bluuebunny/crossref_metadata_2025 huggingface dataset:
La langue entre écrit et oral
Authors: Hnilicová Karolina
Published: December 2021

La communication dans toutes les langues peut prendre soit la forme orale, soit la forme écrite. Ces formes peuvent partager certaines caractéristiques ou, au contraire, elles peuvent se différer complètement. Quelques particularités sont liées aussi au français écrit et oral, comme c’est d’ailleurs montré dans la première partie de cet article. Son objectif est, cependant, d’étudier plus aux détails ces particularités sur un genre médiatique spécifique. Ainsi, connaissant des phénomènes traditionnellement associés à la communication orale et écrite en français, cet article cherche et montre leur présence dans une émission radiophonique Pop & Co, qui appartient au genre de la « chronique de radio ». Même si ce genre paraît bien connu par des auditeurs francophones, les chroniques semblent toujours mal décrites en ce qui concerne leur structure et l’emploi du langage. Parmi les caractéristiques communes à plusieurs genres radiophoniques, celle qui ressort pour les chroniques est leur préparation sous forme textuelle suivie de la lecture à haute voix à la radio. La combinaison du français écrit et oral ainsi que la recherche linguistique médiocre dans ce domaine nous ont amenés à l’investigation plus détaillée de ce genre. L’analyse que nous proposons se focalise sur l’observation non seulement de la structure de l’émission mais aussi de la présence des constructions linguistiques traditionnellement liées au français écrit ou oral. Ainsi, cette analyse se donne pour objectif de situer la « chronique » sur le continuum linguistique écrit/oral, et de dire en quoi on peut y voir une combinaison équilibrée des deux.
Quelques remarques sur la vie et l'œuvre de Jean Vodaine, pour honorer le centenaire de sa naissance
Authors: Ferlež Urh
Published: December 2021

L’article est écrit pour honorer le centenaire de la naissance du poète, typographe, peintre, imprimeur et éditeur Jean Vodaine. Il est né à Čiginj, en Slovénie, le 6 juillet 1921, dans une famille ouvrière qui déménagé en Lorraine en 1924. Au début de sa carrière, Jean Vodaine travaille comme ouvrier parallèlement à ses activités artistiques. Après un grave accident, il se consacre entièrement à l’art. Il est le fondateur de Dire, revue littéraire régionale mais de portée internationale, autour de laquelle il réunit des poètes du monde entier. Il l’a lui-même mise en page et imprimée sur sa propre presse. Il a mis l’accent sur la conception typographique des textes, ce qui fait de ses revues des Gesamkunstwerks. L’importance de son travail réside dans le fait qu’il ait réussi à apporter la culture dans une région culturellement moins développée profitant de sa position « carrefour » où se sont rencontrées les influences et les artistes allemands, français, belges, luxembourgeois et immigrés.  Il avait des liens avec le cercle des artistes de l’art brut dont plusieurs membres, comme Vodaine, appartenaient à la classe ouvrière. Pour les Slovènes, il est important en tant que promoteur de la poésie slovène en France. Sa double identité nationale et linguistique aussi bien que la qualité de ses œuvres le rendent intéressant du point de vue biographique ainsi que du point de vue esthétique encore au 21ème siècle, bien qu’il soit relativement inconnu dans son pays natal. Jean Vodaine est décédé le 8 août 2006.
Traduction des connotations autonymiques dans trois romans de Michel Houellebecq
Authors: Gacoin-Marks Florence
Published: December 2021

This paper deals with the autonyms or the widespread, orthographically indeterminate use of italics and quotation marks in Slovene translations of three of Houellebecq’s novels, which have been elaborated by three different Slovene translators. Autonyms are divided into three main categories according to whether they convey the words of definite or indefinite individuals, the language of the narrator himself or the concepts and values of the whole society. Within the framework of a style often qualified as “white”, the extended use of italics and quotation marks with function of autonymic connotation allows the author to transmit to the reader very fine semantic nuances and contributes to the richness of his work. Like metaphorical networks, stylems such as the recurrent and extended use of italics and quotation marks require from the translator a preliminary work of interpretation and the development of a coherent strategy making it possible to preserve intact the function of these elements in the narrative. Although the three translations analysed can be considered as globally faithful to Houellebecq’s texts and made possible the notoriety of the French writer in Slovenia, none of them is distinguished by a rigorous and coherent treatment of autonymic connotations indicated by non-normative use of italics and quotation marks. The most frequent and damaging anomalies are the maintenance of these visual signs where the expressions indicated in French do not have to be in Slovenian or, on the contrary, their elimination where it is perfectly possible and appropriate to maintain them for the detailed understanding of the text. The author draws attention to possible solutions and opts for the elaboration of a consistent translation strategy for the treatment of the analysed elements.
Potential Effect of Informal Learning of English Through Watching a Medical Television Series on the Development of Maritime Medical English Competence
Authors: Jurkovič Violeta
Published: December 2021

As a result of the widespread use of online technologies and vast opportunities for the use of English in everyday online life, the field of online informal learning of languages, in particular English, has attracted a new wave of research attention. Nevertheless, the number of corpus studies in this field remains low. More specifically, to date no research study has focused on the suitability of the language input to which online users are exposed while performing online activities with regard to the development of language skills in English as a language for specific purposes. In order to bridge this research gap, the objective of this paper is to apply the corpus approach to examine whether watching a medical television series may have an effect on the development of medical Maritime English for future deck officers. The results indicate that in terms of lexical density, lexical diversity, terminology, and word clusters, watching a medical television series may have a limited effect on the development of medical Maritime English for future deck officers. However, future research should examine whether watching television series may have an effect on the acquisition of typical speech patterns in spoken maritime communication, which are closely related to everyday spoken communication. Importantly, the results also seem to indicate that online informal learning of English cannot replace all segments of the formal learning of English for Specific Purposes, but can significantly contribute to the development of general English competence, which is a precondition for the further development of discipline-specific language competence.
L’apposition en français et en slovène
Authors: Mezeg Adriana
Published: December 2021

