bluuebunny/crossref_metadata_2025 huggingface dataset:
Complications of Paediatric Ventriculoperitoneal (VP) Shunt: Experience in A Tertiary Care Hospital
Authors: Paul Swapan Kumar , Islam Rakibul , Ghosh Paritosh Kumar , Biswas Prosanto Kumar , Hossain Delwar , Rashid Md Aminur
Published: December 2022

Background: Ventricloperitoneal (VP) shunt is the most commonly used shunt procedure in children because of the capacity of the peritoneum to resorb fluid like Cerebrospinal fluid (CSF). Primary and subsequent peritoneal catheter placement is relatively easy procedure to be done. VP shunt procedures are associated with varieties of complications.

Methods: A prospective study was done from July 2017 to June 2021 in Faculty of Paediatric Surgery, Bangladesh Shishu Hospital & Institute. A total number of cases underwent VP shunt surgery were 192. We had analyzed 82(42.71%) patients of VP shunt surgery who had various shunt related complications and analyzed the predisposing risk factors and spectrum of complications.

Results: The mean age was 16±14 months and median age was11.75 months. Out of 82 patients 56 (68.29%) were male and 26(31.71%) were female. Seventy (85.37%) patients had single complication and 12(14.63%) had more than 1 complications. Twenty four (29.27%) patients had infective complication and 58(70.73%) had mechanical complication. Infective complications (24, 29.27%) include shunt tract abscess (41.66%), CSF leak (16.67%) exposure of shunt tube through anus (16.67%), wound infection (16.67%). Mechanical complications were present in 58(70.73%) cases and 40(48.78%) had ventricular end malformation, 24(29.27%) peritoneal end and 18(21.95%) had both end malformation.

Conclusion: With this prospective study of complications of VP shunt, age at initial shunt surgery, insertion and important patient-related predictors of shunt failure. The different predominant etiological factors the interval between the age of initial shunt placement and onset of complications were the most responsible for early and late shunt failure were infective and mechanical complications respectively.

DS (Child) H J 2021; 37(2): 129-134
Pulmonary Tuberculosis: Atypical Presentation
Authors: Ratan Md Naim Hossain , Azhar Aysha , Mamun ABM Mahfuj Hassan Al , Mobarak Mohammad Reaz
Published: December 2022

Abstract not available

DS (Child) H J 2021; 37(2): 140-142
Abstracts From Current Literature Vol. 37(2)
Authors: Editor The
Published: December 2022

Abstract not available

DS (Child) H J 2021; 37(2): 143-144
Postgraduate Courses and Training in Paediatrics in Bangladesh Shishu Hospital & Institute Vol. 37(2)
Authors: Editor The
Published: December 2022

Abstract not available

DS (Child) H J 2021; 37(2): 146
Hemşirelerin profesyonel değer algısının yaşlı ayrımcılığı tutumu üzerine etkisi
Authors: Aydemir Azize
Published: December 2022

Amaç: Araştırmanın amacı hemşirelerin profesyonel değerler algılarının yaşlı ayrımcılığı tutumları üzerine etkisinin belirlenmesidir. Yöntem: Araştırmaya bir üniversite hastanesinde çalışan 207 (%98.1) hemşire katılmıştır. Verilerin toplanmasında “Hemşireleri Tanıtıcı Form”, “Hemşirelerin Profesyonel Değerler Ölçeği (HPDÖ)” ve “Yaşlı Ayrımcılığı Tutum Ölçeği (YATÖ)” kullanılmıştır. Verilerin analizinde parametrik ve non-parametrik testler yapılmıştır. Araştırmanın hemşirelerin yaşlı ayrımcılığı tutumu bağımlı değişkeni ile profesyonel değer algısı bağımsız değişkeni arasındaki ilişki Pearson korelasyon, etki ise regresyon analizi ile test edilmiştir. Bulgular: Hemşirelerin YATÖ toplam puanı (82.28±9.12) yaşlı ayrımcılığı tutumunun olumlu yönde yüksek olduğunu ve HPTÖ toplam puanı (123.42±19.97) profesyonel değer algılarının yüksek olduğunu göstermektedir. YATÖ alt boyutlarından yaşlı Yaşamını Sınırlama (32.93±4.26) alanında ve HPDÖ alt boyutlarından İnsan Onuru (44.43±7.23) alanında hemşirelerin en yüksek toplam puana sahip oldukları görülmüştür. Ayrıca hemşirelerin profesyonel değer algısı ile yaşlı ayrımcılığı tutumu arasında pozitif yönde zayıf bir ilişki olduğu (r=0.147; p=0.035>0.05) bulunmuştur. Hemşirelerin yaşlı ayrımcılığı tutumu değişkeninin %2.1’inin hemşirelerin profesyonel değer algıları ile açıklandığı tespit edilmiştir. Sonuç: Hemşirelerin mesleki değer algısı ile yaşlı ayrımcılığı tutumu arasındaki ilişki zayıftır. Hemşirelerin yüksek insan onuru ve sorumluluk değer algısına sahip olmaları, yaşlı ayrımcılığı tutumlarını olumlu yönde etkilemektedir.
Sağlık çalışanlarının yaşadığı iş yeri şiddeti
Authors: Pala Dağoğlu Nurdan
Published: December 2022

Son zamanlarda Türkiye’de ve Dünyada sağlık çalışanlarının yaşadığı şiddet artmaktadır. Bu durum hastalar, hasta yakınları ve çalışanlar arasındaki iletişimi ve güveni sarsmakta ve çalışanların iş motivasyonunu azaltmakta, hastalara sunulan hizmetin kalitesini düşürmektedir. Sağlık çalışanlarının yaşadığı iş yeri şiddeti, çalışanların kurum aidiyetini azaltmakta, sağlık çalışanlarının ruh sağlığını bozabilmekte ve işten ayrılmalarına neden olabilmektedir. Bu derlemede Türkiye’de ve dünyada sağlık çalışanlarının yaşadığı şiddet, şiddetin nedenleri ve şiddetin önlenmesine yönelik yaklaşımlar onusunda bilgi vermek ve sağlık çalışanının yaşadığı iş yeri şiddetine dikkat çekmek amaçlanmaktadır.
Fizyolojik doğum savunucuları: Türk ebelik öğrencilerinin doğal doğum algıları
Authors: Bilgiç Fatma Şule , Karaahmet Aysu Yıldız , Güdücü Neriman
Published: December 2022

