bluuebunny/crossref_metadata_2025 huggingface dataset:
Tools Aimed at Improving the Quality of Information Support of Management in Conditions of Digitalization
Authors: Zhurov Yu. V.
Published: April 2022

The article analyzes the term ‘digitalization’, identifies its specific features implying that this term, in spite of transformations due to complexity of tasks being resolved, does not lose its initial meaning. On the contrary, it was supplemented by new features that do not contradict to the primary definition but make it more topical in view of current objectives. On the basis of obtained results the term ‘information support of management’ was specified. At the present stage of society development the notion of information for providing optimal managerial decision should be understood as the information received by processing such volumes of data, which cannot be processed directly by person. The author shows the use of artificial neuron networks to provide the information support of management. The article substantiates that in order to improve the quality of management in the current conditions it is possible to use tools meant for analyzing big data. It is underlined that we can use data from different sources, internal and external ones. Reliability of these findings was demonstrated by processing the vacancy sample at enterprises of steel-making industry. The author confirmed an opportunity to improve the quality of information support of management through getting new information by using visualization of structured data.
Coupling of Thiols and Aryl Halides Mediated by Dicyclohexano-18- crown-6 and Potassium Carbonate
Authors: Deng Ning , Xu Hua-Jian , Liu Zhong-Lin , Xu Jing-Xiu , Dong Zheng , Shen Xiao , Xu Jun
Published: April 2022

Aims:

A simple, transition-metal-free C-S coupling protocol for the synthesis of aryl thioethers is reported.

Background:

Sulfur-containing moieties are ubiquitous in pharmaceutical drugs and materials and therefore methods for their construction are of great importance. One approach entails the catalytic coupling of an aryl halohydrocarbon with a thiol, but the transition metal catalysts usu-ally used are prone to poisoning by participating sulfur species and efficient catalysis is usually only achieved after complex ligand optimization.

Objective:

New transition-metal-free approaches to the synthesis of C-S bonds are urgently need.

Method:

We screened the reaction conditions such as alkali, crown ether, solvent, temperature, etc., tested the compatibility of the reaction substrate, and analyzed the mechanism process.

Result:

The optimized reaction conditions were determined to be 1.0 equiv of aryl halides and 1.2 equiv of thiols at 110 ℃ in toluene with K2CO3 (1.5 equiv) as a base, promoted by 10 mol% dicyclohexano-18-crown-6. Up to 33 examples of thioethers were synthesized under transition-metal-free conditions in good to excellent yields.

Conclusion:

We have developed a simple and efficient method for the C-S cross-coupling of a wide variety of (hetero)aryl halides and thiols mediated by dicyclohexano-18-crown-6 and with-out the need for transition-metal catalyst. In addition, the preparation and gram-scale experi-ments of a variety of drug molecules further verify the practicability of our developed method.
A Privacy-Preserving Audit and Feedback System for the Antibiotic Prescribing of General Practitioners: Survey Study
Authors: Yigzaw Kassaye Yitbarek , Chomutare Taridzo , Wynn Rolf , Berntsen Gro Karine Rosvold , Bellika Johan Gustav
Published: April 2022

Background

Antibiotic resistance is a worldwide public health problem that is accelerated by the misuse and overuse of antibiotics. Studies have shown that audits and feedback enable clinicians to compare their personal clinical performance with that of their peers and are effective in reducing the inappropriate prescribing of antibiotics. However, privacy concerns make audits and feedback hard to implement in clinical settings. To solve this problem, we developed a privacy-preserving audit and feedback (A&F) system.

Objective

This study aims to evaluate a privacy-preserving A&F system in clinical settings.

Methods

A privacy-preserving A&F system was deployed at three primary care practices in Norway to generate feedback for 20 general practitioners (GPs) on their prescribing of antibiotics for selected respiratory tract infections. The GPs were asked to participate in a survey shortly after using the system.

Results

A total of 14 GPs responded to the questionnaire, representing a 70% (14/20) response rate. The participants were generally satisfied with the usefulness of the feedback and the comparisons with peers, as well as the protection of privacy. The majority of the GPs (9/14, 64%) valued the protection of their own privacy as well as that of their patients.

Conclusions

The system overcomes important privacy and scaling challenges that are commonly associated with the secondary use of electronic health record data and has the potential to improve antibiotic prescribing behavior; however, further study is required to assess its actual effect.
Japanese Version of the Mobile App Rating Scale (MARS): Development and Validation (Preprint)
Authors: Yamamoto Kazumichi , Ito Masami , Sakata Masatsugu , Koizumi Shiho , Hashisako Mizuho , Sato Masaaki , Stoyanov Stoyan R , Furukawa Toshi A
Published: April 2022

BACKGROUND

The number of mobile health (mHealth) apps continues to rise each year. Widespread use of the Mobile App Rating Scale (MARS) has allowed objective and multidimensional evaluation of the quality of these apps. However, no Japanese version of MARS has been made available to date.

OBJECTIVE

The purposes of this study were (1) to develop a Japanese version of MARS and (2) to assess the translated version’s reliability and validity in evaluating mHealth apps.

METHODS

To develop the Japanese version of MARS, cross-cultural adaptation was used using a universalist approach. A total of 50 mental health apps were evaluated by 2 independent raters. Internal consistency and interrater reliability were then calculated. Convergent and divergent validity were assessed using multitrait scaling analysis and concurrent validity.

