bluuebunny/crossref_metadata_2025 huggingface dataset:
ARMC5 Alterations in Primary Macronodular Adrenal Hyperplasia (PMAH) and the Clinical State of Variant Carriers
Authors: Kyo Chika , Usui Takeshi , Kosugi Rieko , Torii Mizuki , Yonemoto Takako , Ogawa Tatsuo , Kotani Masato , Tamura Naohisa , Yamamoto Yutaro , Katabami Takuyuki , Kurihara Isao , Saito Kohei , Kanamoto Naotetsu , Fukuoka Hidenori , Wada Norio , Murabe Hiroyuki , Inoue Tatsuhide
Published: August 2019

Context

Primary macronodular adrenal hyperplasia (PMAH) is a rare type of Cushing or subclinical Cushing syndrome and is associated with bilateral multinodular formation. ARMC5 is one of the responsible genes for PMAH.

Objectives

This study was performed to identify the genotype-phenotype correlation of ARMC5 in a cohort of Japanese patients.

Patients and Methods

Fourteen patients with clinically diagnosed PMAH and family members of selected patients were studied for ARMC5 gene alteration and clinical phenotype. The associated nonadrenal tumor tissues were also studied.

Results

Of fourteen patients with PMAH, 10 had pathogenic or likely pathogenic variants of ARMC5. We found two variants. Five unrelated patients had identical variants (p.R619*). In two patients, the variant was found in offspring with the asymptomatic or presymptomatic state. Six of ten patients who tested positive for the ARMC5 pathogenic or likely pathogenic variant carried nonadrenal tumors; however, no loss of heterozygosity (LOH) or second hit of the ARMC5 gene was evident. The ARMC5 variant–positive group showed a significantly higher basal cortisol level. Furthermore, age-dependent cortisol hypersecretion was seen in the ARMC5 variant–positive group.

Conclusions

ARMC5 pathogenic variants are common (71%) in Japanese patients with PMAH. p.R619* might be a hot spot in Japanese patients with PMAH. Asymptomatic or presymptomatic pathogenic variant carriers were found among the family members of the patients. Although 50% of ARMC5 variant carriers had nonadrenal neoplastic lesions, no LOH or second hit of ARMC5 in the tumor tissues was evident. The ARMC5 variant–positive mutant group showed a higher basal cortisol level than the negative group.
The Egalitarian binding partners Dynein light chain and Bicaudal-D act sequentially to link mRNA to the Dynein motor
Authors: Goldman Chandler H. , Neiswender Hannah , Veeranan-Karmegam Rajalakshmi , Gonsalvez Graydon B.
Published: August 2019

A conserved mechanism of polarity establishment is the localization of mRNA to specific cellular regions. Although it is clear that many mRNAs are transported along microtubules, much less is known about the mechanism by which these mRNAs are linked to microtubule motors. The RNA binding protein Egalitarian (Egl) is necessary for localization of several mRNAs in Drosophila oocytes and embryos. Egl also interacts with Dynein light chain (Dlc) and Bicaudal-D (BicD). The role of Dlc and BicD in mRNA localization has remained elusive. Both proteins are required for oocyte specification, as is Egl. Null alleles in these genes result in an oogenesis block. In this report, we used an shRNA-depletion strategy to overcome the oogenesis block. Our findings reveal that the primary function of Dlc is to promote Egl dimerization. Loss of dimerization compromises the ability of Egl to bind RNA. Consequently, Egl is not bound to cargo, and is not able to efficiently associate with BicD and the Dynein motor. Our results therefore identify the key molecular steps required for assembling a localization-competent mRNP.
Ahi1 promotes Arl13b ciliary recruitment, regulates Arl13b stability and is required for normal cell migration
Authors: Muñoz-Estrada Jesús , Ferland Russell J.
Published: August 2019

Mutations in the Abelson-helper integration site 1 (AHI1) gene are associated with neurological/neuropsychiatric disorders, and cause the neurodevelopmental ciliopathy Joubert syndrome (JBTS). Here, we show that deletion of the transition zone (TZ) protein Ahi1 in mouse embryonic fibroblasts (MEFs) has a small effect on cilia formation. However, Ahi1 loss in these cells results in: (1) reduced localization of the JBTS-associated protein Arl13b to the ciliary membrane, (2) decreased sonic hedgehog signaling, (3) and an abnormally elongated ciliary axoneme accompanied by an increase in ciliary IFT88 concentrations. While no changes in Arl13b levels are detected in crude cell membrane extracts, loss of Ahi1 significantly reduced the level of non-membrane-associated Arl13b and its stability via the proteasome pathway. Exogenous expression of Ahi1–GFP in Ahi1−/− MEFs restored ciliary length, increased ciliary recruitment of Arl13b and augmented Arl13b stability. Finally, Ahi1−/− MEFs displayed defects in cell motility and Pdgfr-α-dependent migration. Overall, our findings support molecular mechanisms underlying JBTS etiology that involve: (1) disruptions at the TZ resulting in defects of membrane- and non-membrane-associated proteins to localize to primary cilia, and (2) defective cell migration.

This article has an associated First Person interview with the first author of the paper.
Quantitative assessment of early Type 2 diabetic cataracts using T1,T2-mapping techniques
Authors: Ma Junchao , Xu Xiaotong , Wang Shaoyu , Wang Ruifeng , Yu Nan
Published: August 2019

Objective:

The purpose of this study was to explore the feasibility of T1 and T2-mapping techniques in evaluating early Type 2 diabetic cataracts.

