bluuebunny/crossref_metadata_2025 huggingface dataset:
Hemostatis Analyzer-Supported Hemotherapy Algorithm in Cardiac Surgery: Protocol for a Randomized Controlled Monocentric Trial
Authors: Michel Sophie , Piekarski Florian , Fischer Jan-Hendrik , Hettler Vanessa , Adam Elisabeth Hannah , Holzer Lars , Lotz Gösta , Walther Thomas , Zacharowski Kai , Raimann Florian Jürgen
Published: January 2020

Background

Point of care devices for performing targeted coagulation substitution in patients who are bleeding have become increasingly important in recent years. New on the market is the Quantra. It is a device that uses sonorheometry, a sonic estimation of elasticity via resonance, which is a novel ultrasound-based technology that measures viscoelastic properties of whole blood. Several studies have already shown the comparability of the Quantra with devices already established on the market, such as the rotational thromboelastometry (ROTEM) device.

Objective

In contrast to existing studies, this study is the first prospective interventional study using this new system in a cardiac surgical patient cohort. We will investigate the noninferiority between an already existing coagulation algorithm based on the ROTEM/Multiplate system and a new algorithm based on the Quantra system for the treatment of coagulopathic cardiac surgical patients.

Methods

The study is divided into two phases. In an initial observation phase, whole blood samples of 20 patients obtained at three defined time points (prior to surgery, after completion of cardiopulmonary bypass, and on arrival in the intensive care unit) will be analyzed using both the ROTEM/Multiplate and Quantra systems.
The obtained threshold values will be used to develop a novel algorithm for hemotherapy. In a second intervention phase, the new algorithm will be tested for noninferiority against an algorithm used routinely for years in our department.

Results

The main objective of the examination is the cumulative loss of blood within 24 hours after surgery. Statistical calculations based on the literature and in-house data suggest that the new algorithm is not inferior if the difference in cumulative blood loss is <150 mL/24 hours.

Conclusions

Because of the comparability of the Quantra sonorheometry system with the ROTEM measurement methods, the existing hemotherapy treatment algorithm can be adapted to the Quantra device with proof of noninferiority.

Trial Registration

ClinicalTrials.gov NCT03902275; https://clinicaltrials.gov/ct2/show/NCT03902275

International Registered Report Identifier (IRRID)

DERR1-10.2196/17206
DEVELOPMENT AND EVALUATION OF NANOSPONGE LOADED TOPICAL HERBAL GEL OF WRIGHTIA TINCTORIA
Authors: IRIVENTI PADMINI , GUPTA N. VISHAL
Published: January 2020

Objective: Psoriasis is the most common chronic autoimmune disease. The main objective of the present study was to develop Nanosponge (NS) based Topical gels of Wrightia tinctoria extract using cross-linker and polymer by melting method. It is used in treating Psoriasis.

Methods: Phytoconstituents present in the herbal extract were identified by Liquid Chromatography-Mass Spectroscopy (LC-MS) studies. In vitro drug release and Entrapment Efficiency of all NS were determined. The optimized NS were incorporated in the gel to formulate nano topical gel. Evaluation studies like homogenicity, viscosity, spreadability, pH and In vitro studies were carried out for all gel formulations.

Results: The prepared gels were transparent, had good viscosity and spreadability. SEM photographs confirmed that the prepared formulation were roughly spherical and porous in nature. In vitro diffusion studies showed drug release of 92.15% in 24 h.

Conclusion: From this study it can be concluded that constituents responsible for treating psoriasis are present in the obtained extract and prepared NS based topical gel has significant effect in providing sustained drug release.
OPTIMIZATION OF STATISTICALLY DESIGNED ACECLOFENAC FAST DISSOLVING TABLETS EMPLOYING STARCH GLUTAMATE AS A NOVEL SUPERDISINTEGRANT
Authors: KUMAR R. SANTOSH , MUDILI SAHITHI
Published: January 2020

Objective: To optimize aceclofenac fast dissolving tablets employing starch glutamate as novel superdisintegrant by 23factorial design to improve bioavailability and enhance patient compliance.

Methods: Starch glutamate was prepared by the esterification process. Starch glutamate physical and micromeritics properties had been evaluated and the prepared starch glutamate was used as a superdisintegrant for the formulation of the fast dissolving tablets of aceclofenac by direct compression method and optimized by employing 23factorial design. The prepared aceclofenac fast dissolving tablets were evaluated for post compression parameters as well as in vitro and in vivo release characteristics. Optimized formulation stability studies were performed at accelerated conditions for 6 mo as per ICH and WHO guidelines.

Results: The prepared starch glutamate was amorphous, insoluble in aqueous and organic solvents were tested. Fast dissolving tablets of aceclofenac were formulated by employing starch glutamate as a superdisintegrant showed good tablet properties and showed an increased dissolution efficiency of the drug. Among all the formulations (F1 to F8), the formulation F8 containing 5% concentration of starch glutamate, croscarmellose sodium and, crospovidone as a superdisintegrants showed 99.7±0.15% of drug release within 5 min. Whereas the formulation F2 containing 5% concentration of starch glutamate, drug release characters were comparable to the formulation F8. Optimized formulation F2 attained peak plasma concentration within a short period and showed increased relative bioavailability of the drug.

Conclusion: From the physical properties, disintegration time, in vitro dissolution studies and pharmacokinetic studies, it was concluded that fast dissolving tablets of aceclofenac tablets formulated by employing starch glutamate as a superdisintegrant enhanced the dissolution efficiency and improved the bioavailability of the drug as compared to the pure drug and stable.
FORMULATION AND EVALUATION OF FAST DISSOLVING TABLET OF APREPITANT BY USING NATURAL AND SYNTHETIC SUPERDISINTEGRANTS
Authors: BALA RAJNI , SHARMA SHAILESH , IKGPTU
Published: January 2020

Objective: The present study was aimed to formulate fast dissolving tablets (FDTs) of Aprepitant (APT) using natural and synthetic superdisintegrants with the desired onset of action, increased bioavailability by reducing the frequency of dosage and also reduce the first-pass metabolism of the drug.

