bluuebunny/crossref_metadata_2025 huggingface dataset:
From expression pattern to genetic association in asthma and asthma-related phenotypes
Authors: Vaillancourt Vanessa T , Bordeleau Martine , Laviolette Michel , Laprise Catherine
Published: November 2012

Background

Asthma is a complex disease characterized by hyperresponsiveness, obstruction and inflammation of the airways. To date, several studies using different approaches as candidate genes approach, genome wide association studies, linkage analysis and genomic expression leaded to the identification of over 300 genes involved in asthma pathophysiology. Combining results from two studies of genomic expression, this study aims to perform an association analysis between genes differently expressed in bronchial biopsies of asthmatics compared to controls and asthma-related phenotypes using the same French-Canadian Caucasian population.

Results

Before correction, 31 of the 85 genes selected were associated with at least one asthma-related phenotype. We found four genes that survived the correction for multiple testing. The rs11630178 in aggrecan gene (AGC1) is associated with atopy (p=0.0003) and atopic asthma (p=0.0001), the rs1247653 in the interferon alpha-inducible protein 6 (IFI6), the rs1119529 in adrenergic, alpha-2A-, receptor (ADRA2A) and the rs13103321 in the alcohol dehydrogenase 1B (class I), beta polypeptide (ADH1B), are associated with asthma (p=0.019; 0.01 and 0.002 respectively).

Conclusion

To our knowledge, this is the first time those genes are associated with asthma and related traits. Consequently, our study confirms that genetic and expression studies are complementary to identify new candidate genes and to investigate their role to improve the comprehension of the complexity of asthma pathophysiology.
The immunoreceptor tyrosine-based activation motif (ITAM) -related factors are increased in synovial tissue and vasculature of rheumatoid arthritic joints
Authors: Crotti Tania N , Dharmapatni Anak ASSK , Alias Ekram , Zannettino Andrew CW , Smith Malcolm D , Haynes David R
Published: November 2012

Introduction

The immunoreceptor tyrosine-based activation motif (ITAM) pathway provides osteoclast co-stimulatory signals and regulates proliferation, survival and differentiation of effector immune cells. In the osteoclast, the receptors Triggering Receptor Expressed on Myeloid cells 2 (TREM2) and Osteoclast Associated Receptor (OSCAR) and their respective adaptor proteins, DAP12 and FcRγ mediate ITAM signals and induce calcium signaling and the crucial transcription factor, NFATc1. In rheumatoid arthritis (RA), OSCAR expression by monocytes is inversely correlated with disease activity. Additionally, serum levels of OSCAR are reduced in RA patients versus healthy controls suggesting that expression and secretion or cleavage of soluble (s) OSCAR is immune modulated. Recent data suggest that endothelial cells may also be a source of OSCAR.

Methods

ITAM receptors, their adaptor proteins, and NFATc1 and cathepsin K were detected in human synovial tissues by immunohistochemistry. Synovial tissues from patients with active RA were compared with tissue from patients in remission, osteoarthritis (OA) patients and healthy individuals. OSCAR was measured by immunoassay in synovial fluids recovered from active RA and OA patients. Endothelial cells were cultured with or without 5 ng/mL TNF-α or IL-1β over 72 hours. Temporal expression of OSCAR mRNA was assessed by qRT PCR and OSCAR protein in the supernatant was measured by ELISA.

Results

Significantly higher (P < 0.05) NFATc1-positive inflammatory cell aggregates were found in active RA tissues than in healthy synovial tissue. Similarly, the percentage of OSCAR, FcRγ, DAP12 and TREM2 positive cells was significantly higher in active RA tissues compared to the healthy synovial tissue. Notably, OSCAR was strongly expressed in the microvasculature of the active RA tissues (9/9), inactive RA (8/9) weakly in OA (4/9) but only in the lumen of healthy synovial tissue (0/8). OSCAR levels were detected in synovial fluids from both RA (47 to 152 ng/mL) and OA (112 to 145 ng/mL) patients. Moreover, OSCAR mRNA expression and soluble OSCAR release was stimulated by TNF-α and IL1-β in cultured endothelial cells.

Conclusions

Increased levels of ITAM related factors were present in synovial tissue from active RA joints compared to OA and healthy joints. OSCAR was strongly expressed by the vasculature of active RA patients and membrane bound and soluble OSCAR was stimulated by inflammatory mediators in endothelial cells in vitro.
IL-32 and IL-17 interact and have the potential to aggravate osteoclastogenesis in rheumatoid arthritis
Authors: Moon Young-Mee , Yoon Bo-Young , Her Yang-Mi , Oh Hye-Joa , Lee Jae-Seon , Kim Kyoung-Woon , Lee Seon-Yeong , Woo Yun-Ju , Park Kyung-Su , Park Sung-Hwan , Kim Ho-Youn , Cho Mi-La
Published: November 2012

Introduction

Interleukin (IL)-32 and IL-17 play critical roles in pro-inflammatory responses and are highly expressed in the synovium of patients with rheumatoid arthritis (RA). We investigated the relations between these two cytokines (IL-17 and IL-32) for their ability to induce each other and to stimulate osteoclasts in RA fibroblast-like synoviocytes (FLSs) and T cells.

