bluuebunny/crossref_metadata_2025 huggingface dataset:
Reactualization Islamic Theology in Education: Designing Curriculum, Method Learning, and Technology Integration for Transformation Educative
Authors: Asep Abdullah  , Qiqi Yuliati Zaqiah  , Mohammad Ridwan  , Sally Badriya Hisniati  , Mahmud  , Mohammad Erihardiana
Published: April 2024

The development of Islamic education has become the main focus of the effort to formulate return religious teachings to be more in accordance with the demands of the times and achieve transformation in system education. This article aims To explore How Islamic theology is actualized in the aspect of education, considering design curriculum, methods of learning, and integration technology. The method research used is qualitative analysis with studies of comprehensive library. Through a review of in-depth literature and articles, this identifies draft reactualization of Islamic theology in context education and explains the goals and approaches required to achieve it. Research results highlight the importance of the integration of values of Islamic theology in curriculum-relevant education with the demands of the times. Besides that, This review is about using interactive methods of learning, like discussion groups and technology, to facilitate a deep understanding of Islamic teachings. With the integration of Islamic theology in the curriculum, implementing method learning interactive, and utilising technology in a way that is wise and transformational, more educational , extensive and sustainable can achieved in Islamic education.
Analysis of Renewable Energy Potential in South Sulawesi, Indonesia
Authors: Dwiputra Felix , Saputri Fahmy Rinanda
Published: April 2024

The COVID-19 pandemic led to a temporary reduction in global energy usage, offering a glimpse of environmental benefits. However, subsequent rebounding energy demands underscored the need for cleaner alternatives. This paper examines renewable energy options for Indonesia, focusing on South Sulawesi. The region boasts significant solar irradiation and hydropower potential, with biomass also offering viable energy generation. While wind power is less potent, certain areas with high wind speeds could benefit. Transitioning to renewable sources could mitigate environmental and health concerns, addressing pollution and temperature rise. By leveraging these abundant resources, South Sulawesi could secure sustainable energy while minimizing adverse impacts on both the environment and public health.
Mapping the Research Landscape: A Bibliometric Analysis of Islam's Role in Sustainable Development
Authors: Saky Sheikh Abu Toha Md , Azani Mohammad Zakki , Shohib Muhammad Wildan , Islam Md Nurul
Published: April 2024

This bibliometric analysis delves into the expansive landscape of research where Islam intersects with sustainable development, covering the period from 1991 to 2023. The dataset, comprising 586 documents from 354 sources, signifies a dynamic and rapidly growing field, with an impressive annual growth rate of 11.44%. The relatively low average document age of 5.08 years highlights the contemporary nature of the research, while the high average citations per document (5.795) and substantial reference count (25,019) underscore the field's influence and interconnected character. Key contributors include Malaysia, with 369 articles, and Indonesia with 269 articles, emphasizing their leadership roles. The USA emerges as the most cited country, with 284 total citations, reflecting its significant impact. The global collaboration map highlights Malaysia as a central hub, collaborating notably with Indonesia, Bangladesh, and the USA, illustrating the collaborative nature of research in this area. Trending topics reveal a shift towards holistic themes like environmental protection, ethics, and public health. The enduring presence of keywords such as "sustainable development" and "Islam" underscores central themes, providing valuable insights into the evolving discourse. These discoveries have important ramifications for scientific education, strengthening tactics and curriculum via a deeper comprehension of sustainable development in Islamic contexts. This research fosters a more comprehensive approach to sustainability education by addressing global concerns with cultural and religious components and bridging multidisciplinary barriers by clearly highlighting these links. This increases the study's applicability to a wide variety of multidisciplinary audiences, such as academics, educators, and decision-makers who want to improve scientific education within Islamic contexts.
Research and Development of Mathematics Teaching Material Integrated with Islamic Values: A Systematic Literature Review
Authors: Rahmah Hania , Turmudi Turmudi , Ghifari Muhammad Tareq
Published: April 2024

Mathematics teaching material integrated with Islamic values can support the achievement of mathematics learning objectives in cognitive and affective aspects. This research aims to conduct a literature review related to the research and development of mathematics teaching material integrated with Islamic values. The method used in this research is a Systematic Literature Review (SLR) which consists of 36 studies in the period 2018 - 2022. The key question in this research is how the articles regarding research and development of mathematics teaching materials integrated with Islamic values are distributed based on year of publication, level of education, Islamic values, and mathematics topics. The results of this research show that most studies related to mathematics teaching materials integrated with Islamic values were carried out in 2020, researchers conducted a lot of research on teaching materials integrated with Islamic values at the junior high school level, teaching materials integrated with Islamic values were mostly applied to the topic of numbers, and the most widely used Islamic value is the Quran. This research is expected to be a reference to carry out further research related to mathematics teaching materials integrated with Islamic values, and using mathematics teaching material integrated with Islamic values can be the option to make the mathematics learning process more meaningful.
Effect of Starvation on Branched-Chain a-Keto Acid Dehydrogenase Activity in Rat Heart and Skeletal Muscle
Authors: Holeček M
Published: April 2024

