bluuebunny/crossref_metadata_2025 huggingface dataset:
Sala de espera: uma estratégia educativa para a promoção em saúde no ambulatório multiprofissional na Amazônia
Authors: Caldas dos Santos Davi , de Andrade Gouvea Tyll Milene , Duarte de Lima João Gabriel , dos Santos Neves Pauliceia , Rodrigues Freitas Josiane , da Gama Araújo Márcia Andréa
Published: September 2024

Objetivo: Descrever a experiência vivenciada sobre a utilização da sala de espera ambulatorial como estratégia educativa para a promoção da saúde aos usuários do SUS. Métodos: Trata-se de um estudo descritivo do tipo relato de experiência, que fez uso da metodologia da teoria da problematização. Resultados: Os resultados foram apresentados de acordo com as etapas da ferramenta Arco de Maguerez, a saber: observação da realidade, identificação dos pontos chaves, teorização, hipóteses de solução e aplicação à realidade. A dinâmica foi realizada na sala de espera do Serviço Ambulatorial da Fundação Pública Hospital de Clínicas Gaspar Vianna (FHCGV) pelo enfermeiro residente em cardiologia para os usuários presentes no ambulatório, que estavam aguardando sua consulta, no dia 24 de novembro de 2023, período da manhã, com duração de 20 minutos. Por se tratar do mês de novembro, o foco da dinâmica foi referente a saúde do homem, com orientações aos usuários sobre a importância do autocuidado, necessidade de consulta médica periódica, alimentação regular, atividade física, entre outros. A dinâmica se deu de forma muito proveitosa, pois os usuários aproveitaram o espaço para esclarecer suas dúvidas, expressar seus anseios e otimizarem o seu tempo de espera para o atendimento ambulatorial. Conclusão: Infere-se que, tratar preventivamente a saúde do homem é um desafio para as unidades de saúde. Contudo, movimentos como o “Novembro Azul” auxiliam na superação de tal desafio. Vale destacar que palestras expositivas de orientação para a promoção à saúde são meios eficientes de intervenção para a comunidade. Palavras-chave: saúde do homem; intervenção educativa; câncer de próstata.
Atuação da enfermagem frente à Gangrena de Fournier: uma revisão integrativa
Authors: Gonçalves Silva Andressa , Valentim Ferreira Vinhais Lynne Hellen , Souza Reis Silênio , da Silva Lima Solange , Marçal da Silva Rulio Glecias
Published: September 2024

Objetivo: Apresentar as ações assistências e a produtividade científica no Brasil acerca dos cuidados de enfermagem frente à Gangrena de Fournier. Métodos: Trata-se de uma revisão integrativa da literatura, publicada entre os anos de 2018 e 2023, nas bases de dados PUBMED, Scopus, BVS, CAPES e Lilacs, a partir da pergunta norteadora elaborada pela estratégia PICO. Resultados: Um total de 9 artigos compôs a amostra após atender aos critérios de inclusão. Os principais achados nos estudos foram agrupados e formaram quatro categorias, sendo elas: perfil sociodemográfico e clínico dos pacientes com Gangrena de Fournier; tratamentos atuais para a Gangrena de Founier; conhecimento dos profissionais de Enfermagem sobre a Gangrena de Founier e assistência de enfermagem ao paciente com Grangrena de Founier. Conclusão: As pesquisas sinalizaram a necessidade de mais de publicações, principalmente de estudos primários, entretanto as evidências apontaram que a atuação da enfermagem tem sido fundamentada na sistematização da assistência de enfermagem e as intervenções permeiam, principalmente, a avaliação da lesão, a realização de curativos, a administração de medicamentos e na participação das novas terapias recomendadas como a terapia hiperbárica, a vácuo e a pressão negativa. Palavras-chave: gangrena fournier; ferimentos e lesões; cuidados de enfermagem.
Análise da mortalidade por câncer de colón e reto no Brasil (2012-2021)
Authors: Doná Nunes Maria Vitória , Lourenço de Almeida Caroline , Gonçalves da Silva Rosângela , Domingues Caldeirão Talita , Coelho Mendes de Brito Haddad Patrícia , da Silva Daniel Augusto
Published: September 2024

Objetivo: Analisar a mortalidade por câncer de cólon e reto no Brasil, nas regiões brasileiras e Unidades da Federação. Métodos: Trata-se de estudo retrospectivo, quantitativo, de dados secundários obtidos em março de 2023, por meio de consulta ao Departamento de Informática do Sistema Único de Saúde do Brasil. Os dados foram tabulados em planilhas, no software Excel da Microsoft. Realizou-se análise estatística descritiva, que proporcionou compreender as frequências absoluta e relativa, além dos cálculos para taxas de mortalidade, sendo consideradas populações de 100 mil habitantes. Resultados: Aumento gradual na taxa de óbitos por câncer de colón e reto no Brasil, em 2021 com 9,9/100.000. As mulheres apresentaram 99.683 (51,0%) dos casos de óbitos enquanto os homens registraram 95.622 (49,0%) óbitos. Na população com cor de pele branca verificou-se 124.940 (64,2%) óbitos, com maior incidência no Sul 34.125 (87,4%) e Sudeste 72.876 (68,3%). A população casada constitui 87.926 (44,8%), e a população idosa acima dos 60 anos com 140.831 (60,0%) óbitos. Os óbitos em hospitais foram 168.368 (86,7%). Conclusão: Dentre os aspectos analisados e descritos, há um aumento significativo e crescente nas taxas de mortalidade por câncer de colón, reto, junção retossigmoide, anus e canal anal no Brasil. Palavras-chave: neoplasias; neoplasias intestinais; neoplasias do colo; neoplasias retais; brasil.
Fatores associados a funcionalidade familiar em idosos hospitalizados
Authors: Vaz Liessa Aparecida , Nasser Figueiredo Valeria , Guimarães Raponi Maria Beatriz , Magnabosco Patrícia , Pena Porto Juliana
Published: September 2024

