bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 4 from NOTCH Signaling Regulates Asymmetric Cell Fate of Fast- and Slow-Cycling Colon Cancer–Initiating Cells
Authors: Srinivasan Tara , Walters Jewell , Bu Pengcheng , Than Elaine Bich , Tung Kuei-Ling , Chen Kai-Yuan , Panarelli Nicole , Milsom Jeff , Augenlicht Leonard , Lipkin Steven M. , Shen Xiling
Published: April 2023

Analysis of CCIC-1 with NOTCH suppression.
Supplementary Figure 3 from NOTCH Signaling Regulates Asymmetric Cell Fate of Fast- and Slow-Cycling Colon Cancer–Initiating Cells
Authors: Srinivasan Tara , Walters Jewell , Bu Pengcheng , Than Elaine Bich , Tung Kuei-Ling , Chen Kai-Yuan , Panarelli Nicole , Milsom Jeff , Augenlicht Leonard , Lipkin Steven M. , Shen Xiling
Published: April 2023

MYC knockdown in CCIC-1 line.
Supplementary Figure 2 from NOTCH Signaling Regulates Asymmetric Cell Fate of Fast- and Slow-Cycling Colon Cancer–Initiating Cells
Authors: Srinivasan Tara , Walters Jewell , Bu Pengcheng , Than Elaine Bich , Tung Kuei-Ling , Chen Kai-Yuan , Panarelli Nicole , Milsom Jeff , Augenlicht Leonard , Lipkin Steven M. , Shen Xiling
Published: April 2023

Asymmetry of BMI1+/LGR5+ CCIC-1 pairs.
Supplementary Figure 1 from NOTCH Signaling Regulates Asymmetric Cell Fate of Fast- and Slow-Cycling Colon Cancer–Initiating Cells
Authors: Srinivasan Tara , Walters Jewell , Bu Pengcheng , Than Elaine Bich , Tung Kuei-Ling , Chen Kai-Yuan , Panarelli Nicole , Milsom Jeff , Augenlicht Leonard , Lipkin Steven M. , Shen Xiling
Published: April 2023

Characterization of BMI1+/LGR5+ CCIC-1 asymmetric daughter cell pairs.
Supplementary Figures Legends from The Ubiquitin-like Protein FAT10 Stabilizes eEF1A1 Expression to Promote Tumor Proliferation in a Complex Manner
Authors: Liu Xiuxia , Chen Leifeng , Ge Jin , Yan Chen , Huang Zixi , Hu Junwen , Wen Chongyu , Li Ming , Huang Da , Qiu Yumin , Hao Haibin , Yuan Rongfa , Lei Jun , Yu Xin , Shao Jianghua
Published: April 2023

Supplementary Figures Legends
Supplementary Figure S3 from The Ubiquitin-like Protein FAT10 Stabilizes eEF1A1 Expression to Promote Tumor Proliferation in a Complex Manner
Authors: Liu Xiuxia , Chen Leifeng , Ge Jin , Yan Chen , Huang Zixi , Hu Junwen , Wen Chongyu , Li Ming , Huang Da , Qiu Yumin , Hao Haibin , Yuan Rongfa , Lei Jun , Yu Xin , Shao Jianghua
Published: April 2023

Supplementary Fig. S3 Identification of the Ub binding site in eEF1A1.
Supplementary Figure Legends from KLF4-Mediated Suppression of CD44 Signaling Negatively Impacts Pancreatic Cancer Stemness and Metastasis
Authors: Yan Yongmin , LI Zhiwei , Kong Xiangyu , Jia Zhiliang , Zuo Xiangsheng , Gagea Mihai , Huang Suyun , Wei Daoyan , Xie Keping
Published: April 2023

Supplemental Figure Legends Figure S1. Effects of KLF4 overexpression on tumorsphere formation and liver metastasis of cancer stem-like cells; Figure S2. Effect of Klf4 gene disruption on cell morphology of mouse pancreatic cancer cells; Figure S3. IHC staining of Klf4 and CD44 expressions in intestinal tissues; Figure S4. KLF4 and CD44 expressions in PANC-1 cells; Figure S5. KLF4 inhibits CD44v and ESRP-1 expressions in pancreatic and colon cancer cells; Figure S6. KLF4 expression correlates with metastatic potential in human cancer cells; Figure S7. KLF4/CD44 expressions in primary and metastatic tumor tissues
Supplement TableS1 from The Ubiquitin-like Protein FAT10 Stabilizes eEF1A1 Expression to Promote Tumor Proliferation in a Complex Manner
Authors: Liu Xiuxia , Chen Leifeng , Ge Jin , Yan Chen , Huang Zixi , Hu Junwen , Wen Chongyu , Li Ming , Huang Da , Qiu Yumin , Hao Haibin , Yuan Rongfa , Lei Jun , Yu Xin , Shao Jianghua
Published: April 2023

Primers and shRNA target sequences
Supplemental Figures from miR-17-92/p38α Dysregulation Enhances Wnt Signaling and Selects Lgr6+ Cancer Stem-like Cells during Lung Adenocarcinoma Progression
Authors: Guinot Anna , Oeztuerk-Winder Feride , Ventura Juan-Jose
Published: April 2023

Extra figures including complementary data for the main text: 1. Characterisation of the adenocarcinoma stages using different markers by histology, flow cytometry and mRNA expression 2. Demonstration that p38a is a miR-19 target 3. mRNA expression in Lgr6+ and Lgr6- cells from different stages of lung adenocarcinoma 4. Loss of epithelial markers and gain of Lgr6 expression during adenocarcinoma progression 5. Characterisation of secondary lung tumors induced by tail-vein injection of Lgr6+ cells
Supplementary Figures 1 through 13 from Chronic Stress Facilitates Lung Tumorigenesis by Promoting Exocytosis of IGF2 in Lung Epithelial Cells
Authors: Jang Hyun-Ji , Boo Hye-Jin , Lee Ho Jin , Min Hye-Young , Lee Ho-Young
Published: April 2023

Supplementary Figure 1. Effects of epinephrine and cortisol on the viability and colony formation of human lung epithelial cells. Supplementary Figure 2. Effect of norepinephrine on the phosphorylation of IGF-1R and IR in human lung epithelial cells. Supplementary Figure 3. Increases in IGF-1R phosphorylation by stimulation with beta-adrenergic receptor (beta-AR) agonists in R+ cells but not in R- cells. Supplementary Figure 4. Downregulation of beta-AR agonists-induced IGF-1R phosphorylation by treatment with linsitinib. Supplementary Figure 5. Minimal regulation of IGFBP-3 by short-term NE stimulation. Supplementary Figure 6. Knockdown of RAB27A transcription by siRNA transfection. Supplementary Figure 7. Minimal regulation of IGFBP-3 by long-term NE stimulation. Supplementary Figure 8. Decrease in IGF2 expression by stable knocking down IGF2 levels using shRNAs. Supplementary Figure 9. Attenuation of norepinephrine-induced increases in cell viability by decrease in IGF2 expression. Supplementary Figure 10. Increase in tumoral IGF-1R phosphorylation by exposure to norepinephrine. Supplementary Figure 11. Reduction of tumor incidence by treatment with propranolol or amlodipine. Supplementary Figure 12. Suppression of chronic stress-induced IGF2 secretion in the lungs by blockade of beta-AR or L-type VDCC. Supplementary Figure 13. Decreases in CUS-induced tumoral IGF-1R phosphorylation by blockade of beta-AR or L-type VDCC.
Supplementary Tables from Cyclin E Associates with the Lipogenic Enzyme ATP-Citrate Lyase to Enable Malignant Growth of Breast Cancer Cells
Authors: Lucenay Kimberly S. , Doostan Iman , Karakas Cansu , Bui Tuyen , Ding Zhiyong , Mills Gordon B. , Hunt Kelly K. , Keyomarsi Khandan
Published: April 2023

