bluuebunny/crossref_metadata_2025 huggingface dataset:
Hypertension: Care Management Program and Medication Adherence
Authors:   , Montgomery Courtney
Published: July 2023

Practice Problem: Medication adherence is a major concern in healthcare as it is a contributing factor to uncontrolled hypertension and resistant hypertension. Uncontrolled hypertension can lead to strokes, heart attacks, kidney failure, and even death. PICOT: The PICOT question that guided this project was in Medicare Advantage members with hypertension located in Kansas, who were admitted to the hospital or emergency room identified by stratification (P), does care management utilization using hypertension clinical guidelines (I), compared to the stand-alone hypertension clinical practice guideline (C), improve medication adherence (O) over 10 weeks (T)? Evidence: Hypertension is one of the leading preventable causes of death. Medication adherence is around 50% in half of individuals diagnosed with hypertension and annual cost of unnecessary visits for hypertension is in the billions. A care management program is a cost-effective way to help individuals with a chronic condition manage their health and medications, decreasing the rate of complications. Intervention: A care management program utilizes medical professionals to assist members with chronic diseases, such as hypertension, to become more knowledgeable and autonomous with their healthcare. This program provides members with support in ensuring medications are taken and their chronic condition is being monitored to prevent complications and unnecessary emergency room and re-hospitalization visits. Outcome: There was a lack of data due to the lack of participant participation, therefore, no blood pressure data was collected. The emergency room visits or re-hospitalization, including financial reports, were not available. Medication adherence percentages did not show any clinical significance. Conclusion: It was difficult to assess clinical significance due to lack of data at the closure of this pilot program.
AN ASSESSMENT OF PERSISTENT ORGANIC POLLUTANTS (POPS) INDICATOR LEVELS IN DRINKING WATER FROM MUBI-NORTH, GIREI AND MAYO-BELWA LOCAL GOVERNMENT AREAS IN ADAMAWA STATE
Authors: Kabiru A. M.
Published: July 2023

The assessment of persistent organic pollutants (pops) indicator levels in drinking water from Mubi-north, Girei and Mayo-belwa local government areas in Adamawa was carried out in three sampling point for each local government. A total of 63 samples were collected during the rainy season in August- October 2018 and during the dry season, 63 samples were equally collected from January- March 2019. Composite sampling method was employed and the samples Areas were coded, labelled, sealed and preserved. Analog grade reagents were used throughout. The water samples collected were analyzed using standard procedures. Generally, the respective values of POP recorded during the rainy season are higher than their value recorded in dry season both in well and borehole water, across the three Local Government Areas. The analysis of variances on the differences among persistent organic pollutants recorded during rainy and dry season across the respective well and borehole water in the three selected Local Government Areas are significant difference at p<0.05. however, all the POPs recorded both in the rainy and dry seasons across the well and borehole water were within the tolerable limits of 1μg/l for human consumption and 0.5μg/l for children toys set by FEPA and EU.
SOLVOTHERMAL SYNTHESIS AND CHARACTERIZATION OF TEREPHTHALIC ACID-BASED METAL-ORGANIC FRAMEWORKS AND THEIR CATALYTIC APPLICATION IN BIODIESEL PRODUCTION
Authors: Odu C. O. , Obunwo C. C. , Bull O. S.
Published: July 2023

Metal-Organic Frameworks (MOFs) are a class of porous crystalline materials, consisting of metal ions or nodes linked with organic ligands. The study was aimed at solvothermal synthesis and characterization of terephthalic acid-based Metal-Organic Frameworks and their catalytic application in biodiesel production. Three MOFs of Cu-, Fe-, and Cr-based were solvothermally synthesized, characterized and applied as catalysts in biodiesel production using ethanol and oil extracted from Yellow Oleander seeds. The MOFs were synthesized using terephthalic acid as the linker and copper (II), iron (III) and chromium (III) nitrates as metal ion sources. Each of the synthesized MOFs showed high melting point exceeding 360 oC. Microscopic view and powder X- ray diffraction analysis indicated Cu-MOF to be crystalline with numerous sharp peaks while those for Fe- and Cr-MOFs were amorphous. A comparison of the FT-IR spectra of the ligand and those of the MOFs confirmed the presence of the ligand in the synthesized MOFs. In the absence of a catalyst, the transesterification was not achieved. However, in the presence of the more crystalline Cu-MOF as catalyst resulted to high yield (83.33%) and in a shorter time compared to the less crystalline Fe- (33.33%) and Cr- (25.00%) MOFs. Thus, catalytic ability of the MOFs were in the order: Cu-MOF > Fe-MOF > Cr-MOF. Hence MOFs especially Cu-MOFs can be applied as catalyst in biodiesel production. Further studies and characterization (single X-ray diffraction) should be done for proper elucidation of the crystal structure of the MOFs.
INVESTIGATION OF THE IMPACT OF POTENTIALLY TOXIC ELEMENTS FROM URBAN FLOODED AREAS IN PORT HARCOURT CITY, NIGERIA
Authors: Amaibi P. M. , Maduelosi N. J. , Lekia S.
Published: July 2023

