors: JEFFORD C. W. , SIENKIEWICZ K. , THORNTON S. R.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis, Toxicological, Pharmacological, and Bronchodilating Activity in vitro of Some Xanthineacetic Acid Derivatives
Authors: PEIKOV P. , DANCHEV N. , ZLATKOV A. , IVANOV D. , BELCHEVA N.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis of Novel 3′‐C‐(Hydroxymethyl)thymidines and Oligodeoxynucleotide Analogues Containing Compressed 3′‐C‐ Hydroxymethyl‐Linked Phosphodiester Backbones.
Authors: WENGEL J. , SVENDSEN M. L. , JOERGENSEN P. N. , NIELSEN C.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Isolation and Characterization of an Unusual Nucleoside, 1‐α‐D‐ Ribofuranosyl‐4‐pyridone‐3‐carboxamide, from the Urines of Normal Human Individuals and Leukemic Patients
Authors: CHHEDA G. B. , PATRZYC H. B. , TWOREK H. A. , DUTTA S. P.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: An Efficient Synthesis of 2‐((4‐Amino‐1,2‐dihydro‐2‐oxo‐1‐pyrimidinyl) methoxy)‐1,3‐propanediyl‐di‐L‐valinate, an Anti‐Cytomegalovirus Agent.
Authors: GHALI N. , JOHNSTON B. , BEAUCHAMP L. , NASEREE T. , SCOTT T. , FLANAGAN R. , RODRIGUEZ M.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Syntheses of Novel 3‐Substituted‐2′‐deoxy‐3‐deazauridine Nucleosides.
Authors: DEVADAS B. , ROGERS T. E. , GRAY S. H.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Ullmann Ether Reaction Involving an Alkynyl Substrate: A Convergent Route to a Combretastatin Intermediate.
Authors: BLASE F. R. , BANERJEE K.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Synthesis and Biological Evaluation of Both Enantiomers of Dynemicin A Model Compound.
Authors: NISHIKAWA T. , YOSHIKAI M. , OBI K. , KAWAI T. , UNNO R. , JOMORI T. , ISOBE M.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Total Synthesis of Swinholide A. Part 1. A Stereocontrolled Synthesis of a C19‐C32 Segment (XIV).
Authors: PATERSON I. , CUMMING J. G. , WARD R. A. , LAMBOLEY S.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: The Total Synthesis of Swinholide A. Part 3. A Stereocontrolled Synthesis of (‐)‐Pre‐Swinholide A.
Authors: PATERSON I. , WARD R. A. , SMITH J. D. , CUMMING J. G. , YEUNG K.‐S.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Metal Ion Extraction/Insertion Reactions with Todorokite‐Type Manganese Oxide in the Aqueous Phase.
Authors: FENG Q. , KANOH H. , MIYAI Y. , OOI K.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Preparation and Doping of Zinc Oxide Using Spray Pyrolysis.
Authors: DE MERCHANT J. , COCIVERA M.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Distorted Sandwich Compounds: (1)Ferrocenophanes and (2) Ruthenocenophanes
Authors: HERBERHOLD M.
Published: August 2010

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Investigation of high pressure permeation behaviour of single gases through microporous ceramic membranes Part 1. Measurement method and influence of adsorption on permeation
Authors: Wall Y. , Mudimu O. A. , Braun G. , Brunner G.
Published: August 2010

Zwei asymmetrische keramische Membranen wurden getestet: eine mesoporöse ZrO2‐Membran mit einem Porendurchmesser von 3 nm und eine mikroporöse TiO2‐Membran mit 0,9 nm Porendurchmesser. Der Permeatfluss reiner Gase bei 293 – 373 K und 1 – 10 MPa wurde mittels statischer und dynamischer Messmethoden gemessen, wobei beide Methoden übereinstimmende Ergebnisse lieferten.
Aufbau eines Generators zur dynamisch‐gravimetrischen Herstellung von Atemalkohol‐Kalibriergasgemischen
Authors: Pratzler S. , Knopf D. , Ulbig P. , Scholl S.
Published: August 2010

