bluuebunny/crossref_metadata_2025 huggingface dataset:
Acupuncture Improves Synaptic Plasticity of SAMP8 Mice through the
RhoA/ROCK Pathway
Authors: Kan Bohong , Dong Zhengjia , Tang Zhenyu , Zhao Lan , Li Zhen
Published: September 2023

Background:

Studies have found synaptic plasticity damage to be an early marker of
Alzheimer's disease (AD). RhoA/ROCK pathway is involved in the regulation of synaptic plasticity.
Acupuncture can significantly improve the cognitive state of AD.

Objective:

We aimed to use modern biological technology to detect the changes in synaptic plasticity
and RhoA/ROCK pathway in SAMP8 mice, as well as the intervention effect of acupuncture.

Methods:

Morris water maze and electrophysiological techniques were used in vivo to detect the
changes in spatial memory and LTP of mice. Golgi Cox staining and CASEVIEWER2.1 software
were used to quantitatively analyze the changes in the morphology and number of dendritic spines
in the hippocampus of mice. The activity of RhoA and ROCK2 in the hippocampus of mice was detected,
respectively, by pull-down technique and ELISA. WB technique was used to detect the protein
expression of ROCK2 and phosphorylation level of MLC2, LIMK2, and CRMP2 in the hippocampus
of mice.

Results:

The neurobehavior and synaptic plasticity of 8-month-old SAMP8 mice were found to be
significantly impaired. Acupuncture could improve the spatial learning and memory ability of
SAMP8 mice, and partially prevent the reduction in the number of spines on the secondary branches
of the apical dendrites in the hippocampus and the attenuation of LTP. The RhoA/ROCK pathway
was significantly activated in the hippocampus of 8-month-old SAMP8 mice, and acupuncture
had an inhibitory effect on it.

Conclusion:

Acupuncture can improve synaptic plasticity by inhibiting the abnormal activation of
the RhoA/ROCK pathway, and improve the spatial learning and memory ability of AD, so as to
achieve the purpose of treating AD
Anti-tumor Mechanism of Camellia nitidissima Based on Network Pharmacology and Molecular Docking
Authors: Wang Jun , Cheng Jingjing
Published: September 2023

Background:

Modern pharmacological research indicated that Camellia nitidissima (CAM) had significant anti-tumor activity, but the investigation of its mechanism was still lacking.

Objective:

The multi-component, multi-target and multi-pathway mechanism of CAM against tumor was investigated based on network pharmacology and molecular docking.

Methods:

The active ingredients and targets of CAM were selected through a literature search, Traditional Chinese Medicine Systems Pharmacology database and PharmMapper database, and tumor-related targets were selected by GeneCards database, then to obtain the anti-tumor related targets of CAM. The protein interaction relationship was obtained through STRING database, protein-protein interaction network was constructed using Cytoscape 3.7.2 software, and enrichment analysis of GO and KEGG was conducted. AutoDock Tools 1.5.6 software was used to verify the molecular docking between the key ingredients and the key targets.

Results:

Catechin, epicatechin and luteolin were identified as the key anti-tumor related ingredients, and ESR1, EGFR, MAPK8, MAPK10, AR, PGR, F2 and PIK3CG were identified as the key targets. The GO entries mainly involved metabolic process, cellular process, response to stimulus, organelle, cytosol, etc. The KEGG enrichment showed that the key pathways included pathways in cancer, prostate cancer, pancreatic cancer, breast cancer, estrogen signaling pathway, MAPK signaling pathway, PI3K-Akt signaling pathway, etc. KEGG pathway maps indicated that the anti-tumor effect of CAM may be mainly achieved by intervening related targets in the following pathways: AR-HSP/AR-AR/PSA/proliferation and evading apoptosis; F2/GPCR/…/ROCK/tissue invasion and metastasis; F2/GPCR/…/Raf/MAPK signaling pathway/proliferation and sustained angiogenesis; EGFR/PI3K-Akt signaling pathway/proliferation, evading apoptosis and sustained angiogenesis; EGFR/Grb2/…/Raf/MAPK signaling pathway/proliferation and sustained angiogenesis; ER/Estrogen signaling pathway/proliferation; PR/PR-COR/Wnts-RANKL/proliferation; oxidative stress (.O₂-, .OH, H₂O₂)/KEAP1/NRF2/.../proliferation and evading apoptosis. The results of molecular docking showed that the key active ingredients had a good binding activity with each key target.

Conclusion:

It was predicted that the main active ingredients of CAM could bind to tumor-related targets, such as receptor and coagulation-promoting factor, scavenge free radicals, and then interfere with the occurrence and development of tumors.
Segmentation of Brain MRI Images using Multi-Kernel FCM EHO Method
Authors: Kollem Sreedhar , Prasad Ch. Rajendra , Ajayan J. , S. Sreejith , Joseph LMI Leo , Krishna Patteti
Published: September 2023

Background:

In image processing, image segmentation is a more challenging task due to different shapes, locations, image intensities, etc. Brain tumors are one of the most common diseases in the world. So, the detection and segmentation of brain tumors are important in the medical field.

Objective:

The primary goal of this work is to use the proposed methodology to segment brain MRI images into tumor and non-tumor segments or pixels.

