bluuebunny/crossref_metadata_2025 huggingface dataset:
The Process of Regenerative Heat Treatment of the Valve Chamber of the Steam Turbine
Authors: Wieczorska Agata
Published: October 2019

Steel castings are often used in the construction of valve chambers of steam turbines. Stringent requirements are set due to the continuous operation of the material at elevated temperatures, in the order of 300°C to 600°C. The material of the valve chamber must be resistant to fatigue-creep changes as well as corrosion. This material must be also resistant to dynamic damage which occures when the turbine is starting and stopping. Dynamic damage is induced by a short-lasting but intense accumulation of localized stresses. The castings of the valve chambers of the steam turbine are usually made from the “three-component” type CrMoV-cast steel. Mentioned castings of the valve chamber are continuously subjected to high temperatures, either constant and periodically variable stresses. Due to this, the degradation process of material of the castings is taking place. It is caused by physicochemical processes such as: creep, relaxation, thermal fatigue, corrosion, erosion and changes in material properties, e.g. displacement of the critical point of brittleness. Finally, first cracks and deformations can be observed in the material during the operation. The art presents the process of revitalization technology of the steam turbine valve chamber which was subjected to long-term operation at high temperatures. The revitalization process is aimed at improving the plastic properties of the material and, as the result, extending its service life. The research presented in the article show that impact strength of the chamber material after revitalization is very high. Also the strength properties of the valve chamber, after revitalization, are high and in line with the requirements. The study show that the revitalization of the valve chamber was carried out correctly and restored the material to plastic deformation.
Gyroplane Rotor Hubs Strength Tests
Authors: Wojtas Małgorzata , Sobieszek Agnieszka
Published: October 2019

In this article a review of rotor, hub constructions were presented. Discussed rotor’s hub is made of composite or aluminum alloys materials. Two types of rotor hub were presented (four-blades and two-blades teetering rotor hub), each of them are dedicated to gyroplanes. Typical gyroplane main rotors are characterized by simple design, especially in case of rotors for light gyroplanes. In the following part of the article the type of strength tests required by certification process were shown. The test programs based on legal aspects of admission to the flight tests taking into account legislation such as CS 27 (Subpart C – Strength Requirements), CAP 643 British Civil Airworthiness requirements Section T Light gyroplanes, ASTM F2972. Furthermore, this article discusses strength tests of gyroplane rotor hub such as measured parameters, methodology of measurement, types of sensors, course of test, test stands, and limit loads. The loads during “pull-up from level flight” manoeuvre are limit loads during tests. Required additional processes, like a verification the same parameters by two types of method were shown i.e. deformation of structure were tested by strain gauges and reverse engineering. Strength tests had to be made before flight test, based on results of them aircrafts are flight authorized. In conclusion, the results of tests were presented and fulfilment of legal assumptions and requirements were shown.
Turbulent Triggers and the Model Quality Influence on Aerodynamic Characteristics of the Laminar Aerofoil in Transonic Flow Regime
Authors: Placek Robert , Ruchała Paweł
Published: October 2019

The test with a roughness application on the laminar aerofoil has been conducted in the N-3 trisonic wind tunnel of the Institute of Aviation in Warsaw. The main goal of tests was to investigate the influence of the boundary layer transition triggers on a laminar profile aerodynamic characteristic. For baseline configuration, the natural transition was applied. As a local roughness on the upper model surface, the carborundum strips with different heights were applied. These were positioned on the upper model surface in the front of the shock position occurrence. The Mach number during test was equal Ma = 0.7 and Reynolds number was about 2.85·106. Tests have been conducted for different model incidence in range 0°-7°. Current article refers partially to the previous study, where aerofoil model with lower quality of surface had been tested. Investigation results from previous work indicated that some of transition positions improved an aerodynamic characteristic by reducing the drag coefficient value and decreasing shock wave unsteadiness in the transonic regime. However, current article indicates that beneficial effects in respect to the baseline configuration are also strictly dependent on the model quality and turbulent triggers size. Improved surface quality of the laminar aerofoil model affected on aerodynamic characteristics with and without turbulent triggers. Resultant aerodynamic coefficients of all tested cases i.e. drag, lift and lift to drag ratio were compared.
Influence of Honeycomb Core Stabilization on Composite Sandwich Structure Geometry
Authors: Michalski Mateusz , Krauze Wojciech
Published: October 2019

Authors showed the influence of stabilization of the honeycomb core on shape of the composite sandwich test panel. Adhesive film laid on core ramps and cured with suitable cure cycle served as core stabilizer. Test panel geometry included different ramp angles (20° and 30°). To verify stabilization process a technology trial was performed. Three test panels were manufactured (3-stage, 1-stage and 1-stage with stabilized core). All test panels were manufactured in OoA process (Out of Autoclave). Panel surfaces were scanned with 3D scanner and compared with the reference CAD model. Both outer skin and inner skin were manufactured in Automated Fiber Placement Laboratory of Warsaw Institute of Aviation.
Mathematical Models and Computer Simulations of Aerial Spraying and Droplets Distribution in a Target Site
Authors: Rowiński Robert S.
Published: October 2019

Mathematical models describing aerial spraying and the distribution of liquid droplets on a target were presented. Relationships based on “free models” with Gaussian distribution of droplet concentrations and “bound models” that account for the impact of disturbances in the velocity field behind agricultural aircraft were expanded, and the hybrid model too. The results of experimental studies were presented and compared with theoretical calculations. The “bound model” was found to be the most effective solution for describing the physical phenomena that accompany the aerial spraying process.
HUBUNGAN PEKERJAAN DAN SIKAP IBU MENYUSUI DENGAN PEMBERIAN ASI EKSKLUSIF PADA BAYI USIA 0-6 BULAN DI DESA LEBENG TIMUR KECAMATAN PASONGSONGAN
Authors: Oktavianisya Nelyta , Sumarni Sri
Published: October 2019

