bluuebunny/crossref_metadata_2025 huggingface dataset:
SOCIO-PSYCHOLOGICAL ASPECTS THE MOTIVATION PROCESS IN THE ORGANIZATION. MOTIVATION APPROACHES TOOLS TO STIMULATE STAFF
Authors: Stefanova Sonia
Published: February 2020

The focus of this report is on the socio-psychological aspects of the motivation process within an organization, as well as on motivational approaches and tools for staff incentives. Because motivation deals with the questions "why" of behavior, it refers to the internal states of the body that lead to provocation, perseverance, energy provision, and direction of behavior. In this sense, first of all, in understanding the level of employee motivation, it is important to know the basic theoretical assumptions related to motivation and some aspects related to human behavior, as well as the values and beliefs that mediate behavior (i.e., the constructs that sit on the path between need and satisfaction). Knowledge of staff motivation helps the manager to navigate its complex nature, to trace the way and the reasons for its occurrence or absence, as well as to understand its strong points. Consideration of motivation, as a relatively distinct system, would allow to identify and relatively accurately evaluate its elements, to trace the relationships between them, and finally to learn the manager to recognize and manage the complex relationships between the overall behavior of the individual and his or her parts.
Feledésbe merült epizódok Hans Scharoun alkotói periódusai 1945 előtt
Authors: Nagy Iván , Karlovecz Ádám
Published: February 2020

Hans Scharoun (1893–1972), német modernista építész, munkásságát az utókor jellemzően az ún. organikus modern irányzathoz társítja. Egyedi életútját nagyban befolyásolta a viharos 20. századi európai történelem. Számos rendkívüli alkotása ellenére életműve még mindig nem kellőképpen feldolgozott, illetve megfelelően kiértékelt, az összkép vele kapcsolatban csak lassan válik teljessé. A földrajzi közelség ellenére munkáinak jelentős része magyar viszonylatban nem kellően, vagy egyáltalán nem ismert. Scharoun életpályájának korai, 1933 előtti szakasza meghúzódik a II. világháborút követő rendkívül termékeny és jól ismert időszakának árnyékában, annak ellenére, hogy fiatalon is számos jelentős alkotása született. A két periódus közötti bő évtized történései, az 1933 utáni évek pedig sokáig homályban maradtak, az első ezzel is foglalkozó publikáció2 csak 1978-ban jelent meg. Nem meglepő, hogy a róla kialakult összkép leegyszerűsítő. Írásunkban arra teszünk kísérletet, hogy Scharoun életművének, annak periódusainak megítélését árnyaljuk, korszakait a történelem tükrében és épületeinek vizsgálataival újraértelmezzük.
Zárszó
Authors: Pazár Béla
Published: February 2020

Bauhaus. Ortodox modern hívők szentként tisztelt műhelye, gyűlölet, megvetés, olykor cinikus gúny tárgya egyszerre. Ennek oka talán az, hogy száz évvel megalakulása után sem ismerik igazán az emberek, olykor mi magunk, építészek sem. Ismereteinket folyamatosan felülvizsgálnunk és gyarapítanunk kell, hiszen a Bauhaus megítélése is változik az időben, és e megítélésnek mi is tevékeny részesei vagyunk. Konferenciánkat ezzel az igénnyel szerveztük, és a magas színvonalú előadások jelentősen bővítették tudásunkat, árnyalták, finomították, gazdagították róla alkotott képünket.
An analysis of Mandarin Chinese final particle ba in dispreferred responses
Authors: Xu Jun
Published: February 2020

In Mandarin Chinese conversation, the final particle ba is considered to perform various functions. Using conversation analysis, this article examines the use of the final particle ba in dispreferred responses. It is argued that the particle ba is used to mitigate negative valence with delays, alternative choices, accounts, and pro-forma agreement as well as other linguistic features in disagreements and declining suggestions or invitations. Also, the results reveal a close relationship between the particle ba functioning as a mitigator or displaying a speaker’s uncertainty in social actions as well as sequential positions.
Prymas Stefan Wyszyński – „antysemita”, „rasista” i „faszysta”. Historia podwójnej manipulacji tekstami z „Ateneum Kapłańskiego”
Authors: Czaczkowska Ewa K.
Published: February 2020

Informacje o rzekomym antysemityzmie, rasizmie i faszyzmie ks. Stefana Wyszyńskiego, w latach 1932–1939 redaktora naczelnego miesięcznika „Ateneum Kapłańskie”, pojawiają się co pewien czas w przestrzeni medialnej. Ostatnia fala tych informacji obiegła portale i fora internetowe w latach 2012–2014, głównie za sprawą ówczesnego polityka Janusza Palikota, który na swoim blogu napisał, że „Kardynał tysiąclecia, Wyszyński, jeszcze jako zwykły ksiądz i teolog był orędownikiem nazizmu i samego Hitlera, co znajdowało wyraz w redagowanych przez niego publikacjach”. Trzy miesiące później na forum.gazeta.pl ukazało się siedem cytatów rzekomo pochodzących z tekstów ks. Wyszyńskiego, opublikowanych w „Ateneum Kapłańskim”, a mających udowadniać tezę o jego rzekomym również antysemityzmie, rasizmie i faszyzmie. Od tego momentu informacja ta zaczęła żyć własnym życiem – powielana była na różnych forach, portalach, a także w publicznej telewizji. W listopadzie 2013 roku w programie telewizyjnym „Świat się kręci” aktor Jacek Poniedziałek oskarżył prymasa Wyszyńskiego o wypowiedzi „antysemickie” i proeugeniczne.Zastosowana manipulacja jest dwojakiego rodzaju. Cytaty (w dodatku, czasami zniekształcone) nie pochodzą z artykułów ks. Stefana Wyszyńskiego. Ich autorami byli ks. Józef Pastuszka oraz ks. Paweł Tochowicz. Lektura tekstów, w tym cytatów bez wyrywania ich z kontekstu, pokazuje, że autorzy dokonując wielorakiego rodzaju naukowych analiz rasizmu, nacjonalizmu i politycyzmu, z pozycji chrześcijańskich krytykowali poglądy Adolfa Hitlera.
Chrzest jako misterium pieczęci w tradycji pierwszych trzech wieków
Authors: Mateja Leszek
Published: February 2020

