bluuebunny/crossref_metadata_2025 huggingface dataset:
Narrative Imagination of Islam in Nusantara: A Study on Islam in Babad Tanah Jawi and Babad Giyanti
Authors: Achmad Fawaid  , Wening Udasmoro  , Sri Margana  , Miftahul Huda
Published: October 2023

The lack of research on literary elements in "babad" is in line with the limited study of Islamic elements within this genre. This research aims to analyze the Javanese poets' depictions of Islam in "Babad Tanah Jawi" and "Babad Giyanti." The study operates under the assumption that "babad" as literary works can allegorically create a contested space where Islam interacts with other traditions. A qualitative paradigm with a comparative structural approach is employed in this study, focusing on the narratives that shape the author's understanding of Islam in the 18th century. The findings of this research reveal that the court poet's portrayal of Islam in "Babad Tanah Jawi" shares similarities with another work in the same genre, "Babad Giyanti." These commonalities encompass the utilization of Islamic verses in the "bhabuka" text and "asmaul husna," the depiction of "walisongo's" role, the practice of "tawajjuh," moral Islamic teachings, and the political positioning characterized by ambivalence and negotiation among different traditions.
Psychoanalytic Approach and Dreams Interpretation in Surah Yusuf
Authors: Al Areqih Rashad
Published: October 2023

This study examines specific concepts of the psychoanalytic approach related to dream interpretation and defense mechanisms within Surah Yusuf in the Holy Quran. These concepts are reevaluated from an Islamic perspective, based on the teachings of the Quran and the Sunnah of Prophet Muhammad. This article aims to discuss the psychoanalytic approach in Surah Yusuf from an Islamic viewpoint and how these concepts can be interpreted in the context of providing solace to Prophet Muhammad during challenging times. Specifically, this research investigates the tumultuous journey of Yusuf, his psychological suffering, and traumatic experiences, as well as how the Quran portrays dream interpretation and defense mechanisms in Surah Yusuf as an example of Prophet Muhammad in endurance and patience during his mission. The findings of this study contribute to a deeper understanding of psychoanalytic concepts, particularly dream interpretation and defense mechanisms, within the framework of a realistic and accurate Islamic perspective. The Islamic perspective demonstrates a strong balance between dreams and their interpretation tools, as well as between unconsciousness and defense mechanisms, ultimately fostering security, peace, and the ability to overcome traumatic experiences for individuals who hold firmly to faith and religious principles.
The Veil: A Phenomenon of Urban Society and Religious Identity
Authors: Surawan Surawan , Najib Kailani  , Muslim Aziz
Published: October 2023

The veil, often perceived as a simple piece of clothing, holds complex meanings within urban society, serving as both a social phenomenon and a potent religious symbol. This article delves into the intricate dynamics of the veil within the context of contemporary urban life. It explores the dual nature of the veil, where it is not merely a garment but also a profound symbol of religious identity, modesty, and devotion. By examining the urban context, this research provides insights into how the veil is embraced, interpreted, and experienced by diverse communities residing in cities. The article discusses the complex social, cultural, and religious dynamics surrounding the veil and highlights its role in shaping personal and collective identities. Furthermore, it explores the challenges and debates faced by urban communities in accommodating the diversity of veiling practices and their implications for social cohesion and integration. This study offers valuable insights into the broader discourse on religious expression and cultural diversity within urban environments, emphasizing the need for a deeper understanding of the significance of the veil in contemporary society.
EUFOREA/EPOS2020 Statement on the Clinical Considerations for CRSwNP Care
Authors: Fokkens Wytske , Hellings Peter , Alobid Isam , Anselmo-Lima Wilma , Bernal-Sprekelsen Manuel , Bjermer Leif , Caulley Lisa , Chaker Adam , Constantinidis Jiannis , Conti Diego M. , E. De Corso , Desrosiers Martin , Diamant Zuzana , Gevaert Philippe , J Han Han. , Heffler Enrico , Hopkins Clair , Landis Basile , Lourenço Olga , Lund Valerie , Luong Amber , Mullol Joaquim , Peters Anju , Philpott Carl , Reitsma Sietze , Ryan Dermot , Scadding Glenis , Senior Brent , Tomazic Peter , Toskala Elina , Zele Thibaut van , Viskens Sofie , Wagenmann Martin
Published: October 2023

Following the European Forum for Research and Education in Allergy and
Airway Diseases (EUFOREA) treatment algorithm for chronic rhinosinusitis
(CRS) with nasal polyps (CRSwNP), patients suffering from severe
uncontrolled CRSwNP are recommended to receive oral corticosteroids,
(revision) sinus surgery, systemic biologicals, and/or aspirin treatment
after desensitization (ATAD). Given the major differences in
indications, outcomes, practical considerations, risks and costs of
these key pillars of treatment, there is a growing need to define
criteria for each treatment option and list the clinically relevant and
major considerations for them. This EUFOREA document therefore provides
an expert panel overview of the expected outcomes, specific
considerations and (contra)indications of the five major treatment arms
of severe uncontrolled CRSwNP: oral corticosteroids, primary and
revision sinus surgery, biological treatment, and ATAD. This overview of
treatment considerations is needed to allow physicians and patients to
consider the different options in the context of providing optimal and
personalized care for severe uncontrolled CRSwNP. In conclusion, the
five major treatment options for severe uncontrolled CRSwNP have
intrinsic advantages, specific indications, and considerations that are
of importance to the patient, the physician, and the society. This
EUFOREA statement supports the unmet need to define criteria for the
indication of every treatment pillar of CRSwNP.
Plasmon AgNPs/MoS2/ZnO nanorods array ternary heterojunctions enabling high-efficiency solar-light energy utilization for photocatalysis and recyclable SERS detection
Authors: Yang Jingying , Chen Sixuan , Pan Mingfei , Ding Yumei , Wang Shuo
Published: October 2023

