bluuebunny/crossref_metadata_2025 huggingface dataset:
Insights About Cannabis and Psychosis Using Video Games for Young People With a First Episode of Psychosis, Particularly Those From Black Racialized Communities: Protocol for a Mixed Methods Study
Authors: Archie Suzanne , Palaniyappan Lena , Olagunju Andrew T , Johnson Natasha , Kozloff Nicole , Sadeh Elham , Bardell Andrea , Baines Alexandra , Anderson Kelly K , Ayonrinde Oyedeji , Ferrari Manuela
Published: April 2022

Background

Cannabis use disorder among young people with a first episode of psychosis contributes to relapse, hospitalization, and impaired functioning. However, few studies have examined what young people with early phase psychosis, particularly those from Black racialized communities, understand or appreciate about this relationship, even though they may be at risk. There are no formally tested knowledge translation strategies that disseminate these research findings for young people with emerging psychosis from Black racialized communities.

Objective

This study aims to conceptualize what young people with early phase psychosis/cannabis use disorder understand about the relationship between cannabis and psychosis, focusing on people from racialized backgrounds. This study also aims to assess whether the knowledge translation product, the “Back to Reality Series,” increases awareness of the impact of cannabis use on psychosis from the perspectives of young people with emerging psychosis and cannabis use disorder from Black African and Caribbean communities.

Methods

Qualitative analysis will reveal themes from qualitative interviews about cannabis and psychosis from the perspectives of young people with emerging psychosis and cannabis use disorder from Black African and Caribbean communities. Perceptions before and after exposure to the Back to Reality Series will be qualitatively analyzed. A control game will be used for comparison, and scores on a quiz after playing the Back to Reality Series will be quantitatively analyzed to establish whether the Back to Reality Series raises awareness of the effects of cannabis on psychosis. An advisory council involving young people from Black communities, family members, and clinicians will bring community perspectives to this research.

Results

We began recruiting participants for this study in September 2021. We will complete data collection on demographic and clinical factors, qualitative interviews, and quantitative assessments of the Back to Reality Series.

Conclusions

The voices of young people from racialized backgrounds will generate preliminary data to inform early psychosis programs, addressing cannabis use in this population. The findings may advance the use of a new knowledge translation product that deals with gaps in knowledge about cannabis use for people experiencing early phase psychosis, particularly those from racialized communities.

International Registered Report Identifier (IRRID)

DERR1-10.2196/36758
A Mobile-based Virtual Reality Speech Rehabilitation App for Patients With Aphasia After Stroke: Development and Pilot Usability Study (Preprint)
Authors: Bu Xiaofan , Ng Peter HF , Tong Ying , Chen Peter Q , Fan Rongrong , Tang Qingping , Cheng Qinqin , Li Shuangshuang , Cheng Andy SK , Liu Xiangyu
Published: April 2022

BACKGROUND

Stroke has the highest disability-adjusted life-years lost in any disease, and approximately one-third of the patients get aphasia. Computers and tablets are innovative and aid in intensive treatments in speech rehabilitation for patients with aphasia. However, mechanical training limits the help to patients.

OBJECTIVE

This study aims to provide a framework for an integrated virtual reality (VR) app to provide speech rehabilitation for patients with aphasia.

METHODS

The content was generated through an in-depth literature review and discussion with experienced rehabilitation physicians and occupational therapists. We then conducted a 2-round Delphi study with 15 experts from hospitals and universities to rate the content using a 5-point Likert scale. The app was developed by an interdisciplinary team involving VR, medical science of rehabilitation, and therapeutic rehabilitation. Pilot usability testing of this novel app was conducted among 5 patients with aphasia, 5 healthy volunteers, 5 medical staff, and 2 VR experts.

RESULTS

We designed 4 modules of speech rehabilitation: oral expression, auditory comprehension, cognition, and comprehensive application. Our VR-based interactive and intelligent app was developed to provide an alternative option for patients with aphasia. Pilot usability testing revealed user satisfaction with the app.

CONCLUSIONS

This study designed and tested a novel VR-based app for speech rehabilitation specifically adapted to patients with aphasia. This will guide other studies to develop a similar program or intelligent system in a clinical setting.
Psychological Health Matters: Content Analysis of COVID-19–Related Tweets Under Lockdown Policy in Saudi Arabia (Preprint)
Authors: Hamad Eradah
Published: April 2022

BACKGROUND

In these exceptional times stemming from the outbreak of the Coronavirus Disease 2019 (COVID-19), people are staying in their homes and following the precautionary social distancing measures that governments have announced. Social media networks—including Twitter, for example¬—are the perfect tools for communicating with others during the pandemic. With social media, people can send and collect information, as well as express their feelings about and reactions to what people are experiencing amid the unusual COVID-19 crisis. Exploring the content posted on these platforms may help with understanding the factors affecting the mental health of the general public at the present time, their future psychological immunity, and their physical health.

OBJECTIVE

This study aims to promote an understanding of the content that Arabic Twitter users shared on the platform between April and May 2020 in order to explore and describe people's opinions and feelings about the implications of the COVID-19 outbreak on their lives by identifying that content’s main and subthemes. The main objective of the study is to identify the most common content in a sample of tweets posted between April and May 2020 by Arabic Twitter users discussing the impact of the COVID-19 outbreak on their lives.

METHODS

To achieve the study’s goal, the researchers tracked and monitored people’s feelings and reactions through 1,100 tweets that were randomly collected through selected hashtags. The tweets were categorized based on their content into main and subthemes, using the qualitative content analysis methodology.

