bluuebunny/crossref_metadata_2025 huggingface dataset:
Gezeichnet – Tattoos und ihre soziokulturellen Bedeutungen
Authors: Bühler Eva , Ebertz Michael N.
Published: June 2023

Tattoos erzählen Geschichten – und das nicht nur auf individueller, sondern auch auf kollektiver Ebene. Basierend auf qualitativen Interviews mit tätowierten Personen untersucht diese Studie die Bedeutung von Tätowierungen in unserer heutigen Gesellschaft und zeigt, wie sich das Tattoo-Phänomen seit den 1990er Jahren gewandelt hat. Dabei wird deutlich, dass Tattoos nicht nur höchstpersönliche Bedeutungsträger sind, sondern auch Träger kollektiver Bedeutungen: Eine faszinierende Reise in die Welt der gezeichneten Häute unserer Zeit.
Urinary Cytokines as Potential Biomarkers of Mild Cognitive Impairment and Alzheimer’s Disease: A Pilot Study
Authors: Saiyed Nazia , Yilmaz Ali , Vishweswariah Sangeetha , Maiti Amit K. , Ustun Ilyas , Bartolone Sarah , Brown-Hughes Travonia , Thorpe Roland J. , Osentoski Tammy , Ruff Stacey , Pai Amita , Maddens Michael , Imam Khaled , Graham Stewart F.
Published: June 2023

Background:

Alzheimer’s disease (AD) is the most common form of dementia, accounting for 80% of all cases. Mild cognitive impairment (MCI) is a transitional state between normal aging and AD. Early detection is crucial, as irreversible brain damage occurs before symptoms manifest.

Objective:

This study aimed to identify potential biomarkers for early detection of AD by analyzing urinary cytokine concentrations. We investigated 37 cytokines in AD, MCI, and cognitively normal individuals (NC), assessing their associations with AD development.

Methods:

Urinary cytokine concentrations were measured in AD ( n = 25), MCI ( n = 25), and NC ( n = 26) patients. IL6ST and MMP-2 levels were compared between AD and NC, while TNFRSF8, IL6ST, and IL-19 were assessed in AD versus MCI. Diagnostic models distinguished AD from NC, and in-silico analysis explored molecular mechanisms related to AD.

Results:

Significant perturbations in IL6ST and MMP-2 concentrations were observed in AD urine compared to NC, suggesting their potential as biomarkers. TNFRSF8, IL6ST, and IL-19 differed significantly between AD and MCI, implicating them in disease progression. Diagnostic models exhibited promising performance (AUC: 0.59–0.79, sensitivity: 0.72–0.80, specificity: 0.56–0.78) in distinguishing AD from NC. In-silico analysis revealed molecular insights, including relevant non-coding RNAs, microRNAs, and transcription factors.

Conclusion:

This study establishes significant associations between urinary cytokine concentrations and AD and MCI. IL6ST, MMP-2, TNFRSF8, IL6ST, and IL-19 emerge as potential biomarkers for early detection of AD. In-silico analysis enhances understanding of molecular mechanisms in AD. Further validation and exploration of these biomarkers in larger cohorts are warranted to assess their clinical utility.
Predictive Value of Computed Tomography Following Neoadjuvant Chemotherapy for Muscle Invasive Bladder Cancer
Authors: Alam Syed M. , Martin Austin , McLeay Matthew T. , Smith Holly , Golshani Mahgol , Thompson Jeffrey , Sardiu Mihaela , Best Shaun , Taylor John A.
Published: June 2023

BACKGROUND:

Neoadjuvant chemotherapy (NAC) prior to radical cystectomy (RC) remains standard treatment for select patients with muscle-invasive bladder cancer (MIBC). Although computed tomography (CT) is often obtained prior to RC, its ability to predict pathologic response is poorly characterized.

OBJECTIVE:

The purpose of this study is to evaluate the predictive value of CT in assessing disease burden after NAC.

METHODS:

Patients with MIBC having received NAC prior to RC were identified. Pre- and post-NAC CT scans were reviewed by an abdominal radiologist. The correlation between pathologic complete response (PCR) and radiologic complete response (RCR) was determined as the primary aim. As a secondary aim, the correlation between pathologic partial response (PPR) and radiologic partial response (RPR) was determined. Logistic regression analysis was utilized to determine the predictive value of CT in determining disease burden at RC.

RESULTS:

A total of 141 patients were identified for analysis. PCR and PPR was achieved in 34% and 16% of patients, respectively. The positive predictive value of post-NAC CT was 53.5% for PCR and 28.8% for PPR. The negative predictive value of post-NAC CT was 73.5% for PCR and 46.2% for PPR. There was no significant association between RCR and PCR (OR 1.13, p = 0.67). Similarly, there was no meaningful association between RPR and PPR, lymph node involvement, or presence of extravesical disease.

