bluuebunny/crossref_metadata_2025 huggingface dataset:
Pedagogía e historia. La educación como tiempo de la historia
Authors: Heredia Duarte María Isabel
Published: February 2020

Desde una perspectiva histórico-filosófica, este artículo de reflexión propone una relación cercana entre pedagogía e historia. Como producto de las investigaciones de la autora en el marco de su tesis de doctorado, el trabajo realiza un recorrido por la historia del futuro, correlacionándolo con la educación, para demostrar que, si bien lo que llamamos tiempo es la relación entre el pasado y el futuro, es la educación como posibilidad de perfeccionamiento humano lo que la hace posible. En este sentido, la educación es el futuro mismo. Por tanto, la educación sería organizadora del tiempo histórico y no un correlato menor en el desarrollo de la modernidad. Esta postura permite interrogar algunas verdades que hasta el momento han sido incuestionables. Una de ellas es la relación intrínseca entre pedagogía y sociología, que ha fortalecido la creencia de que la educación es, por excelencia, un hecho social. Este piso sociológico habría encerrado la educación en una práctica,lo que ha provocado, en parte, su recorte como proyecto humano, más allá de la sociedad. Finalmente, se vislumbra una crisis de la historia como crisis de la educación, basada en el encierro enel presente y en la imposibilidad de formular fines genuinamente generales
Prácticas formativas de la familia: la configuración de la mujer formadora
Authors: Saénz Obregón Javier , Salcedo Ruiz Manuela
Published: February 2020

Este artículo es resultado de una investigación en curso. Presenta uno de los resultados del caso de la formación de la familia, del proyecto de investigación “Prácticas formativas por fuera de la escuela”. Expone el abordaje del proyecto a partir de su uso de los conceptos de formación (Bildung), gobierno, contraconductas y prácticas de sí, así como de suspreguntas en torno a la dimensión conceptual, las características y los efectos de las prácticas formativas. A partir de un examen detallado de textos de formación de la familia (tratados, manuales y una novela ejemplarizante) entre el siglo xv y el xx en Europa Central y Colombia, se describen y analizan tres acontecimientos en la configuración de la mujer como formadora: i) la valoración católica de su naturaleza como moral e intelectualmente débil; ii) su configuración como principal responsable de la formación moral de sus hijos; iii) su valoración como moralmente superior al hombre y, por tanto, como responsable de la formación moral de su esposo. El texto problematiza y esboza algunas ideaspara comprender dos asuntos paradójicos que emergen del examen de estos acontecimientos: si es concebida como moralmente débil, ¿por qué se le asigna el papel de formadora moral de sus hijos?, y posteriormente, si es valorada como moralmente superior al hombre y como su formadora moral, ¿por qué sigue ocupando un lugar subordinado a él?
As reconfigurações do imperativo da inclusão no contexto de uma governamentalidade neoliberal conservadora
Authors: Lockmann Kamila
Published: February 2020

Esta reflexão de investigação sustenta o argumento de que vivemos, no contexto brasileiro atual, uma reconfiguração da inclusão como imperativo de Estado. A partir da instauração de uma governamentalidade neoliberal conservadora, a inclusão parece não se constituir mais como a rega máxima do neoliberalismo e a exclusão reaparece como uma das estratégias de governamento da população. O texto apresenta uma breve análise documental sobre o PL 3261/2015, projeto de lei em tramite no Brasil, que autoriza o ensino domiciliar na educação básica. Os argumentos apresentados sustentam que a exclusão é transformada num direito —o direito das famílias de optarem ou não pela educação domiciliar. Diante desse quadro, o princípio político do comum é pensado como uma estratégia de resistência ao neoliberalismo, possibilitando formas outras de ser e viver no mundo.
"What do we do with our lives?" Conversations About Work and Conversations at Work
Authors: Labrecque Lisandre
Published: February 2020

Everyday conversations reveal the great normative preoccupations of societies, both in their themes and in their modalities. The world of work is one of the main worlds of conversation we have studied: we talk about work and we talk at work. Contemporary individuals seek to singularize themselves through work and in conversations about work: it becomes a statutory and an aesthetic experience insofar as it resonates with a way of life and a broader experience of reality.
Political correctness and linguistic creativity in the job market. How much do they (mis) inform?
Authors: Delekta Ilona
Published: February 2020

The article examines how political correctness (PC) affects work-related lexis. A particular focus is put on English bizspeak that aims to fulfil PC demands by using creative vocabulary and euphemisms to motivate employees, stimulate their creativity, and win or keep customers. A brief theoretical outline is followed by an analysis based on authentic material. The results show that such colourful language may contradict PC postulates and impede effective communication.
Languages at work in the Basque Autonomous Community
Authors: Van der Worp Karin
Published: February 2020

En la Comunidad Autónoma Vasca, la presencia de la lengua minoritaria local, el euskara, ha aumentado paulatinamente en el lugar de trabajo gracias a políticas lingüísticas recientes, aunque la lengua mayoritaria local, el castellano, sigue siendo claramente predominante. Al mismo tiempo, a consecuencia de la internacionalización, el inglés también ha ganado en importancia como Lengua Franca en las actividades profesionales internacionales. Este estudio analiza las percepciones de los profesionales y futuros profesionales acerca de este repertorio lingüístico “glocal” en el lugar de trabajo de la Comunidad Autónoma Vasca.
Integrating corpus-based tools in translators’ work environment: cognitive and professional implications
Authors: Peraldi Sandrine
Published: February 2020

