bluuebunny/crossref_metadata_2025 huggingface dataset:
Educación patrimonial y redes sociales. De la investigación a la acción: El proyecto Educación Patrimonial
Authors: Maldonado Esteras Stella
Published: January 2023

Los medios de comunicación social 2.0 han supuesto un viraje en muchos procesos de desarrollo, de comunicarnos, de relacionarnos. A día de hoy, no utilizamos las tecnologías digitales para obtener única y exclusivamente información. La web 2.0 nos ha brindado una nueva sociedad, no sólo de la información y el conocimiento, sino también del diálogo y la opinión abierta, los aprendizajes múltiples, la compartición y la creación de redes que no escapan a ninguna disciplina. El patrimonio es una de estas disciplinas presentes en las redes sociales.

Partiendo de dos momentos o etapas de investigación, hemos ido analizando la presencia del patrimonio en estos contextos, en busca de ejemplos de educación patrimonial. Y hemos dado con modelos de comunicación del patrimonio que se adecuan a los nuevos lenguajes. Nuestra intención on estos estudios era ir construyendo, partiendo de la realidad existente, una acción educomunicativa y metodológica con base en la investigación-acción como práctica educativa y evaluativa. De esta forma surge Educación Patrimonial, en desarrollo actualmente, con la motivación de trabajar con diferentes patrimonios, estableciendo vínculos entre éstos y las personas.
Educación en diversidad sexual a través de las Artes Plásticas. Práctica en la Escuela de Arte y Superior Fernando Estévez de Tenerife
Authors: Moreno Candel Francisco
Published: January 2023

En este artículo describimos un trabajo teórico/práctico volcado en la atención a la diversidad sexual en la educación y llevando dicha temática a las aulas. Para ello, realizamos un breve análisis de la situación actual en la educación en relación con la diversidad sexual. Posteriormente, proponemos la defensa de las funciones de la formación artística para el desarrollo de los valores sociales, los cuales resultan muy útiles para la educación en la diversidad, apoyándonos en una experiencia educativa realizada con la ayuda del alumnado de la Escuela de Arte y Superior de Diseño Fernando Estévez, en Santa Cruz de Tenerife. Dicha práctica, fue enfocada con el objetivo de trabajar la diversidad sexual y la deconstrucción de los estereotipos imperantes en la cultura visual. Así, tratamos de demostrar cuán fácil y eficaz es la aplicación de cualquier problemática de esta índole a los currículos artísticos, y sus efectivos resultados. Concluida la práctica, hemos podido identificar dicha temática como un problema real y valorar positivamente la eficacia de la educación artística, subrayando sus herramientas como vías de trabajo adecuadas para la formación en valores.
Directores y directoras de los centros de educación infantil y educación primaria en la comunidad de Asturias. Percepción de su formación, funciones y competencias.
Authors: González Álvarez María
Published: January 2023

En el presente estudio pretendemos estudiar la situación profesional de directores/as de Educación Infantil y Primaria de la Comunidad de Asturias. Como objetivos del trabajo proponemos analizar su formación inicial y permanente, satisfacción en el ejercicio del cargo, importancia de la dirección para el funcionamiento del centro y de la calidad de la enseñanza, el apoyo y colaboración que reciben. Para ello hemos elaborado una prueba que ha sido enviada por correo electrónico y recibida mediante la correspondiente aplicación de Google a una muestra de directores/as de las enseñanzas referidas elegida al azar y en función de la titularidad del centro. Prueba que ha sido cumplimentada por sesenta y siete directores/as. Como conclusiones del trabajo podemos señalar que procede mejorar los programas de formación inicial y permanente de la función directiva. Directores/as se encuentran bastante satisfechos en el ejercicio de sus responsabilidades, considerando como importante la misma para el buen funcionamiento del centro y la calidad de la enseñanza. Entienden que reciben en sus tareas un razonable apoyo, colaboración y reconocimiento. Las administraciones educativas deben apoyar la función directiva.
The uses of public relations employees in Al-Ahsa hospitals for social networking sites and their use in raising awareness of Corona disease
Authors: Ali Fouda , Al-Naeem Latifa
Published: January 2023

Abstract The objective of this study was to identify the uses of public relations employees in Al-Ahsa hospitals for social networking sites and the relationship between this use and employing it to raise awareness of Corona disease, as well as to identify social communication activities by public relations employees to manage the stages of the Corona virus crisis, the sources of information they use, and the communication patterns they provide, as well as the effectiveness of public relations. The study's findings were based on the comprehensive survey method and the analytical-descriptive method. Due to the small size of the study population, the entire community was used as a sample for the study, with a total of 61 male and female employees as of the time the study was conducted. Twitter ranked first among the most popular websites, with a usage rate of 35.9%, while Google Chrome ranked last, with a usage rate of 1.9% of the total study sample. Additionally, the rate of using social media to raise awareness of the dangers of Corona disease was (always) high, at 60%. The results also indicate that the pattern of providing information of the type "tweet / publication" ranked first with a rate of 29.9%, while the pattern of providing information of the type "animated infographic" ranked last with a rate of 8.5% of the total study sample, and that there is a weak direct relationship between the use of social networking sites and the level of awareness of the risks of Corona disease, and a medium direct relationship between the use of social networking sites and the level of awareness of the (0.05). Keywords: Al-Ahsa hospitals, uses and gratifications, Corona pandemic, public relations employees.
Vocación y burnout en docentes mexicanos
Authors: Torres-Hernández Edgar Fabián
Published: January 2023

