bluuebunny/crossref_metadata_2025 huggingface dataset:
UPAYA GURU PENDIDIKAN AGAMA ISLAM DALAM PEMBENTUKAN KARAKTER JUJUR DAN KARAKTER TANGGUNG JAWAB SISWA
Authors: Chahnia Juwi , Kustati Martin , Amelia Rizki
Published: February 2024

Penelitian ini dilatar belakangi dengan adanya masalah-masalah karakter pada siswa yaitu siswa yang sering bolos, alfa, tidak mengerjakan tugas, bermain-main saat jam pelajaran berlangsung, mencontoh saat ujian dan mengerjakan tugas, berbohong ketika ditanyai informasi oleh guru dan melanggar aturan sekolah lainnya ini, merupakan masalah yang terjadi pada karakter siswa yaitu pada karakter siswa yaitu pada karakter jujur dan tanggung jawab. Tujuan dari penelitian ini yaitu untuk mengetahui upaya yang dilakukan guru PAI dalam pembentukan karakter jujur dan tanggung jawab pada siswa, sekaligus juga mengetahui kendala-kendala yang dihadapi guru PAI dalam membentuk karakter ini. Adapun jenis penelitian ini yaitu menggunakan metode field and research dengan pendekatan kualitatif deskriptif. Teknik pengumpulan data yaitu menggunakan teknik observasi, wawancara dan dokumentasi. Teknik analisis data yang digunakan yaitu dengan cara reduksi data, teknik penyajian data dan teknik pengambilan kesimpulan. Hasil dari penelitian ini yaitu upaya yang dilakukan guru PAI dalam pembentukan karakter jujur dan tanggung jawab yaitu dengan cara memberikan perhatian dan motivasi kepada siswa tentang pentingnya pembiasaan berprilaku jujur dan bertanggung jawab, metode keteladanan,menerapkan metode reward dan punishment,mengimplementasikan pembelajaran PAI dalam mewujudkan pembentukan karakter jujur dan tanggung jawab,meningkatkan kerja sama antara guru dan orang tua. Adapun kendala-kendala yang dihadapi yaitufaktor lingkungan, termasuk lingkungan keluarga ataupun lingkungan teman sebaya, kurangnya kesadaran siswa akan pentingnya membiasan sikap jujur dan bertanggung jawab, dan guru kurang memperhatikan perkembangan karakter siswa
EFEK MATERIAL CARBON TERHADAP SENSITIVE SENSOR CONTROL
Authors: Muhammad Yusuf Nurfani
Published: February 2024

Touchscreen is a technology used in the process of user selection access to control a function. In general, the touchscreen uses a cover that is used to cover the electrical function. The process of making cover control generally uses printing media with black INK material where in nature there are many chemical ingredients. In this study, an analysis of the nature of carbon will be carried out on the sensitivity of the control sensor in receiving a command. The results of the analysis found that the carbon material in INK affects the sensitivity quality of a sensor control function by 80% failure, so it is recommended for the forming agent of the base cover.
Implementasi Aplikasi Toko Creative Card Berbasis Website Menggunakan Metode Waterfall
Authors: Yusuf Aprianto
Published: February 2024

The development of technology and the internet has triggered a significant transformation in consumer behavior, especially in the context of electronic commerce. This research aims to address growing market needs by developing a web-based online sticker shop application. This application is designed to provide convenience in the process of selling and purchasing stickers, optimize user experience, and increase product accessibility via online platforms. The development method used in this research involves the application of web technologies such as HTML, CSS, JavaScript, and PHP. This approach allows building systems in a structured and organized manner, with a focus on features that support intuitive user interaction. Some of the key features implemented include informative product pages, an efficient shopping cart system, and transaction history to provide transparency and order tracking for consumers. The result of this research is an online sticker shop application that not only makes the sales process easier for sellers, but also provides a comfortable online shopping environment for buyers. It is hoped that this application can increase efficiency in sales management, increase the competitiveness of the sticker business, and make a positive contribution to the growth of the e-commerce industry. As an innovative solution, this application is expected to be able to keep up with market trends and provide a satisfying online shopping experience for users.
APPLICATION OF A TWO-DIMENSIONAL MATRIX FOR DETERMINING STRATEGIC POSITIONING OF GARMENT COMPANIES IN UKRAINE
Authors: Radionova Nataliia , Tarasenko Irina , Khmurova Viktoriia
Published: February 2024

The article presents the results of a study of the strategic positioning of enterprises using a two-dimensional matrix. The main goal of the study is to form a two-dimensional matrix for effectively assessing the strategic position of domestic enterprises in the garment industry. A correctly developed and effectively implemented positioning strategy can provide not only a significant competitive advantage for an enterprise but also form its optimal strategic vector of development.In modern market conditions checking the relevance of the strategic position used is becoming increasingly important for enterprises, which determines the relevance of the research topic.The results of the analysis of modern trends and problems in Ukrainian, conducted in previous studies, garment companies provided an opportunity to determine as strategic variables for companies of the garment industry the consumer value of products (as an external market factor of competitiveness) and the costs of production and sale of products (as a combination of internal and external factors of the formation of a competitive advantage in terms of price). The specified indicators were proposed for the construction of the axes of the strategic positioning matrix, which was tested at six Ukrainian garment companies that produce the same type of products and operate in the same market segmentThe scientific novelty: the proposed approach represents the toolkit for substantiating the direction of strategic development of garment enterprises using the matrix method, in the coordinate system: "consumer value of products" and "enterprise costs", which, unlike the existing ones, allows us to determine topological zones and to choose from the set of alternative strategies for the development of a garment enterprise, the most optimal.The results of the conducted research can have applied value for the heads of garment and other manufacturing enterprises from the standpoint of improving the management of the strategic development of an enterprise.
THE CRYPTOCURRENCY ASSETS MARKET IN THE CONDITIONS OF MILITARY AGGRESSION
Authors: Volosovych Svitlana , Nezhyva Mariia , Vasylenko Antonina , Morozova Liudmyla , Napadovskyi Іhor
Published: February 2024

