bluuebunny/crossref_metadata_2025 huggingface dataset:
Association between neurofibromatosis type 1 and cerebrovascular diseases in children: A systematic review
Authors: Barreto-Duarte Beatriz , Andrade-Gomes Fabiana H. , Arriaga María B. , Araújo-Pereira Mariana , Cubillos-Angulo Juan Manuel , Andrade Bruno B.
Published: January 2021

Background

Neurofibromatosis type 1 (NF-1) is an autosomal dominant disease that affects one in every 3000 individuals. This disease can present a wide range of clinical manifestations, ranging from skin abnormalities to severe vascular damage. Although not commonly recognized in the context of NF-1, cerebrovascular disease (CVD), can be often present since childhood and diagnosed just later in life. When present, NF-1-associated CVD clinical manifestations may include headache, cognitive deficits and ultimately aneurysm rupture, causing death. Thus, CVD plays an important role in the clinical manifestations, disease severity and prognosis of patients with NF-1. This systematic review aims to summarize the body of evidence linking NF-1 and CVD in children.

Methods

Two independent investigators performed a systematic review on the PubMed and EMBASE search platforms, using the following key terms: “neurofibromatosis type 1”, “Von Recklinghausen’s disease”, "children", "adolescents", "stroke", "Moyamoya disease", "vascular diseases", "cerebrovascular disorders", "aneurysm" and "congenital abnormalities". Studies focused on assessing the development of CVD in children with NF-1 were included.

Results

Seven studies met the inclusion criteria. Twelve different clinical manifestations have been associated with cerebrovascular changes in children with NF-1; 44,5% of diagnosed patients were asymptomatic.

Conclusion

The available evidence suggests that CVDs are related with the progression of NF-1, even in the absence of a clear clinical manifestation. In addition, improved prognosis was observed when imaging tests were performed to screen for cerebrovascular alterations early during the clinical investigation. Early diagnosis of CVD in NF-1 patients foster implementation of timely interventions, directly impacting clinical outcomes.
Clustering of lifestyle risk factors among adult population in India: A cross-sectional analysis from 2005 to 2016
Authors: Shaikh Rufi , Khan Junaid
Published: January 2021

Introduction

Individual’s early life style and health behaviors are directly linked to chronic non-communicable diseases. Considering the increased burden of NCDs during the last two decades, the aim of this study is to assess co-occurrence/clustering of lifestyle risk factors and its association with different socio-demographic and economic characteristics among adult men and women in India from 2005–2016.

Methods

This study utilized the data from the National Family Health Survey 2005–06 and 2015–16 survey rounds. Multinomial logistic regression is employed to evaluate co-occurrence of multiple risk factors among adult men and women of different socio-economic and demographic characteristics to identify the subgroups with elevated risk of clustering of multiple unhealthy lifestyle risk factors.

Results

More adult men in India tend to exhibit clustering of multiple non-communicable disease risk factors than females. Individuals between 30–49 years of age, residing in urban areas, the population with no education, separated couples and those from poor economic strata are the specific population subgroups show higher prevalence of co-occurrence of multiple risk factors. The regional pattern of clustering of risk factors shows that the prevalence of co-occurrence of multiple risk factors is higher among men and women from the North-Eastern part of India compared to the other regions of the country.

Conclusion

The prevalence of clustering of multiple risk factors associated with chronic NCDs is substantially high and has increased between 2005–06 to 2015–16. India may therefore experience a significant increase in the burden of chronic non-communicable diseases in the coming years. We therefore conclude that appropriate strategies should be implemented by policy makers and the government to reduce the overall health burden of NCDs due to lifestyle habits.
Integrating morphology and metagenomics to understand taxonomic variability of Amphisorus (Foraminifera, Miliolida) from Western Australia and Indonesia
Authors: Macher Jan-Niklas , Prazeres Martina , Taudien Sarah , Jompa Jamaluddin , Sadekov Aleksey , Renema Willem
Published: January 2021

Foraminifera are a group of mostly marine protists with high taxonomic diversity. Species identification is often complex, as both morphological and molecular approaches can be challenging due to a lack of unique characters and reference sequences. An integrative approach combining state of the art morphological and molecular tools is therefore promising. In this study, we analysed large benthic Foraminifera of the genus Amphisorus from Western Australia and Indonesia. Based on previous findings on high morphological variability observed in the Soritidae and the discontinuous distribution of Amphisorus along the coast of western Australia, we expected to find multiple morphologically and genetically unique Amphisorus types. In order to gain detailed insights into the diversity of Amphisorus, we applied micro CT scanning and shotgun metagenomic sequencing. We identified four distinct morphotypes of Amphisorus, two each in Australia and Indonesia, and showed that each morphotype is a distinct genotype. Furthermore, metagenomics revealed the presence of three dinoflagellate symbiont clades. The most common symbiont was Fugacium Fr5, and we could show that its genotypes were mostly specific to Amphisorus morphotypes. Finally, we assembled the microbial taxa associated with the two Western Australian morphotypes, and analysed their microbial community composition. Even though each Amphisorus morphotype harboured distinct bacterial communities, sampling location had a stronger influence on bacterial community composition, and we infer that the prokaryotic community is primarily shaped by the microhabitat rather than host identity. The integrated approach combining analyses of host morphology and genetics, dinoflagellate symbionts, and associated microbes leads to the conclusion that we identified distinct, yet undescribed taxa of Amphisorus. We argue that the combination of morphological and molecular methods provides unprecedented insights into the diversity of foraminifera, which paves the way for a deeper understanding of their biodiversity, and facilitates future taxonomic and ecological work.
Dynamic aspiration based on Win-Stay-Lose-Learn rule in spatial prisoner’s dilemma game
Authors: Shi Zhenyu , Wei Wei , Feng Xiangnan , Li Xing , Zheng Zhiming
Published: January 2021

