bluuebunny/crossref_metadata_2025 huggingface dataset:
After Finitude and the Question of Phenomenological Givenness
Authors: Pearl J. Leavitt
Published: July 2018

Quentin Meillassoux’s 2006 After Finitude offered a sharp critique of the phenomenological project, charging that phenomenology was one of the “two principal media” of correlationism—ultimately reducible to an “extreme idealism.” Meillassoux grounds this accusation in an account of givenness that presupposes that “every variety of givenness” finds its genesis within the positing of the subject. However, this critique fails to hit its mark precisely because it presupposes an account of intuitive givenness that is entirely foreign to the phenomenological project. Quite against Meillassoux’s conflation of givenness, the world-for-us, and the positing subject—the very centre of the phenomenological project is the recognition that intuitive givenness cannot be reduced to the constructive activity of the subject. Givenness is marked by a heterogeneity; givenness refers to what is given to us, not to what emerges from us.
Merleau-Ponty, Correlationism, and Alterity
Authors: Booth Robert
Published: July 2018

A common commitment amongst speculative realists holds that phenomenology is irredeemably hostile to nonhuman alterity because phenomenology is correlationist. Since phenomenologists deny unmediated access to the modality of the in-itself, their correlationism purportedly consists in subsuming the more-than-human world into one’s own (narrowly anthropocentric) intentional horizon, a move that promises correspondingly disastrous environmental implications. Merleau-Pontian phenomenology appears to be especially guilty in this regard since Merleau-Ponty argues that taking our situated embodiment sufficiently seriously entails that any other entity encountered must always take the form of an “in-itself-for-us.” In this paper, I argue that the charge of correlationism against Merleau-Pontian phenomenology can be disarmed because it is either false or insubstantial. In either case, I argue, if we are to remain sufficiently open to more-than-human alterity to evade the dangerous sort of anthropocentrism that anticorrelationists rightly speak against, we would do well to retain the very subject-object ambiguity that motivates the correlationist charge against Merleau-Pontian phenomenology in the first place.
Excess and Withdrawal: Critical Phenomenology and Speculative Realism
Authors: Zielke Dustin
Published: July 2018

This paper takes up the problem of correlationism from a phenomenological perspective. Speculative realists, such as Quentin Meillassoux and Graham Harman, seek to establish new forms of Continental realism largely because, in their view, phenomenology cannot adequately account for the real. To counter these claims, I will use what I call a “critical phenomenological approach”, which critically delimits the real from the intentional relation, and thus makes possible a phenomenological theory of the real. This approach to realism establishes not only that the real is independent from the intentional relation but also that the intentional relation itself is contingent with regard to the real. Furthermore, it also shows that the human being is exposed to the real in an originary way that calls into question the adequacy of Meillassoux’s and Harman’s forms of realism.
COLONIAL LEGACIES AND COMPETING MASCULINITIES: THE SUPREME COURT OF CANADA’S RETURN TO REASON IN R. V. KAPP
Authors: Hodes Caroline
Published: July 2018

This article examines a series of unarticulated gender dynamics that shaped some of the recent changes to the legal test for discrimination under s. 15 of the Canadian Charter of Rights and Freedoms. Despite the volume of literature that references R. v. Kapp, none of it has specifically addressed how race is gendered through the claims of the accused, the witnesses who testified on their behalf or the decisions of the judges who interpreted their testimony. Revisiting the legal strategies used in this case reveals ongoing challenges to accessing justice for marginalized groups and impediments to reconciliation.
TRANSITIONAL JUSTICE AND THE CHALLENGING PURSUIT OF SOCIAL JUSTICE
Authors: Kastner Philipp
Published: July 2018

This article argues that the shortcomings of the currently dominant transitional justice model, which largely ignores considerations of social justice, can be explained by several structural factors within the international legal system. It considers the relatively recent establishment of transitional justice institutions and argues that despite different forms – international criminal tribunals, truth and reconciliation commissions, peoples’ tribunals – these institutions are motivated by similar rationales and have the same underlying objectives. These parallels, enhanced by the both explicit and implicit normative influences that the respective institutions have on each other, and the overly linear notion of time embedded in international law have given rise to a problematic model of transnational transitional justice. Among others, this model hinders the pursuit of social justice beyond a narrow focus on individual human rights and individualized responsibilities for specific crimes. The article calls for a deliberate turn away from prefabricated institutional responses as well as for a much-needed reconceptualization of the prevailing model of justice within international legal discourses in order to address structural inequalities and forms of injustice that are often part of the root causes of armed conflicts.
“Para mim Deus é isto: a beleza que se ouve no silêncio” - Do irracional de Otto à estética em Rubem Alves
Authors: Martins Gustavo Claudiano , Vasconcellos Danilo Souza Mendes de
Published: July 2018

