bluuebunny/crossref_metadata_2025 huggingface dataset:
Metaverse Banking 2.0
Authors: Bhattacharya Saurabh , Singla Babita
Published: April 2024

The metaverse combines with reality and creates an alternate universe. The availability of technological advances enables us to perform new tasks or efficiently complete ordinary duties. The “metaverse,” or extended reality, opens up fresh opportunities for fascinating telepathy as well as has the potential to simplify routine tasks. As much as these technologies assist us in this work, education, healthcare, consumption, and pleasure, they also pose several challenges. The chapter tackles the questions of why and when customers will accept an entirely integrated area for a variety of operations, such as buying things and making purchases of Banking services. Examining the potential of Metaverse banking, this study looks into interesting avenues for future development that will influence how financial environments change in virtual spaces. The research anticipates a financial transformation with a focus on Blockchain, virtual assets, smart contracts, decentralized finance (DeFi), and immersive technology.
Prevalence of tobacco smoking and the knowledge and attitudes on prevention of tobacco smoking among schooling adolescents in the age group of 13 – 15 years in the Kandy district in 2018
Authors: Rambukwella H. W. S. R. , Dissanayake D. S.
Published: April 2024

Introduction: The early age of tobacco smoking initiation among adolescents reported in Sri Lanka highlights the need to initiate tobacco prevention at a very young age.Objectives: To determine the prevalence of tobacco smoking, the knowledge, and attitudes on prevention of tobacco smoking among schooling adolescents in government schools in the age group of 13-15 years in the Kandy district in 2018.Methodology: A cross-sectional study was conducted among 1395 students in selected government schools in the Kandy district. The subjects were selected using a stratified multi-stage cluster sampling method. A pretested self-administered questionnaire was used.Results: The response rate was 97.1%. The Prevalence of ever tobacco smoking in the age group of 13 to 15 years, was 6.02% (95% CI, 4.83% - 7.40%). The prevalence of current smokers was 4.16% (3.23% - 5.24%). Satisfactory knowledge of the harmful effects of tobacco smoking was shown by 49.6% (n=692) of ever smokers. The majority (71.5%, n=997) showed favourable attitudes towards the prevention of smoking. There was a higher likelihood of smoking among students who had unsatisfactory knowledge (OR = 8.203; 95% CI = 4.142 – 16.247) and attitudes (OR=1.172; 95% CI=1.112 – 1.225) compared to students who had satisfactory knowledge and attitudes.Conclusions: The prevalence of tobacco smoking in the selected age group was high in the Kandy district compared to the national rates. School interventions should target more students who already smoke to improve their knowledge and attitudes.
Autonomic and Vascular Function in Cardiovascular Health with Insights from COVID-19
Authors: Nandadeva D.
Published: April 2024

No abstract available
Lady With Painful Double Vision
Authors: Bandara J. M. R. P.
Published: April 2024

No abstract available
Effects of the Use of Beta-Blockers on Chronic Obstructive Pulmonary Disease Associated with Cardiovascular Comorbities: Systematic Review and Meta-analysis
Authors: dos Santos Natasha Cordeiro , Camelier Aquiles Assunção , Menezes Anne Karine , de Almeida Victor Durier Cavalcanti , Maciel Roberto Rodrigues Bandeira Tosta , Camelier Fernanda Warken Rosa
Published: April 2024

Cardiovascular comorbidity is common in individuals with chronic obstructive pulmonary disease (COPD). This factor interferes with pharmacological treatment. The use of β-blockers has been proposed for their known cardioprotective effects. However, due to their adverse reactions, and the risk of causing bronchospasm, there is reluctance to use them. To summarize existing evidence on the effects of β-blocker use in COPD associated with cardiovascular comorbidities in relation to disease severity, exacerbation, and mortality outcomes. EMBASE, Medline, Lilacs, Cochrane Library, and Science Direct databases were used. Observational studies that evaluated the effects of β-blockers on individuals with COPD and cardiovascular comorbidities, and related disease severity, exacerbations, or mortality outcomes were included. Studies that did not present important information about the sample and pharmacological treatment were excluded. Twenty studies were included. Relevance to patient care and clinical practice: The use of β-blockers in individuals with COPD and cardiovascular disease caused positive effects on mortality and exacerbations outcomes, compared with the results of individuals who did not use them. The severity of the disease caused a slight change in forced expiratory volume in 1 second. The odds ratio for mortality was 0.50 (95% confidence interval [CI], 0.39 to 0.63; p<0.00001), and for exacerbations, 0.76 (95% CI, 0.62 to 0.92; p=0.005), being favorable to the group that used β-blockers. Further studies are needed to study the effect of using a specific β-blocker in COPD associated with a specific cardiovascular comorbidity.
Functional Outcomes after Surgical Management of Peripheral AVM at a Tertiary Care Center
Authors: Neeli Sashidhar Deveekrishna , Kunapareddy Harikamal , Desai Sanjay C , Ramswamy Chandrashekar Anagavalli , Gowda Suhas Srinivas , Manchikanti Sriram
Published: April 2024

Introduction:

Arteriovenous (AV) malformations (AVMs) are rare vascular developmental orders containing an arterial network draining directly into one or more veins without a capillary bed, accounting for 1.5% of total vascular anomalies. Clinical presentations include pulsating mass, pain, ulceration, bleeding, tissue necrosis, enlargement of draining vein, and venous hypertension and/or cardiac failure. Treatment modalities include surgical excision, coil embolization, and sclerotherapy. Surgical excision offers an opportunity for cure but is associated with a risk of injury to vital structures, causing permanent impairment. Due to the high-risk nature of the lesion, it is important to study the clinical presentation and management of peripheral AVM for better management of these patients.

