bluuebunny/crossref_metadata_2025 huggingface dataset:
ISOLATION AND STRUCTURAL IDENTIFICATION OF TRITERPENE COMPOUNDS FROM THE LEAVES OF RUBUS ANNAMENSIS CARDOT COLLECTED IN LAM DONG PROVINCE
Authors: Le Thi Diem Trinh , Nguyen Le Hue Anh , Tran Thi Ngoc Bich , Nguyen Thi To Uyen , Huynh Thanh Truc , Trinh Thi Diep
Published: September 2024

From the leaves of Rubus annamensis Cardot collected in Lam Dong Province, two triterpene compounds were isolated and identified as niga-ichigoside F1 (2α,3β,19α,23-tetrahydroxy-urs-12-en-28-oic acid-β-D-glucopyranosyl ester) and ursolic acid (3-beta-3-hydroxy-urs-12-ene-28-oic acid) by using chromatographic and spectroscopic methods (IR, 1H-NMR, 13C-NMR, DEPT, HSQC, HMBC, and ESI-MS). This is the first time these compounds have been isolated from Rubus annamensis.
Isotope hydrology (2H and 18O) of Ikka fjord and its tufa columns, SW Greenland
Authors:   Overgaden neden Vandet 5A,1.tv., DK-1414,  Copenhagen K, Denmark, Buchardt Bjørn , Stockmann Gabrielle ,   Department of Earth Sciences, University of Iceland, Reykjavik,  Iceland, Hansen Marc O. ,   Danish Nature Agency, DK-4500,  Nykøbing Sjælland, Denmark, Sveinbjörnsdóttir Árný ,   Institute of Earth  Sciences, University of Iceland, Reykjavik, Iceland
Published: September 2024

From 1995 to 2022, several expeditions have visited the small Ikka fjord in SW Greenland to study growth and stability of the more than 1000 submarine tufa columns build of the metastable, cold-water carbonate ikaite (CaCO3·6H2O). The different water types in the area have been sampled for geochemical and stable isotope (2H and 18O) investigations. Here we present the results of more than 300 isotope analyses of water from the fjord and from streams, lakes, springs and tufa columns. Fjord water samples identify a two-component mixing system (R2 > 0.99) between freshwater runoff and sea water entering from the Davis Strait. The fresh water samples have an average composition of –95.4‰ δ2H and –13.1‰ δ18O. We f ind both seasonal and altitude effects in fresh water related to early (June–July) or late (August) sampling time. All freshwater samples excluding lakes but including previous precipitation data (GNIP, 1963–1974) can be described by a Local Meteoric Water Line with slope of 6.43 ± 0.12 and offsets between 6.34 and 6.56. Column water samples are mixed with fjord water but extrapolation to a chlorine-free composition defines an endmember composition of –102‰ δ2H and –14.2‰ δ18O. These composi tions identify precipitation on top of the igneous plateau at ~ 500 m altitude as the source for the column water.
Primera aproximación a los artefactos de molienda del sudeste del lago del Colhué Huapi (Chubut, Argentina)
Authors: Prieto María Eugenia , Ciampagna María Laura , Lamuedra Laura , Peralta González Santiago , Micozzi Elisa María , Hammond Heidi , Zilio Leandro , Aigo Juana del Carmen , Moreno Julián Eduardo
Published: September 2024

The Sarmiento Basin (Chubut, Argentina) has offered a privileged environment for the development of human life over the Holocene. For decades it was considered that the groups that inhabited this area based their economy on the hunting of terrestrial mammals, mainly Lama guanicoe. However, the new evidence suggests a diversification in the economy at particular times, adding new resources, technologies and/or ways of processing them. Within this framework, the goal of this work was to carry out a first characterization of grinding artifacts found at the southeast of the Colhué Huapi lake. For this purpose, distributional and spatial arrangement were analyzed, as well as dimensional, state of conservation and general techno-morphological variables. The results warn of a high number of active and passive artifacts made with local raw materials, whose diversity of shapes, weights, and states of conservation suggest a heavy equipment of space. Added to other technologies —such as ceramics and specific artifacts for fishing—, they would indicate an intensification in the use of resources towards the end of the late Holocene, suggesting as well an important place for grinding practices in the life of the hunter-gatherers who inhabited this area.
Los desechos de talla en Colmillo Sur I (NO de Santa Cruz, Patagonia Argentina)
Authors: Dekmak Wendy
Published: September 2024

Lithic resources serve as indicators of the diversity of activities conducted at a site, 
offering insights into the nature of its occupations. This study delves into the character of the Colmillo Sur I site (South-central Patagonia), which was persistently occupied during certain periods, from 7,424 to 535 cal AP. To do so, our investigation explored the informative potential of knapping debitage from a reduction sequence perspective. Our results provide deeper insights and expand upon previously identified trends at the site. We identified that activities involving different raw materials were generally similar but characterized by dissimilarities based on their quality and origin. Furthermore, these trends remained generally stable in most of its occupations. This suggested a consistent character throughout the site's occupational history.
Synthesis and conformational analysis of pyran inter-halide analogues of ᴅ-talose
Authors: Lessard Olivier , Grosset-Magagne Mathilde , Johnson Paul A , Giguère Denis
Published: September 2024

In this work, we describe the synthesis of halogenated pyran analogues of ᴅ-talose using a halo-divergent strategy from known 1,6-anhydro-2,3-dideoxy-2,3-difluoro-β-ᴅ-mannopyranose. In solution and in the solid-state, all analogues adopt standard 4C1-like conformations despite 1,3-diaxial repulsion between the F2 and the C4 halogen. Moreover, the solid-state conformational analysis of halogenated pyrans reveals deviation in the intra-annular torsion angles arising from repulsion between the axial fluorine at C2 and the axial halogen at C4, which increases with the size of the halogen at C4 (F < Cl < Br < I). Crystal packing arrangements of pyran inter-halides show hydrogen bond acceptor and nonbonding interactions for the halogen at C4. Finally, density functional theory (DFT) calculations corroborate the preference of talose analogues to adopt a 4C1-like conformation and a natural bonding orbital (NBO) analysis demonstrates the effects of hyperconjugation from C–F antibonding orbitals.
Pengembangan Modul Struktur Atom Berbasis Guided Discovery Learning (GDL) Terintegrasi TPACK untuk Fase E SMA
Authors: Ulfa Weni  , Yerimadesi Yerimadesi
Published: September 2024

