bluuebunny/crossref_metadata_2025 huggingface dataset:
Correction: Corrigendum: Graphene Oxide promotes embryonic stem cell differentiation to haematopoietic lineage
Authors: Garcia-Alegria Eva , Iliut Maria , Stefanska Monika , Silva Claudio , Heeg Sebastian , Kimber Susan J. , Kouskoff Valerie , Lacaud Georges , Vijayaraghavan Aravind , Batta Kiran
Published: July 2016

Scientific Reports 6: Article number: 25917; published online: 20 May 2016; updated: 04 July 2016 The original version of this Article contained a typographical error in the spelling of the author Maria Iliut which was incorrectly given as Maria Iluit. This has now been corrected in the PDF and HTMLversions of the Article.
The minimization of mechanical work in vibrated granular matter
Authors: Clewett James P. D. , Wade Jack , Bowley R. M. , Herminghaus Stephan , Swift Michael R. , Mazza Marco G.
Published: July 2016

Experiments and computer simulations are carried out to investigate phase separation in a granular gas under vibration. The densities of the dilute and the dense phase are found to follow a lever rule and obey an equation of state. Here we show that the Maxwell equal-areas construction predicts the coexisting pressure and binodal densities remarkably well, even though the system is far from thermal equilibrium. This construction can be linked to the minimization of mechanical work associated with density fluctuations without invoking any concept related to equilibrium-like free energies.
Habitat use of bats in relation to wind turbines revealed by GPS tracking
Authors: Roeleke Manuel , Blohm Torsten , Kramer-Schadt Stephanie , Yovel Yossi , Voigt Christian C.
Published: July 2016

Worldwide, many countries aim at countering global climate change by promoting renewable energy. Yet, recent studies highlight that so-called green energy, such as wind energy, may come at environmental costs, for example when wind turbines kill birds and bats. Using miniaturized GPS loggers, we studied how an open-space foraging bat with high collision risk with wind turbines, the common noctule Nyctalus noctula (Schreber, 1774), interacts with wind turbines. We compared actual flight trajectories to correlated random walks to identify habitat variables explaining the movements of bats. Both sexes preferred wetlands but used conventionally managed cropland less than expected based on availability. During midsummer, females traversed the land on relatively long flight paths and repeatedly came close to wind turbines. Their flight heights above ground suggested a high risk of colliding with wind turbines. In contrast, males recorded in early summer commuted straight between roosts and foraging areas and overall flew lower than the operating range of most turbine blades, suggesting a lower collision risk. Flight heights of bats suggest that during summer the risk of collision with wind turbines was high for most studied bats at the majority of currently installed wind turbines. For siting of wind parks, preferred bat habitats and commuting routes should be identified and avoided.
Effects of landscape anthropization on mosquito community composition and abundance
Authors: Ferraguti Martina , Martínez-de la Puente Josué , Roiz David , Ruiz Santiago , Soriguer Ramón , Figuerola Jordi
Published: July 2016

Anthropogenic landscape transformation has an important effect on vector-borne pathogen transmission. However, the effects of urbanization on mosquito communities are still only poorly known. Here, we evaluate how land-use characteristics are related to the abundance and community composition of mosquitoes in an area with endemic circulation of numerous mosquito-borne pathogens. We collected 340 829 female mosquitoes belonging to 13 species at 45 localities spatially grouped in 15 trios formed by 1 urban, 1 rural and 1 natural area. Mosquito abundance and species richness were greater in natural and rural areas than in urban areas. Environmental factors including land use, vegetation and hydrological characteristics were related to mosquito abundance and community composition. Given the differing competences of each species in pathogen transmission, these results provide valuable information on the transmission potential of mosquito-borne pathogens that will be of great use in public and animal health management by allowing, for instance, the identification of the priority areas for pathogen surveillance and vector control.
Programmed activation of cancer cell apoptosis: A tumor-targeted phototherapeutic topoisomerase I inhibitor
Authors: Shin Weon Sup , Han Jiyou , Kumar Rajesh , Lee Gyung Gyu , Sessler Jonathan L. , Kim Jong-Hoon , Kim Jong Seung
Published: July 2016

We report here a tumor-targeting masked phototherapeutic agent 1 (PT-1). This system contains SN-38—a prodrug of the topoisomerase I inhibitor irinotecan. Topoisomerase I is a vital enzyme that controls DNA topology during replication, transcription, and recombination. An elevated level of topoisomerase I is found in many carcinomas, making it an attractive target for the development of effective anticancer drugs. In addition, PT-1 contains both a photo-triggered moiety (nitrovanillin) and a cancer targeting unit (biotin). Upon light activation in cancer cells, PT-1 interferes with DNA re-ligation, diminishes the expression of topoisomerase I, and enhances the expression of inter alia mitochondrial apoptotic genes, death receptors, and caspase enzymes, inducing DNA damage and eventually leading to apoptosis. In vitro and in vivo studies showed significant inhibition of cancer growth and the hybrid system PT-1 thus shows promise as a programmed photo-therapeutic (“phototheranostic”).
Human neural stem cell-induced endothelial morphogenesis requires autocrine/paracrine and juxtacrine signaling
Authors: Chou Chung-Hsing , Modo Michel
Published: July 2016