Objetivo: Analisar a funcionalidade familiar dos idosos hospitalizados e sua possível associação com a capacidade funcional. Métodos: Estudo observacional, com abordagem quantitativa, desenvolvido em um hospital de ensino brasileiro de grande porte. Como instrumentos de coleta dos dados utilizou-se questionário sociodemográfico, clínico e as Escalas de Katz, Lawton, Mini Exame do Estado Mental, depressão geriátrica e APGAR da família. Resultados: Participaram da pesquisa 233 idosos. A maioria deles eram do sexo masculino (147-63,1%), com idade entre 60 e 70 anos (127-54,7%), com hipertensão arterial sistêmica (155-66,5%), eles eram independentes para realizar ABVD (110-47,2%), com cognição preservada (156-67,0%), sinais de depressão (180-77,3%) e boa funcionalidade familiar (138-59,2%). A incidência da disfunção familiar foi maior para idosos que moravam sozinhos (27-61,4%), não praticavam nenhuma religião (22-59,5%) e que possuíam diabetes (42-58,3%). Conclusão: Há associação entre disfunção familiar e o fato de os idosos possuírem diabetes mellitus, morarem sozinhos e não praticarem religião. Palavras-chave: Enfermagem; família; hospitalização; saúde do idoso.
Optimizing the foam-mat drying of red dragon fruit: Effect of drying temperatures and foaming agentsOptimizing the foam-mat drying of red dragon fruit: Effect of drying temperatures and foaming agents
Authors: Thuy Nguyen Minh , Nhu Le Huynh , Giau Tran Ngoc , Hao Hong Van , Thanh Nguyen Van , Tai Ngo Van
Published: September 2024

Foam-mat drying is an economical method compared to other drying methods commonly used today, especially convenient for products with high viscosity and difficult to dry in food powder production. In this study, the red-flesh dragon fruit foam drying study was arranged according to the Box-Behnken design with 18 treatments and 6 center point replications. The input variables were egg albumin (EA) at varying concentrations of 5, 10 and 15%, and glycerol monostearate (GMS) at varying concentrations of 1, 3 and 5%. The drying process is arranged at temperatures of 50, 60 and 70oC. The dependent variables included in this study were betacyanin content (mg/100 g) and drying rate (g water/g dry matter/min). Response surface methodology was used to optimize the drying rate (g water/g dry matter/min) and betacyanin content (mg/100 g). Accordingly, the optimal conditions were found with concentrations of EA, GMS used and drying temperature of 10.43%, 2.97% and 63.21oC respectively. These conditions created foam-dried red flesh dragon fruit powder containing optimal content of betacyanin is 54.33 mg/100 g at the optimal drying rate of 1.78 g water/g dry matter/min. Foam-mat dried red dragon fruit powder has beautiful color, low moisture content (8%) with the water solubility index (41.05%), water absorption index (3.5%) and hygroscopicity (20.11%) were determined.
RP-HPLC-UV method validation for Ribavirin used in topical applications
Authors: Hamza Muhammad , Kanwal Qudsia , Raza Ahmad , Zehra Komal , Yasir Muhammad , Iqbal Dur e Najaf , Jamil Nuzhat , Afzal Muhammad Muddassar , Majeed Mudasir , Kamran Muhammad Zubair
Published: September 2024

In this research paper, accurate, cost effective and a straightforward reverse phase- High Performance Liquid Chromatography process was established and verified for the estimation of Ribavirin in topical dosage form. Chromatography separation technique was done on USP L17 (4.6mm×15cm) column possessing particles size of 5µm with liquid mobile phase consisting of sulfuric acid to a pH of 2.5±0.1 having column temperature 65±0.5ºC. Flow rate was kept 1mL per min. Estimation of ribavirin was done at 207nm with the help of UV-detector. Linearity was performed for Ribavirin and calibration curve was obtained which is linear for which is well within the limit. The method is developed & verified for accuracy, precision, linearity, range, specificity, and limit of detection (LOD), limit of quantization (LOQ), ruggedness & robustness. A simple, green, cost & time effective, robust and precise HPLC procedure for estimation of ribavirin was established. This procedure was then verified according to ICH guidelines Q2 (R1) Validation of Analytical methods. Ribavirin was determined accurately and precisely in topical dosage form. Overall this method was developed and performed for the determination of ribavirin amount in any dosage form within 2 minutes in a precise and accurate way.
Evaluation of antioxidant, cytoprotective and genoprotective potential of Syzygium aromaticum (L.) hydrolyzed extracts
Authors: Yasir Muhammad , Jamil Nuzhat , Ali Hafiz Muhammad Saad , Hussain Maria , Naveed Muhammad Akram , Ahmed Toheed , Bukhari Attaullah , Kanwal Qudsia , Iqbal Javed , Nusrat Madiha
Published: September 2024

Plants of medicinal values have been used to cure many diseases since ancient times. Various bioactive ingredients of such medicinal plants serve to hinder the progression of many infectious diseases. The current study was designed to evaluate the antioxidant, anti-haemolytic and genoprotective activities of a selected medicinal plant i.e. Syzygium aromaticum. Extraction with aqueous methanol in variable concentrations viz; 50%, 70% and 100 % to squeeze out the loosely bound phenolic compounds from plant cells; while strongly bound bioactives were recovered by hydrolyzed extraction proceeded by mineral acid, HCl (0.01N, 0.1N, 0.5N) and an alkali, NaOH (0.01N, 0.1N, 0.5N). Results demonstrated that methanol (100%) was able to extract highest number of phenolic compounds, as depicted by TPC assay (75.44±0.70 mg GAE/g extract) which were responsible for highest antioxidant potential by neutralizing DPPH free radicals (77.15±1.93%) and Fe3+ ion reducing capacity (72.55±2.49 mg AAE/g extract). Acidic hydrolyzed extraction gave even higher phenolic contents (93.12±0.72 mg GAE/g extract) while alkaline hydrolysis (84.22±0.24 mg GAE/g extract) was not quite satisfactory. Acidic hydrolyzed extract (0.1N) presented highest cytoprotective potential (95.15±1.44%) by preventing H2O2 induced oxidative damage to human red blood cells, and highest anti-mutation in selected bacterial strains (98.26±0.48%). Acidified hydrolyzed extract was then, subjected to HPLC phytochemical characterization that indicated the presence of twenty bioactive compounds belong to variable classes of phytochemicals. These results demonstrated that S. aromaticum could have potent medicinal and therapeutic applications.
Photocatalytic Potential of Green Synthesized ZnO Nanoparticles in Dye Removal Compared to TiO₂; a Performance Evaluation
Authors: Bibi Ayesha , Barkaat Samra , Ali Muhammad Sajid , Umar Shama , Asif Iqra , . Maryam , Shamim Hefza , Zuber Muhammad
Published: September 2024