Artykuł ukazuje, w jaki sposób w pierwszych trzech wiekach rozumiano chrzest jako misterium pieczęci. Ten aspekt chrztu był już podkreślany we wspólnocie z Qumran, a także w doświadczeniu chrztu Jana Chrzciciela, o czym w I wieku pisał Józef Flawiusz. Ojcowie Kościoła w II i III wieku używają wprost sformułowania pieczęć chrztu. Autor Pasterza Hermasa reprezentujący środowisko Rzymskie oraz Klemens Aleksandryjski uważali, że chrzest w imię Ojca i Syna, i Ducha Świętego pieczętował egzystencjalne wyznanie wiary w Jezusa jako Syna Bożego. Natomiast Tertulian z Kartaginy ukazał szerzej proces wzrostu egzystencjalnej wiary w ramach procedury inicjacji przedchrzcielnej, a także jej dalszy rozwój przygotowujący chrześcijan do przyjęcia chrztu krwi, czyli męczeństwa za wiarę w Jezusa. Chrzest Janowy, czyli chrzest nawrócenia i chrzest krwi były rozumiane przez chrześcijan symbolicznie i stanowiły niejako ramę dla jedynego chrztu, przez nich przyjmowanego.
GnRH Agonist Uzun Protokol tedavi uygulanan Polikistik Over Sendromu olan ve olmayan hastaların gebelik sonuçlarının karşılaştırılması
Authors: SEYHAN Alper , SOFUOĞLU Kenan , OSMANLIOĞLU Merve Begüm
Published: February 2020

BAŞLIK:GnRH Agonist Uzun Protokol tedavi uygulanan Polikistik Over Sendromu olan ve olmayan hastaların gebelik sonuçlarının karşılaştırılmasıÖZET: Kadın infertilitesinin en sık  nedeni ovulasyon bozukluklarıdır. Anovulatuar infertilitenin en temel nedeni Polikistik Over Sendromudur. Polikistik Over Sendromu fertil çağdaki kadınlarda görülen en sık endokrin bozukluktur. Polikistik Over Sendromlu infertil kişide ilk tercih ovulasyon indüksiyon ajanı Klomifen Sitrat’tır. Klomifen Sitrat’a yanıtsız olgularda eksojen gonadotropinler kullanılmaktadır. Çalışmamızda,   GnRH Agonist Uzun Protokol uygulanan PKOS olan ve olmayan hastalarda gebelik sonuçları ve yanısıra kullanılan gonadotropin dozları, bazal FSH, E2, prolaktin değerleri, elde edilen matur oosit sayıları gibi parametreleri retrospektif olarak karşılaştırmayı hedefledik.
Motivación y satisfacción laboral del personal de Enfermería en el Hospital de Apoyo San Francisco, Ayacucho-2018
Authors: Montes Salcedo Marleny , Díaz Orihuela María Magdalena
Published: February 2020

Objetivo del estudio fue determinar la relación que existe entre el grado de motivación y el nivel de satisfacción laboral del personal de enfermería que labora en el Hospital de Apoyo San Francisco Ayacucho, 2018. Metodología: Tuvo un enfoque cuantitativo y de tipo correlacional, de diseño no experimental. El Instrumento para valorar la variable motivación fue trabajado por Hackman y Oldham (1974), y para evaluar la satisfacción laboral se usó la escala SL-SPC comprobado por la psicóloga Sonia Palma, ambos instrumentos se aplicaron a 50 personas que representan al personal de Enfermería. Resultados: Permitieron demostraron que entre la variable motivación y la variable satisfacción laboral muestran una relación moderada directa y significativa (r=0.488, p=0.000), el análisis realizado entre la variable satisfacción laboral y las dimensiones de la motivación evidenció relación moderada y significativa en la retroalimentación (r=0.425,p=0.002), y la autonomía para la realización de la tarea (r=0.406, p=0.003); la importancia de la tarea reveló relación baja directa y significativa (r=0.334, p=0.000).No se encontró suficiente evidencia para afirmar una relación entre la satisfacción laboral y las dimensiones identidad con la tarea (r=0.251, p=0.079), y variedad de la tarea (r=0.049, p=0.736). Conclusión: Que existe relación moderada entre la variable motivación y satisfacción laboral. Asimismo, se observa una relación moderada entre la dimensión retroalimentación y autonomía para la realización de la tarea
Eficacia del programa educativo “Por una sexualidad responsable” sobre los conocimientos de sexualidad en adolescentes del quinto año de secundaria de la Institución Educativa Adventista Puno, Puno, 2016
Authors: Alarcón Rodriguez Raquel , Surco Quispe Melisa , Chura Muñuico Ruth
Published: February 2020

Objetivo: Fue determinar la eficacia del programa educativo “Por una sexualidad responsable” sobre los conocimientos de sexualidad en adolescentes del quinto año de secundaria de la I. E. Adventista Puno- Puno, 2016. Metodologia: El estudio fue de tipo cuantitativo, diseño cuasi experimental, aplicando una pre y post prueba. La muestra estuvo conformada por 51 adolescentes de 14 a 17 años, distribuidos en dos grupos de manera aleatoria: grupo experimental y grupo control. Instrumento: Para medir el nivel de conocimiento se aplicó un cuestionario sobre sexualidad en adolescentes. Los resultados del “grupo control”: en el pre test un 48,1% nivel bajo y 44,4% nivel medio, en el post test se mostró un resultado similar de 48.1% en el nivel bajo y 48,1% en el nivel medio. Resultados: En el “grupo experimental” antes de la aplicación del programa el 50,0 % presentaron un nivel medio y 33,3% un nivel bajo, solo el 16,7% un nivel alto, en el post test los conocimientos de los adolescentes se incrementaron a un 83,3 % con un nivel alto y un 16,7% un nivel medio, habiendo diferencia significativa en comparación con el grupo control. Conclusión: Que a un nivel de significancia de (sig= ,000), el programa educativo fue efectiva en la mejora de conocimientos sobre sexualidad en los adolescentes.
Lipid Annotation of MALDI IMS Datasets v1
Authors: Neumann Elizabeth , Allen Jamie , Spraggins Jeff , Gutierrez Danielle
Published: February 2020

