bluuebunny/crossref_metadata_2025 huggingface dataset:
A Study Against Colon Cancer Mechanism of Xanthium sibiricum Herba
Based on Computer Simulation and Bioinformatics
Authors: Qi Ying , Cai Jia-Han , Deng Qiu-Tong , Zeng Yuan-Ning , Wang Qiu-Hong
Published: May 2023

Introduction:

Cancer is one of the leading causes of death worldwide, accounting for
nearly one in six deaths in 2020. As a folk medicine, Xanthium sibiricum Herba (XSH) has been
used many times in clinical practice for the treatment of various diseases. With the increasing
number of cancer patients, there is a clinical need to find effective anti-cancer drugs.

Aim:

This study aims to explores the bioactivity and the anti-cancer mechanism of XSH.

Methods:

In this study, bioinformatics, network pharmacology, molecular docking, molecular dynamics
simulation techniques, and apoptosis assay were used to explore the bioactivity and the anti-
cancer mechanism of XSH.

Results:

Finally, seven active ingredients in XSH after the screening were obtained, the two most
active compounds were β-sitosterol and aloe-emodin, and good anti-cancer activity of XSH was
predicted.

Discussion:

Four core targets were obtained from the PPI network map, namely Caspase-3
(CASP3), Transcription factor AP-1 (JUN), Myc proto-oncogene protein (MYC), and cellular tumor
antigen p53 (TP53). GO and KEGG analyses showed that the mechanism of XSH anti-cancer
is mainly related to the apoptosis process, and the main signaling pathways are enriched in the p53
signaling pathway, Apoptosis, and MAPK signaling. The molecular docking and molecular dynamics
simulation results showed that CASP3, JUN, MYC, and TP53 had a high affinity with β-
sitosterol and aloe-emodin. Bioinformatics analyses demonstrated the importance of core targets.
Apoptosis assay showed that XSH could significantly promote the apoptosis of cancer cells, and
inhibit their proliferation and migration, especially colon cancer cells.

Conclusion:

This study uncovered the main active components, bioactivities, and potential targets
of XSH, and further revealed the multi-component, multi-target, and multi-pathway mechanism of
XSH for cancer treatment and promoting apoptosis.
Connectivity between Gut Microbiota and Terminal Awakenings in
Alzheimer’s Disease
Authors: Bostancıklıoğlu Mehmet
Published: May 2023

Memory is empirically described as a brain function that connects the past to the present.
This reductionist approach has focused on memory function within neurons and synapses, leading to
an understanding that memory loss in dementia is caused by irreversible neuronal damage. However,
recent palliative case reports and the Human Connectome Project have challenged the "irreversible"
paradigm by indicating that some demented patients are able to retrieve supposed ‘lost’ memories
and cognitive functions near death. The serotonin-centric hypothesis and the lifelong oligodendrocyte
differentiation capacity may explain terminal awakening symptoms in these patients. Furthermore, an
increased rate of serotonin-secreting and oligodendrocyte precursor cell-triggering gut bacteria near
death temporally correlates with lucid improvements in demented patients. These findings may shift
the context of terminal memory retrieval from a purely neuronal to a systemic idea that bridges terminal
lucidity and gut microbiota. In this review, we take the systemic approach further and point out
a temporal correlation between the gut microbiome and terminal lucid episodes in Alzheimer’s patients.
Predicting Herb-disease Associations Through Graph Convolutional
Network
Authors: Hu Xuan , Lu You , Tian Geng , Bing Pingping , Wang Bing , He Binsheng
Published: May 2023

Background:

In recent years, herbs have become very popular worldwide as a form of complementary
and alternative medicine (CAM). However, there are many types of herbs and diseases,
whose associations are impossible to be fully revealed. Identifying new therapeutic indications of herbs,
that is drug repositioning, is a critical supplement for new drug development. Considering that exploring
the associations between herbs and diseases by wet-lab techniques is time-consuming and laborious,
there is an urgent need for reliable computational methods to fill this gap.

:

In this study, we first preprocessed the herbs and their indications in the TCM-Suit database, a comprehensive,
accurate, and integrated traditional Chinese medicine database, to obtain the herb-disease association
network. We then proposed a novel model based on a graph convolution network (GCN) to infer
potential new associations between herbs and diseases.

Methods:

In our method, the effective features of herbs and diseases were extracted through multi-layer
GCN, then the layer attention mechanism was introduced to combine the features learned from multiple
GCN layers, and jump connections were added to reduce the over-smoothing phenomenon caused by
multi-layer GCN stacking. Finally, the recovered herb-disease association network was generated by the
bilinear decoder. We applied our model together with four other methods (including SCMFDD, BNNR,
LRMCMDA, and DRHGCN) to predict herb-disease associations. Compared with all other methods,
our model showed the highest area under the receiver operating characteristic curve (AUROC), the area
under the precision-recall curve (AUPRC), as well as the highest recall in the five-fold cross-validation.

Conclusion:

We further used our model to predict the candidate herbs for Alzheimer's disease and
found the compounds mediating herbs and diseases through the herb-compound-gene-disease network.
The relevant literature also confirmed our findings.
Mechanical Properties and Molecular Transport Behavior of NR/Clay and
ENR/Clay Composites
Authors: Reghunath Rakesh , Mathew Aji P. , George Soney C.
Published: May 2023

Introduction:

Natural rubber and epoxidized natural rubber composites reinforced with
clay have been synthesized in this study using two roll mixing mill.

Objective:

The aim of the research work was to investigate the influence of clay on the overall performance
of NR and ENR based composites.