Objectives:

The objective was to study the presentation, management, and postoperative outcomes in terms of recurrence and functional status of the limb after surgical management of AVMs.

Patients and Methods:

It was a retrospective study done for 5 years (2018–2023). Thirteen patients who underwent surgical excision of peripheral AVM were included. Recurrence and functional status were assessed by clinical evaluation during follow-up outpatient department visits.

Conclusion:

The mean age of presentation is 33 years, with male preponderance (70%). Seven patients had upper limb AVMs (four had forearm involvement, while the rest had elbow region involvement). Six patients had lower limb AVMs, out of which four patients had involvement of the thigh region, one had in the knee, and the other in the calf. All patients complained of difficulty in performing daily activities due to the lesion. Nine patients underwent direct surgical excision, and four patients underwent AVM embolization before surgery (three patients had coil embolization, and one had onyx embolization). The mean duration of stay in the hospital was 5 days. Three patients were advised body contour stockings at follow-up. Two patients had recurrence (one after 6 months of surgical excision and the other had prior coil embolization), and one patient (had preembolization) had continued difficulty in walking postprocedure. The rest of the patients did not develop recurrence/functional impairment. There was no postoperative mortality. Thus, surgical excision offers a chance at cure with durable, functional outcomes in patients with peripheral AVMs.
Microglia lactylation in relation to central nervous system diseases
Authors: Yang Hui , Mo Nan , Tong Le , Dong Jianhong , Fan Ziwei , Jia Mengxian , Yue Juanqing , Wang Ying
Published: April 2024

The development of neurodegenerative diseases is closely related to the disruption of central nervous system homeostasis. Microglia, as innate immune cells, play important roles in the maintenance of central nervous system homeostasis, injury response, and neurodegenerative diseases. Lactate has been considered a metabolic waste product, but recent studies are revealing ever more of the physiological functions of lactate. Lactylation is an important pathway in lactate function and is involved in glycolysis-related functions, macrophage polarization, neuromodulation, and angiogenesis and has also been implicated in the development of various diseases. This review provides an overview of the lactate metabolic and homeostatic regulatory processes involved in microglia lactylation, histone versus non-histone lactylation, and therapeutic approaches targeting lactate. Finally, we summarize the current research on microglia lactylation in central nervous system diseases. A deeper understanding of the metabolic regulatory mechanisms of microglia lactylation will provide more options for the treatment of central nervous system diseases.
Perilipin-2 mediates ferroptosis in oligodendrocyte progenitor cells and myelin injury after ischemic stroke
Authors: Yang Jian , Wu Jiang , Xie Xueshun , Xia Pengfei , Lu Jinxin , Liu Jiale , Bai Lei , Li Xiang , Yu Zhengquan , Li Haiying
Published: April 2024

JOURNAL/nrgr/04.03/01300535-202507000-00024/figure1/v/2024-09-09T124005Z/r/image-tiff

Differentiation of oligodendrocyte progenitor cells into mature myelin-forming oligodendrocytes contributes to remyelination. Failure of remyelination due to oligodendrocyte progenitor cell death can result in severe nerve damage. Ferroptosis is an iron-dependent form of regulated cell death caused by membrane rupture induced by lipid peroxidation, and plays an important role in the pathological process of ischemic stroke. However, there are few studies on oligodendrocyte progenitor cell ferroptosis. We analyzed transcriptome sequencing data from GEO databases and identified a role of ferroptosis in oligodendrocyte progenitor cell death and myelin injury after cerebral ischemia. Bioinformatics analysis suggested that perilipin-2 (PLIN2) was involved in oligodendrocyte progenitor cell ferroptosis. PLIN2 is a lipid storage protein and a marker of hypoxia-sensitive lipid droplet accumulation. For further investigation, we established a mouse model of cerebral ischemia/reperfusion. We found significant myelin damage after cerebral ischemia, as well as oligodendrocyte progenitor cell death and increased lipid peroxidation levels around the infarct area. The ferroptosis inhibitor, ferrostatin-1, rescued oligodendrocyte progenitor cell death and subsequent myelin injury. We also found increased PLIN2 levels in the peri-infarct area that co-localized with oligodendrocyte progenitor cells. Plin2 knockdown rescued demyelination and improved neurological deficits. Our findings suggest that targeting PLIN2 to regulate oligodendrocyte progenitor cell ferroptosis may be a potential therapeutic strategy for rescuing myelin damage after cerebral ischemia.
Postnatal development of rat retina: a continuous observation and comparison between the organotypic retinal explant model and in vivo development
Authors: Hu Baoqi , Wang Rui , Zhang Hanyue , Wang Xiou , Zhou Sijia , Ma Bo , Luan Yan , Wang Xin , Chen Xinlin , Zhang Zhichao , Kang Qianyan
Published: April 2024

