bluuebunny/crossref_metadata_2025 huggingface dataset:
Aporte de las revistas científicas colombianas de teología y filosofía en la difusión de investigaciones sobre corrupción, paz y reconciliación a partir de un estudio bibliométrico
Authors: Acuña Flor Alba , Sánchez Magle Virginia
Published: May 2019

El objetivo del presente artículo fue identificar el aporte de las revistas científicas colombianas de teología y filosofía en la difusión de investigaciones relacionadas con los temas de corrupción, paz y reconciliación, por medio de un estudio bibliométrico centrado en indicadores de impacto con el propósito de generar reflexiones. El método se centró en un estudio cuantitativo no experimental, siguiendo el método de revisión sistemática. En Colombia, existen nueve revistas científicas en el área de teología y filosofía indexadas en Publindex; el 11,1 % está en categoría A2, el 22,2 % en B y el 66,7 % en C. En cuanto a la posición en SJR, el 22,2 % está en los cuartiles medios (Q2 y Q3), el 33,3 % en Q4 y el 44,4 % sin cuartil. Respecto a la difusión relacionada con los temas de corrupción, paz y reconciliación, el aporte es muy bajo: 3,4 % y 2,7 % respectivamente. La baja visibilidad de estas publicaciones plantea la necesidad de evaluar el cumplimiento de gestión editorial y calidad de contenido, que afectan la divulgación de los resultados de investigación, pero también se debe tener en cuenta las características y dinámicas propias de las publicaciones en humanidades.Palabras clave: corrupción, paz y reconciliación, factores de impacto, análisis de contenido, teología, filosofía. Contribution of the Colombian Scientific Journals of Theology and Philosophy in the Dissemination of Research on Corruption, Peace and Reconciliation Based on a Bibliometric StudyAbstractThe objective of this article is to identify the contribution of scientific journals of Theology and Philosophy to the dissemination of research related to corruption, peace and reconciliation issues, through a bibliometric study focused on quality criteria with the purpose of generate reflections. The method focusing on a non-experimental quantitative study, following the method of systematic review. In Colombia, there are 11 scientific journals in the area of Theology and Philosophy indexed in IBN-Publindex, 11.1 % are in category A2, 22.2 % in B, and 66.7 % in C. Regarding the position in SJR, 22.2 % are in the middle quartiles (Q2 and Q3), 33.3 % in Q4 and 44.4 % without quartile. With respect to corruption, peace and reconciliation, the contribution is very low, 3.4 % and 2.7 % respectively. The low visibility of these publications. Information. Information. The publications. The answers. Humanities.Keywords: Corruption, peace and reconciliation, quality, content analysis, Theology, Philosophy.
The Syntactic Means of Smallness NotionRepresentation in Ukrainian, English and Latin Languages
Authors: Ruda N.
Published: May 2019

In the article the structure, semantics and functions of syntactic means of the smallness notion representation in Ukrainian, English and Latin languages are compared and analyzed. Common and particular for each language semantic-functional characteristics of analytical diminutive units are identified. The ability of syntactic means to express the full range of meanings associated with the notion of smallness is highlighted. The category of smallness (diminutiveness, diminution) is postulated in the article as a general gnoseological-linguistic category. The category of smallness usually denotes the small size of the object or the weakened manifestation of a feature or action, but very often the noted meanings can be accompanied by different evaluative-emotional and expressive semes. In different languages the smallness notion can be represented by means of different levels of the language structure, whose role in each language is certainly not the same. As we know, Ukrainian and Latin are synthetic languages, which explains the priority in expressing the notion of smallness by means of suffixation, while English as an analytical language has a smaller amount and productivity of diminutive suffixes, what is compensated by syntactic means. The study found out that in Ukrainian and Latin languages the diminutive phrases express mainly the meaning of real smallness, but in English the using of syntactic means in accordance with the needs of the native speakers compensates the lack of both suffixal diminutives of objective smallness semantics and suffixal diminutives of evaluative-emotional and expressive meaning.
Derivatization of the Word-forming Model “OWN-ALIEN”in the Japanese Language against the Background of Historical Dynamics of theJapanese Writing System Forms Development: Diachronic and Syncronic Aspects
Authors: Pyrogov V.
Published: May 2019

The paper attempts to study the conditions of historical origin and subsequent derivatization of the basic word-formation model “own-alien” in the Japanese language against the background of historical dynamics of the Japanese writing system development. Despite the fact that Japan and the Japanese are considered genetically isolated from the rest of the world, they repeatedly had to face the influence of external factors, in particular, to perceive and assimilate the norms and stereotypes of foreign cultures and languages, while preserving their national identity and integrity, and at the same time, to improve their own language and culture, resulting in the formation of a highly original and unique language that can be characterized as syncretic – Japanese-Chinese – with inclusion at present time of lexical elements from European languages, mainly English. The Japanese pattern of thinking has been periodically restructured throughout the history of the formation and development of their civilization. And every time at the moment of cardinal transformation of their culture one of the important if not the main factor was writing system, which served as a special mean of adjusting their culture and mentality. In recent decades, the algorithm of Japanese thinking has changed, adapting to the conditions of a new historical format (which corresponds to the synchronous type of thinking), while the Japanese writing largely preserves the traditional form, which corresponds mainly to the archaic type of thinking. As a result, objective cultural and psychological contradictions arise, and at the same time a need to find a way out of this difficult situation emerges, perhaps by further reforming the existing system of writing, creating a more adequate system of written signs that would correspond to the imperatives of the modern socio-cultural paradigm.
FORMATION OF INVESTMENT PORTFOLIO
Authors: Dmitriev D. N. , Tikhonova M. V.
Published: May 2019

