bluuebunny/crossref_metadata_2025 huggingface dataset:
STATE POLICY ON PUBLIC-PRIVATE PARTNERSHIPS IN THE SPACE INDUSTRY IN THE STRUCTURE OF THE INNOVATIVE ECONOMY OF UKRAINE
Authors: Karpenko Serhii , Holovko Oleh , Vikhliaiev Mykhailo
Published: May 2023

The purpose of the article is to conduct a comprehensive analysis of state policy regarding public-private partnerships in the space industry in the structure of the innovative economy of Ukraine and to develop relevant proposals for the current legislation. The methodological basis of the research is the comparative method, which allows to consider the most effective approaches to the analysis of state policy on public-private partnership in the space industry in the structure of the innovative economy of Ukraine, as well as system-structural, structural-functional methods, the method of moving from the abstract to the concrete. The results of the research are the formulation of the definition of state policy regarding public-private partnership in the space industry, under which it is proposed to understand the activities of public administration subjects, which is a set of formed and legally established goals, tasks, functions and interests, which are directed by these subjects at solving the tasks of development of public-private partnership in the space industry in the structure of innovative economy of Ukraine, and their practical activities for the implementation and achievement of the specified goal. The practical implications of the study are that the means of state policy regarding public-private partnership in the space industry in the structure of the innovative economy of Ukraine are an important tool for the implementation of state policy. The value of the research lies in the fact that the state policy on public-private partnership in the space industry in the structure of the innovative economy of Ukraine performs the role of a means by which in a state-ordered society, in the form of developed state activity, goals determined objectively by public needs and national interests should be correlated to ensure the sustainable development of public-private partnership in the space industry and its available material and intellectual opportunities, subjective desires and goals of the dominant social forces with real historical conditions, which determine the main directions and tasks of state activity to ensure the achievement of these goals.
WELFARE OF THE UKRAINIAN POPULATION: ASSESSMENT OF THE LEVEL AND IMPACT OF KEY FACTORS
Authors: Shumska Svitlana , Gaidai Anastasiia , Blyzniuk Viktoriіa
Published: May 2023

The purpose of this article is to identify the problems that limit the growth of welfare in Ukraine and to provide quantitative estimates of the impact of key factors that influence its level and development trend, taking into account the proposed three-level approach to determining the components of human welfare. Methodology. In order to assess the level and dynamics of changes in the well-being of the Ukrainian population, methods of statistical information analysis, results of sociological surveys and econometric modeling were used. Results. Based on the generalization of theoretical concepts of formation and methods of assessing welfare, the article presents the author's three-level approach to determining the components of human welfare, which includes: the basic or material level, the medium or psychological-emotional level, as well as the higher or spiritual level. Estimates of the pre-war level of welfare of Ukrainians are presented based on the analysis of the results of implementing the task of reducing poverty in Ukraine within the framework of achieving the Sustainable Development Goals (SDG1 – No poverty) as important landmarks on the road to European integration. The results of regression analysis and quantitative assessments of the impact of the key macroeconomic indicators (consumer price inflation, unemployment rate, foreign debt), as well as the indicator of crisis phenomena on the welfare of Ukrainians at different time intervals confirmed the importance of the selected factors explaining the trend of changes in the well-being of the population. The article reflects the negative impact of external factors on the welfare of Ukrainians, namely Covid-19 and Russia's military aggression. The results of sociological surveys are presented, confirming the negative effects of the pandemic and the terrible consequences of the military invasion of Ukraine; showing the losses that will have a long-term impact on various aspects of the lives of Ukrainians. The importance of humanitarian and charitable international assistance to Ukraine was emphasized. Practical value. An extended interpretation of the structure of the concept of well-being allows to consider in practice a wide range of factors that determine it, as well as its quantitative assessments, which are necessary for the justification of policy measures aimed at restoring the level of well-being of Ukrainians as a result of COVID-19 and military aggression, as well as increasing their welfare in the post-war period.
MATEMATİK ÖĞRETMENLERİNİN MATEMATİK DERSLERİNDE TEKNOLOJİ KULLANIMINA YÖNELİK ALGILARI
Authors: TAŞTEPE Mehtap , ALKAN Selçuk
Published: May 2023

Teknolojinin hızlı değişimi eğitim sistemini de etkilemiştir. Bu değişimdeki en önemli öge ise öğretmendir. Bu nedenle öğretmenlerin teknoloji ve teknoloji kullanımına yönelik düşünceleri önemlidir. Özellikle teknolojinin yoğun olarak kullanılabileceği matematik derslerinde öğretmenlerin bu yaklaşımı daha kritiktir. Bu araştırmada ortaokul ve lise matematik öğretmenlerinin eğitimde teknoloji kullanımına yönelik algılarının ve bu doğrultuda teknoloji uyum düzeylerinin belirlenmesi amaçlanmıştır. Bu amaçla çalışmada nicel araştırma yöntemlerinde betimsel desen kullanılmış ve “Matematik Öğretmenleri Teknolojiye Yönelik Algı” anketi araştırmacılar tarafından uyarlanmış ve kullanılmıştır. Verilerin analizinde SPSS paket programından yararlanılmıştır. Araştırma sonuçlarına göre matematik öğretmenlerinin matematik derslerinde teknoloji kullanımına olumlu bakarken, sınıfta teknoloji kullanımına olumsuz baktıkları belirlenmiştir. Köydeki öğretmenlerin şehirdeki öğretmenlere göre daha olumlu baktıkları, yönetici ve velilerin ise olumsuz bir yaklaşım gösterdikleri görülmüştür. 40 yaş altı matematik öğretmenleri, 50 yaş üstü matematik öğretmenlerine göre öğrencilerin teknoloji ile daha iyi matematik öğreneceklerini düşünmektedirler.
Changes in Mediterranean Coastline According to the Coastal Type and Land Cover under Climate Change: The Case of South-east Spain
Authors: Marcet Llorens Pedro , Navarro-Pedreño José
Published: May 2023

