bluuebunny/crossref_metadata_2025 huggingface dataset:
Composition and Antioxidant Activity of Aqueous Extracts Obtained from Herb of Tansy (Tanacetum Vulgare L.)
Authors: Mot Claudia Anca , Lupitu Andreea I. , Bungau Simona , Iovan Ciprian , Copolovici Dana Maria , Purza Lavinia , Melinte (Frunzulica) Carmen Elena , Copolovici Lucian
Published: February 2020

The aim of this study was to determine the phenolic content and antioxidant activity of extracts obtained from herb of Tanacetum vulgare L. (tansy) harvested in two different locations from the western part of Romania. Aqueous extracts of tansy presented high antioxidant activity that ranged between 295.77 and 653.65 mg GAE/L, and remarkable percentage of inhibition (31.82-65.05 %). The compounds quantified in the plant extracts that were determined by UHPLC are: ascorbic acid, riboflavin, pyrocatechol, rutin, quercetin, and kaempferol. Extracts obtained from tansy flowers showed higher content of phenols compared to that obtained from leaves. Similarly, the flower extracts present a high antioxidant activity that could suggest their use as natural additives in food preservation and also in pharmaceutical industry and veterinary medicine.
Research on the Recycling of Pulverulent Waste from the Ferous and Non-Ferrous Industry in Order tu Reduced the Pollution
Authors: Butnariu Ilie , Constantin Nicolae , Dobrescu Cristian , Heput Teodor
Published: February 2020

Research conducted and presented in this paper have sought to reduce the pollution of the environment by harnessing the red sludge, waste ferrous powdered alumina factories existing areas. The red mud is a waste derived from the production of alumina due to the fact that the raw material bauxite contains besides Al2O3 and other minerals such as: hematite, quartz, calcite, rutile titanium dioxide, clay, and shows the red color due to hematite, the whose content can reach up to 45-50% (or 31-35% Fe). Because mineral constituents, containing red mud and water of constitution (approximately 10%). The valorification of red mud in metallurgy is not resolved so far appropriately in terms technical-economical, due primarily to the high content of arsenic than the limit allowed to minerals, which leads to storing it in ponds or throwing by some manufacturers in the sea. This waste has been processed along with other ferrous scrap, are still able powdery or petty, but having a content almost double iron (powder steel mill, mill scale, sludge from agglomeration - furnaces) in order to increase the concentration of iron and decrease the concentration of arsenic by-product.
New Approach for Chemical Homogeneity Analysis of an AISI 316L Stainless Steel Bar Batch
Authors: Pencea Ion , Branzei Mihai , Turcu Ramona Nicoleta , Sfat Catalin Eugen
Published: February 2020

A batch of AISI 316L stainless steel bar was produced for orthopedic implant manufacture. The paper purposes a documented chemical homogeneity analysis (CHA) as a mandatory step of the chemical composition compliance practice for metallic bulk biomaterials. The CHA significantly diminishes the type II error risk. In this regard a new procedure was developed for CHA based on ASTM E826 one. The paper support the adequacy of the information mass assigned to spark discharged in argon-atomic emission spectrometry (SDAR-AES) technique. The case study demonstrates the power of this practice to discriminate among the homogenous elemental distribution (Cr, Ni, Si, etc) and heterogeneous (C, P, S).
Iono-molecular Separation with Composite Membranes V. Nitro-phenol separation on n-alkyl alcohols supported liquid membranes
Authors: Din Ion Spiridon , Cimbru Anca Maria , Abdalraheem Al Ani Hussam Nadum , Nafliu Ion Marius , Tanczos Szidonia Katalin , Nechifor Gheorghe
Published: February 2020

In this work are ongoing recent related studies on the separation of nitrophenols by composite membranes using this time an HFCLM membrane based on n-lower alkyl alcohols (C6, C8 si C10) on a well-characterized tubular polypropylene support . The results of nitrophenol separation, at a concentration of 5 mg / L in the source phase of pH 4.8, indicate the following optimal parameters of hydrodynamic regime, solvent and pH: source phase flow of 4.0 L / min, receiver phase rate 0.3 L / min; n-octanol, membrane solvent; the pH of the receiving phase that ensures maximum separation efficiency between 10 and 11; pH that ensures selective separation of m- and p-nitrophenols from m-nitrophenol between 8 and 10.The efficiency of nitrophenol separation through polypropylene capillary polymeric n-alcohol composite membranes reaches more than 90% at established working conditions, but operation below pH 12 will be considered in order not to cause membrane instability on the support.
The Routine and Specialised Staining for the Histologic Evaluation of Autogenous Mandibular Bone Grafts An experimental study
Authors: Nimigean Victor , Poll Alexandru , Nimigean Vanda Roxana , Moraru Simona Andreea , Badita Daniela Gabriela , Paun Diana Loreta
Published: February 2020

