bluuebunny/crossref_metadata_2025 huggingface dataset:
Ciudad e hipertelia
Authors: Guillén Germán Vargas , Congote Lina Marcela Gil
Published: October 2022

Este artículo caracteriza la noción hipertelia como ampliación autónoma del télos, de las posibilidades de sentido; o, como estructura rígida que opera como base de la heteronomía, de la determinación (teleología y teleonomía). En la sección I presenta 10 Tesis sobre la relación hipertelia y ciudad como entorno de individuación que opera como dispositivo técnico. II. Aborda el alcance del título mentalidad técnica. III. Enlaza la mentalidad técnica (desde la fenomenología realista de G. Simondon, la fenomenología asubjetiva de J. Patočka) con la mentalidad democrática (fenomenología trascendental de Daniel Herrera). Por último, aborda las mutuas relaciones entre formación e individuación.
Inovasi Pelayanan Publik untuk Meningkatkan Pelayanan Kependudukan di Kota Surabaya
Authors: Wibowo Cahyo Bima Sakti
Published: October 2022

Abstract

This study aims to describe the quality of public services using the approach of Zeithaml, Berry, and Parasuraman. The City of Surabaya through the Department of Population and Civil Registration of the City of Surabaya made an electronic "6 In 1" (birth-death-moving-coming-moving-out-marriage-divorce) innovation aimed at providing easy access to public services and online application for population administration files. Method The research used is qualitative with descriptive type. Determination of informants with purposive and accidental techniques. Data collection was done by interview, observation, and documentation techniques. The data analysis technique used qualitative analysis. The conclusion of the research innovation "6 In 1" is able to significantly improve the quality of public services so that they are more efficient and effective.

Keywords: innovation, population service, local government

 

Abstrak

Penelitian ini bertujuan mendiskripsikan kualitas pelayanan publik dengan menggunakan pendekatan dari Zeithaml, Berry, dan Parasuraman. Kota Surabaya melalui Dinas Kependudukan Dan Catatan Sipil Kota Surabaya membuat inovasi “6 In 1” (kelahiran- kematian- pindah datang- pindah keluar- perkawinan-perceraian) secara elektronik  bertujuan  memberi kemudahan akses layanan publik dan permohonan berkas administrasi kependudukan secara online.. Metode penelitian yang digunakan adalah kualitatif dengan tipe deskriptif. Penetapan informan dengan teknik purposive dan accidental. Pengambilan data dilakukan dengan teknik wawancara, observasi, dan dokumentasi. Teknik analisis data menggunakan analisis kualitatif. Kesimpulan penelitian inovasi “6 In 1” mampu meningkatkan kualitas pelayanan publik secara signifikan sehingga lebih efisien dan efektif.

Kata kunci: inovasi, layanan kependudukan, pemerintah lokal
Transparansi Organisasi Perangkat Daerah dalam Penyelenggaraan Pelayanan Publik Pada Era Otonomi Daerah
Authors: Windari Irom Putri Fatimah Malahayati
Published: October 2022

Abstract The importance of transparency in local government is a concern in this study, especially the close relationship between local government and citizens. This study aims to determine the transparency of regional apparatus organizations in the implementation of public services in the era of regional autonomy with a case study at the Surabaya City Trade Office. This study uses a descriptive qualitative approach. The research locus at the Surabaya City Trade Office. The steps of collecting research data are through observation, in-depth interviews and literature study. Stages of checking the validity of the data using data triangulation. Analysis of research data using qualitative analysis of the interactive model. The conclusion of the research on the transparency of the Surabaya City Trade Office in the process of providing business license services is not yet fully open; related to the ease of regulations and service procedures not yet fully understood by the public in the process of applying for a business license; On the aspect of ease of obtaining information regarding various aspects of public service delivery, there are still people who have difficulty.AbstrakPentingnya transparansi dalam pemerintah lokal menjadi perhatian dalam penelitian ini, terutama hubungan  erat antara pemerintah daerah dan warga. Studi ini bertujuan mengetahui transparansi organisasi perangkat daerah dalam penyelenggaraan pelayanan publik pada era otonomi daerah dengan studi kasus pada Dinas Perdagangan Kota Surabaya. Penelitian ini menggunakan pendekatan kualitatif deskriptif. Lokus penelitian di Dinas Perdagangan Kota Surabaya. Langkah pengumpulan data penelitian melalui observasi, wawancara mendalam dan studi pustaka. Tahapan pemeriksaan keabsahan data menggunakaan triangulasi data. Analisis data penelitian menggunakan analisis kualitatif model interatif. Kesimpulan penelitian transparansi Dinas Perdagangan Kota Surabaya pada proses penyelenggaraan pelayanan izin usaha belum sepenuhnya terbuka; terkait kemudahan peraturan dan prosedur pelayanan belum sepenuhnya dipahami oleh masyarakat pada proses mengajukan surat izin usaha; pada aspek kemudahan untuk memperoleh informasi mengenai berbagai aspek penyelenggaraan pelayanan publik masih ada masyarakat yang kesulitan.
Predictors and risk-adjusted outcomes of new-onset postoperative atrial fibrillation in repeat surgical and valve-in-valve transcatheter aortic valve replacement
Authors: Dokko Julia
Published: October 2022

