bluuebunny/crossref_metadata_2025 huggingface dataset:
Innovation Centers in Health Care Delivery Systems: Structures for Success (Preprint)
Authors: Bhattacharyya Onil , Shapiro Justin , Schneider Eric C
Published: October 2021

UNSTRUCTURED

The need to support innovation in health care delivery was prompted by payment reforms and access to digital tools and has been accelerated by the shift to virtual care as part of the COVID-19 pandemic response. Prior to the pandemic, a growing number of health systems set up innovation centers to focus on creating new services and exploring new business models relevant to value-based care. This is distinct from process improvement or implementation science, and often needs a different set of incentives to succeed within a large organization. We used a national survey to identify a diverse sample of innovation centers, and interviewed leaders to describe their aims, organizational structures, and activities. They all aim to improve patient outcomes and experience while reducing costs, but their strategic focus may differ. The centers also vary in their reporting structure, how they build internal capacity, and how they measure success. We highlight the range of strategies through examples of projects that improve quality, reduce costs, and generate new revenue. While the optimal forms and impact of innovation centers are still emerging, the fiscal pressures and the rapid uptake of digital technologies present opportunities for the redesign of health services in the postpandemic era. The experiences of these centers illustrate a set of approaches to increase any organization’s capacity for innovation.
Wisdom of the Experts versus Wisdom of the Crowd in Hospital Quality Ratings: Cross-Sectional Analyses of Google Ratings (Preprint)
Authors: Ramasubramanian Hari , Joshi Satish , Krishnan Ranjani
Published: October 2021

BACKGROUND

Popular online portals provide free and convenient access to user-generated quality reviews. Centers for Medicare and Medicaid Services (CMS) also provide patients with Hospital Compare Star Ratings (HCSR), a single public measure of hospital quality aggregating multiple quality dimensions. Consumers often use crowdsourced hospital ratings on platforms such as Google to select hospitals, but it is unknown if these ratings reflect a comprehensive measure of clinical quality.

OBJECTIVE

We analyze if Google online quality ratings, which reflect the wisdom of the crowd, are associated with HCSR, which reflect the wisdom of the experts. CMS revised the methodology of assigning star ratings to hospitals. Therefore, we analyze these associations before and after the 2021 revisions of the CMS rating system.

METHODS

We extracted Google ratings using Application Programming Interface (API) in June 2020. The HCSR data of April 2020 (before the revision of HCSR methodology) and April 2021 (after the revision of HCSR methodology) were obtained from CMS’ Hospital Compare (HC) website. We also extracted scores for the individual components of hospital quality for each of the hospitals in our sample using the code provided by HC. Fractional Response Model (FRM) was used to estimate the association between Google Ratings and HCSR and individual components of quality.

RESULTS

Results indicate that Google ratings are statistically associated with HCSR (P<.001) after controlling for hospital level effects. A one star improvement in CMS ratings before the change in methodology (after the change in methodology) is expected to increase the Google ratings by 0.145 (0.135) on average (95% CI 0.127- 0.163; P<.001, 95% CI 0.116-0.153; P<.001). The analyses with individual components of hospital quality reveal that Google ratings are not associated with components of HCSR that require medical expertise such as ‘Safety of care’ or ‘Readmissions’. The revised CMS rating system ameliorates previous partial inconsistencies in association between Google ratings and component scores of HCSR.

CONCLUSIONS

Overall, crowd sourced Google hospital ratings are informative about expert CMS hospital quality ratings and several individual quality components that are easier for patients to evaluate. Therefore, hospitals should not expect improvements in quality metrics that require expertise to assess such as safety of care and readmission to result in improved Google star ratings. Hospitals can benefit from using crowd-sourced ratings as timely, easily available, and dynamic indicators of their quality performance.
Appeal of editor-in-chief
Authors: Sirenko U.
Published: October 2021

No abstract
The structure of the drug therapy prescription to cardiac patients during the primary care: the lessons of the OZIRKA study
Authors: Torbas O.O. , Kushnir S.M. , Rekovets O.L. , Sirenko Yu.M.
Published: October 2021

The structure of prescriptions of cardiac drugs by the primary care physicians has remained unknown for a long time. We decided to use the data of the OZIRKA study, which aimed to investigate the effect of Ozalex (rosuvastatin) on lipid and cholesterol levels in patients with lipid metabolism disorders and hypercholesterolemia, and to assess the structure of prescriptions in real clinical practice, as well as the effectiveness of cardiovascular risk factors monitoring. We sincerely hope that the data we have obtained will optimize the treatment plan for primary care patients, improve their prognosis and survival, and provide the practitioner with evidence of the safety and efficacy of rosuvastatin that can be transferred to routine clinical practice.
On the problem of the relationship between arterial hypertension and coronavirus disease (COVID-19): literature review
Authors: Koval S.M. , Mysnychenko O.V. , Penkova M.Yu.
Published: October 2021

The literature review is devoted to the problem of the relationship between arterial hypertension and coronavirus disease (CVD; COVID-19), which has attracted attention from the very beginning of the pandemic of this infectious disease. The literature data, despite certain disagreements, indicate a higher incidence of CVD (COVID-19) among hypertensive patients, especially the elderly and patients with comorbid cardiovascular diseases, obesity, and diabetes mellitus. Besides, it has been shown that in these patients, CVD (COVID-19) has a more severe course. In this regard, these categories of patients need to provide effective treatment and prophylactic care and create conditions for the prevention of CVD (COVID-19) infection based on the modern European standards.
Astaxanthin-Producing Microalgae Identification Using 18S rRNA : Isolates from Bangkalan Mangrove Waters and Sowan Tuban Northern Waters, East Java, Indonesia
Authors: Ermavitalini Dini , Rukhmana Siska Yulia , Meidina Thalita , Baskoro Leonardo Pascalis Dimas Cahyo , Saputro Triono Bagus , Ni’matuzahroh Ni’matuzahroh , Purnobasuki Hery
Published: October 2021