Methods:

Totally, 28 patients with Type 2 diabetes was prospectively collected, and 28 non-diabetic patients were collected as control group. All patients included had ophthalmological exploration and all patients underwent orbital MRI examination with T1 and T2-mapping on a Siemens-Skyra 3.0T scanner. T1 and T2 values of the lens nucleus were measured by region of interest (ROI) method based on Siemens-Syngo workstation. Two sample t-test was used to analyze the differences between groups. Pearson correlations were calculated between relaxation time (T1, T2) and clinical variables, such as fasting glucose, glycosylated hemoglobin etc. p < 0.01 was used to determine statistical significance.

Results:

In Type 2 diabetes group, the T1 value was 626.7 ± 56.8, T2 value was 29.4 ± 5.6. In non-diabetic group, the T1 value was 581.6 ± 64.7, T2 value was 24.8 ± 8.6. The T1 and T2 values of the lens in diabetic group were significantly higher than those in control group (p < 0.01, T1 value: 626.7 ± 56.8 vs 581.6 ± 64.7; T2 value: 29.4 ± 5.6 vs 24.8 ± 8.6). The T1 and T2 values of lens in diabetic patients were significantly correlated with glycosylated hemoglobin (HbA1c), and the correlation coefficients were 0.502 and 0.396, respectively.

Conclusion:

T1 and T2-mapping technique can sensitively reflect the alterative relaxation time of lens in diabetic patients. This technique can find abnormal changes earlier than slit lamp, and may be effective diagnostic methods for early lens disease.

Advances in knowledge:

T1 and T2-mapping techniques may be effective diagnostic methods for early lens disease, which can detect abnormal changes earlier than slit lamp examination.
The Role of Japan-India Security Cooperation under the New Security Framework
Authors: Nagao Saturo
Published: August 2019

In recent times Japan and India are moving closer in the area of security. The rise of China, US strategic withdrawal from the Indian Ocean and Japan‟s increasing profile in the Asia-pacific region have contributed towards Japan‟s strong security partnership with India. In this regard this article analyses the three following questions: (1) What are the security activities that Japan has undertaken? (2) Why has Japan tried to share more security burden? (3) What can Japan-India cooperation do? Currently, Japan has enhanced its security cooperation with other US allies and friendly countries including Southeast Asian countries taking the US-China power balance into consideration. The changing security situation has pushed Japan to reconsider its security priorities. There is much scope for Japan and India to cooperate by using the linkage of East China Sea and Indo-China Border, share the burden of maritime security in the Indian Ocean region and collaborate to support countries around China in the South China Sea.
Pedagogic Spaces and Identities: Film as Text
Authors: Bonjour Mini Mark
Published: August 2019

This article aims to explore pedagogic spaces in autonomous institutions and the identities they enable. It situates this exploration in the undergraduate General English classrooms and works with the uses of differing printed-literary and audio-visual media. It also attempts to show how both writing as text and film as text have equal value in undergraduate classrooms. Films, it is proposed, can be more than supplementary/ complementary texts to the much more conventional written-printed ones. They can and ought to occupy an equally privileged position in the teaching-learning process because they provide possibilities for critical understanding and engagement inside the classroom space. It is also argued that films have serious academic and learning potential than is often presumed to be. The article employs for its analysis reports of reception of films within a pedagogic space from student-respondents. In the process of the analysis, the article seeks to construe how classrooms become pedagogic spaces for identity constructions. By way of conclusion, the article comments on the various ways in which films as texts shape critical thinking and self-critique.
Ecotourism and Environmental Sustainability- An Evaluative Study on Kuruva Island in Wayanad, Kerala
Authors: T A Binoy
Published: August 2019

Ecotourism must be understood in the perspective of travelling to natural areas with an intention to study about the flora and fauna of the destination (Lascurain, 1987) (Joshi, 2011). Ecotourism is a nature based tourism activity aimed at environmental education coupled with enjoyment and entertainment.
A Study on Destination Image of Kerala as an Ayurvedic Health Care Destination
Authors: V T Bindu , Swain Sampad Kumar
Published: August 2019

Travel and health are complimentary to each other. Recently there is a demand for stress relieving holidays as people preferred to go for particular holiday destinations where their health was also looked after and where they could rejuvenate themselves. Kerala identified this need and projected itself as a healthcare destination .The Present study concentrates mainly on Kerala‟s holistic healthcare system-Ayurveda. Ayurveda plays a major role in Kerala‟s round the year tourism.  The study is based on the fact that the growth in the health tourism definitely provides sustainable benefits to the Kerala tourism market. Destination image is generally considered as an important attribute in successful destination marketing. This paper aims to identify various destination features which contribute to build a positive destination image about Kerala as a healthcare destination and to understand the relationship between tourist perception and satisfaction. The study explores the destination image enhancement opportunities that exist between the tourist preferences and satisfaction in the desired healthcare service delivery.
Language Standardization of Modern English Language: Errors or Communicative Innovations?
Authors: Николаева Н. , Nikolaeva N.
Published: August 2019

