bluuebunny/crossref_metadata_2025 huggingface dataset:
Transmasculinidades em foco
Authors: Fernandes Sampaio Arthur , Silva Cavalcanti Céu , Rocha Barreto Maria Cristina
Published: June 2024

Este artigo procura analisar as produções acadêmicas sobre homens trans brasileiros que trabalharam com pornografia online. Realizou-se uma pesquisa utilizando-se a plataforma do Google Acadêmico, com um recorte temporal de dez anos (2013-2023), encontrando-se três artigos brasileiros sobre essa abordagem específica, e destes, apenas um discutia sobre homens trans que trabalhavam na atividade. A quase ausência de produções acadêmicas sobre esse assunto leva a quatro linhas de discussões: o fenômeno da diferença da passabilidade de homens e mulheres trans/travestis; o uso, por parte de homens trans, de uma espécie de invisibilidade funcional; a dificuldade de articulação política unificada dos homens trans; e o fato de a maioria dos estudos sobre pornografia serem propostos por estudos feministas. Por essas razões e por se tratar de uma questão complexa, cujas discussões não conseguem se esgotar facilmente, faz-se necessário o fomento à produção de estudos cuidadosos sobre homens trans e pornografia.
Transformações nas ações afirmativas
Authors: Loureiro Thiago , Rejane Salim Natália , Lopes de Almeida Ângela , Borges Melo Flávio Adriano , Sevilha Stofel Natália
Published: June 2024

Este estudo enseja refletir a presença/ausência de pessoas trans nas universidades públicas brasileiras a partir de vivências da equipe da Secretaria de Ações Afirmativas, Diversidade e Equidade de uma universidade federal e de uma transativista. Nossa empreitada experimental é motivada a partir de um lugar comum e de uma tessitura intersubjetiva, na qual buscamos articular reflexões a dados documentais e alguns estudos que consideramos relevantes no campo dos direitos humanos, das ações afirmativas, bem como da comunidade de LGBTQIAPN+ no Brasil, país líder mundial em assassinatos de pessoas trans. Esboçamos um levantamento das universidades que sinalizam ofertar cotas para pessoas trans e consideramos que apesar de alguns avanços alcançados, é evidente o rescaldo de uma cruzada antigênero e de um backlash contra os direitos dessas pessoas, o que nos leva a reivindicar a urgência de ações afirmativas para um público historicamente negligenciado do projeto de desenvolvimento do país.
“Estranhavam o fato de eu não andar de namorado, namorado homem”
Authors: De Oliveira Gomes Joanderson , De Lima Bezerra Silva Fabricio
Published: June 2024

Este texto apresenta a narrativa docente de uma professora do interior paraibano que se declara lésbica. A pesquisa tem por objetivo compreender os caminhos percorridos pela professora Raquel, nossa entrevistada, assim como analisar de que forma suas singularidades contribuíram/afetaram no processo de sua constituição docente, partindo do pressuposto que ser uma professora lésbica traz à tona demandas que a diferem de uma docente heterossexual. Como percurso metodológico, seguimos os caminhos propostos pela História Oral, na perspectiva da recuperação e valorização da memória docente feminina. O estudo sinaliza como a instituição escolar vem histórica e culturalmente se constituindo como um espaço onde a heteronormatividade tem lugar privilegiado, relegando a homossexualidade às margens. Desse modo, o espaço escolar vem se tornando um dos lugares mais difíceis para alguém não heterossexual. Apesar desse cenário, foi possível perceber ainda as rupturas construídas no transitar de nossa participante, bem como a importância do fato de tê-la atuando no espaço público – e educativo. Do mesmo modo, sinaliza-se a urgência de uma formação docente que prepare os(as) professores(as) para lidarem com a diversidade, respeitando toda a sua riqueza e pluralidade.
"Homens que curtem”
Authors: Rios Luís Felipe , Souza Araújo Mateus
Published: June 2024

O texto discute os desafios metodológicos de envolver homens que fazem sexo com homens e com mulheres (HSHMs) nas pesquisas, apontados nos estudos sobre comportamento sexual e epidemia do HIV/aids como fugidios a pesquisadories. Embasado em pesquisa na Região Metropolitana do Recife, argumentamos que a dificuldade está relacionada à operacionalização dos próprios conceitos que orientam o olhar para os territórios onde homens com práticas homossexuais transitam – sociabilidade, região moral, gueto e comunidade – e a facilidade que alguns dos territórios oferece para es pesquisadories realizarem sua tarefa. Do mesmo modo, a nomeação homossexual, presente em termos de consentimento esclarecido, roteiros de entrevista e questionários, pode afastar os HSHMs das pesquisas, que, como mostra nossa etnografia, são descritos como simpatizantes, e se percebem como entendidos, o que os capacita a se engajarem na curtição.
Pedagogias do filme Alice Júnior
Authors: Hundertmarck Katiele , Albuquerque de Boer Raphael
Published: June 2024

O filme Alice Júnior (2019) demonstra conter pedagogias culturais que podem nos inspirar a educar para as sexualidades com as juventudes. Para esse recorte, analisamos determinadas cenas e discutimos como podemos utilizar esse artefato cultural para as práticas educativas. Com a análise e discussão, percebemos que somos interpeladas a problematizar como os nossos corpos, gêneros e sexualidades podem subverter as normas cis-heterossexuais e, assim, enquanto potência de vida, permitir imaginar e construir outros modos de ser e estar. Isso porque é possível pensar em formas de nos relacionarmos sem violências. O filme nos parece oportuno para tensionar as determinadas desigualdades que têm posicionado algumas sujeitas em situações de sofrimentos, bem como nos convida a promover uma educação para as sexualidades, junto das juventudes, que possibilite considerar os marcadores sociais da diferença.
Reading literature as a starting point in the construction of an autoethnographic study on the intersectionality
Authors: Manzoni-de-Almeida Daniel
Published: June 2024