Methods:

In this work, we first selected the MRI medical images from the BraTS2020 database and transferred them to the contrast enhancement phase. Then, we applied thresholding for contrast enhancement to enhance the visibility of structures like blood arteries, tumors, or abnormalities. After the contrast enhancement process, the images were transformed into the image denoising phase. In this phase, a fourth-order partial differential equation was used for image denoising. After the image denoising process, these images were passed on to the segmentation phase. In this segmentation phase, we used an elephant herding algorithm for centroid optimization and then applied the multi-kernel fuzzy c-means clustering for image segmentation.

Results:

Peak signal-to-noise ratio, mean square error, sensitivity, specificity, and accuracy were used to assess the performance of the proposed methods. According to the findings, the proposed strategy produced better outcomes than the conventional methods.

Conclusion:

Our proposed methodology was reported to be a more effective technique than existing techniques.
Optimal Operation Scheduling of Multi-energy Complementary Systems
Including Offshore Wind Power
Authors: Lu Qiuyu , Yang Yinguo , Zhao Yang , Chen Yue , Xie Pingping
Published: September 2023

Background:

With the rapid development of offshore wind power in China, offshore wind power is accounting for an increasing proportion of the whole installed power generation in China, which put forward higher requirements for operation scheduling of multi-energy complementary systems including offshore wind power. However, existing studies have paid little attention to the complementary output scheduling of multi-energy systems with a high proportion of offshore wind power, this phenomenon is not conducive to the realization of reasonable operation scheduling.

Objective:

To realize the reasonable operation scheduling of multi-energy systems with a high proportion of offshore wind power.

Methods:

Firstly, the output characteristics of offshore wind power were analyzed and summarized, and modeling was conducted from the perspectives of time distribution, spatial correlation, volatility and randomness, which would serve as the theoretical basis for subsequent researches. Secondly, the complementary rule among offshore wind power and the multi-energy system was analyzed, and the complementary characteristic index was put forward. Then the safety operation was taken as the constraint, and the two-stage operation model of the integrated energy system was established, which considers the auxiliary service costs. In the first stage, the initial generation scheduling was developed according to the day-ahead forecast values of the offshore wind power; in the second stage, the more accurate intra-day operation scheduling was further achieved by considering the intra-day forecast values of offshore wind power and the day-ahead scheduling results. Costs of rotating reserve capacity could be reduced by correcting the deviation of generating capacity, then the revenue-maximizing scheduling strategies were obtained and the output of the pumped-storage power plants was optimized.

Results:

The effectiveness of the model proposed in this paper was verified based on the simulation examples. Compared with the traditional scheduling strategy, the scheduling strategy considering auxiliary service cost proposed in this paper can promote the consumption of offshore wind power, reduce the wind curtailment proportion and improve the electricity sales revenues in the end.

Conclusion:

The research results in this paper provide a reference for the reasonable consumption of multi-energy complementary systems with a high proportion of offshore wind power and improving electricity sales revenues
Banten Governor Election 2017: Jawara, Ulama, and the Absence of Political Identity
Authors: Prasetyawan Wahyu
Published: September 2023

The study aims to evaluate the election of the governor of Banten in 2017. Two candidates follow this governor's election, and both are Muslims. The study uses data from the BPS and KPU at the village level. The analysis method used in this analysis is logistic regression with the acquisition of voices into dependent variables, and the independent variable consists of social and economic groups. The findings of this study show that identity political behavior does not exist in the election of the governor in Banten. The result of this governor's election can be explained more by the behavior of the election based on the economy.
Evaluating a Novel Infant Heart Rate Detector for Neonatal Resuscitation Efforts: Protocol for a Proof-of-Concept Study
Authors: Abdou Abdelrahman , Krishnan Sridhar , Mistry Niraj
Published: September 2023

Background

Over 10 million newborns worldwide undergo resuscitation at birth each year. Pediatricians may use electrocardiogram (ECG), pulse oximetry (PO), and stethoscope in determining heart rate (HR), as HR guides the need for and steps of resuscitation. HR must be obtained quickly and accurately. Unfortunately, the current diagnostic modalities are either too slow, obtaining HR in more than a minute, or inaccurate. With time constraints, a reliable robust heart rate detector (HRD) modality is required. This paper discusses a protocol for conducting a methods-based comparison study to determine the HR accuracy of a novel real-time HRD based on 3D-printed dry-electrode single-lead ECG signals for cost-effective and quick HR determination. The HRD’s HR results are compared to either clinical-grade ECG or PO monitors to ensure robustness and accuracy.

Objective

The purpose of this study is to design and examine the feasibility of a proof-of-concept HRD that quickly obtains HR using biocompatible 3D-printed dry electrodes for single-lead neonatal ECG acquisition. This study uses a novel HRD and compares it to the gold-standard 3-lead clinical ECG or PO in a hospital setting.

Methods

A cross-sectional study is planned to be conducted in the neonatal intensive care unit or postpartum unit of a large community teaching hospital in Toronto, Canada, from June 2023 to June 2024. In total, 50 newborns will be recruited for this study. The HRD and an ECG or PO monitor will be video recorded using a digital camera concurrently for 3 minutes for each newborn. Hardware-based signal processing and patent-pending embedded algorithm-based HR estimation techniques are applied directly to the raw collected single-lead ECG and displayed on the HRD in real time during video recordings. These data will be annotated and compared to the ECG or PO readings at the same points in time. Accuracy, F1-score, and other statistical metrics will be produced to determine the HRD’s feasibility in providing reliable HR.

Results

The study is ongoing. The projected end date for data collection is around July 2024.

