bluuebunny/crossref_metadata_2025 huggingface dataset:
Influência do alongamento estático/passivo sobre o desempenho da força
Authors: Da Silva Nádia Lima
Published: December 2019

Atualmente observa-se uma restrição muito grande nas academias de musculação sobre a realização de alongamentos antes do treinamento de força (TF). Ainda não se sabe ao certo se o uso dessas atividades auxilia ou prejudica o executante em exercí­cios que exijam grande quantidade de força. O objetivo do estudo foi comparar a taxa do desempenho de homens treinados no exercí­cio de supino horizontal, submetidos í  realização de alongamento estático/passivo prévio ou não í  realização de séries consecutivas (3 séries) com carga máxima (10 RM). Participaram deste estudo 10 homens (27 ± 3,3 anos) com experiência mí­nima de um ano de TF. Utilizou-se estatí­stica descritiva para caracterizar os sujeitos e dados percentuais para determinar a queda do rendimento nas situações experimentais. Para determinar a diferença do rendimento utilizou-se o teste t de student para dados emparelhados, adotando-se uma significância de p â‰¤ 0,05. Verificou-se redução do desempenho da força muscular em ambas as situações experimentais, entretanto, essa perda foi maximizada na sessão que se utilizou de alongamentos precedendo o treinamento do supino reto (p < 0,05). Em valores percentuais, essa diminuição do desempenho foi estimada em 10,2% para a condição sem alongamento prévio e 27,4% para a condição com alongamento prévio entre a primeira e a última série.Palavras-chave: força muscular,Â flexibilidade,Â treinamento de resistência, desempenho atlético.Â
Treinamento muscular inspiratório para o desenvolvimento fí­sico: evidências e controvérsias
Authors: Soares Pedro Paulo da Silva
Published: December 2019

O Treinamento Muscular Inspiratório (TMI) visa o aumento da força e resistência dos músculos inspiratórios. Os efeitos positivos do TMI na melhora clí­nica e no desempenho fí­sico em indiví­duos com doença pulmonar obstrutiva ou insuficiência cardí­aca são bem reconhecidos, mas em indiví­duos sadios ainda são controversos. O objetivo do presente artigo é o de apresentar uma revisão sobre o possí­vel efeito positivo no desempenho fí­sico em indiví­duos sadios decorrentes do TMI. Observamos em todos os estudos consultados um aumento na força e resistência muscular inspiratória. Entretanto, nem todos os estudos apresentaram aumento na capacidade fí­sica, gerando controvérsia quanto í  aplicabilidade desta estratégia de treinamento objetivando desempenho. Verificou-se uma grande variação entre os protocolos descritos no que diz respeito í  carga utilizada, número de semanas, frequência semanal, além de formas de TMI, continua ou intervalada, em diferentes modalidades esportivas.Palavras-chave: treinamento muscular inspiratório, pressão inspiratória máxima, resistência muscular inspiratória, fadiga diafragmática.
Bases metabólicas da rabdomiólise e atrofia muscular
Authors: Manda Rodrigo Minoru , Burini Roberto Carlos
Published: December 2019

A redução da musculatura esquelética ou atrofia muscular ocorre gradativamente a partir dos 30 anos de idade, mas com significância importante a partir da 5ª década. Entretanto, ocorre em qualquer idade, na privação alimentar de carboidratos e no trauma. Pode ocorrer por denervação, desuso, deficiência nutricional, desequilí­brio hormonal e inflamação. A proteólise muscular ocorre predominantemente via ATP-ubiquitina-proteossoma e cooperativamente com os sistemas calpaí­na e caspase 3. Como promotores da proteólise figuram os glicocorticóides, o FOXO3 e as citocinas pró-inflamatórias. O TNFÎ±, ativa o NF-ÎºB tanto pelo Ca++ intracelular como pelas espécies reativas do oxigênio. Figuram como marcadores moleculares da atrofia muscular, a expressão aumentada dos genes MAFbx/atrogina 1 e MURF-1 e os marcadores proteolí­ticos como ubiquitina, calpaí­na, miostatina, TNFÎ± e NF-ÎºB. No geral, a rabdomiólise tem o estresse oxidativo como principal efetor e a disfunção mitocondrial, apoptose celular, como desfecho.Palavras-chave: rabdomiólise, proteólise, atrofia muscular, caquexia.
A influência de diferentes cadências e intensidades de exercí­cio sobre as respostas da frequência cardí­aca e da percepção subjetiva de esforço em ciclistas
Authors: Rossato Mateus
Published: December 2019

Em perí­odos de treinos e competições, os ciclistas utilizam cadências que não apresentam a maior economia de movimento, porém apresentam menor ativação neuromuscular. O objetivo deste estudo foi investigar as respostas cardiovasculares e psicológicas em diferentes cadências e intensidades de exercí­cio em ciclistas profissionais. Participaram oito ciclistas profissionais, os quais realizaram um teste incremental máximo e outros dois testes submáximos (60 e 80% da potência máxima), em que pedalaram na cadência preferida, 20% a menos da cadência preferida e 20% acima da preferida. Foi utilizada a ANOVA Two Way e o post-hoc de Tukey. Foi adotado p < 0,05. Pode-se concluir que a intensidade parece ser determinante na escolha das cadências preferidas, resultando na sua redução í  medida que intensidades maiores eram solicitadas, além disso, a elevação das cadências foi determinante para a elevação da demanda energética para ambas as intensidades. Adicionalmente, observou-se que as cadências preferidas pelos ciclistas não apresentaram os valores mais baixos de percepção subjetiva de esforço.Palavras-chave: ciclismo, frequência cardí­aca, cadência.
Intensidade auto selecionada, percepção subjetiva de esforço e tempo sob tensão no treinamento resistido em adolescentes
Authors: Tibana Ramires Alsamir
Published: December 2019

