bluuebunny/crossref_metadata_2025 huggingface dataset:
Jogo sério: Trilhando saberes escolares
Authors: Abrantes Ana Lucia Rodrigues Cardoso , Lima Bianca Amorim de , Angelo Fernanda de Menezes , Souza Maria de Fátima de , Silva Roberta José da , Pinheiro Shirlei Aparecida , Brito Carlos Alexandre Felício
Published: October 2022

Este artigo apresenta uma proposta de utilização do jogo sério “Trilhando Saberes Escolares”, que teve por finalidade contribuir com uma aula, onde a intenção pedagógica seria introduzir o assunto de um texto a ser trabalhado posteriormente por alunos de uma disciplina do curso de pós-graduação do Mestrado Profissional em Educação, na Região do ABC. Os objetivos dos estudos foram: 1) Conhecer as influências dos organismos internacionais (ex. banco Mundial) na determinação das políticas públicas na educação (ex. a proposta da escola de tempo integral) e 2) Refletir sobre as relações entre políticas públicas, currículo, função da escola e formação docente. É uma pesquisa quantitativa e qualitativa, de natureza descritiva e interpretativa, com características do Design-Based Research (DBR), como proposta por Coob et al (2003). Do ponto de vista quantitativo, as variáveis Satisfação e Interação Social apresentaram, em relação à percepção de aquisição de conhecimento, um índice de correlação de 0,874 e 0,885, respectivamente. Em relação aos dados qualitativos, em uma avaliação global, podemos afirmar que na visão dos participantes a atividade teve um objetivo claro, foi convidativa e os motivou a se engajarem mentalmente na atividade proposta. Conclui-se que esta pesquisa alcançou os objetivos propostos, que foi o de construir e validar um jogo sério como recurso didático para potencializar o processo de ensino e de aprendizagem. Desta forma será possível ampliar as possibilidades de ações pedagógicas em diferentes contextos educacionais.
Índice de sobrepeso e obesidade infantil durante a pandemia em pacientes atendidos em unidades básicas de saúde no oeste do Paraná
Authors: Xavier Eduarda , Pescador Marise Vilas Boas
Published: October 2022

O aumento da incidência da obesidade infantil é uma das pautas mais preocupantes na atualidade, visto que esta é uma condição que favorece o aparecimento de doenças crônicas na fase adulta, como diabetes e hipertensão. No cenário recente da pandemia do novo Coronavírus, o isolamento social em união ao fechamento das escolas contribuiu significativamente para o aumento da prevalência de sobrepeso infantil, pois ocorreu redução na prática rotineira de exercícios físicos e favoreceu o consumo de alimentos hipercalóricos com baixa qualidade nutritiva. O estudo objetivou determinar o índice de sobrepeso e obesidade infantil de pacientes atendidos no período de julho a dezembro de 2020 em três Unidades Básicas de Saúde (UBS) de Cascavel/PR por meio de um método comparativo descritivo, utilizando referências de consultas anteriores e posteriores à pandemia. Foram avaliados dados do índice de massa corporal (IMC) de prontuários médicos referentes a 213 crianças. Do número total de pacientes, 114 (53,5%) apresentaram ganho de peso durante a pandemia. Uma parcela significativa de pacientes apresentava uma dieta desbalanceada e o transtorno de ansiedade foi a comorbidade associada mais relatada pelos familiares nos prontuários. Diversos aspectos da pesquisa estão de acordo com o esperado acerca das consequências da pandemia e o aumento de peso pôde ser comprovado. Concluiu-se que houve um aumento na prevalência de sobrepeso e/ou obesidade como consequência das mudanças impostas pela pandemia, mais estudos devem ser realizados para analisar o grau de comprometimento futuro dessas crianças, com destaque também para a avaliação da saúde mental nesta população.
Possíveis fatores genéticos e fenotípicos que corroboram a gênese do Transtorno do Espectro Autista (TEA): uma revisão integrativa de literatura
Authors: Figueiredo Bárbara Queiroz de , Andrade Ana Clara Alves , Ferreira Hiago Henrique de Souza , Dias Joab Nascimento , Gomes Lucas , Do Valle Keila Cristiane Batista , Carvalho Maria Eduarda Garcia de , Nava Silvia Luana Rodrigues , Gomes Symonne Araújo , Araujo Yohanna Costa
Published: October 2022

O transtorno do espectro autista (TEA) é definido como uma condição comportamental em que a criança apresenta prejuízos ou alterações básicas de comportamento e interação social, dificuldades na comunicação, aquisição verbal e não verbal, alterações cognitivas e presença de comportamentos repetitivos ou estereotipados. Está cada vez mais claro que a genética é a principal responsável pela origem do autismo. Aliado a isso, fatores isolados também podem participar da origem do autismo, e componentes ambientais seriam insultos graves provocados ao cérebro fetal em desenvolvimento durante o período gestacional, bem como fatores gestacionais singulares à progenitora, como a idade avançada dos pais, diabetes mellitus gestacional, pré-eclâmpsia, infecção por rubéola e toxoplasmose. O estudo também aborda fatores protetivos, intrínsecos à mãe, como o uso do ácido fólico, vitamina D, zinco, ômega 3 e amamentação materna.
Implicações do estado nutricional e da imunonutrição na COVID-19: uma revisão literária narrativa
Authors: Silva Crislaine Paula da , Vidigal Fernanda de Carvalho
Published: October 2022

