bluuebunny/crossref_metadata_2025 huggingface dataset:
Inter-individual variation in adaptive capacity at onset of lactation: Linking metabolic phenotype with mitochondrial DNA haplotype in Holstein dairy cows
Authors: Kinoshita Asako , Kenéz Ákos , Hasselmann Martin , Dänicke Sven , Huber Korinna
Published: October 2018

Modern-day dairy cows express great variation in metabolic capacity to adapt to the onset of lactation. Although breeding programs increased the breeding value for longevity and robustness in the sires, a respective phenotype in female offspring has not been improving as predicted. Fundamental energy generating pathways such as mitochondrial fatty acid oxidation might have a crucial role for robustness and metabolic efficiency in dairy cows. Therefore, mitochondrial enzyme expression was examined in liver samples of one set of animals before and after calving. Furthermore, the mitochondrial DNA sequence was determined for each individual of a second set of animals using liver samples. Results from the first trial indicate that the expression and extent of phosphorylation of acetyl-CoA carboxylase (ACC) is the major key step for modulating fatty acid flux into the mitochondria at early onset of lactation in Holstein dairy cows. In the second trial, mitochondrial DNA sequencing and identification of mutation patterns yielded three major haplotypes. Haplotype H2 was closely associated with liver fat content, plasma glycerol and acyl-carnitine concentrations. The mitochondrial DNA haplotype, which is a feature of the maternal lines, might be related to the inter-individual variation in metabolic capacity of Holstein dairy cows.
HPV16-Immortalized Cells from Human Transformation Zone and Endocervix are More Dysplastic than Ectocervical Cells in Organotypic Culture
Authors: Deng Han , Hillpot Eric , Mondal Sumona , Khurana Kamal K. , Woodworth Craig D.
Published: October 2018

A major risk factor for cervical cancer is persistent infection with high-risk human papillomaviruses (HPV) which can cause cervical intraepithelial neoplasia. Greater than 90% of cervical cancers develop in the transformation zone (TZ), a small region of metaplastic squamous epithelium at the squamocolumnar junction between endocervix and ectocervix. However, it is unclear why this region is highly susceptible to malignant progression. We hypothesized that cells from TZ were more susceptible to dysplastic differentiation, a precursor to cervical cancer. We used three-dimensional organotypic culture to compare differentiation of HPV16-immortalized epithelial cell lines derived from ectocervix, TZ, and endocervix. We show that immortal cells from TZ or endocervix form epithelia that are more dysplastic than immortal cells from ectocervix. A higher percentage of immortal cells from TZ and endocervix express the proliferation marker Ki-67 and are positive for phospho-Akt. Immortal cells from TZ and endocervix invade collagen rafts and express increased levels of matrix metalloproteinase-1. Inhibition of MMP-1 or Akt activity blocks invasion. We conclude that HPV16-immortalized cells cultured from TZ or endocervix are more susceptible to dysplastic differentiation, and this might enhance their susceptibility to cervical cancer.
Neutralizing antibodies to Severe Fever with Thrombocytopenia Syndrome Virus in general population, Shandong Province, China
Authors: Li Dexin , Shao Lijun , Bi Yu , Niu Guoyu
Published: October 2018

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by SFTS virus (SFTSV) in East Asia. The research on seroprevalence of SFTSV in healthy people and risk factors had been detailed. However, the levels of neutralizing antibodies against SFTSV in general population were currently unclear. In the present study, we tested 1375 healthy persons from Penglai County, eastern China, for SFTSV neutralizing antibodies; 0.58% (8/1,375) was positive and the positive rates were not significantly different among people at different age groups, occupations and genders. Besides, a follow-up study was conducted and the titer of neutralizing antibodies decreased over time in all eight people but one, and the neutralizing antibodies of five lasted for the entire study period of seven years. Our results suggesting that subclinical infection or a relatively mild form of SFTS illness is occurring in this population, but a small percentage of sera have neutralizing capacity to SFTSV. Hence, most people are just susceptible to SFTSV infection.
An autoimmune disease risk SNP, rs2281808, in SIRPG is associated with reduced expression of SIRPγ and heightened effector state in human CD8 T-cells
Authors: Sinha Sushmita , Borcherding Nicholas , Renavikar Pranav S. , Crawford Michael P. , Tsalikian Eva , Tansey Michael , Shivapour Ezzatollah T. , Bittner Frank , Kamholz John , Olalde Heena , Gibson Emilee , Karandikar Nitin J.
Published: October 2018

Multiple GWAS studies have shown that the SNP rs2281808 TT variant, present within the SIRPG gene, is associated with autoimmune diseases, such as type 1 diabetes. However, the role of SIRPγ in human T-cells is not known, neither is the functional significance of TT variant. Here we investigated SIRPG genotypes and their effects on the fate and function of human T-cells. We found that the presence of T variant resulted in reduction of SIRPγ expression on T-cells. Functionally, SIRPγlow CD8 T-cells in CT and TT individuals existed in a heightened effector state with lower activation threshold and had greater expression of genes and molecules associated with migratory and cytotoxic potential. Further, SIRPγlow CD8 T-cells were deficient in transcription factors associated with long-term functional memory formation. Our study reveals biological consequences of the SNP rs2281808 and provides novel insights into the potential mechanisms by which SIRPγ might regulate human immune responses.
First-principles insights on the electronic and optical properties of ZnO@CNT core@shell nanostructure
Authors: Shen Yang , Yang Xiaodong , Bian Yue , Nie Kuiying , Liu Songmin , Tang Kun , Zhang Rong , Zheng Youdou , Gu Shulin
Published: October 2018