Despite the growing recognition of corpora-induced benefits for translation quality, the use of corpus technology remains an exception in a professional setting. This article describes the results of a pilot study aimed at integrating corpus-based tools into the work environment of legal/financial translators. In particular, the paper examines resistance and success factors with a view to encouraging the progressive integration of corpus technology into translators’ toolboxes.
Bioflux Analyses: Modelling v2
Authors: Weise Tobias , Boettcher Bettina , Vylkova Slavena
Published: February 2020

Biofilm formation under shear flow conditions was monitored using the Bioflux1000 device (Fluxion Biosciences, Inc.). In short, Candida albicans overnight cultures were washed in pre-warmed RPMI medium. Cells were seeded for 2-5 sec from the outlet well into the channels of Bioflux1000 flow chambers, which were primed before with warm medium. The cells were allowed to adhere to the channels for 90 min without any flow, followed by removal of non-adherent cells by flowing fresh, pre-warmed RPMI medium for 5 sec. Shear flow was set for time series experiments over 24 h biofilm formation and images were captured every 20 min. Two channels were investigated in parallel having a 10 × magnification to allow a direct comparison between a mutant and a reference (wild-type) strain. Image capturing and stacks to movies was performed using the MetaMorph® Software (Molecular Devices). An ODE model reflecting the logistic growth as well as the lag phase was fitted to the individual experiments. Fitting was carried out by minimising a cost function (unweighted least-squares-based) using the Nelder-Mead algorithm. Growth rate time series generated from the fitted model were used to compare wild type and mutant regarding the maximum observed growth rates at their respective time points. All computations were performed using the programming language python (version 3.6.9) and the additional packages numpy (version 1.16.2), pandas (version 0.25.0), and scipy (version 1.3.1).
Kulak Akıntı Kültürlerinden İzole Edilen Pseudomonas aeruginosa Suşlarının Antibiyotik Duyarlılıklarının Değerlendirilmesi
Authors: ALKAN ÇEVİKER Sevil , GÜNAL Özgür , MEHEL Dursun Mehmet , ÖZGÜR Abdülkadir , KILIÇ Süleyman Sırrı
Published: February 2020

Amaç:
Orta kulak ve mastoidin kronik enflamasyonu ile karakterize olan kronik
süpüratif otitis media (KSOM) sıklıkla akıntı ve işitme kaybı ile belirti
verir. Süpürasyondan sıklıkla sorumlu olan bakteriyal sınıf Pseudomonas’lardır. Artan direnç oranları nedeniyle
tedavi güçlüğüne ve klinik yanıtsızlığa neden olabilen Pseudomonas’ların
önemi giderek artmaktadır. Bu çalışmada, hastanemiz Kulak Burun Boğaz
Hastalıkları Kliniği’nde KSOM tanısı konulan ve dış kulak yolundan alınan
kültürlerde üreyen Pseudomonas aeruginosa cinsi bakterilerin antibiyotik duyarlılıklarının
araştırılması ve benzer çalışmalarla kıyaslamaların yapılması amaçlandı.

Gereç ve Yöntemler: Ağustos
2015- Ağustos 2018 tarihleri arasında hastanemiz Kulak Burun Boğaz Hastalıkları
Kliniği’nde kulak akıntı kültürlerinden izole edilen Pseudomonas aeruginosa suşlarının antibiyotik duyarlılıklarının
araştırıldı. Üreyen mikroorganizmaların tanısında rutin mikrobiyolojik
yöntemler kullanıldı.

Bulgular: Çalışma
döneminde 34 hastanın kulak kültürlerinde Pseudomonas
aeruginosa üremesi saptandı. Bu hastaların 19 (%55.8)’u erkek, 15 (%44.2)’i
kadın, yaş ortalaması 44.9 (15-69)  idi. Pseudomonas aeruginosa suşlarının
antibiyogramları incelendiğinde; en duyarlı oldukları antibiyotik sınıfının
kolistin (%100), karbapenem grubundan imipenem (%82.3) ve meropenem (%82.3)
olduğu; en fazla direncin ise netilmisin (%52.9), piperasilin (%41.2),
piperasilin/tazobaktama (%41.2) ve levofloksasine (%41.2)  karşı olduğu saptandı. Tedavide en sık
kullanılan antibiyotik olan siprofloksasine karşı ise %61.7 oranında duyarlı
olduğu belirlendi.

Sonuç:
KSOM’da etken patojenin duyarlılık profilleri zaman içerisinde değişiklik
gösterebileceğinden, komplikasyon gelişme riskinin azaltılması, zaman ve
maliyet kaybının en aza indirgemesi amaçları ile antibiyotik duyarlılıkları
takip edilmeli ve antibiyotik tedavileri güncel verilere göre düzenlenmelidir.
REHABILITATION OF THE ESTHETIC ZONE USING MULTIPLE ADJACENT INDIVIDUAL IMPLANT-SUPPORTED RESTORATIONS: WHERE ARE THE LIMITS?
Authors: Bernal Dulcey Guillermo , Murgueitio Rafael , Rios Hector Fabio
Published: February 2020

Rehabilitation of the partially edentulous anterior maxilla is considered one of the most difficult challenges for the restorative dentist due to the esthetic, functional and psychological implications. Implant-supported restorations provide an appealing treatment alternative that responds to today’s patient expectations. The gold standard for this scenario has been the use of an implant-supported fixed partial denture with pontics that masks the soft tissue deficiencies, with acceptable esthetic results. However, nowadays patients are looking for individual single crowns since they believe that this type of restorations resemble the natural dentition, are easy to clean and floss. From the dentist perspective, they are easy to maintain and in case of prosthetic complications they can be repaired or changed without compromising the adjacent restorations. Three parameters have been identified that could guide the decision-making process when multiple adjacent implant supported restorations (MAISR) are selected as the treatment of choice: 1) Smile line 2) Inter-implant distance and tooth-implant distance 3) Patient's expectations and ability to clean.
EPIDEMIOLOGÍA Y COMPLICACIONES DE LAS FRACTURAS FACIALES: UN ESTUDIO RETROSPECTIVO DE 5 AÑOS
Authors: Deboni Maria Cristina Zindel , Lanas Guillermo , Paredes Fernando , Vallejo Kleber , Lanas Andrea
Published: February 2020

