bluuebunny/crossref_metadata_2025 huggingface dataset:
Penyuluhan Ilmu Pengetahuan dan Teknologi Tepat Guna Dalam Meningkatkan Ekonomi Desa di Kabupaten Kepulauan Meranti
Authors: Syawaldi  , Hastuti Kurnia
Published: May 2020

Kegiatan Pengabdian kepada masyarakat yang berjudul Ilmu Pengetahuaan  dan Teknologi Tepat  Guna (TTG)  telah  dapat  dilaksanakan  dengan  baik  dan  sesuai  dengan  target  yang dirapkan. Dimana kegiatan pengabdiaan kepada masyarakat dilaksanakan 18 – 20 Oktober 2019.  Kegiatan pengabdian  kepada  masyarakat  adalah  kerjasama  dengan  Badan Pemberdayaan  Masyarakat  dan  Desa.  Dimana  Universitas  Islam  Riau  melalui  Fakultas merasa  terpanggil   dalam  rangka   mencerdaskan   masyarakat   tentang  ilmu  pengetahuan teknologi  tepat guna (TTG).  Ilmu pengetahuan  teknologi  tepat guna merupakan  hal  yang sangat penting dalam pembangunan dan ekonomi pedesaan. Salah satu desa Bina Maju Kecamatan rangsang barat Kabupaten Kepulauan Meranti, dimana  potensi sumber daya alam dan sumber sangat baik. Maka dari itu perlu membangun kreativitas dalam upaya untuk bisa bertahan dimasa yang akan dating. Salah satunya ilmu pengetahuan  dan teknologi tepat guna salah satu alternatif untuk menyelesaian  masyarakat  di Desa saat ini. Selain itu, pembangunan  dan ekonomi pedesaan yang berdasarkan usaha masyarakat perlu dimotivasi dan dikembangkan melalui teknologi berupa teknologi tepat guna. Untuk pengembangan  teknologi tepat guna perlu upaya dan kerja masyarakat membuat teknologi tepat guna yang sesuai dengan potensi yang ada dimasyarakat itu sendiri. Maka dosen teknik mesin Fakultas teknik universitas islam riau bekerjasama dengan badan pemberdayaan masyarakat dan desa (PMD) kepulauan meranti memberikan pengajaran tentang ilmu pengetahuan teknologi tepat guna. Dengan tujuan kedepannya dapat meningkatkan  sumber daya manusia (SDM) dalam pembuatan teknologi tepat guna untuk meningkatkan ekonomi masyarakat dan desa.
The SIR dynamic model of infectious disease transmission and its analogy with chemical kinetics
Authors: Simon Cory
Published: May 2020

Mathematical models of the dynamics of infectious disease transmission are used to forecast epidemics and assess mitigation strategies. We reveal that the classic Susceptible-Infectious-Recovered (SIR) epidemic model resembles a dynamic model of a batch reactor carrying out an autocatalytic reaction with catalyst deactivation. This analogy between disease transmission and chemical reactions allows chemists and chemical engineers to peer into dynamic models of infectious disease transmission and gives insights into the kinetics of autocatalytic reactions.
Targeting TMPRSS2 and Cathepsin B/L Together May Be Synergistic Against SARS-CoV-2 Infection
Authors: Padmanabhan Pranesh , Desikan Rajat , Dixit Narendra
Published: May 2020

The entry of SARS-CoV-2 into target cells requires the activation of its surface spike protein, S, by host proteases. The host serine protease TMPRSS2 and cysteine proteases Cathepsin B/L can activate S, making two independent entry pathways accessible to SARS-CoV-2. Blocking the proteases prevents SARS-CoV-2 entry in vitro. This blockade may be achieved in vivo through ‘repurposing’ drugs, a potential treatment option for COVID-19 that is now in clinical trials. Here, we found, surprisingly, that drugs targeting the two pathways, although independent, could display strong synergy in blocking virus entry. We predicted this synergy first using a mathematical model of SARS-CoV-2 entry and dynamics in vitro. The model considered the two pathways explicitly, let the entry efficiency through a pathway depend on the corresponding protease expression level, which varied across cells, and let inhibitors compromise the efficiency in a dose-dependent manner. The synergy predicted was novel and arose from effects of the drugs at both the single cell and the cell population levels. Validating our predictions, available in vitro data on SARS-CoV-2 and SARS-CoV entry displayed this synergy. Further, analysing the data using our model, we estimated the relative usage of the two pathways and found it to vary widely across cell lines, suggesting that targeting both pathways in vivo may be important and synergistic given the broad tissue tropism of SARS-CoV-2. Our findings provide insights into SARS-CoV-2 entry into target cells and may help improve the deployability of drug combinations targeting host proteases required for the entry.
An Integrated Microfluidic Probe for Mass Spectrometry Imaging of Biological Samples
Authors: Li Xiangtang , yin ruichuan , hu hang , Li Yingju , Sun Xiaofei , Dey Sudhansu , Laskin Julia
Published: May 2020

Ambient ionization based on liquid extraction is widely used in mass spectrometry

imaging (MSI) of molecules in biological samples. The development of nanospray desorption electrospray ionization (nano-DESI) has enabled the robust imaging of tissue sections with high spatial resolution. However, the fabrication of the nano-DESI probe is challenging, which limits its dissemination to the broader scientific community. Herein, we describe the design and performance of an integrated microfluidic probe (iMFP) for nano-DESI MSI. The glass iMFP fabricated using photolithography, wet etching, and polishing shows comparable performance to the capillary-based nano-DESI MSI in terms of stability and sensitivity; the spatial resolution of better than 25 μm was obtained in these first proof-of-principle experiments. The iMFP is easy to operate and align in front of a mass spectrometer, which will facilitate broader use of liquid extraction-based MSI in biological research, drug discovery, and clinical studies.
Ritonavir May Inhibit Exoribonuclease Activity of Nsp14 from the SARS-CoV-2 Virus and Potentiate the Activity of Chain Terminating Drugs
Authors: narayanan naveen , nair deepak t
Published: May 2020