Peserta didik kesulitan memahami materi struktur atom dan bahan ajar yang tersedia kurang inovatif dan belum memanfaatkan teknologi secara maksimal. Oleh karena itu, penelitian ini bertujuan mengembangkan modul struktur atom berbasis GDL terintegrasi TPACK untuk fase E SMA yang valid dan praktis. Model pengembangan Plomp yang dibatasi hingga diperoleh prototipe IV pada tahap small group. Uji validitas modul dilakukan oleh expert review yang terdiri dari tiga orang dosen kimia FMIPA UNP dan dua orang guru kimia SMA negeri di Padang. Uji praktikalitas dilakukan oleh dua orang guru kimia SMA negeri di Padang dan 15 orang peserta didik fase F SMA negeri di Padang. Instrumen yang digunakan berupa angket validitas dan praktikalitas, uji validitas dianalisis menggunakan formula Aikens’V dan uji praktikalitas menggunakan presentase skor capaian praktikalitas produk. Dari hasil analisis penelitian diperoleh nilai rata-rata Aikens’V sebesar 0,85 dengan kategori valid dan nilai praktikalitas oleh guru dan peserta didik sebesar 88% dan 89%. Hasil penilaian menunjukkan bahwa modul struktur atom berbasis terintegrasi TPACK untuk fase E sudah valid dan praktis, sehingga dapat dilanjutkan ke tahap berikutnya untuk uji efektivitas.
El Programa Articulado Nutricional y la desnutrición infantil en la región Huánuco, Perú
Authors: Amancio Adriana , Calero Roberto
Published: September 2024

Objetivo. Determinar la relación entre el Programa Articulado Nutricional (PAN) y la desnutrición crónica en niños menores de 5 años en la Micro Red de Salud de Panao, provincia de Pachitea, región Huánuco (Perú), para el período 2018-2021. Métodos. Fue un estudio de nivel correlacional y un diseño no experimental. Se usaron datos secundarios de la DIRESA-Huánuco y del portal web Consulta Amigable del Ministerio de Economía y Finanzas para estimar el coefciente de correlación de Pearson. Resultados. Se evidencia una relación negativa entre el PAN y la desnutrición crónica infantil en el distrito de Panao, con un valor del coefciente de correlación de Pearson de -0,74. Así mismo, se halló una relación negativa entre la desnutrición crónica infantil y las dimensiones del PAN: gestión de los bienes y servicios del PAN (-0,47), asignación presupuestal (-0,66) y ejecución presupuestal del PAN (-0,70). Conclusiones. Existe relación entre el PAN y la desnutrición crónica en niños menores de 5 años en la Micro Red de Salud de Panao Salud Panao, para el período 2018-2021
Mortalidad neonatal en parto culturalmente adecuado versus parto convencional en Hospital San Luis de Otavalo, Ecuador, 2017-2022
Authors: Pacheco Quintana Carmen , Pomasqui-Echeverría Marco Antonio
Published: September 2024

Objetivo. Determinar indicadores de mortalidad neonatal relacionados con el parto culturalmente adecuado versus parto convencional dentro del Hospital San Luis de Otavalo, en el periodo 2017-2022. Métodos. El estudio tuvo un enfoque cuantitativo de tipo observacional, retrospectivo, no experimental. la población estuvo constituida por total de neonatos registrados en el Hospital durante este periodo. Resultados. La mortalidad neonatal general según tipo de parto fue del 41,7 % de los casos presentándose en quirófano (asfixia y prematuridad) y domicilio (sepsis y prematuridad), seguido del 33,3 % como producto de la modalidad del parto culturalmente adecuado (asfixia, anencefalia y cardiopatía cianotizante), mientras que el 25 % ocurrió en condiciones de parto convencional (óbito fetal, SFA y prematuridad). Conclusiones. La tendencia de la mortalidad neonatal es decreciente, sin diferencias significativas entre ambas modalidades de parto. La totalidad de las pacientes encuestadas mostraron satisfacción por el tipo de parto culturalmente adecuado.
La Protección del Estado Boliviano respecto al Abandonado y Maltrato del Niño, Niña y Adolescente
Authors: Kevin Josue Colque Acapa , Lovera Oscar Mamani , Jhoanny Belen Titichoca Villegas , Fabiola Lisbeth Choque Mamani
Published: September 2024

El objetivo principal de este trabajo es identificar las causas del maltrato y abandono de niños y adolescentes en Bolivia, proponiendo políticas y programas para mejorar esta situación con apoyo estatal. Se busca investigar la implementación de programas de protección y sugerir mejoras que aborden tanto los efectos como las causas subyacentes del problema con una justificación que radica en la alarmante realidad que enfrentan estos menores, quienes a menudo son abandonados y reciben poca atención del Estado. Se resalta la necesidad de profesionalización en el sector y la asignación de recursos para mejorar la calidad de atención. Se consideró una metodología que incluye el método científico, inductivo y de observación, cada uno contribuyendo a obtener información objetiva y verificada sobre la problemática. Se obtuvo la multicausalidad del maltrato infantil, sugiriendo que es esencial enfocarse en las causas estructurales, como la violencia y la crisis económica, promover la participación de los niños en las decisiones que afectan su vida. Una asignación adecuada de recursos es vital para mejorar la efectividad de la atención en hogares dependientes del Estado.
The effect of the asymmetric arrangement of the horizontal shaft at different parameters of the formation anisotropy
Authors:   Korkyt Ata Kyzylorda University, Seitzhanov S.S. , Suleymanov N.S. ,   Korkyt Ata Kyzylorda University, Tanzharikov P.A. ,   Korkyt Ata Kyzylorda University, Kurbanov D.T. ,   Korkyt Ata Kyzylorda University
Published: September 2024

