bluuebunny/crossref_metadata_2025 huggingface dataset:
How a learning factory approach can help to increase the un- derstanding of the application of machine learning on produc- tion planning and control tasks.
Authors:   Institute of Product and Process Innovation Leuphana University Lüneburg, Rokoss Alexander , Kramer Kathrin , Schmidt Matthias
Published: September 2021

Technological progress and increasing digitalization offer many opportunities to production companies, but also continually present them with new challenges. The automation of processes is progressing in manufacturing areas and technical support systems, such as human-robot collaboration, are leading to significant changes in workflows. However, in other areas of companies large parts of the work are still done by humans. This is partly the case with the use of production data. Although much data is already collected and sorted automatically, the final evaluation of this data and especially decision-making is often done by humans. In particular, this is the case for decisions that cannot clearly be made based on conditional programming. The use of machine learning (ML) represents a promising approach to make such complex decisions automatically. A sharp increase in scientific publications in the recent years demonstrates the trend that more and more companies and institutions are looking into the use of machine learning in production. Since ML is beeing applied across several industries, the resulting massive shortage of skilled workers in the field of ML has to be addressed in short and medium terms by training and educating existing employees in production companies. A contemporary approach to building competencies in dealing with problems in the manufacturing sector is the use of learning factories as a knowledge transfer enabler. They offer learners the opportunity to try out methods in a realistic environment without having to fear negative consequences for the company. The results of actions performed by participants can be experienced directly without any time delay, resulting in better learning results compared to conventional face-to-face teaching. This chapter shows how learning factories can support teaching machine learning methods in the field of PPC. For this purpose, the determination of lead times using real data sets is addressed with ML-based methods. Parallelly, the competencies required for the respective tasks were extracted. Based on this, elements of a learning factory were designed that simplifies the considered processes, so that the problem can be easily understood by learners. The last part of the chapter describes several learning factory game phases aiming on teaching the identified competencies. The described learning factory enables participants to setup ML-based projects in the context of manufacturing.
Spectator’s Emotional Response to Art Nouveau Images in A. V. Khvastunova’s Graphics
Authors: Popov Alexei Valentinovich
Published: September 2021

The paper aims to identify specificity of a spectator’s emotional response to Art Nouveau images created by the talented modern painter A. V. Khvastunova. The article reveals the potential of the figurative language introduced by the Miriskusniks (members of the artistic movement “Mir Iskusstva (World of Art)” (1898-1927)). The author shows how the Art Nouveau style influences a spectator’s emotional response, and herein lies scientific originality of the study. The conducted analysis allows concluding that at the beginning of the XXI century, A. V. Khvastunova successfully uses such elements of the Art Nouveau style as line, stain and stroke, which not only decorate a picture but express the author’s emotions, thus participating in an image formation.
Axiological Dimension of the Modern Chinese Culture
Authors: Duminskaya Anastasiya Valiyevna
Published: September 2021

The purpose of the research is to determine the features characterising cultural modernisation influence on the development of the axiological aspect of the Chinese culture. The article considers three main groups of factors driving the development of the Chinese cultural values in the setting of modernisation. Scientific novelty of the research lies in analysing the value structure of the modern Chinese culture, using the proposed model as a tool for its study. As a result, it is proved that the axiological dimension of the Chinese culture can be considered according to regionalisation, globalisation and modernisation facets, influence of which can be identified by analysing the Chinese culture bearers’ value attitudes, directions of various modernisation practices in the field of culture, as well as information channels that promote exchange and dissemination of global values in the process of cultural globalisation.
Conclusion
Authors: Demchenko Aleksandr Ivanovich
Published: September 2021

Editor-in-Chief’s Column accomplishes publication of a large series of artistic-historical essays which consecutively consider the major epochs. These reviews aim to outline the humanity’s evolution panorama through the lens of all the art forms resulting in ontological generalisation. Ancient World, Antiquity, Middle Ages, Renaissance, Baroque, Enlightenment, Romanticism, Post-Romanticism, Modernity I (Early ХХ Century), Modernity II (Middle of ХХ Century), Modernity III (Late ХХ Century), Postmodernity, “golden age” of the Russian artistic culture were examined.
Philosophical Consultancy: Responding to the VUCA World Challenges
Authors: Ivanova Olga Ernstovna
Published: September 2021

The purpose of the research is to shed light on instrumentality of philosophical consultancy in responding to the VUCA world challenges. Scientific novelty of the research lies in studying intellectual and value-based instrumentality of philosophical response in the form of consultancy to the VUCA world challenges. As a result, it is proved that instrumentality of philosophical consultancy is provided by application of philosophical ideas and methods to solve a specific problem that is significant for a subject, as well as by dialectically and logically related mental procedures of “diving into depth” to understand essence of a problem and “breaking the mould” when solving a problem.
Dzungar Khanate as Potential Hegemon in the Mongolian World: Causes of Failure
Authors: Kushkhov Boris Khabizhevich
Published: September 2021

The paper tries to explain why Dzungar Khanate did not manage to establish itself as a leader of the Mongolian world. Scientific originality of the study lies in the fact that relying on the systemic approach, the author analyzes military-political, socio-economic, cultural and religious aspects of regional leadership. The conducted analysis allows concluding that Dzungar Khanate was not capable to establish its hegemony in Northeastern Asia due to inefficient foreign policy and due to state structure imperfections caused by lack of political, economic, cultural and religious resources.
Spatial Nominations in Athanasius the Great’s Hagiography
Authors: Ilyin Boris Borisovich
Published: September 2021

