bluuebunny/crossref_metadata_2025 huggingface dataset:
OPEN PUBLIC SPACES OF KYIV IN THE CONTEXT OF SOCIO-SPATIAL APPROACH
Authors: MEZENTSEVA Natalia , PALCHUK Maria
Published: March 2019

Urban public spaces determine the identity of the city’s dwellers, ensure the implementation of the communication function. They are constantly changing, characterized by various transformational processes that take place under the influence of various factors in the development of the city. The need for knowledge of contemporary complex and ambiguous processes in cities causes the relevance of the socio-spatial approach to the analysis of the functioning and transformation of public spaces in order to increase the level of comfort of living in cities, and smart management of urban development. In this aspect, Kyiv is a good ground for socio-geographical study of various types of public spaces characterized by intensive traditional and specific transformations. The most significant changes are typical for open public spaces. Therefore, in order to understand the factors of contemporary processes in open public spaces, it is necessary to carry out a socio-spatial analysis of a set of parks, public gardens, boulevards, streets, embankments and squares of the capital. The article presents results of analysis of the peculiarities of Kyiv’s open public spaces functioning and transformation in the context of the socio-spatial approach. The analysis revealed that the network of open public spaces in Kyiv corresponds to the stages of the city’s territorial development. The most widespread directions of open public spaces transformation in Kyiv are commercialization (functioning of objects providing paid cultural and entertainment services), “beautification” (club design, sculpture installation, renovation of street furniture, registration of thematic zones), (home-type behavior of visitors, the use of home decor items), “europeanization” (designing public spaces based on European urban practices), “ideologization”(commemorative practices through giving relevant names to public spaces and/or establishment of monuments), sacralization (restoration or new construction of temples in parks, squares and gardens), orientation towards the potential consumer (differences in planning design and functions depending on location in the urban planning structure) and “elitization” (allocation of facilities with the club effect). These processes make substantial impact on the intensity of the use of open public spaces in different planning zones, changing their functions and prospects of use.
KENDİNİ TANIMA, KENDİNİ GERÇEKLEŞTİRME, KENDİNİ AŞMIŞLIK, POTANSİYELİN TAM KULLANAN KİŞİ: KİŞİLERARASI İLETİŞİM
Authors: Tekke Mustafa , Çoşkun Merve
Published: March 2019

Bu araştırmada, eğitim, psikolojik ve rehberlik hizmetleri
kapsamında bireyin kendini tanıma, kendini gerçekleştirme, kendini aşmışlık ve
potansiyelini tam kullanan kişi düzeyi etraflıca tartışılmaktadır. Bunu
yaparken de kişiler arası iletişimin bahsedilen düzeylerle bağıntısı
irdelenmiştir. Bireyin kendini tanıması temel alınması Maslow’un ihtiyaçlar
hiyerarşisinin üst düzey ihtiyaçları olarak kabul edilen kendini gerçekleştirme
ve kendini aşmışlıkla ilişkilendirilmiştir. Bu, Rogers’in dile getirdiği potansiyelini
tam kullanan kişi özellikleri Maslow’un üst düzey ihtiyaçları ile
örtüşmektedir. Üst düzey ihtiyaçları gerçekleştiren bireylerin kişilerarası
iletişimleri olumlu yönde geliştiği belirlenmiştir. Bu bağlamda, oluşturulan
modelin içerdiği kendini tanıma, kendini gerçekleştirme, kendini aşmışlık ve
potansiyelini tam kullanan kişi gibi faktörler alan yazında ilk çalışma
özelliği taşımaktadır. Bu öne sürülen çalışmanın özellikle eğitimciler,
psikologlar ve rehber uzmanları, bireylerin özellikle kişiler arası iletişimde
etkileşimini anlamada yardımcı olacağı düşünülmektedir. Oluşturulan bu modelin
güvenirlik ve geçerliliğini artırma adına bir sonraki çalışmalarda yapısal
eşitlik modeli çalışmalarına yer verilmesinde fayda bulunmaktadır.
AHİLİK İLKE VE UYGULAMALARININ GÜNÜMÜZ KOBİ’LERİNE YANSIMASI: ELAZIĞ İLİ ÖRNEĞİ
Authors: Düşükcan Muhammet , Başdaş Oğuzhan
Published: March 2019

Ahilik, temelleri fütüvvet anlayışı
üzerine kurulmuş, ilkeleri insani ahlak değerleriyle oluşturulmuş sosyal,
ekonomik, siyasi ve kültürel fonksiyonları bulunan bir esnaf
teşkilatlanmasıdır. Ahilik teşkilatıyla Anadolu
insanının eğitimli ve ahlaklı birer sanatkâr olmaları sağlanmıştır. Ahi Evran
tarafından kurulan ahilik kurumu günümüzde dahi eşine rastlanılmayan muazzam
bir sistemle,  ahiliğe bağlı üyelere
mesleki eğitim vermenin yanı sıra sosyal yardımlaşma fonksiyonu da yerine
getirmekteydi. Ahilik teşkilatı Türk toplumuna mal
edilmiş, ilkeleri ahlaki değerler üzerine kurulmuş bir sistem olmakla birlikte
milli birlik ve beraberlik ülküsüyle işleyen devasa bir mekanizma örneğidir. Bu
kurum esnaf teşkilatı olarak üyelerine gerekli eğitimler vererek üretilen malın
miktarındansa kalitesine odaklanan bir anlayışa sahiptir. Girişim ve girişimcilik kavramı, son
dönemlerde büyük bir hızla küreselleşmeye sahne olan dünyada ekonomik
kalkınmanın en önemli faktörlerinden biridir. Özellikle kapitalizmin
ekonomilere egemen olmasıyla ekonomi döngüsünün çarkı görevini üstlenen
girişimciler olmadıkça ekonomik sistemin bir gelişme göstermesi mümkün
değildir. Girişimcilik bir süreçtir, pazardaki
fırsatların belirlenmesi ile başlayan, kaynak ve girdiler kullanılarak yeni
işlerin yaratıldığı, yeni ekonomik fırsatları kazanca dönüştüren dinamik bir
süreçtir. Günümüzde girişimcilik faaliyetleri
kurumsal bir çerçevede küçük ve büyük işletmelerde yapılmaktadır. Ahilikteki
esnafların günümüzdeki karşılığı olan girişimciler faaliyetlerini KOBİ’ler
vasıtasıyla yerine getirmektedir.
The Yoga of Healing: Exploring Yoga's Holistic Model for Health and Well-being
Authors: Desikachar Kausthub , Bragdon Liz , Bossart Chase
Published: March 2019

