bluuebunny/crossref_metadata_2025 huggingface dataset:
Single-cell transcriptomics of the human parasite Schistosoma mansoni first intra-molluscan stage reveals tentative tegumental and stem-cell regulators
Authors: Diaz Soria Carmen L. , Attenborough Teresa , Lu Zhigang , Fontenla Santiago , Graham Jennie , Hall Christopher , Thompson Sam , Andrews Toby G. R. , Rawlinson Kate A. , Berriman Matthew , Rinaldi Gabriel
Published: March 2024

Schistosomiasis is a major Neglected Tropical Disease, caused by the infection with blood flukes in the genus Schistosoma. To complete the life cycle, the parasite undergoes asexual and sexual reproduction within an intermediate snail host and a definitive mammalian host, respectively. The intra-molluscan phase provides a critical amplification step that ensures a successful transmission. However, the cellular and molecular mechanisms underlying the development of the intra-molluscan stages remain poorly understood. Here, single cell suspensions from S. mansoni mother sporocysts were produced and sequenced using the droplet-based 10X Genomics Chromium platform. Six cell clusters comprising two tegument, muscle, neuron, parenchyma and stem/germinal cell clusters were identified and validated by in situ hybridisation. Gene Ontology term analysis predicted key biological processes for each of the clusters, including three stem/germinal sub-clusters. Furthermore, putative transcription factors predicted for stem/germinal and tegument clusters may play key roles during parasite development and interaction with the intermediate host.
Imaging predictors of hemorrhagic progression of a contusion after traumatic brain injury: a systematic review and meta-analysis
Authors: Peng Jie , Luo Tao , Li Xiaoyu , Li Bin , Cheng Yuan , Huang Qin , Su Jun
Published: March 2024

The hemorrhagic progression of a contusion (HPC) after Traumatic brain injury (TBI) is one of the important causes of death in trauma patients. The purpose of this meta-analysis was to evaluate the predictive effect of imaging features of Computed tomography (CT) on HPC after TBI. A comprehensive systematic search was performed using PubMed, EMBASE, and WEB OF SCIENCE databases to identify all relevant literature. A total of 8 studies involving 2543 patients were included in this meta-analysis. Meta-analysis showed that subarachnoid hemorrhage (OR 3.28; 95% CI 2.57–4.20), subdural hemorrhage (OR 4.35; 95% CI 3.29–5.75), epidural hemorrhage (OR 1.47;95% CI 1.15–1.89), contrast extravasation (OR 11.81; 95% CI 4.86–28.71) had a predictive effect on the occurrence of HPC. Skull fracture (OR 1.64; 95% CI 0.84–3.19) showed no statistical significance, and midline displacement > 5 mm (OR 4.66; 95% CI 1.87–11.62) showed high heterogeneity. The results of this meta-analysis showed that some imaging features were effective predictors of HPC after TBI. Well-designed prospective studies are needed to more accurately assess the effective predictors of HPC after TBI.
Application of machine learning algorithms for accurate determination of bilirubin level on in vitro engineered tissue phantom images
Authors: Yuan Yijia , Huang Jiayao , Yu Jiachen , Tan Justin Kok Soon , Chng Kevin Ziyang , Lee Jiun , Kim Sangho
Published: March 2024

Neonatal Jaundice is a common occurrence in neonates. High excess bilirubin would lead to hyperbilirubinemia, leading to irreversible adverse damage such as kernicterus. Therefore, it is necessary and important to monitor neonates’ bilirubin levels in real-time for immediate intervention. However, current screening protocols have their inherent limitations, necessitating more convenient measurements. In this proof-of-concept study, we evaluated the feasibility of using machine learning for the screening of hyperbilirubinemia in neonates from smartphone-acquired photographs. Different machine learning models were compared and evaluated to gain a better understanding of feature selection and model performance in bilirubin determination. An in vitro study was conducted with a bilirubin-containing tissue phantom to identify potential biological and environmental confounding factors. The findings of this study present a systematic characterization of the confounding effect of various factors through separate parametric tests. These tests uncover potential techniques in image pre-processing, highlighting important biological features (light scattering property and skin thickness) and external features (ISO, lighting conditions and white balance), which together contribute to robust model approaches for accurately determining bilirubin concentrations. By obtaining an accuracy of 0.848 in classification and 0.812 in regression, these findings indicate strong potential in aiding in the design of clinical studies using patient-derived images.
Data-driven autonomous operation of VOCs removal system
Authors: Kang Myeonginn , Han Jongmin , Kim Yangjoon , Kim Seongcheon , Kang Seokho
Published: March 2024

Removal of volatile organic compounds (VOCs) from the air has been an important issue in many industrial fields. Traditionally, the operation of VOCs removal systems has relied on fixed operating conditions determined by domain experts based on their expertise and intuition. In practice, this manual operation cannot respond immediately to changes in the system environment. To facilitate the autonomous operation of the system, the operating conditions should be optimized properly in real time to adapt to the changes in the system environment. Recently, optimization frameworks have been widely applied to real-world industrial systems across various domains using different approaches. The primary motivation for this study is the effective implementation of an optimization framework targeting a VOCs removal system. In this paper, we present a data-driven autonomous operation method for optimizing the operating conditions of a VOCs removal system to enhance the overall performance. An optimization problem is formulated with the decision variables denoting the parameters associated with the operating condition, the environmental variables representing the measurements for the system environment, the constraints specifying the control ranges of the parameters, and the objective function representing the system performance as determined by the operating conditions and environment. Using the previous operation data from the system, a neural network is trained to model the system performance as a function of the decision and environmental variables to approximate the objective function. For the current state of the system environment, the optimal operating condition is derived by solving the optimization problem. A case study of a targeted VOCs removal system demonstrates that the proposed method effectively optimizes the operating conditions for improved system performance without intervention from domain experts.
From instable directional switching to controlled unidirectional operation in a nonlinear fiber ring laser
Authors: Hartung Alexander , Arshad Muhammad Assad , Jäger Matthias
Published: March 2024