Transplanted neural stem cells (NSC) interact with the host brain microenvironment. A neovascularization is commonly observed in the vicinity of the cell deposit, which is correlated with behavioral improvements. To elucidate the signaling mechanisms between human NSCs and endothelial cells (ECs), these were cocultured in an in vitro model in which NSC-induced endothelial morphogenesis produced a neurovascular environment. Soluble (autocrine/paracrine) and contact–mediated (juxtacrine) signaling molecules were evaluated for two conditionally immortalized fetal NSC lines derived from the cortical anlage (CTXOE03) and ganglionic eminence (STROC05), as well as an adult EC line (D3) derived from the cerebral microvasculature of a hippocampal biopsy. STROC05 were 4 times as efficient to induce endothelial morphogenesis compared to CTXOE03. The cascade of reciprocal interactions between NSCs and ECs in this process was determined by quantifying soluble factors, receptor mapping and immunocytochemistry for extracellular matrix molecules. The mechanistic significance of these was further evaluated by pharmacological blockade. The sequential cell-specific regulation of autocrine/paracrine and juxtacrine signaling accounted for the differential efficiency of NSCs to induce endothelial morphogenesis. These in vitro studies shed new light on the reciprocal interactions between NSCs and ECs, which are pivotal for our mechanistic understanding of the efficacy of NSC transplantation.
Monoclonal antibody with conformational specificity for a toxic conformer of amyloid β42 and its application toward the Alzheimer’s disease diagnosis
Authors: Murakami Kazuma , Tokuda Maki , Suzuki Takashi , Irie Yumi , Hanaki Mizuho , Izuo Naotaka , Monobe Yoko , Akagi Ken-ichi , Ishii Ryotaro , Tatebe Harutsugu , Tokuda Takahiko , Maeda Masahiro , Kume Toshiaki , Shimizu Takahiko , Irie Kazuhiro
Published: July 2016

Amyloid β-protein (Aβ42) oligomerization is an early event in Alzheimer’s disease (AD). Current diagnostic methods using sequence-specific antibodies against less toxic fibrillar and monomeric Aβ42 run the risk of overdiagnosis. Hence, conformation-specific antibodies against neurotoxic Aβ42 oligomers have garnered much attention for developing more accurate diagnostics. Antibody 24B3, highly specific for the toxic Aβ42 conformer that has a turn at Glu22 and Asp23, recognizes a putative Aβ42 dimer, which forms stable and neurotoxic oligomers more potently than the monomer. 24B3 significantly rescues Aβ42-induced neurotoxicity, whereas sequence-specific antibodies such as 4G8 and 82E1, which recognizes the N-terminus, do not. The ratio of toxic to total Aβ42 in the cerebrospinal fluid of AD patients is significantly higher than in control subjects as measured by sandwich ELISA using antibodies 24B3 and 82E1. Thus, 24B3 may be useful for AD diagnosis and therapy.
Integrated Electrowetting Nanoinjector for Single Cell Transfection
Authors: Shekaramiz Elaheh , Varadarajalu Ganeshkumar , Day Philip J. , Wickramasinghe H. Kumar
Published: July 2016

Single cell transfection techniques are essential to understand the heterogeneity between cells. We have developed an integrated electrowetting nanoinjector (INENI) to transfect single cells. The high transfection efficiency, controlled dosage delivery and ease of INENI fabrication promote the widespread application of the INENI in cell transfection assays.
Mechanism of sodium chloride in promoting reduction of high-magnesium low-nickel oxide ore
Authors: Zhou Shiwei , Wei Yonggang , Li Bo , Wang Hua , Ma Baozhong , Wang Chengyan
Published: July 2016

Sodium chloride has been proved that it is an effective promoter for the reduction of high-magnesium, low-nickel oxide ore. The aim of current work is to clarify the promotion behavior of sodium chloride in the roasting reduction process. The influence of moisture on the reduction of ore in the presence of sodium chloride is studied to get clear comprehension of promotion process. In the presence of moisture, the HCl is produced by pyrohydrolysis of sodium chloride for chlorinating nickel and iron oxides, moreover, interactions between metallic oxides and sodium chloride are also a way for chlorination at high temperature (>802 °C); subsequently, the metal chloride would be reduced by reductant. In the absence of moisture, the magnetic separation results show that the recoveries of iron and nickel have a significant increase; moreover, olivine structure would be destroyed gradually with the increase of roasting temperature in the action of sodium chloride and the sodium chloride existed in high-magnesium, low-nickel oxide ore could make the NiO isolate from NiO-bearing minerals. The NiO reacts with Fe2O3 at high temperature to form NiFe2O4, which is conductive to the formation of Ni-Fe alloy during the reduction process.
New insights in Microbial Fuel Cells: novel solid phase anolyte
Authors: Tommasi Tonia , Salvador Gian Paolo , Quaglio Marzia
Published: July 2016

For the development of long lasting portable microbial fuel cells (MFCs) new strategies are necessary to overcome critical issues such as hydraulic pump system and the biochemical substrate retrieval overtime to sustain bacteria metabolism. The present work proposes the use of a synthetic solid anolyte (SSA), constituted by agar, carbonaceous and nitrogen sources dissolved into diluted seawater. Results of a month-test showed the potential of the new SSA-MFC as a long lasting low energy consuming system.
Factors favoring regain of the lost vertical spinal height through posterior spinal fusion in adolescent idiopathic scoliosis
Authors: Shi Benlong , Mao Saihu , Xu Leilei , Sun Xu , Liu Zhen , Zhu Zezhang , Lam Tsz Ping , Cheng Jack CY , Ng Bobby , Qiu Yong
Published: July 2016

Height gain is a common beneficial consequence following correction surgery in adolescent idiopathic scoliosis (AIS), yet little is known concerning factors favoring regain of the lost vertical spinal height (SH) through posterior spinal fusion. A consecutive series of AIS patients from February 2013 to August 2015 were reviewed. Surgical changes in SH (ΔSH), as well as the multiple coronal and sagittal deformity parameters were measured and correlated. Factors associated with ΔSH were identified through Pearson correlation analysis and multivariate regression analysis. A total of 172 single curve and 104 double curve patients were reviewed. The ΔSH averaged 2.5 ± 0.9 cm in single curve group and 2.9 ± 1.0 cm in double curve group. The multivariate regression analysis revealed the following pre-operative variables contributed significantly to ΔSH: pre-op Cobb angle, pre-op TK (single curve group only), pre-op GK (double curve group only) and pre-op LL (double curve group only) (p < 0.05). Thus change in height (in cm) = 0.044 × (pre-op Cobb angle) + 0.012 × (pre-op TK) (Single curve, adjusted R2 = 0.549) or 0.923 + 0.021 × (pre-op Cobb angle1) + 0.028 × (pre-op Cobb angle2) + 0.015 × (pre-op GK)-0.012 × (pre-op LL) (Double curve, adjusted R2 = 0.563). Severer pre-operative coronal Cobb angle and greater sagittal curves were beneficial factors favoring more contribution to the surgical lengthening effect in vertical spinal height in AIS.
VirusMapper: open-source nanoscale mapping of viral architecture through super-resolution microscopy
Authors: Gray Robert D. M. , Beerli Corina , Pereira Pedro Matos , Scherer Kathrin Maria , Samolej Jerzy , Bleck Christopher Karl Ernst , Mercer Jason , Henriques Ricardo
Published: July 2016

