bluuebunny/crossref_metadata_2025 huggingface dataset:
National Hospital-Based Sentinel Surveillance for Cholera in Bangladesh: Epidemiological Results from 2014 to 2021
Authors: Islam Md Taufiqul , Hegde Sonia Tara , Khan Ashraful Islam , Bhuiyan Md Taufiqur Rahman , Khan Zahid Hasan , Ahmmed Faisal , Begum Yasmina Ara , Afrad Mokibul Hassan , Amin Mohammad Ashraful , Tanvir Nabid Anjum , Khan Ishtiakul Islam , Habib Zakir Hossain , Alam Ahmed Nawsher , McMillan Nigel A. , Shirin Tahmina , Azman Andrew S. , Qadri Firdausi
Published: August 2023

Despite focusing on cholera burden, epidemiologic studies in Bangladesh tend to be limited in geographic scope. National-level cholera surveillance data can help inform cholera control strategies and assess the effectiveness of preventive measures. Hospital-based sentinel surveillance among patients with suspected diarrhea in different sites across Bangladesh has been conducted since 2014. We selected an age-stratified sample of 20 suspected cholera cases each week from each sentinel site, tested stool for the presence of Vibrio cholerae O1/O139 by culture, and characterized antibiotic susceptibility in a subset of culture-positive isolates. We estimated the odds of being culture positive among suspected cholera cases according to different potential risk factors. From May 4, 2014 through November 30, 2021, we enrolled 51,414 suspected cases from our sentinel surveillance sites. We confirmed V. cholerae O1 in 5.2% of suspected cases through microbiological culture. The highest proportion of confirmed cholera cases was from Chittagong (9.7%) and the lowest was from Rangpur Division (0.9%). Age, number of purges, duration of diarrhea, occupation, and season were the most relevant factors in distinguishing cholera-positive suspected cases from cholera-negative suspected cases. Nationwide surveillance data show that cholera is circulating in Bangladesh and the southern region is more affected than the northern region. Antimicrobial resistance patterns indicate that multidrug resistance (resistance to three or more classes of antibiotics) of V. cholerae O1 could be a major threat in the future. Alignment of these results with Bangladesh’s cholera-control program will be the foundation for future research into the efficacy of cholera-control initiatives.
The Human Mpox Global Outbreak: Available Control Tools and the Opportunity to Break a Cycle of Neglect in Endemic Countries
Authors: Nachega Jean B. , Mbala-Kingebeni Placide , Rosenthal Philip J. , Rimoin Anne W. , Hoff Nicole A. , Liesenborghs Laurens , Vanlerberghe Veerle , Andrei Graciela , Rawat Angeli , Wilson Lindsay A. , Forrest Jamie , Mills Edward J. , Hermans Michel P. , Mulangu Sabue , Ntoumi Francine , Zumla Alimuddin , Muyembe-Tamfum Jean-Jacques
Published: August 2023

The 2022 global outbreak of human Mpox (formerly monkeypox) virus (MPXV) infection outside of the usual endemic zones in Africa challenged our understanding of the virus’s natural history, transmission dynamics, and risk factors. This outbreak has highlighted the need for diagnostics, vaccines, therapeutics, and implementation research, all of which require more substantial investments in equitable collaborative partnerships. Global multidisciplinary networks need to tackle MPXV and other neglected emerging and reemerging zoonotic pathogens to address them locally and prevent or quickly control their worldwide spread. Political endorsement from individual countries and financial commitments to maintain control efforts will be essential for long-term sustainability.
Performance of SARS COV-2 IgG Anti-N as an Independent Marker of Exposure to SARS COV-2 in an Unvaccinated West African Population
Authors: Abdullahi Adam , Frimpong James , Cheng Mark T. K. , Aliyu Sani H. , Smith Colette , Abimiku Alash’le , Phillips Richard Odame , Owusu Michael , Gupta Ravindra K.
Published: August 2023

Determination of previous SARS-COV-2 infection is hampered by the absence of a standardized test. The marker used to assess previous exposure is IgG antibody to the nucleocapsid (IgG anti-N), although it is known to wane quickly from peripheral blood. The accuracies of seven antibody tests (virus neutralization test, IgG anti-N, IgG anti-spike [anti-S], IgG anti–receptor binding domain [anti-RBD], IgG anti-N + anti-RBD, IgG anti-N + anti-S, and IgG anti-S + anti-RBD), either singly or in combination, were evaluated on 502 cryopreserved serum samples collected before the COVID-19 vaccination rollout in Kumasi, Ghana. The accuracy of each index test was measured using a composite reference standard based on a combination of neutralization test and IgG anti-N antibody tests. According to the composite reference, 262 participants were previously exposed; the most sensitive test was the virus neutralization test, with 95.4% sensitivity (95% CI: 93.6–97.3), followed by 79.0% for IgG anti-N + anti-S (95% CI: 76.3–83.3). The most specific tests were virus neutralization and IgG anti-N, both with 100% specificity. Viral neutralization and IgG anti-N + anti-S were the overall most accurate tests, with specificity/sensitivity of 100/95.2% and 79.0/92.1%, respectively. Our findings indicate that IgG anti-N alone is an inadequate marker of prior exposure to SARS COV-2 in this population. Virus neutralization assay appears to be the most accurate assay in discerning prior infection. A combination of IgG anti-N and IgG anti-S is also accurate and suited for assessment of SARS COV-2 exposure in low-resource settings.
Update on the Geographic Distribution of the Intermediate Host Snails of Schistosoma mansoni on St. Lucia: A Step Toward Confirming the Interruption of Transmission of Human Schistosomiasis
Authors: Mukaratirwa Samson , Laidemitt Martina R. , Hewitt Reynold , Sengupta Mita E. , Marchi Silvia , Polius Consortia , Belmar Sharon , Scholte Ronaldo G. C. , Perez Freddy , Stensgaard Anna-Sofie , Vennervald Birgitte J. , Willingham Arve L. , Loker Eric S.
Published: August 2023