The attached file includes the 6 different supplementary tables as described below Supplementary Table 1: Clinicopathologic characteristics of 100 patients with invasive breast cancer Supplementary Table 2: Interacting proteins of LMW-E(T1) identified from RePCA screen Supplementary Table 3: Doubling time (hrs.) of 76NE6 TDCs+KD ACLY Supplementary Table 4: ACLY inhibition delays tumor formation Supplementary Table 5: Adipophilin, Ki-67 and LMW-E immuno- expression in xenograft tumors Supplementary Table 6 : Adipophilin scoring system
Supplementary Figure 2 from Cyclin E Associates with the Lipogenic Enzyme ATP-Citrate Lyase to Enable Malignant Growth of Breast Cancer Cells
Authors: Lucenay Kimberly S. , Doostan Iman , Karakas Cansu , Bui Tuyen , Ding Zhiyong , Mills Gordon B. , Hunt Kelly K. , Keyomarsi Khandan
Published: April 2023

ACLY downregulation in LMW-E TDCs does not affect the cell cycle.
Supplementary Table S1 from Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198
Authors: Molenaar Remco J. , Botman Dennis , Smits Myrthe A. , Hira Vashendriya V. , van Lith Sanne A. , Stap Jan , Henneman Peter , Khurshed Mohammed , Lenting Krissie , Mul Adri N. , Dimitrakopoulou Dionysia , van Drunen Cornelis M. , Hoebe Ron A. , Radivoyevitch Tomas , Wilmink Johanna W. , Maciejewski Jaroslaw P. , Vandertop W. Peter , Leenders William P. , Bleeker Fonnet E. , van Noorden Cornelis J.
Published: April 2023

SPSS output statistics for comparisons between survival curves from colony-formation assays.
Supplemental Figure legends from Cyclin E Associates with the Lipogenic Enzyme ATP-Citrate Lyase to Enable Malignant Growth of Breast Cancer Cells
Authors: Lucenay Kimberly S. , Doostan Iman , Karakas Cansu , Bui Tuyen , Ding Zhiyong , Mills Gordon B. , Hunt Kelly K. , Keyomarsi Khandan
Published: April 2023

The file includes supplemental figure legends to all the supplemental figures
Supplementary Figure S2 from Radioprotection of IDH1-Mutated Cancer Cells by the IDH1-Mutant Inhibitor AGI-5198
Authors: Molenaar Remco J. , Botman Dennis , Smits Myrthe A. , Hira Vashendriya V. , van Lith Sanne A. , Stap Jan , Henneman Peter , Khurshed Mohammed , Lenting Krissie , Mul Adri N. , Dimitrakopoulou Dionysia , van Drunen Cornelis M. , Hoebe Ron A. , Radivoyevitch Tomas , Wilmink Johanna W. , Maciejewski Jaroslaw P. , Vandertop W. Peter , Leenders William P. , Bleeker Fonnet E. , van Noorden Cornelis J.
Published: April 2023

D-2HG inhibits IDH-mediated NADPH production capacity, but not G6PD-mediated NADPH production capacity or IDH-mediated NADH production capacity.
Supplementary Table 2 from RK-33 Radiosensitizes Prostate Cancer Cells by Blocking the RNA Helicase DDX3
Authors: Xie Min , Vesuna Farhad , Tantravedi Saritha , Bol Guus M. , Heerma van Voss Marise R. , Nugent Katriana , Malek Reem , Gabrielson Kathleen , van Diest Paul J. , Tran Phuoc T. , Raman Venu
Published: April 2023

Correlation between DDX3 expression and other immunohistochemical markers in prostate cancer patient's samples
Supplementary Table 1 from RK-33 Radiosensitizes Prostate Cancer Cells by Blocking the RNA Helicase DDX3
Authors: Xie Min , Vesuna Farhad , Tantravedi Saritha , Bol Guus M. , Heerma van Voss Marise R. , Nugent Katriana , Malek Reem , Gabrielson Kathleen , van Diest Paul J. , Tran Phuoc T. , Raman Venu
Published: April 2023

Clinical characteristics of patients with low and high DDX3 expression
Supplementary Figure Legends from RK-33 Radiosensitizes Prostate Cancer Cells by Blocking the RNA Helicase DDX3
Authors: Xie Min , Vesuna Farhad , Tantravedi Saritha , Bol Guus M. , Heerma van Voss Marise R. , Nugent Katriana , Malek Reem , Gabrielson Kathleen , van Diest Paul J. , Tran Phuoc T. , Raman Venu
Published: April 2023

Supplementary Figure Legends
SUPPLEMENTARY figure 2 from IGFBP2 Activates the NF-κB Pathway to Drive Epithelial–Mesenchymal Transition and Invasive Character in Pancreatic Ductal Adenocarcinoma
Authors: Gao Song , Sun Yan , Zhang Xuebin , Hu Limei , Liu Yuexin , Chua Corrine Yingxuan , Phillips Lynette M. , Ren He , Fleming Jason B. , Wang Huamin , Chiao Paul J. , Hao Jihui , Zhang Wei
Published: April 2023

Morphologic and motility changes in IGFBP2-overexpressing and -knockdown PDAC cells.
Supplementary Figure S4 from Deep Sequencing Reveals a Novel miR-22 Regulatory Network with Therapeutic Potential in Rhabdomyosarcoma
Authors: Bersani Francesca , Lingua Marcello Francesco , Morena Deborah , Foglizzo Valentina , Miretti Silvia , Lanzetti Letizia , Carrà Giovanna , Morotti Alessandro , Ala Ugo , Provero Paolo , Chiarle Roberto , Singer Samuel , Ladanyi Marc , Tuschl Thomas , Ponzetto Carola , Taulli Riccardo
Published: April 2023

Gene expression profiling of miR-22-expressing RD18 cells identifies TACC1 and RAB5B as direct targets.
Supplementary Figure S1 from Deep Sequencing Reveals a Novel miR-22 Regulatory Network with Therapeutic Potential in Rhabdomyosarcoma
Authors: Bersani Francesca , Lingua Marcello Francesco , Morena Deborah , Foglizzo Valentina , Miretti Silvia , Lanzetti Letizia , Carrà Giovanna , Morotti Alessandro , Ala Ugo , Provero Paolo , Chiarle Roberto , Singer Samuel , Ladanyi Marc , Tuschl Thomas , Ponzetto Carola , Taulli Riccardo
Published: April 2023

miRNA expression profile reveals a strong distinction between muscle and RMS.
Supplementary Figure 3 from PAK4 Phosphorylates p53 at Serine 215 to Promote Liver Cancer Metastasis
Authors: Xu Hai-Tao , Lai Wai-Lung , Liu Heong-Fai , Wong Leo Lap-Yan , Ng Irene Oi-Lin , Ching Yick Pang
Published: April 2023

