bluuebunny/crossref_metadata_2025 huggingface dataset:
MODELOS DE CONSTATAÇÃO DE PROVAS EM LIDES DE IMPROBIDADE ADMINISTRATIVA E CONFISCO ALARGADO NO PROCESSO PENAL
Authors: BERTONCINI MATEUS EDUARDO SIQUEIRA NUNES , GUARAGNI FÁBIO ANDRÉ , DE MACEDO GUSTAVO HENRIQUE ROCHA
Published: April 2020

O ensaio afirma a descoberta da verdade como condição imprescindível para a efetividade da jurisdição, e, consequentemente, do Direito. Admitindo a impossibilidade de obtenção de verdade absoluta, apresentam-se os principais modelos de constatação de provas, relacionando critérios metodológicos para a eleição do standard mais adequado a cada tipo de processo. Como resultado, conclui-se que o modelo da probabilidade prevalente é o mais adequado para julgamento de ações de improbidade administrativa. Defende-se, por fim, que os mesmos argumentos levam à utilização do standard da probabilidade prevalente à perda de bens incompatível com o patrimônio do criminoso, recentemente incluída no Código Penal. Palavras-chave: standards probatórios. Improbidade administrativa e confisco alargado. Probabilidade prevalente.
FRATERNIDADE E SUSTENTABILIDADE: diálogo necessário para formação de uma consciência ecológica e construção de uma Sociedade Fraterna
Authors: DARCANCHY MARA VIDIGAL , DE SOUZA MARIA CLÁUDIA DA SILVA ANTUNES , DA SILVA ILDETE REGINA VALE
Published: April 2020

O objetivo deste artigo “Fraternidade e Sustentabilidade: diálogo necessário para formação de uma consciência ecológica e de construção de uma Sociedade Fraterna” é aproximar e relacionar ideias que permitam (re)pensar o projeto civilizatório, pensando em um projeto cultural comum à Humanidade com fundamento nas Constituições dos Estados nacionais. A justificativa da pesquisa está no fato do Planeta Terra ser o único espaço comum que garante a continuidade da existência da Humanidade, considerando o processo de deterioração que ameaça a própria sobrevivência. A metodologia na investigação foi o método indutivo e na fase de tratamento de dados, o método cartesiano. Palavras-chave: Fraternidade;  Sustentabilidade; Sociedade Fraterna.
Bringing Virtual Reality From Clinical Trials to Clinical Practice for the Treatment of Eating Disorders: An Example Using Virtual Reality Cue Exposure Therapy
Authors: Brown Theresa , Nauman Vogel Emily , Adler Sarah , Bohon Cara , Bullock Kim , Nameth Katherine , Riva Giuseppe , Safer Debra L , Runfola Cristin D
Published: April 2020

Novel treatment options for eating disorders (EDs) are critically needed to enhance treatment outcomes and reduce the rates of treatment dropouts. On average, only 50% of individuals receiving evidence-based care remit, whereas 24% drop out before treatment completion. One particularly promising direction involves integrating virtual reality (VR) with existing evidence-based treatments (EBTs) such as cue exposure therapy (CET). Across psychiatric disorders, VR-based interventions are demonstrating at least preliminary efficacy and noninferiority to traditional treatments. Furthermore, VR technology has become increasingly portable, resulting in improved acceptance, increased access, and reductions in cost. However, more efficient research processes may be needed to uncover the potential benefits of these rapid technological advances. This viewpoint paper reviews existing empirical support for integrating VR with EBTs (with a focus on its use with EDs) and proposes key next steps to more rapidly bring this innovative technology-based intervention into real-world clinic settings, as warranted. VR-CET for EDs is used to illustrate a suggested process for developing such treatment enhancements. We recommend following a deployment-focused model of intervention development and testing to enable rapid implementation of robust, practice-ready treatments. In addition, our review highlights the need for a comprehensive clinical protocol that supports clinicians and researchers in the implementation and testing of VR-CET and identifies key missing protocol components with rationale for their inclusion. Ultimately, this work may lead to a more complete understanding of the full potential of the applications and integrations of VR into mental health care globally.
Exploring the Hierarchical Influence of Cognitive Functions for Alzheimer Disease: The Framingham Heart Study (Preprint)
Authors: Ding Huitong , An Ning , Au Rhoda , Devine Sherral , Auerbach Sanford H , Massaro Joseph , Joshi Prajakta , Liu Xue , Liu Yulin , Mahon Elizabeth , Ang Ting FA , Lin Honghuang
Published: April 2020

BACKGROUND

Although some neuropsychological (NP) tests are considered more central for the diagnosis of Alzheimer disease (AD), there is a lack of understanding about the interaction between different cognitive tests.

OBJECTIVE

This study aimed to demonstrate a global view of hierarchical probabilistic dependencies between NP tests and the likelihood of cognitive impairment to assist physicians in recognizing AD precursors.

METHODS

Our study included 2091 participants from the Framingham Heart Study. These participants had undergone a variety of NP tests, including Wechsler Memory Scale, Wechsler Adult Intelligence Scale, and Boston Naming Test. Heterogeneous cognitive Bayesian networks were developed to understand the relationship between NP tests and the cognitive status. The performance of probabilistic inference was evaluated by the 10-fold cross validation.

RESULTS

A total of 4512 NP tests were used to build the Bayesian network for the dementia diagnosis. The network demonstrated conditional dependency between different cognitive functions that precede the development of dementia. The prediction model reached an accuracy of 82.24%, with sensitivity of 63.98% and specificity of 92.74%. This probabilistic diagnostic system can also be applied to participants that exhibit more heterogeneous profiles or with missing responses for some NP tests.

