bluuebunny/crossref_metadata_2025 huggingface dataset:
Application of the finite element analysis in the development of new dental implant systems. Literature review
Authors: Sergeev Yu. A. , Dolgalev A. A. , Choniashvili D. Z. , Avanisyan V. M.
Published: March 2023

Introduction. The development of new dental implants in the context of the booming domestic industry makes it possible to find alternative options in the treatment of clinically difficult situations, to select the necessary individual solution during dental implant surgery, and consequently, to perform the surgery in an error-free manner and achieve the desired results. The development of a dental implant is a multistep process, and the characteristics of the implant material and its biophysical characteristics must be studied in detail until the implant is integrated into the bone tissue.   The aim of the study: to estimate the opportunities and prospects of applying the finite elements method by developing the new systems of dental implants according to the literature data.   Material and methods. A search was carried out in the national digital libraries e-library, CyberLeninka, as well as PubMed, Medline, Web of Science and Google Scholar using the following keywords: dental implant, finite-element analysis, mathematical model. Sixty-nine papers were selected and analysed.   Results. The finite element method is an accurate method to analyse the implant being developed, but it has certain limits, because in the finite element mesh, the implant-bone interface is a continuous relationship. The absence of micro-movement at the implant-bone interface during loading is different from the actual clinical situation. The expected 100 % osseointegration based on 3D-modelling can’t be an ideal option and never corresponds to the reality in the clinical situation. However, the use of the finite element method makes it possible to test single loads and inclination angles, which in the clinical situation is very rare.
Assessment of the level of oral hygiene and the condition of the hard tissues of the teeth in ballet dancers of different age groups
Authors: Timoshina M. D. , Sevbitov A. V. , Borisov V. V. , Zaborskaya P. A. , Zangieva O. T.
Published: March 2023

The profession of ballet dancers is always associated with excessive physical exertion, which in turn leads to increased muscle tension in all parts of the body, including the muscles of the facial skeleton. This, in turn, can lead to injuries and increased abrasion of the hard tissues of the teeth and, as a result, to various occlusive disorders. Against the background of an excessively busy training schedule, a ballet dancer may lack time for oral hygiene. All of the above can affect the level of oral hygiene and the condition of the hard tissues of the teeth.   The purpose of the study is to improve the efficiency and quality of dental care for ballet dancers of various age groups based on the identified features of oral hygiene and the condition of hard dental tissues and the need for dental treatment.

   Materials and methods: 75 ballet dancers were assessed for oral hygiene OHI-S and tooth erasability, determination of the area of occlusal contacts and registration of supracontacts.   Results and conclusions: the age and work experience of a ballet dancer directly affects the level of oral hygiene and the condition of the hard tissues of the teeth. Ballet dancers have average satisfactory and high unsatisfactory indicators of the level of oral hygiene, as well as increased tooth abrasion and occlusive disorders of varying severity.
The effect of anodic dissolution of various types of electrodes on the antibacterial effect during transcanal endodontic direct current exposure
Authors: Tsarev A. V. , Dikopova N. Zh. , Ippolitov E. V. , Volkov A. G. , Razumova S. N. , Podporin M. S. , Brago A. S.
Published: March 2023

The aim of the work was to study the antioxidant efficiency of anodic dissolution of silver-copper and copper electrodes, cases of near-canal endodontic effects in Tocom disease, in relation to mixed cultural transgenic pathogens infected with root diseases when examining chronic forms of pulpitis.   The results of the study showed that the anodic dissolution of both silver-copper and copper electrodes has a pronounced and, in general, unidirectional antibacterial effect. It was found that the anodic dissolution of the copper electrode showed a more pronounced effect on mixed cultures of pathogenic microorganisms S. constellatus + F. nucleatum and Streptococcus sanguis + Enterococcus faecium. The data obtained indicate that in apex-phoresis in teeth with partially obliterated root canals, along with anodic dissolution of silver-copper electrodes, anodic dissolution of copper electrodes can be used.
Methods for diagnosing neuropathy of the inferior alveolar nerve
Authors: Kocharyan A. M. , Amkhadova M. A. , Ivanova E. V. , Delokian G. A. , Antonov D. A.
Published: March 2023

Neuropathy of the inferior alveolar nerve (IAN) is one of the urgent problems of dentistry and neurology. The article is devoted to the issues of early and late diagnosis of neuropathy IAN by clinical, radiological and functional diagnostic methods. Evaluating the study of 22 patients over the course of a year, we came to the conclusion that early diagnosis is the most informative and qualitative. In this regard, the development of a diagnostic technique for neuropathy IAN will reduce the time and improve the quality of treatment, as well as significantly reduce the consequences of complications.
Development and justification of a hardware and software complex for the diagnosis of diseases of the oral mucosa
Authors: Shkarin V. V. , Makedonova Yu. A. , Dyachenko S. V. , Venskel I. V. , Gavrikova L. M. , Devyatchenko L. A.
Published: March 2023

Relevance. Currently, a significant increase in diseases of the oral mucosa, manifested by inflammatory and destructive lesions, has been revealed. To determine the correct tactics for the treatment of inflammatory and destructive lesions in lichen planus, it is necessary to comprehensively assess the situation in the oral cavity, taking into account planimetry data, the size of the inflammatory background, the presence of exudate, the severity of pain syndrome, and also include criteria for the stages of the lesion in the evaluation system, which requires a personalized and differentiated approach to patient management tactics.

