bluuebunny/crossref_metadata_2025 huggingface dataset:
Dímero-D como factor predictor de eventos trombóticos en pacientes con infección por SARS-Cov-2 atendidos en la clínica Unión, Guayaquil
Authors: Macias Puertas María Fernanda , Baque Pin Jonathan Andrés , Mendoza Sancan Fabricio Jahir , Jaime Mora Vicente Augusto
Published: December 2024

La infección por SARS-CoV-2 se ha asociado con un mayor riesgo de eventos trombóticos, que pueden resultar en complicaciones graves. El dímero-D por su parte es un fragmento de proteína que se libera en la sangre cuando se forma un coagulo. Estudios recientes sugieren que las muertes por SARS-CoV-2 suelen estar vinculadas a la presencia de coagulopatías, y que un valor de dímero-D, superior a 1 µg/ml, se asocia con un aumento en la mortalidad. Por lo tanto, el presente estudio tuvo por objetivo determinar el Dímero-D como factor predictivo de eventos trombóticos en pacientes con infección por SARS-CoV-2 en la clínica unión, ciudad de Guayaquil. Para el cual se utilizó una metodología con un enfoque cuantitativo, descriptivo, de tipo observacional retrospectivo, incluyó 298 pacientes atendidos en la Clínica Unión en un tiempo establecido, de los cuales el 49,3% presentó la infección. En este grupo, el 45,3% manifestó valores elevados de dímero-D. Además, se registraron 89 casos de eventos trombóticos, siendo la trombosis venosa profunda la más frecuente, con 37 casos. En la población no infectada, se documentó un solo caso de dímero-d elevado. Finalmente se concluyó que existe un riesgo aumentado de presentar algún tipo de trombosis, cuando se tiene antecedentes de infección por Sars-CoV-2 y los valores de dímero-D se encuentra sobre el límite de lo normal, es decir a mayor concentración de este biomarcador en la sangre, mayor predisposición a desarrollar un evento trombótico.
Scheduling Theory Problem with an Unfixed Start Time
Authors:   The University of Georgia, Kutkhashvili Ketevan , Kilasonia Neli ,   GTU Institute of Control Systems
Published: December 2024

The paper discusses the problem when the achievement of the optimal goal depends on the sequence of tasks, i.e., when it is necessary to arrange them in time. Such problems are known to belong to calendar scheduling problems and are in general of NP complexity. It is possible to build a polynomial algorithm only in the case of a certain configuration of the initial parameters. In the paper, one such configuration is considered and financial cost minimization is taken as a criterion for achieving the goal.
Algorithm for Extraction Common Properties of Objects Described in the Predicate Calculus Language with Several Predicate Symbols
Authors:   St Petersburg University, Kosovskaya Tatiana , Zhou Juan ,   St Petersburg University
Published: December 2024

When solving artificial intelligence problems connected with the study of complex structured objects, a convenient tool for describing such objects is the language of predicate calculus. The paper presents two algorithms for the extraction of common properties of objects described in the predicate calculus language with predicate symbols. The first of the algorithms extracts maximal common subformulas for elementary conjunctions containing 2 predicate symbols. The second algorithm extracts maximal common subformulas for elementary conjunctions with several predicate symbols. Estimates of their time complexity are given for both algorithms. Both algorithms are implemented in Python.
Manipulative Maneuvers: A Comparative Study of Othello and King Lear
Authors: Gul Sania , Nauman Muhammad , Gul Maira
Published: December 2024

William Shakespeare is famous for the universality and uniqueness of his plays. Most of the characters that he portrays are life-like. In most of his plays, he describes some manipulative characters who cunningly ruin the lives of those around them. People trust, love, and admire them, but in response, these manipulative persons exploit them to achieve their goals. Othello (1603) and King Lear (1605) are two different tragic plays written by Shakespeare, and both have manipulative characters, i.e., Iago in Othello and Edmond in King Lear. They have been analyzed in this study to discover Shakespeare's understanding of human nature as manipulative in society and the meaningful similarities between them in light of the comparative contextual analysis technique. The findings reveal Shakespeare's nuanced portrayal of manipulative characters, showcasing the parallel yet distinct paths taken by Iago in "Othello" and Edmund in "King Lear," highlighting their cunning tactics, societal impact, and the universal thread of human manipulation; the conclusion underscores Shakespeare's profound comprehension of the darker facets of human nature, depicting the intricate interplay of manipulation, trust, and societal influence within his tragic plays.
Liquefied Petroleum Gas (LPG) Tanker Cargo and Ballast Handling Simulator
Authors:   International Maritime Organization
Published: December 2024

This course aims to meet the mandatory standards of competence in advanced training for liquefied gas tanker cargo operations, particularly for LPG tanker cargo and ballast operations using approved simulator training. Tailored to the trainees’ needs and experience levels, the course is a key resource to aid trainees in mastering essential procedures and equipment in compliance with international standards.
RELEVANSI HADITS NABI DALAM MENANGGAPI TANTANGAN ETIKA MEDIA SOSIAL DI ERA DIGITAL
Authors: Trisna Dwi Nur Rodhiyah  , Nasrulloh Nasrulloh
Published: December 2024