O objetivo deste estudo foi determinar a intensidade auto-selecionada, o tempo sob tensão e a percepção subjetiva de esforço no treinamento resistido em adolescentes sem experiência. Dezesseis adolescentes do sexo masculino (15,00 ± 0,97 anos; 59,23 ±10,37 kg; 1,70 ± 0,09; 12,23 ± 5,49 % de gordura; Tanner 4), realizaram duas semanas de familiarização no exercí­cio supino na máquina sentado, logo após realizaram o protocolo de intensidade auto selecionada, o teste de 10RM em ambos os protocolos foram medidos o tempo sob tensão e a percepção subjetiva de esforço. Os resultados demonstram que os valores da carga auto selecionada, do tempo sob tensão e da percepção subjetiva de esforço foram 56,44%, 38,36% e 51,16% significativamente inferiores aos valores obtidos durante o teste de 10RM. Portanto, adolescentes inexperientes não podem auto-selecionar uma intensidade suficiente para estimular uma melhora significativa na força muscular, e estão mais suscetí­veis a riscos decorrentes de repetições realizadas em alta velocidade com baixa resistência.Palavras-chave: intensidade auto-selecionada, adolescentes, treinamento de resistência.
Treinamento elí­ptico em hemiparéticos crônicos pós-AVC
Authors: Woellner Simone Suzuki
Published: December 2019

Introdução: O Acidente Vascular Cerebral (AVC) é uma das sí­ndromes mais incapacitantes da atualidade caracterizada por um déficit focal súbito de origem vascular. A incapacidade mais comum é a hemiparesia, e consequente déficit de marcha, equilí­brio e descondicionamento fí­sico. Estudos com diversas modalidades de treinamento vêm sendo publicados, e o treinamento elí­ptico pode ser inserido em programas de reabilitação neurológica. Objetivo: Avaliar os efeitos do treinamento elí­ptico em hemiparéticos crônicos pós-AVC. Materiais e métodos: Pesquisa quase experimental, tipo séries de tempo com três pré e pós-testes, com 4 indiví­duos hemiparéticos. Os instrumentos de medida utilizados foram esfigmomanômetro modificado para força do quadrí­ceps, teste de equilí­brio de Berg, Timed Up and Go e manovacuometria. O programa de treinamento teve frequência de duas vezes semanais durante 8 semanas (16 sessões). Resultados: Os sujeitos apresentaram uma melhora significativa pelo teste t (p < 0,05) nas medidas da velocidade da marcha e TUG, com melhora no desempenho de 35,2% e 22,07%, respectivamente, e pelo Berg, com melhora de 6,8%. Conclusão: O presente estudo buscou inserir uma nova modalidade terapêutica em um programa de reabilitação neurológica e os resultados iniciais devem incentivar novas pesquisas com diferenciação nos grupos de amostra. Palavras-chave: acidente vascular cerebral, hemiparesia, treinamento aeróbico.
Efektifitas Jamur Metharhizium anisopliae Menghambat Perkembangan Hama Uret pada Tanaman Cincau Hitam (Mesona palustris BL)
Authors: Andayanie Wuye Ria
Published: December 2019

Black grass jelly plants can be used as conservation plants. However, uret pests (Leucopholis rorida F.) are often complained that eat the base of the stems, flowers and roots at night. This study aims to determine: 1) the effect of M. anisopliae fungi on uret pests, (2) the level of susceptibility of uret pests, and (3) M. anisopliae fungal effectiveness on uret pests. This study used a completely randomized design (CRD) with 4 treatments and 5 replications. Data from the observations were analyzed using analysis of variance (ANOVA) with Duncan's Multiple Range Test (DMRT) 5% test carried out when diversity analysis showed a real effect. Uret mortality monitoring will be carried out after the application of fungi. by observing each uret and calculating the amount of uret mortality and average plant growth. The highest percentage of second instar larvae from uret was found in treatment P4 (manure and fungi were incubated for 72 hours at the next temperature of 28 oC applied to the field with straw mulch) which was 82, 98% at 12 days after application of fungi. The average growth of plants consisting of: root length, root volume, stem diameter and number of shoots was also found in treatment P4 (manure and fungi were incubated for 72 hours at the next 28 oC, applied to the field with straw mulch), respectively amounting to 12.45; 5.70; 1.88; 12,15. Dead larvae emit fluids such as ethanol and their bodies are weak, then the body dries and hardens and stiffens, like mummies and fungi forming green sporulation. Keywords—: black grass jelly plants; Leucopholis rorida F;Metharhizium anisopliae; mortality;effectiveness
Strategi Pengembangan Budidaya Jamur Tiram Di Kabupaten Magetan
Authors: Nareswari Widita , Talkah Abu , Daroini Ahsin
Published: December 2019