Flooding transports significant environmental contaminants in soils especially potentially toxic elements (PTEs). The prevalence of PTEs in the environment poses serious threat to human health. Anthropogenic activities contribute to elevation of PTEs contents in soils. In this study, a total of 24 soil samples collected from six study areas within Port Harcourt city were analysed to determine level of some elements (As, Cd, Cr, Pb and Ni) following the acid digestion methods. Samples were taken from different soil profiles ranging from topsoil (0 – 30 cm) to sub-soil (30 – 60 cm). Each sample was subjected to three acid digestion procedures namely: aqua regia, reversed aqua regia and multi-acid attack. For purposes of quality control, levels of the elements of interest in the digested samples along with blanks were measured using atomic absorption spectrometer (AAS). A wide range of total concentrations of the toxic elements was found, with high level of concentration obtained in the topsoil. The proportion of elements released by the multi- acid attack method was higher than those of aqua regia and reversed aqua regia methods. This finding suggests that the heavy metals bound to silicate minerals are not easily dissolved in simple mineral acids. A correlation analysis revealed a strong association between Pb and total organic carbon (r = 0.950012), indicating that the source of Pb contaminants may be derived from organic matter contents. The potential health risk associated with PTEs indicated non-carcinogenic risk for children and carcinogenic risk for adults living in the flooded areas. Further monitoring of flooded areas in Port Harcourt metropolis is recommended for other environmental contaminants beside the PTEs monitored.
EXTRACTION AND TRANSESTERIFICATION OF OIL FROM PALM KERNEL CATALYSED BY 10%H2SO4 AND 10%NaOH MODIFIED CLAY MATERIALS
Authors: Leke L. , Ogah M. E. , Weor T. T. , Okopi S. O. , Undo T. T. , Orhena E. S.
Published: July 2023

Biodiesel production has gained prominence owing to the menace of climate change believed to be caused majorly by fossil fuel combustion. The heterogeneous transesterification option is regularly employed considering its enormous advantages. This research sampled abundant and locally available and renewable materials; palm kernel (for extraction of oil) and clay (employed as a catalyst). The clay was calcined at 400 oC, modified using 10 % by weight H2SO4 and NaOH respectively, characterised by BET and X-ray diffraction and then used for transesterification with the extracted palm kernel oil to produce biodiesel in a 1: 9 oil to methanol ratio and 10 % catalyst dosage of the acid (H2SO4) and alkali (NaOH) modified clay respectively. The results show biodiesel yields of 66.67 % and 73.33 % respectively. The physicochemical characterisation of the biodiesels obtained had values that conformed with ATSM values for good biodiesel, while their GC-MS analyses confirmed the presence of many fatty acid methyl esters which are responsible for biodiesel production. X-ray diffraction and BET analyses respectively showed crystallinity and presence of some minerals with surface area (65.52 – 72.43 m2g-1), pore size (0.997 Ao) and pore volume (24.54 – 28.04 cm3/g) for the clay. These abundant environmentally friendly biofuels that are economically produced, show very good prospects of replacing fossil fuels.
INVESTIGATION INTO THE PESTICIDES RESIDUES IN SESAME, MILLET, RICE, AND GUINEA CORN GROWN AROUND THE HADEJIA-KOMADUGU-YOBE RIVER AREA IN YOBE STATE, NIGERIA.
Authors: Shettima S A , Gashinge A M , Baffa A A , Akinlabi A K , Abdulkadir A S
Published: July 2023

Application of pesticides during crop production often results in pesticide residue, a significant source of heavy metals in the harvested crops. This raises concern for consumers' health due to the potentially deleterious effects of pesticides on animals, particularly humans. This study examined the levels of pesticide residues using a gas chromatography-mass spectrometry (GC-MS) system and heavy metal elements concentration using Atomic Absorption Spectrometry (AAS) in four food crops (Sesame, Millet, Rice, and Guinea corn) cultivated in (Gwio-Kura) Gashua and Hadejia towns in Nigeria. The results disclosed that Sesame was the only crop with Dichlorvos from both Gashua and Hadejia, surpassing the WHO's limit for pesticide residue concentrations, and that the Hadejia samples had higher levels than the Gashua samples. The study also detected traces of Cadmium (Cd), Lead (Pb), Nickel (Ni), and Manganese (Mn) in the crops, but they were below the permissible intake levels established by FAO/WHO. However, Arsenic (As) and Chromium (Cr) exceeded the FAO/WHO limits and may entail serious health problems such as kidney damage and cancer. Mercury (Hg) was not detected in any of the crops. Our findings suggest health authorities monitor and regulate heavy elements intake in food crops, especially those with high toxic contamination, to prevent adverse health effects such as the kidney disease on humans and animals, currently prevalent in the area.
COMPARATIVE RISK ASSESSMENT OF SOME TOXIC ELEMENTS’ CONTENTS IN DOMESTIC AND IMPORTED TOMATO PASTES AND KETCHUP IN NIGERIAN MARKETS
Authors: Oladapo F. O. , Awokoya J. O. , Egbedeyi T. D.
Published: July 2023