HLE cells were transfected with siRNA of PAK4 (siPAK4; 200pmol/ml) or negative control (siControl; 200pmol/ml) for 48 hours
Supplementary Figure Legends from Deep Sequencing Reveals a Novel miR-22 Regulatory Network with Therapeutic Potential in Rhabdomyosarcoma
Authors: Bersani Francesca , Lingua Marcello Francesco , Morena Deborah , Foglizzo Valentina , Miretti Silvia , Lanzetti Letizia , Carrà Giovanna , Morotti Alessandro , Ala Ugo , Provero Paolo , Chiarle Roberto , Singer Samuel , Ladanyi Marc , Tuschl Thomas , Ponzetto Carola , Taulli Riccardo
Published: April 2023

Legends for Supplementary Figures
Figure S5 from UGT2B17 Expedites Progression of Castration-Resistant Prostate Cancers by Promoting Ligand-Independent AR Signaling
Authors: Li Haolong , Xie Ning , Chen Ruiqi , Verreault Mélanie , Fazli Ladan , Gleave Martin E. , Barbier Olivier , Dong Xuesen
Published: April 2023

Figure S5: UGT2B17 protein expression is correlated with pAR Y534 and pSrc Y416 levels in PCa cell lines
Supplemental Material from αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor
Authors: Lu Huimin , Wang Tao , Li Jing , Fedele Carmine , Liu Qin , Zhang Jianzhong , Jiang Zhong , Jain Dhanpat , Iozzo Renato V. , Violette Shelia M. , Weinreb Paul H. , Davis Roger J. , Gioeli Daniel , FitzGerald Thomas J. , Altieri Dario C. , Languino Lucia R.
Published: April 2023

Supplemental Methods, Figures and Legends
Supplemental Figures from TPL2 Is an Oncogenic Driver in Keratocanthoma and Squamous Cell Carcinoma
Authors: Lee Jun-Han , Lee Joo-Hyung , Lee Sang Hyuk , Do Sung-Im , Cho Sung-Dae , Forslund Ola , Inn Kyung-Soo , Lee Jeong-Sang , Deng Fang-Ming , Melamed Jonathan , Jung Jae U. , Jeong Joseph H.
Published: April 2023

Supplementary Fig. S1 - Generation of inducible TPL2 transgenic (iTPL2 TG) mice. Supplementary Fig. S2 - Percentage of tumor-free for iTPL2 TG mice ON DOX Supplementary Fig. S3 - Detection of transgene TPL2 expression using an antibody against HA epitope tag (A) and three different antibodies against TPL2 (B) in an iTPL2 wt (#100) TG-driven KA-like cSCC ON DOX. Supplementary Fig. S4 - A, effects on TPL2-related signaling pathways with the treatments of indicated inhibitors in stable cell lines, overexpressing either control vector (Vector), TPL2-WT, or TPL2-IN, by western blot. Supplementary Fig. S5 - Western blot analyses of normal mouse skin samples Supplementary Fig. S6 - For In vitro kinase assay Supplementary Fig. S7 -Co-immunofluorescence of TPL2 Supplementary Fig. S8 - Quantification of each staining with iTPL2 TG-driven cSCC
Supplementary Methods from Extracellular Matrix/Integrin Signaling Promotes Resistance to Combined Inhibition of HER2 and PI3K in HER2+ Breast Cancer
Authors: Hanker Ariella B. , Estrada Mónica Valeria , Bianchini Giampaolo , Moore Preston D. , Zhao Junfei , Cheng Feixiong , Koch James P. , Gianni Luca , Tyson Darren R. , Sánchez Violeta , Rexer Brent N. , Sanders Melinda E. , Zhao Zhongming , Stricker Thomas P. , Arteaga Carlos L.
Published: April 2023

This file contains Supplementary Methods.
Supplementary Data from Micellar Delivery of miR-34a Modulator Rubone and Paclitaxel in Resistant Prostate Cancer
Authors: Wen Di , Peng Yang , Lin Feng , Singh Rakesh K. , Mahato Ram I.
Published: April 2023

Figure S1 showed the effect of miR-34a on prostate cancer cell viability. Figure S2 characterized the PEG-PCD polymer. Figure S3 evaluated polymer stability. Figure S4 determined organ toxicity of our formulation.
Supplementary Figures from Extracellular Matrix/Integrin Signaling Promotes Resistance to Combined Inhibition of HER2 and PI3K in HER2+ Breast Cancer
Authors: Hanker Ariella B. , Estrada Mónica Valeria , Bianchini Giampaolo , Moore Preston D. , Zhao Junfei , Cheng Feixiong , Koch James P. , Gianni Luca , Tyson Darren R. , Sánchez Violeta , Rexer Brent N. , Sanders Melinda E. , Zhao Zhongming , Stricker Thomas P. , Arteaga Carlos L.
Published: April 2023

Supplementary Figure 1. HER2+/PIK3CAH1047R mammary tumors acquire resistance to trastuzumab + pertuzumab + BKM120 in vivo. Supplementary Figure 2. Primary tumor cells (PTCs) derived from TPB-resistant tumors are sensitive to TPB in vitro. Supplementary Figure 3. Collagen reduces sensitivity to TPB in human breast cancer cells. Supplementary Figure 4. TbRI inhibition does not affect Collagen-induced TPB resistance. Supplementary Figure 5. Collagen deposition is enhanced in residual drug-resistant tumors following neoadjuvant anti-HER2 therapy.
Time-lapse videomicroscopy of HT-29 colonic cancer cells treated with CDDP from A Squalene-Based Nanomedicine for Oral Treatment of Colon Cancer
Authors: Kotelevets Larissa , Chastre Eric , Caron Joachim , Mougin Julie , Bastian Gerard , Pineau Alain , Walker Francine , Lehy Therese , Desmaële Didier , Couvreur Patrick
Published: April 2023

Video 2 shows that HT-29 cells treated with 8 microM CDDP still proliferated and generated large cell clusters.
Time-lapse videomicroscopy of HT-29 colonic cancer cells treated with CDDP NP from A Squalene-Based Nanomedicine for Oral Treatment of Colon Cancer
Authors: Kotelevets Larissa , Chastre Eric , Caron Joachim , Mougin Julie , Bastian Gerard , Pineau Alain , Walker Francine , Lehy Therese , Desmaële Didier , Couvreur Patrick
Published: April 2023

Video 3 shows the toxicity of SQ-CDDP NP (8 microM) on HT-29 cells.
Supplemental Figure Legends from TALEN-Mediated Inactivation of PD-1 in Tumor-Reactive Lymphocytes Promotes Intratumoral T-cell Persistence and Rejection of Established Tumors
Authors: Menger Laurie , Sledzinska Anna , Bergerhoff Katharina , Vargas Frederick Arce , Smith Julianne , Poirot Laurent , Pule Martin , Herrero Javier , Peggs Karl S. , Quezada Sergio A.
Published: April 2023

Legends for supplemental figures
Supplementary Materials and Methods, Supplementary Tables I and II, and Supplementary Figure Legends from A Squalene-Based Nanomedicine for Oral Treatment of Colon Cancer
Authors: Kotelevets Larissa , Chastre Eric , Caron Joachim , Mougin Julie , Bastian Gerard , Pineau Alain , Walker Francine , Lehy Therese , Desmaële Didier , Couvreur Patrick
Published: April 2023

Supplementary Materials and Methods, Supplementary Tables I and II, and Supplementary Figure Legends
Supplementary Figures 1-13 from A Squalene-Based Nanomedicine for Oral Treatment of Colon Cancer
Authors: Kotelevets Larissa , Chastre Eric , Caron Joachim , Mougin Julie , Bastian Gerard , Pineau Alain , Walker Francine , Lehy Therese , Desmaële Didier , Couvreur Patrick
Published: April 2023