Wassergesättigte Atemalkohol‐Kalibriergasgemische werden häufig nach dem Sättigungsverfahren hergestellt. Die Ethanolkonzentration im Gasstrom wird dabei über empirische Verteilungskoeffizienten berechnet, deren Werte jedoch in der Literatur eine deutliche Varianz zeigen. In diesem Beitrag wird der Aufbau eines Generators beschrieben, mit dem Kalibriergasgemische für die Atemalkoholmesstechnik erstmals auf dynamisch‐gravimetrische Weise, unabhängig von empirischen Verteilungskoeffizienten hergestellt werden. Die Unsicherheit der Ethanolkonzentration wird anhand des GUM (Guide to the Expression of Uncertainty in Measurement) berechnet. Die Gasgemische des dynamisch‐gravimetrischen Generators werden mit denen des Sättigungsverfahrens verglichen. Aus den Ergebnissen des Vergleichs können neue Verteilungskoeffizienten für das Stoffsystem Ethanol‐Wasser‐Luft berechnet werden.
Biodegradation of Petroleum Hydrocarbons by Pseudomonas putida Strain MHF 7109
Authors: Singh Dipty , Fulekar Madhusudan H.
Published: August 2010

Pseudomonas putida MHF 7109 has been isolated and identified from cow dung microbial consortium for biodegradation of selected petroleum hydrocarbon compounds – benzene, toluene, and o‐xylene (BTX). Each compound was applied separately at concentrations of 50, 100, 250, and 500 mg L−1 in minimal salt medium to evaluate degradation activity of the identified microbial strain. The results indicated that the strain used has high potential to degrade BTX at a concentration of 50 mg L−1 within a period of 48, 96, and 168 h, respectively; whereas the concentration of 100 mg L−1 of benzene and toluene was found to be completely degraded within 120 and 168 h, respectively. Sixty‐two percent of o‐xylene were degraded within 168 h at the 100 mg L−1 concentration level. The maximum degradation rates for BTX were 1.35, 1.04, and 0.51 mg L−1 h−1, respectively. At higher concentrations (250 and 500 mg L−1) BTX inhibited the activity of microorganisms. The mass spectrometry analysis identified the intermediates as catechol, 2‐hydroxymuconic semialdehyde, 3‐methylcatechol, cis‐2‐hydroxypenta‐2,4‐dienoate, 2‐methylbenzyl alcohol, and 1,2‐dihydroxy‐6‐methylcyclohexa‐3,5‐dienecarboxylate, for BTX, respectively. P. putida MHF 7109 has been found to have high potential for biodegradation of volatile petroleum hydrocarbons.
Proposed Adsorption–Diffusion Model for Characterizing Chromium(VI) Removal Using Dried Water Hyacinth Roots
Authors: Sarkar Debasish , Das Sudip Kumar , Mukherjee Paramartha , Bandyopadhyay Amitava
Published: August 2010

Experiments have been carried out to characterize the adsorption of chromium(VI) in the aqueous phase onto dried roots of water hyacinth. Results revealed a very high degree of removal efficiency (∼100%). Theoretical analyzes are also made for describing the sorption and diffusion processes. The effective pore diffusivity of chromium(VI) in the water hyacinth roots is determined by a suitable global optimization technique. The depth of penetration, on the other hand, has been estimated for various initial concentrations of chromium(VI). Theoretically predicted concentration profiles are in excellent agreement with the experimental values.
Radiation‐induced sarcoma in patients with nasopharyngeal carcinoma
Authors: Xi Mian , Liu Meng‐Zhong , Wang Hai‐Xia , Cai Ling , Zhang Li , Xie Chun‐Fang , Li Qiao‐Qiao
Published: August 2010

BACKGROUND:

The increasing incidence of radiation‐induced sarcoma (RIS) has become a significant problem that can limit long‐term survival. The objective of the current study was to analyze the clinicopathologic characteristics, treatment outcomes, and prognostic factors of RIS after radiotherapy for nasopharyngeal carcinoma (NPC).

METHODS:

Institutional electronic medical records of patients with NPC who received definitive radiotherapy between February 1964 and 2003 were reviewed. Fifty‐three patients who developed RIS and fulfilled the study criteria were included.

RESULTS:

The median follow‐up after a diagnosis of RIS was 15.5 months (range, 0.4‐90.3 months), and the median latency between radiotherapy for NPC and an RIS diagnosis was 9.3 years (range, 3.2‐26.6 years). Fibrosarcoma was the most frequent histologic type observed, followed by osteosarcoma, and malignant fibrous histiocytoma. The 3‐year overall survival (OS) rate for 49 patients who received treatment was 32.4%, and the median survival was 21.2 months (95% confidence interval, 8.7‐33.8 months). The median OS was 41.3 months, 8.4 months, and 11 months for the complete resection group, the incomplete resection group, and the chemotherapy group, respectively (P<.0001). The only independent predictive factor that was associated with better OS was complete surgical resection.

