bluuebunny/crossref_metadata_2025 huggingface dataset:
Konsep Logoterapi untuk Mengatasi Trauma pada Perempuan Korban KDRT
Authors: Septiani* Riska , Nurhanifah Laily , Marisyah Putri Lili
Published: January 2024

Kekerasan dalam rumah tangga (KDRT) tidak terlepas dari adanya ketidaksetaraan gender. Logoterapi mempengaruhi perubahan sikap dan psikologis bagi korban KDRT secara signifikan. Melalui konsep logoterapi, para korban mampu menyadari bahwa mereka dapat mengatasi depresi dengan memaknai kehidupan mereka dan sadar bahwa mereka dapat berjuang untuk mengatasi masalah yang mereka alami. Artikel ini bertujuan untuk membahas tentang konsep logoterapi dalam menangani trauma dan mengurangi depresi pada korban KDRT. Paper ini menggunakan studi literatur yang memanfaatkan tulisan dan hasil penelitian yang berkaitan dengan logoterapi. Hasil penelitian menunjukkan bahwa penggunaan konsep logoterapi dapat mengurangi tingkat depresi pada korban kekerasan dalam rumah tangganya. Korban kekerasan dalam ruah tangga lebih dapat memaknai kehidupannya.
Academic Procrastination of Students at SMAN 6 Prabumulih in Terms of the Intensity of Smartphone Usage
Authors: Putri* Itsmi Annisa , Putri Rani Mega , Alrefi Alrefi
Published: January 2024

This study aims to describe the level of academic procrastination of class XI students at SMAN 6 Prabumulih in terms of the intensity of smartphone usage. The method used in this research is descriptive quantitative. The data collection technique used was by distributing research instruments, namely questionnaires with a Likert scale model. The data obtained were then analyzed using categorization formulas and percentages (%). The population in this study were all 263 students of class XI at SMAN 6 Prabumulih with a sample selected by a simple random technique of 158 students based on the calculation of sampling using the slovin formula. The results of this study indicate that in general students have a medium level of academic procrastination when viewed from the intensity of their smartphone usage.
Pengaruh Efikasi Diri terhadap Keputusan Karir pada Alumni Perguruan Tinggi Samarinda
Authors: Fajriyah* Rizka , Inayah Sitti Syahar , Rayhaniah Sri Ayu
Published: January 2024

Penelitian ini bertujuan untuk mengetahui apakah ada pengaruh efikasi diri terhadap keputusan karir. Peneliti menggunakan pendekatan kuantitatif dengan jenis penelitian korelasi untuk menjawab pertanyaan tersebut. Subjek yang peneliti gunakan adalah alumni Universitas Islam Negeri Sultan Aji Muhammad Idris Samarinda; untuk mendapatkan responden peneliti menggunakan teknik snowball sampling dan didapatkan sebanyak 59 orang yang bersedia berpartisipasi dalam penelitian ini. Peneliti menggunakan skala efikasi diri dan keputusan karir sebagai instrumen utama penelitian. Analisis data yang peneliti gunakan adalah regresi linear sederhana menggunakan program SPSS V24. Dari hasil analisis regresi linier sederhana diperoleh koefisien signifikansi sebesar 0,000 (p < 0,05) dengan demikian dapat dikatakan bahwa efikasi diri memiliki pengaruh yang signifikan terhadap keputusan karir alumni Perguruan Tinggi di Samarinda. Kesimpulan dari penelitian ini adalah tingginya tingkat efikasi diri yang dimiliki alumni dapat meningkatkan kemampuan dalam mengambil keputusan karir. Kemampuan keputusan karir merupakan kemampuan dasar dalam merancang karir yang dapat memudahkan alumni dalam mendapatkan pekerjaan.
KONSEP PENIDIDIKAN ISLAM MODERN-KONTEKSTUAL HAJI RASUL
Authors: Imamah Yuli habibatul
Published: January 2024

Berbicara pendidikan Islam modern khususnya di Indonesia, maka seyogyanya tidak akan melewati bab tentang Haji Rasul dan lembaga pendidikan yang didirikannya. Sebab di tengah kungkungan pola pendidikan konvensional pada pra dan awal kemerdekaan, beliau dengan Sumatra Thawalib-nya menjadi pelopor yang membawa angin segar dan menjadi tonggak lahirnya pendidikan modern pada perjalanan pendidikan Islam selanjutnya. Sumatra Thawalib yang mulanya adalah institusi pendidikan tradisional yang menerapkan pola pendidikan dan kurikulum yang masih tergolong konvensional, mampu digubah oleh Haji Rasul menjadi sebuah institusi pendidikan modern yang dikelola secara professional oleh komite sekolah, tidak lagi menjadi milik individu. Pola pembelajaran yang awalnya berbentuk halaqah seperti umumnya ditemukan pada lembaga-lembaga pendidikan tradisional, dirombak dengan menerapkan pola pembelajaran yang menggunakan sistim kelas untuk penjenjangan dan pembedaan materi pembelajaran. Tulisan ini, berupaya untuk mengupas kembali gagasan-gagasan pendidikan Islam Haji Rasul sehingga mendorong berdirinya Sumatra Thawalib di Minangkabau. Apa saja yang melatarbelakangi dan mempengaruhi konsep pemikiran pendidikan beliau, serta bagaiman pola pembelajaran dan organisasi sekolah yang diterapkan di Sumtra Thawalib, menjadi titik sentral pembahasan tulisan ini.
IMPLEMENTASI METODE PEMBELAJARAN EXPERIENTIAL LEARNING UNTUK MENINGKATKAN AKADEMIK SANTRI SMA PONDOK PESANTREN
Authors: Nicolas Djone Georges , Rk. Timothy Amien , Siahaan Soneta Sang Surya , Ramadhan Iwan , Huriyah Lilik
Published: January 2024

