bluuebunny/crossref_metadata_2025 huggingface dataset:
The mediating role of lifestyle in the relationship between shift work, obesity and diabetes
Authors: Hulsegge Gerben , Proper Karin I. , Loef Bette , Paagman Heleen , Anema Johannes R. , van Mechelen Willem
Published: March 2021

Purpose

Shift work has been related to obesity and diabetes, but the potential mediating role of lifestyle is yet unknown. Our aim was to investigate this mediating role of physical activity, diet, smoking, and sleep quality in the relationships between shift work, and obesity and diabetes.

Methods

In this cross-sectional study, 3188 shift workers and 6395 non-shift workers participated between 2013 and 2018 in periodical occupational health checks. Weight and height were objectively measured to calculate obesity (BMI ≥ 30 kg/m2). Diabetes status, physical activity, diet, smoking, and sleep quality were assessed using standardized questionnaires. Structural equation models adjusted for relevant confounders were used to analyze the mediating role of lifestyle in the relationships between shift work, and obesity and diabetes.

Results

Shift workers were more often obese (OR: 1.37, 95% CI 1.16–1.61) and reported more often to have diabetes (OR:1.35, 95% CI 1.003–1.11) than non-shift workers. Shift workers had lower physical activity levels, ate fruit and vegetables less often, smoked more often, and had poorer sleep quality (p < 0.05). Mediation analysis revealed that shift workers had a higher odds of obesity (OR: 1.07, 95% CI 1.01–1.15) and diabetes (OR: 1.13, 95% CI 1.02–1.27) mediated by poorer sleep quality. Lower physical activity levels (OR: 1.11, 95% CI 1.05–1.19) and lower intake of fruit and vegetables (OR: 1.04, 95% CI 1.01–1.15) were also mediators in the relationship between shift work and obesity, but not in the relationship between shift work and diabetes (p ≥ 0.05).

Conclusion

These results imply that interventions targeting diet, physical activity and in particular sleep problems specifically developed for shift workers could potentially reduce the adverse health effects of shift work.
Performance determinants, running energetics and spatiotemporal gait parameters during a treadmill ultramarathon
Authors: Howe Christopher C. F. , Swann Nicola , Spendiff Owen , Kosciuk Anna , Pummell Elizabeth K. L. , Moir Hannah J.
Published: March 2021

Purpose

The objective of this study was to investigate the changes in metabolic variables, running energetics and spatiotemporal gait parameters during an 80.5 km treadmill ultramarathon and establish which key predictive variables best determine ultramarathon performance.

Methods

Twelve participants (9 male and 3 female, age 34 ± 7 years, and maximal oxygen uptake ($$\dot{V}$$

V
˙

O2max) 60.4 ± 5.8 ml·kg−1·min−1) completed an 80.5 km time trial on a motorised treadmill in the fastest possible time. Metabolic variables: oxygen consumption ($$\dot{V}$$

V
˙

O2), carbon dioxide production ($$\dot{V}$$

V
˙

CO2) and pulmonary ventilation ($$\dot{V}$$

V
˙

E) were measured via indirect calorimetry every 16.1 km at a controlled speed of 8 km·h−1 and used to calculate respiratory exchange ratio (RER), the energy cost of running (Cr) and fractional utilisation of $$\dot{V}$$

V
˙

O2max (F). Spatiotemporal gait parameters: stride length (SL) and cadence (SPM) were calculated via tri-axial accelerometery.

Results

Trial completion time was 09:00:18 ± 01:14:07 (hh:mm:ss). There were significant increases in $$\dot{V}$$

V
˙

O2, Cr, F, $$\dot{V}$$

V
˙

E and heart rate (HR) (p < 0.01); a significant decrease in RER (p < 0.01) and no change in SL and SPM (p > 0.05) across the measured timepoints. F and Cr accounted for 61% of the variance in elapsed finish time ($$R_{{{\text{adj}}}}^{{2}}$$

R

adj

2

 = 0.607, p < 0.01).

Conclusion

A treadmill ultramarathon elicits significant changes in metabolic variables, running energetics and spatiotemporal gait parameters. With F and Cr explaining 61% of variance in finish time. Therefore, those able to maintain a higher F, while adopting strategies to minimise an increase in Cr may be best placed to maximise ultramarathon performance.
Long-term physical training in adolescent sprint and middle distance swimmers alters the composition of circulating T and NK cells which correlates with soluble ICAM-1 serum concentrations
Authors: Notbohm Hannah L. , Schumann Moritz , Fuhrmann Stefan , Klocke Jan , Theurich Sebastian , Bloch Wilhelm
Published: March 2021

Purpose

It remains unknown how different training intensities and volumes chronically impact circulating lymphocytes and cellular adhesion molecules. First, we aimed to monitor changes in NK and T cells over a training season and relate these to training load. Second, we analyzed effects of training differences between swimmers on these cells. Finally, we examined if changes in lymphocytes were associated with sICAM-1 concentrations.

Methods

We analyzed weekly training volume, training intensity, proportions of T and NK cells and serum sICAM-1 in eight sprint (SS) and seven middle-distance swimmers (MID) at three points over a 16-week training period: at the start (t0), after 7 weeks of increased training load (t7) and after 16 weeks, including 5-day taper (t16).

