bluuebunny/crossref_metadata_2025 huggingface dataset:
Syarat Cukup Ketaksamaan Hӧlder dan Ketaksamaan Minkowski di Perumuman Ruang Morrey
Authors: Ummah Nahdliyatul , Rahman Hairur , Ismiarti Dewi
Published: February 2022

The purpose of this research is to show the sufficient condition for Hӧlder inequality and Minkowski inequality in generalization of Morrey space and its weak space, namely generalization of weak Morrey space. This research focuses on the application of Hӧlder inequality and Minkowski inequality in generalization of Morrey space and generalization of weak Morrey space based on the characteristics of the two spaces in the set of n-dimensional real numbers.
Escuela técnica y trabajo en Argentina
Authors: Fernández Natalia Noemí
Published: February 2022

La escuela secundaria técnica cumple un papel fundamental en la formación de la fuerza de trabajo en Argentina, con lo cual, existe una compleja articulación entre educación secundaria técnica y trabajo. En este trabajo ponemos en diálogo la dimensión de la normativa educativa con la práctica pedagógica que se lleva a cabo en las escuelas técnicas. En tal sentido, el foco está en los espacios de las prácticas como dispositivo de acercamiento al mundo del trabajo. Este artículo se basa en un estudio cualitativo a partir de un estudio de casos en escuelas técnicas, durante los años 2015-2017. Sostenemos, desde las normativas, que las prácticas profesionalizantes constituyen una práctica fundamental en la educación secundaria técnica que se configura como espacio “por excelencia” en el vínculo con la formación para el trabajo. Dicha formación implica la puesta en acto de saberes y capacidades en la configuración del perfil profesional que se forma. En tal sentido, como hipótesis de trabajo, sostenemos que existe una disputa entre los saberes en la formación del técnico. Nuestra intención es poder dar cuenta de cómo las escuelas procesan sus propias demandas y cómo canalizan las propias demandas del mundo del trabajo. Consideramos que las luchas por el sentido que existen al interior de las escuelas, sobre el vínculo educación y trabajo, se materializan en la práctica, en el cotidiano escolar. Las escuelas promueven, enseñan, viven, actúan sus propuestas —complejas, no lineales, contradictorias a veces— sobre el lugar de la escuela y el mundo del trabajo de modo singular.
A Quality Improvement Initiative: A Nurse Practitioner-Led Interdisciplinary Approach to Reducing Readmissions in the Subacute Population
Authors: Rovito Clare , Fagan Kathleen
Published: February 2022

Background

To decrease the 30-day Subacute Readmissions in an outpatient facility by using an Advanced Practice Nurse (APN) Project Leader while applying evidence based transitional care processes.

Objective

Determine the effects of APN leadership within the Interdisciplinary Team in the subacute setting.

Methods

Immersion of an APN as Project Leader over a 12-week period.

Results

Outcomes were divided into three groups. They were reorganized and analyzed. The new breakdown included patients readmitted plus hospice referrals (n = 5) and those not readmitted (n = 4). A significant difference in the 30-day outcomes as well as the LACE variable comorbidity scores t (4) = 2.95, p = 0.0418 were identified.

Conclusions

The 30-day readmission rates were decreased using hospice as a referral source. Application of the Lippitt’s Model of Planned Change and the use of the LACE Scoring Tool were instrumental to the success of this project.

Implications for Nursing

To improve optimal outcomes it is necessary for the APN/Doctor of Nursing Practice (DNP) and other healthcare professionals to engage in collaborative practices that result in effective policy changes. This quality improvement project restructured the existing Interdisciplinary Team processes to include the APN Project Leader with improved patient-centered outcomes.
Çayır Mera Alanlarının Yabancı Ot Florası Üzerine Bir Araştırma: Türkiye, Muş İli Meraları
Authors: DEMİR İbrahim , ÜNAL Murat
Published: February 2022

Bu çalışma ile, Türkiye’nin doğusunda yer alan Muş ilinin çayır-mera alanlarında sorun teşkil eden yabancı otların bilimsel olarak tespit edilmesi amaçlanmıştır. Bu amaçla Muş ili genelinde 37 çayır mera alanında arazi çalışmaları yapılmıştır. Saha çalışmaları sonucunda toplanan bitki örneklerinin lokasyon, habitat ve rakım gibi bilgileri kaydedilmiştir. Bitki taksonlarının tanımlanması için, “Flora of Turkey and the East Aegean Islands” eserlerinden faydalanmıştır. Belirlenen taksonlar tür düzeyinde değerlendirilmiş, yabancı ot türlerinin zarar şekilleri ilgili literatürlere göre kategorize edilmiştir. Yapılan bu çalışma sonucunda, Muş ili genelinde 22 familyaya ait 211 yabancı ot türü belirlenmiştir. En çok takson içeren familyalar Asteraceae (50 tür), Lamiaceae (36 tür), Cyperaceae (21 tür) ve Ranunculaceae (18 tür) olmuştur. Her bir yabancı ot türünün çayır mera alanlarında zarar şekilleri belirlenmiştir. Sonuç olarak, bazı alanlarda zararlı türlerin yoğun olduğu tespit edilmiştir. Bunun en önemli nedenleri arasında, ilkbahar erken otlatma, kontrolsüz ve kapasitesinin üzerinde yapılan otlatma sayılabilir.
Planes, Trains, and Automobiles: Use of Carbon Dioxide Monitoring to Assess Ventilation During Travel
Authors: Cadnum Jennifer , Alhmidi Heba , Donskey Curtis
Published: February 2022