   The purpose of this work was to develop and substantiate a hardware and software complex for the diagnosis of diseases of the oral mucosa.

   Materials and methods. The study involved 34 patients with erosive and ulcerative form of lichen planus. The patients were diagnosed with pathological elements of the oral mucosa using the developed hardware and soft-ware complex. Pain was determined (in points), the area of inflammation, the area of fibrinous plaque, the total area of the lesion for 14 days. Assessment of the stages of the pathological process contributed to the differentiated appointment of pharmaceuticals. According to the results of the clinical examination, the effectiveness of the hardware and software complex for the diagnosis of diseases of the oral mucosa has been proved and justified.

   Conclusion. During the study, it was reliably proved that the use of a hardware and software complex is advisable to include in the algorithm of examination of patients with diseases of the oral mucosa. No side effects and complications were detected. When drawing up a treatment plan, it is necessary to approach each patient individually, depending on the clinical situation.
Evaluation of the effectiveness of treatment and monitoring of patients with systemic bone tissue disorders during dental implantation
Authors: Agazade A. R. , Agazade R. R. , Gergieva T. F. , Amkhadov I. S. , Kadiev A. А. , Mammadov S. E. , Zeynalov J. I.
Published: March 2023

The article presents a study of bone mineral density by DEXA and evaluated the effectiveness of correcting therapy using vitamin D by quantitative ultrasound densitometry to increase the effectiveness of the treatment of patients with dental defects in the background of systemic osteoporosis by dental implantation.   Materials and methods: 619 people were examined by quantitative ultrasonic densitometry. The dynamics of changes in bone mineralization was studied with an interval of six months and 1 year. A comparative analysis of the average values of quantitative ultrasonic densitometry was carried out at various times after the installation of dental implants in the control and main groups.   Results. Sound velocity values in patients with normal bone mass were (4203,3 ± 7,9). In patients with osteopenia, the rate of ultrasound in bone tissue was 3992,2 ± 3,6 (p < 0.001); in patients with osteoporosis 3802,7 ± 14,9 (p < 0.001). All these parameters were obtained after the use of corrective therapy with vitamin D3.   Conclusions. The analysis of the results of quantitative ultrasound densitometry revealed that in the group of patients with osteoporosis, the indicators were reduced by an average of 9.5 % compared with patients with normal bone indicators (p < 0.001).
Topographic and anatomical substantiation of the use of vascularized flaps for plastic reconstruction of soft tissues of the alveolar ridge
Authors: Kononenko V. I. , Sumkina O. B. , Domenyuk D. A. , Kochkonyan T. S. , Sletova V. A. , Magomedova Kh. M. , Dmitrienko D. S. , Domenyuk S. D. , Sletov A. A.
Published: March 2023

Promising scientific research in modern dentistry and maxillofacial surgery is focused on solving the issues of long-term and stable results of implant treatment in the rehabilitation of patients with partial or complete absence of teeth in conditions of deficiency of the soft tissue component of the alveolar ridge. Clinicians have proposed a variety of plastic surgery techniques, in which soft tissue defects are simultaneously replaced with a vascularized flap, a revascularized autograft, or by stage-by-stage replacement of a defect with a pedunculated flap, followed by its cut-ting off and modeling, taking into account the individual characteristics of the formed area. The long-term clinical success of dental implantation is largely determined by the functional state and reactive properties of the soft tissues surrounding the implant, which play an important role not only in achieving a highly aesthetic result, but also in preventing complications of implant treatment. The use of an operative multi-stage method for reconstructing the soft tissue component of the alveolar ridge with a mu-coperiosteal vascularized flap from the bone palate, developed on animal biological dummies (pigs), allows you to pre-plan the volume of surgical intervention, as well as the shape of the donor and recipient zones. Topographic and anatomical substantia-tion of the optimal modeling of the mucoperiosteal flap from the bone palate will al-low avoiding excessive donor tissue sampling, minimizing the invasiveness and trauma of surgical intervention, forming a soft tissue buffer zone of the required vol-ume to prevent bone resorption in the peri-implant area, increase the service life of dental implants, increase the reliability of prosthetic designs and long-term operation.
Experimental modeling of various osteotomy modes during navigation trepan biopsy of the jaws
Authors: Abraamyan L. K. , Tsitsiashvili A. M. , Volkov A. V. , Lezhnev D. A. , Panin A. M.
Published: March 2023

