bluuebunny/crossref_metadata_2025 huggingface dataset:
The Texts of A Critical Exposition of the Philosophy of Leibniz
Authors: Blackwell Kenneth , Griffin Nicholas
Published: August 2017

The extant manuscript is described in relation to Russell’s Trinity College lecture course in 1899 and its subsequent preparation for the book of 1900. Alterations within the MS are reported. So are revisions that must have followed on a missing typescript, as derived from comparing G. E. Moore’s copy of the page proofs with the MS. His suggested changes are compared with the text of the first edition along with emendations Russell must have made on his own copy of the proofs.
Adrenocortical carcinoma and succinate dehydrogenase gene mutations: an observational case series
Authors: Else Tobias , Lerario Antonio Marcondes , Everett Jessica , Haymon Lori , Wham Deborah , Mullane Michael , Wilson Tremika LeShan , Rainville Irene , Rana Huma , Worth Andrew J , Snyder Nathaniel W , Blair Ian A , McKay Rana , Kilbridge Kerry , Hammer Gary , Barletta Justine , Vaidya Anand
Published: August 2017

Objective

Germline loss-of-function mutations in succinate dehydrogenase (SDHx) genes results in rare tumor syndromes that include pheochromocytoma, paraganglioma, and others. Here we report a case series of patients with adrenocortical carcinoma (ACC) that harbor SDHx mutations.

Patients and results

We report four unrelated patients with ACC and SDHx mutations. All cases presented with Cushing syndrome and large adrenal masses that were confirmed to be ACC on pathology. All four ACC specimens were found to have truncating mutations in either SDHC or SDHA, while cases 1, 2 and 3 also had the mutations confirmed in the germline: Case 1: SDHC c.397C > T, pR133X; Case 2: SDHC c.43C > T, p.R15X; Case 3: SDHA c.91C > T, p.R31X; Case 4: SDHA c.1258C > T, p.Q420X. Notably, Case 1 had a father and daughter who both harbored the same SDHC germline mutation, and the father had a paraganglioma and renal cell carcinoma. A combination of next generation sequencing, and/or immunohistochemistry, and/or mass spectroscopy was used to determine whether there was loss of heterozygosity and/or loss of SDH protein expression or function within the ACC. Potential evidence of loss of heterozygosity was observed only in Case 2.

Conclusions

We observed truncating mutations in SDHA or SDHC in the ACC and/or germline of four unrelated patients. Given how statistically improbable the concurrence of ACC and pathogenic germline SDHx mutations is expected to be, these observations raise the question whether ACC may be a rare manifestation of SDHx mutation syndromes. Further studies are needed to investigate the possible role of SDH deficiency in ACC pathogenesis.
A syndromic extreme insulin resistance caused by biallelic POC1A mutations in exon 10
Authors: Giorgio Elisa , Rubino Elisa , Bruselles Alessandro , Pizzi Simone , Rainero Innocenzo , Duca Sergio , Sirchia Fabio , Pasini Barbara , Tartaglia Marco , Brusco Alfredo
Published: August 2017

POC1A encodes a protein with a role in centriole assembly and stability, and in ciliogenesis. Biallelic loss-of-function mutations affecting POC1A cause SOFT syndrome, an ultra-rare condition characterized by short stature, onychodysplasia, facial dysmorphism and hypotrichosis. Using exome sequencing, we identified a homozygous frameshift mutation (c.1047_1048dupC; p.G337Rfs*25) in a patient presenting with short stature, facial hirsutism, alopecia, dyslipidemia and extreme insulin resistance. The truncating variant affected exon 10, which is retained in only two of the three POC1A-mature RNAs, due to alternative processing of the transcript. Clinical discrepancies with SOFT syndrome support the hypothesis that POC1A mutations affecting exon 10 are associated with a distinct condition, corroborating a previous hypothesis based on a similar case. Furthermore, this report provides an additional example of a genetic condition presenting with clinical heterogeneity due to alternative transcript processing. In conclusion, POC1A mutations in exon 10 should be taken into account in patients with extreme insulin resistance and short stature.
Scaphosepalum zieglerae, a showy new species in the genus (Pleurothallidinae: Orchidaceae)
Authors: Baquero R. Luis E.
Published: August 2017

Scaphosepalum zieglerae is described from a small area near Chical in northern Ecuador. It is distinguished by the large plant, waxy yellow flowers densely spotted with brown red to blood-red, spiky tails of the lateral sepals and a dark blood-red, wingless lip. It is here compared to Scaphosepalum beluosum with which it shares most similarities, and to S. fimbriatum, another species with fimbriated sepaline tails.
The application of whole-body vibration in physiotherapy – A narrative review
Authors: Stania M , Juras G , Słomka K , Chmielewska D , Król P
Published: August 2017

Whole-body vibration (WBV) training is a very popular kind of practice in sport, fitness and physiotherapy. This work reviews the current knowledge regarding the use and effectiveness of WBV in the physiotherapy. The discrepancies between different authors’ results are probably due to divergence in WBV training protocols. The paperwork clearly showed that despite its ultimate effects, exercises on a vibration platform are safe, feasible, and well tolerated by patients with different disorders. This narrative review should help physiotherapists verify therapy programs regarding patients’ exposure to WBV.
Efficacy of Rhus coriaria (sumac) juice in reducing muscle pain during aerobic exercise
Authors: Alghadir AH , Gabr SA
Published: August 2017