The article is devoted to the calculation of the productivity of a horizontal oil well for the development of oil or oil and gas fields is important. There is no doubt that for powerful formations, dense reservoirs, fractured deposits with vertical cracks, etc., the use of horizontal wells is becoming a necessity and has practically no alternative. But this provision is not a guarantee of obtaining an oil flow rate for a long time that significantly exceeds the flow rate of vertical wells. The stability of a horizontal well with a high flow rate requires the study of the influence of several factors on the performance of horizontal oil wells. In particular, these factors include: reservoir parameters (permeability, anisotropy, depression on the formation, etc.); the location of the horizontal trunk relative to the roof and sole of the skid-shaped formation and pressure loss in the horizontal trunk.
IMPACTO DA PRÁXIS E INTERVENÇÃO FARMACÊUTICA NA ADESÃO AO TRATAMENTO DE PACIENTES ONCOLÓGICOS: O ENGENDRAMENTO DAS ESTRATÉGIAS DE SEGURANÇA E EFICIÊNCIA FARMACOTERAPÊUTICA
Authors: Mendonça Valdirene Lima , Deuner Melissa Cardoso , Vieira Matheus Rodrigues , Cedro Leandro Pedrosa , Pinheiro Ana Gabriele Gonçalves , Nery Arminda Maria Barros , Santos Edson Rodrigues dos , Folha Jéssica dos Santos , Santos Alexandre Pereira dos , Oliveira Gregório Otto Bento de
Published: September 2024

No desafiador contexto do tratamento oncológico, o papel do farmacêutico é essencial para o sucesso do paciente. Vai além da simples dispensação de medicamentos, sendo um guia fundamental na complexidade do tratamento contra o câncer. Atuando como educador e especialista, esclarece dúvidas, instrui sobre o uso correto dos medicamentos e capacita o paciente para o autocuidado. Sua experiência em terapia medicamentosa garante a escolha personalizada de medicamentos, monitoramento rigoroso e contribui para a eficácia e segurança do tratamento. O farmacêutico também desempenha o papel de gestor de riscos, prevenindo interações medicamentosas e outros eventos adversos, proporcionando uma visão holística na equipe multiprofissional. Essa colaboração otimiza o tratamento e a qualidade de vida do paciente. Além disso, a atuação do farmacêutico contribui para uma melhor adesão à terapia, aumentando as chances de cura e reduzindo o tempo de internação. O alívio de sintomas melhora o sono, apetite e humor, proporcionando uma melhor qualidade de vida.
PERDA DE GRÃOS NA COLHEITA MECANIZADA DE MILHO (ZEA MAIZ, L.) EM FUNÇÃO DA VELOCIDADE OPERACIONAL
Authors: Faggion Francisco , Correia Tiago Pereira da Silva , Linhares Victória , Gomes da Cruz Haniel Carlos , Dias Malheiros Marcos , Nunes de Macedo Romério , Oliveira Silva Emilly
Published: September 2024

A velocidade de colheita da cultura do milho é importante para que a operação alcance bom rendimento e as perdas de grãos sejam reduzidas. O objetivo do trabalho foi avaliar as perdas de grãos na colheita mecanizada de milho em função da velocidade operacional. Para realizar o presente trabalho foram selecionadas cinco velocidades de deslocamento da máquina (4,0; 4,5; 5,0; 5,5 e 6,0 km h-1). O experimento foi realizado na Fazenda Querência, situada no município de Cristalina, GO. Foi utilizada uma colhedora de grãos automotriz da marca Case, modelo Axial-Flow 7230, ano 2016 equipada com plataforma de corte para colheita de milho modelo Bocuda 8170, da Vence Tudo de oito metros (16 linhas afastadas em 0,5 m). A área da lavoura foi dividida em parcelas, com delineamento inteiramente casualizado. Antes de iniciar a coleta das amostras foram realizadas amostragens em toda a área para determinar as perdas de grãos em pré colheita (perda natural), sem a interferência da máquina. Posteriormente foram coletadas as amostras das perdas de grãos na plataforma de corte e total (após sistema de trilha e limpeza) nos diferentes tratamentos. Para cada velocidade foram realizadas 4 repetições, totalizando 20 parcelas experimentais. As perdas na plataforma não variaram com a velocidade de colheita. As perdas nos mecanismos internos aumentaram para limites fora dos toleráveis após a velocidade de deslocamento ultrapassar 5,5 km h-1. A velocidade de 6,0 km h-1 ocasionou maiores perdas econômicas. De acordo com os resultados, para minimizar as perdas de grãos de milho durante o processo de colheita, é recomendado colher em velocidades de até 5,5 km h-1.
TEORIAS DO CURSO DE VIDA: INFLUÊNCIA DA HISTORICIDADE E EXPERIÊNCIAS NO COMPORTAMENTO ATIVO DAS PESSOAS
Authors: Souza Adriano , Silva Cristiane , Araújo Daniela , De Miranda Roberta , De Oliveira Marina , Conceição Ariani , Fonseca Rodrigo , Dos Santos Lucas , Dos Santos Clarice , Munaro Hector
Published: September 2024

Discutir, por meio das teorias do curso de vida, a relação da historicidade e das experiências no comportamento ativo das pessoas. Trata-se de uma revisão integrativa de literatura sobre as teorias do curso de vida relacionado a historicidade e das experiências do comportamento ativo das pessoas, realizado a partir de artigos relativos à temática. Com base nisso, os estudos foram ordenados e apresentados como resultado dessa pesquisa da seguinte forma: historicidade e experiências relacionadas ao comportamento ativo na infância e adolescência, na fase adulta e na velhice. Os conhecimentos acerca das teorias do curso de vida indicam que as experiências subjetivas possibilitam a compreensão das atitudes, bem como dos condicionantes necessários para o favorecimento da prática habitual de atividade física pelo indivíduo em cada fase de sua vida. Contudo, as discussões relacionadas ao assunto até o presente momento tematizam as principais diferenças históricas que influenciam no comportamento ativo das pessoas, informações estas que possibilitam o desenvolvimento de ações que estimulem o comportamento ativo das pessoas.
RESGATE E CONSERVAÇÃO IN VITRO DE ESPÉCIES FLORESTAIS NATIVAS AMEAÇADAS
Authors: Jesus Regivaldo da Silva , Oliveira L. S. , Silva Leonardo Máximo , Carvalho L. R.
Published: September 2024