Although tomato consumption, whether as tomato paste or tomato ketchup, offers several health advantages, the future prognostic indicators hypothesize the disappearance of these gains due to heavy metal poisoning. Therefore, using the Microwave Plasma Atomic Emission Spectroscopy (MP-AES) technique, this study examined and compared the amounts of arsenic (As), nickel (Ni), cadmium (Cd), lead (Pb), and mercury (Hg) in locally produced and imported tomato pastes and ketchup sold in Nigerian markets. The mean concentrations of these targeted elements in tomato pastes and ketchup (in mg.kg-1) respectively are presented as follows: As (domestic & imported: < LOQ), Ni (domestic:0.308, 0.289; imported: 0.271, 0.267), Cd (domestic:0.088, 0.075; imported:0.078, 0.083), Pb (domestic: 0.121, 0.102; imported:0.128, 0.136) and Hg (domestic and imported: <LOD). As, Ni, and Cd contents in domestic and imported tomato pastes and ketchup samples and daily intake rates (DIR) were within acceptable levels recommended by regulatory agencies. Except when combined metals’ hazard quotients are considered, which may pose serious health concern, individual’s metal effect constitutes a negligible health risk.
INVESTIGATION OF THE EFFECT OF DIFFERENT SOLVENT RATIOS IN THE CHEMOMETRIC PHYTO-EXTRACTION AND IN-VITRO SCREENING OF Carica papaya FRUIT, USING RESPONSE SURFACE METHODOLOGY [RSM]
Authors: Ike-Amadi. C. A. I , Nwabue F. I. , Ekea-John K. , Nworie F. S.
Published: July 2023

Carica papaya plant is a popular medicinal plant with notable anti-parasitic potentials. This work reports chemometrics of the three solvents [petroleum ether, chloroform and methanol] in the in-vitro screening of Plasmodium falciparum and Trypanosome brucei b. The Response Surface Methodology [RSM] method based on a second order and three variables Box-Behnken Design (BBD) was employed to obtain the optimal combination of extraction conditions. The extraction process parameters of the fruit of Carica papaya were optimized by BBD so as to get maximal yield of bio-actives. Different solvent ratios were used to achieve different response optimized by chemometric. For the in-vitro screening of Plasmodium falciparum and Trypanosome brucei b., the extracts of Carica papaya fruit were subjected to assay procedures to see their viability. Summarily, the 3D response surface plot and the contour plot derived from the mathematical models were applied to determine the optimal conditions. Under the optimized conditions, the experimental value of 77.97% viability on Plasmodium f. was in close agreement with the value predicted (77.97 ± 0.01 %) by the model and 82.86 ± 1.10%was predicted for Trypanosome brucei b. with an experimented value of 83.48%; showing close correlation between the predicted and experimental values. Considering RSM studies, it was found that the mixture of petroleum ether, chloroform and methanol solvents at a ratio of 55 mL: 27.50 mL: 17.50 mL gave an optimum viability on the in-vitro screening. Hence, the polarity of solvent affects the yield of bioactive compounds in the plant material.
A Literature Review: Challenges of Internationalization in Small and Micro Enterprises Medium (SMEs)
Authors: Nurul Khaerani Siti , Sudarmiatin Sudarmiatin , Sumarsono Hadi
Published: July 2023

This article aims to find out the challenges faced by SMES in entering international markets. The methodology in writing this article is literature review. And limited to articles related to field studies. The search results found several articles with the specified keywords. Some of the challenges faced by SMEs in entering international markets in several countries such as Fiji, Nigeria, India, Nepal, Bangladesh, Finland and Sweden in entering international markets include access, both access to limited knowledge of international markets, access to finance, geographical conditions, and several other challenges. It is hoped that this article will provide benefits for finding solutions in facing the challenges of SMEs in facing the international market.
Factor Analysis Of Rejection Of Covid-19 Vaccination In Rural And Urban People Communities In Langkat Regency In 2022
Authors: Claudia Khalisa , Khairunnisa Khairunnisa , Wiryanto Wiryanto
Published: July 2023

Coronavirus is one of the diseases with the fastest transmission rate that is currently disturbing the world. One alternative that could be done to anticipate this complaint was to administer a vaccine as an antidote to this virus. The purpose of this study was to determine the factors contributing the rejection of Covid -19 vaccination in rural and Urban communities in Langkat Regency in 2022. The research method used in this research combined quantitative methods and qualitative methods. With a total sample of 260 people divided into 2 groups (rural and Urban comunity, the number of samples in Urbancomunity areas was 130, and the number of samples in rural community areas was 130. The results of this study indicated that the community's rejection of vaccines was caused by several factors, namely anxiety about side effects (an average of 15.37 ± 2.494 for rural communities) and fear of being injected. 13.42 ± 2.539 for rural communities that had never been vaccinated and 13.75 ± 3.419 for Urban people, rejection of community leaders as much as 13.42 ± 3.452 for village people; doubts about vaccine halalness as much as 14.88 ± 2.698 for Urban people; fake news for about 14.68 ± 2.904 for Urban people, did not believe in the virus 12.93 ± 3.216 for people in cities, and the uncertainty of the vaccine program as much as 12.71 ± 2.997 for Urbanpeople. From the results of the analysis, it could be seen that the largest level of rejection was carried out by Urban people communities.
Antibacterial Activity Of Lime Peel (Citrus Aurantifolia (Christm.) Swingle) Ethanolic Extract Against Skin Infection Bacteria (Propionibacterium Acnes And Staphylococcus Epidermidis)
Authors: Sormin Novia , Arianto Anayanti , Pandapotan M.
Published: July 2023

