bluuebunny/crossref_metadata_2025 huggingface dataset:
Hyers-Ulam-Rassias stability of some perturbed nonlinear second order ordinary differential equations
Authors: Fakunle Ilesanmi , Arawomo Peter Olutola
Published: September 2023

In this paper we investigate the Hyers-Ulam-Rassias stability of a perturbed nonlinear second order ordinary differential equation using Gronwall-Bellman-Bihari type integral inequalities. Further, the paper also investigates the Hyers-Ulam-Rassias stability of four different cases of a perturbed nonlinear second order differential equation.
Personas desaparecidas, búsqueda e identificación. Reflexiones desde la antropología forense en el contexto mexicano
Authors: Rodríguez Carrillo Abel , Hernández-Flores Rocío , Rangel Estrada Diego Antonio , Serrano Sánchez Carlos
Published: September 2023

El desarrollo de la antropología forense en México se encuentra relacionada íntimamente con el contexto de violencia exacerbada, manifiesta en distintas regiones de nuestro país desde la década de los años sesenta del siglo XX hasta la actualidad. Con un especial énfasis en dos guerras, donde el propio Estado mexicano dirigió sus huestes contra su propia población, en este sentido, hablamos de “la guerra sucia” y de la “guerra contra el narco” como dos episodios que favorecieron crímenes de lesa humanidad como lo fue la desaparición forzada y, asimismo, la desaparición por particulares; acaecidas en temporalidades que establecen una  relación intrínseca con el desarrollo y aplicación de la antropología forense en cuestiones de seguridad nacional.
Las alteraciones de tierra de un cementerio tamaulipeco entre 2002 y 2019
Authors: Escorcia-Hernández Lilia
Published: September 2023

La desaparición de personas en México asciende a cifras alarmantes, más de 100 mil individuos entre 1960 y 2022, aunque la mayoría aconteció a partir de 2006.
En el 2014, se incrementó la creación de colectivos de familiares de estas víctimas para iniciar procesos de búsqueda, algunas veces por su propia cuenta, otras más acompañando a las autoridades de los distintos niveles de gobierno y en contadas ocasiones con el acompañamiento de antropólogos solidarios, para orientar con temas relacionados con la búsqueda y la identificación. Sin embargo, los resultados continúan siendo pobres y mayoritariamente nulos.
La complejidad del fenómeno obliga a plantearse hipótesis diversas sobre el paradero de los desaparecidos y la utilidad de algunos métodos y técnicas empleados por las disciplinas antropológicas en estos contextos.
El objetivo de esta investigación es mostrar la sistematización de las alteraciones observadas en el suelo del cementerio privado Jardín de los Ángeles, ubicado en Nuevo Laredo, Tamaulipas, durante el periodo comprendido entre los años 2002 y 2019, por medio de la teledetección, debido a que estas podrían contener fosas comunes con restos humanos de individuos no identificados. Los resultados serán de utilidad para los colectivos de búsqueda y para las autoridades correspondientes de llevarla a cabo.
Competencias específicas de la Organización Mundial de Sanidad Animal (OMSA) fundamentales, que requiere el egresado de Medicina Veterinaria y Zootecnia
Authors: Rochin Berumen Fabiola Lydie , Rodríguez Frausto Heriberto , Ruiz Fernández Eduardo de Jesús
Published: September 2023

La Organización Mundial de Sanidad Animal (OMSA) es una organización intergubernamental encargada de regular la sanidad animal en el mundo. Se contemplan áreas como la epidemiología, enfermedades transfronterizas de los animales, zoonosis, enfermedades emergentes y remergentes, programas de prevención y control de enfermedades dentro de los elementos centrales desde los cuales se construirán las competencias de las profesiones que estén alrededor de ese contexto. La educación veterinaria está comprometida en revisar e incluir en su plan de estudios las competencias específicas de la OMSA. En la Universidad Autónoma de Zacatecas se estableció la metodología de análisis y debate sobre las competencias que el veterinario debe poseer con base en la información científica relativa a la salud animal conjuntamente con experiencia docente existente y preservando el enfoque propuesto por la OMSA. El trabajo supervisado por expertos en educación, acordó acercar el debate hacia un posible consenso con respecto al conocimiento sobre salud animal que debe perfilar al médico veterinario zootecnista. Los resultados emitidos desde las mesas de trabajo de las academias y ejes del plan de estudios concluyeron lo siguiente; las materias que debe contemplar el nuevo plan de estudios son: epidemiología, enfermedades transfronterizas de los animales, zoonosis, enfermedades emergentes y remergentes, programas de prevención y control de enfermedades, higiene de los alimentos, productos de uso veterinario, bienestar animal, legislación veterinaria y ética. Además, procedimientos generales de certificación y habilidades de comunicación fueron otras competencias que surgieron de los consensos, las cuales, contribuyen a la formación integral del médico veterinario zootecnista.
Editorial
Authors: Villatoro Carmen , Vadillo Guadalupe
Published: September 2023

La Revista Mexicana de Bachillerato a Distancia (RMBD) es una publicación electrónica de corte académico y arbitrada. Tiene como propósito divulgar resultados de investigación, teoría y mejores prácticas en bachillerato a distancia. Representa el esfuerzo de las universidades públicas mexicanas que ofrecen Bachillerato a Distancia, agrupadas en la Red de Bachilleratos Universitarios Públicos a Distancia (RED), para proveer un foro que permita compartir resultados de investigación en estos programas y experiencias académicas, tecnológicas y de gestión.
Pablo González Casanova: un compromiso con el acceso universal a la educación
Authors: González Casanova Dolores
Published: September 2023

