bluuebunny/crossref_metadata_2025 huggingface dataset:
HUBUNGAN KUALITAS TIDUR DAN AKTIVITAS FISIK DENGAN KADAR GULA DARAH PASIEN DIABETES MELLITUS TIPE II DI POLIKLINIK PENYAKIT DALAM RSUD SULTAN IMANUDDIN PANGKALAN BUN
Authors: Hamid Resky Apriulendari.A. , Ningtyas Ni Wayan Rahayu , Syahleman Rukmini
Published: November 2021

Latar belakang : Diabetes merupakan penyakit dimana kondisi kadar gula di dalam darah melebihi nilai normal. Perubahan jadwal tidur membuat kualitas tidur tidak optimal. Semakin tinggi melakukan aktivitas semakin rendah kadar gula darah.Tujuan : Untuk mengetahui hubungan kualitas tidur dan aktivitas fisik dengan kadar gula darah pasien diabetes mellitus tipe II di Poliklinik Penyakit Dalam RSUD Sultan Imanuddin Pangkalan BunMetode Penelitian : Kuantitatif dengan jenis penelitian deskriptif korelasi, desain cross sectional. Sampel 101 orang, teknik purposive sampling, uji analisis korelasi pearson product moment.Hasil dan Analisis: Jenis kelamin perempuan 59 orang, usia 50-59 tahun 42 orang, pekerjaan swasta 48 orang, pendidikan SD 50 orang, kualitas tidur buruk 98 orang, aktivitas fisik ringan 50 orang, kadar gula darah tinggi 71 orang. Hasil analisis menunjukkan terdapat hubungan kualitas tidur dengan kadar gula darah nilai p value = 0,027, terdapat hubungan aktivitas fisik dengan kadar gula darah nilai p value = 0,049.Kesimpulan : Sebagian besar jenis kelamin perempuan, hampir separuh responden usia 50-59 tahun, hampir separuh responden pekerjaan swasta, hampir separuh responden pendidikan SD, hampir semuanya kualitas tidur buruk, hampir setengahnya aktivitas fisik ringan, sebagian besar responden kadar gula darah tinggi. Terdapat hubungan antara kualitas tidur dengan kadar gula darah pasien diabetes mellitus tipe II di Poliklinik Penyakit Dalam RSUD Sultan Imanuddin Pangkalan Bun. Terdapat hubungan antara aktivitas fisik dengan kadar gula darah pasien diabetes mellitus tipe II di Poliklinik Penyakit Dalam RSUD Sultan Imanuddin Pangkalan Bun. Kata Kunci : Kualitas Tidur, Aktivitas Fisik, Diabetes Mellitus
PIJAT BAYI
Authors: Isnina Isnina
Published: November 2021

Periode penting dalam tumbuh kembang anak adalah masa balita karena pada masa ini pertumbuhan dasar akan mempengaruhi dan menentukan pertumbuhan dan perkembangan selanjutnya. Agar anak dapat mencapai pertumbuhan yang optimal, maka diperlukan suatu bentuk perawatan yang lebih intensif diantaranya berupa sentuhan dan stimulasi yang terus-menerus. Salah satunya adalah dengan pemberian massage. Massage merupakan upaya pemenuhan kebutuhan anak baik secara fisik, kasih sayang serta stimulasi mental. Tanpa disadari ketika memandikan bayi, mengeringkan tubuhnya dengan menggosok punggungnya, atau bermain-main dengan cara memijat kakinya, sebenarnya banyak rangsangan yang dilakukan padanya. Dari sini akan diketahui pijatan mana yang menyenangkan bagi bayi dan mana yang tidak disukainya. Lama-lama kita akan menjadi lebih terampil dan percaya diri dalam mengurus bayi.Sasaran dari kegiatan pengabdian masyarakat ini adalah ibu-ibu kader posyandu balita di desa Pangkalan Tiga. Metode dalam kegiatan pengabdian ini yaitu menggunakan metode ceramah dalam penyampaian materi. Hasil dari pelaksanaan pengabdian kepada masyarakat Pijat Bayi pada ibu-ibu kader di desa Pangkalan Tiga ini dapat dilihat dari indikator ketercapaian tujuan, yaitu setelah mendapatkan penyuluhan pijat bayi masyarakat memahami manfaat dan teknik pijat bayi yang telah diajarkan. Ibu-ibu kader sangat antusias dan dapat melakukan penijatan bayi guna meningkatkan kesehatan bayinya. Kata kunci      : Pijat Bayi
SENAM NIFAS BERSAMA DALAM PROSES INVOLUSI UTERI PADA IBU POST PARTUM DI BPS IDA SISWIASTUTIK KOTA PANGKALAN BUN
Authors: Oktarina Jenny
Published: November 2021