Autoethnography is an important methodology that allows the expression of dissident bodies. The reading of a literary book and the construction of reading diaries, as a starting point for autoethnographic reflection, is still little explored. Here, I start from the question: what is it to be a gay scientist? Starting from this question and the experience of a teacher the proposal of this study was to perform an autoethnographic analysis reading and interpreting The life of Galileo by the writer Bertolt Brecht. To this end, a literary reading journal and an analysis reflecting with theories and these experiences was constructed keeping in mind how the vulnerability of dissident bodies, can be in alliance for the uses and responsible work with sciences. In conclusion, the construction of a 1-year autoethnographic diary of reading a book of literature allowed us to conduct a record, denouement and cultural critique of an important moment, which touches on points of intersectionality, about the context of the covid-19 pandemic.
Experiências juvenis periferizadas sobre gênero e raça
Authors: Ferreira da Costa Aldemar , Pereira Barros João Paulo , Forte Cavalcante Laisa , Lima Gurgel Livia
Published: June 2024

Este artigo visa discutir, a partir das contribuições de Lélia Gonzalez ao campo da psicologia social, as intersecções entre gênero e raça na experiência de jovens negros e negras em contextos periféricos de Fortaleza. Parte-se de uma abordagem qualitativa, explorando estratégias micropolíticas para compreender os impactos da colonialidade de gênero e raça em jovens negros em áreas periferizadas de Fortaleza. As narrativas destacam as assimetrias de gênero e as condições desiguais enfrentadas pelos jovens negros contextos racializados. O artigo ressalta a importância de debater as desigualdades raciais e de gênero, desnaturalizando instrumentos de dominação presentes na estrutura social brasileira. A pesquisa propõe a produção de narrativas desafiadoras aos modos coloniais de dominação, enfatizando a necessidade de epistemologias críticas à colonialidade na psicologia para fortalecer as lutas antirracistas e antissexistas.
Submissas e Orquídeas
Authors: Manuel de Oliveira João
Published: June 2024

Resenha de
PÉREZ NAVARRO, Pablo. Orden y peligro-por uma deslocalizácion queer. Barcelona: Bellaterra. 2023.
Familial concordance for height and its components: Analyses from the breakthrough generations study
Authors: Morris Danielle H. , Jones Michael E. , Schoemaker Minouk J. , Ashworth Alan , Swerdlow Anthony J.
Published: November 2011

Objectives:

To assess familial resemblance for height, arm span, and components of these, and differences between concordance for short and tall heights.

Methods:

We examined whether female relatives were similar for six anthropometric measurements (height, arm span, leg, trunk and arm length, and leg:trunk length ratio). Subjects were 31,622 related individuals aged 16–102 yr participating in the UK Breakthrough Generations Study. Height and arm span were self‐reported, limb and trunk length were measured in a subset (N = 508) by study investigators, and paternal height was reported by the daughter. Data were analyzed using correlations and Poisson regression.

Results:

Correlation coefficients within families were 0.4 for height, 0.3 for arm span, and 0.5 for leg length, trunk length, leg:trunk ratio, and arm length. Women had a relative risk (RR) of being short (i.e., in the lowest height quintile) of 2.3 (95% confidence interval [CI] = 2.1–2.5) if their mother was short, 2.1 (95% CI = 1.9–2.3) if their father was short, and 3.7 (95% CI = 3.4–4.0) if both parents were short. RRs of being tall (i.e., in the highest height quintile) were 2.3 (95% CI = 2.1–2.5), 2.4 (95% CI = 2.2–2.6), and 4.4 (95% CI = 4.1–4.8) if their mother, father or both were tall, respectively.

Conclusions:

We have shown, for the first time, that leg:trunk length ratio and arm length aggregate within families. Concordance seemed to be stronger for tall than short heights. Am. J. Hum. Biol., 2012. © 2011 Wiley Periodicals, Inc.
Melt strength, local velocity, and elongational viscosity profiles of low‐density polyethylene filaments affected by the die design and process conditions
Authors: Sitticharoen Watcharin , Harnnarongchai Wanlop , Intawong Naret , Sombatsompop Narongrit
Published: November 2011

An experimental arrangement to simultaneously measure the melt strength, velocity profiles, and elongational viscosity profiles across the cross section of a molten filament that emerged from either a circular or slit die for low‐density polyethylene (LDPE) under nonisothermal and isothermal conditions is proposed. The proposed experimental rig was based on a parallel coextrusion technique of colored LDPE melt layers into an uncolored melt flowing from the barrel into and out of a die to form a continuous filament before they were pulled down by mechanical rollers until the filament failed. The experimental rig was also equipped with a high‐speed data‐logging system and a personal computer for real‐time measurements. The results suggest that the draw‐down forces changed continuously with changing roller speed, and the velocity profiles of the melt were not uniform across the LDPE filament during the stretching of the melt. Greater draw‐down forces and local melt velocities were obtained in the slit die or under the nonisothermal condition. The draw‐down forces and velocity profiles in both dies were affected by the volumetric flow rates from the extruder and the roller speeds used, with the effect being more pronounced for the circular die. The elongational viscosity profiles of the LDPE filament were not uniform across the filament cross section and corresponded well to the obtained velocity profiles. The elongational viscosities of the LDPE filament were relatively higher when the filament was extruded and stretched in the circular die and under the nonisothermal condition. The changes in the elongational viscosity profiles were more sensitive to changes in the volumetric flow rate and roller speed in the circular die. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Synthesis of novel silica gel immobilized‐calix[4]arene amide ionophores and their anion binding abilities toward phosphate and chromate anions
Authors: Yiǧiter Şengül , Bayrakcı Mevlüt , Ertul Şeref , Yılmaz Mustafa
Published: November 2011

This article describes the synthesis and characterization of four new calix[4]arene ionophores 5–7 and 9 and corresponding two new silica gel‐immobilized calix[4]arene ionophores containing pyridine 10 and 11 via modification of calix[4]arene monoamide derivatives 5 and 6 with aminopropyl silica gel, respectively. The extraction studies have been performed using liquid–liquid extraction for receptors 5–7 and 9 and solid–liquid batchwise sorption procedures for receptors 10 and 11. Obtained extraction results showed that the immobilized‐calix[4] arene ionophores 10 and 11 have high extraction ability toward chromate and phosphate anions as compared to their corresponding monomeric precursors 5 and 6. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Synthesis and characterization of a new family of cationic amino acid‐based poly(ester amide)s and their biological properties
Authors: Song H. , Chu C. C.
Published: November 2011

