bluuebunny/crossref_metadata_2025 huggingface dataset:
Tasca e sacca: geosinonimi parziali
Authors: Di Bonito Cristiana
Published: May 2023

Ci sono pervenute varie richieste di chiarimento sulla distinzione tra tasca e sacca.
A PROSPECTIVE OBSERVATIONAL STUDY OF RESPONSE TO NEOADJUVANT CHEMOTHERAPY IN LOCALLY ADVANCED BREAST CANCER IN TERTIARY CENTRE
Authors: Sarkar Manojit , Kumar Saha Asis
Published: May 2023

Introduction: Carcinoma of the breast from the very beginning has been a feared disease.' Till today, there is an aura of
fear that surrounds the mention of this name 'breast cancer'. Neoadjuvant chemotherapy (NAC) is increasingly used to
treat patients with locally advanced breast cancer (LABC). Such regimens can increase rates of breast-conserving therapy (BCT) compared with
post-operative chemotherapy 2 and may minimize the need for aggressive nodal surgery with axillary lymph node dissection. To assess Aims:
the change of clinical staging after Neoadjuvant Chemotherapy, Assessment of Lymph node status after neoadjuvant Chemotherapy and type of
surgery suitable after neoadjuvant Chemotherapy. The present study was a hospital Materials and method: based observational study. The
study conducted in Nil Ratan Sircar Medical College & Hospital. The study duration was One year (June 2021 to May 2022). 50 patients were
included in this study. In our study, all patients [50 (100.0%)] had Lymph node involvement. We Result: showed that, most of the patients had
Stage IIIA [25 (50.0%)]. However, Stage IIIB [15 (32.0%)] followed by Stage IIIC [10 (20.0%)] which was statistically signicant (p=.00168).It
was found that, all patients [50 (100.0%)] had Anterior Chemotherapy. Our study showed that, most of the patients had Stage IIB after
chemotherapy [22 (44.0%)] and it was statistically not signicant (p< .14706) (z=1.4499). In our study, higher number of patients had Down
stage Result [35 (70.0%)] followed by Same Result [15 (30.0%)] but this was statistically signicant (p=.00006) (z=4). We showed that, the
mean Tumor size of patients was [7.2880± 1.4822 (cm)] and mean % of size reduction of patients was [58.0000± 15.0509]. we Conclusion:
conclude that, the change of clinical staging after Neoadjuvant Chemotherapy, Lymph node status after neoadjuvant Chemotherapy
Selection of conditions for effective inactivation of Pseudopestis avium virus (Paramyxoviridae: Orthoavulovirus: Avian orthoavulovirus 1) for the production of a Newcastle disease vaccine
Authors: Jekebekov Kuanish K. , Assanzhanova Nurika N. , Nurpeisova Ainur S. , Ryskeldinova Sholpan Zh. , Absatova Zharkinay S. , Abay Zhandos S. , Shayakhmetov Yeraly A. , Omurtay Alisher D. , Moldagulova Sabina U. , Kalimolda Elina Zh. , Sadikalieva Sandugash O. , Shorayeva Kamshat A. , Zakarya Kunsulu D.
Published: May 2023

Introduction. Newcastle disease (ND) is classified as especially dangerous pathogen. Its primary source is an infected or recovered bird. The virus shedding begins just in a day after infection, and virus remains in the body for another 2-4 months after the recovery. The complexity of the final elimination of the causative agent of the disease lies in its ability for long-term preservation in the external environment and the possibility of constant circulation in one complex between groups of birds of different sex and age. Therefore, the main element of protecting birds from ND is immunoprophylaxis that is based on vaccines containing an inactivated ND virus (NDV).
The aim of the work ‒ is to optimize the parameters of inactivation of the NDV actual strain H with formaldehyde at final concentrations of 0.01, 0.025, 0.05, and 0.1% under temperature conditions of 20 2 and 37 0.5 C.
Materials and methods. We used a virus-containing suspension of the NDV strain H with an initial biological activity of 10.75 lg EID50/cm3 grown by cultivation in 10-day-old developing chick embryos.
Results. On the 16th day after the administration of the tested suspensions of NDV inactivated at different temperatures and concentrations of the inactivant , the geometric mean titers of antibodies to NDV in sera of vaccinated birds were at least 1 : 63 in the hemagglutination inhibition reaction, indicating that the studied inactivated suspensions were antigenically active.
Conclusion. The optimal parameters of the inactivation mode (final concentration, temperature and time of inactivation) of the NDV strain H were established. The inactivation process at 37 0.5 C with inactivant concentrations of 0.01, 0.025, 0.05, and 0.1% lasts up to 72, 22, 18, and 12 hours, respectively. The inactivation process at 20 2 C with inactivant concentrations of 0.05 and 0.1% lasts up to 22 and 18 hours, respectively.
Antigenic and immunogenic activity of virus-like particles based on rabbit hemorrhagic disease virus (Caliciviridae: Lagovirus) genotypes GI1 and GI2 recombinant major capsid proteins
Authors: Mukhin Aleksey N. , Alekseev Konstantin P. , Yuzhakov Anton G. , Selezneva Ekaterina V. , Moskvinа Anna S. , Verkhovsky Oleg A. , Aliper Taras I.
Published: May 2023

