bluuebunny/crossref_metadata_2025 huggingface dataset:
Flagship demonstration of industrial-scale production of nutrient resources from mealworms to develop a bioeconomy new generation
Authors: Kihanguila Whitley
Published: February 2025

Flagship demonstration of industrial-scale production of nutrient resources from mealworms to develop a bioeconomy new generation

Farmÿng will demonstrate a large-scale, first-of-its-kind bio-based value chain producing sustainable and premium feed ingredients from an innovative origin: the Tenebrio molitor larvae. Farmÿng will expand the technology from demo plant to industrial plant level to process them into proteins and lipids for fish feed and pet food end markets. Manure will be recovered for soil fertilisation applications.
The ERC-2020-Adv Grant Graff-IT Project
Authors: Tedeschi Carlo
Published: February 2025

The ERC-2020-Adv Grant Graff-IT Project

The ERC AdvGrant Graff-IT project aims to develop a new interdisciplinary approach to the study of medieval and Renaissance graffiti (seventh—sixteenth century) as a historical source. The project will have an innovative and groundbreaking effect on the study of graffiti in their multifaceted complexity: writing, image, language, and material aspects. Innovative tools and methods will be used to build out the first digital archive of Italian graffiti.
Migración de Dispositivo Intrauterino a Vejiga con Litiasis Secundaria y Manejo Endoscópico Exitoso
Authors: Petersen Erick , Salazar Carlos , Perez Sergio , Gaytán Giovanni , Estrada Herber , Sánchez Ingrid
Published: February 2025

INTRODUCCIÓN: El dispositivo intrauterino (DIU) es un método anticonceptivo frecuentemente utilizado por su alta eficacia y bajo riesgo. La perforación vesical y migración del dispositivo es una complicación rara que ocurre en un 0.1- 0.9%. Se manifiesta con síntomas urinarios inferiores e infecciones urinarias a repetición. OBJETIVO: Presentar un caso interesante de la extracción endoscópica de un dispositivo intrauterino con migración vesical y litiasis secundaria. MATERIALES Y MÉTODOS: Se presenta el caso de una paciente femenina de 43 años atendida en el Hospital General de Enfermedades del Instituto Guatemalteco de Seguridad Social, con disuria y dolor suprapúbico producido por un dispositivo intrauterino migrado. RESULTADOS: Se realizó una cistoscopía y extracción endoscópica de un dispositivo intrauterino migrado hacia la vejiga, asociado a litiasis secundaria. La evolución de la paciente fue satisfactoria sin evidenciar lesión uterina. CONCLUSIONES: En mujeres que presentan dolor suprapúbico, disuria o infecciones urinarias a repetición y que tengan el antecedente de uso de dispositivo intrauterino (DIU); a pesar de ser poco frecuente, se debe descartar la migración de este hacia la vejiga. El tratamiento se puede realizar con cirugía endoscópica y fragmentación con láser de la litiasis secundaria.
Pengembangan E-modul Berbasis Problem Based Learning untuk Memfasilitasi Higher Order Thinking Skills (HOTS) Siswa
Authors: Usi Usiminda , Oktaviana Dwi , Irvandi Wandra
Published: February 2025

The purpose of this study was to develop an e-module based on problem based learning to facilitate students' higher order thinking skills (HOTS) with the material taken being trigonometric comparisons. The research design used in this study was the ADDIE development model (analysis, design, development, implementation, evaluation). The subjects in this study were the development subjects and the product trial subjects. The development subjects were validators and the product trial subjects were students of class X Phase E1 of SMA Negeri 1 Belitang. The results of this study were: (1) the developed e-module obtained very valid criteria with media validity reaching 92% and material validity reaching 93%, (2) the e-module met practical criteria based on the results of student and teacher response questionnaires with practicality reaching 89.5%, (3) the effectiveness of the e-module was seen based on the results of the student posttest with an index percentage of 73.1% with effective criteria.
Effect of Supra Choroid Triamcinolone Acetate On Intraocular Pressure
Authors: Bukhari Sohail , Haseeb Uzma , Ahmed Nasir , Ahmed Israr , Ahmed Shoaib , Shah Shahid Hussain
Published: February 2025

Intraocular pressure is a critical parameter in maintaining the physiological function of the eye. Dysregulation of Intraocular pressure can lead to ocular pathologies. Objective: To evaluate change in intraocular pressure after supra-choroidal triamcinolone acetonide use. Methods: This prospective interventional studyas carried out at the vitreo-retina Department of Al Ibrahim Eye Hospital Karachi, ISRA Postgraduate Institute of Ophthalmology for six months from July to December 2023. Adult patients attending the vitreoretinal Outpatient Department with resistant macular oedema were included. Intraocular pressure readings at 1 week, 4 weeks, 8 weeks and 12 weeks were recorded and compared with baseline values by applying One-way ANOVA keeping the p-value of <0.05 as statistically significant. Data were analyzed using SPSS v 22.0. Results: Among all, 21 (46.67%) cases received injections to the right eye and 24 (53.33%) cases to the left eye. The mean intraocular pressure before injection was 12.07 ± 2.14 mmHg. At three months’ post-injection, the mean intraocular pressure was 13.60 ± 5.2 mmHg. For the right eye; the mean pre-injection intraocular pressure was 12.38 ± 1.96 mmHg. Three months’ post-injection, the mean intraocular pressure was 13.43 ± 5.59 mmHg (p<0.001). For the left eye; the mean pre-injection intraocular pressure was 11.79 ± 2.28 mmHg while three months’ post-injection, the mean intraocular pressure was 13.75 mmHg ± 4.96 (p-0.06). Conclusions: It was concluded that supra-choroidal triamcinolone injections increase intraocular pressure but stabilized over time. These findings support earlier trials and add to the evidence of this therapy's efficacy and safety.
Comparison of Open and Close Exposure with Orthodontic Traction of Impacted Maxillary Canine in Orthodontic Treatments
Authors: Amjad Bari Muhammad , Wajdan Nadia , Tariq . , Kanju Abid Hussain , Azeem Khan Muhammad , Liaquat Sahrish
Published: February 2025