Supplementary Figure 1 shows the viability of cancer cell lines treated with drugs. Supplementary Figure 2 demonstrates the cytotoxicity of CDDP and SQ-CDDP NP on primary culture of mice rectal tumors. Supplementary Figure 3 illustrates the relative mRNA expression levels of CTR1, CCS, ATP7A, ATP7B, MRP2, GSTP1 and MT2A involved in CDDP influx/efflux, intracellular trafficking and detoxification in a series of human carcinoma cell lines. Supplementary Figure 4 shows the contribution of CTR1 influx transporter and the copper transporter ATP7A in the cellular accumulation of CDDP or SQ-CDDP NP. Supplementary Figure 5 shows the comparative effects of SQ-CCDP NP and CDDP on the effectors systems involved in CDDP resistance of the colonic KM-12 cancer cells. Supplementary Figure 6 and 7 show the stability of SQ-CDDP NP and drug release in simulated digestive fluids and pharmacokinetic analysis of platinum. Supplementary Figure 8 shows the overall toxicity of CDDP and SQ-CCDP NP administered orally in mice. Supplementary Figure 9 shows the relative tissue platinum biodistribution. Supplementary Figure 10 shows the toxicity of CDDP and SQ-CCDP NP on colonic epithelial cells in vivo. Supplementary Figure 11 shows the anticancer efficacy of orally administered SQ-CCDP NP versus CDDP injected iv on the development of colonic tumors induced by AOM/DSS in Balb/c mice. Supplementary Figure 12 shows the tissue distribution of platinum after multiple oral administration of CDDP and SQ-CDDP NP to Balb/c mice. Supplementary Figure 13 shows the inhibition of liver and lymph nodes metastasis in intracecal orthotopic graft in nude mice.
Supplementary Table S2 from Histone H3K27 Trimethylation Modulates 5-Fluorouracil Resistance by Inhibiting PU.1 Binding to the DPYD Promoter
Authors: Wu Rentian , Nie Qian , Tapper Erin E. , Jerde Calvin R. , Dunlap Garrett S. , Shrestha Shikshya , Elraiyah Tarig A. , Offer Steven M. , Diasio Robert B.
Published: April 2023

gRNA list.
Supplementary Figure Legends from Histone H3K27 Trimethylation Modulates 5-Fluorouracil Resistance by Inhibiting PU.1 Binding to the DPYD Promoter
Authors: Wu Rentian , Nie Qian , Tapper Erin E. , Jerde Calvin R. , Dunlap Garrett S. , Shrestha Shikshya , Elraiyah Tarig A. , Offer Steven M. , Diasio Robert B.
Published: April 2023

Legend for Supplementary Figures S1-S6.
Supplementary Figure S3 from PTEN Signaling in the Postnatal Perivascular Progenitor Niche Drives Medulloblastoma Formation
Authors: Zhu Guo , Rankin Sherri L. , Larson Jon D. , Zhu Xiaoyan , Chow Lionel M.L. , Qu Chunxu , Zhang Jinghui , Ellison David W. , Baker Suzanne J.
Published: April 2023

Pten deletion caused a massive increase in tumor vasculature in Pten;Tp53 dKO medulloblastomas compared to Tp53 cKO medulloblastomas.
Supplementary Tables from NRBP2 Overexpression Increases the Chemosensitivity of Hepatocellular Carcinoma Cells via Akt Signaling
Authors: Zhang Lixing , Ge Chao , Zhao Fangyu , Zhang Yang , Wang Xin , Yao Ming , Li Jinjun
Published: April 2023

Several tables contain the nucleotide sequences, antibodies information, the correlation between NRBP2 and clinicopathological features and the mass spectrometric analysis results.
Supplementary Figure Legends from PTEN Signaling in the Postnatal Perivascular Progenitor Niche Drives Medulloblastoma Formation
Authors: Zhu Guo , Rankin Sherri L. , Larson Jon D. , Zhu Xiaoyan , Chow Lionel M.L. , Qu Chunxu , Zhang Jinghui , Ellison David W. , Baker Suzanne J.
Published: April 2023

Supplementary Figure legends
Supplementary Methods from ERK and p38 MAPK Activities Determine Sensitivity to PI3K/mTOR Inhibition via Regulation of MYC and YAP
Authors: Muranen Taru , Selfors Laura M. , Hwang Julie , Gallegos Lisa L. , Coloff Jonathan L. , Thoreen Carson C. , Kang Seong A. , Sabatini David M. , Mills Gordon B. , Brugge Joan S.
Published: April 2023

Description of additional methods and procedures used in the study.
Supplemental Methos from v-Src Oncogene Induces Trop2 Proteolytic Activation via Cyclin D1
Authors: Ju Xiaoming , Jiao Xuanmao , Ertel Adam , Casimiro Mathew C. , Di Sante Gabriele , Deng Shengqiong , Li Zhiping , Di Rocco Agnese , Zhan Tingting , Hawkins Adam , Stoyanova Tanya , Andò Sebastiano , Fatatis Alessandro , Lisanti Michael P. , Gomella Leonard G. , Languino Lucia R. , Pestell Richard G.
Published: April 2023

Detail description of microarray analysis and comparison with cancer stem cell dataset, and TMA of prostate cancer patients
Supplementary Tables from Melanoma Lesions Independently Acquire T-cell Resistance during Metastatic Latency
Authors: Zhao Fang , Sucker Antje , Horn Susanne , Heeke Christina , Bielefeld Nicola , Schrörs Barbara , Bicker Anne , Lindemann Monika , Roesch Alexander , Gaudernack Gustav , Stiller Mathias , Becker Jürgen C. , Lennerz Volker , Wölfel Thomas , Schadendorf Dirk , Griewank Klaus , Paschen Annette
Published: April 2023

Tab. S1: Genes covered in the applied sequencing Panel; Tab. S2: List of vaccine peptides
Supplementary Fig S5 from Gemcitabine Mechanism of Action Confounds Early Assessment of Treatment Response by 3′-Deoxy-3′-[18F]Fluorothymidine in Preclinical Models of Lung Cancer
Authors: Schelhaas Sonja , Held Annelena , Wachsmuth Lydia , Hermann Sven , Honess Davina J. , Heinzmann Kathrin , Smith Donna-Michelle , Griffiths John R. , Faber Cornelius , Jacobs Andreas H.
Published: April 2023

200 mg/kg gemcitabine affect growth of A549 xenografts.
Supplementary Materials and Methods from Melanoma Lesions Independently Acquire T-cell Resistance during Metastatic Latency
Authors: Zhao Fang , Sucker Antje , Horn Susanne , Heeke Christina , Bielefeld Nicola , Schrörs Barbara , Bicker Anne , Lindemann Monika , Roesch Alexander , Gaudernack Gustav , Stiller Mathias , Becker Jürgen C. , Lennerz Volker , Wölfel Thomas , Schadendorf Dirk , Griewank Klaus , Paschen Annette
Published: April 2023

Additional information about experimental techniques and materials relevant to this study
Supplementary Fig S4 from Gemcitabine Mechanism of Action Confounds Early Assessment of Treatment Response by 3′-Deoxy-3′-[18F]Fluorothymidine in Preclinical Models of Lung Cancer
Authors: Schelhaas Sonja , Held Annelena , Wachsmuth Lydia , Hermann Sven , Honess Davina J. , Heinzmann Kathrin , Smith Donna-Michelle , Griffiths John R. , Faber Cornelius , Jacobs Andreas H.
Published: April 2023