Breastfeeding is a natural process but often mothers fail to breastfeed more than theyshould. Lots of moms who choose not to give Exclusive Breast Milk. The problem of this research isthe low level of Exclusive Breastfeeding in Lebeng Timur Village Pasongsongan Sub-district by4.5% from the target of 90%. The aim of this research is to determine the relationship between jobsand mother attitude with giving of exclusive ASI in Lebeng Timur Village Pasongsongan SubDistrict.The design of this study is Cross Sectional Study. The sample sum a 40 nursing mothers whohave infants aged> 6-12 months taken using proportionate random sampling technique. The dataanalyzed using Chi- square test.The results showed that some of the respondents work (65%), had positive attitude (47,5%),and only (37,5%) respondents give exclusive breastfeeding. There is a relation between jobs(p=0.000) and the attitude of the breastfeeding mother (p=0,012) whit the exclusive breastfeeding.Mothers, particularly career mothers, are suggested to always give breast milk so that they couldpromote to the success of exclusive breastfeeding.
PSİKOLOJİK GÜÇLENDİRME-ÖRGÜTSEL ÖZDEŞLEŞME İLİŞKİSİ ÜZERİNE BİR SAHA ÇALIŞMASI
Authors: YILMAZ Cafer
Published: October 2019

Bu çalışmada psikolojik güçlendirme ve örgütsel özdeşleşme ilişkisi bir
yerel yönetim birimi çalışanları üzerinde incelenmiştir. Bu çerçevede bu iki
kavram arasındaki ilişki Gaziantep Büyükşehir Belediyesi çalışanlarından oluşan
4.458 kişilik evren içerisinden 555 kişilik bir örneklemle anket yapılarak
incelenmiştir. Araştırmada tabakalı örnekleme metodu kullanılmıştır. Yapılan
analizler sonucunda psikolojik güçlendirmenin örgütsel özdeşleşme üzerinde
olumlu etkisi olduğu belirlenmiştir. Ayrıca demografik ve bireysel özellikleri
de içeren alt hipotezler ile bağımlı ve bağımsız değişkenler arasında farklı
ilişkiler tespit edilmiştir. Bu sonuçlara göre, katılımcıların psikolojik
güçlendirme algıları ile eğitim düzeyi arasında anlamlı ve negatif bir ilişki
belirlenmiştir. Özdeşleşme algıları ile eğitim durumları arasında anlamlı ve
negatif, çalışma süreleri (kıdem) ile anlamlı ve pozitif ilişkiler
saptanmıştır. Öte yandan evli katılımcıların özdeşleşme algılarının bekâr
olanlara nazaran daha yüksek olduğu saptanmıştır.
Aspecto histopatológico do Carcinoma Adenoide Cístico em cavidade bucal: relato de caso
Authors: Dos Anjos Camilla Lins , Cavalcanti Laís Regina de Oliveira , Chagas Karla Alves , Sena Mycaelle Stephanny das Neves Barbosa , Peixoto Fernanda Braga , Ferreira Sonia Maria Soares , Panjwani Camila Maria Beder Ribeiro Girish
Published: October 2019

Objetivo: Relatar o caso clínico de Carcinoma Adenóide Cístico (CAC), mostrando características clínicas, histopatológicas e radiográficas da lesão. Detalhamento do caso: Paciente sexo feminino, 41 anos, compareceu ao serviço, com a queixa principal “vim por inchaço no dente”. Na história da doença atual, a paciente relatou que a lesão surgiu há aproximadamente dois anos, no palato duro, a lesão começou pequena, cresceu lentamente e no início apresentava dor. Ao exame intraoral, foi detectado, lesão nodular extensa. A hipótese diagnóstica foi de Adenoma Pleomórfico. Realizou-se biópsia incisional e foi diagnosticada com CAC de padrão histológico misto: sólido e cribriforme, sendo encaminhada ao serviço oncológico, onde a paciente segue em tratamento quimioterápico e radioterápico Considerações finais: CAC é um tumor maligno raro e incomum de glândulas salivares menores. Em geral a excisão cirúrgica é o tratamento de escolha e, a radioterapia adjuvante, pode melhorar a sobrevida dos pacientes. Vários fatores são considerados para o prognóstico do CAC, dentre eles o tipo histológico e estágio clínico da doença. Destaca-se a importância da realização de exames complementares para o correto diagnóstico.
O impacto da Psicomotricidade no tratamento de crianças com transtorno do Espectro Autista: revisão integrativa
Authors: Oliveira Érica Monteiro , Gonçalves Francisca Tatiana Dourado , Magalhães Marcio Marinho , Nascimento Helena Morgana Sousa do , Carvalho Izabel Cristina Vale de , Lemos Ana Valéria Lopes , Said Érika Castelo Branco , Cunha Maria de Jesus Martins de Andrade Silva , Araujo Zaira Arthemisa Mesquita , Conceição Pedro Wilson Ramos da , Oliveira Emanuel Monteiro , Limeira Lucas Gabriel Ribeiro , Silveira Carlos Alberto Sousa , Carneiro Murilo Simões
Published: October 2019

