bluuebunny/crossref_metadata_2025 huggingface dataset:
Inflammatory Breast Cancer: The Cytokinome of Post-Mastectomy Wound Fluid Augments Proliferation, Invasion, and Stem Cell Markers
Authors: Tarek Alshaimaa , El-Sayed Shrouk Khalaf , Woodward Wendy A. , El-Shinawi Mohamed , Hirshon Jon Mark , Mohamed Mona Mostafa
Published: June 2022

Inflammatory breast cancer (IBC) is an aggressive phenotype with a high recurrence and low survival rate. Approximately 90% of local breast cancer recurrences occur adjacent to the same quadrant as the initial cancer, implying that tumor recurrence may be caused by residual cancer cells and/or quiescent cancer stem cells (CSCs) in the tumor. We hypothesized that wound fluid (WF) collected after modified radical mastectomy (MRM) may activate cancer cells and CSCs, promoting epithelial mesenchymal transition (EMT) and invasion. Therefore, we characterized the cytokinome of WF drained from post-MRM cavities of non-IBC and IBC patients. The WF of IBC patients showed a significantly higher expression of various cytokines than in non-IBC patients. In vitro cell culture models of non-IBC and IBC cell lines were grown in media conditioned with and/without WF for 48 h. Afterwards, we assessed cell viability, the expression of CSCs and EMT-specific genes, and tumor invasion. Genes associated with CSCs properties and EMT markers were regulated in cells seeded in media conditioned by WF. IBC-WF exhibited a greater potential for inducing IBC cell invasion than non-IBC cells. The present study demonstrates the role of the post-surgical tumor cavity in IBC recurrence and metastasis.
Remarkable Resilience of Forest Structure and Biodiversity Following Fire in the Peri-Urban Bushland of Sydney, Australia
Authors: Pendall Elise , Hewitt Alison , Boer Matthias M. , Carrillo Yolima , Glenn Nancy F. , Griebel Anne , Middleton Jason H. , Mumford Peter J. , Ridgeway Peter , Rymer Paul D. , Steenbeeke Greg L.
Published: June 2022

In rapidly urbanizing areas, natural vegetation becomes fragmented, making conservation planning challenging, particularly as climate change accelerates fire risk. We studied urban forest fragments in two threatened eucalypt-dominated (scribbly gum woodland, SGW, and ironbark forest, IF) communities across ~2000 ha near Sydney, Australia, to evaluate effects of fire frequency (0–4 in last 25 years) and time since fire (0.5 to >25 years) on canopy structure, habitat quality and biodiversity (e.g., species richness). Airborne lidar was used to assess canopy height and density, and ground-based surveys of 148 (400 m2) plots measured leaf area index (LAI), plant species composition and habitat metrics such as litter cover and hollow-bearing trees. LAI, canopy density, litter, and microbiotic soil crust increased with time since fire in both communities, while tree and mistletoe cover increased in IF. Unexpectedly, plant species richness increased with fire frequency, owing to increased shrub richness which offset decreased tree richness in both communities. These findings indicate biodiversity and canopy structure are generally resilient to a range of times since fire and fire frequencies across this study area. Nevertheless, reduced arboreal habitat quality and subtle shifts in community composition of resprouters and obligate seeders signal early concern for a scenario of increasing fire frequency under climate change. Ongoing assessment of fire responses is needed to ensure that biodiversity, canopy structure and ecosystem function are maintained in the remaining fragments of urban forests under future climate change which will likely drive hotter and more frequent fires.
Analysis of Ocean Parameters as Sources of Coastal Storm Damage: Regional Empirical Thresholds in Northern Spain
Authors: Rivas Victoria , Garmendia Carolina , Rasilla Domingo
Published: June 2022

This contribution aims to explore the role of oceanographic parameters on the damage caused by storms at the eastern Cantabrian coast (1996–2016). All wave storms affecting the study area were characterized in terms of several oceanographic parameters; among them, damaging storms (responsible for direct and tangible loss) were identified. Cross-referencing both databases makes it possible to find some thresholds that explain storm conditions associated with property damage. Particularly relevant are those responsible for significant and widespread damage: maximum significant offshore wave height >6.5 m, maximum total water level >6 m, SPI > 1700 m2h, and a storm duration >48 h. These values are exceptionally high, mostly exceeding the 95th percentile. A comparison has been made with other thresholds described in the literature. The concurrence of high wave height and high tidal level is crucial as the greatest damage is caused by the combination of wave impact and over-wash, so a long duration of the storm is necessary to coincide with high tide. An empirical Intensity-Duration threshold has also been obtained with the following function I = 248.7 D−0.45. Damage can occur with moderate storms, but with severe effects only with exceptional wave and sea-level values, during long-lasting storms.
Feasibility of Nonintubated Anesthesia for Lumboperitoneal Shunt Implantation
Authors: Huang Abel Po-Hao , Tsai Feng-Fang , Chen Chien-Chia , Lee Tzong-Shiun , Kuo Lu-Ting
Published: June 2022