This article provides an introductory outline of the theoretical foundations for the therapeutic application of Yoga. Over the course of its several thousand year history,Yoga has evolved and refined highly effective models and tools for healing and health, many of which are discussed in the article. These models and tools are interconnected and interdependent, each one supporting the other while at the same time addressing specific aspects of the whole human system.

The article also emphasizes Yoga's holistic view of the student/patient. Yoga addresses every aspect of the human system, including the body, the mind, emotions,breathing patterns, relationships, etc. The article shows how Yoga's particular methodology enables the educated and skilled Yoga teacher to design practices tailored to respect the individuality of each person and situation.
Formación posgradual en investigación y profesión docente
Authors: Barrios Martínez Darcy Milena , Herrera González José Darío
Published: March 2019

The aim of this paper is to report on the project “The place of research within postgraduate training for DC teachers” that took place in 2014, in Bogotá (Colombia). The project focused on the perceptions teachers who benefited from the 894 project run by the Education Secretariat had regarding the link between research training, educational practice, and the teaching profession. This research was based on a hermeneutic approach and used both qualitative and quantitative research techniques that made the exploration of notions and purposes of research within postgraduate programs possible. Methods and strategies used in research training, as well as its link with educational practice and the contexts teachers taking the courses came from, were also the subject of analysis. Findings are nothing but thought-provoking given the current discussion on research training in postgraduate programs for teachers. The fact is that there is widespread interest in changing educational practice for the better, and contributing to teachers´ professional development, meeting the need to reflect on pedagogical expertise (know-how), the characteristics of each discipline and, to a lesser extent, contextual factors. These and other research findings provide a basis to establish relationships between the interests of public policy, universities, schools, and teachers undergoing postgraduate training.
Educación asesina: Percepciones de estudiantes respecto al anime Assassination Classroom y su vida escolar
Authors: Godínez Mora Andrés , Pescod Vargas Henry , León Carballo Esteban
Published: March 2019

This article reports on the use of the anime Assassination Classroom as a means to construct a political culture in a group of students from Liceo Samuel Saenz Flores, between 2015 and 2016. Based on this, it was attempted to promote critical thinking and to bring together the reality of these youth and the political content of this work. At the theoretical level, the domains of a pluralistic and chrono-holistic political culture were used. In addition, various schools of critical theory of education were used. Methodologically, this research project highlights the use of content analysis and the "anime forum". The main findings allowed to link non-traditional teaching (the anime and its discussion) with the educational reality of the collaborators of this project. In this regard, it allowed to collect and analyse data according to the perceptions of their environment and their role in these dynamics. It also demonstrates the similar problems of the educational systems of Costa Rica and Japan.
Concepciones sobre la enseñanza de conocimientos políticos de profesoras y profesores de la educación escolarizada de la región colombiana del Valle de Aburrá
Authors: Villa Sepúlveda María Eugenia , Pagès i Blanch Joan
Published: March 2019

This text presents a description of some conceptions that guide the teaching of political knowledge of a group of teachers of primary and secondary education in the Colombian region of Valle de Aburrá. Its purpose is to provide some considerations related to the teaching of this knowledge and the training of teachers. It is derived from a research project in which elements of the Collaborative Action Research method were adopted, from the point of view of McKernan, and in which knowledge was constructed around the practices of the teaching staff and understood, from Pagès's concept of Education for the Exercise of Citizenship, as a form of political education which allows to educate to participate actively in the organisation of social life. At the end, some considerations are made of which we can highlight: The imperative of promoting the autonomy of teachers in the context of groups of academic work; the inclusion of resistance processes that emerge in situations of domination as contents to be studied, and the promotion of the teaching methods of activities that emphasize the active participation of students in the processes that entail their education.
Análisis comparativo de los procesos existentes en el campo del emprendimiento en la educación media en Colombia y Ecuador
Authors: Rico Angélica Yadira , Santamaría Marisol
Published: March 2019

The purpose of this article is to present a comparative study of the existing processes in the field of entrepreneurship in secondary education in Colombia and Ecuador. It seeks to understand the actions that have been carried out, to contrast the forms of implementation of this subject in secondary education, and to identify the legal aspects that concern this training.
This research project in comparative education was based on the documentary analysis of laws, curricula and guidelines, which allowed an approximation to two countries with similar profiles in the educational, social and economic spheres, but with different actions in the practical field of entrepreneurship. Among the study findings, the following aspects stand out as common: the existence of norms that regulate the incorporation of entrepreneurship in schools, the compulsory nature of the subject in certain levels of secondary education, in addition to the need to have a unified curriculum. On the other hand, divergences were found in the practical measures adopted to incorporate entrepreneurship education in educational institutions offering secondary education.
La intensificación del trabajo docente en tres países latinoamericanos
Authors: Sánchez Cerón Manuel
Published: March 2019

