bluuebunny/crossref_metadata_2025 huggingface dataset:
A Política de Fundos no financiamento da Educação Básica
Authors: Rolim Rosana Maria Gemaque
Published: March 2021

O texto apresenta considerações acerca da política de fundos no financiamento da educação básica. Toma como parâmetro a perspectiva do direito à educação pública de qualidade e o fortalecimento desse projeto. Foi desenvolvido a partir do questionamento se a política de fundos - estratégia de financiamento da educação básica – possibilitou o fortalecimento do projeto de educação pública. Para isso, elegeu como indicador da análise o movimento das matrículas na educação básica, de 1996 a 2019. Constatou que a redistribuição dos recursos produziu dinâmicas diferentes no atendimento às matrículas entre as etapas de ensino, com retração do atendimento público e o avanço do privado, decorrentes dos limites na formatação do fundo na capacidade de financiamento das redes municipais
Black Lives Matter!: pelo reconhecimento da igualdade de direitos para a população afrodescendente
Authors: Souza Vilma Aparecida de , Silva Maria Vieira , Richter Leonice Matilde
Published: March 2021

Esta edição da Revista Educação e Políticas em Debate apresenta aos leitores o dossiê temático “Políticas educacionais de igualdade racial: concepções, reflexões e pluralidades”, organizado pelos professores doutores Cairo Mohamad Ibrahim Katrib e Astrogildo Fernandes da Silva Júnior, ambos da Faculdade de Educação da Universidade Federal de Uberlândia (FACED/UFU). Nesta edição, o dossiê se direciona às políticas educacionais de promoção da igualdade racial, a partir da discussão de reflexões teórico-metodológicas e pesquisas educacionais, sem perder de vista a interlocução com a experiência docente, cujo ponto convergente abarca o reconhecimento da diversidade sociocultural e o combate ao racismo e à discriminação.
Interstitial lung disease in systemic sclerosis (systemic scleroderma)
Authors: Ananyeva L. P. , Tyurin I. E. , Koneva O. A. , Garzanova L. A. , Lila A. M.
Published: March 2021

In systemic sclerosis (SSc), interstitial lung disease (ILD) is common (>80%) and worsens the prognosis of the disease, but severe progressive damage develops only in 8–10% of cases. Interstitial changes in the lungs occur early (within the first 3–5 years of the disease). The histological manifestations are similar to those of idiopathic ILD.

The main tool for screening and diagnosing of ILD associated with SSc is high-resolution computed tomography of the lungs, resulting data influence the choice of therapy. In most patients a relatively intact and stable forced vital capacity of the lungs is recorded for a long time, but the diffusion capacity of the lungs decreases early and steadily. Pulmonary functional tests have prognostic value.

The choice of the optimal therapy for SSc with lung lesions is based on general disease activity (the severity of inflammation and fibrosis) and the its severity, rate of progression of the disease in general and the leading pathology – interstitial pneumonia (IP) – in particular. In patients with SSc and severe or progressive IP, treatment with mycophenolate mofetil (MMF), cyclophosphamide, nintedanib, or nintedanib in combination with MMF if appropriate, should be considered. If this therapy is ineffective, rituximab may be used.
PERNIKAHAN DINI DI LERENG MERAPI DAN SUMBING
Authors: Julijanto Muhammad
Published: March 2021

This article discusses about the practice of early marriage in Selo district of   Boyolali and Kaliangkrik district of Magelang. Based on empirical research, this article argues that many people practiced early marriage in these both districts. Family tradition and out of wedlock pregnancy were two main reasons behind the practice. Some efforts are being made to improve the quality of life of people in  Selo Boyolali and Kaliangkrik Magelang such as building family quality, promoting early marriage prevention, increasing the role of community education, marriage law counseling, training and improving community skills. The involvement of community leaders in these efforts is very influential. This is indicated by the  issuance of circular letters preventing early marriage. The result is the decrease of early marriage practice in Selo and Kaliangkrik   Artikel ini membahas tentang praktik pernikahan dini yang banyak terjadi di Kecamatan Selo Boyolali dan Kecamatan Kaliangkrik Magelang. Hasil penelitian empiris menunjukkan bahwa terdapat dua faktor penting yang menyebabkan terjadinya pernikahan dini di dua kecamatan tersebut, yaitu tradisi/kebiasaan turun temurun keluarga dan hamil di luar nikah. Untuk menurunkan angka pernikahan dini ini, beberapa usaha telah dilakukan oleh pemerintah setempat seperti membangun kualitas keluarga, pencegahan pernikahan dini, peningkatan kualitas pendidikan, bimbingan pernikahan, dan peningkatan ketrampilan. Dalam usaha ini, pemimpin lokal mempunyai peranan penting dalam mempengaruhi penurunan praktik pernikahan dini. Ini diindikasikan dengan dikeluarkannya surat edaran pelarangan nikah dini oleh KUA setempat. Surat edaran ini mampu  memenurunkan angka pernikahan dini yang ada di dua kecamatan tersebut .
Five Years of India Rankings 2016 2020 an Evolutionary Study
Authors: Joorel J P Singh , Kumar Abhishek , Solanki Hiteshkumar , V Raja , Shah Dharmesh , Pradhan Pallab , Trivedi Kruti , Singh Priyanka
Published: March 2021