Penelitian ini memiliki tujuan guuna mengetahui tentang metode pembelajaran experiential learning yang dilakukan dalam kehidupan sosial guna meningkatkan akademik santri putri di Pondok Pesantren. Metode penelitian yang digunakan yaitu metode deskriptif analisis dengan melakukan pendekatan di sisi kualitatif. Subjek penelitian dalam proses penelitian ini yaitu santri di Pondok Pesantren. Data dikumpulkan dengan cara melakukan observasi secara partisipan kepada metode pembelajaran di kelas dan juga kegiatan santri yang adai sekitar pondok. Kegiatan wawancara, angket dan juga dokumentasi juga dilakukan sebagai jalan guna menunjang data yang dibutuhkan dalam proses penelitian tersebut. Hasil dari penelitian ini menyajikan bahwasanya metode experiential learning dalam kehidupan sosial dan akademik santri di Pondok Pesantren yang berhubungan dengan proses pembelajaran dan kegiatan santri terlaksana dengan cukup baik dengan berbagai macam upaya yang dilakukan dair pihak Pondok Pesantren. Namun masih ada beberapa kegiatan yang membutuhkan perhatian dan juga ditingkatkan dengan pembuatan perencanaan pembelajaran, kegiatan ekstrakulikuler hingga penyediaan di sektor sarana dan prasarana sekolah.
The Concept Of Education Management In The Post-Conflict Regions Of West Kalimantan: A Study Of Ibn Khaldun’s Thought
Authors: Sahri Sahri
Published: January 2024

This article discusses the management of education in schools in the thought of Ibn Khaldun. The approach used in this study is qualitative, and the type of research is literature research. This research combines data collection techniques with document studies so that data in the form of journals and books related to Ibn Khaldun are used as primary sources in this study and refer to the work of Ibn Khaldun. The data used relates to Ibn Khaldun’s thoughts on Islamic education management. This research shows that, at least in the implementation of education management in schools, four aspects are mutually integrated: educators, students, learning materials, and learning methods. Ibn Khaldun’s perspective on educational management can be applied to educational institutions such as the Madrasah in West Kalimantan. Moreover, educational practices in West Kalimantan are still unable to overcome problems, especially in building an atmosphere of peace between students, both ethnic and religious. Educators in Madrasah, especially in West Kalimantan, can integrate learning materials with tolerance and student backgrounds without raising ethnic or religious stereotypes. The learning method can be done by understanding the material and mapping the material that can be related to building peace in West Kalimantan.
Hadanah Di Pesantren Sains Tebuireng Perspektif Maslahah Mursalah
Authors: Baroroh Khuzaimatul , Al Amin Habibi
Published: January 2024

Abstrak

Pesantren memiliki potensi besar dalam menghasilkan kemaslahatan umum melalui pembentukan kepribadian Islami pada anak-anak. Pengasuhan anak berbasis pesantren dapat membantu melindungi generasi muda dari pengaruh negatif, memperkuat keimanan, mengembangkan kemampuan moral dan etika, serta membentuk individu yang tangguh dan bertanggung jawab. Penulis tertarik untuk melihat pola pengasuhan atau hadanah yang ada di pondok pesantren Trensains Tebuireng dari perspektif maslahah mursalah. Pendekatan yang digunakan dalam penelitian ini adalah metode pendekatan kualitatif. Jenis penelitian ini adalah penelitian lapangan (field reseach), digunakan untuk memperoleh data yang diperlukan dalam mengkaji tentang pola pengasuhan atau hadanah berbasis pesantren yang ada di pesantren Sains Tebuireng lalu dianalisis dengan kacamata maslahah mursalah. Hasil penelitian ini menyimpulkan Hadanah Berbasis Pesantren di pesantren Sains Tebuireng sudah memenuhi aspek-aspek pemeliharaan anak seperti pendidikan, pemenuhan kebutuhan anak, dan usia yang ideal. Selain itu Pesantren Sains Tebuireng komponen-komponen yang menjadi syarat berdirinya pesantren juga sangat memadai, dari mulai Pondok, Kiai, Masjid, Santri, Kitab-Kitab Klasik. Dan, Hadanah di Pesantren Sains Tebuireng sudah sesuai dengan nilai maslahah secara keseluruhan, dari mulai maslahah dharuriyah, hajjiyah, dan tahsiniyah. Selain itu maslahah yang dipraktekkan juga maslahah yang nyata bukan sekedar dugaan, juga tidak bertentangan dengan nash yang ada, kemudian juga maslahah bersifat umum.

Kata Kunci: Hadanah, Maslahah Mursalah, Pesantren.
Science students develop multiple employability literacies from large, early-year courses without employability modules
Authors: Carpenter Lauren , Hubbard Sophie , Basinski Nicole Scout , Rowland Susan
Published: January 2024

