bluuebunny/crossref_metadata_2025 huggingface dataset:
PENGARUH MANFAAT, KEPERCAYAAN, DAN KEMUDAHAN PENGGUNAAN TERHADAP MINAT NASABAH MENGGUNAKAN LAYANAN MOBILE BANKING PADA PT. BANK PEMBANGUNAN DAERAH SUMATERA BARAT CABANG KOTO BARU, DHARMASRAYA
Authors: Fernos Jhon , Alfadino Mairizal
Published: July 2021

This research aims to test the effect of benefits, trust, and ease of use on customer interests using mobile banking services at PT. West Sumatra Regional Development Bank Koto Baru Branch, Dharmasraya. The variables used in this study are bound variables i.e. customer interest (Y), and free variables consist of benefits (X1), trust (X2), and ease of use (X3). The type of data used in this study is quantitative data. The accumulation of data used in this study was primary data from questionnaires and using teknik slovin. Technical data analysis using classic assumption test, multiple linear regression analysis, and t test. The population in this study was a customer of PT Bank Pembangunan Daerah Sumatera Barat Koto Baru Dharmasraya Branch, the sample in this study amounted to 148 respondents.The research data was collected from respondents' results and analyzed with liniear regression and hypothesis test. The results showed that the variable benefits did not have a positive and significant effect on customer interest with a t-count value of (1,138<1.665) dan untuk variabel kepercayaan berpengaruh positif dan signifikan terhadap minat nasabah dengan nilai t-hitung sebesar (25.426>1,655), furthermore for ease of use positive and significant effect on customer interest with a t-count value of (2,810>1,655).
PENGARUH LINGKUNGAN KERJA DAN BUDAYA ORGANISASI TERHADAP KINERJA PEGAWAI PADA BADAN KEUANGAN DAERAH PEMERINTAH PROVINSI SUMATERA BARAT
Authors: Zandria Alisna Almi , Fernos Jhon
Published: July 2021

This study aims to determine the effect of work environment and organizational culture on employee performance at the Regional Finance Board of the West Sumatra Provincial Government. The variables used in this study are the dependent variable, namely employee performance (Y), and the independent variable consisting of work environment (X1) and organizational culture (X2). The types of data used in this research are qualitative data and quantitative data. Accumulated data used in this study were primary data from questionnaires and used a proportional random sampling technique. The data analysis technique used classical assumption test, multiple linear regression analysis and t test. The population in this study were all employees of the regional financial agency of the province of West Sumatra, the sample in this study was 72 employees or respondents. The research data were collected from the respondents' results and analyzed using linear regression and hypothesis testing. The results of this study indicate that the work environment has a positive and significant effect on employee performance, with a t-count value of (3,342 > 2,000) and organizational culture has a positive effect on employee performance, with a t-count value of (3,336 > 2,000).
PENGARUH KUALITAS PELAYANAN, HARGA, DESAIN PRODUK, DAN CELEBRITY ENDORSER TERHADAP KEPUTUSAN PEMBELIAN PAKAIAN MAHASISWA PADA APLIKASI SHOPEE (STUDI KASUS MAHASISWA JURUSAN FARMASI UNIVERSITAS PERINTIS INDONESIA)
Authors: Anwar Syaiful , Aldiansyah Lubis Mhd
Published: July 2021

The growing internet today encourages companies to determine the right marketing strategy to survive and win the competition from its competitors. Like using the Shopee application as an e-commerce or online trade used in marketing products and services. The population in this study were students of the Department of Pharmacy, Universitas Perintis Indonesia TA. 2017-2020 as many as 659 students. The research sample was 87 students with sampling technique using non-probability sampling technique with purposive sampling technique or sampling technique with certain considerations. Data collection was carried out by distributing questionnaires while data processing used validity tests, reliability tests, multiple linear regression analysis and t tests using SPSS version 20. The results of this test prove that service quality, price, product design and celebrity endorsers have a positive and significant influence. to purchasing decisions.
Penyimpangan Nilai-Nilai Etika Dalam Berbusana Adat Ke Pura Di Desa Penarungan Kecamatan Mengwi Kabupaten Badung
Authors: Arista Jaya I Kadek , Perbowosari Heny , Sedana Suci I Gede
Published: July 2021