We investigate a new phenomenon, where a reciprocal fiber ring laser switches from bidirectional to unidirectional operation above a certain pump power threshold. Significant simplifications regarding earlier experiments are presented, which for the first time allow the identification of individual nonlinear effects. We highlight the unique role of stimulated Raman scattering in triggering unidirectional operation, and that additional conditions apply. The threshold is reduced from 30 to 3.8 W, which eases potential applications.
Association study of morpho-phenological traits in quinoa (Chenopodium quinoa Willd.) using SSR markers
Authors: Souri Laki Ebrahim , Rabiei Babak , Marashi Hassan , Jokarfard Vahid , Börner Andreas
Published: March 2024

In this study, the genetic and molecular diversity of 60 quinoa accessions was assessed using agronomically important traits related to grain yield as well as microsatellite (SSR) markers, and informative markers linked to the studied traits were identified using association study. The results showed that most of the studied traits had a relatively high diversity, but grain saponin and protein content showed the highest diversity. High diversity was also observed in all SSR markers, but KAAT023, KAAT027, KAAT036, and KCAA014 showed the highest values for most of the diversity indices and can be introduced as the informative markers to assess genetic diversity in quinoa. Population structure analysis showed that the studied population probably includes two subclusters, so that out of 60 quinoa accessions, 29 (48%) and 23 (38%) accessions were assigned to the first and second subclusters, respectively, and eight (13%) accessions were considered as the mixed genotypes. The study of the population structure using Structure software showed two possible subgroups (K = 2) in the studied population and the results of the bar plot confirmed it. Association study using the general linear model (GLM) and mixed linear model (MLM) identified the number of 35 and 32 significant marker-trait associations (MTAs) for the first year (2019) and 37 and 35 significant MTAs for the second year (2020), respectively. Among the significant MTAs identified for different traits, the highest number of significant MTAs were obtained for grain yield and 1000-grain weight with six and five MTAs, respectively.
The eukaryotic-like characteristics of small GTPase, roadblock and TRAPPC3 proteins from Asgard archaea
Authors: Tran Linh T. , Akıl Caner , Senju Yosuke , Robinson Robert C.
Published: March 2024

Membrane-enclosed organelles are defining features of eukaryotes in distinguishing these organisms from prokaryotes. Specification of distinct membranes is critical to assemble and maintain discrete compartments. Small GTPases and their regulators are the signaling molecules that drive membrane-modifying machineries to the desired location. These signaling molecules include Rab and Rag GTPases, roadblock and longin domain proteins, and TRAPPC3-like proteins. Here, we take a structural approach to assess the relatedness of these eukaryotic-like proteins in Asgard archaea, the closest known prokaryotic relatives to eukaryotes. We find that the Asgard archaea GTPase core domains closely resemble eukaryotic Rabs and Rags. Asgard archaea roadblock, longin and TRAPPC3 domain-containing proteins form dimers similar to those found in the eukaryotic TRAPP and Ragulator complexes. We conclude that the emergence of these protein architectures predated eukaryogenesis, however further adaptations occurred in proto-eukaryotes to allow these proteins to regulate distinct internal membranes.
TREM2 protects from atherosclerosis by limiting necrotic core formation
Authors: Piollet Marie , Porsch Florentina , Rizzo Giuseppe , Kapser Frederieke , Schulz Dirk J. J. , Kiss Máté G. , Schlepckow Kai , Morenas-Rodriguez Estrella , Sen Mustafa Orkun , Gropper Julius , Bandi Sourish Reddy , Schäfer Sarah , Krammer Tobias , Leipold Alexander M. , Hoke Matthias , Ozsvár-Kozma Mária , Beneš Hannah , Schillinger Martin , Minar Erich , Roesch Melanie , Göderle Laura , Hladik Anastasiya , Knapp Sylvia , Colonna Marco , Martini Rudolf , Saliba Antoine-Emmanuel , Haass Christian , Zernecke Alma , Binder Christoph J. , Cochain Clément
Published: March 2024

Atherosclerosis is a chronic disease of the vascular wall driven by lipid accumulation and inflammation in the intimal layer of arteries, and its main complications—myocardial infarction and stroke—are the leading cause of mortality worldwide1,2. Recent studies have identified triggering receptor expressed on myeloid cells 2 (TREM2), a lipid-sensing receptor regulating myeloid cell functions3, to be highly expressed in macrophage foam cells in experimental and human atherosclerosis4. However, the role of TREM2 in atherosclerosis is not fully known. Here we show that hematopoietic or global TREM2 deficiency increased, whereas TREM2 agonism decreased, necrotic core formation in early atherosclerosis. We demonstrate that TREM2 is essential for the efferocytosis capacities of macrophages and to the survival of lipid-laden macrophages, indicating a crucial role of TREM2 in maintaining the balance between foam cell death and clearance of dead cells in atherosclerotic lesions, thereby controlling plaque necrosis.
Key components of sustainable climate-smart ocean planning
Authors: Frazão Santos Catarina , Agardy Tundi , Crowder Larry B. , Day Jon C. , Pinsky Malin L. , Himes-Cornell Amber , Reimer Julie M. , García-Morales Sara , Bennett Nathan J. , Lombard Amanda T. , Calado Helena , Scherer Marinez , Flannery Wesley , Wedding Lisa M. , Gissi Elena
Published: March 2024