Magetan Regency which is located in the western end of East Java Province geographically has the potential in agriculture in the development of horticultural commodities namely oyster mushrooms. Oyster mushroom cultivation in Magetan Regency is relatively new with supporting factors such as affordable raw materials; cultivation techniques that are easy to learn; and humidity factors that support but have weaknesses, one of which is capital; farmer's motivation and tenacity; and the absence of technology application. Based on these conditions, this study aims to: (1) Identify and analyze internal and external factors that influence the development of oyster mushroom agribusiness in Magetan Regency (2) Formulate alternatives and recommend priorities for the development of oyster mushroom in the Regency Magetan. This research uses SWOT analysis and Process Hierarchy Analysis (AHP). The results showed the influential factors that obtained the highest score factors were organic crops, limited capital, motivation and persistence of farmers, public awareness of healthy food, weather and pests. Whereas the alternative that has the highest three priority values is to increase the number of baglogs along with the quality of the baglog quality of mushroom seeds, the application of appropriate management and human resources, and expand the reach of market share and the use of technology in marketing.
Dichrooscytus fervens sp. n., a new species of Miridae (Hemiptera, Heteroptera) from Finland
Authors: Muinonen Arto , Rinne Veikko , Vesterinen Eero
Published: December 2019

Dichrooscytus fervens Muinonen & Rinne sp. n. (Hemiptera: Heteroptera: Miridae) is described based on material collected in Finland between 2011 and 2018. A morphological description is provided along with DNA barcodes (COI gene) and a phylogeny of all the Dichrooscytus species for which a DNA barcode is available. The new species lives on Picea spp. and is still known only from Finland. A map of all the records is given, as well as an identification key of the Dichrooscytus species occurring in northern Europe.
The Investigation of Turbulent Buoyancy-Affected Flows for Cooling Applications
Authors: Etaig Saleh Ali , Elsharif Nabil
Published: December 2019

This paper details the Turbulent Flows that Affected with Buoyancy and the calculating of the heat transfer relevant to nuclear reactor in vertical pipe, the main topic when buoyancy effects play a significant role. Implementation of the analytical wall functions is used in when the aim is to reduce the computational cost, since conventional wall functions based on prescribed velocity and temperature profiles failed to predict heat transfer accurately in other than a simple shear at high Reynolds numbers. Thus, this work mainly concerns studying the effect of the buoyancy on heat transfer and turbulent flow applying the analytical wall function since it is based on the analytical solution of simplified Reynolds equations and using a new scaling function, which is used to modify the cell averaged dissipation rate. The approach gives results close to those obtained using AWF with scaling function introduced by Gerasimov. The benefit of using the Analytical wall function is that computational cost are more accurate than conventional wall functions. Many improvements added to the approach during its development have been employed in the present work. It has been successfully applied in natural, mixed and mixed convection flows for four different flow geometries.
ANALISIS KERUANGAN TINGKAT KESIAPSIAGAAN MASYARAKAT TERHADAP BENCANA BANJIR BERBASIS GIS DI KABUPATEN BOJONEGORO
Authors: Sa’ida Ita Aristia , Ma’ady Mochamad Nizar Palefi
Published: December 2019

Masyarakat yang hidup di daerah zona rawan banjir memiliki kesiapsiagaan tersendiri yang berbeda-beda tiap wilayah. Biasanya hal itu dipengaruhi oleh kesadaran masyarakat terhadap risiko dan pengalaman akan bencana banjir (Sutton dan Tierney,2006). Mengingat pada tahun 2007, Bojonegoro pernah dilanda bencana banjir besar yang setidaknya menenggelamkan 80% wilayah Kabupaten Bojonegoro (AntaraNews, 2007). Sehingga sasaran yang ingin dituju adalah untuk mengetahui tingkat kesiapsiagaan masyarakat dalam menghadapi berbagai fase bencana banjir dan analisis keruangan berbasis GIS. Tulisan ini menggunakan metode analisis statistik deskriptif dan analisis keruangan berbasis GIS. Studi ini difokuskan pada kesiapsiagaan yang ada di enam kecamatan terdampak banjir di Kabupaten Bojonegoro. Indikator-indikator yang akan digunakan untuk mengidentifikasi tingkat kesiapsiagaan adalah yang umumnya digunakan di beberapa kajian terdahulu yaitu (1) pengetahuan dan  sikap, (2) rencana tanggap darurat, (3) sistem peringatan dini, (4) mobilisasi sumber daya, dan  (5)  modal sosial (Sutton dan Tierney,2006). Dari hasil Pemetaan Tingkat Kesiapsiagaan Masyarakat terhadap berbagai fase bencana Banjir di Kabupaten Bojonegoro maka dapat diketahui bahwa rata-rata Tingkat kesiapsiagaan berada pada level sedang-tinggi, hal ini dibuktikan oleh perolehan analisis kuantitatif dari hasil wawancara yakni rata-rata berada pada angka 3-4. Sehingga penelitian ini penting dilakukan guna mengetahui tingkat kesiapsiagaan masyarakat terhadap berbagai fase bencana banjir di Kabupaten Bojonegoro.
RESEARCH OF FORMATION PROCESS OF SUBMICRON ELEMENTS OF OPTOELECTRONIC DEVICES CONSIDERING INFORMATION PROTECTION REQUIREMENTS
Authors: Ilchenko Anatoly , Karmanov Igor
Published: December 2019

In this paper, the term «hardware tab» is reviewed, critical stages of chip production on which tabs can occur are indicated, the possible consequences of tab activation are described. Also a method is described that does not allow the appearance of tabs, as an example of import substitution. The developed technological mode of submicron elements obtaining is shown, by the example of a polysilicon layer.
PROSPECTS FOR THE USE OF LIQUID LENSES OF PHOTO-VIDEO TECHNOLOGY OF UNMANNED AERIAL VEHICLES
Authors: Voytov Alexey , Mikhailov Igor
Published: December 2019