To provide information to guide considerations of declaring interruption of transmission of human schistosomiasis due to Schistosoma mansoni on St. Lucia, we undertook an island-wide survey in June–July 2022 to determine the presence of Biomphalaria snails, the intermediate hosts of S. mansoni, and their infection status. Snail surveys were carried out at 58 habitats to determine presence of Biomphalaria snails followed by examination of the collected snails for evidence of infection with S. mansoni. Furthermore, water samples were collected at the snail habitats and screened for presence of S. mansoni DNA using an eDNA approach. We found B. glabrata present in one habitat (Cul de Sac) where it was abundant. Specimens provisionally identified as Biomphalaria kuhniana were recovered from 10 habitats. None of the Biomphalaria specimens recovered were positive for S. mansoni. None of the eDNA water samples screened were positive for S. mansoni. Experimental exposures of both field-derived and laboratory-reared St. Lucian B. glabrata and B. kuhniana to Puerto Rican and Kenyan-derived S. mansoni strains revealed B. glabrata to be susceptible to both and B. kuhniana proved refractory from histological and snail shedding results. We conclude, given the current rarity of B. glabrata on the island and lack of evidence for the presence of S. mansoni, that transmission is unlikely to be ongoing. Coupled with negative results from recent human serological surveys, and implementation of improved sanitation and provision of safe water supplies, St. Lucia should be considered a candidate for declaration of interruption of human schistosomiasis transmission.
HASIL KARYA CIPTA LAGU ANAK-ANAK
Authors: Samsuri Samsuri , Astuti Yuli
Published: August 2023

The research entitled “The Creative work of Children’s Songs”. Raising the problem in this research is how to create children’s songs for elementary school level? This study aims to describe the process of creating songs for children at the elementary school level. The approach used in this research is a qualitative approach with a descriptive type of research. The subjects in this study were elementary school children at the high level, namely grades are IV-VI. While the object to be studied was a song entitled Ayah Bunda which was created by the researcher. The data in this studi were collected using literature study, observation, and documentary. From the results of the study, it showed that elementary school children in high grade were able to sing a song created by researcher entitled Ayah Bunda with a range of tones that were appropriate for their age. The lyris of the song were created according to the age of the children, which is about the happiness of children when they are loved and pampered by their parents. As a feeling of gratitude and gratitude, children should always pray for their parents so that they live long and always be healthy.

Abstrak

Penelitian yang berjudul “Hasil Karya Cipta Lagu Anak-Anak”. Mengangkat masalah dalam penelitian ini adalah bagaimana hasil karya cipta lagu anak-anak untuk tingkat sekolah dasar?. Penelitian ini bertujuan untuk mendeskripsikan proses penciptaan lagu untuk usia anak-anak pada tingkat sekolah dasar. Pendekatan yang digunakan dalam penelitian ini adalah pendekatan kualitatif dengan jenis penelitian deskriptif. Subjek dalam penelitian ini yaitu anak-anak sekolah dasar pada tingkat kelas tinggi yaitu kelas IV-VI), sedangkan Objek yang akan diteliti yaitu lagu yang berjudul Ayah Bunda hasil ciptaan peneliti. Data pada penelitian ini dikumpulkan dengan teknik studi pustaka, observasi dan dokumentasi. Dari hasil penelitian menunjukkan bahwasanya, anak-anak sekolah dasar kelas tinggi mampu menyanyikan lagu hasil ciptaan peneliti yang berjudul Ayah Bunda dengan jangkauan nada yang sesuai dengan usia mereka. Lirik lagu yang diciptakan sesuai dengan usia anak-anak yaitu berisi tentang kebahagian anak-anak saat disayang dan dimanjakan oleh kedua orang tuanya. Sebagai rasa bersyukur dan terimakasih, anak-anak sudah sepatutnya selalu mendoakan ayah bundanya agar panjang umur dan sehat selalu.
ANALISIS KESALAHAN AFIKSASI DAN EJAAN PADA ARTIKEL BERITA DI MEDIA MASSA ONLINE HARIANE.COM EDISI SEPTEMBER 2022
Authors: Utami Dewi Wahyu , Lestari Wahyu Fajar , Kusnasari Zanida Zulfana , Ulya Chafit
Published: August 2023

Salah satu kesalahan yang sering ditemukan dalam tataran morfologi adalah kesalahan afiksasi dan ketidaktepatan ejaan. Kesalahan-kesalahan bahasa tersebut seringkali membuat pembaca salah menafsirkan dan menyebabkan ungkapan penulis tidak dapat tersampaikan dengan baik. Penelitian ini menggunakan dan menerapkan metode penelitian deskriptif kualitatif. Penelitian kualitatif adalah metode penelitian yang membahas fenomena sosial, budaya, dan tingkah laku manusia. Tahapan penelitian kualitatif dimulai dengan memilih objek penelitian yaitu surat kabar online Hariane.com edisi September. Kemudian dilanjutkan dengan pengumpulan data berkaitan dengan objek penelitian. Setelah data diperoleh, tahap berikutnya adalah menyusun catatan data dan menganalisisnya. Ditemukan beberapa kesalahan pada tataran morfologi dalam media massa online Hariane.com edisi September 2022. Kesalahan yang ditemukan berupa peluluhan afiks dan penghilangan afiks. Banyak ditemukan kesalahan penulisan kata baku dan preposisi dalam tataran ejaan. Penelitian ini bertujuan mencari kesalahan pemakaian afiksasi dan ejaan yang sering ditemukan pada media massa serta memperbaikinya. Penelitian selanjutnya diharapkan dapat memilih topik dan mengkaji lebih dalam lagi mengenai penyebab kesalahan pada tataran morfologi (khususnya afiksasi) dan ejaan.
MODEL PEMBELAJARAN PROBLEM BASED LEARNING DALAM MENGEMBANGKAN KETERAMPILAN PEMAHAMAN MEMBACA META-KOGNITIF MAHASISWA
Authors: Verawati Verawati , Syarfuni Syarfuni
Published: August 2023