The paper aims to reveal specificity of the space category realization in Athanasius the Great’s hagiography. The article analyses nominal lexical units (spatial nominations) representing space image in the hagiographic text. It is shown that urban space plays the key role in textual space organization. It is noted that the sainthood conception determines axiological interpretation of space in the hagiographic text. Scientific originality of the study lies in the fact that the space category in the hagiographic text is examined through the lens of spatial nomination semantics. The findings indicate that in Athanasius the Great’s hagiography, nominal lexemes with spatial meaning represent geographic space, serve as locus identifiers and acquire religious and ethical connotations typical of the hagiographic genre.
Typological Peculiarities of Teaching the German Phonetics in the Tatar-Speaking Audience
Authors: Sibgatullina Alfiya Ashrafullovna
Published: September 2021

Relying on a typological analysis of the German and Tatar phonological systems, the author proposes methodological recommendations on teaching the German pronunciation in the Tatar-speaking audience. The article reveals the potential of the comparative-contrastive method in teaching a foreign language, provides a comparative-typological analysis of the German and Tatar languages, compares the German and Tatar vowel systems. Scientific originality of the study involves developing a system of exercises aimed to form the Tatar-speaking learners’ German-language phonetic competence. The research findings are as follows: the author introduces a classification of phonetic exercises (exercises to develop auditory skills, exercises to develop pronunciation skills, exercises to develop rhythmic-prosodic skills), identifies linguistic and psychological components of phonetic training.
Concept WORLD in the Russian and Chinese Linguistic Worldviews
Authors: Fomenko Irina Borisovna
Published: September 2021

The study aims to identify semantic, linguocultural, associative components that are a part of the semantic structure of the concept WORLD in the Russian and Chinese linguistic worldviews. The study is novel in that it is the first to consider components of the concept WORLD in the Russian and Chinese linguistic worldviews at the semantic, cultural-semantic and associative-semantic levels in the comparative aspect. The article presents results of analysing set expressions, proverbs, sayings of the two languages compared, as well as reactions of the Russian and Chinese respondents to the stimulus word “world” obtained during free associative experiments, on the basis of which specificity of the concept associative-semantic perception by the Russian and Chinese native speakers was described.
Scottish Émigré Poetry of the XIX Century: Realia, Symbols, Motives
Authors: Velilaeva Lilia Raimovna
Published: September 2021

The article analyzes the Scottish émigré poetry of the XIX century. The paper traces transformation of the Scottish realia into symbols in the context of relevant motives of removal. The researcher identifies artistic peculiarities of poems in which realia acquire symbolic meaning, proposes a classification of motives of return to the Motherland, which constitutes scientific originality of the study. As a result, it is shown that the Scottish émigré poets described Motherland-Scotland as a “fairy world” transforming realia into symbols, which is typical for émigré discourse. The motive of “fairy world” is associated with motives of vision/dream/reverie and sea voyage.
Modern Interpretation of Traditional Fabulous Motives (by the Example of ATU 325 “The Magician and His Pupil” Fairy Tale Plot)
Authors: Troshkova Anna Olegovna
Published: September 2021

The paper traces transformation of the traditional fairytale plot ATU 325 “The Magician and His Pupil” in the modern Russian fanfiction. The research material includes over 1500 fanfics based on the Russian and foreign fiction. The study uses the comparative-contrastive method. Scientific originality of the research lies in the fact that the author traces the vector of transformation of the traditional fairytale plot ATU 325 “The Magician and His Pupil”: “myth - folklore - literature - fanfiction”. The research findings are as follows: the author identifies recurrent ATU 325 motives frequently used in fanfiction, reveals specificity of their integration into textual space of modern fanfiction and concludes about ambiguous attitude of fanfiction authors towards the motive under analysis.
E. Zamyatin’s Aesthetic Principles
Authors: Kurochkina Anzhelika Valerievna
Published: September 2021

The purpose of the study is to identify distinct nature of E. Zamyatin’s aesthetic principles. The article reflects influence of various artistic trends (romanticism, realism, symbolism) on formation of the writer’s worldview and creative principles. Scientific novelty of the study lies in formulating Zamyatin’s main aesthetic principles, which make it possible to identify distinct nature of his literary method (“neorealism”), peculiarities in his worldview. As a result, duality of the writer’s standpoint is proved: denying literary value of realist and socialist realist literature, he relies on the aesthetic principles of classical romanticism and realism, recognises symbolism contributions in the search for new forms and content.
Analisis Faktor yang Berpengaruh pada Kecenderungan Kecurangan Akuntansi (Fraud): Studi pada LPD Kecamatan Tabanan
Authors: Pradnyanitasari Putu Dian , Priliandani Ni Made Intan , Sanjaya I Ketut Puja Wirya
Published: September 2021

The purpose of this paper is to examine the influence of the suitability of compensation, internal control of cash and individual morality to the tendency of the accounting fraud (fraud). There were 36 respondents who were workers in LPD Tabanan Regency using purposive sampling and multiple linear regression analysis was used to answer the research hypothesis. The study found that all the factors tested had a negative effect on the tendency of accounting fraud (fraud).
The ROS: Kinetic Kame for Humanoid Robot BarelangFC
Authors: Susanto Susanto , Suroto Junito , Analia Riska
Published: September 2021

