bluuebunny/crossref_metadata_2025 huggingface dataset:
CRITERIA AND PERFORMANCE INDICATORS ACCESSORY COMMUNICATION AS A LEGAL MEANS
Authors: Трухан Роман Петрович
Published: October 2024

В работе рассматриваются проблемы определения эффективности применения акцессорной связи в качестве правового средства, связанные со сложностью определения критериев и показателей ее эффективности. Сделан вывод о необходимости различения критериев и показателей эффективности, показаны особенности их определения в целях установления эффективности акцессорных связей.

The paper examines the problems of determining the effectiveness of using accessory communication as a legal means, associated with the complexity of determining the criteria and indicators of its effectiveness. A conclusion is drawn about the need to distinguish between criteria and indicators of effectiveness, and the features of their definition are shown in order to establish the effectiveness of accessory connections.
СРАВНИТЕЛЬНЫЙ АНАЛИЗ МЕТОДОВ МАШИННОГО ОБУЧЕНИЯ ДЛЯ МОДЕЛИРОВАНИЯ НОВОСТНОГО КОНТЕНТА
Authors: Антонов А.В.
Published: October 2024

В статье анализируются методы машинного обучения для моделирования новостного контента, проводится сравнительный анализ подходов и демонстрируются примеры их успешного применения. Моделирование новостей является ключевой задачей в информационном дискурсе, и сравнение алгоритмов может улучшить автоматическую классификацию и анализ контента
INTEGRATIVE APPROACH TO COSMETOLOGY AND AESTHETIC MEDICINE
Authors: Кюршева Екатерина Александровна
Published: October 2024

Данная статья посвящена интегративному подходу в косметологии и эстетической медицине. В статье дан сравнительный анализ данных до эксперимента и после проведения эксперимента группы людей. Методика, по которой проводилось исследование, имеет название САН (самочувствие, активность, настроение). Эксперимент представлен шкалой, состоящей из индексов (3 2 1 0 1 2 3). Каждый испытуемый выбирает цифру, которая наиболее соответствует его состоянию в конкретный момент времени.

This article is devoted to human psychosomatics, which affects the internal state of a person and his external state. The article provides a comparative analysis of data before the experiment and after the experiment of a group of people. The methodology used to conduct the study is called SAM (well-being, activity, mood). The experiment is represented by a scale consisting of indices (3 2 1 0 1 2 3). Each subject must choose the number that best corresponds to his state at a particular point in time.
НЕИЗВЕСТНЫЕ ПИСЬМА В.А. ГОРДЛЕВСКОГО АКАДЕМИКУ В.В. БАРТОЛЬДУ ИЗ ФОНДА САНКТ-ПЕТЕРБУРГСКОГО ФИЛИАЛА АРХИВА РАН (К 300-ЛЕТИЮ РАН)
Authors: Лю Л. , Валеев Р.М. , Валеев Р.М. , Валеева Р.З. , Кириллина С.А.
Published: October 2024

Академики-востоковеды РАН В.В. Бартольд (член-корр. с 1910 г. и академик с 1913 г.) и В.А. Гордлевский (член-корр. с 1929 г. и академик АН СССР с 1946 г.) – значимые фигуры в истории отечественной классической ориенталистики и арабо-мусульманских штудий, в частности, санкт-петербургского и московского центров востоковедения, особенно в сфере академической и университетской тюркологии, османистики, арабистики, иранистики и общественной жизни Российской империи и СССР. Они широко известны в истории гуманитарной науки современной Российской Федерации и стран СНГ. Основное внимание в данной статье уделено краткому обзору 27 писем В.А. Гордлевского академику В.В. Бартольду (1910 – 1928 гг.) из Москвы, Уфы и Зушы, отразивших этапы его жизнедеятельности и творчества и страницы истории московского востоковедения
ПРОБЛЕМЫ РОДИТЕЛЕЙ И ДЕТЕЙ: ВОПРОСЫ СОХРАНЕНИЯ СЕМЕЙНЫХ ЦЕННОСТЕЙ
Authors: Акматова А.Т.
Published: October 2024

В статье рассматриваются актуальные проблемы, связанные с взаимоотношениями между родителями и детьми в контексте современных вызовов, стоящих перед институтом семьи. Анализируется влияние социальных, экономических и культурных факторов на формирование и сохранение семейных ценностей. Особое внимание уделяется вопросам отчуждения между поколениями, изменениям в семейных ролях и моделям воспитания, а также последствиям для психоэмоционального благополучия детей и подростков. В статье обсуждаются возможные подходы и меры, направленные на укрепление связи между отцами и детьми, поддержание традиционных семейных ценностей и преодоление конфликтов внутри семьи. Предложены практические рекомендации для родителей и специалистов в области семейной психологии, направленные на улучшение внутрисемейного взаимодействия и повышение качества воспитательного процесса.
Взаимодействие высших учебных заведений и органов власти в подготовке государственных и муниципальных служащих: проблемы и перспективы
Authors: Плешивцев А.В.
Published: October 2024

