bluuebunny/crossref_metadata_2025 huggingface dataset:
ESTRATÉGIA DE TRANSFERÊNCIA DE TECNOLOGIA ENTRE UNIVERSIDADE PÚBLICA E EMPRESAS PRIVADAS A PARTIR DO MODELO DE NEGÓCIOS HÉLICE TRÍPLICE
Authors: Dos Santos Carlos Henrique Calixto , Santa Rita Luciana Peixoto , Pinto Filho Jovino , Bittencourt Ibsen Mateus
Published: June 2023

O objetivo do estudo foi o de elaborar uma proposta de modelo para negociação com o mercado sobre transferência de tecnologia dos ativos de esporte gerados pelo Instituto de Educação Física e Esporte (IEFE) da Universidade Federal de Alagoas, a partir da tríplice hélice. Foi utilizada a pesquisa bibliográfica e documental, tendo abordagem qualitativa por se tratar de coleta e avaliação das informações com uma variação do Business Model Canvas, com respaldo de Osterwalder e Pigneur (2011). Para dar conta do modelo de interação governo-universidade-empresa, houve o apoio teórico de Valente (2010); Mazzucato e Penna (2016); Almeida (2005); Oliveira, et. al. (2017); Willerding (2020), dentre outros. O trabalho possui relevância por possibilitar a compreensão do modelo de negócio de transferência de tecnologia adequado para o IEFE, potencializando a negociação dos ativos passíveis de transferência de tecnologia do instituto, além de mostrar a lógica de geração de valor na negociação com o mercado. Foi disponibilizada uma plataforma criada a partir do modelo de negócio com informações necessárias para a negociação de transferência de tecnologia, que pode ser adaptada para gerar uma minuta de contrato inicial que consolide a negociação da transferência de tecnologia. O modelo de negociação de transferência de tecnologia apresentou uma proposta robusta de informações que pode contribuir com as áreas de contratos, hélice tríplice e de negociação de ativos.
Computational Protein Design - Where it goes?
Authors: Xu Binbin , Chen Yingjun , Xue Weiwei
Published: June 2023

Proteins have been playing a critical role in the regulation of diverse biological
processes related to human life. With the increasing demand, functional proteins are
sparse in this immense sequence space. Therefore, protein design has become an important
task in various fields, including medicine, food, energy, materials, etc. Directed evolution
has recently led to significant achievements. Molecular modification of proteins
through directed evolution technology has significantly advanced the fields of enzyme engineering,
metabolic engineering, medicine, and beyond. However, it is impossible to
identify desirable sequences from a large number of synthetic sequences alone. As a result,
computational methods, including data-driven machine learning and physics-based
molecular modeling, have been introduced to protein engineering to produce more functional
proteins. This review focuses on recent advances in computational protein design,
highlighting the applicability of different approaches as well as their limitations.
A Comprehensive Exploration of Metabolism and Tumor Microenvironment
and Immunotherapy Response: Evidence From Large Populations in
Non-small Cell Lung Cancer
Authors: Chen Baorong , Hou Qinghua , Liu Linzhuang , Wu Liusheng , Wang Hanwen , Lai Xinyi , Liu Haozhen , Li Xiaoqiang , Liu Jixian
Published: June 2023

Aims:

The study aimed to explore the effect of metabolism on lung cancer.

Background:

The tumor microenvironment is largely influenced by metabolism, tightly involved in
tumor progression.

Objective:

We try to investigate the effect of tumor metabolism terms on non-small cell lung cancer
(NSCLC) prognosis, drug and immunotherapy sensitivity, as well as its underlying mechanisms.

Methods:

All the data was obtained from The Cancer Genome Atlas and Gene Expression Omnibus
databases. R software was used to perform all statistical analyses and plots.

Results:

This study conducted 21 metabolism statuses in NSCLC to identify their underlying roles.
We found that alpha-linolenic acid metabolism, sphingolipid metabolism, glycerophospholipid metabolism,
fatty acid degradation, linoleic acid metabolism, primary bile acid biosynthesis, and fatty acid
metabolism were protective factors for NSCLC. Next, we constructed a prognosis model based on
primary bile acid biosynthesis, glycerophospholipid, and sphingolipid metabolism. Results in the present
study showed that our model could effectively predict patients' prognosis in both training and validation
cohorts. A clinical correlation revealed that patients at high-risk exhibited more progressive
clinical characteristics. Biological enrichment indicated that MYC targets, E2F targets, mTORC1 signaling,
G2/M checkpoint, and epithelial-mesenchymal transition were activated in the high-risk group.
Immune relation analysis showed that risk score positively correlated with Th2 cells, yet a negative
correlation with CD56 bright NK, Th17, mast and CD8+ T cells. Moreover, our model was related to
NSCLC patients' sensitivity to immunotherapy and chemotherapy. Ultimately, eight characteristic
genes were identified to distinguish the patients' risk group in the real application.