RESULTS

The findings showed that factors that influence mental health, such as anxiety, isolation, and feelings of fear and panic of infection, followed by COVID-19-related preventive instructions, constituted the most commonly shared content of the tweets, along with academic and career topics (e.g., long-distance study and work).

CONCLUSIONS

The analysis of the data will provide valuable information that governments and relevant organizations can use as an early warning system for better managing pandemics and other crises. This understanding may also help public health organizations to properly plan social media content and to disseminate the correct information regarding disease outbreaks and their effects on the world and local population.
Standardized Patients Creating and Evaluating a Global Assessment Measure for the Multiple Mini Interview: A Mixed Methods Study (Preprint)
Authors: Kennedy Ann Blair , Riyad Cindy Nessim Youssef , Ellis Ryan , Fleming Perry R. , Gainey Mallorie , Templeton Kara , Nourse Anna , Hardaway Gail , Brown April , Evans Pam , Natafgi Nabil
Published: April 2022

BACKGROUND

Standardized Patients (SP) are essential stakeholders in the Multiple Mini Interviews (MMIs) that are increasingly used to assess medical school applicants' interpersonal skills. However, there is little evidence for their inclusion in the development of instruments.

OBJECTIVE

This study aims to describe the process and evaluate the impact of having SP create a global measurement question that assesses medical school applicants’ readiness for medical school and acceptance status.

METHODS

This study used an exploratory sequential mixed-methods study design. A single question to measure readiness for medical school was collaboratively developed in a workshop by 21 SP, three Simulation Specialists, and two researchers. This question and the additional rubric items were evaluated through statistical tests based on applicant data. Internal reliability of the MMI was measured using a Cronbach’s alpha test and predicting admission status was tested using a forward stepwise binary logistic regression.

RESULTS

The evaluation of the developed rubric was assessed based on the 1,084 applicants across three cohorts. Cronbach's alpha was >0.8 overall and in each cohort year. The final stepwise logistic model for all cohorts combined was statistically significant (p < .001), explained 9.2% (R2) of the variance in acceptance status, and correctly classified 65.5% of cases. The final model consisted of three variables: Empathy, Rank of Readiness, and Opening the Encounter.

CONCLUSIONS

This study indicates that SP can effectively create a global question to evaluate applicants in the MMI. SP bring a critical perspective that can improve the admissions process for medical schools.

CLINICALTRIAL

none
The Sarcoidosis App: A national prospective study of quality of life and physical activity in 629 individuals with sarcoidosis using smartphones (Preprint)
Authors: Chu Brian , O'Connor Daniel M , Wan Marilyn T , Barnett Ian , Shou Haochang , Judson Marc A , Rosenbach Misha
Published: April 2022

BACKGROUND

Large gaps exist in understanding the symptomatic and functional impact of sarcoidosis. Smartphones could be used for prospective research, especially for rare diseases where organizing large cohorts can be challenging, given their near ubiquitous ownership and ability to track objective and subjective data.

OBJECTIVE

We investigate whether smartphones could assess quality of life (QoL) and physical activity of a large cohort of individuals with sarcoidosis.

METHODS

We developed a mobile application (“Sarcoidosis App") for prospective, cross-sectional study of individuals with sarcoidosis. Individuals were recruited, consented, and enrolled entirely within the App. Surveys of sarcoidosis history, medical history, and medications were administered. Patients completed modules from the Sarcoidosis Assessment Tool, a validated patient-reported outcomes assessment of physical activity, fatigue, pain, skin symptoms, sleep, and lungs symptoms. Physical activity measured by smartphones was tracked as available.

RESULTS

From April 2018 to May 2020, the App was downloaded 2,558 times, and 629 enrolled (64.2% female, mean age 51 years, 81.6% white, 13.7% black). Both QoL related to physical activity (p<0.001, ρ=0.250) and fatigue (p<0.01, ρ=-0.203) correlated with actual smartphone-tracked physical activity. Nineteen percent of participants missed at least one week of school or work in an observed month due to sarcoidosis, and 44% reported finances “greatly” or “severely” affected by sarcoidosis. Sixty-three percent reported medication side effects.

CONCLUSIONS

We demonstrate that smartphones can prospectively recruit, consent, and study physical activity, QoL, and medication usage in a large sarcoidosis cohort, using both passively collected objective data and qualitative surveys. Our study provides a model for future smartphone-enabled clinical research for rare diseases and highlights key technical challenges.
Pivotal Issues of Democratic Governance: A Literature Review
Authors: Pribadi Ulung , Iqbal Muhammad
Published: April 2022

Democratic governance has become a popular term to influence public sector reform in many countries. As a new governance theory, democratic governance has also gained significant interest from scholarly circles. Scholars had different perspectives when discussing the topic of democratic governance. Political perspectives examined democratic governance, especially in terms of states, regime, election and democracy. Technological perspective saw the importance of ICTs, social media, artificial intelligence and big data. The public administration perspective studied the importance of public policy, public management and local government institutions. There were rarely scholars who mapped the ideas about democratic governance. The study tries to fill this gap in thinking about democratic governance by reviewing the journal articles on democratic governance published in Scopus data based. Via NVivo analysis tools, this study showed five pivotal issues, including “government,” “public,” “policy,” “political,’ and ‘institutional.’ Besides, this study revealed some important sub-issues of the pivotal issues, covered ‘responsible government,” “representative government,” “government policy,” “public participation,” “public affairs,” “public interest,” “public policy,” “policy formulation,” “policy implementation,” “political participation,” “political actors,” “political authority,” “institutional change,” “institutional capacity,” “state institutions.’ This study also developed propositions from the pivotal issues and sub-issues. Furthermore, this study proposed a new theoretical model based on the propositions. Finally, this study acknowledges the weaknesses and suggests future research.
The Knowledge Assessment of Renal Transplantation (KART) 2.0
Authors: Waterman Amy D. , Nair Devika , Purnajo Intan , Cavanaugh Kerri L. , Mittman Brian S. , Peipert John Devin
Published: April 2022