El creciente ritmo de exigencias y urgentes adaptaciones en el plano sanitario, social y profesional demandan de los individuos una respuesta que, para algunos, puede sobrepasar sus límites; la profesión docente no es la excepción puesto que es una actividad de constantes retos y rupturas epistemológicas y culturales. El fenómeno de burnout o desgaste en el trabajo es cada día más patente y se ha estudiado en asociación con ciertas características de índole personal y contextual, sin embargo, no se tienen estudios suficientes que lo vinculen con la vocación a la docencia que puede responder como una fuente de soporte para evitar dicho desgaste. El propósito del presente trabajo es analizar la relación entre la vocación y el síndrome de burnout en el profesorado mexicano, además de analizar la validez de la escala de vocación a la docencia; para ello, se realizó un estudio cuantitativo, descriptivo y de amplitud transversal a 824 docentes de diversos todos los niveles educativos. Los resultados revelan una asociación predictiva y de corte negativa entre la vocación y el burnout, además de encontrarse diferencias significativas según las diferentes categorías sociolaborales; asimismo el análisis de la escala de vocación a la docencia reveló que es un instrumento fiable y válido para analizar dicho constructo. Se concluye que existen factores críticos que pueden detonar el desgaste laboral como la incertidumbre contractual, el nivel educativo en que se ejerce la docencia, la formación profesional y la experiencia en la docencia; se recomienda un acompañamiento integral al profesorado que permita su desarrollo profesional y humano.
Medios e instrumentos para evaluar los resultados de aprendizaje en másteres universitarios. Análisis de la percepción del profesorado sobre su práctica evaluativa.
Authors: Ibarra-Sáiz María Soledad , Rodríguez-Gómez Gregorio , Lukas-Mujika José Francisco , Santos-Berrondo Alaitz
Published: January 2023

Estudios previos sobre los medios e instrumentos de evaluación utilizados en la educación superior han puesto de manifiesto el uso mayoritario del examen final como principal fuente de valoración. Los avances en el conocimiento de los procesos de evaluación han evidenciado la necesidad de disponer de una mayor amplitud y diversidad de medios e instrumentos que permitan recabar una información rigurosa y válida sobre la que sustentar los juicios sobre el grado de aprendizaje del estudiantado. Este estudio se ha realizado en el contexto del Proyecto FLOASS (http://floass.uca.es) con la finalidad de explorar la percepción que sobre su práctica evaluativa tiene el profesorado. Se ha utilizado una metodología mixta, mediante un diseño secuencial exploratorio, que ha permitido recabar la percepción de 416 profesores, de seis universidades de diferentes comunidades autónomas, que cumplimentaron el cuestionario RAPEVA-Autoinforme del profesorado sobre su práctica en la evaluación de los resultados de aprendizaje. Entre los medios más utilizados destaca la participación, las pruebas de resolución de problema, pruebas de desempeño, objetos digitales o presentaciones multimedia y los proyectos y las rúbricas o el argumentario evaluativo entre los instrumentos de evaluación. Se han encontrado las mayores diferencias en función de la universidad, el ámbito de conocimiento o el grado de seguridad y satisfacción con el sistema de evaluación. En el caso del género o la experiencia las diferencias son menores o inexistentes. Se aportan futuras líneas de investigación que posibiliten una mayor comprensión de la práctica evaluativa en la educación superior.
Evaluación de la Competencia Digital Docente: instrumentos, resultados y propuestas. Revisión sistemática de la literatura
Authors: García-Ruiz Rosa , Buenestado-Fernández Mariana , Ramírez-Montoya Maria Soledad
Published: January 2023

La competencia digital docente (CDD) es un reto en la práctica profesional del profesorado y un problema identificado en la investigación al que dar respuestas. En concreto, la evaluación de la CDD es un elemento clave para tomar decisiones respecto a la formación de los docentes y a futuras líneas de investigación. Tomando este reto como foco, el objetivo de este artículo es proporcionar un panorama actualizado sobre las herramientas utilizadas en los procesos de evaluación de la competencia digital de los docentes, indagando en el tipo de diseño de investigación, instrumentos y análisis utilizados, así como los resultados obtenidos tras su aplicación y sus implicaciones. El estudio realizado se aborda desde una revisión sistemática de la literatura, siguiendo las directrices marcadas en la declaración PRISMA, con una muestra de 66 artículos publicados entre 2017 y febrero de 2022 en revistas indexadas en la Web of Science y Scopus, en los que se evalúa la CDD. Los resultados obtenidos muestran niveles medios y bajos de CDD diagnosticados y ofrecen evidencias de la relevancia de la evaluación de la CDD para su mejora. Así mismo evidencian que el marco europeo DIGCOMPEDU y el español propuesto por el INTEF, son seguidos por investigadores de todo el mundo. Sin embargo, es una práctica habitual que los investigadores elaboren su propio instrumento para evaluar la CDD, siendo el cuestionario de autoevaluación el utilizado en la mayor parte de los estudios, al tiempo que se recomienda complementarlo con otras herramientas cualitativas para evaluar el nivel real adquirido. Las conclusiones ponen de manifiesto que los investigadores coinciden en reclamar dos aspectos fundamentales: aumentar la formación docente en competencia digital y avanzar en diseños de investigación que permitan comprobar cómo mejora el nivel CDD a través de propuestas formativas contextualizadas a la etapa educativa o tipo de enseñanza.
Changing Working Conditions in the context of Digital Activism in the Turkish TV Sector
Authors: Banu DALAMAN Zeynep , DEMİRTAŞ Mine
Published: January 2023