Conclusions:

The model we developed is a useful tool to predict NSCLC patients' prognosis and is
associated with the sensitivity of immunotherapy and chemotherapy. Meanwhile, our results can guide
the following metabolism-related studies in NSCLC.
The Tumor Microenvironment Affects Circulating Tumor Cells Metastasis
and the Efficacy of Immune Checkpoint Blockade in Non-small Cell Lung
Cancer
Authors: Zhang Xiuxiu , Qiu Sheng , Wang Cailian
Published: June 2023

Lung cancer is one of the most lethal malignancies, with non-small cell lung cancer
(NSCLC) being the most common histologic subtype. Metastasis leads to poor prognosis for patients
with cancer. Tumor cells leave the tumor lesions, invade the surrounding stroma, and enter the bloodstream
as circulating tumor cells (CTCs). The development of CTCs is the beginning of metastasis.
The internal environment in which tumor cells grow and survive is called the tumor microenvironment
(TME). It includes tumor cells, fibroblasts, immune cells, and the extracellular matrix. The TME is
complex and dynamic. Moreover, the TME plays an important role in tumor development and metastasis
and significantly impacts therapeutic outcomes. Immune checkpoint blockade (ICB) aims to inhibit
the interaction of ligands with their corresponding receptors. ICB has the function of restoring
the anti-tumor effect of immune cells. This review examines how TME interacts with CTCs, allowing
CTCs to evade immunity and facilitating CTC metastasis. TME not only affects the progression of
tumor metastasis but also interacts with tumor cells, which may affect the efficacy of immunotherapy.
Hypertension-Mediated Organ Damage In Young Patients With First-Diagnosed And Never Treated Systolic Hypertension
Authors: Benas Dimitris , Triantafyllidi Helen , Birmpa Dionyssia , Fambri Anastasia , Schoinas Antonios , Thymis Ioannis , Kostelli Gavriela , Ikonomidis Ignatios
Published: June 2023

Objective:

Early onset of untreated arterial hypertension is associated with an increased risk
for cardiovascular (CV) diseases. The evaluation of hypertension-mediated organ damage (HMOD)
helps estimating CV risk. We investigated the incidence of HMOD in young first, diagnosed and nevertreated
patients with systolic arterial hypertension (SH) to identify high CV-risk patients based on the
presence of HMOD.

Methods:

CV risk factors [smoking, obesity (body mass index, BMI)], hyperlipidemia and 5 HMODs
[arterial stiffness (pulse wave velocity, PWV), left ventricular diastolic dysfunction [(DD (E/Ea)], cardiac
hypertrophy (left ventricular mass index, LVMI), coronary artery microcirculation (CFR), and carotid
intima-media thickness (cIMT)] were evaluated before treatment initiation in 220 patients, aged ≤50
years [median (interquartile range, IQR) age=43(38-47)], with SH diagnosed by ambulatory blood pressure
monitoring (24-h ABPM).

Results:

Smoking (40%) and obesity [median (IQR) BMI=30(26-32) kg/m2](40%) were found in young
hypertensives. HMOD was found in 50% of hypertensives (10% had ≥2 HMOD). The most prevalent
HMODs were increased by cIMT (32%) and PWV (19%), LVH (9%), impaired CFR (6%) and DD
(1%). Only PWV (beta=0.27, p<0.001) and LVMI (beta=0.41, p<0.001) were associated with systolic
BP burden. In a subgroup analysis, patients with ≥2 HMOD were older with increased office BP and 24-
h ABPM, impaired lipid profile, and increased LVMI, PWV, CFR, and cIMT compared with the rest of
the hypertensives.

Conclusion:

The presence of ≥2 of the studied HMOD (PWV, LVMI, cIMT, E/Ea, CFR) in young hypertensives
characterizes a “high-risk population”. Arterial stiffness represents the predominant HMOD
and in the whole population and "high-risk population".
Advances in Chemistry of 2-(Piperazin-1-yl) Quinoline (Part IV)
Authors: El-Bana Ghada G. , Gouda Moustafa A.
Published: June 2023

This review described the preparation of 2-(piperazin-1-yl) quinoline derivatives from 2-
haloquinolines and anilides, which underwent alkylation, arylation, acylation, and reductive amination
to form the 2-piprazinoquinolines. 2-(Piperazin-1-yl) quinoline used as building blocks for the
synthesis of polyfunctionalized heterocyclic compounds with pharmacological interest.
Berbamine Inhibits the Biological Activities of Prostate Cancer Cells by Modulating
the ROS/NF-κB Axis
Authors: Zhao Wanli , Jiang Yuqing , Jia Xiaopeng , Wang Xiuli , Guo Yuexian
Published: June 2023

Background/Introduction:

Prostate cancer ranks as the second leading cause of cancer death. No effective
pharmacological agent is available for prostate cancer treatment. Berbamine is an alkaloid extracted from the Chinese
herb berberis, which exerts an effect on inhibiting cancer cell proliferation.

Objective:

This study aimed to explore the mechanism of berbamine in inhibiting prostate cancer.

Methods:

Prostate cancer cell lines PC-3 and DU145 cells were used to evaluate the effects of berbamine. Cell viability
was determined using cell-counting kit 8. The intracellular reactive oxygen species (ROS) levels were measured
using a ROS assay kit. Cell apoptosis rate was examined using flow cytometry. The protein levels associated with cell
proliferation, NF-κB pathway, and apoptosis were determined using western blot.

Results:

It was found that berbamine induced cell cycle arrest in the S phase and inhibited prostate cancer cell growth
and proliferation. Berbamine inhibited prostate cancer cells by inhibiting the activation of the NF-κB pathway in vitro.
Berbamine increased ROS as an upstream molecule that inhibited the NF-κB pathway.