Профессионализм и компетентность будущих государственных и муниципальных служащих во многом определяется эффективностью взаимодействия высших учебных заведений с органами власти и является важным условием качественной практической подготовки управленцев. Однако, как показывает опыт последних лет, уровень и качество данного взаимодействия не в полной мере способствует формированию профессиональных компетенций будущих служащих государственного и муниципального управления. В данной работе анализируются проблемы и предлагаются меры по совершенствованию взаимодействия учреждений высшего образования с органами власти в сфере подготовки бакалавров по направлению государственное и муниципальное управление.
ORIENTAL MOTIFS THAT INFLUENCED WESTERN LITERATURE
Authors:   PhD Student at Bukhara State University, Uzbekistan, Rakhimovna Umurova Nigina
Published: October 2024

This article discusses the influence of Eastern ideas and teachings on Western literature representatives and their works. It examines views on how didactic Oriental motifs inspired European creators' thinking and how the synthesis of Western and Eastern literature is reflected in their works. Information is provided on universal ideas, the essence of Eastern teachings, and their impact on Western literature.
ANALYSIS OF DETERMINANTS OF DEMAND FOR SPECIALIST POLYCLINIC SERVICES AT THE INDONESIAN RED CROSS HOSPITAL, NORTH ACEH
Authors:   Master of Public Health Study Program Faculty of Medicine, Syiah Kuala University, Indonesia, Fikri Rijalul , Saputra Irwan ,   Master of Public Health Study Program Faculty of Medicine, Syiah Kuala University, Indonesia, Suhanda Rachmad ,   Master of Public Health Study Program Faculty of Medicine, Syiah Kuala University, Indonesia, Usman Said ,   Master of Public Health Study Program Faculty of Medicine, Syiah Kuala University, Indonesia, Maulana Maulana ,   Master of Public Health Study Program Faculty of Medicine, Syiah Kuala University, Indonesia
Published: October 2024

Demand Health is an individual's decision regarding choices in utilizing health services. Demand for health services provided in primary, secondary and tertiary health facilities, as well as including public health, varies. Utilization of health services at the Indonesian Red Cross Hospital in North Aceh, especially at specialist polyclinic services, appears to be still very low. This can be shown from the number of visits each month which fluctuates up and down with a trend line showing the forecasting value in a downward direction. This research aims to analyze the Determinants of Demand for Specialist Polyclinic Services at the Indonesian Red Cross Hospital, North Aceh. This type of research is descriptive analytical with a cross-sectional design with a quantitative approach. Data analysis was carried out through univariate and bivariate stages.There is no significant relationship between gender with P value = 0.701, age with P value = 0.383, education level with P value = 0.105, income with P value = 0.75, health insurance with P value = 0.511, waiting time with P value = 0.260, type of disease with P value = 0.895, severity of disease with P value = 0.385 and quality of service with P value = 0.369 for service demand at the specialist polyclinic of the Indonesian Red Cross Hospital, North Aceh. The conclusion from this research is that there are no variables that can significantly directly influence the demand for specialist polyclinic services at the Indonesian Red Cross Hospital in North Aceh, however, the researcher strongly recommends various efforts and initiatives from all levels, both management and implementing officers, to always improve the services provided. to patients in order to create high demand from patients who have visited and people who have never visited the PMI North Aceh hospital.
CHARACTERIZATION OF BREAST LESIONS BY PROCESSING DIGITAL BREAST IMAGE
Authors:   Security Forces Hospital, Riyadh, Saudi Arabia, Binhssan Abdulmuhssin
Published: October 2024

This Rendering to the World Health Organization, women in both developed and developing nations are most likely to develop breast cancer. This illness causes breast cells to grow and multiply out of control. According to research institutes and international organizations, there are various screening methods available based on age, and breast cancer can be cured if detected in time. The Breast Imaging Reporting and Data System (BIRADS) is a standardized system that is commonly used in these techniques to report results and findings. Results are sorted by BIRADS into six categories, numbered 0 through 6. Furthermore, mammography is the most widely utilized screening technique. This study suggests using mammography data processing to identify breast lesions. Adaptive filters are used for image cropping and contrast enhancement during the pre-processing phase. The pectoral muscle is then segmented using segmentation techniques that consider morphological and area growth factors. The lesion is then divided into sections at the muscle and breast levels using the Discrete Wavelet Transform (DWT), which finds any micro calcifications. Furthermore, to distinguish between dense lesions and other kinds of lesions, an area cultivation approach combined with multiple thresholding techniques is employed. Lastly, the obtained segmentation is used to extract textural and morphological features. When expert-segmented and automatically segmented images were compared, the Sorensen Decade similarity index was 0.73, indicating the effectiveness of the suggested method. Considering that the lesion area on a mammogram can only be roughly delineated by hand or automatically, this is a promising outcome.
Assessing risk of physical child abuse recidivism using the HCR-20V3
Authors: Gray Rosie , Laulik Sarah
Published: October 2024

Physical child abuse has been associated with a myriad of harms, not limited to physical injury. Thus, it is vital that children are protected. Forensic psychologists who are required to assess future risk of physical abuse often use the Historical-Clinical-Risk Management-20 Version 3 (HCR-20V3), a well-established tool for general violence. However, the validity of the HCR-20V3 amongst perpetrators of physical child abuse has not yet been established and, whilst there are likely to be similarities between the two groups, there may also be important differences. We explore the potential strengths and limitations of the HCR-20V3 when used with perpetrators of physical child abuse, with reference to the developing evidence base for this type of offence, including indications of unique risk factors that may merit additional attention.
Evaluating the effectiveness of personalised self-soothe boxes on distress levels in an acute adult inpatient mental health setting
Authors: Jenkins Alexandra , Guttridge Lydia , Kapoor Aparna
Published: October 2024