A new family of positively charged and water soluble amino acid‐based poly(ester amide)s (PEAs) consisting of nontoxic L‐arginine, diols, and aliphatic dicarboxylic acids building blocks was synthesized and characterized. The L‐arginine based PEAs (Arg‐PEAs) were prepared by a solution polycondensation of two monomers: tetra‐p‐toluenesulfonic acids salts or hydrochloride acid salts of bis‐(L‐arginine) α, ω‐alkylene diesters (monomer II), and di‐p‐nitrophenyl esters of saturated or unsaturated dicarboxylic acids (monomer I). Optimal reaction conditions were studied as functions of type of solvents and acid acceptors, concentrations of reactants. The molecular weights (Mn and Mw) of Arg‐PEAs measured by GPC ranged from 20,000 to 60,000 g mol−1 with a rather narrow molecular weight distribution below 1.5. The chemical structures were confirmed by IR and NMR spectra. Arg‐PEAs obtained were all amorphous materials with Tg from 33 to 125°C, depending on the number and the type (saturated vs. unsaturated) of methylene groups in diols or diacids, and the type of counter‐ions attached to the guanidine group of the Arg‐based PEAs. The Arg‐PEAs had a high solubility in all polar solvents, including water. Preliminary studies of cell morphology and DNA capture capability of Arg‐PEAs indicated that this new family of cationic PEAs was nontoxic and more biocompatible than a commercial transfection agent (Superfect®), and can successfully capture plasma DNA. The strong positive charge of Arg‐PEAs as well as their good water solubility could provide unique characteristics for potential gene transfection or other charge preferred biomedical applications. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012
Lithium‐Ion Conducting Electrolyte Salts for Lithium Batteries
Authors: Aravindan Vanchiappan , Gnanaraj Joe , Madhavi Srinivasan , Liu Hua‐Kun
Published: November 2011

This paper presents an overview of the various types of lithium salts used to conduct Li+ ions in electrolyte solutions for lithium rechargeable batteries. More emphasis is paid towards lithium salts and their ionic conductivity in conventional solutions, solid–electrolyte interface (SEI) formation towards carbonaceous anodes and the effect of anions on the aluminium current collector. The physicochemical and functional parameters relevant to electrochemical properties, that is, electrochemical stabilities, are also presented. The new types of lithium salts, such as the bis(oxalato)borate (LiBOB), oxalyldifluoroborate (LiODFB) and fluoroalkylphosphate (LiFAP), are described in detail with their appropriate synthesis procedures, possible decomposition mechanism for SEI formation and prospect of using them in future generation lithium‐ion batteries. Finally, the state‐of‐the‐art of the system is given and some interesting strategies for the future developments are illustrated.
ChemInform Abstract: Phase Equilibria of the Cu—Ni—Si System at 700 °C.
Authors: Sun Weihua , Xu Honghui , Liu Shuhong , Du Yong , Yuan Zhaohui , Huang Baiyun
Published: November 2011

The phase equilibria at the 700 °C isothermal section of the title system are determined by XRD, SEM, optical microscopy, X‐ray spectroscopy, and electron probe microanalysis.
ChemInform Abstract: Low‐Temperature Synthesis of Peony‐Like Spinel Li4Ti5O12 as a High‐Performance Anode Material for Lithium Ion Batteries.
Authors: Li Guanchao , Xia Jian , Jiao Jiqing , Chen Liuping , Shen Peikang
Published: November 2011

The title compound is synthesized from an aqueous solution of hydrous titanium oxide and lithium hydroxide (autoclave, 180 °C, 24 ) followed by calcination of the obtained powder at 400 °C for 2 h in air.
ChemInform Abstract: Hydrothermal Synthesis of Superconductors Ba1‐xKxBiO3 and Double Perovskites Ba1‐xKxBi1‐yNayO3.
Authors: Zhang Ganghua , Li Guobao , Huang Fuqiang , Liao Fuhui , Li Kuo , Wang Yinxia , Lin Jianhua
Published: November 2011

Ba1‐xKxBiO3 (x = 0.05, 0.35, 0.5,0.55), BaBi0.75Na0.25O3, and Ba0.85K0.15Bi0.83Na0.17 O3 are hydrothermally synthesized from aqueous solutions of Bi(NO3)3, Ba(NO3)2, NaBiO3, and KOH (autoclave, 180 °C, 1—5 d) and characterized by SEM, powder XRD, and magnetization measurements.
ChemInform Abstract: Two Novel 2D Organic—Inorganic Hybrid Lacunary Keggin Phosphotungstate 3d—4f Heterometallic Derivatives: [Cu(en)2]2H6 [Ce(α‐PW11O39)2] ·8H2O and [Cu(dap)2(H2O)][Cu(dap)2]4.5 [Dy(α‐PW11O39)2] ·4H2O.
Authors: Shi Dongying , Chen Lijuan , Zhao Junwei , Wang Yu , Ma Pengtao , Niu Jingyang
Published: November 2011

Compounds (IV) and (VI) are characterized by powder and single crystal XRD, and IR spectroscopy.
ChemInform Abstract: Kopsihainanines A and B, Two Unusual Alkaloids from Kopsia hainanensis.
Authors: Chen Jia , Chen Jian‐Jun , Yao Xiaojun , Gao Kun
Published: November 2011

The absolute konfiguration of compound (!) is assigned based on ECD calculation.
ChemInform Abstract: Synthesis and Application of Modified Silica Sulfuric Acid as a Solid Acid Heterogeneous Catalyst in Michael Addition Reactions.
Authors: Zolfigol Mohammad Ali , Veisi Hojat , Mohanazadeh Farajollah , Sedrpoushan Alireza
Published: November 2011

The use of the modified, nonvolatile, inexpensive, and safe catalyst in the Michael addition reaction with indole (I), pyrrole (VI), and thiols (VIII)/(XI) is presented.
ChemInform Abstract: Gold‐Catalyzed 1,3‐Acyloxy Migration/5‐exo‐dig Cyclization/1,5‐Acyl Migration of Diynyl Esters.
Authors: Leboeuf David , Simonneau Antoine , Aubert Corinne , Malacria Max , Gandon Vincent , Fensterbank Louis
Published: November 2011