The nanoscale molecular assembly of mammalian viruses during their infectious life cycle remains poorly understood. Their small dimensions, generally bellow the 300nm diffraction limit of light microscopes, has limited most imaging studies to electron microscopy. The recent development of super-resolution (SR) light microscopy now allows the visualisation of viral structures at resolutions of tens of nanometers. In addition, these techniques provide the added benefit of molecular specific labelling and the capacity to investigate viral structural dynamics using live-cell microscopy. However, there is a lack of robust analytical tools that allow for precise mapping of viral structure within the setting of infection. Here we present an open-source analytical framework that combines super-resolution imaging and naïve single-particle analysis to generate unbiased molecular models. This tool, VirusMapper, is a high-throughput, user-friendly, ImageJ-based software package allowing for automatic statistical mapping of conserved multi-molecular structures, such as viral substructures or intact viruses. We demonstrate the usability of VirusMapper by applying it to SIM and STED images of vaccinia virus in isolation and when engaged with host cells. VirusMapper allows for the generation of accurate, high-content, molecular specific virion models and detection of nanoscale changes in viral architecture.
Topical and Targeted Delivery of siRNAs to Melanoma Cells Using a Fusion Peptide Carrier
Authors: Ruan Renquan , Chen Ming , Sun Sijie , Wei Pengfei , Zou Lili , Liu Jing , Gao Dayong , Wen Longping , Ding Weiping
Published: July 2016

Topical application of siRNAs through the skin is a potentially effective strategy for the treatment of melanoma tumors. In this study, we designed a new and safe fusion peptide carrier SPACE-EGF to improve the skin and cell penetration function of the siRNAs and their targeting ability to B16 cells, such that the apoptosis of B16 cells can be induced. The results show that the carrier is stable and less toxic. The EGF motif does not affect the skin and cell penetration function of the SPACE. Because EGF can strongly bind EGFR, which is overexpressed in cancer cells, the targeting ability of the SPACE-EGF-siRNA complex is increased. In vitro experiments indicate that GAPDH siRNAs conjugated with SPACE-EGF can significantly reduce the GAPDH concentration in B16 cells and c-Myc siRNAs can cause the gene silencing of c-Myc and thus the apoptosis of cells. In vivo experiments show that the topical application of c-Myc siRNAs delivered by SPACE-EGF through the skin can significantly inhibit the growth of melanoma tumors. This work may provide insight into the development of new transdermal drug carriers to treat a variety of skin disorders.
RNA is an Adjuvanticity Mediator for the Lipid-Based Mucosal Adjuvant, Endocine
Authors: Hayashi Masayuki , Aoshi Taiki , Ozasa Koji , Kusakabe Takato , Momota Masatoshi , Haseda Yasunari , Kobari Shingo , Kuroda Etsushi , Kobiyama Kouji , Coban Cevayir , Ishii Ken J.
Published: July 2016

Nasal vaccination has the potential to elicit systemic and mucosal immunity against pathogens. However, split and subunit vaccines lack potency at stimulating mucosal immunity, and an adjuvant is indispensable for eliciting potent mucosal immune response to nasal vaccines. Endocine, a lipid-based mucosal adjuvant, potentiates both systemic and mucosal immune responses. Although Endocine has shown efficacy and tolerability in animal and clinical studies, its mechanism of action remains unknown. It has been reported recently that endogenous danger signals are essential for the effects of some adjuvants such as alum or MF59. However, the contribution of danger signals to the adjuvanticity of Endocine has not been explored. Here, we show that RNA is likely to be an important mediator for the adjuvanticity of Endocine. Administration of Endocine generated nucleic acids release, and activated dendritic cells (DCs) in draining lymph nodes in vivo. These results suggest the possibility that Endocine indirectly activates DCs via damage-associated molecular patterns. Moreover, the adjuvanticity of Endocine disappeared in mice lacking TANK-binding kinase 1 (Tbk1), which is a downstream molecule of nucleic acid sensing signal pathway. Furthermore, co-administration of RNase A reduced the adjuvanticity of Endocine. These data suggest that RNA is important for the adjuvanticity of Endocine.
Comparative Study of Carbon Materials Synthesized “Greenly” for 2-CP Removal
Authors: Ma Ying , Lu Nan , Lu Ying , Guan Jiu-nian , Qu Jiao , Liu Hai-yang , Cong Qiao , Yuan Xing
Published: July 2016

