bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of Retrograde Intrarenal Surgery and Micro-Percutaneous Nephrolithotomy for Kidney Stones: A Meta-Analysis
Authors: Gu Zhenhua , Yang Yucheng , Ding Rui , Wang Meili , Pu Jianming , Chen Jian
Published: November 2020

Background: Advances in micro-percutaneous nephrolithotomy (PCNL) for kidney stones have made it an alternative approach to the retrograde intrarenal surgery (RIRS) approach. Nevertheless, the superiority of micro-PCNL over RIRS is still under debate. The results are controversial. Objectives: The purpose of this study was to systematically evaluate the clinical results in patients presenting with kidney stones treated with micro-PCNL or RIRS. Methods: A literature search was done for electronic databases to identify researches that compared micro-PCNL and RIRS till December 2019. The clinical outcome included complications, stone-free rates (SFRs), hemoglobin reduction, length of hospital stay, and operative time. Results: Five articles were included in our study. The pooled results revealed no statistical difference in the rate of complications (OR = 0.99, 95% CI = 0.57–1.74, p = 0.99), length of hospital stay (MD = −0.29, 95% CI = −0.82 to 0.24, p = 0.28), and operative time (MD = −6.63, 95% CI = −27.34 to 14.08, p = 0.53) between the 2 groups. However, significant difference was present in hemoglobin reduction (MD = −0.43, 95% CI = −0.55 to 0.30, p < 0.001) and the SFRs (OR = 0.59, 95% CI = 0.36–0.98, p = 0.04) when comparing RIRS with micro-PCNL. Conclusions: Compared with micro-PCNL to treat kidney stones, RIRS is associated with better stone clearance and bearing higher hemoglobin loss. As the advantages of both technologies have been shown in some fields, the continuation of well-designed clinical trials may be necessary.
Regulatory Single Nucleotide Polymorphism Increases TERT Promoter Activity in Thyroid Carcinoma Cells
Authors: Hirokawa Tatsuya , Arimasu Yuu , Chiba Tomohiro , Nakazato Yoko , Fujiwara Masachika , Kamma Hiroshi
Published: November 2020

Background/Aim: The telomerase reverse transcriptase (TERT) promoter has a regulatory single nucleotide polymorphism (rSNP), rs2853669, and occasionally shows point mutations C228T and C250T. Although C228T and C250T have been well examined to increase TERT promoter activity and are known as risk factors for thyroid carcinoma, the significance of rs2853669 has not been well investigated. This study aimed to clarify the influence of rs2853669 on TERT promoter activity in thyroid carcinoma cells. Materials: Seven of 8 examined thyroid cell lines had rs2853669, 5 had C228T, and 1 had C250T. Results: Three papillary thyroid carcinoma cell lines, harboring both rs2853669 and C228T, showed higher TERT mRNA expression on real-time PCR than the other cell lines. Anaplastic thyroid carcinoma cell lines, in contrast, showed variable TERT mRNA expression depending on the combination of rs2853669, C228T, and C250T. Luciferase assays, performed to compare the influences of rs2853669, C228T, and C250T on TERT promoter activity in thyroid carcinoma, showed that rs2853669, as well as C228T, increased the promoter activity, and the combination of rs2853669 and C228T increased the promoter activity even more strongly than C228T alone. Conclusion: We conclude that the presence of rs2853669 within the TERT promoter could be as significant as the C228T mutation in thyroid carcinoma.
Holmium Laser Enucleation, Laparoscopic Simple Prostatectomy, or Open Prostatectomy: The Role of the Prostate Volume in terms of Operation Time
Authors: Gunseren Kadir Omur , Akdemir Serkan , Çiçek Mehmet Cagatay , Yıldız Ali , Arslan Murat , Yavaşcaoğlu İsmet , Vuruskan Hakan
Published: November 2020

Introduction: To compare the prostate removal speeds of 3 enucleation techniques and to evaluate how the operating times change depending on the prostate volume. Methods: Medical records of patients with 80-g or larger prostates who underwent holmium laser enucleation of the prostate (HoLEP), laparoscopic simple prostatectomy (LSP), or open prostatectomy (OP) due to medical treatment-resistant benign prostatic hyperplasia (BPH) were reviewed retrospectively. Patients were classified into 3 groups according to the surgical procedure. Age, BMI, prostate weights, total operation times, prostate removal speeds, hospitalization and catheterization days, complications, and improvements on functional outcomes in the 3rd month of follow-up were compared between groups. In addition, the association between prostate weight and total operation time was analyzed for each group. Results: HoLEP, LSP, and OP groups consisted of 60, 61, and 37 patients, respectively. While HoLEP was similar to OP in terms of prostate removal speed and total operation time, LSP was statistically slower and required more operation time than HoLEP and OP. There was a relationship between prostate weight and total operation time only in HoLEP. Conclusion: LSP, one of the enucleation techniques in the treatment of large prostates, was slower and required more operation time than HoLEP and OP in terms of total operation time and prostate removal speed. HoLEP seems going to be the fastest candidate for the rapid removal of large prostates in the future.
Preceding T-Cell-Mediated Rejection Is Associated with the Development of Chronic Active Antibody-Mediated Rejection by de Novo Donor-Specific Antibody
Authors: Tsuji Takahiro , Iwasaki Sari , Makita Keishi , Imamoto Teppei , Ishidate Naomichi , Mitsuke Akihiko , Fukuzawa Nobuyuki , Harada Hiroshi , Fukazawa Yuichiro
Published: November 2020