Oral rehabilitation by dental implants is a routine treatment in the common dental practice, and volume reconstruction in cases of advanced alveolar ridge atrophy using bone autografts has become a frequently used therapeutic procedure. The study presents a histological evaluation of autogenous mandibular bone grafts integration in surgically created maxillary bone defects. Seven domestic adult dogs, Canis Familiaris were used in the study. Work methodology was established through maxillary and mandibular morphometry, the donor region being the posterior mandibular body, and the recipient region being the lateral body of the maxilla. In the experimental study, we simulated two bilateral maxillary bone defects, which were augmented with mandibular corticocancellous bone grafts. Biological samples containing the target areas were collected 90-100 days after grafting and the subsequent preparation method of the samples for histological analysis was the standard one.The histological results showed the successful integration and the beneficial effect of corticocancellous autogenous mandibular bone grafts applied in maxillary sites.
Evaluation of Serum Vitamin B12 Levels in Type 2 Diabetes Patients Metformin Treated
Authors: Gherasim Andreea , Cianga Petru , Anisie Ecaterina , Arhire Lidia Iuliana , Mihalache Laura , Nita Otilia , Gavril Radu Sebastian , Graur Mariana
Published: February 2020

Vitamin B12 deficiency is a condition characterized by neurological or haematological abnormalities, and may occur after treatment with metformin in patients with type 2 diabetes. We evaluated 119 patients with type 2 diabetes mellitus, treated with oral antidiabetic agents. The parameters evaluated were: vitamin B12 intake, anthropometric data, disease history, neuropathic complications evaluation (using MNSI), serum vitamin B12, glycated hemoglobin, erythrocyte indices. Vitamin B12 deficiency was defined at values below 194 pg/mL. We have found a prevalence of vitamin B12 deficiency of 13.9% in the patients treated with metformin (10.9% in all participants). B12 levels were not correlated with age, metformin dose or duration of treatment. Patients using B12 supplements had higher B12 serum levels (472.50 vs. 329.22, p � 0.05).
In Vivo Pilot Study Regarding the Effects of Amoxicillin on Blood Glucose Levels, Body Weight and Water Intake
Authors: Mihalas Eugeniu , Balan Adriana , Petcu (Sirghe) Ana , Gavrila Laura , Savin Carmen
Published: February 2020

Amoxicillin it is the most commonly prescribed antibiotic agent and the first intention in the short-term treatment of infections in children. The aim of this study was to assess the effects of amoxicillin/clavulanic acid (AMC) chronic administration on the laboratory mice�s body weight (BW), water intake and values of non-fasting blood glucose levels (n-FBG). Thus, twenty-eight C57BL/6 male mice, of similar age, randomly divided into a control and 3 treatment groups (n = 7) received subcutaneous injection, once per day, for 60 days. During the experiment the n-FBG, daily water intake, and BW changes were recorded every 10 days. The results of our study revealed that the chronic administration of AMC, at a concentration of 100 and 150 mg/kg BW/day, increased capillary n-FGB, and can be associated with a significant increase in the BW and daily water intake in mice.
Structural and Morphological Characteristics of Hybrid Nanomaterials Type Ascorbic Acid-hydrotalcite Used for Stimulating Salivary Secretion
Authors: Zegan Georgeta , Golovcencu Loredana , Cernei Eduard Radu , Carausu Elena Mihaela , Anistoroaei Daniela
Published: February 2020

A new hybrid nanomaterial type vitamin C/ZnAl-hydrotalcite, acting as drug delivery system for ascorbic acid, was developed in order to use it for stimulating salivary secretion. The synthesis of this nanomaterial was achieved using a simple coprecipitation method for intercalation of ascorbate anions in the ZnAl-hydrotalcite gallery. The stability of vitamin C was significantly increased after its incorporation into the interlayer space. Structural and morphological characterization techniques revealed an alteration of the pristine nanomaterial type ZnAl-hydrotalcite when vitamin C was loaded in its matrix. Structural and morphological analysis showed that ascorbate anions were intercalated in the interlayer of ZnAl-hydrotalcite having no effect on the hydroxide lattice of hydrotalcite, so this new nanomaterial can be used for the intended purpose.
Chemical Changes Caused by Calcium Deposition in Forestier - Rotes - Querrol�s Disease
Authors: Decusara Mioara , Romila Aurelia , Pavel Liliana , Andrei Lucian Laurentiu , Rusu Negraia Magdalena , Macovei Luana Andreea
Published: February 2020

Calcium is involved in many biological processes. Hydroxyapatite provides bone mineralization, maintains cellular signaling, enzyme activity, nerve impulse transmission, muscle contraction and regulates blood clotting and membrane permeability. Calcium depositions may be caused by necrosis following trauma, connective tissue diseases, metabolic diseases, sarcoidosis, myeloma, metastases, chondrocalcinosis or calcium pyrophosphate dihydrate crystal deposition disease, cervical spondylosis, ankylosing spondylitis, ossification of the posterior longitudinal ligament of the spine and Forestier�s disease. Diffuse idiopathic skeletal hyperostosis (DISH) or Forestier-Rotes-Querrol�s disease is characterized by calcification of ligaments and entheses of the anterior vertebrae in the thoracic spine and sacroiliac joint bridging caused by abnormal proliferation of osteoblasts. At least four consecutive thoracic vertebrae are affected and the intervertebral disc space is preserved. Peripheral joints of heels, knees, elbows and pelvis may be also affected. Diagnosis is confirmed by radiographic findings with a candlewax-like appearance down the spine, on C2-C6 vertebrae. A total number of 37 patients with a median age of 63 years, of which 24 were male (64.86%) and 13 female (35.14%), were diagnosed with DISH at the Clinic of Geriatry of Galati County Emergency Clinical Hospital Sf. Apostol Andrei between 2006-2016. Differential diagnosis included ankylosing spondylitis and spondylosis deformans. DISH was found in patients aged over 50 years, with obesity and diabetes, based on radiographic findings. Drug therapy and physical therapy successfully provided pain relief, increased axial and peripheral mobility, improved physical function and optimal quality of life. None of our patients required surgery, as there were no cases with compromised airways and digestive tract involvement. Our study confirms that old age, obesity and type 2 diabetes are risk factors for diffuse idiopathic skeletal hyperostosis.
The Role of Combining Biochemical Markers in Assessing the Endoscopic Activity in Ulcerative Colitis
Authors: Dranga Mihaela , Mihai Catalina , Gavrilescu Otilia , Cardoneanu Anca , Floria Mariana , Mihai Bogdan , Cijevschi Prelipcean Cristina
Published: February 2020

