bluuebunny/crossref_metadata_2025 huggingface dataset:
Water budget study for groundwater recharge in Indus River Basin, Punjab (Pakistan)
Authors: Zakir-Hassan Ghulam , Akhtar Saleem , Shabir Ghulam , Hassan Faiz Raza , Ashraf Hadeed , Sultan Muhammad
Published: July 2023

Assessing groundwater recharge is crucial for managing and governing water resources in any region. Indus River Basin (IRB) is an area that relies heavily on canal and groundwater irrigation. The replenishment of groundwater is largely dependent on surface water supplies. The purpose of this research is to determine the amount of groundwater recharge from various sources in Rachna Doab. The study employed the water budget method to calculate seasonal groundwater recharge during the Rabi (October–March) and Kharif (April–September) (Summer) periods from 2005 to 2011. The main components of the recharge were rainfall, water conveyed through channels, and irrigation water applied to cultivated fields. Conversely, the extraction of water from private and public tube wells was the discharge component of the study. Groundwater levels increased during the Kharif season but decreased during the Rabi season. Average recharge contribution from rainfall was 45 and 14% during the Kharif and Rabi seasons, respectively. The total annual recharge from watercourses and irrigation fields was estimated to be approximately 33% of the total recharge. Rainfall was the most significant source of long-term seasonal recharge, followed by watercourses and irrigation fields. In general, the average depletion of the reservoir was 94 million cubic meters per season.
Lessons learned from a Tiger Worm Toilet implementation project in Sierra Leone
Authors: Sioné Laure , Bastable Andy , Ampilan Abdullah , Templeton Michael R.
Published: July 2023

This paper discusses the implementation of Tiger Worm Toilets (TWTs) as a sustainable alternative to pit latrines in areas with challenging environmental conditions. The study was carried out in Koinadugu, Sierra Leone, where TWTs were installed in 200 households, providing safe sanitation for approximately 1,200 individuals within a 17-month period. The study reveals that TWTs offer several benefits over traditional pit latrines, including higher cost efficiency. Despite some setbacks, TWTs have been well-received by the local communities, resulting in a significant reduction in open defaecation in areas where latrines are not viable. The study presents areas of further research and concludes with recommendations for future TWT designs based on the lessons learned.
Study on Gamma selection in the optimal operation of secondary water supply system based on deep Q-learning network
Authors: Geng Weimin , Yan Jun , Xie Shanbin , Zhang Dian
Published: July 2023

When the requirements for water pressure and quantity of drinking water for residents and industrial buildings exceed the capacity of the urban water distribution system, a secondary water supply system (SWSS) is supplied to users by pipelines through storage, pressurization, and other facilities. In China, SWSS has been installed in 97% of residential buildings and the operation of SWSS is directly related to the water pressure and water quality of the users' tap water. In this paper, the operation optimization objectives for the SWSS with storage facilities were proposed, and deep Q-learning network (DQN) was applied to optimize the control of SWSS. In this study, the pressure, the water age in the roof water tank, and the power consumption of the pumps were selected as the optimization objectives. The equation for the qualitative selection of the key hyperparameter (Gamma) was proposed and verified by the experiments in a community of City S in East China. The results indicated that with the decrease in the volume of the water tank, the larger Gamma value was recommended, and the more future conditions were considered. It is hoped that the result can be used as a reference in SWSS operation optimization.
Potential uses of Topical Resiquimod for Mycosis Fungoides Tumor Stage
Authors: Boretti Alberto
Published: August 2023

Introduction:

Resiquimod (formula C17H22N4O2, ChEMBL Id 383322) is an immune response modifier that stimulates immune responses to tumor lesions mostly through toll-like receptors (TLR) 7 and 8 dependent pathways.

Methods:

This study considers the potential use of Resiquimod in the topical treatment of myco-sis fungoides tumor stage, for which standard-of-care is radiation therapy which has a very well-known dosage-effects relationship and efficacy, but also side effects, and also the limitation re-garding the number of times a same area can be treated during a lifetime.

Result:

Trials are suggested to evaluate the use of Resiquimod as a replacement for radiation therapy in case of shallow lesions, as well as a supporting agent to increase the efficacy and re-duce the dosage of the radiation therapy, lessening the side effects, and permitting many more uses for a same treatment zone.

Conclusion:

This study proposes more research for the possible use of Resiquimod in the standalone or synergetic treatment of MF tumor phase, as there is potential, but not yet evidence, for these uses.
To evaluate safety and efficacy of Keshohills hair oil in subjects with mild to moderate hair fall and dandruff
Authors: Ajitkumar Mandlecha  , Gous Shaukatali Mujawar
Published: July 2023

Introduction - Hair fall is one of the minor diseases which is affecting approximately 1.7% of the world population and challenging task for physicians. Treating Hair issues with ayurvedic medicated oils have gained importance due to the safety and efficacy of their use. Keshohills hair oil is Ayurvedic proprietary medicine formulated as oil with herbs aimed at reducing hair fall and scalp dandruff. Objective - The aim of this clinical study was to evaluate the effectiveness of Keshohills hair oil  in the management of hair fall and dandruff of the scalp in adults. Materials and Methods -   50 healthy respondents were enrolled and completed the period of study positively. The 60 Second Hair Comb Test, Adherent Scalp Flaking Score, Objective Hair Assessment Questionnaire, were used in the study. Conclusion - Keshohills hair oil was effective in reducing hair loss, treating Seborrheic dermatitis.
Samskara (Karana) as a process, its types & effect on Dravya : Review
Authors: Komalben Chavda  , Ashok Kumar Sharma  , Rekh Raj Meena  , Ayushi Nigam
Published: July 2023