India Rankings i.e. National Institution Ranking Framework (NIRF) started in 2015 and completed its fifth year of yearly exercise in 2020. This article is based on evolutionary study of India Rankings. The study highlights the life cycle of India Rankings including different disciplines and their framework. It also focuses on how the framework is being matured year by year on the basis of availability of data in Institutions. There were several changes / deviations that happened due to non-availability of data or garbage data entered by the Institutes.
Estimation and Management of Performance Limiting Factors in the Development of 1 kW Peak Power Pulsed Fiber MOPA at 1550 nm
Authors: Agrawal Lalita , Bhardwaj Atul , Ganotra Dinesh , Srivastava Hari Babu
Published: March 2021

An all-fiber three-stage master oscillator power amplifier (MOPA), based on Erbium and Erbium-Ytterbium co-doped fibers, has been designed and developed. The performance of such a laser is primarily limited by amplified spontaneous emission (ASE), Yb bottlenecking, and non-linear effects. Other important factors, that need to be considered towards performance improvement, are fiber bend diameter and heat generated in the fiber. This paper describes the methodology for the estimation and management of these limiting factors for each amplifier stage. The work presented here is limited to the fibers which are commercially easily available, unlike customised Yb- free large mode area (LMA) Erbium-doped fibers, where very high peak and average powers are being reported due to the absence of Yb ASE. Presented experimental results and discussion shall be beneficial for the fiber laser amplifier designers. With suitable management, 1 kW peak power pulses of 30 ns duration at 200 kHz repetition rate have been achieved with 30 % optical efficiency. The collimated output of 6 W average power (limited by Yb ASE) with high beam quality (M2 ≈ 1.6) at 1550 nm can be employed for a variety of applications. By adding additional amplifier stages, power can be scaled further.
Kakovost življenja oseb s Pompejevo boleznijo
Authors: Halec Bine , Žunkovič Olga , Horvat Pinterić Gordana , Lorber Mateja
Published: March 2021

Uvod: Pompejeva bolezen spada med zelo redke prirojene metabolne bolezni; zanjo je značilen primanjkljaj ali odsotnost encima alfa-glukozidaza. Kopičenje glikogena v mišičnih celicah posledično privede do slabšanja mišične moči, močnih bolečin ter napredujočih težav z dihanjem. Namen raziskave je bil ugotoviti vpliv bolezni na kakovost življenja in negovalne probleme, ki se pri takšnem pacientu pojavijo.Metode: Uporabljena je bila kvalitativna metodologija raziskovanja. Izveden je bil delno strukturiran intervju s pacientko, ki ima diagnosticirano Pompejevo bolezen. Intervju smo posneli, dobesedno zapisali in analizirali z metodo analize besedila.Rezultati: Ugotovljeno je bilo, da je Pompejeva bolezen močno vplivala na kakovost življenja pacientke. Z metodo analize besedila je bilo identificiranih pet podkategorij: sprejetje bolezni; pomoč bližnjih; težave zaradi bolezni; izvajanje vsakodnevnih aktivnosti in zdravljenje. Podkategorije so bile nato združene v glavnokategorijo, poimenovano »vpliv na kakovost življenja«. Prav tako je bilo izpostavljenih sedem negovalnih problemov: strah, žalost, oteženo dihanje, bolečina, obstipacija, utrujenost, nevarnost za padec.Diskusija in zaključek: Pompejeva bolezen močno spremeni kakovost življenja pacienta, saj se slednji srečuje s številnimi težavami na različnih področjih življenja. Za zagotavljanje višje kakovosti življenja in lažje izvajanje vsakodnevnih aktivnosti je pomembno, da pacient s Pompejevo boleznijo s strani bližnjih in zdravstvenih delavcev prejme ustrezno pomoč in podporo.
Włoskie inicjacje Aleksandra Wata
Authors: Pietrych Krystyna
Published: March 2021

The article presents the stages of Aleksander Wat’s first journey to Italy in 1949 – starting from Venice, through Florence and Rome, finishing in Naples and Capri. Most of all, the article interprets the poetic records of the places visited by the poet and his impressions written down in letters. As a result, what the journey to Italy becomes for Wat is not only a discovery of the beauty of landscape and the plenty of art, but, most importantly, an experience of physical contact with the Mediterranean land, an initiation into the fascinating witnessing of the incarnation of cultural tradition into a visible landscape, a sensual initiation into the legacy of the Mediterranean. The coda of the text is his unexpected reminiscence from the first journey to Italy recorded in a social realist drama.
Rotors with a novel structure for enhanced follow-up dynamic mixing
Authors: Wen Xin , Ding Yumei , Shi Meinong , Yan Hua , Zuo Xiahua , Yang Weimin , Yang Yousheng , Ding Shikang
Published: March 2021

Nowadays, dynamic mixers are widely used in industry. But dynamic mixers have problems like low mixing efficiency and high mixing resistance. Therefore, many scholars are committed to improving the rotor inside the dynamic mixer to improve its working performance. In this paper, a new structure of spiral rotor with chamfer and perforation was designed for promoting the performance of the dynamic mixing equipment. We measured the pH value to find which rotor’s working performance is better. On this basis, a numerical simulation was conducted on the mixing angle of the two-phase fluid to explore the best working environment of the dynamic mixer. Experimental studies proved that the mixing effect of the new structure rotor was better. The simulation results showed that the mixing effect of the two-phase flow was better when it merged at 135°.
The archaeology of complexity and cosmopolitanism in medieval Ethiopia: an introduction
Authors: Insoll Timothy
Published: March 2021

