bluuebunny/crossref_metadata_2025 huggingface dataset:
Genetic variants of interferon lambda-related genes and chronic kidney disease susceptibility in the Korean population
Authors: Kwak Jin Ho , Paek Jin Hyuk , Yu Gyeong Im , Han Seungyeup , Park Woo Yeong , Kim Yaerim , Shin Dong Hoon , Jin Kyubok
Published: February 2022

Background: Chronic kidney disease (CKD) is a common condition leading to renal dysfunction and is closely related to increased cardiovascular and mortality risk. CKD is an important public health issue, and recent genetic studies have verified common CKD susceptibility variants. This research examines the interrelationship between candidate genes polymorphisms of interferon lambda (IFNL) induction, its signaling pathway, and CKD. Methods: Seventy-five patients with advanced CKD and 312 healthy subjects (as controls) participated in this research. A replication set composed of 172 patients with advanced CKD and 365 controls was used for additional analysis. The genotype of single nucleotide polymorphisms (SNPs) was determined by the Axiom Genome-Wide Human Assay and SNaPshot assay. Results: The SNP of IFNL3 was significantly associated with CKD in the codominant (p = 0.02) and dominant models (p = 0.02). In addition, the SNPs of IFNL2 were significantly associated with CKD in the dominant model (p = 0.03), and the SNP of interferon alpha receptor 2 (IFNAR2) was significantly associated with CKD in the log-additive model (p = 0.03). Concerning rs148543092, in the IFNL3 gene, a significant association was observed after pooling the original and replication sets. Conclusion: These results indicate that SNPs in the IFNL induction and signal pathway may be associated with CKD risk in the Korean population. Finally, our results also show that the IFNL3 gene variant may be associated with CKD risk.
PENERAPAN PENDEKATAN KONTEKSTUAL DALAM PEMBELAJARAN IPA DI SEKOLAH DASAR
Authors: Arlis Syamsu
Published: February 2022

The contextual science learning strategy can be carried out to the optimum if supported by teachers” creativity and capability to make use of the students, their school, and its environment. The problem is whether teachers of students, learning science already have the capability to develop and implement a contextual learning strategy in their student. This paper is written for the purpose of increasing those teachers” knowledge and understanding of the aforesaid learning strategy in ordr that they can develop and to implement bit in their science classes. Being contextual, it is a strategy relating instructional content with real situations of the leaners and encouraging them to relate academic knowledge to its application in their lives as individuals and family or community members. Contextual learning has the following characteristics: 1) emphasizing problem solving, 2) recognizing that teaching and learning need to occur in multiple context, 3) assisting students in learning hoe to monitor their learning so that they become self-regulated learners, 4) anchoring teach ing in the diverse life context of students, 5) encouraging students to learn from from each other, and.  6) employing authentic assessment.
PENATAAN TAMAN BACAAN MASYARAKAT (TBM) SEBAGAI SARANA PEMBELAJARAN WARGA BELAJAR PENDIDIKAN NONFORMAL
Authors: Irmawita Irmawita
Published: February 2022

Penelitian ini dilatar belakangi oleh berbagai program pendidikan nonformal yang dilaksanakan di masyarakat seperti; program pendidikan keaksaraan fungsional, pendidikan kesetaraan, pendidikan kecakapan hidup dan pendidikan kepemudaan. Program pendidikan nonformal ini dilaksanakan oleh PKBM, SKB maupun LSM yang merupakan lembaga pendidikan nonformal. Mendukung pelaksanaan pendidikan nonformal ini disediakan Taman Bacaan Masyarakat(TBM). Taman Bacaan Masyarakat (TBM) merupakan perpustakaan masyarakat yang menyediakan koleksi bahan bacaan , dapat dimanfaatkan oleh warga belajar untuk meningkatkan pengetahuannya, tempat berdiskusi dan bertukar pikiran sesama warga belajar setelah membaca sumber bacaan. Bahan bacaan yang ada di TBM cendrung menyediakan koleksi bacaan yang sesuai dengan kebutuhan belajar masyarakat seperti buku tentang pertanian, agama, penataan hidup rumah tangga dan sebagainya yang dapat menambah pengalaman tentang pekerjaan dan menata kehidupan dari warga belajar. Penelitian ini dilakukan di kota Padang , yang menjelaskan penataan TBM sebagai sarana pembelajaran warga belajar pendidikan nonformal, meliputi aspek pemilihan lokasi, pelaksanaan sosialisasi, ketersediaan sarana dan prasarana, penetapan waktu, pelaksanaan pengelolaan dan keadaan  koleksi bahan bacaan. Jenis penelitian ini adalah  deskriptif kuantitatif, dengan subjek penelitian warga belajar yang memanfaatkan sarana Taman Bacaan Masyarakat. Hasil penelitiannya adalah sebagian besar dari warga belajar menyatakan dari aspek pemilihan lokasi, pelaksanaan sosialisasi, ketersediaan sarana dan prasarana, penempatan waktu, pelaksanaan pengelolaan dan keadaan koleksi bacaan sudah tertata dengan baik, dan taman bacaan masyarakat sudah difanfaatkan oleh warga belajar pendidikan nonformal sebagai pusat pembelajaran.
Family Business Succession in the V3 Countries
Authors: Luštický Martin , Musil Martin
Published: February 2022