Prisoner’s dilemma game is the most commonly used model of spatial evolutionary game which is considered as a paradigm to portray competition among selfish individuals. In recent years, Win-Stay-Lose-Learn, a strategy updating rule base on aspiration, has been proved to be an effective model to promote cooperation in spatial prisoner’s dilemma game, which leads aspiration to receive lots of attention. In this paper, according to Expected Value Theory and Achievement Motivation Theory, we propose a dynamic aspiration model based on Win-Stay-Lose-Learn rule in which individual’s aspiration is inspired by its payoff. It is found that dynamic aspiration has a significant impact on the evolution process, and different initial aspirations lead to different results, which are called Stable Coexistence under Low Aspiration, Dependent Coexistence under Moderate aspiration and Defection Explosion under High Aspiration respectively. Furthermore, a deep analysis is performed on the local structures which cause defectors’ re-expansion, the concept of END- and EXP-periods are used to justify the mechanism of network reciprocity in view of time-evolution, typical feature nodes for defectors’ re-expansion called Infectors, Infected nodes and High-risk cooperators respectively are found. Compared to fixed aspiration model, dynamic aspiration introduces a more satisfactory explanation on population evolution laws and can promote deeper comprehension for the principle of prisoner’s dilemma.
Effectiveness of surgery and hyperbaric oxygen for antiresorptive agent-related osteonecrosis of the jaw: A subgroup analysis by disease stage
Authors: Watanabe Takuma , Asai Keita , Fukuhara Shizuko , Uozumi Ryuji , Bessho Kazuhisa
Published: January 2021

Antiresorptive agent-related osteonecrosis of the jaw (ARONJ) is an adverse event induced by antiresorptive agents (ARAs). The purpose of this study was to evaluate variables, mainly surgery and hyperbaric oxygen (HBO) therapy, associated with treatment outcomes in patients with a diagnosis of ARONJ at a single center. We enrolled consecutive patients who presented to our hospital for the management of stage 2 or 3 ARONJ between January 2003 and December 2019. The relationship between potentially predictive factors and outcome variables was examined using statistical analyses, along with a subgroup analysis based on disease stage. Of 252 patients included in this study, 206 had stage 2 ARONJ and 46 had stage 3 ARONJ. There were 119 patients with osteoporosis and 133 with malignant disease. In total, 139 patients were healed, and the healing rate of patients with stage 3 ARONJ was lower than that of patients with stage 2 ARONJ. With regard to the combination of surgery and HBO therapy, most patients underwent HBO before and after surgery. In the univariable analysis, surgery showed a therapeutic effect in both stage 2 and 3 ARONJ, whereas HBO showed a therapeutic effect in stage 2 ARONJ. In the multivariable analysis for stage 2 ARONJ, extensive surgery showed a stronger association with healing than conservative surgery, whereas ≥46 sessions of HBO therapy was less associated with healing than was non-HBO therapy. Our findings suggest that extensive surgery is highly effective against ARONJ regardless of disease stage if there is a sequestrum separation and systemic tolerance, whereas HBO therapy before and after surgical approach can be effective. Further studies are needed to identify treatment strategies for patients with treatment-refractory ARONJ who may be forced to undergo long-term HBO therapy with the expectation of sequestrum separation.
Expression pattern determines regulatory logic
Authors: Mora-Martinez Carlos
Published: January 2021

Large amounts of effort have been invested in trying to understand how a single genome is able to specify the identity of hundreds of cell types. Inspired by some aspects ofCaenorhabditis elegansbiology, we implemented an in silico evolutionary strategy to produce gene regulatory networks (GRNs) that drive cell-specific gene expression patterns, mimicking the process of terminal cell differentiation. Dynamics of the gene regulatory networks are governed by a thermodynamic model of gene expression, which uses DNA sequences and transcription factor degenerate position weight matrixes as input. In a version of the model, we included chromatin accessibility. Experimentally, it has been determined that cell-specific and broadly expressed genes are regulated differently. In our in silico evolved GRNs, broadly expressed genes are regulated very redundantly and the architecture of their cis-regulatory modules is different, in accordance to what has been found inC.elegansand also in other systems. Finally, we found differences in topological positions in GRNs between these two classes of genes, which help to explain why broadly expressed genes are so resilient to mutations. Overall, our results offer an explanatory hypothesis on why broadly expressed genes are regulated so redundantly compared to cell-specific genes, which can be extrapolated to phenomena such as ChIP-seq HOT regions.
Seroprevalence and risk factors associated with exposure to Leishmania infantum in dogs, in an endemic Mediterranean region
Authors: Rombolà Pasquale , Barlozzari Giulia , Carvelli Andrea , Scarpulla Manuela , Iacoponi Francesca , Macrì Gladia
Published: January 2021