Archaeology increasingly attests the complex and cosmopolitan nature of societies in medieval Ethiopia (c. seventh to early eighteenth centuries AD). Without negating the existence of relations of dominance and periods of isolation, key emergent themes of such research are pluralism and interaction. Four religious traditions are relevant to this theme: Islam, Judaism, Christianity and Indigenous religions. This article introduces a special section of contributions on medieval Ethiopia and sets the scheme by highlighting the temporality of cosmopolitanism as episodic rather than continuous. The following articles address varied aspects of this cosmopolitanism, identifying issues of general relevance for studies of the archaeology of religion, as well as the need for further research in Ethiopia.
Stress Corrosion Cracking in Austenitic Stainless Steels in Reactor Primary Water–High Purity Oxidizing and in Supercritical Conditions
Authors: Das Annesha , Roychowdhury Supratik , Kain Vivekanand
Published: March 2021

Austenitic stainless steels (SS) commonly used in the primary circuit of light water reactors (LWRs) have excellent corrosion resistance in demineralized (DM) water at high temperature (290°C–330°C) and pressure (7.4 MPa for boiling water reactor [BWR], 16 MPa for pressurized water reactor [PWR]). Radiolysis of primary DM water in BWR forms 200–300 ppb of oxidizing species (normal water chemistry [NWC]), which elevates the electrochemical potential of the SS from −300 to −600 mVSHE (mV with standard hydrogen electrode) when dissolved oxygen is 10–20 ppb to +100 to +200 mVSHE. Neutron irradiation of SS further induces metallurgical and microstructural changes, which compromises corrosion resistance. Thus, radiation makes BWR (NWC) environment hostile, causing extensive irradiation-assisted stress corrosion cracking (same as intergranular stress corrosion cracking [IGSCC]) in austenitic SS. IGSCC occurs in both sensitized (grain boundary chromium depletion) and nonsensitized conditions (strain-hardened region in base metal immediately adjacent to the weld fusion zone) and is a generic problem. IGSCC in BWR can be mitigated by hydrogen addition in water (hydrogen water chemistry [HWC]). BWR-HWC has limitations and is ineffective where boiling occurs. IGSCC of SS in PWR is limited because hydrogen addition in primary water suppresses radiolysis though the formation of aggressive environment in low-flow occluded regions can cause IGSCC in SS. Increasing demand for economic power has led to the primary environment in nuclear reactors to become hostile. Conceptual supercritical water reactor (SCWR) will use DM water at 500°C–600°C and 25 MPa, which is extreme for conventional LWR materials. IGSCC in austenitic SS and nickel-based alloys occurs in both oxidizing and reducing SCWR conditions, which can be further exacerbated by radiation. This article reviews how benign primary DM water becomes hostile in LWRs and extreme in SCWR conditions, causing SCC to be a generic problem in austenitic alloys.
Mechanism of Pacemaker Activity in Zebrafish DC2/4 Dopaminergic Neurons
Authors: Ilin Vladimir A. , Bai Qing , Watson Alan M. , Volgushev Maxim , Burton Edward A.
Published: March 2021

Zebrafish models are used increasingly to study the molecular pathogenesis of Parkinson's disease (PD), owing to the extensive array of techniques available for their experimental manipulation and analysis. The ascending dopaminergic projection from the posterior tuberculum (TPp; diencephalic populations DC2 and DC4) to the subpallium is considered the zebrafish correlate of the mammalian nigrostriatal projection, but little is known about the neurophysiology of zebrafish DC2/4 neurons. This is an important knowledge gap, because autonomous activity in mammalian substantia nigra (SNc) dopaminergic neurons contributes to their vulnerability in PD models. Using a new transgenic zebrafish line to label living dopaminergic neurons, and a novel brain slice preparation, we conducted whole-cell patch clamp recordings of DC2/4 neurons from adult zebrafish of both sexes. Zebrafish DC2/4 neurons share many physiological properties with mammalian dopaminergic neurons, including the cell-autonomous generation of action potentials. However, in contrast to mammalian dopaminergic neurons, the pacemaker driving intrinsic rhythmic activity in zebrafish DC2/4 neurons does not involve calcium conductances, hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, or sodium leak currents. Instead, voltage clamp recordings and computational models show that interactions between three components – a small, predominantly potassium, leak conductance, voltage-gated sodium channels, and voltage-gated potassium channels – are sufficient for pacemaker activity in zebrafish DC2/4 neurons. These results contribute to understanding the comparative physiology of the dopaminergic system and provide a conceptual basis for interpreting data derived from zebrafish PD models. The findings further suggest new experimental opportunities to address the role of dopaminergic pacemaker activity in the pathogenesis of PD.

SIGNIFICANCE STATEMENTPosterior tuberculum (TPp) DC2/4 dopaminergic neurons are considered the zebrafish correlate of mammalian substantia nigra (SNc) neurons, whose degeneration causes the motor signs of Parkinson's disease (PD). Our study shows that DC2/4 and SNc neurons share a number of electrophysiological properties, including depolarized membrane potential, high input resistance, and continual, cell-autonomous pacemaker activity, that strengthen the basis for the increasing use of zebrafish models to study the molecular pathogenesis of PD. The mechanisms driving pacemaker activity differ between DC2/4 and SNc neurons, providing: (1) experimental opportunities to dissociate the contributions of intrinsic activity and underlying pacemaker currents to pathogenesis; and (2) essential information for the design and interpretation of studies using zebrafish PD models.
Striatal Direct Pathway Targets Npas1+Pallidal Neurons
Authors: Cui Qiaoling , Du Xixun , Chang Isaac Y. M. , Pamukcu Arin , Lilascharoen Varoth , Berceau Brianna L. , García Daniela , Hong Darius , Chon Uree , Narayanan Ahana , Kim Yongsoo , Lim Byung Kook , Chan C. Savio
Published: March 2021