Con base en vivencias acumuladas a lo largo de toda una vida, este artículo presenta una breve perspectiva sobre la ideología y los logros del Dr. Pablo González Casanova (1922-2023), quien estableció el Sistema Universidad Abierta en la Universidad Nacional Autónoma de México durante su rectorado en 1972. La narrativa entrelaza los aspectos académicos, sociales y humanos, brindando al lector una visión integral de un universitario con un amplio y sólido legado educativo.
Cómo potenciar las habilidades matemáticas con ChatGPT
Authors: Gavira Durón Nora
Published: September 2023

El objetivo del presente trabajo es compartir experiencias sobre cómo ChatGPT puede ser utilizado como una herramienta efectiva para el autoaprendizaje de las matemáticas. La justificación se basa en el hecho de que los estudiantes del Bachillerato a distancia de la UNAM enfrentan desafíos al estudiar matemáticas de manera independiente. En este contexto ChatGPT ofrece una solución al proporcionar asistencia instantánea y accesible en cualquier momento y lugar, con la capacidad de responder preguntas, resolver problemas y brindar explicaciones paso a paso. Por ello,es un aliado en línea en el camino hacia el dominio matemático.
El trabajo colaborativo en los foros en línea, ventanas a la actitud dialógica
Authors: Rodríguez Morales Cleopatra Berenice Areli
Published: September 2023

Se expone la estrategia didáctica implementada en el foro de la racionalidad política, de la asignatura Problemas Filosóficos del bachillerato a distancia de la UNAM (B@UNAM), en la que se retoman los elementos teóricos de Coll, y sus colegas (2007); Díaz Barriga Arceo (2006), Luna Dávila (2013) y Cortina (2000). Además, se describe cómo se concretan en los foros en línea educativos. La importancia de los foros radica en que son el espacio ideal para el desarrollo del trabajo colaborativo y la formación de la actitud dialógica, para que los estudiantes lleguen a acuerdos sociales, que les permitan convertirse en ciudadanos conscientes y participativos. También se valora el papel de las redes sociales, en este caso WhatsApp, el medio para que se diera el debate en tiempo real y lo subieran al foro l. Aunado a lo anterior, se propone la necesidad de implementar botones para que los estudiantes puedan evaluar el trabajo de sus compañeros.
“Alguien en su rincón”: apoyo para padres en el bachillerato en línea
Authors: Hanny Courtney N. , Graham Charles R. , West Richard E.
Published: September 2023

A pesar del creciente interés en la educación en línea K­12, los déficits de participación de los estudiantes y la deserción estudiantil resultante siguen siendo problemas generalizados. El marco de Academic Communities of Engagement (ACE) teoriza que dos grupos apoyan la participación de los estudiantes en línea: la comunidad de apoyo personal y la comunidad de apoyo del curso. Sin embargo, se necesita más evidencia para comprender cómo los miembros de estas comunidades, especialmente los padres, apoyan a los estudiantes en diversos contextos. Utilizando los conocimientos obtenidos de 14 entrevistas semiestructuradas de padres con estudiantes matriculados en la escuela secundaria en línea, este estudio agrega soporte a los roles identificados en el marco ACE al presentar ejemplos reales de padres que apoyan el compromiso afectivo, conductual y cognitivo de sus estudiantes en línea. Los hallazgos también confirman los patrones encontrados en investigaciones anteriores que no se explican con el marco ACE, como la defensa de los padres, la comunicación con los maestros y el autoaprendizaje. Discutimos cómo un enfoque de sistemas para conceptualizar las comunidades ACE permite que el marco capture con mayor precisión las experiencias percibidas de los padres dentro de la comunidad personal de apoyo. También discutimos las implicaciones tanto para los profesionales como para los miembros de las estructuras de apoyo para los estudiantes.
Contextos, logros y perspectivas de los bachilleratos de la Red de Bachilleratos Universitario Públicos a Distancia
Authors: Bonilla Gómez Felicidad , López Martínez Ángel , Hernández Calzada Samuel
Published: September 2023

A partir de entrevistas a los responsables institucionales de los bachilleratos en línea de la RED, se hace un breve análisis de contextos y motivos por los que se crearon estos programas educativos, sus aportaciones y logros más relevantes, así como la visión y perspectivas ante los nuevos retos educativos y tecnológicos. Los hallazgos de los testimonios son muy significativos para conocer las condiciones en que se crearon y se desarrollan dichos programas, así como las innovaciones pedagógicas y tecnológicas que incorporan, con el propósito de mejorar este servicio educativo.
Exploring the Landscape of Computer Networking: An In-Depth Survey
Authors: Safiyanu Adam Musa , Usman Ogah Muhammad , Jibrin Yakubu Awal
Published: September 2023

Abstract: Computer networks have become ubiquitous and now serve as sophisticated systems for sharing digital information. They play a crucial role in analysing, organizing, and distributing vital data for business profitability. Notably, the advent of intranets and internets, which are private networks built on internet technology, is reshaping the business landscape. The rapid adoption of intranets is driven by their ability to enhance information management and dissemination, ensuring that businesses stay competitive. In this article, we introduce fundamental networking concepts
Real Time Sign Language Recognition Using Deep Learning
Authors: Mahimanvitha K. , Arathi Dr. M.
Published: September 2023