Surface-enhanced Raman scattering (SERS) has gained widespread use in
molecule-level detection benefiting from its high sensitivity and
capacity for providing molecular fingerprint information. However, the
strong adhesion of target molecules to the substrate inherently hinders
the reusability of SERS substrates. In this study, a recyclable
SERS-active substrate was facilely fabricated by anchoring silver
nanoparticles (AgNPs) at the MoS2 nanosheet edges decorated on ZnO
nanorod arrays (NRAs). This innovative design exhibited a remarkable
SERS enhancement factor (EF) of 4.6 × 107 and demonstrated significant
solar photocatalytic efficiency. Such superior features of ternary
plasma heterojunction were ascribable to the cooperative effect of the
“Schottky barrier” and “hot spots” between MoS2 and AgNPs, the
chemical enhancement proficiency inherent of the MoS2/ZnO NRAs
heterojunction, as well as the ultrafast electron transfer within the
ternary heterojunction. The developed ternary heterojunction substrate
enabled highly sensitive SERS detection of trace amounts of organic
pollutants. Moreover, this SERS substrate exhibited self-cleaning and
recyclability through solar-light-driven photocatalysis. This
bifunctional recyclable SERS substrate proved capable of meeting various
requirements for routine monitoring of environmental organic pollutants
and provided a robust avenue for the advancement of energy utilization
materials that serve as high-performance SERS sensors and catalysts.
Effectiveness of prophylactic HPV vaccine for cervical abnormalities and HPV infection in Japan: the Japanese Human Papillomavirus Disease Education and Research Survey (J-HERS) 2021
Authors: Sasagawa Toshiyuki , Saeki Yoshihiko , Irie Takuya , Itoh Fujiko , Enatsu Akiko , Komura Hiroko , Fujii Miho , Fujii Ryota , Hidaka Natsuko , Maehama Toshiyuki , Shirasu Nobuhiko , Waseda Tomoo , Shibata Takeo , TAKATA EMI , Mibe Kazuki , Sakamoto Jinichi , Yamada Sousuke , Takakura Masahiro
Published: October 2023

Objective: This study investigated the efficacy of the
prophylactic human papillomavirus (HPV) vaccine started at 2009- 2013 in
Japan. Materials and Methods: The study involved 1529 eligible
women aged 16 to 39 years who visited 11 outpatient clinics for various
reasons in Japan. All these patients underwent an examination of HPV
genotype and a Pap test using cervical cell samples. Two hundred
ninty-nine women (19.6%) received the prophylactic HPV vaccine
(bivalent :quadrivalent vaccine ratio = 2:1). Of the 5062 participants
in the Japanese Human Papillomavirus Disease Education and Research
Survey (J-HERS 2011), which was conducted in the pre-vaccination era,
3236 eligible participants were included as controls. Results:
In the present study (J-HERS 2021), highest rate for HPV vaccination
(53%) was observed in 22- to 27-year-old patients. Vaccinated ones
showed 49% protection against low-grade intraepithelial lesions (LSIL)
and atypical squamous cells not excluding high-grade squamous
intraepithelial lesions (ASCH) or worse (LSIL/ASCH+), and 100%
protection against high-grade squamous intraepithelial lesions (HSIL) or
worse (HSIL+). The prevalences of HPV16 and HPV18 infections also
significantly decreased (HPV16; 95% and HPV18; 100%), but there were
no differences in HPV6 and HPV11 infections by the vaccination. The
prevalences of HPV51 and HPV59 increased with vaccination, although
these changes were not confirmed in the comparative study with J-HERS
2011. Comparisons between the pre-vaccination period (J-HERS 2011) and
post-vaccination period (J-HERS 2021) revealed reduction rates of 43%,
51%, 88%, and 62% were observed for HPV16, HPV18, HPV16/18, and
HPV31/58 infections, respectively. Similarly, reduction rates of 62%
and 71% for LSIL/ASCH+ and HSIL+, respectively. The reduction rate for
LSIL/ASCH+ was 88% in 16- to 21-year-old patients, whereas the rate for
HSIL+ was 87% in 28- to 33-year-old patients. C onclusion:
Bivalent or quadrivalent vaccines provided 100% protection against
high-grade squamous cell lesions (suggestive of CIN2 or CIN3) in young
women aged < 39 years at 9 to 12 years after initiation of the
first nationwide HPV vaccination program in Japan. Cross-protection
against HPV31 and HPV58 is likely to occur, although some HPV type
replacements are inconsistent across vaccination regimens. This
demonstrates a high effectiveness of HPV vaccine. In contrast, we worry
about no reduction of cervical cancer in younger generation (born in
1997-2007) who are rarely vaccinated due to long term suspension of this
vaccine recommendation in Japan.
Have the cake and eat it too: a case of a technological miracle?
Authors: Avitall Boaz
Published: October 2023

1. Using the Farapulse pulse configuration and ablation procedure
results in a significant esophageal temperature increase that is
underestimated using the Circa probe and it is likely significantly
higher temperature can be recorded at close proximity to the ablation
electrodes. 2. A near-field tissue ablation is a mix of irreversible
electroporation and thermal injury. 3. The bipolar energy delivery using
the Farawave-catheter limits the field and thermal ablation to close
proximity to the bipolar ablation electrodes limiting the impact on
extracardiac tissues. 4. In the two published papers accompanying this
editorial, the Farapulse PFA technology is shown to have no short or
long-term adverse effect on the esophagus. However, reported phrenic
nerve conduction stunning may occur (7,8). It is also noted that while
Meininghaus et al. reported significant esophageal acute injuries using
RF and Cryo no long-term data is provided that these findings resulted
in long-term disabilities. 5. PFA is hampered by the inability to
adequately assess irreversible lesion formation in real-time. 6. The
advantage provided by using PFA ablation technology is added safety and
faster procedure time. These conclusions need further affirmation when
the technology is widely used.
Spinal Cord Compression Resulted from Hydatid Disease: A Brief Clinical Repot and Literature Review
Authors: Bai Ruijun , Ma Bing , Zhang Haihong , Luo Zhiqiang
Published: October 2023