This paper reacts on one of the main issues the family businesses are facing with – handling the business succession process. The aim of the paper is to analyze the process of family business handover and its support from a side of the regional authorities in the South Bohemia Region (Czech Republic), the Presov Region (Slovakia) and the Mazowiecke Region (Poland). The research framework combines face-to-face interviews and impersonal questionnaire survey to obtain data. It applies standard management data analyzing methods to identify the key strategic objectives and tasks for facilitating and sustaining the family businesses and the business succession process. The objectives and tasks are structured in the following areas: (I) Information Gathering & Monitoring, (II) Planning & Implementation, (III) Support & Facilitation, (IV) Cooperation & Coordination. In addition, the tasks are enriched of various good practices from analyzed regions to enhance their impact in practice.
Reflections on Decolonization and X_aaydaG_a Tll Yahda TllG_uhlG_a: a Haida Justice System
Authors: McGuire Michaela Mary
Published: February 2022

In this article I present an overview of findings from research into the formation of a sovereign Haida Tll Yahda justice system. I briefly examine the imposition of colonial governance, justice, and ways of being on suppressing Haida ways of life. Through a series of semi-structured interviews I addressed the following research questions: What does justice mean to the Haida? How could Haida conceptions of justice be implemented in modern day? In this paper, I focus on two themes; namely, Building capacity for Tll Yahda and Establishing Tll Yahda. The results of this research illuminate the importance of continued decolonization – and that re-instituting our own sovereign ways of doing justice through a Haida Tll Yahda system is possible, while also offering important considerations for decolonization and ensuring Canada is held accountable.
Remakes, actualizaciones y homenajes fílmicos en la obra cinematográfica de John Carpenter
Authors: Rodríguez de Austria Giménez de Aragón Alfonso M. , Iturbe Tolosa Andoni
Published: February 2022

La obra audiovisual del director John Carpenter (Nueva York, 1948) está estrechamente relacionada con el concepto de remake. Perteneciente a la generación de directores promotora del “nuevo Hollywood”, que renovó el cine estadounidense en los años 70 desde el punto de vista estético y empresarial (muchos de ellos eran a la vez directores y productores, algo poco común en el Hollywood clásico), Carpenter se sirvió del cine clásico como fuente de inspiración, especialmente de la obra de su admirado Howard Hawks, al quien homenajea en varias ocasiones. Además de reelaborar obras clásicas, la propia obra de Carpenter ha sido fruto de reelaboraciones posteriores, estando él mismo en el equipo productor de algunos de los remakes de sus películas. El objetivo de presente artículo es analizar la obra de John Carpenter más relacionada con el concepto de remake, y situarla en el complejo universo de relaciones  intertextuales creado por el autor y engrandecido por autores posteriores.
Tehergépkocsi szokásjellemzők feltárása pozícióadatok alapján
Authors: Albert Gábor , Miksztai Péter
Published: February 2022

Az Európai Unió nagy hangsúlyt fektet arra, hogy a tehergépkocsi-vezetők részére kötelező pihenőidők eltöltésére megfelelő és tervezhető feltételeket biztosítson. Ennek érdekében az egyes országok illetékes szervei erőfeszítéseket tesznek, aminek sikeressége mérhető interjúkkal, de megismerhető a pihenők használatának feltárásán keresztül is.
Városi járműforgalom térbeli becslése kernel módszerek segítségével
Authors: Varga Balázs , Tettamanti Tamás
Published: February 2022

A modern, intelligens forgalomirányító rendszerek számára a közlekedési hálózat minél pontosabb valós idejű ismerete szükséges. A bemutatott módszer segítségével a detektorok nélküli útszakaszok forgalomnagysága is megbecsülhető.
A Study on Prevalence and Severity of Internet Addiction Among Students of a Degree College of Etawah City Uttar Pradesh
Authors:   Junior Resident, Department of Community Medicine, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India, Kumar Vineet
Published: February 2022

Background: The rapid expansion and proliferation of the internet has provided better opportunities for communication, information and social interaction. However, the excessive undisciplined use by some individuals has led to the emergence of the concept of internet addiction. This study aims to determine the prevalence and pattern of Internet addiction among degree college students by using Internet Addiction Test in Etawah City. Methods: A cross-sectional study was conducted among 235-degree college students during year 2019. Data was collected by using structured proforma including socio-demographic variables and Young’s 20-item Internet Addiction Test (IAT) questionnaire. Data was coded on Microsoft excel and Statistical analysis done by SPSS version 25. Results: Prevalence of internet addiction by using Young’s original criteria was 4.68%. Internet addiction was significantly more common in males than females (p<0.05). This study reveals that according to IAT score, 40.43% were average users, 54.89% were possible addicts and 4.68% were addicts. Chi square test was applied to determine association, gender and internet addiction which, was found to be statistically significant (p = 0.03). Conclusion: Prevalence of internet addiction was 4.68% with male predominance indicating that internet addiction is a growing problem. Prevalence of possible addict was also alarming which was 54.89%. Early recognition of internet addiction and appropriate preventive measures should be taken and awareness campaign should be regularly conducted regarding use of internet and its addiction among the students.
Most veterinarians treating exotic animals use formularies to select drug dosages without consistently checking their sources
Authors: Girolamo Nicola Di , Caron Marianne , Brandão João , Reynders Reint Meursinge
Published: February 2022

OBJECTIVE

To assess what information sources veterinarians use to select drug dosages for treating exotic animals and how they implement this information.

SAMPLE

936 veterinarians from Europe, Asia, Australia, Africa, and the Americas.

PROCEDURES

An anonymous, online survey was used to collect data on information sources used for dosage decisions by veterinarians treating exotic species. Logistic regression models were built to identify associations between individual characteristics and primary outcomes.