The Russian-Ukrainian war transformed the needs of consumers of financial services, both in Ukraine and abroad. On the one hand, the civilian population and the Armed Forces of Ukraine needed immediate help from the international community. On the other hand, individual and institutional investors were concerned about threats to traditional financial investments. The purpose of the article is to identify the priority directions for the development of the cryptocurrency asset market against the background of the Russian-Ukrainian war. The article presents an analysis of the cryptocurrency asset market with an emphasis on its structural changes in the conditions of the Russian-Ukrainian war. In the study, a survey was conducted to find out the impact of the war on the Ukrainian cryptocurrency market. The analysis of the survey results substantiates the hypothesis about the impact of increased hacking attacks by pro-Russian forces and missile attacks on the functioning of the cryptocurrency market in Ukraine. It has been confirmed that investments and payments are promising segments of the cryptocurrency market in Ukraine, in which, the most interested users and potential users of cryptocurrency are. Based on the received data, the weaknesses and strengths of the functioning of the cryptocurrency market in the conditions of war were identified. Threats and opportunities for the development of the cryptocurrency market against the background of Russian armed aggression are substantiated. The conducted research made it possible to formulate scenarios for the development of the cryptocurrency asset market in Ukraine in war conditions and the conditions for their implementation.
Chemsex
Authors: ANORO PREMINGER MANEL
Published: February 2024

Caso clínico
–Hola doc, venía a chequearme el VIH.

Era la tercera vez que Samuel venía a chequearse el VIH en los últimos 6 meses. Llegó de Colombia hacía un par de años y trabajaba de teleoperador. Tenía una habitación alquilada y se acercaba poco al centro de Atención Primaria (CAP).

–Me parece bien, Samuel, pero cuéntame, ¿por qué quieres hacerte este chequeo? ¿Te preocupa algo?

Le costó arrancar, pero cuando lo hizo, me contó el motivo de la petición. Samuel era el primer paciente que me hablaba de chemsex.
Chitosan-TPP microcapsules for controlled drug release
Authors: Pérez-Pacheco Yaridé , Alimandi Tiziano , Tylkowski Bartosz , Sisteré Miquel , García-Valls Ricard
Published: February 2024

Production of chitosan/sodium tripolyphosphate (CS/TPP) microcapsules via spray drying involves atomizing an emulsion containing CS, TPP, acetic acid (AcOH), and folic acid (FA) into fine droplets exposed to high-temperature, low-pressure gas flow. Solvent evaporation within the drying chamber leads to solid particle formation. Spray drying is valuable for creating solid CS/TPP microcapsules. Precise equipment parameter adjustments, like inlet temperature and gas flow rate, enable the study of microcapsule morphology, size, and properties. This adaptability allows for customization to specific pH dissolution ranges. The production method's impact on CS/TPP microcapsules was studied by modifying spray drier parameters, including inlet temperature and aspirator pressure, to enhance understanding of their behavior in solution under varied production conditions.

In chitosan delivery systems, various approaches can encapsulate drug agents like folic acid, an analog to the cancer treatment drug methotrexate. Agents can be added to the chitosan solution pre-crosslinking, incorporated into gelation-inducing agents pre-mixing with chitosan, or included in the crosslinking mixture. Experiments were conducted to assess CS/TPP microcapsules' behavior when encapsulating agents like folic acid. Release profiles were analyzed to understand their drug delivery capabilities and potential as controlled release carriers.
The Financial Impact of Professional Discipline on Clinicians: A Case for Preventive Education
Authors: Kaye Alan , O’Quin Collyn , Koontz Colby , Moore Peyton , Ahmadzadeh Shahab , Shekoohi Sahar , Leiser Leia , Cornett Elyse , Chou Yen
Published: February 2024

Regulatory organizations, such as medical licensing boards and private healthcare organizations, evaluate clinicians for lapses in professionalism involving ethics, record keeping, prescribing, and civic duties. Disciplinary action against these clinicians consists of direct penalties, loss of license or credentials, probation of practices, and reputational damage. Specialized remedial education courses often are one of the numerous stages required for a physician to regain good standing with their regulating agency. Many clinicians enrolled in such courses state that the total financial impact of disciplinary action against them is significant. This 2021 study analyzed the financial impact of professional discipline on clinicians who enrolled in a course provided by a large organization specializing in providing remedial CME on various professionalism-focused topics to satisfy disciplinary and regulatory actions. Of the 195 participants, approximately 157 participants completed the questionnaire. Using these data, we have developed hypotheses and recommendations for enhancing education or training focused on topics of professionalism to reduce the need for formal discipline at the outset. Our research shows that disciplinary action has a significant financial and emotional impact on clinicians and that preventative education, or education or training focused on topics of professionalism, can be an important tool to limit the need for disciplinary action.
Os reflexos da parentalidade socioafetiva com implicação aos avós: a ausência do reconhecimento da socioafetividade avoenga
Authors: Oliveira Grasielle Sampaio , Canhedo Nathalia , Silva Gisele Polidoro da
Published: February 2024

As relações humanas, sejam elas quais forem, partem de um vínculo em comum: o afeto. Esse vínculo, por muitas vezes, gera uma nova entidade familiar, podendo ser ela biológica ou afetiva. Pelo fato de ser uma ciência social que é dinâmica, o Direito atual viu a necessidade de reconhecer novas configurações familiares que já existiam de fato mas ainda não haviam sido objeto de estudo do Direito. Dentre esses novos modelos, destaca-se as relações familiares originadas apenas por vínculos afetivos sendo que estes são reconhecidos pela própria sociedade em que convive como membros de uma mesma família, popularmente conhecidos como “filhos de criação” e, juridicamente, como socioafetividade. Ao colocar a conexão socioafetiva no mesmo nível de importância dos laços sanguíneos através da jurisprudência, de forma que um não sobressaia sobre o outro, inúmeras famílias que viviam sob esse molde passaram a ter visibilidade perante o Direito. Com isso, surgiu uma indagação: se, mesmo com o vácuo normativo, haveria a possibilidade do reconhecimento socioafetivo avoengo? Para responder ao questionamento, foi utilizada a metodologia de pesquisa dedutiva, através de bibliografias, documentos e análise dos Códigos Civis de 1916 e 2002. Chegou-se a conclusão que não há impedimentos expressos para a socioafetividade, pelo contrário, há suporte principiológico que baseia a possibilidade de tal reconhecimento.
IMPACT OF IONIC LIQUID ADMIXTUREON ELECTRORHEOLOGICAL AND TRIBOLOGICALPROPERTIES OF A HYDROCARBON LUBRICATING OIL
Authors: Kałdoński Tomasz Jan , Juda Jarosław , Kałdoński Tadeusz
Published: February 2024