Introduction. Rabbit hemorrhagic disease is an acute highly contagious infection associated with two genotypes of pathogenic Lagovirus. Antibodies to major capsid protein (Vp60) are protective.
The aim of the work ‒ is an evaluation of antigenic and immunogenic activity of virus-like particles (VLPs) based on recombinant major capsid proteins of both genotypes of rabbit hemorrhagic disease virus (RHDV) (recVP60-GI1 and recVP60-GI2).
Materials and methods. Baculovirus-expressed VLPs were evaluated using electron microscopy and administered to clinically healthy 1.53 month old rabbits in a dose of 50 g. Rabbits were challenged with 103 LD50 of virulent strains Voronezhsky-87 and Tula 21 days post immunization. Serum samples were tested for the presence of RHDV-specific antibodies.
Results. VLPs with hemagglutination activity forming VLP 3040 nm in size were obtained in Hi-5 cell culture. Specific antibody titers in rabbits measured by ELISA were 1 : 200 to 1 : 800 on 21th day post immunization with VLPs. Immunogenic activity of recVP60-GI1 VLPs was 90 and 40%, while it was 30 and 100% for recVP60-GI2 VLPs after the challenge with RHDV genotypes 1 and 2 respectively. The immunogenicity of two VLPs in mixture reached 100%.
Discussion. VLPs possess hemagglutinating, antigenic and immunogenic activity, suggesting their use as components in substances designed for RHDV specific prophylaxis in rabbits. Results of the control challenge experiment demonstrated the need to include the antigens from both RHDV genotypes in the vaccine.
Conclusion. Recombinant proteins recVP60-GI1 and recVP60-GI2 form VLPs that possess hemagglutinating an antigenic activity, and provide 90100% level of protection for animals challenged with RHDV GI1 and GI2 virulent strains.
Business, Digitalization and Sustainability
Authors: - Chaitra Bocheer K S , - Aishwarya D
Published: May 2023

In the challenging context of COVID 19, the task of fostering business practices with digitalisation, sustainability, inclusion and diversity came into light. This report shows how these practices
as a whole are a powerful enabler of business performance.
Diseño y resultados de la encuesta sobre control de calidad de aceleradores lineales
Authors: Martínez Albaladejo Miguel , Vilches Pacheco Manuel , Almendral Manzano Pedro , Ambroa Rey Eva , Ferrer Gracia Carlos Luis , Pérez-Alija Fernández Jaime , Tortosa Oliver Ricardo , Lliso Valverde Françoise
Published: May 2023

En marzo de 2021, el grupo de trabajo sobre control de calidad de aceleradores de la Sociedad Española de Física Médica remitió a los servicios y unidades de radiofísica una encuesta en línea sobre algunos aspectos relacionados con el objeto de su trabajo. La encuesta se planteó con tres objetivos: ponderar la variabilidad en los planes de control de calidad, conocer el grado de adherencia a las recomendaciones nacionales e internacionales y sintonizar los criterios del grupo de trabajo con los de los servicios y unidades de radiofísica de nuestro ámbito.
Los resultados de la encuesta muestran una gran variabilidad de criterio en todos los aspectos y pruebas y confirman la dificultad de establecer un programa de control de calidad de estos equipos que responda a criterios objetivos de priorización y sea aplicable en todas las circunstancias existentes en nuestro ámbito.
Un programa de control de calidad debería establecerse sobre un análisis objetivo de los modos de fallo que permita decidir qué pruebas incluir, establecer los recursos necesarios y optimizar su utilización. Elaborar una recomendación de validez general no es sencillo, máxime si tenemos en cuenta la variedad existente en equipos, instrumentos y técnicas terapéuticas desarrolladas.
Data Interpretation Algorithm for Adaptive Methods of Modeling and Forecasting Time Series
Authors: Boyko Nataliya
Published: May 2023

The paper considers two forms of models: seasonal and non-seasonal analogues of oscillations. The paper analyzes the basic adaptive models: Brown, Holt, and autoregression. The parameters of adaptation and layout are considered by the method of numerical estimation of parameters. The mechanism of reflection of oscillatory (seasonal or cyclic) development of the studied process through a reproduction of the scheme of moving average and the scheme of autoregression is analyzed. The paper determines the optimal value of the smoothing coefficient through adaptive polynomial models of the first and second order. Prediction using the Winters model (exponential smoothing with multiplicative seasonality and linear growth) is proposed. The paper proves that the additive model allows building a model with multiplicative seasonality and exponential tendency. The paper proves statements that allow to choose the right method for better modeling and forecasting of data.
Introducción de los Principios del Estudio de Clases en Brasil: primeros pasos y grupos de estudio
Authors: Baldin Yuriko Yamamoto , Silva Aparecida Francisco da , Felix Thiago Francisco
Published: May 2023

En este artículo discutimos las bases que fundaron los estudios e iniciativas para implementar actividades del Lesson Study – Pesquisa de Aula (en portugués), considerando los principios originales del Lesson Study para contribuir a la mejora de las clases de matemáticas en las escuelas brasileñas. El estudio involucró un proyecto pionero de implementación en una escuela pública brasileña, a través de las actividades de investigación de un profesor en ejercicio, iniciando una línea de investigación en educación continua de maestros que enseñan matemáticas, basada en Lesson Study. Después de destacar la experiencia de investigación, este artículo sistematiza el progreso del proceso de implementación del Grupo de Estudio en la línea del Lesson Study, con el apoyo de los órganos educativos del estado de São Paulo, que representó el establecimiento de asociaciones de colaboración que consolidan las actividades de investigación aliadas a las prácticas en las escuelas de hoy. El artículo significa una síntesis del camino de implementación de los principios del Estudio de la Lección en Brasil.
Formación inicial de profesores de Matemáticas: una experiencia de intercambio internacional a partir de los estudios de aula
Authors: Ponte João Pedro da , Neves Regina da Silva Pina , Macedo Aluska Dias Ramos de , Quaresma Marisa
Published: May 2023

El estudio de clase es un proceso formativo que se ha utilizado en la formación inicial de los profesores de Matemáticas. Organizamos un intercambio entre futuros profesores de tres universidades, de Portugal y Brasil, que participaban en estudios de clase. A partir de este intercambio se buscó conocer qué aprendizajes hicieron los futuros docentes sobre aspectos fundamentales del conocimiento didáctico durante el proceso de formación, así como en los encuentros sincrónicos entre los participantes de las tres instituciones. El objetivo de este artículo es analizar estos aprendizajes de los futuros maestros y cómo vivieron este intercambio. Los datos fueron recolectados mediante el registro de las sesiones virtuales realizadas y la recolección de documentos. Los resultados muestran que el estudio de clase contribuyó al aprendizaje significativo de los futuros profesores, a saber, sobre las tareas, la planificación y la realización de una clase exploratoria, incluida la discusión colectiva. Además, los futuros profesores mostraron una comprensión de la necesidad de conocer a los estudiantes. El intercambio demostró ser una iniciativa productiva, que condujo al compromiso de los futuros maestros y reforzó su aprendizaje, especialmente en aspectos didácticos.
Conocimiento profesional de profesores que enseñan Matemáticas en la Red Municipal de Educación de São Paulo a partir de su participación en un Proyecto de Investigación basado en Estudio de Lección
Authors: Curi Edda , Martins Priscila Bernardo , Borelli Suzete de Souza
Published: May 2023