Masa nifas (peurperium) dimulai setelah kelahiran plasenta dan berakhir ketika alat-alat kandungan kembali seperti keadaan sebelum hamil. Masa nifas berlangsung selama kira-kira 6 minggu. Proses pemulihan kesehatan pada masa nifas merupakan hal yang sangat penting bagi ibu setelah melahirkan, dimana ligamen-ligamen dan diafragma pelvis serta fasia yang meregang sewaktu kehamilan dan persalinan, setelah janin lahir berangsur-angsur kembali seperti sedia kala. Tidak jarang ligamen menjadi kendor yang mengakibatkan uterus jatuh kebelakang, tidak jarang pula wanita mengeluh kandungannya turun setelah melahirkan oleh karena ligamen, fasia, jaringan penunjang alat genetalia menjadi agak kendor. Untuk memulihkan kembali jaringan jaringan penunjang alat genitalia tersebut, juga otot-otot dinding perut dan dasar panggul dianjurkan untuk melakukan latihan-latihan fisioterapi  tertentu  yang dapat dilakukan pada dua hari post partum.Khalayak sasaran dari pengabdian masyarakat ini ialah ibu-ibu post partum yang melakukan kunjungan di BPS Ida Siswiastutik. Untuk memecahkan permasalahan yang dihadapi dalam kegiatan ini, maka dipilih beberapa metode pemecahan sebagai berikut: 1) Metode ceramah dan tanya jawab digunakan saat penyampaian materi senam nifas. 2) Metode demonstrasi dan latihan digunakan pada saat mempraktikkan senam nifas.Kegiatan dilaksanakan di BPS Ida Siswiastutik karena ibu post partum di BPS tersebut belum mengetahui tentang senam nifas dan tidak mengetahui cara melakukan senam nifas. Waktu pelaksanaan kegiatan selama 90 menit yang meliputi apersepsi tentang senam nifas, penyampaian pendidikan kesehatan tentang senam nifas, tanya jawab, demonstrasi senam nifas, redemonstrasi senam nifas dan evaluasi pendidikan kesehatan yang telah disampaikan kepada responden post partum.Kata kunci      : Tingkat Kecemasan, KIE, Menopause
The Effects of Consumers’ Buying Behavior on E-Commerce Pricing in the Highly Developed Emerging Market: The Case of Singapore
Authors: Moerth-Teo Jia Yun , Bobek Vito , Horvat Tatjana , Milost Franko
Published: November 2021

This paper is focused on Singapore and its e-commerce markets. It contains the theoretical part and the conduct of an empirical study where the results are studied. This study is further extended as an investigation of the effects of consumers’ buying behavior on the e-commerce market in the case of Singapore, a highly developed emerging market. This research aims to gain a detailed insight and better understand Singaporeans buying behavior and how it may or may not affect the e-commerce market.
A LÍNGUA REFÚGIO
Authors: Indursky Alexei Conte
Published: November 2021

Este artigo propõe-se pensar a especificidade da clínica com refugiados com base no uso da língua de acolhimento por parte do analisando e seus destinos na transferência. Mais especificamente, visa-se a pensar como o encontro com língua do analista, pelo enlace transferencial, pode engajar o sujeito em um movimento de ida e vinda entre sua língua de origem e a de acolhimento, que promova a desintoxicação dos conteúdos traumáticos operada pela sua transcrição em outra espacialidade psíquica; hipótese clínica que nomeia este artigo. Para tanto, propõe-se a revisão teórica do termo “tradução” na bibliografia psicanalítica, notadamente a partir da obra inédita no Brasil de Janine Altounian, atentando ao “papel tradutor” que a transferência opera ante episódios traumáticos não metabolizados pelo psiquismo. A seguir, uma vinheta clínica é utilizada para ilustrar os debates teóricos suscitados.

Palavras-Chave: Refúgio, língua, transferência, tradução, trauma.
Soil Biodiversity and Root Pathogens in Agroecosystems
Authors: del Pilar Rodríguez Guzmán María
Published: November 2021

Soil ecosystem is a living and dynamic environment, habitat of thousands of microbial species, animal organisms and plant roots, integrated all of them in the food webs, and performing vital functions like organic matter decomposition and nutrient cycling; soil is also where plant roots productivity represent the main and first trophic level (producers), the beginning of the soil food web and of thousands of biological interactions. Agroecosystems are modified ecosystems by man in which plant, animal and microorganisms biodiversity has been altered, and sometimes decreased to a minimum number of species. Plant diseases, including root diseases caused by soil-borne plant pathogens are important threats to crop yield and they causes relevant economic losses. Soil-borne plant pathogens and the diseases they produce can cause huge losses and even social and environmental changes, for instance the Irish famine caused by Phytophthora infestans (1845–1853), or the harmful ecological alterations in the jarrah forests of Western Australia affected by Phytophthora cinnamomi in the last 100 years. How can a root pathogen species increase its populations densities at epidemic levels? In wild ecosystems usually we expect the soil biodiversity (microbiome, nematodes, mycorrhiza, protozoa, worms, etc.) through the trophic webs and different interactions between soil species, are going to regulate each other and the pathogens populations, avoiding disease outbreaks. In agroecosystems where plant diseases and epidemics are frequent and destructive, soil-borne plant pathogens has been managed applying different strategies: chemical, cultural, biological agents and others; however so far, there is not enough knowledge about how important is soil biodiversity, mainly microbiome diversity and soil food webs structure and function in the management of root pathogens, in root and plant health, in healthy food production, and maybe more relevant in the conservation of soil as a natural resource and derived from it, the ecosystem services important for life in our planet.
Narcolepsy Treatment: Present and Future
Authors: José Ortega-Albás Juan , López García Raquel , Martínez Martínez Alfonso , Carratalá Monfort Sonia , Antonio Royo Prats Juan , Albiol Varela Laura , Ortega Gabás Patricia
Published: November 2021

Narcolepsy is a chronic, disabling sleep disorder with a significant diagnostic delay. Nowadays, treatment is focused on managing symptoms that impacts patient’s life, such as at workplace, social events or even at school, but not aimed cure the disease. However, we have pharmacological treatments that effectively help control the main symptoms (excessive daytime sleepiness, cataplexy, fragmentation of nocturnal sleep, sleep paralysis and hypnagogic and hypnopompic hallucinations). On the other hand, pharmacological treatment must be individualised as there are great variations in severity, order of appearance symptoms and development of the disease. We intend to expose the different symptomatic treatments recommended by clinical guidelines and the clinical management from a practical point of view. Future treatments include therapies based on the replacement of hypocretin or the administration of agonist receptors. Other techniques such as hypothalamic stem cell transplantation, gene replacement therapy or immunotherapy are also being investigated.
Potential Utility of Oral Mucosal Capillaroscopy as an Indicator of Microvascular Damage in Behçet Disease: A Preliminary Study
Authors: Demirbaş Abdullah , Elmas Ömer Faruk , Ulutaş Demirbaş Gözde , Atasoy Mustafa , Türsen Ümit , Lotti Torello
Published: November 2021

Introduction: Behçet disease (BD) is an auto-inflammatory condition characterized by multisystemic vasculitis. Oral mucosal capillaroscopy is an easy-to-use, repeatable, non-invasive method for evaluating mucosal microvasculature, contributing to the differential diagnosis and prognosis of various acute and chronic inflammatory diseases.

