bluuebunny/crossref_metadata_2025 huggingface dataset:
Dual Prognostic Classification of Triple-Negative Breast Cancer by DNA Damage Immune Response and Homologous Recombination Deficiency
Authors: Stecklein Shane R. , Barlow William , Pusztai Lajos , Timms Kirsten , Kennedy Richard , Logan Gemma E. , Seitz Rob , Badve Sunil , Gökmen-Polar Yesim , Porter Peggy , Linden Hannah , Tripathy Debu , Hortobagyi Gabriel N. , Godwin Andrew K. , Thompson Alastair , Hayes Daniel F. , Sharma Priyanka
Published: November 2023

PURPOSE

Triple-negative breast cancer (TNBC) is a heterogeneous disease. We previously showed that homologous recombination deficiency (HRD) and the DNA damage immune response (DDIR) signature are prognostic in TNBC. We hypothesized that these biomarkers reflect related but not completely interdependent biological processes, that their combined use would be prognostic, and that simultaneous assessment of the immunologic microenvironment and susceptibility to DNA damaging therapies might be able to identify subgroups with distinct therapeutic vulnerabilities.

METHODS

We analyzed the dual DDIR/HRD classification in 341 patients with TNBC treated with adjuvant anthracycline-based chemotherapy on the SWOG S9313 trial and corroborated our findings in The Cancer Genome Atlas breast cancer data set.

RESULTS

DDIR/HRD classification is highly prognostic in TNBC and identifies biologically and immunologically distinct subgroups. Immune-enriched DDIR+/HRD+ TNBCs have the most favorable prognosis, and DDIR+/HRD– and DDIR–/HRD+ TNBCs have favorable intermediate prognosis, despite the latter being immune-depleted. DDIR–/HRD– TNBCs have the worst prognosis and represent an internally heterogeneous group of immune-depleted chemoresistant tumors.

CONCLUSION

Our findings propose DDIR/HRD classification as a potentially clinically relevant approach to categorize tumors on the basis of therapeutic vulnerabilities.
A Case of Aplasia Cutis Congenita in the Setting of Maternal Carbimazole Use in the First Trimester
Authors: McGrath Colin , O’Hanrahan Nancy , Dennedy Michael Conall , Boyle Michael A
Published: November 2023

Aplasia cutis congenita (ACC) is one of several congenital malformations associated with antithyroid/thiourylene drug use in pregnancy. While uncommon among the general population (1-3/100 000 cases), the risk among those on thiourylenes is between 1.6% and 3%. The scalp is the most common site for this congenital anomaly.

We present the case of a male infant with multifocal ACC of the scalp discovered at birth and born to a mother with Graves disease that was controlled during pregnancy using carbimazole. Thyroid function tests were normal throughout the pregnancy. There was no involvement of underlying subcutaneous tissue or structures. At age 18 months, the single largest lesion remained with only partial coverage. Prospective management involved periodic surveillance with planned 2-stage repair.

This case reinforces the association between the antithyroid drugs carbimazole (CMZ) and methimazole (MMI) and supports the proposition of an MMI/CMZ embryopathy. It adds to a literature of case reports in which malformations arise in offspring of such mothers whose thyrotoxicosis is controlled antenatally, thereby challenging the suggestion that ACC is attributable to poorly controlled disease rather than thiourylenes. As yet the underlying mechanism is not understood, nor is it known why MMI and CMZ may cause potentially significant embryopathy while congenital defects attributable to the structurally similar propylthiouracil are typically less severe.
Measuring body temperature in birds – the effects of sensor type and placement on estimated temperature and metabolic rate
Authors: Andreasson Fredrik , Rostedt Elin , Nord Andreas
Published: November 2023

Several methods are routinely used to measure avian body temperature, but different methods vary in invasiveness. This may cause stress-induced increases in temperature and/or metabolic rate and, hence, overestimation of both parameters. Choosing an adequate temperature measurement method is therefore key to accurately characterizing an animal's thermal and metabolic phenotype. Using great tits (Parus major) and four common methods with different levels of invasiveness (intraperitoneal, cloacal, subcutaneous, cutaneous), we evaluated the preciseness of body temperature measurements and effects on resting metabolic rate (RMR) over a 40°C range of ambient temperatures. None of the methods caused overestimation or underestimation of RMR compared with un-instrumented birds, and body or skin temperature estimates did not differ between methods in thermoneutrality. However, skin temperature was lower compared with all other methods below thermoneutrality. These results provide empirical guidance for future research that aims to measure body temperature and metabolic rate in small bird models.
Παιδικό παιχνίδι και δημόσιος χώρος
Authors: Παπασωτήρη Γαρυφαλιά
Published: November 2023