Methods: In this research, the gum isolated from cordia dichotoma was investigated as super disintegrants in fast dissolving tablets (FDTs). The aprepitant tablets were prepared separately using cordia dichotoma (natural), sodium starch glycolate and croscarmellose sodium (synthetic) as superdisintegrants by direct compression method. The tablets were evaluated for various precompression and post-compression parameters.

Results: The optimized formulation (APT F3) of cordia dichotoma (8%) showed satisfactory physicochemical properties, minimum disintegration time (34 seconds) and highest dissolution rate (86.52%) in 10 min than the other synthetic superdisintegrants. Also, the pharmacokinetic study of the optimized formulation showed effective results as compared with marketed product of aprepitant.

Conclusion: The developed formulation can improve the onset of action as well as improve patient compliance.
IMPLEMENTATION OF QUALITY BY DESIGN (QBD) APPROACH IN FORMULATION AND DEVELOPMENT OF RITONAVIR PELLETS USING EXTRUSION SPHERONIZATION METHOD
Authors: MANDLIK SATISH K. , AGARWAL PAYAL P. , DANDGAVHAL HARSHAL P.
Published: January 2020

Objective: Ritonavir is an antiretroviral drug used for HIV-AIDS treatment. The purpose of this research work was to implement the quality by design (QbD) approach in formulation of ritonavir sustained-release pellets by industrially applied extrusion spheronization technique.

Methods: Pellets were prepared by extrusion spheronization method and evaluated for their physicochemical properties. Initially, on the basis of prior knowledge Quality Target Product Profile (QTTP) element was identified and further Critical Quality Attributes (CQA) elements were defined. Risk assessment (RA) was done by two tools as failure mode and effect analysis (FMEA) and fishbone diagram (Ishikawa plot). Placket Burman design was implemented as a screening design using seven high-risk factors (spheronization speed, spheronization time, extrusion speed, drying method, PVP K 30, cross povidone, and solvent). Optimization study was done by 23 full factorial design with three critical factors as (spheronization speed, extrusion speed and PVP K 30). The in vitro drug release was studied in both gastric and intestinal fluids for 12 h using USP Ι apparatus. Control space was established for the sustained release pellets.

Results: Among all batches obtained in 23 full factorial design, batch R7 was found to be effective with carr’s index value of 5.281, percentage yield of 69.6%, time required to release 50% drug was 8 h and percent drug release after 12 h was found 83.132 %, R7 batch was selected as optimized batch. Statistical analysis showed model terms were significant.

Conclusion: We can conclude that; sustained-release pellets of ritonavir were successfully designed using QbD approach.
PENGARUH UKURAN, KOMPLEKSITAS, PROGRAM INTERNASIONAL, DAN STATUS AKREDITASI TERHADAP PENGUNGKAPAN INTELLECTUAL CAPITAL PADA UNIVERSITAS MUHAMMADIYAH DI INDONESIA
Authors: Aulia Desti , Ulum Ihyaul , Wahyuni Endang Dwi
Published: January 2020

The purpose of this study was to identify the effect of size, complexity, international programs, and accreditation status on the disclosure of intellectual capital at Muhammadiyah universities in Indonesia. This study uses purposive sampling with a sample of 41. The IC component used in this study is the Leitner (2002) framework developed by Ulum (2012) which consists of 46 items. Data analysis using content analysis and WarpPLS 6.0. The results showed that the disclosure of Intellectual Capital at each University was different, in terms of the amount of information disclosed, the size of the Muhammadiyah University had a significant positive effect on the disclosure of intellectual capital, as well as the complexity, international programs, and accreditation status had a significant positive effect on the disclosure of the Muhammadiyah University's 4ICU version 2018.
Hubungan Tingkat Kecemasan Dengan Hemodinamik Pasien Gagal Ginjal Kronik Yang Menjalani Hemodialisa
Authors: Nurlinawati Nurlinawati , Rudini Dini , Yuliana Yuliana
Published: January 2020

Latar Belakang : Pasien hemodialisis seringkali mengalami kecemasan. Kecemasan ini apabila tidak diatasi akan mempengaruhi aspek fisiologis dan hemodinamik yang dikhawatirkan akan menimbulkan komplikasi yaitu dialysis disequilibrium syndrome. Penelitian ini bertujuan untuk mengetahui  hubungan  tingkat  kecemasan  dengan  kondisi  hemodinamik  pasien  gagal  ginjal kronik yang sedang menjalani hemodialisa. Metode : Jenis penelitian kuantitatif dengan menggunakan cross sectional. Sampel dalam penelitian ini berjumlah 57 responden. Analisis univariat menggunakan distribusi frekuensi dan analisis bivariat menggunakan regresi linier sederhana. Hasil : Hasil penelitian didapat tingkat kecemasan hanya berhubungan dengan Mean Arterial Pressure (MAP) sebelum hemodialisis dengan nilai signifikan 0.023 dan sesudah hemodialisis didapatkan nilai signifikan 0.026. Sedangkan nadi dan respirasi rate tidak terdapat hubungan dengan nilai signifikan >0.05. Kesimpulan : Ada hubungan antara tingkat kecemasan dengan Mean Arterial Pressure (MAP) pasien gagal ginjal kronik yang sedang menjalani hemodialisa di ruang Hemodialisa RSUD Raden Mattaher Jambi Tahun 2018.
Sosialisasi Tentang Bahaya Narkotika Di Kalangan Sekolah Dasar di Kecamatan Danau Teluk Kota Jambi
Authors: Arfa Nys
Published: January 2020