Coastline changes were analyzed considering the land cover types and the analysis of the causes that have determined these changes during the past decades. Through the overlapping of aerial photographs and GIS analysis, the results showed that the land surface increased with respect to the previous stage, gaining terrain to the sea, but this increment was caused by anthropogenic processes. In fact, without human pressure, the land surface beside the coastal line would have decreased, especially on the sandy beaches and coastal dunes. Therefore, the beaches are one of the most vulnerable ecosystems and geomorphological systems due to erosion and lack of sediment supply associated with the modified river courses (i.e. by the construction of reservoirs, concrete channeling, etc.), the inner land use changes, and the effects of global warming on the sea level. Climate change studies predict specific increases in the sea level along the coast. The aim of this work is to know if anthropic activity can reverse the effects of sea level rise and coastal erosion. In fact, it has been done for decades with measures aimed to correct impacts and favour economic activity (i.e. maintaining tourism resources) and not from the environmental issues
HUBUNGAN ANTARA EFIKASI DIRI DAN RESILIENSI PADA MAHASISWA YANG SEDANG MENGERJAKAN SKRIPSI
Authors: Nabila Syaikha , Ashshiddiqi Ali Mahmud
Published: May 2023

Pengerjaan skripsi mengandung kompleksitas permasalahan psikologis bagi mahasiswa. Penelitian ini bertujuan untuk mengetahui hubungan antara efikasi diri dengan resiliensi pada mahasiswa yang sedang mengerjakan skripsi. Penelitian kuantitatif ini melibatkan 218 mahasiswa yang sedang mengerjakan skripsi, terdiri dari 58 laki-laki dan 160 perempuan. Pengukuran efikasi menggunakan skala efikasi diri skripsi yang dibuat oleh Sari (2018) berdasarkan teori Bandura (1997), dan resiliensi diukur melalui skala The Connor-Davidson Resilience Scale (CD-RISC) berdasarkan teori Connor dan Davidson (2003). Data yang terkumpul dianalisis dengan teknik uji korelasi Spearman. Hasil penelitian ini menunjukkan bahwa terdapat hubungan positif yang signifikan antara efikasi diri dengan resiliensi pada mahasiswa yang sedang mengerjakan skripsi. Semakin tinggi efikasi diri yang dimiliki oleh mahasiswa yang sedang mengerjakan skripsi maka semakin tinggi pula resiliensinya, dan sebaliknya. Penting bagi mahasiswa untuk memiliki efikasi diri yang tinggi agar mampu untuk bangkit dan beradaptasi dalam menghadapi kesulitan-kesulitan yang muncul selama mengerjakan skripsi.
Contribuições para a prática da psicologia escolar e educacional em situações de luto
Authors: Nascimento Raul Bruno Tibaldi
Published: May 2023

Apesar de situações de luto não serem raras em escolas e de impactarem o desempenho acadêmico dos estudantes, sabe-se da dificuldade em abordar a educação sobre a morte nessas instituições. No intuito de contribuir para a prática de psicólogas escolares e educacionais no manejo de situações de luto, este estudo objetivou revisar o respectivo estado da arte disponível nas bases de dados PePSIC, SciELO Brasil e Catálogo de Teses e Dissertações CAPES, sem restrição de data de publicação. Procedeu-se também a uma análise textual qualitativa de estudos selecionados, por meio de uma Classificação Hierárquica Descendente no software Iramuteq. Os resultados foram categorizados em categorias de análise que indicam, por um lado, o reconhecimento da necessidade de ações de educação sobre a morte e o luto e, por outro lado, as dificuldades de implementá-las no contexto escolar. Assim, propõem-se orientações complementares e específicas para a atuação de psicólogas nesse contexto.
The Influence of Life Stress and Sleep Disturbance on White Matter Integrity
Authors: Kim Minjeong , Lee Jiye , Kim Nambeom , Hwang Yunjee , Lee Kyung Hwa , Lee Jooyoung , Lee Yu Jin , Kim Seog Ju
Published: May 2023

Objective This study investigated whether sleep and stress mutually interact to induce changes in white matter integrity.Methods Diffusion tensor imaging (DTI) was conducted on 36 participants (male=22, female=14; mean age=38.33±12.78 years). Participants were divided into three groups depending on their sleep quality and stress levels: poor sleepers with stress, poor sleepers without stress, and good sleepers. Sleep quality and stress level were evaluated using the Pittsburgh Sleep Quality Index and the Life Experiences Survey, respectively. Fractional anisotropy (FA) values were calculated employing DTI tractography.Results After controlling for age and sex, poor sleepers with stress exhibited a lower FA of the left inferior cerebellar peduncle (ICP) than did poor sleepers without stress (t=2.81, p=0.02). Poor sleepers without stress showed a higher FA of the right middle longitudinal fasciculus (MdLF) than did good sleepers (t=3.35, p=0.006).Conclusion The current study reports the effects of sleep, stress, and their interaction on the white matter integrities of the ICP and MdLF. ICP change seems to be associated with sleep disturbances related to stress, while MdLF change would be associated with sleep disturbances unrelated to stress.
Psychometric Properties of Assessment Tools for Depression, Anxiety, Distress, and Psychological Problems in Breast Cancer Patients: A Systematic Review
Authors: Park Heeseung , Kim Kyoung-Eun , Moon Eunsoo , Kang Taewoo
Published: May 2023