Abstract: Sign language is the only tool of communication for the person who is not able to speak and hear anything. Sign language is a boon for verbally challenged people to express their thoughts and emotion. Using this Sign Language Recognition system, the communication gap between people with hearing impairments and the general public can be cleared. In this work, a scheme of sign language recognition has been proposed for identifying the gestures in sign language. With the help of computer vision and neural networks, system can detect the signs and give the respective text as output. The major aim of this work is to build a neural network using a Long Short-Term Memory (LSTM) deep learning model using the video frames which offer the translation of gestures into text. The model is trained with the dataset that is collected using MediaPipe holistic key points from the video of the person which detects the pose, face and hand landmarks. after building the neural network, real-time sign language recognition is performed using OpenCV and a user interface is developed using Streamlit where the gestures are recognized and displayed as text within the highlighted section on the screen
“Es muy sencillo porque, ¿quién no tiene 20 euros o 30?”: Consumismo y economización de la experiencia en las narrativas de hombres que demandan prostitución femenina en España
Authors: Ranea-Triviño Beatriz
Published: September 2023

En las sociedades occidentales desde el fin de la Segunda Guerra Mundial el consumo ocupa un lugar central tanto en la reproducción social como en la configuración de las identidades individuales y colectivas. Desde hace algunas décadas, la Sociología del Consumo ha hecho una gran labor por analizar el significado de las prácticas de consumo y dotar de un espacio propio a los estudios al respecto. Tomando algunas de las aportaciones de los y las sociólogas de esta área, este artículo toma el ejemplo de los hombres que demandan prostitución para analizar cómo los marcos de referencia propios de la sociedad de consumo sobrepasan el hecho del consumo de objetos e impregnan otro tipo de prácticas. En la investigación que aquí se presenta se han realizado entrevistas en profundidad a hombres que demandan prostitución y se ha utilizado el análisis del marco, siguiendo la propuesta de Erving Goffman (2006) para identificar y analizar los marcos consumistas y economicistas propios del capitalismo tardío, a través de los cuales estos hombres organizan sus experiencias en prostitución.
Effect of Avocado Leaves Extract on Creatinin and Urea Levels in Rats Induced NaCl and Prednison
Authors: Najwa Hilya U. , Elisa Novi , Puspitaningrum Ika , Anggraeny Ebta N. , Sundoro Aries K.
Published: September 2023

Creatinine and urea are metabolic waste substances excreted by the kidneys. Kidneys excrete metabolic waste substances. Renal dysfunction is associated with the increased level of creatinine and urea in the blood. The ethanolic extract of avocado leaves (Persea americana Mill.) contains flavonoid compounds, alkaloids, tannins, saponins, and steroids which act as antioxidants and antihypertensive. It is known to reduce creatinine and urea levels in the blood. The animal model was divided into five groups: normal control, negative control (CMC - Na 0.5 %), and avocado leaves ethanolic extract group with doses of 75, 150, and 250 mg/kg BW rats. All groups except the normal control group were induced by oral administration of NaCl solution 2 % and prednisone suspension 1.5 mg/kg BW rats for 21 days and following treatment by oral administration for 7 days based on its group. Flavonoid compounds of avocado leave ethanolic extract identified as 5,7-di-OH-dihydroflavonol. Results show Kruskal - Wallis test between groups (p < 0.05) is significantly different. Concluded that administration of avocado leaves ethanol extract at doses of 75, 150, and 250 mg/kg BW rats might reduce creatinine levels, while avocado leaves ethanol extract at a dose of 250 mg/kg BW rats could reduce urea levels.
Antioxidant Activity Test of Ethanolic Extract of Tempuyung Leaves (Sonchus Arvensis L.) Based on Linoleic - Thiocyanic Method
Authors: Suprijono Agus , Sulistiani Dian , Purwadi Sarosa
Published: September 2023

Free radicals chemically have free electrons, free radicals tend to take electrons from other molecules, which then give rise to abnormal compounds. Antioxidants are substances that can delay or prevent free radical oxidation reactions in lipid oxidation. Tempuyung leaves contain flavonoids which can act as antioxidants. This research aims to determine the antioxidant activity of the ethanol extract of tempuyung leaves using the linoleic-thiocyanate method and to determine the total phenolic and total flavonoid content using the Folin-Chiocalteu reagent method. The results showed that the ethanol extract of tempuyung leaf extract had antioxidant activity. Percentage of antioxidant activity of 10 % extract = 82.91 %, 5 % extract = 70.07 %, 1 % extract = 57.70 %, Vitamin E 1 % = 70.2 1%. Total phenolic content of 10% extract = 0.48 %, 5 % extract = 0.25 % and 1 % extract = 0.04 %. The total flavonoid content of the extract is 10 % = 0.14 %, 5 % extract = 0.07 %, and 1 % extract = 0.02 %. Pearson correlation test showed that phenolic and flavonoid compounds greatly influenced the antioxidant activity of the ethanol extract of tempuyung leaves.
Degradation of Natural Rubber as Asphalt Mixes Modifier using UV-Ozone Light
Authors: Ritonga Irene I. C. , Tamrin Tamrin , Marpongahtun Marpongahtun
Published: September 2023