CONCLUSIONS:

This retrospective study confirmed the rarity and poor prognosis of RIS in patients with NPC. Complete surgical resection was a significant prognostic factor for survival. The authors concluded that long‐term follow‐up is necessary for the early detection of RIS in patients with NPC. Cancer 2010. © 2010 American Cancer Society.
Enhanced Emission of Silver Nanoclusters Through Quantitative Phase Transfer
Authors: Díez Isabel , Jiang Hua , Ras Robin H. A.
Published: August 2010

Silver nanoclusters composed of only a few metal atoms present appealing properties such as fluorescence. We have previously reported on aqueous solutions of this fluorophore using poly(methacrylic acid) as scaffold and their sensing properties. Here we report on the preparation of organic solutions of fluorescent silver nanoclusters by quantitative transfer from aqueous solution to an immiscible organic solvent. The fluorescent silver nanoclusters in the organic phase present enhanced emission properties and increased purity, which may expand the range of applications of this promising fluorophore.
In Situ Infrared Study of the Role of PEG in Stabilizing Silica‐Supported Amines for CO2 Capture
Authors: Tanthana Jak , Chuang Steven S. C.
Published: August 2010

The CO2 capture capacity, adsorption mechanism, and degradation characteristics of two sorbents, silica‐supported tetraethylenepentamine (TEPA/SiO2) and polyethylene‐glycol‐modified TEPA/SiO2 (PEG/TEPA/SiO2), are studied by diffuse reflectance infrared Fourier transform spectroscopy and mass spectrometry. The CO2 capture capacities of TEPA/SiO2 and PEG/TEPA/SiO2 are determined to be 2087 and 1110 μmol CO2 g−1 sorbent, respectively. Both sorbents adsorb CO2 as hydrogen‐bonding species, NH2O, and carbamate/carboxylate species. The CO2 adsorption half‐time increases with the number of CO2 capture cycles. Infrared results suggest that the increased adsorption half‐time is a result of diffusion limitation, caused by accumulation of TEPA and PEG species on the surface of the sorbent particles. The degradation of TEPA/SiO2 is found to correlate with the accumulation of carboxylate/carbamic species. The addition of PEG decreases the degradation rate of the sorbent and slows down the formation of carboxylate species. These carboxylate species can block CO2 capture on amine (NH2/NH) sites. The stabilizing role of PEG on TEPA/SiO2 can be attributed to hydrogen‐bonding between TEPA (NH2/NH)and PEG (OH).
Direct Synthesis of Ethanol from Dimethyl Ether and Syngas over Combined H‐Mordenite and Cu/ZnO Catalysts
Authors: Li Xingang , San Xiaoguang , Zhang Yi , Ichii Takashi , Meng Ming , Tan Yisheng , Tsubaki Noritatsu
Published: August 2010

Ethanol was directly synthesized from dimethyl ether (DME) and syngas with the combined H‐Mordenite and Cu/ZnO catalysts that were separately loaded in a dual‐catalyst bed reactor. Methyl acetate (MA) was formed by DME carbonylation over the H‐Mordenite catalyst. Thereafter, ethanol and methanol were produced by MA hydrogenation over the Cu/ZnO catalyst. With the reactant gas containing 1.0 % DME, the optimized temperature for the reaction was at 493 K to reach 100 % conversion. In the products, the yield of methanol and ethanol could reach 46.3 % and 42.2 %, respectively, with a small amount of MA, ethyl acetate, and CO2. This process is environmentally friendly as the main byproduct methanol can be recycled to DME by a dehydration reaction. In contrast, for the physically mixed catalysts, the low conversion of DME and high selectivity of methanol were observed.
Nachhaltigkeit von neu errichteten Wohngebäuden — Wege zur Beschreibung und Bewertung
Authors: Vogler Ingrid
Published: August 2010