Methods:

The effect of clay concentration on basic mechanical properties and molecular transport
phenomena of the elastomeric composites was analyzed. Tensile strength and tear strength variation
as a function of clay concentration were studied.

Results:

It was found that as clay concentration increased up to 4 phr, tensile strength improved up
to 22.5 MPa and tear strength up to 32 MPa, beyond which it went down. It was also found that
corresponding to 4 phr clay concentrations, the crosslink density of the composite was at a maximum
of 1.45 gmol/cc.

Conclusion:

As the clay contents are added into the elastomeric matrix system, initially there is a
decrease in the swelling coefficient, but later at higher loading, the swelling coefficient increases
due to the agglomeration of clay particles in the matrix.
Finite Element Analysis of Reinforced Concrete Beams Strengthened with
Hybrid Fiber Reinforced Polymer Systems using ANSYS
Authors: Gurram Kalyani , N. Pannirselvam
Published: May 2023

Background:

Existing reinforced concrete (RC) structures can deteriorate over time
due to aging, poor construction design, natural disasters, etc. In recent years, fiber-reinforced polymer
(FRP) composite materials are becoming a preferred choice for concrete construction repair
due to their durability, high strength, and corrosion resistance. This study aimed to study and analyze
the properties of the constituent materials to identify any weaknesses and potential improvements.

Methods:

The present study investigated the effectiveness of flexural strengthening of RC beams
using a hybrid grouping of glass-FRP (GFRP) and carbon-FRP (CFRP) unidirectional laminates.
ANSYS finite element analysis (FE) software was used to investigate the failure modes of the
beams and the stress-strain parameters. The impact of adopting two different grades of reinforcing
bars in RC beam modeling was also contrasted in the study.

Results:

Comparisons between the finite element analysis and experimental literature results were
made. Based on the test findings, it could be concluded that retrofitted beams perform better than
non-retrofitted beams. According to experimental results, the HY14 sheet enhanced beam had a
188.46% higher ultimate load than the unenhanced beams.

Conclusion:

Comparing experimental findings to the conclusions of the numerical analysis, a
maximum difference of ultimate load and deflection at mid-span of 3.40% and 4.91%, respectively,
were used to assess the accuracy of the results.
Efficacy and safety of local application of Vijaya oil in the management of Sandhivata with special reference to Osteoarthrosis: An open-labeled single-arm clinical trial
Authors: Akhlak Shehla , Pawankumar Godatwar , Preeti Gavali , Reetu Sharma , Neeraj Patel , Jahan James Peston , Kalpana Dhuri
Published: May 2023

Background: Osteoarthrosis is the second most common rheumatologic problem in India. Symptoms of Osteoarthrosis resemble Sandhivata in Ayurveda. Vijaya (cannabis sativa) oil manufactured by Bombay Hemp Company is used as a topical application in patients suffering from Sandhivata. Aim: To evaluate the efficacy & safety of local application of Vijaya oil in patients suffering from Sandhivata, with special reference to Osteoarthrosis. Materials and methods: Present clinical study was an open-label, single-arm study for the management of Sandhivata aged 30-75. The oil was applied locally on the affected site for 2 months. A total of 42 eligible patients suffering from symptomatic OA were enrolled, and 40 completed the study. Patients were assessed by clinical sign and symptom score for Sandhivata, Visual Analog Scale for Pain (VAS), WOMAC score for pain, stiffness, and physical function difficulty, Quality of life (QOL) score, Global assessment scale (GAS), and Overall disease severity (ODS). Statistical analysis was done by the Wilcoxon test. Results: The result was highly significant for all the subjective parameters. Conclusion: The study revealed that Vijaya oil significantly reduced pain, and stiffness, improved quality of life, and physical functions. It could be concluded that Vijaya oil can be a used as safe and effective drug of choice in patients suffering from Sandhivata.
An evaluation of pharmacological actions of Padmak Agada: A Review
Authors: Varsha Bansal  , Ramesh Chandra Tiwari  , Manisha Dikshit  , Ved Bhushan Sharma  , Bhawana Mittal
Published: May 2023

Agada means the medicaments which have antitoxic properties. They are used to combat Gada which means disease, discomforts, pain, or morbid conditions produced by any type of the poison. For the management of different poisons many formulations are mentioned in Ayurveda. Acharaya Vagbhatta has mentioned so many formulations in Keetlootadivishpratishedham Adhyay of Ashtanghrudayam Uttarsthana. One of those formulation is Padmakagada, which is indicated in the treatment of all types of insect bite (Keet Visha and Loota Visha). Padmakagada can be used in different forms like Nasya (Nasal instillation), Dhoom (medicated smoke), Abhyanga (massage), Paan (drink) etc. It contains 5 ingredients including Priyangu, Haridra, Daruharidra, ghee and honey. Easy availability of its ingredients and simplicity of the preparation and preservation of the formulation may encourage the physician to use this formulation. Here is an effort has been made to review Padmak Agada in order to its pharmacological properties for its medicinal use.
Role of Shatapushpa Taila oral use in Vandhya w.s.r. to PCOS - Retrospective case series
Authors: Priyanka T K
Published: May 2023