Objective Various and accurate psychiatric assessments in patients with breast cancer who frequently suffer from psychological problems due to long-term survivors are warranted. This systematic review aimed to investigate the current evidence on psychometric properties of psychiatric assessment for evaluating psychological problems in breast cancer patients.Methods This systematic review progressed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline. Four electronic databases such as Web of Science, PubMed, Embase, and Cumulative Index to Nursing and Allied Health Literature were searched. This study protocol was registered on Open Science Framework.Results Of the 2,040 articles, 21 papers were finally included. Among them, only five studies showed the performance of psychiatric assessment tools. Among 13 assessment tools used in the selected articles, the Hospital Anxiety and Depression Scale (HADS), Distress Thermometer (DT), or Mini-Mental Adjustment to Cancer Scale was frequently used for the evaluation of psychological problems. The DT and Psychosocial Distress Questionnaire-Breast Cancer showed acceptable performances for the prediction of depression and anxiety assessed by the HADS.Conclusion This systematic review found psychiatric assessment tools with acceptable reliability and validity for breast cancer patients. However, comparative studies on reliability and validity of various scales are required to provide useful information for the selection of appropriate assessment tools based on the clinical settings and treatment stages of breast cancer. Joint research among the fields of psychiatry and breast surgery is needed for research to establish the convergent, concurrent, and predictive validity of psychiatric assessment tools in breast cancer patients.
Cluster Analysis on the Mental Health States in a Community Sample of Young Women During Pre-Pregnancy, Pregnancy, or the Postpartum Period
Authors: Lim Hyun Ju , Moon Eunsoo , Kim Kyungwon , Suh Hwagyu , Park Jeonghyun , Kim Du-Ri , Park Jong-Hwan , Shin Myung-Jun , Lee Yean-Hwa
Published: May 2023

Objective It is necessary to identify the mental health types of young women considering the importance of the mental health during the peripartum period. This study aimed to classify the mental health types in a community sample of young women with pre-pregnancy, pregnancy, or the postpartum period.Methods A total of 293 young women during pre-pregnancy, pregnancy, or the postpartum period were included in this study. The clinical characteristics of depression, anxiety, perceived stress, and quality of life were assessed. The clinical characteristics of the subject were classified by cluster analysis and compared by analysis of variance.Results From the cluster analysis, the subjects were classified into three groups. Cluster 1 showed significantly lower depression and anxiety and higher quality of life than those of cluster 2 and 3. Cluster 2 demonstrated significantly higher depression and anxiety and lower quality of life than those of cluster 3 and 1. Cluster 3 represented the intermediate levels between cluster 2 and 1.Conclusion This study suggested that young women during pre-pregnancy, pregnancy, or the postpartum period might be in a good mental health group, a high-risk group requiring active monitoring, or a group in need of treatment. By monitoring mental health, the groups with high risk or requiring treatment could be discovered and proper management for prevention or improvement of mental health and quality of life can be provided.
300, una transposición excesiva. Elementos semióticos que configuran al héroe
Authors: Lomeli Carrillo Héctor Isaac
Published: May 2023

A diferencia de la novela gráfica 300 de Frank Miller, la película de Zack Snyder presenta la batalla de las Termópilas en una narración enmarcada; técnica narrativa que permite hilar tramas y componentes que no existían en la obra de Miller. Así, cristaliza los logros del Rey Leónidas I de Esparta y, al mismo tiempo, maximiza —con personajes fantásticos— el poder y la tiranía de su enemigo persa, Jerjes I. El discurso visual, además de magnificar, aumenta las diferencias culturales entre Medio Oriente y Occidente, con lo cual presenta estereotipos de belleza, prejuicios religiosos, deleite por lo bélico, tintes homofóbicos, puntos de vista sobre la esclavitud y la libertad; discursos encubiertos por la ampliación estética de la novela gráfica llevada a la pantalla grande. La transposición, estrenada en el 2007, recurre a múltiples efectos cinematográficos de producción y postproducción para ofrecernos, en un espacio oscuro y superpuesto, la prédica vociferada y apócrifa de Leónidas I, rey de Esparta.
Ellas pornotópicas: espacios de visibilidad y reversibilidad
Authors: Avila Moreno Lucio Rogelio
Published: May 2023

En el presente artículo se hace una comparación de la construcción cinematográfica de los personajes protagónicos de las películas Belle de Jour (1967) de Luis Buñuel y Elles (2011) de Malgorzata Szumowska: la esposa burguesa en contraposición a la prostituta. Dicha comparación ayuda a delinear la esfera de los géneros entre lo privado y lo público, los binarios femenino y masculino, lo permitido y lo prohibido para las esposas, y la sobrevivencia de la prostituta al enclave de su propia película. Se emplean los términos posdoméstico y pornotópico, propuestos por Beatriz Preciado en su libro Pornotopía, quien a la vez se sustenta en la teoría de Michel Foucault sobre los espacios heterotópicos y las sexualidades periféricas.
Los olvidados: el rostro del otro y la vida precaria
Authors: Virto Martínez Centeocihuatl , Reynoso de la Paz Manuel
Published: May 2023

