bluuebunny/crossref_metadata_2025 huggingface dataset:
SOMATO-PSYCHIC DISORDER CLINICAL CASE IN A FEMALE PATIENT WITH MULTINODULAR EUTHYROID GOITER
Authors: Tsyganenko Oksana
Published: September 2016

The article presents a clinical case of somato-psychic disorder in a patient with multinodular euthyroid goiter. The patient was diagnosed with thyroid cancer on outpatient basis and was suggested urgent surgical treatment. After receiving information about cancer pathology the patient developed symptoms of hypernosognostic neurotic syndrome with manifestations of obsessions and hystero-hypohondriasis. The patient was focused on the rigid hypochondria with detailed statement of the slightest signs of bodily distress.

Therefore, the above example demonstrates difficulty in selecting the tactics of management for such patients due to development of symptoms primarily determined by psycho-emotional tension. This category of patients should be followed not only by endocrinologists, surgeons, but the multidisciplinary team, including psychiatrists, and psychotherapists, since in case of combined impact of a number of adverse factors, the reaction to the disease can become so extreme that its management in the early stages of therapy seems no less important than the direct treatment of somatic condition.
THE MODERN APPROACH TO THE COMPLEX THERAPY OF DEMODICOSIS
Authors: Revenko Zhanetta
Published: September 2016

Demodicosis is one of the most common diseases of the skin. Despite the large number of scientific publications on this issue the question of the etiology and pathogenesis of this disease still remains unresolved and the development of more effective methods of treatment and prevention has not only medical but also social significance as patients preserving the working ability have actually long enough to be on outpatient and even inpatient treatment. In addition the long existence of the rash on the face that is the "business card" leads to the secondary sometimes severe neurotic disorders that results in reducing abilities, isolation, unwillingness to be in a team, family, etc.

We investigated the effect of complex therapy which had been conducted by means of antiparasitic, immunomodulatory, anti-inflammatory and desensitizing drugs in patients with demodicosis, as well as mandatory adjustment of changes in the hepato- panсreato-duodenal system. We examined 109 patients with demodicosis from 18 to 39 years old and 10 healthy individuals of the corresponding age and sex. It was established that the effectiveness of treatment of demodicosis based on the application of albendazole in the complex treatment along with immune-modulating therapy and hepatoprotection increased significantly. There has been a reliable rapid regression of clinical symptoms in most patients with demodicosis.
ALCOHOLIZATION IN THE STRUCTURE OF POSTSTRESS MALADJUSTMENT
Authors: Gaponov Konstantin
Published: September 2016

Analysis of the literature data on alcoholic addiction, poststress maladjustment and its combination revealed the significant number of common node moments in pathogenic mechanisms of its appearing and realization. It concerns biological mechanisms that are common for both processes and its activation at one of them provokes the development of the other. First of all it is stem structures of brain and neuroendocrine mechanisms of central and peripheral regulation and its activation is cross for stressor reaction and alcoholization. There was revealed the leading role of stressor reaction mechanisms and its association with poststress maladjustment in formation of psychological alcoholic addiction. There was constructed hypothetical model of development and functioning of association pathogenetic mechanisms with formation of comorbidity of analyzed pathological states.
THE USE OF PLASMAPHERESIS IN TREATMENT OF PATIENTS WITH INFERTILITY, PERITONEAL ENDOMETRIOSIS AND NAT2 GENE POLYMORPHISM
Authors: Dubinskaya Ekaterina , Lapteva Natalia , Lukyanova Yana
Published: September 2016

It is known that 30–40 % of patients with peritoneal endometriosis suffer from infertility. Half of the patients with endometriosis are identified point mutation in NAT2 – gene, which plays an important role in the acetylation of aromatic and heterocyclic amines, in the accumulation of endotoxins, activation of free radical oxidation, impaired microcirculation. These factors involve the use of methods of gemapheresis which have detoxification, the blood rheology corrective and immune corrective effects.
The purpose of this study was to evaluate the efficacy of therapeutic plasma exchange in treatment of patients with peritoneal form of endometriosis, infertility and point mutations in the gene NAT2.
The study included 140 patients with infertility, peritoneal form of endometriosis and point mutations in the gene NAT2. All patients are performed laparoscopy, coagulation foci of endometriosis. In the following 93 (66.4 %) patients were treated with a the course of therapeutic plasmapheresis using the apparatus «PCS-2» with the removal of 20–25 % the volume of circulating plasma with replacement plasma of crystalloid and colloid solutions. Before treatment were shown the signs of endotoxemia, activation of oxidative stress. After treatment with the use of plasmapheresis was revealed the significant reduction of endogenous intoxication parameters and oxidative stress. Also is noted the increase in the pregnancy rate, both independently and in IVF programs, especially during the first 3 months after treatment. The findings suggest that the efficiency of the proposed comprehensive treatment techniques (laparoscopy and subsequent course of therapeutic plasmapheresis) of patients with peritoneal endometriosis and infertility and with point mutations in the gene NAT2. The use of plasmapheresis is pathogenetically justified in patients of the studied group.
INFLUENCE OF VAGINAL ADMINISTRATION OF GLUCOSAMINE HYDROCHLORIDE TO PSYCHO-EMOTIONAL AND LOCOMOTOR ACTIVITY OF SPAY FEMALE RATS
Authors: Sinitsyna Oksana , Zaychenko Anna , Ryzhenko Iryna
Published: September 2016