RESULTS

Respondents reported their single most common source for establishing drug dosages as formularies (682/936 [72.9%]), followed by scientific journals (96 [10.3%]), other textbooks (68 [7.3%]), colleagues (47 [5.0%]), or continuing education notes (38 [4.1%]). Over two-thirds of the respondents (645, 68.9%) consulted a specific exotic animal formulary for establishing drug dosages in most situations. Of the 936 respondents, 407 (43.5%) reported that they sometimes (318 [34.0%]) or never (89 [9.5%]) checked the source of a dosage in a textbook or a formulary, 503 (55.3%) reported that they sometimes (399 [42.6%]) or never (104 [11.1%]) searched the original publication on a dosage, and 486 (51.9%) reported that they would base their dosage decision on the abstract of an article if they had no access to the full-text. Several respondents’ reported characteristics were significant predictors of primary outcomes.

CLINICAL RELEVANCE

Considering our findings, we recommend authors of formularies and textbooks should focus on evidence-based information and state clearly when information is anecdotal. Tailored strategies to educate veterinarians treating exotic animals on the importance of primary sources are also recommended.
Transformation of Residential Space as an Adaptation Process during the COVID-19 Pandemic
Authors: Anisa Anisa , Lissimia Finta , Nur'aini Ratna Dewi , Ashadi Ashadi , Mokhtar Munirah Radin Mohd
Published: February 2022

A residence is a place to live that accommodates daily activities. Under normal conditions, housing is used as a place to unwind after work and school outside the home. Since December 2019 major changes have taken place globally that have an impact on housing. This change was due to the rapid spread of the COVID-19 virus and reached various regions. Changes due to the spread of the Covid-19 virus have caused changes in the order of life because all activities that were initially carried out outside the home, have shifted to being carried out indoors. This happens because to reduce the impact of the spread of the virus, humans must practice social distancing. The biggest change that occurred was the shift from formal school activities and work to housing. With the addition of this activity, the residence must be able to be used functionally and meet comfort for the smooth running of activities in it. The purpose of this study is to identify, describe, and interpret changes in the function of space in residential areas as an adaptation process during a pandemic. The research method used is qualitative with purposive sampling. This qualitative research was conducted inductively by observing and interviewing the research case. Data were taken purposively on 6 residential areas in Jakarta, Depok, Bogor, Tangerang, and Bekasi. The results of this study are changes that occur in residential spaces in the form of non-physical changes, namely by adding activities that are accommodated in the space. Physically the space has not changed, this shows that the non-physical changes that occur are an adaptation process carried out by residential users. The adaptation process that occurs begins with adjusting activities to the available space in the dwelling. In the process of adaptation that occurs will choose a room that has the character as the need for new activities during the pandemic. In the end, housing can provide a positive response to the COVID-19 pandemic with flexibility in the use of space to accommodate new functions.
International Collaborative Experiences to Design Areas Prone to Flood: Intervention in the Southern part of Resistencia (Argentina)
Authors: Schneider Valeria , Roibón María José , Valenzuela María Victoria , Nogueira Julio Borges
Published: February 2022

The Brian A. Thomson Institute of Urban and Regional Planning of the Faculty of Architecture and Urbanism of the UNNE (Argentina) and the Jurusan Arsitektur Fakultas Teknik, Faculty of Engineering, Universitas Muhammadiyah Jakarta (Indonesia), have been developing joint activities within approved projects since 2015, as part of a framework of International Cooperation Agreement. Faced with the global context situation due to the Covid19 pandemic, where virtual activities flourished, it was considered an opportunity to bring together teams from both institutions in a joint activity. Therefore, an "International Workshop on Landscape 2020" was formulated to find better design schemes to mitigate the flood in the Southern area of Resistencia city in Argentina by implementing sustainable strategies to design flooding parks for recreational and absorbent purposes. With highly satisfactory outcomes prepared jointly by groups of students from both geographies, with the follow-up of coordinating Lecturers (Facilitators) and the participation of Keynote Speakers, a compendium was made for the formal transfer to the Local authorities, fostering the link between the academic spheres and society through a university extension mechanism. This article aimed to describe the collaborative work process, analyze the implemented methodologies, and lecturers and students' perceptions of this experience.
Corrigendum to “Augmented reality marker-based technology for augmenting newspaper advertisement"
Authors: Pervez Rahat , Chowdhury Diba , Sagor Md. Sahadat Hossain , Hoque Md. Imdadul , Islam Nafiul
Published: February 2022

Recent Research in Science and Technology, 2021, 13, 13–18. https://doi.org/10.25081/rrst.2021.13.7005One of the authors’ (Md. Imdadul Hoque3) affiliations was mentioned incorrectly. It should be read as follows:
3Department of Computer Science and Telecommunication Engineering, Noakhali Science andTechnology University, Noakhali – 3814, Bangladesh
Símbolos de descenso e intimidad en el arte infantil
Authors:   Universidad de Sevilla (España), León-Río María Belén
Published: February 2022

Art would set in motion the imagination of the plastic creator, bringing to light from consciousness a series of symbolic images related to the descent that are usually accompanied by symbols of intimacy as protectors on this journey into our essential being. These artistic productions would be created from the primordial experience of the artist whose nature would be expressed through mythological figures that would function unconsciously and that would help us discover other parts of our psyche where certain theologies would operate, which would demonstrate that these symbolic representations would have concomitances with the manifestations of human spiritual activity studied in ethnological research. In this article we will see which are these archetypes that emerged from the depths of the psyche through children’s artistic activity, proving how these images would have a great influence on our life since they would constitute symbols of transformation that would harmonize our consciousness.
Gráfica fuera de los límites: hacia una xilografía de campo expandido
Authors:   Escuela Universitaria de Diseño, Innovación y Tecnología (España), Santín Álvarez Eva , Navarro Goig Gema ,   Universidad Complutense de Madrid (España)
Published: February 2022