CONCLUSIONS:

CT findings correlate poorly with final pathology at RC and should not be used to evaluate local disease burden.
The Inaction in Climate Change Adaptation and Mitigation in Sub-Saharan Africa: Some Policy and Legal Issues
Authors: Kooffreh B.E. , Anyatang Brian F.I. , Aminone Voke Tonia
Published: June 2023

This article seeks to examine as to how relevant environmental policy and legal principles deal with adaptation and mitigation challenges posed by climate change in Sub-Saharan Africa. It reviews and analyzes relevant provisions and processes of the UN Framework Convention on Climate Change (UNFCCC), the Kyoto Protocol, the Paris Agreement as well as other relevant principles such as common but differentiated responsibility and respective capability (CBDRRC) and binding emission reduction targets. The Sub-Saharan Africa’s attempts to adapt to and mitigate the effects of climate change are reviewed along with the challenges in the region including the urgent need for climate financing. It concludes by urging the creation of a separate department of climate change by the Sub-Saharan African States, the implementation of environmental liability insurance, the revitalization of the West African power pool project, and the creation of a robust financial mechanism under the Paris Agreement for adaptation and mitigation policies in the Sub-Saharan Africa.
Physical Activity for Cognitive Health: A Model for Intervention Design for People Experiencing Cognitive Concerns and Symptoms of Depression or Anxiety
Authors: Curran Eleanor , Palmer Victoria J. , Ellis Kathryn A. , Chong Terence W.H. , Rego Thomas , Cox Kay L. , Anstey Kaarin J. , Westphal Alissa , Moorhead Rebecca , Southam Jenny , Lai Rhoda , You Emily , Lautenschlager Nicola T.
Published: June 2023

Background: People experiencing cognitive concerns and symptoms of depression or anxiety are at risk for Alzheimer’s disease and dementia. We know physical activity can benefit cognition but understanding how to best support engagement is an ongoing challenge. Evidence-based conceptual models of factors underpinning physical activity engagement in target populations can inform intervention tailoring to address this challenge. Objective: This study (part of a pragmatic physical activity implementation trial) aimed to develop a specified model of physical activity engagement in people experiencing depressive or anxiety symptoms and cognitive concerns, to enable optimized dementia risk reduction intervention tailoring. Methods: We employed a qualitative design, triangulating data from three sources: semi-structured individual interviews with people experiencing cognitive concerns and mild to moderate depressive or anxiety symptoms; review of published evidence; and the Capability, Opportunity and Motivation system of behavior, an existing behavioral science model. Findings were integrated to develop a contextualized model of mechanisms of action for optimizing engagement. Results: Twenty-one participants were interviewed, and 24 relevant papers included. Convergent and complementary themes extended understanding of intervention needs. Findings highlighted emotional regulation, capacities to enact intentions despite barriers, and confidence in existing skills as areas of population-specific need that have not previously been emphasized. The final model provides specificity, directionality, and linked approaches for intervention tailoring. Conclusion: This study demonstrated that people experiencing cognitive concerns and symptoms of depression or anxiety require different interventions to improve physical activity engagement. This novel model can enable more precise intervention tailoring, and, ultimately, benefits for a key at-risk population.
The LEISURE Study: A Longitudinal Randomized Controlled Trial Protocol for a Multi-Modal Lifestyle Intervention Study to Reduce Dementia Risk in Healthy Older Adults
Authors: Treacy Ciara , Levenstein Jacob M. , Jefferies Annelise , Metse Alexandra P. , Schaumberg Mia A. , Villani Anthony , Boucas Ana P. , Hermens Daniel F. , Lagopoulos Jim , Andrews Sophie C.
Published: June 2023

Dementia is understood to arise from a mixed etiology, enveloping chronic inflammatory and vascular impacts on the brain, driven by a constellation of modifiable risk factors which are largely mediated by lifestyle-related behaviors. These risk factors manifest over a prolonged preclinical period and account for up to 40% of the population attributable risk for dementia, representing viable targets for early interventions aimed at abating disease onset and progression. Here we outline the protocol for a 12-week randomized control trial (RCT) of a multimodal Lifestyle Intervention Study for Dementia Risk Reduction (LEISURE), with longitudinal follow-up at 6-months and 24-months post-intervention. This trial integrates exercise, diet, sleep, and mindfulness to simultaneously target multiple different etiopathogenetic mechanisms and their interplay in a healthy older adult population (aged 50–85 years), and assesses dementia risk reduction as the primary endpoint. The LEISURE study is located in the Sunshine Coast region of Australia, which has one of the nation’s highest proportions of adults aged over 50 years (36.4%), and corresponding dementia prevalence. This trial is novel in its inclusion of mindfulness and sleep as multidomain lifestyle targets, and in its comprehensive suite of secondary outcomes (based on psychological, physical health, sleep activity, and cognitive data) as well as exploratory neuroimaging (magnetic resonance imaging and electroencephalography) and molecular biology measures. These measures will provide greater insights into the brain-behavioral underpinnings of dementia prevention, as well as the predictors and impacts of the proposed lifestyle intervention. The LEISURE study was prospectively registered (ACTRN12620000054910) on 19 January 2020.
Alteration of Cognitive Function in Aging and Alzheimer’s Disease Mice Is Related to Dysfunction of the Neuroimmune System
Authors: Jiang Wan-Rong , Wu Wei , Yang Li-Jie , Yang Wanzhexi , Tian Qing , Yao Zhao-Hui
Published: June 2023