CONCLUSIONS

We developed a probabilistic dependency network for AD diagnosis from 11 NP tests. Our study revealed important psychological functional segregations and precursor evidence of AD development and heterogeneity.
Experiences With Developing and Using Vital Sign Telemonitoring to Support Mobile Nursing in Rural Regions: Feasibility and Usability Study (Preprint)
Authors: Schweitzer Marco , Huber Lukas , Gorfer Thilo , Hörbst Alexander
Published: April 2020

BACKGROUND

Modern information and communication technology has the potential to support mobile care in rural regions such as the Alpine region, which is characterized by long distances or even physically unreachable areas.

OBJECTIVE

This study investigated the potential of supporting mobile nursing organizations in rural regions with the use of mobile telemonitoring systems in a case study setting.

METHODS

As a subproject of the European Union–funded project INTESI, the VITAl parameter MOnitoring (VITAMO) project gathered stakeholders’ requirements for telemonitoring support of mobile care in rural regions and then developed and implemented a prototype system that was used for a 3-month test period with a local nursing organization in Austria. Log analysis, surveys, and interviews were used to evaluate the system according to the Technology Acceptance Model. The focus was technology assessment and user satisfaction of both patients and nurses.

RESULTS

Participants were provided Bluetooth devices to measure blood pressure, body weight, and blood glucose and to track activity. They also received a tablet with a mobile internet connection to see the results. The nurses were able to access the results remotely. Regularly executed speed tests and log analysis demonstrated the availability of high-speed mobile internet in the rural test region. Log analysis, surveys, and interviews revealed the suitability of the technology environment and showed that the system was easy to use and potentially useful. The perceived usefulness for supporting mobile care was rated meaningfully low, and the frequency of nurses using the tool declined continuously over the field test period. Further group discussions investigated this issue.

CONCLUSIONS

While the technology environment with mobile internet, Bluetooth devices, and smart vital sign monitoring devices was adequate and suitable to support mobile nursing in rural regions, the potential benefit for the nursing organization could not be confirmed. Further analysis revealed that operational care processes did not follow a well-defined care strategy. Technology has the potential to leverage the available environment for developing meaningful solutions. These experiences could contribute to further investigations that need to identify and analyze existing mobile care processes at an organizational level.

INTERNATIONAL REGISTERED REPORT

RR2-10.2196/
The Analysis of Chinese Convertible Bond Market
Authors: Tian Yuxin , Chen Jun
Published: April 2020

Convertible bond is a type of hybrid security with both bond- and stock-like features. The Chinese market of convertible bonds has developed dramatically during the last decade. This paper will conduct a comprehensive analysis of this market. Firstly, a brief introduction of convertible bond and the historical evolution of this market in China is presented, then we analyze various investment risks related to convertible bonds. Next, this paper proposes the basic valuation model for convertible bonds, which is the Black-Scholes model and modifies it by taking the delusion effect of conversion into account, leading to the Gailai-Schneller model. In addition, the differences of the outcomes obtained by these two models are compared and analyzed based on the pricing of Shanghai Electric convertible bond. In the sixth part, this paper mainly explains two types of applications of convertible bonds in portfolio management. In the end, several problems existing in Chinese convertible market as well as some suggestions for solving them are discussed.
PEMANFAATAN WISATA MATA AIR YANG DIKELOLA OLEH BUMDES DI DESA BELIK
Authors: Dhesinta Rini Wafia Silvi , Tarigan Muhammad Insan
Published: April 2020

Belik Village has the potential to be developed into a tourist area or tourist village. The potential possessed by Belik Village is a spring located in a bamboo forest. Furthermore, the location of the bamboo forest is on a 4 hectare village treasury land so that the management and utilization of the spring can be used as a source of village cash receipts. The source of the springs will sound the gurgling among the bamboo forests located in Jibru Village, Belik Village so that it becomes a selling point for the development of ecotourism. The method used is descriptive qualitative and data obtained through interviews and field observations. Constraints experienced by village officials to the extent that they have not been able to establish a tourist village are caused by several things including (1) the non-establishment of a Village Regulation governing the establishment of a Bumdes; (2) there is no roadmap for tourism villages yet; (3) inadequate human resource capacity; and (4) limited innovations that support the tourism sector. Seeing the existing potential and some problems in Belik Village, Trawas District, intensive and inclusive assistance is needed to support the realization of the development of a tourism village based on the superior potential of the village. Keywords: tourist village, Bumdes, Village Regulation, Belik Village, Trawas District
Efeitos da terapia craniossacral e a mobilização uterina no alívio da dismenorreia primária: um estudo piloto
Authors: Canário Mariza Barbosa , Gilly Daphne
Published: April 2020

Introdução: a dismenorreia primária, conhecida também como cólica menstrual, é uma dor que ocorre antes ou durante o período menstrual e se caracteriza por diversos sintomas, entre eles dor no baixo ventre, cefaleia, náuseas, tontura e até desmaios. Objetivo: avaliar os efeitos da Mobilização Uterina associada ou não à Terapia Craniossacral no alívio da dismenorreia primária e seus sintomas associados. Metodologia: trata-se de um estudo piloto realizado em quatro fases. A primeira consistiu na aplicação de quatro questionários (avaliativo, instrumento de rastreamento da síndrome pré-menstrual, avaliação e impacto da dismenorreia primária e cefaleia); em seguida, foi realizada a randomização de um total de oito voluntárias, quatro para o Grupo Controle (GC), que recebeu apenas a Mobilização Uterina, e quatro ao Grupo Experimental (GE), que, associada, recebeu a Terapia Craniossacral. O terceiro passo se caracterizou pela aplicação do questionário de satisfação, e a quarta etapa foi a entrega de um questionário de acompanhamento para que a voluntária respondesse ao fim do ciclo menstrual seguinte. Resultados: verificou-se que, no GE no qual foi aplicada a associação das duas técnicas, houve uma redução maior de sintomas associados que no GC. Conclusão: são necessários novos estudos com uma amostra maior para uma melhor análise dos resultados da aplicação dessas técnicas associadas, a fim de que sejam desenvolvidos protocolos de tratamentos fisioterapêuticos da dismenorreia primária e seus sintomas associados.
Efeito de um protocolo baseado no Método Pilates sobre mobilidade, equilíbrio e risco de quedas em idosas da comunidade: ensaio clínico
Authors: Ferreira Laís Leite , Ferreira Mônica Beatriz
Published: April 2020