The present study focuses on the photo catalytic degradation of Reactive Blue 13 dye using a green synthesis process for the preparation of zinc oxide (ZnO) nanoparticles. In contrast, titanium dioxide (TiO₂) is used as a comparative catalyst. The synthesis of zinc oxide nanoparticles (ZnO-ZNP) was carried out using a green approach employing the grapefruit peel extract and characterized by scanning electron microscopy SEM and zeta potential analyses. SEM analysis showed the spheres and smooth pellets of ZnO nanoparticles with an average size of 62 nm; at the same time, zeta potential (-11.9 mV) was shown to have good dispersion stability properties. The photo catalytic degradation of Reactive Blue 13 (RB-13) was performed under UV light, and different parameters such as pH, catalyst concentration and irradiation time were used to achieve the most effective dye removal. The study revealed that 0.06 g of ZnO nanoparticles exhibited an impressive photo catalytic activity, achieving a remarkable 98% dye degradation efficiency at pH =11 and after an irradiation time period for a few hours (120 minutes). In comparison, TiO₂ performed with a lower efficiency of 86% under the same conditions. These findings indicate the capability of ZnO nanoparticles in intense textile dye removal processes for wastewater treatment. The high degradation efficiency of Reactive Blue 13 in optimum conditions proves the potential of ZnO as a green and economical photo catalyst for environmental remediation, surpassing conventional TiO₂ due to slow dye decolorization. The outcomes of this can be very helpful in advanced nanomaterial exploration for sustainable wastewater treatment purposes.
𝗟𝗘𝗦 𝗡𝗢𝗡-𝗗𝗜𝗧𝗦 𝗗𝗘 𝗟𝗔 𝗡𝗢𝗨𝗩𝗘𝗟𝗟𝗘 𝗢𝗥𝗜𝗘𝗡𝗧𝗔𝗧𝗜𝗢𝗡 𝗗𝗜𝗣𝗟𝗢𝗠𝗔𝗧𝗜𝗤𝗨𝗘 𝗗𝗘 𝗟’𝗜𝗥𝗔𝗡. 𝗣𝗢𝗥𝗧𝗥𝗔𝗜𝗧 𝗗𝗘𝗦 𝗘𝗡𝗝𝗘𝗨𝗫 𝗔𝗖𝗧𝗨𝗘𝗟𝗦 𝗘𝗧 𝗣𝗘𝗥𝗦𝗣𝗘𝗖𝗧𝗜𝗩𝗘𝗦
Authors:   Université Pédagogique Nationale, Lukunga Felly
Published: September 2024

Devenir une puissance militaire est le rêve de chaque pays. La bombe atomique constitue dans la géopolitique actuelle, l’un des éléments qui attestent la maturité défensive d’un Etat. L’arme nucléaire n’apporte pas seulement du prestige, elle crée aussi de la dissuasion et autorise son propriétaire à lancer des frappes offensives qui pourraient annihiler tout ennemi. En plus d’éviter les migraines variées qui viennent avec la mise en place d’un programme nucléaire militaire, dont les plus notables sont les sanctions internationales, rester éloigné du club des puissances nucléaires donne à l’Iran une plus grande flexibilité pour fabriquer des armes conventionnelles. Il sied de noter que la volonté de se doter de l’arme nucléaire est, dans une certaine mesure, le résultat de la guerre contre l’Irak (1980-1988), qui a beaucoup marqué le nouveau régime iranien issu de la révolution islamique de 1979. La montée en puissance militaire d’Israël, son grand ennemi, avait motivé également Téhéran et ses alliés, la Syrie et la Libye, à se doter de l’arme nucléaire, à partir de 1985. Cette démarche iranienne se définit dans une portée géopolitique de se hisser dans la « cour des grands », celles des pays dotés de la puissance nucléaire, afin de peser davantage sur les scènes régionale et mondiale. Cet article n’aborde pas les aspects liés à la remise en cause de l’accord nucléaire iranien par l’Administration de Donald Trump. Nos analyses se penchent sur le revirement de la diplomatie iranienne sur cette question. Mots-clés : diplomatie, programme nucléaire, Iran.
Sosialisasi dan Pendampingan Pendaftaran Kartu Indonesia Pintar Kuliah (KIP-K) Bagi Siswa-Siswi Tidak Mampu di Kepulauan Sula Maluku Utara
Authors: Aji Saputra  , Mirda Prisma Wijayanto  , Andy Hermawan  , Ismi Musdalifah Darsan  , Roni Kurniawan  , Hutri Handayani Isra  , Krishna Aji  , Zandy Pratama Zain  , Sheila Kusumaningrum  , Rusandry Rusandry  , Sartika Putri Sailuddin  , Firmansyah Firmansyah  , Agatha Christy Situru  , Syahrial Maulana  , Iwan Abdy
Published: September 2024

Kartu Indonesia Pintar Kuliah (KIP-K) is a scholarship given by the government to high school graduates and equivalent who excel but have economic limitations to continue their studies at university level, both at state and private universities. The Indonesian government has issued the KIP-K since 2020 as a form of educational assistance. In North Maluku Province, especially on Sula Island, there is still minimal information regarding KIP-K. This service activity aims to share information regarding the benefits of higher education and how to obtain a KIP-K scholarship for students who have financial limitations. This community service is carried out at SMAN 1 Kepulauan Sula, MAN 1 Kepulauan Sula, SMAN 7 Kepulauan Sula, SMAN 9 Kepulauan Sula and SMAN 11 Kepulauan Sula. This activity was carried out in two stages, namely socialization and mentoring. The implementation of this activity went well, smoothly and was full of enthusiasm from the participants, especially students who wanted to continue their studies at university level. The final result of this socialization and mentoring is that the participants have succeeded in creating their own accounts, filling in data and registering for KIP-K.
HISTORICAL ASPECTS AND TRENDS IN THE DEVELOPMENT OF THE POLITICAL INITIATIVE «ONE BELT, ONE ROAD» IN KAZAKHSTAN
Authors: Abidenkyzy Ainur , Almabekova Assel
Published: September 2024

Annotation. The article examines the history of the emergence and current course of the Chinese initiative "One Belt, one Road". The main purpose of the article is the analysis of economic and cultural cooperation between Kazakhstan and China, the analysis of the results. The "One Belt, One Road" initiative, which has attracted great attention from the international community and received positive feedback from the relevant countries. The New Silk Road in the 21st century is a large trade network combining transport, energy and telecommunications, as well as an international initiative to promote trade relations between Asia, Africa, Europe and China.

The research on this topic uses complex theoretical research methods, methods of comparison, differentiation, generalization, systematization. In the course of the study, the concept of common development and mutual benefit can contribute to the development of infrastructure in countries along the route, promote the regional business environment and ensure a more even distribution of factors of production. This initiative will reduce the cost of cooperation between the countries through cooperation in the field of economic corridors, industrial parks, technological networks, communication technologies and tourism, strengthen the relevance and complementarity of the overall development of Eurasia and give a powerful impetus to economic prosperity, relieving global tensions.