Gemcitabine induces increased apoptosis in H1975 tumors on d5.
Supplementary Fig S3 from Gemcitabine Mechanism of Action Confounds Early Assessment of Treatment Response by 3′-Deoxy-3′-[18F]Fluorothymidine in Preclinical Models of Lung Cancer
Authors: Schelhaas Sonja , Held Annelena , Wachsmuth Lydia , Hermann Sven , Honess Davina J. , Heinzmann Kathrin , Smith Donna-Michelle , Griffiths John R. , Faber Cornelius , Jacobs Andreas H.
Published: April 2023

TS and hENT1 expression are not altered 6 h after gemcitabine.
Supplementary Figure Legends from Melanoma Lesions Independently Acquire T-cell Resistance during Metastatic Latency
Authors: Zhao Fang , Sucker Antje , Horn Susanne , Heeke Christina , Bielefeld Nicola , Schrörs Barbara , Bicker Anne , Lindemann Monika , Roesch Alexander , Gaudernack Gustav , Stiller Mathias , Becker Jürgen C. , Lennerz Volker , Wölfel Thomas , Schadendorf Dirk , Griewank Klaus , Paschen Annette
Published: April 2023

Legends
Supplementary Fig S2 from Gemcitabine Mechanism of Action Confounds Early Assessment of Treatment Response by 3′-Deoxy-3′-[18F]Fluorothymidine in Preclinical Models of Lung Cancer
Authors: Schelhaas Sonja , Held Annelena , Wachsmuth Lydia , Hermann Sven , Honess Davina J. , Heinzmann Kathrin , Smith Donna-Michelle , Griffiths John R. , Faber Cornelius , Jacobs Andreas H.
Published: April 2023

Ki67 immunohistochemical staining.
Table S3 from Analysis of Liver Tumor-Prone Mouse Models of the Hippo Kinase Scaffold Proteins RASSF1A and SAV1
Authors: Zhang Xiaoying , Guo Cai , Wu Xiwei , Li Arthur X. , Liu Limin , Tsark Walter , Dammann Reinhard , Shen Hui , Vonderfecht Steven L. , Pfeifer Gerd P.
Published: April 2023

Supplemental Table with tumor specimen information
Supplementary Table 14 from Improving the Performance of Somatic Mutation Identification by Recovering Circulating Tumor DNA Mutations
Authors: Fu Yu , Jovelet Cécile , Filleron Thomas , Pedrero Marion , Motté Nelly , Boursin Yannick , Luo Yufei , Massard Christophe , Campone Mario , Levy Christelle , Diéras Véronique , Bachelot Thomas , Garrabey Julie , Soria Jean-Charles , Lacroix Ludovic , André Fabrice , Lefebvre Celine
Published: April 2023

details of DNA concentrations and mutation allele frequencies in plasma analyses of 117 metastatic cases.
Supplementary Figures from Analysis of Liver Tumor-Prone Mouse Models of the Hippo Kinase Scaffold Proteins RASSF1A and SAV1
Authors: Zhang Xiaoying , Guo Cai , Wu Xiwei , Li Arthur X. , Liu Limin , Tsark Walter , Dammann Reinhard , Shen Hui , Vonderfecht Steven L. , Pfeifer Gerd P.
Published: April 2023

Supplementary Figures: Figure S1: Genotyping of Rassf1a and Sav1 mutant mice. Figure S2: Liver from a Sav1+/+ Rassf1a-/- mouse. Figure S3: Liver from a Sav1+/- Rassf1a-/- mouse. Figure S4: Liver size and weight of gene-targeted mice. Figure S5: Gene ontology analysis of differentially expressed genes using the DAVID tool. Figure S6: DNA methylation analysis of the RASSF1A and SAV1 genes in human liver cancer specimens. Figure S7: DNA methylation analysis of the Mst1 and Mst2 genes in human liver cancer specimens. Figure S8: Methylation and expression of MST1 and MST2 in human HCC.
Supplementary Table 11 from Improving the Performance of Somatic Mutation Identification by Recovering Circulating Tumor DNA Mutations
Authors: Fu Yu , Jovelet Cécile , Filleron Thomas , Pedrero Marion , Motté Nelly , Boursin Yannick , Luo Yufei , Massard Christophe , Campone Mario , Levy Christelle , Diéras Véronique , Bachelot Thomas , Garrabey Julie , Soria Jean-Charles , Lacroix Ludovic , André Fabrice , Lefebvre Celine
Published: April 2023

Quality metrics for the targeted sequencing of the 46 plasma samples.
Supplementary Figures S1-S6 from JARID1B Enables Transit between Distinct States of the Stem-like Cell Population in Oral Cancers
Authors: Facompre Nicole D. , Harmeyer Kayla M. , Sole Xavier , Kabraji Sheheryar , Belden Zachary , Sahu Varun , Whelan Kelly , Tanaka Koji , Weinstein Gregory S. , Montone Kathleen T. , Roesch Alexander , Gimotty Phyllis A. , Herlyn Meenhard , Rustgi Anil K. , Nakagawa Hiroshi , Ramaswamy Sridhar , Basu Devraj
Published: April 2023

Characterization of G0-like OSCC cells (S1); Characterization of JARID1Bhigh OSCC cells (S2); Functional analysis of JARID1Bhigh OSCC cells (S3); Molecular analysis of G0-like and JARID1Bhigh OSCC cells (S4); Characterization of G0-like and EGFPhigh fractions under normal and JARID1B-depleted conditions (S5); Activation and inhibition of PI3K-Akt signaling pathway in OSCC cells (S6).
Supplementary Table 1 from HTLV-1 Viral Factor HBZ Induces CCR4 to Promote T-cell Migration and Proliferation
Authors: Sugata Kenji , Yasunaga Jun-ichirou , Kinosada Haruka , Mitobe Yuichi , Furuta Rie , Mahgoub Mohamed , Onishi Chiho , Nakashima Kazutaka , Ohshima Koichi , Matsuoka Masao
Published: April 2023

Immunohistochemical analysis of CCR4, CD103 and Ki67 in skin lesions of five ATL patients
Supplementary Figure 5 from HTLV-1 Viral Factor HBZ Induces CCR4 to Promote T-cell Migration and Proliferation
Authors: Sugata Kenji , Yasunaga Jun-ichirou , Kinosada Haruka , Mitobe Yuichi , Furuta Rie , Mahgoub Mohamed , Onishi Chiho , Nakashima Kazutaka , Ohshima Koichi , Matsuoka Masao
Published: April 2023

CD103, CCR4 and Ki67 expression in skin lesions of ATL patients.
Supplementary Table 2 from Destabilization of Fatty Acid Synthase by Acetylation Inhibits De Novo Lipogenesis and Tumor Cell Growth
Authors: Lin Huai-Peng , Cheng Zhou-Li , He Ruo-Yu , Song Lei , Tian Meng-Xin , Zhou Li-Sha , Groh Beezly S. , Liu Wei-Ren , Ji Min-Biao , Ding Chen , Shi Ying-Hong , Guan Kun-Liang , Ye Dan , Xiong Yue
Published: April 2023