The aim of the present study was to investigate changes in the activity of branched-chain a-keto acid dehydrogenase (BCKAD) in skeletal muscle and the heart during brief and prolonged starvation. Fed control rats and rats starved for 2, 4 and 6 days were anesthetized with pentobarbital sodium before heart and hindlimb muscles were frozen in situ by liquid nitrogen. Basal (an estimate of in vivo activity) and total (an estimate of enzyme amount) BCKAD activities were determined by measuring the release of 14CO2 from a-keto[1-14C]isocaproate. The activity state of BCKAD complex was calculated as basal activity in percentages of total activity. Both basal and total activities and the activity state of the BCKAD were lower in skeletal muscles than in the heart. In both tissues, starvation for 2 or 4 days caused a decrease in the basal activity and activity state of BCKAD. On the contrary, in the heart and muscles of animals starved for 6 days a marked increase in basal activity and activity state of BCKAD was observed. The total BCKAD activity was increasing gradually during starvation both in muscles and the heart. The increase was significant in muscles on the 4th and 6th day of starvation. The demonstrated changes in BCKAD activity indicate significant alterations in branched-chain amino acid (BCAA) and protein metabolism during starvation. The decreased BCKAD activity in skeletal muscle and heart observed on the 2nd and 4th day of starvation prevents the loss of essential BCAA and is an important factor involved in protein sparing. The increased activity of BCKAD on the 6th day of starvation indicates activated oxidation of BCAA and accelerated protein breakdown.
Vergi Uyuşmazlıkları İçin Anayasa Mahkemesine Yapılacak Bireysel Başvurularda Potansiyel Sorunlar
Authors: Özyalçın Özgenur
Published: April 2024

Türk hukukunda 23 Eylül 2012 tarihinden sonra kesinleşen nihai işlem ve kararlar aleyhine Anayasa Mahkemesi’ne başvuru imkanı olarak biçimlendirilen bireysel başvuru yolu, uygulanmaya başlandığı tarihten bu yana ülke içi hak arama mekanizmalarının geliştirilmesinde önemli bir adım olarak nitelendirilmiştir. Bireysel başvuru T.C. Anayasası ile güvence altına alınmış bir hak olmasının yanı sıra mahkemeye erişim hakkının ülke içindeki nihai noktasını oluşturduğundan etkinliği, erişilebilirliği ve açık kural setleriyle düzenlenmiş olması büyük önem arz etmektedir. Bu çerçevede; bireysel başvuru hakkına ilişkin hükümleri havi yasal düzenlemelerin kendi içinde yeknesak olması temel gerekliliktir. Olası belirsizliklerin T.C. Anayasa Mahkemesi tarafından göz önüne alınması gelecek içtihatlar bakımından bir yumuşak yorum yaklaşımı sağlayarak hak kaybı yaşanmasını engelleyebilir. Mahkeme tarafından bu yönde bir farkındalık geliştirilse dahi bunun ancak yasama sürecinin hantallığına karşı geçici bir güvence oluşturacağına şüphe yoktur. Bir hukuk devletinden beklenen, sorun ve eksikler uygulamada ne kadar tolere ediliyor olursa olsun yasal düzenlemelerin uygulamada bir toleransa ihtiyaç duyulmayacak biçimde netleştirilmesi olacaktır.
Türk hukukunda vergi düzenlemeleri tek bir Kanun altında toplanmamış olup mevzuat içinde dağınık durumdadır. Bu dağınıklık tüm düzenlemelerin aynı anda göz önüne alınmasını zorlaştırdığı için mevzuat içi boşluk ve çelişkilerin oluşması kaçınılmaz bir netice olarak ortaya çıkmakta, bu aksaklıkların fark edilmesi hak kaybı yaşanmaması bakımından önem arz etmektedir.
Uluslararası Hukuk Sujelerine Uygulanan Yaptırımların Sınırları ve Etkileri
Authors: Arsava Ayşe Füsun
Published: April 2024

Yaptırımlar modern diplomasinin ayrılmaz bir parçası olarak görülmekle beraber Uluslararası Hukuk’ta yeterince ele alınmış bir konu değildir. Yaptırımlar hukuki dayanak ve sınırları itibarı ile oldukça heterojen karakterlidir. Uluslararası politikanın ayrılmaz bir parçası olan yaptırımlar uluslararası politikanın yürütülmesinde öngörülen amaca erişmeyi temin eden bir araç olarak değerlendirilse de etkinliği bakımından tartışılmaktadır. Bugün çok sayıda devletin ve uluslararası örgütün değişik nedenlerle yaptırım uyguladığı görülmektedir. Uluslararası Hukukta yaptırım olarak alınan önlemler çeşitlilik göstermektedir. Bu çerçevede anlaşma hükümlerine istinat eden yaptırımlar ve uluslararası teamül hukukuna istinat eden yaptırımlar arasında ayrım yapılmaktadır. Yaptırımların Uluslararası Hukuk ihlâllerine reaksiyon olarak ilân edilmesi nedeni ile bu bağlamda uluslararası sorumluluk kuralları esas alınmaktadır. Uluslararası ilişkilerde ancak Uluslararası Hukuk ihlâllerinden etkilenmeyen devletler ve uluslararası örgütler de sık şekilde yaptırım ilân etmektedir. Yaptırımların etkinliği yaptırım uygulanan devletin tutumunda değişikliğe yol açıp açmadığına göre değerlendirilmektedir. Yaptırımların etkisi somut ekonomik, siyasi, konjonktürel koşullara bağlıdır. Bu çerçevede yaptırımların, yaptırım muhatabı olmayan bireyler üzerinde doğurduğu etkinin ve bumerang etkinin de gözardı edilmemesi gerekmektedir. Makalede uluslararası ilişkilerde yaptırım kavramı, yaptırımın Uluslararası Hukuk’taki dayanağı, sınırları, Uluslararası Hukuk süjelerine ve kişilere yönelik yaptırımlar arasındaki farklar, (targeted sanctions) yaptırım mağdurları ve yaptırımların etkisi ele alınmaktadır.
1850 Tarihli Ticaret Kanunu’nda ve Osmanlı Hukuk Literatüründe Anonim Şirketler Ve Bu Şirketlerin Tüzel Kişiliği Meselesi
Authors: Korkmaz Müberra
Published: April 2024