The article is devoted to analytical research in the field of the formation of the investment portfolio, based on the goals that investors set themselves. In the course of the study, the basic points of forming your own investment portfolio were considered on the basis of various profitable assets existing on the Russian market, such as stocks, bonds, mutual funds, investments in forex, trust management and high-risk investments. In addition, approaches to the formation of an investment portfolio were analyzed on the basis of targets, the investor’s financial capabilities, estimated incomes and acceptable risk levels.
Reliability of cardiovascular drug use in pregnancy with clinical pharmacology teratology risk analysis
Authors: Altıntaş Aykan Duygun , Ergün Yusuf
Published: May 2019

Purpose: Maternal cardiac disease is one of the major causes of non-obstetric maternal morbidity and mortality. In the treatment of cardiovascular diseases during pregnancy, it is important to prescribe the drugs that control maternal disease and to minimize potential drug-related risk to the fetus. The aim of this study is to evaluate the teratogenic safety of cardiovascular drugs in pregnancy.Materials and Methods: We collected data of pregnant women who used drugs for cardiovascular disorders and admitted to our unit for drug analysis between 2014 and 2018. Teratology Information Service assessed the teratogenic risk of drugs. After delivery, a follow-up was conducted with families to obtain the presence of any congenital malformations or adverse neurodevelopmental effects in the infant. Results: Use of ramipril in the first six weeks of pregnancy resulted in spontaneous abortus at the 10th week. Use of warfarin in the first 12 weeks resulted in exitus at the postnatal fourth day. Telmisartan exposure in the first six weeks resulted in intrauterine death in the 18th gestational week.Conclusion: Drugs acting on renin-angiotensin system should be discontinued when pregnancy is detected. Warfarin is contraindicated for use in pregnancy except mechanical heart valve pregnancies with high risk of thromboembolism, as it leads to coumarin embryopathy and nervous system anomalies in the first trimester exposures. Pregnant women should be directed to the teratogenic drug analysis and evaluated for possible increase in drug-related congenital malformation risks at early gestational period. Teratogenic risk counselling and follow-up ensures reliable data on drug safety during pregnancy.
Knowledge, attitude, and practice of contraception among women attending a tertiary care hospital
Authors: Agrawal Alpana , Saxena Rashmi , Gupta Manisha , Agarwal Neelima , Shubham Divya , Tyagi Anuradha
Published: May 2019

Background: This study was carried out to assess the knowledge, attitude and practice of contraceptive methods among women attending a tertiary care hospital, to know the influence of various factors on use of contraceptives and to identify the reasons for not using contraception.Methods: A cross sectional, observational study was conducted in Obstetrics OPD, Santosh Medical College, Ghaziabad. 408 married women of reproductive age group (15-45 years), randomly selected, were interviewed with the help of a predesigned questionnaire to elicit information regarding their demographic profile, knowledge, attitude and practice of contraception.Results: In our study 73.3% women interviewed were aware about family planning methods.  Awareness was lowest among adolescents less than 20 years of age (28%) and highest among 31-35 yr age group (84.1%). The main source of knowledge was “friends/relatives” (37.8%) and mass media (26.8%). Awareness was high in Para-1 (96.5%), higher SES (97.4%), with higher education (90.7%), in working women (80.4%), women living in nuclear families (80.2%) and Hindu females (73.7%).  But in spite of high level of awareness, contraception usage was less (54.4%), the main reason being fear and misconceptions regarding contraceptives.Conclusions: It can be concluded that high level of knowledge and awareness does not match with contraceptive usage rate. Converting family planning knowledge into practice is the real challenge for India. Hence, we recommend sustained efforts to increase awareness and motivation for contraceptive use through more information, education and communication with the reproductive age couples, and improved social and welfare services.
Impact of different grades of anaemia severity during pregnancy on maternal and neonatal outcomes: a prospective study
Authors: Dahiya Sonia , Malik Nisha , Pandey Kiran , Gupta Renu , Perumal Vanamail , Singh Vikram
Published: May 2019