The scientific novelty of the article lies in the fact that the Chinese initiative "One Belt, One Road" currently defines a new course of economic cooperation with Kazakhstan. The study will analyze that China and more than 60 countries such as Asia, Africa and Europe are focused on connecting new trade and transport corridors across vast expanses of land and sea, as well as strengthening monetary cooperation, cultural exchanges and regional policy coordination between countries.
Pricing in the medical sector: Theoretical foundations and practical aspects
Authors: Inozemtsev Serhiy
Published: September 2024

Pricing is one of the components of ensuring competitive conditions in the market: it has its own specificity in the healthcare market, which is characterized by various forms of operation of enterprises, access to goods and services. The purpose of the study was to investigate the methods and approaches to this process in Ukraine, taking into account the peculiarities of the country’s development related to the full-scale invasion of the Russian Federation. The methods used in the study were formal and legal (to form logical links between individual regulatory documents) and comparison (to assess the specifics of pricing in the medical sector in different countries). The study assessed the pricing process as such and described the factors that influence it in practice in general and in the medical sector. It was also concluded that understanding the role of this process for both the state and potential clients is important, as it affects economic stability, quality of medical services, social justice. Particular attention was paid to such approaches as “cost+markup” and “market-based”. Based on the models built in this paper, it was concluded that these approaches should be used in symbiosis (to focus on both market conditions and the company’s goals for forming a margin). Attention was also paid to the Value-Based Pricing approach: it was concluded that it is inherently different from the other two approaches, as it requires much more complex estimates, since it is based on the expected utility of the created product. The study also highlighted the problem of non-transparent pricing as one of the main ones that prevents the formation of effective market conditions. The results obtained in the study can be used both to formulate public policy and to create strategies for individual companies in the Ukrainian market of medical goods and services
ปัจจัยทำนายความคลาดเคลื่อนจากการสั่งใช้ยาผู้ป่วยนอก โรงพยาบาลพระจอมเกล้า จังหวัดเพชรบุรี
Authors: เพียรชนะ ชูเกียรติ
Published: September 2024

การวิจัยเชิงวิเคราะห์แบบศึกษาเปรียบเทียบย้อนหลังนี้มีวัตถุประสงค์เพื่อศึกษาปัจจัยที่มีสัมพันธ์กับการเกิดความคลาดเคลื่อนจากการสั่งใช้ยาผู้ป่วยนอก โรงพยาบาลพระจอมเกล้า จังหวัดเพชรบุรี และสร้างสมการทำนายการเกิดความคลาดเคลื่อนจากการสั่งใช้ยา ประชากรที่ศึกษาได้แก่ ใบสั่งยาผู้ป่วยนอกตั้งแต่วันที่ 1 ตุลาคม 2564 – 31 มีนาคม 2565 จำนวน 91,699 ฉบับ เก็บข้อมูลย้อนหลังโดยการสุ่มตัวอย่างใบสั่งยาจากฐานข้อมูลอิเล็กทรอนิกส์ของโรงพยาบาลฯ เป็นกลุ่มศึกษาและกลุ่มตัวอย่างจำนวน 188 และ 376 ใบสั่งยา ตามลำดับ วิเคราะห์ข้อมูลโดยใช้สถิติข้อมูลตัวแปรเดี่ยวและตัวแปรตามหลายตัวด้วยการวิเคราะห์การถดถอยโลจิสติคทวิที่ระดับนัยสำคัญ 0.05 ผลการศึกษาพบว่า ปัจจัยที่สัมพันธ์กับการเกิดความคลาดเคลื่อนจากการสั่งใช้ยาผู้ป่วยนอก ได้แก่ ค่าอัตราการกรองของไต (อีจีเอฟอาร์) ค่าระยะเวลาในการแข็งตัวของเลือด (ไอเอ็นอาร์) จำนวนรายการยาต่อใบสั่งยา การได้รับยากลุ่มเสี่ยงสูง และการได้รับยากลุ่มหัวใจและหลอดเลือด ปัจจัยที่สามารถทำนายโอกาสเกิดความคลาดเคลื่อนจากการสั่งใช้ยาผู้ป่วยนอก ได้แก่ ค่าอีจีเอฟอาร์น้อยกว่า 60 มิลลิลิตร/นาที/1.73 ตารางเมตร (ORadj = 2.625, 95% CI = 1.24 – 5.55) ค่าไอเอ็นอาร์ที่อยู่นอกช่วงปกติ (ORadj = 7.978, 95% CI = 2.69 – 23.67) และจำนวนรายการยาที่มากกว่า 7 รายการ/ใบสั่งยา (ORadj = 1.960, 95% CI = 1.23 – 3.13) และโอกาสเกิดความคลาดเคลื่อนจากการสั่งใช้ยา (p) เป็นดังสมการ p = 1/[1+e-log(odds)] โดยที่ Log (odds) =         -1.013 + 0.965 (eGRF <60) + 2.077 (INR นอกช่วงปกติ) + 0.673 (รายการยา > 7) ดังนั้น เภสัชกรผู้ทำหน้าที่วิเคราะห์คำสั่งใช้ยาเพื่อดักจับความคลาดเคลื่อนจากการสั่งใช้ยาในกระบวนการก่อนจ่ายยาผู้ป่วยนอก หากพบปัจจัยทำนายดังกล่าวข้างต้นปรากฏในฐานข้อมูล ควรให้ความสำคัญกับใบสั่งยานั้นเป็นพิเศษ เพื่อลดโอกาสเกิดความคลาดเคลื่อนที่จะไปถึงตัวผู้ป่วย ส่งผลให้ผู้ป่วยมีความปลอดภัยในการใช้ยามากขึ้น
การพัฒนาแอปพลิเคชันการบริหารคลังยาร่วมกับเทคโนโลยีความเป็นจริงเสริม
Authors: ภมรศิลปธรรม พีรยศ , พันตารักษ์ ฐิฏิการ
Published: September 2024

