bluuebunny/crossref_metadata_2025 huggingface dataset:
KARAKTERISTIK DAN TATALAKSANA SINDROM EPILEPSI: SEBUAH TINJAUAN LITERATUR
Authors: Putri Derby Ayudhia Utami Iskandar , Sari Riri Gusnita
Published: March 2024

Definisi dan klasifikasi sindrom epilepsi pertama kali disampaikan oleh International League Against Epilepsy (ILAE) tahun 1985. Menurut ILAE sindrom epilepsi merupakan gangguan epilepsi yang ditandai dengan sekelompok tanda dan gejala, yang dapat terjadi bersamaan. Gejala bergantung pada usia dan serangkaian penyakit penyerta tertentu.  Penulis bertujuan menggabungkan berbagai literatur terkini mengenai sindrom epilepsi. Literatur diambil menggunakan database Google Scholar, PubMed, Cochrane Library dalam kurun waktu 4 (empat) tahun, 2019-2023. Studi yang diikutsertakan ke dalam literatur yang sesuai dengan kriteria inklusi meliputi studi yang menjelaskan mengenai sindrom epilepsi dan karakteristiknya. Klasifikasi sindrom epilepsi dibagi berdasarkan jenis kejang dan onset usia. Setiap jenis memiliki karakteristik dan tatalaksana yang berbeda. Sindrom epilepsi pada masa anak yang paling sering dijumpai meliputi, Generalized Tonic-Clonic Seizures Alone/ GTCSA, Childhood Absence Epilepsy/ CAE, Lennox-Gastaut Syndrome/ LGS, West syndrome/ WS, Self-Limited Childhood Epilepsy with Centrotemporal Spikes/ SLCECTS. Dapat disimpulkan bahwa inisiasi pengobatan antikejang pada sindrom epilepsi bergantung pada usia dan efektivitas yang berbeda dari obat antiepilepsi.
Percepción de los estudiantes ante la virtualización de las aulas en la Universidad Autónoma de Campeche
Authors: González Mayté Cadena , Bojórquez María Alejandra Sarmiento , Rosado Juan Fernando Casanova
Published: March 2024

Ante la pandemia de COVID-19 y el cierre de las escuelas en el año 2 020, la virtualización de las aulas fue la solución que permitió la continuidad del proceso educativo. La Universidad Autónoma de Campeche, al finalizar la emergencia y regresar a clases presenciales determina que se seguirá utilizando las aulas virtuales durante los siguientes periodos de clases como apoyo para la enseñanza-aprendizaje. Este trabajo tiene como objetivo conocer la percepción sobre la virtualización de las aulas, de los alumnos de la escuela preparatoria Dr. Nazario Víctor Montejo Godoy, después de la pandemia de COVID-19. La investigación realizada es de tipo descriptivo, y el diseño es el no experimental con corte transversal. En conclusión, los alumnos se sintieron satisfechos; el 96.1% indica un buen nivel de satisfacción de la virtualización realizada considerando buena la metodología empleada por los docentes, los recursos y materiales didácticos adecuados y un buen sistema de evaluación.  Ante los resultados se busca fortalecer las estrategias utilizadas para una mejora continua y el desarrollo de las habilidades digitales.
Jumbo Flying Squid Distribution within Anticyclonic Eddies under Anomalous Climatic Conditions
Authors: Jin Pengchao , Fan Jiangtao , Wu Xiaoci , Du Yanling , Yu Wei
Published: March 2024

Anticyclonic eddies are widely distributed off Peru, producing obvious effects on climate-environment-sensitive jumbo flying squid
Dosidicus gigas
. However, how the habitat of
D. gigas
changes within anticyclonic eddies during El Niño events is still unknown. Therefore, this study constructed a habitat model with different weights and screened the optimal performance model using fishery data from September to December during 2015 to 2019, as well as vertical water temperature data (sea surface temperature and 50 m water depth temperature) and surface chlorophyll concentration data (Chl-a). Then, combined with the eddy tracking dataset, the differences in the variation of resource abundance and habitat of
D. gigas
within the anticyclonic eddy between the 2015 El Niño year and the 2019 normal year were further comparatively analyzed based on the optimal habitat model. Compared with the normal year of 2019, the 2015 El Niño event occurred with a lower intensity of eddy activity, and both temperature in the fishing ground and near-surface sea water temperature within the anticyclonic eddy became warmer, with a small decrease in Chl-a; the percentage of suitable near-surface water temperature within the anticyclonic eddies decreased significantly, and suitable Chl-a decreased slightly; the suitable habitat for
D. gigas
was reduced dramatically, which was unfavorable to
D. gigas
survival. Our finding suggested that that anomalous climatic events can have an impact on eddy strength, as well as on the suitable environment and habitat within the anticyclonic eddies, resulting in variations in the abundance of
D. gigas
.
Association between Body Mass Index and Brain Health in Adults: A 16-Year Population-Based Cohort and Mendelian Randomization Study
Authors: Lv Han , Zeng Na , Li Mengyi , Sun Jing , Wu Ning , Xu Mingze , Chen Qian , Zhao Xinyu , Chen Shuohua , Liu Wenjuan , Li Xiaoshuai , Zhao Pengfei , Wintermark Max , Hui Ying , Li Jing , Wu Shouling , Wang Zhenchang
Published: March 2024