Juntando-se às comemorações dos 500 anos de Reforma protestante, 100 anos de O Sagrado e 30 anos de Sobre deuses e caquis, esta pesquisa visa apresentar Rubem Alves como leitor de Rudolf Otto entendendo de que forma a ideia de irracional dele contribui para a elaboração da religiosidade estética que se encontra em Rubem. Inicia-se esta jornada mapeando as possíveis influências de Otto em Alves; segue-se apresentando a forma como este entende a religião em face à estética e a aproximação entre Deus e a beleza; por fim, percebe-se os desdobramentos da passagem de uma religiosidade ética a uma religiosidade estética. Com estes desdobramentos, pode-se justificar a relevância desta pesquisa: seguindo a tradição de Otto, Alves parece reconhecer os elementos racionais e irracionais da religião, os aspectos éticos e estéticos sem, contudo, negar a realidade de uma destas faces em afirmação à outra. Nesta percepção, afirma-se a irredutibilidade do fenômeno religioso a um só âmbito.
Richard Hooker e a Epístola de Tiago reconciliada com a justificação pela fé no século XVI
Authors: Rios Cesar Motta
Published: July 2018

A relação entre Tiago e a doutrina da justificação pela fé tem ocupado teólogos protestantes por séculos. Por meio de pesquisa bibliográfica em fontes primárias e secundárias, apresento Richard Hooker, importante teólogo da Igreja da Inglaterra no século XVI, e seu entendimento sobre o problema. Após uma apresentação do teólogo, justificada por se tratar de personagem praticamente não estudado em nosso contexto, exponho a doutrina da justificação pela fé conforme Hooker e sua conciliação com Tiago. Em seguida, demonstro que ele não está isolado em sua proposta, mas é antecedido por Melanchthon e Calvino, que, como ele, divergem de Lutero. Por fim, observo como sua proposta condiz com sua postura com relação a outras igrejas além dos limites da Inglaterra, e como seu exemplo pode ser proveitoso para o diálogo ecumênico hoje.
Deus "sai do armário"? Algumas considerações teológicas sobre a homoafetividade
Authors: Pinto Carlos Rafael
Published: July 2018

Dentro e fora da Igreja Católica, nas últimas décadas, constata-se que a realidade homoafetiva clama atenção, sobretudo por estar intimamente associada à violência, exclusão, discriminação. À luz da experiência do Filho de Deus, vou me deixar guiar pela intuição, segundo a qual, na experiência homoafetiva, Deus “sai do armário”. Por conseguinte, cabe-nos na reflexão teológica e no serviço apostólico reconhecer que Deus se revela também nessa realidade tendo, pois, que assumi-la como locus theologicus.
Effect of temperature on seed germination vegetable crops umbelliferae
Authors: Baleev D N , Buharov A F
Published: July 2018

The effect of temperature during germination of seeds of some species of vegetable crops umbelliferae. The different cultures react differently to the temperature factor: change the number of days until the maximum rate of growth and percentage of germinated seeds. The effect of temperature on the growth of the embryo in the seeds of the studied cultures. Studied in different cultures. Was analyzed the “degree of underdevelopment of the embryo” (DUE), which characterizes the morpho-anatomical features of the embryo. The temperature coefficient (Q 10) for the rate of growth of the embryo umbrella vegetable crops.
Biological evaluation of honey
Authors: Dolgov V A , Lavina S A , Arno T S , Semyonova E A , Nikitchenko D V , Seryogin I G
Published: July 2018

The article shows the results of the use of ciliates Tetrahymena pyriformis, for biological evaluation of honey. It is known that ciliates Tetrahymena pyriformis, similar in general characteristics of metabolism with higher animals, can serve as sufficient testing organism during biological evaluation of honey which is a good nutrient substrate for these simple. The main criteria of harmlessness and biological usefulness of honey is its growth promoting effect which is appliable to ciliates Tetrahymena pyriformis.
Aminotransferases in tissues of in piglets cecum
Authors: Terentyeva M G , Mardaryeva N V
Published: July 2018

Defined the aminotransferases in the tissues of the three parts of the intestines (proximal and medial and distal) at growing of pigs. Different character of age changes of enzymes activity in tissues of piglets was detected.
A fuga da escravidão imperial: Benedita Luiza os jogos de fronteira entre novos Estados (Bolívia e Brasil)
Authors: De Sena Ernesto Cerveira
Published: July 2018

Em 1850, momento em que uma nova lei antitráfico entrava em vigor no Brasil, Benedita Luiza, uma escrava, empreende fuga do Império, em Mato Grosso, até a Bolívia. Com esse episódio foram suscitados problemas típicos dos novos países modernos que surgiam, como os relacionados à soberania, e até onde iriam a territorialidade nacional, a legitimidade da “propriedade” em contraposição à fuga internacional. O texto mostra que, em meio a essas discussões, os representantes do Império aproveitaram tal momento para ocupar e praticamente sedimentar ocupações nas áreas fronteiriças. A Bolívia, por seu turno, em posição mais frágil na fronteira, se mostrou receptiva aos fugitivos do Brasil, o que poderia trazer possibilidades de barganha em um acordo internacional sobre limites, que seria realizado mais cedo ou mais tarde.
JUNQUEIRA, Mary Anne. Velas ao mar: U.S. Exploring Expedition (1838-1842). A viagem científica de circum-navegação dos norte-americanos. São Paulo: Intermeios, 2015.
Authors: Santos Junior Valdir Donizete dos
Published: July 2018

Resenha do livro JUNQUEIRA, Mary Anne. Velas ao mar: U.S. Exploring Expedition (1838-1842). A viagem científica de circum-navegação dos norte-americanos. São Paulo: Intermeios, 2015.
El sentido de las cosas en la metáfora
Authors: Jemio Arnez Kathya
Published: July 2018