The skin is the outermost part of the body that serves as a protective body. In addition to protecting the skin of the face, it also acts as a beautifier. The main problem with facial skin is inflammation of the skin, which can cause acne. Bacteria like Propionibacterium acnes, Staphylococcus aureus, Staphylococcus epidermidis, and Pseudomonas aeruginosa can cause acne on the face. Prolonged use of antibiotics as therapy against acne will cause a new problem, namely resistance to antibiotics. Lime peel has many uses, especially as an antibacterial, which makes it a good candidate for use as an antibacterial agent in acne treatment. The goal of this study was to find out if the etTMhanolic extract of lime peel could kill bacteria like Propionibacterium acnes and Staphylococcus epidermidis. The research method used the Kirby-Bauer method and the Streaking methods to analyze the minimum inhibitory concentration and minimum bactericidal concentration. The results showed MIC at a concentration of 1 mg/mL for each bacterium, while MBC at a concentration of 40 mg/mL in Propionibacterium acnes and 50 mg/mL in Staphylococcus epidermidis. The conclusion is that the extract of lime peel in ethanol can kill bacteria.
Application Of The Utmost Good Faith Principle In Life Insurance Business Management In Indonesia
Authors: Ashri Maunah Nur , Sunargo Bambang , Puspitaloka Mahadewi Erlina
Published: July 2023

The study focused on the purpose of this writing is to find out the application of the principle of utmost good faith in life insurance. The research method used in this study is to use data collection methods in library research or library research. In this literature study the author obtains the materials and library materials needed by studying books, writings, journal citations and statutory and legal products that are related to the subject matter according to topics in Indonesia so that it can be concluded that: first, legal principles in insurance coverage include insurable interest, utmost good faith, indemnity principle, subrogation principle, causaliteit principle, contribution principle, cause principle, follow of fortune. Second, the types of risk in insurance are pure and speculative risk, diversifiable and non-diversifiable risk, company risk, systemic risk, financial and non-financial risk, individual and group risk, static and dynamic risk. Third, the application of the principle of utmost good faith in life insurance is very important, because if there is submission of information and information that is incorrect, it can result in the insurance agreement being cancelle.
A Study of Managed Care Health System During Pandemic
Authors: Ayu Gebyar , Fermansyah Hari , Puspitaloka Mahadewi Erlina
Published: July 2023

The present study reports the comprehensive study on managed care during the pandemic, regarding to the cases of the covid-19 outbreak increased every day, even reaching 2,000 cases per day in Indonesia. The surge in the cost of handling covid-19 patients and delays in payment of covid-19 claims by the Indonesian Ministry of Health have worsened the situation and the handling of the quality of services by health service providers. For this reason, the role of managed care is needed in these conditions. The purpose of this study is to analyze and find out the pattern and course of managed care in Indonesia by comparing it with several countries that have also been infected with covid-19. This research method is a literature review study with an online database search strategy or search engine in the form of related research journals from the year 2020-2023. The results obtained by researchers are the lack of health human resources, medical devices and "pandemic fatigue" which are problems that contribute to the course of managed care in almost every region in Indonesia. The role of society and government policies affect the overall implementation of managed care programs. When the community complies with the policies that apply in the pandemic era and the government provides policies in collaboration with health experts. Managed care program one of prospective plan for Indonesia healthcare industry development in the future.
Application Of Consumption Method With Eoq, Mmsl Forecasting And Abc-Ven Analysis In Pharmaceutical Briefing Management In Hospitals General Royal Prima Marelan
Authors: Afni Kartika Ajeng , Girsang Ermi , Wienaldi Wienaldi , Novalinda Ginting Chrismis
Published: July 2023

Hospitals should plan for drug needs using accountable methods to avoid empty drugs. Good drug planning can improve pharmaceutical stock control in hospitals. The purpose of this study was to find out about the application of consumption methods with EOQ, MMSL and ABC-VEN forecasting in the management of pharmaceutical supplies in hospitals. This study used retrospective mix-method data, quantitative data and qualitative primary data. The research was conducted at RSU Royal Prima Marelan. The results showed that drug supply control using the EOQ method of getting drugs reordered: cefixime 200MG ordered at 447, ondacetron 4MG 740, gabapentin 300MG 706, ranitidine 25MG 1467, novorapid flexpen / 5" 42. In the SS method, the number of drugs available at delivery, cefixime 200MG should be 627 drugs at the time of shipment, ondacetron 4MG should be 522, gabapentin 300MG should be 470, ranitidine 25MG should be 940, and novorapid flexpen/5" should be 26. In the ROP method the drug was reordered at cefixime 200MG it was reordered when the stock was 447 and the quantity ordered was 12027, ondacetron 4MG 740 and 10000, gabapentin 300MG 706 and 9020, ranitidine 25MG 1467 and 18040, novorapid flexpen 42 and 502. In the ABC method, group A as many as 59 types 70.59% with a total investment of 70.59% drug use and an investment value of IDR 606,511,106, group B 64 drug investment 20.33% investment 20.33% drug use investment 174,722,327, group C 146 types (9.08%) investment 9.08% drug use and investment 78,028,263.
Analysis of Relation Between Risk-Based Work Breakdown Structure (WBS) on Integrated Design and Construction Works of Design and Build Contract on Mechanical and Electrical Works of High Rise Building for Improving Safety Performance
Authors: Feronica Damanik Mariana , Latief Yusuf , Nugroho Danang Budi
Published: July 2023

The construction industry has had the highest accident rate worldwide for decades. Identifying risks as early as feasible during the pre-construction or design phase is essential to preventing construction accidents. To generate a structured list of risks, a Work Breakdown Structure (WBS) is used to identify risks. Although numerous studies have proposed using Work Breakdown Structure (WBS) to identify risks, no one has analyzed the relationship between Work Breakdown Structure (WBS) and risk to reduce construction accidents. Consequently, this study aimed to investigate the impact of Work Breakdown Structure (WBS) risk during the design and construction phases on construction safety performance. The analysis of relationships will be conducted using statistical methodologies. The study's findings will demonstrate that Work Breakdown Structure (WBS) risk affects construction safety performance.
Islamic Social Reporting (ISR), Sharia Supervisory Board (SSB), and Financial Performance: Empirical Evidence on Islamic Banks in the GCC Region
Authors: Iskandar Rizkiana , Marlina Lilis , Urna Fasihat Dian
Published: July 2023