Canine leishmaniasis (CanL) is a zoonotic parasitic disease caused by Leishmania infantum in the Mediterranean area and transmitted by phlebotomine sand fly vectors. The domestic dog is the main reservoir host. The aim of this study was to assess the influence of different individual, environmental and spatial risk factors on the dog exposure to L. infantum and to estimate the seroprevalence among owned and kennel dogs, in the Lazio region (central Italy), where canine leishmaniasis is endemic. In the period 2010–2014, 13,292 sera from kennel and owned dogs were collected by official and private veterinarians. The presence of anti-Leishmania IgG was analysed by indirect fluorescent antibody test (IFAT), using a 1:80 titre cut-off. At the univariable analysis, CanL seropositivity was associated with sex, size, breed, coat length, living with other dogs and forest/semi-natural land cover. At the multivariable analysis, age, ownership and attitude were confirmed as risk factors, being more than 2 years old, owned, and hunting dogs at higher risk. Being a Maremma sheepdog was a protective factor. A true overall seroprevalence of 6.7% (95% CI: 6.2–7.2) was estimated in the whole population while 7.3% (95% CI: 6.8–7.8) was estimated in kennel dogs and 74.3% (95% CI: 70.8–77.6) in owned dogs. The role of kennels as a key component for CanL active and passive surveillance was also highlighted. This study confirmed the endemicity of CanL in the Lazio region and focused some factors that can influence the seropositivity of dogs in a Mediterranean region.
Co-Benefits der globalen Energiewende
Authors: Sperfeld Franziska , Helgenberger Sebastian
Published: January 2021

Anhand von 17 Länderstudien zu sozialen und wirtschaftlichen Chancen erneuerbarer Energien wurden neue politische Gestaltungsoptionen entwickelt. Diese können länderspezifisch realisiert werden und damit auch zur wirtschaftlichen Bewältigung der Covid-19-Pandemie beitragen.
Lehren einer Pandemie für die Krisenvor- und -nachbereitung
Authors: Rudolph Frederic
Published: January 2021

Umweltschutz und Pandemie-Schutz haben als Handlungsfelder urbaner Politik scheinbar wenig miteinander zu tun. Es zeigt sich jedoch, dass die Folgen der Pandemie große Potenziale für erfolgreichen urbanen Umweltschutz bergen und umgekehrt, dass dieser die Resilienz der Städte fördert.
THE REVIEW OF TRANSLINGUAL WORDS. AN EAST ASIAN LEXICAL ENCOUNTER WITH ENGLISH BY JIEUN KIAER, 2019. ROUTLEDGE LONDON AND NEW YORK, ISBN: 978-1-351-10947-5.
Authors: WOJTASIK-DZIEKAN Emilia
Published: January 2021

THE REVIEW OF TRANSLINGUAL WORDS. AN EAST ASIAN LEXICAL ENCOUNTER WITH ENGLISH BY JIEUN KIAER, 2019. ROUTLEDGE LONDON AND NEW YORK, ISBN: 978-1-351-10947-5.
ABORDAGEM SOBRE METODOLOGIA DA PESQUISA CIENTÍFICA NAS REDES SOCIAIS: RELATO DE UMA EXPERIÊNCIA EXTENSIONISTA
Authors: Moreira Luana Viviam , Souza Marina Rocha Fonseca , Gonçalves Moisés Willian Aparecido , Galvão Endi Lanza
Published: January 2021

O uso das mídias sociais cada vez mais pode ser um importante aliado no processo de aprendizagem. Neste contexto, este projeto extensionista tem como objetivos: 1) difundir o conhecimento sobre metodologia da pesquisa científica para alunos de graduação, pós-graduação e população em geral interessada nesta temática, por meio da rede social Instagram; 2) disponibilizar informações técnicas confiáveis para guiar a realização de pesquisas científicas; 3) promover conteúdo didático baseado em literatura de referência para complementar o processo de aprendizagem. As atividades do projeto iniciaram-se à partir da idealização e criação do perfil @pesquisasimplificada no Instagram, com a utilização de recursos autorais de imagens, gráficos, áudios e vídeos para compartilhamento de conteúdo relacionado ao desenvolvimento de pesquisas e publicações científicas no meio acadêmico. A página foi criada em junho de 2020, e possui atualmente 1171 usuários seguidores com expressivo engajamento, reconhecido pela interação entre usuários e administradores da página. O desenvolvimento deste projeto extensionista, iniciado oportunamente num momento em que as instituições tiveram que encontrar formas de garantir a oferta do ensino através de novos métodos, representa a garantia do acesso a conteúdos acadêmicos e informações confiáveis no ambiente virtual, como forma de superar as barreiras impostas pelo isolamento social, requeridos para o controle da COVID-19.
POSSIBILIDADES EM UM PROJETO DE EXTENSÃO DE APOIO AO PROGRAMA SAÚDE NA ESCOLA FRENTE AO CONTEXTO DA COVID-19
Authors: Castro Renata , Von Muhlen Luiza Seffrin , Carvalho Renata Sousa , Wanghon Zuila Maria Lobato
Published: January 2021

Em poucos meses desde o relato do primeiro caso da COVID-19 na China, o mundo está em alerta. No Brasil foi atingida a triste marca de 135.793 mortos e 4.495.183 acometidos pela COVID-19. Esse contexto atingiu profundamente a sociedade, impondo novas formas de nos relacionarmos. Na vida universitária não tem sido diferente. O desenvolvimento das ações de extensão tem sido resultado de criatividade aliada a necessidade de continuar contribuindo com a sociedade. Este artigo relata o percurso de um projeto de extensão durante os primeiros meses da epidemia na cidade de Florianópolis. O Projeto de extensão tem como objetivo potencializar as ações do PSE nos municípios parceiros. Com a suspensão das atividades presenciais de ensino no estado surgiu a necessidade de repensar as ações a partir de novas estratégias. Uma das primeiras estratégias foi a formação da equipe para o desenvolvimento de materiais educativos em saúde utilizando como veículo as redes sociais. Uma segunda frente foi apoiar a gestão de municípios para a reorganização da atenção em saúde bucal, levando em consideração as recomendações das instituições mundiais de saúde, as normas técnicas vigentes em nosso país, bem como as melhores evidências científicas. Por fim, iniciou-se juntamente aos municípios o planejamento de ações possíveis no âmbito do PSE, levando em consideração os diferentes contextos e buscando a continuidade das ações de promoção e de educação em saúde.
DESCAMINHOS DA PRÁTICA PEDAGÓGICA DECOLONIAL: AS DIFICULDADES DE DESCOLONIZAR A CONFECÇÃO DO CONHECIMENTO A DISTÂNCIA
Authors: Mantelli Gabriel Antonio Silveira , Passoni Chiara Mori , Belau Lahanna Kathilla Alves dos Santos
Published: January 2021

