bluuebunny/crossref_metadata_2025 huggingface dataset:
Primer día de clase: comenzando a andar desde la cooperación, la politización y la visibilización de las desigualdades de género
Authors: Gurrutxaga Igor Ahedo
Published: April 2022

Este texto pretende hacer frente a dos retos de la Educación superior: centrar el marco del aprendizaje en el alumnado y hacerlo con una perspectiva de género. Situado en la intersección de ambas aspiraciones, se busca aportar herramientas que hagan visible al alumnado las lógicas sobre las que descansa un aprendizaje cooperativo que aborde las desigualdades de género en las aulas. Para ello, el primer contacto con el alumnado en la presentación de una asignatura se antoja un momento clave porque los estudios demuestran cómo las primeras horas en la docencia de una asignatura influyen la motivación para aprender a lo largo del curso. Desde esta atalaya, y tras delimitar los elementos nucleares del aprendizaje centrado en el alumnado y la perspectiva de género aplicada a educación superior, se describe una experiencia implementada las dos primeras horas de presentación de una asignatura del primer curso de Sociología y Ciencia Política que, asentada en una batería de técnicas activas en las que la emoción, el simbolismo y la confianza es clave, permite desde el primer contacto (i) evidenciar las desigualdades en el aula, (ii) enmarcar la metodología y algunos de los contenidos centrales de la asignatura, y (iii) vivenciar desde la práctica el sentido de lo político. Entendido el aprendizaje como un proceso político en el que la cooperación es esencial, este texto presenta un modelo en el que la centralidad está en un alumnado que al que se aspira a motivar para ser protagonista de su aprendizaje en igualdad.
Interface behaviour of carbon-fabric-reinforced cementitious matrix composites with ICCP technique
Authors: Feng Ran , Zhang Jingzhou , Li Yanwen , Zhu Ji-Hua
Published: April 2022

This paper studies the interface bonding performance of carbon-fabric-reinforced cementitious matrix (C-FRCM) composites with the impressed current cathodic protection (ICCP) technique. Single shear tests and pull-out tests on the C-FRCM composites are launched. Three current densities of 0, 100 and 150 mA/m2 in the ICCP technique are considered. The resistance–slip relationships for all the composites are presented. It is found that the maximum resistance of the specimens in the pull-out tests decreases significantly with the increase of current density in the ICCP technique. Moreover, numerical analyses are conducted to obtain a simplified interface bonding stress–slip relationship of the specimens in the pull-out tests.
Antimicrobial performance of silver–copper–zeolite microparticle-treated organic cotton fabric using versatile methods
Authors: Sk Md Salauddin , Mia Rony , Hoque Ejajul , Ahmed Bulbul , Amin Md Jawad Ibn , Kabir Shekh Md Mamun , Mahmud Sakil
Published: April 2022

Herein, the influence of the antimicrobial treatments of organic cotton fabrics (OCFs) using silver–copper–zeolite microparticles (hereafter referred to as ‘zeolite’) was investigated. There were six different methods applied to six different types of OCFs. The antimicrobial performance demonstrates around 95.33 and 93.88% reductions in gram-positive and gram-negative bacteria after 30 times home laundry, respectively. The surface plasmon resonance of color stability meets the commercial requirements with colorfastness ratings of 3–4 for wash, 4 for light, 4–5 for dry rubbing and 3–4 for wet rubbing. These findings established that this treatment successfully endowed OCFs with long-lasting antimicrobial capabilities and thermal stability due to the interaction with the microparticles. The phenomenon was further confirmed by morphological, spectroscopic and thermal characterization. This approach of OCF functionalization avoiding hazardous chemicals could be a benchmark for antimicrobial performance in sustainable industrial applications.
Binary Modernisms: An Introduction
Authors: Nikolova Zlatina
Published: April 2022

Seeking out new approaches to modernist studies, ‘Binary Modernisms’ adopts the digital, both its approaches and its products, for the critical investigation of Modernism. The following introduction briefly touches on the cultural and historical circumstances of both Modernism and the digital and identifies their parallel impact on art and our engagement with it.
Betriebliches Gesundheitsmanagement bei Schlafstörungen
Authors:   Akademie für Schlafmedizin/t&t Organisationsentwicklung, Landau, Weeß Hans-Günter
Published: April 2022

Wer schläft, so die gängige Vorstellung, der arbeitet nicht und ist nicht wettbewerbsfähig. Die Konkurrenz allerdings schläft bekanntlich nicht. Maschinen sind in der Lage, rund um die Uhr zu arbeiten, doch der Mensch zeigt vermeintliche Schwächen und braucht seinen Schlaf. Aus diesem Grunde wurde die Schichtarbeit eingeführt. Aber wie geht man mit den Herausforderungen der Schichtarbeit an einen gesunden Schlaf um?
Betriebsärztliche Schweigepflicht in Zusammenhang mit Impfungen und COVID-19-Testungen im Betrieb (Interview)
Authors:   Institut und Poliklinik für Arbeits-, Sozial- und Umweltmedizin der Friedrich-Alexander-Universität Erlangen-Nürnberg, Schmitz-Spanke Simone
Published: April 2022