Microalgae are a group of micro-sized photosynthetic organisms that range from prokaryotic cyanobacteria to eukaryotic algae. Microalgae are widely used as a source  of natural food, cosmetic ingredients, food ingredients, and a source of pigments. This study aims to identify species of four microalgae isolates named B1, B2, B3, and S2 from Bangkalan Mangrove Waters and Sowan Tuban Northern Waters, and to determine their astaxanthin pigment concentration under 1 M NaCl. Species identification was carried out through a molecular approach by utilization of an 18S rRNA gene marker. A quantitative test of astaxanthin concentration was carried out by spectrophotometric analysis. Molecular identification results show that isolates B1 and B3 are closely related to Chlorella sp., while isolates B2 and S2  are closely related to Picochlorum maculatum. Moreover, under salinity stress condition of 1 M NaCl shown a significant decrement of astaxanthin production compared to the control treatment. At 1 M NaCl, the astaxanthin content of isolate B1 was 4x10-5 mgL-1, isolate B2 was 2x10-5 mgL-1, isolate B3 was 1x10-5 mgL-1, and isolate S2 was 6x10-6 mgL-1. All in all, isolate S2 has the highest astaxanthin among the other isolates at normal conditions, while under salt stress regime, isolate B1 shown to be the best source for astaxanthin.
Effect of Iron Toxicity on the Growth of Calliandra calothyrsus and Leucaena leucocephala Seedlings
Authors: Salim Mohammad Agus , Setyaningsih Luluk , Wahyudi Imam , Budi R Sri Wilarso
Published: October 2021

Iron (Fe) is a micro essential needed by plants in small amounts and can be toxic when available in large quantities. This study aimed to evaluate how Fe exposure affects the growth of C. callothyrsus and L. leucocephala seedlings. This study used a completely randomized design with factorial, where the first factor consisted of two levels of seedlings (C. calothyrsus and L. leucocephala), and the second factor consisted of Fe concentration which consisted of 8 levels (0, 0.25, 0.5, 0.75, 1, 1.25, 1.5, and 1.75 mM). The results showed that treatment of seedlings species and concentration of Fe was able to significantly affect the growth parameters (height, root length, root dry weight, shoots, and plant dry weight) of seedlings. The control treatment (without Fe) showed the highest growth response compared to those treated with Fe exposure and an increase in Fe concentration was able to reduce all growth parameters in both seedlings. The 0.5 mM Fe concentration reduced all growth parameters of C. calothyrsus drastically, while in L. leucocephala, the Fe 0.75 concentration was able to decrease all growth parameters drastically. The tolerance index of both seedlings decreased with increasing Fe concentration. The rate of photosynthesis did not show a significant difference between treatments, meanwhile, it had a significant effect on chlorophyll affect chlorophyll (a, b, and total chlorophyll) and carotenoid content. The highest Fe content in C. calothyrsus seedlings was at a concentration of 1.5 mM (4.40%), while in L. leucocephala seedlings, the highest Fe content was at 1.7 mM (2.87%).
D NUMBERS – FUCOM – FUZZY RAFSI MODEL FOR SELECTING THE GROUP OF CONSTRUCTION MACHINES FOR ENABLING MOBILITY
Authors: Božanić Darko , Milić Aleksandar , Tešić Duško , Salabun Wojciech , Pamučar Dragan
Published: October 2021

The paper presents a hybrid model for decision-making support based on D numbers, the FUCOM method and fuzzified RAFSI method, used for solving the selection of the group of construction machines for enabling mobility. By applying D numbers, the input parameters for the calculation of the weight coefficients of the criteria were provided. The calculation of the weight coefficients of the criteria was performed using the FUCOM method. The best alternative was selected using the fuzzified method, which was conditioned by the specificity of the issue so that in this case, the selection of the best alternative was made using the fuzzified RAFSI method.
AN EXTENDED SINGLE-VALUED NEUTROSOPHIC AHP AND MULTIMOORA METHOD TO EVALUATE THE OPTIMAL TRAINING AIRCRAFT FOR FLIGHT TRAINING ORGANIZATIONS
Authors: Karamaşa Çağlar , Karabasevic Darjan , Stanujkic Dragisa , Kookhdan Alireza Rezanezhad , Mishra Arunodaya Raj , Ertürk Mehmet
Published: October 2021

Aircraft’s training is crucial for a flight training organization (FTO). Therefore, an important decision that these organizations should wisely consider the choice of aircraft to be bought among many alternatives. The criteria for evaluating the optimal training aircraft for FTOs are collected based on the survey approach. Single valued neutrosophic sets (SVNS) have the degree of truth, indeterminacy, and falsity membership functions and, as a special case, neutrosophic sets (NS) deal with inconsistent environments. In this regard, this study has extended a single-valued neutrosophic analytic hierarchy process (AHP) based on multi-objective optimization on the basis of ratio analysis plus a full multiplicative form (MULTIMOORA) to rank the training aircraft as the alternatives. Moreover, a sensitivity analysis is performed to demonstrate the stability of the developed method. Finally, a comparison between the results of the developed approach and the existing approaches for validating the developed approach is discussed. This analysis shows that the proposed approach is efficient and with the other methods.
Estándar de metadatos para la interoperabilidad jurídica de repositorios universitarios
Authors: Chávez Méndez Ariana , Méndez Franco Ana Laura , Sáenz González Rubén , López Coca Karina Anahi , Pérez Ortiz Tila María
Published: October 2021

La presente publicación, el “Estándar de metadatos para la interoperabilidad jurídica de repositorios universitarios”, tiene como objetivo presentar, comunicar y difundir, de forma consistente e íntegra, los procesos para lograr la búsqueda, recuperación, uso, preservación, interoperabilidad y acceso abierto de los contenidos digitales de los repositorios universitarios.
Una aproximación a la temporalidad absoluta del arte rupestre pictográfico de Puerto Rico
Authors: Rodriguez Ramos Reniel , Acosta-Colón Angel A. , Pérez Reyes Roberto
Published: October 2021

