bluuebunny/crossref_metadata_2025 huggingface dataset:
BCAR3 promotes head and neck cancer growth and is associated with poor prognosis
Authors: Zhang Ze , Wang Yafei , Wang Yun , Wang Chunli , Shuai Yanjie , Luo Jingtao , Liu Ruoyan
Published: October 2021

Breast cancer anti-estrogen resistance protein 3 (BCAR3) is involved in anti-estrogen resistance and other important aspects of breast cancer. However, the role of BCAR3 in other solid tumors remains unclear. The relationship between the clinicopathologic characteristics of head and neck squamous cell carcinoma (HNSCC) patients and BCAR3 was analyzed using the Wilcoxon’s signed-rank test and logistic regression. The association between BCAR3 expression and clinicopathologic features and survival was analyzed using Cox regression and the Kaplan–Meier method. In vivo and in vitro assays were performed to validate the effect of BCAR3 on HNSCC growth. BCAR3-related mRNAs were determined by calculating the Pearson’s correlation coefficient based on The Cancer Genome Atlas (TCGA). Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses, and gene set enrichment analysis (GSEA) were used to predict the potential functions of BCAR3. BCAR3 expression is overexpressed in HNSCC and was shown to be associated with perineural invasion (PNI) and poor survival. BCAR3 silencing significantly attenuated the proliferation of HNSCC cells, whereas BCAR3 depletion inhibited tumor growth in vitro. GO and KEGG functional enrichment analyses, and GSEA showed that BCAR3 expression in HNSCC was associated with biological processes, such as cell adhesion, actin binding, cadherin binding, and angiogenesis. BCAR3, which promotes HNSCC growth, is associated with perineural invasion and may be a potential molecular prognostic marker of poor survival in HNSCC.
Dataset of concurrent EEG, ECG, and behavior with multiple doses of transcranial electrical stimulation
Authors: Gebodh Nigel , Esmaeilpour Zeinab , Datta Abhishek , Bikson Marom
Published: October 2021

We present a dataset combining human-participant high-density electroencephalography (EEG) with physiological and continuous behavioral metrics during transcranial electrical stimulation (tES). Data include within participant application of nine High-Definition tES (HD-tES) types, targeting three cortical regions (frontal, motor, parietal) with three stimulation waveforms (DC, 5 Hz, 30 Hz); more than 783 total stimulation trials over 62 sessions with EEG, physiological (ECG, EOG), and continuous behavioral vigilance/alertness metrics. Experiment 1 and 2 consisted of participants performing a continuous vigilance/alertness task over three 70-minute and two 70.5-minute sessions, respectively. Demographic data were collected, as well as self-reported wellness questionnaires before and after each session. Participants received all 9 stimulation types in Experiment 1, with each session including three stimulation types, with 4 trials per type. Participants received two stimulation types in Experiment 2, with 20 trials of a given stimulation type per session. Within-participant reliability was tested by repeating select sessions. This unique dataset supports a range of hypothesis testing including interactions of tDCS/tACS location and frequency, brain-state, physiology, fatigue, and cognitive performance.
Quantitative analysis of biochemical processes in living cells at a single-molecule level: a case of olaparib–PARP1 (DNA repair protein) interactions
Authors: Karpińska Aneta , Pilz Marta , Buczkowska Joanna , Żuk Paweł J. , Kucharska Karolina , Magiera Gaweł , Kwapiszewska Karina , Hołyst Robert
Published: October 2021

Fluorescence correlation spectroscopy was applied to quantify drug-target interactions directly in living human cells.
Collagen-based biocomposites inspired by bone hierarchical structures for advanced bone regeneration: ongoing research and perspectives
Authors: Qin Di , Wang Na , You Xin-Guo , Zhang An-Di , Chen Xi-Guang , Liu Ya
Published: October 2021

Collagen-based biocomposites inspired by bone hierarchical structure were prepared into different forms by combining with various materials, which serve as delivery systems to enhance bone regeneration.
Dye–polyoxometalate coordination polymer as a photo-driven electron pump for photocatalytic radical coupling reactions
Authors: Ming Zheng , Zhang Tiexin , Tian Wenming , Li Jianing , Liu Zhenhui , Liu Renhai , Liu Zhongmin , Duan Chunying
Published: October 2021

Coordination polymer containing triphenylamine and polyoxometalate photoinduced long-lived charge-separation pairs, which unidirectionally pumped multiple electrons from external electron donors to acceptors, furnishing value-added radical couplings.
Exploring hitherto uninvestigated reactions of the fatty acid peroxygenase CYP152A1: catalase reaction and Compound I formation
Authors: Onoda Hiroki , Tanaka Shota , Watanabe Yoshihito , Shoji Osami
Published: October 2021

We have found that CYP152A1 possesses catalase activity, which competes with the hydroxylation of long-chain fatty acids, the oxidation of non-native substrates, and haem degradation.
Bifunctionalization of unsaturated bonds via carboxylative cyclization with CO2: a sustainable access to heterocyclic compounds
Authors: Cai Shuai-Fang , Li Hong-Ru , He Liang-Nian
Published: October 2021