Conclusion:

Our results demonstrated that berbamine can effectively reduce the proliferation of prostate cancer cells.
The ROS/NF-κB axis plays a crucial role in berbamine-mediated anti-prostate cancer cell proliferation.
Cine Tauro: una isla lujuriosa en el caos limeño. Sujetos y valores patrimoniales en torno al objeto moderno
Authors: Dordan Barboza Katherine , Kohama Aréstegui Carolina , Suárez Robles Gustavo , Yalán Reyes Ivan
Published: June 2023

El objetivo del presente artículo es presentar el desarrollo de la investigación del caso: Cine Tauro: una isla lujuriosa en el caos limeño. Sujetos y valores patrimoniales en torno al objeto moderno. Esta investigación tiene por objetivo principal el entender las razones por las cuales el cine Tauro, un proyecto representante de la modernidad de la arquitectura peruana de inicios de la década de 1960, quedó aislado, decadente y agonizante en el oficialmente llamado ambiente urbano monumental del siglo XX del Cercado de Lima.
Aura Inés Del Águila Ríos
Authors: Hayakawa Casas José
Published: June 2023

Realizó estudios de Educación e Historia en la Pontificia Universidad Católica del Perú optando el grado de Doctor en educación. Así mismo, estudió cursos de Museología y Museografía dictados por ICOM – Perú además de la Maestría en Gestión cultural y museología de la Universidad Ricardo Palma. Fue Directora y es asesora ejecutiva del Museo de Arqueología “Josefina Ramos de Cox” del Instituto Riva Agüero de la Pontificia Universidad Católica del Perú, cargo que ocupa desde 1995. Ejerció la coordinación del Seminario Permanente de Arqueología de Selva (SEPAS). Ha sido miembro Consejero del Patronato del Parque de las Leyendas, y miembro honorífico del comité científico del Parque de la Leyendas Fue la presidenta fundacional de la Red de Museos del Centro Histórico de Lima y de la Asociación Nacional de Museólogos del Perú (ANAMUP). Actualmente es miembro del Comité científico de la revista indizada sobre patrimonio edificado DEVENIR de la Facultad de Arquitectura de la Universidad Nacional de Ingeniería.
Machupicchu. Investigaciones interdisciplinarias. Tomo I y II
Authors: González Madueño Consuelo
Published: June 2023

Durante los últimos años se han venido desarrollando investigaciones  en el  Santuario Histórico-Parque Arqueológico Nacional de Machupicchu (SHM-PANM) de manera  científica y constante, producto de ese trabajo se publica MACHUPICCHU,  una  compilación histórica - arqueológica de 39 artículos, que publica  la Dirección Desconcentrada de Cultura de Cusco. La mayor parte de los textos son fruto de las investigaciones desarrolladas en el marco del Programa de Investigaciones Arqueológicas e Interdisciplinarias en el Santuario Histórico de Machupicchu, entre los años 2013 y 2017. Lo relevante de esta publicación es  dar a conocer que el Santuario está compuesto por cerca de 60 monumentos, incluyendo andenes, centros ceremoniales, caminos, canales y otras muestras arquitectónicas. Dada la dificultad de reseñar todos los artículos, nos referiremos sólo a los que consideramos más representativos.
patrimonio cultural y la identidad zacatecana
Authors: Alfaro Aucca Crayla
Published: June 2023

El libro que reseñamos es resultado de la actividad académica del Grupo de Investigación Historia e Interpretación del Patrimoniode la Universidad Autónoma de Zacatecas, una publicación estructurada en cuatro capítulos que a su vez congrega ocho artículos, de profesionales especialistas en el tema cultural, los cuales constituyen, sin duda, una valiosa contribución al reconocimiento y valoración del patrimonio material e inmaterial zacatecano como base de su construcción social e identitaria.
Carlos Pernaut
Authors: Gabriela Santibañez María
Published: June 2023

El patrimonio latinoamericano se vistió de luto con la partida del arquitecto Carlos Pernaut a sus 74 años. Nació en Buenos Aires, Argentina, el 8 de marzo de 1947 y transitó su vida con un compromiso ejemplar hacia el patrimonio y la formación profesional. Cursó la carrera de Arquitectura en la Universidad de Buenos Aires y egresó en 1975. Su proceso formativo no se detuvo allí, dedicó sus primeros años profesionales a especializarse en el campo de la conservación del patrimonio. Fue así como el mismo año de su titulación fue becado por la Unesco para perfeccionarse en Cusco, en materia de conservación del patrimonio arquitectónico. Impulsado por su interés en profundizar saberes se trasladó a Europa, donde se especializó en conservación a escala urbana e inventario del patrimonio en el novel Centro de Estudios Superiores de Historia y Conservación de Monumentos Antiguos, la reconocida Ecole Chaillot en París, fundada en 1887 por Anatole de Baudot, discípulo de Eugene Viollet-le-Duc. También cursó estudios en el Centro de Estudios para la conservación del patrimonio arquitectónico y urbano, en el prestigioso College d’Europe, Université Catholique de Louvain, Brujas, y finalizó su recorrido en la Scuola di Specializzazione in Restauro dei Monumenti, Università degli Studi, en Nápoles, Italia.
Graciela Mota Botello
Authors: Hayakawa Casas José
Published: June 2023