The main target of this study was to measure the influence of sumac juice drink on muscle indices and pain during an acute, intense exercise for 30 days. Forty healthy volunteers (15–25 years) were involved in aerobic exercise program for 4 weeks. Participants ingested sumac juice or placebo drink twice daily for 30 days. All participants were subjected for the evaluation of pain and estimation of serum: creatine kinase (CK), lactic acid dehydrogenase (LDH), troponin I, hydroxyproline (hyp), total antioxidant capacity (TAC), and in vitro antioxidant activity of sumac juice using pre-validated visual analog scale, colorimetric and immunoassays. The participants of both groups, placebo and sumac, showed an increment in pain scores both during exercise and post-exercise intervals. However, the sumac juice group showed a significant smaller increase in the pain scores compared to the placebo group. Participants in the sumac juice group were more willing to use the drink in the future. They achieved a higher satisfaction of sumac juice in ameliorating and the reduction of pain. Also, the sumac group showed a significant enhancement in the level of CK, LDH, troponin I, hyp, along with significant increase in serum (TAC) compared to the placebo group. The protective activity of muscle may relate to the antioxidant activity of phenolic component(s) in sumac juice as measured by 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging (87.9%) and β-carotene–linoleic acid (68.7%) assays. These data suggest that oral administration of sumac juice may have a beneficial effect on muscle performance among athletes.
Alterations of store-operated calcium entry and cyclopiazonic acid-induced endothelium-derived relaxations in aging rat thoracic aorta
Authors: Erac Y , Selli C , Tosun M
Published: August 2017

The purpose of our study was to investigate whether endothelium-derived relaxations induced by store depletion are altered in aging rat thoracic aorta. Vascular responses were measured in aortic segments isolated from young (2–4 month) and old (20–24 month) male Sprague-Dawley rats. In phenylephrine-contracted intact tissues, receptor-mediated and receptor-independent endothelium-derived relaxations were induced by acetylcholine (ACh) and sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA) blocker cyclopiazonic acid (CPA), respectively. In addition, CPA-induced changes in intracellular calcium levels were monitored in fura-2-loaded endothelium-denuded tissues. Real-time quantitative reverse transcription polymerase chain reaction and western blot analysis were performed to determine the transient receptor potential canonical (TRPC) 4 mRNA and protein levels. Endothelial TRPC4 mRNA levels were apparently decreased in aging rats. Immunoblot analysis showed that TRPC4 protein levels significantly decreased in intact aorta from 20- to 24-month-old rats compared to that from 2- to 4-month-old rats. ACh- and CPA-induced endothelium-dependent relaxations decreased in old rat aorta without any change in direct vasodilation induced by sodium nitroprusside. Store-operated Ca2+ entry (SOCE) induced by CPA was significantly decreased, whereas sarcoplasmic reticulum Ca2+ release was unaffected in endothelium-denuded aging rat aorta. In conclusion, TRPC4 downregulation could be associated with decreased endothelium-dependent vasorelaxations. As endothelial nitric oxide synthase is activated by SOCE-induced caveolar internalization, tracking the expression levels of SERCA, ion channels, and/or associated proteins involved in SOCE would lead to the development of novel therapeutics for age-related vasospastic disorders with dysfunctional endothelium.
Effect of pectin feeding on obesity development and duodenal alkaline phosphatase activity in Sprague-Dawley rats fed with high-fat/high-energy diet
Authors: Šefčíková Z , Raček L
Published: August 2017

Purpose

The objective of this study was to evaluate whether pectin feeding would affect the small intestinal function and whether these changes would lead to obesity prevention in rats fed with high-fat diet. Three groups of weaned male rats (ad lib. fed; rats fed with diet containing 15% w/w of citrus pectin; restrictedly pair-fed rats) were fed with either a standard diet (9.5% fat) or a high-fat diet (30% fat) for 10 days.

Results

Our results revealed that pectin feeding led to significant decreases in body weight, energy intake and fat pad weight in rats fed with the standard as well as high-fat diet. Moreover, compared to the restrictedly pair-fed rats, in both groups of rats fed with the diet containing pectin, significant decrease in duodenal alkaline phosphatase (AP) activity was observed in histochemically stained cryostat sections. In contrast, despite their lower energy intake, restrictedly pair-fed rats showed similar fat pad deposition accompanied by unchanged values of AP activity in comparison to the controls.

Conclusions

Our findings indicate that daily pectin consumption could be beneficial in suppressing body weight gain and reducing probability of obesity risk in rats fed with a high-fat diet.
Assessment of exhaled carbon monoxide in exacerbations of chronic obstructive pulmonary disease
Authors: Antus B , Drozdovszky O , Barta I
Published: August 2017

Introduction

Exhaled carbon monoxide (eCO) has been widely implicated as a pulmonary biomarker in respiratory diseases. The aim of this study was to investigate whether the treatment of patients with severe acute exacerbation of chronic obstructive pulmonary disease (AECOPD) could be aided by monitoring the changes in eCO.