Background: Both Alzheimer’s disease (AD) and aging have aging-related cognitive dysfunction with a high incidence. These neurological diseases cause serious cognitive problems in patients’ daily life. But the cognitive dysfunction mechanism in-depth of aging is far less known than that of AD. Objective: To reveal the different mechanisms of AD and aging-related cognitive dysfunction, we compared the mechanisms of aging and AD through analysis of differentially expressed genes. Methods: Mice were divided into four groups (3-month C57BL, 16-month C57BL, 3-month 3xTg AD mice, and 16-month 3xTg AD mice) according to genotype and age. The Morris water maze was employed to investigate the spatial cognition of mice. Differential expressions of genes of AD and aging were analyzed through RNA sequencing and GO, KEGG, Reactome analysis, and the dynamic change trend analysis. Microglia was stained with immunofluorescence and its numbers were counted for analysis. Results: The cognitive function of elderly mice were worse through testing with the Morris water maze. The cognitive function of 16-month 3xTg AD mice were worse than 16-month C57BL mice. The alteration tendencies of DE genes were uncovered, and microglia numbers increased during aging and AD progression through immunofluorescence. Conclusion: These results suggest that immune-related pathways might play a critical role in aging and AD-related cognitive dysfunction. Our research will help to provide some new potential targets for treating cognitive dysfunction in aging and AD.
Mitochondria-Related Candidate Genes and Diagnostic Model to Predict Late-Onset Alzheimer’s Disease and Mild Cognitive Impairment
Authors: Yan Ran , Wang Wenjing , Yang Wen , Huang Masha , Xu Wei
Published: June 2023

Background: Late-onset Alzheimer’s disease (LOAD) is the most common type of dementia, but its pathogenesis remains unclear, and there is a lack of simple and convenient early diagnostic markers to predict the occurrence. Objective: Our study aimed to identify diagnostic candidate genes to predict LOAD by machine learning methods. Methods: Three publicly available datasets from the Gene Expression Omnibus (GEO) database containing peripheral blood gene expression data for LOAD, mild cognitive impairment (MCI), and controls (CN) were downloaded. Differential expression analysis, the least absolute shrinkage and selection operator (LASSO), and support vector machine recursive feature elimination (SVM-RFE) were used to identify LOAD diagnostic candidate genes. These candidate genes were then validated in the validation group and clinical samples, and a LOAD prediction model was established. Results: LASSO and SVM-RFE analyses identified 3 mitochondria-related genes (MRGs) as candidate genes, including NDUFA1, NDUFS5, and NDUFB3. In the verification of 3 MRGs, the AUC values showed that NDUFA1, NDUFS5 had better predictability. We also verified the candidate MRGs in MCI groups, the AUC values showed good performance. We then used NDUFA1, NDUFS5 and age to build a LOAD diagnostic model and AUC was 0.723. Results of qRT-PCR experiments with clinical blood samples showed that the three candidate genes were expressed significantly lower in the LOAD and MCI groups when compared to CN. Conclusion: Two mitochondrial-related candidate genes, NDUFA1 and NDUFS5, were identified as diagnostic markers for LOAD and MCI. Combining these two candidate genes with age, a LOAD diagnostic prediction model was successfully constructed.
Intrapersonal and Interpersonal Disengagement Coping: Associations with Emotions of Youth At-Risk for Huntington’s Disease
Authors: Watson Kelly H. , Ciriegio Abagail E. , Pfalzer Anna C. , Snow Abigail , Hale Lisa , Diehl Spencer , McDonell Katherine E. , Claassen Daniel O. , Compas Bruce E.
Published: June 2023

Background: Families in which a parent has Huntington’s disease (HD) are faced with significant stressors that can contribute to difficulties in communicating together about illness-related concerns. Family members who use more disengagement coping strategies, including denial and avoidance, to deal with illness-related stressors may have the greatest challenges to effective communication. Objective: The current study examined the associations of intrapersonal and interpersonal disengagement coping responses with observed and reported emotions of adolescents and young adults (AYA) at genetic risk for HD. Methods: Families included 42 AYA (n = 26 females) ages 10 to 34 (M = 19 years, 11 months; SD = 7 years, 6 months) and their parent with HD (n = 22 females, M age = 46 years, 10 months; SD = 9 years, 2 months). Dyads participated in observations of communication and completed questionnaires about disengagement coping and internalizing symptoms. Results: Disengagement coping of AYA was unrelated to their observed and reported emotional difficulties (intrapersonal coping). However, there was evidence for the importance of interpersonal disengagement coping, as AYA’s negative affect was observed and reported to be highest when both AYA and their parents reported using high levels of avoidance, denial, and wishful thinking to cope with HD-related stress. Conclusion: The findings underscore the importance of a family-oriented approach to coping and communication in families affected by HD.
A novel decision-making method based on complex cubic q-rung orthopair fuzzy information
Authors: Ren Weijia , Du Yuhong , Sun Ronglu , Du Yuqin , Lü Mubo
Published: June 2023