Concerns have been raised about the employability of Science graduates, however undergraduate Science curricula rarely focus on building employability. Our goal is to harness existing Science-focused curricula to improve Science graduate employability. In this study we asked whether students could identify learning of employability literacies from their experiences in undergraduate Science courses that do not explicitly teach employability literacies. To address these questions, we employed a short reflective activity in three large first year courses; these courses focused on scientific content and processes, and did not include employability modules. We asked students to choose an employability literacy from a menu and describe how components of the course prompted them to develop this literacy. Students chose a wide variety of literacies and linked their development to multiple aspects of their course experience. They also consistently indicated they had achieved multiple literacies from their course. Course coordinators highlighted the strength-based quality of the reflections, which differed from the usual course evaluation comments given by students. Coordinators who used the reflection activity in the first year were eager to continue in subsequent semesters and years. This mechanism gives students and staff the opportunity to understand the wide and varied opportunities for employability skill development that already exist in undergraduate Science courses. The approach does not require course teaching amendments or student skill-building instruction. This study shows that students can achieve multiple employability literacies from early-year courses, and raises new possibilities around how we can boost students’ understanding and development of their employability.
Inpatient Quality Indicators of General Internal Medicine: Implementation Study with Practicability Assessment and Retrospective Data Analysis
Authors: von Ahlen Christine , Moser Dominik , Schneider Dominik , Geissler Alexander
Published: January 2024

BACKGROUND
In the summer of 2021, the Swiss Society for General Internal Medicine (SGAIM) published six quality indicators for the inpatient sector for the first time. The aim of these indicators is to facilitate a structured quality improvement process in internal medicine. The present implementation study examines the practicability of the quality indicators recommended by the SGAIM.
METHODS
The QUALIFY assessment tool for quality indicators is used to assess the practicability of the SGAIM indicators in a structured manner based on their implementation in a single center. Within this framework, a retrospective data analysis of the years 2020 and 2021 was carried out.
RESULTS
The results were calculated according to the recommended evaluation intervals and were as such: A provisional discharge report within 24 hours was sent to the follow-up institution for an average of 23.7% of discharges. A new prescription of benzodiazepines in patients with an age of ≥ 65 years occurred in an average of 17.2% of patients per month. The fall history was collected from 100% of the patients. The monthly proportion of patients with transfusions with an Hb value of > 8g/dl was 17.9% on average. The proportion of CIRS cases per patient averaged 1.3%. Hepatitis B vaccination protection was available to 100%.
CONCLUSIONS
The quality indicators recommended by the SGAIM for the transmission of provisional discharge reports, new prescriptions for benzodiazepines and transfusions with Hb values > 8 g/dl provided added value in everyday clinical practice CIRS case processing, biography of falls in the last 12 months and hepatitis B vaccination protection did not provide any benefit for practice in their current form.
Study on Proximate Composition of Rice (Oryza sativa) Bran and Chemical Properties with Fatty Acid Content of its’ Extracted Oil Collected from the Northern Region of Bangladesh
Authors: Shandhi Shabiba Parvin
Published: January 2024

Oryza sativa bran was analyzed for its proximate composition. The oil was extracted from the bran by the Soxhlet extraction method. Studies of some chemical properties and analysis of fatty acids by GC-MS of extracted oil were performed in this research work. The bran was collected from the Kurigram district of Bangladesh. The rice bran and the bran oil of this area are not much studied. The studies find out some significant properties and nutritional values of this area's rice bran and bran oil. The bran was rich in carbohydrates (38.78%), fats (20.30%), fiber (1.42%), and proteins (9.45%). Moisture and ash content were found 9.49% and 20.5% respectively. The important minerals were found by wet and dry tests like Fe, Zn, Ca, Mg, K, Na, etc. The higher saponification (110.13 mg KOH/g) value of the oil indicated that it could be used as raw materials in good quality soap. It was determined by refluxing the oil with alcoholic KOH solution followed by titration with standard acid. The low iodine (46.25 I2/100g) value of the oil indicated that it could be used for cooking purposes and the oil was stable and consisted of polyunsaturated fatty acids mainly oleic and linoleic acid. From the fatty acid analysis by GC-MS, it was found that the oil had a high content of fatty acids such as oleic acid, linoleic acid, palmitic acid, stearic acid, etc. These acids have high biological importance for human health.
Causal Relationship Between Systemic Circulatory Inflammatory Regulators and Intervertebral Disc Degeneration: A Bidirectional Two-Sample Mendelian Randomization Study
Authors: Chen Zi-Xuan , Xu Bo , Huang Ze-Ling , Liu Yu-Jiang , Shen Xiao-Feng , Lu Bin-Jie , Lin Jun , Zhang Xian-Da , Li Yu-Wei
Published: January 2024

Background
In the context of the development of Intervertebral Disc Degeneration (IDD), inflammatory mediators play a pivotal role. Nevertheless, due to the influence of the inflammatory microenvironment, the causal relationship between specific inflammatory mediators and the development of IDD remains uncertain. The understanding of the causal relationship between inflammatory mediators and IDD is of great importance in preventing and delaying disc degeneration in the future.
Methods
We utilized genetic data concerning systemic circulating inflammatory regulators obtained from a Genome-Wide Association Study (GWAS) analyzing 41 serum cytokines in a cohort of 8,293 individuals from Finland. The genetic data for IDD was derived from the most recent Genome-Wide Association Study summary statistics conducted within the FinnGen consortium, encompassing 37,636 IDD cases and 270,964 controls. Our analysis employed bidirectional two-sample Mendelian randomization (MR) techniques, which included several MR methods such as MR Egger, weighted median, inverse variance weighted (IVW), weighted mode, and simple mode. Additionally, the MR-PRESSO method was employed to identify horizontal pleiotropy, heterogeneity was quantified using the Cochran Q statistic, and MR Egger intercept analysis was performed to assess pleiotropy.
Results
We established causal relationships between three specific inflammatory factors and IDD. Elevated levels of MIP-1β [OR = 0.956, 95% CI: -0.08 to -0.006; P = 0.02] and IFN-G [OR = 0.915, 95% CI: -0.16 to -0.02; P = 0.01] expression were associated with a reduced risk of IDD. Conversely, genetic susceptibility to IDD was linked to a decrease in IL13 levels [OR = 0.967, 95% CI: -0.063 to -0.004; P = 0.03].
Conclusion
In this study, we have identified inflammatory factors that exhibit a causal relationship with the onset and progression of IDD, as supported by genetic predictions.
Antibacterial Effect of Apis Mellifera Bees Honey, Garlic Extracts and Their Combination Against Salmonella in Wolayta Sodo, Southern Ethiopia
Authors: Mahamed Samatar , Wolde Rediet
Published: January 2024