Tujuan utama dari penelitian ini adalah untuk mengembangkan pemahaman membaca metakognitif mahasiswa menggunakan model pembelajaran problem based learning. Subjek penelitian adalah 30 mahasiswa di Akademi Farmasi Mandiri YPPM. Penelitian ini menggunakan desain kuasi-eksperimental dengan satu kelompok. Hasil penelitian ini menunjukkan bahwa mahasiswa memiliki keterampilan membaca pemahaman yang meliputi menebak, mendeskripsikan, menganalisis dan mengidentifikasi gagasan utama. Dengan demikian, model pembelajaran yang dirancang dan digunakan untuk mengembangkan keterampilan membaca pemahaman meta-kognitif. Temuan penelitian ini menunjukkan bahwa ada perbedaan statistik antara nilai rata-rata siswa pada pretest dan posttest, dan ada perbedaan statistik antara nilai rata-rata siswa pada posttest pada level 0,05. Hal ini dapat disimpulkan bahwa Model pembelajarn PBL dapat mengembangkan keterampilan membaca pemahaman metakognitif mahasiswa.
PENGARUH PENERAPAN MODEL PJBL (PROJECT-BASED LEARNING) TERHADAP KETERAMPILAN ABAD 21
Authors: Undari Mayrisa , Darmansyah  , Desyandri
Published: August 2023

Abstrak

Penelitian ini bertujuan membahas bagaimana pengaruh penerapan model PjBL (Project-Based Learning) terhadap keterampilan abad 21 yang mencakup Critical Thinking, Communication, Creative Thinking, dan Collaboration yang sering disebut keterampilan 4C. Jenis penelitian ini kualitatif deskriptif dengan metode systematic literature review yang terdiri dari beberapa taha. Pertama  planning, dimana kita menentukan topik yang akan dibahas, penetapan kriteria artikel yang akan digunakan. Kedua Conducting, proses mencari, memilih artikel dan sintesis data. Ketiga reporting, penulisan hasil systematic literature review. Berdasarkan kajian 17 artikel nasional, penerapan model PjBL merupakan upaya yang banyak dilakukan untuk meningkatkan keterampilan  abad 21. Hasil penelitian yang dilakukan dapat diketahui bahwa penggunaan model PjBL dapat meningkatkan keterampilan abad 21 yang mencakup kemampuan berfikir kritis, komunikasi, kreatifitas dan kolaborasi. 

Abstract

This study aims to discuss how the influence of the application of the PjBL (Project-Based Learning) model has on 21st century skills which include Critical Thinking, Communication, Creative Thinking, and Collaboration which are often called 4C skills. Type study this qualitative descriptive with method a systematic literature review consisting of from a number of haha . First  planning , where our determine topic to be discussed , determined criteria article to be used . Second Conducting, process of searching , choosing article and data synthesis . Third reporting , writing results systematic literature review . Based on review of 17 articles national level , implementation of the PjBL model is lot of effort conducted for increase Skills  21st century . Results research conducted _ could is known that use of the PjBL model could increase Skills 21st century that includes ability think critical , communication , creativity and collaboration .
PENGEMBANGAN LKPD MEMBACA PERMULAAN BERBASIS PERMAINAN KATA DENGAN MENGGUNAKAN METODE SAS PADA KELAS I SEKOLAH DASAR
Authors: Karima Melda , Murniviyanti Liza , Prasrihamni Mega
Published: August 2023

This study aims to produce a product in the form of Student Worksheets based on word games using the Structural Analytical Synthetic method. This Research and Development uses the Analysis, Design, Development, Implementation, Evaluation (ADDIE) model. The trial was conducted at SD Negeri 20 Banyuasin I with data collection techniques in the form of interviews, questionnaires (questionnaires) and documentation. The results of the research and development that have been carried out show that: the validation assessment by material experts, linguists and media experts gets a score of 84.74 with a very valid category; the assessment of the teacher and student questionnaires got a score of 84.34 with a very practical category; the pretest and posttest assessments of students obtained 0.74 from the results of the n-gain calculation with a high category which means it is very effective. It was concluded that the Student Worksheet reading the beginning based on word games using the SAS method in grade I Elementary School was very valid, practical and effective and feasible to use.

Abstrak

Penelitian ini bertujuan untuk menghasilkan produk berupa Lembar Kerja Peserta Didik membaca permulaan berbasis permainan kata dengan menggunakan metode Struktural Analitik Sintetik. Penelitian dan Pengembangan (Research and Development) ini menggunakan model Analisis, Desain, Pengembangan, Penerapan, Evaluasi (ADDIE). Uji coba dilakukan di SD Negeri 20 Banyuasin I dengan teknik pengumpulan data berupa wawancara, angket (kuesioner) dan dokumentasi. Hasil dari penelitian dan pengembangan yang telah dilaksanakan menunjukkan bahwa: penilaian validasi oleh ahli materi, ahli bahasa dan media mendapatkan skor 84,74 dengan kategori sangat valid; penilaian angket guru dan peserta didik mendapatkan skor 84,34 dengan kategori sangat praktis; penilaian pretest dan posttest peserta didik diperoleh 0,74 dari hasil perhitungan n-gain dengan kategori tinggi yang berarti sangat efektif. Disimpulkan bahwa Lembar Kerja Peserta Didik membaca permulaan berbasis permainan kata dengan menggunakan metode SAS pada kelas I Sekolah Dasar ini sangat valid, praktis dan efektif serta layak untuk digunakan.
Augmented Reality for Teaching Storytelling in a Rural Foundation Phase Primary School: Integrating a Place-Based Approach
Authors: Mpiti Pretty Thandiswa , Makena Bulelwa , Qoyi Motsi
Published: August 2023