Methods

The levels of eCO along with routine clinical parameters were analyzed in 29 current smoker and 33 ex-smoker COPD patients, first at the time of hospital admission, and again at discharge following the standard treatment. Patients with AECOPD were also stratified according to sputum bacteria.

Results

At exacerbation, the levels of eCO were increased in current smokers compared to ex-smokers (6.0 [2.0–9.5] versus 1.0 [1.0–2.0] ppm, p < 0.001). Similarly, eCO levels were higher in smokers after treatment (7.0 [2.0–12.5] versus 1.0 [1.0–2.0] ppm, p < 0.001). Treatment of AECOPD did not affect eCO concentrations. The levels of eCO were not statistically different between bacterial and non-bacterial AECOPD either. Investigating a subgroup of current smoker patients (n = 15), there was a significant correlation between the levels of eCO and blood carboxyhemoglobin concentrations both at exacerbation and discharge. No associations were found between eCO and lung function or blood gas parameters.

Conclusion

Our results suggest that monitoring eCO during the treatment of AECOPD is of limited clinical value.
Conversa com o Editor
Authors: Higuet Etienne Alfred
Published: August 2017

editor
Paul Tillich em diálogo com o Budismo Amidista Japonês: novas questões
Authors: Tada Elton Vinicius Sadao
Published: August 2017

o presente artigo tem como intenção colocar em diálogo a teologia de Paul Tillich com o Budismo Amidista japonês. O próprio Paul Tillich iniciou esse diálogo em sua visita ao Japão em 1960, mas deixou várias questões a serem respondidas. A partir desse passo inicial tentaremos propor um diálogo pormenorizado, tendo como centro a preocupação sobre a questão da salvação no Budismo Amidista japonês e sua validade em relação ao pensamento tillichiano.
Apresentação do dossiê
Authors: Higuet Etienne Alfred
Published: August 2017

dossiê religião e artes visuais
A fé que oprime em Ingmar Bergman: Considerações a partir de “Luz de Inverno” e “O Sétimo Selo”
Authors: Lopes Marques José Da Cruz
Published: August 2017

O presente artigo tenciona propor um diálogo entre teologia e cinema, tendo como fio condutor a temática da fé e suas possíveis relações à luz da doutrina cristã. Para este fim, a discussão será conduzida a partir de dois filmes que aprofundam a problemática da fé. A visão de uma fé que oprime, angustia e desespera em virtude de seu caráter paradoxal e absurdo será discutida a partir dos filmes Luz de inverno e O sétimo selo do cineasta sueco Ingmar Bergman. Eventualmente, recorreremos a categorias da filosofia kierkegaardiana a fim de lançar luz ao entendimento apresentado por Bergman nos filme supracitados.
Os desafios da Teologia Latino-Americana diante do contemporâneo
Authors: Gonçalves Alonso S.
Published: August 2017

RIBEIRO, Claudio de Oliveira. Testemunho e libertação: a teologia latino-americana em questão. São Paulo: Fonte Editorial, 2016, 162p.
Core Surgical Training – Taking Control
Authors: Jones Richard
Published: August 2017

This article was migrated. The article was marked as recommended. IntroductionToo often we look to others to improve or make changes to our training, but often, if as trainees we take responsibility for our training we can improve our own outcomes. This highlights a change I made to my rota and training to improve theatre and elective exposure for myself and future collaegues.MethodWe designed a traffic light system of safe junior medical staffing over an acute and elective site to highlight to the consultant body that elective learning opportunities were minimal. We then changed the rota to ensure core surgical trainee were able to have more elective theatre and clinic time and the foundation year 1 doctors were able to maximise their learning in the busy acute centreResultsPrior to the changes there were only 2 in 5 (40%) days where there was a green light, i.e allowing safe staffing on both sites and elective learning opportunities. Following the initiation of the new timetable this increased to 63%. We quantified the increase in training opportunities by measuring the amount of work based assessments logged per day before and after the changes. Following the changes there was an increase by a factor of 2.29 per day in the number of cases logged. ConclusionTaking control and initiating change is essential to ensuring we make the most of the time we have in placements. By recognising shortcomings in a rota or timetable and making simple changes we can increase the time spent in theatre and clinics.
Residual stresses in high-strength steel welded square box sections
Authors: Somodi Balázs , Kollár Dénes , Kövesdi Balázs , Néző János , Dunai László
Published: August 2017

Previous research has shown that the residual stresses in high-strength steel (HSS) members can be smaller than those in normal-strength steel structures. To investigate the residual stress distribution in HSS structures, a complex experimental and numerical research programme was carried out on welded square box sections at the Budapest University of Technology and Economics. The test specimens were obtained from three different manufacturers using six different steel grades (S235, S355, S420, S460, S500 and S960). Parallel to the laboratory tests, the effect of the welding process on residual stresses was also studied using a numerical welding simulation technique. The shape and intensity of the residual stress pattern on square box section members were also determined by numerical simulations and compared with the test results. The observed tendencies in the tests and numerical simulations were analysed with respect to the effect of yield strength and section dimensions on the residual stress distribution and magnitude.
Understanding the Role of Physical Leisure Activity in Stress Coping Process for Family Caregivers
Authors:   The Tourism Sciences Society Of Korea, Lee Bo-Mi
Published: August 2017