Puerto Rico cuenta con un amplio y diverso registro de arte rupestre. Aunque se han realizado importantes contribuciones al estudio de este tipo de manifestación cultural, al presente se tiene información muy limitada sobre su cronología. Sobre la base de 61 fechados obtenidos de los pigmentos orgánicos empleados en la producción de pictografías en diversos contextos arqueológicos de Puerto Rico, se hace una aproximación inicial a la temporalidad absoluta del arte rupestre pintado en la isla. Los resultados obtenidos presentan un panorama amplio del uso de este tipo de manifestación en sus diversos periodos de ocupación, con fechas iniciales directas que se remontan entre cal. 740 y 400 a.C., representando esta la primera evidencia concreta de arte rupestre asociado con los primeros pobladores de la isla. De igual forma, se logró documentar la producción de este tipo de arte rupestre posiblemente asociado a la tradición Saladoide del suroeste de la isla, con fechas entre cal. 220 y 380 d.C. La producción de imágenes pintadas se incrementa en cantidad y diversidad después del 700 d.C., comenzando con la grafía de elementos antropomorfos y, posteriormente, de imágenes zoomorfas, las cuales se comienzan a registrar de forma marcada después del 1000 d.C. La producción de pictografías de humanos y animales, así como de otros elementos foráneos, se extiende al periodo colonial de la isla, lo que demuestra continuidades en el uso de las cuevas como contextos de registro tras la llegada de los invasores europeos al territorio de la isla.
Representaciones ofídicas en el arte rupestre de Alva (Bongará, Amazonas-Perú): el culto al agua y las redes de interacción interregional durante el Formativo
Authors: Villar Quintana Anthony Alex
Published: October 2021

El estudio de las pinturas rupestres plasmadas en un abrigo rocoso de la zona de Alva (distrito de Shipasbamba, provincia de Bongará, Amazonas-Perú) tuvo como objetivo determinar la función de ese abrigo durante el periodo Formativo, así como sus implicaciones en la formación del corpus iconográfico y su inserción en las redes de interacción interregional durante el referido periodo. El análisis iconográfico (compositivo y comparativo) de esas representaciones y la relación con su entorno nos permite plantear que durante el Formativo este abrigo rocoso funcionó como un santuario dedicado a las serpientes, relacionado a su vez con actividades de culto al agua, en una ruta que conectaba la Amazonia con los Andes.
World heritage: On the 200th anniversary of Dostoevsky’s birth
Authors: Galtsova Elena D.
Published: October 2021

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The Polyphony of the Silent: The Specifics of Dostoevsky’s Philosophical Discourse
Authors: Krinitsyn Alexandr B.
Published: October 2021

The article describes the phenomenon of silence in Dostoevskys later prose. Philosophical, plot-forming and psychological aspects of silence are looked at. A confessional type of monologue is defined as a discursive genre, with specific roles of the speaker and his silent listeners, whose predominance in Dostoevskys prose lets the author of the article adjust the notion of polyphony and dialogue within the context of Dostoevskys poetics. The conventionality of the other in the confessional type of monologue is proved by the absence of the completing functions in listeners. In most cases Dostoevskys later works retain some rudimental forms of frantic dialogue while the role of specific monologue discourse, caused and conditioned by silence, is increasing. By semantics and function types of silence in Dostoevsky fall into three groups: 1) the underground silence as expression of human disunity in the epoch of universal solitude; 2) role silence of listeners in the discursive genre of confessional monologue; 3) sacred silence of Christ indicating transition to a new higher level of communication
How to Translate Dostoevsky from French into French? “L’homme de la nature et de la vérité” and “animaux domestiques” in Notes from Underground
Authors: Galtsova Elena D.
Published: October 2021

The article deals with the use of French expressions in the text of F. Dostoevskys Notes from Underground . On the one hand, various semantic nuances of bilingualism and associations with some cultural contexts are revealed. On the other hand, translations and explanations of these expressions given by translators of the novella are analyzed. While lhomme de lа nature et de la vrit is a citation which shows that it is impossible to render French character into Russian culture, aux animaux domestiques carries this idea to the point of absurdity.
Ressentimento e Eterno Retorno na série Dark
Authors: Silva Júnior Stamberg José da , Von Zuben Marcos de Camargo
Published: October 2021

Este artigo investiga, utilizando uma abordagem exploratória, o modo como os conceitos de ressentimento e eterno retorno, propostos por Nietzsche, estão presentes na primeira temporada da série original da Netflix, a produção Dark (2017). Analisa-se a relação entre as ideias do filósofo alemão e a narrativa de ficção seriada germânica a partir de uma chave imagético-discursiva que visa a concatenar os pressupostos de Nietzsche ao enredo e argumento da série. Os resultados apontam para as ideias de eterno retorno e ressentimento como alguns dos possíveis leitmotivs de Dark.
Raúl Fuentes Navarro: contribuições ao campo acadêmico da comunicação
Authors: Souza Antonio Carlos
Published: October 2021

Raúl Fuentes Navarro, professor e pesquisador mexicano, tem se dedicado a investigar a pesquisa da comunicação e a profissionalização da área, na América Latina, de modo geral, e no México, de modo específico. Por causa desse interesse, suas investigações estão voltadas para Teorias da Comunicação, Epistemologias da Comunicação e Metodologias de Pesquisa em Comunicação. As décadas de dedicação à área levaram à produção de 26 livros, 85 capítulos e mais de 120 artigos em revistas especializadas. Nesta entrevista, Fuentes Navarro compartilha algumas impressões sobre os desafios para estudar a comunicação em países latino-americanos.
Acolhimento e resistência a correções de fake news na pandemia: a experiência do robô Fátima, da agência Aos Fatos, no Twitter
Authors: Paganotti Ivan
Published: October 2021