Health as well as diseases is dependent on various factors. According to Acharya Charak, the body is supported by three sub-pillars known as Tri Upstambha (Ahara, Nidra, and Brahmacarya). Ahara has been placed first in this statement, which shows that it is most important to maintain the life. Everyone desires a blanched diet. Ahara is responsible factor for human beings, in health and diseased state. Ahara is not only needed for the continuity of life, but also for Bala, Varna, Upacaya and longevity etc. In other medical sciences, food is considered important, but not the manner of eating and cooking. Ahara is a basic need for survival of life. For intake of Ahara, Ayurved has enlisted some special conditions which need to be followed to obtain complete benefits of the food. They are called as Ahara Vidhi Vishesha Ayatan. In which Karana is the processing of the substances which result in transformation of the inherent attributes in Dravya. In this article we will discuss the Samskara as a Karana among Ashta Ahara Vidhi Visheshayatana for maintenance of healthy life as well as management of disease.
A conceptual study on an Ayurvedic perspective in prevention and management of COVID-19 with reference to Charak Samhita
Authors: Ingale Amruta
Published: July 2023

Introduction: This paper correlates the vastly detailed concepts of Janpadodhwansa and COVID- 19 from Charak Samhita to the novel coronavirus. The aim of this paper is to draw the attention of the experts toward the similarities between coronavirus and Ayurvedic preventive measures, in hopes of finding some more effective measures of prevention as well as cure for the ongoing pandemic. The descriptions of Janpadodhwansa are scattered in different Ayurvedic classics which reveals the rich knowledge of the Ayurveda developed since the time immemorial. Aim & Objective: To review the well documented concept of the Ayurveda about Janpadodhwansa and its preventive and supportive management as in present era of COVID-19 pandemic. Materials & Methods: A brief description was given about Adharma and immunity. The concept of pandemic/epidemic is explained with the term “Janpadodhwans.” Literary study of COVID-19 through the perception of classical disquisition like Charak Samhita, Sushrut Samhita of Ayurveda with the available commentaries, with modern correlation was done. Conclusion: It was deduced that every disease changes its mode of onset and course of progression with changing climatic conditions and timeline peculiarities. The diseases are not identical, but the author hopes that the similarities drawn can be of use to better understand the whole spectra of diseases that have come and those that have yet to come.
An overview of Kustha and its management approaches in Ayurvedic texts
Authors: Kuldeep  , Sheetal Verma  , Sakshi Awasthi  , Vikas
Published: July 2023

Our skin serves as a barrier to ward off numerous outside intrusions. The body's skin is the only organ that is easily visible to the eyes. The largest organ and one that is most vulnerable to illness and damage is the skin. Skin is an indicator of normal physiology and expresses emotions due to its visibility. It connects the internal and exterior environments and houses the complexion that preserves personality and beauty. In the society, it helps people develop their own identities. A homeostatic imbalance in the body may be the cause of changes in skin colour. Skin health is influenced by a variety of interconnected elements, including diet, hygiene, circulation, age, immunity, genetics, psychological state, and medication. Skin is referred to as 'Twacha' or 'Charma' in Ayurveda. Twacha is derived from the Sanskrit term Dhatu - Twach Samvarne, which means body covering. The broad categories of Kushtha have been used to discuss all skin conditions in Ayurveda. The seat of Sparshajnanendriya, one of the Vata Jnanendriyas, is Twacha, and it is the largest of the five Jnanendriyas.
Menstruation myths and facts - A Review Article
Authors: Bhalgat Madhuri  , Shailaja Gulabrao Salunkhe
Published: July 2023

Menstruation is a phenomenon that only affects women. It has, however, always been surrounded by myths and taboos that keep women from participating in many facets of sociocultural life. The subject has always been taboo in India. Menstruation-related taboos, which are prevalent in many civilizations, have an impact on girls' and women's emotional well-being, attitude, way of life, and, most significantly, health. The difficulty of confronting the menstrual taboos and cultural stereotypes is made even more difficult by the lack of knowledge and awareness about puberty, menstruation, and reproductive health among females. So, in order to fight these problems, a strategic strategy must be taken. The purpose of the current study is to highlight menstruation-related stereotypes that are widespread in India, how they affect women's lives, and how important it is to address these concerns in primary care.
Medicinal use of poisonous plant Arka its pharmacological study
Authors: Mamta  , Ritu Kapoor  , Manoj Adlakha
Published: July 2023

