bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure S1 from Radiation Sensitivity in a Preclinical Mouse Model of Medulloblastoma Relies on the Function of the Intrinsic Apoptotic Pathway
Authors: Crowther Andrew J. , Ocasio Jennifer K. , Fang Fang , Meidinger Jessica , Wu Jaclyn , Deal Allison M. , Chang Sha X. , Yuan Hong , Schmid Ralf , Davis Ian , Gershon Timothy R.
Published: April 2023

Additional histological studies.
Supplementary Figure S6 from Targeting a Plk1-Controlled Polarity Checkpoint in Therapy-Resistant Glioblastoma-Propagating Cells
Authors: Lerner Robin G. , Grossauer Stefan , Kadkhodaei Banafsheh , Meyers Ian , Sidorov Maxim , Koeck Katharina , Hashizume Rintaro , Ozawa Tomoko , Phillips Joanna J. , Berger Mitchel S. , Nicolaides Theodore , James C. David , Petritsch Claudia K.
Published: April 2023

GBM cell viability and tumor growth after combined PLK1 and MAPK inhibition compared with MAPK inhibition alone.
Supplementary Figure S5 from Targeting a Plk1-Controlled Polarity Checkpoint in Therapy-Resistant Glioblastoma-Propagating Cells
Authors: Lerner Robin G. , Grossauer Stefan , Kadkhodaei Banafsheh , Meyers Ian , Sidorov Maxim , Koeck Katharina , Hashizume Rintaro , Ozawa Tomoko , Phillips Joanna J. , Berger Mitchel S. , Nicolaides Theodore , James C. David , Petritsch Claudia K.
Published: April 2023

Sensitivity of CD133+ subpopulations to MAPK pathway inhibition.
Supplementary Figure S3 from Bortezomib Improves Adoptive T-cell Therapy by Sensitizing Cancer Cells to FasL Cytotoxicity
Authors: Shanker Anil , Pellom Samuel T. , Dudimah Duafalia F. , Thounaojam Menaka C. , de Kluyver Rachel L. , Brooks Alan D. , Yagita Hideo , McVicar Daniel W. , Murphy William J. , Longo Dan L. , Sayers Thomas J.
Published: April 2023

Calreticulin expression on bortezomib-treated tumor cells.
Supplementary Figure S4 from Targeting a Plk1-Controlled Polarity Checkpoint in Therapy-Resistant Glioblastoma-Propagating Cells
Authors: Lerner Robin G. , Grossauer Stefan , Kadkhodaei Banafsheh , Meyers Ian , Sidorov Maxim , Koeck Katharina , Hashizume Rintaro , Ozawa Tomoko , Phillips Joanna J. , Berger Mitchel S. , Nicolaides Theodore , James C. David , Petritsch Claudia K.
Published: April 2023

PLK1 control of mitotic entry and cell polarity in CD133+ cells.
Supplementary Figure S1 from Targeting a Plk1-Controlled Polarity Checkpoint in Therapy-Resistant Glioblastoma-Propagating Cells
Authors: Lerner Robin G. , Grossauer Stefan , Kadkhodaei Banafsheh , Meyers Ian , Sidorov Maxim , Koeck Katharina , Hashizume Rintaro , Ozawa Tomoko , Phillips Joanna J. , Berger Mitchel S. , Nicolaides Theodore , James C. David , Petritsch Claudia K.
Published: April 2023

Proliferation rates and compartment overlap of CD133+ and NG2+ GBMs.
Supplementary Figure Legends from Targeting a Plk1-Controlled Polarity Checkpoint in Therapy-Resistant Glioblastoma-Propagating Cells
Authors: Lerner Robin G. , Grossauer Stefan , Kadkhodaei Banafsheh , Meyers Ian , Sidorov Maxim , Koeck Katharina , Hashizume Rintaro , Ozawa Tomoko , Phillips Joanna J. , Berger Mitchel S. , Nicolaides Theodore , James C. David , Petritsch Claudia K.
Published: April 2023

Legends for Supplementary Figures S1-S7.
Supplementary Table S1 from MicroRNA-22 Suppresses DNA Repair and Promotes Genomic Instability through Targeting of MDC1
Authors: Lee Jung-Hee , Park Seon-Joo , Jeong Seo-Yeon , Kim Min-Ji , Jun Semo , Lee Hyun-Seo , Chang In-Youb , Lim Sung-Chul , Yoon Sang Pil , Yong Jeongsik , You Ho Jin
Published: April 2023

Supplementary Table S1. miRNA predicted to bind the 3`UTR of the MDC1 gene by at least 4 algorithms.
Supplementary Figures S1-S10 from MicroRNA-22 Suppresses DNA Repair and Promotes Genomic Instability through Targeting of MDC1
Authors: Lee Jung-Hee , Park Seon-Joo , Jeong Seo-Yeon , Kim Min-Ji , Jun Semo , Lee Hyun-Seo , Chang In-Youb , Lim Sung-Chul , Yoon Sang Pil , Yong Jeongsik , You Ho Jin
Published: April 2023

Supplementary Figures S1-S10. Supplementary Figure S1. miR-22 negatively regulates MDC1 expression. Supplementary Figure S2. The effect of miR-22 on the IR-induced nuclear foci of MDC1, 53BP1, and BRCA1 in U2OS cells. Supplementary Figure S3. Reintroduction of MDC1 rescues miR-22-mediated inhibition of DSB repair in U2OS cells. Supplementary Figure S4. Genome-wide DNA copy number variation in the miR-22-overexpressing GM00637 cells. Supplementary Figure S5. miR-22 levels frequently increased in prostate cancer tissues with high pAkt and low MDC1 expression. Supplementary Figure S6. Busufan-induced premature senescence leads to suppression of MDC1 expression. Supplementary Figure S7. Impairment of IR-induced MDC1 foci formation in senescent cells. Supplementary Figure S8. Decline of DNA double-strand break (DSB) repair efficiency in senescent cells. Supplementary Figure S9. Rescue of MDC1 expression in senescent MRC-5 and IMR-90 cells by transfection of miR-22-insensitive MDC1. Supplementary Figure S10. Overexpression of miR-22 induces senescent-like phenotypes in human cancer cells.
Supplemental Materials and Methods and Legends from MicroRNA-22 Suppresses DNA Repair and Promotes Genomic Instability through Targeting of MDC1
Authors: Lee Jung-Hee , Park Seon-Joo , Jeong Seo-Yeon , Kim Min-Ji , Jun Semo , Lee Hyun-Seo , Chang In-Youb , Lim Sung-Chul , Yoon Sang Pil , Yong Jeongsik , You Ho Jin
Published: April 2023

Supplemental materials and methods and legends for all supplemental figures.
Supplemental Figure 2 from Membrane IL1α Inhibits the Development of Hepatocellular Carcinoma via Promoting T- and NK-cell Activation
Authors: Lin Dandan , Lei Lei , Liu Yonghao , Zhang Yinsheng , Hu Bo , Bao Guangming , Song Yuan , Jin Ziqi , Liu Chunliang , Mei Yu , Sandikin Dedy , Wu Yan , Zhao Lixiang , Yu Xiao , Liu Haiyan
Published: April 2023

