bluuebunny/crossref_metadata_2025 huggingface dataset:
Salmo 110
Authors: Delgado William
Published: April 2024

A diferencia de los estudios realizados desde la perspectiva de la alta crítica con referencia a Salmo 110, una aproximación al texto, bajo una visión uniforme y unificadora de la Biblia, permite ver que este salmo revela al ’adon escatológico y su misión mesiánica como Rey y Sacerdote. El NT detalla sobre los trazos ya pintados en esta composición davídica y aplica a Cristo esta profecía sagrada de intercesión, juicio y victoria. Por lo tanto, este salmo es una invitación presente para la humanidad extraviada a volverse de sus caminos y apelar al Intercesor que brinda salvación eterna, antes de que el tiempo de gracia finalice y su juicio caiga sobre todos aquellos que no se le sujetaron.
El concepto "uno" en la comprensión de la unicidad de Dios: Una reflexión
Authors: Georgia Mercedes Elias
Published: April 2024

Se puede decir que es la aparición de un concepto numérico vinculado con la Deidad, lo que convierte a Deuteronomio 6:4 en el gran texto estandarte del antitrinitarianismo. Para los teólogos unitarianos o antitrinitarios el término cejad usado en este pasaje, y a lo largo de la Biblia Hebrea, designa una unidad numérica absoluta, por lo que concluyen que hay un solo Dios, y no tres. Este artículo analiza la terminología numérica empleada en las Escrituras para referirse a Dios como "uno", y demuestra que la palabra hebrea cejad, lejos de ser un argumento a favor del concepto absolutista de la unicidad numérica del ser de Dios, se encuentra entre las mayores pruebas en su contra.
¿Cuál es la identidad de la apostasía Omega?
Authors: Hanco Jesus
Published: April 2024

Quienes estudian las profecías del tiempo del fin en los escritos de Ellen G. White ha leído sobre la apostasía omega y las diferentes hipótesis sobre el cumplimiento de esta profecía. Este artículo describe la identidad de la apostasía omega haciendo un análisis histórico-gramatical de cada las cinco declaraciones de Ellen G. White donde se hace referencia a la apostasía alfa y omega. Estos documentos fueron cartas enviadas de manera específica a los líderes del área médica de la IASD, al Dr. Jhon Kellogg y al Dr. A. J. Reed. Aunque no existe una forma sea gramatical o histórica de identificar el tiempo exacto en que se levantará dicha apostasía, la experiencia acontecida con la apostasía alfa y la publicación del libro Living Temple, son una clara vislumbre de la naturaleza que tendría esta futura apostasía.
Macroinvertebrados bentónicos como bioindicadores de calidad en el Lago Titicaca: Bahía Interior de Puno
Authors: SALAMANCA COAQUIRA SANDRA LINDAURA
Published: April 2024

El objetivo del presente estudio fue determinar la calidad del agua de la Bahía Interior de Puno, sector oeste del Lago Titicaca, a partir de observaciones sobre la comunidad de macroinvertebrados bentónicos. Fue ejecutado con periodicidad mensual entre marzo y junio del 2012. Se establecieron nueve estaciones de muestreo en donde se extrajeron muestras de bentos con empleo de draga Ekman. Los índices analizados fueron Shannon-Weaver y Biological Monitoring Working Party Score System (BMWP). La estación con mayor biodiversidad fue la E-1 (Muelle, margen derecho), representada por 6577 individuos y 6 familias, seguida por la E-9 (frente, UNA Puno) con 5200 individuos y 4 familias. La estación E-4 (Bajo el terminal zonal) fue la menos diversa, con 178 individuos y 1 familia, seguida por la E-5 (Laguna de oxidación, izquierda) con 1110 individuos y 3 familias; en la estación de control E-6 (Control, aguas limpias) encontramos 3600 individuos y 2 familias, es la estación en la cual nunca se registraron las familias Chironomidae, Tubificidae, Planorbidae y Ostrácoda. Con el índice de Shannon-Weaver no se encontró diferencias entre estaciones y meses, obteniéndose valores de 0 a 1,3, calificadas como “poco diversa”. De acuerdo al índice biológico BMWP, la calidad del agua en el ámbito de estudio tuvo calificativos entre 2 y 28, “calidad crítica” y “calidad muy crítica” que significan “aguas muy contaminadas” y “aguas fuertemente contaminadas”. Los resultados ponen en evidencia el estado crítico de la calidad del agua en la Bahía Interior de Puno, siendo necesario buscar medidas que permitan su recuperación ambiental.   
Palabras clave: contaminación, aguas negras, biodiversidad, fauna bentónica
Biodegradación de polímeros de plástico por Pseudomonas
Authors: CCALLO ARELA MAGALI , SACACA MASCO FRANKLIN , CALLATA CHURAC ROSE ADELINE , VIGO RIVERA JUAN EDUARDO , CALLA CALLA JAEL
Published: April 2024

La generación de toneladas de plásticos es uno de los problemas ambientales más severos a nivel internacional porque no se deterioran con facilidad, ni se descomponen u oxidan naturalmente con el transcurrir del tiempo por alta resistencia mecánica y por su composición química de cadenas de monómeros de carbono con presencia de aditivos que permiten tener la rigidez. El objetivo de este trabajo fue la revisión bibligráfica sobre los mecanismos, métodos y técnicas en la biodegradación de plásticos por Pseudomonas. La investigación demuestra que las Pseudomonas tienen la capacidad de asimilar los plásticos, convirtiéndolos de polímeros a monómeros y finalmente mineralizarlos en dióxido de carbono o en gas metano. Esta capacidad de asimilación de estos microorganismos se debe a la generación de enzimas que inician la ruptura de polímeros, sin embargo, estos microorganismos no solo poseen la capacidad de asimilación de los polímeros si no que se adaptan a diferentes medios y/o condiciones bióticas y abióticas con mayor facilidad que otras bacterias. Por tanto, las revisiones de literatura demuestran que las Pseudomonas son un medio ecológico de retirar del medio ambiente polímeros como: polietileno de alta densidad (HDPE) y de baja densidad (LDPE), polietileno tereftalato (PET), polietileno (PE), polipropileno (PP), poliuretano (PU), polisulfuro de fenileno (PPS), entre otros polímeros.
 