Doctora en Filosofía y maestra en Psicología Social por la Universidad Autónoma de México (UNAM). Académica desde 1979, distinguida con la medalla del mérito Universitario por sus 40 años en la UNAM. Coordinadora de la Investigación “¿Dónde se encuentra el espíritu del lugar?”. De su autoría, son más de 288 publicaciones científicas individuales y en coautoría, en libros y revistas nacionales e internacionales. Investigadora titular del posgrado en la Facultad de Psicología. Ponente y conferencista en más de 570 eventos nacionales e internacionales, ha asistido a 470 eventos especializados para completar su actualización, y a su vez ha organizado 152 eventos académicos.
Declaración de Boceguillas: Principios para el estudio, la protección y la conservación de la Arquitectura Tradicional
Authors: Ramos Chuquimia Diana
Published: June 2023

El valor de este estudio radica en la difusión de la precaria situación y el peligro de desaparición en que se encuentra esta clase de arquitectura. Los autores alertan sobre la grave amenaza que han supuesto, además, las innumerables intervenciones sin criterio alguno de que ha sido objeto en muchos lugares; continúan resultando especialmente alarmantes en el momento actual.
El Ordenamiento del territorio en el valle de Moche. Lectura espacial de la Vida de las sociedades Prehispánicas”
Authors: Moreno Ahumada Carlos
Published: June 2023

La investigación presentada en el libro, sobre el ordenamiento territorial en el Valle de Moche, nos brinda nuevas perspectivas en los campos de la planificación territorial y urbana, la resiliencia, la sostenibilidad, la identidad e incluso una mejor lectura e interpretación histórica de la arquitectura desarrollada en el Perú.
Donato Amado Gonzales
Authors: Samanez Argumedo Roberto
Published: June 2023

El reciente deceso del historiador e investigador cusqueño conmovió a los círculos intelectuales y académicos vinculados a la conservación del patrimonio cultural y la investigación histórica. Su sentida desaparición ocurrió cuando había cumplido 60 años y estaba en el mejor momento de su producción, por lo que se esperaba mucho más de su intelecto.
Perceived psychological reactions to second wave of pandemic COVID-19 Among Working Adult Indonesians: An online survey study
Authors: Ridwan Edi Sampurno , Indrayana Sofyan , Badrujamaludin Asep , Supriadi Dedi , Huda Nuh , Priyanto Priyanto , Saidah Qori Ila , Sutandi Aan
Published: June 2023

Background: The Corona Virus Disease (Covid-19) pandemic caused serious health consequences including mental health issues. Thus, gaining insight into the emergence of mental health problems including fear, anxiety and stress in society during the second wave Covid-19 pandemic is imperative. 

Objectives: This study aimed to identify the psychological reactions of working Indonesians living in five metropolitan cities in Java Island and its association with personal characteristics during the second wave Covid-19 pandemic.

Methods: This cross-sectional study included a total of 916 respondents from five metropolitan cities in the Island of Java that was voluntarily completing the anonymous online survey. The data were administered by using the Indonesian version of Perceived Stress Scale (PSS), Covid-19 Anxiety Scale (CAS), and Fear of Covid-19 Scale (FCS). Bivariate and multivariate analysis were performed using non-parametric methods due to non-normal distribution data. Significance for hypothesis testing was set with p-value 0.05 on 95% Confidence Interval. Data was analyzed using software STATA14 of StataCorp.

Results: A total of 916 respondents were included, with the median of age being 28 years old. Perceived fear and anxiety to Covid-19 among working individuals was low (35.92% and 40.94%), yet they were on moderate and high-levels of stress (31.88% and 45.52%) respectively. After adjusted all predictors, age was a significant predictor to the level of fear (p< 0.001), anxiety (p= 0.05), and stress (p< 0.001). The first dose of vaccination significantly predicted a reduction in the fear of Covid-19 (p= 0.045).

Conclusions: Increasing a year of age predicted the reduction of fear, anxiety, and perceived of stress to Covid-19. First dose vaccination significantly reduced the fear to Covid-19. 
Objective pulse changes in menstrual cycle：A scoping review (Preprint)
Authors: Wang Ce
Published: June 2023

BACKGROUND

Pulse diagnosis is an indispensable part of traditional Chinese medicine(TCM) diagnosis, which contains rich physiological and pathological information. However, pulse diagnosis in traditional Chinese medicine is too subjective to unify standards and easy to cause deviation. In recent years, the objectification of pulse diagnosis has achieved considerable development. It have conducted sufficient data collection and oscillogram specific analysis and research on a variety of diseases in the fields of liver disease, kidney disease, tumor, obstetrics and Gynecology, skin and other disciplines. However, there is still much work to be done with to establish the industry standard of pulse condition with the help of pulse diagnostic apparatus.

OBJECTIVE

To summarize the clinical research status of objective pulse changes in menstrual cycle using a scoping review.

METHODS

A systematic search of literature databases was conducted up to March 30, 2023.We searched articles on the objectification of pulse diagnosis related to female menstrual cycle.The following search terms were used for searching databases:('pulse graph parameter*' OR 'pulse diagnosis' OR 'pulse characteristic parameters' OR 'pulse nonlinear dynamics characteristics' OR 'pulse figure parameters') AND ('menstruation' OR 'menstrual cycle')

RESULTS

A total of 7 studies were included, 6 of which are in Chinese，one is in English. The changes of pulse in menstrual cycle of healthy women were studied. In terms of outcomes, 3 studies used pulse graph parameters, 4 used pulse names, and 2 used custom criteria.