A poisonous plant is one that, when touched or consumed in large enough quantities, can be hazardous or lethal to humans or other animals. These plants can be utilized as herbal medicines with therapeutic effects when used in the right proportions and in small doses. One of the herbs listed in all of the old Ayurvedic texts is Calotropis procera. In Ayurveda, it is referred to as Arka. In many traditional medical systems, the various portions of the plant are used to cure a wide range of illnesses, including worm infestation, strangury, and ulcers. Ascites, anasarca, intestinal worms, skin diseases, and cough have all been treated with the root bark. The root-powered can treat cancer, scrotal enlargement, piles, boils, dyspepsia, gastroenteritis, dysentery, and dyspepsia. Science-based pharmacological screens have been used by researchers to confirm the effectiveness of the compound. According to pharmacological studies, Calotropis procera Linn. exhibits a wide range of biological activities, including those that are hepatoprotective, cytotoxic, anti-diabetic, analgesic, anti-inflammatory, anti-arthritic, antioxidant, anthelmintic, wound healing, and anti-tumor. Details regarding the plant are documented in Ayurvedic botanical literature such as Dhanwantari Nighantu, Madana Pala Nighantu, and Bhavaprakash and therapeutical literature in Charak Samhita, Sushrut Samhita. This review presents pharmacognostic, pharmacological, and traditional uses of Calotropis procera.
Aromatherapy: A New Pragmatism in Dentistry [Part-2]
Authors: Supriya PR  , N Nandan , N Sunil Raj , C Anitha , Vishwanathan Soundarya
Published: July 2023

A new and alternative way to reduce anxiety levels in dental clinics is the use of aromatherapy. Aromatherapy uses plant materials and aromatic plant oils, including essential oils and other aroma compounds for improving psychological or physical well-being. Number of studies has been done to prove the therapeutic properties of various essential oils, but very few have been published on their use in dentistry.  This review is a continuation of previous article which will provide an overview of remaining essential oils, including their therapeutic properties and applications in dentistry.
A correlative study of Shosha, As a ‘Rasavaha Srotovidda Lakshana’ with emaciation caused by ‘Short Bowel Syndrome’
Authors: Shivanand Ganachari
Published: July 2023

Human body is made up of numerous channels of transportation through which the Dhatus circulate. These channels are termed as ‘Srotas’. The concept of Srotas is explained very scientifically and distinctly in Ayurvedic texts. It is stated that, any corporeal entity do not arise or decay without the Srotases. There are divergent opinions regarding the number of Srotas. Charaka has explained 13 Srotas while Sushruta has mentioned 11 pairs of Srotas. Rasavaha Srotas, as explained by both the Acharyas, has its root in Hridaya and Rasavaha Dasha Dhamani. This particular Srotas is concerned with the absorption of Ahararasa and nourishing the subsequent Dhatus. When the Srotas is vitiated due to various causes, the nutrition to the subsequent Dhatus is disturbed, which may lead to the depletion of Dhatus resulting into Shosha i.e., emaciation. The ‘Short Bowel Syndrome’ is a disorder clinically defined by malabsorption, diarrhoea, steatorrhoea, malnutrition as well as fluid and electrolyte disturbances. All these conditions give rise to the malnourishment leading to the condition called ‘emaciation’. The clinical findings of emaciation resemble the signs and symptoms of Shosha explained in Ayurveda as a Viddalakshana of Rasavaha Srotas. Since the malabsorption is a common finding in both, the disorder emaciation can be correlated with Shosha. In this article, an attempt has been made to establish the co-relation between the Shosha due to the vitiation or injury to Rasavaha Srotas with its applied aspects.
Unlocking the therapeutic potential of Millets: A path to Diabetes Control
Authors: Mansoria Poornima , S.B. Singh
Published: July 2023

Diabetes mellitus is a global health concern, with a rising prevalence and significant implications for public health. Lifestyle factors, including diet, play a crucial role in the development and management of diabetes. In recent years, there has been a growing interest in the potential of incorporating millets into dietary interventions for the prevention and management of diabetes. Millets, traditional grains rich in fibers, minerals, and photochemicals, offer promising nutritional benefits and unique therapeutic properties that may positively impact blood glucose control and reduce the risk of diabetes-related complications. This manuscript reviews the existing literature on the role of millets in the prevention and management of diabetes mellitus, highlighting their potential mechanisms of action, impact on glycemic control, and implications for dietary recommendations.
To evaluate safety and efficacy of Arthrohills oil in subjects with Musculoskeletal Pain
Authors: Ajitkumar Mandlecha  , Gous Shaukatali Mujawar
Published: July 2023

Musculoskeletal pain affects bones, joints, ligaments, tendons or muscles. An injury such as a fracture may cause sudden, severe pain. According to the World Health Organization (WHO), 20-33% of the world’s population has some form of chronic musculoskeletal pain, translating to 1.75 billion people globally. Outdoor patients, having chronic pain of musculoskeletal origin were advised Arthrohills oil external application locally as few drops for small joints and up to 2–3 ml for the larger joints once in a day for external application with gentle massage for 15 min up to 6 weeks were used in this study. Assessment points were Pain, Tenderness, Swelling and Joint motility. We can conclude that, effect observed in all parameters is significant. Arthohills oil was safe and effective in musculoskeletal pain.
A review on Gandhak Vati : An Ayurvedic formulation in patients of Agnimandya and Ajeerna
Authors: Nakhat Mal  , Divya Singh  , Sanjay Kumar
Published: July 2023