Background: Travel poses a risk for transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other respiratory viruses. Poorly ventilated indoor settings pose a particularly high risk for transmission.  
Methods:  We used carbon dioxide measurements to assess adequacy of ventilation during 5 trips that included air travel. During selected parts of each trip that involved indoor settings, we monitored carbon dioxide levels every 1 minute and recorded peak levels and the number of people present. Carbon dioxide readings above 800 parts per million (ppm) were considered an indicator of suboptimal ventilation.     
Results: Carbon dioxide levels remained below 800 ppm during train rides to and from the airport and inside airports except in a crowded boarding area with ~300 people present. Carbon dioxide levels exceeded 800 ppm inside the airplanes, but the air was filtered with high efficiency particulate air filters. Carbon dioxide levels remained below 800 ppm in common areas of a hotel but exceeded 800 ppm in a hotel room with 2 to 3 occupants and in a fitness center with 3 people exercising. In restaurants, carbon dioxide levels increased above 800 ppm during crowded conditions with 24 or more people present and 75% or more seat occupancy.
Conclusion: Our results suggest that ventilation may be sufficient to minimize the risk for airborne transmission in many situations during travel. However, ventilation may be suboptimal in some areas or under certain conditions such as in hotel rooms or when restaurants, fitness centers, or airplane boarding areas are crowded. There is a need for larger scale studies to assess the quality of ventilation in a wide range of community settings.
Teknik dan Instrumen Penilaian Mah?rah Al-Qir?’ah di Tinjau dari Tingkat dan Tujuan Pembelajarannya
Authors: Tolinggi Syindi Oktaviani R , Wahyuningsih Erni
Published: February 2022

Penilaian dalam pembelajaran mah?rah al-qir?`ah perlu dilakukan guna mengetahui tercapainya tujuan pembelajaran. Adapun dalam melakukan penilaian, masih banyak ditemukan ketidaksesuaian teknik dan instrumen penilaian yang digunakan oleh pendidik. Padahal pendidik harus selalu memperhatikan teknik dan instrumen yang digunakan agar sesuai dengan tujuan pembelajaran yang telah dirumuskan sebelumnya, tingkat atau jenjang kemampuan peserta didik, keterampilan berbahasa yang sedang dipelajari, serta bentuk pembelajaran yang dilakukan. Karena teknik dan instrumen penilaian yang baik akan menentukan hasil belajar peserta didik yang sesungguhnya. Oleh karena itu, penelitian kepustakaan (library reseacrh) ini bertujuan untuk mengkaji teknik dan instrumen penilaian mah?rah al-qir?’ah ditinjau dari tingkat dan tujuan pembelajarannya. Sumber data penelitian ini ialah data primer dan sekunder yang berupa buku-buku, artikel jurnal dan lainnya terkait dengan tema penelitian ini.
Perancangan Jaringan NB-IoT Menggunakan Skema Standalone Frekuensi 900 MHz di DKI Jakarta
Authors: Ginting Melinda Br
Published: February 2022

Teknologi telekomunikasi celluler semakin berkembang dengan sangat pesat. Hal ini dapat dilihat dari semakin banyak nya jumlah user yang semakin bertambah dan menuntut operator untuk memberikan layanan akses secara maksimal dengan cakupan yang luas tidak hanya untuk mobile phone tetapi juga device. Berdasarkan kebutuhan tersebut hadirlah teknologi telekomunikasi terbaru dengan mendukung device Internet of Things yaitu Narrowband Internet of Things (NB-IoT). Pada tahun 2016 3GPP standarisasi untuk NB-IoT, teknologi yang mampu memberikan layanan device IoT, dengan cakupan yang luas, low data rate 50 kpbs, dan penggunaan daya 43 dB untuk Standalone. Pada penelitian ini frekuensi yang digunakan adalah frekeunsi 900 MHz dengan skema Standalone yang menggunakan bandwidth 200 kHz. Parameter yang dianalisa pada skripsi ini ialah performansi kapasitas terhadap user connected berdasarkan simulasi diperoleh jumlah user yang terhubung sebesar pada skema Standalone sebesar 109.933 device user. Throughput yang dihasilkan ialah 85 Mbps untuk skema Standalone. Performansi coverage yang dianalisa ialah nilai SINR yang diperoleh pada skema Standalone 4,73 dB. Nilai RSRP yang diperoleh dari simulasi ialah sebesar - 68,53 dBm untuk Standalone. Serta, nilai BLER yang dihasilkan untuk skema Standalone yaitu 0,03
Secondary employment and its role in obtaining higher medical education
Authors: Gorbenko A. V. , Andreev K. A. , Fedorin M. M. , Skirdenko Yu. P. , Nikolaev N. A. , Chernenko S. V.
Published: February 2022