Dalam era digital di zaman sekarang, media sosial telah menjadi alat utama yang terpenting untuk berbagi informasi dan berinteraksi dengan masyarakat. Namun, di sisi lain, globalisasi juga membawa tawaran yang menggoda berupa kebebasan tanpa batas, individualisme, pragmatisme, budaya instan, hedonisme, konsumerisme, serta budaya kapitalisme yang bersifat global, sehingga nilai-nilai kearifan tradisional yang bersifat lokal seolah tercampur menjadi satu. Penelitian ini menggunakan metode analisis kualitatif berbasis teks hadits dan relevansi kontemporer. Penelitian ini bertujuan untuk membahas hadits Nabi dalam etika dalam bermedia sosial. Hadits Nabi memberikan panduan universal dalam menjaga etika di media sosial. Prinsip-prinsip ini relevan untuk mengatasi tantangan digital di era modern. Hasil penelitian menunjukkan bahwa prinsip-prinsip etika dalam hadits Nabi, seperti amar ma’ruf nahi munkar, tabayyun (klarifikasi), dan menjaga kehormatan orang lain, memiliki relevansi yang kuat dalam menghadapi tantangan etika di era digital. Implementasi nilai-nilai ini diharapkan dapat membentuk perilaku bermedia sosial yang lebih sehat, bertanggung jawab, dan sesuai dengan tuntunan Islam.
Model of Causal Factors of Network Management Capabilities Affecting Market Opportunity and Performance of Community Enterprises
Authors: Lalaeng Chanyaphak , Sumpathanon Chanita , Boonnual Chutimant
Published: December 2024

Objectives: Research Model of causal factors of network management capabilities affecting market opportunity and performance of community enterprises. This paper examines to check the consistency of the model. To develop a model of causal factors of network management capabilities affecting market opportunity and performance of community enterprises in this sector. Methods: The population used in this study was a group of small and medium-sized enterprises in the upper southern region of Thailand, a sample of 320 (Wiratchai, 1999). Using the PLS model, a two-stage approach was used for direct path and mediation effect analysis with high-dimensional latent variables. Results: The analysis revealed that both PCBE and CL were statistically significant in relation to NMC. Furthermore, NMC were found to be statistically significant for Market opportunity (MO) and Business performance (BP). However, MO did directly influence BP. Conclusions: In light of these findings, we discuss the theoretical and practical implications, limitations of the study. This study underscores the importance of Perceived changes in the business environment and Creative leadership the indirect pathways through which Network management capabilities contribute to Market opportunity success and Business performance.
化学分析实验室检测数据准确性的控制策略
Authors: 孙慧
Published: December 2024

孙慧
南京化学试剂股份有限公司，南京市，江苏省，中国
摘要：化学分析实验室的检测数据在科研、生产和环境监测中具有广泛应用，其准确性直接影响到科研成果的可信度、产品质量控制和环境风险评估。由于化学分析过程涉及多种复杂因素，包括仪器设备的性能、操作人员的技能以及实验环境的稳定性，因此，如何有效控制检测数据的精度成为实验室管理的重要任务。本文探讨了通过人员培训、设备校准、质量管理体系、实验设计和环境控制等多方面的综合策略，提高化学分析实验室检测数据准确性的方法，并提出了有效的审查流程和验证手段，以确保实验结果的可靠性。
生物检测试剂保藏技术研究
Authors: 秦晖
Published: December 2024

秦晖
南京化学试剂股份有限公司，南京市，江苏省，中国
摘要：生物检测试剂的活性和稳定性直接影响检测结果的准确性。为了在常温条件下实现长时间保存和非冷链运输，采用了多种保藏技术，包括低温保藏、真空冷冻干燥、喷雾干燥和玻璃化冷冻。通过对这些技术的研究，发现不同技术在保持试剂生物活性和延长保存期限方面各具特色。本文深入分析了各技术的工作原理和具体应用措施，并探讨了冷却速率、添加保护剂、包装等对试剂活性的影响。
EL FEDERALISMO FISCAL MEXICANO: UN ESTUDIO COMPARADO ENTRE LOS ESTADOS DE MÉXICO, GUANAJUATO Y TABASCO
Authors: HERNÁNDEZ SALIN JOSÉ ANTONIO
Published: December 2024

entre los estados de México, Guanajuato y Tabasco” tiene por objetivo general analizar los mecanismos por los cuales el cambio institucional permite reacomodos en el alineamiento partidista, observados como realineamientos o desalineamientos entre el gobierno nacional y los de las entidades federativas de Guanajuato, Estado de México y Tabasco, en el periodo comprendido entre el año 2000 y 2018 permitiendo mecanismos normativos e institucionalizados tendientes a la centralización y discrecionalidad en la asignación y distribución de recursos fiscales contenidos en los Ramos 28 y 33, por lo que se hace uso del método comparativo para contrastar las unidades de análisis referente a las dos variables de interés: cambio institucional y federalismo fiscal.
Identidades em contexto: percepções dos alunos ouvintes sobre sinalizantes de Libras em sala de aula
Authors: Araújo Mariana Costa , Pereira Antonio Renaldo Gomes
Published: December 2024

A inclusão de alunos com deficiência auditiva em escolas regulares é desafiadora, contudo, essencial para promover um ambiente educacional mais inclusivo. A presença de intérpretes de Libras é fundamental, garantindo comunicação e participação efetiva dos alunos surdos. A Escola de Ensino Fundamental Maria do Socorro Gouveia, situada em São Gonçalo do Amarante, Ceará, possui quatro alunos com deficiência auditiva, mas apenas um é assistido por um intérprete. Assim, esse estudo tem por objetivo apresentar uma descrição reflexiva sobre interação de alunos ouvintes com sua colega surda e a intérprete de Libras em uma turma do oitavo ano. Observe-se que a inclusão vai além da presença física, exigindo mudanças nas práticas pedagógicas e atitudes. Embora haja interesse dos alunos em aprender Libras, ainda há barreiras na comunicação direta com a aluna surda, destacando a necessidade de mais ações incluídas.
Advancing Swine Management in Buenavista, Guimaras: Foundations for Effective Extension Program
Authors: Vergara Julius
Published: December 2024