Acute inpatient mental health populations display high levels of distress, characterised by ACEs (Adverse Childhood Experiences), emotion regulation difficulties, impulsivity and self-harm. Self-soothing, a skill underpinned by Dialectical Behaviour Therapy (DBT) and Cognitive Behavioural Therapy (CBT), is the ability to self-regulate. Self-soothe boxes, containing personalised items to promote self-soothing such as distress management techniques, tangible objects and meaningful items, are effective in reducing distress. To date, research on the use of self-soothe boxes has produced promising results. However, this focuses mostly on CAMHS (Child and Adolescent Mental Health Services) and outpatient populations. The current paper outlines a service evaluation guided by the work of Fenton et al. (2023) that aimed to explore the effectiveness of personalised self-soothe boxes in reducing distress across two acute adult inpatient mental health wards. Seven participants developed a personalised self-soothe box, consisting of distraction techniques, sensory items, seeking positives, relaxation and mindfulness activities and coping skills handouts. Participants were encouraged to use this during instances of distress and complete a corresponding questionnaire to reflect on their experiences. Quantitative data was analysed using descriptive statistics. Results revealed that all participants reported a reduction in distress after use and rated sensory items most favourably as a current and future self-soothing strategy. Qualitative data was analysed using Thematic Analysis, with the themes indicating that self-soothing promotes cognitive restructuring and induces a positive change in emotional state. The results of this service evaluation produce evidence and guidance for using personalised self-soothe boxes as a proactive strategy to reduce distress in acute adult inpatient mental health settings, to promote Positive Behavioural Support and reduce restrictive practices.
Propuesta Y Análisis De Implementación De Sanciones Penales, Para Los Responsables De Bloqueos De Carreteras En Bolivia
Authors: Fernández Ovando Mauricio Víctor , Chocata Gomez Jhonsamiel , Apaza Marce Paola Estela , Siles Garcia Oscar Carlos
Published: October 2024

El presente artículo de investigación tiene como objetivo principal describir y analizar una propuesta de ley que modifique el Código Penal de Bolivia para sancionar a los responsables de bloquear carreteras. Para ello, se empleó realizó una revisión exhaustiva de diversos bloqueos que han tenido lugar en Bolivia. Además, se realizó una encuesta digital pública para recoger la opinión de la población sobre esta problemática. El análisis se desarrolló a partir del método deductivo, partiendo de principios generales sobre la normativa penal y los derechos colectivos, para luego examinar casos concretos de bloqueos y sus implicaciones jurídicas y sociales. De esta manera, se busca ofrecer una comprensión integral del fenómeno y la necesidad de una regulación más estricta en esta materia. En las encuestas nos percatamos que un 82.5 por ciento está de acuerdo con la creación de con un Proyecto de ley que sancione a los responsables de los bloqueos de carreteras. La misma que puede modificar los Artículos 213 y 214 del Código Penal.
Inteligencia Artificial en la Educación: Simplificación de los Procesos de Aprendizaje
Authors: Bustamante Mora Freddy Fernando
Published: October 2024

Esta investigación se basó en analizar el potencial transformador de la inteligencia artificial (IA) en el ámbito educativo, por ello, esta se centró en explorar las formas en que la IA puede ser utilizada para mejorar la personalización del aprendizaje, apoyando a los docentes en la identificación y abordaje de las necesidades individuales de los estudiantes. Por esto, según el enfoque de la investigación, esta fue cuantitativa, de tipo exploratoria y descriptiva. De tal modo que su diseño fue no experimental (transversal). La investigación se desarrolló con base a la aplicación de encuestas a 20 docentes y 50 estudiantes de secundaria y bachillerato. Los resultados mostraron que tanto estudiantes como docentes perciben un impacto positivo significativo de la IA en la educación. Así también que las herramientas de IA no solo permiten adaptar el aprendizaje a las necesidades, sino que facilitan la identificación de áreas de dificultad y mejoran la retroalimentación; así como también la comunicación entre docentes y estudiantes. Concluyendo que, es importante destacar el potencial de la IA para revolucionar el aprendizaje, al tiempo que se subraya la importancia de abordar los desafíos éticos y de implementación para maximizar sus beneficios.
Implementation of the Ministry of Agriculture's Communication and Relationship Management Strategy on the Importance of Satu Data Indonesia
Authors: Prasetyo Nurhadi , Prihantoro Edy
Published: October 2024

Satu Data Indonesia (SDI) is a government data governance policy that aims to support the availability of data that is accurate, up-to-date, integrated, accountable and easily accessible and shared between government agencies to support development planning, monitoring and evaluation towards an advanced Indonesia. This policy is contained in Presidential Regulation no. 39 of 2019 concerning One Data Indonesia and is expected to improve data governance. The purpose of this research is to analyze the implementation of effective public communication and relationship management strategies in increasing the Ministry of Agriculture's awareness of the importance of One Data Indonesia Towards Advanced Indonesia. The method used in this research is qualitative with a case study approach. Researchers will conduct in-depth interviews with Ministry of Agriculture officials. The Ministry of Agriculture has shown a strong commitment to the implementation of SDI through initiatives and regulations that have been issued. The Ministry of Agriculture has launched the Agricultural Data Portal as an efficient and comprehensive form of public communication in raising awareness of the importance of One Data Indonesia Towards a Developed Indonesia.
Virtual Communication in the Online Game Counter-Strike as an English Learning Media
Authors: Darmawan Aditya , Haryadi Mujianto  , Resty Mustika Pratiwi
Published: October 2024