Scope: Annotate lipid species detected by MALDI IMS analysis. Expected Outcome: A list of lipid identifications with low mass errors (<5 ppm) that correlate to ion images produced by MALDI IMS analysis.
VU Biomolecular Multimodal Imaging Center (BIOMIC) kidney characterization pipeline for tissues collected through the Cooperative Human Tissue Network (CHTN) v2
Authors: Neumann Elizabeth , Allen Jamie , Brewer Maya , Anderson David , De Caestecker Mark , Gutierrez Danielle , Spraggins Jeff
Published: February 2020

We aim to develop high resolution, chemically informative imaginig methodologies for building an atlas of human organs, such as the kidney. Scope: Provide an overview of the methods used by the Vanderbilt Tissue Mapping Center as part of the Human Biomolecular Atlas Program (HuBMAP, NIH Common Fund) and contextualize individual protocols within our larger workflow.
A Degree Theory for Lagrangian Boundary Value Problems
Authors: Alsaedy Ammar , Tarkhanov Nikolai
Published: February 2020

We study those nonlinear partial differential equations which appear as Euler-Lagrange equations of variational problems. On defining weak boundary values of solutions to such equations we initiate the theory of Lagrangian boundary value problems in spaces of appropriate smoothness. We also analyse if the concept of mapping degree of current importance applies to Lagrangian problems
Transient coma as Percheron’s artery stroke
Authors: Cotelli Maria sofia , Civelli Patrizia , Tosana Elisa , Turla Marinella
Published: February 2020

The artery of Percheron is a rare anatomic variation in the brain vascularization, in which a single arterial trunk arises from the posterior cerebral artery to supply both sides of brain structures, i.e., the thalamus and midbrain. Occlusion of this uncommon vessel results in a characteristic pattern of bilateral paramedian thalamic infarcts with or without mesencephalic infarctions. We report the case of a Caucasian woman who completely recovers after transient coma due to Percheron artery infarction.
Nutritional value and inclusion levels of residual annatto seed meal in diets for Japanese quails
Authors: Pimentel-Mani Iana , Oliveira Maria C , Lima-Dóro Sarah CO , Carneiro-Martins Poliana , Souza-Júnior Marcos AP
Published: February 2020

Background: Residual annatto seed meal (RASM) is a byproduct after extraction of bixin in the cosmetic industry and may be used in animal diets. Objective: Two experiments were carried out to determine the nutritive value and effect of RASM inclusion levels in the diets of Japanese quails. Methods: For the digestibility experiment, 160 Japanese quails were distributed in a randomized study with two treatments and 10 replicates with eight birds each. The treatments consisted of a reference diet and a test diet containing 75% of the reference diet and 25% of RASM. For the performance assay, 192 Japanese quails were used in a randomized study with six treatments and four replicates with eight birds each. Treatments consisted of a control corn-based diet (Contr1) and another diet based on sorghum + canthaxanthin (Contr2), and four diets based on sorghum with increasing inclusion levels of RASM (0, 3, 6, and 9%). Results: Digestibility of dry matter and crude protein, metabolization coefficient of gross energy, and retention of calcium and phosphorus were 41.05, 43.12, 47.97, 25.49, and 30.35%, respectively. RASM inclusion did not influence bird productivity; however, feed conversion worsened in treatments with 0–6% RASM inclusion relative to that in Contr1. Yolk color increased due to RASM treatment. Conclusion: RASM may be included in sorghum-based diets for quails at 9%, with improvement in yolk color and no negative effects on productivity and egg quality.
Beef quality of Nellore steers fed dried or rehydrated and ensiled corn or sorghum grains
Authors: Ferreira Fabiano A , Chizzotti Mario L , Zamudio Germán DR , Estrada Mauricio M , Pacheco Marcos VC , Silva Breno C , Valadares-Filho Sebastião C , Rodrigues Rafael TS
Published: February 2020

Background: Rehydration of grains, such as corn and sorghum, is used to increase nutrient absorption. However, the effect of this practice on meat quality is poorly understood. Objective: To evaluate the effects of type of grain and processing on the meat quality of Nellore steers in a feedlot. Methods: Twenty-four non-castrated Nellore steers (270 ± 53 kg initial body weight) were distributed in a completely randomized 2×2 factorial design, with six replicates. The first factor was cereal type (corn or sorghum), and the second was the grain processing (dry or rehydrated and ensiled). The diets were composed of 28.44% corn silage and 71.56% concentrate. Sixty days before the beginning of the experiment, corn and sorghum grains were rehydrated and ensiled. The animals were slaughtered after 140 days of confinement. Meat quality analyses were determined in samples of fresh and aged meat (7 days) from the Longissimus lumborum muscle. Results: no difference between treatments was observed for carcass pH and L* (lightness), a* (redness), and b* (yellowness) values, shear force, thawing and cooking losses, and chemical composition of meat (p>0.05). The b* (yellowness) value of subcutaneous fat was higher in steers fed corn, regardless of grain processing (p=0.03). Sarcomere length was higher in aged meat of steers fed sorghum, regardless of processing method (p=0.01). Conclusions: the grain processing method does not affect beef quality; however, grain type can affect subcutaneous fat color and sarcomere length of aged beef.
Means and methods of formation of organizational and managerial competence of a university teacher
Authors: Solovova Natalya V. , Sukhankina Natallia V.
Published: February 2020