SARS-CoV-2 is the causative agent for the ongoing COVID19 pandemic, and this virus belongs to the Coronaviridae family. The nsp14 protein of SARS-CoV-2 houses a 3’ to 5’ exoribonuclease activity responsible for removing mismatches that arise during genome duplication. A homology model of nsp10-nsp14 complex was used to carry out in silico screening to identify molecules among natural products, or FDA approved drugs that can potentially inhibit the activity of nsp14. This exercise showed that ritonavir might bind to the exoribonuclease active site of the nsp14 protein. A model of the SCV2-nsp10-nsp14 complexbound to substrate RNA showed that the ritonavir binding site overlaps with that of the 3’ nucleotide of substrate RNA. A comparison of the calculated energies of binding for RNA and ritonavir suggested that the drug may bind to the active site of nsp14 with significant affinity. It is, therefore, possible that ritonavir may prevent association with substrate RNA and thus inhibit the exoribonuclease activity of nsp14. Overall, our computational studies suggest that ritonavirmay serve as an effective inhibitor of the nsp14 protein. nsp14 is known to attenuate the inhibitory effect of drugs that function through premature termination of viral genomereplication. Hence, ritonavir may potentiate the therapeutic properties of drugs such as remdesivir, favipiravir and ribavirin.
Optimization of a New Reactive Force Field for Silver - Based Materials
Authors: Dulong Clément , Madebène Bruno , Monti Susanna , Richardi Johannes
Published: May 2020

A new reactive force field based on the ReaxFF formalism is effectively parametrized against an extended training set of quantum chemistry data (containing more than 120 different structures) to describe accurately silver- and silver-thiolate systems. The results obtained with this novel representation demonstrate that the novel ReaxFF paradigm is a powerful methodology to reproduce more appropriately average geometric and energetic properties of metal clusters and slabs when compared to the earlier ReaxFF parametrizations dealing with silver and gold. ReaxFF cannot describe adequately specific geometrical features such as the observed shorter distances between the under-coordinated atoms at the cluster edges. Geometric and energetic properties of thiolates adsorbed on a silver Ag20 pyramid are correctly represented by the new ReaxFF and compared with results for gold. The simulation of self-assembled monolayers of thiolates on a silver (111) surface does not indicate the formation of staples in contrast to the results for gold-thiolate systems.
Isolating the Role of the Node-Linker Bond in the Compression of UiO-66 Metal-Organic Frameworks
Authors: Redfern Louis , Ducamp Maxime , Wasson Megan C. , Robison Lee , Son Florencia , Coudert François-Xavier , Farha Omar
Published: May 2020

Understanding the mechanical properties of metal–organic frameworks (MOFs) is essential to the fundamental advancement and practical implementations of porous materials. Recent computational and experimental efforts have revealed correlations between mechanical properties and pore size, topology, and defect density. These results demonstrate the important role of the organic linker in the response of these materials to physical stresses. However, the impact of the coordination bond between the inorganic node and organic linker on the mechanical stability of MOFs has not been thoroughly studied. Here, we isolate the role of this node–linker coordination bond to systematically study the effect it plays in the compression of a series of isostructural MOFs, M-UiO-66 (M = Zr, Hf, or Ce). The bulk modulus (i.e. the resistance to compression under hydrostatic pressure) of each MOF is determined by in situ diamond anvil cell (DAC) powder X-ray diffraction measurements and density functional theory (DFT) simulations. These experiments reveal distinctive behavior of Ce-UiO-66 in response to pressures under one GPa. In situ DAC Raman spectroscopy and DFT calculations support the observed differences in compressibility between Zr-UiO-66 and the Ce- analogue. Monitoring changes in bond lengths as a function of pressure through DFT simulations provides a clear picture of those which shorten more drastically under pressure and those which resist compression. This study demonstrates that changes to the node–linker bond can have significant ramifications on the mechanical properties of MOFs.
De Novo Design of a Nanopore for DNA Detection Incorporating a β-hairpin Peptide
Authors: Shimizu Keisuke , Mijiddorj Batsaikhan , Yoshida Shuhei , Akayama Shiori , Hamada Yoshio , ohyama akifumi , Usui Kenji , Kawamura Izuru , Kawano Ryuji
Published: May 2020

The amino acid sequence of a protein encodes information on its three-dimensional structure and specific functionality. De novo protein design has emerged as a method to manipulate the primary structure for the development of artificial proteins and peptides with desired functionality. This paper describes the de novo design of a pore-forming peptide that has a β-hairpin structure and assembles to form a stable nanopore in a bilayer lipid membrane. This large synthetic nanopore is an entirely artificial device with practical applications. This peptide, named SV28, forms nanopore structures ranging from 1.6 to 6.2 nm in diameter assembled from 7 to 18 monomers. The nanopore formed with a diameter of 5 nm is able to detect long double-stranded DNA (dsDNA) with 1 kbp length, and measurement of current signals allowed us to investigate the translocation behavior of dsDNA at the single molecule level. Such de novo design of peptide sequences has the potential to create assembled structure in lipid membrane such as novel nanopores, which would also be applicable in molecular transporter between inside and outside of lipid membrane.
Momentum Relaxed, Plasmon-Resonant Vibrational Sum Frequency Generation of Electrochemical Interfaces: Direct Observation of Carbon Dioxide Electroreduction on Gold
Authors: Wallentine Spencer , Bandaranayake Savini , Biswas Somnath , Baker L. Robert
Published: May 2020

We present a vibrational sum frequency generation method to probe the Au/electrolyte interface with a detection limit of < 1% of a monolayer, and with currents exceeding 1 mA/cm2 during CO2 reduction. We couple light to the interface using momentum relaxed surface plasmon resonance. Using this technique we make in-situ measurements of catalytic CO with good signal-to-noise and at high current density.
Evolution, Ayurveda, immunity, and preventive aspects for emerging infectious diseases such as COVID-19
Authors: Rajput Dhirajsingh Sumersingh
Published: May 2020