Objectives: This study aims to characterize and describe the oral labial mucosal capillary findings in patients with BD using handheld dermatoscopy and to investigate the relationship between the capillary findings and the severity of the disease.

Methods: This cross-sectional study included patients with BD and healthy subjects. Capillaroscopic examination of the oral labial mucosa in each subject was performed by a handheld dermatoscope using polarized light.   The clinical severity of BD was evaluated using Krause's Clinical Severity Scoring for BD.

Results: Sixty patients with BD and 60 healthy subjects were enrolled in the study. The frequencies of irregular capillaries, microhemorrhages, glomerular vessels, megacapillaries, and tortuous vessels were statistically significantly higher in the patient group when compared to the healthy individuals. In addition, a correlation was detected between the oral mucosal capillaroscopic findings and disease duration, severity, and vascular complications.

Conclusions: Our study is the first to explore the potential role of oral mucosal capillaroscopic examination in patients with BD. Data obtained from this study indicated that oral mucosal capillaroscopy may be a useful tool to demonstrate microvascular damage in patients with BD.
USO DE MEDICAMENTOS POTENCIALMENTE INAPROPRIADOS PARA IDOSOS ATENDIDOS EM UMA ESTRATÉGIA SAÚDE DA FAMÍLIA
Authors: Pinheiro Andressa Letierre Dornelles , Pereira Patricia Figueroa , Zambra Andressa Leal , Deuschle Viviane Cecília Kessler Nunes , Bortolotto Josiane Woutheres , Bonfanti-Azzolin Gabriela
Published: November 2021

Objetivo: Analisar o uso prescrito de medicamentos potencialmente inapropriados (MPI) para idosos em uma Estratégia Saúde da Família (ESF).Métodos: Esse é um estudo transversal e quantitativo, no qual os dados foram coletados através de um questionário estruturado. Foram incluídos indivíduos de ambos os sexos, de 60 a 89 anos que utilizavam no mínimo um tipo de medicamento e pertenciam à ESF objeto de estudo.Resultados: Dos 40 idosos participantes, 52,5% utilizava mais de 5 medicamentos e 92,5% utilizavam ao menos um MPI prescrito. Dentre os usuários de MPI, 45,9% consideram sua saúde muito boa/boa, 56,7% praticavam polifarmácia, e auto relataram reações adversas como fraqueza (21,6%), tontura (21,6%) e dor de estômago (10,8%). Ainda, dos 29 MPI identificados, 46,5% fazem parte da REMUME, sendo os mais utilizados hidroclorotiazida (70,9%), omeprazol (48,3%) e clonazepam (19,3%).Considerações Finais: O uso de MPI por idosos atendidos pelo sistema público de saúde é elevado e está relacionado à prática da polifarmácia e ocorrência de reações adversas. Além disso, mostra-se necessário a disponibilidade de medicamentos adequados à população idosa no saúde pública municipal, além da orientação dos profissionais prescritores e dispensadores de medicamentos para garantir uma farmacoterapia adequada a essa população.
Diálogos entre Dança na Escola e dança no TikTok: Propostas no ensino remoto
Authors: Allemand Débora Souto , Bonfim Larissa
Published: November 2021

Baseado nas experiências de inserção do componente curricular Dança nos Colégios de Aplicação da UFPE e da UFRGS no ano de 2020, o trabalho compartilha proposições de atividades remotas de criação em dança a partir de ferramentas do TikTok. A pesquisa reflete sobre os pressupostos teórico-metodológicos dessas propostas em busca de uma práxis dialógica, tendo o recurso Duetos do aplicativo como uma possível metáfora para a construção do conhecimento em Dança na Escola. Observa-se que esta pesquisa artístico-pedagógica foi um interessante meio de compreensão das referências de dança da juventude, o que possibilitou a investigação em Dança, por docentes e estudantes, de forma horizontal, criativa e contextualizada.
Aplicativos para o ensino remoto de teatro: Avatar, deepfake, padlet e outras experimentações
Authors: D'Avila Junior Francisco de Paulo
Published: November 2021

O presente texto versa sobre práticas de um professor de teatro, realizadas em Escolas Estaduais de Minas Gerais, em regime emergencial de ensino remoto, imposto pela crise sanitária do Covid-19. Será apresentada uma breve discussão sobre o uso de tecnologias aplicadas à educação, assim como reflexões sobre o papel do teatro na escola e sobre o que pode o teatro neste contexto de aulas remotas. O relato acompanha uma reflexão crítica dos processos, e demonstrações através de imagens, textos e vídeos. Os aplicativos se tornaram uma possibilidade real e foram utilizados em diversas práticas, como algo capaz de integrar aspectos da própria experiência teatral.
ÉPICO: Processo criativo em pandemia sobre o teatro épico de Brecht
Authors: Fávero Mateus , Atencio David
Published: November 2021