Este artículo es parte de un proyecto de investigación titulado “Discusiones Curriculares: Contribuciones de un Grupo Colaborativo para la Implementación de un Nuevo Currículo de Matemáticas y el Uso de Materiales Curriculares en la Escuela Pública Municipal de São Paulo”. Así, en este artículo, pretendemos identificar y señalar el saber profesional de los profesores que enseñan Matemáticas en el Ciclo de Alfabetización de la Red Municipal de Educación de São Paulo, en el ámbito de un Proyecto de Investigación basado en las etapas del Estudio de Lección. Para ello, adoptamos una perspectiva teórica basada en Schön (2000), Shulman (1986, 1987). El estudio tiene un carácter cualitativo, interpretativo. Se trata de profesores del Ciclo de Alfabetización que enseñan Matemáticas en el Sistema Municipal de São Paulo. Los cursos de formación se desarrollaron quincenalmente en las instalaciones de la Universidad Cruzeiro do Sul. El análisis se basó en material empírico consistente en informes, protocolos de observación, episodios de videos de entrenamiento. Los resultados de la investigación muestran que el proceso de construcción y reflexión desarrollado a partir de la metodología Lesson Study, proporciona una autorreflexión sobre el trabajo desarrollado, permitiendo evaluar lo que funcionó y traer indicios de ajuste, principalmente en relación a la planificación desarrollada de forma colaborativa.
Del Lesson Studies al Lesson Study italiano: un Proceso de Transposición Cultural
Authors: Arzarello Ferdinando , Bartolini Bussi Maria Giuseppina , Funghi Silvia , Manolino Carola , Minisola Riccardo , Ramploud Alessandro
Published: May 2023

En este artículo trazamos un recorrido que da cuenta del trabajo de Transposición del Lesson Study (LS) de la cultura oriental a la italiana a través de la perspectiva dada por el enfoque de la Transposición Cultural. En ella, el encuentro con una cultura diferente es visto como un medio capaz de suscitar en los docentes nuevas y más profundas reflexiones sobre sus propios hábitos y prácticas educativas. Llamamos al producto de este proceso el “Lesson Study Italiana” (ILS): no está establecido a priori, sino que depende de las solicitudes a los participantes que los investigadores, como formadores de docentes, eligieron implantar en él. En particular, presentamos 4 ejemplos de ILS llevados a cabo en diferentes años escolares (1, 5, 8, 9), para resaltar cómo cada equipo de LS respondió a estas solicitudes a través de sus elecciones de diseño sobre la Clase de Investigación y las reflexiones críticas de los diferentes participantes. En base a esta descripción, en las conclusiones esbozamos algunas características comunes y diferencias entre los ejemplos, con el fin de resaltar reflexiones más generales sobre las posibles formas de implementar LS en culturas distintas de las orientales.
Uso de Los Criterios de idoneidad Didáctica y la metodología Lesson Study en la formación del profesorado de matemáticas en España y Ecuador
Authors: Font Vicenç , Calle Eulalia , Breda Adriana
Published: May 2023

La literatura sobre la formación de profesores ha puesto de manifiesto la importancia de desarrollar su reflexión sobre la práctica. El objetivo de este documento es explicar el uso de la herramienta Criterios de Idoneidad Didáctica y la metodología Lesson Study en la formación del profesorado de matemáticas en España y el Ecuador. En este documento, primero, se explica brevemente, como referente teórico, estos constructos; después se explica la estructura de los ciclos formativos implementados en programas de formación del profesorado para el aprendizaje y uso de los Criterios de Idoneidad Didáctica para organizar la reflexión del profesorado sobre su práctica en España y en el Ecuador. A continuación, se explica la estructura de los ciclos formativos implementados en programas de formación del profesorado que combinan los Criterios de Idoneidad Didáctica con el Lesson Study. Por último, el documento termina con unas consideraciones sobre la evolución de este constructo.
Şeffaf Hakemlik Modeli
Authors: DEMİR Abdullah
Published: May 2023

Eskiyeni dergisi olarak 46'ncı sayımızla birlikte, Yayın Kurulu’muzun 05/02/2022 tarihli toplantısında almış olduğu karar gereğince yayımlanan tüm makalelerin hakem raporlarını da hakem isimlerinizi kapatarak makalelerle birlikte okurların incelemesine açtık. Bunun için dergi web sayfamızda “Hakem Raporları” adıyla yeni bir sayfa oluşturduk: https://dergipark.org.tr/tr/pub/eskiyeni/page/13397. Hakem raporlarının okurlara açılması, Eskiyeni dergisinde hakem sürecinin nasıl işletildiğini ortaya koyması ve göstermesi açısından önemlidir. Bilindiği üzere hakemli dergileri popüler dergilerden ayıran fark, hakem sürecinin işletilmesidir. Hakemli dergilerde genelde çift taraflı kör hakemlik, tek taraflı kör hakemlik ve açık hakemlik sistemlerinden biri kullanılmaktadır. Açık hakemlikte yazar hakemlerin kim olduğunu hakemler de yazarın kimliğini bilmektedir. Çift taraflı kör hakemlik bunun tam tersidir, yazarlar hakemleri; hakemler de yazarı öğrenememektedir. Tek taraflı kör hakemlikte ise hakemler yazarın kimliğini bilmekte; yazar ise hakemleri öğrenememektedir. Bu sistemlerden her birinin güçlü ve zayıf yönleri bulunmaktadır. Eskiyeni dergisi Yayın Kurulu; Yazarlar, hakemler, editörler ve yayın kurulu iş birliğinde yürütülen hakemli yayıncılık sürecinin yazarların ve okurların denetimine açılmasının, derginin kalitesini daha da artıracağını düşünmektedir. Bu sebeple de bu sayımızdan itibaren yayımlanan tüm makalelerin hakem raporlarını, hakem isimlerini gizleyerek yayımlama kararı almıştır. Şeffaf Hakemlik Modeli (Transparent Peer Review) olarak bilinen bu sistem yurt dışında yaygınlaşmaya başlamıştır. Reddedilen makalelerin raporları, o makalelerin şu an başka bir dergide işlemde olabileceği düşüncesi ile yayımlanmayacaktır. Yayın Kurulumuz aldığımız bu karara dair yazar, hakem ve okurlardan gelecek geri dönüşlerini dikkatle takip edecektir. İlerleyen süreçte, hakem isimlerinin de açıkça yayımlanacağı tam şeffaf hakemlik sistemine geçilmesi de değerlendirilecektir.
A STUDY ON CHALLENGES FACED BY MICRO, SMALL & MEDIUM ENTERPRISES (MSMES) IN OBTAINING CREDIT IN BIHAR
Authors: Paswan Gaurav , Jha Nagendra Kumar
Published: May 2023

