bluuebunny/crossref_metadata_2025 huggingface dataset:
Fetal growth restriction: features of somatomental development in infancy
Authors: Dolgova N S , Yavorskaya S D
Published: May 2018

Aim. To determine the features of physical and somatic health of full-term infants with fetal growth restriction during the first year. Methods. A retrospective analysis of 100 neonatal medical records of full-term infants was performed. All children were divided into 2 groups: group 1 - full-term infants, who were diagnosed with fetal growth restriction at birth (n=50), group 2 - full term infants born with normal body weight (n=50). Control points of comparison were neonatal period, months of life 1, 3, 6 and 12. Overall anthropometric data (length, weight, head and chest circumference), incidence and structure of morbidity and child's key system involvement were assessed. Results. Full-term newborns with fetal growth restriction present a risk group of growth and weight gain retardation during infancy, perinatal disorders of central nervous system persistent in 28±12% of cases by year 1 and, consequently, restriction of psychomotor (16±10%) and pre-verbal development (16±10%). Full-term low birth-weight newborns are characterized by short period of breast feeding and are included into the group of frequently ill children. The most vulnerable system, except for central nervous system, is the respiratory system. Conclusion. Children born with fetal growth restriction by the full term of gestation require special approach: diagnosis of and degree of central nervous system perinatal disorders at the first minutes of life, dynamic monitoring and personalized rehabilitation and preventive measures during the first year of life.
Investigation of the correlation of allele polymorphism of renin-angiotensin system genes, nitric oxide synthase and folate cycle with the severity of ischemic stroke
Authors: Levashova O A , Baranova N I , Zolkornyaev I G
Published: May 2018

Aim. To study the frequency of polymorphic gene variants encoding proteins of renin-angiotensin system [AGT Thr174Met (rs 4762), AGT Met235Thr (rs699), AGTR1 A1166C (rs5186)], endothelial factors [NOS3 C786T (rs2070744)], and folate cycle enzymes [MTHFR C677T (rs1801133)] in patients with various ischemic stroke severity. Methods. 98 patients with ischemic stroke verified by magnetic resonance imaging and computed tomography scan of the brain, were examined. The severity of stroke was assessed by National Institutes of Health Stroke Scale. The allelic variants of genes were typified by polymerase chain reaction with the detection of amplification products in the «real time» mode. Results. The analysis of genetic polymorphism frequency of renin-angiotensin system did not reveal statistically significant differences in the study groups. The polymorphism of NOSC786T gene in the study was also not associated with the severity of ischemic stroke. Among the studied polymorphic variants, only the C677T polymorphism of MTHFR gene was revealed to be reliably associated with severe course of acute cerebral ischemia. Conclusion. C677T polymorphism of MTHFR gene is reliably associated with severe course of acute cerebral ischemia; carriage of 677T allele of MTHFR gene in the studied category of patients can cause an increased level of homocysteine and have an adverse effect on the course of acute cerebral ischemia.
Modification of biochemical recurrence risk in patients with localized prostate cancer after radical prostatectomy with combined histomorphological changes in the peritumoral zone
Authors: Bova F S , Kit O I , Maksimov A Yu , Karnaukhov N S
Published: May 2018

Aim. To assess the prognostic significance of histopathological processes in the peritumoral zone with respect to the risk of biochemical recurrence in patients with localized prostate cancer after radical prostatectomy. Methods. Histomorphological studies were conducted in the perifocal area of surgical tissue samples from 309 patients with localized prostate cancer (T1c-2cN0M0) after a radical surgery using light microscopy. Four groups of patients were identified depending on the risk of recurrence. Enzyme immunoassay was used to determine the concentration of prostate-specific antigen in the serum at baseline and every 3 months for two years after the surgery to detect biochemical recurrence. Results. Histomorphological examination of the peritumoral zone made it possible to identify histopathological processes associated with adenocarcinoma in 257 out of 309 (83.2%) patients with localized prostate cancer. The risk of biochemical recurrence of a combination of prostatic adenocarcinoma and prostatic intraepithelial neoplasia-2 increased by 3.3 (p=0.02), and of a combination of adenocarcinoma, neoplasia and chronic inflammation in the perifocal zone increased by 4.5 times (p=0.005) compared to patients without histopathological changes of the peritumoral zone. In combination of prostate adenocarcinoma with neoplasia and chronic inflammation in the peritumoral zone, the number of patients with an intermediate risk of cancer recurrence after surgical treatment increased due to decrease of the proportion of patients with very low and low risk of recurrence of the oncologic disease. Conclusion. The combination of prostate cancer with high-grade prostatic intraepithelial neoplasia and chronic inflammation in the peritumoral zone modifies the risk of biochemical recurrence of cancer after radical prostatectomy.
DNA-cytometric characteristics of recurrent soft tissue sarcomas
Authors: Nepomnyashchaya E M , Ul'yanova E P , Novikova I A , Selyutina O N , Zlatnik E Yu , Aliev T A , Vashchenko L N , Ausheva T V , Andreyko E A , Zolotareva E I , Bondarenko E S
Published: May 2018