The article reports the findings of the pilot research that investigates the development and testing of a system of tools and methods employed for formation of organizational and managerial competence of a university teacher. The tool for organizational and managerial competence formation analyzed herein is the additional professional program, i.e. “Educational Programs Management”, implemented at the Center for the Development of Professional Competencies of Samara University. The program is aimed at the development of organizational and managerial competence components (value-motivational, cognitive, design, expert), formation of students' readiness for effective interaction in the course of design and implementation of competitive educational programs. Educational Programs Management includes four sections: Economics of education: analysis and control of the financial and economic activities of higher educational organizations; Educational program management; Economics of educational program; The quality and competitiveness of the educational program. The content of sections and subsections of the program, training methods, ensuring the development of indicators of value-motivational, cognitive, design and expert components, were selected with due respect to the structure of the organizational and managerial competence being formed. It has been revealed that it is reasonable to use the methods as follows: ways of positive motivation formation (productive learning environment; diversity and inclusion; professional and personal achievements and accomplishments, etc.); interactive teaching methods (role-playing and business games, discussions, brainstorming, case studies, trainings, etc.); methods for the development of personal educational environment (the use of personal experience of teachers, self-reflection, self-knowledge, etc.). The research has confirmed the efficiency of the developed system of tools and methods under study, which has been developed for formation of organizational and managerial competence of university teachers based on the growth of the self-esteem index of its components and changes in the dominant indicators.
Isolation and characterization of the mutant N-terminal catalytical module of the B. taurus Tyrosyl-tRNA synthetase with the replacement of Trp87 and Trp283 by alanine
Authors: Tsuvarev O. , Kolomiiets L. , Zayets V. , Blaszczak I. , Kornelyuk A.
Published: February 2020

Aminoacyl-tRNA synthetase is one of the major enzymes of protein synthesis. The mammalian tyrosyl-tRNA synthetase consists of two structural units, the N-terminal catalytic (mini TyrRS) and the C-terminal cytokine-like modules. In a full length TyrRS, the N-terminal module carries out the catalytic function of binding the amino acid to tRNA, while the C-module adjusts and stabilizes the placement of tRNA in the active center of the enzyme. After cleavage of tyrosyl-tRNA synthetase with elastase on the mini TyrRS and C-module, the latter exhibit cytokine properties. The aim of the work was to optimize the expression of cloned cDNA miniTyrRS Bos taurus in plasmid pET30a-39KYRS in which the tryptophan codons at position 87 and 283 are replaced with alanine codons using the site-directed mutagenesis, and to obtain the mutant one-tryptophan protein of the mini BtTyrRS for further study on using methods of fluorescence spectroscopy of conformational changes of the enzyme at the stage of tyrosyladenylate formation and in interaction with the acceptor end of tRNATyr, as well as determination of the effect of tryptophan residus in positions 87 and 283 in its structure on the structurally dynamic and functional properties of the enzyme.
It was found that the replacement of two tryptophan codons into the alanine codons in the cDNA of the mini TyrRS cloned in the expressing plasmid pET30a-39KYRSW40 does not affect the synthesis and solubility of the mutant form of the enzyme in the strain E.coli BL21 (DE3) pLysE. The amount of soluble form of the recombinant mutant mini BtTyrRS in the cytoplasm of bacterial cells, when expressed in E. coli BL21 (DE3) pLysE strain, is significantly enhanced by incubation of bacterial culture at a temperature 25 ° C compared to a culture incubation at 37° C. The yield of the obtained purified protein of the mutant mini BtTyrRS is 2.5 mg per average from 100 ml of culture medium, which is sufficient for further structural and functional studies of the mutant form of the enzyme. The compact structure of the recombinant protein is shown by fluorescence spectroscopy.
THE PHENOMENON OF BIOPOLITICS: STATUS AND PROSPECTS
Authors: Kyselov Mykola
Published: February 2020

Analyzed heuristic possibilities, limits of competence and subject field of biopolitics study are an important fragment of a new complex scientific direction of biophilosophy. The position about its socio-natural character is argued: the integration of biology with the sciences of man and society. The reasons for the actualization of the problems of biopolitics and biopower under the current conditions (the market economy crisis, ecological and anthropological crisis, the progress of global warming) are considered.
It is shown that the planetary issues of migration, rise in inequality and the New Climate Regime are actively involved in the field of biopolitics. The skepticism about expectations for globalization, that is already perceived as «provincial vision, proposed by a few individuals, representing a very small number of interests», that «has been imposed on everyone and spread everyone». (B. Latour). It is emphasized that ecology has made efforts to attract attention to the global problems of humanity and created an «environmental dimension» in everything, including politicum, and yet it has not lived up to the expectations: Greens Parties remain dependent everywhere on the minorities seeking support. It is at the level of biopolitics, one has to be understood that the inaccuracy of the classic contrast the environment with the organism, nature with man and human nature with culture.
It is concluded that biopolitics has to play a pivot role in the decision of the global «survival strategy» and the preservation of life on the planet. It must find support and resilience in a situation of unprecedented destruction of all living things.
THE ACQUISITION OF FOREIGN LANGUAGE BY STUDENTS WITH INTELLECTUAL DISABILITY IN AN ELEMENTARY SCHOOL
Authors: Poļaka Anna
Published: February 2020

The aim of the research: to investigate development opportunities of the acquisition English by the students with intellectual disability of class 6 and 9 and to analyze results of research and work out conclusions. It was analyzed information from literature sources about the organization of the learning process for students with intellectual disability and the feature of teaching English to students with intellectual disability in the theoretical part of the research. The empirical part of this paper was conducted during a year (from May 2018 to May 2019). The participants in this study are nine males and females with mild retardation.
EXPERT INTERVIEW ANALYSIS WITHIN THE STATE EMPLOYMENT AGENCY’S MEASURE “MOTIVATION PROGRAM FOR JOB SEEKING AND SOCIAL MENTOR SERVICES”
Authors: Zahare Astrīda
Published: February 2020