Results

Training volume of all swimmers was statistically higher and training intensity lower from t0–t7 compared to t7–t16 (p = 0.001). Secondly, training intensity was statistically higher in SS from t0–t7 (p = 0.004) and t7–t16 (p = 0.015), while MID had a statistically higher training volume from t7–t16 (p = 0.04). From t0–t7, NK (p = 0.06) and CD45RA+CD45RO+CD4+ cells (p < 0.001) statistically decreased, while CD45RA−CD45RO+CD4+ cells (p = 0.024) statistically increased. In a subgroup analysis, SS showed statistically larger increases in NK cells from t7–t16 than MID (p = 0.012). Lastly, sICAM-1 concentrations were associated with changes in CD45RA−CDRO+CD4+ cells (r = − 0.656, p = 0.08).

Conclusion

These results indicate that intensified training in swimmers resulted in transient changes in T and NK cells. Further, NK cells are sensitive to high training volumes. Lastly, sICAM-1 concentrations may be associated with the migration and maturation of CD4+ cells in athletes.
Transient elastography correlated to four different histological fibrosis scores in children with liver disease
Authors: Teufel-Schäfer Ulrike , Flechtenmacher Christa , Fichtner Alexander , Hoffmann Georg Friedrich , Schenk Jens Peter , Engelmann Guido
Published: March 2021

Currently, liver histology is the gold standard for the detection of liver fibrosis. In recent years, new methods such as transient elastography (TE) have been introduced into clinical practice, which allow a non-invasive assessment of liver fibrosis. The aim of the present study was to investigate the predictive value of TE for higher grade fibrosis and whether there is any relevance which histologic score is used for matching. For this purpose, we compared TE with 4 different histologic scores in pediatric patients with hepatopathies. Furthermore, we also determined the aspartate aminotransferase-to-platelet ratio (APRI) score, another non-invasive method, to investigate whether it is equally informative. Therefore, liver fibrosis in 75 children was evaluated by liver biopsy, TE and laboratory values. Liver biopsies were evaluated using four common histological scoring systems (Desmet, Metavir, Ishak and Chevalier’s semi-quantitative scoring system). The median age of the patients was 12.3 years. TE showed a good correlation to the degree of fibrosis severity independent of the histological scoring system used. The accuracy of the TE to distinguish between no/minimal fibrosis and severe fibrosis/cirrhosis was good (p = 0.001, AUC-ROCs > 0.81). The optimal cut-off value for the prediction of severe fibrosis was 10.6 kPa. In contrast, the APRI score in our collective showed no correlation to fibrosis.

Conclusion: TE shows a good correlation to the histological findings in children with hepatopathy, independent of the used histological scoring system.

What is Known:• The current gold standard for detecting liver fibrosis is liver biopsy. Novel non-invasive ultrasound-based methods are introduced to clinical diagnostics.• Most histological scores have been developed and evaluated in adult populations and for only one specific liver disease.What is New:• Transient elastography (TE) in children showed a good correlation to fibrosis severity irrespective of the utilized histological scoring system.• The aspartate aminotransferase-to-platelet ratio (APRI) showed no correlation with different stages of liver fibrosis in children.
Submarine lava deltas of the 2018 eruption of Kīlauea volcano
Authors: Soule S. Adam , Zoeller Michael , Parcheta Carolyn
Published: March 2021

Hawaiian and other ocean island lava flows that reach the coastline can deposit significant volumes of lava in submarine deltas. The catastrophic collapse of these deltas represents one of the most significant, but least predictable, volcanic hazards at ocean islands. The volume of lava deposited below sea level in delta-forming eruptions and the mechanisms of delta construction and destruction are rarely documented. Here, we report on bathymetric surveys and ROV observations following the Kīlauea 2018 eruption that, along with a comparison to the deltas formed at Pu‘u ‘Ō‘ō over the past decade, provide new insight into delta formation. Bathymetric differencing reveals that the 2018 deltas contain more than half of the total volume of lava erupted. In addition, we find that the 2018 deltas are comprised largely of coarse-grained volcanic breccias and intact lava flows, which contrast with those at Pu‘u ‘Ō‘ō that contain a large fraction of fine-grained hyaloclastite. We attribute this difference to less efficient fragmentation of the 2018 ‘a‘ā flows leading to fragmentation by collapse rather than hydrovolcanic explosion. We suggest a mechanistic model where the characteristic grain size influences the form and stability of the delta with fine grain size deltas (Pu‘u ‘Ō‘ō) experiencing larger landslides with greater run-out supported by increased pore pressure and with coarse grain size deltas (Kīlauea 2018) experiencing smaller landslides that quickly stop as the pore pressure rapidly dissipates. This difference, if validated for other lava deltas, would provide a means to assess potential delta stability in future eruptions.
A flexible framework for anomaly Detection via dimensionality reduction
Authors: Vafaei Sadr Alireza , Bassett Bruce A. , Kunz M.
Published: March 2021