Labial impactions make maxillary canines the most affected permanent teeth after third molars, at one third. Orthodontic advice is often needed for impacted canines. Objective: To compare the outcomes of open and close exposure with orthodontic traction of impacted maxillary canine in orthodontic treatments. Methods: In this comparative prospective cohort study 54 patients with labial impacted maxillary canine were included in this study. Study was conducted from Jan 2023- Jun 2023. Non-consecutive sampling technique was used. 27 patients were managed with open technique in group I and 27 patients with closed eruption technique in group II. The evaluation encompassed a comparison of two surgical exposure methods (open and closed) mobility, vitality, periodontal health, amount of impaction, length of orthodontic therapy, and postoperative discomfort. Results: Compared to the close eruption approach, the postoperative recovery time for open eruption was significantly greater (P < 0.05). Patients reported comparable levels of postoperative discomfort; but, the closed eruption approach resulted in a more rapid resolution of that pain. The open eruption approach required less time during surgery on average compared to the closed eruption technique (P <0.05). In a direct correlation with the amount of impaction, the overall length of orthodontic treatment was shown to be longer for deeper levels of impaction. Both methods produced canines with comparable levels of energy and movement. Conclusions: In this study, the closed eruption approach took longer but reduced postoperative pain faster. Orthodontic therapy took longer with deeper impaction. Closed eruption surgeries improve periodontal tissues surrounding guided erupted teeth.
Comparative Study on Histochemical Expression of CD34 in Different Variants of Ameloblastoma
Authors: Bashir Nasiha , Obaid Maria , Iqbal Fatima , Maryam Hoor , Naushin Tehmina , Khan Abbas Saleem
Published: February 2025

Ameloblastoma is a benign, locally aggressive, tumor of the oral cavity having a high propensity for recurrence. The growth potential of the tumor is linked to the proliferation of preexisting vasculature and is reflected in CD34 expression. has been rephrased as “Mean Vascular Density (MVD) which measures CD34 expression, aids in predicting this proliferation. Objectives: To evaluate the biological behavior of different variants of Ameloblastoma according to expression of CD34 and to correlate it with age and gender. Methods: The present study was analytical, cross-sectional study composed of total 40, already diagnosed cases of ameloblastoma. Immuno-histochemical expression of CD34 was analyzed. Results: Follicular variant has more growth potential in females 21 (62%) and males reveal more vascular growth in plexiform 19 (80%) acanthomatous (50%) and unicystic variant (50%). More endothelial proliferation in age group of > 40 years was seen in follicular variant, whereas, in age group of < 40 years, plexiform type was more dominant. However, relationship between the age groups and MVD scores were found to be insignificant (p > 0.05). Relationship between CD34 expression in ameloblastoma and its histological variants were also found to be statistically non-significant (p=0.9). Conclusions: All variants display highest Mean Vascular Density (MVD) score in posterior mandible. Follicular variant has more growth potential in females while in males it is found more in plexiform, acanthomatous and unicystic variants. More epithelial proliferation in the follicular variety is observed in the age group over 40, whereas more plexiform type was shown in the age group below 40.
Evaluating the Impact of Site of Oral Cancer on Quality of Life of Patients
Authors: Shah Syeda Gulrukh Saba , Shah Syeda Lalarukh Saba , Hameed Aamir , Khalil Zia Ur Rehman , Masood Aasim , Shah Farhana Jabeen
Published: February 2025

The Oral Health Impact Profile-14 was created to evaluate how oral health disorders affect the life of the patient, though it is widely utilized in patients with cancer, still, there is limited information regarding its measurement specifically related to the impact of cancer sites in a patient. Objectives: To evaluate the site of oral cancer and its impact on patients' oral Health-related quality of life. Methods: Diagnosed oral cancer patients were employed from the dental college of Peshawar, and 134 individuals were recruited. Patients of oral cancer, aged 20-59 of both genders were interviewed by using a convenience sampling technique. The Patients were asked about age gender, dental visit, site of cancer, treatment modalities, and various questions related to oral health impact profile. Data analysis was performed using SPSS version 26.0. Results: The study revealed that the majority of patients were aged 20-29 and predominantly male (67.9%), and most frequently occurs in the buccal mucosa (35.1%). The results revealed significant challenges among participants, with 30.6% experiencing difficulties in speech and 28.4% with a reduced sense of taste. Physical pain was reported by 38.8%, with 54.5% having eating uncomfortably. Conclusions: It was concluded that the study emphasized how patients' quality of life regarding oral health is greatly impacted by the location of cancer.
Predictors Of Antepartum Hemorrhage In Patients With Placenta Previa
Authors: Bashir Sadaf , Idrees Umbreen , Chughtai Hina Ameer , Arif Samia , Khatoon Nusrat , Tehseen Saema
Published: February 2025