The significant place in the menopausal syndrome and deficiency of estrogens takes psycho-emotional disorders. Psychosomatic disorders, difficulty of adequate evaluation and correction in menopausal women evidence the fact that this issue is important today. Severe symptoms of menopausal syndrome at violation of psycho-vegetative sphere appear in the early post-menopause, due to final termination of ovarian function and sharply deficiency of estrogens during this period. Intravaginal administration of glucosamine hydrochloride to spay female rats has moderate anti-depressant and anxiolytic effects, accompanied by reduction of the psycho-emotional behavioral reactions, normalization of locomotor activity of animals. As of totality of effects, the estriol reference drug is better than glucosamine hydrochloride. The data reveal prospects of vaginal gel glucosamine hydrochloride in the treatment of menopausal disorders of various origins.
ELABORATION OF ORGANIZATIONAL ARRANGEMENTS ON THE IMPROVEMENT OF FUNCTIONING OF THE SYSTEM OF PHARMACEUTICAL SUPPORT OF SUDAN POPULATION
Authors: Ievtushenko Elena , Abuzayid Osama Mohamed Nur Ahmed
Published: September 2016

In the article is considered the problem of support of Sudan population with available pharmaceutical production. The aim of research is an analysis of the price and assortment policy realized by the different pharmaceutical structures, determination of the level of their functions on guaranteeing the availability of medicaments, elaboration on the base of received results the arrangements on optimization of the pharmaceutical support system. It was determined that not all subjects of Sudan pharmaceutical market responsible for the pharmaceutical support cope with such problems at the proper level. Thus in the private drugstores, in the net drugstores of the Ministry of defense «Alia» and in drugstores of the health insurance system the prices of medicament exceed the recommended ones in more than 2 times, an assortment also does not corresponds to both internal and international requirements. The received results indicate the unreasonable use of budget means by the separate state structures, the negative tendencies in the system of guaranteeing the availability of pharmaceutical help.
It was established that the biggest suppliers of the medicaments in Sudan, excluding the state Centre of medicament support CMS cannot ensure the system of health protection with medicaments of the proper quality, assortment and the price rate.
There were elaborated the organizational-economic approaches to optimization of the structure of medical support of Sudan that include the change of the flows of medicaments distribution. There was offered the structure that unites all inflows in the aforesaid CMS and then distributes resources according to the needs of organizations and regions.
Introduction of the offered structures will allow improve the system of purchase and distribution of medicaments, make it transparent. The result of change will be the rise of physical and economic availability of medicaments, widening of assortment, decrease of the price of preparations, significant economy of budget resources.
CYPC19*17 POLYMORPHISM AS A RISK-FACTOR FOR NSAIDS-INDUCED ULCERS
Authors: Tkach Serhiy , Onischuk Lyudmyla , Balabanseva Alexandra
Published: September 2016

The new risk-factors for peptic ulcers induced by the use of nonsteroidal antiinflammatory drugs, such as polymorphism of different isoenzymes of cytochrome P450 were considered in the article. The aim of the research was to study different genetic polymorphism of several ferments CYP2C9 and CYP2C19 in inclination to NSAIDS-gastropathies by the way of estimation the risk of appearance of Helicobacter pylori (HP)-positive or Hp-negative NSAIDS- induced peptic ulcers, complicated or not with upper gastrointestinal bleeding.
124 persons were examined (76 men, 48 women in the age of 56,2+/–9,1 years) with Hp-positive or Hp-negative NSAIDS-induced peptic ulcers, that were performed genotyping of isoferments of cytochrome system (CYP2C9, CYP2C19). Based on investigations of 5 different isoenzymes (CYP 2C9*2, CYP 2C9*3, CYP 2C19*2, CYP 2C19*3 and CYP 2C19*17). It was founded that peptic ulcers are strictly associated only with CYP 2C19*17-genotype, possibly due to its involvement in arachidonic acid metabolism and gastroprotection. Thus, polymorphism CYP 2C19*17 can be considered as one of the risk factors for NSAID-gastropathy though the future researches are needed.
IATROGENIC AND ODONTOGENIC FORMS OF STOMATOGENIC MAXILLARY SINUSITIS. ULTRASOUND CHARACTERISTIC
Authors: Varzhapetyan Suren
Published: September 2016

The special features of transfer of information of the cone-beam computed tomography allows make conclusions about the character of pathological changes in maxillary sinuses only by the features of form and outlines of shadow of changed mucous tunic of sinus at its equal intensity that often leads to the incorrect interpretation of the results of research.

The high sensitivity of two-dimensional ultrasonography as for thickening (sclerosis) of mucous tunic, its edema (effusion) and exudation (purulent or serous) allows the more widen use of this method in addition to the cone-beam tomography at examination of maxillary sinuses. The other important moment is an absence of harmful influence of ultrasound on organism that makes it ideal for assessment of the dynamics of clinical course and allows prescribe it for pregnant and children.

The two-dimensional ultrasound examination of 86 patients with stomatogenic maxillary sinusitis (iatrogenic – 79,1 % odontogenic – 20,9 % forms) was carried out using ultrasound diagnostic apparatus АCUSON X 500, ATSmod.539 (SIEMENS, USA) in В-mode by the method of V.V. Shilenkova.