Introduction: regional epidemiological studies involving facial trauma are needed to develop more efficient ways of providing health care services. The time elapsed from the occurrence of facial trauma to its definitive treatment can affect clinical outcomes in terms of interventions, resolution, and complications. The aim of this study was to verify if there is a relationship between the different fracture types, their treatments or time intervals for clinical resolution and the onset of complications. Methods: a retrospective study was conducted by means of the clinical records of the Eugenio Espejo Hospital in Quito, verifying the epidemiological data on the clinical evolution of facial trauma patients between 2012 and 2016, and registering data such as age, gender, fracture type, time elapsed until its definitive treatment, and onset of complications. Clinical records lacking these data were excluded. Results: most cases occurred outside Quito (64%). There was no relationship between harmful habits, fracture displacement, type of access or fixation, or presence of comorbidities and the onset of complications. The odds ratio (95% confidence interval) for complications was OR = 0.301(0.170-0.536), so there is a 70% increased chance of developing some complications if treatment is performed one week after trauma occurs. Conclusion: reducing facial fractures before a week can decrease the onset of complications and sequelae.
GUÍA DE PRÁCTICA CLÍNICA PARA LA PREVENCIÓN Y EL TRATAMIENTO DE ENFERMEDADES PERIIMPLANTARES
Authors: Marín Jaramillo Rubiel Antonio , Villegas Giraldo Alejandro , Duque Duque Andrés , Giraldo Aristizabal Astrid , Muñoz Giraldo Viviana
Published: February 2020

Introduction: the incidence of peri-implant diseases is high, and their optimal management is still debated. The purpose was to explore the levels of available evidence and to suggest evidence-based recommendations for the treatment of peri-implant mucositis and peri-implantitis. Methods: a clinical practice guideline was developed using the Scottish Intercollegiate Guidelines Network (SIGN) criteria. A search strategy was formulated, and a critical review of the following evidence was performed: 1) prevention of peri-implant diseases, 2) treatment of peri-implant mucositis, and 3) treatment of peri-implantitis. Systematic reviews and randomized controlled clinical trials were the primary study types identified in the literature. Current levels of evidence were established and recommendations were provided. Results: a total of 67 articles were included. Regarding the prevention of peri-implant diseases, there is strong evidence for the involvement of patients in a regular maintenance program according to their risk profile. Regarding the treatment of peri-implant mucositis, infection control measures are recommended; controversy exists over the usefulness of antimicrobial agents, and there is evidence against the use of antibiotics. Selection of the peri-implantitis treatment method depends on the severity of the condition and patient-related factors. Resective and regenerative therapies may be used for treatment. The use of systemic antibiotics favors the response of clinical parameters. There is conditional evidence for the use of other adjunctive therapies. Conclusions: the best way to prevent peri-implantitis is to prevent peri-implant mucositis through adherence to supportive periodontal therapy. Treatment of peri-implant diseases depends on local and systemic conditions that affect the success of other treatment options.
FACTORES ASOCIADOS A LA FLUOROSIS DENTAL EN NIÑOS Y JÓVENES DE LA CIUDAD DE MONTERÍA, COLOMBIA
Authors: Espitia Cabralez Enalbis Esther , Lozano Flores Milena Cecilia , Montoya Vega Martha Elena
Published: February 2020

Introduction: dental fluorosis is the hypomineralization of enamel produced as a result of fluoride intake for a prolonged period during enamel formation. The aim of the present study was to identify the factors associated with dental fluorosis in children and teenagers from the city of Montería, Colombia. Methods: a quantitative, descriptive and retrospective study was conducted in a sample of 136 dental fluorosis cases in schoolchildren aged 6, 12, 15 and 18 years reported to the Surveillance and Control System from January to December 2016. Results: there was fluoride exposure in 81.6% of schoolchildren covered by the subsidized health system—the mechanism by which the poorest population, with not enough resources to pay, can access health services through a subsidy offered by the state in Colombia—. 89% were from the municipal center, defined by Colombia’s National Administrative Department of Statistics (Departamento Administrativo Nacional de Estadística, DANE) as the geographical area bounded by an urban perimeter, where the administrative headquarters of a municipality are located. 47% of patients had cavities. Tooth brushing in a frequency higher than three times a day was predominant with 48.5%, and the use of toothpaste on more than 3/4 of the brush with 52%. 71.3% of patients said they did not swallow toothpaste, and 93.4% did not swallow mouthwash. 82.4% of patients did not receive topical fluoride in the last year. Conclusions: several factors are more highly associated with dental fluorosis, such as the amount of toothpaste during brushing, the habit of brushing three or more times a day, consumption of diet salt, and unintentional intakeof toothpaste at an early age. Most schoolchildren had a moderate degree of dental fluorosis.
Physicochemical properties of two epoxy resin-based sealants: Topseal® and Adseal™. a comparative study
Authors:   Universidad Nacional de Colombia, Cardona-Hidalgo Julio César , González-Carreño José Manuel ,   Universidad Nacional de Colombia, Avendaño-Rueda Julio César ,   Universidad Nacional de Colombia
Published: February 2020