Kâr amacı güden bir özel hukuk tüzel kişisi olarak anonim şirket türü, sınırlı sorumluluk ilkesi kapsamında girişimciliğe ve dolayısıyla sermaye birikimine önemli katkı sağlamaktadır. Temel yapı taşını sermayenin oluşturduğu kapitalist sistemin, var olan şirket türlerini zamanla kendi amaçları doğrultusunda şekillendirmesi neticesinde anonim şirketler, bu sisteme en iyi hizmet eden araçlardan biri olarak ortaya çıkmıştır. Söz konusu durumun hukuk düzenine yansımasını gözler önüne seren en önemli hususlardan biri, 19.yüzyılda, gerçek kişilerin değil, onların sermayelerinin toplamından oluşan bu şirketin, bir hukuki şahsiyet olarak tanınmasıdır. Batı kaynaklı bu dönüşüm, Osmanlı Devleti’nde ise Batı’dakinden çok farklı dinamiklerin zorlamasıyla, özellikle yabancı devletlerin etki ve baskılarıyla meydana gelmiştir. Bu dönemde Osmanlı’nın birçok Avrupalı devlet ile imzalamak zorunda kaldığı ticaret antlaşmaları neticesinde meydana gelen “serbest ticaret” düzeni, Osmanlı’nın geleneksel ekonomik ve hukuki yapısında köklü değişimlere sebep olarak liberalleşme ve modernleşme için uygun zemini hazırlamıştır. Bu süreçte, giderek emperyalizmin etkisine daha fazla giren Osmanlı Devleti’nde, modern şirketler hukukunun kabulüyle birlikte bu şirketlerin etkinlik sağlayabilmeleri hükümler öngörülmüştür. Aynı zamanda bu şirket türü, milli amaçlarla yabancı sermaye ile rekabet edebilecek konuma gelmek için Osmanlı devlet adamları ve aydınlar tarafından önemi ortaya konulan ve teşvik edilen bir mekanizmayı da teşkil etmiştir. Ancak neticede umulan fayda, yabancı sermayenin izin verdiği oranda gerçekleşmiş; yabancı sermayeye yardım olmaktan öteye gidememiştir. Osmanlı Devleti’ndeki dini ve geleneksel şartlarla uyumsuzluğuna karşın, anonim şirket türü ve bu şirketlerin tüzel kişi olarak kabulü, söz konusu durumu gözler önüne sermekle birlikte, ekonomik faktörlerin hukuku şekillendirmesine hukuk tarihimiz açısından önemli bir örnek niteliği de teşkil etmektedir.
Kat Maliklerinin Ortak Gidere Katılma Payının Değiştirilmesi
Authors: Şahin Musa Furkan
Published: April 2024

Bağımsız bölüm maliklerinin ortak gidere katılma yükümlülüğü Kat Mülkiyeti Kanunu madde 20’de düzenlenmektedir. Bu maddede bazı ortak giderler bakımından eşit dağılım, bazıları bakımından ise arsa payı oranında katılma esası yer almaktadır. Ancak kat malikleri anlaşarak ortak gidere katılma payında değişiklik yapabilirler. Bu anlaşma, kat malikleri kurulu kararı ile veya yönetim planında bu konuda bir hüküm varsa bunun değiştirilmesi ile sağlanabilir. Kat malikleri ortak giderlerin tamamı veya bazıları bakımından farklı bir katılma payını esas alabilirler. Bunun yanında, kat maliklerinin bağımsız bölüm maliklerinden bazıları için katılma payını değiştirmeleri veya kaldırmaları mümkündür. Hâkim, kat maliklerinin ortak gidere katılma payında değişiklik yapmalarına kural olarak müdahale edemez. Ancak bu kararın hakkın kötüye kullanılması niteliğinde olması veya karar için gerekli çoğunluğun sağlanamaması hâllerinde hâkimin müdahalesi mümkündür. Bu makalede, kat maliklerinin ortak gidere katılma payının değiştirilmesi, katılma payının belirlenmesinde esas alınabilecek unsurlar, katılma payının değiştirilmesi usulü ve hâkimin müdahalesi incelenmektedir. Bu hususlar, İsviçre Medeni Kanunu’nun 712h maddesi ile karşılaştırmalı olarak ele alınmaktadır.
Konut Kira Bedeli Artışında Belirlenen Yasal Üst Sınırın Anayasal Hak ve İlkeler Bakımından Değerlendirilmesi
Authors: Demir Hande Seher
Published: April 2024

08.06.2022 tarih 7409 sayılı Kanun ve 14.07.2023 tarih 7456 sayılı Kanun, yenilenen kira sözleşmelerinin kira bedeli artışlarında uygulanmak üzere yüzde 25 oranında yasal üst sınır belirlemiştir. Anılan yasalar, sözleşme özgürlüğü, konut hakkı, mülkiyet hakkı, hukuk devleti, sosyal devlet gibi hak ve ilkelerle temas halindedir. Alegorik bir anlatımla devlet bir terazi kurmuş, terazinin bir kefesine kiraya verenin mülkiyet hakkını diğer kefesine kiracının barınma hakkını koymuştur. Esasen sözleşme özgürlüğü ve özel hukukun tabiatı gereği terazi, akdedilen kira sözleşmesi taraflarının serbestçe belirlediği bir denge içindedir. Fakat devlet, tarihten bugüne anılan dengeye müdahale etmekte zira terazinin -kamu düzenini bozacak ölçüde- kiracı aleyhine dengesiz olduğunu düşünmektedir. Makalede, terazi metaforundaki müdahalenin hukukiliği, Yargıtay, AYM ve AİHM’in içtihatları ışığında tartışılmıştır. AİHM, AİHS P1-1 için geliştirdiği bir analiz yöntemi olan Üç Kural Analizi bağlamı içinde, mülkiyetin kamu yararına kullanımının kontrolünü amaçlayan müdahalelere Üçüncü Kuralı uygulamaktadır. Bu denetim pratiğinden hareketle, konuyla ilgili olası bir başvuruda, AİHM’in müdahaleyi -kural olarak- hukukî bulacağı anlaşılmaktadır. AYM ise daha etkili bir ölçülülük denetimi icra eder. Türk yüksek mahkemelerinin emsal kararları ışığında, olası bir başvuruda AYM’in ölçülülük incelemesinden hareketle ihlal/iptal kararı vereceği sonucuna ulaşılmaktadır.
How the Fourth Statistical Account of East Lothian Recorded Developments in the Church in the County Between 1945 and 2000
Authors: Dutton David
Published: April 2024