Quien está en la búsqueda de herramientas para la construcción y revelación de significados ambiguos, ocultos o debajo de otros significados, muchas veces con el interés de ampliar el sentido, confundir la generalización con la especificidad de un concepto o desdibujar los límites de interpretación, se encuentra con la metáfora. Constituye un mecanismo para comprender y expresar conceptos complejos, sirviéndose de conocimientos elementales. Umberto Eco entiende que el lenguaje es por naturaleza y originariamente metafórico, por tanto toda regla surge con el fin de empobrecer el potencial metafórico que define al hombre como animal simbólico (Bustos 1999: 98). En su origen la metáfora es histórica porque su producción aparece en las sociedades y colectivos humanos que en el transcurso de su desarrollo y según sus circunstancias cotidianas materiales y culturales se apropian de la expresión, de esto resulta que los eventos cotidianos son fuente de su formación.
Del imaginario urbano a una aproximación de ciudadanía educada
Authors: Díaz Arenas Pedro Felipe
Published: July 2018

El presente texto es una mirada previa al estudio de los imaginarios urbanos, busca identificar el imaginario y el concepto de ciudadanía como fenómeno de ciudadanos educados. Las experiencias de cotidianidad van creando rutas y rutinas, que al ser indagadas remiten a un modo de ser ciudadano. En este sentido la ciudad es el lugar donde converge y se producen nuevas formas de percibir y de vivir. Este avance está enmarcado en las teorías y metodologías del doctor Armando Silva en el marco del proyecto internacional de ciudades imaginadas en el año de 1994.
Difference schemes for the semilinear integral-differential equation of the hyperbolic type
Authors: Direk Zilal , Ashyraliyev Maksat
Published: July 2018

In this paper, the initial-value problem for integral-differential equation
of the hyperbolic type in a Hilbert space H is considered. The unique
solvability of this problem is established. The first order and the second
order of accuracy difference schemes approximately solving this problem are
presented. The convergence estimates for the solutions of these difference
schemes are obtained. Theoretical results are supported by numerical
example.
The use of soft matrices on soft multisets and their applications in optimal decision process
Authors: Coşkun Arzu , Aras Gündüzğdem , Sönmez Ayşe
Published: July 2018

In this paper, we introduce a concept of a soft matrix on a soft multiset,
and investigate how to use soft matrices to solve decision making problems. An
algorithm for a multiple choose selection problem is also provided. Finally,
we demonstrate an illustrative example to show the decision making steps.
Sufficient conditions for Carathéodory functions
Authors: Nunokawa Mamoru , Kwon Oh , Sim Young , Cho Nak
Published: July 2018

In the present paper, we obtain several sufficient conditions for Carath?odory
functions in the open unit disk U = {z ? C : ?z? < 1}. We also obtain
sufficient conditions for p-valent or starlike functions. Moreover, we improve
some results due to Nunokawa [Tsukuba J. Math. 13 (1989), 453-455] as some
special cases of main results.
Necessary optimality condition for the singular controls in an optimal control problem with nonlocal conditions
Authors: Safari Ali , Sharifov Yagub , Gasimov Yusif
Published: July 2018

In this paper, we continue investigation of the problem considered in our
earlier works. The paper deals with an optimal control problem for an
ordinary differential equation with integral boundary conditions that
generalizes the Cauchy problem. The problem is investigated the case when
Pontryagin?s maximum principle is degenerate. Moreover, the second order
optimality conditions are derived for the considered problem.
One-dimensional Schrodinger operator with a negative parameter and its applications to the study of the approximation numbers of a singular hyperbolic operator
Authors: Muratbekov M.B. , Muratbekov M.M.
Published: July 2018

In this paper we use the one-dimensional Schr?dinger operator with a
negative parameter to the study of the approximation numbers of a hyperbolic
type singular operator. Estimates for the distribution function of the
approximation numbers are obtained.
Determination of a time-dependent heat source under not strengthened regular boundary and integral overdetermination conditions
Authors: Sadybekov Makhmud , Oralsyn Gulaiym , Ismailov Mansur
Published: July 2018

We investigate an inverse problem of finding a time-dependent heat source in
a parabolic equation with nonlocal boundary and integral overdetermination
conditions. The boundary conditions of this problem are regular but not
strengthened regular. The principal difference of this problem is: the system
of eigenfunctions is not complete. But the system of eigen- and associated
functions forming a basis. Under some natural regularity and consistency
conditions on the input data the existence, uniqueness and continuously
dependence upon the data of the solution are shown by using the generalized
Fourier method.
On some generalizations of properties of the Lowndes operator and their applications to partial differential equations of high order
Authors: Karimov Shakhobiddin
Published: July 2018

In this work we proved a composition of Lowndes? operator with differential
operators of the high order, particularly, with iterated Bessel differential
singular operator. Examples on applications of the proved properties to
partial differential equations of the fourth and high order with singular
coefficients were showed. By applying the proved theorems, explicit formulas
of the solutions of considered problems were constructed.
Isoperimetric inequalities for the Cauchy-Dirichlet heat operator
Authors: Kal’menov Tynysbek , Kassymov Aidyn , Suragan Durvudkhan
Published: July 2018