Lumboperitoneal shunt (LPS) implantation is a cerebrospinal fluid diversion therapy for the communicating type of normal-pressure hydrocephalus (NPH); NPH mainly affects older adults. However, endotracheal intubation for mechanical ventilation with muscle relaxant increases perioperative and postoperative risks for this population. Based on knowledge from nonintubated thoracoscopic surgery, which has been widely performed in recent years, we describe a novel application of nonintubated anesthesia for LPS implantation in five patients. Anesthesia without muscle relaxants, with a laryngeal mask in one patient and a high-flow nasal cannula in four patients, was used to maintain spontaneous breathing during the surgery. The mean anesthesia time was 103.8 min, and the mean operative duration was 55.8 min. All patients recovered from anesthesia uneventfully. In our experience, nonintubated LPS surgery appears to be a promising and safe surgical technique for appropriately selected patients with NPH.
Effect of Negative Bias of HiPIMS and AIP Hybrid Deposition on Microstructure, Mechanical and Anti-Corrosive Properties of Cr2N/TiN Multilayer Coatings
Authors: Tu Rong , Yuan Yang , Yang Mai , Min Rui , Jiao Jiao , Li Qizhong , Yang Meijun , Ji Baifeng , Zhang Song
Published: June 2022

Multi-layered nitride coatings have been widely applied to improve the mechanical and anti-corrosive of metals and/or alloys. Cr2N/TiN multilayer coatings were prepared by the combination of high-power pulsed magnetron sputtering (HiPIMS) and arc ion plating (AIP). The Cr2N layer was co-deposited by HiPIMS and AIP, while the TiN layer was deposited by a single HiPIMS. With increasing the negative bias voltage (Vs) on substrate up to −100 V, the number and size of the droplets decreased; the average grain size of the coatings decreased from 9.4 to 7.5 nm and the hardness increased from 21.5 to 25.1 GPa, and the level of the adhesion of the coatings has reached HF1. The coatings obtained at Vs = −100 V present the best corrosion resistance in NaCl aqueous solution based on the anodic polarization curves and EIS spectroscopy.
Micropatterned Polypyrrole/Hydroxyapatite Composite Coatings Promoting Osteoinductive Activity by Electrical Stimulation
Authors: Xu Ji , He Yuan , Sun Yanan , Zhang Xiuming , Yi Yunfeng , Shi Wei , Ge Dongtao
Published: June 2022

Conductive polypyrrole (PPy) has excellent biocompatibility and structural stability. It is an ideal electroactive biomaterial that can apply exogenous electrical stimulation to promote osteoblast differentiation. However, PPy is a kind of bio-inert material, which does not have osteoinductive capacity. Therefore, we have introduced a kind of bioactive material, hydroxyapatite (HA), to construct PPy/HA composite to enhance bioactivity and osteoinduction. In addition, micron-topological morphology of scattered grid pattern has been designed and introduced to the PPy/HA coatings, which can further enhance the regulation ability of the coatings to the adhesion, proliferation and differentiation of MC3T3-E1 cells. In vitro simulated body fluids (SBFs) immersion test results have demonstrated that the fabricated micropatterned PPy/HA composite coatings perform bioactivity well and can promote the mineral deposition of HA on the surface. Moreover, it can also benefit the proliferation and osteognetic differentiation of MC3T3-E1 cells, when accompanied by external electrical stimulation (ES). In this study, we have successfully constructed electroactive and bioactive coatings, the method of which can potentially be applied to the surface functional modification of traditional bone repair metals.
Simulation of Epitaxial Film–Substrate Interaction Potential
Authors: Belim Sergey V. , Tikhomirov Ilya V. , Bychkov Igor V.
Published: June 2022

The formation of the substrate surface potential based on the Lennard-Jones two-particle potential is investigated in this paper. A simple atom’s square lattice on the substrate surface is considered. The periodic potential of the substrate atoms is decomposed into a Fourier series. The amplitude ratio for different frequencies has been examined numerically. The substrate potential is approximated with high accuracy by the Frenkel–Kontorova potential at most parameter values. There is a field of parameters in which the term plays a significant role, with a period half as long as the period of the substrate atoms. The ground state of the monoatomic film is modeled on the substrate potential. The film may be in both crystalline and amorphous phases. The transition to the amorphous phase is associated with a change in the landscape of the substrate potential. There are introduced order parameters for structural phase transition in the thin film. When changing the parameters of the substrate, the order parameter experiences a jump when changing the phase of the film.
Enhanced Metal Coating Adhesion by Surface Modification of 3D Printed PEKKs
Authors: Baek Inwoo , Lim Chul-Min , Park Kyoung Youl , Ryu Bong Ki
Published: June 2022

PEKK (polyether-ketone-ketone) polymer has been actively studied in applying electronic devices in satellites owing to its excellent light weight and thermal resistance. However, the limitation of metal coating to form on the PEKK surface is due to the high-volume resistivity and surface resistance. Here, we have investigated the correlations between the chemical treatment of the surface and adhesion strength between polymer–metal coating. Three-dimensional printed PEKK objects were manufactured and nickel was deposited on the surface by electroless plating. As the concentration of H2SO4 increased from 12.5 to 14.3 mol/L, the pore diameter showed a tendency to increase. However, as growing pore induced connecting each other, the pore size re-decreased from 15.1 to 18.0 mol/L. To control pore size and uniformity, we investigated the pore diameter of 3D printed PEKK as a function of treatment time and temperature. Uniform pores were observed at a temperature of 50 °C which were formed after 10 min and the average pore size was 0.28 μm. After H2SO4 swelling, samples were re-treated in the KMnO4-H3PO4 etching system for the hydrophilic group. KMnO4 broken C=C bonding and generated hydrophilic groups such as -COOH and -OH, the contact angle decreased from 64.7 to 51.1° compared with H2SO4 swelling. XPS survey spectra confirmed that not only breaking C=C bonding but also increasing hydrophilicity due to -OH, -C-, -SO3 and the catalyst absorption of Pd was improved. As a result of adhesive strength by ASTM D3359, compared with the H2SO4 swelling, the KMnO4-H3PO4 etching system showed 5B which is the best result in standard test methods by adhesive tape test and peeling amount on the tape was less than 0.01%.
Fluorinated-Triazole-Modified ZnO and Its Application in Marine Antifouling
Authors: Yang Yu , Wang Guoqing , Lei Longlin , Xiong Yangkai , Fang Zhiqiang , Huang Lei , Liu Jinbo , Hu Daxiong , Liao Jianhe
Published: June 2022