This research paper was created to assess the management practices of swine raisers in Buenavista, Guimaras. The health of livestock and the economic sustainability of the farming sector in Guimaras, Philippines, are contingent upon the management and disease prevention strategies employed in pig farming. This study employed a descriptive design utilizing quantitative methods to analyze data through frequency counts and percentages, assessing swine management techniques among fifty swine raisers in Buenavista, Guimaras. The sample comprised fifty swine producers, predominantly aged between 46 and 58. Women represented 54% of the respondents, with 60% indicating that their spouses predominantly managed pig farming activities. Moreover, 58% of interviewees indicated they lacked primary authority within their households. Seventy-four percent of participants commenced pig farming between 2012 and 2022, with the majority (ninety-two percent) possessing between one and forty pigs. Seventy-seven percent of farms provide triennial feeding for pigs, indicating a general consistency in feeding practices. Ninety-six percent of all option groups indicated a preference for grower feed and a rejection of swill feeding. Although they adhered to the standards for normal feeding, their sanitation practices were inconsistent; merely 52% reported cleaning pigpens thrice daily, and only 24% utilized disinfectants. A similar trend in recordkeeping was noted: just 64% of pig producers kept a journal of their operations. 84% of respondents indicated their swine efforts were adjacent to a pig-rearing farm.
An Onto-Axiological Argument for the Existence of God
Authors: Bertato Fábio
Published: December 2024

The article presents an Onto-Axiological Argument for the existence of God, formalized in first-order logic. It combines ontological and axiological principles, arguing that God is superior to all other entities in all relevant aspects, including the aspect of being. The existence of contingent entities is an a posteriori premise of the argument, which culminates in a formal demonstration of God’s existence in act. The consistency of the underlying theory is demonstrated through a very simple model, and its interpretation is succinctly discussed in relation to Aristotelian-Thomistic metaphysics, although it is applicable to other philosophical contexts. The argument seeks logical rigor and conceptual clarity, offering a novel contribution to debates on the existence of God.
RASTREADOR OCULAR COMO FERRAMENTA DE AVALIAÇÃO DA APRENDIZAGEM EM ALUNOS COM AUTISMO: UMA REVISÃO INTEGRATIVA
Authors: De Souza Sauaia Vansiler Nair Daiane , Venturieri Bianca
Published: December 2024

As dificuldades em avaliar a aprendizagem de crianças com Transtorno do Espectro Autista (TEA) têm sido um tema central de pesquisa no Brasil. O uso do rastreamento ocular, por não ser invasivo e não exigir respostas motoras complexas ou linguagem escrita, tem se mostrado particularmente relevante para o estudo de indivíduos com TEA. Este artigo apresenta os resultados de uma revisão integrativa sobre a aplicação do rastreador ocular como ferramenta de avaliação da aprendizagem de alunos com TEA. A metodologia utilizada consistiu em uma revisão bibliográfica de estudos realizados no Brasil sobre a avaliação da aprendizagem de crianças com TEA em idade escolar, da educação infantil até o final do ensino fundamental I, utilizando o rastreador ocular. Os resultados indicam que os participantes apresentam maior tempo de fixação em objetos familiares e coloridos, além de dificuldades em tarefas que envolvem organização frasal. Concluímos que o rastreamento ocular é uma ferramenta eficaz para avaliar a aprendizagem de crianças com TEA, oferecendo dados valiosos para a personalização de atividades de ensino, conforme as características individuais de cada aluno autista.
REDECA Framework Enhancing Occupational Safety and Health Through Artificial Intelligence Applications
Authors: Michiel Sheila , Moissact Isabelle , Sean Christopher
Published: December 2024

Objective: This paper aims to show how REDECA Reengineering Delphi and Evaluation can be integrated with Artificial Intelligence (AI) in a way to increase the influence of AI on Occupational Safety and Health (OSH) by further advancing the risk identification process, the prevention of injuries, and the compliance with safety standards.Methods: A quantitative cross-sectional study method was used through multiple regressions analysis for the relationships between AI application, risk identification, injury reduction, safety culture, and compliance. Organizational safety culture was explored further as a moderator influencing the effectiveness of AI in OSH systems.Results: AI enhances the identification and prediction of risk, resulting in a significant reduction in workplace injuries and fatalities. AI-enabled applications ensure higher adherence to safety protocols and helped in building a time-tested safety culture. In fact, organizational safety culture improves the effectiveness of AI, serving as a vital moderating factor that facilitates lasting advancements in workplace safety practices. This points to the relationship between technological innovation and organizational influences on better OSH outcomes.Novelty: This study presents an original integration of AI-driven predictive safety mechanisms through the REDECA framework, highlighting the moderating role of safety culture. This serves as a bridge between technology adoption and organizational behavior to advance workplace safety strategies.Research Implication: The findings provide a roadmap to organizations to not just invest in AI-based safety systems but also to inculcate a strong safety culture to reap the rewards of technical advances. This research sends a message to the fostering of the AI integration as a transformative approach for OSH management, which aims for the sustainable improvements in workplace safety, risk mitigation and employed well-being for the policymakers and the industry leaders.
El Método Jigsaw para la enseñanza del inglés en CEUTEC de San Pedro Sula
Authors: Guillén Mancía Jenny Elizabeth
Published: December 2024