Background:
The cumulative effect of body mass index (BMI) on brain health remains ill-defined. The effects of overweight on brain health across different age groups need clarification. We analyzed the effect of cumulative BMI on neuroimaging features of brain health in adults of different ages.
Methods:
This study was based on a multicenter, community-based cohort study. We modeled the trajectories of BMI over 16 years to evaluate cumulative exposure. Multimodality neuroimaging data were collected once for volumetric measurements of the brain macrostructure, white matter hyperintensity (WMH), and brain microstructure. We used a generalized linear model to evaluate the association between cumulative BMI and neuroimaging features. Two-sample Mendelian randomization analysis was performed using summary level of BMI genetic data from 681,275 individuals and neuroimaging genetic data from 33,224 individuals to analyze the causal relationships.
Results:
Clinical and neuroimaging data were obtained from 1,074 adults (25 to 83 years). For adults aged under 45 years, brain volume differences in participants with a cumulative BMI of >26.2 kg/m
2
corresponded to 12.0 years [95% confidence interval (CI), 3.0 to 20.0] of brain aging. Differences in WMH were statistically substantial for participants aged over 60 years, with a 6.0-ml (95% CI, 1.5 to 10.5) larger volume. Genetic analysis indicated causal relationships between high BMI and smaller gray matter and higher fractional anisotropy in projection fibers.
Conclusion:
High cumulative BMI is associated with smaller brain volume, larger volume of white matter lesions, and abnormal microstructural integrity. Adults younger than 45 years are suggested to maintain their BMI below 26.2 kg/m
2
for better brain health.
Trial Registration:
This study was registered on clinicaltrials.gov (Clinical Indicators and Brain Image Data: A Cohort Study Based on Kailuan Cohort; No. NCT05453877;
https://clinicaltrials.gov/ct2/show/NCT05453877
).
Thermal and Magnetic Dual-Responsive Catheter-Assisted Shape Memory Microrobots for Multistage Vascular Embolization
Authors: Peng Qianbi , Wang Shu , Han Jianguo , Huang Chenyang , Yu Hengyuan , Li Dong , Qiu Ming , Cheng Si , Wu Chong , Cai Mingxue , Fu Shixiong , Chen Binghan , Wu Xinyu , Du Shiwei , Xu Tiantian
Published: March 2024

Catheters navigating through complex vessels, such as sharp turns or multiple U-turns, remain challenging for vascular embolization. Here, we propose a novel multistage vascular embolization strategy for hard-to-reach vessels that releases untethered swimming shape-memory magnetic microrobots (SMMs) from the prior catheter to the vessel bifurcation. SMMs, made of organo-gel with magnetic particles, ensure biocompatibility, radiopacity, thrombosis, and fast thermal and magnetic responses. An SMM is initially a linear shape with a 0.5-mm diameter at 20 °C inserted in a catheter. It transforms into a predetermined helix within 2 s at 38 °C blood temperature after being pushed out of the catheter into the blood. SMMs enable agile swimming in confined and tortuous vessels and can swim upstream using helical propulsion with rotating magnetic fields. Moreover, we validated this multistage vascular embolization in living rabbits, completing 100-cm travel and renal artery embolization in 2 min. After 4 weeks, the SMMs maintained the embolic position, and the kidney volume decreased by 36%.
N6-Methyladenosine in Cell-Fate Determination of BMSCs: From Mechanism to Applications
Authors: Zhang Qingyu , Li Junyou , Wang Cheng , Li Zhizhuo , Luo Pan , Gao Fuqiang , Sun Wei
Published: March 2024

The methylation of adenosine base at the nitrogen-6 position is referred to as “N6-methyladenosine (m
6
A)” and is one of the most prevalent epigenetic modifications in eukaryotic mRNA and noncoding RNA (ncRNA). Various m
6
A complex components known as “writers,” “erasers,” and “readers” are involved in the function of m
6
A. Numerous studies have demonstrated that m
6
A plays a crucial role in facilitating communication between different cell types, hence influencing the progression of diverse physiological and pathological phenomena. In recent years, a multitude of functions and molecular pathways linked to m
6
A have been identified in the osteogenic, adipogenic, and chondrogenic differentiation of bone mesenchymal stem cells (BMSCs). Nevertheless, a comprehensive summary of these findings has yet to be provided. In this review, we primarily examined the m
6
A alteration of transcripts associated with transcription factors (TFs), as well as other crucial genes and pathways that are involved in the differentiation of BMSCs. Meanwhile, the mutual interactive network between m
6
A modification, miRNAs, and lncRNAs was intensively elucidated. In the last section, given the beneficial effect of m
6
A modification in osteogenesis and chondrogenesis of BMSCs, we expounded upon the potential utility of m
6
A-related therapeutic interventions in the identification and management of human musculoskeletal disorders manifesting bone and cartilage destruction, such as osteoporosis, osteomyelitis, osteoarthritis, and bone defect.
Cross-Modal Graph Semantic Communication Assisted by Generative AI in the Metaverse for 6G
Authors: Chen Mingkai , Liu Minghao , Wang Congyan , Song Xingnuo , Zhang Zhe , Xie Yannan , Wang Lei
Published: March 2024

Recently, the development of the Metaverse has become a frontier spotlight, which is an important demonstration of the integration innovation of advanced technologies in the Internet. Moreover, artificial intelligence (AI) and 6G communications will be widely used in our daily lives. However, the effective interactions with the representations of multimodal data among users via 6G communications is the main challenge in the Metaverse. In this work, we introduce an intelligent cross-modal graph semantic communication approach based on generative AI and 3-dimensional (3D) point clouds to improve the diversity of multimodal representations in the Metaverse. Using a graph neural network, multimodal data can be recorded by key semantic features related to the real scenarios. Then, we compress the semantic features using a graph transformer encoder at the transmitter, which can extract the semantic representations through the cross-modal attention mechanisms. Next, we leverage a graph semantic validation mechanism to guarantee the exactness of the overall data at the receiver. Furthermore, we adopt generative AI to regenerate multimodal data in virtual scenarios. Simultaneously, a novel 3D generative reconstruction network is constructed from the 3D point clouds, which can transfer the data from images to 3D models, and we infer the multimodal data into the 3D models to increase realism in virtual scenarios. Finally, the experiment results demonstrate that cross-modal graph semantic communication, assisted by generative AI, has substantial potential for enhancing user interactions in the 6G communications and Metaverse.
Distribution, Evolution, and Origin of the Lunar Energetic Particles
Authors: Zhang ChenXuan , Zhang XianGuo , Cao JinBin , Li Lei , Zhang XiaoPing , Guo JingNan , Xie LiangHai , Zhang ShenYi , Wang XinYue
Published: March 2024