This article will use the Fourth Statistical Account of East Lothian, which was produced by a consortium of local history societies, to provide a case study of how the church in the county developed between 1945 and 2000. Because East Lothian is the only Scottish county to have a fourth statistical account, the study provides a unique opportunity to trace the development of the church within a Scottish local authority during the second half of the twentieth century. The article will use, as its main sources, essays on four established denominations and the sections on ‘Belief’ in each of the parish entries. It will detail how the Church of Scotland, the Scottish Episcopal Church and the Methodist Church contracted between 1945 and 2000; show that, while the Roman Catholic Church was more stable, it began to suffer from a lack of vocations and the disinterest of younger members of the Catholic population, and that, while the Baptist Church increased its presence in the county and Pentecostal congregations and ‘house churches’ were formed, the Brethren and Church of Christ both declined and, as a consequence, these other churches remained on the margins of the church in East Lothian.
Nighttime Lights Or Happiness: Which One Would A Society Choose?
Authors: Bi Hui Lim  , Tuck Cheong Tang
Published: April 2024

This study discovers evidence of a bidirectional causation between nighttime lights and happiness using the panel Granger non-causality tests of a short (balanced) panel data of 132 countries, within the period from 2008 to 2012. There are different findings throughout the six geographical regions. A bidirectional causation is observed for Latin America and the Caribbean, while a unidirectional causality is from happiness to nighttime lights for East Asia and Pacific, Europe and Central Asia, and the Middle East and North Africa. In Sub-Saharan Africa is found, the situation is from nighttime lights to happiness. These findings are complemented by the impulse response function, various decomposition analysis, and their estimates of panel random (or fixed) effect models. This study offers an insight that nighttime lights are required for a happy society.
MEDIATING EFFECTS OF ISLAMIC BUSINESS SUCCESS ON PRODUCTIVE ZAKAT AND MUSTAHIQ WELFARE
Authors: Ivan Rahmat Santoso  , Syahrir Mallongi  , Siradjuddin  , Muhammad Basir Paly
Published: April 2024

This research aims to determine the effect of productive zakat programs, entrepreneurial motivation, and competence on the welfare of mustahiq through having successful Islamic businesses as interveners. The research applied quantitative analysis method by distributing questionnaires to collect primary data from 111 mustahiq recipients of assistance from zakat institutions. This research employed a path analysis technique with the help of the SEM-PLS (Partial Least Squares) 4.0 program and was used to analyze the influence among variables. The empirical findings indicate that the productive zakat program significantly and positively affects mustahiq's welfare but not the business’s success. Meanwhile, entrepreneurial motivation and competence also significantly and positively affect business success and mustahiq welfare. Interestingly, the success factor for Islamic businesses can mediate the relationship between productive zakat, motivation, and competency on the welfare of mustahiq. This research contributes to the zakat literature by examining the connection between productive zakat, entrepreneurial drive, competency, and the factors influencing the performance of Islamic enterprises in achieving welfare according to Islamic objectives. Practically, the implications of this research are useful for the government as a policymaker in increasing the contribution of zakat institutions to material and spiritual poverty alleviation.
THE IMPACT OF ANCHOR CHARACTERISTICS ON CUSTOMERS' SUSTAINABLE FOLLOW IN E-COMMERCE LIVE BROADCAST—BASED ON THE SURVEY OF TIKTOK USERS IN CHINA
Authors: Li Qi  , Shao Xiaoli
Published: April 2024

With the development of Internet commerce, live broadcast has become a new e-commerce milestone. This study uses SOR model for reference, taking customer perceived value and customer flow experience as intermediary variables, to explore the impact of anchor characteristics on the sustainable follow of customers in the live broadcast room. The research findings demonstrate that the credibility, professionalism, interactivity, and attractiveness of e-commerce anchors have a significant positive impact on customer perceived value and customer flow experience. Customer perceived value and customer flow experience positively influence the sustainable retention of customers in live broadcast rooms. Moreover, these factors act as mediators between the characteristics of e-commerce anchors and the sustainable retention of customers. Therefore, it is imperative for live broadcast e-commerce merchants to adapt their strategies based on anchor attributes in order to enhance customer perceived value and improve customer flow experience. This will effectively guide customers towards sustained engagement and yield favorable marketing outcomes. It is helpful for e-commerce anchors to effectively reduce customer loss and form customer loyalty, and also provides a reference for enterprises to use live broadcast e-commerce for product sales and brand promotion.
Analisis Yuridis Terhadap Perkara Perceraian Nikah Siri
Authors: Nur wahyu illahi
Published: April 2024

