bluuebunny/crossref_metadata_2025 huggingface dataset:
Jihad.cz: Interpreting Jihad, Sexual Jihad and Demographic Jihad in the Czech Anti-Islamic Milieu
Authors: Vala Tadeáš
Published: December 2021

In the last 10 years, we have seen an increased frequency of fear and criticism of Islam and Muslims in the Czech media scene. Even though the percentage of Muslims in the Czech Republic is tiny (approx. estimate is 0.2%), there are active groups and movements in the country that seek to stop the spread of Islam in the Czech Republic, and the discussion of threats from Muslims routinely permeates political statements. A very common argumentation of Czech anti-Islamic claims uses the presentation of jihad as evidence of the danger that threatens the Western world from Muslims. The most widespread understanding of this phenomenon still presents jihad as armed violence against non-Muslims, which is supposed to be clear evidence of the warlike and violent nature of Islam. However, in the Czech-language milieu in recent years, there have also been descriptions of other forms of so-called “creeping” or “stealth” jihad. The article focused on the analysis of the concepts of “population jihad” or “demographic jihad”, violent “sexual jihad”, “womb jihad” or “wombfare”, and the so-called “great replacement” as presented on websites, radio, and social networks by the authors of the Czech-language anti-Islamic milieu. The present text thus illustrated the use of interpretations of sexual and demographic jihad to rationalize the fear and hatred of Muslims and Islam in the Czech Republic.
Past Continuous or Present Perfect? Continuity and Change in Contemporary Indian Philosophy
Authors: Raveh Daniel
Published: December 2021

Contemporary Indian philosophy is a distinct genre of philosophy that draws both on classical Indian philosophical sources and on Western materials, old and new. It is comparative philosophy without borders. In this paper, I attempt to show how contemporary Indian philosophy works through five instances from five of its protagonists: Krishnachandra Bhattacharyya (his new interpretation of the old rope-snake parable in his essay “Śaṅkara’s Doctrine of Maya”, 1925); Daya Krishna (I focus on the “moral monadism” that the theory of karma in his reading leads to, drawing on his book Discussion and Debate in Indian Philosophy, 2004); Ramchandra Gandhi (his commentary on the concept of Brahmacharya in correspondence with his grandfather, the Mahatma, in his essay “Brahmacharya”, 1981); Mukund Lath (on identity through—not despite—change, with classical Indian music, Rāga music, as his case-study, in his essay “Identity through Necessary Change”, 2003); and Rajendra Swaroop Bhatnagar (on suffering, in his paper “No Suffering if Human Beings Were Not Sensitive”, 2021). My aim is twofold. First, to introduce five contemporary Indian philosophers; and second, to raise the question of newness and philosophy. Is there anything new in philosophy, or is contemporary philosophy just a footnote—à la Whitehead—to the writings of great thinkers of the past? Is contemporary Indian philosophy, my protagonists included, just a series of footnotes to classical thinkers both in India and Europe? Footnotes to the Upaniṣads, Nāgārjuna, Dharmakīrti and Śaṅkara, as much as (let us not forget colonialism and Macaulay) to Plato, Aristotle, Kant and Hegel? Footnotes can be creative and work almost as a parallel text, interpretive, critical, even subversive. However, my contention is that contemporary Indian philosophy (I leave it to others to plea for contemporary Western philosophy) is not a footnote, it is a text with agency of its own, validity of its own, power of its own. It is wholly and thoroughly a text worth reading. In this paper, I make an attempt to substantiate this claim through the philosophical mosaic I offer, in each instance highlighting both the continuity with classical sources and my protagonists’ courageous transgressions and innovations.
Geometrical and Microphysical Properties of Clouds Formed in the Presence of Dust above the Eastern Mediterranean
Authors: Marinou Eleni , Voudouri Kalliopi Artemis , Tsikoudi Ioanna , Drakaki Eleni , Tsekeri Alexandra , Rosoldi Marco , Ene Dragos , Baars Holger , O’Connor Ewan , Amiridis Vassilis , Meleti Charikleia
Published: December 2021

In this work, collocated lidar–radar observations are used to retrieve the vertical profiles of cloud properties above the Eastern Mediterranean. Measurements were performed in the framework of the PRE-TECT experiment during April 2017 at the Greek atmospheric observatory of Finokalia, Crete. Cloud geometrical and microphysical properties at different altitudes were derived using the Cloudnet target classification algorithm. We found that the variable atmospheric conditions that prevailed above the region during April 2017 resulted in complex cloud structures. Mid-level clouds were observed in 38% of the cases, high or convective clouds in 58% of the cases, and low-level clouds in 2% of the cases. From the observations of cloudy profiles, pure ice phase occurred in 94% of the cases, mixed-phase clouds were observed in 27% of the cases, and liquid clouds were observed in 8.7% of the cases, while Drizzle or rain occurred in 12% of the cases. The significant presence of Mixed-Phase Clouds was observed in all the clouds formed at the top of a dust layer, with three times higher abundance than the mean conditions (26% abundance at −15 °C). The low-level clouds were formed in the presence of sea salt and continental particles with ice abundance below 30%. The derived statistics on clouds’ high-resolution vertical distributions and thermodynamic phase can be combined with Cloudnet cloud products and lidar-retrieved aerosol properties to study aerosol-cloud interactions in this understudied region and evaluate microphysics parameterizations in numerical weather prediction and global climate models.
Precise Orbit Determination and Maneuver Assessment for TH-2 Satellites Using Spaceborne GPS and BDS2 Observations
Authors: Zhang Houzhe , Gu Defeng , Ju Bing , Shao Kai , Yi Bin , Duan Xiaojun , Huang Zhiyong
Published: December 2021

