bluuebunny/crossref_metadata_2025 huggingface dataset:
Inclusión educativa en tiempos de COVID-19: Uso de redes sociales en personas con discapacidad intelectual
Authors: Bonilla-del-Río Mónica , Sánchez-Calero Mª Luisa
Published: September 2021

Los procesos de enseñanza-aprendizaje se han transformado de manera repentina e irremediable debido a las consecuencias provocadas por la COVID-19. Tanto los educadores como el alumnado se han visto forzados a adaptarse a las imprevistas necesidades contextuales y pedagógicas, recurriendo a los dispositivos y entornos virtuales para desarrollar sus prácticas didácticas. Estos retos en ocasiones han provocado ciertas dificultades, pero también nuevas oportunidades de comunicación y de acceso a la información y el conocimiento. En la presente investigación se analizan los usos de las plataformas digitales por parte tanto de los jóvenes con discapacidad como de los especialistas y familias de un centro de la Comunidad de Madrid para hacer frente a esta nueva realidad. Para ello, se ha aplicado un cuestionario y se han realizado entrevistas semiestructuradas a los diferentes agentes educativos. Los resultados inciden en los beneficios y barreras que se han encontrado durante el proceso de adaptación a la modalidad virtual impuesta de forma abrupta por la pandemia, así como en los cambios que el confinamiento ha supuesto en el uso que hacen de los dispositivos y plataformas digitales. Las conclusiones apuntan a que hoy más que nunca la inclusión digital implica la inclusión social y educativa. Sin embargo, si no se apuesta por ella estaríamos ante nuevas formas de exclusión que se pronuncian en este contexto de emergencia sanitaria y distanciamiento social. Por tanto, la educación mediática se establece como un factor clave para evitar que se incremente la brecha digital en este colectivo.
Open Media Forensics Challenge (OpenMFC) 2020-2021 :
Authors: Guan Haiying , Lee Yooyoung , Diduch Lukas , Zhang Jesse G , Ghorbanian Ilia , Kheyrkhah Timothee , Fontana Peter C , Fiscus Jon , Filliben James
Published: September 2021

This document describes the online leaderboard public evaluation program, Open Media Forensics Challenge (OpenMFC) 2021-2022. In the report, first, the introduction, objectives, challenges, contributions, and achievements of the evaluation program are covered and discussed in the Section 1. Second, the evaluation website, tasks, datasets, and the leaderboard interface are described in the Section 2. The participants system performance results are also presented in this section. Third, the community engagements, findings, and public participants difficulties are summarized in the Section 3. Then, two new studies for the next year evaluation, OpenMFC 2021-2022, are introduced in the same section. After that, the solutions to help public participants and the OpenMFC 2021-2022 work plan are proposed in the Section 4. Finally, the potential impacts are predicated in the Section 5. In the OpenMFC 2020-2021 evaluation, 56 participants registered the program, and 194 public researchers worldwide received MFC datasets. Since 2016, NIST has released MFC dataset to more than 500 individuals, 200 organizations, from 26 countries and regions worldwide.
Sætningskompleksitet i dansk
Authors: Christiansen Mads
Published: September 2021

This article gives an introduction to linguistic complexity and investigates the complexity of sentences in Danish from a diachronic perspective. By taking a recursion-based approach to the phenomenon, it can be shown that in the old part of the corpus (eighteenth/ nineteenth century) sentences are more complex than in the new part (twentieth/twentyfirst century). For instance, the older texts are found to contain more clauses per sentence, more clause complexes and more subordinate clauses of a higher degree of dependency than the contemporary texts. The observation that a similar development occurs in Swedish and German should be considered when trying to explain the process of complexity reduction.
Islandsk sprog og dansk tunge
Authors: Hauksdóttir Auður
Published: September 2021

The Icelandic language and medieval literature played an important role in the development of Danish national identity. Icelandic manuscripts served as a key source for the writing of Denmark’s earliest history and attracted widespread interest among Danish scholars.

Growing nationalist sentiment was increasingly directed at the mother tongue, which was considered a major cornerstone of national identity. Knowledge of Icelandic could be of key importance for researching the Danish language, and for interpreting the meaning of older writings.

Languages that had a long tradition of writing and prestigious literature were highly respected, and it was significant to find an unbroken connection between the contemporary and original language. In this respect, the Icelandic language had characteristics that Danish no longer had.

Interest of Danes in Icelandic language and literature, together with the important role they were accorded in the age of Romanticism, meant a great deal to Icelanders. Apart from creating job opportunities and income in Copenhagen, these conditions fuelled their pride as Icelanders and boosted awareness of the significance of language for Icelandic nationality and culture. As a result, interest on the part of Danes in Icelandic language and culture contributed to the growth and development of both Icelandic and Danish.
Fortællerens fødsel ud af snestormen
Authors: Ehlers Dam Anders
Published: September 2021

In this article I analyze ‘Kirstens sidste Rejse’ [Kirsten’s Last Journey], one of Johannes V. Jensen’s stories from Himmerland, drawing on both the original version of the text published in 1901, and the version included in 1904 in Nye Himmerlandshistorier [New Stories from Himmerland]. At first sight, the story is realistic account of two men transporting a coffin with the corpse of an old woman from Aalborg to her home village in Himmerland where she is to be buried, and the violent snowstorm in which they are caught on the way. By the time they finally reach their destination, Christen Sørensen, who has been driving the horse-drawn carriage, has undergone a profound change. Earlier a silent person, he now recounts endlessly, with the same mechanical voice, the journey with the dead woman. In this article, I offer a reading of the story from the perspective of Maurice Blanchot’s literary theory, arguing that Johannes V. Jensen’s text can be read as an allegory of the becoming of the literary narration and its relation to the experience of death and nothingness.
Innovation projects in the area of formal, non-formal and informal education for sustainable development
Authors: Sokolova Liudmila , Ermakov Dmitrii Sergeevich
Published: September 2021