This review provides the state of the art of bifunctionalization of unsaturated bonds in carboxylative cyclization with CO2 and sheds light on its future development.
Co-dissolution of cellulose and silk fibroin in levulinic acid-derived protic ionic liquids for composited membrane and fiber preparation
Authors: Yue Wang , Zhang Lihua , Deng Lulu , Guo Yuanlong , Xu Qinqin , Peng Wei , Chen Peng , Xie Haibo , Zou Guanglong , Liang Songmiao
Published: October 2021

Biobased PILs were identified to have good solubility to cellulose and silk fibroin, providing a sustainable dissolution processing platform for the preparation of cellulose/silk fibroin composited membranes and fibers.
Expression and function of SLC38A5, an amino acid-coupled Na+/H+ exchanger, in triple-negative breast cancer and its relevance to macropinocytosis
Authors: Ramachandran Sabarish , R. Sennoune Souad , Sharma Monica , Thangaraju Muthusamy , V. Suresh Varshini , Sneigowski Tyler , D. Bhutia Yangzom , Pruitt Kevin , Ganapathy Vadivel
Published: October 2021

Metabolic reprogramming in cancer necessitates increased amino acid uptake, which is accomplished by up-regulation of specific amino acid transporters. However, not all tumors rely on any single amino acid transporter for this purpose. Here, we report on the differential up-regulation of the amino acid transporter SLC38A5 in triple-negative breast cancer (TNBC). The up-regulation is evident in TNBC tumors, conventional and patient-derived xenograft TNBC cell lines, and a mouse model of spontaneous TNBC mammary tumor. The up-regulation is confirmed by functional assays. SLC38A5 is an amino acid-dependent Na+/H+ exchanger which transports Na+ and amino acids into cells coupled with H+ efflux. Since cell-surface Na+/H+ exchanger is an established inducer of macropinocytosis, an endocytic process for cellular uptake of bulk fluid and its components, we examined the impact of SLC38A5 on macropinocytosis in TNBC cells. We found that the transport function of SLC38A5 is coupled to the induction of macropinocytosis. Surprisingly, the transport function of SLC38A5 is inhibited by amilorides, the well-known inhibitors of Na+/H+ exchanger. Down-regulation of SLC38A5 in TNBC cells attenuates serine-induced macropinocytosis and reduces cell proliferation significantly as assessed by multiple methods, but does not induce cell death. The Cancer Genome Atlas database corroborates SLC38A5 up-regulation in TNBC. This represents the first report on the selective expression of SLC38A5 in TNBC and its role as an inducer of macropinocytosis, thus revealing a novel, hitherto unsuspected, function for an amino acid transporter that goes beyond amino acid delivery but is still relevant to cancer cell nutrition and proliferation.
Identifying the Core Vocabulary for Adults With Complex Communication Needs From the British National Corpus by Analyzing Grouped Frequency Distributions
Authors: Shin Sangeun , Park HyunJu , Hill Katya
Published: October 2021

Purpose

This study is aimed to identify the high-frequency vocabulary (HFV), otherwise termed “core vocabulary” for adults with complex communication needs.

Method

Three major characteristics of the HFV—a relatively small number of different words (NDW), a relatively high word frequency, and a high word commonality across speakers—were examined so as not to lose any candidate words for the HFV. Specifically, instead of applying the traditionally used cutoff word frequency of 0.5‰, a grouped frequency distribution was used to examine the appropriate frequency ranges to determine the HFV candidates. To improve the representativeness of the HFV across ages, social backgrounds, conversation situations, and topics, 330,000 spoken words of 66 adults (29 men and 37 women;
M
age
= 45.47 years,
SD
= 16.07) were extracted from the British National Corpus database for analysis.

Results

A distinct pattern of NDW was observed from the frequency of 0.1‰ in the grouped frequency distribution. In total, 671 words were found to be candidates for the HFV, accounting for 90.94% of the total sample words. After the word commonality analysis indicated at least 80% commonality across speakers, 203 words were selected for the final HFV; accountability was calculated at 80.62%.

Conclusions

With the innovative word analysis approach, this study provided an HFV list that can be used for a wide range of conversation topics. This method provides a scientific and principled approach to identifying and organizing vocabulary for augmentative and alternative communication (AAC) intervention that does not exist in many AAC resources that promote “core vocabulary” with identifying the source for vocabulary selection.
Effect of the type and method of additives on the productivity of mushrooms grown in industrial conditions
Authors: Alexandrova Ekaterina G. , Lazareva Tatyana G.
Published: October 2021