As espécies florestais nativas representam um patrimônio genético de valor inestimável e garantem a sustentabilidade de ecossistemas naturais. Na região norte de Minas Gerais são encontradas espécies florestais pertencentes aos biomas Cerrado e Caatinga. Grande número delas está sob risco de extinção devido à exploração extrativista predatória por populações locais, e à ocupação danosa da agropecuária. Ademais, a carência de informações científicas, bem como a falta de tecnologias adequadas à propagação e programas de melhoramento florestal têm limitado a exploração do potencial econômico/silvicultural das mesmas. A diversificação da produção madeireira em detrimento da exploração dos remanescentes florestais nativos corresponde a uma opção para atender a demanda crescente do mercado e também ampliar a oferta de materiais genéticos. Dentre as espécies florestais que ocorrem naturalmente na região norte de Minas Gerais com aptidão para exploração madeireira, estão a aroeira do sertão (Astronium urundeuva Fr. All.), o cedro-cheiroso (Cedrela odorata L.), a braúna do sertão (Schinopsis brasiliensis Engl.), o gonçalo alves (Astronium fraxinifolium Schott.), o itapicuru (Goniorrhachis marginata Taub) e o pau d’alho (Gallesia integrifolia Spreng.). O cultivo destas espécies, além de possibilitar a conservação in situ de recursos genéticos, são opções sustentáveis para áreas desmatadas ou degradadas e alternativa de renda ao produtor. Dessa forma, a biotecnologia florestal, por meio da técnica de micropropagação oferece uma solução para a propagação e conservação destas espécies, possibilitando a multiplicação rápida e conservação de germoplasma e a manutenção da variabilidade genética, contribuindo para a preservação de espécies de valor econômico.
CONJUNTURA DOS ESTUDOS E PESQUISAS NO CAMPO DA PEDAGOGIA EMPRESARIAL: REVISITANDO A LITERATURA ACADÊMICA DA ÁREA
Authors: Barros Shisleyel de Carvalho , Sarmento Januário Neto Pereira , Carvalho Dhyorrana Soares Pereira , Pereira Daiane Aparecida Ribeiro Sarmento
Published: September 2024

O Pedagogo possui um amplo leque de áreas profissionais de atuação, incluindo ambientes escolares e não escolares. Dentre os ambientes não escolares pode-se mencionar a atuação dos pedagogos nas empresas, sendo este o foco do presente estudo. Portanto, o objetivo deste trabalho foi realizar o levantamento e a exploração da produção científica recentemente produzida no Brasil que aborda a pedagogia empresarial, enquanto campo de atuação dos profissionais da pedagogia. Foi realizada uma Revisão Sistemática da Literatura (RSL) com abordagem qualitativa. O recorte temporal da pesquisa foi cinco anos, de 2019 a 2024. Os resultados retornaram diversos subtemas no campo da pedagogia empresarial. Notou-se que a ênfase das pesquisas recai sobre dois subtemas principais: relatos de experiências de atuação do Pedagogo nas empresas e as funções distintas do pedagogo nesse meio. Dada a relevância do pedagogo inserido nesse campo de atuação, verificou-se que suas habilidades o tornam capaz de contribuir com a mitigação de problemas organizacionais e o coloca como agente de mudanças, contribuindo para os colaboradores atingirem as metas estabelecidas pelas empresas. Não obstante, sugere-se que mais pesquisas nessa temática sejam realizadas, visando aprofundar o conhecimento nesta área de estudo.
IMPACTO DAS CONDIÇÕES DE ARMAZENAMENTO NA QUALIDADE TECNOLÓGICA DO ÓLEO BRUTO DE ARROZ: UMA ABORDAGEM COM MACHINE LEARNING
Authors: ÁVILA B. P. , MACEDO L. D. , KREMER F. S. , GULARTE M.A.
Published: September 2024

Este estudo investigou o impacto das condições de armazenamento nos grãos de arroz, com ênfase na qualidade do óleo bruto extraído e no uso de técnicas de machine learning para analisar os dados. Os grãos foram armazenados por 12 meses em ambiente com alta umidade relativa e temperatura ambiente. Durante esse período, observou-se uma redução no teor de óleo e aumentos nos índices de peróxido e saponificação. Técnicas de machine learning foram aplicadas para identificar os parâmetros críticos que afetam a qualidade do óleo, permitindo prever mudanças na composição química ao longo do tempo. Os resultados demonstram que a integração de análises físico-químicas com machine learning pode otimizar o armazenamento, garantindo a manutenção da qualidade do óleo de arroz.
O USO DA ESTIMULAÇÃO MAGNÉTICA TRANSCRANIANA (EMT) NA FUNÇÃO MOTORA DO MEMBRO SUPERIOR PARÉTICO EM PACIENTES PÓS ACIDENTE VASCULAR CEREBRAL (AVC).
Authors: Candeias Barros joão vynicius
Published: September 2024

ResumoIntrodução: O Acidente Vascular Cerebral (AVC) é uma condição caracterizada pela interrupção do fluxo sanguíneo cerebral, seja por obstrução de um vaso sanguíneo (isquemia) ou por seu rompimento. A Estimulação elétrica magnética transcraniana (EMT) é um dos métodos recentes desenvolvidos com a proposta de induzir a plasticidade neural de uma forma não invasiva, principalmente na função motora de membro superior. Objetivo: O uso da Eletroestimulação magnética trascraniana na função motora do membro superior parético em pacientes pós AVC. Metodologia: Trata-se de uma revisão de literatura, realizada por meio de bancos de dados científicos nas línguas portuguesa e inglesa: Scielo e Pubmed/Medline entre os anos de 2016 e 2024. Resultados/Considerações finais: O Acidente vascular cerebral é uma condição clínica grave e de grande angústia para os pacientes o que traz consequências na sobrevida e qualidade de vida, contudo a EMT se mostrou eficaz para a melhora da função motora no membro superior parético na fase aguda e qualidade de vida.
MÉTODOS DE REFRIGERAÇÃO DE CARCAÇAS E SUA RELAÇÃO COM A MACIEZ DA CARNE
Authors: Campos Danilo Ferreira
Published: September 2024