O momento de pandemia da COVID-19 trouxe, em 2020, diversas dificuldades para a prática da extensão universitária. Principalmente àqueles que buscam contornar a pedagogia comum e industrial, seguindo os passos da pedagogia de resistência de base decolonial. A distância física implicou na necessidade de escolhas no que tange à metodologia dos encontros e da confecção do conhecimento. Se antes do distanciamento social, o conhecimento científico já era pautado por padrões da modernidade/colonialidade, nesse período atípico, essas relações apenas se intensificaram. Assim, se questiona quais são as dificuldades da manutenção de um ensino crítico e de uma confecção do conhecimento participativa e inclusiva mesmo que dificultada pela distância. No presente texto, a Roda de Estudos Decoloniais, fruto de uma parceria interinstitucional da Fundação Getulio Vargas de São Paulo (FGV-SP) com a Universidade São Judas Tadeu (USJT), e a Clínica de Direitos Humanos Socioambientais da USJT são utilizadas como casos de estudo e reflexão para entender as vantagens da extensão universitária durante a pandemia, bem como, a quebra de paradigmas coloniais e rupturas de ações da modernidade que antes desse momento passavam despercebidas nas vísceras dos extensionistas e docentes.
PROJETO DE EXTENSÃO “AVALIAÇÃO DA COLONIZAÇÃO PELO ESTREPTOCOCO DO GRUPO B EM GESTANTES”: INOVAÇÃO DIANTE DE UM CENÁRIO PANDÊMICO
Authors: Fabião Cristina Damé , Brandelli Taiane Marini , De Mansur Augusto Homem Carvalho , Goulart Yasmin Boa Hora , Cabreira Julia Arriada , Salvador Bruna Frizzo
Published: January 2021

Em virtude das barreiras impostas pela pandemia do COVID-19 durante o ano de 2020, novos hábitos foram adquiridos baseados nas medidas de isolamento social. Esse cenário, refletido também no meio científico, compeliu a reinvenção das ações extensionistas nesse período. Com isso em mente, o projeto de extensão denominado “Avaliação da colonização pelo Estreptococo do Grupo B em gestantes atendidas em ambulatório de pré-natal da UCPel”, no intuito de respeitar o distanciamento necessário ao momento e manter o compromisso da universidade com a sociedade, precisou criar alternativas de funcionamento. As mídias sociais de comunicação, fortes fontes de transmissão de informação, tornaram-se positivos contribuintes para a saúde coletiva. A realização de videoconferências para reunir e capacitar os membros do projeto, assim como o desenvolvimento de um perfil no Instagram, intitulado Gestar Bem UCPel foram planejados com o objetivo de levar informação e conhecimento para os acadêmicos e profissionais da área e, principalmente, para as gestantes. Esse relato de experiência trata-se de apresentar a dinamização das atividades e formas de atuação do projeto frente aos empecilhos vivenciados devido a pandemia do COVID-19.
AÇÕES EXTENSIONISTAS EM DERMATOLOGIA VETERINÁRIA: PROMOÇÃO DE SAÚDE E BEM-ESTAR EM TEMPOS DE ISOLAMENTO SOCIAL
Authors: Rosa Cristiano Silva da , Silva Edgar Cleiton da , Grala Caroline Xavier , Bilhalva Maurício Andrade , Alves Caroline Castagnara , Andrade Junior Antônio Gonçalves
Published: January 2021

O projeto de extensão intitulado “Dermatovet: Serviço em dermatologia veterinária, na área de abrangência da UFPel” (DermatoVet UFPel), teve início no primeiro semestre de 2018 e surgiu como uma necessidade atual na medicina veterinária, tendo em vista que as especialidades estão em ascensão. O projeto visa realizar atendimento especializado em dermatologia veterinária para a comunidade que utiliza os serviços do Hospital de Clínicas Veterinária da UFPEL (HCV/UFPel). Dessa forma, o objetivo do trabalho foi descrever as atividades do projeto DermatoVet UFPel, expondo as mudanças necessárias para se manter o trabalho extensionista em momentos de isolamento social. As atividades de extensão promovidas pelo grupo, envolviam o atendimento semanal especializado em dermatologia para a comunidade externa. Com a suspensão de atividades acadêmicas, as ações de extensão se transformaram, passando a utilizar as mídias sociais do projeto. De abril de 2018 até agosto de 2019 haviam sido realizados um total de quarenta e seis atendimentos clínicos, sendo de quarenta e três cães e três gatos. O Instagram do projeto possui 787 seguidores e no Facebook 135 curtidas, ambas em crescimento constante. A primeira publicação deste novo período, obteve um alcance de 262 pessoas no Instagram e vinte e três no Facebook. Em contraste, a última publicação alcançou 620 pessoas no Instagram e 108 no Facebook, demonstrando o engajamento das páginas, e indicando que o conteúdo está alcançando um maior público. Em nossos resultados parciais, podemos observar o crescimento de nossas redes sociais, refletindo em informações mais disseminadas e que consequentemente levarão a maior instrução aos tutores de cães e gatos.
O PROJETO DE EXTENSÃO “COMUNICACÃO VOCAL DOS PORTADORES DE PARKINSON” EM TEMPOS DE PANDEMIA DA COVID-19
Authors: Rolim Maria Rita Pimenta , Freitas Maria Isabel D’Ávila , Ferreira Vargas Sandra Mendes , Eugênio Morgana , Haefliger Geremia Pedro Henrique , Costa Juliana Do Espírito Santo
Published: January 2021