Introduction: a new epoxy resin-based root-canal sealer (AdSeal™) recently appeared on the market. The aim of this study was to evaluate the radiopacity, flow rate, and film thickness of this sealant compared to Topseal®. Methods: the tests were conducted in compliance with ISO 6876:2012 standards. To evaluate radiopacity, 5 discs of each sealant measuring 10 mm in diameter by 1 mm thick were crafted, comparing their radiographic density in mm of aluminum (Al). For flow rate analysis, 0.05 ml of sealant were placed between 2 glass plates under a weight of 120 g for 10 minutes. The diameters of the formed discs were measured with a calibrator and analyzed with the imageJ software. For film thickness analysis, the sealants were placed between 2 glass plates, applying a load of 150N with a universal testing machine (AGIS 5KN) for 10 minutes. Distance between the glass plates was measured using a stereomicroscope at three equidistant points. Results: Topseal® showed more radiopacity (Wilcoxon p < 0.05) and less flow rate than AdSeal™, with statistically significant differences (Anova p = 0.0001863). The film thickness values are above the limit allowed by standard 6876, possibly because of the methodology used in this study; however, no statistically significant difference was found between the sealants (Anova p = 0.4927). Conclusions: the radiopacity and flow rate of AdSeal™ and Topseal® sealants comply with the ISO 6876:2012 standard, but the film thickness values fail to meet the standard.
PRODUCCIÓN CIENTÍFICA SOBRE CARIES DENTAL ENTRE 2014 Y 2018: ESTUDIO DE INDICADORES BIBLIOMÉTRICOS EN WEB OF SCIENCE
Authors: Jaimes Monroy Gustavo , Valderrama Salgado Ángela Ivonne , Prieto Cárdenas Elver Steven , Rincón Bermúdez Claudia Milena
Published: February 2020

Introducción: el objetivo consistió en realizar un estudio bibliométrico en relación con la producción científica sobre caries dental entre los años 2014 y 2018. Métodos: se realizó un estudio de indicadores bibliométricos, con análisis temporal para cinco años, de 2.291 publicaciones en la base de datos de Web of Science. Se revisaron las variables de producción anual de artículos, revistas, autores, cooperación y análisis de citas. Resultados: se ha producido información de manera sostenida a través de los años de estudio. Paiva, de Brasil, es el autor con el mayor número de publicaciones (n = 33); la revista con mayor cantidad de artículos es Caries Research (n = 176). Estados Unidos y Brasil son los países con más divulgaciones asociadas a este tema. Conclusiones: existe una producción de publicaciones en caries dental que indican la vigencia de la temática y la importancia de los grupos científicos asociados que investigan principalmente en el campo del diagnóstico, la prevención y la salud pública.
Silikon bazlı kimyasal maddelerle emprenye işleminin odunun bazı fiziksel ve mekanik özelliklerine etkisi
Authors: KILIÇ Ceyhun , YILDIZ Ümit
Published: February 2020

Doğu Karadeniz Bölgesinde doğal olarak yetişen ve orman ürünleri sanayinde yoğun olarak kullanılan doğu ladini (Picea orientalis L.) ve doğu kayını (Fagus orientalis L.) odun örnekleri silikon bazlı emprenye maddelerinin %10 ve %50’ lik konsantrasyonlarında dolu hücre yöntemi ile emprenye edilmiş ve emprenye sonrasında odun özelliklerinde meydana gelen değişiklikler bazı fiziksel ve mekanik test yöntemleri ile belirlenmeye çalışılmıştır. Çalışmada kullanılan silikonlar ticari bir firmadan temin edilmiştir. Fiziksel özelliklerden yoğunluk, mekanik özelliklerden liflere paralel basınç direnci ve dinamik eğilme (şok) direnci testi yapılmıştır. Çalışmadaki tüm testler 10 tekrarlı yapılmış olup yoğunluk ve liflere paralel basınç direnci testleri için 2x2x3 cm, şok direnci için 2x2x30 cm boyutlarında örnekler kullanılmıştır. Sonuç olarak emprenye edilen örneklerin yoğunluk ve liflere paralel basınç direnci, kontrol örneklerine yakın bulunmuştur. Ancak emprenye edilen örneklerin şok direncinde azalmalar olduğu gözlenmiştir. Dinamik yüklerin etkisinde kalan köprü, merdiven, gibi yerlerde silikon bazlı emprenye maddeleriyle emprenye edilen ahşabın kullanılmaması önerilmektedir.
Biological value of raspberry fruits
Authors: Voitsekhivskyi V. , Andrusyk A. , Vaskivskyi B. , Voitsekhivska O. , Vaskivska S. , Tokar A.
Published: February 2020