COVID-19 é uma doença causada por vírus da família Coronaviridae, caracterizada por sintomas respiratórios que podem ser leves ou graves, podendo levar a insuficiência respiratória e óbito. O sistema imunológico é a barreira que combate às infecções virais, sendo comprovado na literatura, o impacto da alimentação no desenvolvimento e manutenção de células imunológicas. Perante uma infecção, o gasto energético é aumentado, bem como a necessidade de nutrientes. Desta forma, estado nutricional, alimentação e estilo de vida são considerados relevantes, já que podem afetar a evolução e o bom prognóstico dos pacientes com COVID-19. Objetivou-se avaliar a influência do estado nutricional e da imunonutrição no manejo da infecção pelo SARS-CoV-2. Trata-se de revisão narrativa, na qual foram estudados temas sobre COVID-19, sistema imunológico, infecções virais e nutrientes. Verificou-se que uma alimentação adequada e saudável é fundamental para o funcionamento do sistema imune atuar contra as infecções virais, incluindo a COVID-19. Pesquisas evidenciaram que suplementar alguns micronutrientes aumenta a capacidade de defesa viral, no entanto mais estudos são necessários para comprovar essa hipótese. As alterações no estado nutricional impactam diretamente no curso da doença, agravando o processo inflamatório e aumentando o risco de óbito. Conclui-se que a adequação do estado nutricional, incluindo uma alimentação saudável, com aporte adequado de macronutrientes, vitaminas e minerais, é muito importante para minimizar os efeitos da COVID-19 na saúde.
Práticas pedagógicas no ensino durante a pandemia do COVID-19
Authors: Gomes Geórgia Regina Rodrigues , Faria João Paulo de Oliveira , Nascimento Matheus Carvalho do , Azevedo Filho Edson Terra , Freitas Arnold  de Araujo
Published: October 2022

A pandemia ocasionada pelo Coronavírus impactou significativamente diferentes campos sociais no Brasil, incluindo o sistema educacional e suas legislações. Tal situação obrigou o referido sistema a se reestruturar, organizando o que ficou popularmente conhecido como Ensino Remoto. Tal feito foi essencial para o cumprimento da carga horária mínima exigida por lei para que os estudantes pudessem ser promovidos para os anos subsequentes, bem como para que os docentes construíssem suas práticas pedagógicas permeadas pelas tecnologias digitais de informação e comunicação (TDICs). Visto posto, o presente artigo se fundamentou no sentido de identificar as principais características didáticas e práticas pedagógicas construídas pelos professores da Educação Básica do Município de Itaperuna RJ durante o Ensino Remoto. A metodologia se configurou como exploratória, sendo aplicado um questionário semiestruturado por meio do Google Forms a 54 dcentes atuantes na Educação Básica do referido município. As respostas foram organizadas em gráficos e tabelas buscando quantificar os resultados e, em seguida, promover a discussão da pesquisa. Foi possível identificar que 75% dos docentes optaram por desenvolver aulas mistas, síncronas e assíncronas; as atividades síncronas corresponderam a mais de 80% dos trabalhos desenvolvidos; a principal tecnologia utilizada foi o Google Classroom para apoio aos atendimentos remotos; mais de 90% dos docentes apontaram o uso do Whatsapp como fermenta principal; 72.4% dos professores informaram que as escolas exerceram papel fundamental na elaboração das aulas durante o ensino remoto, entretanto, ainda carecem de maiores ofertas de cursos de aperfeiçoamento e/ou capacitação sobre suporte técnico para o uso das TDICs.
A feasibility study of surface miner
Authors: Ditlef Alexandre , Lima Hernani Mota , Cunha Edmo Rodorvalho , Souza Felipe Ribeiro
Published: October 2022

Due all of the challenges faced for feasible mining, new technologies, software, mining equipment, and ore processing are constantly being developed by equipment manufacturers. The focus of this article is to present the premises necessary for the possible applications within the mining industry of the Continuous Surface Miner – a machine currently being used in coal and phosphate mining operations and being evaluated for its incorporation in other diverse mining projects. This article demonstrates the utilization of this equipment in the field of mineral engineering and how a study should be conducted for its application. Continuous Surface Miner compared to the traditional mine equipment, due to the underestimated productivity of the material to be cut demand a higher availability of equipment fleet. The results of the feasibility study show that the use the continuous surface miner did not present itself to be a better option for the mine equipment.
O uso de celulares na adolescência e sua interferência nas relações interpessoais nesta fase
Authors: Araujo Leila Marcia Guimaraes , Silva Luciana de Araújo Mendes , Moreira Rosana Mendes Maciel
Published: October 2022

A evolução tecnológica acompanhou o desenvolvimento humano e suas necessidades, transformando os hábitos e os comportamentos dos indivíduos diante da sociedade. A invasão da tecnologia na vida das pessoas pode ser mais perceptível quando se trata da adolescência, pois nesta fase o indivíduo está se encontrando consigo mesmo e com o meio onde vive. Nesse contexto, além das transformações físicas, ocorrem também alterações psicológicas e a interferência tecnológica neste período pode acarretar em afastamento dos adolescentes da vida real, mudando seu modo de pensar, agir e se organizar diante do meio. O presente trabalho teve por objetivo, explorar e descrever aspectos relacionados ao uso do celular na adolescência, nas relações interpessoais. A pesquisa foi desenvolvida através de levantamento bibliográfico nos principais recursos que versam sobre o assunto como: artigos e livros. Pode-se concluir que a tecnologia possui consequências negativas e positivas. Ela auxilia os pais, escola e amigos na comunicação, organização de tarefas e localização dos adolescentes, mas ao mesmo tempo seu uso exacerbado pode prejudicar o relacionamento do adolescente com as pessoas e além disso, levar a depressão, problemas psicológicos e ao isolamento social.  Diante dessa realidade é necessária a adoção de medidas que visem minimizar tais impactos.
PENEGAKAN KODE ETIK NOTARIS SEBAGAI UPAYA MENJAGA KEHORMATAN DAN KELUHURAN JABATAN NOTARIS
Authors: Kristiawan Yhan
Published: October 2022