The article considers the relevance of the use of liquid lenses in variable lenses for photo-video equipment unmanned aerial vehicles. The above mentioned factors that reduce the operational performance of existing variable lenses with mechanical systems control the angular field of the optical system. The prospects of using liquid lenses as an alternative to mechanical systems of changing the angular field of the lens are named. The possibility of development of a monoblock of a zoom lens having movable elements with improved mass-dimensional and thermal pressure characteristics.
EXPERIENCE IN THE USE OF THE CONCEPT OF LEAN PRODUCTION INSTRUMENT-MAKING ENTERPRISE
Authors: Patsan Alexandr , Shaburova Aelita
Published: December 2019

The article considers the main features of lean manufacturing, technological marketing and how they are related. Increase of added value, decrease of cost and increase of competitiveness of the enterprise by means of introduction of technological marketing in production on the basis of lean production is shown.
Improve the Growth and Yield of Figs by Foliar Nutrition at Post-Harvest
Authors: Jameel Shamkhi Khalid , Abed Al-Kadhim Kamal Jawad , Salih Jabbar Luma
Published: December 2019

A factorial experiment was carried out by spraying the fig (Ficus carica L.) trees cv. Aswad  Diyala at post-harvest in the 2014 and 2015 seasons, in one orchards of Diwaniyah city/ Iraq, with two liquid fertilizers: Azomin and Prosol at 3 levels (0, 3 and 6) g.l-1 and (0, 2 and 4) g.l-1, respectively. The results showed that third level of both fertilizers gave The widest leaf area:{(5.53, 6.42) and (5.52 , 6.38)}m2.tree-1, highest leaf content of chlorophyll{(131.63 ,132.55), (132.63 , 130.93)}mg.100g-1more N percent of leaf {(2.12 , 2.11) ,(2.31, 2.34)}%, highest carbohydrates percent of leaf {(14.65 , 15.10) , (14.83, 15.02)}%, for compounds and seasons, respectively. As for the crop that took place in the 2015 and 2016 seasons gave the highest yield{(20.50, 21.66) (20.80, 21.30)}kg.tree-1, most level of K in the fruit{(280.10, 272.70), (292.40, 288.10)}mg.100g-1 and highest content of anthocyanin{(512.10, 519.90), (482.90, 494.50)} mg.100g-1. There was a significant interaction between the experimental factors, which reached a peak in the third level, in the leaf area in the 2014 and 2015 seasons (5.85 and 6.86) m2.tree-1, and the anthocyanin in the 2015 and 2016 seasons in fruit (518.20 and 534.80) mg.100g-1, respectively.

It can be concluded that the post-harvest spraying of Aswad Diyala cv., with the, Azomin and Prosol at the levels of 6 and 4g.l-1, respectively, gave the best results
Examining Chemotherapy-Related Cognitive Changes in Colorectal Cancer Patients: A Feasibility Trial
Authors: Dwek Marie-Rose , Rixon Lorna , Simon Alice , Hurt Catherine , Newman Stanton
Published: December 2019

Introduction: Research suggests that chemotherapy may be related to decline in patients cognitive functions.
Objectives: To assess the feasibility and acceptability of a multi-site study designed to examine the nature and extent of chemotherapy-related cognitive changes in colorectal cancer patients.
Method: Data was collected over 8 months using objective and self-reported measures of cognitive functioning and self-reported quality of life, fatigue and mood questionnaires. The assessment battery was administered pre- and mid-chemotherapy treatment to a consecutive sample of colorectal cancer patients across three Londonbased NHS Trusts. Participants included patients who had undergone colorectal surgery and were scheduled to have adjuvant chemotherapy treatment, or no further cancer treatment.
Main outcome measures: Recruitment procedures, rate of recruitment, suitability of exclusion/inclusion criteria, acceptability of data collection procedures and the battery, and attrition rates.
Results: From 1 April 2014 to 1 December 2014, 42 eligible participants were invited to take part in the trial. Of the 17 that completed pre-chemotherapy assessments, only 1 withdrew at follow-up due to reasons of ill health from disease recurrence. All participants completed the entire battery and indicated that they found the trial acceptable.
Conclusions: What went wrong: Strained researcher resources; loss of eligible participants to competing studies, restrictive upper age limit.
Possible solutions: Removal of upper age limit, an increased dedicated research team to increase rate of recruitment. The large multi-site study is feasible with suggested amendments and is acceptable to patients and medical teams. Acceptability of trial to medical teams is further evidenced by requests of collaboration from two additional London based NHS Trusts.
Lessons learned: This feasibility trial provides evidence to other researchers designing similar studies in this area of an acceptable design and the need for appropriate funding for resources to recruit large enough consecutive samples of patients with solid tumour cancers.
Frozen Section Assessment of Bronchial Margins during Lung Carcinoma Surgeries: Report of the Experience at a Single Institution
Authors: Hussein Siba El , Williams Roy , Alexis John
Published: December 2019

Introduction Many thoracic surgeons consider frozen section analysis of bronchial margins during lobectomies “obligatory” although routine frozen section analysis of the bronchial margin rarely yields positive results and infrequently changes intra-operative management in patients undergoing Non-Small Cell Lung Carcinoma (NSCLC) resection. Materials and methods 234 cases of lobectomies with carcinoma were reviewed at our institution to assess bronchial margin involvement, correlation between frozen section and final bronchial margin status, gross distance between tumor and margin, and tumor type. Results Tumor distance to margin varied in the 234 cases from grossly involved to 10 cm away. 5 cases out of 234 (approximately 2.1%) had a positive bronchial margin in the final report. 3 out of the 5 cases were poorly differentiated squamous cell carcinoma grossly abutting the bronchial margin, two cases were of poorly differentiated adenocarcinoma located grossly 0.5 cm away from the bronchial margin. 4 out of 5 cases were called positive intra-operatively. In none of the 4 out of the 5 positive cases did frozen section exam of the bronchial margins change the intra-operative management of the case. Conclusion Our study supports selective use of intra-operative frozen section of bronchial margins during lobectomies for carcinoma. On the basis of our findings, a distance of approximately 1 cm or less is suggested as a threshold for intra-operative microscopic examination of the bronchial margins. However, routine examination of the bronchial margins, regardless of the location of the tumor upon gross examination, and in the absence of empirical evidence supporting this practice, is only time consuming intra-operatively, wasteful of resources and has no therapeutic or prognostic value.
Micronuclei (MN), an Important Cancer Biomarker
Authors: Adhikari Aniket
Published: December 2019