The TH-2 satellite system, including the TH-2A and TH-2B, is the first distributed interferometric synthetic aperture radar (InSAR) satellite system in China. During the in-orbit operation, the TH-2A satellite should perform three maneuvers per day to keep the formation flying geometry. We estimate those maneuvers in the precise orbit determination (POD) by the GPS and BDS2 measurements on board, respectively. The residuals of the POD show that the effects caused by orbital maneuvers can be well eliminated for both the GPS and BDS2 data. The precision of the BDS2-based POD is better than 8.0 cm in the three-dimensional direction (3D) compared with the orbit derived from the GPS observations. Such a precision level of the satellite orbit satisfies the InSAR mission requirement of the TH-2. In addition, the relative error of velocity changes is employed to evaluate the maneuver estimations by the POD using the regional navigation system of BDS2. The results show that the relative error of velocity changes between the GPS- and BDS2-based POD is less than 7.0%, which indicates that the maneuver performance extracted from the regional BDS2 data is as good as that extracted from the global GPS data. In the GNSS fused processing, we found that the independent receiver clock offsets should be taken into account, since the time tag corrections for the GPS and BDS2 observations collected on the TH-2 spaceborne receivers were different. The precision of the GPS and BDS2 (GC) combined single point positioning (SPP) can be improved by 12–14% compared with the GPS-only solution when the position dilution of precision (PDOP) of GPS exceeds three. The overlap comparisons of the GC combined orbits show that the internal orbit precision of the TH-2 satellites is better than 0.7 cm. However, the improvement of the GC combined POD result is only 3–4% with respect to the GPS-only solution, which is limited to the precision of the precise orbit and clock products of BDS2 at the present stage.
Single-Image Super-Resolution of Sentinel-2 Low Resolution Bands with Residual Dense Convolutional Neural Networks
Authors: Salgueiro Luis , Marcello Javier , Vilaplana Verónica
Published: December 2021

Sentinel-2 satellites have become one of the main resources for Earth observation images because they are free of charge, have a great spatial coverage and high temporal revisit. Sentinel-2 senses the same location providing different spatial resolutions as well as generating a multi-spectral image with 13 bands of 10, 20, and 60 m/pixel. In this work, we propose a single-image super-resolution model based on convolutional neural networks that enhances the low-resolution bands (20 m and 60 m) to reach the maximal resolution sensed (10 m) at the same time, whereas other approaches provide two independent models for each group of LR bands. Our proposed model, named Sen2-RDSR, is made up of Residual in Residual blocks that produce two final outputs at maximal resolution, one for 20 m/pixel bands and the other for 60 m/pixel bands. The training is done in two stages, first focusing on 20 m bands and then on the 60 m bands. Experimental results using six quality metrics (RMSE, SRE, SAM, PSNR, SSIM, ERGAS) show that our model has superior performance compared to other state-of-the-art approaches, and it is very effective and suitable as a preliminary step for land and coastal applications, as studies involving pixel-based classification for Land-Use-Land-Cover or the generation of vegetation indices.
Land-Surface Quantitative Analysis to Investigate the Spatial Distribution of Gravitational Landforms along Rocky Coasts
Authors: Piacentini Daniela , Troiani Francesco , Torre Davide , Menichetti Marco
Published: December 2021

The increasing availability of high-quality digital elevation models (DEMs) has been associated with a growing interest in developing quantitative analyses aimed at taking advantage of these detailed, updated, and promising digital datasets. Land-surface quantitative (LSQ) analysis is valuable for describing the land-surface topography and performing measures of the signature of specific geomorphic processes, taking into account site-specific geological contexts and morphoclimatic settings, proving to be particularly effective in transitional environments, such as rocky coasts. This paper presents the results of research aimed at investigating the spatial distribution of gravitational landforms along rocky coasts, by means of LSQ analysis based on a DEM with a ground resolution of 2 m, derived from airborne LiDAR (light detection and ranging) surveys. The study area is at Mt. San Bartolo (Northern Marche, Italy) and characterized by a sea cliff diffusely affected by gravitational phenomena of different sizes and types. Geomorphological and geological field data, interpretations of remotely sensed datasets derived from ad hoc unmanned aerial vehicle (UAV) flights, and DEM-derived hillshades were also adapted to support LSQ analysis. In detail, four morphometric variables (slope, roughness, terrain ruggedness index, and elevation standard deviation) were computed and the outputs evaluated based on visual–spatial inspections of derived raster datasets, descriptive statistics, and joint comparison. Results reveal the best performing variables and how combined interpretations can support the identification and mapping of zones characterized by varying spatial distribution of gravitational landforms of different types. The findings achieved along the Mt. San Bartolo rocky coast confirm that an approach based on land-surface quantitative analysis can act as a proxy to efficiently investigate gravitational slope processes in coastal areas, especially those that are difficult to reach with traditional field surveys.
A Human-Following Motion Planning and Control Scheme for Collaborative Robots Based on Human Motion Prediction
Authors: Khawaja Fahad Iqbal , Kanazawa Akira , Kinugawa Jun , Kosuge Kazuhiro
Published: December 2021