In the result of research was found out that sonographic picture of the maxillary sinuses at stomatogenic maxillary sinusitis depends on etio-pathogenetic form of disease. For iatrogenic form of maxillary sinusitis of stomatogenic origin are typical the ultrasound signs of chronic inflammation with many inflammatory inclusions in sinus, sclerosis of mucous tunic and serous effusion. By frequency prevailed: hyperechogenicity of membrane (30,8 %), its heterogenous echostructure (52,9 %), hyperechogenic character of content (39,7 %), arched outline of the back wall (36,8 %).

For odontogenic form of maxillary sinusitis of stomatogenic origin are typical the ultrasound signs of acute catarrhal inflammation with predomination of exudation in the mucous tunic and absence of contents in the lumen of sinus. By frequency prevailed: hypoechogenicity of membrane (27,8 %), its homogenous echostructure (45,6 %); acoustic shadow in sinus (72,2 %), arched outline of the back wall (27,8 %).
IODINE DEFICIENCY AND PATHOLOGY OF THYROID GLAND AS A BACKGROUND STATE OF CANDIDIASIS OF MUCOSA OF THE UPPER PART OF DIGESTIVE TRACT
Authors: Kushnirenko Inessa
Published: September 2016

There were examined 119 patients of gastroenterological profile, who, according to the results of microbiological examination of scraping from tongue and biopsy material of digestive tract and stomach, were divided into three groups: 1 group – patients with oropharyngeal candidiasis and surface candidiasis of mucous tunic, 2 group – patients with invasion of Candida fungi in mucous tunic, 3 group – patients without oropharyngeal candidiasis and without growth of fungi in biopsy material. The status of iodine provision was studied in 78 persons. The results of research revealed that at structural changes of thyroid gland the dominating position in patients with candidiasis of mucous tunic occupies the nodular goiter– 29,31% and 36,36% for 1 and 2 group respectively, whereas in 3 group the frequency of nodular goiter was 11,76%, at that hyperplasia and nodular goiter in patients with fungi invasion in mucous tunic was revealed 2,6 times more often comparing with patients without candidiasis (χ2=4,01; р<0,05). In patients with oropharyngeal and surface candidiasis and invasive candidiasis of mucous tunic of the upper part of digestive tract the hard degree of iodine nutrition deficiency with thyroglobulin level higher than 40 ng/ml was revealed in more than half of cases. At that the frequency of hard iodine deficiency at fungi invasion in mucous tunic 4,2 times higher comparing with patients without candidiasis of mucous tunic (F=0,024; р<0,05).

So, the concomitant comorbid state with pathology of thyroid gland and iodine deficiency is an aggravating factor in the course of candida infection that is necessary to be taken into account at clinical monitoring of patients with candidiasis of mucous tunic of the upper part of gastrointestinal tract.
LIPOFILLING OPPORTUNITIES IN BREAST CANCER SURGERY
Authors: Motuzyuk Igor , Sydorchuk Oleg , Kostiuchenko Yevhenii , Smolanka Ivan
Published: September 2016

In this article the authors described the experience of lipofilling usage at the National Cancer Institute.

Aim of this work was to improve the aesthetic results of surgical treatment of breast cancer patients by the usage of lipofilling in patients after breast reconstruction. The description of methods of lipofilling and their application in cancer patients, the benefits of usage of LipiVage® system was performed.

Materials and methods. The study included 42 women with breast cancer, who received special treatment in 2012–2016. The main group included 21 patients that have received special treatment and undergone lipofilling. The control group included 21 patients, who received only special treatment, (with no lipofilling). Different objective and subjective criteria for evaluating the effectiveness of lipofilling in achieving a satisfactory aesthetic result in patients, who underwent radical and reconstructive surgery for breast cancer, were used in this investigation.

The results shows that the implementation of lipofilling improves the aesthetic perception after breast reconstruction in 20 % of patients, decreases the number of complications after reconstructive operations and are not accompanied by a worsening of results of special treatment in breast cancer patients.

In conclusion it can be noted that our results show a high efficiency of lipofilling after special treatment, its safety and advisability for further usage.
USE OF METHODS OF MATHEMATIC STATISTICS FOR PROCESSING OF MEDICAL-BIOLOGICAL DATA FOR REVELATION OF THE ROLE OF CHEMICAL ELEMENTS IN ETHIOPATHOGENESIS OF HUMAN DISEASES
Authors: Prykhodchenko Anatolij , Ulianovskа Yulia , Ulianoskiy Vladislav
Published: September 2016

Aim of paper was to appraise the possibility of use of the traditional mathematical statistics methods for biomedical data to processing for determining the role of aluminium, chrome, niobium and lead in functioning of human blood-forming system. An effect of the abovementioned microelements on immunocompetent and blast cells was examined. Methods. To solve the indicated purposes, it were examined the venous blood leukoconcentrate in 48 of the examined persons. The standard methods of statistics were applied to the obtained data, namely the construction of spreading plot, elements of correlation and regression analysis. Results. It was obtained, that the reaction of immunocompetent and blast cells is ambivalent and depends upon the level of micronutrient status in human organism. Micronutrient biogenic effect is observed upon its low concentration in blood. An abiogenic effect arises upon the high level of micronutrient status in biological media of human. Conclusions. Notwithstanding the obtained results, the generally accepted approaches haven’t provided the possibility to determine the faithful character of immunocompetent and blast cells reaction on the level of micronutrient status in human organism and require the elaboration and development of the new approaches considering the revealed nonlinear relation.
SIZE STRUCTURE OF PHYTOPOPULATIONS AND ITS QUANTITATIVE EVALUATION
Authors: Skliar Victoria , Sherstuk Maryna
Published: September 2016