The paper summarizes and analyzes the results of practical studies on the cultivation of Agaricus bisporus champignon mushrooms on a synthetic substrate with the introduction of organic additives into it – food and processing wastes: brewing waste, soybean and sunflower meal semolina. A yield analysis was carried out; indicators characterizing the quality of Agaricus bisporus mushrooms were studied; dependence of yield and quality of mushrooms on flush was demonstrated. It was noted that the preparation time of the substrate affects the number of flushes, respectively, and, correspondingly, on the yield of mushrooms: when growing mushrooms on a synthetic substrate prepared in the spring-summer period, two flushes are noted and, as a result, a higher yield is noted compared to mushrooms grown on a substrate prepared in the autumn-winter period. The study of the quality of fruit bodies showed that the use of additives increased the content of protein, fiber, fat and ash elements (potassium, phosphorus, calcium, sodium and magnesium). The results showed that the brewing waste is the best organic additive, which contributes not only to the growth of yield, but also to the improvement of the quality of cultured mushrooms. The study demonstrated that the quality of mushrooms obtained in the first flush exceeds the qualitative indicators of mushrooms grown in the second flush. The authors concluded that it is advisable to use organic waste (brewing waste, sunflower meal) as a substrate element when growing mushrooms in industrial conditions.
Extraction and study of Intracellular compounds of sedimentary wine yeast - waste product of wine production
Authors: Chernousova Inna , Zaitsev George
Published: October 2021

The present work describes the results of research of a complex of substances obtained from sedimentary wine yeast by extraction with food extractants with the use of ultrasound. The filtrates of alcoholic extracts of yeast and sediments isolated from filtrate were investigated. It has been shown that hydrophobic substances moderately soluble and poorly soluble in alcohol, such as ethyl esters of fatty acids, fatty acids, phospholipids, sterols, squalene, were isolated from sedimentary wine yeast by extraction with alcohol-containing extractants. The mechanical effect of ultrasound provides faster and more complete penetration of the solvent into the intracellular substances. Ultrasound allows one to achieve greater penetration of the solvent into plant tissues and improve mass exchange. Ultrasonic waves, causing cavitation in the liquid, destroy cell walls and promote the release of cell matrix components. Thus, during the US treatment of suspended sedimentary wine yeast a mixture of fatty acid ethyl ester more than 2 times and squalene - 1.5 times, compared to the control, is observed.
Modernization of reclamation agriculture management systems
Authors: Yurchenko Irina , Bandurin Mikhail , Bandurina Inna
Published: October 2021

Today, a brand new strategy that can foster agricultural production is being shaped based on IT solutions. The paper characterizes the state and prospects for the development of digital farm management, the challenges of mastering digital innovations by agricultural enterprises and ways to tackle them at the present stage. A study is relevant due to the lack of a conceptual approach to the evolution of information digital systems in the sector of ameliorative economy in the context of growing requirements for environmental safety and competitiveness of agricultural production. The solutions to create a common information environment uniting an enterprise with suppliers of resources and consumers of products (services) are also increasingly relevant today. A methodological toolkit rests on some general scientific approaches, including analysis and synthesis, methods of deduction and systems analysis, cluster approach. After careful evaluation of automated processes at reclamation enterprises, there can be no doubt that it is necessary to improve the efficiency of information and technological support for management decisions by digital systems. The challenges are related to: lack of proper concept and methodology of modern digital systems, as well as procedures for the integration cooperation of information resources and a digital management system operations for managing them; unified algorithms for handling information; automation operations that meet the present management requirements; qualified experts encouraged to improve the use of digital technologies. The basic procedures for enhancing digital systems at enterprises include: analytical evaluation of current production situation, development of a functional design and model of the integrated digital system; creation of a mechanism for its implementation. In the process of transforming digital support for managerial actions, the following actions are possible: modification of the structure of existing processes; automation of conventional technological and organizational production procedures; alignment of existing processes subject to the technologies being integrated; identification of new opportunities for operations.
Development of resource-saving technologies for rice cultivation on rice irrigation systems in the Krasnodar Territory
Authors: Prikhodko Igor , Vladimirov Stanislav , Alexandrov Daniil
Published: October 2021

According to the studies carried out by the US Geological Survey (USGS) under the project GFSAD30, Russia ranks fourth in the world in the number of fertile lands. However, today there are some problems that “slow down” the development of the Russia’s agricultural sector, including the rice-planting complex. One of the main problems of the Russian agro-industrial complex is unsustainable environmental management, which leads to inefficiency and sometimes loss of agricultural production. This is caused by the “rigidity” of the legal framework, the reluctance or inability of the economy to switch to new resourcesaving technologies, as well as the fear of partially or completely losing the crop when switching to new technologies. For the “soft” transition of the economy to new resource-saving technologies, we propose a resource-saving technology for cultivating rice on underground drip irrigation under mulch film on rice irrigation systems, the introduction of which proved its effectiveness, as well as the relevance of our study. The efficiency of proposed resource-saving technology of rice cultivation on drip irrigation is expressed in the increase of profitability of rice production by 26%, reduction of irrigation norm by more than 5 times, labor intensity of rice production by 42% and material costs by 24%. The proposed technology not only reduced the anthropogenic load, but also improved the land reclamation condition, including the situation in the rice irrigation ecosystem. Further development of drip technologies in the rice sector of Russia will allow developing fundamentally new, ecological-reclamative, balanced rice crop rotation with the inclusion of vegetable and cucurbits crops. The proposed technology will provide an opportunity to cultivate rice outside rice irrigation systems on previously rich lands, which will give agro-industrial workers new opportunities and prospects in rice production.
A systemic approach to the research of personnel in agriculture of the region
Authors: Chulkova Elena A. , Rakhmatullina Lyaysana I.
Published: October 2021