Este ensaio descreve a importância da atuação da Fonoaudiologia no atendimento aos portadores da doença de Parkinson, e relata a experiência de um grupo de acadêmicos do curso de graduação em Fonoaudiologia da Universidade Federal de Santa Catariana (UFSC) no atendimento prestado a pacientes acometidos pela doença. A atuação desses acadêmicos se dá por meio do Projeto de Extensão Universitária denominado “Comunicação Vocal dos portadores de Parkinson”, que teve início em 2010 e segue até os dias atuais. O projeto está sob a responsabilidade do departamento de Fonoaudiologia da UFSC, onde é prestada assistência fonoaudiológica especializada a um grupo de portadores da doença de Parkinson. Com a crise provocada pela Covid-19, as atividades que vinham sendo realizadas semanalmente sofreram repentina paralização e, paulatinamente, vêm sendo retomadas de forma remota. Para tanto, a tecnologia tem sido a ferramenta que possibilita esse contato à distância, entretanto, tem se constituído um desafio para ambas as partes – profissionais e pacientes.
Electric current transformation by anisotropic electrically conductive medium
Authors: Аshcheulov А. А. , Derevianchuk M. Ya. , Lavreniuk D. А. , Romaniuk I. S.
Published: January 2021

The authors consider the aspects of electric current distribution in electrically conductive anisotropic medium and establish how geometrical factors affect its longitudinal and transverse components. In the case of an a×b×с rectangular plate, its selected crystallographic axes are located on the plane of the side face a×b, whereas one of these axes is oriented at an angle α to the edge a. Applying a certain potential difference to the upper and lower end faces of the plate causes the appearance of longitudinal and transverse components of the internal electric current. The paper demonstrates the possibility of transforming the magnitude of the electric current and a way to optimize this magnitude. The transformation coefficient of such a device is determined by the anisotropy of the electrical conductivity of the plate and the coefficient of its shape k = a/b. The authors consider a few versions of anisotropic dielectric transformer design and offer their equivalent electric circuits. Another suggested transformer design is spiral in shape, compact and is characterized by high transformation coefficient value n. For example, at external radius r1 = 12,5 mm, internal radius r2 = 2 mm, height b = 2 mm and plate thickness c = 2,0 mm, its transformation coefficient n = 103. The information is given on existing monocrystalline and artificial anisotropic materials that can be used for the proposed device. High-temperature superconducting materials characterized by a high value of residual resistance anisotropy hold special promise in this case. Using the described transformation effect will significantly expand the possibilities of practical application of the considered electroohmic phenomenon. This will lead to the emergence of a new generation of devices for microwave technology, electronics and power engineering.
Electronic devices for studying mechanical properties of biological tissues
Authors: Dubko A. G. , Osipov R. S. , Bondarenko Yu. V. , Bondarenko O. F.
Published: January 2021

The paper shows the relevance of studying the mechanical properties of biological tissues and biocompatible materials for solving the problems of general and reconstructive surgery, transplantology, manual therapy, virtual simulation of surgical operations, robotic surgery, etc. The authors present basic information about biological tissue as an object of research and give a brief overview of the devices used for studying the mechanical characteristics of biological tissues. An experimental system for testing deformations of biological tissues and biocompatible materials during compression is described. The system is developed using modern hardware and software, as well as effective technical solutions. The results of the practical use of the developed device are presented and the obtained dependences of the mechanical stress of biological tissue samples on their deformation under pressure are analyzed. The system has high metrological characteristics and low cost, and allows performing all the necessary functions for measuring, processing and visualizing the data. The measurements obtained with this system can help form the recommendations for doctors on choosing the optimal operation mode of medical devices and instruments in each specific case. In addition, the measured data can be used to create mathematical models of biological tissues and biocompatible materials in order to further carry out virtual experiments. In further studies, the authors plan to create the mathematical models of biological tissues based on the finite element method and using the actual values characterizing the tissue, obtained with the developed system.
KEEFEKTIFAN MODEL TIME TOKEN BERBANTUAN FLASHCARD TERHADAP HASIL BELAJAR PPKn KELAS II
Authors: Manunggal Duta Prima
Published: January 2021

Abstrak

Penelitian ini bertujuan untuk mendeskripsikan hasil belajar dalam pembelajaran PPKn denganmenggunakan model time token berbantuan media flashcard dan model direct instruction berbantuanmedia gambar di kelas II SD Gugus Piere Tendean dan untuk menguji keefektifan model time tokenberbantuan media flashcard daripada model direct instruction berbantuan media gambar terhadap hasilbelajar PPKn materi keberagaman karakteristik individu di sekolah kelas II SD Gugus Piere TendeanKaliwungu Kendal. Penelitian ini menggunakan metode kuantitatif jenis penelitian yang digunakanialah eksperimen dan desain nonequivalent control group design. Teknik sampel yang digunakan adalahcluster random sampling, dengan sampel sebanyak 51 siswa. Pengumpulan data menggunakan tes,observasi dan dokumentasi. Hasil uji hipotesis menunjukkan bahwa nilai thitung = 3,132, dan ttabel =2,010, karena thitung Ëƒ ttabel (3,132 Ëƒ 2,010) yang berarti model time token berbantuan media flashcardefektif digunakan pada pembelajaran PPKn kelas II SD. Hasil uji n-gain kelas eksperimen lebih tinggiyaitu nilai n-gain kelas kontrol adalah 0,293970401 tergolong kriteria rendah dan nilai n-gain kelaseksperimen adalah 0,39691064 tergolong kriteria sedang. Simpulan penelitian ini yaitu modelpembelajaran time token berbantuan media flashcard efektif digunakan pada pembelajaran PPKn siswakelas II SD Gugus Piere Tendean Kaliwungu Kendal.