Agências de checagem de fatos enfrentam o desafio de fazer com que suas verificações alcancem públicos que desconhecem, desconfiam ou hostilizam seus métodos de verificação. Redes sociais, espaço em que proliferam notícias falsas, podem ser um espaço para ampliar o público dessas agências. O artigo avalia a experiência da conta automatizada no Twitter criada pela agência Aos Fatos para identificar e interagir com usuários dessa rede social que publicam informações falsas. O robô apelidado de “Fátima” varre o Twitter para identificar postagens com links que já foram refutados pela agência de verificação, e responde aos usuários indicando o erro e sua correção. Esta pesquisa procura avaliar quais notícias falsas foram mais frequentes durante a pandemia em 2020, e de que forma os usuários interagiram em resposta a essas correções.
Negacionismo em textos acadêmicos no Portal de Periódicos Capes
Authors: Zanotti Carlos Alberto , Carvalho Marcello Mattos de
Published: October 2021

Este trabalho parte de uma discussão sobre o crescente uso da expressão negacionismo – na imprensa ou em debates acadêmicos publicados na mídia – para investigar a produção científica, em língua portuguesa, sobre o uso do termo em textos indexados no Portal de Periódicos da Capes. Com origem no desejo de negar uma verdade para aplacar aflições individuais, a expressão nasceu na psicanálise freudiana, e hoje designa conduta de caráter coletivo. O estudo aqui proposto adota pesquisa bibliográfica, estratégias bibliométricas e técnicas de análise de conteúdo visando apurar recortes e conceitos acolhidos nos estudos recuperados daquele banco de dados. O resultado aponta a existência de apenas 6 trabalhos indexados no Portal, todos publicados entre os anos de 2009 e 2020.
Carnavalização bakhtiniana e o arquétipo bobo da corte na produção de sentido nas mídias
Authors: Contani Miguel Luiz , Todeschini Vieira Nattalia , Gomes de Oliveira Esther
Published: October 2021

A noção de arquétipo, muito utilizada na publicidade, denomina O Bobo da Corte quando aplica a comédia e o humor em sua linguagem, como estímulo à absorção do caos do mundo de forma extrovertida. Contém elementos com que Mikhail Bakhtin estabelece um dos pilares da Teoria da Carnavalização: o riso medieval. Esses conceitos, embora criados em épocas distantes, podem ser observados na mídia contemporânea com o mesmo propósito. O presente trabalho analisa o diálogo entre o arquétipo Bobo da Corte e o riso medieval bakhtiniano nas emissões efetuadas pela produtora Porta dos Fundos.
O “espetáculo da vida vivida” e a história como vir a ser
Authors: Barbosa Marialva
Published: October 2021

Este ensaio tem por objetivo refletir sobre o cotidiano enredado nas afetações do presente, a partir da articulação entre o cotidiano como espetáculo vivido e a história na dimensão do que poderia ter sido e não como o realizado do passado. Trata-se de uma história do provável em que a dimensão da vida vivida permite articular outros caminhos de possibilidades.
Faktor-Faktor yang Berhubungan dengan Perilaku Cuci Tangan Pakai Sabun (CTPS) pada Mahasiswa Universitas Jambi Selama Pandemi COVID-19
Authors: Sianipar Esra , Ridwan M. , Ibnu Ismi Nurwaqiah , Guspianto Guspianto , Reskiaddin La Ode
Published: October 2021

COVID-19 merupakan penyakit menular yang cepat menyebar. Di Indonesia terdapat jumlah kasus terkonfirmasi positif COVID-19 1.863.031 sedangkan di Provinsi Jambi 108 kasus per tanggal 07 Juni 2021. Cuci Tangan Pakai Sabun dapat mencegah penularan COVID-19 di kampus. Penelitian ini bertujuan untuk menganalisis faktor-faktor yang berhubungan dengan perilaku cuci tangan pakai sabun (CTPS) pada mahasiswa Universitas Jambi selama pandemi COVID-19. Penelitian ini menggunakan pendekatan kuantitatif dengan desain studi Cross-Sectional. Jumlah Sampel yang digunakan sebanyak 106 mahasiswa yang dipilih menggunakan teknik Multistage Sampling. Berdasarkan hasil uji statistik, hubungan pengetahuan dan sarana prasarana dengan perilaku CTPS masing-masing memiliki nilai p-value sebesar 0,191 dan 0,804 (p > 0,05) sedangkan untuk hubungan sikap dan dukungan teman sebaya dengan perilaku CTPS memiliki nilai p-value sebesar 0,030 dan 0,000 (p < 0,05). Pengetahuan dan sarana prasarana tidak memiliki hubungan yang signifikan dengan perilaku CTPS, sedangkan sikap dan dukungan teman sebaya memiliki hubungan yang signifikan dengan perilaku CTPS.Kata Kunci: Mahasiswa, Cuci Tangan Pakai Sabun (CTPS), COVID-19.
Kajian Kejadian Berat Badan Lahir Rendah di Indonesia: Analisis Data Survei Demografi dan Kesehatan Indonesia tahun 2017
Authors: Sadarang Rimawati
Published: October 2021