Augmented reality (AR) has recently become a new leading edge in mobile-assisted language learning attributed to the popularity of smartphones. The place-based approach (PBA) is a situated, context-rich teaching and learning modality characterized by its relationship to place. AR and PBA have proven to be useful in educational settings; however, few studies have observed them being used jointly. This study aims to explore the combination of AR and PBA in teaching storytelling in a foundation phase (FP) rural primary school. Based on current trends, the study also aims to design learning principles for teaching that will help language teachers integrate this innovative technology and approach into literacy teaching. The study was tested with two FP teachers and 12 FP learners in a real classroom and carried out with qualitative observations and semi-structured interviews. The findings reveal that learners are more motivated and interested in activities that have been enhanced because they encourage problem-solving, discovery, and socialization. The findings also suggest that technological interventions, particularly when learners work as a team, may have a bigger impact than non-technology-integrated instruction. These results offer demonstrable support for technology use and have useful results for future practice.
Trends and Challenges of Formal Agricultural Credit in Bangladesh: Enhancing Productivity and Promoting Inclusive Growth
Authors: Sultana Nurun Nahar , Hossain Md. Nabir
Published: August 2023

Empirical studies provide evidence that agricultural finance is crucial for agriculture structural development of an economy. Ensuring the productivity of the agricultural sector is crucially important for the timely availability of agricultural credit. The purpose of this study is to look at what is going on with agricultural credit, especially in the formal sector of banking. Throughout the years, there has been a significant increase in credit disbursed through the official sector, which includes commercial banks and other financial institutions. This is a significant development, as in the past the informal sector was dominant. Non-Governmental Organizations (NGOs), private commercial banks in the area, and foreign banks have all played a role in the provision of agricultural credit to farmers throughout the country. However, despite the increasing flow of credit from formal sector institutions, some challenges need to be addressed. Accessibility remains a concern, particularly for small and marginalized farmers who struggle to access formal credit channels. For formal agricultural credit to have a positive impact, it is necessary to ensure its widespread availability, to provide financial products that are tailored to the needs of farmers, and to implement policies that reduce inefficiency and leakages in the distribution of credit. By addressing these challenges, formal agricultural credit can play a pivotal role in enhancing agricultural productivity, empowering farmers, and driving sustainable economic growth in Bangladesh.
Good Governance and Public Administration in a Post-Pandemic Era
Authors: Rosenbaum Allan
Published: August 2023

COVID-19 has resulted in severe economic hardships globally, calling into attention the key issue of growing inequalities between the rich and the poor. Without significant policy adjustments, the degree of inequality in terms of wealth and income would continue to worsen. This chapter calls upon authors and practitioners of public administration to critically examine the worsening wealth and income inequalities around the globe and, in doing so, strengthen and reform the processes of governance to make societies fairer and more equitable.
Assessing Policy Response against COVID-19: Bhilwara Model in India
Authors: Meena Ekta
Published: August 2023

The sudden spread of the COVID-19 pandemic not only affected the health system of a nation but also widely impacted the economic, political, and social aspects of citizens. Its effect could be seen in every nation. India, having an estimated population of 1.39 billion which is just below China’s, faced the worst of its effect. It gave a jolt to the legislature for their health policies, which led to the administration trying new governance models. COVID-19 has exposed the legal awareness, or lack thereof, of governments of how to mitigate and control its impact. All 28 states of India worked in the best possible ways to control and mitigate the spread of virus. In such a scenario one model that came out of the box was the Bhilwara Model of Rajasthan, which has been popularised for its immediate administrative effectiveness to curb the COVID-19 during the first wave. The purpose of this chapter is to highlight the existing governmental measures for health emergencies in the Indian state of Rajasthan and to attempt to identify the gaps in the legislative provisions. Based on the analysis, this chapter makes several suggestions for amendments to existing legislation and recommends the promotion of comprehensive public health legislation.
Agenda Setting Towards Residential Land Use Policy in the Context of Health Emergencies: The Case of Barangay Guadalupe, Cebu City, Philippines
Authors: Eata Earl Max , Abragan Clyde Cedrick , Miralles Kendrick William , Aliganga Junpaolo , Dungog-Cuizon Ana Leah
Published: August 2023

It is indubitable that land use and urban residential designs significantly affect the exposure of urban residents and other stakeholders to hazards in times of health emergencies, particularly amidst the COVID- 19 pandemic. Most importantly, this is so if there is no recent Land Use Plan by the city government or when such is not on its priority agenda. This study delved into the process of agenda-setting concerning residential land use amidst the pandemic, using the case of Barangay Guadalupe, Cebu City in the Central Philippines, highlighting the socio-political dynamics of stakeholders, namely, the residents, the local government, businesses, and involved civil society groups. Thematic analysis was utilised, revealing central and critical themes that constitute the level of involvement in the agenda-setting, the problems encountered, and the effects of the residential land use policy on the stakeholders in the context of the COVID-19 pandemic. The study found that there is a large gap between stakeholders in the level of involvement in the agenda setting, thereby leading to problems and challenges that are economic, political, and socio-cultural. The researchers recommend enhanced and inclusive multi-sectoral consultations and stakeholder involvement; allowing active participation and collaboration in the agenda setting towards an effective residential land use policy is mandatory under the land space of the pandemic.
Paraguassu e A Independência do Brasil: dois momentos da épica romântica brasileira
Authors: Silva Anazildo
Published: August 2023