Antepartum Hemorrhage (APH) is a significant complication in pregnancy that poses serious risks to both maternal and fetal health. Objective: To find the predictors of antepartum hemorrhage in patients with placenta previa among the local population of Pakistan. Methods: This cross-sectional study was conducted at PAF Hospital Mianwali from November 2023 to April 2024. A total of 208 patients were included in the analysis. Patients diagnosed with placenta previa confirmed through ultrasound examination were included in the study. Results: The mean age of the patients was 32.83 ± 4.56 years. Out of 208, there were 60 (28.8%) and nulliparous, 148 (71.2%) were multiparous. 85 (40.9%) had previous C-section and 30 (14.4%) were suffered from hypertension. 15 (7.2%) were diabetic and 180 (86.5%) were non-smokers. APH increased by 15% (Adjusted OR: 1.15, 95% CI: 1.05-1.26, p = 0.005). Furthermore, patients with a history of previous cesarean sections had over twice the odds of developing APH compared to those without this history (Adjusted OR: 2.12, 95% CI: 1.23-3.66, p = 0.007). Conclusions: This study concluded that advanced maternal age and a history of previous cesarean sections are significant predictors of antepartum hemorrhage in patients with placenta previa.
Prevalence of Medicolegal Cases During Covid-19 Pandemic Lockdown; A Local Experience
Authors: Murad Tasneem , Ahmed Sajjad , Ramzan Riffat , Ali Filza , Masood Riffat , Rana Sanaila Gull
Published: February 2025

Medical examinations are essential in legal cases, providing critical evidence that influences judicial outcomes. The COVID-19 pandemic impacted various societal aspects, including the nature and frequency of medical examinations. Objective: To compare the prevalence and types of medicolegal cases reported at District Headquarters Hospital, Rawalpindi, during the pre-pandemic and pandemic periods. Methods: A retrospective comparative cross-sectional study was conducted using data from March 2019 to August 2019 (pre-pandemic) and March 2020 to August 2020 (pandemic). Demographic details, including age and gender, as well as the types of cases (e.g., physical assault, sexual assault, trauma), were analyzed using SPSS version 24.0. Results: The total number of cases increased significantly from 389 in the pre-pandemic period to 441 during the pandemic (P < 0.01). During the pandemic, physical assault cases increased from 122 (31.36%) to 151 (34.24%), and sexual assault cases rose from 39 (10.02%) to 54 (12.24%) (P = 0.013). Blunt trauma cases increased from 79 (20.31%) to 101 (22.9%) and sharp trauma cases from 67 (17.22%) to 89 (20.18%). However, cases involving road traffic accidents (RTA) decreased significantly from 41 (10.54%) to 16 (3.63%) (P = 0.04). Poisoning incidents saw slight changes and the occurrence of burns, particularly chemical burns, increased from 3 (0.77%) to 5 (1.13). Conclusions: The COVID-19 pandemic lockdown has had a profound impact on the prevalence and nature of medicolegal cases. These findings emphasized the need for targeted interventions to address the specific medicolegal challenges exacerbated by pandemic conditions and to support vulnerable populations, particularly in urban areas and among women.
Impact of Anesthesia Type on Stone Clearance and Morbidity in Ureteroscopy: General Versus Spinal Anesthesia
Authors: Iqbal Atif , Saeed Syeda Javeriya , Liaqat Khurram , Ovais Fatima , Qamber Jawad Hussain , Nadia Sarah
Published: February 2025

Anaesthesiologists prefer regional anesthesia for ureterorenoscopy to prevent difficulties after the procedure, whereas surgeons prefer general anesthesia in order to prevent ureteral damage. However, limited comparative data exist regarding the outcomes of these anesthesia techniques in ureteroscopy-assisted stone clearance Objective: To compare spinal and general anesthesia regarding efficacy, safety, and patient outcomes during ureteroscopy for ureteric stones. Methods: This quasi-experimental study included 90 patients aged between 20-60 years in total were chosen.  Using a semi-rigid ureteroscope (8/8.4 fr), all individuals had ureteroscopic treatment for ureteric stones. Equal numbers of 45 patients were divided between the two groups. General anesthesia was administered to Group A, and spinal anesthesia was provided to Group B. The participants' demographic data, hospital stays, operating times, stone removal rates, and intra- and post-operative problems were all recorded. Data on intraoperative parameters, stone clearance, and postoperative complications were collected and analysed using SPSS 23.0. Results: General anesthesia significantly reduced the dilatation time (104.01 ± 12.772 vs. 130.552 ± 22.532 sec, p < 0.001) and time to reach the stone (126.68 ± 12.592 vs. 137.602 ± 17.841 sec, p < 0.001) compared to spinal anesthesia. However, no significant differences were observed in lithotripsy time, operation time, stone-free rates, or postoperative complications between the two groups. Patients in the GA group reported higher VAS scores and an increased frequency of nausea/vomiting after surgery. Conclusion: General anesthesia reduced the time for dilatation and stone access but showed no significant advantages in lithotripsy time, operation time, stone-free rates, or complications.
Prevalence of the Modifiable Risk Factors of Cardiovascular Diseases in Young Adults of District Hyderabad Sindh Pakistan
Authors: Shaikh Shakil Ahmed , Memon Salma Farukh , Shah Hanozia , Rahu Hajira Naila , Laghari Keenjher Rani , Shaikh Saima Naz , Laghari Zulfiqar Ali , Warsi Jamshed
Published: February 2025