Palabras claves: plásticos; Pseudomonas; biodegradación de polímeros.
Inseguridad laboral percibida como factor determinante del estrés laboral percibido ante el impacto de la pandemia COVID-19 en trabajadores peruanos dependientes
Authors: Palomino Mariño Clis Oshin
Published: April 2024

La presente investigación tuvo como objetivo determinar la relación significativa entre la inseguridad laboral percibida y estrés percibido ante el impacto de la pandemia COVID-19 en trabajadores peruanos dependientes. Partiendo de dos aspectos teóricos, en primer lugar se enfocó la inseguridad laboral percibida propuesta; y en segundo lugar se analizó los niveles de estrés laboral percibidos. Se consideró tres aspectos: impacto del COVID-19 en las empresas, la inseguridad que percibía el colaborador y el estrés que le generaba. El estudio cuenta con un diseño no experimental de corte transversal, con enfoque cuantitativo de tipo correlacional. Prescindiendo de una muestra no probabilística de acuerdo al número de participantes que dieron respuesta al cuestionario virtual, se aplicó una encuesta de 18 preguntas a 256 trabajares de ambos sexos. Los instrumentos aplicados fueron inseguridad laboral percibida (4 preguntas) y estrés laboral percibido (14 preguntas). El resultado indicó que la inseguridad laboral percibida es un factor determinante en el nivel de estrés percibido en trabajadores peruanos dependientes, mientras se desarrolla la emergencia sanitaria COVID-19.
Representaciones de género en el texto de Lengua y Literatura de tercer año de educación básica
Authors:   Universidad Politécnica Salesiana (Ecuador), Rodríguez Dayana , Esquivel Napoleón ,   Universidad Politécnica Salesiana (Ecuador)
Published: April 2024

Esta investigación trata sobre los estereotipos sexistas en las ilustraciones del texto escolar, pues durante siglos se ha pensado que el sexo masculino supera al femenino en diversos aspectos, mismos que la sociedad aceptó desde el asentamiento del ser humano en la tierra. Los hombres solían encargarse de distintas actividades, entre ellas: llevar el sustento económico y alimenticio al hogar; además, realizaban trabajos que requerían esfuerzo físico y no intervenían en la crianza ni cuidado de los niños. Mientras que, las mujeres, debido a su caracte- rización de sutileza y fragilidad, eran asociadas al cuidado familiar y encargadas del quehacer doméstico (Saldívar et al., 2015). Estos roles distintivos para los sexos: masculinos y femeninos, se han consolidado y continúan representándose en la sociedad (Cerri y Alamillo, 2012); específicamente en la educación, donde acciones entre pares o autoridades, además del material didáctico ocupado por profesores sigue generando estereotipos sexistas.
Perspectivas de género en los textos de Lengua y Literatura y Ciencias Sociales de educación básica
Authors:   Unidad Educativa “Alm. Jorge Cruz Polanco”, Rubio Jazmín , Villamar Jéssica ,   Universidad Politécnica Salesiana (Ecuador)
Published: April 2024

Muchas de las concepciones culturales en respuesta al accionar de cada género se deben a la inmersión de la perspectiva de lo que un hombre o una mujer debe hacer en diferentes ámbitos, como en lo laboral, académico o social. Una fuente de transmisión de este pensamiento se lo identifica de una manera indirecta y lo encontramos en los textos escolares ya que es un instrumento fundamental que influye en la proyección de las desigualdades y es una de las herramientas más importantes de la comunicación de este planteamiento en razón del sexo Terrón y Cobano-Delgado, (2008). Este hecho se lo puede identificar en las ilustraciones ya que son representaciones sociales aceptadas y adaptada a la sociedad y lo que se observa en ellas llega a ser considerado como “normal”, y teniendo el conocimiento que las ilustraciones es el elemento que más atrae la atención de los estudiantes y son elementos reforzadores de valores e ideas y estereotipos.
Pico della Mirandola esete a magyar humanizmussal
Authors: Lázs Sándor
Published: April 2024

A Magyar Királyság apácakolostoraiban a XV. század végének szerzetesi reformjai után a népnyelv volt használatban. A nővérek vulgáris olvasmányait azok a szerzetesek állították össze, akik külföldi egyetemeken tanultak, részben humanista műveltséget szereztek. Többen kísérelték meg kimutatni ezt az erudíciót, de csak úgy sikerült, hogy kitágították a humanizmus fogalmát, hiszen az anyanyelv nem hordozta, a kolostorokban használt bastarda pedig nem tükrözte a humanista kultúrát. Egyetlen fogódzó található népnyelvű kolostori kódexeinkben.