The development of global currents has an impact on various aspects of life, including community culture. One of them is in terms of clothing which is influenced by foreign cultures. This of course degrades ethical values ​​in the use of clothing, especially clothing used at social events or places of worship such as traditional clothing to temples. The influence of outside culture that is abused certainly causes deviations in ethical values ​​in the use of traditional clothing to the temple, one of the villages affected by the deviation is Penarungan Village. As a tourism destination, the people of Penarungan Village cannot turn a blind eye to outside culture, this causes deviations in ethical values ​​of traditional dress to the temple in Penarungan village. This research uses value theory, behaviorism, and social interaction. The approach used is ethnography. Informants were determined by purposive sampling. The research location chosen was Penarungan Village. Data collection techniques are by observation, interviews, and library techniques. The results of the study show that the forms of deviation from ethical values ​​in traditional attire to the temple in Penarungan Village include: (1) Deviations using kamen, (2) loose hair, (3) transparent and vulgar clothes, (4) T-shirts. the causes of deviations in values. Ethical factors in traditional kepura dress in Penarungan Village include (1) social media, (2) development of the times, (3) economic factors. The strategies of Hindu religious leaders in strengthening ethical values ​​in traditional attire to temples in Penungan Village (1) bring order to the people who violate them, (2) use uniform clothing.
Nilai-Nilai Pendidikan Karakter yang Terkandung di Dalam Ritual Bersamaan Hari Kemerdekan di Pura Pucak Desa Pelapuan Kecamatan Busungbiu Kabupaten Buleleng
Authors: Rai Semara I Dewa Made
Published: July 2021

The purpose of this study was to describe the values ​​of character education contained in the ritual along with Independence Day at Pucak Temple Pelapuan Village, Busungbiu District, Buleleng Regency. Character values ​​in the development of education are very important things to do in order to realize a better nation's civilization. At the same time, in order to strengthen the values ​​of the nation's character, it can be done in various ways in everyday life. The values ​​of the nation's character have actually been contained in almost every human behavior that lives in various regions throughout Indonesia. The most basic problem with regard to realizing the values ​​of the nation's character education is to identify them in a number of behaviors in social life. The results of research in ritual activities carried out at Pucak Temple Pelapuan Village, Busungbiu District, Buleleng Regency have shown an effort to realize the values ​​of the nation's character in relation to the implementation of Hinduism. Hindus who carry out these activities simultaneously carry out two types of activities that support each other. First, religious rituals carried out by Hindus as a form of worship to the great power who resides in the temple to ask for waranugraha in order to overcome the struggle of life. Second, Hindus who carry out religious rituals also carry out national ceremonies by singing the anthem Indonesia Raya, Menhening Cipta, and chanting Pekik Merdeka as a form of love for the Republic of Indonesia. The ritual process is associated with the theory of symbols as a form of appreciation of Hindu religious teachings using symbolic media. The implementation of these activities is associated with Value theory, which is a manifestation of the implementation of the values of the nation's character as formulated by experts.
Pendidikan Kesehatan Reproduksi pada Remaja
Authors: Permatasari Dian , Suprayitno Emdat
Published: July 2021

Background: Reproductive health has the concept that everyone can have a satisfying and safe and responsible sex life. Therefore,it is the right of every teenager to be informed and have acces to true,complete and honest reproductive and sexsual health. The main objective of reproductive  health is to provide comprehensive reproductive health services to individuals and their partners, especiallyto adolescents so that each individual is able to purpose is to undergo the reproductive process. Methods: The method used in this community service uses counseling or socialization directly to the target, namely teenagers. Its specific purpose is  to protect adolescents from the risk of early marrieage, unwanted pregnancy, abortion, Sexually Transmitted Infection (STIs), HIV/AIDS and sexual violence. Results: The results showed that health counseling on reproductive health for adolescents in Nambakor village, sumenep regency was going well and carried out according to the goals and teenagers were very enthusiastic about participating in the counseling and very benificial for adolescents and the community. Conclusion: Suggestions are expected to be additional information regarding the importance of promotive, preventive, curative efforts in this case the importance of knowledge of productive health.
The Functioning of The Hybrid Integrated Partially Solar-Vapor-Compression Fridge
Authors: Ali Al-Dabbas Mohammad Awwad
Published: July 2021