Currently long-term unemployment is a significant problem in Latvian labour market, therefore a topical issue is the integration of the long-term unemployed into the labour market, as well as low motivation of the target population.From December 2015 till 31 December 2021 an ESF project “Support for the Long-term Unemployed” is being implemented, this project includes the implementation of a measure “Motivation Program for Job Seeking and Social Mentor Services” which aims to motivate and to preventively support the long-term unemployed, as well as to facilitate their placement in appropriate permanent workplaces.Aim of the expert interviews was to find out whether the motivation of the long-term unemployed was changed during the State Employment Agency’s measure “Motivation Program for Job Seeking and Social Mentor Services”, and in case of affirmative result to observe what were these changes. In addition, the data from expert interviews were compared with the data from the questionnaires that were completed by the participants in the measure.
THE USE OF THE MULTISENSORY METHOD NUMICON IN LEARNING BASIC MATHEMATICAL SKILLS BY STUDENTS WITH MODERATE MENTAL DISABILITIES
Authors: Krauce Antra
Published: February 2020

The article “The use of the multisensory method Numicon in learning basic mathematical skills by students with moderate mental disabilities” briefly analyses basic math learning skills of the student with moderate mental disabilities and gather the teaching methods that can be used by teachers. The multisensory method Numicon is described in detail how it can be used in work with the students with moderate mental disabilities. The description of the author’s methodological material “Mathematics with Numicon” is also provided. The results of the research are summarized about the basic mathematical skills for the students with moderate mental disabilities by using the multisensory method and the Numicon materials, and authors methodological material  “Mathematics with Numicon”.
CYBER-MOBBING IN SCHOOL: MITIGATION OPTIONS
Authors: Orska Rita
Published: February 2020

Relationship building is always a complicated process. Pupils develop this skill by trial and error, experiencing conflicts, the escalation of which is rapid and high. By reaching the stage when the other conflict party becomes an enemy, inadequate actions take place. One of such actions is mobbing, while using the latest information technologies it becomes cyber-mobbing. Cyber-mobbing is hidden mobbing. Its aim is to cause the most harm to the victim without being caught and/or punished for such an action. Informative efforts on cyber-mobbing, its harm, detection possibilities, both in schools and in the society in general (mass media) are being made, yet it is only one of the preventive work forms. In order for preventive work on mitigation of cyber-mobbing to become more efficient, more diverse preventive work forms and methods shall be used. Currently, animation and mediation methods are applied in worldwide pedagogical practice. The use of such methods shows significant positive results in mitigation of cyber-mobbing.
ASSESSMENT OF HUMORAL IMMUNITY IN PATIENTS WITH CHRONIC VIRAL HEPATITIS B, COMBINED WITH CHRONIC NON-CALCULOUS CHOLECYSTITIS
Authors: Yakimovich S E
Published: February 2020

The article presents data on assessing the state of the humoral immunity in patients with chronic viral hepatitis B, combined with chronic non-calculous cholecystitis, as chronic liver viral lesions are immune-mediated condition, depending on the replicative activity of the virus and the immune system’s responses to this virus. At the same time, there is an increase in the overall level of CIC in serum and an imbalance in the molecular composition of immune complexes, as well as a decrease in the immunological reactivity in such patients.
FEATURES OF FUNCTIONING OF THE IMMUNE SYSTEM UNDER STRESS
Authors: Zaitseva N S , Syziakina L P
Published: February 2020

The psychobiological essence of stress is to reprogram the resources of the human body for survival in extreme life-threatening conditions. The study of the activity of the main homeostatic systems in acute and prolonged adaptive reactions in soldiers is of great scientific and practical interest. The immune status was assessed in 42 military officers who participated in special operations for the first time. Not only quantitative, but also structural changes of the immune system function in the military-participants of special operations were revealed. The results require further analysis, study and consideration in assessing the health of soldiers.
The relevance of cytokine indicators in the hemorrhagic transformation development of cerebral infarction risk measuring
Authors: Nikiforova T A , Doronin B M , Peskov S A
Published: February 2020

The purpose of this research is to study the prognostic role of cytokines in plasma in patients with cerebral infarction while assessing the risk of hemorrhagic transformation.Materials and methods. Three groups of patients were identified. Group 1: 66 patients with cerebral infarction without hemorrhagic transformation (CI without HT), mean age 63.9 ± 1.3 years. Group 2: 27 patients with cerebral infarction and with hemorrhagic transformation (CI with HT), mean age was 65.9 ± 2.5 years. Group 3: 65 patients with cerebral hemorrhage (CH), average age - 58.8 ± 1.6 years. The plasma cytokines concentration measurement (IL-1β, TNF-α, IL-6, IL-8, IFN-γ, IL-1Ra, IL-10, IL-4) was performed on the 1st, 2nd and 10th days after the stroke manifestation. The control group - 55 donors cytokines indicators.Results. In the CI with HT group, compared with the CI without HT group and the CH group, the lowest levels of IL-1β and TNF-α were detected on the 1st, 2nd and 10th day since the disease symptoms, and, conversely, the highest IL-1Pa values were revealed on the 1st and 2nd days; IL-4 values - on the 1st and 10th days (p < 0.05). The high HT development risk factors on the 1st day of the disease symptoms are IL-6 ≥ 46.6 pg/ml, IL-8 ≥ 14.7 pg/ml, IL-10 ≥ 12.1 pg/ml, IL-4 ≥ 7.6 pg/ml. In contrast, IL-1β ≥ 1.9 pg/ml, TNF-α ≥ 14.4 pg/ml indicate a low probability of HT development.Conclusion. Predictors of the CI HT development risk on the 1st day of the disease are plasma cytokines indicators IL-1β, TNF-α, IL-6, IL-8, IL-10, IL-4.
COMPARATIVE EFFECT OF KE AND EW PEPTIDES ON NORMAL AND TUMOR IMMUNE CELLS
Authors: Linkova N S , Mironova E S , Ivko O M , Orlova O A , Dudkov A V
Published: February 2020