The classic basal ganglia circuit model asserts a complete segregation of the two striatal output pathways. Empirical data argue that, in addition to indirect-pathway striatal projection neurons (iSPNs), direct-pathway striatal projection neurons (dSPNs) innervate the external globus pallidus (GPe). However, the functions of the latter were not known. In this study, we interrogated the organization principles of striatopallidal projections and their roles in full-body movement in mice (both males and females). In contrast to the canonical motor-promoting response of dSPNs in the dorsomedial striatum (DMSdSPNs), optogenetic stimulation of dSPNs in the dorsolateral striatum (DLSdSPNs) suppressed locomotion. Circuit analyses revealed that dSPNs selectively target Npas1+neurons in the GPe. In a chronic 6-hydroxydopamine lesion model of Parkinson's disease, the dSPN-Npas1+projection was dramatically strengthened. AsDLSdSPN-Npas1+projection suppresses movement, the enhancement of this projection represents a circuit mechanism for the hypokinetic symptoms of Parkinson's disease that has not been previously considered. In sum, our results suggest that dSPN input to the GPe is a critical circuit component that is involved in the regulation of movement in both healthy and parkinsonian states.

SIGNIFICANCE STATEMENTIn the classic basal ganglia model, the striatum is described as a divergent structure: it controls motor and adaptive functions through two segregated, opposing output streams. However, the experimental results that show the projection from direct-pathway neurons to the external pallidum have been largely ignored. Here, we showed that this striatopallidal subpathway targets a select subset of neurons in the external pallidum and is motor-suppressing. We found that this subpathway undergoes changes in a Parkinson's disease model. In particular, our results suggest that the increase in strength of this subpathway contributes to the slowness or reduced movements observed in Parkinson's disease.
Functional Microstructure of CaV-Mediated Calcium Signaling in the Axon Initial Segment
Authors: Lipkin Anna M. , Cunniff Margaret M. , Spratt Perry W. E. , Lemke Stefan M. , Bender Kevin J.
Published: March 2021

The axon initial segment (AIS) is a specialized neuronal compartment in which synaptic input is converted into action potential (AP) output. This process is supported by a diverse complement of sodium, potassium, and calcium channels (CaV). Different classes of sodium and potassium channels are scaffolded at specific sites within the AIS, conferring unique functions, but how calcium channels are functionally distributed within the AIS is unclear. Here, we use conventional two-photon laser scanning and diffraction-limited, high-speed spot two-photon imaging to resolve AP-evoked calcium dynamics in the AIS with high spatiotemporal resolution. In mouse layer 5 prefrontal pyramidal neurons, calcium influx was mediated by a mix of CaV2 and CaV3 channels that differentially localized to discrete regions. CaV3 functionally localized to produce nanodomain hotspots of calcium influx that coupled to ryanodine-sensitive stores, whereas CaV2 localized to non-hotspot regions. Thus, different pools of CaVs appear to play distinct roles in AIS function.

SIGNIFICANCE STATEMENTThe axon initial segment (AIS) is the site where synaptic input is transformed into action potential (AP) output. It achieves this function through a diverse complement of sodium, potassium, and calcium channels (CaV). While the localization and function of sodium channels and potassium channels at the AIS is well described, less is known about the functional distribution of CaVs. We used high-speed two-photon imaging to understand activity-dependent calcium dynamics in the AIS of mouse neocortical pyramidal neurons. Surprisingly, we found that calcium influx occurred in two distinct domains: CaV3 generates hotspot regions of calcium influx coupled to calcium stores, whereas CaV2 channels underlie diffuse calcium influx between hotspots. Therefore, different CaVclasses localize to distinct AIS subdomains, possibly regulating distinct cellular processes.
Considering Instructional Approach & Question Design with the Hardy-Weinberg Principle
Authors: Driver Robert J. , McRae Susan B.
Published: March 2021

The Hardy-Weinberg principle (HWP) is an application of the binomial expansion theorem that is foundational to the field of population genetics. Because of the important history of the HWP in answering how variation is preserved during evolution, and the ability of Hardy-Weinberg equilibrium (HWE) to detect natural and sexual selection acting on a trait, the HWP is a staple of the introductory biology undergraduate curriculum in the United States. Introductory courses often cover a wide range of topics in ecology and evolution, and it is important that students have enough time during the semester to grasp the foundations of population genetics. At the same time, information needs to be presented clearly to ensure that the student gains a correct understanding of the HWP. This article discusses the importance of the HWP to undergraduate education in biology and describes misconceptions from the instructor’s perspective. These misconceptions are pervasive and risk undermining a proper understanding of the HWP. We provide examples adapted from university- and AP-level standardized tests.
Five Letters to Georgia O’Keeffe
Authors: Simmons Jake
Published: March 2021

In her lifetime, US American painter Georgia O’Keeffe (1887–1986) wrote thousands of letters to those closest to her. However, she relied on painting as her primary public voice. This essay takes the form of five letters, composed through posthumanist performative writing,1 addressed to O’Keeffe. I work through the process of experiencing the death of my father in a material landscape as it was painted by O’Keeffe. The southwestern landscapes O’Keeffe painted were the same landscapes in which my father and I negotiated material relations to live a life of what Donna Haraway calls “significant otherness.”2
Developing Palm Oil Inventory Control System Using Ms Excel Macro
Authors: Ismail Siti Zubaidah , Abdullah Al-Hadi Abdulsalam Khaled
Published: March 2021