Di dalam Undang-Undang Nomor 35 Tahun 2014 Tentang Perlindungan Anak ditegaskan bahwa: “Anak adalah tunas, potensi, dan generasi muda penerus cita-cita perjuangan bangsa, memiliki peran strategis yang mempunyai ciri dan sifat khusus yang menjamin kelangsungan eksistensi bangsa dan negara pada masa depan”. Salah satu permasalahan anak adalah mengenai penyalahgunaan narkotika. Narkotika yang pada awal mula penggunaannya bertujuan untuk memnuhi perkembangan ilmu pengetahuan dan pelayanan kesehatan, kini keberadaannya menjadi ancaman bagi kelangsungan hidup masyarakat khususnya anak karena disalahgunakan oleh pihak yang tidak bertanggungjawab. Hal ini yang menjadi dasar dari tim pengabdian pada masyarakat untuk ikut berperan aktif dalam memberikan pengetahuan dan pemahaman yang tepat tentang Undang-Undang Narkotika yaitu Undang-Undang Nomor 35 Tahun 2009. Dengan tujuan siswa yang mengikuti penyuluhan hukum dan sosialisasi UU Narkotika yang dilakukan oleh Tim Pengabdian Kepada Masyarakat Fakultas Hukum Universitas Jambi di Sekolah Dasar di Kelurahan Tanjung Pasir Kecamatan Danau Teluk Kota Jambi mengetahuinya tentang bahaya narkotika dan bisa memberikan pemahaman dan penyebaran informasi kepada para guru hingga bisa dicegah untuk melakukan hal-hal yang melanggar Undang-Undang Narkotika atau juga mencegah anak didik jadi korban narkotika yang bisa merusak masa depan anak salah satunya.
Motivasi Widyaiswara Dalam Penulisan Karya Tulis Ilmiah Pada Badan Pengembangan Sumber Daya Manusia Provinsi Jambi
Authors: Asnofidal Asnofidal
Published: January 2020

Pembuatan karya tulis ilmiah merupakan bagian dari tugas dan kewajiban bagi widyaiswara, karena mereka berfungsi sebagai pengembang sumber daya manusia aparatur sipil negara. Membuat karya tulis ilmiah memerlukan motivasi yang kuat, karena ia merupakan tugas yang memerlukan konsentrasi penuh. Penelitian ini tentang motivasi widyaiswara Badan Pengembangan Sumber Daya Manusia (BPSDM) Provinsi Jambi untuk membuat karya tulis ilmiah. Data diperoleh melalui Wawancara, Observasi, Focus Group Siscussion (FGD) dan Studi Pustaka. Informan dipilih secara porpusive sampling dan dianalisis dengan metode trianggulasi. Hasil penelitian memperoleh bahwa widyaiswara BPSDM Provinsi Jambi memiliki motivasi instrinsik untuk membuat karya tulis ilmiah yang muncul dari dalam dirinya sendiri, yaitu untuk peningkatan kompetensi diri, karir dan kenaikan pangkat. Selain itu, widyaiswara juga memiliki motivasi ekstrinsik untuk membuat karya tulis ilmiah, yaitu dukungan lingkungan yang nyaman, fasilitas atau sarana dan prasarana yang cukup, dan dukungan kebijakan pimpinan BPSDM Provinsi Jambi dengan berbagai program dan ketersediaan anggaran. Dalam rangka meningkatkan  motivasi widyaiswara BPSDM Provinsi Jambi untuk membuat karya tulis ilmiah perlu disarankan beberapa hal sebagai berikut: pengaturan jadwal widyaiswara untuk mengajar secara struktural,  sehingga setiap tahun widyaiswara dapat menghasilkan karya tulis ilmiah, mengikutserta widyaiswara dalam setiap kegiatan pertemuan ilmiah seperti seminar dan konferensi baik di dalam daerah maupun di luar daerah, menyediakan anggaran penelitian dan pembuatan karya tulis ilmiah, dan sangat penting memasukkan karya tulis ilmiah sebagai beban kinerja widyaiswara yang harus dimuatkan dalam Sasaran Kinerja Pegawai (SKP).
Studi Komparatif Mediasi Antara Peraturan Mahkamah Agung (PERMA) Nomor I Tahun 2008 Dan Peraturan Mahkamah Agung (PERMA) Nomor I Tahun 2016
Authors: Alissa Evalina , Erwita Yerni
Published: January 2020

Mediasi sebagai instrumen penyelesaian sengketa berdasarkan ketentuan Pasal 130 HIR dan Pasal 154 Rbg yang mewajibkan hakim untukterlebih dahulu mendamaikan para pihak yang berperkara sebelum perkaranya diperiksa. Diundangkannya PERMA No. I Tahun 2008 dan diperbaharui dengan PERMA No.ITahun 2016 yang memberikan panduan tentang penjelasan prosedur mediasi bagi para pihak untuk menyatakan perdamaian. Objek masalah hukum dalam penelitian ini adalah menganalisis perbandingan substansi dari dua Peraturan Mahkamah Agung, dan menganalisis efektivitas mediasi sebagai solusi untuk mengurangi akumulasi kasus sehingga mewujudkan proses peradilan yang cepat dan murah. Pendekatan penelitian yang dilakukan adalah statuta dan pendekatan konseptual terhadap materi hukum yang telah dikumpulkan melalui penelitian kepustakaan. Hasil penelitian menunjukkan bahwa ada beberapa pengaturan tentang  mediasi, yang telah mengalami perubahan dalam Peraturan Mahkamah Agung Nomor I Tahun 2016 adalah: (1) kewajiban  untuk memberikan formulir penjelasan hakim ketua majelis tentang mediasi dan formulir pernyataan para pihak tentang penjelasan mediasi yang wajib ditanda tangani para pihak, (2)mempersingkat waktu mediasi, kewajiban para pihak untuk secara langsung menghadiri pertemuan mediasi, (3) adanya niat baik dalam proses mediasi serta konsekuensi hukum jika niat baik ini dilanggar. Implementasi mediasi belum dapat menjadi sarana yang efektif untuk mengurangi akumulasi kasus perdata karena masih banyak kendala, termasuk rendahnya tingkat pemahaman dan kesadaran masyarakat tentang fungsi mediasi. Oleh karena itu, peran aktif hakim yang ditunjuk sebagai mediator untuk memberikan pemahaman dan pengetahuan yang benar tentang manfaat dan fungsi mediasi dalam sistem hukum perdata di Indonesia sehingga peradilan yang cepat dan murah dapat diwujudkan.
The Correlation Between Reading Comprehension Ability and Vocabulary Class IX At SMP N 6 Jambi
Authors: Dewi Kartika
Published: January 2020