Development of an innovative economy gives rise to the need to form a highly competent workforce capable of creating and implementing innovations in a short time. This also applies to agriculture as a sector of the economy that ensures the food security of the regions and the country as a whole. The level and quality of the labor force is considered as the most important resource in the activities and development of the agro-industrial complex. A methodical approach to a systematic study of the use of staffing in agriculture in the region is proposed, the difference of which is the use of econometric modeling to assess the impact on the target indicator of the components of staff by areas of activity and level of qualifications. The application of the approach is shown on the example of the sector of agricultural organizations of municipal districts of the Orenburg region.
Rationale for vehicle parameters for the transportation of straw and hay
Authors: Babkov Andrey , Varavin Vladimir
Published: October 2021

Vehicles for the transportation of straw and hay in loose and pressed forms are considered. A scheme of a transport vehicle for the transportation of straw and hay, a haystack truck, is proposed. The haystack truck consists of a frame, wheels, a trailer device, a finger platform, a mechanism for loweringlifting the front part of the platform, sides, a mechanism for lowering-lifting the rear part of the platform. The results of studies to determine the physical and mechanical properties of straw and hay, necessary to rationale the parameters of the haystack platform, are presented. The dependence of the coefficient of friction of oat straw, barley, winter wheat, millet, buckwheat and alfalfa hay and awnless brome on the fingers of the haystack and loading and unloading surfaces: soil, sod, asphalt, straw, crushed stone on the load and speed is presented. The dependence of the resistance to the introduction of the finger tip of the haystack platform into the straw on the density of the material and the dependence of the load resistance of the vehicle on the angle of inclination of the platform are shown. The results of determining the angles of inclination of the haystack platform during loading, transportation and unloading of straw and hay stacks are presented. Recommendations on the use of a self-loading haystack truck for transporting straw and hay in loose and pressed form are given.
Compositional analysis of fatty acids in cow’s milk when feeding a complex additive based on activated diatomite
Authors: Akhmetova Venera , Dezhatkina Svetlana , Muhitov Asgat , Sharonina Natalya
Published: October 2021

The article presents the research results of the effect of activated diatomite as part of a complex supplement on the composition and ratio of saturated and unsaturated fatty acids in cow's milk. The experiments were carried out in a dairy farm on black-and-white cows. The additive includes a carrieractivated diatomite; fillers are DAPS-organic selenium, sunflower oil and feed yeast and diatomite crumbs. The supplement was included in the diet of cows at the rate of 2% of the dry matter of the diet once a day. The control group did not receive the supplement. The positive effect of the use of the additive on the composition of fatty acids in cow's milk was established. There was an increase in the fraction of saturated fatty acids, which indicates an increase in volatile fatty acids: acetate and 3-hydroxybutyrate. The use of a complex supplement based on activated diatomite contributed to an increase in concentration of capric, lauric, myristic, palmitic and margarine fatty acids. The use of additives for dairy cows helps to increase their productivity, improve the quality of milk composition due to the intensive conversion of feed nutrients.
Growth and development of bulls of different types of productivity
Authors: Donetskikh Alexandr , Grikshas Styapas , Pastukh Olga , Korenevskaya Polina , Kertiev Ruslan
Published: October 2021

The article provides data on the weight growth of bulls of different types of productivity. The growth and development of Black-and-white, Simmental and Aberdeen-Angus bulls were studied during the period of their rearing and feeding. The change in live weight was established, the dynamics and growth rate of the studied bulls were calculated depending on the breed and type of productivity. The research results showed that the Aberdeen-Angus bulls had the highest live weight during fattening - 485.2 kg, which was significantly higher than that of the Black-and-White and Simmental breeds by 68.7 kg (p <0.001) or 14.0% and 19.7 kg (p <0.01), or 4.1% respectively. The average daily gain in live weight from birth to 15 months of age in bulls of Black-and-white, Simmental and Aberdeen Angus breeds amounted to 860.0; 965.1 and 1022.7 grams respectively. In the Aberdeen-Angus cattle, in comparison with the Black-and- White and Simmental breeds, the value of this indicator was significantly higher, by 162.7 g, or 15.9% (p <0.001) and 57,6 g, or 5.6% (p <0.01) respectively. It was found that the type of productivity had a certain effect on the dynamics of live weight, the intensity of growth and development of animals.
Metabolic status of rabbits under physiological adaptation to cage husbandry technology
Authors: Khokhlova Natalia , Semenyutin Vladimir , Eremenko Viktor
Published: October 2021