Cardiovascular diseases are the major cause of morbidity and mortality around the world. Numerous studies concluded that populations of the subcontinent are more prone to develop cardiovascular diseases including Pakistan as compared to other countries. Objective: To determine cardiovascular disease risk factors in the healthy population of the Hyderabad district, Sindh. Methods: The cross-sectional study was conducted from July 2023 to December 2023, in this study, apparently healthy young adults of not more than 40 years of age were included. A self-designed questionnaire was set for the collection of data. Blood pressure was taken using the standard method, a mercury sphygmomanometer. South Asian standards calculated BMI, and the blood sample was taken after 10 hours of fasting for lipid profile and fasting blood sugar. Collected data were analyzed by SPSS version 23.0. Results: In this study, one risk factor was found in 276 (76%) of the participants, and Obesity was found in 41 (17%) and 66 (52%) respectively in group I and group II participants. Central obesity was found to be higher in group II 92 (72%) than in group I 69 (29%). Group II participants were found to have higher blood pressure than group I 61 (48%) and 61 (26%) respectively. Conclusions: It was concluded that 3 risk factors were found higher in females, and 4 risk factors were found higher in males, thus making the male population more prone to be affected by cardiovascular diseases even at an early age.
The Frequency of Blood Transfusion Reactions: A Retrospective Study from a Tertiary Care Hospital
Authors: Chohan Uzma , Najam Sumayya , Rajput Khushbakhat Khanzada , Rajput Maryam Khanzada , Waqar Syeda Azka , Yunus Namra
Published: February 2025

Blood Transfusion Reactions (BTRs) are complications that may occur during or after transfusion, in which allergic reactions and Febrile Non-Hemolytic Transfusion Reactions (FNHTRs) being the most common. Objective: To assess the frequency and types of transfusion reactions among patients at Shahida Islam Medical College Hospital and a blood transfusion service supplier. Methods: This study analyzed transfusion reactions reported between January, 2022, and September, 2024.  A total 1936 transfused has done during this time frame.  Data were collected using non-probability convenience sampling, covering patient demographics, blood products used, and Incident rate of transfusion reactions. IBM SPSS version 28.0 was utilized for statistical analysis, with categorical variables presented as frequencies and percentages. Results: Out of 1936 transfusions a total 12 (0.6%) reported transfusion reactions in which allergic reactions accounted for the majority (50.0%), followed by FNHTRs (33.33%) and none or very limited reactions of other reactions seen both on whole blood and PCV. The overall incidence of transfusion reactions was 0.53%. Conclusions: This study highlighted that allergic reactions are the most prevalent Blood Transfusion Reactions, emphasizing the need for premedication protocols for high-risk patients. Future research should focus on identifying predictive markers for allergic reactions, refining transfusion protocols.
Sample Code of Ethics for an International Scientific Society in Informatics
Authors: Markov Krassimir , Ivanova Krasimira
Published: February 2025

The Sample Code of Ethics encapsulates collective commitment to principles of integrity, ethical responsibility, and professional conduct within the expansive domain of information science. It serves as a guiding framework, illuminating the path toward a harmonious, transparent, and respectful community. By embracing these ethical standards, society members contribute to the elevation of knowledge and the enrichment of collaborative endeavors. This Code stands as a testament to dedication to fostering an environment where ethical considerations are paramount, ensuring that work positively impacts society and the broader tapestry of human understanding.
Genetic characterization of LEP and TG5 gene polymorphisms in crossbred beef cattle populations
Authors: Dung Dinh , Huong Duong , Tra Than , Hang Le , Phung Le , Van Nguyen , Chau Ho
Published: February 2025

Objective: This study aimed to investigate the single nucleotide polymorphisms (SNPs) in the intron 2 region of the leptin (LEP) gene and the 5’ untranslated region of the thyroglobulin (TG5) gene across four crossbred beef cattle populations, including Blanc Bleu Belge × Lai Brahman (BLB), Charolais × Lai Brahman (CLB), Droughtmaster × Lai Brahman (DLB), and Red Angus × Lai Brahman (RLB) raised in Central Vietnam.
Materials and Methods: A total of 200 tail hair root samples (50 per group) were collected, and genomic DNA was extracted. The PCR-RFLP method was utilized to analyze the LEP and TG5 gene polymorphisms using the restriction enzymes Sau3AI and PsuI, respectively.
Results: The SNPs of LEP/Sau3AI and TG5/PsuI were present in all populations, with a lower frequency of the LEPB allele compared to LEPA. The LEPAA genotype was most common, followed by LEPAB and LEPBB; notably, the LEPBB genotype was absent in the CLB group. The Hardy–Weinberg equilibrium was observed for LEP/Sau3AI in the CLB and BLB populations. Conversely, the TG5CT genotype dominated all groups, with no individuals exhibiting the TG5TT genotype. None of the populations achieved Hardy–Weinberg equilibrium for TG5/PsuI. The level of polymorphism was moderate for LEP/Sau3AI in RLB and BLB and for TG5/PsuI across all groups.
Conclusion: The SNPs of LEP/Sau3AI and TG5/PsuI may serve as valuable tools for genomic selection. By focusing on increasing the frequency of the TG5T allele, breeding programs can more effectively enhance beef marbling and other important traits, leading to improved beef quality and greater economic outcomes in the cattle industry.
Phthalate plasticizer affects blood electrolytes, hormones, and reproductive parameters of black Bengal goats
Authors: Hasan Sajibul , Mustari Afrina , Rafiq Kazi , Miah Mohammad
Published: February 2025