การบริหารจัดการคลังยา เป็นส่วนหนึ่งของระบบยาในโรงพยาบาลที่สำรองยาอย่างเหมาะสม ปลอดภัย และมีคุณภาพสูงพร้อมใช้ ทั้งนี้ในกระบวนการรับหรือตัดจ่ายสินค้า และรายงานสถานะสินค้า ยังพบการจัดการในรูปแบบกระดาษและไม่เป็นการทำงานแบบอิเล็กทรอนิกส์ การนำเทคโนโลยีความเป็นจริงเสริมร่วมกับแอปพลิเคชันบนมือถือช่วยแสดงผลข้อมูลสินค้าและสามารถรับและเบิกจ่าย จำนวนรายการยาได้เป็นทางเลือกเพื่อช่วยสนับสนุนการจัดการสินค้าในคลังยา งานวิจัยนี้เป็นการวิจัยเชิงพัฒนา มีวัตถุประสงค์เพื่อพัฒนาแอปพลิเคชันสำหรับจัดการสินค้าในคลังยาด้วยเทคโนโลยีความเป็นจริงเสริมแสดงผลรูปแบบ 2 มิติ ในระบบปฏิบัติการแอนดรอยด์ และประเมินผลการใช้งาน ผลการวิจัยพบว่า แอปพลิเคชันดังกล่าวทำงานตามความต้องการที่สอดคล้องกับกระบวนการทำงานเดิม คือ 1) รับสินค้าเข้าคลัง 2) ตัดจ่ายสินค้า และ 3) เรียกรายงานใบคุมสินค้า โดยใช้โปรแกรมที่เกี่ยวข้องพัฒนา คือ โปรแกรม Unity, Vuforia engine, Firestore สามารถบันทึกผลการรับสินค้า ตัดจ่ายสินค้า และเรียกดูใบคุมสินค้าได้ตามฟังก์ชันที่ออกแบบไว้ เมื่อนำไปทดสอบการปฏิบัติงานจริงสามารถนำไปใช้งานได้จริง สนับสนุนการจัดการคลังยาในการรับ-จ่ายสินค้า และตรวจสอบสินค้าตามระบบงานเดิมโดยเฉพาะการแสดงผลรูปแบบตัวยาที่ชัดเจน
กลไกภาวะเครียดที่เกิดจากออกซิเดชันในโรคไตเรื้อรัง
Authors: พงศ์นิมิตประเสริฐ นุชจิรา
Published: September 2024

โรคไตเรื้อรัง (Chronic kidney disease, CKD) เป็นปัญหาสุขภาพที่สำคัญซึ่งเกิดจากการทำลายของไตและท่อไต CKD มีลักษณะเฉพาะคือมีอัตราการกรองที่ไตลดลงและเกิดภาวะปัสสาวะมีโปรตีน (proteinuria) ตามมา งานวิจัยในช่วงที่ผ่านมาชี้ให้เห็นว่า ภาวะเครียดที่เกิดจากออกซิเดชัน (oxidative stress) มีบทบาทสำคัญในการทำให้เกิดพยาธิสภาพของโรคไตเรื้อรัง โดยในกระบวนการพัฒนาไปเป็นโรคไตเรื้อรังนั้นพบมีการสร้างอนุมูลอิสระทั้งชนิด reactive oxygen species (ROS) และ reactive nitrogen species (RNS) ที่มากเกินไปจนเกินความสามารถของระบบต้านอนุมูลอิสระของร่างกายที่จะสามารถกำจัดอนุมูลอิสระได้หมด ทำให้เกิดการทำลายโมเลกุลเป้าหมาย เช่น DNA โปรตีน และไขมัน ส่งผลให้เกิดการตายของเซลล์ มีหลักฐานแสดงให้เห็นว่า ภาวะเครียดที่เกิดจากออกซิเดชันนั้นสัมพันธ์กับการเกิด CKD และมีส่วนทำให้โรคไตแย่ลงผ่านกลไกหลายประการ ได้แก่ (1) การทำงานผิดปกติของไมโตคอนเดรียที่ทำให้เกิดการผลิต ROS เพิ่มขึ้น (2) การกระตุ้นของการทำงานของเอนไซม์ NADPH-Oxidase (NOX) isoforms ซึ่งเป็นแหล่งสำคัญของภาวะเครียดที่เกิดจากออกซิเดชันในไต (3) การแยกตัวของเอนไซม์ eNOS ซึ่งเป็นปัจจัยสำคัญที่ทำให้เกิดความเครียดจากออกซิเดชันและความเสียหายต่อไต (4) เอนไซม์ Myeloperoxidase (MPO) ซึ่งมีบทบาทในการพัฒนาและการแย่ลงของโรคไต (5) การทำงานของเอนไซม์ xanthine oxidase (XO) ที่เพิ่มขึ้นในผู้ป่วย CKD (6) การมีระดับเอนไซม์ superoxide dismutase-1 ที่สูงขึ้นในผู้ป่วยที่ได้รับการฟอกเลือด และ (7) การมีปัจจัยส่งเสริมการอักเสบใน CKD ที่ไปเพิ่มภาวะเครียดที่เกิดจากออกซิเดชันและรบกวนสมดุลเรด็อกซ์ ภาวะเครียดที่เกิดจากออกซิเดชันและการอักเสบนี้นำไปสู่การบาดเจ็บของเนื้อเยื่อ การแย่ลงของโรค และความรุนแรงของ CKD ในปัจจุบันมีการนำยาและสารต้านอนุมูลอิสระมาใช้เพื่อรับมือกับภาวะเครียดที่เกิดจากออกซิเดชันและเพื่อบรรเทาอาการทางคลินิก โดยมีวัตถุประสงค์เพื่อชะลอการแย่ลงของโรคและลดผลกระทบทางคลินิกที่เกิดจาก CKD
List apostolski «Solet annuere» papieża Honoriusza III (29 listopada 1223 roku). 800 lat od zatwierdzania «Reguły św. Franciszka»
Authors: Block Wiesław
Published: September 2024

W 2023 roku przypada osiemsetna rocznica podpisania przez Honoriusza III listu apostolskiego Solet annuere. Podpisując dokument 29 listopada, papież pozytywnie przyjął prośbę brata Franciszka i tym samym potwierdził tekst Reguły i Życia Braci Mniejszych. Nowa wspólnota, która pierwotnie nazywała się „pokutnikami z Asyżu”, otrzymała ważny dokument, a mianowicie prawne potwierdzenie przez Stolicę Apostolską swojej formy życia.
Bulla Solet annuere papieża Honoriusza III jest jakby ramą zawierającą tekst Reguły i życia Braci Mniejszych, znanej również jako Reguła zatwierdzona lub, bardziej popularnie, Reguła św. Franciszka. Ważne jest, aby zdać sobie sprawę, że poza tą bullą, tekst Reguły nie zachował się nigdzie indziej. Wszystkie późniejsze kopie zostały sporządzone na podstawie tego dokumentu.
Celem niniejszego artykułu jest analiza nie tyle tekstu Reguły, co listu apostolskiego (bulli) Solet annuere, w którym zapisano treść formy życia Zakonu Braci Mniejszych.
Pierwszy zakon franciszkański w diecezji kieleckiej (krakowsko–kieleckiej) w latach 1864–1918
Authors: Prejs Roland
Published: September 2024

