bluuebunny/crossref_metadata_2025 huggingface dataset:
Supportive care against correcting protein-energy malnutrition in patients with generalized gastrointestinal cancer
Authors: Petrova O. M. , Lipatov O. N. , Kudryashova L. N.
Published: January 2023

Introduction. A decrease in nutrition of cancer patients affects all vital functions of the body, which is, according to numerous studies, typical of patients with gastrointestinal disturbances.

Materials and methods. The study was set out to investigate the effect of correcting protein-energy malnutrition on the symptoms manifestation, including pain, fatigue, sleep disorder, poor appetite, nausea, vomiting, constipation and diarrhea in patients with generalized forms of gastrointestinal cancer. The study involved questionnaire method applied prior to the study and three months after. Three groups, equivalent in terms of selection criteria, participated in the study. For this purpose, the study participants were given nutridrink compact protein and omega-3 polyunsaturated fatty acid.

Results and discussion. This study found out that timely nutritional support contributes toward reducing the negative symptoms of cancer and, when combined with supportive care and pain management, leads to significantly better results in terms of improving quality of life.

Conclusion. Timely nutritional support has a positive effect on reducing the negative symptoms associated with cancer (pain, fatigue, sleep disorder, poor appetite, nausea, vomiting, constipation and diarrhea), and, along with supportive care and pain management, improves the quality of life more significantly.
Anterior abdominal wall reconstruction in patients with midline ventral hernia
Authors: Timerbulatov M. V. , Shornina A. S. , Lihter R. A. , Kaipov A. E.
Published: January 2023

Introduction. Simultaneous hernio-abdominoplasty allows solving a complex of problems of the anterior abdominal wall in one surgical intervention. Th e relevance of this issue is determined by the lack of a unified algorithm for solving the combinations of anterior abdominal wall pathologies and by the presence of a number of complications, both in isolated and combined surgical techniques.

Aim. The present paper analyzes the treatment results of patients undergoing simultaneous surgery for ventral hernia and deformations of the anterior abdominal wall.

Materials and methods. Th e study enrolled 17 women (mean age 35.6 ± 7.0) undergoing inpatient and outpatient treatment in the Department of Plastic Surgery, Mother and Child Clinical Hospital, Ufa, in the period from 2019 to 2022. All patients had various aesthetic deformations of the anterior abdominal wall (laxity and excess skin, skin-fat apron, diastasis of the rectus abdominis muscles, excessive fat deposits) and midline ventral hernia of various sizes. 100 % patients had a history of pregnancy and childbirth; 64.7 % – grade 2 and 3 obesity.

Results and discussion. Two cases (11.76 %) showed local complications as hematoma of the epigastric region and necrosis of the navel. In the first case, this can be explained by the fact that extensive liposuction of the anterior abdominal wall was performed, and in the second – by the presence of a multidefect ventral hernia of large size, in particular, an umbilical hernia with dimensions of 15x8 cm. Complications were mitigated on an outpatient basis within a period of 1.5 to 3 months by means of conservative therapy and physiotherapy.

Conclusion. All patients were satisfied with the obtained aesthetic result
Possible applications for combined lenvatinib and pembrolizumab in advanced endometrial carcinoma
Authors: Menshikov K. V. , Sultanbaev A. V. , Musin Sh. I. , Menshikova I. A. , Sultanbaeva N. I. , Izmailov A. A. , Fatikhova A. A. , Lipatov D. O. , Serebrennikov G. A.
Published: January 2023

Endometrial cancer is one of the most common gynaecological cancers in both the United States and the Russian Federation, and the rate continues to rise. Although early-stage endometrial cancer is associated with a favourable 5-year survival rate (96%), this rate in patients with distant metastases accounts for only 18%. A combination of paclitaxel and carboplatin is standard first-line therapy for advanced, recurrent and metastatic endometrial carcinoma. Pembrolizumab, a monoclonal antibody targeting the programmed death-1 receptor, is approved for therapy of metastatic solid tumors with high microsatellite instability that have progressed aft er previous therapy and have no alternative treatment options. Lenvatinib is an oral multikinase inhibitor that blocks vascular endothelial growth factor receptors 1-3, fibroblast growth factor receptors 1-4, platelet-derived growth factor receptor alpha, RET and KIT. Phase II and III studies (KEYNOTE-146/ Study111 and KEYNOTE-775) on the combination of lenvatinib and pembrolizumab in advanced endometrial carcinoma, irrespective of MMR and MSI status, have shown new potential for the treatment of this pathology. Th e results obtained, including progression-free and overall survival, allow the combination of lenvatinib and pembrolizumab to be considered a new standard for the treatment of this pathology.
HIV-associated lymphomas
Authors: Dudina G. A. , Mabudzada Ch. K. , Ogannisyan A. A. , Nemikin V. N.
Published: January 2023