This research is motivated by the rise of people who play online games, one of which is the online game Counter-Strike 2, which is favored by the world community. Playing Counter-Strike 2 online games can be used as a medium of learning English because, in Counter-Strike 2 online games, you can communicate with the international community using English. People can improve their English language skills through the experience they get when communicating virtually with the global community by playing Counter-Strike 2 online games. The purpose of this study is for people to take advantage of Counter-Strike 2 online games, not just entertainment media so that they can use them to communicate virtually with the international public as a medium of learning and honing skills in English. This study uses a descriptive method with a qualitative approach. Data collection techniques used by researchers are interviews, observations, and literature studies. The results of this study show that playing the online game Counter-Strike 2 can be used as a medium of learning English. This is due to the player's habit of communicating with each player using the international language, namely English, when the game starts. Learning English through Counter-Strike 2 online games can add new knowledge that does not exist in formal education or books. Namely, we can learn new terms in English, known as slang. If you are used to communicating with the international public, it can increase your confidence in using English.
Initial Understanding of Per and Poly-Fluoroalkyl Compounds (PFAS): Synopsis
Authors: Mainali* Kalidas
Published: October 2024

The increasing attention in academic and industry research on per and Poly-Fluoroalkyl compounds (PFAS) in the environment is a result of growing concern. If PFAS are exposed to human health, they are also known to be dangerous. Utilizing leftover lignocellulosic biomass, biochar is a pyrolytic material that can be used as an inexpensive adsorbent to remove environmental pollutants. It is essential to adjust the physical and chemical properties of biochar due to its low concentration and distinct chemical composition. Most notably, char's high surface area and C and N content are the primary controlling elements during PFAS adsorption. This summary provides background information on PFAS pollutants and possible remediation strategies.
Hypothyroidism Revisited: Defining the Subgroups on Optimal Thyroxine Replacement Who Have Persisting Symptoms
Authors: TA* Welborn
Published: October 2024

Hypothyroid patients on optimal replacement but with persisting symptoms continue to be a challenge for their treating physicians. This commentary is based on a substantial clinical experience with this subpopulation. With the focus on laboratory tests to achieve a diagnosis, aspects of the traditional clinical examination have been overlooked. In particular the routine testing of tendon reflexes has lapsed. A delay in the relaxation phase of tendon reflexes (hypothyroid hyporeflexia), once known as a positive Woltman’s sign, has long been the hallmark sign of overt hypothyroidism. The majority will do well when treated with appropriate thyroxine replacement. This sign is also positive in those patients on thyroxine (T4) with normal T4 and Thyrotropin (TSH) levels if they have symptomatic intracellular Triiodothyronine (T3) deficiency. These patients will respond promptly to combination therapy (T4+T3). This subgroup accounts for more than half of the thyroxine-dissatisfied population. They should be described as having T3-hypothyroidism. The remaining symptomatic patients with normal reflexes have unrelated conditions. A small clearly defined subgroup with autoimmune symptoms and very high anti-Thyroperoxidase (anti-TPO) antibodies (>10 times the upper limit of normal) will respond to total thyroidectomy with a marked improvement that is maintained for 3-5 years. They can be categorised as having TPO-toxic hypothyroidism. Many patients can have persistent symptoms because of psycho-social issues and the burden of having a chronic disease. They have in-denial-hypothyroidism. There are very rare cases of thyroxine allergy. This nomenclature should assist physicians in their diagnosis and management of the several subgroups of patients on thyroxine with persistent symptoms.
Metabolic Engineering of the purine metabolic pathway in brewers yeast to reduce the Purine components in a Beer System
Authors: Liu Jun , Lu* Jian
Published: October 2024

Beer is one of the most popular beverages in the world. However, beer contains excessive amounts of purines, which can increase the risk of hyperuricaemia and gout. During beer fermentation, a key reason is that the purines are not completely absorbed by yeast, which is due to the insufficient ability of purine salvage pathway in beer yeast. In order to improve the absorption capacity of yeast for purines, this study overexpressed four key genes in the purine metabolism pathway (HPT1, APT1, FCY2, and PRM15) in the commercial beer yeast strain SC4, and obtained three yeast engineering strains, namely M1 (SC4 HPT1:: APT1), M2 (M1:: FCY2), and M3 (M2:: PRM15). The expression of purine metabolism-related genes was examined at the transcriptional level, and the expression levels of HPT1, APT1, FCY2 and PRM15 genes were increased by 3.50-fold, 2.37-fold, 2.07-fold and 4.37-fold, respectively, and the overexpression of FCY2 and PRM15 increased the expression levels of HPT1 and APT1 by 3.50-fold and 2.37-fold, respectively. The expression of FCY2 and PRM15 made HPT1 and APT1 more active, indicating that the ability to absorb purines was further enhanced. Applying engineering yeast M3 to 12-degree wort fermentation, the results shown that the free purine base content is reduced by 53.35%, which provides a theoretical basis for reducing the purine content in beer.
Beware with the Quality of Thermodynamic Data Diagnostic Check of Phase Transitions Energetics of Active Pharmaceutical Ingredients
Authors: Verevkin* Sergey P , Zherikova Kseniya V , Vostrikov Sergey V , Kaygorodova Irina I
Published: October 2024