Supplemental Figure 2 IL-1α expression in human HCC tumor and the adjacent tissues.
Supplementary Table S5 from CLK2 Is an Oncogenic Kinase and Splicing Regulator in Breast Cancer
Authors: Yoshida Taku , Kim Jee Hyun , Carver Kristopher , Su Ying , Weremowicz Stanislawa , Mulvey Laura , Yamamoto Shoji , Brennan Cameron , Mei Shenglin , Long Henry , Yao Jun , Polyak Kornelia
Published: April 2023

Supplementary Table S5. Pathway map enrichment of genes upregulated after expression of shCLK2 in MCF7 cells.
Supplementary Table S4 from CLK2 Is an Oncogenic Kinase and Splicing Regulator in Breast Cancer
Authors: Yoshida Taku , Kim Jee Hyun , Carver Kristopher , Su Ying , Weremowicz Stanislawa , Mulvey Laura , Yamamoto Shoji , Brennan Cameron , Mei Shenglin , Long Henry , Yao Jun , Polyak Kornelia
Published: April 2023

Supplementary Table S4. List of genes differentially expressed following shCLK2 expression in MCF7 cells.
Supplementary Table S2 from CLK2 Is an Oncogenic Kinase and Splicing Regulator in Breast Cancer
Authors: Yoshida Taku , Kim Jee Hyun , Carver Kristopher , Su Ying , Weremowicz Stanislawa , Mulvey Laura , Yamamoto Shoji , Brennan Cameron , Mei Shenglin , Long Henry , Yao Jun , Polyak Kornelia
Published: April 2023

Supplementary Table S2. Copy number gain and expression of selected kinases in primary breast tumors based on qPCR.
Supplemental Figure S3 from Generation of a Mouse Model of Atypical Teratoid/Rhabdoid Tumor of the Central Nervous System through Combined Deletion of Snf5 and p53
Authors: Ng Jessica M.Y. , Martinez Daniel , Marsh Eric D. , Zhang Zhe , Rappaport Eric , Santi Mariarita , Curran Tom
Published: April 2023

NG2 expression in Snf5F/F p53L/L GFAP-Cre mutant brain tissue.
Table S6 from Whole-Exome Sequencing Reveals Frequent Genetic Alterations in BAP1, NF2, CDKN2A, and CUL1 in Malignant Pleural Mesothelioma
Authors: Guo Guangwu , Chmielecki Juliann , Goparaju Chandra , Heguy Adriana , Dolgalev Igor , Carbone Michele , Seepo Sara , Meyerson Matthew , Pass Harvey I.
Published: April 2023

Table S6. List of significant focal copy number alterations in the 22 MPMs
Supplementary methods and supplementary figure Legends from Disseminated Tumor Cells Persist in the Bone Marrow of Breast Cancer Patients through Sustained Activation of the Unfolded Protein Response
Authors: Bartkowiak Kai , Kwiatkowski Marcel , Buck Friedrich , Gorges Tobias M. , Nilse Lars , Assmann Volker , Andreas Antje , Müller Volkmar , Wikman Harriet , Riethdorf Sabine , Schlüter Hartmut , Pantel Klaus
Published: April 2023

Supplementary methods and supplementary figure Legends
Supplemental Table S2 from Akt–Girdin Signaling in Cancer-Associated Fibroblasts Contributes to Tumor Progression
Authors: Yamamura Yumiko , Asai Naoya , Enomoto Atsushi , Kato Takuya , Mii Shinji , Kondo Yuji , Ushida Kaori , Niimi Kaoru , Tsunoda Nobuyuki , Nagino Masato , Ichihara Shu , Furukawa Koichi , Maeda Kengo , Murohara Toyoaki , Takahashi Masahide
Published: April 2023

Correlations between clinicopathological features and Girdin phosphorylation in CAF.
Supplemental Figure 2 from Glioblastomas Require Integrin αvβ3/PAK4 Signaling to Escape Senescence
Authors: Franovic Aleksandra , Elliott Kathryn C. , Seguin Laetitia , Camargo M. Fernanda , Weis Sara M. , Cheresh David A.
Published: April 2023

Cell cycle analysis
Supplemental Figure S1 from Guidance Molecule SEMA3A Restricts Tumor Growth by Differentially Regulating the Proliferation of Tumor-Associated Macrophages
Authors: Wallerius Majken , Wallmann Tatjana , Bartish Margarita , Östling Jeanette , Mezheyeuski Artur , Tobin Nicholas P. , Nygren Emma , Pangigadde Pradeepa , Pellegrini Paola , Squadrito Mario Leonardo , Pontén Fredrik , Hartman Johan , Bergh Jonas , De Milito Angelo , De Palma Michele , Östman Arne , Andersson John , Rolny Charlotte
Published: April 2023

SEMA3A DOES NOT AFFECT TUMOR CELL METABOLISM.
Supplementary Figure S1 from Exploring the Biomechanical Properties of Brain Malignancies and Their Pathologic Determinants In Vivo with Magnetic Resonance Elastography
Authors: Jamin Yann , Boult Jessica K.R. , Li Jin , Popov Sergey , Garteiser Philippe , Ulloa Jose L. , Cummings Craig , Box Gary , Eccles Suzanne A. , Jones Chris , Waterton John C. , Bamber Jeffrey C. , Sinkus Ralph , Robinson Simon P.
Published: April 2023

Supplementary Figure S1. Schematic of the MR elastography platform used in this study.
supplementary data figure legends from Citrullinated Vimentin Presented on MHC-II in Tumor Cells Is a Target for CD4+ T-Cell–Mediated Antitumor Immunity
Authors: Brentville Victoria A. , Metheringham Rachael L. , Gunn Barbara , Symonds Peter , Daniels Ian , Gijon Mohamed , Cook Katherine , Xue Wei , Durrant Lindy G.
Published: April 2023

figure legends
Supplementary Table S1 from Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin–GUCY2C Paracrine Signaling Axis
Authors: Lin Jieru E. , Colon-Gonzalez Francheska , Blomain Erik , Kim Gilbert W. , Aing Amanda , Stoecker Brian , Rock Justin , Snook Adam E. , Zhan Tingting , Hyslop Terry M. , Tomczak Michal , Blumberg Richard S. , Waldman Scott A.
Published: April 2023

Mouse diet calorie and nutrient content.
Supplementary Table S2 from Candidate Antimetastasis Drugs Suppress the Metastatic Capacity of Breast Cancer Cells by Reducing Membrane Fluidity
Authors: Zhao Weina , Prijic Sara , Urban Bettina C. , Tisza Michael J. , Zuo Yan , Li Lin , Tan Zhi , Chen Xiaoling , Mani Sendurai A. , Chang Jeffrey T.
Published: April 2023

Connectivity Map results.
Supplementary Figure S3 from Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin–GUCY2C Paracrine Signaling Axis
Authors: Lin Jieru E. , Colon-Gonzalez Francheska , Blomain Erik , Kim Gilbert W. , Aing Amanda , Stoecker Brian , Rock Justin , Snook Adam E. , Zhan Tingting , Hyslop Terry M. , Tomczak Michal , Blumberg Richard S. , Waldman Scott A.
Published: April 2023

Daily calorie intake and body weights in mice on lean, high carbohydrate (HC), or high fat (HF) diets.
Supplementary Figure S2 from Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin–GUCY2C Paracrine Signaling Axis
Authors: Lin Jieru E. , Colon-Gonzalez Francheska , Blomain Erik , Kim Gilbert W. , Aing Amanda , Stoecker Brian , Rock Justin , Snook Adam E. , Zhan Tingting , Hyslop Terry M. , Tomczak Michal , Blumberg Richard S. , Waldman Scott A.
Published: April 2023