Aim: New-onset postoperative atrial fibrillation/flutter (POAF/AFL) complications have not been well studied for repeat aortic valve replacements (r-AVR); this study identified risk factors predisposing to POAF/AFL and POAF/AFL’s effect upon risk-adjusted outcomes. Methods: Using New York State’s Statewide Planning and Research Cooperative System records (2005-2018), multivariable forward selection models identified risks predictive of POAF/AFL. To identify POAF/AFL’s impact upon risk-adjusted mortality/morbidity (MM) and 30-day readmission (READMIT), forward selection logistic regression models applied Firth bias correction to address data sparsity. Results: Of the 242 r-AVR patients, 147 underwent repeat surgical aortic valve replacements (r-SAVR) and 95 underwent valve-in-valve transcatheter aortic valve replacements (ViV-TAVR); 39.46% of r-SAVR and 43.16% of ViV-TAVR patients had POAF/AFL. R-SAVR patients with POAF/AFL were older (69.7 ± 11.1 vs. 56.7 ± 13.2 years, P < 0.01) compared to R-SAVR patients without POAF/AFL. Multivariable models identified an enhanced POAF/AFL risk for elderly (OR: 1.05, 95%CI: 1.03-1.07, P < 0.01) and cerebral vascular disease (OR: 2.18, 95%CI: 1.05-4.55, P = 0.04) patients. Bivariately, POAF/AFL was associated with READMIT, but not MM. Correspondingly, multivariable models found POAF/AFL increased READMIT (OR: 3.12, 95%CI: 1.46-6.65, P < 0.01), but not MM. However, black race (OR: 4.97, 95%CI: 1.61-15.37, P < 0.01) and Elixhauser score (OR: 1.05, 95%CI: 1.02-1.08, P < 0.01) increased risk for MM. Conclusion: More common in older and cerebrovascular disease patients, 41% of r-AVR patients with POAF/AFL had increased READMIT risk; thus, future investigations should focus on improving POAF/AF r-AVR patients’ post-discharge continuity of care.
Editorial (Português)
Authors: Almeida Tiago da Silva
Published: October 2022

Este artigo representa a opinião do autor sobre o campo da arquitetura de computadores e os desafios futuros. Este trabalho tenta estabelecer como a computação se tornou tão importante como é hoje. Além disso, procura elencar alguns dos principais desafios da área de projetos de computadores. Assim, este artigo foi escrito para estudantes e pesquisadores que desejam ver o panorama geral do assunto, e nenhum destes é amplamente discutido, depois, essa tarefa é quase impossível e não é a intenção. No entanto, alguns grandes insights podem surgir deste artigo, uma vez que o futuro parece ser co-design e aproximado.
On the Quantum Nature of a Fireball Created in Ultrarelativistic Nuclear Collisions
Authors: Kizka Valeriy
Published: October 2022

In the article, the fireball formed in the collision of relativistic nuclei is considered as a quantum object. Based on this, an attempt is made to explain the difference in the measurements of hyperon yields in the two experiments - NA49 and NA57. Using the basic principles of quantum mechanics, it was shown that a fireball can have two quantum states - with and without ignited Quark-Gluon Plasma (QGP). With an increase of the collision energy of heavy ions, the probability of QGP ignition increases. At the same time, the probability of the formation of fireball without QGP ignition also remains nonzero even at nuclear collision energies that are much higher than the threshold QGP formation energy, which may be erroneously considered to be fixed and which is intensively sought in modern heavy ion accelerators. Thus, at SPS energy of heavy ion collisions \sqrt{s_{NN}} = 17.3 GeV, which is much higher than the assumed threshold energy of QGP formation in the region around or slightly above of \sqrt{s_{NN}} = 3 GeV, only half of the central collisions of heavy ions bring to the formation of a fireball consisted of deconfined matter (quarks and gluons), the remaining half of the collisions lead to the formation of a fireball from only hadronic matter (mesons, nucleons, hyperons etc.).
Uncertainty of Serum TSH and Thyroxine on Abbott Architect i1000sr from Internal Quality Control Data: Use in Results Interpretation and QC Frequency Planning
Authors: Mohamed Mokhtar Khelil
Published: October 2022

The minimum requirement for uncertainty estimation is to use only intermediate precision (Rw), especially for measurands lacking a reference measurement system such as thyroid functions tests (TFT). In this study, measurement uncertainty (MU) for TSH and FT4 from long-term internal quality control (IQC) data was estimated while reference change values (RCV) were calculated from estimated MU. Furthermore, intermediate precision (Rw) was used to establish appropriate risk-based QC frequency. Twenty fore months of third party IQC data were collected retrospectively, on the Abbott ARCHITECT i1000sr analyzer from INSTITUT PASTEUR OF MSILA laboratory, ALGERIA. The MU, RCV and sigma-metric were estimated simply from the intermediate precision (Rw), while a nomogram relating sigma performance to run size was used to establish QC frequency. The MU for the TSH and FT4 was 12% and 8% respectively. The U one-sided for the TSH and FT4 was 10%, 6.6% respectively. MU and U one-sided of TSH and FT4 met quality requirements for permissible uncertainty (pU %) and allowable total error (ATE %). When monitoring thyroid replacement therapy, an upward minimum change (RCV) of 54% and 22% or a downward of 35% and 18% in serum TSH and FT4 respectively, would be considered significant. Optimal QC strategy for serum TSH was selected to run 4 QC materials every 190 patients sample and to use a multi-rule (13s/22s/R4s/41s). Our results suggest that MU estimation from long-term IQC alone may be acceptable for TFT to assist physician in results interpretation and to establish appropriate QC frequency.
Multi-ion Based Modelling and Experimental Investigations on Consistent and High-throughput Generation of Micro Cavity Array by Mask Electrolyte Jet Machining
Authors: Wu Ming , Guo Zhongning , Qian Jun , Reynaerts Dominiek
Published: October 2022