A premontrei Pozsonyi Kódex 1520-as latin nyelvű dedikációjában Giovanni Pico della Mirandola fordulata található meg: summus arcitectus Deus, amely az Oratio de hominis dignitate című művéből származik. A kódex ismeretlen scriptora – nevét kivakarták – más kolostori kéziratban nem található korai humanista kapitálissal kezdte az általa írt szakaszt. Műveltségét ezek alapján humanistának gondolnánk, de forrása nem Pico della Mirandola. A humanista kifejezését a Gymnasium Romanum tanévnyitóján idézte a rektor, Iulius Simon Siculus. Az eseményen egy olyan magyar diák is részt vett, akit a magyar premontreiek rendi elöljárója küldött Rómába jogi tanulmányokat folytatni. A magyar diák, Bessei Farkas Ignác volt, aki Fegyverneki Ferenc sági prépostnak ajánlva kiadta az ünnepi beszédet: Oratio de inventione artium liberalium Romae in die Sancti Lucae in templo divi Eustachii habita per Siculum (Romae, 1516), amely így a rendi elöljáró környezetében is terjedt. Bessei Farkas Ignác királyi jegyző lett, a várakozásokkal ellentétben okleveleinek írása nem egyezik a Pozsonyi Kódex dedikációjának ductusával, más volt a scriptor.
Körmendy Kinga, Lauf Judit, Madas Edit, Sarbak Gábor, Az Esztergomi Főszékesegyházi Könyvtár, az Érseki Simor Könyvtár és a Városi Könyvtár kódexei, szerk. Madas Edit, Esztergom, Budapest, Esztergomi Főszékesegyházi Könyvtár, Akadémiai Kiadó, OSZK, 2022
Authors: Monok István
Published: April 2024

Több szempontból is újító vállalkozás két kötetét tartjuk a kezünkben. Pontosabban megújuló, vagy mondjuk, változó vállalkozásét. A 2024-ben ötvenéves Fragmenta Codicum kutatási program Mezey László, Vizkelety András, Madas Edit és most Sarbak Gábor irányítása alatt többféle, szakmailag mindig indokolható változtatásokat eszközölt munkája eredményének kiadásakor. 2021-re már világossá vált, hogy a nemzetközi szakmai érdeklődésre számot tartó kódexkatalógus nem jelenhet meg csak magyarul és csak latinul sem. Nem meglepő, hogy a nemzetközi szakma képviselői nem tanulnak meg magyarul, latinul pedig sokszor már kényelmetlen dolgozni. Ha a szerkesztőcsapat a korszellemmel akart volna úszni, akkor angolul adja ki a kötet idegennyelvű változatát, azonban a német fordítás melletti döntésnek alapos szakmai okai vannak. A sorozat VI. kötetében (2007) a kutatócsoport már szigorúan a németkutatási alap (Deut sche Forschungsgemeinschaft) ajánlásai mellett kötelezte el magát a kódexek és a fragmentumok leírásában, és nemzetközi érdeklődésre is elsősorban a német nyelvterületről, illetve a német kulturális terület (Köztes-Európa) országaiból számíthatnak.
Réka Tímea Újlaki-Nagy, Christians or Jews? Early Transylvanian Sabbatarianism (1580−1621), Göttingen, Vandenhoeck & Ruprecht Verlage, 2022 (Refo500 Academic Studies, Volume 87)
Authors: Nagy Kornél
Published: April 2024

Régi adóssága volt a nemzetközi tudományosságnak egy olyan monográfia megírása, amely az erdélyi szombatosok (sabbatarii) kora újkori múltját és műveltségét dolgozta fel. Ezt a hiátust tölti be Újlaki-Nagy Rékának a tavalyi esztendőben megjelent vaskos terjedelmű és egyúttal angol nyelvű kötete.
Desastre lento: una falsa elegía
Authors: Ganitsky Tania
Published: April 2024

Este artículo de reflexión responde a una invitación que me fue hecha para escribir sobre el rol de lo ecológico en mi práctica como poeta, específicamente como autora del poemario Desastre lento, cuya primera edición fue publicada en 2017 y, la más reciente, en 2023. En el lapso de estos años, crítica y poéticas ecológicas han cobrado fuerza en el terreno de los estudios literarios y de la creación poética. De tal manera, en este artículo voy a reflexionar sobre los poemas del libro que considero más tocan las fibras de lo ecopoético a través de preguntas por la animalidad, la catástrofe ambiental y las narrativas del fin del mundo. Los comentaré a través de ejercicios de close reading con un enfoque interdisciplinar
ИССЛЕДОВАНИЕ ВОЗМОЖНОСТИ ИСПОЛЬЗОВАНИЯ МЕТОДА ВЛАЖНОЙ ГРАНУЛЯЦИИ В МИКСЕРЕ-ГРАНУЛЯТОРЕ С ВЫСОКИМ УСИЛИЕМ СДВИГА ДЛЯ ПОЛУЧЕНИЯ ЯДРА ТАБЛЕТКИ, СОДЕРЖАЩЕГО ЦИТИКОЛИН С ПРОЛОНГИРОВАННЫМ ВЫСВОБОЖДЕНИЕМ
Authors:   Волгоградский государственный медицинский университет, САЛАХЕТДИНОВ Д.Х. , СЫСУЕВ Б.Б. ,   Первый Московский государственный медицинский университет имени И.М. Сеченова
Published: April 2024

В рамках фармацевтической разработки комбинированной таблетки цитиколина и мемантина проведено исследование возможности получения таблеток ядер, содержащих цитиколин, методом влажной грануляции с усилием сдвига. Получены модельные образцы таблеток и проведены технологические исследования гранулята и таблеток-ядер. Показана целесообразность применения испытуемого метода для получения ядра, содержащего цитиколин, и выбраны перспективные модельные составы для дальнейших исследований.
ИССЛЕДОВАНИЕ ФАРМАКОКИНЕТИКИ ЛЕКАРСТВЕННЫХ СРЕДСТВ, ПРОИЗВОДНЫХ АКОНИТА БЕЛОУСТОГО (ACONITUM LEUCOSTOMUM WOROSCH) И АКОНИТА СЕВЕРНОГО (ACONITUM SEPTENTRIONALE KOELLE)
Authors:   Общество с ограниченной ответственностью «Центр фармацевтической аналитики», АРЧАКОВА О.А. , КОМАРОВ Т.Н. , ШОХИН И.Е. , БАГАЕВА Н.С.
Published: April 2024