Changes in the model of capital accumulation in Latin America are transforming the teaching profession. These mutations are located in the phenomenon of precarisation of labour. One of the levels on which this process is observed is the intensification of work. The purpose of this study is to present a general overview of the effects of the intensification of teacher work on teachers in three Latin American countries: Argentina, Brazil and Mexico. This analysis derives from an indicative review of the studies that reflect the consequences of this phenomenon. However, as the subject is broad and complex, this review also considered studies that, even if they did not intend to address this issue, indirectly touch on it. The review identifies four effects that are presented here: One, the increase in working time after hours; two, the increasing diversification of teachers' functions; three, the need for teachers to have other jobs; and four, the problems of professional training after hours.
Relación entre habilidades de pensamiento crítico y rendimiento académico
Authors: Alquichire R. Shirley Lorena , Arrieta R. Juan Carlos
Published: March 2019

The purpose of this research project was to identify the relationship between critical thinking skills and the academic performance of students in the first semester of the Degree in Biology and Chemistry at Universidad del Atlántico. 34 students participated; 59% of the sample consisted of women and 41% of men. The age varied from 16 years to 40 years, with an average of 20.82 years. For the data collection process, the Watson-Glaser Critical Thinking Assessment W-GCTA short test –a psychometric test– was used, and the academic performance was observed in the Admissions and Academic Registration Department of Universidad del Atlántico. It was found that students generally have an average academic performance and are placed in the average category of critical thinking skills. On the other hand, the Pearson correlation coefficient revealed important relationships between the skills evaluated and the academic performance. To verify the results of the Pearson correlation, a one-way ANOVA test was used, which resulted in a difference in the means of the variances, which were not homogeneous and, therefore, did not agree with the literature. Among the pedagogical implications under consideration, taking into account the results, it is necessary that teachers understand themselves as researchers, and in this way promote critical reading as well as critical, creative, reflective and analytical thinking, in order to increase the spectrum of youth opportunities.
Caracterización de la cátedra de emprendimiento en colegios distritales de Bogotá
Authors: Rico Angélica , Santamaría Marisol
Published: March 2019

This article presents a study about the actions that the public schools of a neighbourhood of Bogotá (Colombia) implemented with the purpose of implementing a course on entrepreneurship in secondary education. There are normative elements of the entrepreneurship course in the country, such as Law 1014 of 2006, Law 1429 of 2010 and the policy documents of the National Ministry of Education. The perspectives of teachers, students, managers and the productive sector linked to each institution are contrasted. In addition, a review of documents and experiences of the actors involved in the process is carried out. The participation of the National Apprenticeship Service (SENA) and its role in schools is analysed, as well as the articulation of public educational institutions in Bogotá with higher education. Thanks to the realization of this study it will be possible to provide a clearer vision on the incidence of the culture of entrepreneurship in the educational environment of Bogota. The study shows aspects that can be considered in order to improve their implementation in other educational institutions.
Orientación vocacional. Entre el deseo, el contexto y la historia
Authors: Ochoa Ayala Silvia
Published: March 2019

Vocational guidance is an educational activity that deals with the complexity involved in deciding about the type of training that students will receive, either to join the labour market in the short term, or to continue with higher and postgraduate education. Like any educational activity, it has a history that leaves its mark in its formative work. This study seeks to link the views of the history of guidance from its beginnings in Mexico and to question some current practices, as well as to think of high school students as complex, contextualized beings, beyond the application of tests or invalidating guides that intend to direct youth destiny. Here are presented fragments of vocational stories of a student and seven classmates from the same academic group, who have recently completed their training as technicians in automotive systems at the Center for Scientific and Technological Studies No. 7 of the National Polytechnic Institute (Mexico). Gender, body, age and social inequalities are shown in the life stories, giving an account of the diversity of situations that accompany vocational decisions.
Intestinal P-glycoprotein: pharmacokinetic implications and approaches for enhancement of oral bioavailability of its substrates
Authors: Nivsarkar Manish , Dash Ranjeet Prasad
Published: March 2019

A variety of drug transporters expressed in the body control the fate of drugs by affecting absorption, distribution, and elimination processes. In intestine, the transporters mediate the influx and efflux of endogenous or exogenous substances depending on their affinity to intestinal carrier systems as well as their chemical nature. Of prime interest are drug efflux pumps like P-glycoprotein that are recognized to pose functional role in determining the pharmacokinetics of drugs administered by peroral as well as parenteral route. Various formulation approaches are opted in order to overcome this P-glycoprotein mediated drug efflux. Moreover, broad substrate recognition by this protein and clinical implications of its inhibition lead to design and development of novel P-glycoprotein inhibitors that includes some therapeutic drugs and daily foods and beverages. Inhibition of P-glycoprotein improves intestinal absorption and tissue distribution while reducing the substrate metabolism and its elimination. Some of the pharmaceutical excipients have also shown P-glycoprotein inhibition activity. In this review, we will be discussing about the various approaches that can be explored to reduce P-glycoprotein mediated drug efflux and improve the bioavailability of its substrates.
Antimicrobial Evaluation of Natural Spices (Tumeric, Garlic, Onion, Celery and Cinnamon) Versus Synthetic Antibiotics (Tetracycline, Clindamycin and Ceftriazone) at Three Different Concentrations (10%, 50% and 100%)
Authors: Jagessar RC , Ali F , Shrikant G , Astwood M
Published: March 2019