The article considers changes in biochemical blood parameters depending on the degree of adaptation process manifesting on the plantar surface of hind limbs of different sex rabbits and physiological state under cage husbandry technology. Groups of stud bucks (1st series), pregnant and lactating does (2nd and 3rd series of experiments) were formed according to the stages of structural changes depending on the stress of physiological regulatory processes of adaptation (the systematics proposed by R.M. Baevsky). The authors studied the following factors in serum: total protein, protein fractions (albumin, α-, β-, γ-globulin), creatinine, total bilirubin, urea, uric acid, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase, glucose triacylglycerol and cholesterol. At the stressed stage of regulatory systems the group of bucks showed a reduction of total bilirubin on the background of decrease of ALT, AST and alkaline phosphatase, which can testify to activation of liver function at this stage, and increase in bilirubin, ALT, AST with a simultaneous decrease in alkaline phosphatase, noted at the overstress stage of physiological adaptation regulatory processes, can testify to decrease in the functional activity of hepatocytes.Pregnant rabbits have the most pronounced compensatory reactions in the third stage of the adaptation process: the increase in absolute and relative γ-globulin values indicates the activation of immune factors. An increase in creatinine and urea levels during the gestation period, against a background of developing adaptive changes on the plantar surface of the feet, indicates a decrease in the filtration capacity of the renal tubules.Lactating animals experience an increased physiological load on the liver, which is expressed by an increase in triacylglycerols throughout the adaptation.
State and prospects for development of livestock products in Russia
Authors: Gainutdinov Ilgizar , Mukhametgaliev Farit , Asadullin Nail , Avkhadiev Fayaz
Published: October 2021

The analysis of the state and level of livestock products development substantiates the need for the development of the beef cattle breeding industry. To improve the efficiency of the industry it is advised to benefit more fully from the available natural lands: pastures and hayfields. Attention is focused on the fact that the efficiency and competitiveness in the market for livestock products are significantly influenced by natural and climatic factors that determine the need for other resources. The statistical method confirmed that the number of farm animals in the Russian Federation compared with the pre-reform period has sharply decreased: cattle – by 3 times, cows – by 2.6 times, pigs – by 1.5 times, sheep and goats – by 2.6 times, which has led to a decrease in livestock density in general and in the productivity of agricultural land. The aim of the research was to consider natural resources in the regions of Russia to increase the livestock of farm animals and increase the volume of dairy and beef cattle breeding, especially beef. The scientific novelty lies in the development of recommendations for the further development of animal breeding in Russia based on the principle of historicism and taking into account the tendencies of the world economy in the market of livestock products.
The effectiveness of using zeolite in the processing of spring wheat seeds
Authors: Garafutdinova Kamila , Rakhmanova Gulnara , Prishchipenko Elena , Gaffarova Lilia
Published: October 2021

The article presents the results of vegetation studies on dusting the seeds of agricultural crops with zeolite. The experiment used seeds of spring wheat variety Ulyanovskaya-105 and mechanically activated zeolite of the Tatar-Shatrashansk deposit of the Republic of Tatarstan. The activated zeolite was obtained by mechanical activation using a crushing and screening plant at OAO Zeolites of the Volga Region, the particle size is 0.20 mm. The effect of dusting seeds with zeolite in various doses (25 kg/t, 50 kg/t, 75 kg/t, and 100 kg/t) on the growth and development of spring wheat plants, as well as on the quality indicators of grain, has been evaluated. The results revealed a positive effect of agro mineral on such parameters as seed germination (increase by 2.0–12.0%), chlorophyll content in plants in the tillering phase (by 7.4–33.3%), as well as on morphometric and biochemical parameters - plant height (by 2.5% -10.1%), the number of grains in the ear (by 7.7%), plant biomass (by 1.7% -7.9%) and the protein content in the grain (by 0.6-4.2%).
Obtaining “ghosts” of red blood cells with a set ion concentration as models for studying Na+, K+ - ATPase
Authors: Mosyagin Vladimir , Ryzhkova Galina , Belyaev Alexey , Sidorenko Semyon
Published: October 2021

The article considers the production of red blood cell “ghosts” and their application as a model for studying Na+, K+ - ATPase. Various variants of liposomes are used as test objects for studying ion transport, but the best model of biological membranes for studying ion transport and ATPase pumps are the «ghosts» of red blood cells. The activity of blood Na+/K+ - ATPase is determined mainly in the suspension of red blood cell “ghosts”. This is due to the need to remove the interfering compound – hemoglobin - and obtain “ghosts” that are necessary for accurate measurement of the activity of the enzyme. In this scientific work, studies were conducted to determine the concentrations of Na+ and K+ ions in the blood and red blood cells of cows and calves of various ages by atomic absorption and atomic emission spectroscopy. The values of these concentrations of Na+ and K+ ions were used to obtain red blood cell “ghosts”. “Ghosts” of red blood cells with a set concentration of sodium and potassium ions were obtained by the method of J. T. Dodge, in the modification of Zhumadilov Zh. Sh. and Gening T. P. and in our modification. Studies of the concentration of Na+ and K+ ions in the obtained «ghosts» of red blood cells showed their full compliance with the calculated values.
Effect of applications of collagen ointments on the healing of purulent-necrotic ulcers of finger tissues in cows
Authors: Andenko Victor , Tolkachev Vladimir , Kolomiytsev Sergey
Published: October 2021