In recent years, various kinds of ZnO-based core@shell nanomaterials have been paid much attention due to their widespread applications in the fields of physics, chemistry and energy conversion. In this work, the electronic and optical properties of a new type of ZnO-based one-dimensional core@shell nanostructure, which is composed of inner ZnO nanowire and outer carbon nanotube (CNT), is calculated based on the first-principles density functional theory (DFT). Calculation results suggest that the ZnO nanowire encapsulated in (9, 9)-CNT is the most stable structure from the view of formation energy. The interaction between the inner ZnO nanowire and the outer (9, 9) CNT belongs to a weak van der Waals type. The complex structure is found to possess metallicity for the outer (9, 9) CNT and maintain the wide band gap nature for the inner ZnO nanowire. Under the different external strains, the charge redistribution between inner ZnO nanowire and outer CNT caused by electron tunneling leads to the shift of Dirac point and the band narrowing of inner ZnO nanowire. The inner ZnO nanowire only has light absorption in the UV region, which is consistent with its optical property originating from its wide bandgap nature.
Liquid-phase catalysis by single-size palladium nanoclusters supported on strontium titanate: size-specific catalysts for Suzuki–Miyaura coupling
Authors: Tsunoyama Hironori , Ito Haruchika , Komori Masafumi , Kobayashi Ryota , Shibuta Masahiro , Eguchi Toyoaki , Nakajima Atsushi
Published: October 2018

Size-specific catalysis by single-size palladium nanoclusters.
Variable coordination of carbazolyl-bis(tetrazole) ligands in lanthanide chemistry
Authors: Gajecki Leah , Berg David J. , Hoenisch Josh , Oliver Allen G.
Published: October 2018

Lanthanide complexes of 1,8-bis(2′-isopropyltetrazo-5′-yl)-3,6-di-tert-butylcarbazolide adopt geometries that include planar, buckled and tetrazolyl-bridged tridentate, as well as bidentate, bonding modes.
Suppressing glucose metabolism with epigallocatechin-3-gallate (EGCG) reduces breast cancer cell growth in preclinical models
Authors: Wei Ran , Mao Limin , Xu Ping , Zheng Xinghai , Hackman Robert M. , Mackenzie Gerardo G. , Wang Yuefei
Published: October 2018

EGCG reduces breast cancer growth through the inhibition of key enzymes that participate in the glycolytic pathway and the suppression of glucose metabolism.
Influence of baseline subtraction on laser-induced breakdown spectroscopic data
Authors: Képeš Erik , Pořízka Pavel , Klus Jakub , Modlitbová Pavlína , Kaiser Jozef
Published: October 2018

Automatic baseline subtraction significantly improves the quality of high-background spectra but might harm low-background spectra.
Synthesis and characterization of silver nanoparticle-loaded amorphous calcium phosphate microspheres for dental applications
Authors: Keskar Mayuresh , Sabatini Camila , Cheng Chong , Swihart Mark T.
Published: October 2018

Synthesis of composite nanostructures of amorphous calcium phosphate loaded with silver nanoparticles has been achieved using a spray pyrolysis method. Upon incorporation into a commercial dental adhesive resin, these nanostructures provide sustained release of silver, calcium, and phosphate ions.
Assembly of graphene nanoflake–quantum dot hybrids in aqueous solution and their performance in light-harvesting applications
Authors: Attanzio Antonio , Rosillo-Lopez Martin , Zampetti Andrea , Ierides Ioannis , Cacialli Franco , Salzmann Christoph G. , Palma Matteo
Published: October 2018

Graphene nanoflake and CdSe/ZnS quantum dot nanohybrids were assembled in aqueous solution and investigated as potential light harvesting assemblies.
Enhanced absorption of TiO2nanotubes by N-doping and CdS quantum dots sensitization: insight into the structure
Authors: Bjelajac Andjelika , Petrović Rada , Djokic Veljko , Matolin Vladimir , Vondraček Martin , Dembele Kassioge , Moldovan Simona , Ersen Ovidiu , Socol Gabriel , Mihailescu Ion N. , Janaćković Djordje
Published: October 2018

A simple two-step procedure to shift the absorption of TiO2nanotubes to the visible range.
The streptazolin- and obscurolide-type metabolites from soil-derivedStreptomyces albonigerYIM20533 and the mechanism of influence of γ-butyrolactone on the growth ofStreptomycesby their non-enzymatic reaction biosynthesis
Authors: Luo Na , Yang Ya-Bin , Yang Xue-Qiong , Miao Cui-Ping , Li Yi-Qing , Xu Li-Hua , Ding Zhong-Tao , Zhao Li-Xing
Published: October 2018