Anomaly detection is challenging, especially for large datasets in high dimensions. Here, we explore a general anomaly detection framework based on dimensionality reduction and unsupervised clustering. DRAMA is released as a general python package that implements the general framework with a wide range of built-in options. This approach identifies the primary prototypes in the data with anomalies detected by their large distances from the prototypes, either in the latent space or in the original, high-dimensional space. DRAMA is tested on a wide variety of simulated and real datasets, in up to 3000 dimensions, and is found to be robust and highly competitive with commonly used anomaly detection algorithms, especially in high dimensions. The flexibility of the DRAMA framework allows for significant optimization once some examples of anomalies are available, making it ideal for online anomaly detection, active learning, and highly unbalanced datasets. Besides, DRAMA naturally provides clustering of outliers for subsequent analysis.
Multidimensional profiles of learning orientations and school achievement: a person-oriented approach in middle-school students
Authors: Vettori Giulia , Vezzani Claudio , Bigozzi Lucia , Pinto Giuliana
Published: March 2021

A person-oriented approach was applied to the study of early adolescents’ learning orientations to identify different profiles and their association with school achievement. A total of 244 middle-school students (male: 128; female: 116; M-age ± SD = 12.51 ± .93) completed a self-report questionnaire to explore cognitive, metacognitive, and affective dimensions of learning orientations. School achievements were collected in a range of school subjects. Cluster analyses and one-way MANOVA were carried out to verify the existence of profiles. Chi-square tests were used to test the association between profiles of learning orientations and school achievement. The results showed two profiles differently associated with school achievement: students “Dragged by the current” (Profile 1) showed low school achievement across school subjects, meanwhile students “At the helm” (Profile 2) reached excellent school achievement. In promoting middle-school students’ achievement, it is important for teachers to consider students’ profiles of learning orientations.
Industrial biochar systems for atmospheric carbon removal: a review
Authors: Fawzy Samer , Osman Ahmed I. , Yang Haiping , Doran John , Rooney David W.
Published: March 2021

In the context of climate change, there is an urgent need for rapid and efficient methods to capture and sequester carbon from the atmosphere. For instance, production, use and storage of biochar are highly carbon negative, resulting in an estimated sequestration of 0.3–2 Gt CO2 year−1 by 2050. Yet, biochar production requires more knowledge on feedstocks, thermochemical conversion and end applications. Herein, we review the design and development of biochar systems, and we investigate the carbon removal industry. Carbon removal efforts are currently promoted via the voluntary market. The major commercialized technologies for offering atmospheric carbon removal are forestation, direct air carbon capture utilization and storage, soil carbon sequestration, wooden building elements and biochar, with corresponding fees ranging from 10 to 895 GBP (British pounds) per ton CO2. Biochar fees range from 52 to 131 GBP per ton CO2, which indicates that biochar production is a realistic strategy that can be deployed at large scale. Carbon removal services via biochar are currently offered through robust marketplaces that require extensive certification, verification and monitoring, which adds an element of credibility and authenticity. Biochar eligibility is highly dependent on the type of feedstock utilized and processing conditions employed. Process optimization is imperative to produce an end product that meets application-specific requirements, environmental regulations and achieve ultimate stability for carbon sequestration purposes.
Brownian Motion at the Speed of Light: A New Lorentz Invariant Family of Processes
Authors: Serva Maurizio
Published: March 2021

We consider here a new family of processes which describe particles which only can move at the speed of light c in the ordinary 3D physical space. The velocity, which randomly changes direction, can be represented as a point on the surface of a sphere of radius c and its trajectories only may connect points of this variety. A process can be constructed both by considering jumps from one point to another (velocity changes discontinuously) and by continuous velocity trajectories on the surface. We recently proposed to follow this second strategy assuming that the velocity is described by a Wiener process (which is isotropic only in the ’rest frame’) on the surface of the sphere. Using both Ito calculus and Lorentz boost rules, we succeed here in characterizing the entire Lorentz-invariant family of processes. Moreover, we highlight and describe the short-term ballistic behavior versus the long-term diffusive behavior of the particles in the 3D physical space.
Path planning for endovascular catheterization under curvature constraints via two-phase searching approach
Authors: Li Zhen , Dankelman Jenny , De Momi Elena
Published: March 2021

Purpose

Planning a safe path for flexible catheters is one of the major challenges of endovascular catheterization. State-of-the-art methods rarely consider the catheter curvature constraint and reduced computational time of path planning which guarantees the possibility to re-plan the path during the actual operation.

Methods

In this manuscript, we propose a fast two-phase path planning approach under the robot curvature constraint. Firstly, the vascular structure is extracted and represented by vascular centerlines and corresponding vascular radii. Then, the path is searched along the vascular centerline using breadth first search (BFS) strategy and locally optimized via the genetic algorithm (GA) to satisfy the robot curvature constraint. This approach (BFS-GA) is able to respect the robot curvature constraint while keeping it close to the centerlines as much as possible. We can also reduce the optimization search space and perform parallel optimization to shorten the computational time.

Results

We demonstrate the method’s high efficiency in two-dimensional and three-dimensional space scenarios. The results showed the planner’s ability to satisfy the robot curvature constraint while keeping low computational time cost compared with sampling-based methods. Path replanning in femoral arteries can reach an updating frequency at $$6.4\pm 2.3$$

6.4
±
2.3

Hz.