The purpose of the research was to obtain new experimental samples of collagen antiseptic ointments and to evaluate the effect of their use on the healing of purulent-necrotic ulcers of the finger tissues in cows. To achieve this goal, two experimental samples of collagen ointment were made: the first sample was a collagen analog of «Levomekol» ointment, and the second sample was a collagen ointment based on «Kemistep+» hoof sanitizer. The evaluation of the effect of their application on the healing of purulent-necrotic ulcers of the finger tissues was carried out in two experimental groups of sick animals with purulent-necrotic ulcers of the hoof crumb tissues of 7 heads each. In the first experimental group of animals, the first experimental sample of the ointment was applied, in the second - the second experimental sample. According to the results of scientific studies, it was found that the use of collagen ointment with the disinfectant «Kemistep+» on purulent-necrotic ulcers of crumb contributed to a decrease in their number. The epithelization index in the second experimental group compared to the first experimental group indicated a more positive effect of the use of collagen ointment with the disinfectant «Kemistep+» on the healing of purulent-necrotic ulcers of the finger tissues in cows than similar applications of the collagen analogue of the ointment «Levomekol».
The objective need and trend of ensuring the food security in Russia in conditions of import substitution
Authors: Mukhametzyanov Rafail , Romanyuk Maria , Ostapchuk Tatiana , Ivantsova Natalya
Published: October 2021

The article describes in detail two key elements of Russian food security: self-sufficiency and the potential of the domestic food market. It is these two factors that are regulated at the state level through the standards included in their composition. The article shows how the state policy of the Russian Federation for the regulation of food markets changed from the reform period to the present. Our studies have shown that the strengthening of measures for import substitution after 2014 has not yet allowed us to achieve complete self-sufficiency in all types of food. This is partly due to objective restrictions (for vegetables and fruits) and insufficient efforts to develop the industry (dairy and meat cattle breeding). In addition, by those types of food, according to which the thresholds of self-sufficiency are made, the dependence on imports is shifted to the area of industries that provide means of production (seeds, technique, etc.). A detailed analysis of food imports showed that after 2014 its volume decreased (as a result of a reduction in the effective demand and growth in agricultural production), while its commodity structure has practically changed. Analysis of the capacity and structure of the food market of the Russian Federation showed that the Russian population in long-term dynamics due to low income is not balanced. In addition, the reduction of disposable income over the past 6 years leads to a change in the structure of consumption towards an increase in the share of cheap poor-quality products. Thus, the issue of ensuring food security remains relevant and paramountable at the state level.
Implementation of government support measures for reclamation as an incentive for the development of the agricultural industry: Experience of the Republic of Tatarstan
Authors: Khismatullin Marsel , Mukhametgaliev Farit , Asadullin Nail , Avkhadiev Fayaz , Khismatullin Mars , Raheem Ullah
Published: October 2021

The article discusses the issue of government support for reclamation activities in the context of new challenges of the economic environment. The relevance of the issue is due to the need for intensive development of the agricultural sector caused by globalization processes, which have created fierce competition, both in the international and domestic food markets. Sustainable production of agricultural products on irrigated lands is one of the main indicators of the efficiency of the agro-industrial complex in areas of risky agriculture, including the Republic of Tatarstan. The purpose of the article is to develop recommendations for improving the efficiency of irrigated agriculture whose development depends on the stability of agricultural production and food security. The study aims to identify trends in the development of land reclamation at the regional level and substantiate measures aimed to improve the economic efficiency. The paper presents results of the analysis of development of land reclamation in the Republic of Tatarstan, identifies directions of its development, provides recommendations for ensuring sustainable growth in the volume of reclaimed land and agricultural products, income from the sale of products obtained through irrigation. The research results can be used to develop programs aimed at the development of federal and regional food markets, organizational, economic, technological measures to improve the efficiency of agricultural production, rural areas and the provision of high-quality food supply to the population.
The causes of alimentary infertility of highly productive cows and prevention measures
Authors: Mikhailova Irina , Leshchenko Tatiana , Evlevsky Alexey , Ortyakova Irina
Published: October 2021

In recent years, in connection with the importation of highly productive imported livestock into the territory of the Russian Federation, reproduction issues have become especially acute and have become an urgent problem of dairy cattle breeding. Their solution will ensure stable production of irreplaceable food products for the population of the country. According to many researchers, the most common cause of infertility in cows is metabolic disorders due to unbalanced feeding with a predominance of concentrated feed in the diet. As a result, in deeply pregnant and calving cows, pathobiochemical processes reach critical values, and a large number of animals are culled immediately after calving or in the first months of lactation. In the rest of the cows, reproductive disorders are observed and alimentary infertility develops. In order to correct metabolic processes and restore the reproduction function in cows, we proposed an energy-metabolic composition based on glycerol and succinic acid or sodium succinate. To determine its effectiveness, an experiment was carried out, as a result of which a high therapeutic efficacy of the drug was established, which was confirmed by the data of a biochemical study of the blood of experimental cows. Reproductive ability was restored in 85.6% of the cows of the experimental groups, which were fed with the proposed drug. In the control group, only 78.2% of the animals came in heat within 90 days after calving. Thus, the experiment has proven the effectiveness of the use of the energy-metabolic composition (glycerol with succinic acid or sodium succinate) for the correction of pathobiochemical processes and the preservation of the reproductive capacity of cows.
Technology selection for cultivation of sunflower hybrids in Central Black Earth region
Authors: Zasorina Elsa , Komaritskaya Elena , Ishkov Igor , Titov Alexey
Published: October 2021