The article discusses the current changing of linguistic norms in English as a lingua franca of global communication nowadays. It aims at both determining the causes of language deviations and analyzing language errors as well as their impact on the effectiveness of the English language communication. Based on the analysis of abundant empirical material, we prove that language innovations are caused by the immanent structural, functional, and pragmatic variability / instability of the English language; they are also associated with cognitive and sociocultural evolution. The research methodology includes: a corpus-based analysis of speech errors; interpretative, context and discourse analyses of the sources of language errors, as well as their distribution, adaptation, habitualization, legitimization, and regulation. We discuss the degree of influence of these processes on native and non-native speakers. Special attention is paid to multilingual interference and the Internet language creation. The findings show that it is impossible to separate language errors from language innovations today. Such conventional governing principles of error normalization as credibility, codification, and approval are still playing an important role while the demographic and geographic principles are losing their significance. The Internet communication often proliferates error normalization processes, which result in evaluating (accepting or rejecting) any innovation according to the principle of “virtual validity”. In conclusion, the English language status as a language of the international communication significantly transforms its norms, rules, and traditions. We think, this will not worsen it, but allow people of different nationalities to communicate in English more effective using their “English variant”, which is the most adapted one to their cognitive, functional and pragmatic needs.
6th, 7th and 8th Grade Students’ Misconceptions about the Order of Operations
Authors: Tabak Sanem
Published: August 2019

The aim of this research is to determine the misconceptions among 6th, 7th and 8th grade students about the order of operations in line with arithmetic expressions and posing and solving problems related to arithmetic expressions. The research has a mixed-method research design with concurrent-triangulation design. The study group for the research comprised a total of 240 students with 78 from 6th grade, 80 from 7th grade and 82 from 8th grade chosen with the simple random sampling method from schools located in a city in the Eastern Black Sea Region in Turkey. The research used a two-tier diagnostic test developed by the researcher to determine the misconceptions of students. According to the results of the research, it was determined that 6th, 7th  and 8th grade students performed arithmetic expressions from left to right without paying attention to order of operations, stated that only operations in brackets need to be performed first in terms of order of operations, did not pay attention to order of operation when writing or solving an arithmetic expression equal to a given number, and that students had difficulty posing a problem sentence involving arithmetic expressions and requiring order of operations.
Potential for Blocking Advancement: Teaching Surveys for Student Evaluation of Lecturers
Authors: Eckhaus Eyal , Davidovitch Nitza
Published: August 2019

In the current study we examined the relationships between student evaluations of lecturers (teaching surveys) and faculty members' perceptions of these surveys as capable of blocking and limiting their professional advancement. Faculty members are judged and evaluated by academic authorities for their academic performance in research and teaching. 178 questionnaires were collected from the faculty of several academic institutions. We employ a mix method analysis, and form a model that reflects the factors perceived by faculty members as having the potential to block their professional advancement in academia. The research findings show that lecturers are of the opinion that teaching load has a detrimental effect on students' evaluations in the surveys. Lecturers at the beginning of their academic life, those in lower ranks: senior teacher and senior lecturer, address the negative aspects of the surveys more than others. The research findings indicate that although more hours are taught in colleges than at universities, it is harder to receive positive survey ratings at colleges. Moreover, since in Israeli academia research is still the main criterion for promotion – faculty members born in Israel were found to teaching less than those born elsewhere. Hence, faculty members think that student surveys are destructive and entail risks for their professional advancement. Assuming that students' voice and opinions on teaching are important – how can a balance be achieved between the research achievements of faculty members and student satisfaction?
Antibacterial and photocatalytic performance of Silver orthophosphate/Hydroxyapatite composite
Authors: El yacoubi Ahmed , Chafik El idrissi Brahim , Rkhaila Amine , Sallek Brahim
Published: August 2019

The present work reports the synthesis of pure hydroxyapatite and HAp supported Ag3PO4 (Ag3PO4/HAp composites) with varying amounts of silver ions Ag+ with a facile in-situ ion exchange method. XRD results of Ag3PO4/HAp composite reveal the peaks characteristic of pure HAp with additional peaks of silver ions which suggest the deposit of silver particles on the support surface (HAp). The nano-composites Ag3PO4/HAp samples show good adsorption and improved photocatalytic activities in methylene blue MB degradation (more than 70%). Antibacterial study of Ag3PO4/HAp nano-composites showed that the HAp dried at 90°C possesses some antibacterial activity against Escherichia coli and Staphylococcus aureus bacteria. Also, compared to HAp sample, deposition of Ag3PO4 nanoparticles on HAp surface improves the antibacterial performance of the composites.
Effect of bismuth and bore content in glass system inhibitor on the corrosion behavior of mild steel in 1M hydrochloric acid solution
Authors: Elbadaoui Azeddine , Mouhsine Galai , Ferraa Soumya , Barebita Hanane , Cherkaoui Mohammed Cherkaoui , Guedira Taoufiq
Published: August 2019

The influence of (0.90-x) Bi2O3-xB2O3-0.10 (Ta2O5-Nb2O5) on the corrosion behavior of mild steel in 1MÂ hydrochloric acid was studied. Electrochemical polarization and impedance spectroscopic methods measurements were used. The inhibition efficiency increases with S1 concentration to reach 79% at 150 ppm. Polarization curves show that our inhibitors. S1 is a cathodic inhibitor type. The increase in temperature leads to a decrease in the inhibition efficiency of the used inhibitor. The thermodynamic study showed that the film was formed at the steel surface by physisorption in the presence of inhibitor. Moreover, in this study, the results showed that the inhibition efficiencies depend on the B2O3 andBi2O3 content in the glass. it is observed that the value at 50% of B2O3 in the glass provided better protection than the other content.
GC/MS Analysis and Antibacterial Activity of the Essential Oil of Moroccan Tetraclinis articulata (Vahl) Masters
Authors: Rabib Halima , Zougagh Sophia , Hsain Mohamed , Badri Wadi , Koussa Tayeb
Published: August 2019