Conclusion

The presented work is suited for surgical procedures demanding satisfying curvature constraints while optimizing specified criteria. It is also applicable for curvature constrained robots in narrow passages.
Psychological Aspects to Consider in Breast Cancer Diagnosis and Treatment
Authors: Dinapoli Loredana , Colloca Giuseppe , Di Capua Beatrice , Valentini Vincenzo
Published: March 2021

Purpose of Review

Breast cancer (BC) is the most common cancer diagnosed in women in the West World. Coping with cancer is cause of extreme stress for patients and their family. The purpose of this review is to evaluate possible approaches to follow to control those situations that can impact on quality of life (QoL) and compliance to treatments.

Recent Findings

Anxiety, distress, depression, and posttraumatic stress disorder are the most frequent psychological disorders in BC patients. Cognitive disorders and sexual dysfunction can also be important in affecting QoL both in younger and older patients. Younger and older patients show different characteristics of these disorders and different strategies of managing them.

Several psychotherapeutic and supportive approaches have proven effective in managing psychological disorders in BC patients. Every BC patient should be supported with these techniques during her entire oncological history, in order to increase QoL and compliance to treatments.
Native and IgE-primed rat peritoneal mast cells exert pro-inflammatory activity and migrate in response to yeast zymosan upon Dectin-1 engagement
Authors: Żelechowska Paulina , Brzezińska-Błaszczyk Ewa , Różalska Sylwia , Agier Justyna , Kozłowska Elżbieta
Published: March 2021

Mast cells (MCs) play an essential role in host defense, primarily because of their location, their ability to pathogen destruction via several mechanisms, and the pattern recognition receptors they express. Even though most data is available regarding MC activation by various bacteria- or virus-derived molecules, those cells’ activity in response to constituents associated with fungi is not recognized enough. Our research aimed to address whether Saccharomyces cerevisiae-derived zymosan, i.e., β-(1,3)-glucan containing mannan particles, impacts MC activity aspects. Overall, the obtained results indicate that zymosan has the potential to elicit a pro-inflammatory response of rat peritoneal MCs. For the first time ever, we provided evidence that zymosan induces fully mature MC migration, even in the absence of extracellular matrix (ECM) proteins. Moreover, the zymosan-induced migratory response of MCs is almost entirely a result of directional migration, i.e., chemotaxis. We found that zymosan stimulates MCs to degranulate and generate lipid mediators (cysLTs), cytokines (IFN-α, IFN-β, IFN-γ, GM-CSF, TNF), and chemokine (CCL2). Zymosan also upregulated mRNA transcripts for several cytokines/chemokines with pro-inflammatory/immunoregulatory activity. Moreover, we documented that zymosan activates MCs to produce reactive oxygen species (ROS). Lastly, we established that the zymosan-induced MC response is mediated through activation of the Dectin-1 receptor. In general, our results strongly support the notion that MCs contribute to innate antifungal immunity and bring us closer to elucidate their role in host-pathogenic fungi interactions. Besides, provided findings on IgE-sensitized MCs appear to indicate that exposure to fungal zymosan could affect the severity of IgE-dependent disorders, including allergic ones.
Population structure of Laurus nobilis L. in Central Italian forests: evidence for its ongoing expansion
Authors: Alessi Nicola , Wellstein Camilla , Spada Francesco , Zerbe Stefan
Published: March 2021

During the last decades, an ongoing spread of broad-leaved evergreen laurophyllous species has been reported for forests of Southern Europe. Several factors were suggested as the main drivers of the phenomenon, namely global warming, land-use change, evolutionary history, and increase in atmospheric CO2. Among laurophylls, Laurus nobilis L. is considered one of the most prominent from the morphological, evolutionary, and ecological point of view. We studied the population structure of L. nobilis in Central Italy in its natural habitat to investigate its regeneration and potential expansion along with the influence biotic and abiotic factors. To define types of population structures, we collected proportions of six growth classes of L. nobilis in 16 sites. We obtained three types of population structure, i.e., (1) stable, (2) dynamic, and (3) regressive. The first two types are the most frequent, suggesting a potential increase of L. nobilis abundance within forests of Central Italy. The regressive population type occurs mainly in sites with heavy ungulate impact. High propagule pressure along with shaded and moist environmental conditions favor L. nobilis regeneration. Accordingly, we found evidence of a recent L. nobilis spread in Central Italian forests. We suggest the increase of forest cover and age, due to the abandonment of traditional rural practices, as key factors for the regeneration of this apparently late-successional laurophyll. In conclusion, the recent expansion of L. nobilis that we observed in the Italian forest stands can therefore be ascribed to a process of natural recover of a potential niche following land-use change.
Retinae of Anencephalic Fetuses: Quantitative Analysis and Comparison with Fetuses Without any Malformations
Authors: Shah Garima , Dwivedi Daisy , Chander Bal
Published: March 2021

