bluuebunny/crossref_metadata_2025 huggingface dataset:
An Intelligent Location-Based Virtual Indoor Positioning and Navigation Using GPS and Smartphone Sensors
Authors: Patil Samruddhi , Prajapati Roshan , Ratnani Nooren , Shaikh Dr. Mohammed Ahmed
Published: April 2022

Abstract: Various solutions have been suggested for indoor navigation systems in which most methods require the support of external physical hardware infrastructure which increases the complexity and cost of set-up of supporting hardware requirements, which will always be an issue with such systems. In this paper, we present the design of a smartphone based indoor navigation system. The proposed method is supported by a web based architecture, for easily creating indoor maps and providing an indoor location’s information for navigation and positioning. The system has been implemented and the results indicate that the approach is useful for navigation in indoor environments. Terms: Indoor Positioning, Map Generation, Indoor Navigation.
Car Pooling Sustem
Authors: Sree Karuna , Tajammul Dr. Mohammed
Published: April 2022

Abstract: Car pooling System is an automated system which reduces the misery of travelers and makes them find cars in short period of time. Car pooling is an application of finding car in which drivers who are traveling to work alone can ask for fellow passengers through our application. For those who use public-transport system to go to work daily can use this application to find drivers who are traveling to the same destination in a short path. It provides with a simple riding platform between the car owner and car user. This project enables users to access mobility assets own by others exactly when they need. It shows a medium for available cars to pick up them on the interest of car owner with time and capacity. This project aims at creation of a Car-pooling System. Keywords: carpooling, environment friendly
Calculation of Torque and Development of Smart Agri Scarecrow
Authors: Mehar Dr. P. G. , Diwate Sagar , Surjuse Himanshu , Kanher Prathmesh , Kumar Krishna , Siriya Aniket , Chaitguru Parag
Published: April 2022

Abstract: A Smart scarecrow is used to scare the birds and to the animals to store the crop withinside the fields. A farmer positioned the clever scarecrow withinside the center of the world to store plenty of his crop from the birds and animals. We have visible that clever scarecrow has no motion while the birds are to be had field. A clever scarecrow is a decoy or mannequin, frequently withinside the form of a human. Humanoid scarecrows are normally carrying antique garments and located in open fields to deter birds from worrying and feeding on lately forged seed and developing plants. Scarecrows are used throughout the planet via way of means of farmers, and are a extraordinary image of farms and consequently the geographical region in famous culture. The not unusualplace shape of a clever scarecrow is a humanoid determine wearing antique garments and located in open fields to deter birds along with crows or sparrows from worrying and feeding on lately forged seed and developing plants. Machinery like windmills are employed as scarecrows, but the effectiveness lessens as animals grow to be conversant withinside the structures. Farming contributes a first-rate earnings to the Malaysian economy. It is an huge difficulty to farmers as soon as they're a long way farfar from their plants and exposing it to plants’ chance like crow unfavourable the plants and theft. Farming has contributed to almost as much as 22% of a country’s. Keywords: Sensor, Solar Panel, Buzzer, 360º Wi-Fi Camera.
Formulation and Evaluation of Antifungal Cream from Acorus Calamus Linn and Hyptis Suaveolence Poit Oil
Authors: Mishra Rishabh , Jakhmola Vikash , Bhatt S. P.
Published: April 2022

Abstract: Plan: The aim of current investigation to develop a novel cream formulation from essential oil of Acorus calamus and Hyptis suaveolence for the treatment of skin infection. Preface: The delivery of pharmaceutical products through topical route is widely accepted for skin infection. So the development of topical formulation are designed to produced a systematic effect and benifical for the account of several advantages over other route of drug administration. Methodology: Cream formulation consisting essential oil of Acorus calamus (Vach) and Hyptis suaveolence (Vilayati tulsi) was prepared and the formulation was subjected, microbial studies and In- vitro diffusion studies of formulation. Result: The developed cream from essential oil was found to be safe and effective in skin infection Keyword: Acorus calamus, Hyptis suaveolence, Cream formulation.
Application of Polymer and Biomaterials for 3d Printing Technology: Review
Authors: Patel Dhruvin , Shah Rushil , Dalwadi Het
Published: April 2022

Abstract: Polymer and biomaterial 3D printing is an innovative technology that can construct any 3D entity by depositing material layer by layer with current research interpreting towards enlarged use in the medical sector. The different materials like concrete, ceramic, metals, and polymers are usually used for 3D printing. With the purpose of making 3D printing sustainable, scholars are working on the use of diverse bio-derived materials for 3D printing. Polymer and biomaterial printing is beneficial in the medical sector because it empowers the 3D printing of affordable functional parts with good properties and proficiencies. In this review, we highlight current research developments for biomaterial and polymer printing using Fused Deposition Modeling (FDM) for the medical sector. Explicitly, the composition, characteristics, and properties of bio-polymers are discussed. Further, the application of bio-polymers in the medical sector like dental implants, drug delivery systems, and safety equipment and polymers containing bio-fillers are discussed too. Keywords: Polymer, Bio-material, 3D printing, Dental implants, Safety equipment
A Literature Survey on Voice Assistance
Authors: Chowdary A N Bhoomika , M Lavanya , S Darshan , Andani Deepthi , BSK Mrs. Jayasudha
Published: April 2022