The quality and the variability of the chemical composition and antimicrobial properties of essentials oils isolated from Tetraclinis articulata (Vahl) leaves, which were studied from two different regions that are ecologically various. The average yield of essential oil is 0,56 % for the Ras Elma Tazekka region (mountain) and 0,36% for the Debdou region (plain). An analysis made by GC and GC/ MS identified 22 components in Tetraclinis articulata leaves essential oil in the mountain area and 29 components in the plain area. These major components represent the variability of quantity. The percentages following respectively by the two areas are: Bornyl acetate (34,84%; 32,55%), α-Pinene (11,41%; 18,83%), Camphor (11,24 %; 11,31%), Limonene (11,94 %; 8%) and Borneol (8,35%; 7,79%). The antimicrobial activity of T. articulata essential oil was tested against clinical isolates of Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli which has been inhibited from the 50μg / mL concentration for the Debdou region (Plain) and 25μg / mL for that of the Ras Elma Tazekka region (Mountain).
Applying Response Surface Methodology to optimize the decarbonization process of Timahdit oil shale
Authors: Makouki Laila , Tarbaoui Meriem , Glissi Samia , Mansouri Said , Hannache Hassan , Oumam Mina
Published: August 2019

The present article aims to optimize the decarbonization of Timahdit oil shale layer Y by removing carbonates from the raw rock using acetic acid. The response surface methodology â€œcentral compositeÂ design (CCD)â€ has been used as a method of optimization to study the 3 factors of the process. The factors studied are the concentration of the acid, the processing time, and the ratio (liquid/solid). The optimal conditions with 68.17% of residue rate are obtained with 2 mol/l as concentration, 120 min as a time of treatment and 10.02 for the ratio.The raw (Y) and optimized materials (YO) were characterized by Scanning Electron MicroscopyÂ (SEM), X-ray fluorescence (XRF) and X-rayÂ diffractionÂ (XRD). The results showed that the acetic acid used to remove carbonates affects the chemical composition and the texture evolution of the residues.
Cationic distribution in the new Nd2CaSnO6 perovskite type phase
Authors: Boudar Noureddine , Aatiq Abderrahim , Bellefqih Hajar , Marchoud Asmaa , Manoun Bouchaib , Orayech Brahim
Published: August 2019

The new Nd2CaSnO6 double perovskite oxide has been synthesized in polycrystalline form by a conventional solid-state reactions process at 1300°C in air atmosphere. Structure refinement, realized by Rietveld analysis using the X-ray powder diffraction (XRD) data, shows that the compound crystallizes in monoclinic symmetry with P21/n space group and Z = 2. Obtained unit-cell parameters are: a = 5.6585(1) Å, b = 5.9254(1) Å, c = 8.1883(2) Å,  = 90.116(1) ° and V = 274.5(1) Å3 . The cationic distribution over the A- and B-sites of this perovskite structure can be illustrated by the [Nd1.90Ca0.10]A[Nd0.10Ca0.90]B’[Sn1.00]B’’O6 crystallographic formula. The monoclinic structural distortion involves long-range ordering between Sn4+ (in 2c site) and a random mixture (0.90Ca2+; 0.10Nd3+) (in 2d site) all at the B-perovskite sites.
Changes of Physicochemical composition of Moroccan bovine’s milk along the years
Authors: Chrif Marouane , El hourch Abderrahim , Chouni Selma , Bouyahya Abdelhakim , El abidi Abdallah
Published: August 2019

Milk production in Morocco has increased in recent years to meet local demand. For this reason, this work was carried out in order to study the evolution of the main factors of physicochemical variation of fresh mixture milk of the cow harvested in Moroccan farms and cooperatives, by comparing them with the results of research carried out in Morocco during the last century. 52 samples were taken to represent the different periods of the year. The results showed that the physicochemical properties studied were not significantly improved over the years. Thus, the protein content (3.05%) decreased concerning the fat content (3.57%) in recent decades. This change is mainly related to lactation, cow diet and climate change. Overall, these results could help further studies aimed at controlling the physicochemical properties of milk, taking into account the factors mentioned.
Synthesis of some new 5-amino-3-(substituted-amino)-6-(fluoro/ nitro)aryl-1,2,4-triazine derivatives as lamotrigine analogs and their evaluation in vitro as antibacterial agents
Authors: Alharbi Abdulrahman Salim , Alshammari Nawaa Ali
Published: August 2019

Some new fluorine-substituted 3,5-disubstituted amino-1,2,4-triazines have been obtained from aryl-amination of 2,2,2-trifluoro-N-[2-(5-hydroxy-3-thioxo-2,3-dihydro-1,2,4-triazin-6-yl)-4-nitrophenyl] acetamide followed by ammonolysis to produce N-(2-(5-amino-3-(arylamino)-1,2,4-triazin-6-yl)-4-nitrophenyl)-2,2,2-trifluoroacetamides which reacted with N-phenylthiourea. The structures of products were deduced from their elemental analysis and spectral measurements. The new lamotrigine analogs were evaluated in vitro as antibacterial. Interestingly, some compounds showed interesting activity against the Bacillus subtilis, Streptococcus faecalis, Micrococcus luteus, and Staphylococcus aureus bacteria.
Juazeiro iconográfico: da linguagem visual aos ícones da cidade
Authors: Oliveira Elane Abreu de , Oliveira Joedson , Duarte Luan , Oliveira Romênia , Souza Thamyres
Published: August 2019