Este artigo se propõe a refletir criticamente sobre as epopeias Paraguassu (1835-1837), de Ladislau dos Santos Titara e A Independência do Brasil (1847-1855), de Teixeira e Sousa, a partir do conceito “modelo épico romântico” e dos desdobramentos que a poesia épica teve no Brasil em seu momento estético romântico. A abordagem leva em consideração a presença dos planos histórico e maravilhoso das obras e os recursos épicos utilizados pelos autores no plano literário de cada uma, com destaque para a emulação épica. Ressalta-se que as duas epopeias são pouco conhecidas pelo público leitor, o que motivou citações de partes fundamentais para a compreensão das duas propostas.
Long-term outcomes of isolated limb perfusion with hyperthermia in patients with soft tissue sarcomas
Authors: Kharatishvili T. K. , Petrochenko N. S. , Gribkova E. I. , Buidenok Yu.  V. , Kaspshik S. M. , Aliyev M. D.
Published: August 2023

In case of locally advanced soft tissue sarcomas of the extremities (STS), the large size of which does not allow resection with preservation of the limb, isolated regional perfusion (IRP) of the limb is considered as one of the effective treatment options.

Aim. To evaluate the long-term outcomes of IRP with melphalan under conditions of hyperthermia for treatment of locally advanced STS of the extremities.

Materials and methods. We conducted a prospective cohort clinical study that included 42 patients with STS of the extremities. All patients underwent IRP with melphalan, in one case – in combination with tumor necrosis factor alpha. Additional lymph node dissection was performed in 8 cases (19%). The 5-year overall survival was estimated by the Kaplan-Meier method.

Results. The median age of the patients was 50 years (from 24 to 80 years), women predominated – 32 (76%). STS of the upper limb was diagnosed in 14 patients (33%), of the lower limb in 28 (67%). G3 grade was verified in 34 (81%) patients, in the rest – G2. Most patients had a recurrent tumor – in 34 (81%) cases. All patients received previous treatment: surgery in combination with chemotherapy and / or radiation therapy – 36 (86%), chemotherapy alone – 2 (5%), surgery alone – 4 (9%) patients. Within 5 years, tumor recurrence developed in 20 (48%) patients, amputation was performed in 10 (24%) patients, distant metastases were diagnosed in 4 (10%) patients. The mean time to relapse after IPC was 9.3 ± 3.5 months. Overall survival at 1, 2, 3, 4, and 5 years was 98%, 88%, 86%, 74%, and 67%, respectively.

Conclusion. IRP under conditions of hyperthermia with melphalan is an effective method for the treatment of STS of the extremities: the overall 5-year survival rate is 67% with a low rate of amputations and metastasis.
Effects of Selenium Biofortification on Phytochemical Characteristics of Some Table Grape Cultivars
Authors: SUCU Seda , TOPCU ALTINCI Neval , YAĞCI Adem , KILIÇ Duran , ŞAHİN Sezer , CANGİ Rüstem
Published: August 2023

Table grapes, rich in vitamins and minerals, play an important role in human nutrition, thus largely used in daily diets. Selenium (Se) with positive impacts on human health and anticancerogenic effects, has recently become prominent in human nutrition and animal feeding. In this study, selenium fortifications were made at different doses (control, 4 ppm and 8 ppm) to 9 different table grape cultivars (Alphonse Lavallée, Bilecik İrikarası, Cardinal, Sultani Seedless, Tekirdağ Seedless, Italia, Lival, Victoria, Royal) and total phenolics, anthocyanins and flavonoids of the cultivars were determined. While total phenolics of the whole berry was presented, skin and pulp total anthocyanins and total flavonoids were presented separately. The greatest total phenolic amount was obtained from 4 ppm selenium treatment in Bilecik İrikara (157.31 mg/g) cultivar. The greatest total anthocyanin contents were obtained from the skin of with 8 ppm selenium treatment in Alphonse Lavallée (11.22 mg/g). Selenium treatments increased total flavonoids of Bilecik İrikarası, Lival, Royal and Sultani Seedless cultivars. It was concluded based on findings that Se treatments influenced phytochemical characteristics of the table grapes.
DUKUNGAN KELUARGA BERHUBUNGAN DENGAN TERHADAP TAHAPAN BERDUKA ( STAGE OF GRIEFING ) PASIEN DIABETES MELITUS DI PUSKESMAS SENDURO LUMAJANG
Authors: Kurnia Agung Yoga Sandhi
Published: August 2023

Seseorang yang menderita penyakit Diabetes Melitus dapat mengalami reaksi berupa perubahan biologi, psikologi, sosial,reaksi ini akan berakibat penurunan kwalitas kesehatan yang akan menambah memperburuknya keadaan kesehatanya,untuk itu masalah yang diderita selain diabets adalah perubahan tahapan berduka,respon tahapan ini sangat mempengaruhi penerimaan terhadap penyakit ini, penelitian ini bertujuan untuk mengetahui hubungan dukungan keluarga terhadap tahapan berduka (stage of griefing)pasien diabetes militus di Puskesmas Senduro Lumajang.

Jenis penelitian ini menggunakan metode “analitik korelasional” dengan desain penelitian cross sectional,sampel penelitian ini diambil dengan metode Accident Sampling dengan populasi  79 pasien dan sampel 66 pasien diabetes militus.responden di dapat dipoli umum puskesmas senduro lumajang,yang dilaksanakan pada tanggal 27 Februari 2023 – 20 Maret 2023.Dengan menggunakan kuisoner Hensarling Diabetes Family Support Scale (HDFSS) dan the acceptance of disease and impairment (ADIQ) yang telah di validasi dan reabilitasi. serta dianalisis menggunakan SPSS dengan uji rank spearman rho

Data didapat,dengan hasil penelitian menunjukan dukungan keluarga sebanyak 41 (62.1%) responden,sedangkan pada tahapan berduka di fase penerimaan sebanyak 45 (68,2%) responden hasil penelitian menunjukan dukungan keluarga terhadap tahapan berduka (stage of griefing) pasien diabetes militus dengan nilai (p-value 0,000) dengan nilai correlation coefficient sebesar (+0.867).