Objetivo: realizar uma revisão integrativa para identificar as contribuições da Psicomotricidade como uma técnica de fortalecimento do desenvolvimento psicomotor em crianças com autismo. Métodos: Trata-se de uma revisão integrativa de caráter bibliográfica exploratória e descritiva dos resultados apresentados. Foi realizada uma busca referente ao tema abordado em artigos publicados entre 2010 a 2018 em português e inglês. As bases de dados utilizadas foram “Scientific Electronic Library Online (SCIELO)”, “Medical Literature Analysis and Retrieval System Online (MEDLINE)” e “Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS)” Foram utilizados 9 artigos para este trabalho. Resultados: Estudos mostram que a Fisioterapia através dos princípios da contribuição da Psicomotricidade tem benefícios que permite que a criança constitui-se na principal via de expressão do seu mundo interno e externo, onde obteve a melhora da qualidade de vida das crianças com Transtorno do Espectro do Autismo (TEA), proporcionou benefícios positivos nos sistemas, motor, cognitivo, sensorial, no desenvolvimento do ritmo, esquema corporal, postura, equilíbrio, coordenação motora, estruturação espacial, orientação temporal e interação social. Conclusão: Através desta revisão foi possível perceber que a fisioterapia tem um papel satisfatório onde se pode observar a importância da utilização da psicomotricidade no desenvolvimento, pois contribuem para evolução e estabilidade no equilíbrio, coordenação motora, hábitos de vida e interação social das crianças com diagnóstico de transtorno do espectro autista.
Aplicação do Método de Avaliação 360º em Residentes Médicos de Ginecologia e Obstetrícia
Authors: Bastos Carla Alessandra Haber , Botelho Nara Macedo , Portella Márcia Bittar , Cristina Lisboa do Nascimento Camilla
Published: October 2019

Objetivo: Implementar a avaliação 360º no Programa de Residência Médica em Obstetrícia e Ginecologia de um Hospital de Referência em Obstétrica e Ginecologia, localizado em Belém-PA. Métodos: Pesquisa de caráter exploratório, descritivo, com abordagem quantitativa. Foi desenvolvida nos cenários reais de prática dos médicos residentes e abrangeu todos os setores da tocoginecologia de um hospital de referência em procedimentos obstétricos e ginecológicos, localizado em Belém/PA. Os residentes e preceptores receberam capacitação in loco para participação no estudo. Foi definido como instrumento de avaliação 4 questionários: o Mini Clinical Evaluation Exercise (Mini-CEx), o qual foi utilizado pelos preceptores, além de instrumentos avaliativos do American Board Internal Medicine, que foram utilizados na avaliação pelos pares, pacientes e autoavaliação. Resultados: Foi aplicado um quantitativo total de 92 questionários, sendo 4 tipos diferentes para cada residente, o qual foi possível observar durante uma consulta a sua autoavaliação, a avaliações dos pares, avaliação do preceptor e a avaliação da paciente. Conclusão: Espera-se que esse estudo possa contribuir para futuras possibilidades de ampliação do processo de avaliação dos residentes.
Arritmias cardíacas: Diagnósticos de Enfermagem baseados na Taxonomia da NANDA-I (2018-2020)
Authors: Szpalher Adriana Souza , Batalha Marianne Cardoso
Published: October 2019

Objetivo: identificar os diagnósticos de enfermagem ao portador de arritmia cardíaca para promoção do apoio na realização do Processo de enfermagem para estes indivíduos. Métodos: revisão integrativa no período de maio a julho de 2019 nas bases de dados BVS, PubMed, SciELO, CENTRAL, CAPES, ProQuest e Google Acadêmico. O processo de análise do artigo selecionado deu-se por meio da leitura exploratória e detalhada de títulos, resumos e dos resultados das pesquisas, onde se buscaram os diagnósticos de enfermagem relacionados às arritmias. Resultados: Diagnósticos de Enfermagem identificados foram dor aguda relacionado a agentes lesivos biológicos e físicos evidenciado no relato verbal de dor e expressão facial; Insônia relacionado à ingestão de estimulantes ou álcool evidenciado com limitação do padrão normal do sono e por dificuldade de ordenar ou manter o sono; Estilo de vida sedentário relacionado a falta de motivação e de interesse evidenciado pela falta de condicionamento físico. Considerações finais: por haver escassa produção de estudos relacionados ao objetivo, sugerem-se estudos que desenvolvam o Processo de Enfermagem ao portador de arritmias nos contextos intra e extra-hospitalar. Ainda se sugere a investigação de diagnósticos em outros domínios que não foram abordados, visando, assim, a atuação de forma holística.
Abordagem cirúrgica de fechamento de fístula buco-sinusal pela técnica do retalho vestibular: relato de caso
Authors: Dos Anjos Flayane Nuberly Farias Gomes , De Melo Maria Carolina Gaia , Leite Ingrid Ferreira , De Melo Diana Pimentel , Lucas Luciano de Almeida , De Macedo Lucas Fortes Cavalcanti , Cavalcanti Tayguara Cerqueira
Published: October 2019