Abstract: Artificial Intelligence has been in great use when it comes to day to day life. Computer science defines AI research as the study of brilliant agents. In almost any direction one turns today, some form of computer-based information processing technology intrudes, whether to the individual knowingly or not. Artificial Intelligence (AI) has already changed our lifestyle. AI device that perceives its environment and takes actions that maximize its chance of successfully achieving its goals. Input to recommendation algorithm can be a database of user and items and output recklessly will be the recommendations. The user is the input into system by voice or text. This paper presents a new approach for smart search. Overall, in world there are many people who use assistant. The paper presents applications of virtual assistant and also describes provocation of applying virtual assistant technology. Keywords: Voice Assistance, Python, AI, Review, Text to Speech, Speech to Text, Voice Recognition.
Automated Analysis of Endoscopic Images
Authors: Bhalerao Ashwini , Kale Dipti , Hadke Saylee , Banmare Piyush , Awachat Ritik , Tembhare Prof. Mr. Punesh
Published: April 2022

Abstract: Wireless capsule endoscopy is an important and ongoing diagnostic procedure. It brings a lot of images throughout the journey to the patient's digestive tract and often requires automatic analysis. One of the most notable abnormalities in bleeding and spontaneous isolation of hemorrhage is an interesting research topic. We have developed a computer-based framework that utilizes the latest advances in artificial intelligence based on in-depth reading comprehension to successfully support the entire screening process from video transmission to automatic wound detection to reporting. More precisely, our method of handling multiple video uploads at the same time, automatically scans them for the purpose of identifying important video frames with potential lesions (subsequent analysis by endoscopies) and brings doctors to the methods of linking detected and previously detected lesions. or with current photographs and scientific information from relevant documents to obtain a more accurate final conclusion. Auto DL is considered useful for the site development of advanced read-through learning models. An untested endoscopic with a certain level of expertise can at least benefit from AutoDL support. Keywords: convolutional neural network, deep learning, automated deep learning, endoscopy, gastric neoplasms, neural network, deep learning model, artificial intelligence
CONCEPT AND TYPES OF COPYRIGHT VIOLATIONS IN THE INFORMATION AND DIGITAL SPACE
Authors:   Южно-Российский институт управления – филиал Российской академии народного хозяйства и государственной службы при Президенте РФ, Ростов-на-Дону, Россия, Диана Владимировна Горенко
Published: April 2022

The article analyzes the concept of copyright infringement in the digital information space. It proposes its own definition of the category "civil offense" in order to consolidate it in the Civil Code of the Russian Federation. The features of the composition of copyright infringement in relation to the information-digital space are highlighted. A classification of copyright infringements is proposed. In order to reduce copyright infringements in the digital information space, it is necessary to provide at the legislative level a system of optional registration of copyright by introducing a deposit procedure into civil legislation.
JUDICIAL DISCRETION IN CRIMINAL PROCEEDINGS: THE CONCEPT, ESSENCE AND POSSIBILITIES OF RESTRICTION
Authors:   Южно-Российский институт управления – филиал Российской академии народного хозяйства и государственной службы при Президенте РФ, Ростов-на-Дону, Россия, Сергей Анатольевич Алтухов ,   Ростовский институт (филиал) Всероссийского государственного университета юстиции, Ростов-на-Дону, Россия, Андрей Викторович Любимов ,   Ростовский институт (филиал) Всероссийского государственного университета юстиции, Ростов-на-Дону, Россия
Published: April 2022

The article considers the legislative mechanisms of the institution of judicial discretion in the consideration of criminal cases. Based on the analysis of theoretical and legal grounds and judicial practice, the permissible limits are determined, excluding the possibility of an arbitrary approach of the court when deciding on the imposition of penalties in criminal cases, as well as problems of legal and other nature of judicial discretion that affect the quality of Russian justice, and ways to eliminate them are proposed.
REGULATORY AND LEGAL REGULATION IN THE FIELD OF PHYSICAL CULTURE AND SPORTS
Authors:   Южно-Российский институт управления – филиал Российской академии народного хозяйства и государственной службы при Президенте РФ, Ростов-на-Дону, Россия, Елена Сергеевна Айвазова , Олег Иванович Селиванов ,   Ростовский филиал Российской таможенной академии Ростов-на-Дону, Россия, Елена Николаевна Дорофеева ,   Южно-Российский институт управления – филиал Российской академии народного хозяйства и государственной службы при Президенте РФ, Ростов-на-Дону, Россия
Published: April 2022

The article is devoted to modern problems of regulatory regulation in the field of physical culture and sports. Russia is a social and legal state that recognizes the rights and freedoms of its citizens. The highest goal of such a state is to carry out such a social policy that will ensure a decent life and harmonious development of the individual. At the same time, rights in all spheres of life should be guaranteed and the field of physical education and sports should not be an exception. And the legal regulation of relations in this specific area should be the most transparent, complete and clear.
THE POWER OF THE STATE AS A CIVILIZATIONAL DOMINANT IN RUSSIA: TO THE RESOURCES OF METHODOLOGICAL PLURALISM
Authors:   Московский городской педагогический университет, Москва, Россия, Елена Михайловна Крупеня
Published: April 2022

The article is devoted to the study of the power of the state - the dominant actor in the institutional complex of the Russian local civilization. In a conceptual way, the research program is substantiated, constructed on the basis of the principle of methodological pluralism, synthesis of achievements of general legal theory and other areas of socio-humanitarian knowledge. Taking into account the achievements of the civilizational approach to the typology of state and law, the author actualizes the socio-psychological assessments of state power as the dominant subject of public law in Russia.
ACTUAL PROBLEMS OF THE FIGHT AGAINST CORRUPTION IN THE THE CURRENT STAGE OF DEVELOPMENT
Authors:   Южно-Российский институт управления – филиал Российской академии народного хозяйства и государственной службы при Президенте РФ, Ростов-на-Дону, Россия, Святослав Петрович Федоренко ,   Ростовский юридический институт МВД России, Ростов-на-Дону, Россия, Людмила Александровна Бураева ,   Северо-Кавказский институт повышения квалификации (филиал) Краснодарского университета МВД России, Нальчик, Россия
Published: April 2022