The palm oil sector is just one of the popular sectors in Malaysia that offer one of the highest exports to Malaysia's economy. This study handles the research study of inventory control for Malaysian palm oil plantation. The existing inventory control cannot be running smoothly when the inventory are managed in different user interface systems which is by utilizing manual inventory control like Microsoft Excel and handwriting documents. Data collection was gathered with the targeted respondents, they are core members of the management team who have a great experience as well as understanding of their inventory system. In order to make PSS inventory control much easier as well as organized, an inventory application system is developed utilizing MS Excel Macro. The outcomes of this research study are a computerized supply control system that beneficial, crucial, and also much better substitute for a hand-operated administration system and quick handling.
Kryzys gospodarczy w latach 1979-1982 zwiastunem upadku PRL
Authors:   Szkoła Główna Handlowa w Warszawie, Kaliński Janusz
Published: March 2021

Purpose – The article points to the important role of the economic crisis of 1979-1982 in the process of the collapse of the political and economic system imposed on Poland after 1944. Research method – The paper written on the basis of the economic history method, makes an extensive use of the available literature on the subject, the published documents of state authorities, archives, statistics and legal acts. Results – The Author proves that the end of the seventies, which is generally considered the best period in the economy of the People’s Republic of Poland, brought about a crisis and a recession lasting four years. Their causes lay in the erroneous economic policy of the Edward Gierek’s team and in the deformations of the economy management system stemming from older times. The crisis of 1979-1982 showed that the centrally planned economy system in Poland had exhausted its possibilities and even external capital injections were not able to compensate for the low efficiency and the wastafulness in “the real socialism”. Originality /value – The article is a contribution to the still lively, often fueled by contradictory arguments, discussion on the fall of the Polish People’s Republic.
Przedsiębiorcy i przedsiębiorczość a recesja transformacyjna w Polsce po 1989 roku
Authors:   Uniwersytet Kazimierza Wielkiego w Bydgoszczy, Kamosiński Sławomir
Published: March 2021

Purpose – The “explosion” of entrepreneurship observed in Poland after 1989 and continuing throughout the years with varied intensity is a global phenomenon. Most importantly, the entrepreneurship freed the accumulated resources of human energy that had been dormant in the years of the People’s Republic. Research method – For the study presented herein the method of analysis of available statistical data dating back to the years 1989-1992, and of source materials in the form of memories of entrepreneurs operating in that period was applied. Results – The objective of research as such proves that, even though the economically active entities did not fall within the frame of the concept of “entrepreneurs” proposed by Joseph Schumpeter, they were the one who initiated the dynamic changes in the Polish economy after 1989, often referred to as the “creative destruction”. Considering the above, the development of the resources of entrepreneurship observed at those times took place during the transformational recession that occurred in 1990-1991. In its classical form, the Schumpeterian phenomenon of using recession as a springboard to business success by active individuals was observed. Originality / value / implications / recommendations – In the literature on the subject, there is a lively and inspiring discussion about the transformational recession and its social consequences. Less frequently, scientists point to the link between the explosion of entrepreneurship after 1989 and the transformational recession. The article deals with this research problem from the microeconomic perspective. It reveals the efforts of entrepreneurs to build their own businesses and indicates their contribution to alleviating the social consequences of the transformational recession.
An aggressive and expanded phenotype in a kindred with a c.57delG SDHD mutation
Authors: Caetano Celina , Stroop Jennifer , Forouhar Faripour , Orsey Andrea , Malchoff Carl
Published: March 2021

Familial paraganglioma syndrome type 1 (PGL-1) is maternally imprinted, caused by SDHD mutations on the paternally inherited allele, and presents with paragangliomas and pheochromocytomas that are usually benign. We describe a kindred with a germline c.57delG SDHD mutation that demonstrates an aggressive and possibly expanded phenotype. Eight individuals across four generations were heterozygous for the c.57delG SDHD mutation. The three with known paternal inheritance were clinically affected. The aggressive phenotype was manifested by a neck paraganglioma with distant metastases, and to a lesser degree a neck paraganglioma infiltrating into local connective tissue and a pheochromocytoma presenting at age 8 y. A pulmonary capillary hemangioma may expand the SDHD phenotype. We conclude that the c.57delG SDHD mutation may confer a more aggressive and possibly expanded phenotype than other SDHD mutations.

Learning points:

The c.57delG SDHD mutation may confer a more aggressive phenotype than other mutations associated with familial paraganglioma syndrome type 1.

A capillary hemangioma, a component of other pseudohypoxia states, was observed in the lung of a single member of the c.57delG SDHD kindred.

This report supports the hypothesis of others that mutations found near the beginning of the SDHD open reading frame are more likely to demonstrate an aggressive phenotype.
O PAPEL DA AUSTERIDADE NA SAÍDA DA CRISE DOS PAÍSES PERIFÉRICOS DA EUROZONA: UNHA ANÁLISE DENDE A POLÍTICA ECONÓMICA
Authors: Menéndez Blanco Juan Manuel , Alonso González Luis Alberto , Moreno Gallego Luis Santiago
Published: March 2021

O obxectivo principal deste artigo é analizar o papel da política de austeridade na saída dacrise dos países que forman a periferia da eurozona a partir dun marco de análise no quese inclúen os posibles escenarios de política económica resultantes de combinar aausteridade fiscal coa devaluación interna. A partir da análise dos escenarios viables, nocontexto institucional actual da eurozona, conclúese que a supervivencia do euro a curto emedio prazo se dará nun escenario difuso –entre o denominado escenario Werner-Sinn eo calificado como Mezzogiorno- no que non se restaurará nin a competitividade dos paísesda periferia nin un crecemento satisfactorio que elimine o desemprego.
IMPACTO DA TRIBUTACIÓN AUTONÓMICA SOBRE EMISIÓNS. UNHA PERSPECTIVA MICROECONÓMICA
Authors: VALLES-GIMENEZ Jaime , ROMÁN-ASO Juan A.
Published: March 2021