Various kinds of energetic particles can directly and continuously interact with the lunar surface since there is no atmosphere and no global magnetic field on the Moon. How energetic particles distribute on the Moon and what are their roles in the space weathering caused by the interactions between energetic particles and the lunar surface are the essential problems that need to be solved urgently in lunar science. In this paper, the research status and related scientific problems of the origin, distribution, and evolution of lunar energetic particles are summarized. The lunar exploration programs proposed by different countries and organizations are listed, and directions for future development are also discussed in this paper. Finally, based on the open questions and future focuses, we put forward several suggestions about China’s future lunar exploration programs and technical specifications of scientific payloads.
Orman Gülü (Rhododendron ssp.) Çeliklerinin Köklenmeleri Üzerine Farklı Uygulamaların Etkileri
Authors: ALTUN Bahadır , ÇELİK Hüseyin
Published: March 2024

Bu araştırma, Türkiye doğal orman gülü türlerinin (Rhododednron ponticum L., R. luteum Sweet, R. caucasicum Pallas, R. simirnovii Trautv ve R. ungernii Trautv) çeliklerinin köklenme oranları (%) üzerine farklı çelik alma dönemi, farklı IBA dozlarının ve köklendirme ortamlarının etkilerini belirlemek amacıyla yürütülmüştür. Ağustos ayının sonu, Ekim ayının ilk yarısı ve Kasım ayının ikinci yarısında alınan tepe çelikleri, İndol-3-Bütirik Asit (IBA)’in 0, 2000 ppm, 4000 ppm ve 8000 ppm dozlarına tabi tutularak alttan ısıtmalı tavalarda ve mistleme sulama altında köklendirme ortamlarına dikilmişlerdir. Köklendirme ortamı olarak asidik torf+perlit (3:1) ve perlit ortamı kullanılmıştır. Araştırma sonucunda yıllara göre değişmekle beraber en yüksek köklenme oranları R. ponticum, R. smirnovii ve R. ungernii türlerinde asidik torf+perlit (3:1) ortamında (sırasıyla % 75.83, %59.17 ve %25), R. luteum ve R. caucasicum türlerinde ise perlit ortamında (sırasıyla %64.17 ve %29.17) olduğu tespit edilmiştir. Orman gülü çeliklerinin köklenme seviyelerinin; türe, çelik alma dönemine, köklenme ortamına, kullanılan IBA dozuna ve yıllara bağlı olarak değişkenlik gösterdiği belirlenmiştir.
A Comparative Evaluation of a Compressed Ignition Engine Fuelled with Nano Methyl Esters of Punnai and Waste Cooking Oil
Authors: Subramaniam D. , Aslam Sheriff F. , Dinesh Kumar P. , Rineeth G.K.
Published: March 2024

In this experimental work focused on, the performance, emission, and combustion characteristics of Nano methyl esters of Punnai oil and Waste Cooking oil, and their diesel blends in a Compressed Ignition were experimentally tested. In the study, Nano Punnai oil methyl esters (NPOME), and Nano Waste Cooking Oil Methyl Esters (NWCOME) were prepared by the transesterification process. The Bio diesel-diesel blends were prepared by mixing 10%, 30%, 50%, and 70% of biodiesel with diesel. The effects of two nano methyl esters and their diesel blends on engine performance, combustion, and exhaust emissions are tested at different engine loads. Experimental results concluded that up to 30% of no methyl esters did not affect the performance, combustion, and emissions characteristics. On the other hand, above B30 (30% Biodiesel with 70% diesel) a reduction in performance, combustion, and emission characteristics is clear from the study.
Perbandingan Metode Esktraksi Terhadap Rendemen Ekstrak Batang Turi (Sesbania Grandiflora L.) Dengan Menggunakan Metode Maserasi Dan Sokhletasi
Authors: Wijaya Heri , Jubaidah Siti , Rukayyah Rukayyah
Published: March 2024

ABSTRAKBatang turi (Sesbania grandiflora L) merupakan bagian tumbuhan yang dapat digunakan sebagai obat kumur dan mengandung zat saponin, flavonoid, polifenol, dan tanin. Senyawa dari tumbuhan dapat diperoleh dengan cara ekstraksi. Rendemen rendemen ekstrak dalam proses ekstraksi dapat dipengaruhi oleh beberapa faktor, seperti metode ekstraksi, waktu ekstraksi. Tujuan dari penelitian ini adalah untuk mengetahui rendemen rendemen ekstrak batang turi menggunakan metode maserasi dan sokletasi. Penelitian yang dilakukan adalah penelitian eksperimen. Tahapan penelitian meliputi pengambilan sampel, penentuan tanaman, pengolahan sampel, proses ekstraksi maserasi dan sokletasi, perhitungan rendemen rendemen, penentuan kadar air, penapisan fitokimia. Hasil penelitian menunjukkan bahwa metode sokletasi menghasilkan rata-rata nilai rendemen rendemen yang lebih tinggi yaitu sebesar 7,76% dan rendemen hasil maserasi dengan nilai rendemen rata-rata sebesar 6,13%. Skrining fitokimia batang turi menunjukkan hasil positif.Â
Relation between Body Mass Index and Knee Osteoarthritis in Pre-Elderly to Elderly at Orthopedic Poly of Dr. Mohamad Soewandhie Regional Public Hospital Surabaya
Authors: Santosa Yoga Prana Putra , Wartiningsih Minarni , Sasono Bimo
Published: March 2024

Osteoarthritis is a degenerative joint disease characterized by painful joints, particularly prevalent in older individuals, attributed to mild inflammation resulting from bone-end friction. A study conducted in Surakarta revealed a 4.9-fold increase in osteoarthritis risk among individuals with a BMI >25 compared to those with a BMI of 18.5-25.0. This research aims to investigate the association between knee osteoarthritis and BMI among elderly patients at the orthopedic outpatient clinic of Sesyapdhio Hospital, Surabaya. Using cross-sectional observational analysis, osteoarthritis patients were identified. The findings indicate a correlation between higher BMI and increased severity of osteoarthritis, contrasting with milder cases observed in individuals with normal BMI. Spearman's rank correlation review revealed a strong positive correlation (r=0.554) between BMI and osteoarthritis severity at Sexygandhio Hospital Surabaya. This study's unique contribution lies in its focused exploration of the relationship between BMI and osteoarthritis severity in elderly patients, offering insights into potential interventions tailored to BMI-specific risk profiles.
Keeping an Eye Out for Immunotherapy Toxicity: A Case of Unilateral Ptosis Caused by Ipilimumab/Nivolumab Therapy
Authors: Jazieh Khalid , Kottschade Lisa , Dimou Anastasios
Published: March 2024