RESULTS

After cross-cultural adaptation, all 23 items from the original MARS were included in the Japanese version. Following translation, back-translation, and review by the author of the original MARS, a Japanese version of MARS was finalized. Internal consistency was acceptable by all subscales of objective and subjective quality (Cronbach α=.78-.89). Interrater reliability was deemed acceptable, with the intraclass correlation coefficient (ICC) ranging from 0.61 to 0.79 for all subscales, except for “functionality,” which had an ICC of 0.40. Convergent/divergent validity and concurrent validity were also considered acceptable. The rate of missing responses was high in several items in the “information” subscale.

CONCLUSIONS

A Japanese version of MARS was developed and shown to be reliable and valid to a degree that was comparable to the original MARS. This Japanese version of MARS can be used as a standard to evaluate the quality and credibility of mHealth apps.
The Use of Electronic Consultations in Outpatient Surgery Clinics: Synthesized Narrative Review (Preprint)
Authors: Payne Thomas , Kevric Jasmina , Stelmach Wanda , To Henry
Published: April 2022

BACKGROUND

Electronic consultations (eConsults) are an increasingly used form of telemedicine that allows a nonspecialist clinician to seek specialist advice remotely without direct patient-specialist communication. Surgical clinics may see benefits from such forms of communication but face challenges with the need for intervention planning.

OBJECTIVE

We aimed to use the Quadruple Aim Framework to integrate published knowledge of surgical outpatient eConsults with regard to efficacy, safety, limitations, and evolving use in the era of COVID-19.

METHODS

We systematically searched for relevant studies across four databases (Ovid MEDLINE, Embase, Scopus, and Web of Science) on November 4, 2021, with the following inclusion criteria: English language, published in the past 10 years, and data on the outcomes of outpatient surgical eConsults.

RESULTS

A total of 363 studies were screened for eligibility, of which 33 (9.1%) were included. Most of the included studies were from the United States (23/33, 70%) and Canada (7/33, 21%), with a predominant multidisciplinary focus (9/33, 27%). Most were retrospective audits (16/33, 48%), with 15% (5/33) of the studies having a prospective component.

CONCLUSIONS

The surgical eConsult studies indicated a possible benefit for population health, promising safety results, enhanced patient and clinician experience, and cost savings compared with the traditional face-to-face surgical referral pathway. Their use appeared to be more favorable in some surgical subspecialties, and the overall efficacy was similar to that of medical subspecialties. Limited data on their long-term safety and use during the COVID-19 pandemic were identified, and this should be the focus of future research.
IDENTIFICATION OF POTENTIAL COX-2 INHIBITORS FROM PHYTOCHEMICAL CONSTITUENTS OF INDIAN “GARAM MASALA” USING IN SILICO ANALYSIS
Authors: DEY SASWATA , BUWA VAEESHNAVI
Published: April 2022

Objective: The objective of the study was to analyze the active principles of “Garam Masala” (routinely used spice-mix in Indian cuisine) for their anti-inflammatory potential against Cyclooxygenase-2 (COX-2), a crucial player in inflammatory response in humans, using molecular docking simulation.
Methods: After obtaining three-dimensional structures of spice phytochemicals and COX-2 protein from PUBCHEM and PDB databases, phytochemicals with suitable absorption, distribution, metabolism, and excretion (ADME) properties were docked against COX-2 protein using PyRx and AutoDock tools 1.5.6 and their binding properties were compared with “Coxibs” drugs (NSAIDs, known COX-2 inhibitors) to establish their anti-COX-2 potential.
Results: Farnesiferol A showed better binding affinity to COX-2 whereas three other phytochemicals Piperine, Cedrelanol, and Usnic acid demonstrated comparable binding affinity like those of “coxibs.”
Conclusion: Molecular docking simulation and ADME analysis reveal that Farnesiferol A, Piperine, Cedrelanol, and Usnic acid could be considered for potential drug candidates for COX-2 inhibition due to their promising binding affinities with COX-2.
TREATMENT OF EXTRA-VIRGIN OLIVE OIL ON ETHANOL- AND BENZENE-INDUCED ACINAR CELLS DAMAGE IN ADULT WISTAR RATS
Authors: ADEBOLA ADETUNJI OPEYEMI , TOMILOLA ADERUPOKO IDAYAT , ADEGOKE ADETUNJI OLUWASEYI , TOSIN OGUNBIYI BABAFEMI , TOYIN ADETUNJI IYABODE , LINDA NWOBI NNENNA , ESTHER OGUNBIYI OLUBUNMI , CHIGBOGU NWOBI JOSEPH , ROLAND BEJIDE AYODELE
Published: April 2022

Objective: The study is focused on the effect ethanol and benzene on the acinar cells and extra- virgin olive oil (EVOO) as an ameliorative agent.
Methods: Forty-eight Wistar rats were divided into eight groups of six animals per group: (1) Control group (a placebo of water), (2) EVOO, (3) 25% ethanol, (4) 200 mg/kg benzene, (5) 25% ethanol+200 mg/kg benzene (EB), (6) 25% ethanol+EVOO (EO), (7) 200 mg/kg benzene+EVOO (BO), and (8) 25% ethanol+200 mg/kg benzene+EVOO (EBO). The ethanol, benzene, and EVOO were administered orally.
Results: All the treatment groups lost body weight except Groups 1 and 2. The histology of the pancreas showed significant (p≤0.05) damage to the acinar cells of groups exposed to 25% ethanol, 200 mg/kg benzene, and EB when compared to the control, EVOO, EO, BO, and EBO. The enzymatic activities of amylase and lipase evaluated showed significant (p≤0.05) decrease in EO and BO as compared to 25% ethanol, 200 mg/kg benzene, and EB-treated groups.
Conclusion: There was an elevated glucose concentration in 25% ethanol and EBO as compared to control and EVOO has anti-inflammatory potential across the ameliorated groups.
PREVALENCE OF VOLUNTARY COUNSELING AND TESTING SERVICE UTILIZATION AND ITS ASSOCIATED FACTORS AMONG PREPARATORY SCHOOL STUDENTS IN GONDAR TOWN, AMHARA REGION, ETHIOPIA
Authors: DEMEKE GETANEH BIZUAYEHU , ALAZBIH NEGA MIHRET
Published: April 2022