The article deals with the actual problems of the fight against modern corruption. It is indicated which aspects of digitalization have led to corruption activities. The prospects of combating corruption-related crimes in the context of the development of digital technologies are evaluated. The key problems of the modern Russian state and society in overcoming and minimizing corruption manifestations are indicated.
IMPROVEMENT OF THE CONSTITUTIONAL FOUNDATIONS OF NATIONAL UNITY OF RUSSIAN SOCIETY
Authors:   Южно-Российский институт управления – филиал Российской академии народного хозяйства и государственной службы при Президенте РФ, Ростов-на-Дону, Россия, Павел Петрович Баранов
Published: April 2022

The article analyzes the idea of single civil nation in the context of the problem of ensuring the national unity of Russian society. The author examines general theoretical approaches to understanding this problem and its reflection at the level of constitutional and legal policy of the state. The author concludes that today in Russia there are no clear and scientifically substantiated mechanisms for solving the problem of national unity of Russian society due to the fact that individual components of the relevant problematic are transferred from the category of “accompanying” to “main”, which leads to the leveling of the central problem. The article also draws attention to the entire block of social problems that complicate the implementation of the idea of national unity.
ELECTORAL JUSTICE OF THE EASTERN REPUBLIC OF COLOMBIA
Authors:   АНО «Центр прикладных исследований и программ», Москва, Россия, Алексей Валерьевич Шидловский ,   Бюро по демократическим институтам и правам человека ОБСЕ, Ростов-на-Дону, Россия
Published: April 2022

The realization of citizens' electoral rights and their effective protection provided by electoral justice bodies are the basis of democracy. The meaning of electoral justice is an impartial and independent approach to disputes arising on the implementation of citizens' electoral rights from other state bodies. The democratic system of Colombia is one of the oldest in Latin America, but it is far from the most perfect in terms of the organization of the electoral justice system. That is why one of the key elements of moving towards strengthening Colombian democracy is the existence of electoral justice bodies with sufficient capacity, transparency and impartiality to ensure the legality of electoral processes. In this article, the author analyzes the modern Colombian approach to electoral justice, discusses the main shortcomings of the Colombian electoral justice bodies, as well as the reasons that give rise to such shortcomings, and concludes that in Colombia, control over the electoral process and the subsequent implementation of citizens' electoral rights are not effective, given the actual presence of electoral justice bodies in the country. The reasons for this situation are different and lie both in certain features of the socio-historical development of the region, and in the imperfection of the norms of the current legislation. In the conditions of a high degree of distrust of citizens to the electoral process in particular and to democracy in the country as a whole, the only solution to the problem is the development of mechanisms that exclude the interference of parties, as well as legislative and executive bodies in the elections of senior officials of these entities. Meanwhile, the institution of electoral justice itself objectively shows its effectiveness and is recommended for implementation in the Russian Federation in the form of an autonomous system of electoral courts, including the Federal Electoral Court, Electoral Courts of the constituent entities of the Federation, Municipal Electoral Courts and Electoral judges corps of polling stations.
THE PECULIARITY OF THE LEGAL NATURE OF INTERNATIONAL DEBT LAW
Authors:   Южный федеральный университет, Ростов-на-Дону, Россия, Лариса Ивановна Волова
Published: April 2022

In this article, the author examines important problematic issues of international debt law as an institution of international financial law: he determines the trends of development now and in the future of international legal norms, rules, standards. Leadership in the field under consideration. The article provides an assessment of acceptable ways to solve the debt problem at the universal level. The author suggests ways to more effectively restructure the external debts of states, taking into account their legislation and contractual practice. The evaluation of documents related to the management of external debts of States is given.
UNFAIR TERMS IN THE DOCTRINE THEIR MANIFESTATION IN LICENSE AGREEMENTS
Authors:   Южный федеральный университет, Ростов-на-Дону, Россия, Даниил Аркадьевич Корецкий
Published: April 2022

The article examines the criteria of unfair terms in the civil law of the Russian Federation and the specifics of their manifestation in license agreements. The conducted research has shown that the common markers of unfair terms are a clear burden on one of the parties and a violation of the balance of interests. There are also specific manifestations, such as excessive liability, excessive price, the possibility of unilateral refusal on unfavorable terms, etc. From the analysis of domestic and foreign literature and practice, it follows that unfair terms in license agreements take almost the same forms as in contracts from Part II of the Civil Code of the Russian Federation. However, there is a specificity due to a specific result of intellectual activity.
PHYTOPLANKTON BIODIVERSITY AND POLLUTION BIOINDICATOR IN BOJONEGARA COASTAL WATERS, BANTEN BAY, INDONESIA
Authors: Sulistiono Sulistiono , Ronauli Eva Cristine , Pertiwi Niken Tunjung Murti , Effendi Hefni
Published: April 2022