The elastic properties of natural rubber are indispensable in improving the physical properties of asphalt mixtures. However, the long natural rubber molecule chains make it difficult to modify with other polymeric materials, so it needs to be degraded. In this study, the authors succeeded in degrading natural rubber using a combination of UV light and ozone with the addition of an H2O2 initiator; from the FTIR data, it appears that there are peaks indicating vibrations of the C=O and –OH groups indicating that natural rubber chain termination has occurred. The addition of natural rubber to asphalt was carried out with several variations, namely 8; 10; 12; 14; 16 % (to asphalt content), from the results of the softening point and ductility test of the asphalt mixture explained that the addition of 12 % natural rubber was the most optimum mixture. This result explains that efforts to degrade natural rubber using the UV - ozone combination method can increase the optimum insertion of natural rubber into asphalt mixtures by up to 100 % from previous studies.
Morphological Effect on Swelling Behaviour of Carboxymethyl Cellulose–Maleic Acid Hydrogel Modified with Kombucha Bacterial Cellulose
Authors: Siahaan Tanty N. , Basuki Basuki , Siregar Amir H. , Muthawali Dede I.
Published: September 2023

The incorporation of bacterial cellulose from kombucha tea in carboxymethyl cellulose / maleic acid (CMC / MA) hydrogels has been successfully conducted. This study aims to analyze the relationship between the pores on the surface of the hydrogel with their water-absorbing ability. Bacterial cellulose from kombucha (KBC) was confirmed by the spectrum of OH, C-O-C, and C-OH functional groups with FT - IR analysis. Filler KBC was added to CMC / MA hydrogel with variations in the concentration of 2, 4, 6, and 8 % wt. The CMC / MA / KBC hydrogels were characterized by swelling test, degree of crosslinking, FTIR, and SEM. The swelling results showed that hydrogels with 2 % KBC produced the best water absorbing ability up to 172 %, water absorption decreased with the increase of KBC concentrations. Furthermore, SEM image results showed that the addition of KBC affects the morphological shape and pore size of the hydrogel. Meanwhile, FTIR analysis showed that there were no major changes in the functional groups of hydrogels.
IMPACT OF INTRODUCING PROMPT ON PERMANENT BRACHIAL PLEXUS INJURY & TEARS °III/IV IN SHOULDER DYSTOCIA: THE HANOVER COHORT STUDY
Authors: Papageorgiou Spyridon , Brodowski Lars , Lewinski Halina , Bohnhorst Bettina , Flentje Markus , Kaisenberg Constantin von
Published: September 2023

Objective: to test the hypothesis that PROMPT reduces permanent
brachial plexus palsy and perinatal tears. Design: prospective
/ retrospective cohort study. Setting: Hanover Medical School,
Germany. Population / Sample: a self-selected population.
Methods: training period November 9 2017
until 31 December 2019, control January 1
2004 until November 8 2017.
Main outcome measures: shoulder dystocia, non-permanent and
permanent brachial plexus injuries (BPI), perineal tears III°/ IV°,
manual manoeuvres, and asphyxia. Results: there was a total of
22,640 births, shoulder dystocia increased from 48/18.031
(0.27%) to 23/4.609 (0.50%) (p=0.017), OR 1.88, 95%-CI [1.14;
3.09] whereas BPIs decreased from 7/48 (14.6%) to 1/23
(4.3%) (p=0.261). There was 1/7 (14.2%) of permanent BPI before and
0/1 (0%) case after. Perinatal asphyxia increased from 3/48
(6.3%) to 4/23 (17.4%) (p=0.23). However, adverse outcomes after one
year were zero. McRoberts’ increased from 37/48 (77.1%) to
23/23 (100%) (p=0.013), OR 1.62, 95%-CI [1,33; 1,98] and
internal rotation manoeuvres and manual extraction of
the posterior arm from 6/48 (12.5%) to 5/23 (21.7%)
(p=0.319). Episiotomies decreased from 5.267/18.031 (29.2%) to
836/4.609 (18.1%) (p<0.001) OR 0.54, 95 %-CI [0.49,
0.58], whereas perineal tears III°/IV° associated with
shoulder dystocia increased from 1/48 (2.1%) to 1/23 (4.8%),
(p=0.546). Vaginal operative deliveries remained constant
(6.5% vs 7%). Conclusions: PROMPT significantly improves the
management of shoulder dystocia and decreases permanent brachial plexus
injuries, but not perinatal tears III°/IV°.
FPGA Implementation of Embedded Floating-Point Core with Microarchitectural Support
Authors: Pitchai Saravanan , Pitchai Senthil
Published: September 2023

Floating point arithmetic is a tedious implementation in General Purpose
Processors (GPP) and Application Specific Integrated Circuit (ASIC).
ASICs don’t afford the modifications of instruction and algorithms in
floating point applications. GPP takes over the floating computations in
a separate circuit called a Floating Point Unit (FPU), it makes the FPU
consume more power and chip area. This paper presents the FPU which
incorporates its hardware circuitry for microarchitectural configuration
in FPGA. The proposed FPU provides the RAM blocks for storing the
instructions and data alongside floating point arithmetic circuits.
Compared to conventional implementation, Fused Multiply-Add (FMA)
instruction is implemented with a minimum adder, multiplier, and
shifters resources. An instruction stored in RAM selects and controls
the floating point operations such as addition, subtraction,
multiplication, and Multiply Accumulate (MAC) operations. Pipelined FPU
is implemented as a simple microarchitecture in Stratix III FPGA at the
maximum operating frequency of 463 MHz; proposed FPU shares some hard
floating point circuits in adder multiplier data paths.
Flat Silk Cocoon-Based Wearable Flexible Piezoresistive Sensor and its Performance
Authors: Liu Zulan , Cai Mengyao , Jia Rui , Xu Xiang , Xu Mengting , Cheng Guotao , Cheng Lang , Dai Fangyin
Published: September 2023