This article first gives an overview of the different uses of French apposition and then focuses on nominal appositions, a kind of supplementive clause introduced by a nominal group (NG) without an article. Only translations of initial nominal appositions are examined, i.e. those which are placed at the beginning of the sentence and where the content of the initial structure is expressed by an apposition or NG as the subject. In this context, word order and the use of commas are discussed, which are often of importance for Slovenian language users. Based on the FraSloK corpus, the following conclusions can be drawn: (a) sentence-initial position is maintained much more often in novels than in newspaper articles; (b) the expression of the content of initial structures with an apposition and an NG, which functions as a subject, is fairly evenly represented in more than half of the cases from newspaper articles, while in novels the subject function is prominent; (c) apart from the change in sentence position, Slovenian apposition corresponds to the source structure, and when its content is expressed by an NG with subject function, there are changes at different levels compared to French; (d) the (non-)use of the comma cannot be satisfactorily justified on the basis of the present corpus, but the examples suggest that it is based on translators’ personal choices and also depends on the possibilities of expression in the target language. Suggestions have already been made to change the rules and usage examples, which are not tenable in our cases, and would require further consideration.
A simple method to produce fragment seedstock for aquaculture of Pterocladiella capillacea (Gelidiales, Rhodophyta)
Authors: Choi Chang Geun Choi , Lee Ju Il Lee , Hwang Il Ki , Boo Sung Min
Published: December 2021

Raw material of gelidioid red algae yielding high-quality agar has been in short supply due to overharvesting, but in situ farming of gelidioids has not been practical due to their slow growth. To produce vegetative seedstock of a cosmopolitan species, Pterocladiella capillacea, we investigated the number and length of regenerated branches arising from sectioned fragments during 3 weeks of laboratory culture at 10, 15, 20, and 25°C. All sectioned fragments formed axis-like branches mostly from the upper cut edge and stolon-like branches mostly from the lower cut edge, showing a high capacity of regeneration and intrinsic bipolarity. At 20°C, the number of regenerated branches increased to 2.74 ± 1.29 on the upper cut edge and 4.26 ± 2.66 on the lower cut edge. Our study reveals that the use of fragments bearing regenerated branches as seedstock can be a simple method to initiate fast propagation for mass cultivation in the sea or outdoor tank.
Temperature ranges for survival and growth of juvenile Saccharina sculpera (Laminariales, Phaeophyta) and applications for field cultivation
Authors: Kim Soo Hong , Kim Young Dae , Hwang Mi Sook , Hwang Eun Kyoung , Yoo Hyun Il
Published: December 2021

Saccharina sculpera is highly valued for human consumption and value-added products. However, natural resources of this kelp have decreased sharply and it is in danger of extinction. Resources recovery through cultivation is being trialed to enable the sustainable use of this species. In this study, the temperature range for survival and optimal growth of juvenile S. sculpera was identified and applied to field cultivation. This study investigated the survival and growth of juvenile S. sculpera under six temperatures (i.e., 5, 10, 15, 16, 18, and 20°C) and two light intensities (i.e., 20 and 40 μmol photons m-2 s-1) in an indoor culture experiment. In these experiments, the blade length decreased at 16°C under the both light intensities. The thalli died at 20°C and 20 μmol photons m-2 s-1, and at 18‒20°C and 40 μmol photons m-2 s-1. During the field cultivation, early growth of S. sculpera was highest at the 5 m depth and growth decreased as the water depth increased. When the initial rearing depth was maintained without adjustment throughout the cultivation period (from December to October), all the cultivated S. sculpera plants died during August and September. However, S. sculpera plants lowered from 5 to 15 m and grew to 90.8 ± 13.1 cm in July. The seawater temperature at 15 m depth was similar to the upper level of thermal tolerance demonstrated by juvenile S. sculpera in the indoor culture experiments (16°C or lower). The plants were subsequently lowered to 25 m depth in August, which eventually led to their maturation in October. The present study confirmed that improved growth rates and a delay in biomass loss can be achieved by adjusting the depth at which the seaweeds are grown during the cultivation period. These results will contribute to the establishment of sustainable cultivation systems for S. sculpera.
Hinduism in the Socio-Political Life of India
Authors: Shaumyan T. L.
Published: December 2021

The article analyzes the importance of the religious factor in determining the ways of socio-political development of India. India remains a country with a multi-confessional population with a clear predominance of adherents of Hinduism. In addition to the infl uence of Hinduism on the life of orthodox society, where castes still play a special role, which determine the norms of behavior and rules of communication, the author analyzes the role of religion in the political agenda of the country. Under the conditions of colonialism, Hinduism was established as a national religion and the basis of a national tradition. The active involvement of Hinduism in political life began at the end of the nineteenth century, when such political parties as the Muslim League and Hindu Mahasabha appeared. The task of the latter was to create a Hindu state in India. The author also pays special attention to the analysis of the formation of the Bharatiya Janata Party, which is characterized as the political wing of a group of Hindu nationalist organizations. The growing popularity of this party, which won the elections in 2014 and 2019, indicates the strengthening of the positions of communalist organizations. These trends show that the active inclusion of religion in the political agenda aff ects the nature of the country’s democratic institutions, gradually transforming the popular thesis that India is a country representing “unity in diversity”.
Rationalization and ‘Religization’ in the Modern Theory of International Relations.
Authors: Reinhardt R.
Published: December 2021

Р.О. Райнхардт – доцент кафедры дипломатии МГИМО МИД России, специалист в области истории и теории дипломатии. Его основные научные интересы охватывают такие темы, как экономическая дипломатия, научная дипломатия, международное научнотехническое сотрудничество в контексте российской внешней политики, а также внешних связей ЕС. Окончил МГИМО МИД России. В 2016 г. получил ученую степень кандидата экономических наук.