Evolution is continuous process of changes in structural and physiological mechanism in living being. Microbes/pathogens can evolve naturally or artificially and become resistant to various medicines. Novel coronavirus is such evolved pathogen of coronavirus group. Enough strong immunity is needed to prevent or survive from COVID-19 pandemic. Ayurveda provides ways for evolving physiological responses to built immunity. Present work is brief attempt to increase insight in this filed.Present review was done based on simple theory of evolution, recent updates regarding prevention of COVID-19, Ayurveda aspect toward infectious diseases and Ayurveda ways towards prevention of infectious diseases with special reference to COVID-19. Person with impaired immunity is more susceptible for COVID-19 and thus immunity is an important preventing factor. Ayurveda Rasayana (rejuvanation) herbs, Yoga exercises, Pranayama (special breathing exercise), daily regimens and personal hygiene guidelines can be helpful strategies in controlling the spread of COVID-19.The preventive aspects of pandemic situations are narrated in Ayurveda with enough details. These ways need to be scientifically explored and refined for precision. As prevention is always better than cure hence Ayurveda ways can be considered for future strategies to avoid pandemics such as COVID-19.  There is great need of research on Ayurveda medicines on COVID-19 like diseases.
Mineral availability, dietary fiber contents, and short-chain fatty acid fermentation products of Caulerpa lentillifera and Kappaphycus alvarezii seaweeds
Authors: Alcantara James David S. , Lazaro-Llanos Nancy
Published: May 2020

Seaweeds like Caulerpa lentillifera and Kappaphycus alvarezii are used as main ingredients in Filipino delicacies. There is a need to investigate the mineral availability, dietary fiber contents, and short-chain fatty acid fermentation products of these Philippine seaweeds to assess its nutritional and health benefits. Results show that C. lentillifera contain higher levels of iron, zinc, and calcium (430.93 ± 1.46, 1.09 ± 0.19, and 988.44 ± 5.07 mg/100g, respectively) compared with K. alvarezii (11.34 ± 0.14, 0.29 ± 0.01, and 262.98 ± 2.83 mg/100g, respectively). The availability of calcium was shown to be higher in both seaweeds (94.10 - 96.45 %Ca) than iron and zinc availabilities. Both samples exhibited high amounts of dietary fibers. The soluble, insoluble, and total dietary fiber contents of K. alvarezii (16.73 ± 0.03, 42.24 ± 1.04, and 58.97 ± 1.01 g/100g, respectively) were higher than that of C. lentillifera (3.50 ± 0.41 g/100g for soluble, 27.17 ± 0.09 g/100g for insoluble, 30.67 ± 0.32 g/100g for total dietary fiber). In vitro fermentation using human fecal inoculum afforded short chain fatty acids (SCFA). The SCFA content analysis using HPLC showed that K. alvarezii produced propionate (35.53 ± 2.00 g/100g) and butyrate (3.19 ± 0.16 g/100g) SCFAs while C. lentillifera only produced propionate (15.92 ± 0.45 g/100g) SCFA suggesting the potential of these seaweeds for the prevention of some diseases.
Forbidden mourning: how COVID-19 threatens our collective memory
Authors: Lichtner Giacomo
Published: May 2020

This article reflects on a specific effect of the pandemic response: namely the impossibility of holding funerals. The article connects this especially grievous and emotional aspect to classical concepts of burial and the denial of burial, before arguing that the vulnerability of the elderly to Covi-19 poses an unprecedented threat to societies' collective memory.
Mixed-ligand coordination polymers: structural diversity and protective effect on cardiac arrest induced by anesthesia via inducing Sirt1 pathway
Authors: Xiao Q.-S. , Ren G.-Z. , Li J.-J. , Yin H. , Yu H. , Liu G.
Published: May 2020

A reaction of the N-donor ligand 1,3-di(1H-imidazol-1-yl)benzene (dimb) with Co(NO3)2·6H2O and the V-shaped carboxylate ligand biphenyl-3,4',5-tricarboxylic acid (H3bpt) under hydro- or solvothermal conditions yields two new Co(II)-based coordination polymers with the chemical formulas {Co3(dimb)2(bpt)2(H2O)4]}n (1) and [Co2(dimb)2(Hbpt)2]·H2O (2). Furthermore, the treatment effect of compounds 1 and 2 against cardiac arrest induced by anesthesia is evaluated. Firstly, ELISA is used to detect the content of cardiac troponin T and B brain natriuretic peptide after treatment with the compounds. Moreover, RT-PCR is conducted and the relative expression level of Sirt1 in the rat myocardial tissue is measured.
Two Co(II)-based coordination polymers: structural insights and stimulation activity on osteoblasts differentiation by increasing the Wnt/β-catenin signaling pathway activation
Authors: Shi L. , Feng J. , Zhang J. , Wang Q.
Published: May 2020

In this work, two Co(II)-based coordination polymers with the chemical formulae [CoCl(cptpy)·2H2O]n (1) and [Co2Cl2(cptpy)2(ma)H2O]n (2, Hcptpy = 4'-(4-carboxyphenyl)-2,2':6',2''-terpyridine, ma = melamine) are hydrothermally synthesized without or with employment of the template melamine. The as-prepared two complexes are studied via single crystal X-ray diffraction along with the elemental analysis. Furthermore, the protective ability of the compounds on the osteoblast differentiation is evaluated and the related detailed mechanism is explored. Firstly, the Western blot is used to detect the activation of the Wnt/β-catenin signaling pathway after treatment with the compounds. Next, the RT-PCR assay is used to measure the relative expression of indicators of vegf and vwf angiogenesis.
Two Co(II) and Zn(II) coordination polymers: structural characterization and anticancer activity against nasopharyngeal carcinoma
Authors: He Z.-X. , Zhang Z.-H. , Dong Y.-F. , Liu H.-G. , Sun S.-D. , Wang S.-Z.
Published: May 2020

By employing a mixed-ligand strategy, two new coordination polymers with the chemical formulae [Co(4-bptzh)(1,3-BDC)] (1) and [Zn(4-bptzp)(1,3-BDC)]n (2) are hydrothermally synthesized using two flexible bis(pyridyl-tetrazole) ligands (4-bptzh = 1,4-bis(5-(4-pyridyl)tetra­zolyl)hexane, 4-bptzp = 1,4-bis(5-(4-pyridyl)tetrazolyl)propane) and 1,3-benzenedicarboxylic acid (1,3-H2BDC). Both complexes are characterized by single crystal X-ray diffraction along with the elemental analysis. Furthermore, the inhibitory effect of compounds 1 and 2 against CNE-1 nasopharyngeal cancer cells are evaluated in vitro. Firstly, the antiproliferation activity of compounds 1 and 2 against cancer cells is assessed by the CCK-8 assay. Then, the cancer cell apoptosis is measured with the Annexin V-FITC/PI apoptosis assay by flow cytometry.
SENDING DRONE FLYING SPEED DATA USING ANDROID-BASED CLIENT SERVER METHOD
Authors: Putra Daewu Gus Bintara , Kusumaningrum Anggraini
Published: May 2020