Aim: Chronic active antibody-mediated rejection (CAABMR) is an important cause of late-stage renal allograft loss. Early inflammatory events such as acute rejection and infection after transplantation are considered to be the risk factors of de novo donor-specific antibody (dnDSA) production. In this study, we investigated the relationship between pre­disposing T-cell-mediated rejection and dnDSA-positive CAABMR. Methods: We recruited 365 patients who underwent ABO-compatible renal transplantation at our hospital. Among them, 16 patients diagnosed as having dnDSA-positive CAABMR were designated as a CAABMR group, and 38 randomly selected patients were designated as a control group. All biopsies from 1 month after transplantation were included in the study. The presence or absence of borderline changes (BLCs), acute T-cell-mediated rejection (ATMR), microvascular inflammation (MVI), and C4d positive on peritubular capillaries (C4d-P) was examined. Results: In the CAABMR group, BLC/ATMR was found in 12 cases (75%), and the mean duration until appearance of BLC/ATMR was 282.7 ± 328.7 days. C4d-P was found in 11 cases (68.8%), and the mean duration until its appearance was 1,432 ± 1,307 days. MVI was found in all cases, and the mean duration until its appearance was 1,333 ± 1,126 days. The mean duration until diagnosis of CAABMR was 2,268 ± 1,191 days. In the control group, BLC/ATMR was found in 13 cases (34.2%), and the mean duration until the appearance of BLC/ATMR was 173.1 ± 170.4 days. C4d-P was found in 2 cases (5.3%), and the durations until its appearance were 748 and 1,881 days. No cases of MVI were found in the control group. The frequency of BLC/ATMR was significantly higher in the CAABMR group (p < 0.01). Conclusion: Preceding BLC/ATMR is associated with the development of CAABMR with dnDSA.
Ethnoconstructivism analysis: Study of pedagogic mathematics competence of primary school teachers
Authors: Syahrial Syahrial , Asrial Asrial , Maison Maison , Mukminin Amirul , Kurniawan Dwi Agus
Published: November 2020

The teacher has an important role in realizing quality learning. Qualified teachers are shown with good competence. Teacher competency can be improved through teacher understanding of non-constructivism knowledge in mathematics learning. Teachers can integrate cultural values and local wisdom into mathematical concepts to shape student knowledge. Integrating cultural values and local wisdom into mathematics learning makes students learn through their cultural background experiences. This research wasa descriptive research employed 691 respondents. The instruments in this study were questionnaires, tests and interviews to reinforce quantitative results. The purpose of this study was to determine the level of
 teacher pedagogical knowledge, teacher ethnoconstructivism knowledge, the influence and impact of ethnoconstivism knowledge in mathematics learning. The results of this study indicate the competence of elementary school teachers in Batanghari, Muaro Jambi, and Jambi City tends to be generally not good, and teachers have applied ethno-constructivism in mathematics learning through the use of media, models, and learning strategy. Teachers still encounter many obstacles in the implementation process. And the age range of the teacher has an impact on the level of ethnoconstructivism knowledge in mathematics learning.
The impact of inteprofessional education to health students’ collaborative competencies
Authors: Ernawati Desak Ketut , Utami Desak Ketut Indrasari
Published: November 2020

One of the aims of Interprofessional education (IPE) is to foster collaboration amongst healthcare professionals. IPE has been adopted at Udayana University by involving seven health courses at Udayana University, Bali, Indonesia. These students were assigned to 49 groups which composed the seven health course students. They learned working in collaboration from cases identified in the community. The activities spanned for five semesters. At the beginning of their activities the students received interprofessional collaboration competencies attainment survey (ICCAS). The survey has been validated in the population and has two collaborative competencies, namely communication and collaboration. This was a report of ICCAS employment in Semester III dan IV of the first cohort of IPE Program at Udayana University. 138 students completed the survey in both semesters. A paired-sample t-test was conducted to compare the mean score differences of collaboration and communication in the first and second semesters of attending IPE learning. Whilst, there was no significant differences on the mean score for communication, there was a significant difference in the mean score for pre and post collaboration (94.7±9.7) and (91.0±10.8); t(130)=3.379, p=0.001. These results suggest that the collaboration competencies amongst the seven health courses students reduced after one semester attending IPE activities. These findings indicated that the study design and learning tasks should be amended to ensure students gain the most of their learning in collaboration.
Interaction monitoring model of logo counseling website for college students’ healthy self-esteem
Authors: Engel Jacob Daan , Engel Ventje Jeremias Lewi , Mailoa Evangs
Published: November 2020

