bluuebunny/crossref_metadata_2025 huggingface dataset:
Correlation of the Need for Orthodontic Treatment between the self-perception of Chilean adolescents aged 14 to 18 years and the dentist’s diagnosis
Authors:   Facultad de Odontología. Universidad de La Frontera, Temuco, Chile. CIDIC Research Center, Facultad de Odontología. Universidad de La Frontera, Temuco, Chile., Acevedo-Atala Claudia , Montiel-Company José María ,   Departamento de Estomatología, Facultad de Odontología y Medicina. Universidad de Valencia, España, Atala-Acevedo Claudia ,   Facultad de Odontología. Universidad de La Frontera, Temuco, Chile., Corsini-Muñoz Gilda ,   Facultad de Odontología. Universidad de La Frontera, Temuco, Chile. CIDIC Research Center, Facultad de Odontología. Universidad de La Frontera, Temuco, Chile, Beltrán-Varas Víctor ,   Facultad de Odontología. Universidad de La Frontera, Temuco, Chile. CIDIC Research Center, Facultad de Odontología. Universidad de La Frontera, Temuco, Chile., Jans-Muñoz Alejandra ,   Facultad de Odontología. Universidad de La Frontera, Temuco, Chile. CIDIC Research Center, Facultad de Odontología. Universidad de La Frontera, Temuco, Chile.
Published: May 2021

Background: To correlate the need for orthodontic treatment between the self-perception of Chilean adolescents from 14 to 18 years old with the observation of a dentist using the same assessment scale, as well as to determine if covariates such as gender, age and type of school influence the self-perception of the adolescent and the examiner. Material and Methods: Cross-sectional descriptive study of adolescents aged 14 to 18 years from public, subsidized and private schools in Temuco, Chile. The probability sample is stratified by course, from first to fourth year, a total of 414 students participated, according to the eligibility criteria. The photographic score of the aesthetic component (AC) of the Index of Orthodontic Treatment Need (IOTN) was used. The statistical analysis of the data was performed with the SPSS Statistics program v.23. Results: 94.9% of the adolescents perceived themselves as having good aesthetics. The examiner considered that 77% presented this condition, p<0.00. Males perceived themselves better than females. At age 15, 1.7% of students considered themselves to have poor aesthetics, p<0.01. From the examiner's perspective, aesthetics are related to type of school, p<0.00. Conclusion: Adolescents perceive themselves better aesthetically than do the evaluators. The school type factor, according to the IOTN-AC examiner, shows a higher proportion of students with no need for orthodontic treatment in private schools, and a threshold need in municipal and subsidized institutions.
Oral health behaviour perception scale applied among a sample of Portuguese adolescents.
Authors:   CI&DETS – Polytechnic Institute of Viseu, Portugal., Amaral Odete , Couto Patrícia ,   Universidade Católica Portuguesa, Faculty of Dental Medicine, Centre for Interdisciplinary Research in Health (CIIS), Portugal., Coelho Inês ,   Family Health Unit Grão Vasco, Viseu, Portugal., Correia Maria José ,   Universidade Católica Portuguesa, Faculty of Dental Medicine, Centre for Interdisciplinary Research in Health (CIIS), Portugal., Veiga Nélio Jorge ,   Universidade Católica Portuguesa, Faculty of Dental Medicine, Centre for Interdisciplinary Research in Health (CIIS), Portugal.
Published: May 2021

Introduction: The application of a scale can be particularly useful for the epidemiological studies comparing different populations and for analysis of the influence of distinct aspects of oral health on the development of certain health conditions. The aim of this study consists in the creation of a scale to classify the level of perception of the oral health behaviors applicable to a sample of Portuguese adolescents. Material and Methods: An observational cross-sectional study was designed with a total of 649 adolescents between the ages of 12 and 18 years old from five public schools in the Viseu and Guarda districts, in Portugal. Data was collected by the application of a self-administered questionnaire and, after analysis of data collection, the newly Universidade Católica Portuguesa (UCP) oral health perception scale was created. Statistical analysis was performed using SPSS-IBM software version 24.0 (IBM SPSS, Chicago, Il., USA). In the descriptive statistical analysis, absolute and descriptive frequencies were used for variables with nominal measurement level, mean as a measure of central tendency and standard deviation as a measure of dispersion for interval variables. Results: Oral health behaviors perception respecting the assumptions defined by the present scale has been elaborated. The result showed that 67% of the sample presented a poor perception of their oral health behaviors, 23.9% intermediate/sufficient, while 8.2% refer having good perception, respecting the assumptions defined for the elaboration of the present scale. Conclusion: For this purpose, through the scale to classify the level of oral health behaviors applicable to the sample of portuguese adolescents, it is possible to compare the data of several samples and understand what are the most frequent oral or eating habits among adolescents.
Rómer, az ősrégész
Authors: Bóna István
Published: May 2021

Rómer, az ősrégész
Edelmetallmünzen Konstantin des Grossen
Authors: R. Alföldi Mária
Published: May 2021

Edelmetallmünzen Konstantin des Grossen
Régészet és történelem
Authors: László Gyula
Published: May 2021

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Adalékok Pannonia történetéhez és topográfiájához
Authors: Mócsy András
Published: May 2021

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A langobárd-szláv-avar együttélés egyik régészeti bizonyítékáról
Authors: Bóna István
Published: May 2021