To improve the accuracy of decision results in complex fuzzy environments, complex cubic fuzzy sets are studied, which can not only measure the periodicity of decision-making data, but also use interval values and single values to act together on the data. However, the fuzzy sets do not provide a reasonable explanation for some special cases of input arguments. Thus, the power average operator is used to eliminate the influence of extreme input arguments on decision results, and the Maclaurin symmetric mean operator considers the correlation between inputs in this paper. Firstly, we define the operation rules, distance measures, evaluation index function, and evaluation criteria in a complex cubic q-rung orthopair fuzzy environment. Then, some aggregation operators are proposed to aggregate complex cubic q-rung orthopair fuzzy numbers, and their desirable properties and some special cases are discussed. Next, we use the subjective and objective fusion method to determine the weight of attributes. Further, a multi-attribute decision-making method is established by combining aggregation operator, evaluation function, and weight determination method. Finally, the proposed method is applied to a specific quality evaluation problem, and the effectiveness and practicability of the proposed method are illustrated by other methods and parameter analysis.
The use of thematic context-based deep learning in discourse expression of sports news
Authors: Liu Yefei
Published: June 2023

Sports news is a type of discourse that is characterized by a specific vocabulary, style, and tone, and it is typically focused on conveying information about sporting events, athletes, and teams. Thematic context-based deep learning is a powerful approach that can be used to analyze and interpret various forms of natural language, including the discourse expression of sports news. An application model of sign language and lip language recognition based on deep learning is proposed to facilitate people with hearing impairment to easily obtain sports news content. First, the lip language recognition system is constructed; next, MobileNet lightweight network combined with Long-Short Term Memory (LSTM) is used to extract lip reading features. ResNet-50 residual network structure isadopted to extract the features of sign language; finally, the convergence, accuracy, precision and recall of the model are verified respectively. The results show that the loss of training set and test set converges gradually with the increase of iteration times; the lip language recognition model and the sign language recognition model basically tend to be stable after 14 iterations and 12 iterations, respectively, suggesting a better convergence effect of sign language recognition. The accuracy of sign language recognition and lip language recognition is 98.9% and 87.7%, respectively. In sign language recognition, the recognition accuracy of numbers 1, 2, 4, 6 and 8 can reach 100%. In lip language recognition, the recognition accuracy of numbers 2, 3 and 9 is relatively higher. This exploration can facilitate hearing-impaired people to quickly obtain the relevant content in sports news videos, and also provide help for their communication.
Riemann Hypothesis on Grönwall's Function
Authors: Vega Frank
Published: June 2023

Grönwall's function \(G\) is defined for all natural numbers \(n>1\) by \(G(n)=\frac{\sigma(n)}{n \cdot \log \log n}\) where \(\sigma(n)\) is the sum of the divisors of \(n\) and \(\log\) is the natural logarithm. We require the properties of extremely abundant numbers, that is to say left to right maxima of \(n \mapsto G(n)\). We also use the colossally abundant and hyper abundant numbers. There are several statements equivalent to the famous Riemann hypothesis. We state that the Riemann hypothesis is true if and only if there exist infinitely many consecutive colossally abundant numbers \(N< N'\) such that \(G(N)< G(N')\). In addition, we prove that the Riemann hypothesis is true when there exist infinitely many hyper abundant numbers \(n\) with any parameter \(u > 1\). We claim that there could be infinitely many hyper abundant numbers with any parameter \(u > 1\) and thus, the Riemann hypothesis would be true.
A Strategy for Developing Outreach-oriented Small Groups for Millenial Students at Georgia-Cumberland Academy Church
Authors:   ,   Andrews University, Hudson Greg
Published: June 2023

Problem Millennial students at Georgia-Cumberland Academy (GCA) are not being inspired and equipped to actively engage in community outreach. GCA is a boarding school with 80% of students having homes in other locations, limiting their opportunity to develop connections with any local community, both at home and at school. The result is that students are graduating without needed skills to spiritually interact with their community and to share their faith in Jesus in meaningful ways. About 60% of Adventist youth are leaving the church, and part of the problem may be their lack of connection to the outreach ministries of the church. Method A strategy for developing a church-wide system of outreach-oriented small groups was developed to provide Millennial students the opportunity to grow in community and to be inspired and equipped for outreach involvement. Characteristics of the Millennial generation were researched, along with successful small group strategies. Over four semesters during two school years, leaders were trained, group members were recruited, and outreach opportunities were developed based on an investigation of community needs. A Group Leader Training Series video curriculum was developed, along with Reach the World small group studies. Student attitudes regarding the impact of small groups on areas of their spiritual life were evaluated via surveys. Results A wide variety of affinity-based GROWgroups were formed with both GCA students and GCA Church members leading and participating. GROWgroup participants were involved in outreach both as groups and as individuals to meet the needs of the community. A majority of students that participated indicated that the GROWgroups were beneficial in the development of their spiritual life, their social interaction, and their attitude toward outreach. Conclusions Based on survey results and continuing small group interactions, the outreach-oriented small groups did have a perceived positive impact on inspiring and equipping for community outreach. Further study is recommended as to optimal group formats, outreach initiatives, and characteristics of future generations.
A Strategy To Increase Devotional Reading Of Ellen G. White's Books On The Bible Story At the Augusta First Seventh-Day Adventist Church
Authors:   ,   Andrews University, Boles Bobby
Published: June 2023