Este trabalho discute a capacidade comunicativa do visual, entendendo-o como campo de conhecimento permeado por signos e mensagens socialmente praticados. Em Juazeiro do Norte – CE, a marca da Prefeitura é exemplo de uma prática visual comunicativa desencadeada por sua composição com elementos icônicos da cidade. Com o objetivo de analisar a linguagem visual e a representatividade dos lugares utilizados, foi feita uma pesquisa exploratória de marcas similares a de Juazeiro do Norte e uma análise dos elementos que compõem a marca da cidade. A reunião dos signos visuais apresentados ressalta que a representação da cidade está fincada principalmente em ícones da arquitetura e da religiosidade, o que comunica o valor destas visualidades para a imagem urbana.
OCORRÊNCIA, FREQUÊNCIA E DANOS DAS PRECIPITAÇÕES DE GRANIZO NA REGIÃO METROPOLITANA DE CURITIBA
Authors: Caldana Nathan Felipe da Silva , Caramori Paulo Henrique , Costa Angela Beatriz Ferreira da , Silva Glauco Marighella Ferreira da
Published: August 2019

As condições de tempo e clima são essenciais para a agricultura e o desenvolvimento da sociedade, entretanto, sua dinâmica pouco compreendida pode comprometer algumas atividades humanas. A precipitação de granizo, um evento extremo caracterizado por precipitação de água em estado sólido, tem alta capacidade destrutiva tanto no meio rural quanto no urbano, gerando transtornos e prejuízos frequentes. A Região Metropolitana de Curitiba (RMC) possui um grande contingente populacional com grande vulnerabilidade a eventos extremos meteorológicos, sendo necessários estudos que auxiliem para o planejamento na região. Dessa forma objetivou-se neste trabalho identificar a formação, frequência, ocorrência e os danos de precipitações de granizo na RMC. Para isso, utilizou-se dados disponibilizados pelo Instituto Agronômico do Paraná (IAPAR), Sistema Meteorológico do Paraná (SIMEPAR), Defesa Civil do Paraná, jornais publicados e cartas sinóticas disponibilizas pelo Instituto Nacional de Pesquisas Espaciais. O recorte temporal utilizado foi de 1986 a 2017. Identificou-se que o eixo de Campo Largo a São José dos Pinhais é o mais vulnerável e com maior frequência de granizo, chegando a registrar 4 precipitações de granizo por ano. A estação de primavera e o mês de setembro registraram maior número de eventos e sua principal formação foi por meio dos sistemas convectivos
A DIFERENÇA SALARIAL NAS INDÚSTRIAS BRASILEIRAS: DESDOBRAMENTOS NO ESPAÇO GEOGRÁFICO
Authors: Marques Ana Carolina dos Santos , Bragueto Claudio Roberto
Published: August 2019

A indústria tem papel importante na produção do espaço e na geração de riqueza social, compreender suas dinâmicas é importante para entender o arranjo espacial e seus desdobramentos no território. A renda média do pessoal ocupado caracteriza-se como uma destas dinâmicas essenciais para compreensão da organização espacial brasileira, produzindo impactos socioeconômicos na população brasileira. Desta forma, objetiva-se verificar a diferença salarial no setor industrial nas mesorregiões geográficas relevantes, de acordo com a intensidade tecnológica, sendo o recorte temporal os anos de 1995 a 2015. Para tanto, foram realizados levantamentos bibliográficos e do banco de dados do Ministério do Trabalho e Emprego - RAIS, além do mapeamento das mesorregiões geográficas relevantes em termos de pessoal ocupado. Os resultados apontam que o período em questão foi marcado por uma desconcentração concentrada, em que as mesorregiões de maior crescimento e maior número de pessoal ocupado estão localizadas em sua maioria, no Centro-Sul do Brasil e que a desigualdade salarial brasileira é constituída pelas rendas médias menores centralizadas na região Nordeste e pelas remunerações maiores no Centro-Sul do país. Além disso, houve uma queda de renda média generalizada, tanto em termos regionais quanto nos ramos industriais de maior ou menor intensidade tecnológica.
TIPOLOGIAS DO CARSTE E CLASSIFICAÇÕES DE DOLINAS: UMA REVISÃO
Authors: Ferreira Cristiano Fernandes , Uagoda Rogério Elias Soares
Published: August 2019

Neste trabalho de revisão buscou-se inicialmente colecionar as tipologias de classificação do carste utilizadas através do tempo no mundo e algumas de suas aplicações no Brasil. É dado enfoque a questões morfogenéticas responsáveis pelo desenvolvimento de feições cársticas superficiais, fruto de processos nem sempre visíveis que operam em subsuperfície. Os mecanismos de desenvolvimento das dolinas, consideradas feições elementares e diagnósticas do carste, são discutidos principalmente entre processos de dissolução, subsidência e colapsos. É apresentada uma proposta terminológica de classificação genética de dolinas baseada nas principais publicações internacionais sobre o tema. Por fim é discutida também a questão morfológica das depressões cársticas, critério igualmente utilizado para a separação tipológica destas feições.
NADA POLIFONIK TEKS MARXIST ALA KUNTOWIJOYO: PENCARIAN JATI DIRI DARI MARXISME KE ISLAM
Authors: Makin Al
Published: August 2019