Human–Robot Interaction (HRI) for collaborative robots has become an active research topic recently. Collaborative robots assist human workers in their tasks and improve their efficiency. However, the worker should also feel safe and comfortable while interacting with the robot. In this paper, we propose a human-following motion planning and control scheme for a collaborative robot which supplies the necessary parts and tools to a worker in an assembly process in a factory. In our proposed scheme, a 3-D sensing system is employed to measure the skeletal data of the worker. At each sampling time of the sensing system, an optimal delivery position is estimated using the real-time worker data. At the same time, the future positions of the worker are predicted as probabilistic distributions. A Model Predictive Control (MPC)-based trajectory planner is used to calculate a robot trajectory that supplies the required parts and tools to the worker and follows the predicted future positions of the worker. We have installed our proposed scheme in a collaborative robot system with a 2-DOF planar manipulator. Experimental results show that the proposed scheme enables the robot to provide anytime assistance to a worker who is moving around in the workspace while ensuring the safety and comfort of the worker.
Software-Defined NB-IoT Uplink Framework—The Design, Implementation and Use Cases
Authors: Olejniczak Alicja , Błaszkiewicz Olga , Cwalina Krzysztof , Rajchowski Piotr , Sadowski  Jarosław
Published: December 2021

In the radiocommunication area, we may observe a rapid growth of new technology, such as 5G. Moreover, all the newly introduced radio interfaces, e.g., narrowband Internet of Things (NB-IoT), are strongly dependent on the software. Hence, the radiocommunication software development and optimization, as well as the 3GPP technical specification, should be introduced at the academic level of education. In this paper, a software-defined NB-IoT uplink framework in the field of design is presented, as well as its realization and potential use cases. The framework may be used as an academic tool for developing, investigating, and optimizing the digital transmitter paths. The proposed realization is focused on the key elements in the physical layer of the NB-IoT interface used in the sensor devices. Furthermore, the paper also highlights the need of the data processing optimization to minimize the power consumption and usage of the resources of the NB-IoT node during transmitting gathered telemetric data.
Psychometric Study of “Questionnaire of Barriers Perceived” (QBP) in Higher Education
Authors: Hidalgo-Ariza María Dolores , Hinojosa-Pareja Eva Francisca , Muñoz-González Juan Manuel
Published: December 2021

This article presents the process of adaptation and validation, and the resulting psychometric properties, of the “Questionnaire of Barriers Perceived” (QBP). The scale identifies whether a student’s perceptions and expectations are mediated by stereotypes or roles associated with gender through the study of their professional aspirations, fear of negative judgement, and perceptions/awareness of gender roles of men and women. Two descriptive studies were conducted via a cross-sectional poll. The questionnaire was administered first to 240 students and then to a total of 1044 student from all the degrees studied at the Faculty of Education at the university at which the study took place. The data were subjected to item content analysis, descriptive analysis, analysis of internal consistency, study of the relationship between variables, correlational analysis, and an exploratory and confirmatory factorial analysis. The results showed that the scale had a high goodness-of-fit index, as well as validity and reliability. The dimensions that the model comprised were found to be interrelated and coherent with the theoretical structure considered in the initial version of the instrument. The resulting questionnaire presented sufficient validity and reliability to be used in other contexts and studies of the same nature.
Is Digital Government Advancing Sustainable Governance? A Study of OECD/EU Countries
Authors: Durkiewicz Jaromir , Janowski Tomasz
Published: December 2021

International bodies and numerous authors advocate a key role for Digital Government (DG) in improving public governance and achieving other policy outcomes. Today, a particularly relevant outcome is advancing Sustainable Governance (SG), i.e., the capacity to steer and coordinate public action towards sustainable development. This article performs an empirical study of the relationship between DG and SG using data about 41 OECD/EU countries from the United Nations’ E-Government Survey and the Bertelsmann’s Sustainable Governance Indicators project, covering the period from 2014 to 2020. We examine if DG progress pairs with SG progress, apply a DEA model to find out which countries are efficient in using DG for better SG, and uncover cases of imbalance where high DG pairs with poor SG and vice versa. The results show that the efficiency in using DG for SG strongly varies, and that some DG leaders persistently fail to advance or even regress their SG. These findings refute the claims about the benign role of DG and points at democracy as the “weak link” in the analyzed relation.
Sensitivity of Irrigation Water Requirement to Climate Change in Arid and Semi-Arid Regions towards Sustainable Management of Water Resources
Authors: Saeed Fouad H. , Al-Khafaji Mahmoud S. , Al-Faraj Furat A. Mahmood
Published: December 2021