Problem Some members of the Augusta First Seventh-day Adventist Church felt the writings of Ellen G. White were irrelevant and thus had no influence in their spiritual life. The church members had dismissed her writings in their spiritual journeys and instead read the works of more contemporary authors. This group seemed to be apathetic to the matter of Ellen White as a prophet, and some avoided her written work all together. A contributing factor to this indifference might have been a lack of devotional reading of her books on the Bible story. By addressing this lack of devotional reading, I thought some might find Ellen G. White’s writings more relevant. Method A strategy was implemented to preach a series of sermons, implement small group discussions and create a supplemental reading plan to effect changes in the reading habits and patterns of the members of the Augusta First Seventh-day Adventist Church regarding their reading of Ellen G. White’s writings on the Bible. Patriarchs and Prophets was the book of choice, and a reading plan was shared with members of the congregation to guide them in their regular reading. A survey conducted before and after the sermon series was used to gauge changes in reading behavior. Results The overall reading of Ellen G. White’s works on the Bible story increased during the course of the project. Although attitudes toward Ellen G. White as a prophet remained unchanged, there was in fact a significant increase in the congregation’s reading of Patriarchs and Prophets. There were only slight changes and impacts on the congregation’s overall devotional patterns or in their Bible reading habits because of the sermon series. A positive result of the project was getting those who had never read Ellen G. White to give her a try. A shift in reading patterns of the congregation was demonstrated from non-Seventh-day Adventist Christian writers to the works of Ellen G. White. Conclusions The project was a success because the key goal was achieved. At the end of the project, more people within the congregation were reading the works Ellen G. White wrote about the Bible story and there was a significant increase in those reading Patriarchs and Prophets. More research is merited and needed in the area of understanding reading patterns within the works of Ellen G. White and who is reading them. There is a glaring absence of research in the area of seeking to understand potential benefits and effects of reading the writings of Ellen G. White.
A Strategy for Planting Missional Churches to Include and Disciple the Postmodern People in the South of Brazil
Authors:   ,   Andrews University, Gardino Natal
Published: June 2023

Problem In spite of the fact that the Seventh-day Adventist Church is growing in Brazil, the traditional evangelistic methods have not significantly reached people with a postmodern worldview, who (in this country) are generally younger, wealthier, and more educated. This present study was to mobilize the churches in the South of Brazil with information and strategies to include postmodern people in their evangelistic efforts both in the local church and in new planted churches as well. Method Curitiba Central Church was informed about the reality of the contemporaneous worldview, and leaders of the church and volunteers were trained, making the members and leaders of church departments more concerned about adapting their language and approach as much as possible within the limits of a traditional church, to reach postmoderns. Then a plan was made to plant a new church from within Curitiba Central, which would be focused specifically on including postmodern people, who are very unlikely to attend a conventional church at first. The new church plant was open every day and featured different events for the good of the community. The worship services had their place every Saturday morning, as well as Sundays and Wednesdays at night, and they consisted basically of three or four worship songs, prayer and the presentation of the Bible principles for the everyday life. Two different Bible classes were always available during the week for those who wanted more information. Results At the end of two years, the new church plant, which began with 39 trained members from the Curitiba Central Church and volunteers from other churches as well, baptized 26 people and counted 134 members. Though these numbers may not be much impressive in Brazil, the profile of the people baptized certainly is for being in the difficulty range of postmodern-prone people in Brazil: young adults and formally educated people. When considering the proportions, the new church plant has much more members in this category than any other church in the local Union Conference (although less than churches on university campuses). And these members are constantly trained to keep this configuration increasing by always inviting their friends and colleagues to the church community. Conclusions Church members in Brazil must learn about the reality of the postmodern reality and learn how to include people with this worldview in their evangelistic efforts. The local church can be adapted as much as possible in order to make their programs more interesting through the use of clear language, relevant lectures, more interaction with people, and the creation of different new ministries to involve every member in active services to the community. Planting new churches is also very important to reach and include people who would normally never attend a traditional church.
Improving the Lifestyle of Andrews Korean Seventh-day Adventist Church Members
Authors:   ,   Andrews University, Park Myung Do
Published: June 2023