Abstract - Drones as Unmanned Aerial Vehicle that are controlled using remote control are experiencing better development. The speed of the drone that cannot be accessed on the remote control can be determined through a client-server based application. The client side application, named Mydrone, is placed on the drone while on the server side, named Admin Drone, on earth. Mydrone and Admin Drone are applications made in this research based on andorid. This application on the client and server is used to monitor the speed of flying drones by using the Google Play Service library. Data sent from the client to the server in realtime by using Google Firebase. From the tests carried out it can be seen the speed of the drone when flying horisontal ly, while when flying vertically the speed is not detected. Battery capacity will also decrease when the speed of the drone gets faster, this is seen in the data when the speed is 8,741 km / h, the electricity demand taken from the battery is 31%.
Middle-upper quaternary deposits of the northern sector of the Patagonian continental slope contourite system (Southwestern Atlantic)
Authors: Murdmaa I. O. , Ivanova E. V. , Kazarina G. H. , Simagin N. V. , Roslyakov A. G. , Borisov D. G. , Nemchenko N. V.
Published: May 2020

Lithological and micropaleontological (planktonic and benthic foraminifers, diatoms) studies in four sediment cores revealed major patterns of lithostratigraphy and biostratigraphy of contourites and gravitites in the uppermost sediment layer within the depth range 3500–4300 m of the northern sector of the Patagonian continental slope contourite system. It is ascertained that in conditions of low terrigenous material supply from the land and high, although variable bottom contour current velocities of waters of Antarctic origin, hemipelagic calcareous nanno-foraminiferal ooze deposited in the Holocene over middleupper Pleistocene contourites in the southern part of the study area (cores AI–2609, AI–2610). The Holocene calcareous surface layer is absent in the northern part of the study area (cores AI–2611, AI–2612). Middle-Upper contourites and gravitites are unevenly enriched in diatoms and radiolarians here, up to formation of slightly siliceous-terrigenous diatomaceous mud. Reworked Neogene foraminifers and diatoms evidence for erosion of Neogene deposits bottom currents and gravity flows.
Incidence and clinicohematological profile of lymphomas in Southern Punjab Pakistan
Authors: Saleem Umera , Naveed Muhammad Asif , Batool Maria , Nadeem Khadija , Muhammad Samiullah  , Safdar Sohail
Published: May 2020

Background: Lymphomas are ranked as the sixth most common malignancy worldwide. Endorsing a significant impact on the health sector among the developing countries like Pakistan. The aim of the current study was to estimate the burden and clinicopathological features of lymphomas in one of the major referral centers in Southern Punjab Pakistan.

Methodology: A descriptive cross-sectional study was conducted at the Pathology department of Nishtar Medical University, Multan January 2016 to August 2019. A total of 74 patients both male and females of all age groups with diagnosed lymphoma were enrolled in the study. Diagnosis was made on morphology and immunohistochemistry of lymph node and cases with complete immunohistochemical workup were included and those without immunohistochemical panel were excluded from the study. Baseline tests were performed and bone marrow specimens were extracted from all cases. The data was analyzed using SPSS Version 23.0.

Results: Out of the total, 22.6% patients had Hodgkin lymphoma (HL) and 77.4% had Non-Hodgkin lymphoma (NHL). Classical Hodgkin lymphoma (CHL) was the most frequent histology (94%) among HL patients while Diffuse large B cell lymphoma (DLBCL) was the commonest B cell NHL (29.3%) and T cell lymphoblastic lymphoma (T-LBL) was found to be the most common T cell variant (5.3%). B symptoms, splenomegaly and hepatomegaly were documented in 96%, 42.7% and 25.3% patients respectively. Moreover, the disease was nodal in 65% cases and extranodal presentation was observed in 35% of the cases. Cervical node (lymph node) was involved in 25.3% of the cases while bone marrow was common among 53.3% cases. The patterns of bone marrow infiltration were para trabecular (24.3%), diffuse (22.5%), interstitial (1.8%) and mixed pattern (3.75%).

Conclusion: Lymphomas are relatively more common among younger population in Pakistan. NHLs constitute more than 2/3rd of all lymphomas with DLBCL as the commonest histology. Stage IV disease as evidenced by bone marrow infiltration is seen in more than half of our patients.
Evaluating nurses’ knowledge regarding dosage calculation at Civil Hospital, Karachi
Authors: Mangrio Abdul Rahim , Jokhio Pir Bux , Mahar Saif Ullah
Published: May 2020

Background: Appropriate therapeutic care and management is primarily based on the knowledge of dosage calculation and associated skills. The objective of this study was to determine the awareness of staff nurses working in a tertiary care hospital regarding the dose calculation.

Methodology: A pre-and post-test interventional study was conducted at a Civil Hospital, Karachi over a sample of 50 staff nurses working in different departments. The data was collected using an assessment tool containing 20 items to evaluate the drug dosage calculation skills and knowledge of the staff nurses. The assessment test was taken once initially after enrollment and then an extensive interventional training regarding the dosage calculation was provided to each nurse which was followed by a post intervention assessment test. The results were then rated on the basis of knowledge scores both before and after intervention i.e. 1-5 (poor), 6-10 (satisfactory), 11-15 (good) and 16-20 (excellent). Data was analyzed using SPSS Version 21.0.