Carbon nanotubes (CNTs), graphene (GA) and carbon nanospheres (CNSs) were prepared respectively using grass (Festucaarundinace) as the sole carbon resource by solvothermal method and characterized as adsorbent and photocatalyst for 2-chlorophenol (2-CP) removal in water. With H2O2/HNO3/H2SO4, the CNTs were firstly produced from grass (Festucaarundinace) at 300 °C by hydrolysis and oxidization, the CNTs were secondly opened to form the GA by oxidization at 400 °C and the GA was lastly rolled-up to form the CNSs by oxidization at 500 °C. All adsorption equilibration of the CNTs, GA and CNSs for 2-CP were achieved within 120 min and 60.35%, 20.12% and 76.22% of 2-CP (5 mg L−1, pH = 6.3) were adsorbed, respectively. Furthermore, the high removal rates of 2-CP were about 88.23%, 92.90% and 79.64% by the CNTs, GA and CNSs, after 120 min adsorption and 160 min irradiation. On the basis of these results, the CNSs were suitable for removal 2-CP as adsorbent and the GA was suitable as photocatalyst. The photooxidation of 2-CP was mainly initiated by O2·− or ·OH which was generated from the combine with simulated sunlight and the CNTs or GA, respectively. However, the CNTs was not suitable for removal 2-CP owing to the increasing toxicity.
A Combinatorial Algorithm for Microbial Consortia Synthetic Design
Authors: Julien-Laferrière Alice , Bulteau Laurent , Parrot Delphine , Marchetti-Spaccamela Alberto , Stougie Leen , Vinga Susana , Mary Arnaud , Sagot Marie-France
Published: July 2016

Synthetic biology has boomed since the early 2000s when it started being shown that it was possible to efficiently synthetize compounds of interest in a much more rapid and effective way by using other organisms than those naturally producing them. However, to thus engineer a single organism, often a microbe, to optimise one or a collection of metabolic tasks may lead to difficulties when attempting to obtain a production system that is efficient, or to avoid toxic effects for the recruited microorganism. The idea of using instead a microbial consortium has thus started being developed in the last decade. This was motivated by the fact that such consortia may perform more complicated functions than could single populations and be more robust to environmental fluctuations. Success is however not always guaranteed. In particular, establishing which consortium is best for the production of a given compound or set thereof remains a great challenge. This is the problem we address in this paper. We thus introduce an initial model and a method that enable to propose a consortium to synthetically produce compounds that are either exogenous to it, or are endogenous but where interaction among the species in the consortium could improve the production line.
Determination of nicotine in tobacco products based on mussel-inspired reduced graphene oxide-supported gold nanoparticles
Authors: Jing Yanqiu , Yuan Xiuxiu , Yuan Qiu , He Kuanxin , Liu Yingjie , Lu Ping , Li Huaiqi , Li Bin , Zhan Hui , Li Guangliang
Published: July 2016

Polydopamine functionalized reduced graphene oxide-gold nanoparticle (PDA-RGO/Au) nanocomposites were successfully prepared by a simple and mild procedure. The PDA-RGO/Au nanocomposite is successfully formed in an aqueous buffer solution (pH 8.5) without using any reducing agent. FTIR confirmed the successful coating of PDA and informed the reduction of the surface functional groups of GO. The formation of reduced GO and Au NPs was further evidenced by UV-Vis and X-ray diffraction spectroscopy. This method is environmentally friendly and highly beneficial for the mass production of graphene-noble metal based nanocomposite. The as prepared PDA-RGO/Au nanocomposite could greatly enhance the electrochemical oxidation of nicotine. We fabricated an electrochemical nicotine sensor based on the prepared PDA-RGO/Au nanocomposite. The proposed nicotine sensor showed a wide detection range from 0.05 to 500 μM with a low detection limit of 0.015 μM. Moreover, the proposed nicotine sensor was also successfully applied for determination nicotine content in tobacco products.
The different effects of twin boundary and grain boundary on reducing tension-compression yield asymmetry of Mg alloys
Authors: Yu Huihui , Xin Yunchang , Chapuis Adrien , Huang Xiaoxu , Xin Renlong , Liu Qing
Published: July 2016

In the present study, a coarse grained AZ31 plate was refined by "Equation missing" twin boundaries (TBs) and grain boundaries (GBs), respectively. A comparative study about the different effects of grain refinements by GBs and by TBs on tension-compression yield asymmetry was performed. Our results show that both the refinements by GBs and by TBs increase the tensile and compressive yield strengths, but to a different degree. "Equation missing" TBs are more effective to harden "Equation missing" twinning, but yield a lower strengthening against prismatic  slip and a much lower tension-compression yield asymmetry is thus obtained. Both the differences in boundary coherence and misorientation between GBs and TBs affect the hardening. The misorientation of TBs provides a lower geometric compatibility factor (a higher hardening) for both prismatic  slip and "Equation missing" twinning than that of GBs, which in detail is the result of the much higher angle between c-axes of the two sides of TBs (about 86°) than GBs (0–50°). It is found that, for hardening of prismatic  slip, boundary coherence plays a more important role than misorientation. With regard to "Equation missing" twinning, the different misorientation of TBs from GBs mainly accounts for their different hardening effects.
Defective regulation of POMC precedes hypothalamic inflammation in diet-induced obesity
Authors: Souza Gabriela F. P. , Solon Carina , Nascimento Lucas F. , De-Lima-Junior Jose C. , Nogueira Guilherme , Moura Rodrigo , Rocha Guilherme Z. , Fioravante Milena , Bobbo Vanessa , Morari Joseane , Razolli Daniela , Araujo Eliana P. , Velloso Licio A.
Published: July 2016

Obesity is the result of a long-term positive energy balance in which caloric intake overrides energy expenditure. This anabolic state results from the defective activity of hypothalamic neurons involved in the sensing and response to adiposity. However, it is currently unknown what the earliest obesity-linked hypothalamic defect is and how it orchestrates the energy imbalance present in obesity. Using an outbred model of diet-induced obesity we show that defective regulation of hypothalamic POMC is the earliest marker distinguishing obesity-prone from obesity-resistant mice. The early inhibition of hypothalamic POMC was sufficient to transform obesity-resistant in obesity-prone mice. In addition, the post-prandial change in the blood level of β-endorphin, a POMC-derived peptide, correlates with body mass gain in rodents and humans. Taken together, these results suggest that defective regulation of POMC expression, which leads to a change of β-endorphin levels, is the earliest hypothalamic defect leading to obesity.
Predictive chromatography of peptides and proteins as a complementary tool for proteomics
Authors: Tarasova Irina A. , Masselon Christophe D. , Gorshkov Alexander V. , Gorshkov Mikhail V.
Published: July 2016