Printmaking is currently undergoing an unprecedented renewal, as a result of a contemporary printmaking’s updating process, driven not only by new techniques and technologies but also by an interdisciplinary approach. On the other hand, there are some artists working under the purest techniques who are focusing on strategies that question traditional printmaking’s foundations, heading towards an expanded understanding of printing that breaks with the established limits: redefinition of the series, experimentation with alternative supports, overcoming the two-dimensional plane towards graphic installation, hybridization and trans-disciplinarity, etc. Digital technologies have barged into the printmaking field, making new tools and work strategies available to the artist, saving time and achieving greater technical improvement. These qualities are producing changes on how we understand woodblock printing, both in the way of conceiving the artwork and in the technical execution of it.
Las algas coralinas (Rhodophyta) ante la acidificación del océano con especial referencia a las Islas Canarias
Authors:   Universidad de La Laguna, Afonso-Carrillo Julio
Published: February 2022

La futura acidificación de los océanos tendrá un impacto generalizado en las especies marinas y los ecosistemas. Las algas coralinas (Corallinophycidae, Rhodophyta) son elementos conspicuos de las comunidades litorales en todas las latitudes. En la pared celular de las algas coralinas interviene la forma más soluble de calcita, lo que las hace particularmente vulnerables a variaciones en el pH del mar. En esta síntesis discutimos el actual conocimiento sobre las algas coralinas de Canarias en el contexto de los avances producidos en las últimas décadas tanto en la taxonomía (aplicación de diferentes criterios taxonómicos) como en la ecología (un grupo de organismos que prestan unos servicios ecosistémicos muy valiosos). En Canarias las algas coralinas están actualmente representadas por 56 especies, pero existen fundadas razones para creer que es una subestimación del número real de especies. Participan en la mayoría de las comunidades litorales y su abundancia permite considerarlas como elementos característicos de numerosos hábitats, algunos de ellos escasamente investigados.
Percepção dos pais e responsáveis sobre o uso do canabidiol em crianças e adolescentes com epilepsia
Authors: Araújo Claudirene Milagres , Almeida Flávia Andrade , Rio Maria Luísa do Espírito Del , Silva Priscila Aparecida Ferreira da , Ferreira Brisa Emanuelle Silva
Published: February 2022

Objetivo: Compreender a percepção dos pais ou responsáveis sobre o uso do Canabidiol em crianças e adolescentes com epilepsia.  Métodos: Trata-se de pesquisa exploratória, descritiva, com abordagem qualitativa, onde os sujeitos foram captados pela estratégia “bola de neve” através do WhatsApp e responderam a entrevista pelo Google Forms por meio de questionário semiestruturado. Para avaliar os conteúdos dos depoimentos foi realizada análise temática proposta por Bardin L (2011). Resultados: Participaram da pesquisa 16 pais ou responsáveis. Segundo os sujeitos entrevistados, o Canabidiol pode atuar na melhora cognitiva, motora e melhor interação social o que proporciona melhora na qualidade de vida. Relatam também, alguns entraves na aquisição da substância como alto custo, dificuldades na importação e desconhecimento médico. Conclusão: Foi possível ter a percepção através do relato dos pais sobre a efetiva melhora através do uso do Canabidiol, mas o acesso ao medicamento ainda é um entrave. É de suma importância que o profissional enfermeiro se atualize em relação as possibilidades terapêuticas existentes para trabalhar junto aos pacientes e equipe multidisciplinar nos diversos níveis de atenção primário, secundário e terciário. Desta forma estudos com rigor metodológico devem ser conduzidos para apoiar a eficácia da utilização, verificar efeitos adversos, comprovando sua segurança.
Cuidado em saúde prestado às mulheres em situação de rua
Authors: Rocha Amanda Pinheiro Magalhães , Freitas Maria Yaná Guimarães Silva , Almeida Vivian Ranyelle Soares de , Nascimento Diana Cardeal do , Moura Jenny Caroline Vieira , Silva Juliana Macêdo dos Santos , Carvalho Dailey Oliveira , Silva Igor Rafael Souza da , Dias Jamille Soares , Mendonça Geisiane de Almeida
Published: February 2022

Objetivo: Descrever o cuidado em saúde prestado às mulheres em situação de rua, pela equipe do Consultório na Rua de uma cidade do interior da Bahia. Métodos: Trata-se de um estudo de natureza qualitativa com caráter descritivo e exploratório, em uma base operacional da equipe do Consultório na Rua em uma cidade do interior da Bahia, local onde os profissionais compartilham as experiências buscando desenvolver da melhor forma suas ações. A coleta de dados foi realizada através de observação passiva, analisada conforme a técnica de Bardin, além de entrevista semiestruturada no período de janeiro a fevereiro de 2020. Resultados: Os profissionais relataram as ações que são desenvolvidas para as mulheres de acordo com o preconizado pelo protocolo do serviço, como: a efetuação de palestras, testes rápidos, vacinação, exames, dentre outros. Foi explanado ainda, sobre a vacinação ser realizada como ação de impacto. Conclusão: A partir do estudo, conclui-se que é necessário um aumento nas estratégias de redução de danos no cuidar de mulheres em situação de rua, ofertando a elas serviço de qualidade, respeito aos seus direitos sexuais e reprodutivos, proteção à saúde mental, fortalecimento do convívio social, orientação sobre direito à alimentação, moradia, segurança, dentre outros.
EVALUASI SISTEM INFORMASI KEUANGAN UNIVERSITAS NEGERI SEMARANG DENGAN PENDEKATAN DELONE DAN MCLEAN
Authors: Kafrawi Slamet , Firmansyah Riza , Hartono Rudi , Budiman Kholiq
Published: February 2022