In this paper we prove that the first s-number of the Cauchy-Dirichlet heat
operator is minimized in a circular cylinder among all Euclidean cylindric
domains of a given measure. It is an analogue of the Rayleigh-Faber-Krahn
inequality for the heat operator. We also prove a Hong-Krahn-Szeg? and a
Payne-P?lya-Weinberger type inequalities for the Cauchy-Dirichlet heat
operator.
Isoperimetric inequalities for the heat potential operator
Authors: Kal’menov Tynysbek , Kassymov Aidyn , Suragan Durvudkhan
Published: July 2018

In this paper we prove that the circular cylinder is a maximizer of the
Schatten p-norm of heat potential operator among all Euclidean cylindric
domains of a given measure. We also give analogues of a Rayleigh-Faber-Krahn
and a Hong-Krahn-Szeg? type inequalities.
Differential operator equations with interface conditions in modified direct sum spaces
Authors: Aydemir Kadriye , Olğar Hayati , Mukhtarov Oktay , Muhtarov Fahreddin
Published: July 2018

We investigate a new type boundary value problem consisting of a
differential-operator equation, eigendependent boundary conditions, and two
supplementary conditions so-called interface conditions. We give a
characterisation of some spectral properties of the considered problem.
Particularly, it is established such properties as isomorphism and
coerciveness, discreteness of the spectrum and found asymptotic formulas for
eigenvalues.
About solvability of some boundary value problems for poisson equation in the ball
Authors: Koshanova Maira , Turmetov Batirkhan , Usmanov Kairat
Published: July 2018

In the paper we study properties of some integro - differential operators of
fractional order. As an application of the properties of these operators for
Poisson equation we examine questions on solvability of a fractional
analogue of the Neumann problem and analogues of periodic boundary value
problems for circular domains. The exact conditions for solvability of these
problems are found.
Smirnov A.V. Social and political conflict as an inherent feature of the transitive Russian society
Authors:   Voronezh State Medical University, Ruzhentsev Sergey Evgenievich , Smirnov Aleksey Valentinovich ,   Voronezh State Medical University
Published: July 2018

The study deals with the origins and nature, causes and peculiarities of the conflict situation in the modern Russian society and its political system. In the authors’ opinion, the diverse social conflicts in the post-Soviet Russia are due to the complex inter-action of divergent trends in the society’s develop-ment and different contradictions that are associat-ed with the intertwining of the pre-Soviet, Soviet and liberal market types of social processes. The re-search highlights that the persistent conflict-prone nature of the Russian society is considerably aggra-vated by the ongoing inability to choose the coun-try’s development strategy and ways of regulating contradictions. Besides, the situation is obviously exacerbated by the incomplete modernization re-forms of the country leading to the permanent lack of collaboration between the social institutions and political ones, the weak regulatory mechanisms, the persistent social polarization in society, the social tension, the strategic fragility of the economic de-velopment. As a result, marginalization and the sub-stantial social disparity immanently generate social and political contradictions, keep the transitional nature of the Russian society at large and transmit it to the future.
Arctic interests of South Korea
Authors:   Russian Presidential Academy of  National Economy and Public Administration, Epshteyn Vitaly Anatolievich , Takhaeva Albika Ruslanovna ,   Russian Presidential Academy of  National Economy and Public Administration
Published: July 2018

The research discusses the main reasons for South Korea’s interests in the Arctic region. The mile-stones of development of South Korea’s Arctic poli-cy are examined as well. The Arctic policy of the Republic of Korea includes the periods from the first studies in the late 1980s up to an active Arctic re-search due to the launch of the Arctic research sta-tion (Arctic Dasan Station) in Spitsbergen, Norway in 2002. Furthermore, it implies the periods when South Korea has been granted the temporary ob-server status of the Arctic Council in 2008 and when the first icebreaker has been built in 2009 up to 2013 when it has been granted the permanent observer status of the Arctic Council, its economic involve-ment has been increased and the Arctic Policy Mas-ter Plan for 2013–2017 has been presented.
The role of legal culture in the civil society development
Authors:   Mordovia State National Research University, Usmanova Elena Fanilyevna
Published: July 2018

The study analyzes the role of legal culture in creat-ing and developing the civil society. The research notes that the social and cultural capacity enhance-ment of legal culture, its improvement will upgrade and facilitate the effective development of the insti-tutions of civil society. Legal culture is the basis for the harmonious development of society, contributes to the overall social progress and the development of legal values that enrich the personality and guar-antees that the fundamentals of the civil society and its functioning will be kept. The author concludes that the modern Russian society characterized by its ethnic, social and cultural peculiarities, its own level of legal culture, legal mentality can build the civil society if the key elements (effective legislation, development of the institution of human rights, au-thority reforms, offense prevention, mass legal edu-cation and instruction, legal humanization) are im-plemented.
Legislative regulation of lobbying in the United States and its development challenges in Russia
Authors:   Financial University  under the Government of the Russian Federation, Medvedeva Evgeniya Aleksandrovna , Mikhailu Ekaterina Maksimovna ,   Financial University  under the Government of the Russian Federation
Published: July 2018