Infertility is a fast emerging global disease and is at its peak incidence worldwide due to faulty diet and lifestyle of this era. It is defined as the inability of a couple to achieve conception after one year of unprotected coitus. This condition may be further classified as primary infertility, in which no previous pregnancies have occurred, and secondary infertility, in which a prior pregnancy, although not necessarily a live birth, has occurred. Most couples are more correctly considered to be subfertile, rather than infertile, because they will ultimately conceive if given enough time. Most couples presenting with a fertility problem will not be having absolute infertility, but rather relative subfertility with a reduced chance of conception because of one or more factors in either or both partners. This concept of subfertility can be reassuring to couples too. Disorders of ovulation account for about 30% to 40% of all cases of female infertility and are generally among the most easily diagnosed and most treatable causes of infertility. Shatapushpa is one among the best drugs in management of Vandhya due to ovulatory dysfunction owing to the properties described. Even a Vandhya or Shanda can deliver a child, on consumption of Shatapushpa signifies its prime role. Control of Vata Dosha is the principal step in management of female reproductive system disorders. Taila is the best medium for control of Vata. An attempt is made to evaluate the role of Shatapushpa Taila in Vandhya management wsr to PCOS with aid of case series.
Koordinasi Rellay Pada System Kelistrikan Kapal Bulk Carrier 50.000 DWT (Dead Weight Ton) Berbasis ANFIS
Authors: Arohman Eki , Prasetyo Johan
Published: May 2023

Abstrakâ€“-Semakin pesat kecanggihan dunia kemaritiman Era sekarang sehingga pembaruan teknologi disetiap bagian sangat berperan terhadap kemajuan kapal, yang terutama berhubungan dengan kelistrikan pada kapal sebagai penunjang keandalan pada keamanan kapal dapat dioptimalkan dan menghindari gangguan kelistrikan pada kapal bulk carrier 50.000 Dwt, Sehingga menggunakan plant sistem distribusi kelistrikan pada kapal digunakan koordinasi relay yang menggunakan sistem inferensi Fuzzy digabungkan dengan arsitektur sistem jaringan syaraf tiruan diimplementasikan pada kapal bulk carrier 50.000Dwt, Hasil dari penelitian ini setting menggunakan metode Anfis Â dapat mewakili perhitungan konvensional yang dibuktikan dengan pengujian setting fuzzy pada plant kapal bulk carrier 50.000 dwt menggunakan tool star protection pada etap 6.0.0 untuk koordinasi relay pada saat hubung singkat minimum pada bus 2 dan bus 103, grading time antar relay diberikan sebesar 0,2 dan 0,3 detik.
Emerging Roles of Signal Transduction Pathways in Neurodegenerative Diseases. Hunting New Possible Therapeutic Molecular Targets
Authors: Lo Vasco Vincenza Rita
Published: May 2023

Illnesses following the degeneration of the nervous system can occur due to aging or genetic mutations and represent a clinical concern. In neurodegenerative diseases, loss of neuronal structure and functions mainly causes cognitive impairment, representing an increasing social burden. In neurodegenerative diseases, the progressive loss of vulnerable populations of neurons in specific regions of the central nervous system was traced to different pathological events, such as misfolded proteins’ accumulation, abnormalities in proteasomes or phagosomes, as well as anomalies in lysosomes or mitochondria. Many research efforts identified important events involved in neurodegeneration, but the complex pathogenesis of neurodegenerative diseases is far from being fully elucidated. More recently, insights into the signal transduction pathways acting in the nervous system contributed to unveiling some molecular mechanisms triggering neurodegeneration. Abnormalities in the intra- or inter-cellular signaling were described to be involved in the pathogenesis of neurodegenerative disease. Understanding the signal transduction pathways that impact the nervous system homeostasis can offer a wide panel of potential targets for modulating therapeutic approaches. The present review will discuss the main signal transduction pathways involved in neurodegenerative disorders.
User Compliance With the Health Emergency and Disaster Management System: Systematic Literature Review
Authors: Fitriani Widia Resti , Sutanto Juliana , Handayani Putu Wuri , Hidayanto Achmad Nizar
Published: May 2023

Background

Health-related hazards have a detrimental impact on society. The health emergency and disaster management system (Health EDMS), such as a contact-tracing application, is used to respond to and cope with health-related hazards. User compliance with Health EDMS warnings is key to its success. However, it was reported that user compliance with such a system remains low.

Objective

Through a systematic literature review, this study aims to identify the theories and corresponding factors that explain user compliance with the warning message provided by Health EDMS.

Methods

The systematic literature review was conducted using Preferred Reporting Items for Systematic reviews and Meta-Analyses 2020 guidelines. The search was performed using the online databases Scopus, ScienceDirect, ProQuest, IEEE, and PubMed, for English journal papers published between January 2000 and February 2022.

Results

A total of 14 papers were selected for the review based on our inclusion and exclusion criteria. Previous research adopted 6 theories when examining user compliance, and central to the research was Health EDMS. To better understand Health EDMS, based on the literature reviewed, we mapped the activities and features of Health EDMS with the key stakeholders involved. We identified features that require involvement from individual users, which are surveillance and monitoring features and medical care and logistic assistance features. We then proposed a framework showing the individual, technological, and social influencing factors of the use of these features, which in turn affects compliance with the warning message from Health EDMS.

Conclusions

Research on the Health EDMS topic increased rapidly in 2021 due to the COVID-19 pandemic. An in-depth understanding of Health EDMS and user compliance before designing the system is essential for governments and developers to increase the effectiveness of Health EDMS. Through a systematic literature review, this study proposed a research framework and identified research gaps for future research on this topic.
Adverse Effects of Virtual and Augmented Reality Interventions in Psychiatry: Systematic Review
Authors: Lundin Robert M , Yeap Yuhern , Menkes David B
Published: May 2023

Background

Virtual reality (VR) and augmented reality (AR) are emerging treatment modalities in psychiatry, which are capable of producing clinical outcomes broadly comparable to those achieved with standard psychotherapies.

Objective

Because the side effect profile associated with the clinical use of VR and AR remains largely unknown, we systematically reviewed available evidence of their adverse effects.