Este artigo pretende socializar os modos de produção do processo de pesquisa e criação de ÉPICO, da companhia Tercer Abstracto (Chile/Brasil), a fim de responder as perguntas:  Como trabalhar as propostas políticas e artísticas de Bertolt Brecht em tempos de pandemia? Como elaborar, a partir do teatro épico, um experimento cênico desenhado para o ambiente virtual? A partir da análise de documentos, das elaborações de pensamento explícito de Tercer Abstracto e do resultado final da peça ÉPICO, pretende-se demonstrar como a pandemia e o tecnovívio afetaram o processo de pesquisa, conduzindo-o para uma experimentação no ambiente virtual acerca das condições de trabalho e organização coletiva em períodos pandêmicos.
Amantes em confinamento: A videochamada como dispositivo cênico
Authors: Romano Olívia Camboim , Brazil Marcelo Alves
Published: November 2021

Neste artigo, os autores apresentam uma reflexão sobre o processo de criação do vídeo teatral Amantes em confinamento, relativa, especialmente, ao texto, à atuação e à sonoplastia. O trabalho foi realizado de forma remota, entre setembro de 2020 e janeiro de 2021, no âmbito da extensão universitária da Universidade Federal de Sergipe. A construção foi colaborativa e contou com docentes e discentes dos cursos de Teatro e de Cinema e Audiovisual. A videochamada foi tomada como dispositivo cênico e não somente como ferramenta de comunicação, ensaios e captação de imagens. O trabalho nos mostrou que é possível criar colaborativamente, ensaiar e atuar por meios remotos, e nos motivou a seguir investigando esse formato.
Artes da cena com crianças e professoras em tempos pandêmicos: O que pode nos ensinar uma cadela cega?
Authors: Ferreira Taís
Published: November 2021

Este é um relato reflexivo-analítico sobre um projeto de extensão universitária em pedagogia das artes cênicas com crianças pequenas, suas professoras e famílias, desenvolvido ao longo da pandemia. O tema indutor foram as peripécias de uma cadela real com múltiplas deficiências, portanto, as videoperformances criadas articulam material documental às artes da cena. Os podcasts e o material didático escrito veiculam proposições práticas e reflexões sobre pedagogias das artes cênicas com crianças. Os produtos gerados e seu alcance evidenciam a relevância da extensão universitária em artes e educação, bem como os sentidos produzidos pelo projeto na formação inicial das licenciandas e na formação continuada de pedagogas.
Estratégias para sair de si ou de que vida se trata? : Aula online de atuação em tempo de pandemia
Authors: Lima Tatiana Motta , Miguez Marcelo , Carcano Valentina Ramos , Reis Whiverson
Published: November 2021

O artigo analisa práticas pedagógicas realizadas na universidade, em aulas de atuação cênica, em ambiente remoto, no período pandêmico. Os estudantes foram convidados a refletir sobre os regimes atencionais mais operantes na sociedade contemporânea, e a investigar, em suas casas e espaços cotidianos, um regime de percepção outro, estruturado em torno do silêncio, da paragem, do alargamento do tempo e da saída de si mesmo na direção dos outros. As experiências criativas individuais gestadas nesse novo ambiente atencional foram analisadas coletivamente, transformando a sala de aula em um laboratório onde a arte se apresentava como um lugar propício à imaginação de mundos outros, menos violentos, individualistas e antropocentrados.
Laboratórios de criação no meio do caos pandêmico: Visualidades e os figurinos da personagem negra
Authors: Costa Carla Aparecida
Published: November 2021

A espera pelo acontecimento, a busca pela criação com ética e com respeito à história e trajetória da personagem negra. Esse texto traz a experiência vivida em sala de aula e as expectativas de como criar figurinos para e sobre temáticas negras. Apresentamos aqui fatos ocasionados pela pandemia e a superação do corpo discente que em meio ao caos buscou forças para criar e projetar figurinos para a personagem negra que por muitos séculos foi invisibilizada nos palcos dos teatros brasileiros. O relato apresentado faz parte da tese de doutorado que está em fase de pesquisa.
Diversity, Growth, and Understanding: School Responses to Immigration in Rural New Brunswick
Authors: Hamm Lyle D. , Bragdon Marc , McLoughlin John , Massfeller Helen , Hamm Lauren A.
Published: November 2021

The province of New Brunswick is growing its population through immigration and retention strategies of newcomers to grow and stabilize its economy. Many communities, traditionally unaccustomed to such growth, are now experiencing a rapid shift in their ethnocultural populations. This report is based on a case study research conducted in three rural New Brunswick schools in three closely connected communities. Each school is confronting their own issues with the shift in their student demographics, but all share common strengths and challenges. The researchers identified four main intersecting themes, each connected to a sub-theme. They found that: 1). Newcomer students are striving hard to learn and live in an English culture; 2). Newcomer students are working to belong in their school through finding Canadian-born friends and allies; 3). Educators and newcomer students are mindful that deficit thinking hinders language and verbal communication; and 4). Stereotypical perceptions about new immigrants taking jobs away from New Brunswickers are pervasive and consistent in the schools and communities that were studied. As more newcomers arrive in the province, the researchers advocate that educators and school leaders need more knowledge and support for working with newcomer students and families. Further, deeper conversations about stereotyping and racism will need to occur to effectively eradicate the negative perceptions about immigrants and immigration in the province.
Perineal trauma in nulliparous women and its associated factors
Authors: Santos Rebeca Vieira dos , Pereira Alianny Raphaely Rodrigues , Lima Cláudia Regina Oliveira de Paiva , Dantas Diego de Sousa , Ferreira Caroline Wanderley Souto
Published: November 2021