Kadın hareketi günümüzde dijital aktivizm ile farklı bir boyuta taşınmıştır. Kadınlar ayni işe eşit ücret, çalışma koşulların iyileştirilmesi ve işyerinde uğradıkları taciz gibi konuları dijital platformlara ve sosyal medyaya taşıyarak
yeni bir aktivizm oluşturmuşlar ve bu aktivizm hareketi tüm dünyada dizi ve film sektörüne de taşınmıştır. Amerikan sinema sektöründe cinsel taciz ve saldırılara karşı başlayan hareketler #MeToo ve #TimesUp etiketleriyle dijital
bir kadın aktivizmine dönüşmüş, sosyal ağlarda cinsel taciz kınanarak toplumsal cinsiyet eşitliği teşvik edilmiştir. Medyada ve özellikle televizyon dizilerinde ataerkil bakış açısıyla kadınların yetersiz temsili devam ediyor olsa
da, #TimesUp hareketi ile kamera önündeki ve arkasındaki kadın sayısının artırılması ve toplumsal hareketlerin etkilerinin medya prodüksiyonlarına yerleştirilmesi gerektiği savunulmuştur. Bu bağlamda, #susmabitsin #sendeanlat etiketiyle
#MeToo hareketine destek verilerek, konu Türkiye’deki dizi ve film sektörlerine de taşınmıştır. Gerek #MeToo gerekse #TimesUp kadın hareketleriyle oluşan dijital aktivizmin Türkiye’de televizyon dizilerinin senaryolarına ve set
çalışma ortamlarına ne denli etkili olduğunun incelenmesi, bu çalışmanın amacını oluşturmaktadır. Araştırmada yöntem olarak, Türkiye’de en çok seyredilen kadın temalı iki televizyon dizisi olan “Yasak Elma” ve “Evlilik Hakkında
Her Şey” adlı diziler ele alınmış, feminist bakış açısıyla #MeToo akımının ve #TimesUp organizasyonunun Türkiye’de dizi sektöründe çalışma koşullarını nasıl etkilediği sorgulanmıştır. Adı geçen dizilerin setlerinde gözlem yapılarak,
bu dizilerin oyuncuları, yapımcıları ve yönetmenleriyle derinlemesine görüşmeler yapılmıştır. Bu çalışmanın yürütülmesi hususunda, İstanbul Topkapı Üniversitesi Akademik Araştırma ve Yayın Etiği Kurulu tarafınca 06/2022 tarihli
ve 2022/05 sayılı etik kurul kararı ile onay alınmıştır.
Externalities of Education and Its Effect on Social Systems
Authors: UZUN Fuat
Published: January 2023

Eğitimin toplumda birçok alanla ilişkili olduğu, bu alanları olumlu yönde etkilediği ve geliştirdiği eğitim bilimcileri tarafından vurgulanan ve araştırmalarla ortaya konan bir olgudur. Eğitimin belirgin etkileri kadar çoğu zaman doğrudan
hissedilmeyen dolaylı etkileri sayesinde bireylere ve topluma fayda sağladığı görülmektedir. Eğitimin ölçülmesi son derece zor olan dışsallıklar olarak isimlendirilen faydaların temeli, insanların kişisel yaşantılarında kayda değer
bir rol oynaması, bunun da toplumun tamamına yansımasıdır. Eğitim bilimciler tarafından eğitimin dışsallıklarını ölçmeye yönelik yapılan ampirik çalışmalar bu konuda önemli sonuçlar içermektedir. Bu çalışmalarda eğitime yapılan
yatırımların mali ve mali olmayan önem derecesi yüksek katkılar sağladığı ve bu katkıların eğitime yapılan yatırımlardan iki kat daha yüksek olduğu ortaya konulmuştur. Eğitimin dışsallıkları ekonomideki üretim artışında, tüketim
kültüründe, birey ve toplumların eğitime yönelik tutumlarında, sağlık alanında bilinçli toplum yaratılmasında, teknoloji ve inovasyon alanında yeniliklerin ortaya çıkmasında, toplumda suç oranlarının azalmasında, bebek ölüm oranının
azalmasında, kadınların çocuk sahibi olma yaşı vb. olumlu olarak hissedilmektedir. Eğitimin uzun vadeli etkisiyle potansiyel kazancın arttığı ve suçları azalttığı, bireyin kendini yetkinleştirecek öğrenmeyi sağladığı, psikolojik
durumlarını olumlu yönde etkilediği, bireyin gelecekteki sosyal ağlarını birlikte belirlemeye ve akranları ile uyum içinde yaşamaya katkı sağladığı görülmektedir. Dışsallıkların ölçeği ve kapsamı bilindiğinde, yapılacak maliyet
ve fayda analizleri ile eğitime ayrılan kamusal yatırımların yerinde ve uygun olması sağlanabilir. Bu araştırma "betimleyici" olup, "literatür taraması" yöntemi kullanılmıştır. Bu çalışma 2018 yılından günümüze kadar olan zaman
dilimini kapsamaktadır. Araştırmada konuyla ilgili belge ve raporlar derinlemesine incelenmiş, duruma göre durum ve temalar tanımlanarak nitel araştırma yaklaşımı izlenmiştir.
Guidance on Fiqhial Issues According to Ibn Abd al-Barr al-Maliki
Authors: MURAD Shavish
Published: January 2023