Results: A total of 50 nurses participated in this study, of which 44% were males and 56% were females. The nurses had better knowledge both pre & post-test regarding the intravenous medication as compared to the oral for e.g. the nurses of neurosurgery department obtained a mean pre-test score of 4.2±0.8 (oral) and 10.1±2.4 (Intravenous), while the mean post -test were 4.7±0.7 (oral) and 14.6±0.7 (Intravenous). Another point of concern was the dosage calculation in pediatrics department was compromised both for oral and intravenous 2.8±1.7 (pre-oral) and 6.5±1.2 (post-intravenous) increased to 4.6±0.7(post-oral) and 13.6±1.8 (post-intravenous). Moreover, 18% of nurses had poor knowledge of dosage calculation as rated on the pre-test assessment while based on the post-test score none of the nurses had poor knowledge, majority was labeled as having improved knowledge of dosage calculation after interventional training.   

Conclusion: Overall, the study reveals that the majority of the staff nurses lack adequate knowledge and skills related to drug dosage calculations. There is a dire need for in-service education to enhance the knowledge and skills of staff nurses related to drug dosage calculations.
Young adults Undergoing Coronary Artery Bypass Grafting (CABG)
Authors: Muhammad Arif  , Saleem Yusra , Riaz Stephen , Mahapara  , Muhammad Imran  , Sharjeel Atif , Ali Khan Shujjaat , Khan Ghufranullah
Published: May 2020

Background: Coronary artery bypass grafting (CABG) is referred to as the gold standard therapeutic modality for treating coronary artery disease (CAD) among both old or young patients. hypertension, diabetes, Increased BMI and obesity, etc. are among the major risk factors for the development of cardiovascular diseases. The aim of the current study was to highlight the increasing rate of CAD and associated CABG surgery among young adults and to identify the potential risk factors associated with it.

Methodology: In this hospital based observational study, CAD patients ≤40 years of age admitted to the cardiac surgery department of a leading cardiac center for CABG surgery were included in the study. The study continued from 5th January 2018 to 21st August 2019 and the data of 184 patients who underwent CABG was collected during this time period. The details regarding patients' age, weight, height and body mass index (BMI) were obtained at the time of initial examination. Moreover, medical records, familial history and risk profile were also monitored. The collected data was analyzed using SPSS Version 22.0.

Results: A total of 184 CAD patients who underwent CABG surgery were included in the study and 114(62%) of them were males and 70(38%) were females. The age range was 25 to 40 years with the mean age of 36.5±3.17 years. The risk profile displayed that increased BMI was the major contributor for cardiovascular disease i.e. 38% patients were overweight, 10.9% were in Obese I category and 5.97% were in obese II category. Following obesity, hypertension (49.5%), diabetes (29.9%) and dysfunctional lipids (14.7%) were common comorbid conditions. While smoking and positive familial history also contributed to the risk ratio. It was observed that hypertension, diabetic history was more among overweight and obese individuals (p=0.029 & 0.666).

Conclusion: Young CAD patients ≤40 years of age display decreased risk and adverse outcomes as compared to the older counterparts but the clinical pattern of presentation is different and hence require different strategic attention.
HIPMI ORGANIZATION COMMUNICATION PATTERNS IN THE "HIPMI GOES TO SCHOOL" PROGRAM
Authors: Yanti Maria Fifi , Gusfa Henni
Published: May 2020

The Indonesian Young Entrepreneurs Association (HIPMI) is an organization focused on developing entrepreneurship among Indonesia's young generation. This study intends to determine the communication patterns of HIPMI in implementing HIPMI Goes to School. This study aims to identify the flow of messages, barriers in the communication patterns of HIPMI through the HIPMI Goes to School program to foster the spirit of Social Entrepreneur in Indonesia's young generation. This research uses a case study method with a paradigm of the constructivist approach. Data obtained through in-depth interviews, literature study, observation, and internet searching. The data analysis techniques are carried out, through several stages, namely data reduction, data collection, data presentation, drawing conclusions, and evaluations. The results of the HIPMI organizational communication pattern research in implementing the HIPMI Goes to School program is the Triangle Pipe pattern. The obstacles in the organization's communication patterns in the HIPMI Goes to School activities are more on the busyness and time distribution of members who have other duties besides organizational tasks. The role in organizational communication patterns in HIPMI Goes to School activities is carried out following their respective responsibilities, both those that act as opinion leaders, gatekeepers, bridges, cosmopolites, liaison, and isolates.
SIGNIFICANT RELATIONSHIP INTELLECTUAL CAPITAL AND MACRO ECONOMICS: A CASE STUDY
Authors: Subagyo Ahmad , Wulandari Siti Zulaikha , Saharuddin Desmadi
Published: May 2020

This paper aims to investigate the relationship between intellectual capital of several companies in Indonesia and macroeconomic variables Indonesia during the period 2011-2017 at 61 companies listed on the Stock Exchange. In this study using several intellectual capital variables in 61 companies and some Indonesian macro-economic variables are intellectual capital variable, Indonesian bank interest rate, consumer price index, producer price index, exchange rate index, inflation. This paper uses multiple regression data analysis techniques with OLS proposal model, linear difference and log analysis. From the results of studies that have been done can be explained that with the OLS regression model the relationship between several variable intellectual capital with some macroeconomic variables partially and simultaneously significant, as well as the difference. With log linear regression model analysis relationship between several variable intellectual capital with some macro economic variable simultaneously significant and partially between some variable intellectual capital significant and not significant partially with macro economic variable.
DEVELOPMENT OF TRAVELING EQUIPMENT FOR CONSTRUCTION AND MAINTENANCE OF RAILROAD TRACK BASED ON 14-TON CLASS EXCAVATOR
Authors: Kwon Jiwoon , Lee Myunggyu
Published: May 2020

The unique traveling mechanism was established and investigated by a coordinated modeling and experimental effort and both results are compared for validation of newly developed traveling equipment based on the conventional excavator system. The various hydraulic characteristics such as flow rate, pressure, revolutions per minute (RPM), and torque was confirmed by numerical and experimental technique with the appropriate test bench. After the above processes, the experimental and analytical results were successfully correlated. As a result, this new traveling equipment can contribute to save the outstanding monetary cost during railway construction and maintenance in that this equipment facilitates the accessibility of the conventional excavator into the work site composed of the railroad track.
COMPARISON OF JAVA PROGRAMMING TESTING TOOLS
Authors: Gautam Shikha
Published: May 2020