The purpose of this research is to develop the client-counselor interaction monitoring model of the logo counseling website. The model attempts to help counselors in guiding and helping the students (clients) to achieve healthy self-esteem. Machine learning techniques integrated into the model will ensure that the recommendations can be available for counselors and supervisors in the near real-time environment. For the first implementation, a chatbot application is developed and tested with excellent responses from the students. Further research is needed to implement the complete specifications of the interaction monitoring model on the logo counseling website.
Comparison of burnout, vigor and education satisfaction of music and art majors in department of fine arts education
Authors: Demirbatır Rasim Erol
Published: November 2020

The success of an educational institution is largely based on student motivation and educational satisfaction and their happiness at their place of education. It is therefore very important to maintain high quality in education to determine the case of students' well-being in order to improve the standards of study. In this regard, the aim of this study was to identify the status of students in terms of their level of burnout, vigor and educational satisfaction at the Department of Fine Arts Education. There were 250 students participated in the study. To determine the level of burnout and vigor, Shirom Melamed Burnout and Vigor Measures were employed, and to measure the educational satisfaction levels, educational satisfaction questionnaire was used. The results show that music majors have lower vigor than art majors. Gender does not have significant effect on any of the scores. Burnout, vigor and educational satisfaction differ according to the year of education for music major, but only vigor differs for art majors. Mother’s education level has significant effect on burnout and vigor for music majors and on education satisfaction for art majors. GPA is not correlated with none of burnout, vigor or educational satisfaction.
Teacher efficacy and attributes on the implementation of tiered instructional frameworks
Authors: Nichols Janet Alys , Nichols William Dee , Rupley William H.
Published: November 2020

United States federal mandates and reforms to address the needs of at-risk students have resulted in many states being required to implement evidence-based practices (EBP) and tiered systems of support (TSS). We examined the relationships between successful implementation of EBP and tiered frameworks, specifically Positive Behavior Interventions and Support (PBIS) and the constructs of teacher self-efficacy, collective efficacy, and teacher attributions. Data were collected using the School-wide Evaluation Tool (SET), Teacher Self-Efficacy Scale (TSES), the Collective Efficacy Scale (CES), and Teachers’ Attributions for Student Behavior Measure (TASBM). Significant correlations were found between PBIS implementation level and 1) Instructional Strategies subscale of the TSES; 2) Collective Efficacy Scale and both of its subscales; and 3) TASBM and its Stable and Blame subscales. Significant differences in mean ratings were found between high implementing schools and low implementing schools on the Instructional Strategies subscale of the TSES, on the CES, and both of its subscale. Results showed a decrease in mean ratings on the Blame subscale of the TASBM in schools that had higher implementation scores on the SET.
The urgency of religious and cultural science in STEM education: A meta data analysis
Authors: Sumarni Woro , Faizah Zulfatul , Subali Bambang , Wiyanto W. , Ellianawati Ellianawati
Published: November 2020

The 21st century education engages students to have higher order thinking and scientific literacy skills. However, these abilities in Indonsia are still relatively low, especially student’s scientific literacy skills. One solution to the problem of low scientific literacy skills in Indonesia is the application of STEM education. However, as technology advances pursued in STEM education, religious and cultural sciences increasingly separate themselves from science. Cultural science is rarely implemented in learning so that many students do not know their own culture. The contra between science and religion also makes students’s perception of religion and science are two independent knowledge and cannot be united. Through literature studies that have been carried out from various journal article search sites, this article discusses how important religious and cultural sciences are to be implemented into STEM education. The relationship between religion and science, culture and science, culture and religion and the urgency of religion and culture in STEM education are also discussed in this article. The results of this study propose solutions so that science education can be implemented with RE-STEM learning to overcome the gap between religion, culture and science. So, that students will have a more balanced knowledge in religion, ethnoscience and science from RE-STEM integration.
Business students’ perspectives: What makes successful group performance?
Authors: Rantung Rinny Cherill , Sarmita Reggy Nelson
Published: November 2020

Purpose of this study was to identify factors contributing to the successful group performance from the perspective of business students. The in-depth interview was done followed by a survey derived forty-five items variables, after some tests 21 items variables removed due to low item remainder coefficient resulted in 24 items questionnaires. A total of 355 respondents participated during the survey. Exploratory factor analysis with principal factor extraction was performed and five contributing factors were extracted. Those factors are cohesiveness, inter-relationship, norms, diversity and appointed of team leader.
Views of primary Thai teachers toward STREAM education
Authors: Nuangchalerm Prasart , Prachagool Veena , Prommaboon Treekom , Juhji Juhji , Imroatun Imroatun , Khaeroni Khaeroni
Published: November 2020