Education for sustainable development (ESD) has been one of the priority vectors in the activity of international organizations since 1990s. The UNESCO-Japan Prize on Education for sustainable development has been awarded since 2015. This article is dedicated to the analysis of innovation projects in the area of formal, non-formal and informal education for sustainable development that have received this award over the period from 2015-= to 2019. The subject of this research is the content of projects and programs of the winner countries in the corresponding areas of ESD. The systemic approach demonstrates that the initiatives that equally affect social, economic and environmental aspects of ESD and lead to positive individual and societal changes become the winners. It is determined that the share of projects and programs in the area of formal and informal education is insignificant  (7 and 13%, respectively). Despite a considerable number for informal ESD (33%), most of the initiatives (47%) are of complex nature. The advanced experience of the award-winning countries complement the existing representations on the opportunities of studying the questions of sustainable development in the area of non-formal and informal education, as well as indicates the benefits of continuous ESD throughout life. For the implementation of ESD, the authors employ general institutional approach that reveals the strategy of activity of the educational institutions oriented towards sustainable development, which results in subsequent “ESD-transformation” of the traditional model of education.
Binarity of the role of higher inclusive education in development of socio-professional subjectivity
Authors: Mal'tseva Tat'yana Evgen'evna
Published: September 2021

The subject of this research is the process of formation of socio-professional subjectivity of persons with socio-functional dissimilarities, among whom are people with impairments, pensioners, military, prisoners, and released from prison. The object of this research is the higher inclusive education viewed through prism of modernization of the system of higher education, being a crucial organizational-substantive and goal-directed aspect, within which inclusive education plays not only an educational-enlightening role such as formation of professional competencies, but also in the specifically arranged inclusive field ensures formation and development of their socio-professional subjectivity, changing their assertions, needs, and motives from personal-passive to socially significant. The conclusion is made that socio-psychological adaptation and increase of the role and status of people with socio-functional dissimilarities implies socio-professional development of subjectivity as a certain system organization of consciousness, human psyche that includes cognitive, emotional-willed, and activity components inherent to a person as a subject of activity. The author underlines the need for functional model that would be aimed at solution of personal issues, as well as increase of the professional role and social status. This approach suggests binary role of inclusive professionalization.
Closed range weighted composition operators between L^{p}-spaces
Authors: Lo Ching-on , Loh Anthony Wai-keung
Published: September 2021

We characterize the closedness of ranges of weighted composition operators between \(L^p\)-spaces, where \(1 \leq p \leq \infty\). When the \(L^p\)-spaces are weighted sequence spaces, several corollaries about this class of operators are also deduced.
Running with Robots
Authors: Toppo Greg , Tracy Jim
Published: September 2021

How the technological changes that are reshaping the future of work will transform the American high school as well.

What will high school education look like in twenty years? High school students are educated today to take their places in a knowledge economy. But the knowledge economy, based on the assumption that information is a scarce and precious commodity, is giving way to an economy in which information is ubiquitous, digital, and machine-generated. In Running with Robots, Greg Toppo and Jim Tracy show how the technological advances that are already changing the world of work will transform the American high school as well.

Toppo and Tracy—a journalist and an education leader, respectively—look at developments in artificial intelligence and other fields that promise to bring us not only driverless cars but doctorless patients, lawyerless clients, and possibly even teacherless students. They visit schools from New York City to Iowa that have begun preparing for this new world. Toppo and Tracy intersperse these reports from the present with bulletins from the future, telling the story of a high school principal who, Rip Van Winkle–style, sleeps for twenty years and, upon awakening in 2040, can hardly believe his eyes: the principal's amazingly efficient assistant is a robot, calculation is outsourced to computers, and students, grouped by competence and not grade level, focus on the conceptual. The lesson to be learned from both the present and the book's thought-experiment future: human and robotic skillsets are complementary, not in competition. We can run with robots, not against them.
Phosphorylation of luminal region of the SUN-domain protein Mps3 promotes nuclear envelope localization during meiosis
Authors: Prasada Rao Hanumanthu BD , Sato Takeshi , Challa Kiran , Fujita Yurika , Shinohara Miki , Shinohara Akira
Published: September 2021

During meiosis, protein ensembles in the nuclear envelope (NE) containing SUN- and KASH-domain proteins, called linker nucleocytoskeleton and cytoskeleton (LINC) complex, promote the chromosome motion. Yeast SUN-domain protein, Mps3, forms multiple meiosis-specific ensembles on NE, which show dynamic localisation for chromosome motion; however, the mechanism by which these Mps3 ensembles are formed during meiosis remains largely unknown. Here, we showed that the cyclin-dependent protein kinase (CDK) and Dbf4-dependent Cdc7 protein kinase (DDK) regulate meiosis-specific dynamics of Mps3 on NE, particularly by mediating the resolution of Mps3 clusters and telomere clustering. We also found that the luminal region of Mps3 juxtaposed to the inner nuclear membrane is required for meiosis-specific localisation of Mps3 on NE. Negative charges introduced by meiosis-specific phosphorylation in the luminal region of Mps3 alter its interaction with negatively charged lipids by electric repulsion in reconstituted liposomes. Phospho-mimetic substitution in the luminal region suppresses the localisation of Mps3 via the inactivation of CDK or DDK. Our study revealed multi-layered phosphorylation-dependent regulation of the localisation of Mps3 on NE for meiotic chromosome motion and NE remodelling.
Neural basis for regulation of vasopressin secretion by anticipated disturbances in osmolality
Authors: Kim Angela , Madara Joseph C , Wu Chen , Andermann Mark L , Lowell Bradford B
Published: September 2021