This study aimed to assess the spatiotemporal sensitivity of the net irrigation water requirement (NIWR) to changes in climate, for sixteen crops widely cultivated in four irrigation projects located in arid and semi-arid regions of Iraq. Using LARS-WG and five GCMs, the minimum and maximum temperature and precipitation were projected for three periods from 2021–2080 with 20-year steps (P1, P2, and P3) under representative concentration pathways (RCPs) 2.6, 4.5, and 8.5. Weather data available for a reference period from 1990–2019 in four representatives’ meteorological stations were used. The climate variables and other required data were inserted into the CROPWAT 8 NIWR tool. Findings revealed that the increase in the NIWR for the considered crops due to climate change falls in the range 0.1–42.4%, 1.8–44.5%, 1.2–25.1%, and 0.7–14.7% for the North Jazeera Irrigation Project (NJIP), Kirkuk Irrigation Project (KRIP), Upper Khalis Irrigation Project (UKIP), and Dalmaj Irri-gation Project (DLIP), respectively. Barley is more susceptible to changes in climate, whereas maize, potato, soybean, and millet are found to withstand changes in climate better than others. The novel outcomes of this study support optimal spatiotemporal allocation of irrigation water requirement and the sustainable management of water resources in a changing climate in arid and semi-arid regions.
Overallocation and Correction of Carbon Emissions in the Evaluation of Carbon Footprint
Authors: Gurvich Alex , Creamer Germán G.
Published: December 2021

This paper points to several carbon footprint data distortions that overallocate carbon footprints to individual companies, and to several carbon data intricacies that lead to improved data integrity. Data distortion due to the same company being listed in multiple geographical jurisdictions or through different share classes overstates Emissions Scope 1 by 4.6%, Emissions Scope 2 by 5.5%, Emissions Scope 3 by 10.6% and Reserves by 6.0%. Data distortion due to index construction by having different market capitalization in representative indices overallocates Emissions Scope 1 by 33.9%, Emissions Scope 2 by 27.6%, Emissions Scope 3 by 21.3% and Reserves by 57.2%. A significant amount of carbon data is not precise but is estimated by third-party providers through proprietary techniques. The estimated data for Scope 1 Emissions is 46.4% for the companies in the index. In addition, carbon data is stale, resulting in 94.5% of data being two years old or more. Usage of carbon data in a present format may incorrectly remove some companies from portfolios (negative screen, complete removal) or incorrectly reduce some companies’ weight in a portfolio (partial screen, fractional removal).
A Relationship between Micro-Meteorological and Personal Variables of Outdoor Thermal Comfort: A Case Study in Kitakyushu, Japan
Authors: Hartabela Dadang , Dewancker Bart Julien , Koerniawan Mochamad Donny
Published: December 2021

Outdoor thermal comfort is an important indicator to create a quality and livable environment. This study examines a relationship between micro-meteorological and personal variables of outdoor thermal comfort conditions in an urban park. The data collection of outdoor thermal comfort is carried out using two methods in combination: micro-meteorological measurement and questionnaire survey. This finding shows that most of the respondents were comfortable with the thermal, wind, and humidity condition. The acceptability and satisfaction level of thermal comfort were positive. The most significant micro-meteorological variable for the physiologically equivalent temperature (PET) value is mean radiant temperature (Tmrt). As the Tmrt value is influenced by how much shading is produced from the presence of vegetation or buildings around the measurement location, this finding shows that the shadow was very important to the thermal comfort conditions in the Green Park Kitakyushu. The most influential micro-meteorological variable for the three different personal variables (TSV, WFSV, and HSV) is air temperature. The strongest relationship among the four variables is between TSV and PET. The findings will be the basis for the city authorities in preparing regional development plans, especially those related to the planning of city parks or tourist attractions.
Open Innovation and Competitive Advantage on the Hospitality Sector: The Role of Organizational Strategy
Authors: Musiello-Neto Francisco , Rua Orlando Lima , Arias-Oliva Mario , Silva Amélia Ferreira
Published: December 2021

This paper assesses the relationship between open innovation and competitive advantage and the mediating effect of organizational strategy. Using a quantitative methodological approach with survey data from 251 Portuguese hotel executive directors’ small and medium-sized enterprises (SMEs), this research adopted a quantitative methodological approach, thereby conducting an exploratory and transversal study. Findings show that (1) open innovation influences organizational strategy and (2) organizational strategy enhances competitive advantage. Moreover, the results also highlight that (3) organizational strategy has a mediating effect between open innovation and competitive advantage. The paper provides relevant insights that will lead the firms’ top managers to design and implement strategies and define effective government policies, programs, and incentives to support the development of the firms’ open innovation model in the hospitality sector considering the new smart society and smart cities growing environment.
Psychometric Properties of the Serbian Version of the Operational and Organizational Police Stress Questionnaires
Authors: Kukić Filip , Subošić Dane , Heinrich Katie M. , Greco Gianpiero , Koropanovski Nenad
Published: December 2021