Sistem Informasi Keuangan (Sikeu) merupakan sistem yang penting bagi pengelola keuangan
 dalam menatausahakan proses bisnis keuangan serta membantu Unnes dalam meningkatkan kinerja
 pegawai, pertanggungjawaban, pengambilan keputusan manajemen, dan keterbukaan keuangan. Sikeu menjadi sistem sangat penting dan vital bagi keberlangsungan proses pengelolaan keuangan pada Unnes. Penyajian laporan keuangan yang reliabel sangat tergantung pada keberhasilan penggunaan Sikeu. Perlu adanya pengukuran dan evaluasi dari sistem informasi yang telah diterapkan, sehingga dapat diketahui sejauh mana optimalisasi dari penggunaan Sikeu tersebut. Selain itu agar memperoleh masukan untuk peningkatan kualitas sistem yang lebih baik. Populasi dalam penelitian ini adalah pegawai pada bagian/subbagian keuangan sebagai pengguna Sikeu yang meliputi Bendahara Pengeluaran, Bendahara Pengeluaran Pembantu Operator Sikeu dan Staf Pengelola Keuangan. Penelitian ini menggunakan data primer yang merupakan data penelitian yang diperoleh langsung dari sumber aslinya melalui kuesioner. Variabel independen dalam penelitian ini yaitu variabel Kualitas Sistem, Kualitas Informasi dan Kualitas Pelayanan, sedangkan variabel dependen meliputi Kepuasan Pengguna dan Kinerja Individu. Penelitian ini menggunakan pendekatan Partial Least Square (PLS) dalam proses analisis data. Berdasarkan uji hipotesis, dari empat hipotesis hanya tiga yang diterima. Hipotesis yang diterima meliputi kualitas informasi terhadap kepuasan pengguna Sikeu, kualitas layanan terhadap kepuasan pengguna Sikeu, dan kepuasan pengguna sikeu terhadap kinerja individu. Hipotesis yang ditolak adalah kualitas sistem tidak berpengaruh terhadap kepuasan pengguna Sikeu

 
PENGARUH KEUNGGULAN SISTEM OPERASI SMARTPHONE DAN LAYANAN PURNA JUAL TERHADAP KEPUASAN DAN LOYALITAS PELANGGAN YANG DIMODERASI OLEH KUALITAS PRODUK
Authors: Yani Ari Soeti , Aslamiyah Diah Nur
Published: February 2022

Penelitian ini bertujuan untuk menjelaskan pengaruh kualitas produk dan keunggulan bersaing
 terhadap keputusan pembelian dengan citra merek sebagai variabel intervening di era globalisasi milenial ini. Unit analisis dalam penelitian ini adalah para pemuda ataupun pemudi pengguna Smartphone IOS ataupun Android yang keren dan high class. Populasi dalam penelitian ini adalah mahasiswa Fakultas Ekonomi dan Bisnis Universitas 17 Agustus 1945 Jakarta. Metode pengambilan sampel dalam penelitian ini dilakukan dengan menggunakan purposive sampling, sebanyak 100 orang dengan menggunakan Rumus Slovin.Alat analisis statistic yang di gunakan dalam penelitian ini menggunakan PLS.3 yang digunakan untuk menguji hipotesis. Berdasarkan uji statistik, hasil penelitian menunjukkan bahwa Celebrity Endorser berpengaruh secara signifikan terhadap Kepuasan dan loyalitas pelanggan, keunggulan system operasi smarthphone tidak berpengaruh secara signifikan terhadap kepuasaan dan loyalitas pelanggan, Diferensiasi Produk berpengaruh secara signifikan terhadap Kepuasaan pelanggan terhadap kualitas produk. Moderasi Diferensiasi Produk berpengaruh tidak signifikan dan bersifat memperlemah pengaruhkeunggulan system operasi smarthphone terhadap kepuasaan pelanggan. Moderasi Diferensiasi Produk berpengaruh tidak signifikan dan bersifat memperlemah pengaruh Keunggulan system operasi smartphone layanan purna jual terhadap kepuasan dan loyalitas pelanggan

 
Platform Google Earth Engine Untuk Pemetaan Suhu Permukaan Daratan Dari Data Series Modis
Authors: Prayogo Luhur Moekti
Published: February 2022

Urban Heat Island (UHI) merupakan faktor yang mempengaruhi suhu permukaan bumi. Fenomena UHI menyebabkan suhu permukaan daratan kota lebih tinggi karena faktor antropogenik. Indentifikasi suhu permukaan daratan yang disebabkan oleh UHI dapat dilakukan dengan teknik penginderaan jauh berbasis cloud. Penelitian ini bertujuan untuk memetakan suhu permukaan daratan wilayah pesisir utara Surabaya dan sekitarnya dengan citra multi temporal MODIS tahun 2001-2020 menggunakan Platform Google Earth Engine. Lokasi tersebut dipilih karena diduga mengalami peningkatan suhu akibat aktivitas pembangunan yang umumnya juga terjadi di seluruh wilayah Indonesia. Dari penelitian ini dapat disimpulkan bahwa terjadi peningkatan panas yang cukup signifikan dari tahun ke tahun. Di pesisir utara Surabaya, Jawa Timur, pada tahun 2001 suhu permukaan pada kisaran 30oC terletak dibagian utara. Pada tahun 2011 suhu meningkat dan menyebar ke wilayah bagian selatan. Kemudian suhu paling tinggi ditunjukkan pada tahun 2020, dimana hampir keseluruhan wilayah memiliki panas diatas 28oC. Dari penelitian ini dapat diketahui bahwa penggunaan platform Google Earth Engine efektif untuk pemetaan suhu permukaan daratan. Perlu adanya penelitian lanjutan mengenai penggunaan data yang diukur langsung di lapangan dan citra resolusi spasial lebih tinggi agar mengetahui akurasi yang dihasilkan dari platform Google Earth Engine.
PERBEDAAN MODEL OHLSON, MODEL TAFFLER DAN MODEL SPRINGATE DALAM MEMPREDIKSI FINANCIAL DISTRESS
Authors: Widiasmara Anny , Rahayu Henny Catur
Published: February 2022