In surgical dentistry, the sampling of the biomaterial of the jaws is usually carried out with the help of dental trepans. As a result of osteotomy, a friction force inevitably arises during trepan biopsy, which can lead to local hyperthermia and, as a consequence, coagulation necrosis of both the bone tissue of the jaw itself and damage to the resulting biopsy. Local overheating can lead to complicated healing of a bone wound in the area of a trepan biopsy, lead to difficulties in verifying the morphological picture of the disease and, as a consequence, further treatment of the patient. When conducting a navigational trepan biopsy using a surgical template, the risk of hyperthermic exposure increases, and the question of choosing the rotation speed becomes obvious. The literature presents limited data on osteotomy regimes using a trepan cutter during jaw bone biopsy, including using a navigational surgical template, which determined the relevance of the study.   The purpose of the study: to determine the permissible speed of rotation of the trepan cutter during the navigation trepan biopsy of the jaw bones.   Materials and methods: 20 (5) micro-preparations were made from trepan biopsies of the femur of cattle, obtained at speeds of 800 rpm, 500 rpm, 250 rpm, 50 rpm in the classical way; 15 (5) micro-preparations were also made from trepan biopsies obtained at speeds of 350 rpm, 200 rpm, 50 rpm using a surgical navigation template. The width of pathological changes in the tectorial properties of ostein due to coagulation damage of the bone matrix in microns was measured using SlideViewer (3DHISTECH), a built-in tool for measuring linear parameters in microns. The statistical significance of the obtained values was determined using the Kraskel – Wallis H-test.   Results: with osteotomy at a speed of 50 rpm, the width of the bone matrix damage reached up to 10 microns. As the rotation speed increased, the width of the damage also increased: at 200 rpm – Me = 36.8 microns, 350 rpm – Me = 98.6 microns.   Conclusion: when conducting a navigational trepan biopsy using a surgical template, the recommended rotation speed of the instrument is up to 350 rpm.
Characteristics of speech function in the process of patients getting used to removable dentures
Authors: Kerimkhanov K. A. , Iordanishvili A. K.
Published: March 2023

Relevance. The majority of elderly and senile patients in the Russian Federation still use removable acrylic dentures, which is associated with the economic problems of the elderly. However, there are few studies devoted to the study of the effect of such dentures on the quality of speech function.   Objective. Evaluation of quality of speech function in the patients with partial and complete tooth loss during the adaptation to the removable dentures including using by patients new home-made adhesive cream for denture fixation.   Materials and methods. Overall 111 (33 male and 78 female) elderly patients with partial (63) and complete (48) tooth loss were examined and were divided into 4 study groups. Groups 1 and 2 included patients with partial tooth loss and groups 3 and 4 included patients with total tooth loss. There were also examined 17 elderly people who had no defects of dentition and formed a control group. The defects of dental rows in the patients of groups 1–4 were eliminated by making removable dentures. At the same time, during the adaptation period, patients in groups 2 and 4 of the study used a new domestic adhesive cream for fixing dentures. Before treatment and during the adaptation period, the quality of speech function of the patients was studied.   Results. It was found that with preservation of the integrity of the dental rows in the elderly people a high quality of speech is observed. Loss of teeth leads to a decrease in the quality of speech function, especially in patients with partial loss of teeth in the anterior part of the jaw or front teeth on both jaws. By the middle of the adaptation period, the quality of speech function had improved in all patients examined, both with partial and total tooth loss. Use of the adhesive cream by patients provided a reliably better quality of speech function with partial and full removable acrylic dentures, which was characterised as «high» at the end of the adaptation period.   Conclusion. On the basis of the conducted research, home-made adhesive cream for denture fixation can be recommended to patients with the purpose of optimization of the adaptation period to removable acrylic dentures as well as for permanent use, which will improve not only fixation and stabilization of dentures, state of the prosthetic bed mucosa, but also the quality of speech function.
ERGENLİK ÖNCESİ TENİS OYUNCULARI VE SEDANTERLERİN ANTROPOMETRİK ÖZELLİKLERİNİN VE BAZI PERFORMANS PARAMETRELERİNİN KARŞILAŞTIRILMASI
Authors: BİNGÖL DIEDHIOU Azize , ANDRE Hülya , AKÇA Fırat
Published: March 2023

Bu çalışma, 10-12 yaş aralığında, tenis oynayan ve sedanter kız ve erkek pre-adölesanların antropometrik ve somatotip özellikleri ile patlayıcı güç ve çeviklik özelliklerinin incelenmesini amaçlamaktadır. Katılımcılar cinsiyetlere göre ayrılmış; deney grubu (DG) ve kontrol grubu (KG) olmak üzere iki grup oluşturulmuştur. Katılımcıların vücut ağırlığı (VA), vücut kitle indeksi (VKİ), vücut yağ yüzdesi (VYY), somatotip karakteristikleri belirlenmiştir. Daha sonra çeviklik testi ve patlayıcı gücü değerlendirmek için durarak uzun atlama testi uygulanmıştır. İstatistiksel analizler SPSS yazılım versiyonu 22.0 ile yapılmıştır. Katılımcıların tanımlayıcı istatistikleri belirlendikten sonra verilerin normal dağılım gösterip göstermediği Shapiro-Wilk testi ile değerlendirilmiştir. Veriler normal dağılım gösterdiği belirlendikten sonra bağımsız örneklemler için t-testi uygulanmıştır. Her bağımlı değişken için etki büyüklükleri (Cohen's d) hesaplanmıştır. İstatistiksel anlamlılık değeri p<0.05 olarak kabul edilmiştir. Elde edilen veriler değerlendirildiğinde kız ve erkek DG ve KG arasında boy, VA, VKİ, VYY değerlerinde istatiksel olarak anlamlı fark saptanmamıştır (p>.05). Somatotip özellikler değerlendirildiğinde, kız ve erkek DG ve KG arasında istatiksel olarak anlamlı fark görülmemiştir (p>.05). Performans testleri incelendiğinde ise durarak uzun atlama testinde kız pre-adölesanlarda gruplar arasında istatiksel olarak anlamlı fark saptanmazken (p>.05), erkek pre-adölesanlarda gruplar arasında DG lehine istatiksel olarak anlamlı fark saptanmıştır (pK=.589; pE=.012). Çeviklik testinde ise hem kız hem de erkek pre-adölesanlarda DG lehine istatiksel olarak anlamlı fark görülmüştür (pK=.000; pE=.000). Bu çalışmanın sonucunda; kız ve erkek DG ve KG arasında antropometrik ve somatotip özellikler açısından fark görülmediği gözlenmiştir (p>.05). Bununla birlikte DG erkeklerin patlayıcı güç ve çeviklik özelliklerinin KG’a kıyasla daha iyi olduğu görülmüştür. Katılımcı kızlarda ise çeviklik özelliğinin DG’da KG’a kıyasla daha iyi olduğu görülmüştür (p<.05).
Data-to-Deal (D2D): Open Data and Modelling of Long Term Strategies to Financial Resource Mobilization - the case of Costa Rica
Authors: Jaramillo Marcella , Quirs-Torts Jairo , Vogt-Schilb Adrien , Money Alex , Howells Mark
Published: March 2023