Coastal waters of Bojonegara in Banten Bay has a lot of pressure from the surrounding environment, including industry and sand mining. The high intensity and limited space encourage reclamation in coastal areas which can trigger changes in water quality. Research was conducted from October to December 2019, aims to analyze the phytoplankton biodiversity and pollution bioindicator of the waters. The phytoplankton was obtained through filtering 50 liters of water at a depth of 30 cm or surface waters. Observations were also made on water quality conditions including transparency, depth, color, temperature, pH, salinity, and dissolved oxygen (in-situ) and turbidity, Total Suspended Solid (TSS), nitrate, nitrite, and total phosphate (ex-situ). Data analysis was performed on abundance, diversity index, eveness and dominance, similarity index, and saprobic index. Based on observations, it is known that the phytoplankton found were in the class Bacillariophyceae, Chlorophyceae, Cyanophyceae, Dinophyceae, and Chrysophyceae. The index values of diversity, eveness, and dominance of phytoplankton each ranged from 0.2223-1.0070; 0,1289-0,5664; and 0.1550-0.8181, respectively. According to these values, the Bojonegara waters were classifeied as mild to moderate ecological pressure. The similar conditions are also indicated by the saprobic index values. The result of Main Component Analysis (PCA) shows the first component with 53.726% variance represented by turbidity parameters, TSS, total phosphate, transparency, depth, temperature, pH, and DO. These parameters have the most influence on the presence of phytoplankton.
PEMANFAATAN KOMPOS AMPAS TEBU PADA TANAMAN SORGUM (Shorgum bicolor (L.) Moench) DI LAHAN KERING : OPTIMALISASI PEMANFAATAN LAHAN KERING DI PROVINSI JAMBI
Authors: Soverda Nerty , Evita Evita
Published: April 2022

Sorghum is one type of cereal plant that has great potential to be developed in Indonesia because it has a wide adaptation area. Sorghum has been known and cultivated for a long time in several regions in Indonesia. The opportunity to increase production through increasing productivity is still very large because up to now the productivity that has been achieved is only 60% of the potential yield of each new variety that has a potential yield of 6 tons / ha. One of the causes of low sorghum production is due to minimum fertilization and nutrient-poor soil. Efforts that can be made to keep crop production balanced will require innovation in the supply of environmentally friendly plant nutrients, one of which is by utilizing bagasse waste into organic fertilizer. The study was conducted at the Experimental Garden of the Faculty of Agriculture, Jambi University, Mendalo Indah Village, Jambi Luar Kota District, Muaro Jambi Regency which was located at an altitude of 35 m above sea level and Ultisol soil type. The study aimed to determine the effect of bagasse compost on the growth and yield of sorghum and to obtain a dose of bagasse compost that can provide the best growth and yield of sorghum. This study was conducted using a randomized block design (RBD) with one factor, namely the dose of organic bagasse organic fertilizer consisting of 4 levels of treatment. The treatment used in this study was (P0) administration of inorganic fertilizers, (P1) administration of 5 tons / ha bagasse organic fertilizer, (P2) giving 10 tons / ha bagasse organic fertilizer, (P3) giving bagasse organic fertilizer 15 ton / ha. The variables observed were plant height, number of leaves, age of flowering, root dry weight, plant dry weight, panicle length, seed weight per plant, weight of 1000 seeds, and yield per hectare. The results showed that bagasse compost treatment had a significant effect on plant height. However, there was no significant effect on the number of leaves, age of flowering, root dry weight, dry weight of plants, panicle length, weight of 1000 seeds and dry seed weight of planting and harvest index
Exact solutions of Effective-Mass Schrödinger Equations on Quantum Kerr- (A) Ds Galilean Myers– Perr driven gravitational transformations for the anti-COVID-19 RoccuffirnaTM drug design.
Authors: Grigoriadis Ioannis
Published: April 2022

General methods to quantize combined descriptors of both the probability
and phase/current distributions in molecular electronic reference frame
transformations, to a “superposition of coordinate transformations”
have been previously introduced. Continuity equations for these
densities are explored on an array of recent fundamental observations
developed through gravitational amplification of primeval density
fluctuations generated in the exceedingly early phase of cosmic
evolution. In this paper, I show that the notion of vertical-equilibrium
state of the vanishing current entanglement in chemical space and
orbital superpositions are observer-dependent features in quantum
reference frames including Galilean transformation, and near-horizon
symmetries ranging from supergravity theories to Lorentzian
cryptographic signatures to enhance the RoccuffirnaTM’s gravity to trap
the SARS-COV-2 viruses in practice. The corresponding stationary radial
Schrödinger equations with these potential energy functions are solved
analytically, in the underlying information continuity equation that
determines machine learning characteristics for both Euclidean and
Lorentzian signatures to Quantum microBlackHole-Inspired Kerr- (A)
dS-Myers–Perry black Gravitationals in an approximate scheme for zero
total angular momentum. It is found that the wave functions for bound
states can be expressed in terms of the Jacoby polynomial involving
either the nonclassical or resultant entropy/information concepts the so
called horizontal-equilibrium state, which represents the
phase-transformed quantum state of a molecule, corresponding to the
optimum, density-dependent “thermodynamic” phase in the near-horizon
limit, with either SL(2, ℝ) or Poincaré iso(1, 1) symmetry which extends
to the entire near-horizon geometry . This analytical expressions for
purely vibrational energy levels of the electronic state, without an
accompanying change of quantum observables, preserves the electron
probability distribution but modifies its current by varying the moduli
to a weakly-coupled description of a pharmacophoric system, where states
with fixed conserved charges can be counted. The influence of the
equilibrium-phase gravitational transformation, quantum phase density,
and local entropy formalism production is examined on the continuity
chemical relations for the anti-COVID-19 RoccuffirnaTM molecular
equilibrium states.
MODELLING AND SIMULATION OF THE KINEMATIC BEHAVIOUR OF THE DEPLOYMENT MECHANISM OF SOLAR ARRAY FOR A 1-U CUBESAT
Authors: Muhammed Lawal Nasir , Iyenagbe Ugheoke Benjamin , Nwachukwu Dorin
Published: April 2022