Conclusions

The study will compare the novel patent-pending 3D-printed dry electrode–based HRD’s real-time HR estimation techniques with the state-of-the-art clinical-grade ECG or PO monitors for HR accuracy and examines how fast the HRD provides reliable HR. The study will further provide recommendations and important improvements that can be made to implement the HRD for clinical applications, especially in neonatal resuscitation efforts. This work can be seen as a stepping stone in the development of robust dry-electrode single-lead ECG devices for HR estimations in the pediatric population.

International Registered Report Identifier (IRRID)

DERR1-10.2196/45512
Validation of a Brief Internet-Based Self-Report Measure of Maladaptive Personality and Interpersonal Schema: Confirmatory Factor Analysis
Authors: Kim Hyeonseong , Jeong Seohyun , Hwang Inae , Sung Kiyoung , Moon Woori , Shin Min-Sup
Published: September 2023

Background

Existing digital mental health interventions mainly focus on the symptoms of specific mental disorders, but do not focus on Maladaptive Personalities and Interpersonal Schemas (MPISs). As an initial step toward considering personalities and schemas in intervention programs, there is a need for the development of tools for measuring core personality traits and interpersonal schemas known to cause psychological discomfort among potential users of digital mental health interventions. Thus, the MPIS was developed.

Objective

The objectives of this study are to validate the MPIS by comparing 2 models of the MPIS factor structure and to understand the characteristics of the MPIS by assessing its correlations with other measures.

Methods

Data were collected from 234 participants who were using web-based community sites in South Korea, including university students, graduate students, working professionals, and homemakers. All the data were gathered through web-based surveys. Confirmatory factor analysis was used to compare a single-factor model with a 5-factor model. Reliability and correlation analyses with other scales were performed.

Results

The results of confirmatory factor analysis indicated that the 5-factor model (χ2550=1278.1; Tucker-Lewis index=0.80; comparative fit index=0.81; and Root Mean Square Error of Approximation=0.07) was more suitable than the single-factor model (χ2560=2341.5; Tucker-Lewis index=0.52; comparative fit index=0.54; and Root Mean Square Error of Approximation=0.11) for measuring maladaptive personality traits and interpersonal relationship patterns. The internal consistency of each factor of the MPIS was good (Cronbach α=.71-.88), and the correlations with existing measures were statistically significant. The MPIS is a validated 35-item tool for measuring 5 essential personality traits and interpersonal schemas in adults aged 18-39 years.

Conclusions

This study introduced the MPIS, a concise and effective questionnaire capable of measuring maladaptive personality traits and interpersonal relationship schemas. Through analysis, the MPIS was shown to reliably assess these psychological constructs and validate them. Its web-based accessibility and reduced item count make it a valuable tool for mental health assessment. Future applications include its integration into digital mental health care services, allowing easy web-based administration and aiding in the classification of psychological therapy programs based on the obtained results.

Trial Registration

ClinicalTrials.gov NCT05952063; https://www.clinicaltrials.gov/study/NCT05952063
Health Information on Pre-Exposure Prophylaxis From Search Engines and Twitter: Readability Analysis (Preprint)
Authors: Park Albert , Sayed Fatima , Robinson Patrick , Elopre Latesha , Ge Yaorong , Li Shaoyu , Grov Christian , Sullivan Patrick Sean
Published: September 2023

BACKGROUND

Pre-exposure prophylaxis (PrEP) is proven to prevent HIV infection. However, PrEP uptake to date has been limited and inequitable. Analyzing the readability of existing PrEP-related information is important to understand the potential impact of available PrEP information on PrEP uptake and identify opportunities to improve PrEP-related education and communication.

OBJECTIVE

We examined the readability of web-based PrEP information identified using search engines and on Twitter. We investigated the readability of web-based PrEP documents, stratified by how the PrEP document was obtained on the web, information source, document format and communication method, PrEP modality, and intended audience.

METHODS

Web-based PrEP information in English was systematically identified using search engines and the Twitter API. We manually verified and categorized results and described the method used to obtain information, information source, document format and communication method, PrEP modality, and intended audience. Documents were converted to plain text for the analysis and readability of the collected documents was assessed using 4 readability indices. We conducted pairwise comparisons of readability based on how the PrEP document was obtained on the web, information source, document format, communication method, PrEP modality, and intended audience, then adjusted for multiple comparisons.

RESULTS

A total of 463 documents were identified. Overall, the readability of web-based PrEP information was at a higher level (10.2-grade reading level) than what is recommended for health information provided to the general public (ninth-grade reading level, as suggested by the Department of Health and Human Services). Brochures (n=33, 7% of all identified resources) were the only type of PrEP materials that achieved the target of ninth-grade reading level.