In the last couple of decades, considerable effort has been focused on developing methods for quantitative and qualitative proteome characterization.
In solution SERS sensing using mesoporous silica-coated gold nanorods
Authors: Gao Zhe , Burrows Nathan D. , Valley Nicholas A. , Schatz George C. , Murphy Catherine J. , Haynes Christy L.
Published: July 2016

Mesoporous silica-coated gold nanorods (AuNR@MS) act as a colloidally stable Raman sensing platform with a built-in analyte size cutoff.
Highly sensitive and reproducible silicon-based surface-enhanced Raman scattering sensors for real applications
Authors: Wang Houyu , Jiang Xiangxu , He Yao
Published: July 2016

During the past few decades, thanks to silicon nanomaterials’ outstanding properties, different dimensional silicon nanostructures have been employed for designing and fabricating high-performance surface-enhanced Raman scattering (SERS) sensors for chemical and biological detection.
Use of electrospinning and dynamic air focusing to create three-dimensional cell culture scaffolds in microfluidic devices
Authors: Chen Chengpeng , Mehl Benjamin T. , Sell Scott A. , Martin R. Scott
Published: July 2016

An air focusing technique was used to directly electrospin fibers into fully sealed microfluidic devices for 3D cell culture.
Use of conducting polymers to facilitate neurite branching in schizophrenia-related neuronal development
Authors: Stewart Elise M. , Wu Zhixiang , Huang Xu Feng , Kapsa Robert M. I. , Wallace Gordon G.
Published: July 2016

Schizophrenia (SCZ) is a debilitating mental disorder which results in high healthcare and loss of productivity costs to society.
Sensitive proton-detected solid-state NMR spectroscopy of large proteins with selective CH3labelling: application to the 50S ribosome subunit
Authors: Kurauskas Vilius , Crublet Elodie , Macek Pavel , Kerfah Rime , Gauto Diego F. , Boisbouvier Jérôme , Schanda Paul
Published: July 2016

CH3methyl labelling provides improved sensitivity in methyl-directed 1H solid-state NMR spectroscopy, compared to previously employed CHD2, opening possibilities to study very large proteins where sensitivity is often limited.
Anion recognition by a bidentate chalcogen bond donor
Authors: Garrett Graham E. , Carrera Elisa I. , Seferos Dwight S. , Taylor Mark S.
Published: July 2016

An ethynylene-linked bis(tellurophene) acts as an anion receptor through bidentate chalcogen bonding interactions.
Evidence of double layer/capacitive charging in carbon nanomaterial-based solid contact polymeric ion-selective electrodes
Authors: Cuartero Maria , Bishop Josiah , Walker Raymart , Acres Robert G. , Bakker Eric , De Marco Roland , Crespo Gaston A.
Published: July 2016

We report on the first direct spectroscopic evidence of the capacitive ion-to-electron transducing mechanism of carbon nanomaterials in solid contact polymeric ion-selective electrodes (SC-ISEs).
An enhanced extended hook method to realize tetranuclear metal clusters embedded in energetic metal–organic framework channels
Authors: Xiao Yu , Wang Shuai-Hua , Xu Jian-Gang , Sun Cai , Li Rong , Zhao Ya-Ping , Yan Yong , Zheng Fa-Kun , Guo Guo-Cong
Published: July 2016

Rare tetranuclear Zn clusters were successfully embedded into energetic 3D metal–organic framework channels by an extended bifunctional tetrazolate–carboxylate hook ligand.
On the fractality of the Freundlich adsorption isotherm in equilibrium and non-equilibrium cases
Authors: Borys Przemysław , Grzywna Zbigniew J.
Published: July 2016

This work relates the fractal properties of the adsorbent to the exponent of the Freundlich Isotherm of adsorption.
Topography evolution of 500 keV Ar4+ ion beam irradiated InP(100) surfaces – formation of self-organized In-rich nano-dots and scaling laws
Authors: Sulania Indra , Agarwal Dinesh C. , Kumar Manish , Kumar Sunil , Kumar Pravin
Published: July 2016

We report the formation of self-organized nano-dots on the surface of InP(100) upon irradiating it with a 500 keV Ar4+ ion beam.
Element-selective resonant state in M-doped SnTe (M = Ga, In, and Tl)
Authors: Tan X. J. , Liu G. Q. , Xu J. T. , Shao H. Z. , Jiang J. , Jiang H. C.
Published: July 2016

SnTe is found to exhibit element-selective resonant state and its thermoelectric performance is predicted to be improved by In-X codoping.
Electrostatically enhanced F⋯F interactions through hydrogen bonding, halogen bonding and metal coordination: an ab initio study
Authors: Bauzá Antonio , Frontera Antonio
Published: July 2016

In this manuscript the ability of hydrogen and halogen bonding interactions, as well as metal coordination to enhance F⋯F interactions involving fluorine substituted aromatic moieties has been studied at the RI-MP2/def2-TZVPD level of theory.
Hydrogenation vs. H–D isotope scrambling during the conversion of ethylene with hydrogen/deuterium catalyzed by platinum under single-collision conditions
Authors: Dong Yujung , Ebrahimi Maryam , Tillekaratne Aashani , Simonovis Juan Pablo , Zaera Francisco
Published: July 2016

The catalytic hydrogenation of ethylene promoted by platinum was studied under a unique regime representing pressures in the mTorr range and single-collision conditions.
Influence of Fe substitution on the Jahn–Teller distortion and orbital anisotropy in orthorhombic Y(Mn1−xFex)O3 epitaxial films
Authors: Haw Shu-Chih , Lee Jenn-Min , Chen Shin-Ann , Lu Kueih-Tzu , Lee Ming-Tao , Pi Tun-Wen , Lee Chih-Hao , Hu Zhiwei , Chen Jin-Ming
Published: July 2016