En este artículo se propone un acercamiento a la película Los olvidados (1950) de Luis Buñuel a partir de las siguientes categorías de análisis: en primer lugar, se construye quiénes son los olvidados de acuerdo con la noción de olvido establecida por Paul Ricoeur; en segundo lugar, se reflexiona sobre la idea de rostro de Emmanuel Lévinas y se hace una comparación entre las figuras de la precariedad utilizadas por éste y los personajes que Buñuel presenta en su película; finalmente, se exponen las ideas de vulnerabilidad y precariedad referidas en la obra de Judith Butler y se incorporan al análisis de Los olvidados de Buñuel.
El discurso ideológico de la Revista de la Facultad de Humanidades (1959-1960), de la UASLP
Authors: Villasana Mercado Irma Guadalupe
Published: May 2023

En la década de los cincuenta, en San Luis Potosí, había un descontento generalizado por el gobierno autoritario de Gonzalo N. Santos. La clase media universitaria se organizó en torno a Salvador Nava para desmantelar el poder santista. Una institución central para ejercer la disidencia fue la Facultad de Humanidades (1955-1962) de la Universidad Autónoma de San Luis Potosí (UASLP). Este trabajo da cuenta del concepto de humanismo ahí propuesto, a través de la interpretación de los discursos programáticos de su órgano de difusión, la Revista de la Facultad de Humanidades (1959-1960), desde la perspectiva de la historia intelectual. Se parte del supuesto de que los colaboradores de esta publicación apuestan por una propuesta estética existencialista —a partir de la recepción de la obra de Croce, Ortega y Gasset y Sartre— para contravenir el discurso hegemónico santista. La aportación central de este artículo es mostrar cómo se construye una subjetividad política crítica desde el ejercicio intelectual a través de la escritura.
Meaning of life karyawan penderita kanker
Authors: Bintang Suntaka I Dewa Gede , Suhariadi Fendy
Published: May 2023

Penelitian ini bertujuan untuk mengetahui lebih dalam mengenai makna hidup dari individu karyawan dalam perusahaan yang telah divonis terkena penyakit kanker. Kanker berasal dari kata yunani yaitu karkinos, yang berarti undang karang menyerupai istilah umum untuk ratusan tumor ganas yang berbeda satu sama lain. Kanker juga adalah istilah yang digunakan untuk penyakit di mana sel-sel abnormal membelah tanpa kontrol dan mampu menyerang jaringan lain. Penelitian ini merupakan penelitian kualitatif yang menggunakan metode fenomenologi. Hasil penelitian ini mengatakan bahwa makna hidup dalam penelitian ini ada kaitannya dengan motivasi kerja. Motivasi kerja partisipan adalah untuk memenuhi hirarki kebutuhan maslow. Selain itu bekerja juga sebagai strategi koping untuk partisipan agar tidak stress terhadap penyakit yang dideritanya hal ini disebut emotion focused coping. Hal inilah yang membuat para partisipan tetap bekerja meskipun memiliki penyakit kanker dengan stadium akhir.
Systematic Literature Review: Teleworking dan Kinerja Karyawan pada Era Pandemi
Authors: Rizqi Abdillah Rahman
Published: May 2023

Pandemi Covid-19 memaksa berbagai sektor perusahaan untuk merubah sistem kerjanya menjadi Work From Home (WFH) untuk mengurangi penyebaran virus Covid-19. WFH atau teleworking merupakan praktik kerja yang sedang berkembang, dimana karyawan bekerja pada suatu tempat di luar kantor selama beberapa kali dalam seminggu (Lamond, Daniels, & Standen, 1997). Penelitian ini bertujuan untuk mengetahui efektivitas WFH terhadap kinerja karyawan di era pandemi dan faktor-faktor yang mempengaruhinya. Metode yang digunakan adalah Systematic Literature Review dengan membatasi artikel yang terbit pada rentang waktu selama pandemi Covid-19 tahun 2020 hingga 2022. Hasil penelusuran yang didapatkan bahwa Teleworking atau WFH memiliki pengaruh terhadap kinerja karyawan yang dipengaruhi beberapa faktor, di antaranya faktor individu, faktor pekerjaan, faktor lingkungan.
PENGARUH INFLASI TERHADAP PERTUMBUHAN EKONOMI DI INDONESIA
Authors: Mayasari Febi , Mahinshapuri Yaqutta Fahra
Published: May 2023

The issue of inflation is a very important indicator in terms of maintaining economic stability. It can be said that inflation is one of the important factors influencing the economic growth of a country. Economic growth is a goal to be achieved by every country. Keynesian theory states that in the short run, national output and employment are determined primarily by aggregate demand. When the inflation rate increases, which is followed by an increase in interest rates, investors will borrow capital from banks to expand their investment range, which in turn will affect economic growth. This study aims to analyze the effect of inflation on economic growth in Indonesia using the OLS model. This study uses a quantitative approach method. Data collection method using secondary data. The data analysis method used in this research is simple linear regression analysis using the Ordinary Least Square (OLS) method with calculations performed through the SPSS program. Based on the results of the tests that have been carried out, it is found that inflation has a negative effect on economic growth
MEMBENTUK MORAL PERDAMAIAN DENGAN MEMADUKAN NILAI-NILAI KRISTEN DAN BUDAYA LOKAL MASYARAKAT TORAJA
Authors: Amanda Wisnu
Published: May 2023