Introdução: entre os distúrbios ocorridos pelo processo de envelhecimento, o equilíbrio corporal pode ser afetado, o que gera grandes impactos na autonomia social, predispondo a queda e trazendo imobilidade corporal e medo de cair ao idoso. Entre as propostas de intervenção, surge o Método Pilates (MP) com o intuito de trabalhar e melhorar a força muscular, o equilíbrio e a postura. Objetivo: este estudo teve o propósito de analisar o efeito de um protocolo baseado no MP sobre a mobilidade, o equilíbrio e o medo de cair em idosas da comunidade. Materiais e Métodos: trata-se de um ensaio clínico controlado aleatorizado, do qual participaram 29 idosos do sexo feminino, sendo o grupo controle (GC) formado por 15 participantes e o grupo experimental (GE) por 14 participantes. Foram avaliados os dados sociodemográficos (idade, estado civil e escolaridade), os testes Timed up and Go (TUGT), Teste do Alcance Funcional (TAF) e a Escala de eficácia de quedas (FES-I-BRASIL). Após a intervenção com o protocolo baseado no MP, ambos os grupos foram reavaliados. Resultados: houve melhoras significativas no GE após a intervenção nos parâmetros do TUGT (p=0,003) e no FES-I-BRASIL (p=0,027), mas o resultado não foi significativo no teste TAF (p=0,237). Ao comparar o GC com o GE após a intervenção, verificaram-se diferenças significativas nos parâmetros TUGT (p=0,002) e TAF (p=0,030). Conclusão: o protocolo utilizado baseado no MP evidenciou melhoras na mobilidade, no medo de cair e também no equilíbrio em idosas da comunidade, demonstrando ser um método efetivo para a diminuição dos riscos de queda.Palavras-chave: Acidentes por quedas; Equilíbrio postural; Técnicas de exercício e de movimento
Capacidade funcional de idosos acompanhados pela fisioterapia de uma unidade de Atenção Primária à Saúde
Authors: Santos Carine Sousa dos , Collares Patrícia Moreira Costa , Melo Anairtes Martins de , Moraes Gerídice Lorna Andrade de , Lacerda Maria Raquel Lima , Santos Danielle Hortencio Pereira dos
Published: April 2020

Introdução: a avaliação da capacidade funcional obtém foco no exame do avaliado e objetiva indicar o nível máximo de funcionalidade que um indivíduo pode atingir em um dado domínio em dado momento, é um indicador de saúde que se relaciona com a qualidade de saúde e aspectos biopsicossociais. Objetivo: avaliar a capacidade funcional dos idosos acompanhados por uma unidade de Atenção Primária à Saúde pela Fisioterapia e descrever o perfil sociodemográfico e familiar e os dados antropométricos dos entrevistados. Materiais e métodos: realizou-se um estudo transversal, descritivo, com abordagem quantitativa no período de dezembro de 2018 a fevereiro de 2019 em Fortaleza/CE. Coletaram-se dados de 35 idosos utilizando um questionário acerca do perfil sociodemográfico e familiar dos pesquisados e a Short Physical Performance Battery. Resultados: na amostra, houve predomínio de mulheres, entre 60 e 69 anos, casadas, domésticas e sedentárias. A maioria das entrevistadas está com sobrepeso, entretanto a minoria apresentou sarcopenia. Quanto à capacidade funcional, predomina moderado desempenho físico, tendo o pior resultado a etapa de sentar-levantar do teste. Conclusões: a avaliação da capacidade funcional demonstrou a extratificação de idosos em vulnerabilidade física, requerendo o desenvolvimento de ações de intervenção em grupos ou projetos terapêuticos no território.Palavras-chave: Idoso; Atenção Primária à Saúde; Fisioterapia.
THORACIC RADIOLOGY
Authors: Editorial Artiсle
Published: April 2020

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IMAGING IN ONCOLOGY
Authors: Editorial Artiсle
Published: April 2020

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PROSPECTIVE PRIMARY SCHOOL TEACHERS’ ACTIVITIES WHEN DEALING WITH MATHEMATICS MODELLING TASKS
Authors: Viseu Floriano , Martins Paula Mendes , Leite Laurinda
Published: April 2020

The current teaching of mathematics is guided by recommendations that suggest the implementation of various activities in order to raise the understanding of mathematical knowledge. This diversity is related to the characteristics of the tasks proposed in the learning contexts. Among all tasks, the modelling ones call for the application of activities through different representations. So, it is important that teacher training courses promote experiences involving prospective teachers with this type of task. Based on this assumption, we intend to identify the activities that prospective primary school teachers perform in solving modelling tasks, the difficulties experienced in these tasks and the value of the models they determine. From the analysis of the resolutions of two tasks, we find that the prospective teachers translate the information of the data available in tables through graphs and analytical expressions. Some discuss models that determine which best fits the data. In the activities carried out, difficulties arise in determining the proportionality constant that best translates the problem situation, discussing the reasonableness of the values generated by the model, and sketching the graph of the model that best fits the experimental data. As for the usefulness of the model they determine, few prospective teachers are predicting outcomes.
Infección por virus HTLV-1/2 confirmada por serología y detección de provirus en pacientes ecuatorianos de paraparesis espástica tropical
Authors: Mosquera Carmen , Aspiazu Elvia , De Waard Jacobus H. , Garcia-Bereguiain Miguel Angel
Published: April 2020