The use of medicinal plants and preparations for different activities to treat infections is an age-old practice. Interest in plants with antimicrobial properties has come to use again because of the emergence of resistance strains of microorganisms against antimicrobials. Antibiotic resistant salmonella infections in both humans and animals are universal concerns, particularly in developing countries where the risk of infection is high. Garlic has been used for centuries by various societies around the world to combat various pathogens. Honey has proven antimicrobial activity as well. Honey inhibits a broad spectrum of bacterial species. But their use in modern medicine is limited because of a lack of scientific support. An experimental study design was used with the objective of testing honey and garlic aqueous extracts for their antibacterial activity against salmonella. The test microorganism Salmonella was isolated in the Wolaita Sodo regional laboratory from the feces of diarrheal calves. The extracts used were prepared at three concentrations, namely 100g, 50g, 25g in 100 ml of distilled water, and in vitro antibacterial activity was assessed against Salmonella bacteria. For this assessment, a filter paper disc diffusion assay was used. The antibacterial activities of the extracts were expressed as the mean inhibition of salmonella growth. According to the current investigation in all concentrations, tested honey has performed very well than garlic and their combination, but it has highly significantly different mean inhibition than garlic extract and the combination of garlic and honey at 100g concentration with a maximum zone of inhibition of 26.33 ± 0.577mm. The present study reveals the possibility of using honey, garlic, and their combination to treat disease caused by salmonella. Therefore, further studies should be conducted on the antibacterial and other medicinal values of honey and garlic using in vitro and in vivo studies to see how they may contribute to solving the problems of drug resistance.
Astroglia proliferate upon biogenesis of tunneling nanotubes via α-synuclein dependent transient nuclear translocation of focal adhesion kinase
Authors: Nath Sangeeta , Raghavan Abinaya , Kashyap Rachana , P Sreedevi , Jos Sneha , Chatterjee Suchana , Alex Ann , D’Souza Michelle , Giridharan Mridhula , Manjithaya Ravi , Muddashetty Ravi , Padavattan Sivaraman
Published: January 2024

Astroglia play crucial neuroprotective roles by internalizing pathogenic aggregates and facilitating its degradation. Here, we show, that α-SYN protofibril-induced organelle toxicities and reactive oxygen species (ROS) cause premature cellular senescence in astrocytes and astrocytes origin cancer cells, resulting in a transient increase in biogenesis of tunneling nanotubes (TNTs). TNT-biogenesis and TNT-mediated cell-to-cell transfer lead to clearance of α-SYN-induced organelle toxicities, reduction in cellular ROS levels, and reversal of cellular senescence. Enhanced cell proliferation is seen in the post-recovered cells after relieving from α-SYN-induced organelle toxicities. Further, we show, that α-SYN-induced senescence promotes transient localization of focal adhesion kinase (FAK) in the nucleus. FAK-mediated regulation of Rho-associated kinases plays a significant role in the biogenesis of TNTs, and successively proliferation. Our study emphasizes that TNT biogenesis has a potential role in the clearance of α-SYN-induced cellular toxicities and reversal of stress-induced cellular senescence, consequences of which cause enhanced proliferation in the post-recovered astroglia cells.
Lung Cancer and COVID-19 Susceptibility and Severity: A Mendelian Randomization Analysis
Authors: Bai Mengxi , Li Jing
Published: January 2024

It has been observed that lung cancer patients are more susceptible to COVID-19. Establishing the causal relationships between lung cancer and COVID-19 susceptibility and severity is challenging due to numerous confounding factors. Mendelian Randomization (MR) is an effective method to investigate the causal association between exposure and outcome variables. However, different studies have yielded conflicting conclusions regarding the role of lung cancer in COVID-19 susceptibility and severity. Lung cancer subtypes exhibit heterogeneity in genetic susceptibility, which may influence the assessment of the true relationship between lung cancer and COVID-19 susceptibility and severity. In this study, we utilized the most recent COVID-19 association data from The COVID-19 Host Genetics Initiative to conduct a two-sample Mendelian Randomization study. We examined the associations between lung cancer and its four subtypes with COVID-19 susceptibility, hospitalization, and severity. Our data indicates that lung cancer, overall, does not have a causal association with COVID-19 susceptibility, hospitalization, or severity. However, lung cancer in ever smokers is causally associated with COVID-19 hospitalization and increased severity. Additionally, small cell lung carcinoma is causally associated with increased COVID-19 severity.
Movements and habitat use of a nursery area by a wide-ranging species of shark in the southern Caribbean
Authors: Tavares Rafael , Kresge Colby D. , Wetherbee Bradley M.
Published: January 2024

