bluuebunny/crossref_metadata_2025 huggingface dataset:
Policía y dominio eminente como técnicas de intervención en el Estado preconstitucional
Authors: Fernández-Valmayor José Luis Carro
Published: June 2019

Este artigo trata do poder de polícia e do domínio eminente como técnicas de intervenção no Estado pré-constitucional. Inicialmente, distingue-se o direito privado do direito administrativo diante de uma perspectiva histórica. Discorre-se acerca da concentração de poder no absolutismo, nas mãos do príncipe, do poder de polícia e do nascimento do Estado moderno. Aborda-se sobre o Estado absoluto e a sua técnica de intervenção na esfera jurídicaprivada. Menciona-se acerca da doutrina do tesouro e as suas concepçõesno direito romano e na doutrina moderna. Citam-se interpretações de váriosdoutrinadores acerca da doutrina do tesouro. Por fim, apontam-se motivosda imprecisão da doutrina do tesouro segundo a doutrina moderna.
A função econômico-social da propriedade: estudos de casos no âmbito dos impactos econômicos das decisões judiciais
Authors: Leal Rogério Gesta
Published: June 2019

A história da propriedade no Ocidente é marcada fortemente por suamatiz privada, centrada nos direitos individuais, razão pela qual a exigência de que se agreguem a ela funções sociais é algo que implica a revisão de alguns paradigmas culturais, notadamente no âmbito da discussão jurisdicional.
A globalização, o aceleramento do processo de exclusão e o caso do sistema da ações afirmativas no ensino superior
Authors: Neves Osias Paese , Both Laura Garbini
Published: June 2019

O artigo trata da questão dos direitos fundamentais consagrados naConstituição Federal de 1988 frente aos paradoxos advindos do processo deglobalização e aceleração da exclusão social, em especial para a população negra. Tratar-se-á da emergência da identificação de direito com estado e da crítica do modelo moderno promovida por Boaventura de Sousa Santos. A noção de emancipação social e as desigualdades sociais que afligem a população negra serão tomadas a partir de numa leitura que conjuga elementos do direito com a antropologia e a história. Problematizar-se-á o debate em torno das ações afirmativas e a questão da identidade cultural da população negra na difícil relação de discriminação positiva e identidade cultural.
O princípio constitucional da moralidade e a participação popular na Administração Pública
Authors: Langoski Deisemara Turatti
Published: June 2019

A moralidade administrativa situa-se como um instituto jurídicoinovador, se levado em consideração que somente com a Constituição Federal de 1988 tornou-se de observância obrigatória para a Administração Pública. Os indivíduos passaram a cuidar do fator moral, diante das imoralidades existentes no cenário público, o que gerou a necessidade de participação efetiva dos cidadãos nas ações preconizadas e executadas pelo Estado. As ações da Administração Pública deverão estar de acordo com os princípios e valores que o indivíduo ou a sociedade em certo tempo e espaço possui. Quando os indivíduos se agrupam para melhorar suas vidas, surge a necessidade de suprir seus anseios, alcançar metas, progredir. A moralidade como princípio constitucional da Administração Pública deve estar na execução da função administrativa e na vontade precípua do Estado: o interesse público. O efetivo exercício da cidadania pelos indivíduos é primordial para que se verifique o respeito e acatamento da moralidade no âmbito da Administração, e isto se perfaz através dos variados instrumentos dispostos no ordenamento jurídico de participação popular na gestão pública. Exercer a cidadania garante aoindivíduo a efetiva participação nos negócios do Estado e é meio eficaz decontrole das ações dos agentes públicos frente ao interesse da coletividade.
Mutational profile by targeted next generation sequencing of non-small cell lung cancer in the Mexican population
Authors: Hernández-Pedro Norma , Soca-Chafre Giovanny , Alaez-Versón Carmen , Carrillo-Sánchez Karol , Avilés-Salas Alejandro , Vergara Edgar , Arrieta Oscar
Published: June 2019

Objective. Targeted next-generation sequencing (t-NGS) has revolutionized clinical diagnosis allowing multiplexed de­tection of genomic alterations. This study evaluated the profile of somatic mutations by t-NGS in Mexican patients with non-small cell lung cancer (NSCLC). Materials and methods. Genomic DNA was extracted from 90 lung adenocarcinomas and sequences were generated for a panel of 48 cancer ge­nes. Epidermal Growth Factor Receptor (EGFR) mutations were detected in parallel by quantitative PCR. Results. The mutational profile of NSCLC revealed alterations in 27 genes, where TP53 (47.8%) and EGFR (36.7%) exhibited the highest mutation rates. EGFR Q787 mutations were present in 14 cases (15.6%), 10 cases had exon 19 deletions (11.1%), seven cases had L858R (7.8%). The mutational frequency for genes like EGFR, MET, HNF1A, HER2 and GUSB was different compared to caucasian population. Conclusion. t-NGS improved NSCLC treatments efficacy due to its sensitivity and specificity. A distinct pattern of somatic mutations was found in Mexican population.
Ombitasvir/Paritaprevir/Ritonavir & Dasabuvir ± Ribavirin following protease inhibitors failure - A Prospective Multi-Centre Trial
Authors: Deutsch Liat , Houri Inbal , Ben-Ari Ziv , Shlomai Amir , Veitsman Ella , Cohen-Ezra Oranit , Issachar Assaf , Mor Orna , Gozlan Yael , Bruck Rafael , Menachem Yoram , Zelber-Sagi Shira , Katchman Helena , Shibolet Oren
Published: June 2019