Seit kurzem sind die gesetzlichen Corona-Maßnahmen in Unternehmen weggefallen und in die Eigenverantwortung der Unternehmen übergegangen. Gleichzeitig gilt seit Mitte März die gesetzliche Impfflicht für bestimmte Einrichtungen, zum Beispiel im Gesundheitswesen. Auch wenn sich vieles ändert, bleiben die Fragen zur betriebsärztlichen Schweigepflicht auch künftig bestehen und betreffen nicht nur die COVID-19-Impfungen. Zumal man mit einem erneuten Anstieg der Fallzahlen im Herbst durchaus rechnen muss. Donata Gräfin von Kageneck ist Fachanwältin für Medizinrecht und Sozialrecht. Sie hat uns die wichtigsten Fragen zur Schweigepflicht in Zusammenhang mit COVID-19-Impfungen Testungen beantwortet.
Das Frühjahr und die Sommertage nähern sich – die Zecken ebenfalls
Authors:   Department Biologie, Heinrich-Heine-Universität Düsseldorf, Mehlhorn Heinz
Published: April 2022

Im Frühjahr erwachen in Europa allerorten verstärkt Aktivitäten in der Tierwelt – so auch bei den Zecken, die auf Pflanzen lauern, vorbeistreifende Menschen und Tiere befallen und sich dann von deren Blut ernähren. Damit das Blut während des Saugens nicht gerinnt und ihre Mundwerkzeuge dauerhaft verstopft, injizieren sie Speichel, der das Blut flüssig hält – leider aber auch – je nach Land – eventuell lebensbedrohliche Krankheitserreger. Daher ist es wichtig, sich durch Aufsprühen von Repellenzien zu schützen, was meist aber nur wenige Stunden anhält.
Zwischen Flexibilität und Entgrenzung – Arbeits(zeit)organisation bei mobilem Arbeiten
Authors:   Bundesanstalt für Arbeitsschutz und Arbeitsmedizin, Gruppe „Arbeitszeit und Organisation“, Dortmund, Entgelmeier Ines
Published: April 2022

Mit dem Arbeiten von zuhause, unterwegs im Zug oder im Coworking Space flexibilisieren sich nicht nur Orte, an denen Beschäftigte arbeiten, sondern oft auch Arbeitszeiten. Dies kann einerseits mit mehr Freiheit in der Arbeitszeitgestaltung und einer besseren Vereinbarkeit von Beruf- und Privatleben einhergehen. Andererseits können Arbeit und Freizeit gerade bei dem bislang eher weniger geregelten mobilen Arbeiten stärker miteinander verschwimmen, Arbeitszeiten ausgeweitet, Pausen und Erholungszeiten verkürzt werden.
Estimating sanitary sewer pipeline infrastructure from basic characteristics of a service zone
Authors: JM Winter  , C Loubser  , A Bosman
Published: April 2022

The standard design and cost estimation for a sewer network involves considerable time and financial investment. There are, however, many cases where a rapid assessment of the sewer infrastructure or related costs associated with a service zone might be required. Although there are numerous approaches to rapid sewer infrastructure estimation in the literature, to date, no widely available tool has been developed that can be applied to reliably estimate the expected sewer pipeline infrastructure associated with a service zone in South Africa. The aim of this study was to develop a method for estimating the sewer pipeline infrastructure required for a service zone, based on limited information, that could be applied to future developments. A database of South African sewer network data was used in the development of three major study outcomes. Study Outcome I involved developing regression models for estimating the total sewer pipeline length using only basic service zone characteristics. Models were developed for different categories of land use and area size, allowing for estimation of the total pipeline length as a function of the service zone area size, relief, and the density of contributing users. Study Outcome II involved determining the average pipeline diameter distributions for different types of service zones, enabling disaggregation of the total pipeline length into lengths per diameter. Study Outcome III involved determining the average number of manholes per kilometre of sewer pipeline. Combined, the three study outcomes form an infrastructure estimation tool that enables the sewer pipeline length per approximate diameter and the number of manholes associated with a service zone to be estimated, applicable to service zones smaller than 450 hectares. This study illustrates how the same methodology can be followed to develop similar tools which are applicable to other specific regions or development types, provided an appropriate dataset is obtainable.
The impacts of long-term flow reductions and an extreme drought on a large, permanently open estuary, and implications for setting the ecological reserve
Authors: Barry M Clark  , Jane K Turpie  , James DS Cullis  , Jessica Dawson  , Louise Dobinson  , Marlé M Kunneke  , Annabel Horn
Published: April 2022

Environmental water requirements (EWRs) are set for South Africa’s estuaries to ensure that they are maintained in a state that is both achievable and commensurate with their level of conservation and economic importance.  However, these EWRs are typically determined on the basis of models and scenario analyses that require extrapolation beyond existing data and experience, especially if climate change is considered.  In the case of the Berg Estuary, South Africa, available data on changes in freshwater flow and water quality span a period of at least five decades (1970s–present) during which significant reduction in flows has been observed.  Monitoring data also cover an extreme 3-year drought, from 2015−2017, which provided a unique opportunity to study the effects of severe freshwater starvation (zero-flow for an extended period) on this large, permanently open system.  Our analyses show that mean annual runoff (MAR) under present-day conditions has been reduced to around 50% of that under reference (natural) conditions and that reduction in runoff during the low-flow season (summer) has been more severe (80–86% reduction) than for the high-flow season (39–42% reduction).  The salinity gradient now extends much further upstream than under reference conditions.  Hypersaline conditions along with a reverse salinity gradient were recorded in the estuary for the first time ever during the drought of 2015/17.  Levels of dissolved inorganic nitrogen (NOx) reaching the estuary from the catchment have increased dramatically (6–7 fold) over the past five decades, dissolved reactive phosphate (PO4) slightly less so (2–3 fold), but ammonia (NH4) hardly at all.  Increases in nutrient input from the catchment in the high-flow season are also much more dramatic than in the low-flow season.  The estuary is no longer compliant with gazetted EWRs and requires urgent interventions to restore the quantity and quality of freshwater it receives.
Inequity in insurance coverage for prescription drugs in New Brunswick, Canada
Authors: Ayodele Busola , Guo Elaine Xiaoyu , Sweetman Arthur , Guindon G. Emmanuel
Published: April 2022

Objectives

To describe the extent to which New Brunswick residents reported having drug insurance coverage supplementary to Canadian Medicare; to examine associations between socioeconomic and demographic characteristics, health status, language identity, and having reported such coverage; and to document any changes in coverage associated with the introduction of the New Brunswick Drug Plan in 2014.