Background and objectives

Many individuals with kidney disease, particularly those belonging to racial and ethnic minority groups and whose primary language is not English, lack knowledge related to kidney disease symptoms, physiologic functions of the kidney, and benefits and risks of kidney transplantation. Valid instruments to assess patients’ knowledge of CKD and kidney transplantation are needed.

Design, setting, participants, & measurements

Using a sample of 977 patients with stages 3–5 CKD in the Kaiser Permanente health system, we developed the Knowledge Assessment of Renal Transplantation (KART) 2.0 instrument. We conducted cognitive interviews followed by item response theory (IRT) to reduce 48 candidate items. Construct validity was tested by examining differences in scores between patients who spent <1 and ≥1 hour receiving CKD and transplant education.

Results

Cognitive interviews modified four items and omitted 11. IRT analyses resulted in two scales: the KART 2.0–Transplant Knowledge Scale (16 items; Cronbach’s α=0.8) and the KART 2.0–CKD Knowledge Scale (nine items; Cronbach’s α=0.79). Differential item functioning showed that the scales were unbiased to capture knowledge across self-identified race, primary language, CKD stage, and sex. Both scales distinguished patients who had spent <1 and ≥1 hour speaking with health professionals (effect size [ES]=0.33 [transplant], 0.54 [CKD]; P<0.001 for both), reading about kidney disease (ES=0.45 [transplant], 0.62 [CKD]; P<0.001), reading about kidney transplantation (ES=0.67 [transplant], 0.69 [CKD]; P<0.001), and reading about living donor kidney transplant (ES=0.76 [transplant], 0.62 [CKD]; P<0.001).

Conclusions

The KART 2.0 is a valid tool to assess patients’ knowledge of CKD and kidney transplantation.
Diseño e implementación de un prototipo de ajedrez controlado por voz mediante una aplicación móvil
Authors: Roman Gonzales Stanley Jinel
Published: April 2022

El recrearse con un juego de mesa como el ajedrez presenta muchos beneficios tales como el desarrollo cognitivo y emocional en los niños hasta la prevención de la enfermedad del Alzheimer en el adulto mayor, sin embargo, estos beneficios no están al alcance de las personas con deficiencia motriz ni en circunstancias en el cual 2 personas ajenas no pueden estar muy cerca. Debido a lo mencionado, se hace necesario el desarrollo de un dispositivo que aborde estas problemáticas. En este artículo se presenta el desarrollo de un prototipo alpha de un tablero de ajedrez cuyos trebejos son controlados por voz a través de una aplicación móvil y cuyo oponente se ubica remotamente. El diseño del prototipo consiste en una caja cuadrada de 38 cm x 38 cm x 7 cm donde en la parte superior se ubica el panel de tablero de ajedrez con los trebejos, internamente se localiza el manipulador cartesiano que desplaza los trebejos por todo el tablero y el sistema de control electrónico que está conformado por una serie de componentes de fácil reemplazo encargados de controlar y analizar los movimientos que realizan los trebejos en el tablero. Además, se cuenta con una aplicación móvil el cual tendrá la función de convertir la voz del jugador en una señal digital y enviarla hacia el controlador del tablero de ajedrez; asimismo brinda la opción de jugar de manera remota con alguna otra persona que posea el mismo tablero. Con el desarrollo del prototipo se pudo establecer los cimientos para posteriores mejoras. Se observó, por ejemplo, que puede incluirse otro modo de juego al agregar un sensor en el efector final del manipulador para que detecte si existe un trebejo en algún casillero.
LiDAR Based Self-Driving Car
Authors: Rane Vedant , Poojari Hrithik , Sharma Prasan , Phansekar Soham , Pawar Prof. Prajakta
Published: April 2022

LiDAR, typically used as an acronym for “’light detection and ranging’”, is essentially a sonar that uses pulsed laser waves to map the distance to surrounding objects. It is used by a large number of autonomous vehicles to navigate environments in real time. Its advantages include impressively accurate depth perception, which allows LiDAR to know the distance to an object to within a few centimetres, up to 60 metres away. It’s also highly suitable for 3D mapping, which means returning vehicles can then navigate the environment predictably —a significant benefit for most self-driving technologies. One of the key strengths of LiDAR is the number of areas that show potential for improvement. These include solid-state sensors, which could reduce its cost tenfold, sensor range increases of up to 200m, and 4-dimensional LiDAR, which senses the velocity of an object as well as its position in 3-D space. However, despite these exciting advances, LiDAR is still hindered by a key factor; its significant cost. LiDAR is not the only self-driving detection technology, with cameras as the major rival, championed by Tesla as the best way forward. Elon Musk has described LiDAR as “a fool’s errand” and “unnecessary”. The argument runs that humans drive based only on ambient visible light, so robots should equally be able to. A camera is significantly smaller and cheaper than LiDAR (although more of them are needed), and has the advantage of seeing in better resolution and in colour, meaning it can read traffic lights and signs. However, cameras have a wide host of characteristics that make them tricky to use in common driving conditions. Whereas LiDAR uses near infra-red light, cameras use visible light, and are thus more susceptible to issues when faced with rain, fog, or even some textures. In addition, LiDARs do not depend on ambient light, generating their own light pulses, whereas cameras are more sensitive to sudden light changes, direct sunlight and even raindrops
Role of Additive Manufacturing in Investment Casting Process
Authors: Sigirisetty Mohit
Published: April 2022