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Tompa Ferenc emlékének
Authors: Banner János
Published: May 2021

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Die mittelalterliche Siedlungsgeschichte des Bodrogköz
Authors: Valter Ilona
Published: May 2021

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Die keltisch-römische Siedlung von Tác
Authors: Kocztur Éva
Published: May 2021

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Pannonische Stempelziegel I. Limes-Strecke Annamatia-Ad Statuas
Authors: Lőrincz Barnabás
Published: May 2021

X
Urban problems in the civil town of Aquincum: the so-called „northern band”
Authors: Láng Orsolya
Published: May 2021

Abstract of PhD thesis submitted in 2013 to the Archaeology Doctoral Programme, Doctoral School of History, Eötvös Loránd University, Budapest under the supervision of Dénes Gabler.
A belső vámok szerepe a rajnai és a dunai provinciák importált kerámiaspektrumában
Authors: Gabler Dénes
Published: May 2021

The political, strategical and cultural blocks in the Roman Empire functioned as economic units as well. The European provinces can be divided in two major groups: the Gaulish – Germanian provinces and the ones in the Danube valley. The economic development of these two areas differed significantly not only at certain points in time, but diverged all through the centuries of the Imperial period. The establishment of customs districts and the organisation of their administrative network played an important role in forming these economic units. Experience has provided evidence that the distribution of certain goods transported too far from their production areas can be recorded by the borders between customs districts. It can be contemplated that the markets may have been divided to facilitate the quick and efficient supply of the two main armies in Europe: namely in the Rhine region and in Illyricum. This supply could have been made possible by the clear distinction between shipments. A certain duality is apparent both in the spectrum of imported pottery and sources concerning the problem of which customs district Raetia belonged to? Some features in the composition of types within the imported material (Italian terra sigillata of the Tiberian – Claudian period, Sarius-ware, glazed Italian pottery, lamps, Raetian pottery) indicate strong economic ties with the Danubian provinces. Other ware however, reveals differences between the two areas (terra sigillata tardo-padana, thin-walled pottery, amphorae, terra sigillata produced in Westerndorf or Pfaffenhofen). This contradiction should perhaps be explained by suggesting the change in customs borders by annexion of the province. That is, a customs district may be regarded as an economic unit and as such must be taken into consideration, when the distribution of several interprovincial types of finds is discussed.
Topographical research in the canabae of Brigetio in 2014
Authors: Bartus Dávid , Borhy László , Czajlik Zoltán , Holl Balázs , Puszta Sándor , Rupnik László
Published: May 2021

The present article introduces a recently started project which aims at studying the topography of the canabae and legionary fortress of Brigetio using non-destructive methods such as aerial photography and different geophysical surveys. After a brief summary of earlier research, the methods and results of the topographical work carried out in 2014 will be discussed below.
Aerial Geoarchaeological Survey in the Valleys of the Mureş and Arieş Rivers (2009-2013)
Authors: Czajlik Zoltán , Berencki Sándor , Rupnik László
Published: May 2021

The paper presents the most important results of the Romanian–Hungarian aerial archaeological project, i.e.the intensive topographic research of the Middle Mureş Valley. Situated between the mountains, in the widen-ing valley section various aged/high terraces were formed, providing proper conditions for human habitats.Beside the already documented stone buildings from the Roman period, observed due to the negative cropmarks – especially in 2013 – positive crop marks of settlements datable before and after the Roman periodwere observed in large variety. The simultaneous examination of the geomorphological conditions underlinedsignificant differences between the prehistoric and Roman strategies of settlement establishment.
A 15th–16th century cannon foundry workshop in Buda. Craftsmen and technology of cannon moulding and the transformation of military technology from the Renaissance to the Post Medieval Period
Authors: Belényesy Károly
Published: May 2021

Abstract of PhD thesis submitted in 2014 to the Archaeology Doctoral Programme, DoctoralSchool of History, Eötvös Loránd University, Budapest under the supervision of András Kubinyi and István Feld.
Short report on the excavations in Brigetio in 2015
Authors: Bartus Dávid , Borhy László , Számadó Emese
Published: May 2021

In 2015, first time in the history of excavations in Brigetio, the Department of Classical and Roman Archaeology of Eötvös Loránd University and the Klapka György Museum of Komárom carried out excavations in all three major parts of Brigetio: the civil town, the canabae and the legionary fortress.At the site Szőny-Vásártér, the excavation was concentrated on a Roman cellar with collapsed wooden ceiling and a large pit nearby. Most important results are the complete excavation of the cellar, where a large amount of pottery vessels, a Dressel 20 amphora and a bronze cavalry parade helmet came to light. In the territory of the canabae (Szőny-Dunapart) two horrea and another stone building with uncertain function have been found. At the legionary fortress (Szőny-MOL-Kiskertek), the fieldwork was concentrated on the principia and its surroundings.
New results of the excavations at the Saint James’ Pauline friary and at the Castle Čabraď
Authors: Mordovin Maxim
Published: May 2021

In 2015 the Department of Hungarian Medieval and Early Modern Archaeology of Eötvös Loránd University participated inexcavations at five different sites, including Pauline friary at Bakonyszentjakab, castles at Fiľakovo (Fülek), Zvolen(Zólyom) and Čabraď (Csábrág) in Slovakia, Franciscan friary in Szécsény and a post medieval château at Sângeorgiu deMureş (Marosszentgyörgy) in Romania. This report presents the two major from the aforementioned projects.
Cemetery of the late Tumulus – early Urnfield period at Balatonfűzfő, Hungary
Authors: Ilon Gábor
Published: May 2021