Thermodynamics is crucial for optimizing drug synthesis, developing pharmaceutical formulations and ensuring their stability, effectiveness and safety. The thermochemical properties of active pharmaceutical ingredients with the common biphenyl motif (RS-Flurbiprofen, Diflunisal, Fenbufen and Biprofen) available in the literature were collected, combined with our own complementary experimental results and evaluated. The vapour pressures temperature dependence of RS-Flurbiprofen was measured using the Knudsen effusion method, and the enthalpy of sublimation was obtained from this measurement. The enthalpy of fusion of RS-Flurbiprofen was measured using DSC. A reliable diagnostic method has been outlined to evaluate the quality of the available experimental thermodynamic data of drugs. The data previously available in the literature for RS-flurbiprofen, diflunisal and fenbufen were analysed and diagnosed as "thick". For RS-flurbiprofen, diflunisal, fenbufen and biprofen, the consistent sets of thermodynamic data were evaluated and recommended for the calculations of the pharmaceutic processes. The "paper-and-pencil" concept presented in this paper can be extended to the diagnosis of "sick" or "healthy" experimental thermodynamic data for pharmaceuticals with a structure other than profens.
Populations of Triple Negative and Hormone Receptor Positive HER2 Negative Breast Tumors Share Immune Gene Profiles
Authors: Schmitz Frank , Copeland Wilbert B , Aringa Justine Dell , Newhall Kathryn , Disis Mary L , Stanton* Sasha E
Published: October 2024

Background: Immune therapy has revolutionized the treatment of certain cancers including melanoma and lung cancer. Breast cancer has fewer tumors with high immune infiltrate and Immune Checkpoint Inhibitor (ICI) therapy has shown the most significant responses in the Triple Negative (TN) subtype although roles are emerging in the other subtypes. The presence of Tumor Infiltrating Lymphocytes (TIL) is predictive of response to ICI therapy in metastatic TN and associated with better survival in local TN disease. Hormone Receptor (HR) positive HER2 negative (HR+HER2-) breast tumors do not show improved prognosis with increasing TIL and only a small portion of HR+HER2- tumors respond to ICI in both metastatic and local disease. We therefore sought to identify genetic differences between TN and HR+HER2- tumors to identify how these may contribute to their differences in immune infiltrate. Methods: We contrasted immune-associated gene expression between 119 TN and 475 HR+HER2- breast tumors from The Cancer Genome Atlas (TCGA) and confirmed our findings from 299 TN and 1369 HR+HER2- breast tumors in METABRIC. Results: We found that TN and HR+HER2- tumors can be grouped into immune-high or -low tumors, with both subtypes represented in the immune-high group (40% HR+HER2- tumors of both Luminal A and Luminal B type and 71% TN tumors) in the TCGA. The genes upregulated in the immune-high cluster included GZMB, CXCL9, and IDO1 (Log2FC > 2; Adj. p < 10X10-40). The largest expression difference between the immune-high TN and HR+HER2- tumors was that TN tumors had more abundant Th1 and Th2 CD4+ T cells while HR+HER2- tumors had more abundant fibroblasts (Log2FC > 0.3; Adj p < 10X10-10). Conclusions: Our data suggest that an immune-high signature is not dictated by breast cancer subtype. However, fibroblasts, particularly fibroblast subsets associated with worse outcome, are more abundant in the immune-high HR+HER2- tumors.
Green Synthesis of Silver Nanoparticles Using Origanum onites Extract: Effect of Temperature and Time on Antioxidant and Antimicrobial Activity
Authors: Dogan Sema Yiyit , Kaya Secil , Solak* Ebru Kondolot
Published: October 2024

Origanum species are known to be powerful antioxidants due to the secondary metabolites they contain. It is therefore hypothesized that nanoparticles synthesized by origanum species may have applications in medicine, cosmetics, and food production. This study aimed to investigate the antioxidant and antimicrobial activities of silver nanoparticles obtained at different times (60, 120, and 180 min) and temperatures (30, 60 and 90°C) using O. onites extract. The initial synthesis of Ag Nanoparticles (AgNps) was characterized by UV- spectrophotometry and the surface plasmon resonance band was observed at 430-450 nm under all conditions. The highest absorbance was observed at a wavelength of 425 nm for 180 min at 90°C. The FTIR spectrum showed a peak in the 3.000-3.500 cm-1 range compared to the control, confirming the reduction of silver nitrate. When the particle distribution of AgNPs prepared at three different reaction times was examined by SEM, it was observed that AgNPs with very similar particle sizes were formed. The average particle size was determined to be 171 nm, 169 nm, and 152 nm, respectively, for reaction times of 60, 120, and 180 minutes at 90°C, based on the results of the EDX analysis. The highest DPPH scavenging activity was observed in nanoparticles obtained at the third hour of the 60°C and 90°C reactions. AgNPs obtained at all 3 temperatures showed antimicrobial activity on S. aureus, E. coli, and C. albicans, however, the highest activity was found in AgNPs synthesized at 60°C and 90°C at the 3rd hour. Nanoparticles synthesized from natural materials should not display toxic properties. The AgNPs produced in this study did not exhibit toxicity towards healthy human fibroblasts. The results demonstrated that the AgNPs synthesized within the scope of this study have potential applications in biomedical fields. It was determined that the AgNPs with the highest activity were synthesized at temperatures of 60°C and 90°C at the 3rd hour.
ИССЛЕДОВАНИЕ ПОКАЗАТЕЛЕЙ ОСТРОЙ, КУМУЛЯТИВНОЙ И ХРОНИЧЕСКОЙ ТОКСИЧНОСТИ ПОЛИКОМПОНЕНТНОГО ФИТОПРЕПАРАТА
Authors: Заманбеков Нуртлеу , Азизов Худайберген , Przemyslaw Sobiech , Корабаев Ерганат , Кобдикова Нурзила , Туржигитова Ширин , Баймурзаева Маржан
Published: October 2024