Abstract: The aim of this study was to describe systematically the best available evidence of Additive manufacturing (AM) technology for different casting paths and How Rapid Investment casting (RIC) is revolutionizing the field of casting. The objective of this systematic review is to investigate the capabilities and effectiveness of Additive Manufacturing to provide an effective solution for investment casting production. Google Scholar, ResearchGate, Mendeley, ScienceDirect databases are used for research purposes. The conventional method of Investment Casting is less effective in terms of cost and time to develop new hard tooling wax patterns for low volume production and prototypes. To overcome this problem, we introduced additive manufacturing for making patterns for investment casting. This paper reviews the specific applications of Rapid prototyping in the field of casting. After applying the inclusion criteria, we found 40 articles for reviewing. This study concluded that using Additive manufacturing in Investment casting in place of the conventional method is more cost- effective and time-efficient. Keywords: Additive Manufacturing, Rapid Investment Casting.
PREDICTION ANALYSIS OF DIVORCE RATE USING THE DECISION SUPPORT SYSTEM METHOD
Authors: Armonitha Shary , Rahmansyah Nugraha
Published: April 2022

The existence of divorce actually results in the separation of husband and wife bonds. This study aims to examine and examine the influence of divorce factors in the city of Padang. In this problem, the author predicts the divorce rate that will occur in the city of Padang in 2021 by reviewing divorce data in 2020. The method used in this study is normative juridical research by conducting observations, field notes, and interviews with related parties at the research location. . The results of this study will provide benefits for the Padang Class IA Religious Court to make a breakthrough that is able to reduce the divorce rate. The analysis in this problem also uses two methods of decision support systems, namely Single Moving Average (SMA) and Analytical Hierarchy Process (AHP). Based on manual calculations, the researcher can conclude that continuous disputes in the household can trigger divorce. Therefore, the Padang Class IA Religious Court can make a breakthrough in the form of education about the impact of divorce and education in solving a problem. The application of the Single Moving Average method can predict accurately for January 2021 as many as 96 cases for 5 period predictions with a MAPE of 11%. In the calculation of the Analytical Hierarchy Process method, the final calculation is 0.32 which shows that continuous disputes can lead to divorce.
EFFECT OF PBV, QR, NPM, DER, CR, TATTOO ON STOCK PRICES IN PROPERTY & REAL ESTATE COMPANIES
Authors: Wulandari Bayu , Sarah Sormin Debby , Ayuning Wigo Isti , Mia Sundari Sianturi Eunike
Published: April 2022

This study aims to determine the effect of price book value, quicki ratio, net profit ratio, debt to equity ratio, current ratio, and total asset turnover on stock prices. This research was conducted on service companies in the real estate sub-industry from 2018 to 2020. The object of research is 65 (sixty five) companies listed on the Indonesia Stock Exchange. The sampling technique used in this study was purposive sampling, and a total sample of 45 (forty five) companies was obtained. The data used is the financial statements of each sample company published on the website www.idx.co.id. The research method used is quantitative analysis method because the data are in the form of numerical data and empirical data. While the selected variables are in the form of units that can be calculated and measured. The results showed that partially the price book value, quick ratio, net profit margin, debt to equity ratio, current ratio, and total asset turnover had no significant effect on stock prices
INFLUENCE OF PROFITABILITY, ASSET STRUCTURE, SALES GROWTH AND BUSINESS RISK ON INVESTMENT
Authors: Dedi Dedi , Seyla Seyla , Lilia Wirda
Published: April 2022

This study aims to determine the effect of profitability, asset structure, sales growth and business risk on investment. In the food and beverage industry companies listed on the Indonesia Stock Exchange (IDX) in 2015-2019 the data used comes from the Indonesian stock exchange through the www.idx.co.id site and has been selected based on the criteria in this study. The population used in this study is companies engaged in the food and beverage industry, totaling 26 companies, using a purposive sample, the samples obtained are 14 companies. With this research, it becomes a science to help further researchers and also students or the general public who need information. From this research, it can be seen that profitability has a partial effect on the amount of investment. Asset structure, sales growth, and business risk are not partially affected and have no significant impact on investment in the food and beverage industry. But all variables affect simultaneously. The choice of this sector is due to the fact that currently Indonesia is the country with the 4th most populous population and is a consumption country. Of course, the need for food and beverages will always increase so that many companies are built on that basis, which made me interested in researching it.
Flow of time during energy measurements and the resulting time-energy uncertainty relations
Authors: Paiva Ismael L. , Lobo Augusto C. , Cohen Eliahu
Published: April 2022