CONCLUSIONS

At present, there is no unified pulse diagnostic instrument of medical devices for clinical research in China. It is suggested to encourage the research of three probe pulse detector to objectify pulse diagnosis and make the pulse diagnosis more consistent with the traditional pulse resection; Establish a unified use standard of pulse diagnostic instrument and pulse evaluation index as soon as possible. Future research might consider focusing on long-term, well-designed to evaluate pulse changes in individualized menstrual cycle.
Association Between Urinary Bisphenols and Body Composition Among American Adults: Cross-Sectional National Health and Nutrition Examination Survey Study (Preprint)
Authors: Li Jiakun , Zhang Zilong , Zhang Chichen , Zhu Qiyu , Zhao Jing , Zong Hui , Deng Qi , Zheng Jiaming , Wu Erman , Wu Rongrong , Tang Tong , Zhang Yihang , Dong Qiaosen , Li Yifan , Wang Jiao , Yang Lu , Qiu Shi , Shen Bairong , Wei Qiang
Published: June 2023

BACKGROUND

Bisphenol A (BPA), bisphenol S (BPS), and bisphenol F (BPF) are widely used in various consumer products. They are environmental contaminants with estrogenic properties that have been linked to various health outcomes. Understanding their impact on body composition is crucial for identifying potential health risks and developing preventive strategies. However, most current studies have only focused on their relationship with BMI.

OBJECTIVE

This study aimed to investigate the association between urinary levels of BPA, BPS, and BPF and body composition, including BMI, lean mass, and fat mass, in a large population-based sample.

METHODS

We conducted a cross-sectional analysis using data from the National Health and Nutrition Examination Survey 2003-2016. Body composition data were assessed using dual-energy X-ray absorptiometry, which provided precise measurements of lean mass, fat mass, and other indicators. We used multivariate linear regression models to estimate the associations, adjusting for potential confounders such as age, gender, race, socioeconomic factors, and lifestyle variables.

RESULTS

The results revealed significant associations between bisphenol exposure and body composition. After adjusting for covariates, BPS showed a positive association with BMI, with quartiles 3 and 4 having 0.91 (95% CI 0.34-1.48) and 1.15 (95% CI 0.55-1.74) higher BMI, respectively, compared with quartile 1 (P<.001). BPA was negatively associated with total lean mass (TLM) and appendicular lean mass, with quartiles 2, 3, and 4 having –7.85 (95% CI –11.44 to –4.25), –12.33 (95% CI –16.12 to –8.54), and –11.08 (95% CI –15.16 to –7.01) lower TLM, respectively, compared with quartile 1 (P<.001). BPS was negatively associated with TLM, with quartiles 3 (β=–10.53, 95% CI –16.98 to –4.08) and 4 (β=–11.14, 95% CI –17.83 to –4.45) having significantly lower TLM (P=.005). Both BPA and BPS showed a positive dose-response relationship with trunk fat (BPA: P=.002; BPS: P<.001) and total fat (BPA: P<.001; BPS: P=.01). No significant association was found between BPF and any body composition parameter.

CONCLUSIONS

This large-sample study highlights the associations between urinary levels of BPA and BPS and alterations in body composition, including changes in lean mass, fat mass, and regional fat distribution. These findings underscore the importance of understanding the potential health risks associated with bisphenol exposure and emphasize the need for targeted interventions to mitigate adverse effects on body composition.

CLINICALTRIAL
Keterampilan literasi informasi pustakawan Universitas Negeri Malang dalam implementasi layanan berbasis inklusi sosial
Authors: Inawati Inawati , Setiawan Setiawan , Prasetyawan Adi
Published: June 2023

Introduction. Inclusion-based libraries aim to improve information literacy, quality of life, and community welfare, as well as become a place for lifelong learning. The librarians need to have sufficient information literacy skills in implementing social inclusion-based services.

Data Collection Methods. Qualitative case study approach was used. The data was collected by interviews, observations, and documentation from librarians at the Malang State University Library.

Data Analysis. We analyzed our data by using data reduction, data presentation, and conclusion.

Results and Discussion. Information literacy skills of librarians were examined by several indicators such as identify, scope, plan, gather, evaluate, manage, and present. Those indicators have not been applied, particularly to the implementation of social inclusion-based services. Five indicators of information literacy skills can be applied properly including identification of needs information, determining the scope of information needs, planning information retrieval strategies, gathering information sources, as well as evaluating. In this study, skills in managing and presenting information have not been implemented properly.

Conclusion. The information literacy skills of librarians in social inclusion-based services have not been maximized due to absence of competency development, lack of librarians, and absence of collections and facilities that support all information needs based on the user.
Pengaruh motivasi terhadap perilaku knowledge sharing pegawai di Badan Pusat Statistik wilayah Sulawesi Tengah
Authors: Astuti Sri , Rachmawati Tine Silvana , Rusmana Agus
Published: June 2023

Introduction. The insufficient level of understanding of statistical indicators is indicated by the low level of knowledge sharing culture among BPS employees in the Central Sulawesi region. In this case, BPS needs to encourage the employees to participate in knowledge sharing activities. Individual's willingness to share knowledge can be influenced by several factors, one of them is motivation. The main objective of this paper is to understand the influence of motivation to employee’s knowledge sharing activities in BPS. A conceptual model is designed based on the Theory of Reasoned Action (TRA).

Data Collection Methods. A quantitative-explanatory research method was applied including literature study, data collection, and data analysis.

Data Analysis. The study used the structural equation modeling-partial least squares (SEM-PLS) analysis method with a sample of 174 samples.