Most Synthetic drugs have several side effects when administered and the cost of synthesizing them is an expensive endeavour. One alternative is to use herbal medicines. Guyana has an abundance of diverse flora which has been receiving attention in this area. However, much more research needs to be done. The antibacterial activity of natural spices (Tumeric, garlic, onion, celery and cinnamon) was investigated against E. coli, S. aureus, K. pneumoniae and P. aeruginosa and was compared with synthetic antibiotics (Tetracycline, Clindamycin and Ceftriazone) at three different concentrations of 10%, 50% and 100%. The Disc Diffusion Assay was used to investigate the antimicrobial potency of the synthetic drugs and herbal medicines under aseptic conditions. The synthetic drugs were prepared at different concentrations of 10%, 50% and 100%, whereas the extract was investigated at 100% concentration. Experiments were done in triplicates and the diameter of zone of microbial inhibition (DZOI) was measured and expressed as the mean with standard deviation (SD). The precision of comparisons (e.g. 95% confidence intervals) and Area of Zone of Inhibition, AZOI was also computed. Selected microorganisms were also tested against a reference standard antibiotic, Ampicillin and Nystatin. For the synthetic drugs, the highest Area of Zone of Inhibition, AZOI of 1566.4 mm2 was induced by Clindamycin against S. aureus at 50% concentration whereas the lowest AZOI of 245.09 mm2 was induced by P. auriginosa at 10% concentration. For the herbal extracts, the highest AZOI of 1256.6 mm2 was induced by the onion extract versus K. pneumonia whereas the lowest AZOI of 50.3 mm2 was induced by the Tumeric extract against E. coli. Antimicrobial selectivity was also observed for both synthetic and herbal medicines. For example, for tetracycline against S. aureus, AZOI of 1093.92 mm2 was obtained whereas against P. auriginosa, AZOI of 530.67 mm2 was observed. Garlic exhibited AZOI of 139.49 mm2 against E. coli whereas a value of 78.5 mm2 was obtained against P. aeruginosa.
A Case Report of One Patient with Allergic Purpura Induced by Voriconazole
Authors: Qiu Zhihong , Qi Benquan , Liu Hongtao , He Lien , Ma Yinling , Song Haojing , Yu Meiling
Published: March 2019

Voriconazole is a second-generation triazole antifungal drug, which exhibits characteristics of wide antibacterial spectru, high biological utilization and passing through plasma brain barrier. The most common adverse reactions of voriconazole include neurological dysfunction, visual disturbance, abnormal liver function and renal dysfunction, here, this is the report to show that voriconazole can induce allergic purpura. The present report mainly describes one patient with rare adverse reactions, namely mixed type allergic purpura induced by high concentration of plasma drug caused by slow metabolism of voriconazole. Aafter using voriconazole, the patient was diagnosed as mixed type allergic purpura, methylprednisolone sodium succinate was given for treatment. After treatment, abdominal pain and abdominal distension of the patient was significantly alleviated, and the color of rash faded. Edemas of both lower extremities were significantly improved, and the color of stool turned into yellow. The measured concentration of plasma drug of voriconazole was 15 Î¼g/ml on admission of the patient. Genetic testing result demonstrated that the patient belonged to heterozygous mutation of CYP2C19*1*2, and the metabolism of voriconazole of the patient was relatively slow. The report prompted the clinicians that there were significant metabolic differences of voriconazole in different populations. Therefore, monitoring of drug concentration should be conducted timely in the clinical application to reduce the risk of medication and achieve individualized administration.
The Post-Ischemic Increase in GluA2 Ser880 Phosphorylation Involves NADPH Oxidase
Authors: Jackson Darrell A. , Astruc-Diaz Fanny , Byrnes Nicole M. , Beske Phillip H.
Published: March 2019

Most 2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl) propanoic acid receptors (AMPARs) expressed on adult hippocampal pyramidal neurons contain the edited form of GluA2 (Q607R) and are thus impermeable to Ca2+/Zn2+ entry.  Following ischemic injury, these receptors undergo a subunit composition change, switching from a GluA2-containing Ca2+/Zn2+-impermeable AMPAR to a GluA2-lacking Ca2+/Zn2+-permeable AMPAR. Recent studies indicate that an oxidative stress signaling pathway is responsible for the I/R-induced changes in AMPAR subunit composition.  Studies suggest that nicotinamide adenine dinucleotide phosphate-oxidase (NADPH oxidase), a superoxide generator, is the source that initiates the oxidative stress-signaling cascade during post-ischemic reperfusion. The objective of the present study was to determine if suppression of NADPH oxidase activity prevents the increase in phosphorylation and subsequent internalization of the GluA2 AMPAR subunit during reperfusion of post-ischemic hippocampal slices. In this study, we demonstrated that exposure of adult rat hippocampal slices to oxygen glucose deprivation/reperfusion (OGD/R) results in an increase in Ser880 phosphorylation of the GluA2 subunit.  The increase in Ser880 phosphorylation resulted in the dissociation of GluA2 from the scaffolding proteins Glutamate receptor-interacting protein 1 (GRIP1) and AMPAR binding protein (ABP), thus enabling the association of GluA2 with protein interacting with C kinase 1 (PICK1). OGD/R also resulted in an increase in the association of activated protein kinase C ? (PKC?) with PICK1. We have found that pharmacological inhibition of NADPH oxidase with apocynin diminishes the OGD/R-induced increase in activated PKC? association with PICK1 and subsequent Ser880 phosphorylation of GluA2. Suppression of NADPH oxidase activity also blunted OGD/R-induced decreased association of GluA2 with the scaffolding proteins GRIP1 and ABP.  Protein phosphatase 2A (PP2A), which regulates PKC? activity by dephosphorylating the kinase, was inactivated by OGD/R-induced increase in tyrosine phosphorylation of the phosphatase (Y307). Inhibition of NADPH oxidase activity ameliorated OGD/R-induced PP2A phosphorylation and inactivation. Our findings are consistent with a model of OGD/R-induced Ser880 phosphorylation of GluA2 that implicates NADPH oxidase mediated inactivation of PP2A and sustained PKC? phosphorylation of GluA2.
Intraocular Pressure Control for Patients Undergoing Combination Intravitreal Anti-VEGF and Dexamethasone Therapy for Macular Edema from Retinal Vein Occlusion
Authors: Singer Michael , Bell Darren , Singer Joshua , Woods Paul , Jergensen Tyson R. , Yanev Petar G. , Iltis Joshua M. , Tyler Lyndon D. , Beck Kinley D.
Published: March 2019