The Police Operational Stress Questionnaire (PSQ-Op) and Police Organizational Stress Questionnaire (PSQ-Org) have been used to assess operational and organizational sources of police officers’ occupational stress. Considering that different cultural and socio-economic environments could affect officers’ perception of operational and organizational stress, country specific psychometric properties and cut-off values should be defined. Therefore, this study aimed to investigate the psychometric properties of the Serbian version of the PSQ-Op and PSQ-Org (i.e., translated in Serbian and adjusted to Serbian culture) and to establish cut-off values for low, moderate and high stress. Methods: The PSQ-Op and PSQ-Org were administered to police officers through the Ministry of Interior of the Republic of Serbia. Participants included 1220 police officers (19.0% female) who correctly completed both questionnaires. Cronbach’s α was used to determine the reliability of instruments. Cut-off values for low, moderate and high stress were defined based on the mean and standard deviation of the sample and using percentile analysis. Prevalence of low, moderate and high stress was calculated according to already established cut-off values as well as those calculated based on the study sample. Results: Both instruments showed high reliability (Cronbach’s α = 0.963 [95% Confidence Interval = 0.957–0.964]). Occupational stress levels (low, moderate and high) were distributed differently (p < 0.001) when categorized according to the cut-off values defined in literature and cut-off values based on the study sample. The cut-off values by mean and standard deviation could be used for PSQ-Op, while cut-off values by percentile analysis could be used for PSQ-Org.
Numerical Investigation on the Dynamic Performance of Steel–Concrete Composite Continuous Rigid Bridges Subjected to Moving Vehicles
Authors: Guo Binqiang , Wang Renzhi , Lu Chen , Shi Weijian , Gao Qingfei
Published: December 2021

Assembly construction is the main feature of industrialized bridges, and π-shaped section steel–concrete composites that are continuously rigid have been widely used in engineering fields in recent years; however, their dynamic responses and corresponding impact coefficients in positive and negative moment regions need to be further studied. First, considering the interface slip model, we established a finite element model for the π-shaped continuous region section of the steel–concrete composite on the Sutai Expressway Tongfu No. 3 viaduct. Second, the bridge deck unevenness parameters were generated by preparing a MATLAB program with random calculations and were added to the bridge deck as the excitation load along with the vehicle load. Such parameters are defined on the basis of considering the vertical degrees of freedom of the four wheels and of one vehicle rigid body. Finally, we analyzed the displacement or stress impact coefficients as the dynamic response index of the bridge by adjusting the vehicle travel speeds, vehicle weights, interface slip stiffness values, and deck unevenness values. The results show that the change in vehicle travel speed and the change in vehicle load weight have some influence on the change in the dynamic effect of the combined beam, but this change is not significant. Moreover, the unevenness and interface slip strength changes have a large effect on the dynamic effect of the combination beam, which can significantly change the impact coefficient of the combination beam bridge. The worse the unevenness of the bridge deck is, the lower the grade of interface slip for the steel–concrete composite bridges and the higher the impact coefficient. We calculated the recommended impact coefficient values of the steel–concrete composite bridge based on the specifications for various countries, and they range from 1.16 to 1.4; such values are similar to the finite element calculation results.
Sustaining Synchronous Interaction Effectiveness in Distance Writing Courses: A Mixed Method Study in a KSA University
Authors: Saeed Murad Abdu , Alharbi Mohammed Abdullah , Yassin Amr Abdullatif
Published: December 2021

The sudden transition to online learning during the COVID-19 pandemic has been challenging for many learners and teachers due to the fact that most universities suddenly shifted to online learning without providing adequate time for preparing and training teachers and learners in using interactive educational technologies. Such challenges are even more pronounced for language instructors in cultivating and sustaining interactions among learners, especially in writing courses that demand active engagement and interactions. Therefore, this study focused on what and how a writing instructor did through technology in creating an interactive writing environment for KSA learners joining five online writing courses and how learners perceived interactions and identifies the major factors affecting their perceptions. The data were collected from multiple sources: WhatsApp chats, Google Docs chats and comments, screencast recorded discussions, students’ texts, and their responses to an electronic (e-) survey as well as follow-up interviews. The study revealed that in connecting Google Docs to the Blackboard Collaborate Ultra, the instructor engaged learners in multidirectional and multimodal interactions and text writing and revising. The WhatsApp group was also used for individual learner-learner and learner-teacher interaction illustrating support and consultation-seeking behaviors of learners beyond the online classroom time. The learners’ perceptions of technology-mediated interactions (overall, learner-learner and learner-teacher) in the online writing courses were at high levels, though such perceptions varied according to several factors, including socio-demographic characteristics. The study concludes by offering useful pedagogical and research implications.
A Note on the w-Pseudo-Orders in Ordered (Semi)Hyperrings
Authors: Qiang Xiaoli , Guan Hao , Rashmanlou Hossein
Published: December 2021

In this work, we study the notion of w-pseudo-order on an ordered (semi)hyperring and give some explicit examples. In addition, we give some examples to compare weak pseudo-order relations with pseudo-order relations. Finally, we construct ordered (semi)hyperrings using regular relations.
Asymmetric Design Sensitivity and Isogeometric Shape Optimization Subject to Deformation-Dependent Loads
Authors: Kim Min-Geun , Koo Bonyong , Han You-Sung , Yoon Minho
Published: December 2021