Results and Discussion. Motivation has a positive-significant effect (p-value <0.05) on attitudes (β = 0.713) and employee intentions (β = 0.218). This has implications for employee knowledge sharing behavior (β = 0.758). Motivation and attitude can predict the intention by 42.7%, meanwhile, the intention can predict behavior by 57.5%.

Conclusion. To predict the knowledge-sharing behavior of employees, a sufficient motivation is needed to develop positive attitudes and strong intentions in each employee.
Peran kepala sekolah dalam pengelolaan perpustakaan untuk mendukung pembelajaran di masa pandemi COVID-19
Authors: Setiawan Setiawan , Qalyubi Syihabuddin , Laugu Nurdin
Published: June 2023

Introduction. This research is to examine perspectives of  teachers, students and librarians toward leadership roles regarding information technology development in school libraries in supporting learning in the era of the COVID-19 pandemic.

Data Collection Methods. This study used a quantitative descriptive approach with 100 respondents. The sampling technique used the probability sampling with simple random sampling method.

Results and Discussion. The role of school leaders in developing library governance has not yet been significant so that libraries could not contribute effectively to the learning process. During the pandemic, the role of IT is needed by teachers and students, particularly for the library users to finish their assignment from home. Users also need to have the library updates regarding books.  Many teachers and students do not understand how to use of information technology in the library including how to access or search information (online).

Conclusion. School leaders play an active role in improving the quality of the library as a source of learning to create benefits for the school community. The discussion on the abnormal situation leadership among school leaders.
Reading Oppression and Repression in Jean Rhys' Wide Sargasso Sea
Authors: Borthakur Harshita
Published: June 2023

Annette and Antoinette were unwelcomed by all. They “were not in their (the white people’s) ranks” and “The Jamaican ladies never approved” (Rhys 3) of them. As Creoles, they had no root. Being of colour and not belonging to the prevalent binary structure, they never fit in. Neither the whites accepted nor the blacks. Throughout they were mistreated and suffered in the hands of both. While Charlotte Bronte's Jane Eyre (1847) represents the unfit monster in Bertha, Jean Rhys' Wide Sargasso Sea (1966) re-presents the story leading to Bertha's present state. The journey from innocence to madness was forced onto the ‘monster’ of Bronte's Jane Eyre through various means and Rhys’ counter to the gothic romance provides an opportunity to re-read the disregarded characters in their ‘natural’ habitat, far from the cold and gloomy London. Their marginalization is realized through Rhys. The plot arouses the curiosity of the reader, illuminates the unheard story of the Creoles and brings into light the possible reasons for their ‘downfall’. This paper is an attempt to make an inquiry of the oppression faced by the ‘Others’, its impact on their psyche and the repression that led them to the doorstep of insanity. Through the means of a discursive study, it delves into the reasons for their degraded physical and mental state. The study employs the theoretical lens of Edward Said’s “Other” and Sigmund Freud’s “Trauma” to reach the desired analysis.
Creencias, actitudes y prácticas del médico en rol de paciente: perspectivas en República Dominicana
Authors: Nouri Kandany Vahid , Peña Núñez Melani , Aponte Báez Erick , Pimentel Brito Darlin , Toribio González Jaily , Gómez Muñoz Heidy
Published: June 2023

El mito existente sobre la ausencia de vulnerabilidad en los médicos hace que estos sean más difíciles de manejar en su rol de paciente. Así mismo, en ocasiones sus conocimientos previos los hacen tener creencias, actitudes y prácticas no favorables. En este artículo se presentan los resultados de un estudio descriptivo, de corte transversal, cuyo objetivo fue determinar las creencias, actitudes y prácticas del médico dominicano en el rol de paciente. En el mismo se aplicó una encuesta virtual que generó un total de 238 respuestas. Como resultado, se observó que, en su mayoría, los médicos consideran que es más difícil tratar como paciente a un colega. Sobre sus creencias y actitudes, las mismas suelen ser favorables en sus labores como médico, sin embargo, actitudes como la automedicación y los cambios de receta fueron notorios. En conclusión, se entiende que es necesario realizar estudios similares a este y concientizar a quienes se desempeñan como médicos en cuanto a esta temática.
Tamizaje de niveles tensionales en individuos no hipertensos entre 18-65 años en la comunidad de Pizarrete Abajo, municipio Nizao, provincia Peravia, República Dominicana, durante el período agosto-septiembre 2018
Authors: Barreto Nicole , Vásquez Emely , Rodríguez Alejandra , Lanurias Alan
Published: June 2023

Introducción: la presión arterial elevada es el principal factor de riesgo de enfermedad global. En la República Dominicana el 31 % de la población padece de hipertensión arterial (HTA) y de este, un 60 % lleva tratamiento médico.

Objetivo: determinar los niveles tensionales en individuos no hipertensos entre 18-65 años en la comunidad de Pizarrete Abajo, durante el período agosto-septiembre 2018.

Metodología: estudio prospectivo, descriptivo y de corte longitudinal, en el que se analizaron 85 individuos que residen en la comunidad de Pizarrete Abajo, de los cuales 44 resultaron con niveles tensionales alterados.

Resultados: el 51.7 % de los encuestados presentó niveles de tensión arterial alterados, sin haber sido anteriormente diagnosticado con hipertensión arterial. Un 24 % de las personas mostró niveles alterados una semana después de la primera toma de presión arterial.