This paper presents the way in which Kuntowijoyo searches for an epestimological formulation and critical thinking from Marxits to Islamic tendencies. This effort fills the gap left by some Indonesian readers of Kuntowijoyo’s works who only highlight his Islamic ideas in literature, culture, history, and sociology from which Kuntowijoyo unleashes the idea of prophetic paradigmn to differentiate his thought from secular Western mode of thinking.  This paper also compares Kuntowijoyo’s text to the performance dangdut music of Rhoma Irama to discover the tone and rhytm of polyphone, by which I mean complexity of the text in combining Western and Eastern thoughts. This writing sheds light on the polyphonic tone of Kuntowijoyo’s text and the shifting paradigm of his thought from Marxist to Islamic tendencies.Tulisan ini membahas pergulatan pemikiran Kuntowijoyo dari aliran Marxist menuju arah Islamis. Dalam tulisan ini menyoroti para pembahas di Indonesia yang sering menekankan gagasan islami Kuntowijoyo dalam sastra, budaya, pemikiran sejarah dan sosiologi, terutama gagasan tentang profetiknya dalam bidang-bidang tersebut. Tulisan ini sekaligus membandingkan teks polifonik Kuntowijoyo yang meramu tradisi Marxisme Barat dengan musik dangdut Rhoma Irama sebagai tolak ukur nada dan irama polifonik. Baik musik dangdut ataupun teks Kuntowijoyo menghadirkan berbagai unsur perpaduan Barat dan Timur dan sekaligus mengarah pada pencarian identitas keislaman Kuntowijoyo dan Rhoma Irama. Tulisan ini sekaligus memberi sumbangan baru pada pembacaan teks polifonik dan pergeseran gagasan Kuntowijoyo dari Marxist ke Islami yang tidak mendapatkan porsi cukup dari para pembahas di Indonesia.
PERSEPSI PENYANDANG DISABILITAS DAN STAKEHOLDER UNTUK MEMPROMOSIKAN DAN MENGEMBANGKAN KOMUNITAS INKLUSIF DI DIY DAN ASIA TENGGARA
Authors: Hanjarwati Astri , Suprihatiningrum Jamil , Aminah Siti
Published: August 2019

This research was conducted to investigate the perceptions of persons with disabilities and stakeholders regarding the promotion and development of Friendly and Inclusive Communities in Bantul Regency, DIY and Kendari City, Southeast Sulawesi. The study was designed using transformative mixed-method, with the framework of KIPA (Knowledge, Inclusion, Participation, and Access) as a theoretical framework core. The first step was carried out by an empirical survey through distributing questionnaires to 48 respondents in Bantul Regency and 52 respondents in Kendari City. The results of data analysis from questionnaire contents were processed through descriptive statistics to describe respondents' perceptions quantitatively. Quantitative results are used as a reference in qualitative data collection, namely through in-depth interviews with selected respondents. The results of the study show that both persons with disabilities and stakeholders have a positive perception of the promotion and development of a friendly and inclusive community in their area. Although knowledge about disability, inclusion and the issues that surround it is still limited, but both persons with disabilities and stakeholders claim the need for a Friendly and Inclusive Community to be realized. Repondents of persons with disabilities also added that participation and access to development by and for persons with disabilities needs to be improved both in terms of quantity and quality.Penelitian ini dilakukan untuk menginvestigasi persepsi penyandang disabilitas dan stakeholders mengenai promosi dan pengembangan Komunitas Ramah dan Inklusif di Kabupaten Bantul, DIY dan Kota Kendari, Sulawesi Tenggara. Penelitian didesain menggunakan transformative mixed-method, dengan kerangka KIPA (Knowledge, Inclusion, Participation, and Access) sebagai core theoretical framework. Langkah pertama dilakukan dengan survey empiris melalui penyebaran kuesioner kepada 48 responden di Kabupaten Bantul dan 52 responden di Kota Kendari. Hasil analisis data dari isian kuesioner diolah melalui statistik deskriptif untuk menggambarkan persepsi responden secara kuantitatif. Hasil kuantitatif dijadikan sebagai rujukan dalam pengambilan data secara kualitatif, yaitu melalui in-depth interview kepada responden terpilih. Hasil penelitian menunjukkan baik penyandang disabilitas maupun stakeholders memiliki persepsi yang positif terhadap promosi dan pengembangan Komunitas Ramah dan Inklusif di daerah mereka. Meskipun pengetahuan mengenai disabilitas, inklusi dan isu-isu yang melingkupinya masih terbatas, namun baik penyandang disabiltias dan stakeholders mengaku perlunya Komunitas Ramah dan Inklusif untuk diwujudkan. Reponden penyandang disabilitas juga menambahkan bahwa partisipasi dan akses pembangunan oleh dan untuk penyandang disabilitas perlu ditingkatkan baik dari segi kuantitas maupun kualitas.
As mídias sociais e a Ortodontia
Authors: Almeida Marcio
Published: August 2019

Você já parou para pensar quanto tempo passamos conectados na Internet ou nas mídias sociais? O brasileiro é um verdadeiro amante das redes sociais, ultramegaconectado, e cada vez menos dependente do computador para acessar a internet. Esse é o perfil do internauta brasileiro, que, entre outras tendências, segue o movimento global de usar os smartphones para navegar (68% dos brasileiros já usam telefones móveis).
Integração entre a Ortodontia e a Dentística no restabelecimento da estética, oclusão e dimensão vertical em casos complexos de pacientes adultos
Authors: Furquim Laurindo Zanco
Published: August 2019

"Paciente adulto, 68 anos de idade, com mordida cruzada do lado direito, agravada pelo trespasse anterior dos incisivos, também cruzados. Relatou que sempre recusou o tratamento ortodôntico devido ao receio da expansão rápida da maxila assistida cirurgicamente — a qual foi a única opção oferecida em todas as oportunidades que ele procurou tratamento ortodôntico." [...]
Reabsorção cervical externa na Ortodontia: observações sobre a causa, distribuição e diferenciação
Authors: Consolaro Alberto
Published: August 2019