Seit längerer Zeit ist die Bewertung und Zertifizierung der Nachhaltigkeit von Gebäuden ein in der Fachöffentlichkeit intensiv diskutiertes Thema. Es besteht ein deutlicher Trend, Qualitäten messbar und damit öffentlich kommunizierbar zu machen. Dies wird auch von der Politik eingefordert. Der Wohnungsbau kann und will sich als quantitativ bedeutsamster Bereich des Bauens der Entwicklung hin zu komplexen Zertifizierungssystemen nicht verschließen. Für Wohngebäude sind aber wesentliche Unterschiede zu Bürogebäuden zu berücksichtigen. Wohnen und damit die Wohnung ist der Mittelpunkt menschlichen Lebens. Die soziale Dimension des Wohnens, der Wohnqualität und der Bezahlbarkeit des Wohnens haben daher essentielle gesellschaftliche Bedeutung. Wohnen ist sowohl Wirtschafts‐ als auch Umwelt‐ und Sozialgut. Die Wohnungswirtschaft untersucht deshalb gemeinsam mit weiteren Verbänden und dem BMVBS unter wissenschaftlicher Begleitung Möglichkeiten zur Beschreibung und Bewertung der Nachhaltigkeit von neu errichteten Wohngebäuden, die den Spezifika des Wohnens gerecht wird.

Sustainability of new residential buildings — ways to a description and quantification. For some time the description and certification of sustainability of buildings is an intensive discussed topic in the professional community. There is a clear trend for making qualities measurable and communicable to the public. This is demanded by the policy also. The housing sector as the quantitative most important part of civil engineering wants not to reject to complex certification systems. For residential buildings, however, significant differences to office buildings must be taken into account. Housing is the center of human life. The social dimension of housing, the housing quality and the affordability of housing have essential social significance. Housing has an economic, environmental and social dimension. Therefore the housing industry, together with other associations and the Federal Ministry of Transport, Building and Urban Development, and under scientific supervision, is working on possibilities for describing and quanti fying the sustainability of new residential buildings in accordance with the specifics of housing.
JNK phosphorylates Ser332 of doublecortin and regulates its function in neurite extension and neuronal migration
Authors: Jin Junghee , Suzuki Hiromi , Hirai Syu‐ichi , Mikoshiba Katsuhiko , Ohshima Toshio
Published: August 2010

Doublecortin (DCX) is expressed in young neurons and functions as a microtubule‐associated protein. DCX is essential for neuronal migration because humans with mutations in the DCX gene exhibit cortical lamination defects known as lissencephaly in males and subcortical laminar heterotopia (or double cortex syndrome) in females. Phosphorylation of DCX alters its affinity for tubulin and may modulate neurite extension and neuronal migra tion. Previous in vitro phosphorylation experiments revealed that cyclin‐dependent kinase 5 (Cdk5) phosphorylates multiple sites of DCX, including Ser332, (S332). However, phosphorylation at only Ser297 has been shown in vivo. In the present study, we examined phosphorylation of S332 of DCX in the Cdk5−/− mouse brain and results found, unexpectedly, indicate an increased DCX phosphorylation at S332. We found that JNK, not Cdk5, phosphorylates DCX at S332 in vivo. To examine the physiological significance of S332 phosphorylation of DCX in neuronal cells, we transfected cells with either GFP, GFP‐DCX‐WT, or GFP‐DCX‐S332A and analyzed neurite extension and migration. Introduction of GFP‐DCX‐WT enhanced neurite extension and migration. These effects of DCX introduction were suppressed when we used GFP‐DCX‐S332A. Treatment of neurons with JNK inhibitor increased the amount of DCX that bound to tubulin. Interestingly, amount of DCX that bound to tubulin decreased in Cdk5−/− brain homogenates, which indicates that phosphorylation of DCX by JNK is critical for the regulation of DCX binding to tubulin. These results suggest the physiological importance of phosphorylation of DCX for its function. © 2010 Wiley Periodicals, Inc. Develop Neurobiol 70: 929–942, 2010
A novel null allele of mouse DSCAM survives to adulthood on an inbred C3H background with reduced phenotypic variability
Authors: Fuerst Peter G. , Harris Belinda S. , Johnson Kenneth R. , Burgess Robert W.
Published: August 2010