CONCLUSIONS

Web-based PrEP information is often written at a complex level for potential and current PrEP users to understand. This may hinder PrEP uptake for some people who would benefit from it. The readability of PrEP-related information found on the web should be improved to align more closely with health communication guidelines for reading level to improve access to this important health information, facilitate informed decisions by those with a need for PrEP, and realize national prevention goals for PrEP uptake and reducing new HIV infections in the United States.
Diagnosis, treatment and monitoring of patients with primary malignant tumors of the bones of the pelvis and lower extremities: promising technologies
Authors: Drobotun O.V.
Published: September 2023

Background. Diagnosis and treatment of patients with malignant bone tumors requires continuous improvement of existing methods of diagnosis and treatment. Purpose: to improve the treatment results in patients with tumors of the femur and pelvis through the application of medical imaging technologies, 3D modeling and 3D printing of personalized models of bones and tumors, arthroplasty and bioactive ceramics. Materials and methods. Examination, treatment and monitoring of 28 patients with malignant tumors of the bones of the pelvis, lower extremities and examination of 16 apparently healthy people were performed. Computed tomography (CT) and magnetic resonance imaging (MRI), 3D modeling, biochemical markers of bone metabolism, arthroplasty, biomine were applied. Results. The technology of creating a 3D model of bones affected by malignant tumors has been developed based on the results of MRI, CT and 3D printing. Preoperative planning and training on 3D models reliably reduced intraoperative blood loss, duration of surgery, time of complete recovery of the extremity function, the risk of postoperative complications and, accordingly, increased the duration of the first recurrence-free period. The use of bone resorption and osteosynthesis markers allows to control the osseointegration of endoprosthesis and biomine, to diagnose recurrence/metastasis timely. Conclusions. The application of CT + MRI + 3D modeling + training on 3D models + tumor removal + arthroplasty + biomine algorithm provided functional results after 12 months: excellent — in 57.35 %, good — in 29.41 % of cases. Postoperative complications were observed only in 12.2 % of patients, local recurrences — in 7.3 %.
Productividad científica de investigadores de la Universidad Nacional de Asunción (UNA): comprobación del modelo de Lotka
Authors: Sena Correa Emilce , Lascurain María Luisa , Cáceres Ruiz Díaz Mariana , Pineda Alvarenga Johana Raquel
Published: September 2023

Este trabajo plantea la comprobación del modelo sobre productividad de los autores propuesto por Lotka. En su forma generalizada, para los investigadores de la Universidad Nacional de Asunción que publicaron entre los años 2015 y 2020 en revistas paraguayas recogidas en SciELO particularmente en las áreas de Ciencias Médicas y de la Salud, Ciencias Sociales, Ciencias Veterinarias y Agrícolas. Se recuperaron un total de 627 documentos incluidos en 15 títulos de revista. En las cuatro áreas de estudio se comprueba el ajuste de la producción de los autores al postulado de Lotka con una importante proporción de autores esporádicos. El análisis demuestra la posibilidad de comprobación del modelo en distintas áreas científicas en un periodo inferior a los 10 años.
PEMBELAJARAN SUMPAH PEMUDA DAN PENDIDIKAN KARAKTER GUNA MEWUJUDKAN PROFIL PELAJAR PANCASILA
Authors: Azmi Inez Kalyana
Published: September 2023

Artikel ini berupaya untuk menganalisis peristiwa Sumpah Pemuda dan kaitannya dengan pendidikan karakter untuk mewujudkan profil pelajar Pancasila. Sumpah Pemuda identik dengan kongres dan ikrar yang dicetuskan. Dewasa ini banyak terjadi permasalahan di kalangan pemuda bangsa, seperti degradasi moral, lunturnya karakter jiwa pemuda bangsa, dan timbulnya konflik antarpemuda dikarenakan adanya perbedaan. Di sisi lain, pemerintah juga telah mempunyai visi misi untuk meningkatkan kualitas sumber daya manusia Indonesia melalui bidang pendidikan dengan mencetuskan Profil Pelajar Pancasila, hal tersebut merupakan salah satu cara untuk menciptakan pelajar Indonesia yang berkarakter dan berdaya guna untuk kemajuan negara. Oleh sebab itu, penulis menggunakan pendekatan kualitatif secara deskriptif. Pengumpulan sumber data dilakukan dengan mengakses artikel ilmiah dan telaah kajian kepustakaan kemudian di deskripsikan dengan menggunakan kalimat sederhana yang komunikatif. Hasil dari telaah kajian yang dilakukan ialah dapat mengetahui relevansi pembelajaran sumpah pemuda dengan pendidikan karakter dan pelajar pancasila, mampu memahami sejarah peristiwa Sumpah Pemuda, menjelaskan tentang pendidikan karakter dalam pembelajaran, dan menganalisis karakteristik profil pelajar Pancasila.
Preferensi Hijauan Pakan Gajah Sumatera (Elephas maximus sumatranus): Studi Kasus di Kawasan Seblat
Authors: Syarifuddin Hutwan
Published: September 2023

The    research    has    purposed  were  to  know forages of  the  gajah  Sumatera    (Elephas  maximus sumatranus)  preference.  Data  primer    was  calculated  with    direct  method  in  field  with    vegetation analysis.  The  result    showed    that most  fodder    types  were   Air  Tenang  (225).  Air  Senaba  and  Air Sabai  (215)  were similar.  Batu  Ampar    (213),  Simpang  Tiga    (207). Air  Riki  was lowest    (197).  The sum    of    elephant  forages  were in Air  Tenang    (70  types),  Air  Senaba  (67    types),  Simpang  Tiga  (66  types), Air Sabai (64 types), Air  Riki (63   types)  and  Batu Ampar  (59   types). The forages type    was liked  as:  Colocasia  gigantea,  Imperata  cylindrica,  Cynodon  dactylon   and  Ichnanthus  vicinus, Angiopteris  avecta,   Knema  sp,  Macaranga  gigantea,  Macaranga  pruinosa, Parkia  speciosa,  Mallotus paniculatus, and  Arthocarpus elasticus.
Pengaruh Probiotik Dan Trichorderma Terhadap Hara Pupuk Kandang Yang Berasal Dari Feses Sapi Dan Kambing
Authors: S Suhesy , A Adriani
Published: September 2023