We present a design sensitivity analysis and isogeometric shape optimization with path-dependent loads belonging to non-conservative loads under the assumption of elastic bodies. Path-dependent loads are sometimes expressed as the follower forces, and these loads have characteristics that depend not only on the design area of the structure but also on the deformation. When such a deformation-dependent load is considered, an asymmetric load stiffness matrix (tangential operator) in the response region appears. In this paper, the load stiffness matrix is derived by linearizing the non-linear non-conservative load, and the geometrical non-linear structure is optimally designed in the total Lagrangian formulation using the isogeometric framework. In particular, since the deformation-dependent load changes according to the change and displacement of the design area, the isogeometric analysis has a significant influence on the accuracy of the sensitivity analysis and optimization results. Through several numerical examples, the applicability and superiority of the isogeometric analysis method were verified in optimizing the shape of the problem subject to deformation-dependent loads.
Research on Segmented Primary Consequent-Pole Permanent Magnet Linear Synchronous Motor with Symmetric and Periodic End Force
Authors: Li Jing , Huang Xuzhen , Zhou Bo , Liu Yansong , Wang Zheng
Published: December 2021

The end force of North-South permanent magnet linear synchronous motor (NS-PMLSM) fluctuates symmetrically with a period of one pole. Different from it, the end force’s fluctuation cycle of the consequent-pole permanent magnet linear synchronous motor (CP-PMLSM) is usually two poles and asymmetrical. Especially, within two half cycles, the end force presents complex asymmetric characteristics. In this paper, a piecewise function model of the end force of CP-PMLSM is established. Then a primary segmented design method for adjusting the period, symmetry and phase of the end force waveform is proposed. The two-segment and grouped four-segment modular distances are combined and matched to eliminate the odd-numbered harmonics of the end force and suppress the thrust ripple. A slotless primary core experimental platform and a slotted CP-PMLSM prototype are manufactured and tested to verify the theoretical analysis and simulation results.
Optimal Conformity Design of Tibial Insert Component Based on ISO Standard Wear Test Using Finite Element Analysis and Surrogate Model
Authors: Takian Wisanupong , Rooppakhun Supakit , Ariyarit Atthaphon , Sucharitpwatskul Sedthawatt
Published: December 2021

Total knee replacement is a standard surgical treatment used to treat osteoarthritis in the knee. The implant is complicated, requiring expensive designs and testing as well as a surgical intervention. This research proposes a technique concerning the optimal conformity design of the symmetric polyethylene tibial insert component for fixed-bearing total knee arthroplasty. The Latin Hypercube Sampling (LHS) design of the experiment was used to create 30 cases of the varied tibial insert conformity that influenced the total knee replacement wear volume. The combination of finite element analysis and a surrogate model was performed to predict wear volume according to the standard of ISO-14243:2014 wear test and to determine the optimal conformity. In the first step, the results could predict wear volume between 5.50 to 72.92 mm3/106 cycle. The Kriging method of a surrogate model has then created the increased design based on the efficient global optimization (EGO) method with improving data 10 design points. The result revealed that the optimum design of tibial insert conformity in a coronal and sagittal plane was 0.70 and 0.59, respectively, with a minimizing wear volume of 3.07 mm3/106 cycle. The verification results revealed that the area surface scrape and wear volume are similar to those predicted by the experiment. The wear behavior on the tibial insert surface was asymmetry of both sides. From this study it can be concluded that the optimal conformity design of the tibial insert component can be by using a finite element and surrogate model combined with the design of conformity to the minimized wear volume.
Hysteretic Behavior on Asymmetrical Composite Joints with Concrete-Filled Steel Tube Columns and Unequal High Steel Beams
Authors: Ji Jing , Zeng Wen , Jiang Liangqin , Bai Wen , Ren Hongguo , Chai Qingru , Zhang Lei , Wang Hongtao , Li Yunhao , He Lingjie
Published: December 2021

In order to acquire the hysteretic behavior of the asymmetrical composite joints with concrete-filled steel tube (CFST) columns and unequal high steel beams, 36 full-scale composite joints were designed, and the CFST hoop coefficient (ξ), axial compression ratio (n0), concrete cube compressive strength (fcuk), steel tube strength (fyk), beam, and column section size were taken as the main control parameters. Based on nonlinear constitutive models of concrete and the double broken-line stress-hardening constitutive model of steel, and by introducing the symmetric contact element and multi-point constraint (MPC), reduced-scale composite joints were simulated by ABAQUS software. By comparing with the test curves, the rationality of the modeling method was verified. The influence of various parameters on the seismic performance of the full-scale asymmetrical composite joints was investigated. The results show that with the increasing of fcuk, the peak load (Pmax) and ductility of the specimens gradually increased. With the increasing of n0, the Pmax of the specimens gradually increases firstly and then gradually decreases after reaching a peak point. The composite joints have good energy dissipation capacity and the characteristic of stiffness degradation. The oblique struts force mechanism in the full-scale asymmetrical composite joint domain is proposed. By introducing influence coefficients (ξ1 and ξ2), the expression of shear bearing capacity of composite joints is obtained by statistical regression, which can provide theoretical support for the seismic design of asymmetrical composite joints.
Manganese-Induced Neurotoxicity through Impairment of Cross-Talk Pathways in Human Neuroblastoma Cell Line SH-SY5Y Differentiated with Retinoic Acid
Authors: Hernández Raúl Bonne , de Souza-Pinto Nadja C. , Kleinjans Jos , van Herwijnen Marcel , Piepers Jolanda , Moteshareie Houman , Burnside Daniel , Golshani Ashkan
Published: December 2021