The study objective is to examine the structure and characteristics of secondary employment of medical university students. The authors carry out a survey of students of Omsk State Medical University of the Ministry of Health of Russia by continuous questionnaire survey technique. The questions of the questionnaire were aimed at socio-demographic identification of students. 2 330 (59,6 %) respondents participated in the survey of 3 906 students studying in the organization. According to the survey results 24,7 % (576) of students of OSMU work in their free time, while 12,6 % (294) work in medical sphere. Employed students are more common among married respondents compared to unmarried ones (55,9 and 29,1 % respectively, χ2 = 55.53, p < 0.001, Pearson). There is a growing trend in the proportion of employed students from the 1st year to 5th year (11,9 and 41,8 %, respectively). The same dynamics is revealed in the proportion of employed respondents in medicine (4,4 and 28,8 %, respectively). Respondents studying at the Preventive Medicine Department are employed in the medical field significantly less likely than other departments (χ2 = 30,04, p < 0.001, Pearson). The share of employed OSMU students increases while moving up the educational ladder. At the same time, employed students are 2 times more common among married students. The proportion of employed students of the Faculty of Dentistry of the 3rd and 5th yersis much higher compared to other faculties. Medical and Preventive Faculty students show the lowest rates with respect to employment in the medical field in their free time.
Численное моделирование распространения ячеистых пламен в узком зазоре между пластинами
Authors: Борисов Виталий Евгеньевич , Borisov Vitaly Evgenyevich , Якуш Сергей Евгеньевич , Yakush Sergei Evgen'evich , Сысоева Елена Ярославна , Sysoeva Elena Yaroslavna
Published: February 2022

На основе численного решения уравнений многокомпонентного реагирующего газа в приближении малых чисел Маха представлена вычислительная модель горения предварительно перемешанной смеси в узком зазоре между параллельными
пластинами. Применяется алгоритм поблочного адаптивного измельчения сетки,
позволяющий достигать высокого разрешения в областях резкого изменения характеристик течения, в первую очередь вблизи фронта пламени. Использован детальный кинетический механизм горения метана в смеси с воздухом. Расчеты проводились с помощью разработанного авторами программного комплекса ParTCS-3D на
суперкомпьютере К-100, установленном в ИПМ им. М.В. Келдыша РАН. Продемонстрирована эффективность параллельной реализации разработанной численной методики. Проведены параметрические расчеты горения стехиометрической метановоздушной смеси, расстояние между пластинами варьировалось в диапазоне 3--6 мм.
Показано возникновение неустойчивости распространяющегося пламени, выражающееся в развитии ячеек на его фронте. При малой ширине зазора продемонстрировано погасание пламени вблизи источника зажигания. Получена расчетная зависимость видимой скорости распространения пламени от ширины зазора, свидетельствующая о более быстром распространении пламени в широком зазоре вследствие меньшего влияния вязкости и теплопотерь.
Disabled children and problems of their adaptation to the educational environment: current state of the problem
Authors:   N.I.Pirogov Russian National Research Medical University, Moscow, Russian Federation, Volynets G.V. , Khavkin A.I. ,   N.I.Pirogov Russian National Research Medical University, Moscow, Russian Federation
Published: February 2022

This literature review aims to provide a summary of Russian and foreign literature on the problems associated with teaching of disabled children in Russia and in Europe. We searched for studies analyzing a direct link between education and children's disabilities. Numerous studies have been conducted in the English-speaking countries and published primarily in noneducational journals. We describe the education system in England and differences in academic performance of children with disabilities and students without disabilities. We also discuss primary and secondary effects of disability that determine imbalanced academic performance among disabled and non-disabled students, as well as the impact of stigmatization on the educational route and life of disabled people. We present criteria that determine ability to learn in accordance with Russian legislation, as well as the section "education and application of knowledge" of the International Classification of Functioning, Disability and Health. The article provides some statistics on inclusive and special education, including information on the number of disabled schoolchildren in Russia as of 2020. We found that the majority of disabled children educated in regular schools are secondary and high school students. We described the division into 8 types of special correctional educational institutions in accordance with disability groups existing in Russia now. Conclusion. It is necessary to analyze the association between education and children's disabilities in order to optimize inclusion of disabled people into social life. Key words: children, disability, education, limitations in usual activities
Quality of life of boys with constitutional delay of growth and puberty before and after different treatments
Authors:   V.I.Razumovsky Saratov State Medical University, Saratov, Russian Federation, Filina N.Yu. , Bolotova N.V. ,   V.I.Razumovsky Saratov State Medical University, Saratov, Russian Federation, Cherednikova K.A. ,   V.I.Razumovsky Saratov State Medical University, Saratov, Russian Federation, Dronova Е.G. ,   V.I.Razumovsky Saratov State Medical University, Saratov, Russian Federation, Logacheva O.A. ,   V.I.Razumovsky Saratov State Medical University, Saratov, Russian Federation, Goncharova O.V. ,   I.M.Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation
Published: February 2022