Целью исследования являлась разработка и валидация методики определения лаппаконитина и N-дезацетиллаппаконитина в плазме крови человека для изучения фармакокинетики препарата лаппаконитина гидробромида, таблетки пролонгированного действия 25 мг.
ПРОБЛЕМЫ ПРАКТИКО-ОРИЕНТИРОВАННОГО ОБУЧЕНИЯ КЛИНИЧЕСКОЙ ФАРМАКОЛОГИИ НА ФАРМАЦЕВТИЧЕСКОМ ФАКУЛЬТЕТЕ И ПУТИ ИХ РЕШЕНИЯ
Authors:   Воронежский государственный медицинский университет им. Н.Н. Бурденко, Н.Ю. Н.Ю. , ЧЕРЕНКОВА О.В. , БАТИЩЕВА Г.А.
Published: April 2024

Формирование профессионально-значимых компетенций провизора требует комплексного подхода к процессу обучения, включая четкую сопряженность самостоятельной работы и аудиторных занятий. Эффективная организация внеаудиторной работы студентов включает сочетанное использование «традиционных» методов обучения (изучение теории, решение задач, тестов) и активную работу с общедоступными электронными платформами и источниками информации. Повышение мотивации к обучению возможно путем использования проектных форм обучения, а также ролевых игр на тематику, актуальную для будущей профессиональной деятельности.
An assessment of marital adjustment in patients with rheumatoid arthritis
Authors: Resorlu Hatice , Sahin Basak , Ertekin Hulya , Bilim Serhad , Savas Yılmaz
Published: April 2024

Aim
 To investigate marital adjustment in patients with rheumatoid arthritis and factors affecting this.
Methods
 A total of 32 patients diagnosed with Steinbrocker class 1-2 rheumatoid arthritis and 32 healthy individuals from a similar age group were included. Sociodemographic characteristics, the Beck Depression Inventory (BDI), short–form 36(SF-36) and the dyadic adjustment scale (DAS) were evaluated in both groups. A visual analogue scale (VAS), the disease activity score 28 (DAS28) and a health assessment questionnaire (HAQ) were also investigated in the patient group.
Results
 Mean ages were 46.5±9.2 years in the patient group and 47.7±8.1 in the control group (p=0.5). No significant difference
was determined between the two groups in terms of sociodemographic characteristics. No statistically significant correlation was observed between erythrocyte sedimentation rate (ESR), patient and physician global VAS, DAS28, HAQ and morning stiffness and DAS total score. Comparison of DAS subunits revealed a significant difference in dyadic satisfaction and affectional expression in the patient and control groups (p=0.046 and p=0.037). A statistically significant negative correlation was observed between duration of the disease and marital adjustment (p=0.01;r= -0.58).
Conclusion
Due to its progressive and prolonged course rheumatoid arthritis can also affect individuals’ social relationships besides restricted daily living activities. Activation of rheumatoid arthritis did not affect marital adjustment in this study, but adjustment decreased with duration of the disease.
Role of echocardiography in diagnosis and management of complete papillary muscle rupture caused by myocardial infarction
Authors: Vincelj Josip , Biočić Stanko , Udovičić Mario , Sičaja Mario , Jakšić Jurinjak Sandra
Published: April 2024

Aim
 To evaluate the usefulness of echocardiography in the diagnosis of complete rupture of papillary muscle.
Methods
Transthoracic (TTE) and transesophageal echocardiography (TEE) was performed with the ATL 3000 HDI Ultrasound
Inc (Bothell, WA, USA) with a 2.5 MHz transducer and 5-7 MHz multiplane phased array transducer. We are reporting about two patients (a 45 and a 51-year old male) with complete ruptures of papillary muscle following acute myocardial infarction (AMI).
Results
 Both patients were previously treated with fibrinolysis in their local hospitals, 400 and 300 km, respectively, away from our
hospital. Massive mitral regurgitation developed in both followed by rapid deterioration of hemodynamic state and severe heart failure, because of which both were transferred by helicopter to the Coronary Care Unit of our clinic. The diagnosis of complete papillary muscle rupture was confirmed in both patients by TTE and TEE. Due to the significant deterioration in their hemodynamic state, vasoactive drugs and intra-aortic balloon pump support were applied. Both patients then underwent mitral valve replacement, accompanied by concomitant coronary artery bypass grafting in
one case.
Conclusion
 Transesophageal echocardiography is a more accurate and rapid diagnostic method in patients with mechanical complications of AMI than TTE.
Efficacy of chronic statin therapy on major cardiac events after coronary artery bypass grafting: low-dose versus high-dose
Authors: Kunt Ayşegül , Özcan Sedat , Küçüker Aslihan , Odabaşi Dolunay , Kunt Alper Sami
Published: April 2024

Aim
 To investigate whether chronic statin treatment after coronary artery bypass grafting (CABG) protects patients from major
cardiac events and provides percutaneous coronary intervention (PCI) free survival.
Methods
A total of 232 patients with previous CABG and chronic statin therapy were selected retrospectively and were divided into
two groups according to a dosage of atorvastatin per day, e. g., 20 mg or 40 mg. Groups were compared for the major cardiac events and freedom from PCI by Kaplan Meier analysis as the primary end point. Patency of grafts including left internal thoracic artery (LITA) and saphenous vein (SVG) and progression of non-grafted native vessel disease were also evaluated as secondary end points.
Results
 Cardiac mortality, periprocedural myocardial infarction (MI), target vessel revascularization and percutaneous coronary intervention free survival were as follows: 2.9% versus 2.1% (p=1.000); 16.1% versus 21.1% (p=0.331); 56.93% versus
52.63% (p>0.005); 58.4% versus 63.2% (log-rank test; p= 0.347) in atorvastatin 20 mg and atorvastatin 40 mg groups, respectively. However, these results were not statistically significant between two groups (p>0.005). Patency of openness of grafts including LITA and SVG and progression of non-grafted native vessel disease were similar between groups (p=0.112, p=0.779, p=0.379 and p=0.663, respectively).
Conclusion
Low-dose long-term statin treatment had similar outcomes on major cardiac events and identical rate of freedom
from percutaneous coronary intervention after coronary artery bypass grafting compared with high-dose long-term statin treatment. It is better to start from low dose statin treatment after surgical interventions.
Incidence of endophthalmitis after intravitreal application of anti VEGF therapy at the University Clinical Center in Tuzla, Bosnia and Herzegovina
Authors: Terzić Svjetlana , Pilavdžić Adisa , Nadarević Vodenčarević Amra
Published: April 2024