The article describes, the relationship between the generated and fading electrorheological effect and tribologicalproperties of hydrocarbon lubricating oils containing ionic liquid admixture. Two quasi-homogeneousmixtures were obtained as a result of miscibility tests: 1) the GP1 silicon damping oil containning ionic liquidCJ001, i.e. 1-methyl-3-octyloxymethylimidazolium tetrafluoroborate and 2) the PAO6 base polyalphaolefinoil containing ionic liquid CJ008, i.e. trihexyltetradecylphoshonium bis-(tri-fluoromethylsulfonyl)imide. Theconducted ER tests revealed differences between the electrorheological properties of the two mixtures. Afterincreasing the electric field strength to E = 0.3 kVmm–1 the ER effect of both mixtures disappeared. Forthese mixtures tribological tests were carried out on a four ball apparatus. The lubricity parameters of thetested ionic liquids are much better than base oils and the oil mixtures with ionic liquids also showed betterlubricating properties than their base oils.
The role of WNT/β-catenin pathway in cancer and autism
Authors: Candar Furkan , Erbaş Oytun
Published: February 2024

The WNT family is a group of signaling molecules that have been shown to control various developmental processes, including cell specification, proliferation, polarity, and cell migration. Dysregulation of WNT signaling plays a role in developmental defects and tumor formation. The importance of WNT signaling in development and clinical pathologies has been emphasized by studies examining various aspects of WNT signaling. There is data suggesting that WNT signaling hyperactivation leads to the pathogenesis of autism spectrum disorder. In this review, the molecular mechanism of WNT/β‐catenin signal transduction as well as the relationship of WNT/β‐catenin signaling dysregulation with tumor formation and autism are discussed.
Fatal rhino-orbito-cerebral mucormycosis
Authors: Oğuz Mızrakçı Serpil
Published: February 2024

Rhinocerebral mucormycosis is a rare but often fatal invasive fungal infection. It is frequently encountered in immunocompromised hosts such as diabetes mellitus, AIDS, hematological malignancies receiving high-dose chemotherapy, and transplant patients. Rhinocerebral involvement is the most common form. A 62-year-old female patient who was admitted with complaints of redness, swelling, pain, elevated body temperature, closure of the left eye, and high fever was diagnosed with rhino-orbito-cerebral mucormycosis based on physical examination, radiological imaging, histopathological results, and tissue culture. The case of the patient who died despite repeated surgical debridement and antifungal therapy is presented to draw attention to the extremely fatal rhino-orbito-cerebral mucormycosis cases.
COVID-19 in a patient with pre-existing liver disease
Authors: Çevik Banu , Önder Aydın Mehmet , Bombacı Elif , Tolga Saraçoğlu Kemal
Published: February 2024

Although Coronavirus Disease 2019 (COVID-19), the clinical disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is characterized by respiratory symptoms predominantly, the liver is the main actor in the progression of the disease. Liver involvement exhibits various clinical manifestations from asymptomatic elevations of liver function test to severe hepatic decompensation. In cases of underlying liver failure, the clinical presentation may become more dramatic and requires priority in the management. Treatment of these patients is troublesome due to the potential hepatotoxicity of agents used for the COVID-19. Data on COVID-19 patients having pre-existing liver failure conflicts, and whether these patients are more susceptible to the infection remain unclear. However, in patients with advanced chronic liver failure, the virus can critically compromise survival and result in negative consequences. Here, we present the critical management of a COVID-19 patient having pre-existing cirrhosis and review the current issues.
Distal colon metastasis of hepatocellular carcinoma
Authors: Halil Sever İbrahim , Mammadov Tural , İnan Gürcan Nagihan , Yüzer Yıldıray
Published: February 2024

Hematogenous metastasis of hepatocellular carcinoma (HCC), particularly to colon is extremely rare. We presented two cases of colonic metastasis of HCC to the sigmoid colon and rectum. We followed the first patient for six years with chemotherapy, transcatheter arterial radioembolization (four times), and surgical treatment. Liver transplantation was planned because of the patient’s infiltrative HCC in the liver, with no extrahepatic metastasis. Unfortunately, the patient died after the five-year follow-up. The second patient, who was followed for nine years with surgical treatment and chemotherapy, presented with hepatic mass caused by hepatitis B infection. The patient is still in follow-up with multiple peritoneal implants.
A rare coronary artery anomaly: Left main coronary artery arises from right coronary artery
Authors: Koç Okan , Mehmet Uçar Fatih
Published: February 2024

The angiographic incidence of coronary anomalies is 0.3-1%. In angiographic series, the incidence of anomalies of the left main coronary artery originating from the right sinus of Valsalva is very low. Relatively few of these patients develop symptoms such as angina pectoris, arrhythmias, syncope, myocardial infarction, or sudden death. We presented an unusual case of a patient with the left main coronary artery anomalously originating from the right sinus of Valsalva.
Forming the Character of a Physically Healthy Young Generation Through Military Education
Authors: Muchsam Yoki , Sucipto Bambang , Rismawati Rismawati , Rusdianti Imanita Septian , Raharja Agung Rachmat
Published: February 2024