Objective. To compare the quality of life of adolescents with constitutional delay of growth and puberty (CDGP) before and after hormonal therapy. Patients and methods. This prospective single-center study had two stages. At the first stage, we evaluated the quality of life of 67 boys diagnosed with CDGP (experimental group) and 30 healthy boys of the same age (control group) using the Pediatric Quality of Life Inventory – PedsQL™ 4.0. At the second stage, we performed repeated assessment of the quality of life of CDGP boys after medical stimulation of puberty. Results. We found that delayed sexual development and progressive stunting in boys with CDGP was associated with a significant decrease in the quality of life by all functional scales compared to their healthy peers. We observed significant differences between the subgroups upon the repeated assessment 6 months after treatment completion. Conclusion. Timely initiation of pharmacotherapy to start puberty improves the quality of life. Short courses of androgens were found to be the most effective treatment in adolescents with CDGP according to their dynamics of sexual development and quality of life. Keywords: androgens, quality of life, constitutional delay of growth and puberty (CDGP)
Necrotizing enterocolitis: current concepts of etiopathogenesis with an emphasis on microbiome and metabolomics
Authors:   Almazov National Medical Research Centre, Saint Petersburg, Russian Federation, Petrova N.A. , Kaplina A.V. ,   Almazov National Medical Research Centre, Saint Petersburg, Russian Federation, Khavkin A.I. ,   Yu.E.Veltischev Research Clinical Institute of Pediatrics, Pirogov Russian National Research Medical University, Moscow, Russian Federation, Pervunina T.M. ,   Almazov National Medical Research Centre, Saint Petersburg, Russian Federation, Komlichenko E.V. ,   Almazov National Medical Research Centre, Saint Petersburg, Russian Federation, Nikiforov V.G. ,   Almazov National Medical Research Centre, Saint Petersburg, Russian Federation, Sitkin S.I. ,   Almazov National Medical Research Centre, Saint Petersburg, Russian Federation,   I.I.Mechnikov North-Western State Medical University, Saint Petersburg, Russian Federation,   State Research Institute of Highly Pure Biopreparations of FMBA of Russia, Saint Petersburg, Russian Federation
Published: February 2022

Necrotizing enterocolitis (NEC) develops primarily in premature infants and is characterized by high mortality. The most significant factors of NEC pathogenesis are gut dysbiosis, bottle feeding, and excessive inflammation. The intestinal microbiota of premature infants is characterized by lower bacterial diversity, increased proportion of potentially pathogenic microorganisms (such as Proteobacteria, Enterobacteriaceae), and decreased abundance of anti-inflammatory commensal bacteria. Molecular mechanisms of NEC pathogenesis and intestinal dysbiosis involve immune disorders, including excessive TLR4 signaling in response to bacterial lipopolysaccharides, as well as metabolic dysfunction associated with prematurity, enteral nutrition, and changes in the functional activity of the microbiota. Comprehensive pathophysiological mechanisms underlying NEC require innovative approaches to their investigation, such as metagenomics, metabolomics, and proteomics. Identification of potential biomarkers of NEC development and progression using omics technologies is one of the most promising methods to study this pathological condition. Key words: biomarkers, gut dysbiosis, metabiotics, metabolomics, metagenomics, microbiome, necrotizing enterocolitis, probiotics, proteomics, etiopathogenesis
Treatment of giant abdominal teratoma in a 10-year-old girl
Authors:   Tyumen State Medical University, Tyumen, Russian Federation, Axelrov M.A. ,   Regional Clinical Hospital No 2, Tyumen, Russian Federation, Evdokimov V.N. ,   Tyumen State Medical University, Tyumen, Russian Federation, Sergienko T.V. ,   Regional Clinical Hospital No 2, Tyumen, Russian Federation, Kuzhelivskiy I.I. ,   Siberian State Medical University, Tomsk, Russian Federation, Sitko L.A. ,   Omsk State Medical University, Omsk, Russian Federation, Emelyanova V.A. ,   Regional Clinical Hospital No 2, Tyumen, Russian Federation
Published: February 2022

We report a case of giant mixed ovarian teratoma in a 10-year-old girl. The patient underwent surgery (laparotomy, ovarian tumor removal, right-sided salpingoovariectomy) on the third day after admission to hospital. The postoperative period was uneventful; the prognosis was favorable. A detailed description of the diagnostic and treatment stages would be particularly interesting for practicing surgeons. Key words: child, teratoma, ovary
Association between the health of young children entering preschool institutions and social status of families
Authors:   Kemerovo State Medical University, Kemerovo, Russian Federation, Drakina S.A. , Seliverstov I.A. ,   Kemerovo State Medical University, Kemerovo, Russian Federation, Perevoshchikova N.K. ,   Kemerovo State Medical University, Kemerovo, Russian Federation
Published: February 2022

Objective. To evaluate the health status of young children entering preschool institutions depending on the social status of their families. Patients and methods. This study included 375 children aged 2 to 3 years attending kindergarten No. 239 in Kemerovo. Mean age of children was 25.91 ± 2.52 months. All study participants were divided into several groups according to their social status: from two-parent families (TPF; n = 339), including those with registered marriage (RM; n = 258) and unregistered marriage (UM; n = 81), and from single-parent families (SPF; n = 36), including those living with divorced mothers (DM; n = 25) and single mothers (SM; n = 11). Results. Women living with their partners outside marriage had significant changes during their pregnancy, at the time of breastfeeding and introduction of complementary foods; every fourth woman smoked. Every third child from two-parent families with an unregistered marriage had group III health (p = 0.0298). Vegetative complaints were significantly more common in families with divorced parents and unregistered marriage. Conclusion. Measures to promote healthy marriage and family relations should be implemented by teachers and psychologists at schools, other organizations for children and adolescents, specialized secondary and higher educational institutions. Key words: infants, health, single-parent family, two-parent family, social status
SELECTION OF THE OPTIMAL ENDOSCOPIC TREATMENT OPTION FOR PATIENTS WITH CHOLEDOCHOLITHIASIS
Authors:   Interregional Clinic and Diagnostic Center, Russia, Kazan, SAYFUTDINOV ILYAS M. , KRASILNIKOV DMITRIY M. ,   Kazan State Medical University, SLAVIN LEV E. ,   Kazan State Medical Academy, KHAYRULLIN RUSTEM N. ,   Interregional Clinic and Diagnostic Center, Russia, Kazan, ZIMAGULOV RUSTEM T. ,   Interregional Clinic and Diagnostic Center, Russia, Kazan, PANASYUK MIKHAIL V. ,   Interregional Clinic and Diagnostic Center, Russia, Kazan
Published: February 2022