Ulcerative colitis (UC) isa chronic, idiopathic and recurrent inflammatory bowel disease (IBD), characterized by periods of activity and remissionwhose monitoring requires invasive explorations associated with discomfort for the patient and important costs. Mucosal healing became one of the most important therapeutic targets in UC. The aim of our study was to identify a score, made up of noninvasive, available, used in current clinical practice biochemical markers, which should correlate with endoscopic activity in UC. We conducted a prospective study on 114 patients with UC. All patients were assessed both for biological inflammatory markers: erythrocyte sedimentation rate (ESR),C- reactive protein (CRP), fibrinogen, platelets, albumin, fecal calprotectin (FC) and by colonoscopy to estimate the endoscopic activity using Mayo score. By linear regression, we tried to identify a biochemical score correlated with endoscopic activity. Out of the serological markers,ESR (p=0.014), CRP(p= 0.021) and fibrinogen (p=0.035) correlated with the endoscopic activity of the disease. The best sensitivity to determine the endoscopic activity was given by FC (96.05%) with a predictable negative value of 91.1% (p=0.001). The score determined by linear regression: 1 (ESR]15mm/1h) x 0.305 + 1(fibrinogen]340.5mg/dL) x 0.309+1 (CRP] 5 mg/L) + 1 (calprotectin]200 μg/g) had an increased positive predictive value compared to each and one biomarker, nevertheless, with a sensitivity and specificity inferior to that of FC. Up to now, it is the first attempt to achieve a score made up exclusively of biological markers. The obtained score, although with an increased accuracy, has proven to have a lower predictability in comparison with FC used individually and cannot entirely replace colonoscopy.
Risk Factors and the Mechanism of Induced Oral Cancer by the Chemical Substances
Authors: Stefanescu Ovidiu Mihail , Dragomir Raluca , Ciurcanu Oanaelena , Budacu Cristian Constantin
Published: February 2020

At this end of the millennium we witness an impressive increase in cancer frequency. According to WHO reports, cancer is the second cause of death, being overpriced by cardiovascular disease only. The oral cavity cancer is part of the ENT sphere malignant tumor group. It may appear at the level of any component structure: mobile tongue, mouth floor, retromolar trine (behind the last molar teeth in the lower arch), tough palate, internal cheek, lips, mouth vestibule or alveolar rebord. Salivary glands, although opening into the oral cavity, can not be included in this category, due to histological and enlargement features. Oral cancer is very easy to be noted because it causes a mouthstroke that does not heal over several weeks. This is the main symptom of the disease, but not the only one. Other signs are: whitish spots in the mouth, unexplained bleeding, difficulty in moving the jaw or chewing; hoarseness or considerable change in voice, loss of sensation or pain in the mouth, face or neck area, undue ear pain. The study includes 544 cases, and the statistical data collected over a 5-year period, 2013-2017, and: age, environment, sex, risk factors involved, location, tumor study and treatment are of interest. Combined therapy was reserved for patients with a low healing rate. The most common form of treatment was tumor removal within the limits of tumor safety, followed by another type of intervention: tumor extirpation and ganglion recording, whether or not associated with radiotherapy. An important role is also played by patients who come late, either due to a lack of health education or because of the fear of illness, or in most cases due to the oligosymptomatic character of the disease at the onset of onset.
Lamellar Tearing Observations Regarding the Application of European Standards in the Field of Welded Steel Constructions
Authors: Feier Anamaria , Chivu Oana Roxana
Published: February 2020

The problem of corrosion for old steel bridges in operation is often solved by direct replacement of elements or structure. Only a few studies have been done to determine the efforts influenced by corrosion in those elements. In general, it is considered that a corroded element has exceeded the bearing capacity and should be replaced, but if the corroded element is secondary it could be treated and kept. A factor in the rehabilitation of an old steel bridge in operation is the aspect of structure. If the structure is corroded, rehabilitation decision is taken is easier. Lamellar tearing describes the cracking that occurs beneath the weld and can be characterized as a brittle failure of steel, in the direction perpendicular to the plane of rolling. The paper presents a comprehensive study on lamellar tearing and summarizes some conclusions about the prevention of them. The conclusions will be exemplified in the case of a railway bridge, with a main truss girder. The paper presents also some observations regarding the stress analysis in fillet welds, resulting from the engineering practice.
Electrodeposition of CoNiMnP Thick Films for Micromachined Magnetic Device Applications
Authors: Barbu Paula , Codescu Mirela Maria , Iordoc Mihai , Marinescu Virgil , Manta Eugen , Ilie Cristinel , Popa Marius
Published: February 2020