The main purpose of this study was to find out whether there is any correlation between Reading Comprehension and vocabulary class IX at SMP N 6 Jambi. The hypotheses of this study are, (1) there is no correlation between reading comprehension and vocabulary (2) there is any correlation between vocabulary mastery and reading comprehension. The problem of this research  study was: is there any correlation between  reading comprehension and vocabulary class IX at SMP N 6 Jambi? The population of this research was 373 students. The sample of this research was 76 students which were taken cluster random sampling from two classes. To conduct this study, qualitative method was used. The data were analyzed by using, Pearson Moment Product Bivariate with SPSS. Based on the findingit was found that the average score reading comprehension test was 56, 5 and the score vocabulary   test was 52, 9 .it means that the students'  reading comprehension   was  fair.  And the students' competency in vocabulary was fair. Based on the finding, it was found that the correlation coefficient obtained is 0.001. It shows that there is no correlation between vocabulary mastery and reading comprehension and vocabulary.
Analisa Perbandingan Tools Ekstaktor Whatsapp Database Crypt12 Menggunakan Metoda Logical Extraction
Authors: Akbar Zulkarnaen , Krisnadi Iwan
Published: January 2020

Dengan lebih dari 1000 juta pengguna aktif berdasarkan survey 2017 perkembangan ini semakin meningkat setiap tahunnya. Perlu diketahui bahwa WhatsApp mempunyai suatu tabel database yang tersimpan secara rasahsia didalam sistem sistem Android yang selalu update secara realtime. Database ini selau dicadangkan secara otomatis melalui fitur autobackup yang tersimpan berbeda dengan database utama. Database hasil backup ini mempunyai format file .crypt12. File crypt12 ini tidak dapat diakses secara sembarang karena telah dienkripsi oleh apliksi ini.Beberapa penelitian telah banyak membahas tentang WhatsApp forensics diperangkat android dengan menggunakan beberapa medode salah satunya adalah metode “logical Extraction” .Dalam melakukan uji coba forensics muncul permasalahan ketika akan dilakukan uji forensics pengguna aplikasi telah menghapus percakapan yang telah dilakukan ini bertujuan untuk menghilangkan jajak dari pengguna WhatsApp. Didalam kasus ini sebenarnya kita dapat melihat percakapan yang telah dihapus dengan melihat data crypt12 dari WhatsApp dengan cara mendeskripsikan data base tersebut. Ada beberapa tools untuk mendeskripsikan file crypt12. Pada penelitian ini akan membandingkan tools untuk mendeskripsikan file data base WhatsApp. Hasil penelitian menghasilkan dalam menganalisa uji forensics tidak lah cukup hanya mengandalkan tools yang dibandingkan akan tetapi harus melihat database hasil deskripsi. File crypt12 (database backup) dan file asli dalam system pada dasarnya mempunyai isi yang sama, akan tetapi terjadi perbadaan dikarenakan dalam proses backup tidak lah update karena WhatsApp hanya akan membackup setian 24 jam sekali.
BIBLIOTERAPIA E LITERATURA INFANTOJUVENIL: UMA PROPOSTA DE HUMANIZAÇÃO DO ESPAÇO HOSPITALAR A PARTIR DA FORMAÇÃO DE LEITORES
Authors: Barros Alexandra Ramos , Goulart João Batista Da Silva , Accorsi Ana Maria Bueno
Published: January 2020

Quando internadas, as crianças e os adolescentes tendem a ver o hospital como um local desconhecido, não familiar, no qual passam por tratamentos e exames muitas vezes dolorosos e associam esta experiência a sentimentos como o medo e a insegurança. Nesse sentido, este artigo pretende sustentar que a proposta da Biblioterapia, conceito o qual corrobora a possibilidade da literatura desempenhar uma função de sublimação catártica na medida em que pode aliviar as tensões e a pressão das emoções, enquanto promoção da formação de leitores através da utilização de literatura infantojuvenil. Ao admitir-se como metodologia a possibilidade de terapia por meio da leitura de textos literários, considerando não apenas a leitura de histórias, mas os comentários adicionais a ela, o leitor/ouvinte valer-se-á de poderosos processos mentais - introjeção, projeção e introspecção -, adquirindo, portanto, valor terapêutico. Destarte, buscaremos a partir de uma vasta pesquisa bibliográfica, a afirmação de respostas às quais permitirão visualizar que a inserção da literatura em um espaço doloroso permite a fabulosa expectativa de que o imaginário possa dialogar com a dor e que os aspectos positivos e de esperança possam ser engendrados nesse contexto.
PERFIL DOS USUÁRIOS E A NECESSIDADE DA GESTÃO PARTICIPATIVA PARA O USO PÚBLICO DA MATA DA BIOLOGIA, VIÇOSA, MG
Authors: Batista Aline Duarte , Batista Aline Duarte , Fernandez Thais Almeida Cardoso , Bontempo Gínia Cezar , Bittencourt Natália Lelis , Silva Ita De Oliveira e
Published: January 2020