Methods

We used repeated cross-sectional data for New Brunswick from eight cycles of the Canadian Community Health Survey from 2007 to 2017 and undertook logistic regression analysis.

Results

We found statistically significant, substantial and policy-relevant socioeconomic differences in the reporting of prescription drug insurance coverage among those 25–64 years and those ≥ 65 years of age, and an increasing reliance on private drug insurance over time. We found that individuals in the second decile of household income were particularly vulnerable to reporting neither public nor private drug coverage. The introduction of the New Brunswick Drug Plan in 2014 does not appear to have led to increased public drug coverage; however, from 2014, the decreasing trend in public drug coverage appears to have ceased. Those who reported lower health status usually had lower odds of reporting private drug coverage but higher odds of reporting public drug coverage. Driven by differences in private coverage, we found that relative to anglophones, francophones were less likely to report any drug coverage.

Conclusion

Our findings emphasize the shortcomings of drug insurance systems such as that introduced in New Brunswick and substantiate calls for a universal drug program. New Brunswick’s increasing reliance on private drug insurance is of concern and warrants additional research.
Avrupa Birliği ve Türkiye’de Genç Yoksulluğu
Authors: ERİKLİ Suheyla
Published: April 2022

Bu çalışmanın amacı genç yoksulluğunu Avrupa Birliği üyesi on bir ülke ve Türkiye açısından değerlendirmektir. Bu amaçla Avrupa İstatistik Ofisi’nin (Eurostat) gençlere yönelik sosyal içerme verileri ve yoksulluk verileri kullanılmıştır. Çalışmada öncelikle yoksulluk ve genç yoksulluğu kavramları tanımlanmış; daha sonra Bulgaristan, Almanya, Yunanistan, İspanya, Fransa, İtalya, Avusturya, İsveç, Birleşik Krallık, İsviçre, Norveç, Finlandiya ve Türkiye’de 16-29 yaş arası gençlerin yoksulluk riski ve sosyal dışlanma durumu (yoksulluk riski, aşırı materyal yoksunluk ve çok düşük iş yoğunluğuna sahip ailelerde yaşayan gençlerin yoksulluk riski) ve ayrıca aile ile yaşama durumuna göre yoksulluk riski ve çalışan gençlerin yoksulluk riski incelenmiştir. Araştırma sonucunda gerek incelenen ülkelerde gerekse Türkiye’de yıllar içerisinde genç yoksulluk riskinin düşme eğilimi göstermesine rağmen hala önemli düzeyde yüksek olduğu belirlenmiştir. Ülkeler cinsiyet açısından incelendiğinde genç kadınlarda genç erkeklere göre yoksulluk riski daha yüksek olduğu görülmektedir.
Dijital Oyunlarda Transmedya Hikâyeciliği: Assassin's Creed Serisi Örneği
Authors: SÖĞÜT Fatih
Published: April 2022

Yeni medya ortamlarının gelişmesi ve Web 2.0'ın ortaya çıkışı, kullanıcıların rollerinde köklü değişikliklere yol açmıştır. Bu değişiklikler tüketicileri sadece tüketen pasif kitlelerden üreten ve katılımcı bireyler haline getirdi. Yeni medya ortamlarının yakınsamaya ve katılımcılığa dayalı yönü kullanıcıları kültürel üretime ortak haline getirmiştir. 2000’li yıllarda dijital ortamlarda hikâye anlatma sanatı transmedya hikâyeciliği kavramı ile tanıştı. Transmedya hikâyeciliği bir hikâyenin farklı bölümlerini farklı platformlardan o platformlara özgü bir biçimde sunmak olarak açıklanabilir. Bu çalışma ile amaçlanan bütün dünyada önemli bir hayran kitlesine sahip Assassin's Creed serisinin transmedya hikâyeciliği özelliklerine sahip olup olmadığını incelemektedir. Bu araştırmada Metin analizi yöntemi kullanılmıştır. Araştırma sonuçlarına göre Assassin’s Creed serisi bir transmedya projesi olarak başlamamıştır. Ancak birkaç oyun ve bağlantılı medya metinleriyle transmedya anlatısı haline gelmiştir.
Cerebral Venous Thrombosis without Thrombocytopenia after COVID-19 Vaccination
Authors: Hwang Jeongsu , Sohn Jong-Hee , Lee Sang-Hwa , Lee Eungue , Jeon Wonseok , Kim Yerim
Published: April 2022