A aplicação de baixas temperaturas visa retardar as atividades microbianas, assim como as reações químicas e enzimáticas que provocam alterações nos alimentos. O processo de refrigeração é crucial para determinar a maciez da carne, e a escolha do método de refrigeração pode variar conforme a espécie, a velocidade de produção do produto e o tempo de prateleira desejado. Na refrigeração de carnes, são empregados procedimentos convencionais, método rápido, resfriamento ultrarrápido, super-rápido e por aspersão. Após o abate, a temperatura interna das carcaças geralmente varia entre 30 °C e 39 °C. Este calor residual deve ser dissipado durante o processo inicial de resfriamento, a fim de reduzir a temperatura interna da carcaça a valores próximos de 0 °C. Para o resfriamento das carcaças, as câmaras frigoríficas devem ser mantidas entre -4 °C e 0 °C, enquanto a temperatura ambiente não deve exceder 3 °C. Além disso, pode ser empregado outros métodos com o objetivo de alcançar a maciez da carne desejada em menos tempo, acelerar a transformação muscular em carne, diminuir os custos de produção nos frigoríficos, reduzir as perdas por evaporação durante o resfriamento e mitigar os efeitos adversos, como o encurtamento das fibras quando utilizado procedimentos de refrigeração mais intensivos.
PERFIL CLÍNICO-EPIDEMIOLÓGICO DA HANSENÍASE ENTRE OS ESTADOS DA AMAZÔNIA ENTRE OS ANOS DE 2017 A 2022
Authors: Souza Lucas Sousa de
Published: September 2024

Esse artigo tem como objetivo analisar o perfil clínico-epidemiológico da hanseníase nos estados da Amazônia entre 2017 e 2022, destacando as características dos indivíduos diagnosticados, a distribuição dos casos por sexo, faixa etária, raça/cor, escolaridade e apresentação clínica, bem como as tendências de incidência e prevalência da doença. Utilizando um estudo ecológico e análise de dados epidemiológicos do SINAN, o artigo identifica um total de 21.421 novos casos, com pico de detecção em 2017 e 2018 e uma redução nos anos subsequentes. Os resultados revelam maior prevalência entre homens de 30 a 59 anos, predominantemente de raça parda e com ensino fundamental incompleto. A forma clínica mais comum foi a dimorfa, e o esquema terapêutico PQT/MB foi o mais utilizado. A conclusão enfatiza a necessidade de estratégias de controle mais eficazes, incluindo maior educação em saúde e melhorias nos serviços de atenção básica, especialmente considerando as limitações impostas pela pandemia de COVID-19 na notificação e tratamento dos casos.
Outcome of radiotherapy for metastatic neuroblastoma
Authors:   Department of Surgery, College of Medicine, University of Baghdad, Baghdad, Iraq, Abdulrahaman Noor Muhammed , AL Abidy Haydar Hamza ,   Department of Surgery, College of Medicine, University of Baghdad, Baghdad, Iraq
Published: September 2024

Background. Neuroblastoma (NB) is a prevalent solid extracranial tumor that primarily affects children. It is the third most common type of cancer in children, following leukemia and brain tumors. Aim. The study aimed to discuss the clinical outcomes after adjuvant radiotherapy to the primary site in case of metastatic NB after good response to chemotherapy. Methods. A retrospective clinical-dosimetric study of 25 patients metastatic NB treated with radiotherapy at Baghdad Radiotherapy and Nuclear Medicine Center, at Baghdad Medical City Complex, Baghdad, Iraq. Data collection begin from December 2023 and March 2024. Data were collected retrospectively with review of records. The following variables were studied: sex, age, date of diagnosis, site of primary tumor, site of metastasis, chemotherapy, surgery, RT, RT sites, doses of RT, fractions of RT, recurrence sites, date of relapse and survival outcome for each patient. Follow-up period include look up to metastasis, site of metastasis, recurrence, site of recurrence and survival rates. Results. In relation to sex, males (14, 56%) were more than females (11, 44%). The mean age of NB cases was 45.64±17.6 months. In NB, suprarenal masses were the most common site of primary in 21 (84%) of patients. The most common site of metastasis of NB was bone marrow in 12 (48). The multi sites of recurrence was the commonest presentation in 48%. The relapse-free survival (RFS) was 22.38 months. 5 out of 25 patients were alive whereas 20 (80%) of cases were dead. The median follow-up time was 6 years, and the OS of NB in this study after optimal treatment was 2.46 years (95%CI= 1.705-3.21) for survivors. The MS was 4.84 years. The OS was 6 yrs for those diagnosed at 2017, 2 yrs for those diagnosed at 2018, 1.5 yrs for those diagnosed at 2019, 1.75 yrs for those diagnosed at 2020, 3 yrs for those diagnosed at 2021 and 1.5 yrs for those diagnosed at 2022. There was a significant difference among doses (Log Rank (Mantel-Cox)= 11.425, p=0.044). Conclusions. This study is the first study in Iraq that examines the clinical results of radiotherapy on the primary site in cases of metastatic neuroblastoma following induction chemotherapy. The suprarenal masses of neuroblastoma are the most often occurring main site. The primary sites of metastases for neuroblastoma (NB) are the bone marrow and bones. Timely detection and proactive treatment of NB can improve overall results. Reoccurrence of skeletal issues and the infiltration of bone marrow are frequently observed. There were no significant differences observed in terms of relapse-free survival and overall survival based on factors such as sex, age, location of the main tumor, chemotherapy, radiation treatment, surgery, and radiation therapy dosages.
Analisis Pesan Dark jokes dalam Konten Bintang Emon Tentang Kasus Penyiraman Air Keras Novel Baswedan di Media Sosial Instagram
Authors: Mointi Moh. Fahriwan , Thomas Abdul Wahab , Tamu Yowan , Kurnia Moh. Mirza
Published: September 2024