Finance is a blood of an organization. It plays important role in smooth functioning of all operations of the business. Lack of the finance, adverse situation is arises in the business.
.Based on the size of their operations, the vibrant group of firms that make up the majority of the Indian economy are known Micro Small Medium Enterprises (MSME), plays a crucial role in the economic and social growth of a nation. They serve as incubators for entrepreneurship and are frequently propelled by individual creativity and invention. They also significantly contribute to the state`s GDP, manufacturing output, exports, and the creation of jobs. Despite the inherent strengths of this industry, MSMEs in Bihar are having a lot of trouble, and getting financing has become their biggest issue. This paper goes to investigate the numerous difficulties and problems experienced by MSMEs from the perspectives of both lenders and borrowers in Bihar.
Giá trị tiên lượng của khí máu động mạch ở bệnh nhân nhiễm khuẩn nặng và sốc nhiễm khuẩn
Authors: Tat Dung Nguyen
Published: May 2023

TÓM TẮT

Đặt vấn đề: Toan chuyển hóa liên quan đến mức độ nghiêm trọng của bệnh ở bệnh nhân nhiễm khuẩn nặng hoặc sốc nhiễm khuẩn. Mức độ nghiêm trọng của nhiễm toan chuyển hóa có liên quan đến kết quả lâm sàng kém. Có nhiều thang điểm và chỉ số sinh hóa để đánh giá độ nặng và tiên lượng bệnh. Chúng tôi giả thiết rằng thay đổi một số thông số trong khí máu động mạch như là yếu tố tiên lượng ở bệnh nhân bị nhiễm khuẩn nặng và sốc nhiễm khuẩn.

Đối tượng, phương pháp: Nghiên cứu quan sát mô tả tiến cứu trên 54 bệnh nhân được chẩn đoán nhiễm khuẩn nặng hoặc sốc nhiễm khuẩn theo tiêu chuẩn SSC 2016. Xét nghiệm khí máu động mạch và lactate máu được thực hiện tại ba thời điểm 0 giờ (T0), 6 giờ (T6) và 24 giờ (T24) kể từ khi chẩn đoán xác định.

Kết quả: Tỷ lệ tử vong chung là 66,7 %. Rối loạn toan kiềm cao nhất ở ba thời điểm T0, T6 và T24 là toan chuyển hóa với tỷ lệ lần lượt là 50,0%, 46,3% và 53,7%. Tại thời điểm T0 và T24, pH có giá trị tiên lượng tử vong khá với AUC - ROC lần lượt là 70,8% (KTC95%: 57,2 - 84,4) và 76,6% (KTC95%: 63,9 - 89,4). Tại thời điểm T0, với điểm cắt ≤ 13,2, độ nhạy 41,7%; độ đặc hiệu 100%, HCO3- có giá trị tiên lượng tử vong khá với AUC - ROC là 72,2% (KTC95%: 58,4 - 85,4). Tại thời điểm T0 và T24 BE có giá trị tiên lượng tử vong khá với AUC - ROC lần lượt là 71,5% (KTC95%: 58,0 - 84,9) và 70,8% (KTC95%: 56,7 - 84,8). Khoảng trống anion (AG) ở điểm cắt ≥ 19,95, độ nhạy 48,6%; độ đặc hiệu 94,1% có giá trị tiên lượng tử vong khá AUC - ROC là 75,7% (KTC95%: 62,5% - 91,4%). Chỉ số PaCO2 và PaO2/FiO2 không có ý nghĩa trong tiên lượng tử vong.

Kết luận: Một số thông số khí máu động mạch như pH, HCO3-, BE và AG có mức ý nghĩa khá trong tiên lượng tử vong ở bệnh nhân nhiễm khuẩn nặng và sốc nhiễm khuẩn. Cần có thêm những nghiên cứu đa trung tâm với số lượng dữ liệu lớn hơn để củng cố giả thiết này.
Ngộ độc thuốc tê, kinh nghiệm từ lý thuyết tới thực hành lâm sàng
Authors: Thien Nhan Tran Nguyen
Published: May 2023

TÓM TẮT

Ngộ độc thuốc tê là một tai biến mặc dù ít gặp trên lâm sàng nhưng có thể dẫn đến các biến chứng nặng do độc tính thuốc tê gây ra. Tuy nhiên, việc nhận biết các triệu chứng của ngộ độc thuốc tê trên lâm sàng thường chưa được nhân viên y tế quan tâm và đánh giá đúng mức, đặc biệt là các trường hợp xuất hiện rối loạn nhịp. Do đó, chúng tôi xin chia sẻ một trường hợp bệnh nhân nữ 52 tuổi có chỉ định phẫu thuật tiếp khẩu túi lệ xuất hiện các rối loạn nhịp nguy hiểm trong quá trình gây tê và đã được phát hiện và xử trí kịp thời.
Kết quả điều trị sẹo xấu vùng mặt sau chấn thương bằng laser fractional co2
Authors: Hong Loi Nguyen
Published: May 2023

TÓM TẮT

Mục tiêu: Đánh giá kết quả điều trị sẹo xấu vùng mặt sau chấn thương bằng Laser Fractional CO2 tại Trung Tâm Răng Hàm Mặt - Bệnh viện Trung Ương Huế

Đối tượng, phương pháp: Mô tả tiến cứu có can thiệp lâm sàng 39 bệnh nhân có sẹo xấu vùng mặt sau chấn thương có chỉ định điều trị Laser Fractional CO2 tại Trung Tâm Răng Hàm Mặt bệnh viện Trung Ương Huế từ tháng 11/2021 đến 10/2022.