Methods

A systematic review was conducted in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) framework across 3 mental health databases (PubMed, PsycINFO, and Embase) to identify VR and AR interventions targeting mental health diagnoses.

Results

Of 73 studies meeting the inclusion criteria, 7 reported worsening clinical symptoms or an increased fall risk. Another 21 studies reported “no adverse effects” but failed to identify obvious adverse effects, mainly cybersickness, documented in their results. More concerningly, 45 of the 73 studies made no mention of adverse effects whatsoever.

Conclusions

An appropriate screening tool would help ensure that VR adverse effects are correctly identified and reported.
Computer-aided, Evidence-based System Improved Clinical Diagnostic Accuracy of Certificated-Physicians in Acute Abdominal Pain (Preprint)
Authors: Yao Liwen , Wang Jing , Zhang Chenxia , Wu Zhifeng , Luo Chaijie , Zhang Lihui , Xiao Bing , Gong Rongrong , Dong Zehua , Huang Li , Zhou Zhongyin , Lu Zihua , Sharma Prateek , Lin Rong , Liu Mei , Yu Honggang
Published: May 2023

BACKGROUND

Acute abdominal pain (AAP) is a common complaint and can be caused by a broad spectrum of diseases. Mis-diagnosis or delay can lead to severe complications and increased mortality. The diagnostic performance of AAP remains sub-optimal.

OBJECTIVE

We aimed to develop an artificial intelligence (AI) system for AAP diagnosis, and to evaluate the efficacy of the system.

METHODS

The system consisted of 164 feature extraction models and 1 disease prediction model. The system will first match the extracted features with the pretherapeutic/preoperative diagnostic criteria for each AAP disease and output the corresponding diagnose. If none of the criteria was matched, the system will make a feature-based fitting for clinical diagnosis prediction. Pre-training, training and validation of the system included 65,933, 2766 and 607 AAP patients, respectively. A randomized control reader study was conducted including 22 physicians, 11 in the AI-assist group and 11 in the control group to further evaluate the performance of system.

RESULTS

The average accuracy for feature extraction was 97.52%. For disease prediction, the system achieved accuracy of 84.18% for clinical diagnosis. In the reader study, both accuracies of clinical diagnosis and final diagnosis were significantly higher in AI-assisted group compared to control group (81.40% vs 69.49%, P＜0.001, OR=0.511, 95% CI. = 0.225-0.797; 92.54% vs 86.27%, P＜0.001, OR=0.518, 95% CI. = 0.133-0.258, respectively).

CONCLUSIONS

The system achieved an excellent performance in predicting AAP diseases and has great potential to become a clinically useful diagnostic aid in AAP diagnosis.
How does ChatGPT4 preform on Non-English National Medical Licensing Examination? An Evaluation in Chinese Language (Preprint)
Authors: Fang Changchang , Ling Jitao , Zhou Jing , Wang Yue , Liu Xiaolin , Jiang Yuan , Wu Yifan , Chen Yixuan , Zhu Zhichen , Ma Jianyong , Yan Ziwei , Yu Peng , Liu Xiao
Published: May 2023

BACKGROUND

ChatGPT, an artificial intelligence (AI) system powered by large-scale language models, has garnered significant interest in the healthcare. Its performance dependent on the quality and amount of training data available for specific language. This study aims to assess the of ChatGPT's ability in medical education and clinical decision-making within the Chinese context.

OBJECTIVE

Evaluate ChatGPT's performance on the Chinese NMLE conducted within the Chinese context.

METHODS

We utilized a dataset from the Chinese National Medical Licensing Examination (NMLE) to assess ChatGPT-4's proficiency in medical knowledge within the Chinese language. Performance indicators, including score, accuracy, and concordance (confirmation of answers through explanation), were employed to evaluate ChatGPT's effectiveness in both original and encoded medical questions. Additionally, we translated the original Chinese questions into English to explore potential avenues for improvement.

RESULTS

ChatGPT scored 442/600 for original questions in Chinese, surpassing the passing threshold of 360/600. However, ChatGPT demonstrated reduced accuracy in addressing open-ended questions, with an overall accuracy rate of 47.7%. Despite this, ChatGPT displayed commendable consistency, achieving a 75% concordance rate across all case analysis questions. Moreover, translating Chinese case analysis questions into English yielded only marginal improvements in ChatGPT's performance (P =0.728).

CONCLUSIONS

ChatGPT exhibits remarkable precision and reliability when handling the NMLE in Chinese language. Translation of NMLE questions from Chinese to English does not yield an improvement in ChatGPT's performance.
Involving Parents and Community Leaders to Promote College and Career Aspirations among Refugee Youth
Authors: Judson Eugene , Hailu Meseret , Ibrahim Mohammed
Published: May 2023

Among challenges of refugee students attempting to pursue ambitions to attend a university and subsequently take up a professional career, are uncertainty about how to navigate from high school to college and unawareness of career fields. In this paper, we report on results of a project focused on promoting STEM aspirations and understanding college navigation among refugee families in the United States. Through partnerships between refugee community organizations and a university, families participated in workshops that included learning about a breadth of STEM careers and how to chart a successful course from secondary to postsecondary education.
Experimental study of the characterization of household waste in Bamako, Mali
Authors: Adamou Mohamadou , Maiga Mohamed S , Cissé Oumar , Sagara Joseph Amadomon , Ouattara Yaya
Published: May 2023