The main purpose of our research is to increase the utilization of solar thermal energy to supply a refrigerator with vapor compression and reduce the refrigeration power needed for cooling. Combined Hybrid Solar - the vapor- compression refrigerating unit has been built and operates under Mutah University's environment in Jordan. The systems were made up of a capillary tube, condenser, evaporator, and collector. The vapor-pressure refrigerator was incorporated with the classic water-solar system to minimize the compressor's duty and to reduce power consumption in heating the amount of water held in the pipe to be sent along the tube outside the evaporator. After that, it will be returned to the compressor, But at a lesser temperature, to minimize compressor workload and enhance cooling performance. Before the compressor was developed, a solar collector system had been created to maximize its temperature before reaching the compressor to improve C.O.P, and the difference in temperature was remarkable. The vapor-compression refrigerator unit was powered by many generators: solar collector that has been discharged, photovoltaic system, flat plate solar collector. Two groups of tests have been performed experimentally on the partial solar compression refrigerator integrated into a hybrid system. First in the vapor compression refrigerator only, and the second in the Hybrid solar compression refrigerator incorporated. Total sunlight and different temperatures, current, and voltage were measured for many months each hour of the day. The performance coefficient was determined found 2.019, 2.432 respectively. Many auxiliary instruments are utilized to measure the temperature in irradiation networks, voltage, and night-time current every hour.
Justicia digital, acceso a internet y protección de datos personales
Authors:   Universidad de Medellín, Bustamante Rúa Mónica María , Marín Tapiero Jorge Iván ,   Universidad de Medellín
Published: July 2021

En este artículo se analiza el concepto de justicia digital, diferenciándolo de nociones similares como justicia electrónica, e-justice o justicia abierta. Además, se examina el principio de publicidad del proceso y el derecho de acceso al internet desde una perspectiva internacional. Posteriormente, se abordan de forma sucinta las Reglas de Heredia del 9 de julio de 2003, adoptadas como pautas mínimas para la difusión de información judicial en internet. Concluimos con los retos que representa la digitalización de la justicia y las alternativas para garantizar un umbral de mínimo respeto por los derechos de los administrados.
ASPECTE CLINICE ŞI TERAPEUTICE ÎN MALFORMAŢIILE CARDIACE DUCTO-DEPENDENTE (PARTEA A II-A)
Authors:   Secţia Clinică de Cardiologie Pediatrică, Spitalul Clinic de Urgenţe pentru Copii „Sf. Maria“, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Luca Alina-Costina , Holoc Andreea-Simona ,   Secţia Clinică de Cardiologie Pediatrică, Spitalul Clinic de Urgenţe pentru Copii „Sf. Maria“, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Subotnicu Mirabela ,   Secţia Clinică de Cardiologie Pediatrică, Spitalul Clinic de Urgenţe pentru Copii „Sf. Maria“, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Iordache Constantin ,   Secţia Clinică de Cardiologie Pediatrică, Spitalul Clinic de Urgenţe pentru Copii „Sf. Maria“, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi
Published: July 2021

Malformaţiile congenitale de cord cu circulaţie pulmonară ducto-dependentă sunt cardiopatii cu manifestări severe neonatale şi degradare hemodinamică rapid progresivă. Simptomatologia evidentă de la naştere necesită un diagnostic corespunzător şi management terapeutic precoce prin menţinerea permeabilităţii canalului arterial.
GASTRITELE ŞI HELICOBACTER PYLORI LA COPIL – DIAGNOSTICUL ENDOSCOPIC PRIMAR ŞI SECUNDAR
Authors:   Disciplina de Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Lupu V.V. , Păduraru Gabriela ,   Disciplina de Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Ignat Ancuţa ,   Disciplina de Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Tighici-Saizu Eliza ,   Spitalul Judeţean de Urgenţă, Vaslui, Olaru Claudia ,   Disciplina de Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Gimiga Nicoleta ,   Disciplina de Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Marin Angelica Cristina ,   Disciplina de Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Săvescu Cornelia ,   Disciplina de Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Florea Ioana ,   Disciplina de Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Burlea Marin ,   Disciplina de Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi
Published: July 2021