Methods

FLSs were isolated through surgical synovectomy obtained from patients with RA or osteoarthritis (OA). Real-time PCR were performed to evaluate the expression of IL-32, IL-17 and osteoclast-related genes. Immunohistochemical staining and tartrate-resistant acid phosphatase (TRAP) staining were performed to determine the distribution of inflammatory cytokines and the presence of osteoclastogenesis.

Results

IL-17 induced the expression of IL-32 in the FLSs from RA patients, as assessed by microarray. IL-32 production was increased by IL-17. IL-32 in the FLSs from RA patients induced the production of IL-17 in CD4+ T cells. IL-32 and IL-17 were colocalized near TRAP-positive areas in joint specimens. IL-17 and IL-32 synergistically induced the differentiation of osteoclasts, as demonstrated by the expression of osteoclast-related genes. IL-32 and IL-17 also could induce resorption by osteoclasts in a RANKL-dependent manner.

Conclusions

IL-17 affected the expression of IL-32 in FLSs of RA patients and IL-32 induced the production of IL-17 in CD4+ T cells. Both IL-17 and IL-32 cytokines can reciprocally influence each other's production and amplify the function of osteoclastogenesis in the in RA synovium. Separately, IL-17 and IL-32 each stimulated osteoclastogenesis without RANKL. Together, the two cytokines synergistically amplified the differentiation of osteoclasts, independent of RANKL stimulation.
Monophasic versus biphasic defibrillation for pediatric out-of-hospital cardiac arrest patients: a nationwide population-based study in Japan
Authors: Tanabe Seizan , Yasunaga Hideo , Koike Soichi , Akahane Manabu , Ogawa Toshio , Horiguchi Hiromasa , Hatanaka Tetsuo , Yokota Hiroyuki , Imamura Tomoaki
Published: November 2012

Introduction

Conventional monophasic defibrillators for out-of-hospital cardiac-arrest patients have been replaced with biphasic defibrillators. However, the advantage of biphasic over monophasic defibrillation for pediatric out-of-hospital cardiac-arrest patients remains unknown. This study aimed to compare the survival outcomes of pediatric out-of-hospital cardiac-arrest patients who underwent monophasic defibrillation with those who underwent biphasic defibrillation.

Methods

This prospective, nationwide, population-based observational study included pediatric out-of-hospital cardiac-arrest patients from January 1, 2005, to December 31, 2009. The primary outcome measure was survival at 1 month with minimal neurologic impairment. The secondary outcome measures were survival at 1 month and the return of spontaneous circulation before hospital arrival. Multivariable logistic regression analysis was performed to identify the independent association between defibrillator type (monophasic or biphasic) and outcomes.

Results

Among 5,628 pediatric out-of-hospital cardiac-arrest patients (1 through 17 years old), 430 who received defibrillation shock with monophasic or biphasic defibrillator were analyzed. The number of patients who received defibrillation shock with monophasic defibrillator was 127 (30%), and 303 (70%) received defibrillation shock with biphasic defibrillator. The survival rates at 1 month with minimal neurologic impairment were 17.5% and 24.4%, the survival rates at 1 month were 32.3% and 35.6%, and the rates of return of spontaneous circulation before hospital arrival were 24.4% and 27.4% in the monophasic and biphasic defibrillator groups, respectively. Hierarchic logistic regression analyses by using generalized estimation equations found no significant difference between the two groups in terms of 1-month survival with minimal neurologic impairment (odds ratio (OR), 1.57; 95% confidence interval (CI), 0.87 to 2.83; P = 0.14) and 1-month survival (OR, 1.38; 95% CI, 0.87 to 2.18; P = 0.17).

Conclusions

The present nationwide population-based observational study could not confirm an advantage of biphasic over monophasic defibrillators for pediatric OHCA patients.
This Issue of Geophysics
Authors: Nemeth Tamas
Published: November 2012

In this article, the Editor of Geophysics provides an overview of all technical articles in this issue of the journal.
Thanks to our donors and volunteers for a successful 2009
Authors: Servos Gary
Published: November 2012

This past year has been both challenging and successful for the SEG Foundation. I want to thank all our 2009 donors, our volunteers, and our Tulsa staff for their generosity, their wisdom, and their hard work.
The global energy and environment challenge
Authors: Lumley David
Published: November 2012

Whether you are a veteran member of SEG or a new recruit about to start your career, I can't think of a more important and exciting time to be a geophysicist. We are currently facing an unsustainable future where society's demands for energy are competing with the basic need to protect the environment. As of today, it is uncertain where we will find the future energy supply required to meet global demand, and we are equally uncertain about the full impact our energy use is having on global climate change and the precious environment that we depend upon for life. Talk about a high-stakes situation! It's no wonder governments can't agree on greenhouse gas (GHG) emissions and trillions of dollars in GHG taxes and redistribution payments, and people are taking to the streets in protest (as in the recent climate summit in Copenhagen, for example).
Making an Impact: The SEG/Chevron Student Leadership Symposium
Authors: Chinsethagid Candice
Published: November 2012

The third SEG/Chevron Student Leadership Symposium (SLS) was held in Houston, USA, 24–25 October 2009 for 50 Student Chapter officers from around the world. Universities from 26 countries were represented with 80% of the students residing outside the US. All participants were awarded a travel grant providing airfare, accommodation, and meal expenses for the SLS and the duration of the SEG Annual Meeting. Students were chosen from an applicant pool of 76. SLS is certainly fulfilling its promise as a high-energy, high-demand, and high-value SEG student program.
Seam update: Models for EM and gravity simulations
Authors: Stefani Joe , Frenkel Michael , Bundalo Neda , Day Richard , Fehler Michael
Published: November 2012