Background: Hepatitis C virus (HCV) infection is a leading cause of chronic liver disease and hepatocellular carcinoma. Treatment with first generation protease inhibitors (PI)+peg-interferon (pegIFN) and ribavirin (RBV) achieved sustained virologic response (SVR) rates of 65-75% but was associated with multiple side effects. The aim of this study was to evaluate safety and efficacy of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir (3D)±RBV in HCV genotype 1 patients that failed previous treatment with first generation PIs.
Methods: An investigator-initiated, open-label, multi-centre clinical trial. HCV Genotype 1 patients who were previously null/partial responders or relapsers to telaprevir, boceprevir or simepravir+pegIFN/RBV and met eligibility criteria were included. 3D±RBV were administrated for 12 or 24 weeks according to label. The primary outcome was antiviral response (SVR12); Secondary outcomes were patient reported outcomes, adverse events and resistance associated variants.
Results: Thirty-nine patients initiated treatment according to study protocol (59% men, age 54.0±8.7 years, BMI 28.7±4.5 kg/m2). Thirty-seven (94.9%) completed the study. Thirty-five patients had genotype 1b (9 cirrhotics) and 4 had genotype 1a (2 cirrhotics). Intention-to-treat SVR12 was 92.3% and per-protocol SVR12 was 97.3%. The rate of advanced fibrosis (FibroScan® score F3-4) declined from 46.2% to 25.7% (P=0.045). Abnormal ALT levels declined from 84.6% to 8.6% (P<0.001). Seven patients (17.9%) experienced serious adverse events (3 Psychiatric admissions, 1 pneumonia, 1 ankle fracture, 2 palpitations), and 12 patients (30.8%) experienced self-reported adverse events, mostly weakness.
Conclusion: 3D±RBV is safe and effective in achieving SVR among patients with HCV genotype 1 who failed previous first-generation PI treatment.
Clinical trial number: NCT02646111
Childbirth Experience Questionnaire (CEQ): Research Proposal for Translation and Validation into Sinhala Language
Authors: Patabendige Malitha
Published: June 2019

Introduction

The Childbirth Experience Questionnaire (CEQ) is a Sweden origin, self-administered questionnaire to assess satisfaction of women in different aspects of their first labour and birth. It measures four main domains of the woman’s childbirth experience. Those are own capacity, professional support, perceived safety and participation, comprising of 22 items.

Objective

To conduct a linguistic translation, to conduct a validation study and to assess the psychometric properties of the Sinhala version of the CEQ.
Protein kinase C isozymes; predictors of progression free survival in NSCLC patients
Authors: Halvorsen Ann Rita , Haugen Mads Haugland , Öjlert Åsa Kristina , Lund-Iversen Marius , Jørgensen Lars , Solberg Steinar , Mælandsmo Gunhild M. , Brustugun Odd Terje , Helland Åslaug
Published: June 2019

Background

Protein expression is deregulated in cancer, and the proteomic changes observed in lung cancer may be a consequence of mutations in essential genes. The purpose of this study was to identify protein expression associated with prognosis in lung cancers stratified by smoking status, molecular subtypes, and EGFR-, TP53- and KRAS-mutations.

Methods

We performed profiling of 295 cancer-relevant phosphorylated and non-phosphorylated proteins, using reverse phase protein arrays. Biopsies from 80 patients with operable lung adenocarcinomas were analyzed for protein expression and association with progression free survival (PFS) were studied.

Results

Spearman rank correlation analysis identified 56 proteins with significant association to PFS (p<0.05). High expression of protein kinase C (PKC)-α and the phosporylated state of PKC-α, PKC-β and PKC-δ, showed the strongest positive correlation to PFS, especially in the wild type samples. This was confirmed in gene expression data from 186 samples. Based on protein expression, unsupervised hierarchical clustering separated the samples into four subclusters enriched with the molecular subtypes TRU, PI or PP (p=0.0001). Subcluster 2 contained a smaller cluster (2a) enriched with samples of the subtype PP, low expression of the PKC isozymes, and associated with poor PFS (p=0.003) compared to the other samples. Subcluster 2a revealed increased expression of neuroendocrine markers, supporting the aggressive behavior. Low expression of the PKC isozymes in the subtype PP and a reduced relapse free survival was confirmed with the TCGA LUAD samples.

Conclusion

This study identified different proteins associated with PFS depending on molecular subtype, smoking- and mutational-status, with PKC-α, PKC-β and PKC-δ showing the strongest correlation. Cluster analysis detected a subgroup of samples enriched for samples of the PP subtype and poor PFS, which may benefit from a more aggressive treatment regimen.
Harvest Maturity and Storage Temperature Affect Postharvest Quality of ‘Wanda’ Datil Hot Pepper Grown under Protected Culture
Authors: Lon Kan Elena E. , Sargent Steven A. , Cantliffe Daniel J. , Berry Adrian D. , Shaw Nicole L.
Published: June 2019