Objective: The aim of this study is to examine the views of students studying in the midwifery department about the perception of birth. Method: A cross sectional descriptive study. The study was carried out using an online questionnaire, which was prepared by researchers in accordance with the current literature, evaluating students' perception of childbirth. Results: 484 undergraduate midwifery students (mean age, 20.94±2.35 years) agreed to participate in the study. Approximately 90% of the students reported that they have heard the concept of natural birth. The findings showed that 61% of the students have heard the term of natural birth at the university. The percentages of students who disagree with the presence of the freedom of movement of a pregnant woman, the usefulness of music, bath and massage at birth, the effectiveness of relaxation techniques or entering to water at the body temperature at birth, supporting to other birth positions instead of supine and preference of vertical positions during active delivery, were higher in the first-year midwifery students compared to other students. Conclusion: It is recommended that create in-service training programs are created for the student midwives to access up-to-date information after graduation, to provide the integration of the theoretical information given to the students to the clinical environment, and to carry out visual and cohort studies on the subject. In line with the findings obtained from the study, additions can be made to the midwifery education curriculum.
Beslenme ve sağlıkla ilgili davranışların makro besin öğesi alımı üzerine etkisi
Authors: Meşe Yavuz Cansev , Başyiğit Nihal
Published: December 2022

Amaç: Bu araştırma, günlük alınan enerji ve besin öğesi miktarını belirlemek ve beslenme ve sağlıkla ilgili davranışların günlük enerji, protein, yağ ve karbonhidrat tüketimi üzerine etkisini ortaya koymak amacıyla yapılmıştır. Yöntem: Anadolu’da bir üniversitede öğrenim gören 19-25 yaş arası 729 gencin katılımı ile yapılan araştırmada, bireylerin günlük enerji ve besin öğesi tüketim miktarları belirlenmiş ve Türkiye Beslenme Rehberi’ne göre değerlendirilerek karşılanma durumu saptanmıştır. Ayrıca bireylere öğün atlama, uyumadan önce yemek yeme, sigara ve alkol kullanımı gibi beslenme ve sağlıkla ilgili sorular sorularak, bu faktörlerin makro besin öğesi alımı üzerindeki etkisi ortaya konulmuştur. Bulgular: Makro besin öğelerinin alım miktarları erkeklerde kadınlara oranla daha fazladır ve cinsiyetler arasında anlamlı derecede farklılık göstermektedir. Araştırmada, her iki cinsiyette de karbonhidrat ve sodyum alımı önerilenin üzerinde bulunurken, K vitamini, D vitamini ve potasyum ise önerilenin yarısından azını karşılamaktadır. Enerji, yağ ve protein alımı sigara içen ve içmeyenlerde istatistiksel olarak anlamlı derecede farklı bulunmuştur. Sonuç: Enerji ve makro besin öğelerinin günlük tüketimlerini öğün atlama, ara öğün tüketimi ve uyumadan önce yemek yeme durumu etkilemektedir. Diyet alımı üzerine etkili faktörleri belirlemek bireylerin diyet kalitesinin artırılmasına katkı sağlayabilir.
WORKING IN WAR: THE MAIN CHANGES IN LABOUR RELATIONS AND WORKING CONDITIONS UNDER MARTIAL LAW IN UKRAINE
Authors: Yaroshenko Oleh , Lutsenko Olena
Published: December 2022

Background: Maintaining labour regulations and the quality of working conditions is a considerable challenge during wartime and martial law. This paper outlines the changes that have affected the working life of employees who continued in employment, both inside and outside Ukraine, under martial law in 2022. Using a qualitative analysis of Ukrainian labour regulations, ILO and Ukrainian government statistics, and direct observation, we show how the legal regulation of labour relations and working conditions has changed under the influence of active hostilities. During the war in Ukraine, many employees started to work remotely, and some companies have relocated their production facilities to areas where there are no active hostilities and continue to operate. At the same time, the legal regulation and nature of labour relations and the quality of working conditions have changed significantly - yet regulations have failed to keep up with the levels of flexibility and timeliness required to respond effectively in the ongoing crisis.
Methods: In order to achieve objective scientific results, the authors used such methods as analysis and synthesis to understand and build a logical chain of ideas. The authors used the statistical method to emphasise their positions with real data regarding the situation that developed in practice.
Results and Conclusions: We draw conclusions regarding the problems of employees implementing their labour rights during wartime, identify applied aspects of labour law in wartime conditions, and propose ways to improve the situation regarding the implementation of labour rights.
Pemanfaatan Data Satelit Terhadap Prediksi Curah Hujan
Authors: Fadli Dicky Muhamad
Published: December 2022

Dengan diperkenalkan skenario emisi baru yaitu Representative Concentration Pathways (RCP) yang digunakan untuk model iklim terbaru sehingga dapat memodelkan iklim dimasa depan. Prediksi iklim dapat dimanfaatkan untuk prediksi curah hujan yang dapat dipergunakan untuk berbagai analisis hidrologi. Data RCP yang digunakan merupakan RCP 85 yang dikalibrasi dengan curah hujan setempat. Dari hasil kalibrasi didapatkan parameter statistik yang mendekati dengan stasiun hujan tersebut. Dengan menggunakan distribusi gamma, jumlah hari dan besaran hujan dapat dilakukan. Dari hasil analisis didapatkan prediksi pada tahun 2029 akan terjadi curah hujan 2126 mm/tahun dengan 121 hari hujan dengan konfigurasi 6 bulan klasifikasi basah, 2 bulan klasifikasi normal dan 4 bulan klasifikasi kering.
Getting published in international journals: Perception of Indonesian scholars in linguistics and language education on the issues they face
Authors: Adnan Zifirdaus , Purwo Bambang Kaswanti
Published: December 2022