On the outskirts of Balatonfűzfő, an excavation was carried out by Sylvia K. Palágyi between 1991–1994 as a continuation of the excavation in 1966 that preceded the construction of the so-called Delta junction of roads no. 71–72. In 1992–1993, during the excavation of a Roman Age pottery workshop five graves of a late Tumulus – early Urnfield period (Br D2–Ha A1) cemetery came to light. Each cremation grave (with the cremated remains either scattered in the pit or put in an urn) was characterised by a certain burial rite. The richest grave (no. 6) was that of an adult male, buried with his weapons, among them a uniquely decorated knife with a grip terminating in a bird's head. Graves no. 2 and no. 4 contained female burials with jewellery, while grave no. 1 belonged to a child, and included jewellery as well as several ceramic vessels.
Recording well and craniotomy for electrophysiology in head-restrained mice v1
Authors: Chen Susu , Svoboda Karel
Published: May 2021

Recording well and craniotomy for acute extracellular electrophysiological recordings in head-restrained mice
Adsorption-Extraction for SARS-CoV-2 RNA Detection and Quantification in Wastewater using RT-ddPCR v1
Authors: Bivins Aaron , Ahmed Warish , Bibby Kyle
Published: May 2021

The following protocol describes the GERM Lab workflow for processing wastewater for SARS-CoV-2 electronegative membrane filtration (with MCE membrane), extraction, and interrogation by reverse transcription droplet digital PCR (RT-ddPCR). It is synonymous to method B as described in Ahmed et al. 2020 (referenced) with modifications to the consumables and PCR format. It is intended for use in a BSL2+ lab with extra precautions for processing environmental specimens for SARS-CoV-2 as described in the CDC Interim Laboratory Biosafety Guidelines.
Fear to Retaliation: The Most Frequent Reason for Not Helping Victims of Gender Violence
Authors: Melgar Patricia , Geis-Carreras Gemma , Flecha Ramon , Soler Marta
Published: May 2021

When faced with situations of gender-based violence, one becomes exposed to risk in giving support to the victim (van Reemst, Fischer, & WC Zwirs, 2015, Hamby, Weber, Grych, & Banyard, 2016; Liebst, Heinskou & Ejbye-Ernst, 2018). This form of violence, second order of sexual harassment (SOSH), occurs when people who support victims of gender-based violence experience violence themselves because of this positioning (Vidu et al., 2017; Flecha, 2021). There is little research on the subject. Through a quantitative study carried out with 1541 Spaniards over 18 years of age, we provide, for the first time, quantitative evidence of the incidence of SOSH in the responses of people who have been aware of a situation of gender-based violence. Our results show that SOSH is an important obstacle; 40% of people who did not offer help in the case of gender-based violence did not do so for reasons that correspond to SOSH.We concluded that the fear of suffering SOSH can condition people’s reactions in the environment, thereby limiting the possibility of female victims of violence receiving help.
ETHNIC UKRAINIAN CUISINE AS AN ELEMENT GASTORONOMIC TOURISM IN UKRAINE
Authors: Pushka Olga , Sharan Larisa , Arpul Oksana , Sharan Andrey
Published: May 2021

Goal. The purpose of the article is to substantiate the expediency of studying the ancient culture of the Ukrainian people, in particular, acquaintance with the customs and recipes of the ethnographic region in the framework of gastronomic tours throughout Ukraine. After all, statistics show that holding such events inspires young people to study the culture of their ancestors.

Method. The methodological basis of this work are the works of domestic and foreign scientists in the field of hospitality, scientific periodicals, Internet resources. The methodology includes generalizing and statistical data, which reflect the feasibility of gastronomic tourism in Ukraine.

Results. As a result of the research, the national and world experience in teaching young people about cultural values, traditions, local national cuisine by combining recreation and gastronomic tours throughout Ukraine and abroad was analyzed. It was proved the expediency of expanding such national events with the revival of ancient recipes of national dishes of each area and the desire of Ukrainians to maintain and learn about their culture. It is noted that each ethno-region of Ukraine is famous for its local dish: dumplings, brynza, riplyanka, etc., but Ukrainian borscht according to the ancient recipe can be eaten in almost every corner of Kherson and Chernihiv, Poltava, Ivano-Frankivsk, Cherkasy, Lviv, Zhytomyr, Sumy, Vinnytsia, Dnipropetrovsk.

Scientific novelty.

Scientific novelty. The expediency of introduction and expansion of holidays and festivals as an element of gastronomic tourism development is determined. Domestic and world experience in combining travel and learning about national traditions of local cuisine in the form of gastronomic festivals is systematized. It is proved that most of such measures are concentrated in Central and Western Ukraine, as indicated by the obtained statistical facts.