The controllability and consistency in the fabrication of micro-textures on large-scale remains a challenge for existing production processes. Mask electrolyte jet machining (MEJM) is an alternative to Jet-ECM for controllable and high-throughput surface microfabrication with more consistency of dimensional tolerances. This hybrid configuration combines the high-throughput of masked-ECM and the adjustable flow-field of jet-ECM. In this work, a duckbill jet nozzle was introduced to make MEJM more capable of batch micro-structuring. A multiphysics model was built to simulate the distribution of electrochemical reaction ions, the cur- rent density distribution and the evolution of the shape of the machined cavity. Experimental investigations are presented showing the influence of the machining voltage and nozzle moving speed on the micro cavity. Several 35 ×35 micro cavity arrays with a diameter of 24.92 − 11.73 µm and depth of 15.86 − 7.24 µm are generated on 304 stainless steel.
Transformational Geothermal Fluids in the Upper Jurassic Carbonate Reservoir of the South German Molasse Basin
Authors: Schneider Jochen , Heine Florian , Heidinger Michael , Rosner Martin
Published: October 2022

The hydrochemical composition of the Upper Jurassic groundwaters in the South German Mo-lasse Basin (SGMB) indicates a heterogeneous and varying hydrogeochemical evolution, which contradicts previous flow model concepts. For this study, the data of 88 Tertiary, Cretaceous and Upper Jurassic groundwater samples were investigated for hydrochemical elements, 2H/18O-H2O isotopes, 87Sr/86Sr ratios as well as δ11B values. In addition, the geochemical composition, 87Sr/86Sr and δ11B values were analysed from depth-oriented Upper Jurassic rock samples to delineate water-rock interactions in the aquifer systems. Slightly elevated 87Sr/86Sr ratios of the carbonates compared to the typical signatures of marine Upper Jurassic carbonates indicate a synsedimentary radiogenic influence due to the erosion of the adjacent Bohemian Massif. However, these values cannot explain the significant higher Sr-isotope fingerprint of the groundwaters in the central SGMB. Different water types occur in the Upper Jurassic aquifer, primarily distinguished by the dominant cations, calcium or sodium with subclasses of the major anions. The calcium-dominated groundwaters occur mainly at the western and northern margins of the SGMB. The sodi-um-dominated ion exchange groundwaters instead dominate in the central and eastern SGMB. With increasing strontium content, the 87Sr/86Sr ratios of the Upper Jurassic groundwater samples either indicate a strontium uptake by carbonate of the host rocks, or a prevailing radiogenic sig-nature. This implies a basic interaction with terrestrial or marine Tertiary sediments. The results illustrate a downward transformational fluid flow systematic via the thick Tertiary sediment cover into the Upper Jurassic carbonate formation in the SGMB, highlighting a new understanding on the evolution of the Upper Jurassic groundwaters and a basin-wide recharge mechanism.
The Short and Long Run Impact of Population Growth and HIV Incidence on Economic Growth and Economic Development in Selected African Countries
Authors: Mwimba Thomas , Marialetta Telukhunoana Mhponyane , Wambui Karanja Esther , Ndzimandze Nomfundo
Published: October 2022

Africa is expected to have a lion’s Share in the world’s population growth by 2050. At the same time, the World Health Organisation (WHO) reported that roughly 3.4 percent (1/25) of African adults live with HIV making the contient the most severely affected by the HIV pandemic. Consequently, this study, the first of its kind, investigates the impact of population growth and HIV incidence on economic growth and economic development in Africa by utilizing the Pooled Mean Group (PMG) estimator on data from 1990 to 2020 across 29 countries. The results show that population growth has a postive long run impact on Gross Domestic Product (GDP) but has a negative long run impact on per capita GDP, albeit the effects are insignificant in the short run. The incidence of HIV has a negative long run impact on both GDP and per capita GDP although its effect is not significant in the short run. The study, therefore, calls for the advancement of family planning practices and the usage of contraceptives to simultaneously control population growth and curb the spread of HIV incidence. The study futher calls for African governments to increase budgetary allocations to the health and education sectors, as these policy perspectives have the potential of increasing the human capital stock and at the same time enhancing the health status of the work force for sustained growth and development.
A Proteomics Approach in Farm Animals’ Milk: A Comprehensive Analysis
Authors: Bouroutzika Efterpi , Proikakis Stavros , Theodosiadou Ekaterini K. , Katsafadou Angeliki I. , Valasi Irene , Tsangaris George T.
Published: October 2022

Milk is newborn’s food and an emulsion full of all necessary components for neonatal growth. Its consumption is worldwide and is the base for all dairy products. Because of the latter, many new technologies are growing, among them proteomics; in order to give new insights in milk’s compounds and to maximize the beneficial potential for consumers’ health. In this review, we aimed to gather data of proteomics studies for the majority of dairy animals and elucidate the role of milk bioactive compounds. Furthermore, special reference was made to milk fat globule membrane (MFGM) peptides and the result of thermal treatment in milk proteins. Finally, the proteomic approach regarding adulterations was included in the review.
A Linear SARS-CoV-2 DNA Vaccine Candidate Reduces Virus Shedding in Ferrets
Authors: Martins Mathias , Do Nascimento Gabriela M. , Conforti Antonella , Noll Jessica C.G. , Impellizeri Joseph A. , Sanchez Elisa , Wagner Bettina , Lione Lucia , Salvatori Erika , Pinto Eleonora , Compagnone Mirco , Viscount Brian , Hayward James , Shorrock Clay , Aurisicchio Luigi , Diel Diego G.
Published: October 2022