There was elucidated the original approach to the evaluation of phytopopulation size structure. For its characteristics it was offered to use the special index - index diversity of size structure (ІDSS). There are presented methods and algorithm of its determination. There was demonstrated that index diversity of size structure can be used at populational studies of species that belong to the different living forms. Especially phanerophytes (Pinus sylvestris) and hamephytes (Ledum palustre). As to Pinus sylvestris and Ledum palustre with help of index diversity of size structure was objectively proved that its cohorts and ontogenetic groups that growth in composition of forest phytocenoses typical for Ukrainian Polissya are not characterized with high level diversity of size structure. The value of index diversity of size structure is mainly less than 20 %. In phytopopulation the specific and phytocenotic peculiarity is demonstrated by diversity of size structure and also by representation of plants of certain size classes.
ELECTRON MICROSCOPIC STUDYING OF RAT BONE CELLS UNDER MICROGRAVITY CONDITIONS
Authors: Polkovenko Olga
Published: September 2016

In the experiments on rats (SLS-2) with the use of electron microscopy there was made the study of the osteoclasts population and the peculiarities of resorptive processes in a spongy bone of the epiphyses and the iliac crest.

The results of investigation permit to suppose that the processes of resorption of bone tissue become more intensive in zones of adaptive remodeling and destruction of the spongy bone under microgravity that is performed by several ways. One of mechanisms is the increasing of the functional activity of osteoclasts (appearance of "giant" osteoclasts). As a result it is the local demineralization and subsequent destruction of superficial areas of the bone matrix. The other mechanism is activation of osteocytic osteolysis was also investigated.
ARGINASE-BASED AMPEROMETRIC BIOSENSOR FOR MANGANESE IONS ANALYSIS
Authors: Stasyuk Nataliya , Synenka Mariya , Gayda Galina , Smutok Oleh , Gonchar Mykhailo
Published: September 2016

The development of simple cost-effective sensitive enzymatic methods for analysis of toxic metallic ions is an actual problem. Promising tools for elaboration of such methods are Mn2+-dependent enzymes. A novel manganese(II)-sensitive amperometric bi-enzyme biosensor based on of recombinant human arginase I (arginase) isolated from the gene-engineered strain of methylotrophic yeast Hansenula polymorpha and commercial urease is described. The biosensing layer with urease and apo-enzyme of arginase was placed onto a polyaniline-Nafion composite platinum electrode. The developed sensor revealed a high sensitivity to Mn2+-ions – 9200±20 A/(M∙m2)with the apparent Michaelis-Menten constant derived from Mn2+-ions calibration curve of 11.5±1.0 µM. A linear concentration range was observed from 1 µM to 6,5 µM MnCl2, a limit of detection being of 0.15 µM and a response time – 2.5 min. The proposed biosensor may be useful to monitor manganese compounds in laboratories of medicine, food industry and environmental control service.
IN SILICO MODELING OF THE REDOX METABOLISM IN HUMAN ERYTHROCYTES
Authors: Dotsenko Olga
Published: September 2016

There was elaborated the mathematical model of erythrocytes metabolism, including glycolysis (Embden-Meyerhof pathway), pentose phosphate pathway, metHb restoration pathway, Н2О2 metabolism reaction. The final model includes 50 reactions and 60 metabolites. Within the model was studied the change of activity of some enzymes and concentrations of metabolites in stationary state, that take part in the processes of utilization of oxygen active forms and restoration of metgemoglobin, depending on amount of exogenous and endogenous Н2О2. There was demonstrated the threshold character of changes of the many studied parameters, that testifies that the cells can be practically in physiological state at the change of external conditions for rather long time.

There was carried out an assessment of redox-state of erythrocytes at oxidizing load: was demonstrated the change of EGSSG/2GSH, ENADP+/NADPH and ENAD+/NADH from the concentration of endogenous Н2О2. There was established that in the studied diapason of concentrations of endogenous Н2О2 was observed the high slope of the change of EGSSG/2GSH, that was not observed for ENADP+/NADPH and the other redox-pairs.

The results of modeling coincide with existing views on the functioning of enzymes of antioxidant protection in human erythrocytes and testify to the possibility of practical use of the model
CYTOGENETIC EVALUATION OF THE DRINKING WATER TOXICITY
Authors: Vergolyas Maya
Published: September 2016

There was considered the use of biotesting for the assessment of the quality of drinking water from the different water supply sources (artesian, packaged and water-pipe one). The method consists in determination of the toxicants action on the specially selected organisms in the standard conditions with registration of changes at behavior, physiological, cellular and subcellular level using hematological indices of fish, frogs, rats and the lymphocyte cultures of the peripheral human blood. Physical-chemical methods determine only the presence and number of chemical elements in the tested water samples because of the very large number of possible combinations of chemical compounds in water solutions (more than 75 million combinations), including behavior of anthropogenic compounds and the natural vulnerability of the water ecosystems to the combined effects from its toxic influence.