DSCAMs are cell adhesion molecules that play several important roles in neurodevelopment. Mouse alleles of Dscam identified to date do not survive on an inbred C57BL/6 background, complicating analysis of DSCAM‐dependent developmental processes because of phenotypic variability related to the segregating backgrounds needed for postnatal survival. A novel spontaneous allele of Dscam, hereafter referred to as Dscam2J, has been identified. This allele contains a four base pair duplication in exon 19, leading to a frameshift and truncation of the open reading frame. Mice homozygous for the Dscam2J mutant allele survive into adulthood on the C3H/HeJ background on which the mutation was identified. Using the Dscam2J allele, retinal phenotypes that have variable severity on a segregating background were examined. A neurite lamination defect similar to that described in chick was discovered in mice. These results indicate that, in the retina, additional DSCAM‐dependent processes can be found by analysis of mutations on different genetic backgrounds. © genesis 48:578–584, 2010. © 2010 Wiley‐Liss, Inc.
CXCR3 blockade inhibits T‐cell migration into the CNS during EAE and prevents development of adoptively transferred, but not actively induced, disease
Authors: Sporici Romeo , Issekutz Thomas B.
Published: August 2010

Autoreactive T‐cell infiltration into the CNS is critical in MS and EAE. The chemokine receptor CXCR3 and its ligands are implicated in MS and mouse EAE, but the contribution of CXCR3 to T‐cell migration into the inflamed CNS remains controversial. During active disease in a rat EAE model, blood T‐cell, spleen T‐cell and T lymphoblast migration into the CNS was inhibited by a CXCR3 blocking mAb by, 30–70%, ∼75% and 50–80%, respectively. However, CXCR3 blockade after active immunization did not inhibit EAE, did not alter total T‐cell accumulation in the CNS and did not affect Treg accumulation or the presence of cells producing IFN‐γ or IL‐17. Conversely, CXCR3 blockade during EAE induced by adoptive transfer of myelin basic protein‐activated T cells delayed disease onset, shortened its duration and reduced disease severity. Moreover, CXCR3 blockade inhibited leukocyte infiltration of the CNS>95%, virtually abolishing infiltration of transferred T cells. Thus, CXCR3 plays a major role in T‐cell migration to the CNS and can be critical for encephalitogenic T‐cell migration into the CNS to induce disease, but CXCR3‐independent recruitment can also produce EAE.
Local recall responses in the stomach involving reduced regulation and expanded help mediate vaccine‐induced protection against Helicobacter pylori in mice
Authors: Becher Dorit , Deutscher Michael E. , Simpfendorfer Kim R. , Wijburg Odilia L. , Pederson John S. , Lew Andrew M. , Strugnell Richard A. , Walduck Anna K.
Published: August 2010

Helicobacter pylori is recognised as the chief cause of chronic gastritis, ulcers and gastric cancer in humans. With increased incidence of treatment failure and antibiotic resistance, development of prophylactic or therapeutic vaccination is a desirable alternative. Although the results of vaccination studies in animal models have been promising, studies in human volunteers have revealed problems such as ‘post‐immunisation gastritis’ and comparatively poor responses to vaccine antigens. The focus of this study was to compare the gastric and systemic cellular immune responses induced by recombinant attenuated Salmonella Typhimurium‐based vaccination in the C57BL/6 model of H. pylori infection. Analysis of lymphocyte populations in the gastric mucosa, blood, spleen, paragastric LN and MLN revealed that the effects of vaccination were largely confined to the parenchymal stomach rather than lymphoid organs. Vaccine‐induced protection was correlated with an augmented local recall response in the gastric mucosa, with increased proportions of CD4+ T cells, neutrophils and reduced proportions of CD4+ Treg. CD4+ T cells isolated from the stomachs of vaccinated mice proliferated ex vivo in response to H. pylori antigen, and secreted Th1 cytokines, particularly IFN‐γ. This detailed analysis of local gastric immune responses provides insight into the mechanism of vaccine‐induced protection.
The transmembrane adaptor protein NTAL signals to mast cell cytoskeleton via the small GTPase Rho
Authors: Tůmová Magda , Koffer Anna , Šimíček Michal , Dráberová Lubica , Dráber Petr
Published: August 2010

The transmembrane adaptor protein NTAL (non‐T‐cell activation linker) participates in signalosome assembly in hematopoietic cells, but its exact role in cell physiology remains enigmatic. We report here that BM‐derived mast cells from NTAL‐deficient mice, responding to Ag alone or in combination with SCF, exhibit reduced spreading on fibronectin, enhanced filamentous actin depolymerization and enhanced migration towards Ag relative to WT cells. No such differences between WT and NTAL−/− BM‐derived mast cells were observed when SCF alone was used as activator. We have examined the activities of two small GTPases, Rac and Rho, which are important regulators of actin polymerization. Stimulation with Ag and/or SCF enhanced activity of Rac(1,2,3) in both NTAL−/− and WT cells. In contrast, RhoA activity decreased and this trend was much faster and more extensive in NTAL−/− cells, indicating a positive regulatory role of NTAL in the recovery of RhoA activity. After restoring NTAL into NTAL−/− cells, both spreading and actin responses were rescued. This is the first report of a crucial role of NTAL in signaling, via RhoA, to mast cell cytoskeleton.
Directing traffic on the NKT‐cell highway: A key role for ThPOK
Authors: Chakravarti Sumone , Godfrey Dale I.
Published: August 2010