Publishing research articles (RAs) in international journals (IJs) has been considered increasingly crucial by developing countries including Indonesia. For the Indonesian Government, publishing RAs in international journals is important to increase its competitive power academically as Indonesian universities are entering a global competition to attract students. Therefore, publishing RAs in international journals is becoming more and more important, e.g. for promotion, especially at senior levels. This study reports on the second and most widespread national-level survey of a three-year project funded by the former Indonesian Government through its Ministry of Research and Higher Education (MRHE). The central question is, "What are the key factors contributing to their lack of international research publications making the number low compared to smaller nations such as Thailand (before 2017)".This article reports the results of the second survey, with a much bigger population sample from many more universities located in many more different regions covering all the major islands in Indonesia compared to the first survey reported in our previous article. The bigger size of data is important based on the premise that the broader and the more diverse the information sources, the more comprehensive the information will be and the better understanding we gain. Some of the findings support the past results, but some contradict them.
Tüketim Kültürü Bağlamında Haftasonu Eklerinde Sunulan Yaşam Tarzları
Authors: BAŞ Miyase Nur
Published: December 2022

Doğduğumuz andan itibaren yaşamımızı devam ettirebilmek için çeşitli gereksinimlerimizi karşılamak amacıyla tüketim kavramını içselleştirmeye başlarız. Geçmişten günümüze kadar toplumların yaşadığı dönüşümlerle birlikte tüketim gereksinimlerimizde de birtakım değişim ve dönüşümler meydana gelmektedir. Yaşadığımız çağda ise, tüketim bir gereksinimin çok daha ötesinde haz almak, kimliğini ortaya koymak gibi eylemlerle özdeş hale gelmeye başlamıştır. Özellikle 1980li yıllardan itibaren Türkiye’de de hızla yaşanan ekonomik, kültürel ve sosyal gelişmeler karşısında medya, batılı ekonomik sistemin kendini yeniden üretmesi için kitlesel tüketime yönelik çeşitli yaşam tarzlarını sunmayı bir amaç haline getirmiştir. Zamanla toplumda herkesin tam bir katılıma dahil edildiği tüketim çemberi varlığını yazılı basın olarak hafta sonu eklerinde sunulan metin içerikleriyle de teşvik etmektedir.
Bu bağlamda araştırmanın amacı, tüketimin zirve yaptığı günümüzde yazılı basın tarafından inşa edilen yaşam tarzı sunumları hakkında fikir sahibi olmaktır. Dolayısıyla bir yaşam tarzı sunumu olarak tirajı en yüksek Hürriyet, Milliyet ve Sabah gazetelerinin 5 Mart 2022 - 13 Mart 2022 tarihleri arasındaki süreci kapsayan, Cumartesi-Pazar eklerindeki yazılı metinlerin içerik çözümlemesi, araştırmanın odağını oluşturmaktadır. Araştırmada, 30 farklı hafta sonu eki ve bu eklerde yer alan 622 yazılı metin analiz edilerek bulgular yorumlanmıştır. Hafta sonu eklerindeki metin içeriklerinin kitlesel, bütünleştirici ve her şeyin herkese hitap ettiği postmodernist bir tüketim kültürünü inşa ettiği sonucuna ulaşılmıştır.
Rancangan Press Tool Pembuat Komponen Penumpu Dongkrak Pantograf
Authors: Maiman Revaldy , Pratama Syael Ravi , Mulyadi Mulyadi , Budiman Daddy , Yetri Yuli
Published: December 2022

Press Tool dirancang mampu untuk membuat produk massal dan seragam dalam waktu yang relatif singkat. Salah satu produk yang dapat diproduksi menggunakan press tool ialah komponen penumpu dari dongkrak pantograf. Dongkrak pantograf digunakan dalam dunia otomotif. Kebutuhan akan produk ini meningkat seiring dengan meningkatnya kebutuhan kendaraan bermotor, khususnya mobil. Tahapan produksi komponen penumpu menggunakan press tool, antara lain: trim stop, pierching, notching, bending, cropping dan deep drawing. Metode perancangan press tool antara lain: menentukan desain dan dimensi penumpu, perhitungan, simulasi, dan analisis menggunakan solidworks simulation analysis. Tebal pelat yang aman digunakan untuk pembuatan penumpu adalah 3 mm dengan bahan ST 37. Perencanaan dimensi press tool yaitu (320 x 250 x 217) mm. Komponen press tool antara lain: shank, punch, dies, plat atas, plat bawah, plat tekan, pemegang punch, stripper plate, guide pillar, guide bush, baut, dan pena pengarah. Bahan yang digunakan untuk membuat komponen press tool antara lain: ST 37, ST 42, kuningan, standar HASCO, standar AISI, dan standar Polman Bandung. Gaya total yang terjadi pada pembuatan penumpu adalah 442798,2 N.
Rancang Bangun Welding Fixture Table Untuk Pemotongan Dan Pegelasan Plat
Authors: Yetri Yuli , Ganumba Oktavianus , Zamrud Kurnia Ahmad Amdi , Budiman Daddy , Junaidi Junaidi
Published: December 2022

Pengelasan (Welding) adalah sebuah kegiatan menyambungkan logam dengan melalui fase cair logam tersebut sebelum akhirnya membeku dan tercipta sambungan. Teknik Pengelasan semakin banyak dipergunakan secara luas dalam konstruksi bangunan dan konstruksi mesin. Selain untuk menyambungkan logam, pengelasan juga memiliki fungsi sebagai media pemotongan (Cutting). Pegelasan dan pemotongan adalah suatu pekerjaan yang memerlukan keakuratan. Pekerjaan pengelasan tanpa alat bantu akan menjadikan hasil tidak akurat, sehingga membutuhkan welder yang ahli untuk mendapatkan hasil yang diinginkan tersebut. Tujuan dari penelitian ini adalah membuat alat bantu pemotongan plat yang dinamakan Welding Fixture Table. Alat ini digunakan untuk membantu memegang benda kerja berbentuk plat agar mudah dilakukan proses pemotongan. Alat ini memiliki kemampuan pencekam plat maksimum dengan tebal 6 mm sebesar 750 mm x 610 mm dengan berat 21,6 Kg serta dapat diatur untuk ukuran yang lebih kecil, dilengkapi dengan sistem pergeseran sliding di bagian meja atas untuk mengatur ukuran pencekaman benda kerja, serta sistem rotasi yang akan memudahkan operator memilih posisi pengelasan atau pemotongan yang diinginkan.
Sistem Predictive Maintenance Bearing Pada Mesin Super Mixer Granula Dengan Menggunakan Sensor Acceelerometer MPU-6050
Authors: Ardhian Nugroho Oktavianus , Angel Tandiawan Catherine
Published: December 2022