The human body needs a constant flow of biologically active substances. Berry products, including raspberries, are a source of natural and affordable BAS. Raspberry berries contain a complex of BAS, in particular fructose, glucose, organic acids, vitamins A, B1, B2, C, P, E, essential oils, pectins, fiber, complex of polyphenols, copper salt, iron, potassium, folic acid, etc. Berries are salicylic acid and can for a long time maintain the beneficial properties of various processed products. Berries contain a lot of food fibers, it is beneficial for digestion. Berries contain betasitosterol and anthocyanins have anti-sclerotic properties, and coumarins normalize blood coagulation. Berries contain a lot of food fibers, it is beneficial for digestion. Raspberry berries contain coarse dietary fiber, β-sitosterol, anthocyanins and coumarins, these substances have a positive effect on digestion, have anti-sclerotic properties and normalize blood clotting. The purpose of the research aimed at carrying out a comparative characterization of the basic biochemical substances content and the quality of various berries and raspberry hybrids grown at the research field "Fruit and Vegetable Garden" of NULES of Ukraine. During the research the complex of international and state regulatory documents were used, in particular: the berries were selected in the state of technical maturity, in accordance with the state standard 7179: 2010; the sample size corresponded to ISO 874-2002; the determination of the components of the biochemical composition was carried out: the content of dry soluble substances were determined according to ISO 2173-2013, invert sugars – state standard 4954: 2008, titrated acids – state standard 4957: 2008, ascorbic acid – ISO 6557-2: 2014; organoleptic evaluation – according to the generally accepted methodology. Based on the obtained results, it was found that among the studied samples of berry varieties Babine Lito, Sontse Kieva, hybrids – Hybrid №4a, Hybrid №2 were characterized by the highest organoleptic and biochemical parameters, therefore it is expedient to use them both for consumption in a fresh form and for processing.
The obtained results should be taken into account during the planning of raspberry planting and in further selective work during the creation of competitive varieties and hybrids of raspberries with a high content of biologically active substances in berries.
Eeffect of an aquaeous extract of Phaseolus vulgaris pods on morphological properties of post-burn esophagus
Authors: Raetska Ya.
Published: February 2020

The most widespread chemical damage in children – burn of the esophagus. It occurs when accidentally swallowing substances that have in their composition alkali, acid or other caustic substances. The depth of burn depends on the concentration and time of contact of the mucous membrane with the affecting agent. As a result of penetration of alkalis and contact with the wall of the esophagus, along with necrosis, damage to the mucous membrane, submucosal and muscular membrane of the esophagus occurs. Despite a large number of drugs that have been tested in the treatment of complications caused by esophageal burns, there is little information that would indicate the high effectiveness of the previously used drugs. The analysis of literature data shows the positive influence of polyphenols of natural origin on the normalization of physiological and biochemical parameters in various pathologies. The extract of common beans (Phaseolus vulgaris pods extract (PVPE)) is an example of a rich bioactive component of the source with beneficial characteristics for humans. Therefore, the purpose of our work was to investigate the effect of the Phaseolus vulgaris pods extract on the healing of post-burns wounds. When morpho-functional characteristics of the esophagus changes in the conditions of alkaline burn of the esophagus of the 2nd degree, it was shown that at 1 day of the experiment there is a violation of the mucous membrane, which manifests itself in the destruction of the multilayered epithelium, namely, in the submucous membrane there is a significant accumulation of leukocytes, leukocytic infiltration is fixed in the partly destroyed muscle layer. At 31 days of study in a group of animals with burn of the esophagus there is a certain restoration of the integrity of the mucous membrane of the esophagus, mainly with hyperplasia; there is also a decrease in the presence of leukocytes; however, there is an enlargement of the connective tissue in the submucosal membrane, which may indicate the formation of a scar. The data of the morphological description are confirmed by the morphometric parameters of the calculation of the stenosis index. With the use of extracts of beans under chemical burns esophagus conditions, improvement of the morpho-functional status of the esophagus of rats was noted: the formed connective tissue scar does not significantly affect the stenosis index (its significance is the intermediate position); the high level of leukocyte infiltration is reduced to the control parameters, which may indicate the obvious therapeutic effect of the extract of beans pods at alkaline burns of the esophagus.
The effect of some anesthetics and natural venoms on the LCС-channels functioning of the nuclear membrane of cardiomyocytes and cerebellum Purkinje neurons
Authors: Kotyk O. , Kotliarova A. , Isaeva O. , Marchenko S.
Published: February 2020

The investigation of pharmacological sensitivity of the cationic channels in nuclear membrane to the influence of anesthetics and natural venoms is relevant since it was shown that some modulators of N-cholinoreceptors (dithylinum, atracurium) affecting the large conductance cation channels (LCC-channels) functional activity are used in medicine during surgery. In addition, some injectable forms of toxins from the snake venom are used as drugs with an analgesic effect. Therefore, the aim of the study was to investigate the pharmacological sensitivity of the LCC-channels to the muscle relaxants, anaesthetics (mydocalm, diprofol) and natural venoms (neurotoxin II, α-Cobratoxin). The influence of these substances was evaluated based on changes in biophysical parameters of functioning of the LCC-channels of nuclear membrane of the cardiomyocytes and cerebellar Purkinje neurons. Ion currents through these channels were registered in the nucleus-attached or excised patch configuration and the voltage-clamp mode of the patch-clamp technique. We found that mydocalm (2 mM), diprofol (2 mM) and α-Cobratoxin (1 mM) reduced several times the probability of the channels being in the open state. Under the influence of mydocalm and α-Kobratoxin in high concentrations (1-2 mM) the effect of channels flickering was observed which indicates the channel pore blocking in its open state. At the same time, the average amplitude of the K+ current through the LCC-channels decreased by 13 % under the influence of NT II (25 μM). The results will be the basis for identification of new, more effective inhibitors of the LCC-channels that will be promising for the physiological relevance and structure of the channels investigation.
Ultrastructural changes in the vessels and capillaries of the choroid and in the retina of rats caused by a mixture of alcohols (40% ethanol and 100% methanol)
Authors: Molchaniuk N.
Published: February 2020