List of FASN-interacting proteins identified by TAP-MS
Supplementary Figure 4 from AIMP2 Controls Intestinal Stem Cell Compartments and Tumorigenesis by Modulating Wnt/β-Catenin Signaling
Authors: Yum Min Kyu , Kang Jong-Seol , Lee Al-Eum , Jo Young-Woo , Seo Ji-Yun , Kim Hyun-A , Kim Yoon-Young , Seong Jinwoo , Lee Eun Byul , Kim Ji-Hoon , Han Jung Min , Kim Sunghoon , Kong Young-Yun
Published: April 2023

The role of AIMP2 in intestinal Wnt signaling is dependent on β-catenin destruction complex.
Supplementary Information from Survival of Head and Neck Cancer Cells Relies upon LZK Kinase-Mediated Stabilization of Mutant p53
Authors: Edwards Zoe C. , Trotter Eleanor W. , Torres-Ayuso Pedro , Chapman Phil , Wood Henry M. , Nyswaner Katherine , Brognard John
Published: April 2023

One supplementary table that quantifies cells in G1 following LZK depletion. Six supplementary figures that examine LZK expression in HNSCC (Figure S1), support the function of LZK to regulate proliferation and mouse model controls (Figure S2 and S3); examine signaling pathways regulated by LZK (Figure S4); demonstrate depletion of GOF mutant p53 suppresses viability (Figure S5); and assesses the role of MDM2/4 in regulation of the cell cycle by LZK.
Tables S1-S6 from Hypoxia-Induced Downregulation of DUSP-2 Phosphatase Drives Colon Cancer Stemness
Authors: Hou Pei-Chi , Li Yo-Hua , Lin Shih-Chieh , Lin Shau-Chieh , Lee Jenq-Chang , Lin Bo-Wen , Liou Jing-Ping , Chang Jang-Yang , Kuo Ching-Chuan , Liu Yi-Min , Sun H. Sunny , Tsai Shaw-Jenq
Published: April 2023

Table S1. CSC frequency measured by ELDA in vitro. Table S2. Multiple corrections for correlation p value. Table S3. Tumor incidence in limiting dilution assay (I). Table S4. Tumor incidence in limiting dilution assay (II). Table S5. Top 10 list of candidate drugs exert similar actions like DUSP2. Table S6: IC50 of B369, B390, and SAHA determined by different methods.
Supplementary figure legends from Mesothelial Cells Create a Novel Tissue Niche That Facilitates Gastric Cancer Invasion
Authors: Tanaka Masamitsu , Kuriyama Sei , Itoh Go , Maeda Daichi , Goto Akiteru , Tamiya Yutaro , Yanagihara Kazuyoshi , Yashiro Masakazu , Aiba Namiko
Published: April 2023

Legends of supplementary figure 1-7
Supplementary Figure 7 from Mesothelial Cells Create a Novel Tissue Niche That Facilitates Gastric Cancer Invasion
Authors: Tanaka Masamitsu , Kuriyama Sei , Itoh Go , Maeda Daichi , Goto Akiteru , Tamiya Yutaro , Yanagihara Kazuyoshi , Yashiro Masakazu , Aiba Namiko
Published: April 2023

Models of PMC-mediated gastric cancer progression.
Figure S5 from Hypoxia-Induced Downregulation of DUSP-2 Phosphatase Drives Colon Cancer Stemness
Authors: Hou Pei-Chi , Li Yo-Hua , Lin Shih-Chieh , Lin Shau-Chieh , Lee Jenq-Chang , Lin Bo-Wen , Liou Jing-Ping , Chang Jang-Yang , Kuo Ching-Chuan , Liu Yi-Min , Sun H. Sunny , Tsai Shaw-Jenq
Published: April 2023

Knockdown of DUSP2 facilitates xenograft tumor growth
Supplementary Figure 6 from Mesothelial Cells Create a Novel Tissue Niche That Facilitates Gastric Cancer Invasion
Authors: Tanaka Masamitsu , Kuriyama Sei , Itoh Go , Maeda Daichi , Goto Akiteru , Tamiya Yutaro , Yanagihara Kazuyoshi , Yashiro Masakazu , Aiba Namiko
Published: April 2023

Peritoneal metastasis of human gastric cancer, and effects of ALDH inhibition on tumor growth.
Figure S2 from Hypoxia-Induced Downregulation of DUSP-2 Phosphatase Drives Colon Cancer Stemness
Authors: Hou Pei-Chi , Li Yo-Hua , Lin Shih-Chieh , Lin Shau-Chieh , Lee Jenq-Chang , Lin Bo-Wen , Liou Jing-Ping , Chang Jang-Yang , Kuo Ching-Chuan , Liu Yi-Min , Sun H. Sunny , Tsai Shaw-Jenq
Published: April 2023

Knockdown of DUSP2 enhanced EMT process and migration/invasion ability
Supplementary Figure 5 from Mesothelial Cells Create a Novel Tissue Niche That Facilitates Gastric Cancer Invasion
Authors: Tanaka Masamitsu , Kuriyama Sei , Itoh Go , Maeda Daichi , Goto Akiteru , Tamiya Yutaro , Yanagihara Kazuyoshi , Yashiro Masakazu , Aiba Namiko
Published: April 2023

Effects of ALDH inhibition on cancer cells, PMCs and CAFs.
Supplementary Figure 4 from Mesothelial Cells Create a Novel Tissue Niche That Facilitates Gastric Cancer Invasion
Authors: Tanaka Masamitsu , Kuriyama Sei , Itoh Go , Maeda Daichi , Goto Akiteru , Tamiya Yutaro , Yanagihara Kazuyoshi , Yashiro Masakazu , Aiba Namiko
Published: April 2023

Wnt3a-mediated PMC infiltration was blocked byDKK1183-266.
Table S2 from Mismatch Repair Proteins Initiate Epigenetic Alterations during Inflammation-Driven Tumorigenesis
Authors: Maiuri Ashley R. , Peng Michael , Podicheti Ram , Sriramkumar Shruthi , Kamplain Caitlin M. , Rusch Douglas B. , DeStefano Shields Christina E. , Sears Cynthia L. , O'Hagan Heather M.
Published: April 2023

Significantly differentially methylated regions for MBD-seq data
Figure S1-S7 from FBW7 Loss Promotes Chromosomal Instability and Tumorigenesis via Cyclin E1/CDK2–Mediated Phosphorylation of CENP-A
Authors: Takada Mamoru , Zhang Weiguo , Suzuki Aussie , Kuroda Taruho S. , Yu Zhouliang , Inuzuka Hiroyuki , Gao Daming , Wan Lixin , Zhuang Ming , Hu Lianxin , Zhai Bo , Fry Christopher J. , Bloom Kerry , Li Guohong , Karpen Gary H. , Wei Wenyi , Zhang Qing
Published: April 2023

Supplemental Figures for "FBW7 loss promotes chromosomal instability and tumorigenesis via Cyclin E1/CDK2-mediated phosphorylation of CENP-A"
Supplementary Materials and Methods from ZIC5 Drives Melanoma Aggressiveness by PDGFD-Mediated Activation of FAK and STAT3
Authors: Satow Reiko , Nakamura Tomomi , Kato Chiaki , Endo Miku , Tamura Mana , Batori Ryosuke , Tomura Shiori , Murayama Yumi , Fukami Kiyoko
Published: April 2023