Cerebral venous thrombosis (CVT) is a rare form of cerebrovascular attack and its predisposing factors commonly co-exist. In the coronavirus disease 2019 (COVID-19) era, various side effects of COVID-19 vaccine have been reported, and CVT is one of the well-known types. It is usually explained as prothrombotic immune thrombocytopenia by an antibody binding to platelet factor 4 receptor. However, some cases are irrelevant to thrombocytopenia and calls for a new explanation. Here we report a case of CVT without thrombocytopenia after COVID-19 vaccination.
Transient Mutism Related to Capecitabine-Induced Acute Toxic Leukoencephalopathy
Authors: Kim Hyung Ho , Kim Hyunji , Kim Sumin , Kim Soo-Hyun , Kim Geon Ha
Published: April 2022

Capecitabine, a precursor of 5-fluorouracil (5-FU), is a well-tolerated and safe chemotherapy that has been used to treat breast, pancreatic, and colorectal cancers. Albeit rare, both 5-FU and capecitbine have been reported to be associated with acute central nervous system toxicity, including cerebellar dysfunction, posterior reversible encephalopathy syndrome, and transient leukoencephalopathies. Here we present a case of 32-year-old female, demonstrating transient mutism related to capecitabine induced acute toxic leukoencephalopathy.
Recurrent Cerebral Infarction Associated with Uterine Adenomyosis
Authors: Park Ki-Seok , Ahn Sung-Ho , Park Min-Gyu , Park Kyung-Pil
Published: April 2022

Uterine adenomyosis, which is known as a benign gynecological disease, can induce hypercoagulable state and be an uncommon cause of cerebral thromboembolism, as cerebral infarction is common in patients with malignant neoplasm. We report a woman with uterine adenomyosis who shows several episodes of cerebral infarction and discuss the stoke mechanism and treatment of this under-recognized etiology of stroke.
An Autoimmune Encephalitis Case Associated with Pembrolizumab Use
Authors: Yum Jung Yon , Kim Joonho , Kim Taewon , Park Woo Hyun , Chu Min Kyung
Published: April 2022

Immune checkpoint inhibitors may be associated with various adverse events, including encephalitis. Here, we report a case of encephalopathy associated with pembrolizumab therapy. A 60-year-old male diagnosed with cholangiocarcinoma with peritoneal seeding presented altered mentality and cognitive function after using pembrolizumab. Electroencephalogram showed mild diffuse cerebral dysfunction. Cerebrospinal fluid (CSF) study showed no evidence of infection or autoimmune disease and no paraneoplastic antibody was detected from CSF and serum. After high-dose methylprednisolone intravenous infusion, patient’s mentality was fully recovered.
Garcinia Cambogia-Induced Refractory Status Epilepticus
Authors: Nam Hyun-wook , Kim Keun-Tae , Song Minji , Kim Hayom , Kim Jung Bin
Published: April 2022

Garcinia cambogia (G.cambogia) is a herbal dietary supplement for managing obesity. Several adverse effects of G.cambogia have been reported including serotonin syndrome and mania. We report a patient with refractory status epilepticus after taking G.cambogia. A 24-year-old woman was admitted with continuing seizures. Based on electroencephalography and neuroimaging findings, she was diagnosed as refractory status epilepticus attributed to G.cambogia-related encephalopathy. After cessation of the G.cambogia with administrating antiepileptic drugs, she fully recovered without seizure recurrence and neurological sequelae.
Overview of scRNA-seq of Human Knee Articular Cartilage v1
Authors: not provided molmer , Lotz Martin
Published: April 2022

The overview provides sub-protocols for each step required to complete scRNA-seq from human knee articular cartilage.
[RETRACTED] Laura Ingraham CBD Gummies v1
Authors: not provided wailmilsh
Published: April 2022

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[RETRACTED] Eagle Hemp CBD Gummies Reviews -How Dose It Works? v1
Authors: Hemp CBD Eagle
Published: April 2022

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[RETRACTED] Bernard Pivot CBD Gummies 2022 – Does it Really Work? v1
Authors: not provided BernardPivotCBDGummies
Published: April 2022

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Are you searching for a CBD oil consumption in your eating routine that will assist you with feeling improved?
[RETRACTED] Keto Maxx Pills Reviews - Is It Fake Or Trusted Shark Tank Pills? v1
Authors: not provided ketomaxxpillsreviews
Published: April 2022

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[RETRACTED] Tetrogen! Tetrogen Weight Loss! {Weight Issues Vanished} Naturally Designed Formula For Fit Body! v1
Authors: not provided jaqesperro
Published: April 2022

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[RETRACTED] Keto Prime Real reviews - How does it works? v1
Authors: not provided ketoprimeealreviews
Published: April 2022

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CODEX Staining Protocol For FFPE Tissue v1
Authors: J Ahn Kyung , Bandyopadhyay Shovik , Thadi Anusha , Tan Kai
Published: April 2022

This protocol describes the method for antibody staining of FFPE tissues on coverslips using CODEX Barcoded Antibodies. The Akoya CODEX user manual was modified to include photobleaching steps. Included are the stepwise protocols for pre-staining, deparaffinization, antigen retrieval, photobleaching, antibody staining and post-fixation.
On Ground States for the SOS Model with Competing Interactions
Authors:   Institute of Mathematics Academy of Sciences of Uzbekistan, Rahmatullaev Muzaffar M.
Published: April 2022

We study periodic and weakly periodic ground states for the SOS model with competing interactions on the Cayley tree of order two and three. Further, we study non periodic ground states for the SOS model with competing interactions on the Cayley tree of order two
An Analogue of the Hartogs Lemma for R-Analytic Functions
Authors:   V. I. Romanovsky Institute of Mathematics, Atamuratov Alimardon A.
Published: April 2022