Kết quả: Điểm thang đo POSAS giảm theo thời gian tại các thời điểm đánh giá 1 tháng, 2 tháng và 3 tháng sau điều trị (p < 0,001). Mức độ đau trong lúc chiếu nhẹ: 1 - 3 điểm. Tác dụng phụ đỏ da cao nhất 18,6% và kéo dài sau 3 tháng đỏ da vẫn còn 4,7%. Mức độ nhận thấy sẹo giảm theo thời gian độ III: 1 tuần: 75,6%, 3 tháng: 7,0%. Độ II: 1 tuần 23,3%, 3 tháng: 52,3%. Độ I: 1 tuần 1,2%, 3 tháng: 20,9%. Mức độ cải thiện màu sắc sẹo tăng theo thời gian. Màu sắc kém: 1 tuần 64,0%, 3 tháng 5,8%. Màu sắc khá: 1 tuần 1,2%, 3 tháng 36,0%. Kết quả cải thiện sẹo tăng theo thời gian 1 tuần 0,0%, 3 tháng 86,0% (p < 0,001). Mức độ bệnh nhân hài lòng 86%.

Kết luận: Laser Fractional CO2 là phương pháp điều trị sẹo xấu vùng mặt sau chấn thương hiệu quả, ít tác dụng phụ và mức độ bệnh nhân hài lòng cao.
A művészetterápia kulturális meghatározottsága
Authors: Gacsályi Anna
Published: May 2023

A művészetterápia fogalma egy különösen nagy területet fed le és többféle oldalról is megközelíthető, ezért sok definíciója létezik és számtalan alcsoportra osztható fel. Alapvetően a művészetterápiához tartoznak az egyes vizuális művészetekkel foglalkozó terápiák, a zeneterápia, a drámaterápia, az irodalomterápia, továbbá a tánc- és a mozgásterápia egyaránt. Japán esetében elmondható, hogy a művészetek terápiás környezetben való felhasználása sok tekintetben kötődik olyan hagyományos ágazatokhoz, mint a kadō és a kalligráfia. Jelen dolgozat elsődleges célja a művészetterápia és Japán kapcsolatának bemutatása a terápiaválasztás, a két fő énfelfogás, valamint az independens és interdependens társadalmak kulturális sajátosságai alapján. Első lépésben fogalomtörténeti oldalról lényeges megismerni a témához kapcsolódó terminológiát és annak főbb értelmezési lehetőségeit. Történelmi kontextusba helyezve fontos kitérni a pszichológia átvételének körülményeire, hiszen az újdonságnak számító tudományág jelentősen befolyásolta a japán művészetterápia alakulását. Ezzel párhuzamosan a kulturális meghatározottság szempontjából szükséges áttekinteni az én-felfogással kapcsolatos kutatásokat, valamint a japán-specifikus lélektani megfigyeléseket, mint az amae vagy az aidagara. Ezen felül Japán tekintetében érdemes még megvizsgálni a hagyományos japán művészeti irányzatok, a homokterápia és a művészetterápiák közötti összefüggéseket, mivel mind szemléletmódjukban, mind módszertani megközelítésükben sok átfedés található. Ijuin Seiichi, Nakai Hisao, Sakaki Tamotsu, Takano Naoko, Kawai Hayao, Eva Pattis Zoja, Kamei Toshihiko és Yamaguchi Toyoko munkái betekintést nyújtanak a terápia folyamatába, továbbá az egyes eseteken keresztül láthatóvá válik a képalapú nonverbális kommunikáció hatékonysága eltérő kulturális környezetben végzett terápiák során.
A közép- és kelet-európai tatárjárások történetéhez
Authors: Apatóczky Ákos Bertalan
Published: May 2023

Apatóczky Ákos Bertalan recenziója a The Routledge Handbook of the Mongols and Central-Eastern Europe című kötetről (szerk: Alexander V. Maiorov és Roman Hautala, Oxon – New York, Routledge, 2021).
Galambos Péter élete
Authors: Keller Mirella
Published: May 2023

Keller Mirella írása Galambos Péter életútjáról.
A wu 巫 („sámán”) karakter jelentésének változása a Shang-dinasztiától a Han-dinasztiáig
Authors: Olajos István
Published: May 2023