Fıkhi meselelerdeki delil, o meselerin ruhu ve nefesidir. Çünkü fıkıh; nazar/istidlal/fikir yürütme ile kavranmaktadır. Şeri hükümleri tam anlamıyla bilmeyi sağlayacak akıl yürütme, ancak istidlale dayanmalıdır. İstidlâl talep edilene
(hükme) götüren şeydir. Fıkıh meselelerindeki temellendirme; meselelerin asıllarını açıklayan deliller aracılığıyla fıkhi meselelerdeki görüş ve fetvaları delillerine dayandırmak ve bunların şer‘i kaynaklarını açıklamaktır. Meseleleri
delillere dayandırma fıkhın ve fıkıh esasının özüdür. Şer‘i hükümleri istinbât eden alim bu hükümlerin delillerini bilmediği sürece ona alim denilmez. Çünkü fıkıh, şer‘î ameli hükümleri tafsili delillerinden öğrenmektir. Tüm bunlara
binaen her mezhep içinde mezhep imamlarının birçok sebepten dolayı gerekçelendirmedikleri bazı hükümleri daha sonra gerekçelendiren ve delilillerine dayandıran büyük alimler ortaya çıkmıştır. Böyle yapan alimlerden biri de İbn
Abdilber’dir ki onun birçok eserinde fıkhi meseleleri delillerine dayandırmadaki yöntemi; meseleleri sağlam bir şekilde temellendirme, onlar için güçlü bir delil getirme ve onları iyi bir şekilde açıklama şeklinde olmaktadır. Bu
çalışmada uygulamalı olarak fıkhî delilendirmenin önemini, bunun nasıl yapıldığını, konuya dair ibadet türünden ilmi uygulama örneklerini, buna dair meseleleri ve İbn Abdilber’in fıkhi temellendirme yönteminde öne çıkan yönlerinin
en önemlilerini ortaya koyduk. Fürû mesellerinin delillerine ilhak edilmesi, bunların şer‘î delillere nasıl dayandırıldığının öğrenilmesi, talil ve kıyas ile İslam Hukuku’nun devamlı gelişmesi ve verimli olması için alan açılması;
İslam hukukunun anlaşılması, gelişmesi, parlaması, elverişli olması; meydana gelen yeni mesellere cevap verilmesi; İslam hukukunun yolu, maksadı ve gayesininin dışına çıkmadan bu tür meselelere çözüm üretilmesi için fıkhi meseleleri
delillerine dayandırma önem arz etmektedir.
Ultrasound-guided Percutaneous Drainage of Intra-abdominal Collection and its Clinical Outcome: A Prospective Interventional Study
Authors: Agarwal Sushant , Duara Bijit Kumar , Ahmed Rajib , Bhaskar Das Bhaskar Das
Published: January 2023

Introduction: Intra-abdominal collections are abscesses that occur within the peritoneal cavity, the pelvis or behind the peritoneum (retroperitoneum) or intra-parenchymal. They are common complications of colorectal disease, particularly inflammatory bowel disease, malignancy and trauma. Ultrasound is very useful in establishing the diagnosis, quantification and localisation of intraabdominal abscesses. Open Surgical Drainage (SD) used to be the traditional treatment protocol. Recently however, percutaneous drainage procedures are becoming an essential therapeutic strategy in the treatment of this condition. Aim: To study the therapeutic efficacy of ultrasound-guided drainage of abdominal abscess and to compare it with open SD. Materials and Methods: A prospective interventional study was conducted in 94 patients with intra-abdominal abscess at Gauhati Medical College and Hospital, Guwahati, Assam, India, in between July 2019 to June 2020 who were randomly allocated into two groups and underwent respective procedures. The first group was Percutaneous Catheter Drainage (PCD) and second group was open Surgical Drainage (SD) group. Patient demographics, symptoms, aetiologies and locations of the collections as well as duration of hospital stay, success rate, and complications were analysed. Results of radiological findings were tabulated, evaluated and collated between both the groups. Statistical Package for Social Sciences (SPSS) software 21.0 version was used for analysing data and p-value <0.05 was considered significant. Results: For abdominal collections and abscesses, ultrasound guided percutaneous drainage was successful in 96.8% of the patients whereas it was successful in 80% cases in the SD group. Complications were more frequently encountered in patients who underwent open SD (16.70%) compared to percutaneous drainage (12.40%) which was significant (p-value 0.0136). The average duration of stay for the group undergoing percutaneous drainage was 9.13±1.62 days which was shorter than for the group undergoing SD was 11.10±1.75 days (p-value <0.001). The overall rate of failed percutaneous drainage was 3.2% as compared to SD where it was 20%. Conclusion: This study concluded that image-guided percutaneous drainage has lesser complications and higher success rate for abdominal collections/abscesses as compared to SD. Due to lower mortality rates as well as shorter duration of hospitalisation than open SD it can replace the traditional open or laparoscopic approach of drainage in most cases.
Wind Speed Thresholds for Adjusting Conventional Design Criteria for the Ventilated Improved Pit Latrine without Compromising Odour Control
Authors: Obeng Peter Appiah , Awere Eric , Obeng Panin Asirifua , Oteng-Peprah Michael , Barnie Samuel
Published: January 2023

Aims: The objective of this paper is to re-evaluate the wind speed threshold at which the 100 mm polyvinyl chloride (PVC) vent pipe may be used without compromising the ventilation rate required for effective odor control in a ventilated improved pit (VIP) latrine. The paper also sought to investigate the chances of leveraging upon high wind speeds to grant user preferences for multiple windows and installation of insect screens, which are conventionally forbidden.

Study Design: A comparative experimental design was carried out in a VIP latrine with internal cubicle dimensions of 1.2 m x 1.5 m built over a pit of cross-section 1.2 m x 2.5 m and depth of 3.0 m which was fitted with a 100 mm PVC vent pipe.

Place and Duration of Study: The experimental setup was located on the compound of a public basic school in Prampram, a peri-urban coastal community in Southern Ghana. The setup was monitored for twelve hours a day (5 am to 5 pm) for twelve days.

Methodology: The experimental setups comprised of four designs of the VIP latrine: single-window and multi-window designs each with and without insect screen in the window. The ventilation rate in each modified design was monitored simultaneously with the external wind speed.

Results: The results of the study indicate that the 100 mm PVC vent pipe could attain the recommended ventilation rate of 20 m3/h at an average wind speed as slow as 1.5 m/s as compared to the 3 m/s previously suggested.  The influence of wind speed on the ventilation rate is insignificant at wind speed variations not exceeding 0.5 m/s when the 100 mm PVC vent pipe is used.