Hydatid disease is an infectious disease caused by echinococcus
granulosus which mainly caused liver and lungs damaged in humans. Bone
involvement is rare and accounts for only 0.5%-4% in hydatid disease,
spine is more prone to be infected with a proportion of 50% in
musculoskeletal tissue. We present a case of spinal hydatidosis in a
47‑year‑old male presenting with low back pain radiating to the legs,
progressive weakness and hypaesthesia in the lower limbs accompanied
with difficulty walking. Computed tomography (CT) images showed a spinal
hydatid cyst in lumbar vertebra2 and caused bone destruction of the
vertebral body and lamina. Magnetic resonance imaging (MRI) images
showed hyperintense cystic components on lumbar vertebra2 with the
appearance of a lobulated, multiocular, septated cystic mass and
compressing of the spinal cord at segments lumbar vertebra1-2. The
patient underwent subtotal vertebral resection to completely remove the
damaged vertebral and paravertebral cysts, and histopathological
examination showed the characteristic features of hydatid cysts. The
patient received antiparasitic drugs treatment post-operation. The
surgical removement combined with antiviral drugs is an effective way to
treat spinal hydatidosis.
RSV disease burden in Primary Care in Italy: A Multi-Region Pediatric study, winter season 2022-23
Authors: Scarpaci Michela , Bracaloni Sara , Esposito Enrica , Angelis Luigi De , Baglivo Francesco , Casini Beatrice , Panatto Donatella , Ogliastro Matilde , Loconsole Daniela , Chironna Maria , Pariani Elena , Pellegrinelli Laura , Pandolfi Elisabetta , Croci Ileana , Rizzo Caterina , Group RSVComNet Italy Working
Published: October 2023

Introduction: Human respiratory syncytial virus (RSV) is one of the most
frequent causes of respiratory infections in children under five years
of age, but its socio-economic impact and burden in primary care
settings is still little studied. Methods: During the 2022/23 winter
season, 55 pediatricians from five Italian regions participated in our
community-based study. They collected a nasal swab for RSV molecular
test from 650 patients under the age of 5 with Acute Respiratory
Infections (ARIs) and performed a baseline questionnaire. The clinical
and socio-economic burden of RSV disease in primary care was evaluated
by two follow-up questionnaires completed by the parents of positive
children, on day 14 and 30. Results: RSV laboratory-confirmed cases were
37.8% of the total recruited ARI cases, with RSV subtype B accounting
for the majority (65.4%) of RSV-positive swabs. RSV-positive children
were younger than RSV-negative ones (median 12.5 vs 16.5 months). The
mean duration of symptoms for all children infected by RSV was 11.47 ±
6.27 days. We did not observe substantial differences in clinical
severity between the two RSV subtypes, but RSV-A positive patients
required more additional pediatric examinations than RSV-B cases. The
socioeconomic impact of RSV infection was considerable, causing 53% of
children to be absent from school, 46% of parents to lose working days
and 25% of families to incur extra costs. Conclusions: Our findings
describe a baseline of the RSV disease burden in primary care in Italy
before the introduction of upcoming immunization strategies.
The Prevalence of Burnout in a Pediatric Hematology/Oncology/BMT Division and Initiatives to Improve Workplace Wellness
Authors: Gonzalez Alyssa A. , Chao Karen , Morin Jocelyn , Zhang Jian , Yan Ke , Hoag Jennifer
Published: October 2023

OBJECTIVE: This wellness program sought to identify the
prevalence of burnout in a pediatric hematology/oncology/blood and
marrow transplantation (BMT) center and to tailor workplace wellness
initiatives to support staff. METHODS: Providers and staff from
a pediatric hematology/oncology/BMT center were invited to complete an
anonymous survey that included items from the Maslach Burnout Inventory
for Medical Personnel (MBI-MP) and author-developed questions to assess
burnout and helpfulness of program initiatives. Analyses included
descriptive and inferential statistics. RESULTS: Just over half
of respondents endorsed high risk of burnout. Advanced Practice
Providers (APPs), Registered Nurses (RN)/Care Partners (CP), and the
Oncology and Multiple specialties (individuals serving multiple
specialties [i.e., oncology and BMT]) had the largest
proportions of individuals at high risk of burnout. Inpatient nurses and
those who have worked in the division for 1-5 years endorsed greater
risk of burnout compared to their counterparts. Most respondents
reported all initiatives were somewhat to very helpful, with initiatives
aimed at bereavement support rated as most helpful.
CONCLUSIONS: Our wellness program continues to refine the
initiatives offered to align with our purpose of increasing engagement,
reducing burnout, and improving staff retention. While the benefits of
programming targeting individual level drivers of burnout should be
highlighted, the critical state of burnout requires leadership support
and engagement in wellness efforts to advance wellness culture in the
medical field beyond the limits of individual level interventions alone.
Animal models in Epilepsy
Authors: G Jefry Winner , Natarajan Anusha
Published: October 2023