As the optimal set of determination of the some structural and functional changes of cell genome as the result of the toxic influence of combination of the chemical compounds in the water solutions was offered the micronuclear test and leukocytic formula of the fish, frog and rat blood as biomarker. The reaction of fish, frog, rat test-organisms on the toxic irritation is presented in the change of qualitative content of the cells of peripheral blood. There were demonstrated the prospects of the use of hematological indices of the following test-organisms: Danio rerio fishes, Xenopus clawed frogs, Wistar rats and also the lymphocytes cultures of the human peripheral blood. The special attention was paid to the assessment of the risk for human health of the toxic substances in drinking water, genotoxicity and cytotoxicity that are revealed using hematological indices of animal cells. The universality of cellular organization opens the wide possibilities for toxicological studies using peripheral blood of the different groups of animals (fish, frogs, rats), human lymphocyte cultures and allow assume the following possibility of extrapolation of the received results on human organism
ASSESSMENT OF RICE SORTS AND HYBRIDS ON THE SALT TOLERANCE USING LABORATORY METHODS
Authors: Kostylev Pavel , Kudashkina Ekaterina
Published: September 2016

The article presents the results of the analysis of salt tolerance in rice samples by the laboratory methods at a concentration of NaCl – 1,5 %. The plants were grown in an incubator at temperature 26 °C. After 15 days, we measured the length of roots and shoots; the germination of seeds was counted. For the analysis of hybrids sensitive to salt Krasnodar varieties Novator with lines IR 52713-2B-8-2B-1-2, IR 74099-3R-3-3, NSIC Rc 106 – donor locus salt tolerance Saltol, using markers RM 493 and RM 7075. 90 plants were selected from the F2 plants which are analyzed by PCR, and the results of DNA analysis identified 6 of them as salt tolerant samples homozygous for the desired locus. From their offspring was selected the promising form to create salt-tolerant rice sorts.
STABILITY AND MORPHOLOGICAL CHARACTERISTICS OF LIPID - MAGNETITE SUSPENSIONS
Authors: Alexandrov Alexandr , Tsykhanovska Iryna , Gontar Tatуana , Kokodiy Nicholas , Dotsenko Natalia
Published: September 2016

The study of stability of lipid-magnetite suspensions (LMS) was carried out using photometry and electronic microscopy. All suspensions are rather stable in time. The best results in stability were demonstrated by suspensions with ratio Fe3O4: SAS=0,02:0,35 g or 0,04 mass % : 0,70 mass % and 0,025: 0,35 g or 0,05 mass % : 0,70 mass %. The sizes of magnetite particles from SAS were determined as– ~76 nm.

It was established, that with time (0–48,0 hours) and growth of wave length (210 – 1000 nm) is observed the gradual increase of transmission coefficient from 25 % (210 nm) to 71,9 % (1000 nm) at 0 hours of suspension ageing; from 27,5 % (210 nm) to 81,2 % (1000 nm) at maximal time of suspension ageing (48 hours).

There parameters of LMS were determined: concentration of particles – N=1,43 ∙ 1012 cm-3, in 48 hours concentration decreased by 20 % (N=1,19∙1012 cm-3); r=38 nm, n=1,48, κ=0,01. The function of particles distribution by sizes is rather narrow and symmetric that certifies the system of synthesized nanoparticles as homogenous with low degree of polydispersity.

Ultraviolet spectrums of LMS and their components were fixed and analyzed. Comparison of transmission spectrums of suspensions with different degree of dilution testifies to the chemical identity of samples.

There were studied kinetic dependencies of transmission coefficient for suspensions with different magnetite concentration (Fegen), on which base was calculated the effective radius of particles of stabilized magnetite: 76–168 nm. The mean radius of particles in lipid suspension of magnetite without stabilizer (reff)=400 nm. Visually LMS manifested the high aggregative stability with high sedimentation time 48 hours.

It was established, that LMS can be used as biologically active and feed additives with complex effect: manifest antioxidant activity, are the source of easily assimilated iron, improve quality and increase storage terms of fat-containing products. Thus, introduction of LMS in foodstuff improves its quality, nutritive and biological value.
Investigation of relationship between personality characteristics and career management of Melli Bank staff, Iran
Authors: Yavarpour Houshang , Hadi Peykani Mehraban , Gholizadeh Azar
Published: September 2016

Modern organizations provide their required goods and materials easily from other organizations and even other countries and the only resource that can’t be exchanged ideally is human resources, such that an efficient and standard human resources is the most important competitive capital of a country. According to this, current research aims to explain the relationship between personality characteristics with career management of Melli Bank staff in Iran. Statistical population of this research is all employees of Melli Bank central branches which are located in Tehran city. The number of Melli Bank central branches’ employees is 2603 and the total number of branches is 28 and an appropriate group sampling method is applied. The research method is descriptive-correlation type. For data gathering, two questionnaires of career path based on Shine model and personality characteristics questionnaire were used. The results show that there is a positive significant relation between the variables of emotional stability personality with the regression coefficient of 0.143, compatible personality with the regression coefficient of 0.110, experience- oriented personality mode variable with the regression coefficient of 0.231 and work ethic personality with the regression coefficient of 0.143 and career management of Melli Bank employees. But there is no significant relation between extroversion as one of the personality characteristics and employees’ career management.
Keywords: career dimensions, career anchors, personality characteristics, Melli Bank. JEL Classification: M10, M12, J24
Our Experience in Diagnosis and Treatment of Children with Biliary Atresia
Authors: Kulyk O. , Kurylo H. , Nykyforuk O. , Hrytsak D.
Published: September 2016