Conclusion: At an average wind speed of 1.5 m/s, either the multiple-window design or insect screen used in combination with the 100 mm PVC vent pipe could attain the recommended ventilation rate and should not be outrightly forbidden. However, a wind speed threshold of 2.5 m/s is required for the adoption of the multi-window design with insect screens when the 100 mm PVC vent pipe is used.
Sulfur Mismatch Substitution in Layered Double Hydroxides as Efficient Oxygen Electrocatalysts for Flexible Zinc–Air Batteries
Authors: Han Xiaotong , Li Nannan , Baik Jae Sung , Xiong Peixun , Kang Yingbo , Dou Qingyun , Liu Qing , Lee Jin Yong , Kim Chul Sung , Park Ho Seok
Published: January 2023

Although layered double hydroxides (LDHs) are extensively investigated for oxygen electrocatalysis, their development is hampered by their limited active sites and sluggish reaction kinetics. Here, sulfur mismatch substitution of NiFe–LDH (S–LDH) is demonstrated, which are in‐situ deposited on nitrogen‐doped graphene (S–LDH/NG). This atomic‐level sulfur incorporation leads to the construction of the tailored topological microstructure and the modulated electronic structure for the improved catalytic activity and durability of bifunctional electrocatalysts. The combined computational and experimental results clarify that the electron transfer between the sulfur anion and Fe3+ generates the high‐valence Fe4+ species, while the mismatch substitution of the sulfur anion induces the metallic conductivity, an increased carrier density, and the reduced reaction barrier. Consequently, the as‐fabricated Zn–air battery achieves a high power density of 165 mW cm‐2, a large energy density of 772 Wh kgZn‐1 at 5 mA cm‐2, and long cycle stability for 120 h, demonstrating its real‐life operation.
Synergistic Solvation of Anion: An Effective Strategy toward Economical High‐Performance Dual‐Ion Battery
Authors: Wang Boyu , Huang Yuhao , Wang Ying , Wang Hongyu
Published: January 2023

The solvation structure of anion plays a crucial role in determining the performance of dual‐ion batteries using graphite‐positive electrodes. In past research on dual‐ion batteries, the design criteria of electrolyte solutions were largely based on the traditional relationship between solvents and additives. Here, a distinctive synergistic solvation strategy is proposed for the design of electrolyte solutions. Despite some solvents performing poorly or even failing to operate when they are used alone for electrolyte solutions, an unexpected improved performance appears when they are combined based on their characteristic moieties. Based on the synergistic solvation strategy, an economical electrolyte solution system (LiPF6‐methyl acetate/diethyl carbonate) is successfully designed. The intercalation behavior of the solvated anion from this solution into the graphite electrode is investigated by conventional electrochemical tests, in situ electrochemical characterizations and theoretical calculations. A proof‐of‐concept dual‐ion battery based on this electrolyte solution delivers a discharge capacity of 100.08 mAh g−1 and ≈4.67 V medium discharge voltage at 10C (1 A g−1), along with 85.35% capacity retention after 1000 cycles at 5C. Moreover, this battery exhibits 93.8% of its room‐temperature capacity at −20 °C and can even work at −70 °C. Synergistic solvation offers a novel approach to design electrolyte solutions for dual‐ion batteries.
Stress Induced Color and Pattern for Information Coding
Authors: Bai Jing , Zhang Luzhi , Shi Zixing , Jiang Xuesong
Published: January 2023

On the process of deforming polymer, its morphologies can be vividly observed and reflected via the internal stress distribution under the polarized light due to its special stretched birefringence, which gives a new way to store and read information. Inspired by this vivid character, a novel crosslinked polyurethane (PU) is designed and used as matrix for coding information, in which aluminum acetylacetonate works as the crosslinker to form dynamical crosslinked structure with coordinated bonds. By tailoring these two bonds via a region‐selective regulation, the information can be written in the crosslinked PU. Only under the polarized light, the coded information can be read as stress induced color on the deformed state. After its recovery, 2D pattern can be simultaneously formed on the surface of the film. Therefore, the information is expressed in multiple channels. Thanks to the dynamic character, the information can be also erased and rewritten. Therefore, it is a new method for information coding with a high security, which has a wide range of potential applications in data storage, anticounterfeiting labeling, information conversion, and other areas.
Plant‐Derived Vesicle‐Like Nanoparticles as Promising Biotherapeutic Tools: Present and Future
Authors: Feng Junjie , Xiu Qi , Huang Yiyao , Troyer Zach , Li Bo , Zheng Lei
Published: January 2023

Extracellular vesicles (EVs) are heterogeneous, phospholipid bilayer‐enclosed biological particles that regulate cell communication by molecular cargo delivery and surface signaling. EVs are secreted by almost all living cells, including plant cells. Plant‐derived vesicle‐like nanoparticles (PDVLNs) is a generic term referring to vesicle‐like nanostructure particles isolated from plants. Their low immunogenicity and wide availability make PDVLNs safer and more economical to be developed as therapeutic agents and drug carriers. Accumulating evidence indicates the key roles of PDVLNs in regulating interkingdom crosstalk between humans and plants. PDVLNs are capable of entering the human‐body systemand delivering effector molecules to cells that modulate cell‐signaling pathways. PDVLNs released by or obtained from plants thus have great influenceon human health and diseases. In this review, the biogenesis, detailed preparation methods, various physical and biochemical characteristics, biosafety, and preservation of PDVLNs are introduced, along with how these characteristics pertain to their biosafety and preservability. The potential applications of PDVLNs on different plant and mammalian diseases and PDVLN research standardization are then systematically discussed.
Recent Progress of Hollow Carbon Nanocages: General Design Fundamentals and Diversified Electrochemical Applications
Authors: Li Zesheng , Li Bolin , Yu Changlin , Wang Hongqiang , Li Qingyu
Published: January 2023