Water balance, tracked by extracellular osmolality, is regulated by feedback and feedforward mechanisms. Feedback regulation is reactive, occurring as deviations in osmolality are detected. Feedforward or presystemic regulation is proactive, occurring when disturbances in osmolality are anticipated. Vasopressin (AVP) is a key hormone regulating water balance and is released during hyperosmolality to limit renal water excretion. AVP neurons are under feedback and feedforward regulation. Not only do they respond to disturbances in blood osmolality, but they are also rapidly suppressed and stimulated, respectively, by drinking and eating, which will ultimately decrease and increase osmolality. Here, we demonstrate that AVP neuron activity is regulated by multiple anatomically and functionally distinct neural circuits. Notably, presystemic regulation during drinking and eating are mediated by non-overlapping circuits that involve the lamina terminalis and hypothalamic arcuate nucleus, respectively. These findings reveal neural mechanisms that support differential regulation of AVP release by diverse behavioral and physiological stimuli.
APOE4 is associated with elevated blood lipids and lower levels of innate immune biomarkers in a tropical Amerindian subsistence population
Authors: Garcia Angela R , Finch Caleb , Gatz Margaret , Kraft Thomas , Eid Rodriguez Daniel , Cummings Daniel , Charifson Mia , Buetow Kenneth , Beheim Bret A , Allayee Hooman , Thomas Gregory S , Stieglitz Jonathan , Gurven Michael D , Kaplan Hillard , Trumble Benjamin C
Published: September 2021

In post-industrial settings, apolipoprotein E4 (APOE4) is associated with increased cardiovascular and neurological disease risk. However, the majority of human evolutionary history occurred in environments with higher pathogenic diversity and low cardiovascular risk. We hypothesize that in high-pathogen and energy-limited contexts, the APOE4 allele confers benefits by reducing innate inflammation when uninfected, while maintaining higher lipid levels that buffer costs of immune activation during infection. Among Tsimane forager-farmers of Bolivia (N = 1266, 50% female), APOE4 is associated with 30% lower C-reactive protein, and higher total cholesterol and oxidized LDL. Blood lipids were either not associated, or negatively associated with inflammatory biomarkers, except for associations of oxidized LDL and inflammation which were limited to obese adults. Further, APOE4 carriers maintain higher levels of total and LDL cholesterol at low body mass indices (BMIs). These results suggest that the relationship between APOE4 and lipids may be beneficial for pathogen-driven immune responses and unlikely to increase cardiovascular risk in an active subsistence population.
Total parasite biomass but not peripheral parasitaemia is associated with endothelial and haematological perturbations in Plasmodium vivax patients
Authors: Silva-Filho João L , Dos-Santos João CK , Judice Carla , Beraldi Dario , Venugopal Kannan , Lima Diogenes , Nakaya Helder I , De Paula Erich V , Lopes Stefanie CP , Lacerda Marcus VG , Marti Matthias , Costa Fabio TM
Published: September 2021

Plasmodium vivaxis the major cause of human malaria in the Americas. HowP. vivaxinfection can lead to poor clinical outcomes, despite low peripheral parasitaemia, remains a matter of intense debate. Estimation of totalP. vivaxbiomass based on circulating markers indicates existence of a predominant parasite population outside of circulation. In this study, we investigate associations between both peripheral and total parasite biomass and host response in vivax malaria. We analysed parasite and host signatures in a cohort of uncomplicated vivax malaria patients from Manaus, Brazil, combining clinical and parasite parameters, multiplexed analysis of host responses, and ex vivo assays. Patterns of clinical features, parasite burden, and host signatures measured in plasma across the patient cohort were highly heterogenous. Further data deconvolution revealed two patient clusters, here termed Vivaxlowand Vivaxhigh. These patient subgroups were defined based on differences in total parasite biomass but not peripheral parasitaemia. Overall Vivaxlowpatients clustered with healthy donors and Vivaxhighpatients showed more profound alterations in haematological parameters, endothelial cell (EC) activation, and glycocalyx breakdown and levels of cytokines regulating different haematopoiesis pathways compared to Vivaxlow. Vivaxhighpatients presented more severe thrombocytopenia and lymphopenia, along with enrichment of neutrophils in the peripheral blood and increased neutrophil-to-lymphocyte ratio (NLCR). When patients’ signatures were combined, high association of total parasite biomass with a subset of markers of EC activation, thrombocytopenia, and lymphopenia severity was observed. Finally, machine learning models defined a combination of host parameters measured in the circulation that could predict the extent of parasite infection outside of circulation. Altogether, our data show that total parasite biomass is a better predictor of perturbations in host homeostasis inP. vivaxpatients than peripheral parasitaemia. This supports the emerging paradigm of aP. vivaxtissue reservoir, particularly in the haematopoietic niche of bone marrow and spleen.
Diagnosis of hearing deficiency using EEG based AEP signals: CWT and improved-VGG16 pipeline
Authors: Islam Md Nahidul , Sulaiman Norizam , Farid Fahmid Al , Uddin Jia , Alyami Salem A. , Rashid Mamunur , P.P. Abdul Majeed Anwar , Moni Mohammad Ali
Published: September 2021