O obxectivo deste traballo é analizar o impacto da tributación autonómica sobreemisións para dúas mostras de 100 instalacións industriais en España. A primeira estácomposta polos fluxos anuais de dióxido de carbono, namentres que a segunda recolle osde óxidos de nitróxeno e de azufre, as dúas para o período 2001-2011. A implementaciónda política fiscal debe estar orientada a internalizar o dano ambiental causado polasemisións. Porén, os resultados suxiren que a efectividade da tributación autonómica é moilimitada, debido entre outras causas, ao inadecuado deseño tributario. Ademais, avalíase oefecto doutros factores sobre a evolución da contaminación industrial, particularmente dosistema de intercambio de permisos.
Sistem Informasi Sociogram untuk Meningkatkan Kualitas Pelatihan Pelajar Islam Indonesia
Authors: Saukani Ahmad Fakri
Published: March 2021

Pelajar Islam Indonesia (PII) adalah organisasi masyarakat di bidang pembelajaran, keislaman dan keindonesiaan dan sebagai organisasi kader, PII memerlukan proses pelatihan, kursus dan ilmiah untuk meningkatkan kuantitas dan kualitas anggotanya. Dalam pelatihan PII memiliki sistem penilaian menggunakan sociogram. Sociogram adalah kumpulan grafik dengan nilai pengamatan sosial dengan menggunakan metode sosiometri. PII memiliki tiga tingkat pelatihan yaitu Basic, Intermediate dan Advance. Proses penilaian peserta pelatihan dilakukan melalui beberapa tahap pendaftaran, wawancara, divisi lokal, penentuan lokal, laporan penilaian dan kemajuan lokal. Dalam setiap proses sociogram mensyaratkan seluruh data untuk diproses. Namun, PII masih menggunakan secara manual dan tidak ada keberlanjutan dan sinkronisasi data sehingga sering terjadi kehilangan data dan proses yang panjang dalam mempresentasikan data sehingga menghasilkan waktu lama dalam pengambilan keputusan dalam penanganan pelatihan. Penelitian ini bertujuan untuk mendesain dan membuat sistem informasi yang mampu mengendalikan asesmen informasi pelatihan secara efektif dan cepat. Metode yang penulis gunakan adalah pengembangan sistem RAD (Rapid Application Development) sebagai model pengembangan sistem dan Unified Modeling Language (UML) sebagai alat yang digunakan dan Java dan PHP sebagai bahasa pemrograman. Hasil penelitian ini adalah sistem informasi sociogram pelatihan yang dapat mengotomatisasi penilaian dan dapat membantu PII dalam melakukan pengelolaan penilaian partisipasi pelatihan.
Crossword puzzles versus Student-Led Objective Tutorials (SLOT) as innovative pedagogies in undergraduate medical education
Authors: J Shenoy Dr. Preethi , R Rao Dr. Rashmi
Published: March 2021

AIMS: Small group teaching in Pharmacology offers an effective platform to encourage interaction amongst peers and self-directed learning. The present study is an attempt to assess and compare the effectiveness and perception of students on two different pedagogical methods: Crossword puzzles and Student Led Objective Tutorials (SLOT).METHODS: Second year undergraduate students who gave their informed consent were divided randomly into two groups: one which received crossword puzzle as a teaching learning method and the other had SLOT during which the students conducted an interactive quiz with multiple choice questions prepared by themselves. The students’ perceptions were recorded using a self-administered questionnaire. One week later, a unit test was conducted for both the groups and the performance of the students was compared. Statistical analysis was done using independent Student’s T test with SPSS version 15.0.RESULTS: Analyses revealed a statistical significant difference (P<0.001) between the mean marks obtained in the SLOT group (n= 74; 6.5±3.8) and the marks obtained in the crossword group (n= 87; 4.2±2.9), with the students in the tutorial group performing better. The students opined that SLOT sessions helped them to understand Pharmacology better whereas crossword sessions enabled them to memorize the names of the drugs.CONCLUSION: The present study revealed that SLOT sessions fared better compared to the crossword puzzles in terms of improving the students’ test scores. It fostered teamwork, self-directed learning skills and critical thinking. Crossword puzzles make the session more student friendly as it is fun and engaging but a careful design is inevitable as it may fail to test in-depth learning in students.
Problems of Health Protection of Students with Health Limitations in Educational Institutions of the Russian Federation
Authors: Lazurenko Svetlana B. , Solovyova Tatiana A. , Terletskaya Rimma N. , Konova Svetlana R.
Published: March 2021