The primary objective of SEAM is to conduct geophysical modeling of relevance to the petroleum industry. Most of the discussion to date regarding the project and its Earth model has focused on its seismic aspects. Since the initial modeling objective of the SEAM Phase I project was variable-density acoustic simulation, P-wave velocity and density were the primary parameters defined for the model. However, the project is also simulating gravity, controlled-source electromagnetic (CSEM), and magnetotelluric (MT) data acquisition, which require the construction of a resistivity volume as well. These nonseismic simulations are funded under a research subcontract (#07121–2001) from the Research Partnership to Secure Energy for America (RPSEA).
Reviews
Authors: Treitel Sven , Bartel David
Published: November 2012

Nonlinear Least Squares for Inverse Problems, Guy Chavent. ISBN 978-90-481-2785-6, Springer, 2009, 360 pp., €119.95 (hardback). Applications of Seismic Anisotropy in the Oil and Gas Industry (OTEIII), V. Grechka, ISBN 978-90-73781-68-9, EAGE Publications, 2009, 171 pp., €77 (non-members), €55 (EAGE members).
Memorials
Authors:   EAGO, Shoham Yoram , Yowell David , Danbom Steve , Davogustto Oswaldo , Dodson Jan , Hoover Gary , Marfurt Kurt
Published: November 2012

Memorials for: Nicolay Savostyanov 1929–2009 Roger Adams Young 1943–2009
What does it mean to be an international society?
Authors: Bradford John
Published: November 2012

Finding practical solutions to global-scale problems is ultimately enhanced by, and indeed requires the collaboration and cooperation of the global scientific community. Three commonly recognized problems that fall into this category, and with ever-increasing urgency, are the threatened supply of fresh water, global climate change, and meeting the energy demands of modern society. The SEG membership is actively engaged in all of these issues, and the science and technology needed to address these problems, of course, knows no national boundaries. International scientific societies play a role in the solution to these problems by providing forums for improved communication that ultimately lead to opportunities for collaboration among geographically diverse scientific communities. The organizations may also enhance the research enterprise by helping coordinate scientific activities or maintaining and providing access to data sets. These relatively simple concepts may not be easily implemented because organizations must balance all activities with best business practices and responsible stewardship of funds while seeking to work in the best interest of their members.
Geophysics field education: Better learning by doing
Authors: Stewart Robert R. , Khan Shuhab , Hall Stuart , Liner Christopher , Wong Joe
Published: November 2012

A fascination with natural phenomena, a love of the outdoors, and an interest in using advanced technologies draw many to geophysics. In addition, the soul of an exploration geophysicist will likely harbor an energetic curiosity along with the spirit to search for something valuable. Inherent in this quest and the practice of geophysics is a field survey—with its adventure, camaraderie, and measurements. The survey is usually about imaging the subsurface to discover or define something buried. Geophysicists are thus called to make a contribution toward scientific understanding of the Earth and, via conscientious resource recovery, an improvement in prosperity. Central to this endeavor is making observations and acquiring data.
Memorials
Authors: Treitel Sven
Published: November 2012

Memorials for: M. Turhan (Tury) Taner 1927–2010
SEG Advanced Modeling Project: Completion of Phase I acoustic simulations
Authors: Fehler Michael
Published: November 2012

The SEG Advanced Modeling Project reached a milestone with completion of the simulations of 62,478 shots on the SEAM Phase I variable-density acoustic model. A further 2403 shots were simulated on the model where the free upper surface was replaced by an absorbing upper surface. For the free-surface data set, shots were located on a 150-m grid spread across the surface of the model. Traces were gathered along a square grid centered at each source. The trace spacing was 30 m across a square grid with a side of 19.8 km but extending only to the edge of the model so a maximum of 436,921 traces was collected for each shot. Quality control evaluation of all data has been completed and the traces are stored in 10:1 compressed shot gathers.
Reviews
Authors: Green William R. , Jin Doo Jung
Published: November 2012

Challenged by Carbon: The Oil Industry and Climate Change, by Bryan Lovell, ISBN 978-0-521-14559-6, Cambridge, 2010, 212 pp., US $29.99. The Cambridge Handbook of Earth Science Data, by Paul Henderson and Gideon M. Henderson. ISBN 978-0-521-69317-2 (paperback), Cambridge, 2009, 277 pp., US $30.00.
Signals
Authors: Alfonso Hector A. , Russell Brian , Hertzberg Martin , Parker Calvin A. , Pennington Wayne D. , Turpening Roger M. ,   (on behalf of all “SEG Yoopers”)
Published: November 2012

Signals are letters to the editor submitted by readers of The Leading Edge.
Memorials
Authors: Witherly Ken , Juhas Allan , O'Toole Barney , Podolsky Jean , Podolsky George , Yowell David
Published: November 2012

Memorials for: George Podolsky 1932–2010 Ed Stewart 1931–2010
Reviews
Authors: Moon Wooil M. , Taylor Patrick , Haines Seth S. , Green William R.
Published: November 2012