Background and Objective: Sustained-release dexamethasone intravitreal implant is an effective treatment for macular edema secondary to retinal vein occlusion (RVO) but ocular hypertension is a side effect. This study evaluated whether the addition of a single combination IOP-lowering medication will reliably control intraocular pressure (IOP) for those patients.   Study Design/Patients and Methods: Retrospective chart review of 62 patients that underwent multiple injections of combination anti-VEGF and sustained-release dexamethasone intravitreal implant for macular edema secondary to RVO. IOP spikes were treated with brimonidine 0.2% - timolol 0.5%. IRB approval was obtained.   Results: The average elevated IOP requiring treatment was 28.6 mmHg. The average IOP after adding brimonidine 0.2% - timolol 0.5% was 16.7 mmHg. 100 percent of treatment cycles had an IOP< 30 mmHg after starting treatment.   Conclusions: Using one combination IOP-lowering drop can reliably control the ocular hypertension that occurs secondary to combination therapy for macular edema in RVO.
A Case Report on Warfarin Induced Skin Necrosis: Drug-drug Interaction or Inappropriate Therapy
Authors: S Dutta , PK Sharma , AK Misra , R Kumar , S Rai , R Chaudhary
Published: March 2019

Introduction: Warfarin is one of the most frequently prescribed oral anticoagulant. Necrosis and/or gangrene ofskin and other tissues is an uncommon but serious risk associated with warfarin. The incidence of warfarin inducedtissue necrosis is about 0.01 % to 0.1%.Case description: A 62-year-old male presented to emergency with a complaint of skin discoloration and edema onleft lower limb diagnosed as warfarin induced skin necrosis. He had an episode of hemiparesis 20 days back for whichhe was started on oral warfarin along with other medications. On diagnosis warfarin was stopped and fresh frozenplasma (FFP) was given along with vitamin K. Due to progressing tissue necrosis, above knee limb amputation wasdone. We assume that an interaction between rosuvastatin and warfarin or possibly lack of adequate bridge therapywith heparin resulted in this complication.Conclusion: Warfarin induced skin necrosis is a known early complication of the therapy. Though late onsetappearance of this event is rare but not unknown. Bridging therapy with heparin and avoiding use of interactingdrugs concomitantly could prevent many such reactions.
Application of Molecularly Structured Ben Oil in Gentamicin Entrapped Lipospheres
Authors: Chime Salome A. , Onyishi Ikechukwu V. , Eze Ifeoma O.
Published: March 2019

Objective: To formulate extended release gentamicin-entrapped lipospheres using natural lipids from Irvingia wombolu (IWF) and Moringa oleifera seed (MO) popularly known as Ben oil. Methods: Different lipid combinations including IWF and Phospholipon 90H (P90H) and IWF and MO were employed in the formulation of lipospheres. The formulations were analysed for particle size, encapsulation efficiency (EE), pH stability and antimicrobial studies amongst other tests. Also the in vitro release properties were studied in Phosphate buffer pH 7.2. Results: High EE of up to 90 % were obtained for the various LM combinations. The pH was stable over 30 days and the formulations showed about 93 % release of gentamicin at 12 h. Lipospheres formulated with MO matrices showed synergism in the microbial inhibition than other formulations. Conclusion: Natural lipids from Irvingia wombolu and Moringa oleifera seed could be used in formulating oral extended release gentamicin lipospheres.
Evaluation of Antimicrobial Effect against Some Microorganisms and Apoptotic Activity against Candida Species of New Vanillin Derivatives
Authors: ÜNVER Hakan , CANTÜRK Zerrin , ÖZARDA M. Güçlü
Published: March 2019

Eleven vanillin derivatives was synthesized, characterized successfully
and their antibacterial and anticandidal properties were investigated on seven
bacterial species and four candida species. These bacterial species are Staphylococcus aureus, Enterococcus faecalis, Listeria monocytogenes, Klebsiella pneumoniae, Pseudomonas aeruginosa, Escherichia coli, and Bacillus subtilis and candidal species
are Candida albicans, Candida glabrata,
Candida krusei and Candida
parapsilosis. Most of the synthesized compounds were showed good activity
against studied microorganisms compared with Chloramphenicol. Compounds 2c, 2d
and 2k were exhibited remarkable antibacterial activities especially on Escherichia coli. In addition, Klebsiella pneumoniae, Pseudomonas aeruginosa and Bacillus subtilis were found to be the
most susceptible species amongst the investigated microorganisms
POSSÍVEIS IMPACTOS DE FAKE NEWS NA PERCEPÇÃO-AÇÃO COLETIVA
Authors: Moroni Juliana
Published: March 2019

O objetivo deste trabalho é investigar a relação entre fake news 3 , padrões informacionais e percepção-ação coletiva, a partir do paradigma da complexidade. Nesse sentido, analisamos, neste trabalho, o seguinte problema: Qual a influência da disseminação de fake news, disponíveis nos meios digitais, na percepção-ação coletiva? Argumentamos em defesa de que as hipóteses do paradigma da complexidade oferecem subsídios teóricos inovadores para a análise de temas e de problemas sobre a relação entre fake news e percepção-ação coletiva. Nosso desafio será fornecer subsídios para opressuposto de que fake news, disponíveis nos meios digitais, proporcionam a emergência de padrões informacionais coletivos que podem alterar hábitos sociais bem estabelecidos. Nosso pressuposto principal é o de que essas alterações ocorrem devido à influência negativa da manipulação de informação através de fake news nas propriedades de prospectividade, flexibilidade e coordenação emergente relativas à percepção-ação humana.
PERSPECTIVAS DO CROSS-CULTURE PARA BIBLIOTECAS HÍBRIDAS
Authors: Caldas Rosangela Formentini , Silva Rafaela Carolina
Published: March 2019