This activity aims to develop the character of the young generation with good physical health through military education at Dodik Belanegara Rindam III Siliwangi, West Bandung. The methods applied include the preparation and implementation of the program, involving the entire academic community. The evaluation results show that the activity went smoothly, and the participants successfully achieved the set goals, showing improvements in physical health and character strengthening through discipline and teamwork. The discussion covers the program's success, involvement of all parties, and benefits felt by the participants. Limitations in logistics and the need for more in-depth evaluation are identified as areas for improvement. Meanwhile, suggestions for further development include the application of comprehensive evaluation methods, increased inter-institutional collaboration, and the development of a more contextual curriculum. Key findings from this study include the program's success in shaping the character and health of the younger generation, highlighting the importance of military education as a means of holistic character formation at the higher education level. These findings provide a basis for the development of similar programs in the future, with a focus on the necessary improvements to enhance their positive impact.
FATORES RELACIONADOS A RECUSA E HESITAÇÃO NA VACINAÇÃO CONTRA O VÍRUS SARS-COV-2 DURANTE A PANDEMIA DA COVID-19 ENTRE PROFISSIONAIS DE SAÚDE
Authors: Santos Emile de Jesus , Silva Alex Maxwelder Borges Sant'Anna , Raulino Júlia Maria de Holanda , Santana Angela Gabriela da Silva , Da Silva Elisabeth do Espirito Santo , Silva Graziela Moreira dos Santos , Cabral Ayara Almeida Souza , Da Cruz Amanda Correia , Ribeiro Daiane Mendes , Lima João Paulo Cunha , De Souza Vitória Batista Gonçalves , Maslinkiewicz Alexandre , Zatti Cassio Adriano
Published: February 2024

A vacinação desempenha um papel crucial na saúde pública, prevenindo o adoecimento por diversas doenças infecciosas e tendo sua eficácia intrinsecamente ligada à adesão da população. Objetivo: Descrever os principais fatores relacionados à recusa e hesitação na vacinação contra o vírus SARS-CoV-2 durante a pandemia da covid-19 entre profissionais de saúde. Metodologia: Trata-se de uma revisão integrativa da literatura realizada nos materiais indexados na Medical Literature Analysis and Retrieval System Online (MEDLINE), Literatura Latino-americana e do Caribe em Ciências da Saúde (LILACS), Base de dados de Enfermagem (BDENF) e Índice Bibliográfico Español en Ciencias de la Salud (IBECS), utilizados os Descritores em Ciências da Saúde (DeCS) em cruzamento com o operador booleano AND e OR, da seguinte forma: COVID-19 AND Vacinação AND Prevenção OR Pessoal de Saúde AND Recusa de Vacinação psicologia OR Recusa de Vacinação, após aplicação dos critérios de elegibilidade foram selecionados 10 trabalhos para compor essa revisão. Resultados: A partir da análise das produções, percebeu-se que os profissionais de saúde hesitaram na vacinação devido a preocupações como riscos desconhecidos, desconfiança na produção rápida, efeitos adversos, medo de contrair a própria doença, falta de estudos, desconfiança nas autoridades de saúde e nas indústrias farmacêuticas, além de receios relacionados ao conteúdo das vacinas e medo de efeitos colaterais, esses fatores variam globalmente e influenciam a aceitação da vacina COVID-19. Considerações finais: A multiplicidade e complexidade das razões que contribuem para a hesitação da vacinação tornam-se evidentes a necessidade de reforçar a divulgação e facilitar o acesso a informações claras sobre a vacina da COVID-19, emergindo como um fator crucial para maior adesão e confiança na vacinação.
INTRODUÇÃO À ERGONOMIA E À ERGOLOGIA: CONTRIBUIÇÕES PARA SE PENSAR AS SITUAÇÕES DE TRABALHO
Authors: Stival Beatriz Pita
Published: February 2024

Este artigo tem como objetivo levantar algumas reflexões sobre as contribuições das abordagens ergonômica e ergológica ao se pensar as situações de trabalho. Para isso, o quadro teórico utilizado abrangeu autores como Alain Wisner, Yves Schwartz, Ivar Oddone e Georges Canguilhem. A conclusão deste artigo nos leva a compreender a importância dos estudos da ergonomia e da ergologia para intervenções no âmbito do trabalho, ao mesmo tempo que nos faz refletir sobre questões essências para pensar as situações de trabalho em sua totalidade.
PRESOS: A PARCELA DA SOCIEDADE NÃO REPRESENTADA
Authors: Cruz Henrique Pinho de Sousa , Gomes Isabeau Lobo Muniz Santos
Published: February 2024

O presente artigo tem por objetivo a análise do impacto do silêncio dos presos na sociedade, frente a suspensão do direito ao voto prevista no artigo 46 da Constituição Federal. Para tanto, são abordadas, no deslinde deste trabalho, as fundamentações jurídico legais sobre a suspensão ao direito de sufrágio dos presos, onde são delineadas as origens jus-filosóficas e históricas da normativa. Subsequentemente, traça-se um paralelo entre as estruturas do cárcere enquanto forma de controle, e em seguida, aponta-se o perfil socioeconômico dos cidadãos silenciados pelo cárcere e o impacto sobre a sociedade em virtude da suspensão ao direito de voto dos presos. Por fim, conclui-se que a suspensão do direito a voto dos presos, representa o mais uma forma de manutenção social das relações estruturais utilizadas pelo poder vigente, bem como representada na forma de controle político.
The Effect of Illumination, Electrode Distance, and Illumination Periods on the Performance of Phototrophic Sediment Microbial Fuel Cells (PSMFCs)
Authors: Harimawan Ardiyan , Devianto Hary , Khodiyat Nicholas , Gatalie Kreszen Livianus , Aslan Christian
Published: February 2024

Microbial fuel cells (MFCs) can potentially be used to overcome issues with battery powered light buoys and their frequent maintenance. In this study, a phototrophic sediment microbial fuel cell (PSMFC) was chosen, as the microalgae provide oxygen to be reduced on the cathode and to release the necessary nutrients for the bacteria on the anode. To achieve this, we studied the effect of illumination, the period of the illumination, and the distance between 9-cm2 stainless steel mesh electrodes on the performance of the MFC. The illuminated cells were able to produce higher OCP (max. 205.2 mV) and higher power density (max. 0.68 mW/m2). However, the highest current was achieved during the unilluminated variation (max. 5.3 μA unilluminated and 3.3 μA illuminated). Prolonged illumination produced a higher OCP, current, and power density. A longer electrode distance produced a higher OCP, power density, and current. SEM analysis showed that biofilm formation tended to be scattered at lower electrode distance and more clumped (filling the anode area) at higher electrode distance. Through FTIR analysis, it was found that all MFC variations had the same organic matter, but a more concentrated organic content was found in the MFC at longer electrode distances.
Discussion of “Assessment of the coefficient of consolidation with Queensland data”
Authors: Litwinowicz Alexander
Published: February 2024