The aim of this study was to investigate the best standard procedure to produce a good nutrient bio-fertilizer from with the basic ingredient cow and goat faeces and probiotic and Trichoderma. The design of this experiment was Completely Randomized Design in factorial arrangement (3x3x4) with the factor A, the animal feces, and the factor B, probiotic and Trichoderma, and four replications. For factor A, there were 100% goat feces, 50% cow feces and 50% goat feces + 50% cow feces for A1, A2 and A3 respectively and for factors B there were 5% probiotic, 5% Tricoderma and 2.5% probiotic + 2.5% Tricoderma for B1, B2 and B3 respectively. Parameters measured were pH, the content of N, P, K and C/N ratio. Results of this experiment showed that the fertilizer originated from goat feces consisted of more nutrient than those from cow feces. The mix of both probiotic and Trichoderma was the good activator in producing biofertilizer. The average content of P was 0.68% with the range of 0.39 – 0.96%. The average content of K was 1.97% with the range of 0.60 – 1.78%. The average content of C was 19.51% with the range of 13.53 – 27.07%. The ratio of C/N was 11.89 with the range of 8.54 – 18.22. It could be concluded that the best chemical composition in this study was fertilizer originated from goat feces mixed with probiotic and Trichoderma as activator.
Sifat-sifat Fisik Sosis Berbahan Baku Surimi-like Daging Kambing dengan Menggunakan Susu Kedelai Sebagai Binder
Authors: Mega Olfa , S Suharyanto , Badarina Irma
Published: September 2023

The purpose of this study was to evaluated physical properties of sausage made from meat goat surimi-like as affected by using soya milk as binder. The study was designed as block randomized design at four treatments and three replications included on the block, those were 0% ,2%, 4% and 6% soya milk as substitusion skim milk. The amount of binder was 6% of meat. weight. Data were analyzed using analysis of variance and Duncan Multiple of Range Test. The results showed that using soya milk as binder significantly (P<0,01) decreased pH, firmness and cooking loss, while water holding capacity of sausage increased. Using soya milk 6% as binder improve water holding capacity, cooking loss and fimness.
Pengaruh modifikasi inokulum Feses Sebagai Pengganti Cairan Rumen Pada Teknik In Vitro : Estimasi Kecernaan NDF, ADF dan Protein Kasar Rumput lapangan
Authors: Afdal M , Yurleni Y
Published: September 2023

Tujuan penelitian ini adalah untuk mengetahui potensi inokulum feses yang ditambahkan gula dan urea sebagai inokulan dalam teknik in vitro dalam menentukan kecernaan Neutral Detergent Fibre (NDF), Acid Deteegent Fibre (ADF) dan protein kasar (PK) rumput lapangan. Penelitian ini menggunakan seperangkat alat in vitro dua langkah dan seperangkat peralatan untuk analisis NDF, ADF dan PK. Inokulum rumen dan feses diambil dari sapi yang sama sebelum sapi diberi makan pada jam 07.00. Feses diperas untuk mendapatkan inokulum dan ditambahkan dengan gula dan atau urea sesuai dengan perlakuan. Perlakuan terdiri dari A. Inokulum rumen (kontrol), B. Inokulum feses, C. Inokulum feses dan 2,5 % gula, D. Inokulum feses, 2,5 % gula dan 2,5 % urea dan E. Inokulum feses dan 2,5 % urea. Penelitian ini menggunakan Rancangan Acak Lengkap (5x4) dengan lima perlakuan dan setiap perlakuan dikenakan 4 kali ulangan. Kecernaan NDF, ADF dan PK perlakuan A yang memakai inokulum rumen juga menunjukkan kecernaan yang lebih tinggi dari pada perlakuan lain, B, C, D dan E yang memakai inokulum feses dengan berbagai modifikasi penambahan gula maupun urea.
Photocatalytic degradation of methylene blue by anatase TiO 2 coating
Authors: Desch Nikolai , Rheindorf Angela , Fassbender Cornelia , Sloot Marc , Lake Markus
Published: September 2023

Photocatalytic coatings have the potential to contribute to the
purification of water via an advanced oxidation process (AOP) [1]. A
commonly used method for analyzing the mechanism of the photocatalytic
performance of a given reactor type is to document the degradation
behavior in a solution containing methylene blue. However, since
methylene blue is rather unstable, the degradation results should be
viewed critically. In this work, the degradation behavior of a test
solution with methylene blue on quartz glass surfaces coated with
photocatalytic titanium dioxide (TiO ) of the anatase
modification was investigated through a variety of different light
sources. The coating was deposited by the reactive pulsed DC magnetron
sputtering (MSIP-PVD) method described in [2], while the quartz
glasses were coated with a 100 nm thick TiO coating.
The same glasses were used for all experiments with TiO
. In the determination of the degradation rate,
additional experiments were performed using pure quartz glass without
any coating, which made it possible to examine the influence of
different light sources on the degradation rate of methylene blue in
general. Three different light sources, namely UV-A, UV-C, and simple
fluorescent lamps were used in this study. The concentration of
methylene blue was recorded by photo spectrometer in 10-minute
increments throughout the experiment and the experiments were performed
for 24 hours in all cases.
The future of ecological research will not be (fully) automated
Authors: Poisot Timothée , Riva Giulio Dalla , Desjardins-Proulx Philippe , Luccioni Alexandra Sasha
Published: September 2023