Nearly 70% of Ayurvedic pharmaceutical formulations are of herbo-mineral origin, and Gandhakvati is one such formulation that is offered in traditional Vati (tablet) form. In practise, it is mostly utilised in the Ayurvedic medical system to treat digestive issues. Here, a number of references to Gandhakvati are gathered from Ayurvedic data sources such traditional texts and lexicons and then thoroughly examined in terms of ingredients, ratio, dose, and their indications. According to the classics, it has more therapeutic uses in Agnimandya. There are around nine formulations with the name Gandhakvati that are listed in various ancient books, each with a unique set of ingredients and therapeutic properties.
Exploring the Agada perspective of Vatsanabha
Authors: Priyanka  , Vanya Gupta  , Aditi Yadav  , Priyanka Sharma
Published: July 2023

Ayurved is a comprehensive system of natural health care that originated in the ancient Vedic times of India. Its primary emphasis is on prevention of disease and maintenance of health. Ayurved is the science of life that is widely practiced in India. It used medicine prepared from plants, animals and mineral origin. All the three sources of drugs can be divided under poisonous and nonpoisonous category. Vatsnabha (Aconitum ferox) is categorized under the Sthavara Visha. Even a strong poison can become an excellent medicine if administered properly; on the other hand even the most useful medicine act as a poison if not handled correctly. Vatsnabha is highly toxic in nature even then it is used as a medicine after purification and in therapeutic dose. Shodhana or purification is the process which involves the purification as well as reduction in the levels of toxic principles thus removing the untoward effects the drug produce. In therapeutic doses it has capacity to treat many diseases therefore; it is used as an ingredient of various Ayurvedic formulations. Ayurved proposes a traditional technique of Shodhana to reduce the harmful effects associated with Vatsnabha. The present review article gives us opportunity to understand the therapeutic uses, toxic effects, methods of purification, antidotes and medicolegal aspect of Vatsnabha.
Ayurvedic management of Vicharchika (Eczema) - A Case Report
Authors: Dija T Lawrence  , Anand R J  , Girish K J  , Tapas Brata Tripaty
Published: July 2023

Eczema is a reaction pattern manifested by variable clinical and histologic findings. Primary lesions may include papules, erythematous macules and vesicles which can coalesce to form patches and plaques. In severe eczema, secondary lesions such as weeping and crusting may predominate. Eczema has quite resemblance with Vicharchika in Ayurveda. Vicharchika is characterized by skin manifestation having the symptoms Kandu (Itching sensation), Pidika (Papule), Shyava Varna (Blackish brown discoloration) and Bahusrava (Excessive exudation). Case summary: A 62 year old male patient approached with chief complaints of diffuse scaly skin lesions over face, upper limbs, lower limbs, abdomen and flanks associated with severe itching and serous discharge since 8 months. The Ayurvedic diagnosis was made as Vicharchika (Eczema) on the basis of signs and symptoms. The patient was given with Raktha Shodhaka and Kushtahara Shamana Aushadis (Oral medications) along with Parisheka (Sudation by shower sprinkling) with Sidharthaka Snana Choorna as Sravahara line of management. Later on Sadyovirechana was administered for Koshta Shudhi. From the 7th day Abhyanga (Oil massage) was started and on 11th day of treatment Siravyadha (Bloodletting) was done. Significant improvement was observed after 14 days of treatment in terms of EASI Score. This case study shows that Ayurvedic treatment is helpful in effective management of Vicharchika and helps in improving the quality of life.
Invitro-Antimicrobial Activity of Shirish Twak (Albizia lebbeck)
Authors: Surekha Khot  , Manjula Turamari  , Aishwarya Sangolagi
Published: July 2023

Staphylococcus aureus is primary pathogen of humans and also of animals, and its infections are found throughout the world. It causes many clinical conditions such as skin infections, pyogenic infections and systemic infections like bacteremia, osteomyelitis, septic arthritis, endocarditis, pneumonia, meningitis, deep seated abscess, and also toxin mediated infections like food poisoning, toxic shock syndrome, staphylococcal scalded skin syndrome. Human cases and carriers are reservoir of this infection. This bacterium has penicillin and methicillin resistance. 7.7 million deaths around the world were found linked to bacterial infection. That is 13.6%, or 1 in 8, of all global deaths. This makes bacterial infections the second leading cause of death globally. There are large differences in burden as well as distribution of bacterial pathogens across regions. As there is no effective immunization with toxids or bacterial vaccines against S.aureus. The drug Shirish (Albezia lebbeck) is coated as superior amongst all anti-poisons drugs by Acharya Charaka, Shirish is having properties like Vishagna, Kandughna, Kshtaghna, Charmarogahara, Varnya karma, and having chemical compositions like saponins, tannins, d-catechin, d-leucocyanidin, frieedlan-3-one and y-sitosterol and these possess antioxidant anti-inflammatory, anti-allergic actions. So, this drug was selected for study.
Effect of Shashti Shali Pinda Swedan and Sahchar Tail Matra Basti in the management of Young Onset of Parkinson Disorder (YOPD) - A Case Report
Authors: Chhaya Baghel  , Babita Dash  , Harsha Gupta
Published: July 2023