This study aims to determine the relationship between the disclosure of Islamic social reporting (ISR), the Sharia Supervisory Board (SSB), and the financial performance of Islamic banks in the Gulf Cooperation Council (GCC) region. The Islamic banks that were the sample of the study totaled 25 banks spread across Bahrain, Kuwait, Qatar, Saudi Arabia and the United Arab Emirates with a sample period starting from 2013 to 2017. This research uses multiple regression testing and is complemented by content analysis. The results of content analysis show that the average level of ISR disclosure in Islamic banks in the GCC area is 56.53%. That is, the issues of social responsibility have not become a major concern for most Islamic banks. Furthermore, based on the test results, the ISR disclosure level proved to have a positive effect on financial performance. In addition, the existence of SSB in Islamic banks is also proven to have a positive association with financial performance which is proxied by return on average assets. These findings indicate that there are special things in Islamic banking such as disclosure of ISR and SSB that can have a good impact on the financial performance of Islamic banks.
Phytochemical Screening And Antidiabetic Test Of Ethanol Extract Of Turmeric Leaves (Curcuma domestica Val.) On Decreasing Blood Glucose Of Diabetic Rats
Authors: Br Turnip Nur Ulina M , Harahap Urip , Hasibuan Poppy Anjelisa Z.
Published: July 2023

The turmeric plant (Curcuma domestica Val.) is a tropical plant that grows a lot on the Asian continent with is use as a food coloring and fragrance. The use of turmeric leaves by residents is only a cooking ingredient not used in large quantities. Even most of these turmeric leaves are considered waste and have minimal utilization. Turmeric leaf methanol extract can be used to lower blood glucose. Turmeric leaf extract has the potential as a valuable food source of its antioxidant components, such as total phenolic compounds and flavonoids which increase radical scavenging activity. In particular, the water extract of turmeric leaves contains high total phenolic compounds (2.741 ± 0.099 mg GAE/g) and flavonoids (4.776 ± 0.010 mg QCE/g). Diabetes mellitus is a metabolic disorder associated with several chronic complications, such as nephropathy, neuropathy, retinopathy and cardiomyopathy. Part of the turmeric plant leaves is reported to have the ability as an antioxidant. Antioxidant compounds can control blood glucose levels and prevent diabetes complications. This study was conducted to test the ability of turmeric leaf ethanol extract (EEDK) to reduce blood glucose levels in diabetic rats induced by nicotinamide and streptozotocin and to perform phytochemical screening to determine the compounds contained in turmeric leaves so that it becomes an alternative as a diabetes treatment and can prevent damage. or diabetic complications. The results showed that turmeric leaves contained secondary metabolites, namely flavonoids, glycosides, tannins, and triterpenoids/steroids, but there were no alkaloids or saponins. The characterization results show that the sample meets the requirements. Turmeric leaf ethanol extract doses of 400 mg/kg, 200 mg/kg, and 100 mg/kg could reduce the Blood Glucose Level of NA and STZ-induced rats from the fourth day of treatment.
Phytochemical Screening And Test For Reducing Uric Acid Levels In Male Rats After Administration Of Ethanol Extract Of The Herb Binara (Artemisia vulgaris L.)
Authors: Situmorang Novidawati Boru , Harahap Urip , Hasibuan Poppy Anjelisa Z.
Published: July 2023

Hyperuricemia is a metabolic disease generally characterized by high uric acid levels in the blood. The general treatment strategy for hyperuricemia is to decrease uric acid production using xanthine oxidation reductase inhibitors such as allopurinol and uricosuric agents. However, the drugs showed side effects, including skin rashes, diarrhoea and liver damage. To overcome the side effects of synthetic drugs, alternatives are used, namely by researching to find plants that have activity in reducing uric acid levels. The activity of reducing uric acid levels in plants is likely due to the presence of flavonoid compounds as antioxidants. Flavonoids active in reducing uric acid levels are kaempferol through xanthine oxidase inhibitors. Quercetin also has the potential to reduce uric acid levels through inhibition of the xanthine oxidase enzyme. Binara plant (Artemisia vulgaris L.) has flavonoids, tannins, alkaloids, glycosides and saponins which have potential as antioxidants and analgesics, anti-inflammatory, immunomodulating, and hepatoprotective, through secondary metabolites of flavonoids, terpenes, and phenolic acids. The Karo people have traditionally used Binara leaves to treat wounds, diarrhoea and heartburn by chewing some of the leaves and then placing them on the wounds outside the body, such as cuts and for diarrhoea and stomach ulcers and placing them around the sick stomach. This study was conducted to know the anti-hyperuricemia effect of the Ethanol Extract of Herba Binara (Artemisia vulgaris L.) on gout rats; phytochemical screening was carried out first to determine the content of Herba Binara (Artemisia vulgaris L.) compounds. The results showed that Herb Binara fulfilled the simplicia characterization requirements and contained secondary metabolites such as alkaloids, flavonoids, tannins, glycosides, saponins and steroids. Herb Binara Ethanol Extract has been shown to reduce uric acid levels in hyperuricemia rats, with the best concentrations being 400 and 800 mg/kg body weight. This was based on significantly different results p>0.05 compared to the positive control group.
Do high-performance Employee influenced Work Motivation and Compensation in a Corporations?
Authors: Hakim Adi Lukman , Faizah Erna Nur
Published: July 2023