Megaflooding on Earth and Mars, by Devon M. Burr, Paul A. Carling, and Victor R. Baker (eds.), ISBN 978-0-521-86851-5, Cambridge University Press, 2009, pp 319, US $140 (hardback) American and Tethyan Fold-Thrust Belts, by Dietrich Roeder, ISBN 978-3-443-11032-1, E. Schweizerbart, 2009, 168 pp., € $84.00 US $111.31 (hardback) Ancient Landscapes of the Colorado Plateau, by Ron Blakey and Wayne Ranney, ISBN 978-1934656037, Grand Canyon Association, 156 pp., US $23.07 (paperback) Beyond Smoke and Mirrors: Climate Change and Energy in the 21st Century, by Burton Richter, ISBN 978-0-521-74781-3, Cambridge University Press, 2010, 226 pp. US $29.99
Underground imaging
Authors: Kendrick Alexander
Published: November 2012

An increasingly difficult problem is the challenge to provide potable water for the world's expanding population. Electromagnetic methods originally used to locate oil can be used to locate shallow aquifers. Typically, electromagnetic studies track salinity of aquifers, but similar technology could be applied to detect shallow new aquifers. The potential for detecting aquifers also applies to mapping underground river systems as well as providing more insight to understanding the local hydrology in certain areas. Controlled-source electromagnetic studies of shallow aquifers are relatively untested compared to studies to detect oil reservoirs with time-domain electromagnetics.
Increasing SEG's presence in Europe
Authors: Koster Klaas
Published: November 2012

As is to be expected from someone who lives and works in Europe, I would like SEG to have a more significant presence in this part of the world. It turns out that I'm not the only one with that desire; many of you who also reside in Europe have been open and straightforward in communicating your desire to continue to grow as geophysicists using the products that SEG delivers. With that in mind, we as a Society have undertaken an in-depth look at what is provided to our European members and have concluded that the SEG is underserving this vital, vibrant constituency.
Reflections on a tour
Authors: Méndez-Hernández Efrain
Published: November 2012

I wish to thank SEG for the opportunity to share knowledge, meet people, and visit interesting places as the 2010 SEG Honorary Lecturer for Central and South America. My special gratitude to the Distinguished Lecture Committee and those who suggested and/or approved my nomination for this huge responsibility. I tried to do my best in each presentation. My sincere appreciation to Judy Wall of the SEG staff who put together the conditions that made me feel comfortable in each trip and for her impressive organization of all the people involved with each presentation. Her hard work contributed to a successful agenda over 5 weeks, 22 presentations, and 28 flights (to such places as Puerto Rico, Colombia, Venezuela, Brazil, Argentina, Chile, and Peru). Several more lectures were later presented in Mexico. I thank Shell for its sponsorship of this regional program of lectures which allows closer technical communication among audiences of common cultures and, finally, I thank Pemex Exploracion y Produccion for the knowledge earned through more than 20 years of technical projects and R&D programs, and for allowing me to use some proprietary material in this SEG Honorary Lecture.
Memorials
Authors: Aminzadeh Fred , Bresnahan Claire , Cramer Diana
Published: November 2012

Memorials for: Les Edwards Joy J. Anneler Arthur Cramer Jr. 1934–2009
The magic of Lamé
Authors: Goodway Bill
Published: November 2012

Early in 2009 I got a call from Greg Partyka informing me of my selection as the 2009 SEG Honorary Lecturer for North America. I felt extremely honored, even surprised in having been selected, but then some trepidation started to set in about what I had got myself into and if I was up to the task. However, over the following months my colleague Dave Mackidd, through a feeling of justifiable responsibility after having nominated me, helped put together my lecture with the somewhat intriguing title “The magic of Lamé.” By the time I was ready to start the tour, I had gathered examples from nearly 15 years of applying AVO inversion methods to E&P drilling challenges. Given the resulting length of the lecture, I must apologize to some of my audience who could be forgiven for thinking that the material had been accumulating since Gabriel Lamé's original lectures in eighteenth century Paris!
Signals
Authors: Stork Christof , Spies Brian
Published: November 2012

Signals are letters to the editor submitted by readers of The Leading Edge.
Planting seeds of opportunity: Directors speak up about giving back
Authors: Young Brian K.
Published: November 2012

You've read our message in The Leading Edge and Carrying the Torch. You've heard us repeat that message during the SEG Annual Meeting: Make a difference … pay it forward. You may have asked yourself, how can I make a difference? I'm just one person. Peter Duncan, past president of SEG (2004) and currently a director on the SEG Foundation Board, perhaps said it best: “The SEG Foundation is great only because of the efforts of individuals. One idea, one vision, one donation of time or money is where it all starts. The Foundation is a sum of ones.”
2011 SEG/EAGE DISC
Authors: Clark Dean
Published: November 2012

The 2011 Distinguished Instructor Short Course deals with seismic acquisition as a consequence of recent and dramatic acceleration in the evolution of the technology (e.g., wide-azimuth surveys offshore, vastly increased channel count onshore). The course, “Seismic acquisition from yesterday to tomorrow,” will be taught by Julien Meunier, geophysical advisor of the Land Acquisition product line of CGGVeritas. He previously spent 13 years as head of the company's research and development team for land acquisition.
SEAM Update
Authors: Fehler Michael
Published: November 2012