This study applies a number of technologies to cultivation of sunflower hybrids with variable soil properties, weather conditions and farm locations in Central Black Earth: Kursk, Orel and Voronezh regions. The three-year research identified reactions of sunflower hybrids from different manufacturers to cultivation technology and weather conditions; we made relevant observations; analysed yield structure, yield and seed quality parameters; forecast prospects of using CLEARFIELD and ExpressSun technologies for sunflower cultivation in Central Black Earth region. Overall, the experiment revealed the advantage of CLEARFIELD® (EURO-LIGHTNING®) technology in Kursk region. Hybrids from main producers had a superior average result compared to the standard hybrid SI Bacardi (Syngenta) over three years of research: this is an increase of 0.6 t/ha or 24% (hybrid P64LC108), 1.3 t/ha or 52% (hybrid EC Generalis), and 0.9 t/ha or 36% (hybrid MAS 89 IR).In Orel region hybrids cultivated with ExpressSun (Express® 75 v.y.) or Sumo showed better performance. The hybrid P62LE122 gave an increase of 0.4 t/ha or 20% and the hybrid EC Argentic - 0.3 t/ha or 15% compared to the standard hybrid Sumiko (Syngenta). In Voronezh region hybrids cultivated by ExpressSun (Express ® 75 v.y.) or Sumo technology had yield advantage. Increases were between 0.5 and 1.0 t/ha, or between 15 and 29%, depending on the sunflower hybrid cultivated
The effectiveness of technologies for the cultivation of winter wheat with different levels of biologization in the conditions of the Kursk region
Authors: Nikitina Oksana , Lazarev Vladimir , Stifeev Anatoly
Published: October 2021

The results of studies on the efficiency of winter wheat cultivation technologies, including fertilization systems with different levels of biologization, are presented. It was found that during the cultivation of winter wheat using intensive technology with a mineral fertilization system, the reserves of productive moisture in the arable layer of the soil were almost equal to the reserves of moisture when cultivated using intensive technology (without fertilization). In variants with the cultivation of winter wheat according to the technology with a 50% level of biologization, the reserves of productive moisture in the arable layer of the soil increased by 0.9 mm, and by a 100% level - by 1.6 mm. Higher reserves of nitrate-nitrogen in the 0-40 cm soil layer before sowing winter wheat were noted in variants where it was cultivated using biotechnology with a 100% supply of nutrients from organic fertilizers. A decrease in the level of biologization of the technology to 50% led to a decrease in the reserves of nitrate-nitrogen by 2.5 kg/ha. The highest weediness of winter wheat crops was noted when it was cultivated using technologies with 50 and 100% biologization levels - 70.6-92.0 pcs/m2. Compared to the mineral fertilization system, when using organic fertilizers, there is an increase in weediness of winter wheat crops by 5.8-18.1%. The highest yield of winter wheat was obtained by cultivating it using intensive technology - 5.98 t/ha. Technologies with 50 and 100% biologization levels ensured the production of 5.87 and 5.41 t/ha, respectively.
Improving the technological support of dairy cattle breeding
Authors: Kondratieva Olga , Fedorov Anatoly , Slinko Olesya , Voytyuk Vyacheslav
Published: October 2021

The paper discusses the issues of providing the population of the Russian Federation with milk and dairy products, increasing milk production, and implementing investment projects in the industry. It is noted that the technological and technical support, as well as improving the systems of keeping, feeding and milking animals play an important role in solving problems of increasing the efficiency of dairy farming. Particular attention is paid to the introduction of innovative technologies and modern machinery at dairy farms and facilities, including equipment fitted with digital systems for collecting information about the state of animals, milk yield, milking parameters and other indicators, as well as robots. Milking installations provided by the system of machines are designed for milking cows in stalls, milking parlors, as well as in maternity wards. According to their engineering level, they must ensure the fulfillment of the physiological milk let-down requirements, the productive longevity of animals, etc. The developed artificial intelligence system allows planning the efficiency of feeding and monitoring the main processes at a dairy farm. Feed is of paramount importance in the prime cost of raw milk. The cost of feed affects the profitability of production. Spectrometers, including pocket ones, can be used for feed analysis. Improvement of technologies in dairy production will help to increase the competitiveness of the industry.
Breeding beef calves using different feeding technologies
Authors: Trukhachev Vladimir , Oliinyk Serhii , Kozyr Vladimir , Zlydnev Nikolay , Pokotilo Alexey
Published: October 2021