The accumulation of marine biological growth has irreversible negative effects on shipping and coastal fisheries. In this paper, a new antibacterial nanofiller—triazole fluoroaromatic hydrocarbon−modified nano−zinc oxide (ZnO−APTES−TRF)—was prepared by a Cu(I)−catalyzed azide–alkyne click chemical reaction. The modification of nano−ZnO with triazole ring fluoroaromatic hydrocarbons were testified by FT−IR, XPS, and EDS. The grafting rate of ZnO−APTES−TRF can reach 32.38%, which was verified by the TGA test. The ZnO−APTES−TRF was mixed with zinc acrylate resin to produce a low surface energy antifouling coating with a surface water contact angle of 106°. The bactericidal rate of ZnO−APTES−TRF against Escherichia coli, Staphylococcus aureus, and Pseudoalteromonas sp. can reach more than 98% due to the synergistic effect of triazole and fluorine. The 120−day marine experiment shows that the low surface energy antifouling coating of ZnO−APTES−TRF/ZA is expected to be widely used in the field of marine antifouling.
Color Variability Constrains Detection of Geometrically Perfect Mirror Symmetry
Authors: Dresp-Langley Birgitta
Published: June 2022

Symmetry in nature is a result of biological self-organization, driven by evolutionary processes. Detected by the visual systems of various species, from invertebrates to primates, symmetry determines survival relevant choice behaviors and supports adaptive function by reducing stimulus uncertainty. Symmetry also provides a major structural key to bio-inspired artificial vision and shape or movement simulations. In this psychophysical study, local variations in color covering the whole spectrum of visible wavelengths are compared to local variations in luminance contrast across an axis of geometrically perfect vertical mirror symmetry. The chromatic variations are found to delay response time to shape symmetry to a significantly larger extent than achromatic variations. This effect depends on the degree of variability, i.e., stimulus complexity. In both cases, we observe linear increase in response time as a function of local color variations across the vertical axis of symmetry. These results are directly explained by the difference in computational complexity between the two major (magnocellular vs. parvocellular) visual pathways involved in filtering the contrast (luminance vs. luminance and color) of the shapes. It is concluded that color variability across an axis of symmetry proves detrimental to the rapid detection of symmetry, and, presumably, other structural shape regularities. The results have implications for vision-inspired artificial intelligence and robotics exploiting functional principles of human vision for gesture and movement detection, or geometric shape simulation for recognition systems, where symmetry is often a critical property.
Long-Term Tillage and Irrigation Management Practices: Impact on Carbon Budgeting and Energy Dynamics under Rice–Wheat Rotation of Indian Mid-Himalayan Region
Authors: Choudhary Mahipal , Panday Suresh C. , Meena Vijay S. , Yadav Ram P. , Singh Sher , Parihar Manoj , Mishra Pankaj K. , Bisht Jaideep K. , Pattanayak Arunava
Published: June 2022

In modern agriculture, reducing the carbon footprint and emission of greenhouse gases with greater energy efficiency are major issues for achieving the sustainability of agricultural production systems. To address this issue, a long-term field experiment was established from 2001 through 2016 with two contrasting tillage practices (ZT: zero tillage; CT: conventional tillage) and four irrigation schedules {I-1: pre-sowing (PS), I-2: PS + crown root initiation (CRI), I-3: PS + CRI + panicle initiation (PI)/flowering (FL), and I-4: PS + CRI + PI/FL + grain filling (GF)}. The grain yield of rice, wheat and the rice–wheat system was increased significantly by 23.6, 39.5 and 32.8%, respectively, with irrigation at four stages (I-4) compared to a single stage (I-1). Energy appraisal results exhibited that 17.2% higher energy was consumed under CT as compared to ZT (25,894 MJ ha−1). Fertilizer application consumed the highest energy (46.5–54.5%), followed by irrigation (8.83–19.5%), and the lowest energy consumption was associated with winnowing, packing and transport (2.07–2.43%) operations. The total energy output of the rice–wheat system did not change significantly among contrast tillage, but higher energy was obtained under CT (214,603 MJ ha−1) as compared to ZT (209,728 MJ ha−1). ZT practice improved the energy use efficiency (EUE), energy productivity (Ep) and energy profitability (Eprof) by 16.6, 21.0 and 16.6%, respectively, over CT. The EUE, SE (specific energy), Ep, net energy return (NER) and Eprof were enhanced by 17.1, 16.6, 21.0, 36.5 and 20.6%, respectively, with irrigation at four stages (I-4) compared to a single stage (I-1). Zero tillage plots reflected a 8.24% higher carbon use efficiency (CUE) and a 9.0% lower carbon footprint than CT plots. Among irrigation schedules, application of I-4 showed a 8.13% higher CUE and a 9.0% lower carbon footprint over single irrigation (I-1). This investigation indicated that ZT with irrigation at four stages (I-4) was the most sustainable option for improving the EUE and CUE with minimal GHGs emissions from the rice–wheat cropping system of Indian mid-Himalayan regions.
Evolution of Structure and Properties of Micro-Nano Structure 2507 Duplex Stainless Steel Prepared by Aluminothermic Reduction
Authors: Zhan Faqi , Liu Xiao , Zhang Hua , Wang Keliang , Xu Shipeng , Zhu Min , Zheng Yuehong , La Peiqing
Published: June 2022