Aim. To determine the content of deoxyribonucleic acid (DNA) and distribution of cells in mitotic phases in patients with recurrent soft tissue sarcomas for the assessment of malignancy of the process. Methods. Tumor tissues of patients with recurrent soft tissue sarcomas were studied. Research methods included histological, DNA-cytometric and statistical methods. Results. Proliferative activity and proliferative index of recurrent sarcomas differed depending on the tumor grade and stage. Differences in the number of diploid, aneuploid and polyploid cells were determined in each group and between the groups depending on the cell cycle phases. Cell cycle parameters were as following: 100% of G1 (well-differentiated) cancer were diploid, as well as 33.3% of G2 (moderately differentiated) and 15% of G3 (poorly differentiated) tumors. Aneuploid tumors prevailed in G2 and G3, the ratio of which was 66.7 and 85%, respectively. The analysis of kinetic parameters of the cell cycle allowed establishing a decrease in the number of cells in G1/G0 phase of the cell cycle from G1 to G3, which was accompanied by a statistically significant increase in the proportion of cells in S-phase (p ˂0.05). Conclusion. The DNA-cytometric study of cell cycle parameters showed high biological potential of recurrent soft tissue sarcomas, which was determined by two indices - the proportion of cells in G2+M-phase and the cell loss factor; 100% of well-differentiated (G1) tumors, 33.3% of moderately differentiated (G2) and 15% of poorly differentiated (G3) tumors were diploid; aneuploid tumors prevailed in G2 and G3.
Estimation of serological landscape of nazofaringeal strains of Streptococcus pneumoniae circulating in the territory of Barnaul
Authors: Kozyanova Yu A , Safyanova T V
Published: May 2018

Aim. To study the prevalence of S. pneumoniae serotypes in nasopharyngeal carriage among different age groups in organized groups to optimize the information and analytical system of epidemiological surveillance of pneumococcal infection. Methods. By classical bacteriological method 75 nasopharyngeal isolates of pneumococcus, which later were serotyped, were identified in 319 subjects of different age from children's and adults' organized groups in Barnaul. Results. In 2017 the epidemiological screening was used to evaluate the prevalence of S. pneumoniae carriage. After identification, nasopharyngeal pneumococcal strains underwent serotyping. The greatest proportion of serological landscape of the studied strains was 3 and 19F serotypes, the total proportion of which was 75±9.7%. 13-valent pneumococcal conjugated vaccine had the maximum coverage of local strains - 62.5%. Based on the data on community-acquired pneumonia caused most often by pneumococcus, from information and analytical system received from the territories of the region, the database «Community-acquired pneumonia of the Altai Krai» was created. However, for an adequate assessment of the epidemiological situation regarding pneumococcal infection in the region, incoming information was not enough. The analysis of information from the territories on community-acquired pneumonia allowed identifying disadvantages of epidemiological surveillance of this nosology and inability to adequately assess the epidemiological situation with regard to pneumococcal infection in the region. Conclusion. The results of serotyping allowed determining further tactics of immunization in the Altai Krai; information and analytical system requires supplementing microbiological monitoring data regarding antibiotic susceptibility and resistance to disinfectants of the etiological agent.
Effect of modified twin block appliance used for distoclusion treatment on stomatognathic system
Authors: Novruzov Z G , Alieva R K , Garaev Z I , Kulieva S K
Published: May 2018

Aim. Study of the effect of modified twin block activator used for distoclusion treatment on stomatognathic system and its improvement. Methods. 55 patients with skeletal distoclusion were examined. Out of them 28 patients treated orthodontically comprised the study group and 27 non-treated patients were included into the control group. The patients' age was 10-14 years (mean age 11.78±0.91), the duration of treatment was 1.5-2 years (mean duration 1.82±0.43). To avaluate the changes in stomatognathic system, cephalometric analysis was performed before and after treatment, and in the control group cephalometric analysis was performed with a 2-year interval. Results. During treatment with modified twin block appliance, SNB angle reached norm (80°). This is an important positive result in the treatment of distoclusion. ANB angle reflecting sagittal relationship between the upper and lower jaws and WITS decreased and reached normal size. Overjet normalized due to upper incisors retrusion and repositioning of the mandible forward in patients of the study group. In this group due to changes in soft tissues, in-profile esthetic and harmonious appearance of lips and chin was restored. In case of relative physiological rest the opened lips became closer and provided esthetic optimum of the face. Conclusion. Use of modified twin block appliance for the treatment of patients with distoclusion due to repositioning of the mandible forward allows improving sagittal relationship between the upper and lower jaws as well as overjet correction without increasing face height; use of modified twin block appliance allows normalizing sagittal occlusion and protrusion of upper incisors and upper lip.
Neurological status and ethanol preference in rats during alcohol addiction formation
Authors: Tarasov A S , Knyshova L P , Morkovin E I , Yakovlev A T , Poroyskiy S V
Published: May 2018

Aim. To estimate the features of neurological status and drinking behaviour in rats during 20 days of chronic alcohol intake. Methods. The current study was performed on 40 male Wistar rats (170-300 g). The animals from the study group were administered 15% solution of ethanol used as the only fluid source. On day 20 of the experiment the alcohol preference test and evaluation of neurological status were performed: tail-suspension (to determine paresis and paralysis), home cage motion activity (to determine gait disorders and stereotypic movements) and features of horizontal beam-walking (evaluation of movement coordination) were assessed, presence of the basic reflexes (startle reflex, external auditory canal reflex, corneal reflex) was controlled. Results. The main neurological signs were presented as ataxic form, in which unsteady gait in beam-walking test was predominant. In the experimental groups, the signs of ataxic form of neurological deficit were demonstrated, when animals slipped off and fell off the beam within 40 s from the beginning of the test. This was associated with the significant increase of discrimination ratio in alcohol preference test. Conclusion. In rat models of chronic alcohol intake, significant changes in drinking behavior and alcohol preference test were found on day 20 of the experiment, reflecting formation of alcohol addiction; changes in drinking behavior were associated with mild and moderate neurological deficit, primarily including movement coordination disorders that illustrates the malfunction of peripheral nervous system.
Arterial blood supply of the umbilical region in newborns
Authors: Kivva A N , Leiga A V
Published: May 2018