This study aims to describe the learning outcomes in learning civic education by using a time tokenmodel assisted by flashcard media and direct instruction model assisted by image media in 2nd gradeSD Piere Tendean Cluster and to test the effectiveness of the time token model assisted by aflashcard media a picture of the learning outcomes of the civic education material on the diversity ofindividual characteristics in 2nd grade Primary Schools in the Piere Tendean Kaliwungu Kendalcluster. This research uses quantitative methods, the type of research used is experimental andnonequivalent control group design. The sampling technique used was cluster random sampling,with a sample of 51 students. Data collection uses tests, observations and documentation.Hypothesis test results show that the value of t-count = 3.132, and t-table = 2.010, because t-count Ëƒt-table (3.132 Ëƒ 2.010), which means that the time token model assisted by flashcard media iseffectively used in learning the civic education 2nd grade SD. The n-gain test results of theexperimental class were higher namely, the value of the n-gain of the control class was 0.293970401,classified as a low criterion and the n-gain value of the experimental class was 0.39691064, classifiedas a medium criterion. This research concludes that the time token learning model assisted byflashcard media is effectively used in learning civic education for 2nd-grade students of the PrimarySchool in the Kaliwungu Kendal Group.
УМОВИ ТРАНСФОРМАЦІЇ ІННОВАЦІЙНОГО ПІДПРИЄМНИЦТВА НА ФАКТОР РЕГІОНАЛЬНОГО ПОТЕНЦІАЛУ СТРАТЕГІЧНОЇ КОНКУРЕНТОСПРОМОЖНОСТІ
Authors: Варцаба В.І. , Гудзовата Л.М. , Завадяк Я.С.
Published: January 2021

Стаття присвячена умовам перетворення регіональної економіки на конкурентну територіальну систему на засадах інтенсифікації інноваційної активності. Метою дослідження є огляд світового досвіду трансформації інноваційної діяльності на конкурентну регіональну перевагу, що дозволить визначити умови, за наявності яких інноваційне підприємництво набуває форми та змісту визначального фактору  потенціалу територіальної конкурентоспроможності.

В процесі дослідження застосовані методи: категоріального аналізу при окресленні сутності поняття регіональної життєздатності, наукової абстракції при відстеженні закономірностей у формуванні регіональної конкурентоспроможності, каузальної індукції при виявленні причин та наслідків дії окремих факторів на рівень інноваційної активності в регіоні та ін.

Запропоновано визначення регіональної життєдіяльності як сукупності зусиль територіальної влади, бізнесу, що функціонує в області, соціуму регіону, інших регіональних акторів здійснювати діяльність, підвищувати потенціал розвитку та розбудовувати регіональну стратегічну конкурентоспроможність.

Висвітлено досвід Кремнієвої долини (США) у формуванні регіональної конкурентоспроможності. Побудовано трикутник умов перетворення інноваційного підприємництва на фактор конкурентоспроможності, в межах якого першою умовою визначена управлінська, яка являє собою конвергенцію регіональних та ділових інтересів. Другою – наявність людського потенціалу, здатного працювати в високотехнологічних компаніях. Третя умова – створення полінаціональної культури, яка служить «бульйоном» генерування нових ідей та способів їх імплементації.

Практична імплементація сформованих умов дозволяє територіальним органам влади розробити адекватну регіональну стратегію та задіяти інноваційну складову  для збільшення потенціалу конкурентоспроможності регіону.
ЗРУШЕННЯ У ГЛОБАЛЬНОМУ ОСВІТНЬОМУ ПРОСТОРІ В СУЧАСНИХ УМОВАХ (РЕГІОНАЛЬНИЙ ТА НАЦІОНАЛЬНИЙ ВИМІРИ)
Authors: Зайковський О.С.
Published: January 2021

Стаття присвячена дослідженню сучасних глобальних процесів, які суттєво впливають на трансформацію у системі вищої освіти. Інтернаціоналізація стала не тільки невід'ємною частиною безперервного процесу змін у вищій освіті, фактично процеси інтернаціоналізації вищої освіти стали важливою детермінантою розвитку та реформування вищої школи. В умовах глобальних трансформацій сучасного світу міжнародна співпраця стала важливим показником розвитку освіти, а самі університети стають глобальними установами, вплив яких на формування конкурентних переваг національної соціально-економічної системи постійно посилюється.

Оскільки в умовах інтернаціоналізації вищої освіти докорінно змінюється місце та роль університетів, існує потреба дослідження та виявлення відповідних тенденцій, що враховують трансформації, що відбуваються на національному, регіональному та глобальному рівнях і які матимуть відповідний вплив на подальший розвиток процесів інтернаціоналізації вищої освіти у майбутньому, що визначило мету наукової статті.