Hearing deficiency is the world’s most common sensation of impairment and impedes human communication and learning. Early and precise hearing diagnosis using electroencephalogram (EEG) is referred to as the optimum strategy to deal with this issue. Among a wide range of EEG control signals, the most relevant modality for hearing loss diagnosis is auditory evoked potential (AEP) which is produced in the brain’s cortex area through an auditory stimulus. This study aims to develop a robust intelligent auditory sensation system utilizing a pre-train deep learning framework by analyzing and evaluating the functional reliability of the hearing based on the AEP response. First, the raw AEP data is transformed into time-frequency images through the wavelet transformation. Then, lower-level functionality is eliminated using a pre-trained network. Here, an improved-VGG16 architecture has been designed based on removing some convolutional layers and adding new layers in the fully connected block. Subsequently, the higher levels of the neural network architecture are fine-tuned using the labelled time-frequency images. Finally, the proposed method’s performance has been validated by a reputed publicly available AEP dataset, recorded from sixteen subjects when they have heard specific auditory stimuli in the left or right ear. The proposed method outperforms the state-of-art studies by improving the classification accuracy to 96.87% (from 57.375%), which indicates that the proposed improved-VGG16 architecture can significantly deal with AEP response in early hearing loss diagnosis.
The oldest species of Peltoperleidus (Louwoichthyiformes, Neopterygii) from the Middle Triassic (Anisian) of China, with phylogenetic and biogeographic implications
Authors: Xu Guang-Hui
Published: September 2021

The previously alleged ‘perleidid’ genus Peltoperleidus is a stem-neopterygian fish taxon with two or three horizontal rows of notably deepened flank scales. Until recently, members of this genus were known only from the Ladinian (late Middle Triassic) or near the Anisian/Ladinian boundary (~242 Ma) in southern Switzerland and northern Italy. Here, I report the discovery of a new species of the genus, Peltoperleidus asiaticus sp. nov., based on three well-preserved specimens from the Anisian (early Middle Triassic, ~244 Ma) of Luoping, eastern Yunnan, China. The discovery extends the geological range of Peltoperleidus by approximately two million years and documents the first record of the genus in Asia. Similar to its relatives (represented by P. macrodontus) from Europe, P. asiaticus sp. nov. is likely a small-sized durophagous predator with dentition combining grasping and crushing morphologies. Results of a cladistic analysis unite four species of Peltoperleidus as a monophyletic group within the Louwoichthyiformes, and suggest that the presence of two horizontal rows of notably deepened scales was independently evolved in Peltoperleidus and another stem-neopterygian taxon Altisolepis. P. asiaticus sp. nov. is nested at the base of Peltoperleidus, and a new family Peltoperleididae is proposed for the genus, contrasting the previous placement of Peltoperleidus in the poorly defined, paraphyletic ‘Perleididae’. Comparative studies of the basal peltoperleidid from China with its younger relatives from Europe provide new insights into the evolutionary origin and paleogeographic distribution of this clade.
An Evaluation of Post-Modern Theology of the Contemporary Period
Authors: ÜNLÜSOY Abdulhan
Published: September 2021

En genel anlamıyla teoloji, Tanrı hakkındaki konuşmalar olarak ifade edilir. Teolojinin konusu, Tanrı ve onunla ilgili olan her şeydir. Teoloji, bu anlamda, Tanrı-insan ilişkisi merkezli gelişen rasyonel bir gayrettir. Teoloji, Tanrı
inancının rasyonel temellendirilmesi anlamında yaşanılan çağın insanının algı dünyasıyla doğrudan ilgilidir. Teolojinin felsefeyle benzeşen tanımlayıcı özelliklerinden birisi, onun zorunlu olarak kendi olasılık koşullarını bünyesinde
barındırıyor oluşudur. Bu durum, onun, rasyonel zeminin dışında işleyen bir tutum olmasını gerektirmez. Elbette burada ima edilen şey, teolojinin sorularının metodik olarak aranması ve bu soruların cevaplarının kesin bir kavramsallık
içinde formüle edilmesidir. Bununla birlikte teolojinin, bilimsel metodolojinin en azından biçimsel işaretlerini sergilemesi, yani bilimsel bir nitelik taşıması gerekir. Dolayısıyla teoloji, hem savunusunu yaptığı dinin otantikliğini
korumalı hem de geçerli olduğu zaman dilimindeki kültür seviyesine uygun, o zaman diliminin insanına tatmin edici cevaplar sunma amacında olmalıdır. Her din, inananına, inanılması gereken esaslara niçin inanılması gerektiğini insanın
rasyonel, sosyokültürel seviyesine uygun bir şekilde açıklamak zorundadır. Yani teolojinin, içinde yaşanılan kültür, toplum ve bu ikisinin hitap ettiği bireylerin rasyonel seviyeleriyle yakından ilgisi vardır. Bu makale, bu görüşten
hareket ederek modern insanın bilinç durumunun hâkim olduğu modern dönemlerdeki teolojik algı ile modern sonrası çağdaş dönemlerin teolojik algısı arasındaki farkı ele almaya çalışır. Teolojik anlamda bu iki dönem arasında teolojik
eğilimler açısından farklılıklar vardır. Çünkü bu iki dönem arasında birey, kültür, toplum, dünyayı ve eşyayı algılayış farkı vardır. Modern dönemlerde akıl temelli işleyen rasyonel teolojik yaklaşımların hâkim olduğu dini alanı
aşındıran negatif bir tutum varken, modern sonrası dönemlerin teolojik anlayışı dine karşı daha olumsal, dini alanı nesneleştirici her tür akılsal ve politik totaliter tutumun karşısında yer alan bir eğilime sahiptir. Bu çalışma,
farklı eğilimlere sahip bu iki dönemin teolojik algılarının benzerlik ve farklılıklarını ortaya koymayı amaçlamaktadır.
al-Zamakhsharī’s Life in the Frame of her Poems and Psychological Analysis
Authors: ÇALIŞKAN Necmettin
Published: September 2021