JOURNAL/nrgr/04.03/01300535-202503000-00033/figure1/v/2024-06-17T092413Z/r/image-tiff

The organotypic retinal explant culture has been established for more than a decade and offers a range of unique advantages compared with in vivo experiments and cell cultures. However, the lack of systematic and continuous comparison between in vivo retinal development and the organotypic retinal explant culture makes this model controversial in postnatal retinal development studies. Thus, we aimed to verify the feasibility of using this model for postnatal retinal development studies by comparing it with the in vivo retina. In this study, we showed that postnatal retinal explants undergo normal development, and exhibit a consistent structure and timeline with retinas in vivo. Initially, we used SOX2 and PAX6 immunostaining to identify retinal progenitor cells. We then examined cell proliferation and migration by immunostaining with Ki-67 and doublecortin, respectively. Ki-67- and doublecortin-positive cells decreased in both in vivo and explants during postnatal retinogenesis, and exhibited a high degree of similarity in abundance and distribution between groups. Additionally, we used Ceh-10 homeodomain-containing homolog, glutamate-ammonia ligase (glutamine synthetase), neuronal nuclei, and ionized calcium-binding adapter molecule 1 immunostaining to examine the emergence of bipolar cells, Müller glia, mature neurons, and microglia, respectively. The timing and spatial patterns of the emergence of these cell types were remarkably consistent between in vivo and explant retinas. Our study showed that the organotypic retinal explant culture model had a high degree of consistency with the progression of in vivo early postnatal retina development. The findings confirm the accuracy and credibility of this model and support its use for long-term, systematic, and continuous observation.
Handling missing data in research
Authors: Ranganathan Priya , Hunsberger Sally
Published: April 2024

Missing data are an inevitable part of research and lead to a decrease in the size of the analyzable population, and biased and imprecise estimates. In this article, we discuss the types of missing data, methods to handle missing data and suggest ways in which missing data can be minimized.
Dermatopathia pigmentosa reticularis: through the eye of dermoscope
Authors: Bansal Aditi , Kaur Navneet , Singh Aminder , Kaur Sukhjot
Published: April 2024

Dermatopathia pigmentosa reticularis is a rare ectodermal dysplasia characterized by a triad of generalized reticulate hyperpigmentation, noncicatricial alopecia, and onychodystrophy. We report a case of a 22-year-old male with characteristic features of the diagnostic triad and adermatoglyphia of palm and soles. On dermoscopic examination reticulated hyperpigmented spots, reticulated pigmented spots, monotonous pigmented spots, reticulated hypopigmented spots, with perifollicular hypopigmentation were observed. Dermoscopic findings of palm and soles showed hyperpigmented reticular pattern with dots and adermatoglyphia. Onychoscopy and trichoscopy are also discussed. Histopathology revealed orthokeratosis, epidermal atrophy, increase in melanin pigment in basal layers with vacuolization, and dermal pigmentary incontinence. Other inherited reticulate dermatoses such as Naegeli–Franceschetti–Jadassohn syndrome, dyschromatosis symmetrica hereditaria, and dyskeratosis congenita were considered in differential diagnosis and are discussed.
Association of sarcoidosis and vitiligo − sharing the autoimmune pathogenesis
Authors: Sharma Prateek , Ramesh V.
Published: April 2024

The coexistence of vitiligo and sarcoidosis, although uncommon, has been reported rarely, suggesting the role of plasmacytoid dendritic cells in generating abnormal immune responses by Th1 and Th17-released cytokines. Our case is an interesting one, describing the co-existence of vitiligo and sarcoidosis. This further strengthens the growing amount of data supporting the hypothesis that Th1 and Th17 cells both have a role in causing autoimmune disorders and broadens the list of diseases with which sarcoidosis is associated.
Bilateral nevus of Ota
Authors: Hegde Pallavi , Sarkar Rashmi
Published: April 2024

Nevus of Ota (NOO) is a dermal melanocytoses characterized by bluish-brown macules along the distribution of trigeminal nerve. Ocular involvement is observed in most of the patients in the form of scleral pigmentation. Also reported associations in this condition are iris/ciliary body pigmentation/glaucoma, ocular melanoma, etc. Hence, the terms nevus fusco-ceruleus ophthalmo-maxillaris and oculodermal melanocytosis are used to refer to this condition. Bilateral NOO is a rarely encountered condition, with only few scattered case reports in the literature. In this study, we report a rare presentation of bilateral NOO in four patients. The condition is important to recognize due to cosmetic concern it poses and limited treatment options.
Idiopathic eruptive macular pigmentation: a case series
Authors: Sahana Nemmar Chandrashekarabhatta , Loganathan Eswari , Raju Sahana P.
Published: April 2024

Idiopathic eruptive macular pigmentation (IEMP) is a rare disorder of pigmentation presenting with asymptomatic hyperpigmentation mainly in children and adolescents over face, neck, trunk, and extremities. Epidermal basal-cell pigmentation is observed on histopathology. It usually resolves spontaneously over months to years. Lichen planus pigmentosus and erythema dyschromicum perstans should be differentiated from IEMP. We report four cases of IEMP fulfilling the criteria proposed by Sanz de Galdeano et al. in 1996.
Prognostication of Weather Patterns using Meteorological Data and ML Techniques
Authors: Mathur Saksham , Kumar Sanjeev , Choudhury Tanupriya
Published: April 2024