Anencephaly is a common congenital malformation characterised by absence of a major portion of the brain. The sequence of brain degeneration starts around 20 days post fertilization which overlaps with the appearance of optic grooves from the forebrain. A number of ocular malformations associated with anencephaly have been reported. Based on the assumption that eyes, which are derived from the brain, are likely to be abnormal since the organ of origin undergoes degeneration, studies have been carried out on anencephalic retinae. Some of the results have indicated that retinae of anencephalic fetuses are abnormal with absence or diminished presence of ganglion cell layer compared to the fetuses without such a brain malformation. We undertook the present study with an aim to objectively and quantitatively evaluate retinal thickness and numbers of ganglion cell in anencephalic fetuses and fetuses without any malformations. Six anencephalic and six fetuses without malformations were included, all of them from 18 to 21 weeks of gestation. Histopathological evaluation of retinae was done and findings compared. We did not find any atrophy or reduced number of ganglion layer cells in anencephalic fetuses. This evaluation assumes importance since retinae from anencephalic fetuses can be a potential source for retinal tissue or stem cell transplant. Moreover, the contention that normal brain development is essential for retinal development appears to be invalid.
A modified NK algorithm based on BP neural network and DEMATEL for evolution path optimization of urban innovation ecosystem
Authors: Liu Ruijian , Tang Fangcheng , Wang Yuhan , Zheng Shaofang
Published: March 2021

In the new era, the key measure to accelerate the construction of smart city, so as to promote the modernization of urban governance system and governance capacity, is to establish a good urban innovation ecosystem, and guide its continuous evolution to the direction of the highest efficiency and the best performance. Focusing on solving the practical problem of “how the urban innovation ecosystem evolves”, this paper develops a NK algorithm using BP neural network and DEMATEL method. First, through literature research, constructing the urban innovation ecosystem including five subsystems of innovation talents, innovation subjects, innovation resources, innovation environment and innovation network. Then, taking Beijing as an example, the weights and the number of epistatic relationships of each subsystem in its innovation ecosystem are calculated by BP neural network and DEMATEL method, and the NK model is modified; on this basis, the fitness values corresponding to different states of the system are calculated using MATLAB software, and the optimal evolution path of Beijing innovation ecosystem is determined through the comparison of 100,000 simulation results. The results show that the optimal evolution path of Beijing's innovation ecosystem is to create a favorable environment and culture for innovation first; then increase the input of innovation resources; and then promote the development of innovation network assets; on this basis, cultivate, attract and retain innovative talents; and finally strengthen the construction of innovation subjects.
inGAP-Family: Accurate Detection of Meiotic Recombination Loci and Causal Mutations by Filtering Out Artificial Variants due to Genome Complexities
Authors: Lian Qichao , Chen Yamao , Chang Fang , Fu Ying , Qi Ji
Published: March 2021

Accurately identifying DNA polymorphisms can bridge the gap between phenotypes and genotypes and is essential for molecular marker assisted genetic studies. Genome complexities, including large-scale structural variations, bring great challenges to bioinformatic analysis for obtaining high-confidence genomic variants, as sequence differences between non-allelic loci of two or more genomes can be misinterpreted as polymorphisms. It is important to correctly filter out artificial variants to avoid false genotyping or estimation of allele frequencies. Here, we present an efficient and effective framework, inGAP-family, to discover, filter, and visualize DNA polymorphisms and structural variants (SVs) from alignment of short reads. Applying this method to polymorphism detection on real datasets shows that elimination of artificial variants greatly facilitates the precise identification of meiotic recombination points as well as causal mutations in mutant genomes or quantitative trait loci. In addition, inGAP-family provides a user-friendly graphical interface for detecting polymorphisms and SVs, further evaluating predicted variants and identifying mutations related to genotypes. It is accessible at https://sourceforge.net/projects/ingap-family/.
The Economisation of Climate Change
Authors: Skovgaard Jakob
Published: March 2021

The effort to address climate change cuts across a wide range of non-environmental actors and policy areas, including international economic institutions such as the Group of Twenty (G20), International Monetary Fund (IMF), and the Organisation for Economic Co-operation and Development (OECD). These institutions do not tend to address climate change so much as an environmental issue, but as an economic one, a dynamic referred to as 'economisation'. Such economisation can have profound consequences for how environmental problems are addressed. This book explores how the G20, IMF, and OECD have addressed climate finance and fossil fuel subsidies, what factors have shaped their specific approaches, and the consequences of this economisation of climate change. Focusing on the international level, it is a valuable resource for graduate students, researchers, and policymakers in the fields of politics, political economy and environmental policy. This title is also available as Open Access.
Rethinking Research Sites as Wilderness Activity Sites
Authors: Peixotto Becca , Klehm Carla , Eifling Kurt P.
Published: March 2021

Field research requires careful preparation so as to protect the integrity of archaeological studies and ensure the health and wellness of our students and field crews. In this special issue, we hope to lay a foundation for securing health and wellness as elements of the ethical practice of archaeology fieldwork through discussions of common hazards and tools to prevent, prepare for, and address safety incidents in the field. Even as archaeology and other field sciences grapple with serious safety concerns such as sexual harassment and mental health, it can be tempting to view field sites as extensions of the classroom or office. But field research can be a high-risk endeavor where we are exposed to a range of hazards not typically encountered in a traditional learning or work environment. We reach across disciplinary boundaries toward outdoor leadership and backcountry medicine to introduce the concept of wilderness context to describe the remote—and not-so-remote—locations and conditions common to archaeology field research. These are places where small or unanticipated problems can quickly become serious incidents. By rethinking research sites as wilderness activity sites, we highlight how methodical preparation can help us craft more robust and ethical health and safety practices for all members of our teams.
Ice thickness and volume of the Renland Ice Cap, East Greenland
Authors: Koldtoft Iben , Grinsted Aslak , Vinther Bo M. , Hvidberg Christine S.
Published: March 2021