The young onset Parkinson disease is a progressive neurodegenerative disease characterized by both motor and non motor features. The diseases affect families and caregivers through its progressive degenerative effect on mobility and the muscle control.[1] The main difference between young onset of Parkinson disorder (YOPD)and the late onset of Parkinson disorder (LOPD) is genetic etiology and clinical symptoms e.g., dystonia and levodopa induced per dyskinesia are common in YOPD. YOPD person carrying  a greater social economic burden compared to late onset of Parkinson disease due to age factor. YOPD Patients more prone to levodopa related motor complication. Parkinson’s disease is referred to in the ancient Indian medical system of Ayurveda under the name Kampavata which is characterized by Kampa (Tremors), Stambha (Rigidity), Chesthahani (Akinesia) & Gativikriti (Gait Disorders). The case study is of a 45 years old male who has been diagnosed with early stage idiopathic Parkinson’s disease. No satisfactory treatment is seen in contemporary system of medicine so treatment is planned in here study.
Management of Pilonidal Sinus with Chitraka Kshara Sutra - A Case Study
Authors: Gowthami N  , Shailaja S.V
Published: July 2023

Pilonidal sinus means nest of hairs also called Jeep-bottom because it was very common in jeep drivers. It is an acquired condition commonly found in hairy males. Different surgical methods have been described for this disease such as excision and primary closure and excision with reconstructive flap, etc. However, the recurrence after surgery is very high. There is similarity between Pilonidal sinus and Shalyaja Nadi Vrana described in Sushruta Samhita. Acharya Sushruta has described minimally invasive Para surgical procedure viz. Kshara Sutra for Nadi Vrana (Pilonidal sinus). This treatment not only minimizing the complications and recurrence but also enables the patient to resume work quickly with less discomfort. The patient attended Shalya Tantra OPD of Sri Kalabyraveshwara Ayurvedic College was treated with the Chitraka Kshara Sutra. The patient recovered well with complete excision of the tract within span of seven weeks.
Ayurvedic management of Keratoconus - A Case Report
Authors: Anuj Kumar Singh  , Veena Shekar
Published: July 2023

This study reports a case of 37 years old female who had presented with the complaints of blurred vision in left eye for distant objects and also frequent headache and photophobia on exposure to bright light with heaviness in both of the eyes. The subject approached us with the reports of already performed corneal topography where corneal ectasia could be appreciated in both the eyes. The subject was already diagnosed as Keratoconus at previous hospital where she had consulted before. Ayurvedic treatment was initiated with Basti, Nasya, local ocular therapeutics which included Pindi, Bidalaka, Netra Prakshalana and Tarpana. The subject reported reduction in symptoms within 3 months of the treatment. It was observed that there was no progression of the disease from the findings of corneal topography which was repeated after the treatment within 3 months of initial visit.
A fundamental study of the Science of Life vs. Death w.s.r. to Indriya Sthana
Authors: Kanyal Kavita , Puspa Priyadarshini  , Shambhu Kumar Suman  , Pallavi Bharti  , Vijay Shankar Pandey
Published: July 2023

Having a long, vice-free life is seen as a great blessing by many people, especially those who idealize Ayurveda. With this if we find out how long we have left to live or when we will pass away then it seems very pleasant and amazing. It can appear magical to the common man but through the lens of Ayurveda it becomes plausible. Ayurvedic principles provide a comprehensive understanding of the different aspects of life, including the causes and symptoms of aging, as well as ways to maintain good health and treat disorders through wellness practices and therapy. While clearly describing the examination of Kumar Ayu in Sharer Sthana and of the remaining Ayu in Indriya Sthana, a detailed explanation has been presented on the fundamentals and applied aspect of science of life in Sharer Sthana and science of death in Indriya Sthana. It is not possible to achieve meaningful longevity without analyzing the causes of death. Changes in the natural expressions of the body are considered to be Arishta. Arishta can provide time-bound knowledge of death as well as its causes. The absence of the same symptoms that give knowledge of death, provides the knowledge of life. If the Varnadi Parikshya Bhaavas placed in Purush has a clearly articulated Arishta it is impossible to avoid that Arishta. One can view death in a positive light and by thoroughly examining and managing the situation patient, their families, doctors, and hospitals can reduce stress on the healthcare system and save time and money during pandemics like COVID-19. By studying and utilizing Indriya Sthana or Arishta Vigyaan doctors can gain more knowledge and increase their efficiency.
Review of Trivrit (Operculina turpethum) in Brihatrayi
Authors: U. Gayathri Sameera  , A. Vijaya Lakshmi  , G. Swarupa Rani  , P. Suguna Jyothi
Published: July 2023

Trivrit (Operculina turpethum) was considered as Agra Dravya among Ayurvedic classics apart from Sukha Virechana Karma it has many therapeutic uses and it is mentioned in treatment of Kusta, Kamala, Anaha, Visarpa, Grandhi etc. and various Yogas (medicinal preparations) were mentioned in classical books like Charaka Samhitha, Sushrutha Samhitha, Astanga Hridaya, Sarangadhara Samhitha, Nighantus etc. it has got many important chemical constituents and various research studies were conducted on it for its wide range of health benefits.
OKUL, EV VE ÖĞRENCİ ÖZELLİKLERİNİN 4. SINIF ÖĞRENCİLERİNİN TIMSS 2019 MATEMATİK BİLİŞSEL BECERİLERİNDEKİ ROLÜ
Authors: Ayva Yörü Fatma Gökçen , Sezer Başaran Elif , Çakan Mehtap
Published: July 2023