Introducción. El método Jigsaw, también conocido como rompecabezas (traducido al español), permite el desarrollo del trabajo cooperativo dentro del aula, favoreciendo la interdependencia positiva, la interacción, la fluidez comunicativa, la sociabilidad, el respeto y el aprendizaje activo y significativo. Método. Se llevó a cabo el uso del método Jigsaw en la clase de inglés con un grupo de 23 estudiantes para aprender y fortalecer el uso del verbo en el tiempo presente simple (The Present Simple). De esta manera, los estudiantes fueron capaces de desarrollar oraciones afirmativas, negativas, preguntas puntuales y preguntas de contenido. Los alumnos se agruparon en equipos de cuatro, excepto uno. El método Jigsaw requiere que los equipos de trabajo consten de cantidades iguales, pero existe un método que resuelve este caso conocido como Jigsaw II. A cada alumno se le delegó un tema para desarrollarlo. Resultados. Los alumnos integran un nuevo grupo llamado el grupo experto que consiste en reunir los alumnos con el mismo tema de estudio para que compartan su hallazgo y la resolución. De esta manera se convierten en expertos del tema. Por último, cada integrante del grupo experto se remitió a su grupo Jigsaw para compartir con los miembros de su equipo el conocimiento adquirido durante su aprendizaje. Conclusión. La actividad resultó efectiva, ya que cada alumno fue capaz de aprender The Present Simple y utilizarlo de forma correcta.
Conociendo a los Estudiantes a través del Lente de la Cámara de su Teléfono
Authors: Moya Mantilla Ana María
Published: December 2024

Introducción. Entre los desafíos de un docente está el hecho conocer a sus estudiantes. En ese sentido, el ensayo fotográfico es una de las mejores formas de lograrlo, ya que consiste en un autorretrato de cómo ellos se perciben o cómo quieren que los demás los vean. Método. Debido a que la mayoría de los estudiantes no cuenta con una cámara DSRL, fue reto es realizar la actividad con su cámara del teléfono. Resultados. Lo anterior resaltó la capacidad del fotógrafo para contar una historia. Asimismo, se logró una mayor conexión entre los compañeros y se conoció la personalidad de cada uno. Discusión. En el proceso de evaluación, se les solicitó a los alumnos que exploraran una idea relacionada con su entorno y estudiaran referentes para luego fotografiarlos. Conclusión. La experiencia concluyó con una socialización con el resto de la clase; de esta manera, se identificaron las ideas implícitas, el concepto y el proceso. La actividad permitió conocer los intereses y personalidades de los estudiantes.
Intervención Educativa Remedial con Niños de Escasos Recursos Económicos en el Ecuador
Authors: Stuecher Uwe H. , Hjelle Ryan J. , Cabeza Stuecher Marizela R. , Foronda Rojo Ainize
Published: December 2024

La investigación de los últimos años ha mostrado una aparente conexión entre pobreza y problemas de aprendizaje que afecta la vida futura de los niños. Mientras que en Estados Unidos se han implementado programas escolares de intervención temprana (Head Start Program) para afrontar esta problemática, la investigación internacional en torno a programas sostenibles en este campo es escasa. El presente artículo describe una intervención educativa sostenible implementada en diferentes áreas empobrecidas de las tierras altas andinas y zonas costeras de Esmeraldas, Ecuador. Este programa piloto se desarrolló durante dos años en 19 escuelas rurales económicamente desfavorecidas (N = 400 estudiantes). El alumnado evaluado en el cuartil más bajo de su grupo de pares en cuanto a su desempeño académico participó en un programa extraescolar que incluía una merienda nutritiva y atención médica cuando fuera necesario. A los seis meses de intervención la prueba t de Student para comparar medias mostró una mejoría significativa en las puntuaciones pre-post del alumnado participante en el programa de intervención, con tamaños de efecto elevados.Palabras clave: Ecuador; programa remedial; grupo desfavorecido; dificultades de aprendizaje; educacion primaria.  AbstractResearch during the last years has indicated an apparent connection between poverty and learning problems, which affect the children’s life in the future. While programs such as Head Start have been implemented in the United States to ally this problem, international research into sustainable programs is scarce. This paper details a sustainable multi-site education intervention that was implemented in impoverished areas of the Andean highlands and coastal areas of Esmeraldas, Ecuador. This pilot program was conducted over a two-year period at 19 rural/economically-deprived schools (N=400 students). Those students who tested in the lowest quartile of their peer group for academic functioning were provided with an afterschool program, which included a nutritious snack, and medical attention as needed. At the conclusion of this six-month intervention, paired-sample t-tests indicated significant improvement on pre-post test scores, with large effect sizes, for those children in the lowest quartile of their class.Keywords: Ecuador; remedial program; disadvantaged; learning difficulties; primary education.
Formación de Gestores Ambientales Comunitarios para Mitigar la Contaminación de la Microcuenca Jipiro
Authors: Gonzaga Figueroa Aurita G.
Published: December 2024

La solución a la problemática ambiental enfocada a eliminar la contaminación de las microcuencas solo es posible resolverla de manera sostenible, es decir cuando los cambios que se proponen para mitigar los impactos ambientales de la contaminación de las aguas se centran en la conciencia del hombre, ya que vive y actúa en esa realidad interactuando mediante sus actitudes y conductas, muchas veces inconscientes. El presente artículo tiene el propósito de reflexionar sobre una experiencia de educación ambiental comunitaria dirigida a la formación de gestores ambientales comunitarios para el fomento de la conciencia crítica de la población para mitigar la contaminación en la Microcuenca Jipiro, Loja.
En la investigación se aplica una metodología para el autodesarrollo comunitario (MAC), que por su esencia participativa, desarrolladora y emancipadora logra en la ciudadanía el desarrollo de la conciencia crítica y el fomento de una cultura ambiental de la población en estudio. En la misma se aplican diversos métodos de investigación como la observación participante, encuestas, entrevistas, análisis de documentos y se aplican numerosos dispositivos grupales.
Las transformaciones logradas a nivel individual y grupal en el grupo de gestores ambientales en formación mostraron un mayor nivel de desarrollo de la conciencia crítica y la apropiación de un sistema de conocimientos, habilidades, actitudes y valores reflejo de una cultura ambiental formada.
Los Métodos de Enseñanza del Inglés en la Preparación Idiomática Requerida por la Universidad del Siglo XXI
Authors: Ramírez Lozada Haydeé , Perlaza Rodríguez Marjorie K. , Sosa Daza Erick P. , Bautista Salazar Fiama S.
Published: December 2024