Cubesats have transcended mere demonstration systems to sophisticated
missions which invariably require the use of deployable solar arrays for
more power generation. The kinematics of deployment have considerable
influence on the stability and attitude control of a satellite,
especially one with such low mass as Cubesats. This work aimed to model
and simulate two-wing deployable solar array, with a sun tracking tilt
function for a 1-U CubeSat, with emphasis on the deployment mechanism
using materials locally available in the country. The design is such
that four panels attached to two wings hinged at Y and – Y directions
deploy slowly and smoothly at approximately 2 seconds where the
vibration decays exponentially and approaches zero. The model of all
parts, as well as the computational analysis were done with SOLIDWORKS
software. The system was tested for vibration and stability using the
seismic mass-spring-and-damper arrangement and the Bond Graph technique
was used to conduct kinematic analysis of the mechanism. A 3-D printing
was generated and tested to evaluate its operational performance. The
simulated results of the model were validated with the prototype outputs
with an error of 0.03% in energy supply reliability, about 400% more
power generated than the body mounted solar panels of same satellite
specification without a significant impact on system strength and
Stability.
Assessment of Honey production and Marketing System in Jimma Horro District, Kellem Wollega Zone, Western Oromia Ethiopia
Authors: Kuma Tolera , Abdisa Soresa Shuma
Published: April 2022

This Survey was conducted in Jimma Horro (Ethiopia) to assess honey
production and marketing systems in three farm hand associations were
nominated by means of purposive selection systems. From each PA, 48
beekeepers (a total of 144) were deliberately nominated and questioned
by pre-tested, organized forms. Outcomes of the study presented that the
mean honey yield per year/colony was 7.4, 11.25, and 20.6kg for
traditional, transitional and moveable frame hives, respectively. Honey
marketing contributors were producers, collectors, retailers and
consumers. There was no variance in price of crude honey between study
locations (P>0.05) and no significance difference
(P>0.05) were observed. Honey yield per hive/year was found
to be low from traditional and transitional hives as compared to
moveable frame hive. Thus, strong extension and practical involvement is
critical for agriculturalists to use the moveable frame hives and
revenue of beekeepers within the study area. This study suggested as
more emphasis should incline to the bee product diversification and
processing and marketing system for the sake of the higher benefit.
A transcriptional complex of FtMYB102 and FtbHLH4 coordinately regulates the accumulation of rutin in Fagopyrum tataricum
Authors: Zhang Dong , Mi Yaolei , Li Yu , Qian Guangtao , Vanhaelewyn Lucas , Meng Xiangxiao , Liu Tingxia , Yang Wei , Shi Yuhua , Ma Pengda , Atia-tul-Wahab * , Chen Shilin , Sun Wei
Published: April 2022

Tartary buckwheat ( Fagopyrum tataricum) is rich in flavonoids,
which not only play an important role in plant-environment interaction,
but are also beneficial to human health. Rutin is a therapeutic flavonol
which is massively accumulated in Tartary buckwheat. It has been
demonstrated that transcription factors (TFs) control rutin
biosynthesis. However, the transcriptional regulatory network of rutin
is not fully clear. In this study, through transcriptome and target
metabolomics profiling analysis together with homolog prediction, we
identified and validated the role of FtMYB102 and FtbHLH4 TFs at the
different developmental stages of Tartary buckwheat. The elevated
accumulation of rutin in the sprout appears to be closely associated
with the expression of FtMYB102 and FtHLH4. Yeast two-hybrid, transient
luciferase activity and co-immunoprecipitation analysis demonstrated
that FtMYB102 and FtbHLH4 can interact and form a transcriptional
complex. Moreover, yeast one-hybrid showed that both FtMYB102 and
FtbHLH4 directly bind to the promoter of chalcone isomerase (
CHI), and they can coordinately induce CHI expression as
shown by transient luciferase activity assay. Finally, we transferred
the FtMYB102 and FtbHLH4 into the hairy roots of Tartary buckwheat and
found that they both can promote the accumulation of rutin. Our results
indicate that FtMYB102 and FtbHLH4 can form a transcriptional complex by
inducing CHI expression to coordinately promote the accumulation
of rutin.
Characterization and microsatellite marker development for a common bark and ambrosia beetle associate, Geosmithia obscura
Authors: Pietsch Grace , Klingeman William , Huff Matthew , Kolarik Miroslav , Hadziabdic Denita , Gazis Romina , Staton Margaret (Meg)
Published: April 2022