This paper presents a discussion of “Assessment of the coefficient of consolidation with Queensland data” by Burt G. Look. https://doi.org/10.56295/AGJ5825.
The Implementation of Cool Japan Strategy during Covid-19 Pandemic
Authors: Salsabila Nahda , Akbar Ibda Khaliq Bijitama
Published: February 2024

Abstract: The 2020 global pandemic did a significant blow to creative industries worldwide, including animation production industries. Japan as one of the most prominent players in animation industries, with its popular animation style called anime, also suffered from the pandemic. This study aims to analyze the influence of the Cool Japan Strategy to Japan anime industry before and after the Covid 19 pandemic. This research uses the qualitative method of review and read with literature study. The results show that the Cool Japan Strategy has a significant influence on the development of the anime industry, especially in terms of marketing and promotion. However, the COVID-19 pandemic also had a significant impact on the anime industry, with a decrease in revenue and changes in consumer behavior. Nonetheless, Cool Japan Strategy helps the anime industry to adapt to these changes, especially through the use of digital technology. In conclusion, Cool Japan Strategy has an important role in promoting the anime industry, and the ability to adapt to difficult environmental changes such as the pandemic can help the anime industry to continue to thrive in the future.
Keywords: Cool Japan Strategy, anime industry, COVID-19, pandemic, popular culture
ỨNG DỤNG KHÁNG THỂ ĐƠN DÒNG mAbNS1-DENV1-4 PHÁT HIỆN KHÁNG NGUYÊN NS1 CỦA CÁC TÝP VIRUS DENGUE BẰNG PHƯƠNG PHÁP ELISA
Authors: Đỗ Như Bình , Hoàng Xuân Cường , Trần Thị Hồng Thịnh , Võ Thị Bích Thủy , Trịnh Thế Sơn , Phạm Hùng Tiến
Published: February 2024

Mục tiêu: Sử dụng kỹ thuật ELISA với thành phần là kháng thể đơn dòng được tạo ra từ kháng nguyên tái tổ hợp NS1 gộp bốn týp DENV1-4 để phát hiện căn nguyên gây bệnh sốt xuất huyết. Phương pháp nghiên cứu: Nghiên cứu thực nghiệm labo, kháng thể đơn dòng mAbNS1-DENV đặc hiệu kháng NS1 của 4 týp virus Dengue được sử dụng để phát triển và tối ưu hóa xét nghiệm ELISA gián tiếp, cho phép phát hiện chính xác DENV1-4 trong huyết thanh bệnh nhân (BN). So sánh độ nhạy, độ đặc hiệu với phương pháp real-time PCR. Kết quả: Kỹ thuật ELISA sử dụng kháng thể đơn dòng mAbNS1-DENV1-4 có độ nhạy 100%, độ đặc hiệu 97,75%, giá trị dự đoán dương 98,37% và giá trị dự đoán âm 100%. Hơn nữa, xét nghiệm này đặc biệt phát hiện cả kháng nguyên NS1 DENV-4 trong nhóm mẫu nghi ngờ (9/63). Kết luận: Kháng thể đơn dòng mAbNS1-DENV1-4 có giá trị ứng dụng chẩn đoán nhanh các týp DENV với độ nhạy và độ đặc hiệu cao.
NGHIÊN CỨU GIÁ TRỊ NLR, PLR VÀ MỘT SỐ CHỈ SỐ HÓA SINH MÁU Ở BỆNH NHÂN U LYMPHO ÁC TÍNH KHÔNG HODGKIN TẠI BỆNH VIỆN QUÂN Y 103
Authors: Nguyễn Thị Thu , Nguyễn Trọng Hà , Nguyễn Văn Bằng , Tăng Xuân Hòa , Nguyễn Xuân Khái
Published: February 2024

Mục tiêu: Xác định ngưỡng giá trị tối ưu của tỷ lệ số lượng tuyệt đối bạch cầu trung tính/bạch cầu lympho (Neutrophile to Lymphocyte Ratio - NLR), tỷ lệ giữa số lượng tiểu cầu/bạch cầu lympho (Platelet to Lymphocyte Ratio - PLR) trong tiên lượng, đáp ứng điều trị bệnh u lympho lành tính không hodgkin (ULATKH) và mối liên quan với một số yếu tố lâm sàng. Phương pháp nghiên cứu: Nghiên cứu hồi cứu, tiến cứu và mô tả cắt ngang trên 31 bệnh nhân (BN) ULATKH điều trị tại Bộ môn - Trung tâm Nội dã chiến, Bệnh viện Quân y 103, từ tháng 01 - 12/2022 và 31 người khỏe mạnh được khám, xét nghiệm tại phòng khám bệnh tương đồng về tuổi giới; xác định giá trị NLR, PLR và một số chỉ số sinh hóa máu. Kết quả: Tuổi trung bình là 60, nam (67,74%), sút cân (29,03%), ra mồ hôi trộm (16,13%) là hai triệu chứng toàn thân thường gặp nhất; chỉ số toàn trạng PS (Performance Status) 0-2, chủ yếu PS 0-1 (90,32%). BN có hạch to (80,65%), có một nhóm hạch (45,16%). Hoá mô miễn dịch: CD20 (+) (91,30%). Ngưỡng giá trị tối ưu của chỉ số NLR, PLR trong tiên lượng bệnh là: 1,85 và 127,3; có mối liên quan với chỉ số toàn trạng và số nhóm hạch. Kết luận: BN ULATKH tuổi trung bình: 60, nam (67%), điểm toàn trạng chủ yếu PS 0-1; BN đa số có 1 nhóm hạch, triệu chứng toàn thân hay gặp (sút cân và ra mồ hôi trộm). Ngưỡng giá trị tối ưu của chỉ số NLR, PLR trong tiên lượng bệnh là: 1,85 và 127,3. NLR và PLR có mối liên quan có ý nghĩa thống kê với một số triệu chứng toàn thân, chỉ số toàn trạng và số nhóm hạch.
ĐÁNH GIÁ KẾT QUẢ GHÉP THẬN TẠI BỆNH VIỆN TRUNG ƯƠNG QUÂN ĐỘI 103 LÀO
Authors: Vibounmy Keovithoun , Savengxay Dalasat , Khonevilay Khinthavong , Pan Philavong , Phimmasone Phommavongsa , Vongmyxay Inthavong , Sonephay Lorsingkham , Vũ Nhất Định , Nguyễn Văn Nam , Buasing Inthavong
Published: February 2024