Eleven new compounds with streptazolin- and obscurolide-type skeletons were isolated from soil-derivedStreptomyces albonigerobtained from Tibet, China.
miR-183-96-182 clusters alleviated ox-LDL-induced vascular endothelial cell apoptosis in vitro by targeting FOXO1
Authors: Liu Zhi-Qin , Du Jing-Jing , Ren Jing-Jing , Zhang Zhi-Yong , Guo Xiao-Bo , Yan Yu-E. , Jia Xiao-Tao , Gu Nai-Bing , Di Zheng-Li , Li San-Zhong
Published: October 2018

The present research represents the first insight into miRNA regulating FOXO1 expression in atherosclerotic endothelial cells.
Retracted Article: MiR-182-5p and miR-96-5p increased hepatocellular carcinoma cell mobility, proliferation and cisplatin resistance partially by targeting RND3
Authors: Yang Shiming , Chen Zhi , Fan Daguang , Zhang Rui , Zhang Yuhong , Wu Shusheng
Published: October 2018

We investigated whether miR-182-5p or miR-96-5p could increase hepatocellular carcinoma (HCC) development by targeting Rho Family GTPase 3 (RND3) gene expression.
Morphology and electrical characteristics of p-type ZnO microwires with zigzag rough surfaces induced by Sb doping
Authors: Shi Linlin , Du Luchao , Xu Yingtian , Jin Liang , Zhang He , Li Yan , Ma Xiaohui , Zou Yonggang , Zhao Dongxu
Published: October 2018

Sb-doped microwires which have a zigzag rough surface demonstrate p-type conduction and enhanced rectifying behavior with increasing Sb doping concentration.
Preparation of polycarbonate diols (PCDLs) from dimethyl carbonate (DMC) and diols catalyzed by KNO3/γ-Al2O3
Authors: Song Menglu , Yang Xiangui , Wang Gongying
Published: October 2018

γ-Al2O3 loaded with potassium nitrate (KNO3/Al2O3) catalysts were prepared, characterized and employed as a type of heterogenous solid base catalyst in the synthesis of polycarbonate (1,4-butane carbonate)-diol (PBC–OH) via the transesterification of dimethyl carbonate (DMC) and 1,4-butanediol (BD).
Morphology engineering of nickel molybdate hydrate nanoarray for electrocatalytic overall water splitting: from nanorod to nanosheet
Authors: Wang Jianghao , Li Liping , Meng Lingshen , Wang Liping , Liu Yifeng , Li Wenwen , Sun Wengang , Li Guangshe
Published: October 2018

We realize the modulation of nanoarray morphology from nanorod to nanosheet and improve the catalytic activity for water splitting by simply changing the hydrothermal temperature.
Quantitative relationship between cavitation and shear rheology
Authors: Bentz Kyle C. , Sultan Naomi , Savin Daniel A.
Published: October 2018

A quantitative framework is developed for comparing cavitation moduli with traditional oscillatory shear rheology for three series of model gels.
Oil-induced formation of branched wormlike micelles in an alcohol propoxysulfate extended surfactant system
Authors: Choi Francis , Acosta Edgar J.
Published: October 2018

The hydrophilic–lipophilic-difference framework predicts the oil and salinity required to induce wormlike micelle formation from surfactant–water systems.
Collagen degradation in tuberculosis pathogenesis: the biochemical consequences of hosting an undesired guest
Authors: Squeglia Flavia , Ruggiero Alessia , Berisio Rita
Published: October 2018

The scenario of chemical reactions prompted by the infection by Mycobacterium tuberculosis is huge. The infection generates a localized inflammatory response, with the recruitment of neutrophils, monocytes, and T-lymphocytes. Consequences of this immune reaction can be the eradication or containment of the infection, but these events can be deleterious to the host inasmuch as lung tissue can be destroyed. Indeed, a hallmark of tuberculosis (TB) is the formation of lung cavities, which increase disease development and transmission, as they are sites of high mycobacterial burden. Pulmonary cavitation is associated with antibiotic failure and the emergence of antibiotic resistance. For cavities to form, M. tuberculosis induces the overexpression of host proteases, like matrix metalloproteinases and cathepsin, which are secreted from monocyte-derived cells, neutrophils, and stromal cells. These proteases destroy the lung parenchyma, in particular the collagen constituent of the extracellular matrix (ECM). Namely, in an attempt to destroy infected cells, the immune reactions prompted by mycobacterial infections induce the destruction of vital regions of the lung, in a process that can become fatal. Here, we review structure and function of the main molecular actors of ECM degradation due to M. tuberculosis infection and the proposed mechanisms of tissue destruction, mainly attacking fibrillar collagen. Importantly, enzymes responsible for collagen destruction are emerging as key targets for adjunctive therapies to limit immunopathology in TB.
HER2 decreases drug sensitivity of ovarian cancer cells via inducing stem cell-like property in an NFκB-dependent way
Authors: Wang Wenxiang , Gao Yuxia , Hai Jing , Yang Jing , Duan Shufeng
Published: October 2018