Introduction. The current legal framework for the education of children with health limitations was created after the conceptual provisions and international acts to ensure equal children’s opportunities and access to free educational services without any type of discrimination. Regulatory documents contain the general rules for organization of educational activities and medical support in an educational institution, without specific recommendations for health strengthening and preservation of children with health limitations, taking into account the nature and severity of the disorder, as well as the combination thereof, which is a separate urgent state problem. This study was initiated to analyze the current situation with health protection of special needs children in educational institutions. The detection of organizational difficulties and legal restraints will allow to determine the remedial measures and prepare the proposals for the improvement of the educational system.
Materials and Methods. The content analysis of the applicable regulatory legal documents of the Ministry of Health, the Ministry of Education and Science of the Russian Federation between 2012–2020 revealed urgent problems pertinent to the enforcement of legislative initiatives in the field of education and health protection of students with health limitations in various educational environments.
Results. The study confirmed the hypothesis of the variability of the current organizational problems regarding health strengthening and preservation of students in an educational organization, including the weak legal and regulatory framework. The health-preserving environment of an educational organization is proved to have a combination of factors: availability of special educational and technical equipment to meet special educational needs of students, taking into account the severity of the physical dysfunction; the compliance of the tightness of timetable, number of lessons and the educational load with children’s health state and individual psychological capabilities; availability of separate rest and restoration rooms; availability of up-to-date rehabilitation equipment for health strengthening of children with health limitations in the educational institution’s environment; staffing with teachers and medical specialists who are aware of modern technologies of handling children with health limitations.
Discussion and Conclusion. The study results can be facilitative of the development of the system of monitoring during the organization of the educational process and the variability of health protection conditions for students with health limitations in an educational organization as the method of prompt detection and elimination of adverse factors and, hence, mitigation of social risks and solving of one of the priority state tasks.
The Islamic Education for Single Parent's Family: A Case study in Karaban Jaya
Authors: Ubabuddin Ubabuddin , Supriyatno Triyo , Nuraini Nuraini
Published: March 2021

Everyone craves having family integrity. Because the integrity of the family makes it easy to share roles between fathers and mothers both in earning a living or doing household chores including the obligation to educate their children. But in reality, many find all these roles to be borne by one person or called a single parent, could be a father or mother. Usually it happens because of separation due to divorce or death of one of them, thus making the responsibility of raising all their children more difficult. For children, family (both parents) is the main environment they need. So from that family the parents can provide better protection and education for their future life provisions. The obligation of parents as mentioned in the Qur'an is to protect themselves and their families from the fires of hell. Then the family should become a madrasa in introducing Islamic education. As an educator in the family, parents must have the expertise and art of educating, one of the skills that must be mastered is the method. There are several methods that families can use in educating their children. This research focuses: how is the pattern of single parent care in the perspective of Islamic education to children in Karaban Jaya . The research method is qualitative with a case study approach. The results showed that parenting to educate children in single parent families in Keraban Jaya Village was by example, giving advice, motivation, and giving attention and supervision to children from young to teenagers. While the values of Islamic education taught include strengthening monotheism, worship, moral or moral cultivation, forming mentality and applying discipline or control.
Competência midiática em crianças de 9 a 12 anos em cenários brasileiros
Authors: Silva Márcia Barbosa da , Borges Gabriela , Fantin Mônica , Pimenta Maria Alzira Almeida , Aguaded Ignácio
Published: March 2021

Resumo Este artigo apresenta os resultados da pesquisa “Competências midiáticas em cenários brasileiros e euroamericanos”, que teve como objetivo conhecer os níveis de competência midiática de crianças de 9 a 12 anos para que pesquisadores, formadores e decisores políticos possam atuar para promover o seu desenvolvimento. Foi realizada pela equipe brasileira da Red Interuniversitaria Euroamericana de Investigación en Competencias Mediáticas para La Ciudadanía (ALFAMED) e os dados coletados por meio de questionários aplicados em cinco regiões brasileiras. Os resultados indicam que a competência midiática, especialmente as dimensões processos de interação e ideologia e valores, ainda estão pouco desenvolvida, indicando a necessidade e a urgência de atenção de professores e especialistas.
A política externa brasileira do governo Lula da Silva (2003-2010) nas páginas de CartaCapital e Veja: um estudo comparativo
Authors: Ferreira Túlio Sérgio Henriques , Cunha Ester Almeida Carneiro da
Published: March 2021

Resumo O artigo compara o tratamento da Política Externa Brasileira (PEB) nos semanários Veja e CartaCapital durante os dois mandatos presidenciais de Luís Inácio Lula da Silva (2003-2010). Analisou-se, qualitativa e quantitativamente, cinco grupos temáticos relacionados à PEB com o intuito de contribuir para adensar os estudos sobre meios de comunicação e política externa no Brasil. Assim, em consonância com as abordagens da Análise de Política Externa (APE) e considerando a mútua influência entre mídia, opinião pública e processos políticos, ressaltou-se o papel dos meios de comunicação como ator político. Demonstrou-se, assim, a diferença no tratamento do tema nos dois semanários, testando-se a hipótese de que a divergência explícita das linhas editoriais resultaria em contrastes na cobertura do assunto.
Um ensaio teórico sobre a influência da Teoria da Troca Social e da Co-criação de Valor no Crowdfunding
Authors: Schmitt Camila da Silva , Petroll Martin de La Martiniere
Published: March 2021

Resumo O presente ensaio teórico investigou o fenômeno do crowdfunding a partir da Teoria da Troca Social e da Co-criação de Valor no intuito de estabelecer proposições de pesquisas futuras. Percebeu-se que crowdfunding apresenta dinâmicas de co-criação em seus processos, onde os potenciais apoiadores - crowdfunders - envolvidos trabalham em estreita colaboração com o empresário de forma cooperativa, participando ativamente do desenvolvimento do projeto instaurado com feedbacks. Notou-se a plataforma crowdfunding como intermediário que facilita a interação repetida entre o proponente e apoiadores, criando valor não só financeiro. Mostrou que a criação e troca de novos conhecimentos na fase de inovação gera benefícios não financeiros ao projeto, uma vez que ganha a possibilidade de adaptar a proposta de valor ao mercado sem a necessidade de dispendiosas pesquisas. Conclui-se apresentando proposições de futuras pesquisas, como: concentrar esforços para analisar o conteúdo específico trabalhado em projetos bem-sucedidos de crowdfunding e compreender como pode auxiliar em estratégias de reciprocidade no contexto de troca social e co-criação de valor.
Práticas comunicativas, mídias e tecnologias: estudos cruzados entre Brasil e Angola
Authors: Moura Flávia de Almeida , Araújo Ed Wilson Ferreira
Published: March 2021