In the field of modern weather prediction, the accurate classification is essential, impacting critical sectors such as agriculture, aviation, and water resource management. This research presents a weather forecasting model employing two influential classifiers random forest and technique based on gradient boosting, both implemented using the Scikit-learn library. Evaluation is based on key metrics including F1 score, accuracy, recall, and precision, with Gradient Boosting emerging as the superior choice for precipitation prediction. The study examines the performance of Random Forest Regression, Gradient Boosting Regression, and Radial Basis Function Neural Network in forecasting precipitation, drawing on prior research that demonstrated the superiority of the Random Forest algorithm in terms of accuracy and speed. Ensemble methods, particularly the Voting Classifier, a fusion of Random Forest and Gradient Boosting, outperform individual models, offering a promising avenue for advancing weather classification.
Research on Land-Based Wind/Solar Power Station Site Deformation Monitoring Based on SBAS-InSAR Technology
Authors: Guo Junke , Liu Ling , Zheng Yongfeng , Cai Wei , Wang Zhijun , Wang Shangqi
Published: April 2024

INTRODUCTION: In recent years, China has been building extensive wind/solar power stations. During the construction and operation of land-based wind/solar power stations, deformation monitoring is an important method to investigate the station stability.
OBJECTIVES: Therefore, this study uses Sentinel-1 data and time-series InSAR technology to monitor the deformation of photovoltaic and wind power stations in Qingyuan County.
METHODS: InSAR technology obtains deformation rate maps in the radar line of sight (LOS) direction for a wide area around the power station sites. Since wind/solar power stations are mainly located in natural environments with relatively dense vegetation coverage, this paper proposes a SBAS-InSAR method integrated with spatiotemporal filtering to accurately extract the time series deformation over a large area. Based on the statistical characteristic difference between the deformation and the atmospheric delay, spatiotemporal filterings are applied to remove the atmospheric delay from the InSAR derived deformation results.
RESULTS: The experimental results show that spatiotemporal filtering is an effective and fast method to remove atmospheric delay.
CONCLUSION: The integration of BSAS-InSAR with spatiotemporal filtering has great potential applications in the deformation monitoring of land-based wind/solar power station sites, which is critical for the construction and operation of land-based wind/solar power stations.
ANALISIS PERAMALAN JUMLAH PENERIMAAN MAHASISWA BARU DENGAN MENGGUNAKAN METODE REGRESI LINEAR SEDERHANA
Authors: Muhartini Ajeng Afifah , Sahroni Oman , Rahmawati Septi Dwi , Febrianti Tanti , Mahuda Isnaini
Published: April 2024

dalam perguruan tinggi Universitas Bina Bangsa banyak mahasiswa yang daftar menjadi mahasiswa baru di setiap tahunnya khususnya Prodi Manajemen Fakultas Ekonomi dan Bisnis, dalam hal ini analisis data prodi manajemen Universitas Bina Bangsa selama 5 tahun dari tahun 2015 sampai dengan 2019 memberikan akurasi setiap tahunnya. Pada penelitian ini adalah bertujuan untuk melakukan perkiraan untuk mengetahui banyaknya jumlah mahasiswa baru pada Prodi Manajemen Fakultas Ekonomi dan Bisnis menggunakan metode regresi sederhana linear. Sehingga dapat diketahui jumlah mahasiswa baru dimasa yang akan datang
IMPLEMENTASI KETERAMPILAN DIGITALISASI BAGI GURU TERHADAP KOMPETENSI PENGEMBANGAN MEDIA DAN BAHAN AJAR DI RA AL KAMILAH
Authors: Rini Dede , Sakti Universitas Panca
Published: April 2024

The use of information and communication technology (ICT) in teaching and learning process (PBM) is currently one of the alternatives in the learning process. ICT-based teaching materials are becoming more interactive means of explaining a material. With ICT developed learning materials equipped with multimedia facilities, so that its presentation can be more interesting and the material can be depicted visually so that the presentation of the material can be equipped with pictures, video and animation. Currently, there are many online media platforms that can be used in learning, one of which is YouTube. YouTube is a social media or video sharing website where there are several categories in video groupings such as entertainment, sports, education, and so on. By utilizing this YouTube application as a learning medium, it can improve the quality of learning
HUBUNGAN PROBLEM SOLVING APPRAISAL TERHADAP PENYESUAIAN DIRI NARAPIDANA ANAK DI LEMBAGA PEMASYARAKATAN KELAS II B RANGKASBITUNG
Authors: Maemunah Siti Erma , Hidayat Amat
Published: April 2024