Increasing evidence shows that cancer stem cells are responsible for drug resistance and relapse of tumors. In breast cancer, human epidermal growth factor receptor 2 (HER2) induces Herceptin resistance by inducing cancer stem cells. In the present study, we explored the effect of HER2 on cancer stem cells induction and drug sensitivity of ovarian cancer cell lines. First, we found that HER2 overexpression (HER2 OE) induced, while HER2 knockdown (HER2 KD) decreased CD44+/CD24− population. Consistently, HER2 expression was closely correlated with the sphere formation efficiency (SFE) of ovarian cancer cells. Second, we found that NFκB inhibition by specific inhibitor JSH23 or siRNA targetting subunit p65 dramatically impaired the induction of ovarian cancer stem cells by HER2, indicating that NFκB mediated HER2-induced ovarian cancer stem cells. Third, we found that HER2 KD significantly attenuated the tumorigenicity of ovarian cancer cells. Further, we found that HER2 inhibition increased drastically the sensitivity of ovarian cancer cells to doxorubicin (DOX) or paclitaxel (PTX). Finally, we examined the correlation between HER2 status and stem cell-related genes expression in human ovarian tumor tissues, and found that expressions of OCT4, COX2, and Nanog were higher in HER2 positive tumors than in HER2 negative tumors. Consistently, the 5-year tumor-free survival rate of HER2 positive patients was dramatically lower than HER2 negative patients. Taken together, our data indicate that HER2 decreases drug sensitivity of ovarian cancer cells via inducing stem cell-like property.
Enzymatic complexes across scales
Authors: Kastritis Panagiotis L. , Gavin Anne-Claude
Published: October 2018

An unprecedented opportunity to integrate ~100 years of meticulous in vitro biomolecular research is currently provided in the light of recent advances in methods to visualize closer-to-native architectures of biomolecular machines, and metabolic enzymes in particular. Traditional views of enzymes, namely biomolecular machines, only partially explain their role, organization and kinetics in the cellular milieu. Enzymes self- or hetero-associate, form fibers, may bind to membranes or cytoskeletal elements, have regulatory roles, associate into higher order assemblies (metabolons) or even actively participate in phase-separated membraneless organelles, and all the above in a transient, temporal and spatial manner in response to environmental changes or structural/functional changes of their assemblies. Here, we focus on traditional and emerging concepts in cellular biochemistry and discuss new opportunities in bridging structural, molecular and cellular analyses for metabolic pathways, accumulated over the years, highlighting functional aspects of enzymatic complexes discussed across different levels of spatial resolution.
Reverse engineering gene regulatory networks by modular response analysis – a benchmark
Authors: Klinger Bertram , Blüthgen Nils
Published: October 2018

Gene regulatory networks control the cellular phenotype by changing the RNA and protein composition. Despite its importance, the gene regulatory network in higher organisms is only partly mapped out. Here, we investigate the potential of reverse engineering methods to unravel the structure of these networks. Particularly, we focus on modular response analysis (MRA), a method that can disentangle networks from perturbation data. We benchmark a version of MRA that was previously successfully applied to reconstruct a signalling-driven genetic network, termed MLMSMRA, to test cases mimicking various aspects of gene regulatory networks. We then investigate the performance in comparison with other MRA realisations and related methods. The benchmark shows that MRA has the potential to predict functional interactions, but also shows that successful application of MRA is restricted to small sparse networks and to data with a low signal-to-noise ratio.
Microtubule nucleation by γ-tubulin complexes and beyond
Authors: Tovey Corinne A. , Conduit Paul T.
Published: October 2018

In this short review, we give an overview of microtubule nucleation within cells. It is nearly 30 years since the discovery of γ-tubulin, a member of the tubulin superfamily essential for proper microtubule nucleation in all eukaryotes. γ-tubulin associates with other proteins to form multiprotein γ-tubulin ring complexes (γ-TuRCs) that template and catalyse the otherwise kinetically unfavourable assembly of microtubule filaments. These filaments can be dynamic or stable and they perform diverse functions, such as chromosome separation during mitosis and intracellular transport in neurons. The field has come a long way in understanding γ-TuRC biology but several important and unanswered questions remain, and we are still far from understanding the regulation of microtubule nucleation in a multicellular context. Here, we review the current literature on γ-TuRC assembly, recruitment, and activation and discuss the potential importance of γ-TuRC heterogeneity, the role of non-γ-TuRC proteins in microtubule nucleation, and whether γ-TuRCs could serve as good drug targets for cancer therapy.
Microtubule structure by cryo-EM: snapshots of dynamic instability
Authors: Manka Szymon W. , Moores Carolyn A.
Published: October 2018

The development of cryo-electron microscopy (cryo-EM) allowed microtubules to be captured in their solution-like state, enabling decades of insight into their dynamic mechanisms and interactions with binding partners. Cryo-EM micrographs provide 2D visualization of microtubules, and these 2D images can also be used to reconstruct the 3D structure of the polymer and any associated binding partners. In this way, the binding sites for numerous components of the microtubule cytoskeleton—including motor domains from many kinesin motors, and the microtubule-binding domains of dynein motors and an expanding collection of microtubule associated proteins—have been determined. The effects of various microtubule-binding drugs have also been studied. High-resolution cryo-EM structures have also been used to probe the molecular basis of microtubule dynamic instability, driven by the GTPase activity of β-tubulin. These studies have shown the conformational changes in lattice-confined tubulin dimers in response to steps in the tubulin GTPase cycle, most notably lattice compaction at the longitudinal inter-dimer interface. Although work is ongoing to define a complete structural model of dynamic instability, attention has focused on the role of gradual destabilization of lateral contacts between tubulin protofilaments, particularly at the microtubule seam. Furthermore, lower resolution cryo-electron tomography 3D structures are shedding light on the heterogeneity of microtubule ends and how their 3D organization contributes to dynamic instability. The snapshots of these polymers captured using cryo-EM will continue to provide critical insights into their dynamics, interactions with cellular components, and the way microtubules contribute to cellular functions in diverse physiological contexts.
Improvement of operation of power transformer protection system during sympathetic inrush current phenomena using fault current limiter
Authors: Hossein Sadeghi Mohammad , Damchi Yaser , Shirani Hosseinali
Published: October 2018