KE and EW peptides have an immunoprotective and oncostatic effect in experimental studies. However, their comparative effect on normal and cancer immune cells has not been carried out yet. The aim of the work is to study the effect of KE and EW peptides on T-lymphocytes and Berkitt lymphoma cells growth in culture. To plot the cell growth curve, the cells were scattered at a concentration of 20,000 per 2 ml. KE and EW peptides were added to cultures at 100 ng/ml. Counting cells was carried out in the Gorjaev’s chamber. KE and EW peptides increased the number of lymphocytes of human blood as compared with the control during 5 days by 64-219%. KE and EW peptides reduced the number of Burkitt lymphoma cells as compared with the control during 5 days by 37-101%. KE and EW peptides decreased tumor immune cell proliferation and increased normal human lymphocytes grow. We suppose, that these effects can be connected with various ways of peptide regulation of methylation status of DNA.
PREDICTORS OF EFFECTIVE USE OF T CELL MIMETICS IN IMMUNE AND ENDOCRINE DISORDERS TREATMENT
Authors: Luybimov D S , Britanov A N
Published: February 2020

98 infants with acute bronchitis aged 3-36 months showed general basic adaptive response on the acute stage: depression of cellular immune response, active humoral immune response, CIC increase and enhanced phagocytic capacity of neutrophils. ACTH and TSH levels were elevated against depletion of cortisol and triiodothyronine levels. Clinical markers together with immune and endocrine predictive markers of the disease severity, character of complications and comorbidity were revealed. Thymogen is indicated for treatment in case of prevailing of hyperergic disorders both in the central core of neurohumoral regulation and the intra-immune - IgA increase. Thymaline proves effective in hyperergia treatment - thymomegaly with low IgA and cortisol levels along with pre-existing bacterial infections.
CALPAIN ACTIVITY UNDER EXPERIMENTAL INCREASING OF DOPAMINE LEVEL
Authors: Pestereva N S , Marshak A Z , Karpenko M N
Published: February 2020

The aim of our study was to identify the activity of calpains under conditions of an experimental increase in the level of dopamine. The work was performed at three levels: in vivo, in situ, in vitro. An in situ study was carried on a model of isolated nerve endings - synaptosomes. Using casein zymography in solution with FITC-casein, it was shown that incubation of synaptosomes dopamine leads to calpains secretion into the synaptosomal medium. The dopamine ability to directly activate calpain was demonstrated by casein zymography in a gel. Incubation in an activation buffer containing dopamine instead of the classical activator, calcium chloride, led to the activation of calpain-2. An in vivo experiment was performed on Wistar rats. The experimental group was orally administered the drug L-dopa (100 mg/kg), the control group - saline was injected in the same way.
THE DEVELOPMENT OF NEUROINFLAMMATORY PROCESSES IN RATS IN EARLY POSTNATAL ONTOGENESIS AFTER PRENATAL HYPERHOMOCYSTEINEMIA
Authors: Shcherbitskaia A D , Vasilev D S , Tumanova N L , Milyutina Ju P , Zalozniaia I V , Arutjunyan A V
Published: February 2020

Prenatal exposure to high levels of homocysteine has long-term impact on growth retardation of nervous system development and is related to central nervous system diseases in children. However, it is not well-characterized whether gestational exposure to hyperhomocysteinemia (HHC) affects the development of nervous system in offspring. It was observed disturbed neuroblast generation and migration, neuronal death in cortex, revealed as reduction of pyramidal neurons number, and activation of glia in the month after birth in offspring subjected to HHC. These disorders may be associated with changes in the content of pro-inflammatory cytokines in the cortex tissue of HHC pups.
THE LEVEL OF SYSTEMIC INFLAMMATION AND CHANGES IN ADAPTIVE IMMUNITY IN ALCOHOLIC PSYCHOSES
Authors: Didkovsky N A , Malashenkova I K , Ogurtsov D P , Krynskiy S A , Hailov N A , Chekulaeva E I , Mamoshina M V , Ushakov V L , Zakharova N V , Kostyuk G P
Published: February 2020

The aim of the work is to study the level of systemic inflammation and changes in adaptive immunity in the early period after acute psychosis to assess their participation in the pathogenesis of alcoholic mental and cognitive disorders. We examined 28 patients with alcoholic psychosis (AP) and a control group of 17 healthy volunteers. Indicators of systemic inflammation and immunity, including key cytokines and lymphocyte subpopulations, were investigated. After acute psychosis of patients with alcoholism, pronounced activation of humoral immunity with impaired clearance of immune complexes, increased content and activity of Th2 with signs of insufficiency and dysfunction of Th1, reduced content and activity of cytotoxicity system cells and signs of systemic inflammation (increased CRP, cortisol, cytokines). Activation of Th2 response and an excess of proinflammatory mediators in patients with AP through various ways of interaction with the Central nervous system (n. vagus, choroidal plexus of the ventricles, and others) can participate in the disorders of metabolism of neurotransmitters in the Central nervous system involved in the pathogenesis of alcoholism, and in the maintenance of neuroinflammation. A high level of systemic inflammation can be both a trigger of psychosis and a manifestation of violations of neuroimmune interactions, as well as the development of excitotoxicity and damage to neurons in acute psychosis.
HUBUNGAN ANTARA PERILAKU MEROKOK PADA ORANG TUA DENGAN KEJADIAN INFEKSI SALURAN PERNAPASAN ATAS (ISPA) PADA ANAK SEKOLAH DASAR USIA 7-12 TAHUN DI PUSKESMAS PORONG
Authors: Rachmawati Aisyah , Winarno M.E. , Katmawanti Septa
Published: February 2020