Infecţia cu Helicobacter pylori (H. pylori) este o problemă comună şi semnificativă de sănătate publică. Obiectiv. Determinarea prevalenţei infecţiei cu H. pylori la copiii cu simptomatologie sugestivă şi conturarea cazurilor în funcţie de tipul şi felul gastritei prin efectuarea de endoscopii digestive superioare. Material şi metodă. Studiu retrospectiv realizat pe o perioadă de 5 ani pe 1.269 de copii cu simptomatologie gastrică, la care s-au efectuat endoscopii cu biopsie, stabilindu-se rata de infecţie cu H. pylori prin examen direct sau testul ureazei. Rezultate. Frecvenţa H. pylori în cazul gastritei acute a fost semnificativ mai mică (34,78%) comparativ cu frecvenţa acesteia în cazul gastritei cronice (54,94%). În cadrul celor 10 tipuri de gastrită, cele mai frecvente sunt formele purpurice (43,66%), nodular purpurică (25,93%) şi nodular antrală (15,84%), la polul opus situându-se gastrita atrofi că şi hipertrofică. Asocierile cele mai frecvente decelate endoscopic sunt cu esofagita gr I în 51,6%, duodenita în 45,07% şi forma purpurică în 24,74%. Concluzii. Infecţia cu H. pylori este cel mai frecvent asociată gastritei cronice (54,94%). Identificarea precoce a infecţiei este esenţială pentru eradicarea bacteriei şi prevenirea apariţiei diferitelor tipuri de gastrită identifi cate endoscopic.
CLINIC AND THERAPEUTIC ASPECTS IN DUCTUS-DEPENDENT CONGENITAL HEART DEFECTS (PART II)
Authors:   Clinical Section of Pediatric Cardiology, “Sf. Maria” Emergency Clinical Hospital for Children, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Luca Alina-Costina , Holoc Andreea-Simona ,   Clinical Section of Pediatric Cardiology, “Sf. Maria” Emergency Clinical Hospital for Children, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Subotnicu Mirabela ,   Clinical Section of Pediatric Cardiology, “Sf. Maria” Emergency Clinical Hospital for Children, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Iordache Constantin ,   Clinical Section of Pediatric Cardiology, “Sf. Maria” Emergency Clinical Hospital for Children, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi
Published: July 2021

The cardiac congenital malformations with duct dependent pulmonary circulation are cardiopathies with severe neonatal manifestations and quickly progressive hemodynamic degradation. The obvious semeiology at the birth requires an appropriate diagnostic and an early therapeutic management through the maintenance of the arterial channel permeability.
INGESTIA CONCOMITENTĂ DE ETILENGLICOL ŞI ETANOL: O CAPCANĂ DE DIAGNOSTIC?
Authors:   Disciplina de Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Frăsinariu Otilia-Elena ,   Spitalul Clinic de Urgenţă pentru Copii „Sf. Maria“, Iaşi, Rugină Aniela ,   Disciplina de Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi,   Spitalul Clinic de Urgenţă pentru Copii „Sf. Maria“, Iaşi, Jităreanu Cristina ,   Spitalul Clinic de Urgenţă pentru Copii „Sf. Maria“, Iaşi, Russu Radu ,   Spitalul Clinic de Urgenţă pentru Copii „Sf. Maria“, Iaşi, Nistor Nicolai ,   Disciplina de Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi,   Spitalul Clinic de Urgenţă pentru Copii „Sf. Maria“, Iaşi, Ştreangă Violeta ,   Disciplina de Pediatrie, Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi,   Spitalul Clinic de Urgenţă pentru Copii „Sf. Maria“, Iaşi
Published: July 2021

Etilenglicolul este unul dintre cei mai toxici alcooli, fiind consumat accidental sau voluntar, ca substituent al etanolului sau în scop suicid. Ingestia de etilenglicol determină, prin metaboliţii săi toxici, acidoză metabolică severă, cu creşterea hiatusului anionic şi osmotic, conducând la un tablou clinic ce asociază deprimarea sistemului nervos central, afectare cardiovasculară şi insuficienţă renală. Prezentăm cazul unui pacient în vârstă de 16 ani internat pentru semne clinice şi biologice de intoxicaţie cu etilenglicol apărute după ingestia simultană de antigel şi alcool. Pacientul a prezentat acidoză metabolică doar la debut, rapid corectată de o doză de bicarbonat de sodiu; investigaţiile ulterioare nu au relevat acidoză, chiar dacă în evoluţie a apărut insuficienţa renală acută ce a necesitat hemodializă. Datorită absenţei anamnezei pozitive şi a acidozei metabolice persistente, diagnosticul de intoxicaţie cu etilenglicol a fost întârziat până la confirmarea prin testul toxicologic seric. Concluzii: ingestia concomitentă de etanol poate masca simptomele intoxicaţiei cu etilenglicol; absenţa acidozei metabolice persistente nu exclude diagnosticul.
TUBERCULOSTATICS ACUTE POISONING: DIAGNOSTIC AND TREATMENT
Authors:   “Grigore Alexandrescu” Emergency Hospital for Children, Bucharest, Boghitoiu Dora Andreea ,   Paediatrics Specialty, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Ulmeanu Coriolan Emil ,   “Grigore Alexandrescu” Emergency Hospital for Children, Bucharest,   Paediatrics Specialty, “Carol Davila” University of Medicine and Pharmacy, Bucharest
Published: July 2021