The purpose of this study is to provide empirical evidence that there are differences in the Ohlson, the Taffler and the Springate Model in predicting financial distress for companies listed on the Indonesia Stock Exchange in 2015-2017. The population in this study are all nine industrial sector companies listed. This study uses secondary data from annual financial reports / annual report in 2015-2017. Testing the hypothesis in this study using the normality test and the Kruskal Wallis test (different test). The results showed that the Taffler model is the model that has the highest level of accuracy in predicting financial distress conditions of companies listed on the Stock Exchange with an accuracy rate of 83.93%, then the Springate Model with an accuracy rate of 54.91% and the Ohlson Model which is a model with the lowest accuracy rate is 6.70%.
Keywords: Ohlson Model, Taffler Model, Springate Model, Financial Distress
Pengaruh Koneksi Politik terhadap Penghindaran Pajak
Authors: Khoirunnisa Asadanie Nabila , Venusita Lintang
Published: February 2022

This study aims to examine the effect of political connection on tax avoidance. The sample in this study were manufacture companies from the BEI for the periode 2015-2017. The sample were selected using purposive sampling technique and obtained a sample of 55 companies. The analysis technique used in this study is multiple linear regressions analysis using IBM SPSS Statistic program 23. The result of the study show that political connection has a negative effect on tax avoidance.
Keywords: political connection, tax avoidance.
Content analysis of the nature of science on elementary thematic textbooks 2013 curriculum
Authors: Jaenudin Irfan , Aisyiah Pratiwi Nur , Suryani Rani , Widodo Ari
Published: February 2022

The 2013 curriculum thematic learning book is used as the primary textbook in thematic learning in elementary schools. This study aims to describe the Nature of Science (NOS) content in the book. This study used a descriptive quantitative research design with the research objects are thematic learning textbooks for 2013 curriculum elementary school students from grades 1-6. Data were collected through observation techniques using a research instrument that contains the analysis of the aspects of the NOS. The data are analyzed through grouping, scoring, determining the validity and reliability, then describing and drawing conclusions. The results showed that the level of content of the NOS in the thematic learning books of the 2013 curriculum elementary school students was 12%, so that it could be categorized as significantly less. These data illustrate that the aspects of the NOS in thematic books already exist but have not been fully presented explicitly, correctly, entirely, and consistently.
Peningkatan Kompetensi Pedagogik dalam Melaksanakan Melaksanakan Blended Learning pada Guru SDN 1 Tugu Mlarak Ponorogo
Authors: Sutrisni Sutrisni , Sudarmiani Sudarmiani , Nugraha Nurhaji
Published: February 2022

Penelitian ini bertujuan untuk mengetahui peningkatan kompetensi pedagogik dalam melaksanakan blended learning mupel IPS melalui supervisi edukatif kolaboratif secara periodik guru SDN 1 Tugu Kecamatan Mlarak Kabupaten Ponorogo. Metode penelitian yang digunakan adalah pendekatan deskriptif kualitatif. Jenis peneltian ini adalah Penelitian Tindakan Sekolah (PTS) partisipan. Subyek peneltian ini adalah guru kelas 1 sampai dengan kelas 6 di SDN 1 Tugu. Teknik pengupulan data pada peneltian ini menggunakan observasi, wawancara dan dokumentasi. Validitas data menggunakan menggunakan reduksi data, data display dan conclusion drawing. Secara individu guru dinyatakan mampu apabila memperoleh hasil monitoring 71-85 dan dinyatakan sangat mampu apabila mendapatkan hasil monitoring sebesar 86-100.  Sedangkankan ketuntasan secara klasikal kompetensi pedagogik dalam melaksanakan blended learning mupel IPS pada pra siklus dari enam guru tidak ada guru dengan kriteria tuntas (0%), pada siklus 1 ada dua guru kriteria tuntas dan empat guru belum tuntas (33%), dan pada siklus 2 semua guru tuntas (100%). Hasil monitoring dan evaluasi pembelajaran luring, daring, tatap muka terbatas dan pengamatan pedagogik pada siklus 2 sudah di atas skor/ hasil monitoring ≥80 sehingga penelitian ini cukup sampai dua siklus.
Methods for Characterizing Polymer Surfaces and Interfaces
Authors: Russell Thomas P.
Published: February 2022

The behavior of polymer molecules at surfaces and interfaces has been receiving a considerable amount of attention over the past few years. Numerous developments have been made theoretically using simulations and analytic approaches. Experimentally, advances have been made in the development
of new techniques and the use of old techniques not commonly used in the investigation of polymers to probe the interfacial and near surface behavior of polymers. In this article, some of the experimental developments that have been made recently will be discussed. The approach will be to
focus on the behavior of thin films of diblock copolymers and diblock copolymers at the interface between immiscible polymers, describing the different techniques used to study these problems.
L-2-Amino-3-phosphonopropionsäure (AP-3): ein bedeutendes Phosphor-Analogon der L-Asparaginsäure
Authors: Vock Carsten A.
Published: February 2022