To assess the amount of ice volume stored in glaciers or ice caps, a method to estimate ice thickness distribution is required for glaciers where no direct observations are available. In this study, we use an existing inverse method to estimate the bedrock topography and ice thickness of the Renland Ice Cap, East Greenland, using satellite-based observations of the surface topography. The inverse approach involves a procedure in which an ice dynamical model is used to build-up an ice cap in steady state with climate forcing from a regional climate model, and the bedrock is iteratively adjusted until the modelled and observed surface topography match. We validate our model results against information from airborne radar data and satellite observed surface velocity, and we find that the inferred ice thickness and thereby the stored total volume of the ice cap is sensitive to the assumed ice softness and basal slipperiness. The best basal model parameters for the Renland Ice Cap are determined and the best estimated total ice volume of 384 km3 is found. The Renland Ice Cap is particularly interesting because of its location at a high elevation plateau and hence assumed low sensitivity to climate change.
Success rate of type 1 tympanoplasty: a comparative study
Authors: Odat H , Alali M , Kanaan Y , Al-Qudah M
Published: March 2021

Objectives

This study aimed to compare graft take rate after tympanoplasty between adults and paediatric patients, cartilage and fascia grafts, and overlay and underlay techniques.

Methods

Data were analysed in groups according to the technique (underlay vs overlay), age (paediatric patients vs adults) and graft (cartilage vs temporalis fascia). The main outcome measures were full graft take and the incidence of complications.

Results

A total of 198 patients (208 ears) were included. Overall, full graft take was achieved in 200 ears (96 per cent). The success rate was higher in adults compared with paediatric patients (97.5 per cent vs 92.25, respectively) but the difference was insignificant. Similarly, higher but insignificant graft take rate was found in the cartilage group compared with fascia group (98.6 per cent vs 94.9 per cent, respectively).

Conclusion

All cases of overlay tympanoplasty had full graft take (success rate 100 per cent). In the underlay group, successful graft take was achieved in 154 cases (95 per cent). This difference was statistically insignificant.
Toxoplasma gondii in mollusks and cold-blooded animals: a systematic review
Authors: Nayeri Tooran , Sarvi Shahabeddin , Daryani Ahmad
Published: March 2021

Toxoplasma gondii (T. gondii) is known for its ability to infect warm-blooded vertebrates. Although T. gondii does not appear to parasitize cold-blooded animals, the occurrence of T. gondii infection in marine mammals raises concerns that cold-blooded animals (frogs, toad, turtles, crocodiles, snakes, and fish) and shellfish are potential sources of T. gondii. Therefore, this systematic review aimed to determine the prevalence of T. gondii in mollusks and cold-blooded animals worldwide. We searched PubMed, ScienceDirect, ProQuest, Scopus, and Web of Science from inception to 1 August 2020 for eligible papers in the English language and identified 26 articles that reported the prevalence of T. gondii in mollusks and cold-blooded animals. These articles were subsequently reviewed and data extracted using a standard form. In total, 26 studies [involving 9 cross-sectional studies including 2988 samples of cold-blooded animals (129 positive cases for T. gondii) and 18 cross-sectional studies entailing 13 447 samples of shellfish (692 positive cases for T. gondii)] were included in this study. Although this study showed that shellfish and cold-blooded animals could be potential sources of T. gondii for humans and other hosts that feed on them, further investigations are recommended to determine the prevalence of T. gondii in shellfish and cold-blooded animals.
The Relevance of Job-Related Concessions for Unemployment Duration Among Recipients of Means-Tested Benefits in Germany
Authors: CHRISTOPH BERNHARD , LIETZMANN TORSTEN
Published: March 2021

Unemployment strongly influences a person’s economic resources and life chances. Especially for unemployed individuals who have to rely on means-tested benefits, episodes of unemployment often go along with substantial material restrictions. Therefore, from a policy perspective, measures or regulations that might shorten unemployment episodes and reduce overall unemployment are particularly important.

In this paper, we analyse whether concessions regarding the characteristics of the job searched for influence an individual’s unemployment duration. In doing so, we focus on a particular aspect of availability requirements in Germany. This is the fact that for unemployed recipients of means-tested benefits almost all types of jobs count as suitable employment and, therefore, recipients are obliged to make job-related concessions if offered a job requiring such concessions.