Practical significance. The materials presented in the paper can be used to improve the regional tourism policy, in particular, for the initiation and expediency of local gastronomic tours and festivals in each region of Ukraine. The launch and holding of gastronomic festivals not only has a positive effect on the image of the territory, but also opens up opportunities for additional impetus to the development of territories and its cultural values.
An Algorithm for Covering the Vertices of a Directed Graph
Authors: Knyazyatov M.O. , Rasskazova V.A.
Published: May 2021

The article presents an algorithm for solving the applied problem of assigning and moving locomotives, based on the solution of the graph–theoretic problem of covering the vertices of a directed graph with a set of oriented paths. A detailed example is given for an algorithm for covering the vertices of a directed graph with a set of maximal paths.
On Different Approaches to Solving Extreme Problems
Authors: Kulanin Y.D. , Nurkaeva I.M. , Stepanov M.E.
Published: May 2021

The article discusses the geometric and analytical methods for solving known extreme problems and identifies the logical relationships between these problems, the preference for using one or another method for solving extreme problems is shown by specific examples.
An Analysis of Sangam Tamil Society’s Ethical Framework as Instructed in Puṟanāṉūṟu
Authors: Et. al. Dr Manjula M,
Published: May 2021

Puṟanāṉūṟu is a historical document that serves as a record of the rich cultural heritage of the ancient Tamil civilization. It is filled with ethical guidelines that will serve as guidelines to live by till the end of human civilization. Seventeen poems in Puṟanāṉūṟu are considered a part of the Poruṇmoḻikkāñci section. This essay will analyse the ethical guidelines given to rulers on how to rule and to citizens on how to be good citizens.
The seismic waves from the Port Chicago explosion*
Authors: Byerly Perry
Published: May 2021

The records of the Port Chicago explosion alone suggest the conclusion that an averaged layering for California is 3 km. of rock of speed 5.0 km/sec. for longitudinal waves overlying a layer 11 km. thick of speed 5.6 km/sec., which in turn overlies a medium of speed 7.7 km/sec. No waves which traversed the mantle were observed. The root of the southern Sierra Nevada blocks the 7.7 km/sec. were even as it blocks the 8.0 km/sec. P normal waves.

The air wave seems definitely recorded at Berkeley and Santa Clara as wave of period 3 or 4 seconds. The differential speed between the stations was normal, 342 m/sec. There is a suggestion of a short-period (0.5 sec.) air wave at Stanford with over-all speed of 333 m/sec.

From study of the seismograms it is concluded that the energy in the earth waves was about 1016 ergs, or roughly of the order of one-thousandth of the probable energy released in the explosion.
Differential-motion seismographs*
Authors: Omer Guy C.
Published: May 2021

summary

A group of nonpendular seismographs actuated by the phase differences at two points in the earth's crust are analyzed for their transient and their steady-state behavior. The seismographs considered are the Benioff Linear Strain seismograph, the transversely driven rod seismograph suggested by Benioff, terminated rod seismographs of a new type, and a seismograph utilizing optical interference.
Triggered telerecording seismic equipment*
Authors: Gane P. G. , Logie H. J. , Stephen J. H.
Published: May 2021

Electronic equipment is described which has been designed for research into the Witwatersrand earth tremors. It enables six seismograms (originating at different sites up to 17 km. away) to be recorded side by side on a common time scale. High-speed recording is obtained by automatically triggering the (usually stationary) recorder, while the signals are “stored” for six seconds on a magnetic tape delay unit so that no part of the record is missed. Automatic magnification control is used at the transmitting end, and a method of frequency-modulating a subcarrier, appropriate for transmitting very low-frequency signals, is described. Some seismograms obtained by this means are shown.
Vibrations in multiple-story structures from earthquakes*
Authors: Stevens P. E.
Published: May 2021

This paper offers a relatively simple analysis by means of which the motions in the several stories of a building, resulting from harmonic vibration of its foundation, may be theoretically determined. The method is correct. The accuracy of the results depends only upon the reliability of the data available.
Desarrollo de un sistema de gestión energética en la clínica Portoazul
Authors: Botero Ebrat Sebastian Andrés
Published: May 2021

En este trabajo se desarrolla un sistema de gestión energética, basado norma ISO 50001, para la Clínica Portoazul, ubicada en la primera zona franca de salud de la Costa Atlántica. Durante el estudio se identificó la electricidad como el principal portador energético consumido en la clínica. Adicionalmente, se identificaron los equipos y/o sistemas con mayor demanda eléctrica. Basado en las diferentes mediciones y datos de consumo eléctrico de la clínica, se desarrolló una línea base y un indicador de desempeño garantizando una correlación R2 > 60%. El indicador de desempeño se utilizó como base para desarrollar el sistema de gestión energética. Los resultados de implementación del sistema de gestión entre enero y febrero de 2020 muestran una reducción del consumo de electricidad diario entre un 1 y un 15% respecto a la línea base.
The Impact of Machine Learning on the Future of Insurance Industry
Authors: Paruchuri Harish
Published: May 2021

Recently data remains the central and the core concentration in the insurance industry. The outburst in data generation thus created the need for technologies that will be used to process or manage big data in the industry. Thus, the conditions at hand are sighted by a plodding but firm change, which is compelled by an atmosphere shown by enhanced rivalry, fraud activities, flexible market places, high prospects from clients, and stringent guidelines. The introduction of machine learning in solving industry tasks in the assurance value chain such as underwriting and forfeiture avoidance, entitlements management, fraud uncovering, product evaluating, transactions, and client capability will put the industry in the damp light in the future due to high increase of big data. This paper has examines some cases and bring out the vital role of machine learning in handling client data and resolving issues of entitlements. Hence, machine learning holds a brighter future for insurance organizations if implemented well.
Teaching Medical Ethics and Professionalism to Undergraduate Medical Students in an Innovative Way
Authors: Bandyopadhyay Ujjwal , Bandyopadhyay Ranjana , Mudey Abhay
Published: May 2021