Despite ocular adverse events from immune checkpoint inhibitors being uncommon, they are still important complications to be aware of. We present the case of metastatic melanoma on ipilimumab/nivolumab in a patient who developed immunotherapy complications with delayed diagnosis because the only presenting symptom was unilateral ptosis. We reviewed the literature for relevant and important ocular and neurological complications of immune checkpoint inhibitors.
Concrete Bridge Deck Crack Sealing
Authors:   University of Illinois Chicago, Issa Mohsen , Alawieh Ali ,   University of Illinois Chicago, Daoud Hussein ,   University of Illinois Chicago
Published: March 2024

Bridge decks are prone to various types of cracking due to a combination of factors, including traffic loads, temperature variations, moisture, and chemical exposure. This report tackles the critical issue of bridge deck cracking by systematically dissecting the problem, exploring various crack types, and emphasizing the crucial inspection and categorization of cracks for effective remediation planning. The report focuses on the selection of appropriate sealants, considering regional conditions. It delves into remediation treatments, offering a spectrum of options based on National Bridge Inventory ratings, deck conditions, and crack characteristics. Additionally, the report classifies sealant products and introduces a cost-analysis framework, promoting well-rounded decision-making that balances short-term project costs with ongoing maintenance expenses. Serving as a valuable resource, the report equips decision-makers with knowledge and tools to optimize resource allocation, enhance bridge deck integrity, and improve maintenance practices.
Exérese de cistoadenoma associado à glândula parótida: Relato de caso clínico
Authors: Silva Fábia Rayanne Oliveira e , Santos Silva Mariana Roberta , De Medeiros Albuquerque Maria Eduarda , De Holanda Vasconcellos Ricardo José , Ribeiro Lilian Nunes , De Pontes Felix Larissa Polyanna , Sant'Ana Maria Eduarda Cezar de , Araújo Emerllyn Shayane Martins de , Ugarte Rodrigo Gonzalo Valdivia , Melo Filho Sérgio Murilo Cordeiro de , Da Costa Araújo Fábio Andrey , De Oliveira e Silva Emanuel Dias
Published: March 2024

O cistoadenoma de glândula salivar é uma neoplasia epitelial benigna rara; Histologicamente,  apresenta múltiplas cavidades císticas contendo projeções papilares intraluminais e áreas de diferenciação oncocítica. A terapia de eleição é a excisão cirúrgica e casos de recidiva estão associados a remoção incompleta da lesão. Objetivo: O presente trabalho visa relatar um caso clínico raro de cistoadenoma da glândula parótida em um paciente do sexo masculino jovem, descrevendo os aspectos clínicos e histopatológicos da lesão e a abordagem terapêutica realizada.  Relato de caso: Paciente do sexo masculino, 25 anos, relatou aumento de volume assintomático na região de glândula parótida direita há 8 meses. O paciente foi tratado com excisão cirúrgica da lesão e análise anatomopatológica concluiu cistoadenoma da glândula parótida. O paciente encontra-se em acompanhamento sem sinais clínicos de recidiva. Conclusão: Apesar de ser uma patologia rara das glândulas salivares, o conhecimento das patologias das glândulas salivares associados a correta indicação de exames imaginológicos e biópsias são indicadores de um prognóstico previsível. A excisão cirúrgica se mostra como o tratamento de eleição para esta patologia, que apresenta prognóstico favorável e poucos relatos de recidiva associados à excisão cirúrgica incompleta da lesão, dificultada pela ausência de cápsula que a delimite.
MANEJO DA GRAVIDEZ DE RISCO E ASSISTÊNCIA AO PRÉ-NATAL
Authors: Ditzel Adriana Nunes , Júnior Eliel Pessôa de Souza , Breitkreitz Victória Schneider , Andrade Carolina Okuyama , Valente Maria Clara , Lima Gabriel Ferreira , Andrade Beatriz Carrijo , Dias Zaine Dupim , Brasil Bruno Sergio Costa , Castro Nathalia Salvagni , Neto Antônio Carlos de Araújo , Santos Luciana ferreira dos , Filho Artur Clímaco Da Silva , Sanches Juliana Dias Gondim
Published: March 2024

O manejo da gravidez de risco envolve acompanhamento médico mais frequente, exames adicionais e, às vezes, repouso. A assistência ao pré-natal é crucial para monitorar a saúde da mãe e do bebê, permitindo intervenções precoces se necessário. Recomenda-se seguir as orientações médicas e manter um estilo de vida saudável durante esse período. O pré-natal é o cuidado médico que uma mulher recebe durante a gestação para garantir uma gravidez saudável. Isso inclui consultas regulares, exames, orientações sobre nutrição, atividade física e preparação para o parto. É fundamental para monitorar o desenvolvimento do feto e tratar qualquer problema de saúde materna que possa surgir. O objetivo desse artigo foi compreender a importância do pré-natal e além disso evidenciar as complicações de uma gravidez de risco. Foram utilizadas as bases de dados Pubmed, Scielo, Medline, Scopus e Web of Science,   com artigos publicados nos idiomas inglês ou português. Em conclusão, o pré-natal é uma parte essencial do cuidado materno durante a gravidez, assegurando um acompanhamento adequado da saúde da mãe e do feto. Ao seguir as orientações médicas, realizar exames regulares e adotar um estilo de vida saudável, contribuímos para o bem-estar geral, favorecendo um parto seguro e a saúde a longo prazo tanto da mãe quanto do bebê.
Liderança Governamental do Poder Executivo Municipal de Parintins (AM) e suas Implicações na Gestão da Pandemia da Covid-19
Authors: Sá Lundrigs Pantoja de , Emmendoerfer Magnus Luiz , Mediotte Elias José , Schneider Locatelli Débora Regina , Ribeiro Adagenor Lobato , Barbosa Maria de Fátima Nobrega
Published: March 2024