The results indicate that there is no positive effect of making concessions regarding qualification requirements or status on employment chances. In contrast, there are positive effects of wage concessions. However, searching for a job in a different occupation (that does not necessarily imply a concession) has a comparable, positive effect on finding employment. Thus, it appears that being generally flexible regarding one’s future occupation might be at least as important for employment chances as making concessions.
Understanding unmet aged care need and care inequalities among older Australians
Authors: Hill Trish
Published: March 2021

In Australia, numerous reviews and inquiries have documented concerns about inadequate access to, and the quality of, aged care. Despite those concerns, research is yet to appraise fully how care needs are assessed, prioritised, and met or left unmet. This paper asks two interrelated questions: (1) How should we conceptualise and measure unmet care need and care inequalities among older people? (2) What are the policy parameters for assessing needs, prioritising access to support and monitoring quality in aged care in Australia? Key insights from academic literature are used to critically review Australian policy documents describing rights, assessments, prioritisation, quality standards and performance indicators for the aged care sector. Using the concepts of care inequalities and care poverty, the paper develops a framework for understanding and measuring needs and unmet needs in aged care, and for encompassing fundamental and valued aspects of life for older people, their carers and their care network. The paper argues that the concept of care poverty opens the space to discuss what level of unmet need and inequality in access to aged care in any society may be considered intolerable.
Lie group based nonlinear state errors for MEMS-IMU/GNSS/magnetometer integrated navigation
Authors: Cui Jiarui , Wang Maosong , Wu Wenqi , He Xiaofeng
Published: March 2021

In the integrated navigation system using extended Kalman filter (EKF), the state error conventionally uses linear approximation to tackle the commonly nonlinear problem. However, this error definition can diverge the filter in some adverse situations due to significant distortion of the linear approximation. By contrast, the nonlinear state error defined in the Lie group satisfies the autonomous equation, which thus has distinctively better convergence property. This work proposes a novel strapdown inertial navigation system (SINS) nonlinear state error defined in the Lie group and derives the SINS equations of the Lie group EKF (LG-EKF) for the MIMU/GNSS/magnetometer integrated navigation system. The corresponding measurement equations are also derived. A land vehicle field test has been conducted to evaluate the performance of EKF, ST-EKF (state transformation extended Kalman filter) and LG-EKF, which verifies LG-EKF's superior estimation accuracy of the heading angle as well as the other two horizontal angles (pitch and roll). The LG-EKF proposed in this paper is unlimited in the choice of sensors, which means it can be applied with both high-end and low-end inertial sensors.
Expression of anaphoric subjects in Vera'a: Functional and structural factors in the choice between pronoun and zero
Authors: Schnell Stefan , Barth Danielle
Published: March 2021

The choice between a pronoun and zero anaphor for the expression of third-person subjects is examined in a corpus of Vera'a (Oceanic). While predominantly expressed by a pronoun, subjects are found to permit zero form with referents that have low anaphoric distance. Within this context, zero is found to be preferred with a subset of verbal predicates that take a specific tense-aspect-mood-polarity (TAMP) marker that historically retains subject agreement. The strong preference for pronouns is related to the clitic behavior of adjacent TAMP morphology and the rudimentarity of agreement. Animacy and number also bear on subject variation. Effects of clause-combining and the use of connectives do not align with findings from studies of the same choice in other languages. Our findings underscore the prominent role of purely structural over functional motivations for the choice of pronouns over zero.
The social embedding of a syntactic alternation: Variable particle placement in Ontario English
Authors: Röthlisberger Melanie , Tagliamonte Sali A.
Published: March 2021

The present work investigates the effects of social constraints on word order variation in particle placement in Ontario English, Canada. While previous research has documented numerous linguistic factors conditioning the choice of variant, social correlates have so far remained unexplored. To address this gap, we analyze 6,047 variable phrasal verbs from the vernacular speech of six communities in Ontario. These data were coded for length of the direct object, verb semantics, community, and the individual's education, gender, age, and occupation. Our analyses confirm previous findings that variation in particle placement is predominantly determined by direct object length. However, we also expose significant social and geographic factors, and importantly an effect of age, with younger speakers using the joined variant more than older speakers. Further analysis confirms that the latter effect is consistent across communities, indicating a change in progress, possibly due to ongoing grammaticalization of particles in the verb phrase.
Increases in oxygen saturation following discharge from Fontan palliation – an indicator of resolution of pulmonary arteriovenous malformations?
Authors: Van Galder Hannah , Schaal Amy M. , Feng Mingen , Pan Amy Y. , Frommelt Michele A. , Ginde Salil , Spearman Andrew D.
Published: March 2021

Background:

Pulmonary arteriovenous malformations in single ventricle congenital heart disease are poorly understood. Previous studies investigating pulmonary arteriovenous malformations predominantly focus on patients with heterotaxy syndrome and interrupted inferior caval vein. It is unknown if development and resolution of pulmonary arteriovenous malformations are similar for patients with and without heterotaxy syndrome.

Methods:

In this retrospective single-institution study, we identified patients with a history of single ventricle congenital heart disease and Fontan palliation. We then matched patients with heterotaxy syndrome (intact and interrupted inferior caval vein) and non-heterotaxy hypoplastic left heart syndrome. To compare development of pulmonary arteriovenous malformations, we identified the frequency of positive diagnoses pre-Fontan. To compare resolution of pulmonary arteriovenous malformations, we recorded oxygen saturation changes for 12 months following Fontan.

Results:

A total of 124 patients were included. Patients with heterotaxy and interrupted inferior caval vein were more likely to have a pre-Fontan contrast echocardiogram performed (p < 0.01) and more likely to be diagnosed with pulmonary arteriovenous malformations pre-Fontan (p < 0.01). There was no difference in oxygen saturation prior to Fontan, yet all patient groups had increased their oxygen saturations in the first year after Fontan discharge.