Relative GUCY2C expression in proximal (PC) and distal (DC) colons of mice on lean or high fat (HF) diets.
Supplementary Figure S2 from Candidate Antimetastasis Drugs Suppress the Metastatic Capacity of Breast Cancer Cells by Reducing Membrane Fluidity
Authors: Zhao Weina , Prijic Sara , Urban Bettina C. , Tisza Michael J. , Zuo Yan , Li Lin , Tan Zhi , Chen Xiaoling , Mani Sendurai A. , Chang Jeffrey T.
Published: April 2023

Drug treatment alters metastatic capacity.
Supplementary Figures S1-S6 from Interactions between Adipocytes and Breast Cancer Cells Stimulate Cytokine Production and Drive Src/Sox2/miR-302b–Mediated Malignant Progression
Authors: Picon-Ruiz Manuel , Pan Chendong , Drews-Elger Katherine , Jang Kibeom , Besser Alexandra H. , Zhao Dekuang , Morata-Tarifa Cynthia , Kim Minsoon , Ince Tan A. , Azzam Diana J. , Wander Seth A. , Wang Bin , Ergonul Burcu , Datar Ram H. , Cote Richard J. , Howard Guy A. , El-Ashry Dorraya , Torné-Poyatos Pablo , Marchal Juan A. , Slingerland Joyce M.
Published: April 2023

hASC characterization (S1); Co-culture of immature adipocytes with mammary epithelial cells increases pro-inflammatory cytokine expression (S2); Immature adipocyte or cytokine exposure increases abundance of sphere and colony forming cells without changing global cell proliferation (S3); Immature adipocyte or cytokine exposure increases matrigel invasion in vitro and tumor formation, vasculogenesis and metastasis in vivo (S4); Src mediates cytokine effects via ES-TF upregulation affecting soft agar colony growth but not cell cycle progression (S5); Cytokine-mediated increase in sphere formation is Sox2-dependent and miR302b upregulation drives further c-MYC and SOX2 gene expression (S6).
Supplementary Methods and References from H3K27 Demethylase JMJD3 Employs the NF-κB and BMP Signaling Pathways to Modulate the Tumor Microenvironment and Promote Melanoma Progression and Metastasis
Authors: Park Woo-Yong , Hong Beom-Jin , Lee Jungsul , Choi Chulhee , Kim Mi-Young
Published: April 2023

Additional information on reagents and experimental procedures. Also includes Supplementary References.
Supplementary Figure S5 from ΔNp63α Silences a miRNA Program to Aberrantly Initiate a Wound-Healing Program That Promotes TGFβ-Induced Metastasis
Authors: Rodriguez Calleja Lidia , Jacques Camille , Lamoureux François , Baud'huin Marc , Tellez Gabriel Marta , Quillard Thibaut , Sahay Debashish , Perrot Pierre , Amiaud Jerome , Charrier Celine , Brion Regis , Lecanda Fernando , Verrecchia Franck , Heymann Dominique , Ellisen Leif W. , Ory Benjamin
Published: April 2023

p63 induces TGFÎ²-mediated metastasis in vivo.
Supplementary Figure S3 from H3K27 Demethylase JMJD3 Employs the NF-κB and BMP Signaling Pathways to Modulate the Tumor Microenvironment and Promote Melanoma Progression and Metastasis
Authors: Park Woo-Yong , Hong Beom-Jin , Lee Jungsul , Choi Chulhee , Kim Mi-Young
Published: April 2023

JMJD3 upregulates CCL2 and TFPI2 by activating the BMP pathway.
Supplementary Dataset 1 from H3K27 Demethylase JMJD3 Employs the NF-κB and BMP Signaling Pathways to Modulate the Tumor Microenvironment and Promote Melanoma Progression and Metastasis
Authors: Park Woo-Yong , Hong Beom-Jin , Lee Jungsul , Choi Chulhee , Kim Mi-Young
Published: April 2023

GSM numbers of each sample used in clinical sample analysis shown in Fig. 1D and 6G
Supplementary Figure S2 from ΔNp63α Silences a miRNA Program to Aberrantly Initiate a Wound-Healing Program That Promotes TGFβ-Induced Metastasis
Authors: Rodriguez Calleja Lidia , Jacques Camille , Lamoureux François , Baud'huin Marc , Tellez Gabriel Marta , Quillard Thibaut , Sahay Debashish , Perrot Pierre , Amiaud Jerome , Charrier Celine , Brion Regis , Lecanda Fernando , Verrecchia Franck , Heymann Dominique , Ellisen Leif W. , Ory Benjamin
Published: April 2023

miR-527 and miR-665 repress Smad4 and TÎ²RII, respectively.
Supplementary Figure S2 from CRLX101, a Nanoparticle–Drug Conjugate Containing Camptothecin, Improves Rectal Cancer Chemoradiotherapy by Inhibiting DNA Repair and HIF1α
Authors: Tian Xi , Nguyen Minh , Foote Henry P. , Caster Joseph M. , Roche Kyle C. , Peters Christian G. , Wu Pauline , Jayaraman Lata , Garmey Edward G. , Tepper Joel E. , Eliasof Scott , Wang Andrew Z.
Published: April 2023

Evaluation of skin toxicity following drug with radiation (XRT) treatment. (A) Representative images and (B) quantification of skin toxicities observed in animals 49 days following treatment with PBS (Control), CPT, or CRLX101 with radiation.
Supplementary Figure Legends from ΔNp63α Silences a miRNA Program to Aberrantly Initiate a Wound-Healing Program That Promotes TGFβ-Induced Metastasis
Authors: Rodriguez Calleja Lidia , Jacques Camille , Lamoureux François , Baud'huin Marc , Tellez Gabriel Marta , Quillard Thibaut , Sahay Debashish , Perrot Pierre , Amiaud Jerome , Charrier Celine , Brion Regis , Lecanda Fernando , Verrecchia Franck , Heymann Dominique , Ellisen Leif W. , Ory Benjamin
Published: April 2023

Legend for Supplementary Figures S1-S6
Supplementary Materials and Methods from MFG-E8 Drives Melanoma Growth by Stimulating Mesenchymal Stromal Cell–Induced Angiogenesis and M2 Polarization of Tumor-Associated Macrophages
Authors: Yamada Kazuya , Uchiyama Akihiko , Uehara Akihito , Perera Buddhini , Ogino Sachiko , Yokoyama Yoko , Takeuchi Yuko , Udey Mark C. , Ishikawa Osamu , Motegi Sei-ichiro
Published: April 2023

This file contains Supplementary Materials and Methods
Table S3 from Comparative Cistromics Reveals Genomic Cross-talk between FOXA1 and ERα in Tamoxifen-Associated Endometrial Carcinomas
Authors: Droog Marjolein , Nevedomskaya Ekaterina , Kim Yongsoo , Severson Tesa , Flach Koen D. , Opdam Mark , Schuurman Karianne , Gradowska Patrycja , Hauptmann Michael , Dackus Gwen , Hollema Harry , Mourits Marian J. , Nederlof Petra , van Boven Hester , Linn Sabine C. , Wessels Lodewyk , van Leeuwen Flora E. , Zwart Wilbert
Published: April 2023