The study deals with the problem, purpose and functions of lobbying in the modern civil society. The development challenges of the institution of lobbying in the Russian Federation are revealed. The research examines and presents the laws on lobby-ing applied abroad. In particular, the successful American practices in this regard are reviewed. Vari-ous forms and methods of lobbying in the United States are revealed as well. The study highlights the problematic aspects of the legislative regulation of lobbying in the Russian Federation. The research analyzes and identifies the positive aspects of the legal consolidation of the term ‘lobbying’ in the Russian law. The authors propose ways to integrate the best American achievements into the Russian society considering the specific features of the legal and economic structure of the Russian Federation. The positive aspects of the development of lobbying practices in Russia are determined.
Weight loss therapy for obstructive sleep apnea – Literature review
Authors: Patrascu Elena , Manea Claudiu
Published: July 2018

Obstructive sleep apnea is a chronic disease characterized by the appearance of apnea or hypopnea episodes during sleep. This condition is associated with several risk factors. Among them, the most important is obesity and it is the only potentially curable. The treatment is polimodal and it involves several therapeutic directions. The purpose of this paper is to establish the role of obesity in the etiology of sleep apnea, as well as the role of the weight loss in its management, both through intensive lifestyle interventions and surgical therapy.
Comparison of the thermal effects of Coblation and Radiofrequency waves in a porcine turbinate model
Authors: Vogt Klaus , Daine-Loza Inese , Sperga Maris
Published: July 2018

BACKGROUND. Radiofrequency reduction and Coblation are widely used procedures for the treatment of functionally enlarged turbinates with an appropriate outcome. Bleeding and crusting are postoperative complications for Coblation. Thermographic measurements and histological analyses were used to elucidate the causes.

MATERIAL AND METHODS. In a porcine turbinate model, double-needle electrodes of different lengths were tested using a 4MHz radiofrequency current with either automatic energy limitation or a predetermined energy amount of 200 J. Coblation, according to the manufacturer’s instructions, was carried out with a Reflex Ultra 45 wand. The generated temperature was measured with thermo-probes at the tip of the electrodes. The mucosa was subsequently investigated histologically.

RESULTS. Without preoperative saline injection, all procedures generate temperatures < 100° C. After saline injection, excessive temperatures are reached by Coblation after the release of plasma in a closed system. The follow-up is a severe deterioration of the microscopic structures of the mucosa. The low-temperature advantages of Coblation are only effective if the mandatory saline solution rinses the surface. The Radiofrequency applications deliver more predictable results.

CONCLUSION. For the treatment of the functional enlargement of the turbinates, Radiofrequency current with proofed settings should be chosen.
Small cell neuroendocrine carcinoma: A rare second primary malignancy after treatment of nasopharyngeal carcinoma
Authors: Madhusudhan Krishnamoorthy , Hassan Nor Eyzawiah binti , Shukri Norasnieda binti Md , Hitam Shahrul bin , Bakrin Ikmal Hisyam bin
Published: July 2018

Small cell neuroendocrine carcinoma (SCNEC) of the nasopharynx and nasal cavity is a rare condition. It is an aggressive malignancy with a high recurrence rate. Despite its rarity in the sinonasal region, it may occur as a second primary malignancy. Patients with cancer of the head and neck region are more prone to develop a second primary tumor due to the field cancerization phenomenon, and a higher incidence is seen in those who have previously received radiation therapy. A detailed clinical and histopathological examination is pivotal to diagnose SCNEC as a second primary malignancy. We wish to highlight such a peculiar case from our center.
Abducens nerve palsy on a patient with sphenoid fungal rhinosinusitis and cavernous sinus meningioma – Case report
Authors: Marza Andreea , Manea Claudiu
Published: July 2018

We report a case of a 47-year-old patient recently diagnosed with left abducens nerve palsy, who was admitted in our clinic with diplopia. The cranio-facial CT scan revealed left sphenoid fungal rhinosinusitis and the patient underwent endoscopic surgery with complete removal of the fungal material. The immediate postoperative evolution of the patient was favourable, with partial improvement of diplopia. The first month follow-up visit revealed the recurrence of the diplopia, so the patient performed an MRI scan of the brain that showed a cavernous sinus meningioma. The patient was referred to a neurosurgeon who choose a “wait-and-see” strategy instead of surgery.

The paper presents the limits of computed tomography versus magnetic resonance imaging in the radiologic diagnosis of intracranial tumors.
THE INFLUENCE OF PERIPHERAL CHEMOREFLEX SENSITIVITY ON THE CRITICAL INCIDENTS RATE DURING COMBINED ANESTHESIA
Authors: TREMBACH N. V.
Published: July 2018

Aim. The goal of the study was to assess the impact of peripheral chemoreflex sensitivity on the rate of critical incidents in extensive abdominal operations.Materials and methods. The study included 176 patients who underwent major abdominal surgery under combined anesthesia. On the eve of surgery, sensitivity of peripheral chemoreflex was determined in all subjects. Sex, age, initial physical status, cardiovascular risk were also registered. During anesthesia hemodynamic, respiratory and metabolic critical incidents were registered.Results. In total, 158 critical incidents were observed. They were significantly more common in patients with high sensitivity to peripheral chemoreflex (72% vs. 48%, p<0.05). The structure of critical incidents was dominated by hemodynamic, primarily hypotension, and its frequency was 2 times higher among patients with high sensitivity of peripheral chemoreflex.The logistic regression showed that factors associated with the risk of critical incidents are high sensitivity of peripheral chemoreflex, increased age, and initially high grade of ASA scale.Conclusion. Hemodynamic incidents are the most common in major abdominal surgery; risk factors for their development are high sensitivity of peripheral chemoreflex, increased age and deterioration of the initial physical status.
LONG-TERM RESULTS OF THE MICROSURGICAL TREATMENT OF THE CEREBRAL ANEURYSM RUPTURES IN PATIENTS AT A COMPENSATED STATE
Authors: SHAGAL L. V. , TKACHEV V. V. , SHAGAL V. V. , BLUMENAU I. S. , ZABOLOTSKIKH N. V. , MUZLAEV G. G.
Published: July 2018