A steady worldwide increase in the number of people living with HIV (PLHIV) and diagnostic methods requires a separate review of patient-specific nosologies, including lymphoproliferative diseases, some of which are directly associated with the virus due to its oncogenic effect and those that do not relate directly to HIV but introduce nuances to diagnostic and therapeutic approaches when a patient is HIV-positive. Towards this, the paper generally reviews lymphomas in PLHIV, presents the WHO classification of HIV-associated lymphomas, describes a contemporary view of the known mechanisms of pathogenesis, including the role of opportunistic infections, and general principles of diagnostic and therapeutic tactics, provides recommendations on modifying the doses of chemotherapy correlated with the immune status and on preventing CNS involvement. Specific types of lymphoma (Burkitt’s lymphoma, diff use large B-cell lymphoma) are considered separately, including those most frequently associated with patients living with HIV (primary effusion lymphoma, plasmablastic lymphoma, primary central nervous system lymphoma), but rare in the uninfected population.
Preventing postoperative complications after robot-assisted transabdominal preperetoneal repair: clinical case
Authors: Sharafutdinov D. M. , Shavaleev R. R. , Kabirov I. R. , Pavlov V. N.
Published: January 2023

Introduction. Inguinal hernia repair is one of the most common elective surgeries today. In our clinic, the majority of inguinal hernia repairs are performed laparoscopically. The most frequent complication after transabdominal preperitoneal inguinal hernia repair is postoperative seroma.

Materials and methods. A 35-year-old patient C. with a right-sided inguinal hernia sought medical care in our clinic. He underwent robot-assisted TAPP with fluorescence lymphography using indocyanine green (ICG).

Results and discussion. The present paper describes the possible relationship between intraoperative damage of the lymphatic vessels within the spermatic cord induced by robot-assisted transabdominal preperitoneal inguinal hernia repair and postoperative development of inguinal seroma. 5 mg/ml of indocyanine green was injected into the testicle on the side with the hernial bulge to visualize the lymphatic vessels. In this case such procedure is safe and feasible. Due to the tight fusion of the hernia sac with two visualized lymphatic vessels, they were excised during surgery. In the early postoperative period, an ultrasound scan revealed a subclinical seroma in the inguinal region of approximately 10 ml.

Conclusion. A case series of ICG fluorescence lymphography during robot-assisted TAPP should be performed further to elucidate the relationship between lymphatic vessel damage and hydrocele.
Pancreatic islets as a SARS-CoV-2 target
Authors: Vorobеva O. V.
Published: January 2023

Aim. The study is aimed at describing pancreatic islets as one of the SARS-CoV-2 targets.

Materials and methods. The object of the study was the pancreas. The study involved histological staining.

Results and discussion. The autopsy study revealed the signs typical of bilateral viral interstitial pneumonia. Histological examination revealed alveoli with disatelectasis, intra-alveolar edema, hyaline membranes in a part of alveoli. The pancreas histological examination showed hemorrhages, necrotic areas of the islets and detected the following DIC signs: small hyaline thrombi in the heart cavities and large vessels, petechial hemorrhages in the internal organs and adrenal glands, foci of adrenal cortex necrosis with perifocal infiltration (Waterhouse—Friderichsen syndrome); as well as signs of necronephrosis with fibrinoid areas of necrosis in the glomerular capillary network and perivascular lymphoid infiltrates.

Conclusion. SARS-CoV-2 was revealed to target human pancreatic islets, where areas of necrosis developed.
Study of the mortality rate in pre-fattening pigs
Authors: Novotný Jaroslav , Grivalský David , Krepelková Zuzana , Bardová Katarína , Zigo František
Published: January 2023

The focus of this experimental work was the long-term analysis of the mortality of pigs in the pre-fattening category, as well as the determination of the most important etiological and predisposing factors of death. We carried out this research on farm in the east of Slovakia, in the Spiš region, over a period of three years. Based on our 36-month monitoring of pig mortality, we found that pre-fattening mortality was on a downward trend with mortality rates of 2.79%, 2.72% and 2.71% in consecutive years. There is also a certain seasonal impact on mortality in pre-fattening, because we found a higher incidence of deaths especially in the cold spring, autumn and winter months. Diseases such as respiratory and diarrheal diseases were among the most important etiological and predisposing factors of mortality in the observed farm.
Effects of Rice Combine Harvester on Postproduction Losses and Production Costs: The Case of Luzon, Philippines
Authors: Malanon Hernaiz G. , Cruz Renita SM. Dela
Published: January 2023

This study quantified the effects of rice combine harvester (RCH) on rice output particularly on harvesting-threshing losses and production costs. The postproduction losses using different models of RCH were established following a randomized complete block design with two replications and these were compared with the traditional method of harvesting and threshing rice. Partial budget analysis was employed to determine the benefits derived by farmer-adopters using the data gathered from a one-shot cross sectional survey involving 448 respondents. Results of the field experiments revealed that postproduction losses with the three models of RCH did not differ significantly, ranging from 1.19% to 1.76% of the total yield.  Comparing the harvesting-threshing losses in using RCH and the traditional method, the use of RCH significantly reduced harvesting-threshing losses by 1.02 percentage points. Prevention of postharvest loss was more pronounced during the wet season harvest at 1.54 percent. From the point of view of the farmer-adopters, the use of RCH lowered harvesting costs by PhP 3,908.60/ha/ and gained additional PhP 718.40/ha for losses prevented by using RCH. Thus the farmer-adopter could potentially gains additional benefit of PhP 4,627.00/ha/cropping season. With these, the use of RCH has the potential to enhance rice competitiveness by lowering the production cost and preventing paddy loss by PhP1.12/kg or 9.56% of the current production cost.
Efficacy of Different Anaesthetics on Depth of Anaesthesia and Hematological Parameters of Pigs
Authors: Link Robert , Reichel Peter , Oslancova Jana
Published: January 2023