Companies depend more on their workforce than just suitable facilities and advanced equipment to achieve their goals. To achieve organizational goals, human resources - particularly employees - play an important role. This study aims to explain how the relationship between work motivation, compensation, and employee performance; how these factors affect employee performance; and which component has the most influence on employee performance. A total of 35 employees were involved in this study. The method used was the total sampling method. To collect information, surveys and interviews were conducted. Scale range and multiple linear regression were used as analytical techniques to assess and validate the research hypotheses. Employee performance has a positive impact on the company. The same results also show that work motivation and compensation have an effect on the success of the company, employee performance increases when incentives and work motivation are improved. This implies that work motivation and compensation have a positive influence on employee performance.
Phytochemical and FTIR Analysis Of Coriander Leaf Infusion As An Active Pharmaceutical Ingredient
Authors: Wulandari Suci , Sinaga Siti Morin , Harahap Urip
Published: July 2023

This study reported that the sample used in the study was an infusion using fresh coriander leaves samples taken in the Lubuk Pakam area. Several studies have shown that the active components of coriander seeds are essential oils such as sabiene, myrcene, alphaterpine, ocimene, linalool, graniol, decanal, desilaldehyde, trantridecen, petroselinic acid, octadesenic acid, d-mannite, scopoletin, psimena, kamfena and felandren. These components cause coriander to have a good effect as a medicinal component. In previous studies, Linalool is believed to have antioxidant, anxiety, antibacterial (especially gram-positive) and antifungal effects. This activity is suspected because coriander contains secondary metabolites such as alkaloids, saponins, flavonoids, tannins, steroids, triterpenoids, glycosides. So this research was conducted to determine the content of secondary metabolites in coriander leaves by phytochemical screening. Phytochemical screening is a test to determine the class of chemical compounds present in coriander leaf infusion samples. Fourier transform infrared spectroscopy (FTIR) analysis was performed to find the isolating compounds in coriander leaves. The results showed that one secondary metabolite compound was negative in examining steroid secondary metabolites. The results of extract assistance with FTIR showed the presence of saponins with a molecular weight of 873.0 g/mol at a retention time of 19,287 minutes, but the peaks produced were not dominant.
Evaluation Of Information System Governance Capability Level Of Engineering Construction Services Firm Using Cobit Framework 5
Authors: Adi Nugroho Winsu , Sutomo Rudi
Published: July 2023

Engineering Construction Services Firm Instrument Engineering is a company in engineering construction services. Not only construction services Engineering Construction Services Firm Instrument Engineering also has services in the field of non-construction such as operation and maintenance. There is no quality management standard in the company expected to increase productivity and superiority over competitors; the company needs a schedule to conduct periodic audits of information security management. It requires recommendations for improving the Information Security Management System), and the company hopes to make a standard document for data and information security risk governance aimed at supervision and review of the Information Security Management System. To make sure that SI operations within the Company have been carried out and objectives have been supported as effectively as possible, it is required to conduct an information system audit using the Control Objectives for Information and Related Technology (COBIT) framework based on the needs that have been described. The research on evaluating IT governance abilities using the COBIT 5 framework APO13 process ends at level 1 with a status of 82.12. EDM03 and APO12 processes terminate at level 2, with a Largely achieved status of 82.12 for EDM03 and 84.41 for APO12.
Antibiofilm Formation Activities of Ethanol Extract of Curcuma domestica Val. Rhizome Against Multidrug-resistant Acinetobacter baumannii
Authors: Nasution Halimah Raina , Yuandani  , Abdi Wira Septama  , Sony Eka Nugraha  , Sufitni
Published: July 2023

Abstract.

 

Multidrug resistance is still a major health problem worldwide. Biofilm formation was related to the resistance of bacteria mechanism. Acinetobacter baumannii, one of the bacteria that cause nosocomial infections, is given particular attention due to its high prevalence of resistance. The current study address observing the antibacterial activity and antibiofilm formation activity of Curcuma domestica rhizome extract against multidrug-resistant Acinetobacter baumannii (MDR A.baumannii). Curcuma domestica rhizome was macerated by ethanol 96%. Determination of Minimum Inhibitory Concentration (MIC) was carried out by the microdilution method. Antibiofilm formation analysis was determined by standard quantitative using crystal violet-stained assay. Ethanol extract of C. domestica possesses antibacterial activity against MDR A. baumannii with MIC value 250 µg/mL. Additionally, the ethanol extract of C. domestica could inhibit the biofilm formation of MDR A.baumannii, thus percentage of biofilm formed only 23.7% and significance different with control after analyzed using ANOVA post hoc test Tukey. According to these results, ethanol extract of C. domestica revealed antibacterial activity and had the potency in suppressing the biofilm formation of MDR A.baumannii, thus could be utilized in clinical application, especially in MDR A.baumannii infection.