Background. Symbioses between Geosmithia fungi and wood-boring and bark
beetles seldom result in disease induction within the plant host. Yet
exceptions exist such as Geosmithia morbida, the causal agent of
Thousand Cankers Disease (TCD) of walnuts and wingnuts, and Geosmithia
sp. 41, the causal agent of Foamy Bark Canker disease of oaks. Isolates
of G. obscura were recovered from black walnut trees in eastern
Tennessee and at least one isolate induced cankers following artificial
inoculation. Due to the putative pathogenicity and lack of recovery of
G. obscura from natural lesions, a molecular diagnostic screening tool
was developed using microsatellite markers mined from the G. obscura
genome. Results. A total of 3,256 candidate microsatellite markers were
identified (2236, 789, 137 di-, tri-, and tetra- motifs were identified,
respectively), with 2011, 703, 101 di-, tri-, and tetra- motifs
containing markers with primers. From these, 75 microsatellite markers
were randomly selected, screened, and optimized, resulting in 28
polymorphic markers that yielded single, consistently recovered bands
which were used in downstream analyses. Five of these microsatellite
markers were found to be specific to G. obscura and did not
cross-amplify into other, closely related species. Although the
remaining tested markers could be useful, they cross-amplified within
different Geosmithia species, making them not reliable for G. obscura
detection. Conclusion. Five novel microsatellite markers (GOBS9, GOBS10,
GOBS41, GOBS43, GOBS50) were developed based on the G. obscura genome.
These species-specific microsatellite markers are available as a tool
for use in molecular diagnostics and can assist future surveillance
studies.
Associations between late-onset preeclampsia and the use of calcium-based antacids and proton pump inhibitors during pregnancy: a prospective cohort study
Authors: Gelder Marleen van , Beekers Pim , Rijt-Weetink Yrea van , Drongelen Joris van , Roeleveld Nel , Smits Luc
Published: April 2022

Objective: To determine associations of calcium-based antacid and PPI
use during pregnancy with late-onset preeclampsia (≥34 weeks of
gestation), taking into account dosage and timing of use. Design:
Prospective cohort study. Setting: This study used data from the PRIDE
Study (2012-2019) and Dutch Pregnancy Drug Register (2014-2019). Sample:
A total of 9,058 pregnant Dutch women aged ≥18 years. Methods: Data were
collected through web-based questionnaires and obstetric records. We
estimated risk ratios (RRs) for late-onset preeclampsia for any use and
trajectories of calcium-based antacid and PPI use before gestational day
238, and hazard ratios for time-varying exposures after gestational day
237. Main outcome measure: Late-onset preeclampsia. Results: Late-onset
preeclampsia was diagnosed in 2.6% of pregnancies. Any use of
calcium-based antacids (RR 1.2 [95% CI 0.9-1.6]) or PPIs (RR 1.4
[95% CI 0.8-2.4]) before gestational day 238 was not associated
with late-onset preeclampsia. Use of low-dose calcium-based antacids in
gestational weeks 0-16 (<1g/day; RR 1.8 [95% CI 1.1-2.9])
and any use of PPIs in gestational weeks 17-33 (RR 1.6 [95% CI
1.0-2.8]) seemed to increase risks of late-onset preeclampsia. We did
not observe associations between late-onset preeclampsia and use of
calcium-based antacids and PPIs after gestational day 237. Conclusions:
In this prospective cohort study, use of calcium-based antacids and PPIs
during pregnancy was not found to reduce the risk of late-onset
preeclampsia. Funding: Netherlands Organisation for Health Research and
Development [ZonMw; grant number 848018010].
Clinical outcomes of conventional HDR intracavitary brachytherapy combined with complementary applicator-guided intensity modulated radiotherapy boost in patients with bulky cervical tumor
Authors: Lu Shun , Wang Shubin , Kim Robert Y , Zhang Jiayu , Wang Xianliang , Wang Weidong , Zhu Guiquan , Zhou Jie , Tan Yan , Tan Mingyu , Li Minglun , Yin Gang , Li Jie , Feng Mei , Lang Jinyi
Published: April 2022

Objective To investigate the clinical outcomes and toxicity in patients
with locally advanced cervical cancer treated with supplementary
applicator guided-intensity modulated radiation therapy (IMRT) based on
conventional intracavitary brachytherapy (IC/IMRT). Population Large
high risk clinical target volume (HR-CTV) volume (>40cc) at
the time of brachytherapy cervical cancer patients were recruited.
Methods This study is a retrospective analysis of 76 patients with
locally advanced cervical cancer (FIGO IIB-IVA) treated with concurrent
chemo-radiotherapy followed by IC/IMRT between June 2010 and October
2016. External radiotherapy (45 Gy in 25 fractions) with cisplatin
chemotherapy treated before IC/IMRT. The prescription dose for HR-CTV
and IR-CTV were 6 Gy and 5 Gy per fraction for 5 fractions respectively.
Results: Mean HR-CTV was 65.8±23.6 cc at the time of brachytherapy. D90
for HR-CTV and IR-CTV were 88.7±3.6 Gy and 78.1±2.5 Gy. D2cc for
bladder, rectum, sigmoid and small intestine were 71.8±3.8 Gy, 64.6±4.9
Gy, 63.9±5.3 Gy and 56.7±8.7 Gy respectively. Median follow-up was 85
months (47.9-124.2 months). Five-year local recurrence free survival
rate, metastasis recurrence free survival rate, disease free survival
rate and cancer special survival rate were 87.6%, 82.4%, 70.9% and
76.3%, respectively. The grade 1+2 gastrointestinal and urinary late
toxicities were 15.8% and 21.1%, while grade 3 late toxicities were
3.9% and 5.2%, respectively. Neither acute nor late grade 4
gastrointestinal or urinary toxicities were seen. Conclusions: The
combination of ICBT with an applicator-guided supplementary IMRT boost
achieved an excellent local control and overall survival with low
toxicity for bulky residual cervical tumor
Injury trends among foreign and domestic tourists in Jeju from 2008 to 2018
Authors: Hwang Ki Sang , Lee Sung Kgun , Song Sung Wook , Kim Woo Jeong , Kang Young Joon , Kang Kyeong Won , Park Hyun Soo , Park Chang Bae , Kang Jeong Ho , Bu Ji Hwan , Ko Seo Young
Published: April 2022