Four groups of piglets were included in the experiment. In each of the experiments, we applied azaperone as the first premedication drug in the 2nd group 4 mg/kg body weight and in the other groups 5 mg/kg body weight. In experiment no. 1, we subsequently administered diazepam (1 mg/kg, i.m.) and ketamine (10 mg/kg, i.m.) to the piglets. In experiment no. 2, we applied xylazine (2 mg/kg, i.m.) and ketamine (20 mg/kg, i.m.). In experiment no. 3 we used diazepam (1 mg/kg, i.m.), xylazine (2 mg/kg, i.m.) and butorphanol (0.2 mg/kg, i.m.). In experiment no. 4, we administered xylazine (2 mg/kg, i.m.) and butorphanol (0.2 mg/kg, i.m.) to piglets. We applied the mentioned drug combinations intramuscularly in the area of ​​the neck muscles. Subsequently, in each of the experiments, we performed epidural anesthesia using 2% lidocaine, in a dose of 1 ml/40 cm of body length.
After putting the animals under anesthesia, we recorded breathing and pulse frequencies, body temperature and checked reflex responses at time intervals. We performed a zero blood collection before the application of the first drug, the first collection after anesthesia and then a second collection the next day, in order to determine the hematological profile. From the conducted experiments, we assessed the relationship of the used combinations of substances to the course and depth of anesthesia and, according to the hematological profile, we evaluated the effect of these substances on specific hematological parameters.
We recorded the longest duration of anesthesia in the first experiment when one of the piglets had disappeared pedal reflexes even after 90 minutes. On the contrary, the shortest anesthesia was during the third experiment, when all piglets reacted 60 minutes post-lidocaine. During experiments 1 and 3, we noticed a significant drop in body temperature compared to the reference values. In a short time interval after the lidocaine administration, the reflex of the pelvic limbs completely disappeared in all tested subjects in each of the experiments.  In experiment no. 3, at time 5 minutes post lidocaine administration, the nasal reflex and the reflex of the forelegs were also negative in all animals. In all tested subjects, 30 minutes after the epidural anesthesia was performed, we observed a negative reflex of the pelvic legs during the second and third trials. During experiment no. 3, we also observed a negative nasal reflex and a reflex of the front legs in the majority of the tested animals in the mentioned time interval.
Effect of Reduced Crude Protein Level on Fecal Nitrogen Excretion and Blood Profile in Finishing Pigs
Authors: Bujňák Lukáš , Naď Pavel , Mihok Tomáš , Hreško Šamudovská Alena , Zigo František
Published: January 2023

The purpose of this experiment was to evaluate the effects of a low-protein diet on the selected variables of protein and energy metabolism in the blood serum as well as on the indicators of fermentation in the faeces (fecal crude protein, ammonia, pH, volatile fatty acids, and dry matter). Twelve finishing pigs (initial body weight: 64.6 ±  3.35 kg) were randomly divided into two groups and fed basal diets with crude protein (CP) levels of 13.6% and 15.4%, respectively. The Lysine, Methionine, Threonine, and Tryptophan levels in the 13.6% CP group were the same as those in the 15.4% CP group after the addition of four crystalline amino acids—Lysine, Methionine, Threonine, and Tryptophan to the diet. The blood and faeces samples were taken from the cranial vena cava and from the rectum at the end of the study period (44 days). The results showed that with the decrease in dietary CP level from 15.4% to 13.6% (a decrease of 1.8%), the fecal crude protein, the fecal ammonia, as well as the blood urea level decreased in the experimental group compared to the control group (P< 0.05 and 0.01, respectively).
Ochratoxin Incidence in Poultry Feed Mixtures
Authors: Harčárová Michaela , Naď Pavel , Zigo František
Published: January 2023

Ochratoxin is one of the most frequently occurring mycotoxins in food and feed. In humans and animals, it is the cause of health disorders, mycotoxicosis. Monitoring the content of ochratoxin in food and feed is an important part of preventive measures. This work was focused at determining the concentrations of ochratoxin in complete feed mixtures for broilers and turkeys by ELISA analysis. The presence of ochratoxin in concentrations lower than 2 ppb was confirmed in the examined samples. The ochratoxin content limit for supplementary and complete feed mixtures for poultry, which represents a value of 100 ppb in feed with a moisture content of 12%, was not exceeded in the samples.
Energy Profile in Broiler Chickens Fed with Different Levels of Humates
Authors: Marcin Andrej , Naď Pavel , Gancarčíková Soňa , Bujňák Lukáš , Skalická Magdaléna , Zigo František
Published: January 2023