Im Artikel werden didaktisch nützliche Informationen zu Eigenschaften, (Bio)synthese und Anwendungen der L-2-Amino-3-phosphonopropionsäure (AP-3) zusammengestellt. Das Material ist zur Ergänzung chemischer Grundlagenvorlesungen im Hochschulbereich, aber ggf. auch für spezialisiertere Unterrichtseinheiten gedacht und einsetzbar.
Mass Spectrometry: An Essential Tool for the Flavor and Fragrance Industry
Authors: Begnaud Frédéric
Published: February 2022

Over the past decades, mass spectrometers have become standard instruments in the analytical laboratories of the flavor and fragrance (F&F) industry. As the expansion of the fields of use of flavors and fragrances and the launch of numerous new technologies designed to enhance their performance have led to a diversification and increased complexity of the questions asked to the analytical chemists, mass spectrometry remains an essential tool to address them. The capabilities of the latest generation of  instruments combined with advanced molecular separation and data processing tools allow to tackle many of these challenges. Through different examples, and focusing on the period that followed our 2014 review [1], this article illustrates different ways MS is contributing to the discovery development and commercialization of F&F ingredients and technologies, for both volatile and non-volatile molecules.
BASIC DETERMINANTS IN INTEGRATED SUPPLY CHAINS
Authors: Mindur Maciej , Pawęska Marcin
Published: February 2022

An integrated supply chain is currently a decisive factor when it comes to remaining on increasingly demanding markets. Optimal organization of the supply chain is often a serious challenge for businesses that need to function in a more efficient way, and to provide products tailored to individual customers' needs. The accuracy and precision at every stage are crucial, as well as shorter response time to changes in demand, customer tastes and economic conditions.
Analysis of relationships between drivers’ perception of road infrastructure in Poland and their involvement in road accidents and collisions
Authors: Sendek-Matysiak Ewelina
Published: February 2022

Road accidents and collisions are very common in Poland and, although for the last several years their number has been constantly decreasing, it is still one of the highest in Europe. This article attempts to provide an answer to the question whether drivers’ overrating the changes in the Polish road transport infrastructure might contribute to the status quo – the factor that has so far been left uninvestigated. In [21], the authors demonstrate that drivers take notice of the changes and perceive them as changes for the better.
Designing of Functional Areas of Intermodal Terminals
Authors: Pyza Dariusz , Jachimowski Roland
Published: February 2022

This article is about the design of intermodal terminals. The classification of intermodal terminals and their role in the transport chain were presented. Particular attention has been paid to the design of functional zones of the intermodal terminal serving both containers as well as swap bodies and semi-trailers. Technical and technological requirements for these zones were determined. Theoretical example of calculation of selected functional zones of intermodal terminal is presented.
Modeling Quality Assessment of the Supply Chains
Authors: Jóźwiak Arkadiusz , Zelkowski Jarosław , Świderski Andrzej
Published: February 2022

The article presents how to use methods and tools in the area of quality engineering to assess the supply chain, having the example of the food industry. It outlines the regulatory requirements and standardization documents for the transport of dairy products. Using a questionnaire conducted it selects criteria that were directly used to assess the quality of the supply chain (network). Then, using the Pareto-Lorenz diagram the most important criteria were selected, which were also used in the study.
The Impact of Brexit on the Transport Industry
Authors: Kerridge Martin
Published: February 2022

By referendum on 23 June 2016, voters in the United Kingdom of Great Britain and Northern Ireland voted narrowly to leave the EU. The vote was called for party political reasons, as the ruling Conservative party was divided on the issue of continued EU membership, and the Government expected that a national pro-EU popular vote would silence those who wanted to leave. When the result turned out to be the opposite of what the Government expected, the Prime Minister resigned, despite an earlier pledge that he would abide by and implement the result. The new Prime Minister – who had voted to remain in the EU – repeated the pledge, even though the referendum had been an advisory, not a binding, one. The subsequent period has been spent in trying to achieve an agreement that minimises the adverse socio-economic consequences, to both sides, of a UK departure from the EU, prior to the declared leaving date of 29 March 2019. This paper examines likely effects of Brexit on the transport industry. It starts by explaining the meaning of Brexit, the timetable for UK exit, and some of the possible reasons why the referendum vote turned out as it did. (There has been a surprising lack of research into this subject, and none was undertaken by the UK Government in the aftermath of the vote.) The paper then considers the possible trade and commercial alternatives that the UK has to EU membership. ‘Norway’ or ‘Canada’ (or Canada Plus) arrangements were part of the internal discussion in the UK in the period after the referendum (which had not included a question on alternatives). A UK Government insistence (‘red line’) that the UK would no longer be subject to the jurisdiction of the European Court of Justice, which interprets EU law, limited the options available to the UK. The possible consequences to the UK, if it leaves the EU without a mutually acceptable withdrawal agreement, are then considered. Having set the background to this possible event, the paper then looks at how it may affect the transport industry. All modes of transport, other than inland waterway transport which has no direct connection between the UK and other EU countries, are examined. In each case new agreements will be needed to avoid serious disruption in the event of a ‘no-deal’ Brexit that removes the UK from the single market and customs union, with the UK then being regarded as a third country for trade and transport links. The final part of the paper examines the likely effect of Brexit on the economies of the UK and the remainder of the EU (and hence transport demand). It finds that Ireland may be the most affected EU country, but that the economy of the remaining EU-27 as a whole will suffer as a result of Brexit. After Ireland, the UK economy will be hit hardest, and we may never know if that is a result that the ‘leave’ voters in 2016 expected or not.
The competitiveness of small Baltic container terminals. The PROMETHEE II multi-criteria analysis
Authors: Bartosiewicz Aleksandra , Szterlik Paulina
Published: February 2022