Nos costumes, histórias, leis, hábitos e comportamentos cotidianos, existe o modo de como as bibliotecas irão interagir com seus usuários. A maneira pelas quais uma biblioteca cria, organiza e dissemina a informação se transformam de acordo com as mudanças culturais vivenciadas. Assim, as Tecnologias de Informação e Comunicação vêm agregar valor às tecnologias analógicas de tratamento da informação para as bibliotecas híbridas, tornando-se necessário o entendimento acerca da cultura institucional para uma melhor atuação de tais instituições em suas comunidades. Nesse cenário, o método Cross-Culture destaca-se como uma metodologia de pesquisa que permite o entendimento das diferentes realidades das bibliotecas híbridas, a partir do reconhecimento da interculturalidade existente nesses ambientes. O objetivo do estudo compreendeu verificar o método Cross-Culture como uma metodologia passível de caracterizar os elementos que fundamentam o conceito de bibliotecas híbridas. A pesquisa caracterizou-se por ser de natureza qualitativa e exploratória. O método escolhido foi a Pesquisa Bibliográfica, utilizando-se das bases BRAPCI e SciELO pois correspondem a área da Ciência da Informação no âmbito internacional. O levantamento dos artigos deu-se por meio das palavras-chave “bibliotecas híbridas”, “hibridez em bibliotecas”, “conceito de bibliotecas híbridas” e “desenvolvimento cultural”. Como resultados, observou-se que o método Cross-Culture permite a visualização da hibridez em bibliotecas como ação indispensável para a promoção do acesso e atendimento às necessidades do público com quem atuam, uma vez que abarcam a convergência de informações, ferramentas, serviços e processos para que suas comunidades se desenvolvam. As bibliotecas híbridas podem ser conceituadas como equipamentos culturais que abrangem não somente políticas institucionais, mas a interligação destas com as políticas públicas que regem a cultura do seu público-alvo. Assim, ao se trabalhar com as políticas públicas inerentes a cada cultura, percebeu-se que o conceito de bibliotecas híbridas traz uma proposta de interculturalidade dentro dos equipamentos culturais. Nessa perspectiva, a biblioteca híbrida possui princípios institucionais flexíveis, que se moldam de acordo com o enfoque de cada localidade.
A MATÉRIA E SUAS TRANSFORMAÇÕES: A RELAÇÃO ENTRE CORPO E MENTE, SEGUNDO DIDEROT
Authors: Santos Danielly Lima dos , Portich Ana Maria
Published: March 2019

Neste trabalho, será exposto o materialismo defendido por Diderot n’O Sonho de D’Alembert. Nesse texto redigido a partir de 1769, Diderot trata da relação entre corpo e mente por um viés materialista/monista, explicando como duas coisas aparentemente tão diferentes como o pensamento,imaterial e indivisível, e o corpo, material e divisível, estão conectadas. Descarta diretamente o dualismo substancial cartesiano, deixando claro que tudo é matéria (sensível), e a diferença se dáapenas na sucessiva transformação da matéria de sensibilidade inerte para matéria de sensibilidade ativa. Ou seja, do não inteligente deriva o inteligente. Diderot trata ainda da questão do eu sob um viés materialista e até certo ponto determinista. Diderot compara o eu a um feixe de fios, demostrando qual o processo de transformação que esse feixe de fios passou para chegar na forma atual de feixe de fios: ele era algo imperceptível, formado pelas moléculas de seu pai e sua mãe, tornou-se um fio delgado e depois um feixe de fios. Por um processo de nutrição e transformação das moléculas, cada fibra do feixe de fios se transforma em um órgão, extremamente suscetível à sensibilidade. Algumas dassensações percebidas são mais fracas, outras mais marcantes, e para Diderot são essas sensações mais marcantes que darão origem à memória, logo são elas que possibilitam a ideia de um eu. Mas Diderotvisualiza o eu como uma ilusão criada por nós, pois, na sucessiva transformação do todo que é a matéria, cada indivíduo é alterado. Participamos desse todo travestido em várias formas, não tendoassim o conhecimento do que seremos daqui a um ano ou um século, por isso é necessário observar o processo de transformações sucessivas por que a matéria passou para chegar à forma atual. Portanto, só podemos conhecer a natureza do pensamento através do processo de transformação da matéria.
Diagnóstico bucal precoce no SUS: análise individual, vigilância à saúde e trabalho em equipe como possibilidade (re)estruturante
Authors: Melo Nilce Santos de , Figueiredo Paulo Tadeu de Souza , Leite André Ferreira , Souza Tiago Araújo Coelho de , Lucena Edson Hilan Gomes de , Zanetti Carlo Henrique Goretti
Published: March 2019

O artigo se estrutura em dois estudos exploratórios sobre o exercício do diagnóstico clínico de lesões bucais no SUS. Os dados foram obtidos por meio de questionários, aplicados durante atividades de educação continuada. Aproximadamente 300 cirurgiões-dentistas que atuam na atenção básica responderam. Para a maioria (79,5%), há tempo, infraestrutura e intenção de realizar diagnóstico precoce. Por outro lado, os profissionais manifestaram dificuldades em realizar o exame clínico voltado para o câncer, por necessitarem de mais informações sobre a doença. Os resultados serviram de base para apresentar a interpretação auto-referida do cirurgião-dentista, no plano individual, bem como serviram de base para, a partir da revisão bibliográfica, apresentar a interpretação individual sob marcos conceituais da saúde comportamental (teoria do comportamento planejado), na perspectiva individual; e a interpretação da sociologia das profissões e das teorias de planejamento e programação para a promoção e vigilância em saúde, na perspectiva coletiva.
РЕЧНИК ПРИЧЕ О БОЈУ КОСОВСКОМ (РУКОПИС ИЛИЈЕ ЈОВАНОВА)
Authors: Бајић Весна
Published: March 2019