Gold‐catalyzed cycloisomerization of heptadiynyl esters, e.g. (I), (III) or (V), proceeds with an unprecedented 1,5‐sigmatropic acyl shift.
ChemInform Abstract: A Novel Method for Introducing a Polyfluoroalkyl Group into Aromatic Compounds.
Authors: Tahara Ryuhei , Fukuhara Tadahito , Hara Shoji
Published: November 2011

The introduction of a polyfluoroalkyl group into aromatic compounds (II) is achieved by Friedel‐Crafts reaction using sulfides (I).
ChemInform Abstract: SnCl2/KI‐Mediated Allylation Reactions of Formaldehyde in Water.
Authors: Lin Mei‐Huey , Lin Long‐Zhi , Chuang Tsung‐Hsun
Published: November 2011

The reaction of formaldehyde with allyl bromides affords homoallylic and 2‐halohomoallylic alcohols.
ChemInform Abstract: Double Hydroacylation Reactions of Acyclic and Cyclic α,β‐Unsaturated Aldehydes.
Authors: Cha Kyung‐Mi , Lee Hyejeong , Park Jung‐Woo , Lee Yura , Jo Eun‐Ae , Jun Chul‐Ho
Published: November 2011

The title reaction of acyclic α,β‐unsaturated aldehydes with alkenes leads to two ketone products via 1,4‐addition of a primary amine (CyNH2 or hexylamine) to the aldehyde followed by a retro‐Mannich‐type fragmentation of the resulting β‐aminoketimine intermediates.
ChemInform Abstract: Ruthenium‐Catalyzed Three‐Component Coupling via Hydrative Conjugate Addition of Alkynes to Alkenes: One‐Pot Synthesis of 1,4‐Dicarbonyl Compounds.
Authors: Chen Yiyun , Park Sung Hwan , Lee Chung Whan , Lee Chulbom
Published: November 2011

A terminal alkyne, a vinyl ketone or an acrylate, and water undergo react in the presence of RUP to give the desired 1,4‐diketones with some exceptions.
ChemInform Abstract: Ligand‐Free Nickel‐Catalyzed Conversion of Aldoximes into Nitriles.
Authors: Li Yen‐Ting , Liao Bei‐Sih , Chen Hsin‐Pei , Liu Shiuh‐Tzung
Published: November 2011

An efficient dehydration of a variety of aldoximes is developed using molecular sieves in the presence of an optimized Ni(II) catalyst.
ChemInform Abstract: (+)‐Tartaric Acid‐Catalyzed High Regio‐ and Stereoselective Aminobromination of Olefins.
Authors: Chen Zhanguo , Wei Junfa , Li Wenli , Wang Yun , Zhao Pengfei , Shi Xianying
Published: November 2011

α,β‐Unsaturated ketones, α,β‐unsaturated esters, and simple olefins are easily transformed into vicinal haloamino products with excellent regio‐ and stereoselectivity using TosNH2/NBS as the nitrogen/halogen sources and (+)‐tartaric acid as catalyst.
ChemInform Abstract: Iodoarene‐Mediated α‐Tosyloxylation of Ketones with MCPBA and p‐Toluenesulfonic Acid.
Authors: Tanaka Ayumi , Moriyama Katsuhiko , Togo Hideo
Published: November 2011

4‐tert‐Butyl‐1‐[(hydroxy)(tosyloxy)iodo]benzene, generated in situ, serves as an α‐tosyloxylation reagent for ketone substrates to afford synthetically important subunits for heterocycle synthesis.
ChemInform Abstract: Synthesis of Tetra‐ortho‐Substituted Biaryls Using Aryltriolborates.
Authors: Li Gao‐Qiang , Yamamoto Yasunori , Miyaura Norio
Published: November 2011

Highly hindered biaryls are synthesized under optimized conditions which allow an efficient coupling of the sterically congested reaction components.
ChemInform Abstract: Enhancing Activity of Suzuki Reactions in Water by Using Guanidinium Ionic Liquid Stabilized Palladium Micelle Catalyst.
Authors: Lin Li , Li Yanchun , Zhang Suobo , Li Shenghai
Published: November 2011

A ligand‐free coupling of aryl bromides or chlorides with arylboronic acids is developed using the ionic liquid GIL5 as an additive forming nanometric palladium micelles.
ChemInform Abstract: pH‐Responsive Chelating N‐Heterocyclic Dicarbene Palladium(II) Complexes: Recoverable Precatalysts for Suzuki—Miyaura Reaction in Pure Water.
Authors: Li Liuyi , Wang Jinyun , Zhou Chunshan , Wang Ruihu , Hong Maochun
Published: November 2011

The applied catalytic system can be recycled at least four times.
ChemInform Abstract: Palladium (II) Complexes with the Unsymmetrical H‐Spirophosphorane Ligand HP(OCMe2CMe2O)(OCH2CMe2NH): Synthesis, Structural and Catalytic Studies.
Authors: Skarzynska Anna , Gniewek Andrzej
Published: November 2011

The mononuclear palladium complexes (I) and (II), prepared from the title ligand, catalyze the Heck and Hiyama coupling reactions.
ChemInform Abstract: Efficient Control for the Cationic Platinum(II)‐Catalyzed Concise Synthesis of Two Types of Fused Carbocycles with Angular Oxygen Functionality.
Authors: Kusama Hiroyuki , Watanabe Eiichi , Ishida Kento , Iwasawa Nobuharu
Published: November 2011

The preparation of two types of synthetically useful, oxygenated bicycloundecane derivatives is realized starting from the same cyclohexanone by selection of the vinyl ether and the catalyst.
ChemInform Abstract: An Efficient, Simple, and Scaleable Domino Reaction to Diverse N‐(1‐Oxo‐1H‐inden‐2‐yl)benzamides Catalyzed by HPW@nano‐SiO2 under Microwave Irradiation.
Authors: Rostami Mahboubeh , Khosropour Ahmad R. , Mirkhani Valiollah , Mohammadpoor‐Baltork Iraj , Moghadam Majid , Tangestaninejad Shahram
Published: November 2011