Micronuclei (MN) formation has been observed (cancer and pre-cancerous lesions) of the oral cavity among betel quid chewers. Micronuclei act as a cancer biomarker which is related with smokeless tobacco associated genetic mutations. Micronuclei are a sensitive indicator of genetic damage. These are small, extra nuclear bodies that are formed during mitosis from lagging chromosomes. The test is used as a tool for genotoxicity and easily detectable without affecting the cancer patients. The present review focuses on the various types of cancer of the human body with micronuclei study.
Model Keperawatan Keluarga Santun Lansia dalam Upaya Peningkatan Kualitas Asuhan Keluarga pada Lansia: A Literature Review
Authors: Rekawati Etty , Hamid Achir Yani S. , Sahar Junaiti , Widyatuti Widyatuti , Sari Ni Luh Putu Dian Yunita
Published: December 2019

Family is the closest person to the elder person who has an important role in caring for elder person. The purpose of this study is to provide an overview of the cordial older family nursing model in an effort to improve the quality of family care in elder person. The study approach was the study of literature with expert agreement. The search method for library resources was done online, which uses databases such as Science Direct, Scopus, Sage, Pubmed and ProQuest. The keywords used were "elder mistreatemnt", "intervention" and "family approach". Literature search was only limited in 2008 to 2019 and in English. The results obtained 15 research articles analyzed. There were three themes obtained, namely the provision of information through training, giving positive perceptions to families who care for the elderly and counseling. Training was oriented towards family coping and coping strategies in caring for the elder person aimed at caregivers, cadres and health workers. Planting suggestions were given in groups or individually to families who care for the elderly, and counseling is given individually to families who need it. Further research is expected to be able to identify the quality of life of the elder person related to the application of the cordial older family nursing model.

Keywords: elderly; the cordial older family nursing model; family care quality

ABSTRAK

Keluarga merupakan orang terdekat lansia yang memilki peran penting dalam merawat lansia. Tujuan dari penulisan ini adalah memberikan gambaran model keperawatan keluarga santun lansia dalam upaya peningkatan kulitas asuhan keluarga pada lansia. Pendekatan studi adalah studi literatur dengan kesepakatan pakar. Metode pencarian sumber pustaka dilakukan online yaitu menggunakan basis data seperti Science Direct, Scopus, Sage, Pubmed dan ProQuest. Kata kunci yang digunakan adalah “elder mistreatment”, “intervention” dan “family approach”. Penelusuran literatur hanya dibatasi dalam tahun 2008 hingga 2019 dan dalam bahasa Inggris. Hasil yang didapatkan adalah didapatkan 15 artikel penelitian yang dianalisis. Ada tiga tema yang didapatkan, yaitu pemberian informasi melalui pelatihan, pemberian persepsi positif pada keluarga yang merawat lansia dan konseling. Pelatihan berorientasi pada dukungan dan strategi koping keluarga dalam merawat lansia yang ditujukan kepada pelaku rawat, kader dan petugas kesehatan. Penanaman sugesti diberikan secara berkelompok ataupun individual pada keluarga yang merawat lansia, dan konseling diberikan secara individual bagi keluarga yang memerlukannya. penelitian lanjutan diharapkan dapat mengidentifikasi mengenai kualitas hidup lansia yang berkaitan dengan penerapan model keperawatan santun lansia.

Kata kunci: lansia; model keperawatan keluarga; kualitas asuhan keluarga
Nausea-Vomiting and Anorexia in Post-Chemotherapy Patients
Authors: Gustini Gustini , Sukartini Tintin , Krisnana Ilya
Published: December 2019

Introduction: Some studies show that post-chemotherapy cancer patients experience nausea vomiting and anorexia, in RSUP Dr. Wahidin Sudirohusodo also found difficulties with nausea vomiting and anorexia. Aims: To the study was to prevent vomiting of nausea and anorexia in cancer patients after chemotherapy. Methods: 60 post-chemotherapy cancer patients who experienced nausea vomiting and anorexia were included in a crosssectional study. The selected subject fulfills the criteria. Study inclusion: Patients diagnosed with cancer in the Lontara 2 Chemotherapy Room. Patients who have received chemotherapy, adjuvant chemotherapy and additional chemotherapy, are ≥ 21 years old. Nausea and vomiting were measured using the INVR questionnaire and anorexia using a history of anorexia questionnaire. Data were analyzed using descriptive analysis. Results: based on the characteristics of respondents nausea and anorexia vomiting distributed 41-50 years, female sex, secondary school education, working as a housewife, cycles 1-4 times. Conclusion: Cancer patients after chemotherapy experience vomiting of nausea and anorexia. Nausea vomiting is caused by the effects of chemotherapy drugs which stimulate the digestive system, causing moderate and severe nausea and anorexia.