Datil hot pepper (Capsicum chinense) has potential for increased production due to its unique, spicy flavor and aroma. However, few reports have been published related to postharvest handling characteristics. The purpose of this study was to determine the effect of harvest maturity on fruit quality under simulated commercial storage conditions. ‘Wanda’ datil pepper plants were grown hydroponically under protected culture. Fruit were harvested at yellow and orange maturity stages, placed in vented clamshell containers, and stored at 2, 7, or 10 °C for 21 days. Peppers harvested at yellow stage maintained greater quality than orange peppers during storage at all temperatures. Marketable fruit after 21 days for peppers harvested at the yellow stage was 94% (2 °C), 88% (7 °C), and 91% (10 °C); that for orange-stage peppers was 68%, 74%, and 82% for the same respective temperatures. No chilling injury (CI) symptoms were observed in these tests. Initial pepper moisture content was 90%, decreasing only slightly during 21 days of storage; weight loss ranged from 2% to 8%. Soluble solids content (SSC) was greater for peppers harvested at the orange stage (9.5%) than for those at yellow stage (7.8%). Neither harvest maturity nor storage temperature affected total titratable acidity (TTA; 0.13%) or pH (5.3). Respiration rate varied with temperature but not by harvest maturity and ranged from 12 to 25 mg·kg−1 per hour after 8 days of storage. Peppers harvested orange contained double the amount of total carotenoids as yellow fruit. Carotenoid content for yellow and orange peppers was 58 and 122 µg·g−1, respectively. Capsaicinoid content ranged from 1810 to 4440 µg·g−1 and was slightly greater for orange-harvested peppers. Datil peppers harvested at the yellow stage and stored in vented clamshell containers had better quality than peppers harvested at the orange stage after 21 days at 2 °C.
THE IMPACT OF KNOWLEDGE MANAGEMENT ON SUSTAINABLE ACTIVITIES OF HIGHER EDUCATION INSTITUTION
Authors: Grybauskienė Ieva , Jankauskienė Žymantė , Kubilienė Erika
Published: June 2019

The main responsibilities for the European Higher Education Area are based on processes‘ execution through the knowledge, therefore each institution has to evaluate its own knowledge and organize activities implementing these knowledge goals. Knowledge management (KM) is considered one of the main disciplines of the 21st century, which helps organizations to create a competitive advantage, to identify unique knowledge within the organization and to develop further knowledge creation and integration into activities. KM can be analyzed specifically, however it‘s recognized that human resources remain the most important factor, which leads to effective implementation of the stages of KM. Preparing trained staff for the knowledge society and economy, who are able to assess the benefits and importance of knowledge, higher education institutions (HEI) shape the future behavior of future market players, define the need for future competences and values. Following this example, it‘s useful to analyze, how KM processes are integrated into the academic community and which role the KM plays in the development of HEI‘s activity and competence.
ENTROPY-INFORMATIONAL APPROACH TO ANALYSIS OF SELF-OGRANIZATION OF BANKING SYSTEM
Authors: Tkachuk Natalia
Published: June 2019

The evolving economy today is non-stationary in the nature of its character of behavior which becomes the reason of emergence of imbalances and instability of the market environment that cause the emergence of nonlinear processes in functioning of the banking system which may carry a threat to its development. Super fast tempos of change in the globalized world generate flows of institutional and innovative disturbances that test banks and banking systems for viability and encourage them to study the peculiarities of their behavior in terms of non-linearity and non-equilibrium. Knowledge and interpretation of synergetic properties of the banking system today have not only theoretical but also practical significance for development and implementation of the concept of self-organization of banks.
The theoretical questions of mutual influence and interconnection of entropy and information on the processes of self-organization in the banking system are considered. The functioning of the banking system in an unstable environment with chaotic and orderly behavioral stages is characterized by a nonlinear dynamics of entropy, as well as a significant dependence on the influence of management information that enters the system. Saturation of the banking system with this information makes it possible to force out chaos from it, it increases its orderliness and effect of functioning.
From the point of view of entropy and informational approach, the nature and conditions of self-organization in the banking system are disclosed. It was established, that fundamental condition for self-organization in the banking system is to transfer the system to a non-equilibrium state when it becomes quite sensitive to external disturbances. It is noted, that entropy represents a measure of disorder of the system, and its growth increases chaos and can lead to devastating consequences in the functioning of the system. The processes of self-organization in the banking system will only be possible if its order is growing.
DEVELOPMENT OF PREVENTING MEANS FOR RABBITS’ COCCIDIOSIS
Authors: Shkromada Oksana , Skliar Oleksandr , Paliy Andriy , Ulko Larysa , Suprun Yulia , Naumenko Oleksandr , Ishchenko Katerina , Kysterna Olesia , Musiienko Oleksii , Paliy Anatoliy
Published: June 2019