Objectives: The objective of this study was to assess the prevalence of voluntary counseling and testing (VCT) services utilization and associated factors among preparatory school students in Gondar town, Amhara region, Ethiopia.
Methods: Institutional based cross-sectional study design was employed. Multistage sampling procedure was conducted. Data were collected using pre-tested self-administered questionnaire and the data were entered, clean, and analyzed using SPSS software. Descriptive, bivariate, and multivariate analysis were employed. Multivariate analysis with 95% CI was computed to identify factors associated with VCT service utilization at p<0.05.
Results: The study included a total of 654 study participants, with a response rate of 97%. According to the research, 48.3% of adolescents used VCT services (95% CI: 44.5–52.1). The results of multivariate analysis revealed that age, site of birth, mother education, and discussion with parents were all substantially associated with the use of VCT services.
Conclusions: The majority of those who took part in the survey did not use VCT services. Only a small percentage of respondents have ever taken a VCT test and discussed it with their parents. The primary barrier for adolescents in the study area was cultural taboos, which they did not discuss with their parents. As a result, it will take an endless amount of effort from all relevant parties to promote teenage service use, as well as family life education, to encourage students and parents to use VCT.
AN ANALYSIS OF LANGUAGE STYLE IN THE RON CLARK STORY MOVIE
Authors: APRILIA RIZKA , SAYIDWIJAYA M. , REFYTAWATI DIAN
Published: April 2022

This study focused on analyzing language style in The Ron Clark Story movie. This study was analyzing types of language style by Joos are frozen style, formal style, consultative style, casual style, and intimate style. It was conducted using a qualitative research design and used a descriptive method to finding different language styles. The data of this research are language style by Joos and the data source is The Ron Clark Story movie. The steps to collect the data were: Downloaded the movie and searched the script of the movie. The data from The Ron Clark Story movie identified and selected to indicating of language style, classified, and analyzed the data, found the factors of different styles, and concluded. The result of this research found 90 data or 57.3% casual style, 46 data or 29.3% consultative style, 13 or 8.3% formal style, and 8 data or 5.1% intimate style.
СМАРТ-ДИСПЛЕИ RayStar ДЛЯ ПРОМЫШЛЕННОГО ПРИМЕНЕНИЯ
Authors: Павленко А.
Published: April 2022

Представлена линейка смарт-­дисплеев тайваньской компании RayStar, которые широко применяются в решениях потребительского рынка, системах управления производственными линиями, энергетической сфере, автомобильной промышленности.
ТЕСТОВЫЕ И КАЛИБРОВОЧНЫЕ СИСТЕМЫ ДЛЯ СЧИТЫВАЮЩЕЙ ЭЛЕКТРОНИКИ КРЕМНИЕВЫХ ДЕТЕКТОРОВ. Часть 2
Authors: Воронин А. , Кудряшов И.
Published: April 2022

Во второй части статьи рассмотрены тестовые системы и аппаратно-­программные комплексы для контроля считывающей электроники кремниевых детекторов, применяемой в различных экспериментах физики высоких энергий и физики космических лучей.
МЫ ГОТОВЫ ОБЕСПЕЧИТЬ ВСЮ ОТЕЧЕСТВЕННУЮ ПРОМЫШЛЕННОСТЬ АНАЛИЗАТОРАМИ ЦЕПЕЙ
Authors: Заостровных С. , Сучков Е.
Published: April 2022

ООО «ПЛАНАР» – одно из ведущих российских предприятий,
специализирующихся в области телекоммуникационной и контрольно-измерительной
аппаратуры. В ассортимент продукции компании входит
оборудование для построения сетей кабельного телевидения (головные
станции, усилители, фильтры, распределители) и измерительные
приборы СВЧ-диапазона (векторные анализаторы цепей, автоматические
калибровочные модули, измерители для эфирного, кабельного
и спутникового телевидения). Собственные производственные мощности
компании соответствуют мировым стандартам, что обеспечивает высокое
качество выпускаемой продукции. Созданные на базе современных
технологий приборы востребованы как в России, так и за рубежом, причем
львиная доля изделий до недавнего времени поставлялась иностранным
заказчикам. Сегодня компания приняла решение ориентироваться
в первую очередь на внутренний рынок – знаковым событием в этой
связи стало открытие в марте 2022 года в Санкт-Петербурге
первого регионального офиса ООО «ПЛАНАР» в России. На мероприятии,
посвященном открытию нового офиса, мы побеседовали с директором
ООО «ПЛАНАР» Сергеем Александровичем Заостровных и руководителем
представительства ООО «ПЛАНАР» в Санкт-Петербурге
Евгением Сергеевичем Сучковым.
КАК ИНТЕРЕС К ТЕХНИКЕ СТАНОВИТСЯ БИЗНЕСОМ
Authors: Меньшиков Я.
Published: April 2022