Keywords: nausea; vomiting; anorexia; cancer; chemotherapy

ABSTRAK

Pendahuluan: Beberapa studi menunjukkan pasien kanker pasaca kemoterapi mengalami mual muntah dan anoreksia, di RSUP Dr. wahidin Sudirohusodo juga ditemukan mengalami mual muntah dan anoreksia. Tujuan: untuk mengidentifikasi mual muntah dan anoreksia pada pasien kanker pasca kemoterapi. Metode: 60 pasien kanker pasca kemoterapi yang mengalami mual muntah dan anoreksia dilibatkan dalam penelitian crosssectional. Mual muntah dinilai menggunakan kuesioner INVR dan anoreksia menggunakan kuesioner riwayat anoreksia. Data dianalisis dengan menggunakan analisis deskriptif. Hasil: berdasarkan karakteristik responden yang mengalami mual muntah dan anoreksia mayoritas berusia 41-50 tahun, berjenis kelamin perempuan, berpendidikan sekolah menengah atas, bekerja sebagai IRT, siklus kemoterapi 1-4 kali. Kesimpulan: Mayoritas pasien kanker pasca kemoterapi mengalami mual muntah dan anoreksia. Mual muntah ini terjadi karena efek obat kemoterapi dapat meransang sistem gastrointestinal yang menyebabkan terjadinya mual muntah sedang dan berat serta mengalami anoreksia.

Kata kunci: mual; muntah; anoreksia; kanker; kemoterapi
An Exploratory Study of Types of Innovation in US Foundations
Authors: Jaskyte Bahr Kristina
Published: December 2019

While foundations contribute in significant ways to the United States’ social, economic, and political life, they are experiencing increasing demands placed upon them by their own sector and need to respond to the major changes in their external environment. In order to create breakthrough solutions to long-standing problems, foundations have to become more innovative and seek to experiment and find new approaches. Unfortunately, innovation discourse within foundations has received little attention. This paper fills the gap in the literature as it describes the results of a study that explored different types of innovations implemented in foundations. More specifically, staff members of 17 US foundations that are known for supporting innovation in nonprofit organizations, were asked to describe programmatic and administrative innovations implemented in their own foundations. The results showed that foundations that support innovation are in fact innovative themselves. They implemented numerous innovations in programmatic and administrative, financial, and structural areas. This paper provides a rich description of a broad range of innovations implemented within each of those areas. The contribution of this study and insights are significant at this particular time when foundations’ roles and impact on social change are questioned. The results can enrich our discussion of where foundations can go from here in terms of becoming innovative themselves in order to be able to support and enhance innovation in the nonprofit sector.
Paraoxonase 3: Structure and Its Role in Pathophysiology of Coronary Artery Disease
Authors: Priyanka Kumari , Singh Surjit , Gill Kirandip
Published: December 2019

Spanning three decades in research, Paraoxonases (PON1) carried potential of dealing with neurotoxicity of organophosphates entering the circulation and preventing cholinergic crisis. In the past few years, the Paraoxonase multigene family (PON1, PON2, PON3) has been shown to play an important role in pathogenesis of cardiovascular disorders including coronary artery disease (CAD). The PON genes are clustered in tandem on the long arm of human chromosome 7 (q21, 22). All of them have been shown to act as antioxidants. Of them, PON3 is the least studied member as its exact physiological substrate is still not clear. This has further led to limitation in our understanding of its role in pathogenesis of CAD and development of the potential therapeutic agents which might modulate its activity, expression in circulation and tissues. In the present review, we discuss the structure and activity of human PON3 enzyme and its Single nucleotide variants that could potentially lead to new clinical strategies in prevention and treatment of CAD.
Attachment and Adulthood in a Sample of Southeastern Mexico
Authors: Pérez-Aranda Gabriela Isabel , Peralta-López Vianey , Estrada-Carmona Sinuhé , García Reyes Liliana , Tuz-Sierra Miguel Angel
Published: December 2019

The main purpose of this research is to analyze the attachment styles of men and women from 20 to 40 years old (early adulthood) and from 40 to 65 years old (middle adulthood) who are in a romantic relationship and live in the City of San Francisco Campeche. A sample of 50 men and 50 women in early adulthood and 50 men and 50 women in middle adulthood was selected, and the questionnaire “Styles of Attachment” was applied. For the data analysis, we used the SPSS version 23 program along with student’s “t” and X2 (Chi2) tests. The results show no significant differences in attachment styles between male and female relationships. However, with respect to the stages analyzed, significant differences are found in attachment styles. In addition, there are significant differences with respect to the type of relationship: single people have secure attachment while married people display anxious attachment. We conclude that in early adulthood, secure attachment predominates, while in middle adulthood anxious attachment predominates.
The Entropy-Based Time Domain Feature Extraction for Online Concept Drift Detection
Authors: Ding Fengqian , Luo Chao
Published: December 2019

Most of time series deriving from complex systems in real life is non-stationary, where the data distribution would be influenced by various internal/external factors such that the contexts are persistently changing. Therefore, the concept drift detection of time series has practical significance. In this paper, a novel method called online entropy-based time domain feature extraction (ETFE) for concept drift detection is proposed. Firstly, the empirical mode decomposition based on extrema symmetric extension is used to decompose time series, where features in various time scales can be adaptively extracted. Meanwhile, the end point effect caused by traditional empirical mode decomposition can be avoided. Secondly, by using the entropy calculation, the time-domain features are coarse-grained to quantify the structure and complexity of the time series, among which six kinds of entropy are used for discussion. Finally, a statistical process control method based on generalized likelihood ratio is used to monitor the change of the entropy, which can effectively track the mean and amplitude of the time series. Therefore, the early alarm of concept drift can be given. Synthetic data sets and neonatal electroencephalogram (EEG) recordings with seizures annotations data sets are used to validate the effectiveness and accuracy of the proposed method.
Fault Ride-Through Characteristics of Small Wind Turbines
Authors: Kondoh Junji , Mizuno Hidetoshi , Funamoto Takuji
Published: December 2019