Epilepsy, characterized by recurrent seizures, encompasses various
complex syndromes with varied origins. To unravel the intricate biology
of epilepsy and explore novel Antiseizure treatments, researchers have
developed over 100 in vitro and in vivo epilepsy models, each simulating
different seizure types. These experimental models serve as
indispensable tools for investigating the neurochemical,
neurophysiological, cellular, and molecular mechanisms governing
epileptic seizures, offering a comprehensive understanding of this
condition. This article provides a comprehensive overview of diverse
experimental models crucial for studying Antiseizure Medication and
seizures, including Generalized Tonic-Clonic Seizure (GTCS), Temporal
Lobe Epilepsy (TLE), Absence Seizure, Myoclonus, and Status Epilepticus
(SE) Models. Researchers leverage these models to gain critical insights
into epilepsy’s underlying causes, available therapies, and potential
therapeutic targets. The study digs into a thorough analysis of the
benefits and drawbacks related to various chemical models used in
epilepsy treatment. This dual approach adds to the continuing discussion
in epilepsy research by clarifying the complicated issues surrounding
therapeutic strategies and improving our understanding of the complexity
of epilepsy. This article includes discusses GTCS, SE, and TLE subtypes
such as WAG/Rij rats, coriaria lactone-induced TLE, pilocarpine-induced
TLE, Tottering 6j mouse, GHB-induced seizure model, PTZ-induced model,
NMDA-induced seizure models, and flurothyl-induced seizure model.
Penicillin-induced TLE, Theiler’s virus-induced TLE, and many more.
Mitophagy and ferroptosis in cerebral ischemia-reperfusion: regulatory mechanisms and therapeutic potential
Authors: li haoxiu , Cheng Zhongqiang , Bi Meng , shi jing , xu huiling , Li weirong
Published: October 2023

Nutrient deficiency, excitotoxic injury, and oxidative stress caused by
cerebral ischemia/reperfusion injury are important inducing factors of
mitophagy and ferroptosis in neurons. Ferroptosis is an iron-dependent
mode of cell death usually accompanied by a large accumulation of iron
ions and lipid peroxides. Mitophagy is one of the forms of selective
autophagy, which can maintain mitochondrial and cellular homeostasis by
eliminating dysfunctional mitochondria. Mitophagy and ferroptosis are
closely related to the pathological mechanism of ischemia/reperfusion
injury. However, the function and mechanism of mitophagy in regulating
ferroptosis are only beginning to be understood, and the relationship
between mitophagy and ferroptosis after cerebral ischemia/reperfusion
has not been elucidated. This article reviews the mechanism pathways of
mitophagy and ferroptosis after cerebral ischemia/reperfusion,
especially discusses the common regulatory factors of mitophagy and
ferroptosis in cerebral reperfusion injury, and focuses on the
therapeutic potential of mitophagy in regulating ferroptosis, in order
to provide ideas for targeted treatment of cerebral ischemia/reperfusion
injury.
Transition from acute kidney injury to chronic kidney disease: the role of tubular epithelial cells, macrophages and the crosstalk between them
Authors: Shu Huapan , Sun Lulu , Tu Yuchi , Liao Qianqian , Feng Li , Ren Ming , Yao Lijun
Published: October 2023

Acute kidney injury (AKI) is a common disease characterized by a sharp
decline of kidney function within a short time and is associated with
high morbidity and mortality in recent years. Although the development
of clinical therapy for AKI has taken a certain degree of effect, these
treatments do little to improve the prognosis of patients suffering from
AKI. Mounting researches have demonstrated that AKI is an independent
and important risk factor for chronic kidney disease (CKD), and the
transition from AKI to CKD involves various mechanisms. Recently, in
addition to the pathophysiology of tubular epithelial cells (TECs) and
macrophages aberrant polarization, the crosstalk between them has
garnered significant attention after kidney injury. The crosstalk
between TECs and macrophages polarization is closely related to
inflammation, repair and fibrosis after kidney injury, which are all key
points in the transition from AKI to CKD. Exploring the progression of
AKI to CKD is of great significance for clinical treatment. Therefore,
this review aims to summarize the current researches on tubular
epithelial cells, macrophages and the crosstalk them to provide
effective reference for subsequent research and help to find potential
therapeutic targets to prevent the progression of AKI to CKD.
Enhanced product of veratramine and cyclopmine in cell suspension of Veratrum nigrum L. by elicitors
Authors: Ma Pengda , He Di , Wang Xiujuan , Wen Yashi , Feng Qiaoqiao , Ma Rui
Published: October 2023

Steroid alkaloids are the most important active substance in medicinal
plant V. nigrum, which have many pharmacological effects such as
anti-hypertension, anti-tumor and anti-insect. At present, cell
suspension culture is an effective method to produce secondary
metabolites, but the yield of secondary metabolites cultured in ordinary
cell suspension is not high. Elicitation can overcome the limitation of
low metabolite yield in plant cell culture platforms in vitro, and it is
an effective method to improve productivity. The purpose of this study
is to explore the best elicitor combination and apply it to cell
suspension of V. nigrum to improve the yield of steroidal
alkaloids. In this study, several abiotic elicitors (MeJA, SA, Co
, Cu ) and a biological elicitor
yeast extract (YE) were used to treat V. nigrum callus. Among
various treatments applied, MeJA (100 uM concentration) improved the
highest in the accumulation of two main steroid alkaloids in V.
nigrum veratramine and cyclopmine. The content of veratramine has
increased to 0.6689 ± 0.089 mg/g DW as compared to the content of
control 0.1495 ± 0.047 mg/g DW, and the content of cyclopmine has
increased to 0.3869 ± 0.040 mg/g DW as compared to the content of
control 0.3032 ± 0.031 mg/g DW. The addition of YE (200 mg/L) can
effectively improve biomass accumulation (Fresh weight (FW): 1.8035 ±
0.079 g) as compared to the content of control (FW: 1.1565 ± 0.081 g).
Subsequently, these two elicitors were applied to suspension cell
culture, and the effects of MeJA concentration, YE concentration,
inoculation amount and MeJA induction time on the total contents of
veratramine and cyclopmine produced by cell suspension were
investigated. The experimental results show that the total yield of
veratramine and cyclopmine can be increased from the initial 0.0338 ±
0.002 mg to 0.0638 ± 0.004 mg with the addition of elicitors. Through
the optimization of response surface experiment and combined with the
actual experimental conditions, the final optimal suspension cell
culture conditions were determined as follows: MeJA concentration: 120
um/L; YE concentration: 450 mg/L; Inoculation amount: 0.45 g; MeJA
induction time: the 18th day. Finally, the total yield of veratramine
and cyclopmine reached 0.0827 ± 0.003 mg under this culture condition.
It is possible to scale the current strategy to a bioreactor for higher
productivity of steroid alkaloids of interest for various pharmaceutical
industries.
Weight Loss-Independent Effect of Liraglutide on Insulin Sensitivity in Individuals with Obesity and Pre-Diabetes
Authors: Mashayekhi Mona , Nian Hui , Mayfield Dustin , K. Devin Jessica , Gamboa Jorge L. , Yu Chang , Silver Heidi J. , Niswender Kevin , Luther James M. , Brown Nancy J.
Published: October 2023