This study employed survey method for exploring views of teachers toward science, technology, reading, engineering, arts and math science, technology, reading, engineering, arts and math (STREAM) education. Primary teachers were asked their views through questionnaires after STREAM education workshop. Results revealed that teachers have holistic view and having positive view towards STREAM education even though all of them are not science or mathematics teachers. Change in belief and way of practices can allow teachers to do STREAM education in every classroom, design-based learning and creative classroom should be promoted as well. However, holistic view will be more effective into classroom, technology and other supporting learning environments should be prepared.
Teachers’ strategies on teaching grammar: Facts and expectations of senior high school teachers at Ambon
Authors: Souisa Threesje Roza , Yanuarius Lelyemin
Published: November 2020

This study is aimed at describing the English as a Foreign Language (EFL) senior high schools’ teachers’ perceptions on grammar teaching; their teaching strategies which are the most and less frequently applied in their classroom practices and the challenges that they have in teaching grammar. Explanatory mixed approaches were conducted involving 63 teachers as the sample population in collecting quantitative data, and five selected teachers as participants for collecting the qualitative data. The findings showed that teachers' perceptions of grammar teaching are based on their conceptual knowledge as they have experienced it and it is based on grammar theories. The teachers applied vary grammar approaches and strategies but they still face with the challenges in teaching grammar such as students' learning styles and less of teaching references.
Reframing the effectiveness of feedback in improving teaching and learning achievement
Authors: Selvaraj Anne Malar , Azman Hazita
Published: November 2020

Student feedback is established as an imperative learning and teaching technique, but feedback from students is less likely. The potential of feedback to boost learning outcomes refers to scholarly writing and is considered together as one of the most impressive methods for enhancing the success of students. In education, there is, nevertheless a lack of clarification about what feedback means and far less clarification on how one should interpret it. Feedback guides students to learn and supports them in order to achieve the aim of the lesson. The goal of this paper is to discuss teacherwritten reviews and obstacles to student feedback in order to recognise the usefulness of feedback in the education domain. Feedback from students illustrates the comprehensions, boundaries and features that knowledge should be compiled and employed to establish work or learning approach. The assessment study renders the appropriate feedback, and, in this manner, the students learn how to accomplish their learning goals. While feedback is not exclusively evaluated, these are the essential ingredients of making evaluation a mechanism for teachers’ and students’ future learning.
An educational game on the theories of driver education curriculum: An evaluation
Authors: Othman Zainab , Zain Nurul Hidayah Mat , Ismail Ismassabah , Affandi Sharifah , Noh Nor Azida Mohamed , Yasin Anita Mohd
Published: November 2020

The purpose of this study was to evaluate the effectiveness of using an educational game application among driving school students on their understanding of driving rules and regulations. The application was developed and named as An Educational Game on the Theories of Driver Education Curriculum (DEC) to help students improve their visualization, understanding and memorization of the theories of driving rules and regulations as well as to be more prepared before taking the driving theory test. A preliminary study was conducted and it indicated that students had a hard time in visualizing, understanding and memorizing the theories of driving. The Game Development Life Cycle (GDLC) was implemented as a methodology to develop the DEC application which consists of initiation, pre-production, production, testing, beta, and release phases. The effectiveness of the DEC application was measured by Game-Based Learning Evaluation Model (GEM). The findings indicated that educational game helped students to visualize, memorize and understand the theories of driving easily.
The relationship between preschool teachers’ self-efficacy beliefs and their teaching attitudes
Authors: Kırkıç Kamil Arif , Çetinkaya Fatma
Published: November 2020

This study examined the relationship between preschool teachers’ selfefficacy beliefs and their teaching attitudes. In the study, it was considered whether preschool teachers’ self-efficacy beliefs and their teaching attitudes change in terms of certain variables. The research was carried out using a correlational survey model. The target population of the study is the preschool teachers working in Küçükçekmece district, İstanbul Province, in the 2017-2018 academic year. The working group consists of 264 preschool teachers working at the schools in said district. The following assessment instruments were used in the research: “Personal Information Form,” “Preschool Teachers’ Self-efficacy Beliefs Scale,” to identify preschool teachers’ self-efficacy beliefs and ‘Preschool Teachers’ Teaching Attitudes Scale’ to determine the teachers’ attitudes. The obtained data were analyzed using Pearson multiplication moment correlation analysis, and Regression analysis was performed to determine the level of self-efficacy beliefs of preschool teachers affecting teaching attitudes. Preschool teachers were found to have full self-efficacy beliefs in the teaching-learning process, communication skills, planning, and regulation of learning environments and classroom management, and firm self-efficacy beliefs in family participation. Teachers’ attitudes of preschool teachers were found to be democratic at the highest level, followed by autocratic and laissez-faire at the lowest level. As a result of the regression analysis made to determine the level of the effect of self-efficacy beliefs of preschool teachers on their teaching attitudes, the learning and teaching process positively predicts democratic teaching attitudes and negatively predicts laissez-faire attitudes.
Blogging in ESL class- gender-based attitude of the engineering students
Authors: Khatoon Sahib , Abidin Muhammad Jafre Zainol , Mirza Quratulain , Hussain Ashfaq
Published: November 2020