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), has caused more than 600 million cases and over 6 million deaths worldwide. Vaccination has been the main strategy used to contain the spread of the virus, and to avoid hospitalizations and deaths. Currently, there are two mRNA-based and one adenovirus vectored vaccines approved and available for use in the U.S. population. The versatility, low cost and rapid-to-manufacture attributes of DNA vaccines are important advantages over other platforms. However, DNA vaccination must meet higher efficiency levels for use in humans. Importantly, in vivo DNA delivery combined with electroporation (EP) has been successfully used in the veterinary field. Here we evaluated the safety, immunogenicity and protective efficacy of a novel linear SARS-CoV-2 DNA vaccine candidate for delivered by intramuscular injection followed by electroporation (Vet-ePorator™) in ferrets. The results demonstrated that the linear SARS-CoV-2 DNA vaccine candidate did not cause unexpected side effects, and was able to elicit neutralizing antibodies and T cell responses using a low dose of the linear DNA construct in prime-boost regimen, and significantly reduced shedding of infectious SARS-CoV-2 through oral and nasal secretions in a ferret model.
Observation of External Wounding on Green Ash (Fraxinus pennsylvanica Marshall) Trees Associated with Tree Injection Systems
Authors: Hauer Richard J. , Ball John J. , North Eric
Published: October 2022

Field observations of external wounds associated with two common tree injection methods compared open (plug-less) and sealed (plug) systems in green ash (Fraxinus pennsylvanica Marshall) trees . A wound from any cause within 1.37 meters above the ground was common with 28.8% of all trees. The open system had statistically fewer (p<0.001) trees with at least one wound (11.6% of trees) than the sealed system (47.4% of trees). The open system had fewer (P<0.001) wounds (0.17, 0.04 SE) per tree and a smaller (P<0.001) total wound area (25.5 cm2, 8.7 SE) per tree, compared to the sealed system wounds (1.14, 0.13 SE) per tree and the total wound area (99.7 cm2, 16.2 SE) per tree. The incidence of a tree with a wound(s) within 1.37 m above the ground was 7.2 times more likely with trees treated though the sealed system. Wounds in the sealed system were observed to appear to have a high rate of improper application of plugs, which was associated in 77% of the cases to explain the wounds. Implications of study results are further provided to best protect ash trees, while at the same time reducing the incidence external wounding on ash trees.
Immune Enhancement of Nanoparticle-Encapsulated Ginseng Stem-Leaf Saponins on Porcine Epidemic Diarrhea Virus Vaccine
Authors: Su Fei , Xu Lihua , Xue Yin , Xu Wei , Li Junxing , Yu Bin , Ye Shiyi , Yuan Xiufang
Published: October 2022

Porcine epidemic diarrhea virus (PEDV) causes severe enteric disease in pigs, particularly neonatal piglets. Attempts to develop a safe and effective vaccine have been unsuccessful. Ginseng stem-leaf saponins (GSLS), a promising oral adjuvant candidate, can improve intestinal immune responses in poultry and mice. However, the low stability limits the further use. Poly lactic-co-glycolic acid (PLGA), a biocompatible and biodegradable nanoparticle, have been widely used in biomedicine for stable and targeted drug delivery. In this study, we developed GSLS-PLGA nanoparticles (GSLS-NPs) and evaluated the mucosal adjuvant efficacy in vitro and in vivo. GSLS-NPs significantly enhanced antigen internalization and pro-inflammatory cytokine secretion by DC2.4 cells. Mice orally administered GSLS-NPs before intramuscular inoculation generated CD11b+CD8α- and CD11b-CD103+ dendritic cells in the spleen and draining mesenteric lymph nodes, respectively, which are the types mainly responsible for antigen presentation. Additionally, enhanced neutralizing and non-neutralizing antibody responses and expanded activities of specific effector and memory CD4+ and CD8+ T cells were also observed in mice immunized with PEDV vaccines plus GSLS-NPs compared to mice receiving the vaccines alone. Furthermore, GSLS-NPs showed a good safety profile and presented great advantages over GSLS aqueous solution. Collectively, our results highlight the potential of GSLS-NPs as a mucosal adjuvant and provide an attractive vaccination strategy for combatting PEDV. Further study is required to evaluate the efficacy of this mucosal adjuvant in swine.
Prevalence of Pathogenic Leptospira Spp. in Non-Volant Small Mammals of Hutan Lipur Sekayu, Terengganu, Malaysia
Authors: Shafie Nur Juliani , Abdul Halim Najma Syahmin , Zalipah Mohamed Nor , Md-Nor Shukor , Awoniyi Adedayo Michael , Costa Federico
Published: October 2022

Leptospirosis is an important zoonotic disease that is transmitted worldwide through infected small mammals such as rodents. In Malaysia, there is paucity of information on the animal reservoirs that are responsible for leptospirosis transmission, with only few studies focusing on leptospirosis risk in recreational areas. Therefore, in this study, we characterized the species composition and the prevalence of pathogenic Leptospira spp. in non-volant small mammals of Hutan Lipur Sekayu, Terengganu. We performed ten trapping sessions totaling 3,000 trapping efforts between September 2019 and October 2020. Kidney samples from captured individuals were extracted for the PCR detection of pathogenic Leptospira spp. Overall, we captured 45 individuals from 8 species (1.56% successful trapping effort), with 9 individuals testing positive for pathogenic Leptospira, that is 20% (n = 9/45) prevalence rate. Rattus tiomanicus (n = 22) was the most dominant captured species and was found to harbour the highest positive individual with pathogenic Leptospira (44.4%, n = 4/9). Despite the low successful trapping effort in this study, the result shows that the non-volant small mammals of Hutan Lipur Sekayu are capable of maintaining and transmitting pathogenic Leptospira, thus making this recreational area a potential infestation ground for leptospirosis.
Intelligent Passenger Frequency Prediction for Transportation Sustainability using Kalman Filter Algorithm and Convolutional Neural Network
Authors: Jimoh Onemanyin David , Ajao Lukman Adewale , Adeleke Oluwafemi Oyetunde , Kolo Stephen Sunday , Olarinoye Oyedeji Abdulwaheed
Published: October 2022