A collaborative robot such as humanoid robot which able to play soccer consist tons of software framework such as servo controller, vision system, strategy receiver and transmitter, sensors, and coordination system. All these frameworks needed to be integrated to simplify the command of creating the complexity of the robot behaviors. To overcome these problems, the Robot Operating System (ROS) can be implemented on each robot. This paper presented the implementation of the ROS: Kinetic Kame in order to integrated the whole framework which is existed in the robot. To verify the performance of this system, some experiments has been done in real-time application. From the experimental results, the ROS: Kinetic Kame able to integrate each software framework of the robot in very good response.
Pengaruh Holding Time Annealing terhadap Perubahan Mikrostruktur Baja Struktur S690QL dan S235JR
Authors: Wibowo Ari , Widiastuti Hanifah , Arifin Nurul Laili , Aryanto Nugroho Pratomo
Published: September 2021

Baja struktur S690 dan S235JR banyak digunakan pada peralatan berat untuk struktur kerangka utama. Pada umumnya, proses fabrikasi peralatan berat selalu melibatkan proses pengelasan yang berpotensi mengubah sifat mekanis material. Oleh karena itu, pada proses fabrikasi yang melibatkan kedua baja tersebut, dilakukan proses perlakuan panas setelah pengelasan untuk memodifikasi sifat mekanisnya. Proses perlakukan panas ini dilakukan terutama untuk menghilangkan tegangan sisa dan menurunkan kegetasan melalui proses annealing. Dalam penelitian ini, annealing dilakukan pada kedua baja tersebut untuk melihat pengaruh proses perlakuan panas pada kekerasan dan struktur mikro material. Pada kedua baja tersebut dilakukan proses annealing dengan suhu 760 oC, holding time 2, 4, 6, 8, dan 10 jam serta laju pendinginan 20 oC/jam. Setelah proses annealing, pengamatan dengan mikroskop metalurgi dilakukan untuk melihat struktur mikro akhir dilanjutkan dengan pengujian kekerasan material menggunakan metode Rockwell B. Hasil pengujian menunjukkan bahwa holding time annealing mempengaruhi fasa dan ukuran butir serta kekerasan baja S690 dan S235JR. Ukuran butir terbesar terbentuk dengan holding time 10 jam sementara kekerasan terendah juga didapatkan pada holding time 10 jam.  Holding time annealing juga mempengaruhi perubahan fasa dari fine bainite menjadi ferrite dengan butir yang besar pada S690 dan menurunkan ukuran pearlite pada S235JR. Hasil pengujian juga menunjukkan bahwa holding time yang lama berpotensi menimbulkan efek dekarburisasi pada baja.
The Island of Extremes: Giants and Dwarfs on a Small Remote Island
Authors: Itescu Yuval , Foufopoulos Johannes , Schwarz Rachel , Lymberakis Petros , Slavenko Alex , Gavriilidi Ioanna-Aikaterini , Meiri Shai , Pafilis Panayiotis
Published: September 2021

Body size evolution on islands is widely studied and hotly debated. Gigantism and dwarfism are thought to evolve under strong natural selection, especially on small remote islands. We report a curious co-occurrence of both dwarf and giant lizards on the same small, remote island (Plakida): the largest Podarcis erhardii (Lacertidae) and smallest Mediodactylus kotschyi sensu lato; Gekkonidae — the two commonest insular reptiles in the Aegean Sea. The geckos of Plakida have a peculiar tail-waving behavior, documented here for the first time in this genus. We suspect that P. erhardii evolved large size to consume geckos and the geckos evolved a unique tail-waving behavior as a defensive mechanism.
TECNOLOGIAS DIGITAIS PARA CAPACITAÇÃO DE PROFISSIONAIS DE ENFERMAGEM SOBRE SEGURANÇA DO PACIENTE
Authors: Hoffmann Valeska Tais de Araújo , Sanchis Desirée Zago , Aroni Patricia , Ferreira Dêmely Biason , Godoi Valéria Rodrigues , Haddad Maria do Carmo Fernandez Lourenço
Published: August 2021

Objetivo: analisar as evidências científicas sobre o uso de tecnologias digitais para capacitação de profissionais de enfermagem sobre segurança do paciente. Método: revisão integrativa, com busca de estudos primários indexados nas bases de dados Literatura Latino-Americana e do Caribe em Ciências da Saúde, SciVerse Scopus, Cumulative Index to Nursisng and Allied Health Literature, Web of Science e Medical Literature Analysis and Tetrievel System Online, publicados em inglês, português e espanhol, sem limite de tempo. Resultados: foram selecionados 11 artigos, distribuídos entre os anos de 2008 a 2020. As tecnologias digitais desenvolvidas foram softwares, módulos de educação online, vídeos e slides, com os seguintes temas: comunicação, análise de fármacos, instrumentação cirúrgica, erros e interrupções de medicações, administração de medicamentos e infecções. e Conclusão: as tecnologias digitais utilizadas para a capacitação dos profissionais de enfermagem mostraram-se eficazes para transmissão e consolidação do conhecimento com a finalidade de proporcionar melhores práticas em saúde.
RELAÇÃO ENTRE EVENTOS TROMBÓTICOS E INFECÇÃO PELA SARS-COV-2: UMA REVISÃO DE LITERATURA
Authors: Frota Cavalcante Tahissa , Meirú de Lima Cristefânia , Ferreira José Erivelton de Souza Maciel , Rodrigues Paixão Neto Osmar , Pessoa Moreira Rafaella , Nóbrega Goularte Azevedo Viviane
Published: August 2021