Objetivo: Elucidar acerca da abordagem cirúrgica do fechamento de fístula buco-sinusal pela técnica de retalho vestibular, bem como, esclarecer ao Cirurgião-dentista os principais fatores relacionados ao surgimento desta complicação. Estudo de Caso: Relata-se o caso de um paciente, gênero feminino, 40 anos, que procurou atendimento afirmando “quando estou comendo, a comida sai pelo meu nariz”. Durante a anamnese a paciente informou que há 3 anos foi submetida a exodontia do elemento 26 e que desde então percebeu a passagem de líquidos e alimentos da cavidade oral para a cavidade nasal. Ao exame clínico foi observado um defeito do rebordo alveolar como possível tentativa de reparo fisiológico. Levantou-se a hipótese diagnóstica de fístula buco-sinusal após exodontia do elemento 26, foi solicitado uma radiografia panorâmica que evidenciou uma descontinuidade da radiopacidade do assoalho do seio maxilar. A resolutividade do caso se deu a partir da prescrição de profilaxia antibiótica e tratamento cirúrgico para fechamento da fístula buco-sinusal pela técnica de retalho vestibular. Paciente encontra-se em acompanhamento odontológico há 3 meses e até o presente momento não apresentou recidivas. Considerações finais: As fístulas buco-sinusais são complicações que podem e devem ser evitadas pelo Cirurgião-dentista através de um planejamento e avaliação detalhada do paciente.
Perfil epidemiológico do câncer infantil na Paraíba
Authors: Oliveira Aline Tavares de , Sousa Milena Nunes Alves de , Maia Paula Christianne Gomes Gouveia Souto , Bezerra André Luiz Dantas , Moura Beatriz Coelho Pires de , Santos Everson Vagner de Lucena , Trigueiro Gildenia Pinto dos Santos , Nogueira Tiago Bezerra de Sá de Sousa , Nogueira Raquel Bezerra de Sá de Sousa , Toledo Miguel Aquila , Mazzaro Vandezita Dantas de Medeiros , Suárez Larissa de Araújo Batista , Custodio Patrícia Peixoto , Egypto Ilana Andrade Santos do
Published: October 2019

Objetivo: Analisar o perfil epidemiológico do câncer infantil na Paraíba. Métodos: A investigação foi realizada mediante estudo documental, descritivo, transversal, com abordagem quantitativa. A coleta dos dados foi feita a partir das informações disponíveis na internet, no sitio do Instituto Nacional do Câncer. O instrumento utilizado para coleta de dados foi uma ficha contendo tipo de neoplasia, sexo e faixa etária mais acometida. Tais dados foram compilados no Microsoft Excel e sua análise foi efetivada mediante estatística descritiva. Resultados: Os achados indicaram que o tipo de câncer mais incidente nas crianças paraibanas, independente do sexo e com idade acima de um ano, corresponde às leucemias que são classificadas como grupo I; os do sistema nervoso central, grupo III e os linfomas, grupo II, respectivamente. Em relação ao grupo menor de um ano, observou-se que houve uma prevalência maior no sexo feminino nos grupos I, II, V, VI e IX, enquanto que no sexo masculino a maior prevalência foi encontrada no grupo III. Entretanto, é válido ressaltar que em relação ao grupo I, apesar de maior prevalência no sexo feminino, o grupo masculino também possui um valor considerável, com uma pequena diferença entre eles. Conclusão: A incidência dos mais variados tipos de tumores na população pediátrica é diferente em relação à faixa etária e ao sexo, tornando seu perfil epidemiológico bastante diversificado.
A atuação do cirurgião dentista no âmbito hospitalar: Uma revisão de literatura
Authors: Silva Neto José Milton de Aquino e , Araújo Filho Paulo César Agra , Cavalcante Cleber Rodrigues , Almeida Barros João Vitor Brasil Alves Rodrigues , Oliveira Daysielle Rodrigues de , Tenório Neto João Francisco
Published: October 2019

Objetivo: Analisar o papel do Cirurgião Dentista (CD) no âmbito hospitalar, que tem demonstrado relevante importância na conjuntura multidisciplinar de saúde, tendo em vista a melhora dos pacientes. Apesar disso, sua participação nas Unidades de Terapia Intensiva (UTI) apresenta grande carência, mesmo compreendendo que é indispensável a higienização bucal para evitar problemas da cavidade oral. Métodos: tratou-se de uma revisão de literatura, com abordagem descritiva e informativa, em que o processo de formulação se deu através de buscas por literaturas cientificas, em bases de dados, tendo como descritores: Odontologia Hospitalar, melhoramento da evolução do paciente internado relacionado aos cuidados da cavidade oral. Resultados: O CD no âmbito hospitalar desempenha o papel da integralidade visando a promoção da saúde bucal em pacientes hospitalizados evitando a piora das enfermidades devido à má higienização oral. Considerações Finais: O CD está se especializando e se qualificando nas intervenções reabilitadoras de pacientes internados, com o propósito de minimizar focos de infecções do meio bucal, dispondo de procedimentos periodontais, restauradores, cirúrgicos. Diminuindo com isso o tempo de internação dos pacientes por causa da redução das possíveis infecções relacionadas ao meio oral.
Intermittent penile erection in lumbar spinal stenosis: Report of four new cases and review
Authors: Rahimizadeh Abolfazl , Soufiani Housain , Williamson Walter L. , Rahimizadeh Shaghayegh , Amirzadeh Mahan , Karimi Mona
Published: October 2019

Background:

Lumbar spinal stenosis (LSS) classically presents with intermittent neurogenic claudication. Rarely, however, it may cause unanticipated, unpleasant, involuntary, and transient penile erections without sexual stimulation along with urinary urgency and claudication.

Case Description:

The authors present four males with LSS whose principal symptoms were intermittent neurogenic claudication and unanticipated erections while walking, accompanied by urinary urgency.