Prison is a place of punishment for criminals who violate criminal law. Prisons are places where people are locked up and restricted in various ways. Jail for this child is something that will make everything lose. children will lose their families, lose the opportunity to play with their peers, lose the opportunity to learn at school, lack of stimulation, and can make child prisoners experience psychological disorders. This problem will make it difficult for children to accept the reality when they are in prison. When entering prison, child prisoners must be able to adapt to the prison environment, both with the prison, even other child prisoners, rules and regulations, as well as habits carried out in prison. To adapt to these problems and situations, child prisoners need a Problem Solving Appraisal to support the resolution of the problems they face. The purpose of this study was to examine the relationship between Problem Solving Appraisal and adjustment to child prisoners. The method used in this research is the correlation method with a quantitative approach. The results showed that there was a relationship between Problem Solving Appraisal and adjustment to prisoners in Class II B Rangkasbitung Correctional Institution with a correlation level of +0.473. Based on the results of the study, it can be interpreted that child prisoners who believe themselves to be Effective Problem Solvers are able to adjust well in Class II B Rangkasbitung Penitentiary
MANAJEMAN WAKTU BELAJAR SISWA BERPRESTASI KELAS V SD DI LINGKUNGAN RT 005/04 PULAU TIDUNG
Authors: Perdiansyah Perdiansyah , Widodo Slamet
Published: April 2024

This study aims to describe the management of learning time for outstanding students in fifth grade elementary school in RT 005/04 Tidung Island, South Thousand Islands. The research method used in this research is descriptive qualitative research method. The selection of the sample in this study used a purposive sampling technique, where the researcher chose a sample with certain considerations. The samples used in this study were 2 high achieving fifth grade students who were in the RT 005/04 Tidung Island, South Thousand Islands. The data collection techniques used are questionnaires or questionnaires and structured interviews. Meanwhile, the data analysis used the Miles and Huberman model analysis technique. The results of this study are, students who have good achievements have good time management such as having good short-term study plans, having a wise attitude in spending time, and having good long-term study plans, and getting very good support from his parents
PENGGUNAAN MEDIA FLASHCARD TERHADAP HASIL BELAJAR IPA SISWA SEKOLAH DASAR
Authors: Hazhari Alvan , Pamungkas Maya SIh Hika , Kurniawati Yetty
Published: April 2024

The problem of science learning outcomes that occur there are students who are less active/focused on learning material, difficulty memorizing material, students do not have strong motivation and interest, students feel bored in teaching and learning activities, lack of skill in using media in the learning process. so that the ability of science learning outcomes does not reach the KKM. The purpose of this study was to determine the use of Flashcard media on the science learning outcomes of elementary school students. The research method used is library research (literature study) from 10 journals and theses as primary library sources and 7 books as secondary libraries, the using Flashcard media on student science learning outcomes with intervals of the last ten years starting from 2012-2021. The results showed that the type of media used for students' science learning outcomes was Flashcard media that every research that had been carried out obtained percentage results that showed an increase in student learning outcomes, from the results of research conducted by previous researchers that the use of Flashcard media can improve learning outcomes. student science. The conclusion of this study is that there are positive results in learning in the use of Flashcard media on science learning outcomes
PERAN LEMBAGA PENJAMIN SIMPANAN TERHADAP SALDO UANG ELEKTRONIK PADA DOMPET ELEKTRONIK DANA
Authors: Anrova Yuda , Sembiring Albert
Published: April 2024

DANA is a technology for electronic wallet or e-wallet that is used for transactions without cash or cards but only with a user's start. That ease and effectiveness led to the high consumption of DANA. But lately electronic wallet users have concerns over the balance on their electronic wallets. Indonesian have Institution Lembaga Penjamin Simpanan (LPS) is regulated number 24 of 2004, it provides security and gives its customers confidence in existing systems and institutions. It is still a matter of whether LPS played a part in the transaction. The research aims to see the extent of LPS 'role in transactions in DANA applications. By using descriptive research methods of anaitis by using secondary data of legislation, previous research, and literature. The study shows that LPS has no role in the protection of public money that is kept in the application of DANA because legal regulations do not permit it. The LPS also have no intervention function in policy or financial transaction activities in the fund in DANA
Rivalitas Suami Istri Dalam Kontestasi Pemilihan Kepala Desa
Authors: P Achmad Nashrudin , Jumhana Enjum
Published: April 2024

The election of the Village Head (Pilkades) is a democratic phenomenon that has been a tradition since colonial times (Muis, 2006). As a phenomenon, the journey has been long enough until the reign of Joko Widodo period 2. The practice of democracy, requiring deliberation for consensus, based on the belief in family and gotong royong aimed at welfare that contains religious elements, based on truth, love and noble ethics and upholding the principles of democracy is equality, freedom, and pluralism. This paper aims to look at the background of the contestation of husband and wife in pilkades, its influence on the quality of democracy and the quality of political participation of rural communities. Using qualitative methods through phenomenological approaches and descriptive analysis, the results of the analysis, obtained the results of the analysis, that the opportunity to serve more than 2 times as Village Head in accordance with Law No. 6 of 2014 on Villages and the prohibition of single candidates, as well as the will to rule more than 2 times became the main reason husband and wife conducted a "fake" rivalry. Rivalries that ostensibly promote equality, equality and gender bias, undermine and degrade the value of democracy itself
TINDAK PIDANA KORUPSI DITINJAU DARI HAM DI INDONESIA
Authors: Putra Irwan Sapta
Published: April 2024