Seseorang yang telah terdiagnosis penyakit diabetes dapat mengalami berbagai tahapan berduka selama hudupnya. keluarga menjadi support sistem bagi pasien diabetes militus dan untuk instansi pemerintah bisa sebagai bahan pertimbangan  pelayanan dan pengembangan program peningkatan peran keluarga dalam upaya menangani tahapan berduka penderita yang pasti akan dialami,sehingga bisa meningkatkan derajat kesehatan penderita yang berkelanjutan.
Asuhan Keperawatan pada Pasien Halusinasi Pendengaran dengan Penerapan Terapi Generalis
Authors: Arni Nur Rahmawati  , Luthfiana Dewi
Published: August 2023

Introduction: Halusinasi pendengaran merupakan distorsi persepsi palsu dimana pasien gangguan jiwa mendengar bisikan atau suara-suara yang tidak nyata dan meresponnya. Gangguan halusinasi dapat dikontrol dengan terapi generalis SP 1-4: mengenalkan halusinasi dan menghardik, minum obat, bercakap-cakap dan melakukan aktivitas terstruktur.

Objectives:  Tujuan penelitian ini adalah untuk memberikan asuhan keperawatan pada pasien dengan gangguan persepsi sensori: halusinasi pendengaran.

Methods: Metode yang digunakan adalah studi kasus melalui wawancara, observasi fisik dan dokumentasi. Partisipan yang digunakan dalam implementasi asuhan keperawatan jiwa adalah Sdr. A dengan gangguan halusinasi pendengaran di Wisma Antareja RSJ Prof. Dr. Soerojo Magelang. Analisis data yang digunakan dengan melakukan evaluasi penerapan generalis strategi pelaksanaan halusinasi.

Results:  Hasil studi kasus menunjukkan bahwa pasien mampu mengidentifikasi masalah halusinasi yang dialami dan mampu mengontrol halusinasi.

Conclusions: Terapi generalis pada pasien halusinasi dapat membantu pasien mengenali halusinasinya sampai pada tindakan mengontrol halusinasi. Terapi generalis sebaiknya dilakukan rutin oleh perawat kepada pasien.
Proposed Human Capital Management Strategy to Improve Elementary School Teachers’ Competencies in Rahuning, North Sumatra, Indonesia (Case Study of SDIT Ar-Rahmah)
Authors:   Master of Business Administration, Institut Teknologi Bandung, Annur Fauziyah , Febriansyah Hary ,   Master of Business Administration, Institut Teknologi Bandung
Published: August 2023

The issue of low teacher competence in Indonesian schools outside of the big cities requires solutions from the outside and inside of the school. From within the organization, Human Capital Management (HCM) provides a beneficial framework for improving teachers’ competence and overall school quality. This study aims to understand the low competency issues and the HCM system in Ar-Rahmah Rahuning Integrated Islamic Elementary School (SDIT Ar-Rahmah) and formulates competency development programs using Lifelong Learning (LLL) approach. In this mixed method research, a survey conducted on teachers’ competency in SDIT Ar-Rahmah using the Teacher’s Competence model outlined by the Director General of Teachers and Education Personnel in 2023 to evaluate four teacher’s primary competence (pedagogic, personal, social, and professional competence), followed by a qualitative study on the HCM system, focusing on the competency development program. The study reveals that the average teachers in SDIT Ar-Rahmah indicate the need to improve pedagogic and social competence. Further, the HCM system in SDIT Ar-Rahmah lacks Professional Development and Performance Management for its teachers. The HCM system is highly reliant on the School Principal, which causes issues in developing Professional Development and Performance Management. A competency development program is formulated using Lifelong Learning approach to ensure continuous improvement throughout the teachers’ employment. The program focuses on six key elements: 1) formal and nonformal education, 2) introspection and self-assessment, 3) self-motivated learning, 4) application of knowledge and skills, 5) evaluation and improvement steps, and 6) provision of facilities and tools that foster Lifelong Learning habits.
O glúten como temática para o ensino de química
Authors:   , Varotto Gisele de Cássia
Published: August 2023

O ensino de química não pode mais ser pautado em memorização de dados e fórmulas. Faz-se necessário dar aplicabilidade para o que se estuda, através da integração dos conhecimentos químicos com o cotidiano. A proposta deste trabalho é apresentar os conceitos químicos de forma contextualizada, objetivando a preparação do indivíduo para o autocuidado e o cuidado com o outro, a partir dos distúrbios alimentares relacionados à ingestão de glúten. A decisão de se fazer um trabalho voltado para o glúten e os problemas de saúde relacionados a ingestão do mesmo foi tomada tendo em vista o crescente número de pessoas acometidas pela intolerância ou alergia alimentar, muitas delas ainda em idade escolar. Aliado ao despreparo das escolas para lidar com essa situação, embora prevista em legislação específica, está o desconhecimento da sociedade sobre esse assunto e a consequente exclusão do aluno com necessidades alimentares especiais. A proposta de desenvolvimento do tema foi elaborar um produto educacional com uma sequência temática integrada aos tópicos curriculares da química do ensino médio juntamente com a disciplina de práticas comunicativas e criativas dentro da temática saúde integral, buscando apresentar esclarecimentos sobre o glúten e ainda, a disponibilização de um e-book de receitas com farinhas livres de glúten. Palavras-chave: Glúten. Alergia alimentar. Inclusão alimentar. Ensino de química.
Síndrome de Williams-Beuren y la importancia del diagnóstico oportuno. Reporte de caso
Authors: Pinta-Paguatián Ana Ximena , Patiño-Ortega Oscar Mauricio , Portillo-Miño José Darío
Published: August 2023