Conclusiones: en una muestra de 85 personas se encontraron niveles tensionales alterados en 44 individuos. Se procedió a una segunda toma de presión arterial una semana después de la primera y se observó que un 56.8 % correspondió a valores tensionales elevados, un 20.4 % a valores de HTA estadio 1 y un 18.1 % a valores de HTA estadio 2.
Prediction of Alzheimer’s Dementia Disease Stages and Cognitive Scores Using Machine Learning and Deep Learning
Authors: S Kavyashree
Published: June 2023

Abstract: The most frequent form of dementia which is characterized by a low deterioration of memory, thinking, actions, and social skills, is Alzheimer's disease (AD). Those alterations have a ripple effect on an individual's ability to fulfil their duties. According to present thinking, the erroneous protein build-up in and around brain cells present thinking, the erroneous protein build-up in and around brain cells ultimately causes Alzheimer's disease. AD is not restricted to people over 65; it also affects individuals of all ages. The brain diminishes as the outcome of Alzheimer's disease, and subsequently, brain cells die away. In the early stages of the illness, victims exhibit modest memory loss, which is followed by a decrease in their capability to verbally interact and converse. While there is no curative treatment for the disease, early identification could decrease the severity of the illness and permit patients to lead quality lives. Alzheimer's disease, which particularly impacts elderly individuals and advances neurodegenerative, is a significant factor that leads to dementia. The disease can be divided into 5 stages: Cognitively Normal (CN), Mild Cognitive Impairment (MCI), Early MCI (EMCI), Late MCI (LMCI), and Alzheimer’s Disease (AD). These stages are predicted using a well-developed AlexNet model and an OASIS dataset is utilized to predict Cognitive Scores based on the Mini-Mental State Examination (MMSE) using different machine learning algorithms.
Image Captioning Using Deep Learning
Authors: Reddy Paidimarla Naveen
Published: June 2023

Abstract: Consequently making the description or title of an picture utilizing any common dialect sentences could be a exceptionally challenging assignment. It requires both strategies from computer vision to get it the substance of the picture and a dialect show from the field of common dialect preparing to turn the understanding of the picture into words within the right arrange. In addition to that we have examined how this demonstrate can be implemented on web and will be open for conclusion client as well. Our venture points to implement an Picture caption generator that responds to the client to induce the captions for a given picture. The extreme reason of Picture caption generator is to create user’s encounter way better by producing mechanized captions. We can utilize this in picture ordering, for outwardly disabled people, for social media, and a few other common language processing applications. Profound learning strategies have illustrated stateof-the-art comes about on caption era issues. What is most impressive almost these strategies could be a single end-to-end show can be characterized to foresee a caption, given a photo, rather than requiring advanced information planning or a pipeline of specifically planned models.
Hydroponics to Survive on Mars
Authors: N Gayathri
Published: June 2023

Abstract: Background: Determining the requirements and availability of food when we move to Mars would be a huge problem as most of our other alternative to food growth on Mars does not have a good cost-to-benefit ratio. Carrying or moving food for us to Mars would be environmentally implausible and Materials and Methods: The traditional method of hydroponics was used with the alteration of making the atmosphere suitable for Mars, with the required lighting, pressure and temperature was setup to recreate growing plants on Mars . Results: The results obtained showed lower weight and nutrient value thatn the control specimens , the plants that were grown in soil. Conclusion: The lower results can be attributed to the
Post Graduate Admission Prediction Using ANN
Authors: Bhrugubanda Meenakshi , Udutha Varsha , Yella Sri Charan
Published: June 2023

Abstract: Nowadays, we see many students showing interest in higher studies away from their home countries. Generally, students often lack sufficient knowledge about the requirements, procedures, specific details of universities in countries like the USA, UK, Canada, etc. As a result, they often turn to education consultancy firms for assistance in securing admission to universities that best align with their profiles. However, this process typically requires significant financial investment in consultancy fees. The objective of this project is to create a system using Artificial Neural Network (ANN) which helps to predict the percentage of chance of admittance of students by utilizing the various test attributes like GRE, TOEFL, Research papers etc., that will assist students in assessing the likelihood of their university applications being accepted i.e., it helps them to know about what is the chance of getting admission in reputed Foreign Universities. An intuitive user-friendly interface will be developed for the users to determine their chances of admission to a university by entering their various scores.
Regeneration and Rejuvenation of Water Bodies in the City of Bhawanipatna
Authors: Sahu Mr. Adarsh Kumar , Swain Ms. Swapna Sarita , Rout Mr.Piyush Ranjan
Published: June 2023