Conclusion:

There is scant literature on the topic of LSS presenting with unanticipated penile erections, urinary urgency, and neurogenic claudication.
In Silico Druggability Assessment of the NUDIX Hydrolase Protein Family as a Workflow for Target Prioritization
Authors: Michel Maurice , Homan Evert J. , Wiita Elisee , Pedersen Kia , Almlöf Ingrid , Gustavsson Anna-Lena , Lundbäck Thomas , Helleday Thomas , Berglund Ulrika Warpman
Published: October 2019

Computational chemistry has now been widely accepted as a useful tool for shortening lead times in early drug discovery. When selecting new potential drug targets, it is important to assess the likelihood of finding suitable starting points for lead generation before pursuing costly high-throughput screening campaigns. By exploiting available high-resolution crystal structures, an in silico druggability assessment can facilitate the decision of whether, and in cases where several protein family members exist, which of these to pursue experimentally. Many of the algorithms and software suites commonly applied for in silico druggability assessment are complex, technically challenging and not always user-friendly. Here we applied the intuitive open access servers of DoGSite, FTMap and CryptoSite to comprehensively predict ligand binding pockets, druggability scores and conformationally active regions of the NUDIX protein family. In parallel we analyzed potential ligand binding sites, their druggability and hydrophobic-hydrophilic ratio using Schrödinger’s SiteMap. Then an in silico docking cascade of a subset of the ZINC FragNow library using the Glide docking program was performed to assess identified pockets for large-scale small molecule binding. Subsequently, this initial dual ranking of druggable sites within the NUDIX protein family was benchmarked against experimental hit rates obtained both in-house and by others from traditional biochemical and fragment screening campaigns. The observed correlation suggests that the presented user-friendly workflow of a dual parallel in silico druggability assessment is applicable as a standalone method for decision on target prioritization in future screening campaigns.
Large Scale Indium Tin Oxide (ITO) One Dimensional Gratings for Ultrafast Signal Modulation in the Visible
Authors: Guizzardi Michele , Bonfadini Silvio , Moscardi Liliana , Kriegel Ilka , Scotognella Francesco , Criante Luigino
Published: October 2019

We present a photophysical study on an indium tin oxide (ITO) one dimensional grating, realized using femtosecond micromachining technology, a technology very industrially accessible. The geometries, dimensions and pitch of the various gratings analyzed are obtained by means of direct ablation in a controlled atmosphere of a homogeneous thin layer of ITO deposited on a glass substrate. The pitch has been selected in order to obtain a higher order of the photonic band gap in the visible. By means of ultrafast pump-probe spectroscopy we characterize both the plasmon and inter-band temporal dynamics. We observe a large optical non-linearity of ITO grating in the visible range, where the photonic band gap occurs, when pumped at the surface plasmon resonance in the near infrared (1500 nm). All together we show the possibility of all-optical signal modulation with heavily doped semiconductors in their transparency window with a picosecond response time through the formation of ITO grating structures.
Sequential Immobilization of Ansa-Hafnocene Complexes for Propene Polymerization
Authors: Arz Marius , Kratky Tim , Günther Sebastian , Rodewald Katia , Burger Thomas , Heuberger Manfred , Rieger Bernhard
Published: October 2019

We report the immobilization of the ultrarigid ansa-hafnocene complexes [Me2Si(Ind*)2HfCl2] (Ind* = 7,(3',5'-Di-tert-butylphenyl)-4-methoxy-2-methylindenyl) on silica as heteregeneous catalysts for propene polymerization. A sequential three-step synthesis on the siliceous surface led to pre-catalysts of the generalized structure SiO2-Si(Ind*)2HfCl2, which possess the silylene bridge of the substituted bis(indenyl) ligand directly attached to the surface. The immobilized pre-catalysts show very poor performance in the polymerization of propene, independent on the reaction conditions and the employed silica. Based on the results, we suggest that the close proximity of the catalyst to the surface combined with the steric congestion provoked by the ligand prevents a continuous polymerization, most likely due to a blockage of the catalytically active sites with growing polymer.
Identifying the Molecular Edge Termination of Exfoliated Hexagonal Boron Nitride Nanosheets with Solid-State NMR Spectroscopy and Plane-Wave DFT Calculations
Authors: Dorn Rick W. , Ryan Matthew J. , Kim Tae-Hoon , Goh Tian Wei , Heintz Patrick M. , Zhou Lin , Huang Wenyu , Rossini Aaron
Published: October 2019

Hexagonal boron nitride nanosheets (h-BNNS), the isoelectric analog to graphene, have received much attention over the past decade due to their high thermal oxidative resistance, high bandgap, catalytic activity and low cost. The molecular functional groups that terminate boron and nitrogen zigzag and/or armchair edges directly affect their chemical, physical and electronic properties. However, an understanding of the exact molecular edge termination present in h-BNNS is lacking. Here, high-resolution magic-angle spinning (MAS) solid-state NMR (SSNMR) spectroscopy and plane-wave density-functional theory (DFT) calculations are used to determine the exact molecular edge termination in exfoliated h-BNNS. 1H→11B cross-polarization MAS (CPMAS) SSNMR spectra of h-BNNS revealed multiple hydroxyl/oxygen coordinate boron edge sites that were not detectable in direct excitation experiments. A dynamic nuclear polarization (DNP)-enhanced 1H→15N CPMAS spectrum of h-BNNS displayed four distinct 15N resonances while a 2D 1H{14N} dipolar-HMQC spectrum revealed three distinct 14N environments. Plane-wave DFT calculations were used to construct model edge structures and predict the corresponding 11B, 14N and 15N SSNMR spectra. Comparison of the experimental and predicted SSNMR spectra confirms that zigzag and armchair edges with both amine and boron hydroxide/oxide termination are present. The detailed characterization of h-BNNS molecular edge termination will provide usefulness for many material science applications and the techniques outlined here should be applicable to comprehensively understand the molecular edge terminations in other 2D materials.
Fragment Pose Prediction Using Non-Equilibrium Candidate Monte Carlo and Molecular Dynamics Simulations
Authors: Lim Nathan M. , Osato Meghan , Warren Gregory L. , Mobley David L.
Published: October 2019