Objetivo: Se presenta un paciente con Síndrome de Williams-Beuren (SWB) con manifestaciones clínicas en el primer año de vida, resaltando la disfunción cognitiva/retraso global, alteraciones cardiovasculares y faciales como elementos clave para fomentar la sospecha clínica y la importancia del diagnóstico oportuno con el fin de disminuir la morbilidad y mortalidad del paciente.
Descripción del caso: Paciente masculino de 12 meses de edad, producto de segunda gestación, cesárea a las 37,5 semanas, peso al nacer: 2400 g, talla 47 cm y perímetro cefálico 34 cm. Asiste a cita de control con pediatría a los 3 meses de edad donde se observa dacrioestenosis, dificultad para alimentarse y dismorfias faciales menores. En los antecedentes familiares; padres jóvenes, sin historial de enfermedades genéticas, no consanguíneos, el resto de antecedentes sin relevancia clínica. Se realizó seguimiento por 12 meses debido a la severidad y presentación inusual de algunas manifestaciones clínicas que ocurren en fases tardías.
Conclusiones: El SWB ha sido descrito por sus manifestaciones clínicas variables, sin embargo, su identificación e intervención multidisciplinaria es oportuna al conocerse las alteraciones multisistémicas de acuerdo a la edad. El SWB debe considerarse dentro de los diagnósticos diferenciales en pacientes pediátricos con retraso del desarrollo psicomotor, anomalías cardiovasculares severas y/o dimorfismos faciales ya que desempeñan un rol clave en la sospecha clínica de esta patología, reduciendo el gasto de los recursos del sistema de salud y mejorando la calidad de vida del paciente de acuerdo a sus necesidades.
Síndrome de Body Stalk. Reporte de caso.
Authors: Hoyos-Belalcázar Diana Marcela , Quilindo Catalina Isabel , Narvaez-Chávez John Edgar
Published: August 2023

Objetivo: Reportar un caso de síndrome de Body Stalk en una gestante con antecedente de consumo de sustancias psicoactivas y sífilis gestacional.

Descripción de caso: Presentamos un caso de síndrome de Body Stalk diagnosticado a las 10 semanas de edad gestacional. El embrión presentaba múltiples defectos característicos del síndrome, incluyendo defectos de la pared abdominal y de extremidades inferiores. El síndrome de Body Stalk es un defecto congénito poco frecuente con mal pronóstico.

Conclusiones: El síndrome de Body Stalk es un defecto congénito severo el cual es incompatible con la vida. El diagnóstico prenatal ultrasonográfico ayuda a definir la conducta obstétrica y disminuye el riesgo de morbilidad materna.
Educación, ciencia y responsabilidad.
Authors: Jaramillo-Echeverri Luis Guillermo
Published: August 2023

En el año 1998, el Dr. Bernardo Restrepo Gómez, miembro en ese entonces del Concejo Nacional de Acreditación –CNA–, esgrimía que desde 1994 el Ministerio de Educación Nacional veía con preocupación que de los 4.000 programas de Educación Superior existentes en el país se había pasado a 20.000 en menos de 4 años. Es decir, aumentaron programas de Educación a Distancia ofrecidos como cursos de extensión, regionalización; programas virtuales y de presencialidad concentrada estaban funcionando en casonas viejas, oficinas alquiladas los fines de semana, hoteles, y demás estructuras que desdecían mucho de su calidad académica. En vista de lo anterior, el CNA dispuso de normas para el cumplimiento de la acreditación de estos programas, a fin de que estos posean los mínimos estándares de calidad, así como el tipo de formación en ciencia e investigación que imparten.
Dermatitis atópica en pacientes hermanas: caso clínico y consideraciones sobre consanguinidad en dermatitis atópica
Authors: Posso-Garcia Gustavo Antonio , Flórez-Hurtado Johan , Hernández-Zuluaga Germán Darío
Published: August 2023

Objetivo: En el presente reporte de caso, se discute la diferencia de presentación clínica en dos hermanas afectadas por dermatitis atópica y se hace una breve revisión de la literatura respecto a la asociación existente entre hermanos y los factores que pueden influir en las características y evolución de la enfermedad en pacientes con dermatitis atópica.
Descripción breve del caso: Se describe la presentación de dermatitis atópica en dos pacientes hermanas que debutan con una severidad de enfermedad parecida, pero levemente mayor y con evolución distinta en la hermana menor, quien no presentó mejoría al régimen terapéutico inicial y necesitó ampliar paraclínicos. Se observa componente alérgico a metales y se decide escalar hacia un tratamiento biológico (Dupilumab).
Conclusiones: La dermatitis atópica es una enfermedad de manifestación clínica y paraclínica heterogénea en la que convergen múltiples mecanismos fisiopatológicos intrínsecos y extrínsecos. La asociación sobre predisposición genética, herencia, microbioma y otros factores posiblemente implicados en la presentación de la dermatitis atópica entre hermanos afectados todavía no está definida, por lo que se recomienda realizar estudios que evalúen la importancia de este factor y de variables asociadas.
Guardianes del futuro
Authors: Dulcey Juan Manuel
Published: August 2023

Cuando se escoge trabajar en Pediatría, se entiende que se ha llegado a una rama a la que se dedicará toda la vida y que se va a optar por un camino a veces ingrato, en donde el sufrimiento de nuestros semejantes adquiere un significado diferente. A los pediatras nos toca ver el dolor de unos seres indefensos, pero además el de los padres y a veces el de toda una familia.
Antimicrobial activity of Bis-salicylaldehyde Ethylenediamine Schiff Base and Its Lanthanoids (III) Complexes
Authors: Mahmud, S.D.  , Birnin-Yauri,  U.A.  , Liman, M.G.  , Manga, S.B.
Published: August 2023