The objective of the study was the evaluation the effects of the peroral intake of humates (HS) added into feed mixtures on the energy metabolism of broiler chickens (Cobb 500). The selected parameters are concentrations of glucose, triglycerides and cholesterol analysed in the blood serum. There were used four groups of birds (A, B, C, negative control; n=120) in the experiment. Chickens were fed with ground diets (starter HYD1, grower HYD2, finisher HYD3) with supplements of HS from day 1 to 37 as follows A: Humac nature (HN) 7 g/kg, B: Humac nature monogastric (HNM) 7 g/kg, C: HNM 5 g/kg feed (Humac Ltd., Slovak Republic). The diets had the following content of crude protein: HYD1 230.20, HYD2 222.20, HYD3 209.40 g CP /kg dry matter). The statistical evaluation of results was performed by one-way analysis of variance and means were compared by the Student-Newman-Keuls test and correlation analysis. Higher concentrations (P<0.05) of triglycerides in blood serum were analyzed in groups A or B by 0.24 and 0.26 mmol/l, respectively, in comparison to the control group (y = 0.35830x + 0.58324). The values of cholesterol were at a lower level (P<0.05) in all 3 experimental groups by 1.07, 0.54 and 0.84 mmol/l (y = - 1.18073x + 2.75772). The positive effect of the intake of HS on glucose concentration was not confirmed when a higher concentration (P<0.05) was analyzed in the blood serum of the control group compared with groups A or C by 3.31 and 4.56 mmol/l (y = - 4.06420x + 13.37519), respectively.
Peran Guru Bimbingan dan Konseling Membantu Siswa Kelas XII Menentukan Jurusan Ke Perguruan Tinggi
Authors: Efani Risfa Gusnur
Published: January 2023

Kelas XII merupakan masa dimana siswa harus sudah mempersiapkan studi ke jenjang perguruan tinggi. Karena pada masa ini, siswa akan dihadapkan dengan pertimbangan memilih jurusan yang sesuai dengan minat dan bakat yang siswa miliki. Akan tetapi, masih banyak siswa kelas XII yang belum bisa menentukan jurusan karena kurangnya rasa percaya diri dan belum sepenuhnya memahami minat dan bakat yang dimiliki. Oleh karena itu, dalam hal ini peran guru bimbingan dan konseling dibutuhkan untuk melakukan bimbingan pemilihan jurusan (educational guidance).

Metode penelitian ini menggunakan metode pendekatan Kualitatif dengan jenis penelitian deskriptif. Data berasal dari data primer dan sekunder. Adapun hasil dari penelitian ini adalah guru bimbingan konseling dapat memberikan informasi tentang jurusan di perguruan tinggi, memberikan bimbingan berupa bimbingan kelompok, individu dan spiritual, menyelesaikan perbedaan pendapat antara siswa dan orang tua mengenai pemilihan jurusan.
Konseling Interpersonal dalam Menumbuhkan Kesehatan Mental Korban Bullying
Authors: Rahma Allya , Istima Fatan , Addinullah Moh Aziz , Nihayah Ulin
Published: January 2023

Bullying is an act of aggression committed by someone ora group of people committed against another person and committed repeatedly to harm others physically and mentally. Bullying can affect others who feel harassed, bullied, feared, and without the power to fight the perpetrator. Bullying behavior is divided into a variety of physical bullying, verbal bullying, online bullying, and even cyberbullying. Bullying may occur because of such factors as ward factors, family factors, behavior or personality factors, and the role of peers. Research methods used to write this journal are studies of literature based on case studies. Analysis reveals that the effects of bullying, affecting mental health, and this can be counseled behavior and interpersonal realities to prevent the disparity caused by bullying.
Hubungan Antara Resiliensi dengan Peran Ibu Pada Anak Penyintas Bencana di Hutan Lere
Authors: Gustina
Published: January 2023

This study departs from the assumption that in order for survivors to rise from stress, they need support from their families, especially mothers, in increasing the resilience of survivors. The formulation of the problem from this research is how is the relationship between resilience and the role of mothers in disaster survivors in Lere Huntara. The method used in this thesis research is a quantitative research method, using data collection techniques through questionnaires or questionnaires as data collection techniques. This research was conducted at Lere Huntara. The population in this study were children who survived the disaster in Lere Huntara with the criteria for children who were in the age range of 7-12 years and domiciled in Lere Village, West Palu District, Palu City. The collected data was then analyzed by testing the validity, reliability testing, and testing assumptions using SPSS 16 for Windows assistance techniques. The results obtained based on the results of statistical data analysis obtained a value of Tcount 1.609 < Ttable 1.687 and has a significant value (sig) 0.117 in the Coefficients table with a value of (significant level) 0.05, meaning 0.117 > 0.05 then it can be interpreted that there is no there is a significant correlation between resilience and the role of mothers in Child Survivors in the Lere Huntara. Another finding of this study is based on the results of interviews conducted by researchers that in general the child survivors in Lere Huntara are not cared for by their parents.
Peran Guru Bimbingan Konseling dalam Meningkatkan Self Control Siswa di SMK Negeri 1 Sarjo Kabupaten Pasangkayu
Authors: Jamaruddin  , Syamsuri  , Alimuddin Nurwahida
Published: January 2023

Adapun yang menjadi fokus utama dalam penelitian ini adalah (1) bagaimana self control siswa di SMK Negeri 1 Sarjo Kabupaten Pasangkayu, (2) bagaimana peran guru bimbingan konseling dalam meingkatkan Self Control siswa di SMK Negeri 1 Sarjo Kabupaten Pasangkayu, dan (3) apa faktor pendukung dan penghambat guru bimbingan konseling dalam meningkatkann Self Control siswa di SMK Negeri 1 Sarjo Kabupaten Pasangkayu. Metode yang digunakan dalam penelitian ini adalah metode penelitian kualitatif dengan teknik pengumpulan data melalui wawancara, observasi, dan dokumentasi guna mendapatkan data yang benar-benar falid dan dapat dipertangggung jawabkan.