Part of early stage drug discovery involves determining how molecules may bind to the target protein. Through understanding where and how molecules bind, chemists can begin to build ideas on how to design improvements to increase binding affinities. In this retrospective study, we compare how computational approaches like docking, molecular dynamics (MD) simulations, and a non-equilibrium candidate Monte Carlo (NCMC) based method (NCMC+MD) perform in predicting binding modes for a set of 12 fragment-like molecules which bind to soluble epoxide hydrolase. We evaluate each method's effectiveness in identifying the dominant binding mode and finding any additional binding modes (if any). Then, we compare our predicted binding modes to experimentally obtained X-ray crystal structures.We dock each of the 12 small molecules into the apo-protein crystal structure and then run simulations up to 1 microsecond each. Small and fragment-like molecules likely have smaller energy barriers separating different binding modes by virtue of relatively fewer and weaker interactions relative to drug-like molecules, and thus likely undergo more rapid binding mode transitions. We expect, thus, to see more rapid transitions betweeen binding modes in our study.

Following this, we build Markov State Models (MSM) to define our stable ligand binding modes. We investigate if adequate sampling of ligand binding modes and transitions between them can occur at the microsecond timescale using traditional MD or a hybrid NCMC+MD simulation approach. Our findings suggest that even with small fragment-like molecules, we fail to sample all the crystallographic binding modes using microsecond MD simulations, but using NCMC+MD we have better success in sampling the crystal structure while obtaining the correct populations.
Treatment of Fractures in Black Africa: The Current State of Play
Authors: Packo Dieu-le-Veut Saint-cyr Sylvestre  , Feigoudozoui Hermann Victoire
Published: October 2019

Editorial Comment by Dr. Packo Dieu-le-veut Saint-Cyr Sylvestre, Member, International Editorial Board, IHRJ and Dr. Feigoudozoui Hermann Victoire
Public policy of GST in India: A study on pharmaceutical sector with special reference to Healthcare
Authors: Arun Gautam  , Shivani Kampani  , Gaurav Lodha  , Vadera M L
Published: October 2019

India's greatest duty move is now a reality. 1999 was the year when GST was thought of. The amending bill for the full-powered launch of GST was approved by the Rajya Sabha on 8 August 2016, and it was enacted in late August. It is essential to comprehend that GST isn't a duty concession scheme where every good and service has become way cheaper just because the administration has decreased the duty rates. The single Revenue Neutral Rate (RNR) was a difficult system to manage, and thus the Indian govt. I wanted to fix it. Nonetheless, because of practical reasons, "four GST slabs have been set at 5%, 12%, 18%, and 28%. Precious metals have a special rate. The rate of 18% would anyway be relevant for most goods. GST was enacted on 1 July 2017."
欧盟偿付能力Ⅱ下的保险公司信用风险分析——基于 KMV 模型
Authors: 王 颖
Published: October 2019

欧盟偿付能力Ⅱ实施的重要目的就是建立一个科学的偿付能力框架来实施高效的保险公司偿付能力管理，以提升欧洲保险监管效率。在欧盟偿付能力Ⅱ体系下，对于资本需求的计算提供了一种新型的模型——即内部模型。那么在这种新型的模型下，对于信用风险的矫正的准确性是否充分，将是本文的研究目的。本文将比较研究这种新型的资本需求计算方式，通过 KMV模型来预估保险公司的预期违约率，以期能得出在欧盟偿付能力Ⅱ下所使用的内部模型的有效性。
高频金融时间序列的统计特征
Authors: 叶 建萍 , 卢 月莉
Published: October 2019

经济社会的快速发展，对各领域的发展都产生了巨大的影响，而在金融市场的发展中，逐渐地出现了高频金融，其时间序列具有独特的统计特征，与传统的金融理论相比较，其自身存在着不一致的异常现象。针对其自身独特的性质分析，还需要结合其实际发展的具体情况为基础，重视其新模型，能够实现对信息数据的生成与转换，观察其转换的具体过程，为众多的投资者提供了重要的信息依据，确保做出的决策具有科学性、合理性，对具体的生产发展进行了明确的原因解释。对此，本文主要对高频金融时间序列的统计特征进行了分析，通过对其建模的分析，为其奠定了一定的理论基础。
Strategies of Ideological and Political Education Transformation for Vocational College Students in the Internet Micromedia Era
Authors: Yang Bin
Published: October 2019

Due to the continuous development of science and technology, Chinahas stepped into the stage of rapid development of network information technology. Internet technology products come out in an unending ﬂow, such as tablets and mobile phones, which are representative. In order to meet the needs of economic and social development, “micromedia” has become the mainstream of current social development, including: QQ, WeChat, Tik Tok and Weibo, which have become indispensable platforms for people to get information and communicate with each other in daily life. We have ushered in the “micromedia era”. On the one hand, it has injected new impetus into China’s social economy; on the other hand, it has opened up a new horizon for China’s education. The focus and diffculty of this paper is how to effectively combine the teaching ideas of vocational colleges with “micromedia” and elaborate its transformation strategy and policy.
La Ética como medio para la vida buena: Una reflexión desde A. MacIntyre
Authors: Izquierdo David Lorenzo
Published: October 2019