Biliary atresia is a congenital disease that occurs with lesions of the bile ducts leading to the development of cholestasis and manifests in the neonatal period. Without timely surgical treatment, patients with this pathology die during the first year of liver failure, esophagus bleeding or infections.The objective of the research was to analyze the results of examinations and treatment of 21 children with biliary atresia who were treated at the surgical department of conformational abnormalities in children in Lviv City Children’s Clinical Hospital since 2008 to 2015.Methods of the research included follow-up, laboratory ones, duodenal intubation, ultrasound, scintigraphy, MRI, diagnostic laparoscopy, liver paracentesis, determination of hepatitis B and C markers, DNA of CMV virus.Results of the research. Among the examined children biliary atresia was diagnosed in 18 patients at the age under 2 months. All children were operated timely. 6 patients needed liver transplantation. Diagnosis was made in 3 children under the age of 3 months. The Kasai onoperat was conducted in 2 children. All 3 children needed liver transplantation. Children with satisfactory quality of life after liver transplantation are on permanent immunosuppressive therapy. They have signs of biliary cirrhosis and undergo periodically inpatient treatment of an ascending cholangitis.Maintenance of normal nutritional (food) status, biliary tract patency and prevention of cholangitis and infections are the primary task in the course of postoperative treatment (The Kasai procedure).Conclusions. Early diagnosis of biliary atresia and timely conducted surgical treatment (under 2 months of age) makes it possible to improve the prognosis, neurological status, quality of life and to prevent the necessity of liver transplantation at an early age.
Changes of the Immune Status in Patients with Purulent Peritonitis
Authors: Savolyuk Serhiy I , Gudz Maksim A , Zhmur Andriy A
Published: September 2016

The analysis of cellular and humoral immunity indicators in the blood of patients with purulent peritonitis (PP) with the determination of their diagnostic value while determining the stage of peritonitis was performed. The levels of CD3, CD4, CD8, CD4 / CD8, CD19, CD16, CD95, CD25, IgA, IgM, IgG during hospitalization of 126 patients with PP was investigated. Monitoring of immune responsiveness stated regular changes in cellular and humoral immunity caused by the influence of cytokine profile, describing immunosuppression, the extent of which depends on the length and stage of PP. The progressive deepening of PP stages (in reactive and toxic stage) led to an increase in white blood cell count, CD95, due to the influence of dose-dependent increase in IL-6, CD19, IgM, G, and NK-cells (CD16) and CD25, the dynamics of which is closely related and dependent of IL-2.This was accompanied by a progressive lymphocytopenia, a decrease in CD3, CD4, which at constant or slightly increasing concentration led to decrease in CD8 IRI (CD4 / CD8) caused by the impact of immunosuppressive IL-6, stepwise reduction of IgA. Severe secondary immunodeficiency was observed in patients with end-stage PP and lymphocytopenia progressed along with the growth of white blood cell and marker CD95 with disruption of T-lymphocytes subsets (CD4 decrease at a constant or insignificant growth of CD8) with critical IRI indicators. The decrease in CD25, CD16 and CD19 dysfunction with sharp inhibition of the antibodies synthesis – decrease in IgM and G, A concentrations was also determined.
IMPLEMENTASI MANAJEMEN PENDIDIKAN INKLUSIF DI SD NEGERI GADINGAN WATES DAN MI MA'ARIF PAGERHARJO SAMIGALUH
Authors: Karana Dian Putera
Published: September 2016

Penelitian ini bertujuan untuk mengetahui: (1) keefektifan manajemen pendidikan inklusif (MPI) dilihat dari standar pelayanan minimum, (2) perbedaan MPI di SD negeri dengan MPI di SD swasta, (3) hambatan dalam pelaksanaan MPI, dan (4) solusi dan rekomendasi untuk menyelesaikan hambatan yang terjadi dalam pelaksanaan MPI. Penelitian ini menggunakan pendekatan penelitian evaluasi dengan model discrepancy. Responden penelitian berjumlah 41 orang. Data dikumpulkan menggunakan angket dan dianalisis menggunakan metode analisis deskriptif yang disajikan dalam bentuk angka dan persentase, di mana data yang berwujud angka-angka tersebut selanjutnya diterjemahkan dalam kata-kata atau kalimat. Hasil penelitian sebagai berikut. (1) MPI di SDN Gadingan dilihat dari standar pelayanan minimum telah mencapai skor 1002 (88,36%) dengan kategori sangat baik; dan di MI Ma’arif Pagerharjo telah mencapai skor 812 (75,19%) dengan kategori baik. (2) Perbedaan MPI di SDN Gadingan dan MI Ma’arif Pagerharjo terletak pada komponen standar: pendidik dan tenaga kependidikan, sarana dan prasarana, serta pembiayaan. (3) Hambatan: belum adanya pedoman penyelenggaraan pendidikan inklusif, minimnya jadwal guru pembimbing khusus untuk mendampingi guru reguler, minimnya anggaran, terbatasnya sarana dan prasarana. (4) Solusi: menyusun pedoman penyelenggaraan pendidikan inklusif, menambah waktu/jadwal guru pembimbing khusus untuk mendampingi guru reguler, mengusulkan penambahan anggaran dan memenuhi sarana dan prasarana, serta rekomendasinya: pengembangan wawasan dan pengetahuan pendidik dan tenaga kependidikan, optimalisasi pengelolaan sarana dan prasarana, dan pemenuhan kebutuhan anggaran/pembiayaan.
PROFESIONALISME GURU PENDIDIKAN KHUSUS DI DAERAH ISTIMEWA YOGYAKARTA
Authors: Pramantik Ida Ayu Dian , Pardjono Pardjono
Published: September 2016