Metabolic effects of glucagon-like peptide-1 (GLP-1) receptor agonists are confounded by weight loss and not fully recapitulated by increasing endogenous GLP-1. We tested the hypothesis that GLP-1 receptor (GLP-1R) agonists exert weight loss-independent, GLP-1R-dependent effects that differ from effects of increasing endogenous GLP-1. Individuals with obesity and pre-diabetes were randomized to 14 weeks of the GLP-1R agonist liraglutide, hypocaloric diet, or the dipeptidyl peptidase 4 (DPP-4) inhibitor sitagliptin. The GLP-1R antagonist exendin (9-39) and placebo were administered in a two-by-two crossover study during mixed meal tests. Liraglutide and diet, but not sitagliptin, caused weight loss. Liraglutide improved insulin sensitivity measured by HOMA-IR, HOMA2 and the Matsuda index after two weeks, prior to weight loss. Liraglutide decreased fasting and post-prandial glucose, decreased insulin and C-peptide, and decreased fasting glucagon. In contrast, diet-induced weight loss improved insulin sensitivity by HOMA-IR and HOMA2, but not Matsuda index, and did not decrease glucose. Sitagliptin increased endogenous GLP-1 and GIP without altering insulin sensitivity or fasting glucose, but decreased post-prandial glucose and glucagon. Notably, sitagliptin increased GIP without altering weight. Acute GLP-1R antagonism increased glucose in all groups, increased Matsuda index and fasting glucagon during liraglutide, and increased endogenous GLP-1 during liraglutide and sitagliptin. Thus, liraglutide exerts rapid, weight loss-independent, GLP-1R-dependent effects on insulin sensitivity that are not achieved by increasing endogenous GLP-1.
Factores biofuncionales predisponentes de depresión en adultos mayores
Authors:   Investigadora Independiente, Salinas Velastegui Verónica Gabriela , Cruz Castillo Yessenia Magaly ,   Investigadora Independiente, Solís Serrano María Augusta ,   Investigadora Independiente, Cadena Sánchez Kléver Darío ,   Investigador Independiente
Published: October 2023

La depresión es un trastorno emocional que causa un sentimiento de tristeza constante y una pérdida de interés en realizar diferentes actividades. Se tiene que el objetivo de este artículo fue analizar los factores biofuncionales predisponentes de depresión en adultos mayores. Se realizó una revisión desde las investigaciones y se encontró que: factores biológicos se consideran la predisposición genética heredada y la presencia de otras enfermedades; entre los factores psicológicos y sociales vivir la pérdida de algún familiar o amigo, laboral, material, de salud, de funciones físicas y/o cognitivas, vivir abandono familiar, falta de redes de apoyo, viudez, y recursos económicos insuficientes. Así que este padecimiento puede ser el resultado de la combinación de los factores antes mencionados. Si bien envejecer es una parte inevitable de la vida, la depresión no debe formar parte de ella. Los investigadores están de acuerdo en que el reconocimiento, el diagnóstico y el tratamiento tempranos pueden contrarrestar y prevenir las consecuencias emocionales y físicas de la depresión.
Diagnosis dan Tata Laksana Metastasis Tulang
Authors: Cahyanur Rahmat , Salamah Thariqah
Published: October 2023

Tulang merupakan salah satu organ yang sering menjadi lokasi metastasis kanker, misalnya kanker payudara, prostat, dan paru. Metastasis tulang berpotensi memicu peningkatan mortalitas dan morbiditas, serta penurunan kualitas hidup. Gejala dan tanda klinis metastasis tulang mencakup nyeri, fraktur patologis, hiperkalsemia, serta kompresi medula spinalis. Oleh karena itu, deteksi dini dan tata laksana metastasis tulang yang tepat diperlukan untuk mencegah komplikasi lebih lanjut. Pertimbangan dalam memilih modalitas pemeriksaan radiologi, sebagai langkah utama dalam diagnosis, harus dilakukan secara rasional berdasarkan lokasi lesi metastasis tulang. Selain itu, pemeriksaan alkalin fosfatase dan biopsi juga dapat menjadi pilihan pemeriksaan penunjang. Tata laksana metastasis tulang mencakup terapi suportif, seperti kontrol nyeri, pemberian bifosfonat, pemberian denosumab atau terapi sistemik, penggunaan radiofarmaka, dan kontrol lokal, yaitu radiasi eksterna atau pembedahan.
THE IMPACT OF TAX E-FILING SYSTEM QUALITY ON TAXPAYER SATISFACTION: PERCEIVED USEFULNESS AS MEDIATOR
Authors: Muslichah Muslichah , Bashir Mohamed , Arniati Tutik
Published: October 2023