In Bamako, the flow of household waste and its typology are little known. In order to set up a sustainable management system for the city's garbage, it is nevertheless important to know the quantities, natures and dimensions of the objects that make up the garbage. This study, which began in 2017, consisted of characterizing the garbage collected at the household level in Bamako using the MODECOM method modified to adapt it to the Malian context. The objective of this study was to propose a method intended to obtain solid results on the characteristics of household waste produced in Bamako in order to build adapted collection and recovery strategies. The results, obtained from a sample of 270 households in the 6 communes of Bamako and 3 neighborhoods of different socio-economic levels per commune, showed that the average ratio of household waste produced in Bamako is about 0.28 Kg per inhabitant per day. The category of fines is the most important, with an average daily production of 2.45 kg for a household with an average of 20.5 inhabitants. Putrescibles come in second place. Their production represents 41% of the average amount of garbage generated in a high standard household. It represents the main biodegradable category of garbage. Fines, which are mostly sand, charcoal and ash, accounted for 37 percent of the waste generated by households of the same type. The particle size sorting, which can help to choose suitable industrial sorting tools, shows that the fraction of medium-sized garbage is the most abundant. The data from the characterization of garbage would allow the development of all forms of garbage management strategies, especially for its collection and recovery.
El papel de la historia en la filosofía hermenéutica: Gianni Vattimo y Charles Taylor
Authors: Saiz Mauro Javier
Published: May 2023

El presente artículo busca aproximarse al papel que la historia —como realidad y como conocimiento— ocupa en la filosofía hermenéutica. Para ello, se aborda la teoría de dos exponentes contemporáneos de dicha tradición: Gianni Vattimo y Charles Taylor. A partir de una exposición sintética de la propuesta de ambos autores, tanto en un plano epistemológico como en el de su interpretación puntual de la época contemporánea, se pretende identificar similitudes y diferencias entre ambos modelos. Posteriormente, a través de una comparación crítica, se resaltan las debilidades y posibles contradicciones de cada planteamiento. En la conclusión, se busca defender la superioridad de la aproximación tayloreana al conocimiento histórico, en la medida que respeta de manera más consistente la pluralidad de interpretaciones de los procesos y eventos, al tiempo que deja abierta la vía para una evaluación moral y política normativa.
Las ciencias sociales y la historia: dialéctica de tiempos y metodologías
Authors: Bokser Misses-Liwerant Judit
Published: May 2023

Para la Revista Mexicana de Ciencias Políticas y Sociales resulta fundamental articular un espacio de discusión sobre investigaciones actuales y reinterpretaciones de académicas y académicos sobre la disciplina histórica. La revisión que los artículos incluidos en nuestro dossier hacen de eventos históricos o de sus epistemologías y metodologías genera cuestionamientos contemporáneos y de vanguardia sobre “la escritura de la historia” como diría Michel de Certeau. Estas expresiones conceptuales y empíricas dan cuenta de la diversidad de problemáticas que se revitalizan para configurar nuevas miradas de, desde y hacia la historia. Por ello, en los artículos el dossier de este número 248, titulado “Escenarios políticos y reordenamientos conceptuales de la historia: nuevas miradas al pasado y al presente”, se conjuntan temáticas importantes de esta disciplina que entrecruzan, tangencial o directamente, a otras ciencias sociales y humanidades.
Web Based Portal for Complete Data Engineering
Authors: Dwivedi Prashant , Jadhav Shreyas , Jadhav Shruti , Singh Dr. Vidyadhari
Published: May 2023

Abstract: Machine Learning has become the need of today’s world. Any intelligent system is incomplete without Machine Learning. People use ML models in various applications. Every ML-based project has to go through some of the steps during the development process. This process consists of certain common steps which every ML project needs to follow. The process of building ML models is tedious and time consuming. There are some common problems which people face while developing MLbased projects. That includes lack of resources and infrastructure, lack of uniformity in codebase and writing repetitive code for every project. These problems are very serious as building ML models needs a lot of effort and time. This paper aims to describe some of the problems that people face during the development of ML-based projects. It also provides a solution to reduce many problems and save efforts in the development process. The system proposed in this paper can save a lot of time and effort in building ML models. It will help to build projects faster and increase efficiency.
A Secure Messaging Application with Unbreakable End to End Encryption
Authors: Harshvardhan Bawake , Saideep Cholke , Atharv Dhole , Ankit Jadhav , Bhise Prof. Arti
Published: May 2023

Abstract: Instant messaging services on mobile devices, such as WhatsApp, have become immensely popular, largely due to their end-to-end encryption (E2EE) feature, which ensures user privacy. However, this has raised concerns for some governments who argue that E2EE makes it challenging to combat terrorism and organized crime. These governments have expressed the desire for a "backdoor" to access messages in cases of credible threats to national security. However, WhatsApp users have strongly opposed this idea, citing concerns about privacy infringement and potential exploitation by hackers. This paper presents the advantages of maintaining E2EE in WhatsApp and argues against granting governments a "backdoor" to access user messages. It highlights the benefits of encryption in safeguarding consumer security and privacy, while also acknowledging the challenges it poses to public safety and national security. In the realm of internet messaging security, cryptography plays a crucial role in protecting networks. This paper aims to raise awareness among common computer users about the importance of messaging security and its requirements. Several cryptographic techniques have been developed to achieve secure communication, and the proposed messaging system ensures security in accordance with standard security models
Application of Aeromagnetic Data Analysis and Interpretations to Investigate Solid Mineral Potential in Part of Bauchi, Northeast Nigeria
Authors: Babagana Mustapha , Shehu Fatima M. , Idris El-Yakub A. , Muhammad Ibrahim M. , Suraju Shehu , Nuhu Abubakar , Habib Abdullah , Hamza Fatima Tahir
Published: May 2023