Power transformer protection has a high sensitivity due to its important role in power systems. Various factors such as inrush and sympathetic inrush currents may result in the inappropriate performance of protective relays and cause problems such as power outage or blocking of sensitive loads. Until now, several studies have been performed on the detection and reduction of inrush current, however, the effect of sympathetic inrush current on transformer protection has not been addressed. In this study, the operation of the protection system during the sympathetic inrush current is comprehensively analysed. Furthermore, the use of a fault current limiter is proposed to reduce the undesirable effects of the phenomena. The effects of the limiter on the saturation of power and current transformers are investigated. A real transmission station is simulated using DIgSILENT Power Factory Software to perform these studies by considering the resistive and impedance fault current limiter.‏ Results show that protective relays do not have an improper operation during the phenomena with limiters. Moreover, with the resistive fault current limiter, sympathetic inrush and inrush currents are decreased by 5 and 15% more than the impedance fault current limiter, respectively. Saturation of power and current transformers is significantly reduced with limiters, especially with a resistive fault current limiter.
Coordinative real‐time sub‐transmission volt–var control for reactive power regulation between transmission and distribution systems
Authors: Ke Xinda , Samaan Nader , Holzer Jesse , Huang Renke , Vyakaranam Bharat , Vallem Mallikarjuna , Elizondo Marcelo , Lu Ning , Zhu Xiangqi , Werts Brant , Nguyen Quan , Huang Alex , Makarov Yuri V.
Published: October 2018

This study introduces a new approach for coordinating volt–var control (VVC) between sub‐transmission and distribution systems through optimal reactive power dispatch of distributed energy resources (DERs) that are aggregated as virtual power plants (VPPs). At the sub‐transmission level, shunt devices and the reactive power provided by the VPPs are coordinated and optimised using a VVC algorithm with weighted sum of multiple objects that include minimising voltage deviations from desirable levels at load buses, minimising loses, minimising solar curtailment, minimising demand response usage and minimising mechanical switching of shunt elements. The algorithm runs every 5 min and is solved using the AC optimal power flow technique. At the distribution level, each VPP runs a distribution VVC algorithm to dispatch reactive power from DERs. The goal of the VPP reactive power control is to meet sub‐transmission service requirements while satisfying all the constraints at the distribution side. Each VPP updates its reactive power capability every 5 min to allow the sub‐transmission controller to formulate the optimisation problem for the next dispatch interval. The proposed tool is simulated on a Duke Energy Carolina system to demonstrate the capability of providing voltage support by dispatching reactive power of DERs as a VPP.
Robust hierarchical damping controller for uncertain wide‐area power systems
Authors: Bijami Ehsan , Farsangi Malihe M.
Published: October 2018

This study develops a new robust hierarchical predictive sliding mode controller to damp the wide‐area electromechanical oscillations in an uncertain wide‐area power system. The coefficient matrices of wide‐area systems are often sparse matrices which cause the inverse calculation of them very complex or impossible. In the suggested approach, first the entire system is divided into several small subsystems with non‐sparse matrices and lower order; then a new predictive sliding mode controller with robust reaching law is designed to provide the optimal performance and robustness to uncertainties and external disturbances. Also, the gradient of interaction errors is employed for coordination of overall wide‐area system. The capability and efficiency of the developed control framework is verified through numerical simulations on an uncertain power grid with interconnected multi‐areas, for various cases of perturbations and parameters’ uncertainties. Simulation studies illustrate the effectiveness of the suggested method to improve the wide‐area power grid damping in terms of acceptable robustness to external disturbances and system's parameter variations, in comparison with two other methods which are adopted from the literature.
Radio-loud AGN in the first LoTSS data release
Authors: Hardcastle M. J. , Williams W. L. , Best P. N. , Croston J. H. , Duncan K. J. , Röttgering H. J. A. , Sabater J. , Shimwell T. W. , Tasse C. , Callingham J. R. , Cochrane R. K. , de Gasperin F. , Gürkan G. , Jarvis M. J. , Mahatma V. , Miley G. K. , Mingo B. , Mooney S. , Morabito L. K. , O’Sullivan S. P. , Prandoni I. , Shulevski A. , Smith D. J. B.
Published: October 2018