We was study the ultrastructure of blood vessels and capillaries of the choroid (CO), retina's pigment epithelium (RPE), it's photoreceptor cells,
ganglion cells, shoots of Muller cells of rats, that surround them, after in traperit one alinjection of a mixture of alcohols (40% ethanol and 100%
methanol) in a 3:1 ratio and separately pure methanol (the methanol dose in each group was 0.75 g/kg rat body weight) in a PEM-100-01 electron microscope (Ukraine) in the period from 1 h10 min to 14 days after the alcohols injection. It was shown that the most sensitive structures to the toxic effect of a mixture of alcohol swere endothelial cells of CO and RPE cells. Pathological changes in RPE cells consistin alteration of mitochondria, in destructi on of the elements of the smooth endoplasmic reticulum and other organelles, in alignment of folds on the basal side of the cell sand in the destruction of apical microvilli. Significant destructive changes in its cells were not as early as 1 h10 min after ijection. In the dynamics of the study 1 h 10 min to 14 days the phenomenon of hydropic dystrophy and elements of destruction of organelles in the studied cells gradually progressed with simultaneous enhancement in the cells of the compensatory-restorative processes. After the injection of pure methanol, pathological changes in the chronic retinal area and in the retina are unidirectional except for the first 3 hours. Ethanol potentiates the toxic effect of methanol in the initial observation terms and leads to deeper damage to the rat CO and RPE ultrastructure. The leading place in the amplification of pathological changes in the investigated structures, after injection of the alcohols' mixture, is given to methanol.
Teichoic acid differentially modulates TLR4 expression in sensitive and resistant to cisplatin
Authors: Senchylo N. , Gorbach O. , Dubovtseva L. , Skachkova O. , Yakovlev P. , Skaterna T. , Drobot L. , Garmanchuk L.
Published: February 2020

The Toll-like receptor family plays crucial role in the innate immune system, recognizing the molecular structures associated with pathogens derived from different microbes. TLRs also recognize the molecular structures associated with damage associated with certain diseases, such as cancer. They can either promote tumorigenesis, or suppress it. Besides, the promotion of the tumor cells growth may be associated with the acquisition of drug resistance. The data on the TLR4 expression level changes during this pathological process are controversial. That is why the purpose of our study was to determine the expression level of TLR4 in cisplatin-sensitive and cisplatin-resistant lung cancer cells. Cells line NCI-H69 (human small cell lung carcinoma) and a drug resistant subline of NCI-H69/CPR were used to determine the expression level of TLR4.Incubation of cells with teichoic acid (1 μg / ml) was performed under standard conditions for two days. The level of TLR4 expression in the cell was determined with RT-PCR at 7500 Real-Time PCR Systems ("Applied Bіosystems", USA) and specific primers and asymmetric cyan cationic fluorochrom SYBRGreen (С32Н37N4S+) with spike of consumption at λmax = 488 nm and fluorescence at λmax = 522 nm. It was shown that TLR4 expression level was almost two times lower in WT H69 cells compared with H69 cells resistant to cisplatin. In contrast,
teichoic acid oppositely influenced TLR4 expression level: increased by 1.3-times in WT H69 cells whereas decreased 4-times in H69 cells resistant to cisplatin compared with corresponding control samples without teichoic acid. In cisplatin-resistant lung cancer cells found high expression of TLR4 can be inhibited by addingteichoic acida ligand to TLRs.
Computer Literacy Skills of Public Library Users in Trivandrum: A Case Study
Authors: Markose Soumya P.
Published: February 2020

The study aims to ascertain the computer literacy skills of users of public libraries in Trivandrum district of Kerala. The study is confined to the A-grade public libraries (under the State library council) in Urban, Semi-urban and rural areas of Trivandrum district. A questionnaire was used for collecting data. A total number of 450 questionnaires were distributed out of which 393 were returned. The study reveals that the respondents possess essential computer skills. Majority The widely used web browser is Google chrome and the social networking site is Facebook. From the study it can be seen that there isa need for equipping public libraries with new technology.
Use of YouTube by Students: A Case Study of Pondicherry University
Authors: Shimray Somipam R. , Ramaiah Chennupati K.
Published: February 2020

This study examined the use of YouTube for educational purposes. An online questionnaire was designed using Google form and data were collected from Pondicherry University students. Data screening, validity and reliability were carried out before analysis with the help of SPSS software. AMOS version 22 and SPSS version 20 were used for data analysis. An independent samples t-test and one-way ANOVA test reveal that there is a significant difference between age and purpose of viewing videos (p-value = 0.003), similarly between gender and learning motivated by educational videos from YouTube (p-value = 0.001) and between gender and educational outcome (p-value = 0.005). The findings of this study show that educational videos from YouTube aided the students in preparing assignments, presentations and seminars. Also, it helps them to achieve a better educational outcome.
Research Landscape/Performance of India during 2010-2018: An Exploration through Scopus
Authors: Das Arijit , Bhattacharya Udayan
Published: February 2020

Presently total number of universities in the country is 907, (UGC (n.d.)) and these universities vary in terms of number of publications they produce. This study aims to identify the leading research institutions in India. To measure the performance of leading institutions multiple indicators have been applied, such as number of publications, total and average citations received, etc. IISc. Bangalore (15,948) produced most number of papers and BARC (32.21) received highest average citations per paper. BARC, CSIR India and University of Delhi had overall good performance in all the categories taken for the measurement.
Forecasting of the impact of acidity on the content of mobile forms of potassium in the soils of forest-steppes of Ukraine
Authors: Kucher Larisa
Published: February 2020