Elliye yakın telifi ve Keşşâf isimli eseriyle müfessirler ve dilciler arasında adından çokça söz edilen âlimlerin başında Zemahşerî (ö. 538/1144) gelmektedir. Zemahşerî’nin telifleri ve hayatı hakkında çok sayıda araştırma yapılmıştır.
Ancak Zemahşerî’nin hayatıyla ilgili kaynaklarda detaylı ve doyurucu bilgiler yer almamaktadır. Zemahşerî’nin Keşşâfla birlikte elde ettiği şöhrete rağmen hayatı hakkında onun zihin yapısını anlamayı kolaylaştıracak detayların
olmaması hem tefsir hem de dil ilimleri sahasında bir eksiklik olarak görülebilir. Bu eksikliğin giderilmesine imkân tanıyacak kaynaklardın başında Zemahşerî’nin şiirleri gelmektedir. Zemahşerî erken yaşlardan itibaren şiir yazmaya
başlamış ve hayat hikayesini şiirleri arasında serpiştirmiştir. Ülkemizde Zemahşerî’nin hayatını şiirleri üzerinden ele alan bir çalışma bulunmamaktadır. Bu çalışmada Zemahşerî’nin hayatı; biyografik eserler yanında, şiirleri ve
telif ettiği eserler çerçevesinde incelenerek ele alınmıştır. Çalışmada Zemahşerî’nin okul çağlarında geçirdiği bir kaza sonucunda bacağından engelli kalmasının modern bilimin verileri çerçevesinde psikolojik tahlili, Mekke’ye
mücavir olmaya karar vermesinin sebepleri, mücâveretin ve “Arap diyarlarının her toprağına ayak bastım” dediği dönemin tarihinin netleştirilmesi, evliliği, devlet yöneticileriyle teması, Keşşâf’ın yazıldığı ve bitirildiği tarihlerin
tespiti ve daha birçok aydınlatılması gereken hususlar incelenmiştir. Yapılan çalışmada Zemahşerî’nin eğitim çağında bulunduğu sırada engelli kaldıktan sonra Hârizm’e bağlı Cürcâniye/Gürgenç şehrindeki medresede sıkı bir çalışma
dönemi geçirerek engelli olmanın dezavantajlarını avantaja çevirdiği tespit edilmiştir. Ayrıca Zemahşerî’nin Mekke’ye ilk mücavir olduğu yıl hakkında kaynaklarda birbiriyle çelişen farklı malumatlar yer almasına rağmen ilk ziyaretin
516 yılında 49 yaşındayken gerçekleştiği bulgusuna ulaşılmıştır.
Evaluation of Intubating Conditions during Direct Laryngoscopy using Sniffing Position and Simple Head Extension- A Randomised Clinical Trial
Authors: Singh Amanjot , Kaur Rupinder , Singh Gurpreet , Gupta Kewal Krishan
Published: September 2021

Introduction: Optimal laryngeal visualisation during direct laryngoscopy requires adequate positioning of the head and neck. Traditionally, Sniffing Position (SP) is the recommended position to provide superior glottic visualisation. However various studies in recent past have challenged the superiority of SP. Aim: To evaluate whether SP provides better glottic visualisation and ease of intubation {as assessed by total Intubation Difficulty Score (IDS) score as well as its individual components} compared to Simple Head Extension (SHE) during direct laryngoscopy and endotracheal intubation. Materials and Methods: The randomised clinical trial was conducted at GGS Medical College and Hospital, Faridkot, Punjab, India, from May 2019 to October 2020, on 220 patients. Patients undergoing elective surgeries under general anaesthesia were randomly divided into two groups. Laryngoscopy and tracheal intubation in Group I was done in SP, which was obtained by placing a non compressible pillow of height 8 cm under the patient’s head. Patients in Group II underwent laryngoscopy and tracheal intubation in SHE position. Glottic visualisation using modified Cormack and Lehane (CL) grades, IDS and sympathetic responses between the two groups were studied. The data was compared using student’s t-test and Chi-square test. Results: Cormack and Lehane Grade I was seen in 69 (62.7%) of patients in Group I as against 51(46.4%) of patients in Group II (p-value=0.015). Easy intubation (total IDS score=0) was seen in a greater number of patients in Group I (60.9%) as compared to Group II (40.95%) (p-value=0.003). Slight difficulty in intubation (total IDS score=1-5) was encountered in 50.0% of patients in group II (n=55) and 35.5% of patients in group I (n=39) (p-value=0.029). Conclusion: The present study concluded that use of SP resulted in better glottic visualisation and was associated with favourable intubation conditions as compared to SHE position.
Parasitoses intestinais e fatores de risco associados em crianças em um município do Nordeste Brasileiro
Authors: Nunes Chaves Jairina Nunes , Araújo Cunha Gizelia , Silva Chaves Tharliane , Araújo Corrêa Anderson , Carvalho Santana Ewaldo Eder , Seabra Nogueira Rita de Maria
Published: September 2021

Introdução: os parasitas gastrintestinais são causas de morbidade em crianças, podendo determinar quadros de anemia e diarréria. Poder estar associados as condições socioeconômicas, saneamento básico e práticas de higiene. Objetivo: O objetivo desta pesquisa foi identificar as parasitoses intestinais e os fatores de riscos associados em crianças menores de 12 anos cadastradas em duas Unidades Básicas de Saúde do município de Caxias, estado do Maranhão. Metodologia: Neste estudo observacional e transversal 422 exames coproparasitológicos pela técnica de Hoffman, Pons e Janner foram realizados. Para comparar as proporções utilizou-se o teste Qui-quadrado (X2) ou teste exato de Fisher. Empregou-se análises univariadas e multivariadas por regressão logística para avaliar a associação entre a infecção por enteroparasitas e os fatores de riscos. Resultados: A frequência de parasitas intestinais foi 49,05%, sendo predominante o Ascaris lumbricoides (68,18%) e a Entamoeba sp. (65,38%). Conforme a análise estatística, ingerir água sem tratamento domiciliar e não lavar as mãos antes das refeições podem ser considerados como fatores de risco para as enteropatias parasitárias. Conclusão: Ressalta-se a necessidade de implementar políticas públicas que visem reduzir as altas taxas destes parasitas, e que contribuam para melhorar a qualidade de vida dessa população.
Inalação da fumaça do tabacco provoca alterações histopatológicas no nervo olfatório de ratos
Authors: Pereira de Almeida Ferreira Flávio José , Rosa Rodrigo César , Espíndula Ana Paula , Gonçalves Pereira Vandair , De Lima Pereira Sanívia Aparecida , Gomide Cardoso Fabrizio Antonio
Published: September 2021