Objetivo: apresentar o conhecimento produzido sobre eventos trombóticos e sua relação com a infecção pela SARS-CoV-2. Método: estudo do tipo revisão integrativa da literatura, realizado nos meses de maio e junho de 2020, em quatro bases de dados/bibliotecas virtuais/portais e buscadores acadêmicos, com as seguintes palavras-chave: coronavírus, SARS and thrombus (Pubmed, Cochrane and Science Direct) e Vírus da SARS and Transtornos da Coagulação Sanguínea (Biblioteca Virtual da Saúde). Após a busca, foram encontrados 263 estudos e com o emprego dos critérios de inclusão e exclusão restaram 59 trabalhos. Resultados: os trabalhos mostraram que as chances de ocorrência de eventos trombóticos aumentam em pessoas mais idosas e com comorbidades. Além disso, os eventos trombóticos mais prevalentes nos pacientes acometidos pela doença foram trombose pulmonar microvascular, tromboembolismo venoso de membros inferiores, síndrome coronariana aguda e acidente vascular cerebral. A avaliação e acompanhamento de pacientes, principalmente os internados em Unidade de Terapia Intensiva, no tocante ao seu estado inflamatório e os seus marcadores de hipercoagulabilidade são importantes para a detecção precoce e tomada de decisão para a administração de terapias anticoagulantes. A enfermagem é primordial para o acompanhamento e monitoramento desses pacientes. Considerações finais: embora a incidência dos eventos trombóticos em pessoas com COVID-19 em âmbito mundial já esteja melhor descrita na literatura, ainda é necessário que se produzam mais estudos clínicos e epidemiológicos para melhor explicar essa relação; é importante ainda para que se possa determinar se de fato essa doença pode ser classificada como pertencente ao grupo de doenças vasculares.
Sistematização da Assistência de Enfermagem
Authors: Souza Érika de Almeida Leite da Silva Teixeira de , Santos Edna Ferreira , Nóbrega Luiz Leonardo Louzada
Published: August 2021

Este estudo é um relato de experiência que tem como objetivo descrever a proposta de adaptação da Sistematização da Assistência de Enfermagem (SAE) para a Atenção Primária à Saúde (APS).  Foram realizados grupos de discussão com enfermeiros no período de dezembro de 2018 a março de 2019, utilizando a metodologia da SAE, tendo como referência a Resolução Cofen 358/2009, articulada com a Construção Social da APS.  A discussão foi estruturada considerando-se como eixos: a articulação da SAE com a construção social da APS; a definição dos métodos, os processos de pessoal e os instrumentos da SAE na APS.  Foi construído o projeto SAE na APS fundamentado em teorias, para implementar as mudanças no cotidiano das ações articulando os macro e microprocessos da APS com o cuidado orientado pelo Processo de Enfermagem (PE), descrito na Coleta de dados, Diagnóstico, Planejamento, Implementação e Avaliação.  O dimensionamento, a organização da escala, a capacitação na realização das atividades, procedimentos e a elaboração e estruturação de documentos, registros técnico-administrativos e assistenciais  potencializaram a enfermagem no nível local.  Dentre os desafios destacou-se a necessidade de construir materiais que possam ser replicáveis nas capacitações para a implantação da SAE, de estruturação do registro do PE no Prontuário Eletrônico e de padronização de uma taxonomia para codificar os diagnósticos de enfermagem.  A apreensão desses conceitos pela equipe provocou inquietações  capazes de gerar novos conhecimentos para induzir adequações da SAE na APS.
Cuidados de enfermagem à pessoa em cuidados paliativos com ferida neoplásica: revisão integrativa
Authors: Farah Nayara Costa , Do Carmo Pinto Coelho Paiva Andyara , Amorim Thaís Vasconselos , Fonseca Adélia Dayane Guimarães , Vilas Boas Tavares Amanda Tamires Drumond , Lima  Vitória Ferreira , Salimena Anna Maria de Oliveira
Published: August 2021

Objetivo: conhecer os cuidados de enfermagem a pessoa que apresenta uma ferida neoplásica no contexto da assistência paliativista. Método: revisão integrativa da literatura na qual foram consultadas as bases de dados CINAHL, MEDLINE/Pubmed, LILACS e SCIELO, norteada pela questão: quais os cuidados de enfermagem a pessoa que apresenta uma ferida neoplásica no contexto da assistência paliativista? Resultados: no cuidado de enfermagem a pessoa com ferida neoplásica, observou-se que as produções científicas deram maior ênfase ao manejo de feridas, incluindo técnica de limpeza, controle do odor e da dor, coleta de material para cultura e a escolha da cobertura. Revela-se escassa a produção do conhecimento acerca do apoio aos familiares e da comunicação terapêutica. Conclusão: o enfermeiro detém o conhecimento científico para tomar decisões e traçar escolhas terapêuticas para melhor assistir, no entanto o profissional deixa de perscrutar o aspecto emocional, social e espiritual, não incorporando no plano de cuidados uma abordagem integral.
EDUCAÇÃO EM SAÚDE COM CUIDADORES INFORMAIS DE PESSOAS IDOSAS COM DOENÇA DE ALZHEIMER: PESQUISA-AÇÃO
Authors: Oliveira De Albuquerque Thaynara Maria , Soares Daniele Pereira , Alves Barbalho Isabela Lunara , Fernandes Marcelo Costa
Published: August 2021