Беседу вел С.М. Маркедонов, главный редактор журнала «Международная аналитика»
Association between clinical characteristics and pain relief in patients with axial spondyloarthritis treated with non-steroidal anti-inflammatory drugs
Authors: Deng Shiyi , He Yi , Deng Sisi , Sun Erwei , Li Li
Published: December 2021

Objectives: The aim of this study was to evaluate pain relief in axial spondyloarthritis (axSpA) patients treated with non-steroidal anti-inflammatory drugs (NSAIDs) and to investigate the relation of the demographic, clinical, and psychological characteristics with pain relief.

Patients and methods: Between February 2017 and December 2019, a total of 94 patients (61 males, 33 females; mean age: 28.3±8.1 years; range, 14 to 54 years) who were diagnosed with axSpA and treated with NSAIDs were included. The patients were assessed at baseline and at three months. A reduction of 30% in the Numeric Rating Scale (NRS) indicates a clinically meaningful improvement. The patients were divided into the relief group (≥30% improvement in NRS) and non-relief group (<30% improvement). Potential influential factors for pain relief such as neuropathic pain (NP), disease activity, function, pain catastrophizing, and pain self-efficacy were assessed. The relationship between patients’ characteristics and pain relief was analyzed.

Results: Seventy-two (76.6%) patients achieved pain relief. These patients had significantly higher baseline erythrocyte sedimentation rate, C-reactive protein, and lower percentage of NP. There was no significant difference between the two groups in function, pain catastrophizing, and pain self-efficacy. Multiple logistic regression analysis revealed that patients with NP were less likely to achieve pain relief (odds ratio [OR]: 3.531, 95% confidence interval [CI]: 1.155-10.789; p=0.027).

Conclusion: Pain relief is still insufficient in some axSpA patients, despite the administration of NSAIDs. The presence of NP is significantly associated with poor pain relief. Alternative medications instead of NSAIDs are needed to achieve optimal pain relief, when NP is diagnosed.
Validity and reliability of the Mini-Osteoarthritis Knee and Hip Quality of Life scale in Turkish population
Authors: Tuncay Duruöz Mehmet , Acer Kasman Sevtap , Hande Gezer Halise , Duruöz Evrim
Published: December 2021

Objectives: This study aims to investigate the validity and reliability of the Turkish version of the Mini-Osteoarthritis Knee and Hip Quality of Life (Mini-OAKHQoL) scale developed to assess the quality of life (QoL) in patients with knee and/or hip osteoarthritis.

Patients and methods: Between May 2018 and May 2020, a total of 83 patients (11 males, 72 females; mean age: 58.1±10.0 years; range, 39 to 81 years) with knee and/or hip osteoarthritis were included. Demographic, clinical, and survey data (Mini-OAKHQoL, Nottingham Health Profile, Short Form-36, Western Ontario and McMaster Universities Osteoarthritis Index, Lequesne Index, and Visual Analog Scale of pain intensity) were recorded. Missing data, floor effect, and ceiling effect were calculated. For reliability analysis, internal consistency and test-retest reliability were discovered. Face, content, convergent, and divergent validities were applied.

Results: Among the patients, 52 (62.65%) had knee osteoarthritis, 26 (31.32%) had hip osteoarthritis, and five (6.02%) had both. Mini-OAKHQoL had a good face and content validity. The average item completion rate was 96.9%, with the time needed to perform was about 4 min. None of the subscales of Mini-OAKHQoL presented floor or ceiling effect, with a good range of responses. The Cronbach alpha coefficients and intraclass correlation coefficient (ICC) analysis of the subscales ranged from 0.927 to 0.676 and 0.987 to 0.843, respectively. Regarding convergent validity, the physical activities, mental health, and pain subscales of Mini-OAKHQoL had moderate to high correlations with the topic-related subset of the other QoL surveys. There were no or weak correlations between Mini-OAKHQoL and non-QoL parameters, indicating its divergent validity.

Conclusion: The Turkish version of Mini-OAKHQoL is a valid, reliable, simple, practical, accurate, completable, comprehensive, and disease-specific self-report instrument to assess QoL in patients with knee and/or hip osteoarthritis.
Measuring the impact of an educational intervention in rheumatoid arthritis: An open-label, randomized trial
Authors: Michou Laëtitia , Julien Anne-Sophie , Witteman Holly O. , Légaré Jean , Ratelle Lucie , Godbout Alexandra , Tardif Johanne , Côté Suzanne , Boily Geneviève , Lui Rebecca , Ikic Alena , Trudeau Judith , Tremblay Jean-Luc , Fortin Isabelle , Bessette Louis , Chetaille Anne-Laure , Fortin Paul R
Published: December 2021

Objectives: This study aims to determine whether patients with active rheumatoid arthritis (RA), either starting on or changing biological or targeted synthetic disease-modifying antirheumatic drugs (DMARDs), demonstrate better self-management safety skills three months after receiving a multidisciplinary educational intervention compared to patients receiving usual care.