Aim
 To report the incidence of endophthalmitis following the use of intravitreal injection of anti- vascular endothelial growth factor
(anti VEGF) therapy.
Methods
 In this retrospective study a total of 986 intravitreal bevacizumab injections were applied between January 2008 and
April 2015 at the University Clinical Center Tuzla, Bosnia and Herzegovina (B&H). Since January 2012, a total of 55 intravitreal ranibizumab injections were applied and since October 2014, 60 intravitreal aflibercept injections were applied to patients.
Results
 Two cases of endophthalmitis following intravitreal injection of bevaciuzumab occurred and none after ranibizumab or
aflibercept. The overall incidence of clinical endophtahlmitis was 0.2%.
Conclusion
 The results suggest that a low rate of endophthalmitis can be achieved by means of a protocol. This is a very important
study as it is the first of this kind in B&H that documents the incidence of endophthalmitis after intravitreal application. Currently, bevacizumab in B&H is most frequently used intravitreal anti-vascular endothelial growth factor due to very low price.
Sedation for transesophageal echocardiography: comparison of propofol, midazolam and midazolam-alfentanil combination
Authors: Huseyin Toman , Erkılınc Atakan , Kocak Tuncer , Guzelmeric Fusun , Faruk Savluk Omer , Dogukan Mevlut , Acar Goksel
Published: April 2024

Aim
 The administration of trans esophageal echocardiography (TEE) may cause nausea, shortness of breath, agitation, emotional distress and pain in patients due to pharyngo-esophageal intubation, which may be partially relieved by sedoanalgesia. The aim of this study was to compare clinical effects of midazolam, midazolam-alfentanil combination and propofol sedation given for sedation and sedoanalgesia to patients with planned diagnostic TEE
interventions.
Methods
This study was prospectively completed with 90 randomized adult patients in ASA risk groups I-II-III. Group M were
given 2.5 mg midazolam, group MA were given 1 mg midazolam and 5 μg/kg alfentanil and group P were given 0.5 mg/kg propofol intravenous bolus. If necessary, additional doses were administered. Patients administered with TEE were evaluated in terms of additional dose requirements, Ramsey Sedation Scale (RSS), modified Aldrete Scoring (MAS), recovery time and duration of stay in the hospital.
Results
 In the group P additional dose requirements were greater (p<0.05), as well as the duration of stay in the recovery unit and
hospital were shorter (p<0.05). On insertion of the TEE probe, the RSS in the group P was clearly higher than in other groups M and MA (p<0.05).
Conclusion
 During the TEE intervention, the use of propofol, contrary to requirements for additional dose and observation of
apnea, appears to be advantageous due to providing more rapid and effective sedation depth without a need of expensive antagonist agents, and allowing early discharge of patients. Additionally, it seems that the use of midazolam combined with alfentanil, is more advantageous comparing to midazolam alone.
Factors affecting mortality in emergency surgery in cases of complicated colorectal cancer
Authors: Kızıltan Remzi , Yılmaz Özkan , Aras Abbas , Çelik Sebahattin , Kotan Çetin
Published: April 2024

Aim
 To evaluate retrospectively demographic, clinical and histopathological variables effective on mortality in patients who had
undergone emergency surgery due to complicated colorectal cancer.
Methods
A total of 39 patients underwent urgent surgical interventions due to complicated colorectal cancer at the Department
of General Surgery, Dursun Odabaş Medical Center, between January 2010 and January 2015. Thirty three of these were included in the study. Six patients were excluded because complete medical records had been missing. Medical records of the 33 cases were retrospectively reviewed.
Results
There were 14 (42.5%) male and 19 (57.5%) female patients. Mean age was 60 years (range: 32- 83 years); 14 (42.5%) patients were less than 60 years old , while 19 (57.5%) were 60 years old or older. Operations were performed due to perforation (39.3%) and obstruction (60.6%) in 13 and 20 patients, respectively. Tumor localization was in the right and transverse colon in nine (21.2%) and in the left colon in 24 cases (72.7%). Eleven (33.3%) patients underwent resection and anastomosis, 13 (39.3%) resection and ostomy, and nine (27.2%) patients underwent ostomy alone without any resection. Postoperative mortality occurred in nine cases (27.2%).
Conclusions
High mortality should be expected in females older than 60 years with a left sided colon tumor or with another synchronous tumor and in perforated tumors. Unnecessary major resections should be avoided and primary pathology should be in the focus of treatment in order to decrease the mortality and morbidity
rates. 
Does odor and taste identification change during hyperemesis gravidarum?
Authors: Yasar Mehmet , Sagit Mustafa , Zeki Uludag Semih , Ozcan Ibrahim
Published: April 2024

Aim
To investigate a difference in odor and taste identification among pregnant women with hyperemesis gravidarum, those with healthy pregnancy and non-pregnant women.
Methods
 This prospective, controlled study included 33 pregnant women with hyperemesis gravidarum, 33 healthy pregnant and 26
non-pregnant women. For all participants, rhinological examinations were performed. Odor and taste identification were performed by holding Sniffin Sticks test battery (Burghart, Wedel, Germany) in all participants.
Results
 There was a statistically significant difference in results of odor identification tests among the groups (p=0.031). Rose odor
was selected as the most pleasant odor by the hyperemesis gravidarum group, 32 (96.9%). Orange odor was selected as the most pleasant odor by the healthy pregnant women, 33 (100%) whereas the banana odor was selected as the most pleasant odor by the healthy non-pregnant women, 10 (38.4%). In taste identification tests, there was a significant difference in total taste scores among the groups (p=0.003).
Conclusion
It is obvious that there is a need to evaluate odor thresholds and other parameters by detailed studies on odor perception
in the context of hyperemesis gravidarum. 
Antimicrobial efficacy of probiotic-containing toothpastes: an in vitro evaluation
Authors: Parčina Amižić Ivana , Cigić Livia , Gavić Lidia , Radić Marina , Biočina Lukenda Dolores , Tonkić Marija , Goić Barišić Ivana
Published: April 2024