PT Hexpharm Jaya Laboratories adalah salah satu perusahaan yang merupakan bagian dari Kalbe Company yang bergerak secara khusus dalam bidang pengembangan, produksi, pengolahan, dan pemasaran obat. Proses pengolahan bahan baku obat di PT Hexpharm Jaya Laboratories menggunakan beberapa mesin, salah satunya adalah mesin SMG (Super Mixer Granula). Mesini ini digunakan untuk mencampur bahan baku obat dan merupakan proses pengolahan awal sebelum menjadi granul. Masalah yang sering timbul pada mesin ini yaitu masalah penggantian bearing. Bearing yang terpasang di bagian shaft penghubung gearbox dengan granula sering mengalami kerusakan yang menyebabkan produksi berhenti / breakdown.  Proses unplanned maintenance ini sebelumnya sudah coba diatasi dengan penghitungan umur bearing dan alignment shaft penghubung untuk menggurangi getaran, tetapi bearing tetap mengalami kerusakan sebelum waktunya. Dalam tulisan ini dibuatlah suatu sistem untuk memprediksi kapan bearing perlu diganti dengan mencatat data getaran yang terjadi. Tujuan dari penelitian ini adalah mendapatkan sistem yang mencegah terjadinya unplanned maintenance sehingga tidak mengganggu proses produksi. Dengan menggunakan sensor MPU-6050 getaran pada bearing diukur dan direkam. Hasilnya didapat suatu sistem predictive maintenance yang dapat mencegah terjadinya breakdown yang mengakibatkan berhentinya proses produksi. Sistem ini dibuat dengan merekam getaran yang terjadi ketika mesin bekerja dan digunakan sebagai cara untuk memprediksi lifetime bearing.  Sistem ini berhasil mengukur nilai getaran bearing dan dapat ditampilkan sehingga membantu teknisi maintenance memperkirakan waktu yang tepat untuk penggantian bearing di mesin SMG.
Embedded Fibre Reinforced Polymers (FRP) in Concrete Structures According to the New Version of Eurocode 2
Authors: Oller Ibars Eva , Torres Lluís , De Diego Ana
Published: December 2022

The new version of Eurocode 2 will include for the first time an informative annex, Annex R “Embedded FRP reinforcement”, to design reinforced concrete structures with fibre reinforced polymer (FRP) reinforcement. FRP embedded reinforcement has some advantages such as their low susceptibility to corrosion, high‐strength, and low life‐cycle cost. FRP rebars can be used as longitudinal or transverse reinforcement in a similar way than conventional steel rebars, but considering some particular aspects, such as their linear elastic behaviour up to failure or their lower modulus of elasticity, which may condition the design by the verification of theserviceability limit state. Since, the content of Annex R is new, a summary and background related to all aspects required for designing with FRP reinforcement are given in this paper.
Strengthening Existing Concrete Structures with Fibre Reinforced Polymers (FRP) in the New Version of Eurocode 2
Authors: Oller Eva , De Diego Ana , Torres Lluís , Madera Pedo
Published: December 2022

This paper aims to introduce the content of Annex J “Strengthening of Existing Concrete Structures with CFRP” of Eurocode 2 [1]. This is first time that the design of adhesively bonded reinforcement with CFRP has been introduced in the European regulations through an informative annex. Annex J considers two different bonded strengthening techniques: externally bonded reinforcement (EBR) that consists of bonding CFRP strips or sheets to the surface of concrete elements, and near surface mounted reinforcement (NSM) that consists of embedding a CFRP strip or rod to a slot cut in the concrete cover. Since, the content of Annex J is new, asummary and background related to all aspects required for designing CFRP strengthened systems for concrete structures, are given in this paper.
Comprehensive Assessment and Pharmacotherapy of Patients with Chronic Pain Syndrome Due to Diabetic Neuropathy and Postherpetic Neuralgia
Authors: Rygiel Katarzyna
Published: December 2022

Management of chronic pain, usually associated with comorbid conditions, remains challenging. General practitioners, together with multidisciplinary teams of specialists, play an important role in diagnosing and treating patients with chronic pain of different origin. This article outlines the main mechanisms underlying chronic nociceptive and neuropathic pain and describes some helpful techniques to initially evaluate and regularly monitor pain. Pharmacologic treatment options, including their benefits and adverse effects, with particular emphasis on the management of diabetic neuropathy and postherpetic neuralgia, commonly seen in the primary care practice setting, are presented.