Uncertainty relations play a crucial role in quantum mechanics. Well-defined methods exist for the derivation of such uncertainties for pairs of observables. Other approaches also allow the formulation of time-energy uncertainty relations, even though time is not an operator in standard quantum mechanics. However, in these cases, different approaches are associated with different meanings and interpretations for these relations. The one of interest here revolves around the idea of whether quantum mechanics inherently imposes a fundamental minimum duration for energy measurements with a certain precision. In our study, we investigate within the Page and Wootters timeless framework how energy measurements modify the relative "flow of time'' between internal and external clocks. This provides a unified framework for discussing the subject, allowing us to recover previous results and derive new ones. In particular, we show that the duration of an energy measurement carried out by an external system cannot be performed arbitrarily fast from the perspective of the internal clock. Moreover, we show that during any energy measurement the evolution given by the internal clock is non-unitary.
NUMERICAL ASSESSMENT OF CARRYING CAPACITY AND ANALYSIS OF PILOT BARETT BEHAVIOR IN GEOLOGICAL CONDITIONS OF VIETNAM
Authors: Mangushev Rashid , Nikitina Nadezhda , Чонг Ле Ван , Tereshchenko Ivan
Published: April 2022

The article provides an analysis and comparison of the bearing capacity of barrett piles in difficult geological conditions at a construction site in Hanoi - Vietnam based on the results of analytical calculations using various methods. In particular, it contains calculation results according to Building Code of Russian Federation SP 24.13330.2011 "Pile foundations" [1], by numerical modeling of the pile operation under load using the PLAXIS 3D and MIDAS GTS NX software package, based on the results of field tests with piles (static load method). It is noted that the bearing capacity of bored piles and barret piles, according to the results of full-scale static tests with a limiting settlement of 40 mm, is in good agreement with the numerical solution (with the adopted soil model Hardening Soil (HS)) and with the calculation by the analytical method according to the strength characteristics of the soil base
Rokok Dan Hipertensi
Authors: Rachmawati Faika , Puspita Tities , Suryatma Anton
Published: April 2022

Hypertension was one of the non-communicable diseases that may cause death in Indonesia. Through Healthy Indonesia Program with Family Approach (PIS-PK), the public health centers conduct home visits to collect family’s health status, such as risk factors and health outcomes involving smoking and hypertension. This study investigates the correlation of smoking and hypertension in two heath centers to the lowest and highest healthy family index (IKS) in Metro City, Lampung Province. The data analysis used multiple logistic regression. The results indicated Puskemas Mulyojati had 11.18% of people diagnosed with hypertension, while Puskesmas Iringmulyo had 5.14%. More smokers were higher in Mulyojati (27.30%) than those in Iringmulyo (23.38%). The proportion of smokers with hypertension in Mulyojati was 2.40% (OR 0.70; 95%CI 0.59-0.84; p 0.006) and in Iringmulyo was 1.09% (OR 0.87 95%CI 0.66-1.14; p 0.115). In Mulyojati, the odds of smokers contracting hypertension was 0.56 times lower than the non-smokers (95%CI 0.44-0.71; p <0,000); meanwhile, the smoking-hypertension relationship in Iringmulyo was not significant despite a bigger odds ratio (OR 0.83, 95%CI 0.59-1.17; p 0.293.) As a recommendation, both Puskesmas promote campaigns for a smoke-free movement, smoke-free areas and smoking cessation counseling to reduce the prevalence of hypertension.

Abstrak

Hipertensi merupakan salah satu penyakit tidak menular penyebab kematian di Indonesia. Melalui Program Indonesia Sehat dengan Pendekatan Keluarga (PIS-PK), puskesmas melakukan kunjungan rumah dan mengumpulkan data profil kesehatan keluarga, meliputi faktor risiko dan kejadian penyakit termasuk kebiasaan merokok dan hipertensi. Penelitian ini bertujuan mengetahui hubungan antara kebiasaan merokok dengan hipertensi di dua puskesmas yang memiliki Indeks Keluarga Sehat (IKS) terendah dan tertinggi di Kota Metro, Provinsi Lampung. Data dianalisis dengan regresi logistik berganda. Sebanyak 11,18% orang di Puskesmas Mulyojati didiagnosis hipertensi, sedangkan Puskesmas Iringmulyo sebesar 5,14%. Perokok lebih banyak ditemukan di Puskemas Mulyojati (27,30%) daripada di Puskesmas Iringmulyo (23,38%). Proporsi orang yang merokok dan didiagnosis hipertensi di Puskesmas Mulyojati sebanyak 2,40% (OR 0,70; IK 95% 0,59-0,84; p 0,000) sedangkan di Puskesmas Iringmulyo 1,09% (OR 0,87; IK 95% 0,66-1,14; p 0,325). Odd rasio orang merokok untuk mengidap hipertensi 0,56 kali dibandingkan dengan orang yang tidak merokok dengan hasil signifikan (IK 95% 0,44-0,71; p <0,000) di Puskesmas Mulyojati. Di Puskesmas Iringmulyo, meskipun odd rasionya sebesar 0,83, namun hasilnya tidak signifikan (IK 95% 0,59-1,17; p 0,293). Kedua Puskesmas disarankan untuk melakukan kampanye gerakan tanpa asap rokok, area bebas rokok dan konseling berhenti merokok untuk menurunkan prevalensi hipertensi.
Persepsi Mahasiswa UIN Walisongo Terhadap Covid-19 Dan Perilaku Kesehatan
Authors: Ramadhana Shela Delfia , Fadlilati Dian , Hidayatullah Ahmad Fauzan , Norra Bunga Ihda , Hariz Anif Rizqianti
Published: April 2022