Kajian ini berusaha menyelidiki bagaimana nilai-nilai Kristiani dan budaya Toraja dapat digabungkan untuk menumbuhkan keharmonisan moral. Suku Toraja memiliki budaya yang kaya dan rumit yang terkait erat dengan alam dan masyarakatnya sendiri. Seiring berkembangnya pengaruh nilai-nilai Kristiani di Indonesia, beberapa individu meninggalkan akar budayanya. Dalam upaya mencapai keselarasan moral, penelitian ini berupaya mengintegrasikan nilai-nilai Kristiani dengan budaya Toraja. Nilai-nilai Kristiani dan budaya lokal Toraja dapat saling melengkapi dan mendukung dalam mewujudkan perdamaian dan keharmonisan sosial. Kedua budaya berbagi nilai mengandalkan intuisi dan spiritualitas untuk bimbingan dalam situasi ambigu, seperti yang ditunjukkan oleh pelajaran dari pandemi Covid-19. Di tengah banjirnya informasi negatif yang bisa memicu konflik, agama bisa menjadi penggerak nilai-nilai perdamaian dalam kehidupan manusia. Maka, sangat penting untuk memasukkan nilai-nilai Kristiani dan budaya Toraja ke dalam kode etik untuk kerukunan.Kearifan lokal Toraja menunjukkan bahwa manusia memiliki kapasitas rasional yang memungkinkannya mengembangkan budaya dan berkomunikasi. Dengan memasukkan nilainilai Kristiani ke dalam budaya Toraja, individu dapat menumbuhkan moral cinta damai dan hidup rukun dan damai. Penelitian ini berkontribusi pada terciptanya perdamaian sesuai dengan tatanan budaya dan identitas masing-masing individu.
Filsafat Stoicisme dan hubungan manusia dengan Alam
Authors: Andini Mispa
Published: May 2023

Abstrak:Dalam pandangan Stoic, manusia adalah bagian integral dari alam dan harus hidup sesuai dengan kodratnya. Ajaran-ajaran Stoic tentang hubungan manusia dengan alam semesta. Kami mengeksplorasi konsep "logos" Stoic yang menghubungkan manusia dengan keteraturan alam dan memperkuat ikatan mereka dengan alam semesta. Kami juga menelaah pandangan Stoic tentang alam sebagai guru dan sumber hikmat yang tak terbatas. Stoic percaya bahwa melalui pemahaman yang lebih dalam tentang alam semesta, manusia dapat mencapai kebijaksanaan dan kebahagiaan sejati. Dalam konteks ini, kami menggali bagaimana Stoicisme memandang manusia sebagai bagian tak terpisahkan dari alam, yang diharapkan hidup dalam keselarasan dengan prinsip-prinsip alamiah. Kami menyoroti pentingnya memperhatikan keindahan alam, keadaan alamiah, dan siklus kehidupan dalam memandang keberadaan manusia. Melalui telaah literatur dan analisis konseptual, kami menyimpulkan bahwa pemahaman Stoic tentang hubungan manusia dengan alam semesta menawarkan wawasan yang berharga dalam menghadapi tantangan hidup dan mencapai kebahagiaan yang lebih mendalam.
Differential expression of BTAF1 in cancer of the skin: malignant melanoma.
Authors: Mamoor Shahan
Published: May 2023

Skin cancer is diagnosed in nearly 1.5 million patients each year (1). While patients with basal and squamous cell carcinomas are provided with 5-year survival rates at nearly 100% and 90%, respectively, patients diagnosed with cutaneous melanoma (metastatic melanoma) are provided 5-year survival rates at 91.4% at stage I and 24.6% at stage IV (2-5). We mined published microarray datasets (6, 7) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with the deadliest type of skin cancer, malignant melanoma. We found significant differential expression of the gene encoding B-TFIID TATA-box binding protein-associated factor 1, BTAF1, when comparing melanoma tumor tissue from the human skin to the tissue of origin. BTAF1 mRNA was present at significantly lower quantities in melanoma tissues as compared to normal tissues from the skin. Analysis of human survival data revealed that expression of BTAF1 in melanoma tissues was not correlated with overall survival in patients with malignant melanoma. BTAF1 expression changes may be important for the initiation or progression of malignant melanoma in humans.
SASTRA MELAYU KLASIK DAN MODERN
Authors: Alfalah Riski
Published: May 2023

Kumpulan makalah ini bersumber dari pemikiran mahasiswa kelas 2021C, Program Studi Pendidikan Bahasa dan Sastra Indonesia, Jurusan Bahasa dan Seni, Fakultas Keguruan dan Ilmu Pendidikan, Universitas Riau.
Concerns about an article
Authors: Maged Ahmed Mohamed
Published: May 2023

We have read the article entitled “Aspirin plus heparin or aspirin alone in women with recurrent miscarriage.” (1) that was published in your journal with great interest. However, some of its data was not fully clear. So, we searched the trial registration (2) and the changes that were made by the authors over time and the final published article. These evaluations revealed major concerns
Public Law and the Protection of Constitutional Rights
Authors: Hassan Ali
Published: May 2023

Public Law and the Protection of Constitutional Rights
TEKNOLOGI PEMBELAJARAN DI ERA 4.0
Authors: Nabilatuzzahwa
Published: May 2023