Indonesia sebagai negara hukum menjamin kesederajatan bagi setiap orang di muka hukum yang salah satunya dengan mewujudkan hak bagi setiap orang mendapat kepastian hukum melalui akta Notaris sebagai alat bukti tertulis yang bersifat otentik[1]. Dalam mewujudkan layanan publik, Notaris berkumpul dalam wadah Organisasi Notaris dan dilengkapi dengan Kode Etik Notaris serta alat perlengkapan Perkumpulan (Rapat anggota, Kepengurusan, Dewan Kehormatan, dan Mahkamah Perkumpulan). Kode Etik Notaris berperan dalam mencapai dan menjaga tujuan dari Ikatan Notaris Indonesia (INI) sebagai suatu Perkumpulan yaitu terpeliharanya keluhuran martabat jabatan Notaris. Berdasarkan hal tersebut, terdapat kewajiban bagi Notaris dan orang lain yang menjalankan tugas jabatan Notaris untuk mentaati Kode Etik Notaris yang dibentuk melalui Kongres. Kode Etik Notaris perlu untuk ditegakkan dan Dewan Kehormatan memiliki kewenangan untuk melakukan pembinaan, pengawasan, dan pemberian sanksi dalam rangka penegakan Kode Etik Notaris. Tulisan ini bertujuan untuk menguraikan pengaturan-pengaturan dalam Kode Etik Notaris dalam kaitannya dengan penegakan Kode Etik Notaris dalam perannya mencapai tujuan perkumpulan yaitu terjaganya kehormatan dan keluhuran jabatan Notaris. Penelitian ini didasarkan pada data sekunder yang terdiri dari Kode Etik Notaris, peraturan perundang-undangan, referensi buku, dan informasi dari internet. Hasil penelitian disimpulkan bahwa pengaturan-pengaturan dalam Kode Etik Notaris memiliki peran penting dalam menjaga kehormatan dan keluhuran jabatan Notaris melalui penegakan Kode Etik Notaris.[1] Indonesia, Undang-Undang Tentang Jabatan Notaris,  UU No. 2 Tahun 2014 Tentang Perubahan UU No. 30 Tahun 2004, LN Tahun 2014 Nomor 3, TLN Nomor 5491, Pasal 1 angka 7 menyebutkan “Akta Notaris yang selanjutnya disebut Akta adalah akta autentik yang dibuat oleh atau di hadapan Notaris menurut bentuk dan tata cara yang ditetapkan dalam Undang-Undang ini.”
Én, te, ő
Authors: Nagyházi Bernadette
Published: October 2022

Varga Katalin Én, te, ő című képes meseregénye 1973-ban jelent meg a Móra Kiadónál. Az első megjelenést számos újabb követte, többségében a Móránál (1978, 1982, 1987, 1993, 2013, 2015, 2016, 2018, 2019), illetve a Santosnál 2005-ben és 2006-ban. Ez a többszöri, az utóbbi időben szinten évenkénti megjelenés arra utal, hogy a közel ötvenéves meseregénynek, amely a 8–10 éves tanulók nyelvtantanításának segítését, támogatását, de emellett anyanyelvi kompetenciájuk, logikai gondolkodásuk, metanyelvi kompetenciájuk fejlesztését is szolgálta, ma is van létjogosultsága. A jelen írás bemutatja a meseregény koncepcióját, a meséből a konkrét ismeretekhez átvezető képeket és képsorozatokat. Emellett kritikai elemzésnek veti alá a közvetített nyelvelméleti tartalmat, a kapcsolódó feladatokat, illetve ismerteti egy empirikus kutatáseredményeit arról, hogy az idősebb és fiatalabb generációhoz tartozó pedagógusok felhasználják-e a tanórai felkészülésben, a tanórán, esetleg azon kívül Varga Katalin – önmagában is izgalmas, képsorozatokkal kiegészített – meseregényét.
How Does American Public Opinion React to Overt Anti-Democratic Behavior by Politicians? Quasi-Experimental Evidence from the January 6 Insurrection
Authors: van Noort Sam
Published: October 2022

Do American politicians that clearly violate democratic norms lose significant public support, or does public opinion impose little constraint on anti-democratic politicians? Existing studies have examined this fundamental question using hypothetical survey experiments which, while valuable, suffer from ecological validity and weak treatment concerns. I overcome these problems by studying a novel quasi-experiment created by the fact that Donald Trump's incitement of the January 6 insurrection unexpectedly occurred while Gallup was conducting a nationally representative public opinion survey using random digit dialing. Comparing party identification among respondents that happened to be interviewed just before, and just after, January 6, 2021 suggests that the Republican Party retained 78% of its pre-insurrection support base during the first 1.5 weeks. Even this modest loss was short-lived---in February 2021 the Republican Party already stood at 93% of its pre-insurrection support level. While not zero, the public constraint on anti-democratic behavior is remarkably limited.
Using the PageRank Algorithm to Rank Football Players in a Game
Authors: Iyer Aditya
Published: October 2022

There are many methods to rank football players based on their performance in a game or series of games. However, since most methods are subjective, this paper proposes the PageRank algorithm as an objective method to rank players in a football team, where players can be considered as the nodes, and the passes made between them as the edges of a graph. To achieve this, we consider weighting functions, which are based on parameters which consider the number and quality of passes as well as the actions of individual players in the game. The models generated by these weighting functions are compared with the official rankings of players using the Kendall's Tau Correlation Coefficient in order to find the distance between the two ranking vectors. This paper shows that the PageRank algorithm can be a promising and objective tool for ranking football players in a game.
PENINGKATAN KUALITAS ARTISTIK LINGKUNGAN MELALUI MEDIA MURAL DI RPTRA KELURAHAN KRENDANG, JAKARTA BARAT
Authors: FRANZIA Elda , RESPATI Yosua Reydo , HARYADI Ekananda
Published: October 2022