Introduction. When using traditional endoscopic methods of choledocholithiasis treatment, the issues related to the remaining high risk of post manipulative complications remain unsolved. The priority task is the development of new methods of endoscopic treatment, which will prevent the development of postoperative complications. Aim. The aim of the study was to determine the optimal treatment option based on the comparative analysis of different ways of endoscopic interventions in patients with choledocholithiasis. Material and methods. The paper presents the outcomes of endoscopic interventions in 127 patients with choledocholithiasis. Of them 84 patients composed the main group in which choledocholithiasis treatment was performed according to the original method including two operative stages. On the first one we performed partial papillotomy, temporary stenting of common bile duct (in 100%) and main pancreatic duct (in 45%), and papillotomy over the stent to the muscular layer of Oddi sphincter. On the second one after 2–4 days the biliary stent was removed, lithoextraction was performed along with bile duct restenting. Pancreatic and biliary stents were removed after 24 hours and 3–8 weeks respectively. A comparison group was composed of 43 patients who underwent endoscopic surgeries by the classical well-known methods. Results and discussion. The analysis showed that the differences in the groups with classical method of choledocholithiasis endoscopic treatment (CMCLET) and original method of choledocholithiasis endoscopic treatment (OMCLET) between the levels of «Average number of surgeries per patient» (2,05 surgeries ranging from 1 to 4 for CMCLET versus 2,41 surgeries ranging from 2 to 5 for OMCLET; p=0,0176) and «Duration of hospitalization» (10,4 days to 8,95 days; p=0,0377), there was an inverse relationship between the number of surgeries and duration of hospitalization, which was largely due to different levels of the rate of early postoperative complications (p=0,0005). Twenty times higher blood amylase levels in the main group compared to the reference values did not lead to the development of acute pancreatitis, the incidence of which was 7 times lower in the comparison group (p=0,001). Conclusion. Comprehensive study of the outcomes of endoscopic treatment in patients with choledocholithiasis using different variants of interventions has shown convincing superiority of the original method of surgical aid.
COMPARATIVE STUDY OF THE EFFECT OF INSULIN-DEPENDENT DIABETES MELLITUS TYPE 2, HEREDITY AND SMOKING ON THE SEVERITY OF CORONARY HEART DISEASE
Authors:   Azerbaijan Research Institute of cardiology named after J.M. Abdullayev of TABIB Association, ALEKBEROV ELMAN Z. , MAMEDRZAYEVA VAFA M. ,   Azerbaijan Research Institute of cardiology named after J.M. Abdullayev of TABIB Association
Published: February 2022

Introduction. The presence of high-risk factors such as hereditary burdening, tobacco smoking, and diabetes mellitus significantly worsen the prognosis in potentially healthy individuals by increasing the incidence of coronary heart disease. Aim. To study the separate influence of insulin-dependent diabetes mellitus type 2, heredity and smoking on the severity and course of coronary heart disease. Material and methods. One hundred patients with coronary heart disease were enrolled in the study. The patients were divided according to the presence of the following high-risk factors: heredity, tobacco smoking, and insulin-dependent type 2 diabetes mellitus. The patients were examined at the beginning and 1 year after treatment. The results of echocardiography and electrocardiography were analyzed at the beginning of follow-up and one year later. The severity of coronary artery lesions was assessed using SYNTAX score analysis of coronarography protocols. The number of Q and QS waves on electrocardiogram, increased size and decreased left ventricular ejection fraction were also considered as criteria of coronary heart disease severity. The obtained data were processed using IBM Statistics SPSS-26 program. The differences were considered statistically significant at p<0,05. Results and discussion. Patients with diabetes mellitus were more susceptible to aortocoronary bypass grafting, whereas coronary angioplasty was performed more frequently in patients with heredity (p<0,05). Coronary vessels were more affected in diabetic patients and in tobacco smokers compared with patients with a burdened heredity [(20,4±2,7) points (21,9±1,39) and (12,9±1,8) points, respectively]. Severe heart failure prevailed among patients with concomitant diabetes mellitus. After one year, all patients had a reduction of clinical symptoms of angina and heart failure. The efficacy of medical treatment of angina in patients with heredity was lower compared to other groups. Conclusion. In patients with a history of diabetes mellitus development of coronary heart disease is manifested by severe myocardial and coronary lesions, which increases the risk of coronary artery bypass grafting. Despite this, patients with diabetes mellitus lend themselves well to drug treatment. The tobacco smoking group is not inferior to the diabetes mellitus group by the severity of heart and coronary artery lesions and is well amenable to drug therapy. The last place in the severity of coronary heart disease is occupied by patients with a hereditary burden, although they are more prone to acute coronary syndrome.
Analisis Penyebaran Penyakit Covid-19 dengan Pengaruh Pengobatan Isolasi Mandiri dan Pengobatan Perawatan Rumah Sakit (Studi Kasus Penyebaran di DKI Jakarta)
Authors: Adam Victorio Alexis  , Fariani Hermin Indiyah  , Eti Dwi Wiraningsih
Published: February 2022