SEAM is continuing its effort to obtain a full suite of geophysical simulations over the SEAM Phase I Deepwater model. Isotropic acoustic, controlled-source electromagnetic (CSEM), and gravity simulations have been completed. We are now conducting acoustic simulations on an anisotropic version of the SEAM model.
Reviews
Authors: Taylor Patrick , Green William R.
Published: November 2012

Mantle Convection for Geologists, by G. F. Davies, ISBN 978-0-521-19800-4, Cambridge University Press, 2011, 232 pp., US $60. Remote Sensing and Global Environmental Change, by S. Purkis and V. Klemas, ISBN 978-1-4051-8225-6, Wiley-Blackwell Publications, 2011, 384 pp., hardcover US $159.95, paperback $89.95, electronic version available. Thermodynamics of the Earth and Planets, by A. P. Douce, ISBN 978-0-521-89621-4, Cambridge University Press, 2011, 709 pp., US $90.
Announcements
Authors: Pellerin Louise , Bradford John H.
Published: November 2012

This article provides news of recent past or upcoming SEG activities.
State of the Net
Authors: Posey Chris
Published: November 2012

In February, SEG launched the new “SEG Wiki—An Encyclopedia for Applied Geophysics.” Breaking new ground in the geosciences industry, the SEG Wiki is designed to serve up technical content to meet the needs of researchers worldwide. This specialized content can be found on the SEG Web site at wiki.seg.org . This new tool provides numerous benefits to geophysicists at all levels of the industry; four of these benefits are discussed below.
President's Page
Authors: Hardage Bob
Published: November 2012

Elsewhere in this issue, Dean Clark poses questions to me that probe into how SEG has changed over the 30-year lifetime of TLE and how it appears SEG will change in the near future. One of those questions deserves more comment than what I said to Dean; i.e., the question about the business philosophy that SEG is moving toward with regard to national and international meetings. Today as SEG plans and executes any type of meeting, whether large or small, we are finding intersociety cooperation necessary to ensure the targeted meeting is effective, attracts a proper type and size of crowd, and appeals to exhibitors. This increasing spirit of intersociety cooperation affects aspects of SEG other than just the number of meetings we schedule and the recruitment of sponsors for those meetings. Intersociety cooperation also impacts our conferences, workshops, honorary lectures, continuing education programs, and publications.
President's Page
Authors: Miller Rick
Published: November 2012

With the new governance structure approved, inaugural Board elections under way, and the Council converging on and strengthening its position as the unified voice of the membership, this feels like a good time to sit back and marvel at what our Society has accomplished. In actuality, this early stage in implementing the new governance is an opportune time to identify additional benefits that might be garnered through subtle enhancements to the new governance model. “While the iron is hot” is the right time to take a high-resolution look forward, tweak the Society's far-reaching vision, and shore up the excellent ground work already laid. The singular goal: optimally position our Society to effectively capitalize on future global opportunities.
President's Page
Authors: Abriel Bill
Published: November 2012

I'd like to spend this opportunity to write about the Geo in geophysics. Our profession incorporates a range of expertise—from theoretical physics to seismic mapping to supercomputing. The main thrust of our efforts is in support of Earth science decisions—it's all about the geology. So naturally, geophysicists must be reasonably good geologists to work effectively. As scientists in the remote-sensing profession, we use physics tools to predict the geology of the subsurface. It is a satisfying moment when the predictions we make are verified and disappointing when they are not.
Sections/Associated Societies Focus
Authors: Charoenthanwa Natthawut
Published: November 2012

The Thailand Society of Exploration Geophysicists (TSEG) was born on 7 July 2009 when the SEG Executive Committee officially approved the affiliation of TSEG as an SEG Section/Associated Society. In its three years of operation, TSEG has increased SEG's presence in Thailand by annually hosting the Distinguished Lecturers (DL), Honorary Lecturers (HL), and Distinguished Instructor Short Course (DISC), and by assisting in the creation of three student chapters (for a current total of four in Thailand).
Reviews
Authors: Bartel David C. , Avakian Bob , Green William R. , Avakian Bob , Green William R. , Sandham William A. , Moon Wooil M.
Published: November 2012

Elements of seismic dispersion: A somewhat practical guide to frequency-dependent phenomena, by C. L. Liner, ISBN 978-1-56080-291-4, SEG, Distinguished Instructor Short Course 15, 2012, 179 pp., US $58 (members $45, electronic version available). Introducing volcanology: A guide to hot rocks, by D. Jerram, ISBN 978-1-906716-22-6, Dunnedin Academic Press, 2011, 160 pp., US $19.95. Tsunami fingerprints in different archives—Sediments, dynamics and modelling approaches—Proceedings of the 2nd International Tsunami Field Symposium, September 22–28, 2008, in Ostuni (Italy) and Lefkada (Greece), G. Mastronuzzi, H. Brückner, P. Sansó, and A. Vött, eds., ISSN 0372-8854, Gebruder Borntraeger, Annals of Geomorphology, vol. 54, Supplementary Issue 3, 2010, 356 pp., €145. Volcanic earthquakes and tremor in Japan, by T. Nishimura and M. Iguchi, ISBN 978-4876989799, Koyoto University Press, 2011, 276 pp., US $79.95. Timescales of magmatic processes: From core to atmosphere, A. Dossetto, S. P. Turner, and J. A. Van-Orman, eds., ISBN 978-1-4443-3260-5, Wiley Blackwell, 2011, 264 pp., US $164.95 (hardback) $109.95 (paperback), electronic version available. Computer processing of remotely-sensed images: An introduction (4th ed.) by P. M. Mather and M. Koch, ISBN 978-0-470-74238-9, Wiley-Blackwell, 2010, 460 pp., US $99.95, £39.95, €48.00, electronic version available. Geographic Information Systems and Science, 3rd ed., P. A. Longley, M. F. Goodchild, D. J. Maguire, and D. W. Rhind, ISBN 978-0-470-72144-5, John Wiley & Sons, Inc., 2011, 539 pp., US $96.95.
President's Page
Authors: Beydoun Wafik
Published: November 2012