Introduccion: La infección con el virus linfotrópico de células T humano (HTLV) de tipo 1 y 2 es endémica en América del Sur. Existen muy pocos reportes clínicos de este retrovirus en pacientes de Ecuador y nunca confirmaron la presencia del virus con el aislamiento o la detección de su ADN. Esta infección se encuentra desatendida por las autoridades de salud pública, sin que existan estudios epidemiológicos de prevalencia a nivel del país. Objetivos: Este estudio tiene como objetivo la detección de infección por HTLV -1/2 en individuos sintomáticos de paraparesis espástica tropical (TSP) utilizando por primera vez en Ecuador diagnóstico serológico y la detección del provirus por biología molecular.Diseño del estudio. Se tomaron muestras de nueve pacientes con un diagnóstico de mielopatía y sospechoso de TSP, que fueron analizadas para la detección del virus HTLV-1/2 usando tres metodologías: ELISA comercial, ensayo de inmunofluorescencia indirecta (IF) y PCR anidada. Resultados: Cinco de los 9 (55.5%) pacientes fueron positivos tanto para la prueba de ELISA como para IF y PCR anidada. Conclusión: La alta prevalencia de infección por HTLV-1/2 entre individuos sintomáticos de mielopatía muestra la endemicidad de este retrovirus en Ecuador, la asociación de HTLV-1/2 con TSP y la necesidad de implementar estrategias de control y prevención para evitar la diseminación de esta enfermedad infecciosa desatendida.
Polimorfismos IL1B-511 y TNF-A-308 en una población infectada con Helicobacter pylori de una zona de bajo riesgo de cáncer gástrico en Nariño-Colombia
Authors: Rosero-Rojas Stephany Carolina , Chaleal-Cultid Javier Antonio , Pazos-Moncayo Álvaro Jairo , Rosero-Galindo Carol Yovanna
Published: April 2020

Objetivo: Estudiar los polimorfismos IL1B-511 y TNF-A-308 asociaciados a lesiones precursoras de cáncer gástrico (CG) en una población infectada con Helicobacter pylori (H. pylori) de bajo riesgo de CG de Nariño. Material y método: De 105 pacientes con síntomas de dispepsia se incluyeron 81 infectados por H. pylori, (n=63) con gastritis no atrófica y (n=18) con lesiones precursoras de CG de Tumaco: población de bajo riesgo de CG. Las lesiones gástricas se clasificaron por el sistema de Sydney y H. pylori por tinción de Giemsa. Los polimorfismos de IL1B-511 y TNF-A-308 se genotipificaron por PCR-RFLP’s. Los polimorfismos y su asociación con lesiones gastricas se evaluaron por análisis bivariado y regresión logística binomial. Resultados: Los pacientes portadores del alelo mutante T (IL-1B-511) no se encontraron a riesgo de lesiones precursoras de malignidad (OR=0,7). No se calculó el OR para TNF-A-308, por fijación del alelo normal G. Ser hombre y estar infectado por H. pylori incrementa 4,3 veces el riesgo de presentar lesiones precursoras de CG y no estar vinculado al régimen de salud aumenta 6,7 veces el riesgo de atrofia gástrica, (OR=4,27 y OR=6,72), respectivamente. Conclusión: El alelo mutante T (IL-1B-511) es un biomarcador de resistencia de los pobladores de Tumaco, de bajo riesgo de CG e infectados con H. pylori a padecer lesiones precursoras de CG.
Diagnóstico microbiológico de artritis séptica en niños usando botellas de hemocultivos como un método alternativo
Authors: Atehortúa Santiago , Woodcock Santiago , Naranjo Julian , Faraco Francisco , Uribe Rios Alejandro
Published: April 2020

Introducción: La artritis séptica (AS) se define como la infección del espacio articular que afecta cualquier articulación, es más frecuente en niños menores de 5 años y su principal causa es la diseminación hematógena. El diagnóstico etiológico es difícil en niños, logrando aislamiento en menos de la mitad de los casos. Se evaluó el rendimiento diagnóstico de la botella de hemocultivo (BHC) como medio alternativo para la siembra del líquido sinovial comparado con los medios convencionales (MC). Metodología: Estudio de cohorte prospectivo realizado en centro de tercer nivel de 2011-2016, niños de 0 a 12 años con diagnóstico clínico de artritis séptica y disponibilidad de las dos muestras tomadas en cirugía. Resultados: Ingresaron 60 pacientes, masculinos 56%, mediana de edad 48 meses y tiempo de síntomas 58 horas (48-192); 33,3% con antecedente de trauma; 30% recibieron antibióticos previos. Articulaciones afectadas: cadera 44%, rodilla 28% y tobillo 18%. En 39 pacientes (65%) se tomaron hemocultivos; de estos 19 (49%) fueron positivos, todos para S. aureus. Se obtuvo confirmación en líquido sinovial por cualquier método en 27 pacientes (45%), positivos en ambos 21,6%, en MC 13,3% y en BHC 10%, los microorganismos más frecuentes SAMS 21,6%, SAMR 8,3%, S. pyogenes 3,3%, SEMR 3,3%, S. pneumoniae 1,6%, N. meningitidis 1,6%, no se aisló K. kingae. El tratamiento antibiótico más utilizado fueron los betalactamicos, mediana de estancia 18(12-25,5) días, mortalidad del 3,3%. Conclusión: Las BHC son un complemento al medio sólido convencional y aumentaron la confirmación etiológica de artritis séptica del 35% al 45%.
Predicción temporal de CD4+ en 80 pacientes con manejo antirretroviral a partir de valores de leucocitos
Authors: Rodríguez-Velásquez Javier , Prieto-Bohórquez Signed , Pérez-Díaz Carlos , Correa-Herrera Catalina , Soracipa-Muñoz Yolanda , Jattin-Balcázar Jairo , David-Ibarra Andrés
Published: April 2020