Schiff base readily form complex with metal ions and the resultant complexes especially from transition metals were extensively used in many fields of human endeavor including antimicrobial therapy. However, the potentials of Lanthanide-Schiff base complexes as an antimicrobial agent have not been adequately studied. This study aims to synthesize and determine the antimicrobial activity of Bis-salicylaldehyde ethylenediamine Schiff Base and its Lanthanoids (III) Complexes. The Dysprosium (III), Gadolinium (III), Neodymium (III) and Samarium (III) complexes of Schiff base derived from Salicylaldehyde and ethylenediamine were synthesized under reflux condition in ethanol and their antimicrobial activity were determined using disc diffusion method. Bis-salicylaldehyde ethylenediamine was a shiny crystalline yellow with a yield of 93% and its complexes were various sheds of yellow ranges from pale to dark, with percentage yield between 94-98%. The Bis-salicylaldehyde ethylenediamine had good activity against C. albican (32mm at 100mg/ml), A. niger (20mm at 100mg/ml) and Fusarium Spp (17mm at 100mg/ml) but its complexes had low (07-11mm at 100mg/ml) or no (06mm at 100mg/ml) activity against all the fungal isolates. The antibacterial activity of the Bis-salicylaldehyde ethylenediamine against E. coli (8mm at 100mg/ml), Pseudomonas (6mm at 100mg/ml) and Klebsiella (13mm at 100mg/ml) was lower than that of Ampiclox (between 17 to 20mm) and even though, all its Lanthanoid (III) complexes between 8 to 14mm at 100mg/ml) had higher antibacterial activity than the Bis-salicylaldehydeethylenediamine but still the activity of Lanthanoid (III) complexes was lower than that of Ampiclox. Considering the in-vitro antimicrobial activity exhibited by Bis-salicylaldehyde ethylenediamine and its Lanthanoid (III) complexes against bacterial and fungal isolates, both will not be potential antibacterial agent but Bis-salicylaldehyde ethylenediamine could be pontential antifungal agent. We therefore, recommend further researches geared toward exploring its full potentials for antifungal therapy.
Effect of Oil Pollution on the Antioxidant Activity of the Methanolic Extracts of Polluted and Unpolluted Leaves of Hyptis suaveolens (L)
Authors: Egwu, H.A.,  , Yilwa, V.M.,  , Onusiriuka, B.C.,  , Dikwa, K.B.  , Yelwa, J.M.
Published: August 2023

Hyptis suaveolens (L.) Poit, an aromatic weed known as pignut or daddoya-ta-daji in the Hausa language, has a longstanding history of usage as food and medicine in Kaduna state. This plant is interestingly found thriving in environments with or without oil pollution. In our modern industrial society, it's practically inevitable that these medicinal plants come in contact with oil contamination. This is largely because oil pipelines, often aged and susceptible to corrosion or illicit activities leading to leakages, are scattered across urban and rural settlements, influencing the plants' phytochemical composition. This study is focused on examining if oil pollution alters the antioxidant activity of this plant. An evaluation of the antioxidant properties of methanol extracts from Hyptis suaveolens (L.) leaves, both from polluted and unpolluted areas, was carried out using the 2,2-Diphenyl-1-Picrylhydrazyl-hydrate (DPPH) free radical scavenging assay. The outcomes showed that the extracts have significant (p < 0.05) concentration-dependent antioxidant activity. Yet, the unpolluted H. suaveolens leaves' methanol extract exhibited superior DPPH radical scavenging action compared to the extract from the polluted leaves. The median inhibitory concentrations (IC50) for the polluted and unpolluted leaves' methanol extracts were 35 µg/ml and 20 µg/ml respectively. Therefore, the contamination had a detrimental impact on the plant extract's antioxidant capacity.
Analisis Pengendalian Kualitas Bibit Sawit Dengan Menggunakan Metode Fault Tree Analysis (FTA) dan Metode Failutre Mode Effect Analysis (FMEA) di PT. Kapuas Sawit Sejahtera
Authors: Ridwan Wahyuniati , Widiastuti Retno , Nurhayati Emmy
Published: August 2023

Quality is an important factor related to company performance. This quality control is applied in various companies, one of which is PT. Kapuas Sawit, Sejahtera which has a problem with palm seed defects that cannot be overcome. This study aims to identify the factors causing defects in palm seed products. In addition, to provide proposed improvements that can improve the quality of palm seed products. This study uses descriptive qualitative through data analysis of the Fault Tree Analisys (FTA) method and the Failur Mode and Effect Analysis (FMEA) method. Fault Tree Analisys (FTAs). The results of the study through the FTA method obtained the factors causing dwarf defects, defects attacked by diseases, and defects attacked by pests are human, method, and environmental. Through the FMEA method, the proposed improvements made are to carry out cultivation with intensive stature, improve rest time by implementing a short rest system to reduce the impact of the workload, and provide boiler ash before and during the dry season. Researchers hope that the company will further improve the quality of oil palm seeds and that subsequent researchers can develop this research.

Keywords: Quality of Oil Palm Seeds, Fault Tree Analisys, Failure Mode and Effect Analysis
Pengaruh Pernikahan Dini terhadap Tingkat Pertumbuhan Stunting di Kelurahan Terjun Kecamatan Medan Marelan
Authors: Putri Dewi Khadijah Dinda , Hanum Khairunisa , Lubis Nadratul Hasanah , Fazrah Yasmi , Saleh Syarbaini
Published: August 2023

The purpose of this study was to determine the effect of early marriage on stunting growth rates in Kelurahan Terjun, Medan Marelan District. The research method used is an analytical observational method with a cross-sectional research design. From the results of this study, further research is still needed to overcome and prevent stunting events at the Waterfall Health Center, Medan Marelan District in order to create a stunting prevention program from its risk factors.

Keywords: Early Marriage, Growth, Stunting