Hollow carbon nanocages (HCNCs) consisting of sp2 carbon shells featured by a hollow interior cavity with defective microchannels (or customized mesopores) across the carbon shells, high specific surface area, and tunable electronic structure, are quilt different from the other nanocarbons such as carbon nanotubes and graphene. These structural and morphological characteristics make HCNCs a new platform for advanced electrochemical energy storage and conversion. This review focuses on the controllable preparation, structural regulation, and modification of HCNCs, as well as their electrochemical functions and applications as energy storage materials and electrocatalytic conversion materials. The metal single atoms‐functionalized structures and electrochemical properties of HCNCs are summarized systematically and deeply. The research challenges and trends are also envisaged for deepening and extending the study and application of this hollow carbon material. The development of multifunctional carbon‐based composite nanocages provides a new idea and method for improving the energy density, power density, and volume performance of electrochemical energy storage and conversion devices.
Assessment of renal outcome following therapy in monoclonal immunoglobulin deposition disease: Emphasizing the need for a consensus approach
Authors: Pianko Matthew J. , Tiutan Timothy , Derkach Andriy , Flynn Jessica , Salvatore Steven P. , Jaffer‐Sathick Insara , Rossi Adriana C. , Lahoud Oscar , Hultcrantz Malin , Shah Urvi A. , Maclachlan Kylee , Chung David J. , Shah Gunjan L. , Landau Heather J. , Korde Neha , Mailankody Sham , Lesokhin Alexander M. , Tan Carlyn , Scordo Michael , Jaimes Edgar A. , Giralt Sergio A. , Usmani Saad , Hassoun Hani
Published: January 2023

Monoclonal immunoglobulin deposition disease (MIDD), often associated with plasma cell dyscrasias, predominantly affects the kidneys. In this disease, hematologic response (HR) to treatment can be reliably assessed by International Myeloma Working Group (IMWG) consensus criteria, while uniform criteria for assessing renal response are lacking. We report a retrospective analysis of renal outcomes among 34 patients with MIDD. With most patients treated with bortezomib and autologous stem cell transplantation, 26 of 28 (94%) achieved very good partial HR or better. We demonstrate that both IMWG (based on estimated glomerular filtration rate, eGFR) and amyloid (based on proteinuria) criteria are needed to capture renal response: among 28 evaluable patients, 6 (21%) had isolated proteinuria, while 13 (46%) had isolated decreased eGFR. Using both criteria, which were concordant in patients with both decreased eGFR and proteinuria, 22 of 28 patients (79%) achieved a renal response, including 2 of 7 discontinuing dialyses. All 6 patients (100%) with isolated proteinuria and 7 of 13 (54%) with isolated decreased eGFR achieved renal response, suggesting that isolated proteinuria is an early manifestation of MIDD associated with reversible renal damage. Baseline eGFR predicted renal response (p = .02 by quartile) and survival (p = .02), while HR (CR vs. non‐CR) did not, probably because of high HR rate. With a median follow‐up of 110 months, the median overall survival was 136 months (95% CI: 79–NR) and median renal survival had not been reached. Prospective studies using uniform renal response criteria are needed to optimize the management of MIDD.
Survival trends in young patients with Waldenström macroglobulinemia: Over five decades of experience
Authors: Chohan Karan L. , Paludo Jonas , Vallumsetla Nishanth , Larson Dirk , King Rebecca L. , He Rong , Gonsalves Wilson , Inwards David , Witzig Thomas E. , Swaika Abhisek , Jain Tania , Leung Nelson , Ailawadhi Sikander , Reeder Craig B. , Lacy Martha Q. , Rajkumar S. Vincent , Kumar Shaji , Kyle Robert A. , Gertz Morie A. , Ansell Stephen M. , Kapoor Prashant
Published: January 2023

Waldenström macroglobulinemia (WM) is a rare, indolent lymphoma, that predominately affects the elderly. We report the outcomes of young WM patients, evaluated over five decades, compared to their older counterparts, matched for the time of diagnosis. Between January 1, 1960 and October 31, 2013, 140 (11.8%) WM patients were ≤50 years of age at diagnosis in our database, and their estimated 10‐year overall survival (OS) was 74%, with death attributable to WM in a higher proportion of patients compared to their older (≥65 years) counterparts (91% vs. 58%, p = .0001). Young patients were grouped into three cohorts based on the timing of the initiation of therapy: Group 1 (1960–1977, n = 12), Group 2 (1978–1995, n = 48), and Group 3 (1996–2013, n = 74). Among young patients, there was no disease‐specific survival (DSS) difference across the three periods, [median DSS at 13 years (95% CI 5–23), 16 years (95% CI 14–22), and 15 years (95% CI 10‐NR; p = .41), respectively]. However, DSS for the older cohort incrementally improved (Group 1, median 5.2 years, Group 2: 9.6 years, Group 3: 12 years; p = .05) over these periods. The estimated average years‐of‐life lost for the young cohort was 11.2 years from diagnosis, based on the expected survival for a normal age‐ and sex‐matched population. Despite a protracted disease course, nearly all young patients succumb to their disease. In contrast to the improved survival of the elderly patient population, the evolving treatment strategies in WM have not impacted the outcome of young patients; however, the impact of Bruton tyrosine kinase inhibitors on this unique patient population remains to be determined.
Multisite ALLFTD study modeling progressive empathy loss from the earliest stages of behavioral variant frontotemporal dementia
Authors: Toller Gianina , Cobigo Yann , Callahan Patrick , Appleby Brian S. , Brushaber Danielle , Domoto‐Reilly Kimiko , Forsberg Leah K. , Ghoshal Nupur , Graff‐Radford Jonathan , Graff‐Radford Neil R. , Grossman Murray , Heuer Hilary W. , Kornak John , Kremers Walter , Lapid Maria I. , Leger Gabriel , Litvan Irene , Mackenzie Ian R. , Pascual Maria B. , Ramos Eliana M. , Rascovsky Katya , Rojas Julio C. , Staffaroni Adam M. , Tartaglia Maria C. , Toga Arthur , Weintraub Sandra , Wszolek Zbigniew K. , Boeve Brad F. , Boxer Adam L. , Rosen Howard J. , Rankin Katherine P. ,   the ALLFTD consortium
Published: January 2023

Introduction

Empathy relies on fronto‐cingular and temporal networks that are selectively vulnerable in behavioral variant frontotemporal dementia (bvFTD). This study modeled when in the disease process empathy changes begin, and how they progress.