В статье подробно изучены показатели острой, кумулятивной и хронической токсичности комплексного фитопрепарата и его отдельных компонентов, изготовленных из сбора лекарственных растений, обладающих лечебными свойствами. Данные, полученные в результате проведения исследования, показали, что комплексный фитопрепарат и его отдельные компоненты при внутримышечном введении и оральном применении не вызывает гибели лабораторных животных. После введения растительных экстрактов у животных реакции протекали мгновенно и проявлялись в виде кратковременного беспокойства. Клинические признаки слабой интоксикации длятся 5-7 минут, а затем полностью прекращаются. Для изучения возможных последствий метатоксического действия компонентов фитопрепарата при патологоанатомическом вскрытий не выявлено явных патологических отклонений во внутренних органах. Патологическая картина в сравниваемых группах была однотипной и особых признаков не выявлено. В результате анализа данных выявлено,что многократное введение фитопрепарата в высоких дозах приводит к снижению массы тела мышей в испытательных группах. Особенно этот показатель наблюдался при введении фитопрепарата в дозе 1,0 мл ежедневно в течение 30 суток, абсолютное уменьшение массы тела мышей в испытуемой группе составило 10,7% от фоновых значений, а по сравнению с показателями контрольной и интактной групп наблюдалось его достоверное снижение, в среднем до 8,9%. Исследованиями установлено, что поликомпонентный фитопрепарат в оптимальных дозах оказывает стимулирующее воздействие на морфологические и биохимические показатели крови лабораторных животных, а в высоких, наоборот, ингибирующее действие.
ГИСТОЛОГИЧЕСКОЕ ИССЛЕДОВАНИЕ СЛИЗИСТОЙ ЖЕЛУДКА ПРИ ХЕЛИКОБАКТЕРИОЗЕ ЛОШАДЕЙ
Authors: Алимгазина Сабира , Мауланов Амангельды , Джуланов Мардан , Алимбекова Меруерт , Койбагаров Канат , Мырзалиев Ахан
Published: October 2024

В статье приведены данные по гистологическому исследованию желудка лошадей при хеликобактериозе. Отмечается, что данные исследования проводились в условиях юго и юго-восточной регионов Казахстана: КХ «Сункар» Жамбыльского района, Алматинской области, СПК «Азамат 2» Бескарагайского района Абайской области, КФ «Ақылбай» Ескельдинского района Жетысуской области. В указанных регионах у лошадей часто регистрировались колики и признаками заболеваний ЖКТ. Указанные симптома комплексы требовали более тщательного исследования ЖКТ и особенно желудка лошадей. С этой целью проводились ЭГДС исследования (эзофагогастродуоденоскопия) с помощью портативного эндоскопа на 63 лошадям. В процессе исследования были взяты биоптаты из разных мест с язвенными и эрозивными поражениями желудка в размере 1,5 см3. Биоптаты после специальной обработки подвергались окрашиванию иммуногистохимическими методами гематоксилин-эозином и по Лефлеру.
При гистологическом исследовании биоптатов выявлены признаки хеликобактериоза у 17 лошадей, при этом у исследованных животных наблюдались выраженные эрозивные участки, а у 14голов незначительные гиперемии.
Авторы считают, что выраженность воспалительной реакции могут быть независимым фактором, стимулирующим пролиферацию клеток. Пролиферативная активность клеток воспалительного инфильтрата оказалась наибольшей в антральном отделе. В биоптатах из тела желудка отмечалась минимальная экспрессия клетками воспаления.
EFFECT OF DIFFERENT FEEDING LEVELS AND RATION STRUCTURE ON INCREASING SHEEP PRODUCTIVITY
Authors: Кулатаев Бейбит , Искаков Кайрат , Сагдат Елболсын , Айтжанов Рустембай
Published: October 2024

The article considers the process of identifying different amounts of cleavable and non-cleavable basic food in the scars of protein fractions of protein in the south-east of Kazakhstan. The main factors influencing feed intake during fattening are the physical form of the feed, the energy concentration in the dry matter of the diet and the live weight of the sheep.
When feeding granulated feed mixtures, feed losses in the form of scraps are reduced by 20-25%, dry matter consumption increases by 10-15% and amounts to 45-50 g per 1 kg of live weight, which allows increasing the total consumption of nutrients by 25-30%, obtaining more meat production by 26.20%, lamb wool by 15.65%, reducing feed costs per 1 kg of gain by 2 feed units or 30%.
The proteins most intensively broken down in the rumen of sheep are those of clover and alfalfa grass (83.5-84.6%), grass from foothill and mountain pastures (70.0-71.7%), alfalfa hay and haylage (76.6-81.3%), corn silage (78.6%), and oat and barley grain (84.0-85.3%).
Intensive fattening of fat-tailed meat-and-fat sheep using our detailed feeding standards, feed mixtures, and compound feeds ensures an average daily gain of 200-230 g, a carcass weight at slaughter of 23-26 kg, a meat-pulp yield of 76-78% with an expenditure of 6.0-7.0 feed units, 78-80 MJ of exchange energy per 1 kg of live weight gain.
Evaluation of Integrated Social Welfare Data Management in Penajam Paser Utara District
Authors: Febrianto Amirul , Djabar Sadly Abdul , Wahyu Wahyu
Published: October 2024