En la actualidad, la ética está excesivamente centrada en la reflexión y en el establecimiento de reglas, de normas. Muchos debates sobre ética empiezan o acaban en la reflexión sobre qué normas o reglas deben aceptarse pública o universalmente, sobre cuáles de ellas deben ser leyes civiles, sobre qué comportamientos la ley civil debería prohibir y por qué. A juicio del autor, este hecho supone un reduccionismo y hace olvidar que lo más importante de la ética es el desarrollo integral del individuo. Las reglas tienen su importancia en ética, pero no son el factor más relevante en ella porque no son suficientes para ayudar al individuo al desarrollo de sus capacidades, para su vida buena. El artículo muestra cómo la virtud juega un papel fundamental en ese proceso.
PR COMMUNICATIONS OF PUBLISHING HOUSES AS A SCIENTIFIC OBJECT
Authors: Jezhyzhanska Tetyana
Published: October 2019

The article studies the current state and prospects of researches of
publishing house’s communications, namely PR communications of book publishers. The attention is drawn to insufficient scientific development of this problem, on t one hand, and obvious importance in the modern conditions to provide publishing house with competitiveness, on the other one. The literature and sources related to this issues are analyzed, the theoretical and practical possibilities of using PR in the activity of book publishers are determined, the history and current state of research of publishing house`s PR communications is studied. The prospects for further scientific study and practical use of PR communications in the activities of publishing houses are determined. The relevance of the research topic is that communication in the information society is a fundamentally new phenomenon that creates new values, changes the technologies and product configurations, systems of work with the clients. The companies have always tried to establish communication, that is built around and within the system of interactions, which would help managers to achieve a strategic goal. However, the modern communications are different from traditional ones. The objective of the article is to investigate formation of theoretical basis of PR-communications of publishing houses in the modern media space of Ukraine. The realization of this objective involves performing the following research tasks: to analyze the professional literature on the main issues of research; to find out the positions of foreign and domestic communications researchers in the publishing industry; to consider the theoretical studies of PR communications of publishing houses in the modern media space. To achieve this objective, we use such general scientific methods as analysis that allowed us to separate the actual tendencies of communication in publishing industry for their subject study, synthesis, by which the integral picture of theoretical basis of the research of communications of publishing industry of Ukraine is integrated into the whole. The method of generalization allowed to study, to systematize and to structure the information. Also, the descriptive method and method of comparison were used, as well as with the help of the method of scientific forecasting we were able to determine the prospects of development of PR- communications of publishing houses in the modern media space
Pengembangan Konsep Kompensasi Dosen dengan mekanisme reward/punishment ditopang dengan konsep sustainabilitas keuangan dengan menggunakan Sistem Informasi. (Studi Kasus : Universitas X)
Authors: Imbar Radiant Victor
Published: October 2019

The performance of X University in addition to being measured by academic productivity, is also measured by the competence of academic staff. Career development, productivity and performance of X University employees (especially lecturers) is the key to X University development strategies towards 2034. So there is a need to build a fix take home pay compensation concept solution with a more valid concept, more effective as a reward / punishment mechanism, and supported by concepts financial sustainability. In addition, the concept must be implemented to an information system that supports fix take home pay compensation to enter lecturer work plans and provides reports on the results of lecturer achievements each semester.
Optimalisasi Distribusi Harga Tiket Pesawat berdasarkan Kepadatan Rute Menggunakan Algoritma Genetika
Authors: Novianti Sri Hutamy , Djamal Esmeralda C. , Komarudin Agus
Published: October 2019

The development of the aviation industry in Indonesia in the past decade has risen sharply. One of the impacts of the development of the aviation industry was the presence of a multilevel tariff concept. Where, the concept is the variation in ticket prices in one class with slightly different facilities such as the difference in penalty fees for making refunds and rebooking. The concept of multilevel rates is usually referred to as sub-class rates. One application of the sub-class tariffs in economic classes is divided into four types of sub-classes special promo sub-classes, promo sub-classes, then affordable sub-class and flexible sub-class. One optimization method of getting a combination that meets the requirements without having to try all possibilities is the Genetic Algorithm. The chromosomes built represent 10 subclasses on 9 routes so that they have 90 genes. The use of genetic algorithms originated from the generation of an initial population of 8 chromosomes with a length of 90 genes performed randomly, evaluation of the compatibility function was then selected using the Rank based fitness technique, crosses using Multi-Point Crossover, mutations with the Mutation Insertion technique. The system built was tested with two conditions each of eight tests with 100 generations. First, the test uses the mutation method of three subclass codes on four routes at a capacity of 150 seats, obtained the largest match value of Rp. 750,752,200 and the smallest Rp. 662,283,100. And testing with the mutation method of three subclass codes on eight routes of 150 seat capacity obtained the largest match value of Rp. 763,265,300 and the smallest Rp. 547,396,200. The results of testing the mutation method on eight routes resulted in a higher match value compared to the mutation method on four routes. The system has been implemented in software so that it can provide recommendations on the number of ticket passes distributed in the economic subclass.
Understanding the role of ICT in South African Sustainable Manufacturing Practice
Authors: Alhassan Mohammed , Scholtz Brenda
Published: October 2019

Existing literature perceived Economic, Social and Environmental (ESE) factors as three key drivers of Sustainable Manufacturing Practice (SMP). ICT is not considered as a driving factor, but only as a tool that supports the achievement of SMP. The aim of this study is to investigate the role of ICT in achieving SMP in South Africa. A systematic literature review was conducted. The Google Scholar search engine was used to retrieve 1,352 articles that were analysed in this study. Themes and constructs were analysed based on the scope of the study. The findings revealed that South African manufacturing stakeholders are leveraging the advancement of ICT such as Artificial Intelligence and smart production systems to drive SMP through reduced waste and optimisation of resources. Also, the findings revealed that ICT plays a significant role that warrant its consideration as a fourth factor that drives SMP. This study emphasised the role of ICT as a driver in achieving SMP and presents the ESET model (ESE with the addition of Technology) to support the argument that ICT is a major driving factor for SMP. Understanding the role of ICT can influence how the issues of SMP are addressed and stakeholders can rethink strategies for SMP. Further empirical studies with a broader scope are encouraged because the review process and the scope of this study limits its generalisability
Attitudes of Belgian Companies towards Outsourcing Microwork to Africa
Authors: Van Belle Jean-Paul , Bonne Karijn , Cocquyt Ilse , Garbutt Malcolm
Published: October 2019