In this work, a large ingot of micro-nano structure 2507 duplex stainless steel was prepared in a single step using the aluminothermic reaction method. Chromium having different excess fractions were added to reaction powders to make up for evaporation loss, and the results show that the composition and structure of 2507 duplex stainless steel with a chromium excess ratio of 70% are satisfactory. The volume fraction of nanocrystalline in as-cast alloy was 41% and the average grain size was 34 nm. Additionally, the anticipated steels were rolled roughly with deformation of 40% at 1000 °C and followed by fine rolling with deformation of 30, 50 and 70%, separately, at 800 °C. Then, the effects of rolling deformation and precipitation on mechanical properties were studied in detail. Compared with the as-cast alloy, there was no phase transformation in the alloys with deformation of 30 and 50%, and they were still composed of γ and α phases, whereas the σ phase appeared in the alloy with deformation of 70%. When the deformation was 50%, the rolled alloy achieved the best performance, and the tensile strength, yield strength, and elongation were 912 MPa, 523 MPa, and 24.3%, respectively.
TiN–Fe Vertically Aligned Nanocomposites Integrated on Silicon as a Multifunctional Platform toward Device Applications
Authors: Kalaswad Matias , Zhang Di , Rutherford Bethany X. , Lu Juanjuan , Barnard James P. , He Zihao , Liu Juncheng , Wang Haohan , Xu Xiaoshan , Wang Haiyan
Published: June 2022

Transition metal nitrides such as titanium nitride (TiN) possess exceptional mechanical-, chemical-, and thermal-stability and have been utilized in a wide variety of applications ranging from super-hard, corrosion-resistive, and decorative coatings to nanoscale diffusion barriers in semiconductor devices. Despite the ongoing interest in these robust materials, there have been limited reports focused on engineering high-aspect ratio TiN-based nanocomposites with anisotropic magnetic and optical properties. To this end, we explored TiN–Fe thin films with self-assembled vertical structures integrated on Si substrates. We showed that the key physical properties of the individual components (e.g., ferromagnetism from Fe) are preserved, that vertical nanostructures promote anisotropic behavior, and interactions between TiN and Fe enable a special magneto-optical response. This TiN–Fe nanocomposite system presents a new group of complex multifunctional hybrid materials that can be integrated on Si for future Si-based memory, optical, and biocompatible devices.
Effects of Basicity and Al2O3 Content on Viscosity and Crystallization Behavior of Super-High-Alumina Slag
Authors: Wang Shuai , Jiang Ying , Guo Yufeng , Yang Zhuang , Chen Feng , Yang Lingzhi , Li Guang
Published: June 2022

The CaO-SiO2-MgO-Al2O3 slags with high alumina content are widely applied in various pyrometallurgical processes. However, for super-high-alumina slags, especially for those with alumina content of more than 25 wt%, there is a lack of relevant studies about the properties of slag. The melting behavior, viscosity, structural property, and crystallization behavior of high-alumina slag with the fixed MgO content of 11.13 wt% and Al2O3 content from 27.61 wt% to 40 wt% were investigated. The results revealed that the liquidus temperatures and complete solidification temperatures of slag increased with the increasing binary basicity and Al2O3 content. The melting temperature and viscosity of the CaO-SiO2-11.13wt%MgO-Al2O3 slag system increased with the increasing basicity from 0.8 to 1 and Al2O3 content from 27.61 wt% to 40 wt%. The increase in Al2O3 caused the formation of high-crystallinity and high melting point materials in the slag, such as spinel and Åkermanite. A large number of non-uniform phases could quickly crystallize out of the solids present in the slag melt, thereby increasing the slag viscosity and deteriorating the fluidity of the slag.
Crystallization Kinetics of the Fe68Nb6B23Mo3 Glassy Ribbons Studied by Differential Scanning Calorimetry
Authors: Liu Yongqin , Zhu Man , Du Yuanyuan , Yao Lijuan , Jian Zengyun
Published: June 2022