Planning of marine areas has spread widely over the past two decades to support sustainable ocean management and governance. However, to succeed in a changing ocean, marine spatial planning (MSP) must be ‘climate-smart’— integrating climate-related knowledge, being flexible to changing conditions, and supporting climate actions. While the need for climate-smart MSP has been globally recognized, at a practical level, marine managers and planners require further guidance on how to put it into action. Here, we suggest ten key components that, if well-integrated, would promote the development and implementation of sustainable, equitable, climate-smart MSP initiatives around the globe.
Metal-free functionalization of tyrosine residues in short peptides and study of the morphological alterations
Authors: Karmakar Santanu , Sukumar Genji , Prasanthkumar Seelam , Jha Babli K. , Mainkar Prathama S. , Nayani Kiranmai , Chandrasekhar Srivari
Published: March 2024

An efficient metal-free method for the conversion of tyrosine to 4-amino-3-methoxy phenylalanine or 4-amino phenylalanine has been developed in one pot via controlled oxidative dearomative functionalization.
Highly selective electroreduction of CO2 to CO with ZnO QDs/N-doped porous carbon catalysts
Authors: Fang Zijian , Zhai Yanling , Guo Weiwei , Sun Zhaoyang , Jiao Lei , Zhu Zhijun , Lu Xiaoquan , Tang Jianguo
Published: March 2024

ZnO quantum dots supported on porous nitrogen-doped carbon exhibit an excellent CO2RR performance, with the faradaic efficiency (CO) of 95.3% and a current density of 22.7 mA cm−2.
Chemodivergent mechanosynthesis of cyclopentenyl and pyrrolinyl spirobarbiturates from unsaturated barbiturates and enamino esters
Authors: Li Ming-Jun , Lu Ming-Ming , Xu Peng , Chen Si-Qi , Wu Luan-Ting , Zhang Ze , Xu Hui
Published: March 2024

A controllable spirocyclization of unsaturated barbiturates with enamines to selectively synthesize spirobarbiturates has been developed under ball-milling conditions.
Water-soluble chiral coordination polymers of Li+, Na+, K+, and Ba2+ with an anionic iron(iii) complex of a l-threonine derivative and a significant red shift of visible spectra with Al3+ salt
Authors: Long Chanreingam , Ray Manabendra
Published: March 2024

Four chiral water-soluble coordination polymers of an anionic iron(iii) bis-complex and metal cations were synthesized from water or methanol. The addition of Al3+ salt to Na+ complex showed an unexpected colour shift.
Re-utilization of drinking water treatment residuals (DWTR): a review focused on the adsorption of inorganic and organic contaminants in wastewater and soil
Authors: Belzile Nelson , Chen Yu-Wei
Published: March 2024

Drinking water treatment residuals (DWTRs) show versatile adsorption properties for the removal of contaminants from wastewater and soil. Most adsorption studies are based on synthetic well-controlled solutions instead of real wastewater samples.
Improvement of hepatic innate immunity in chemically-injured livers to develop hepatocarcinoma by a serine type-protease inhibitors enriched extract from Chenopodium quinoa
Authors: Rueda Huélamo Maria Alicia , Martínez Perlado Alba , Consoli Valeria , García-Tejedor Aurora , Haros Claudia Monika , Laparra Llopis José Moisés
Published: March 2024

SETIs ameliorate liver injury by promoting a selective polarization of hepatic macrophages and ILCs to influence the hepatic lipids profile.
Extraction, purification, structural modification, activities and application of polysaccharides from different parts of mulberry
Authors: Wang Huilin , Huang Gangliang
Published: March 2024

Extraction, purification, structural modification, activities and application of polysaccharides from different parts of mulberry were analyzed and discussed.
BODIPY-cucurbituril complexes: supramolecular approach toward improvement of photodynamic activity
Authors: Demuth Jiri , Kaushik Rahul , Kozlikova Magdalena , Rando Carola , Machacek Miloslav , Novakova Veronika , Šindelář Vladimír , Zimcik Petr
Published: March 2024

Host–guest interaction of cucurbit[7]uril with lipophilic bodipys decreases aggregation in water and improves photophysical properties and photodynamic activity upon activation.
4-Trifluoromethyl bithiazoles as broad-spectrum antimicrobial agents for virus-related bacterial infections or co-infections
Authors: Barbieri Francesca , Carlen Vincent , Martina Maria Grazia , Sannio Filomena , Cancade Sacha , Perini Cecilia , Restori Margherita , Crespan Emmanuele , Maga Giovanni , Docquier Jean-Denis , Cagno Valeria , Radi Marco
Published: March 2024

Is magic trifluoromethyl a thing? Replacing 4-CH3 with 4-CF3 in bithiazoles, allowed to identify broad antimicrobial agents active against multiple viruses and also against Gram-positive/negative bacteria.
Face-on-oriented formation of bis(diimino)metal coordination nanosheets on gold electrodes by electrochemical oxidation
Authors: Maeda Hiroaki , Takada Kenji , Fukui Naoya , Masunaga Hiroyasu , Sasaki Sono , Tsukagoshi Kazuhito , Nishihara Hiroshi
Published: March 2024

Bis(diimino)metal coordination nanosheets (MHABs) were successfully synthesized in a face-on orientation manner on gold electrodes using electrochemical oxidation methods under optimal reaction conditions.
Isostructural chiral metal–organic frameworks with metal-regulated performances for electrochemical enantiomeric recognition of tyrosine and tryptophan
Authors: An Ran , Hu Qiu-Yan , Song Liu-Yang , Zhang Xu , Li Rui-Xuan , Gao En-Qing , Yue Qi
Published: March 2024