Problem The Andrews Korean Seventh-day Adventist church in Berrien Springs, Michigan has holistic lifestyle problems that are on the rise. Church members are experiencing health issues such as cancer, high blood pressure, diabetes, osteoporosis, and insomnia. In observing dietary patterns, it was noticed that some of our members do not bother to ascertain the content of the food being eaten. Other members have express the desire to learn about a healthy lifestyle. Purposeful attention to this need of the church is necessary. As a church community comprised of mostly pastors, university students and their families it is time to advocate for lifestyle changes within the congregation. Although these students and their families are custodians of the Adventist health message, both here in the United States and in South Korea, most of these families do not follow or practice the health message as taught by the Seventh-day Adventist Church. This lack of practicing the health message is partially due to a lack of understanding it. Method This study used a survey instrument designed and developed to identify the importance of the need for healthful living education among the Andrews Korean Seventh-day church members in Berrien Springs, Michigan. Focus group interviews were also conducted to determine the opinions of the Andrews Korean church members with regard to implementing NEWSTART health seminars in the church’s ministry roster. Results The NEWSTART program ministry is synonymous with having a healthy lifestyle. Thus, the Andrews Korean members’ awareness of the need for having healthy lifestyles was shown to have increased with introduction of the NEWSTART program ministry. The pastors became more aware of the necessity of this program ministry and they had an increased sense of responsibility for the health message a little more so than the church members. The program showed that both pastors and members generally believe that Adventism does have a relatively positive influence on their practice of healthy lifestyles. They also believe that many Adventists teachings are related to NEWSTART ministry as seen in the Bible and Ellen G. White’s writings. Conclusion The findings of this study showed that health education and awareness through NEWSTART needs to be developed into a regular ministry at Andrews Korean church. This would further assist church members in increasing their knowledge of living healthy lifestyles so that they would be able to positively influence their church and community with examples of healthy living. Continuous education is highly recommended as an approach to creating a ministry of healthy living awareness based on the dynamic healthrelated message of the Seventh-day Adventist Church.
A Strategy for Discipleship of New Members at the Mount of Olives Seventh-day Adventist Church
Authors:   ,   Andrews University, Coleman Michael
Published: June 2023

Problem There was no discipleship strategy for new members at the Mount of Olives Seventh-day Adventist Church. Although the majority of new converts remained with the congregation, the church lacked a clear plan for nurturing the spiritual growth and leadership development of its new members. Method A strategy was developed in harmony with the practices and principles of biblical discipleship found in the New Testament and described in academic literature. It entailed the development of new members, particularly, and the entire congregation in general, by addressing the following four areas: spiritual nurturing, evangelism, leadership development, and stewardship/financial management. The strategy utilized traditional arenas in the church such as Sabbath worship service, Bible Class, Sabbath School, Prayer Meeting, and Revival Meetings to facilitate discipleship in the four dimension mentioned above. It also provided for the establishment of small groups, workshops, and training sessions in order to equip new members and the greater portion of the church. A combination of quantitative and qualitative measures was used to evaluate the effectiveness of discipleship strategy: namely, a questionnaire, a focus group, and an analysis of the church membership records. Results The discipleship strategy had a positive impact on the spiritual growth, leadership development, and retention rate of new members at the Mount of Olives Seventh-day Adventist Church. Conclusion In the process of developing, implementing, and evaluating the project, I have grown personally and professionally. I have also enjoyed the opportunity to engage reflectively with new members and the congregation at large in the mission of evangelism, spiritual growth, and leadership development—the essence of discipleship. The discipleship intervention had a positive influence on the spiritual growth and leadership development of the new members. However, this strategy would have been more effective if it had delineated various levels of competencies that the new members needed to reach and also provided for a rite of passage celebration at each level.
Development and Implementation of a Community-Based Health Evangelism Strategy at Fellowship Seventh-day Adventist Church in Tallahassee, Florida
Authors:   ,   Andrews University, Ricardo Daphnis
Published: June 2023

Problem The Fellowship Seventh-day Adventist church desired to reach its community but did not have a strategic plan on how to do so. The lack of a strategic plan hindered the effectiveness of the church in making an impact in its neighborhood and left the members with a sense that they were not making a difference in their community. Initial observations done through formal talks with church leaders suggested that health ministry was a focus where their church had a strength and was a means by which to reach the neighborhood. Method The methods used were to develop a team that analyzed data from a recent community health needs assessment, planned and implemented a health ministry initiative that targeted the local community, then tracked and evaluated the initiative whose aim was to support the church’s overall mission in the neighborhood so that individuals could also be made aware of the ministry the church provided to them. - Results Findings from the project were a list of new ideas regarding how to reach the local community; a record of community needs; a plan to prioritize and meet selected needs; a change in the health profile of participants engaged in the 8-week health series; and an increase in new members to the church. Conclusion The evidence showed that a strategic plan assisted the health ministry in developing a new identity and giving the church a missional direction for its community. Utilization of this ministry gift gave the church a renewed emphasis in its community outreach. The church realized it had a strength in the area of health evangelism. We can therefore conclude that the church did make an important contribution in the area of health evangelism; and that other churches can use this plan to make a similar impact in their communities.
A Strategy for Launching a Missional Ministry in the All Nations Seventh-day Adventist Church of Saint Petersburg, Florida
Authors:   ,   Andrews University, Mills John
Published: June 2023