Penelitian ini bertujuan menggambarkan profesionalisme guru pendidikan khusus di Daerah Istimewa Yogyakarta. Hasil penelitian profesionalisme guru pendidikan khusus berkaitan dengan: profesionalisme guru pendidikan khusus. Profesionalisme guru pendidikan khusus ditinjau berdasarkan empat kompetensi, yaitu: 1) kompetensi pedagogik, keempat subyek membuat perencanaan pembelajaran. Subyek SMR memahami kondisi siswa dan memandirikan siswa, sedangkan subyek BP berupaya memandirikan siswa; 2) kompetensi kepribadian, keempat subyek menunjukkan sikap sebagai panutan, disiplin, bekerja dengan ikhlas. Tiga subyek, selain subyek BP, memberikan pengabdian yang tulus, tanggung jawab terhadap pekerjaan, berpikir positif, dan menjaga kepercayaan; 3) kompetensi sosial, subyek HT dan SMR mewujudkan dengan sikap tidak diskriminatif, sedangkan subyek BP dan BSN mewujudkannya dengan lebih berperan aktif dalam kegitan di masyarakat; 4) kompetensi profesional, keempat subyek menunjukkan dengan belajar terus menerus, mengikuti workshop dan diklat, serta menulis buku dalam bidang pengembangan pembelajaran. Subyek SMR juga menunjukkan dengan mengikuti lomba, sedangkan subyek BP dengan menempuh jenjang pendidikan yang lebih tinggi dan mengikuti kegiatan organisasi kependidikan. Bentuk pengembangan profesionalisme yang dilakukan oleh seluruh guru subyek nampak jelas dalam kompetensi profesional, yaitu melalui kegiatan workshop, diklat, lomba, berorganisasi, maupun pengembangan yang dilakukan secara pribadi seperti menulis, dan menempuh pendidikan lanjut.
Incorporating Sustainable Development Objectives into Development Plans
Authors: Abdullah Muhammad Faris , Ariffin Ishak
Published: September 2016

Efforts aimed atdelivering sustainable development and promoting nature conservation in the planning and decision-making system in Malaysia has begun since the late 1970s. The growing importance of the preservation and protection of the environment against degradation have been highlighted in the Five year Plans since 1980s. Over the same period, a series of strategies for sustainability, entitled Conservation Strategies, was also being prepared in Malaysia, culminating in a National Conservation Strategy (NCS) in 1993. These strategies for sustainability were aimed at providing the framework for sustainable development. The general consensus is that prevention is better than remedial action. Potential impacts must be addressed at the planning stage before development decisions are made.Impact assessment is seen as a tool for preventive action in the quest for sustainable development. Although environment impacts assessment (EIA) was made mandatory for a lisst of prescribed activities since 1987, environmental degradation continued . This paper gives brief introduction to strategic environmental assessment (SEA) and tries to demonstrate how SEA can bridge the gaps and counteracts the limimtations of EIA and more effectively integrate the sustainable development objectives into the development plan system.
PLANNING FOR HERITAGE TOURISM: THE CASE OF LANGKAWI GEOPARK
Authors: Puay Liu Ong , Abd Halim Sharina
Published: September 2016

The principal building blocks underlying Langkawi’s status as a tourist destination and a geopark are its nature and culture. Both these resources provide the platform for Langkawi to grow as a tourist destination since 1980s and receiving the geopark status by GGN and UNESCO in 2007. This paper discusses that while tourism is a commercial enterprise, it has an important role in ensuring Langkawi’s natural environment is well-protected, and local communities’ cultural traditions safeguarded. Central to this need for protection is ‘heritage’ - the basic ingredient in sustaining Langkawi as a premier tourism destination. This necessitates the need to view tourism and heritage management as interdependent, as both rely on the same ‘heritage resources’. Planning can act as the bridge to connect tourism, whose products are identified for their extrinsic values as tourist attractions, and heritage in which assets are identified for their intrinsic values to a community, state, country and the world.
PLACEMAKING, PLACE NAMES, AND LOCAL MYTHS AND LEGENDS
Authors: Abdul Aziz Rahimah , Puay Liu Ong
Published: September 2016

Place names can reveal a great deal about the history and cultural heritage of any populated area, besides unlocking a valuable store of information. Place name is also an important element in placemaking. It employs imagination, experiences etc which are then narrated and shared. These place names contribute towards creating a sense of place and identity and when they are erased or changed would lead to a loss of valuable heritage. As such, when engaging in placemaking of built environment or changing place names planners should build upon origin of place names, which form part of cultural heritage. Focusing on the origin of some place names found on the Langkawi island such as ‘Kuah’ (‘gravy’), ‘Belanga Pecah’ (‘broken pot’), and ‘Air Hangat’ (‘hot water’), this article recommends that planning and placemaking in Langkawi Geopark be built upon these names, thus enhancing the sense of place as well as the sense of history of the local population.
INTRODUCING NETWORKS IN PLANNING: AN EXAMPLE FROM LANGKAWI
Authors: Geraldine Chan K.L , Hashim Halimaton Saadiah , Aziz Sarah
Published: September 2016