H παρούσα επιστημονική εργασία έχει ως αντικείμενο τη διερεύνηση ερωτημάτων γύρω από τη σχέση που αναπτύσσουν τα σύγχρονα παιδιά με το φυσικό και τον ψηφιακό χώρο κατά τη διάρκεια του παιχνιδιού, μέσα από την εθνογραφική μελέτη δύο ομάδων παιδιών ηλικίας 7-14 ετών που έπαιζαν σε δημόσιους χώρους της πόλης του Αγρινίου το 2016-2017. Η διατριβή χωρίζεται σε δύο μέρη. Στο πρώτο μέρος, το οποίο αποτελείται από δύο κεφάλαια, παρουσιάζονται τα ερευνητικά ερωτήματα της διατριβής και αναλύονται οι βασικές θεωρητικές αφετηρίες της εργασίας με άξονα τις θέσεις της Νέας Κοινωνιολογίας της παιδικής ηλικίας και τις σύγχρονες θεωρίες του υλικού πολιτισμού. Στην εισαγωγή γίνεται συζήτηση των ορισμών βασικών εννοιών της διατριβής και αναλύονται οι στόχοι της. Στο πρώτο κεφάλαιο γίνεται ανασκόπηση των διεθνών και ελληνικών ερευνών με αντικείμενο την παιδική ηλικία και το παιχνίδι, καθώς και τη σχέση του παιδικού παιχνιδιού με το δημόσιο χώρο και ειδικότερα με: το χώρο της γειτονιάς, το σχολικό προαύλιο και το χώρο της παιδικής χαράς. Το δεύτερο μέρος της διατριβής (κεφάλαια 2-7) πραγματεύεται την αναλυτική παρουσίαση της έρευνας και των ευρημάτων της. Το δεύτερο κεφάλαιο ασχολείται με θεωρητικά και μεθοδολογικά ζητήματα σχετικά με την προσέγγιση της παιδικής ηλικίας, του παιχνιδιού και της σχέσης των παιδιών με το χώρο στην ύπαιθρο και στις πόλεις. Επιπλέον θίγονται ζητήματα ηθικής δεοντολογίας στη μελέτη παιδιών, και παρουσιάζεται η μέθοδος της παρούσας έρευνας, η οποία πραγματοποιήθηκε με συμμετοχική παρατήρηση διάρκειας 15 μηνών σε τρεις υπαίθριους χώρους της πόλης. Στο τρίτο κεφάλαιο παρουσιάζονται αναλυτικά οι τρεις χώροι της έρευνας όπου δραστηριοποιούνταν οι δύο ομάδες παιδιών του δείγματος παρατήρησης, ο χώρος του προαύλιου ενός δημοτικού σχολείου που χρησιμοποιείται τις απογευματινές ώρες ως χώρος ελεύθερου παιχνιδιού και άθλησης, ο χώρος μίας παιδικής χαράς και ο χώρος της πιλοτής μίας πολυκατοικίας στο κέντρο της πόλης. Το τέταρτο κεφάλαιο αναλύει τις σχέσεις των παιδιών με τους ενήλικους και με τους συνομήλικους, με έμφαση στις έμφυλες διαστάσεις του παιχνιδιού και της χρήσης του χώρου. Το πέμπτο κεφάλαιο συζητά τη σχέση των παιδιών που συμμετείχαν στην έρευνα με το χώρο και τα υλικά του παιχνιδιού και αναλύεται η επίδραση των προσφερόμενων δυνατοτήτων των στοιχείων του χώρου και των ποικίλων υλικών του παιχνιδιού -φυσικών ή εμπορικών- στο συμβολικό και στο κινητικό παιχνίδι των παιδιών. Το έκτο κεφάλαιο ασχολείται με ερωτήματα σχετικά με την επίδραση των νέων τεχνολογιών στο σύγχρονο παιδικό παιχνίδι με αφορμή την παρατήρηση του υβριδικών μορφών παιχνιδιού των παιδιών του δείγματος. Το έβδομο και τελευταίο κεφάλαιο παρουσιάζει τα συμπεράσματα της έρευνας και συζητά τους περιορισμούς της προτείνοντας ερωτήματα για μελλοντικές έρευνες.
Η κοινοβουλευτική μειοψηφία
Authors: Μακροπούλου Γεωργία
Published: November 2023

Η παρούσα διατριβή φιλοδοξεί να εμβαθύνει στη λειτουργία της σχέσης πλειοψηφίας και μειοψηφίας στο ελληνικό Κοινοβούλιο σε μία συνολική συγκριτική θεώρηση, κατά την οποία εξετάζονται θεσμική κατοχύρωση, ιστορική διαδρομή, δυναμική και προοπτικές της κοινοβουλευτικής μειοψηφίας. Αναζητά τη θέση της κοινοβουλευτικής μειοψηφίας στο συνταγματικό σύστημα ισορροπίας της σχέσης της με την κοινοβουλευτική πλειοψηφία και τον βαθμό προστασίας των δικαιωμάτων της κατά το σχετικό ρυθμιστικό πλαίσιο και την ακολουθούμενη κοινοβουλευτική πρακτική. Η έρευνα στο πρώτο μέρος της εκκινεί από την ιστορική και τη δογματική θεμελίωση εγγυήσεων προστασίας της κοινοβουλευτικής μειοψηφίας, συμπεριλαμβανομένης της κοινοβουλευτικής αντιπολίτευσης. Εν συνεχεία, στο δεύτερο μέρος, εξετάζεται η σταδιακή εξέλιξη της νομικής αποτύπωσης των εν λόγω εγγυήσεων στο Ηνωμένο Βασίλειο, τη Γαλλία, τη Γερμανία και τη χώρα μας, μαζί με τη σχετική θεωρητική προσέγγιση. Το εν λόγω συγκριτικό πλαίσιο αναλύεται, περαιτέρω, με αρκετά τεχνικό χαρακτήρα στο τρίτο μέρος της έρευνας, ως προς τον σύγχρονο θεσμικό σχεδιασμό και τη λειτουργία των κοινοβουλευτικών μηχανισμών του, προκειμένου να τεκμηριωθεί ο τρόπος διάπλασης και τα λειτουργικά χαρακτηριστικά της σχέσης κοινοβουλευτικής πλειοψηφίας και κοινοβουλευτικής μειοψηφίας σήμερα. Το τελευταίο τμήμα της διατριβής αποτιμά, υπό το φως των ανωτέρω, τον συσχετισμό της εξουσίας εντός του Κοινοβουλίου, το καθεστώς των μειοψηφούντων κομμάτων και προτάσεις ενίσχυσης της θέσης της κοινοβουλευτικής μειοψηφίας προς την κατεύθυνση της ουσιαστικότερης και δημοκρατικότερης λειτουργίας του Κοινοβουλίου, συμβάλλοντας, μαζί με το σύνολο των επιμέρους αναπτύξεων, στη μελέτη της θεσμικής εξέλιξης στο ελληνικό Κοινοβούλιο και προσφέροντας μία βάση για περαιτέρω έρευνα.
Using responsive feedback from routine monitoring data to guide course corrections for a family planning intervention in Nigeria
Authors: Meekers Dominique , Olutola Olaniyi , Abu Turk Lynn
Published: November 2023