Covid-19 is a disease caused by the coronavirus. Since the end of 2019, WHO has reported cases of pneumonia that occurred in Wuhan, Tiongkok, which then spread to several countries including Indonesia. The number of the spread of Covid-19 is increasing day by day, the government continues to try to break the chain of the spread of Covid-19. The success of efforts to break the Covid-19 chain depends on the public's knowledge and perception of Covid-19 and its prevention efforts. This study aims to determine the perceptions and behavior of UIN Walisongo students in preventing Covid-19. This study used a quantitative descriptive research method, with a data collection instrumen in the form of a questionnaire. Data collection techniques using a google form questionnaire with 10 statements and opinions from UIN Walisongo students. The study population was all students of UIN Walisongo Semarang and as a sample were 302 students from various faculties who were selected by nonprobability sampling. The results showed 86.49% of the students of UIN Walisongo have a "very good" perception of Covid-19. Healthy behaviors carried out by UIN Walisongo students as an effort to prevent Covid-19 include: washing hands, using masks, social distancing, taking vitamins and exercising. To increase the prevention of Covid-19, it is necessary to conduct health education directly or online through social media to communicate with the public.

Abstrak

Covid-19 merupakan penyakit yang disebabkan oleh virus corona. Pada akhir tahun 2019, WHO melaporkan kasus pneumonia yang terjadi di Wuhan, Tiongkok yang kemudian menyebar di beberapa negara termasuk Indonesia. Angka penyebaran Covid-19 semakin hari kian meningkat, pemerintah terus berupaya memutus rantai penyebaran Covid-19. Keberhasilan upaya pemutusan rantai Covid-19 tergantung dari pengetahuan dan persepsi masyarakat terhadap Covid-19 serta upaya pencegahannya. Penelitian ini bertujuan untuk mengetahui persepsi dan perilaku Mahasiswa UIN Walisongo dalam pencegahan Covid-19. Penelitian ini menggunakan metode penelitian deskriptif kuantitatif, dengan instrument pengumpulan data berupa kuesioner. Teknik pengumpulan data dengan menggunakan kuesioner google form dengan 10 pernyataan serta pendapat dari mahasiswa UIN Walisongo. Populasi penelitian adalah seluruh mahasiswa UIN Walisongo Semarang dan sebagai sampel adalah 302 mahasiswa dari berbagai fakultas yang dipilih dengan teknik nonprobability sampling. Hasil penelitian menunjukkan 86.49% mahasiswa UIN Walisongo mempunyai persepsi “sangat baik” terhadap Covid-19. Perilaku sehat yang dilakukan mahasiswa UIN Walisongo sebagai upaya pencegahan Covid-19 meliputi: cuci tangan, menggunakan masker, social distancing, mengonsumsi vitamin dan berolahraga. Untuk meningkatkan pencegahan Covid-19 perlu dilakukan penyuluhan kesehatan secara langsung atau online melalui media sosial untuk berkomunikasi dengan masyarakat.
Analisis Kualitatif Peran Ibu Terhadap Pencegahan COVID-19 Dan Pemberian Gizi Pada Masa Pandemi
Authors: Purnama Tri Bayu , Pasaribu Rahayu Sakinah , Siregar Kaaf Wajiah , Roszaliya Eka Githa
Published: April 2022

More than two million children suffer from malnutrition and more than 7 million children under the age of 5 suffer from stunted growth. Nutritional status is important as it is a risk factor for morbidity and mortality. The role of mothers is required to monitor the nutritional status of young children during the COVID-19 pandemic. This study aims to determine the role of mothers in monitoring the nutritional status of young children during the COVID-19 pandemic. In this study, a qualitative approach was used to describe maternal activities in monitoring infant nutritional status during the pandemic. Data collection was carried out through in-depth interviews using a questionnaire as an interview guide. The whistleblower research was conducted in Medan City with up to 4 people as an area with a high COVID-19 prevalence rate and with Sibolga City with up to 6 whistleblowers as a comparison city with a low COVID-19 prevalence in North Sumatra province. This study found that the whistleblowers still had not implemented the COVID-19 prevention protocol, e.g. B. by not cleaning items frequently touched with disinfectants because they did not have disinfectant, did not feel the need to be cleaned regularly and lacked knowledge. Most of the whistleblowers had given their young children balanced diets during the COVID-19 pandemic, but some of the whistleblowers found restrictions on eating vegetables and fruits.

Abstrak

Lebih dari dua juta anak menderita gizi buruk dan lebih dari 7 juta anak di bawah usia 5 tahun mengalami stunting. Status gizi penting karena merupakan salah satu faktor risiko terjadinya kesakitan dan kematian. Peran ibu dibutuhkan untuk memantau status gizi pada balita selama pandemi COVID-19. Penelitian ini bertujuan untuk mengetahui peran ibu terhadap pemantauan status gizi balita pada masa pandemi COVID-19. Pendekatan kualitatif digunakan pada penelitian ini untuk mendeskripsikan kegiatan yang dilakukan oleh ibu dalam pemantauan status gizi bayi pada masa pandemi. Pengumpulan data dilakukan dengan wawancara mendalam dengan menggunakan kuesioner sebagai panduan wawancara. Informan penelitian dilakukan pada Kota Medan sebanyak 4 orang sebagai daerah dengan tingkat penyebaran COVID-19 yang tinggi dan Kota Sibolga sebanyak 6 informan sebagai kota pembanding dengan penyebaran COVID-19 rendah di Provinsi Sumatera Utara. Penelitian ini menemukan bahwa informan masih belum menerapkan protokol pencegahan COVID-19 seperti tidak membersihkan barang-barang yang sering disentuh dengan disinfektan dikarenakan tidak punya disinfektan, tidak merasa perlu untuk dibersihkan secara berkala, dan kurangnya pengetahuan. Sebagian besar informan sudah memberi balita makanan gizi seimbang di masa pandemi COVID-19 tetapi ditemukan keterbatasan dalam konsumsi sayur dan buah pada beberapa informan.
Liouville type theorems to nonlinear fractional Laplacian system with different order
Authors: Wang Xinjing , Jia Zeya
Published: April 2022