Esse trabalho oferece um novo olhar para a Mata da Biologia, maior área verde da regiãourbana de Viçosa-MG. A Mata está situada no Campus da Universidade Federal de Viçosa (UFV) econta com trilhas sem atenção adequada, fragilizando e limitando o uso público, as atividades deextensão, pesquisa e ensino, além de trazer riscos aos visitantes. Para indicar apontamentos para umanova forma de gestão da área, o grupo de extensão “Trilheiros do Sauá” realizou um levantamento eanalisou o perfil e os motivos dos usuários da Mata nos anos de 2014-2015. Tal análise se torna aindamais relevante em consequência do fechamento da Mata da Biologia à comunidade durante a semana,em 2017, em virtude de uso e tráfico de drogas na área. No levantamento foram realizadas 100entrevistas semi-estruturadas, analisadas por meio da estatística descritiva e análise de conteúdo. Aproblemática se destaca ao identificar que a maioria dos usuários da Mata não era vinculado à UFV,ressaltando a importância da mesma para a população local. Lazer, atividades físicas e contemplação danatureza foram os usos mais relatados para a área. Além disso, conflitos foram identificados:insegurança, presença de lixo, uso de drogas, casos de furtos e obscenidade. Essa análise trouxeimportantes subsídios para uma estruturação da gestão da Mata da Biologia. Espera-se que, com essapublicação, a administração da UFV retome a discussão sobre a importância dessa área protegida,possibilitando a gestão participativa e o uso público da mesma.
METODOLOGIAS LÚDICAS NA PREVENÇÃO DA ESQUISTOSSOMOSE E OUTRAS DOENÇAS PARASITÁRIAS EM ESCOLAS PÚBLICAS DA BAHIA – RELATO DE EXPERIÊNCIA
Authors: Pereira Camila
Published: January 2020

No município de Jequié, a esquistossomose é considerada um problema de saúde pública. Nacriança causa um impacto na nutrição, desenvolvimento intelectual e somático. As atividades lúdicaspodem facilitar o processo de ensino-aprendizagem e ainda serem prazerosas, interessantes edesafiantes. Este trabalho faz parte de um projeto de extensão contínuo que se iniciou em 2003 com osobjetivos de ensinar a prevenção das parasitoses em escolas públicas usando atividades lúdicas, e levarinformação sobre a prevenção aos familiares. Para alcançarmos os objetivos, discentes dos cursos deenfermagem, odontologia e biologia da UESB ministraram oficinas educativas, enquanto cursaram adisciplina Parasitologia Humana. Uma série de atividades lúdicas foi aplicada durante as oficinaseducativas. Como procedimento avaliativo utilizou-se: desenhos, massa de modelar, gincanas entre outrosrecursos. Para prestar esclarecimentos aos pais das crianças e adolescentes sobre a prevenção dasparasitoses foram realizadas reuniões nas escolas e visitas domiciliares. Percebeu-se pelos alunos, fatoconfirmado através: das observações diretas, de diálogos em sala de aula, análises de questionários, doconteúdo dos desenhos e massas de modelar, que os principais aspectos a respeito das transmissões eprevenções das parasitoses foram bem compreendidos pela maioria dos escolares. Foram realizadosexames coprológicos dos escolares. Neste estudo, destacou-se a elevada frequência da esquistossomose(22%), seguida da ascaridíase (14,7%), tricuríase (11,8%). Nos protozoários, o índice encontrado foide 10,2% para amebíase e 8,0% para giardíase. Os parasitados foram encaminhados ao atendimentomédico na própria escola ou orientados a procurarem um posto de saúde para o tratamento específico
Mutu Minyak Jelantah Dengan Adsorben Biji Salak (Salacca zalacca (Gaertn.)Voss) menggunakan Parameter Bilangan Peroksida dan Asam Lemak Bebas
Authors: Ihwan Ihwan , Fadlia Fadlia , Anam Syariful
Published: January 2020

Quality of used cooking oil with snake fruit (Salacca zalacca (Gaertn.) Voss) seed adsorbent  has been conducted. This study aims to determine the ability of snake fruit seed in reducing peroxide value and free fatty acids in used cooking oil which can improve the quality and extend usage lifespan of the used cooking oil. The oil sampled in this study was packaged cooking oil which is usually used to fry food untill 7th frying. The oil was then neutralized using snake fruit activated charcoal. The test refers to the Indonesian National Standard (SNI) 7709: 2012 as the quality requirements of cooking oil. The results showed that snake fruit activated charcoal can reduce peroxide value as much as 56.18% and free fatty acid 76.04% in the used cooking oil.
Formulasi dan Analisis Nilai Gizi Bakso Kotak dari Jamur Tiram Putih (Pleurotus Ostreatus)
Authors: Lamadjido Sri Rahayu , Umrah Umrah , Jamaluddin Jamaluddin
Published: January 2020

Meatballs are processed meat products that very popular in Indonesia. Making meatballs is not just using animal material only, but also can be used plant materials such as oyster mushrooms. The meatballs can be made in various forms, such as a round shape or a box shape. This study aims to determine the nutrient content (moisture, ash, fat, protein, and carbohydrates) in several formula meatballs box of oyster mushroom (Pleurotus ostreatus) and find the best formula on the meatballs box oyster mushrooms, the nutrients (fat, protein, and carbohydrates), as well as the ash and moisture content. The study was designed using completely randomized design (CRD), which consists of six treatments and two replications. Parameters measured were as hedonic organoleptic include color, aroma, flavor and texture, using 15 panelists and nutrient analysis includes the levels of fat, protein, carbohydrate, ash content and water content. The results showed that the formulation of meatballs box, panelists preferred the formula II from another formula with a value of 3.06 based on color, aroma, flavor, and texture. The results of nutritional analysis were fat content of 0.77, protein content of 16:28 value, carbohydrate content of 31.4, ash content of 1:46 and water content of 9.44.
Pengaruh Metode Ekstraksi Terhadap Rendemen Dan Kadar Fenolik Ekstrak Tanaman Kayu Beta-Beta (Lunasia amara Blanco)
Authors: Hasnaeni Hasnaeni , Usman Suriati , Wisdawati Wisdawati
Published: January 2020