Various testing tools have been used to find defects and measure quality of software which have been developed in different languages. This paper provides the overview of various testing tools and analyzed Java programming testing tools because Java programming is very important due to its mature nature to develop software. Java testing tools are analyzed based on various quality attributes. Analysis shows that selection of testing tool depends on requirement.
Yavaş Sanat: Ad Reinhardt’ın Siyah Resimleri Üzerine Bir Değerlendirme
Authors: OKKALI İlkay Canan , KÜÇÜKOSMAN Adil
Published: May 2020

Ad Reinhardt, 1950 ve 1960’larda Amerikan sanat piyasasına hem yazıları hem de resimleri ile yön vermiş bir sanatçıdır. Reinhardt, 1960-66 yılları arasında hepsi aynı formatta olan siyah resimlerini Neo-Platonizm, Zen Budizmi gibi felsefelerle Doğu-Batı saf resim geleneği ile bağlantı kurarak çalışır. Reinhardt için Budizm, Hinduizm ve Hristiyan mistisizminin geleneksel metinleri, siyah resimlerinin giderek artan bir şekilde karmaşık ve anlaşılması zor yapısına zengin bir zemin sağlayan, entelektüel açıdan merak uyandıran kaynaklar olmuştur. Reinhardt’a Zen ve bazı mistik alanlarla ilgili büyüleyici gelen şey ise, bu alanların anlamsızlık ve boşluk kavramlarıyla ilişkili olması ve soyut sanatı farklı bir yolla anlatabilmek için sanatçının duyduğu ihtiyaca karşılık verebilmesidir. Bu çalışmanın amacı, Reinhardt’ın üretmiş olduğu siyah kare resimlerin biçimsel ve kavramsal temellerini ortaya koyarak 20. yüzyıl sanatındaki öznelliğini belirlemektir. Literatür taramasına dayalı hazırlanan çalışmada, sanatçının 1960-66 yılları arasında üretmiş olduğu hepsi aynı formatta olan siyah kare resimleri biçimsel ve kavramsal olarak incelenerek sanat anlayışı değerlendirilmiş, değerlendirme kendi söylemleri ve ilgili kaynaklarla desteklenmiştir. Veriler; yerli ve yabancı literatürden elde edilen basılı kaynaklara ek olarak çevrimiçi dergiler, kitaplar ve gazetelerden sağlanmıştır. Makalenin ilk bölümünde sanatçının erken dönem çalışmalarına değinilmiş ve siyah kare resimlerin oluşmasına zemin hazırlayan faktörler üzerinde durulmuştur. İkinci bölümde bu resimlerin yapım süreci ele alınarak teknik ve biçimsel olarak analiz edilmiştir. Son bölümde ise izleyicinin eserle karşılıklı diyaloğu ve resimlerin algılanışı ile yavaş sanat olarak değerlendirilmesinin sebepleri kavramsal açıdan ele alınmıştır. Elde edilen bulgulara göre; Reinhardt’ın 1960’lı yıllarda başladığı siyah formattaki resimlerinin algılanmasında felsefi ve yazınsal olarak etkilendiği Doğu sanatı ve meditasyonlarına benzer şekilde bir yavaşlığa ihtiyaç duyulduğu anlaşılmıştır. Yavaş sanat olarak adlandırılan bu kavramsal deneyimle izleyicinin algısında değişimler yaratmayı hedefleyen sanatçının eserlerinin anlık tüketime direnç gösterdiği tespit edilmiştir.
Geç Orta Çağ’da Fransisken ve Dominiken Mimarisi
Authors: ŞAHİN Duygu
Published: May 2020

Dilenci tarikatlar, Geç Orta Çağ İtalya ve Fransa’sında ticaret ve kentlerin canlanması, manastır cemaatlerinde reform ve kutsallık anlayışının değişmesi sonucu ortaya çıktı. Bu çalışmanın amacı Fransisken ve Dominikenler’in özgün mimari anlayışlarını ve bunun İtalyan komünleri ile Gotik mimari üzerindeki etkilerini incelemektir. Dilenci tarikatlar, Sistersiyan yönetmeliği ile Sistersiyan mimarisini benimsediler. Üst örtüsü ahşap kirişli nef sistemini çapraz tonozlu, düz biten koro yeri ile ana altarın yanında şapellerle tamamladılar. 13. yüzyılın sonundan itibaren diğer kiliseler de bu yapı tipini benimseyince dilenci tarikatlar Gotik mimarinin Batı’da homojen bir görünüm sunmasını sağladı. İtalya’daki tüccar ve bankerler mezar şapellerinin hamiliğini üstlendiklerinde komünün katedraline rakip kült mekanlar oluştu. Cemaat rahipleri tepki olarak kendi kiliselerinde de uygun gömü alanları yarattılar. Anıtsal dilenci kiliseleri, içinde bulundukları kentsel mekanı da dönüştürdü. Biraderler kiliselerin çevresindeki arazileri çeşitli ihtiyaçlarını gidermek için satın aldılar. Bu kiliselere açılan sokaklar genişletilip meydanlar inşa edildi. Fransisken ve Dominiken vaizler buralara kürsüler koyup vaaz vererek geleneksel Hristiyan ritüel mekanlarını değiştirdiler.
Karakterisasi Morfologi dan Pengaruh Perlakuan Pemupukan dan Pemberian Silika (Si) pada Genotipe Hibrida Anggrek Cattleya
Authors: Krishardianto Adimas , Sukma Dewi
Published: May 2020