Supplementary Materials and Methods of plasmids, siRNA, shRNA, transfections, western blot analysis, reagents, luciferase reporter assays, chromatin immunoprecipitation, immunocytochemistry, immunohistochemistry, scratch assays, cell proliferation assays, cell cycle analysis, quantitative real-time PCR, migration and invasion assays, animal experiments, microarray analysis, apoptosis assays, and generation of vemurafenib-resistant cell lines.
Supplementary Figures S1-S6 from Targeting Adenosine in BRAF-Mutant Melanoma Reduces Tumor Growth and Metastasis
Authors: Young Arabella , Ngiow Shin Foong , Madore Jason , Reinhardt Julia , Landsberg Jennifer , Chitsazan Arash , Rautela Jai , Bald Tobias , Barkauskas Deborah S. , Ahern Elizabeth , Huntington Nicholas D. , Schadendorf Dirk , Long Georgina V. , Boyle Glen M. , Hölzel Michael , Scolyer Richard A. , Smyth Mark J.
Published: April 2023

This file contains Supplementary Figure S1A-B, Figure S2A, Figure S3-F, Figure S4A-B, Figure S5A-E and Figure S6A. Figure S1. CD73 expression in melanoma does not associate with survival. Figure S2. Hematopoietic A2AR-deficiency reduces inducible BRAF-mutated tumor growth. Figure S3. A2AR inhibition enhances CD8+ T and NK cell infiltration into the tumor microenvironment. Figure S4. SOX10 expression is present in skin and BRAF-mutated, PTENdeficient tumors. Figure S5. A2AR and BRAF inhibition in combination provides improved tumor control. Figure S6. BRAF and MEK downregulate tumor-derived CD73 expression.
Supplementary Table 4 from Genomic Alterations in Circulating Tumor DNA from Diverse Cancer Patients Identified by Next-Generation Sequencing
Authors: Schwaederle Maria , Chattopadhyay Ranajoy , Kato Shumei , Fanta Paul T. , Banks Kimberly C. , Choi In Sil , Piccioni David E. , Ikeda Sadakatsu , Talasaz AmirAli , Lanman Richard B. , Bazhenova Lyudmila , Kurzrock Razelle
Published: April 2023

List of potentially actionable alterations per patient
Figure S5 from SGK1 Is a Critical Component of an AKT-Independent Pathway Essential for PI3K-Mediated Tumor Development and Maintenance
Authors: Orlacchio Arturo , Ranieri Michela , Brave Martina , Arciuch Valeria Antico , Forde Toni , De Martino Daniela , Anderson Karen E. , Hawkins Phillip , Di Cristofano Antonio
Published: April 2023

Combined pharmacological targeting of PI3K and SGKs at a constant inhibitors ratio does not result in synergistic activity.
Supplementary Table 2 from Genomic Alterations in Circulating Tumor DNA from Diverse Cancer Patients Identified by Next-Generation Sequencing
Authors: Schwaederle Maria , Chattopadhyay Ranajoy , Kato Shumei , Fanta Paul T. , Banks Kimberly C. , Choi In Sil , Piccioni David E. , Ikeda Sadakatsu , Talasaz AmirAli , Lanman Richard B. , Bazhenova Lyudmila , Kurzrock Razelle
Published: April 2023

68 gene panel (ctDNA) comprising amplifications in 16 genes as well as some fusions and indels.
Figure S1 from SGK1 Is a Critical Component of an AKT-Independent Pathway Essential for PI3K-Mediated Tumor Development and Maintenance
Authors: Orlacchio Arturo , Ranieri Michela , Brave Martina , Arciuch Valeria Antico , Forde Toni , De Martino Daniela , Anderson Karen E. , Hawkins Phillip , Di Cristofano Antonio
Published: April 2023

Expression of AKT1, AKT2, and AKT3 in wildt ype and Pten-/- mouse thyroids.
Figure S8 from Androgen Receptor Variants Mediate DNA Repair after Prostate Cancer Irradiation
Authors: Yin Yi , Li Rui , Xu Kangling , Ding Sentai , Li Jeffrey , Baek GuemHee , Ramanand Susmita G. , Ding Sam , Liu Zhao , Gao Yunpeng , Kanchwala Mohammed S. , Li Xiangyi , Hutchinson Ryan , Liu Xihui , Woldu Solomon L. , Xing Chao , Desai Neil B. , Feng Felix Y. , Burma Sandeep , de Bono Johann S. , Dehm Scott M. , Mani Ram S. , Chen Benjamin P.C. , Raj Ganesh V.
Published: April 2023

DNA-PKc inhibitor (DNA-PKc i) in combination with IR and ADT to effectively target PCa cells.
Supplementary Table 1 from ARHGAP18 Downregulation by miR-200b Suppresses Metastasis of Triple-Negative Breast Cancer by Enhancing Activation of RhoA
Authors: Humphries Brock , Wang Zhishan , Li Yunfei , Jhan Jing-Ru , Jiang Yiguo , Yang Chengfeng
Published: April 2023

A brief summary of three mouse orthotopic mammary xenograft tumor studies
Supplementary Figure 6 from ARHGAP18 Downregulation by miR-200b Suppresses Metastasis of Triple-Negative Breast Cancer by Enhancing Activation of RhoA
Authors: Humphries Brock , Wang Zhishan , Li Yunfei , Jhan Jing-Ru , Jiang Yiguo , Yang Chengfeng
Published: April 2023

ARHGAP18 re-expression in miR-200b stably expressing cells reverses the effect of miR-200b on actin cytoskeleton reorganization and RhoA activation
Figure S5 from Androgen Receptor Variants Mediate DNA Repair after Prostate Cancer Irradiation
Authors: Yin Yi , Li Rui , Xu Kangling , Ding Sentai , Li Jeffrey , Baek GuemHee , Ramanand Susmita G. , Ding Sam , Liu Zhao , Gao Yunpeng , Kanchwala Mohammed S. , Li Xiangyi , Hutchinson Ryan , Liu Xihui , Woldu Solomon L. , Xing Chao , Desai Neil B. , Feng Felix Y. , Burma Sandeep , de Bono Johann S. , Dehm Scott M. , Mani Ram S. , Chen Benjamin P.C. , Raj Ganesh V.
Published: April 2023

ChIP-seq analysis of R1-D567
Figure S4 from Androgen Receptor Variants Mediate DNA Repair after Prostate Cancer Irradiation
Authors: Yin Yi , Li Rui , Xu Kangling , Ding Sentai , Li Jeffrey , Baek GuemHee , Ramanand Susmita G. , Ding Sam , Liu Zhao , Gao Yunpeng , Kanchwala Mohammed S. , Li Xiangyi , Hutchinson Ryan , Liu Xihui , Woldu Solomon L. , Xing Chao , Desai Neil B. , Feng Felix Y. , Burma Sandeep , de Bono Johann S. , Dehm Scott M. , Mani Ram S. , Chen Benjamin P.C. , Raj Ganesh V.
Published: April 2023

ARVs are recruited to DNA damage sites.
Figure S3 from Androgen Receptor Variants Mediate DNA Repair after Prostate Cancer Irradiation
Authors: Yin Yi , Li Rui , Xu Kangling , Ding Sentai , Li Jeffrey , Baek GuemHee , Ramanand Susmita G. , Ding Sam , Liu Zhao , Gao Yunpeng , Kanchwala Mohammed S. , Li Xiangyi , Hutchinson Ryan , Liu Xihui , Woldu Solomon L. , Xing Chao , Desai Neil B. , Feng Felix Y. , Burma Sandeep , de Bono Johann S. , Dehm Scott M. , Mani Ram S. , Chen Benjamin P.C. , Raj Ganesh V.
Published: April 2023