The Community Service activity held by Trisakti University, Faculty of Art and Design, Visual Communication Design Program, through Multi 2-1 Program Theme â€œThe Enhancement of Knowledge and Environment Quality Trainingâ€œ in Kelurahan Krendang, Kecamatan Tambora, West Jakarta. The Multi Program is prime program from Community Service Agency of Trisakti University, and one of them located at Kelurahan Krendang. The Environmentally Friendly Integrated Public Space (RPTRA) is an open space area functioned as the center of social activity in Kelurahan Krendang including sports and social community activites. RPTRA Krendang in under development and has many blank wall spaces functioned as activity limit area. This program aims in to improve the quality of environment and develop man power creative quality in Kelurahan Krendang. The programâ€™s target is orange troops and the Karang Taruna youngsters at Kelurahan Krendang with trainer from lecturer and students of Visual Communication Design Program. The programâ€™s participants are 16 men with age range 20-40 years old. The method are three activities stages which are (1) training with lecture, discussion, and Q&A method, (2) lecture of mural making procedures, (3) mural making practice with sketching techniques. The results are 7 (seven) wall area painted in mural with variative and creative images made by participants.

Kegiatan Pengabdian kepada Masyarakat ini dilaksanakan oleh Universitas Trisakti, Fakultas Seni Rupa dan Desain, Program Studi Desain Komunikasi Visual melalui program Multi 2-1 dalam tema besar â€œPeningkatan Pengetahuan dan Pelatihan Perbaikan Kondisi Lingkunganâ€ di Kelurahan Krendang, Kecamatan Tambora, Jakarta Barat. Program Multi merupakan program unggulan yang dikelola oleh Lembaga Pengabdian Masyarakat Universitas Trisakti dan salah satunya berlokasi di Kelurahan Krendang. Ruang Publik Terpadu Ramah Lingkungan (RPTRA) merupakan ruang terbuka yang menjadi pusat aktivitas masyarakat di Kelurahan Krendang, termasuk kegiatan olah raga dan kegiatan sosial masyarakat. Kondisi RPTRA Krendang belum terolah dan memiliki banyak area dinding kosong yang juga berfungsi sebagai batas area kegiatan. Kegiatan ini bertujuan untuk perbaikan kualitas lingkungan dan pengembangan kreativitas sumber daya manusia di Kelurahan Krendang. Sasaran kegiatan adalah pasukan oranye dan remaja Karang Taruna di Kelurahan Krendang. Pelatihan diikuti oleh 16 orang peserta dengan rentang usia 20-40 tahun dengan pemateri dosen dan mahasiswa Program Studi Desain Komunikasi Visual. Metode pelatihan dilakukan dalam beberapa tahapan kerja yaitu (1) pelatihan dengan metode ceramah, diskusi, dan tanya jawab, (2) penyuluhan tahapan kerja pembuatan mural, (3) praktik pembuatan mural dengan teknik sketsa langsung. Hasil dari kegiatan ini adalah 7 (tujuh) area dinding yang terolah menjadi mural dengan gambar-gambar yang variatif dan kreatif yang dibuat oleh para peserta pelatihan.
PENINGKATAN EKONOMI KELUARGA MELALUI PENGOLAHAN ASAM TIMOR (TAMARINDUS INDICA) DI DESA BAUMATA UTARA, KECAMATAN TAEBENU, KABUPATEN KUPANG
Authors: Bulkis Bulkis , FINA Yusinta N. , MALLE Noveni M. , FRANS Yudith A. , LONGGO Yanuardi
Published: October 2022

The Timor island is famous with Timor Acid plants which is if it processed properly, it have good economic value. So far the people and the government  is less on giving attention to timor acid so that it is only used as a food spice. This  matter becomes  reason  for doing training in timor acid processing. Partners in this activity are Narwastu Women's Group in Desa Baumata Utara, Kec. Taebenu, kab. Kupang. The Problems  that faced by partners (women's groups)  is related with  the abundance yields  of timor acid and the people donâ€™t know how to process after harvest in order to increase economic value. Write in 1 paragraph. The target and outputs that want to be achieved by the people  especially women's groups  which is able to  process Timor Tamarind Fruit into Juices, tamarind paste and able to  carry out preservation so that it can be save it  for a long time. The method used are  training and demonstration. All activities carried out of four visits on one  the period from June to December 2018 . The activities namely training, mentoring, and monitoring and evaluation. The results of the PkM activities in Desa Baumata Utara, Kec. Taebenu, Kupang Regency is the Narwastu is Women's Group able to  process acids into Tamarind Juice, Tamarind Turmeric Juice, Tamarind Pasta, and can carry out the acid storage process well so that it is durable. The result of PKM activity in Desa BAUMATA Utara, Kec. TAEBENU, Kab. Kupang  is the women's group able to  process Timor Tamarind Fruit into Juices, tamarind paste and able to  carry out preservation so that it can be save it  for a long time.

Pulau Timor terkenal dengan tanaman Asam Timor yang jika diolah dengan baik memiliki nilai ekonomi yang baik. Sejauh ini masyrakat dan pemerintah kurang memperhatikan asam timor sehingga hanya digunakan sebagai bumbu dapur. Hal ini yang menjadi landasan untuk melakukan pelatihan pengolahan asam timor. Mitra dalam kegiatan ini adalah Kelompok Wanita Narwastu Desa Baumata Utara, Kec. Taebenu, Kabupaten Kupang. Permasalahan yang dihadapi mitra (kelompok wanita) berkaitan dengan melimpahnya hasil panen asam timor dan masyrakat belum mengetahui cara pengolahan setelah panen agar dapat meningkatkan nilai ekonomi. Target dan luaran yang ingin yang dicapai adalah masyarakat khususnya kelompok wanita dapat mengolah Buah Asam Timor menjadi Jus, pasta asam dan  bisa melakukan pengawetan sehingga bisa disimpan dalam waktu yang lama. Metode yang digunakan adalah pelatihan dan demonstrasi. Seluruh kegiatan dilaksanakan sebanyak 4