Primer sequences corresponding with supplemental figure S2, to validate ChIP-seq on qPCR.
Figure S8 from Comparative Cistromics Reveals Genomic Cross-talk between FOXA1 and ERα in Tamoxifen-Associated Endometrial Carcinomas
Authors: Droog Marjolein , Nevedomskaya Ekaterina , Kim Yongsoo , Severson Tesa , Flach Koen D. , Opdam Mark , Schuurman Karianne , Gradowska Patrycja , Hauptmann Michael , Dackus Gwen , Hollema Harry , Mourits Marian J. , Nederlof Petra , van Boven Hester , Linn Sabine C. , Wessels Lodewyk , van Leeuwen Flora E. , Zwart Wilbert
Published: April 2023

Kaplan-Meier survival plot of endometrial cancer patients who were not treated with tamoxifen for their breast cancer, categorized as ERalpha+/FOXA1+, ERalpha+/FOXA1-, ERalpha-/FOXA1+ or ERalpha-/FOXA1-.
Supplementary Info from PD-1 Blunts the Function of Ovarian Tumor–Infiltrating Dendritic Cells by Inactivating NF-κB
Authors: Karyampudi Lavakumar , Lamichhane Purushottam , Krempski James , Kalli Kimberly R. , Behrens Marshall D. , Vargas Doris M. , Hartmann Lynn C. , Janco Jo Marie T. , Dong Haidong , Hedin Karen E. , Dietz Allan B. , Goode Ellen L. , Knutson Keith L.
Published: April 2023

Supplementary methods and figures. Fig. 1:TIDCs obtained from the ascites from ovarian cancer patients express PD-1 mRNA. Fig. 2: TIDCs obtained from the ascites of ID8 tumor bearing mice express PD-1 mRNA.
Supplementary methods from miR-146b-5p within BCR-ABL1–Positive Microvesicles Promotes Leukemic Transformation of Hematopoietic Cells
Authors: Zhang Hong-Mei , Li Qing , Zhu Xiaojian , Liu Wei , Hu Hui , Liu Teng , Cheng Fanjun , You Yong , Zhong Zhaodong , Zou Ping , Li Qiubai , Chen Zhichao , Guo An-Yuan
Published: April 2023

Supplementary methods for sequencing, regular data analysis and routine experimental methods including primer sequences.
Supplementary Table S5 from miR-146b-5p within BCR-ABL1–Positive Microvesicles Promotes Leukemic Transformation of Hematopoietic Cells
Authors: Zhang Hong-Mei , Li Qing , Zhu Xiaojian , Liu Wei , Hu Hui , Liu Teng , Cheng Fanjun , You Yong , Zhong Zhaodong , Zou Ping , Li Qiubai , Chen Zhichao , Guo An-Yuan
Published: April 2023

Supplementary Table S5. GO enrichment for 8 cluters of DEGs
Supplementary Figure Legends from Ribosomal Protein Rpl22 Controls the Dissemination of T-cell Lymphoma
Authors: Rao Shuyun , Cai Kathy Q. , Stadanlick Jason E. , Greenberg-Kushnir Noa , Solanki-Patel Nehal , Lee Sang-Yun , Fahl Shawn P. , Testa Joseph R. , Wiest David L.
Published: April 2023

This file contains the legends fro supplementary figures 1-4.
Supplementary figures 1-6 from CK2α' Drives Lung Cancer Metastasis by Targeting BRMS1 Nuclear Export and Degradation
Authors: Liu Yuan , Amin Elianna B. , Mayo Marty W. , Chudgar Neel P. , Bucciarelli Peter R. , Kadota Kyuichi , Adusumilli Prasad S. , Jones David R.
Published: April 2023

S1: TNF-induced phosphorylation of BRMS1 is independent of NF-κB. S2: CK2α' endogenously interacts with BRMS1. S3: 14-3-3ε interacts with BRMS1. S4: Activation of CK2α' enhances the invasion potential of NSCLC cells. S5: Activation of CK2α' is incapable of affecting primary tumor growth. S6: CK2α' kinase activity is increased in tumors with lymph nodal metastasis.
Supplemental Information from Aberrant Notch Signaling in the Bone Marrow Microenvironment of Acute Lymphoid Leukemia Suppresses Osteoblast-Mediated Support of Hematopoietic Niche Function
Authors: Wang Weihuan , Zimmerman Grant , Huang Xiaoran , Yu Shuiliang , Myers Jay , Wang Yiwei , Moreton Stephen , Nthale Joseph , Awadallah Amad , Beck Rose , Xin Wei , Wald David , Huang Alex Y. , Zhou Lan
Published: April 2023

Supplemental Materials and Methods This file contains detailed methods of IHC, WB, CHIP assay, luciferase reporter assay, qRT-PCR and 2-photon imaging analysis and etc.
Supplementary Figure 6 from Galectin-3 Cleavage Alters Bone Remodeling: Different Outcomes in Breast and Prostate Cancer Skeletal Metastasis
Authors: Nakajima Kosei , Kho Dhong Hyo , Yanagawa Takashi , Harazono Yosuke , Hogan Victor , Chen Wei , Ali-Fehmi Rouba , Mehra Rohit , Raz Avraham
Published: April 2023

Anti-CRD of Gal-3 inhibits osteoclast cell fusion.
Supplementary Figure 5 from Galectin-3 Cleavage Alters Bone Remodeling: Different Outcomes in Breast and Prostate Cancer Skeletal Metastasis
Authors: Nakajima Kosei , Kho Dhong Hyo , Yanagawa Takashi , Harazono Yosuke , Hogan Victor , Chen Wei , Ali-Fehmi Rouba , Mehra Rohit , Raz Avraham
Published: April 2023

Myosin-2A is a candidate for binding partner of Gal-3.
Supplemental Figure 2 from STAT3 Establishes an Immunosuppressive Microenvironment during the Early Stages of Breast Carcinogenesis to Promote Tumor Growth and Metastasis
Authors: Jones Laura M. , Broz Miranda L. , Ranger Jill J. , Ozcelik John , Ahn Ryuhjin , Zuo Dongmei , Ursini-Siegel Josie , Hallett Michael T. , Krummel Matthew , Muller William J.
Published: April 2023

Supplemental Figure 2: Stat3flx/flx/MTB/MIC mammary glands transform slightly less than the Stat3wt/wt/MTB/MIC mice after 2 weeks of induction.
Supplementary Figure S6 from Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis
Authors: Guo Yabin , Updegraff Barrett L. , Park Sunho , Durakoglugil Deniz , Cruz Victoria H. , Maddux Sarah , Hwang Tae Hyun , O'Donnell Kathryn A.
Published: April 2023

Expression of individual CIS genes are associated with survival of ALL patients.
Supplementary Figure S1 from Macrophage Infiltration and Alternative Activation during Wound Healing Promote MEK1-Induced Skin Carcinogenesis
Authors: Weber Christine , Telerman Stephanie B. , Reimer Andreas S. , Sequeira Ines , Liakath-Ali Kifayathullah , Arwert Esther N. , Watt Fiona M.
Published: April 2023