Introduction: Perineal trauma is an important complication for women after giving birth. Objective: To evaluate the prevalence of perineal trauma and its associated factors in nulliparous. Methods: A retrospective cohort study was carried out, through the analysis of the medical records of women with singleton pregnancy who achieved vaginal birth of a live infant, in 2017, in a maternity hospital. Data collection involved information about demographic, obstetric, and clinical data from nulliparous women, and infant birthweight. Univariate and multivariate logistic analyses were performed to verify the association of perineal trauma with the variables assessed, with significant variables remaining in the model (p<0.05), through a stepwise strategy. Results: A total of 326 medical records were analyzed. The percentage of perineal trauma was 60%. In the multivariate analysis, the use of oxytocin increased the chance of perineal trauma by 730%. In addition, the adoption of squatting position and hands and knees decreased the chances of perineal trauma by 81% and 97%, respectively, in comparison with those who adopted the lithotomy position, during the second stage labor. Conclusion: The rate of perineal laceration was high, but the severity was low. The use of oxytocin is associated with the presence of trauma and the squatting position and hands and knees, especially, have contributed to the protection of the perineum.
Innovation among SMEs in Finland: The impact of stakeholder engagement and firm-level characteristics
Authors:   Ph.D., University of Eastern Finland, Department of Health and Social Management, P.O. Box 1627, 70211, Finland, email: hannu.littunen@uef.fi, Littunen Hannu , Tohmo Timo ,   Ph.D, Jyväskylä University School of Business and Economics, P.O. BOX 35, 40100, Finland, email: timo.tohmo@jyu.fi, Storhammar Esa ,   Ph.D., Jyväskylä University School of Business and Economics, P.O. Box 35, 40100, Finland, email: esa.t.storhammar@jyu.fi
Published: November 2021

PURPOSE: The aim of the paper is to analyse the importance of both internal capabilities (resources) and external information sources in implementing product, process, marketing and organizational innovations aiming to maximize firm competitive advantage and create value for stakeholders. Furthermore, in particular, we examine the role of public organizations, business networks, firm size, and the industry sector, in the emergence of different types of product, process, marketing, and organizational innovations. The research was based on the typology of innovation (product, process, marketing, and organizational) adopted by the OECD. METHODOLOGY: The paper is based on data from 389 SMEs located in Finland and describes the development of a model for testing the factors that increase the innovativeness of SMEs. The logistic regression model is used as a methodology. Findings: The results show that the creation of novel products, processes and marketing innovation is connected to various external sources of information, such as fairs, the media and the internet. Moreover, the relationship between internal capabilities such as the firm’s know-how increases the marketing and organizational innovativeness of SMEs. Our results demonstrated that the creation of product innovation is positively connected to manufacturing. Furthermore, we find that the creation of novel processes and organizational innovation is related to firm size, such that firms with fewer than 20 employees (smallest firms) were concentrated among non-innovators and companies with more than 20 employees were concentrated among innovators. IMPLICATIONS FOR THEORY AND PRACTICE: The contribution of our study is to analyse to what extent various types of innovation rely on specific information sources. This study also provides suggestions for practice and policymakers. Contrary to expectations regarding our findings, public support organizations were not statistically significant in any innovation model. Therefore, public support organizations should develop better mechanisms to find SMEs with strong motivations to develop new products and market opportunities. ORIGINALITY AND VALUE: This paper provides a new and topical viewpoint for the literature by examining the possible factors explaining the increase in SMEs’ likelihood of implementing product, process, marketing, and organizational innovations. Our study provides comprehensive information on how different stakeholders contribute to the emergence of SME innovation.
Changing Trends of Antimicrobial Resistance in Neonatal Sepsis: Experience from a Tertiary Care Hospital from West Bengal, India
Authors: Dutta Manjula , Mitra Piyali , Nag Shankha Subhra , Dutta Abhijit
Published: November 2021

Introduction: Sepsis is the second leading cause of neonatal mortality in India. Emergence of highly resistant microorganisms as an aetiology of neonatal sepsis is a matter of serious concern. Aim: To study the prevailing aetiological agents in neonatal sepsis and their antimicrobial susceptibility pattern. Materials and Methods: A prospective observational study was performed in a tertiary care teaching hospital in neonatal care units in North Bengal Medical College and Hospital, West Bengal, India, over a period of two years from March 2017 to February 2019. All the neonates having clinical features suggestive of sepsis were subjected to blood culture using BacT/ALERT® PF Plus. Microbial identification and antibiotic susceptibility testing was done by VITEK-2 automated systems. Chi-square test was done using Epi info software version 7.1 and p-value <0.05 was considered significant. Results: Out of 403 neonates investigated for suspected sepsis, 156 (38.7%) were found to be culture positive. Klebsiella pneumoniae was the most common organism isolated (n=90, 57.7%) followed by Staphylococcus aureus (n=24, 15.4%) and Acinetobacter baumannii (n=10, 6.4%). Klebsiella pneumoniae showed a very high degree of resistance to ampicillin, amoxycillin- clavulenic acid (100% each), cefotaxime (93.4%), ceftazidime (92.3%), gentamycin (94.5%) and tobramycin (94.5%). High resistance of Staphylococcus aureus was seen against ampicillin (100%), cloxacillin (62.5%), amoxicillin-clavulenic acid (70.9%), and cefotaxime (79.2%). Few isolates of Klebsiella pneumonia (6.6%), Acinetobacter baumannii (60%) and Enterobacter cloacae (50%) were sensitive only to colistin and tigecycline. Conclusion: Most of the isolates showed very high degree of resistance against first line of antibiotics recommended by World Health Organisation (WHO) (ampicillin and gentamycin or amikacin) for empirical treatment of neonatal sepsis. Emergence of highly resistant organisms sensitive only to colistin and tigecycline should be considered as an eye opener. Strict adherence to sepsis prevention along with regular surveillance of organisms and their sensitivity patterns is the need of the hour to improve survival by contributing to antibiotic stewardship.
Historical and Current Perspective of Oyster Mushroom (Pleurotus ostreatus) Cultivation in South Korea
Authors: Lee Sang-Won , Cho Young-Son
Published: November 2021