Artykuł przedstawia sytuację Pierwszego Zakonu Franciszkańskiego na terenie diecezji kieleckiej po kasacie klasztorów w 1864 r. Od kasaty zostały zachowane klasztory franciszkanów–reformatów w Jędrzejowie, Pilicy, Pińczowie i Stopnicy; inne klasztory, bernardynów w Karczówce koło Kielc i franciszkanów konwentualnych w Nowym Korczynie, zostały skasowane przez carat w 1864 r. Władze carskie zakazały przyjmowania nowicjuszy, dlatego liczba zakonników w poszczególnych klasztorach szybko zaczęła się zmniejszać. W 1870 r. carat zniósł klasztor w Jędrzejowie, a zakonnicy zostali przesiedleni do Wysokiego Koła w diecezji sandomierskiej. Spora grupa zakonników, przede wszystkim franciszkanów–reformatów, ale także obserwantów, podjęła pracę w duszpasterstwie parafialnym, ostatecznie przechodząc do duchowieństwa diecezjalnego. Wybuchu I wojny światowej i odzyskania niepodległości przez Polskę doczekali: o. Dionizy Goc w Stopnicy i o. Apolinary Szlenk w Pilicy; wkrótce klasztory te zostały obsadzone przez zakonników przybyłych z dawnego zaboru austriackiego.
Krakowski klasztor franciszkanów w czasie niemieckiej okupacji [1939–1945] w świetle zakonnych dokumentów
Authors: Solarz Franciszek
Published: September 2024

Od 1237 r. w Krakowie trwa w sposób nieprzerwany klasztor franciszkanów. Rankiem 6 września 1939 r. Niemcy rozpoczęli 1961-dniową okupację Krakowa. Niniejszy artykuł ma na celu ukazanie życia i pracy klasztoru w tym okresie. Opisując jego życie, naciski władz okupacyjnych, zabieranie przez nie pomieszczeń klasztornych, rewizje i aresztowania, troskę klasztoru o zabezpieczenie i uchronienie rzeczy cennych i zabytkowych, autor ukazuje niezłomność postawy franciszkanów w tym trudnym okresie.
BENEFÍCIOS DO USO DA LASERTERAPIA NA CICATRIZAÇÃO DE LESÕES POR PRESSÃO (LPP) EM PACIENTES ACAMADOS
Authors: Pires Maria Rita Souza , Gomes Renan Lucas Freire
Published: September 2024

As lesões por pressão são feridas que surgem em áreas da pele submetidas à pressão contínua,  especialmente em pacientes acamados ou com mobilidade reduzida. Essas lesões ocorrem  principalmente sobre proeminências ósseas, como quadris, calcanhares e sacro, e resultam da  interrupção do fluxo sanguíneo, levando à isquemia e à necrose tecidual. Atualmente, a laserterapia  tem se destacado como uma novidade no tratamento das lesões por pressão, como uma abordagem  não invasiva que acelera a cicatrização e promove a regeneração tecidual. Este estudo teve como  objetivo descrever os benefícios da laserterapia na cicatrização de lesões por pressão de pacientes  acamados. O método utilizado para o alcance do objetivo foi a revisão de literatura, baseada na  pesquisa por obras nas bases de dados SCIELO e MEDLINE, na qual foram submetidas a leitura  íntegra e elaboração do texto de discussão. No total, foram encontradas oito obras que ressaltam a  utilização de laserterapia para a cicatrização de lesões por pressão de pacientes acamados. A  laserterapia se destacou como um tratamento promissor para pacientes acamados com lesões por  pressão, não apenas acelerando a cicatrização das lesões, mas também melhorando a qualidade de  vida desses pacientes ao aliviar a dor e prevenir a progressão das feridas. Utilizando feixes de luz de  baixa intensidade, a terapia estimula a microcirculação, reduz a inflamação e aumenta a produção de  colágeno, proporcionando uma recuperação mais rápida e melhor qualidade de vida para os pacientes.  Essa abordagem personalizada é essencial para otimizar os resultados clínicos e estéticos, oferecendo  uma alternativa segura e eficaz para a gestão dessas lesões complexas, promovendo a qualidade de  vida dos pacientes acamados.
Recent Development of Arbitration Law in Brazil
Authors: Claudio Finkelstein Claudio
Published: September 2024

Arbitration in Brazil has undergone a remarkable transformation, graduating from a tentative start to a robust and thriving practice. Like many jurisdictions with complex judicial systems, Brazil has found in commercial arbitration a valuable tool to foster economic growth and provide efficient dispute resolution for both domestic and international parties. Initially, when the Arbitration Act was enacted in 1996, it was met with skepticism. Many Brazilian scholars and legal practitioners questioned its constitutionality, as the concept of removing cases from the traditional judiciary's purview seemed far-fetched. The turning point came when Brazil's Supreme Court upheld the constitutionality of the Arbitration Act, providing a significant boost to its adoption and legitimacy. Since then, the country has witnessed rapid advancements in arbitration practices, making it an increasingly attractive venue for resolving commercial disputes. This development reflects a growing confidence among businesses and legal experts in the efficiency and effectiveness of arbitration as a complementary mechanism to the traditional court system. This article aims to delve into the evolving legal environment surrounding arbitration in Brazil. It will explore the dynamic trends that have emerged, such as the increasing sophistication of arbitration procedures, the establishment of dedicated arbitration centers, and the rising number of professionals specializing in this field. Additionally, the article will analyze how these developments have influenced Brazil's attractiveness as a hub for international arbitration, and the impact this has on the nation's legal and economic landscape. By examining these aspects, the article will provide a comprehensive overview of the current state and future potential of arbitration in Brazil.
Civil Liability of The Air Carrier for Errors of The Aircraft Crew in Jordanian Law
Authors: Abdullah Al-maamari Abdulwahab , Yousef Mohammad Al-Adwan Abed Alhameed
Published: September 2024