Use of a small tropical nursery in the Los Roques Archipelago by lemon sharks (Negaprion brevirostris) was investigated using acoustic telemetry. Twelve lemon sharks (six female, six male, three each of age classes 0+, 1+, and 2+) were tracked between February 2014 and August 2015 in the Sebastopol Lagoon. Sharks were strongly site attached and remained in the lagoon for the duration of the study. Age 0+ individuals largely restricted their movements within the innermost area of the lagoon in shallow water (< 1 m), over muddy substrate and along mangrove-lined shores. Ages 1+ and 2+ sharks ranged further, in deeper water, over a wider range of substrates and more frequently to areas near the lagoon entrance. Activity space (home range = 95% kernel utilization densities - KUD) was 0.42, 1.11 and 1.15 km2 for age 0+, 1+ and 2+ sharks respectively. Core area (50% KUD) was 0.13, 0.33 and 0.35 km2 for age 0+, 1+ and 2+ sharks respectively. MCP overlap between ages 1+ and 2+ was 89%, in contrast to smaller overlap between ages 0+ and 1+ (40%) and 0+ and 2+ (43%). Abundance of potential prey was greatest along mangroves fringes, decreasing from the innermost lagoon to entrance. Space use of lemon sharks within nurseries of variable characteristics illustrates a consistent balancing of selective pressures on predator avoidance and prey acquisition among inconsistent nursery habitats. Understanding nursery area use aids informed management of lemon shark populations and incorporation of species-wide life history traits for sustainable management practices.
Dissecting causal relationships between primary biliary cholangitis and extrahepatic autoimmune diseases based on Mendelian randomization
Authors: Ma Gang , Yang Jiaqi , Wang Xingguo , Xia Erzhuo , Yu Jiahao , Zhang Miao , Hu Yinan , Ma Shuoyi , Zhou Xia , Fan Qingling , Han Ying , Wang Jingbo
Published: January 2024

Background
As an autoimmune disease, up to 73% of patients with primary biliary cholangitis (PBC) have a combination of extrahepatic autoimmune diseases (EHAIDs); however, the causal relationship between PBC and EHAIDs is unclear.
Methods
The genome-wide association analyses provided 14 GWAS data for PBC and EHAIDs, and bidirectional, two-sample MR analyses were performed to examine the relationship between PBC and EHAIDs.
Results
The analysis using MR provides a strong and meaningful estimation of the bidirectional correlation between PBC and 7 EHAIDs: rheumatoid arthritis, systemic lupus erythematosus, Sjögren's syndrome, systemic sclerosis, autoimmune hypothyroidism, inflammatory bowel disease and ulcerative colitis of its types. In addition, PBC increases the risk of autoimmune thyroid diseases such as autoimmune hyperthyroidism and Graves' disease, as well as multiple sclerosis and psoriasis. Additionally, PBC is identified as a risk factor for Crohn's disease and Celiac disease.
Conclusion
Based on genetic evidence, there may be connections between PBC and specific EHAIDs: not all coexisting EHAIDs induce PBC, and vice versa. This underscores the significance of prioritizing PBC in clinical practice. Additionally, if any liver function abnormalities are observed during treatment or with EHAIDs, it is crucial to consider the possibility of comorbid PBC.
Realization of strong microwave absorption characteristics of Gd 5 Si 2 Ge 2 nanoparticles with materials data-driven discovery
Authors: Bora Pritom J. , Mahanta Bibhusita , Gupta Shalabh , Ramamurthy Praveen C. , Hadimani Ravi L.
Published: January 2024

In this study, we utilized a materials data-driven approach to investigate the microwave absorption characteristics of Gd5Si2Ge2 nanocomposites. These results suggests that Gd5Si2Ge2 nanocomposites possess highly efficient microwave absorption properties. It was observed that varying the loading of the Gd5Si2Ge2 nanoparticles in a polymer matrix, such as polydimethylsiloxane (PDMS), resulted in changes in reflection loss (RL). However, it was also found that simply increasing the loading of the Gd5Si2Ge2 nanoparticles in PDMS did not improve RL performance. To optimize the RL performance, we employed an electromagnetic data-driven methodology. Obtained results predict a remarkable RL of ≤ -60 dB for a composite containing 60 wt% Gd5Si2Ge2 nanoparticles loaded PDMS in the frequency range 8.2–18 GHz. This prediction was supported by experimental data, which showed a minimum RL value of -57 dB with multiple RL≤-10 dB bandwidth. These findings validate the proposed proof of concept of utilizing data-driven methodology to obtain broadband and robust microwave absorption characteristics in Gd5Si2Ge2 nanocomposites.
Psychometric properties of dysphagia handicap index scale for older adults with oropharyngeal dysphagia in China
Authors: Li Laiyou , Ning Sun , LI Qianru , Fan Chaoyan , Li Hongyu , Yang Shuang , Li Yun
Published: January 2024

Background
Oropharyngeal dysphagiaare was important for older adults in the West, but they have not received enough attention from China. This study evaluated the psychometric properties of a oropharyngeal dysphagia evaluation instrument for older Chinese adults .
Methods
A total of 600 older adults were recruited from five nursing homes in one city to complete a 25-item scale. The reliability and validity of the scale was evaluated using multiple assessments, including a content validity assessment, Cronbach’s alpha, an item-to-total correlation test, and exploratory factor analysis.
Results
The scale was divided into three sub-sections:physical(items 1p–9p), functional (items 1f–9f), emotional(items 1e–7e). Cronbach’s alpha was 0.97 for the whole scale and ranged from 0.89 to 0.94 for the four sub-scales. The item-to-total correlation coefficients for the four sub-scales were between 0.63 and 0.92, and the test-retest correlation coefficient was 0.87.
Conclusions
Our results validated the reliability and validity of a scale designed to measure the quality of long-term care services for older Chinese adults with dementia.
Liquefaction Phenomenon Identification from post-Pohang Earthquake 2017, South Korea based Integrated SAR and optical imagery data using a machine-learning approach
Authors: Fadhillah Muhammad Fulki , Hakim Wahyu Luqmanul , Park Sung-Jae , Lee Chang-Wook
Published: January 2024