Problem Based upon my pastoral observation, there was a lack of understanding among a majority of the board members of the All Nations Seventh-day Adventist Church regarding what it meant to be a missional team in service for Jesus Christ. As leaders of departments in particular, and the church, in general, the board members were more driven by the notion of putting on a quality program, than by the idea of a missional focus for all activities. Their influence made the work of ministry less effective than it could have been and more burdensome for their fellow leaders and members of the church. Method Over the period of 18 months ending in September 2017, the board members were engaged in a process of leadership development which was organized in two segments: eight and ten months consecutively. In the first segment (theoretical), board members were taught various aspects of leadership, the missional church, and how to acquire, study and use, the demographic information of their city. In the second segment (practical), board members along with regular members of the church conducted a community survey which helped them to understand better the needs of their community. The results of the survey were studied in concert with that which was taught in the first segment. This process informed the organization and implementation of the ministry for their community. Results There was a willingness among a majority of the All Nations board members to participate in a missional ministry endeavor. Some board members were more inclined to participate in the practical portions of such an endeavor, as opposed to advancing through a theoretical phase of personal development. Of the 17 regular attendees to board meeting, nine were willing participants in the project process from beginning to end. Seven of the nine completed both a pre-and post-project questionnaire. These assessment tools indicated varying levels of development achieved by some of the board members. The project process found its completion in the implementation of a ministry which benefits their community named "Blessing for Babies Ministry." It was adopted by the church as a whole as part of its ongoing community efforts. Conclusions Missional ministry endeavors and development of church leaders can be achieved if these processes are guided with pastoral intentionality. Faithful transformational pastoral leadership is necessary within the life of a congregation. The church that is transformational will also be missional. Inasmuch as God calls His people to participate in His mission to the world, His purpose is to transform people's lives through the gospel of Jesus Christ. Blessing for Babies Ministry is helping to transform the lives of babies and their mothers.
ОБРАЗ ЗЛОЧИННОСТІ У НАУКОВО-ФАНТАСТИЧНІЙКОНФІГУРАЦІЇ МАЙБУТНЬОГО
Authors: ЛИТВИНОВ О. М. , СПІЦИНА Г. О.
Published: June 2023

In the criminological context, the question of the destructiveness of crime, to which science fiction appeals, is considered. It, determining the "intention" of future crime, tries to warn society with its inherent figurative means about the special nature of the destructive for the individual and society opportunities for future crime. However, these opportunities are related to the active "context" of modernity, due to scientific and technological progress.
АКТУАЛІЗАЦІЯ НОВИХ СМИСЛІВ АКАДЕМІЧНОГО КУРСУ «КРИМІНОЛОГІЯ» ЗА ЗАГАЛЬНОЮ РЕДАКЦІЄЮ О. М. ЛИТВИНОВА З ПОЗИЦІЙ НАВЧАЛЬНО-НАУКОВОЇ ТА ДУХОВНО-ЦІННІСНОЇ СКЛАДОВОЇ
Authors: КРІЦАК І. В.
Published: June 2023

The article is a reviewand review article and is devoted to the description of individual substantive components of the academic course "Criminology" edited by A. N. Litvinov (2018). Attention is focused on the scientific and methodological foundation of this work. The genesisand stages of formation of the scientific criminological school of the Kharkiv National University of Internal Affairs are briefly defined. The development of this school naturally predetermined the appearance of this publication, which is undoubtedly recommended for use in the educational process and scientific activities.
Tumor desmóide intraperitoneal
Authors: Furtado José Pio , Pitrez Fernando A. , Oliveira João Regis , Scholl João G. , Farias Enelruy , Wojcicki Filho Zygmunt
Published: June 2023

Os autores, a propósito de um caso de tumor desmóide intraperitoneal operado no Hospital Santa Rita/ISCMPA, apresentam os aspectos patológicos e terapêuticos desta intrigante neoplasia classificada como pertencente ao grupo das fibromatoses. Tal neoplasia foi achado intra-operatório de laparotomia por volumosa massa abdominal, que redundou na exérese ampla de um grande tumor de aspecto homogeneamente maciço e nacarado, apenas laxamente aderido às vísceras circunjacentes. Na formulação do diagnóstico diferencial os autores sugerem que sua eventual ocorrência deva ser lembrada, marcadamente na vigência de situações clínicas similares.
Etiopatologia da leucemia/linfoma T do adulto (HTLV-I+) e incidência no Brasil
Authors: Pombo de Oliveira Maria S. , Esteves Claudete , Gollner Angela Maria , Carvalho Silvia Maia Farias de
Published: June 2023

Desde o descobrimento e caracterização do retrovírus (HTLV-i) e a sua associação com algumas neoplasias de células T periféricas, muitos avanços foram alcançados quanto aos aspectos etiopatológicos da leucemia/linfoma T do adulto (LLTA). Estudos soroepidemiológicos anti-HTLV-I realizados em diversas partes do mundo demonstraram que: HTLV-I é o agente etiológico da LLTA e da paraparesia espástica tropical (TSP); LLTA tem uma característica peculiar que é a forma geográfica da incidência da doença; na sua forma clínica mais freqüente, a LLTA pode apresentar as mesmas características dos linfomas cutâneos. Com o objetivo de divulgar os aspectos clinico patológicos dessa doença descrevemos a nossa experiência, ao estudar 21 casos de LLTA diagnosticados no Laboratório de Marcadores Celulares (CEMO) selecionados entre 260 casos de doenças linfoproliferativas crônicas, ao mesmo tempo que fazemos uma revisão de literatura sobre os avanços alcançados nas pesquisas dessa doença.
Estesioneuroblastoma. Relato de caso em nasofaringe e revisão da literatura
Authors: Venegas Luis Fernando de Paiva , Greggianin Lauro José , Kruter Décio Wainberg , Cerski Carlos Thadeu Schmidt , Brunetto Algemir Lunardi
Published: June 2023