 

Keywords: Antibiofilm, antibacterial, Curcuma domestica, multidrug-resistant, Acinetobacter baumannii
The Influence Of Service Quality Dimensions On Customer Loyalty With Customer Satisfaction As An Intervening Variable
Authors: Ramadhani Jatmika M. , Abdurrahman Agus
Published: July 2023

This study aims to determine the effect of the dimensions of service quality on customer  loyalty at the coffee shop, with customer satisfaction as the intervening variable. The  research method used in this study is a quantitative method by giving questions to a number  of respondents using a questionnaire on the form (google form). The results of this study  show that the responsiveness and empathy variables have a direct and significant influence  on customer satisfaction at the Laju Coffee shop and this study also proves that the customer  loyalty at Laju Coffee Shop is also influenced by the customer satisfaction.
Management Orthopedic Patient With Covid 19, A Picture Of Patient Safety
Authors: Luh Tantri Ni , Fauzi Mahmud , Rohman Rohman , Rochma Erwi , Isnaini Berry , Dwi Retno
Published: July 2023

This study will describe management policies to maintain hospital services by putting safety and analyze epidemiological data on orthopedic patient with covid-19 infection who were admitted during covid-19 pandemic. A retrospective descriptive study of orthopedic patients with covid-19 infection profile during 1st wave of covid-19 Pandemic  (January - March 2021). Modification of patient and staff work flow were also made, based on risk of transmissions, this include rescheduling elective surgery and promoting telemedicine. For patient who were admitted for urgent surgery, transition room were made for screening covid-19 infection before operation, there also a negative pressure operation room for patient who need an emergency operation. There were 38 orthopedic patients admitted to transition room, 18  patient (47.36%) were confirmed covid-19 infection. There are slight fewer female patient with confirmed Covid-19, compare to the male patient  8 (44.4%)  vs  10 (55.6%) patient. The Patient’s age ranged from 5 to 79 years old, with average of 46.27 years old (SD 20.63). With most  patient were 56-65 years old. The patients’ diagnosis and demographics data were described in table 1. Five  patients (27.8 %) with mild covid-19, nine patients (50 %) with moderate covid-19 and four patients (22.2 %) with severe covid-19. Among 18 patients with confirmed covid-19, seven  patients  (38.9%) had  hypertension and three patients(16.7%) had diabetes . The Laboratory data shows 13 patients (72.7%) had abnormal NLR with all patients had  increased D Dimer. Average length of stay were 12.78 days, Range 2 days to 21 days; SD 5,53) with eleven patients (61.1%) underwent operation procedure and 7 (38.9%)  patients were on conservative treatment. There was 1 (1.8%0 death case recorded, among patients with confirmed COVID-19, this was a C3 Spinal Cord Injury patient with tetraplegia and respiratory failure. During this period there were 16 (2.5% from 636 staff) were diagnosed with covid-19, among them  60% in red area ( operation room, Emergency unit, polyclinics, isolation room and laboratory). There were no documented in hospital death among orthopedic patient with confirmed covid-19 who underwent surgery procedure. Covid-19 had disrupted many aspects in hospital services. Our Hospital had develop new policies and strategies to minimize covid-19 transmission during the 1st wave covid-19 pandemic. Preoperative screening, proper personal protective equipment’s, and strict transmissions control successfully minimize covid-19 transmission in our hospital. Orthopedics patient with Covid-19 infection, that require urgent surgery were admitted to isolation room. Prompt treatment  according  to WHO Guideline were given.
Effect Of Seft Giving (Spiritual Emotional Freedom Technique) On The Level Of Anxiety Of Covid 19 Patients In The Edelweis Isolation,Orthopedic Hospital Prof. Dr. R. Soeharsosurakarta
Authors: Rochma Erwi , Rohman Rohman , Ansori Wahid , Aiyanto Ferry , Muthmainah Qowiyatul , Dewi Suciningtyas Putri
Published: July 2023

Coronavirus Disease (covid-19) is a disease caused by the Severe AcuteRespiratory Syndrome Coronavirus-2(SARS-COV-2) virus. Coronavirus Disease(covid-19) has become a worldwide pandemic. This study aims to determine theEffect of Giving SEFT (Spiritual Emotional Freedom Technique) Regarding the Anxiety Level of Covid-19 Patients in the Edelweis Isolation Ward, Prof. Orthopedic Hospital. Dr. R. Soeharso Surakarta. Thisresearch is a quantitativestudy, with the experimental method of one group pre and post test design (withoutcontrol group), which is done to reveal causal relationships or influences by involving one group of subjects.This research was conducted on 30 respondents in the Edelweis Isolation Ward, Prof. Orthopedic Hospital. Dr. R. Soeharso Surakarta, with female sex as much as 60% and the most age range 45-55 years asmuch as 36.7%, most jobs are private as much as 20% and most education is S1 as many as 33.3%. Respondents with comorbidities were 43.3% and 23.3% were patients with pneumonia. From the results of the analysis using the Wilcoxon test, the p-value = 0.00001 (<0.05). There is an effect of giving SEFT (Spiritual EmotionalFreedom Technique) therapy on the anxiety level of Covid-19 patients in the Edelweis ward of Prof.Orthopedic Hospital. Dr. R. Soeharso Surakarta.
Development Of Risk-Based Work Breakdown Structure (WBS) Standards For Integrated Design And Construction Phase On Design-Build Method Of Architectural Works Of High-Rise Building To Improve Construction Safety Performance
Authors: Andina Ganesdhi Gabby , Latief Yusuf , Budi Nugroho Danang
Published: July 2023