Objetivo: establecer una metodología predictiva de aplicación clínica de recuentos de CD4+ en rangos de interés clínico a partir del recuento absoluto de leucocitos.Metodología: a partir de los valores secuenciales de leucocitos y linfocitos CD4+ de 9 pacientes, se observaron patrones matemáticos que posteriormente fueronaplicados en un estudio ciego con 71 casos para confirmar su capacidad predictiva, midiendo porcentajes de especificidad y sensibilidad. Resultados: se determinaron cinco patrones matemáticos que predicen en el 99% de los casos los distintos recuentos de CD4+ a partir de recuentos de leucocitos con valores de especificidad y sensibilidad del 99%. Conclusiones: los patrones matemáticos encontrados entre recuento de leucocitos y CD4+ sugieren que este fenómeno prácticamente es determinista.
Análisis de parámetros de calidad y de costos, de uso del catéter venoso central de inserción periférica frente al catéter de inserción central, en población pediátrica del Hospital Universitario del Valle, Cali, Colombia. 2011-2014
Authors: Gallego-Aguirre Lady , Orozco-Hernández Blanca Enir
Published: April 2020

Objetivo: estimar parámetros de calidad y de costos en el procedimiento de inserción de Catéter Venoso Central y el Catéter Venoso Central de inserción periférica. Metodología: Se evaluaron las historias de niños (edad 31 días -15 años ), que ingresaron al Hospital Universitario del Valle, entre enero de 2011 y diciembre de 2014, que requirieron canalización de una vena central. Se evaluaron variables demográficas, de calidad y se estimaron costos de ambos procedimientos. Resultados: Se evaluaron 100 procedimientos de inserción Central y 100 de inserción periférica, los últimos tuvieron menor tiempo de espera, se realizaron en la habitación, no requirieron ayuno, ni traslado al quirófano, a un menor costo, lo cual impactó la oportunidad de administración de tratamiento farmacológico, la evolución y la estancia hospitalaria. Conclusiones: Se recomienda que el procedimiento de inserción periférica sea la primera elección en niños que requieran tratamientos endovenosos mayores acinco días, para esto es necesario conformar un grupo que supervise el funcionamiento de los catéteres y brinde educación continua al personal de salud de los servicios de hospitalización y a familiares, contar con una sala de procedimiento para la inserción del PICC que brinde seguridad y adecuado manejo del dolor.
Linfohistiocitosis hemofagocítica por Histoplasma capsulatum en paciente con trasplante renal
Authors: Camargo-Salamanca Alejandro , Patino-Jaramillo Nasly Gisell , Lopez-Prieto Liliana , Garcia-Lopez Andrea Elena , Giron-Luque Fernando
Published: April 2020

La linfohistiocitosis hemofagocítica (LHH) por Histoplasma capsulatum, presentación rara de la histoplasmosis diseminada, es causada por la fagocitosis de las células hematopoyéticas por macrófagos tisulares. Presentamos el caso de un paciente masculino de 44 años con trasplante renal que asiste por fiebre sin otra sintomatología. Inicialmente se obtiene una gota gruesa positiva para P. vivax, iniciando manejo antimalárico. A los 2 días de tratamiento, el paciente presenta disfunción multiórganica, se rectifica diagnóstico en centro de referencia reportando en extendido de sangre periférica la presencia de levaduras de H. capsulatum en polimorfonucleares, resultado confirmado con prueba de inmunodifusión. Se ajusta manejo, pero el paciente fallece. El diagnóstico de infecciones por gérmenes inusuales con presentaciones inespecíficas es un reto en pacientes con inmunosupresión.
Bacteriemia por Clostridium sordellii en paciente con neoplasia gastrointestinal. Reporte de caso y revisión de literatura
Authors: Bravo-Ojeda Juan , Gomez-Quintero Carlos , Pescador-Vargas Luz , Suarez-Tirado Jenifer
Published: April 2020

La bacteriemia por Clostridium sordellii es infrecuente y usualmente se origina a partir de infecciones de etiología generalmente ginecológica y puerperal, con unamortalidad de aproximadamente el 70%. Existen pocas herramientas para el diagnóstico rápido y oportuno, siendo así la experiencia de tratamiento para este germen muy limitada en otros escenarios, lo que probablemente sea la causa de su alta mortalidad. Presentamos una paciente con antecedente de masa abdominal expansiva de larga data, con diagnóstico por histopatología e inmunohistoquimica compatibles con tumor del estroma gastrointestinal (GIST por sus siglas en inglés) y estudios de extensión que confirman compromiso metastásico hepático, en quien se documenta bacteriemia por Clostridium sordellii.
Recognizing generalized Sierpiński graphs
Authors: Imrich Wilfried , Peterin Iztok
Published: April 2020

Let H be an arbitrary graph with vertex set V (H) = [nH] = {l,?, nH}. The generalized Sierpi?ski graph SnH , n ? N, is defined on the vertex set [nH]n, two different vertices u = un ?u1 and v = vn ? v1 being adjacent if there exists an h? [n] such that (a) ut = vt, for t > h, (b) uh ? vh and uhvh ? E(H), and (c) ut = vh and vt = uh for t < h. If H is the complete graph Kk, then we speak of the Sierpi?ski graph Sn k . We present an algorithm that recognizes Sierpi?ski graphs Sn k in O(|V (Sn k )|1+1=n) = O(|E(Sn k )|) time. For generalized Sierpi?ski graphs SnH we present a polynomial time algorithm for the case when H belong to a certain well defined class of graphs. We also describe how to derive the base graph H from an arbitrarily given SnH .
Asymptotic properties of solutions of third order difference equations
Authors: Migda Janusz , Migda Małgorzata , Nockowska-Rosiak Magdalena
Published: April 2020

We consider the difference equation of the form ?(rn?(pn?xn)) = anf (x?(n)) + bn. We present sufficient conditions under which, for a given solution y of the equation ?(rn?(pn?yn)) = 0, there exists a solution x of the nonlinear equation with the asymptotic behavior xn = yn + zn, where z is a sequence convergent to zero. Our approach allows us to control the degree of approximation, i.e., the rate of convergence of the sequence We examine two types of approximation: harmonic approximation when zn = o(ns), s ? 0, and geometric approximation when zn = o(?n), ? ? (0, 1).
On a generalized function-to-sequence transform
Authors: Trickovic Slobodan , Stankovic Miomir
Published: April 2020