In this paper, we prove Liouville type theorems for nonnegative solution
of nonlinear system which the fractional Laplacian different order. The
main method we use is the moving plane combined with integral
inequality.
Identification of chitin synthase activator in Aspergillus niger and its application in citric acid fermentation
Authors: Jiang Chunxu , Wang Han , Liu Menghan , Wang Li , Yang Ruwen , Wang Peng , Lu Zongmei , Zhou Yong , Zheng Zhiming , Zhao Genhai
Published: April 2022

Background: The biosynthesis of citric acid (CA) with Aspergillus niger
as a carrier is influenced by the morphology of the mycelium, which
depends on the morphogenesis-related genes. Methods: To study the effect
of chitin content on morphogenesis and fermentation performance, we used
RNA interference to knockdown chitin synthase C (chsC) and chitin
synthase activator (chs3) to obtaine the single-gene mutant strains A.
niger chs3 and chsC, as well as the double mutant A. niger chs3C.
Results: The CA fermentation performance of the two single mutants was
significantly higher than that of the double mutant. We determined
certein characteristics of CA high-yielding strain fermentation pellets;
the mutant A.niger chs3-4 exhibited greater CA production potential than
that of the WT strain in scale-up fermentation. In addition, when chsC
alone was silenced, there was very little change in chs3 mRNA levels,
whereas those of chsC were significantly reduced when just chs3 was
silenced. As this may be because of a synergistic effect between chsC
and chs3. Conclusion: This study is the first application of a
separation and combination strategy of chitin synthase and chitin
synthase activator and it provides new insights into the method for the
morphological study of A.niger fermentation and the interaction of
homologous genes.
Smarter symptom management for children with cancer: development and evaluation plans of a smartphone app to monitor patient-reported outcome measures (RESPONSE)
Authors: Bradford Natalie , Slater Penelope , Fielden Philippa , Douglas Matthew , Radford Claire , Carter Amanda , Condon Paula , Walker Rick , Badat Ashraf , Spencer Brooke , Edwards Rachel , Pitt Erin , Herbert Anthony
Published: April 2022

Background Symptoms and associated distress in children diagnosed and
treated for cancer are uniformly common, yet structured and systematic
symptom monitoring is not yet commonplace. With increasing pressures on
the healthcare workforce, improved systematic approaches to symptom
management are required. Methods Medical, nursing and allied health
oncology clinicians developed algorithms using consensus techniques to
ascertain thresholds of concern for each symptom for the Symptom
Screening in Pediatrics (SPPedi) tool, a Patient Reported Outcome
Measure (PROM). Algorithm vetting and refinement were achieved through
iterative interviews and consultation with clinicians. Self-management
evidence-based recommendations for each symptom were developed. The
algorithms were incorporated into an existing smartphone application
(MyQCH), as part of the Oncology Hub, and an iterative evaluation is
planned to test the feasibility, acceptability, safety, usefulness, and
other domains including a hybrid effectiveness trial
(ACTRN12621001084875). Discussion Digital solutions provide alternative
options for communication, information, and education and opportunities
to harness the best of community and hospital services. The Oncology Hub
and RESPONSE system is a comprehensive approach to symptom management
that includes a suite of tools and resources including a smartphone app
that collects PROMs and delivers symptom management advice, as well as
written resources for both the families of children with cancer and
clinicians. Conclusions Using technology offers new ways to think about
how clinicians and families communicate and share information.
Understanding how information is exchanged using technology, and how
this impacts clinical workflow is critical to successful implementation,
and to ultimately optimise symptom assessment management in children
with cancer.
A Lesser Scaup ( Aythya affinis ) Naturally Infected with Eurasian 2.3.4.4 Highly Pathogenic H5N1 Avian Influenza Virus – Movement Ecology and Host Factors
Authors: Sullivan Jeffery D. , Prosser Diann , Schley Hannah , Simmons Nathan , Homyack Josh , Weegman Matthew , Olsen Glenn , Berlin Alicia M. , Poulson Rebecca , Stallknecht David , Williams Christopher K.
Published: April 2022