Introdução:o tabagismo é uma das principais causas evitáveis de mortes no mundo representando um problema de saúde pública mundial. Objetivo:investigar a relação da exposição passiva à fumaça principal do cigarro e as possíveis alterações histomorfométricas das células gliais, arteríolas e da matriz extracelular do nervo olfatório de ratas. Metodologia:estudo experimental, analítico e quantitativo, vinte animais wistar fêmeas randomizados em dois grupos controle e tabaco, foram expostos a inalação da fumaça principal do cigarro por 60 dias utilizando dispositivo validado na literatura. Resultados:a exposição a inalação da fumaça principal do cigarro resultou em alterações significativas no grupo tabaco, tais como, elevação nos níveis de cotinina no plasma sanguíneo, aumento na espessura da parede dos vasos sanguíneos, aumento na porcentagem do colágeno total do tecido, diminuição no número total de astrócitos e aumento no número total de micróglias. Conclusão:a exposição a fumaça principal do cigarro resulta em alterações histomorfométricas que poderiam causar alterações funcionais no nervo olfatório como perda sensorial olfativa. Nossos achados são fortes o suficiente para servir como alerta a toda população e às autoridades de saúde, no que se refere as leis antifumo, principalmente em ambientes fechados.
Estudo das prevalências de distúrbios metabólicos em pacientes obesos e em portadores de hepatite C
Authors: De jesus Correia Caroline , Muniz Carvalho Fernandes da Cunha Simone , Rugieri Pacheco Sidelcina , Araújo Leila Maria Batista , Nunes Vinicius Santos , Schinoni Maria Isabel
Published: September 2021

Introdução: A infecção crônica pelo vírus da hepatite C (HCV) e a obesidade podem induzir esteatose hepática e diabetes mellitus (DM). Objetivo: Avaliar a prevalência de obesidade e de distúrbios metabólicos em pacientes com HCV; estudar a prevalência de HCV e os distúrbios metabólicos em pacientes obesos. Comparar o perfil glicêmico entre os grupos. Metodologia: estudo analítico, com pacientes acompanhados nos ambulatórios de Hepatite C e Obesidade. Variáveis analisadas: glicemia, hemoglobina glicada (A1C), esteatose hepática, HCV, estágio de fibrose hepática e dados sociodemográficos. Resultados: no ambulatório de obesidade 45 pacientes foram avaliados, dos quais 6,7% tinham hepatite C, 40% DM e 61-73% esteatose hepática. As médias das enzimas hepáticas (U/L) foram: AST 22,9; ALT 25,2; FAL 146,5 e GGT 63. Nos obesos com DM, 72,2% apresentavam A1C < 7%. A segunda amostra continha 159 portadores de HCV do ambulatório de hepatologia: 17,9% tinham obesidade, 18,9% DM e 27% esteatose hepática. As médias das enzimas hepáticas (U/L) consistiram em: AST 70,5; ALT 90,6; FAL 108,5 e GGT 131,7. Entre os diabéticos com HCV, 52% não apresentavam A1C < 7%. Conclusão: foi encontrada alta prevalência de hepatite C em pacientes com obesidade (6,7%) quando comparados com a população de Salvador (1,5-1,8%). Os distúrbios metabólicos foram mais frequentes entre obesos, porém os diabéticos com obesidade revelaram A1C menores do que os diabéticos com HCV, sugerindo, neste estudo, que pode existir interferência viral no controle glicídico. A esteatose hepática foi mais prevalente entre obesos.
Avaliação da rugosidade e perda de massa de resinas compostas laboratoriais após a escovação com dentifrício clareador
Authors: Alves Gomes Jéssica , Maia Barreto de Oliveira Viviane
Published: September 2021

Introdução: Os dentifrícios clareadores têm sido desenvolvidos para oferecer um melhoramento estético, porém por apresentarem maior abrasividade, podem desenvolver efeitos adversos na superfície de materiais restauradores, como aumento da rugosidade superficial, comprometendo a sobrevida das restaurações. Objetivo: Analisar a rugosidade e comportamento da massa de duas resinas compostas laboratoriais submetidas à escovação com água destilada (controle) e com dentifrício abrasivo (DA), Colgate Luminous White®. Metodologia: Foram confeccionadas 40 amostras, 20 a partir da Resina fotopolimerizável Opallis Lab® e 20 de blocos para sistema CAD/CAM (Brava Block®), divididos em quatro grupos: Opallis Lab® + água destilada, Opallis Lab® + DA, Brava Block® + água destilada, Brava Block® + DA. As amostras foram pesadas e a rugosidade aferida antes e após a escovação. Foi utilizada uma máquina de escovação em 14.690 ciclos para simulação de 1 ano de escovação. Os dados foram tabulados e analisados quanto à variância (ANOVA) e posteriormente realizados o teste de Tukey, comparando as médias, duas a duas.  Resultados: Quanto ao DA, a resina fotopolimerizável apresentou comportamento limítrofe comparado ao grupo controle, já o bloco CAD/CAM foi estatisticamente significante. Em ambos, a rugosidade reduziu no grupo controle enquanto que no grupo teste aumentou. A perda de massa apenas foi estatisticamente significante na resina fotopolimerizável. Quando comparados os tipos de resina, não houve significância estatística quanto à rugosidade e a perda de massa. Conclusão: As resinas apresentam comportamentos semelhantes, mas os dentifrícios abrasivos não são recomendados para escovação de materiais restauradores, pois interferem negativamente na rugosidade.
Respiratory muscle strength and exercise capacity of children and adolescents with chronic liver diseases Exercise capacity in liver disease
Authors: Magalhães Novais Michelli Christina , Gomes Neto Mansueto , Da Silva Oliveira Yuri , De Souza Pereira Tatiane , Souza Moreira de Almeida Suzana , Rodrigues Silva Luciana
Published: September 2021