Abstract: Smoking is an unhealthy behavior that has been common thing in the society. In 2013, noted that the smoker reach 36.3% in number while smoking cause respiration problems, one of it is respiration problem. In 2013, East Java became one of province with highest ISPA case. This study as a purpose to find the relationship between smoking behavior in the parents with the incidence of ISPA in elementary children in Porong Primary Health Care with the working hypothesis is there is a significant relationship between variables. This research uses correlational quantitative research design with 115 samples. Data analysis is using Spearman Rank test. The sampling technique used is Purposive Sampling. Technique of collecting data is using questionnaire. Instrument used to collect data in the form of human instruments, namely researchers herself. Data analysis activities started from the preparation stage, data collection, data entry, data analysis, and hypothetical test.The result of research based on item score found there is significant correlation in result of hypothesis test with P value (0.00) < α (0.05) with correlation coefficient (r) obtained is 0.588. Keywords: Smoking Behavior, Upper Respiratory Infection, Porong Primary Health CareAbstrak: Merokok adalah perilaku tidak sehat yang telah dianggap biasa oleh masyarakat. Pada tahun 2013 tercatat bahwa jumlah perokok mencapai 36,3% sedangkan, merokok menyebabkan berbagai permasalahan kesehatan, salah satunya adalah masalah pernapasan. Pada tahun 2013, Jawa Timur menjadi salah satu provinsi dengan ISPA tertinggi. Penelitian ini dilaksanakan dengan tujuan untuk mencari hubungan antara perilaku merokok pada orang tua dengan kejadian ISPA pada anak sekolah dasar di Puskesmas Porong dengan hipotesis kerja adalah ada hubungan yang signifikan antar variabel. Rancangan penelitian ini adalah kuantitatif korelasional dengan sampel sebanyak 115 orang. Analisis data menggunakan uji Spearman Rank Test. Teknik pengambilan sampel yang digunakan adalah Purposive Sampling. Teknik pengumpulan data menggunakan metode kuesioner. Instrumen yang digunakan untuk mengumpulkan data berupa instrumen manusia, yaitu peneliti sendiri. Kegiatan analisis data dimulai dari tahap persiapan, pengambilan data, entry data, analisis data, dan pengujian hipotesis. Hasil penelitian berdasarkan nilai skor butir pertanyaan didapatkan ada hubungan yang signifikan dalam hasil uji hipotesis dengan nilai P (0,00) < α (0,05) dengan koefisien korelasi (r) yang didapatkan adalah 0,588.Kata kunci: Perilaku Merokok, Infeksi Saluran Pernapasan Atas, Puskesmas Porong
ANALISIS RISIKO BAHAYA PADA PEKERJA DI TEMPAT PENAMPUNGAN SAMPAH TERPADU REDUCE REUSE RECYCLE (TPST 3R) MULYOAGUNG BERSATU DAU KABUPATEN MALANG
Authors: Alma Lucky Radita , Ulfah Nurnaningsih Herya , Utomo Yudhi , Afifah Afifah , Adawiyah Uciatul , Kholifah Wakhi Datul Nur , Merillarosa Iing
Published: February 2020

Tempat penampungan sampah terpadu reduce reuse recycle (TPST 3R) Mulyoagung Bersatu Dau merupakan salah satu diantara TPS yang ada di Kabupaten Malang. Setiap harinya TPS tersebut menampung berbagai macam sampah dari masyarakat di sekitar Kecamatan Dau sebelum diangkut ke TPA. Kegiatan pengelolaan sampah yang dilakukan pekeja, pengumpulan dan pemilahan sampah, mempunyai potensi terjadinya kecelakaan dan penyakit akibat kerja terlebih pelaksanaan K3 belum dilakukan sesuai standar. Tujuan penelitian ini untuk mengetahui gambaran risiko bahaya pada pekerja di TPST 3R Mulyoagung Bersatu Kecamatan Dau Kabupaten Malang. Penelitian ini merupakan penelitian diskriptif observasiional. Responden penelitian sebanyak 36 orang. Hasil dari penelitian ini, sebanyak 58% pekerja menyatakan bahaya yang “Sering” terjadi pada pekerja adalah tergores dan terjatuh. Sebesar 58% pekerja menyatakan “Sering” mengalami diare dan gangguan gastroinstestinal. Diperlukan upaya pencegahan dan penanggulangan terhadap bahaya ditempat kerja misalkan dengan praktik kerja yang aman, penggunaan Alat Pelindung Diri (APD) yang sesuai standart dan praktik higiene perorangan untuk mencegah terjadinya penularan penyakit bawaan sampah.
Overexpression of Cytochrome P450 CYP6CM1 Gene in Bemisia tabaci (Gennadius) in the Cotton Fields of the Çukurova Region, Turkey
Authors: ULUSOY Selçuk
Published: February 2020

In Cukurova region, neonicotinoid group
insecticides are widely used in cotton cultivation areas for controlling B. tabaci; as a result of this use,
there is a problem of resistance in these areas. In this study, cytochrome P450
CYP6CM1 relative expression levels, which are the indicators of imidacloprid
resistance, were analyzed. Five different B.
tabaci populations were collected from Adana city cotton cultivation areas
in 2018 and the indicators were observed. On the other hand, GST gene relative
expression profile, which is an efficient factor in metabolic resistance,
cytochrome P450, carboxylesterase (AcHE) and Glutathion S transferase (GST)
enzyme activities were determined. The highest cyp6cm1 and GST genes relative
activities were determined in Meletmez population; the activity level was 18, 2
and 9 times higher than susceptible population. On the other hand, the highest
and lowest cytochrome P450 enzyme activity was observed in Meletmez and Solaklı
populations, respectively. According to the analyses, it can be concluded that
there is extensive imidacloprid and neonicotinoid resistance of B. tabaci
populations in Çukurova Region cotton cultivation areas. As a result, excessive
gene expression and high-level enzyme activities indicate that there is a
resistance in the studied area based on enforced monooxygenases activity.
Arazi Toplulaştırma Projelerinin Tarımsal Mekanizasyon İşletmeciliğine Etkisi
Authors: KUZU Hamza , DEĞİRMENCİ Hasan
Published: February 2020