Two isostructural homochiral MOFs exhibit significantly different enantioselective recognition performances closely associated with the different coordination habits of the metal centers in the MOFs.
Predicting valence tautomerism in diverse cobalt–dioxolene complexes: elucidation of the role of ligands and solvent
Authors: M. Zahir F. Zahra , Hay Moya A. , Janetzki Jett T. , Gable Robert W. , Goerigk Lars , Boskovic Colette
Published: March 2024

An inexpensive DFT-based strategy has been identified for the prediction of valence tautomerism in neutral and cationic Co–dioxolene complexes, including prediction of the interconversion temperature and variation with solvent.
A new insight into the chemical degradation of proton exchange membranes in water electrolyzers
Authors: Rui Zhiyan , Hua Kang , Dou Zhenlan , Tan Aidong , Zhang Chunyan , Shi Xiaoyun , Ding Rui , Li Xiaoke , Duan Xiao , Wu Yongkang , Zhang Yipeng , Wang Xuebin , Li Jia , Liu Jianguo
Published: March 2024

A new insight to interpret the PEM degradation process in both electrodes of a PEMWE.
Nanomaterial-based VOC sensing applications and a deep dive into their developmental trends
Authors: Rosario Warren , Singh Pravin Kumar , Tiwari Ashutosh , Jain Utkarsh , Avasthi Devesh Kumar , Chauhan Nidhi
Published: March 2024

Volatile organic compounds with their sources, key sensing applications and the different nanomaterial categories used for sensor fabrication.
Non-halogenated and non-volatile solid additive for improving the efficiency and stability of organic solar cells
Authors: Choi Mi , Jeong Hyeon-Seok , Lee Jinho , Choi Yeonsu , Kim In-Bok , Kim Dong-Yu , Kang Hongkyu , Jang Soo-Young
Published: March 2024

A non-halogenated and non-volatile solid additive PID can interact simultaneously with donor and acceptor molecules and stabilize the bulk-heterojunction morphology, increasing the efficiency and thermal stability of organic solar cell devices.
Solar-powered plasmon-boosted graphene towards enhanced ammonia production
Authors: Kaur Manpreet , Alagumalai Avinash , Sadri Rad , Tandon Saana , Osman Sameh M. , Roberts Edward P. L. , Song Hua
Published: March 2024

The urgent need for sustainable and efficient ammonia production has driven intense research towards alternative electrochemical routes.
Shedding light on ONOO− detection: the emergence of a fast-response fluorescent probe for biological systems
Authors: Wu Guoliang , Li Zihong , Huang Ping , Lin Weiying
Published: March 2024

ONOO−, a bioactive molecule, plays a critical role in inflammation-related signaling pathways and pathological mechanisms.
Photoinduced CO-releasing molecule (photoCORM) as an in situ CO surrogate for palladium-catalysed aminocarbonylation
Authors: Annereau Marcel , Salmain Michèle , Corcé Vincent
Published: March 2024

Herein, we show that a photoCORM behaves as an in situ CO surrogate, allowing the synthesis of variously functionalised amides including the biologically active compound Moclobemide by Pd-catalysed aminocarbonylation under mild conditions.
A zincophilic separator with directional alignment and pore hydrophilicity towards stable aqueous zinc metal batteries
Authors: Fu Jing , Huang Dongyang , Mei Ying , Ni Qiao
Published: March 2024

A low-cost and excellent mechanical property zincophilic separator (PZO) is developed by incorporating a Zn(OTF)2 salt into the PAN nanofibers.
A highly sensitive ratiometric fluorescence immunoassay based on bioorthogonal nanozymes
Authors: Liu Xiajian , Wang Nianhua , Hou Yixuan , Dong He , Liang Wenhua , Li Xinchun , Yuan Youyong
Published: March 2024

We designed a novel ratiometric fluorescence immunoassay based on bioorthogonal nanozymes for carcinoembryonic antigen detection.
Gefitinib salts/cocrystals with phenolic acids as a promising solid-state approach to improve solubility
Authors: Zou Yao , Meng Xin , Zhang Baoxi , Yu Hongmei , He Guorong , Gong Ningbo , Lu Yang , Du Guanhua
Published: March 2024

In this study, we designed and synthesized a series of gefitinib (GEF) salts and cocrystals with phenolic acids, comprising two salts, one cocrystal, and two salt cocrystals. All these forms exhibited significant improvements in solubility compared to pure GEF.
Picosecond quantum-classical dynamics reveals that the coexistence of light-induced microbial and animal chromophore rotary motion modulates the isomerization quantum yield of heliorhodopsin
Authors: Palombo Riccardo , Barneschi Leonardo , Pedraza-González Laura , Yang Xuchun , Olivucci Massimo
Published: March 2024

Rhodopsins are light-responsive proteins forming two vast and evolutionary distinct superfamilies whose functions are invariably triggered by the photoisomerization of a single retinal chromophore.
Exploring the carbonic anhydrase-mimetic [(PMDTA)2ZnII2(OH−)2]2+ for nitric oxide monooxygenation
Authors: Das Sandip , Kumar Pankaj
Published: March 2024

The reaction of ZnII-hydroxide (1) with NO showed the generation ZnII–nitrito complex (3) with H2 gas evolution via a proposed ZnII-nitrous acid intermediate.
Enantiodivergent biosynthesis of β-hydroxy esters by self-sufficient heterogeneous biocatalysts in a continuous flow
Authors: Andrés-Sanz Daniel , Maiz-Iginitz Ainhoa , Bolivar Juan M. , Orrego Alejandro H. , Sardon Haritz , López-Gallego Fernando
Published: March 2024