Introdution: Chronic liver diseases are characterized by inflammatory and fibrotic lesions of the liver that cause systemic complications. These complications can negatively interfere with the respiratory muscle strength and exercise capacity of developing children and adolescents. Objectives: To compare respiratory muscle strength and exercise capacity in children and adolescents with chronic hepatopathy, using reference values from healthy individuals of the same age. Methods: A cross-sectional study was performed. Children and adolescents from 6 to 16 years old with chronic hepatopathies were included. For the evaluation of respiratory muscle strength, the maximal respiratory pressures were measured through manovacuometry. A six-minute walk test was used to assess exercise capacity. The Wilcoxon test was used to verify the difference between the evaluated and predicted values of the distance traveled. Results: In total, 40 subjects were analyzed; 57.5% of the subjects were female, and the subjects had a mean age of 11.68±2.82 years. In the comparison between the measured and predicted maximal respiratory pressures, a difference of -17.71 cmH2O (p< 0.001) was found for the maximal inspiratory pressure, and a difference of -30.68 cmH2O (p< 0.001) was found for the maximal expiratory pressure. Regarding exercise capacity, the measured average distance traveled was 346.46±49.21 m, which was 185.54m (p< 0.001) less than the predicted value. Conclusions: Children and adolescents with chronic liver disease have reduced respiratory muscle function and exercise capacity.
Prevalência de doença hepática gordurosa não alcoólica apontada por ultrassonografia em pacientes com diabetes tipo 2 hospitalizados
Authors: Batista de Oliveira Lucian , Dos Santos Torres Maria Roseneide
Published: September 2021

Introdução: A doença hepática gordurosa não alcoólica (DHGNA) é caracterizada pela infiltração gordurosa do fígado, em indivíduos sem histórico de ingestão significativa de álcool ou de outras doenças hepáticas. A DHGNA é subdividida em fígado gorduroso não alcoólico e esteato-hepatite não alcoólica (NASH). A resistência à insulina e o diabetes mellitus tipo 2 (DM2) apresentam importante associação com DHGNA. Objetivos: Avaliar a prevalência de DHGNA, predita por ultrassonografia, em pacientes com DM2 hospitalizados, verificando sua associação com tempo de DM2, comorbidades, terapêutica previamente utilizada, parâmetros antropométricos e controles glicêmico e pressórico. Metodologia: Estudo observacional, transversal e analítico, realizado nas enfermarias de Clínica Médica e de Endocrinologia do Hospital Universitário Alcides Carneiro, envolvendo pacientes adultos com DM2. Foram excluídos pacientes com outras hepatopatias diagnosticadas, com histórico de etilismo significativo ou que não quiseram participar da pesquisa. Resultados: A amostra válida foi de 20 pacientes, com média de idade de 62,9 anos (± 10,9). A prevalência de DHGNA foi de 40%. Houve associação estatisticamente significativa entre DHGNA e maiores níveis de índice de massa corpórea (IMC) (p = 0,025) e de circunferência abdominal (CA) (p = 0,041). Entre as comorbidades, houve relação entre DHGNA e hipotireoidismo (p = 0,049). Conclusão: Apesar das limitações relacionadas ao tamanho da amostra, observa-se que a DHGNA está associada à obesidade central, o que é apontado pelos maiores níveis de IMC e de CA, de forma que uma abordagem multidisciplinar pode impedir o desenvolvimento ou a progressão de DHGNA.
Cytogenetic and molecular characterization of an SRY-negative 46, XX ovotesticular DSD
Authors: Moura Carvalho Natalia Dayane , Carvalho Passos Tirciana , Mesquita Gadelha Prazeres Vania , Fantin Cleiton
Published: September 2021

Introduction: Ovotesticular disorder of sex development is a rare condition by the concomitant presence of testicular and ovarian tissue, and usually presents genital ambiguity. Are chromosomally heterogeneous, and cytogenetic analyses is relevant. Objective: report on a patient from Manaus, Amazonas state with ovotesticular disorder of sex differentiation 46, XX and SRY-negative. Case report: Patient of 19 years, first child of non-consanguineous parents. At birth, the patient was diagnosed with genital ambiguity and, without early diagnosis, he was registered as being of the male sex. The patient underwent surgery to correct bilateral cryptorchidism, orchiopexy and colpectomy. During puberty, he developed female and male sexual characteristics. Endocrinological (normal total testosterone and estradiol as high follicle-stimulating hormone and luteinizing hormone), histopathological (right gonad, ovarian follicles and left gonads, atrophic testicles), karyotype (46, XX) and molecular (SRY-negative). Diagnosis of ovotesticular disorder of sex development was established. The patient chose to remain male and underwent bilateral mastectomy, vaginal colpectomy and bilateral gonadectomy. Currently, the patient receives hormonal replacement therapy, follow-up with a multi-professional approach and awaits masculinizing genitoplasty. Discussion: In diagnostic research, cytogenetic and molecular analysis are primary tools. For OT-DSD individuals with 46, XX, the female sex is suggested as the best sex option. Unlike the reported cases, the patient chose the male sex, since the sex at registration of birth was important in his choice. Conclusion: Cytogenetic and molecular analyses allowed us to assist in the etiological diagnosis of the patient with OT-DSD from Manaus. However, molecular analyses are necessary to elucidate the genes involved in the sexual determination of this patient.
Transdramaturgias nas Artes do Corpo no Japão
Authors: Greiner Christine , Aoki Beatriz Yumi
Published: September 2021