In this research, a model for the spread of Covid-19 will be built using a differential equation because in the population there are two subpopulations who can spread the disease, there is one subpopulation who go through incubation period, and there are also 2 subpopulations who go through the treatment so the model will consists of compartments such as susceptible, exposed, asymptomatically infectious, symptomatically infectious, treatment 1 (self-isolation), treatment 2 (hospital care), and recovered. Analysis begins by calculating the disease-free equilibrium and endemic equilibrium. Before stability analysis, the model must be checked for adequacy in describing the disease spread. Stability analysis begins by forming the next generation matrix of the model with helps of jacobian matrix and chracteristic equation, then we can get basic reproduction number. By entering the value of parameters according to data to the basic reproduction number, we get reproduction number is 0,851115. The size of reproduction number means that the disease will disappear from the population.
Pemodelan Geographically Weighted Regression Menggunakan Pembobot Kernel Fixed dan Adaptive pada Kasus Tingkat Pengangguran Terbuka di Indonesia
Authors: Ramadayani Mila Rizki , Fariani Hermin Indiyah  , Ibnu Hadi
Published: February 2022

Unemployment Rate (UR) is an indicator for measuring the unemployment. Increase in the number of TPT in Indonesia by 1.84%, this is due to the impact of the covid-19 pandemic. analysis to find out the factors that affect TPT in Indonesia is by using multiple linear regression. The results showed that the data contained heterokedasticity and spatial aspects. Spatial data analysis continued with the point approach is by the Geographically Weighted Regression method (GWR). GWR is a weighted regression that results in a model that is local. GWR modeling uses weighting kernels Fixed Gaussian, Adaptive Gaussian , Fixed Bi-Square, and Adaptive Bi-Square produces that GWR Adaptive Bi-Square better, review value of the R2,AIC and JKG. The ability of the GWR model explains the effect of UR on factors (Labor Force or economically active, Health Complaint and Poverty Percentage) by 89.1%.
Dynamic Evaluation and Analysis of Regional Innovation Capability in Eastern China from the Perspective of High-quality Development
Authors: Xu Linming , Lu Jincheng , Li Meijuan , He Lerong
Published: February 2022

The economy of China has turned to the stage of high-quality development. In this sense, the connotation of regional innovation capacity should reflect more aspects, such as better economic effectiveness, people-centered philosophy of development and better living conditions. This study aims at establishing the evaluation index system of regional innovation capacity under high-quality perspective. Then the dynamic evaluation method based on gray correlation degree and TOPSIS is improved. And the improved method is applied to evaluate the regional innovation capacity under high-quality development perspective. The results show that: 1) The regional innovation capacity of Jiangsu, Zhejiang, Shanghai and Guangdong under high-quality development perspective is better than other regions, while the regional innovation capacity of Beijing-Tianjin-Hebei is imbalanced. Regional innovation capability of Fujian, Shandong, and Hainan from a high-quality perspective is at the middle and lower levels. 2) From the perspective of development trends, the gap of regional innovation capacity between Beijing, Jiangsu, Zhejiang, Shanghai, Guangdong and Fujian, Hebei, Shandong is gradually narrowing. 3) An in-depth analysis of the regional innovation capability of the eastern provinces and cities from the perspective of high-quality development through different dimensions shows that Beijing, Guang-dong, Jiangsu perform well in all dimensions, while Fujian and Hainan need to pay more attention to innovation input and the creation of a better innovation environment to enhance innovation output and promote innovation effectiveness. At last, based on above analysis, relevant policy recommendations are proposed.
Affordances de ressources numériques pour développer des littératies multiples en langues secondes : quatre études de cas
Authors: Hamel Marie-Josée , Auyeung Sarah , Bedou Stéphanie , Ding Yiran , Mongrain Catherine
Published: February 2022

Cet article met en valeur, à travers quatre études de cas, les affordances de ressources numériques pour élaborer des tâches langagières permettant de développer des littératies multiples en langues secondes. On y porte une réflexion sur les apprentissages hybrides et en contextes ouverts tout autant que sur la construction identitaire et l’autonomie en langue seconde. Des recommandations techno-pédagogiques sont formulées à l’intention des enseignants de langues secondes pour un usage optimal, notamment créatif et socio-interactif, des tâches et des ressources numériques présentées.
Partenariat rémunéré entre une entreprise et une influenceuse sur les réseaux sociaux : entrecroisement des voix des femmes autour de l’alimentation des nourrissons
Authors: Bayard Chantal , Charton Laurence
Published: February 2022