Patients and methods: Between October 2015 and October 2018 , this open-label, randomized-controlled trial included a total of 107 RA patients (27 males, 80 females; mean age: 60.2±10.4 years; range, 54 to 71 years) who were on treatment or in whom treatment was changed with a biological or targeted synthetic DMARD. The patients were randomized into two groups: Group 1 (n=57) received additional intervention with educational DVD and one teleconference session and Group 2 (n=55) received usual care and were offered the intervention at three months. All patients underwent a final visit at six months. At each visit, the patients completed the BioSecure questionnaire measuring the self-care safety skills, a behavioral intention questionnaire, and the Beliefs about Medicines Questionnaire (BMQ).

Results: No significant difference was observed in the Biosecure score at three months between the two groups (p=0.08). After pooling the first three-month data in Group 1 and the last three-month data in Group 2, the mean score of the BioSecure questionnaire increased to 7.10±0.92 in the group receiving educational intervention (p<0.0001). This increase was maintained at six months in Group 2 (p=0.88). The rate of appropriate behavioral intention increased over time (76% at baseline and 85% at six months for both groups). There was no significant change in the BMQ (p=0.44 to 0.84).

Conclusion: The development of an educational DVD followed by a teleconference seem to improve self-care safety skills of the patients in practical situations.
Serum lysyl oxidase concentration increases in long-standing systemic sclerosis: Can lysyl oxidase change over time?
Authors: Hassan Jokar Mohammad , Jafaripour Simin , Abdollahi Nafiseh , Nazemipour Maryam , Moradzadeh Maliheh , Ali Mansournia Mohammad
Published: December 2021

Objectives: This study aims to investigate the association of serum lysyl oxidase (LOX) levels with systemic sclerosis (SSc), to examine the relationship between LOX and disease onset, and to evaluate the probable effects of hyperlipidemia on the circulating levels of LOX among patients with SSc.

Patients and methods: Between May 2017 and November 2018, a total of 39 patients with SSc (2 males, 37 females; mean age: 46.6±12.3 years; range, 18 to 65 years) and 35 healthy controls (4 males, 31 females; mean age: 43.1±14.1 years; range, 18 to 65 years) were included. Serum LOX concentration was measured using the enzyme-linked immunoassay in triplicate.

Results: We found higher levels of serum LOX in patients with SSc compared to healthy controls. There was a significant relationship between serum LOX levels and disease onset. Patients with long-standing disease demonstrated increased levels of LOX in the blood compared to the recent-onset group. Hyperlipidemia did not have a significant effect on circulating levels of LOX. There was a significant negative correlation between LOX levels and modified Rodnan Skin Score in the subgroup of patients with skin involvement only and in patients without gastrointestinal involvement.

Conclusion: Our study findings show an increased level of LOX protein level in the blood of patients diagnosed with SSc. Hyperlipidemia seems not to affect the concentrations of LOX in the peripheral blood of patients with SSc.
Relationship between diet, oxidative stress, and inflammation in ankylosing spondylitis
Authors: Tel Adıgüzel Kübra , Gül Yurdakul Fatma , Seremet Kürklü Nilgün , Yaşar Evren , Bodur Hatice
Published: December 2021

Objectives: This study aims to investigate the relationship between disease activity, dietary phytochemical index (DPI), and serum total oxidant status (TOS) and total antioxidant status (TAS) in patients with ankylosing spondylitis (AS).

Patients and methods: Between August 2020 and January 2021, a total of 37 patients (23 males, 14 females; mean age: 39.3±9.4 years; range, 21 to 61 years) with AS and 36 age-, sex-, and body mass index-matched healthy individuals (24 males, 12 females; mean age: 37.9±8.9 years; range, 20 to 60 years) were included. Serum TAS (μmoLTroloxEq/L) and TOS (μmoL H2O2Eq/L) measurements were performed and the oxidative stress index (OSI) was calculated. Dietary evaluation was made from a one-day dietary record and DPI was calculated.

Results: Serum TAS level in AS patients was significantly lower than the healthy group (p=0.003). Serum TOS level was similar in both groups. The OSI of patients was significantly higher than the controls (p=0.035). The mean DPI, polyunsaturated fatty acid, n-3 fatty acid, and vitamin C intake of patients were significantly lower than controls (p=0.042, p=0.033, and p=0.022, respectively). A moderate positive correlation was found between the TAS level and DPI of the control group (r=0.352, p=0.035). According to medications, no significant difference was seen between the groups in terms of patients’ characteristics, DPI, and laboratory tests and there was no correlation between DPI, TAS, TOS, and OSI.

Conclusion: Lower DPI and lower n-3 fatty acid and vitamin C intake in patient group demonstrated that patients with AS should pay more attention to their diet to increase serum antioxidant status.
High prevalence of latent tuberculosis using the QuantiFERON-TB Gold Plus test in Takayasu arteritis
Authors: Luisa Souza Pedreira Ana , Pinheiro Leal Costa Rodrigo , Filipe Pitanga Silva Josenor , Barreto Santiago Mittermayer
Published: December 2021

Objectives: This study aims to investigate latent tuberculosis using the QuantiFERON-TB Gold Plus method in patients with Takayasu arteritis (TA).