Introduction. Although the frequency of isoniazid poisoning is not very high, there are life threatening conditions which require a swift diagnosis and treatment. Material and method. We present the case of a female patient, aged 15 admitted in our clinic, by means of transfer, from another medical unit, due to tonic-clonic generalized seizures, followed by emesis and coma. The patient arrived at the Emergency Admissions Unit of our hospital, in coma, Glasgow 8, orotracheally intubated. She did not respond to verbal stimuli, but she did respond to deep, painful stimuli with marked agitation. The patient has a nasogastric tube, on which an orange liquid is visible on the outside and on the urinary catheter – orange colored urine. From the patient’s medical history, which was obtained from the patient’s mother, we noticed that the patient had been, for the past 4 months, under treatment with tuberculostatic drugs (Isoniazid, Rifampicin and vitamin B6). The patient administered the medication herself. Results. Based on clinical manifestations, i.e. tonic-clonic generalized seizures, incoercible emesis and coma, reddish-orange color of the gastric fluid and urine, at over 6 hours after the onset, on the patient’s medical history and based on laboratory results which revealed metabolic acidosis the suspicion of acute tuberculo-static poisoning arose. We started antidotal therapy with vitamin B6 with favorable clinical evolution. Conclusion. Acute isoniazid poisoning must be suspected in the case of any patient who presents the classic triad: refractory seizures, severe metabolic acidosis and coma and the treatment with the specific antidote-pyridoxine, must be available at any emergency unit.
CLINICAL AND THERAPEUTIC ASPECTS IN THE SEVERE AORTIC COARCTATION WITH DUCT DEPENDENT SYSTEMIC CIRCULATION IN THE NEWBORN
Authors:   Clinical Section of Pediatric Cardiology, “Sf. Maria” Emergency Clinical Hospital for Children, Iasi, Luca Alina-Costina ,   “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Holoc Andreea-Simona ,   “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Iordache Constantin ,   “Gr. T. Popa” University of Medicine and Pharmacy, Iasi
Published: July 2021

The aortic coarctation has an incidence of 0.6-0.8/1,000 newborn, with clinical manifestation starting with the neonatal period. In the newborn, the heart congenital malformations associated to heart failure and clinical response early in the first hours of life have a guarded prognosis, needing an early diagnostic and an adequate therapeutic conduct. We present a clinical case of severe aortic coarctation with duct dependent systemic circulation, diagnosed early in the neonatal period. The early treatment with Prostaglandin E1 allowed the maintenance of the hemodynamic balance, the newborn benefiting from surgical correction in the first month of life.
DRUG INDUCED ACUTE TUBULAR NECROSIS – RARE CASE OF NEPHROTIC SYNDROME
Authors:   “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Starcea Magdalena ,   Department of Pediatric Nephrology, “Sf. Maria” Emergency Clinical Hospital for Children, Iasi, Munteanu Mihaela ,   Department of Pediatric Nephrology, “Sf. Maria” Emergency Clinical Hospital for Children, Iasi, Russu Radu ,   Department of Pediatric Nephrology, “Sf. Maria” Emergency Clinical Hospital for Children, Iasi, Rotaru Anca Iulia ,   Department of Pediatric Nephrology, “Sf. Maria” Emergency Clinical Hospital for Children, Iasi, Mihaila Doina ,   Laboratory of Pathology, “Sf. Maria” Emergency Clinical Hospital for Children, Iasi, Miron Ingrith ,   “Gr. T. Popa” University of Medicine and Pharmacy, Iasi,   Department of Pediatric Nephrology, “Sf. Maria” Emergency Clinical Hospital for Children, Iasi
Published: July 2021