Les réseaux socionumériques (RS) ont transformé le rapport des femmes enceintes et nouvellement mères à l’alimentation des nourrissons. Ces dernières investissent ces plateformes (Facebook, Instagram, Twitter) pour obtenir et échanger de l’information ou du soutien, partager leurs expériences et s’engager socialement, notamment sur l’alimentation des nourrissons (allaitement et préparation). Les RS peuvent ainsi s’appréhender comme les dépositaires de voix diverses, qui s’expriment de multiples façons (textes, images, vidéos), aux intensités variables. Notre analyse des voix porte sur les réactions des utilisatrices sur Facebook et Instagram (740 commentaires) à la suite de la publication d’un billet de blogue rédigé par une influenceuse québécoise en partenariat avec une entreprise qui commercialise des préparations pour nourrissons. Dans un contexte où l’allaitement est recommandé par les autorités de santé publique québécoises, comment ce type de partenariat est-il accueilli? Quelles sont les voix qui émergent? Comment les voix de ces femmes s’entrecroisent-elles, se répondent/s’opposent/s’unissent-elles? De notre corpus émergent trois types de voix, celles du « mécontentement ou de la contestation », de « l’expérience » et de l’ « approbation ». En conclusion, nous suggérons que les voix des femmes, indépendamment de la méthode d’alimentation pour nourrisson utilisée, devraient être entendues et faire l’objet d’une plus grande attention de la part des autorités de santé publique de façon à protéger leur bien-être physique et émotionnel.
The Produced Water Conundrum Grows Across Unconventionals
Authors: Wright Blake
Published: February 2022

Shale players have a love-hate relationship with water. It’s an essential ally going into downhole to help proliferate fractures in the subsurface and free up stuck hydrocarbons. It’s a parasite coming out - a briny byproduct that can easily outpace oil production from any given well.

Likewise, operators must deal with water management on dual fronts. The first is sourcing the water to be used in the fracturing of the well. Second is finding the right solution for the flowback and formation water coming out of the well. Early on, the answer for the former was freshwater sources. However, once the strain set in from general scarcity, drought, environmental concerns or the like, industry started looking hard at the recycle and reuse of produced water - a solution where the problem becomes the answer.

Water recycling rates vary widely between unconventional basins. For the domestic oil industry, data provider IHS Markit forecast in an April 2020 report the vast majority of wastewater leaving an oil field in 2022 will still not be recycled. It will instead be injected into disposal wells, which is currently the most common practice for produced water management. This option is costly and risky, especially for wells that are located some distance from the nearest disposal well. It has also come under increased scrutiny because of the potential effects of disposal well use on the surrounding area’s seismic activity.

“Going back to the beginning of unconventional resource production, the focus was understandably on the water needed for drilling and completions,” Paola Perez-Pena, a principal researcher at IHS Markit, commented in an analysis. “Now that there is a considerable, established production, operators are realizing the extent to which produced water is not only a sizable matter, but an ongoing and essentially, perpetual one.”

Produced water is a mix of the water pumped down the well to assist with fracturing plus residual drilling fluid and formation water. On average, with every barrel of oil produced in the US, more than 4 bbl of wastewater is produced, though that number varies from basin to basin.

“With water, what you find is producers consider a number of different piping configurations, storage, and disposal well options, as well as reuse opportunities,” said John Walsh, principal technologist for Worley Advisian and author of the book, Produced Water. “There’s no one single strategy or approach that’s going to solve the water problem. There is no silver bullet.”

According to an industry brief by Raymond James in July 2019, pre-pandemic US oilfield water production was already a whopping 50 million BWPD. For scale, this amount of water could cover more than 8,000 football fields with a foot of water, every day. The investment bank estimated just under half of the total produced water came from horizontal basins, despite making up close to 80% of onshore crude production. The report forecast that the total volume of produced water from major oil basins in the US could grow to more than 60 million BWPD by 2030 (Fig. 1).
Technology Focus: Mature Fields and Well Revitalization (January 2022)
Authors: Marathe R. V.
Published: February 2022

The highlight of this year’s feature on mature fields and well revitalization has been the increasing use of artificial intelligence (AI) and machine learning (ML) for analysis of mature assets. Many paper proposals studied using AI/ML techniques cover a wide range of topics including optimization of production operations, faster reservoir characterization of mature fields, and improvement of ongoing waterfloods. In fact, increased use of AI/ML has been a recurring theme in many of the areas covered in the Technology Focus sections of 2021’s JPT issues. There has also been a focus on implementing novel technologies such as the use of autonomous inflow-control devices in horizontal wells to suppress ingress of unwanted fluids in thin-oil-rim reservoirs, using integrated-asset models for debottlenecking, and the use of cased-hole logging in old wells to look for missed opportunities.

After serving for 5 years, my time for writing this column is coming to an end. It has been

a highly rewarding exercise going through the paper proposals, experiencing the hard work put in by industry professionals to arrest inevitably declining production from mature assets by putting together ideas in diverse ﬁelds such as reservoir management, production optimization, drilling, and formation evaluation to produce the extra barrel from mature brownﬁelds.

Out of the 314 paper proposals studied in these 5 years, 137 (44%) dealt with waterﬂood improvement, reservoir characterization, and simulation, and approximately 78 papers (25%) dealt with well revitalization involving workover drilling, completion, and stimulation. Sustaining production from mature brownﬁelds challenges the best from each discipline, and signiﬁcant success stories have come from a genuine collaboration of ideas across disciplines from subsurface to engineering.

Recommended additional reading at OnePetro: www.onepetro.org.

SPE 206195 - Data-Driven Optimization of Intermittent Gas Production in Mature Fields Assisted by Deep Learning and a Population-Based Global Optimizer by Javier Fatou Gómez, TNO, et al.

SPE 205546 - Role of Geomechanics in Identification of Possible Mechanisms for Nonproductive Time and Improving Drilling Operations in a Mature Field in Offshore Sarawak, Malaysia by Avirup Chatterjee, Baker Hughes, et al.