Fe-based metallic glass has wide industrial application due to its unique mechanical behavior and magnetic properties. In the present work, the non-isothermal crystallization kinetics in Fe68Nb6B23Mo3 glassy alloys were investigated by differential scanning calorimeter (DSC). The results indicate that both the glass transformation and crystallization process display an obvious kinetic effect. The activation energy is calculated using Kissinger’s method and Ozawar’s method. The activation energy for Tg (glass transition temperatures), Tx (crystallization initiation temperatures) and Tp (crystallization peak temperatures) calculated from Kissinger equation, is 308 ± 4, 342 ± 5 and 310 ± 7 kJ mol−1, respectively. The activation energy for Tg, Tx and Tp calculated from Ozawa equation is 322 ± 3, 356 ± 5 and 325 ± 7 kJ mol−1, respectively. With the increase of the crystallization volume fraction x, the Avrami exponent n(x) first decreases and then increases. At the preliminary step, 0 < x < 0.25, 2.5 < n(x) < 4.0 stands for the growth from a small size with an increasing nucleation rate. When 0.25 < x < 0.71, n(x) decreases from 2.5 to 1.5, indicating that this stage is controlled by the growth of small particles with a decreasing nucleation rate.
Stoichiometric Growth of Monolayer FeSe Superconducting Films Using a Selenium Cracking Source
Authors: Zhu Kejing , Wang Heng , Zhu Yuying , Zang Yunyi , Feng Yang , Tong Bingbing , Zhao Dapeng , Xie Xiangnan , Chang Kai , He Ke , Liu Chong
Published: June 2022

As a novel interfacial high-temperature superconductor, monolayer FeSe on SrTiO3 has been intensely studied in the past decade. The high selenium flux involved in the traditional growth method complicates the film’s composition and entails more sample processing to realize the superconductivity. Here we use a Se cracking source for the molecular beam epitaxy growth of FeSe films to boost the reactivity of the Se flux. Reflection high-energy electron diffraction shows that the growth rate of FeSe increases with the increasing Se flux when the Fe flux is fixed, indicating that the Se over-flux induces Fe vacancies. Through careful tuning, we find that the proper Se/Fe flux ratio with Se cracked that is required for growing stoichiometric FeSe is close to 1, much lower than that with the uncracked Se flux. Furthermore, the FeSe film produced by the optimized conditions shows high-temperature superconductivity in the transport measurements without any post-growth treatment. Our work reinforces the importance of stoichiometry for superconductivity and establishes a simpler and more efficient approach to fabricating monolayer FeSe superconducting films.
A Pan-Canadian Consensus Statement on First-Line PARP Inhibitor Maintenance for Advanced, High-Grade Serous and Endometrioid Tubal, Ovarian, and Primary Peritoneal Cancers
Authors: Tinker Anna V. , Altman Alon D. , Bernardini Marcus Q. , Ghatage Prafull , Gien Lilian T. , Provencher Diane , Salvador Shannon , Doucette Sarah , Oza Amit M.
Published: June 2022

The majority of patients with advanced, high-grade epithelial-tubo ovarian cancer (EOC) respond well to initial treatment with platinum-based chemotherapy; however, up to 80% of patients will experience a recurrence. Poly(ADP-ribose) Polymerase (PARP) inhibitors have been established as a standard of care maintenance therapy to prolong remission and prevent relapse following a response to first-line platinum-chemotherapy. Olaparib and niraparib are the PARP inhibitors currently approved for use in the first-line maintenance setting in Canada. Selection of maintenance therapy requires consideration of patient and tumour factors, presence of germline and somatic mutations, expected drug toxicity profile, and treatment access. This paper discusses the current clinical evidence for first-line PARP inhibitor maintenance therapy in patients with advanced, high-grade EOC and presents consensus statements and a treatment algorithm to aid Canadian oncologists on the selection and use of PARP inhibitors within the Canadian EOC treatment landscape.
Effects of Sediment Types on the Distribution and Diversity of Plant Communities in the Poyang Lake Wetlands
Authors: Li Jie , Liu Yizhen , Liu Ying , Guo Huicai , Chen Gang , Fu Zhuoting , Fu Yvying , Ge Gang
Published: June 2022

At small scales, sedimentary deposition types mediate hydrological changes to drive wetland vegetation distribution patterns and species diversity. To examine the effects of sediment types on the distribution and diversity of plant communities in a wetland region, 150 quadrats were investigated (elevation range of 10.5–12.5 m) in the lake basin areas of Poyang Lake. We divided the surface soil into three sediment types (lacustrine sediments, fluvio-lacustrine sediments, and fluvial sediments), and then compared and analyzed the distribution and species diversity of the wetland plants among them. The results revealed the following findings: (i) within this elevation range, Carex cinerascens, Carex cinerascens–Polygonum criopolitanum, Polygonum criopolitanum, and Phalaris arundinacea communities exist; (ii) from lacustrine sediments to fluvial sediments, the distribution of plant communities showed a transition trend—with the Carex cinerascens and Phalaris arundinacea communities shifting into the Polygonum criopolitanum community; (iii) detrended correspondence analysis and redundancy analysis demonstrated that the soil particle composition and flood duration in 2017 generated a differential wetland plant distribution under the conditions of three sediment types along the littoral zones of Poyang Lake; and (iv) the plant communities on the lacustrine sediments had a higher species diversity than those established on the fluvio-lacustrine sediments and fluvial sediments.
Distribution, Biogeography and Characteristics of the Threatened and Data-Deficient Flora in the Southwest Australian Floristic Region
Authors: Gosper Carl R. , Percy-Bower Julia M. , Byrne Margaret , Llorens Tanya M. , Yates Colin J.
Published: June 2022