There is significant potential for an increase in the use of kilowatt-class small wind turbines (SWTs) in Japan due to reduced limitations with respect to installation, despite their high cost. At this stage, the Japanese grid code has not been considered sufficiently with respect to grid-connected SWTs, and the addition of fault ride-through (FRT) requirements for SWTs has been requested. Moreover, the FRT of SWTs is challenging to achieve owing to the low inertia constants when compared with those of large-scale wind turbines, which result in significant acceleration of the rotor speed and an increase in the input voltage of the power conditioning system (PCS) during FRT operation. In this study, FRT field tests were conducted on SWT systems against a voltage dip with a duration of ~ 1 s, and it was confirmed that the SWT systems satisfied the FRT requirements for photovoltaic (PV) systems connected to low-voltage distribution lines in Japan. The behaviors of the rotational speed of the SWTs and the PCS input voltage in an FRT operation were then analyzed, and it was noted that the increase in the PCS input voltage with the overspeed of the turbine can reach the upper limit and make the PCS cease operation, which indicates failure of the FRT. The overvoltage, therefore, requires restriction using a method such as pitch control, furling, and electrical and/or mechanical brakes.
Analysis of the Nexus of CO2 Emissions, Economic Growth, Land under Cereal Crops and Agriculture Value-Added in Pakistan Using an ARDL Approach
Authors: Ali Sajjad , Ying Liu , Shah Tariq , Tariq Azam , Ali Chandio Abbas , Ali Ihsan
Published: December 2019

The present study attempts to explore the correlation between carbon dioxide emissions (CO2 e), gross domestic product (GDP), land under cereal crops (LCC) and agriculture value-added (AVA) in Pakistan. The study exploits time-series data from 1961 to 2014 and further applies descriptive statistical analysis, unit root test, Johansen co-integration test, autoregressive distributed lag (ARDL) model and pairwise Granger causality test. The study employes augmented Dickey–Fuller (ADF) and Phillips–Perron (PP) tests to check the stationarity of the variables. The results of the analysis reveal that there is both short- and long-run association between agricultural production, economic growth and carbon dioxide emissions in the country. The long-run results estimate that there is a positive and insignificant association between carbon dioxide emissions, land under cereal crops, and agriculture value-added. The results of the short-run analysis point out that there is a negative and statistically insignificant association between carbon dioxide emissions and gross domestic product. It is very important for the Government of Pakistan’s policymakers to build up agricultural policies, strategies and planning in order to reduce carbon dioxide emissions. Consequently, the country should promote environmentally friendly agricultural practices in order to strengthen its efforts to achieve sustainable agriculture.
3D Dynamic Simulation of Heat Conduction through a Building Corner Using a BEM Model in the Frequency Domain
Authors: Simões Nuno , Prata Joana , Tadeu António
Published: December 2019

This paper sets out a three-dimensional (3D) boundary element method (BEM) formulation in the frequency domain to simulate heat transfer through a point thermal bridge (PTB) at a corner in a building envelope. The main purpose was to quantify the dynamic effect of a geometrical PTB in terms of distribution of temperatures and heat fluxes, which is useful for evaluating moisture condensation risk. The numerical model is first validated experimentally using a hot box to measure the dynamic heat behavior of a 3D timber building corner. The proposed model is then used to study the dynamic thermal bridging effect in the vicinity of a 3D concrete corner. Given the importance of the risk of condensation, this study looks at the influence of an insulating material and its position on the temperature and heat flux distribution through the PTB under steady state and dynamic conditions.
Writing Belonging: An Antillean Conversation Between Luisa Capetillo and Ofelia Rodríguez Acosta
Authors: Rivera Berruz Stephanie
Published: December 2019

This essay comparatively reads the intellectual contributions of Luisa Capetillo and Ofelia Rodríguez Acosta. I argue that Capetillo and Rodríguez Acosta offer unique and under-appreciated perspectives on what I term the assemblages of belonging that resist the regulatory normalization of sexuality and the reduction of the maternal body as the source of home and place making in the context of Puerto Rico and Cuba respectively. As the paper demonstrates, what it means to belong, in the context of Antillean women writers, is not entirely tied to a particular place or the identity of people. Rather, belonging is assembled through tactics that are always already decentered given the status of womanhood and its interpellations in the Caribbean at the turn of the 20th century, which was performatively accomplished through the acts of writing and reading. I argue that Capetillo and Rodríguez Acosta assemble notions of belonging through performative mechanisms that place them at the cross-roads between the affective, embodied, and relational dimensions of what it means to belong in a place that is not and continues not to be for any(body). Thus, they both betray the idea of being on one side or another.
Evaluation of the Major Steps in the Conventional Protocol for the Alkaline Comet Assay
Authors: Karbaschi Mahsa , Ji Yunhee , Abdulwahed Abdulhadi Mohammed S. , Alohaly Alhanoof , Bedoya Juan F. , Burke Shanna L. , Boulos Thomas M. , Tempest Helen G. , Cooke Marcus S.
Published: December 2019