The subject raised in this thesis is the existence of a secret marriage but filing for divorce in the Religious Court. The judge uses Article 7 paragraph (3) letter a of the Islamic Law Compilation as a consideration to prove the marriage. This research analyzes the case number 7073/Pdt.G/2021/PA.Kab.Mlg regarding the consolidation of proving marriage and divorce according to positive law in Indonesia. The research method used is empirical research method through interviews and observations at the District Court of Malang with descriptive, evaluative, and prescriptive data analysis. The researcher analyzes the verdict number 7073/Pdt.Kab.G/2021/PA.Mlg using the Legal Ethical Theory, which indicates that the use of Article 7 (3) letter (a) of the Islamic Law Compilation is questionable in terms of legal interpretation when compared to applicable laws and regulations. However, despite this, the case remains valid, but legal certainty in case administration cannot be achieved.
Explicating Botanical Bactericides as an Intervention Tool towards Citrus Canker
Authors: Aslam Naveed , Atiq Muhammad , Rajput Nasir Ahmed , Akram Azeem , Arif Asif Mahmood , Kachelo Ghalib Ayaz , Nawaz Ahmad , Jahangir Muhammad Muzammal , Jabbar Abdul , Ijaz Aniqa
Published: April 2024

Recent research efforts were made to investigate botanical bactericides as an intervention tool for citrus canker. Five botanical extracts (Eruca vesicaria, Eucalyptus globulus, Trigonella foenum-graecum, Nigella sativa, and Citrullus colocynthis) were evaluated at three different concentrations (0.25%, 0.5%, and 0.75%) against Xanthomonas citri pv. citri under in vitro conditions. Among all treatments, two effective plant extracts, alone and in combinations, were assessed at three different time points (7 days, 14 days, 21 days) under greenhouse conditions. In vitro and greenhouse experiments were conducted under a Completely Randomized Design. Results showed that C. colocynthis expressed the maximum inhibition zone (3.22 mm), followed by N. sativa (2.82 mm), T. foenum-graecum (2.68 mm), E. globulus (1.64 mm), and E. vesicaria (1.31 mm) compared to the control. Effective extracts of C. colocynthis and N. sativa were assessed under greenhouse conditions, both alone and in combination, against citrus canker. The minimum disease incidence (18.74%) was exhibited by the combination of C. colocynthis and N. sativa, followed by C. colocynthis (22.59%) and N. sativa (23.27%) compared to the control. Based on these findings, it is recommended that the application of botanical extracts is a reliable strategy for managing citrus canker.
Study on the Population Density of Insect Pests of Broccoli, Brassica Oleracea, in the Jadiriyah Area of Baghdad, Iraq
Authors: Fliah Sawsan Kareem , Mukheif Nabaa Abdul Redha , Kathiar Soolaf Abud
Published: April 2024

A field study was conducted in the fields of the College of Agricultural Engineering Sciences at the University of Baghdad in Al-Jadriya during the 2018 agricultural season. The objective was to survey the population densities of pests affecting broccoli (Brassica oleracea). The results revealed that the broccoli plants in the open field were affected by various pests. On September 24, the highest density of two-spotted red mite (Tetranychus urticae) eggs reached 35 eggs per leaf. On November 12, the highest density of mite nymphs was recorded at 28 nymphs per leaf. The leaf miner, Liriomyza sativae, exhibited the highest density of 23 tunnels per leaf on September 17. Additionally, the highest density of whitefly nymphs (Bemisia tabaci) was observed on October 1 and November 17, reaching 29 nymphs per leaf. The results also indicated the presence of the aphid lion, Chrysoperla carnea, as a natural enemy. Furthermore, the parasitoid Diglyphus isaea was found on the leaf miner, while the parasitoid Eretmocerus mundus was identified on the whitefly. Therefore, understanding the species of pests and their density attacking agricultural crops is crucial. This knowledge allows for the release of natural enemies in the field to mitigate pest infestations.
Impacts of Climate Change on the Number of Days per Generation of the Egg-Parasitoid Telenomus Remus Nixon, 1937 (Hymenoptera: Scelionidae) in Egypt
Authors: El Kenawy Ahmed Hamed , Hassan Hassan Ahmed , Hamza Mohamed Kamel Abdel-samed , El-Sheikh Wael El-zaher Abd El-Hafeez
Published: April 2024

In this research, we forecasted both the degree-day units and annual generations of the egg parasitoid Telenomus remus Nixon, which parasitizes fall armyworm (Spodoptera frugiperda). The aim was to comprehend its potential spread across diverse agro-climatic zones, considering both current conditions and potential future climates. This was achieved by examining the correlation between degree-day units and population fluctuations. Climate change data from the HadCM3 model was utilized, focusing on A1 scenarios recommended by the Intergovernmental Panel on Climate Change (IPCC). We aimed to evaluate how temperature projections are anticipated to impact the annual generations in three Egyptian governorates. The investigation revealed that T. remus populations in Aswan, an Upper Egyptian governorate, exhibited a higher number of generations compared to other regions, namely El Sharkia and Beni Suef governorates, in the current climate. The completion of generations by T. remus in El Sharkia, Beni Suef, and Aswan took 13.42, 12.6, and 10.08 days, respectively. The results highlighted that the average generation period in 2021 was the longest, reaching 13.42 ± 6.17 days in El Sharkia governorate. Predictions suggest that T. remus is anticipated to undergo 23 generations between 2040 and 2060, indicating a two-generation increase from 2021. Conversely, in the Beni Suef governorate, where T. remus completed generations in 10.86 ± 5.72 days, the generation period was the longest in 2021. Projections indicate that T. remus is expected to have 24 generations in 2040 and 28 generations in 2060, compared to 22 generations in 2021. Additionally, Aswan’s T. remus is forecasted to experience 32 generations in 2040 and 35 generations in 2060, up from 29 generations in the 2021 climate. The duration of the first generation took 13, 11, and 12 days in the years 2021, 2040, and 2060, respectively. A comprehensive understanding of thermal requirements and biological factors is crucial for accurately predicting generation duration, serving as a valuable reference for the mass production and preservation of parasitoids.
Feeding Toxicity of Insecticides against Red Palm Weevil, Rhynchophorus Ferrugineus, (Coleoptera: Dryophthoridae) in a Controlled Environment
Authors: Ikhlaq Muhammad , Jaleel Waqar , Noreen Ammara , Amjad Muhammad Ammar , Shehzad Muhammad Basit , Azad Rashid , Akram Bilal , Ayoub Khan Muhammad Faraz , Altaf Lubna , Shabir Kashif , Bashir Muhammad Azhar
Published: April 2024