The Southwest Australian Floristic Region (SWAFR) supports an exceptional number of threatened and data-deficient flora. In this study, we: (i) collated statistics on the number, listing criteria and tenure of occurrence of threatened and data-deficient flora; (ii) conducted spatial and biogeographic analyses to address questions concerning patterns of diversity of threatened and data-deficient flora relative to the whole flora and evolutionary and threat drivers; and (iii) examined whether threatened and data-deficient flora richness is evenly distributed across plant lineages. We found that although threatened and data-deficient flora occurred across the breadth of the SWAFR, high richness was concentrated in a limited number of locations, which were not always strongly aligned with areas of higher land transformation. Data-deficient flora demonstrated different spatial patterns of occurrence to threatened flora. Approximately 70% of the populations of threatened and data-deficient flora occurred outside of lands managed primarily for conservation. Both evolutionary history and contemporary threats contribute to the current status and distribution of diversity of the threatened and data-deficient flora, with evolutionary history playing a significant role in predisposing a portion of the flora to having population traits that result in those flora meeting IUCN Red List criteria, along with ecological traits that predispose some to specific novel threats. An understanding of the distribution of species and threats, flora traits, and how these traits mediate susceptibility to threats, offers one potential way forward for an initial assessment of which of the 1819 data-deficient flora may be most at risk of extinction.
Eight New Records of Siphonophores (Cnidaria: Hydrozoa) in Korean Waters
Authors: Park Nayeon , Lee Wonchoel
Published: June 2022

Taxonomical research on siphonophores is lacking despite their high biodiversity. We collected siphonophores in Jeju and the southern coasts of Korea and conducted morphological redescriptions using multi-focus stacked digital images. As a result, we revealed eight unrecorded siphonophores (Abyla haeckeli, Ceratocymba leuckartii, Bassia bassensis, Dimophyes arctica, Lensia subtilis, Lensia subtiloides, Muggiaea atlantica, and Nanomia bijuga). Six genera, excluding Muggiaea, were reported for the first time in Korean waters, and subfamily Abylinae, to which Abyla haeckeli and Ceratocymba leuckartii belong, was also first recorded in Korea. The distributions and habitats of these species were summarized, with most of the species having cosmopolitan distributions but variations in individual size depending on environmental conditions. Phylogenetic analysis based on mtCOI was conducted for each family. Finally, we updated the species list of siphonophores in Korean waters to include 3 suborders, 5 families, 3 subfamilies, 14 genera, and 21 species. Our findings constitute baseline data for further research on Korean siphonophores.
DNA Barcoding of the Market Samples of Single-Drug Herbal Powders Reveals Adulteration with Taxonomically Unrelated Plant Species
Authors: Balaji Raju , Parani Madasamy
Published: June 2022

Herbal drugs are increasingly becoming a viable alternative to allopathic medicine. Since powdered herbal drugs are more prone to adulteration than intact plant parts, their authentication becomes essential to ensure the safety and efficacy of herbal drugs. This study authenticated 107 single-drug herbal powders, representing 65 species from 60 genera and 35 families, collected from the markets in Tamil Nadu, India. DNA barcoding using the rbcL marker revealed that 58 samples (54%) were authentic, and 49 (46%) were adulterant. About 41% of the adulterant samples were a mixture of more than one species, possibly due to unintentional cross-contamination during processing. In 59% of the adulterant samples, the authentic species was entirely substituted with taxonomically and medicinally unrelated species, 72% of which belonged to different orders and families, while 28% were from other genera. Despite the taxonomic diversity, 20% of adulterant spe, cies had a morphological resemblance to the authentic species. It is not known whether their use as adulterants is intentional. In a detailed study on DNA barcoding of 17 powder samples from Ocimum tenuiflorum, 88% of the samples were authentic. These results indicate that the extent of adulteration is not high in all the species. Approximately, 95% of the samples collected for this study were produced by companies with limited resources and expertise in the unorganized sector. Hence, training them on species identification and providing simple and cost-effective authentication tools will likely reduce adulteration in the market samples.
Dramatic Declines of Evening Grosbeak Numbers at a Spring Migration Stop-Over Site
Authors: Robinson W. Douglas , Greer Jessica , Masseloux Juliana , Hallman Tyler A. , Curtis Jenna R.
Published: June 2022

Evening Grosbeak (Coccothraustes vespertinus) populations have been hypothesized to be in steep decline across North America. Data characterizing long-term changes are needed to quantify the magnitude of the declines. We surveyed grosbeaks at a spring migratory stop-over site in Corvallis, Oregon, USA, where birds gather annually during April and May to feast on elm (Ulmus spp.) seeds before departing to breeding sites. An estimate produced by a statistics professor in the 1970s indicated peak numbers were 150,000 to 250,000 birds. Our surveys in 2013–2015 found annually variable numbers, from a few hundred grosbeaks in the lowest year to less than five thousand birds in the highest year. If the original estimate is approximately true, Evening Grosbeak numbers have experienced dramatic declines, averaging −2.6%/year, over the last four decades. Our local observation of declines during spring aligns with declines documented in winter across North America by bird feeder studies and in summer by the Breeding Bird Survey. We explore potential explanations for the changes in population size, such as influences of spruce budworm outbreaks, disease, and decreased structural diversity of forests owing to harvest practices. We also consider the challenges of interpreting changes in abundance of species with exceptionally variable populations, especially if population fluctuations or cycles may have long periodicities. Finally, we call for additional planned surveys to track the numbers of this enigmatic and charismatic species.
Performance Evaluation of the VITEK2 and Sensititre Systems to Determine Colistin Resistance and MIC for Acinetobacter baumannii
Authors: Chung Hae-Sun , Kim Soo-Kyung , Hahm Chorong , Lee Miae
Published: June 2022