Chronic pain, regardless of its cause, is a disease syndrome and, as such, requires a comprehensive, individualised approach to each patient reaching beyond symptom control. Collaboration of physicians (general practitioners, diabetologists, neurologists, and pain specialists), pharmacists, and nurses in the management of patients with diabetic neuropathy and postherpetic neuralgia improves patient safety and contributes to better adherence to therapeutic regimens, which leads to more favourable outcomes and improved quality of life.
BCG-Unresponsive Bladder Cancer: New Frontiers in the Treatment Landscape
Authors: Shenoy Satyendra
Published: December 2022

This Ferring-organised Meet-The-Expert symposium at the European Society of Medical Oncology (ESMO) 2019 meeting aimed to discuss new treatment modalities in the management of high-risk, non-muscle invasive bladder cancer (NMIBC). The chairperson Prof Palou commenced the session by discussing the need for newer interventions to address the failure of bacillus Calmette–Guérin (BCG), the first-line treatment against NMIBC, in a substantial proportion of patients. Prof Palou emphasised the need to clearly define refractory disease to optimise second-line treatments, before introducing immune checkpoint inhibitors as a promising class of drug for the treatment of BCG-unresponsive NMIBC. Prof Shariat discussed a case study to define key clinical timepoints for evaluating therapeutic outcomes of BCG treatment. He further outlined factors to be considered before deciding on radical cystectomy in BCG-unresponsive NMIBC. Prof Babjuk listed some of the landmark trials conducted recently to investigate chemotherapeutic agents such as mitomycin C (MMC) and docetaxel in BCG-unresponsive patients before highlighting the role of advanced drug delivery technologies such as electromotive drug administration (EMDA), hyperthermic intravesical chemotherapy, and radiofrequency-induced thermo-chemotherapy effect (RITE) in improving the effectiveness of these agents. Prof Powles shared data from some of the trials investigating immune checkpoint inhibitors such as PURE-01, ABACUS, KEYNOTE, to underscore the importance of biomarkers in selecting appropriate treatment strategies for NMIBC.
Analisis Metode Failure Mode and Effect Analysis (FMEA) dan Fault Tree Analysis (FTA) Untuk Identifikasi Penurunan Kualitas Produk Toyota Hi-Ace (Studi Kasus di PT. EDS Manufacturing Indonesia)
Authors: Lestari Sri , Septiyana Diah , Yuniawati Winda
Published: December 2022

Tingkat kegagalan (defect) tinggi merupakan suatu permasalahan yang selalu diupayakan untuk diminimasi oleh suatu perusahaan guna meningkatkan kualitas dari produk yang dihasilkan, begitu juga yang dilakukan oleh PT. EDS Manufacturing Indonesia (PEMI). PT. EDS Manufacturing Indonesia (PEMI) merupakan perusahaan manufaktur carline Toyota HI-ACE untuk kendaraan bermotor. Oleh karena kegagalan yang tinggi pada produk bisa merugikan perusahaan, maka dilakukan penelitian ini dengan menggunakan 2 metode yaitu metode Failure Mode and Effect Analysis (FMEA) dan Fault Tree Analysis (FTA). Penelitian dengan metode Failure Mode and Effect Analysis (FMEA) pada PT. EDS Manufacturing Indonesia di carline Toyota HI-ACE menunjukkan adanya berbagai moda kegagalan pada area produksi dan quality assurance. Metode FMEA dilakukan dengan memprioritaskan RPN dari 2 moda kegagalan yang menjadi prioritas berdasarkan RPN tertinggi yaitu wrong dimension dan demage insulation. Tahapan berikutnya adalah menganalisa resiko yang berperan terhadap kegagalan  dengan menggunakan Fault Tree Analysis (FTA). Berdasarkan data analisis dengan metode FMEA diperoleh nilai RPN tertinggi terdapat pada mode kegagalan demage insulation dengan nilai RPN sebesar 324 atau sebesar 14.78% dan mode kegagalan wrong dimension dengan nilai RPN sebesar 280 atau sebesar 12.77%.

 

Kata kunci: mode kegagalan, analisa resiko, FMEA, FTA, nilai RPN
Embryological Aspects of Creating a New Humanized Transgenic Mouse Line with an Integrated Human Gene HLA A*02:01:01:01
Authors: Savchenko E. S. , Ogneva N. S. , Karkischenko N. N.
Published: December 2022

The accumulation of scientific data in the field of pharmacogenetics requires the creation of adequate biomodels to reflect the immunogenetic characteristics of different population groups. We have obtained the ancestors of a new humanized transgenic mouse line carrying the human HLA-A*02:01:01:01 gene, which is characteristic of the Russian population. The new biomodels was created using the pronuclei microinjection method of a linearized fragment of genetically engineered DNA construct into zygotes, followed by overnight cultivation in CO2 incubator and transfer of potentially modified embryos at the stage of two 4.0 blastomere to pseudopregnant foster females. A total of 91 living offspring were obtained and analyzed, with 18 pups carrying the target genome modification. The resulting transgenic animals were used to create a new line of mouse biomodels carrying the human HLA-A*02:01:01:01 gene.
Active Substances Isolated from the Secretion of Siberian Musk Deer in a Liposomal Dosage Form
Authors: Gasanov M. T. , Fokin Yu. V. , Lyublinskiy S. L. , Alimkina O. V. , Taboyakova L. A. , Karkischenko V. N.
Published: December 2022

Liposomal forms of preparations containing biologically active substances extracted from renewable sources of raw materials of plant and animal origin are attracting considerable research and practical interest. Liposomal drugs are efficiently absorbed in the gastrointestinal tract, retaining their structure while passing through the liver and entering the target cell. This allows either smaller amounts of the active substance to be used without losing bioavailability or its effective concentration to be increased.

Deer musk liposomes administered at doses equivalent to 300, 1500 and 3000 mg/person/day were found to exhibit an actoprotective effect, whose intensity at the minimum dose (300 mg) is comparable to that achieved at the maximum dose (3000 mg).