Resumo Apresentamos, neste artigo, pontos de comparação entre situações estudadas no estado do Maranhão, Brasil, e em três províncias do Sul de Angola: Huambo, Huíla e Benguela. Em ambos os casos, identificamos a coexistência de práticas comunicativas arcaicas, tradicionais e também a utilização de novas tecnologias, como o caso do uso da internet e das redes sociais digitais. Para a análise e interpretação dos casos, utilizamos o arcabouço teórico e metodológico proposto por autores dos estudos culturais, como Williams (2016) e Hall (2013), além de Thompson (2013) e García Canclini (2008). Percebemos, a partir dos casos analisados, que as relações entre tradição e modernidade e de tempo e espaço, por exemplo, são apropriadas pelos sujeitos visando dar conta de suas práticas cotidianas, que podem ou não ser pautadas pela lógica das mídias.
Análise da cobertura de sites jornalísticos da América do Sul, Europa e Ásia sobre os povos indígenas atingidos pela UHE Belo Monte
Authors: Paes Renata da Cruz , Sarmento Priscila Sanjuan de Medeiros , Pontes Altem Nascimento
Published: March 2021

Resumo Ao surgirem as primeiras repercussões da construção da Usina Hidrelétrica (UHE) Belo Monte, os povos indígenas se manifestaram continuamente contra o empreendimento. A imprensa acompanhou tanto o andamento das obras da Usina quanto as manifestações dos povos indígenas brasileiros em recusa à Usina. Diante disso, a pesquisa almeja investigar a visibilidade e representação desses povos em sites jornalísticos de maior circulação no Brasil e em outros 12 países estrangeiros. A amostragem se constitui de 54 matérias jornalísticas, publicadas entre 2005 a 2017. Por meio da Análise de Conteúdo (AC) de Bardin (1977), os resultados revelaram que os povos indígenas são descritos pelos jornais como “invasores” e “de menor capacidade”. Os jornais estrangeiros deram mais abertura a fala dos povos indígenas contra a UHE Belo Monte, do que os jornais brasileiros, que priorizaram o discurso do governo e dos interesses políticos.
O presente como tempo da tradição: a poesia de cordel contemporânea do Maestro Rafael Brito
Authors: Fonseca Maria Gislene Carvalho
Published: March 2021

Resumo Este trabalho é uma proposta inicial sobre o tema do presente na discussão da tradição, a partir da reflexão sobre a poesia de cordel, olhando para o trabalho do Maestro Rafael Brito, poeta de Fortaleza-CE. Rafael é jovem, escreve diversos tipos de poesia, e é mais conhecido por sua produção de cordel, à qual ele se refere de modos “tradicionais”, performando-a com a utilização de recursos midiáticos do presente. Discutimos a ideia de tradição, tradições e tradicionalidade a partir das propostas sobre narrativa de Ricoeur (2010) e analisamos o trabalho de Rafael través de entrevistas e do conteúdo de seu blog na Internet. Observamos que o Maestro é visto como uma promessa de futuro deste cordel “tradicional”, ainda que traga inovações para a historiografia da poesia. Mesmo assim, permanece distante das transformações e de embates políticos que desestabilizariam as narrativas oficiais que reivindicam tradições imutáveis.
O DEBATE SOBRE O ABORTO NAS CÂMARAS DOS DEPUTADOS DO BRASIL E DO URUGUAI (1985-2016)
Authors: Silva Luis Gustavo Teixeira da
Published: March 2021

O objetivo deste texto é analisar e comparar o debate legislativo sobre o aborto realizado no Brasil e no Uruguai. Para realizar esta investigação, utilizamos como metodologia de pesquisa a análise de todos os discursos proferidos na Câmara dos Deputados do Brasil e na Câmara de Representantes do Uruguai, entre os anos de 1985 e 2016. A comparação entre esses países é relevante por serem casos opostos no tocante ao tratamento dos direitos reprodutivos das mulheres. O Uruguai se tornou o único país da região, em período recente, a aprovar uma legislação para descriminalizar da interrupção voluntária da gravidez. Já no Brasil verifica-se a ascensão de forças políticas, sociais e religiosas conservadoras, as quais são, em grande medida, responsáveis por conduzir de modo regressivo a discussão sobre o aborto no Poder Legislativo. Nesse sentido, propomos examinar as posições em disputa e, por meio dos dados, apresentar indicadores para explicar esses distintos cenários.
Modelagem da vegetação aquática em estudos de dinâmica dos fluidos computacional
Authors: Yamasaki Taís Natsumi , Lima Paulo Henrique Silva de , Xavier Manoel Lucas Machado , Janzen Johannes Gérson
Published: March 2021

RESUMO O objetivo deste trabalho foi apresentar, por meio da técnica dinâmica dos fluidos computacional (CFD), dois métodos utilizados nas representações conceitual e física da vegetação em meio aquático: meio poroso e elementos geométricos simplificados. Três estudos de caso, que incluem um wetland flutuante e manchas de vegetação, exemplificam a aplicação dos métodos, mostrando suas vantagens e desvantagens. Nas etapas da geometria e da malha, a representação da vegetação como meio poroso é mais simples, prática e rápida do que a da vegetação como elementos geométricos simplificados. Porém, na parte da modelagem das equações, o método do meio poroso não consegue capturar os processos de mistura no interior da vegetação, enquanto o método dos elementos geométricos simplificados consegue.