The purpose of this study is to recommend physical leisure activity as a stress coping strategy for family caregivers who are under chronic stress and to explore its role in the stress coping process. In this study, qualitative research was conducted. This study adopted a phenomenological approach which focused on “what people experience and how they interpret the world.” The interviewees were 8 family caregivers who had been taking caring of their family member. These family members were patients in need of long-term care who received social nursing care services for less than 4 hours a day. The data were collected from May to October 2016, and a semi-structured interview guide structured the interviews. The analysis of the interviews showed that family caregivers who had been involved in physical activity were able to continuously relieve their stress and experienced positive emotions. This implies that physical activity has a positive impact on their ‘problem-focused’ and ‘meaning-focused’ coping strategies for managing their daily stress. Finally, this study provides implications for practical counseling and policy development for family caregivers through a deep understanding of the role of physical activity as a means of chronic stress management for family caregivers.
An Empirical Study of the Relationship between the Emotional Labor-Type and Subsequent Burn Out of Airline Employees
Authors:   The Tourism Sciences Society Of Korea, Koh In-Kon , Moon Myung-Joo
Published: August 2017

In this study, we investigated the effects of the emotional labor of airline company employees upon burnout. After a review of prior studies, we defined the burnout concept and found two sub dimensions of burnout, which are emotional/physical exhaustion and depersonalization. We also developed an exploratory trial of emotional labor type built upon a few key prior studies and examined whether these types moderated the effect of emotional labor. The investigation of the relation between emotional labor components and burnout revealed that surface acting had a statistically significant positive effect on both sub dimensions of burnout. Deep acting however had a statistically significant negative effect on depersonalization and showed very big standardized beta coefficient compared to surface acting, but not on emotional/physical exhaustion. While testing for parallelism, we found a moderating effect of emotional labor type on emotional/physical exhaustion, but in terms of depersonalization, the moderating effect of emotional labor type was found only in surface acting. Interestingly, the averages of emotional/physical exhaustion and depersonalization in the positive emotional labor group were lower than those in the neutral emotional labor group. We also investigated the leisure type of respondents and the demographic variables related to emotional labor components, job satisfaction and burnout in order to suggest several fruitful implications.
A study to assess frequency of peripheral arterial disease in patients presenting with acute coronary syndrome
Authors: Mukherjee Somnath , Kumar Prashant , Sinha D. P.
Published: August 2017

Background: To determine the frequency of peripheral arterial disease (PAD) in patients presenting with acute coronary syndrome (ACS) and association of PAD with different risk factors of coronary artery disease (CAD) and to look for in hospital outcome of ACS patients with or without PAD.Methods: This cross-sectional observation study was undertaken in the department of cardiology, IPGME&R Hospital, Kolkata from June 2015 to August 2016 to recruit 199 consecutive patients admitted with ACS and were evaluated with detailed clinical history, physical examination, ABI (Ankle Brachial Index) measurement, echocardiography and appropriate blood investigations.Results: Among 199 total ACS patients, STEMI was the predominant mode of presentation (71.86%) and majorities were male. PAD was seen in 26 patients and mean age was 56.68±8.84 years. Factors independently related with PAD in acute coronary syndromes are hypertension (OR- 1.49; 95% CI: 0.615-3.232), diabetes (OR- 2.55;95% CI : 0.9762-6.6665), smoking (OR-2.55; 95% CI: 1.055-6.19), past history of CVA (OR-11.15;95% CI: 1.77-70.32), LV systolic dysfunction (OR-1.388; 95% CI:0.607-3.1742). 2 and 13 patients died within 7 days of admission among 26 ACS-PAD group (7.69%) and 173 ACS-non-PAD group (7.5%) respectively and most of them had STEMI.Conclusions: Significant numbers of ACS patients are having PAD and older age, male sex, diabetes, hypertension, smoking and LV systolic dysfunction were found to be independent predictors for PAD in ACS patients. Early in hospital mortality was seem to be dependent on clinical presentation, not on presence or absence of PAD.
To study the carotid intima media thickness in patients of fatty liver disease
Authors: Chouhan Mahendra , Kansal Archana , Trikha Sushma , Gupta Mayank
Published: August 2017