Dark jokes refer to a style of comedy that often focuses on subjects considered taboo or sentistive by most people. In Indonesiaan’s entertainment industry, one stand up comedian known by frequently using this style is Bintang Emon. In every piece of content, he creates and publishes through his social media accounts, particularly Intagram, Bintang consistently incorporates dark jokes that entertaint his audience or spark controversy. An example of this is his content that garnered significant attention when he criticized the court’s decision regarding the Novel Baswedan acid attack case. This research aims to analyze messages behind the dark jokes in Bintang Emon’s Instagram content related to the acid attack on Novel Baswedan. The research employs a qualitative approach and analyzes that content using Andrik Porwasito’s four stages of message analisys. The results indicate that Bintang Emon aims to convery a critical message using humor, particularly through satire, wordplay, and absurd analogies In relation to the case.
Perancangan Media Kampanye Sosial mengenai Pencegahan Tindak Kekerasan Pengeroyokan Terhadap Supporter Sepak Bola
Authors: Rumambie Wira Pratama , Mursalim Muhammad Akram , Thomas Abdul Wahab
Published: September 2024

Indonesia merupakan salah satu negara dengan jumlah penduduk terbesar di dunia, sehingga permasalahan sosial di Indonesia tidak lepas dari aspek demografi. Selain itu, penduduk Indonesia dari banyak suku, adat istiadat serta budaya yang sangat berbeda. Karena perbedaan yang begitu beragam, permasalahan sosial tidak dapat dihindarkan. Fenomena ini memerlukan perhatian serius dan upaya efektif melalui media kampanye sosial contohnya Ricko, korban salah sasaran pengeroyokan oleh sesama bobotoh dalam laga Persib kontra Persija Jakarta di Stadion Gelora Bandung Lautan Api yang menjadi korban pengeroyokan. Penelitian ini bertujuan untuk merancang media kampanye sosial yang efektif dalam menyampaikan pesan mengenai bahaya dan dampak negatif dari tindakan kekerasan pengeroyokan. Penelitian ini dilakukan menggunakan pendekatan komunikasi visual yang mempertimbangkan strategi komunikasi AISAS (Attention, Interest, Search, Action, Share), Konsep Pesan, dan Strategi Kreatif. Melalui media kampanye ini, pesan yang dihadirkan dapat menghindari tindakan kekerasan dan memilih penyelesaian konflik secara damai. Maka dari itu media kampanye ini dirancang dengan baik sehingga menjadi alat yang efektif dalam mengurangi angka kekerasan pengeroyokan dan memilih jalan damai dalam penyelasaian masalah.
Pemanfaatan Limbah Kulit Singkong Sebagai Absorban Alami Untuk Mengurangi Kadar Besi (Fe) Pada Air Sumur
Authors: Nakoe Moh Rivai , Ahmad Zul Fikar , Arsad Nikmatisni
Published: September 2024

Air yang digunakan masyarakat sebagai air minum dan kebutuhan sehari-hari seperti mandi, cuci piring, mandi, dan lainnya sebagainya harus aman dan memenuhi berbagai syarat yang telah ditentukan. Ditemukan beberapa sumur di Desa Toto Selatan mengandung kadar zat besi (Fe). Tujuan pengabdian ini adalah untuk meningkatkan pemahaman tentang pemanfaatan serbuk kulit singkong dalam menurunkan kadar zat besi (Fe) pada air sumur. Mitra kegiatan ini  Pemerintah Desa Toto Selatan Kecamatan Kabila. Metode yang digunakan adalah ceramah dan praktek yang diberikan dalam bentuk sosialisasi dan pelatihan pembuatan serbuk kulit singkong. Hasil pengabdian masyarakat ini menunjukan serbuk kulit singkong efektif dalam menurunkan kadar zat besi (Fe) pada air, terjadi peningkatan kemampuan masyarakat untuk menggunakan bahan alami kulit singkong untuk menurunkan kadar zat besi (Fe) pada air sumurnya, masyarakat mendapat transfer pengetahuan yang dapat diaplikasikan secara langsung dengan alat dan bahan yang mudah didapat, dan Masyarakat dapat menjual serbuk kulit singkong untuk menambah penghasilan keluarga.
Navigating Effective Mentorship Strategies: Insights from Medical Faculty Community of Practice
Authors: Vakani Farhan Saeed , Ali Sana
Published: September 2024

Mentors often struggle to understand their mentees' needs and to determine effective support strategies that impact the mentor-mentee relationship. This is particularly common among medical faculty, who lack formal training and opportunities to discuss and share. In light of the current situation, we organized an open seminar titled “Empowering Medical Faculty as Mentors” on January 6, 2024, followed by a full-day workshop on February 3, 2024, at Dow University of Health Sciences. This research article aims to involve the medical faculty community of practice to discuss the challenges encountered and coming up with effective strategies in the realm of mentorship.
Methods
It was an exploratory case study. The event was attended by fifty-one faculty members from 18 medical and dental colleges in Karachi, Pakistan. They were selected based on their teaching experience, seniority, and age. The views and experiences of the participants were documented during discussions and validated through a thorough literature review. The collected data was analysed and coded into themes and subthemes, ultimately identifying strategies for effective mentor-mentee relationships.
Results
Twelve key strategies for effective mentor-mentee relationship were generated. They were identified as: socialised niceness; transformative capability; adapt a leadership style; psychological resources; manage high assumptions; self-assessment; build a positive connection; avoid pushing personal agenda; reward mentors; efficient time management; recognise gender as a social construct, and to build trust. These should be a valuable resource for new mentors and medical faculty members to be mindful of and consider while involved in the mentoring relationship.
Conclusion
Both mentor and mentee well-being have received more attention in recent years and is increasingly prioritized in higher education. The identified strategies establish a foundation for future research in health professions education and guidance for educators to be mindful of creating supportive professional relationships that benefit both mentor and mentee.
Madura dan Potensi Wisata Rempah: Kajian Strategi Komunikasi Pemasaran Pariwisata
Authors: Suryandari Nikmah , Rahmawati Farida Nurul , Adhidharma Ferry
Published: September 2024