Jeju is the largest island in Korea and one of its key tourist attractions. As the number of foreign tourists steadily increases, so does the number of injuries incurred there. Accordingly, this study aimed to describe and compare the characteristics of injuries suffered by foreign tourists versus those of domestic tourists. As a cross-sectional study of a retrospective medical record survey, the study was conducted with reference to the Jeju Injury Surveillance System from the 11-year period of January 2008 to December 2018. The following factors were investigated: demographic data, mechanism of injury, place of occurrence, activity when injured, patient outcome, and mortality. A total of 92,095 injured Jeju Island visitors was recorded during this time, a number that included 88,050 Koreans and 4,045 foreigners. The gender ratio showed similar patterns between the two groups and there were no significant age differences. In both groups, the most common mechanism of injury was collisions/cuts. Also, more foreigners experienced falls than Koreans. Regarding the location, Koreans had the most road accidents, while foreigners were most likely to be injured at outdoor locations, such as seas and rivers. Furthermore, more foreigners experienced severe injuries requiring hospitalization. Notably, this study showed the differences in injury between foreign and Korean tourists visiting Jeju Island and its findings lend support to targeted safety promotion programs.
Stem anatomical survey of the genera Matricaria and Tripleurospermum (Asteraceae) from Turkey with its taxonomical and ecological implications
Authors: Ozcan Melahat , Inceer Huseyin
Published: April 2022

A comparative anatomical study of the stems in 32 taxa assigned in the two
related genera; Matricaria (4 taxa) and Tripleurospermum (28 taxa, 30
accessions), was carried out in Turkey by using cluster analysis (CA) and
principal component analysis (PCA) to address generic classification and
taxa delimitation. All the studied taxa have the following stem
characteristics: one layer of epidermal cells with a sparse distribution of
non-glandular trichomes, a cortex composed of interchanging collenchyma and
chlorenchyma cells, a number of schizogenous secretory ducts near the
bundles, ovate to oblong and open collateral vascular bundles which are
arranged in a ring and are variable in size, and parenchymatous pith. The
differences among the taxa are mainly the thickness of the xylem in the
vascular bundle, the length of the epidermal cells and the pith cell size.
The taxonomic and ecological values of the anatomical data are discussed in
light of the current framework.
Toimintakulttuurin avoimuuden linjaus
Authors: Avoimen tieteen ja tutkimuksen koordinaatio
Published: April 2022

Toimintakulttuurin avoimuuden linjaus kokoaa yhteen kansallisen avoimen tieteen ja tutkimuksen koordinaation piirissä tehtyjen aikaisempien linjausten ja suositusten näkökulmia siten, että huomio on organisaation toimintakulttuurin avoimuudessa. Lisäksi aiempia linjauksia täydennetään palveluihin, kannustimiin ja vuorovaikutukseen liittyvillä näkökulmilla.
Development and implementation of a national online application system for cross-jurisdictional linked data
Authors: Wray Natalie , Miller Kate , Irvine Katie , Moore Elizabeth , Crisp Alice , Baupaume Kathleen , Taylor Catherine , Smetak Rob , Wiggins Nadine , Dombrovskaya Mikhalina , Flack Felicity
Published: April 2022

The Population Health Research Network (PHRN) is an Australian national data linkage infrastructure that links a wide range of health and human services data in privacy-preserving ways. The data linkage infrastructure enables researchers to apply for access to routinely collected, linked, administrative data from the six states and two territories which make up the Commonwealth of Australia, as well as data collected by the Australian Government. The PHRN is a distributed network where data is collected and managed at the respective jurisdictional and/or cross-jurisdictional levels. As a result, access to linked data from multiple jurisdictions requires complex approval processes. This paper describes Australia's approach to enabling access to linked data from multiple jurisdictions. It covers the identification of, and agreement to, a minimum set of data items to be included in a unified national application form, the development and implementation of a national online application system and the harmonisation of business processes for cross-jurisdictional research projects. Utilisation of the online application system and the ongoing challenges of data linkage across jurisdictions are discussed. Changes to the data custodian and ethics committee approval criteria were out of scope for this project.
Atrial Fibrillation in a Patient with Interatrial Block after Successful Atrial Flutter Ablation: May Interatrial Block Be a Link for a Continuum of Atrial Arrhythmias?
Authors: Antonopoulos, MD, PhD, FESC Athanassios , Donigaglia, MD Daniele , Amadei, MD Gian Andrea
Published: April 2022

Background: Electrocardiographic interatrial block (IAB) typically exists when a conduction delay over the Bachmann’s bundle is present. By analogy to other types of block, there is a continuum of IAB severity; partial IAB is defined as a P-wave duration 120 ms and advanced interatrial block (aIAB) is defined as a P-wave duration 120 ms in conjunction with biphasic P-wave morphology in inferior leads II, III, and aVF. Moreover, IAB seems to be a key factor in the genesis of atrial fibrillation (AF). On the contrary, it is not clear if the presence of advanced IAB may be associated with an occurrence of AF after cavotricuspid atrial flutter ablation in patients without previous episodes of atrial fibrillation.
So, may be useful to evaluate on surface electrocardiogram the P-wave morphology and duration in sinus rhythm after the ablation procedure just to identify patients at high risk for atrial fibrillation development. Advanced IAB is frequently associated with atrial tachyarrhythmias, and it was found to predict AF and may be helpful for clinical decisions.
Case presentation: In this case involving a man who underwent a typical atrial flutter ablation, we documented that aIAB during the post-ablation period which seems to induce atial fibrillation episodes. To our knowledge, it is unusual to detect an aIAB after cavotricuspid atrial flutter ablation and subsequently associate it with a new onset of AF.
Conclusions: Our observation supports a possible aIAB induction of AF after cavotricuspid atrial flutter ablation and potentially may representing a link in the continuum of atrial arrhythmias. P-wave morphology and duration should be better evaluated soon after AFlu ablation to better stratify patients who are at high risk for atrial fibrillation development and eventually prolonged anti-coagulation therapy.
Dakwah Melalui Media Sosial (Studi Netnografi Konten Ruqyah Syar’iyah pada Akun Tiktok Ustadz @eriabdulrohim)
Authors: Mutia Tika , Taufiqurrahman Muhammad Ilham , Handoko Tito
Published: April 2022