The aircraft crew bears significant responsibility as they operate the aircraft in the sky, carrying numerous duties and exercising various authorities to perform their tasks effectively. The aircraft crew is obligated to fulfill their commitments towards the air carrier. Current study addresses the issues surrounding the extent of the air carrier's liability for errors committed by the aircraft crew. These errors may be personal, technical, or administrative during flight. We used a comparative, descriptive, and analytical approach to achieve the objectives of the thesis and answer its questions, which focus on defining the obligations and authorities of the aircraft crew and determining the nature of the air carrier's responsibility for errors of the aircraft crew. The key finding of study is that the Jordanian legislator has largely held the air carrier responsible for damages resulting from errors committed by the aircraft crew. Both the air carrier and the aircraft crew share responsibility for these damages towards third parties based on solidarity and mutual assistance. It is suggested to amend the text of Article (42/C) to include detailed provisions specifying the extent of responsibility for each member of the aircraft crew, the responsibility of the aircraft commander, operator, and air carrier in the face of actions leading to harm.
Agrarian Sacrifice Ritual in the Film’s Narration
Authors: Seliverstov I. K.
Published: September 2024

This article is devoted to a structure of an agrarian sacrifice ritual in a film’s narration, basing on such films as “Earth” by A.P. Dovzhenko and “Ryazan women” by O.I. Preobrazhenskaya. During research main aspects of the ceremonial structure were characterized. It includes: participants of the ceremony, a presence of a deity, a purpose of the sacrifice, its motive and an object of sacrifice. It deals with a dramatical situation of “crisis of ceremony”, causing a struggle between “old” and “new” priesthood for the right to actualize a myth of the Earth.
Stylistic and Narrative Innovations in Norman McLaren’s Works
Authors: Sheremet F. I.
Published: September 2024

This article is an attempt to theoretically comprehend the legacy of the famous canadian animator Norman McLaren, who worked in the field of abstract animation for many years, from his student days in the 1930s to the late 1970s. Apart from a brief creative sketch, this article includes two main sections devoted to the genesis of image and plot in McLaren's works — both animation and ‘photographic’ ones. McLaren wanted to create entirely new film canon, based equally on abstract and realistic basics. Summarized, McLaren works are pivotal in the context of the evolution of avant-garde animation, both in the construction of imagery and in the rehabilitation of narrative, previously almost entirely excluded from the realm of absolute film. McLaren's many years of creative activity are evaluated as a unified ethical and aesthetic doctrine. Along the whole article various critical approaches to his work being observed and analyzed.
The Artistic and Pictorial Features of Presenting the World-Duality Motif in the Film Mr. Decorator
Authors: Dobrosmyslova V. I.
Published: September 2024

The article examines the artistic aspects of presenting the world duality as exemplified by the film ‘‘Mr. Decorator’’ (1988) directed by O. Teptsov. The subject of the study is the world-duality as both an artistic device and a special case of the universal duality motif in world mythology and literature. The principle of duality most accurately reflects the phenomena and processes of the surrounding world and makes it possible to expand the iconic aesthetic picture of a work of art.
Brecht's Dialectical Dramaturgy in the Film Loveless by A. Zvyagintsev
Authors: Nosikova E. V.
Published: September 2024

This article analyzes the creative method of A. Zvyagintsev in the painting “Dislike”. In the process of research, techniques similar to the practice of Bertold Brecht are revealed. The work demonstrated various techniques of Brecht's “alienation”, including the parabola, the “herald”, the destruction of the “fourth wall”, etc., which are used in his film by director A. Zvyagintsev. As a result of his work, the author of the article concludes about the special use of these techniques in the creative method of the director.
Взаимосвязь изобразительного решения и драматургии в фильмах С.И. Ростоцкого
Authors: Тютина Е. М.
Published: September 2024

В статье рассматривается связь реалистических и условных изобразительных приемов, примененных в фильмах кинорежиссера С.И. Ростоцкого, с драматургией: действием, характерами персонажей, жанровыми особенностями на примере фильмов «На семи ветрах» (1962), «Доживем до понедельника» (1968), «А зори здесь тихие…» (1972). Автор работы использует понятия реалистического и условного приемов для описания своеобразия творческого метода режиссера. В итоге статьи автор приходит к выводу, что стилистика фильмов С. Ростоцкого неповторима не только благодаря определенным смысловым и драматургическим особенностям, но и сочетанию двух видов изобразительных приемов.
COMMUNICATIVE COMPETENCE IN A GLOBAL HOSPITALITY WORKPLACE: ASSESSMENT OF ENGLISH LANGUAGE COMPETENCY OF BSHM GRADUATING STUDENTS
Authors: Manalastas Arriane Kris M.
Published: September 2024

This paper aimed to determine the 76 Bachelor of Science in Hospitality Management (BSHM) graduating students’ self- assessed English language communicative competence, their English language competency level and the factors that have contributed to their English competency using the Descriptive- Correlational Research Design and Thematic Analysis through a survey questionnaire, teacher- made test, and open- ended questionnaire. The result showed that the graduating students have evaluated themselves as competent in their overall competency in the English language, the students demonstrated a high level of communicative competence, and there is no significant association with their self-assessed competency and their actual competence in the English language because there might be factors other than self- perceived competency that were contributing to the level of English proficiency of students. In addition, affective factors such as anxiety, self- confidence, and motivation, cognitive factors such as semantic familiarity, and their growing and learning environment and prior linguistic knowledge and exposure had influenced the students’ English competency. It was suggested that a training program in English to develop the self- confidence and motivation and reduce the student’s anxiety in using English, promotion of communicative language teaching and creating of enabling environment for the usage of the language in classes should be conducted, and an actual speaking and writing skills test should be administered.
Management of Tetanus Patients in the Intensive Care Unit : A Case Report
Authors: Hanafia Mochamad Fauzi , Adiyanto Bowo
Published: September 2024

We report a case of a 41-year-old male patient with a history of a nail puncture wound who presented to the Emergency Department (ED) with complaints of generalized body stiffness. The patient experienced worsening stiffness, particularly in the neck, jaw, back, and abdomen. He was diagnosed with tetanus and received initial treatment with human tetanus immunoglobulin (HTIG) and antibiotics. The patient was admitted to the intensive care unit (ICU) due to the risk of recurrent seizures and airway obstruction. During the treatment, he developed several complications, including pneumonia and hematemesis. Supportive care was provided, including adequate nutrition, prevention of pressure sores, and physiotherapy. The patient showed improvement after the administration of magnesium sulfate (MgSO4) to control spasms and autonomic dysfunction. He was successfully weaned off the ventilator and discharged after 40 days of intensive care.
The Analysis Study of Comparison of Effectiveness and Safety of Inhalers in Mild-to Moderate Asthma in Adults: A Comprehensive Systematic Review
Authors: Harve Akbar Fathoni
Published: September 2024