By attaching a sequence {?n}n?N0 to the binomial transform, a new operator
D? is obtained. We use the same sequence to define a new transform T? mapping
derivatives to the powers of D?, and integrals to D-1?. The inverse
transform B? of T? is introduced and its properties are studied. For ?n =
(-1)n, B? reduces to the Borel transform. Applying T? to Bessel's
differential operator d/dx x d/dx, we obtain Bessel's discrete operator
D?nN?. Its eigenvectors correspond to eigenfunctions of Bessel's differential
operator.
q-binomial formulae of Dixon`s type and the Fibonomial sums
Authors: Chu Wenchang , Kılıç Emrah
Published: April 2020

Cubic sums of the Gaussian q-binomial coefficients with certain weight functions will be evaluated in this paper. To realize this, we will derive two remarkable formulae by means of the Carlitz-Sears transformation on terminating well-poised q-series. As consequences, several summation formulae on Fibonomial coefficients are presented by specializing the value of base q in our q-series identities.
Approximate symmetries and similarity solutions for wave equations on liquid films
Authors: Jamal Sameerah , Paliathanasis Andronikos
Published: April 2020

We study the exact and approximate Lie symmetries for two equations which describe long waves with small amplitude on liquid films. Specifically, we study the 1+2 Benney-Luke and the 1+1 Benney-Lin equations, both from an exact and approximate perspective. To induce approximate symmetries, we show that terms involving derivatives higher than two are necessarily selected as the perturbation parameters. We construct conservation laws for both equations, and illustrate how the approximate point symmetries can be used to determine approximate similarity solutions.
On Mathieu-type series for the unified Gaussian hypergeometric functions
Authors: Parmar Rakesh , Pogány Tibor
Published: April 2020

The main purpose of this paper is to present closed integral form expressions for the Mathieu-type a-series and for the associated alternating versions whose terms contain a generalized p-extended Gauss' hypergeometric function. Related bounding inequalities for the p-generalized Mathieu-type series are also obtained. Finally, a set of various (known or new) special cases and consequences of the results earned are presented.
LncRNA NEAT1 exacerbates non-small cell lung cancer by upregulating EIF4G2 via miR-582-5p sponging
Authors: Zhang Xin , Sun Zhonghua , Zou Yuepei
Published: April 2020

In this study, we aimed to elucidate the role of long non-coding RNA nuclear enriched abundant transcript 1 (lncRNA NEAT1) in non-small cell lung cancer (NSCLC). Quantitative real-time polymerase chain reaction (qRT-PCR) was employed to detect the abundance of NEAT1, microRNA-582-5p (miR-582-5p) and eukaryotic translation initiation factor 4 gamma 2 (EIF4G2). Proliferation, apoptosis, metastasis and glycolytic metabolism were determined by 3-(4,5-dimethylthiazol- 2-yl)-2,5-diphenyltetrazolium bromide (MTT) flow cytometry, transwell assays and fluorescence-based glucose and lactate assay kits. The targets of NEAT1 and miR-582-5p were predicted by the starBase website, and dual-luciferase reporter and RNA immunoprecipitation (RIP) assays were performed to verify these predictions. Western blot analysis was conducted to detect the protein expression of EIF4G2. A xenograft tumor model was built to clarify the role of NEAT1 in vivo. Results showed that NEAT1 interference inhibited proliferation, metastasis and glycolysis, and facilitated the apoptosis of NSCLC cells. MiR-582-5p was a functional target of NEAT1, and the biological influence of NEAT1 intervention on NSCLC cells was alleviated by transfection with anti-miR-582-5p. MiR-582-5p could bind to EIF4G2 messenger RNA (mRNA); it exerted its antitumor role in NSCLC cells by inhibiting EIF4G2. EIF4G2 was regulated by NEAT1/miR-582- 5p signaling. NEAT1 accelerated NSCLC tumor growth via the miR-582-5p/EIF4G2 axis in vivo. In conclusion, NEAT1 affected NSCLC by elevating their malignant potential via the miR-582-5p/EIF4G2 axis.
High number of CD14+B7H4+ monocytes is significantly associated with increased concentrations of IL-4, IL-13, IL-10, and TGF-β1 in tumor microcirculation of lung carcinoma
Authors: Vukovic Jelena , Nikolic Nevena , Karlicic Vukoica , Stanojevic Ivan , Supic Gordana , Jovic Milena , Stefik Debora , Abazovic Dzihan , Vojvodic Danilo
Published: April 2020

Background/Aim. Lung cancer (LC) is one of the leading causes of mortality. Disease progression and advanced disease are characterized by the unprotective immune response due to M2 macrophage polarization, myeloid-derived suppressor cells (MDSC) activity, cytokine imbalance, and regulatory T lymphocyte activity. The aim of this study was to investigate the association between Th1/Th2 cytokines and CD14+B7H4+ monocyte (Mo) number in LC patients. Methods. We investigated principal Th1/Th2 cytokines and CD14+B7H4+ Mo number in blood and tumor microcirculation samples of 41 LC patients (III and IV clinical stage) and 30 healthy participants (control group). Results. The serum concentrations of investigated cytokines in all patients vs. heathy controls did not differ significantly. Stratification in groups according to tumor histology, disease extent, and tumor size revealed significant differences. LC patients with different histology types demonstrated significant differences, both in serum and tumor microcirculation samples. The presence of metastasis was associated with increased IFN-?/IL-4 in blood and increased IL-13 in tumor microcirculation samples. Tumor microcirculation samples of the largest tumors were characterized by the Th2 cytokine profile. Investigation of CD14+B7H4+ Mo in blood samples demonstrated a significant association of extreme value of this cell population with elevated IL-2/IL-13. Patients with the highest CD14+B7H4+ Mo number in tumor microcirculation samples demonstrated significant increments of IL-4, IL-13, IL-10, and TGF-?1. Conclusion. LC patients demonstrated polarization of cytokine response associated with microenvironment origin, tumor histology type, tumor size, and disease extent. The highest number of CD14+ B7H4+ monocytes is significantly associated with the Th2 cytokine profile.
Lost in Translation? Analysts' Forecasts of Cross-Listed Firms
Authors: Cho Hyunkwon , Muslu Volkan , Koo Minjae
Published: April 2020