CoNiMnP permanent magnetic alloys were electrodeposited on copper and brass substrates from a bath containing 26 g/L CoCl2�6H2O, 24 g/L NiCl2�6H2O, 3.6 g/L MnSO4, 4.6 g/L NaH2PO2�H2O as precursors and H3BO3, NaCl, saccharin, sodium lauryl sulphate and cerium(III) sulphate as additives. Influence of the presence of external magnetic field (2 T) was investigated using vibrating sample magnetometry and SEM/EDS microscopy.
Partially Defatted Pumpkin (Cucurbita maxima) Seeds - a Rich Source of Nutrients for Use in Food Products
Authors: Apostol Livia , Berca Lavinia , Mosoiu Claudia , Badea Mihaela , Bungau Simona , Oprea Oana Bianca , Cioca Gabriela
Published: February 2020

Pumpkin (Cucurbita maxima) seeds are a rich source of ingredients such as aminoacids, fatty acids, minerals, and phytochemicals exhibiting nutraceutical effects on human health. In this work, partially defatted pumpkin seeds flour, a by-product obtained during the manufacture of pumpkin seeds oil, was studied as an additive for common wheat flour. We explored the physico-chemical properties as well the content in amino acids of the partially defatted pumpkin seeds. The obtained results revealed that partially defatted pumpkin seeds are a good source of protein (42.75% d.m.), lipids (12.28% d.m.), total carbohydrates (37.4% d.m.), from which crude fiber (26.64% d.m.). This by-product presents a high mineral content (mg/100g): potassium (1290), magnesium (693), iron (87.8), zinc (11.5) and copper (2.49).The partially defatted pumpkin seeds proteins contain significant amounts of essential amino acids such as valine, histidine, isoleucine, leucine, threonine and methionine.
In vitro Behaviour of Alumina-Hydroxiapatite Composites Coatings
Authors: Szabo Alexandru , Bordeasu Ilare , Utu Ion Dragos , Mitelea Ion
Published: February 2020

Hydroxyapatite (HA) is a very common material used for biomedical applications. Usually, in order to improve its poor mechanical properties is combined or coated with other high-strength materials.The present paper reports the manufacturing and the biocompatibility behaviour of two different biocomposite coatings consisting of alumina (Al2O3) and hydroxyapatite (HA) using the high velocity oxygen fuel (HVOF) spraying method which were deposited onto the surface of a commercially pure titanium substrate. The biological properties of the Al2O3-HA materials were evaluated by in vitro studies. The morphology of the coatings before and after their immersing in the simulated body fluid (SBF) solution was characterized by scanning electron microscopy (SEM). The results showed an important germination of the biologic hydroxyapatite crystallite on the surface of both coatings.
Drug-Induced Sleep Endoscopy with Target-Controlled Infusion Using Propofol in the Management of Patients with Obstructive Sleep Apnea
Authors: Stefanescu Dragos Cristian , Hainarosie Razvan , Zainea Viorel
Published: February 2020

Although it seems to be an exhausted subject at first glance, the therapeutic approach in obstructive sleep apnea syndrome (O.S.A.S.) is still an open subject. The continuous positive airway pressure (C.P.A.P.) represents the gold standard of therapy in O.S.A.S. However, this therapeutic process with C.P.A.P. has a low rate of compliancy, over 50% of patients quit in the first year of use. Implicitly, surgical solutions or mandibular advancement devices remain an alternative for many of these patients. High costs, complexity and risks associated with surgery have led to the identification of more accurate methods for topographic and functional diagnosis in O.S.A.S. Drug-induced sleep endoscopy (D.I.S.E.) with target-controlled infusion (T.C.I.) using propofol in the management of patients with obstructive sleep apnea is a relatively recently introduced method in Romania. The present paper describes our experience with D.I.S.E for selected patients, who have undergone surgery on the upper airway for O.S.A.S. The D.I.S.E method has led to the modification of the initial surgical plan in over 60% of patients with multi-level obstruction. Under these conditions, the surgical success rate in patients of the study increased to 80% at 6 months. Considering the specific endowment of each tertiary sleep center, the presence or absence of an operator block and the anesthetist�s experience with target-controlled (T.C.I.) infusion using propofol, more extensive and multicenter studies are needed for standardization of D.I.S.E.
Moroctocog Alfa Efficacy in Hemostasis Management in A Type Hemophilia Patients with Elective Arthroplasty
Authors: Badulescu Oana Viola , Tudor Razvan , Friedl Wilhelm , Scripcaru Andrei , Sirbu Paul Dan
Published: February 2020

Type A haemophilia is a hereditary coagulopathy caused by coagulation factor VIII deficiency as part of the rare, life-threatening and at-risk group of diseases that has been attributed over time a life-saving substitution treatment providing to patients diagnosed with this pathology a hope for life and quality of life similar to that of healthy population. However, substitution treatment is very expensive so that nowadays globally most patients cannot benefit from proper healthcare. The quality of healthcare is dependent on the socio-economic level of each country, being decisively influenced by the power of the National Hemophilia Organizations to generate solidarity and support of decision-makers of each country. One of the bleeding manifestations specific to haemophilia is haemarthrosis. Each haemorrhagic episode causes locally a disorder that predisposes to relapse, with the onset of the main chronic complication of this condition, haemophilic arthropathy. It has a slow evolution throughout the life of the patient and generates in time severe sequelae (ankyloses) that require total arthroplasty. Effective hemostasis is the essential element for performing this type of orthopaedic surgery, due to bleeding risk that is of vital nature, in this category of patients. In this sense, this study aims to underline the efficacy of Moroctocog alfa in the management of haemostasis in haemophiliac patients with total endoprosthesis indication, aimed to reduce joint pain and improve locomotor function.
Oral-Facial Manifestations Caused by the Use of Psychotropic Medication in Psychiatric Patients
Authors: Caraiane Aureliana , Szalontay Andreea , Macovei Luana Andreea , Romila Aurelia , Indrei Lucian Laurentiu , Decusara Mioara , Tarc Tiberiu
Published: February 2020