Flow cytometric characterization of YFP+ cells in skin of PU.1-YFPxInvEE (InvEE) and PU.1-YFPxWT (WT) mice.
Supplementary Table 4 from Antagonizing Integrin β3 Increases Immunosuppression in Cancer
Authors: Su Xinming , Esser Alison K. , Amend Sarah R. , Xiang Jingyu , Xu Yalin , Ross Michael H. , Fox Gregory C. , Kobayashi Takayuki , Steri Veronica , Roomp Kirsten , Fontana Francesca , Hurchla Michelle A. , Knolhoff Brett L. , Meyer Melissa A. , Morgan Elizabeth A. , Tomasson Julia C. , Novack Joshua S. , Zou Wei , Faccio Roberta , Novack Deborah V. , Robinson Stephen D. , Teitelbaum Steven L. , DeNardo David G. , Schneider Jochen G. , Weilbaecher Katherine N.
Published: April 2023

Primers for qPCR
Supplementary Figure S1 from Comprehensive Ex Vivo Transposon Mutagenesis Identifies Genes That Promote Growth Factor Independence and Leukemogenesis
Authors: Guo Yabin , Updegraff Barrett L. , Park Sunho , Durakoglugil Deniz , Cruz Victoria H. , Maddux Sarah , Hwang Tae Hyun , O'Donnell Kathryn A.
Published: April 2023

SB mutagenesis drives growth factor-independence and tumorigenesis and analysis of SB insertions in a high-throughput mutagenesis screen.
Supplementary Table 2 from Antagonizing Integrin β3 Increases Immunosuppression in Cancer
Authors: Su Xinming , Esser Alison K. , Amend Sarah R. , Xiang Jingyu , Xu Yalin , Ross Michael H. , Fox Gregory C. , Kobayashi Takayuki , Steri Veronica , Roomp Kirsten , Fontana Francesca , Hurchla Michelle A. , Knolhoff Brett L. , Meyer Melissa A. , Morgan Elizabeth A. , Tomasson Julia C. , Novack Joshua S. , Zou Wei , Faccio Roberta , Novack Deborah V. , Robinson Stephen D. , Teitelbaum Steven L. , DeNardo David G. , Schneider Jochen G. , Weilbaecher Katherine N.
Published: April 2023

The differentially expressed genes (DEG) lists
Supplementary Table S4 from MSH2 Dysregulation Is Triggered by Proinflammatory Cytokine Stimulation and Is Associated with Liver Cancer Development
Authors: Eso Yuji , Takai Atsushi , Matsumoto Tomonori , Inuzuka Tadashi , Horie Takahiro , Ono Koh , Uemoto Shinji , Lee Kyeryoung , Edelmann Winfried , Chiba Tsutomu , Marusawa Hiroyuki
Published: April 2023

List of somatic mutations in HCC tissues of each mouse type detected by whole-exome sequencing
Supplementary Figure 6 from Antagonizing Integrin β3 Increases Immunosuppression in Cancer
Authors: Su Xinming , Esser Alison K. , Amend Sarah R. , Xiang Jingyu , Xu Yalin , Ross Michael H. , Fox Gregory C. , Kobayashi Takayuki , Steri Veronica , Roomp Kirsten , Fontana Francesca , Hurchla Michelle A. , Knolhoff Brett L. , Meyer Melissa A. , Morgan Elizabeth A. , Tomasson Julia C. , Novack Joshua S. , Zou Wei , Faccio Roberta , Novack Deborah V. , Robinson Stephen D. , Teitelbaum Steven L. , DeNardo David G. , Schneider Jochen G. , Weilbaecher Katherine N.
Published: April 2023

Integrin gene expression of WT and Itgb3-/- BMMs after M1 or M2 polarization
Supplementary Figure Legends from MSH2 Dysregulation Is Triggered by Proinflammatory Cytokine Stimulation and Is Associated with Liver Cancer Development
Authors: Eso Yuji , Takai Atsushi , Matsumoto Tomonori , Inuzuka Tadashi , Horie Takahiro , Ono Koh , Uemoto Shinji , Lee Kyeryoung , Edelmann Winfried , Chiba Tsutomu , Marusawa Hiroyuki
Published: April 2023

Supplementary Figure Legends
Supplementary Figure 3 from Antagonizing Integrin β3 Increases Immunosuppression in Cancer
Authors: Su Xinming , Esser Alison K. , Amend Sarah R. , Xiang Jingyu , Xu Yalin , Ross Michael H. , Fox Gregory C. , Kobayashi Takayuki , Steri Veronica , Roomp Kirsten , Fontana Francesca , Hurchla Michelle A. , Knolhoff Brett L. , Meyer Melissa A. , Morgan Elizabeth A. , Tomasson Julia C. , Novack Joshua S. , Zou Wei , Faccio Roberta , Novack Deborah V. , Robinson Stephen D. , Teitelbaum Steven L. , DeNardo David G. , Schneider Jochen G. , Weilbaecher Katherine N.
Published: April 2023

Integrin beta3 antagonist treatment on early stage breast tumor growth
Supplemental Tables, Figures and Figure Legends from The Beta Subunit of Hemoglobin (HBB2/HBB) Suppresses Neuroblastoma Growth and Metastasis
Authors: Maman Shelly , Sagi-Assif Orit , Yuan Weirong , Ginat Ravit , Meshel Tsipi , Zubrilov Inna , Keisari Yona , Lu Weiyue , Lu Wuyuan , Witz Isaac P.
Published: April 2023

This file includes tables presenting quantitative Real-Time PCR oligonucleotide primers and chemically synthesized peptide segments of human HBB. It also contains figures presenting the influence of separated lung-derived factors on neuroblastoma cell viability, the beta subunit of hemoglobin is elevated in micrometastasis-bearing organs of inoculated mice, single channel confocal images of HBB2 expression in alveolar epithelial and endothelial cells, a high expression of HBB2 is seen in alveolar endothelial cells lining blood vessels of varied diameters in micrometastasis-bearing mice, the beta subunit isolated from native human hemoglobin inhibits neuroblastoma cell viability, human HBB and its derivative peptide Metox do not mediate hemolysis of red blood cells, an intravenous or intranasal treatment of Metox inhibits neuroblastoma local tumor growth and metastasis, and nitric oxide is not influenced by high HBB2 levels in the lungs and serum of micrometastasis-bearing mice.
Supplementary Tables 1 and 2 from Aspirin Suppresses the Acquisition of Chemoresistance in Breast Cancer by Disrupting an NFκB–IL6 Signaling Axis Responsible for the Generation of Cancer Stem Cells
Authors: Saha Shilpi , Mukherjee Shravanti , Khan Poulami , Kajal Kirti , Mazumdar Minakshi , Manna Argha , Mukherjee Sanhita , De Sunanda , Jana Debarshi , Sarkar Diptendra K. , Das Tanya
Published: April 2023

Supplementary Table IA: Pathological and clinical information of the chemotherapy-treated breast cancer patients included in the study. Supplementary Table IB: Pathological and clinical information of the untreated breast cancer patients included in the study. Supplementary Table II: List of primary and secondary antibodies used in the study, Primer sets for RT-PCR, Primer sets for ChIP.
Supplementary Figure and Movie Legend from TGFβ Signaling Intersects with CD103 Integrin Signaling to Promote T-Lymphocyte Accumulation and Antitumor Activity in the Lung Tumor Microenvironment
Authors: Boutet Marie , Gauthier Ludiane , Leclerc Marine , Gros Gwendoline , de Montpreville Vincent , Théret Nathalie , Donnadieu Emmanuel , Mami-Chouaib Fathia
Published: April 2023