Компания «Яростанмаш», специализирующаяся
на разработке анализаторов химических
источников тока, является примером того,
как может найти приложение и привести
к успеху интерес к технике и стремление
реализовывать свои идеи. Ее основатель
и технический директор Ярослав Андреевич
Меньшиков рассказал нам о том, как появилась
данная компания, почему для нее стало
основным именно направление испытательных
приборов для суперконденсаторов
и аккумуляторов, и поделился некоторыми
соображениями по применению различных
источников питания, основанными на опыте
их тестирования.
ОБНОВЛЕНИЕ ПАРКА ОБОРУДОВАНИЯ ДЛЯ ПРОИЗВОДСТВА КЕРАМИЧЕСКИХ КОНДЕНСАТОРОВ – ОДИН ИЗ ШАГОВ К ОСВОЕНИЮ НОВЫХ ГОРИЗОНТОВ МИНИАТЮРИЗАЦИИ ВИЗИТ НА ПРОИЗВОДСТВО ООО «КУЛОН»
Authors: Миронюк В.
Published: April 2022

Расположенное в Санкт-Петербурге ООО «Кулон» известно как один
из крупнейших производителей пассивных электронных компонентов.
Предприятие многие годы успешно выпускает керамические конденсаторы
и проходные фильтры, которые применяются как в военной и специальной
технике, так и в аппаратуре народно-хозяйственного
назначения.
РАЗРАБОТКА ФУНКЦИОНАЛЬНОЙ СХЕМЫ 8 РАЗРЯДНОГО АЦП ПОСЛЕДОВАТЕЛЬНОГО ПРИБЛИЖЕНИЯ В САПР OrCAD C ИСПОЛЬЗОВАНИЕМ МАКРОМОДЕЛЕЙ
Authors: Строгонов А. , Худяков Ю. , Белых М.
Published: April 2022

Моделирование электрических схем с применением современных САПР позволяет исследовать работу схемы без необходимости изготовления прототипа. В статье рассмотрен пример реализации функциональной схемы АЦП последовательного приближения в САПР OrCAD с использованием макромоделей ИС.
ВСЕСТОРОННИЙ АНАЛИЗ ТОПОЛОГИИ ПЕЧАТНОЙ ПЛАТЫ В Altair PollEx ДЛЯ ALTIUM DESIGNER. Часть 1.
Authors: Евграфов А.
Published: April 2022

В статье рассмотрены возможности Altair PollEx – программного решения компании Altair Engineering, предназначенного для анализа и верификации печатных плат на любой стадии проектирования.
Синтез и исследование свойств N-дифенилфосфорил-N'- алкилмочевин как нового класса экстрагентов для концентрирования и разделения урана и трансурановых элементов
Authors: Сафиулина А.М. , Лизунов А.В. , Семенов А.А. , Горюнов Е.И. , Горюнова И.Б. , Баулина Т.В. , Моргалюк В.П. , Брель В.К. , Тананаев И.Г.
Published: April 2022

Проведено квантово-химическое моделирование структуры N-дифенилфосфорил-N’-(
ω-алкил)мочевин на основе расчета молекулярных электростатических полей.
Разработан высокоэффективный технологичный one-pot-синтез и синтезиро-
ваны N-дифенилфосфорил-N’-(ω-алкил)мочевины. Исследованы экстракцион-
ные свойства по отношению к f-элементам в азотнокислых средах. Показано, что
N’-алкилзамещенные N-дифенилфосфорилмочевины являются высокоэффектив-
ными экстрагентами, способными извлекать актиноиды и лантаноиды из азотнокис-
лых растворов с высокими коэффициентами распределения, существенно превос-
ходя при этом известные нейтральные моно- и бидентатные фосфорорганические
экстрагенты различных типов.
Химия как совокупность рекордных достижений
Authors: Мильман Б.Л.
Published: April 2022

Статья представляет собой обзор рекордов химии – самых больших или малых
молекул, их предельных свойств и характеристик, примечательных фактов и дости-
жений химиков, «самого-самого » в этой науке. Обсуждается значение и смысл науч-
ных рекордов. Их совокупность выпукло демонстрирует роль химии в науке, техно-
логии и материальной культуре человечества.
Experimental study on rutting performance by using polypropylene fiber
Authors: Naz Falak , Kui Dr. Hu , . Anwar , . Zakir
Published: April 2022

Abstract: Transportation engineering play a vital role in the developing of a society and a country. It’s actually deal with the planning, designing, operating and managing different types of facilities for all modes of transportation to provide safe, convenient, comfortable, efficient and economical movement of people as well as goods. Due to the climatic variations and growth of traffic loading, road infrastructure faces number of serious failures such as rutting, stripping, fatigue cracking, bleeding etc. Maintenance of roads is necessary because roads lose its serviceability with passage of time. A lot of researches have been done to improve the quality of hot mix asphalt and to overcome problems associated with HMA. In current research polypropylene fibers were used as additive in asphalt concrete at different percentages i.e., 1%, 2%, 3% by weight of total mix. The main target of this study was to check the effect of polypropylene fibers on the rutting performance of HMA and also to check the response of fibers modified samples against moisture damage. For mixing of fibers with Hot Mix Asphalt “wet method” of mixing was adopted. For determination of OBC Marshall Mix Design was followed. Same OBC was used for control and fibers modified samples. Wheel tracker test and indirect tensile test were carried out for determination of rutting and moisture susceptibility of different mixes respectively. On the basis of rutting test result, it was revealed that adding 1% polypropylene fibers enhanced the ability of hot mix asphalt to resist rutting up to 14%, while for 2% and 3% fibers decrease in rutting resistance was noted which was 18% and 78% respectively. From the results of indirect tensile strength, it was observed that resistance to moisture damage is increases by increasing the quantity of fibers because it has maximum elongation and modulus as compared to bitumen. Keywords: Polypropylene Fibers, Wheel Tracker test, Indirect Tensile Test, Marshall Mix
Localized Network Reconfiguration Plan for Wireless Mesh Networks
Authors: Pulyala Ranjith
Published: April 2022