Aim
 To evaluate, in vitro antimicrobial ability of two probiotic toothpastes (one containing Lactobacillus paracasei, other containing Lactobacillus acidophilus) and one toothpaste without probiotic separately, and in a combination with two different mouthrinses (one containing essential oils and the other containing hexitidine).
Methods
Antimicrobial susceptibility was checked by using the ditch method and Clinical Laboratory Standard Institute (CLSI)
guidelines. Two different toothpastes with probiotic, toothpaste without probiotic and two different mouthrinses were tested against the following selected microorganisms: Candida albicans, Candida tropicalis, Enterococcus faecalis, Streptococcus salivarius and Staphylococcus aureus. Kruskal-Wallis test and MannWhitney U test were used for the statistical analysis (p≤ 0.05).
Results
 Probiotic toothpastes had better inhibitory effect than toothpaste without probiotic in the case of Candida albicans
(p=0.043) and Streptococcus salivarius (p=0.043). In all cases, toothpastes had stronger inhibition capacity than mouthrinses
(p≤0.05).
Conclusion
 Probiotic toothpastes, as a relatively new concept in the prevention of oral infectious diseases such as caries and periodontal disease, can contribute to the prevention of oral infectious diseases. 
Poultry products enriched with nutricines have beneficial effects on human health
Authors: Kralik Gordana , Kralik Zlata
Published: April 2024

The paper presents nutritive value of broiler meat and table eggs, as these animal products are used for human nutrition on a daily basis. In the Republic of Croatia, average consumption of poultry meat amounts to 18.3 kg and to 160 eggs per capita.The most quality parts of broiler carcass are breasts and drumsticks with thighs. Breast muscles contain 21-23% protein, 1.90-1.97% fat, 75.28- 76.01% water and 0.74-0.77% collagen. Thigh muscles contain 4.70-6.05% fat, 19.03-19.93% protein and 0.91-1.13% collagen. White meat contains more potassium and magnesium and less zinc and iron than dark meat. In 100 g of edible egg part there is 12.5-13.5 g protein, 10.7-11.6 g fat and 1.0-1.1 g minerals. Caloric valueof eggs is 167 Kcal. Eggs contain high amount of essential amino acids, especially leucine, isoleucine, lysine, arginine, valine and phenylalanine. Furthermore, eggs contain many vitamins, especially A, D, E, K and B-complex, as well as various macroelements and microelements. Eggs and meat enriched with one or more functional ingredients – nutricines (polyunsaturated fatty acids n-3), eicosapentaenoic acid, docosahexaenoic acid, selenium and lutein) meet the criteria of functional food because of their added value and benefits for human health.
Relationship of recovered hepatitis B infection with appearance of toxic propylthiouracil hepatitis
Authors: Čalkić Lejla , Bajramović-Omeragić Lejla
Published: April 2024

Aim
To investigate the relationship between recovered hepatitis B infection with appearance of toxic propylthiouracil (PTU) hepatitis and point out the growing importance of the use of drugs in the development of hepatitis.
Methods
A case of a 45-year-old female patient with suspicion of acute viral hepatitis who had polypragmasy of drugs in the last ten
years, due to the polymorphism of symptoms/illnesses (diabetes mellitus, depression, hypertension, hypothyroidism) was presented.
Results
 A female patient had hyperthyroidism after resolved viral hepatitis B with HBsAg seroconversion (HBsAg negative, antiHBs positive). PTU had the greatest potential for hepatotoxicity of all administered drugs. After corticosteroid therapy there was a
significant improvement in liver function tests. In the course of the disease there was no change of hepatitis markers and exacerbations of hepatitis B.
Conclusion
 Clinical practice should comprehensively monitor the effects of the intricate and tight connection between drugs, liver
and endocrine system in order to better resolve all manifestations, complications and worsening of one or another organic system.
Relación entre la velocidad de lanzamiento y la fuerza específica evaluada a través de dinamometría electromecánica funcional (DEMF) en jugadores de balonmano
Authors: Aguilar Sánchez Javier , Ruiz-Orellana Lorenzo , Chirosa-Ríos Luis Javier , Enrique Lozano Zapata Rafael , Bustos Viviescas Brian Johan , Chirosa-Ríos Ignacio , Rodríguez-Perea Ángela , Morenas-Aguilar María Dolores
Published: April 2024

Objective. To study the relationship between the specific strength in handball, assessed with Functional Electromechanical Dynamometer (FEMD), and throwing velocity. Methods. Thirteen Spanish elite handball players were evaluated (28.77 ± 4.81 years, 90.19 ± 13.07 kg y 1.86 ± 0.10 m) during the preseason. A day of familiarization with the throwing velocity and strength test with FEMD was performed. One week later, the assessment of specific strength, including the upper and lower body (unilateral pullover test and step forward test) and throwing velocity was conducted by the subjects. Results. Significant correlations were found between (i) throwing velocity peak and isometric strength mean in unilateral pullover test with the dominant hand (r = 0.548, p = 0.05), and (ii) between throwing velocity peak and step forward test with the dominant leg (r = 0.628, p = 0.02). Conclusion. Training exercises closer to real game situations are positively related to performance enhancement in handball players. Therefore, the use of devices that allow the assessment and training at the same time in specific situations, should be extended in the sport coaches and researches.
La recreación, habilidades sociales y estrategias de afrontamiento en adolescentes mexicanos durante la primera etapa del confinamiento por Covid-19
Authors: Medina Valencia Rossana Tamara , Salazar C. Ciria Margarita , Andrade Sánchez Adriana Isabel , Ramos Carranza Isela Guadalupe , Reynoso Sánchez Luis Felipe
Published: April 2024