La preparación idiomática en inglés es un imperativo para la Universidad del Siglo XXI. Con el propósito de analizar los métodos de enseñanza que se utilizan para el proceso de enseñanza-aprendizaje del inglés general en estudiantes del primer nivel de inglés, en la PUCE Sede Esmeraldas, se desarrolló una investigación cuanti-cualitativa con los métodos analítico-sintético, hermenéutico-dialéctico y estadístico, las técnicas de la observación y la encuesta, a una población de 110 estudiantes y 4 docentes de inglés general de los primeros niveles de diferentes carreras en la institución mencionada. Los resultados revelaron que los docentes utilizan una variedad de métodos en el aula que incluye el Enfoque Basado en Tareas (EBT), el Método Directo, el de Gramática-Traducción, el Audio-Lingual, el de Respuesta Física Total, el Aprendizaje Comunitario y el Enfoque Comunicativo, con el uso de la Metodología Lúdica en algunas ocasiones. Los docentes preparan actividades dinámicas para activar el aprendizaje y los estudiantes están involucrados en el aprendizaje, interactuando en parejas y grupos. Los estudiantes indicaron que les gustaría aprender con el uso de canciones, juegos, videos y el drama, en actividades comunicativas. Estos resultados permitieron concluir que en la didáctica del inglés general se utiliza un eclecticismo metodológico que permite desarrollar el inglés en estudiantes de diferentes especialidades e intereses.
Desarrollo Sostenible: Un Estudio Desde la Perspectiva del Derecho Internacional y la Legislación Ecuatoriana
Authors: Figuera Vargas Sorily C. , Cordero Silva Cristian A.
Published: December 2024

Este ensayo se enfoca en el estudio del desarrollo sostenible desde una visión jurídica. Disertamos sobre qué es realmente el desarrollo sostenible, sobre cuál fue su origen y cómo ha sido tanto su evolución como estructuración desde el ámbito normativo internacional. Igualmente, se examinó cómo el sistema legal ecuatoriano adoptó este concepto en la Constitución de 2008 y en sus diversos cuerpos legislativos internos. El objetivo de esta reflexión fue analizar si resulta eficaz la regulación internacional y nacional sobre el desarrollo sostenible, teniendo como parámetro al Estado ecuatoriano. Mediante un método de investigación jurídico - descriptivo, se estudiaron las regulaciones emblemáticas del desarrollo sostenible y cuáles serían sus aplicaciones prácticas. Al estar frente al reto de la Agenda 2030 para el Desarrollo Sostenible de las Naciones Unidas, donde se tienen diecisiete objetivos (ODS) por delante, en este ensayo se planteó qué tan ambiciosos resultan los mismos y se concluyó como Ecuador tiene las herramientas jurídicas para lograrlos, quedando la incógnita si existirá la voluntad para alcanzarlos.
Editorial
Authors: Hallazgo21 Editorial
Published: December 2024

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The Analysis Study of Association of Cigarette Smoking and Dry Eye Disease : A Comprehensive Systematic Review
Authors: Anindi Putri Harjanti  , Indrawati
Published: December 2024

Background: Dry eye disease prevalence is significantly influenced by smoking, with cigarette smoke contributing to over seven million deaths annually. Despite the widespread use of electronic cigarettes, public awareness remains limited, and debates persist regarding their safety and long-term health implications, highlighting the urgent need for improved health measures. Methods: This systematic review complied with the PRISMA 2020 requirements, concentrating solely on full-text papers published in English from 2014 to 2024. Editorials and review articles lacking a DOI were omitted to guarantee the use of high-quality sources. A comprehensive literature review was performed using esteemed databases such as ScienceDirect, PubMed, and SagePub to locate pertinent studies. Result: An initial database search identified more than 60 publications relevant to the topic. Following a meticulous three-stage screening process, eight studies were ultimately selected based on predefined inclusion criteria and deemed appropriate for in-depth analysis. These studies underwent a thorough critical appraisal to ensure their quality and relevance, providing a solid foundation for a comprehensive investigation into the association between cigarette smoking and dry eye disease. Conclusion: DED, a common ophthalmology condition, is often underdiagnosed due to its nonspecific symptoms and variability in diagnostic approaches. Cigarette smoke causes lipid peroxidation, tear film instability, and ocular surface damage, impairing epithelial differentiation.
Zakonska regulativa obavljanja studentskih poslova putem posrednika
Authors: Tolušić Edita , Bedeković Mladena , Vakanjac Danijela
Published: December 2024

Rad studenata u Republici Hrvatskoj reguliran je Zakonom o obavljanju studentskih poslova kojim se uređuju prava i obveze izvođača, posrednika i naručitelja posla tijekom obavljanja studentskog posla kao i ostala pitanja vezana uz obavljanje studentskih poslova. Stoga je svrha rada istražiti zakonski okvir obavljanja studentskih poslova jer studentske poslove, osim studenata, mogu obavljati i druge osobe, a ti poslovi mogu se obavljati jedino putem posrednika koji mogu biti studentski centri ili visoka učilišta koja imaju centar za studentski standard kao ustrojstvenu jedinicu. Također, ono mora imati odobrenje djelatnosti posredovanja izdano od strane Ministarstva znanosti i obrazovanja. Cilj je rada, pored definiranja osoba koje mogu obavljati studentske poslove, prikazati i ulogu posrednika, kao i sam sadržaj studentskog ugovora te porezni tretman studentskog rada budući da se studentski poslovi obavljaju temeljem studentskog ugovora koji je vjerodostojna isprava za obračun i naplatu naknade za obavljanje poslova i doprinosa. Metodologija istraživanja obuhvaća analizu relevantnih sekundarnih podataka te analitički pristup obračunavanju studentskih poslova pod različitim uvjetima. Dobiveni rezultati istraživanja su pokazali do kojih bitnijih pomaka je došlo nakon izmjena zakonskih odredbi te kakva je porezna perspektiva obavljanja studentskih poslova tijekom studiranja, jer takvi poslovi studentima omogućavaju stjecanje radnog iskustva, a nije zanemariv ni iznos ostvarenog primitka koji im omogućava poboljšanje studentskog standarda.
Od oskudice radne snage do oskudice poslova
Authors: Jemrić Ostojić Ines , Jurina Babović Natalija , Kelava Marin
Published: December 2024