Bu araştırma TIMSS 2019 Türkiye uygulamasında okul, ev ve öğrenci özelliklerinin 4. sınıf öğrencilerinin matematik bilişsel becerilerine etkisini incelemek amacıyla yapılmıştır. Yordayıcı korelasyonel deseninin kullanıldığı araştırmanın örneklemini TIMSS 2019 Türkiye uygulamasına katılan 4. sınıf düzeyindeki 3539 öğrenci, 173 öğretmen ve 173 okul oluşturmaktadır. Veri toplama aracı olarak öğrenci, ev, okul ve öğretmen anketleri kullanılmıştır. Grup-içi ve gruplar-arası düzeyinde modellerin test edilmesinde çok düzeyli yapısal eşitlik modellemesi uygulanmıştır. Araştırma sonucunda grup-içi düzeyinde kurulan modelde bağımlı değişken (bilme, uygulama, akıl yürütme) için açıklanan varyans sırasıyla %31,7, %31,8 ve %29,5’tir. Grup-içi düzeyinde kurulan modellerde değişkenler arasındaki en yüksek standartlaştırılmış yol katsayısı okula başlayan öğrencilerin görevlerini yapması ve okulöncesindeki ebeveyn aktiviteleri arasındadır. Gruplar-arası düzeyinde kurulan modelde bağımlı değişken (bilme, uygulama, akıl yürütme) için açıklanan varyans sırasıyla %59,8, %62,7 ve %55,7’dir. Gruplar-arası düzeyinde kurulan modellerde değişkenler arasındaki en yüksek standartlaştırılmış yol katsayısı bilişsel beceriler ile ev kaynakları arasındadır.
Çocukluk Çağında Karaciğer Hemanjiyomu Tanısıyla Takip Edilen Hastaların Tiroit Fonksiyon Testlerinin Değerlendirilmesi
Authors: Kılıçlı Evrim , Köksal Yavuz
Published: July 2023

Amaç: Bu çalışmanın amacı hemanjiyom tanısı alan hastalarda tiroit fonksiyon testlerinin değerlendirilmesidir.

Gereç ve Yöntemler: Ekim 2010-Ekim 2022 yılları arasında hemanjiyom tanısı ile takibe alınan ve tanı anında tiroit fonksiyon testleri bakılmış olan 20 hastanın dosyaları retrospektif olarak incelendi. Hastaların demografik ve klinik özellikleri ile görüntüleme ve laboratuvar bilgileri not edildi.

Bulgular: Çalışmaya dahil edilen 20 hastanın 13’ü (%65’i) kız ve 7’si (%35’i) erkekti. Hastaların yaşı 4 gün ile 16,5 yıl arasında değişiyordu (ortanca, 20 ay). 10 hasta (%50) infanttı. 3 hasta (%15) preterm iken, 17 hasta (%85) termdi. Karaciğer hemanjiyomu 17 hastada tesadüfen bulunurken (%85), 2 hastada (%10) karın ağrısı ve 1 hastada (%5) ise antenatal tanı ile saptanmıştı. Karaciğerdeki hemanjiyom boyutları 4 ile 50 mm arasında değişiyordu (ortanca 10 mm). Hastaların tiroit fonksiyonları incelendiğinde 19 hastada (%95) tiroit fonksiyonları normal iken 1 hastada (%5) subklinik hipotiroidi olduğu saptandı.

Sonuç: İnfantil hepatik hemanjiyoma bağlı hipotiroidizm için çalışmalar yetersiz olup hangi tip infantil hepatik hemanjiyomda hipotiroidinin görülme riskinin arttığı tam olarak belirlenene kadar takipte hipotiroidi gelişebileceği akılda tutulmalıdır.
Effect of different bacterial contamination on experimental adhesive intestinal obstruction in rats
Authors: Demirtaş Gökhan , Çalışkan Doğuş , Celepli Pınar , Hücümenoğlu Sema , Tiryaki Tuğrul
Published: July 2023

Aim: Postoperative peritoneal adhesions (PPA) cause pain, intestinal obstruction and infertility after abdominal surgery and to date there is no shown pathogenesis or definitive treatment. One of the most important points in intraabdominal interventions is bowel flora and its effect on infection. It was thought that different microorganisms found in flora or frequently added as hospital flora might cause inflammatory processes and cause PPA formation. There are a lot of studies showing intraabdominal infections cause PPA but there is no study comparing the effect of different bacterial strains on PPA formation. That is why we designed this study using the most common microorganisms isolated in intraabdominal infections and hospital flora. In this study, we aimed to investigate the effect of different bacterial strains (Klebsiella spp, E. coli spp, anaerobe) on the formation and degree of PPA in adhesion formation in rats.
Methods: In this study, rats were divided into 5 groups, consisting of twelve rats. Groups were classified as; E. coli, Klebsiella, Bacteriodes fragilis, Sham and Control groups. The rats were sacrificed on the fourteenth day and relaparotomy was performed. The results were evaluated macroscopically and microscopically according to the previously determined classifications.
Results: When bacterial infected groups were compared with sham and control groups, both microscopic and macroscopically significant increase in PPA was observed.
Conclusion: In the experimentally generated adhesion model, microorganisms have been found to play an active role in PPA formation. But there was no significant difference between bacterial strains on PPA formation.
Evaluation of Demographic, Clinical Characteristics and Laboratory Values of Pediatric Patients Followed in Palliative Care
Authors: Sargın Fatma , Değirmencioğlu Sinan , Sevgili Ali , Çelik Jale Bengi
Published: July 2023