My previous contribution to the President's Page seems so recent (May 2012) that I have the impression I'm monopolizing your attention. Reserves estimation, the theme of the special section in this issue of TLE, is so far-reaching that I would like to address this topic here as a short foreword to the introduction by R. Lorenzen, H. J. Kloosterman, and W. Abriel.
Reviews
Authors: McCormack Michael
Published: November 2012

Seismic Imaging and Inversion: Application of Linear Inverse Theory, by R. H. Stolt and A. B. Weglein, ISBN 978-1-107-01490-9, Cambridge University Press, 2012, 404 pp., US $125.
State of the Net
Authors: Posey Chris
Published: November 2012

In the March 2012 issue of The Leading Edge, we told you about the much-anticipated rollout of the SEG Wiki and the ways you can benefit from it: The SEG Wiki is a simple, intuitive research tool; The SEG Wiki focuses exclusively on geosciences topics; The SEG Wiki is moderated by your peers; The SEG Wiki is populated by your peers … and Sheriff's Encyclopedic Dictionary of Applied Geophysics, fourth edition.
President's Page
Authors: Monk Dave
Published: November 2012

When I last wrote a President's Page, I pondered the issue of diversity within (and of) our Society. At the time, the nominees for the 2012–2013 Board of Directors were not known, and the results of these elections were in the future. I stressed my hope that the membership would elect “highly qualified, dedicated candidates, recognized by their peers,” and that I would serve with a Board that was the “cream of the crop.” I had no idea exactly how the Board would be made up, how diverse it would be, and what the caliber and pedigree of the Board members might be.
Quantitative interpretation of the McKay oil sands thermal area: Canadian case study
Authors: Bellman Laurie M. Weston , Knowles Amanda , Pak Rozalia
Published: November 2012

Southern Pacific Resource Corporation (STP) acquired 211 km of 2D seismic data in September 2007 and an additional 5.1 km2 of 3D in December 2010. The 2D survey was used as an exploration tool, which ultimately lead to the McKay Thermal Project in northeastern Alberta. Conventional seismic interpretation has been valuable in defining the structure and regional extent of the reservoir. However, the conventional seismic character lacks the detail or consistency to delineate subtle facies variations present in the reservoir. Risk reduction through increased understanding of the reservoir at this stage of an oil sands project has the potential for significant benefits as the project moves on to production. Seismic data have already proven beneficial in the evaluation phase of this project; the intent with this case study was to investigate the potential to derive more detailed information from the seismic about the reservoir character and fluid content using quantitative interpretation (QI) techniques.
Relationship of total 25-OH vitamin D concentrations to Indices of Multiple Deprivation: geoanalysis of laboratory results
Authors: Webster Craig
Published: November 2012

Background

Vitamin D deficiency appears to be widespread and associated with ethnicity and economic status. Geography is the key to virtually all national statistics. It provides a structure for collecting, processing, storing and aggregating data. Linking geographic data to laboratory data allows analysis of the association of laboratory data with economic indicators.

Methods

The laboratory information system was searched to create a data-set of total 25-OH vitamin D concentrations, which was then linked to economic (Indices of Multiple Deprivation [IMD]) and ethnicity data using postcodes geocoded to Lower Super Output Areas (LSOAs).

Results

A total of 12422 25-OH vitamin D requests were received during the time period searched. A total of 12167 of these had associated postcodes that would allow georeferencing to LSOAs. The median total 25-OH vitamin D was 24.5 nmol/L (5.3-99.0; 2.5-97.5th percentile). Statistically significant (Spearman rank) correlations were found between median 25-OH vitamin D (nmol/L) and percentage of non-White population and percentage of non-White population and IMD. No statistically significant correlation between median 25-OH vitamin D concentration and IMD was found; however, a statistically significant correlation between percentage of population classified as severely deficient and IMD was found.

Conclusions

In summary, vitamin D deficiency is widespread and is related to ethnicity; it does not appear to be related to economic status except in cases of severe vitamin D deficiency.
The association of a La module with the PABP-interacting motif PAM2 is a recurrent evolutionary process that led to the neofunctionalization of La-related proteins
Authors: Merret Rémy , Martino Luigi , Bousquet-Antonelli Cécile , Fneich Sara , Descombin Julie , Billey Élodie , Conte Maria R. , Deragon Jean-Marc
Published: November 2012