CD1d‐restricted NKT cells include CD4+ and DN subsets, with an additional CD8+ subset that is present in humans but not in mice. The molecular regulation of CD4/CD8 expression by NKT cells, and differentiation of these NKT‐cell subsets, is poorly understood. The transcription factors GATA3 and ThPOK regulate lineage commitment of conventional MHC class II‐restricted CD4+ T cells; however, their role in CD4/CD8 expression by CD1d‐restricted NKT cells is less clear. A new study in this issue of the European Journal of Immunology demonstrates a key role for ThPOK in differentiation of NKT‐cell subsets. This study reveals that GATA3 and ThPOK are necessary for the development of CD4+ NKT cells. Furthermore, ThPOK‐deficient mice generate an unusual population of CD8+ NKT cells, which are absent in control mice. This study sheds new light on the underlying molecular events leading to the emergence of distinct NKT‐cell subsets.
Tetranuclear Manganese Complexes with [MnII4] and [MnII2MnIII2] Units: Syntheses, Structures, Magnetic Properties, and DFT Study
Authors: Jerzykiewicz Lucjan B. , Utko Józef , Duczmal Marek , Starynowicz Przemysław , Sobota Piotr
Published: August 2010

Two tetranuclear manganese compounds, [Mn4(μ3,η2‐L)4Br4(LH)4] (1) and [Mn4(μ3,η2‐L)2(μ,η2‐L)4L2Br2] (2), with cubane and defect dicubane‐like cores were synthesized and characterized by single‐crystal X‐ray diffraction, magnetic measurements, and DFT calculations (LH = 2‐methoxyethanol). The magnetic properties of the resulting [Mn4] building blocks are presented and discussed in detail. In particular, in 2 the MnIII–O–MnIII angle 103.12(8)° is the largest observed to date for such a system. The conjunction of antiferromagnetic and ferromagnetic interactions within the tetranuclear mixed‐valent MnII2MnIII2 complexes results in an unusual ST = 1 ground state.
Shape Evolution and Tunable Properties of Monodisperse Magnetite Crystals Synthesized by a Facile Surfactant‐Free Hydrothermal Method
Authors: Liu Rongzheng , Zhao Yuzhen , Huang Rongxia , Zhao Yongjie , Zhou Heping
Published: August 2010

Monodisperse Fe3O4 crystals have been synthesized by a simple hydrothermal method. Reaction conditions are performed in an ethylene glycol (EG)/NaOH system using FeCl3 as the iron source without adding any surfactants. By adjusting the initial molar ratio of NaOH to Fe3+, several morphologies including solid spheres, hollow spheres, spherical chains, tetrakaidecahedrons, octahedrons, and some flowerlike structures can be obtained. Further investigation reveals that all of the spherical structures are formed by the highly oriented assembly of Fe3O4 nanoparticles. The evolution of the morphology from spheres to octahedrons can be attributed to the competition effect between ethylene glycol and NaOH under the reaction conditions. The saturation magnetization, coercivity, and remanent magnetization of the as‐synthesized samples vary as the morphology and grain size changes.
Polyoxometallate–Thiosemicarbazone Hybrid Compounds
Authors: Gil‐García Rubén , Zichner René , Díez‐Gómez Virginia , Donnadieu Bruno , Madariaga Gotzon , Insausti Maite , Lezama Luis , Vitoria Pablo , Pedrosa María R. , García‐Tojal Javier
Published: August 2010