Kondisi Berat Badan Lahir Rendah (BBLR) berkontribusi tidak hanya pada angka kematian bayi tetapi juga pada masalah kesehatan lainnya. Penelitian ini bertujuan untuk mengetahui prevalensi BBLR dan mengidentfikasi perbedaan rata-rata BBLR di Indoensia berdasarkan usia ibu, tingkat pendidikan ibu, jenis tempat tinggal, lokasi tempat tinggal, indeks kesejahteraan, kunjungan antenatal care (ANC), dan konsumsi tablet Fe selama kehamilan. Penelitian ini menggunakan data survei Demografi dan Kesehatan Indonesia tahun 2017 dengan rancangan cross sectional study. Analisis data dilakukan terhadap wanita usia subur yang pernah melahirkan dan memiliki catatan berat badan lahir bayi pada Kartu Menuju Sehat (KMS)/ buku Kesehatan Ibu dan Anak (KIA) secara deskriptif dan analitik. Uji beda menggunakan one way anova, kruskall wallis, dan unpaired ttest dengan p-value 0,05 sebagai cut off point. Prevalensi BBLR mencapai angka 6,1%. Rata-rata berat badan lahir terendah teridentifikasi dialami oleh ibu yang berusia 15-19 tahun (1.944,0 gram), tidak pernah menamatkan minimal satu jenjang pendidikan (1.925,0 gram), tidak pernah melakukan kunjungan ANC (1.900,0 gram), dan tidak pernah mengonsumsi tablet Fe selama kehamilan (1.750,0 gram). Berdasarkan lokasi dan indeks kesejahteraan, Pulau Jawa (34,5%), wilayah perkotaan (51,5%) dan keluarga dengan indeks kesejahteraan paling rendah (29,4%) merupakan kontributor utama terhadap angka BBLR di Indonesia. Perbedaan rata-rata BBLR hanya signifikan secara statistik pada variabel tingkat pendidikan (p = 0,0279). Edukasi kepada ibu hamil terkait BBLR sangat dibutuhkan agar ibu hamil mengatahui faktor risiko BBLR yang dimiliki dan dapat melakukan pencegahan secara mandiri.Kata Kunci: Antenatal Care, Berat Badan Lahir Rendah, Faktor Risiko.
Designed ONE-FLOW System for the Synthesis of Rufinamide
Authors: Zhang Chenyue , Martino Teresa de , Bloemendal Victor , Rutjes Floris , Jin Can , Hessel Volker , Hest Jan van
Published: October 2021

A nano-compartmentalized one-solvent (ONE-FLOW) procedure was developed
for the two-step synthesis of Rufinamide, employing a combined
simulation and experimental approach. Computer-aided solvent selection
was combined with reagent/catalyst compartmentalization in a continuous
flow set-up. The synthetic route encompassed azidation of benzyl
chloride, followed by a Cu-catalyzed azide alkyne cycloaddition (CuAAC)
reaction. A functional solvent was chosen via a COSMO-RS based method,
which allowed a one-phase reaction while facilitating a thermally
induced final product separation from the reaction mixture. To perform
azidation and CuAAC reactions in a microfluidic system, both azidation
reagent and Cu(I) catalyst were immobilized, on a packed bed and in the
hydrophobic membrane of polymer vesicles, respectively, as this allowed
a higher reaction efficiency, facile regeneration of azidation reagent,
and recovery of the metal catalyst. This ONE-FLOW process has great
benefits for the pharmaceutical industry in their quest to scalable,
efficient and safe synthetic processes with minimal waste generation.
Perception of Cityscape of the Central Part of Kaunas and Sociocultural Aspects Determining It
Authors: Vaitkutė Eidimtienė Vaida , Kamičaitytė Jūratė
Published: October 2021

This article deals with peculiarities of Kaunas centre cityscape perception and the determining socio-cultural factors. Important elements creating unique view of a location and identity are related to the period’s history, culture, political situation, features of the location natural basis, as well as individual’s-observer‘s education, personal qualities, aesthetic and cultural sophistication. The territory of Kaunas city centre was selected for the case study. It is characterized by unique natural, historic, cultural conditions and high information-emotional potential. During the research prioritary ranking concerning significance of cityscape elements groups and experienced psycho-emotional senses was conducted. Furthermore, the correlations between the distance of object observation, heights of observation points as well as movement mode selection and personal factors such as gender, age, occupation, and education based on statistical dependencies were identified. The obtained results explain the principles of Kaunas centre cityscapes perception.
Guest editorial - Pattern recognition, optimization, neural computing and applications in smart city
Authors: Chen Mu-Yen , Rubio Jose , Sangaiah Arun
Published: October 2021

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Primary microstructure characterization of Co-20Ni-9Al-7W-3Re-2ti superalloy
Authors: Tomaszewska A.
Published: October 2021

The characterization of the primary microstructure of the new Co-based superalloy of Co-20Ni-9Al-7W-3Re-2Ti type was shown in this article. The investigated alloy was manufactured by induction melting process from pure feedstock materials. The fundamental technological problem related to Co-Al-W-X multicomponent alloys casting process is a strong susceptibility to interdendritic segregation of alloying elements, especially tungsten and rhenium. The performed analysis revealed that the observed effect of alloying elements segregation was detectable and much stronger than for Co-9Al-9W and Co-20Ni-7Al-7W alloys, related to titanium, nickel, and aluminium migration to inter-dendritic spaces. Consequently, the tungsten concentration gradient between dendritic and interdendritic zones was higher than for Co-9Al-9W and Co- 20Ni-7Al-7W alloys. The same situation was in the case of rhenium and cobalt, but Co concentration in the interdendritic zone was only slightly lower.
Mechanical properties of phase-pure bulk Ta4AlC3 prepared by spark plasma sintering and subsequent heat treatment
Authors: Ying Guobing , Hu Cong , Liu Lu , Sun Cheng , Wen Dong , Zhang Jianfeng , Zheng Yongting , Wang Minghui , Zhang Chen , Wang Xiang , Wang Cheng
Published: October 2021