An interesting liquefaction phenomenon occurred after the 5.6 Mw Pohang earthquake on November 15, 2017. Liquefaction changes soil density due to earthquake vibrations, which in turn causes water to rise and merge with solid soil. Remote sensing data, particularly those obtained with differential interferometric synthetic aperture radar (DInSAR), can be used to determine surface changes and changes in soil moisture. This study used data from the Sentinel-1 C-band from 2016–2020. In addition, optical satellite data were used to determine the changes in water content and soil moisture that occurred after the Pohang earthquake. A combination of spectral bands sensitive to changes in water content were used based on Sentinel-2 and Landsat-8 data. This was correlated with changes in water content, which were analyzed using optical satellite and DInSAR data with a spatial accuracy of 60–80% in comparison with field data. Moreover, the liquefaction susceptibility map has been generated using convolutional neural network with the AUC value is 0.813. However, this research was the initial research to determine the potential of liquefaction in the future based on 2017 Pohang earthquake, and the results can be the reference to improve our understanding of this liquefaction phenomenon.
HACD: A Hybrid Abusive Content Detector based on Convolutional Neural Network and Long Short-Term Memory
Authors: ABDOU Aziz L. NGOU NJIKAM , TAGNE Elie FUTE
Published: January 2024

Social media platforms have recently recorded an increase in users worldwide -the numbers progressively rising every year. Yet this has unfortunately resulted into an increase of offensive content online- including hate speech conveying derogatory remarks about individuals on social platforms ultimately affecting law enforcement measures within communities leading occasionally to loss of human lives or property-damages. Consequently, identifying such problematic material requires extensive research efforts within machine learning and natural language processing fields hence prompting important questions on prevailing solution models. In response, our proposed solution through this paper lies with hybrid models that will combine Convolutional Neural networks (CNN) alongside Long Short-Term Memory (LSTM) techniques to accurately classify textual contents into three distinct groups: hateful/abusive/or neutral categories. As we provide comparability studies between our novel technique against pre-existing LSTM-based models predominantly cited in existing literatures, promising results were obtained in terms of accuracy, precision, recall and F-1 score. Our experiment used the widely regarded "Data Science dataset" (Datascisteven), accepted as a reliable source for research studies.
Drug Therapy Problems among Older Adults in Nursing Home with Integration of Medical and Old-age Care: A Cross-Sectional Study
Authors: Liang Zhuoru , Zheng Guimei , Qin Sibei , Xu Xiayan , Wang Zhenxing , Ye Chenli , Liu Jiang , Liu Jing , Cao Weiling
Published: January 2024

Background: As the aging process speeds up in China, drug therapy problems (DTPs) for older adults (60 years and older) in nursing homes have become serious. “Integration of medical and old-age care” has been introduced to nursing homes, however, whether it has an impact on DTPs is unknown. This study aimed to determine the frequency and type of DTPs among older adults in a nursing home with the integration of medical and old-age care.
Methods: This is an observational and cross-sectional study. Drug use and DTPs of older adults were conducted in June 2023 from a nursing home with integration of medical and old-age care located in Shenzhen, Guangdong province of China.
Results: A total of 249 older adults participated in this study. The mean age was 85.88 years, 62.4% were women. Medications used per person was 4 (SD=2.43). Polypharmacy was recorded in 30.12% of the older adults, and excessive polypharmacy in 3.21%. A total of 73 DTPs were identified, with an average of 0.25 DTPs per older adult. The most frequent DTP was nonadherence or noncompliance (n=30), followed by adverse drug reactions (n=14).
Conclusions: The DTPs were lower among older adults in this medical and old-age care integrated nursing home than previously reported in traditional care nursing homes, however, there is still room for improvement. To reduce DTPs in nursing homes older adults, pharmacists should be introduced, and a regular evaluation of DTPs is also necessary.
Efficacy and Acceptability of Self-Collected Medical Grade Tampon as a Novel Vaginal Sample Collection Tool for the Detection of HPV and STIs
Authors: Milanova Valentina , Lazarova Iva , Mihaylova Kalina , Gomes Michelle , Georgieva Teodora , Multmeier Jan
Published: January 2024

Objective: Cervical cancer remains a significant health concern, particularly in low-income and middle-income countries (LMICs). This study aims to compare the efficacy and suitability of a self-collected tampon for the detection of human papillomavirus (HPV) and sexually transmitted infections (STIs) using qualitative TMA-based assays (Transcription Mediated Amplification; APTIMA ® HPV, APTIMA ® Combo 2 (CT/NG; AC2 from now on) and APTIMA ® Bacterial Vaginosis (BV from now on). Additionally, we assess the acceptability of tampons as a self-collection tool.
Methods: A cohort of 75 female participants aged 18-54 years was recruited through female-focused social networks. Participants provided informed consent and underwent both Health Care Workers (HCW-collected) and self-collected sample collection using the Daye Diagnostic Tampon. Samples were stored in ThinPrep Vials (TP Vial) or Aptima ® Multitest Swab Collection Kit (APTIMA ®) solutions. HPV and STI testing were performed using TMA-based assay on the fully automated Panther ® Platform. Acceptability was assessed through a questionnaire with Likert-scale responses.
Results: The study involved 60 participants who completed the study (80% of recruited participants). The self-collected tampons showed sensitivity and specificity of 66.67% and 90.74% (when rinsed in TP Vial) and 83.33% and 85.42% (when rinsed in APTIMA ®) for HPV detection, respectively. For bacterial vaginosis (BV) detection, the tampons exhibited sensitivity and specificity of 100.0% and 96.43% (TP Vial) and 88.89% and 98.04% (APTIMA), respectively. For detection of chlamydia and gonorrhoea (AC2), the sensitivity and specificity were 100.00% and 100.0% (TP Vial) and 100.00% and 98.31% (APTIMA), respectively. Participants expressed a preference for tampon self-collection over HCW-collected swabs (90%).
Conclusion: Self-collected tampons demonstrated promising diagnostic accuracy to HCW-collected swabs for HPV and STI detection. The tampon self-collection method was well-accepted and preferred by participants, suggesting its potential as an alternative screening tool, particularly in low-resource settings. Further research with larger and more diverse populations is recommended to validate these findings and inform tampon-based self-collection programs for cervical cancer screening. Randomised controlled trials and comparisons with gold standard methods would enhance validation.
Gender and spatial variation of loneliness among adolescents in three South Asia countries: Prevalence and its correlates
Authors: Hasan Md. Khalid , Uddin Helal , Younos Tahmina Bintay , Mukta Nur A Habiba
Published: January 2024