This research investigates the attitude of Belgian companies to outsource microwork to Africa. Microwork has the potential of alleviating high youth unemployment in Africa and simultaneously improving African digital economies. The purpose of this research is to find out whether overseas companies are already making use of micro job outsourcing, which platforms are used for this, which jobs are being outsourced and whether there is interest in those companies that still do not use micro work. The research also discusses the barriers that prevent companies to outsource microwork to Africa. 196 companies in Flanders (Belgium) were surveyed using a questionnaire. Five recommendations are presented, based on the perceived barriers and issues, to entice them to start or increase outsourcing micro-work to Africa.
A conceptual framework for a student personal information privacy culture at universities in Zimbabwe
Authors: Maguraushe Kudakwashe , Da Veiga Adele , Martins Nico
Published: October 2019

In this research, an information privacy culture is proposed to be embedded in three basic concepts: students’ privacy expectations, privacy awareness and confidence in universities’ capability to uphold information privacy. The aim of this research was to address the lack of an information privacy culture framework in the context of universities in Zimbabwe, the upsurge of privacy breaches in these institutions and the need to assist them in processing the information in line with regulatory requirements. The main objective of this study was therefore to ascertain the key components of a student personal information privacy culture (SPIPC) conceptual framework for universities in Zimbabwe. A scoping review was conducted and a SPIPC conceptual framework is proposed.
A IDENTIDADE DO PROFESSOR TUTOR
Authors: Muniz Anne Caroline Campos , Oliveira Antônio Heribaldo
Published: October 2019

Este estudo objetiva destacar a ação tutorial do professor quando desempenhando suas funções na Educação a Distância - EAD, explicitando as competências e atribuições que lhes são necessárias. Aqui citaremos parte de estudos teóricos já existentes delineando embasamentos teóricos sobre a profissão de tutor, inserido num plano de educação continuada, destacando as habilidades e formação dos tutores, analisando suas particularidades e implicações, apontando possibilidades, no desenvolvimento dos acadêmicos de um modo geral e com bastante ênfase frente a estes que iniciam sua vida acadêmica nas diversas instituições de ensino superior à distância. No desenvolvimento deste trabalho utilizou-se o método bibliográfico do tipo explicativo, fazendo uso do estudo empírico, com abordagem qualitativa. O estudo demonstra a importância de pesquisar a identidade do professor tutor na modalidade EAD, a fim de destacar a formação intelectual e social desse profissional atuante no cenário educacional em constante crescimento no país.   Palavras-chave: Professor-Tutor. Identidade. Competências
DOCÊNCIA E TECNOLOGIA: UMA EXPERIÊNCIA COM PROFESSORES EM INTERAÇÃO COM OBJETOS TÉCNICOS
Authors: Chagas Maria de Fátima de lima das , Demoly Karla Rosane do Amaral
Published: October 2019

Foi investigado como um grupo de 15 professores do ensino fundamental da rede pública municipal de Mossoró (RN) experimentou processos de produção do conhecimento sobre tecnologias em um percurso onde foram convidados a uma reflexão sobre como as tecnologias digitais configuram modos de viver e de conhecer. A análise da experiência contou com o aporte teórico de Gilbert Simondon, Humberto Maturana e Francisco Varela, dentre outros que discutem a relação humano-máquina e os processos de conhecimento. Enquanto pesquisa intervenção, foi organizada a partir de oficinas propostas em que os professores interagiram com objetos técnicos, realizaram diferentes produções relacionadas às suas demandas singulares e às atividades pedagógicas e, ao mesmo tempo, encontraram espaços de escrita digital para conversar sobre a experiência. Como resultados, consideramos que o encontro de professores com tecnologias digitais em uma proposição onde podem conversar sobre a experiência em rede favoreceu práticas de exercício de autoria e mudanças na forma de conceber a presença das tecnologias nos fazeres pedagógicos. Palavras-chave: Tecnologia. Objetos técnicos. Percurso de professores.
ENSINAR E APRENDER A DISTÂNCIA: QUE MAIS IMPORTA?
Authors: Romão Eliana Sampaio , Nunes Cesar Aparecido
Published: October 2019

Ensinar para que o outro aprenda não é em nada simples. Muitos são os desafios. Em ambientes não convencionais de educação os desafios se multiplicam. Se já é difícil manter uma relação de ensino e aprendizagem numa dimensão de proximidade, o que se dirá de longe, à distância. Nesse contexto, promover a comunicação e envolver aluno(a) continua a inquietar os protagonistas desse processo. Indaga-se, então, o que mais importa para que a distância não seja um fardo e para que o encontro seja um diálogo orgânico e possível? Nesse cenário, o presente artigo objetiva, a partir de estudo bibliográfico, mostrar o que mais importa para que a comunicação seja assegurada e a educação prevaleça. Fazer bom uso das tecnologias digitais importa, e muito.  Mas se valer desta prática não basta para revigorar uma didática cansada, alunos desinteressados e fazer prevalecer a educação. Palavras chave: Educação a distância. Professor. Comunicação. Tecnologias educativas.