Performances of the colistin antimicrobial susceptibility testing (AST) systems of Acinetobacter baumannii vary depending on the manufacturer, and data on colistin-resistant A. baumannii are limited. We evaluated the VITEK2 and Sensititre systems to determine colistin resistance and minimum inhibitory concentration (MIC) for A. baumannii isolated from a clinical microbiology laboratory. A total of 213 clinical A. baumannii isolates were tested, including 81 colistin-resistant A. baumannii. ASTs were performed using the VITEK2 and Sensititre systems according to the manufacturer’s instructions. Reference MICs for colistin were determined using the manual broth microdilution method (BMD). The results of the two AST methods were compared with the BMD results. VITEK2 and Sensititre systems showed category agreements of 95.3% and 99.1%, respectively. VITEK2 had a relatively high very major error (VME) rate (9.9%). Sensititre reported higher MICs than the reference method for the susceptible isolates and showed low essential agreement. In conclusion, the automated systems investigated in this study showed good category agreements for colistin AST of A. baumannii. However, VITEK2 had a high VME rate, and Sensititre had differences in MIC results. Colistin AST remains a challenging task in the clinical laboratory.
Anti-Occlusion UAV Tracking Algorithm with a Low-Altitude Complex Background by Integrating Attention Mechanism
Authors: Wang Chuanyun , Shi Zhongrui , Meng Linlin , Wang Jingjing , Wang Tian , Gao Qian , Wang Ershen
Published: June 2022

In recent years, the increasing number of unmanned aerial vehicles (UAVs) in the low-altitude airspace have not only brought convenience to people’s work and life, but also great threats and challenges. In the process of UAV detection and tracking, there are common problems such as target deformation, target occlusion, and targets being submerged by complex background clutter. This paper proposes an anti-occlusion UAV tracking algorithm for low-altitude complex backgrounds by integrating an attention mechanism that mainly solves the problems of complex backgrounds and occlusion when tracking UAVs. First, extracted features are enhanced by using the SeNet attention mechanism. Second, the occlusion-sensing module is used to judge whether the target is occluded. If the target is not occluded, tracking continues. Otherwise, the LSTM trajectory prediction network is used to predict the UAV position of subsequent frames by using the UAV flight trajectory before occlusion. This study was verified on the OTB-100, GOT-10k and integrated UAV datasets. The accuracy and success rate of integrated UAV datasets were 79% and 50.5% respectively, which were 10.6% and 4.9% higher than those of the SiamCAM algorithm. Experimental results show that the algorithm could robustly track a small UAV in a low-altitude complex background.
Sectoral Transformation of the Economic System during Crisis and Stable Growth Periods (A Case Study of the European Countries)
Authors: Vasin Sergey Mikhailovich
Published: June 2022

Sectoral structures are one of the critical and dynamic components of any social system subjected to either external or internal factors. The purpose of the paper is to reveal and validate characteristic features of transformation regarding economic sectoral structures during the crisis of the socio-economic system and the period of its coordinated development in order to determine the most stable industry sectors. This paper reveals the specificity of sectoral transformations in European countries during the crisis of 2008–2009 and the stable growth of 2010–2019. The analysis is premised on Robert B. Reich’s sectoral structure, comprising production, in-person, intellectual, and communication services sectors. To conduct the research, statistical data analysis using the Gatev coefficient, and correlation and comparative analysis are applied. It is concluded that the mutable nature of sectoral dynamics depends on the planned changes resulting either from business expectations and interests, or state intervention. Yet, transformation is likely due to external and internal shocks (economic upheavals and wars), and unexpected events (natural disasters, epidemics, and pandemics). Over the last 15 years, the sectoral structure has been subjected to most of the above collisions. In-person, intellectual, and communication services sectors are least affected during the economic crisis. In the European countries, the period of economic growth is characterized by the growing dominance of intellectual and communication services sectors. There is a trend of decreasing the share of mining and quarrying in the sectoral production structure in favor of manufacturing industries and services.
SAGA-Supporting Social-Emotional Development in Early Childhood Education: The Development of a Mentalizing-Based Intervention
Authors: Kalland Mirjam , Linnavalli Tanja , von Koskull Malin
Published: June 2022

The aim of the SAGA project is to support children’s social-emotional development and teacher mentalizing by promoting regular shared story-book reading with mentalizing dialogs in early childhood education and care (ECEC) centers. The theoretical phase, the modeling phase (Phase I), and the exploratory phase (Phase II) of the SAGA intervention, as well as the research protocol for the final trial (Phase III), are described in the present article.
Comparing the Two Educational Systems for Visually Impaired Students in Sudan: Pros and Cons
Authors: Salih Hisham E. Bilal , Kakizawa Toshibumi
Published: June 2022