We presented two cases of nephrotic syndrome (NS) drug-induced with tubular nephrotoxicity, with different evolution in the context of etiologic diseases. First is 5-month-old girl admitted with NS (clinically and biological proven) and acute renal failure after another hospitalization for pneumonia. The girl was treated with ceftriaxone and gentamicin 12 days. Congenital NS suspicion was eliminated by renal biopsy who revealed renal tubular necrosis highlighting recovery phase. The development was favorable in 7 days of peritoneal dialysis. The second case was 16 years old adolescents treated 3 years with carbimazol for Basedow disease. Was presented with nephrotic syndrome not influenced by corticosteroids. Histopathology revealed toxic tubular necrosis, interstitial fibrosis, absence of glomerular injury. Nephrotoxic treatment was stopped, and, after thyroidectomy, edema were reduced, but kidney function continued to depreciate, while nephrotoxic therapy given for 3 years. Conclusions. Renal tubular necrosis clinical and laboratory expressed by nephrotic syndrome, accompanied by renal insufficiency is a rare occurrence in children; gentamicin and carbimazol can be criminalized. The suffering or impairment may be improved by removing the causative drug. Treatment failure was associated with duration of drug aggression and evolution of comorbidities.
POLYMORPHISM OF THE CLINICAL SIGNS OF CELIAC DISEASE IN CHILDREN
Authors:   3rd Clinic of Pediatrics, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Trandafir Laura Mihaela , Cirdeiu Eugen ,   3rd Clinic of Pediatrics, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Oltean Carmen ,   3rd Clinic of Pediatrics, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi, Mihaila Doina ,   Laboratory of Pathology, “Sf. Maria” Emergency Clinical Hospital for Childern, Iasi, Anton-Paduraru Dana-Teodora ,   3rd Clinic of Pediatrics, “Gr. T. Popa” University of Medicine and Pharmacy, Iasi
Published: July 2021

Celiac disease (CD) is an autoimmune systemic condition caused by sensitivity to gluten in genetically predisposed patients. The clinical signs of CD are extremely diverse, ranging from the typical intestinal malabsorption syndrome (characterized by chronic diarrhea, abdominal distension and malnutrition) to atypical symptoms that may involve any system or organ: chronic constipation, increased level of liver enzymes, iron deficiency anemia, recurrent abdominal pain, neurological conditions, tooth enamel erosion. The authors report four pediatric cases diagnosed with various atypical forms of celiac disease: the form associated with recurrent abdominal pain and increased level of liver enzymes, and the form associated with chronic constipation, all accompanied by failure to thrive and one case of type I diabetes mellitus associated with celiac disease. To conclude with, pediatricians, gastroenterologists and general practitioners should be familiar with all the clinical forms of coeliac disease in order to be able to diagnose this childhood disease and thus prevent long-term complications like osteoporosis, infertility and intestinal lymphoma.
CONSTIPAŢIA CRONICĂ LA COPIL. ACTUALITĂŢI ÎN EVALUARE ŞI MANAGEMENT
Authors:   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti, Galoş Felicia ,   Spitalul Clinic de Urgenţă pentru Copii „Maria Sklodowska Curie“, Bucureşti, Stoicescu Mihai ,   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti,   Spitalul Clinic de Urgenţă pentru Copii „Maria Sklodowska Curie“, Bucureşti, Munteanu Mihai ,   Spitalul Clinic de Urgenţă pentru Copii „Maria Sklodowska Curie“, Bucureşti, Năstase Gabriela ,   Spitalul Clinic de Urgenţă pentru Copii „Maria Sklodowska Curie“, Bucureşti, Anghel Mălina ,   Spitalul Clinic de Urgenţă pentru Copii „Maria Sklodowska Curie“, Bucureşti, Bălgrădean Mihaela ,   Universitatea de Medicină şi Farmacie „Carol Davila“, Bucureşti,   Spitalul Clinic de Urgenţă pentru Copii „Maria Sklodowska Curie“, Bucureşti
Published: July 2021