A course daily transpalatal administration of musk deer liposomes for 14 days was established to statistically significantly improve the indices of physical endurance and working capacity of rats in forced swimming tests under load, kineso-hydrodynamic models of swimming and rotarod performance tests. The observed increase in indicators persisted for another seven days after the cessation of administration, which indicates pharmacological cumulation. The tested drug reduces locomotor and orienting-exploratory activity, at the same time as exhibiting no adverse effect on the psycho-emotional and intoxication status of animals. In addition, no local irritant action on the route of administration was noted. The drug is assigned to toxicity class VI (relatively harmless).
Hiperwarburgismo: la “hipoglucemia feliz” de los pacientes oncológicos
Authors: Roosemberg Ordóñez Fernando José , Veliz Ortega José , Ortega Uscocovich Valeria , Bowen Flores Aquiles , Garcia Cruz Carlos
Published: December 2022

Introducción: La glucosa es el combustible energético cerebral, esta relación es establecida de manera integral en la inmensa mayoría de revisiones, debido al ávido consumo -y casi exclusivo - glucósico por parte del tejido neuronal. En esta esfera, la hipoglucemia se traduce por defecto en un conjunto de síntomas neurológicos, resultado del estado neuroglucopénico. Cuando la caída de estos niveles glicémicos es pronunciada desencadena alteraciones del estado sensorial, pudiendo llegar al coma con daños irreversibles de sostenerse en el tiempo.
Propósito de la revisión: El objetivo de la revisión es presentar un caso de hipoglucemia severa sin sintomatología neuroglucopénica.
Recientes hallazgos: Al ausencia de sintomatología neurológica se da debido al consumo del lactato – tradicionalmente producto anaerobiótico – como una vía metabólica energética alternativa al consumo de glucosa. La hipoglucemia puede ser compensada a nivel neurológico con sistemas lanzadores de lactato en el tejido neuronal, este puede sustituir a la glucosa como sustrato energético del cerebro.
Conclusiones: La hipoglicemia sin síntomas adrenérgicos o neuroglucopénicos es un tema vinculado a pacientes oncológicos, y propone al lactato como combustible del tejido nervioso adicional a la glucosa. Por otra parte, la asociación lactato = hipoperfusión, es otra entidad que debe ser revisada y reanalizada por todo lo que implica el lactato dentro de la vía fisiopatológica metabólica corporal.
Fungsi Badan Kepegawaian dan Pengembangan SDM dalam Melakukan Mediasi pada Proses Perceraian PNS di Lingkungan Pemerintah Kabupaten Tana Tidung
Authors: Somibeda Lamadokend Juliana , Sabil Ibnu , Sastrawan Putra Anak Agung Made
Published: December 2022

Marriage according to Law Number 1 of 1974 is an inner and outer bond between a man and a woman as husband and wife to live a perfect, happy, and eternal life. Not all marriages can run as expected because there is no agreement or conflicting behavior that results in divorce in both the general public and civil servants. This study aims to describe and analyze staffing policies in fostering household harmony and support improving employee performance, analyze the factors causing civil servant divorce, analyze the mediation process carried out by BKPSDM as a form of regional organizational function in the civil servant divorce process and analyze obstacles and solutions. In mediating the divorce process for civil servants within the Tana Tidung Regency Goverment. This study uses a qualitative descriptive method with data collection techniques through interviews, observation and documentation. This study concludes that the government policy of Tana Tidung Regency in fostering household harmony is carried out through religious activities, giving leave, counseling guidance, and socialization about household harmony. Factors causing civil servant divorce include infidelity, economy, one party being a drug addict, and differences in principles, ideology, and religion. BKPSDM as a mediator uses the 5 mediation principles of David Spencer and Michael Brogan in the civil servant divorce apllication process. The obstacles faced werw that one of the parties was unable to attend, and parties were uncooperative, unable to accept suggestions, and incomplete administrative requirements. The solution is to make a summons to the parties concerned, bring other parties to obtain additional information, and contact employees to complete the requirements for submitting a divorce permit so that the next process can be carried out.
HUBUNGAN ANTARA KLASIFIKASI STROKE DENGAN GANGGUAN FUNGSI KOGNITIF PADA PASIEN STROKE
Authors: Nopia Dewi , Huzaifah Zaqyyah
Published: December 2022

Stroke is the second leading cause of death in the world. Stroke is a vascular disorder caused by blockage or rupture of blood vessels in the brain, as a result of these conditions arises a clinical disorder resulting from damage to brain cells in certain parts. Symptoms can disrupt the process of mental activity or sublime cortical function including cognitive function. This study aims to determine the relationship between stroke classification with cognitive impairment in stroke patients. This type of research used in this study is a correlation analysis, with a cross-sectional design, a sample of 36 respondents according to criteria, using Chi-Square at α = 0.05. There is a relationship between the classification of stroke with cognitive impairment in stroke patients with a value of ρ value = 0,000.

Penyakit stroke merupakan penyebab kedua kematian di dunia. Stroke merupakan gangguan vaskular yang disebabkan oleh sumbatan atau pecahnya pembuluh darah diotak, akibat dari keadaan tersebut timbul suatu kelainan klinis akibat dari kerusakan sel otak pada bagian tertentu. Gejala dapat terganggunya proses aktifitas mental atau fungsi kortilal luhur termasuk fungsi kognitif. Penelitian ini bertujuan mengetahui hubungan antara klasifikasi stroke dengan gangguan fungsi kognitif pada pasien stroke. Jenis penelitian yang digunakan dalam penelitian ini adalah analisa korelasi, dengan rancangan cross-sectional, sampel 36 responden sesuai dengan kriteria, menggunakan Chi Square pada α = 0,05. Ada hubungan antara klasifikasi stroke dengan gangguan fungsi kognitif pada pasien stroke dengan nilai ρ value = 0,000.
HIGH-FIDELITY SIMULATION DAN DEBRIEFING SEBAGAI MODEL PENINGKATAN INTERPROFESSIONAL COLLABORATION DALAM PENDIDIKAN KEPERAWATAN
Authors: Wibowo Hery
Published: December 2022

Latar Belakang: Beberapa tahun terakhir traning high-fidelity simulation yang memakai simulasi pasien telah mengambil peranan besar dalam pendidikan keperawatan, dilihat dari segi interprofesi yang melibatkan kolaborasi perawat dan dokter. Tujuan: Mengetahui keefektifan penggunaan teknik debriefing dengan high-fidelity simulation untuk meningkatkan kompetensi interprofessional collaboration dalam pendidikan keperawatan. Metode: Literature review dari berbagai database jurnal online ProQuest, EBSCOhost, kemudian dikelompokkan sesuai dengan temanya dan dianalisis kelebihan serta kekurangan high-fidelity simulation Hasil: Ditemukan kebanyakan penelitian memiliki kekurangan dan kekakuan dalam high-fidelity simulation. Namun, dapat menjadi lebih efektif jika dikolaborasikan dengan metode Debriefing.
EFEKTIVITAS PENDIDIKAN KESEHATAN PADA PASIEN HIPERTENSI STUDI NARRATIVE REVIEW
Authors: Manto Onieqie Ayu Dhea , Islamiaty Intan Nur
Published: December 2022