The passenger prediction flow is very significant to transportation sustainability. This is due to some chaos of traffic jams encountered by the road users during their movement to the offices, schools, or markets at earlier of the days and during closing periods. This problem is peculiar to the transportation system of the Federal University of Technology Minna, Nigeria. However, the prevailing technique of passenger flow estimation is non-parametric which depends on the fixed planning and is easily affected by noise. In this research, we proposed the development of a hybrid intelligent passenger frequency prediction model using the Auto-Regressive Integrated Moving Average (ARIMA) linear model, Convolutional Neural Network (CNN), and Kalman Filter Algorithm (KFA). The passengers’ frequency of arrival at the bus terminals is obtained and enumerated through the closed-circuit television (CCTV) and demonstrated using the Markovian Queueing Systems Model (MQSM). The ARIMA model was used for learning and prediction and compared the result with the combined techniques of using CNN-KFA. The autocorrelation coefficient functions (ACF) and partial autocorrelation coefficient functions (PACF) are used to examine the stationary data with different features. The performance of the models was analyzed and evaluated in describing the short-term passenger flow frequency at each terminal using the Mean Absolute Percentage Error (MAPE) and Mean Squared Error (MSE) values. The CNN-Kalman-filter model was fitted into the short-term series and the MAPE values are below 10%. The Mean Square Error (MSE) shows that the CNN-Kalman Filter model has the overall best performance with 83.33% of the time better than the ARIMA model and provides high accuracy in forecasting.
Copper-Catalyzed Homocoupling of Boronic Acids: A focus on B-to-Cu and Cu-to-Cu Transmetalations
Authors: Salamé Aude , Rio Jordan , Ciofini Ilaria , Perrin Lionel , Grimaud Laurence , Payard Pierre-Adrien
Published: October 2022

Controlling and understanding Cu-catalyzed homocoupling reaction is crucial to prompt the development of efficient Cu-catalyzed cross-coupling reactions. The presence of a coordinating base (hydroxide, methoxide) enables the B-to-Cu(II) transmetalation from aryl boronic acid to CuIICl2 in methanol, through formation of a mixed Cu-(μ-OH)-B intermediates. A second B-to-Cu transmetalation to form bis-aryl Cu(II) complexes is disfavored. Instead, organocopper(II) dimers undergo a coupled transmetalation-electron-transfer (TET) allowing the formation of a bis-organocopper(III) complexes readily promoting reductive elimination. Based on this mechanism some guidelines are suggested to control the undesired formation of homocoupling product in Cu-catalyzed cross-coupling reactions.
Financial Inclusion Strategy and Economic Growth in Nigeria: A Short-Run Empirical Analysis
Authors: Obi Callistar
Published: October 2022

It has been observed that most adult citizens, globally, are not enjoying financial services. They are financially excluded, especially rural dwellers. Monetary authorities initiated financial inclusion, with the aim of including all adult population who are excluded from financial services into the financial system at an affordable cost to meet their basic needs. Studies have shown that it encourages household savings and affects growth positively. Central Bank of Nigeria initiated financial inclusion in 2012 and commenced implementation in 2014. Given the short period of its implementation, this study ascertained the effect on economic growth in Nigeria. The study used time series data ranging from 2004 to 2021. The study covered the pre-inclusion period, through its implementation period. Ordinary Least Square technique was adopted for data estimation. Preliminary and post-estimation tests were also conducted. Despite the short period of the implementation of financial inclusion strategy, the OLS result affirmed that it positively affects economic growth. It was concluded that financial inclusion is a growth driver. It was recommended that Central Bank of Nigeria, in collaboration with commercial banks and microfinance banks, continue to enforce inclusion exercise in all rural communities, ensuring that women, youths, farmers, traders in the informal sector, are captured by the financial system. Also, Central Bank Nigeria should set up financial inclusion compliance committee at the Local Government levels, with a State Monitoring unit to ensure compliance.
Rutting Performance of Nano-Silica Modified C320 Bitumen: A Case study
Authors: Mashaan Nuha
Published: October 2022

Nanomaterials exhibit novel properties and profound attributes as an additive in asphalt binder modification. However, the application of nano-silica in asphalt binders and mixture modification is still limited and further research is required. Along these lines, in this work, nano-silica with a content from 2% to 8% and an increment of 2% were utilized in modifying the bitumen binder type C320, which is considered the most conventional type of bitumen used in Western Australia road asphalt mixtures. Various tests were performed to assess their properties including dynamic shear rheometer, penetration, softening point, and multiple stress creep recovery (MSCR) test. The extracted results revealed an increase in the strength and stiffness properties by lowering the penetration, improving the softening point, and increasing the complex shear modulus of all nano-silica modified bitumen samples. Interestingly, a relatively big content of nano-silica leads to a higher rutting resistance. Nevertheless, the rutting resistance was affected by the size of the nano-silica coated with the silane coupling agent. The ideal sample of nano-silica modified C320 was determined as NS-15nm (NS-A), which can improve the rutting resistance. Nevertheless, the rutting resistance of the modified asphalt mixtures needs to be further investigated in the future to elaborate on the impact of nano-silica as modified binders on the mechanical properties of Australian asphalt mixtures.
#OrthoTwitter: Blending Information, Education, and Entertainment Online
Authors: Chellamuthu Girinivasan , Muthu Sathish , Siddamanickam Siddeshwar
Published: October 2022

Background:

Twitter has become a part of every medical field, including orthopaedics. #OrthoTwitter is the hashtag commonly used for orthopaedic-related tweets. Researchers have assessed the impact of Twitter in orthopaedics, but no study has evaluated the individual tweets under #OrthoTwitter. The purpose of the present study was to determine the nature of the content and interactions under #OrthoTwitter and to analyze the usefulness of #OrthoTwitter.