Constipaţia este un fenomen comun în practica pediatrică. Prevalenţa sa este în creştere, fiind prezentă, conform diferitelor statistici, la 0,7-29,6% dintre copii. Constipaţia este întâlnită la toate grupele de vârstă, cu severitate şi durată variabile, de la forme uşoare şi de scurtă durată la forme severe şi de lungă durată, cu impactare fecală şi in continenţă fecală. Acest articol revede aspectele epidemiologice, clinice şi terapeutice ale constipaţiei la copil, funcţionale în majoritatea cazurilor.
PATTERN-URI CLINICO-DEMOGRAFICE ALE DEPRESIEI ŞI ANXIETĂŢII LA COPII ŞI ADOLESCENŢI
Authors:   Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Ciubară Anamaria , Chiriţă Roxana ,   Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Burlea Ştefan Lucian ,   Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Ignat Ancuţa ,   Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Diaconescu Smaranda ,   Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Untu Ilinca ,   Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Lupu Valeriu V. ,   Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi
Published: July 2021

Atât la adulţi cât şi în cazul populaţiei pediatrice, depresia constituie o cauză majoră de dizabilitate, suicidul fiind a treia cauză de deces în rândul copiilor şi adolescenţilor. Cu toate că depresia şi depresia asociată cu anxietate sunt unele dintre cele mai frecvente patologii psihiatrice în rândul copiilor şi adolescenţilor, având un impact puternic asupra funcţionalităţii globale a acestora şi punând o amprentă remarcabilă asupra procesului lor de dezvoltare, rămân un domeniu insuficient explorat. Studiul de faţă îşi propune evidenţierea unor pattern-uri demografice şi clinice asociate depresiei şi anxietăţii la copii şi adolescenţi, care pot constitui premise pentru cercetări viitoare mai ample, dar şi pentru consolidarea unor metode de prevenţie primară, secundară şi terţiară.
NECROZA TUBULARĂ ACUTĂ PRIN ACŢIUNEA NEFROTOXICĂ MEDICAMENTOASĂ – CAUZĂ RARĂ DE SINDROM NEFROTIC LA COPIL
Authors:   Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi, Stârcea Magdalena ,   Secţia de Nefrologie Pediatrică, Spitalul Clinic de Urgenţă pentru Copii „Sf. Maria“, Iaşi, Munteanu Mihaela ,   Secţia de Nefrologie Pediatrică, Spitalul Clinic de Urgenţă pentru Copii „Sf. Maria“, Iaşi, Russu Radu ,   Secţia de Nefrologie Pediatrică, Spitalul Clinic de Urgenţă pentru Copii „Sf. Maria“, Iaşi, Rotaru Anca Iulia ,   Secţia de Nefrologie Pediatrică, Spitalul Clinic de Urgenţă pentru Copii „Sf. Maria“, Iaşi, Mihăilă Doina ,   Laboratorul de Anatomie Patologică, Spitalul Clinic de Urgenţă pentru Copii „Sf.Maria“, Iaşi, Miron Ingrith ,   Universitatea de Medicină şi Farmacie „Gr. T. Popa“, Iaşi,   Secţia de Nefrologie Pediatrică, Spitalul Clinic de Urgenţă pentru Copii „Sf. Maria“, Iaşi
Published: July 2021

Sunt prezentate două cazuri de sindrom nefrotic (SN) indus de medicamente cu nefrotoxicitate la nivel tubular, cu evoluţie diferită în contextul maladiilor incriminate etiologic. Fetiţă în vârstă de 5 luni, internată cu SN (dovedit clinic şi biologic) şi insuficienţă renală acută, după o spitalizare în alt servici pentru bronhopneumonie. Fetiţa a fost tratată cu ceftriaxonă şi gentamicină 12 zile. Suspiciunea de SN congenital a fost înlăturată de evidenţierea necrozei tubulare renale în fază de recuperare (biopsie renală). Evoluţia a fost favorabilă în 7 zile sub dializă peritoneală. Adolescentă de 16 ani cu boală Basedow tratată de 3 ani cu carbimazol. S-a prezentat cu sindrom nefrotic care nu a fost influenţat de corticoterapie. Examenul histopatologic a evidenţiat necroză tubulară toxică, fibroză interstiţială, absenţa leziunilor glomerulare. A fost sistat tratamentul nefrotoxic, s-a practicat tiroidectomie după care edemele s-au redus, dar funcţia renală a continuat să se deprecieze, în condiţiile terapiei nefrotoxice administrată timp de 3 ani. Concluzii. Necroza tubulară renală exprimată clinic şi biologic prin sindrom nefrotic, însoţit de insuficienţă renală este o situaţie rară la copil; gentamicina şi carbimazolul pot fi incriminate etiologic. Suferinţa renală poate fi ameliorată sau nu prin înlăturarea medicamentului cauzal. Eşecul terapeutic s-a corelat cu durata agresiunii medicamentoase şi evoluţia unor comorbidităţi.
Dipeptidyl Peptidase-4 Inhibitors and COVID-19-Related Deaths among Patients with Type 2 Diabetes Mellitus: A Meta-Analysis of Observational Studies
Authors: Patoulias Dimitrios , Doumas Michael
Published: July 2021