Objetivo: descrever a educação em saúde com cuidadores informais de pessoas idosas com doença de Alzheimer. Método: trata-se de estudo descritivo com abordagem qualitativa, embasado na pesquisa-ação, realizado com 15 cuidadores informais do município de São José de Piranhas, Paraíba, Brasil. Para a coleta de dados foi utilizada entrevista semiestruturada, após a aprovação do Comitê de Ética e Pesquisa. Utilizou-se do Discurso do Sujeito Coletivo para organização e análise dos resultados. Resultados: Observou-se que as metodologias ativas utilizadas proporcionaram espaço de troca de conhecimentos, além de modificar a percepção do cuidador sobre a Doença de Alzheimer. Considerações finais: é necessário promover a educação aos cuidadores buscando sanar as principais dificuldades em relação ao cuidado, proporcionando a ressignificação do cuidado a pessoa idosa com Doença de Alzheimer.
PROMOÇÃO DO CUIDADO FAMILIAR AO NEONATO COM ESTOMIA INTESTINAL:
Authors: De Lima Machado Bandeira Larissa , Firmino Silva Joana Weslayne , Rodrigues Alves de Sousa Adriana , De Moura Carvalho Marcelo
Published: August 2021

OBJETIVO: o presente estudo tem como objetivo realizar um levantamento em bancos de dados buscando identificar as estratégias de enfermagem para promoção do cuidado familiar do neonato com estomia intestinal. MÉTODO: trata-se de uma revisão do tipo integrativa de literatura, realizada durante os meses de fevereiro e março de 2021. O levantamento de dados foi realizado por meio da busca avançada na PubMed e na Biblioteca Virtual em Saúde (BVS), nas bases de dados: MEDLINE, LILACS, BDENF e IBECS. Inicialmente obteve-se 146 artigos avaliados pela elegibilidade. RESULTADOS: aplicados os critérios de inclusão e exclusão resultaram 07 artigos para análise. No que diz respeito as estratégias, dois (28,5%) dos estudos selecionados citam as cartilhas educativas e dois (28,5%) citam os vídeos educativos como estratégias educacionais para promoção do cuidado familiar. Entretanto, também foram citados as redes sociais de apoio, instruções escritas e reuniões regulares de ensino para família, além de um programa educativo focado no cuidado ao paciente com estomia. CONSIDERAÇÕES FINAIS: as estratégias evidenciadas mostraram-se eficazes para garantir o preparo e autonomia dos pais para o cuidado e consequentemente o bem estar dos pacientes.
repercussões das condições crônicas de saúde na família
Authors: Simon Bruna Sodré , Garcia Raquel Pötter
Published: August 2021

A transição demográfica e epidemiológica no Brasil tem demonstrado uma redução no quantitativo de condições agudas de saúde e elevação nas condições crônicas. Essas, em sua maioria, são imprevisíveis, apresentam progressão lenta, multicausalidade e potencial para perda funcional com o decorrer do tempo. Nossas vivências e experiências, enquanto enfermeiras, docentes e pesquisadoras, corroboram para o entendimento de que as condições crônicas de saúde têm repercussões na família. Essa perspectiva vai ao encontro da compreensão de família como um sistema, formado por subsistemas individuais, correspondentes aos seus membros e, por um suprassistema, representado pelas relações de amizade,  de trabalho e demais componentes da sociedade com os quais interagem.
Open field mirror test as a tool for the assessment of visual functions in rats with streptozotocin-induced diabetes
Authors: Sadikan Muhammad Zulfiqah , Abdul Nasir Nurul Alimah , Iezhitsa Igor , Agarwal Renu
Published: August 2021

To evaluate the use of mirror test in an open field arena as a visual function assessment tool in a rodent model of diabetes. Male Sprague-Dawley rats were divided into diabetic rats, that received intraperitoneal streptozotocin (55 mg/kg body weight) for induction of diabetes, and control rats that similarly received citrate buffer. Rats with a blood glucose level of more than 20 mmol/L were considered diabetic. Blood glucose was monitored weekly throughout the experimental period. General behavioural assessment of the rats was done at week 12 post-induction using open field arena, followed by visual-behavioural assessment with mirror and reversed mirror added in the arena. Subsequently, rats were euthanised and subjected to haematoxylin and eosin staining (H&E) staining to assess changes in retinal morphology. In the open field test, diabetic rats showed a lesser number of zone crossings (3.73-fold, p<0.001), total distance travelled (2.02-fold, p<0.001), number of rearing episodes (2.22-fold, p<0.001) and number of grooming episodes (4.33-fold, p<0.01) but a greater number of freezing episodes (2.47-fold, p<0.001) and number of the faecal pellet (4.17-fold, p<0.01) compared to control rats. Control rats spent more time with higher zone entries toward mirrored than non-mirrored and reversed mirror zones (p<0.05 and p<0.01 respectively), whereas diabetic rats showed no preference for zones.  Normal rats also showed higher freezing episodes within the mirrored zone compared to diabetic rats (2.00-fold, p<0.05). The retinal morphometry showed significant thinning of various retinal layers in the diabetic group compared to control rats. Visual behavioural activities of diabetic rats in an open field arena with the presence of a mirror could detect the presence of visual loss. Changes in visual functions positively correlated with changes in retinal morphology. Therefore, an open field mirror test could be used as an alternative for assessing visual function in the rodent model of diabetes.
Socio-Political Imaginings of the Kolkata Maidan
Authors: Pal Shreyasi
Published: September 2021