Patients and methods: This case-control study included 22 patients with TA (3 males, 19 females; median age: 36.5 years; IQR, 32 to 50 years), 22 healthy individuals (3 males, 19 females; median age: 38.5 years; IQR, 32.5 to 50 years), and 66 patients with diffuse connective tissue diseases (DCTDs) (4 males, 62 females; median age: 41 years; IQR, 29.8 to 54 years). Two control groups were formed: (i) age- and sex-matched healthy individuals and (ii) patients with other DCTDs. Epidemiological data were collected, and the QFT-Plus test was performed. The QFT-plus positivity was compared among the groups.

Results: A higher prevalence of QFT-Plus positive cases was observed in the TA group (8/22) than in the healthy control group (1/22) (p=0.020) or in the group with other DCTDs (3/66) (p=0.001). There was a statistically significant difference in the past pulmonary tuberculosis prevalence between the TA and DCTD groups (p=0.013).

Conclusion: The prevalence of latent tuberculosis in TA patients (36.4%) was higher than that in both control groups and higher than the prevalence of latent tuberculosis among the general Brazilian population. Although a positive association was found, it is not possible to establish a direct cause-effect relationship. Given the increasing use of anti-cytokine therapies in TA, it is necessary to thoroughly screen patients with TA before initiating immunosuppressive therapy to avoid tuberculosis reactivation.
Is COVID-19 multisystem inflammatory syndrome a new variant of Kawasaki Disease?
Authors: Abu Hammour Khawla , Abu Farha Rana , Manaseer Qusai , Dawoud Tasnim , Abu Hammour Walid
Published: December 2021

Objectives: In this systematic review, we aimed to evaluate the clinical features, therapeutic options, and outcomes of children with multisystem inflammatory syndrome in children (MIS-C) and to investigate whether MIS-C is a new variant of Kawasaki disease.

Materials and methods: Adhering to PRISMA principles, we searched for eligible studies between December 2019 and June 2020 through the following databases: PubMed, ISI Web of Science, SCOPUS, and Science Direct. Studies including original data of patients aged <21 years with MIS-C and descriptions of clinical signs, laboratory or radiological investigations were selected.

Results: A total of 84 studies were identified, for which 48 were eligible for full screening and only 13 studies (n=657) met our inclusion criteria. More than 70% of patients with MIS-C tested positive for severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2). The most common symptoms were gastrointestinal (80 to 100%) and most patients presented with fever for >4 days. Mucocutaneous manifestations are similar to Kawasaki disease presented in up to 64% in some studies. Almost all patients had significant elevations in inflammatory markers, and up to 50 to 100% had elevated troponin suggesting myocardial damage. Intravenous immunoglobulin (IVIG) was administered to 60% of patients in 12 studies and 80 to 100% in five studies. Steroids were administered to 10 to 95% of patients. The overall mortality rate was 0.9%.

Conclusion: The temporal association between novel coronavirus disease 2019 (COVID-19) onset and Kawasaki-like disease and MIS-C suggests a causal link. Both syndromes have similar cascades of symptoms and hyperinflammation, which likely explain their response to the same immunomodulatory agents. However, it is unclear yet why some children appear more susceptible to develop MIS-C.
LncRNA cardiac autophagy inhibitory factor is downregulated in rheumatoid arthritis and suppresses the apoptosis of fibroblast-like synoviocytes by promoting the maturation of miRNA-20a
Authors: Xu Dongming , Lin Ling , Chen Zhen
Published: December 2021

Objectives: In this study, we aimed to investigate the effects of LncRNA cardiac autophagy inhibitory factor (CAIF) and miR-20a on the apoptosis of synovial cells in rheumatoid arthritis (RA) and the regulatory mechanism.

Patients and methods: Between May 2018 and March 2020, a total of 62 RA patients (24 males, 38 females; mean age: 55.2±4.9 years; range, 42 to 68 years) and 62 controls (24 males, 38 females; mean age: 55.3±4.8 years; range, 41 to 68 years) were included in this study. Plasma samples were collected from all participants. The expression levels of CAIF, mature miR-20a, and miR-20a precursor in these plasma samples were determined by reverse transcription-quantitative polymerase chain reaction (RT-qPCR). Correlations were analyzed using linear regression analysis. Overexpression of CAIF was achieved in human fibroblast-like synoviocytes (HFLSs) and the expression levels of mature miR-20a and miR-20a precursor were determined using RT-qPCR. Cell apoptosis was analyzed by cell apoptosis assay.

Results: The CAIF was downregulated in RA and positively correlated with the expression of mature miR-20a. In HFLSs, LPS treatment resulted in downregulation of both CAIF and miR-20a in a dose-dependent manner. In HFLSs, overexpression of CAIF did not affect the expression of miR-20a precursor, but upregulated the expression of mature miR-20a. Cell apoptosis analysis showed that overexpression of CAIF and miR-20a inhibited the apoptosis of HFLSs induced by LPS. The combination of overexpression of CAIF and miR-20a showed a stronger effect.