Students with visual impairment in Sudan are usually accepted into residential segregated schools during their pre-high school years. This schooling system remains a subject of excessive debate among those interested in this field of study. This debate is part of an ongoing conversation and discussion on the merits and demerits of integrating disabled children with non-disabled peers at regular schools. This study aimed to answer three main questions pertaining to this subject. The first one tackles whether the placement of visually impaired students in specialized schools for the blind in Sudan (henceforth specialized schools) serves their education best. The second compares the advantages and disadvantages of integrating this group of students into regular schools as opposed to separating them into specialized schools. The third question is concerned with the competencies which the teachers at the Sudanese General Basic School should have in order to fulfill the requirements of the inclusive education setting. Interviews were conducted with a group of 20 participants; 10 of these were students who joined schools for the blind and regular schools in Sudan, while the remaining participants were teachers and personnel in the field of education for the visually impaired in Sudan. Thematic analysis was used to analyze the interview data, which revealed that students with visual impairment, teachers who work in specialized schools, and the group of special education officials who participated in this study were in favor of inclusive education at regular schools after securing the necessary educational needs for these students to access school curricula equal to their sighted peers. Many practical solutions and suggestions have been presented to enhance the education of the visually impaired in Sudan.
Using Interactive Online Pedagogical Approaches to Promote Student Engagement
Authors: Muir Tracey , Wang Isabel , Trimble Allison , Mainsbridge Casey , Douglas Tracy
Published: June 2022

The COVID-19 outbreak in late 2019 required a complete shift to online learning across all educational institutions, including universities. The rapid transition to online learning globally meant that many educators were suddenly tasked with adapting their classroom-based pedagogy to the online space. While this was undoubtedly challenging for teachers and students, it also opened up possibilities for reimagining the delivery of content, along with creating increased access for students who had barriers for studying remotely before the impact of COVID-19. The study discussed in this paper examines the experiences of students studying at a regional Australian university that already offered online courses, and whose instructors were already using a diverse range of online delivery tools. Specifically, the study sought to investigate how instructors used interactive strategies to promote student engagement, and how the interaction between learner and content influences student engagement. With research showing that online students typically have higher attrition rates than their on-campus counterparts, engagement has been identified as an important factor in online learning. Online interaction in particular is considered to be instrumental in influencing student engagement and positively impacting student satisfaction, persistence, and academic performance. Data collected from interviews conducted with two different cohorts of students, studying two different courses (mathematics education and Chinese language) at the same university, demonstrated ways instructors utilised interactive online pedagogies to engage students with potentially challenging course content. The study has implications for online educators who are looking for ways to adapt their on-campus courses to online delivery, with a focus on engaging and maintaining online students’ interest and ongoing participation in their courses.
Improving Symbolic System-Level Synthesis by Solver Coordination and Domain-Specific Heuristics
Authors: Haubelt Christian , Rausch Alexander
Published: June 2022

Deciding binding, routing, and scheduling within system synthesis for hard real-time systems can be a challenging task. Symbolic methods leveraging results from the area of satisfiability modulo theories (SMT) solving have shown to be scalable methods for this by splitting the work between a logic solver for routing and binding, and a background theory solver performing schedulability analysis. For these methods, in order to prune the search space of infeasible implementations efficiently, a feedback by the background theory is required. It can be observed that previous approaches might fail here as feedback cannot be derived within a reasonable amount of time. We propose a coordinated synthesis approach that overcomes this issue. Here, we leverage an answer set solver as logic solver that is enhanced with a scheduling-aware binding and routing refinement. Based on the answer set solver’s decisions for binding and routing, a background theory solver then computes time-triggered schedules to resolve resource access conflicts. If no feasible schedule exists, a feedback to the answer set solver can be derived within reasonable time. Our experiments synthesizing massively parallel hardware architectures show that our approach increases the applicability of symbolic synthesis considerably. While more than half of the investigated instances in our experiments cannot be solved in the non-coordinated approach already at small 2-dimensional 3×3 tiled mesh hardware architectures with 60% average computational utilization per tile, the coordinated synthesis approach scales up to 5×5 architectures with average utilization of 70% per tile (2.8× the hardware architecture size than before). Furthermore, we increase the scalability and the robustness of our approach by encoding our domain-knowledge within domain-specific heuristics in our designated answer set solver. Within our experiments, we observe that the domain-specific heuristics enable us to scale up to 6×6 architectures with 70% average utilization per tile.
Accurate ECG Classification Based on Spiking Neural Network and Attentional Mechanism for Real-Time Implementation on Personal Portable Devices
Authors: Xing Yuxuan , Zhang Lei , Hou Zhixian , Li Xiaoran , Shi Yueting , Yuan Yiyang , Zhang Feng , Liang Sen , Li Zhenzhong , Yan Liang
Published: June 2022

Electrocardiogram (ECG) heartbeat classification plays a vital role in early diagnosis and effective treatment, which provide opportunities for earlier prevention and intervention. In an effort to continuously monitor and detect abnormalities in patients’ ECG signals on portable devices, this paper present a lightweight ECG heartbeat classification method based on a spiking neural network (SNN), a relatively shallow SNN model integrated with a channel-wise attentional module. We further explore the best-optimized architecture, which benefits from leveraging the full advantages of the SNN potential with the attention mechanism to process the classification task at low power and capture prominent features concerning the time, morphology, and multi-channel representations of the ECG signal. Results show that our model achieves overall classification accuracy of 98.26%, sensitivity of 94.75%, and F1 score of 89.09% on the MIT-BIH database, with energy consumption of 346.33 μJ per beat and runtime of 1.37 ms. Moreover, we have conducted multiple experiments to compare against current state-of-the-art methods using their assessment strategies to evaluate our model implementation on FPGA. So far, our work achieves comparable overall performance with all the literature in terms of classification accuracy, energy consumption, and real-time capability.