The legacy
of colonial spatial hegemony in Kolkata is investigated here with focus on the idea of public space particularly, the open maidan, defined by predominantly colonial buildings. This former
centrepiece of British spatial expression of authority and pomp is appropriated
by diverse uses but the edges can be read as a built record of the city’s tryst
with colonial rule for 200 years. Evolving from a strictly Palladian palette to
a more accommodating Imperial Indo-Saracenic, the continuity of colonial
vocabulary is only rarely broken by modern buildings. Parallel situations in
other British colonies e.g. the padang
in Singapore, have undergone considerable redefinition and re-articulation,
often consciously undermining the erstwhile hegemonic position. The paper would
trace the ambivalent image of the maidan
over the years, to uncover, albeit partially, the patterns to which the
colonial, post-colonial and even the neo-liberal State limits itself in
imagining this heterogeneous space.

The
evolving socio-political imagination of the maidan
and in that the cityscape would be traced on the basis of how media has
captured it at critical historical junctures, the samples varying across time
and across media. Maidan as a backdrop of riots, rallies
and atrocious human sufferings in the wake of the Partition of India would be
captured from newspaper clippings and narratives. Post-independence nation
coming to terms with modernization and subsequent characterization of the maidan as a site for civic unrest, a
first of a kind public space for sports clubs, picnics, fairs- an embodiment of
personal freedom- the urban other- would be understood from stills from
Satyajit Ray’s Apu Trilogy and the Calcutta Trilogy. The attempt here would be to look for broader
patterns of postcolonial urbanism by specific focus on evolving socio-political
re-imaginings of colonial urban public spaces.
Possibilities of prognosis and improvement of treatment results in children with congenital malformations of the gastrointestinal tract
Authors: Budarova K. V. , Shmakov A. N. , Chekanov M. N. , Vereshchagin E. I. , Peshkova I. V. , Polyakevich A. S.
Published: September 2021

The category of newborns with congenital malformations is considered the most difficult to treat. The influence of “stress”factors on the body in a short period of time triggers a pathogenetically determined chain reaction that leads to the development of multiple organ failure syndrome. The forecasting methodology determines the timeliness and directions of intensive care to approach and achieve positive results in this group of patients.

The aim of the study: is to show the diagnostic and practical value of metabolic markers and functional indicators of homeokinesis in newborns with congenital malformations of the gastrointestinal tract.

Materials and methods. An observational study of 81 patients in the neonatal period. The prognostic assessment of functional parameters and biochemical markers was performed by ROC analysis.

Results. In newborns with malformations of the gastrointestinal tract, the course of the pre-and early postoperative period is associated with cardiopulmonary maladaptation, which requires the protection of vital functions. By the end of the first week, priority is given to therapy aimed at restoring the motility of the gastrointestinal tract. The prognostic value of the adverse outcome was determined: stress index greater than 3503 Sp = 98.36% (95%CI 86.3–99.2) and Se = 99.2% (95%CI 87.3–100), lactatemia level greater than 3.3 mmol/L Sp = 73.7% (95% CI 59.6–84.7) and Se = 93.6% (95% CI 78.9–100). The control of the infectious process and the selection of antibacterial therapy is important, since the risks of developing septic shock are high. Prolonged epidural analgesia is the optimal method of analgesia and is indicated in suspected cases of failure to achieve 75% of the volume of enteral nutrition by the week of the postoperative period Sp 85.42% (95%CI 48.2–97.7), Se 46.8% (95% CI 62.0–84.2).

Conclusions. Prognostic models allow predicting the outcome of critical conditions and timely adjusting the volume of therapy.
The Effect of Quartet Card Learning on Semantic Memory of SD Unggulan Puri Taman Sari Makassar
Authors: Riszky Muhammad , Rahmah Mutmainnah Nur , Sari Adlia Julia , Silmi Ismi Shahriani
Published: September 2021

Penelitian ini bertujuan untuk menunjukkan pemberian media pembelajaran kartu kuartet mempengaruhi memori semantik siswa sekolah dasar (SD) dengan menggunakan dua variabel, variabel bebas yaitu media pembelajaran kartu kuartet dan variabel terikat yaitu memori semantik. Isi dari materinya yaitu berisi mengenai budaya yang ada di Sulawesi Selatan yang dibagi menjadi delapan aspek terdiri dari pahlawan, tempat wisata, kuliner, pakaian adat, alat musik, rumah adat, permainan, dan seni tari. Rancangan penelitian ini merupakan eksperimen dengan menggunakan rancangan randomized two group design. Partisipan dalam penelitian ini terdiri dari 24 siswa kelas 4 SD yang dibagi menjadi dua kelompok yang terdiri dari kelompok eksperimen yang menggunakan media pembelajaran kartu kuartet dan kelompok kontrol yang menggunakan metode ceramah. Penggunaan media pembelajaran kartu kuartet memiliki pengaruh lebih besar dalam memori semantik dibandingkan dengan memori ceramah. Berdasarkan uji statistic melalui SPSS, diperoleh skor rata-rata kelompok eksperimen sebesar 12.750 dan skor rata-rata kelompok kontrol sebesar 8.166. Berdasarkan uji independent sample t-test melalui SPSS diperoleh nilai p=0.000. Nilai p<0.050 menunjukkan bahwa hasil signifikan dan hipotesis diterima, maka terdapat perbedaan memori semantik antara kelompok individu yang menggunakan media pembelajaran kartu kuartet dibandingkan metode ceramah. Penelitian ini menyimpulkan bahwa kegiatan dengan menggunakan metode pembelajaran kartu kuartet dapat meningkatkan hasil belajar siswa dibandingkan dengan metode pembelajaran ceramah.
Differential expression of patched domain-containing 1 in human epithelial ovarian cancer.
Authors: Mamoor Shahan
Published: September 2021