O propósito deste artigo é apresentar o tipo de liderança adotado pelo Executivo Municipal de Parintins (AM) para o enfrentamento da crise sanitária provocada pela pandemia da Covid-19 no âmbito municipal. Pesquisaram-se informações publicizadas das ações para o enfrentamento da doença pela Gestão municipal, procurando identificar as implicações decorrentes dessas operações nos campos político, social e econômico. Com a abordagem qualitativa no estudo de caso, se obteve respostas às pressuposições feitas quanto à promoção de gerenciamento de ações de políticas assertivas e à geração de resoluções satisfatórias ao combate à pandemia. Os principais resultados da investigação apontaram a importância da liderança para a condução das ações de combate à doença e às suas implicações nos campos político, social e econômico, destacando-se as competências gerenciais para o desenvolvimento de pessoas e de equipes, expressos por Decretos Municipais, Atos de Gestão, Relatórios, Planos de Combate ao Coronavírus. Conclui-se que o estilo esperado de liderança democrática para o cenário pandêmico de Parintins se desenvolveu com ações efetivas e diferenciadas, possibilitando aproveitar a experiência de uma liderança de um município, que é uma ilha no meio do Amazonas, com dificuldades logísticas muito diversificadas e que teve que desenvolver competências em nível local para suprir suas necessidades. Tais ações indicam que o estilo de liderança democrática, em situação de crise, remete à criatividade de inovação para encurtar os tramites burocráticos, não desperdiçando recursos e, ao mesmo tempo, trazendo uma resposta que foi considerada positiva pela população.
OPTIMASI SUHU ANNEALING PROSES PCR AMPLIFIKASI GEN ATP1 A1 SAPI JABRES DAN GALEKAN
Authors: Dewi Khosiya Robba  , Tuwi Ramsiati Dyah , Indah Wulansari Wahyuni , Chanafi Mochammad , Asepriyadi  , Ariyanti Rina , Nihaya Ullin
Published: March 2024

Adanya kenaikan suhu pada lingkungan sekitar ternak sapi lokal Jabres dan sapi Galekan memiliki efek negatif terhadap perkembangan, pertumbuhan, produktivitas dan reproduksi-nya. Untuk itu, diperlukan metode untuk mengetahui kemampuan adaptasi sapi terhadap cekaman panas. Pada penelitian ini, sampel yang digunakan adalah DNA sapi lokal Jabres dan sapi Galekan dengan menggunakan metode penelitian molekuler in-vitro seperti isolasi DNA, Amplifikasi gen ATP1 A1 dengan Optimasi PCR, elektroforesis dan hasil visualisasinya. Isolasi DNA pada 8 sampel darah sapi Jabres dan sapi Galekan menunjukkan hasil isolasi DNA yang tepat dan sesuai dengan ditandai munculnya pita DNA yang terang dan tebal. Sedangkan, suhu annealing pada proses optimasi PCR yang digunakan untuk menempelkan primer forward ATP1 A1 5'- TCC CCA AGC TAG TGA CCA AG -3' dan primer reverse ATP1 A1 5'- TCT GTG GCT CTG ATT CTC CC -3' adalah 57oC, 57,3oC, 58,1oC, 59,3oC, 60,7oC, 61,9oC, 62,7oC, 63oC. Hasil optimasi PCR dielektroforesis dengan 100 volt selama 35 menit kemudian gel agarose hasil elektroforesis divisualisasikan menggunakan UV transilluminator sehingga didapatkan hasil suhu annealing yang optimal pada suhu 57 oC.
 
Kata Kunci : Sapi, PCR, gen ATP1A1, Annealing
POTENSI DAYA DUKUNG LIMBAH TANAMAN PANGAN DAN HIJAUAN SEBAGAI SUMBER PAKAN TERNAK RUMINANSIA DI KECAMATAN PANCA RIJANG DAN KECAMATAN KULO KABUPATEN SIDENRENG RAPPANG
Authors: Yusuf Subaedy , Hazairin Zubair  , Arif Samsu
Published: March 2024

Penelitian ini bertujuan untuk mengetahui potensi daya dukung limbah tanaman pangan dan hijauan di Kecamatan Pancarijang dan Kulo, Kabupaten Sidenreng Rappang sebagai sumber pemetaan wilayah terhadap pengembangan peternakan. Penelitian ini dilakukan menggunakan data sekunder yaitu populasi ternak ruminansia dan luas panen tanaman pangan dan hijauan. Hasil penelitian menunjukkan produksi bahan kering limbah tanaman pangan dan hijauan di Kecamatan Pancarijang yaitu 21.661,77 ton bahan kering (BK) dan Kecamatan Kulo sebesar 28.837,86 ton BK. Produksi limbah tanaman pangan dan hijauan tertinggi berasal dari Desa Rijangpanua, Kecamatan Kulo yaitu sebesar 8964,48 ton BK. Daya dukung untuk pakan yang berasal dari limbah jerami padi, jagung dan hijauan yaitu sebanyak 19.001,56 satuan ternak (ST) di Kecamatan Pancarijang dan 25.296,37 ST di Kecamatan Kulo. Hasil analisis location quotient (LQ) di Kecamatan Pancarijang menunjukkan LQ >1 untuk jerami padi terdapat berada pada lima Desa yaitu Rappang, Lalebata, Macorawalie, Kadidi, dan Timureengpanua, sementara Desa tempat program DKS memiliki LQ <1 untuk jerami padi, namun mempunyai keunggulan LQ>1 berasal dari jerami jagung dan hijauan. Demikian nilai LQ >1 di Kecamatan Kulo untuk jerami padi terdapat empat Desa yaitu Kulo, Maddenra, Bina Baru dan Abbokongang, sedangkan Desa Mario dan Rijangpanua memiliki LQ<1. Namun, kedua Desa tersebut memiliki keunggulan yang sama dengan wilayah DKS di Kecamatan Pancarijang yaitu memiliki jerami jagung dan hijauan yang dapat mendukung ketersediaan limbah tanaman pangan berdasarkan bahan kering sebagai pakan ternak ruminansia.
 