Tax e-filing system quality is vital, directly shaping tax process efficiency and user convenience. This study aims to examine the effect of tax e-filing system quality on taxpayer satisfaction using perceived usefulness as a mediating variable. To gather data, 300 questionnaires were distributed to taxpayers, resulting in participation from 230 respondents.The findings of our study demonstrated a positive effect of tax e-filing system quality on both user satisfaction and perceived usefulness, and that perceived usefulness has a positively significant effect on user satisfaction. Furthermore, this study confirmed that perceived usefulness as a mediating variable in the e-filing system quality and user satisfaction relationship. The study enhances tax system theory by revealing the mediating role of perceived usefulness, and it practically suggests improving e-filing systems for increased taxpayer satisfaction and efficient tax collection.
MARKET PERFORMANCE: THE EFFECT OF INTELLECTUAL CAPITAL AND INTELLECTUAL CAPITAL DISCLOSURE
Authors: Mukhtaruddin Mukhtaruddin , Saftiana Yulia , Riani Ely , Siska Emi Yulia , Yamaly Fadhil
Published: October 2023

Intellectual Capital is a concept which gives new knowledge-based resources and optimally describes the intangible assets utilized. It enables a company to run its strategies effectively and efficiently without revealing its intangible assets such as knowledge, relationships and image in the financial report. These attributes create differences and describe the company’s future opportunities. The research therefore illustrated how Intellectual Capital (IC) and Intellectual Capital Disclosure (ICD) influenced the Market Performance (MP) by using the purposive sampling method. The data used is secondary which was obtained from 102 service companies listed in the Indonesian Stock Exchange (IDX) and analyzed using the multiple linear regression. The result of this research showed that both IC and ICD influenced the MP. This research indicated that the signal presented by the company through ICD minimized asymmetrical information. This proved that maximum management of the IC gave some added values capable of increasing competitive advantages.
Could the Southern-Kurtalan Express be as Popular as the Eastern Express? Comparative SWOT Analysis
Authors: Yağmur Yenal
Published: October 2023

Train tourism can play a critical role in the development of the tourism potential of the cities, such as increasing the tourism potential of the cities, economic contribution, reducing the differences in the level of development between regions, and employment in the cities where the railway line passes, and thus in the development of the country’s tourism potential. This situation occurred in the cities of the route where the Eastern Express passed. Therefore, the aim of this research is to present a comparative SWOT framework on whether the Southern-Kurtalan Express has the potential to be popular like the Eastern Express, and to explore the perception and behavioral tendencies of travelers towards the Southern-Kurtalan Express. While conducting interviews with 30 participants to create a SWOT matrix for the Southern-Kurtalan Express, the SWOT matrix for the Eastern Express was compiled from the relevant literature. Comparing the data from the participants and the SWOT matrices compiled from the literature, it can be deduced that the Southern-Kurtalan Express is as strong as the Eastern Express and even has more advantages but has similar weaknesses and that the Southern-Kurtalan Express faces significant opportunities as well as similarly wider threats. In this regard, the Southern-Kurtalan Express has a high potential to be as popular as the Eastern Express, but success can be achieved if all stakeholders act together to determine strategies for reducing the threat width and improving the potential.
Bentuk Penyajian Kesenian Calempong Oguang Pada Acara Pernikahan di Sialang Kapur IX Lima Puluh Kota
Authors: Melia Septri  , Syeilendra
Published: October 2023

Penelitian ini bertujuan untuk mendeskripsikan dan menemukan tentang Bentuk Penyajian Kesenian Calempong Oguang pada Masyarakat Sialang. Jenis penelitian ini adalah penelitian kualitatif dengan pendekatan metode deskriptif analisis. Jenis data menggunakan data primer dan data sekunder. Instrument utama peneliti sendiri dan dibantu dengan instrument pendukung seperti alat tulis dan handphone. Teknik pengumpulan data dilakukan dengan cara studi pustaka, observasi, wawancara, dan dokumentasi. Langkah analisis data adalah reduksi data, display data, dan kesimpulan.
Hasil penelitian mengemukakan bahwa bentuk penyajian kesenian Calempong Oguang pada masyarakat Sialang pada acara pernikahan adalah di depan rumah menggunakan model pentas arena. Dalam acara pesta pernikahan ini disajikan pada malam hari memainkan lagu-lagu:1) Lagu Tigo-Tigo, 2) Lagu Lang lalu, 3) Lagu Sandayuang, 4) Lagu kaja bakaja dan lain-lain yang dimulai setelah selesai sholat Isya sekitar jam 08.00 WIB sampai Subuh dini hari. Penyajian Calempong Oguang yang dimainkan oleh para orang tua (laki-laki dan perempuan) yang berbentuk ansambel campuran bertujuan untuk menghibur ibu-ibu yang sedang memasak dan para tamu undangan agar dapat menghilangkan rasa penat pada waktu mempersiapkan masakan untuk besok hari H pesta perkawinan. Dengan adanya bunyi-bunyian dari lagu-lagu Calempong Oguang mampu menciptakan suasana gembira serta dapat mendekatkan hubungan silaturahmi dengan keluarga dan tamu yang datang kerumah.
Deskripsi Teknik Permainan Gitar Klasik Karya Antonio Lauro: Vals Venezolano no. 2
Authors: Waruwu Dian Kurnia Cristin , Tulus Handra Kadir
Published: October 2023