Manganese (Mn) is an important element; yet acute and/or chronic exposure to this metal has been linked to neurotoxicity and neurodegenerative illnesses such as Parkinson’s disease and others via an unknown mechanism. To better understand it, we exposed a human neuroblastoma cell model (SH-SY5Y) to two Mn chemical species, MnCl2 and Citrate of Mn(II) (0–2000 µM), followed by a cell viability assay, transcriptomics, and bioinformatics. Even though these cells have been chemically and genetically modified, which may limit the significance of our findings, we discovered that by using RA-differentiated cells instead of undifferentiated SH-SY5Y cell line, both chemical species induce a similar toxicity, potentially governed by disruption of protein metabolism, with some differences. The MnCl2 altered amino acid metabolism, which affects RNA metabolism and protein synthesis. Citrate of Mn(II), however, inhibited the E3 ubiquitin ligases–target protein degradation pathway, which can lead to the buildup of damaged/unfolded proteins, consistent with histone modification. Finally, we discovered that Mn(II)-induced cytotoxicity in RA-SH-SY5Y cells shared 84 percent of the pathways involved in neurodegenerative diseases.
Patterns of Diversity of Fusarium Fungi Contaminating Soybean Grains
Authors: Żelechowski Maciej , Molcan Tomasz , Bilska Katarzyna , Myszczyński Kamil , Olszewski Jacek , Karpiesiuk Krzysztof , Wyrębek Joanna , Kulik Tomasz
Published: December 2021

Soybean is an important, high protein source of food and feed. However, like other agricultural grains, soybean may pose a risk to human and animal health due to contamination of the grains with toxigenic Fusaria and associated mycotoxins. In this study, we investigated the diversity of Fusaria on a panel of 104 field isolates obtained from soybean grains during the growing seasons in 2017–2020. The results of species-specific PCR analyses showed that Fusarium avenaceum was the most common (n = 40) species associated with soybean grains in Poland, followed by F. equiseti (n = 22) and F. sporotrichioides (11 isolates). A set of isolates, which was not determined based on PCR analyses, was whole genome sequenced. Multiple sequence analyses using tef-1α, top1, rpb1, rpb2, tub2, pgk, cam and lsu genes showed that most of them belonged to Equiseti clade. Three cryptic species from this clade: F. clavum, F. flagelliforme and FIESC 31 (lacking Latin binomial) were found on soybean for the first time. This is the first report demonstrating the prevalence of Fusaria on soybean grains in Poland.
A Systematic Approach to Consistent Truncations of Supergravity Theories
Authors: Petrini Michela
Published: December 2021

Exceptional generalised geometry is a reformulation of eleven/ten-dimensional supergravity that unifies ordinary diffeomorphisms and gauge transformations of the higher-rank potentials of the theory in an extended notion of diffeormorphisms. These features make exceptional generalised geometry a very powerful tool to study consistent truncations of eleven/ten-dimensional supergravities. In this article, we review how the notion of generalised G-structure allows us to derive consistent truncations to supergravity theories in various dimensions and with different amounts of supersymmetry. We discuss in detail the truncations of eleven-dimensional supergravity to N=4 and N=2 supergravity in five dimensions.
First Evidence of West Nile Virus Overwintering in Mosquitoes in Germany
Authors: Kampen Helge , Tews Birke Andrea , Werner Doreen
Published: December 2021

Mosquitoes collected from mid-December 2020 to early March 2021 from hibernacula in northeastern Germany, a region of West Nile virus (WNV) activity since 2018, were examined for WNV-RNA. Among the 6101 mosquitoes tested in 722 pools of up to 12 specimens, one pool of 10 Culex pipiens complex mosquitoes collected in early March 2021 in the cellar of a medieval castle in Rosslau, federal state of Saxony-Anhalt, tested positive. Subsequent mosquito DNA analysis produced Culex pipiens biotype pipiens. The pool homogenate remaining after nucleic acid extraction failed to grow the virus on Vero and C6/36 cells. Sequencing of the viral NS2B-NS3 coding region, however, demonstrated high homology with virus strains previously collected in Germany, e.g., from humans, birds, and mosquitoes, which have been designated the East German WNV clade. The finding confirms the expectation that WNV can overwinter in mosquitoes in Germany, facilitating an early start to the natural transmission season in the subsequent year. On the other hand, the calculated low infection prevalence of 0.016–0.20%, depending on whether one or twelve of the mosquitoes in the positive pool was/were infected, indicates a slow epidemic progress and mirrors the still-hypoendemic situation in Germany. In any case, local overwintering of the virus in mosquitoes suggests its long-term persistence and an enduring public health issue.
SARS-CoV-2 ORF3a Induces Incomplete Autophagy via the Unfolded Protein Response
Authors: Su Wen-qing , Yu Xue-jie , Zhou Chuan-min
Published: December 2021