SPE 206303 - Combining Capacitance Resistance Model With Geological Data for Large Reservoirs by Davud Davudov, Resermine, et al.
Cementless Well-Construction Possibilities Offer Cost, Emissions Reductions
Authors: Carpenter Chris
Published: February 2022

This article, written by JPT Technology Editor Chris Carpenter, contains highlights of paper SPE 206052, “Cementless Well Construction Opens Full Control of Well Integrity for the Life of the Well,” by Catalin Teodoriu, SPE, and Opeyemi Bello, University of Oklahoma, and R.R. Vasquez, Welltec, et al. The paper has not been peer reviewed.

Well construction has relied on two main elements—casing and cement—to achieve well goals while maintaining the highest possible well integrity. Can cementless well construction achieve similar goals? The complete paper investigates various well-construction concepts and analyzes the ability of cement to withstand long-term well loads.

Introduction

Well integrity is a fusion of several disciplines with the ultimate purpose of preventing well-control incidents during the life cycle of the well. The best chance of minimizing well integrity challenges is during the well-construction phase. In a situation in which the basis of design has established discrete criteria, however, any associated modiﬁcation must be highly controlled because failure to do so may have an ultimately detrimental eﬀect on long-term well integrity. In its simplest deﬁnition, well integrity denotes the ability of a well to produce or inject ﬂuids in a controlled manner while preventing any unwanted ﬂuid migration outside the well system.

Previous studies revealed that the integrity of well barriers is aﬀected signiﬁcantly by the degradation of drilling and completion ﬂuids, cement, and tubular materials. The main causes of well integrity loss are a lack of understanding of downhole conditions, temperature changes in casing ﬂuids (inducing casing expansion and contraction) imposing stresses on the cement/casing interface, inappropriate well-construction practices, poor selection of casing material and cementing type, and inadequate design veriﬁcation and validation of the downhole specimen.

The cement sheath is not always able to deliver an acceptable long-term solution for demanding drilling environments. Recently, advances in cement and well-completion practices have improved the quality of wells signiﬁcantly and have extended their operational life.

This paper presents a novel technology based on metal expandable packers (MEP) that enables cementless annular isolation across highly layered formations, providing long-length openhole zonal isolation to replace traditional cement operations, leading to signiﬁcant time savings and operational eﬃciency in the overall well- construction process and securing better economic return on the wells.
Machine-Learning Techniques Characterize Source-Rock Images at the Pore Scale
Authors: Carpenter Chris
Published: February 2022

This article, written by JPT Technology Editor Chris Carpenter, contains highlights of paper SPE 208632, “Reconstruction and Synthesis of Source-Rock Images at the Pore Scale,” by Timothy Anderson, SPE, Stanford University. The paper has not been peer reviewed.

Nanoimaging techniques for characterizing pore-scale structure of shales trade oﬀ between high-resolution/high-contrast sample-destructive imaging modalities and low-contrast/low-resolution sample-preserving modalities. Acquisition of nanoscale images also is often time-consuming and expensive. In the complete paper, the author introduces methods for overcoming these challenges in image-based characterization of the fabric of shale source rocks using deep-learning models.

Introduction

A promising application of data-driven scale-translation techniques is nanoscale imaging. This application is important for studying shales because of the importance of nanoporosity in shale gas storage. Nanoimaging techniques, however, present speciﬁc challenges and can result in small image data sets that do not allow for accurate quantiﬁcation of petrophysical or morphological properties. Consequently, data translation and generation both oﬀer many opportunities to assimilate multiple nano- and microscale modalities and to overcome limitations of nanoimaging systems.

The author proposes an image-based characterization work ﬂow (Fig. 1) for data-driven scale translation that uses deep-learning image synthesis and translation models to assimilate multimodal, multiscale, and data-scarce source-rock images for predicting petrophysical and morphological properties. A central challenge in source-rock characterization addressed in this work is the reconstruction of 3D volumes when only 2D training images are available. Image-translation models are presented for reconstruction of 3D image volumes from 2D training data and a porous media image-synthesis algorithm that generalizes to 3D grayscale and multimodal volume generation from 2D training data. The complete paper describes the translation and synthesis models, applies these models to source-rock image data sets, and discusses extensions and future directions for the introduced work ﬂow.
The causal relationship between sleep traits and the risk of schizophrenia: a two-sample bidirectional Mendelian randomization study
Authors: Wang Zhen , Chen Miao , Wei Yin-ze , Zhuo Chen-gui , Xu Hongfei , Li weidong , Ma liang
Published: February 2022

Background: Observational studies suggest that sleep disturbances are commonly associated with schizophrenia. However, it is uncertain whether this relationship is causal. To investigate the bidirectional causal relation between sleep traits and schizophrenia, we performed a two-sample bidirectional Mendelian randomization (MR) study with the fixed effects inverse-variance weighted (IVW) method. Methods: As genetic variants for sleep traits, we selected variants from each meta-analysis of genome-wide association studies (GWASs) conducted using data from the UK Biobank (UKB). Results: We found that morning diurnal preference was associated with a lower risk of schizophrenia, while long sleep duration and daytime napping were associated with a higher risk of schizophrenia. Multivariable MR analysis also showed that sleep duration was associated with a higher risk of schizophrenia after adjusting for other sleep traits. Furthermore, genetically predicted schizophrenia was negatively associated with morning diurnal preference and short sleep duration and was positively associated with daytime napping and long sleep duration.Conclusions: Therefore, sleep traits were identified as a potential treatment target for patients with schizophrenia.