The review of national and foreign literature sources presents information on arterial blood supply of the umbilical region in newborns having relevant practical significance due to the development of new surgical approaches in that part of the anterior abdominal wall. Scientific data on the course and location of arteries participating in the blood supply of the umbilical region are summarized. Particular attention is devoted to the description of superficial, superior and inferior epigastric arteries and umbilical arteries. The issues of intervascular connections between the named arteries and other blood vessels are discussed including information on various anastomosis variations and their extent. Various existing viewpoints regarding the location and depth of anastomoses between the vessels essential for blood supply of the umbilical region are presented as well as the layers, through which the main arteries pass, and the character and level of their branching. Features of arterial blood supply of the umbilical region in newborns are also noted. The paper contains data on the role of umbilical arteries in the umbilical region supply in children of that age. It is demonstrated that blood supply of the umbilical region in newborns still poses issues that are insufficiently researched and solved, such as assessing functional capacity of the umbilical arteries, revealing histotopographic peculiarities in the location of blood vessels within the layers and various segments of the umbilical region, topographic and anatomic identification of the segments that are most and least supplied with arterial vessels in that part of the abdominal wall.
Study of medico-biological, medico-social and organizational factors influencing the morbidity of school-age children
Authors: Khuzikhanov F V , Mukhametdinova A A
Published: May 2018

Aim. The study of the incidence among school-age children, and development of a complex of medico-biological, medico-social and organizational measures for improving health status of schoolchildren. Methods. Statistical, mathematical, sociological. Results. Morbidity among children in Kazan in 2015-2017 increased to 20.4%, incidence during this period increased by 38.6%. The conducted examination of physical development of schoolchildren revealed significant decrease of the ratio of students with normal physical development. While in primary school this parameter was 85.3±2.17%, in grades 8 to 11 it decreased to 77.8±1.98% (p <0.01). The social and hygienic health characteristics of schoolchildren's health include the following: 25% of surveyed students live in families with a low subsistence level; 30% of schoolchildren are brought up in single-parent families; in 10% of cases parents do not allocate money for child nutrition at school; 30.5% of schoolchildren of grades 8 to 11 smoke; 35.9% of students of grades 8 to 11 drink alcohol; 34.9% of schoolchildren have conflicts with their classmates; 17.1% of schoolchildren of grades 8 to 11 do not eat hot meals at school; 28% of students consider themselves not informed about the issues of proper nutrition, etc. The conducted study of the schedule at schools demonstrated that the workload of the junior schoolchildren exceeds the age standards by 5-7 hours, and in the middle and senior classes the load turned out to be higher than the age standards by 5-10 hours. Conclusion. One-way ANOVA reflected that medico-biological, medico-social and organizational factors significantly influence the occurrence of diseases in school-age children; based on the data on the influence of unfavorable risk factors on the development of diseases in school-age children we will develop measures for medical and social prevention.
Complicated abdominal delivery in females of the Kyrgyz Republic: a retrospective study
Authors: Samigullina A E , Vybornykh V A
Published: May 2018

Aim. The study of the dynamics of the rate of complicated abdominal delivery in the Kyrgyz Republic. Methods. A retrospective cohort study was conducted on the basis of the Kyrgyz state medical institute of retraining and advanced training of the Ministry of Health of the Kyrgyz Republic. The data of consolidated annual reports (form No. 14 «The hospital services report») of the Republican medical information center of the Ministry of Health of the Kyrgyz Republic on the number of abdominal deliveries and complicated abdominal deliveries in women of the Kyrgyz Republic in 2005-2016 were used. For the analysis of time series reflecting the change of the rate and dynamics of complicated abdominal delivery, the developmental cycle of 12 years was chosen. Medium-term prognosis of dynamics of complicated abdominal delivery was calculated till 2021 using the pair-wise linear regression equation, the equation parameters were calculated using the method of least squares. Results. The study showed the increase in the number of abdominal deliveries in the Kyrgyz Republic during 12 years by 3.2 times and the increase of complicated surgical deliveries by 11.2 times and revealed negative, strong and reliable correlation between maternal and perinatal mortality and the number of abdominal deliveries. A two-fold increase of the rate of complicated caesarean sections in 2010 compared to 2009 (p <0.001), a decrease of this parameter in 2011-2012 by 1.8 times (p <0.001) and subsequent increase by 3.1 times from 2013 to 2016 (p <0.001) were revealed. The leading place in the rate of complicated caesarean sections is taken by Bishkek and Osh region, where the institutions of tertiary medical care are located and severe obstetric and extragenital pathology is concentrated. The medium-term prognosis for the dynamics of complicated abdominal deliveries calculated till 2021 indicates the continued increase of this parameter. Conduction. The obtained results demonstrate the need for thorough study of this problem with revision and organization of information logistics to reveal a real state and determine cause-and-effect factors influencing these parameters.
The value of hysteroscopy for diagnosing pathology of the uterine cavity in the postpartum period
Authors: Ampilova E A , Klyucharov I V , Morozov V V , Galimova I R , Khasanov A A
Published: May 2018