Hasil penelitian ini menunjukkan bahwa Self Control Siswa di SMK Negeri 1 Sarjo Kabupaten Pasangkayu yaitu dengan adanya hubungan antara siswa dengan siswa, hubungan antara siswa dengan guru. Adapun peran guru bimbingan konseling dalam menigkatkan Self Control siswa yaitu dengan melakukan tindakan preventif, tindakan kuratif dan tindakan pembinaan. Dan faktor pendukung guru bimbingan konseling dalam meningkatkan Self Control Siswa di SMK Negeri 1 Sarjo Kabupaten Pasangkayu yaitu keaktifan guru wali kelas dan peran orang tua siswa, guru bimbingan konseling bekerja sama dengan guru-guru dan orang tua siswa. Sedangkan faktor penghambat guru bimbingan konseling dalam meningkatkan Self Control Siswa di SMK Negeri 1 Sarjo Kabupaten Pasangkayu yaitu berasal dari faktor internal siswa dan faktor eksternal siswa itu sendiri.
Cannabidiol in the context of sleeping disorders-induced oxidative stress
Authors: Jîtcă George , Ősz Bianca Eugenia , Rusz Carmen Maria , Pușcaș Amalia , Tero-Vescan Amelia , Bătrînu Mădălina Georgiana , Ștefănescu Ruxandra Emilia
Published: January 2023

Sleep disorders can be the result of psychiatric or neurological conditions, such as post-traumatic stress disorders, depression, anxiety, Alzheimer’s disease, Parkinson’s disease. At the same time, changes in sleep, known as sleep disorders, are closely related to various metabolic dysfunctions, which in turn are the result of the generation of reactive oxygen species, or otherwise known as oxidative stress. For this reason, cannabinoid derivatives are increasingly used for this purpose. Among the most used are delta-9 tetrahydrocannabinol (THC) and cannabidiol (CBD). These agents interact with the endogenous endocannabinoid system, either by direct action on specific receptors, or by increasing the availability of endocannabinoids, modifying particular mental states (anxiety, depression). The results of the studies specified in this article provide promising evidence regarding the positive effects of CBD, which extend beyond the scope of sleep disorders, with possible applications also in the case of the accumulation of reactive oxygen species.
Unusual case of infrarenal pheochromocytoma developed on ectopic adrenal tissue: An autopsy case report
Authors: Chiciudean Rebeca , Jung Ioan , Bara Tivadar , Gurzu Simona
Published: January 2023

Introduction: Pheochromocytomas are catecholamine-secreting tumors arising from the chromaffin cells of the adrenal medulla. We describe an unusual case of pheochromocytoma located in the infrarenal area and associated with bilateral adrenal hyperplasia.

Case presentation: A 70-year-old patient was admitted for syncope, diaphoresis, and high blood pressure. Computed tomography showed a 73×70×72 mm retroperitoneal mass of the left infrarenal area. High levels of metanephrine and noradrenaline were found in the urine. A tumor resection was performed. A few days after surgery, the blood pressure suddenly decreased and could not be restored, resulting in the death of the patient. Histopathological examination of the surgical specimen revealed a proliferation of monotonous cells, with eosinophilic cytoplasm, round nuclei with prominent nucleoli arranged in clusters, and capsular and vascular invasion. The tumor cells expressed synaptophysin and chromogranin, without positivity for inhibin A or S100 protein. At the autopsy, both adrenal glands showed hyperplasia but unrelated to the tumor mass. The histological aspect, location, and immunophenotype indicated an ectopic infrarenal pheochromocytoma.

Conclusions: In patients with pheochromocytoma developed on ectopic adrenal tissue, clinical management might be difficult, and diagnosis can be sometimes established only based on post-mortem histopathological examination. Autopsy can be extremely useful in such cases with unexplained evolution.
An evaluation of concordance between linear measurements obtained from conventional, digital and reconstructed three-dimensional printed orthodontic models: An in vitro study
Authors: Shetty Shravan , Natarajan Srikant , Nambiar Supriya , Shetty Prithvi , Chengappa Kavery , Shetty Mukul
Published: January 2023

Objective: To evaluate the potential use of digital and reconstructed three-dimensional printed models as an alternative to conventional plaster models by assessing the accuracy of their linear measurements.

Methodology: Pre-treatment plaster models of 45 patients were selected from the archives of the Department of Orthodontics. Each physical plaster model was scanned and digitized using a three-dimensional (3D) laser surface scanning system (inEOS X5, Dentsply Sirona, Bensheim, Germany). The scanned STL files were later used to reconstruct models by 3D printing using Figure4® standalone 3D printer (3D systems, Rock Hill, South Carolina). Measurements of teeth 11 and 16, the transverse width of the upper jaw between the first molars (MM - intermolar width) and canines (CC - intercanine width) were done manually using a digital vernier caliper (Mitutoyo, Kawasaki, Japan), and the CAD Assistant software (Open cascade, Guyancourt, France). Intra examiner data, Intraobserver variability, and measurement accuracy were evaluated using Intraclass Correlation Coefficient (ICC) analysis was done using SPSS 20.0.