Conclusion: The CAIF may suppress the apoptosis of HFLSs in RA by promoting the maturation of miR-20a.
3B BASKI TEKNOLOJİSİ KULLANILARAK OTONOM SUALTI ARACI TASARIMI VE PROTOTİP ÜRETİMİ
Authors: KARAÇOR Mevlüt , DELİOGLU Bugrahan , ŞAHİN Cihan
Published: December 2021

Bu çalışmada 3B baskı teknolojisi kullanılarak otonom sualtı aracı (AUV) tasarımı ve uygulamasını gerçekleştirilmiştir. Dünyanın büyük bir bölümü denizler ve okyanuslardan oluşmaktadır. Bu gerçeğe rağmen sualtı araştırmaları kara ve hava ile karşılaştırıldığında geriden gelmektedir. Fakat son yıllarda dünyamızda ve ülkemizde sualtı araştırmaları önem kazanmaktadır. Özellikle sualtı maden, petrol ve doğalgaz yataklarına olan ilgiyle bu alandaki eksik daha çok hissedilmekte ve teknolojik çalışmalara ilgi daha da artmaktadır. Bu noktada en önemli ve en fazla ilgiyi sualtı robotları almaktadır. Yapılan bu çalışmada tüm bu ilgi ve ihtiyaç gereksinimleri ışığında, ilgili her alanda kullanılabilecek bir AUV prototipi gerçekleştirilmiştir. İmalatı gerçekleştirilen otonom sualtı aracı, hidrodinamik, sualtı sabit basınç ve dinamik basınç değişkenleri açısından değerlendirilerek kabiliyet yetenekleri arttırılırmıştır. Otonom sualtı robotunun kabuk tasarımı sualtında manevra yeteneği yüksek canlılar gözlemlenerek gerçekleştirilmiş ve HAD (Hesaplamalı Akışkanlar Dinamiği) analizleri yapılmıştır. Kabuk tasarımı ve imalatının gerçekleştirilmesinin ardından, tahrik sistemi ve elektronik donanımlar tamamlanarak otonom sualtı aracının fiziki yapısı tamamlanmıştır.
Aproximación del teletrabajo en el ámbito universitario
Authors: Brito-Cruz Teresa del Jesús , Lara-Gamboa Carmen Cecilia , Morales Diego Alicia Mariela , Sánchez May María del Carmen , Perez-Jaimes Alejandra Karina , Torres-Zapata Ángel Esteban
Published: December 2021

El Teletrabajo hoy en día ha adquirido mayor visibilidad en la aplicabilidad en los contextos organizacionales, incluyendo el ámbito educativo, trabajar virtualmente o a distancia es una nueva manera de trabajar y los beneficios de la aplicabilidad en las instituciones de educación superior en México cada vez poseen mayor alcance. El objetivo del presente estudio de investigación fue describir el estado actual del conocimiento del Teletrabajo en el ámbito universitario. Es un estudio documental descriptivo, mediante la revisión de artículos científicos utilizando el enunciado clave en español: “Teletrabajo en el ámbito universitario” en el aparato de búsqueda Google Académico. Los datos se registraron en una matriz de doble entrada, identificando la correspondencia entre objetivos, metodología, resultados y conclusiones. Los resultados de la revisión muestran suficiente evidencia para recomendar continuar el abordaje de este tema.
Eficiencia en el uso del agua y crecimiento en calabaza por el uso de poliacrilamida
Authors: Núñez-Ramírez Fidel , Robles Contreras Contreras Fabián , Vazquez Angulo Juan Carlos , Martínez-Varela Kenneth Jharym
Published: December 2021

Se realizó un estudio en plántulas del cultivo de calabaza (Cucurbita pepo L.), con el objetivo de conocer su crecimiento y desarrollo, así como la utilización de agua de riego por la aplicación de cuatro dosis de poliacrilamida (PAM; 0, 5, 10 y 20 g maceta-1) mezclada en sustrato. Durante el estudio, se midió el consumo de agua en cada uno de los tratamientos. Al final del estudio se midió el peso fresco y peso seco de las plantas; así mismo se midió el área foliar, la cantidad total de agua aplicada y la eficiencia en el uso del agua. Los resultados mostraron que después de once días de iniciados los tratamientos, se encontraron diferencias significativas en la utilización del agua por las plántulas (P < 0.05), siendo los tratamientos de 10 y 20 g de PAM maceta-1 los que conservaron más agua en el sustrato. Solo el peso fresco de la parte aérea presentó diferencias significativas a la aplicación de los tratamientos (P < 0.05). El área foliar no se afectó significativamente por los tratamientos aplicados (P > 0.05). Sin embargo, conforme se incrementó la dosis de PAM, se redujo la aplicación del agua de riego, resultando en una mayor eficiencia en el uso del agua por biomasa producida. Se concluyó que con la utilización PAM, es posible reducir el agua de riego a las plántulas de calabacita al tiempo que se mantiene el crecimiento.
BIJA, BIJABHAGA AND BIJABHAGA-AVAYAVA ASSOCIATED WITH ANUVANSHIKI
Authors: Mohini Mohini , Yadav Sanjay Kumar , Kumari Sunita
Published: December 2021

Ayurveda is one of the most ancient life sciences it is mentioned by acharyas that it is more ancient than man because it came earlier to earth. Being a life science there is description of how life came to origin, how to live life along with the description of various diseases under various disciplines. Here by Acharya Charak and Vriddha Vagbhatta- Bija, Bijabhaga and Bijabhaga-avayava is mention as three basic components of genetics, which are responsible for inheritance of various characteristics as well as for various diseases. The human genome project started in 1990 had aimed to identified human genetic coding of DNA, so that disease associated with genetic mutation or deletion can be prevented in their acute stage like cancer, leprosy, thalassemia, etc. In the same manner Acharyas also mention various diseases associated with bija, bijabhaga, bijabhaga-avayava dusti and transferred to next progeny. In this article we highlighted over the genetic defect of Secondary sexual development.
Keywords: Bija, Bijabhaga, Bijabhaga-avayava, dusti, Shukra, Shonita, etc.
A REVIEW ARTICLE - CONCEPT OF OLIGOMNIOSIS IN AYURVEDA
Authors: Kumar Geetha , Suseelan Indusree C
Published: December 2021