The level of soil acidity (рН) has the significant impact on availability of potassium to plants. For almost the century, scientists have discussed the issue of acidity of soils. Till nowadays, it is known, that carriers of potential acidity are Н+ and АІ3+ ions, which are situated in the solid phase of soil in the exchanged and absorbed state, but soil solution is acidified as a result of exchange reactions during increase of concentration of electrolytes in it (for example, during application of fertilizes the soil). Our task was to explore the impact of acidity of soil solution on the movement of potassium in some soils of forest-steppes of Ukraine: typical chernozem, podzolized chernozem and meadow chernozem. In the laboratory conditions the soil samples were influenced by citrate-phosphate-borate buffer solution of different volumes of рН – from 2.8 till 9.5 units, and the potassium content was determined by flame photometry. Based on the research results, there were created mathematical models which predict the potassium content when changing soil acidity. An exponential functional relationship between potassium content in the soil solution and its pH is established. This functional dependence allows to predict the levels of transition of potassium to the soil solution in the conditions of lowering the pH.
HIGIENE PENJAMAH DAN SANITASI PENGELOLAAN MAKANAN DI INSTALASI GIZI RUMAH SAKIT UMUM DAERAH GAMBIRAN KOTA KEDIRI
Authors: Chantika Iqdhana , Sumardianto Dadiek , Sumaningrum Ningsih Dewi
Published: February 2020

Abstract: This study aims to identify the hygiene and sanitation of food processing in the Installation Nutrition Regional General Hospital Gambiran Kediri. This type of research is descriptive observational. The study population was food handlers in the Installation Nutrition totaling 29 respondents composed of 20 food processors and renderers 9 lodging in Graha Wijaya Kusuma. By using sampling techniques was obtained total number of samples, namely 29 respondents. Installation of Nutrition showed that in hospitals Gambiran of Kediri in the category qualify yet because there are still 20.7% handlers who had suffered from typhoid and tuberculosis suspect 3.4%, 100% handlers do not have a course certificate hygiene and sanitation, 3.4% handlers who did not have a medical examination and medical examination of books and 44.8% handlers have never been vaccinated, 91.4% food management in the category qualify, as well as 95% of food processing equipment in the category qualify. Rate food hygiene and sanitation of food in hospitals Gambiran Nutrition Installation of Kediri conducted by Ministry of Health of the Republic of Indonesia. No.1096 / Menkes / Per / VI / 2011 on Sanitation Hygiene Hospitality.Keywords: hygiene of food handlers, food sanitation, hospitalsAbstrak: Penelitian ini bertujuan untuk mengidentifikasi higiene dan sanitasi pengelolaan makanan di Instalasi Gizi Rumah Sakit Umum Daerah Gambiran Kota Kediri. Jenis penelitian yang digunakan adalah deskriptif observasional. Populasi penelitian ini adalah penjamah makanan di Instalasi Gizi berjumlah 29 responden terdiri dari 20 orang pengolah makanan dan 9 orang penyaji khusus di Graha Wijaya Kusuma. Dengan menggunakan teknik total sampling diperoleh jumlah sampel, yaitu 29 responden. Menunjukan bahwa pada Instalasi Gizi RSUD Gambiran Kota Kediri dalam kategori belum memenuhi syarat karena masih ada 20,7% penjamah yang pernah menderita penyakit tipus dan 3,4% suspect TBC, 100% penjamah tidak memiliki sertifikat kursus higiene sanitasi, 3,4% penjamah yang tidak melakukan pemeriksaan kesehatan dan tidak memiliki buku pemeriksaan kesehatan serta 44,8% penjamah belum pernah divaksinasi, 91,4% tempat pengelolaan makanan dalam kategori memenuhi syarat, serta 95% peralatan pengelolaan makanan dalam kategori memenuhi syarat. Penilaian higiene makanan dan sanitasi pengelolaan makanan di Instalasi Gizi RSUD Gambiran Kota Kediri dilakukan berdasarkan Peraturan Menteri Kesehatan Republik Indonesia. No.1096/MENKES/PER/VI/2011 tentang Higiene Sanitasi Jasa Boga.Kata kunci: higiene penjamah makanan, sanitasi makanan, rumah sakit
HUBUNGAN PENGETAHUAN TENTANG MENSTRUASI DENGAN KESIAPAN DALAM MENGHADAPI MENARCHE PADA SISWI SDN ASRIKATON 1
Authors: Novitasari Silvia , Wardani Hartati Eko , Ariwinanti Desi
Published: February 2020