Results: The intraclass correlation coefficients were >0.8 indicating high reproducibility and reliability. Significant differences were found between the physical and the digital models but to a small proportion which were deemed not clinically relevant.

Conclusion: Both the digital models and reconstructed three-dimensional printed models using Figure4® technology were clinically permissible in terms of accuracy and reproducibility. The digital storage, transmission, and treatment planning in an environmentally friendly manner should promote digital over conventional records.
Individual Constitutional Complaints in Lithuania: An Effective Remedy to be Exhausted Before Applying to the European Court of Human Rights?
Authors: Pūraitė-Andrikienė Dovilė
Published: January 2023

Although the significance of an individual constitutional complaint mechanism is mostly associated with the national constitutional protection of human rights, it is a no less significant remedy in the context of the international human rights protection system. Individual constitutional complaints can be considered an effective domestic legal remedy to be exhausted before applying to the European Court of Human Rights (the ECtHR). However, the answer to the question of whether proceedings in a constitutional justice institution fall within the scope of such domestic remedies is very complex and may vary from case to case. Whether it will be required to exhaust an individual constitutional complaint procedure before filing a complaint with the ECtHR will largely depend on the legal system of the state and the scope of the powers of the constitutional justice institution.

This article aims to assess whether the individual constitutional complaint mechanism operating in Lithuania could be recognised an effective remedy to be exhausted before applying to the ECtHR.
Label V. Content: The Problem of Non-Recognition of Civil Confiscation Orders in Europe
Authors: Bikelis Skirmantas
Published: January 2023

The paper discusses the problem of non-recognition of civil confiscation orders in Europe. Despite the breakthrough in international cooperation in the freezing and confiscation of crime proceeds in the criminal law domain, the formal approach in some European states destroys the potential of one of the most advanced instruments against crime proceeds—civil confiscation orders. The study offers a comparative analysis of the concepts of the confiscation of crime proceeds within and outside the frameworks of criminal proceedings. The analysis serves as the basis for the discussion of whether there is reasonable ground for the formal distinction between these concepts.

The author concludes that the formal elimination of the civil confiscation orders has no substantial background. The analysis of both extended powers of confiscation in the criminal law domain in Europe and the Lithuanian Law on Civil Confiscation in the light of principles of proportionality and fair proceedings shows that civil confiscation regimes outside the framework of criminal proceedings may provide adequate safeguards to those provided in the confiscation regimes within criminal proceedings.

The paper contributes to the discussion that is relevant to any European state that considers enacting or amending the civil confiscation legal framework or the legal regulation on recognising and executing crime proceeds confiscation orders. The paper elaborates on the approach that could enhance cooperation among European states in the prevention of organised crime.
COVID-19 Affected State Aid Provision in the EU
Authors: Puksas Andrius , Moisejevas Raimundas , Novikovas Andrejus
Published: January 2023

The EU State Aid regulation is based on the premise that the market and the entities within it must operate independently without additional unnecessary intervention by the state. In other words, state intervention must be kept to a minimum. Unjustified aid to one or another entity may distort the situation in the market and lead to a number of undesirable consequences, including market advantage acquired by the aided entity. The willingness of the state and its institutions to help those who face difficulties may be understandable, but not always justified. However, the prohibition on a state and its institutions to grant aid is not unconditional and, in some cases, may cause serious undesired consequences. The coronavirus disease (COVID-19), which hit EU member states in the first half of 2020, led to a re-thinking of the rules in force and a broadening of the scope for state aid exemptions. However, there are a number of questions about the nature of the EU State Aid regulation and its correlation with COVID-19 outbreak-conditioned decisions. The article analyses the state aid granting practices across the EU (including the UK) related to COVID-19. It covers approximately two- year period—from the start of the pandemic in Europe to March 2022.
The role of real estate development activity in the re-urbanization of cities – a case study of Łódź, Poland
Authors: Antczak-Stępniak Agata
Published: January 2023

The suburbanization of cities began in many countries after World War II and was caused, among other things, by the growing popularity of the motor car, the development of transport networks, and the growth in human populations. In post-socialist countries, this process started later (mainly after the collapse of socialism). Suburbanization was often an uncontrolled phenomenon (due for instance to an ineffective urban spatial policy), which contributed to urban sprawl, and in which developers played a significant role. The growing costs of city maintenance have prompted local authorities to undertake planned activities for re-urbanization. The increase in development activities in recent years encourages reflection on their importance in these processes. This article aims to outline the role of developers, responsible for the new construction and the reconstruction of existing facilities, in the process of city re-urbanization, using the city of Łódź, Poland, as a case study. It is an example of a post-industrial city in which, the process of suburbanization, combined with the phenomenon of urban sprawl, proceeded rapidly after 1989. The phenomenon of depopulation has also been observed in Łódź for several years. Therefore, re-urbanization may be an antidote to some of Łódź’s population and spatial problems. The methods of desk research and a case study were used to achieve the aim.
Condition of decommissioned military barracks in Hungary
Authors: Bársony Róbert
Published: January 2023