A jelen kutatás célja, hogy a wu 巫 írásjegy vizsgálatán keresztül átfogóbb képet kapjunk e vallási tevékenységet végző személy alakjáról, melyet gyakran a szibériai sámán személyével állítanak párhuzamba. Magáról a sámánról és a wuról, illetve tevékenységeik analógiájáról igen gazdag kutatási anyag áll rendelkezésre, a két fogalom rokonítása pedig gyakran képezi heves viták tárgyát a szakértők körében. A jelen írás ugyanakkor nem kíván állást foglalni ezen vélemények kusza sokasága között és a wu írásjegyet a szibériai sámán archetípustól függetlenül, a régi Kína ránk maradt írásos emlékei alapján definiálja. A wu írásjegyet tehát a sokkal ritkábban alkalmazott etimológiai vizsgálatnak vetem alá, mely során kronologikusan elemzem az írásjegy kontextuális és alaki jellemzőit, a jóslócsont-feliratoktól (jiaguwen 甲骨文) kezdve a Shuowen jiezi 說文解字 wuról szóló szócikkével bezárólag. A különböző korokból származó szövegek alapján megállapítható, hogy éles különbség mutatkozik a jóslócsont-feliratokon szereplő wu írásjegy jelentése és a Zhou-kori 周代 (i. e. 1046 – i. e. 256-ig) szövegek wuja között. Az előbbinél legtöbbször nem is egy személyt jelöl az írásjegy, vagy ha mégis, akkor egy igen alacsony státuszú illetőt. Ezzel szemben a Zhou-kori szövegek a wukat gyakran magasrangú hivatalnokokként ábrázolják, illetve a Zhou-kor előrehaladtával a wut egyre inkább a halállal, katasztrófákkal és démonokkal gazdag szövegekben említik. A két korszak szemantikai szempontból eltérő wu-értelmezését a Shuowen kapcsolja össze, amely – bár meglehetősen homályosan fogalmazva – az írásjegy eredetét a szellemeket lecsábító táncosnők alakjára vezeti vissza, ugyanakkor egyfajta ácseszközként – tehát nem személyként – is hivatkozik a wura. A jelen kutatás az írásjegy jelentésének ezen korszakonként eltérő értelmezéseit követi végig és köti össze, valamint a Shuowen etimológiai utalásaiból kiindulva fejti vissza az írásjegy kialakulásának lehetséges állomásait, hogy ezáltal adjon még átfogóbb képet a régi Kína e meglehetősen egyedi vallási tevékenységet végző személyéről, a wuról.
Antibacterial, antifungal, antifeedent and larval mortality percent of solvent extraction of mango kernel (Mangifera indica L.) cv. Totapuri
Authors: Moorthy Sambanda , M Saraswathi  , J Arunkumar  , K Perumal
Published: May 2023

Mango (Mangifera indica L.) is a seasonal fruit and is cultivated extensively in tropical and subtropical region in India and worldwide. The fruit is processed and mango pulp is extracted in fruit processing industries and kernel is unutilized as industrial waste. Hence, in the present study focused on Totapuri mango kernel cultivar was taken to utilize for bio product development. Soxhlet apparatus with different solvents was used for the crude bioactive compounds extraction from mango kernel powder. The extracted bioactive mass was evaluated for its antibacterial activity against bacterial strains such as Escherichia coli, Pseudomonas putida, Pseudomonas aeruginosa, Shigella sonnei, Klebsiella pneumonia, Xanthomonas oryzae and Staphylococcus aureuss. Further, the extracted crude bioactive compound was tested for antifungal activity against Rhizactonia solani, Curvularia lunata, Alternaria alternate and Fusarium oxysporum. The antifeedent and larval mortality of Spodoptera litura and Helicoverpa armigera activity was studied using the bioactive compound extract. The Methanol Mango Kernel extract (MeOH MK) recorded growth inhibition zone for all the bacteria tested ranging from 21±0.31 to 24±1.55 mm. At 5 % MeOH MK crude extract concentration, the fungal mycelia growth of R. solani was inhibited by 92.90 ± 0.31 %. The highest percent of antifeedent activity was observed in 5% MeOH MK extract recorded as 77.37 %± 0.75 for S.litura and 55. 1.06 for H.armigera. The crude extract of MeOH MK at 5 % concentration recorded 17.8 %± 2.2 mortality rate for S. leutira larva and 100 % mortality rate for H. armigra. The MeOH MK extract was effective as antibacterial, antifungal, antifeedent and larval mortality.
Isolation of a new Aspergillus iranicus strain from the soil of southwestern Algeria exhibiting potential palm date-cellulose degrading activity
Authors: Makhloufi Souad , Makhloufi Ahmed , Chebloune Yahia
Published: May 2023

Microorganisms with biotechnological properties are needed for transformation or degradation of biological products. Here we isolated a new Aspergillus strain (MS-34) from the soil of southwestern Algeria and found that it is related to Aspergillus iranicus. The MS-34 was examined for possible biotechnological properties and we found it to be highly efficacious at degrading palm date cellulose following fermentation. Pretreatment fermentation of palm in 50 % generated the highest (197.84 mg/L) carbohydrate concentration. Pretreatment with 20% KOH produced a maximum 112.97 IU/ml and 47.62 IU/ml for endoglucanase and exoglucanase activities respectively. Besides, glucose and proteins concentration in batch fermentations with 1% CMC medium fluctuated between 86.41 mg/l to 108.85 mg/l and the protein level was 0.713- 0.991 mg/ml. There were significant temperature and pH effects on the enzymatic activity and the optimal temperature conditions were found to be 50-60°C and pH 4.0. Since palm dates are one of the massive agricultural products of the Southeastern and Southwestern Algeria, use of this strain for transformation of palm tree waste will be an advanced biotechnology tool that will contribute to significantly reduce pollution linked to waste incineration. In addition, resulting fermentation products may be used as sources of energy.
183 GHz Water Megamasers in Active Galactic Nuclei: A New Accretion Disk Tracer
Authors: Pesce Dominic W. , Braatz James A. , Henkel Christian , Humphreys Elizabeth M. L. , Impellizzeri C. M. Violette , Kuo Cheng-Yu
Published: May 2023

We present the results of an Atacama Large Millimeter/submillimeter Array survey to identify 183 GHz H2O maser emission from active galactic nuclei (AGNs) already known to host 22 GHz megamaser systems. Out of 20 sources observed, we detect significant 183 GHz maser emission from 13; this survey thus increases the number of AGN known to host (sub)millimeter megamasers by a factor of 5. We find that the 183 GHz emission is systematically fainter than the 22 GHz emission from the same targets, with typical flux densities being roughly an order of magnitude lower at 183 GHz than at 22 GHz. However, the isotropic luminosities of the detected 183 GHz sources are comparable to their 22 GHz values. For two of our sources—ESO 269-G012 and the Circinus galaxy—we detect rich 183 GHz spectral structure containing multiple line complexes. The 183 GHz spectrum of ESO 269-G012 exhibits the triple-peaked structure characteristic of an edge-on AGN disk system. The Circinus galaxy contains the strongest 183 GHz emission detected in our sample, peaking at a flux density of nearly 5 Jy. The high signal-to-noise ratios achieved by these strong lines enable a coarse mapping of the 183 GHz maser system, in which the masers appear to be distributed similarly to those seen in VLBI maps of the 22 GHz system in the same galaxy and may be tracing the circumnuclear accretion disk at larger orbital radii than the 22 GHz masers. This newly identified population of AGN disk megamasers presents a motivation for developing VLBI capabilities at 183 GHz.
Constraints on the Epoch of Reionization with Roman Space Telescope and the Void Probability Function of Lyα Emitters
Authors: Perez Lucia A. , Malhotra Sangeeta , Rhoads James E. , Wold Isak G. B.
Published: May 2023