This article introduces networks as a potential technique in participatory planning and implementation activities, including community activities, social events, projects, and conference events. This recommendation is backed by findings of some networks-like characteristics indicated in past and present work relationships between relevant government and private stakeholders in a study of a few Langkawi Geopark activities. The findings were obtained from an analysis of some geopark activities and interview data given by various public and private stakeholders. The relationships had led to the successful completion of various geopark activities. This article argues that the relationships have the potential to be developed into effective networks of relationships in future geopark activities. Therefore, relevant authorities, policy makers, managers, administrators and planners could consider developing existing stakeholder relationships into actual networks in their future consultation programmes with all stakeholders. This could be achieved by using networks as a technique in planning and development.
SUSTAINABLE GOVERNANCE IN RELATION TO THE FINANCIAL ASPECT IN MANAGING COASTAL AREAS: MALAYSIAN EXPERIENCE
Authors: Asmawi M. Zainora , Mahamod Lukman Hakim , Mohamed Mohd Zin , Paiman Tuminah
Published: September 2016

Managing natural resources sustainably is essential in this contemporary era of land use planning system. This includes managing and planning theinvaluable of coastal areas. In this regards, coastal management programmes have been regarded as a key approach in delivering the coastal strategies and objectives towards achieving a sustainable coastal development worldwide. This is supported by the good governance to ensure that the implementation of coastal development is successful. As such, this paper suggests that the aspect of good governance as one essential element of coastal management that can and should make a substantial contribution to planning and managing coastal land uses in Malaysia. It has many positive implications to the environmental, social and economic sectors. The experience of Lembaga Urus Air Selangor (LUAS) in managing the coastal areas via the implementation of good governance indicates the requirement of good governance in ensuring a successful coastal management. In addition, financial element has become a significant attribute in implementing coastal management initiatives. This study offers input in planning literatures by addressing the integration of coastal management, good local governance, land use planning and financial elements which are very relevant with today‘s current global changes on environment as a whole.
RESIDENTIAL SATISFACTION - CONCEPT, THEORIES AND EMPIRICAL STUDIES
Authors: Mohit Mohammad Abdul , Al-Khanbashi Raja Adel Mahfoud Mubarak
Published: September 2016

Residential satisfaction, defined as the feeling of contentment when one has or achieves what one needs or desires in a house, is an important indicator and planners, architects, developers and policy makers use it in a number of ways. There are three theories – housing needs theory, housing deficit theory and psychological construct theory, and most empirical studies have used these theories or a combination of these theories in their research design. A number of variables representing housing and neighbourhood characteristics, individuals‘ socio-demographic attributes as well as their perceptions of housing and neighbourhood conditions have been analysed in most empirical studies what stand to indicate that further studies are required until a general theory of residential satisfaction/ dissatisfaction emerges. Also, a host of variables belonging to housing and its environment including the sociodemographic attributes of residents exert significant influences on the level of residential satisfaction/dissatisfaction which is however, culture and value specific indicating that further studies on residential satisfaction/dissatisfaction can be undertaken on case specific context to gude public policies on housing.
THE REVIEW FOR THE USE OF URBAN CLIMATIC MAP IN THE LAND USE PLAN FOR URBAN PLANNING
Authors: Ibrahim Ilyani , Abu Samah Azizan , Fauzi Rosmadi
Published: September 2016

Urbanization leads to positive and negative impacts on the society. While it accelerates economic growth, it also brings negative impact to the environment and people‘s health. The growth of urbanization is unavoidable; therefore, sustainability needs to be maintained to preserve the liveability of urban dwellers. The intention of this study is to review the use of climatic information in planning future developments in the local land use map. The studies of content and interview method were done in order to understand the real situation of this environmental mitigation. In further, the identification of the gaps of e study. The findings of this study were used to propose the climate indicators for the existing land use map. Future studies may focus on conducting preliminary experiments to apply the urban climatic map in the local context.
ANALYSIS ON COMMUNITY INVOLVEMENT IN CULTURAL ACTIVITIES: TRANSMISSION OF ETHNIC LANGUAGE
Authors: Abu Bakar Aisyah , Mohamed Osman Mariana , Bachok Syahriah , Ibrahim Mansor
Published: September 2016

This research reviews an analysis of Community Involvement in Cultural Activities specifically from the angle of transmission of Ethnic Language. Convention for the Safeguarding of Intangible Cultural Heritage (ICH) which has been adopted by UNESCO in October, 2003 has aimed to raise awareness at the local, national and international levels of the significance ICH, to ensure ICH is mutually respected by the communities concerned and to provide assistance for education and fund for the maintenance of this heritage. Survey Questionnaires have been recently conducted in one of the World Heritage Site, Melaka; to measure and determine the level of community involvement in cultural activities. The survey adopts five domains of ICH, Oral Tradition, Performing Arts, Knowledge, Social Practices and Traditional Craftsmanship in determining the involvement level of four cultured communities in their cultural enactments. These four communities are selected geographically. They are Morten Village Community, Portuguese Village Community, Heren and Jonker Streets Community and Gajah Berang Village Community. This paper acknowledges the significance, similarities and differences of the four cultured communities especially on transmission of ethnic languages with regards to community characters, specifically demographic and socioeconomic factors. Finally the analysis evaluates on the significance ethnic language transmission towards the overall cultural manifestations of the cultural communities.