Although hysteroscopy is considered a gold standard of diagnosis and treatment of different pathologies of uterine cavity and the postpartum period is not considered to be a contraindication to hysteroscopy, the study of the state of the uterus after delivery with the use of hysteroscopy is not common. We propose that hysteroscopy is a valuable diagnostic method in the postpartum period, potentially reducing the risk of postpartum complications. The article presents a brief literature review regarding the role of hysteroscopy in the diagnosis of uterine pathology in the postpartum period. The following effects of hysteroscopy on the postpartum uterus are observed: mechanical effect of fluid flow on the wall of the uterus increases contractility, provides washing out of the uterine cavity (blood clots, decidual tissue) and reduction of the number of bacteria (bactericidal effect of antiseptics). Indications for hysteroscopy in the postpartum period are presented. Hysteroscopic picture in the normal course of the postpartum period is described, as well as in such pathological conditions as uterine subinvolution, endometritis (after vaginal delivery and delivery by cesarean section) and placentation abnormalities. The technique of hysteroscopy in the postpartum period is described, which has some significant differences from traditional hysteroscopy. Photos of the uterine cavity one month after cesarean section are presented. Pathologies of the uterine cavity in the postpartum period are a subject that require further investigations not only by traditional non-invasive visualization techniques, but also by modern minimally invasive endoscopic technologies. Hysteroscopic visualization of the uterine cavity allows confirming the diagnosis and, if needed, accurately performing of the necessary intervention with minimal risk of intra- and postoperative complications.
Capabilities of computed tomography angiography in the diagnosis of coronary artery calcifications in patients with rheumatoid arthritis
Authors: Sultanova M Dzh
Published: May 2018

The study was performed to identify the features of coronary artery calcifications with the use of coronary computed tomography angiography in patients suffering from rheumatoid arthritis. In the study, calcifications were found in one vessel in 5 (8.3%) patients, in two vessels - in 24 (40%) subjects, in three vessels - in 28 (46.7%), and in four vessels - in 3 (5%) patients. 100% of patients were diagnosed with calcifications in the left descending artery, 90.2% - in left circumflex artery, 56.9% - in right coronary artery, 9.8% - in the root of left coronary artery, 92.2% of patients were diagnosed with calcifications of the aortic arch. The highest calcium score was registered in left circumflex artery (343.5±10.0 HU), and the lowest one - in right coronary artery (262.1±17.7 HU). The study results demonstrated correlation between the stage of rheumatoid arthritis and coronary calcification. In 77.8% of patients with stage I of the disease and in all patients with stage II, III and IV, calcifications of various size and localization were revealed in coronary arteries and aortic arch. Also, the relationship between duration of the disease and calcinosis extent was revealed. The obtained results indicate the importance of coronary computed tomography angiography for the diagnosis of coronary atherosclerosis in patients with rheumatoid arthritis due to high risk of cardiovascular complications in these patients.
Some aspects of legal regulation of medical secrecy in the Russian Federation
Authors: Khamitova G M , Khamitova D V
Published: May 2018

Aim. To propose the development of a new form of informed voluntary consent, taking into account the legal regulation of medical secrecy. Methods. When performing the study, analytical method was used. The analysis of the mechanism of obtaining information about the patient was performed, including the study of a number of laws governing the transfer of information to the third parties without the patient's consent. Results. It was found that the patient's relatives can not be provided with information about the course of the disease and its treatment, unless the patient has previously signed a voluntary consent to transfer the information. The basis for such refusal is Article 13 of Federal Law No. 323-FZ issued on November 21, 2011 (as amended on July 29, 2017) «On the Fundamentals of Health protection of Citizens in the Russian Federation», which establishes the conditions under which information about patient's health can be transferred. This article examines the problem of violation in the field of disclosure of medical secrets, as well as the rights of patient's close relatives to obtain information about his or her state of health. The need to refine the mechanisms of obtaining information, which is a medical secret, is revealed and justified. Conclusion. Based on the review of laws regulating the procedure of information transfer, the authors propose the development of a new form of consent for disclosure of the patient's information about his state of health, which must necessarily be provided to the patient when contacting a medical organization, which in the future will significantly simplify the legal doctor-patient relationships.
Pengaruh Lama Perebusan Jagung (Zea mays. L) dengan Penambahan Konsentrasi CaCO3 pada Emping Jagung
Authors: Widyasanti Asri , Nurjanah Safira
Published: May 2018

Emping jagung merupakan salah satu produk olahan biji jagung yang memiliki nilai jual yang tinggi. Namun dalam proses pembuatan emping jagung terdapat beberapa kendala yaitu menghilangkan perikap dan tipcap dari biji jagung. Perikap dan tipcap emping jagung dapat dihilangkan dengan cara perebusan dengan penambahan CaCO3. Penelitian ini bertujuan mengetahui pengaruh lama perebusan dan konsentrasi CaCO3 terhadap mutu produk emping jagung. Metode penelitian yang digunakan adalah eksperimental laboratorium, Rancangan Acak Lengkap (RAL) faktorial yang diharapkan dapat memberikan informasi mengenai pengaruh lama perebusan dan konsentrasi CaCO3 yang tepat sehingga menghasilkan produk emping jagung yang baik. Perlakuan pada penelitian ini terdiri dari dua faktor yaitu lama perebusan dengan suhu 950C selama 60 menit, 90 menit dan 120 menit dan penambahan CaCO3 dengan konsentrasi 1%, 1,5% dan 2 % dari berat kering jagung dan 0% sebagai kontrol dengan dua kali ulangan. Hasil penelitian menunjukkan bahwa kombinasi perlakuan emping jagung dengan lama perebusan 120 menit dengan penambahan CaCO3 sebanyak 2% merupakan perlakuan terbaik dengan paremeter yang diamati antara lain kadar air 7,53%, kadar abu 2,26%, protein 8,72%, kadar lemak 3,20%, kadar karbohidrat 84,11%, Nilai Hue 74,615, rendemen total 69,9%, Kandungan Ca 0,2321%.
Penggunaan Analisis Regresi Linear Berganda untuk Mendapatkan Model Prediksi Respon Asam Lemak Bebas dan Dobi Hasil Rebusan Tandan Buah Segar Sawit
Authors: Imam Pandu , Santosa Santosa , Berd Isril , Kasim Anwar
Published: May 2018