Abstract: The distribution of surface and subsurface magnetic materials within the study area, the delineation of geologic lineaments, and an estimate of the depth to magnetic sources were all determined by interpreting high resolution aeromagnetic data that covered a portion of Bauchi, northeastern Nigeria, lying between Latitudes 9040'00"N to 10010'0"N and Longitudes 900'0"E to 9040'0'E. The Aeromagnetic map, analytical signal, and horizontal derivative filters used on total magnetic intensity data after reduction to the magnetic equator (RTE) show that the Toro and its environs contain highly magnetic minerals thought to be potential deposits of iron ore. The lithological map and the lineament maps have a good connection. Further examination of the findings reveals that the research area has varying degrees of Ferro-, para-, and diamagnetic mineralization (of the iron and non-iron varieties). The geological source bodies are thought to be located between 177.389 and 991.626 meters deep, according to the Euler depth solution. This shows that during the orogenic process, a sequence of strong deformations were present alongside the Toro.
African Identity and Christian Faith in Igboland: A Critical Evaluation of EGWU IMOKA Masquerade Festival
Authors: Abigail Nzoiwu, Azuka , Chekwubechukwu Mmaduabuchi, Obinna
Published: May 2023

bstract: Christianity as a way of life among Africans (The Igbo people precisely) is believed to have shaped and influenced African Culture. African religion and culture according to Okoro, "stand a better chance to offer an alternative method awareness, which is imbedded in different indigenous languages, myths, folklore, cultural heritage and rites and rituals of African traditional faith" (Cultural globalization: 26-37). The identity of the African can be clearly seen in their cultural, anthropological features. The cultural, anthropological features of the Igbo people is influenced by both Christianity and African Traditional Religion. In an attempt to further understand the values behind this cultural influence as it is manifesting itself in the life and thought of the Awka people through Egwuimoka in the contemporary time, the searcher became interested in this- study. However, the influence of culture on Christianity is seen in the attitudinal disposition of the Igbo people towards the Christian faith. Now the question is does Christianity support the Igbo culture which is emerging in the modern time? Does the comparative study of Igbo traditional morality and Christianity ethical concepts clarify a bit of this confused background? if this work helps to answer these and other questions, in any small way, and further helps in clarifying the confused background of our morality today, then, it is not useless effort after all. Our culture is fluid today, because it is rapidly changing. Therefore, this work tries to point to some aspects of the Igbo peoples basis of traditional cultural patterns and beliefs, that can be applied from the values and the beliefs of the past so that the change in culture may not continue on a speed lane and, therefore becoming e confusing as to moral basis of worthwhile existence.
Design of Solar PV for K.K. Wagh Boy’s Hostel
Authors: Talele Swapnil Sunil , Parida Satya Prakash , Suryavanshi Gaurav S.
Published: May 2023

Abstract: It is necessary to simulate and investigate the proper feasibility of Solar PV system at a given location. This study is done to evaluate the feasibility of grid connected rooftop solar photovoltaic system for a K.K. Wagh Institute of Engineering Education and Research, Nashik, India. This paper focuses on the aspects of the design involved in the setup of the system, not only just the design, but also the component such as installation, site evaluation of a given rooftop to the final cost analysis. This paper will give the average understanding of how a rooftop photovoltaic system is been processed.
A Survey on Natural Language to SQL Query Generator
Authors: Gowda Niranjan , Noolee Sinchana S. , Vismaya T , B S Vidyashree
Published: May 2023

Abstract: This paper provides a comprehensive review of a papers which are related to bank application designed for devices, focusing on its features, usability, security, and overall user experience. The application is evaluated based on its ability to perform typical banking tasks, such as checking account balances, transferring funds and managing transactions. The review also examines the application's design, navigation, and user interface, as well as its security features, including authentication, encryption, and protection against unauthorized access. Overall, the review concludes that the bank application is a highly effective and user-friendly tool for managing finances on the go, with robust security measures in place to protect sensitive information.
Antenna Array Double Sequare pada Frekuensi 2.4GHz untuk Sensor Human Vital Nirkabel
Authors: Mujahidin Irfan , Effendy Machmud
Published: May 2023

Sistem jaringan sensor nirkabel membutuhkan frekuensi dengan biaya yang cukup mahal, sirkuit elektromagnetik yang kompleks untuk membuat dua antena daya yang sama output dengan sinyal daya yang sama pula, dan bahan yang murah, terutama untuk komponen elektromagnetik. Antena mikrostrip patch Array Double Sequare 2,4 GHz dengan Single Output yang memiliki daya yang sama menggunakan pembagi daya untuk sensor nirkabel doppler telah diusulkan pada peneilitian ini. antena mikrostrip berbentuk konfigurasi terbaru dengan frekuensi free, konfigurasi lebih sederhana, dan bahan murah pada 2,4 GHz untuk sensor nirkabel doppler pada Sensor Human Vital Nirkabel. Sistem ini merupakan komponen penting dari sensor nirkabel doppler untuk Sensor Human Vital Nirkabel yaitu konfigurasinya terdiri dari antena 2,4 GHz dengan Array Double Sequare dan penggabung daya yang merupakan input ganda dengan output tunggal dengan daya yang sama. Antena memiliki bandwidth sempit dengan frekuensi 2.35-2.47 GHz dengan return loss di bawah -15 dB  dan resonansi frekuensi 2.4 GHz, pola radiasi directional dan gainnya 4.98 dB, Penggabung daya memiliki port S parameter 3 di bawah -20dB di 2.4 GHz dan isolasi di atas -4dB itu semua memiliki nilai yang baik berdasarkan teoritis dan implementasi yang baik. Ukuran keseluruhan dari sistem antena yang diusulkan adalah panjang: 158.2 mm dan lebar: 155,7 mm.dengan Phenolic White Paper - FR4 dengan konstanta dielektrik adalah 4,4. Kata kunci: Antena Mikrostrip, Sensor Nirkabel, Array Double Sequare
ANALISIS KAPASITAS EMBUNG PENIWEN UNTUK SUPLESI AIR IRIGASI
Authors: Iswoyo Budi , Kesy Garside Annisa
Published: May 2023