Conclusions:

Pulmonary arteriovenous malformations are variably diagnosed prior to Fontan palliation; however, all study groups had increased oxygen saturations after Fontan discharge, potentially indicating resolution of pulmonary arteriovenous malformations in all groups. The prevalence of pulmonary arteriovenous malformations pre-Fontan is likely underestimated. A quantitative, systematic approach to diagnosis and follow-up of pulmonary arteriovenous malformations is needed to better understand susceptibility and pathophysiology.
First-Principles Calculation of the Evaporation Field and Roll-up Effect of M (M = Fe, Cu, Si, and Mn) on the Fe (001) and Fe Step Structure
Authors: Ohnuma Toshiharu
Published: March 2021

First-principles calculations were performed on the evaporation field of Fe, Cu, Mn, and Si in Fe (001) and on the evaporation field and roll-up effect of Fe, Cu, and Mn in the Fe (001) step structure. The larger the evaporation barrier energy tendency, at an electric field of 0 V/nm (absorption energy), the larger was the evaporation field. Electric field evaporation calculation results indicate that the order in which the electric field is easily evaporated is Mn > Cu > Fe > Si. The tendency that Mn and Cu evaporate more easily than does Fe and that the evaporation of Si is less probable is consistent with the experiment of a dilute element in steel. In the Fe (001) step structure, when the electric field is low, the roll-up effect where the evaporated atoms move on the step is large, and when the electric field is large, the roll-up effect is small. The roll-up effect of Cu was almost the same as that of Fe, and the roll-up effect of Mn was small because the chemical bond between Mn and Fe was weak.
Differences in African banking systems: causes and consequences
Authors: Mutarindwa Samuel , Schäfer Dorothea , Stephan Andreas
Published: March 2021

This paper links banking system development to the colonial and legal history of African countries. Based on a sample of 40 African countries from 2000 to 2018, our empirical findings show a significant dependence of current financial institutions on the inherited legal origin and the colonization type. Findings also reveal that current financial legal institutions are not major determinants of banking system development, and that institutional development and governance quality are more important. A high share of government spending relative to GDP also positively affects banking system development in African countries.
GKEEP: An Enhanced Graph‐Based Keyword Extractor With Error‐Feedback Propagation for Geoscience Reports
Authors: Qiu Qinjun , Xie Zhong , Xie Hong , Wang Bin
Published: March 2021

As the amount of published geoscience literature grows, reading and summarizing texts of large collections has become a challenging task. Publication keywords can be considered basic components of knowledge structure representations and have been used to reveal knowledge concerning research domains. In contrast to data used in other research domains, the works on textual geoscience data that entail keyword extraction are limited. In this paper, we propose an unsupervised algorithm, the graph‐based keyword extractor with error‐feedback propagation (GKEEP), that enhances graph‐based keyword extraction approaches by using an error‐feedback mechanism similar to the concept of backpropagation. The proposed approach comprises the following steps. A preprocessed document is used as the input of the proposed model and is represented as a weighted undirected graph, where the vertices represent words and the edges represent the cooccurrence relationship between the words constrained by a window size. Subsequently, its nodes are ranked by their importance scores calculated by a graph‐based ranking algorithm. Consequently, all the words have their own scores, and they are used to compute the scores of keyword candidates. Subsequently, the Word2Vec method is applied to recalculate the scores of keyword candidates and rank the keyword candidates to select the final keyword. It also utilizes error feedback to boost the rankings of the most salient terms that would otherwise be deemed less important. With empirical experiments on two real data sets (including our newly built data set), the proposed GKEEP model outperforms state‐of‐the‐art unsupervised models and the existing graph‐based ranking models. The proposed method can effectively reflect intrinsic keyword semantics and interrelationships.
Atlantic‐Origin Cold Saline Water Intrusion and Shoaling of the Nutricline in the Pacific Arctic
Authors: Jung Jinyoung , Cho Kyoung‐Ho , Park Taewook , Yoshizawa Eri , Lee Youngju , Yang Eun Jin , Gal Jong‐Ku , Ha Sun‐Yong , Kim Soobin , Kang Sung‐Ho , Grebmeier Jacqueline M.
Published: March 2021

Atlantic‐origin cold saline water has previously not been considered an important contributor to the nutrient supply in the Pacific Arctic due to the effective insulation by the overlying Pacific‐origin waters that separate the surface mixed layer from the deeper Atlantic Water. Based on hydrographic observations in the northwestern Chukchi Sea from 2015 to 2017, we demonstrate that the intrusion of Atlantic‐origin cold saline water into the halocline boundary between Pacific and Atlantic‐origin waters in 2017 lifted Pacific‐origin nutrients up to the surface layer. We find that the cyclonic atmospheric circulation in 2017 was considerably strengthened, leading to lateral intrusions of two bodies of cold halocline water from the Eurasian marginal seas into the northwestern Chukchi Sea. Our results reveal that the intrusions of cold halocline waters caused unprecedented shoaling of the nutricline and anomalously high surface phytoplankton blooms in typically highly oligotrophic surface waters in the region during summer.