Developing two self-sufficient heterogeneous biocatalysts to synthesise enantiopure β-hydroxy esters in continuous flow. Operational conditions are tuned to maximise the productivity and stability of biocatalytic packed-bed reactors.
Microwave assisted batch and continuous flow Suzuki–Miyaura reactions in GVL using a Pd/PiNe biowaste-derived heterogeneous catalyst
Authors: Valentini Federica , Di Erasmo Benedetta , Ciani Marta , Chen Shaomin , Gu Yanlong , Vaccaro Luigi
Published: March 2024

Aiming at the development of low-impact synthetic pathways, we herein report the simultaneous employment of different tools to improve the overall sustainability of the Suzuki–Miyaura (SM) cross-coupling with a circular economy approach.
Protecting-group-free mechanosynthesis of amides from hydroxycarboxylic acids: application to the synthesis of imatinib
Authors: Nikonovich Tatsiana , Jarg Tatsiana , Martõnova Jevgenija , Kudrjašov Artjom , Merzhyievskyi Danylo , Kudrjašova Marina , Gallou Fabrice , Aav Riina , Kananovich Dzmitry
Published: March 2024

The mechanochemical protecting-group-free amidation of hydroxycarboxylic acids is presented. The transformation is applied to the synthesis of imatinib via a two-fold C–N bond construction sequence that bypasses a chlorinated genotoxic intermediate.
Photothermal properties of MXenes and sterilization of MRSA by Nb2C/Gel with a low power NIR-II laser
Authors: Zheng Yekai , Fu Xinyi , Jiang Li , Li Denghao , Zhao Weidan , Liu Mi , Liu Jiali , Jin Shangzhong , Zhou Yan
Published: March 2024

A comparative study on the photothermal properties of MXenes (Ti3C2, V2C and Nb2C) and MXene/Gels (Ti3C2/Gel, V2C/Gel and Nb2C/Gel). The fast and efficient sterilization of MRSA was achieved using Nb2C/Gel at low laser power.
Deciphering the mechanistic insights of 4-nitrophenol reduction catalyzed by a 1D–2D Bi2S3 nanostructured catalyst
Authors: Mahto Bhagirath , Barhoi Ashok , Ali Haider , Hussain Sahid
Published: March 2024

An anisotropic 1D-2D Bi2S3 nanostructured catalyst is developed for 4-nitrophenol (4-NP) reduction and highlighted the critical roles of water as proton source and adsorbed/absorbed hydrogen species on the catalyst surface in 4-NP reduction.
Development of hybrid electrospun alginate-pulverized moringa composites
Authors: Orisawayi Abimbola Oluwatayo , Koziol Krzysztof , Hao Shuai , Tiwari Shivam , Rahatekar Sameer S.
Published: March 2024

The consideration of biopolymers with natural products offers promising and effective materials with intrinsic and extrinsic properties that are utilized in several applications.
The dual-model up/down-conversion green luminescence of NaSrGd(MoO4)3: Er3+ and its application for temperature sensing
Authors: El Abidine Aly Taleb Zein , Saidi Kamel , Dammak Mohamed
Published: March 2024

Intense green up/down conversion emission and high-sensitivity optical thermometry.
4-Fluorobenzyl cyanide, a sterically-hindered solvent expediting interfacial kinetics in lithium-ion batteries
Authors: Qin Mingsheng , Zeng Ziqi , Wu Qiang , Liu Xiaowei , Liu Qijun , Cheng Shijie , Xie Jia
Published: March 2024

4-Fluorobenzyl cyanide, combining a bulky substituent and deactivated Lewis basic center, is designed to formulate an EC-free electrolyte, which exhibits wide-liquid range, high safety level and good rate capability in lithium-ion batteries.
Efficient red thermally activated delayed fluorescence emitters achieved through precise control of excited state energy levels
Authors: Zhang BoHua , Liu SiQi , Pei JiangXue , Luo MeiTing , Chen Yi , Jia QingYu , Wu ZhaoXin , Wang DongDong
Published: March 2024

By adjusting the excited state energy levels to design deep-red TADF emitters, providing a powerful means for rapidly screening efficient emitters in the future.
Combining total synthesis and genetic engineering to probe dihydropyran formation in ambruticin biosynthesis
Authors: Bowen James I. , Zhong Xiaotong , Gao Kaining , Reed Benjamin , Crump Matthew P. , Wang Luoyi , Willis Christine L.
Published: March 2024

Integrating total synthesis with genetic engineering of Sorangium strains reveal insights into the enzyme-catalysed formation of the 20,21-alkene in ambruticin biosynthesis.
Ionic liquid strategy for chitosan production from chitin and molecular insights
Authors: Dinh Van Minh , Khokarale Santosh Govind , May Pedro Ojeda , Sparrman Tobias , Irgum Knut , Mikkola Jyri-Pekka
Published: March 2024

Chitosan production from [Emim][OAc] IL-pretreatment of shrimp chitin and subsequent microwave-mediated deacetylation is described. [Emim][OAc] and [TBA][OH] can be recovered. MD simulation of the [TBA][OH]–chitin system is illustrated.
Two-step cold sintering of Li1.3Al0.3Ti1.7(PO4)3 composite solid electrolyte with non-equilibrium microstructures for enhanced electrochemical performance
Authors: Jiao Jiabin , Xie Ziqian , Zhang Yangdong , Zhao Chunlin , Wu Xiao , Lin Tengfei , Gao Min , Lin Cong
Published: March 2024

High densification and high electrochemical performance were obtained in solid-state electrolytes with non-equilibrium microstructures by two-step cold sintering.
Coupling electrocatalytic redox-active sites in a three-dimensional bimetalloporphyrin-based covalent organic framework for enhancing carbon dioxide reduction and oxygen evolution
Authors: Li Jie , Tan Yan-Xi , Lin Jing , Feng Yangyang , Zhang Xiang , Zhou Enbo , Yuan Daqiang , Wang Yaobing
Published: March 2024