We use large simulations of Lyα emitters with different fractions of ionized intergalactic medium to quantify the clustering of Lyα emitters as measured by the void probability function (VPF), and how it evolves under different ionization scenarios. We quantify how well we might be able to distinguish between these scenarios with a deep spectroscopic survey using the future Nancy Grace Roman Space Telescope. Because Roman will be able to carry out blind spectroscopic surveys of Lyα emitters continuously between 7 < z < 12 to sensitivities of at least 10−17 erg s−1 over a wide field of view, it can measure the epoch of reionization as well as the pace of ionization of the intergalactic medium (IGM). We compare deep Roman surveys covering roughly 1, 4, and 16 deg2, and quantify what constraints on reionization the VPF may find for these surveys. A survey of 1 deg2 would distinguish between very late reionization and early reionization to 3σ near z = 7.7 with the VPF. The VPF of a 4 deg2 survey can distinguish between slow versus fast, as well as early versus late, reionization at >3σ–4σ at several redshifts between 7 < z < 9. However, a survey of 13–16 deg2 would allow the VPF to give several robust constraints (>5–8σ) across the epoch of reionization, and would yield a detailed history of the reionization of the IGM and its effect on Lyα emitter clustering.
Lunar Laser Ranging Retroreflectors: Velocity Aberration and Diffraction Pattern
Authors: Williams James G. , Porcelli Luca , Dell’Agnello Simone , Mauro Lorenza , Muccino Marco , Currie Douglas G. , Wellnitz Dennis , Wu Chensheng , Boggs Dale H. , Johnson Nathan H.
Published: May 2023

The Lunar Laser Ranging (LLR) retroreflector arrays have been on the Moon for half a century. During that time, the laser range uncertainty has improved by a factor of 100. Consequently, the science results have also improved by orders of magnitude. New retroreflectors are scheduled to go to the Moon on Commercial Lander Payload Services missions and the Lunar Geophysical Network mission. The new retroreflectors are single 10 cm corner cube retroreflectors that will not spread the laser pulse during reflection like the existing arrays do. Due to the orbital and Earth rotational speeds, there is a velocity aberration of 0.″8–1.″5 for existing stations. Larger corner cubes require attention to ensure that the spread of possible velocity aberration displacements is optimally contained within the diffraction pattern. The diffraction pattern can be changed by making one or more of the rear dihedral angles slightly different from 90°. Improvements in the equipment at the LLR stations and improvements in the data analysis software are also desirable. Future possibilities are described.
Spinal Stenosis with Sacral Osseous Deformity Mimicking Chronic Inflammatory Demyelinating Polyneuropathy
Authors: Stolevski Vlado , Bosnjak Roman , Ilievski Boro , Dimovski Aleksandar
Published: May 2023

BACKGROUND: Differential diagnoses of neurosurgical spinal disorders and polyneuropathies have been recognized to cause clinical perplexity, occasionally misdiagnosing chronic inflammatory demyelinating polyneuropathy (CIDP). When nerve conduction studies and cerebrospinal fluid (CSF) analyses reinforce a certain clinical presentation, the importance of imaging studies, conservative treatment response, and interdisciplinary clinical approach should be highly emphasized.

CASE PRESENTATION: We report a 51-year-old patient who presented with a 16-week history of neurogenic claudication and right-sided lower extremity monoparesis, with low back pain syndrome dating from 10 years ago. He was initially evaluated by a neurologist under the suspicion of CIDP, supported by nerve conduction studies and CSF analyses, without any subjective or objective improvements after systemic corticosteroid therapy. After performing magnetic resonance imaging (MRI) of the lumbosacral spine, he was referred to a neurosurgeon. Neurological examination revealed features of lower motor neuron lesion, consistent with the MRI findings of L4-L5 and L5-S1 stenosis with right-sided S1 vertebra osseous deformity, without any radiographic evidence of CIDP. The patient underwent surgery and improvements were noted early in the post-operative recovery phase and continuously throughout the regular monthly follow-ups, without any clinical features of CIDP. Histopathology results confirm sacral osseous deformity. No evidence of CIDP, osseous deformity residue, or recurrence was evident on the post-operative MRI control performed 11-month post-surgery.

CONCLUSIONS: Degenerative spinal stenosis compromising spinal canal dimensions can mimic CIDP due to sharing multiple clinical similarities. That scenario is especially highlighted when age-related spinal degenerative disease is unexpected and seldom aggravated by spinal osseous lesions. Avoiding misdiagnosis and providing adequate treatment can pose a serious challenge for neurosurgeons and neurologists, demonstrating the importance of an interdisciplinary approach toward diverse spinal disorders.
Coronavirus Disease-19: Correlation between Knowledge and Preventive Behavior by Medical Students after One Year of Pandemic and Factors that Affect Knowledge
Authors: Salim Chandra Pranata , Sinaga Bintang Yinke Magdalena
Published: May 2023