As reabsorções dentárias associadas ao tratamento ortodôntico são as reabsorções apicais externas inflamatórias; as demais têm outras causas relacionadas e são simultâneas e/ou coincidentes. No entanto, em pleno andamento do tratamento ortodôntico, a reabsorção cervical externa pode estar presente em duas outras situações que podem ser associadas ao tratamento em si, apesar de induzidas por procedimentos cirúrgicos solicitados ao cirurgião bucomaxilofacial: 1) o preparo cirúrgico para tracionamento ortodôntico, pela manipulação do folículo pericoronário; e 2) a exodontia de dentes íntegros como parte do planejamento e tratamento ortodôntico. A reabsorção cervical externa é comum e, muitas vezes, confundida com a abfração ou cárie de colo. Ela é recoberta ou “escondida” por tecido gengival normal e até sutilmente inflamado, enquanto a cárie de colo e a abfração se encontram expostas nas superfícies coronárias e voltadas diretamente para a cavidade bucal.
Some studies on Lorentz transformation matrix in non-cartesian co-ordinate system
Authors: Das Mukul Chandra , Misra Rampada
Published: August 2019

The Lorentz matrices for transformation of co-ordinates in Cartesian system are presented for the cases when the relative velocity between two reference frames is along X , Y and Z axes. The general form of the matrix for transformation of co-ordinates from unprimed to primed frame has been deduced in case of Cartesian co-ordinate system with the help of the above matrices. This matrix has not been transformed to the cases of cylindrical and spherical polar co-ordinates due to the fact that the calculations are cumbersome and lengthy. Hence, considering the relative velocity between two frames along a co-ordinate axis the transformation matrix has been found out for cylindrical and spherical co-ordinates.
Ridesharing
Authors: Pan James J. , Li Guoliang , Hu Juntao
Published: August 2019

Ridesharing is becoming a popular mode of transportation with profound effects on the industry. Recent algorithms for vehicle-to-customer matching have been developed; yet cross-study evaluations of their performance and applicability to real-world ridesharing are lacking. Evaluation is complicated by the online and real-time nature of the ridesharing problem. In this paper, we develop a simulator for evaluating ridesharing algorithms, and we provide a set of benchmarks to test a wide range of scenarios encountered in the real world. These scenarios include different road networks, different numbers of vehicles, larger scales of customer requests, and others. We apply the benchmarks to several state-of-the-art search and join based ridesharing algorithms to demonstrate the usefulness of the simulator and the benchmarks. We find quickly-computable heuristics outperforming other more complex methods, primarily due to faster computation speed. Our work points the direction for designing and evaluating future ridesharing algorithms.
Hyper dimension shuffle
Authors: Qiao Shi , Nicoara Adrian , Sun Jin , Friedman Marc , Patel Hiren , Ekanayake Jaliya
Published: August 2019

In distributed query processing, data shuffle is one of the most costly operations. We examined scaling limitations to data shuffle that current systems and the research literature do not solve. As the number of input and output partitions increases, naïve shuffling will result in high
fan-out
and
fan-in.
There are practical limits to
fan-out,
as a consequence of limits on memory buffers, network ports and I/O handles. There are practical limits to
fan-in
because it multiplies the communication errors due to faults in commodity clusters impeding progress. Existing solutions that limit
fan-out
and
fan-in
do so at the cost of scaling quadratically in the number of nodes in the data flow graph. This dominates the costs of shuffling large datasets.

We propose a novel algorithm called Hyper Dimension Shuffle that we have introduced in production in SCOPE, Microsoft's internal big data analytics system. Hyper Dimension Shuffle is inspired by the divide and conquer concept, and utilizes a recursive partitioner with intermediate aggregations. It yields
quasilinear
complexity of the shuffling graph with tight guarantees on
fan-out
and
fan-in.
We demonstrate how it avoids the shuffling graph blow-up of previous algorithms to shuffle at petabyte-scale efficiently on both synthetic benchmarks and real applications.
Real-time distributed co-movement pattern detection on streaming trajectories
Authors: Chen Lu , Gao Yunjun , Fang Ziquan , Miao Xiaoye , Jensen Christian S. , Guo Chenjuan
Published: August 2019

With the widespread deployment of mobile devices with positioning capabilities, increasingly massive volumes of trajectory data are being collected that capture the movements of people and vehicles. This data enables co-movement pattern detection, which is important in applications such as trajectory compression and future-movement prediction. Existing co-movement pattern detection studies generally consider historical data and thus propose offline algorithms. However, applications such as future movement prediction need real-time processing over streaming trajectories. Thus, we investigate real-time distributed co-movement pattern detection over streaming trajectories.