We review edible mushrooms in South Korea, primarily focused on oyster mushroom (OM) (Pleurotus ostreatus), which shows the highest production among the mushrooms grown for industrial purposes, and it takes up almost 32% of the total production. We aimed to describe their historical uses, common cultivars, and specific characteristics that make them one of the most viable food sources or functional materials. About 15,000 mushroom varieties are known, and 2,000 varieties are possible as human food. Generally, OM has long been studied the most widely as an edible mushroom compared to the other mushrooms in South Korea. Recently, there has been a growing interest in food mushrooms as the production of O.M. is characterized by low greenhouse gas emissions compared to animal breeding in South Korea. Also, OM is often highlighted as nutritious side dishes to serve with rice. Thus, facilitating O.M. production and consumption could contribute to human health and environmental conservation in the near future. Over the years 2015–2020, Pleurotus sajor (PS) export increased by 189.9% (US$ 130,000) compared to 2010-2015. The O.M. cultivation tends to increase rapidly in developing countries for human food and compost or insect foods after cultivation, for example, internal use of culture media or sawdust dump of willow growing environmental conditions.

In South Korea, mushroom research has started in the 1960s by the horticultural research center of Rural Development of Administration. In the early 1970s, OM cultivation methods using paddy straw were first developed globally. In 1974, NONGGI-2-1-ho cultivar was developed. In 1976, various practices for water management, disinfection, and fermentation were developed, resulting in substantial yield increases. From 1986, labor-saving paddy straw binders, cutting machines, disinfection boilers, wager suppliers were produced and started being supplied to the farmers. In the 1980s, cotton waste was used as a substrate for cultivation of OM, where water content was identified as the dominant controlling factor for yields. Cotton waste is the best substrate material for summer OM. After using cotton waste, it is commonly replaced with paddy straw. Recently, growers use poplar sawdust, oak sawdust, and rice bran mixed at a ratio of 40:40:20 (v/v/v) instead of cotton waste. When adjusting the nutrients of a medium, the nitrogen content is the crucial factor in determining the yield of OM. There is an additional attempt to add functionality by using alternative plant materials, such as Hovenia dulcis known for liver protection and anti-cancer effects, as well as Acer tegmeutosum and Rhus verniciflura. Further research is in progress to search for and new medium materials effective for OM cultivation.
Climate Change Awareness among the Teachers of Higher Secondary Schools
Authors: Dorji Yeshi , Man Rai Chandra , Nidup Thukjey
Published: November 2021

Climate change has been a global threat, however, promoting awareness of climate change will reduce its risk. The study analyzed awareness on three aspects of climate change—causes, impacts, and mitigation among 90 teachers from three high schools, selected using stratified random sampling. We identified a total of 15 statements or variables from each of the causes, impacts, and mitigation to study the teacher’s awareness of climate change. We found that teachers have a medium level of awareness, being more aware of impacts than causes and mitigation of climate change. Three factors– teaching field, education level, and seminar attendance have significantly influenced the teachers’ awareness level on climate change. The result suggests that upgrading education, incorporating environmental studies in educational curriculum, and promoting seminar and workshop on environmental issues increases awareness on climate change.
Application of Trichoderma viride and Bacillus subtilis Leads to Changes in Antioxidant Enzymes, Proline, and Lipid Peroxidation under Salinity Stress in Chickpea (Cicer arietinum L.)
Authors: Kavita . , Sowmya Nagaram
Published: November 2021

The study was carried out to evaluate the influence of application of Trichoderma viride and Bacillus subtilis on antioxidant enzymes, proline and lipid peroxidation to decrease the impact of salinity stress on chickpea (Cicer arietinum L.), a salinity sensitive crop. A pot experiment was conducted with contrasting set of genotypes (tolerant vs. sensitive) under salinity stress compared to control soil conditions in completely randomized design with three replications. Microbial inoculation was done through seed priming and application to soil at 20 days after sowing (DAS). Content of antioxidant enzymes, proline, and lipid peroxidation were assessed in leaves at flowering stage. Results showed that antioxidant enzymes viz., catalase, peroxidase, and superoxide dismutase were significantly increased under salinity stress compared to control condition and they were further increased with application of microbes either as seed priming alone or in combination with soil application at 20 DAS in both the genotypes under saline as well as control conditions. The content of lipid peroxidation increased significantly under salinity stress, and it was stronger pronounced in sensitive genotype while the lipid peroxidation content was decreased by application of microbes. Proline content increased under salinity stress, and it was further enhanced by the microbial inoculation. The study thus conclusively proved that Bacillus subtilis and Trichoderma viride positively increased content of antioxidant enzymes, proline, and lipid peroxidation in leaves of chickpea grown under salinity stress conditions. The best microbe species was Trichoderma viride as seed priming plus soil application. This can be an important additional approach to decrease the impact of salinity stress on chickpea crop.
A Comparative Study to assess the Stress Buster among Working and Non-Working Women
Authors: Hinaz Z. Fathima , Devi R. Gayatri , Priya A. Jothi
Published: November 2021

Introduction: Stress is the body’s response to the daily events that occur in one’s life. Everyone experiences stress. Stress can be positive and motivate women to achieve notable goals. But stress can also be negative and destructive, taking its toll in many life areas. When stress becomes chronic or excessive, it becomes harder to adapt and cope. Chronic stress builds up so that stress seems like a normal way of life for some women. Women have undergone various different stresses, which vary from person to person. The objective of this study is to assess stress buster among working and non-working women.

Materials and Methods: This cross-sectional survey study carried out among working and non-working women. The total sample size was 103. A self administered questionnaire was used for the survey and was distributed through an online platform. Data was collected and analysed by Pearson and chi-squares test and p-value of 0.05 was said to be statistically significant.