The 3D Co/Ni–TPNB-COF couples redox-active sites due to the charge redistribution between Ni(ii)-porphyrin and Co(ii)-porphyrin, and further simultaneously enhances its electrocatalytic carbon dioxide reduction and oxygen evolution performances.
Selectivity in the chiral self-assembly of nucleobase-arylazopyrazole photoswitches along DNA templates
Authors: Nogal Noemí , Guisán Santiago , Dellemme David , Surin Mathieu , de la Escosura Andrés
Published: March 2024

The photoswitching behaviour of arylazopyrazole derivatives modified with nucleobases controls their self-assembly process along oligomeric DNA templates, opening the way to potential applications as nano- and biomaterials.
A Novel Security Scheme Supported by Certificateless Digital Signature and Blockchain in Named Data Networking
Authors: Li Bing , Zheng Mingxuan , Ma Maode
Published: March 2024

Named Data Networking (NDN) is a promising network architecture that differs from the traditional TCP/IP network, as it focuses on data rather than the host. A new secure model is required to provide the data‐oriented trust instead of the host‐oriented trust. This paper proposes a new secure solution in the NDNs named Secure Mechanism supported by Certificateless Digital Signature and Blockchain (CLDS‐B). The CLDS‐B scheme employs a certificateless digital signature to guarantee the authentication and integrity of data. On the one hand, the key escrow problem has been solved to eliminate the risks of compromised private key generators; on the other hand, the data name has been bound to the public key to prevent the false public key. Moreover, the blockchain is used to manage cryptographic information. Each domain designates an information service entity to join the blockchain so that the consumer could retrieve the cryptographic information public parameter in the local domain if necessary. Furthermore, due to the decentralization of the blockchain, the CLDS‐B would be robust to resist the single‐node failure. Simulation results show that the CLDS‐B scheme outperforms a classic NDN scheme, although it shows slightly inferior to the other secure NDN scheme. The security verification and analysis show that the CLDS‐B would resist the key escrow attack. The CLDS‐B would be a competitive solution in scenarios with a high‐security level.
A person re‐identification method for sports event scenes incorporating textual information mining
Authors: Wang Runmin , Zhu Yanbin , Wan Zukun , Chen Hua , Zhu Zhenlin , Zhou Weixin , Han Chang , Ding Yajun
Published: March 2024

Person re‐identification represents a pivotal sub‐problem in image retrieval, boasting broad application prospects in fields such as intelligent security and video surveillance. However, most existing person re‐identification methods predominantly focus solely on visual features pertaining to the person targets, thereby disregarding some supporting information closely related to the scene context. In the context of athlete re‐identification during sports event scenes, the athlete bib number is fully considered, an important clue that can provide different athletes' identities, and the traditional visual features of the person and high‐level semantic information of the bib number text are fused. A multi‐source information mutual gain mechanism is designed to improve the accuracy of the person re‐identification task. In the existing only publicly available marathon bib number dataset RBNR, the recognition accuracy of this method is significantly superior to that of the existing person re‐identification method. In addition, this paper constructs and publishes an athlete re‐identification dataset (HNNU‐ReID8000) for mainstream sports events, and the mean average precision (mAP) value of this method reaches 96.1% on this dataset, significantly ahead of existing state‐of‐the‐art person re‐identification methods. The code and the HNNU‐ReID8000 dataset will be released at https://github.com/yanbin‐zhu/zyb_person‐reid.
A multidimensional fusion image stereo matching algorithm
Authors: Quan Zhenhua , Luo Liang , Wu Bin
Published: March 2024

In response to the low matching accuracy of stereo matching algorithms in image regions with specular reflection, this paper proposes a multidimensional fusion stereo matching algorithm named MFANet. The algorithm embeds a multispectral attention module into the residual feature extraction network, utilizing two‐dimensional discrete cosine transforms to extract frequency features. In the pyramid pooling module, a coordinated attention mechanism is introduced to capture relevant positional information. In the cost aggregation part, the MFANet algorithm incorporates a three‐dimensional attention mechanism, focusing on the more important semantic information in high‐level features. By combining detailed information from low‐level features, semantic information from high‐level features, and contextual information, the algorithm generates features that are more conducive to disparity prediction. The MFANet algorithm is evaluated on three standard datasets (SceneFlow, KITTI2015, and KITTI2012). Experimental results demonstrate its robustness against specular reflection interference, accurate prediction of disparities in specular reflection pathological regions, and promising application prospects.
Bleaching of red clay using Na2S2O4 and NaBH4 in acidic solution
Authors: Hoa Bui Thi , Phuc Le Hong , Hien Nguyen Quan , Quynh Nguyen Thi Nhat , Thanh Dao Hiep , Nhat Tran Tan , Vuong Bui Xuan
Published: March 2024

Bleaching of red clay is carried out by reacting iron-containing clay with the system of two reducing agents Na2S2O4, and NaBH4, in an acidic environment. The treatment process is performed with the help of ultrasonic equipment, as well as mixing operations performed at high temperature. Several physical-chemical methods such as XRF, XRD, and FTIR were used to evaluate clay samples before and after treatment. The results showed effective iron-removal in red clay. Comparison of whiteness between the processed sample and the original sample is performed by measuring parameters in the CIE L*a*b* color-system. The analysis shows that the whiteness of the treated sample reached 78.72%, showing that the treated clay has clearly improved its whiteness, and can be applied in making high-end ceramic products that require the clay with high whiteness.
Cladocera (Crustacea; Branchiopoda) from the Brazilian Cerrado – the richness and species composition for Goiás state
Authors: Carvalho Vinícius Vilela , Elmoor-Loureiro Lourdes M.A. , Sousa Francisco Diogo R.
Published: March 2024