The reforming of the armed forces caused huge and continuous cuts to the manpower and to the finances. Which resulted of the decommission of numerous barracks throughout the country. The size and structure of these forces was not appropriate for the threats that the country faced, and country did not have the required resources to develop a new form for its armed forces. The aim of this article was to investigate opportunities in the case of decommissioned barracks, which point to the possibility of re-using abandoned buildings and sites and reducing the environmental damage that can still be found there. Due to changes in the economy and society of Hungary at the end of the 20th century, the number of barracks/garrisons and the structure of the Hungarian Defence Forces have changed substantially over the intervening years. Most of the garrisons in the countryside have been downsized by hasty decisions, leaving behind non-utilized and unsalvaged areas and in many cases a vast infrastructural heritage. Opportunities for the utilization of these abandoned facilities and the amelioration of environmental damage must be sought. Therefore, it was necessary to map and investigate the current conditions of these former garrisons. The author visited most of the closed barracks in all the counties of Hungary. The author also searched for information about Hungarian and Soviet barracks and examined the condition of decommissioned barracks at first only the possibility of their utilization was considered, later, an environmental point of view was added.
A high accuracy voltage approximation model based on object-oriented sensitivity matrix estimation (OO-SME model) in electrical impedance tomography
Authors: Gao Zengfeng , Darma Panji Nursetia , Kawashima Daisuke , Takei Masahiro
Published: January 2023

The image reconstruction in electrical impedance tomography (EIT) has low accuracy due to the approximation error between the measured voltage change and the approximated voltage change, from which the object cannot be accurately reconstructed and quantitatively evaluated. A voltage approximation model based on object-oriented sensitivity matrix estimation (OO-SME model) is proposed to reconstruct the image with high accuracy. In the OO-SME model, a sensitivity matrix of the object-field is estimated, and the sensitivity matrix change from the background-field to the object-field is estimated to optimize the approximated voltage change, from which the approximation error is eliminated to improve the reconstruction accuracy. Against the existing linear and nonlinear models, the approximation error in the OO-SME model is eliminated, thus an image with higher accuracy is reconstructed. The simulation shows that the OO-SME model reconstructs a more accurate image than the existing models for quantitative evaluation. The relative accuracy (RA) of reconstructed conductivity is increased up to 83.98% on average. The experiment of lean meat mass evaluation shows that the RA of lean meat mass is increased from 7.70% with the linear model to 54.60% with the OO-SME model. It is concluded that the OO-SME model reconstructs a more accurate image to evaluate the object quantitatively than the existing models.
Pratylenchus araucensis (Rhabditida: Pratylenchidae) a Widely Distributed Nematode in Musa spp. From Colombia
Authors: Arboleda-Riascos C. E. , Riascos-Ortiz D. H. , Varón De Agudelo F. , Mosquera-Espinosa A. T. , Oliveira C. M. G. , Muñoz-Flórez J. E.
Published: January 2023

Pratylenchus is one of the most limiting nematodes of Musaceae production in the world. Knowledge of the nematode species is one of the requirements for its management in the field. This study aimed to identify up to the species level Pratylenchus populations associated with plantain and banana crops in the states of Caldas, Quindío, and Valle del Cauca in Colombia. In these regions, Pratylenchus has been reported to affect these crops in the past, but with records of the nematode only up to the genus level. For this purpose, five populations of Pratylenchus extracted from samples composed of roots and rhizospheric soil, four from plantain and one from banana, were identified through morphological, morphometric, and molecular analysis (sequencing of the D2–D3 of rRNA and cytochrome oxidase subunit I of mtDNA). All populations were identified as P. araucensis, a species reported previously in eastern Colombia, and one that the present study found in the center and southwest of the country, indicating that this species of nematode is widely distributed in the Musaceae-producing areas of Colombia. The present study reports the first COI mtDNA sequences for this species of nematode.
The patient as an aggressor
Authors: Piąta Aleksandra , Kocańda Kamila , Adamczyk-Gruszka Olga
Published: January 2023

Despite the development of medicine, acts of violence against health care professionals, are a current, frequent and widespread phenomenon. In Poland, many health care staff are entitled by law to legal protection provided for public officials. Therefore, criminal offenses against them are more severely punished. In the years 2018-2019, research was carried out on acts of aggression that had been experienced by a group of 249 health care staff in health care facilities in the Świętokrzyskie Voivodeship. Just slightly more than 7.5% of the respondents indicated that they had not experienced aggression, which only confirms the scale of the problem. Therefore, managers of health care facilities should use all possible means to limit the extent of attacks and prevent their possible consequences..
Estimating exposure to extremely low frequency magnetic fields near high-voltage power lines and assessment of possible increased cancer risk among Slovenian children and adolescents
Authors: Zagar Tina , Valic Blaz , Kotnik Tadej , Korat Sara , Tomsic Sonja , Zadnik Vesna , Gajsek Peter
Published: January 2023

Background

Some previous research showed that average daily exposure to extremely low frequency (ELF) magnetic fields (MF) of more than 0.3 or 0.4 μT could potentially increase risk of childhood leukaemia.

Materials and methods

To allow calculations of ELF MF around high voltage (HV) power lines (PL) for the whole Slovenia, a new three-dimensional method including precision terrain elevation data was developed to calculate the long-term average ELF MF. Data on population of Slovenian children and adolescents and on cancer patients with leukaemia’s aged 0–19 years, brain tumours at age 0–29, and cancer in general at age 0–14 for a 12-year period 2005–2016 was obtained from the Slovenian Cancer Registry.