Methods:

After a pilot study, an analysis of #OrthoTwitter tweets was conducted from May 1, 2021, to June 30, 2021. Data were extracted in 2 stages. In Stage I, data were manually extracted at 8 p.m. IST (Indian Standard Time) on alternate days. In Stage II, data were collected using the web-scraping tool Octoparse. Data were analyzed on the basis of 3 characteristics—topic, purpose, and format of the tweet—with each characteristic comprising 10, 6, and 7 categories, respectively. An association analysis was performed using SPSS software.

Results:

One thousand and twenty-three tweets were analyzed. Five hundred and fifty-three (54%) of the 1,023 tweets were from orthopaedic surgeons and 123 (12%) were from orthopaedic residents. Medical students aspiring to be orthopaedic surgeons contributed 31 tweets (3%). #OrthoTwitter was also used by non-orthopaedic departments, most frequently radiology. Tweets that were educational or informative were the most common, as compared with tweets of other purposes. Two hundred and forty-six (24%) of the 1,023 tweets were educational (e.g., discussions of cases or journals) and 368 (36%) were informative (e.g., conference announcements and advertisements). Notable tweet subcategories included those related to COVID-19 (71 tweets; 7%), those of a motivational nature (41 tweets; 4%), and those containing some type of graphic content (644 tweets; 63%), for the topic, purpose, and format characteristics, respectively. We noted significantly more likes for tweets with an educational purpose (p = 0.017) and for tweets with images (p < 0.001). We also noted a significant number of retweets of educational tweets (p < 0.001).

Conclusions:

#OrthoTwitter provides a unique environment in which education, news, collegial interaction, social responsibility, and entertainment thrive, making Twitter a virtual community. Tweets with an educational purpose and those that included images generated more interactions. Orthopaedic surgeons should consider using #OrthoTwitter in their orthopaedic-related tweets for a broader reach.
ESTIMATIVA DA IDADE APLICADA A INVESTIGAÇÕES ARQUEOLÓGICAS UTILIZANDO ESPECTROSCOPIA RPE – UMA REVISAO
Authors: Libonati de Azevedo Renata , Cavalcante Fernandes Danilo
Published: October 2022

A estimativa da idade utilizando dentes humanos é realizada por várias ciências. Enquanto na odontologia e antropologia forense o significado desta estimativa está associado à idade cronológica em indivíduos vivos ou mortos, na arqueologia o significado é outro, e reflete o tempo decorrido desde a formação do dente até a sua descoberta no sítio arqueológico, a chamada datação arqueológica. Diante do potencial uso da datação para identificação de corpos antigos (fossilizados) na área forense, o objetivo deste trabalho é abordar a estimativa da idade de dentes sob a perspectiva da arqueologia, por meio do principal método de datação utilizado: o da espectroscopia por ressonância paramagnética eletrônica (RPE). Com o intuito de verificar as principais aplicações deste método na datação de dentes humanos, foi realizada uma revisão da literatura. Os 18 artigos selecionados mostram que a espectroscopia RPE encontra-se consolidada como método de datação para dentes humanos e tem sido aplicada com sucesso nas últimas décadas, na solução de problemas de diversas pesquisas arqueológicas, ajudando a elucidar questionamentos acerca da dinâmica de ocupação, interações interespecíficas e extinção de várias espécies humanas que habitaram a Terra nas últimas centenas de milhares de anos.
TELEODONTOLOGIA E RESOLUÇÃO CFO-226/2020: ASPECTOS ÉTICOS E LEGAIS
Authors: De Carvalho Cotrim Fayla , Viana Pinto Paulo Henrique , Alves da Silva Ricardo Henrique
Published: October 2022

A Organização Mundial da Saúde (OMS) decretou em março de 2020, o estado de pandemia decorrente do novo Coronavírus (SARS-CoV-2). Nesse cenário, a teleodontologia se destacou como mecanismo de promoção da assistência odontológica durante o período mais crítico da pandemia. O presente estudo tem como objetivo apresentar, por meio de uma revisão de literatura, os aspectos éticos e legais pertinentes ao uso da teleodontologia no Brasil. A teleodontologia já era utilizada no Brasil antes da pandemia de COVID-19, porém não era regulamentada pelo Conselho Federal de Odontologia (CFO). Em 4 de junho de 2020 foi promulgada a Resolução CFO-226/2020, regulamentando o exercício da teleodontologia no país. A Resolução apresenta impasses e discussões quanto aos meios de assistência e suas vedações referentes a atuação dos profissionais. Conclui-se que a Resolução CFO-226/2020 reafirmou princípios éticos e legais quanto a prática odontológica descrita nas principais normas da classe e que, apesar das vedações apresentadas na Resolução CFO-226/2020, a mesma se configura como um guia específico para realização das atividades laborais odontológicas referentes à teleodontologia.
TÉCNICAS DE MARCAÇÃO DE PRÓTESES DENTÁRIAS: REVISÃO DA LITERATURA
Authors: Campos Edine Maria de Medeiros , Pascoal Ana Luísa de Barros , Emiliano Gustavo Barbalho Guedes , Duarte Antônio Ricardo Calazans
Published: October 2022

Indivíduos edêntulos representam um desafio na identificação humana, por isso, em 1931, a marcação identificadora de próteses dentárias foi proposta pela primeira vez, e várias técnicas e materiais têm sido testados ao longo dos anos. A marcação ou identificação de próteses é feita através da incorporação de materiais metálicos, não metálicos, microchips ou outros que são introduzidos no material da prótese removível, ou, ainda, pela marcação da superfície. O presente estudo teve como objetivo descrever as técnicas de marcação protética através de uma revisão narrativa da literatura com busca sistemática realizada nas bases de dados PubMed, Google Acadêmico e SciELO, além de uma busca manual nas referências dos trabalhos selecionados. É responsabilidade ética e legal do cirurgião-dentista auxiliar em investigações de identificação humana, assim, dado o amplo uso de próteses no Brasil, o valor de uma identificação, a relevância e comprovada eficiência em situações forenses, a marcação de próteses deve ser oferecida como opção a todos os pacientes.
Korelasi Kemampuan Mengelola Emosi dengan Perilaku Agresif Siswa SMA Negeri 5 Kota Kupang
Authors: Indrawan Putu Agus , Redo Carolina Y , Upa Muhamad D Pua
Published: October 2022