Для досягнення мети використано загальнонаукові та спеціальні методи дослідження, а саме: методи аналізу, абстрагування та синтезу (при дослідженні тенденцій, що враховують як внутрішні трансформації, так і глобальні зміни, і які визначають розвиток вищої освіти); методи класифікації та системного узагальнення (для систематизації  структурних трансформацій, що відбуваються на освітніх послуг); статистичні методи (для кількісної оцінки трансформацій, що відбуваються у глобальному освітньому просторі  в сучасних умовах).

Доведено, що врахування змін, що відбуваються у вищій освіті, передбачають розширений розвиток міжнародних науково-дослідницьких та освітніх програм і проектів, створення розгалуженої мережі між університетської співпраці одночасно із урахуванням та збереженням кращих національних традицій і культурних цінностей.
АНАЛІЗ РОЛІ АГРОПРОМИСЛОВОГО КОМПЛЕКСУ В ЕКОНОМІЦІ КРАЇНИ: ВНУТРІШНІЙ РОЗВИТОК ТА ЗОВНІШНЯ ТОРГІВЛЯ
Authors: Титарчук І.М.
Published: January 2021

Розглянуто основні макроекономічні тенденції, що впливають на сектор, роль ВВП сформованого у сільському, лісовому та рибному господарстві, особливості державного та приватного секторів у сільському господарстві, проаналізовано внутрішній розвиток агропромислового сектору по регіонах та в розрізі країни, а також стан зовнішньої торгівлі та перспективи експорту. Особливу увагу приділено державній підтримці аграрного напрямку через бюджетне фінансування програм та темпи її зростання. З точки зору концептуального підходу та узгодженої методології, стаття описує існуючі стратегічні та політичні пріоритети у агропромисловому комплексі, його основні досягнення та значення. Огляд є ретроспективним поглядом, спрямованим на те, щоб здійснити аналіз з достатньою точністю та вибіркою за п’ять останніх років. Для поглиблення розуміння ситуації використовувались існуючі спеціальні дослідження сектору та офіційні матеріали статистичних органів та державних організацій. На їх основні здійснювався аналіз тенденцій і змін ролі агропромислового комплексу в економіці країни. Також, шляхом опитування, визначено основні перешкоди з якими стикаються малі та середні підприємства аграрного сектору при виході на експортні ринки. Відповідно до отриманих результатів сформовано практичні поради для аграрних підприємств, державних органів влади та інституційних організацій підтримки розвитку бізнесу, що включають як нові рекомендації, що базуються на зарубіжному досвіді, так і удосконалений механізм реалізації уже відомих інструментів. Зокрема, визначено, що основними зонами втручання державних та приватних інституцій у розвиток агропромислового комплексу повинні стати підтримка здійснення експортних операцій (в т.ч. їх здешевлення) та розвиток інфраструктури підтримки експорту (в т.ч. регіональної). Також запропоновано проведення більш системного підходу до встановлення пріоритетів витрат разом із підвищеною передбачуваністю фінансування, це сприятиме тому, що державна підтримка стане більш ефективним рушієм для сталого розвитку агропромислового комплексу та зростання ВВП.
(Re)Discovering Story and Voice: The Adaptive Community Theatre Project
Authors: Horn Elizabeth Brendel , Boyd Belinda C. , Shero Megan
Published: January 2021

The Adaptive Community Theatre Project (ACTP) at the University of Central Florida (UCF) served to honor the voices and stories of community members with aphasia and other acquired neurocognitive disabilities, while combatting the isolation and depression often felt by this demographic. This paper will explore the ways in which the pilot year programming of ACTP evolved over time, due in part to the primary author’s perceived disinterest of the neuroatypical participants. Though initially the neuroatypical participants expressed interest in the project, erratic rehearsal attendance, transportation issues, cognitive fatigue, and stage fright presented challenges for the participants and created obstacles to the theatre process. This led to multiple modifications, including shifting from an ensemble-based mixed-ability devising model to an ethnographic model, and shifting from a full performance to a staged reading and community discussion.

This paper offers an overview of the ACTP and the challenges that led to multiple structural revisions throughout the development of the project. Written from the perspective of the ACTP artistic director, a reflection and analysis on the project’s pilot year concludes with a proposed model for successful community-based theatre work with participants with acquired neurocognitive disabilities and neurotypical volunteers. This paper asks: What are the best practices for creating theatre with/for participants with neurological/neurocognitive deficits? What tensions in objectives, communication, and access arise when a team of neurotypical individuals creates artistic and extracurricular programing for neuroatypical individuals? And how can neurotypical theatre-makers interested in accessibility and inclusion adapt their approach to rise to the challenges presented by these tensions?
Storytelling Beyond the Psychiatric Gaze
Authors: Voronka Jijian
Published: January 2021

This paper explores the politics of resilience and recovery narratives by bringing critical ethnography and auto-ethnographic methods to bear on my own experiences with storytelling distress in different contexts. Inviting people with lived experience to share their stories is now common practice in education, mental health, and broader community venues. Yet even when the intent of the stories shared are to offer systemic critique of mental health epistemes, it is difficult to hear such stories beyond the psychiatric gaze. I argue that individual storytelling practices now get processed through resiliency and recovery metanarratives that continue to position both the problem and its potential solution at the level of individual bodies. By offering an account of my own experiences of storytelling, I explore the limits, risks, and productive functions of this practice. This includes how such narratives, in accumulation, can reify conceptions of the resilient and recovered subject and thus help solidify mental health truth regimes.
Living with Herbert: Mediating Survival and Resilience
Authors: Rajabi Samira
Published: January 2021