Goiás state, situated in the Cerrado biome harbors several water bodies belonging to the Paraná, São Francisco, and Tocantins-Araguaia hydrographic regions. However, there are several gaps in the knowledge about the diversity and geographic distribution of aquatic invertebrates in the state, including microcrustaceans of the Superorder Cladocera. Thus, this study aims to elaborate an updated list of cladoceran species occurring in Goiás, using data from 37 literature sources and original samples from different ecosystems and localities. The history and type of publications were evaluated. The number of studies between 1988 and 2022 and the type of publications and species richness were listed. The literature data indicated that most studies reporting or describing species for Goiás were found in papers published in indexed journals (75%). Tocantins-Araguaia was the hydrographic region with the highest number of studies (20). The number of observed species was strongly related to the number of studies (r2 = 0.59; p < 0.0001). When observing literature data and findings from sampling, 92 species were recorded with five news reports: Scapholeberis freyi, Grimaldina freyi, Parvalona parva, Chydorus brevilabris, and Picripleuroxus quasidenticulatus. The number and composition of species in Goiás state should be considered relevant. However, the observed richness is lower than expected (114 spp), suggesting the need for increased sampling effort. The focus of this sampling should preferably occur in areas lacking information.
A sustainable manufacturing–remanufacturing inventory model with price and green sensitive demand for defective and usable items
Authors: Haque Rakibul , Pervin Magfura , Mondal Sankar Prasad
Published: March 2024

A sustainable manufacturing–remanufacturing inventory model with two production phases is presented in this study. In this two phases model, the first phase is used for manufacturing whereas the second phase is used for both manufacturing and remanufacturing. Keeping in mind about environment and price of products, it is presumed that market demand rate is influenced by the greenness of item and unit selling price simultaneously. Remanufacturing is performed for non-serviceable items i.e., defective items which are produced from imperfect production and used items that are purchased from the market. But the products for which remanufacturing cost is more than manufacturing cost are scraped off. In the production process carbon releases from setting up, manufacture and holding of the perfect items. To mitigate the carbon emission carbon tax regulation is imposed. Next, concavity of the profit function is driven through the pseudo concavity. Profit is maximized by minimizing the economic, environmental, and social effect. The models are illustrated by a numerical example and a sensitivity analysis is also elaborated for fixed parameters. Special cases are provided to compare the result with previous literature. The results shows that manufacturer wishes to engage in remanufacturing as remanufacturing cost continuously increases with respect time. Another important finding is that the manufacturer can choose remanufacturing as the cost is lower than manufacturing for saving environment. Finally, mathematical findings are listed and managerial implications are recorded.
Beatmungsspezifische Hilfsmittelversorgung – bedarfsgerecht und
sicher?
Authors: Lehmann Yvonne , Stark Susanne
Published: March 2024

Einleitung Für häuslich beatmete Patient*innen ist die Versorgung mit
Hilfsmitteln essenziell. Dabei ist weitgehend unklar, wie bedarfsgerecht und
sicher diese Versorgung ist.

Methodik Innerhalb eines Versorgungsforschungsprojekts wurden 20
Experteninterviews mit einer heterogenen Gruppe von Akteur*innen mit Bezug zur
beatmungsspezifischen Hilfsmittelversorgung geführt und
qualitativ-inhaltsanalytisch ausgewertet.

Ergebnisse Deutlich werden Herausforderungen und Probleme hinsichtlich
struktureller, prozessualer und personaler Aspekte auf allen Ebenen der
Versorgung. Besondere Defizite bestehen in der Aufgabenwahrnehmung, Koordination
und Kooperation der beteiligten Akteur*innen und Instanzen. Sie gehen mit
vermeidbaren Sicherheitsrisiken einher und stehen einer bedarfsgerechten
Hilfsmittelversorgung im Wege.

Schlussfolgerung Es bestehen Entwicklungsbedarfe in der HM-Versorgung
häuslich beatmeter Patient*innen, vor allem in Richtung einer evidenzbasierten
Weiterentwicklung, einer flächendeckenden, sektoren- und
professionsübergreifenden Ausgestaltung sowie einer systematischen
Evaluation.
Implications of Online Self-Diagnosis in Psychiatry
Authors: Monteith Scott , Glenn Tasha , Geddes John R. , Whybrow Peter C. , Achtyes Eric D. , Bauer Michael
Published: March 2024

Online self-diagnosis of psychiatric disorders by the general public is
increasing. The reasons for the increase include the expansion of Internet
technologies and the use of social media, the rapid growth of direct-to-consumer
e-commerce in healthcare, and the increased emphasis on patient involvement in
decision making. The publicity given to artificial intelligence (AI) has also
contributed to the increased use of online screening tools by the general
public. This paper aims to review factors contributing to the expansion of
online self-diagnosis by the general public, and discuss both the risks and
benefits of online self-diagnosis of psychiatric disorders. A narrative review
was performed with examples obtained from the scientific literature and
commercial articles written for the general public. Online self-diagnosis of
psychiatric disorders is growing rapidly. Some people with a positive result on
a screening tool will seek professional help. However, there are many potential
risks for patients who self-diagnose, including an incorrect or dangerous
diagnosis, increased patient anxiety about the diagnosis, obtaining unfiltered
advice on social media, using the self-diagnosis to self-treat, including online
purchase of medications without a prescription, and technical issues including
the loss of privacy. Physicians need to be aware of the increase in
self-diagnosis by the general public and the potential risks, both medical and
technical. Psychiatrists must recognize that the general public is often unaware
of the challenging medical and technical issues involved in the diagnosis of a
mental disorder, and be ready to treat patients who have already obtained an
online self-diagnosis.
Low-dose pulsed vs standard pulsed fluoroscopy during ERCP to reduce radiation without change in image quality: Prospective randomized study
Authors: Ali Osman , Kesar Varun , Alizadeh Madeline , Kalachi Kourosh , Twery Benjamin , Wellnitz Nicholas , Kim Raymond Eunho , Goldberg Eric , Uradomo Lance T , Darwin Peter E
Published: March 2024