Background: Anaemia in pregnancy is a universal health problem that may cause a number of obstetrical and neonatal complications. This prospective observational study aims to evaluate and compare maternal and neonatal outcomes in different grades of anaemia severity.Methods: A total of 400 pregnant women with anaemia in third trimester were classified into three groups according to haemoglobin (Hb) levels-group I with Hb:10-10.9 g/dl, group II with Hb:7-9.9g/dl and group III with Hb<7 g/dl. Maternal and neonatal outcomes of women with different severity of anaemia were analyzed and compared. Two groups means were compared by Student’s t-independent test and more than two groups means by one way analysis of variance test followed by post-hoc pairwise comparison using Bonferroni test.Results: The prevalence of anaemia in the study population was 35.2%. Mild, moderate and severe anaemia were found in 58% (n=232), 29.0% (n=116) and 13% (n=52) women respectively. A statistically significant difference in maternal outcomes such as Preterm labor (p=0.001), Prelabor premature rupture of membranes (p=0.044), Intrauterine growth restriction (p=0.002) and postpartum hemorrhage (p=0.001) was observed amongst the three groups. Cardiac failure occurred in 26.9% (n=14) and mortality in 13.4% (n=7) women with severe anaemia. Amongst the neonatal morbidities, the rate of low birth weight, preterm birth, respiratory distress syndrome, septicaemia, pneumonitis and jaundice revealed an increasing trend with rising severity of anaemia which was statistically significant.Conclusions: Targeted interventions addressing early detection and appropriate treatment in early pregnancy can prevent and avoid dismal maternal and neonatal consequences.
Identification of factors determining the initiation of breastfeeding in postnatal women in a tertiary care centre: an observational study
Authors: Gupta Manisha , Agarwal Neelima , Agrawal Alpana
Published: May 2019

Background: The WHO recommends that mothers worldwide to initiate breastfeeding within an hour of delivery to achieve optimal growth, development and health but the breastfeeding rates remain far below the recommended standards. The aim of this study was to find the prevalence of delay in initiation of breast feeding, to identify various factors which determine the initiation of breastfeeding and to correlate their association with delayed onset of breast feeding.Methods: Hundred and thirty six postnatal women, who delivered in Santosh Medical College and Hospital, Ghaziabad, were recruited in the study. They were interviewed after their informed consent using a pretested structured questionnaire. Socio-demographic and obstetric factors were compared between subjects who initiated breast feeding in less than and more than 1 hours. Frequencies were calculated for different variables. Data was statistically analyzed and p value of <0.05 was taken significant.Results: The prevalence of delay in initiation of breast feeding in our study was found to be 74.2% (n=101).The mean time of initiation of breast feeding was 18.43 hours. Significant association (p <0.05) was found in various sociodemographic, obstetrical and social factors.Conclusions: Identifying mothers at risk of delayed breastfeeding initiation should be the target for breastfeeding promotion during prenatal, antenatal as well as postnatal period. Public health officials and health care providers should consider interventions to promote and support early initiation of breast feeding.
Manual vacuum aspiration: a safe and effective surgical management of early pregnancy loss
Authors: Azman Aishah , Sakri Noor Asikin Mohd , Mohd Kusni Nor Adibah , Mansor Nurul Hidayah , Zakaria Zahar Azuar
Published: May 2019

Background: Manual vacuum aspiration (MVA) is an alternative to the standard sharp uterine curettage, performed under local anaesthetic or sedation in the daycare setting. The objectives of this study were to assess the efficacy and safety of MVA, the pain perception and the factors related to it.Methods: This was a prospective observational study of 58 consecutive patients who had undergone Manual Vacuum Aspiration (MVA) in Early Pregnancy Assessment Clinic, Hospital Kemaman between January and December 2017. Data on the patients’ characteristics and the procedures were analysed.Results: The efficacy of the procedure was 96.5% (56/58) with no major complication recorded. Majority of the patients (91.3%) reported mild to moderate pain with 2/3 of them agreed to undergo MVA in the future and would recommend it to other patients. There was no significant difference in mean pain score between different groups of women (parity, education levels, occupations, previous uterine evacuation) or procedural techniques (analgesia, sedation, cervical block, cervical dilatation, procedure duration, number of aspiration passes).Conclusions: MVA is safe and well accepted procedure for out-patient surgical evacuation of early miscarriages.
Impact of changing life style on age of menarche
Authors: Upadhyay Kritika , Dhok Archana , Jaiswal Arpita
Published: May 2019

Background: Menarche marks the beginning of the reproductive phase in a woman’s life or the onset of puberty Menarche is said to be early when it begins before the age of 8 years in a girl’s life. Early menarche can turn up into many consequences. This can only be controlled by carefully exploring and analyzing the factors causing early menarche. This study aims to assess the impact of changing lifestyle on age of menarche.Methods: It is a prospective cross-sectional study, included 112 subjects in group I (girls had their menarche at the age of <11 years) and 88 subjects in group II (Girls had their menarche at the age between 12-14 years). A self-made questionnaire was used for collecting the data.Results: It is found that  80.32% girls from group I and 47.73% girls from group II consume junk food daily or 2-3 times per week. 66.07% girls from group I and 51.14% girls from group II play indoor games daily or 2-3 times per week. 52.86% girls from group I and 26.14% girls from group II go to hotel once a week and 57.14% girls from group I and 73.86% girls from group II go to hotel occasionally.Conclusions: Girls who are not much interested in playing outdoor games, more frequently go to hotel, eat more junk food and consume more amount of fats in the daily home-made food have a significant lowering in the age of menarche.
Prevalence of vitamin D deficiency in antenatal women
Authors: Chandel Anu Bala , Mittal Rita , Sharma Anoop , Mittal Shivika , Samyal Poonam
Published: May 2019