In my second year of my doctoral program I was struck by a debilitating bout of vertigo. Not certain of what was happening or why my body suddenly seemed to be in a spinning room that no one else was experiencing, I consulted trusted family and friends in the medical field for an explanation. Most of my friends dismissed my concern as the stress of a new school year or just the circumstances that befall someone who has always been clumsy. I, however, was not swayed in my concern and paying attention to the material realities of my body, I went to the doctor. Over the next several weeks I went from specialist to specialist until an MRI was ordered and a cause was identified. A large benign brain tumor was found, growing off of my hearing and balance nerves and pushing against my brain stem. I was told that though the tumor was benign, it had grown larger than the space available to it, that I was losing my hearing and balance and without treatment I would most certainly die in a few years because of the way the tumor was growing in the space my brainstem required.
“Like Bananas with Brown Spots”
Authors: Nair Aparna
Published: January 2021

Employing an analytical autoethnographic methodology, this paper examines how the polysemic meanings and punctuated character of epilepsy produces social and corporeal vulnerabilities in an Indian childhood. The paper further establishes the importance of the family in influencing individual perceptions and constructions of chronic illness as well as in building resilience or increasing vulnerabilities. In examining the process of research, this paper also makes an argument that disabled researchers in the field can become vulnerable in multivalent ways but also argues that the act of disclosure of epileptic/disabled identities during the research process can become central to building community and resilience. This paper also complicates the often North-centric narrative of disability studies and underlines the importance of social contexts around individual categories of disability or chronic illness.
The ‘Nothing But’
Authors: Aubrecht Katie
Published: January 2021

This paper shares findings from a qualitative study on university student mental health and illness that included digitally recorded interviews with university student services and programs professionals and staff at a Canadian university. Transcripts were thematically coded and analyzed using a disability studies informed interpretive sociological approach. Four key themes emerged: dwelling with disclosure, being open to the ‘nothing but’, understanding oneself as ‘not a counselor’, and coming to terms with the reality that under neoliberalism ‘we all fall’ Two key insights also emerged from the analysis: 1) Access to university-based programs and services is shaped by assumptions about productivity and reputation; 2) Psychiatric knowledge and expertise influences and informs how university student services staff understand and enact their roles within the university system. This paper considers how university-wide productivity-oriented psy-knowledge and practices organize and authorize what one participant described as a ‘hidden curriculum’ of academic success. This hidden curriculum manifests in the form of a referral-based resiliency (govern)mentality in university student service provision. It closes with a reflection on the transformative potential of adopting a “critically maladaptive” (McLaren, 2010, p. 504) approach that is attentive to alterity in university-based student services professional perspectives which appears in the form of a thoughtful “but…”.
Designing Access Together: Surviving the Demand for Resilience
Authors: Ignagni Esther , Chandler Eliza , Collins Kim , Darby Andy , Liddiard Kirsty
Published: January 2021

Together we engaged in a project to co-design and co-create a fictional near-future world that would enable us to interrogate our present techno-social dilemmas.  Accessibility was central to our workshop for the way that access is always central to enacting crip, mad, Deaf, and spoonie[1] communities.  Without access, we cannot meet, discuss, share, struggle, fight, dismantle or create. Crucially, access was tied to our desire to co-create crip near-futures.

 

[1] The term spoonie refers to those who live with chronic conditions. Miserandino, C. (n.d.). Retrieved from: https://butyoudontlooksick.com/articles/written-by-christine/the-spoon-theory/
Disability Barriers in Academia: An Analysis of Disability Accommodation Policies for Faculty at Canadian Universities
Authors: Saltes Natasha
Published: January 2021

This article examines disability accommodation policies for faculty at 42 Canadian universities. Although universities in Canada are legally required to accommodate disabled employees, fewer than half of all universities have a written disability accommodation policy available. The search for disability accommodation policies revealed that there is a lack of consistency in policy implementation as well as language and content. The analysis revealed that disability accommodation policies contain overtly medical language and provisions that work to isolate disabled faculty by reinforcing the notion of competency as able-bodiedness and emphasizing the entanglement between disability, health and medicine. This article encourages universities to acknowledge their role in establishing accessible and inclusive workplaces and concludes with recommendations aimed at addressing some of the gaps and inconsistencies in disability accommodation policies.
... what they wanted were HOMES
Authors: Collins Kimberlee , Zbitnew Anne , Grimard Jennie
Published: January 2021

For those who were incarcerated in institutions like the Orillia Asylum for Idiots, the Ontario Hospital School Orillia and the Huronia Regional Centre, traces of past lives tangle and twist with the present, one story often linked with several.
Digging beneath the Surface: When Disability Meets Gender Identity
Authors: Baril Alexandre , Pullen Sansfaçon Annie , Gelly Morgane A.
Published: January 2021

This article presents the results of a community-based participatory action-research conducted in the province of Quebec with 54 trans youth (15-25 years old). It describes the difficult reality faced by youth who are both trans and disabled and who live at the intersection of cisgenderism (or transphobia) and ableism. The research project, which uses the grounded theory methodology, was conducted in two phases of data collection between 2016 and 2019. In total, 39 of the 54 youth interviewed in person (72.2%) self-identified as disabled. This article therefore focuses on the experience of these young people. We begin this paper with a review of the literature on the theme of “transness and disability.” Then we present the core concepts in our research, including intersectionality, as well as the methodological framework that guided the project, grounded theory. In the following section, we present and discuss the research findings. After showing that, for trans youth, disability has implications at all levels in their lived experience and cannot be separated from their trans identity, we explore the intersections between transness and disability in the lives of trans youth through two main axes. We demonstrate how, on the one hand, impairments and ableism sometimes become obstacles to the realization of gender identity, and how, on the other hand, gender identity and cisgenderism can sometimes become disabling.