Lunasia amara Blanco bark belonging to the family Rutaceae. The research aimed to determine the effect of extraction method on yield value and phenolic content of bark extract of Lunasia amara Blanco by UV-Vis spectrophotometry. Sample was extracted by maceration, reflux, and soxhlet using methanol 70%. The extraction by maceration obtained the yield value of methanol extract of 2,352%; the reflux method of 1,611%; and the soxhlet method of 0,960%. Then the chemical content was identified by the addition of FeCl3 reagent and a blackish green color was formed positively indicating phenolic content. Afterward, phenolic identification was conducted by TLC with eluent n-hexane: ethyl acetate (2:8) containing phenolic because the Rf value was the same as the galic acid standard. The results showed that the extraction method producing the highest yield of bark extract of Lunasia amara Blanco was maceration. The phenolic content obtained by maceration was 66,548 mgGAE/g extract with 6.6548% GAE; the reflux was 73.645 mgGAE/g extract with 7.3645% GAE; and the soxhlet was 74.806 mgGAE/g extract with 7.4806% GAE.
Aktivitas Antioksidan Ekstrak Etanol Buah, Daun, Batang Dan Rimpang Pada Tanaman Wualae (Etlingera Elatior (Jack) R.M Smith)
Authors: Jabbar Asriullah , Wahyuni Wahyuni , Malaka Muh Hajrul , Apriliani Apriliani
Published: January 2020

Wualae (Etlingera elatior (Jack) R.M Smith) is one of the plants in the Zingiberaceae family, widely used in medicine ranging from rhizomes, fruits, and flowers. Empirically Wualae are usually used by people for treating skin diseases, flavoring food, a natural soap, and in Southeast Sulawesi, it is used to treat typhoid fever. This study aims to examine the antioxidant activity of Wualae (Etlingera elatior) plant. The plant extracts were extracted by maceration method, antioxidant activity test was performed by 2,2-Diphenyl-1-picrylhydrazyl (DPPH) method. The results showed that ethanol extracts of fruits, leaves, stems and rhizomes of Wualae (Etlingera elatior) has the potential antioxidant activity with the IC50 values of 72.518 mg/L, 99.890 mg/L, 52.345 mg/L and 58.638 mg/L, respectively. and Vitamin C has IC50 value of 3,787 mg/L.
Sustainability Balanced Scorecard: an Alternative to Apply Legitimacy Theory
Authors: Pertiwi Imanda Firmantyas Putri , Hidayati Isnaini Nur , Retno Meilani Sayekti Endah , Rahmayati Anim
Published: January 2020

Purposes. Sustainability Balanced Scorecard (SBSC) is the development of balanced scorecard as a comprehensive company performance appraisal method, which the assessment focus on financial perspective, customer, internal business processes, growth and learning as well as the social and environmental perspective as an effort of sustainability. This sustainability effort is in line with the legitimacy theory, which states that the company should be run in accordance with the prevailing norms of the place where the company is located. Madukismo Sugar Company (PG. Madukismo) is a company that has potential environmental destruction is the subject of this research. This research is intended to provide an overview of PG Madukismo's performance evaluation using the SBSC method, whether it is able to explain the legitimacy theory.Method. The case study with a descriptive qualitative method by triangulation system becomes a method of this research development.Findings. Outlined, the performance of PG Madukismo shows good results, the financial perspective shows some improvement, profit has increased, as well as efficiency. The customer's perspective also shows satisfactory performance, the high level of customer retention and the minimum level of complaints is enough to explain. The internal business process perspective results are also satisfactory, innovation on production, sales and after-sales processes are considered good. A less encouraging perspective is the perspective of growth and learning, even though employee retention is good but the amount of employee training actually shows a downward trend. Last but not least, is a social and environmental perspective. The results obtained were quite surprising, although in 2016 the news about Madukismo waste management was less pleasant, in 2018 Madukismo was able to improve its waste management and get a positive response from surrounding communities who said that the stench from Madukismo waste continued to decrease.Implication. This research gives insight and detail of how to assess a company using five perspectives of SBSC to prove that legitimacy theory can be applied and bringing the hope of sustainable business.Keyword: Sustainability Balanced Scorecard, green accounting, social and environmental, PG.Madukismo
Columnar metaplasia and Barrett’s esophagus: morphological heterogeneity and immunohistochemical phenotype
Authors: Mikhaleva L.M. , Voytkovskaya K.S. , Fedorov E.D. , Gracheva N.A. , Birukov A.E. , Shidiy-Zakrua A.V. , Guschin M.Yu.
Published: January 2020

Barrett’s esophagus (BE) is a pathologically confirmed intestinal metaplasia (CM) of the distal esophagus. BE is recognized as a potential complication of gastroesophageal reflux disease (GERD) and a premalignant condition with a high risk of neoplastic progression. The aim of this study was to compare the morphology of biopsied BE segments and CM segments extending < 1 cm and > 1 cm above the gastroesophageal junction (GEJ), as well as to perform the immunohistochemical analysis of biopsies with BE and CM > 1 cm above GEJ with or without dysplasia. The study recruited 92 patients with GERD: 42 patients with BE, 24 patients with CM > 1 cm above GEJ (С0М1.5–С13M14) and 26 patients with CM < 1 cm above GEJ (С0М0.3–0.8). Comparative analysis of tissue morphology revealed an association between the reactive changes in the epithelium and the severity of esophagitis in all groups. Reactive changes were detected significantly more often in BE segments than in CM segments > 1 cm (Mann-Whitney U, p < 0.05). Eight patients with BE (19.05%) were found to have low-grade dysplasia. One patient with CM > 1 cm above GEJ (4.2%) had high-grade dysplasia with cardiac-type metaplasia and immunohistochemical features of submorphological enteralization. Immunohistochemical testing for the intestinal and gastric markers of cell differentiation revealed the signs of submorphological enteralisation in all esophageal specimens with cardiac and fundic type metaplasia and in the specimens with BE in the areas lacking goblet cells.
Motivasi Kepesertaan Mandiri BPJS di Era Universal Health Coverage Jaminan Kesehatan Nasional
Authors: Dahliana Anita
Published: January 2020

Abstract. This research was conducted to determine the motivation of BPJS Health participants as independent participants. In this study, researchers used a motivational theory developed by Clayton Alderfer with three indicators namely Existence, Relatedness and Growth with a descriptive quantitative research approach with non-random sampling using a purposive method using conditions in selecting respondents ie respondents were outpatients in Specialist Poly Wiyung Hospital, Surabaya. The selected respondents were 43 people.The results of this study were the discovery of community motivation as independent health insurance participants.