Ilmu pengetahuan semakin berkembang dari masa ke masa. Perkembangan ilmu pengetahuan ini mendukung untuk terciptanya teknologi-teknologi baru yang menandai adanya kemajuan zaman. Hingga kini, teknologi yang berkembang sudah memasuki tahap digital (Lestari, 2018). Media digital adalah konten digital yang dapat disebarluaskan melalui internet atau jaringan komputer (Erimurti, 2012).Perkembangan teknologi informasi beberapa tahun belakangan ini berkembang dengan pesat, sehingga dengan adanya perkembangan ini telah mengubah paradigma masyarakat dalam mencari serta mendapatkan informasi, yang tak lagi terbatas pada sebuah informasi surat kabar, audio visual maupun elektronik, tetapi juga sumber-sumber informasi lainnya seperti melalui jaringan Internet(Fatwa, 2021). Teknologi Pendidikan berperan utama sebagai disiplin ilmu yang memfasilitasi pembelajaran agar terjadi secara efektif dan efisien.(Pratama & Haryanto, 2018)
Assessing the Effects of In-service Training on the Performance of Ghanaian Basic School Social Studies Teachers
Authors: Yeboah Francis , Dangah Muriel Mavis , Adjei Eric Kofi
Published: May 2023

This study investigated the effects of in-service training on Social Studies teachers’ performance in Ghana. The study area was Offinso Municipality in the Ashanti Region. To achieve this purpose, the study examined the various training programmes available to teachers, the effect of training on the teachers’ performance and explored ways to improve teachers training at Offinso Municipality. The study adopted a quantitative approach and research design was descriptive survey. Questionnaire was used in getting data from respondents. The population of the study consisted of 550 teachers at Offinso Municipality in the Ashanti Region. However, 232 teachers were sampled using simple random technique. Data was collected and analyzed using quantitative analysis. The study found out that external or extramural courses were prepared for teachers as well as industrial experiences. The study found out that training among Social Studies teachers at Offinso Municipality had a moderate positive significant relationship with teachers’ performance. It was also found out that teachers’ in-service training could be improved at Offinso Municipality when copies of training modules were given to teachers after training to serve as reference materials. The study concluded that in-service training is statistically significant and positively related to Social Studies teachers’ performance. Finally, the study recommends that Ghana Education Service should improve upon its in-service training and development policy to be consistent with the needs of teachers in general.
Statistical Analysis Plan for the Fludrocortisone Dose Response Relationship in Septic Shock (FluDReSS) trial
Authors: Billot Laurent , Venkatesh Baasubramanian , Finfer Simon , Cohen Jeremy , Rajbhandari Dorrilyn , Myburgh John , Walsham James
Published: May 2023

FluDReSS is an open label randomised controlled clinical trial of three different dosing regimens of fludrocortisone in critically ill patients with septic shock compared to no fludrocortisone. The primary objective is to determine whether the combination of hydrocortisone plus fludrocortisone compared to hydrocortisone alone reduces time to shock reversal. This detailed statistical analysis plan (SAP) was written by the trial statistician and study investigators prior to unblinding.
PENTINGNYA DISIPLIN DALAM PENDIDIKAN KARAKTER BAGI PEMBENTUKAN IMAN MASYARAKAT TORAJA
Authors: Batara Apriliani
Published: May 2023

Tujuan kajian dalam tulisan ini yaitu untuk memaparkan tentang pentingnya sebuah sikap disiplin untuk pembentukan karakter sehingga memunculkan pemahaman yang baik tentang  budaya khusususnya kebudayaan masyarakat toraja. Dengan memiliki sikap disiplin seseorang dapat bertanggung jawab tehadap apa yang telah di percayakan kepadanya. Adanya pemahaman yang baik tentang kepemimpinan , sesorang  juga di harapkan mampu untuk menjadi seorang pemimpin yang baik, baik dalam lingkungan masayarakat maupun dalam lingkungan gereja.
Kebijakan Moneter Perspektif Islam
Authors: gunawan sahrul
Published: May 2023

resume ini dibuat untuk memenuhi tugas mata kuliah ekonomi mikro syariah
Differential expression of CARD18 in cancer of the skin: malignant melanoma.
Authors: Mamoor Shahan
Published: May 2023

Skin cancer is diagnosed in nearly 1.5 million patients each year (1). While patients with basal and squamous cell carcinomas are provided with 5-year survival rates at nearly 100% and 90%, respectively, patients diagnosed with cutaneous melanoma (metastatic melanoma) are provided 5-year survival rates at 91.4% at stage I and 24.6% at stage IV (2-5). We mined published microarray datasets (6, 7) to determine in an unbiased fashion and at the level of the transcriptome genes most differentially expressed in the primary tumors of patients with the deadliest type of skin cancer, malignant melanoma. We found significant differential expression of the gene encoding caspase recruitment domain family member 18, CARD18, when comparing melanoma tumor tissue from the human skin to the tissue of origin. CARD18 mRNA was present at significantly lower quantities in melanoma tissues as compared to normal tissues from the skin. Analysis of human survival data revealed that expression of CARD18 in melanoma tissues was correlated with overall survival in patients with malignant melanoma. CARD18 expression changes may be important for the initiation or progression of malignant melanoma in humans.
Linking 3D long-term slow-slip cycle models with rupture dynamics: the nucleation of the 2014 Mw 7.3 Guerrero, Mexico earthquake
Authors: Li Duo , Gabriel Alice-Agnes
Published: May 2023