The paper is devoted to the problem of R-analytic continuation of functions of several real variables which admit R-analytic continuation along parallel sections. We prove an analogue of the well-known Hartogs lemma for R-analytic functions
On the Cauchy Problem for the Biharmonic Equation
Authors:   Samarkand State University, Shodiev Dilshod S.
Published: April 2022

The work is devoted to the study of continuation and stability estimation of the solution of the Cauchy problem for the biharmonic equation in the domain G from its known values on the smooth part of the boundary @G. The problem under consideration belongs to the problems of mathematical physics in which there is no continuous dependence of solutions on the initial data. In this work, using the Carleman function, not only the biharmonic function itself, but also its derivatives are restored from the Cauchy data on a part of the boundary of the region. The stability estimates for the solution of the Cauchy problem in the classical sense are obtained
A Problem with Wear Involving Thermo-Electro-viscoelastic Materials
Authors:   Faculty of Sciences Ferhat Abbas University of Setif-1 Setif, Bachmar Aziza
Published: April 2022

In this paper, we consider a mathematical model of a contact problem in thermo-electro- viscoelasticity. The body is in contact with an obstacle. The contact is frictional and bilateral with a moving rigid foundation which results in the wear of the contacting surface. We establish a variational formulation for the model and we prove the existence of a unique weak solution to the problem. The proof is based on a classical existence and uniqueness result on parabolic inequalities, differential equations and fixed point arguments. We present a variational formulation of the problem, and we prove the existence and uniqueness of the weak solution
Effect of Thermopriming and Alpha-Tocopherol Spray in Triticum aestivum L. under Induced Drought Stress: A Future Perspective of Climate Change in the Region
Authors: Shakir Ubaid Ullah , Ullah Sami , Muhammad Nauman Khan Muhammad Nauman Khan , Ali Sajjad , Ali Usman , Zaman Akhtar , Abdul Razak Sarah , Ahmet Ozdemir Fethi
Published: April 2022

Because of global warming and decreased river flows, all of Pakistan's provinces, especially large parts of Sind and Baluchistan, have been experiencing water shortages for decades. Based on such climatic changes several management techniques have been recommended to cope through drought stress. This study is focused on the assumption that seed soaking of Triticum aestivumL. at low (4 °C) and high (80 °C) temperature (thermopriming) with exogenous spray of alpha-Tocopherol (150 mol/L) will increase seedling formation and crop production through drought stress of 5 and 10 days recommended to persuade resistivity in test species. This study also describes resistance mechanism of drought both in physiological and biochemical activities. Results concluded that chlorophyll a & b, carotenoids, sugar, protein and proline (µmg/g) contents were detected maximum in case of T1 (control) and T5 (5 days drought + 4 °C + α-Tocopherol) enhancing growth and osmolytes component in plant whereas; antioxidant enzymes bitterly respond under induced high drought stress and growth regulator at p≤0.05. The study showed the degree of resistance to various drought stressors best suited in agricultural country (Pakistan) signifying successful demonstration of priming method with the application of α-Tocopherol as growth regulator will help agricultural industries improve seed quality and germination rate.
Laboratoty Experiment on Copper and Lead Adsorption Ability of Microplastics
Authors: Goh Patricia Blair , Pradit Siriporn , Towatana Prawit , Khokkiatiwong Somkiat , Ong Meng Chuan
Published: April 2022

The persistent presence of microplastics in the marine environment has become a major threat to many marine organisms and this issue continues with heavy metals pollution. Microplastics and heavy metals are commonly categorized in different type of pollutant group and the understanding of interlinkage between these two contaminants is less discovered. During 7 days laboratory controlled experimentation, we examined the heavy metals; copper (Cu) and lead (Pb) adsorption ability of microplastics fragment derived from plastic straws and plastic grocery bags. We found that both microplastic types adsorbed the two heavy metals through exposure to Cu and Pb spiked seawater with different concentrations, respectively. The adsorption kinetics was represented using partition coefficients that resulted in coefficients between the microplastic fragments and water ranged between 5 and 28 for Cu on plastic straws and bags fragment; 3 and 35 for Pb. The adsorption of Cu and Pb both was significantly higher in plastic bag micro fragments, probably due to higher surface area and polarity. Throughout the experiments time expansion, the concentrations of Cu and Pb significantly increased on both microplastic types. The results of consequential interaction between the selected microplastics and heavy metals strongly support the condition of microplastic ability to adsorb heavy metals and act as a vector for heavy metal ions distribution in the marine ecosystem.
Chemical Constituents and Anti-Neuroblastoma Activity from Boesenbergia stenophylla
Authors: Primus Phoebe Sussana , Ismail Muhammad Hazran , Adnan Nabila Elyana , Wu Carol Hsin-Yi , Kao Chao-Lin , Choo Yeun-Mun
Published: April 2022

Three diarylheptanoids and one flavonoid, i.e. 7-(4-hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one (4), 5R-hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-phenylheptan-3-one (5), 1,7-diphenylhept-4-en-3-one (6), and 3,5,7-trihydroxyflavone (7) were isolated and characterized from the rhizome of Boesenbergia stenophylla. Compounds 2 and 4 displayed excellent anti-neuroblastoma activity which reduces the cell viability to 30% and 20%, respectively. The results from the molecular docking experiments targeting the protein kinases regulating neuroblastoma cell survival (PI3K/AKT1 signalling pathway) are consistent with that of the in vitro results. Finally, the structures of 4-7 were elucidated using spectroscopic methods (UV, IR, NMR, and HRESIMS).
Optimum Extraction Condition of Anacardium occidentale on Antiurolithiatic Activities (in-vitro)
Authors: Abdul Rahim Nur Fazira , Muhammad Norhayati , Abdullah Norazlin
Published: April 2022