The variation of the Jahn–Teller distortion and orbital anisotropy in orthorhombic YMnO3 single-crystal film upon Fe substitution was reported.
Fabrication of a nano-drug delivery system based on layered rare-earth hydroxides integrating drug-loading and fluorescence properties
Authors: Gu Qingyang , Chen Wen , Duan Fei , Ju Ruijun
Published: July 2016

Intercalation of naproxen (NPX) into LEuH to form nanocomposites with low cytotoxic effects, which can control the release of NPX.
Interrogating heterobimetallic co-catalytic responses for the electrocatalytic reduction of CO2 using supramolecular assembly
Authors: Machan Charles W. , Kubiak Clifford P.
Published: July 2016

The use of hydrogen-bonding interactions to direct the non-covalent assembly of a heterobimetallic supramolecular system with Re and Mn bipyridine-based electrocatalysts is reported.
A novel functional full-fat hard cheese containing liposomal nanoencapsulated green tea catechins: manufacture and recovery following simulated digestion
Authors: Rashidinejad Ali , Birch E. John , Everett David W.
Published: July 2016

We incorporated nanoliposomal encapsulated green tea catechins into a full-fat hard cheese that was ripened at 8 °C for 90 days and underwent simulated gastrointestinal digestion.
Stability and bioaccessibility of anthocyanins in bakery products enriched with anthocyanins
Authors: Karakaya Sibel , Simsek Sebnem , Eker Alper Tolga , Pineda-Vadillo Carlos , Dupont Didier , Perez Beatriz , Viadel Blanca , Sanz-Buenhombre Marisa , Rodriguez Alberto Guadarrama , Kertész Zsófia , Hegyi Adrienn , Bordoni Alessandra , El Sedef Nehir
Published: July 2016

Anthocyanins, water soluble polyphenols, have been associated with several beneficial health effects.
In-gel activity-based protein profiling of a clickable covalent ERK1/2 inhibitor
Authors: Lebraud Honorine , Wright David J. , East Charlotte E. , Holding Finn P. , O'Reilly Marc , Heightman Tom D.
Published: July 2016

Thetrans-cyclooctenol/tetrazine click reaction was used for in-gel ABPP to determine the proteome-wide selectivity profile of a covalent ERK1/2 inhibitor.
Construction of metal–organic coordination networks with various metal-linker secondary building units: structures and properties
Authors: Huang Yong-Qing , Wan Yi , Chen Huai-Ying , Wang Yang , Zhao Yue , Xiao Xin-Feng
Published: July 2016

Three new metal–organic coordination networks with various metal-linker secondary building units are synthesized, which have luminescence and iodine adsorption properties.
Modern mass spectrometry for synthetic biology and structure-based discovery of natural products
Authors: Henke Matthew T. , Kelleher Neil L.
Published: July 2016

This highlight serves as a primer for those curious about the abilities of mass spectrometry for natural products discovery and engineering.
Observation of antisite domain boundaries in Cu2ZnSnS4 by atomic-resolution transmission electron microscopy
Authors: Kattan N. A. , Griffiths I. J. , Cherns D. , Fermín D. J.
Published: July 2016

Atomic resolution transmission electron microscopy has been used to examine antisite defects in Cu2ZnSnS4 (CZTS) kesterite crystals grown by a hot injection method.
Pyrimidine-based fluorescent COX-2 inhibitors: synthesis and biological evaluation
Authors: Tietz Ole , Kaur Jatinder , Bhardwaj Atul , Wuest Frank R.
Published: July 2016

Three novel and selective fluorescent pyrimidine-based COX-2 inhibitors have been synthesized and evaluated in COX-2 expressing human colon cancer cell line HCA-7.
Self-assembly of Ni-NTA-modified β-annulus peptides into artificial viral capsids and encapsulation of His-tagged proteins
Authors: Matsuura Kazunori , Nakamura Tomohiro , Watanabe Kenta , Noguchi Takanori , Minamihata Kosuke , Kamiya Noriho , Kimizuka Nobuo
Published: July 2016

His-tagged proteins were encapsulated into artificial viral capsids self-assembled from Ni-NTA-modified β-annulus peptides.
Synthesis of core/shell structured Pd3Au@Pt/C with enhanced electrocatalytic activity by regioselective atomic layer deposition combined with a wet chemical method
Authors: Liu Huiyuan , Song Yujiang , Li Shushuang , Li Jia , Liu Yuan , Jiang Ying-Bing , Guo Xinwen
Published: July 2016

Core/shell structured Pd3Au@Pt/C created by regioselective atomic layer deposition combined with a wet chemical method demonstrates improved electrocatalytic activity toward formic acid oxidation and oxygen reduction compared with commercial Pt/C.
Synergy between vanadium and molybdenum in bimetallic ZSM-5 supported catalysts for ethylene ammoxidation
Authors: Rhimi Baker , Mhamdi Mourad , Kalevaru Venkata Narayana , Martin Andreas
Published: July 2016

Ammoxidation of ethylene to acetonitrile was studied on V/ZSM-5, Mo/ZSM-5 and V–Mo/ZSM-5 catalysts prepared by a solid-state ion exchange method.
Fabrication and formation mechanism of Ce2O3–CeO2–CuO–MnO2/CNTs catalysts and application in low-temperature NO reduction with NH3
Authors: Zhang Yanbing , Zheng Yuying , Chen Xuehong , Fu Binbin
Published: July 2016

Ce2O3–CeO2–CuO–MnO2/CNTs catalysts were synthesized via a redox strategy, and presented 58–85% NO conversion at 80–180 °C.
Sulfonated nanocrystal cellulose/sulfophenylated poly(ether ether ketone ketone) composites for proton exchange membranes
Authors: Wei Yingcong , Li Xiaobai , Hu Qiuxue , Ni Chuangjiang , Liu Baijun , Zhang Mingyao , Zhang Huixuan , Hu Wei
Published: July 2016