Objective: The present study looked at how electrolytes, hormones, and postpartum reproductive physiology were affected in black Bengal goats (BBGs) when they were fed a phthalate mixture (PHA).
Materials and Methods: Twenty clinically healthy BBGs, 1–2 months pregnant, aged 6–8 months with a body weight of 10–12 kg, were chosen and randomly allocated to two experimental groups (n = 10 each). The BBGs of the treatment group (n = 10) were administered a standard ration containing a mixture of Diethyl Phthalate, Dibutyl Phthalate, Di-isobutyl Phthalate, and Dipropyl Phthalate. The non-treated control group (n = 10) received the goat ration without any phthalates up to parturition. Blood samples were taken from experimental pregnant goats just before parturition to analyze serum hormone and electrolyte levels.
Results: The levels of sodium, chloride, and calcium were reduced (p < 0.05) in PHA-exposed goats than in the non-exposed control group. No significant difference was observed in potassium and phosphorus levels between the two groups. PHA-exposed goats showed significantly decreased levels of estrogen, progesterone, luteinizing hormone, and thyroxin compared to control goats (p < 0.05). Postpartum reproductive traits, such as gestation length, postpartum heat period, abortion rate, and retained placenta, were significantly (p < 0.05) prolonged in BBG that had been exposed to PHA.
Conclusion: PHA plasticizer exposure during pregnancy affects the electrolytes, hormones, and postpartum reproductive physiology of BBGs.
Effect of melatonin, zinc sulfate, nano-melatonin, and nano-zinc oxide on mitochondria function and developmental competence of buffalo oocytes
Authors: Kandil Omaima , Elsehy Heba , Baker Nabil , Elbehiry Mohamed , Hattab Sayed
Published: February 2025

Objective: The aim of the current work is studying the effect of antioxidants and nano-antioxidants on in vitro development and mitochondrial function of buffalo oocytes.
Materials and Methods: Good and excellent Buffalo oocytes were in vitro matured: (1) tissue culture medium-199 (control group), (2) TCM-199 + melatonin (Mel) 10−9 M (Mel group), (3) TCM-199 + zinc 10−6 M (Zn group), (4) TCM-199 + nano- Mel 10−6 M (N-Mel group), and (5) TCM-199 + nano-zinc-oxide 10−6 M (N-ZnO group) and incubated with CO2 5% and 38.5°C for 22 hr. In vitro-matured oocytes were either stained for mitochondrial function or cultured for detection of embryo development.
Results: The maturation rate of buffalo oocytes in the N-Mel and N-ZnO groups had a significant (p < 0.05) increase (91.89% and 93.64%, respectively) compared to the Mel group (85.78%) and Zn group (81.37%), and all groups were significantly higher than the control (73.16%). Mitochondrial intensity was significantly elevated (p < 0.05) in the N-Mel and N-ZnO groups than in oocytes matured in the Mel, Zn, or control groups. Rates of fertilization, cleavage, and transferable embryos of buffalo oocytes matured in vitro were significantly raised in the N-ZnO group (88.35%, 85.93%, and 30.71%, respectively) and the N-Mel group (86.74%, 82.75%, and 28.32%, respectively) (p < 0.05) when compared with the Mel group (82.46%, 77.25%, and 21.29%, respectively) and the Zn group (79.98%, 75.19%, and 19.68%, respectively), and all were increased significantly (p < 0.05) compared to the control group (71.76%, 68.7%, and 11.98%, respectively).
Conclusion: Supplementation of maturation medium with Mel 10−9 M and zinc sulfate 10−6 M and nano-Mel 10−6 M and nano-zinc oxide 10−6 M improves buffalo oocyte maturation rates, mitochondrial function, and embryo development.
Effect of narrowband ultraviolet B (311 nm) exposure on skin carcinogenesis in Wistar rats
Authors: Krisanti Roro , Wanandi Septelia , Wuyung Puspita , Hoemardani Aida
Published: February 2025

Objective: The aim of this study is to determine narrowband UVB (NB-UVB) irradiation’s effect on the promotion of skin cancer, particularly its effect on DNA damage, oxidative stress, inflammation, and histological changes in Wistar rat skin.
Materials and Methods: Wistar rats were selected for this study and randomly divided into control, dimethylbenzanthracene (DMBA), and DMBA+NB-UVB groups. The rats were given a single dose of DMBA and exposed to NB-UVB 3 times a week for 10 weeks. The radiation dose started with 1 minimal erythema dose, which is equivalent to 3.192 J/cm². In the 11th week, analysis on cyclobutene pyrimidine dimer (CPD), malondialdehyde (MDA), nuclear factor kappa-B (NFκB), inflammatory cytokines, and histopathology examination of the skin tissue was conducted.
Results: Higher CPD, MDA, NFκB, tumor necrosis factor a (TNF-a), interleukin (IL)-6, IL-11, IL-10, and IL-12 levels in rats exposed to DMBA+NB-UVB for 10 weeks compared to control and DMBA groups. Macroscopic examination presented erythema, skin thickening, desquamation, ulcer, and crust. Histopathology examination showed hyperkeratosis, acanthosis, atypical keratinocytes,irregular arrangement of the basement membrane, and inflammatory cell infiltration in the DMBA+NB-UVB group.
Conclusion: This research has shown that 10 weeks of a combination of DMBA and NB-UVB irradiation induced DNA damage, oxidative stress, inflammation, and histological changes in the Wistar rat skin.
Efficacy of niclosamide and ivermectin suspension preparations in sheep parasitoses
Authors: Marchenko Victor , Vasilenko Yury , Biryukov Ivan , Khalikov Marat , Khalikov Salavat , Sazmand Alireza
Published: February 2025