Kata kunci: Daya dukung, Hijauan, Limbah tanaman pangan, Location quotient, Produksi bahan kering
PENGGUNAAN TEPUNG MAGGOT BSF (Hermetia illucens) DALAM RANSUM TERHADAP PERFORMA PERTUMBUHAN AYAM PETELUR JANTAN
Authors: Susanto Jepri , Kaharuddin Desia , Kususiyah
Published: March 2024

Penelitian ini bertujuan untuk mengevaluasi pengunaan tepung maggot BSF (Hermetia illucens) dalam ransum terhadap performa pertumbuhan ayam petelur jantan. Penelitian menggunakan Rancangan Acak Lengkap (RAL) 4 perlakuan dengan 5 ulangan dan setiap ulangan menggunakkan 8 ekor ayam petelur jantan strain Lohmann Brown. Faktor pembeda antar perlakuan adalah level penggunaan tepung maggot dalam ransum, yaitu: 0% (P0), 4% (P1), 8% (P2), dan 12% (P3). Variabel pengamatan yaitu konsumsi ransum, bobot badan, pertambahan bobot badan dan konversi ransum. Hasil penelitian menunjukkan bahwa penggunaan tepung maggot berpengaruh nyata (P<0,05) terhadap performa pertumbuhan ayam petelur jantan. Konsumsi ransum, bobot badan dan pertambahan bobot badan P0 dan P1 nyata lebih tinggi dibandingkan P2 dan P3, sedangkan konversi ransum P0, P1, dan P2 lebih rendah dibandingkan P3. Dapat disimpulkan bahwa tepung maggot dapat digunakan sampai level 4% tanpa menurunkan konsumsi ransum, bobot badan dan pertambahan bobot badan, sedangkan efisiensi ransum menurun pada level 12%.
 
Kata kunci : Ayam Petelur Jantan, Performa Pertumbuhan, Tepung Maggot.
PERAN KELOMPOK WANITA DALAM PENGEMBANGAN PETERNAKAN KAMBING PE: KONTRIBUSI TERHADAP PENCAPAIAN SUSTAINABLE DEVELOPMENT GOALS (SDGs)
Authors: Rosa Zulfikhar  , Budi Purwo Widiarso  , Sukadi  , Wardi
Published: March 2024

Penelitian ini bertujuan untuk mengetahui pengaruh lima variabel karakteristik inovasi, antara lain keuntungan relatif, keselarasan, kerumitan, dapat dicoba, dan dapat diamati, terhadap persepsi peran wanita dalam mengembangkan peternakan kambing Peranakan Etawa (PE) serta kontribusi pencapaian sustainable development goals (SDGs). Terdiri dari kelompok Wanita tani di Desa Ngargoretno, kecamatan Salaman, kabupaten Magelang. Penentuan lokasi penelitian dilakukan secara purposive berdasarkan pertimbangan bahwa kabupaten magelang digunakan untuk pengembangan kambing PE. Metode penelitian menggunakan analisis kuantitatif deskriptif untuk mendapatkan 30 anggota kelompok tani wanita sebagai responden. Selanjutnya variabel yang diteliti adalah karakteristik inovasi dan persepsi petani yang diukur dengan model matematika menggunakan kategori skor masing-masing variabel dan program SPPS. Hasil penelitian menunjukkan bahwa persepsi petani terhadap kelima variabel tersebut termasuk dalam kategori setuju. Hal ini mendapat dukungan positif dari responden dengan melihat keuntungan penerapan paket teknologi pada pengembangan kambing PE. Ditinjau dari aspek peran wanita dalam pengembangan kambing PE dapat mengambarkan kesetaran gender dalam dunia peternakan. Selanjutnya dapat menjadi pencapaian sustainable development goals (SDGs).
 
Kata kunci: KWT Bugenvil, Persepsi, SDGs, Wanita
RACISM AS A SOCIAL ISSUE IN BLACK EYED PEAS SONG “WHERE IS THE LOVE?”
Authors: Sutrisno Bejo , Tantriana Yulan Dewi , Rachmawati Budi
Published: March 2024

This research departs from the problems that occur related to racial discrimination that occurred in America. This study aims to examine the social issue surrounding the superiority of racist violence. Finding out the types of racism exist and describing how it is portrayed in the Black Eyed Peas song “Where is The Love?” are the goals of this study. Content analysis is a type of qualitative research that was employed in this research by the researcher. Unit analysis was used to gather data from the song through words and lyrics. The themes in the data were categorized, coded, and classified. Following that, the data were interpreted using the writer's point of view. The result showed that “Where is The Love?” song contained racism in the form of prejudice, and physical violence occur in the song. The “Where is The Love?” song represents racism in America because it was based on the tragedy happened in the past where Black Americans have been treated bad by the superiority.
ТЕСТУВАННЯ ПРОГРАМНОГО ЗАБЕЗПЕЧЕННЯ У 2023 РОЦІ: НОВІ ТЕНДЕНЦІЇ ТА ПРОБЛЕМИ
Authors: HUNKO I.
Published: March 2024