Kabupaten Malang merupakan daerah agraris memiliki jumlah penduduk 2.544.315 jiwa yang sebagian besar tinggal di perdesaan dengan mata pencaharian bertani,  maka dibutuhkan ketersediaan air utamanya untuk irigasi. Terjadinya perubahan iklim, air menjadi berkurang dan banyak sumber air yang mati pada musim kemarau. Sebagai solusinya perlu dibangun embung. Tujuan penelitian ini untuk mengetahui  kelayakan pembangunan embung Peniwen ditinjau dari aspek teknis. Hasil analisis teknis embung Peniwen dengan perhitungan debit andalan Q80% diperoleh debit andalan maksimum pada bulan Maret Periode I sebesar 0,222 m3/detik dan debit andalan minimum pada bulan September Periode I sebesar 0,058 m3/detik. Hasil analisis debit banjir rencana menggunakan perhitungan Hidrograf Satuan Sintetik Nakayasu dengan kala ulang 100 tahun sebesar 46,93 m3/detik. Tipe embung peniwen adalah tipe urugan homogen dengan panjang 123,33 m dengan lebar puncak 6 m dengan tinggi 12 m, elevasi topdam +407,00 m, elevasi crestspillway +404,50 m, volume tampungan total 58.167,24 m3 dan volume tampungan mati 6.134,69 m3. Embung Peniwen dengan kapasitas tampungan efektif 52.032,55 m3 dapat memenuhi kebutuhan air irigasi untuk lahan sawah seluas 75 hektar dengan pola tanam padi-padi-palawija dengan awal masa tanam bulan Januari. Kesimpulannya bahwa pembangunan embung Peniwen layak secara teknis untuk dibangun. Kata kunci: Hujan efektif, Debit Andalan, Debit Banjir Rencana, Neraca Air, Kapasitas Tampungan Embung,
PENCEMARAN DALAM LINGKUNGAN HIDUP
Authors: Rofik M , Mokhtar Ali
Published: May 2023

AbstrakLingkungan adalah kesatuan antara abiotik serta biotik. lingkungan hidup yaitu kesatuan ruang di seluruh benda. Baik makhluk hidup yang termasuk manusia, keadaan sampai perilaku manusia. Secara keseluruhan bisa disimpulkan jika lingkungan hidup merupakan gabungan antara semua makhluk hidup dan juga faktor dan komponen di sekelilingnya. Makhluk hidup yang ada di bumi ini adalah salah satu faktor keberhasilan dari lingkungan hidup. Kegagalan yang disebabkan oleh makhluk hidup antara lain adalah pencemaran. Dampak dari tercemarnya lingkungan hidup adalah rusaknya ekosistem alami serta berkurangnya baku mutu lingkungan tersebut. Pada dasarnya lingkungan tersebut tercemar akibat kegiatan manusia itu sendiri, baik melalui kegiatan industri ataupun kegiatan rumah tangga yang menghasilkan limbah dan sampah. Pada penelitian ini peneliti melakukan study tentang jenis-jenis pencemaran dan dampak pencemaran terhadap lingkungan. Kata kunci: lingkungan, biotik, abiotik, pencemaran
Consenso colombiano de prevención de enfermedad renal crónica en los niños con bajo peso al nacer
Authors: Cárdenas Aguilera Juan Guillermo , Atehortúa Baena Pahola , Baquero Rodríguez Richard , Lombo Ángela María , Castro Gaona Alba Julietha , Solano Suárez José María , Restrepo Ochoa Diego Alveiro
Published: May 2023

Contexto:  el bajo peso al nacer (BPN) es un factor de riesgo para el desarrollo de enfermedad renal crónica (ERC), aumentando su probabilidad de ocurrencia en la vida adulta hasta en 70% y duplicando el riesgo de ERC en edad pediátrica.
Objetivo: generar recomendaciones para la prevención de ERC en niños con BPN, con lo que se busca optimizar las estrategias de nefroprevención y seguimiento en dicha población.
Metodología: se realizó un consenso de expertos mediante el método Delphi modificado a partir de una búsqueda en los tópicos de interés en las fuentes de datos PubMed, Embase y Google Scholar, donde no hubo restricciones en la búsqueda por año, tipo de estudio o idioma.
Resultados:  se formularon recomendaciones estructuradas en cinco estrategias: 1. reconocer los niños con BPN como población en riesgo de ERC; 2. favorecer un adecuado crecimiento en los niños con BPN a través de una nutrición óptima; 3. realizar un diagnóstico oportuno de lesión renal aguda (LRA) en los niños con BPN y estrategias de prevención y protección renal; 4. evaluación de la función renal en el periodo posnatal inmediato y 5. evaluación de la función renal durante los primeros dos años de vida y su seguimiento posterior.
Conclusiones: las recomendaciones propuestas permitirán definir oportunamente el riesgo de ERC en pacientes con bajo peso al nacimiento, facilitando la intervención temprana con medidas de nefroprevención y seguimiento de esta enfermedad.
A Discussion on the Therapeutic Importance of Medicinal Herbs and Benefits of Proteins Incorporated in XanthPro by Renatus
Authors: Dutta Rajdeep Dutta Gopal , Kar Gautam , Shukla Surya Prakash
Published: May 2023