We constructed a sample of 23 344 radio-loud active galactic nuclei (RLAGN) from the catalogue derived from the LOFAR Two-Metre Sky Survey (LoTSS) survey of the HETDEX Spring field. Although separating AGN from star-forming galaxies remains challenging, the combination of spectroscopic and photometric techniques we used gives us one of the largest available samples of candidate RLAGN. We used the sample, combined with recently developed analytical models, to investigate the lifetime distribution of RLAGN. We show that large or giant powerful RLAGN are probably the old tail of the general RLAGN population, but that the low-luminosity RLAGN candidates in our sample, many of which have sizes < 100 kpc, either require a very different lifetime distribution or have different jet physics from the more powerful objects. We then used analytical models to develop a method of estimating jet kinetic powers for our candidate objects and constructed a jet kinetic luminosity function based on these estimates. These values can be compared to observational quantities, such as the integrated radiative luminosity of groups and clusters, and to the predictions from models of RLAGN feedback in galaxy formation and evolution. In particular, we show that RLAGN in the local Universe are able to supply all the energy required per comoving unit volume to counterbalance X-ray radiative losses from groups and clusters and thus prevent the hot gas from cooling. Our computation of the kinetic luminosity density of local RLAGN is in good agreement with other recent observational estimates and with models of galaxy formation.
A note on inverse problem for strongly damped wave equation with Gaussian white noise
Authors: Khanh Chu Duc , Hoang Luc Nguyen , Phan Van , Huy Tuan Nguyen
Published: October 2018

In this paper, we study for the first time the inverse initial problem for the one-dimensional strongly damped wave with Gaussian white noise data. Under some a priori assumptions on the true solution, we propose the Fourier truncation method for stabilizing the ill-posed problem. Error estimates are given in both the L2– and Hp–norms.
Regularity for the second order Riesz transforms associated with Schrödinger operators on weighted BMO type spaces
Authors: Nguyen Ngoc Trong , Nguyen Anh Dao , Truong L. X.
Published: October 2018

Let L = −Δ + V be a Schrödinger operator on ℝn, where V is a nonnegative potential satisfying the suitable reverse Hölder’s inequality. In this paper, we study the boundedness of the second order Riesz transforms such as L−1∇2on the spaces of BMO type for weighted case. We generalized the known results to the weighted case.
Identify the correlation between the teaching perspectives and student evaluation: A case study of a sample university in Ho Chi Minh city
Authors: Nguyen Huy , Briš Radim
Published: October 2018

Education is a critical issue in any cultural background. In fact, the quality of teaching shall be considered and linked with student evaluation because there seems to have a strong correlation between them. This study aims to understand the different perspectives on teaching by academic staffs of a university X in Ho Chi Minh City and also is to determine whether there are one or two dominant teaching perspective preferences. In addition, the students’ comments were also collected and investigated to identify whether or not there are relationships between these dominant teaching perspectives and student end-of-course evaluations. Finally, the researcher proposed a new form of evaluation to help measure better students’ expectations.
Application of CLP for technical objects construction with an exemplary bucket elevation
Authors: Bartnik Grzegorz , Marciniak Andrzej , Gołacki Krzysztof
Published: October 2018

The paper presents the application of the Constraint Logic Programming (CLP) language for designing technical objects. The method was described and illustrated based with the help of on the bucket elevator design. The hierarchical structure of the object, way of system configuration and exemplary sets of fitted components are presented.
Adaptive concept of state estimation with incomplete state vector measurement
Authors: Kwater Tadeusz , Krutys Paweł , Pękala Robert , Kwiatkowski Bogdan
Published: October 2018

The paper presents the design and simulation experiments of the adaptive approach in the estimation of the object state realized by filter whose gain is calculated on-line. The adopted concept of determining the gain uses a defined for this purpose signal called an error and on the basis of its waveform features introduces an incremental correction of the amplification factor of the estimation filter. The obtained results of state estimation are characterized by stability and strong correctness even for cases of non-stationary disturbances
The monitoring system based on lookup algorithm for objects described by ordinary differential equations
Authors: Hawro Przemysław , Kwater Tadeusz , Strzęciwilk Dariusz
Published: October 2018

The article presents a new approach to monitoring systems of a certain class using the lookup algorithm. The main task is to generate object signals based on measured but only some selected signals. This idea is based on the Kalman filter approach, but the calculation method of the gain coefficients is different. Its values are determined in a similar way as weights in neural networks during learning (incremental method). The proposed lookup algorithm uses expert knowledge a priori for determining gain corrections, and its functioning is presented for the case of two monitoring error zones. The presented results clearly indicate the advantage of the lookup algorithm over the Kalman filter. Two RMSE and MPE indicators were used for the quality of monitoring.
Mapping Accuracy of Trajectories of Manipulator Motion
Authors: Boryga Marek , Kołodziej Paweł , Graboś Andrzej , Gołacki Krzysztof
Published: October 2018

The paper presents the algorithm for trajectory planning and the analysis of motion accuracy of an anthropomorphic manipulator whose the end-effector moves over the rectilinear-arc path. The path consists of two rectilinear segments of intersecting directions coupled with the arc of a fixed radius. On these rectilinear segments, the end-effector acceleration is described by a polynomial of 7th-degree. The motion over the arc proceeds at a constant velocity. The dynamic analysis was carried out on the basis of Lagrange’s equations of the second order. Manipulator flexibility and damping were considered according to the Kelvin-Voigt model introducing spring-damping components into the drive system. The simulation test results were presented in the form of spatial courses of the pre-assigned and realized trajectories as well as time courses of trajectory end-effector mapping errors for three paths with different radii of the arc.
The use of the power law for designing wireless networks
Authors: Paszkiewicz Andrzej
Published: October 2018