Background: Fatty liver is associated with several atherosclerotic risk factors such as hypertension, diabetes and dyslipidemia. It has also been related to insulin resistance. This association was found in NIDDM patients as well as in non-diabetic subjects. An increased intima-media thickness (IMT) has been shown to be a risk factor for myocardial infarction and stroke. The aim of the present study is to investigate associations between hepatic steatosis and the risk of atherosclerosis.Methods: The present study was carried out on 88 patients of fatty liver disease and 80 controls in the department of General Medicine. An approximate equal number of age and sex matched persons without fatty liver were selected randomly as controls. Both fatty liver disease patients (i.e NAFLD and AFLD) and control group were further divided into two categories, one with risk factor for atherosclerosis and other without risk factors. Risk factors for atherosclerosis were taken according to ATP III guidelines.Results: When comparison of mean CIMT was done in NAFLD, AFLD and controls in a particular age group, significant difference was found in mean CIMT (both sides) in age group 40-49 yrs (p value 0.03, 0.002 for right and left respectively). The difference was also significant in mean CIMT of right in age group 18-24 yrs (p value 0.015) and in >60 years (p value 0.03). Among, NAFLD patients, for left mean CIMT p value was 0.0001, for right mean CIMT p value was 0.0001. Among AFLD patients, for left mean CIMT p value was 0.006 and for right mean CIMT p value was 0.0022. Only statistically significant difference was found in mean CIMT (left) in grade II fatty liver (p value 0.04). NAFLD and controls without risk factors for atherosclerosis, mean CIMT (both side) in NAFLD was found to be significantly more than control (p value 0.04). AFLD patients and controls without risk factors for atherosclerosis, mean CIMT of both side in AFLD patients was found to be significantly more than controls (p value for left CIMT 0.02 and for right CIMT 0.00001).Conclusions: CIMT was found to increase with advancing age in all three group i.e. NAFLD, AFLD and control group. CIMT was more in patients of fatty liver disease (both NAFLD and AFLD) having risk factor for atherosclerosis as compared to those without risk factors. Both NAFLD and AFLD are associated with increased CIMT in comparison to control group. As such all NAFLD and AFLD patients should be investigated for carotid atherosclerosis, as its early detection and management may be helpful in limiting the inherent complications of atherosclerosis.
Ensinar pela pesquisa: Porque não?
Authors: Otobelli Elisete Salvador , Dallacua Graziele , Zanatta Neiva
Published: August 2017

Este trabalho descreve uma investigação realizada com professores de uma escola da rede pública estadual do Rio Grande do Sul que visou identificar se o método científico está ou não sendo utilizado como estratégia didática, qual a concepção dos professores sobre o valor do método científico e a importância do seu papel na construção do conhecimento. A desatenção e/ou a desmotivação de alguns alunos durante as aulas podem levar o professor a refletir sobre as alternativas para motivá-los e comprometê-los com seu aprendizado. Uma possibilidade é trabalhar a pesquisa científica como meio para que o aluno participe ativamente da sequência didática compartilhando dúvidas e descobertas. As Diretrizes Curriculares Nacionais orientam para que o processo ensino-aprendizagem seja ressignificado com a utilização da pesquisa como princípio pedagógico e o conhecimento científico faça parte do cotidiano escolar. A partir de trabalhos teóricos, ressalta-se a necessidade de o professor refletir sobre sua prática e avançar além da cópia e reprodução, adotando um ensino que privilegie a pesquisa, pressuposto para a emancipação intelectual do indivíduo. Assim, realizou-se uma avaliação diagnóstica com professores, onde os resultados apontam que a maioria dos professores não estudou o método científico na sua graduação, logo não o aplicam em sala de aula, apesar de considerá-lo importante para a aprendizagem. Diante destes resultados, os cursos de formação acadêmica, principalmente em licenciatura, precisam preparar satisfatoriamente o profissional para trabalhar com o método científico em sala de aula. Dessa forma o processo de ensino-aprendizagem não se limitará à cópia e reprodução, mas estará sustentado na formulação de perguntas e na procura por respostas. http://dx.doi.org/10.18226/23185279.v5iss1p26
Estudo do caso Klayman v. Zuckerberg and facebook: da liberdade de expressão ao discurso do ódio/Study of the case klayman v. zuckerberg and facebook: from freedom of speech to hate speech
Authors: Leal da Silva Rosane , Bolson Dalla Favera Rafaela
Published: August 2017

Este artigo expõe e analisa o caso Klayman v. Zuckerberg and Facebook para, a partir dele, discutir temas atuais e controversos relacionados à colisão de direitos decorrentes das interações no site de rede social Facebook. Para tanto, foi utilizado o método de abordagem indutivo, tendo em vista que a pesquisa partiu da narrativa desse caso específico para depois tratar de assuntos gerais como a liberdade de expressão, notadamente a religiosa, verificando quando seu exercício excessivo pode configurar discurso do ódio. Já o método de procedimento empregado foi o monográfico, utilizado para selecionar e analisar o primeiro caso de discurso do ódio propagado no site de rede social Facebook, nos Estados Unidos, país que prioriza a liberdade de expressão em face aos demais direitos. Ainda que solução do caso seja adequada ao sistema jurídico estadunidense ela se mostra apartada da moderna teoria sobre os direitos humanos, que não atribui caráter absoluto a um direito quando em colisão com os demais. Ademais, o excesso no exercício da liberdade de expressão religiosa, ao derivar para a propagação do ódio e da violência não parece adequada aos valores do respeito e da dignidade da humana, essenciais para a convivência pacífica na sociedade em rede. AbstractThis paper exposes and analyzes the case Klayman v. Zuckerberg and Facebook for from it, discuss current and controversial issues related to the collision of rights arising from interactions on Facebook social networking site. Therefore, it was used the inductive approach method, given that the research came from the narrative of that particular case and then address general issues such as freedom of speech, notably religious, checking when excessive exercise can configure hate speech. The method of procedure employed was the monographic, used to select and analyze the first case of spread hate speech on Facebook social networking site, in the United States, which gives priority to freedom of speech in relation to other rights. Although if the solution is adequate to the American legal system, it shows apart from the modern theory of human rights, which does not give absolute character to the right when in collision with others. In addition, the excessive freedom of religious expression, to drift into the spread of hatred and violence does not seem adequate to the values of respect and dignity of the human, essential for peaceful coexistence in the network society. KeywordsHuman dignity; Hate speech; Klayman v. Zuckerberg and Facebook; Freedom of speech; Religion.
As investigações em biotecnologia e suas implicações para o direito / Investigations in biotechnology and its legal implications
Authors: Flores Nilton Cesar , Corrêa Alexandra Barbosa de Godoy
Published: August 2017