Cattleya merupakan anggrek yang memiliki bunga dengan ukuran besar dan disebut queen of orchid  karena memiliki keindahan dari variasi warna pada bunganya. Pemupukan berperan penting dalam pertumbuhan dan perkembangan tanaman. Silika berperan dalam memperkuat jaringan tanaman sehingga lebih tahan serangan penyakit dan hama. Penelitian ini bertujuan untuk mengetahui pengaruh pemupukan dan pemberian silika (Si) terhadap pertumbuhan beberapa hibrida anggrek Cattleya. Penelitian dilakukan di rumah Anggrek  Departemen Agronomi dan Hortikultura, IPB pada bulan April hingga Juli 2015. Percobaan dilakukan menggunakan Rancangan Kelompok Lengkap Teracak (RKLT) dengan faktor tunggal yaitu perlakuan pemupukan. Terdapat empat perlakuan yaitu pupuk organik cair lengkap 2 ml L-1, NPK 32:10:10 2 g L-1, pupuk organik cair lengkap 2 ml L-1 + silika 2.5 ml L-1, dan NPK 32:10:10 2 g L-1 + silika 2.5 ml L-1. Perlakuan terdiri dari tiga kali ulangan, setiap ulangan terdiri dari 3 tanaman. Hasil karakterisasi menunjukan tidak terdapat keragamaan pada penampang melintang daun serta posisi pembungaan, bentuk ujung, susunan, bentuk tepi dan tekstur permukaan daun, tipe pembungaan, resupinasi, perhiasan, serta bentuk bunga. Pupuk yang memberikan hasil paling baik untuk ketiga genotipe adalah pupuk organik cair lengkap ditambahkan silika (Si) pada 5 parameter pengamatan yaitu pertambahan jumlah, panjang, lebar dan tebal daun, serta muncul anakan baru.
Stimulasi Pertumbuhan Stek Pucuk Torbangun (Plectranthus amboinicus Spreng.)
Authors: Karmila . , Suharsi Tatiek Kartika
Published: May 2020

Torbangun  (Plectranthus  amboinicus  Spreng.)  merupakan  tanaman  indigenous  yang  dimanfaatkan daunnya sebagai sayuran, obat, dan sumber zat gizi mikro. Sistem perbanyakan torbangun saat ini hanya dilakukan secara vegetatif yaitu dengan setek batang, namun metode perbanyakan dengan setek belum banyak dikembangkan. Tujuan penelitian ini yaitu untuk mempelajari peran stimulan yang efektif untuk pertumbuhan setek pucuk torbangun. Penelitian dilaksanakan di Kebun Percobaan Babakan Dramaga dan Laboratorium Pengujian Mutu dan Penyimpanan Benih Institut Pertanian Bogor pada bulan April  2015 sampai Juli 2015. Rancangan yang digunakan adalah rancangan acak kelompok satu faktor yang terdiri dari tujuh taraf perlakuan yaitu setek tanpa perlakuan stimulan, setek  + stimulan sintetik  100 ppm, setek+      stimulan sintetik 150 ppm, setek + stimulan alami urin sapi 15%, setek + stimulan alami urin sapi 25%, setek+ stimulan alami ekstrak bawang merah 40%, dan setek + stimulan alami ekstrak bawang merah 60%. Setiap perlakuan terdiri dari tiga ulangan. Setiap satuan percobaan terdiri dari delapan setek sehingga didapatkan 168 setek. Stimulan alami dan sintetik tidak efektif terhadap pertumbuhan setek pucuk torbangun.
Manajemen Panen Kelapa Sawit (Elaeis guineensis Jacq.) Berdasarkan Kriteria ISPO dan RSPO di Kebun Sei Batang Ulak, Kabupaten Kampar, Riau
Authors: Harahap Yuanda Pangi , Junaedi Ahmad
Published: May 2020

Kegiatan penelitian yang dilaksanakan di kebun Sei Batang Ulak (SBU), PT.Ciliandra Perkasa ini bertujuan untuk mempelajari aspek teknis dan manajerial dalam Pengelolaan perkebunan kelapa sawit, dan secara khusus mempelajari aspek pemanenan kelapa sawit. Aspek khusus pemanenan dipelajari dengan cara ikut melaksanakan kegiatan panen dan melaksanakan pengamatan pada beberapa komponen panen di kebun untuk mengetahui keefektifan dan keefisienan kegaitan panen di kebun SBU. Pengamatan yang dilakukan menunjukkan bahwa manajemen panen yang sudah ada cukup baik, akan tetapi perlu ditingkatkan agar didapatkan produksi tandan buah segar (TBS) yang optimal. Beberapa hal yang perlu dievaluasi meliputi tenaga kerja panen yang masih kurang, penggunaan alat pelindung diri yang masih minim, target panen yang belum terpenuhi, dan mutu buah yang kurang baik. Berdasarkan hasil pengamatan juga menunjukkan bahwa aspek  panen  belum  sesuai  dengan  prinsip  Indonesian  Sustainable  Palm  Oil (ISPO)  dan  Roundtable Sustainable Palm Oil (RSPO). Belum diterapkannya kriteria ISPO dan RSPO ditunjukkan dari kurangnya sosialisasi dan mewajibkan kepada tenaga kerja untuk menggunakan alat pelindung diri ketika bekerja, membawa anak-anak pada saat kerja di lapangan. Oleh karena itu, kebun SBU belum mendapat sertifikasi ISPO maupun RSPO.
Perlakuan Benih diantara Periode Penyimpanan untuk Meningkatkan Daya Simpan Benih Kedelai (Glycine max (L.) Merr.)
Authors: Kusumastuti Shinta Nugraheni , Widajati Eny
Published: May 2020

Tujuan penelitian ini adalah mendapatkan perlakuan benih diantara periode penyimpanan  untuk meningkatkan daya simpan benih kedelai. Penelitian dilaksanakan di Laboratorium Teknologi Benih, Departemen Agronomi dan Hortikultura, Fakutas Pertanian, Institut Pertanian Bogor pada bulan Desember 2013 hingga April 2014. Perlakuan benih  yaitu  (1) pencucian dengan air hangat , (2) pencucian dengan air dingin, (3) pencucian dengan fungisida mankozeb, (4) penjemuran di bawah matahari. Benih yang telah diberi perlakuan (1), (2) dan (3) dikeringkan hingga mencapai kadar air 8 - 9% dengan cara dijemur di bawah matahari. Benih   disimpan di ruang suhu rendah (± 5 °C) dan di ruang kamar (26-30 °C) menggunakan plastik polipropilen (0.08 mm). Hasil penelitian menunjukkan bahwa benih yang tidak diberi perlakuan hanya mampu mempertahankan daya berkecambah 80% hingga 6 minggu. Perlakuan pencucian benih dengan fungisida mankozeb, pencucian dengan air dingin dan penjemuran benih tanpa dicuci terlebih dahulu dapat meningkatkan viabilitas benih serta dapat mempertahankan daya berkecambah >80%  hingga akhir penyimpanan, 16 minggu setelah perlakuan baik pada penyimpanan suhu rendah maupun suhu kamar. Perlakuan penjemuran di bawah sinar matahari dapat menjadi pilihan terbaik sebagai perlakuan invigorasi benih diantara periode penyimpanan karena murah dan mudah dilakukan serta memberikan hasil yang baik.
Morbimortalidad en pacientes egresados de una unidad de cuidados intensivos en Boyacá, Colombia
Authors: Barragan Becerra Julian Andres , Moreno Mojica Claudia Maria , Hernández Bernal Nubia Esperanza
Published: May 2020