kali kunjungan dalam kurun waktu bulan Juni sampai Desember 2018 yaitu pelatihan, pendampingan, serta monitoring dan evaluasi. Hasil kegiatan PkM di Desa Baumata Utara, Kec. Taebenu, Kabupaten Kupang adalah Kelompok Wanita Narwastu bisa mengolah asam menjadi Jus Asam, Jus Kunyit Asam, Pasta Asam, dan bisa melakukan proses penyimpanan asam dengan baik sehingga tahan lama.
KONSERVASI LINGKUNGAN MELALUI UPAYA KOMPOSTING TANDAN KOSONG KELAPA SAWIT (TKKS) DI DESA CIKARAWANG, KECAMATAN DRAMAGA, KABUPATEN BOGOR
Authors: SUSILO SUSILO , SUSANTO Tejo , Nurhidayat Nurhidayat
Published: October 2022

Palm oli waste empty bunches (tkks) corn cob, corn leaf, rice straw, soybean leaf and others are very abundant in Cikarawang village, Dramaga district, Bogor Regency as an area of agricultural centers, especially during the harvest season. Along with the high production of palm oil, the solid waste TKKS often raises its own problems. Processing is not optimal, such as long-time composting often results in a very large pile of TKKS and potentially a host of pests and diseases. Whereas solid waste in the form of empty bunches of palm oil can be processed efficiently and effectively to be used as compost. Community service activities through Iptek Program for Society (IbM) in Cikarawang Village, Dramaga district, Bogor Regency directed to empower the community to utilize agricultural waste for environmental conservation. The method used is training and demonstration of how to practice the posting. Program participants are members of Cikarawang Village Farmer Group (Gapoktan). The results of empowerment through training and practice are positively responded by the participants. The farmer empowerment Program in this environmental conservation in the long term is expected to be a demonstration for farmer groups in other areas with better capacity and quality.

Limbah tandan kosong kelapa sawit (TKKS/janjang kosong) tongkol jagung, daun jagung, jerami padi, daun kedelai dan lain-lain sangat melimpah di desa Cikarawang Kecamatan dramaga Kabupaten Bogor sebagai suatu daerah sentra pertanian, terutama pada saat musim panen. Seiring dengan tingginya produksi minyak sawit, limbah padat TKKS sering menimbulkan permasalahan tersendiri. Pengolahan yang belum optimal, seperti pengomposan yang memakan waktu lama sering mengakibatkan tumpukan TKKS yang sangat besar dan berpotensi menjadi inang hama dan penyakit. Padahal limbah padat berupa tandan kosong kelapa sawit dapat diolah secara efisien dan efektif untuk dijadikan kompos. Kegiatan pengabdian kepada masyarakat melalui program Iptek bagi Masyarakat (IbM) di Desa Cikarawang, Kecamatan Dramaga, Kabupaten Bogor diarahkan untuk pemberdayaan masyarakat memanfaatkan limbah pertanian untuk konservasi lingkungan. Metode yang digunakan adalah pelatihan dan demonstrasi cara praktik pengomposan. Peserta program adalah anggota kelompok tani Desa Cikarawang (Gapoktan). Hasil pemberdayaan melalui pelatihan dan praktik direspons positif oleh peserta. Program pemberdayaan petani dalam konservasi lingkungan ini dalam jangka panjang diharapkan mampu menjadi percontohan bagi kelompok tani di daerah lain dengan kapasitas dan kualitas yang lebih baik.
PENGEMBANGAN MEDIA PEMBELAJARAN BERBASIS DO IT YOURSELF HOME PROJECT BAGI GURU TK ISLAMIC KIDS CORNER BOGOR
Authors: Kosasih Fauzy , Juhana Juhana , Ardiasih Lidwina Sri , Riyanti Rahayu Dwi , Suratinah Suratinah
Published: October 2022

This community service program aims to train Bogor Islamic Kids Corner (IKC) Kindergarten teachers to develop DIY home project-based learning media for students. This activity involves partners consisting of teachers and students in partner schools. This activity begins with an initial visit to analyze the situation and needs of the local community. From the results of the visit, it was identified and agreed that community service activities (Abdimas) were focused on developing learning media based on the DIY home project considering that teaching and learning activities were still carried out from home (emergency learning). From the results of the implementation of Abdimas activities, it can be reported that from four training sessions with IKC Kindergarten teachers, the teachers have been able to develop and utilize DIY home project-based learning media with students. Both teachers and students were enthusiastic and active in participating in every series of community service activities while still adhering to health protocols.
 
Program pengabdian kepada masyarakat dengan judul IbM Pengembangan Media Pembelajaran Berbasis DIY Home Project bagi Guru TK IKC Bogor ini bertujuan melatih guru TK Islamic Kids Corner (IKC) Bogor untuk mengembangkan media pembelajaran berbasis DIY home project bagi siswa. Kegiatan ini melibatkan mitra yang terdiri dari para guru dan siswa di sekolah mitra. Kegiatan ini dimulai dengan kunjungan awal untuk menganalisis situasi dan kebutuhan masyarakat di lokasi. Dari hasil kunjungan berhasil diidentifikasi dan disepakati bahwa kegiatan pengabdian kepada masyarakat (PkM) difokuskan pada pengembangan media belajar berbasis DIY home project mengingat kegiatan belajar mengajar masih dilakukan dari rumah (pembelajaran jarak jauh). Dari hasil pelaksanaan kegiatan PkM, dapat dilaporkan bahwa dari empat kali pelatihan dengan para guru TK IKC maka para guru telah mampu mengembangkan dan memanfaatkan media pembelajaran berbasis DIY home project bersama para siswa. Baik para guru maupun para siswa antusias dan aktif dalam mengikuti setiap rangkaian kegiatan PkM dengan tetap menaati protokol kesehatan.
PENYULUHAN DOOR TO DOOR TENTANG COVID-19 DAN ISOLASI MANDIRI DI DESA SUKAMELANG KECAMATAN KROYA KABUPATEN INDRAMAYU
Authors: Widyastuti Setyo Dwi , Setiawan Aldi Pristy Ghamely , Khotimah Siti Khusnul , Mitamumtazah Maila
Published: October 2022