The recent year has seen the creation of large-scale generative
Artificial Intelligence (AI) systems like GPT-4 and LaMDA, which are
generating increasingly plausible outputs ranging from reasonable
answers to questions, images of well-known people or situations, and
convincing conversational exchanges. The most well-known language model,
ChatGPT, is raising concerns across all scientific fields, leading to
calls for its regulation (Hacker 2023). In this viewpoint, we explore
how generative language models interact with the specificities of
ecology’s epistemologies.
2023 Trade Finance Gaps, Growth, and Jobs Survey
Authors:   Asian Development Bank, Beck Steven , Tayag Mara Claire ,   Asian Development Bank, Kim Kijin ,   Asian Development Bank, Latoja Ma. Concepcion ,   Asian Development Bank, Pandey Ankita ,   Asian Development Bank, Malaket Alexander ,   Asian Development Bank
Published: September 2023

Drawing on 2023 survey results, this brief analyzes the widening global trade finance gap, shows why higher financing costs are posing a challenge to companies, and assesses the shift toward trade digitalization and sustainable finance. Based on responses from hundreds of banks and corporates worldwide, it assesses supply chain issues, and shows how credit tightening and geopolitical uncertainty are affecting bank trade finance portfolios. It recommends ways to push forward the global digitalization agenda, harmonize sustainability standards, and expand capacity to help attract new pools of capital, drive financing to small and medium-sized enterprises, and narrow the trade finance gap.
A Study of Meaning Constructing of Young Children with Jeju Haenyeo Picture Book
Authors:   Regional Entrepreneurship Education Research Center, Lee Hyuo-Won
Published: September 2023

Purpose: This study examines the process of constructing the meaning of a picture book for young children revealed in the situation of reading a picture book with Jeju haenyeo as the main character. Method: The participants were children aged 4 to 5 years old, and for 8 times in February 2023, they read picture books with researchers and teachers. Results: The children explored the cover of the picturebook, guessed the title, and changed the words and pictures into terms they knew to understand the contents in detail. And after interpreting the picture book in connection with what they knew and experienced, they enjoyed the picture book and realized the meaning of Jeju culture and sustainable life practiced by haenyeo. Conclusion: To understand picture books, young children brought their own prior knowledge, and after grasping the contents of picture books through the interpretation community, it was found that they enjoyed it.
Development of Parent Education Program Prototype Using Action Learning for Cultivation of Young Children Character
Authors:   Regional Entrepreneurship Education Research Center, Lee Jeong-Mi
Published: September 2023

Purpose: The purpose of this study is to develop a prototype of an action learning parent education program for character development of children. Method: First, literature and cases related to early childhood personality, parent education, and action learning were analyzed, and a demand survey was conducted through in-depth interviews. Based on this, the components of the program were extracted, drafts were prepared, and the final program was derived through focus group interviews (FGI) and expert reviews. Results: The core activity process is divided into eight stages: lecture → Team building & Developing problems → Exploring and clarifying problems → Deriving possible solutions → Making action Plan → Implementing → Reflecting → Post-Activity. Conclusion: Through this study, it is expected to help solve practical problems for the character development of young children. This program is designed as a prototype of an action learning parent education program for character development of children, and it is necessary to verify the effectiveness by applying an actual program based on the program completion plan.
Contextual teaching and learning handout on food digestive system materials
Authors: Nadira Asmaul , Lodang Hamka , Saleh Andi Rahmat
Published: September 2023

Education is the key to improving the condition of society, because the aim is to educate and develop all existing potential. Its implementation involves many parties in order to achieve educational goals properly. This research was conducted to contribute to these educational goals, specifically to develop handouts based on contextual teaching and learning. This development uses the ADDIE model (Analyze, Design, Develop, Implement, Evaluate). Researchers develop handouts that have been validated beforehand. This validation process uses several questionnaires by experts. In addition, other instruments have also been designed, in the form of teacher and student response questionnaires. After implementation, the research product was evaluated by analyzing data for validity and practicality. The results of the study show the validity value with an average of 4.22 in the valid category, while the responses of teachers and students are included in the very practical category with an average of 89.12%.
Need analysis of a vertebrate electronic atlas as a biology instructional media
Authors: Ardiana Rinata
Published: September 2023

The purpose of this study was to analyze the needs of teachers and students in develop vertebrate e-atlas as biology learning media on animalia material. Based on the first step of the ADDIE development model, analysis, the requirements analysis is conducted. The study was done to find out the problems regarding the learning media used and what media are needed. 24 students from the class X IPA 3 served as the study's subjectsand 1 biology teacher at SMA Panca Marga 1 Lamongan. Guidelines for interviews and questionnaires served as the research instruments. The data analysis method employed descriptive analysis of the interview findings and sought the mean of the questionnaire responses, which were then qualitatively characterized. The results of the needs analysis obtained from interviews with biology teachers stated that it is very necessary to develop a vertebrate e-atlas to provide a variety of existing learning media. The results of the analysis of student needs showed that as many as 92.8% of students found it easier to absorb subject matter using instructional media and as many as 85.7% of students were interested in developing e-atlas vertebrate learning media as biology learning media in animalia material. It may be inferred from the research that there is a need to develop vertebrate e-atlas media in learning biology, especially in animalia material.
VISUAL ANALYSIS PUPPET OF “SI UNYIL” FILM AS INDONESIAN CULTURAL IDENTITY
Authors: Mulyana Agus Rahmat , Dewi Agustina Kusuma , Setiawan Sulistyo
Published: September 2023