PPandemi COVID-19 sempat  menghentikan aktivitas industri pariwisata global. Kondisi ini makin diperparah oleh suasana ketidakpastian dan kurangnya vaksinasi yang efektif. Hal ini berakibat orang mulai mencoba berbagai obat untuk meningkatkan kekebalan mereka,beralih ke praktik medis tradisional dan pengobatan alternatif. Penggunaan rempah dalam makanan maupun jamu dikenal sebagai salah satu potensi wisata Madura. Penelitian ini bertujuan mengetahui strategi komunikasi pemasaran pariwisata produk rempah Madura.   Tulisan ini menyajikan   ceruk sektor pariwisata yang menekankan  potensi wisata rempah.  Penelitian bertujuan mengetahui strategi komunikasi untuk mempromosikan  pariwisata  berbasis rempah dan untuk pengembangan wisata Madura. Penelitian menggunakan metode deskriptif kualitatif dengan informan para pelaku usaha wisata berbasis rempah di Madura. Hasil penelitian menunjukkan bahwa penggunaan strategi komunikasi pemasaran pariwisata di Madura menggunakan perspektif bauran pemasaran 7P yaitu dengan produk, harga, tempat, promosi, orang, proses, bukti fisik.
Strategi Komunikasi Politik “Nyantri” Prabowo Subianto dalam Memenangkan Pilpres 2024
Authors: Hafid Hafid , Jannah Siti Raudhatul , Jauhari Minan
Published: September 2024

Pemilihan umum 2024 melibatkan tiga kandidat pasangan calon presiden dan wakil presiden. Mereka bersaing ketat memperebutkan kursi nomor 1 di republik ini. Masing-masing menggunakan strategi politik terbaik demi memperoleh dukungan simpati rakyat. Termasuk salah satunya adalah Prabowo Subianto, calon presiden “bertahan” selama tiga periode pemilu berturut-turut belum juga muncul sebagai pemenang. Penelitian ini bertujuan untuk memahami strategi komunikasi politik Prabowo Subianto sebagai calon presiden untuk mendapatkan dukungan para santri dan kiai pesantren sebagai salah satu lumbung suara nasional. Penelitian ini menggunakan analisis framing Robert M. Entman dengan pendekatan pustaka yaitu media online sebagai objek penelitian yang dilaksanakan dalam kurun waktu sebelum masa kampanye hingga masa kampanye selesai. Hasil penelitian menunjukkan bahwa strategi komunikasi politik Prabowo dalam meraih dukungan kiai dan santri pondok pesantren adalah menggunakan tiga pola pencitraan. Pertama, Pure Publicity yaitu Prabowo mempopulerkan diri dengan sowan ke beberapa kiai pendukung pasangan Prabowo Gibran. Kedua, Free Ride Publicity yaitu Prabowo berkunjung ke pondok pesantren dan dinobatkan sebagai sahabat Santri Indonesia oleh para santri dan kiai. Ketiga, Paid Publicity yaitu Prabowo mengundang media untuk meliput dan menyiarkan acara deklarasi pasangan Prabowo Gibran sekaligus kampanye dana abadi pesantren.
Pengaruh Iklan Live Streaming Shopee terhadap Keputusan Pembelian Dimoderasi oleh Sikap
Authors: Elfera Syahedah Soeci , Sugiana Dadang , Bakti Iriana
Published: September 2024

Live streaming merupakan sebuah fenomena baru dan menjadi salah satu strategi pemasaran digital yang efektif untuk menarik perhatian konsumen dan mendorong keputusan pembelian. Artikel ini bertujuan untuk menganalisis pengaruh cognitive response pada iklan live streaming e-commerce terhadap keputusan pembelian. Penelitian dilakukan dengan menggunakan metode kuantitatif. Data dikumpulkan melalui survei kepada 96 responden yang pernah melakukan pembelian pada e-commerce Shopee dan menonton live streaming. Pengujian data menggunakan Path Analysis dengan teknik analisis Structural Equation Modeling (SEM) melalui pengolahan Partial Least Square (PLS). Hasil penelitian menunjukkan bahwa cognitive response pada iklan live streaming memiliki pengaruh positif terhadap keputusan pembelian melalui sikap sebagai variabel mediasi dengan nilai sebesar 0,564 atau 56%. Hal ini sejalan dengan asumsi dari teori cognitive response yaitu bagaimana konsumen memproses informasi dari iklan dan bagaimana respon kognitif ini mempengaruhi sikap dan keputusan pembelian mereka. Respon kognitif konsumen didapat  melalui pemikiran konsumen tentang produk, pemikiran konsumen pada sumber informasi dan pemikiran konsumen terhadap terpaan iklan. Faktor tersebut akan mengarah pada pembentukan sikap, baik sikap pada merek dan sikap pada iklan, dengan tahapan akhir adalah keputusan pembelian.  Temuan dalam artikel ini memberikan implikasi praktis bagi pelaku bisnis e-commerce agar fokus pada peningkatan kualitas konten dan interaksi antara pelaku bisnis ketika live streaming sedang berlangsung.
Improving prediction accuracy of open shop scheduling problems using hybrid artificial neural network and genetic algorithm
Authors: Komari Alaei Mohammad Reza , Rostamzadeh Reza , Albayrak Kadir , Turskis Zenonas , Šaparauskas Jonas
Published: September 2024

Scheduling issues are typically classified as constrained optimization problems that examine the allocation of machines and the sequence in which tasks are processed. Regarding the existence of one machine, identification of works processing sequence forms a complete time schedule. Therefore, following a review of previous works, the goal of the present study is designing a mathematical model for open shop scheduling (OSS) problems using different machines aiming at minimizing the maximum time required to complete the works using an artificial neural network (ANN) and genetic algorithm (GA). The research data were driven from a Shoe company carried out between the years 2019 and 2020. The GA and ANN methodologies were employed to analyze and forecast the scheduling of activities within the shoe manufacturing sector. The findings indicated that the probability associated with the third population of the GA was 0.15. Furthermore, an examination of the average values of standard error revealed that the neural network model outperformed in terms of predictive accuracy. The estimated minimum time necessary for task completion, as determined by the neural network, was calculated to be 0.96699, facilitating an optimal condition for meeting the established objectives.
Common for COVID-19 cytokine storm in patients with SARS-CoV-2 infection and CLL (chronic lymphocytic leukemia)
Authors: Kobakova Yozlem , Moneva-Sakelarieva Maria , Konstantinov Spiro , Momekov Georgi , Semerdzhieva Niya Emilova , Ivanova Stefka Аchkova , Atanasova Ventseslava Petrova , Atanasov Petar Yordanov , Vakrilova Becheva Maria Stamova
Published: September 2024

The cytokine storm has been identified as one of the leading causes of the severe course and, in some cases, the fatal outcome of COVID-19 infection. Other factors aggravating the course of the disease are accompanying disorders such as cardiovascular diseases, diabetes mellitus, diseases of the respiratory system, and oncological diseases. In this article, we present the course of the coronavirus infection in patients with an accompanying malignant disease, chronic lymphocytic leukemia (CLL), namely. The study included 8 patients with proven PCR-positive tests for SARS-CoV2 and confirmed chronic lymphocytic leukemia as a comorbidity. The course of the coronavirus infection in the CLL group was compared with that in the control group of 100 patients. In both groups, we compared subjective complaints such as tiredness, fatigue, and joint and muscle pain with objective criteria such as temperature, laboratory markers of inflammation, X-ray imaging, and frequency of necessary intubation.