Long Term Scenarios (LTSs) can be developed through an iterative process of codesigning with stakeholders and experts to form a joint vision of a development path. Once a roadmap is defined, governments can match financing sources and instruments to deliver the measures and projects defined in the LTS, providing signals to align broader finance flows toward the lower carbon economy. The exercise can increase access to and effectiveness of international climate finance. In the case of Costa Rica, a data-driven, stakeholder-codesigned National Decarbonization Plan (the country's LTS) was launched in 2019. It has been the foundation on which at least US$2.4 billion had been mobilized from international concessional finance sources by the end of 2022. An essential effort underpinning this was a carefully crafted and nationally owned LTS study that leveraged public-good open-models and associated: advanced-schools, communities, principles, and goals. The LTS study's direct cost was less than US$200k.
The Trope of House: A Study of Freudian Uncanny in Guy de Maupassant’s “The Horla”
Authors: Ghosh Sourav
Published: March 2023

In literature and cultural studies, the idea of the home as a location for the strange has frequently appeared. The home as a familiar space can be interpreted as strangely familiar with uncanny manifestation. Familiar rooms suddenly feel foreign, and the line between the inside and outside could become hazy. Home in Guy de Maupassant's “The Horla”, acts as an active entity to create horror— initially a space of comfort. Also, the house serves as a symbol of the character's psychological state, and the uncanny elements within the house reflect anxieties. While the Horla (or the out there) is invariably read by scholars as the double, the projection in “The Horla” emphasizes the idea that the home can be both reassuring and unsettling, familiar yet strange. My paper examines how the house creates the trope of horror, which leads to the narrator’s burning down the house and also committing suicide.
Unmet Health Needs During the COVID-19 Pandemic
Authors: YALÇIN IRMAK Aylin , OZTURK EYİMAYA Aslıhan
Published: March 2023

Objective: This study aimed to identify the unmet health needs of adults during the COVID-19 pandemic, the reasons for these needs, solutions sought and socio-demographic determinants.

Methods: The cross-sectional online survey was conducted with 2,074 adult individuals from December 15 to December 31, 2020. Data were collected using Socio-demographic Data Collection Form, Unmet Health Needs Data Collection Form and World Health Organization Quality of Life Scale (WHOQOL).

Results: The percentage of the participants who stated that they had unmet health needs was 66% and the most unmet needs reported were oral and dental treatment (46.3%), eye health and treatment for vision disorders (22.5%), and early diagnosis and annual health screening (11.4%). The reasons with the most impact on the emergence of these needs were fear of being infected with the virus (44.3%), lack of access to health care (42.7%) and not wanting to cause a burden on the health system. There was a significant difference between the groups with and without unmet health needs in terms of gender, economic status, presence of health insurance, presence of chronic disease, perception of health, and WHOQOL total scores.

Conclusion: The findings obtained will benefit policymakers in the rational use of limited resources and making strategic arrangements for needs.
The Effects of Fulvic Acid Against Water Avoidance Stress-Induced Damage of Rat Colon Mucosa
Authors: ÇİKLER Esra , SÖĞÜT İbrahim , AYDOĞAN Sezen Gizem , KIRMIZIKAN Seda , HÜRDAĞ Canan
Published: March 2023

Objective: Chronic stress plays an important role in the etiology of many inflammatory diseases. Reactive oxygen species (ROS), a source of free radicals, act as signaling molecules in the progression of stress-related inflammatory diseases. Oxidative stress occurs as a result of an increase in free radicals in the tissues. The damage caused by oxidative stress can be reduced by antioxidant replacement. In our study, the effect of fulvic acid, a powerful antioxidant, on the damage caused by the water avoidance stress model in the rat colon was investigated morphologically and biochemically.

Methods: Experimental groups (n=6, Sprague-Dawley male rats, 300 g): control (C), water avoidance stress (WAS), and water avoidance stress+fulvic acid (WAS+FA). Rats in the WAS + FA group were given a single dose of FA (150 mg/kg i.p.) immediately after exposure to water avoidance stress. The colons were stained with hematoxylin-eosin and toluidine blue. Total antioxidant status (TAS), total oxidant status (TOS), and oxidative stress index (OSI) were analyzed biochemically.

Results: Compared to the C group, the WAS group showed epithelial damage, a few empty goblet cells, inflammatory cell infiltration, and many active mast cells in the connective tissue. Mucosal integrity, the number of goblet cells, and mast cell activity improved in the WAS+FA group as compared to the WAS group. Biochemically, as compared to the C group, TAS levels decreased, and TOS and OSI levels increased in the WAS group. In the WAS+FA group, TAS levels increased, and TOS and OSI levels decreased with respect to those in the WAS group.