Background/Aims: The importance of pediatric palliative care centers, which we think is insufficient both in the world and in our country, is increasing. The aim of this study is to reveal the demographic, clinical and laboratory characteristics of pediatric patients followed in a palliative care center.
Methods: In this retrospective study, demographic data (age, gender), laboratory findings (platelet, mean platelet volume, lymphocyte, neutrophil counts, glucose, sodium, potassium, urea) of pediatric patients followed up in an adult palliative care center between 18.10.2018 and 15.01.2023, creatinine, albumin and the C-reactive protein, CRP/albumin ratio, platelet/lymphocyte ratio and neutrophil/lymphocyte ratio) and clinical features (length of stay in PCU and survival) were evaluated.
Results: It was determined that 61 pediatric patients between the ages of 2-17 were followed up in the palliative care center between 18 October 2018 and 15 January 2023. 65.6% of the patients were male and 6.6% were Syrian citizens. The duration of stay in the palliative care center was between 1-64 days. While 16.4% of the patients had tracheostomy, 14.8% needed home mechanical ventilator. Only 3 (4.9%) patients received parenteral nutrition. The diagnosis of admission to the palliative care center of 47 (77.0%) patients included in the study had neurological sequelae after head trauma. The mortality rate was 1.6%.
Conclusions: It is obvious that the centers are insufficient in the face of the increasing need for pediatric palliative care. Although adult palliative care centers are compensating for this deficiency at this stage, it is clearly seen that the number of pediatric palliative care centers should be increased in the future.
The Effect of Rosmarinic Acid Against Ovarian and Lung Injuries Induced by Ovarian Torsion Detorsion in Rats
Authors: Tanyeli Ayhan , Ekinci Akdemir Fazile Nur , Güzel Derya , Erdoğan Kardelen , Eraslan Ersen , Bilgin Gökhan , Güler Mustafa Can
Published: July 2023

Background: Here, we purposed to find out the effects of two different Rosmarinic acid (RA) doses against lung injury caused by ovarian ischemia-reperfusion. Materials and Methods: We planned the groups as sham, ovarian torsion detorsion (O/TD; 3hours torsion/3hours detorsion), RA 40 mg/kg (40 mg/kg RA+O/TD), and RA 80 mg/kg (80 mg/kg RA+O/TD) groups. Following the experimental procedure, we sacrificed the rats and then, collected the lung and ovarian tissues for biochemical evaluations. Result: Total oxidant status (TOS), myeloperoxidase (MPO) activity, malondialdehyde (MDA) levels, and oxidative stress index (OSI) were elevated in the O/TD group compared to the sham group. These parameters declined due to low and high doses of RA administration. Total antioxidant status (TAS) level and superoxide dismutase (SOD) activity diminished in the O/TD group while increasing in RA treatment groups. However, the high dose of RA treatment group enhanced the antioxidant activity further and reduced the oxidant parameters compared to the low dose RA treatment group. Conclusion: In this study, RA treatment reduced O/TD-induced ovarian and lung injuries in the experimental animals.
Inclusive Digital Financial Services for Persons with Disabilities: Impact on Economic Empowerment and Financial Inclusion
Authors: Santoso Bagus
Published: July 2023

Financial inclusion has emerged as a policy concern in many countries, leading to various initiatives to promote financial inclusion for marginalised populations, including persons with disabilities (PwD). This research examines the usage of financial services by PwD in developed and developing countries through a systematic literature review (SLR) and relevant descriptive statistics. The findings shed light on significant barriers hindering PwD to financial services, such as information asymmetry, complex banking procedures, insufficient sensitivity towards disabilities that result in less accommodating financial services, and limited innovation in banking services. The findings suggest that improving financial literacy and adopting inclusive digital financial services are keys to improving financial inclusion for PwD.
Some Basic Results in ν-Normed Spaces
Authors: Rohman Minanur , Eryılmaz İlker
Published: August 2023

In this paper, we introduce the notion of a directed preserving generator (d.p.g.) from R into R. This d.p.g. can be used to construct new fields which generally have the same properties as R, except that some properties are affected by d.p.g. itself. With this new field, a ν-normed space will be formed. Some of the basic properties of this normed space are also discussed.
Ontological model of knowledge as the basis for automation of the process of distribution of quotas for the extraction of aquatic biological resources and control over the level of their development
Authors: Oleynikova A. V. , Oleynikov A. A.
Published: August 2023