Benzaldehyde and its derivatives react with hippuric acid to give the title compounds (III) and (IX).
ChemInform Abstract: Intramolecular Aromatic Carbenoid Insertion of Biaryldiazoacetates for the Regioselective Synthesis of Fluorenes.
Authors: Kim Jinho , Ohk Youhwa , Park Sae Hume , Jung Yousung , Chang Sukbok
Published: November 2011

Dirhodium acetates or copper triflate catalyze the highly regioisomeric formation of the fluorenes from appropriately substituted biaryldiazoacetates, whereas under thermal conditions a significantly reduced regioselectivity is observed.
ChemInform Abstract: Highly Regioselective and Efficient Synthesis of Aminoepoxides by Ring Closure of Aminohalohydrins Mediated by KF‐Celite.
Authors: Pace Vittorio , Hoyos Pilar , Sinisterra Jose Vicente , Alcantara Andres R. , Holzer Wolfgang
Published: November 2011

Optimized reaction conditions allow the regioselective cyclization of aminochlorohydrins and analogues (III) to give the target compounds without any trace of azetidinols.
ChemInform Abstract: Silver‐Mediated exo‐Selective Tandem Desilylative Bromination/Oxycyclization of Silyl‐Protected Alkynes: Synthesis of 2‐Bromomethylene‐Tetrahydrofuran.
Authors: Lee Hyun‐Ji , Lim Chaemin , Hwang Soonho , Jeong Byeong‐Seon , Kim Sanghee
Published: November 2011

Under optimized conditions using a slight excess of NBS in combination with AgF, mono‐bromomethylene‐substituted furans and pyrans are obtained with high preference over the di‐bromomethylene products.
ChemInform Abstract: Organic Hydrogen Phosphites and Hydrogen Phosphates Catalyzed Friedel—Crafts Amidoalkylation of Indoles with Aryl Aldimines.
Authors: Wang Bei‐Lei , Zhang Jin‐Xin , Li Nai‐Kai , Liu Guo‐Gui , Shen Qi , Wang Xing‐Wang
Published: November 2011

A short optimization reveals HPO(O‐Me)2 and HO‐PO(O‐Ph)2 to be efficient organocatalysts for the process.
ChemInform Abstract: Synthesis of Indoles via Palladium‐Catalyzed C—H Activation of N‐Aryl Amides Followed by Coupling with Alkynes.
Authors: Zhou Feng , Han Xiuling , Lu Xiyan
Published: November 2011

Optimized conditions are elaborated which allow a convenient preparation of indole structures.
ChemInform Abstract: Synthesis of Benzo[c]azocanones and Indeno[1,2‐b]pyrroles from Oxoindanecarboxylates.
Authors: Behler Florian , Habecker Florian , Saak Wolfgang , Kluener Thorsten , Christoffers Jens
Published: November 2011

A series of heterocycles (IV) is obtained by bismuth‐catalyzed Paal—Knorr synthesis from phenacyl‐1‐indanone.
ChemInform Abstract: An Efficient Synthesis of 2‐Arylbenzimidazoles from o‐Phenylenediamines and Arylaldehydes Catalyzed by Fe/CeO2—ZrO2 Nano Fine Particles.
Authors: Behbahani Farahnaz K. , Ziaei Parisa , Fakhroueian Zahra , Doragi Neda
Published: November 2011

An improved synthesis of 2‐arylbenzimidazoles from o‐phenylenediamines and arylaldehydes catalyzed by Fe/CeO2—ZrO2 nano fine particles is presented.
ChemInform Abstract: Platinum‐Catalyzed Synthesis of β‐Keto Tetrahydropyrans and Cyclic Dienolethers.
Authors: Liang Qiren , Qian Mingxing , Razzak Mina , De Brabander Jef K.
Published: November 2011

Zeise′s dimer catalyzes the cyclization of linear propargylic alcohols and esters.
ChemInform Abstract: Design, Synthesis, and Cytotoxic Activity Evaluation of New Linear Pyranoxanthone Aminoderivatives.
Authors: Kolokythas George , Daniilides Konstantinos , Pouli Nicole , Marakos Panagiotis , Pratsinis Harris , Kletsas Dimitris
Published: November 2011

The hydrochlorides of the compounds (IV), the free amines (VIII) and (XIIIa), and the difumarate of the compound (XIIIb) are screened for their in vitro cytotoxicity against the murine leukemia L1210 cell line, human colorectal adenocarcinoma (HT‐29), and human uterine sarcoma (MES‐SA and the multidrug resistant variant MES‐SA/Dx5) cell lines in comparison to the reference drugs mitoxantrone and doxorubicin.
ChemInform Abstract: Using Morita—Baylis—Hillman Acetates of 2‐Azidobenzaldehydes for the Synthesis of 2‐Alkoxy‐3‐cyanomethylquinolines and Alkyl Quinoline‐3‐carboxylates.
Authors: Kim Hea Jung , Jeong Eun Mi , Lee Kee‐Jung
Published: November 2011

In the formation of the unexpected products (VI), the nitro group acts as a leaving group.
ChemInform Abstract: Regio‐ and Stereoselective Synthesis of 1‐Benzopyrano[2,3‐b]pyrrolo[2,3‐d]pyridines: A Microwave‐Accelerated Intramolecular [3 + 2] Cycloaddition Reaction of Azomethine Ylide.
Authors: Maiti Sourav , Lakshmykanth T. M. , Panja Suman Kalyan , Mukhopadhyay Ranjan , Datta Ayan , Bandyopadhyay Chandrakanta
Published: November 2011

The reaction of the compounds (I) with the compound (II) by heating in toluene gives the product (III) in similar yields but in longer reaction times (25‐30 h).
ChemInform Abstract: Synthesis of cis‐4,5‐Diarylazepanes.
Authors: Chang Meng‐Yang , Lee Nien‐Chia
Published: November 2011