Conclusion: Our findings indicated that fulvic acid reduced the damage caused by chronic oxidative stress in the colon.
Oral and Dental Health Knowledge and Attitudes among Parents of Children
Authors: KÖSE Hazal Deniz , ŞEN YAVUZ Betül , KARGUL Betul
Published: March 2023

Objective: This study aims to evaluate parents’ knowledge and attitudes level on oral and dental health.

Methods: One hundred and thirty parents of children aged 6-12 years, were invited to participate in the study. A 33-item questionnaire covering socio-demographic characteristics, dental attitude, dietary practices, tooth eruption, dental caries, and oral hygiene practices, was distributed to parents. The relationship between categorical variables was tested with the Chi-square test.

Results: The sample comprised of 100 parents with a mean age of 37.1 ± 6.4. The knowledge and attitudes towards dental caries and oral health habits among parents did not differ significantly according to the parents’ gender, education level, or dental chair experience. There was a statistically significant difference in the responses of the first primary tooth and the first exfoliating primary tooth according to the gender of the parents (p=0.031, p=0.002, respectively). Although the education level of the parents did not affect the answers about the number of primary and permanent teeth, a statistically significant difference was found in the time of first primary tooth eruption (p=0.008).

Conclusion: The study showed that parents do not have enough knowledge and awareness of dental caries and oral healthcare. Oral healthcare should be promoted as a part of general health and the awareness of the public should be increased.
The Effects of Office Bleaching Techniques on Nanoceramic Composite Resin
Authors: ÜLPER Esin , TÜRKMEN Cafer , CİMİLLİ Hale
Published: March 2023

Objective: The aim was to evaluate the effect of activated bleaching agents on the nanoceramic composite resins based on microhardness and surface roughness measurements. Methods: Opalescence Boost (Ultradent Products, USA) and Whiteness HP Blue Calcium (FGM Dental Products, Brazil) bleaching agents and a nanoceramic composite resin Ceram.X® SphereTEC™ One (DENTSPLY, Germany) were used in the study. Fifty composite samples in disc form (8x2mm) were prepared. The samples were polished with discs (Sof-Lex, 3M Dental Products, St.Paul, USA) and incubated in the dark in distilled water. Samples were divided into 5 main groups (n=10). Control group (C), Opalescence Boost/ without light (OB), Opalescence Boost/ with light (OBL), Whiteness HP Blue/ without light (WB), and Whiteness HP Blue/ with light (WBL). Surface roughness (Ra) and Vickers microhardness (VHN) measurements were conducted after the bleaching process. Statistical analyses were performed using the Kruskal Wallis – H test and the Mann Whitney – U test; a p value of < 0.05 was considered statistically significant. Result: The VHN was significantly different among groups in terms of the application of bleaching agents and light (p = 0.008). The Ra was not significantly different among groups with respect to the application of bleaching agents or lighting conditions (p = 0.144). Conclusion: Within the conditions of this study, after bleaching procedure the microhardness values of the nanoceramic composite increased, however bleaching did not show any effect on surface roughness.
Investigation of the Radiological Status of Permanent First Molars in a Turkish Subpopulation
Authors: ALTINDAĞ Ali , YÜCE Fatma , MAĞAT Güldane
Published: March 2023

Objective: Missing or filled first permanent molars (FPMs) affects occlusal status and oral health. This study aims to determine the prevalence of missing, restored FPMs (filling, root canal treatment, prosthetic restoration), and dental implants in the first molar region.

Methods: In our study, panoramic radiographs of 1765 female and 1230 male patients were evaluated. Patients were divided into three age groups: 15-34 years old, 35-54 years old, and >55 years old. The maxillary and mandibular FPMs status is divided into two groups presence (caries, filled, root treatment, prosthetic restoration, root treatment + prosthetic restoration, and healthy) or absence (empty, radix relicta, dental implant, and dental bridge).

Results: In the evaluated images, 36.92% of maxillary FPMs and 27.39% of mandibular FPMs were healthy. FPMs on the right or left side of the jaws did not affect their clinical status, while their presence on the lower or upper jaw affected their clinical status.

Conclusion: Most of the FPMs (67.85%) were with caries or restorations. The number of healthy FPMs decreases with increasing age. The study indicates an important result regarding protecting FPMs and preventive dentistry.
Knowledge and Attitudes of Pregnant Women with and without Children about Fluoride and Herbal Toothpastes
Authors: ÇELİK Zeynep Ceren , ELBEK ÇUBUKÇU Çiğdem , ÇELİK Halil , DİNÇ ATA Gül
Published: March 2023