Background: Vitamin D has an increasingly recognised repertoire of non-classical actions, such as promoting insulin action and secretion, immune modulation and lung development. It therefore has the potential to influence many factors in the developing fetus. Several studies reported the relationship between maternal vitamin D deficiency and adverse maternal and fetal outcomes including gestational diabetes, preeclampsia, preterm labour, low birth weight and increased rate of caesarean section. The present study was undertaken to study the prevalence of vitamin D deficiency in antenatal women of Shimla, India.Methods: The study was conducted in the department of Obstetrics and Gynaecology, Kamla Nehru Hospital, Shimla, India over a period of 12 months. Six hundred women were included in the study.Results: Out of 600 subjects, 568 (94.67%) subjects had vitamin D deficiency and only 32 (5.33%) subjects had sufficient vitamin D levels. Vitamin D deficiency was more common in the vegetarians, dark skinned subjects and in those who were taking vitamin D supplements.Conclusions: It is concluded from this study that there is high prevalence of vitamin D deficiency in antenatal women of Shimla, India.
Comparative study of efficiency of vaginal versus oral misoprostol along with mifepristone for first trimester medical termination of pregnancy
Authors: Mehta Latika R. , Agrawal Grishma P.
Published: May 2019

Background: Authors estimate that 15.6 million abortions (14.1 million-17.3 million) occurred in India in 2015. Incomplete abortion is a known disadvantage of medical method of abortion reported in 0.2-3% of cases. Though Misoprostol can be used with different routes including oral, sublingual and vaginal, few evidences are available in drug effectiveness as well as its related side effects when used through different routes and more so in India. The present study is aimed to compare the efficacy of misoprostal in first trimester abortion when taken vaginally as compared to orally. Thus, whichever route results in lower rates of incomplete abortions, can be employed in our health set up, minimizing the complications of failed first trimester MTP.Methods: An experimental study was conducted on 74 women seeking termination of pregnancy within 9 weeks of amenorrhea during the period of 9 months in a tertiary care institute. Tablet mifepristone 200 mg was given to all participants. After 48 hours, 37 women were given 800 mcg tablet of Misoprostol for oral consumption while other 37 women were given 800 mcg Misoprostol for self-administering vaginally. Abortion status and complications were checked.Results: The complete abortion rates in vaginal group and oral group were 97.3% and 86.49 % respectively. Satisfaction was more in case of vaginal misoprostol, while side effects were similar in both groups.Conclusions: Mifepristone with vaginal misoprostol was more effective as compared to oral misoprostol for first trimester abortion.
Place of the misoprostol in 600 µg in intrarectale in case of hemorrhage of the post partum by uterine atony at the Befelatanana University Hospital Centre of Obstetric Gynecology in Antananarivo, Madagascar
Authors: Aimé Rainibarijaona Lanto Nirina , Martial Rakotonirina Andriamaro , Tanjona Ratsiatosika Andriamanetsiarivo , Romuald Randriamahavonjy , Lovamampionona Andriamihajason , Andrianampanalinarivo Hery Rakotovao
Published: May 2019

Background: The hemorrhage of the post-partum (HPP) represents a major problem of public health because it hires the vital and obstetrical forecast of the mother in case of delay of taking care. Present study aims at assessing the effectiveness of the administration of 03 tablets of misoprostol in intra-rectal in the taking care of HPP by uterine atony and to determine the épidémio-clinical profile of HPP by atony.Methods: Authors performed a retrospective and descriptive study concerning the effectiveness of the misoprostol in the taking care of HPP by uterine atony. This study started from December 1st, 2016 till March 31st, 2017. The data processing was performed by Epi info 7 and Excel.Results: The rate of HPP represented 3.8% deliveries which 69.4% was due to uterine atony. HPP by uterine atony represented 2.60% deliveries. It happened at the women from 25 to 34 years old (46.16%), pauciparous (76.93%), with a lower working time at 8 hours (71.15%) and having performed at least 4 CPN (63.47%), giving of urgent babies with a medium weight of 3073.43 g. The administration of the misoprostol was efficient in 90.40% and we noticed no side effect or of serious complications during the taking care of HPP by uterine atony.Conclusions: HPP remains another major preoccupation of the obstetricians in our country because it is an emergency that can put into play the vital forecast and which requires a catch in quick load. The administration of 03 tablets (600 µg) of misoprostol in intra-rectal during HPP by uterine atony deserves its place in the armory of taking care because it is a sure method, efficient and easy to manipulate.
Causes and management of post-partum hemorrhage at tertiary care center, Rajasthan, India
Authors: Gora Kamlesh , Depan Anju , Yadav Kanti , Benwal Devendra
Published: May 2019