Abstract: Wireless mesh networks (WMNs) have emerged as a key technology for next-generation wireless networking. Because of their advantages over other wireless networks, WMNs are undergoing rapid progress and inspiring numerous applications. In multi-hop wireless mesh networks (WMNs) experience frequent link failures caused by channel interference, dynamic obstacles and/or applications’ bandwidth demands. These failures cause severe performance degradation in WMNs or require expensive, manual network management for their real-time recovery. This paper presents an Autonomous network Reconfiguration System (ARS) that enables a multi-radio WMN to autonomously recover from local link failures to preserve network performance. ARS also improves channel efficiency by more than 90% over the other recovery methods. During their lifetime, multi-hop wireless mesh networks (WMNs) experience frequent link failures caused by channel interference, dynamic obstacles, and/or applications’ bandwidth demands. These failures cause severe performance degradation in WMNs or require expensive manual network management for their real-time recovery. By using channel and radio diversities in WMNs, ARS generates necessary changes in local radio and channel assignments in order to recover from failures. Next, based on the thus-generated configuration changes, the system cooperatively reconfigures network settings among local mesh routers. ARS has been evaluated extensively through ns2-based simulation. Our evaluation results show that ARS outperforms existing failure-recovery schemes in improving channel-efficiency by more than 90% and in the ability of meeting the applications’ bandwidth demands by an average of 200%. Keywords: WMN, ARS, AODV, WCETT, ETT, RSVP, DSDV, ETX, ETOPE, BLC
Optimization and Development of Existing Corn Sheller Machine
Authors: Mujbaile Vedanand , Shindekar Aditya , Tidke Mayur , Jiwankar Shronit , Bramhapurikar Karan , Kakde Chhaya , Dhepe Pratik
Published: April 2022

Abstract: In our country, most of the land use for the agriculture purpose that manufacture semi-finish product or product. Farmers in developing country like Republic of India grows little scale maze. Corn is sold-out by farmer with cob. the typical kernel value is just about double the value of cob. maze is extremely helpful plant for man and animal. it's a serious material for business particularly for production of starch, oil, protein, food sweeteners and bio fuels. it's process is effortful and time intense. This mobile machine was designed to shell maize and to separate the cob from the grain. The additional financial gain is generated by farmers if corns is embellished and kernels area unit sold-out on the market themselves. however this needs a worker of low cost operated by hand and economical maize. the shortage of little maize process machine i.e, maize worker is that the major maize production downside, particularly in our country Republic of India.
Covid-19 Dissemination: Late Contact in Local Centers in Southeastern Tocantins
Authors: Pacífico Filho Miguel , Iwamoto Helga Midori , Borges Thelma Pontes , Cançado Airton Cardoso
Published: April 2022

In 2020, the world was overwhelmed by COVID-19, which produced a severe pathology with high mortality rates. National policies to control the pandemic clashed with Brazil’s precarious health structure. While the Brazilian state of Tocantins, along with the rest of the world, saw its main cities suffer from high contamination rates, certain other localities remained free from these dynamics for a much longer period. Thus, this study set out to investigate five municipalities, all located in the southeastern corner of the state, and which were the last to be affected by the pandemic. The aim was to reflect upon the factors that delayed the arrival of the virus. A descriptive analysis was conducted, with a bibliographical review and the use of secondary data from the Instituto Brasileiro de Geografia e Estatística (IBGE) database, the State Department of Planning and Budget, epidemiological bulletins from the Department of Health, indices from the agribusiness production chain and the industrial profile, produced by the Tocantins State Federation of Industries. It was concluded that certain factors contributed to this process, such as a low level of influence from urban centers, a lack of major highways and the low purchasing power of the population, which avoided greater flows resulting from the low economic attractiveness.
Disseminação da COVID-19: contágio tardio em centros locais no sudeste do Tocantins
Authors: Pacifico Filho Miguel , Iwamoto Helga Midori , Borges Thelma Pontes , Cançado Airton Cardoso
Published: April 2022

O mundo foi assolado em 2020 pela COVID-19, geradora de patologia grave com alta mortalidade. As políticas nacionais de controle da pandemia esbarraram na precária estrutura sanitária do país. O Tocantins, acompanhando o restante do mundo, viu suas principais cidades sofrerem com índices de contaminação; contudo, determinadas localidades se viram livres dessa dinâmica por um período maior. É sobre o estudo de cinco municípios, localizados no sudeste do estado, os últimos a serem atingidas pela pandemia, que esse trabalho versa, com o objetivo de refletir sobre fatores que retardaram a chegada do vírus. Foi realizada pesquisa descritivo-analítica, com revisão bibliográfica e o uso de dados secundários em bases do IBGE, da Secretaria do Planejamento e Orçamento do estado, bem como de boletins epidemiológicos da Secretaria da Saúde, índices da cadeia produtiva do agronegócio e perfil da indústria, produzidos pela Federação das Indústrias do Estado do Tocantins. Concluiu-se que alguns fatores contribuíram para esse processo, como a baixa influência de centros urbanos, a não incidência de grandes rodovias e o baixo poder aquisitivo da população, o que evitou maiores fluxos resultantes da baixa atratividade econômica.
Política habitacional no Brasil: manifestações territoriais de uma década de habitação social de mercado
Authors: Nascimento Neto Paulo , Ultramari Clovis
Published: April 2022