The paper concerns the use of the scale-free networks theory and the power law in designing wireless networks. An approach based on generating random networks as well as on the classic Barabási-Albert algorithm were presented. The paper presents a new approach taking the limited resources for wireless networks into account, such as available bandwidth. In addition, thanks to the introduction of opportunities for dynamic node removal it was possible to realign processes occurring in wireless networks. After introduction of these modifications, the obtained results were analyzed in terms of a power law and the degree distribution of each node.
The possibility of using LACP protocol in anomaly detection systems
Authors: Bolanowski Marek , Cisło Piotr
Published: October 2018

This article presents the use of the Link Aggregation Control Protocol (LACP) for detection of anomalies in network traffic. The idea itself is based on checking the representativeness of a single LACP link for the whole traffic transmitted by the aggregation. This approach allows to reduce the requirements for the performance of threat detection systems, and thus reduce their implementation costs and the gives a possibility of using probes (IDS or IPS) directly in the core of the network. The authors also examine the influence of hashing algorithms used for the particular LACP link on the possibility of using of developed method and on the level of intrusion detection.
Multifractal Analysis Of Selected Multicast Routing Protocols In IP Networks
Authors: Dymora Paweł , Mazurek Mirosław , Strzałka Dominik
Published: October 2018

The article presents results of studies using simulations on computer network devices, designed to examine the effectiveness of routing protocols with the video streaming and generated traffic for Jperf applications. In order to demonstrate the effectiveness of the selected protocols several simulation scenarios were made using different sized UDP packets. The traffic was analyzed in terms of statistical self-similarity. Multifractal analysis has also been made, using two kinds of spectrums. The study determined the relationship between them. These tasks were designed to determine the multifractal and long-term relationship for a given process.
Open data – an introduction to the issue
Authors: Dymora Paweł , Mazurek Mirosław , Kowal Bartosz
Published: October 2018

Rapidly developing of internet technologies and digitalization of government generate more and more data. Databases from various public institutions and private sectors, e.g. in the fields of economics, transport, environment and public safety are publishing in the global Internet network, so that any user can browse them without additional charges. Most of this data is published on the open data portals. Open data - that is, “open”, public data can allow the processing and analysis of information contained in them completely free of charge. This article is an introduction to a fairly new area of issues such as “open data” or “open government”, presents the main mechanisms of accessing to data in public open data portals and also propose a conceptual open data/government model.
Analysis of the influence of selected non-linear devices on the waveform of supply voltage
Authors: Bartman Jacek , Sobczyński Dariusz
Published: October 2018

The paper presents research on the influence of selected non-linear devices on the shape of supply voltage. It has been assessed how current distortion, expressed by THDI, and rms current ‖i‖ influence voltage distortion, represented by THDU. For this purpose, an induction generator with a power comparable to that of the loads was used to power the loads. The devices were selected in such a way as to increase current distortion with the decrease of rms current. The measurements were made with a class A energy quality analyzer.
One day ahead forecasting of energy generating in photovoltaic systems
Authors: Drałus Grzegorz , Dec Grzegorz , Mazur Damian
Published: October 2018

The article presents selected methods for forecasting energy generated by a solar system. Short-term forecasts are necessary in planning the work of renewable energy sources and their share in the energy market. Forecasting from the one-day horizon is one of the short-term forecasts. Rear-round prognostic models have been designed using various forecasting methods such as regression, neural networks or time series. On the basis of one day ahead forecasts the accuracy of designed models was assessed. The influence of selected weather factors on forecasts accuracy is also presented, only for models implemented by MLP neural networks. As well as the results of research on the impact of the model structure (as MLP neural network) on the accuracy of forecasts are presented.
Toponymy of Irkutsk Region as a Part of Linguocultural Space of the Region
Authors: Chupanovskaya Mariya , Maklakova Tatyana , Nikitina Albina
Published: October 2018

The article deals with the toponymy of Irkutsk region as a significant component of regional linguocultural space. A brief history of the territory development is offered, as well as information on indigenous peoples due to the fact that the toponyms of Eastern Siberia date back to different language sources. The paper examines the ethno-linguistic layers of toponyms, analyses the results of cross-language contacts reflected in geographical names, and draws conclusions on cultural syncretism on the region’s territory. Authors analyze captured in Russian and foreign toponymy peculiarities of the world perception by local old residents, their attitude to a man, family, family line, flora and fauna. Value orientations of the locals are identified. On the material of official and unofficial toponyms the following phenomena of regional ethnic culture are described: ethnic unity, life, traditions, religion, rituals, and symbols.
Phenomenon of a Teacher Within a Historical Context
Authors: Ilaltdinova Elena , Lebedeva Irina , Frolova Svetlana , Arifulina Ramilya , Belyaeva Tatyana
Published: October 2018