Background This paper aims to promote the use of simple interrupted time series (ITS) analyses of routine data as a responsive feedback tool to improve public health programs. Although advanced ITS techniques exist, their use is often not feasible due to limitations in funding or research capacity. We propose an Excel-based analysis that requires minimal resources or statistical expertise, and illustrate it by measuring the effect of a radio campaign to promote a family planning call center in Nigeria on the demand for family planning information. Methods We used a single group interrupted time series design (ITS) as a responsive feedback mechanism to determine whether the radio campaign influenced use of the Honey&Banana call center. ITS is ideal when there is no control group. ITS uses the pre-intervention trend to predict what would have happened if the intervention were absent. Results After conducting ITS analyses, the results show that the number of calls requesting family planning information increased throughout the campaign period, with a gain of about 500 additional calls per month, and then decreased after the campaign ended. However, the number of calls gained from the campaign was substantially lower than anticipated. Conclusions While end-of-project impact evaluations are necessary, there should be regular feedback system to provide program implementers with information about the status of the project, such as failures, successes, and areas of improvements. This would allow implementers to make necessary adjustments as needed throughout the intervention period. The finding that the radio campaign was not living up to expectations helped Honey&Banana program implementers to end the campaign prematurely and re-allocate resources to a more promising activity. Our research shows that basic Excel-based ITS analysis of routine data can be a useful tool for receiving regular feedback to guide programming improvements for organizations that have limited resources and/or research capacity.
Symboliczne wymiary tajwańskiego nacjonalizmu
Authors: Zemanek Bogdan
Published: November 2023

THE SYMBOLIC DIMENSION OF TAIWANESE NATIONALISMA great majority of Taiwanese people declare themselves to be Taiwanese only (61% in 2022) or Taiwanese and also Chinese (additional 31%), which gives an impression of ethnic and national unity. However, the divisive factors of (sub) ethnic grouping, language diversity and historical consciousness are still present. Taiwanese nationalism, which in its civilian form is organized around present state of Republic of China (ROC) as opposed to the People’s Republic of China (PRC). However, ROC, although de facto an independent state is not de iure a Taiwanese state, as can be seen in its national symbolism. The paper analyses this enthosymbolical dimension of Taiwanese national identity, discussing four main symbolical spheres: the memory of the 2-28 Incident; memory and idealization of the Japanese colonial period; strong presence of local languages, used alongside the official northern mandarin standard; and finally, the presence of the Aborigine people and their cultures. All these spheres are important in Taiwan symbolical space, and their importance is further strengthened by the actions of the state (public commemorations, protecting the cultural relicts of Japanese period, removing the ones connected with authoritarian regime of Chiang Kai shek etc.). However, the author remains doubtful if they have enough emotional and symbolical power to unite Taiwanese in the face of the Chinese threat. Closely related question is the future effect of the recommendations of the report of the Commision of Transitional Justice about the monuments of the KMT period, whose fate is a strongly contested issue, and which needs further research.
Czynnik tajwańsko-chiński w strategii i polityce Francji wobec Indo-Pacyfiku
Authors: Młynarski Tomasz
Published: November 2023

THE TAIWANESE-CHINESE FACTOR IN FRANCE’S STRATEGY AND POLICY TOWARDS THE INDO-PACIFIC
The aim of this article is to provide a synthetic overview of France’s involvement into the Indo-Pacific region, in the context of the protection of important national interests related to the possession of overseas territories. This article analyses impact of the French-Chinese bilateral cooperation on relations with Taiwan. The author points out that France has recognized the government of the PRC as the only representative of China since 1964 and does not maintain diplomatic relations with Taiwan, emphasizing that this is a permanent position, initiated by General de Gaulle, and cooperation between Paris and Taipei is developed in accordance with the “one China policy.” The second aspect of the analysis of France’s policy and strategy towards the Indo-Pacific region was embedded in the broader framework of political, economic relations and military alliances with Asian countries as an element of promoting a multipolar order and stopping Chinese expansionism in the Indo-Pacific area and strengthening its own geopolitical position against the background of China’s rivalry with United States.
Dialogando sobre direitos sexuais com os usuários do SUS nos espaços de atendimento da Policlínica Piquet Carneiro – PPC/UERJ
Authors: Silva Welison Matheus Fontes da
Published: November 2023

Os direitos sexuais, embora sejam reconhecidos em documentos nacionais e internacionais, enfrentam, ainda hoje, muitos desafios para que sejam, de fato, garantidos. Considerando que essa temática adentra por diversas áreas da nossa vida, como a saúde, a educação, a cidadania, dentre outros, torna-se relevante promover discussões sobre direitos sexuais para que estes sejam conhecidos e reconhecidos também como direitos básicos de todo ser humano. Este artigo tem como objetivo apresentar as atividades de grupos de sala de espera desenvolvidas pelo projeto de extensão “Repensando as estratégias para a prevenção e a promoção da saúde em ISTs e HIV/AIDS” realizadas nos ambulatórios da Policlínica Piquet Carneiro. Descreve os encontros com os usuários do SUS, a partir dos relatos compartilhados através da dinâmica adotada na execução dos grupos de sala de espera. As atividades ocorreram entre maio e setembro de 2019 e tiveram o alcance de 234 participantes. Os participantes são receptivos, demonstram boa aceitação e interesse durante a realização das dinâmicas e participam das atividades propostas pelos integrantes da equipe. Nossa proposta é esclarecer aos usuários, através das práticas pedagógicas, sobre os direitos sexuais, estimulando a reflexão de um modo que fosse possível relacionar esse debate a temas macropolíticos e questões analíticas enfrentadas cotidianamente, tais como o machismo, prevenção das ISTs, direitos das mulheres e da população LGBT, abuso sexual infantil, educação sexual dentro de um contexto escolar, outros. Acreditamos que o diálogo e ações de conscientização podem favorecer a mudança de atitude e contribuir para a garantia dos direitos sexuais.
Projeto Razão Social: Projeto de Responsabilidade socioambiental e de Desenvolvimento Regional
Authors: Camargo LUIS HENRIQUE
Published: November 2023