Legend for Supplementary Figures S1-S5 and Supplementary Movies.
Supplemental methods, references, figure legends and figures S1-S7 from Myc Induces miRNA-Mediated Apoptosis in Response to HDAC Inhibition in Hematologic Malignancies
Authors: Adams Clare M. , Hiebert Scott W. , Eischen Christine M.
Published: April 2023

Supplemental methods, references, figure legends and figures S1-S7. Figure S1. HDAC inhibition causes decreased Bcl-2 and Bcl-xL protein expression and cell death in multiple hematopoietic malignancies. Figure S2. HDAC inhibition increases global histone acetylation, but no change in transcription at BCL-2 and BCL-XL loci. Figure S3. miR-15 family targets Bcl-2 to induce apoptosis. Figure S4. miR-15 family and let-7a increase in lymphomas upon HDAC inhibition and induce apoptosis. Figure S5. Myc upregulates members of the miR-15 family and let-7a in untransformed cells. Figure S6. MYC ChIPs to the promoters of the miR-15 family and let-7a and HDACi induces miR-15 family and let-7a expression. Figure S7. Myc:Miz-1 interactions do not mediate Bcl-2 and Bcl-XL repression.
Supplementary Figure Legends from Myeloid-Derived Suppressor Cells Endow Stem-like Qualities to Breast Cancer Cells through IL6/STAT3 and NO/NOTCH Cross-talk Signaling
Authors: Peng Dongjun , Tanikawa Takashi , Li Wei , Zhao Lili , Vatan Linda , Szeliga Wojciech , Wan Shanshan , Wei Shuang , Wang Yin , Liu Yan , Staroslawska Elzbieta , Szubstarski Franciszek , Rolinski Jacek , Grywalska Ewelina , Stanisławek Andrzej , Polkowski Wojciech , Kurylcio Andrzej , Kleer Celina , Chang Alfred E. , Wicha Max , Sabel Michael , Zou Weiping , Kryczek Ilona
Published: April 2023

Supplementary Figure 1 MDSC phenotype and suppressor activity Supplementary Figure 2 MDSCs in breast cancer tissues Supplementary Figure 3 Relationship between MDSCs and breast cancer stemness Supplementary Figure 4 MDSCs produce NO and IL-6 and induce tumor STAT3 phosphorylation Supplementary Figure 5 Correlations between CD33, ALDH1A1 and IL6 transcripts in patients with breast cancer
Supplementary Tables S1-S4 from Ubiquitin-Specific Protease 4-Mediated Deubiquitination and Stabilization of PRL-3 Is Required for Potentiating Colorectal Oncogenesis
Authors: Xing Cheng , Lu Xing-Xing , Guo Peng-Da , Shen Tong , Zhang Shen , He Xiao-Shun , Gan Wen-Juan , Li Xiu-Ming , Wang Jing-Ru , Zhao Yuan-Yuan , Wu Hua , Li Jian-Ming
Published: April 2023

Correlation of USP4 expression with patients' clinicopathological variables in 167 cases of CRC (S1); Human USP4 shRNA target sequences (S2); Human USP4 and PRL-3 siRNA target sequences (S3); Primers for qPCR (S4).
Supplementary Figure 4 from Myeloid-Derived Suppressor Cells Endow Stem-like Qualities to Breast Cancer Cells through IL6/STAT3 and NO/NOTCH Cross-talk Signaling
Authors: Peng Dongjun , Tanikawa Takashi , Li Wei , Zhao Lili , Vatan Linda , Szeliga Wojciech , Wan Shanshan , Wei Shuang , Wang Yin , Liu Yan , Staroslawska Elzbieta , Szubstarski Franciszek , Rolinski Jacek , Grywalska Ewelina , Stanisławek Andrzej , Polkowski Wojciech , Kurylcio Andrzej , Kleer Celina , Chang Alfred E. , Wicha Max , Sabel Michael , Zou Weiping , Kryczek Ilona
Published: April 2023

MDSCs produce NO and IL-6 and induce tumor STAT3 phosphorylation
Supplementary Figure 3 from Myeloid-Derived Suppressor Cells Endow Stem-like Qualities to Breast Cancer Cells through IL6/STAT3 and NO/NOTCH Cross-talk Signaling
Authors: Peng Dongjun , Tanikawa Takashi , Li Wei , Zhao Lili , Vatan Linda , Szeliga Wojciech , Wan Shanshan , Wei Shuang , Wang Yin , Liu Yan , Staroslawska Elzbieta , Szubstarski Franciszek , Rolinski Jacek , Grywalska Ewelina , Stanisławek Andrzej , Polkowski Wojciech , Kurylcio Andrzej , Kleer Celina , Chang Alfred E. , Wicha Max , Sabel Michael , Zou Weiping , Kryczek Ilona
Published: April 2023

Relationship between MDSCs and breast cancer stemness
Supplementary Figure 2 from Myeloid-Derived Suppressor Cells Endow Stem-like Qualities to Breast Cancer Cells through IL6/STAT3 and NO/NOTCH Cross-talk Signaling
Authors: Peng Dongjun , Tanikawa Takashi , Li Wei , Zhao Lili , Vatan Linda , Szeliga Wojciech , Wan Shanshan , Wei Shuang , Wang Yin , Liu Yan , Staroslawska Elzbieta , Szubstarski Franciszek , Rolinski Jacek , Grywalska Ewelina , Stanisławek Andrzej , Polkowski Wojciech , Kurylcio Andrzej , Kleer Celina , Chang Alfred E. , Wicha Max , Sabel Michael , Zou Weiping , Kryczek Ilona
Published: April 2023

MDSCs in breast cancer tissues
Supplemental Fig.S4. from HEATR1 Negatively Regulates Akt to Help Sensitize Pancreatic Cancer Cells to Chemotherapy
Authors: Liu Tongzheng , Fang Yuan , Zhang Haoxing , Deng Min , Gao Bowen , Niu Nifang , Yu Jia , Lee SeungBaek , Kim JungJin , Qin Bo , Xie Fang , Evans Debra , Wang Liewei , Lou Wenhui , Lou Zhenkun
Published: April 2023

Supplemental Fig.S4. Akt inhibitor sensitizes pancreatic tumors with HEATR1 knockdown to gemcitabine.
Supplemental Figure 6 from In Situ Tumor Vaccination by Combining Local Radiation and Tumor-Specific Antibody or Immunocytokine Treatments
Authors: Morris Zachary S. , Guy Emily I. , Francis David M. , Gressett Monica M. , Werner Lauryn R. , Carmichael Lakeesha L. , Yang Richard K. , Armstrong Eric A. , Huang Shyhmin , Navid Fariba , Gillies Stephen D. , Korman Alan , Hank Jacquelyn A. , Rakhmilevich Alexander L. , Harari Paul M. , Sondel Paul M.
Published: April 2023

The time-sensitivity of combined radiation and hu14.18-IL2 is not observed with radiation and hu14.18K322A and radiation induces a dose-dependent increase in Fas/CD95 expression.
Supplemental Figure 5 from In Situ Tumor Vaccination by Combining Local Radiation and Tumor-Specific Antibody or Immunocytokine Treatments
Authors: Morris Zachary S. , Guy Emily I. , Francis David M. , Gressett Monica M. , Werner Lauryn R. , Carmichael Lakeesha L. , Yang Richard K. , Armstrong Eric A. , Huang Shyhmin , Navid Fariba , Gillies Stephen D. , Korman Alan , Hank Jacquelyn A. , Rakhmilevich Alexander L. , Harari Paul M. , Sondel Paul M.
Published: April 2023