Background: PPH is responsible for 25% of all maternal deaths. In India, PPH incidence in India is 2%-4% following vaginal delivery and 6% following cesarean section. PPH as the important cause of 19.9% of maternal mortality in India. The objectives of the study were to study the incidence, risk factors, cause, morbidity and mortality pattern and management of PPH.Methods: This is a cross-sectional study conducted among 102 pregnant women selected by convenient sampling and admitted in labour room during the study period who will be deliver by vaginally or by caesarean section. The patient having PPH were divided into two groups: Group I: Patients having primary atonic PPH, Group II: Patients having traumatic PPH.Results: Mean age of participants was 33.6 and 32.9 years, 59.3 and 51.2 have ‘0’ parity, mean BMI 22.8 and 23.9 kg/m2, 34.6% and 17.1 babies were delivered by LSCS, 11.7% and 12.2% have history of PPH in the group of atonic and traumatic respectively. In the group of atonic PPH cases, 77.2%, 15.4%, 4.3% and 3.1% cases managed by the method of ‘Uterotonics +<2 blood transfusions’, ‘Uterotonics + >2blood transfusions’, ‘Perineal Tear Repair’ and ‘Surgical Intervention’ respectively. All the traumatic PPH cases (100.0%) were managed by ‘surgical intervention’.Conclusions: A multi-disciplinary approach include medical, mechanical, surgical and radiological is required in severe haemorrhage. Availability of blood and blood products is very crucial. Prediction and assessment of blood loss and timely identification of uterine atony are remaining the cornerstone for prompt and effective management of PPH.
The prospective study of laparoscopic finding in infertility cases
Authors: . Shruti , Sen Sangeeta
Published: May 2019

Background: Infertility is a global reproductive health issue that affects many individuals and family. The aim of the present study was to evaluate the laparoscopic finding in infertility cases.Methods: Present study is a prospective study on laparoscopic evaluation of female infertility at Panna Dhai Mahila Chikitsalaya, Udaipur, Rajasthan, India. This study was done for the duration of one year from January 2017 to December 2017. Present study included total 100 cases randomly selected attending OBG OPD with both primary and secondary infertility.Results: Out of 100 cases infertile women 62 cases (62%) were of primary infertility and 38 cases (38%) were of secondary infertility. The mean duration of infertility was 3.7 years. Laparoscopic finding were as follow 42% had polycystic ovaries, 33% women had tubal pathology diagnosed on laparoscopy in which 22 women had tubal blocks diagnosed on chromopertubation and among them 19 had cornual block and 3 had ampullary block ,11% uterine finding and 7 women had adhesions in the pouch of douglas and one women had obliterated. About 20 women (20%) conceived during the period of study. Seven women had post laparoscopic complication two women complained of shoulder pain and another four of abdominal pain post operatively.Conclusions: Laparoscopy is the gold standard for diagnosing tubal factors, peritoneal factors, endometriosis and adhesions, because no other imaging technique provides the same degree of sensitivity and specificity and it should be considered in infertility workup for early treatment decision.
Study of diagnosis and management of ectopic pregnancy
Authors: Patel Seema , Desai Ajesh
Published: May 2019

Background: Diagnosis of ectopic pregnancy was frequently missed. Aim of the study was to determine the clinical presentation, and treatment associated with ectopic pregnancy.Methods: This is a prospective study which was carried out at Obstetrics and Gynaecology department, GMERS SOLA civil hospital from August 2017 to October 2018. Total 416 patients were admitted during study period out of them 50 patients diagnosed with ectopic pregnancy were enrolled in the study and information was collected and analysed.Results: 80% patients were between the age group of 21-30 years. 56% patients were nulliparous. Amenorrhea (92%) with lower abdominal pain (94%) is the most common presenting symptom. 26% of patients show typical triad of amenorrhea, abdominal pain and bleeding per vagina. UPT and USG were most commonly performed investigations. 96% cases showed UPT positive. 100% USG showed adnexal pathology. Serum beta-hCG was done in 37 patients as an aid for diagnosis and to decide the line of management. Conservative medical management with Injection MTX was done in 4 patients of which 1 patients required laparotomy later on. Surgical management was done in 90% of patients. Laparoscopic management was done in 54% of cases.Conclusions: Early diagnosis and timely intervention in the form of conservative or surgical treatment will help in reducing the morbidity and mortality associated with ectopic pregnancy.
Level of serum uric acid in patients with preeclampsia compared to controls and its relation to feto-maternal outcome
Authors: Meena Ramraj , Pachori Purnima , Chaudhary Sandhya , . Chandrakanta
Published: May 2019

Background: Uric acid is the final product of the purine metabolism in humans. The two final reactions in its production which catalyze the conversion of hypoxanthine to xanthine and the latter to uric acid are catalyzed by the enzyme xanthine oxidoreductase. The role of uric acid in the progression of prediabetes to diabetes has been known. Serum uric acid has been shown to be associated with cardiovascular disease, hypertension, and chronic kidney disease. The present study was done to see the level of uric acid in preeclampsia and  healthy pregnant controls, to relate serum uric acid results to the severity of hypertension and its relation to fetomaternal outcome in patients attending OPD at RMC Ajmer.Methods: 100 cases of preeclampsia of age group between 20-40 year and gestational age ≥28 weeks and 100 normal healthy women with similar gestational age and age group were included in the study and maternal serum uric acid was estimated in both groups.Results: Mean serum uric acid levels in preeclampsia was 7.65±081 mg/dl and 3.21±072 mg/dl in control group. Perinatal complication was more in case group, 74 % were preterm compared to 11% in control group. Mean birth weight in study group was 2.07 kg, of which 24% babies were VLBW 52% were LBW, and 24% babies had normal birth weight, in control group mean birth weight was 2.82 kg. The difference was found to be statistically signiﬁcant (p value 0.001). In the study group, the MSUA concentration is found higher in LBW and VLBW babies compared to normal birth weight babies.Conclusions: There is a positive correlation between SUA & severity of preeclampsia, and a signiﬁcant adverse fetal outcome is observed with raised MSUA in preeclamptic patients.
Comparative study on usefulness of modified WHO Partograph in management of labour at one of the rural teaching institutes of Gujarat, India
Authors: Ninama Shilpa N. , Gandhi Mayur R.
Published: May 2019