Resumo: A relação do homem com a natureza sofreu nos últimos anos radicais modificações, principalmente quando se trata da interferência do homem sobre a natureza através da tecnologia. A revolução biotecnológica se por um lado possibilitou ao homem intervir na natureza como uma promessa de um futuro melhor para a humanidade, por outro constitui-se em uma ameaça a própria sobrevivência do homem. Este estudo busca refletir sobre as relações da ética com o direito, e, especificamente, entre bioética e o biodireito, pois até então, nunca o homem teve a sua disposição a evolução e a modificação da sua espécie ou das demais formas de vida. Com o uso da técnica, surgiu para o homem esta possibilidade. Antes disso, a evolução humana e de toda a natureza era realizada por uma mutação produzida naturalmente, onde a ordem do todo era assegurada pela seleção natural.Palavras-chave: Biotecnologia, Ética, Bioética, Biodireito, ResponsabilidadeAbstract: Man's relationship with nature has undergone radical changes in recent years, especially when it comes to the interference of man over nature through technology. If on one hand, the biotechnology revolution made it possible for man to intervene in nature, as a promise of a better future for humanity, on the other constitutes a threat to human survival itself. This study aims to discuss about the relations between ethics and law, specifically between bioethics and biolaw, because until then, man never had at his disposal the evolution and modification of its kind or other forms of life. With the use of technique, this possibility arose for man. Before that, human and all-nature evolution resulted from a natural mutation, in which general order was assured by natural selection.Keywords: Biotechnology, Ethic, Bioethics, Biolaw, Responsability
Conversão da ação individual em ação coletiva: análise do conteúdo do artigo 333 do CPC/2015, das razões do veto da presidente da república e do aproveitamento do instituto no atual sistema processual/ Conversion from individual in collective action: analysis of the content from the article 333 in CPC/2015, the reasons of the veto of the President of the Republic and the use of the institute on current procedural system
Authors: Cambi Eduardo , Fogaça Marcos Vargas
Published: August 2017

O presente trabalho busca difundir o processo coletivo como instrumento para a melhoria da prestação jurisdicional. Também pretende a concretização das garantias constitucionais do direito processual brasileiro, corolários do devido processo legal coletivo, a partir de uma análise da conversão da ação individual em ação coletiva. Tal sugestão estava presente originalmente no artigo 333 do Código de Processo Civil de 2015 (NCPC), cuja inovação foi vetada pela Presidência da República. Para tanto, utiliza-se do método analítico de decomposição do instituto para analisar melhor cada especificidade. A conversão da demanda individual em demanda coletiva, prevista no texto vetado do NCPC, traria grandes conquistas a efetivação da justiça qualitativa, prestada de forma célere e efetiva. Assim, verifica-se a inconsistência do veto, uma vez que o instituto não estava mal disciplinado e permitia a convivência harmônica das técnicas de tutela coletiva de direitos com repercussão individual com as técnicas individuais de repercussão coletiva na sistemática processual civil brasileira. A partir da análise do incidente de coletivização, procura-se verificar em que medida tal instituto ainda pode ser aproveitado no atual sistema processual brasileiro.Palavras chave: Processo coletivo. Conversão da ação individual em ação coletiva. Veto ao Código de Processo Civil de 2015.AbstractThis study aims to spread the collective process as an instrument to the improvement of jurisdictional assistance and implementation of the constitutional principles of the Brazilian procedural law, corollaries of collective due process, on the basis of the analysis of conversion from individual in collective action, presents originally on article 333 of Civil Procedure Code of 2015, which was vetoed by the Presidency of the republic. Therefore, the analytical method of decomposition institute is used to better analyze each specificity. As the institute was regulated, the conversion from individual in collective action would bring great achievements to qualitative justice enforcement. Accordingly, there is inconsistency in Presidency’s veto, considering the institute wasn’t weak disciplined and there was the need for harmonious coexistence of rights collective protection techniques with individual techniques of collective repercussion on Brazilian civil procedure system.KeywordsCollective process. Conversion from individual in collective action. Veto on the Civil Procedure Code of 2015.
MENGURANGI GAP PERGURUAN TINGGI DENGAN DUNIA KERJA: UPAYA PENINGKATAN KUALITAS SUMBERDAYA MANUSIA
Authors: Fitri Agus Zaenul
Published: August 2017

The high capability for managing Higher Education (HE) is necessary which include adopting of modern management principles that focus on quality, continous improvement and customer satisfaction. Globalization era is competation era, so HE must based quality in any of its processed. The students of HE that still studying need a product of motivation and double communication that are; science, academic title, skill, experience, belief and good behaviour on the contex of balance. All of them need to work in workplace expected a better life in this world is systematic attempt to increase human resources quality. There are four points on education field, namely; average and opportunity of education, relevancy with development, quality and efficiency. Therefor HE needs to support a certain aim to increase their level lecturer qualification with next educational level or non-degree course in order to enhance a quality of human resources resulted automatically will support a quality of education at HE.