The article presents the findings on the dynamics of the live weight of calves of various breeds in similar climatic conditions in arid regions of the Stavropol Krai of Russia and the steppe zone of Ukraine. It has been established that the live weight of calves of the Hereford, Kazakh white-headed and Kalmyk breeds when raised according to the traditional technology of beef cattle breeding when calves are sucked under cows up to 6-7 months of age, is in relationship with the milk qualities of mothers. At the same time, the live weight of the gray Ukrainian calves was interrelated regarding the live weight at birth and the feeding technology. A positive relationship was shown in the live weight of calves at birth and during their implementation at 15 and 18 months of age. Most effectively animals used pasture fodder in spring and summer. In an arid climate, it is more appropriate to breed specialized cattle belonging to the Hereford breed and then sell them for breeding in other farms in the region.
Crop contamination and spring wheat yield depending on the systems of pre-sowing tillage
Authors: Kuzminykh Albert , Novoselov Sergey , Pashkova Galina
Published: October 2021

This research has been conducted to study the influence of pre-sowing tillage methods on the crop contamination and spring wheat yield. It has been established that the use of continuous cultivation in the system of pre-sowing tillage contributes to the reduction of crop contamination by 21.2-45.1 %. That allowed obtaining a higher grain yield of 2.48-2.54 t/ha with a protein content of 11.74-11.80 %. The gluten was 25.0-25.4 % of the first quality group and with a vitreous content of 53.2-54.4 %.
Efficiency of blood “refreshing” method in cattle pure breeding of the Simmental breed
Authors: Lamonov Sergey Aleksandrovich , Skorkina Irina Alekseevna
Published: October 2021

Over the past two decades, pedigree cattle and sperm products have been imported into the Russian Federation from outstanding breeding bulls of the Simmental breed from Western Europe, including Austria, within the framework of the “AIC Development” national project. Specific productive and technological qualities are inherent in these animals due to the direction peculiarities of selection and breeding work with this breed in Austria. World experience has clearly proved that the future belongs to large dairy complexes and farms, which are fully mechanized and automated. Modern Simmental cattle (mostly cows) do not meet the requirements of intensive milk production technology for a number of productive and technological characteristics. Summarizing the world zootechnical experience, it is possible to determine the basic requirements for cows suitable for operation in conditions of advanced milk production technologies. Based on numerous studies, these animals are characterized by high milk production, good reproductive qualities, suitable for machine milking, with strong hoof horn, resistant to diseases and mastitis. Consequently, a significant role is given to the manning of a milking herd with highly productive and competitive Simmental cows, obtained as a result of improving the system of selection and breeding work to further increase the production of marketable milk. The conducted research result shows zootechnical efficiency of using such a breeding method as “refreshing” blood in the breeding process. In particular, the best indicators of milk yield for the first lactation are observed in cows descended from bullsproducers of Austrian selection, -4153.1 kg of natural fat milk. The morphological and functional characteristics of the udders of all experimental first-calf cows meet the requirements of suitability for machine milking. Cows of the Simmental breed obtained by the method of “blood refreshing” are the most cost-effective in the same conditions of feeding and keeping.
Optimisation of repair and maintenance costs for electrical equipment in agricultural enterprises
Authors: Zhdanov Valery , Logacheva Elena , Yarosh Viktor , Ivashina Alexander
Published: October 2021

Application of mathematical methods of cost optimization for repair and maintenance of electrical equipment of agro-industrial enterprises is one of the important and promising directions for increasing the efficiency of electrical equipment operation management in agriculture. Mathematical programming systems use graphical and related attributive information in solving optimization problems. As graphical information in these systems we used maps, plans, diagrams, schedules of preventive measures from which the list of equipment for certain types of repair and maintenance, their labor intensity for individual objects, types of equipment and in total for the enterprise are established. Databases of electrical equipment are used as attributive information to describe electrical equipment of agro-industrial enterprises. Due to joint processing of graphical and attributive information in optimization systems, all stages of work with spatial data are more operative. Beginning from spatial data search, selection and analysis we can make a specific decision during the operation control of electrical equipment. This article considers maintenance and repair operation (MR) as a task of mathematical programming with cost optimization and deals with three approaches to the organization of this task. The expediency of using each method of solution is analyzed. The structural schemes, equations describing mathematical models, advantages and disadvantages of the presented models are given. We marked prospect of using linear programming programs for the decision of the given optimization problem by means of the inverse matrix method, i.e. the modified simplex method and computing algorithm with a standard sequence of operations.
Honey Quality and Safety Control in The Altai Territory
Authors: Lunyova Nadezhda , Razumovskaya Valentina , Kronevald Olga , Dutova Olga
Published: October 2021

Due to a number of factors, “Altai honey” is a branded product. The article describes factors that affect the quality and safety of honey in the Altai Territory. Honey samples taken in different municipal districts of the Altai Territory were tested. It was concluded that organoleptic indicators, quality and safety indicators, the presence of toxic elements, radionuclides and medicines correspond to the regulatory documents. Counterfeit honey is not supplied to the markets and food fairs of the region; however, there were honey samples with poor physical and chemical characteristics, which indicates the early harvest of honey and the untimely use of means for preventing and treating infectious diseases in bee colonies. The well-being of apiaries is registered in veterinary and sanitary passports, which are issued by the state veterinary service in agreement with the owner. The epizootological monitoring revealed that among infectious diseases, nosematosis, aspergillosis and varroatosis are more common.