The suggested proton transport path in the composite membranes.
Multifunctional Fe2O3/CeO2 nanocomposites for free radical scavenging ultraviolet protection
Authors: Cardillo Dean , Weiss Martin , Tehei Moeava , Devers Thierry , Rosenfeld Anatoly , Konstantinov Konstantin
Published: July 2016

In this study we synthesized Fe2O3/CeO2 composite nanoparticles with high ultraviolet absorption and free radical scavenging properties for application as multifunctional ultraviolet (UV) filters.
Effect of core–shell nanoparticle geometry on the enhancement of the proton relaxivity value in a nuclear magnetic resonance experiment
Authors: Venkatesha N. , Qurishi Yasrib , Atreya Hanudatta S. , Srivastava Chandan
Published: July 2016

This work illustrates the effect of core–shell nanoparticle geometry on the enhancement of the proton relaxivity value in a nuclear magnetic resonance experiment.
Graphitic C3N4as a powerful catalyst for all-vanadium redox flow batteries
Authors: Huang Yuqing , Huo Jia , Dou Shuo , Hu Kui , Wang Shuangyin
Published: July 2016

A novel carbon felt electrode modified with carbon nitride (C3N4) has been developed to improve the electrochemical performance with a VO2+/VO2+redox pair.
Triple-targeting Gram-negative selective antimicrobial peptides capable of disrupting the cell membrane and lipid A biosynthesis
Authors: Postma T. M. , Liskamp R. M. J.
Published: July 2016

A potent Gram-negative selective triple-targeting antimicrobial peptide was developed that attacks the membrane and inhibits two enzymes involved in early lipid A biosynthesis.
Spin phase protection in interference of electron spin waves in lightly hydrogenated graphene
Authors: Kato T. , Kamijo J. , Nakamura T. , Ohata C. , Katsumoto S. , Haruyama J.
Published: July 2016

Here, we have realized the extremely light hydrogenation of a graphene surface on SiO2 by precisely controlling the amount of electron beam (EB) irradiation to a specific EB resist including hydrogen atoms, treated on graphene.
Iron nitrate/TEMPO-catalyzed aerobic oxidative synthesis of quinazolinones from alcohols and 2-aminobenzamides with air as the oxidant
Authors: Hu Yongke , Chen Lei , Li Bindong
Published: July 2016

A highly efficient, one-pot Fe(NO3)3/TEMPO-catalyzed protocol for aerobic oxidative synthesis of quinazolinones from easily accessible primary alcohols and 2-aminobenzamides with molecular oxygen as the terminal oxidant.
PEGylated graphene oxide-based nanocomposite-grafted chitosan/polyvinyl alcohol nanofiber as an advanced antibacterial wound dressing
Authors: Dubey Poornima , Gopinath P.
Published: July 2016

Designing composite nanomaterials that display multiple antibacterial mechanisms offers new prototypes against bacterial resistance.
Methylene blue incorporated mesoporous silica microsphere based sensing scaffold for the selective voltammetric determination of riboflavin
Authors: Gupta Rupali , Rastogi Pankaj Kumar , Srivastava Utkarsha , Ganesan Vellaichamy , Sonkar Piyush Kumar , Yadav Dharmendra Kumar
Published: July 2016

Methylene blue incorporated sulfonic acid functionalized mesoporous silica microspheres is synthesized and utilized as effective sensing scaffold for electrochemical determination of nanomolar levels of riboflavin.
An ultrafine V2O3 modified hierarchical porous carbon microsphere as a high performance cathode matrix for lithium–sulfur batteries
Authors: Tang Ruwen , Li Xueliang , Ding Zhongqiang , Zhang Luyao
Published: July 2016

An ultrafine V2O3 modified carbon microsphere (VCM) was effectively prepared by a facile wet impregnation method and used as a cathode matrix for lithium–sulfur batteries.
Accurate quantification of inter-domain partition coefficients in GUVs exhibiting lipid phase coexistence
Authors: Sarmento M. J. , Pinto S. N. , Coutinho A. , Prieto M. , Fernandes F.
Published: July 2016

Giant unilamellar vesicles (GUVs) with phase coexistence allow for the recovery of inter-domain partition coefficients (Kp) of fluorescent molecules through comparison of fluorescence intensities in each phase.
Simply controllable growth of single crystal plasmonic Au–Ag nano-spines with anisotropic multiple sites for highly sensitive and uniform surface-enhanced Raman scattering sensing
Authors: Chen Dongzhen , Song Zhongxiao , Chen Feng , Huang Jian , Wei Jing , Zhao Yongxi
Published: July 2016

Simply synthesizing Au core@Au–Ag alloy spine nanostructures with a highly tunable LSPR band and dense “hot spots” for SERS sensing.
Highly thermally conductive UHMWPE/graphite composites with segregated structures
Authors: Feng C. P. , Chen L. , Wei F. , Ni H. Y. , Chen J. , Yang W.
Published: July 2016

Polymer composites with segregated structures based on ultrahigh molecular weight polyethylene (UHMWPE) and graphite flakes were fabricated by a novel binder-mixing method and high thermal conductivity of the composites was achieved.
Lithiation-driven structural transition of VO2F into disordered rock-salt LixVO2F
Authors: Chen Ruiyong , Maawad Emad , Knapp Michael , Ren Shuhua , Beran Přemysl , Witter Raiker , Hempelmann Rolf
Published: July 2016

Disordered rock-salt LixVO2F formed through electrochemical lithiation exhibits promising performance when evaluated as a cathode material for Li batteries.
Enhanced photovoltaic performances of novel all-ionic liquid integrated poly(acrylic acid/polyethylene glycol) gel electrolytes in quasi-solid-state dye-sensitized solar cells
Authors: Sun Weifu , Xu Haitao
Published: July 2016