Abstrak. Penelitian ini dilakukan untuk mengetahui motivasi peserta BPJS Kesehatan sebagai peserta mandiri. Pada penelitian ini, peneliti menggunakan teori motivasi yang dikembangkan oleh Clayton Alderfer dengan tiga indikator yaitu Existence, Relatedness dan Growth dengan pendekatan penelitian kuantitatif deskriptif. Teknik pengambilan sampel non-random menggunakan cara purposive, yakni pemilihan responden menggunakan syarat tertentu (responden adalah pasien rawat jalan di Poli Spesialis RS Wiyung Surabaya). Responden yang dipilih berjumlah 43 orang. Hasil penelitian ini menunjukkan adanya motivasi masyarakat yang menjadi peserta mandiri jaminan kesehatan.
Profile of oral manifestations, oral hygiene, and nutritional status in pregnant women
Authors: Hidayat Wahyu , Pribadi Indra Mustika Setia , Zakiawati Dewi , Suwargiani Anne Agustina
Published: January 2020

Introduction: The pregnancy condition leads to few changes in women’s bodies, such as hormonal, physiological, and diet. These changes also manifest in dental and oral health. Hormonal changes affect the susceptibility of oral mucosal tissue, whereas emotional and dietary changes alter the pattern of dietary intake, dental cleaning, oral hygiene, and nutritional status. The purpose of this study was to discover the profile of oral manifestations, oral hygiene, and nutritional status in pregnant women. Methods: The population of the study was the pregnant women who visited the Garuda Community Health Centre in Bandung. Subjects were pregnant women aged 17-43 years old. The samples must meet the inclusion criteria of good health status, and the exclusion criteria were no systemic abnormalities, and not currently under long-term antibiotic therapy. The research design was a cross-sectional observation. Indicators measured in this survey were the profiles of oral manifestations, oral hygiene status which assessed using OHI-S, and nutritional status of pregnant women using haemoglobin (Hb) and Body Mass Index (BMI) level. Results: Oral manifestations found in pregnant women were tongue disorders and ulceration, with the coated tongue as the most frequently detected manifestation, and the least found was recurrent aphthous stomatitis, whereas the oral hygiene of pregnant women was categorised as good in the 1st and 2nd-trimester of pregnancy. However, it was found to be moderate in the 3rd trimester. In respect of the Hb level, the nutritional status of the pregnant women was averagely good. By contrast, the BMI score revealed that pregnant women was found of having overweight during the 2nd and 3rd trimester. Conclusion: The most frequently found oral manifestation in pregnant women is coated tongue, while the oral hygiene is categorised as good on the first two trimesters, and the nutritional status in the last two trimesters is considered as overweight.Keywords: Oral manifestation, oral hygiene, nutritional status.
A Biblioteca José de Alencar: sua história, memória e patrimônio
Authors: Borges Cila Verginia da Silva , Viegas Solange Ribeiro , Silva Rosângela Coutinho da
Published: January 2020

A Biblioteca José de Alencar, idealizada e inaugurada pelo Professor Afrânio Coutinho em 09 de abril de 1969, é fonte de história, patrimônio, memória, pesquisa e leitura, referência na América Latina por seu acervo riquíssimo na área de Linguística, Filologia e Literatura. Os exemplares raros, as primeiras edições, as obras autografadas e os livros com edições esgotadas foram reunidos no Museu de Língua e Literatura. A inauguração da BJA ocorreu com uma exposição de obras selecionadas, das coleções da Biblioteca da antiga Faculdade Nacional de Filosofia, da Biblioteca Central da Universidade e de coleções particulares de maior importância bibliográfica como: Coleção Camoniana, Coleção Eciana, Coleção Adir Guimarães, Coleção Shakespeariana, Coleção Bastos Tigre. Em 06 de março de 1985, a Biblioteca José de Alencar foi reinaugurada no campus universitário da Ilha do Fundão. Em 1994, foram adquiridas as coleções dos professores Celso Cunha e Afrânio Coutinho, esta especializada em Literatura e Crítica Literária. De 1969 até 2019 a Biblioteca José de Alencar cresceu sobremaneira. Seus trabalhos técnicos passaram a ser informatizados através da base de dados Aleph, tanto os serviços de catalogação em 2003, quanto de circulação, em 2010. Em 2016 foi criada a Oficina de Conservação e Restauração. Através de projetos com o SiBI e também com professores da Faculdade de Letras da UFRJ, pretende-se conseguir recursos para digitalizar algumas obras do Museu de Língua e Literatura e também da Coleção Celso Cunha, a fim de preservar acervos, a memória e a história da literatura.
Escândalo na Academia Imperial de Belas Artes: uma expulsão por manifesta desobediência
Authors: Chillón Alberto Martín
Published: January 2020

Em 12 de dezembro de 1838, Bernardo Pereira de Vasconcelos (1795-1850), ministro interino do Império, decidiu o castigo que deveria ser imposto ao aluno de escultura da Academia Imperial de Belas Artes, Honorato Manoel de Lima, por seu descomedido procedimento e manifesta desobediência, excluíndo-o para sempre de dita Academia. Este documento se conserva, assim como a produção documental da Academia Imperial de Belas Artes, no Arquivo Histórico da Escola de Belas Artes da Universidade Federal do Rio de Janeiro, acervo fundamental para o estudo da arte brasileira dos séculos XIX e XX e para a história do ensino artístico no Brasil.
Current researches of haptic perception and applying it into the fields in the psychology of organizational and consumer behavior
Authors: Park InJo , Rie Juil
Published: January 2020