Keywords:  Gap, Pendidikan, Dunia Kerja, SDM
URGENSI MANAJEMEN PENDIDIKAN DALAM PENGEMBANGAN LEMBAGA PENDIDIKAN ISLAM
Authors: Choir Abu
Published: August 2017

Manajemen pendidikan diakui sebagai salah satu aspek terpenting dalam pendidikan dewasa ini. Hal demikian karena manajemen pendidikan telah menjadi aktivitas penopang mutu pendidikan, bahkan telah menjadi ciri dan indikasi dari mutu pendidikan itu sendiri. Sekalipun manajemen pendidikan, bukan unsur utama pendidikan, tetapi pendidikan bermutu seringkali diukur dari aktivitas manajemen pendidikan ini. Oleh karena itu, manajemen pendidikan yang baik perlu diupayakan sebagai ikhtiyar mengembangkan mutu pendidikan.

Keberadaan konsep dan praktik manajemen pendidikan dewasa ini dirasakan perlu ada sentuhan baru. Hal demikian karena manajemen pendidikan merupakan ilmu terapan manajemen dalam dunia pendidikan. Sebagai ilmu yang berkembang dari dunia bisnis, norma dan etika keilmuan manajemen tidak dapat dipisahkan dari motif-motif ekonomi, hubungan manusiawi, dan aspek-aspek organisasi. Padahal dirasakan ada hal-hal fundamental pendidikan yang tidak bisa sekedar dengan pendekatan bisnis. Bahkan sebagaimana lazim pada keilmuan barat, persoalan moral dan etika seringkali terlepas dari pengembangan ilmu manajemen itu sendiri.
Tulisan ini lebih menekankan pada upaya menemukan alternatif bagi wajah baru manajemen pendidikan dengan memberi sentuhan nilai dan etika islami untuk mengembangkan lembaga pendidikan Islam
KOMPENSASI SEBAGAI ALAT PENINGKATAN KINERJA DALAM BINGKAI AGENCY THEORY
Authors: Sulistiani Dwi
Published: August 2017

Agency theory looked at the relationship between the owner (the principal) and management (agent). Compensation given to overcome problems in the theory of agency, ie the difference between the interests of owners and agents. Compensation system is designed organization aims to motivate employees to improve their performance and retain competent employees. In order to work incentive
compensation, corporate boards must choose a level measurement and precise performance. Performance-based Reward twofold benefit: informing and motivating.
The purpose of this paper is to review how compensation as a performance enhancement tool. The research method uses literature study and its conclusions are: 1. The compensation was given to address the problems in the theory of agency (the difference between the interests of owners and agents). 2. The compensation system is designed organization aims to motivate employees to
improve their performance and retain competent employees. 3. To work incentive compensation, corporate boards must choose a level measurement and precise
performance. The measurement system there are two traditional compensation (use of accounting profit that measure the past) and the stock price (measuring the
future).
KEPEMIMPINAN KEPALA SEKOLAH DALAMMENINGKATKAN MUTU PENDIDIKAN
Authors: Achmad Abdul Kholid
Published: August 2017

As an educational leadership, principals have a duty and responsibility which is quite heavy. Principals through their role and responsibilities to delegate it to aides and other parts. principal leadership in improving the quality of education include: instructive leadership style, leadership style consultative, participative leadership style, delegative leadership style and the quality of education through the process of determining the in-put and out-put processes (graduate).Efforts to improve the quality of school education is needed coaching to teachers and employees by the principal through (1) leadership style instructive addressed to teachers and employees who lacked the academic ability and spirit of performance is less, (2) a consultative leadership style in fostering the ability of teachers and employees of academic less and and the spirit of good works, (3) participative leadership style in fostering teachers and employees who have good academic ability and less fervor employees who have good academic ability, and excellent in performance.
Keywords: Principal, The Quality of Education
STRATEGI PIMPINAN DALAM PENINGKATANBUDAYA KERJA DI PERGURUAN TINGGI
Authors: Rohmah Noer
Published: August 2017

The college is one of the dominant social institutions and the effect on the culture of a nation is also responsible for the transmission of culture from one generation to another as well as preservation. Universities at this time to be ready to face the challenges of globalization and produce graduates who can compete and fill the global era. For that universities must be able to become an institution that global perspective as well as the resources of international standard. Therefore, it is necessary to change the mindset of college becomes mindset following the change, which is oriented on creating a work culture that is more dynamic, productive, and competitive. As for some of the strategies that can be taken by the leadership for the improvement of work culture to make it more dynamic and competitive of them are; (1) creating a smart cultural organization, (2) build employee morale order dynamic competition, (3) improve emotional intelligence in building relationships work, and (4) improve communication in relationships creating work team.