Background: Modified WHO Partograph is a simple, inexpensive pre-printed form on which labour observation are recorded. It generally comprises three sections of information: maternal condition, fetal condition and labor progress. To study on usefulness of Modified WHO Partograph in management of labour of low risk women, this indirectly improved maternal and perinatal outcome.Methods: In this study the progress of labour of 150 women with uncomplicated full term pregnancies with cephalic presentation in active labour was studied using modified WHO partograph. 150 historical matched controls comprising of low risk women who delivered without the use of partograph were identified from the labour register and their course of labour studied. The hospital records were studied to obtain the demographic variables. Maternal and perinatal outcome was analyzed for both cases and controls.Results: The emergency cesarean section rate was reduced from 38.7% in controls to 24.7% in cases and both are significant statistically. None of the cases had labour beyond 16 hours, thus indicating significant reduction in prolonged labour. Neonatal intensive care admissions decreased from 18.6% in controls to 6% in cases indicating an improved maternal and neonatal outcome.Conclusions: Modified WHO Partograph work as “early alarming warning system” which help in detecting delayed progress of labour which improves maternal as well as perinatal outcome.
Serum urocortin in preterm labor is it an effective biomarker?
Authors: Rund Nancy Mohamed Ali
Published: May 2019

Background: Preterm labor classically defined as delivery before completed 37 gestational weeks. Urocortin a biomarker that have raised recent research interest is a 40-amino acid neuropeptide related to the corticotrophin-releasing factor molecular family. Interestingly urocortin is produced by gestational tissue such as amnion and chorion predictability of preterm labor by biomarker assay could enhance management levels particularly in cases of preterm labor that are considered a frequent clinical scenario in obstetric practice. Aim of the study was to assess and evaluate the serum levels of urocortin predictability capacity in cases that develop preterm labor.Methods: The current research clinical trial was conducted in a prospective way there was two research groups 60 study subjects had threatened preterm labor and 60 normal research study subjects that delivered at term. Comparative analysis was performed for urocortin assay conducted in both research groups in correlation to gathered clinical data obtained from both research groups.Results: Receiver operating characteristic curve (ROC) between preterm and term delivery research groups as regards plasma urocortin level (pg/ml) as a predictor of pre term delivery showing that a cut-off point level >101.3 pg/ml in which statistical sensitivity=88.33%, statistical specificity=75%, positive predictive value=77.9, negative predictive value=86.5.Conclusions: This research finding reveal that maternal serum urocortin is an effective biomarker in predictability of preterm labor; however future research studies should be multicentric in fashion putting in consideration the racial and ethnic differences besides the impact of BMI on maternal serum urocortin indices.
An unusual case of delivery with central rupture of perineum and intact introitus
Authors: Mathe Priyanka , Meena Manisha , Bharti Rekha
Published: May 2019

Most women experience some degree of tear during childbirth and in some these can be extensive. Obstetrics injuries contribute 0.5-15% of vaginal deliveries. Here authors present a case of 23-year-old primigravida who presented at Safdarjung hospital New Delhi, Delhi, India with complaint of pain in perineum and excessive bleeding per vaginum. On examination, introitus was intact and there was central rupture of perineum which involved anal sphincter proximally and rectal mucosa distally. Patient was shifted to operation theatre for exploration and repair. She received 2 units of blood transfusion, antibiotics and laxatives. Patient was discharged on post-operative day 5 in satisfactory condition. Thus, authors emphasise the need of institutional delivery and prevention of perineal injuries which would further obviate the need for surgical repair and associated morbidity. In present era of easy communication and transport we still receive cases of unsupervised deliveries which gives us a strong motive to spread awareness for antenatal visits and care among this population.
Idiopathic aplastic anemia: a rare case report in Jammu and Kashmir region, India
Authors: Sharma Smriti , . Upma , Mani Deep
Published: May 2019

Idiopathic aplastic anemia is a pancytopenia disorder that is a rare but life threatening for both mother and fetus during pregnancy. Association of aplastic anemia with pregnancy is unclear but considered to be interrelated. Bone marrow transplantation is the most effective treatment for adult aplastic anemia but is inadvisable to perform during pregnancy because of the teratogenic effect of immunosuppressive agents or radiation therapy to the growing fetus. Supportive care, withdrawal from offending drugs and involving erythrocytes and platelets transfusion is a promising way to save the life. Here author present a case report of 36-year-old lady with idiopathy aplastic anemia. In this case medical investigation revealed severe anemia of unknown origin. The patient was treated with hematinics, blood transfusion and glucocorticoids. A healthy baby was delivered without evidence of hemolysis at her eight month and one week of pregnancy, the patient recovered and discharged with normal incidence. Being a rare case, it becomes a necessity to report such life-threatening disorder and management. Moreover, to our knowledge this is the first case reported of its kind from Jammu and Kashmir Division of India.
Elevated serum CA 19-9 levels in dermoid cyst: a predictor of ovarian torsion and tissue necrosis?
Authors: Bhatia Ruby , Kaur Simmanjit , Mor Sunita , Kaur Naazbir , Gupta Ritika
Published: May 2019