Rhynchophorus ferrugineus (Olivier, 1790), often known as the Asian palm weevil or red palm weevil (RPW) (Coleoptera: Curculionidae), had long been considered disruptive to many palm trees (Arecaceae), especially date palms. Observing adults of RPW inside the trunk of palm trees was challenging. Date palm trees provided shelter from bad weather for the larvae that lived and fed within. Finding the red palm weevils required dissecting the palm. Damage could occur to almost every commercially planted date palm variety in the nation, including Aseel, Hillawi, Karbalain, Mozawati, Kechen, and Dhaki. All year round, adult red palm weevils could be found inside palm trees, although they were most active in the summer. The primary method of managing RPW was the frequent use of synthetic pesticides, which were used both preventatively and therapeutically in an effort to lessen RPW damage and spread. In the present study, the soft stem dip method was used to evaluate the toxicity of three different insecticides (clothianidin, trichlorphon (systemic), and fipronil). The results showed that LC50 values with 95% CI (µg/ml) after 72 hours were recorded as 4.096 µg/ml in the case of clothianidin + trichlorfon, representing the highest toxicity. Trichlorphon against 3rd instar larvae of the red palm weevil was more toxic compared to clothianidin and fipronil. The study, therefore, suggested that these insecticides need to be properly included in IPM plans to combat this pest. To test and enhance the efficacy of such pesticides in field settings, more work was necessary.
Identification of Cell Wall Invertase Activities in Selected Wheat Cultivars from Sindh for Crop Improvement
Authors: Memon Adnan Rasheed , Bux Hadi , Samoo Muhammad Siddique
Published: April 2024

CWI markers, also known as Cell Wall Invertase markers, play a pivotal role in wheat breeding and crop improvement. These markers help identify wheat varieties with desirable traits related to yield potential, stress tolerance, drought tolerance, and overall crop performance. The CWI gene, found in bread wheat, has been identified on chromosomes 4A, 5B, and 5D, all of which contain the conserved WECPDF domain. The main role of the Cell wall invertase (CWI) gene is to hydrolyze sucrose into glucose and fructose. Harnessing the power of CWI markers contributes to the advancement of sustainable agriculture practices and the development of high-performing wheat varieties to meet the demands of diverse agricultural landscapes. In this study, we investigated the prevalence of CWI markers, specifically CWi21 and CWi22, in wheat varieties cultivated in Sindh, Pakistan. We collected a set of thirteen wheat genotypes cultivated in the Sindh province for the screening of Cell Wall Invertase markers through polymerase chain reactions. Our analysis revealed the diversity of the markers CWi21 and CWi22 in wheat genotypes. The marker CWi21 was present in 30% of the wheat varieties, while CWi22 was detected in 70% of the wheat varieties.
Källarhålet: Utrymme för kreativitet
Authors: Davidsson Birk , Dahllöf Felix , Petersson Pella-Maria , Brignoli David
Published: April 2024

En blogg skapad av fyra SLM-studenter för projektarbetet i kursen 'Att publicera i det medierande offentligheten.'
Bloggen är ämnad att ses som ett magasin dit studenter kan skicka in egenskrivna texter som sedan blir publicerade av redaktionen. Genom att ge en plattform för skribenter som inte har någon annanstans att publicera eller utan någon att läsa deras texter hoppas vi att kunna froda en kreativ gemenskap.
Illuminating microflora: shedding light on the potential of blue light to modulate the cutaneous microbiome
Authors: Serrage Hannah J. , O’ Neill Catherine A. , Uzunbajakava Natallia E.
Published: April 2024

Cutaneous diseases (such as atopic dermatitis, acne, psoriasis, alopecia and chronic wounds) rank as the fourth most prevalent human disease, affecting nearly one-third of the world’s population. Skin diseases contribute to significant non-fatal disability globally, impacting individuals, partners, and society at large. Recent evidence suggests that specific microbes colonising our skin and its appendages are often overrepresented in disease. Therefore, manipulating interactions of the microbiome in a non-invasive and safe way presents an attractive approach for management of skin and hair follicle conditions. Due to its proven anti-microbial and anti-inflammatory effects, blue light (380 – 495nm) has received considerable attention as a possible ‘magic bullet’ for management of skin dysbiosis. As humans, we have evolved under the influence of sun exposure, which comprise a significant portion of blue light. A growing body of evidence indicates that our resident skin microbiome possesses the ability to detect and respond to blue light through expression of chromophores. This can modulate physiological responses, ranging from cytotoxicity to proliferation. In this review we first present evidence of the diverse blue light-sensitive chromophores expressed by members of the skin microbiome. Subsequently, we discuss how blue light may impact the dialog between the host and its skin microbiome in prevalent skin and hair follicle conditions. Finally, we examine the constraints of this non-invasive treatment strategy and outline prospective avenues for further research. Collectively, these findings present a comprehensive body of evidence regarding the potential utility of blue light as a restorative tool for managing prevalent skin conditions. Furthermore, they underscore the critical unmet need for a whole systems approach to comprehend the ramifications of blue light on both host and microbial behaviour.
Time course of cardiac rupture after acute myocardial infarction and comparison of clinical features of different rupture types
Authors: Liang Chendi , Wang Xiaoxia , Yang Peng , Zhao Ru , Li Li , Wang Zhixin , Guo Yanqing
Published: April 2024

Objective

This study aimed to investigate the time course of cardiac rupture (CR) after acute myocardial infarction (AMI) and the differences among different rupture types.