Este texto traz o debate em torno do projeto Razão Social da UERJ. Trata-se de um modelo de gestão territorial-ambiental. O mesmo pretende criar uma rede de empreendedores ambientais a partir da potencialidade espacial de comunidades carentes do Estado do Rio de Janeiro. Para consolidar esses objetivos, o mesmo é dividido em quatro fases: levantamentos iniciais, pesquisa de campo, curso de formação de empreendedores e a geração de uma rede de negócios ecológicos. O monitoramento seguirá a lógica do desenvolvimento constante de totalizações no espaço, fruto de relações não lineares, sendo assim aplicará métodos ligados ao campo da auto-organização e da complexidade associados à leitura miltonsantaniana da realidade. Um dos principais objetivos específicos é a partir do debate com a comunidade alterar as formas-conteúdo buscando soluções sustentáveis.
Estudo de Público da Exposição Circuito Plantas Exóticas da Vila Dois Rios em Ilha Grande – Angra dos Reis, Rio de Janeiro - Brasil
Authors: Moreira Nattacha dos Santos , Costa Warlen Silva da , Rosa Paulo Ricardo Artulano , Pierre Raphaella Moreira , Tirado Matheus da Silva , Castilhori Marcelo Fraga , Reis Ricardo Carneiro da Cunha , Manão Carla YGubáu , Callado Cátia Henriques
Published: November 2023

A exposição Circuito Plantas Exóticas da Vila Dois Rios é uma iniciativa do Parque Botânico do Ecomuseu Ilha Grande. Representa uma experiência inovadora, que socializa informações e incentiva à reflexão crítica sobre os impactos de plantas exóticas na biodiversidade, atuando como subsídio à conservação dos ecossistemas da Ilha Grande. Conhecer o perfil do público visitante permite adequar a comunicação entre exposição e visitante e assim atingir efetivamente a sua proposta educativa. Sendo assim, este trabalho teve por objetivos identificar nos visitantes: (1) o perfil sociodemográfico; (2) o conhecimento quanto à área e a motivação para visitá-la; (3) o conhecimento quanto às plantas exóticas e seus impactos e (4) o conhecimento sobre a própria exposição. Os resultados indicam que a maioria dos visitantes foi adulta, entre 24 e 49 anos, sem predomínio de gênero e majoritariamente brasileiros (89%). Os visitantes apresentaram considerável conhecimento sobre a localidade. Entretanto, desconheciam a gestão da Universidade do Estado do Rio de Janeiro (UERJ) no local. Além disso, o estudo confirmou o desconhecimento do público sobre as espécies exóticas e o impacto destas sobre os ecossistemas naturais. Cabe ressaltar que os resultados obtidos neste trabalho reforçam o potencial educativo do Circuito acerca da temática plantas exóticas e seus impactos na Ilha Grande e destacam a necessidade de aumentar a divulgação da exposição.
Ações educativas em local de vulnerabilidade social: um novo caminho à promoção da saúde
Authors: Bezerra Luciana Brandão , Filomeno Carlos Eduardo da Silva , De Melo Thainá , Lima Ludmila Rocha , Bernardo Joana , Da Silva Bruno Moraes , Bruno Isadora do Monte Silveira , Ramalho Ivaneide de Almeida , Leal Claudia Moraes Clemente , Gomes Regina Bontorim , Machado Beatriz Albuquerque , Radighieri Adriana Raineri , Teixeira Taynara Vieira , Da Rosa Aline Aparecida , Brito Andréia Carolinne de Souza , Leite Karine Gomes , Neves Renata Heisler
Published: November 2023

No Brasil, a pobreza urbana é expressa nas favelas, que encontram inúmeros desafios, devido as desigualdades e vulnerabilidade social decorrentes de diversas falhas de políticas públicas, como em educação e saúde. A participação de projetos sociais nas comunidades permite a integração da população e a colaboração na construção de pensamentos críticos que contribuem para a transformação social. O estudo foi realizado com estudantes da educação básica e seus responsáveis, moradores da favela Morro dos Macacos, RJ. Tendo como objetivo a promoção à saúde, integrantes dos projetos Parasito EDUCAC e LiPar realizaram uma ação educativa e interativa em uma Creche Municipal. As ações incluíram metodologias plurais para a promoção à saúde, aplicação de um questionário e palestra. As apresentações das diversas atividades foram bem aceitas, despertando o interesse investigativo nos alunos, trazendo reflexão acerca de medidas para o controle e prevenção de doenças parasitárias através de uma linguagem simples e apropriada à faixa etária. Houve a participação ativa dos responsáveis, tornando possível verificar o domínio de informações, permitindo o esclarecimento de dúvidas e transmissão de informações pertinentes acerca de questões de higiene, saúde básica e parasitoses. As abordagens de Educação em saúde possibilitaram expansões na aprendizagem com crianças e responsáveis, apresentando conceitos, medidas e, principalmente, analisando com os pais os fatores que levam a população à situação de doenças.
Uso de redes sociais como ferramenta de conscientização contra o tabagismo
Authors: Oliveira Braga Lucas , Gregório de Góes Vanessa , Bispo do Carmo Beatriz , Garcia de Andrade Maíra , De Oliveira Otero Geovana D’Arc , Farias da Silva Jaonayly , Borja Gómez Luis Fernando
Published: November 2023

O fumo está associado a diversas comorbidades, compondo um dos fatores de risco mais importantes para as doenças crônicas não transmissíveis. Além de pré-dispor um vasto leque de doenças, o tabagismo causa impacto socioambiental e socioeconômico. Nesse contexto, a Liga Acadêmica de Pneumologia e Cirurgia Torácica do Acre (LAPCITO-AC) organizou e promoveu ações de impacto, cujo objetivo foi alinhar-se às intervenções realizadas pelo Ministério da Saúde em busca da prevenção e cessação do fumo.  Tais ações foram contempladas virtualmente por meio de aulas, seminários e publicações nas redes sociais e plataformas da LAPCITO-AC. Por fim, notou-se que a utilização dessas mídias sociais possibilitaram uma abrangência satisfatória da população, chegando a 3.133 alcances durante as 14 publicações do projeto. Com isso, ficou evidente a importância do uso das redes sociais como veiculadora de informações para a continuação das atividades de extensão em período de distanciamento social.
Pandemia de "fake news" sobre plantas medicinais no combate à COVID-19
Authors: Oliveira Anne Sgambato de , Venancio Nayara de Almeida Rodrigues , Hoffmann André , Joffily Ana , Anholeti Maria Carolina , Paiva Selma Ribeiro de
Published: November 2023