La-related proteins (LARPs) are largely uncharacterized factors, well conserved throughout evolution. Recent reports on the function of human LARP4 and LARP6 suggest that these proteins fulfill key functions in mRNA metabolism and/or translation. We report here a detailed evolutionary history of the LARP4 and 6 families in eukaryotes. Genes coding for LARP4 and 6 were duplicated in the common ancestor of the vertebrate lineage, but one LARP6 gene was subsequently lost in the common ancestor of the eutherian lineage. The LARP6 gene was also independently duplicated several times in the vascular plant lineage. We observed that vertebrate LARP4 and plant LARP6 duplication events were correlated with the acquisition of a PABP-interacting motif 2 (PAM2) and with a significant reorganization of their RNA-binding modules. Using isothermal titration calorimetry (ITC) and immunoprecipitation methods, we show that the two plant PAM2-containing LARP6s (LARP6b and c) can, indeed, interact with the major plant poly(A)-binding protein (PAB2), while the third plant LARP6 (LARP6a) is unable to do so. We also analyzed the RNA-binding properties and the subcellular localizations of the two types of plant LARP6 proteins and found that they display nonredundant characteristics. As a whole, our results support a model in which the acquisition by LARP4 and LARP6 of a PAM2 allowed their targeting to mRNA 3′ UTRs and led to their neofunctionalization.
Golden Merganser Story Promenade: A case study of oral multilingual storytelling strategies
Authors: Aaltonen Heli
Published: November 2012

This case study illustrates how multilingual storytelling strategies were investigated in the context of ‘Golden Merganser: Story Promenade’ on 1 October 2011 in the City of Turku. Experiments in oral multilingual storytelling represent an intercultural practice. The artistic work was informed by Guattari’s critical theory of three ecological registers. The storytellers investigated multilingual storytelling strategies through artistic work. The outcome of the project suggests that the essence of telling a narrative is to experience the world of the narrative. The multilingual storytellers need to establish the same world, dream the same dream, make dramaturgical work, and engage in music improvisation with different languages. Multilingual storytelling practice helps to encounter foreign languages with curiosity and interest and offer possibilities for strengthening multilingual identity construction.
Creating notebooks, photographs and interventions: Visualizing African, Caribbean and Arabic presence in Europe
Authors: Kempadoo Roshini
Published: November 2012

The article explores the way in which African, Caribbean and Arabic European presence is visualized by diasporic women artists. With histories associated with recent migration to Europe by persons from non-European, Southern backgrounds, perceptual practice is presented as partial and
feminist. The article makes explicit the perceptions, perspectives and viewpoints we are positioned by as persons associated with the postcolonies making claims of identity in Europe. Charting a historical trajectory of cultural politics, aesthetics and activism associated with photography
and film, I explore the artworks in relation to aesthetics, tropes and techniques. The work will be contextualized within recent popular media images and perceptions of African and Arab migration by the European press. The artworks explored here are imaginary inscriptions whose starting point
alludes to migratory routes and journeying – often initial experiences in developing a sense of belonging. I present my own recent screen/photography installation Arrival (2010) and include works by Yto Barrada, and Berni Searle. They evoke critical perspectives that talk back, emerging
from long histories of counter-narration that make meanings of blackness that engage with the gaze outwards from postcolonial spaces and diasporic subjects, as well as from the look back.
Katrina’s city? New Orleans, race, myth, forced migration and return
Authors: Doughty Ruth
Published: November 2012

Hurricane Katrina was responsible for the displacement of the entire city of New Orleans. This article will consider the forced migration of the city’s inhabitants, focusing specifically on poor African Americans. In the aftermath, families were separated and relocated all across
the United States, controversially referred to as ‘refugees’. This problematically evokes Harold Cruse’s idea of ‘domestic colonies’ as it aligns black identity with the notion of foreignness. The imposed dislocation of black American families cannot be divorced
from the historical context of slavery; the image of the migrant wading through the water evokes stories of fugitive slaves taking to the Mississippi River in an attempt to escape capture. The evacuation was in part due to an inherently racist infrastructure, primarily and irrefutably based
on class. Yet, in spite of this, many citizens chose to return. The article will consider the homecoming experience in relation to the mythical status of the city and its rich cultu al heritage; how the ‘pull’ factors outweighed the political and socio- economic realities. Using
the documentaries, When the Levees Broke: A Requiem in Four Acts (Lee, 2006), and Trouble the Water (Deal and Lessin, 2008) along with the HBO series Treme (2010–2011), this article will explore forced migration and intransigence, the image of the migrant, and the narrative of return
in relation to African American identity, mythology, history, race and class.
REVIEWS
Authors: East Jessica , Laursen Ole Birk
Published: November 2012

GENDER, RELIGION, AND MIGRATION: PATHWAYS OF INTEGRATION, GLENDA TIBE BONIFACIO AND VIVIENNE SM. ANGELES (EDS) (2010) Maryland: Lexington Books, 304 pp., ISBN 978-0739133132, h/bk, £ 47.45; p/bk, £ 21.80

BRITISH MUSLIM FICTIONS: INTERVIEWS WITH CONTEMPORARY WRITERS, CLAIRE
CHAMBERS(2011) Basingstoke: Palgrave Macmillan, 368 pp. ISBN: 978-0230308787, Hardback, £55.00; Paperback, £18.04
Life in the bubble: The leisure experiences of female Swedish seasonal hospitality workers in Nordkapp, Norway
Authors: Heimtun Bente
Published: November 2012