The Mexican General Health Council in March 2020 recognized the SARS-CoV2 epidemic as serious and of priority attention, establishing preventive measures and calling for confinement. This paper focuses its attention on an adolescent population, who by nature are in search of mobilization outside the family and independence. The objective stated to analyze the relationship of recreational activity of Mexican adolescents during the first stage of COVID-19 confinement (March-July 2020) with handling social skills and coping strategies. The research design corresponds to the non-experimental empirical type; For the collection of information, an ad hoc questionnaire was designed that integrated three instruments: Questionnaire on recreation in adolescents in a situation of confinement, Validated Scale of Social Skills by its acronym EHS and Coping Scales for adolescents (ACS). Said instrument had a reliability of Cronbach's Alpha of α=.962 and a Kaiser-Meyer-Olkin coefficient of .969. The selection of the sample was probabilistic, made up of 444 Mexican adolescents from the western zone between 12 and 17 years old, 57.4% women and 42.6% men. The main findings show positive relationships between social skills and coping strategies. Being recreational activities a social support resource that allowed effective coping during the pandemic. 88.1% of the students had enough free time to carry out recreational and physical-sports activities such as exercising or moving (67%), jogging (57.9%), training a sport (57.7%) and taking walks to the open air (50.7%). The most frequently performed recreational activities were listening to music, sleeping, and watching television. Likewise, it was found that women obtain better results than men in Social Skills; differences were found in the Search for Expert Support, with high school students being the ones who most resort to this measure and; finally, a positive association was found between the Coping Activities used by adolescents and Social Skills. This corroborates that the empowerment of adolescents in the positive and active use of leisure and recreation allows better coping and management of social skills, in other words, a mechanism for containment in a situation of youth crisis or social coexistence.
EFECTOS DE UN PROYECTO INTERDISCIPLINAR DE PROMOCIÓN DE COMPORTAMIENTOS SALUDABLES EN ESTUDIANTES DE EDUCACIÓN PRIMARIA DE UN COLEGIO RURAL
Authors: Millán-Navarro Isabel , Sevil-Serrano Javier , Tapia-Serrano Miguel Ángel , Abós Ángel
Published: April 2024

Although the benefits associated with a healthy lifestyle are known, a large percentage of young people do not comply with the established recommendations for the different healthy behaviors, especially during Covid-19. Thus, the aim of this study was to design, implement, and evaluate the effects of a multicomponent and multilevel school-based program on multiple health-related behaviors in Primary Education students. For this, 12 students (M=10.33±1.07), from a multilevel Primary Education classroom of a rural school in Teruel, participated. This five-week program aimed to raise awareness about the importance of adopting a healthy lifestyle. The results showed an increase in daily physical activity and perceived health status after participating in the intervention program. Likewise, recreational screen time also showed a significant decrease. However, the students did not report significant differences in sleep duration, adherence to the Mediterranean diet, and quality of life. Thus, it seems convenient to develop multicomponent, multibehavioral, and multilevel school programs, involving different subjects and areas of action, as well as the entire educational community, to improve these healthy behaviors in young people from rural schools.
La historia del Rugby en España, IIª Parte. De 1924 hasta la II República
Authors: Torrebadella-Flix Xavier
Published: April 2024

Following the establishment of rugby in Catalonia at the beginning of the 1920s, it was also introduced in the “Central region”. This coincided with the dictatorship period of Miguel Primo de Rivera, a time when the first federation matches between Barcelona and Madrid were taking place. There were underlying personal interests at the heart of the question but also conditioning political factors. The objective is to continue to provide information about the development of Spanish rugby, but taking into account the social and political setting of that time in history. This is made possible through an exploration of the historical sports and news press but also a review of other studies that are pertinent to the contextualisation. It is concluded that during the dictatorship Spanish rugby found itself in a difficult centralised and repressive political context, which produced a hostile environment for any manifestation of Catalan sporting nationalism. While the hegemony of Catalan rugby was never in question, by the 1930s the sport had also become firmly rooted in university settings in the Spanish capital.
Introducción y consolidación de los cuentos de Perrault en España / Introduction and consolidation of Perrault's tales in Spain
Authors: Martens Hanna V. L.
Published: April 2024

ResumenEl presente artículo expone la génesis y la consolidación de las traducciones en lengua castellana de los Cuentos de Perrault en el mercado español. Para ello, se han recopilado 37 ediciones que contienen un mínimo de siete de los ocho cuentos en prosa del autor francés, desde 1824, año de la primera traducción española, hasta 1975, año en que termina el franquismo. Se analizan los datos bibliográficos de las ediciones, las relaciones entre las diferentes ediciones, los diferentes cuentos que contienen los volúmenes y la variación y gradual homogeneización en los títulos de los cuentos. El estudio demuestra que la introducción de las traducciones de Perrault en España arranca de manera lenta y tardía, pero paulatinamente el autor y su obra maestra van siendo más conocidos, para convertirse en un verdadero clásico de la literatura infantil y juvenil en España a partir de los años treinta-cuarenta del siglo XX. AbstractThis article discusses the genesis and consolidation of the Spanish translations of Perrault’s fairy tales in Spain. Therefore, 37 editions have been compiled that contain a minimum of seven of the eight prose tales of the French author, from 1824, the year of the first Spanish translation, until 1975, marking the end of the Franco regime. The bibliographic data of the editions, the relations between the different editions, the different tales that are included in the books and the variation and gradual homogenization in the titles of the tales are analysed. The study shows that the introduction of Perrault’s translations in Spain starts slowly and late, but gradually the author and his masterpiece become more known, and by the thirties-forties of the twentieth century, the tales have become a true classic of children’s literature in Spain.
La Ortografía en Secundaria y Bachillerato: Análisis de los errores más frecuentes en letras / Orthography in Compulsory Secondary Education: Analysis of the misspellings
Authors: Cánovas Cánovas María
Published: April 2024