Svrha ovog istraživanja je ispitati učinke digitalne transformacije na trenutno tržište rada i na budućnost rada. Istraživanje ima za cilj analizirati transformativnu ulogu tehnologija poput umjetne inteligencije (AI), Interneta stvari (IoT) i velikih podataka (Big data), te razmotriti implikacije triju ključnih teorijskih perspektiva: teoriju oskudice radne snage, teoriju kraja rada i teoriju oskudice poslova. Metodologija istraživanja uključuje sveobuhvatan pregled literature i podataka. Korišteni su i kvalitativni i kvantitativni podaci kako bi se procijenio utjecaj tehnoloških inovacija na obrasce zapošljavanja, zahtjeve za vještinama i na ekonomske strukture. Članak također uključuje teorijski okvir za istraživanje promjenjivog odnosa između tehnologije, obrazovanja i budućnosti rada. Rezultati pokazuju da tehnološke inovacije Četvrte industrijske revolucije preoblikuju tržište rada automatizirajući rutinske zadatke, stvarajući nove kategorije poslova i povećavajući potražnju za digitalnom pismenošću i specijaliziranim vještinama. Teorija oskudice radne snage sugerira stalnu potražnju za visoko kvalificiranom radnom snagom, odražavajući potrebu za naprednim vještinama i poboljšanim sposobnostima na evoluirajućem tržištu rada. S druge strane, teorija kraja rada predviđa značajno smanjenje zaposlenja zbog automatizacije. Teorija oskudice poslova nudi nijansiraniji pogled, ističući složenu međuovisnost između stvaranja i nestanka radnih mjesta. Ovo istraživanje doprinosi razumijevanju utjecaja digitalne transformacije na tržište rada, naglašavajući nužnost intervencija u politikama kako bi se podržala prilagodba radne snage kroz obrazovanje i usavršavanje. Ovaj rad također sugerira potrebu daljnjeg istraživanja dugoročnih učinaka tehnološke integracije u različitim sektorima te razvoj strategija za ublažavanje potencijalnih negativnih utjecaja na zaposlenost.
Klasifikacija dezinformacijskih narativa u kontekstu održivosti
Authors: Lacković Stjepan , Jemrić Ostojić Ines , Jurina Krešimir
Published: December 2024

Posljednjih nekoliko godina svjedoci smo rastućeg trenda dezinformacija, misinformacija i malinformacija koje dominiraju narativima u području održivog razvoja s potencijalno ozbiljnim posljedicama. Ovaj opasan i zabrinjavajući trend predstavlja jednaku prijetnju znanosti o održivosti kao i provedbi održivih politika od strane javnih vlasti i privatnog sektora. Dezinformacije mogu utjecati na javno mnijenje i javne politike u korist manje održivih opcija. Dezinformacije ove vrste teže potkopati napore održivosti i nužno je učinkovito se boriti protiv njih. Svrha ovog rada je klasificirati glavne dezinformacijske narative u području održivosti koji kruže javnom sferom. Dezinformacijski narativ označava kontekst s one strane konkretne dezinformacije i definiran je kao jasna poruka koja proizlazi iz dosljednog skupa sadržaja koji se može pokazati lažnim pomoću metodologije provjere činjenica. Iako akademska istraživanja o dezinformacijskim narativima u području održivosti dobivaju na snazi, nalazi su fragmentirani i potrebno je uložiti sustavnije i integriranije napore kako bi se klasificirali dominantni narativi. U ovome radu napravljen je integrativni pregled literature s ciljem otkrivanja glavnih dezinformacijskih narativa o održivosti. Konačno, glavni dezinformacijski narativi podijeljeni su u različite kategorije na temelju njihovog sadržaja. Glavni rezultati provedenog istraživanja trebali bi pružiti nužan poticaj istraživačima i praktičarima za daljnje istraživanje dezinformacijskih narativa i za rješavanje problema dezinformacija u polju održivosti.
A Survey on Routing Algorithms Based on Machine Learning
Authors: Dou Xubing , Wang Zhihui , Li Shuyun , Zhang Xinchang
Published: December 2024

With the rapid development of the Internet in today's world, many computer applications have emerged, including many new network applications, such as real-time multimedia streaming services. However, traditional computer routing algorithms have defects in these emerging network applications, so we urgently need to develop new routing algorithms to compensate for them. Machine learning technology has achieved considerable results in computer vision, image generation, and game processing. In order to further improve network performance, some research groups have introduced machine learning techniques into routing problems. Unlike traditional routing algorithms, machine learning-based routing algorithms are typically driven by data. Hence, they are more adaptable to changes in network status and can make decisions promptly. Current intelligent routing algorithms demonstrate their potential through the application of machine learning, and this idea is likely to become an indispensable part of the Internet in the future. This article first introduces machine learning technology, then introduces routing algorithms using different machine learning technologies, and finally points out the development prospects of routing algorithms based on machine learning technology.
Driving Employee Engagement through HR Automation
Authors: Westover Jonathan
Published: December 2024