The great problem of rabbits breeding today is coccidiosis. An agent of the disease spreads not only through ill animals and is preserved well in the external environment. Oocysts of coccidia live in cells for a long time, so even temporal vacation of an accommodation between placing of rabbits doesn’t prevent infection. It was experimentally proved, that there is a very limited spectrum of means that are coccidiostatics. For preventing and controlling rabbits’ eimeriosis, coccidiostatic means were tested. It is very difficult to annihilate coccidia in vivo and in vitro because of peculiarities of their construction. The aim of the first experiment was to determine the influence of an acidifier Cronocyde L and its components on oocysts of coccidia that allows to determine an optimal composition and concentration of the preparation. At conducting the research, there was used the flotation method of Fulleborn and McMaster one for calculating oocysts. The aim of the second experiment was to determine the influence of the acidifier Cronocyde L standard and Cronocyde L concentrate (1 ml/1l of water) on the intensity of the living mass increment in rabbits. For that there were used clinical, hematological, zootechnical and microscopic methods. Optimal results in the experiment were obtained at using Cronocyde L concentrate and Cronocyde L standard in concentration 0,1 %: maximal growth and health status of rabbits, biochemical indices of blood serum were within the physiological norm. It testifies to the effectiveness of this preparation at eimeriosis of rabbits and to harmlessness for them. The studies, realized under laboratory conditions, prove the effectiveness of the offered means.
FREQUENCY ANALYSIS OF MEDICINAL PRESCRIPTS AT PHARMACOTHERAPY OF BRONCHIAL ASTHMA IN CHILDREN
Authors: Kostiuk Iryna , Dziuba Olha , Makukha Mikola , Golopikho Larisa
Published: June 2019

Today, bronchial asthma is the most widespread childhood chronic respiratory disease in the world. To make managerial decisions in the health care system of Ukraine and to identify priority areas for the response to this disease, it is necessary to carry out a quantitative analysis of the appointment letters and the proportion of patients who received specific drugs for determining the main areas of therapy.

Aim. Carrying out of frequency analysis of medical prescriptions at pharmacotherapy of bronchial asthma in children.

Materials and methods. 574 medical cards of an indoor patient with the main diagnosis of "Bronchial asthma", received at the Kyiv City Children's Clinical Hospital №2. A retrospective frequency analysis of the prescribing of drugs for archival data of appointment letters was conducted.

Results. The conducted analysis of patients by age and sex allowed to establish the correspondence of the obtained results with the results of previous scientific studies on gender differences in the prevalence of bronchial asthma in children. In 45.3 % of the children, the length of stay was 2-10 days, and in 37.3 % – 11–20 days, indicating a sufficiently long period of inpatient treatment. According to the letters of appointment in the medical records of the inpatient patient, the physicians carried out 1983 appointments, of which 1867 were medicated (94.2 %), and 116 were non-medicated methods (5.8 %). The medical appointments of doctors included 1763 medicines. Of these, 94.4 % are medicines belonging to 11 groups according to ATC classification, 1.5 % – solutions for washing, irrigation, treatment, 0.3 % - dietary supplements, 0.1 % – homeopathic preparations, 3.7 % – other. The data that was obtained when calculating the intensity of the target varies in the range of 0.0006 to 0.07. The highest rates had only 2 drugs – Ventolin nebuli and Pulmicort, which were available in 22.3 % and 23.0 % of the patient's medical cards respectively, that is, every fifth patient. It was found that the ratio of drugs of domestic and foreign manufacture is 34.2 % (20 pharmaceutical companies) and 65.8 % (25 producing countries), respectively.

Conclusions. The received data of the conducted analysis of prescriptions of medicinal products allow establishing a significant nomenclature of medical appointments for children with bronchial asthma. The promising direction for domestic pharmaceutical companies in the production of drugs for the treatment of the examined nosology was revealed. At the same time, the frequency analysis of the nomenclature of drugs can be used in the selection of drugs for reimbursement programs and medical insurance after further pharmacoeconomic studies.
Strategies for Development of High-Performance Graphene-Based Supercapacitor
Authors: de Oliveira Mário César Albuquerque , de Oliveira Helinando Pequeno
Published: June 2019

The development of high-performance supercapacitors requires efforts in materials design
and nanotechnology to provide more efficient electrodes with higher electrochemical window, capacitance,
energy and power density. In terms of candidates for electrodes, the high surface area of graphene
(2630 m2g-1) makes this carbon derivative a widely explored building block for supercapacitor
electrodes. Herein, it is presented a review about the state-of-art in surface modification of graphene
derivatives with the aim of avoiding restacking processes in nanosheets. It allows that Faradaic and
non-Faradaic mechanisms can be synergically explored to reach not only superior results in power
density but in energy density, a typical drawback in supercapacitors (by comparison with conventional
batteries), introducing graphene-based supercapacitors as promising candidates for energy
storage devices.
Deep Learning Intervention for Health Care Challenges: Some Biomedical Domain Considerations
Authors: Tobore Igbe , Li Jingzhen , Yuhang Liu , Al-Handarish Yousef , Kandwal Abhishek , Nie Zedong , Wang Lei
Published: June 2019