Овај рад представља речник једне од верзија Приче о боју косовском – Рукописа Илије Јованова, који је настао средином XVIII века. На основу појединих речи, попут чоек, претпоставља се да је могао настати у Црној Гори. Текст је писан старосрпским језиком, са ретким лексичким наносима из српскословенског језика (нпр. дашти), брзописом и неуређеним правописом, а одликује га присуство и јекавских и екавских форми. С обзиром на то да лексика предстандардног периода развоја српског народног језика до данас није систематски проучена, овај рад представља скромни допринос познавању састава лексикона српског језика ове епохе.
AHP Metoduyla Yer’e Özgü Mimari Tasarım Kriterlerinin Öncelik Sırasının Belirlenmesi
Authors: Yıldız Kuyrukçu Emine , Alkan Ahmet
Published: March 2019

20.
yüzyılda küreselleşme ile mimari tasarımın yerle olan ilişkisi kopmuş, her
türlü bölgesel sınır ortadan kalkmıştır. Bu bağlamda mimarlık, bölgesel bir
olgu olmaktan çıkmış, artık sınırları olmayan evrensel bir olgu haline
gelmiştir. Çalışma, ‘mimari tasarım-yer’
ilişkisini doğru kurmanın yani yerin ruhunun somutlaştırılmasının yolu olarak Eleştirel Bölgeselciliğin çözüm
olabileceğini savunmaktadır. ‘Eleştirel
Bölgeselcilik (Critical Regionalism)’ yaklaşımında ‘yer’e ait değerlerle, çağdaş yer yönelimli tasarım yapmak
amaçlanmaktadır. Çalışma kapsamında Eleştirel Bölgeselcilik kavramını
geliştiren Kenneth Frampton’ın 1987’lerde söylemleştirdiği 10 maddesi
yorumlanarak dokuz kriter belirlenmiş ancak bu kriterlerin günümüz koşullarında
yetersiz olduğu düşünülerek tarafımızdan dört kriter eklenerek “bir yapıyı eleştirel rejyonalist-o yer’e
(bölgeye) ait” olarak nitelendirebilmenin on üç evrensel kriteri, dört grup
halinde ortaya konulmuştur. Çalışmanın asıl amacı bir yapının eleştirel
rejyonalist-o yer’e (bölgeye) ait olarak adlandırılabilmesi için hangi
kriterlerin etken olduğu ve bu kriterlerin öncelik sıralamasını tespit
etmektir. Bu doğrultuda doktor unvanına sahip Selçuk Üniversitesi, Gazi
Üniversitesi, Orta Doğu Teknik Üniversitesi’nden Restorasyon Anabilim Dalı,
Mimarlık Tarihi Anabilim Dalı, Bina Bilgisi Anabilim Dalında görevli toplam 34
uzmandan, bir tasarımın o yere ait olarak algılanmasında belirlenen kriterlerin
ne kadar etken olduklarını puanlamaları istenmiştir. Sonuçlar AHP (Analitik
Hiyerarşi Prosesi) metoduyla analiz edilmiş ve çalışma kapsamında ortaya
konulan kriterlerin geçerliliği ve tüm bu kriterlerin öncelik sırası
belirlenerek “bir yapıyı eleştirel
rejyonalist-o yer’e (bölgeye)” ait olarak nitelendirmede öncelikli
kriterler tespit edilmiştir.
Ciência brasileira em crise: a ciência em rede como estratégia de enfrentamento
Authors: Leta Jacqueline , De Araújo Kizi Mendonça , Da Silveira Guedes Vânia Lisboa
Published: March 2019

Editorial
A internacionalização nas Geociências da USP: comparação entre coberturas da Web of Science e da Scopus no nível micro
Authors: Santana Anderson de , Mugnaini Rogério
Published: March 2019

O estudo analisou a internacionalização da produção científica individual de pesquisadores do Instituto de Geociências da Universidade de São Paulo (IGc/USP) por meio de indicadores bibliométricos. Trata-se de um estudo de caso, com levantamento de dados e análise bibliométrica, e abordagem exploratória e descritiva. Foi definida uma amostra de 18 pesquisadores, cuja produção foi analisada segundo três categorias de indicadores: produção (nas fontes Dedalus/USP, Web of Science e Scopus), impacto e colaboração (somente nas bases internacionais). Com base nos resultados pôde-se constatar que a maioria dos pesquisadores da amostra aumentaram seu nível de publicação internacional. Além disso, sua produção se mostrou mais representativa na Scopus, quando comparada por meio de indicadores baseados em números absolutos de documentos indexados e citações recebidas. Contudo, ao se considerar indicadores normalizados, a vantagem da Scopus não se pronunciou na mesma magnitude, ainda que tenha sobressaído. Por fim, não se pode ignorar as especificidades das áreas, que se evidenciam nas práticas de comunicação científica, que inclui diversos fatores de escolha dos periódicos científicos, consequentemente implicando na internacionalização.
Integração de bases de dados em estudos bibliométricos: a produção científica nacional em Zika vírus
Authors: Alencar Maria Simone de Menezes , Bochner Rosany , Giacometti Daniel
Published: March 2019