This study discusses the problem of corruption related to human rights violations that exist in Indonesia, Human Rights are a set of rights that are inherent in the nature and existence of humans as creatures of God Almighty and are His gift that must be respected, upheld and protected by state, law, government, and everyone for the sake of honor and protection of human dignity.
Eradication of Corruption Crimes carried out by the Corruption Eradication Commission (KPK) is currently being intensively carried out by the KPK, this can be seen from electronic media news, both printed and online.
From this news, we can see together that the KPK has never stopped carrying out its duties in eradicating corruption in Indonesia. Even though many perpetrators of corruption have been arrested by the KPK, this does not necessarily eliminate the crime of corruption, even though every year there are criminals who are arrested by the KPK.
The arrests of perpetrators of criminal acts of corruption by the Corruption Eradication Commission, ranging from high-ranking state officials such as the Minister and Chairman of the DPR RI to law enforcers (police, prosecutors, judges and advocates) as well as regional officials such as governors, mayors and regents and DPRD members also did not escape the arrests. by the KPK.
The crime of corruption is a crime that can be categorized as a crime of gross human rights violation because the impact caused by these criminal acts can disrupt the country's economy and also hinder the development of the country and even these crimes can also disrupt the world economy
IMPLEMENTASI SANKSI TERHADAP PELAKU TINDAK PIDANA PENADAHAN KENDARAAN BERMOTOR
Authors: Saputra Ponco Febri , Baharudin Baharudin , Anggalana Anggalana
Published: April 2024

Arrest is a crime that does not stand alone, but a crime that begins with a predicate crime. As for the problem in this research, how is the application of the law to the crime of arresting a motorized vehicle? Decision Number 451/Pid.B/2021/PN.Tjk. ? and What are the Factors Causing the Crime of Arresting Motor Vehicles in Decision Number 451/Pid.B/2021/PN.Tjk.?, the research method used is normative and empirical juridical, the results of research on Application of Law Against the Crime of Arresting Motor Vehicles Decision Number 451/Pid .B/2021/PN.Tjk The Public Prosecutor charged the Defendant with a single charge in accordance with Article 480 Paragraph (1) of the Criminal Code and the Panel of Judges sentenced the defendant Asep Junaedi Bin Abdulah (late) to imprisonment for 1 (one) year and 6 ( six months. Factors Causing the Crime of Arresting Motor Vehicles Decision Number 451/Pid.B/2021/PN.Tjk due to several supporting factors among these factors, namely, educational factors, economic factors, price factors, law enforcement factors and environmental factors, besides that Criminal acts of detention often occur due to the lack of socialization carried out to the community by law enforcement officials directly
TINJAUAN HUKUM PELAKSANAAN DAN PENGEMBANGAN SISTEM INFORMASI DESA (SID) DI KABUPATEN SERANG
Authors: Yusuf Muhamad , Muin Fatkhul , Karsa Pipih Ludia , Akmal Diya Ul
Published: April 2024

The aim of this study was to figure out how the Village Information System in Serang Regency was implemented and developed. There are 326 villages in Serang Regency, all of which have access to the Village Information System. The issue is that village data is slow to update, resulting in recipients of village funds not being on target or having to double-check their information. This study used the legal empirical method with normative data analysis. The data used are primary data (Interviews and Observations) and secondary data (Legislation, Books, Journals, and relevant materials sourced from the Internet) which are then processed and narrated using words with scientific logic. According to the findings of this study, villages in Serang Regency still do not take advantage of existing information systems. The Regional Government of Serang Regency must issue regional legal regulations to define the implementation and development of the Village Information System. Furthermore, each village must prepare human resources so that the Village Information System can be implemented quantitatively and managed effectively
Community-acquired pneumonia in young children living in various climatogeographic zones of the Republic of Dagestan
Authors: Arslanova Ayzarhanum Yu. , Aliskandiev Alaudin M. , Slutskaya Mariya D. , Aliskandieva Zuleykhat A.
Published: April 2024

Introduction. Community-acquired pneumonia (CAP) in early childhood continues to cause significant morbidity and remains one of the most common serious infections in childhood. Each region of the Russian Federation exhibits specific manifestations of CAP morbidity. Knowledge of CAP etiology is crucial for planning therapeutic and preventive measures.
Aim. To determine the etiological and immunological features of CAP in early childhood, residing in various climatogeographical zones of the Republic of Dagestan.
Materials and methods. The material includes the results of examination and treatment of CAP 204 young children. living in lowland, foothill and mountain climatogeographical zones of the Republic of Dagestan. The selection criterion was the clinical-radiological diagnosis of CAP, using the classification of clinical forms of bronchopulmonary diseases in children.
Results. The study revealed a rise in the incidence of respiratory organ diseases, including CAP, among children in the Republic of Dagestan (RD) over the past 5 years. Among infants under one year, the CAP rate was twice as high. The prevalence can be attributed to the climatogeographical conditions of children’s living environments. Streptococcal infection was also observed to predominate in the ethnostructure of CAP in early childhood across all climatogeographical zones. Streptococcus pneumoniae (48.1%) was more frequently isolated in all climatogeographical zones, while Staphylococcus aureus (13.3%) dominated in the mid-mountain zone. In mild pneumonia, cellular immunity components, represented by reduced CD3, CD4, CD25, CD71, react primarily. Disease exacerbation leads to depletion of CD8, CD16, CD20. Severe pneumonia triggers the involvement of humoral immunity, leading to changes in clinical blood analysis — leukocytosis and an increase in mature and immature forms of neutrophils. The levels of IL-1, IL-6, IL-8 in blood serum increase depending on the area of inflammation and the CAP severity. In observed children with focal-draining and segmental CAP, their levels significantly increased. For empirical antibacterial therapy of CAP, recommendations include amoxicillin, protected ampicillins, third-generation cephalosporins, macrolides, and vancomycin in mono- or combination therapy.
Conclusion. The conducted research highlights the need for managing ethnological monitoring with antibiotic sensitivity testing of infectious agents causing CAP in children.
Polymorphic substitutions in folate cycle genes as predictors of hyperhomocysteinemia in children
Authors: Strozenko Lyudmila A. , Ponomarev Viktor S. , Lobanov Yuriy F. , Dorokhov Nikolay A. , Sukmanova Irina A. , Shevchenko Karina I. , Skudarnov Evgeniy V. , Sanina Olga O.
Published: April 2024