The use of deep learning (DL) for the analysis and diagnosis of biomedical and health care problems has received unprecedented attention in the last decade. The technique has recorded a number of achievements for unearthing meaningful features and accomplishing tasks that were hitherto difficult to solve by other methods and human experts. Currently, biological and medical devices, treatment, and applications are capable of generating large volumes of data in the form of images, sounds, text, graphs, and signals creating the concept of big data. The innovation of DL is a developing trend in the wake of big data for data representation and analysis. DL is a type of machine learning algorithm that has deeper (or more) hidden layers of similar function cascaded into the network and has the capability to make meaning from medical big data. Current transformation drivers to achieve personalized health care delivery will be possible with the use of mobile health (mHealth). DL can provide the analysis for the deluge of data generated from mHealth apps. This paper reviews the fundamentals of DL methods and presents a general view of the trends in DL by capturing literature from PubMed and the Institute of Electrical and Electronics Engineers database publications that implement different variants of DL. We highlight the implementation of DL in health care, which we categorize into biological system, electronic health record, medical image, and physiological signals. In addition, we discuss some inherent challenges of DL affecting biomedical and health domain, as well as prospective research directions that focus on improving health management by promoting the application of physiological signals and modern internet technology.
Monitoring Immobilized Elderly Patients Using a Public Provider Online System for Pressure Ulcer Information and Registration (SIRUPP): Protocol for a Health Care Impact Study
Authors: Vera-Salmerón Eugenio , Rutherford Claudia , Dominguez-Nogueira Carmen , Tudela-Vázquez María Pilar , Costela-Ruiz Victor J , Gómez-Pozo Basilio
Published: June 2019

Background

Pressure ulcers represent a major challenge to patient safety in the health care context, presenting high incidence (from 7% to 14% in Spain) and increased financial costs (€400-600 million/year) in medical treatment. Moreover, they are a significant predictor of mortality. The prevention of pressure ulcers in long-term care centers and patients’ own homes is proposed as a priority indicator of health care quality. Early stage risk assessment and database recording are both crucial aspects of prevention, classification, diagnosis, and treatment.

Objective

This project proposes a 3-year study of immobilized patients residing in the Granada-Metropolitan Primary Healthcare District (DSGM) and monitored via the Pressure Ulcer Information and Registration System (SIRUPP, Spanish initials). The project aims to estimate the incidence of PUs among immobilized elderly patients, analyze the health-related quality of life of these patients by using the Pressure Ulcer Quality of Life (PU-QoL) instrument in a sample of 250 patients, determine the average time to complete wound healing, estimate the rate of pressure ulcers–associated mortality, and assess the predictive value of the Braden and Mini Nutritional Assessment risk measurement scales in a sample of 1700 patients.

Methods

The DSGM runs SIRUPP, which is linked to patients’ electronic health records. Currently, 17,104 immobilized patients are monitored under this system. Health-related quality of life will be measured by patient self-reports using the Spanish Pressure Ulcer Quality of Life questionnaire, following cross-cultural adaptation and psychometric validation with respect to the English-language version.

Results

The project commenced in June 2017 and is expected to conclude in April 2020.

Conclusions

This study addresses two main health outcomes—the time needed for wound healing and the mortality associated with pressure ulcers—both of which might be accounted for by variations in clinical practice and the health-related quality of life of patients with pressure ulcers.

International Registered Report Identifier (IRRID)

DERR1-10.2196/13701
Spindle Cell Lipoma of the Scrotum
Authors: Iqbal Muhammad , Agarwal Sanjay , Shergill Iqbal S.
Published: June 2019

Spindle cell lipoma (SCL) in the scrotum is a very rare presentation with only a few cases reported in the literature. The most common sites for this benign lesion are the neck, shoulder, and back. We present a 72-year-old male patient with painless swelling on the left half of the scrotum with a histopathological diagnosis of SCL.
Diseño de una actividad didáctica para un curso de control automático basada en modelización matemática. Una propuesta desde la teoría antropológica de lo didáctico
Authors: Guzmán Patricia , Tomo Avenilde , Covián Olda
Published: June 2019

En esta comunicación, se presenta una propuesta metodológica del diseño de un REI, basada en el paradigma del cuestionamiento del mundo e inspirada en la metodología para el diseño de actividades didácticas basadas en modelización matemática Consuelo Macias (2012). El análisis de un curso de control automático resulta un elemento clave para determinar la cuestión generatriz que motiva el REI. El análisis a priori muestra la forma en que los estudiantes podrían desarrollar tres etapas del REI y utilizar las ecuaciones diferenciales para controlar la velocidad de un motor de corriente directa. La ruta metodológica para el diseño del REI, se considera útil para las formaciones profesionales.
What algebraic knowledge may not be learned with CAS-a praxeological analysis of Faroese exam exercises
Authors: Carlsen Louise M
Published: June 2019

We are interested in the potentials and pitfalls of introducing computer algebra systems in lower secondary school, investigating the case of the Faroese Islands. In order to identify what algebraic knowledge is tested in the final written exam in mathematics after the ninth grade, and how this would change if computer algebra systems were allowed at that exam, we analyse all exam exercises from the past 10 years in terms of the techniques required to solve the exercises both with and without symbolic tools. The comparison suggests that fundamental algebraic structures may not be learned if students consistently use computer algebra systems for the tasks given in the exam
Was Archaeopteryx able to fly? Authentic palaeontological practices in a museum programme
Authors: Achiam Marianne , Lindow Bent Erik Kramer
Published: June 2019

Authentic science education has received increased attention in recent years, but it remains unclear what constitutes authenticity. Here, we use notions from the Anthropological Theory of the Didactic to approach authenticity. We take a point of departure in an existing education programme in a museum, and analyse it to pinpoint what constitutes its authenticity. We then use the theory of didactical situations as a way to construct a reference model; this reference model constitutes an authenticity-optimised version of the programme. We conclude by briefly discussing the implications of our findings.
Factorisation des polynômes. Une étude basée sur le développement d’un PER
Authors: Guadagnini Míriam do Rocio , Dias Marlene Alves
Published: June 2019