Mục tiêu: Đánh giá kết quả 6 ca ghép thận đầu tiên được thực hiện tại Bệnh viện Trung ương Quân đội (BVTWQĐ) 103 Lào. Phương pháp nghiên cứu: Nghiên cứu tiến cứu, mô tả, theo dõi dọc trên 6 bệnh nhân (BN) bệnh thận mạn (BTM) giai đoạn cuối được ghép thận từ người cho sống, từ tháng 12/2022 - 12/2023. Kết quả: Tại thời điểm 6 tháng sau ghép, không ghi nhận biến chứng nào sau ghép; chức năng thận ổn định dần trong 6 tháng đầu sau ghép thể hiện qua các chỉ số ure, creatinine máu và mức lọc cầu thận ước tính; nồng độ thuốc C0 của Tacrolimus dần ổn định về ngưỡng khuyến cáo; sau ghép cải thiện tình trạng tăng huyết áp, thiếu máu; các chỉ số huyết học ổn định dần về mức bình thường, không ghi nhận biến đổi chỉ số tiểu cầu. Kết luận: Sau ghép 6 tháng, 6 BN đều không ghi nhận biến chứng nào cần xử trí, chức năng thận ổn định.
ĐÁNH GIÁ ẢNH HƯỞNG CỦA ĐA HÌNH RS1048943 TRÊN GEN CYP1A1 VÀ ĐỨT GÃY DNA TINH TRÙNG
Authors: Trần Văn Khoa , Triệu Tiến Sang , Nguyễn Văn Phong , Nguyễn Đức Sơn , Tạ Thị Bình , Vũ Ngọc Huyền
Published: February 2024

Mục tiêu: Tối ưu kỹ thuật Tetra-ARMS PCR xác định SNP rs1048943; Khảo sát tần số alen, kiểu gen tại điểm đa hình đơn rs1048943; Phân tích mối liên quan giữa điểm đa hình đơn rs1048943 trên gen CYP1A1 và đứt gãy DNA tinh trùng trên đối tượng người Việt Nam. Phương pháp nghiên cứu: Mẫu tinh trùng của 103 nam giới có tỷ lệ đứt gãy DNA tinh trùng trung bình và cao (DFI > 15%) và 125 nam giới có tỷ lệ đứt gãy DNA tinh trùng thấp (DFI ≤ 15%) được tách chiết DNA. Tiến hành xác định đa hình rs1048943 trên các mẫu bằng kỹ thuật Tetra-ARMS PCR, sau đó phân tích và thống kê dữ liệu. Kết quả: Kỹ thuật Tetra-ARMS PCR được tối ưu và ứng dụng thành công để xác định kiểu gen của điểm đa hình rs1048943. Phân bố kiểu gen của đa hình rs1048943 trên các nhóm tuân theo Định luật Hardy-Weinberg (HWE) (p > 0,05), tuy nhiên không có mối liên quan giữa đa hình rs1048943 gen CYP1A1 với nguy cơ đứt gãy DNA tinh trùng ở người Việt Nam. Kết luận: Kỹ thuật Tetra-ARMS PCR được tối ưu và ứng dụng thành công để xác định kiểu gen của điểm đa hình rs1048943. Không có mối liên quan giữa đa hình rs1048943 gen CYP1A1 với nguy cơ đứt gãy DNA tinh trùng ở người Việt Nam.
KẾT QUẢ THU DUNG VÀ ĐIỀU TRỊ CỦA BỆNH VIỆN DÃ CHIẾN CẤP 2 SỐ 4 VIỆT NAM TẠI PHÁI BỘ GÌN GIỮ HÒA BÌNH LIÊN HỢP QUỐC NAM SUDAN
Authors: Lê Việt Anh , Hồ Hữu Phước , Phạm Mạnh Cường , Nguyễn Văn Ninh , Nguyễn Thế Anh , Trần Viết Tiến
Published: February 2024

Mục tiêu: Đánh giá kết quả thu dung và điều trị của Bệnh viện Dã chiến cấp 2 số 4 (BVDC 2.4) Việt Nam tại Nam Sudan trong nhiệm kỳ từ tháng 5/2022 - 7/2023. Phương pháp nghiên cứu: Nghiên cứu hồi cứu, mô tả cắt ngang, không đối chiếu trên 1474 người bệnh (NB) là nhân viên Liên Hợp Quốc (LHQ), khám và điều trị tại BVDC 2.4 Việt Nam - Nam Sudan, từ tháng 5/2022 - 7/2023. Kết quả: Trong nhiệm kỳ 14 tháng, BVDC 2.4 Việt Nam đã tiếp nhận 1474 NB, đa số < 40 tuổi (96,74%), tỷ lệ nữ giới là 10,24%, lực lượng vũ trang (quân đội và cảnh sát) là chủ yếu (66,96%), 100% ngôn ngữ giao tiếp là Tiếng Anh. Cơ cấu bệnh lý đa dạng, tập trung vào nhóm bệnh nội khoa (31,28%), cơ-xương-khớp (22,25%), chấn thương-vết thương (15,12), các bệnh lý truyền nhiễm (12,42%) và răng miệng (11,13%). Phẫu thuật 18 ca (viêm ruột thừa cấp là chủ yếu, chiếm 27,78%) và cấp cứu vận chuyển đường không 10 ca; đảm bảo an toàn 100%. Ngày điều trị trung bình nhóm phẫu thuật là 4,52 ± 1,08 và nhóm NB điều trị nội khoa nội trú là 5,39 ± 1,86 ngày. Kết luận: BVDC 2.4 Việt Nam hoàn thành tốt nhiệm vụ thu dung và điều trị tại Nam Sudan trong nhiệm kỳ từ tháng 5/2022 - 7/2023 với 1474 NB, đảm bảo đúng quy trình LHQ, an toàn tuyệt đối, không tai biến và biến chứng trong quá trình điều trị, tất cả các ca cấp cứu vận chuyển đường không đều kịp thời, an toàn và đúng chỉ định.
KIỂM SOÁT TẾ BÀO UNG THƯ ĐẠI TRÀNG TĂNG SINH THÔNG QUA ỨC CHẾ PROTEIN THAM GIA SỬA CHỮA TỔN THƯƠNG DNA
Authors: Đỗ Quỳnh Chi , Bùi Khắc Cường
Published: February 2024