The development of psychotropic chemotherapy with widespread use in the psychiatric clinic for its anxiolytic, hypnotic, antidepressant, psychostimulant or psycho-destructive sedative effects has given rise to a new pathology secondary to increased abuse and accessibility. Their neurotropism is generally exerted on the central nervous system at the level of the complex meso-diencephalo-striate structures, influencing the elementary psychic functions, but also the activity of the whole organism through the neuro-humoral system. The clinical investigation of the patient must be interdisciplinary in nature, as human beings are characterized by a bio-psycho-social unit, in which the various biological and psychological components, influenced to a greater or lesser extent by the social environment, are involved in a special way, which gives an original personality to everyone. There are five fundamental axes, which are usually evaluated: thinking, memory, attention, emotion and behavior. A disorder in any of these axes, intense enough to interrupt the normal activity in more than one operating field over a sufficiently long period of time, is diagnosable as a mental disorder. There is an indication borrowed from internal medicine regarding the acute character (weeks), subacute character (months) and chronic character (years), which is attached to the diagnosis. A small part of the entire psychiatric population suffers from severe conditions, which involve intermittent episodes of severe disinhibition, aggressive behavior and self- or hetero-directed violence. In most cases, we talk about conditions such as depression or anxiety disorders (panic disorder, phobias, obsessive-compulsive disorder), which do not make him a social predator, although they cause enormous suffering to the individual. This study includes 67 patients with mental illness. While conducting the study, we took into account that the first contact with the patient is essential for the results of the anamnesis, oral examination, risk assessment and provisional treatment plan. In the 67 cases there were performed mycological analyses. It is necessary that dentists have certain knowledge of psychology and psychopathology, in order to understand the mechanism of psychopathological reactions and avoid them.
Complex Analytical Investigations of Old Wax - sealed Romanian Paper Documents
Authors: Stirbescu Nicolae Mihail , Ion Rodica Mariana , Radu Adrian , Teodorescu Sofia , Bucurica Ioan Alin , Stirbescu Raluca Maria , Geba Maria , Dulama Ioana Daniela
Published: February 2020

Waxes as a component of seals, are recognized in our history as adhesives, for surface coating purposes, modeling or casting materials and also in conservation practice. The waxes with mineral, vegetable and animal origin should be connected to modern methods of analysis, due to their complex composition: long chain hydrocarbons, acids, alcohols, esters. They support many mechanical damages in library and archive collections: cracking, pieces lost by an excessive handling of documents. In this paper the compositional analyses of some wax seals belonging to some paper samples have been achieved by Raman spectroscopy and Fourier transform infrared spectroscopy (FTIR) - for molecular structural information of wax materials, by gas chromatography / mass spectrometry (GC/MS) - for evidence of some compounds resulted from degraded wax seal, and by optical microscopy (OM) and scanning electron microscopy (SEM) - for visualization of the damaging effect on the wax seal. All these analytical investigations have been achieved for wax seals detached from the paper samples recovered from two disaffected pulp and paper factories - Letea and Busteni (Romania) belonging to Romanian industrial patrimony.
Correlation of Oral Vitamin D Administration with the Severity of Psoriasis and the Presence of Metabolic Syndrome
Authors: Stanescu Ana Maria Alexandra , Grajdeanu Ioana Veronica , Iancu Mihaela Adela , Stoian Anca Pantea , Bratu Ovidiu Gabriel , Socea Bogdan , Socea Laura Ileana , Diaconu Camelia Cristina
Published: February 2020

To improve the management of psoriasis, we have started from the hypothesis that normalization of vitamin D serum reduces the severity of psoriasis and positively influences the diagnostic criteria of metabolic syndrome. Experimental part. The objective of the prospective study was to evaluate the impact of oral vitamin D on psoriazis and metabolic syndrome in a group of 184 patients diagnosed with psoriazis and metabolic syndrome, between 2010-2017. In all patients included in the study, we evaluated family history, personal medical history, the living and working conditions, the history of psoriatic disease (control group only), clinical data (waist circumference), height (cm), body mass index, blood pressure (mmHg)) and laboratory examinations. Regarding the severity of psoriasis, in all 141 patients treated with vitamin D, a significant improvement was seen after 12 months of treatment. We bring a new approach to the treatment of psoriasis with vitamin D.
The Relation of Body Mass Index to Biochemical Parameters and Profile of Heart Failure
Authors: Aursulesei Viviana , Manta Andrei , Namat Razan Al , Hugianu Monica , Moloce Angela Maria , Aursulesei Victor Cristian , Constantin Mihai
Published: February 2020