BACKGROUND: The COVID-19 pandemic, which started in December 2019, is still continuing to date (November 2021), and nobody knows how long it will remain. During this time, the world remains vigilant against the pandemic, causing new problems in various fields of life. At the same time, the public continues getting latest information about COVID-19. One and a half year is not a short time to continuously carry out COVID-19 preventive behavior, which in turn causes relaxation of COVID-19 preventive behavior.
AIM: This study aims to determine the correlation between knowledge and COVID-19 preventive behavior after one year of pandemic among medical students and to find out factors that affect knowledge about COVID-19.
METHODS: This is a descriptive-analytic cross-sectional study with 261 respondents collected from students of the Faculty of Medicine, Universitas Sumatera Utara. Respondents' data was collected using an online questionnaire which had been tested for its validity and reliability. Distribution of sample size used proportionate stratified random sampling and simple random sampling. Data will be analyzed using chi-square.
RESULTS: Of the 261 respondents analyzed, 247 respondents (94.7%) had good level of knowledge, 222 respondents (85.1%) had good level of preventive behavior, and the factors that influenced knowledge were the year of admission (p-value: 0.028) and family member with past confirmed case of COVID-19 (p-value: 0.011). The knowledge and preventive behavior relationship analysis showed p-value: 0.009 (PR = 4.864 [95% CI 1.587-14.909]).
CONCLUSION: Even though the pandemic has lasted for more than 1year, medical students with good level of knowledge still carry out good preventive behavior showing a meaningful relationship between knowledge and preventive behavior. Level of knowledge is influenced by the year of admission and family member with past confirmed case of COVID-19.
Jewels on the go: exotic buprestids around the world (Coleoptera, Buprestidae)
Authors: Ruzzier Enrico , Haack Robert A. , Curletti Gianfranco , Roques Alain , Volkovitsh Mark G. , Battisti Andrea
Published: May 2023

Buprestidae (Coleoptera: Buprestoidea) is one of the three wood-borer beetle groups of major phytosanitary interest worldwide, together with Cerambycidae and Scolytinae (Curculionidae). As in other beetle families, some buprestid species have been unintentionally or intentionally introduced around the world, in some cases causing significant environmental and economic damage in the invaded territories. Despite the phytosanitary relevance of the Buprestidae, information regarding the identity of exotic buprestids, their biogeographic areas of origin, introduction pathways, and larval host plants, have remained scattered in the literature. Our objective was to summarize much of the existing knowledge on these topics in the present paper. Our analysis resulted in a list of 115 exotic buprestids worldwide, representing introductions both within and between biogeographic realms and corresponding to less than 1% of the known buprestid species worldwide. Invasiveness does not seem to be linked to their larval host plant preferences, as introduced species utilize 158 plant genera in 70 plant families and are equally represented in all feeding guilds (monophagous, oligophagous, and polyphagous). As trade of plants or plant parts can serve as a pathway for future introductions, the information reported in this review can help in pest risk assessment.
Awareness, detection and management of new and emerging tree pests and pathogens in Europe: stakeholders’ perspectives
Authors: Green Samantha , Dehnen-Schmutz Katharina , Drakulic Jassy , Eschen René , Orazio Christophe , Douma Jacob C. , Lundén Karl , Colombari Fernanda , Jactel Hervé
Published: May 2023

Emerging and invasive tree pests and pathogens in Europe are increasing in number and range, having impacts on biodiversity, forest services, ecosystems and human well-being. Stakeholders involved in tree and forest management contribute to the detection and management of new and emerging tree pests and pathogens (PnPs). We surveyed different groups of stakeholders in European countries. The stakeholders were mainly researchers, tree health surveyors and forest managers, as well as forest owners, nurseries, policy-makers, advisors, forestry authorities, NGOs and civil society. We investigated which tools they used to detect and manage PnPs, surveyed their current PnP awareness and knowledge and collated the new and emerging PnP species of concern to them. The 237 respondents were based in 15 European countries, with the majority from the United Kingdom, France and the Czech Republic. There was a strong participation of respondents with a work focus on research and surveying, whereas timber traders and plant importers were less represented. Respondents were surveyed on 18 new, emerging PnPs in Europe and listed an additional 37 pest species and 21 pathogen species as potential future threats. We found that species on EPPO’s list of ‘priority pests’ were better known than those not listed. Stakeholders working in urban environments were more aware of PnPs compared to those working in rural areas. Stakeholders’ awareness of PnPs was not related to the number of new, emerging PnP species present in a country.

Stakeholders want access to more detection and management tools, including long-term citizen-science monitoring, maps showing spread and range of new PnPs, pest identification smartphone apps, hand-held detection devices, drone monitoring and eDNA metabarcoding. To help facilitate better forest health across Europe, they called for mixed forest development, reduced nursery stock movement, biosecurity and data sharing amongst organisations. These results indicate that stakeholder knowledge of a few key PnP may be good, but given that the large diversity of threats is so large and future risks unknown, we conclude that multiple and varied methods for generic detection, mitigation and management methods, many in development, are needed in the hands of stakeholders surveying and managing trees and woodlands in Europe.
Myrtus communis in Europe threatened by the pandemic and South African strains of the myrtle rust pathogen Austropuccinia psidii (Sphaerophragmiaceae, Pucciniales)
Authors: Paap Trudy , Santini Alberto , Rodas Carlos A. , Granados Ginna M. , Pecori Francesco , Wingfield Michael J.
Published: May 2023

Austropuccinia psidii, the causal agent of myrtle rust, has emerged as a significant threat to Myrtaceae in planted and natural woody ecosystems. The first detection of A. puccinia in South Africa was from severely infected ornamental Myrtus communis. This raised concern that M. communis, the sole Myrtaceae species native to Europe and an important component of vegetation in Mediterranean regions, could be threatened by the rust. In light of the potential threat to this unique species, seed was collected from 12 Italian provenances of M. communis, including mainland and island (Sardinia and Sicily) populations. We assessed the susceptibility of these provenances to both the pandemic and South African strains of A. psidii. In Colombia, where the pandemic strain of A. psidii is native, seedlings rapidly became infected by natural inoculum. In South Africa, a preliminary screening of seedlings by artificial inoculation with a single-uredinium isolate produced high levels of disease. Finally, plants of each of the 12 provenances were planted and monitored in Florence, Italy. To date, these showed no signs of disease, but will continue to be monitored. This study highlights the significant threat that both the pandemic and South African strains of A. puccinia pose to M. communis in Europe.