Desde o fim de 2019, a pandemia causada pelo novo coronavírus (SARS-CoV-2) tem afetado o mundo. A partir de então, informações equivocadas se espalham diariamente por diferentes mídias. Isso tem sido recorrente em relação ao uso de plantas medicinais para o tratamento da doença (COVID-19), as quais, quando usadas de forma indiscriminada, podem até agravar a condição do paciente. Nesse sentido, é importante a divulgação de informações úteis e confiáveis para a sociedade. Este trabalho relata o desenvolvimento de um projeto que objetiva divulgar conhecimentos científicos sobre a utilização de plantas medicinais, especialmente as supostamente relacionadas ao tratamento da COVID-19. Conteúdos informativos, no formato de vídeo e imagem, foram produzidos e disponibilizados através das plataformas do Youtube, Instagram e Facebook. Os vídeos publicados no Youtube contendo as plantas medicinais Allium sativum, Colocasia esculenta e Dioscorea spp. foram responsáveis pelo maior número de visualizações e impressões possivelmente devido à grande repercussão das “fake news” envolvendo receitas caseiras com essas plantas. Dessa forma, o projeto contribuiu para orientação da população e para o uso seguro de plantas medicinais.
Educação remota em saúde para indivíduos idosos e outras populações vulneráveis à COVID-19
Authors: Gonze Bárbara de Barros , Volpe Márcia Souza , Capellini Verena Kise
Published: November 2023

Trata-se de um relato de experiência, proporcionado por um projeto de extensão, que objetivou promover saúde, prevenir doenças e agravos e reduzir riscos decorrentes da pandemia de coronavírus e da inatividade física, secundária ao isolamento social, em indivíduos vulneráveis, especialmente os idosos. De agosto de 2020 a janeiro de 2021, nove graduandos em Fisioterapia, sob tutoria de seis docentes, participaram de seis ciclos, criando 22 produtos educativos (06 cartilhas, 05 posts, 06 vídeos e 05 podcasts) sobre os seguintes temas: prevenção de quedas, proteção articular, fragilidade, imunidade, demência e tabagismo. Em todas essas temáticas, o papel dos exercícios físicos e orientações sobre distanciamento social, uso de máscaras e higienização das mãos foram enfatizados. A divulgação dos produtos educativos foi realizada via e-mail, mídias sociais (WhatsApp, Instagram, Facebook e YouTube) e canais oficiais da Universidade. Até 05/04/2021, os produtos educativos alcançaram 739 idosos, em Instituições de Longa Permanência, e 6.591 pessoas, via redes sociais. Este projeto alcançou um grande número de pessoas, propiciando educação em saúde em tempos de isolamento social. Sua abrangência superou as expectativas de faixa etária do público-alvo, contudo, acredita-se que a acessibilidade de idosos à tecnologia tenha sido o principal desafio para a consolidação da educação remota nessa população. O projeto possibilitou, aos estudantes, atuação em saúde, durante o período de distanciamento social, e aquisição de saberes essenciais para a formação.
TERRITORIALIDADE, JURISDIÇÃO E INTERNET: ALGUNS ASPECTOS DE DIREITO INTERNACIONAL PRIVADO
Authors: Tiburcio Carmen , Albuquerque Felipe
Published: November 2023

O presente artigo examina a interrelação entre as concepções espaciais subjacentes ao direito internacional privado e à internet. Para isso, apresenta-se um panorama das regras de fixação da jurisdição no direito internacional privado para, em seguida, examinar decisões de tribunais brasileiros, norte-americanos e europeus examinando a delimitação da competência internacional em casos envolvendo a internet. O objetivo do trabalho é examinar como algumas premissas tradicionais do direito internacional privado foram afetadas pela superveniência da internet e, ao contrário, como a regulação afetou o desenvolvimento da internet. O artigo sustenta que o uso intensivo de critérios como acessibilidade e dano demonstra a resiliência do conceito de territorialidade no direito internacional privado e está na origem de algumas ferramentas amplamente utilizadas atualmente, como mecanismos de geolocalização, redes privadas virtuais (VPNs) e restrições geográficas em contratos de distribuição. Não obstante representarem, fundamentalmente, um conflito entre concepções espaciais abstratas, essas visões divergentes apresentam repercussões concretas relevantes. O artigo examina como os sistemas de fixação de jurisdição no direito internacional privado responderam aos desafios postos pelo crescente número de litígios envolvendo ilícitos praticados pela internet e, sob outra perspectiva, como a concepção de jurisdição produziu efeitos sobre a concepção original da internet.   Embora não seja o único exemplo, o caso tipicamente discutido pela doutrina envolve a publicação online de conteúdo reputado ofensivo por indivíduo ou empresa cujo domicílio ou sede se encontra em local diverso daquele onde se encontra a sede da empresa responsável pela publicação do conteúdo. De modo a examinar o tema, o presente artigo (i) apresenta as regras tradicionais de fixação no direito internacional privado; e (ii) examina as soluções encontradas por tribunais brasileiros, norte-americanos e europeus para a fixação de jurisdição em litígios civis envolvendo a internet. Como se demonstrará, se a internet foi inicialmente concebida como um espaço sem fronteiras, exigências econômicas e políticas, mas também jurídicas, estão na origem de um número cada vez maior de restrições (territoriais) à livre circulação de dados na internet. Para elaboração do artigo, adotou-se como metodologia a revisão bibliográfica, incluindo literatura jurídica nacional e estrangeira, e a pesquisa jurisprudencial concentrada nas decisões proferidas pelo Superior Tribunal de Justiça (STJ).
APLICAÇÃO DAS MEDIDAS EXECUTIVAS ATÍPICAS (ARTIGO 139, IV, DO CPC/15): CONSIDERAÇÕES SOBRE A QUEBRA DE SIGILO BANCÁRIO E A PENHORA DE FATURAMENTO
Authors: Marques de Medeiros Neto Elias , Marra Moreira Rodrigues de Oliveira Caio
Published: November 2023