Objective: This study aimed to examine the efficiency of newly formulated drugs based on mech¬anochemical modification of two widely used anthelmintic substances in suspension formulations against the main classes of helminths and parasitic arthropods.
Materials and Methods: Solid-phase co-grinding of two substances, i.e., ivermectin (IM) and niclosamide (NS), with licorice extract and sodium succinate was performed in liquid-phase processing to obtain suspension formulations. Drug preparations were administered to the sheep of the experimental groups (5 experimental groups of 8 heads) with different concentrations of active substances, i.e., 3.0, 5.0, and 10.0 mg/kg of body weight (BW) NS and 0.2-mg/kg BW IM. Aqueous suspensions of the original substances in dosages of 0.2-mg/kg BW IM, 10.0-mg/kg NS, and placebo were included as controls. Efficacy of the formulations against gastrointestinal stron¬gyles, Trichuris spp., Moniezia spp., and nasal bot larvae (Oestrus ovis) was assessed in naturally infected sheep by the number of surviving adult parasites post-treatment in the gastrointestinal tract, nasal passages, and sinuses.
Results: Formulated suspensions showed an increased solubility of 5.5–13.1 times compared to the original substances. Treatment of sheep with the SusIN-10 drug containing 0.2-mg/kg BW IM and 10.0-mg/kg NS showed 100% efficiency against gastrointestinal strongyles, Moniezia, and nasal bot larvae. Formulations containing 0.2-mg/kg BW IM and 3.0- and 0.5-mg/kg NS could eliminate all of the Trichuris worms. Administration of original substances of IM and NS with rec¬ommended dosages did not result in the adult parasites’ complete elimination.
Conclusion: Modification of the anthelmintic substances through mechanochemical methods made it possible to create formulations with a targeted spectrum of action, significantly higher water solubility, and optimal parasiticidal activity.
Orbital Manifestations of Hodgkin Lymphoma in a Pediatric Patient: a Case Report
Authors: Gabric Ivana , Bakrac Ana , Jagic Mateja , Biscevic Alma
Published: February 2025

Background: Hodgkin lymphoma (HL) is primarily characterized by the presence of Reed-Sternberg cells and predominantly affects the lymph nodes. However, it can also manifest in extranodal sites, including rare instances of orbital involvement. Objective: This report aims to present atypical symptoms associated with HL and its orbital manifestations in a pediatric patient. Case report: To discuss the clinical presentation, diagnostic journey, and management of a 4-year-old boy who exhibited orbital manifestations of HL. Initially, he was misdiagnosed as having an infectious process due to symptoms such as ptosis (drooping eyelids) and eyelid edema (swelling). Consequently, the patient received inappropriate treatments that delayed the correct diagnosis. This case highlights the challenges posed by atypical presentations in pediatric patients and underscores the importance of considering malignancy in the differential diagnosis. It also emphasizes the necessity of a multidisciplinary approach to achieve accurate and timely diagnosis and treatment. Conclusion: Through this case, we aim to enhance the understanding of orbital manifestations of HL and emphasize the need for increased awareness among clinicians when encountering unusual orbital findings in children.
Effect of Mono Metal Doping of ZnWO4 Nanoparticles with Sodium, Magnesium and Titanium
Authors: Abubakar Hassana , Dawi Hadiza , Odimba Chinomso
Published: February 2025

Sol-gel synthesized Zinc Tungstate Nanoparticles (ZnWO4) were subjected to metal doping using sodium, magnesium and titanium. This research involved the utilization of the wet impregnation method as well as variation of the concentration of each dopant ions at 1%, 3%, 5% and 7% respectively. The resulting nanocomposite materials were characterized using HRTEM, SAED and XRD spectroscopy, and according to the results obtained, regardless of the concentration, results obtained revealed the presence of bright spots and lattice fringes which clearly indicate relatively high crystallinity for the Na, Mg and Ti doped ZnWO4 nanocomposites, which corroborates with the XRD patterns for each nanocomposite material. According to XRD analysis, ZnWO4 nanoparticles formed were highly crystalline, monoclinic in phase with a reduced crystallite size in all the samples analysed. The results of the characterization revealed that doping was successful at improving the efficiency of the synthesized ZnWO4 nanoparticles. A major recommendation for this study is to test the efficiency of doping ZnWO4 with two or more metal ions at a time.
IMPACTS OF THE USE OF UNCERTIFIED
CONSTRUCTION PROJECT MANAGERS ON
THE SUCCESS OF CONSTRUCTION PROJECTS
IN NIGERIA.
Authors: Liman Abdulrauf , Obianyo Ifeyinwa , Kolo Musa
Published: February 2025