BACKGROUND Medical education curriculum in India focuses on the clinical skills of the medical students as cornerstone, but patient and patient party dealings and to work as a member of health care provider team, one requires communication skills, interpersonal skills, management skills, professionalism and ethics. Teaching learning methods (TLM) for imparting module of professionalism and ethics have to be innovative and nonconventional also. In the present study, we tend to assess the effectiveness of exposure to realistic clinical scenarios in pathology department, in teaching medical ethics and professionalism, to undergraduate medical students. METHODS This is an experimental, interventional study that included 200 students. All have attended “just-in-time” lectures on attitude, communication, professionalism and ethics (AETCOM) delivered by faculties. After the 15 days of lecture session, all the students were assessed about their skill of AETCOM by conducting objective structured practical examination (OSPE). In the next phase exposure to realistic clinical scenarios in the Departmental laboratory of Pathology, under the guidance of faculties was also arranged. After the exposure session to real life scenario, all the students were assessed about their skill of AETCOM again by conducting OSPE and their performance was compared with the previous OSPE score. Feedback from the exposed students was also taken in prescribed proforma of 7-point Likert scale. RESULTS Mean pre exposure OSPE score was 18.66 and mean post exposure OSPE score was 27.22. The result shows that the difference was significant (P < 0.001). 38.5 % students were extremely satisfied with the experience of exposure to real life situation in pathology lab and 50 % students were very satisfied with the experience of exposure. In the present study, mean learning gain is 77 %. CONCLUSIONS Professionalism and ethics should neither be introduced in isolation from other medical graduation course contents nor be assessed so. It should be coherently assimilated with the current curriculum. KEYWORDS Communication Skills, Interpersonal Skills, Professionalism, Ethics, Teaching Learning Methods (TLM)
A Cross-Sectional Study on Students’ Feedback on the Introduction of Foundation Course in the MBBS Programme in a Government Run Medical College of West Bengal
Authors: Bandyopadhyay Ujjwal , Ghosh Koushik , Saha Rajdeep
Published: May 2021

BACKGROUND Medical students in India come from diverse cultural, linguistic, economic and social backgrounds. Further, students from similar backgrounds are often found to have obtained their school education from different educational boards. Thus, to ensure a smooth initiation of these diverse population of high school graduates to the challenging medical science curriculum, a foundation course at the beginning of Bachelor of Medicine and Bachelor of Surgery (MBBS) programme was considered to be of utmost importance. General guidelines for this ‘Foundation Course’ were laid down and all institutions were expected to abide by them but provisions were allowed to institutions to make local changes depending on the context and requirements. We wanted to analyse the feedback from the students regarding the foundation course. METHODS A pre-validated questionnaire-based, cross-sectional study was carried out among MBBS students in our institution. The study was conducted in the month of November 2019 after obtaining the institutional ethics committee clearance. RESULTS Most of the students agreed (a total of 86 out of 96 students) with the comment that the course fulfilled the objectives set out in the foundation course brochure. 52.08 % students agreed and 29.16 % students strongly agreed that the course satisfied their need and expectations. 88 out of 96 students agreed that there was opportunity for feedback and evaluation which in turn gives the scope to introduce formative assessment in the course. This constituted the best part in our learning experience. CONCLUSIONS In general, majority of the students’ feedback on the foundation course was in an affirmative note. Most of them felt that the course was well structured and informative enough for them to apply the newly learnt lessons to cope with some of their real-life problems. Their positive feedback as well as the relevant suggestions they submitted will obviously contribute towards encouraging the involved faculties as well as the institute to execute the foundation course in a more user-friendly and structured manner in the future years to come. KEYWORDS Foundation Course, Feedback, MBBS
Immunohistochemical Expression of Ki-67 and p53 in Surface Epithelial Ovarian Tumour
Authors: Singh Mahendra , Khan Lubna , Kamthan Ankita
Published: May 2021

BACKGROUND Surface epithelial ovarian tumour (SEOT) develops from the outer surface of ovary. It accounts for more than 90 % of all the ovarian tumours. Most of the SEOT are benign. Few SEOT are of low malignant potential or high malignant potential. The purpose of this study was to assess the rate of expression of proliferative marker Ki-67 and staining pattern of p53 in various histological types of SEOT. METHODS It was a randomised type of study carried out in the Department of Pathology, GSVM Medical College, Kanpur, for 2 years. It included 100 random patients with surgically resected specimens of SEOT. Ki-67 immunohistochemistry (IHC) was performed on all malignant cases and few random benign cases; and the percentage of immunopositive cells in each case was expressed as Ki-67 labelling index (Ki-67 LI). p53 expression was interpreted as positive when cells showed diffuse and intense nuclear staining in malignant cases. RESULTS Out of 100 cases, 70 were benign and 30 were malignant. Cases comprised of serous and mucinous histological subtypes. In all malignant cases, Ki-67 expression was found to be positive (Ki-67 LI > 1 %). Highest Ki-67 LI of 52 % was associated with high grade serous cystadenocarcinoma. High grade serous carcinoma (HGSC) had higher p53 positivity. 88.8 % of HGSC were p53 positive. CONCLUSIONS Ki-67 is a cost-effective proliferative marker; therefore, its assessment can be included in routine histopathological report of SEOT for better understanding of the biologic behaviour and aggressiveness of the tumour. p53 expression was more common in HGSC and can help in discriminating between HGSC and lowgrade serous carcinoma (LGSC). KEYWORDS p53, Ki-67, Ovarian Tumour, Serous, Mucinous, SEOT
Correlation of Fine Needle Aspiration Cytology with Histopathological Findings in the Diagnosis of Thyroid Swellings – A One Year Study in a Tertiary Care Hospital, Hyderabad
Authors: Muppidi Keerthana , Kedarisetti Vidya , Mahankali Kanya Kumari
Published: May 2021