Urolithiasis or kidney stone has become a worldwide problem including Malaysia. Its management is depending on surgical procedures that are quite costly and can cause reoccurrence. Anacardium occidentale (cashew) has been used traditionally to treat urolithiasis but no scientific data has been recorded that proven its efficiency particularly on its extraction parameters. Therefore, this study aims to identify the optimum extraction parameters of A. occidentale leaves extracts on in-vitro antiurolithiatic activities using Response Surface Methodology (RSM). The effect of three extraction parameters (solvent concentration, X1; extraction temperature, X2; extraction time, X3) on antiurolithiatic activities (turbidity or nucleation assay, Y1; titrimetric or calcium oxalate dissolution assay, Y2) were determined by Central Composite Design (CCD). The results showed that each parameter and its interaction significantly affect the antiurolithiatic activities (p < 0.05). The quadratic model was closely fitted for all responses as the R2 values obtained were 0.9786 (turbidity assay) and 0.9956 (titrimetric assay). The optimum extraction condition of A. occidentale leaves extract suggested by the predicted model was at 0.4% ethanol concentration, temperature 31.5 ℃ and for 30 min of extraction time, exhibited antiurolithiatic activities of 85.57 ± 0.43% (turbidity) and 96.48 ± 0.70% (titrimetric). The phytochemical screening was done on the presence of phenols, tannins, flavonoids, alkaloids, saponins as well as terpernoids and all phytochemicals were identified in the optimized A. occidentale leaves extract. This study has given basic scientific evidence that optimum extraction conditions are necessary to obtain optimum antiurolithiatic activity.
Drug-Herb Interactions: Selected Antihypertensive Drugs with Moringa oleifera Leaves Extract
Authors: Kumolosasi Endang , Cheong Mandy Li Ching , Ahmad Salwanizam Nuraina Athira , Muhammad Esham Nur Shamizah Ainna , Ayob Qistina Alyani , Ramasamy Ramavisithira , Govindan Harishankari , Md Redzuan Adyani , Jasamai Malina
Published: April 2022

Moringa oleifera is a local plant which is commonly used in cooking and as a health supplement. It has been reported to possess blood pressure (BP) lowering effect and little is known about its possible interactions with cardiovascular drugs. This study looked into the possible drug-herb interactions between M. oleifera leaves extract and selected antihypertensive drugs. Ten groups of spontaneously hypertensive rats (SHRs) and one group of normotensive rats (NTs) were administered either M. oleifera extract alone, drugs alone or drugs in combination with M. oleifera extract for 14 days and BP of the rats were measured. Angiotensin converting enzyme (ACE) activity was also determined in vitro and ex vivo. Treated groups were found to produce significant BP reduction on day 15 when compared with the negative control but there was no significance difference when compared with positive controls (drugs alone). M. oleifera extract administered alone significantly reduced BP of SHRs on day 15 and this is comparable with the BP reduction observed when antihypertensive drugs were administered alone. However, no additive effect was observed when drugs were used in combination with M. oleifera extract. Similar results were seen in the in vitro and ex vivo ACE inhibitory activity of M. oleifera extract and enalapril. It can be concluded that there is a possibility of drug-herb interaction between M. oleifera extract and the selected antihypertensive drugs.
Masculinidad, Feminidad y Sexualidad En Las Dos Orillas Del Mediterráneo: Los Discursos De Varones Españoles Y Marroquíes
Authors: Carrión López Antonia María
Published: April 2022

El género, la masculinidad y la feminidad, son construcciones sociales y, por lo tanto, conceptos dinámicos, cambiantes, influenciados por las circunstancias específicas de cada contexto cultural. En tanto que concepto binario, el género no sólo determina las formas de ser hombre y mujer, sino también las maneras en las que hombres y mujeres deben relacionarse. El objetivo de este artículo es analizar la concepción que los varones marroquíes y españoles tienen sobre la masculinidad y la feminidad, así como la relación de éstas con las formas de entender la sexualidad en ambas culturas.  A través del análisis del discurso social reproducido por los 24 hombres participantes en un total de 5 grupos de discusión realizados en España (2) y Marruecos (3), el artículo presenta cómo las concepciones de masculinidad y feminidad responden a una esencia común, fundamentada en estereotipos similares, pero modificada por las características específicas de cada uno de los contextos de estudio. Las diferentes concepciones de la sexualidad en cada uno de los contextos, así como la evolución de las mismas, sería unos de los elementos clave que explican las diferencias entre los estereotipos y relaciones de género en ambos países.
Ideología de Roles Sexuales de Estudiantes en una Facultad de Ingeniería Colombiana
Authors: Vázquez-Miraz Pedro , Medina Reyes María Fernanda , Pastrana Quintana Camilo Andrés , Rincón Socha María Eugenia
Published: April 2022