The synthesis of title compounds (III) is based on the Lewis acid promoted rearrangement of mesylates (I) followed by catalytic hydrogenation of the resulting intermediates (II).
ChemInform Abstract: NHC‐Cu‐Catalyzed Enantioselective Hydroboration of Acyclic and Exocyclic 1,1‐Disubstituted Aryl Alkenes.
Authors: Corberan Rosa , Mszar Nicholas W. , Hoveyda Amir H.
Published: November 2011

New chiral bidentate N‐heterocyclic carbene—copper complexes (I) promote the enantioselective hydroboration of acyclic alkenes (II)/(V) and exocyclic 1,1‐disubstituted alkenes (VII).
ChemInform Abstract: Modifications to the Vilsmeier—Haack Formylation of 1,4‐Dimethylcarbazole and Its Application to the Synthesis of Ellipticines.
Authors: Deane Fiona M. , Miller Charlotte M. , Maguire Anita R. , McCarthy Florence O.
Published: November 2011

The improved synthesis of the compounds (III), (IX), and (XIV), which are key intermediates in the synthesis of ellipticines (VII) and its derivatives, e.g. (XII), is presented.
ChemInform Abstract: Gold α‐Oxo Carbenoids in Catalysis: Catalytic Oxygen‐Atom Transfer to Alkynes
Authors: Xiao Jian , Li Xingwei
Published: November 2011

Review: ca. 140 refs.
ChemInform Abstract: Cyclobutanes in Catalysis
Authors: Seiser Tobias , Saget Tanguy , Tran Duc N. , Cramer Nicolai
Published: November 2011

Review: ca. 100 refs.
ChemInform Abstract: Organocatalytic Hydroacylation of Unactivated Alkenes
Authors: DiRocco Daniel A. , Rovis Tomislav
Published: November 2011

Review: 22 refs.
ChemInform Abstract: Gold for C—C Coupling Reactions: A Swiss‐Army‐Knife Catalyst?
Authors: Wegner Hermann A. , Auzias Mathieu
Published: November 2011

Review: ca. 70 refs.
ChemInform Abstract: Efficient Covalent Functionalization of Carbon Nanotubes: The Use of “Click Chemistry”.
Authors: Clave Guillaume , Campidelli Stephane
Published: November 2011

Review: 91 refs.
ChemInform Abstract: Rizatriptan (Maxalt): A 5‐HT1D Receptor Agonist
Authors: Chen Cheng‐yi
Published: November 2011

Review: 25 refs.
ChemInform Abstract: More Than Just Sweet — Sugar‐Derived Stereodifferentiating Agents for Asymmetric Synthesis
Authors: Lehnert Tobias , Oezueduru Guelsuem , Grugel Holger , Albrecht Fabian , Telligmann Susanne M. , Boysen Mike M. K.
Published: November 2011

Review: about 150 refs.
ChemInform Abstract: Synthesis of N‐Substituted 1,2,4‐Triazoles. A Review
Authors: Holm Stefanie C. , Straub Bernd F.
Published: November 2011

Review: 164 refs.
ChemInform Abstract: Transformation of Carbon Dioxide with Homogeneous Transition‐Metal Catalysts: A Molecular Solution to a Global Challenge?
Authors: Cokoja Mirza , Bruckmeier Christian , Rieger Bernhard , Herrmann Wolfgang A. , Kuehn Fritz E.
Published: November 2011

Review: 317 refs.
ChemInform Abstract: Amino Acids and Peptides
Authors: Hu Chang‐Qi , Xu Jie‐Cheng
Published: November 2011

Review: 48 refs.
ChemInform Abstract: Large‐Scale Quantum Chemical Calculation for Drug Discovery
Authors: Kitaura Kazuo
Published: November 2011

Review: 17 refs.
ChemInform Abstract: Recent Progress in the Theoretical Studies of Structure, Function, and Reaction of Biological Molecules
Authors: Hirao Hajime , Morokuma Keiji
Published: November 2011

Review: 44 refs.
Quaternary Ammonium Salts and Their Antimicrobial Potential: Targets or Nonspecific Interactions?
Authors: Tischer Maximilian , Pradel Gabriele , Ohlsen Knut , Holzgrabe Ulrike
Published: November 2011

For more than 50 years dequalinium chloride has been used successfully as an antiseptic drug and disinfectant, particularly for clinical purposes. Given the success of dequalinium chloride, several series of mono‐ and bisquaternary ammonium compounds have been designed and reported to have improved antimicrobial activity. Furthermore, many of them exhibit high activity against mycobacteria and protozoa, especially against plasmodia. This review discusses the structure–activity relationships and the modes of action of the various series of (bis)quaternary ammonium compounds.
Detecting ketamine in beverage residues: Application in date rape detection
Authors: Albright Jessica A. , Stevens Sarah A. , Beussman Douglas J.
Published: November 2011

Ketamine can be used to facilitate date‐rape when unknowingly spiked into a victim's beverage. If a biological sample is not available from the victim, the beverage container might be the only remaining source of forensic evidence. We present a rapid, simple analysis method for the detection of ketamine in wet or dry beverage residues based on liquid chromatography‐mass spectrometry (LC‐MS). Wet residues consist of the final few drops (<1 ml) in a container while dry residues are the remains once all liquid has evaporated. By using LC‐MS, which readily handles aqueous samples, often no derivatization or sample extraction is needed, thus reducing analysis time and lab technician involvement. Tandem mass spectrometry (MS/MS) provides an enhancement in both selectivity and sensitivity. We have studied a range of beverages and determined limits of detection between 1.2 × 10–3 and 1.3 × 10–4 mg/ml, compared to 0.21–0.85 mg/ml used in most date‐rape scenarios. This paper represents the first published report of using LC‐MS/MS for the analysis of beverage residues for the presence of a date‐rape drug. This method could replace the current gas chromatography‐mass spectrometry (GC‐MS) methods and provide a faster, more selective method for the analysis of date‐rape drugs, requiring virtually no sample preparation. Copyright © 2011 John Wiley & Sons, Ltd.
Historical perspective and modern applications of Attenuated Total Reflectance – Fourier Transform Infrared Spectroscopy (ATR‐FTIR)
Authors: Blum Marc‐Michael , John Harald
Published: November 2011