The bidirectional relation between body mass index (BMI) and heart failure (HF) is complex and not fully understood. The obesity paradox phenomena is controversial and related to patient selection, parameters used for defining abnormal weight, characteristics of HF. Our study sustain the importance of controlling risk factors, in particular plasma glucose, lipid levels, as well as hypertension in patients with HF and BMI over 25 kg/m2. Also, in contrast to the randomized control studies our results can only partially support data related to obesity paradox phenomena.
Synthesis and Structural Studies of Bismuth-piroxicam Complex
Authors: Kanwal Ayesha , Imran Muhammad , Iqbal Zafar , Rehman Summia , Danish Zeeshan , Batool Nayab , Mitu Liviu
Published: February 2020

Piroxicam [4-hydroxy-2-methyl-N-2-(pyridyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide] is an effective antiinflammatory analgesic drug. In the present work, piroxicam has been chemically modified into its bismuth complex by reacting it with bismuth nitrate at ambient conditions and optimized stoichiometric ratio. The synthesis of the complex has been monitored by TLC and characterized well by Fourier Transform Infrared (FTIR), UV-Vis, ICP, TGA, XRD and SEM. The luminescent behavior of this complex has also been studied which determined its photoluminescent property.
Evaluation of Bone Healing of Artificial Defects in Laboratory Animals After Covering with Alloplastic Material
Authors: Chivu Manuela , Tantar Cristian , Hutu Emilian , Comaneanu Raluca Monica , Rusu Elena
Published: February 2020

Bone defects are commonly seen in clinical practice. They are caused by different types of trauma, infections, congenital malformations and cancers. Current approaches to skeletal reconstructive surgery use biomaterials, autografts or allografts. The aim of this study was to analyze bone repair from histologic point of view. To study the repair of bone defects, we used two batches of Wistar mices (Lat Rattus Norvegicus). The 46 subjects under study were divided into two equal lots. In all subjects, a round defect with a diameter of 5 mm was surgically performed on the right and left parietal bone. In the 23 subjects in group I the defect in the left parietal bone was covered with alloplastic material (Osteoset) and the defect in the right parietal bone was not covered with osteoconductive, osteoinductive or osteogenic materials. Regarding subjects in group study II, none of the surgically created bone defects were covered with alloplastic materials. Euthanasia of the subjects included in the study was performed at 2 and 4 months respectively, at the time of surgery. Euthanasia, bone sampling and assembly for microscopic preparations were done on the same day. The histological analysis of a bone repair shows the direct correlation between the healing process and the addition of alloplastic materials (Osteoset).
Smoking Cessation in COPD Patients by a Selective Partial Nicotinic Agonist
Authors: Ianosi Edith Simona , Postolache Paraschiva , Macovei Luana Andreea , Szathmary Mioara , Szasz Simona , Nemes Roxana Maria , Jimborean Gabriela
Published: February 2020

The fight against smoking through various smoking cessation methods could be very effective by early education especially in young people for preventing the occurrence or the severity of obstructive lung diseases. The aim of the study was to present the impact of varenicline, a selective partial nicotine agonist, in adults of 40-49 year-old, active smokers, recently diagnosed with COPD, from 2009 to 2011, in a Smoking Cessation Center of the Pulmonary Rehabilitation Clinic Iasi, Romania. There were included all male employees, without occupational exposure, active smokers, with a personal history of smoking �10 packs-year cigarettes, recently diagnosed with COPD, who inform consented to be enrolled for counseling and smoking cessation treatment provided by varenicline. All patients received COPD therapy, according to the current GOLD recommendations. The method of evalution the impact of smoking cessation methods consisted in the COPD Assessment Test (CAT) completed by cases before and after 12 weeks program of smoking cessation counseling and therapy and respiratory rehabilitation. The CAT is a short questionnaire, simple and validated tool of COPD symptoms assessment, measuring the severity of COPD on a patient�s quality of life. Results reveals an important decreasing of CAT score with important amelioration of symptoms especially in severe COPD patients. Counseling, smoking cessation and respiratory rehabilitation interventions have shown positive effects of smoking cessation with varenicline among young COPD patients 40-49 year-old.
Chemical Processes in Endodontic Failure Due to Incidents and Accidents
Authors: Salceanu Mihaela , Iliescu Alexandru Andrei , Iliescu Andrei , Caraiane Aureliana , Scutariu Mihaela Monica , Melian Anca
Published: February 2020