"Si Unyil" is a television series for Indonesian children, created by Suyadi and in production by the National Film Production Center (PPFN).  "Si Unyil" belongs to the hand puppets category, consisting of the head, body, and hands. The attraction of the film "Si Unyil" lies in the facial expressions of the doll called Wanda, and is supported by the strength of the story contains elements of humor, joy, tension, to sadness. This study uses a semiotic approach that focuses on the analysis of Wanda "Si Unyil", as the central character in the film "Si Unyil"; and several supporting characters in the film, i.e. Pak Raden, Pak Ogah, Cuplis, and Meilani. Wanda can represent certain facial characters for certain roles in certain storylines. Therefore, Wanda can carry comprehensive meanings that indicate emotional conditions, physical conditions, and environmental conditions. Analysis of "Si Unyil" through the visual of the puppet, concluded that "Si Unyil" contains educational values, morals, and social ethics that are displayed in various daily activities, through dialogue and the behavior between "Si Unyil" and his friends. "Si Unyil" film also possible to be a representation of the Indonesian people, which is guided by the ideology of Pancasila.
Mul'tidisciplinarnyj podhod k lecheniyu pacienta s nerezektabel'nym metastaticheskim porazheniem pecheni HER2+ adenokarcinomoj zheludka
Authors: Коломиец К. В. , Исаев И. В. , Ковалев В. В. , Грищенко Н. В. , Коковихина Д. И. , Морозова А. А. , Торосян А. Р. , Шашкова В. В. , Снегирева П. В.
Published: September 2023

U 85% bol'nyh vo vsem mire srazu ili v techenie trekh let rak zheludka (RZH) perekhodit v metastaticheskuyu formu. Pechen' yavlyaetsya organom metastazirovaniya RZH s chastotoj 30–50%, vklyuchaya kak sinhronnye, tak i metahronnye metastazy. Pri nalichii mul'tifokal'nyh metastazov pecheni prognoz dlya pacientov ves'ma neblagopriyaten: mediana vyzhivaemosti sostavlyaet okolo 10–15 mesyacev, a trekhletnyaya vyzhivaemost' — menee 10%, i palliativnym variantom lecheniya v takih sluchayah yavlyaetsya sistemnaya himioterapiya. Vnedrenie otnositel'no molodogo lokal'nogo metoda vozdejstviya na metastaticheskie ochagi — transarterial'noj himioembolizacii (TAHE) v kombinacii s immunoterapiej otkrylo novye vozmozhnosti lecheniya metastazov v pechen'. Predstavlen klinicheskij sluchaj ispol'zovaniya metodiki TAHE v kombinacii s immunoterapiej, a takzhe himioterapiej u pacienta pri nerezektabel'nom metastaticheskom porazhenii pecheni HER2+ adenokarcinomoj zheludka s prodolzhitel'nost'yu zhizni 42 mesyaca s momenta ustanovleniya diagnoza.
Correlation Between Students' Self-Efficacy Level and Their Speaking Achievement
Authors: Yuliantari Shinta , Femilia Praptika Septi
Published: September 2023

English Educational students should have good or even high speaking ability because they are English teacher candidates who are expected to be able to speak English very well. They will speak English a lot when they become teachers later. If they have a low speaking ability, there might be a misunderstanding and them and their students. This study aims to determine if there is a positive correlation between the self-efficacy of English students and their speaking skills. The research utilized a correlational examination plan to examine the students' self-efficacy. The study used the self-efficacy Questionnaire and the speaking test for the 6th-semester English students of UIN KHAS. The sample size was composed of 137 students and used the Slovin formula. The sample total in this research is 34 consisting of 7 males and 27 females. Instrument Instruments for this research are a speaking test and a questionnaire. The information was examined using Statistical Package for Social Sciences (SPSS) 16.0 program. Researchers utilized the Pearson product-moment correlation to discover the correlation result. The correlation result is r count = 0.848, and the significance value is ρ = 0.000. The r table for N = 34 is 0.329. Therefore, the r count is more than the r table (0.848 > 0.329), indicating a strong correlation. In addition, the significance value is less than 0.05 (0.000 < 0.05). Therefore, the null hypothesis (Ho) is rejected, and the alternative hypothesis (Ha) is accepted.
STUDENTS AND TEACHERSâ€™ PERCEPTIONS CONCERNING SMARTPHONE USAGE IN EFL LEARNING
Authors: Pale Erlinda Sonya , Luruk Fransiska Densiana , Seran Primus , Leda Leu Aloysia Trivonia
Published: September 2023