Slow slip events (SSEs) have been observed in spatial and temporal proximity to megathrust earthquakes in various subduction zones, including the 2014 $M_\mathrm{w}$7.3 Guerrero, Mexico earthquake which was preceded by a $M_\mathrm{w}$ 7.6 SSE. However, the underlying physics connecting SSEs to earthquakes remains elusive. Here, we link 3D slow-slip cycle models with dynamic rupture simulations across the geometrically complex flat-slab Cocos plate boundary. Our physics-based models reproduce key regional geodetic and teleseismic fault slip observations on timescales from decades to seconds.We find that accelerating SSE fronts transiently increase shear stress at the down-dip end of the seismogenic zone, modulated by the complex geometry beneath the Guerrero segment. The shear stresses cast by the migrating fronts of the 2014 $M_\mathrm{w}$ 7.6 SSE are significantly larger than those during the three previous episodic SSEs that occurred along the same portion of the megathrust. We show that the transient stresses caused by this SSE are large enough to nucleate earthquake dynamic rupture. However, additional frictional asperities in the seismogenic part of the megathrust are required to explain the observed complexities in the coseismic energy release and static surface displacements of the 2014 $M_\mathrm{w}$7.3 Guerrero earthquake. We conclude that it is crucial to jointly analyze the long- and short-term interactions and complexities of SSEs and megathrust earthquakes across several (a)seismic cycles accounting for megathrust geometry. Our study has important implications for identifying earthquake precursors and understanding the link between transient and sudden megathrust faulting processes.
Auditory distractors are processed but do not interfere with visual search of any difficulty
Authors: Mandal Ananya , Röer Jan Philipp , Liesefeld Anna M. , Liesefeld Heinrich R
Published: May 2023

People often report being distracted during their visual tasks, such as monitoring the road ahead, by task-irrelevant sounds, for example, a baby crying on the backseat. When we first tried to study the effect of auditory distraction on visual-search performance in the laboratory using the highly sensitive additional-singleton paradigm – to our surprise – several types of auditory distractors reliably failed to cause any substantial interference. We explained these findings with a powerful attentional mechanism that can shield visual search from interference by irrelevant sounds. In the present study, we put this mechanism to a stress test based on insights from research on auditory distraction. It has been shown that whether an auditory distractor causes interference often hinges on the difficulty of the employed task. However, across three levels of search-task difficulty, we here reliably replicate the pattern we had observed before: While an unpredictably presented auditory distractor sped up responses, it also increased error rates, which is an effect on the employed speed-accuracy tradeoff rather than on search performance proper. Thus, the auditory distractor was processed to some extent (because it would otherwise not affect the speed-accuracy tradeoff) but does not interfere with overall search performance independent of task difficulty.
The relationship between environmental statistics and predictive gaze behaviour during a manual interception task: Eye movements as active inference
Authors: Harris David , Vine Samuel James , Wilson Mark , Arthur Tom
Published: May 2023

Human observers are known to frequently act like Bayes-optimal decision makers and there is growing evidence that the deployment of the visual system may similarly be driven by probabilistic mental models of the environment. We tested whether eye movements during a dynamic interception task were indeed optimised according to Bayesian inference principles. Forty-one participants intercepted oncoming balls in a virtual reality racquetball task across five counterbalanced conditions in which the relative probability of the onset location was manipulated. Analysis of pre-onset gaze positions indicated that eye position tracked the true distribution of onset location, indicating that the gaze system spontaneously adhered to environmental statistics. Eye position did not, however, minimise the distance between the target and foveal vision in a fully probabilistic way, and instead often reflected a ‘best guess’ about onset location. Trial-to-trial changes in gaze position were found to be better explained by Bayesian learning models (Hierarchical Gaussian Filter) than associative learning models. Additionally, parameters relating to the precision of beliefs and prediction errors extracted from the participant-wise models were related to both task-evoked pupil dilations and variability in gaze positions, providing further evidence that probabilistic context was reflected in spontaneous gaze dynamics.
Yliopisto-opiskelijoiden motivaatioprofiilit koronapandemian aikana ja toiveet opetuksen toteuttamisesta jatkossa
Authors: Tuominen Heta , Pikkarainen Paavo , Hirvonen Riikka , Juntunen Henriikka , Viljaranta Jaana , Niemivirta Markku
Published: May 2023

Tämän tutkimuksen ensimmäisenä tehtävänä oli tarkastella, minkälaisia motivaatioprofiileja – odotusten, arvostusten ja kustannusten painotuksia – voidaan tunnistaa yliopisto-opiskelijoilla koronapandemian aikana. Tutkimuksen toisena tehtävänä oli tutkia, miten opintojen vaihe on yhteydessä motivaatioon, eli miten eri aikoihin opintonsa aloittaneet (esimerkiksi ennen koronapandemiaa aloittaneet vs. pandemian aikana aloittaneet) opiskelijat jakautuvat motivaatioryhmiin. Kolmantena tehtävänä oli tarkastella, minkälaisia toiveita eri tavoin motivoituneilla opiskelijoilla on opetuksen toteuttamisesta jatkossa (lähi-, hybridi- vai etäopetus). Tutkimuksen aineisto kerättiin sähköisellä kyselylomakkeella keväällä 2021. Tutkimukseen osallistui 1718 eri alojen yliopisto-opiskelijaa. Henkilösuuntautuneen tutkimusotteen mukaisesti opiskelijat ryhmiteltiin eri motivaatioprofiileihin TwoStep-ryhmittelyanalyysillä. Tunnistimme viisi erilaista motivaatioprofiilia: heikosti motivoituneet kuormittuneet (30 %), kohtalaisen motivoituneet (25 %), kuormittuneet hyötyorientoituneet (16 %), hyötyorientoituneet (16 %) ja myönteisen kunnianhimoiset (13 %). Ristiintaulukoinnin mukaan alkuvaiheen opiskelijoita oli kielteisimmässä, heikosti motivoituneiden kuormittuneiden, ryhmässä odotettua vähemmän. Eri tavoin motivoituneet opiskelijat erosivat siinä, minkälaisia toiveita heillä oli opetuksen toteuttamisesta pandemian jälkeen. Heikosti motivoituneet kuormittuneet kaipasivat takaisin lähiopetukseen, kun taas myönteisen kunnianhimoiset toivoivat voivansa jatkaa opintojaan etänä tulevaisuudessakin. Vaikuttaa siis siltä, että toisille opiskelijoille etäopetuksella voi olla kielteisempiä seurauksia kuin toisille.
Corticospinal excitability reductions during action preparation and action stopping in humans: Different sides of the same inhibitory coin?
Authors: Bundt Carsten , Huster Rene
Published: May 2023