Mục tiêu: Sửa chữa tổn thương DNA đóng vai trò quan trọng trong sự tồn tại và phát triển của tế bào. Ức chế sửa chữa tổn thương DNA là mục tiêu của một số liệu pháp điều trị ung thư. Nghiên cứu này được tiến hành để đánh giá tác dụng ức chế tế bào ung thư đại tràng của CB5083, chất ức chế đặc hiệu của p97 - một protein tham gia vào quá trình sữa chữa DNA. Phương pháp nghiên cứu: Nghiên cứu sử dụng CB5083, chất ức chế đặc hiệu p97 và dòng tế bào ung thư đại tràng HCT116. Các thử nghiệm được sử dụng bao gồm thử nghiệm tăng sinh tế bào, di trú tế bào, thử nghiệm chu kì tế bào bằng phương pháp đếm tế bào dòng chảy. Kết quả: CB5083 ức chế tăng sinh tế bào HCT116 in vitro. CB5083 cũng ảnh hưởng đến quá trình di trú tế bào và phân bố tế bào ở các pha khác nhau trong chu kỳ tế bào. Kết luận: Ức chế đặc hiệu protein tham gia sửa chữa tổn thương DNA p97 bằng CB5083 có tác dụng kìm hãm tăng sinh tế bào ung thư đại tràng in vitro.
BREVES DE MEDECINE
Authors: RUELLE Y , CADWALLADER JS , VAILLANT H
Published: February 2024

Dépression périnatale et risque de mortalité globale L’association entre la présence d’une dépression périnatale et la mortalité globale a été explorée à partir du Registre national de santé suédois. Entre 2001 et 2018, 86 588 femmes ont eu un diagnostic de dépression périnatale, avec prise en charge spécialisée et traitement antidépresseur. 865 510 femmes sans dépression périnatale ont été appariées selon l’âge et l’année de grossesse. Pour ajuster sur le contexte familial, 270 586 soeurs avec dépression périnatale ont été comparées aux soeurs n’ayant pas de dépression périnatale et ayant eu un enfant dans une période proche. Après dix-huit ans de suivi, 522 décès de femmes ayant une dépression périnatale à 31 ans d’âge médian ont été répertoriés. Leur risque de décès toutes causes confondues était multiplié par 2,1 (IC95 = 1,86-2,40). Le risque était plus important quand la dépression survenait en post-partum versus antepartum (HR = 2,71 ; IC95 = 2,26-3,26 vs 1,62 ; IC95 = 1,34-1,94). Le sur-risque persistait en cas d’antécédent dépressif, de même qu’en comparant les soeurs d’une même famille. Il concernait les causes naturelles et non naturelles. Le risque de mortalité globale était le plus élevé dans la première année suivant la grossesse. Enfin, le suicide était plus fréquent chez les femmes ayant une dépression périnatale (HR = 6,34 ; IC95 = 4,62-8,71). Les auteurs concluaient donc au fait que la dépression périnatale s’inscrivait dans une trajectoire de vie en lien avec des facteurs de vulnérabilité, causes ou conséquences de la dépression et du mal- être pendant et juste après la grossesse. BMJ 2024. doi: 10.1136/bmj-2023-075462.
Analisis Kinerja Karyawan Melalui Kepuasan Kerja, Kompensasi, dan Displin Kerja Pada Karyawan L’Avenue Office & Residences
Authors: Annisa Zahra Putrie  , Yosafat Puji Hastoko
Published: February 2024

This study intends to determine whether the analysis of employee performance at L'Avenue Office & Residences has an impact on job satisfaction, compensation, and work discipline. In this research using accidental sampling research technique with non-probability sampling. L'avenue office & residences employees as many as 100 people who can be used as a sample of those who happen to meet with researchers are considered as a reliable source of data. This research method is quantitative research using multiple linear regression analysis techniques. The results of this study show that job satisfaction has no effect on employee performance, compensation has no effect on employee performance, work discipline has a significant effect on employee performance at L'avenue offices & residences. But simultaneously these three variables have a significant effect on employee performance at L'avenue office & residences
Sex, gender, race and ethnicity matter in limb preservation in North America
Authors: Blanchette Virginie , Kayssi Ahmed
Published: February 2024

The causes of sex, gender, racial and ethnic disparities in health care are multifactorial and reflect differences in biological vulnerability to disease as well as differences in social resources, environmental conditions and health-care interventions. These factors are well known to influence the fate of people with diabetes-related foot complications such as diabetic foot ulcer, infection and amputation. In this paper, the authors discuss the important concepts of health equity, equality and disparity in relation to the impact of sex, gender, race and ethnicity on limb preservation.
دور ابعاد الملكية النفسية في الحد من تأثيرات القيادة السامة: بحث تحليلي لعينة من شركات وزارة الصناعة والمعادن
Authors: حسن Ali , ابراهيم Ibtisama
Published: February 2024