Observa-se atualmente um cenário de inflexões na política habitacional brasileira: princípios, narrativas e instrumentos até então amplamente disseminados são alterados ou suprimidos. O Programa Minha Casa Minha Vida, emblemático da atuação pública da última década, insere-se nesse contexto e sugere o encerramento de um ciclo. Com esse pressuposto, o artigo investiga os padrões de distribuição regional dos empreendimentos produzidos no âmbito do programa com base em uma abordagem supramunicipal, tendo como recorte de análise o território estadual. Por meio de um estudo de caso no estado do Paraná, os resultados do referido programa são avaliados e seus clusters regionais de atendimento são identificados. As conclusões ampliam a compreensão dos estudos realizados em contextos municipais e metropolitanos específicos, evidenciam arranjos regionais diversos daqueles de corte metropolitano e apontam para uma nova agenda de pesquisas, em um contexto no qual conteúdos programáticos e princípios são reformatados.
Effect of Countermovement and Arm Swing on Vertical Stiffness and Jump Performance
Authors: Shadmehr Azadeh , Hejazia S. Maryam , Olyaei Gholamreza , Talebian Saeid
Published: April 2022

Objectives To determine the effect of using arm swing and countermovement on vertical stiffness and maximum vertical jump performance. Participants A total of 25 young healthy females were participated in the study. They stood on the force plate and performed two models of squat jump with (SJA) and without arm swing (SJ) and two models of countermovement jump with (CMJA) and without arm swing (CMJ).Main outcome measures Vertical leg stiffness, jump height, flight time, contact time and power were compared in SJ, SJA, CMJ and CMJA.Results In the CMJs, the stiffness and jump height were significantly higher than SJA and SJ. Contact time in jumps with countermovement and/or arm swing was three times lower than SJA and SJ.Conclusion Vertical stiffness and performance parameters can be improved by using countermovement and arm swing during vertical jump and due to enhancement in work output and ground reaction force.
CARDIAC RADIOLOGY
Authors: Editorial Article
Published: April 2022

.
IMAGING IN OBSTETRICS AND GYNECOLOGY
Authors: Editorial Article
Published: April 2022

.
NEURORADIOLOGY
Authors: Editorial Article
Published: April 2022

.
IMAGING IN ONCOLOGY
Authors: Editorial Article
Published: April 2022

.
CRITICAL LEGAL STUDIES (CLS): AN ALTERNATIVE FOR CRITICAL LEGAL THINKING IN INDONESIA
Authors: Ali Safa’at Muchamad , Istiqomah Milda
Published: April 2022

This article discusses Critical Legal Studies (CLS) as the critical study of the law that opposes the doctrine of legal formalism. As a form of critical study, CLS not only accommodates Marxist legal ideas, but also liberalist-radical and postmodernist ones. This article has the objective to identify briefly the ideas contained within CLS from various legal experts, its advantages and disadvantages, as well as its context with the legal development in Indonesia. The utilized research method was the normative method for the investigation and analysis of the existence of legal doctrines. This article concludes with a critique of the law in Indonesia at present and how the ideas of CLS may be utilized as another radical alternative in solving legal problems in Indonesia.

Abstrak: Artikel ini membahas mengenai Critical Legal Studies (CLS) sebagai studi kritis hukum yang menentang doktrin formalisme hukum. Sebagai bentuk kajian kritis, CLS tidak hanya menampung ide-ide hukum Marxis, tetapi juga liberalis-radikal dan postmodernis. Artikel ini bertujuan untuk mengidentifikasi secara singkat gagasan-gagasan yang terkandung dalam CLS dari berbagai pakar hukum, kelebihan dan kekurangannya, serta konteksnya dengan perkembangan hukum di Indonesia. Metode penelitian yang digunakan adalah metode normatif untuk mengkaji dan menganalisis keberadaan doktrin-doktrin hukum. Artikel ini diakhiri dengan kritik terhadap hukum di Indonesia saat ini dan bagaimana gagasan CLS dapat dimanfaatkan sebagai alternatif radikal lain dalam menyelesaikan permasalahan hukum di Indonesia.

Kata Kunci: Studi Kritis Hukum, Doktrin Formalisme Hukum, Alternatif Radikal.
Novel Binomial Series and its Summations
Authors: Annamalai Chinnaraji
Published: April 2022

This paper presents innovative series and summations derived from the
optimized combinations relating to the combinatorics. These series and
summations will be useful for the researchers who are involving to solve
the scientific problems.
Anomaly recognition method of perception system for autonomous vehicles based on distance metric
Authors: Shao Cuiping , Chen Beizhang , MIAO ZU , Cui Yunduan , Li Huiyun
Published: April 2022