Covid-19 cases have increased in almost all areas in West Java, one of which is in Indramayu Regency. A total of 9,795 were confirmed positive for Covid-19, 1,179 people are still being treated, 8,353 have recovered and 263 people have died. Kroya District as one of the sub-districts in Indramayu Regency as of July 10, 2021, there were 116 confirmed cases of Covid-19 and in Sukamelang Village as of July 12, 2021, based on secondary data obtained from the Kroya Health Center, the prevalence of Covid-19 cases was 29 people. Confirmed positive, 14 people are doing isoman, 15 people have completed isolation / recovered. The purpose of this service activity is to increase public knowledge about Covid-19 and self-isolation in accordance with government recommendations. Counseling activities are carried out door to door with the target of all RT heads in Sukamelang Village. Counseling is done by the lecture method. The media used were leaflets, mobile phones, pre-test and post-test sheets. The counseling activity succeeded in increasing the knowledge of the RT Chair about Covid-19 and self-isolation. This can be seen from the increase in the value of knowledge from before and after the counseling was carried out, which was 11.2. 

 

Kasus Covid-19 meningkat hampir di semua wilayah yang ada di Jawa Barat, salah satunya adalah di Kabupaten Indramayu. Sebanyak 9.795 terkonfirmasi positif Covid-19, 1.179 orang masih perawatan, 8.353 sembuh dan 263 orang meninggal dunia. Kecamatan Kroya sebagai salah satu kecamatan di Kabupaten Indramayu per tanggal 10 Juli 2021 kasus Covid-19 terdata 116 orang yang terkonfirmasi positif dan di Desa Sukamelang per tanggal 12 Juli 2021 berdasarkan data sekunder yang diperoleh dari Puskesmas Kroya prevalensi kasus Covid-19 sebanyak 29 orang yang terkonfirmasi positif, 14 orang sedang melakukan isoman, 15 orang selesai isolasi/sembuh. Tujuan dari kegiatan pengabdian ini meningkatkan pengetahuan masyarakat tentang Covid-19 dan isolasi mandiri sesuai dengan anjuran pemerintah. Kegiatan penyuluhan dilakukan secara door to door dengan sasaran seluruh Ketua RT di Desa Sukamelang. Penyuluhan dilakukan dengan metode ceramah. Media yang digunakan adalah leaflet, handphone, lembar pre-test dan post-test. Kegiatan penyuluhan berhasil meningkatkan pengetahuan Ketua RT tentang Covid-19 dan isolasi mandiri. Hal ini dapat dilihat dari peningkatan nilai pengetahuan dari sebelum dan sesudah penyuluhan dilakukan, yaitu sebesar 11,2.
Positive Impact of The Covid-19 Pandemic on The World of Education
Authors: Almaududi Ausat Abu Muna
Published: October 2022

The Covid-19 pandemic, which has disrupted the order of life in the world of education, is still ongoing; various efforts are being made to end the pandemic period as soon as possible. Even in the midst of a pandemic, the world of education must be given special attention in order to avoid being negatively impacted. The opportunity to advance the world of education through online learning is a solution to meet educational standards through the use of information technology so that students and teachers are interconnected and the teaching and learning process can still be carried out properly through the use of technology. The method used in this study is qualitative, with approach content analysis and descriptive presentation. As a source of research data, the author examines documents in the form of text, news, journals, and newspapers. Although the pandemic had many negative consequences, it had a positive impact on the world of education. This positive impact can inspire the community to persevere in the face of adversity in order to achieve more advanced educational goals. Among the many positive effects of online learning during the Covid-19 pandemic, one has the greatest impact on the world of education: it accelerates educational transformation.
Innovative immune mechanisms and antioxidative therapies of intervertebral disc degeneration
Authors: Wei Bingqian , Zhao Yingjing , Li Weihang , Zhang Shilei , Yan Ming , Hu Zebing , Gao Bo
Published: October 2022

Intervertebral disc degeneration (IDD) is the basic pathological process of many degenerative diseases of the spine, characterized by series of symptoms, among which low back pain (LBP) is the most common symptom that patients suffer a lot, which not only makes patients and individual families bear a huge pain and psychological burden, but also consumes a lot of medical resources. IDD is usually thought to be relevant with various factors such as genetic predisposition, trauma and aging, and IDD progression is tightly relevant with structural and functional alterations. IDD processes are caused by series of pathological processes, including oxidative stress, matrix decomposition, inflammatory reaction, apoptosis, abnormal proliferation, cell senescence, autophagy as well as sepsis process, among which the oxidative stress and inflammatory response are considered as key link in IDD. The production and clearance of ROS are tightly connected with oxidative stress, which would further simulate various signaling pathways. The phenotype of disc cells could change from matrix anabolism-to matrix catabolism- and proinflammatory-phenotype during IDD. Recent decades, with the relevant reports about oxidative stress and inflammatory response in IDD increasing gradually, the mechanisms researches have attracted much more attention. Consequently, this study focused on the indispensable roles of the oxidative stress and inflammatory response (especially macrophages and cytokines) to illustrate the origin, development, and deterioration of IDD, aiming to provide novel insights in the molecular mechanisms as well as significant clinical values for IDD.
Biomechanical effects of medial meniscus radial tears on the knee joint during gait: A concurrent finite element musculoskeletal framework investigation
Authors: Wang Sentong , Hase Kazunori , Kita Shunsuke , Ogaya Shinya
Published: October 2022