Online learning has given a new context to the teaching and learning environment. This virtual environment changes the attitude of students in language learning. This study aimed to look into the difference among the engineering students' attitudes towards blogging in an ESL class in terms of gender and the effect of multimodal features on their reading attitude. The research method adopted in the present study relied on a qualitative approach. Engineering students from computer science engineering from local public engineering university Mehran University of Engineering and Technology Jamshoro (MUET) were taught English under blogging and were interviewed. Respondents’ attitude is mainly positive towards blogging. There were very few differences pointed out from their attitude towards blogging.
Exploring STEAM teaching in preschool using Fred Rogers approach
Authors: Awang Zahiroh , Yakob Nooraida , Hamzah Aswati , Talling Mohd Mernan
Published: November 2020

The culture of Science, Technology, Engineering, Art and Mathematics (STEAM) teaching is still new among preschool teachers. Nevertheless, STEAM teaching is seen as challenging to be implemented if there is no clear guideline prepared by qualified experts. Therefore, a need analysis on STEAM teaching strategies ought to be conducted to ensure the implementation of STEAM teaching its related problems may be attended. This research aimed to explore experts’ perceptions about Fred Rogers’ STEAM as a STEAM teaching strategy approach as a considered method to be taught in preschools. This need analysis employed semi structured interviews with four experts. The obtained findings were categorized and analysed thematically. Five themes were identified: 1) features and needs of STEAM education, 2) inquiry-based learning 3) learning by doing activities, 4) interesting and systematic teaching strategies and 5) suitability with children’ development and practices. The research findings benefit preschool teachers in selecting and implementing STEAM teaching strategies based on experts’ opinion. Besides, it is anticipated to help teachers to conduct meaningful and effective STEAM teaching with preschool children.
Do a science process skills affect on critical thinking in science? Differences in urban and rural
Authors: Darmaji Darmaji , Kurniawan Dwi Agus , Astalini Astalini , Perdana Rahmat , Kuswanto Kuswanto , Ikhlas Muhammad
Published: November 2020

The study used mixed-method design. Sample size of this study was 689 students employed total sampling technique. This study revealed that science process skill of students in learning science whether urban and rural areas are good. The independent sample t-test showed that there was a significance difference in students' science process skill in urban school (M = 3.175, SD = 0.178) and in rural schools (M = 2.482, SD = 0.182); (t (687) = 18.224, p<0.01. The independent sample t-test showed that there was a significance difference in students' critical thinking in urban school (M = 5.058, SD = 0.163) and in rural schools (M = 3.436, SD = 0.152); t (687) = 17.224, p<0.001. Lastly, the regression shows the level of contribution students’ science process skill influence as much as 51.5% for critical thinking. This study was found that student science process skill affects critical thinking in learning science. Moreover, students' science process skill and critical thinking in urban better than rural.
Perceptions and experiences of students on the use of interactive online learning technologies in Mauritius
Authors: Ramkissoon Parmeswar , Belle Louis Jinot , Bhurosy Trishnee
Published: November 2020

With the advent of e-learning, advocates use the term interactivity instead of interaction among students, and between the teacher and the students. Many universities use Moodle for online teaching and learning. This paper explores the perceptions and experiences of students in three Higher Education Institutions (HEIs) in Mauritius. A mixed-methods approach was used, with an online survey questionnaire administered to 600 students and focus group discussions were conducted with 15 students from these institutions. It was found that 68.4% of respondents used WhatsApp compared to only 23.6% of them who used the e-learning platform, Moodle. There were no associations between the use or frequency of using WhatsApp or Facebook and the types of HEI to which the students belonged. Students preferred WhatsApp due to its facility for knowledge sharing and construction, its interactivity, its usability, respect for privacy and instant communication. From the findings, it is recommended that HEIs bring a shift in their approaches to teaching and learning from cognitivism to socio-constructivism, connectivism and heutagogy.
Guiding principles and practices of peace education followed in secondary schools of Mizoram
Authors: Mishra Lokanath , Gupta Tushar , Shree Abha
Published: November 2020

The significance of peace education is universally recognized for a safe and prospering future for the world at school level as peace education aims at equipping the future citizens with necessary knowledge, attitude and skills so that they would acknowledge and respect all kinds of diversity and understand human dignity. This paper is based on an empirical research aiming how far guiding principles and practices of peace education followed in secondary schools of Mizoram. The concept of peace education, guiding principles of peace education and practices on peace-related activities being followed in the secondary schools of Mizoram were explored. The study revealed that peace education was not being taught as a separate subject. Peace education component was infused in the existing curriculum and also was being taught through co-curricular and extra-curricular activities. Besides, teachers must reflect in their behavior all the guiding principles of peace. They should encourage the students for critical thinking, reasoning, develop awareness on societal problems and issues, broaden their outlook, concentrate on studies, and to be associated with various activities. In Mizoram, students’ unions and church organizations used to play a prominent role in shaping and moulding the character of the people starting from the early stage of life which ultimately benefits the society and the nation. However, in the context of rapid change in social structure and modernization process, there is need for inculcating the values of peace for which schools have to play important role.
A systematic review of parental attitude and preferences towards implementation of sexuality education
Authors: Kee-Jiar Yeo , Shih-Hui Lee
Published: November 2020