This study seeks to examine the influence of the efficacy of Social Welfare Integrated Data Management in Penajam Paser Utara Regency. The study was carried out at the Social Services and Villages Department in Penajam Paser Utara Regency. Data collection is conducted via observation, interviews, and documentation. This study employs a descriptive methodology utilizing a qualitative approach with inductive data analysis. Data analysis approaches employ data reduction, data display, and conclusion formulation or validation. The findings of this study indicated that the effectiveness of updating DTKS yields results due to monthly changes, including the addition of impoverished families and the removal of families deemed capable. Regarding the efficiency of DTKS management, it is acknowledged as more efficient in operations, data storage, and other technical aspects for both Data Managers at Dinas Sosial and Operators at Village Governments, in terms of adequacy. The quantity of social assistance recipients is substantial, yet the trend indicates a decline in recipients over time, reflecting a reduction in impoverished families in Penajam Paser Utara Regency. Regarding equity, it is evident that the Ministry of Social Affairs' social assistance program encompasses all 54 villages in the regency. In terms of responsiveness, The Dinas Sosial of Penajam Paser Utara Regency demonstrates considerable responsiveness in executing its activity budget program; however, at the Village Government level, the responsiveness regarding the management of DTKS is markedly deficient. While some villages are active, a significantly greater number have failed to update the DTKS.
The Influence of Motivation and Leadership Style on Employee Performance of Regional Financial and Asset Agencies
Authors: Aris Lukas , Mujahid Mujahid , Bidol Syamsuddin
Published: October 2024

The study aims to identify and analyze the influence of motivation and leadership style on the performance of officials at the Office of the Regional Financial and Asset Authority of Paniai District of Central Papua Province. The research was conducted in the office of the Paniai district financial and asset agency located on the Kaisepo street in the Eastern Pania district. The sample in this study is a total of 45 civil servants. Research findings show that motivation influences staff performance, leadership style influences employee performance and simultaneously motivation and leadership styles influence staff performance at the financial and asset offices of the district of Panya Province of central Papua.
The Effect of Competency Development and Work Creativity on Employee Performance
Authors: Arifin Adnan , Mujahid Mujahid , Suyuthi Nurmadhani Fitri
Published: October 2024

This study aims to analyze the effect of competency development and work creativity on employee performance at PT Pelindo Makassar. Employee competency and work creativity are seen as two important factors that complement each other in increasing employee productivity and innovation in a dynamic work environment. Competency development ensures that employees have the knowledge and skills needed to carry out tasks efficiently, while creativity allows employees to find innovative solutions to solve problems. This research method uses a quantitative approach with a correlational design to measure the relationship between these variables. Data were collected through structured questionnaires distributed  to 164 employees of PT Pelindo Makassar. The sampling technique used was stratified sampling. Data were analyzed using multiple linear regression with the help of SPSS version 25 software. Validity, reliability, normality, multicollinearity, and regression tests were carried out to ensure the quality of the analysis.The results showed that both competency development and work creativity have a significant positive effect on employee performance. Competency development contributes to increased productivity, service quality, and adaptation to change, while work creativity drives innovation, operational efficiency, and job satisfaction. Simultaneously, both variables contribute 58.9% to increased employee performance. These results emphasize the importance of competency and creativity development strategies in improving company performance and competitiveness.
Theoretical Comparison of Wavelet Transform and Fourier Transform in SARIMA-GANN Forecasting Model
Authors: Sudin Suhizaz , Kar Yan Choong , A. Raof Rafikha Aliana , Rhui Jaan Ong
Published: October 2024

Seasonal Autoregressive Integrated Moving Average (SARIMA) model which combine seasonal differencing with an ARIMA model are used when the time series data exhibits periodic characteristics. It is popular in modelling and forecasting demand as its ability in identifying the patterns and seasonality of the series and grasping the linear trend of the series effectively. However, the assumption of linearity in many time series events may not be satisfied in practice and thus the accuracy needs to be improved. Besides, it is unable to extract the non-linearity of the series. Genetic Algorithm based Neural Network (GANN) is proposed to combine with SARIMA to overcome its shortcomings but it might occur the overfitting event. Therefore, it is important to reduce the complexity of the input data of the neural network overhead to overcome this problem. This paper contains the section of explanation of both Wavelet Transform (WT) and Fourier Transform (FT) and the discussion of the comparative pros and cons among each other in analysing signals especially in handling the overfitting problem by neural network.
Identifying Students’ Preference in Learning Through ODL (Open Distance Learning) for Multimedia Course
Authors: Wan Mohammad Wan Anisha , Abdul Wahab Naemah , Mohd Mydin Azlina , Omar Mahanim , Abd Samat Ahmad Asri , Gumilar Langlang
Published: October 2024