The study concerns the phenomenon of a “professional teacher”, its social status, personal qualities and competences within the historical context. The authors apply the integration of philosophical, psychological, historical-pedagogical and pedagogical knowledge as such to understand the modern model of a teacher. The historical context as a complex of social conditions of pedagogical insights, concepts and assumptions of an ideal teacher and its professional training formed methodological fundamentals of the study dealing with the image of a teacher of the past, present and future. To define the mission of a teacher within the society and its professional characteristics the study analyzes beliefs, activities and works of educators, scientists, classic teachers and modern representatives of pedagogical science and educational practice. Defining the phenomenon of a “teacher”, the authors consider it through the unique nature of professional activity, personal qualities, compliance to public expectations and demands.
Features of Students’ Attributional Style
Authors: Ignatova Valentina , Baranovskaya Larisa , Kudryavtsev Mikhail , Galimova Alena , Galimov Gennady , Dagbaev Bator , Doroshenko Sergey , Kamoza Tatyana , Harutyunyan Tigran , Kondratyuk Tatyana , Plotnikova Irina
Published: October 2018

Attributional style or explanatory style is a cognitive personal feature reflecting a standard specific way of explaining the reasons of events in which people are involved. This concept is key in M. Seligman’s theory of learned helplessness and depression. M. Seligman and his followers experimentally proved that the person becomes helpless in case he is convinced that nothing depends on his active actions, that evil events happen accidentally, and it is impossible to change them. The paper describes features of attributional style of junior students and provides recommendations on overcoming its negative consequences.
Grammatical and Semantic Word-Formation of Toponymic Derivatives (on the Material of the Toponym “CИБИPЬ”)
Authors: Litovkina Anna M.
Published: October 2018

The paper presents morphemic-derivational structure of toponymic derivatives (toponymy-derived formations) of proper name “Cибирь”. In revealed derived words authors identify morphemes, specify the methods of their production, provide statistics on word-formation activity of morphemes in the process of secondary nomination of toponymy-derived appellatives. Based on regional material of dialectal dictionaries they define the peculiarities of toponym’s word-formation family of words, as well as its paradigmatic relations with derived categories. Horonym “Cибирь” is considered in the context of perception by regional linguistic persona in the national toponymic space. Examples of semantic toponymy-derived word-formation are given. Thereby, in Russian language world picture it is possible to identify a set of regionally marked background knowledge, perceptions of values as well as historical and cultural characteristics of the analyzed toponym.
Creative approach to development of competence “writing” in foreign language classes
Authors: Aleshchanova Irena V. , Frolova Natalia A. , Zheltukhina Marina R.
Published: October 2018

This study examines the question of development of an important component of the foreign language communicative competence - the skill of writing as a structural element of the technical university students’ professional competence. The methods and ways of the stated aim achievement are analyzed from the perspective of the competence and personality-oriented approaches. Professional communication is presented as a multicomponent phenomenon, requiring detailed study. Foreign and domestic research in the field of foreign language teaching formed the theoretical basis for studying the methodical and didactic aspects of writing activities. The authors define students’ acquisition of writing skills in the process of education as the development of elementary communicative competence. Tasks for the writing skills development are described as a productive tool for organizing educational activities. The authors emphasize the special role of creative tasks and how they can contribute to achieving the set goals in teaching. Practical recommendations on the development of writing skills and this process monitoring are given.
Analysis of Activity Efficiency of Private Pension Fund at Regional Level
Authors: Bitkina Irina K.
Published: October 2018

The presented study is devoted to an analysis of activity of private pension funds at the regional level. Results connected with generalization of the available theoretical developments in selected thesis of the study are shown in the article. There is also the author’s approach to the evidence of efficiency of private pension funds estimation and practical conclusions on estimations of efficiency of activity of regional private pension funds in south federal neighborhood.
Metaphorical Modeling of Negotiations on ‘Jamaica Coalition’ in Mass Media of Germany
Authors: Bykova Liudmila , Tadzhibova Aksana
Published: October 2018

The article deals with the metaphoric modeling of media discourse by the example of the negotiations on ‘Jamaica coalition’ in mass media of Germany. Such spheres-sources of metaphorical expansion as Disease, Sport, Nature and Food/Kitchen and Theatre and their activity are analysed in the article. It is shown that the metaphor helps publicists to solve any communicative tasks they need. The metaphor possesses a pragmatical function in media discourse, it can attract and provide simplicity of perception of information and, therefore, form a positive or negative attitude towards it. According to the analysis the process of coalition creation is presented by means of different types of metaphors as a set of rehearsed actions in advance, spectacular performances of various emotional character, sometimes with unpredictable, obscure results.
Secondary Musical Personality: Structure, Psychological Mechanism of Development
Authors: Cheremisova Irina V.
Published: October 2018

Today’s socio-cultural situation requires new approaches to education. The aesthetic and semiotic approach promotes the humanization of the modern education and the development of the student’s holistic creative personality by means of classical musical art. From the standpoint of the aesthetic and semiotic approach, music is understood as a complex psychosemantic text. Due to the theoretical analysis of the studies of a secondary language personality and the studies of music and speech psychological kinship, the notion of a secondary musical personality as a kind of a secondary linguistic personality has been elaborated. The author has developed the structure and disclosed a psychological mechanism for developing a secondary musical personality. This psychological mechanism was tested as part of the longitudinal study. The structure of a secondary musical personality is presented as an aggregate of musical and cognitive, motivational, emotional, communicative, pragmatist, and spiritual and moral (axiological) components. The psychological mechanism for developing a secondary musical personality is a system of interrelated conditions and factors. These conditions and factors include: the complexity, polysemy, and semantic versatility of a musical text; musical valence; the psychological mechanism of figurative verbalization, etc. Musical enculturation serves as a universal developing mechanism.