Dermoid cyst (mature cystic teratoma) with well differentiated derivatives of all the three-germ cell layer is a benign tumour with ovaries being the commonest site. Dermoid cyst accounts for more than half of ovarian tumours in girls below 20 years of age. 80% of dermoid cyst are seen in reproductive age group between 20-40 years. Size of dermoid cyst usually varies between 5-10 cm and it may be bilateral in 10% of cases. Malignant transformation is very rare occurrence only in 1-3% cases, however torsion may occur in 15% of dermoid cyst. Carbohydrate antigen or cancer antigen 19-9 is usually raised in gastrointestinal tumours, pancreatic malignancy, pseudocyst of pancreas. However, it may be raised in some other malignancies and benign condition like torsion of dermoid cyst. Authors report an unusual case of torsion large dermoid cyst with tissue necrosis along with significantly elevates levels of serum CA 19-9. A 30-year-old P1L1 female presented with chief complaint of heaviness and pain lower abdomen and loss of five kilogram weight for last three months. A provisional diagnosis of dermoid was made. Serum CA 19-9 level were 1126 IU significantly raised. An exploratory laparotomy done under regional anaesthesia. A large demoid cyst 12*10 cm with torsion and areas of gangrene in ovarian tissue was seen replacing left ovary. Large and small intestine, stomach, pancreas were explored to rule out any pathology. Histopathology confirmed diagnosis of mature cystic teratoma. There was significant fall in serum Ca 19-9 levels to 247 U/ml two weeks after surgery and levels returned to normal limit six weeks after surgery.
Mifepristone as pre-induction cervical ripening agent in term pregnancy
Authors: Sharma Nikita , Ghose Seetesh , Rathod Setu
Published: May 2019

We hereby report the results of a prospective randomized study where we compared efficacy of mifepristone and prostaglandin (PGE2) gel for pre-induction cervical ripening.
Assessment of management of polytrauma patients in the emergency department in Suez Canal University hospital
Authors: Abdelgeleel Nashwa M. , Salama Khaled Morsy , Ali Mohamed A. , Elsagher Aasha N.
Published: May 2019

Background: Trauma is a serious global health problem, it is the fifth leading cause of significant disability and is still the most frequent cause of death in the first four decades of life, accounting for approximately one in 10 deaths worldwide.Methods: This study is cross sectional prospective study was conducted to evaluate assessment of management of patients according to the advanced trauma life support guideline in Emergency Department at Suez Canal University Hospital. All patients (n=103) were subjected to baseline assessment by history, clinical examination and investigations. The patients were followed up and recorded till the full assessment was done and the decision was made and the fate of the patient was recorded.Results: The majority of the studied patient had motor car crash (55.30%), while motor cycle crash was the second mechanism of trauma (21.40%), run over was the third mechanism (14.60%). Airway management was done (95.1%), cervical spine kept immobilized only in (71.8%). Blood pressure was measured in (97.1%) and 2ry survey assessment, head to toe examination (78.6%), while AMPLE history was taken in minority of cases percentage (33%). Finally majority of patients was admitted in ICU (44.70%), followed by 18.40% of the studied patient died and less than (2%) discharged from the ER.Conclusions: ATLS protocols provide a common framework and organized approach during polytrauma patient’s management. Also, it has been shown to improve outcomes so we should enhance its application in our hospital.
Stapling technology with triple-row and enhanced staple configurations evaluated in a series of 124 consecutive laparoscopic vertical gastrectomies
Authors: Bianchi Alessandro , Pagan-Pomar Alberto , Jimenez-Segovia Marina , Soldevila-Verdeguer Carla , Bonnin-Pascual Jaume , Martinez-Corcoles José Antonio , González-Argenté Xavier Francesc
Published: May 2019

Background: Laparoscopic sleeve gastrectomy (LSG) is a procedure frequently used to treat morbid obesity, due to its simplicity compared to other bariatric techniques. However, LSG can lead to serious complications, such as gastric leakage and bleeding from the staple line. To reduce these complications, seroserosal reinforcement of the mechanical suture line after gastrectomy is generally recommended. In recent decades, studies have focused on the safety of anastomosis with staples, especially compared to manual sewing techniques. Since studies on the improvement of stapling technology are limited, this study arises to compare the clinical results of staple line oversewing versus stapling technology with triple-row and enhanced staple configurations in laparoscopic sleeve gastrectomy.Methods: A retrospective review from a prospectively maintained database of 124 laparoscopic vertical gastrectomies performed at single centre between March 2010 and December 2016. Patients were divided into two groups, with comparable anthropometric parameters and inclusion criteria. Seroserosal reinforcement was used in the first group, and stapling technology with triple-row and enhanced staple configurations in the second. Rates of anastomotic leakage, bleeding, reoperation, and 30-day mortality were compared.Results: In Group 1 the average surgical time was 125 min, whereas in Group 2 it was 87 min. No differences were found between the two groups regarding leakage or bleeding of the staple line.Conclusions: The use of triple-row stapling devices during laparoscopic vertical gastrectomy enables surgical time to be reduced. Further high-quality studies to evaluate the efficacy and effectiveness of stapling technology with triple-row and enhanced staple configurations are needed.
Total thyroidectomy: conventional suture ligation technique versus sutureless techniques
Authors: Ali Mahmoud N. M. , Aldardeer Ahmed Abdelkahaar , Ali Ayman M. A. , Radwan Alaa A.
Published: May 2019