The aim of this paper is to present partial results of an ongoing study, which investigates the teaching of polynomial factoring through analysis of didactic and mathematical praxeologies, institutional and personal relationships developed for their study, based on Brazilian official documents and textbooks for future intervention with a group of mathematics teachers and high school students. We take as theoretical foundation the anthropological theory of the didactic and as a methodology, study and research paths (SRP) by Chevallard and collaborators
Étude d’un processus de transposition didactique interne : cas de la réception par un professeur d’un PER monodisciplinaire et finalisé
Authors: Bernad Karine
Published: June 2019

La recherche en cours que nous présentons ici vise à être une contribution à l’étude de l’équipement praxéologique utile pour un professeur projetant de mettre en œuvre un parcours d’étude et de recherche qu’il s’est approprié à l’aide d’un document écrit et d’interactions avec une équipe de chercheurs et d’enseignants l’ayant conçu.
Le développement de la pensée algébrique dans le curriculum officiel en France et au Québec
Authors: Larguier Mirène
Published: June 2019

Dès l’école primaire l’entrée dans l’algèbre ne se réalise pas de la même façon selon le pays. Cette communication vise à mettre au jour pour les comparer les choix curriculaires officiels au niveau du primaire en France et au Québec en utilisant le cadre théorique de la TAD. D’un point de vue méthodologique, la communication vise également la construction d’outils spécifiques pour l’analyse d’un savoir à enseigner dans le cadre de la TAD
El uso del esquema herbartiano para analizar un REI online para la formación del profesorado de secundaria
Authors: Farras Berta Barquero , Casabó Marianna Bosch , Romo-Vázquez Avenilde
Published: June 2019

Presentamos los principales elementos de un REI para la formación del profesorado (REI-FP) online y a distancia que hemos diseñado, experimentado y evaluado utilizando el esquema herbartiano como herramienta principal de análisis. Mostramos la potencia de esta nueva herramienta de análisis, especialmente para emanciparse de las formas tradicionales de formación y asegurar (o por lo menos intentar) el desarrollo de las principales dialécticas del estudio: cuestión-respuesta, media-medio e individuo-colectivo. Veremos en particular muchas de las debilidades de los dispositivos experimentados, así como las potencialidades de muchos otros.
The paradigm of questioning the world in research and teaching
El paradigma del cuestionamiento del mundo en la investigación y en la enseñanza
Authors: Delgado Tomás Ángel Sierra , Almouloud Saddo Ag
Published: June 2019

EDITORIAL EM INGLÊS, ESPANHOL, fRANCÊS E pORTUGUÊS
Diseño de producción para la agroindustria hortofrutícola de pulpas congeladas, deshidratados, y/o moliendas en la región Caribe
Authors: Causado Rodriguez Edwin , Ospino Ayala Oscar José , Racedo Gutiérrez Jelibeth Paola
Published: June 2019

El sector agroindustrial hortofrutícola en Colombia se ha considerado una vía para el progreso, el desarrollo, y la paz; sin embargo, la mayoría de establecimientos procesadores de este sector carecen de un buen esquema de instalaciones, por esto, en el presente artículo se realiza una aplicación del diseño de producción a esta actividad productiva que no ha contado con muchos estudios al respecto, sobre todo en la región Caribe; para lo cual, se propone una metodología para el diseño de instalaciones de plantas agroindustriales. El resultado de esta aplicación evidenció que la planificación del diseño productivo antes de cualquier montaje de plantas, garantiza el cumplimiento de las normas gubernamentales, disminuye las perdidas por mal diseño, e incide en el mejoramiento del proceso de manufacturera de manera sustancial. Apreciándose así, que el uso de las herramientas propias de la ingeniería industrial permite el aumento competitivo en las plantas procesadoras de alimentos.
PENGARUH PRODUK BANK MUAMALAT TERHADAP PERTUMBUHAN USAHA MIKRO KECIL MENENGAH DI KOTA PALOPO
Authors: Ayyubi Mukhtaram
Published: June 2019

This research aims to know and analysis the business capital, investment and consumptive toward small micro and medium growing in Muamalat Syariah Bank Branch of Palopo, and to know and analysis between the product have dominant impact toward small, micro and medium enterprise growing in Muamalat Syariah Bank Branch of Palopo. The result of research to found that the product of Muamalat Syariah Bank such as business capital, investment and consumptive in simultaneous affected in positive and significant toward small, micro and medium enterprise growing at Palopo. And in partial the product have applied to customer as attempt to increase of small, micro and medium growing at Palopo City. Based on the result to found that the business capital have dominant affected positive and significant toward UMKM growing at Palopo. This mean the capital to give from client or customer suitable with appointment which to insurance it, would support increasing the UMKM growing
KORUPSI DALAM PERSPEKTIF FILSAFAT HUKUM ISLAM
Authors: Firmansyah Firmansyah
Published: June 2019

Act of corruption is the act Dirty, cheating and bad Judging from the positive law and legal From the legal perspective Islam faktor causes of corruption there are prayer external (opportunities , Needs ) and internal AS namely greed And its reduced intelligence spiritual (religious problem ) or word heart identifiable or in objectivation From prayer.for the future setting on the problem of corruption should be accommodated religious hearts by making anti - corruption jurisprudence, order Becoming Guidelines and Reference and Rules paled not animates positive Yang was born and penalization Right to review Performers Corruptor for the benefit considerations
IMPLEMENTASI NILAI-NILAI EKONOMI SYARIAH DI PASAR BELAWA KECAMATAN MALANGKE KABUPATEN LUWU UTARA
Authors: Kamma Hamzah , Fasiha Fasiha , Sarwia Sarwia
Published: June 2019