Haptic perception is considered as very important for human being since we can perceive the world and feel emotional stability through it, and also it is one of perceptual channels related to interaction with objects daily life. Traditionally, researches about haptic have been performed in the area of perception. However, recently psychologists who study in the field of social, organization, and consumer behavior deal with the haptic. The purpose of this study was that psychologists taking haptic into their study in the future would use like a tutorial, as reviewing the biological foundation, the perceptual mechanism, and the theoretical issue. Also, the present study introduced studies involving haptic in the areas of general psychology so that it would be possible to extend the concept of haptic and apply into other domains of psychology as well as perception. Finally, the propositions with haptic in the field of both organizational consumer behavior were presented for psychologists of organization and consumer psychology who would be interested in haptic.
Agreement of surgeon's perception of the effectiveness of spinal cord decompression with findings on postoperative magnetic resonance imaging for dogs surgically treated for intervertebral disk extrusion
Authors: Tirrito Federica , Cozzi Francesca , Bonaldi Martina , Conti Sara , Lombardo Rocco
Published: January 2020

OBJECTIVE

To determine the accuracy of the surgeon's perception versus postoperative MRI findings in assessing the effectiveness of spinal cord decompression achieved in dogs surgically treated for intervertebral disk extrusion (IVDE) and whether postoperative MRI findings were more likely to be associated with various outcomes.

ANIMALS

68 dogs surgically treated for cervical or thoracolumbar IVDE.

PROCEDURES

Data on clinical, neurologic, pre- and postoperative MRI, and intraoperative findings as well as outcomes and recovery times (6-month follow-up period) were prospectively collected and compared between various groups.

RESULTS

54 (79%) dogs had thoracolumbar IVDE, and 14 (21%) had cervical IVDE. Median degree of spinal cord compression as assessed on transverse T2-weighted MRI images was 45.6% before surgery and 8.8% after surgery. The correlation between surgeons' perception (n = 3) and postoperative MRI findings for the degree of spinal cord decompression achieved was only fair (κ = 0.40). Unsatisfactory spinal cord decompression as assessed via postoperative MRI was associated with severity of preoperative neurologic grade and preoperative compression, thoracolumbar (vs cervical) IVDE, and ventral (vs ventrolateral or dorsolateral) circumferential distribution of extruded material. Satisfactory (vs unsatisfactory) decompression as assessed via MRI was associated with a lower postoperative neurologic grade, greater likelihood of a successful outcome, and lower mean recovery time.

CONCLUSIONS AND CLINICAL RELEVANCE

Results suggested that for dogs surgically treated for IVDE, the surgeon's perception of adequate spinal cord decompression may be less reliable than postoperative MRI findings. Postoperative MRI appeared particularly useful for dogs with a severe preoperative neurologic status, severe preoperative spinal cord compression, and thoracolumbar IVDE.
Efektifitas Pendidikan Kesehatan Terhadap Tekanan Darah Pada Lansia
Authors: Damayanti Cory Nelia , Hannan Mujib , Fatoni Akhmad Feri
Published: January 2020

The incidence of hypertension especially faced by elderly demands the role of health workers to prevent and promote about healthy. Health education about hypertension for personal can give benefit habits, attitudes and knowledge related to the health of individuals, communities, and nations.

Pre-experimental research design and One-Group Pretest-Posttest Design was used in this research. Population of this research were elderly with hypertension grade I blood pressure in Integrated Healthcare Center located in Pangarangan Village, Sumenep as many as 50 people. The samples of this research were 44 elderly suffered by hypertension. Purpossive sampling technique using inclusion and exclusion criteria approach. Data analysis in this study used the Paired samples t-test.

The results of this study for elderly with blood pressure before given health education have  basic pressure at stage II as many as 18 people (20.5%). Elderly’s blood pressure after given health education mostly at stage I as many as 37 people (42.1%) and effective health education against pressure blood pressure in elderly with hypertension in Integrated Healthcare Center Elderly in Pangarangan Village, Sumenep.

Getting lower education level, getting high the risk of developing hypertension for elderly.
CONSANGUINEOUS MARRIAGE IN ETHNIC MINORITIES AREA - SITUATION AND ISSUES
Authors: Thanh Minh Vu Thi
Published: January 2020

Consanguineous marriage has left many consequences for many families and society, which directly affecting the next generation of the married people. Consanguineous marriage has seriously affected the mothers and children’s health, reducing the quality of the lineage, the quality of population and human resources of ethnic minorities erea. Now, consanguineous marriage has been taking place in ethnic minorities area of our country, especially in remote and isolated areas bordering the Northern Midland and mountainous provinces, North Central and Central Coast areas, Central Highlands.The consequences of consanguineous marriage for the family and society aren't small requiring us to have appropriate and practical solutions and policies to minimize this situation.
RESULTS OF IMPLEMENTATION OF SOME POLICIES ON SOCIO-ECONOMIC DEVELOPMENT FOR KHMER ETHNIC PEOPLE IN THE SOUTHWEST REGION
Authors: Dung Nguyen Duy
Published: January 2020

In the past years, our Party and State have always paid special attention and issued many important guidelines and policies on socio-economic development for Khmer ethnic people, including Directive No.68/CT-TW dated April 18th, 1991 of the Party Central Committee (Session VI) on working in the Khmer ethnic minority area, Directive No.19-CT/ TW of the Secretariat, dated January 10th, 2018 on strengthening work in the Khmer ethnic minority region in the new situation. Thanks to the implementation of many guidelines and policies of the Party and the State, the lives of ethnic minorities in general and the Khmer ethnic people in particular have been increasingly improved, the intellectual level of people has been raised, the rate of poor households decreases year by year. In addition, the work of training cadres and developing party members in the ethnic minority areas has been paid more and more attention.