Target of this research are : ( 1) Knowing physical result of steaming of Fresh Fruit Bunch; ( 2) Knowing the chemical of result of steaming of Fresh Fruit Bunch; ( 3) Finding model of prediction respon result of sterilization of Fresh Fruit Bunch ( 4 ) Determining time depth of steaming most precise to condition of raw material ( FFB ) to be sterilization. This research done at PT.Bio Nusantara Teknologi Bengkulu, by using horizontal type sterilizer. Research method the used  experiment which is  direct to be done at factory.  Multiple regression analysis to analyse data obtained, to the investigation of influence of free variable to variable of respon representing indicator efficacy of sterilization operation. Result of research indicate that treatment of variation : heavy classification of bunches,  fruit maturity and time depth steaming to have an effect on to respon result of sterilization perceived. Model of Prediction of met steaming respon as follows : Y1(Evaporation %) = 5,18 - 0,042 X1- 0,012 X2+0,082 X3 ; Y2 ( Fruit lose, g)=1629,96+8,14X1 - 3,22 X2 - 10,22 X3 ; Y3(Throughput apart mesokarp, g / men ) = - 0,748 - 0,297 X1 + 0,111 X2 + 0,336 X3 ; Y4 (percent heavy of mesokarp = 60,12 - 0,044 X1 + 0,018 X2 - 0,103 X3 ; Y5 ( Amount of kernel break = - 1,515 - 0,06 X1+ 0,035 X2 + 0,115 X3 ; Y6 ( FFA )= - 0,655 + 0,011 X1 + 0,029 X2 + 0,032 X3 and  Y7 ( DOBI) = 5,205 - 0,001 X1 + 0,01 X2 - 0,024 X3. Time depth steaming correct to braise small FFB, unrippe = 95 minute with score assess 7; Small FFB, mature = 95 minute with score assess 6; Small FFB over  mature = 90 minute with score assess 6. Time depth steaming correct for big FFB, unrippe = 100 minute with wight assess 6; Big FFB mature = 80 minute with score assess 5 and for big FFB, over mature = 95 minute with score assess 6.
Penghambatan Peningkatan Kadar Asam Lemak Bebas (Free Fatty Acid) pada Buah Kelapa Sawit dengan Menggunakan Asap Cair
Authors: Maimun Teuku , Arahman Nasrul , Hasibuan Fikriatul Arifah , Rahayu Putri
Published: May 2018

Abstract                                                                        One cause of the increase in free fatty acids (FFA) in Crude Palm Oil (CPO) is the activity of lipase-producing microorganisms in the oil palm fruit. Lipase is a biocatalisator which accelerate oil-hydrolysis reaction. High Free Fatty Acid Levels (FFA) will caused rancidity, change the taste and color of the oil. To solve this problem, post-harvest palm fruits should treat with some special treatment, e.g. addition of anti-microbial material, such as liquid smoke The purpose of this study was to determine the effect of liquid smoke on oil palm fruit, the inhibition of elevated levels of free fatty acids (FFA) on CPO. The factors reviewed in this study is the concentration of liquid smoke used; 5, 15, and 25% and the standing time; 12, 16 and 20 hours. The parameters observed in this study are free fatty acids (FFA), water, and impurities. The results showed that the higher the concentration of liquid smoke added, the higher inhibition of oil hydrolysis. CPO levels of FFA decreased at approximately 0,03 to 0,37% after the addition of liquid smoke. Highest inhibition on ALB increase was obtained in the treatment of the sample with the addition of 25% liquid smoke and 12 hours of standing time, which is 2,46%. Keywords: Crude Palm Oil (CPO), Free Fatty Acid (FFA), Water, Impurities, Liquid Smoke.Abstrak       Salah satu penyebab peningkatan asam lemak bebas (ALB) di dalam Crude Palm Oil (CPO) adalah, karena adanya aktivitas mikroorganisme penghasil lipase di dalam buah kelapa sawit. Lipase merupakan biokatalisator yang mempercepat reaksi hidrolisis minyak. Kadar Asam Lemak Bebas (ALB) yang tinggi menyebabkan ketengikan, perubahan rasa dan warna pada minyak. Untuk mengatasi masalah ini, buah kelapa sawit perlu diberi perlakuan khusus, yaitu penambahan bahan anti mikroba pada buah kelapa sawit pasca panen, salah satunya adalah asap cair. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh penambahan asap cair pada buah kelapa sawit, terhadap penghambatan peningkatan kadar asam lemak bebas (ALB) pada CPO. Adapun faktor yang ditinjau dalam penelitian ini adalah konsentrasi asap cair yang digunakan, yaitu 5, 15, dan 25% dan waktu pendiaman, yaitu 12, 16, dan 20 jam. Parameter yang diamati dalam penelitian ini antara lain, asam lemak bebas (ALB), air, dan kotoran. Hasil penelitian menunjukkan bahwa semakin tinggi konsentrasi asap cair yang ditambahkan, maka penghambatan hidrolisis minyak semakin tinggi. Kadar ALB pada CPO yang dihasilkan menurun sekitar 0,62 – 2,55% setelah penambahan asap cair. Penghambatan peningkatan ALB tertinggi diperoleh pada perlakuan sampel dengan penambahan 25% asap cair dan waktu pendiaman 12 jam, yaitu 2.46%. Kata kunci : Crude Palm Oil (CPO), Asam Lemak Bebas (ALB), Air, Kotoran (Impuritis), Asap cair (Liquid Smoke)
Kajian Prospek Agroindustri Fillet Ikan Patin di Kabupaten Mesuji, Provinsi Lampung
Authors: Yuliana Neti , Hidayati Sri , Priyantini Masithoh
Published: May 2018