Despite the recognized role of wild waterfowl in the potential dispersal
and transmission of highly pathogenic avian influenza (HPAI) virus,
little is known about how infection affects these birds. This lack of
information limits our ability to estimate viral spread in the event of
an HPAI outbreak, thereby limiting our abilities to estimate and
communicate risk. Here we present telemetry data from a wild Lesser
Scaup ( Aythya affinis), captured during a separate ecology study
in the Chesapeake Bay, Maryland. This bird tested positive for infection
with clade 2.3.4.4 HPAI virus of the A/goose/Guangdong/1/1996 (Gs/GD)
H5N1 lineage (results received post-release) during the 2021-22 ongoing
outbreaks in North America. While the infected bird was somewhat lighter
than other adult males surgically implanted with transmitters (790g,
=868g, n=11), it showed no clinical signs of infection at capture,
during surgery, nor upon release. The bird died 3d later, pathology
undetermined as the specimen was not able to be recovered. Analysis of
movement data within the 3d window showed that the infected individual’s
maximum and average hourly movements (3894.3m, 428.8m respectively) were
noticeably lower than noninfected conspecifics tagged and released the
same day (=21594.5m, =1097.9m, respectively; n=4). We identified four
instances where the infected bird had direct contact (fixes located
within 25m and 15 min) with another marked bird during this time.
Collectively, these data suggest that the HPAI positive bird observed in
this study may have been shedding virus for some period prior to death,
with opportunities for direct bird to bird or environmental
transmission. Although limited by low sample size and proximity to the
time of tagging, we hope that these data will provide useful information
as managers continue to respond to this ongoing outbreak event.
Stemflow metazoan transport from common urban tree species of varying canopy structure
Authors: Tonello Kelly Cristina , Lima Marcelle Teodoro , Urso-Guimarães Maria Virginia , Stan John Toland Van
Published: April 2022

The stemflow may wash canopy-dwelling metazoans to the litter and soils
below; however, metazoans transported by stemflow have been typically
ignored in past research. In fact, the visual presence of metazoans in
stemflow collection bins was reported as “contamination.” Thus, we
know little about these organisms’ transfer from plant canopies to the
surface. To investigate this topic, we monitored metazoan concentrations
and composition within stemflow that drained from 8 urban tree species
over 12 months. Metazoan concentration and composition in stemflow were
also analyzed with respect to tree canopy and bark traits to assess
whether, or to what extent, canopy metazoan dispersal was affected by
canopy structure. Tree structural traits studied here, include bark
texture, stem diameter at breast height (D) and canopy height-to-width
ratio (H:W). These traits were sorted into three classes: (1) furrowed-,
flaky/exfoliating- and smooth-bark texture; (2) <10, 10-20 and
>20cm D; and (3) <1, 1-2 and >2 H:W.
Analysis of 288 samples found 1,307 individuals distributed into 7
classes (16 orders), and one organism at phylum level. There were
considerable variations in metazoans’ density [ind L
] in stemflow, ranging from 1.0 to 16.9 ind.L
stemflow . Variability across individual trees was
high across species, but individual trees with the highest metazoan
stemflow density and flux were flaky-exfoliating-barked individuals in
the largest D size class with moderate-to-high canopy. On the other
hand, based on trait groups across all individuals, higher stemflow
metazoan density and flux was generally observed in smooth-bark trees in
largest D and H:W classes.
Successful monotherapy with autologous formalin-fixed tumor vaccine for a stage IV uterine cancer patient rejecting rational chemotherapy and immune-checkpoint-inhibitor treatment
Authors: Fukuda Katsuhiko , Ohno Tadao
Published: April 2022

A patient with stage IV uterine cancer displaying circulating tumor
cells and high microsatellite instability who had rejected standard
chemotherapy and immune-check-point inhibitor treatment received
monotherapy with autologous formalin-fixed tumor vaccine (AFTV). The
treatment resulted in shrinkage of multiple lung metastases, suggesting
that AFTV will be an attractive treatment option.
A novel machine learning method for diet quality evaluation by nutritional ingredients
Authors: jing ruixin , Liu Yu , Jiang Huaiyan , Wang Junfeng
Published: April 2022

The current mainstream dietary pattern analysis methods including
data-driven and investigator-driven methods have their own
limitations.Our goal is to develop a hybrid method to establish the
relationship between the intake of various nutrients and the quality of
the Chinese diet using machine learning methods. We employed the Chinese
Health Eating Index (CHEI) as a apriori expertise to evaluate the diet
quality of Chinese people and designed a scheme to predict the CHEI
score with nutritional ingredients using machine learning methods. Based
on the diet records of 28,000 respondents in the CHNS dataset, seven
machine learning regression models were evaluated, and the Gradient
Boosting model achieved the best R2 score (0.86). In addition, through
separate verification experiments, we found the performance of the
proposed method was stable among different population subgroups and the
predicted result was reliable.
The Impact of COVID-19 Pandemic on the Use of Emergency Medical Services System in Bangkok, Thailand
Authors: Sricharoen Pungkava , Huabbangyang Thongpitak , Trakulsrichai Satariya , Yuksen Chaiyaporn
Published: April 2022

Coronavirus disease 2019 (COVID-19) has widely affected the global
public health system, especially the emergency medical service (EMS),
which has been the first responders since 2020. However, this pandemic
persists with still limited studies on its impact on EMS. This study
aimed to compare the number of EMS patients and the operation periods of
Bangkok EMS in Thailand between 2020 (severe COVID-19 pandemic) and 2019
(prepandemic). Data of patients with severe COVID-19 were collected from
the emergency medical information system of Bangkok EMS center. Data
were compared between the two periods. A total of 178,594 patients were
serviced by EMS, with 93,288 during the study period and 85,306 during
the control period. The study period had more EMS patients overall by
9.36% (95% confidence interval [CI]: 9.16–9.55) and significantly
more EMS patients per day, with a mean difference of 21.19 (254.90 ±
25.55 vs. 233.71 ± 23.49; 95% CI: 17.63–24.76, p < 0.001),
than the control period. Furthermore, all EMS operation periods were
significantly longer during the study period. The COVID-19 pandemic
period had more patients managed by EMS and longer EMS operation periods
than the prepandemic period.