У статті з’ясовано специфіку програмного забезпечення 2023 року, зокрема, розкрито особливості об’єднання адаптації та інновації, щоб задовольнити мінливе середовище розробки програмного забезпечення. У дослідженні висвітлено модерні тенденції у тестуванні програмного забезпечення (штучний інтелект і машинне навчання в автоматизації тестування, безперервне тестування та DevOps, інтеграція технології блокчейн у безпечне тестування програмного забезпечення); з’ясовано головні проблеми та ризики галузі (управління тестовими даними, питання тестового середовища й автоматизації тестування; ризики якості, надійності та безпеки, комплаєнс і регуляторні ризики). Доведено потребу нагального впровадження сучасних інновацій в українську царину тестування програмного забезпечення задля надання ефективних програмних рішень, котре охоплює всі аспекти життєдіяльності, гарантуючи надійність, безпеку і функціональність.
Cultural Synergy: Participatory Innovation in Maintaining the Sustainability of Muaro Jambi Temple
Authors: Asnia Putriya , Saha Shagnik , Wijesooriya Gayan Madhusanka
Published: March 2024

Purpose of the study: This research aims to see how the community participates in efforts to preserve the cultural heritage of Muara Jambi Temple. Methodology: The method used in the research is a qualitative method with a naturalistic qualitative type. The locations in this research are the Jambi Cultural Heritage Conservation Agency as the manager and Muara Jambi Village, Maro Sebo District, Muaro Jambi Regency, Jambi Province. Qualitative methods rely on qualitative data, which can take the form of interviews, participant observation, field notes, or document analysis. Main Findings: The results of this research show that the community already has awareness in preserving the cultural heritage of Muarajambi Temple, which can be proven by the existence of a community founded by the people of Muarajambi Village with awareness of the importance of protecting the environment around Muarajambi Village and the Muarajambi Temple environment. Several forms of community participation, in this case the participation of ideas/thoughts, are considered to be still low because they are not channeled enough. This has not been fully implemented due to a lack of coordination or approach between the community and managers. Various efforts have been made by the management and the community, including protection in the form of restoration, development and utilization of cultural heritage, which can be done through direct promotion or through social media, and Muarajambi Temple is also a scientific, religious, social and cultural institution. Novelty/Originality of this study: The synergy between local culture, participatory innovation and the character of love for one's country is a strong pillar in maintaining the sustainability of Muara Jambi Temple, proving that preserving cultural heritage is a reflection of togetherness and unity in preserving heritage for future generations.
TO THE QUESTION OF THE EFFECTIVENESS OF THE CUMULATIVE SYSTEM OF ASSESSING INDIVIDUAL ACHIEVEMENTS OF STUDENTS
Authors:   Samara State Transport University, Gumennikova Yu.V. , Zolkin A.L. ,   Povolzhskiy State University of Telecommunications and Informatics, Chernitsyna R.N.
Published: March 2024

The article describes one of the possible ways to solve the most important problem of modern higher education in Russia – the low motivation of students to acquire the knowledge, skills and abilities they need in their future professional activities. According to the author, the implementation of a cumulative system for evaluating individual achievements of students in the educational process can contribute to the solution of this problem. Such an assessment system makes it possible to transform the student's desire to get a high grade into an awareness of the need for conscientious and systematic work throughout the semester, increases the objectivity of the teacher's assessment, improves the quality of training and the level of formation of professional competencies. The paper provides a conditional example of the distribution of points of the current and final control in one semester of studying mathematics by students of construction specialties at the Samara State University of Railways. To identify the students' opinion on the effectiveness of the applied cumulative assessment system, the author developed a questionnaire. The survey was conducted anonymously, 243 people took part in it. The analysis of its results suggests that the majority of respondents (about 70%) recognize the effectiveness of the cumulative evaluation system described in the work.
DIGITAL DIAGNOSTICS OF PARAFUNCTIONAL DISORDERS OF THE MASTICATORY MUSCLES WITH INCREASED TOOTH ABRASION
Authors:   Samara State Medical University, Tlustenko V.S.
Published: March 2024

In the domestic and foreign literature, studies are published on the relationship of a decrease in interalveolar height due to increased tooth abrasion with disorders of chewing muscles (bruxism). The main signs of bruxism are clenching and gnashing of teeth. However, along with their general properties, there is no information about their difference in the state of muscle tone, which was the purpose of the study. The processes were modeled and a comparative assessment of the state of muscle tone in these symptoms was carried out on the basis of a digital research method–electromyography. 2 groups were formed for the analysis: the main (I and II subgroups) and the control. Subgroup I included patients with the main symptom of "clenching teeth", and subgroup II included patients with "gnashing teeth". The results showed higher average values of the amplitude of biopotentials in the masticatory and temporal muscles in subgroup I compared with subgroup II. Digital diagnostics by the EMG method made it possible to establish the presence of parafunctional disorders of the masticatory muscles.
THE HISTORICAL SIGNIFICANCE OF THE SONG “DJURJEVDAN”: ON THE PROBLEM OF SELECTION OF MUSICAL MATERIAL FOR STUDIES
Authors:   Russian State Institute of Performing Arts, Vucenovic A.
Published: March 2024

The author touches upon the issue of justification and logic of musical material (folk and/or original) used in the process of directing performances or student sketches. This aspect is emphasized in the context of the problem of upbringing and education of future directors and actors. Emphasis is placed on the need for a more careful selection of any, including world-famous, musical material in order to avoid harmful mistakes when preparing performances. Freedom of creativity does not give theater workers the right to distort history. In this article, the object of study was the song “Djurdjevdan”, the historical roots of which, according to one version, go back to the “death trains” during the Second World War, the Serbian genocide, but which is now interpreted as a song about love conflicts, out of ignorance it is performed in the territory of the former Yugoslavia “both at weddings and funerals.” The song “Djurdjevdan” became popular in Yugoslavia in 1942 after it was sung by one of the Bosnian Serbs transported to the Jasenovac concentration camp. Then other, no less tragic events from the history of Serbia were layered. The song became world famous thanks to the film by E. Kusturica “House for Hanging” (“Time of the Gypsies”), in which the key scene is the celebration of St. George’s Day (St. George’s Day), Djurdjevdan in Serbian or, in the language of the Gypsies, Ederlezi.
DOMESTIC MUSIC PUBLISHING BUSINESS OF THE SECOND HALF OF THE XIX – EARLY XX CENTURIES: CHARACTERISTICS AND FEATURES OF THE FUNCTIONING OF THE INDUSTRY
Authors:   Russian State University named after A.N. Kosygin, Radzetskaya O.V.
Published: March 2024