The article examines the competitiveness of small Baltic container terminals. In order to conduct the research, thirty terminals, whose annual maximum throughput capacity does not exceed 150,000 TEU, have been examined taking into consideration a number of criteria which are: length of the quay (C1), number of RTG (C2) and STS (C3) cranes, number of shortsea shipping connections (C4), maximum (technical) depth at the quay (C5), distance from motorways and expressways/national roads (C6), distance from the national railway station (C7). Selected k=7 criteria were used to perform PROMETHEE II (Preference Ranking Organization Method for Enrichment Evaluations II) multi-criteria ranking that enabled specifying those Baltic Sea container nodes which are in the area of strategic benefits for the analysed market sector.
Emergency Evacuation Route Choice Based on Improved Ant Colony Algorithm
Authors: Wang Bo , Guo Lin , Zhou Jibiao , Ristvej Josef , Jánošíková Michaela
Published: February 2022

In order to explore the optimal route choice for emergency evacuation in the campus, we propose a novel route choice method based on brittle characteristics of campus system and improved ant colony algorithm. Both optimal and worst-case emergency evacuation routes are simulated in the campus of Ningbo University of Technology. From the simulation, the length of optimal and worse-case evacuation routes between the starting point and eight exits can be obtained by adjusting the importance value of trip distance and the degree of conformity, under the condition of static relative importance of pheromone concentration to graph G. The optimal route of emergency evacuation in the campus can be obtained when the importance of trip distance is above 5 and the degree of conformity is above 0.3; while the worse-case route is obtained with the importance of trip distance above 5 and the degree of conformity below 0.5.
Assembly of π-Conjugated Helical Peptides into a Porous and Evolvable Protein-like Lattice
Authors: Heinz-Kunert Sherrie , Pandya Ashma , Dang Viet Thuc , Tran Phuong Nguyen , Ghosh Sabari , McElheny Dan , Santarsiero Bernard , Ren Zhong , Nguyen Andy
Published: February 2022

The evolution of proteins from simpler, self-assembled peptides provides a powerful blueprint for the design of complex synthetic mate-rials. Previously, peptide–metal frameworks using short sequences (≤ 3 residues) have shown great promise as proteomimetic materials that exhibit sophisticated capabilities. However, their evolution has been hindered due to few mutable residues and restricted choice of side-chains that are compatible with metal ions. Herein, we developed a non-covalent strategy using π-stacking to assemble much longer peptides into crystalline frameworks that tolerate even previously incompatible acidic and basic functionalities, and allow an unprecedent-ed level of pore mutations. Single-crystal X-ray structures are provided for all mutants to guide and validate rational design. These materi-als exhibit hallmark protein behaviors such as guest-selective induced-fit and assembly of multi-metallic units. Significantly, we demon-strate facile evolution of the framework to substantially increase affinity towards a complex organic molecule.
Late-stage functionalization of glucosides and aminoglycosides to combat bacterial resistance
Authors: guo tianyun , yan xiaoxiao , cao haonan , lu lei , gao lina , tang shouchu , liu jian , wang xiaolei
Published: February 2022

The rapid emergence of resistant bacteria and the scarcity of antibiotic pipeline has been a persistent threat to the global health. To expand the antibiotic pipeline, we have focused our strategy by revitalizing the current antibiotic via novel site-specific derivatization. Aminoglycosides (AGs), once considered effective therapeutics for treating clinical infections, are now seeing limited use due to drug-induced toxicity and AG-resistant bacteria. Challenges in synthesis and modifications of AGs impedes their potential for re-gaining efficacy. Here we discuss a photoredox catalyzed late-stage modification of glucosides including AGs. Our chemistry can selectively install an alkyl group at the 3- position of unprotected glucoside with a broad substrate scope and high yields. Among the products, we characterized a series of compounds that can overcome drug resistance caused by APH (3’) and one of them achieved 30-fold potency compared to kanamycin against sensitive strains. The chemistry we describe here opens a new avenue for discovering new AGs antibiotics that overcome drug resistance and may also serve as the basis for understanding their SARs.
Synthesis and styrene copolymerization of novel dimethyl and dimethoxy ring-substituted isobutyl phenylcyanoacrylates
Authors: Cimino Alessandra , Camacho Ehxciquiel M. , Evans Samantha M. , Garza Daniela , Gregory Dylan A. , Petrescu Julia C. , Rocha Margaux J.E. , Scannell Brian J. , Schreck Katelyn M. , Zuljevic Mikal , Rocus Sara M. , Schjerven William , Kharas Gregory B
Published: February 2022

Novel dimethyl and dimethoxy ring-disubstituted isobutyl phenylcyanoacrylates, RPhCH=C(CN)CO2CH2CH(CH3)2 , where R is 2,3-dimethyl, 2,4-dimethyl, 3,5-dimethyl, 2,3-dimethoxy, 2,4-dimethoxy, 2,5-dimethoxy, 2,6-dimethoxy, 3,4-dimethoxy, 3,5-dimethoxy were synthesized by the piperidine catalyzed Knoevenagel condensation of ring-disubstituted benzaldehydes and isobutyl cyanoacetate and characterized by CHN analysis, IR, 1H and 13C NMR. The acrylates were copolymerized with styrene in solution with radical initiation (ABCN) at 70C. The compositions of the copolymers were calculated from nitrogen analysis and the structures were analyzed by FTIR, 1H and 13C NMR.