This study aimed to identify the type of catfish  commodity based-Agroindustry that are potential to be developed in Mesuji Regency and to know the value added potential commodity processing into agro-industry products. The methods used in this research were survey and interview method. Data analysis at the research stage consists of determining the types of processed products using Analytical Hierarchy Process devices and determination of added value using Hayami method. The results showed that catfish was a potential fishery commodity to be developed in Mesuji District with an alternative processing in the form of fillets. Processing of catfish into fillet gives added value of Rp. 12,355 and profit of Rp. 10.242 per kg of raw material.
Assessment of health-related quality of life (HRQoL) in patients with spasmodic dysphonia
Authors: Verma Alok , Gupta Babita , Agarwal Saurabh
Published: May 2018

Background: There is paucity of literature regarding health related quality of life in Spasmodic Dysphonia (SD) especially from India. This study assessed HRQoL in it’s global and disease specific aspect by previously validated instruments in patients with SD.Methods: The study was performed in AIIMS, New Delhi. Subjects with SD as well as age and gender matched healthy controls were enrolled from Movement Disorder and botulinum toxin clinic, Department of Neurology, AIIMS, New Delhi. Uneducated patient, those could not read questionnaires & cases who had received botulinum toxin within 6 months were excluded from the study. Each patient filled SF-36, BDI, VoiSS-30 and VPQ questionnaire.Results: 14 pts of Spasmodic Dysphonia (SD) were enrolled. Compared with controls SD patients suffered from statistically significant impaired global health related quality of life (SF36) in areas of role physical (p = 0.007), general health (p = 0.004), social functioning (p = 0.024), role emotion (p = 0.008) and mental health (p=0.039). Patients with SD scored much worse in BDI scale than their control group (12.57±8.0 vs. 4.71±5.0, p=0.005). 65% pt of SD had depression out of whom 14% had moderate depression. SD patient group showed statistically significant impaired scores in disease-specific QOL (VoISS) in 2 out of 3 subscales, impairment (p= <0.001) and emotional (p=<.001) but not in physical (p=0.44). Voice quality of patients with SD was severely affected compared to controls (mean 37± 8.0 vs. 12.9± 1.5).Conclusions: This study clearly demonstrated that patients with SD suffered from significant impairment in HRQoL as compared to controls. Higher proportion of patients with SD suffered from mild to moderate depression compared to their control.
Knowledge, awareness and practices regarding dengue fever among people attending at UHTC, KBNIMS, Kalaburgi
Authors: Shaheen Shahnaz , Motakpalli Kaviraj , Bendigeri N. D. , Jamadar Deepak
Published: May 2018

Background: Dengue fever (DF) is a rapidly spreading mosquito-borne viral illness all over the world. DF has expanded to new countries and from urban to rural areas. Rapid urbanization, environmental changes and neglected areas result in vector breeding which causes rise in dengue outbreaks. The objective of this study was to assess the knowledge, awareness and practices regarding DF among people residing in urban field practice area of KBNIMS, Kalaburagi.Methods: A cross-sectional study was conducted among general patients attending UHTC, KBNIMS, Kalaburagi using a pre-tested questionnaire. The study population consists of 210 study subjects. Knowledge, awareness and practices of DF among study population was represented as proportions (%).Results: Out of 210 individuals interviewed, 39.04% identified fever as a cardinal symptom of DF. The knowledge about other symptoms of DF was low among participants. 71.90% knew that DF is transmitted by mosquito bite. The correct timing of biting time was known by only 13.81%. In the present study only one third of the participants had received information about DF from health professionals. Despite low knowledge, the participants had good attitude and most of them reported good preventive practices against dengue prevention and control.Conclusions: The knowledge of participants of our study was low and the practice was good for protection from other mosquito borne diseases. Therefore massive awareness campaigns are urgently required to protect the health of people against DF and to limit future spread of DF in this part of our country.
Inter relationship of plasma lipid profile parameters with plasma uric acid levels in psoriasis
Authors: S. Srinivas , Goudappala Prashanthkumar , R. T. Kashinath
Published: May 2018

Background: Psoriasis is a chronic immune mediated skin disease accompanied with disturbances in systemic lipid turnover. Hyperuricemia has been frequently observed as an additional complication in psoriasis. The relationship between the raised plasma lipid parameters and the uric acid levels in psoriasis need to be ascertained. A study was undertaken to assess the possible relationship of plasma lipid parameters with plasma uric acid levels in psoriasis and to relate any such relationship to psoriasis disease severity.