O artigo aborda a aplicação das medidas executivas atípicas autorizadas pelo art. 139, IV, do Código de Processo Civil do Brasil, de 2015 (“CPC/15”), sob um enfoque prioritário e não apenas subsidiário para garantir maior efetividade ao processo executivo, com ênfase na aplicação da quebra de sigilo bancário e da penhora de faturamento. Para tanto, em um primeiro momento, parte-se de uma análise acerca do atual posicionamento predominante dos Tribunais pátrios sobre o uso de medidas executivas, que se lastreia, em grande medida, na priorização da aplicação das medidas típicas na execução. Em um segundo momento, reflete-se sobre a necessidade de adoção de uma nova prática judicial diante de hipóteses em que a aplicação das medidas executivas típicas se revela insuficiente para garantir ao credor o direito perseguido, demonstrando-se, então, a necessidade de utilização das medidas autorizadas pelo art. 139 do CPC/15. Nesse contexto, examina-se que se, por um lado, a atipicidade executiva tem por finalidade a eficiência, a utilidade e a adequação, consagrando os princípios constitucionais da eficiência processual, da duração razoável do processo e do acesso à justiça, por outro lado, é também na Constituição de 1988 que se encontram as balizas à aplicação das medidas executivas atípicas. Assim, abordando-se as polêmicas jurisprudenciais e doutrinárias que circundam a adoção dos poderes autorizados pelo art. 139, IV, do CPC/15, em especial o recente julgamento da ADI 5.941 pelo STF, reflete-se sobre como as medidas atípicas podem ser mais adequadamente utilizadas, guiadas pela busca da satisfação do direito do credor, mas sem ultrapassar a esfera patrimonial do devedor. Ao final, com especial enfoque sobre a quebra de sigilo bancário e a penhora de faturamento, propõe-se a aplicação prioritária dessas medidas executivas atípicas, e não apenas subsidiária, mediante a análise de sua pertinência, necessidade e proporcionalidade no caso concreto, sempre respeitados os direitos fundamentais do devedor.
ITALY 2023, RIFORMA CARTABIA INNOVATIONS IN THE CIVIL PROCESS AND ADR; POTENTIAL INTERAC-TIONS?
Authors: Matteucci Giovanni
Published: November 2023

Civil cases pending in Italian civil courts at the end of 2019 no. 5,826,440. Delegated Law 69/2009 and Legislative Decree 28/2010 ruled mandatory civil commercial mediation in the contemporary Italian legal system. Strong opposition from lawyers and benign neglect from the judiciary. Main objection: “Mediation does not belong to the Italian legal culture”: History teaches the opposite! 2012, the intervention of the Constitutional Court, excess of delegation; back to voluntary mediation. Law decree 69/2013, called “Del fare”, ruled the OPT-OUT mandatory mediation procedure, the compulsory lawyer’s assistance and declared lawyers mediators “ope legis”! 2017, Alpa Commission (“A world of experience has opened up, that … until now had not been perceived in all its extent and complexity”); the final report remained in a drawer. Delegated Law 206/2011, Luiso Commission (“The process will be civil”), Legislative Decree 149/2022, Riforma Cartabia: major innovations in the code of civil procedure and ADR. The new cognitive process under ordinary procedure is based on the anticipation of the first hearing: documents by the parties already laid out, so that the judge, after the free and non-formal questioning of the parties, can proceed to assess the admissibility and relevance of the means of proof and set the trial-calendar. June 30, 2023, mediation 4.0 takes off: increase of compulsory subjects; enhancement of the court-mandated mediation, involvement of the public administration, regulation of the report of the technical consultant in mediation, ODR, opposition to injunctions, tax incentives and fines to achieve the effectiveness of the procedure. As of October 10, 2023, the standards for fees of procedures and quality of training are still pending. Will the requirements for the parties' lawyers to prepare all the necessary documentation immediately before the first hearing (and the associated expensive fees for their clients) induce the parties to consider going to mediation more in order to avoid litigation (and its costs)?
I NUOVI CRITERI DI REDAZIONE DEL RICORSO PER CASSAZIONE DOPO LA RIFORMA CARTABIA
Authors: Licci Paola
Published: November 2023

Il contributo esamina la nuova disciplina del ricorso per cassazione in Italia, alla luce della riforma Cartabia sul processo civile. La nuova disciplina impone che il ricorso si adegui ai nuovi principi in materia di redazione degli atti che dovranno essere sintetici e chiari. Si vedrà in che modo tale previsione inciderà in concreto nei modi di proposizione del ricorso.
Journal scan
Authors: Welyczko Nikki
Published: November 2023

A brief overview of recently published articles on gastroenterology, hepatology and stoma care
The RCN Congress: what it can do for your practice
Authors: Ball Alison
Published: November 2023

Alison Ball gives a roundup of the RCN 2023 Congress and looks ahead to their 2024 plans
An introduction to rectal balloon expulsion tests in a pelvic floor clinic
Authors: Kumar Shaila
Published: November 2023

Biofeedback is a non-surgical treatment option for patients with pelvic floor symptoms, including faecal, flatus, urinary incontinence, obstructed defecation and evacuatory difficulties. A biofeedback therapist assesses the patient's pelvic floor muscle coordination and monitors their response to an inflated balloon acting as a simulated stool. Most patients attending the biofeedback clinic exhibit anorectal discoordination, which can be effectively corrected with rectal balloon expulsion exercise. Biofeedback therapy for pelvic floor dysynergic symptoms consists of biofeedback technique-guided pelvic floor relaxation, improving abdominal push effort, followed by simulated defecation and sensory training. This article discusses how to perform a rectal balloon expulsion test in a clinical setting by a trained therapist to improve clinical outcomes for pelvic floor dysfunction symptoms.
Assessing the impact of chlorella phenolic-rich extract on gastrointestinal health and function
Authors: Gharehbeglou Pouria , Homayouni-Rad Aziz , Sarabandi Khashayar , Akbarbaglu Zahra , Jafari Seid Mahdi
Published: November 2023