This article explores how human resources can leverage automation to drive employee engagement. Drawing on both scholarly research and practical industry examples, the article outlines the key benefits of HR automation, including its ability to streamline administrative processes, enhance the employee experience, and free up HR professionals to focus on more strategic, engagement-driven initiatives. The articles covers specific use cases where automation can have the greatest impact, such as onboarding, performance management, learning and development, and HR service delivery. It also addresses the common barriers to implementing HR automation and provides strategies for overcoming them through effective change management. Finally, the brief examines the future of HR automation and its potential to transform employee engagement through emerging technologies like artificial intelligence and predictive analytics. The aim is to provide HR practitioners with a comprehensive understanding of how to harness the power of automation to cultivate a more engaged and productive workforce.
The Hidden Costs of Neglecting Employee Well-Being: A Financial Case for Prioritizing Burnout Prevention
Authors: Westover Jonathan
Published: December 2024

This article makes a compelling business case for organizations to prioritize addressing and preventing employee burnout, which has traditionally been viewed solely as a health issue. It outlines the significant "hidden costs" of burnout that directly impact the bottom line, including presenteeism, increased healthcare expenses, and reduced productivity and performance. The paper then discusses how investing in employee well-being programs can yield measurable financial benefits such as higher productivity, lower turnover, and better customer satisfaction. To build the business case, leaders are encouraged to quantify these gains using organizational data, and to implement specific practices like developing a formal wellness strategy, empowering managers, and modeling healthy behaviors from the top. By recognizing employee well-being as a strategic priority, organizations can mitigate the heavy financial toll of burnout and unlock human potential for long-term success.
Diagnóstico temprano de glaucoma de ángulo abierto en Argentina
Authors: Tripolone María Constanza , Filgueira Clemente Paz , Issolio Luis , Barrionuevo Pablo
Published: December 2024

Objetivo: Conocer la valoración de los oftalmólogos sobre las metodologías disponibles para el diagnóstico temprano de glaucoma de ángulo abierto (GAA), y evaluar la necesidad de nuevos métodos para la exploración funcional de la retina.
Métodos: Se realizó un estudio transversal basado en una encuesta dirigida a oftalmólogos residentes en Argentina. La encuesta se realizó en formato virtual e incluyó cuatro preguntas que indagaron sobre el diagnóstico de GAA desde el punto de vista metodológico/tecnológico.
Resultados: Un total de 65 oftalmólogos completaron el cuestionario. El 54% de los encuestados consideró que se debe trabajar en metodologías que permitan anticipar aún más tempranamente el GAA. Para mejorar el diagnóstico, el 66% señaló que se debe trabajar tanto en metodologías que evalúen lo estructural como lo funcional de la retina. El 37% indicó tener conocimiento sobre tecnologías de evaluación funcional de las capas de la retina. Finalmente, el 78% considera que la evaluación funcional de las capas de la retina es “muy importante” para el diagnóstico.
Conclusiones: Esta encuesta muestra, desde la perspectiva de los oftalmólogos, la necesidad de contar con herramientas de valoración funcional para mejorar el diagnóstico de GAA en etapas tempranas. Las tecnologías disponibles de exploración funcional, carecen de sensibilidad en etapas tempranas, señalando la importancia de desarrollar nuevas metodologías funcionales.
Presbyopia and age-related Macular degeneration
Authors: Szeps Abel , Suarez Juan Manuel , Bordese Valeria , Acerbi Matías , Albertazzi Roberto , Iribarren Guillermo , Luna Pinto José , Lanca Carla , Iribarren Rafael , Saravia Mario
Published: December 2024

Objective: To evaluate the design of spectacle lenses and daily spectacle use in presbyopes over 60 years of age with and without age-related macular degeneration (AMD). 
Methods: A cross sectional study was designed, and a web questionnaire was distributed to a two ophthalmological centers database of presbyopic outpatients over 60 years of age with and without AMD. The questionnaire included data of monofocal, bifocal or multifocal spectacle use, and asked whether the subjects used their spectacles full day or only for reading purposes. A multivariate logistic regression analysis was performed to test whether full or part day spectacle use, and use of multifocals or bifocals were associated with the odds of AMD, controlling by age, gender and cataract surgery.
Results: The sample included 780 subjects, of which 379 (48.6%) had AMD; 61.3% were women. Glasses were used only for near vision by 60.9% of the individuals, while 26.0% used either bifocals or multifocals as full time wearers. Increasing age (Odds ratio [OR]: 1.04, 95% CI 1.02 to 1.06, p<0.001), undergoing cataract surgery (OR: 3.10, 95%CI 2.07 to 4.65, p<0.001) and wearing glasses all day (OR: 1.94, 95%CI 1.29 to 2.91, p=0.001) were associated with the presence of AMD. 
Conclusions: We found an association between the presence of AMD and full-time spectacle wear. Further prospective controlled studies are necessary to study the link between spectacle use and AMD development.
Herpes Zóster Oftálmico en paciente inmunocomprometido
Authors: Reviglio María Virginia , Osaba Matías , Nigatake Yukari , Rosiere Gustavo , Reviglio Víctor Eduardo
Published: December 2024