Methods: Non arthritic psoriasis patients were randomly selected and were grouped into mild (Group 1), moderate (Group 2) as well as severe (Group 3) based on their PASI scores. Plasma lipid parameters and uric acid levels were assessed in these patients.

Results: The results show a significant (p<0.001) parallel raise in plasma uric acid levels along with plasma lipid parameters with the severity of disease in these patients.

Conclusions: A plasma uric acid level along with plasma total cholesterol and triacylglycerol levels fetch much information on the severity of psoriasis disease.

 
Nutritional dermatoses and its association with anemia and systemic illness
Authors: Lakhani Som J. , Surti Nishit K. , Doshi Mrugal V. , Panchasera Sanket R. , Vasvani Vivek N. , Bapna Mani R. , Raval Ranjan C. , Billimoria Freny E. , Lakhani Jitendra D.
Published: May 2018

Background: Mucocutaneous changes may be a “tell-tale” signs of multi nutrional deficiency including anemia. Some are very characteristic of a specific nutrient deficiency, while other signs may overlap and will reflect multiple deficiency states.

Methods: To scrutinize clinical signs of multi nutritional deficiencies accompanied with anemia, this observational clinical study of 75 patients (adult and adolescents) was undertaken. Patients were selected from out-patient and in-patient department (OPD and IPD) of dermatology as well as General Medicine ward including medical ICU. Relevant investigations were carried out whenever required. Detail clinical history of diet, tuberculosis as well as HIV disease, worm infestation, other co-morbid conditions and alcohol intake were taken. Clinical signs of nutritional deficiencies like of Pellagra, Kwashiorkor, Beriberi, Ariboflavinosis and other signs of avitaminosis and micronutrient deficiency were looked for in all such patients.

Results: Of 75 patients, 37 were male (M) and 38 female (F). One of the important findings was that one third patients were admitted in ICU and in 60 of 75 patients risk factors could be identified. Mental illness, ICU admission, elderly age, systemic illness and alcohol consumption were the predisposing factors. Iron deficiency anemia was the commonest anemia followed by dimorphic anemia with other multinutrional manifestations. Clinical signs which were observed due to multinutritional deficiency were of pellagra dermatosis, kwashiorkor, koilonychia with pale tongue and mucous membranes, angular cheilosis, hair changes of various types and other signs due to systemic involvement.

Conclusions: Anemia may be associated with other nutritional abnormality which is reflected in changes in the skin, mucous membrane, hairs and nails. Nutritional dermatosis and anemia can be part of systemic illness which maybe reflected as deficiency of multiple nutritive factors.
Redução do Desmatamento na Amazônia: o papel dos mecanismos institucionais
Authors: Rodrigues Marcos , Silva David Costa Correia , Azevedo Junior Wladimir Colman
Published: May 2018

O objetivo deste artigo foi avaliar a mudança institucional sobre o desmatamento na Amazônia nas últimas duas décadas. Através do levantamento estatístico do desmatamento e das multas ambientais na região, foi possível correlacionar a evolução do ambiente institucional formal com a atuação do Estado no cumprimento das leis (enforcement), mais especificamente os casos dos estados de Mato Grosso e Pará. Os resultados demonstram que, embora a legislação e atuação do Estado tenham contribuído para a redução do desmatamento, a economia regional continua a se basear em atividades primárias extensivas (agricultura, pecuária e extrativismo vegetal e mineral) e que atividades ilegais continuam a existir, demonstrando os limites da capacidade do ambiente institucional em conter o desmatamento. Desenvolver novos mecanismos que integrem outros atores sociais é necessário para a preservação da Amazônia.
Tarihi Yapı Malzeme Özelliklerinin Dinamik Parametrelerle Belirlenmesi: Lala Paşa Camii Örneği
Authors: KOCAMAN İrfan , OKUYUCU Dilek , KAZAZ İlker
Published: May 2018

Sismik olarak dünyanın en aktif
bölgelerinden birisi olan Anadolu yarımadası pek çok medeniyetin izlerini
taşıyan tarihi yığma yapılara ev sahipliği yapmaktadır. Mimari kültür
mirasımızın depremlerin yıkıcı etkilerinden korunabilmesi için bu yapıların
dinamik davranışlarının gerçekçi yaklaşımlarla belirlenmelidir. Yığma yapılarda
malzeme mekanik özelliklerinin tespitindeki zorluk ve belirsizlikler bilgisayar
ortamında kurgulanan yapısal modelleri her zaman sorgulanır kılmaktadır. Bu
çalışmada Erzurum il merkezinde yer alan Lala Mustafa Paşa Camii’nin taşıyıcı
eleman ve malzeme özelliklerini belirlemek için literatürde mevcut yığma
malzeme modelleri incelenerek teorik bir yaklaşım ortaya konulmuştur. Yapının
sonlu eleman modeli oluşturularak teorik modal analizi, Operasyonal Modal
Analiz yöntemiyle de deneysel modal analizi gerçekleştirilmiştir. Teorik ve
deneysel olarak belirlenen modal parametreler irdelenerek yapının gerçeğe en
yakın malzeme özellikleri belirlenmiştir. Elde edilen sonlu eleman modelinde, 1992
Erzincan Depremi ivme kayıtları kullanılarak gerçekleştirilen dinamik analizler
neticesinde yapının göçme mekanizması araştırılmıştır.
Management of difficult intubation in the case with substernal goiter underwent cardiac surgery
Authors: Lafçı Ayşe , Gökçınar Derya , Camgöz Süleyman , Günaydın Serdar
Published: May 2018