The level of difficulty for U.S. analysts in the native language of a cross-listed firm increases their forecast errors. The association is decreased by analyst experience and analyst fluency in the language of the cross-listed firms. The association is also decreased for countries using IFRS and those with higher financial reporting quality. Investors react more strongly to forecasts for firms that present greater language difficulty to analysts. Overall, our findings suggest that the language difficulty of cross-listed firms is associated with a poor information environment and capital-market-related costs.
Validación del instrumento de evaluación de desempeño de un sistema de gestión de calidad en una institución de educación superior
Authors: Sotelo Asef Jesús Guillermo , Sosa Álvarez María Concepción , Carreón Gallegos Ernesto
Published: April 2020

En el entendido de que una institución educativa es también una organización cuya tarea sustantiva es la proporción de un servicio que busca el aprendizaje del estudiante a través de las actividades que en su totalidad ofrece, la percepción de los trabajadores al respecto es base para la maduración de un sistema de gestión de la calidad que trascienda en sus procesos con la intención de generar mejores resultados. Bajo este tenor, el objetivo de este estudio radicó en diseñar y validar una herramienta para el monitoreo del estatus que guarda una institución de educación superior, en ese sentido y alineado a los estatutos de la norma de calidad ISO 9001:2015.

Para ello, se elaboró un instrumento para conocer la percepción de los trabajadores con respecto a lo mencionado, de tal forma que el resultado obtenido anule los sesgos derivados de la aplicación de otras herramientas, tales como las listas de cotejo que la misma norma provee, las cuales no están alejadas del todo del criterio y otros contaminantes, como marcos de referencia o disposición y ánimo del que audita o mide. El diseño de la investigación se clasificó en el tipo instrumental, y el documento de medición en la tipología escala. Se definieron sus propiedades métricas de contenido, constructo y confiabilidad a una muestra de 133 trabajadores universitarios. La estructura final de dicho instrumento se conformó por 42 ítems, distribuidos en cinco dimensiones, como resultados se obtiene que el instrumento diseñado después de su validación estadística cumple con los criterios establecidos siento este un instrumento válido para su aplicación en la práctica.
Efektifitas metode belajar renang dengan bantuan teman untuk meningkatkan kepercayaan diri atlit
Authors: Sin Tjung Hauw , Hudayani Fakhrina
Published: April 2020

Beberapa atlit mengalami kesulitan dalam melakukan renang gaya dada. Salah satu penyebabnya adalah kurangnya kepercayaan diri atlit dalam melakukannya. Penelitian ini bertujuan untuk meninjau efektifitas metode renang dengan bantuan teman untuk meningkatkan kepercayaan diri Atlit dalam melakukan renang gaya dada. Metode penelitian yang digunakan adalah metode quasi experimen. Populasi pada penelitian ini berjumlah 79 orang atlit renang. Kemudian dilakukan penarikan sampel dengan teknik purposive sampling. Sehingga didapatkan 41 orang yang menjadi sampel penelitian. Intrumen yang digunakan pada penelitian ini adalah instrumen tentang kepercayaan diri. Teknik analisis data yang digunakan adalah teknik t-test. Data dianalisis dalam dua kelompok, yaitu pre-test dan post-test. Perangkat yang digunakan untuk menganalisis data adalah SPSS versi 16. Hasil penelitian ini menunjukkan bahwa metode renang dengan bantuan teman efektif dalam meningkatkan kepercayaan diri atlit dalam berenang gaya dada. Dengan taraf signifikansi 6.42 dan ? = 0.05.
Aprendizagem matemática através da elaboração de problemas em uma escola comunitária rural
Authors: Andreatta Cidimar , Allevato Norma Suely Gomes
Published: April 2020

Neste artigo, apresentamos resultado de uma pesquisa de doutorado realizada com estudantes do 5º ano do Ensino Fundamental de uma Escola Municipal Comunitária Rural, cujo objetivo foi investigar como problemas elaborados pelos estudantes podem contribuir para suas aprendizagens. Os dados foram construídos por meio da observação participante e da análise do enredo textual dos problemas elaborados pelos estudantes em um contexto de aprendizagem que levou em consideração conteúdos desenvolvidos por eles em etapas anteriores da pesquisa. Com abordagem qualitativa, a investigação configura-se como pesquisa-ação, em que os dados foram submetidos à análise textual discursiva a partir dos registros da elaboração dos problemas e das observações. Os resultados mostram que os problemas elaborados pelos estudantes estiveram relacionados, em sua maior parte, às operações fundamentais da Matemática, especialmente a adição e multiplicação como potencial para desenvolver aspectos da criatividade e da criticidade dos estudantes.