The purpose of this study was to determine the application of Islamic economic values in the Belawa Market, Malangke sub-district, North Luwu Regency. In this study the authors used a type of qualitative descriptive research. Data sources used are primary data sources and secondary data. Primary data obtained from interviews with traders in the Belawa Market, while secondary data sources were obtained from library studies and documents. There are also data collection techniques used through observation, interviews, and documentation. The results of the study show that sharia economic forms in the Belawa Market are those which traders are not responsible for their merchandise and do not apply fairly to their consumers so that consumers feel disadvantaged and wronged by the treatment of traders and consumers who are not comfortable in conducting transactions conducted by traders irresponsible and unfair traders. The application of Islamic economic values in the Belawa Market is not well organized due to a lack of traders' knowledge of Islamic economic values and there are still some traders who cheat in conducting transaction activities and do not pay attention to ethics in trading in accordance with Islamic law.
POLITIK EKONOMI ISLAM KOMPARASI HUKUM DAN NILAI SISTEM EKONOMI DUNIA
Authors: Sumar'in Sumar'in
Published: June 2019

The Islamic Economic Doctrine is a comparative study that looks at the fundamental principles of Islamic economics, and compares them with the economic and philosophical foundations of capitalism and Marxism. It identifies through a review of theoretical economics the structural problems that lie in the current economic order. Poverty and Inequality have increased in last two decades and the millennium development goals are still far from achieved. The research identifies that lack of an ethical foundation, unbridled pursuit of self interest in production as well as in consumption, interest based financial ad monetary system are the major problematic issues in Capitalism against which mixed economy has also shown limited effectiveness. Socialism promises to create heaven   on earth, but takes fundamental human rights and profit motive away and in the extreme case give way for an autocratic or totalitarian regime. Islamic economic system in its true sense is not present in any country. It is a blend of natural features present in Capitalism i.e. right to private property, private pursuit of economic interest, use of market forces etc. used along with some distinct features derived through Islamic economic teachings i.e. interest free economy, moral check on unbridled self-pursuit and provision of socio-economic justice to achieve the goals of Socialism as far as is naturally possible without denying individual freedom and profit motive.
PEMIKIRAN EKONOMI IBNU TAIMIYAH
Authors: Fasiha Fasiha
Published: June 2019

The development of Islamic economics can not be separated from the historical development of Islamic civilization. The study of the history of economic thought by analyzing the description of economic thinking Ibn Taymiyyah and the history of life that affect the economic thinking of Ibn Taymiyyah. According to Ibn Taymiyyah pricing by the government is good, but not absolute, because the actual prices are set by the forces of demand and supply. Another case, if the price increases caused by injustice market mechanism, the government may intervene in pricing. To achieve this purpose, it is necessary formation hisbah institutions with the aim of protecting the interests of buyers and sellers
PELAKSANAAN PERJANJIAN SEWA -MENYEWA KEBUN DI DESA POMPENGAN KECAMATAN LAMASI TIMUR TINJAUAN EKONOMI ISLAM
Authors: Yusmad H Muammar Arafat , Puspa Puspa
Published: June 2019

It is undeniable that leasing transactions are common in the community. Renting is basically permissible in Islam, because basically human beings are always constrained by limitations and shortcomings. Therefore, humans between one and the other are always bound and need each other, and renting is one of the applications of limitations that are needed by humans in social life. However, if viewed from the nature of speculative renting a garden, it means that there is no certainty whether the plantation will succeed or not at all produce in large or small quantities, then this element of uncertainty cannot be justified in Islamic law.
PERAN TIM PENGAWALAN, PENGAMANAN PEMERINTAH DAN PEMBANGUNAN DAERAH (TP4D) KEJARI PALOPO DALAM PENCEGAHAN TINDAK PIDANA KORUPSI
Authors: Mannaba Moh. Rizal
Published: June 2019

The purpose of this study was (1) to find out and analyze the effectiveness of the role of the escort team, government security and regional development (TP4D) at Palopo in preventing corruption, (2). Knowing and analyzing the factors that influence the implementation of the role of the Guardian Team, Government and Regional Development (TP4D) at Palopo in preventing corruption. The research conducted by the author is a type of descriptive research with a juridicalempirical approach is research that examines positive legal rules in order to get answers to existing problems by linking to facts or phenomena about the role of TP4D Palopo in preventing corruption. Research Results show that The implementation of Attorney Palopo's TP4D duties in the prevention of corruption has been carried out effectively, including: escorting and safeguarding the course of government and development through preventive efforts; provide legal assistance in each stage of the development program; coordinate with the Internal Government Supervisory Apparatus (APIP) to prevent irregularities; monitoring and evaluating the implementation of work and development programs.
PERANAN ARBITRASE (BASYARNAS) DALAM PENYELESAIAN SENGKETA BISNIS SYARI’AH
Authors: Siswanto Eko
Published: June 2019