Introduction: The recent incidences of oligoamnios according to the prospective case control study 23 % prevalence among the three hundred eight antenatal ladies with singleton pregnancy between 34 and 41 weeks of gestation included in the study.
Aim and Objective: To understand the condition of Oligoamnios under the Ayurvedic perspective and to r eview the Ayurvedic classics and critically analyses the same. Materials & Methods: All Ayurvedic classic text authored by Brihatrayees and Laghutrayees, related journals, modern biomedical text and web were referred for r eview of literature. Literature Review: Oligoamniosis is characterized by less volume of liquor amnii (less than 2 00ml at 20-41st weeks of gestation), affecting the well-being and maturity of the growing fetus. The lubricating ac tion of liquor amnii is reduced, the free movements of the fetus affected and cause adhesion between the body part s and with the amniotic sac can be seen as complications. Discussion: Ayurvedic point of view oligo-hydramnios can be considered under the broad spectrum of jarayu dosha mentioned in Sarangadhara Samhitha. According to Acharya Sarangadhara, jarayu is the membranous covering of the fetus in its intra-uterine life while the liquor amnii secreted from amnion as ambu/ garbhodaka. Conclusion: From an Ayurveda viewpoint, oligoamnios can b e considered under the broad spectrum of ambupoornavyadhi or ulbakaroga characterized by hridroga (cardiac di sorder), akshepaka (convulsions), swasa (dysnoea), kasa (cough), chardi (vomiting) and jwara (fever) etc., disord ers and also all abnormalities of amnion such as unusual friability, amnionitis, cyst, amnion nodosum, amniotic ad hesions along with poly-hydramnios and oligo-hydramnios.
A CONCEPTUAL REVIEW ON PURISA (STOOL) PARIKSHA
Authors: Patel Ramnarayan , Kande Aradhana
Published: December 2021

In Ayurved; Astasthana pariksha is one of the important examinations to find the various causes behind diseases. In Ayurvedic text, different methods have been described for diagnosis of various aspect of disease, the Purisa pariksha (Stool examination) is one of them. Purisa pariksha is the main laboratory investigation tool which is necessary to diagnosis the disease described under samanya pariksha regarding the abnormalities in terms of col- or, odor, quality, consistency etc. In all ancient days, the identification of ama is used to be done by purisa parik- sha only. This review article aims to focus on the importance of Purisa pariksha. This conceptual study is helpful in the management of various progressive chronic diseases.
Keywords: Astasthana pariksha, Mala pariksha, Purisa pariksha, Stool.
EFFECTS OF VYAYAM AND NASYA IN THE MANAGEMENT OF HYPOTHYROIDISM: CONCEPTUAL REVIEW
Authors: Jain Shalu , Shukla Umesh
Published: December 2021

Lifestyle is accountable for the origin of a diseases; it is a very ancient and famous theory in Ayurveda. Nowa- days there has been a profound change in the dietary habits and lifestyle of human being due to modernization. Deleterious eating habits, along with sedentary lifestyle, cause various ailments including metabolic disorders. Thyroid gland is a key part of the human endocrine system and works together with nervous and immune system and it regulates metabolism by producing and secreting hormones into blood. Inadequate production of thyroid hormone is considered as hypothyroidism. Auto immunity plays a key role in the etiology of hypothyroidism. Global incidence of hypothyroidism is rising rapidly, and it is posing a major health challenge in both developing as well as developed world. Hypothyroidisms influence the standard of life of individuals, despite many progress- es the modern management of hypothyroidism remains disappointing. Looking into the pathogenesis and compli- cation of hypothyroidism, it requires a systemic and radical therapy for which ayurveda may provide a ray of hope through panchakarma, there is abnormality of Jatharagni and Dhatwagni, urdhvajatrugata sthan along with ab- normality of Kapha and Vata Dosha as well as Kaphamedo-Avrita Vata. Thus, the line of treatment involves Deepana, Pachana, Srotoshodhana, Nasya, Vyayam and Kapha vata shaman.
Keywords: Hypothyroidism, Agnimandya, Metabolism, Nasya, Vyayam.
IMPACT OF WORKPLACE BULLYING ON THE ATTITUDE AND PERFORMANCE OF UNIVERSITY TEACHERS
Authors: Khalid Muhammad Naveed , Iqbal Asif , Shafiq Farah
Published: December 2021

Workplace Bullying is a form of cognitive extremism at work. It revealed in misbehavior, activities, and verbal remarks, often deceptive, used to destabilize the person. This behavior results in mental surrender. Bullying leads to the victim’s withdrawal from an institute. It often happens in the form of deleterious remarks, unjustified blame, and submitted abuses. It destabilizes the freedom of expression, isolate the victims, querying them personally and professionally, and deny their access to resources to perform their task. It threatens the victims’ health and make them insecure. The current study is designed to investigate the impact of workplace bullying on the attitude and performance of university teachers. One hundred teachers (38 males and 62 females) were selected randomly from a total of 700 faculty members. Data were collected with the help of self-developed instrument, Teachers Workplace Bullying Attitude and Performance Survey (TWBAPS) with Cronbach Alpha reliability .965. Mean, standard deviation, ANOVA and t-test were applied to analyze the results. There was a significant difference between male and female teachers’ attitude and performance. Female teachers were victimized by their colleagues and heads. They showed a more aggressive attitude and low performance. Male teachers showed more violent behaviors than females. It is recommended to stabilize the academic environment at university level by discouraging the negative attitude among faculty members.
Key words: Academic bullying, aggressive attitude, teachers’ performance
Criza cunoașterii de sine
Authors: Gonța Victoria , Roșcan Elena
Published: December 2021