The infancy of research on junior high school students and English teachers in the border areas concerning the implementation of smartphones in English learning triggered the researchers to conduct a study to deal with the phenomenon. Hence, a recent study was undertaken to acquire the following goals. 1) to identify the level of smartphone utilization as a medium of learning English at SMP Satap Sono and SMPN Napan. 2) to know the perception of the students and English teachers of SMP Satap Sono and SMPN Napan towards using smartphones as a medium for learning English. This study embraced 60 participants comprising 30 students from SMPN Napan and 30 from SMPN Sono, as well as 3 English teachers from the two schools. The research design applied was qualitative descriptive. To procure data, the researchers applied three instruments: questionnaires, interviews, and class observation. The researchers observed the learning process in which English teachers and students incorporated smartphones, distributed questionnaires to the students and the English teachers, and interviewed the students and the English teachers concerning the implementation of smartphones as a medium in English learning. Further, the data were scrutinized by a descriptive method. Research results signified that the level of using the smartphone in learning English for the students and English teachers in SMP Satap Sono and SMPN Napan was categorized as low. On the contrary, the English teachers and the students had positive perceptions of the application of smartphones to support English learning. Then, the current study could inform the English teachers at the two schools on how their students perceive the integration of smartphones. Henceforth, it is expected that the subsequent researchers could explore a variety of English learning applications to be applied by the students and teachers at the border area.
The use of the R2 coefficient of determination to determine the impact of selected parameters on the number of fatalities in road accidents in Poland compared to selected European countries in 2010-2020
Authors: Frej Damian
Published: September 2023

The article presents statistical data on the state of road transport safety in Poland against the background of selected European countries in the years 2010-2020. The article presents the characteristics of the change in the length of motorways along with the percentage rate of increase in the length of motorways in selected European countries. Statistical data on the number of registered motor vehicles in Poland against the background of selected European countries in the analyzed period are presented. The main purpose of the article is to use the coefficient of determination R2 to determine the impact of the number of registered motor vehicles and the length of motorways on the number of fatalities in road accidents in selected European countries. The authors chose the coefficient of determination R2 as an indicator of how reducing the overall number of road accidents and increasing the length of motorways will affect the number of fatalities. The coefficient of determination is used to determine what percentage of one variable affects the variability of the other variable. The determined high value of the determination index R2 (close to 1) indicates a large impact of the analyzed variable on the number of fatalities in road accidents. The high result of the determination coefficient R2 for Poland in terms of the analyzed variables confirms that a further reduction in the number of fatalities in road accidents is possible thanks to the expansion of motorways and the reduction of the number of motor vehicles.
Disturbance of Trains Movement under the ERTMS Control System
Authors: Sumiła Marek
Published: September 2023

The article presents a discussion leading to the identification the possible causes of disturbances in train movements under the supervision of the European Rail Traffic Management System ERTMS. As a consequence of detected events, unintentional initiation of a train braking procedure occurs despite the absence of objective reasons for such behaviour. In essence, the paper presents the ERTMS as a real-time system based on the two subsystems ETCS and GSM-R. Each of these subsystems includes a vehicle part and an infrastructure part. The article starts by identifying general considerations that may affect the lack of compatibility between vehicle and trackside infrastructure as a result of changes in versions of the specification (baseline). The following part of the article reviews the process leading to train braking is reviewed. The next part of the article refers to ETCS scenarios and parameters affecting the system response during operation. It referred to the considerations of message transmission between the ETCS ground infrastructure and the vehicle via the telecommunications network, including the GSM-R. The final section focuses on the causes and consequence of the overlap of the RBC's and GSM-R radio cells boundaries. The article concludes with a brief summary and conclusions.
Cuidar bajo tierra. La experiencia de mujeres cuidadoras que laboran en la economía popular dentro del Metro de la Ciudad de México
Authors: Reynaga Alma Arvizu , Estrada Gutiérrez Flor  Daniela
Published: September 2023

En este artículo analizamos la combinación de trabajo de cuidados y trabajo remunerado que realizan las mujeres conocidas como vagoneras, quienes laboran como vendedoras dentro de los trenes del Sistema de Transporte Colectivo (STC) Metro de la Ciudad de México. Nuestro análisis es resultado de dos trabajos etnográficos desarrollados entre 2020 y 2022, en los que desempeñamos observación, observación participante y entrevistas en profundidad con once vagoneras de entre 17 y 53 años. Como principales resultados encontramos que estas mujeres suelen ser madres solteras que eligen estas actividades ante las pocas posibilidades que tienen en el mercado de trabajo formal de compaginar el cuidado y crianza de sus hijas o hijos. La mayoría son acompañadas por los menores durante sus jornadas de venta, pues no cuentan con una red de apoyo familiar segura que pueda hacerse cargo de ellos, ni con la posibilidad económica para pagar estancias infantiles o escuelas de jornadas extendidas. Debido a lo anterior, las autoridades del Metro y de la Ciudad de México han malinterpretado el acompañamiento de los infantes como trabajo infantil y han ejecutado operativos de detención que, muchas veces se llevan a cabo con violencia y afecta a las madres y a los menores.
1973 y las “alternativas” en el peronismo revolucionario. Las posiciones de la corriente alternativista frente a las coyunturas de apertura electoral, la primavera camporista y su desarticulación
Authors: Stavale Mariela
Published: September 2023

El siguiente artículo se propone volver sobre el año 1973, con el objetivo de relevar analíticamente las posiciones de un sector disonante al interior del peronismo revolucionario: el alternativismo. Hemos propuesto analizar sus posturas en diferentes coyunturas: el período pre-electoral y la apertura democrática en el contexto del Gran Acuerdo Nacional (GAN); el triunfo del Frejuli, la “primavera camporista” y los sentidos revolucionarios que signaron a su programa de gobierno y, finalmente, su derrumbe. Nuestro interés radica en visibilizar las posiciones de sus actores, comparativamente menos conocidos al interior del peronismo revolucionario, pero con propuestas diferentes tanto respecto de las elecciones de marzo, como del regreso del peronismo al gobierno y los primeros meses de gestión.