ABSTRACT: Menarche is the first menstruation as a natural process that occurs in the reproductive female. Menstruation is the release of the wall of the uterus (endometrium) accompanied by a reguler and normal bleeding every month from the uterus as a sign that the reproductive organs have matured. Knowledge of menstruation is crucial for female adolescent in facing menarche, so that they are ready to face menarche. Otherwise, the lack of knowledge will lead to erroneous assumptions and behavior, such as assuming that menarche is a disease, and also anxiety. The purpose of this study was to determine the correlation between knowledge of menstruation and the readiness of menarche on female adolescents at SDN Asrikaton 1, Pakis District, Malang Regency. This research used the design of Correlational research with Cross sectional approach. Samples were obtained using the technique of Total sampling the 35 female students (grade IV, V, VI) at SDN Asrikaton 1. Samples studied were female students who had not experienced menarche. Data were collected by using questionnaire, and then statistically analyzed by the methode of Chi-square. Based on the results Statistical analysis showed the significance value (p-value) of 0.000. Therefore, it can be concluded that there was a significant correlation between knowledge of menstruation and the readiness of menarche on female adolescents at SDN Asrikaton 1.Keyword: knowledge, menstruation, menarche, readiness    ABSTRAK: Menarche adalah menstruasi pertama yang merupakan proses alami yang terjadi pada wanita reproduktif. Menstruasi adalah pelepasan dinding rahim (endometrium) disertai perdarahan secara teratur dan normal yang terjadi setiap bulan dari rahim sebagai tanda bahwa organ reproduksi telah matang. Pengetahuan yang baik terkait menstruasi sangat diperlukan siswi dalam menghadapi menarche, agar mereka siap menghadapi menarche. Jika tidak, akan menimbulkan anggapan yang keliru terkait menarche, seperti menganggap bahwa datangnya menarche sebagai suatu penyakit, sehingga menimbulkan kecemasan. Tujuan dari penelitian ini adalah untuk mengetahui hubungan pengetahuan tentang menstruasi  dengan kesiapan dalam menghadapi menarche pada siswi SDN Asrikaton 1 Kecamatan Pakis Kabupaten Malang. Penelitian ini menggunakan desain penelitian korelasional dengan pendekatan cross sectional, menggunakan teknik total sampling pada 35 siswi kelas IV, V, VI SDN Asrikaton 1 yang belum mengalami menarche. Pengumpulan data menggunakan kuesioner dengan analisis data yaitu univariat dan bivariat menggunakan chi square. Berdasarkan hasil penelitian didapatkan nilai p-value 0,000. Hasil ini menunjukkan adanya hubungan yang signifikan antara pengetahuan mengenai menstruasi dengan kesiapan dalam menghadapi menarche pada siswi SDN Asrikaton 1.Kata Kunci: pengetahuan, menstruasi, menarche, kesiapan
HUBUNGAN FAKTOR RIWAYAT DIABETES MELLITUS DAN KADAR GULA DARAH PUASA DENGAN KEJADIAN DIABETES MELLITUS TIPE 2 PADA PASIEN USIA 25-64 TAHUN DI PUSKESMAS KENDAL KEREP KOTA MALANG
Authors: Gayatri Rara Warih
Published: February 2020

Abstract: Diabetes mellitus (DM) is one of the systemic diseases that manifests in the oral cavity. One effort to prevent type 2 diabetes is through surveillance activities to determine the associated risk factors. The purpose of this study was to determine the relationship of risk factors for history of diabetes mellitus and fasting blood sugar levels with the incidence of type 2 diabetes mellitus at Puskesmas Kendal Kerep in Malang City. This study used a quantitative descriptive method with cross-sectional design and was conducted at the Puskesmas Kendal Kerep in Malang City, April 2017. The sampling method used was the quota sampling method with the measured variables:  the prevalence of diabetes mellitus, a history of diabetes mellitus and levels fasting blood sugar. Data collection techniques used were interview and measurement of fasting blood sugar levels. The research instrument used were Glucko Blood Meter devices and questionnaires. Data processing includes the process of editing, coding, scoring, data entry and cleaning. Data analysis used were univariate and bivariate. The conclusion of the study is that there is a significant relationship between history of Diabetes Mellitus and GDP levels with type 2 DM.Keywords: History of Diabetes Mellitus, Fasting Blood Sugar Levels, Type 2 Diabetes MellitusAbstrak: Diabetes Melitus (DM) merupakan salah satu penyakit sistemik yang bermanifestasi dalam rongga mulut. Salah satu upaya untuk mencegah DM tipe 2 adalah melalui kegiatan surveilans untuk mengetahui faktor resiko yang terkait. Tujuan penelitian ini untuk mengetahui hubungan faktor resiko riwayat diabetes mellitus dan kadar gula darah puasa dengan kejadian diabetes mellitus tipe 2 di Puskesmas Kendal Kerep Kota Malang. Penelitian ini menggunakan metode deskriptif kuantitatif dengan desain potong lintang (cross-sectional) dan dilakukan di Puskesmas Kendal Kerep Kota Malang, Bulan April 2017. Metode sampling yang digunakan merupakan metode quota sampling dengan variable yang diukur adalah kejaidan diabetes mellitus, riwayat diabetes mellitus dan kadar gula darah puasa. Teknik pengumpulan data menggunakan wawancara dan pemeriksaan kadar gula darah puasa. Instrumen penelitian menggunkan kuesioner dan alat Glucko Blood Meter. Pengolahan data yang dilakukan meliputi proses editing, coding, scoring, entry data dan cleaning. Analisa data dilakukan dengan analisis statistic univariat dan bivariat. Kesimpulan penelitian adalah terdapat hubungan yang signifikan antara riwayat DM dan kadar GDP dengan DM tipe 2. Kata kunci: Riwayat Diabetes Melitus, Kadar Gula Darah Puasa, Diabetes Mellitus Tipe 2
'This is VJY, Over'
Authors: Bandias Susan Elizabeth , Mason Elizabeth (Janie)
Published: February 2020

This paper examines the relationship between the use of High Frequency (HF) radio and the development of social capital in the Northern Territory (NT) of Australia. Social capital is an elusive concept. It has its origin in a number of disciplines and, as a consequence, it is a mix of disparate and intangible concepts such as trust, reciprocity, norms and cooperation. It has been argued that there is a strong positive correlation between the acquisition of social capital and social and economic wellbeing. In order to determine if the use of HF radio promoted the development of social capital, qualitative data was collected from 32 NT self-identified HF radio users. Although manned operations of the Darwin-based HF coastal radio service ceased on 30 June 2002, the evidence indicates that HF radio was instrumental in the development of a sense of community amongst its widely dispersed and isolated users. The social capital outcomes of HF radio use that included social and economic well-being, engagement in participatory democracy and the acquisition of human capital were precipitated by the shared community concept of trust, informal and formal networks and cross-cutting ties.
Benefiting from Asia’s Technology Revolution [Invited Paper]
Authors: Lord John
Published: February 2020

An invited paper, the Charles Todd Oration 2019, delivered by Mr John Lord AM that covers how Australia might benefit from Asia’s technology revolution.