Methods

Four hundred thirty‐one individuals with asymptomatic genetic FTD (n = 114), genetic and sporadic bvFTD (n = 317), and 163 asymptomatic non‐carrier controls were enrolled. In sub‐samples, we investigated empathy measured by the informant‐based Interpersonal Reactivity Index (IRI) at each disease stage and over time (n = 91), and its correspondence to underlying atrophy (n = 51).

Results

Empathic concern (estimate = 4.38, 95% confidence interval [CI] = 2.79, 5.97; p < 0.001) and perspective taking (estimate = 5.64, 95% CI = 3.81, 7.48; p < 0.001) scores declined between the asymptomatic and very mild symptomatic stages regardless of pathogenic variant status. More rapid loss of empathy corresponded with subcortical atrophy.

Discussion

Loss of empathy is an early and progressive symptom of bvFTD that is measurable by IRI informant ratings and can be used to monitor behavior in neuropsychiatry practice and treatment trials.
Biochemical Analysis Leads to Improved Orthogonal Bioluminescent Tools
Authors: Williams Sierra J. , Gewing‐Mullins Jordan A. , Lieberman Whitney K. , Kolbaba‐Kartchner Bethany , Iqbal Reema , Burgess Hana M. , Colee Clair M. , Ornelas Marya Y. , Reid‐McLaughlin Edison S. , Mills Jeremy H. , Prescher Jennifer A. , Leconte Aaron M.
Published: January 2023

Engineered luciferase‐luciferin pairs have expanded the number of cellular targets that can be visualized in tandem. While light production relies on selective processing of synthetic luciferins by mutant luciferases, little is known about the origin of selectivity. The development of new and improved pairs requires a better understanding of the structure−function relationship of bioluminescent probes. In this work, we report a biochemical approach to assessing and optimizing two popular bioluminescent pairs: Cashew/d‐luc and Pecan/4′‐BrLuc. Single mutants derived from Cashew and Pecan revealed key residues for selectivity and thermal stability. Stability was further improved through a rational addition of beneficial residues. In addition to providing increased stability, the known stabilizing mutations surprisingly also improved selectivity. The resultant improved pair of luciferases are >100‐fold selective for their respective substrates and highly thermally stable. Collectively, this work highlights the importance of mechanistic insight for improving bioluminescent pairs and provides significantly improved Cashew and Pecan enzymes which should be immediately suitable for multicomponent imaging applications.
Synthesis of Isomeric Tb3+–Phthalocyanine Double‐Decker Complexes Depending on the Difference in the Direction of Coordination Plane and Their Magnetic Properties
Authors: Yamada Yasuyuki , Nakajima Hiroaki , Kobayashi Chisa , Shuku Yoshiaki , Awaga Kunio , Akine Shigehisa , Tanaka Kentaro
Published: January 2023

Invited for the cover of this issue are Kentaro Tanaka at Nagoya University and co‐workers. The image depicts three isomers of a terbium(III) phthalocyanine double‐decker complex made from C4h symmetrically substituted phthalocyanines and their magnetic properties. Read the full text of the article at 10.1002/chem.202203272.
Higher‐Order Cycloaddition Reactions for the Construction of Polycyclic Aromatic and Polycyclic Heteroaromatic Compounds
Authors: Bitsch René S. , Jessen Nicolaj Inunnguaq , Jørgensen Karl Anker
Published: January 2023

Cycloadditions are an important class of reactions in materials science for the construction of polycyclic aromatic and polycyclic heteroaromatic compounds. Recently, cycloadditions have been expanded beyond the “classical” group of cycloadditions involving six π‐electrons, and it is now possible to control cycloadditions for an extended number of π‐electrons by applying organocatalysis. This novel field of cycloadditions–termed higher‐order cycloadditions–allows new synthetic methodologies to construct polycyclic carbo‐ and heteroaromatic compounds in two or three dimensions. This concept presents higher‐order cycloadditions as a method for accessing two‐ and three‐dimensional azulenes and cyclazines, as well as three dimensional indenes, as polycyclic aromatic and polycyclic heteroaromatic compounds.
Top advances of the year: Leukemia
Authors: Kent Andrew , Pollyea Daniel A.
Published: December 2022

In the year 2021, there were three new Food and Drug Administration approvals for all leukemia types: asciminib (Scemblix) for chronic myeloid leukemia, brexucabtagene autoleucel (Tecartus) for relapsed/refractory B‐cell acute lymphocytic leukemia, and asparaginase erwinia chrysanthemi (recombinant)‐rywn (Rylaze) for acute lymphocytic leukemia. This is down from 2017–2018 when eight new therapies were approved for acute myeloid leukemia alone. However, this decrease from prior years does not imply that little progress was made in our understanding or treatment of leukemias in 2021. Asciminib and brexucabtagene autoleucel, in particular, are representative of major developing trends. Asciminib, a targeted therapy, is only one of many drugs in development that are products of a bedside‐to‐bench approach fueled by new sequencing and other genetic technologies that have greatly increased our understanding of the biology behind hematologic diseases. Brexucabtagene autoleucel, an adoptive cell therapy, is the newest of several similar treatments for B cell–associated neoplasms, and it is representative of a massive push to develop novel immunotherapies for a broad range of hematologic malignancies. This commentary reviews the development of asciminib and brexucabtagene autoleucel and describes other major advances in the associated fields of targeted therapy and immunotherapy for leukemias.
Cancer‐linked genetic testing: The key role of cultural influences
Authors: Nelson Bryn , Faquin William
Published: January 2023