Motor functions and cognitive processes are closely associated with each other. In humans, this linkage is reflected in motor system state changes both when an action must be prepared and stopped. Single-pulse transcranial magnetic stimulation showed that both action preparation and action stopping are accompanied by a reduction of corticospinal excitability, referred to as preparatory and response inhibition, respectively. While previous efforts have been made to describe both phenomena extensively, an updated and comprehensive comparison of the two phenomena is lacking. To ameliorate such deficit, this review focuses on the role and interpretation of single-coil (single-pulse and paired-pulse) and dual-coil TMS outcome measures during action preparation and action stopping in humans. To that effect, it aims to identify commonalities and differences, detailing how TMS-based outcome measures are affected by states, traits, and psychopathologies in both processes. Eventually, findings will be compared, and open questions will be addressed to aid future research.
Social Inequality and Digitization in Modern Societies: A Systematic Literature Review on the Role of Ethnicity, Gender, and Age
Authors: Verwiebe Roland , Bobzien Licia , Fritsch Nina-Sophie , Buder Claudia
Published: May 2023

The digitization process has triggered a profound transformation of modern societies. It encompasses a broad spectrum of technical, social, political, cultural and economic developments related to the mass use of computer- and internet-based technologies. It is now becoming increasingly clear that digitization is also changing existing structures of social inequality and that new structures of digital inequality are emerging. This is shown by a growing number of recent individual studies. In this paper, we set ourselves the task of systematizing this new research within the framework of an empirically supported literature review. To do so, we use the PRISMA model for literature reviews and focus on three central dimensions of inequality - ethnicity, gender, and age - and their relevance within the discourse on digitization and inequality. The empirical basis consists of journal articles published between 2000 and 2020 and listed on the Web of Science, as well as an additional Google Scholar search, through which we attempt to include important monographs and contributions to edited volumes in our analyses. Our text corpus thus comprises a total of 281 articles. Empirically, our literature review shows that unequal access to digital resources largely reproduces existing structures of inequality; in some cases, studies report a reduction in social inequalities as a result of the digitization process.
Critical Approaches to Private Education in the Global South
Authors: Inglis Patrick
Published: May 2023

This article highlights the key themes that animate the critical discourse on private education initiatives targeting poor children in the Global South. Scholars in the field uniformly reject the idea that public-private partnerships, independent private schools, and various subsidy and voucher programs are best suited to addressing underlying issues of equity and quality that plague public education systems in developing world contexts. But they tend to adopt one of two markedly different lines of analysis in drawing attention to the issue. Some scholars, for instance, use empirical evidence to show how low-fee private schools fall short of delivering on promises to address the needs of all children and enhancing basic literacy and numeracy scores in comparison to public schools. Other scholars, however, prefer to map elaborate networks of people and money to reveal how private education in the Global South is guided by power and profit. The paper outlines the moral and analytic interests that guide these two approaches to the challenge private education presents, while also making the case for an additional mode of analysis that would test the democratic and social justice claims that feature in mission statements of larger foundations and institutions that operate in vulnerable societies.
The Physical Education Teacher's Workbook As a Tool For Improving His Professional Competence
Authors: Aksonova O.
Published: May 2023

State requirements actualize the need to find some effective tools in the system of improving the qualifications of a modern teacher. This is especially intensified in the conditions of forced remote and mixed education of children and teenagers which is due to the full-scale invasion of the Russian Federation into Ukraine. The article presents the workbook "STEP to a new Physical Education lesson", the content of which was tested during some educational trainings in the system of postgraduate teacher education. This latest development is positioned as a tool in the program of improving the professional competencies of a modern Physical Education teacher. It was used both by regional trainers and training participants in face-to-face and distance learning formats from October 2021 to August 2022. The training and, accordingly, the structure of the workbook consisted of the introduction and four main parts which according to their content submit to the mastering the methods of the new lesson of Physical Education at NUS according to the leading directions: 1 - competent, 2 - smart, 3 - healthy, 4 - creative lesson. The training included 21 interactive exercises. Learning according the content of each part of the training ended with online testing. All exercises in the workbook are presented in such a way that they can be performed both in distance and face-to-face learning formats. The effect of the training using the workbook was determined by online testing, which took place directly after the completion of each section of the training program. The second testing took place after several months of work of teachers, who completed the training, with fifth grade students of NUS. The positive dynamics proved the effectiveness of using the workbook during trainings and throughout teachers’ own pedagogical practice.