Objective: Objective: Pregnant women may be vulnerable to dental caries due to their inability to fully implement oral hygiene practices. Toothpastes are main component of oral hygiene and the most important tool for the primary prevention of caries. The study aimed to examine the knowledge and attitudes of pregnant women with children (PC) and without children (PNC) about fluoride and herbal toothpastes. Methods: A self-administered and validated 20-item questionnaire was completed by a total of 219 pregnant participants, 85 PC and 134 PNC. Statistical analyses were performed using the SciPy v1.2.3. program. Results: Most of the PC (57.65%; 69.41%) and PNC (72.39%; 47.76%) participants responded with “no idea” when asked about fluoride sources and the optimal amount of fluoride added to tap water by local health authorities (p= .006). The majority of the PC (62.4%) and the PNC (47.0%) had no preference for herbal toothpastes during pregnancy (p= .03). In addition, 86.6% of the PNC showed low knowledge about the nonfluoride content of herbal toothpastes (p= .023). While 51.5% of the PNC responded with “no idea” about a preference for herbal toothpastes for their children, 56.47% of the PC stated that they might not prefer using herbal toothpastes for their children’s routine oral hygiene. Conclusion: The findings show that both PC and PNC participants had little knowledge of toothpastes and their contents. Considering that toothpastes are the most common self-applied oral hygiene tools, knowledge and awareness of fluoride and herbal toothpastes should be raised via antenatal programs.
Effects of Scorzonera cinerea on Immune System and Hematological Parameters in Short-Term Hyperglycemia
Authors: TEMİZ Mehmet Ali
Published: March 2023

Objective: Objective: Medicinal herbs offer natural remedies for various ailments because of their comprehensive effects. Scorzonera cinerea L. (Sc) is an edible wild plant and is used in traditional medicine against various diseases. The purpose of this study was to investigate the immune system effects of S. cinerea radical leaf extract in diabetic rats.

Methods: The 5 groups were formed — Control, Diabetic, Sc-Dried, Sc-Frozen, and Acarbose. Adenosine deaminase (ADA), xanthine oxidase (XO), and myeloperoxidase (MPO) activities in liver and kidney tissues were analyzed. Hematological parameters were also evaluated.

Results: ADA, XO, and MPO activities in both tissues significantly increased in diabetic conditions. However, Sc treatments significantly decreased liver ADA, liver and kidney XO, and liver and kidney MPO activities. There was no significant change in red blood cell (RBC) parameters. Although platelet (PLT) count and MPV were raised in the diabetic group, these parameters were reduced with Sc-Dried and Sc-Frozen treatment. While lymphocyte (LYM%) significantly decreased in defense cells in the diabetic group, neutrophil (NEU%), monocyte (MO%), and eosinophil (EOS%) elevated. However, a significant decrease was observed in NEU% and EOS% with Sc treatment.

Conclusion: S. cinerea treatment can exert a potential immunoregulatory effect in diabetes. Thus, S. cinerea can be considered as an adjuvant to augment immune system on diabetes.
Determination of the Effect of the Fowler and Prone Position on Oxygen Saturation in Patients Diagnosed with COVID-19
Authors: İŞLER IŞILDAK Yeşim , ETİ ASLAN Fatma , PARLAK Goknur
Published: March 2023

Objective: This study was conducted to investigate the effect of the Fowler position and prone position on oxygen saturation in patients receiving treatment in clinics with the diagnosis of COVID-19 disease.

Method: A total of 40 patients, admitted to the pandemic ward who met the inclusion criteria, were included in the quasi-experimental type study without any sampling. The patients were first given the Fowler position and then the prone position. There was a time interval of 15 minutes wait between the two positions. For each position, peripheral oxygen saturation, heart rate, respiratory and blood pressure values were obtained at initial position placement, after the 30th minute and every hour for the first four hours.

Results: The mean age of the participants was 57.57±12.64 years. Respiratory distress, cough, fever, weakness, sweating and headache were the main symptoms. A total of 22.5% of them had a diagnosis of hypertension and Diabetes Mellitus. The requirement for the positioning was found to be 95% in the first five days after admittance. After treatment, 85% of them were discharged home. The mean oxygen saturation values of the patients for every hour in the Prone position were 93.15±1.718 (p=0.035), 93.60±1.809 (p=0.019), 93.93±1.774 (p=0.006) and 94.15±1.718 (p=0.002), respectively in the first four hours. These findings were statistically significant compared to the Fowler position. Respiratory values

in the prone position were 17.30±1.159 (p=0.005), 17.20±1.344 (p=0.010), 17.20±1.181 (p=0.005), and 17.05±1.280 (p=0.001), respectively in the first four hours, which were statistically lower than in the Fowler position. There was no significant difference in the mean heart rate and blood pressure in both positions (p>0.05).

Conclusion: The prone position was found to have a positive effect on oxygen saturation levels when Fowler and Prone positions were applied in patients receiving treatment with the diagnosis of COVID-19 in hospital wards. Therefore, it is recommended that patients admitted with the diagnosis of COVID-19 be placed in the prone position at regular intervals.
Effect of Online Case-Based Teaching Method on Professional Development of Nursing Students
Authors: EVGİN Derya , SÜMEN Adem
Published: March 2023

Objective: This study was conducted to determine the effect of online case-based education, as part of distance education, on nursing students’ professional values, professional behavior, problem-solving, critical-thinking skills, and self-directed learning skills.

Methods: The study was conducted using a single-group pretest-posttest quasi-experimental design. A total of 58 3rd grade nursing students participated in this study The data before the study were collected electronically with the Google forms application using the personal information forms and scales (Self-Directed Learning Skills Scale, Problem Solving Inventory, California Critical Thinking Disposition Scale, Nurses Professional Values Scale, Nursing Students Professional Behaviors Scale).

Results: After online case-based nursing process teaching, the difference in the total mean score of the students in all scales was found to be statistically significant (p< 0.01). It was found that, after the training had been provided through case-based education, the score average of students’ professional values, professional behaviors, problem-solving, critical thinking skills and self-directed learning increased.