Vibrational spectroscopy has a long history as an important spectroscopic method in chemical and pharmaceutical analysis. Instrumentation for infrared (IR) spectroscopy was revolutionized by the introduction of Fourier Transform Infrared (FTIR) spectrometers. In addition, easier sampling combined with better sample‐to‐sample reproducibility and user‐to‐user spectral variation became available with attenuated total reflectance (ATR) probes and their application for in situ IR spectroscopy. These innovations allow many new applications in chemical and pharmaceutical analysis, such as the use of IR spectroscopy in Process Analytical Chemistry (PAC), the quantitation of drugs in complex matrix formulations, the analysis of protein binding and function and in combination with IR microscopy to the emergence of IR imaging technologies. The use of ATR‐FTIR instruments in forensics and first response to ‘white powder’ incidents is also discussed. A short overview is given in this perspective article with the aim to renew and intensify interest in IR spectroscopy. Copyright © 2011 John Wiley & Sons, Ltd.
Lessons from the Application of Decision‐support Tools in Participatory Management of the New Forest National Park, UK
Authors: Edwards Victoria M. , Smith Simon
Published: November 2011

This paper reports on participatory processes using agent‐based simulation models which were employed in the New Forest National Park, UK, to facilitate greater appreciation of recreational impact on wildlife and in turn support proposed revisions in management. The models helped to foster a greater understanding of the need for visitor management, but some stakeholders seemed intent on discrediting them and opposing any changes to recreational management. The inherent complexity and lack of user‐friendly application of the models meant that use of them was compromised. Opportunities should be sought to increase stakeholder involvement in the long‐term collection of data and validation of models, and to embed participatory processes in existing decision‐making institutions. Overall, the decision support tools detracted attention from opportunities for researching social learning: tools need to be part of a well‐run deliberative learning process that addresses stakeholder representation and power relationships, knowledge validation, social learning and improved transparency. Copyright © 2011 John Wiley & Sons, Ltd and ERP Environment.
Application of Glassy Carbon Electrode Modified with a Bilayer of Multiwalled Carbon Nanotube and Polypyrrole Doped with Nitrazine Yellow for Voltammetric Determination of Naltrexone
Authors: Shahrokhian Saeed , Kamalzadeh Zahra , Saberi Reyhaneh‐Sadat
Published: November 2011

A new sensitive electrochemical sensor was fabricated based on a layer by layer process. In this process the glassy carbon electrode (GCE) is first coated by a thin film of multiwalled carbon nanotubes (MWCNTs). In the next step, the electropolymerization of pyrrole in the presence of Nitrazine Yellow (NY) as a dopant anion is performed on the surface of the MWCNTs precoated electrode. The electrochemical response characteristics of the modified electrode toward naltrexone (NTX) were studied by means of linear sweep voltammetry (LSV). A remarkable increase (∼19 times) was observed in the anodic peak current of NTX on the surface of the modified electrode relative to the bare GCE. The effects of experimental parameters on the electrode response such as, drop size of the cast MWCNTs suspension, pH of the supporting electrolyte, accumulation conditions and the number of cycles in the electropolymerization process were investigated. Under the optimum conditions, the modified electrode showed a wide linear response to the concentration of NTX in the range of 4.0×10−8–1×10−5 mol L−1 with a detection limit of 12 nmol L−1. The prepared sensor exhibited high sensitivity, stability and good reproducibility for the determination of NTX. This sensor was successfully applied for the accurate determination of trace amounts of NTX in pharmaceutical and clinical preparations.
Enhanced sensitivity of LC‐MS analysis of permethylated N‐glycans through online purification
Authors: Desantos‐Garcia Janie L. , Khalil Sarah I. , Hussein Ahmed , Hu Yunli , Mechref Yehia
Published: November 2011

Aberrant glycosylation of proteins and lipids has been implicated in many human diseases, thus prompting the need for reliable analytical methods that permit dependable quantification of glycans originating from biological specimens. MS of permethylated glycans is currently employed to monitor disease‐related aberrant glycosylation of proteins and lipids. However, enhancing the sensitivity of this type of analysis is still needed. Here, analysis of permethylated glycans at enhanced sensitivity is attained through miniaturized solid‐phase permethylation and online solid‐phase purification. Solid‐phase permethylation method was miniaturized by reducing the amount of sodium hydroxide beads (one‐third the original amount) packed in microspin columns. The efficiency of glycan permethylation was not adversely affected by this reduction. Online solid‐phase purification of permethylated N‐glycans derived from model glycoproteins, such as fetuin, α‐1 acid glycoprotein and ribonuclease B, offered more sensitive and reproducible results than offline liquid–liquid and solid‐phase extractions. Online solid‐phase purification method described here permitted a 75% increase in signal intensities of permethylated glycans relative to offline purification methods. This is mainly due to the minimized sample handling associated with an online cleaning procedure. The efficiency and utility of online solid‐phase purification was also demonstrated here for N‐glycans derived from human blood serum. Online solid‐phase purification permitted the detection of 73 N‐glycan structures, while only 63 glycan structures were detected in the case of samples purified through liquid–liquid extraction. The intensities of the 63 structures that were detected in both cases were 75% higher for samples that were purified through the online method.
Decagonal Quasicrystals and Approximants: Two‐Dimensional or Three‐Dimensional Solids?
Authors: Dolinšek Janez , Smontara Ana
Published: November 2011

Crystallographic structures of decagonal quasicrystals (d‐QCs) are traditionally described as a periodic stacking of atomic planes with quasiperiodic in‐plane atomic order, so that d‐QCs are considered to be two‐dimensional (2D) quasicrystals, whereas they are periodic crystals in the third dimension. Similar stacked‐layer structures are observed also in the periodic decagonal approximant phases. In this review paper, we consider the dimensionality of the chemical bonding network in the d‐QCs and their approximants on the basis of electrical resistivity. By comparing the anisotropic resistivity along the stacking‐ and the in‐plane directions of a series of decagonal approximants with different numbers of atomic layers within one periodicity unit (the two‐layer Y‐Al‐Co‐Ni, the four‐layer o‐Al13Co4, Al13Fe4 and Al13(Fe,Ni)4, and the six‐layer Al4(Cr,Fe) and T‐Al3(Mn,Fe)) and of a two‐layer d‐Al‐Co‐Ni decagonal quasicrystal, we show that universally, the stacking direction perpendicular to the atomic planes is always the most conducting one. Since the in‐plane electrical resistivities are of the same order of magnitude as the resistivity along the stacking direction, this confirms the 3D character of the investigated solids. The stacked‐layer description in terms of 2D atomic planes should therefore be regarded as a convenient geometrical approach to describe the complex structures of the d‐QCs and their approximants, whereas their physical properties are those of true 3D solids.
REVERSE REGRESSIONS AND LONG‐HORIZON FORECASTING
Authors: Wei Min , Wright Jonathan H.
Published: November 2011