Immunohistochemistry demonstrates impact of radiation and immunocytokine injection on tumor infiltration by NK and CD8 and CD4-positive T cells.
Supplementary Tables S1-S4 from Chemotherapy-Induced miRNA-29c/Catenin-δ Signaling Suppresses Metastasis in Gastric Cancer
Authors: Wang Yuxuan , Liu Changzheng , Luo Min , Zhang Zhengyi , Gong Jianan , Li Jingjing , You Lei , Dong Lei , Su Rui , Lin Haishuang , Ma Yanni , Wang Fang , Wang Yi , Chen Jie , Zhang Junwu , Jia Hongyan , Kong Yan , Yu Jia
Published: April 2023

Supplementary Tables S1-S4. Comparison of miR-29s expression levels with clinic-pathological features in patients with primary gastric cancer (S1); miR-29s associated with disease-free survival of patients with GC in the training set (S2); Sequences of miR-29s, Ts-miRs, and catenin-ÃŽ' primers (S3); Immunohistochemistry reactions were quantitatively assessed using two methods (S4).
Supplemental Figure 4 from In Situ Tumor Vaccination by Combining Local Radiation and Tumor-Specific Antibody or Immunocytokine Treatments
Authors: Morris Zachary S. , Guy Emily I. , Francis David M. , Gressett Monica M. , Werner Lauryn R. , Carmichael Lakeesha L. , Yang Richard K. , Armstrong Eric A. , Huang Shyhmin , Navid Fariba , Gillies Stephen D. , Korman Alan , Hank Jacquelyn A. , Rakhmilevich Alexander L. , Harari Paul M. , Sondel Paul M.
Published: April 2023

Hu14.18K322A and hu14.18-IL2 do not impact intrinsic cell sensitivity to radiation in vitro and radiation does not impact GD2 expression but GD2-expression is required for the cooperative in vivo interaction of radiation with hu14.18K322A or hu14.18-IL2.
Supplementary Materials and Methods from Chemotherapy-Induced miRNA-29c/Catenin-δ Signaling Suppresses Metastasis in Gastric Cancer
Authors: Wang Yuxuan , Liu Changzheng , Luo Min , Zhang Zhengyi , Gong Jianan , Li Jingjing , You Lei , Dong Lei , Su Rui , Lin Haishuang , Ma Yanni , Wang Fang , Wang Yi , Chen Jie , Zhang Junwu , Jia Hongyan , Kong Yan , Yu Jia
Published: April 2023

Supplementary Materials and Methods. Description of additional methods and procedures used in the study.
Supplementary Figure S9 from Chemotherapy-Induced miRNA-29c/Catenin-δ Signaling Suppresses Metastasis in Gastric Cancer
Authors: Wang Yuxuan , Liu Changzheng , Luo Min , Zhang Zhengyi , Gong Jianan , Li Jingjing , You Lei , Dong Lei , Su Rui , Lin Haishuang , Ma Yanni , Wang Fang , Wang Yi , Chen Jie , Zhang Junwu , Jia Hongyan , Kong Yan , Yu Jia
Published: April 2023

Supplementary Figure S9. E-cadherin expression is determined in GC cells with drugs treatment.
Supplemental Figure 2 from In Situ Tumor Vaccination by Combining Local Radiation and Tumor-Specific Antibody or Immunocytokine Treatments
Authors: Morris Zachary S. , Guy Emily I. , Francis David M. , Gressett Monica M. , Werner Lauryn R. , Carmichael Lakeesha L. , Yang Richard K. , Armstrong Eric A. , Huang Shyhmin , Navid Fariba , Gillies Stephen D. , Korman Alan , Hank Jacquelyn A. , Rakhmilevich Alexander L. , Harari Paul M. , Sondel Paul M.
Published: April 2023

Following radiation, IT injection of hu14.18K322A improves tumor response compared to IV delivery.
Supplemental Figure 1 from In Situ Tumor Vaccination by Combining Local Radiation and Tumor-Specific Antibody or Immunocytokine Treatments
Authors: Morris Zachary S. , Guy Emily I. , Francis David M. , Gressett Monica M. , Werner Lauryn R. , Carmichael Lakeesha L. , Yang Richard K. , Armstrong Eric A. , Huang Shyhmin , Navid Fariba , Gillies Stephen D. , Korman Alan , Hank Jacquelyn A. , Rakhmilevich Alexander L. , Harari Paul M. , Sondel Paul M.
Published: April 2023

Combined treatment with radiation and tumor-specific mAb or IC does not impact mouse weight.
Supplementary Table 2 from Combined Inhibition of DNMT and HDAC Blocks the Tumorigenicity of Cancer Stem-like Cells and Attenuates Mammary Tumor Growth
Authors: Pathania Rajneesh , Ramachandran Sabarish , Mariappan Gurusamy , Thakur Priyanka , Shi Huidong , Choi Jeong-Hyeon , Manicassamy Santhakumar , Kolhe Ravindra , Prasad Puttur D. , Sharma Suash , Lokeshwar Bal L. , Ganapathy Vadivel , Thangaraju Muthusamy
Published: April 2023

Supplementary Table S2 will provide information about the Pathway and gene network analyses
Supplementary Figure legends from Combined Inhibition of DNMT and HDAC Blocks the Tumorigenicity of Cancer Stem-like Cells and Attenuates Mammary Tumor Growth
Authors: Pathania Rajneesh , Ramachandran Sabarish , Mariappan Gurusamy , Thakur Priyanka , Shi Huidong , Choi Jeong-Hyeon , Manicassamy Santhakumar , Kolhe Ravindra , Prasad Puttur D. , Sharma Suash , Lokeshwar Bal L. , Ganapathy Vadivel , Thangaraju Muthusamy
Published: April 2023

Supplementary Figure legends provide clear description for the Supplementary Figures S1-S7.
Supplementary Figure S5 from Chemotherapy-Induced miRNA-29c/Catenin-δ Signaling Suppresses Metastasis in Gastric Cancer
Authors: Wang Yuxuan , Liu Changzheng , Luo Min , Zhang Zhengyi , Gong Jianan , Li Jingjing , You Lei , Dong Lei , Su Rui , Lin Haishuang , Ma Yanni , Wang Fang , Wang Yi , Chen Jie , Zhang Junwu , Jia Hongyan , Kong Yan , Yu Jia
Published: April 2023

Supplementary Figure S5. The suppressive effect of miR-29c on GC formation.
Supplemental Figures from Combined Inhibition of DNMT and HDAC Blocks the Tumorigenicity of Cancer Stem-like Cells and Attenuates Mammary Tumor Growth
Authors: Pathania Rajneesh , Ramachandran Sabarish , Mariappan Gurusamy , Thakur Priyanka , Shi Huidong , Choi Jeong-Hyeon , Manicassamy Santhakumar , Kolhe Ravindra , Prasad Puttur D. , Sharma Suash , Lokeshwar Bal L. , Ganapathy Vadivel , Thangaraju Muthusamy
Published: April 2023