Method

We retrospectively analyzed 145 patients with CR after AMI at Shanxi Cardiovascular Hospital from June 2016 to September 2022. Firstly, according to the time from onset of chest pain to CR, the patients were divided into early CR (≤24 h) (n = 61 patients) and late CR (>24 h) (n = 75 patients) to explore the difference between early CR and late CR. Secondly, according to the type of CR, the patients were divided into free wall rupture (FWR) (n = 55) and ventricular septal rupture (VSR) (n = 90) to explore the difference between FWR and VSR.

Results

Multivariate logistic regression analysis showed that high white blood cell count (OR = 1.134, 95% CI: 1.019–1.260, P = 0.021), low creatinine (OR = 0.991, 95% CI: 0.982–0.999, P = 0.026) were independently associated with early CR. In addition, rapid heart rate (OR = 1.035, 95% CI: 1.009–1.061, P = 0.009), low systolic blood pressure (OR = 0.981, 95% CI: 0.962–1.000, P = 0.048), and anterior myocardial infarction (OR = 5.989, 95% CI: 1.978–18.136, P = 0.002) were independently associated with VSR.

Conclusion

In patients with CR, high white blood cell count and low creatinine were independently associated with early CR, rapid heart rate, low systolic blood pressure, and anterior myocardial infarction were independently associated with VSR.
Media education in Waldorf/Steiner schools
Authors: Neumann Robert
Published: April 2024

This article explores the distinctive approach to media education in Steiner/Waldorf Schools, focusing on delayed introduction of electronic media. Addressing a research gap, the article highlights the unique developmental phases guiding media pedagogy, combining direct and indirect media education and the so called “media maturity tower.” A central focus is the alignment of media pedagogy with the cognitive developmental stages of students. There are three distinct phases addressed in connection with different topics within the school curriculum. These phases underscore the educational commitment to age-appropriate media engagement and enable a comparison between the rather critical stance taken by Steiner/Waldorf Schools and the current trends regarding the use of media in education. The article highlights the need for further research on the long-term impact of the developmental approach here described on students’ media interactions in adulthood.
Evolution characteristics, carbon emission effects and influencing factors of production-living-ecological space in Taihang Mountain poverty belt, China
Authors: Chen Jing , Zhang Jinying , Du Hui , Zhang Tianmeng
Published: April 2024

The rapid advancement of urbanization and industrialization in China has gradually spread to the poor mountainous areas, which has not only brought about rapid economic development but has also caused the increasing competition for production-living-ecological spaces (PLES) and many ecological and environmental problems, carbon emissions have also increased. As an economically less developed and ecologically fragile area in China, whether the transition of the PLES in the mountain poverty belt has unique characteristics? How the PLES transition in mountainous areas affects carbon emissions and what are the important factors affecting carbon emissions? To explore these issues in depth, we studied the Taihang Mountain area in Shijiazhuang (TMS) using remote sensing image interpretation data from 2000, 2010, and 2020, and we analyzed the PLES evolution characteristics, carbon emission changes, carbon emission effects and its influencing factors of PLES. The results are as follows: 1) The TMS was dominated by ecological and production space. From 2000 to 2020, the production space decreased by 384.66 km2, the ecological space increased by 123.80 km2, and the living space increased by 260.86 km2. Agricultural production space was mainly converted to ecological and rural living space. Industrial and mining productive space was mainly converted to agricultural productive space and urban living space. 2) The study area was in a state of carbon deficit, the transition of ecological space and agricultural productive space to industrial and mining productive space and living space were the main transition types caused the carbon emissions increasing, and that of industrial and mining productive space to agricultural productive space was the main type caused the carbon emissions decreasing. 3) The proportion of construction land, urbanization rate and proportion of secondary industry are the main factors leading to the increase of carbon emissions. Per capita energy consumption, forest coverage and proportion of tertiary industry are the main factors leading to the decrease of carbon emissions. This can provide new ideas for research on carbon emissions from land-use changes and a theoretical basis for the optimization of territorial space in the mountainous areas of China.
KHDRBS1 as a novel prognostic signaling biomarker influencing hepatocellular carcinoma cell proliferation, migration, immune microenvironment, and drug sensitivity
Authors: Fan Rui , Liu Fahui , Gong Qiming , Liu Donghua , Tang Shihang , Shen Dongyan
Published: April 2024

Background

Human tumors pose significant challenges, with targeted therapy against specific molecular targets or signaling pathways being a mainstay alongside surgical resection. Previous studies have implicated KHDRBS1 in the oncogenesis of certain human tumors such as colorectal and prostate cancers, underscoring its potential as a therapeutic target. However, the comprehensive expression pattern of KHDRBS1 in hepatocellular carcinoma (HCC) warrants further exploration.

Methods

Integrating and analyzing multi-omics, multi-cohort data from public databases, coupled with clinical samples and molecular biology validation, we elucidate the oncogenic role of KHDRBS1 in HCC progression. Additionally, leveraging HCC single-cell sequencing data, we segregate malignant cells into KHDRBS1-positive and negative subsets, uncovering significant differences in their expression profiles and functional roles.