Aim. To study the severity of cognitive and psychoemotional disorders in the outcome of treatment of the patients with cerebral aneurysms ruptures, who were admitted in a compensated condition.Materials and methods. 57 cases are analyzed in the article. These are the cases of patients who were operated on in an acute state of aneurysmal subarachnoid hemorrhage. The severity of their state when they were admitted was 1-3 according to the Hunt-Hess scale. Depending on the results of treatment, the patients were divided into 2 groups: the first included 37 patients with excellent immediate results of treatment on the inverted Glasgow outcome scale (GOS 1), the second included 20 patients with moderate and severe disability (GOS 2-3).Results. The patients with moderate and severe disability as immediate results of treatment have a lower quality of life than patients with excellent results, due to the presence of severe headache, anxiety and depression disorders.Conclusion. The decline in the quality of life of patients with moderate and severe disability as immediate results of treatment of the cerebral aneurysms ruptures requires a rehabilitation therapy.
THE SPECTRUM OF BACTERIAL AGENTS ISOLATED FROM THE WOUND IN PATIENTS WITH DIABETIC FOOT SYNDROME IN ONE OF THE HOSPITALS IN CHELYABINSK
Authors: SHLEPOTINA N. M. , KOLESNIKOV O. L. , PLOTKIN L. L. , SHISHKOVA YU. S.
Published: July 2018

Aim. To establish the features of the spectrum and antibiotic resistance of bacterial agents isolated from wounds in patients with diabetic foot syndrome.Materials and methods. In 2016-2017 a retrospective cohort study was carried out on the basis of the archive of the municipal budgetary healthcare institution «City clinical hospital №6» in Chelyabinsk with analyzing the data of the medical cards of patients who were at the department of purulent surgery in 2015 with various forms of diabetic foot syndrome. The main data for the study were taken from the results of bacteriological studies. To determine the antibiotic susceptibility of the isolated flora, a diffusion method was used with discs with antibiotics. The classification proposed by Wagner F.W. was used to determine the prevalence and depth of the lesion of diabetic foot syndrome (1979). The statistical processing of data was carried out using Excel 12.0 (Office 2008), the level of significance of the results was evaluated by calculating the two-sided exact Fisher test (F) using the calculator on the site «Medical Statistics» (URL: http://medstatistic.ru/calculators/calchi.html).Results. In the studied group of patients with diabetic foot syndrome the infectious process caused by one bacterial agent was most often encountered. The most common causative agent isolated from the wound defects was S. aureus. The tendency to develop resistance against antibiotics, widely used in clinical practice, is more pronounced in representatives of gram-negative flora.Conclusion. The obtained data generally coincide with the results of studies in the field of the microbial spectrum of the wounds in diabetic foot syndrome determined by other authors, but the predominance of monoinfections over bacterial associations in this studied population requires further study.
APPROACHES TO EARLY DIAGNOSIS OF THYROID CANCER
Authors: ABDRASHITOVA A. T. , PANOVA Т. N. , DIAKOVA O. N. , DZHUVALAKOV S. G. , TYOPLYI D. L.
Published: July 2018

Aim. To analyze modern literature dealing with the issues of finding highly informative modern methods of early diagnostics of malignant tumors of thyroid.Materials and methods. The study of recent Russian and foreign literature in the databases RSCI, Scopus, Web of Science, Pubmed has been carried out.Results.This article represents statistical information on the prevalence of this disease, age and gender peculiarities, modern international cytological classification of thyroid – Thyroid Bethesda Classification. The article shows diagnostic values of ultrasound, elastography, dopplerography, as well as fine needle aspiration biopsy with the subsequent cytological, immunocytochemical study, and molecular-genetic research. The advantages and disadvantages of existing methods of diagnostics of cancer of thyroid have been analyzed. High sensitivity and specificity of molecular genetic studies, which increases with application of diagnostic panels has been observed.Conclusion. Modern science has many methods for early diagnosis of malignant forms of thyroid disease, but none of them meets the modern requirements of practical health care. It justifies the importance of further search for sensitive, specific and available diagnostic methods of thyroid cancer.
CLINICAL PSYCHIATRIC INTERVIEW (LECTURE)
Authors: KOSENKO V. G. , KRASILNIKOV G. T. , AGEEV M. I. , SHULKIN L. M. , KOSENKO N. A. , GRIDINA YU. V. , ZAKHAROVA-MAKAGON YA. A. , ISAEVA N. V.
Published: July 2018