Palavras-chave: Educação Matemática. Elaboração de Problemas. Aprendizagem discente.
Spectral Theory of Singular Hahn Difference Equation of the Sturm-Liouville Type
Authors: Allahverdiev Bilender P. , Tuna Hüseyin
Published: April 2020

In this work, we consider the singular Hahn difference equation of the Sturm-Liouville type. We prove the existence of the spectral function for this equation. We establish Parseval equality and an expansion formula for this equation on a semi-unbounded interval.
Indicadores de qualidade em terapia nutricional enteral em uma unidade de terapia intensiva no interior de Rondônia
Authors: Posso Priscila Nayara Vasconcelos , Chagas Patrícia de Souza , Kopper Andressa Magali , Da Silva Rittiela Rocha , Cavalcante Aline Brito Lira , Bonfá Andreska Lara Silva , Rodrigues Briany Soares , Negreiros Emanuelle Nogueira , De Lima Emilly Karine Ventura , Lima Angela Antunes de Morais
Published: April 2020

Objetivo: Aplicar e avaliar os Indicadores de Qualidade Terapia Nutricional em pacientes internados nas UTIs Adulto de um Hospital público no interior de Rondônia. Métodos: Estudo de caráter transversal, descritiva, com abordagem quantitativa por meio de dados obtidos em 2019, colhidos junto a fichas de anotações de enfermagem e do setor de nutrição. A amostra foi composta por pacientes de ambos os sexos com idade superior a 18 anos que receberam terapia nutricional enteral (TNE) no período. Resultados: Foram analisados 50 pacientes em uso de TNE exclusivo, com média de idade de 53±19,49 e 59±20,73 anos para homens e mulheres, respectivamente. No período analisado, foi observado que a média de volume prescrito e infundido foi de 1040,02±115,45 ml/dia e 879,31± 134,51 ml/dia, respectivamente. A média de calorias prescritas e infundidas foi de 1586,41±197,94 kcal/dia e 1343,10± 209,09 kcal/dia, respectivamente; e a média de prescrito e infundido de proteínas foi de 86,17±10,16 g/dia e 78,4±10,76 g/dia, respectivamente. A adequação calórica para o grupo de estudo foi de 82,3%±23,6% e a adequação proteica de 87,5%±11,1%. Conclusão: Os IQTN aplicados estavam de acordo com as metas pré-estabele­cidas. Sendo que, ainda são necessários mais treinamentos e conscientização da equipe quanto à TNE.
The Impact of Transformational Leadership on Entrepreneurial Orientation via the Mediating Role of Organizational Learning Capability
Authors: Nofal Razan , Jaradat Mais
Published: April 2020

The current research aims to investigate the effect of transformational leadership on entrepreneurial orientation in Jordanian commercial banks, and whether organizational learning capability mediates the effect of transformational leadership on entrepreneurial orientation. Adopting a quantitative research design, data were collected by means of a questionnaire-based survey of employees in Jordanian commercial banks. Based on 330 usable responses, the results revealed the significant effect of transformational leadership and two of its dimensions (inspirational motivation and intellectual stimulation) on entrepreneurial orientation. Two other dimensions (idealized influence and individualized consideration) did not contribute to entrepreneurial orientation. Additionally, the results showed that transformational leadership has a significant effect on organizational learning capability, and that organizational learning capability in turn affects entrepreneurial orientation. The findings confirm that organizational learning capability fully mediates the effect of transformational leadership on entrepreneurial orientation. A number of recommendations are advanced, the most important of which is that banks should improve and develop managers’ transformational attributes by training them on how to deal with employees in order to increase their entrepreneurial orientation. Banks should also consider improving their learning capability, as this plays a significant role in enhancing and supporting the effect of transformational leadership attributes on entrepreneurial orientation.
Assessment of knowledge and practice of vaccination of dogs against rabies by dog owners in Makurdi, Benue State, Nigeria
Authors: Onyemocho Audu , Moses Agwa , Kisani Aboh , Victoria Omole Namben , Joseph Anejo-Okopi
Published: April 2020

Objective:

Rabies, one of the oldest and fatal infectious diseases known to human race, is transmitted by infected dogs. The global target of zero dog-mediated rabies human deaths has been set for 2030; however, the realization of this goal poses challenges in most low-income countries where rabies is endemic due to weak surveillance. Dogs have been increasingly deployed for domestic uses over the years, especially for security purposes. This study assessed the assessment of knowledge and practice of vaccination of dogs against rabies by dog owners.

Materials and Methods:

A cross-sectional community-based study was employed to study 400 dog owners in Makurdi metropolis through multistage sampling techniques. Sighting of valid dog vaccination card was used as criteria for current vaccination. Bivariate analysis was carried out to establish the relationship between the respondent knowledge of rabies and dog vaccination with significant value set at P < 0.05.

Results:

The mean age of the respondents was 31 (Â ± 0.8) years, majority of them had tertiary and secondary education (40.0% and 39.0%, respectively), 26.0% were traders, and 50.0% were married. Overall, 73.0% of the respondents had good knowledge score, 61.0% had seen at least a rabid dog in their life time, and 74.0% have a history of dog vaccination, but evidence of up to date vaccination of dogs by owners was seen in only 18.0% of all the vaccination cards sighted. The relationship between the educational status of the respondents, their knowledge score, and their dog vaccination was statistically significant (P < 0.05).

Conclusion:

Knowledge of rabies among dog owners in Makurdi was good, but the practice of dog vaccination was poor. Educational status was a good predictor of practice. Awareness campaign on dog vaccination should be strengthened and adequate measures should be put in place at the veterinary hospitals in Makurdi for vaccination of dogs.
Dünyada ve Türkiye'de Güneş, Rüzgar ve Jeotermalde Güncel İktisadi Görünüm
Authors: KOÇASLAN Gelengül
Published: April 2020

Yenilenebilir enerji kaynaklarının,
hızla artan enerji talebini karşılamakta fosil kaynaklara önemli birer
alternatif olduklarına her ne kadar soru işaretleri ile yaklaşılsa da;
dünyadaki gelişmeler bu sorulara cevap niteliğinde karşımızda durmaktadır. Son
yıllarda, teknolojik yenilikler ve bu alanda genişletilen araştırma geliştirme
faaliyetleri bütün dünyanın çözmesi gereken büyük bir problem olarak ortada
duran enerji ihtiyacının karşılanmasında yenilenebilir enerji kaynaklarının
cazibesine özellikle de güneş, rüzgar ve jeotermale bir kez daha dikkat
çekmiştir.Bu makalede dünyada ve Türkiye’deki mevcut durum ve iktisadi
göstergeler; uluslararası gelişmeler ve güncel verilerle değerlendirilmektedir.