The article is devoted to the peculiarities of the development of the domestic music publishing business in the second half of the XIX – early XX centuries, the structure, organization and functioning of trade activities of large and small enterprises. Strategically important positions that create a holistic view of the mechanisms of obtaining material profit, effective ways of enlarging and optimizing printing production are identified, the system-forming factors influencing the process of individualization of its corporate identity are indicated. These include: foreign entrepreneurs who headed a number of the largest Russian firms; commercial strategies aimed at monopolizing the market and strengthening its dynamics. An important addition to this context are: the presence or absence of its own music printing, the production and sale of musical instruments, accessories and related products, as well as the experience of patronage and charity, which has no analogues in world practice, allowing us to talk about the exceptional cultural status and phenomenon of domestic music publishing. The work of well-known trademarks after 1917 in Soviet Russia and abroad becomes a great information resource of the declared topic. The totality of the results obtained creates an idea of the various facets of this phenomenon in the space-time dynamics and perspective and forms additional opportunities for its study
Design and application of agricultural guarantee digital system platform Design and application of agricultural guarantee digital system platform
Authors: zhang caiming , wen xiaoyi , pan taiping , yang sheng , tang bicheng
Published: March 2024

It is obvious that the modern agriculture needs the support of modern finance. The agricultural credit guarantee system, is an important means to promote the financial capital into the agriculture industry, and to solve its financing difficulties and its high cost. The designing and application of agricultural guarantee digital system platform will not only be beneficial to accelerate transformation and promotion of the mode of agricultural development, but also be positive significance on the steady growth, promoting the reform, restructuring and livelihood. This paper summarizes the relevant literatures on agricultural guarantee system, designs and develops a set of agricultural guarantee digital system platform based on the application of blockchain and big data technology, and finds it achieves a lot of benefits and good effects based on the practice in China.
Changes in the IR Spectra of Energy Metabolism Metabolites in the Blood of Rats with Hepatocellular Carcinoma Under the Influence of Hyperthermia and Apitoxin
Authors:   Privolzhsky Research Medical University, Krasnikova Ol’ga V. , Kondrashina Ol’ga V. , Piskunova Marina S. , Kondrat’eva Anastasiya R. , Kol’tyukova Natal’ya V. , Moskovtseva Ol’ga M. , Shabalin Mikhail A. ,   National Research Lobachevsky State University of Nizhny Novgorod
Published: March 2024

There is a need to develop and improve conservative treatment methods for malignant liver tumours, since only in a small percentage of cases (10–30 %) radical treatments can be applied. Therefore, of relevance are studies into the effect of hyperthermia on the absorption of antitumour drugs and the effect of bee venom as a physiological therapeutic agent on the energy metabolism of tumour cells. Infrared spectroscopy could potentially be used to study changes in energy metabolism parameters in the blood plasma. The purpose of this article is to assess changes in the concentrations of energy metabolism metabolites in the blood of tumour-bearing animals during hyperthermia under the action of apitoxin using infrared spectroscopy. Materials and methods. The research involved 50 white non-linear female rats, divided into an intact, control and three experimental groups. The control and experimental groups were inoculated with hepatocellular carcinoma. The experimental groups were injected intraperitoneally with honey bee venom followed by hyperthermia sessions at different temperatures (42.5; 43.5 and 44.5 °С). Blood plasma was studied using a spectrophotometer in the wavenumber range of 1170–1025 cm–1. Results. We found a statistically significant increase in adenosine triphosphate concentrations (by 54 %) and a decrease in adenosine monophosphate (by 54 %), adenosine diphosphate (by 18 %) and glucose (by 87 %) levels compared to the control at 42.5 °C hyperthermia under the action of bee venom by the 7th day; however, on the 28th day the opposite effect was observed: an increase in adenosine monophosphate, adenosine diphosphate and glucose concentrations and a decrease in adenosine triphosphate levels. No positive dynamic was detected at other hyperthermia regimens. It is concluded that infrared spectroscopy can be used to assess energy changes in animals with hepatocellular carcinoma at different hyperthermia regimens under the therapeutic effect of bee venom. The optimal conditions for bee venom effects on the body are achieved at 42.5 °C.
Trends in Mortality from External Causes in the Population of the European North of Russia for 2010–2021
Authors:   Northern State Medical University, Semerikova Dar’ya A. , Solomatina Elizaveta V. , Sannikov Anatoliy L. , Grishchenkova Evgeniya V.
Published: March 2024

The purpose of this research was to assess the status and identify the specific features of population mortality from external causes in the Arkhangelsk Region, Nenets Autonomous Area and Komi Republic for the period of 2010–2021. Materials and methods. Information about external cause mortality in the above regions for the period under study was obtained from the statistical monitoring databases of the Russian Federation – Unified Interdepartmental Statistical Information System – as well as from the official websites of the Main Directorate for Traffic Safety of the Ministry of Internal Affairs of Russia, and Federal State Statistics Service. Mathematicalstatistical and information-analytical methods were used in the paper. Results. In 2010–2021, the Arkhangelsk Region saw a steady downward trend in road traffic mortality; however, its average mortality rates remained at a higher level compared to the Nenets Autonomous Area and Komi Republic. During the period under study, the highest suicide rate among the regions was observed in the Nenets Autonomous Area: an average of 44 cases per 100,000 population annually, while in the Komi Republic and Arkhangelsk Region it was 30 % lower, i.e., 30.8 and 30.7 cases per 100,000 population, respectively. A better situation was observed in terms of homicide mortality, which decreased significantly between 2010 and 2021 in the regions under study. During the same period, mortality rates due to accidental alcohol poisoning dropped in all three regions; however, the average rate remained higher than the national average: 23.8, 12.2 and 26.1 cases per 100,000 population in the Arkhangelsk Region, Nenets Autonomous Area and Komi Republic, respectively. Dynamics of mortality from occupational injuries over the 12 years in the regions under study is insignificant and overall is similar to the national dynamics.