BACKGROUND Most of the thyroid swellings are non-neoplastic and with normal thyroid hormone. So, it doesn't require any surgical excision, even though the thyroid swelling is an indication for surgical excision. The present study was done to evaluate the accuracy of fine needle aspiration cytology (FNAC) for the thyroid swellings and correlate it with the histopathological findings. METHODS This is a prospective study. A total of 47 cases were studied. Fine needle aspiration cytology was done, slides were made and studied. Histopathological examination of the corresponding 47 cases was also done and correlated with FNAC findings. Sensitivity, specificity and accuracy were calculated. RESULTS Age of the patients varied from 20 - 69 yrs. Most of them were in the age group of 30 - 39 years and 50 - 59 years. The ratio of male to female was 1:4.9. Swelling of the neck was the most common presentation in most of the patients. On FNAC 33 (70.2 %) cases were diagnosed as colloid nodular goitre, 04 (8.5 %) as autoimmune thyroiditis, 08 (17.0 %) as follicular neoplasm, 01 (2.1 %) as suspicious of malignancy, 01 (2.1 %) as papillary carcinoma. On histopathological examination 25 (53.2 %) cases were diagnosed as colloid nodular goitre, 01 (2.1 %) as fibrous thyroiditis, 01 (2.1 %) as Graves’ disease, 07 (14.9 %) as Hashimoto’s’ thyroiditis, 06 (12.8 %) as follicular adenoma, 01 (2.1 %) as follicular carcinoma, 04 (8.5 %) as papillary carcinoma and 02 (4.2 %) as NIFTP (noninvasive follicular thyroid neoplasm with papillary like nuclear features). The overall sensitivity was 69.2 %, specificity was 97.0 % and accuracy was 89.3 %. CONCLUSIONS FNAC is a minimally invasive, highly accurate and cost-effective procedure. FNAC helps the clinician to diagnose malignant lesions with confidence. It has high rates of specificity and accuracy but comparatively has less sensitivity. However, it is very important for the management of patients with thyroid swelling. KEYWORDS Fine Needle Aspiration, Prospective Study, Sensitivity, Specificity, Thyroid Swelling
The Incidence and Risk Factors of Retinopathy of Prematurity in Sick Newborn Care Unit in a Tertiary Care Hospital in Eastern India - A Cross-Sectional Observational Study
Authors: Sengupta Pinaki , Kumar Sheuli , Mazumdar Mohua , Majumdar Soumyadeep , Pande Manideepa
Published: May 2021

BACKGROUND Retinopathy of prematurity (ROP) is one of the leading causes of ocular morbidity and mortality throughout the world. Prematurity, low–birth, and oxygen therapy are considered to be the common risk factors. The maldeveloped retina in those affected are very much prone to develop refractive error, neo-vasculopathy, and neurosensory detachment. The purpose of our study was to find out the incidence and ascertain the risk factors of retinopathy of prematurity among the neonates attending the sick neonatal care unit and OPD of Calcutta National Medical College & Hospital. METHODS This is an institution based cross-sectional observational study conducted in the sick newborn care unit of a tertiary care hospital. Informed consent was obtained from the parents along with proper birth history. Indirect ophthalmoscopy with a + 20 dioptre (+ 20 D) lens with a paediatric scleral depressor was performed in each eye under the guidance of the neonatologist after pupillary dilatation. If either eye was found to have ROP, the baby was considered as an ROP case in the study and each eye was considered as a single case. RESULTS 50.27 % babies (N = 91) were delivered by Lower Uterine Segment Caesarean Section (LSCS) and 55. 24 % babies were < 32 weeks of gestational age whereas 21.45 % (N = 39) babies were having < 1500 gm birth weight. Phototherapy was needed in 50 % of the babies (N = 92) whereas hyperbilirubinemia was present in 59.66 % of total babies. Bradycardia, apnoea, and sepsis were present in 29.83 % (N = 54), 25.41 % (N = 46), 41.98 % (N = 76) of the babies respectively. When compared in the two independent groups (ROP present and absent), low gestational age and low birth weight of the babies were found to be statistically significant (P < 0.05) for the development of ROP. After adjusting with different factors in the regression model we have found that low birth weight and oxygen therapy after birth were statistically significant with the development of ROP (P < 0.05). CONCLUSIONS ROP screening, specifically for those babies with low-birthweight, low gestational age, and those who received oxygen therapy for other systemic reasons, is mandatory to have an early diagnosis and treatment done. KEYWORDS ROP, Low-Birthweight, Gestational Age, Oxygen Therapy
Алгоритмическое и информационное обеспечение разработки готовых лекарственных форм (ГЛФ) лекарственных средств в твердой форме
Authors: В.Ф. Корнюшко , Николаева О.М. , Р.Р. Биглов , Колыбанов К.Ю. , Филоретова О.А.
Published: May 2021