Aim. To reflect the theoretical foundations and create a minimum set of practical skills of diagnostic and treatment interviewing in psychiatry.Materials and methods. To achieve this goal a thematic selection of scientific literature sources of both classical and modern domestic and foreign authors was carried out. In addition, the authors focused on the rich personal experience of interviewing, which allowed choosing and describing the most effective, practically significant methods and methods of clinical diagnosis in psychiatry in the form of psychiatric interviewing.Results. The factors that determine the nature and content of the interview: place, time, participants of the interview – doctor and patient have been described and analyzed. The analytical description of the main psychotechnologies which are used by the psychiatrist (psychotherapist) in the course of interview is given: establishment of contact, technology of hearing of and listening to the patient, technology of asking questions, technology of a pause and silence, technology of tactile contact, technology of using humour, advice, recommendation, interpretation, technology of finishing the interview and its structuring.Conclusion. Clinical interview is the main diagnostic and psychotherapeutic tool of a psychiatrist, and especially of a psychotherapist. The diagnostic effectiveness of a psychiatric interview is determined by the extent to which the information obtained in the course of it is structured into a diagnostic concept, the therapeutic effectiveness is determined by the extent to which the patient accepts the concept of understanding by the doctor of his painful condition (achieved compliance).
CLINICAL AND DIAGNOSTIC VALUE OF DETERMINATION OF NEOPTERIN IN ATOPIC DERMATITIS IN CHILDREN
Authors: BEN M. M. , YANCHEVSKAYA E. YU. , MESNYANKINA O. A.
Published: July 2018

Aim. To improve the diagnosis of allergic skin diseases in childrenMaterials and methods. 135 children aged from 2 to 6 with atopic dermatitis were examined during exacerbation. They were on inpatient treatment in the skin and venereologic department of the Regional skin and venereologic dispensary and the Department of Allergology of the Regional children's clinical hospital. At the same time, 103 people (the main group) had uncomplicated course of the disease, 32 patients had complications of atopic dermatitis in the form of secondary infection. The control group consisted of 29 children aged 2 to 6. Neopterin in serum was determined by enzyme-linked immunosorbent analysis using test kits "Neopterin ELISA" (Germany). Statistical reliability of the obtained data was evaluated using The Student's test.Results. Atopic dermatitis in children, regardless of clinical manifestations, is accompanied by an increase in the content of neopterin in serum. The nature of the increase in the level of neopterin is determined by the duration of the disease, while its highest values are characteristic of the prolonged course of the process (over 4 years).Conclusion. The determination of neopterin in children with atopic dermatitis is a promising laboratory method for assessing the severity of dermatosis, monitoring and forecasting the further course of the process, as well as evaluating the effectiveness of therapeutic measures.
CORRECTION OF HYPODINAMY AS A FACTOR OF THE RISK OF OBESITY DEVELOPMENT IN FIRE-RESCUERS
Authors: BURDYUKOVA E. V. , ARKHANGELSKAYA A. N. , ALEKSEENKO S. N. , YAKIREVICH I. A. , DMITRIEVA E. A. , KARAZHELYASKOV O. P. , IVKINA M. V. , GUREVICH K. G.
Published: July 2018

Aim. To evaluate the effectiveness of the developed special sports complex in the prevention of hypodynamia and obesity among firefighters-rescuers.Materials and methods. A survey of 490 men with no history of chronic infectious and non-infectious diseases aged 20-59 was conducted. 328 people were the main group, 162 people were the control group. The baseline data included anthropometric development indicators, bioimpedance test results, the extraction of biochemical blood test results; the body mass index (BMI) and the ratio of waist and hip circumference were determined. A questionnaire was conducted to identify hypodynamia (according to the IPAQ questionnaire) and the nutrition structure (according to the questionnaire on the food label literacy questionnaire, past). Both questionnaires were adapted to the Russian Federation. Statistica for Windows 8.0 was used for statistical processing. We used a comparison of the means of the Student method. To compare the values expressed in percent, the method of inverse trigonometric Fisher transformations was used.Results. We have developed and proposed for firefighters-rescuers, included in the main group, special sports complexes, which were used for 6 months. These complexes represent additional physical training by the developed method. There are two of them: one with an emphasis on the prevention and rehabilitation of people with osteochondrosis of the lumbar spine, and the other for cervical and thoracic localization, including with a syndrome of shoulder-scapular periarthritis.Classes were held 3 times a week, the duration of 1 session was 45-50 minutes. The choice of the complex was carried out at the request of firefighters-rescuers. The first complex was selected by 52 people. Based on the results of the study, against the background of the use of sports complexes, there was a 2-fold decrease in the incidence of obesity. Such a high efficiency is due to the fact that obesity of the I degree prevailed among the firefighters-rescuers. In addition, the frequency of occurrence of dyslipidemia, hyperglycemia, and hypodynamia decreased.Conclusion. The use of this sports complex can reduce the risk factors for development of disability among rescue firefighters by preventing hypodynamia and reducing the incidence of hyperglycemia and dyslipidemia, as factors in the development of obesity.
ANALYSIS OF MIXED COMBINATIONS OF MEDICINAL PRODUCTS BASED ON ABAKAVIR, LAMIVUDIN, ZIDOVUDIN USING THE METHOD OF MICROCOLONIES LIQUID CHROMATOGRAPHY
Authors: GONCHIKOVA YU. A. , CHMELEVSKAYA N. V. , ILLARIONOVA E. A.
Published: July 2018