Background: Since the introduction of successful thyroidectomy no change occurred in the technique but with the innovation of sutureless surgery, sutureless thyroidectomy becomes a competitor for the conventional technique. In this study we tried to analyze the outcomes of each.Methods: This was a prospective cross armed uncontrolled randomized study included 65 patients suffering from non-malignant goiter who underwent total thyroidectomy, admitted to Sohag University Hospital from September 2017 to October 2018. Patients were randomly allocated into two groups; Group (S) managed with sutureless thyroidectomy, and Group (C) managed with conventional knot tying technique. The data of the patients were gathered and analyzed considering the operative and post-operative outcomes. All patients were followed-up for 6 -12 months.Results: We found a significantly shorter operative time (p=0.001), also the amount of intra-operative blood loss was highly significant less in Group S (p=0.001). There was higher incidence of post-operative pain in Group C (p<0.001), post-operative drainage volume was highly significantly less in Group S (p=0.001). Regarding post-operative complications; the incidence of recurrent laryngeal nerve paralysis (RLNP) was insignificant between both groups (p=0.38), in the same time the incidence post-operative transient hypocalcaemia was significantly more in Group C (P=0.025). The overall post-operative complication rate was significantly more in Group C (p=0.002). The duration of hospital stay was highly significant shorter in Group S (p=0.0001).Conclusions: The use of Harmonic FOCUS® is beneficial for both patient and surgeon; it is efficient and a trustable safe substitute to the conventional knot tying technique.
Liver abscess: study of etiological factors and different treatment modalities and their clinical implications
Authors: Khosla Abhishek , Ali Iqbal , Shetty Varun
Published: May 2019

Background: Hepatic abscess (HA) can be defined as an encapsulated collection of suppurative material within the liver parenchyma, which may be infected by bacterial, fungal, and/or parasitic micro-organisms. The development of new radiologic techniques, the improvement in microbiologic identification, and the advancement of drainage techniques, as well as improved supportive care, have reduced mortality to 5-30%. The study is undertaken to study the etiology and the impact of the modern methods of treatment on the morbidity and mortality on the different types of liver abscess..Methods: This study was a Prospective Study conducted from July 2016 to September 2018. Participation in the study was purely voluntary.Results: Majority of the patients (29%) were in the age group of 31-40 years with a male preponderance (91%). Diabetes mellitus was a common comorbidity in study subjects. Alcohol consumption was found as a significant risk factor in the development of liver abscess. Sixty eight (68%) patients underwent percutaneous needle aspiration and 27 (27%) patients were managed conservatively. Five (5%) patients required surgical intervention. Four (4%) patients died while 97 (97%) patients survived; 3 (3%) patients had undergone surgery while 1 (1%) patient was percutaneously drained.Conclusions: The most common age group affected by liver abscess was third and fifth decade of life . Males are more commonly affected than females. In case of larger (>5 cm) or 150 ml, Ultrasound guided percutaneous pigtail catheter drainage is a superior therapeutic approach than percutaneous needle aspiration. Surgical intervention is reserved for unresponsive cases.
Is there a role of frozen section of sentinel lymph node in patients with early breast cancer for the management of axilla in India: a prospective study
Authors: Arora Anshika , Chauhan Neena , Saini Sunil , Vishwakarma Nishish , Luthra Tanvi
Published: May 2019

Background: Evaluation of axilla using sentinel lymph node biopsy (SLNB) is the standard of care in node negative early breast cancer. Intra operative assessment of SLNB with frozen section (FS) often guides the surgeon regarding decision for level of axillary dissection. The aim of this study was to evaluate accuracy of FS of SLNB in these patients with histopathology examination (HPE) as the gold standard.Methods: This study was performed between July 2017 and November 2018. After gross evaluation of SLNB, nodes were cut in half and frozen; the other half was preserved for HPE. For FS, nodes were sectioned to 4 mm width and examined.Results: A total of 61 patients underwent SLNB, 55 patients undergoing intra-operative FS. The mean age was 53 years (range 30-84, ± 15.09 SD), primary tumor was clinically T1 in 23.6%, T2 in 76.4% patients. A median of four sentinel nodes were identified, mean size 13.84 mm. On FS SLNB was positive for metastasis in 14 (25.5%), on HPE in 16 (29.1%) patients. There were 13 true positive, 38 true negative, 3 false negative and 1 false positive result for FS. The sensitivity, specificity, positive and negative predictive value, false negative and false positive rates were 81.25%, 97.44%, 92.86%, 92.73%, 18.75% and 2.56% respectively in this study. The overall accuracy of FS of SLNB in early carcinoma breast was found to be 92.73%.Conclusions: An intra-operative FS of the SLN in node negative early breast cancer is a highly sensitive tool in axilla management.