A partir do estudo de caso da produção científica brasileira envolvendo o vírus Zika, este artigo tem como objetivo discutir a importância da integração de dados de diferentes fontes para melhor representar o universo da pesquisa, destacando como a restrição de fontes impacta nos resultados de análises bibliométricas. Para identificação da produção brasileira na área por meio da seleção de artigos de periódicos com pelo menos um autor brasileiro, foram utilizadas quatro bases informacionais: duas fontes gerais, a Web of Science e a Scopus; uma fonte específica da área de estudo, o PubMed; e uma fonte de pesquisa de informação nacional, a SciELO. A análise dos resultados indica a relevância da integração de diferentes bases de dados em estudos bibliométricos como meio de minimizar distorções e fornecer uma visão consistente do universo da pesquisa científica em determinado tema.
Associação do Fator de Impacto e do Índice h para a avaliação de periódicos científicos: uma aplicação no campo da Ciência da Informação
Authors: Silva Deise Deolindo , De Almeida Cátia Cândida , Grácio Maria Cláudia Cabrini
Published: March 2019

Os indicadores bibliométricos oferecem relevante subsídio ao processo avaliativo da produção científica, especialmente em nível meso e macro, e para as tomadas de decisões em políticas científicas. Dentre eles, destacam-se o Fator de Impacto e o Índice h. Criado para a avaliação de impacto de periódicos científicos, o Fator de Impacto é definido como a média de citações recebidas por um periódico científico em um determinado período. O Índice h considera em sua formulação aspectos relativos ao impacto científico (citação) e à produtividade (número de artigos produzidos) de um pesquisador. Diante da importância contemporânea desses indicadores, esta pesquisa objetiva propor uma forma de avaliação de periódicos científicos, combinando o Fator de Impacto e o Índice h, a fim de contribuir para a discussão da necessidade de uma avaliação multidimensional nos processos avaliativos. Levantaram-se os valores do Fator de Impacto e do Índice h dos 168 periódicos científicos consignados à Ciência da Informação, indexados na base de dados Scopus durante os anos 2012, 2013, 2014 e coletados por meio do portal SCImago Journal & Country Rank. Entre os resultados, observou-se que, embora haja uma tendência de posicionamento similar quanto a esses indicadores, para uma parcela significativa de periódicos as tendências são discordantes. Conclui-se que a utilização conjunta dos indicadores Fator de Impacto e Índice h contribui para uma avaliação mais precisa dos periódicos científicos.
Mapeamento do conhecimento científico: uma proposta de método baseado em Genealogia Acadêmica
Authors: Rossi Luciano , Mena-Chalco Jesús Pascual
Published: March 2019

A estruturação do conhecimento fornece os meios para organizar o saber formal em categorias que facilitem sua gestão e contribuam para sua disseminação. Entretanto os modelos formais de classificação do conhecimento não permitem a observação das relações existentes entre as diferentes categorias ou do fluxo desse conhecimento entre membros da comunidade científica. Neste trabalho, buscamos estruturar o saber científico, representado por mapas da ciência, considerando a estrutura hierárquica fornecida pela Genealogia Acadêmica. Utilizamos, como estudo de caso, a descendência acadêmica de Johann Bernoulli representada em forma de grafo de genealogia e as informações biográficas disponibilizadas pelo Wikipedia em concordância com o padrão desenvolvido pelo Mathematics Subject Classification, além de um glossário de áreas da matemática. Para inferir os tópicos do conhecimento aos matemáticos que não possuíam informações, utilizamos um procedimento de propagação de tópicos que considera a topologia do grafo de genealogia. Consideramos que identificar e estudar o fluxo do conhecimento científico entre gerações de pesquisadores é uma tarefa importante para entender como o conhecimento do estado da arte foi difundido. Contudo, no nosso entendimento, essa tarefa foi pouco explorada pela comunidade científica devido à inexistência de conjuntos de dados. Acreditamos que este trabalho permitirá a definição de um novo método computacional para o estudo de fluxo de conhecimento. A relevância do trabalho recai na possibilidade de descoberta de novas informações que auxiliem a identificar, analisar e estruturar os mapas da ciência.
A influência de outliers nos estudos métricos da informação: uma análise de dados univariados
Authors: Maia Lima Luís Fernando , Maroldi Alexandre Masson , Silva Dávilla Vieira Odízio da , Hayashi Carlos Roberto Massao , Hayashi Maria Cristina Piumbato Innocentini
Published: March 2019

Este artigo apresenta uma nova fórmula de detecção de outliers via Análise Exploratória de Dados, levando em conta a assimetria dos dados, e também estuda o efeito da remoção dos outliers dos dados originais. Aplica-se a fórmula para três conjuntos de dados publicados na literatura de estudos métricos da informação. O primeiro conjunto de dados apresenta cinco outliers inferiores. A média, dos dados agregados, conduz à falsa impressão de que 40 universidades, de um total de 49, estão acima da média. A remoção dos cinco outliers inferiores conduz a uma nova média em que somente 22 universidades estão acima da média. No segundo conjunto de dados há a presença de cinco outliers inferiores e um outlier superior. Neste caso, o outlier superior ameniza o efeito dos outliers inferiores. No terceiro conjunto de dados, detectam-se cinco outliers superiores e um outlier inferior. A média, dos dados agregados, aponta que dez universidades estão acima da média. Removendo-se os seis outliers dos dados originais, encontra-se que 28 universidades estão acima do novo valor da média. Para os três conjuntos de dados analisados o trabalho também demonstra o efeito dos outliers na estimativa intervalar (inferência estatística): a remoção dos outliers gera valores mais representativos tanto para a média como para o desvio padrão da amostra analisada. Portanto, evidencia-se como outliers podem afetar resultados e conclusões nos estudos métricos da informação. Todavia, a fórmula para a detecção de outliers apresenta-se aberta para futuras pesquisas.