Latar Belakang: Penyakit hipertensi merupakan masalah kesehatan serius pada masyarakat. Penyakit hipertensi setiap tahunnya mengalami peningkatan. Data Riskesdas pada tahun 2018 mencapai prevalensi (34,1%) di Indonesia dan prevalensi (44,1%) di Kalimantan Selatan. Salah satu faktor yang menyebabkan terjadinya hipertensi adalah pola hidup. Kurangnya pengetahuan masyarakat mengenai pola hidup yang sehat memicu terjadinya kelalaian pengendalian tekanan darah. Hal tersebut berpotensi menyebabkan terjadinya komplikasi pada pasien hipertensi. Upaya yang dapat dilakukan untuk mencegah dan mengendalikan penyakit hipertensi adalah memberikan pendidikan kesehatan kepada pasien hipertensi untuk menjaga dan memperbaiki pola hidup sehat. Tujuan: Menganalisis Efektivitas Pendidikan Kesehatan pada pasien hipertensi. Metode: Rancangan Penelitian Narrative Review. Kriteria jurnal yang digunakan disaring berdasarkan judul literatur, abstrak dan kata kunci atau Keyword yaitu Pendidikan Kesehatan+pasien hipertensi. Hasil: Sebagian besar pasien hipertensi yang telah diberikan pendidikan kesehatan mengalami perubahan dari segi perilaku individu dan tekanan darah. Hasil analisis yang didapat adalah sebagian besar penelitian menunjukkan adanya efektivitas pendidikan kesehatan pada pasien hipertensi. Kesimpulan: Pemberian Pendidikan Kesehatan pada pasien hipertensi dapat mengendalikan tekanan darah. Bagi instansi terkait meliputi dinas kesehatan, rumah sakit, puskesmas maupun fasilitas kesehatan diharapkan dapat meningkatkan pengetahuan pasien hipertensi terkait pengendalian tekanan darah misalnya mengurangi konsumsi garam, meminum obat antihipertensi, dan selalu melakukan pemeriksaan tekanan darah ke puskesmas atau tenaga kesehatan lainnya. Hal tersebut dapat membantu pasien dalam mengendalikan tekanan darahnya.
GAMBARAN RESPONSE TIME PASIEN DI IGD RSI SITI AISYAH MADIUN
Authors: Sukamto Filia Icha
Published: December 2022

Latar Belakang : Respon Time merupakan kecepatan dalam penanganan pasien, dihitung sejak pasien datang sampai dilakukan penanganan, waktu tanggap yang baik bagi pasien yaitu ≤ 5 menit. Semakin cepat pasien mendapat pertolongan definitif maka kemungkinan kesembuhan dan keberlangsungan hidup seseorang akan semakin besar, sebaliknya kegagalan response time di IGD dapat berakibat fatal berupa kematian atau cacat permanen. Tujuan :  penelituian ini adalah untuk mengetahui gambaran response time pasien di IGD RSI Siti Aisyah Madiun. Metode : Jenis penelitian ini adalah diskriptif, dengan populasi pasien di IGD RSI Siti Aisyah Madiun. Sampel penelitian adalah sebagian pasien di IGD, teknik pengambilan sampling quota sampling dengan jumlah sampel 92 responden. Teknik pengambilan data dengan lembar observasi untuk response time dan kategori kegawatan pasien. Analisis data univariat dengan prosentase. Hasil : Hasil penelitian dari 92 responden didapatkan 72 (78,3%) responden ditangani dengan respon time cepat (< 5 menit) dan 20 (21,7%) responden ditangani dengan respon time lambat (> 5 menit). Kesimpulan : Berdasarkan hasil penelitian ini, maka disarankan agar petugas IGD senantiasa lebih sigap/tanggap dalam penanganan pasien gawat darurat agar tercapainya salah satu indikator mutu pelayanan di IGD yaitu respon time yang < 5 menit.
Gambaran Pengetahuan Perawat Tentang Metode ESI (Emergency Severity Index) DI Ruang Instalasi Gawat Darurat RSUD X
Authors: Muthmainnah Muthmainnah muthmainnah
Published: December 2022

Latar Belakang: Masalah yang sering dijumpai Di rumah sakit adalah banyak pasien yang diberikan tindakan tidak sesuai dengan kriteria kegawatan dan kebijaksanaan prioritas yang wajib ditangani sang perawat, sebagai akibatnya bisa menyebabkan kepadatan. Sedangkan pelayanan IGD membutuhkan layanan yg cepat dan sempurna. salah satunya merupakan triase (Emergency Severity Index) ESI yang waktu ini diterapkan di Amerika menggunakan keunggulan identifikasi pasien lebih cepat, tepat serta tanpa perlu menunggu dokter triase. Tujuan: Penelitian ini bertujuan untuk mengidentifikasi gambaran tingkat pengetahuan perawat tentang metode ESI. Metode: Metode Penelitian ini menggunakan menggunakan Deskriptif dengan teknik Total Sampling. Sampel penelitian adalah 35 perawat yang bekerja di IGD RSUD X dan pengumpulan data dilakukan dengan lembar kuesioner. Hasil: Hasil yang didapatkan mayoritas perawat IGD didapatkan memiliki tingkat pengetahuan baik. sebagian besar perawat IGD RSUD X berusia 27-37 tahun dengan tingkat pengetahuan baik, perawat berpendidikan tinggi S1 dan D3 Keperawatan, sebagian besar jenis kelamin perawat ialah laki-laki, sebagian besar lama kerja yang dilakukan perawat ialah cepat (7 Jam) dan pengetahuan baik  yang mengikuti pelatihan. Kesimpulan: Kesimpulan dari penilitian ini jika tingkat pengetahuan perawat baik tentang triage. Saran kepada perawat, yang masih belum memahami ESI, untuk mengikuti pelatihan dan lebih memahami bagaimana pengaplikasiannya.
КУЛЬТУРА ТРАДИЦИОННОГО ПИТАНИЯ НА РУССКОМ СЕВЕРЕ:
ПРОДУКТЫ С ПОЛЯ И ОГОРОДА
Authors: Воронина Татьяна Андреевна
Published: December 2022