Protein is one of the building blocks of bone, muscle, and skin. The body needs it to produce hormones, enzymes, and other chemicals. Eating protein-rich foods and taking supplements may help people feel fuller for longer. Feeling full tends to result in smaller portion sizes and less frequent snacking, which can help a person maintain a healthy weight. Due to a hectic lifestyle and poor eating habits, many of us may be lacking the required protein in our everyday diet. Renatus XanthPro is a unique protein supplement formulated with highly essential Vitamins & Minerals to give your body a fulfilling nutritional boost. The primary ingredient of this protein powder is Mangosteen (Garcinia mangostana)- a rich source of one of the rarest and most beneficial antioxidant families known as Xanthones. Xanthones have a broad spectrum of therapeutic properties such as- anti-oxidant, anti-tumor, anti-allergic, anti-inflammatory, anti-bacterial, anti-fungal and anti-viral activities. It is a low-fat composition that helps in weight management. It also contains prebiotic fibre and probiotics that enhance digestion and aid in faster absorption. It protects the body from free radical damage while boosting the energy levels and recovery. It also helps to maintain a healthy blood sugar level and increase the count of white Blood Cells (WBCs) in the blood. It is enriched with immunity-enhancing herbs that make it a better choice for complete wellness. These herbs are of ancient origin and are researched till date to extract more valuable properties in order to enhance human well-being. This review addresses the therapeutic importance of five such medicinal herbs which are an important composition of Xanthpro Protein powder. The inscribed herbs are Licorice (Glycyrrhiza glabra), Ashwagandha (Withania somnifera), Shatavari (Asparagus racemosus), Aloe-Vera (Aloe barbadensis miller) and Gotu Kola (Centella asiatica). Pharmacological experiments have demonstrated that different extracts and pure compounds from these species exhibit a broad range of biological properties. Therefore, the use of these herbal supplements in XanthPro, makes the protein powder to be used more reliably and widely. Overall, it gives our body nourishment as well as protection. It is not just a protein supplement, but is a volutionary step towards a healthy nation.
Keywords: Protein, Renatus XanthPro, Mangosteen, Xanthones, Therapeutic, Immunity-enhancing herbs, Pharmacological, Soy Protein Isolate, Pea Protein Isolate.
Menelisik Kualitas dan Pemahaman Hadis tentang Faktor yang Mendorong Rasulullah SAW Menikahi Aisyah
Authors: Fitria Riri , Ilyas Erizal
Published: May 2023

The marriage practice of Prophet Muhammad (SAW) with Aisha RA has generated various perspectives among Islamic law experts. Starting from Aisha RA's young age, which is considered too young, and the figure of Prophet Muhammad who is made as a role model by Muslims. This research will attempt to find the quality as well as the understanding of hadiths about the factors that led to the marriage. This is important to refute some views that claim that Prophet Muhammad deliberately married an underage child and even took away Aisha RA's childhood. Likewise, the view that Prophet Muhammad tended to marry underage girls. The method used to study the quality of related hadiths is the method of Takhrij Al-Hadith. This is because the hadith that explains this was narrated by Imam Ahmad bin Hanbal, whose authenticity cannot be confirmed yet. As for finding the understanding of hadith scholars about the hadith, the method of understanding the hadith is used so that the comprehension can be known comprehensively. Of the two hadiths that tell about the factors of Aisha RA's marriage to Prophet Muhammad, it was found to be of high quality (shahih), so it can be concluded that the marriage was driven by the command of revelation and the initiative of his companion named Khawlah. This finding refutes the biased view of some people regarding the marriage of Prophet Muhammad with a young girl and even "labeling" him as a pedophile. ABSTRAKPraktik pernikahan Rasulullah SAW dengan Aisyah RA melahirkan berbagai sudut pandang di kalangan pakar hukum Islam. Dimulai dari umur Aisyah ra yang dianggap masih terlalu kecil serta sosok Rasulullah yang dijadikan panutan oleh umat Islam. Penelitian ini akan berusaha mencari kualitas sekaligus pemahaman hadis tentang faktor yang mendorong terjadinya pernikahan tersebut. Hal ini penting untuk membantah beberapa pandangan yang mengatakan bahwa Rasulullah telah sengaja menikahi anak di bawah umur bahkan merampas masa kanak-kanak Aisyah ra. Begitu pula pandangan bahwa Rasulullah cenderung menikah dengan gadis di bawah umur. Metode yang digunakan untuk meneliti kualitas hadis terkait adalah dengan metode Takhrij Al-Hadits. Hal ini dikarenakan bahwa hadis yang menerangkan hal tersebut diriwayatkan oleh Imam Ahmad bin Hambal yang belum bisa diyakini ke-shahih-annya. Adapun untuk menemukan pemahaman ulama hadis terhadap hadis tersebut digunakan metode pemahaman hadis sehingga dapat diketahui pemahamannya secara komprehensif. Dari 2 hadis yang menceritakan tentang faktor pernikahan ‘Aisyah ra dengan Rasulullah ditemukan berkualitas shahih, sehingga dapat disimpulkan bahwa pernikahan tersebut didorong oleh perintah wahyu serta inisiatif dari sahabat beliau yang bernama Khawlah. Temuan ini membantah pandangan miring sebagian masyarakat terkait pernikahan Rasulullah dengan gadis kecil bahkan men”cap” beliau dengan phedouphil.