En el presente escrito se examinaron las percepciones que tenían estudiantes de diferentes programas de ingeniería de una universidad privada de Cartagena de Indias (N = 243) con el objetivo de identificar de manera nítida el perfil de un ingeniero en formación con una ideología de los roles sexuales de corte tradicionalista, pues históricamente se ha asumido este ámbito educativo como algo masculino. Por medio de un estudio descriptivo de corte transversal y basándonos en las variables predictoras sexo, edad y programa académico se identificaron diferencias significativas en las dos primeras (valores más sexistas en hombres y personas de mayor edad), más al haber introducido un cálculo univariante, el modelo que incorporó las tres variables también fue significativo. Por ende, se ha reconocido que ciertas carreras (como las Ingenierías Eléctrica y Electrónica) han presentado de modo constante diferentes puntuaciones asociadas a una visión conservadora en relación con los roles de los hombres y las mujeres.
The Images of Man in Indonesian Literature
Authors: Ahmadi Anas
Published: April 2022

The research aims to describe masculinities contained in two Indonesian novels, Orang-orang Biasa and Rafilus. Specifically, the aims are divided into 2, namely (1) how the characters’ behaviors that are represented in the Orang-orang Biasa and Rafilus reviewed from the psychology of masculinities perspective are, and (2) how the impacts of characters’ behaviors on other people represented in the Orang-orang Biasa and Rafilus reviewed from the psychology of masculinities perspective. The theory used in this research was the psychology of masculinities which was related to the psychology of literature. The method used was descriptive qualitative which focused on narrative data exposure. The data collection technique used was a literature review. The data analysis technique was conducted with several steps, namely identifying the data, classifying the data, reducing the data, interpreting the data, describing the data, and verifying the data. The results showed that man's behaviors are represented in several forms. First, the men who have healthy behaviors are the ones who are strong, responsible, and honest. Second, the men who have unhealthy behaviors are the ones that have toxic masculinities which are represented in their behaviors that tend to hurt others and commit crimes.
Концепция искусства био-арта в культуре постиндустриального общества
Authors:   Санкт-Петербургский государственный институт культуры, Лопаткина М.А.
Published: April 2022

Статья посвящена начавшимся в биологических науках изменениям, связанных с перестройкой сознания человечества, выступая предпосылкой зарождения интереса к освоению био-арт практик. Представления о природе жизни всё больше биологизируются, и это является расхождением с первоначальной истиной, формируя постепенно представление о теле как о технологии, инструменте выражения и моделирования. Поэтому в связи с ограничением человеческой свободы сознания и, вследствие чего, телесности, необходимо найти пути переосмысления привычных форм реальности. Художники био-арта выступают за идею возникшего предельного развития естественной эволюции человечества. В исследовании анализируется практика био-арта, обозначенная Эруардо Кацем в 1997 году. Актуальность исследования состоит в стремлении найти способы перманентного контроля за собственным телом благодаря био-арт практикам. Выступая как синтез между биологией и искусством, они направлены на модернизацию телесности, главным образом, телесности человека, а именно, что для достижения новой ступени эволюции, человеку необходимо отказаться от своей привычной оболочки в пользу модификационного киборга. Теоретики и художники, исследовавшие тело в искусстве и био-арте, отмечают, что «био-искусство не создаёт объекты, события или виртуальные образы — оно управляет онто- и филогенезом». Это направление становится «новой школой искусства», где будут пересекаться два направления, использующие традиционные техники (фотографию, скульптуру, живопись) и произведения, созданные с использованием биологических феноменов. Ученые проводят манипуляции с биологическими материалами организма в симбиозе с техническими методами. Их исследования направлены на легкое точечное видоизменение молекулярных структур с помощью нанотехнологий, компиляцию уже существующих частиц и искусственный рост новых объектов. Био-арт использует различные практики интерпретаций — живопись, скульптуру, перфомансы, боди-арт практики, методы концептуального искусства, помимо взаимосвязи биологии, техники и искусства, сформировав решение главной задачи — создание инновационного живого будущего, которое полностью можно держать под контролем человека, нивелируя механические функции. Научная новизна работы заключается в проведении исследования, показывающего как искусство био-арта вписывается в методы постиндустриализации на примере работ ведущих представителей био-арта, придавая искусству, главным образом, человекообразующую роль.
Дизайн логотипа как основа культуры фирменного стиля. Его функции и основные элементы
Authors:   Санкт-Петербургский государственный университет промышленных технологий и дизайна, Степанова Степанова
Published: April 2022

Данная статья как результат исследовательского процесса, создана на основе личного опыта. Цель исследования — выявление коммуникативно-визуальных особенностей типографики дизайна логотипа. Она будет интересна обучающимся, студентам художественных направлений по специальностям графический дизайнер и веб-дизайнер. Статья раскрывает понятие «фирменный стиль», посвящая в разнообразие его элементов: фирменный знак, шрифт, цвет. Основываясь на предыдущих исследованиях, в статье обобщены теоретические подходы к понятию логотипа; приводятся наиболее яркие примеры существующих наработок в этой области. Описываются средства дизайна логотипа, приводятся методы разработки. Представлены основные виды логотипов, их классификация по типам исполнения. Так же в статье поясняется такое современное понятие, как айдентика, и чем она отличается от фирменного стиля, с которым часто её путают. Данное исследование имеет практический характер, и содержит советы, которые помогут при взаимодействии с реальным заказчиком.
The Use of Social Media by Spanish Feminist Organizations: Collectivity From Individualism
Authors: Navarro Celina , Gómez-Bernal Gemma
Published: April 2022