In the past year and a half, SARS-CoV-2 has caused 240 million confirmed cases and 5 million deaths worldwide. Autophagy is a conserved process that either promotes or inhibits viral infections. Although coronaviruses are known to utilize the transport of autophagy-dependent vesicles for the viral life cycle, the underlying autophagy-inducing mechanisms remain largely unexplored. Using several autophagy-deficient cell lines and autophagy inhibitors, we demonstrated that SARS-CoV-2 ORF3a was able to induce incomplete autophagy in a FIP200/Beclin-1-dependent manner. Moreover, ORF3a was involved in the induction of the UPR (unfolded protein response), while the IRE1 and ATF6 pathways, but not the PERK pathway, were responsible for mediating the ORF3a-induced autophagy. These results identify the role of the UPR pathway in the ORF3a-induced classical autophagy process, which may provide us with a better understanding of SARS-CoV-2 and suggest new therapeutic modalities in the treatment of COVID-19.
Characterization and Tissue Tropism of Newly Identified Iflavirus and Negeviruses in Glossina morsitans morsitans Tsetse Flies
Authors: Meki Irene K. , Huditz Hannah-Isadora , Strunov Anton , van der Vlugt René A. A. , Kariithi Henry M. , Rezapanah Mohammadreza , Miller Wolfgang J. , Vlak Just M. , van Oers Monique M. , Abd-Alla Adly M. M.
Published: December 2021

Tsetse flies cause major health and economic problems as they transmit trypanosomes causing sleeping sickness in humans (Human African Trypanosomosis, HAT) and nagana in animals (African Animal Trypanosomosis, AAT). A solution to control the spread of these flies and their associated diseases is the implementation of the Sterile Insect Technique (SIT). For successful application of SIT, it is important to establish and maintain healthy insect colonies and produce flies with competitive fitness. However, mass production of tsetse is threatened by covert virus infections, such as the Glossina pallidipes salivary gland hypertrophy virus (GpSGHV). This virus infection can switch from a covert asymptomatic to an overt symptomatic state and cause the collapse of an entire fly colony. Although the effects of GpSGHV infections can be mitigated, the presence of other covert viruses threaten tsetse mass production. Here we demonstrated the presence of two single-stranded RNA viruses isolated from Glossina morsitans morsitans originating from a colony at the Seibersdorf rearing facility. The genome organization and the phylogenetic analysis based on the RNA-dependent RNA polymerase (RdRp) revealed that the two viruses belong to the genera Iflavirus and Negevirus, respectively. The names proposed for the two viruses are Glossina morsitans morsitans iflavirus (GmmIV) and Glossina morsitans morsitans negevirus (GmmNegeV). The GmmIV genome is 9685 nucleotides long with a poly(A) tail and encodes a single polyprotein processed into structural and non-structural viral proteins. The GmmNegeV genome consists of 8140 nucleotides and contains two major overlapping open reading frames (ORF1 and ORF2). ORF1 encodes the largest protein which includes a methyltransferase domain, a ribosomal RNA methyltransferase domain, a helicase domain and a RdRp domain. In this study, a selective RT-qPCR assay to detect the presence of the negative RNA strand for both GmmIV and GmmNegeV viruses proved that both viruses replicate in G. m. morsitans. We analyzed the tissue tropism of these viruses in G. m. morsitans by RNA-FISH to decipher their mode of transmission. Our results demonstrate that both viruses can be found not only in the host’s brain and fat bodies but also in their reproductive organs, and in milk and salivary glands. These findings suggest a potential horizontal viral transmission during feeding and/or a vertically viral transmission from parent to offspring. Although the impact of GmmIV and GmmNegeV in tsetse rearing facilities is still unknown, none of the currently infected tsetse species show any signs of disease from these viruses.
Prior Methamphetamine Use Disorder History Does Not Impair Interoceptive Processing of Soft Touch in HIV Infection
Authors: Bischoff-Grethe Amanda , Ellis Ronald J. , Tapert Susan F. , Paulus Martin P. , Grant Igor ,   Translational Methamphetamine AIDS Research Center (TMARC)
Published: December 2021

Introduction: Interoception, defined as the sense of the internal state of one’s body, helps motivate goal-directed behavior. Prior work has shown that methamphetamine (METH) use disorder is associated with altered interoception, and that this may contribute to risky behavior. As people with HIV (PWH) may also experience disrupted bodily sensations (e.g., neuropathy), an important question is whether PWH with a history of METH use disorder might exhibit greater impairment of interoceptive processing. Methods: Eighty-three participants stratified by HIV infection and a past history of methamphetamine use disorder experienced a soft touch paradigm that included slow brush strokes on the left forearm and palm during blood-oxygen level-dependent functional MRI acquisition. To assess differences in interoception and reward, voxelwise analyses were constrained to the insula, a hub for the evaluation of interoceptive cues, and the striatum, which is engaged in reward processing. Results: Overall, individuals with a history of METH use disorder had an attenuated neural response to pleasant touch in both the insula and striatum. Longer abstinence was associated with greater neural response to touch in the insula, suggesting some improvement in responsivity. However, only PWH with no METH use disorder history had lower brain activation in the insula relative to non-using seronegative controls. Conclusions: Our findings suggest that while METH use disorder history and HIV infection independently disrupt the neural processes associated with interoception, PWH with METH use disorder histories do not show significant differences relative to non-using seronegative controls. These findings suggest that the effects of HIV infection and past methamphetamine use might not be additive with respect to interoceptive processing impairment.