Background: Asthma, a prevalent and potentially debilitating chronic disease, is traditionally managed using reliever medications such as short-acting β2-agonists (SABA) or low-dose inhaled corticosteroids (ICS). Recent evidence, however, indicates that a combination of as-needed ICS and a rapid-acting long-acting β2-agonist (LABA) provides superior outcomes compared to SABA alone. Furthermore, this combination therapy is at least as effective as regular ICS in mitigating the risk of exacerbations. This emerging evidence highlights a significant shift in treatment strategies for mild asthma, underscoring the potential for enhanced management and improved patient outcomes with the new therapeutic approach. Methods: Following PRISMA 2020 guidelines, this systematic review focused exclusively on full-text articles published in English between 2014 and 2024. Result: The study conducted a comprehensive review of over 400 publications sourced from reputable databases, including ScienceDirect, SagePub, and PubMed. Folowing an initial screening, eight publications were identified as warranting more in-depth analysis. Conclusion: The study found that as-needed ICS/LABA is effective in preventing exacerbations in mild-to-moderate asthma patients, but less effective than regular ICS in improving FEV1 and ACQ scores. Combining ICS/LABA with SMART regimen was highest for severe exacerbations prevention.
High-Accuracy Forex Trading Prediction Model Using Machine Learning Algorithms
Authors: Onuiri Ernest E. , Chikezie Tochukwu F. , Obata Ifeoma E. Z. , Amanze Ruth C.
Published: September 2024

The foreign exchange (Forex) market, the largest financial market globally, involves the simultaneous buying and selling of currency pairs such as the United States Dollar (USD) and the Japanese Yen (JPY). Due to the high leverage and volatility inherent in Forex trading, retail investors and traders face significant financial risks. To mitigate this, a predictive model was developed using supervised machine learning to improve trading outcomes. A dataset comprising EUR/USD currency pair data from MetaTrader5, covering a period of 7 years (2015–2022), was streamlined to 5 years (2017–2022) for relevance. The dataset contained 13 features and 1,029 records, which underwent data cleaning and processing. Feature selection was performed using the Boruta package in R, and various machine learning algorithms were employed for model training and testing. The model’s accuracy was evaluated using the ROC curve and the Kappa statistic. The inclusion of the Simple Moving Average indicator improved forecast accuracy. Among the algorithms tested, the Generalized Linear Model (Logistic Model) performed best, achieving an accuracy of 86.28%, a specificity of 87.42%, a sensitivity of 86.5%, and an AUC (ROC) score of 86.97%. This predictive model has the potential to optimize profits, particularly in the context of binary options trading within the Forex market.
APLIKASI MASHLAHAT TRANSAKSI EKONOMI SYARIAH KONTEMPORER PADA MADRASAH ALIYAH JIDRIS SALAM PERSPEKTIF LEGISLASI
Authors: Ratno Dedi
Published: September 2024

Artikel ini menjelaskan implementasi maslahat mursalah sebagai alternatif sumber hukumIslam terkait praktik – praktik transaksi di era modern yang semakin flesksibel sehingga dapatdipertanggung jawabkan secara syariah dan dapat menjawab tantangan zaman. Penelitian inimenggunakan metode kualitatif dan merupakan penelitian perpustakaan. Data dokumentasi yangdiperoleh dari sumber primer dan sekunder kemudian direduksi, diverifikasi dan disajikan. Hasilpenelitian ini adalah : Perspektif madzhab- madzhab fikih, pro kontra pada teori maslahah danperbandingannya dengan qiyas, yang ternyata hanya berkutat dalam ranah istilah kaimat saja, karenapada prakteknya semua madzhab menggunakan maslahah mursalah. Berbagai bentuk perkembanganekonomi Islam, baik kelembagaan maupun produk, menunjukkan bahwa peran maslahah mursalahsangat signifikan. Seperti trend semakin maraknya perbankan syariah, munculnya kartu kredit syariahyang memfasilitasi berbagai transaksi, pembaruan dalam transaksi mudharabah seperti kewajibanjaminan dan bagi hasil sebagai metode bagi hasil. Dengan pesatnya perkembangan ekonomi syariah,penggunaan maslahah mursalah akan semakin dominan dan krusial sehingga syariat Islam dapatberadaptasi disetiap zaman dan waktu
INTEGRASI PENDIDIKAN AGAMA ISLAM DAN SAINS DALAM MENINGKATKAN MUTU PENDIDIKAN SERTA MEMBANGUN BRAND IMAGE ( Studi Kasus di MA Persis Sindangkasih Ciamis )
Authors: Luthfi Rifyal
Published: September 2024

Penelitian ini bertujuan untuk menganalisis dan mendokumentasikan implementasi integrasi pendidikan agama Islam dan sains dalam meningkatkan mutu pendidikan serta membangun brand image di MA Persis Sindangkasih Ciamis. Penelitian ini menggunakan pendekatan kualitatif dengan studi kasus sebagai metode penelitian. Data dikumpulkan melalui observasi partisipatif, wawancara mendalam, dan analisis dokumen terkait.Hasil penelitian menunjukkan bahwa MA Persis Sindangkasih Ciamis telah berhasil menerapkan integrasi pendidikan agama Islam dan sains dengan baik. Integrasi ini terlihat dalam perencanaan pembelajaran, pengembangan kurikulum, dan metode pengajaran yang digunakan. Pendekatan ini menciptakan lingkungan pendidikan yang holistik dan membantu siswa mengembangkan pemahaman yang komprehensif tentang agama Islam dan sains. Penelitian ini juga mengidentifikasi beberapa tantangan dalam mengimplementasikan integrasi pendidikan agama Islam dan sains, termasuk kurangnya sumber daya, tantangan dalam mengintegrasikan kurikulum, dan kebutuhan akan pelatihan dan pembinaan bagi para guru. Namun, melalui kolaborasi antara pihak sekolah, guru, siswa, dan stakeholder terkait, MA Persis Sindangkasih Ciamis berhasil mengatasi tantangan tersebut. Kesimpulannya, integrasi pendidikan agama Islam dan sains di MA Persis Sindangkasih Ciamis memberikan manfaat yang signifikan dalam meningkatkan mutu pendidikan dan membangun brand image institusi. Studi ini memberikan pemahaman yang lebih mendalam tentang implementasi praktis integrasi tersebut dan memberikan kontribusi pada pengembangan pendidikan di Indonesia. Rekomendasi disampaikan untuk institusi pendidikan lainnya yang ingin menerapkan integrasi serupa, termasuk perlunya dukungan sumber daya yang memadai dan pelatihan bagi para guru.