ObjetivoInformar el caso de una paciente de sexo femenino inmunocomprometida quedesarrolló herpes zóster oftálmico, requiriendo manejo intravenoso debido a la afectación dermatológica y neurooftalmológica, con recuperación parcial tras el tratamiento.
Caso ClínicoPaciente femenina de 60 años ingresada por desnutrición severa y síndrome diarreico crónico, presentando caquexia y desequilibrio hidroelectrolítico. Antecedentes de celiaquía, cardiopatía dilatada y pancreatitis, en tratamiento con corticoides sistémicos (Meprednisona 40 mg/dia). Durante la hospitalización, desarrolló dolor ocular izquierdo y edema bipalpebral, diagnosticándose herpes zóster oftálmico. Se inició tratamiento antiviral con Aciclovir oral de 800 mg cada 6 horas y ganciclovir ungüento oftalmológico.Debido a la falta de mejoría, se administró terapia intravenosa antiviral (Aciclovir500 mg/8 horas) y antibiótica (Ceftriaxona 2 gr/24 horas + Clindamicina 600 mg/8 horas).Tras alta hospitalaria, la paciente presentó neuralgia del trigémino y oftalmoplejía,requiriendo manejo adicional. Resonancia magnética mostró inflamación del nervio óptico y estructuras adyacentes. A pesar de que la paciente se negó a una biopsia de lesión inflamatoria cerebral, mejoró sintomáticamente. Continuó con fotofobia e incapacidad de abducción ocular, con agudeza visual reducida. Se estableció tratamiento tópico y corrección visual, y se programaron seguimientos regulares.ConclusiónEl manejo de herpes zóster oftálmico en pacientes inmunocomprometidos tal como en el caso descrito con desnutrición severa y otras comorbilidades requiere un abordaje multidisciplinario y tratamiento intensivo. A pesar de la terapia antiviral y antibiótica, las complicaciones neurológicas pueden persistir, subrayando la necesidad de seguimiento continuo y cuidado personalizado.
ángel
Authors: López Asensio Emilio , Guaycochea Mariana , Osaba Matías , Muñoz Agustina Gabriela , Macció Juan Pablo
Published: December 2024

Posterior al globo ocular, los axones que componen al nervio óptico están rodeados por una capa de mielina producida por los oligodendrocitos....
Cada dioptría cuenta
Authors: Kotlik Carlos A.
Published: December 2024

Dentro de la oftalmología, el conocimiento que tenemos sobre la enfermedad de la miopía se ha ideo incrementando en gran medida en las últimas cuatro a 5 décadas. Se están pudiendo responder diferentes preguntas de investigación y a la vez se están logrando terapéuticas que tienden a prevenir o enlentecer la progresión de la miopía. La miopía está aumentando en el mundo por diversos factores, sobre todo aquellos relacionados con estilo de vida y medio ambiente, siendo estos factores de riesgo modificables. Tener más miopía a lo largo de la vida significa también tener más riesgo de perder la visión por patologías secundarias. Por eso, cada dipotría cuenta y en este trabajo de revisión, se hará un breve repaso a las evidencias y experiencias desarrolladas en la práctica asistencial, den Mendoza, Argentina.
Economic Evaluation of Mental Health Interventions
Authors:   Quaid-i-Azam University, Islamabad, Pakistan, Shah Syed
Published: December 2024

This narrative review evaluates the cost-effectiveness of various mental health interventions, including cognitive behavioral therapy cognitive behavioral therapy and cognitive behavioral treatment, pharmacological treatments selective serotonin reuptake inhibitors, group therapy, Assertive Community Treatment (ACT), and digital mental health solutions. A broad range of studies from the past 20 years was included, with a focus on interventions for depression, anxiety disorders, and schizophrenia. Studies were selected based on economic evaluation methods (cost-effectiveness, cost-utility, and cost-benefit) and relevance to public healthcare systems. The findings indicate that cognitive behavioral therapy and ACT are highly cost-effective, with incremental cost-effectiveness ratios of $18,000 and $19,000 per quality-adjusted life year, respectively. Digital interventions, such as telemedicine and mental health apps, showed significant cost savings, particularly in underserved populations. Limitations include a lack of longitudinal studies and underrepresentation of low- and middle-income countries. Future research should focus on long-term outcomes and scalability of digital interventions.
PENGARUH DIGITAL MARKETING DAN INOVASI PRODUKTERHADAP PENDAPATAN UMKM (STUDI KASUS PADA UMKM KEC.NATAR KAB. LAMPUNG SELATAN)
Authors: Rizky Nova Dwi , Isabella Astrid Aprica , Sari Pipit Novila
Published: December 2024

One that plays an important role in the economic recovery process is UMKM. The characteristics of UMKM can be said to be unique, because their numbers dominate the structure of the Indonesian economy, and continue to grow nationally and absorb 97% of the total workforce. This study aims to find out how Digital Marketing and Innovation Influence Products on UMKM income (Case Study on UMKM in Natar District, South Lampung Regrency).
The research method used in associative quantitative method with a survey approach. The population in this study were business actors in Natar District, South Lampung Regrency with a total of 30 business actors. The sample used in this study used a census technique because the total population was less than 100. The data collection techniques were carried out trough observation, interviews, and questionnaires. The results of the study show that there is positive and significant influence of digital marketing and product innovation on UMKM income in Natar District South Lampung Regrency, namely 0,453 or 45,3% with the acquisition of Fcount > Ftable or 11.189 > 3,32 and a significance value of 0,000 < 0,05.
SISTEM INFORMASI PERSEDIAAN BARANG JADI PADA PT. SAP BERBASIS DESKTOP
Authors: Octanza Tahta Rizaldi , Sudrajat Ari
Published: December 2024

The aim of this research is to carry out a series of stages starting from analyzing, designing, implementing and testing the Finished Goods Inventory Information System at PT. SAP. The research method used is the waterfall method and the analysis used is PIECES analysis, with system testing using black-box testing. The programming language used is Microsoft Visual Visual Studio with Microsoft Access as the database. It is known that the resulting inventory information system is a system solution that has been running previously, the recording process of which is still semi-computerized using Microsoft Excel so that the inventory data processing process is not appropriate. Based on the results of the information system that has been created, it can be concluded that, with a computerized and integrated database system, it can help and make it easier for warehouse admins to input goods data, incoming goods data and outgoing goods data that occur at PT. SAP, minimizes errors and makes data input easier. Based on the overall calculation of the (UAT) User Acceptance Test by the user, the system testing using Black-box received an assessment of 91.43% which was categorized as Very Good.