Basyarnas as the agency authorized to settle business disputes Shari'ah has a very important role, including: resolving disputes with the principle of prioritizing civil peace efforts; resolving disputes over business operations using Islamic law can be resolved with the use of Islamic law; resolve the possibility of civil disputes between banks Shari'ah with customers or users of their services in particular, and among Muslims who perform civil relationships that make Islamic shari’ah as essentially in general is a genuine need real; and provide a simply and speedy settlement of disputes in civil muamalah or arising in the field of trade, industry, services and others. Basyarnas dispute settlement through confidence and security will be guaranteed for the parties to the dispute; the expertise of the arbitrators; arbitration is confidential; wisdom and sensitivity arbitrator; arbitration decisions more easily implemented than justice; rapid and cost-effective completion. The various stages of settlements, namely: a request to conduct the arbitration; Determination Arbiter; examination; peace; evidence and witnesses or experts; the end of the examination; decision making; improvement of the decision; cancellation of the decision; registration decision; implementation of the decision; and arbitration costs.
Give credit to the market: The decision not to prohibit 100 per cent loan-to-value mortgages
Authors: FitzGerald Cathal
Published: June 2019

A decision not to prohibit or limit high-risk mortgage products in Ireland in 2005 reveals the extent to which three important factors – interests, institutions, ideology – impact on information processing by decision-makers, and reveals irrationality or otherwise in the process. This article summarises the events leading up to the bad decision on 100 per cent loan-to-value (LTV) mortgages in November 2005. This case reveals the nature of the interaction between government departments, regulators and banks at a critical time before the crash, and shows how a department’s interests can interact with institutional factors, and the ideological context, to prompt poor rational and irrational information processing, and lead to a bad decision. In particular, the dominance of a market ideology which raised the threshold for what information was necessary before intervention would be made, combined with the low institutional standing of the department seeking intervention, produced a suboptimal outcome. Finally, the case provides evidence of irrationality (e.g. groupthink, herding) within institutional actors, rather than between them.
Intensity of Soccer Players’ Training Load in Small-Sided Games with Various Content Focus
Authors: Nagy Nikolas , Holienka Miroslav , Babic Matej , Michálek Jakub , Kunzmann Egon
Published: June 2019

The aim of this research was to make reference to the difference in heart rate values (HR) of soccer players in small-sided games (SSG) with various content focus. We assumed that the aim at the content in small-sided games would significantly affect the HR values of participating soccer players. The research group was comprised of players (n = 6) of the soccer club FK DAC 1904 Dunajská Streda (U15) at the age of 14 ± 0.7 years. The HR values were evaluated on the basis of collected data, which we obtained using sport testers and special software POLAR TEAM2. In order to find out the statistical significance of the difference in HR was used the One-Way ANOVA and the Bonferroni post hoc test. The level of statistical significance was set at 5 %. We found out that by the change of the small-sided game’s content focus, the internal reaction of players’ organism to training load was at different level. In the SSG3, with the emphasis on the improvement of individual’s final offensive game activity – shooting, was recorded the highest achieved HRavg value of the monitored players (181.83 ±7.11 beats.min−1). This form of the SSG was the most intense. However, there were no significant differences in HR values among the individual forms of the SSG. Our recommendation is to employ in the systematic training process small forms of small-sided games with various content focus, because by the means of it we can adequately prepare the players for the match load itself.
Validation of RAPD and ISSR Markers Used for Sex Determination in Date Palm Grown under Sudan Conditions
Authors: Mohammed Ismail A. , Mohamed Israa A.
Published: June 2019

Date palm is one of the most important economical crops in the world. Sex determination of date palm in early stage is a prerequisite for breeding and cultivation. The aim of this study is to validate RAPD and ISSR markers for sex identification of date palm genotypes grown under Sudan conditions. DNA was extracted from ten seedlings and five male and female plants using CTAB method. Eight primers, six RAPD and two ISSR primers were examined for their validation in sex determination of date palm genotypes. PCR amplification was performed using these primers. Four RAPD primers OPA02, OPJ-09, RD A02 and RD A21 were amplified male specific band with size of 1000, 1100, 1000 and 1400 pb respectively, while ISSR markers could not. The specific bands were observed clearly among all male genotypes and absent in female samples unknown samples irrespective of genotypes. Our results could be useful for sex determination of date palm sex in seedling stage and would promote date palm cultivation and production.
DNA Fingerprinting of Sex in Jojoba (Simmondsia chinensis) Grown under the Semi-arid Conditions of Sudan
Authors: Mohammed Ismail A. , Osman Fatima M. , Elsanousi Rania S. , Elhoweiris Sayeda O. , Gasim Seif M.
Published: June 2019

Jojoba cultivation and production face the challenge of establishing ways to identify the sex at early stage of plant growth. The present study was carried out to identify sex of jojoba at the seedling stage under Sudan condition. Two DNA markers, ISSR (UBC807) and RAPD (OPG-5), were used for sex identification of jojoba genotypes: two known male and females genotypes and four unknown genotypes. ISSR marker, UBC807 was successfully amplified a unique male-specific band at 1200 bp, while RAPD marker, OPG-5 could not amplify a unique band within jojoba sex. The result clearly indicates that ISSR-UBC807 marker can be used for sex identification of jojoba at seedlings stage, a finding that could make the commercial cultivation and production of jojoba possible in Sudan.