This study investigates the influence of certified and uncertified construction project
managers' impact on project success in the Nigerian construction sector, employing a
quantitative and descriptive research design. Utilizing statistical tools such as SPSS
and Microsoft Excel, data from 134 respondents underwent comprehensive analysis.
The research explores demographic profiles, knowledge, skills, competencies, and
project success criteria differences between certified and uncertified project managers.
Demographic findings highlight a gender imbalance, predominantly male
representation, and diverse age groups among project managers. Both certified and
uncertified managers exhibit a robust understanding of project management principles,
with certified managers showing a slightly higher proficiency. Certified project
managers self-report higher skills, especially in communication and interpersonal
areas. Evaluation of project success criteria, encompassing time, cost, quality, and
stakeholder satisfaction, reveals no significant differences between certified and
uncertified project managers. Barriers to project management standards adoption and
certification include resistance to change as the most critical factor. Recommendations
include enhancing education and training, promoting certification, strengthening
regulatory frameworks, creating incentives for compliance, facilitating industry
collaboration, and improving access to finance and infrastructure. Future research
suggestions encompass in-depth analyses, longitudinal studies, industry-specific
comparisons, regional disparities, qualitative assessments, and global benchmarking.
This study contributes significant insights to both academia and industry, shedding
light on the intricate project management dynamics in Nigerian construction sector.
Review on Implementation of Automatic Packing Machine System based on PLC
Authors: Osanaiye Opeyemi , Ogedengbe Temitayo , Olamide Usman , Muhammad Ibrahim , Yusuf Al , Sambo Bashir
Published: February 2025

Commodity packaging machinery goods are diverse in the commodity business; the shape, nature, and packaging needs of the commodity are distinct, and the output is vast. Designing a commodity packaging machine control system should address the pressing demands of domestic commodities firms for all types of automatic packaging machines. Various efforts by researchers to automate packaging processes have been studied in this work. The study also reviewed the implementation of automatic packaging machines based on PLC. The automatic packaging machine framework was discussed and the procedures in the design of these machines have also been discussed. Finally, the gains and challenges of the implementation of this process have been enumerated. It is believed that a wide adaptation of this process for packaging processes will result in an improvement of overall efficiency of the packaging systems.
Case Study: Operational Processes of sensors.AFRICA in Developing Low-Cost IoT Sensors Across Africa
Authors: ahmed Usman , maina gideon , mwenda augustine , olago alicia
Published: February 2025

sensors.AFRICA develops low-cost sensors for monitoring air quality, noise levels, and gases, designed and produced through a globally distributed process. This case study explores the design, manufacturing, deployment, and maintenance processes managed by a small team of hardware and software engineers spread across multiple cities in Africa. With manufacturing activities spanning four continents, the initiative delivers real-time environmental monitoring solutions, empowering communities with actionable insights. The study highlights the iterative design process, the challenges faced in operations, and the team’s approach to fostering innovation and resilience in a hybrid work environment.
A cross-sectional study to assess nutrition knowledge, attitude, and practice among first year nursing undergraduates of KLE Institute of Nursing College Belagavi
Authors: M Sayli , Dandannavar Vijaya , Anand Nirmala , Angolkar Mubashir , M Bhagyashree , Goltekar Dhruv , Singh Yagya , Paloji Falaq
Published: February 2025

Background:
Nursing is a life sustaining profession for the health of community. Nursing students, generally between the age group of 17 and to 22 years, come in the category of adolescent and young adults. Nutritional status is affected by nutritional knowledge and habits.

Aim:
To determine Nutrition knowledge, attitude and practice among undergraduates of Nursing 1st year students from KLE Institute of Nursing college Belagavi.

Methods:
A cross-sectional study on assessment of nutritional knowledge, Attitude, and practice among first year nursing students from KLE institute of nursing collage Belagavi. The information on nutritional knowledge, attitude, and practice with demographic profile was collected using questionnaire. Both male and female students are participated in the study, informed consent was taken from the participants. Data was analyzed using chi square test.

Results:
Among 93 of nursing first year students, majority were females 60(65.2%). Students have average nutrition knowledge 41(44.6%) I.e. >Mean – SD to Mean + SD and almost students have same practice and attitude towards nutrition is also average 72(78.3%) >Mean – SD to Mean + SD.

Conclusion:
The present study concluded that most of the first-year nursing students from Institute of nursing college Belagavi had an average nutrition knowledge and all of them had same practices towards Nutrition & their attitude was average towards the same.
Exploration of Characteristic Equation Towards the Analysis of Dynamical Stability for Synchronous Generators through Swing Equation
Authors: Mohamad Murad Nor Syaza Farhana , Kamarudin Muhammad Nizam , Hanafi Ainain Nur , Md. Rozali Sahazati
Published: February 2025

This study reports a didactic approach on how to exploit the knowledge of the characteristic equations of any second-order system towards their stability analysis. To prove the efficacy of the method in industrial applications, the manuscript focuses on the stability study of synchronous generators. To obtain the future-ready characteristic equation, the dynamic equation of a synchronous generator is modeled via the swing equation. Literally, the swing equation describes the behavior of the rotor dynamics in the generator. By using the characteristic equation at hand, dominant parameters that affect the stability are identified. The analysis studies are then conducted to observe the stability through multifarious allowable parameters’ range that disturb the roots (or the poles) location of the equation. The outcome of this research shows that two dominant parameters, named synchronizing coefficient and per unit inertia constant, determine the damping ratio and natural frequency. As a result, these two parameters affect the stability and transient characteristics of synchronous generators.
L’homme et la machine
Authors: BELLOUR Raymond
Published: February 2025

J'ai choisi comme matériau d'expérience deux plans, dans le film Miss Oyu de Kenji Misoguchi, et un film très court, composé de six plans, du cinéaste expérimental américain Leighton Pierce.Dans les trois cas, j'ai remarqué des discordances flagrantes entre le relevé détaillé que j'ai pu faire des traits expressifs, qui m'ont semblé constitutifs de la matière comme des événements intérieurs aux plans considérés, et l'ensemble des remarques qui ont été formulées par les deux témoins, jaune et bleu. J'ai essayé de faire le relevé le plus soigneux possible de ces écarts, sans pouvoir comprendre ce qui avait motivé les choix, et surtout les non-choix de la machine, dans ses partis-pris et ses discriminations.
Réparation, reconstruction, réappropriation, restauration, restitution, reconstitution : pratiques et enjeux des interventions d’artistes contemporains dans les musées d’histoire et de société
Authors: GOUDINOUX Véronique
Published: February 2025