Background The study aimed to explore the gender and spatial variation of loneliness and identify its correlates among in-school adolescents in three South Asian countries.Methods We used Afghanistan, Bangladesh, and Pakistan's latest Global School-based Student Health Survey (GSHS) datasets. A total of 8089 adolescent data were analyzed using multiple logistic regression models after controlling socio-demographic variables. We used STATA 14 to perform the analyses.Results The prevalence of loneliness among male respondents was 12.28 [95% CI: 11.3–13.3] and 18.1 [95% CI: 16.8–19.5] in females. Afghan adolescents' prevalence of loneliness was the height (34.8%), followed by Pakistani (11.4%) and Bangladeshi adolescents (8.4%). For both genders (male and female), loneliness was higher among the adolescents who were school truants, bullied, involved in physical fights, and experienced physical attacks. In addition, both male and female adolescents with anxiety-induced sleep disturbance, current tobacco users, and suicidal ideation had significantly higher odds of loneliness than their counterparts. Moreover, several poor mental health conditions, such as anxiety-induced sleep disturbance, bullying, suicidal ideation, and suicide plan, were significantly associated with higher odds of loneliness among in-school adolescents in Afghanistan, Bangladesh, and Pakistan. Besides, respondents involved in physical fights were more likely to be lonely.Conclusion We explored the gender and spatial variation of loneliness among adolescents in three South Asian countries and found several similarities and differences in prevalence and correlates of loneliness between various sub-groups. Gender-sensitive and spatial target-oriented policies and interventions should be developed and implemented urgently to reduce the prevalence of adolescent loneliness in these three countries. More studies are also recommended to explore the relationship between loneliness and socio-economic, environmental, and health-behavioral factors among adolescents in these countries.
The impact of dose rate on responses of human lens epithelial cells to ionizing irradiation
Authors: Matsuya Yusuke , Sato Tatsuhiko , Yachi Yoshie , Date Hiroyuki , Hamada Nobuyuki
Published: January 2024

The knowledge on responses of human lens epithelial cells (HLECs) to ionizing radiation exposure is important to understand mechanisms of radiation cataracts that are of concern in the field of radiation protection and radiation therapy. However, biological effects in HLECs following protracted exposure have not yet fully been explored. Here, we investigated the temporal kinetics of γ-H2AX foci as a marker for DNA double-strand breaks (DSBs) and cell survival in HLECs after exposure to photon beams at various dose rates, compared to those in human lung fibroblasts (WI-38). In parallel, we quantified the recovery for DSBs and cell survival using a biophysical model. The study revealed that HLECs have a lower DSB repair rate than WI-38 cells. There is no significant impact of dose rate on cell survival in both cell lines in the dose-rate range of 0.033–1.82 Gy/min. In contrast, the experimental residual γ-H2AX foci showed inverse dose rate effects (IDREs) compared to the model prediction, highlighting the importance of the IDREs in evaluating radiation effects on the ocular lens.
Identifying Factors Associated with Post-Traumatic brain injury Depression: The Role of Inflammatory Markers
Authors: Yang Zhen , 王 德龙 , Liu Yang , Yan Hongwang , Cheng Yuanchi
Published: January 2024

Background
Depression is a common emotional and psychiatric complication of traumatic brain injury (TBI) that has significant negative impacts on patient recovery. Despite the importance of identifying and treating depression in TBI patients, there is currently no simple and standardized system available for assessing the likelihood of post-TBI depression. In this study we are aim to explore the clinical value of peripheral blood inflammatory markers in predicting mental disorders after TBI.
Methods
A total of 67 TBI patients in this study were included and divided them into Group A (depression group) or Group B (non-depression group) based on the presence or absence of concomitant psychiatric disorders. We collected relevant clinical data and inflammatory markers from both groups to identify factors influencing post-TBI depression and analyzed their diagnostic efficacy and correlations.
Results
The overall prevalence of mental disorders among TBI patients was found to be 64.18% at the three-month follow-up after injury. Our study revealed that intracranial infection was an independent factor influencing the occurrence of post-TBI depression (OR = 19.873, 95%CI = 6.721 ~ 58.764, P = 0.001). Patients who developed post-TBI depression had significantly higher levels of white blood cells(WBCs), neutrophil percentage, C-reactive protein (CRP), and monocyte levels compared to non-depressed TBI patients. Additionally, WBCs (Pearson = 0.735,P = 0.001), neutrophil percentage (Pearson = 0.742, P = 0.001), and CRP (Pearson = 0.556, P = 0.001) levels were positively correlated with depression severity in TBI patients.
Conclusions
Our findings suggest a high prevalence of post-TBI depression and highlight peripheral inflammatory markers such as WBCs, neutrophil percentage, and CRP levels as potential early diagnostic indicators for this condition. Identifying these factors can facilitate early diagnosis and intervention for post-TBI depression, improving patient outcomes. This study provides evidence for clinicians to develop effective treatment strategies for post-TBI depression and advance our understanding of its mechanisms.
Minor impact of anastomotic leakage in anterior resection for rectal cancer on long-term male urinary and sexual function
Authors: Rutegård Martin , Jutesten Henrik , Buchwald Pamela , Angenete Eva , Lydrup Marie-Louise
Published: January 2024