Flexible sensors is becoming the focus of research due to its very vital
for intelligent products, real-time data monitoring and recording. The
flat silk cocoon (FSC), as a special form of cocoon, has all the
advantages of silk, which is an excellent biomass carbon-based material
and a good choice for preparing flexible sensors. In this work, a
flexible piezoresistive sensor was successfully prepared by
encapsulating the carbonized flat silk cocoons (CFSC) using an elastic
matrix polydimethylsiloxane (PDMS). The sensing performance of the
material is -0.01 kPa-1. And the monitoring range can reach 680.57 kPa.
It is proved that the sensor can detect human motion and has excellent
durability (>2000 cycles). In addition, the sensor array
for keyboard based on CFSC was explored. The sensor has low production
cost, simple preparation process, sustainable and environmentally
friendly, which might be expected to have potential applications in
wearable devices and human computer interaction.
Patterns of potential cross-species transmission in planktonic multihost-multiparasite communities
Authors: McIntire Kristina , Gowler Camden , Rogalski Mary , Shaw Clara , Hunsberger Katherine , Eisenberg Marisa , Duffy Meghan
Published: September 2023

Most parasite species infect multiple host species, and reciprocally,
most hosts are infected by multiple parasites. This leads to complex
webs of interactions that influence disease within the community, making
it challenging to understand and predict disease spread within the
community and epidemics. Here, we used network approaches to analyze a
multi-year time series dataset that includes eight zooplankton host
species (in the Daphnia and Ceriodaphnia genera) and seven microparasite
species to examine patterns of cross-species transmission. These
analyses suggest that parasite species varied in their ability to infect
multiple host species and in which host species they most commonly
infected. Three parasites (the bacteria Pasteuria ramosa and
Spirobacillus cienkowskii and the oomycete Blastulidium paedophthorum)
showed signatures of relatively high cross species transmission, while
the others seemed more restricted. Even for the three common multihost
parasites, our approach also revealed differences in patterns of
potential cross species transmission. For P. ramosa, two host species,
Daphnia dentifera and D. retrocurva, seem particularly likely to
transmit across species; in contrast, for S. cienkowskii, no host
species stands out as particularly important for cross species
transmission. Additionally, these patterns matched those describing
epidemic size, suggesting that infected host density may drive
cross-species transmission. These results are based on observations of
patterns of infection in natural communities, and therefore we cannot
draw definitive conclusions about interspecific transmission in lakes.
However, some of the patterns are supported by additional lines of
evidence, and others point to interesting avenues for future research.
Together, these findings provide additional evidence that network
approaches can provide valuable insights into patterns of transmission
in complex multihost-multiparasite communities in nature.
Identification of small-molecule antagonists targeting the Growth Hormone Releasing Hormone Receptor (GHRHR)
Authors: Matsoukas Minos-Timotheos , Radomsky Tarryn , Panagiotopoulos Vasilis , Preez Robin du , Tsianakas Konstantinos , Papadourakis Michail , Millar Robert , Anderson Ross , Spyroulias Georgios , Newton Claire
Published: September 2023

Background and Purpose: Growth hormone-releasing hormone (GHRH), a
44-residue neuropeptide produced in the hypothalamus, stimulates the
synthesis and release of pituitary growth hormone via binding to its
cognate receptor, the growth hormone-releasing hormone receptor (GHRHR).
The GHRHR belongs to Class B1 of G protein-coupled receptors (GPCRs).
Class B1 GPCR peptides have been proposed to bind in a two-step model,
where firstly the C-terminal region of the peptide interacts with the
extracellular domain of the receptor and subsequently, the N-terminus
interacts with the seven transmembrane domain of the receptor, resulting
in activation. No non-peptide compounds targeting the GHRHR have been
identified, despite observations indicating that it may be an effective
therapeutic target due to overexpression in several disorders including
prostate, breast, pancreatic and ovarian cancer, and peptide antagonists
displaying promising results in many cancer models. Experimental
Approach: We have utilized several computational tools to target the
GHRHR and identify potential small-molecule compounds directed at this
receptor. These compounds were validated in vitro using a cAMP ELISA to
measure activity at the GHRHR. Key Results: In vitro results suggest
that several of the novel small-molecule compounds could inhibit
GHRH-induced cAMP accumulation. Preliminary analysis of the
specificity/selectivity of one of the most effective hit compounds
indicated that the effect was via antagonism of the GHRHR. Conclusion
and Implications: We therefore report the first non-peptide antagonists
of GHRHR and propose a structural basis for antagonism, which may assist
in the future design of lead GHRHR compounds for treating disorders
attributed to dysregulated/aberrant GHRHR signalling.
Exploring genetic variability and population dynamics for mutant mungbean [Vigna radiata (l.) R. Wilczek] lines: Insights from augmented block design
Authors: Rahevar Parthsinh , Cahuhan RM , Patel Pravin , Patel M.P. , Solanki SD , Viradiya YA
Published: September 2023