Result: When compared to non working women, working women stress level was higher and they search for stress busters. Majority of the women population feel stressed, irritable, grouchy and anxious. Majority of the population also prefer listening to songs and also prefer to sing to overcome their stress.

Conclusion: Both working and non-working women are equally stressed, while non-working women tend to overreact to situations. Majority of the women population prefer listening to songs to overcome stress.
NADPH‐to‐NADH conversion by mitochondrial transhydrogenase is indispensable for sustaining anaerobic metabolism in Euglena gracilis
Authors: Nakazawa Masami , Takahashi Mutsuki , Hayashi Ryuta , Matsubara Yuki , Kashiyama Yuichiro , Ueda Mitsuhiro , Inui Hiroshi , Sakamoto Tatsuji
Published: November 2021

Euglena gracilis produces ATP in the anaerobic mitochondria with concomitant wax ester formation, and NADH is essential for ATP formation and fatty acid synthesis in the mitochondria. This study demonstrated that mitochondrial cofactor conversion by nicotinamide nucleotide transhydrogenase (NNT), converting NADPH/NAD+ to NADP+/NADH, is indispensable for sustaining anaerobic metabolism. Silencing of NNT genes significantly decreased wax ester production and cellular viability during anaerobiosis but had no such marked effects under aerobic conditions. An analogous phenotype was observed in the silencing of the gene encoding a mitochondrial NADP+‐dependent malic enzyme. These results suggest that the reducing equivalents produced in glycolysis are shuttled to the mitochondria as malate, where cytosolic NAD+ regeneration is coupled with mitochondrial NADPH generation.
Prevalence of Early Knee Osteoarthritis Illness Among Various Patient‐Reported Classification Criteria After Anterior Cruciate Ligament Reconstruction
Authors: Harkey Matthew S. , Baez Shelby , Lewis Jordan , Grindstaff Terry L. , Hart Joseph , Driban Jeffrey B. , Schorfhaar Andrew , Kuenze Christopher
Published: November 2021

Objective

To compare the prevalence of participants meeting different patient‐reported criteria for early osteoarthritis (OA) illness after anterior cruciate ligament reconstruction (ACLR).

Methods

Participants completed the Knee Injury and Osteoarthritis Outcomes Score (KOOS) at a single time point 5.0–7.9 months post‐ACLR. We used established KOOS subscale criteria (i.e., Luyten original and Englund original) to define patient‐reported early OA illness. A two‐by‐two contingency table and McNemar's test were used to compare the prevalence of participants who met the Luyten original versus Englund original KOOS criteria for early OA illness. These analyses were repeated using KOOS subscale thresholds based on established population‐specific patient acceptable symptom state (PASS) within the Luyten and Englund KOOS criteria (i.e., Luyten PASS and Englund PASS).

Results

A greater prevalence of participants with ACLR met the Luyten original criteria (n = 165 [54%]) compared to those who met the Englund original criteria (n = 128 [42%]; χ2 = 19.3, P < 0.001). When using the KOOS subscale PASS as thresholds, a significantly greater prevalence of participants with ACLR met the Luyten PASS criteria (n = 133 [43%]) compared to those who met the Englund PASS criteria (n = 85 [28%]; χ2 = 48.0, P < 0.001). When combining the Luyten and Englund KOOS criteria and using the original/PASS subscale thresholds, respectively, 40%/57% of participants met neither, 24%/15% met only 1, and 36%/28% met both KOOS criteria.

Conclusion

Regardless of the classification criteria used to define early OA illness, it is concerning that 28–54% of patients report considerable symptoms ~6 months post‐ACLR. Our findings will improve the classification criteria to define early OA illness, which may raise awareness for the need of population‐specific criteria.
Significant Enhancement in the Thermoelectric Properties of Ionogels through Solid Network Engineering
Authors: Liu Zhuo , Cheng Hanlin , He Hao , Li Jianbo , Ouyang Jianyong
Published: November 2021

Thermoelectric (TE) materials are significant for sustainable development because they can be used to directly harvest heat into electricity. Recently, ionic TE materials emerged as very promising materials mainly due to their high thermovoltage that can be higher than the Seebeck coefficient of electronic TE materials by 2–3 orders in magnitude. However, their conductivity is very low. Here, the significant improvement in the ionic conductivity and thus the overall TE properties of ionogels is reported by engineering their solid networks, which immobilize the ionic liquid in the ionogels. An antisolvent of poly(vinylidene fluoride‐co‐hexafluoropropylene) (PVDF‐HFP) is added into the acetone solution of 1‐ethyl‐3‐methylimidazolium dicyanamide (EMIM:DCA) that is an ionic liquid and PVDF‐HFP prior to the ionogel formation. This can significantly change the solid networks formed by PVDF‐HFP and thus the microstructure of the EMIM:DCA/PVDF‐HFP ionogels, thereby facilitating ionic transport. As a result, the ionic conductivity of the ionogels can be increased from 7.0 to 17.6 mS cm−1. The ionogels can exhibit a high ionic figure of merit (ZTi) of 1.8 with the ionic Seebeck coefficient of 25.4 mV K−1 and the thermal conductivity of 0.190 W m−1 K−1. This is the highest recorded ZTi value for ionic conductors.
Can Laminated Carbon Challenge Gold? Toward Universal, Scalable, and Low‐Cost Carbon Electrodes for Perovskite Solar Cells
Authors: Sepalage Gaveshana A. , Weerasinghe Hasitha , Rai Nitish , Duffy Noel W. , Raga Sonia R. , Hora Yvonne , Gao Mei , Vak Doojin , Chesman Anthony S. R. , Bach Udo , Simonov Alexandr N.
Published: November 2021