In recent years, social media platforms have become a popular tool for feminist activists and the main medium of communication for new feminist organizations to gain higher visibility. However, along with opportunities, they also bring a reshaping of communication forms and challenges in the modes of organization of these groups, which seek to transform the prevailing individualist logic of the mediated social media landscape into a collective identity. Through the findings of qualitative, semi-structured interviews and the analysis of the content published online, this article looks at the structures of interactions and organizing processes in the social media accounts of new Spanish feminist groups. The findings show that although the committees are aware of the importance of an online presence, they face many obstacles in the creation of collective profiles due to the lack of guidelines, having no clear organized steps on how to post content with consensus within each committee, and the many demands of the speed-driven nature of social media platforms.
A Digital Controller as a Subject of Public Financial Control
Authors: Antroptseva I. O.
Published: April 2022

The relevance of the study of the concept of a digital controller is predetermined by an active introduction of digital technologies into the control and supervisory activities of authorized bodies, which is expressed in the development of new technologies, the use of automated systems, artificial intelligence and other achievements. The use of digital technologies of various levels of complexity (gradually being introduced, breakthrough technologies and technologies of the near future) to increase the efficiency of the activities of control and supervisory authorities forms a new type of public financial control — digital public financial control that has a number of features, and, accordingly, is carried out by a specific entity. The entity exercising digital public financial control has new characteristics. The term a “digital controller” is new, there is no legal definition of it in the current legislation of the Russian Federation. Plans for the introduction of new digital technologies, especially artificial intelligence and robots, lead to discussions about their role in the legal relations that develop with their participation, that is, they lead to the development and analysis of the problem of attributing them either to objects or subjects. Thus, it seems appropriate to study the concept of “digital controller”, as well as its place in control and supervisory legal relations. At the present stage of development, we can confidently talk about the possibility of considering a digital controller in three aspects: as a control and supervisory authority, which is the subject of digital public financial control; employees of control and supervisory authorities working directly with digital systems; electronic persons, that is, artificial intelligence and robots as independent subjects.
Judicial Control over Compliance with Plea Agreement at Special Stages of Criminal Procedure
Authors: Stekolnikov D. V.
Published: April 2022

The paper discusses the extension of judicial control at the special stages of a criminal procedure in case the defendant violates the plea agreement being a cassation and supervisory basis for the cancellation of the verdict that has entered into legal force. The author reveals obvious conceptual and legal-technical contradictions of the mentioned ground for the current procedural forms of criminal cassation and supervision and the resulting inability of the relevant verification stages to implement the problematic ground. In addition to the instrumental errors of the considered grounds for reversing the judgment that has entered into force, attention is drawn to its contradictions with the European standards of res judicata and non bis in idem in the sense given by the law enforcement practice of the European Court of Human Rights. The author proposes options for resolving the identified problems, filling the uncertainty of legal regulation by referring to the institutions of criminal and criminal procedural law. In order to achieve the aims related to the control over conscientious fulfillment of the terms of a plea agreement set by the legislator, it is proposed to consider the violation of such an agreement by the defender as a newly discovered circumstance. This option will optimize the procedural order of proceedings on court decisions that have entered into legal force, keep it away from technical and conceptual contradictions, and ensure the proper fulfillment of its international legal obligations by the Russian Federation.
Dualism in the Institution of Marriage Regulation System in the State of Israel
Authors: Liviev N. M.
Published: April 2022

The paper discusses one of the most interesting institutions of Israeli family law, namely, the institution of judicial dissolution of marriage. The specificity of this institution lies in the fact that divorce proceedings are carried out by religious courts that have been operating for more than one century. In the State of Israel, along with the system of religious courts, a special, non-denominational court of general jurisdiction, called the Family Court, has been established and operated. The jurisdiction of this Court includes consideration and resolution of issues related to guardianship of minors and incapacitated individuals, that is, all those cases that arise as a result of the dissolution of marriage. At the same time, the issues of confirming the existence of marital relations and their termination are assigned to the exclusive jurisdiction of religious courts. If the spouses, by their religion, belong to Judaism or Islam, dissolution of a marriage is only possible by a decision of a religious court. The dissolution of a marriage between spouses belonging to Christianity is carried out in the general civil Family Court that operates under a specially developed law with respect to cases that are deemed special for Israel. Family matters, including the dissolution of marriages, in the Druze religious community are dealt with by a special judicial instance, the Druze court that differs from the courts of general jurisdiction.
Atypical fracture of the femur in a patient with postmenopausal osteoporosis after four injections of zoledronic acid
Authors: Gladkova Elena N. , Lesnyak Olga M.
Published: April 2022

Bisphosphonates are one of the most effective medications widely used in the treatment of osteoporosis. In the last 15 years, descriptions, and observations of unusual low-energy femoral fractures with atypical localization for osteoporosis after prolonged use of these drugs have been published.
A 78-year-old patient applied to the osteoporosis center. She received parenteral bisphosphonate therapy for severe osteoporosis for 4 years. In 2017, a spontaneous fracture of the middle third of the femoral shaft was registered (the fracture occurred while walking). Regarding the fracture, metal osteosynthesis with a plate was performed. Subsequently, there was a delayed consolidation of the fracture with the formation of a false joint and the need for repeated surgical intervention. Examination of the patient revealed vitamin D deficiency, and significant negative trend in densitometry.
A feature of this case is poor fracture consolidation and long-term uncompensated vitamin D deficiency. Physicians should be aware of this rare but serious complication of bisphosphonate therapy, as it requires discontinuation of antiresorptive drugs and the appointment of bone anabolic therapy for osteoporosis, which, in addition to treating the underlying disease, also promotes consolidation fracture.