Penelitian ini bertujuan untuk mengetahui gambaran kemampuan mengelola emosi siswa, perilaku agresif siswa, dan menemukan hubungan antara kemampuan mengelola emosi dan perilaku agresif siswa di SMA Negeri 5 Kota Kupang. Penelitian ini menggunakan pendekatan kuantitatif dengan jenis penelitian korelasi. Penelitian ini dilaksanakan di SMA Negeri 5 Kota Kupang dengan jumlah populasi 1.296 orang dan sampel 93 orang. Teknik pengambilan sampel yang digunakan adalah teknik proportional stratified random sampling. Data dikumpulkan menggunakan instrumen skala psikologis kemampuan mengelola emosi dan angket perilaku agresif. Data tersebut dikelola menggunakan bantuan aplikasi SPSS. Hasil penelitian menunjukkan bahwa (1) secara umum siswa memiliki kemampuan mengelola emosi dengan kategori tinggi 62 atau 67%, kategori sangat tinggi 27 atau 29% siswa, kategori rendah 4 atau 4% siswa. (2) secara umum siswa memiliki perilaku agresif dengan kategori sangat tinggi 2 atau 2% siswa, kategori tinggi 13 orang atau 14% siswa, kategori rendah 43 atau 46% siswa, kategori sangat rendah 34 atau 38% siswa. Hasil pengujian hipotesis disimpulkan bahwa menunjukkan hubungan positif yang signifikansi antara kemampuan mengelola emosi dan perilaku agresif siswa SMA Negeri 5 Kota.
Studi Literasi Pembelajaran Pendidikan Agama Islam Anak Usia Dini
Authors: Nurhayati Nurhayati
Published: October 2022

Pendidikan anak usia dini dalam Islam adalah pendidikan yang berlangsung sejak anak-anak masih kecil. Islam menyebutkan bahwa seseorang itu dikatakan anak-anak, apabila ia belum mencapai akil baligh (dewasa) dan pendidikan diamanahkan kepada orang tua sebagai pendidik yang utama. Usia dini merupakan masa emas (golden age), karena pada usia dini ini anak-anaka mengalami pertumbuhan dan perkebangan yang sangat luar biasa mulai dari fisik, mental, pembentukan karakter, watak serta kepribadian. Oleh karena itu sangat penting sekali diberikan pendidikan agama sejak dini bertujuan bukanlah sekedar mengalihkan perilaku atau tabiat sebagai isi pendidikan akhlak, melainkan lebih merupakan suatu ikhtiar untuk menggugah fitrah insaniyah, sehingga peserta didik bisa menjadi penganut atau pemeluk yang taat dan baik serta bermoral. Dengan kata lain, pendidikan akhlak anak dalam Islam bertujuan agar peserta didik dapat membentuk dirinya menjadi insan kamil yang mempunyai akhlakul karimah dan dapat mengaplikasikan-nya di dalam kehidupan sehari-hari sebagai hamba Allah yang taat untuk menggapai ridha-Nya dalam kehidupan dunia dan akhirat. Dalam menanamkan pendidikan agama pada anak usia dini dapat diberikan  melalui beberapa langkah seperti keteladanan selalu mengucapkan rasa syukur atas nikmat yang Allah berikan serta mengenalkan ibadah terutama sholat, wudhu dan membaca do’a sehari-hari serta surat-surat pendek, bercerita mengenalkan ciptaan-ciptaan Allah tentang alam seisinya, nasihat dan pembiasaan yang bernuansa Islami agar terbentuk akhlakul karimah .
Semantic-based Vulnerability Detection by Functional Connectivity of Gated Graph Sequence Neural Networks
Authors: ŞAHİN CANAN BATUR
Published: October 2022

In computer security, semantic learning is helpful in understanding vulnerability requirements, realizing source code semantics, and constructing vulnerability knowledge. Nevertheless, learning how to extract and select the most valuable features for software vulnerability detection remains difficult. We establish a hypothesis that the source projects' vulnerable functions include the project-independent vulnerable patterns shared among vulnerabilities across different software projects. The trained Gated Graph Sequence Neural Networks (GGNNs) can be utilized to discover the said patterns in order to detect vulnerabilities on a target project. It is necessary to identify vulnerable programming patterns by considering the context. Therefore, we use functional connectivity (FC) based on Gated Graph Neural Networks as a learning representation of features to capture long-term dependency to understand a high-level representation of potential vulnerabilities to learn context-dependence. The experimental findings indicate that the suggested Model can select relevant discriminative features and achieve superior performance than benchmark methods.
Isolation and identification of Endophytic Actinobacteria from Citrullus colocynthis (L.) Schrad and their Antibacterial properties
Authors: Ali Aram R. , Bahrami Yadollah , Kakaei Elham , Mohamadzadeh Sara , Bouk Sasan , Jalilian Nastaran
Published: October 2022