Results

According to the large-scale calculation for the whole country, only 0.5% of children and adolescents under the age of 19 in Slovenia lived in an area near HV PL with ELF MF density greater than 0.1 μT. The risk of cancer for children and adolescents living in areas with higher ELF MF was not significantly different from the risk of their peers.

Conclusions

The new method enables relatively fast calculation of the value of low-frequency magnetic fields for arbitrary loads of the power distribution network, as the value of each source for arbitrary load is calculated by scaling the value for nominal load, which also enables significantly faster adjustment of calculated estimates in the power distribution network.
Osteoarthritis – a multidiciplinary approach
Authors: Bejan Gabriel Cristian , Apostol Ramona , Bejan Mihaela , Grăjdeanu Ioana Veronica , Bădina Mihaela , Simionescu Anca Angela , Stănescu Ana Maria Alexandra
Published: January 2023

Osteoa rthritis is a heterogeneous group of diseases with typical joint damage by articular cartilage damage, along with degenerative changes in the epiphyses of the bones adjacent to the affected joint and the synovial joint.

Osteoarthritis affects people over 50 years, but the onset is much earlier if an occupational factor is present. Due to the high prevalence, osteoarthritis is the leading cause of presentation to primary care, either in the family or occupational medicine. Osteoarthritis also poses an economic burden to society due to direct costs such as the price paid for a visit to the doctor, the cost of drugs or implanted prostheses, or indirect costs generated by decreased fitness for a job or even disability. The occupational medicine specialist has the leading role in primary and secondary prevention in this sense. The collaboration between the family doctor – rehabilitation and occupational physician has the function of tertiary prevention maintaining the quality of life and socioeconomic life in case of these types of patients.
Neurological complications in infection with the SARS-COV-2 virus: Parkinson’s disease and the impact on professional reintegration - case study
Authors: Popa Maria Valentina , Luchian Nicoleta , Gurzu Bogdan , Gurzu Irina Luciana , Duceac Letiția Doina
Published: January 2023

Complications of the SARS-CoV-2 infection have significantly impacted the affected people’s quality of life and professional activity. Neurological manifestations may be present from the onset of infection but also in the course of the disease. The most common neurological symptoms are headache, anosmia/hyposmia, ageusia/dysgeusia, and myalgia. The studies also mention severe complications such as stroke, cerebral hemorrhage, meningitis, encephalitis, Guillain-Barré syndrome, acute transverse myelitis, convulsions, and movement disorders, as the infection with the SARS-CoV-2 virus is affecting both central and peripheral nervous systems. SARS-CoV-2 can worsen the symptoms of Parkinson’s disease, increasing the mortality rate in patients with advanced disease.

The potential risk of inducing Parkinson’s disease has also been suggested, with the virus penetrating the brain where it can trigger cellular processes involved in neurodegeneration. We present you with the case of a nurse in the medical field, without comorbidities, who developed Parkinson’s disease after infection with the SARS-CoV-2 virus. Establishing a cause-and-effect relationship between the onset of Parkinson’s disease and viral infection may be possible, but the mechanisms by which it affects the nervous system and the involvement of the immune system in the pathogenesis of these manifestations are still under study. The progression of the disease, functional status, and ability to work can have a negative impact on professional activity.
The association between lung cancer and silicosis: from theory to practice in occupational medicine
Authors: Oțelea Marina Ruxandra
Published: January 2023

Unbound (free) crystalline-silica dust is recognized since 2012 by the International Agency for Research on Cancer as a class I carcinogen. Exposure to this professional hazard was massive at the end of the last century, and it continues to exist today, albeit at lower levels. The number of cases of occupational cancer attributed to this exposure is minimal in Romania due to the absence of adequate post-exposure monitoring and the reporting of cases that encounters multiple obstacles, such as the absence of exposure data or the disappearance of the industrial sites in which the exposure took place. Occupational exposure to free crystalline silica dust can cause silicosis, and the presence of this disease certifies the existence of significant exposure. That is why the declaration of occupational cancer in a patient previously diagnosed with silicosis should be straightforward because the proof of exposure already exists.

This article presents the cancer-silicosis relationship from the perspective of current scientific data and aims to substantiate the decision of the doctors from the public health departments who investigate and declare the reported cases.
Comparison of Suitable Business Models for the 5th Generation District Heating System Implementation through Game Theory Approach
Authors: Pakere Ieva , Kacare Marika , Murauskaite Lina , Huang Pei , Volkova Anna
Published: January 2023

District Heating and Cooling (DHC) technology is widely recognised as a promising solution for reducing primary energy consumption and emissions. The 5th Generation District Heating and Cooling (5GDHC) network is the latest DHC concept characterised by low-temperature supply, bi-directional heating network operation, decentralised energy flows, and surplus heat sharing. Unlike the 4th Generation District Heating (4GDH) technology, the 5GDHC technology switched to a consumer/prosumer-oriented perspective. The introduction of 5GDHC solutions requires high investments, an important barrier to further developing DHC systems. Therefore, a novel pricing and business model could include introducing co-owners or energy managers into the system. Three different local market business models for 5GDHC at the community level have been tested. The reverse technical and economic simulation has been used for a feasibility study to determine the resources, business models, and combinations closest to the break-even point with lower costs and higher gains for all involved stakeholders.