The Supplemental figure file contains severn additional figures. Supplementary figure 1 shows that the Lin-CD49f+CD24+ cells are tumorigenic, Supplementary Figure 2 provide additional evidence for myoepithelial stem and luminal progenitor cells are the targets of genetic mutations/epigenetic modifications that lead to tumor cell of origin, Supplementary Figure 3, shows that the treatment with DNMT and HDAC inhibitors reduces colony formation, Supplementary Figure 4l provide a Flow chart for RNA sequencing analysis, Supplementary Figure 5 shows a heat map for differential expression of genes in normal and in breast cancer, Supplementary Figure 6 shows RAD51AP1 expression in basal breast cancer, and Supplementary Figure 7 shows SPC25 expression in basal breast cancer
Supplementary Figure S10 from Chemotherapy-Induced miRNA-29c/Catenin-δ Signaling Suppresses Metastasis in Gastric Cancer
Authors: Wang Yuxuan , Liu Changzheng , Luo Min , Zhang Zhengyi , Gong Jianan , Li Jingjing , You Lei , Dong Lei , Su Rui , Lin Haishuang , Ma Yanni , Wang Fang , Wang Yi , Chen Jie , Zhang Junwu , Jia Hongyan , Kong Yan , Yu Jia
Published: April 2023

Supplementary Figure S10. mIR-29c and catenin-ÃŽ' expression is determined in GC cells treated with imatinib.
Supplementary Figure Legends from Agonists of the TRAIL Death Receptor DR5 Sensitize Intestinal Stem Cells to Chemotherapy-Induced Cell Death and Trigger Gastrointestinal Toxicity
Authors: Finnberg Niklas K. , Gokare Prashanth , Navaraj Arunasalam , Lang Kuhs Krystle A. , Cerniglia George , Yagita Hideo , Takeda Kazuyoshi , Motoyama Noboru , El-Deiry Wafik S.
Published: April 2023

Supplementary Figure Legends for Supplementary Figures 1-9.
Supplementary Figure Legends from Chemotherapy-Induced miRNA-29c/Catenin-δ Signaling Suppresses Metastasis in Gastric Cancer
Authors: Wang Yuxuan , Liu Changzheng , Luo Min , Zhang Zhengyi , Gong Jianan , Li Jingjing , You Lei , Dong Lei , Su Rui , Lin Haishuang , Ma Yanni , Wang Fang , Wang Yi , Chen Jie , Zhang Junwu , Jia Hongyan , Kong Yan , Yu Jia
Published: April 2023

Legends for Supplementary Figures S1-S10.
Supplementary Figures 1-6 from Treatment of Triple-Negative Breast Cancer with TORC1/2 Inhibitors Sustains a Drug-Resistant and Notch-Dependent Cancer Stem Cell Population
Authors: Bhola Neil E. , Jansen Valerie M. , Koch James P. , Li Hua , Formisano Luigi , Williams Janice A. , Grandis Jennifer R. , Arteaga Carlos L.
Published: April 2023

Figure S1. Inhibition of TORC1/2 promotes a CSC-like phenotype in TNBC cells. Figure S2. TORC1/2 inhibition increases expression of Notch1, FGF1 and Notch1 activity. Figure S3. TORC1/2 inhibition and paclitaxel sustains Notch1 activity and a CSC-like phenotype. Figure S4. Inhibiting Notch1 decreases the CSC-like population induced by inhibition of TORC1/2. Figure S5. TORC1/2 inhibition induces mitochondrial metabolism. Figure S6. Induction of NICD and CSCs upon TORC1/2 inhibition is FGFR-dependent.
Supplementary Figure Legends from Cyclin D1 Promotes Androgen-Dependent DNA Damage Repair in Prostate Cancer Cells
Authors: Casimiro Mathew C. , Di Sante Gabriele , Ju Xiaoming , Li Zhiping , Chen Ke , Crosariol Marco , Yaman Ismail , Gormley Michael , Meng Hui , Lisanti Michael P. , Pestell Richard G.
Published: April 2023

Legends for supplementary figures.
Supplemental Materials and Methods from p28-Mediated Activation of p53 in G2–M Phase of the Cell Cycle Enhances the Efficacy of DNA Damaging and Antimitotic Chemotherapy
Authors: Yamada Tohru , Das Gupta Tapas K. , Beattie Craig W.
Published: April 2023

Western Analysis and Pull-down assay data.
Supplemental data from YAP Mediates Tumorigenesis in Neurofibromatosis Type 2 by Promoting Cell Survival and Proliferation through a COX-2–EGFR Signaling Axis
Authors: Guerrant William , Kota Smitha , Troutman Scott , Mandati Vinay , Fallahi Mohammad , Stemmer-Rachamimov Anat , Kissil Joseph L.
Published: April 2023

Supplemental figures, methods and tables. Figure S1 (related to Figure 1): YAP activity is required for NF2-null Schwann cell proliferation. Figure S2 (related to Figure 2): YAP is required for colony formation in vitro and tumor growth in vivo. Figure S3 (related to Figure 4): COX-2 activity is required for NF2-null Schwann cell growth. Figure S4 (related to Figure 5): SU6656 treatment suppresses EGFR activation. (A&B) Figure S5 (related to Figure 6): YAP activity increases the expression of COX-2 and AREG. Figure S6: Schematic model for the proposed role of YAP in NF2-null schwannoma cells. Table S1: Sequences of siRNAs Table S2: Primer Sequences for RT-PCR
Supplementary Table S8 from Transcriptome Analysis of Recurrently Deregulated Genes across Multiple Cancers Identifies New Pan-Cancer Biomarkers
Authors: Kaczkowski Bogumil , Tanaka Yuji , Kawaji Hideya , Sandelin Albin , Andersson Robin , Itoh Masayoshi , Lassmann Timo , Hayashizaki Yoshihide , Carninci Piero , Forrest Alistair R.R.
Published: April 2023

The overlap between the up regulated genes in FANTOM5 cancer cell lines and TCGA primary tumors, and signatures of pan cancer up-regulated genes reported by Rhodes 2004 and Xu 2007.
Supplementary Table S7 from Transcriptome Analysis of Recurrently Deregulated Genes across Multiple Cancers Identifies New Pan-Cancer Biomarkers
Authors: Kaczkowski Bogumil , Tanaka Yuji , Kawaji Hideya , Sandelin Albin , Andersson Robin , Itoh Masayoshi , Lassmann Timo , Hayashizaki Yoshihide , Carninci Piero , Forrest Alistair R.R.
Published: April 2023

Genes located within 100kb from the promoters of differentially expressed long non-coding RNAs.
Supplementary Table S5 from Transcriptome Analysis of Recurrently Deregulated Genes across Multiple Cancers Identifies New Pan-Cancer Biomarkers
Authors: Kaczkowski Bogumil , Tanaka Yuji , Kawaji Hideya , Sandelin Albin , Andersson Robin , Itoh Masayoshi , Lassmann Timo , Hayashizaki Yoshihide , Carninci Piero , Forrest Alistair R.R.
Published: April 2023

Results of EdgeR Differential Expression Analysis.
Supplementary figure 3 from p73 and IGF1R Regulate Emergence of Aggressive Cancer Stem–like Features via miR-885-5p Control
Authors: Meier Claudia , Hardtstock Philip , Joost Sophie , Alla Vijay , Pützer Brigitte M.
Published: April 2023

Stable expression of miR-885-5p