Introduction. Mutant alleles of genes of folate cycle enzymes can lead to the significant deterioration of its function and varying severity of pathology. Several defects in these genes lead to severe hyperhomocysteinemia, the most common form of which is a deficiency of cystathionine beta-synthase B.
Aim: to establish polymorphic substitutions in the genes of folate cycle enzymes that contribute to the formation of hyperhomocysteinemia in children.
Materials and methods. Two hundred seventy one children aged of 13–18 years were examined. The analysis of genetic polymorphisms of the folate cycle was carried out using a molecular genetic method. Quantitative determination of the blood homocysteine and folic acid level was performed by chemiluminescent immunoassay on microparticles. Statistical data processing was carried out using Statistica 6.1 application programs (StatSoft Inc., USA).
Results. The frequency of the T allele of the MTHFR 677 gene was revealed to be higher in adolescents of the main group compared with the control (p = 0.043). The frequency of the homozygous genotype 66 AA of the MTRR gene in children of the comparison group was significantly higher (p = 0.049), however, the heterozygous genotype 66 AG of the MTRR gene was significantly more often detected in adolescents of the main group (p = 0.008). The average concentrations of homocysteine in children of the main group were 11.6 mmol/L, in adolescents of the control group 9.3 mmol/L (p = 0.021). Hyperhomocysteinemia in children of the main group was detected in 217 (80.1%) adolescents, and in 57 (49.6%) children of the control group (p < 0.001). The baseline serum folate level was determined in the children of the main group. The average amount of vitamin B9 in the blood of children of the main group was 3.7 ng/ml, and in 145 (53.5%) children this indicator was significantly reduced.
Conclusion. Low levels of folic acid contribute to an increase in homocysteine in blood plasma. Taking vitamin B9 and vitamin folate complexes significantly reduces the level of homocysteine in blood plasma (p < 0.001).
A influência das monoaminas -dopamina e serotonina- na capacidade de realizar o exercício físico
Authors: Rabelo Patricia da Conceição Rocha
Published: April 2024

A capacidade de realizar o exercício físico é influenciada por diversos fatores, dentre eles a concentração e atividade das monoaminas, tais como dopamina e serotonina. Esses neurotransmissores modulam vários sistemas fisiológicos que interfere na resposta hormonal, controle do movimento, termorregulação e motivação para o esforço. Assim, compreender a forma como as monoaminas interferem na capacidade de se exercitar pode ser fundamental para que estratégias sejam traçadas afim de melhorar o desempenho físico. Diante do exposto, o objetivo deste estudo é realizar uma revisão de literatura sobre a influência das monoaminas na capacidade de realizar o exercício físico.
As tendências da inteligência artificial para a educação
Authors: Carvalho Aline dos Santos Moreira de , Silva Leonardo da , Ribeiro Filho Afonso Celso Sampaio , Cellin Joelma
Published: April 2024

Este artigo científico investiga as tendências emergentes da inteligência artificial (IA) no contexto educacional, explorando seu impacto e potencial transformador. Abordando áreas-chave, o estudo destaca as tendências da personalização do aprendizado, assistentes virtuais, gamificação, análise preditiva e ética na integração da IA na educação. Essas ferramentas baseadas em IA proporcionam respostas personalizadas, contribuindo para uma comunicação eficiente e enriquecedora.A gamificação e o aprendizado baseado em jogos são abordagens que utilizam a IA para criar experiências educacionais mais interativas e motivadoras. Ao introduzir elementos lúdicos, essas técnicas buscam estimular o interesse dos alunos, tornando o processo de aprendizagem mais atrativo.A ética na inteligência artificial educacional é uma consideração essencial. Em síntese, este estudo proporciona uma visão abrangente das tendências da inteligência artificial na educação, evidenciando seu papel transformador. Este artigo tem como objetivo analisar e discutir as tendências emergentes no campo da inteligência artificial (IA) aplicada à educação. Por meio de uma revisão abrangente da literatura atualizada, serão exploradas as inovações tecnológicas e metodológicas que estão moldando a integração da IA no cenário educacional. O foco principal será identificar as principais tendências, desafios e oportunidades associadas à utilização da inteligência artificial para aprimorar processos de ensino e aprendizagem. Além disso, o artigo visa fornecer insights valiosos para educadores, pesquisadores e profissionais interessados no papel crescente da IA na evolução da educação, visando contribuir para o avanço do conhecimento e práticas nesse domínio dinâmico.
Paciente cardiaco con asistolia: un reporte de caso
Authors: Luna Magaly , Morgado María , Pogyo Gloria
Published: April 2024