Quasi-solid-state DSSCs from ionic liquid imbibed poly(AA/PEG) gel electrolyte with interconnected 3D porous structure have demonstrated enhanced ionic conductivity, thermal stability and photovoltaic performances.
Structural, physical and chemical properties of nanostructured nickel-substituted ceria oxides under reducing and oxidizing conditions
Authors: Fuentes R. O. , Acuña L. M. , Albornoz C. A. , Leyva A. G. , Sousa N. , Figueiredo F. M.
Published: July 2016

Nanocrystalline Ni-substituted ceria is highly reversible and it has an extraordinary redox cyclicality associated to a high thermochemical stability of the material at relatively high temperature.
Facile fabrication of well-defined polyaniline microtubes derived from natural kapok fibers for supercapacitors with long-term cycling stability
Authors: Xu Weibing , Mu Bin , Zhang Wenbo , Wang Aiqin
Published: July 2016

Well-defined polyaniline microtubes derived from natural kapok fibers exhibit long-term cycling stability as electrode materials of supercapacitors.
Total chemical synthesis of proteins without HPLC purification
Authors: Loibl S. F. , Harpaz Z. , Zitterbart R. , Seitz O.
Published: July 2016

This work presents the first method for the rapid chemical total on-resin synthesis of proteins that proceeds without a single HPLC-purification step.
Scandium-catalysed intermolecular hydroaminoalkylation of olefins with aliphatic tertiary amines
Authors: Nako Adi E. , Oyamada Juzo , Nishiura Masayoshi , Hou Zhaomin
Published: July 2016

A homoleptic scandium trialkyl complex in combination with a borate compound served as an excellent catalyst for the C–H addition of aliphatic tertiary amines to various olefins.
Controllable synthesis of N-doped hollow-structured mesoporous carbon spheres by an amine-induced Stöber-silica/carbon assembly process
Authors: Liu Chao , Wang Jing , Li Jiansheng , Hu Xingru , Lin Peng , Shen Jinyou , Sun Xiuyun , Han Weiqing , Wang Lianjun
Published: July 2016

An amine-induced Stöber-silica/carbon assembly process is developed for the controllable synthesis of N-doped carbon spheres.
A 3D hierarchical assembly of optimized heterogeneous carbon nanosheets for highly efficient electrocatalysis
Authors: Wan Gang , Ma Ming , Jia Alec (Yi) , Chen Lisong , Chen Yu , Cui Xiangzhi , Chen Hangrong , Shi Jianlin
Published: July 2016

A 3D assembly of crumpled nitrogen-doped carbon nanosheets with reactant-accessible hierarchical frameworks and well-integrated iron carbide nanoparticles encased on the plane of subunits was constructed and demonstrated as an excellent ORR catalyst.
Highly durable Pt nanoparticle-supported carbon catalysts for the oxygen reduction reaction tailored by using an ionic liquid thin layer
Authors: Yoshii Kazuki , Yamaji Keisuke , Tsuda Tetsuya , Matsumoto Hiroaki , Sato Takeshi , Izumi Reiko , Torimoto Tsukasa , Kuwabata Susumu
Published: July 2016

Pt nanoparticle (NP)-supported SWCNTs and Vulcan® XC-72 produced using a Pt NP-dispersed IL prepared by sputtering show an unexpected high durability as electrode catalysts for the oxygen reduction reaction due to the existence of an IL thin layer.
The first aggregation-induced emission fluorophore as a solution processed host material in hybrid white organic light-emitting diodes
Authors: Lee Yi-Ting , Chang Yung-Ting , Chen Chao-Tsen , Chen Chin-Ti
Published: July 2016

TheCzPATPEAIE fluorophore for a solution processed host material in hybrid white OLEDs.
Thermal layer-by-layer preparation of oriented films of a Cu(i) ionic inorganic–organic hybrid material showing semiconducting and SHG properties
Authors: Marinotto D. , Danelli S. G. , Giaretta A. , Lucenti E. , Stadler P. , Tordin E. , Mattei G. , Scavia G. , Ugo R. , Cariati E.
Published: July 2016

The non-linear optical behavior emerges along the surface plane by sequential deposition and annealing of CuI and organic iodide.
New graduate transition to practice: how can the literature inform support strategies?
Authors: Moores Alis , Fitzgerald Cate
Published: July 2016

Objective
The transition to practice for new graduate health professionals has been identified as challenging, with health services typically adopting a range of support and management strategies to assist safe professional practice. Queensland’s state-wide Occupational Therapy Clinical Education Program supporting new graduates within public sector health facilities conducted a narrative literature review to identify evidence-based recommended actions that would assist new graduate occupational therapists’ to transition from student to practitioner.

Method
Searches of Medline, CINAHL and PubMed databases were used to locate articles describing or evaluating occupational therapy new graduate support actions.

Results
The themes of supervision, support and education emerged from the literature. Additionally, four interactions were identified as factors potentially influencing and being influenced by the processes and outcomes of supervision, support and education actions. The interactions identified were professional reasoning, professional identity, an active approach to learning and reflective practice.

Conclusions
The interactions emerging from the literature will serve to inform the delivery and focus of supervision, support and education for new graduate occupational therapists as they transition to practice. The results may have application for other health professions.

What is known about the topic?
The transition to practice for new graduate occupational therapists has been reported as challenging with health services implementing various actions to support and assist this transition. A previous literature review of recommended support strategies could not be found providing an impetus for this enquiry.

What does this paper add?
This narrative literature review identified three themes of actions supporting the transition of new graduates from student to practitioner. In addition to these themes of supervision, support and education, also emerging from the literature were factors identified as important to facilitating the transition of new graduates to the workplace. These factors, or interactions, are identified in this paper as professional reasoning, professional identity, an active approach to learning, and reflective practice. It is proposed that these interactions have an effect on and can be effected by supervision, support and education actions. The articulation between the interactions and the themes was a notable outcome emerging from this literature review.

What are the implications for practitioners?
This literature review will assist those planning actions to guide new graduates’ transition into practice. It is proposed that the methods of implementing supervision, support and education actions are optimised by the identified interactions.