Epithelial ovarian cancer (EOC) is the most lethal gynecologic cancer (1). We performed discovery of genes associated with epithelial ovarian cancer and of the high-grade serous ovarian cancer (HGSC) subtype, using published microarray data (2, 3) to compare global gene expression profiles of normal ovary or fallopian tube with that of primary tumors from women diagnosed with epithelial ovarian cancer or HGSC. We identified the gene encoding patched domain-containing 1, PTCHD1, as among the genes whose expression was most different in epithelial ovarian cancer as compared to the normal fallopian tube. PTCHD1 expression was significantly lower in high-grade serous ovarian tumors relative to normal fallopian tube. PTCHD1 expression correlated with progression-free survival in patients with p53 mutant ovarian cancer. These data indicate that expression of PTCHD1 is perturbed in epithelial ovarian cancers broadly and in ovarian cancers of the HGSC subtype. PTCHD1 may be relevant to pathways underlying ovarian cancer initiation (transformation) or progression.
Differential expression of LIM domain binding 3 in human epithelial ovarian cancer.
Authors: Mamoor Shahan
Published: August 2021

Epithelial ovarian cancer (EOC) is the most lethal gynecologic cancer (1). We performed discovery of genes associated with epithelial ovarian cancer and of the high-grade serous ovarian cancer (HGSC) subtype, using published and public microarray data (2, 3) to compare global gene expression profiles of normal ovary or fallopian tube with that of primary tumors from women diagnosed with epithelial ovarian cancer or HGSC. We identified the gene encoding LIM domain binding 3, LDB3, as among the genes whose expression was most different in epithelial ovarian cancer as compared to the normal fallopian tube. LDB3 expression was significantly lower in high-grade serous ovarian tumors relative to normal fallopian tube. LDB3 expression correlated with progression-free survival in patients with ovarian cancer. These data indicate that expression of LDB3 is perturbed in epithelial ovarian cancers broadly and in ovarian cancers of the HGSC subtype. LDB3 may be relevant to pathways underlying ovarian cancer initiation (transformation) or progression.
Blood donation narratives on social media
Authors: Ramondt Steven , Merz Eva-Maria , Kerkhof Peter
Published: September 2021

Social media have shown great potential for producing significant changes in behavior and have become the cornerstone for many public health and agency efforts. The nonprofit sector -including blood collection agencies- has adopted social media to aid their cause and reach their goals. However, despite the tremendous impact of social media on society and its promising role for donor recruitment and retention, it has been overlooked in donor research. This study therefore sought to map the social media landscape around blood donation. We showcase an inductive computational method to make sense of vast amounts of dynamic unstructured blood donation text data that exists on social media. With this method, we display what is discussed about blood donation on social media, how these topics are distributed on Facebook and Twitter, and how the prevalence of these topics changes over time. We applied structural topic modeling on 7 years of Dutch blood donation Facebook and Twitter data by the general public. We found 25 topics clustered in 6 distinct clusters. Over time, there is a substantial reduction of messages in which donors announce their donations. Topics that emphasize the positives of blood donation, including donor identity-related topics, are rising. In addition, the findings show a clear social media platform contrast. Topics related to campaigns and controversial policies were found more on Twitter and positive donation topics and topics related to the donation process more on Facebook. To make optimal use of social media for recruitment and retention campaigns and efforts, blood collection agencies should recognize the turbulent environment in which they take place. Monitoring public opinions about blood donation will help blood collection agencies make strategic choices and utilize social media more effectively.
CD36 is differentially expressed in the tumors of breast cancer patients treated with trastuzumab.
Authors: Mamoor Shahan
Published: September 2021

Trastuzumab (Herceptin) is a monoclonal antibody targeting the extracellular domain of the human epidermal growth factor receptor 2 (HER2) (1) utilized for the treatment of adjuvant and metastatic breast cancer (2) in the United States and worldwide. We mined published microarray data (3, 4) to discover in an unbiased manner the most significant transcriptional changes associated with trastuzumab treatment. We identified the scavenger receptor CD36 as among the genes most differentially expressed in the primary tumors of patients with breast cancer treated with trastuzumab. A single dose of trastuzumab was sufficient to result in differential expression of CD36 in the primary tumors of patients with breast cancer, suggesting that transcriptional induction of CD36 is a direct result of trastuzumab administration.
Real Concerns over COVID-19 Variants of Concern
Authors: Hatem  , El Ridi Rashika
Published: September 2021

Severe acute respiratory syndrome corona virus (SARS-CoV)-2 obtained from patients infected despite being fully vaccinated with either BNT162b2 (Pfizer/BioNTech), mRNA-1273 (Moderna), or JNJ-78436735 (Janssen) showed increased mutations rates in the N-terminal domain (NTD) and receptor-binding domain (RBD) of the spike glycoprotein when compared with virus from unvaccinated controls (1). These changes are associated with immune evasion and diagnostic failures, prominent characteristics of variants of concern (2). Variants of concern (VOC) appeared to be overrepresented in numerous breakthrough infections of fully vaccinated people in the United States and (1, 3-6), and Israel (7). These findings confirm concerns about the relation of SARS-CoV-2 variants with vaccine breakthrough, and urged us to attempt clarifying the likely link between vaccination with the currently used vaccines and VOC emergence.
Distinguishing Interpersonal and Ideological Prosociality: Introducing the Construct of Ideological Prosociality
Authors: Nezlek John B.
Published: September 2021