A Teaching and learning computer course for non-computer background novice learners using online mode in the midst of COVID-19 pandemic is very challenging. For students in higher education, computer courses like Interactive Multimedia are a crucial addition to their skill set, regardless of subject area. Students who complete this course will receive both practical resources on multimedia applications and theoretical concepts. This enables students to enhance their knowledge on such applications and apply it in their studies. This makes it possible for students to learn more about these applications and use it in their academic work. This study was carried out in order to determine the technical problems and challenges, the best methods for lectures, exercises, and reference materials, as well as the ideal platform for lectures delivered via Open Distance Learning (ODL). This study was conducted by the Department of Computer and Mathematical Sciences, Universiti Teknologi MARA Cawangan Pulau Pinang. An online survey via google form was created to collect data from 109 third semester Diploma in Tourism students from the Faculty of Hotel and Tourism Management. The findings will be used to enhance the online lectures teaching technique for CSC253 course in the upcoming semesters, increase students’ understanding and interest in this subject along with improving students’ grade. Results show that most of the students prefer live hands-on class by the lecturer as they can see clearly all the features and functions shown by the lecturer during the live class.
Symptom-Based Medicine Recommendations Used in Natural Language Processing
Authors: Hassan Md. Maruf , Chowdhury Hridoy , Arman Md. Shohel , Jahan Hasnur , Rahman Shadikur , Yaakob Naimah , Ahmad R. Badlishah , Ong Bi Lynn , Kahar Nur Farhan
Published: October 2024

Humanity and viral diseases have long been at odds. However, the idea of evolution contends that each livelihood thing in the earth, along with which is tiny, continuously battles for its life. As a result, the spread of viral infection among people has a significant impact on illness and mortality. Viruses are always changing quickly. Even though we have now several methods of edge cutting for the discovery, inhibit, and also therapy contagious illnesses, the initiation of latest illness still poses a serious danger to the condition of health of the whole world community. One such instance is the newly discovered virus. COVID-19. New virus is adding in the world and new medicine also adding in the pharmaceutical department. So, there is coming new medicine to doctors and they are suggesting them to the patients in prescription. Medical staff workers, on the other hand, are noted for their shoddy cursive script. Approximately 7,000 casualty each annual tine in the United States is assigned to incapability for reading physician’s scripted prescriptions written by their hand. The matter might to be poor as more Bangladesh physicians and other minimum advanced countries handwrite their medicines on paper. As a result, patients and pharmacists frequently provide the wrong drugs to patients. For creating it easier for understanding medicines scripted by physicians, the study builds an offline identification of prescription which is handwritten. The Medex webpage and medical agents in Bangladesh's Noakhali district provided samples of prescription and drug information for this inquiry.
GSM Based of Unclad Fibre Temperature Sensor for Electrical Transmission Cable Monitoring System
Authors: Ngajikin Nor Hafizah , Abdul Kadar Muhammad Sazlan , Yaacob Maslina , Md Yasin Muhammad Zakir , Che Abd Rashid Nurfatihah , Ahmad Hafisoh , Yulianti Ian
Published: October 2024

This paper presents a temperature monitoring system for an electrical transmission cable utilizing a global mobile service (GSM)-based unclad fibre sensor. The developed system consists of GSM module, Arduino controller, unclad plastic optical fibre (POF) sensor, light emitting diode (LED) and photodetector. The unclad POF sensor was chosen due to its immunity towards electromagnetic interference as well as its high sensitivity performance. In this work, the transmission cable hazardous temperature is set at 70oC, which is the maximum operating temperature value provided by the National Electrical Code (NEC) NFPA 70. For system characterization, temperature of the cable was varied from 30oC to 70oC. Photodetector output voltage for this temperature variation were recorded at 660 nm and 770 nm operating wavelength. The recorded data shows that the sensor sensitivity performances at 660 nm wavelength are found superior than 770 nm wavelength, which are 0.9710mV/oC and 0.9699mV/oC respectively. As for the GSM communication system, the system was characterized based on accuracy of the information send via GSM text message and its delay. The developed system offers economical and practical monitoring system to be adopted for transmission cable temperature monitoring in remote area.
Action Transformer: Model Improvement and Effective Investigation with MPOSE2021 and MSR Action 3D Datasets
Authors: Hoang Van-Dung , Phu Khac-Anh , Lan Le Van-Tuong
Published: October 2024

The AcT (Action Transformer) model has shown promising results in action recognition tasks. However, achieving high accuracy in complex and dynamic action sequences remains a challenge. In this paper, we present an approach to improve the accuracy of the AcT model by increasing the model's training complexity, validated on the MPOSE2021 and MSR Action datasets. Our method enhances the AcT model by incorporating a multi-level feature fusion technique. We introduce additional convolutional and pooling layers to capture more detailed spatial and temporal information from the input data. This increases the model's ability to discriminate between subtle action variations and improves its accuracy in recognizing complex actions. We evaluate the effectiveness of our proposed approach through extensive experiments on the MPOSE2021 and MSR Action datasets. The results demonstrate that our enhanced AcT model achieves significantly improved accuracy compared to the baseline AcT model and outperforms existing state-of-the-art methods. Our method effectively captures the intricacies of complex actions and provides more accurate predictions.