The biomechanical variation in the knee during walking that accompanies medial meniscal radial tears stemming from knee osteoarthritis (OA) has not been explored. This study introduced a finite element musculoskeletal model using concurrent lower limb musculoskeletal dynamics and knee joint finite element analysis in a single framework and expanded the models to include knees with medial meniscal radial tears and total medial meniscectomy. The radial tears involved three locations: anterior horn, midbody, and posterior horn with grades of 33%, 50%, and 83% of the meniscus width. The shear and hoop stresses of the tear meniscus and tibial cartilage contact load, accompanying tears, and postmeniscectomy were evaluated during the stance phase of the gait cycle using the models. In the 83% width midbody tear group, shear stress at the end of the tear was significantly greater than in the intact meniscus and other tear groups, and the maximum shear stress was increased by 310% compared to the intact meniscus. A medial meniscus radial tear has a much smaller effect on the tibial cartilage load (even though in the 83% width tear, the cartilage/total load ratio increased by only 9%). However, the contact force on the tibial cartilage with total postmeniscectomy was increased by 178.93% compared with a healthy intact meniscus, and the peak contact pressure after meniscectomy increased from 11.94 to 12.45 MPa to 17.64 and 13.76 MPa, at the maximum weight acceptance and push-off, respectively. Our study shows that radial tears with larger medial meniscus widths are prone to high stress concentrations at the end of the tears, leading to the potential risk of complete meniscal rupture. Furthermore, although the tears did not change the cartilage load distribution, they disrupted the circumferential stress-transmitting function of the meniscus, thus greatly increasing the likelihood of the onset of knee OA. The significant increase in the tibial cartilage load with total postmeniscectomy indicates a potential risk of OA flare-ups. This study contributes to a better understanding of meniscal tear-induced OA biomechanical changes during human activities and offers some potential directions for surgical guidance of meniscectomies and the prophylaxis and treatment of OA.
Mammalian middle ear mechanics: A review
Authors: Ugarteburu Maialen , Withnell Robert H. , Cardoso Luis , Carriero Alessandra , Richter Claus-Peter
Published: October 2022

The middle ear is part of the ear in all terrestrial vertebrates. It provides an interface between two media, air and fluid. How does it work? In mammals, the middle ear is traditionally described as increasing gain due to Helmholtz’s hydraulic analogy and the lever action of the malleus-incus complex: in effect, an impedance transformer. The conical shape of the eardrum and a frequency-dependent synovial joint function for the ossicles suggest a greater complexity of function than the traditional view. Here we review acoustico-mechanical measurements of middle ear function and the development of middle ear models based on these measurements. We observe that an impedance-matching mechanism (reducing reflection) rather than an impedance transformer (providing gain) best explains experimental findings. We conclude by considering some outstanding questions about middle ear function, recognizing that we are still learning how the middle ear works.
Lung epithelium development and airway regeneration
Authors: Eenjes Evelien , Tibboel Dick , Wijnen Rene M.H. , Rottier Robbert J.
Published: October 2022

The lung is composed of a highly branched airway structure, which humidifies and warms the inhaled air before entering the alveolar compartment. In the alveoli, a thin layer of epithelium is in close proximity with the capillary endothelium, allowing for an efficient exchange of oxygen and carbon dioxide. During development proliferation and differentiation of progenitor cells generates the lung architecture, and in the adult lung a proper function of progenitor cells is needed to regenerate after injury. Malfunctioning of progenitors during development results in various congenital lung disorders, such as Congenital Diaphragmatic Hernia (CDH) and Congenital Pulmonary Adenomatoid Malformation (CPAM). In addition, many premature neonates experience continuous insults on the lung caused by artificial ventilation and supplemental oxygen, which requires a highly controlled mechanism of airway repair. Malfunctioning of airway progenitors during regeneration can result in reduction of respiratory function or (chronic) airway diseases. Pathways that are active during development are frequently re-activated upon damage. Understanding the basic mechanisms of lung development and the behavior of progenitor cell in the ontogeny and regeneration of the lung may help to better understand the underlying cause of lung diseases, especially those occurring in prenatal development or in the immediate postnatal period of life. This review provides an overview of lung development and the cell types involved in repair of lung damage with a focus on the airway.
Nuclear size rectification: A potential new therapeutic approach to reduce metastasis in cancer
Authors: Schirmer Eric C. , Latonen Leena , Tollis Sylvain
Published: October 2022

Research on metastasis has recently regained considerable interest with the hope that single cell technologies might reveal the most critical changes that support tumor spread. However, it is possible that part of the answer has been visible through the microscope for close to 200 years. Changes in nuclear size characteristically occur in many cancer types when the cells metastasize. This was initially discarded as contributing to the metastatic spread because, depending on tumor types, both increases and decreases in nuclear size could correlate with increased metastasis. However, recent work on nuclear mechanics and the connectivity between chromatin, the nucleoskeleton, and the cytoskeleton indicate that changes in this connectivity can have profound impacts on cell mobility and invasiveness. Critically, a recent study found that reversing tumor type-dependent nuclear size changes correlated with reduced cell migration and invasion. Accordingly, it seems appropriate to now revisit possible contributory roles of nuclear size changes to metastasis.
Autophagy controls Wolbachia infection upon bacterial damage and in aging Drosophila
Authors: Hargitai Dávid , Kenéz Lili , Al-Lami Muna , Szenczi Győző , Lőrincz Péter , Juhász Gábor
Published: October 2022