The article discusses the problem of creating an algorithmic and informational support for the pharmaceutical development of ready-made medicines (GLF) medicines in solid form. For the system implementation of the algorithms for the development of GLF on the basis of the principle of QbD (quality-by-design - quality planned during development) it is proposed to apply the methodology of system design based on the principle (diagrams) of Demming. The algorithms for modeling and optimizing the selection of the technology platform for the pharmaceutical development of GLF medicines in solid form are given. The block scheme of the developed algorithm of the simulation and optimization process based on multi-tissue regression models and the online algorithm of optimization of Huka-Jeeves is presented. Testing of the developed algorithmic and software on the example of the development of the drug diphenhydramine.
Аналитические модели для решения задачи классификации данных
Authors: Митина О.А.
Published: May 2021

Credit risk management is the main task of banks and other credit institutions. Untimely partial or complete non-repayment of the loan body, as well as the interest part, within the period established by the agreement and in compliance with all the conditions provided for, is one of the main causes of losses of financial institutions. Data mining technologies contain effective tools for building scoring models – neural networks, decision trees, and logistic regression to predict the value of the target variable that allows you to assess the creditworthiness of the client. The purpose of this article is to show the relevance of the problem of data classification on the example of the financial and credit sphere (credit loan).
Элементы хореографии в процессе физического воспитания студентов
Authors: Айвазова Е.С.
Published: May 2021

The article considers the place of choreographic training in the process of physical education of students. The concept of choreography and its elements, as well as methods and techniques of physical education of students by means of choreography are revealed.
Педагогическая физиология доминанты А.А. Ухтомского при функционировании зеркальных нейронов мозга
Authors: Ананьев В.Н , Ананьева О.В. , Семизоров Е.А.
Published: May 2021

Increasing the amount of information in the educational process requires the development of new pedagogical approaches in teaching. Therefore, we propose for use in education a new method in the form of a pedagogical physiological dominant, which combines the use of pedagogical methods based on the physiological mechanisms of the brain. The analysis of A. A. Ukhtomsky's teaching about the dominant showed that mirror neurons function actively only with a pronounced dominant. Mirror neurons and the principle of their work is aimed at achieving a naturally useful result of the activity of the animal and human body, which is determined by the degree of severity of the dominant. The paper shows a new property of dominant formation, which was not studied by Academician A. A. Ukhtomsky, which is that the dominant can be formed or strengthened as a result of the work of mirror neurons
Состояние противопожарной безопасности в кабинете химии центра-колледжа прикладных квалификация Мичуринского государственного аграрного университета
Authors: Балашова Н.А. , Кострикин А.В.
Published: May 2021

The article deals with the organization of fire safety techniques during chemistry lessons on the example of a specific educational institution-the Center-College of Applied Qualifications of the Michurinsky State Agrarian University.
Международная программа обмена как средство изучения языка и культуры Германии
Authors: Вельдина Ю.В.
Published: May 2021

The article deals with the international program as one of the effective teaching methods of learning German. Immersion in the environment of the studied language and communication with native speakers helps not only to improve knowledge in grammar, phonetics, vocabulary, but also to learn more about the culture of the people, their customs, traditions, and history. Also, the international program helps to get rid of stereotypes that hamper intercultural communication and therefore language acquisition.
Принцип интеграции в образовательном процессе дошкольного образовательного учреждения
Authors: Зорикоева Н.В. , Нарыкова Г.В.
Published: May 2021

The education sector is constantly looking for ways to ensure that every child can achieve the necessary level of development for further successful learning at every level of the continuing education system. Special attention is paid to the creation of optimal conditions for the development of preschool children, to the realization of their right to affordable education. The article reveals the essence of the integrated approach to the construction of the educational process in pre-school institutions, actualizes its practice-oriented orientation, shows the components of the content of such an educational process.
Размышления о Первой мировой войне
Authors: Соловьева Е.В. , Костюшин Р.А
Published: May 2021

The article analyzes the reasons for the outbreak of the First World War, its result for our country, the impact of that massacre on the subsequent development of the world, Russia and the current state of mankind.
Психологические аспекты влияния внутрисемейных отношений на формирование личности ребенка
Authors: Агирбова Д.М. , Аджиева Д.Б.
Published: May 2021

The scientific work presents an analysis of the influence of various aspects of intrafamily relationships between parents, as well as parents themselves with children on the formation of the child's personality. It is shown that the harmonious development of the child's personality is possible only under the condition of a favorable atmosphere in the family and the optimization of relations between the parents themselves
Изучение влияния дистанционного обучения на качество сна студентовиностранцев медицинской академии имени С.И. Георгиевского
Authors: Козуля С.В.
Published: May 2021

The purpose of the work was to study the impact of distance learning on the quality of sleep of foreign students. The PSQI questionnaire was used. Result - the quality of sleep of students, studying remotely, we can define it as "good". However, the average PSQI score for students, who are currently studying in Russia, was 19.6% higher than for students, who are joining classes via the internet from India. The division of points by PSQI components also showed that the quality of sleep for students who are in a familiar environment and in more comfortable conditions is naturally better than in their compatriots who are studying in another country. Thus, if the change of full-time training to distance learning is inevitable, for a better rest (and, as a result, for more productive work), it is advisable not to keep the student in the hostel, but encourage their return to his homes. Moreover, a decrease the number of people, living in the hostel, will also help to reduce the spread of infectious diseases (at this point in time – COVID-19).
Использование учебно-исследовательских проектов в естественнонаучном образовании
Authors: Андрианова С.С.
Published: May 2021