High-purity and bulk Ta4AlC3 ceramics were successfully fabricated by spark
plasma sintering (SPS) and subsequent heat treatment, using the raw
materials including TaC and Ta2AlC powders. These raw materials were first
synthesized by self-propagation high temperature synthesis from elements
tantalum, aluminium and carbon black powders, followed by pressure-less
sintering. The as-fabricated bulk Ta4AlC3 was relatively stable when
subjected to heat treatment at elevated temperature of 1500?C. Moreover,
prolonging the heat treatment time resulted in bigger grain sizes and higher
densities of the Ta4AlC3. The flexural strength and the fracture toughness
of the Ta4AlC3 fabricated by SPS were found to be 411MPa and 7.11MPa?m1/2,
respectively. After the heat treatment at 1500?C for 8 h, the flexural
strength and the fracture toughness of the Ta4AlC3 could reach 709MPa and
9.23MPa?m1/2, respectively. The special structural characteristics of the
ternary ceramics and the increase of density after the heat treatment are
the main reasons for the variation in mechanical properties of ternary
ceramics.
Effect of PEG-based binder concentration on the mechanical properties of lithium disilicate glass-ceramics prepared by low-pressure injection moulding
Authors: Kraipok Arnon , Intawin Pratthana , Kamnoy Manlika , Inthong Suchittra , Leenakul Wilaiwan , Bintachitt Patamas , Eitssayeam Sukum , Khamman Orawan , Tunkasiri Tawee , Pengpat Kamonpan
Published: October 2021

Lithium disilicate (LD) glass-ceramics are extensively employed in
restorative dentistry because their superior aesthetic properties and
hardness are similar to natural teeth. The aim of this work is to
investigate the mechanical properties and chemical solubility of lithium
disilicate glass-ceramics prepared by the low-pressure injection moulding
using the PEG-based binder. The glass-to-binder ratio was varied as 60:40,
55:45, 50:50 and 45:55 vol.%. The sintering conditions of 800?C with 2 h
dwell time were selected according to thermal analysis. Phase formation,
microstructure and mechanical properties of the prepared samples were
characterized by XRD, SEM, microhardness and three-point bending test,
respectively. Besides, the chemical solubility of the system was
investigated by the immersion test in acetic acid solution. XRD analyses of
the sintered sample confirmed the presence of only one prominent crystalline
phase of LD. SEM result showed that the porosity increased with decreasing
glass powder content. The mechanical properties of the LD glass-ceramic
samples tended to decrease when the proportion of the glass powder
decreased, while the chemical solubility tended to increase. The mechanical
properties of the glass-ceramics, i.e. the highest density value, Vickers
hardness and flexural strength were 2.55 g/cm3, 6.80GPa, and 176MPa,
respectively. These results could be useful in developing these LD
glass-ceramics for their optimal use in dental applications.
Study of composite TiN/Ag/Cu2O/TiO2 with improved photocatalytic performance
Authors: Shi Xinwei , Li Jing , Zhu Jingyu , Yang Yifan , Wang Xiaoxia , Zhu Bailin , Xu Liujie
Published: October 2021

TiO2 film has the advantage of good photochemical stability and it can be
used for self-cleaning glasses. However, due to the wide band gap, the
spectral response range of TiO2 film is restricted to the ultraviolet
region. In this work, based on the research of TiO2 thin films, multilayer
TiN/Ag/Cu2O/TiO2 films were designed and successfully prepared. The
structure and properties of the obtained samples were characterized by X-ray
diffraction, spectral ellipsometry (SE), atomic force microscopy (AFM) and
UV-Vis-NIR spectrophotometer. The results show that p-n heterojunction will
be formed between Cu2O and TiO2 in the multilayer film, thus reducing the
band gap of TiO2 film. Based on the analysis of the photocatalytic mechanism
of the multilayer films, a conclusion may be drawn that the designed
multilayer film is helpful to improve the photocatalytic efficiency of
titanium dioxide and expand its utilization of sunlight.
Bioglass-fibre reinforced hydroxyapatite composites synthesized using spark plasma sintering for bone tissue engineering
Authors: Rizwan Muhammad , Chandio Ali , Sohail Muhammad , Bashir Nasir , Yousuf Sumra , Alias Rodianah , Rehman Hammad , Hamdi M. , Basirun9 Jeffrey
Published: October 2021

Hydroxyapatite (HA) exhibits several desirable characteristics, but it still
lacks osteoinduction, which is a necessary requirement for a bone scaffold.
HA-based composites with different amounts of Bioglass? (BG) were prepared
using spark plasma sintering (SPS). Careful selection of the SPS parameters
avoided undesirable reactions between the calcium phosphate (CaP) and
bioglass (BG present in the form of powder and fibres), as confirmed through
X-ray diffraction analysis. Scanning electron microscopy images of the
composite scaffolds revealed a fibre like appearance of the glassy region.
The in vitro bioactivity and biodegradation analyses were performed by
immersing the composites in simulated body fluid (SBF) and
tris(hydroxymethyl)aminomethane (Tris), respectively. The ability to obtain
only the CaP phase and glassy phase with desirable bioactive and
biodegradation behaviour, indicated that these SPS scaffolds can be employed
as bone scaffolds for clinical trials, after further in vivo analyses.
Metrological support of maintenance by the technical state of communication means
Authors: Ryzhov Yevhen , Sakovych Lev , Myroshnychenko Yurii , Hrabchak Volodymyr , Nastishin Yuriy , Volobuiev Anatolii
Published: October 2021

Modern and prospective communication means are among the most knowledge-driven, high-tech types of industrial products, which are subject to enhanced requirements for quality and efficiency of application. The effective functioning of modern communication means is provided by built-in software, including metrological support. In this paper, we consider the specifics of metrological maintenance of large-scale communication facilities (tens and hundreds of thousands of elements) consisting of separate subunits, the serviceability, maintenance, and recovery of which can be performed autonomously. It is proposed to enhance the efficiency of the by-state-maintenance (also called maintenance by the technical state) by accounting for the specifics of metrological support, establishing an optimal sequence of operations, selecting the measuring instruments in accordance with relevant requirements. To do this, one has to use a combined indicator composed of individual parameters of the tests and the probability of their preferred choice. This allows to assess the technical condition of the communication means with a given probability during a minimal time. In addition, one can estimate the time of maintenance, taking into account the metrological reliability and the probability of correct evaluation of the result of checking the parameters by the measuring instruments. The order of implementation of the obtained results is formalized in the form of an algorithm and an example of their realization is presented.
Can Japan Meet Its 2030 Nuclear Power Target?
Authors: Zissler Romain , Cross Jeffrey S.
Published: October 2021