Abstract: Water is one of the essential resources for human survival.it is also a precious national resource linked to every aspect of development. With less than 3% of the Earth's water being fresh, the need to conserve and manage it is crucial. Global warming, climate change causes inadequate rainfall which are the reason for the water stress condition of india.it effect the level of water in ponds and lakes and eventually dries them up. Water bodies like lakes and ponds are integral for drinking water, agriculture, and urban purposes. Assessing freshwater resources and implementing conservation measures are essential for sustainable development. Watershed development, rainwater harvesting, and water recycling are essential for sustainable water supply in the coming future. Regeneration and rejuvenation of water bodies are important for sustainable development of cities and town as they help in water conservation, ground water recharge, improve climatic conditions, supports bio-diversity, etc. In which community plays important role in the regeneration and rejuvenation process. Bhawanipatna is the city and the districts headquarter of the Kalahandi district in the Indian state of Odisha. These water bodies both big and small have an inseparable impact on the aestheticity and operational functionality of the city. They are a vital part of the temperature regulatory mechanism and help the city in various other ways. Bhawanipatna, having highest population growth in the Kalahandi District, faces an imminent and acute water scarcity due to the lack of development as compared to other cities. Asha Sagar Pond which is located at the epicenter of Bhawanipatna has a significant amount of land cover that impacts the lifestyle and influences the microclimate of the study area. Implementation of water management scheme with local community participation is essential for sustainable urban development of cities and towns. Restoration methods such as preventive and ameliorative method can help in overcoming water scarcity at a micro to city level. There is a growing concern in many quarters that the world is running out of water. According to the United Nations Development Programme (UNDP) Human Development Report 2006, for over a billion people around the world, water access is unreliable, unsafe or beyond their purchasing power (UNDP, 2006). Urban areas in India are facing a water crisis due to loss of watershed, increasing levels of pollution, deteriorating water balance, lowering of water table and a dire lack of groundwater recharge (Singh, 2012). Regeneration and rejuvenation of water bodies are important for sustainable development of cities and town as they help in water conservation, ground water recharge, improve climatic conditions, supports bio-diversity
Cloud Based Bus Pass System
Authors: Arya Sagar , Saini Mansvi , Panwar Tanu , Kumar Avinash , Sharma Sanjeev
Published: June 2023

Abstract: The Real-Time Cloud-Based Bus Pass System Project serves as a convenient solution for commuters who are encountering difficulties with the current manual bus pass system. It allows passengers to travel easily with a mobile ticket QR code, which they can display if they lose their ticket during inspections. The QR code can be checked by the Train Ticket Examiner (TTE) and the system administrator to verify its authenticity. The system assigns a unique number to each passenger, preventing duplication. It also extends the validity period and sends timely alerts to the commuters through SMS or email before the expiry of their pass. Renewal or registration can be done using various payment methods, including credit or debit cards. Initially, passengers need to register with the application by submitting their personal details, including their photo and address proof, online. The system will review the information and approve or reject the bus pass application accordingly. Additionally, renewal can be performed using credit card or other payment methods.
An Experimental Study on Translucent Concrete
Authors: Ingale Komal
Published: June 2023

Abstract: This experimental study of translucent concrete which has the property of transmitting light from concrete by using optical fibers. Since years concrete has a low impression because of its dirty greyish colour , opaqueness and sharp edge but this concept has been changed after the development of light emitting concrete, which gives the increased strength, better looks and light transmitting features. Plastic optical fibers are used because of its total internal reflection as its working principle as it gives maximum efficiency in transmitting light. This report deals about the introduction of translucent concrete, materials used for making translucent concrete such as fine concrete, cement, optical fiber and procedure of making is also discuss for translucent concrete. After the study of different research paper results respected to 5%, 10% and 15% replacement of aggregate with optical fiber is discuss in this study.
College Enquiry Chat Bot Using Machine Learning
Authors: Shanthi Dr. A. S.
Published: June 2023

Abstract: To develop a college enquiry Chatbot that answers any queries post by students like college details, course-related questions, location of the college, fee structure etc. The College Enquiry Chatbot project is built using Deeplearning, Neural Network with Natural Language Processing that analyze user’s queries and understand the user's message. This System is a web application that provides answers to the query. Any individual just has to query through the bot. The answers are appropriate to what the user queries.
Physico - Chemical Studies of Indian Crude Oil
Authors: Patel Kunal , Patel Jinal , Nagar Ashish
Published: June 2023

Abstract: Crude oil is a complex mixture of non-metallic components like Sulphur, Nitrogen, Oxygen, and other elements with hydrocarbons. Crude oil is distinguished by several chemical and physical features that play an essential role in the oil industry. These qualities are critical in making decisions in the exploration and production of crude oil. Heavy crude oil is highly viscous crude oil with high Asphaltene content and API in the range of 10-25. Especially, transportation of Heavy Crude oil is herculean task for Petroleum industry. As a result, the study of physical and chemical properties becomes crucial for the petroleum industry. The current work deals with the investigation of physico-chemical characteristics of Indian crude oil.
How Agro-Waste Could Help to Solve the Beauty Industries Packaging Waste Problem
Authors: Joshi Nivavari , Nayak Dr. Bighna Kalyan
Published: June 2023

Abstract: In recent years, concerns about environmental sustainability have become increasingly important in many industries. The beauty industry, in particular, has been criticized for its high levels of waste. Beauty companies are responsible product significant amounts of waste from plastic packaging to unused products. However, there may be a solution in an unexpected place: agro-waste. The beauty industry could reduce its environmental impact and move towards more sustainable practices by utilizing materials such as fruit peels and natural fibers Sustainable packaging is becoming increasingly important in today's world. Not only does it help companies reduce their carbon footprint, but it also preserves natural resources that might otherwise be depleted.. Adopting sustainable packaging practices can also have tangible benefits for companies, including cost savings and increased customer loyalty. Developing packaging materials from agricultural waste can address both environmental and economic challenges. With the use of agro-waste, packaging materials are biodegradable, have a lower carbon footprint, and are cost-effective. By utilizing agro-waste, companies can also provide a new source of income for farmers and reduce the amount of waste that ends up in landfills. Furthermore, agricultural waste-based packaging can enhance a company's brand image and contribute to a more sustainable future.