В статье рассматривается сугубо этнографическая, важная для любого народа тема традиционного питания. Русский Север – особый регион, имеющий свое лицо, культурное, социальное, церковное, но вместе с тем это часть общерусского пространства. Поэтому так важно выделить в традиции севернорусского питания уникальное, региональное, связанное с природными и культурными особенностями этого края. Автор опирается на обширный круг неопубликованных источников – полевых, архивных, а также на научную литературу, на основе которых и выстраивается картина традиционного питания северян.
The article deals with a purely ethnographic, important for any nation topic of traditional nutrition. The Russian North is a special region that has its own face, cultural, social, ecclesiastical, but at the same time it is part of the all-Russian space. That is why it is so important to single out in the tradition of northern Russian nutrition the unique, regional, associated with the natural and cultural characteristics of this region. The author relies on a wide range of unpublished sources - field, archival, as well as scientific literature, on the basis of which the picture of the traditional diet of northerners is built.
Genetic evidence of aberrant striatal synaptic maturation and secretory pathway alteration in a dystonia mouse model
Authors: Yellajoshyula Dhananjay , Opeyemi Sunday , Dauer William T. , Pappas Samuel S.
Published: December 2022

Animal models of DYT-TOR1A dystonia consistently demonstrate abnormalities of striatal cholinergic function, but the molecular pathways underlying this pathophysiology are unclear. To probe these molecular pathways in a genetic model of DYT-TOR1A, we performed laser microdissection in juvenile mice to isolate striatal cholinergic interneurons and non-cholinergic striatal tissue largely comprising spiny projection neurons during maturation. Both cholinergic and GABAergic enriched samples demonstrated a defined set of gene expression changes consistent with a role of torsinA in the secretory pathway. GABAergic enriched striatum samples also showed alteration to genes regulating synaptic transmission and an upregulation of activity dependent immediate early genes. Reconstruction of Golgi-Cox stained striatal spiny projection neurons from adult mice demonstrated significantly increased spiny density, suggesting that torsinA null striatal neurons have increased excitability during striatal maturation and long lasting increases in afferent input. These findings are consistent with a developmental role for torsinA in the secretory pathway and link torsinA loss of function with functional and structural changes of striatal cholinergic and GABAergic neurons. These transcriptomic datasets are freely available as a resource for future studies of torsinA loss of function-mediated striatal dysfunction.
Continuous real-time cow identification by reading ear tags from live-stream video
Authors: Bastiaansen John W.M. , Hulsegge Ina , Schokker Dirkjan , Ellen Esther D. , Klandermans Bert , Taghavi Marjaneh , Kamphuis Claudia
Published: December 2022

In precision dairy farming there is a need for continuous and real-time availability of data on cows and systems. Data collection using sensors is becoming more common and it can be difficult to connect sensor measurements to the identification of the individual cow that was measured. Cows can be identified by RFID tags, but ear tags with identification numbers are more widely used. Here we describe a system that makes the ear tag identification of the cow continuously available from a live-stream video so that this information can be added to other data streams that are collected in real-time. An ear tag reading model was implemented by retraining and existing model, and tested for accuracy of reading the digits on cows ear tag images obtained from two dairy farms. The ear tag reading model was then combined with a video set up in a milking robot on a dairy farm, where the identification by the milking robot was considered ground-truth. The system is reporting ear tag numbers obtained from live-stream video in real-time. Retraining a model using a small set of 750 images of ear tags increased the digit level accuracy to 87% in the test set. This compares to 80% accuracy obtained with the starting model trained on images of house numbers only. The ear tag numbers reported by real-time analysis of live-stream video identified the right cow 93% of the time. Precision and sensitivity were lower, with 65% and 41%, respectively, meaning that 41% of all cow visits to the milking robot were detected with the correct cow’s ear tag number. Further improvement in sensitivity needs to be investigated but when ear tag numbers are reported they are correct 93% of the time which is a promising starting point for future system improvements.
NyctiDB: A non-relational bioprocesses modeling database supported by an ontology
Authors: Caño De Las Heras Simoneta , Gargalo Carina L. , Caccavale Fiammetta , Gernaey Krist V. , Krühne Ulrich
Published: December 2022

Strategies to exploit and enable the digitalization of industrial processes are on course to become game-changers in optimizing (bio)chemical facilities. To achieve this, these industries face an increasing need for process models and, as importantly, an efficient way to store the models and data/information. Therefore, this work proposes developing an online information storage system that can facilitate the reuse and expansion of process models and make them available to the digitalization cycle. This system is namedNyctiDB, and it is a novel non-relational database coupled with a bioprocess ontology. The ontology supports the selection and classification of bioprocess models focused information, while the database is in charge of the online storage of said information. Through a series of online collections,NyctiDBcontains essential knowledge for the design, monitoring, control, and optimization of a bioprocess based on its mathematical model. OnceNyctiDBhas been implemented, its applicability and usefulness are demonstrated through two applications. Application A shows howNyctiDBis integrated inside the software architecture of an online educational bioprocess simulator. This implies thatNyctiDBprovides the information for the visualization of different bioprocess behaviours and the modifications of the models in the software. Moreover, the information related to the parameters and conditions of each model is used to support the users’ understanding of the process. Additionally, application B illustrates thatNyctiDBcan be used as AI enabler to further the research in this field through open-source and reliable data. This can, in fact, be used as the information source for the AI frameworks when developing, for example, hybrid models or smart expert systems for bioprocesses. Henceforth, this work aims to provide a blueprint on how to collect bioprocess modeling information and connect it to facilitate and empower the Internet-of-Things paradigm and the digitalization of the biomanufacturing industries.