Chlorella phenolic-rich extract has been studied due to its potential therapeutic effects on the gastrointestinal tract. In vivo and in vitro studies have demonstrated that consumption of Chlorella phenolic-rich extract can modulate gut microbiota, reducing inflammation and oxidative stress. Several studies have shown that Chlorella supplementation may improve symptoms of gastrointestinal diseases, such as ulcerative colitis and irritable bowel syndrome, as well as reducing liver enzyme levels in patients with metabolic dysfunction-associated steatotic liver disease and H. pylori infection rates in children. However, further research should be conducted to fully understand the mechanisms of action and potential therapeutic benefits of Chlorella phenolic-rich extract in the gastrointestinal tract. Patients should consult with experts before taking Chlorella, so that they can be made aware of the potential side effects and any relevant mediation interactions. Overall, the use of Chlorella phenolic-rich extract is an innovative subject where there is a need for researchers to examine the potential treatment of various gastrointestinal conditions. Additional researchers are needed to fully evaluate its effectiveness and safety.
Applying organisational behaviour theory to aid emergency staff retention
Authors: Montminy Nathaniel , Russell Eric J , Holley Steve
Published: November 2023

The purpose of this theoretical concept article is to spark a dialogue on the use of organisational behaviour theory to address emergency responder retention. In the United States, emergency medical services (EMS) appear to be burdened with continuing problems of retaining staff. Poor responder retention affects the ability of EMS to deliver high-quality services; without trained, educated and experienced first responders, the EMS system struggles, and what suffers is the ability to provide medical care. The authors set out to construct a pathway for addressing the underlying issues leading to the exodus of professionals using organisational behaviour theory. To develop the idea, an inductive logic approach was used to address underlying negative factors influencing poor retention and discuss the promise of organisational behaviour theory in improving the retention of responders.
Performance of Solar-based Electrochemical System as Post-treatment of Hospital Wastewater Contaminated with Ciprofloxacin
Authors:   Department of Civil Engineering, Thammasat School of Engineering (TSE), Thammasat University, Pathum Thani 12120, Thailand, Suanjan Kritchanon , Liamlaem Warunsak ,   Department of Civil Engineering, Thammasat School of Engineering (TSE), Thammasat University, Pathum Thani 12120, Thailand, Hamjinda Nutta Sangnarin ,   Department of Environmental Science, Faculty of Science and Technology, Thammasat University, Pathum Thani 12120, Thailand, Polprasert Chongrak ,   Department of Civil Engineering, Thammasat School of Engineering (TSE), Thammasat University, Pathum Thani 12120, Thailand
Published: November 2023

T his research evaluated performance of a solar-based electrochemical system as a post-treatment of hospital wastewater contaminated with Ciprofloxacin (CIP), an antibiotic drug. Two laboratory-scale electrochemical units, and consisting of 2-5 anode and 1-4 cathode plates, were employed. Two types of electrode plates, aluminum (Al) and stainless steel (Ss), were installed in the units and their treatment efficiencies were investigated. Optimum conditions of the electrochemical system were determined by using a synthetic wastewater containing 0.01-20 mg/L of CIP (batch system); these experimental results were validated by using an actual hospital wastewater and a solar-based electrochemical system (continuous system). The experimental results of the batch system showed that the maximum CIP removal of 69% could be achieved at 10 minutes of hydraulic retention time (HRT), 18 volts in a voltage of power source (VPS), 83 A/m2 of current density (CD), and 1 cm of inter-electrode distance (IED) on Al plates. Similar results in the continuous system were obtained when the electrochemical system was fed with hospital wastewater containing CIP of about 350 ng/L. Application of solar-based energy in the electrochemical system showed similar efficiency of CIP removal, suggesting the applicability of the clean energy system for post-treatment of hospital wastewater containing antibiotic drugs
The Effect of Double Solution Treatment on Changes in the Microstructure of Austenitic Manganese Steel
Authors:   Department of Physics, Faculty of Science and Technology, Syarif Hidayatullah State Islamic University Jakarta, Ir. H. Juanda Street, No. 95, Ciputat, South Tangerang, Ban-ten,15412, Indonesia, Tjahjono Arif , Frendyta Nadya Salsabila ,   Department of Physics, Faculty of Science and Technology, Syarif Hidayatullah State Islamic University Jakarta, Ir. H. Juanda Street, No. 95, Ciputat, South Tangerang, Ban-ten,15412, Indonesia, Paristiawan Permana Andi ,   Research Center for Metallurgy, National Research and Innovation Agency (BRIN), Raya Serpong Street, Building 470, KST BJ Habibie Area, South Tangerang, Banten, 15314, Indonesia
Published: November 2023