Conclusion: Use of online case-based teaching is useful for increasing nursing students’ nursing skills in distance education.
The Relationship Between Pregnancy-Related Low Back Pain, Kinesiophobia, and Physical Activity in the Third Trimester
Authors: KEPENEK VAROL Büşra , AYDOĞDU Ayşen , TEMUR Esra Nur , FIRAT Göksu , SELVİ Merve , YAZICI-GÜLAY Meltem , AKSOY Hüseyin
Published: March 2023

Objective: The aim of this study is to examine the relationship between pregnancy-related low back pain, kinesiophobia, and physical activity during the third trimester of pregnancy.

Methods: Fifty-one pregnant women between the ages of 18-40, at the gestational age of 27 weeks and above were included in the study. The intensity of pregnancy-related low back pain was assessed with the Numerical Pain Scale, kinesiophobia with the Tampa Kinesiophobia Scale, and physical activity levels with the short form of the International Physical Activity Questionnaire.

Results: Only 4 (7.8%) subjects had high levels of physical activity, 12 (23.5%) had moderate, and 35 (68.6%) had low levels of physical activity. A strong positive correlation was found between low back pain and kinesiophobia in the third trimester of pregnancy (r = 0.796; p < 0.001). There was no statistically significant relationship between low back pain and physical activity or between kinesiophobia and physical activity (r=– 0.097; p= 0.498 and r= – 0.212; p= 0.135 respectively).

Conclusion: Pregnancy-related low back pain can cause kinesiophobia during pregnancy, and kinesiophobia may cause limitations of movements. Considering the negative effects of pregnancy-related low back pain and kinesiophobia during pregnancy, the evaluation of pain, and kinesiophobia by health professionals is important during this period.
COVID-19-Related Obsessions and Its Predictors: A Community- Based Research in Turkey
Authors: ÇINAR TANRIVERDİ Esra , ASLAN CEVHEROĞLU Büşra , ÖZKURT Zülal , ŞAHİNGÖZ Mine
Published: March 2023

Objective: This study aims to investigate the psychological effects of the COVID-19 pandemic on the Turkish society and identify COVID-19-related obsessions and predictive factors.

Methods: This cross-sectional study was performed with 859 volunteer participants. Data were collected using an online questionnaire between 01 and 08 June 2020. A sociodemographic information form, Depression, Anxiety and Stress Scale-21 (DASS-21), Impact of Event Scale-Revised (IES-R), and Obsession with COVID-19 Scale (OSC), were used as data collection tools. Data were analysed using SPSS 20 statistical software.

Results: The mean age of the participants was 40.41± 13.69 (18-70), 55.3% were women, and %63.7 were married. Cleaning habits increased during the pandemic in 76% of the participants. The prevalence of depression, anxiety, and stress symptoms were 36.9%, 42.3%, and 18.2%, respectively. Depression was severe or very severe in 6.3% of the participants, anxiety in 15.4%, and stress in 4.3%. Post-traumatic stress

disorder (PTSD) was determined in 11.3% of the participants, and COVID-19-related obsessions in 17.6%. Obsessions were greater in the variables of eating (r= 0.26, p
Epidemiological Analysis and Management of Patients with Facial Space Infections of Odontogenic Origin: A Retrospective Evaluation of Two Years
Authors: EKİCİ Ömer
Published: March 2023

Objective: Odontogenic infections are one of the most common pathologies in the oral and maxillofacial regions. The spread of odontogenic infections after unsuccessful or late treatment can lead to serious complications. The aim of this study is to examine the epidemiological features and treatment management of patients with odontogenic facial abscesses.

Methods: This retrospective study included 88 patients with odontogenic facial area abscesses treated at Afyonkarahisar health sciences university, faculty of dentistry’s maxillofacial surgery clinic between 2019-2021. The socio-demographic, socio-economic characteristics and clinical examination findings of the patients and treatment methods for odontogenic abscess were analyzed comprehensively. Data were

evaluated using SPSS-20 and the level of significance was set at p < .05.

Results: In the two-year period between 2019 and 2021, 88 patients (44 male and 44 female, mean age was 39.72±16.42) were treated for diffuse facial infections of odontogenic origin. The most commonly involved area was the submandibular area (38.6%), the most affected tooth was mandibular 1st molar and mandibular 3rd molars (18.2%), and the most common cause was dental caries (65.90%). Incision and drainage were performed in half of the patients (36.4% intraoral, 13.6% extraoral). The most commonly used drugs were clindamycin (36.4%), amoxicillin-clavulanate, and ornidazole combination (27.3%).

Conclusion: The results of this study confirm that odontogenic abscesses can heal without complications with timely and effective basic interventions such as incision and drainage. In this study, successful results were obtained with the parenteral clindamycin, and a combination of oral amoxicillin-clavulanate and ornidazole in the treatment of odontogenic abscesses.
Efficacy of PBTZ169 and pretomanid against Mycobacterium avium, Mycobacterium abscessus, Mycobacterium chelonae, and Mycobacterium fortuitum in BALB/c mice models
Authors: Zheng Luyao , Qi Xueting , Zhang Weiyan , Wang Hong , Fu Lei , Wang Bin , Chen Xi , Chen Xiaoyou , Lu Yu
Published: March 2023

Objectives

We aimed to evaluate the activity of PBTZ169 and pretomanid against non-tuberculous mycobacteriosis (NTM) in vitro and in vivo.