Existing off-line methods assume that all data is available when the processing starts. Nevertheless, in a streaming setting, unbounded data arrives in real time, making pattern detection challenging. To this end, we propose a framework based on Apache Flink, which is designed for efficient distributed streaming data processing. The framework encompasses two phases: clustering and pattern enumeration. To accelerate the clustering, we use a range join based on two-layer indexing, and provide techniques that eliminate unnecessary verifications. To perform pattern enumeration efficiently, we present two methods FBA and VBA that utilize id-based partitioning. When coupled with bit compression and candidate-based enumeration techniques, we reduce the enumeration cost from exponential to linear. Extensive experiments offer insight into the efficiency of the proposed framework and its constituent techniques compared with existing methods.
Development of a Thermo-Hydro-Mechanical Device for Wood Densification Adaptable to Universal Testing Machines and Its Evaluation in a Tropical Species
Authors: Tenorio Carolina , Moya Roger
Published: August 2019

There is considerable interest in the development of thermo-hydro-mechanical (THM) treatments to increase the density of low-density woods. However, the development of processes for improving the properties of low-density woods in regions with lower investments in investigations and development, such as tropical areas, is often limited by the equipment and infrastructure constraints. The aim of this work is to outline the development and construction of an inexpensive THM densification device (THM device) that controls the application of heat, load, and steam, by adapting an accessory to a 60-Mg universal testing machine (UTM). The THM device was evaluated using the Vochysia guatemalensis wood (tropical species). The inexpensive densification THM device uses steaming, temperature, and compression and can be adaptable to a 60-Mg-capacity UTM. It also allowed us to successfully conduct the densification process on 20 by 70 by 300 mm wood samples of a low-density tropical species. However, there were some drawbacks discovered: for example, the steam application, pressure, and temperatures were controlled independently, which was not convenient. It would be more convenient to concentrate them in a single control unit. Additionally, a high variation was observed in the compression and stabilization thickness.
Selective Coronary Angiography Following Cardiac Arrest
Authors: Eshcol Jayasheel O. , Chhatriwalla Adnan K.
Published: August 2019

Sudden cardiac arrest is a major cause of death predominantly caused by ventricular tachyarrhythmia in patients with coronary artery disease. Despite advancements in resuscitation care, the rate of survival after cardiac arrest remains low. There is a growing body of observational data suggesting early coronary angiography reduces delay to revascularization and may improve outcomes. Most survivors present comatose, and neurologic outcome is uncertain; therefore it is often challenging to identify patients who will benefit from early coronary angiography. Several variables and risk scores that predict a favorable neurologic outcome have been identified. The rationale and current evidence for early angiography are reviewed, and a suggested approach to the selection of patients is presented.
Monitoring geomagnetic information in the territory of Croatia
Authors: Brkić Mario
Published: August 2019

In orientation and navigation using compass, reliable map’s marginal information of Earth’s magnetic field declination and its annual variation, namely geomagnetic information (GI), is crucial. Monitoring geomagnetic information means observing declination and its annual variation and checking the reliability of the actual GI model. A typical way of monitoring GI across a national territory involves conducting periodic geomagnetic network surveys to assess and update the model. The objective of the paper was to investigate improving the GI model reliability when an earlier model’s error was raised to standard accuracy, and repeat station network surveys were not yet completed. A series of processing steps in modelling were revised to preserve the original data reliability. The partial 2008.5, 2009.5 and 2010.5 declination solutions were directly reduced to epoch 2015.0, and then to 2016.0, using the IGRF-12 model. The next step was to use 2016 and 2017 quiet daily declination means to estimate corresponding annual variations at surrounding observatories and repeat stations. Normal declination annual variation models were then built for further reductions to epoch 2017.0, and 2018.0, and for forward extrapolations. The quiet days observatory data were analysed to estimate the effect of the input time series length and linear extrapolated time span on forward extrapolation error. Thus, the reliability decline of the initial GI model slowed down in the sequence of models presented. The final GI2018v2 model, valid for 2018.0–2019.0, proved reliable in comparison to the repeat station declination observations of 2018.
Discourse Space of the Linguocultural Character Type “Professor”
Authors: Sinelnikova Lara
Published: August 2019

The article offers an analysis of the linguocultural character type professor taking into consideration both traditional set of signs and those transformations that indicate accumulation of evolutionary changes. The methodological base for the systematic description were the achievements of such areas of scientific knowledge as personology, linguopersonology and discourseology. The linguocultural character type (LCCT) is a generalised image of persons, whose behaviour and value orientations influence culture, language and show social originality of the society. The peculiarity of the studied linguocultural character type is in its interrelation with the linguocultural character types intellectual and teacher as well as in the fact of the traditional connection with the concept elite. The exposure of such kind of multidimensional relations allowed to focus attention on the qualities of the LCCT professor that ensure its relative self-sufficiency. The sign of elitism and belonging to the intellectuals of the LCCT professor is asserted by the high social status recognised by the society, which is based on professionalism and compliance with moral principles. The axiological generality of the LCCT professor and teacher is ensured by the peculiarities of the modern pedagogical discourse with its typical image settings. One of the main features of the image of a professor is its belonging to the elite language person. The transformational processes in the contents of the LCCT professor are connected with the globalisation: including the international dimension in the evaluation of the professional activity, complication of the language environment, marketisation of the university sphere.
Ковтун, Н. В. (ed.), Кризис литературоцентризма. Утрата идентичности vs. новые возможности
Authors: Herlth Jens
Published: August 2019

КОВТУН, Н. В. (ED.), 2014. КРИЗИС ЛИТЕРАТУРОЦЕНТРИЗМА. УТРАТА ИДЕНТИЧНОСТИ VS. НОВЫЕ ВОЗМОЖНОСТИ. Москва: Флинта. ISBN: 978-5-9765-1856-8.
Biskupski, Mieczysław B. B., 2011. Nieznana wojna Hollywood przeciwko Polsce 1939-1945
Authors: Mazurkiewicz Michał
Published: August 2019

BISKUPSKI, Mieczysław B. B., 2011. Nieznana wojna Hollywood przeciwko Polsce 1939-1945. Warszawa: Fijorr Publishing. pp. 390. ISBN 978-83- 89812-77-0.