Parents play a unique role in providing and facilitating their children in acquirement of sexual and reproductive health knowledge. The purpose of this study is to provide an overview of parents’ attitude, preferences towards sexuality education (SE) and factors that contributed to their attitudes and perceptions based on review of relevant literature. The articles were retrieved via electronic databases, and manually examined to identify the studies that addressed the research questions. There were 29 studies with a total of 22,213 parents involved which published in peer-reviewed journals between the year 2000 and 2018 were selected and reviewed systematically. The findings emerged from the review were categorized into three main themes which included parental attitudes, parental preferences towards the implementation of SE and the factors contributed to their attitudes and perceptions. Most studies revealed that parents showed positive attitudes and support the inclusion of SE in school. They preferred age-appropriated SE to be introduced in elementary schools and secondary schools. Some parents supported SE which is aligned with religious teaching and cultural. Demographic factors, parents’ sexuality knowledge, religious and cultural factors could affect parental attitudes and perceptions towards SE. This understanding could be useful for policymakers and educators to encourage collaboration with parents to strengthen the effectiveness of the program and scale up SE to benefit the young generation.
Efforts to increase nutritional status among Cytomegalovirus (CMV) infected children
Authors: Maulida Iroma , Prastiwi Ratih Sakti , Umriaty Umriaty
Published: November 2020

Malnutrition has an interrelated relationship with infectious diseases, where infection can occur malnutrition and can cause malnutrition in children. Children who infected with CMV need an increase in nutritional status, but with malnutrition, the recovery process and the body's immune enhancement cannot be optimal. This study aimed to identify the efforts to improve the nutritional status of children infected with CMV in Tegal, Central Java, Indonesia. This study was a qualitative study with phenomenological approach. The informants were parents or caregivers of the children infected with CMV. Data obtained through interviews and observations, which then analyzed through the stages of data reduction-presentation-drawing conclusions. Data were analyzed using triangulation methods. The results showed that the nutritional status of children after recovery of CMV infection had increased. That was because the informant always ensures nutrients needed even given using a soft texture and gradually increase to rough. The tendency of informants to provide the same food has the risk of increasing the deficiency of micronutrients in children. Therefore we need an effort to improve the provision of food variations in children.
Mercury and its effect on human health: a review of the literature
Authors: Zulaikhah Siti Thomas , Wahyuwibowo Joko , Pratama Arrizki Azka
Published: November 2020

Mercury in human body is a free radical that can cause depletion of glutathione (GSH) and hoarding of H2O2, leading to shorten the age of erythrocytes and cause haemolysis. Approximately 90% organic form can be absorbed by the intestinal wall, while inorganic forms are only about 10%. The initial form can also penetrate the blood and placental barrier so that it can cause teratogenic effects and nervous disorders. The effects of mercury toxicity on humans depend on the chemical form of mercury, dosage, age of people exposed, length of exposure, entry into the body, fish diet and consumption of seafood. Mercury is able to bind sulfidril proteins in cells resulting in nonspecific cell injury or even cell death, cessation of microtubule formation, enzyme inhibition, oxidative stress, cessation of protein and DNA synthesis, and autoimmune responses. Classified into a very toxic metal, mercury can trigger the formation of ROS, hydrogen peroxide, lipid peroxidation, hydroxyl radicals that can inhibit enzymes, cell damage, DNA damage, protein structure damage, disruption on the body's antioxidant metabolism, especially superoxide dismutase (SOD) and glutathione peroxidase (GPx). Mercury exposure is associated with an increased risk of hypertension, myocardial infarction, coronary dysfunction, and atherosclerosis. This review is clearly in line to investigate the effect of mercury on human health based on previous research, article and other literature sources.
Bibliometric analysis of Asian Pacific Journal of Tropical Medicine from 2008 to 2019
Authors: Musa Taha Hussein , Idriss Arbab Abdelaziz Adam , Musa Hassan Hussein
Published: November 2020

The purpose of the study is to assess the scientific research productions in Asian Pacific Journal of Tropical Medicine (APJTM) from its first issue up to Dec 2019. We used the Web of Science Core Collection (SCI-EXPANDED, SSCI) to extract the relevant documents. Additionally, the data analysis using ORIGIN PRO 2018, HistCite, bibliometrix R-package, and VOSviewer. Var1.6.6. A total of 2,137 publications of APJTM. A total of 2,136 documents were retrieved, with received 13956 citations, with an average mean 6.63 citations per article, an h-index of 38. The most frequently occurring keywords in this analysis were Malaria, dengue, apoptosis, antioxidant, rate, invasion and anopheles stephesi and inflammation. The study provided the comprehensive and general overview for APJTM journal over its history from the first issue up-to-date. Moreover, the findings provide an insight into the frequency of citations for top-cited articles published in APJTM as well as the quality of the works, journals, trends of publications steering in APJTM.
Response time, waiting time and service quality in emergency department
Authors: Hidayat Nur , Ahsan Ahsan , Rahayu Masruroh , Lestari Retno
Published: November 2020