Long‐horizon predictive regressions in finance pose formidable econometric problems when estimated using available sample sizes. Hodrick in 1992 proposed a remedy that is based on running a reverse regression of short‐horizon returns on the long‐run mean of the predictor. Unfortunately, this only allows the null of no predictability to be tested, and assumes stationary regressors. In this paper, we revisit long‐horizon forecasting from reverse regressions, and argue that reverse regression methods avoid serious size distortions in long‐horizon predictive regressions, even when there is some predictability and/or near unit roots. Meanwhile, the reverse regression methodology has the practical advantage of being easily applicable when there are many predictors. We apply these methods to forecasting excess bond returns using the term structure of forward rates, and find that there is indeed some return forecastability. However, confidence intervals for the coefficients of the predictive regressions are about twice as wide as those obtained with the conventional approach to inference. We also include an application to forecasting excess stock returns. Copyright © 2011 John Wiley & Sons, Ltd.
Biomimetic chitosan–calcium phosphate composites with potential applications as bone substitutes: Preparation and characterization
Authors: Tanase Constantin E. , Popa Marcel I. , Verestiuc Liliana
Published: November 2011

A novel biomimetic technique for obtaining chitosan—calcium phosphates (Cs‐CP) scaffolds are presented: calcium phosphates are precipitated from its precursors, CaCl2 and NaH2PO4 on the Cs matrix, under physiological conditions (human body temperature and body fluid pH; 37oC and pH = 7.2, respectively). Materials composition and structure have been confirmed by various techniques: elemental analysis, Fourier transform infrared spectroscopy (FTIR), X‐ray diffraction (XRD), energy dispersive X‐ray spectroscopy (EDX), and scanning electron microscopy (SEM). FTIR and SEM data have shown the arrangement of the calcium phosphates‐hydroxyapatite (CP‐Hap) onto Cs matrix. In this case the polymer is acting as glue, bonding the calcium phosphates crystals. Behavior in biological simulated fluids (phosphate buffer solution—PBS and PBS—albumin) revealed an important contribution of the chelation between
$ - {\rm{NH}}_3^ + $
and Ca2+ on the scaffold interaction with aqueous mediums; increased quantities of chitosan in composites permit the interaction with human albumin and improve the retention of fluid. The composites are slightly degraded by the lysozyme which facilitates an in vivo degradation control of bone substitutes. Modulus of elasticity is strongly dependent of the ratio chitosan/calcium phosphates and recommends the obtained biomimetic composites as promising materials for a prospective bone application. © 2011 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2012.
Treatment of various secondary lymphedemas by microsurgical lymph vessel transplantation
Authors: Felmerer Gunther , Sattler Thorsten , Lohrmann Christian , Tobbia Dalia
Published: November 2011

Chronic lymphedema is a debilitating complication of cancer diagnosis and therapy and poses many challenges for health care professionals. It remains a poorly understood condition that has the potential to occur after any intervention affecting lymph node drainage mechanism. Microsurgical lymph vessel transplantation is increasingly recognized as a promising method for bypassing the obstructed lymph pathways and promoting long‐term reduction of edema in the affected limb. A detailed review of 14 patients with postoperative lymphedema treated with autologous lymph vessel transplantation between October 2005 and November 2009 was performed. In this report, the authors gave an account of their experience in utilizing this operative method to alleviate secondary lymphedema including upper limb, lower limb, genital, and facial edemas. Lymph vessel transplantation enhanced lymphatic drainage in patients with secondary lymphedema. In the upper and lower extremities, three patients had completed symptomatic recovery and another nine patients achieved reasonable reduction of lymphedema, four of these needed no further lymph drainage or compression garments and the remaining maintained their improvement with further decongestive therapy with or without compression garments. The patients with facial and genital edemas also experienced significant symptomatic improvement. The authors were able to establish long‐term patency of the lymph vessel anastomosis by magnetic resonance lymphangiography. © 2011 Wiley Periodicals, Inc. Microsurgery, 2012.
The psychometric properties of the K10 and K6 scales in screening for mood and anxiety disorders in the South African Stress and Health study
Authors: Andersen L. S. , Grimsrud A. , Myer L. , Williams D. R. , Stein D. J. , Seedat S.
Published: November 2011

Emerging research has provided support for the use of the Kessler Psychological Distress Scales in developing countries; however, this research has yet to be extended to southern Africa. This study sought to evaluate the performance of the Kessler scales in screening for depression and anxiety disorders in the South African population. The scales along with the Composite International Diagnostic Interview (CIDI) were included in the South African Stress and Health study, a nationally representative household survey. The K10/K6 demonstrated moderate discriminating ability in detecting depression and anxiety disorders in the general population; evidenced by area under the receiver operating curves of 0.73 and 0.72 respectively. However, both scales failed to meet our acceptability criteria of high sensitivity and high positive predictive value. Examinations of differences in responding by race/ethnicity revealed that the K10/K6 [Kessler Psychological Distress Scale 10‐item (K10) and the abbreviated six‐item (K6)] had significantly lower discriminating ability with respect to depression and anxiety disorders among the Black group (0.71) than among the combined minority race/ethnic groups of White, Colored, and Indian/Asian (0.78; p = 0.016). The difference in time period assessed on the K10/K6 (past 30 days) versus the CIDI (past 12 months) was a notable limitation of this study. Additional validation studies using clinician diagnostic instruments are recommended. Copyright © 2011 John Wiley & Sons, Ltd.