Autophagy is a conserved catabolic process in eukaryotic cells that degrades intracellular components in lysosomes, often in an organelle-specific selective manner (mitophagy, ERphagy, etc). Cells also use autophagy as a defense mechanism, eliminating intracellular pathogens via selective degradation known as xenophagy. Wolbachia pipientis is a Gram-negative intracellular bacterium, which is one of the most common parasites on Earth affecting approximately half of terrestrial arthropods. Interestingly, infection grants the host resistance against other pathogens and modulates lifespan, so this bacterium resembles an endosymbiont. Here we demonstrate that Drosophila somatic cells normally degrade a subset of these bacterial cells, and autophagy is required for selective elimination of Wolbachia upon antibiotic damage. In line with these, Wolbachia overpopulates in autophagy-compromised animals during aging while its presence fails to affect host lifespan unlike in case of control flies. The autophagic degradation of Wolbachia thus represents a novel antibacterial mechanism that controls the propagation of this unique bacterium, behaving both as parasite and endosymbiont at the same time.
Melatonin signalling in Schwann cells during neuroregeneration
Authors: Klymenko Andrii , Lutz David
Published: October 2022

It has widely been thought that in the process of nerve regeneration Schwann cells populate the injury site with myelinating, non–myelinating, phagocytic, repair, and mesenchyme–like phenotypes. It is now clear that the Schwann cells modify their shape and basal lamina as to accommodate re–growing axons, at the same time clear myelin debris generated upon injury, and regulate expression of extracellular matrix proteins at and around the lesion site. Such a remarkable plasticity may follow an intrinsic functional rhythm or a systemic circadian clock matching the demands of accurate timing and precision of signalling cascades in the regenerating nervous system. Schwann cells react to changes in the external circadian clock clues and to the Zeitgeber hormone melatonin by altering their plasticity. This raises the question of whether melatonin regulates Schwann cell activity during neurorepair and if circadian control and rhythmicity of Schwann cell functions are vital aspects of neuroregeneration. Here, we have focused on different schools of thought and emerging concepts of melatonin–mediated signalling in Schwann cells underlying peripheral nerve regeneration and discuss circadian rhythmicity as a possible component of neurorepair.
Recent progresses and challenges in aqueous lithium–air batteries relating to the solid electrolyte separator: A mini-review
Authors: Chen Peng , Bai Fan , Deng Jun wen , Liu Bin , Zhang Tao
Published: October 2022

The lithium–air (Li–air) battery utilizes infinite oxygen in the air to store or release energy through a semi-open cathode structure and bears an ultra-high theoretical energy density of more than 1,000 Wh/kg. Therefore, it has been denoted as the candidate for next-generation energy storage in versatile fields such as electric vehicles, telecommunications, and special power supply. Among all types of Li–air batteries, an aqueous Li–air battery bears the advantages of a high theoretical energy density of more than 1,700 Wh/kg and does not have the critical pure oxygen atmosphere issues in a non-aqueous lithium–air battery system, which is more promising for the actual application. To date, great achievements have been made in materials’ design and cell configurations, but critical challenges still remain in the field of the solid electrolyte separator, its related lithium stripping/plating at the lithium anode, and catholyte design. In this mini-review, we summarized recent progress related to the solid electrolyte in aqueous Li–air batteries focusing on both material and battery device development. Moreover, we proposed a discussion and unique outlook on improving solid electrolyte compatibility and battery performance, thus designing an aqueous Li–air battery with higher energy density and better cycle performance in the future.
FOXO1 inhibits FSL-1 regulation of integrin β6 by blocking STAT3 binding to the integrin β6 gene promoter
Authors: Xu Mingyan , Huang Jie , Zhu Feixiang , Shen Kailun , Liu Fan , Deng Xiaoling
Published: October 2022

Integrin β6 (ITGB6), an epithelial-specific receptor, is downregulated in the gingival epithelium of periodontitis and is associated with inflammation response and periodontitis development. However, the transcriptional regulatory mechanism of ITGB6 downregulation in the human gingival epithelium remains unclear. Fibroblast-stimulating lipopeptide-1 (FSL-1), an oral biofilm component, promotes an epithelial cell-driven proinflammatory response in periodontitis partially by suppressing ITGB6 expression. The aim of the current study was to investigate the transcriptional regulatory mechanism of ITGB6 inhibition by FSL-1 in human epithelial cells (HaCaT and primary human gingival epithelial cells), and to delineate the transcriptional mechanism of ITGB6 suppression in periodontitis. We found that FSL-1 inhibited ITGB6 transcription through increasing forkhead box protein O1 (FOXO1) expression and inhibiting signal transducer and activator of transcription 3 (STAT3) activation. Furthermore, FOXO1 bound to STAT3 directly, leading to decreased STAT3 phosphorylation induced by FSL-1. Consequently, the binding of phosphorylated STAT3 to the ITGB6 promoter was decreased, and ITGB6 transcription was therefore downregulated following FSL-1 stimulation. The reciprocal action of STAT3 and FOXO1 on ITGB6 downregulation was also confirmed by the immunostaining of the inflammatory epithelium associated with periodontitis. Our findings suggest that the interaction of FOXO1–STAT3 may be a useful signal target for the treatment of periodontitis.
The determinants of investment fraud: A machine learning and artificial intelligence approach
Authors: Lokanan Mark
Published: October 2022

Investment fraud continues to be a severe problem in the Canadian securities industry. This paper aims to employ machine learning algorithms and artificial neural networks (ANN) to predict investment in Canada. Data for this study comes from cases heard by the Investment Industry Regulatory Organization of Canada (IIROC) between June 2008 and December 2019. In total, 406 cases were collected and coded for further analysis. After data cleaning and pre-processing, a total of 385 cases were coded for further analysis. The machine learning algorithms and artificial neural networks were able to predict investment fraud with very good results. In terms of standardized coefficient, the top five features in predicting fraud are offender experience, retired investors, the amount of money lost, the amount of money invested, and the investors' net worth. Machine learning and artificial intelligence have a pivotal role in regulation because they can identify the risks associated with fraud by learning from the data they ingest to survey past practices and come up with the best possible responses to predict fraud. If used correctly, machine learning in the form of regulatory technology can equip regulators with the tools to take corrective actions and make compliance more efficient to safeguard the markets and protect investors from unethical investment advisors.