New polyoxometallate–thiosemicarbazone hybrid compounds derived from pyridine‐2‐carbaldehyde thiosemicarbazone (HL), pyridine‐2‐carbaldehyde N4‐methylthiosemicarbazone (HL′) and their copper(II) complexes have been synthesized. Their formulae are (H2L)4(Mo8O26)(H2O)4 (1), [{(HL)2H}2(Mo6O19)]·C3H6O·0.24H2O (2), [(H2L′)4(HL′)2(Mo8O26)(H2O)2] (3), [{Cu(L)}4(Mo8O26)(H2O)4] (4), [{Cu(HL)(H2O)}2(Mo8O26)] (5), [{Cu(L′)}4(Mo8O26)(H2O)14] (6), Na6[{Cu(HL′)(H2O)2}4({Cu(L′)}2{Mo36O116(H2O)12})]·20H2O (7), [{Cu(HL)}2{Cu(L)}4{Mo36O112(H2O)16}(H2O)26] (8), [{Cu(HL′)}4{Mo36O112(H2O)16}(H2O)30] (9) and [{Cu(HL)(H2O)}2{Cu(L)S}2(H4V10O28)]n·6nH2O (10). Compounds 1–6 contain octamolybdate [Mo8O26]4– or hexamolybdate [Mo6O19]2– anions together with (H2L)+, (H2L′)+, [Cu(L)]+, [Cu(HL)(H2O)]2+ or [Cu(L′)]+ cations and neutral thiosemicarbazone molecules. The polyoxometallates (POMs) in 7–9 are [Mo36O116(H2O)12]16–, {Mo36} (7), and [Mo36O112(H2O)16]8–, {Mo36′} (8, 9). [Cu(HL′)]2+/[Cu(L′)]+ and [Cu(HL)]2+/[Cu(L)]+ units complete the respective lattices. Compound 10 consists of decavanadate anions (H4V10O28)2– and thiosemicarbazone‐copper(II) entities forming 1D [{Cu(HL)(H2O)}2{Cu(L)S}2(H4V10O28)]n structures connected through the hydrogen bonds of chains of water molecules. Structures of 2, 5, 7 and 10 have been characterized by single‐crystal X‐ray diffraction and other instrumental techniques (infrared, thermal analysis, electron paramagnetic resonance, nuclear magnetic resonance, magnetic susceptibility and mass spectrometry) were used to analyse all the compounds presented herein. The structural parameters of more than 1000 published thiosemicarbazone‐metal complexes have been used to determine some of the differences between metal complexes that contain anionic and neutral thiosemicarbazone ligands.
Copper(I) in the Cleft: Syntheses, Structures and Catalytic Properties of {Cu+–Co3+–Cu+} and {Cu+–Fe3+–Cu+} Heterobimetallic Complexes
Authors: Singh Amit Pratap , Gupta Rajeev
Published: August 2010

The present work demonstrates the synthesis and characterization of {Cu+–Co3+–Cu+} and {Cu+–Fe3+–Cu+} heterobimetallic complexes utilizing Co3+ and Fe3+ coordination complexes as the building blocks. The crystallographic investigation of the {Cu+–Co3+–Cu+} and {Cu+–Fe3+–Cu+} heterometallic complexes reveal that the CuI ions in the clefts are coordinated by two pyridine nitrogen atoms and one CH3CN molecule. The crystal structures also show several weak interactions that result in interesting packing in the solid state. The accessible Cu2+/+ redox potential and presence of labile site on the copper center has been utilized for the oxidation of hindered phenols in the presence of molecular oxygen. Hindered phenols were oxidized to the C–C‐coupled products in most cases, however, de‐alkylation resulted in the case of 2,4,6‐trisubstituted phenols. Interestingly, when H2O2 was used as oxidant, de‐alkylation was not observed; suggesting the uniqueness of the active species generated in the presence of catalyst and molecular oxygen.
TiO2 Nanotubes – Annealing Effects on Detailed Morphology and Structure
Authors: Albu Sergiu P. , Tsuchiya Hiroaki , Fujimoto Shinji , Schmuki Patrik
Published: August 2010

The present work deals with self‐organized TiO2 nanotube layers formed on a Ti metal substrate by anodization. For virtually any electrical or photoelectric application, these originally amorphous nanotube layers need to be converted to anatase. Most frequently, this is done by annealing at temperatures of approximately 450 °C. In the present work we use TEM and XRD to compare the annealing at a significantly lower temperature of 350 °C with that at the established 450 °C. HRTEM results show that both annealing treatments lead to comparable grain sizes in the nanotube walls; however, at 450 °C numerous defects (nanoscopic cracks) are created in the nanotube walls. Moreover, the treatment at 450 °C leads to the formation of a (rutile) oxide layer underneath the tube layers. These factors can considerably affect the overall properties of the tubes. Additionally, we point out some effects that should be carefully considered when using HRTEM investigation on TiO2 nanotubes such as e‐beam‐induced crystallization or tube diameter shrinkage.
Dimethyl Acetylenedicarboxylate and Phospholes: A Variety of Reaction Pathways
Authors: Huang Congbao , Liu Hui , Zhang Jianzhen , Duan Zheng , Mathey François
Published: August 2010