Response profile of subcutaneous PCa xenografts to RT
Supplementary Figure 1 from ARHGAP18 Downregulation by miR-200b Suppresses Metastasis of Triple-Negative Breast Cancer by Enhancing Activation of RhoA
Authors: Humphries Brock , Wang Zhishan , Li Yunfei , Jhan Jing-Ru , Jiang Yiguo , Yang Chengfeng
Published: April 2023

Stably expressing miR-200b in TNBC cells reduces focal adhesion turnover
Supplemental Figures 1-3 and Supplemental Tables 1-2 from ILK Induction in Lymphoid Organs by a TNFα–NF-κB–Regulated Pathway Promotes the Development of Chronic Lymphocytic Leukemia
Authors: Krenn Peter W. , Hofbauer Sebastian W. , Pucher Susanne , Hutterer Evelyn , Hinterseer Elisabeth , Denk Ursula , Asslaber Daniela , Ganghammer Sylvia , Sternberg Christina , Neureiter Daniel , Aberger Fritz , Wickström Sara A. , Egle Alexander , Greil Richard , Hartmann Tanja N.
Published: April 2023

Supplemental Figure 1: ILK protein expression in viable CD5+/CD19+ primary CLL cells was assessed by flow cytometry; Supplemental Figure 2: ILK levels are upregulated upon activated T cell and alternative IL2/CpG induced CLL cell activation; Supplemental Figure 3: Control experiments undermine that ILK transcription is regulated in a CD40L independent but highly specific NF-kB dependent manner; Supplemental Table 1: Patient characteristics; Supplemental Table 2: List of used antibodies.
Supplementary Figures and Legends from SPIN90 Depletion and Microtubule Acetylation Mediate Stromal Fibroblast Activation in Breast Cancer Progression
Authors: You Eunae , Huh Yun Hyun , Kwon Ahreum , Kim So Hee , Chae In Hee , Lee Ok-Jun , Ryu Je-Hwang , Park Min Ho , Kim Ga-Eon , Lee Ji Shin , Lee Kun Ho , Lee Yong-Seok , Kim Jung-Woong , Rhee Sangmyung , Song Woo Keun
Published: April 2023

Figure S1 (Related to Fig. 1). Low expression of SPIN90 in cancer stroma and CAFs. Figure S2 (Related to Fig. 2). CAFs derived from Spin90-/- mice show increased activation. Figure S3 (Related to Fig. 3). Loss of SPIN90 induces CAF differentiation. Figure S4 (Related to Fig. 4). Recruitment of mDia2 to acetylated microtubules regulates CAF differentiation. Figure S5 (Related to Fig. 5). Acetylated α-tubulin enhances nuclear translocation of YAP on 0.5 kPa PAGs. Figure S6 (Related to Fig. 6). Increased α-tubulin acetylation in Spin90-/- mice induces cancer progression. Table S1. Primers used for RT-PCR
Figure S3 from TP53INP1 Downregulation Activates a p73-Dependent DUSP10/ERK Signaling Pathway to Promote Metastasis of Hepatocellular Carcinoma
Authors: Ng Kai-Yu , Chan Lok-Hei , Chai Stella , Tong Man , Guan Xin-Yuan , Lee Nikki P , Yuan Yunfei , Xie Dan , Lee Terence K , Dusetti Nelson J , Carrier Alice , Ma Stephanie
Published: April 2023

Western Blot assay to show abolishment of pERK1/2 upon addition of ERK inhibitor U0126.
Supplementary Figures from LSD1-Mediated Epigenetic Reprogramming Drives CENPE Expression and Prostate Cancer Progression
Authors: Liang Yi , Ahmed Musaddeque , Guo Haiyang , Soares Fraser , Hua Junjie T. , Gao Shuai , Lu Catherine , Poon Christine , Han Wanting , Langstein Jens , Ekram Muhammad B. , Li Brian , Davicioni Elai , Takhar Mandeep , Erho Nicholas , Karnes R. Jeffrey , Chadwick Dianne , van der Kwast Theodorus , Boutros Paul C. , Arrowsmith Cheryl H. , Feng Felix Y. , Joshua Anthony M. , Zoubeidi Amina , Cai Changmeng , He Housheng H.
Published: April 2023

Figures S1-2: LSD1 reprogramming in CRPC. Figure S3: Clinical relevance of CENPE in CRPC. Figures S4-8: Regulation and Function of CENPE in CRPC. Figure S9: Inhibition of CENPE in xenograft model.
Figure S2 from TP53INP1 Downregulation Activates a p73-Dependent DUSP10/ERK Signaling Pathway to Promote Metastasis of Hepatocellular Carcinoma
Authors: Ng Kai-Yu , Chan Lok-Hei , Chai Stella , Tong Man , Guan Xin-Yuan , Lee Nikki P , Yuan Yunfei , Xie Dan , Lee Terence K , Dusetti Nelson J , Carrier Alice , Ma Stephanie
Published: April 2023

Effects of TP53INP1 shRNAs on migration and invasion was rescued by TP53INP1 overexpression, ruling out potential off-target effects of the knockdown shRNAs.
Supplementary Materials and Methods from Loss of Tumor Suppressor STAG2 Promotes Telomere Recombination and Extends the Replicative Lifespan of Normal Human Cells
Authors: Daniloski Zharko , Smith Susan
Published: April 2023

The supplemental materials and methods provides details of plasmids, general methods of transfection and infection, methods use for the supplemental figures, and supplemental references.
Supplementary Figure Legends from Loss of Tumor Suppressor STAG2 Promotes Telomere Recombination and Extends the Replicative Lifespan of Normal Human Cells
Authors: Daniloski Zharko , Smith Susan
Published: April 2023

Figure Legends for Supplemental Figures 1-3. Supplemental Figure 1: Figure S1 provides a list of the STAG2 tumor cell lines used in this study and immunoblot analysis of SA1 and SA2 protein expression in the STAG2 cell lines and relates to Figure 1. Supplementary Figure 2: Figure S2 provides analysis of telomere sister chromatid exchange in HCT116 WT and SA2 KO cells and relates to Figure 3. Supplementary Figure 3: Figure S3 provides analysis of telomere cohesion, telomere sister chromatid exchange, growth, DNA damage, senescence, telomere length, and aneuploidy of BJ-1 and BJ-2 SA2-depleted stable cell lines and relates to Figure 6.
Supplementary Table S2 from Autocrine BMP-4 Signaling Is a Therapeutic Target in Colorectal Cancer
Authors: Yokoyama Yuichiro , Watanabe Toshiaki , Tamura Yusuke , Hashizume Yoshinobu , Miyazono Kohei , Ehata Shogo
Published: April 2023

Analysis of the factors associated with disease-free survival of CRC.
Figure S2 from Loss of Tumor Suppressor STAG2 Promotes Telomere Recombination and Extends the Replicative Lifespan of Normal Human Cells
Authors: Daniloski Zharko , Smith Susan
Published: April 2023

Figure S2 provides analysis of telomere sister chromatid exchange in HCT116 WT and SA2 KO cells and relates to Figure 3.
Supplementary Figure S5 from Autocrine BMP-4 Signaling Is a Therapeutic Target in Colorectal Cancer
Authors: Yokoyama Yuichiro , Watanabe Toshiaki , Tamura Yusuke , Hashizume Yoshinobu , Miyazono Kohei , Ehata Shogo
Published: April 2023

U0126 accelerates apoptosis of CRC cells by U0126 (related to Figure 6).