O estesíoneuroblastoma (neuroblastoma olfatório) é um tumor raro do epitélio olfatório. Seu curso clínico habitual é caracterizado por crescimento lento e pela tendência a recidivar localmente. Neste relato é apresentado um caso de estesíoneuroblastoma em uma adolescente de 13 anos de idade, cujas características principais foram o sítio incomum de localização do tumor primário em nasofaringe, seu curso clínico rapidamente progressivo e dificuldade diagnostica. Nosso objetivo é chamar atenção para a existência desta neoplasia incomum e discutir seus aspectos mais relevantes, baseados em ampla revisão da literatura.
Tumor de pequenas células intra-abdominal desmoplásico com diferenciação divergente. Relato de caso e revisão da literatura
Authors: Pereira Emilio Marcelo , Maeda Sueli Aparecida , Domingues Maria Aparecida , Müller Sérgio Pizoni , Almeida Aiulca , Dalri Júlio , Schmitt Fernando Carlos
Published: June 2023

Um tipo distinto de tumor maligno de pequenas células tem sido descrito devido a sua peculiar localização intra-abdominal com predileção para envolvimento pélvico. Alguns autores têm designado este tumor como tumor intra-abdominal de pequenas células com diferenciação divergente. Esse tumor tem um perfil imuno-histoquímico peculiar, que é a co-expressão de marcadores musculares, epiteliais e neuroendócrinos. Este artigo descreve um caso de paciente do sexo masculino de 17 anos, com tumor abdominal apresentando características clínico-morfológicas e imuno-histoquímicas semelhantes às descritas para esta nova entidade. Uma revisão da literatura é também apresentada.
Qualidade da imagem em mamografia
Authors: Peixoto João Emílio
Published: June 2023

Quando comparada com as demais radiografias simples, a imagem radiográfica da mama é a que requer o mais alto padrão técnico na sua execução. Isto se deve à própria estrutura dos tecidos que compõem o órgão (tecidos de densidades muito semelhantes) e à geometria bastante particular com que ele é radiografado (compressão e localização rigorosas e uso de ampliação). Além disso, como o exame radiográfico da mama é um dos métodos utilizados no diagnóstico precoce do câncer, é necessário que seja realizado dentro de um nível bastante reduzido de risco decorrente da radiação. Desta forma, a exposição de mulheres sadias para o exame radiográfico da mama requer que o risco seja o mínimo compatível com uma imagem de alto padrão de qualidade.
Programa de certificação da qualidade de serviços de mamografia
Authors: Koch Hilton A. , Duarte Dakir Lourenço , Peixoto João Emílio
Published: June 2023

Torna-se necessário que os Serviços de Mamografia satisfaçam os critérios de qualidade, imagem e dose de radiação estabelecidos como referência. Neste contexto, o Colégio Brasileiro de Radiologia e a Comissão Nacional de Energia Nuclear estabeleceram o Programa de Certificação da Qualidade de Serviços de Mamografia. Este programa oferece aos radiologistas a oportunidade de atestar a qualidade dos seus serviços quanto aos aspectos de equipamento de raios X, qualificação da equipe técnico-radiologista, controle de qualidade, qualidade de imagem e dose de radiação.
Perbandingan Teknik Zikir Tarekat dan Teknik CBT Sebagai Terapi Depresi (Studi Pemikiran al-Sya'ra>ni dalam al-Anwa>r al-Qudsiyah dan Teknik CBT Made Simple Nina Josefowitz)
Authors: Rosidi Rosidi , Syatori Ahmad
Published: June 2023

Teknik CBT (Cognitive Behavioral Therapy) banyak diterapkan dalam penanganan penderita depresi, demikian pula zikir diyakini memiliki fungsi terapi selain fungsi-fungsi lain yang lebih populer. Penelitian ini bertujuan mengkomparasikan teknik CBT Made Simple Nina Josefowitz dan konsep teknik zikir Imam al-Sya’ra>ni> dalam kitab al Anwa>r al Qudsiyyah tentang fungsi keduanya sebagai terapi penanganan depresi. Berdasarkan hasil analisa dengan metode induktif, konten analisis dan komparatif, penelitian ini menghasilkan temuan adanya persamaan dan perbedaan konsep teknik zikir tarekat dalam kitab al-Anwa>r al-Qudsiyyah dengan teknik CBT Made Simple sebagai terapi penanganan depresi. Diantaranya ialah optimalisasi keduanya dalam hal sama-sama mengandalkan kualitas komunikasi, namun komunikasi dalam zikir tarekat cenderung lebih kompleks, terbentuk antara murid dengan murshid berlanjut kepada para shaikh-shaikh dalam jalur silsilah tarekat, kepada Rasulullah Saw. hingga sampai kepada Allah, sedangkan komunikasi dalam teknik CBT Made Simple hanya terbentuk antara klien dan terapis yang menangani saja. Dengan demikian zikir dengan teknik yang telah ditentukan lebih berpengaruh terhadap penderita depresi dibandingkan dengan teknik CBT Made Simple, meskipun dalam beberapa hal teknik ini memiliki kelebihan.