Despite the expected poor prognosis in patients with concomitant oncological disease, in the case of chronic lymphocytic leukemia, our results showed a quite different milder coronavirus infection course. Obviously, patients with CLL cannot develop a pronounced cytokine storm, most probably due to certain immunosuppression related to the pathogenesis and drug treatment options for the comorbidity of CLL.
A new gorgonian Pseudopterogorgia nanjiensis sp. nov. (Cnidaria, Octocorallia, Gorgoniidae) from the Nanji Islands, China
Authors: Sun Tingzai , Xu Yu , Xu Kuidong , Chen Shun , Xie Shangwei , Zhan Zifeng
Published: September 2024

Members of the genus Pseudopterogorgia Kükenthal, 1919 are widely distributed in shallow water of the Indo-West Pacific. During an investigation of benthic biodiversity in the subtidal zone surrounding the Nanji Islands in the East China Sea, two specimens of Pseudopterogorgia were collected and described as a new species based on an integrated morphological-molecular approach. Pseudopterogorgia nanjiensissp. nov. is most similar to P. fredericki Williams & Vennam, 2001 in the irregular branching form and indistinct scaphoids, but differs by the coenenchymal sclerite content of distinct capstans and a few warty spindles and radiates (vs. mostly warty spindles and a few capstans), and a purplish colony (vs. white, pink to deep rose). Molecular phylogenetic analyses, based on the mtMutS-COI gene sequences, delineated a monophyletic clade encompassing all assessed Pseudopterogorgia species. Within this clade, P. nanjiensissp. nov. showed a close phylogenetic affinity with both P. fredericki and P. australiensis Ridley, 1884.
L’évaluation des coûts d’abattement des émissions en France
Authors: Criqui Patrick
Published: September 2024

L’évaluation des coûts d’abattement constitue une étape dans l’élaboration des stratégies de réduction des émissions économiquement efficaces. Dans le prolongement des travaux menés pour le calcul de Valeur de l’Action Climatique, France Stratégie a entrepris un ensemble de travaux portant d’une part sur la méthodologie de calcul des coûts d’abattement, d’autre part sur l’évaluation de ces coûts dans les grands secteurs d’activité. Ces études sectorielles permettent d’identifier les grandes options techniques de réduction des émissions, de calculer leur coût et d’identifier les horizons de temps auxquels elles deviennent coût-efficaces, par comparaison avec la Valeur de l’Action Climatique.
Hiver 2021 : délestage massif sur le réseau électrique texan – Leçons pour la France
Authors: Chavanne Xavier
Published: September 2024

Lors d’une vague de froid décennale en février 2021, des délestages massifs sur le réseau texan pour éviter son effondrement ont causé en quelques jours des centaines de morts et des pertes économiques de l’ordre de 5 % du PIB. Durant plus de 15 ans, les moyens de production pilotables, essentiels durant ces crises où la consommation atteint des records, ont été défavorisés au profit d’autres peu fiables par leur nature, les rendant moins disponibles. L’Europe a connu son dernier coup de froid similaire en février 2012. Depuis, le nombre et la rentabilité des générateurs fiables ont aussi été réduits. Cela pose la question de la capacité de notre système électrique en son état actuel à répondre à un tel événement météorologique.
Les Certificats d’Économie d’Énergie (CEE) : enseignements économiques généraux et comparaisons internationales
Authors: Gonand Frédéric
Published: September 2024

Les Certificats d’Économie d’Énergie (CEE) sont un instrument d’une politique d’efficacité énergétique. Ils ont des fondements théoriques économiques solides, bien analysés par la littérature académique du tournant des années 2010. Toutefois, leur mise en œuvre concrète s’avère complexe, et ces dispositifs conduisent à des économies d’énergie réalisées significativement plus faibles que celles estimées ex ante . Sur la base de la littérature académique disponible, cet article examine la question de l’efficacité économique des CEE tels qu’ils sont concrètement mis en œuvre dans les pays européens, et plus particulièrement en France, au Royaume-Uni et en Italie.
Pépinières d’entreprises un premier diagnostic
Authors: Albert Philippe
Published: September 2024

D’où vient le succès rencontré par les pépinières d’entreprises qui, en deux ans, ont su s’imposer tant en Europe qu’aux États-Unis comme des moyens propres à stimuler la création d’entreprises ? Philippe Albert a étudié attentivement le fonctionnement de ces nouveaux instruments, dans le cadre d’une enquête menée auprès de vingt-quatre pépinières implantées dans le monde entier. S’il est prématuré de tirer des conclusions générales sur les critères d’efficacité de ces réalisations encore très récentes, on peut néanmoins déjà repérer des conditions qui facilitent ou handicapent leur réussite.
La création d’entreprises high-tech
Authors: Mougenot Philippe , Albert Philippe
Published: September 2024

Les nouvelles entreprises de technologie avancée rencontrent les mêmes problèmes que toutes les jeunes sociétés, mais elles connaissent aussi des difficultés spécifiques tenant à leur origine, leur nature propre et leur environnement. Philippe Albert et Philippe Mougenot ont étudié les trois premières années d’activité de cent vingt-neuf entreprises innovantes. Ils analysent ici précisément les caractéristiques de ce nouveau style d’entreprises et montrent à quel point elles nécessitent, de la part de leurs dirigeants, un type de management adapté à leur univers.