A última década tem sido marcada por discussões que repensam a noção de dramaturgia a partir do surgimento de novas tecnologias e debates políticos. No Japão, este termo nunca foi amplamente usado, a não ser para obras concebidas por artistas Ocidentais. Entretanto, isto não significa que não exista uma dramaturgia nas experiências artísticas japonesas. Trata-se de uma epistemologia distinta para lidar com as relações entre texto e ação e, por isso, pede por outras abordagens. A proposta deste artigo é testar o termo transdramaturgia, tendo em vista buscar uma aproximação com alguns dispositivos lógico-afetivos identificados em experiências de artistas japoneses. Não se trata de impor uma nova classificação, mas sim, de chamar a atenção para uma lógica trans (não dicotômica), que evidencia como o processo dramatúrgico tem início antes da organização da cena artística (narrativas e gestos), durante a gênese de um pensar/sentir corpos e ambientes. Partimos de performances transgênero que desafiam a dicotomia masculino/feminino desde o Japão medieval; e de experimentos transdimensionais recentes, que negligenciam dicotomias entre real e ficcional, pessoa e objeto, radicalizando a noção de criação como insurgência de novos sentidos para a arte. Busca-se, assim, ampliar os debates sobre dramaturgia contemporânea.
Pra frente o pior: corpo e dramaturgia em negociação
Authors: Cardoso Thereza Christina Rocha , Campos Andrei Bessa Siqueira
Published: September 2021

Estudo da dramaturgia do corpo no espetáculo Pra Frente o Pior (2016), Inquieta Cia. (Fortaleza/CE), nomeada durante seu processo de criação como dramaturgia da negociação. O texto observa o interesse do grupo pelo programa performativo enquanto acompanha o seu traslado do campo da performance ao da cena-não-cena (FABIÃO, 2013). Assim, desenvolve uma análise da ação (drama) em situação não-dramática para dela extrair seu caráter intransitivo. Através da assim chamada negociação, investiga os modos pelos quais um coletivo de/em criação pode devir comunidade, conceito que apreende das obras de George Bataille (1943), Jean-Luc Nancy (2016) e Maurice Blanchot (2013). Pra Frente o Pior estabelece tramas insuspeitas com a obra homônima de Samuel Beckett (1983) permitindo a este artigo refletir sobre o nosso devir-comunidade, os moveres coletivos hoje, questão premente de ser enfrentada na biopolítica neoliberal vigente. Nesta suposta dramaturgia social do fim, “seguir adiante” é a questão que nos move.
Dramaturgia da experiência: corpo, autobiografia e feminismos na criação de No te pongas flamenca!
Authors: Fagundes Patricia , Kersting Juliana
Published: September 2021

O artigo reflete sobre o processo de criação cênica e dramatúrgica de [título do espetáculo removido para avaliação], espetáculo desenvolvido entre 2017 e 2019 como parte de pesquisa de Mestrado da atriz e bailarina [nome do autor removido para avaliação]. Na montagem, repertorio corporal, autobiografia e feminismos operam como fontes e provocações de uma narrativa que busca compor outras histórias, nossas histórias, distintas dos discursos do poder. Em intersecções entre teoria e prática artística, corpo e conceito, propõe-se uma dramaturgia da experiência feita de subjetividade, memória, desejo, processo, encontros e desencontros. Ao mesmo tempo que é feito de experiência, o próprio fazer cênico/dramatúrgico é experiência, ou seja, o que fazemos nos faz e tece narrativas no mundo.
Ecologies of Dramaturgy in Dance Creation: A Conversation
Authors: Baird Haley , Montesi Vanessa , Dugan Dana , Nye Matthew-Robin , Willkie Angélique , Scott Christian , Scialom Melina
Published: September 2021

AW é Jamaicana, Preta, dançarina mulher cisgênero e dramaturga. Dois interesses paralelos emergiram gradualmente ao longo de sua carreira – a contribuição do performer ao processo criativo, e a dinâmica da operação necessariamente colaborativa que é a coreografia contemporânea. Esta entrevista com a artista-pesquisadora reporta sua experiência artística e o processo criativo da obra Confession Publique, ao qual ela ocupa a posição triádica de dramaturga, dançarina e pesquisadora auto-etnógrafa, compondo uma conversa dialógica entre artistas interdisciplinares e pesquisadores do projeto Dramaturgical Ecologies (sediado na Anonimo). Para além de uma entrevista, este projeto polivocal–centrado nos temas de agenciamento, dramaturgia, corporalização e movimento–migrou do físico para o virtual, respondendo a reconfiguração biopolítica causada pela pandemia do COVID-19. Esta transição ativou  tensões e ressonâncias no diálogo que se tornaram limitações facilitadoras, onde os corpos envolvidos na pesquisa se tornaram parte da co-composição dramatúrgica do processo de escrita deste texto. O resultado está distribuído nas páginas que seguem, tomando forma de uma escrita performativa dialógica-reflexiva, criada a partir de um processo de pensamento coletivo.