This news section is written by a medical journalist and offers Cancer Cytopathology readers timely information on events, issues, and personalities of interest to the subspecialty. In this second of a two‐part series, genetic testing for hereditary cancers promises more targeted approaches to prevention and intervention, but cultural differences in perceptions of utility, autonomy, and decision‐making have a major impact on how such testing is conducted.
An effective veracity management for sentiment analysis in social media using crowdsourcing and multi‐set feature learning
Authors: Aruna Arulanandam Gnanaprakasam , Sangeetha Manickam
Published: December 2022

Recent innovations of the Internet‐of‐Things (IoT) are facilitated the data processing to an enormous scale. Nevertheless, the collected data are inherently uncertain because of noise, discrepancy, and incompleteness. To solve these constraints, improving data veracity is crucial for IoT‐based applications. As big data veracity is more critical, it must predict the veracity of tweets automatically for decision‐making. There have been many techniques developed including artificial intelligence and crowdsourcing models to estimate the veracity of tweets from single sources. But, these models are ineffective while the amount of crowd labels for tweets from multiple sources is not feasible. Also, analyzing the sentiment of public opinions has high complexity. Therefore, this article focuses on developing an efficient model to predict the veracity of tweets from multiple sources and analyze the sentiments of the passage. Primarily, different tweets with text labels are collected. Afterward, a crowdsourcing model is introduced which utilizes the crowdflower dataset to obtain the crowd labels for collected tweets. The Generative Adversarial Network (GAN) model is applied to increase the veracity of tweets by handling the low‐veracity tweets. Finally, the multi‐set feature learning model is implemented to classify the sentiment of opinions. The performance results manifest that the proposed model accomplishes superior accuracy of 97% than the classical veracity prediction models.
An optimization method for PLL‐based charge control SIMO Buck DC‐DC
Authors: Liu Yuyang , Wu Zhaohui , Li Bin , Zheng Yanqi , Chen Zhijian
Published: December 2022

The PLL‐based charge control scheme is optimized and implemented in a single‐inductor multiple‐output (SIMO) Buck DC‐DC in this paper. In order to decrease cross regulation (CR) during heavy load transient, the gain adaptive charge pump (GACP) is optimized to speed up the regulation of inductor current, and the current loop off‐time (CLOT) control is introduced to prevent the PLL‐based structure from frequency unlock. The proposed SIMO is designed in a 0.18 μm standard CMOS process. Experimental results show that the worst CR performance is 0.026 mV/mA, which is a 50% improvement of PLL‐based charge control scheme and 61.19% advantage above the existing charge‐controlled SIMO.
Algerian Youth and the Contestation over Sound on TikTok
Authors: Bruls Luca
Published: January 2023

In Algeria, youth form attitudes towards music as a result of their TikTok usage. The responses of governmental institutions, Facebook users, and middle‐class TikTokers to popular raï songs unfold the contestation over sound. Drawing on nethnography, I expose the moralizing and politicized responses that couple these different groups in their criticism. Through an account of the conversations and interactions with middle‐class Algerian youth, I demonstrate TikTok's subdivision into two opposed, yet interdependent scenes. The text draws on examples of the engagement between the two groups to reveal how youth call attention to their class identities by listening and sounding, as well as related expressions of dancing and dressing. The friendships and engagements online are a result of youth's scaling practices in TikTok's For You algorithm. Through their negotiation of songs, performances, and humour, middle‐class youth create a sonic class line that separates them from vulnerable classes. The moralizing stories that these middle‐class youth tell are an everyday representation of the different classes in Algeria. Studying sound on TikTok can help ethnographers learn about the concomitant memes and stereotypes that circulate online.
DEICA: A differential evolution‐based improved clustering algorithm for IoT‐based heterogeneous wireless sensor networks
Authors: Chaurasiya Sandip K. , Biswas Arindam , Nayyar Anand , Zaman Jhanjhi Noor , Banerjee Rajib
Published: January 2023

With the evolution of technology, many modern applications like habitat monitoring, environmental monitoring, disaster prediction and management, and telehealth care have been proposed on wireless sensor networks (WSNs) with Internet of Things (IoT) integration. However, the performance of these networks is restricted because of the various constraints imposed due to the participating sensor nodes, such as nonreplaceable limited power units, constrained computation, and limited storage. Power limitation is the most severe among these restrictions. Hence, the researchers have sought schemes enabling energy‐efficient network operations as the most crucial issue. A metaheuristic clustering scheme is proposed here to address this problem, which employs the differential evolution (DE) technique as a tool. The proposed scheme achieves improved network performance via the formulation of load‐balanced clusters, resulting in a more scalable and adaptable network. The proposed scheme considers multiple parameters such as nodes' energy level, degree, proximity, and population for suitable network partitioning. Through various simulation results and experimentation, it establishes its efficacy over state‐of‐the‐art schemes in respect of load‐balanced cluster formation, improved network lifetime, network resource utilization, and network throughput. The proposed scheme ensures up to 57.69%, 33.16%, and 57.74% gains in network lifetime, energy utilization, and data packet delivery under varying network configurations. Besides providing the quantitative analysis, a detailed statistical analysis has also been performed that describes the acceptability of the proposed scheme under different network configurations.
Iodine and Iodide in Reductive Transformations
Authors: Luján‐Montelongo J. Armando , Mateus‐Ruiz Jeferson B. , Valdez‐García Ricardo M.
Published: January 2023

This review provides a comprehensive overview of strategies and methodologies for reducing C−O and heteroatomic−oxygen bonds (N−O, S−O, P−O) using I2/I−, as well as other synthetically relevant bonds such as C−C, N−N, C−N, C−X, C−S. It highlights and discusses most of the mechanistic details provided by the original authors. Selected examples of other halides (Br and Cl) as reductants are also covered.