Redo thyroid
surgery is difficult for several reasons and may be complicated. In some cases
airway management can be more difficult unexpectedly. In this situation, special
airway devices may be required. Here we present a case of a 67-year-old female
patient who suffer from recurrent substernal goiter and has dyspnea, cough, and
fatigue. In this case, difficult intubation was managed with a gum elastic
bougie that was placed into the classical laryngeal mask airway. Laryngeal mask
airway was removed while gum elastic bougie was left in place to guide
endotracheal tube insertion. The endotracheal tube was slipped over gum elastic
bougie. In cases of difficult intubation, endotracheal intubation can be
achieved with the guidance of  gum
elastic bougie placed through the laryngeal mask airway.
Prevention of lung injury by iloprost following hind limb ischemia and reperfuison model in rats
Authors: Tekeli Kunt Atike , İsbir Selim , Civelek Ali , Akgun Serdar , Ergen Arzu , Yapicier Ozlem , Sav Aydin , Arsan Sinan
Published: May 2018

Aim: The major part of tissue damage
occurs upon reperfusion and is mediated by activated neutrophils that release
oxygen free radicals. Following hind-limb ischemia/reperfusion, lung injury due
to neutrophil infiltration and oxygen free radicals has been demonstrated.
Previous studies have shown that this injury can be prevented
pharmacologically. Iloprost is a long acting stable analog of prostacyclin. The
aim of this study is to test the effect of iloprost in prevention of lung
injury due to lower limb ischemia/reperfusion. Material and Methods: Through a midline
laparotomy infrarenal abdominal aorta was approached and cross-clamped in 20
male Spraque-Dawley rats for 2 hours. At the time of declamping Group I animals
(n=8) received iloprost (0,1µg/kg/min) and Group II animals (n=8) received
normal saline (0,1ml/kg/min) continously for 4 hours. Third group was the sham
group (n=4). The lung tissue assays were performed for measurement of lipid
peroxidation end product malondealdehyde and also total glutathione. Lung
tissues were also examined histopathologically under light microscopy. Results: The malondealdehyde levels in
the iloprost group were significantly lower than the control group (p<0,05).
The glutathione levels did not show any difference between the iloprost and the
control groups (p>0,05). Histopathological examination revealed that the
structure of the lung tissue was preserved in the iloprost group whereas lung
tissue of the control group had evidence of injury.

Conclusion: Our results suggest that
iloprost reduces the production of oxygen free radicals and prevents lung
injury due to lower limb ischemia reperfusion.
Research on the Relationship between Human Resource Management Practices and Employee Retention in Chinese Overseas Enterprise Evidence from Huawei in Senegal
Authors: B. Abdoulaye
Published: May 2018

The core objective of this study was to investigate on the impact of selected human resource management practices, namely recruitment, and selection, training and development, performance evaluation, remuneration and promotion on employee retention through organizational commitment, trust and inclusion at Huawei in Senegal. For that purpose, data were collected by verified structured questionnaire. The different theories have shown that HRM practices have a positive and significant relationship with employee retention. Besides, there was evidence that found that organizational commitment could act as a mediator between these HRM practices and employee retention. Similarly, different theories and literature have backed up the fact that organizational trust and inclusion will affect positively and enhance employee commitment towards the organization. Data were collected to identify all types of relationships among different constructs. As a result, a well-structured questionnaire was developed on the basis valid and tested reliable instruments from different academic journals in the field of management. The hypotheses that were constructed on the basis of a model that was tested through collected data. This study is purely quantitative, and the source of data was both primary and secondary. Thus, about 400 questionnaires were distributed to different Huawei Company sections in Senegal, but only 318 were considered appropriate for final analysis. To get the expected results and finding, SPSS 20, Excel and AMOS 21 were the main statistical software used to analyze data. Confirmatory factor analysis (CFA) was also performed to check reliability and validity, average variance extracted from the measurement model. Multilinear regression analysis has been used to test the proposed relationships between the independent and dependent variables. Then, Analysis of Variance (ANOVA) has been used according to the perspective objectives of the current study. Pearson correlation analysis was performed to examine the correlation between different variables. Besides, the structural equation modeling (SEM) analysis was also used to find out the simultaneous and continuous relationship between the different variables, while linear regression modeling was applied to test the research hypotheses. The findings of the study revealed that selected human resource management (HRM) practices have a positive and significant relationship with employee retention.
Leadership Styles and Job Performance: a Literature Review
Authors: Al-Malki Mohammed , Juan Wang
Published: May 2018

The present research is a literature review of the leadership styles and its effectiveness within the organization team-building. Specifically, this paper tries to review the literature in the sphere of job performance focusing on the leadership styles. Both leadership types and styles had been reviewed in relation to the productivity in the organization along with the role stressors and role ambiguity. Leaders are claimed to have a positive impact on the efficiency of the organization by influencing the team members’ job performance. Additionally, literature review explores the concepts of role stressors such as role ambiguity and role conflict, which are often found as the most important source of job dissatisfaction and poor job performance. Understanding the nature of role stressors and potential sources which may cause them to will help organizations to take control of managing role stressors. Also, it was found that the relationship between job performance and job cooperation was somewhat controversial in the literature. Therefore, it is important to understand the nature of different leadership styles and assess their impact on resolving different organizational problems.