The 2010s marked a turning point in Japan’s nuclear power’s industry. In fiscal year 2010, nuclear power electricity generation stood at 288.2 terawatt-hours. In 2011, the Great East Japan Earthquake triggered a tsunami and a major accident at the Fukushima Daiichi nuclear power plant. In 2014, nuclear power electricity generation eventually bottomed out at 0 terawatt-hour due to the temporary closures of all the reactors. In 2015, Japan’s Government advanced its landmark Long-term Energy Supply and Demand Outlook targeting nuclear power electricity generation to reach 216.8-231.7 terawatt-hours in fiscal year 2030 – granting a key role to this technology in terms of low carbon and stable domestic electricity supply. However, confronted to the challenges of meeting more stringent safety standards, many nuclear reactors have been permanently shut down, and future restarts are unclear. Given this scenario, this paper demonstrates that meeting Japan’s nuclear power 2030 target is unlikely. Furthermore, Japan has recently set a net zero greenhouse gas emission goal by 2050 making decarbonization of its electrical power generation, a future need. Although improvements in energy efficiency and greater deployment of renewable energies are two potential ways to overcome the shortfall, this paper discusses how proposed international electrical interconnections may serve as efficient and economical alternatives to meet nuclear power’s expected shortfall that also addresses climate change mitigation, electricity security strengthening, and resiliency.
Determination and description of endogenous and exogenous factors of the financial services market development in the conditions of economic turbulence
Authors: Dubyna Maksym , Panchenko Olena , Bazilinska Olena , Pylevych Dmytro , Kozlianchenko Olena , Konoplia Nataliia
Published: October 2021

The aim of the study is to determine and describe endogenous and exogenous factors in the development of financial services in a turbulent economic environment. In the study, the authors used general economic and specific methods of scientific knowledge, including: formalization, abstraction, dialectical, graphic, decomposition, monographic, analysis and synthesis, abstract-logical, generalizations, observations, comparisons and others. The article systematizes and analyzes the basic factors that determine the development and functioning of the financial services market. It is proved that an important role in the development of the financial services market is played by economic factors, among which the authors selected certain groups and studied the peculiarities of their formation.
PENGARUH MANFAAT, KEPERCAYAAN DAN KEMUDAHAN PENGGUNAAN TERHADAP MINAT NASABAH MENGGUNAKAN MOBILE BANKING DI BANK MEGA SYARIAH CABANG PALU
Authors: Nurdin  , Rukma Ningrum  , Sofyan Bacmid  , Abdul Jalil
Published: October 2021

Pada era teknologi informasi sekarang ini perilaku nasabah atau konsumen banyak berubah dalam melakukan transaksi perbankan, dimana nasabah sangat mengedepankan aspek kemudahan, fleksibilitas, efisiensi, dan kesederhanaan. Teknologi mobile banking merupakan salah satu jenis pelayanan yang diberikan Bank MEGA Syariah kepada nasabahnya agar nasabah dapat melakukan transaksi perbankan kapan saja dan dimana saja setiap saat tanpa harus dating ke bank yang bersangkutan. Jenis penelitian ini adalah penelitian kuantitatif dengan sifat asosiatif. Sumber data dalam penelitian ini adalah data primer dan data sekunder. Sampel penelitian ini sebanyak 62 responden yang diambil dengan teknik incidental sampling. Teknik pengumpulan data menggunakan kuesioner dan wawancara. Metode analisis data menggunakan uji regresi linier berganda. Dari hasil uji t menunjukkan bahwa variabel manfaat memiliki nilai Thitung sebesar 1.378 < 1.988, maka H1 ditolak, variabel kepercayaan memiliki nilai Thitung sebesar 2.208 > 1.988, maka H2 diterima, variabel kemudahan penggunaan memiliki nilai Thitung sebesar 1.785 < 1.988, maka H3 ditolak. Dan hasil uji R2 sebesar 0.301, hal tersebut berarti variabel minat nasabah dapat dijelaskan oleh variabel manfaat, kepercayaan, dan kemudahan penggunaan. Secara parsial dari tiga variable yang diuji tidak satupun mempengaruhi minat nasabah menggunakan mobile banking.
Glossário dos Hermetica Græca: pesquisa bibliográfica das ferramentas e das fontes secundárias de tradução
Authors: Lira David Pessoa de
Published: October 2021

O Glossário dos Hermetica Græca compreende 500 entradas ou lemas extraídos das ocorrências no Greek-English Lexicon de Liddell-Scott-Jones (LSJ), no Diccionario Griego-Español (DGE) de Francisco Rodríguez Adrados e no Greek Lexicon of the Roman and Byzantine Periods de Apostolides Sophocles. Predominantemente, são palavras que procedem das duas maiores coleções herméticas, a saber, do Corpus Hermeticum e dos Stobaei Hermetica. Este trabalho, por meio de uma pesquisa bibliográfica, objetiva apresentar os instrumentos de trabalho disponíveis para a tradução dos Hermetica Græca. A pesquisa perscruta e examina as fontes secundárias, a saber, dicionários e léxicos gerais da língua grega, com a finalidade de encontrar lemas que remetem aos Hermetica Græca, classificá-los e quantificá-los.
Novedades florísticas para las comarcas de El Aljarafe y La Vega (Sevilla, España)
Authors: Salvador-Menéndez José Antonio , Campano Ángel , Romero-Zarco Carlos Manuel
Published: October 2021