The article discusses the issue of how one of the research activities of students as one of the popular forms of educational work of general educational institutions, the important task of which is to prepare a student-researcher who knows modern search methods.
Современные представления о профилактике воспалительных заболеваний пародонта
Authors: Журбенко В.А.
Published: May 2021

Periodontal diseases are one of the most pressing problems of dentistry. This is primarily due to the high prevalence rates, as well as significant changes in the dentoalveolar system observed in this pathology. Various causes, both local and general, can contribute to the development of pathological processes in the periodontium. In this regard, prevention issues are of particular scientific and practical interest, since periodontal diseases are observed in almost all age groups of the population. The review article presents the main directions of prevention of periodontal diseases.
Эпидемическая ситуация по туберкулезу в Удмуртской Республике, Республике Татарстан, Республике Коми в 2019 году
Authors: Сысоев П.Г. , Акимова Д.А. , Толстова А.В.
Published: May 2021

This article is devoted to the epidemic situation of tuberculosis in the republics of Udmurtia, Tatarstan and Komi in 2019. The main epidemiological indicators of tuberculosis in the republics were assessed. Conclusions were made on the basis of the study
Use of increased concentrations of adenosinediphosphate for high residual platelet reactivity in patients with coronary heart disease
Authors: Trubacheva O.A. , Belyaeva S.N. , Suslova T.E. , Petrova I.V.
Published: May 2021

Detection of a tendency to increased thrombosis in patients with coronary heart disease (CHD) is of important prognostic value in the selection of drugs aimed at achieving a persistent antithrombotic effect. The aim of the study was to evaluate the use of elevated ADP inducer concentrations to improve the accuracy of ADP-induced platelet aggregation in patients with coronary heart disease. Material and method. Material and method. We studied 48 patients with CHD who were on continuous double antiplatelet therapy for 6 months (aspirin 75mg and clopidogrel 75mg per day). The aggregation activity of the platelet suspension was studied using the Born method G. in the modification of Gabbasov Z. A. Platelet activity was evaluated by the degree of aggregation of platelet-rich plasma along the light transmission curve under the influence of the inducer adenosine diphosphate (ADP) at a concentration of 2 mmol/l and by its own patented method against the background of additional ADP application. Results. In patients, platelet aggregation decreased to 5-35% (p<0.005) compared to the standard values, which are 50-60%. The values of platelet aggregation with the additional introduction of the inducer of aggregation ADP in a ratio of 2:1 to 2 µmol/l for 1, 2, 3, and 4-minute registration of platelet aggregation, resulted in increased aggregation from 55% to 75% (p<0.001), indicating high residual platelet reactivity on the background of double antiplatelet therapy. Correlations of the degree of aggregation for elevated ADP concentrations with multivessel arterial lesion and dyslipidemia were also found, r=0.86 and r=0.92, respectively. Conclusion. The use of elevated concentrations of adenosine diphosphate in platelet aggregation in patients with ischemic heart disease increases the accuracy of assessing ADP-induced platelet aggregation against the background of dual antiplatelet therapy and contributes to the detection of high residual platelet reactivity.
Контрольно-измерительные электрохимические приборы
Authors: Мамелина Т.Ю.
Published: May 2021

The article deals with the types of control and measuring electrochemical devices and equipment, the ph meter is considered in detail.
Исследование возможности получения сорбционных материалов путем термического и химического модифицирования стеблей подсолнечника
Authors: Моисеенко Н.В. , Красникова Е.М
Published: May 2021

Исследование возможности получения сорбционных материалов путем термического и химического модифицирования стеблей подсолнечника
Организация научно-исследовательской работы школьников по теме «Поливинилацетат»
Authors: Мошнинова Т.М
Published: May 2021

The article deals with the organization of research work on the subject of chemistry on the topic "Polymers" studied in the 9th grade on the basis of the textbook of O. S. Gabrielyan.This paper describes the importance of research work in school. The topics of research works for students on the topic "polyvinyl Acetate"are presented.
Разработка конспекта урока на тему «Элементы-металлы. Особенности строения их атомов. Положение металлов в периодической системе Д.И. Менделеева»
Authors: Сапарова А.С. , Сафина Л.Г.
Published: May 2021

The outline of the lesson on the topic Metal elements has been developed. Features of the structure of their atoms. The position of metals in the periodic system of D.I. Mendeleev.
Некоторые принципы построения набережных ландшафтов
Authors: Мочалова Е.Ю.
Published: May 2021

В работе представлен анализ двух современных набережных. В результате выявлены основные принципы их композиционного построения. Данная статья выдвигает идеи гуманистического экологического подхода к проектированию и развития территорий урбанизированных набережных.
Опыт проведения дистанционной олимпиады по теории вероятностей в техническом вузе
Authors: Залукаева О.В.
Published: May 2021

The article analyzed the experience of distance Olympiad about theory of chances. It was in technical university. In this article demonstrates the tasks that were proposed for solving. This was a qualitative assessment of the results was carried out. The solution of several tasks is analyzed.