Cet article s’intéresse au choix de certain·es chargé·es de collections de musées d’histoire, de société et de civilisation d’inviter des artistes contemporain·es à réaliser dans leurs murs des œuvres, des expositions, des interventions à partir de leurs collections. Son objectif est de tenter de déterminer si, dans ces contextes précis, la question de la réparation, ou celles du réparable ou de l’irréparable, sont en jeu, et si oui, de quelle manière, cela en accordant une attention particulière aux termes dans lesquels ces questions sont formulées. L’article résulte du programme de recherche « Projets d’artistes / Projets de musées » du Centre d’étude des arts contemporains de l’Université de Lille (ULR – CEAC 3587), un programme qui met en œuvre une méthode qui repose sur l’écoute de descriptions, d’observations, d’analyses et de récits (tous différents, parfois divergents) émanant des différent·es acteur·es de tel ou tel musée ayant contribué au même projet (artistes, curateur·es, scientifiques, médiateur·es, etc.), l’idée étant de se déprendre d’interprétations déjà effectuées, de donner une place aux points de vue, voix et sujets rencontrés au cours de nos recherches et de permettre ainsi de percevoir la complexité des projets étudiés. L’accent est porté sur le travail considérable et aux multiples facettes réalisé depuis plus de deux décennies dans une institution, l’AfricaMuseum – Musée Royal d’Afrique Centrale (MRAC – Tervuren).
Quand l’irréparable hante le réparé : témoignages et archives traumatiques sur la scène théâtrale
Authors: FEVRE Lili
Published: February 2025

La scène théâtrale documentaire a placé en son cœur la question du traumatisme. La notion de traumatisme s’ancre dans une temporalité double, entre le vécu, l’immédiat du choc et sa représentation ou sa cicatrice. Depuis leur origine, avec Piscator, jusqu’à leur omniprésence sur la scène contemporaine, les théâtres documentaires semblent exister dans une visée plurielle : analyse, dénonciation et/ou réparation. Sur la scène contemporaine, la présence de témoins réels relève de l’évidence. Leur statut n’est pas remis en question. Comme les images de la Première Guerre mondiale projetées dans Malgré tout de Piscator, la présence de Yolande Mukagasana dans Rwanda 94 s’impose sans questionnement explicite ni remise en cause implicite. On n’interroge pas la capacité à témoigner. La présence de ces témoins s’inscrit pourtant dans des dispositifs scéniques particuliers qui sont aussi des dispositifs de pensée, avec une portée critique et plus largement politique. En s’appuyant sur les notions de représentation et d’irreprésentable, cet article cherche à mettre en lumière ce que la scène théâtrale permet de réparer et les limites de l’irréparable. La pluralité sémantique des termes plaçant au cœur de notre étude la définition des concepts et leur appréhension, entre le modèle juridique et le modèle psychologique, tels qu’ils sont établis par Johann Michel, et la recherche d’un modèle artistique, s’il existe.
Joséphine décapitée : les limites de la destruction des statues comme pratique culturelle de réparation et décolonisation
Authors: KOPF Martina
Published: February 2025

Joséphine de Beauharnais (1763-1814) est un personnage fortement contesté en Martinique. L’épouse de Napoléon, née sur l’île, est étroitement associée à l’histoire des colonies françaises, et par conséquent, à celle de l’esclavage. Construite durant les années 1850 par Vital Gabriel Dubray, la statue de Joséphine, sur la place de la Savane à Fort-de-France, est passée d’un simple objet de commémoration à un objet de dé-commémoration : tagguée à de nombreuses reprises, décapitée en 1991, la statue fut finalement retirée de l’espace public en 2020 par des activistes du mouvement Rouge-Vert-Noir – couleurs d’un drapeau de nationalistes martiniquais – pour la faire tomber entièrement. La pratique presque rituelle de la destruction se révèle être une pratique de réparation qui peut être considérée, non seulement comme une forme de décolonisation de l’espace public (Vergès), la pensée de la réparation étant une pensée de la décolonisation (Solbiac), mais aussi comme un événement qui restera dans la mémoire culturelle martiniquaise. Finalement, les possibilités et les limites de cette pratique de réparation (Bachir Diagne) seront discutées.
Art, féminisme, renaissance artistique
Authors: NERI Silvia
Published: February 2025

Cet article plonge au cœur des inspirations artistiques des artistes femmes qui s’investissent dans des tentatives d’autoréparation, mettant en lumière la manière dont les traumatismes collectifs sont examinés et retravaillés par le prisme de la création artistique. Ce texte scrute les connexions et tensions inhérentes entre la démarche de réparation artistique individuelle et celle orientée vers l’autre, soulignant la délicate interférence entre l’autotranscendance artistique et la construction de solidarités collectives. La sélection d’artistes féminines souligne l’importance de reconnaître et de mettre en avant la voie/voix créative des femmes dans un contexte artistique historiquement masculin. Ces artistes examinent des sujets profonds, reflétant la diversité des expériences féminines et contribuant à redéfinir les récits sociaux contemporains. Cette étude vise ainsi à enrichir la compréhension des liens entre l’art, la tentative de guérison personnelle et la construction de solidarités collectives dans notre société actuelle.