Objective. In this paper, the process of developing an ontological model of knowledge of state control bodies in the field of quotas for the extraction of aquatic biological resources is considered. The need to develop this model arose due to the insufficient level of automation of knowledge extraction from data collected and processed manually from eighteen territorial departments of the Federal Agency for Fisheries. Insufficient speed of collecting and processing data on the current level of industrial production of aquatic biological resources may cause incorrect planning during the subsequent distribution of catch quotas, which may lead to a decrease in biological diversity in the reservoirs of the Russian Federation with the subsequent loss of types of aquatic biological resources.Method. The study used methods of analysis of theoretical and regulatory documentation, analysis of statistical data, as well as secondary data analysis.Result. An object ontological model of knowledge of state control bodies in the field of quotas for the extraction of aquatic biological resources has been developed.Conclusion. The developed ontological model makes it possible to accelerate the extraction of knowledge from aggregated data on the level of distribution and development of quotas for catching aquatic biological resources, and also serves as the basis for creating a full-fledged information system for accounting for the extraction of aquatic biological resources and monitoring their population.
Model of trusted interaction of agents in decentralized cyber-physical environmentv
Authors: Petrenko V. I. , Tebueva F. B. , Struchkov I. V. , Ryabtsev S. S.
Published: August 2023

Objective. The purpose of the work is to increase the efficiency of the functioning of agents of a cyber-physical system in the presence of agents with incorrect or malicious behavior. The goal is achieved by establishing a trusted interaction between agents and quick detection of malicious impact.Method. Trusted interaction is carried out using distributed ledger technology and agent confidence indicators. The novelty of the proposed solution lies in the fact that information about the actions of agents is stored and aggregated using smart contracts at specified time intervals. Each agent keeps a local copy of the agent interaction chain. If several agents interact with each other, then they exchange information stored in their copies of the ledger.Result. To test the proposed method, we implemented it in C++. For the experiments, the scenario of collective perception by agents of a decentralized cyber-physical environment in a specialized simulation program Contiki Cooja was used.Conclusion. The method implemented using the solutions proposed in this work showed higher efficiency than the method based on the dynamic calculation of the confidence index. The proposed solutions can be applied not only in cyber-physical systems, but also in any other systems with decentralized control.
Assessment of information security risks of automated system using neuro-fuzzy logic
Authors: Aydinyan A. R. , Tsvetkova O. L.
Published: August 2023

Objective. Automated systems are widely used in production, and an important criterion for their reliability is information security. The aim of the study is to provide a balance between possible losses as a result of the implementation of threats and the cost of protection tools that reduce risks using neuro-fuzzy logic.Method. The developed model is based on the use of fuzzy logic.Result. A model of integrated information security risk assessment has been obtained, which can be practically applied for a comprehensive analysis of the effectiveness of organizing a protection system for automated systems operating in various fields of activity. The risk indicators of information security of an automated system, described with the help of linguistic variables, are revealed. Based on these indicators, information security risk assessments were obtained from the state of: software; technical support; information support; organizational and methodological support; the level of training and motivation of employees. The fuzzy production rules of the model are formulated to determine the integrated assessment of the information security of an automated system, providing a full account of all factors that have a significant impact on the level of security of an automated system.Conclusions. A feature of the proposed approach is the formalization of the assessment process, reducing the level of subjectivity in the formation of risk assessments.
Telephone-Based Intervention to Improve Family Planning Care in Pregnancies of Unknown Location: Retrospective Pre-Post Study
Authors: Flynn Anne Nichols , Koelper Nathanael C , Sonalkar Sarita
Published: July 2023

Background

Patients followed for a pregnancy of unknown location are generally followed by a team of clinicians through telephone calls, and their contraceptive needs at the time of pregnancy resolution may not be addressed.

Objective

This study aimed to assess contraceptive counseling and contraceptive uptake before and after a telephone-based intervention.

Methods

This was a retrospective pre-post study assessing pregnancy intendedness in patients with a pregnancy of unknown location and the proportion of patients who received contraceptive counseling and a contraceptive prescription before and after the initiation of a telephone-based intervention. We reviewed medical records 1 year before and 1 year after implementation of our intervention for demographic characteristics, pregnancy intendedness, pregnancy outcome, contraceptive counseling documentation, receipt of contraception, and repeat pregnancy within 6 months. We assessed the effects of an implementation strategy to address family planning needs once pregnancy was resolved by comparing the proportions of patients who were counseled and received contraception before and after our intervention was implemented. We performed logistic regression to identify associations between covariates and the outcomes of contraceptive counseling documentation and receipt of contraception.

Results

Of the 220 patients in the combined cohort, the majority were Black (161/220, 73%) and ultimately had a resolved pregnancy of unknown location (162/220, 74%), and the proportion of pregnancies documented as unintended was 60% (132/220). Before our intervention, 27 of 100 (27%) patients received contraceptive counseling, compared with 94 of 120 (78%) patients after the intervention (odds ratio [OR] 9.77, 95% CI 5.26-18.16). Before the intervention, 17 of 90 (19%) patients who did not desire repeat pregnancy received contraception, compared with 32 of 86 (37%) patients after the intervention (OR 2.54, 95% CI 1.28-5.05). Our postintervention cohort had an increased odds of receiving contraceptive counseling (OR 9.77, 95% CI 5.26-18.16) and of receiving a contraceptive prescription (OR 2.54, 95% CI 1.28-5.05) compared with our preintervention cohort.

Conclusions

We found that over half of patients with a pregnancy of unknown location have an unintended pregnancy, and standardization of care through a telephone-based intervention improves contraceptive counseling and prescribing in patients with a resolved pregnancy of unknown location. This intervention could be used at any institution that follows patients with a pregnancy of unknown location remotely to improve care.