R esearch has been carried out to eliminate of the carbide phase (FeMn)3C at the grain boundaries through a double solution treatment. The process begins, which is heating the steel to a temperature of 1000°C with a holding time of 100 minutes, then hot rolling is carried out by 28%. Furthermore, the steel reheated from room temperature to 1100°C with a holding time of 20 minutes, followed by a double solution treatment process, which is heating the steel gradually from room temperature to 730°C with a holding time of 30 minutes, then heating is continued to a temperature of 1000°C with a holding time of 15 minutes, and quenching by water. SEM mapping shows steel contains Fe, Mn, C, S, Si and Ni elements. XRD characterization showed that the double solution treatment process did not change the constituent phases in the form of Fe3O4, γ-Mn, γ-Fe, α-Fe and MnO2, but reduce the crystalline size from 0.0247 to 0.0223 μm. Based on optical microscope and SEM observations, it can be seen that the double solution treatment process was also able to reduce the grain size from 5.33 to 1.30 μm and remove the carbide (FeMn)3C phase at the grain boundaries, as well as successfully change the morphology from cleavage areas to dimple areas.
https://epg.science.cmu.ac.th/ejournal/journal-detail.php?id=11761
Authors:   Center for Yunnan Plateau Biological Resources Protection and Utilization, College of Biological Resource and Food Engineering, Qujing Normal University, Yunnan 655011, P.R. China, Lu Wen-Hua , Tibpromma Saowaluck ,   Center for Yunnan Plateau Biological Resources Protection and Utilization, College of Biological Resource and Food Engineering, Qujing Normal University, Yunnan 655011, P.R. China, Kumla Jaturong ,   Center of Excellence in Microbial Diversity and Sustainable Utilization, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand, Dai Dong-Qin ,   Center for Yunnan Plateau Biological Resources Protection and Utilization, College of Biological Resource and Food Engineering, Qujing Normal University, Yunnan 655011, P.R. China, Karunarathna Samantha C. ,   Center for Yunnan Plateau Biological Resources Protection and Utilization, College of Biological Resource and Food Engineering, Qujing Normal University, Yunnan 655011, P.R. China,   National Institute of Fundamental Studies, Kandy, Sri Lanka, Wang Xiao-Yan ,   Edible Fungus Research Institute of Hunan Province, Changshan 410013, P.R. China,   Luliang Cuan Lu Yuan Mushroom Co., LTD, Luliang 655607, P.R. China
Published: November 2023

During t he investigation of Basidiomycetes at Qujing, Yunnan Province, China, some interesting mushroom specimens were collected at the Qujing Normal University premises. Based on their unique morphology, we preliminarily identified them as Agaricus species. Further analyses based on internal transcribed spacer (ITS) region and micro-morphological characteristics confirmed that the collected specimens represent two known species viz. A. andrewii and A. xanthodermulus belonged to Agaricus sections Agaricus and Xanthodermatei, respectively. These two species are reported here as new records to China. Full Descriptions, color plates, and a phylogenetic tree to show the placement of two species are provided.
Synergetic Effect Of Ternary Mixture Of Nano Silicon Carbide-Polyvinyl Alcohol-Lithium Sulfate On Early Strength Of Cement
Authors:   Department of safety science and engineering, Anhui University of Science and Technology, China, Liu Jian ,   Key Laboratory of Mine Safety and High Efficient Mining Jointly built by Province and Education Ministry, Anhui University of Science and Technology, China, Rong Jingwen ,   Department of safety science and engineering, Anhui University of Science and Technology, China, Ji Xiaoli ,   Department of chemical engineering, Anhui University of Science and Technology, China, Chen Boyang ,   Department of safety science and engineering, Anhui University of Science and Technology, China, Wang Yuan ,   Department of safety science and engineering, Anhui University of Science and Technology, China
Published: November 2023

T o solve the problems of low compressive strength and unstable sealing capability of traditional hole sealing materials in the early stage of underground coal mines, a new cement-based sealing material was developed in this study by mixing ordinary Portland cement with nanomaterial, water-soluble polymer and lithium salt as additives. The early strength and the microstructure evolution of the as-prepared cement material were investigated with uniaxial compression test, scanning electron microscope (SEM), thermogravimetric analysis and X-ray diffraction (XRD). The results show that the ternary composite material (nano silicon carbide, polyvinyl alcohol and lithium sulfate) can effectively improve the early strength of cement. The 1-day compressive strength increased from 8.56 to 14.21 MPa, pointing out an improvement rate of 66.00%. It can be seen from the SEM images that a large number of fibrous C-S-H crystals and rod-shaped AFt crystals formed in the ternary composite cement sample. The nanosized silicon carbide (SiC) can accelerate the generation of hydration products through forming nucleation sites. As a dispersing agent polyvinyl alcohol (PVA) can effectively prevent the agglomeration of SiC nanoparticles and the formation of cement particle flocculation structure. On the other hand, the lithium cations and the sulfate anions of lithium sulfate could penetrate the hydration film structure and react with the hydration product Ca(OH)2, respectively, which promotes the hydration reaction. The promotion effect of the ternary composite material on the formation of hydration products results in a clearly improved early strength of the new cement-based sealing material.
First Report of Curvularia hominis as a Causal Agent of Riceberry Rice Leaf Spot in Northern Thailand
Authors:   Graduate School, Chiang Mai University, Chiang Mai 52000, Thailand, Chaisarn Dorkrak , Suwannarach Nakarin ,   Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai 52000, Thailand,   Center of Excellence in Microbial Diversity and Sustainable Utilization, Chiang Mai University, Chiang Mai 52000, Thailand, Lumyong Saisamorn ,   Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai 52000, Thailand,   Center of Excellence in Microbial Diversity and Sustainable Utilization, Chiang Mai University, Chiang Mai 52000, Thailand,   Academy of Science, The Royal Society of Thailand, Bangkok 10300, Thailand, Youpensuk Somchit ,   Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai 52000, Thailand, Pathom-aree Wasu ,   Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai 52000, Thailand,   Center of Excellence in Microbial Diversity and Sustainable Utilization, Chiang Mai University, Chiang Mai 52000, Thailand
Published: November 2023

L eaf spot disease was observed on Riceberry rice (Oryza sativa L.) in the San Pa-Tong District of Chiang Mai Province, northern Thailand during the rainy season in September 2015. A single strain of Curvularia was isolated from disease symptoms. To confirm its pathogenicity, the isolated fungus was used to inoculate healthy Riceberry rice leaves. Subsequently, the same fungus was re-isolated from the leaves, displaying similar symptoms to those observed in the field. Morphological characteristics and multi-gene phylogenetic analyses of the internal transcribed spacers (ITS) and large subunit (LSU) of nuclear ribosomal DNA, glyceraldehyde-3-phosphate dehydrogenase (GPDH), and the RNA polymerase II second largest subunit (RBP2) genes were applied to identify the pathogen as Curvularia hominis. This finding represents the first report of C. hominis as the causal agent of leaf spot disease on Riceberry rice in Thailand.