يهدف البحث الحالي إلى توضيح الدور الذي تلعبه الملكية النفسية بابعادها في الحد من تاثيرات القيادة السامة بابعادها في وزارة الصناعة والمعادن.وانطلق البحث من مشكلة اساسية تمثلت في التساؤل الاتي ( استخدام الملكية النفسية وتطبيقها في الحد من التاثرات السلبية للقيادة السامة). اذ استخدم الباحث المنهج الوصفي التحليلي واستخدم الأدوات الإحصائية المختلفة في البرنامج الاحصائي  (SPSS V.23)لتحليل العلاقة بين متغيرات البحث الرئيسية والإجابة على التساؤل الرئيس والتحقق من الفرضيات ومن هذه الوسائل (معاملات الانحدار، ومعاملات الارتباط، والمتوسطات، والانحرافات المعيارية، والتباينات. بالإضافة إلى ذلك تم استخدام الرسوم البيانية والمخططات المختلفة لتوضيح العلاقة بين متغيرات البحث وأبعادها الفرعية. تم اختيار العينة عشوائية من  العاملين في بعض الشركات المختارة التابعة لوزارة الصناعة والمعادن في بغداد اذ بلغ حجم العينة 124 فرداً. ومن أهم النتائج وجود تأثير لمتغير الملكية النفسية بابعادة الاربعة في الحد من سلوكات القيادة السامة بابعدها الخمسة. اذ  أن الملكية النفسية النابعة من شعور الأفراد بالتملك والارتباط، تؤثر على المواقف والسلوكيات في سياقات مختلفة، بما في ذلك القيادة السامة اذا يمكن ان تكون عواقب تلك السلوكيات ضارة للأفراد والمنظمات لو تركت دون معالجة.
PENERAPAN MODEL PEMBELAJARAN PROBLEM BASED LEARNING UNTUK MENINGKATAN HASIL BELAJAR EKONOMI PESERTA DIDIK KELAS XI SMA NEGERI 1 TOMA
Authors: Dao Melinawati
Published: February 2024

This research aims to improve the learning outcomes of Economics among students of the eleventh-grade Social Sciences program at SMA Negeri 1 Toma through the implementation of the PBL cooperative learning model. The research method employed is action research involving 21 eleventh-grade Social Sciences students as the research subjects. The research is conducted in two cycles by collecting data through learning outcome tests, which are then analyzed using qualitative descriptive techniques. The results indicate that the implementation of the cooperative learning model effectively enhances students' learning outcomes significantly. The average learning outcomes of students increased from 76.77 in the first cycle to 82.97 in the second cycle, indicating an improvement of 6.22 points. This improvement reflects a significant enhancement in students' learning achievement from the category of fairly high in the first cycle to high in the second cycle. Consequently, it can be concluded that the application of the cooperative learning model has a positive impact on enhancing students' learning outcomes in Economics at SMA Negeri 1 Toma.
PENGARUH PERPUTARAN MODAL KERJA, PERPUTARAN KAS, PERPUTARAN PIUTANG, DAN PERPUTARAN PERSEDIAAN TERHADAP PROFITABILITAS PERUSAHAAAN SUB SEKTOR FOOD AND BAVERAGE YANG TERDAFTAR DI BURSA EFEK INDONESIA
Authors: Khairun Umrah  , Nurman  , Andi Mustika Amin
Published: February 2024

This study aims to determine the effect of working capital turnover, cash turnover, accounts receivable turnover, and inventory turnover on profitability in food and beverage sub-sector companies listed on the Indonesia Stock Exchange. The variables in this study are working capital turnover, cash turnover, accounts receivable turnover, inventory turnover (independent variable), and profitability as measured using the NPM ratio (dependent variable). The population in this study are food and beverage sub-sector companies listed on the Indonesia Stock Exchange. While the sample in this study there were 19 companies that met the sample selection criteria. Data collection using documentation techniques. the analysis technique used is the statistical method of multiple linear regression. The results showed that partially working capital turnover, cash turnover, accounts receivable turnover, and inventory turnover have a negative effect on profitability (NPM). Meanwhile, working capital turnover, cash turnover, accounts receivable turnover, and inventory turnover simultaneously have a positive effect on profitability (NPM) in food and beverage companies listed on the IDX.
TELAAH TEKNOLOGI INFORMASI DAN SISTEM INFORMASI DALAM ORGANISASI DENGAN LINGKUNGAN
Authors: Agustika Fitriah , Siregar Sadrak , Obara Dony , Paramarta Vip
Published: February 2024

The purpose of this research is to describe the use of information technology and information systems in organizations with the environment. This research is a literature review, with a descriptive approach. The results of the theoretical analysis and studies of relevant previous studies are that information technology can be placed/treated as a mediating (intervening) variable in the relationship between environmental attributes and organizational structure attributes. This is due to the high level of utilization/use of information technology in companies and the application of information technology is an important requirement in managing the company's business activities. The role of technology in the relationship between environmental attributes and organizational structure attributes is information technology as a mediator in this relationship. Information technology has become an important element in achieving organizational goals to overcome environmental uncertainties. The existence of information technology is needed to create the structural response desired by management in anticipating environmental changes
PENGARUH WORK ENVIRONMENT, STRES KERJA, DAN DUKUNGAN KELUARGA YANG DIMEDIASI OLEH DUKUNGAN KELUARGA TERHADAP KINERJA UMKM
Authors: Qudrotul Ainiyah Lissa , Qristin Violinda  , Noni Setyorini
Published: February 2024

The Influence of Work Environment, Job Stress and Business Management Mediated by Family Support on the Performance of MSMEs in Pedurungan District" (Case Study of MSMEs in Pedurungan District). PGRI University Semarang Management Study Program 2023. This research uses a probability sampling technique with the Cluster Random Sampling method as a sample determination technique. The data analysis process uses the Structural Equation Model Partial Least Square (SEMPLS) analysis model with the help of the SmartPLS 3.0 analysis tool. The population used in this research were MSME owners located in Pedurungan District and the sample used was 350 respondents. Primary data by distributing questionnaires via Google Form. The results of the analysis and discussion show that there is a positive and significant influence between the Work Environment variable (X1) which is mediated by Family Support (Z) on the MSME Performance variable (Y) in partial terms, with a t-statistic of 2.127 and a p-value of 0.034 < 0.05. There is a positive and significant influence between the Work Stress variable (X2) which is mediated by Family Support (Z) on the MSME Performance variable (Y) in part, with a t-statistic of 2.185 and a p-value of 0.029 < 0.05. There is a significant influence between the Business Management variable mediated by Family Support (Z) on the MSME Performance variable (Y) in partial terms, with a t-statistic of 2.067 and a p-value of 0.009 < 0.05