The current evaluation was initiated to assess mungbean mutant lines for
yield and their attributes in the M3 generation using an augmented block
design. One thousand two hundred mutated mungbean lines were selected
from the γ (Gamma) irradiated (400 to 700 Gy) population and distributed
into twenty-one different blocks, along with three popular controls. To
evaluate per se performance, variance and population dynamics the
observations on days to flowering, days to maturity, plant height (cm),
number of clusters per plant, number of pods per plant, pod length (cm),
protein percentage, seed index, and seed yield (g) were noted and
analysed. All the lines under consideration showed highly significant
variations for all the evaluated variables, except for days to
flowering. Seventy nine mutant lines were found to have significantly
better yield attributes and are currently being evaluated under station
trial. Skewness and kurtosis analysis unveiled the presence of gene
interactions, offering opportunities for targeted improvement and
efficacy of gamma rays as a mutagen, facilitating the release of
variability within the population. Future mungbean breeding programmes
will benefit from the successful isolation of mutant plants with yield
enhancing traits, such as up to 20 clusters per plant, 71 pods per
plant, 8.55 cm pod length, 26.69% protein content (5% higher than
parent), and 29 gram seeds per plant. In early selection cycles without
the need for replicated trials, this study demonstrated the
effectiveness of the mutagen and augmented design in crating novel
variations evaluating and identifying superior genotypes with improved
yield potential.
Early radical lung cancer outcome after prompt recovery from COVID-19 infection: A real-world study
Authors: Ge Yong , Ma Ran , Feng Tianci , Sun Teng , Feng Shoujie , Zhang Hao
Published: September 2023

Background: There has been an increase in the number of
patients with lung cancer who had previously contracted SARS-CoV-2 and
currently require surgery. This study was to share the early
postoperative outcomes in patients who underwent radical lung cancer
surgery after early recovery of COVID-19 infection. Methods We
retrospectively collected data for 99 patients who had undergone lung
cancer surgery in our hospital during January 2022 and January 2023
(including the peak of the COVID-19 crisis）. The patients were divided
into two groups according to the inclusion criteria and exclusion
criteria. One of these included individuals with a history of SARS-CoV-2
infection. Perioperative and follow-up data at 30-day and 90-day were
recorded. Results There were no statistical differences between
groups (p > 0.05) in terms of their postoperative
complications or 30-day and 90-day postoperative readmission rates.
However, there were significant differences between groups (p
< 0.05) in terms of their tumor sizes, pathological stages,
total drainage volumes, drainage diversion times, and hospital stays.
Conclusions The results of the present trial suggested that it
is safe to implement radical curative lung cancer surgery in patients
without pulmonary impairment and in the early stages (2–4 weeks) of
recovery from SARS-CoV-2 infection.
Economic risk assessment of AC/DC hybrid distribution network planning
Authors: Esmaeilzadeh Zahra , Falaghi Hamid , Ramezani Maryam
Published: September 2023

The growing use of direct current (DC) load demands and distribution
generations (DGs) has led to changes in the distribution network. Due to
DC and alternating current (AC) loads and generators, switching to an
AC/DC distribution network is an effective solution. In this paper, the
AC/DC distribution network planning problem is discussed. Uncertainties
in the load demand and power generation of renewable sources cause
probabilistic behavior of the distribution network, which leads to risk
in the network. Therefore, the technical risks related to the node
voltage and the line loading constraints dominate the problem. By
modeling the cost of damage due to technical risks, these risks have
become economic risks. Using the conditional value at risk (CVaR)
method, the economic risk assessment of planning has been addressed. In
addition, the modeling of hard and soft constraints for technical
constraints has been discussed. The K-means algorithm has been used to
model the uncertainties in the problem. The goals of planning are:
minimizing planning costs and reducing economic risk. The proposed
mathematical model has been solved in MATLAB and general algebraic
modeling system (GAMS) hybrid space using a non-dominated sorting
genetic algorithm (NSGA-II). Numerical results are presented for a
13-node distribution network.
Scaled Experiment and Observation of the Lightning Discharge Process of Rotary Wind Turbines under Different Electrodes
Authors: Deng Yeqiang , yang qianhui , Fang Chaoying , Wang Yu , Chen Xiaoyue , Wen Xishan , Lan Lei , Wu Qiang , Xu Jun , Chen Shaokang
Published: September 2023

In this study, a discharge test for scaled wind turbine is performed to
examine the lightning discharge characteristics of rotary wind turbines,
and an observation platform is designed. Moreover, the wind turbines are
subjected to discharge simulation with rod and arc electrodes, and
high-speed and single-lens reflex cameras are used to observe the
physical discharge process. Under the rod electrode, the downward leader
is initiated first, and its length occupies a larger proportion of the
discharge gap. The discharge contains multiple stepped leaders. When the
gap distance is less than 4 m, the probability of occurrence of negative
stepped leaders may be smaller. As the gap distance increases, the
number of stepped leaders increases significantly. Under the arc
electrode, the upward leader is initiated first, and its length accounts
for a larger proportion of the discharge gap. With the rotation of the
wind turbine, the upward leader is initiated earlier and develops more
fully. Furthermore, the speed of its development does not differ
significantly. The discharge simulation process under the arc electrode
is similar to natural lightning strikes on wind turbines.
Team-bounded DEA efficiency scores: The case of UEFA Champions League Players
Authors: Ivanovic Luka , Radovanovic Sandro , Savic Gordana , Delibasic Boris , Popovic Milena
Published: September 2023