Bu
araştırma; arazi toplulaştırma projelerinin tarımsal mekanizasyon
işletmeciliğine etkisini belirlemek amacıyla Niğde İli Misli Ovasında
gerçekleştirilen Aşlama, Çarıklı, Çayırlı, Karaatlı Köyü arazi toplulaştırma
(AT) projelerinde yürütülmüştür. Basit tesadüfi örnekleme yöntemine göre
seçilen 96 işletmeye ait parsellerin AT öncesi ve sonrası Alan Yol Uzunluğu
Uygunluğu (AYU), Alan Kuş Uçuşu Yol Uzunluğu Uygunluğu (KUYUU), yakıt tüketimi,
parsel işleme süresi, parsel başı dönüş kaybı, yol zaman kaybı ve parsel sınır
alan kaybı parametreleri hesaplanmıştır. Çalışmada NetCAD programı
kullanılmıştır. Seçilen işletmelerde AT öncesine göre AYU ve KUYUU değerleri
sırasıyla ortalama %43 ve %37 azalmıştır. Yol uzunlukları kısaldığından yakıt
tüketimi ortalama %50, toplam üretim süresi %36 azalmıştır. AT sonrası parsel
sınır alan kaybı ortalama %38, parsel başı dönüş kaybı %38, parsellere ulaşımda
geçen süre %50, parsel işleme süresi %5 düşmüştür. İstatistiksel olarak AT
öncesi ve sonrası farklar önemli bulunmuştur (P<0.05).
Alteraciones del lenguaje oral en niños institucionalizados en hogares comunitarios: prevalencia y determinantes
Authors: Rojas Lina Marcela , Muñoz Sotelo Diego , Burbano Lasso Eimy Johana , Pacheco Robinson
Published: February 2020

Introducción: La alteración del lenguaje puede ocasionar bajo rendimiento académico y posible deserción escolar, especialmente en niños de familias desfavorecidas social y educativamente.Objetivo: Determinar la prevalencia y describir los determinantes asociados a las alteraciones del lenguaje oral en niños de hogares comunitarios (HC) atendidos por el Instituto Colombiano de Bienestar Familiar (ICBF) de la ciudad de Popayán.Métodos: Estudio observacional descriptivo de corte transversal. Incluyó 261 niños de 3-5 años de los HC. Se utilizó el test TECAL y TEPROSIF-R para evaluar el lenguaje de los menores y una encuesta sociodemográfica. Para cuantificar el grado de asociación se calculó el OR, y un análisis multivariado y el método stepwise hacia atrás para la selección de variables.Resultados: El 54.7% de los niños fueron de sexo masculino, el 55.2% entraron al jardín en el rango de 24-35 meses y el 20.3% hacían parte de una familia víctima del conflicto armado. La frecuencia de alteraciones del lenguaje oral fue 46.4%. La alteración mixta fue la más común (18.4%), luego la alteración del nivel expresivo (15.3%).  Las variables ocupación del padre (ORa: 2.35) y ser víctima del conflicto armado (ORa: 1.86) posiblemente explican de manera independiente las alteraciones del lenguaje en los niños que asisten a los HC del ICBF.Conclusiones: La prevalencia de las alteraciones del lenguaje oral en los niños que asisten a los HC es alta, se sugieren dos variables sociales con asociación: la ocupación del padre y ser víctima del conflicto armado.
Retrospective Evaluation of Elderly and Young Patients with Acute Pancreatitis
Authors: Polat Hatice Beyazal , Ayaz Teslime , Duru Hüseyin , Akdoğan Adnan Remzi , Beyazal Mehmet , Rakıcı Halil , Turan Arzu
Published: February 2020

Background/aim: Acute pancreatitis (AP) is a clinical situation that should be included in the differential diagnosis of patients presenting with complaints of abdominal pain, nausea, and vomiting. The aim of this study is to investigate the in-hospital morbidity and mortality of patients with acute pancreatitis at our clinic.

Materials and Methods: In total, 159 patients with acute pancreatitis were included in the study and analyzed retrospectively. Patients were divided into two groups: those over 65 years old and those younger than 65 years. The demographic characteristics, severity, treatment, patient prognoses,and hospitalization duration were recorded. The relationship between APseverity, etiological factors, age, gender, length of stay, and prognosis was investigated for both groups.

Results: Acute biliary pancreatitis was detected in 99 (62.3) of the 159 patients. Biliary causes were significantly higher among the elderly group. There was no relationship between disease severity and demographic characteristics or clinical and laboratory findings.

When the hospitalization period was compared between age groups, the hospitalization period for the group over 65 years was found to be significantly longer than that of the other group. The mortality rate was 0% in the group younger than 65 years and 3.2% in the group older than 65 years (three patients). This rate was not statistically significant due to the low incidence of death.

Conclusion: Gallstonesis a leading cause in the etiology of AP. Prognostic scoring systems should be used to determine the disease severity and age should be considered an additional risk factor in the increased morbidity and mortality of AP.
A comparative study to assess Nerve Conduction Velocity (NCV) test among agricultural workers who sprayed pesticide and non- agriculture workers in Wardha District in Central India
Authors: Prasad Dr. Manish A. , Peshane Dr. Rakesh , Quazi Dr. S.Z. , Mudey Dr. Abhay
Published: February 2020

Background: Pesticides are very harmful for human health especially for farmers who are more in contact with them.

Objective: To compare Nerve Conduction Test among agricultural workers exposed to pesticide and non-agricultural workers.

Method: A sample size of 83 in each group was selected. A pretested questionnaire was prepared comprising of socio-demographic profile, work practices followed by agricultural pesticide sprayers, detail clinical history & findings of Nerve Conduction Test.

Result: The mean Latency in occasional pesticide sprayer was 3.12 ± 0.95 and in regular pesticide sprayer was 3.88 ± 1.08, on applying student t test the result was observed to be significant. The mean conduction velocity in occasional pesticide sprayer was 52.95 ± 11.28 and regular pesticide sprayer was 43.96 ± 12.34, on applying student t test the result was significant.

 Conclusion: agricultural workers, pesticide sprayers, nerve conduction test, occupational health

 Keywords: Pesticide, agriculture workers, Nerve Conduction Velocity (NCV) test, Personal Protective Equipments (PPE).