Results

Our study identifies KHDRBS1 as a tumor-promoting factor in HCC, with its positivity correlating with tumor progression. Furthermore, we highlight the clinical significance of KHDRBS1-positive malignant cells, aiming to further propel its clinical utility.

Conclusion

KHDRBS1 plays a key role in HCC development. This study provides crucial insights for further investigation into KHDRBS1 as a therapeutic target in HCC.
Relationship between interprofessional collaboration and psychological distress experienced by healthcare professionals during COVID-19: a monocentric cross-sectional study
Authors: Ruttmann Kirstin , Albaladejo-Fuertes Sheila , Lindenberg Nicole , Kunst Claudia , Mehrl Alexander , Kindl Vera , Gülow Karsten , Schlosser-Hupf Sophie , Schmid Stephan , Müller Martina
Published: April 2024

Background

Since the onset of the COVID-19 pandemic, global healthcare systems have faced unprecedented challenges, leading to significant psychological distress among healthcare professionals. Recognizing the importance of enhanced interprofessional collaboration in alleviating this burden, as emphasized by the World Health Organization in 2020, we investigated whether such collaboration could mitigate staff psychological distress during crises. To our knowledge, no study has yet explored the role of interprofessional collaboration as a resilience factor in crises.

Methods

For this monocentric cross-sectional study at a German university hospital, we examined the relationship between the quality of interprofessional collaboration and the psychological distress of healthcare professionals during the initial pandemic wave. We employed validated mental health instruments, such as the GAD-7 and PHQ-2, to assess anxiety and depressive symptoms. Additionally, custom-designed questionnaires evaluated “Pandemic-Associated Burden and Anxiety (PAB; PAA)” and interprofessional crisis management experiences. A novel “Interprofessional collaboration and communication (IPC)” assessment tool was developed based on international competency frameworks, demonstrating strong reliability.

Results

The study involved 299 healthcare professionals (78.6% in direct contact with COVID-19 patients). Moderate levels of PAB/PAA were reported. However, a significant proportion experienced clinically relevant anxiety, as indicated by GAD-7. Negative IPC perceptions correlated with higher levels of psychological distress. Linear regression analysis showed associations between interprofessional collaboration and anxious and depressive symptoms, and pandemic-related burden.

Conclusion

Our findings highlight the vital role of enhanced interprofessional collaboration in strengthening the psychological well-being of healthcare professionals during crises. The study underscores the need to foster a collaborative environment and integrate interprofessional education for resilience.
A proof of concept for a targeted enrichment approach to the simultaneous detection and characterization of rickettsial pathogens from clinical specimens
Authors: Paskey Adrian C. , Schully Kevin L. , Voegtly Logan J. , Arnold Catherine E. , Cer Regina Z. , Frey Kenneth G. , Blair Paul W. , Clark Danielle V. , Ge Hong , Richards Allen L. , Farris Christina M. , Bishop-Lilly Kimberly A.
Published: April 2024

Infection with either Rickettsia prowazekii or Orientia tsutsugamushi is common, yet diagnostic capabilities are limited due to the short window for positive identification. Until now, although targeted enrichment had been applied to increase sensitivity of sequencing-based detection for various microorganisms, it had not been applied to sequencing of R. prowazekii in clinical samples. Additionally, hybridization-based targeted enrichment strategies had only scarcely been applied to qPCR of any pathogens in clinical samples. Therefore, we tested a targeted enrichment technique as a proof of concept and found that it dramatically reduced the limits of detection of these organisms by both qPCR and high throughput sequencing. The enrichment methodology was first tested in contrived clinical samples with known spiked-in concentrations of R. prowazekii and O. tsutsugamushi DNA. This method was also evaluated using clinical samples, resulting in the simultaneous identification and characterization of O. tsutsugamushi directly from clinical specimens taken from sepsis patients. We demonstrated that the targeted enrichment technique is helpful by lowering the limit of detection, not only when applied to sequencing, but also when applied to qPCR, suggesting the technique could be applied more broadly to include other assays and/or microbes for which there are limited diagnostic or detection modalities.
Association between oral microbiome and five types of respiratory infections: a two-sample Mendelian randomization study in east Asian population
Authors: He Jiawei , Mao Ningfeng , Lyu Wenliang , Zhou Shuhan , Zhang Yang , Liu Zhiyi , Xu Zixuan
Published: April 2024

Objective

To explore the causal relationship between the oral microbiome and specific respiratory infections including tonsillitis, chronic sinusitis, bronchiectasis, bronchitis, and pneumonia, assessing the impact of genetic variations associated with the oral microbiome.

Methods

Mendelian randomization was used to analyze genetic variations, leveraging data from genome-wide association studies in an East Asian cohort to identify connections between specific oral microbiota and respiratory infections.

Results

Our analysis revealed that Prevotella, Streptococcus, Fusobacterium, Pauljensenia, and Capnocytophaga play crucial roles in influencing respiratory infections. Prevotella is associated with both promoting bronchitis and inhibiting pneumonia and tonsillitis, with a mixed effect on chronic sinusitis. Streptococcus and Fusobacterium show varied impacts on respiratory diseases, with Fusobacterium promoting chronic sinusitis, bronchiectasis, and bronchitis. Conversely, Pauljensenia and Capnocytophaga are linked to reduced bronchitis and tonsillitis, and inhibited pneumonia and bronchitis, respectively.

Discussion

These findings underscore the significant impact of the oral microbiome on respiratory health, suggesting potential strategies for disease prevention and management through microbiome targeting. The study highlights the complexity of microbial influences on respiratory infections and the importance of further research to elucidate these relationships.