Se dan a conocer algunas novedades florísticas para las comarcas de El Aljarafe y La Vega en la provincia de Sevilla (España).
Confirmation de la présence de Stipa apertifolia subsp. longiglumis (H. Scholz) Vázquez & Devesa (Poaceae) dans les Monts des Ksour (Aïn Sefra, Algérie)
Authors: Belkacem Gordo , Hadjadj- Aoul Seghir
Published: October 2021

Dans cette note, les auteurs confirment la présence de Stipa apertifolia subsp. longiglumis (H. Scholz) Vázquez & Devesa dans l’Atlas saharien occidental. De même, ils actualisent les connaissances sur son écologie, son statut de conservation et celui de son endémicité.
Eichhornia crassipes (Mart.) Solms, novedad en Sevilla (Andalucia, España)
Authors: García Murillo Pablo , Boniquito José Mª , Gutierrez González David , Castilleja López Francisco Javier , García de Lomas Juan
Published: October 2021

Se informa del hallazgo de la planta acuática exótica invasora Eichhornia crassipes en la Dársena o canal Alfonso XIII, un brazo regulado del río Guadalquivir, en Sevilla (S. de la Península Ibérica). Se trata de la primera cita de esta especie para la provincia de Sevilla y se añade a diversas referencias ocasionales que existían en Andalucía.
Medicago soleirolii (Fabaceae), especie a excluir de la flora ibero-balear
Authors: Sáez LLorenç , Mestre Edgard , Vicens Magdalena , Romero-Zarco Carlos Manuel
Published: October 2021

Se desestima la presencia de Medicago soleirolii Duby (Fabaceae) en el territorio de Flora iberica
Some type of semisymmetry on two classes of almost Kenmotsu manifolds
Authors: Dey Dibakar , Majhi Pradip
Published: October 2021

The object of the present paper is to study some types of semisymmetry conditions on two classes of almost Kenmotsu manifolds. It is shown that a (k, µ)-almost Kenmotsu manifold satisfying the curvature condition Q · R = 0 is locally isometric to the hyperbolic space ℍ2

n

+1(−1). Also in (k, µ)-almost Kenmotsu manifolds the following conditions: (1) local symmetry (∇R = 0), (2) semisymmetry (R·R = 0), (3) Q(S, R) = 0, (4) R·R = Q(S, R), (5) locally isometric to the hyperbolic space ℍ2

n

+1(−1) are equivalent. Further, it is proved that a (k, µ)
′
-almost Kenmotsu manifold satisfying Q · R = 0 is locally isometric to ℍ
n

+1(−4) × ℝ
n
and a (k, µ)
′-
-almost Kenmotsu manifold satisfying any one of the curvature conditions Q(S, R) = 0 or R · R = Q(S, R) is either an Einstein manifold or locally isometric to ℍ
n

+1(−4) × ℝ
n
. Finally, an illustrative example is presented.
Ichthyosis in Dogs—Congenital Dermatologic Disorder
Authors: Malinovská Z. , Čonková E.
Published: October 2021

The skin provides protective functions, such as thermoregulation, resorption, provision of immune responses, storage and sensory functions, which all play an important role in the internal stability of the organism. The skin has 3 major layers: the epidermis, the dermis and subcutis. The outermost protective layer of the epidermis, the stratum corneum, consists of 20 to 30 overlapping layers of anucleate cells, the corneocytes. Ichthyosis is an autosomal recessive congenital skin disease, in which the corneocytes form defects that appear like individual steps of the stratum corneum. Ichthyosis is characterized by excessive scaling over the entire body surface and is not curable; the symptoms can only be alleviated. Several genetic variants have been identified in specific dog breeds: PNPLA1 in the Golden Retrievers, SLC27A4 in the Great Danes, NIPAL4 in the American Bulldogs, TGM1 in the Jack Russel Terriers, ASPRV1 in the German Shepherds, which cause different forms of nonepidermolytic ichthyosis and KRT10 in the Norfolk Terriers, which causes epidermolytic ichthyosis. When classifying breeds of dogs predisposed to ichthyosis, it is necessary to determine the presence of defective genes in the genome of the individual animals involved in mating.
Impedance-based real-time monitoring of neural stem cell differentiation
Authors: Shah F. J. , Caviglia C. , Zór K. , Carminati M. , Ferrari G. , Sampietro M. , Martínez-Serrano A. , Emnéus J. K. , Heiskanen A. R.
Published: October 2021

We present here the first impedance-based characterization of the differentiation process of two human mesencephalic fetal neural stem lines. The two dopaminergic neural stem cell lines used in this study, Lund human mesencephalic (LUHMES) and human ventral mesencephalic (hVM1 Bcl-XL), have been developed for the study of Parkinsonian pathogenesis and its treatment using cell replacement therapy. We show that if only relying on impedance magnitude analysis, which is by far the most usual approach in, e.g., cytotoxicity evaluation and drug screening applications, one may not be able to distinguish whether the neural stem cells in a population are proliferating or differentiating. However, the presented results highlight that equivalent circuit analysis can provide detailed information on cellular behavior, e.g. simultaneous changes in cell morphology, cell-cell contacts, and cell adhesion during formation of neural projections, which are the fundamental behavioral differences between proliferating and differentiating neural stem cells. Moreover, our work also demonstrates the sensitivity of impedance-based monitoring with capability to provide information on changes in cellular behavior in relation to proliferation and differentiation. For both of the studied cell lines, in already two days (one day after induction of differentiation) equivalent circuit analysis was able to show distinction between proliferation and differentiation conditions, which is significantly earlier than by microscopic imaging. This study demonstrates the potential of impedance-based monitoring as a technique of choice in the study of stem cell behavior, laying the foundation for screening assays to characterize stem cell lines and testing the efficacy epigenetic control.