Penelitian ini bertujuan untuk mengetahui karakteristik dan teknik yang terdapat dalam lagu Vals Venezolano. No 2 Karya Antonio Lauro melalui permainan gitar klasik oleh Ana Vidovic pada video pertunjukannya tahun 2015 di gedung Asamsaal Ettlingen, Jerman. Tavi jinariu, pada akun Youtube Elite Guitarist tahun 2018. Penelitian ini bersifat deskriptif dengan pendekatan kualitatif, dalam hal ini akan mendeskripsikan, menguraikan dan menggambarkan tentang karakteristik dan teknik serta metode latihan untuk dapat menguasai tenik tersebut. Objek penelitian menjadi pusat perhatian dan sasaran penelitian adalah teknik permainan gitar klasik dalam Vals Venezolano No. 2 karya Antonio Lauro. Instrument penelitian ini yaitu peneliti sendiri dengan dibantu beberapa perangkat alat untuk mengolah data seperti, alat perekam audio dan audio visual, lembaran pencatatan dan pedoman wawancara. Jenis data menggunakan data primer diambil dari partitur Vals Venezolano No. 2 karya Antonio Lauro dan data sekunder ambil dari video rekaman dari Youtube, buku-buku atau literatur dan wawancara dengan ahli. Langkah dalam menganalisis data adalah perolehan wawancara dari narasumber, observasi dan dokumentasi. Hasil penelitian menunjukkan bahwa teknik yang digunakan pada gitar klasik karya Antonio Lauro: Vals Venezolano No. 2  yakni apoyando, tirando, harmonic, barre, slur. Karakteristik dalam lagu ini yaitu rubato, sinkopasi, hemiola, con grazia dan waltz. Dalam tekni permainan khusus Ana Vidovic menambahkan harmonic 3 dawai pada fret 12 sebagai gaya permainan penutup dari Ana Vidovic pribadi yang tidak ada tercantum pada score.
Bentuk Penyajian Tari Tobo Basampuak Oleh Sanggar Seni Sinar Tampalo di Nagari Padang Laweh Kecamatan Koto VII Kabupaten Sijunjung
Authors: Dona Evrie  , Mansyur Herlinda
Published: October 2023

Artikel ini bertujuan untuk mendeskripsikan dan menganalisis bentuk penyajian Tari Tobo Basampuak berasal dari Nagari Padang Laweh, sebuah tarian yang menceritakan kegiatan petani pada saat turun kesawah sampai panen. Jenis penelitiannya adalah kualitatif dengan pebdekatan deskriptif. Teknik pengumpulan data dilakukan dengan cara Studi Kepustakaan, Observasi, Wawancara, dan Dokumentasi. Temuan penelitian menunjukkan bahwa tari Tobo Basampuak adalah tari kreasi baru yang memiliki ragam gerak seperti, bararak masuk, mamangkua, malunyah, batanam, basiang, drama kobou mangoncah sawah, manyabik, maiyiak, maangin dan malapeh panek serta bararak keluar. Penari tari Tobo Basampuak terdiri atas 2 penari laki-laki dan 6 penari perempuan, menggunakan desain lantai horizontal dan melengkung. Tari ini memiliki desain dramatik karena dipertengahan penampilan terdapat dialog oleh penari pada saat muncul pemeran kerbau. Tari ini diiringi dendang dodou, serta alat musik talempong, tambur, gong, dan gandang. Kostum penari laki-laki berupa baju taluak balango, celana galembong, sasampiang, dan deta, sedangkan kostum perempuan berupa baju kurung basiba, songket, dan deta bacincin. Properti yang digunakan terdiri dari cangkul, sabit, niru, dan kambuik. Tempat penyajiannya ada yang di atas panggung ada pula di lapangan terbuka, dan ditampilkan setiap tahun dalam Festival Lansek Manih.
Pembelajaran Seni Budaya (Teater) di Kelas XI IPS 3 SMA Negeri 1 Lintau Buo Utara
Authors: Permata Ayunda  , Marzam
Published: October 2023

Penelitian ini bertujuan untuk mengetahui dan mendeskripsikan pembelajaran seni budaya (teater)  di kelas XI IPS 3 di SMA Negeri 1 Lintau Buo. Jenis penelitian yang digunakan adalah penelitian kualitatif dengan pendekatan deskriptif. Instrumen penelitian adalah peneliti sendiri dan di bantu dengan alat pendukung seperti alat tulis dan kamera. Teknik pengumpulan data meliputi observasi, studi pustaka, wawancara dan studi dokumentasi. Langkah-langkah menganalisis data adalah, reduksi data, penyajian data, dan kesimpulan. Hasil penelitian menunjukkan bahwa kegiatan pelaksanaan pembelajaran seni budaya (teater) di kelas XI IPS 3 SMA Negeri 1 Lintau Buo dengan menggunakan kurikulim 2013 belum sesuai dengan silabus dan Rencana Pelaksanaan Pembelajaran (RPP) yang di rancang oleh guru seni budaya (teater) di kelas XI IPS 3 di SMA Negeri 1Lintau Buo, sehingga berdampak  pada kurangnya pemahaman peserta didik tentang pementasan seni teater sesuai dengan teknik dan prosedur perancangan pementasan seni teater. Agar tercapainya tujuan pembelajaran dan hasil belajar, guru harus memperhatikan silabus dan Rencana Pelaksanaan Pembelajaran (RPP) yang telah di rancang dan dapat di terapkan pada proses pelaksanaan pembelajaran mengenai pementasan seni teater tersebut.
Pendekatan Kreatif Penciptaan Tari Anak-Anak: Tari Kipas di Sanggar Galatiak Pitameh Kota Padang
Authors: Adinda Rahmasari Putri  , Darmawati
Published: October 2023