Resumen: El objetivo de esta investigación, tras un estudio de la enseñanza de la ortografía, es analizarlos errores presentes en las letras en estudiantes de 4º de ESO y 2º deBachillerato del instituto Juan de la Cierva y Codorníu ubicado en laRegión de Murcia. Con este propósito, se recogió una muestra total de 113escritos. Así, se sometió a los alumnos de Secundaria a la realización de unaredacción a partir de una imagen y a los estudiantes de Bachillerato a laelaboración de un comentario crítico sobre un texto periodístico. Con todo,se ha podido comprobar que los métodos didácticos empleados en lasaulas y las distintas normas ortográficas no acaban con las dudaspresentes en los hablantes y, por supuesto, no evita los errores quesiempre se encuentran en mayor o menor medida en la escritura.Palabras clave: escritura; ortografía;didáctica; redacciones y comentarioscríticos académicos; errores frecuentes en las letras.

Abstract: The aim of this investigation, after a study of teachingorthography, is to analyse the misspellings made by students of 4thgrade of ESO and 2nd (last year) of secondary school attending the IESJuan de la Cierva and Codorníu located in the Region of Murcia. Forthis purpose, a total sample of 113 essays was collected. As part of thisresearch, the ESO students were asked to write an essay about an image thatthey were presented with, while the other group was required to write acritical piece about a newspaper article. In short, it has been found thatthe teaching methods used in the classroom and the different spellingrules taught do not eliminate the doubts on the speakers’ minds and, ofcourse, do not prevent errors that are always found, in varying, degrees intheir writings.

Keywords: writing; spelling; teaching; academic essays and criticalcomments; common misspellings.
Protocol OCPRIP v1
Authors: Parravicini Chiara , Spedicati Daniele , Guenci Matteo , Liggeri Nicole
Published: April 2024

We present a step-by-step methodology for the systematic extraction, alignment, and analysis of peer review data from Crossref to enhance the OpenCitations Index. The protocol delineates four key phases: data gathering, alignment, data management and data analysis. In the data gathering phase, peer review data is extracted from Crossref, annotated, and organized into JSON format. The alignment phase adapts the OpenCitations Index workflow to treat peer reviews as first-class data entities, generating CSV files for reviews and provenance. These datasets are then converted into RDF format, adhering to the OpenCitations Data Model. Furthermore, the protocol addresses data management by querying OpenCitations Meta database via SPARQL to identify existing peer reviews. This process facilitates the categorization of peer reviews into those already present in the OpenCitations repository and those requiring inclusion. Continuous synchronization with Crossref ensures the currency and accuracy of the dataset. Lastly, data analysis tasks are outlined, including isolating venues, counting DOIs, and verifying article DOIs.
Endosomal, lysosomal, mitochondrial, or Golgi immunoprecipitation for quantitative proteomics v1
Authors: Wade Harper J. , R R Hollingsworth Louis , Lee Chan
Published: April 2024

Previous studies have developed methods for the immunoisolation of lysosomes, mitochondria, EEA1-positive endosomes, Golgi, and other organelles from non-denaturing / non-detergent extracts. Here we describe our most up-to-date protocols for these approaches. Specifically, we describe methods to isolate lysosomes, mitochondria, EEA1-positive endosomes, Golgi, and the preparation of peptides for proteomics applications. We structure our protocol with a modular framework for the future addition of new cell types and organelle-IPs by anyone in the community.
FFPE Tissue Processing for Multimodal Imaging Assays (Phenocycler-Fusion + H&E) following Xenium In Situ Gene Expression v1
Authors: Sivajothi Santhosh , Soja Emily , Bhargava Shruti , F Flynn William , T Courtois Elise
Published: April 2024

Xenium In Situ Gene Expression assay from 10X Genomics enables multiplexed imaging of RNA transcripts in situ. There are several antibody based multiplexed imaging technologies that enable multiplexed protein detection. Hematoxylin and Eosin (H&E) staining is a gold standard method for observing tissue morphology. In order to generate a highly multimodal imaging dataset, we developed a protocol to prepare tissue slides for multiplexed imaging on the Phenocycler-Fusion platform and H&E staining following a Xenium run. Although the Xenium protocol includes a decrosslinking step which is akin to antigen retrieval, a second round of antigen retrieval, as outlined in this protocol, is necessary for epitope unmasking and accurate protein detection by antibody based methods. The steps for slide storage and tissue processing for multiplexed imaging can also be applied to imaging assays on other platforms.
Femininos na arte latino-americana
Authors:   Universidade do Estado do Rio de Janeiro, Dutra da Silva Carolina Carvalho , Caldas Heloisa ,   Universidade Federal Fluminense
Published: April 2024

O presente artigo aborda como tema uma pesquisa em andamento na interface arte e psicanálise. Fundamentado na leitura dos textos de Sigmund Freud e Jacques Lacan, parte dos pressupostos estabelecidos na interface entre arte e psicanálise. Apoiando-nos nas ideias desenvolvidas pelos autores sobre a posição feminina, seis trabalhos de artistas latinas serão tomados neste texto como fio condutor com o intuito de discutir se haveria relação entre essas obras e o impossível da representação simbólica do feminino. O objetivo não é determinar uma forma de olhar para o trabalho dessas artistas nem se tratará nunca de uma tentativa de explicar suas criações, mas a intenção é percorrer algumas produções artísticas buscando o que estas podem nos ensinar sobre a questão do feminino.