Measuring the efficiency of a football player is an interesting task. Every player invests time and energy to produce an outcome during the game that can lead to a better score for the team. However, football is a team sport, thus the synergy of the entire team is an invisible factor that influences the outcomes a player produces. In this paper, we introduce a novel efficiency estimation model based on the data envelopment analysis that incorporates the team effect in the efficiency score. To achieve this effect, we presented data envelopment analysis models using a single mathematical model. This allows us to define lower and upper bounds on the team efficiency score. More specifically, we introduce a novel type of assurance region constraint around the team performance such that the efficiency score cannot exceed ? times the average team efficiency score. The results of the proposed mathematical model on the UEFA Champions League 2021/22 season show that efficiency scores can be heavily affected by inefficient teammates. However, if the entire team performed well, the drop in efficiency scores is insignificant.
Comparative cardiovascular effectiveness and safety of SGLT-2 inhibitors, GLP-1 receptor agonists and DPP-4 inhibitors according to frailty in type 2 diabetes
Authors: Kutz Alexander , Kim Dae Hyun , Wexler Deborah J. , Liu Jun , Schneeweiss Sebastian , Glynn Robert J. , Patorno Elisabetta
Published: September 2023

Objective

To evaluate the comparative cardiovascular effectiveness and safety of sodium-glucose-cotransporter-2-inhibitors (SGLT-2i), glucagon-like-peptide-1-receptor-agonists (GLP-1RA) and dipeptidyl-peptidase-4-inhibitors (DPP-4i) in older adults with type 2 diabetes (T2D) across different frailty strata.

Research Design and Methods

We performed three 1:1 propensity-score-matched cohort studies, each stratified by three frailty strata, using data from Medicare beneficiaries (2013-2019) with T2D who initiated SGLT-2i, GLP-1RA, or DPP-4i. In time-to-event analyses, we assessed the primary cardiovascular effectiveness composite outcome of acute myocardial infarction, ischemic stroke, hospitalization for heart failure and all-cause mortality. The primary safety outcome was a composite of severe adverse events that have been linked to SGLT-2i or GLP-1RA use.

Results

Compared with DPP-4i, the overall HR for the primary effectiveness outcome associated with SGLT-2i (n=120,202 matched pairs) was 0.72 (95% CI, 0.69-0.75), corresponding to an incidence rate difference (IRD) of -13.35 (95% CI, -15.06--11.64). IRD ranged from -6.74 (95% CI, -8.61--4.87) in non-frail to -27.24 (95% CI, -41.64--12.84) in frail people (Pinteraction<0.01). Consistent benefits were observed for GLP-1RA compared with DPP-4i (n=113,864) with an overall HR of 0.74 (95% CI, 0.71-0.77) and an IRD of -15.49 (95% CI, -17.46--13.52). IRD in the lowest frailty stratum was -7.02 (95% CI, -9.23--4.81) and -25.88 (95% CI, -38.30--13.46) in the highest (Pinteraction<0.01). Results for SGLT-2i versus GLP-1RA (n=89,865) were comparable. Severe adverse events were not more frequent with SGLT-2i or GLP-1RA than DPP-4i.

Conclusions

SGLT-2i and GLP-1RA safely improved cardiovascular outcomes and all-cause mortality with largest absolute benefits among frail people.
Analisis Bantuan Sosial, Pendidikan dan Kesehatan di Provinsi Sumatera Barat
Authors: Septina Septina , Yeniwati Yeniwati
Published: September 2023

Poverty is a complex and multidimensional problem so that it becomes a development priority. This study aims to analyze: (1) the effect of prosperous rice (Rastra) on poverty. (2) the effect of the prosperous family program (PKH) on poverty. (3) the effect of education on poverty. (4) the effect of health on poverty in West Sumatra Province. This research is a descriptive study using data from the National Socioeconomic Survey (SUSENAS) conducted by the Central Bureau of Statistics (BPS) in 2017. The population for this study was all households in West Sumatra Province, totaling 2,511 people. This study was analyzed using ordinary least squares (OLS) regression analysis using the STATA MP 14 program. Based on the results of the study it can be concluded that (1) Rastra significantly influences poverty. (2) education significantly affects poverty. (3) health significantly affects poverty. (4) PKH does not statistically significantly affect poverty.
Dampak Pengembangan Pariwisata Terhadap Kemiskinan di Provinsi Sumatera Barat
Authors: Adelia Geby Fanesa , Azhar Zul
Published: September 2023

This study aims to analyze the impact of tourism development on poverty in West Sumatra Province. This type of research is descriptive and associative, using secondary data. This research method uses path analysis. The variables used are Economic Growth (Y1), Poverty (Y2), Tourism (X1), Government spending on infrastructure (X2). The data used is panel data for 19 regencies/cities for the 2016-2021 period, which were obtained from related institutions and agencies. The results of this study indicate that tourism has no influence on poverty through economic growth as a mediating variable. Government infrastructure spending has a positive and significant impact on poverty in West Sumatra Province. Taken together, there is a significant influence between tourism, government spending on infrastructure, and economic growth, on poverty in West Sumatra Province.
Cultural public relations approach to angklung bamboo musical instrument craft workshop activities
Authors: Gustini Leili Kurnia , Hidayat Dasrun , Aulia Ellena Fitri , Karamani Dinar Dina
Published: September 2023

Background: In preserving cultural sustainability, one needed to be done is to maintain cultural resilience. Saung Angklung Udjo (SAU) producing bamboo craft workshop activities in order to do so. The workshop is part of a Public Relations event that is carried out on an ongoing basis. However, there is a need of strategy to have that workshop run optimally. Purpose: This study aimed to determine the design of a public relations event program in the form of a bamboo craft workshop at SAU. Methods: Six informants were involved and determined purposively, including workshop organizers, presenters, and workshop participants. Results: The results of this study show the existence of workshop stages relevant to the IPPAR model (Insight, Program Strategic, Program Implementation, Action, and Reputation). Insight is the initial preparation stage or situation analysis. Program strategy is the planning stage in the form of a program strategy. Program implementation is the implementation stage, and action and reputation is a public assessment as feedback from activities implementation. Conclusion: Public relations events are needed to manage the image and reputation of Angklung’s cultural values. Implications: The results of this study are expected to impact local government policies in managing cultural arts events. The results of this study can also be used as a development of public relations event studies in the context of culture or cultural public relations.
Evaluating social media marketing in Afghanistan’s private Universities
Authors: Safi Abdul Qayoum , Setianti Yanti , Sapi Abdulmanan
Published: September 2023