Methods

The minimum inhibitory concentrations (MICs) of 11 antibiotics, against slow-growing mycobacteria (SGMs) and rapid-growing mycobacteria (RGMs) were tested using the microplate alamarBlue assay. The in vivo activities of bedaquiline, clofazimine, moxifloxacin, rifabutin, PBTZ169 and pretomanid against four common NTMs were assessed in murine models.

Results

PBTZ169 and pretomanid had MICs of >32 μg/mL against most NTM reference and clinical strains. However, PBTZ169 was bactericidal against Mycobacterium abscessus (3.33 and 1.49 log10 CFU reductions in the lungs and spleen, respectively) and Mycobacterium chelonae (2.29 and 2.24 CFU reductions in the lungs and spleen, respectively) in mice, and bacteriostatic against Mycobacterium avium and Mycobacterium fortuitum. Pretomanid dramatically decreased the CFU counts of M. abscessus (3.12 and 2.30 log10 CFU reductions in the lungs and spleen, respectively), whereas it showed moderate inhibition of M. chelonae and M. fortuitum. Bedaquiline, clofazimine, and moxifloxacin showed good activities against four NTMs in vitro and in vivo. Rifabutin did not inhibit M. avium and M. abscessus in mice.

Conclusion

PBTZ169 appears to be a candidate for treating four common NTM infections. Pretomanid was more active against M. abscessus, M. chelonae and M. fortuitum than against M. avium.
Thematic analyses of participant survey responses following dermatology ECHO programs with dermoscopy: Practical tips and lessons learned
Authors: Black T. Austin , Parbs Joshua R. , Teixeira Anthony J. , Cyr Peggy , Nelson Kelly C. , Stoddard Henry , Seiverling Elizabeth V.
Published: March 2023

Introduction

Skin cancer is a major public health concern in the United States, reflecting approximately one in every three cancer diagnoses. Despite the high incidence of skin cancer, access to dermatologists is limited, especially in rural areas. Primary care physicians play a pivotal role in the evaluation of skin conditions, but dermatology training gaps exist in primary care training programs.

Objectives

This study examines the use of the Project ECHO (Extension for Community Healthcare Outcomes) knowledge-sharing framework to provide dermoscopy and skin cancer detection training to primary care providers (PCPs).

Methods

Responses to surveys administered to participants in two separate dermoscopy-focused Project ECHO courses were analyzed. Survey responses were collected over a 4-year period for the two courses, which were delivered in Maine and Texas. Thematic analysis of the qualitative data was performed, revealing codes and subcodes that indicated several overall trends.

Results

Overall, most respondents indicated the ECHO sessions to be helpful, reporting an increase in confidence and knowledge in dermoscopy. Other codes reflected a positive reception of the learning materials and teaching styles. Furthermore, participant survey analyses highlighted areas of improvement for future ECHO course sessions.

Conclusions

This thematic analysis of Project ECHO courses in dermatology with dermoscopy demonstrates the feasibility of using virtual educational platforms to effectively teach PCPs about dermoscopy and skin cancer, with high levels of participant satisfaction. The need to keeping the educational sessions brief, avoid scheduling sessions on high-volume patient care days, and provide a means for participants to obtain hands-on training in the operation of a dermatoscope were among the top lessons learned.
Vibration and jitter of free-flowing thin liquid sheets as target for high-repetition-rate laser-ion acceleration
Authors: Cao Zhengxuan , Peng Ziyang , Shou Yinren , Zhao Jiarui , Chen Shiyou , Gao Ying , Liu Jianbo , Wang Pengjie , Mei Zhusong , Pan Zhuo , Kong Defeng , Qi Guijun , Xu Shirui , Liu Zhipeng , Liang Yulan , Xu Shengxuan , Song Tan , Chen Xun , Wu Qingfan , Liu Xuan , Ma Wenjun
Published: March 2023

Very thin free-flowing liquid sheets are promising targets for high-repetition-rate laser-ion acceleration. In this work, we report the generation of micrometer-thin free-flowing liquid sheets from the collision of two liquid jets, and study the vibration and jitter in their surface normal direction. The dependence of their motion amplitudes on the generation parameters is studied in detail. The origins of the vibration and jitter are discussed. Our results indicate that when the generation parameters are optimized, the motion amplitudes in the stable region can be stabilized below 3.7 μm to meet the stringent requirement of sheet position stability for a tight-focusing setup in laser-ion acceleration experiments.
Evans Syndrome as a Possible Complication of Brentuximab Vedotin Therapy for Peripheral T Cell Lymphoma
Authors: Irimia Ruxandra , Barbu Sinziana , Popa Codruta , Badelita Sorina
Published: March 2023

Recently, Brentuximab Vedotin (BV) has emerged as an important therapy not only for Hodgkin’s Lymphoma, but also for CD30-positive T cell lymphomas. Although anemia and thrombocytopenia are common myelosuppressive side effects, to our knowledge, this is the first described case of Evans Syndrome associated with BV therapy. We present the case of a 64-year-old female, diagnosed with relapsed Peripheral T Cell Lymphoma Not Otherwise Specified (PTCL-NOS), who, after receiving six cycles of BV, developed authentic severe autoimmune hemolytic anemia with strong positive direct anti-globulin (Coombs) test, simultaneously associated with severe immune thrombocytopenia. The patient was unresponsive to systemic corticotherapy, but fully recovered after a course of IV immunoglobulin.