Design-build methods are one of the options in carrying out the construction of high-rise buildings with a high level of uncertainty from design phase to construction, which also affects the safety performance of the project itself. Therefore, a prevention standard for a high-risk event is needed based on project activities. This research was prepared using a descriptive qualitative method with expert validation process through Delphi method and completed with a questionnaire survey to conduct a risk assessment. The output in this research is a development of risk-based standard work breakdown structure for architectural work, which generated from 39 high level risk. Based on the results of the mapping of preventive and corrective actions at high-level risks, 5 types of WBS development can be carried out at levels 3 to 6 of the WBS to prevent and minimize the impact of risk so that safety performance could be improved. The novelty in this research lies in the form of design-build project delivery activities which has not been widely discussed in previous work breakdown structure research and risk identification based on the activities listed on the WBS.
Indonesia's Marine Economic Potential As A Maritime Country
Authors: Hastuti Hastuti , Muhidu Amiruddin , Rastin Rastin , Agus Mokodompit Eliyanti
Published: July 2023

This nation has economic potential that is no less flashy and dazzling in terms of natural resources and the environment. The main purpose of this article is to emphasise the importance of Indonesia's marine economic potential as a maritime country in achieving Indonesia's prosperity and glory as a maritime country. Fisheries, marine tourism, marine transportation, offshore energy and mineral resources, marine industry, marine buildings, and marine services are all goals for the marine economic spectrum. This marine resource's potential economic value is estimated to be at least $8.22 trillion per year. This article was written using qualitative and descriptive literature studies. A literature review was used as the research method to analyse the journal. Reviewing related libraries is what a literature review entails. (Review of related literature/review of literature) The findings indicate that the Indonesian government already has a policy in place for Indonesia's marine strategy, which refers to Indonesia's Development Vision, which is contained in Law Number 17 of 2007 concerning the National Long-Term Development Plan 2005-2025 and Law Number 32 of 2014 concerning Marine. This policy is reflected in a number of concepts, including Blue Economy, Maritime Domain Awareness, World Maritime Axis, and Nusantara Insight. To realise Indonesia as an independent, advanced, and strong archipelagic country based on national interests, this great potential must be managed and utilised holistically, integrated thematically, and distributed spatially proportionally through an integrated development planning process supported by harmonious spatial planning and the implementation of sustainable development that can run in harmony.
The Impact Of Product Quality And Service Quality On Consumer Satisfaction At Kedai Falsafah Ngopi Bogor, Indonesia
Authors: Ismartaya Ismartaya , Hikmat Maulana Lucky , Simanjuntak Wildaria , Kartini Tini
Published: July 2023

In the current era of globalization the business world is growing day by day so companies will not be separated from competition and are required to provide a good marketing system. The problem of product quality, service quality and customer satisfaction is the determining factor so it needs to be investigated. The sampling technique used was purposive sampling with a total sample of 60. The data collection technique used a questionnaire that had been tested for validity, reliability test, and classical assumption test. The data analysis method used was multiple linear regression analysis, correlation coefficient analysis, and coefficient of determination analysis. A hypothesis test was also conducted using the F test method and the t test. The results showed that simultaneously and partially product quality, service quality had a positive and significant effect on consumer satisfaction. It is recommended to evaluate to find information that makes consumers comfortable and satisfied.
PENINGKATAN MEMBACA UNTUK PERSIAPAN SEKOLAH DASAR MELALUI MEDIA READING WHEEL PADA KELOMPOK B DI TK ABA 2 PENDIL
Authors: Nur Azizah Ivo Sindia , Aini Nur , Adawiyah Robiatul
Published: July 2023

Abstrak Reading Wheel merupakan alat bantu ajar yang memudahkan anak untuk mengingat dan belajar, seperti permainan kincir, alat bantu ajar ini juga memberikan stimulasi kepada anak untuk menyukai atau lebih aktif mengidentifikasi suku kata dan belajar membaca dengan lebih mudah. , hasil belajar akan lebih bermakna bagi siswa kelompok B. Metodologi penelitian menggunakan penelitian tindakan kelas (PTK) untuk memahami peningkatan keterampilan membaca anak usia dini dengan kegiatan membaca roda pada kelompok Pendil B TK ABA 2 Kabupaten Banyuanyar Tahun 2022/2023.  Pada Penelitian Tindakan Kelas (PTK) ini dilakukan dalam 2 siklus, dari hasil tindakan yang dilakukan terbukti meningkatkan kemampuan membaca anak, yaitu pada siklus sebelumnya pada siklus I siklus 38,25% dapat ditingkatkan menjadi 61,25 %, siklus I meningkat lagi, dan siklus II mencapai 85,35%. Hasil penelitian tindakan kelas ini menunjukkan bahwa penggunaan media roda baca dalam pembelajaran dapat meningkatkan kualitas keterampilan membaca anak.Kata Kunci :   Membaca,media reading wheel, anak usia diniAbstrakReading Wheel is a teaching aid that makes it easier for children to remember and learn, such as a pinwheel game, this teaching aid also stimulates children to like or be more active in identifying syllables and learning to read more easily. , learning outcomes will be more meaningful for group B students. The research methodology uses classroom action research (CAR) to understand the improvement of early childhood reading skills with wheel reading activities in the Pendil B group of TK ABA 2 Banyuanyar Regency in 2022/2023. In this Classroom Action Research (CAR) was conducted in 2 cycles, from the results of the actions taken it was proven to improve children's reading skills, namely in the previous cycle in the first cycle of 38.25% the cycle could be increased to 61.25%, the first cycle increased again, and cycle II reached 85.35%. The results of this classroom action research indicate that the use of reading wheel media in learning can improve the quality of children's reading skills.Keywords : Reading, Reading Wheel, early childhood