La asistolia, o paro cardíaco, es el cese del corazón de una persona en este momento, el tiempo es muy importante, se debe actuar de inmediato y prescribir el tratamiento adecuado. La asistolia es causada por enfermedades y condiciones que pueden ser específicas del corazón (enfermedad coronaria) o no cardíacas (trauma, hemorragia, asfixia e intoxicación). El objetivo es determinar el manejo de pacientes con asistolia para introducir aspectos nuevos o educativos de la enfermedad. La metodología que se utilizó un método descriptivo retrospectivo con una técnica de recolección de historia clínica que revisó antecedentes patológicos, antecedentes personales, signos y síntomas, causa de la asistolia y tratamiento dado al paciente. Los resultados con base en la revisión de la historia clínica del paciente con asistolia, se encontró que se trataba de una parálisis de funciones sistémicas causada por cambios en el músculo cardíaco, por lo que se realizaron maniobras para reanimar el corazón., pero en el segundo episodio no lo supero, la asistolia continua y el paciente muere. Las conclusiones que este estudio proporcionó todas las bases legales para la recopilación de datos, la identidad preservada en todos los reclamos, respaldado por la verificación científica Scopus, Pubmed para la discusión relevante. Eventualmente, se concluyó que solo una de cada 100 personas que sufren de asistolia morirá.
Prevalencia del Síndrome de Burnout en Internos Rotativos de Medicina de un Hospital de Latacunga
Authors: Tacle Humanante Silvio Stalin
Published: April 2024

El burnout de los médicos se considera una epidemia y tiene efectos negativos en la atención médica y la seguridad del paciente; por lo que, el presente estudio tiene como objetivo determinar Síndrome de Burnout y su impacto en el desempeño laboral de los internos de un Hospital de la ciudad de Latacunga; para lo cual se efectuó una investigación metodológica de tipo descriptiva, correlacional Los datos se recopilaron a través de dos cuestionarios que fueron aplicados a 45 internos rotativos que laboran actualmente, obteniendo como resultado que existe una prevalencia de burnout del 40%. Además, en general el desempeño laboral es promedio y finalmente, los resultados de los análisis correlacionales indican que existe una relación positiva entre todas las dimensiones del desempeño y el burnout; esto implica que a medida que se mejora los índices de burnout se obtendrá un mejor desempeño laboral en los trabajadores.
Re-actualization of Traditional Themes in Contemporary Craft Art through the Concept of Hybrid Aesthetics
Authors:   Doctoral Program, Performing Arts and Visual Arts Studies, Universitas Gadjahmada, Indonesia, Ernawati Ernawati , Margana Sri ,   Universitas Gadjahmada, Indonesia, Marianto M. Dwi ,   Institut Seni Indonesia Yogyakarta, Indonesia
Published: April 2024

In the beginning, craft as a category of art was established because of its traditional cultural elements. However, in its development, contemporary craft art features many other styles and elements of art, making it difficult to distinguish craft art from other types of art. To adjust to the development and new characteristics of contemporary craft art, it is necessary to develop new methods in the creation of craft art. One of them is cultural hybridization. This article offers a method of creation by adopting the concept of a hybrid aesthetic. Through this method, artists are invited to experiment with visually re-actualizing traditional cultural elements in the creation of craft works among modern art elements. The main question that needs to be asked is how the hybrid aesthetic method can provide certain strength in reaffirming the definition of craft art according to the development of contemporary art. The adoption or application of the hybrid aesthetic concept in the creation of contemporary craft must still consider traditional elements and the adoption of other elements with the application of new methods of creation. The hybrid aesthetic concept produces a unique genre and has the opportunity to sustain an aura of originality through the re-actualization of traditional elements in a strong visual in the global art scene.
Marketing Communication Technology Innovation and its Implications on Increasing Sales (Griya Reyna Furniture Kediri Online Case Study)
Authors:   Faculty of Economics and Business, Kadiri University, Indonesia, Kristanti Nabilla Deva , Laely Nur ,   Faculty of Economics and Business, Kadiri University, Indonesia, Rukmini Meme ,   Faculty of Economics and Business, Kadiri University, Indonesia
Published: April 2024

The most important thing in the world of online business is to determine the innovation and technology of marketing communication, so that it can achieve certain goals. With the existence of marketing communication technology, entrepreneurs will be easier to market the products they will sell to potential customers in order to achieve the goals desired by marketers.qualitative research methods are research methods based on philosophy, used to examine in a natural object condition, (as opposed to experiments) where researchers are as key guidelines, data collection techniques are carried out in combination, Data analysis is qualitative, and qualitative research results emphasize the meaning of generalizations. The development of increasingly sophisticated technology, online business owners must also keep up with the times, with this communication technology, online business owners are easier and more practical to introduce their products. What used to be still marketing through word of mouth is now through social media and platforms that can be used in terms of marketing. With this communication technology we can do marketing effectively and efficiently, minimize costs, easily reach the general public, easily transact easily and quickly that Griya Reyna Furniture uses communication technology in terms of marketing through promotion mix, namely by advertising, personal selling, direct marketing, social media marketing, e-commerce, marketplace.