The fundamental principle that must guide the activity of each dentist is the conservative, hence the task of preserving, as much as possible, the teeth in the arches, knowing what important injury brings extractions to the individual. An essential concern of endodontic therapy is the thorny problem of infected canals. At present, it is essential for any practitioner to recognize the relationship between microbial oral and pulpal and periapical tissue, the notions of endodontic microbiology being the key to understanding the basic methods of debriding, modeling and obstructing canals. Among the pathological conditions that overrun the clinical picture of pulp sickness, not only at the local and general level, the simple or complicated pulp gangrene has a well-established role. The endodontic treatment has three basic stages: diagnosis, preparation of the channel that follows the debridement, its modeling and sterilization, and the root filling. The rationale behind the treatment of this disease is that the devital pulp does not have defense mechanisms, the endocannicular microbial flora finding under these conditions a favorable environment of development. Regardless of the degree of expertize, the accumulated experience, the responsibility and the correctness of medical care, certainly no dental practitioner has been circumvented by failures in endodontic therapy. The relatively high percentage of failures has led to countless attempts to improve the tools and materials made available to the dentist. Currently, he faces a new problem, that of choosing the most correct method of endodontic treatment. Material and Method: The structure of the study material was 240 cases taken into account, from 2012-2017. Results and Discussion:Because endodontic therapy requires very precise working techniques, it implies rigorous records, both in terms of the sequence of treatment phases, but also in relation to some technical aspects - such as - data on root canals, the chronology of the radiological examinations, the instruments and the substances used - the neglect of the correct records resulting in unnecessary time losses and traumatisations of the periodontal-apical area.Conclusions: Starting from the assumption that the radiological examination is the only objective way of initial assessment of dental morphology, the certification of the existing pathology and the establishment of a diagnosis, the orientation of the treatment plan and the verification of the correctness of the therapeutic variant chosen through a monitoring of the results over time, we sought to clarify the actual role and the actual value of the radiological examination in endodontic therapy.
Body Mass Index, Follicle-Stimulating Hormone and their Predictive Value in vitro Fertilization
Authors: Stelea Lavinia , Petre Izabella , Craina Marius , Vlaicu Brigitha , Sisu Alina , Pop Elena , Moleriu Radu Dumitru , Ivan Mihaela Viviana , Novak Tibor , Fulger Lazar
Published: February 2020

The aim of this study was to determine if body mass can be considered a risk factor for infertility, and if we can find any correlations between the age values and the FSH and estradiol values, and between the BMI values and the FSH and estradiol values. Our whole sample contains 100 patients splinted in two groups (pregnant patients N1=57 subjects, 57%, and not � pregnant patients N1=43 subjects,43%). In the first part we conducted our analysis on the whole group and after that we focused the analysis on the two groups and we made some comparisons between the groups. We obtained a medium, extremely significant correlation in all scenarios between the age and the FSH values. This is the best association from all the cases which we tested. In all twelve cases we have a positive correlation (r ] 0). As well, we obtained that a BMI value higher than 25can be considered a risk factor for obtaining a pregnancy (p[0.05, RR ] 1, OR]1) . Our study shows that women who have weight problems have much less chances of conceiving a baby, even if they ovulate normally. The risk of infertility increases proportionally to the extra pounds. Irregular ovulation in women is the most common fertility disorder due to obesity disease.
Pregnancy Anemia as a Favorable Factor of Premature Birth
Authors: Oancea Alexandru , Stanescu Casiana , Anastasiu Popov Diana Maria , Neamtu Radu , Anastasiu Doru , Gluhovschi Adrian , Poenaru Marioara
Published: February 2020

Hematological physiological changes during gestation are intended to compensate and support pregnancy-related changes in the woman�s body. In pregnancy there is a dilution of the known Hb concentration known as gestational hemodilution or physiological pregnancy anemia. On a group of 300 pregnant women with different forms of anemia, we followed its implications on the evolution of pregnancy, its role in the determinism of premature labor, and its role in the apparition of intrauterine growth retardation. In 46 cases (15.33%) we reported premature births, in 23 (7.66%) of the cases we considered that anemia was the main (unique) cause of premature birth, in other cases (84.67%) anemia associated with other etiologic factors of premature birth. Comparing the incidence of preterm birth with a group of 300 pregnant women without anemia revealed the incidence of premature birth is 3 times less and is represented by 12 cases (4%) and 2 times less for intrauterine growth retardation represented by 16 cases (5.33%). Pregnancy anemia can cause a frequent pathology with major consequences in pregnancy development during birth and fetal development involving 15.33% of preterm births and 12.35% of cases of intrauterine growth retardation. In the current social and economic context, it is necessary to prophylactically administer iron for pregnant women from 20 weeks of gestation, at least 30mg / day for prophylaxis of pathology due to iron deficiency.
Evaluation and Completion the Design Methods of Pressure Vessels Flange Joints
Authors: Jinescu Valeriu V. , Urse Georgeta , Chelu Angela
Published: February 2020

We have provided a comparative analysis of the current international computing standards (European Standard EN 13445-3; ASME-Code, Section VIII, Division 2; British Standard (PD 5500: 2009)) that take into consideration only the static loading of flanges and bolts, if the temperatures of the flanges, bolts and sealing gasket are equal to each other and lower than creep temperature. The paper has put forth relations for completion the calculation method for flange joints in situations not taken into consideration by standards, namely: � static loading if flange temperature and bolt temperature are different; -thermal transient loading; � creep stress; � fatigue loading in the general case of a sequence of blocks of normal stresses. Furthermore, relationships have been proposed for the calculation of the maximum allowable difference between a flange and a bolt so as to ensure both the tightness and the mechanical strength of the flange joint.
Microwave Pretreatment of Vegetable Materials to Increase the Extraction Yield of Natural Products
Authors: Asofiei Ioana , Calinescu Ioan , Gavrila Adina Ionuta , Ighigeanu Daniel , Martin Diana
Published: February 2020