Single cell gel electrophoresis, also known as the comet assay, has become a widespread DNA damage assessment tool due to its sensitivity, adaptability, low cost, ease of use, and reliability. Despite these benefits, this assay has shortcomings, such as long assay running time, the manipulation of multiple slides, individually, through numerous process steps, the challenge of working in a darkened environment, and reportedly considerable inter- and intra-laboratory variation. All researchers typically perform the comet assay based upon a common core approach; however, it appears that some steps in this core have little proven basis, and may exist, partly, out of convenience, or dogma. The aim of this study was to critically re-evaluate key steps in the comet assay, using our laboratory’s protocol as a model, firstly to understand the scientific basis for why certain steps in the protocol are performed in a particular manner, and secondly to simplify the assay, and decrease the cost and run time. Here, the shelf life of the lysis and neutralization buffers, the effect of temperature and incubation period during the lysis step, the necessity for drying the slides between the electrophoresis and staining step, and the need to perform the sample workup and electrophoresis steps under subdued light were all evaluated.
First Insights into the Effect of Low-Dose X-Ray Irradiation in Adipose-Derived Stem Cells
Authors: Schröder Annemarie , Kriesen Stephan , Hildebrandt Guido , Manda Katrin
Published: December 2019

(1) Background: Emerging interest of physicians to use adipose-derived stem cells (ADSCs) for regenerative therapies and the fact that low-dose irradiation (LD-IR ≤ 0.1 Gy) has been reported to enhance the proliferation of several human normal and bone-marrow stem cells, but not that of tumor cells, lead to the idea of improving stem cell therapies via low-dose radiation. Therefore, the aim of this study was to investigate unwanted side effects, as well as proliferation-stimulating mechanisms of LD-IR on ADSCs. (2) Methods: To avoid donor specific effects, ADSCs isolated from mamma reductions of 10 donors were pooled and used for the radiobiological analysis. The clonogenic survival assay was used to classify the long-term effects of low-dose radiation in ADSCs. Afterwards, cytotoxicity and genotoxicity, as well as the effect of irradiation on proliferation of ADSCs were investigated. (3) Results: LD (≤ 0.1 Gy) of ionizing radiation promoted the proliferation and survival of ADSCs. Within this dose range neither geno- nor cytotoxic effects were detectable. In contrast, greater doses within the dose range of >0.1–2.0 Gy induced residual double-strand breaks and reduced the long-term survival, as well as the proliferation rate of ADSCs. (4) Conclusions: Our data suggest that ADSCs are resistant to LD-IR. Furthermore, LD-IR could be a possible mediator to improve approaches of stem cells in the field of regenerative medicine.
TASK-3 Gene Knockdown Dampens Invasion and Migration and Promotes Apoptosis in KATO III and MKN-45 Human Gastric Adenocarcinoma Cell Lines
Authors: Cikutović-Molina Rocio , Herrada Andres A. , González Wendy , Brown Nelson , Zúñiga Leandro
Published: December 2019

Incidence and mortality of gastric cancer is increasing worldwide, in part, because of the lack of new therapeutic targets to treat this disease. Different types of ion channels participate in the hallmarks of cancer. In this context, ion channels are known to exert control over the cell cycle, mechanisms that support survival, angiogenesis, migration, and cell invasion. In particular, TASK-3 (KCNK9), a member of the K2P potassium channel family, has attracted much interest because of its oncogenic properties. However, despite multiple lines of evidence linking TASK-3 to tumorigenesis in various types of cancer, its relationship with gastric cancer has not been fully examined. Therefore, we set out to assess the effect of TASK-3 gene knockdown on KATO III and MKN-45 human gastric adenocarcinoma cell lines by using a short hairpin RNA (shRNA)-mediated knockdown. Our results demonstrate that knocking down TASK-3 reduces cell proliferation and viability because of an increase in apoptosis without an apparent effect on cell cycle checkpoints. In addition, cell migration and invasion are reduced after knocking down TASK-3 in these cell lines. The present study highlights TASK-3 as a key protein involved in migration and cell survival in gastric cancer and corroborates its potential as a therapeutic target for gastric cancer treatment.
Anti-Inflammatory and Antioxidant Properties of Dehydrated Potato-Derived Bioactive Compounds in Intestinal Cells
Authors: Basilicata Manuela Giovanna , Pepe Giacomo , Rapa Shara Francesca , Merciai Fabrizio , Ostacolo Carmine , Manfra Michele , Di Sarno Veronica , Autore Giuseppina , De Vita Daniela , Marzocco Stefania , Campiglia Pietro
Published: December 2019

Inflammation and oxidative stress are always more recognized as responsible for chronic disease at the intestinal level. Currently, a growing interest is addressed to the discovery of diet-derived products which have anti-inflammatory and antioxidant properties. This work aims to characterize the pharmacological potential of dehydrated potatoes. For this purpose, a simulated gastrointestinal digestion was carried out. The bioaccessible peptides were fractionated on the basis of their molecular weight and tested on intestinal epithelial cells (IEC-6) under oxidative and inflammatory conditions. Our results demonstrate that the tested peptide fractions were able to significantly inhibit tumor necrosis factor-α release and cycloxygenase-2 and inducible nitric oxide synthase expression. The tested peptides also showed significant antioxidant activity, being able to both reduce reactive oxygen species (ROS) release, also from mitochondria, and nitrotyrosine formation, and increase the antioxidant response by heme oxygenase-1 and superoxide dismutase expression. Moreover, the peptide fractions were able to significantly increase the wound repair in IEC-6. The obtained results indicate the anti-inflammatory and antioxidant potential of dehydrated potatoes at the intestinal level.