Response time and waiting time were key performance indicators in the emergency department of a hospital. This study will shed light on important factors contributing to service quality in emergency department of Indonesian public hospital by utilizing a cross-sectional design. About 117 patients were selected by simple random sampling techniques. Data observation sheets and a modified service quality instrument were used to measure health services in this department. Findings revealed that 83.8% patients felt satisfied with the services provided by emergency staff. Based on Kendall’s Tau test, waiting time had a significant relationship with service quality (p<0.05) compared to response time (p>0.05). The results of logistic regression test showed that waiting time had a higher value for Exp(B)= 3.522. In conclusion, waiting time was the most important factor affecting service quality in emergency department of Indonesian public hospital.
The anxiety symptoms among chronic kidney disease patients who undergo hemodialysis therapy
Authors: Rahman Shahrul , Pradido Rangga
Published: November 2020

Unresolved anxiety can lead to some impact on which a person tends to have a negative assessment of the meaning of life, decreased quality of life, emotional changes such as chronic depression and psychosis disorders. The general objective in this research is to find out the symptoms of anxiety symptoms of chronic kidney disease patients undergo hemodialysis. This research employed cross sectional design. This study used non-probability sampling type quota sampling. Sample was calculated using the Slovin formula obtained a sample size of 171. The proportion of patient with chronic kidney disease treated with hemodialysis based on the anxiety level resulting mild anxiety (86.5%) and moderate anxiety (13.5%). There are symptoms of anxiety symptoms in patients with chronic kidney disease undergoing hemodialysis.
Forward kinematic analysis of Dobot using closed-loop method
Authors: Sanjuan De Caro Javier Dario , Rahman Mohammad , Rulik Ivan
Published: November 2020

Dobot is a hybrid robot that combines features from parallel and serial robots. Because of this characteristic, the robot excels for is reliability, allowing its implementation in diverse applications. Therefore, researchers have studied its kinematics to improve its capabilities. However, to the extent of our knowledge, no analysis has been reported taking into consideration the closed-loop configuration of Dobot. Thus, this article presents the complete analytical solution for the forward kinematics of Dobot, considering each link. The results are expected to be utilized in the development of a dynamical model that contemplates the dynamics of each element of the robot.
A weighting system to build physical layer measurements maps by crowdsourcing data from smartphones
Authors: Alamleh Hosam , AlQahtani Ali Abdullah S.
Published: November 2020

Mobile devices can sense different types of radio signals. For example, broadcast signals. These broadcasted signals allow the device to establish a connection to the access point broadcasting it. Moreover, mobile devices can record different physical layer measurements. These measurements are an indication of the service quality at the point they were collected. These measurements data can be aggregated to form physical layer measurement maps. These maps are useful for several applications such as location fixing, navigation, access control, and evaluating network coverage and performance. Crowdsourcing can be an efficient way to create such maps. However, users in a crowdsourcing application tend to have different devices with different capabilities, which might impact the overall accuracy of the generated maps. In this paper, we propose a method to build physical layer measurements maps by crowdsourcing physical layer measurements, GPS locations, from participating mobile devices. The proposed system gives different weights to each data point provided by the participating devices based on the data source’s trustworthiness. Our tests showed that the different models of mobile devices return GPS location with different location accuracies. Consequently, when building the physical layer measurements maps our algorithm assigns a higher weight to data points coming from devices with higher GPS location accuracy. This allows accommodating a wide range of mobile devices with different capabilities in crowdsourcing applications. An experiment and a simulation were performed to test the proposed method. The results showed improvement in crowdsourced map accuracy when the proposed method is implemented.
Development of a real-time framework for farm monitoring using drone technology
Authors: Oyelami Adekunle T. , Akinade Adedayo S. , Obianefo Kingsley C.
Published: November 2020

This work developed a cost-effective framework for agriculturists to regularly monitor their crops against intruding rodents and other security concerns using modern drone technology through configuration and deployment of an autonomous UAV which also functions as a remotely piloted vehicle. This was done by configuring a quadcopter capable of causing a disturbance when a rodent is observed through an inbuilt alarm system whose sound is amplified to be loud enough to cause the animals to leave the farm area. A framework for real-time image and live video transmission from the farm to a designated remote base station was developed. This was achieved through programming codes that configured the drone to operate an intelligent alarm and object tracking systems which enables a live feed from the UAV using Arduino IDE and Mission Planner for autonomous flight control. The requisite algorithms were developed using the framework of tracking, learning and detection (TLD) in the OpenCV software. The drone movement is equally controlled remotely over a Wi-Fi network using an ESP8266 Wi-Fi module for redirection and controlling of the drone movement to monitor specific locations.
The algorithm of adaptive control for active suspension systems using pole assign and cascade design method
Authors: Van Chi Nguyen
Published: November 2020