Objetivo: determinar la morbimortalidad de pacientes luego del alta en una UCI en Boyacá durante un periodo de 20 meses. Materiales y métodos: estudio descriptivo trasversal con análisis de información de registros, historias clínicas y datos derivados de la aplicación de una encuesta; la población fue de 592 pacientes egresados vivos entre los meses de enero de 2015 a agosto de 2016 de la UCI con base en los promedios mensuales de atención. Resultados: de los 592 pacientes atendidos se encuentra una sobrevida del 63,9% dentro del primer mes del alta y una mortalidad del 36.1%, la cual fue mayor dentro de los primeros diez días pos egreso. Del total de la población atendida, el 55,2% corresponde a pacientes de sexo masculino y el restante 44,8% pacientes femeninas. La edad promedio fue de 58,9 años. La morbilidad reportada obedece principalmente a enfermedades metabólicas entre el 24,5% y 26,5%, alteraciones cardiovasculares, 14,7% y 19,7%, infecciosas con un 14,3% y 11,1% y politraumatismos el 8,7%. Conclusiones: El porcentaje de personas que sobreviven tras recibir atención en UCI corresponde a un indicador de eficiencia en la atención del paciente en condición crítica de salud. Las patologías prevalentes en los individuos fueron de etiología metabólica como diabetes mellitus, insuficiencia renal crónica, infarto agudo de miocardio, septicemias, politraumatismos e infecciones. Los datos constituyen un elemento determinante para formular políticas y planes de atención e intervenir efectivamente a los pacientes en condición crítica de salud tanto a nivel regional como nacional.
Karakteristik Kimia dan Fisik Bubur Instan Berbahan Dasar Tepung Jagung Pulut dan Tepung Kacang Merah
Authors: Palijama Syane , Breemer Rachel , Topurmera Miranda
Published: May 2020

People tend to choose their food practically and efficiently presented and made without reducing their nutritional content. The use of red bean flour is needed to replace protein sources while waxy rice flour contributes to carbohydrate replacement. The purpose of this study was to know and to determine the characteristics of instant porridge with the ratio of red bean flour and waxy corn flour. Results showed that the characteristics of instant porridge were influenced by the different ratios between red bean and waxy corn flour on instant porridge ash, protein, fat, fiber, carbohydrate contents as well as ask bulk density and rehydration powder. The ratio between corn and red bean flours of 80% and 20% resulted in instant porridge with moisture, protein, and carbohydrate of 3.44%, 10.8%, and 80.53%, respectively and met the quality standard set by SNI 01-7111.4-2005, an ash content of 1%, a fat content of 0.76% the fiber content of 3.79%, bulk density of 1.03 g/mL, and rehydration power of 2.83 mL/g.: instant porridge, the ratio of red bean, and waxy flour.

Keywords: instant porridge, the ratio of red bean and waxy cornflour

 

ABSTRAK

Masyarakat lebih memilih makanan yang dikonsumsi secara praktis dalam bentuk penyajian maupun dalam pembuatannya tanpa mengurangi pemenuhan kebutuhan gizi. Penggunaan tepung kacang merah diperlukan sebagai sumber protein dan penggunaan tepung jagung pulut sebagai pengganti karbohidrat. Tujuan dari penelitian adalah untuk mengetahui dan menentukan karakteristik bubur instan dengan rasio tepung kacang merah dan tepung jagung pulut. Hasil penelitian menunjukan bahwa karakteristik bubur instan dipengaruhi oleh rasio tepung kacang merah dan tepung jagung pulut yang berbeda terhadap kadar air, kadar abu, kadar protein, kadar lemak, kadar serat, kadar karbohidrat, densitas kamba dan daya rehidrasi. Hasil penelitian menunjukkan rasio tepung jagung pulut 80% dan tepung kacang merah 20% memiliki karakteristik kadar air (3,44%), kadar protein (10,8%) dan kadar karbohidrat (80,53%) sesuai SNI 01-7111.4-2005, kadar abu (1%), kadar lemak (0,76%), kadar serat (3,79%), densitas kamba (1.03 g/mL) dan daya rehidrasi (2.83 mL/g).

Kata kunci: bubur instan, tepung jagung pulut dan tepung kacang merah
Apresentação
Authors: Cunha Teresa , Carvalho Claudia Cristina , Moreira Luciana
Published: May 2020

Apresentação do Dossiê
A fronteira interior da Palestina: uma análise do filme Maria’s Grotto para uma outra compreensão feminista da nação
Authors: Cunha Teresa
Published: May 2020

A fronteira interior é como uma alteridade que não se verga à narrativa nacionalista viril, violenta e totalitária. É a partir deste argumento que analiso Maria’s Grotto, um filme de 2007, da autoria da realizadora palestiniana Buthina Khoury sobre os crimes de honra na palestina de hoje. É uma obra onde três narrativas se conjugam e se repelem em vários momentos para que, nesse processo de aproximação e de exasperação mútua, o argumento se vá produzindo pelas imagens, vozes e silêncios do documentário. Ouço e vejo três narrativas que transcorrem pelo tempo e tomam forma através dos espaços e dos tempos onde as quatro estórias sobre aquelas quatro mulheres palestinianas são contadas. Neste ensaio procuro ouvir as vozes, mas também ver os rostos, os lugares e os gestos com que estas mulheres interrompem o insuportável ruído de fundo sobre as mulheres assassinadas na palestina por serem acusadas de desonrar as suas famílias. Não é meu objectivo principal teorizar sobre este filme mas, sim reflectir sobre ele e com ele, tendo como pano de fundo uma abordagem feminista pós-colonial.