Environmental perception system is the premise of the safety and
stability of the autonomous vehicle system. However, studies have shown
that the on-board sensors included in the perception system are
extremely vulnerable to external attacks and interference, leading to
incorrect driving strategies and bringing great security threats. Aiming
at the problem, this paper divides the vehicle-mounted sensors into a
positioning group and an identification group according to their role in
the perception system. Then, based on the information correlation
between sensors in the same group and the information correlation of a
single sensor on adjacent time series, the distance metric model between
sensors in a group and the distance metric model for each sensor of this
group on time series is established. And the normal distance intervals
corresponding to the confidence interval are calculated respectively.
According to the distance metric model between sensors, we can detect
anomalies in the perception system in real-time. Further, according to
the distance metric model for each sensor on adjacent time series, we
can identify anomaly sensors. Our experimental results quantitatively
show that the method achieves real-time anomaly recognition, and
demonstrate the effectiveness and robustness of the method on the
open-source KITTI dataset.
Acetaminophen, a therapeutic or an extremely toxic remedy – a review
Authors: Caragea Genica , Avram Oana , Pauna Andreea , Costea Andreea , Tudosie Miruna
Published: April 2022

When a new coronavirus appeared in the late 2019, identified as the cause of several cases of pneumonia in Wuhan, Paracetamol was initially reported to be the preferable antipyretic medication, choice which was detrimental to the use of other drugs. People have resorted to buying large stocks of Paracetamol and some have used it in large doses, regardless of the consequences. However, the Paracetamol (Acetaminophen) overdose remains the leading cause of death or transplantation due to acute liver failure in many parts of the world. This review aims at presenting the pharmacokinetics, the clinical signs, and the risk factors for systemic toxicity associated with Paracetamol overdose, as well as the current therapeutic approach. Paracetamol is primarily metabolized in the liver, by glucuronidation and sulfation. In case of a Paracetamol overdose, a large amount of NAPQI is conjugated with glutathione, and this process is due to a major depletion of glutathione, thus leading to hepatic necrosis, renal failure, and encephalopathy. The evaluation of serum acetaminophen levels by analytical methods is extremely useful both for the diagnosis and the therapy monitoring.
Colonic diverticulosis - diagnostic and therapeutic difficulties
Authors: Meșină Cristian , Dumitrescu Theodor , Ciorbagiu Mihai , Obleaga Cosmin , Vilcea Ionica , Mesina-Botoran Mihaela
Published: April 2022

Objectives. The objectives of this study are to highlight the diagnostic and therapeutic difficulties in patients with complicated acute colonic diverticulosis. Methods. The study group comprised 40 patients hospitalized to the Second Surgical Clinic of the Emergency County Hospital in Craiova, Romania, through the emergency service between 2015 and 2021. Regarding the sex distribution of the patients with colonic diverticular disease studied, there was a predominance of males. The distribution of patients was as follows: 22 patients with acute colonic diverticulitis, out of whom 21 patients suffered from left acute colonic diverticulitis and 1 patient suffered from right acute colonic diverticulitis. Results. The diagnosis of acute colonic diverticulitis was made by corroborating the data obtained on the objective clinical examination with the data obtained by exploring the abdomen by means of computed tomography, which revealed a thickening of the colon wall (acute sigmoid diverticulitis predominated). The treatment applied to patients with acute diverticulitis was conservative and in patients with acute perforated colonic diverticulitis, the treatment of choice was the surgical one. Mortality was 7.5% of all the cases. Conclusions. In patients with perforated colonic diverticular disease, the administered treatment consisted in Hartmann segmental colectomy, wound care, peritoneal drainage. The reintegration of the colon in the digestive transit was performed after 3-6 months.
The customized therapeutic approach of a giant pancreatic pseudocyst. A case report and literature review
Authors: Banu Petrișor , Socea Bogdan , Balan Daniela , Sandu Vladimir , Onicel Tiberiu , Silaghi Adrian , Paunica Ioana , Constantin Vlad
Published: April 2022

Giant pancreatic pseudocysts are considered those cysts whose dimensions exceed 10 cm and are sporadically reported in the literature. Although there are multiple treatment modalities, there are currently no treatment guidelines or consensus on the best therapeutic approach for giant pancreatic pseudocysts. We report the case of a 32-year-old male patient with a giant pancreatic pseudocyst after an episode of acute pancreatitis, which was treated by internal surgical drainage through cyst-jejunal anastomosis. This surgical procedure was followed by the formation of a retroperitoneal abscess which was resolved by ultrasound-guided drainage. The subsequent evolution of the patient was favorable, without other complications. Given their complex anatomical relations, the treatment of giant pseudocysts requires strategies adapted to the local conditions. The optimal choice of the operative time and of the therapeutic strategy is based on clinical considerations and the effectiveness of the method used can be assessed by a long-term follow-up.
Inflammatory bowel disease: pathogenesis, diagnosis and current therapeutic approach
Authors: Silaghi Adrian , Constantin Vlad , Socea Bogdan , Banu Petrișor , Sandu Vladimir , Andronache Liliana , Dumitriu Anca , Paunica Stana
Published: April 2022