Purpose
Anastomotic leakage after anterior resection for rectal cancer induces bowel dysfunction, but the influence on urinary and sexual function is largely unknown. This cross-sectional cohort study evaluated long-term effect of anastomotic leakage on urinary and sexual function in male patients.
Methods
Patients operated with anterior resection for rectal cancer in 15 Swedish hospitals 2007–2013 were identified. Anastomotic leakage, and other clinical variables were retrieved from the Swedish Colorectal Cancer Registry and medical records. Urinary and sexual dysfunction were evaluated at 4 to 11 years after surgery using International Prostate Symptom Score, International Index of Erectile Function, and European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire CR29. The effect of anastomotic leakage on average scores of urinary and sexual dysfunction was evaluated as a primary outcome, and the single items permanent urinary catheter and sexual inactivity as secondary outcomes. The association of anastomotic leakage and functional outcomes was analyzed using regression models with adjustment for confounders.
Results
After a median follow-up of 84 months (interquartile range: 67–110), 379 out of 864 eligible men were included. Fifty-nine (16%) patients had anastomotic leakage. Urinary incontinence was more common in the leakage group, with an adjusted mean score difference measured by EORTC QLQ ColoRectal–29 of 8.69 (95% confidence interval: 0.72–16.67). The higher risks of urinary frequency, permanent urinary catheter and sexual inactivity did not reach significance.
Conclusion
Anastomotic leakage after anterior resection had a minor negative impact on urinary and sexual function in men.
Biodegradable Poly(ethylene glycol-glycerol-itaconate-sebacate) Copolyester Elastomer with Significantly Reinforced Mechanical Properties by in-situ Construction of Bacterial Cellulose Interpenetrating Network
Authors: Tang Lisheng , Jin Yuanyuan , He Xiaoyan , Huang Ran
Published: January 2024

To address the concern that biodegradable elastomers are environmental-friendly but usually associated with poor properties for practical utilization, we report a star-crosslinked poly(ethylene glycol-glycerol-itaconate-sebacate) (PEGIS) elastomer synthesized by esterification, polycondensation and UV curing, and reinforced by Bacterial Cellulose (BC). The interpenetrating network of primary BC backbone and vulcanized elastomer is achieved by the “in-situ secondary network construction” strategy. With the well dispersion of BC without agglomeration, the mechanical properties of PEGIS are significantly enhanced in tensile strength, Young's modulus and elongation at break. The reinforcement strategy is demonstrated to be efficient and offers a route to the development of biodegradable elastomers for a variety of applications in the future.
Novel Synthesis of New Triazine Sulfonamides with Antitumor, Antimicrobial and Anti-SARS-CoV-2 Activities
Authors: Mohamed-Ezzat Reham A. , elgemeie galal
Published: January 2024

Novel approach for synthesizing triazine sulfonamide derivatives is accomplished via reacting the sulfaguanidine derivatives with
N-cyanodithioiminocarbonate. Further reaction of the novel triazine sulfonamide analogues were reacted with various secondary amines, anilines and 2-aminothiazole to generate various substituted triazine sulfonamide analogues of promising broad spectrum activities. The in vitro anti-proliferative activities of most of the novel compounds were evaluated on the NCI-60 cell line panel. The antifungal and antibacterial activities of the compounds were also estimated. The antiviral activity against SARS COV-2 virus was performed to evaluate the half-maximal cytotoxic concentration (CC50) and inhibitory concentration 50 (IC50) of a representative compound from the novel triazine sulfonamide category.
Challenges and prospects in integrating abortion care with HIV/Family planning services as a one-stop maternal health service
Authors: Adane Haile Bekele , Lizeth Roets
Published: January 2024

Introduction: Delivering a standalone health service not only reduces the accessibility of comprehensive healthcare at a given time but also diminishes service quality, raises service costs, increases facility visits, and amplifies stigma and discrimination especially given the religious, moral, cultural, and political implications associated with abortion care. Therefore, integrating abortion care with HIV-FP services can enhance the utilization of maternal health services and increase client satisfaction.
Method: A facility-based cross-sectional mixed-method study was conducted, collecting quantitative data through face-to-face interviews with abortion care users and self-administered questionnaires for healthcare providers. The collected data underwent verification, cleaning, and entry into EpiData version 3.1 software, followed by exportation and analysis using SPSS version 25.
Result: The study included 413 women receiving abortion care and 306 healthcare providers from 58 public health facilities. Healthcare providers identified factors such as enhancing regulatory documents, providing training, improving infrastructure, ensuring a consistent supply of medical resources, program monitoring and evaluation, and fostering interaction between healthcare facility units as motivating factors for implementing integrated health services. Abortion care users emphasized that making health facilities available and equipping them with necessary materials, equipment, and supplies can enhance integrated abortion care services.
Conclusion: Successful implementation of integrated maternal health services requires a strategic action plan addressing challenges and engaging with motivational factors.