Aim.To develop a technique for the detection and separation of abacavir, lamivudine, zidovudine, both individually and combined with adaptol, azaleptin, analgin, amitriptyline, haloperidol, melipramine, neuleptil, phenobarbital, fluoxetine, and chlorprotixen using high performance liquid chromatography (HPLC).Materials and methods. A column filled with ProntoSIL-120-5-C18 AQ was used, eluting with A [0.2 M lithium perchlorate − 0.005 M perchloric acid] − water (5: 95); eluent B is acetonitrile. Chromatography conditions: a linear gradient of the solvent is 3700 μl from 5 to 70% at a flow rate of 100 μl / min. The temperature of the column was 40°C. The results were processed with the help of the computer program MultiChrome (ZAO Ampersend, Moscow).Results. The method of separation and detection of combinations of abacavir, lamivudine, zidovudine with adaptol, azaleptin, analgin, amitriptyline, haloperidol, melipramine, neuleptil, phenobarbital, fluoxetine and chlorprotixene by reversed-phase high-performance liquid chromatography was developed.Conclusion. The developed technique allows detecting abacavir, zidovudine, lamivudine with the help of the HPLC method after isolation from urine separately or at combined poisonings with adaptolom, azaleptinom, dipyrone, amitriptilinom, galoperidolom, melipraminom, neuleptilom, phenobarbital, fluoxetine and hlorprotiksenom
CORRECTION OF CYTOKINE AND HORMONAL IMBALANCE IN THE TREATMENT OF ANGINA PECTORIS
Authors: GORDEEVA E. K. , KADE A. KH.
Published: July 2018

Aim. To evaluate the dynamics of cytokine status (IL-1ß, IL-4, IL-6, IL-10) and hormonal profile (cortisol, ACTH, β-endorphins) in patients with stable angina II-III functional class in the course of standard treatment and combined use of TES-therapy.Materials and methods. All patients were divided into 2 groups: 1st (n=30) therapy of angina according to the Protocol and 2nd (n=30) combined therapy of angina according to the Protocol and TES-therapy.Results. The results showed that normalization of the studied cytokines level in patients of the 1st group is not improved.In the 2nd group of patients statistically the levels of the studied cytokines was significantly decreasing (p≤0.01) and the levels of ACTH, cortisol and β-endorphin were significantly (p≤0.01) increasing.Conclusion. The obtained results suggest that TES-therapy conducted in the 2nd group of patients, contributes to the correction of cytokine imbalance and hormonal profile, which indicates the necessity of its inclusion in standard therapy of angina.
RADIOLOGICAL DIAGNOSTIC OF PLACENTA ACCRETE IN PREGNANT WOMEN WITH CESAREAN SCAR
Authors: POMORTSEV A. V. , KHUDOROZHKOVA E. D. , MATOSYAN M. A. , MAKUKHINA V. V. , NOSULYA I. G.
Published: July 2018

Aim. To define significant ultrasound and magnetic resonance imaging markers in diagnostics of the depth of chorion invasion in myometrium in pregnant women after Cesarean section was carried out.Materials and methods. 68 pregnant women from 28 to 32 gestation weeks with Caesarian scar and placenta on the front wall of uterus were retrospectively studied. Pregnant women were divided into 4 groups depending on histologic verification of placenta invasion depth. MRI and ultrasound assessment of the lower uterine segment was carried out and the most significant US and MRI markers of placenta accreta were distinguished. Subsequently, the received results of the research were processed by algorithms of factor analysis with calculation of informativeness of each marker and with determination of the forecast of placenta accreta.Results. As a result, group I of pregnant women scored within 0-0.9 conventional units, in group II – 1-3 conventional units, in group III – the score was 3.1-5.0 conventional units, in group IV – 5.1-7.0 conventional units. In groups III and IV are characterized by the fact of signs combination. In group III the combination of 2 signs was detected in 65% of cases, of 3 signs – in 25% of pregnant women.Conclusion. The most informative marker of ultrasound diagnostic of placenta accreta was determination of venous lacunas in its suprabasal part (0.42), in case of MRI it was the assessment of the bladder wall (0.45). The sensitivity and specificity of ultrasonography were 86.2% and 84.8%, in MRI they were 96% and 94.4% respectively.
CLASSROOM ACTION RESEARCH: PENERAPAN STRATEGI BELAJAR NOTE-TAKING, DISCUSSION, REFLECTIVE (NDR) UNTUK MENINGKATKAN HASIL BELAJAR MAHASISWA IPA
Authors: Sabtiawan Wahyu Budi
Published: July 2018

AbstractOne of the difficulties of science students is learning abstract topics, such as Topic of Atom, Ion, and Molecule. This study aims to solve the difficulty using a learning strategy of Note-Taking, Discussion, Reflective (NDR). Specifically, the purpose of this study is to implement the NDR strategy for increasing students' learning outcomes. The research design is classroom action research. Methods of data collection include observation, tests, and interviews. The results of the study indicate that the implementation of Note taking-Discussion-Reflective strategy can increase the learning outcomes through the implementation of 2 research cycles where in each cycle there are three stages, namely, planning, action, and reflection. The average scores increased from cycle 1 to cycle 2 by 4.2% and a minimum score of completeness of 75 has been achieved in cycle 2. The implementation of learning was at a good and excellent level during cycles 1 and 2. In addition, there were four student's positive response to the implementation of NDR strategy, that is related to discussion activities, note-taking, learning opportunities, and working in groups.Keywords: classroom action research, NDR strategy, learning outcome.