Inflammatory bowel disease is a group of conditions of unknown etiology, represented by Crohn’s disease and ulcerative colitis and characterized by the presence of intestinal wall inflammation. From the first cases described to date, several studies have been performed to elucidate the cause of inflammatory bowel disease. Generally, the genetic factors predispose to their occurrence while epigenetic and environmental factors trigger them. Genetic factors are mutations of the genes involved in the response and recognition of immune cells to different pathogens. The most studied epigenetic and environmental factors are smoking (which predisposes to Crohn’s disease and can be protective for ulcerative colitis), lack of vitamin D, a diet rich in sugars and low in flavonoids and fibers. The diagnosis is usually established by endoscopy and biopsy. Recent technologies can perform live biopsies such as endocytoscopy or confocal laser endomicroscopy, with an accuracy of 100% compared to classical methods. Therapy involves several classes of drugs, preferably in association with diet and lifestyle changes. In case of complications or in non-responsive diseases, surgery must be considered, as documented for ulcerative colitis that can be cured by removing the entire colon. The purpose of this review is to present recent findings on pathology, as well as modern diagnosis and treatment methods for IBD.
Vitamin D deficiency in thyroid autoimmune diseases
Authors:   ”Victor Papilian” Faculty of Medicine, „Lucian Blaga” University Sibiu, Romania, Lebădă Ioana-Codruța , Ristea Ruxandra ,   County Emergency Clinical Hospital, Sibiu, Romania, Metiu Maria ,   ”Victor Papilian” Faculty of Medicine, „Lucian Blaga” University Sibiu, Romania
Published: April 2022

The role of vitamin D in the human body is a complex one, proven by the many studies performed related to this aspect. Data from the literature on the correlation between vitamin D deficiency and thyroid autoimmune pathology, although present and increasing in the last 10 years, have failed to establish exactly whether or not there is a link between them. The aim of the study was to assess the status of vitamin D in patients with autoimmune thyroid disease; and to determine if there is a correlation between parameters such as: thyroid stimulating hormone (TSH), free thyroxine (FT4), ATPO; and vitamin D levels. Therefore, we performed a retrospective study in which we included 60 patients, 32 with autoimmune thyroid pathology and 28 patients with negative antithyroid antibodies. The average age of those in the case group was 58 years old and 52 years old for the control group. Female sex was predominant in both groups of patients, 97% in the study group and 71% in the control group. Vitamin D values ​​in patients with thyroid autoimmune pathology in our study were on average higher than those obtained in the control group (patients with negative thyroid antibodies), without finding a statistically significant difference between the values ​​of the two groups of patients (p = 0.197). The study shows a high prevalence of vitamin D deficiency in both groups of patients (with or without autoimmune thyroid disease), the highest rate being observed among patients without autoimmune pathology, but without a statistically significant difference between values.
Causes of Conflict and Organizational Productivity in Deposit Money Banks in Ekiti State, Nigeria
Authors:   Department of Business Administration,  Bamidele Olumilua University of Science, Technology and Education,  Ikere Ekiti, Ekiti State, Nigeria, Adebowale Israel Olukayode (Ph.D)
Published: April 2022

The study examined causes of conflict and organizational productivity in all deposit money banks in Ekiti state. The study adopted a descriptive survey research design. The population of the study consists of 773 members of staff in all deposit money banks in Ekiti state; this was also used as sample. A well structure questionnaire was used to collect data for the study. The face and content validity of the instrument was ensured. The data collected from the pilot study was subjected to reliability test using Cronbach’s Alpha techniques and reliability co-efficient 0.80 was obtained therefore the instrument was reliable to collect relevant information for the study. 58 of the questionnaire distributed were not returned as some were not properly filled. The research question was analysed descriptively. Analysis of covariance (ANCOVA) was used to test the hypothesis formulated at 0.05 level of significance. The study identified causes of conflict such as improper handling of conflict, when strategies or styles in handling conflict are faulty, slow response time to conflict in an organization, policies on compensation/rewards are anti-employees, instability of tenure of staffers could also result to conflict just to mention few, it is concluded that that gender, marital status and educational qualification of employees are significantly responsible for conflict in an organization. It therefore recommended that organizations should co-opt some salient opinions of their employees thereby making adequate room for participation in decision making in order words participatory, rather than autocratic style of management, should be encouraged by organization. Conflict, Productivity, Employees, Employers, Organisation
Socio-endocrinology revisited: New tools to tackle old questions
Authors:   , Christensen Charlotte
Published: April 2022

Animals’ social environments impact their health and survival, but the proximate links between sociality and fitness are still not fully understood. In this thesis, I develop and apply new approaches to address an outstanding question within this sociality-fitness link: does grooming (a widely studied, positive social interaction) directly affect glucocorticoid concentrations (GCs; a group of steroid hormones indicating physiological stress) in a wild primate? To date, negative, long-term correlations between grooming and GCs have been found, but the logistical difficulties of studying proximate mechanisms in the wild leave knowledge gaps regarding the short-term, causal mechanisms that underpin this relationship. New technologies, such as collar-mounted tri-axial accelerometers, can provide the continuous behavioural data required to match grooming to non-invasive GC measures (Chapter 1). Using Chacma baboons (Papio ursinus) living on the Cape Peninsula, South Africa as a model system, I identify giving and receiving grooming using tri-axial accelerometers and supervised machine learning methods, with high overall accuracy (~80%) (Chapter 2). I then test what socio-ecological variables predict variation in faecal and urinary GCs (fGCs and uGCs) (Chapter 3). Shorter and rainy days are associated with higher fGCs and uGCs, respectively, suggesting that environmental conditions may impose stressors in the form of temporal bottlenecks. Indeed, I find that short days and days with more rain-hours are associated with reduced giving grooming (Chapter 4), and that this reduction is characterised by fewer and shorter grooming bouts. Finally, I test whether grooming predicts GCs, and find that while there is a long-term negative correlation between grooming and GCs, grooming in the short-term, in particular giving grooming, is associated with higher fGCs and uGCs (Chapter 5). I end with a discussion on how the new tools I applied have enabled me to advance our understanding of sociality and stress in primate social systems (Chapter 6).