It was designed and built a laboratory experimental installation (LEI) for the microwave pretreatment of vegetable materials. To study the influence of microwave pretreatment on the total phenolic content (TPC), a conventional extraction of polyphenols from treated and untreated fresh sea buckthorn leaves was performed. For short extraction times, the amount of phenolic compounds was higher for the extracts obtained from treated leaves, but a long pretreatment time (28 s) led to a decrease in TPC. The qualitative analysis showed that the chemical composition is not affected by the microwave pretreatment.
Stress Variation in the Orthodontic Tipping Phenomenon Analysis through the finite element method
Authors: Sita Dan Dragos , Brezeanu Ligia , Bica Cristina , Manuc Dana , Bechir Edwin Sever , Hack Marius , Pacurar Mariana
Published: February 2020

The purpose of the study is to assess through a FEM (Finite Element Method analysis), the behavior of a complex structure (enamel-tooth-alveolar bone-periodontal ligament-pulp), subjected to an external load through an orthodontic bracket-with forces of various intensities and to determine its influence on the entire structure.It is necessary to analyze the way all elements of the structure take over the external action given by the action of an orthodontic appliance through the brackets and the influence on the inner component -the pulp-inside of which there are the nerve endings.
Viscosity of Ternary Blends with Biodiesel, Diesel Fuel and Isopropanol at Different Temperatures
Authors: Nita Irina , Sandu Raluca Georgiana , Osman Sibel , Iulian Olga , Stepan Emil
Published: February 2020

The aim of this study is to report experimental viscosity data of pseudo-ternary biodiesel + diesel fuel + isopropanol system covering the whole composition range and for temperature ranging from 293.15 K to 323.15 K. The accuracy of some equations to estimate the viscosity of this ternary system was evaluated.
Comparative Studies on the Behaviour of Copper in Various Electrically Insulating Fluids
Authors: Lingvay Iosif , Oprina Gabriela , Apostol Emilia Simona , Lipcinski Daniel , Patru Ion , Marinescu Virgil , Luchian Ana Maria , Vaireanu Danut Ionel
Published: February 2020

This paper presents an exhaustive study regarding the behaviour of copper in various insulating fluids when exposed to 1100C for 1000 hours in closed systems, with no access to atmospheric oxygen. Following the analysis carried out, it was found that the variation of oxygen concentration in the investigated oil samples, during the thermal treatment, may be best described using an exponential decrease versus time. Moreover, from the gas chromatography determinations with respect to the evolution of the CO and CO2 content in the oils during the thermal treatment one found out that these fit very well the Richards model, which corroborated with all the other analysis confirms the fact that the copper films undergo consistent morphological changes only when exposed to mineral oils, so that it is of paramount importance that, taking into account this aggressive character, the equipment placed in direct contact with these oils should be carefully inspected on a periodical basis. This behaviour is thought to be a direct consequence of the sulphur compounds contents for these oils, the secondary oxidation products of these compounds increasing their corrosive aggressiveness.
The Clinical Implications of Carbon Dioxide Increased Level in Arterial Blood Related to Severe Exacerbations of Chronic Obstructive Pulmonary Disease
Authors: Jimborean Gabriela , Arghir Oana Cristina , Cambrea Simona Claudia , Dantes Elena , Socaci Adriana , Otelea Marina Ruxandra , Bechir Edwin Sever , Ianosi Edith Simona
Published: February 2020

In the evolution of patients with chronic obstructive pulmonary disease (COPD), exacerbations occur, especially, in severe stages, determining aggravated respiratory failure and decreased survival. In order to evaluate the implications of COPD exacerbations in patients with second type of chronic respiratory failure and hypercapnic encephalopathy, a prospective observational study was done among 195 COPD in patients of Targu Mures Clinical County Hospital, Romania. Inclusion criteria consisted in severe exacerbations of COPD, complicated by hypercapnia, defined by an increased level of arterial blood gas carbon dioxide (PaCO2) �45 mmHg, suggestive for the second type of respiratory failure. The increased values of PaCO2 ranged between 45 and 112 mmHg among 95 patients. The prevalence of hypercapnia in COPD patients, admitted in hospital for severe exacerbations, was high (n=91/195; 46.66%). The majority of COPD patients (93.4%) were initially hospitalized in the intensive care unit (ICU) department because of hypercapnic encephalopathy. The mortality rate was higher among patients with endotracheal tube insertion than in patients treated by noninvasive mechanical ventilation. High levels of hypercapnia, conscience disorders and respiratory acidosis may be considered factors of severity in COPD exacerbation.
Volume Analysis a Novel Tool to Determine Mandibular Cyst Dimensions Using CBCT Technique
Authors: Pintiliciuc Serban Veronica , Mitrea Mihaela , Sindilar Allia , Crauciuc Dragos Valentin , Niculescu Simona , Lupusoru Raoul Vasile , Hurjui Loredana Liliana
Published: February 2020

To evaluate a method of creating three-dimensional representations of mandibular cysts on the cone beam computed tomography (CBCT) data and the data obtained following the evaluation according to Archimede�s principle. A total of 10 mandible with different bone defects miming cysts took part in this study. CBCT scans were obtained from all mandibles and saved in the Digital Imaging and Communications in Medicine (DICOM) format. Data were analysed by two observers: a general dentist and a maxillofacial surgeon. The accuracy of the two methods in assessing cyst volume was compared. There are no major differences between the analysis performed on CBCT data and the real volume of the simulated cystic lesions. Also, there were found differences between the observers. Our results demonstrated the rehabilitee of CBCT scans and volume evaluation of the bone defects. In addition, this study may improve surgical planning and outcomes by knowing the exact volume of grafting material needed prior to the surgical intervention.