Correcting an earlier report, the reaction of 1‐phenyl‐3,4‐dimethylphosphole (1a) with an excess amount of dimethyl acetylenedicarboxylate (DMAD) at room temperature affords the stable cyclopentadienylidenephosphorane 3a resulting from unexpected deoxygenation of initially formed [phosphole + 2DMAD] adduct 2a by the starting phosphole. The identity of 3a was established by X‐ray crystal structure analysis. DFT calculations on a model [1+2] adduct similar to 2a shows a bent allenic structure and an ambident reactivity for the terminal carbon of the (DMAD)2 chain. Cyclopentadienylidenephosphorane 3b is also obtained with 1‐benzylphosphole 1b. With 1‐stannylphosphole 1c, a 1:3 adduct with a seven‐membered ring (i.e., 5) is obtained. It was also characterized by X‐ray crystal structure analysis. Finally, with 1‐benzyl‐2‐benzoylphosphole 1d, the P lone pair has lost its nucleophilicity and a [4+2] cycloaddition takes place with the dienol tautomer of the unsaturated ketone to give phosphindole 6, also characterized by X‐ray.
Modular Synthesis of 5‐Substituted Furan‐2‐yl C‐2′‐Deoxyribonucleosides and Biaryl Covalent Base‐Pair Analogues
Authors: Bárta Jan , Slavětínská Lenka , Klepetářová Blanka , Hocek Michal
Published: August 2010

A modular and efficient synthesis of 5‐(hetero)arylfuran C‐2′‐deoxyribonucleosides was developed. Friedel–Crafts C‐glycosidation of 2‐bromofuran with toluoyl‐protected methyl 2′‐deoxyribofuranoside in the presence of BF3·Et2O gave 5‐bromofuran C‐nucleosides, which were used as key intermediates for Stille or Suzuki coupling with (hetero)arylstannanes or boronic acids to afford a series of 5‐(hetero)arylfuran C‐nucleosides. 5‐Boronofuran C‐nucleoside was prepared by the Suzuki coupling of bromofuran with bis(pinacolatodiboron) or by Ir‐catalyzed C–H borylation of furan and was used for cross‐coupling with 5‐bromoheteroaryl C‐nucleosides to furnish novel covalent analogues of nucleoside pairs. The title 5‐arylfuran C‐nucleosides possess interesting fluorescence properties that may be applicable for fluorescent labeling of biomolecules.
Molecular Tweezers: Synthesis and Formation of Host–Guest Complexes
Authors: Legouin Béatrice , Gayral Maud , Uriac Philippe , Cupif Jean‐François , Levoin Nicolas , Toupet Loic , van de Weghe Pierre
Published: August 2010

A chiral molecular tweezer obtained from (+)‐usnic acid placed in solution in the presence of various aromatic compounds afforded complexes with low association constants. Thus, the X‐ray structure of assembly 3i is presented, where the guest is sandwiched between the two pincers of the tweezer. The association constants for various guests were determined through different methods. Finally, other tweezers with electron‐rich aromatic aldehydes and ketones were prepared from (1R,2R)‐1,2‐diaminocyclohexane. The most interesting complexes were also confirmed through structural analysis, and the best results were obtained with 10‐hydroxyphenanthrene‐9‐carbaldehyde (5i) as the aromatic moiety.
Kharasch‐Type Cyclizations of 2‐Substituted Indole Derivatives Surprisingly Lead to Spiroindoles
Authors: Van der Jeught Sarah , De Vos Nils , Masschelein Kurt , Ghiviriga Ion , Stevens Christian V.
Published: August 2010

Starting from 1H‐indole‐2‐carboxylic acid, a series of spiro[2‐oxoindole‐pyrrolidines] could be synthesized in a straightforward manner. The key reaction is a Kharasch radical cyclization reaction of trichloroacetylated precursors. The identity of the tricyclic final products that were formed could be determined as spiro[2‐oxoindole‐pyrrolidines] by using a combination of different analytical techniques (1H NMR, 13C NMR, gHMBC, HRMS) and additional reactions. The produced skeletons are interesting from a medicinal point of view.