This article addresses the subject of self-knowledge as a necessity for the personaldevelopment process in achieving the own life ideal. We have set out to consider whether the self-knowledge process is an approach that occurs naturally, as a trend towards the integrity of a human being or synergy with the surrounding world, up to the union with transcendence or a preoccupation, a conscious, eff ervescent search, that requires interest and eff ort in developing the potentialities until the fulfi lment of the achieved self at the highest level. Is this process a component part of motivation in achieving success within profession, our relations with others or our development actions, from intuitive structures of individual thinking and primary conduct of group and society integration, to elements of metacognition, creativity and society integration through high moral values?
YILDIZ RAMAZANOĞLU’NUN CAM KENARI ADLI HİKÂYE KİTABINDA MÜLTECİLER
Authors: DOĞAN Alpay Doğan
Published: December 2021

Yıldız Ramazanoğlu, 1958’de Ankara’da dünyaya gelir. Ankara Lisesi ve Hacettepe Üniversitesi Eczacılık Fakültesi’ni bitirir. Öğrencilik yıllarında yazmaya başlar; süreli yayınlarda dene¬me ve hikâyeler yazar. Sivil toplum örgütlerinde çalışır. Türkiye, Avrupa, Amerika ve Orta Doğu’da kadın zirvelerine katılır, tebliğler sunar. Roman, gezi, inceleme, deneme türlerinde yayımlanmış kitapları vardır. Sekiz hikâye kitabı yayımlanır. Son hikâye kitabı Cam Kenarı 2021’de yayımlanır. Yıldız Ramazanoğlu’nun hikâye coğrafyası Türkiye dışına da açılır. Cam Kenarı adlı hikâye kitabında da farklı ülkelerden Türkiye’ye gelmiş insanların hikâyelerine tanık oluruz. Cam Kenarı adlı eseri “Mülteciler” ve “Mülteci Olmayanlar” adlarıyla iki bölüme ayrılır. Bu yazıda önce Yıldız Ramazanoğlu’nun önceki hikâye kitaplarında yer alan bir kısmı mülteci Türkiyeli olmayan hikâye kişilerine değinilmiştir. Bunların bir kısmı mültecidir. Ardından Cam Kenarı’nda yer alan “mülteci” konulu hikâyeler yorumlanmıştır. Ramazanoğlu, mültecilerin çoğunun zor şartlarda yaşadıklarını gösterir. Yazarın hikayeleri okurda mültecilere karşı “empati yeteneğinin gelişmesine yardım etmek ister” diyebiliriz.
General Health, Dental Status & Perceived Dental Treatment Needs of An Elderly Population in India
Authors: Utkarsh Shishodia  , Sukreeti Krishan  , Subham Sharma  , Vaibhav Anand  , Mohit Kaushik
Published: December 2021

Objectives: This pilot study determined the general and dental health status; perceived medical and dental treatment needs of an elderly population dwelling in residential homes in Himachal Pradesh (India).Method: Subjects were chosen from OPD of Department of Prosthodontics & Implantology, Himachal institute of dental sciences, Paonta sahib, (H.P) between April 2020 – April 2021. (N=133, female: 71 and male: 62) were involved in this study. A detailed questionnaire was prepared and dental examinations were conducted. Information was collected related to age, education levels, financial status, current physical functional status, general health, mental health, previous dental history, current dental status, oral hygiene practices and denture hygiene of these elderly people. The prevalence of edentulism, the presence and type of dental prostheses, dental and denture status and denture cleanliness were further evaluated.Results: The three most prevalent reported general health problems were associated with Genito-urinary problems (24%) followed by cardiovascular (18%) and respiratory problems (14%) varying significantly between genders, with males suffering more from cardiovascular problems than females (p < 0.05). Females showed significantly higher gastrointestinal and orthopaedic problems than males (p < 0.05). Females were more frequently edentulous than males but denture hygiene was significantly better in females than in males (p < 0.05). Brushing frequency did not significantly increase denture hygiene (p = 0.6). More than one-third of the subjects had not been to the dentist within the previous 5–10 years, mainly due to lack of demand, followed by the cost of the dental care and fear. More than two-thirds of denture-wearing subjects wore their dentures only during eating.
Implementation of Reciprocal Teaching Strategies: Improving Reading Skills and Academic Performance of Secondary Students
Authors: Dadabhoy Kiran , Dadabhoy Marium
Published: December 2021

Proficiency in reading comprehension is very important especially for secondary English language students. In this mixed methods study, the research proven methodological intervention “reciprocal teaching” is introduced to improve the reading skills and academic performance of 30 secondary students of grade 11.  Reciprocal teaching is a scaffold dialogue technique that is built upon four strategies which competent readers use to understand text namely predicting, questioning, clarifying and summarizing. The four strategies of reciprocal teaching were each part of the four interrelated cycles that comprised the related activities implemented during the intervention. A general plan inclusive of activities, teaching resources, observation schedules, checklists and assessments was constructed and used for data collection. When the scores of pre and post assessments were compared using paired samples t test, they showed a significant amount of improvement in grades of students as well as their ability to effectively understand the text. The outcomes proved reciprocal teaching to be a significant technique for improving reading comprehension skills and academic performance. In addition, the implication for teachers who teach reading comprehension is that through modeling and implementation of the reciprocal strategies like predicting, clarifying, questioning and summarizing they can enhance the academic performance of students.