This paper presents the active suspension system (ASS) control method using the adaptive cascade control scheme. The control scheme is implemented by two control loops, the inner control loop and outer control loop are designed respectively. The inner control loop uses the pole assignment method in order to move the poles of the original system to desired poles respect to the required performance of the suspension system. To design the controller in the inner loop, the model without the noise caused by the road profile and velocity of the car is used. The outer control loop then designed with an adaptive mechanism calculates the active control force to compensate for the vibrations caused by the road profile and velocity of the car. The control force is determined by the error between states of the reference model and states of suspension systems, the reference model is the model of closed-loop with inner control loop without the noise. The simulation results implemented by using the practice date of the road profile show that the capability of oscillation decrease for ASS is quite efficient
A simulated risk assessment of human-robot interaction in the domestic environment
Authors: Kaonain Tamanna E , Abdul Rahman Mohd Azizi , Mohammed Ariff Mohd Hatta , Mondal Kuheli
Published: November 2020

In human-robot interaction, the use of collaborative robots or cobots in many industries is of major importance to researchers in human-robot interaction (HRI). The interaction between human robot carries several challenges, the greatest being the risk of human injury. In addition to reducing the proximity between robots and humans, increased difficulty of human-robot encounters raises the likelihood of accidents only. This paper proposes a virtual collaborative robot in the simulated non-industrial workspace. The safety during human-robot interaction using simulation software was investigated by measuring the risks for planning and control. A reactive robot controller was formulated to minimize the risk during human-robot interaction. A Gazebo software is used in this article, written in Python language, to replicate complex environments that a robot can face. This paper also investigated the robot’s speed. It can be reduced before a collision with a human about to happen, and it minimized the risk of the collision or reduced the damage of the risk. After the successful simulation, this can be applied to the real robot in a practical domestic environment.
Amino Acid-Level Signal-to-Noise Analysis Aids in Pathogenicity Prediction of Incidentally Identified
TTN
-Encoded Titin Truncating Variants
Authors: Connell Patrick S. , Berkman Amy M. , Souder BriAnna M. , Pirozzi Elisa J. , Lovin Julia J. , Rosenfeld Jill A. , Liu Pengfei , Tunuguntla Hari , Allen Hugh D. , Denfield Susan W. , Kim Jeffrey J. , Landstrom Andrew P.
Published: November 2020

Background:

TTN
, the largest gene in the human body, encodes TTN (titin), a protein that plays key structural, developmental, and regulatory roles in skeletal and cardiac muscle. Variants in
TTN
, particularly truncating variants (TTNtvs), have been implicated in the pathogenicity of cardiomyopathy. Despite this link, there is also a high burden of TTNtvs in the ostensibly healthy general population. This complicates the diagnostic interpretation of incidentally identified TTNtvs, which are of increasing abundance given expanding clinical exome sequencing.

Methods:

Incidentally identified TTNtvs were obtained from a large referral database of clinical exome sequencing (Baylor Genetics) and compared with rare population variants from genome aggregation database and cardiomyopathy-associated variants from cohort studies in the literature. A subset of TTNtv-positive children evaluated for cardiomyopathy at Texas Children’s Hospital was retrospectively reviewed for clinical features of cardiomyopathy. Amino acid-level signal-to-noise analysis was performed.

Results:

Pathological hotspots were identified within the A-band and N-terminal I-band that closely correlated with regions of high percent-spliced in of exons. Incidental TTNtvs and population TTNtvs did not localize to these regions. Variants were reclassified based on current American College of Medical Genetics and Genomics criteria with incorporation of signal-to-noise analysis among Texas Children’s Hospital cases. Those reclassified as likely pathogenic or pathogenic were more likely to have evidence of cardiomyopathy on echocardiography than those reclassified as variants of unknown significance.

Conclusions:

Incidentally found TTNtvs are common among clinical exome sequencing referrals. Pathological hotspots within the A-band of TTN may be informative in determining variant pathogenicity when incorporated into current American College of Medical Genetics and Genomics guidelines.
New Concept of Onco-Hypertension and Future Perspectives
Authors: Kidoguchi Satoshi , Sugano Naoki , Tokudome Gorou , Yokoo Takashi , Yano Yuichiro , Hatake Kiyohiko , Nishiyama Akira
Published: November 2020

Owing to aging populations, the prevalence of hypertension and associated cardiovascular events has been increasing worldwide. The morbidity and mortality due to cancer have also been increasing with aging populations. Several small-molecule inhibitors have been used in cancer therapy, which have a positive impact on the prognosis and survival of patients with cancer. Consequently, the number of cancer survivors with hypertension has been rapidly increasing. Anticancer therapy, including vascular endothelial growth factor inhibitors, increases blood pressure. However, both clinical and laboratory evidence are lacking regarding optimal blood pressure control in patients with hypertension with cancer. Here, we propose the concept of onco-hypertension, which is an evolving subspecialty focused on the complex pathophysiology of hypertension and cancer. In this review, we highlight blood pressure changes in cancer, hypertension induced by anticancer therapy, and optimal blood pressure management in patients with hypertension with cancer. In addition, we discuss needed studies to further establish this new onco-hypertension concept.