Eri Abdulrohim merupakan seorang da’i yang juga merupakan seorang trainer, konsultan yang populer dengan dakwah melalui media sosial Tiktok. Ia dikenal sebagai Ustadz yang rajin mengunggah konten berkenaan dengan pengobatan melalui Ruqyah Syar’iyah. Tujuan penelitian ini adalah untuk menganalisis bagaimana penggunaan media sosial khususnya pada konten Ruqyah Syar’iyah di Tiktok sebagai sarana dakwah Ustadz Eri Abdulrohim. Penelitian ini merupakan penelitian kualitatif dengan menggunakan metode Netnografi yang menitikberatkan pengamatan pada subjek penelitian di media sosial Tiktok. Objek penelitian adalah konten yang berupa video bertema Ruqyah Syari’iyah pada akun Tiktok @eriabdulrohim. Hasil penelitian menunjukkan bahwa dari seluruh konten video dakwah Ustadz Eri Abdulrohim di Tiktok sejak 2021, terdapat 3 Video yang tinggi jumlah viewersnya dan viral karena mengangkat tema Ruqyah Syar’iyah. Unggahan konten yang paling diminati netizen berisi terapi ayat Alqur’an untuk penyembuhan dari sihir. Selain itu, konten dakwah di Tiktok ustadz Eri memberikan kontribusi baru karena dikemas singkat, sesuai fenomena terkini, dan sesuai dengan syariat Islam.
Dakwah, Identitas Lokal, dan Media Sosial: Spirit Pemuda Hijrah Baubau
Authors: Hidayatullah Zait , Ardiansyah Ardiansyah
Published: April 2022

Berangkat dari fenomena gerakan dakwah anak muda yang sangat mengemuka di Indonesia pada beberapa tahun belakangan ini, tulisan ini mengkaji tentang salah satu gerakan dakwah anak muda di Baubau, Sulawesi Tenggara. Kajian sebelumnya yang mengkaji gerakan dakwah anak muda sebagian besar terfokus pada gerakan dakwah anak muda di perkotaan. Oleh karena itu, tulisan ini memfokuskan kajiannya pada gerakan dakwah anak muda di ruang lingkup lokal. Dengan memfokuskan studi kasus pada gerakan dakwah anak muda di tingkat lokal, tulisan ini menemukan perbedaan-perbedaan terhadap cara mereka mengemas dakwahnya, terutama ketika berhadapan dengan identitas lokal. Berdasarkan hasil wawancara dan etnografi online, tulisan ini menemukan bahwa Spirit Pemuda Hijrah Baubau mengemas gerakan mereka dengan identitas lokal seperti bahasa wolio dan simbol bangunan budaya lokal. Meskipun demikian, program dakwah mereka tetap dipengaruhi oleh gerakan-gerakan dakwah anak muda di perkotaan yang lebih mapan, serta menggunakan produk globalisasi seperti media sosial.
Menghafal Al Quran Bagi Anak Didik Sekolah Dasar Islam Terpadu Insan Cendikia Bangkinang: Perspektif Manajemen Dakwah
Authors: Sitorus Siti Hazar , Yasir Al
Published: April 2022

Al-Qur’an adalah kitab suci umat Islam yang dengan membacanya sudah mendapatkan pahala apalagi menghafal dan mengamalkannya. Penelitian ini menjelaskan tentang bagaimana upaya Sekolah Dasar Islam Terpadu (SDIT) Insan Cendekia Bangkinang dalam mengajarkan dan menanamkan pemahaman penghafalan Al-Qur’an kepada anak didiknya dilihat dari tinjuan manajemen dakwah. Penelitian ini menggunakan metode penelitian kualitatif dengan model studi lapangan (field research) kemudian dideskripsikan secara naratif untuk memberikan kemudahan kepada pembaca dalam memahami naskah penelitian. Hasil penelitian menunjukkan bahwa manajemen yang dilakukan dalam proses menghafal Al-Qur’an adalah dengan melakukan perencanaan pada tahap awal peserta didik memulai proses menghafal; Pelaksanaan yaitu dengan menggunakan metode yang dilakukan oleh pihak SDIT yaitu gabungan metode sima’i, jama’, dan talqin; Pengarahan adalah cara yang dilakukan untuk mengarahkan peserta didik dalam proses menghafal. Dengan metode gabungan ini dan evaluasi yang dilakukan pada akhir semester genap, dapat diketahui kemampuan peserta didik dan pengukuran target yang telah ditentukan. Melalui proses manajemen serta metode yang baik, SDIT mampu memenuhi target peserta didik memiliki hafalan sebanyak tiga juz yaitu juz 28, 29, dan 30 saat tamat nanti.