Background: Social media has become a significant part of our lives today. Students, in particular, use Internet media technologies to access information about their educational environments. Purpose: This study aimed to assess how private institutions in Afghanistan use social media for marketing purposes. Methods: The perspectives and experiences of noteworthy stakeholders in these universities were investigated using a qualitative research design by conducting in-depth interviews to explore the perceptions and experiences of key stakeholders in private universities in Afghanistan. Thematical analysis was used to examine the data gathered. Results: Social media is crucial for attaining marketing objectives and increasing brand recognition. According to the interviews, social media sites like Facebook, Twitter, Instagram, and LinkedIn are valuable tools for promoting higher education programs and interacting with prospective students. The findings also show that Facebook in Afghanistan, is the most widely used social media sites. Conclusion: Social media has become an essential marketing tool for Afghanistan’s private education institutions. Albeit poor and expensive internet access, which have significantly reduced the effectiveness of social media marketing. The importance of institutions in recognizing their target market, creating efficient social media strategies, and allocating funds wisely, are paramount in order to fulfill the goals. Despite these difficulties, participants saw social media as a valuable tool for promoting higher education programs and connecting with prospective students. Implications: Private education institutions in Afghanistan should recognize the significance of social media as an essential marketing tool despite the challenges of poor internet access and high costs and focus on understanding their target market, developing efficient social media strategies, and allocating resources effectively.
Fostering strategic function of public relations corporate - communication in corporate culture practices
Authors: Koswara Aang , Nugraha Aat Ruchiat , Damayanti Trie
Published: September 2023

Background: Public relations and Culture are intertwined. Societal and corporate Culture influences public relations practices. Conversely, the existence of public relations influences organizational cultural practices and societal Culture. Regrettably, the human resource department has a more dominant role in corporate culture practices than the public relations department. It is mainly related to internalizing organizational values, while the public relations department supports the internalization program through internal corporate communication channels. Purpose: This paper examines public relations function in corporate culture practices based on stories and opinions from Indonesian communication practitioners. It focuses on three main research questions, first how and what the impacts of the existence of public relations – corporate communication to the development of corporate Culture; Second, what the functions of public relations are – corporate communication to support the building and changing corporate Culture; and third what factors influence the strategic function of public relations - corporate communication in corporate culture practice. Methods: This study employs qualitative methods through semi-structured interviews with public relations/corporate communication professionals working at different corporations and organizations. Results: Based on thematic analysis, the empirical findings revealed that cascading organizational values is still part of the human resource department’s primary job, while corporate communication is essential to echoing the key message. Determining the appropriate communication channels and corporate language is critical to ease misunderstandings amongst corporate members. Finally, the digital business environment frequently invites hostile situations, and therefore strong leadership and agile organization can preserve business sustainability. Conclusion: The influence of public relations is essential to orchestrate various internal communication channels. The agile organization provides ease of organizational bureaucracy in corporate culture practices. Implications: This initial finding contributes to the field of public relations – corporate communication to provide a balanced perspective from Indonesian practitioners.
Caracterización de esfuerzo muscular del miembro inferior mediante EMG no invasivo
Authors:   Centro de Investigación Ciencia Aplicada y Tecnología  Avanzada, Unidad Querétaro del Instituto Politécnico Nacional, Martínez- Carreño L.A ,   Facultad de Ingenierías - Ingeniería Biomédica, Unidad de Celaya, Vega- López E. M ,   Facultad de Ingenierías - Ingeniería Biomédica, Unidad de Celaya, Samano Flores Y. J ,   Centro de Investigación Ciencia Aplicada y Tecnología  Avanzada, Unidad Querétaro del Instituto Politécnico Nacional, Hernández Zavala A. ,   Centro de Investigación Ciencia Aplicada y Tecnología  Avanzada, Unidad Querétaro del Instituto Politécnico Nacional, Chaparro- Cárdenas S. L. ,   Centro de Investigación Ciencia Aplicada y Tecnología  Avanzada, Unidad Querétaro del Instituto Politécnico Nacional, Jiménez- Garibay A. A. ,   Facultad de Ingenierías - Ingeniería Biomédica, Unidad de Celaya
Published: September 2023

La caracterización de las señales musculares a través de electromiografía (EMG), es un tema el cual se ha investigado por muchos años, debido a la complejidad relacionada por la cantidad de parámetros de la señal. La selección del electrodo (pre-gelado, seco, o sin-contacto), el procedimiento invasivo o no-invasivo, las condiciones del paciente, el diseño electrónico para adquisición y acondicionamiento de la señal, el diseño de la etapa de filtrado, etc., son algunos parámetros que determinan el nivel de acondicionamiento de la señal EMG. Esta investigación está orientada a la caracterización de señales eléctricas musculares, específicamente en el conjunto muscular de corva que conforman los vientres del cuádriceps, a través de electrodos secos superficiales que permitan obtener una señal limpia del conjunto muscular, con un interés en particular en la selección de electrodos y el diseño electrónico para adquisición y acondicionamiento de la señal.