This article examines how female Swedish seasonal hospitality workers in Norway negotiate migrant living. ‘A posteriori’ it sets out to explore how the bubble lives constructed by many of the female workers are shaped by the Arctic location and lack of local contact zones,
and are mainly upheld by their financial motives for taking the job. The difference of climate, natural surroundings and townscape, for instance, confines some of them to their temporarily rented rooms. The experienced transnational workers are less affected by difference and enjoy a more
active lifestyle. Moreover, the midnight sun gives the women a sense of timelessness that disturbs their daily rhythm. This makes some of the women passive and sleepy, whereas others gain energy and do unexpected things. It is argued that the women’s construction of bubble lives is not
so much about difference of place and timelessness, but rather their lack of ability to transfer earlier embodied senses of presence and time to the new community and location. Often secluded in a planted enclave, they do not learn about the Arctic and Arctic living. They thus remain in the
bubble.
Critically unpacking professionalism in hospitality: Knowledge, meaningful work and dignity
Authors: Cockburn-Wootten Cheryl
Published: November 2012

Calls for change within the hospitality sector have argued for the industry to seriously consider the implementation of professionalism. Concerns have been raised about the workplace conditions of many employees, the readiness of graduates to meet or challenge these practices, and commitment
to sustainability in promoting and respecting the rights of people in the workplace. In this conceptual article traditional perspectives of professionalism are critically examined. A key argument is that recent changes to professionalism have transformed the term into another discursive tool
for discipline, performance and control. Rather than focusing on professionalism this article asserts that the sector should seriously consider implementing meaningful work and dignity. The article concludes that integrating these concepts through practices such as caring relationships, trust
and education of managers starts to open up avenues for change in this hostile industry. Overall, the article argues that by adopting a broader understanding of professionalism, one that incorporates communication and collaboration, and challenges the lack of dignity in the workplace, we can
start to open up possibilities for interdisciplinary work and more importantly, change.
Television consumption trends among the ‘digital generation’ in Spain
Authors: Aldea Patricia González , Vidales Nereida López
Published: November 2012

The development of new technologies is changing the habits of television consumption among young people. The multiplication of channels has intensified the fragmentation of the market and its audiences and the individualist atomization in the media preferences and consumption. This
article is part of a research project aiming to establish television consumption preferences, opinions and habits of Spanish young people, aged between 14 and 25 years, and the differences between the two groups into which the respondents were divided (14–17 and 18–25). The article
shows the extent to which Spanish youngsters have turned to new media as a source of entertainment.Indeed, one of the most groundbreaking results that should be highlighted is the difference between the two groups in their approach to the Internet as a source of entertainment.The article shows
how the digital generation demands the adaptation of television content to the new platforms – such as the Internet or mobile phone – and the renewal of television formats. The findings of this study also point to trend indicators and guidelines that advertisers and media companies
might be interested in when designing new creative and innovative television content.
The politics of vocational training of industrial technicians in Spain, 1924–30
Authors: Gómez M. Luisa Rico
Published: November 2012

In this study, I examine the extent to which technical education served to form a new middle class of industrial technicians during the dictatorship of Primo de Rivera in Spain. The principal means of achieving this, the Industrial Education Statute of 1924 and the Vocational Training
Statute of 1928, were aimed at the working classes and the petty bourgeoisie. The intention was that both groups would support the State’s social and corporative system whilst at the same time promoting the country’s modernization. The great gap between economic and social reality,
however, led to the failure of this educational project.
La actitud ética de los periodistas españoles frente a los conflictos de intereses
Authors: Domínguez Lorena R. Romero , Villegas Juan Carlos Suárez
Published: November 2012

El presente artículo muestra los resultados obtenidos en el Proyecto de Investigación ‘Ética informativa y excelencia: la deontología periodística frente a las expectativas de la ciudadanía’, desarrollado por las universidades Pompeu
Fabra (Barcelona), Carlos III (Madrid), Universidad del País Vasco y Universidad de Sevilla. El objetivo de la investigación, financiada por el Ministerio de Educación y Ciencia (Plan Nacional de I+D+I 2004–2007), consistió en analizar las actitudes de los
profesionales de la información al objeto de contrastar cómo factores ajenos a la información pueden afectar su rutina productiva. Para el presente artículo nos hemos centrado en los conflictos de intereses, analizando, por un lado, la actitud de los periodistas
frente a los regalos y otros beneficios obtenidos de su fuente; y, por otro, explicando la relación del profesional con las compañías que se anuncian en los medios de comunicación.
The living rooms our city-centres ought to be: Olohuone an urban experiment in Helsinki Railway Station
Authors: Galanakis Michail
Published: November 2012

Olohuone is the Finnish word for living room, as well as the name I gave a publicly accessible installation that I made on the basis of art and action research. I will briefly describe the context of the installation, and then proceed to analyse it as an urban intervention,and finally offer the findings produced by the entire process. Keith Hoggart and colleagues write that ‘Action Research is associated with learning about society through efforts to change it’. Olohuone was part of my action research and a fundamental component of my doctoral dissertation. In it, I framed a situation at a busy urban space and, in so doing, I intervened and temporarily changed the field of my study. Olohuone proved to be a critical case study for my research, mainly because of the responses of the people who interacted with it. In these years since Olohuone, I have lectured about it on numerous occasions. When I talk about Olohuone, the reactions I get encourage me to keep on using it as an example of place-making and of research in urban studies. During lectures, I discover aspects of Olohuone that I have not thought of before, often due to the questions posed by students. This is why I think that my findings from Olohuone merit consideration in relation to action in art and design research, place-making and intercultural dialogue.