Penelitian ini bertujuan untuk mendeskripsikan Pendekatan Kreatif Penciptaan Tari Anak-Anak: Tari Kipas di Sanggar Galatiak Pitameh Kota Padang. Jenis penelitian menggunakan metode deskriptif dari penelitian kualitatif. Objek penelitiannya tari Kipas di sanggar Galatiak Pitameh kota Padang dan difokuskan pada pendekatan kreatif penciptaannya. Teknik pengumpulan data yaitu teknik pustaka, observasi, wawancara, dan dokumentasi. Hasil penelitian menunjukkan bahwa pendekatan kreatif penciptaan tari Kipas Sanggar Galatiak Pitameh memiliki tiga tahapan, (1) Tahap eksplorasi, yaitu tahapan yang memiliki kepekaan rasa terhadap objek, dengan mendengarkan musik yang sudah dipilih sebagai musik pengiring pada tari Kipas. (2) Tahap improvisasi yaitu daya imajinasi dan daya fikir berkonsentrasi pada objek, dalam improvisas lebih luas mengembangkan daya imajinasinya yang telah didapat pada proses eksplorasi. Melakukan gerak secara spontan yang muncul dari suatu kesadaran diri sendiri, menggunakan gerakan-gerakan bebas dalam menggunakan kipas sebagai properti, dengan menunjukkan ekspresi wajah gembira. Pada tahap ini langsung dipraktekkan hasil pencarian gerak kepada penari, namun pada proses penari cilik juga memiliki daya kreatif.  Dari mereka memiliki spontan terhadap gerak yang diberikan sehingga lebih bervariasi dalam pembawaannya. (3) Tahap pembentukan yaitu, proses klimak dari tahap pembentukan yang artinya sudah selesai, mengubah bentuk gerak dari tahap-tahap sebelumnya, kemudian berusaha membentuk gerak menjadi gerakan tarian yang utuh.
Pengaruh Kepribadian Agreeableness dan Conscientiousness terhadap Academic Dishonest: Studi Empiris Mahasiswa Akuntansi Perguruan Tinggi di Kota Padang
Authors: Fahdri Aldian , Helmy Herlina
Published: October 2023

Academic dishonesty is still common among academics and is mostly done by students today and this is major concern. Accounting research needs to pay attention to this phenomenon. This study aims to analyze the effect of agreeableness and conscientiousness on academic dishonesty. This type of research is associative causality research with a quantitative approach. The population in this study were undergraduate students of Accounting, Faculty of Economics, Padang State University, Andalas University, Bung Hatta University and the Computer College Foundation, Putra Indonesia University. The number of research samples was determined using the slovin formula. The samples in this study were undergraduate Accounting students who were active at Padang State University, Andalas University, Bung Hatta University, and the University Putra Indonesia Computer College Foundation. The data collection method used a questionnaire distributed in the form of a google form. The data used in this study is primary data. The hypothesis in this study was tested using multiple linear regression analysis with IBM SPSS 25. The results showed that agreeableness and conscientiousness had a significant and negative effect on academic dishonesty.
Pengaruh Good Corporate Governance dan Kinerja Keuangan terhadap Financial Distress: Studi Empiris pada Perusahaan Subsektor Jasa Konsumen yang Terdaftar di Bursa Efek Indonesia Tahun 2017-2021
Authors: Fania Elsa , NR Erinos
Published: October 2023

This study aims to examine the effect of good corporate governance and financial performance on financial distress. This type of research is causal research with a quantitative approach. The data source used is secondary data from the annual reports of consumer services sub-sector companies listed on the Indonesian stock exchange in 2017-2021. The population in this study is the consumer service sub-sector companies listed on the Indonesian stock exchange in 2017-2021. Purposive sampling technique was used for sampling in order to obtain 105 samples. This study uses logistic regression analysis and paired sample t-test using SPSS 25. The results of logistic regression analysis show that the size of the audit committee and the proportion of independent commissioners have no effect on financial distress, while profitability and liquidity have a negative effect on financial distress. The results of the paired sample t-test show that there are differences financial distress in consumer services sub-sector companies before and after Covid-19.
Analisis Tingkat Konservatisme Akuntansi (Unconditional) Selama Masa Pendemi Covid-19: Studi Empiris pada Perusahaan yang Terdaftar di Bursa Efek Indonesia pada Tahun 2018-2021
Authors: Martasya Risa , Sebrina Nurzi
Published: October 2023

The research aims to determine whether the uncertainty of the environment caused by the Covid-19 pandemic is driving companies listed on the Indonesia Stock Exchange to implement conservative accounting principles by looking at the differences in unconditional conservatism before and during the Covid-19 pandemic. The population in this study is all companies listed on the Indonesia Stock Exchange from 2018-2021. The sample technique used is purposive sampling, there are 395 companies that are used as research samples for a total of 4 years of observation with a total of 1580 samples. The data used is secondary data obtained from the financial reports of the sample companies for the years 2018 to 2021. The data is obtained from the official website of the Indonesia Stock Exchange (BEI). The data analysis technique used is descriptive analysis, normality test, and hypothesis test using SPSS25 software. Based on the results of the research and the discussions that have been conducted, it can be concluded that the hypothesis is rejected and there is no difference in the level of unconditional conservatism before and during the Covid-19 pandemic.
Analysis of User Satisfaction Virtual Reality Tourism Kemenparekraf Using the End User Computing Satisfaction Method
Authors: Pingki Pingki , Bharata Wira
Published: October 2023

Virtual Reality (VR) has developed on the concept of tourism where people can enjoy virtual tourist destinations called VR Tourism. The tourism industry, one of which is Indonesia, is utilizing this technology development as a marketing strategy for tourist objects, one of which is VR Tourism Kemenparekraf. Previous research on how VR affects marketing has been carried out a lot, but this research will focus on user responses to VR Tourism services which are still little done. From this, by utilizing the End User Computing Satisfaction (EUCS) method, it is used to measure the satisfaction of VR Tourism Kemenparekraf users, as well as to see whether this method is still relevant to use. Respondents were determined as many as 75 people who had used VR Tourism Kemenparekraf at least once. The data was processed using SPSS software, where the research results found that all variables contained in the EUCS method had a positive effect on user satisfaction. Users are satisfied with VR Tourism Kemenparekraf. The EUCS method is still relevant for use in testing user satisfaction in VR Tourism Ministry of Tourism and Creative Economy.