While perovskite solar cell (PSC) efficiencies are soaring at a laboratory scale, these are most commonly achieved with evaporated gold electrodes, which would present a significant expense in large‐scale production. This can be remedied through the use of significantly cheaper carbon electrodes that, in contrast to metals, also do not migrate through the device. To this end, the present work investigates simple‐to‐prepare aluminum‐supported carbon electrodes derived from commercially available, inexpensive materials that can be applied onto various hole‐transporting materials and enable photovoltaic performances on par with those provided by gold electrodes. Successful integration of the new carbon‐based electrode into flexible devices produced by a roll‐to‐roll printing technology by both pressing and lamination is demonstrated. However, temperature cycling durability tests reveal that the use of carbon electrodes based on commercial pastes is hindered by incompatibility of adhesive additives with the key components of the PSCs under heating. Resolving this issue, tailor‐made graphite electrodes devoid of damaging additives are introduced, which improve the PSC stability under temperature cycling test protocol to the level provided by benchmark gold electrodes. The study highlights current challenges in developing laminated carbon electrodes in PSCs and proposes strategies toward the resolution thereof.
Integrated metal–organic framework and pressure/vacuum swing adsorption process design: Descriptor optimization
Authors: Zhang Xiang , Zhou Teng , Sundmacher Kai
Published: November 2021

An integrated metal–organic framework (MOF) and pressure/vacuum swing adsorption (P/VSA) process design framework is presented for gas separation. It consists of two steps: adsorbent descriptor optimization, and MOF matching. In the first step, MOFs are represented as a large set of chemical and geometric descriptors from which the most influential ones are selected via a multistep screening method and treated as design variables. The valid design space of the selected descriptors is confined using a tailored classifier model and logic constraints. Based on collected adsorption isotherms of 471 different MOFs, data‐driven isotherm models are developed. Combining the design space, isotherms, and four‐step P/VSA process models, an integrated MOF and P/VSA process design problem is formulated. MOF descriptors and process operating conditions are optimized to maximize the process performance. The obtained optimal descriptors and isotherms can be used to guide the discovery of high‐performance MOFs in a subsequent MOF matching step. This article addresses the first descriptor optimization step exemplified by propene/propane separation.
Passive Harmonic Mode‐Locked Erbium‐Doped Fiber Laser Based on ZrTe3 Nanoparticle‐Based Saturable Absorber
Authors: Hui Zhanqiang , Shen Niping , Wang Yuanhong , Han Dongdong , Li Tiantian , Zhou Hua , Gong Jiamin
Published: November 2021

2D layer‐structured nanomaterials have attracted much attention owing to their excellent optical, electrical, and magnetic properties. In this study, a novel 2D zirconium tritelluride (ZrTe3) nanosheet material is prepared. The nonlinear saturated absorption characteristics of the ZrTe3 nanosheets are studied using the double‐equilibrium detection method. The saturation intensity and modulation depth are 100.6 MW cm−2 and 3.3%, respectively. A saturable absorber (SA) based on ZrTe3 is used in a harmonic passive mode‐locking erbium‐doped fiber laser for the first time. The results show that when the pump power is 50 mW, mode‐locking with a fundamental frequency of 5.82 MHz is achieved. The pulse width, center wavelength, 3 dB bandwidth, and signal‐to‐noise ratio (SNR) are 1.44 ps, 1563.7 nm, 2.31 nm, and 76 dB, respectively. With an increase in pump power, a high repetition rate of 483.1 MHz, corresponding to the 83‐order harmonic mode‐locked, is obtained at a pump power of 310 mW. The pulse width, 3 dB optical spectral width, and SNR are 1.302 ps, 3.14 nm, and 67 dB, respectively. This reveals that ZrTe3 nanosheets are excellent photonic materials that can be used to generate high‐repetition‐rate pulse lasers and have great application potential in ultrafast photonics.
Accessing Unsymmetrically Linked Heterocycles through Stereoselective Palladium‐Catalyzed Domino Cyclization
Authors: Arora Ramon , Rodríguez José F. , Whyte Andrew , Lautens Mark
Published: November 2021

A palladium‐catalyzed strategy is presented to synthesize unsymmetrically linked heterocycles within stereoselective tetrasubstituted olefins. This reaction is proposed to occur via a vinyl‐PdII intermediate capable of initiating the cyclization of various alkyne‐tethered nucleophiles. Products are formed in up to 96 % yield and excellent stereoselectivities are obtained using low catalyst loadings. This transformation was scalable up to 1 mmol and mechanistic studies suggest a syn‐carbopalladation of the carbamoyl chloride followed by PdII‐catalyzed cyclization of alkyne‐tethered nucleophiles.
Concurrent Prebiotic Formation of Nucleoside‐Amidophosphates and Nucleoside‐Triphosphates Potentiates Transition from Abiotic to Biotic Polymerization
Authors: Lin Huacan , Jiménez Eddy I. , Arriola Joshua T. , Müller Ulrich F. , Krishnamurthy Ramanarayanan
Published: November 2021

Polymerization of nucleic acids in biology utilizes 5′‐nucleoside triphosphates (NTPs) as substrates. The prebiotic availability of NTPs has been unresolved and other derivatives of nucleoside‐monophosphates (NMPs) have been studied. However, this latter approach necessitates a change in chemistries when transitioning to biology. Herein we show that diamidophosphate (DAP), in a one‐pot amidophosphorylation‐hydrolysis setting converts NMPs into the corresponding NTPs via 5′‐nucleoside amidophosphates (NaPs). The resulting crude mixture of NTPs are accepted by proteinaceous‐ and ribozyme‐polymerases as substrates for nucleic acid polymerization. This phosphorylation also operates at the level of oligonucleotides enabling ribozyme‐mediated ligation. This one‐pot protocol for simultaneous generation of NaPs and NTPs suggests that the transition from prebiotic‐phosphorylation and oligomerization to an enzymatic processive‐polymerization can be more continuous than previously anticipated.