Background: Antibiotic resistance poses a major threat to human health globally. Consequently, new antibiotics are desperately required to discover and develop from unexplored habitats to treat life-threatening infections. Microbial natural products (NP) are still remained as primary sources for the discovery of new antibiotics. Endophytic actinobacteria (EA) which are well-known producers of bioactive compounds could provide novel antibiotic against pathogenic bacteria. This research aimed to isolate EA from the Citrullus colocynthis plant and explore the antibacterial properties of their metabolites against pathogenic bacteria.
Results: The healthy samples were collected, dissected and surface- sterilized before cultured on four different selection media at 28°C. Six endophytic actinobacteria were isolated from Citrullus colocynthis plant. They were taxonomically classified into two family namely Streptomycetaceaeand Nocardiopsaceae, based on their colony morphological features, SEM and molecular identification of isolates (16S rDNA gene analysis). This is the first report on the identification of EA form Citrullus colocynthis and their antibacterial activity. Three of those were reported as endophytes for the first time. The strain KUMS-C1 showed 98.55% sequence similarity to its closely related strains which constitutes as a novel species/ strain for which the name Nocardiopsis colocynthis sp was proposed for the isolated strain. Five isolated strains had antagonist activity against S. aureus, P. aeruginosa, and E. coli. Among those, stain KUMS-C6 showed broadest spectrum of antibacterial activity against all test bacteria, whereas the strain KUMS-C4 had no antibacterial activity.
Conclusions: NPs have a long history of safe and efficient use for development of pharmaceutical products. Our study highlights that Citrullus colocynthis is an untapped resource for isolation of EA for which might provide new antibiotics. The screech for new antibiotics from EA could lead to chemical novelty and bioactivity. This study reveals the future of new antibiotic developments looks bright against multi-drug resistance diseases by mining under- or unexplored habitats.
Developing practice points for healthcare workers to optimise lymphoedema care in low and middle-income countries: a nominal group technique
Authors: Torgbenu Eric , Luckett Tim , Buhagiar Mark , Phillips Jane L
Published: October 2022

Background: Lymphoedema is a common, distressing, and debilitating condition affecting over 200 million people globally. While the World Health Organization has developed a Wound and Lymphoedema Management guidance document to support lymphoedema care in low- and middle-income countries (LMIC), it mainly focuses on lymphoedema caused by wounds and infectious filariasis and has limited content on lymphoedema diagnosis and assessment. Several lymphoedema clinical practice guidelines have been developed for high-income countries (HIC), but some recommendations are unlikely to be feasible in low-resource settings.
Aim:
To develop practice points for healthcare workers that optimise lymphoedema care in LMIC.
Methods: A nominal group technique (NGT) was undertaken to gain consensus on which content from HIC guidelines are important and feasible to include in practice points for LMIC, plus other important advice or recommendations. Participants included experts, clinicians, and volunteers involved in lymphoedema care in LMIC. The NGT followed five key stages: silent ‘ideas’ generation, round-robin rationale, clarification, refinement and verification. The first, fourth and fifth stages were completed via email, and the second and third during a video meeting. Practice points were divided into prevention, assessment, diagnosis, and management of lymphoedema in LMIC.
Results: Of 16 participants invited, 10 members completed stage 1 of the NGT (ideas generation), of whom six contributed to stages 2 (round-robin) and 3 (clarification). All those who completed stage 1 also completed stages 4 (refinement) and 5 (verification). Practice points unanimously agreed on included Complex Decongestive Therapy (CDT) and good skin care, with management to be determined by lymphoedema stage. For podoconiosis-endemic areas, the use of socks and shoes was identified as very important in the prevention of non-filarial lymphoedema and other lymphoedema-causing conditions. Participants indicated that diagnosing lymphoedema using the lymphoscintigraphy and Indocyanine green (ICG) fluorescent lymphography was not possible due to unavailability and cost in LMIC. Surgical procedures for lymphoedema management were unanimously eliminated due to the unavailability of technology, limited workforce, and expensive cost in LMIC.
Conclusion: The consensus-based practice points generated by this project provide healthcare workers with guidance on caring for people with lymphoedema in LMIC. Further development of workforce capacity is needed.
Kell Blood Group System: A Systematic Review and Meta-Analysis
Authors: Kausar Tasleem , Fatima Maham , Noureen Shumaila , Javed Shumaila , Abdulsattar Sana , Shahid Fareeha , Abiha Umme , Shakeel Rubina , Noureen Nadia , Maqbool Uzma , Tariq Nabeela , Sadiq Rehan , Islam Amjad
Published: October 2022

Background
Kell is highly immunogenic after ABO and Rh blood group system, and anti-Kell antibodies have been linked to hemolytic transfusion reaction and fetal hemolytic disease in newborns. The antithetic KEL1/KEL2, KEL3/KEL4, and KEL6/KEL7 antigens are expressed in the Kell blood group system. At least 36 antigens are carried on a single 93 kDa red-cell trans-membrane protein in the Kell blood system. This study aimed to review different literature on the kell blood group and associated phenotypes and to find out the epidemiology and frequency of different Kell antigens all over the world.
Methods
Epidemiological studies of Kell antigens (2000 to 2022) were extracted to capture all reported data of different kell genotypes/phenotypes from different populations. Different databases like Google Scholar, PubMed, JSTOR, Scopus, and Science Direct were accessed to download all the published data reporting different percentages of kell antigens.
Results
A total of 250 research papers and articles were downloaded; 60 studies met our inclusion criteria. Most of the research studies consisted of KEL1/KEL2, KEL3/ KEL4, and KEL6/KEL7. According to this meta-analysis, the prevalence of KEL1 and KEL3 are lower than KEL2 (100%) and KEL4 (100%). In all captured studies the prevalence of KEL1 ranged from 0 to 23.6%, KEL2 from 0 to 100%, KEL3 from 0 to 11.7%, KEL4 100%, KEL5 0%, KEL6 100%, and KEL7 was 97.31%.
Discussion
This is the first meta-analysis to check the occurrence of Kell blood antigens frequency and the spectrum of variants associated with it in populations of the world. This review will help to identify which is the common antigen of the Kell blood group system and how it can affect the person by disease associated with it.