Background and study aims Endoscopic retrograde cholangiopancreatography (ERCP) poses the risk of radiation exposure (RE) to patients and staff and increases the risk of adverse biological effects such as cataracts, sterility, and cancer. Newer fluoroscopy equipment (C-Arm) provides options to limit radiation in the form of lower radiation dose and frame rate or time-limited “pulsed” settings. However, the impact of lower settings on image quality has not been assessed, and no standard protocol exists for fluoroscopy settings used during ERCP.

Patients and methods This was a single-center, double-blind, prospective randomized study of consecutive adult patients undergoing standard-of-care ERCP at a tertiary academic medical center. Patients were randomized into two groups: 1) standard-dose pulsed and 2) low-dose pulsed. Pulsed mode (8 fps) was defined as x-ray exposure either in the manufacturer standard-dose or low-dose settings limited to 3 seconds each time the foot-operated switch was depressed.

Results Seventy-eight patients undergoing ERCP were enrolled and randomized. No difference in age, gender, or body mass index was found between the two groups. No significant difference in image quality was found between standard-dose and low-dose fluoroscopy P = 0.925). The low-dose group was exposed to significantly less radiation when compared with standard-dose P < 0.05). Fluoroscopy time (minutes) was similar in both groups (2.0 vs 1.9), further suggesting that group assignment had no impact on image quality or procedure time.

Conclusions Low-dose pulsed fluoroscopy is a reliable method that substantially reduces radiation without compromising image quality or affecting procedure or fluoroscopy times. This underscores the need for standardization in ERCP fluoroscopy settings to limit radiation exposure.
Efficacy and safety of the water pressure method for endoscopic submucosal dissection in superficial pharyngeal cancer
Authors: Matsuura Noriko , Kato Motohiko , Iwata Kentaro , Miyazaki Kurato , Masunaga Teppei , Kubosawa Yoko , Mizutani Mari , Hayashi Yukie , Sasaki Motoki , Sujino Tomohisa , Takabayashi Kaoru , Akimoto Teppei , Takatori Yusaku , Nakayama Atsushi , Sekimizu Mariko , Ozawa Hiroyuki , Yahagi Naohisa
Published: March 2024

Background and study aims Superficial pharyngeal cancers can be cured with transoral surgery (TOS), which preserves organ function and quality of life. Pharyngeal endoscopic submucosal dissection (ESD) is challenging to perform because of limited maneuverability and complex anatomical features. The water pressure method (WPM) is useful for natural traction techniques during ESD and is potentially useful for pharyngeal ESD. This study aimed to investigate the short-term outcomes of WPM-ESD for pharyngeal lesions.

Patients and methods Therapeutic outcomes of patients who underwent WPM-ESD for pharyngeal lesions at Keio University between May 2019 and February 2022 were retrospectively analyzed.

Results Twenty-one pharyngeal lesions treated with WPM-ESD were analyzed. Three lesions were located in the oropharynx and 18 in the hypopharynx. All ESD procedures were performed under general anesthesia. The endoscopic en bloc resection rate was 100%. The median procedure time was 15 minutes (range 4–45 minutes). All patients were successfully extubated on the day of ESD. No serious adverse events (AEs) related to WPM-ESDs were observed. None of the patients required nasogastric intubation, percutaneous endoscopic gastrostomy, or tracheotomy. The median fasting time and hospital stay were 2 days (range 2–5 days) and 6 days (range 6–10 days), respectively. All the histological results indicated squamous cell carcinoma. The complete histologic resection rate was 76.2%.

Conclusions WPM-ESD achieved a high en bloc resection rate and short procedure time without serious AEs. Thus, it may be a useful treatment for pharyngeal lesions.
Potential for expanded application of endoscopic hand suturing: A pilot study of 15 cases
Authors: Higuchi Kazutoshi , Goto Osamu , Koizumi Eriko , Nakagome Shun , Habu Tsugumi , Ishikawa Yumiko , Kirita Kumiko , Noda Hiroto , Onda Takeshi , Omori Jun , Akimoto Naohiko , Iwakiri Katsuhiko
Published: March 2024

Endoscopic hand suturing (EHS) was first developed to firmly close a mucosal defect following endoscopic submucosal dissection and has the potential for expanded applications. This study aimed to investigate the feasibility and safety of EHS in various clinical settings. In this single-center pilot study, 15 patients who had diseases with potential indications for EHS were prospectively recruited. Technical success, clinical success after the procedure, and severe EHS-related adverse events (AEs) were evaluated. EHS was applied for defect closure after gastric subepithelial lesion removal under laparoscopic observation (n = 9), defect closure after rectal endoscopic full-thickness resection (EFTR) (n = 2), defect closure after thoracoscopy-assisted esophageal EFTR (n = 1), mucosal closure for gastric ulcer bleeding (n = 1), mucosal closure after peroral endoscopic myotomy (POEM) (n = 1), and postoperative anastomotic leak (n = 1). EHS was completed without severe AEs and the clinical courses were also favorable in 13 patients (87%). The median suturing time was 61 minutes. In patients with POEM and anastomotic leak, EHS was discontinued because of the narrow lumen. In conclusion, EHS appears feasible and safe in situations.