Prosociality refers to dispositions and behaviors intended to benefit others, and the present study assumed that these dispositions reflect people’s values. Much of the research on prosociality has examined prosociality in what can be called the interpersonal domain, e.g., helping others. I propose that prosociality also exists in the ideological domain. People hold prosocial values that concern collectives, not specific individuals. Multilevel analyses of data collected in Wave 8 of the European Social Survey (44,000 respondents in 23 countries) found positive relationships between ideological prosocial values and attitudes toward immigrants, refugees, and gays and lesbians, attitudes about the environment and climate change, social benefits, and income equality. Moreover, these relationships remained significant after controlling for participants’ sex, age, income, education, political orientation, and happiness. In contrast, relationships between these attitudes and interpersonal prosocial values were either negative or not significant.
Teacher Mindsets and Student Sense of Classroom Belonging
Authors: Pyne Jaymes , Grodsky Eric
Published: September 2021

We investigate how teachers’ mindsets—or their beliefs about learning and school—relate to adolescents’ individual and collective reports of classroom belonging. Our pre-registered analyses of 1,200 middle school students show that teachers’ growth mindset and confidence in teaching positively relate to students’ math class belonging—explaining 40 percent of belonging among classes. Yet a teacher’s own sense of school belonging is unrelated to the belonging students feel in class. We also find that the conditional association between math teaching confidence and students’ classroom belonging is twice as strong for Black adolescents as it is for their White peers, and a teacher’s growth mindset has no bearing on Asian adolescents’ math class belonging.
Where is the evidence in evidence-based law reform?
Authors: Chin Jason , Nakagawa Shinichi , Lagisz Malgorzata
Published: September 2021

Law reform bodies frequently express a commitment to evidence-based law and policy recommendations. They also readily endorse the importance of the transparency and democratization of their processes. They do not, however, connect these two goals of evidence-based policy and transparency. This stands in contrast to the ongoing revolution in several fields of research towards open science and synthesis, which envisions transparency and open access as a means to improve the reliability of science. In this article, we suggest that several recent concerns and controversies surrounding evidence-based law reform, such as allegations of bias among officials, can be addressed through open science and synthesis. We include a novel study of 22 research syntheses commissioned by the Royal Commission into Institutional Responses to Child Sexual Abuse, finding uneven adoption of even the most basic transparency measures. We end with five proposals that advance transparent evidence-based law reform, including law reform bodies requiring that commissioned reports follow basic reporting guidelines and greater disciplinary diversity among law reform staff.
Oxidized Mantle Sources of HIMU and EM-type Ocean Island Basalts
Authors: Nicklas Robert , Hahn Rachel , Willhite Lori , Jackson Matthew , Zanon Vittorio , Arevalo Jr. Ricardo , Day James
Published: September 2021

Oxygen fugacity (fO2) is a fundamental variable in igneous petrology with utility as a potential tracer of recycled surficial materials in the sources of mantle-derived lavas. It has been postulated that ocean island basalts (OIB) have elevated fO2 relative to mid-ocean ridge basalts (MORB) owing to more oxidized source regions. To clarify this issue, trace-element systematics of olivine grains are reported from OIB lavas with HIMU (high-; Mangaia, Canary Islands), enriched mantle (EM; Samoa; São Miguel, Azores Islands) and depleted MORB mantle (DMM; Pico, Azores) Sr-Nd-Pb-Os isotopic signatures, to constrain the fO2 of each magmatic system. Despite sampling distinct mantle reservoirs based on radiogenic isotope systematics, these OIB suites show similar fO2, ranging from +1.5 to +2.9 FMQ, with an average of 2.0 ± 0.7 FMQ, significantly higher than MORB at +0.6 ± 0.2 FMQ using the same oxybarometer. OIBs show no correlation between fO2 and bulk rock isotopic ratios or parental magma compositions. The lack of correlations with isotopic signatures likely results from radiogenic isotope signatures being hosted in volumetrically minor trace element enriched mantle lithologies, while fO2 reflects the volumetrically dominant mantle component. Higher fO2 in OIB relative to MORB implies a uniformly oxidizing plume source mantle that may be the result of either a common oxidized oceanic crust-rich reservoir parental to all modern plume lavas, or preservation of un-degassed and oxidized mantle domains formed early in Earth history.
The Myth of When and Where: How False Assumptions Still Haunt Theories of Consciousness
Authors: Rahimian Sepehrdad
Published: August 2021

Recent advances in Neural sciences have uncovered countless new facts about the brain. Although there is a plethora of theories of consciousness, it seems to some philosophers that there is still an explanatory gap when it comes to a scientific account of subjective experience. In what follows, I will argue why some of our more commonly acknowledged theories do not at all provide us with an account of subjective experience as they are built on false assumptions. These assumptions have led us into a state of cognitive dissonance between maintaining our standard scientific practices on one hand, and maintaining our folk notions on the other. I will then end by proposing Illusionism as the only option for a scientific investigation of consciousness and that even if ideas like panpsychism turn out to be holding the seemingly missing piece of the puzzle, the path to them must go through Illusionism.