Keywords: strategy, improvement of work culture
URGENSI PELAYANAN PRIMA DALAM PENINGKATAN MUTU PEMBELAJARAN DI LEMBAGA PENDIDIKAN ISLAM
Authors: Yaqien Nurul
Published: August 2017

Every education institution especially Islamic education institution properly provides the best learning services in developing the effort of student quality. Services in education is an absolutely student needs, especially services in developing learning quality, moreover seeing the needs of competitive era. Student’s competence will compete with another competence both in own country and global world particularly in ASEAN region. To undertake the best services in every Islamic education institution, each circle academician of education needs to know the best service concepts. By knowing it that is expected all circle academicians could provide the optimal services for implementing qualified learning. The existence of qualified learning that expected to be able to make excellent generation in all aspects both in religion and general.
Keyword: Excellent Service, Quality Improvement, Learning
PERGESERAN PARADIGMA SISTEM INFORMASI MANAJEMEN
Authors: Pramitha Devi
Published: August 2017

Management Information Systems (MIS) is a field that began to develop since the 1960s. Although there is no single consensus, it is generally defined as a driver's license system that provides information used to support the operation, management, and decisionmaking in organization. Prainformasional in the community, the people in it using a rigid paradigm assisted by intuition, the basis used by them to select the types of information needed is often not obvious because it is colored by the subjective nature of perception. But then in today's modern society, in addition to the paradigm shift that uses a creative
approach to merger, also using the scientific paradigm that enables the selection of information can be done quickly and accurately. In the world of education though, MIS become one of the important factors to improve services at the same time saving for education. With advances in the development of education in Indonesia, both from an
administrative or technological aspect, the process of education services in Indonesia should be done effectively and efficiently. Therefore, to develop the quality of education needed some support facilities, where one of the supporting facilities is the application of information technology in the field of Management Information Systems
Keywords: Management Information System, Paradigm Shift, Education
Pengembangan Manajemen Berbasis Sekolah
Authors: Saefrudin Saefrudin
Published: August 2017

Education is an important part of the national development process that helps determine the economic growth of a country. Education is also an investment in human resource
development, where the improvement of skills and abilities is believed to be a factor supporting human efforts in navigating a life full of uncertainty. The variety of school environment conditions and the varied needs of students in the learning process coupled with Indonesia's highly complex geography, often can not be fully appreciated by the central bureaucracy. Therefore, in the process of improving the quality of education needs to find an alternative model of school management. This led to the birth of the concept of school-based quality improvement management. The purpose of this discussion is to describe the concept of management in accordance with
the needs of schools.

Key Word: Development, School Based Management
Post-Revision Instructions and Pain Relief
Authors: Smillie Christina , Genna Catherine Watson , Murphy James , Hazelbaker Alison K. , Kaplan Martin , Douglas Pamela , Martinelli Roberta , Marchesan Irene , Baeza Carmela
Published: August 2017

What should parents do after their babies’ tongue-ties have been revised? This is one of the most-contentious issues when considering tongue-tie. Our panelists differ in their recommendations, and this article shows the range of views. This article also includes recommendations regarding pain relief.
Scope of Practice for IBCLCs and Identifying via Social Media
Authors: Genna Catherine Watson , Murphy James , Hazelbaker Alison K. , Kaplan Martin , Smillie Christina , Martinelli Roberta , Marchesan Irene , Baeza Carmela , Douglas Pamela
Published: August 2017

As we describe in “When Tongue-Ties Were Missed: Mothers’ Stories,” tongue-tie is often missed and mothers suffer as a result. Furthermore, many health-care providers do not believe that tongue-tie is real. These realities have often left IBCLCs out on the frontiers as possibly the only health-care providers in their communities who recognize tongue-tie. In addition, mothers have found experts, and each other, on social media. What is within the Scope of Practice for IBCLCs in these situations? Our panelists describe some of challenges of practicing in the age of social media and when tongue-tie is disregarded. The Scope-of-Practice issues are also described in “IBCLC Scope of Practice for Tongue-Tie Assessment.”
When Tongue-Ties Were Missed
Authors: Kendall-Tackett Kathleen
Published: August 2017

When we asked for mothers to tell us their stories of tongue-tie, responses flooded in. A theme in many of these stories is health-care providers not listening when mothers said they were in pain. The mothers’ related stories of painful nipples, babies breastfeeding “all the time,” and failure to thrive because of low milk production. Mothers’ voices were not heard because health-care providers minimized their concerns. Most of these mothers persisted with breastfeeding despite the problems. Eventually, the tongue-ties were correctly identified and revised, and the difficulties resolved. Other mothers were not able to continue breastfeeding. A smaller percentage of mothers described revisions that had harmful effects on their babies and that did not fix the breastfeeding problems. (Editor’s Note: We, unfortunately, received too many stories to include in this issue, but we will include all of them in the Clinical Lactation Monograph.)