The coronavirus disease 2019 (COVID-19) pandemic remains an unbeaten enemy. Unfortunately, no targeted treatment option is available. Patients with type 2 diabetes mellitus (T2DM) have increased odds for severe or fatal disease, as demonstrated in recent observational studies. There is an ongoing discussion regarding the impact of different antidiabetic drug classes on outcomes of interest among affected subjects. Dipeptidyl peptidase-4 (DPP-4) inhibitors have been placed at the epicenter, since the DPP-4 enzyme seems to be implicated in the disease pathogenesis. Herein we present an updated meta-analysis of observational studies addressing the risk of COVID-19 death among patients with T2DM on prior DPP-4 inhibitor treatment. We pooled data from 10 observational studies, showing that DPP-4 inhibitors produce a non-significant decrease in the risk for COVID-19-related death. However, when administered in the inpatient setting, DPP-4 inhibitors decrease the risk for COVID-19-related death by 50%. Ongoing randomized controlled trials will shed further light.
Linear and nonlinear linkage of conditional stochastic volatility of interbank interest rates:
Empirical evidence of the BRICS countries
Authors: Dhifaoui Zouhaier , Gasmi Faicel
Published: July 2021

The purpose of this article is to detect a possible linear and nonlinear causal relationship between the conditional stochastic volatility of log return of interbank interest rates for the BRICS countries in the period from January 2015 to October 2018. To extract the volatility of the analyzed time series, we use a stochastic volatility model with moving average innovations. To test a causal relationship between the estimated stochastic volatilities, two steps are applied. First, we used the Granger causality test and a vector autoregressive model (VAR). Secondly, we applied the nonlinear Granger causality test to the raw data to explore a new nonlinear causal relationship between stochastic volatility time series, and also applied it to the residual of the VAR model to confirm the causality detected in the first step. This study demonstrates the existence of some unidirectional/bidirectional linear/nonlinear causal relationships between the studied stochastic volatility time series.
Implementation of the regulation on prescription for health insurance out-patients in Ninh Hoa Regional Hospital, 2019
Authors:   Hanoi University of Public Health, Nguyen Thi Thuy Nga , Le Quang Lenh
Published: July 2021

Objectives: The study assesses the current status of implementation of outpatient prescriptions and analyze some influencing factors at Ninh Hoa Regional General Hospital in 2019. Results: The results show that: 94, 75% of the prescription are safe; 29.75% prescription with 1 to 2 antibiotics; The average number of drugs in 1 prescription is 3.7 ± 1.24 medicines; The percentage of prescriptions with general drug interaction is 5.25%. There is no fourth level drug interaction. Some influencing factors are: Doctors do not pay adequate attention to safe and rational prescription. The bidding for drugs, the provision and supply of drugs are still delayed in time for medical examination and treatment. Hospitals do not have software for searching drug information and drug interactions Conclusion: Doctors should regularly update the drug information, comply with the prescription regulations, and avoid interactions when prescribing. The pharmacy department should advise the hospital director to sign a close contract with the pharmaceutical companies to supply drugs to patients fully and promptly. Key words: prescription, Regulation on Prescription, Health Insurance, Outpatient
Satisfaction of inpatient with diagnosis and treatment service and some associated factors in Hoan My Binh Phuoc hospital in 2019
Authors:   Binh Phuoc Hoan My Hospital, Dang Van Dau , Nguyen Duc Thanh , Phung Thanh , Le Hoa Khanh
Published: July 2021

In health administration, the satisfaction of patients is an important factor that need to be achieved by health facilities. This cross-sectional analytical study aims to fulfill two objectives: (1) To describe the satisfaction among inpatients, and (2) To identify some related factors to the satisfaction of inpatients at Hoan My Binh Phuong Hospital. The study took place between April and October 2019 on 300 inpatients and used a questionnaire designed by Hoan My Medical Group based on the Ministry of Health’s satisfaction form. The research results show that the average satisfaction rate of the medical service at Hoan My Binh Phuoc Hospital is 92.27%. The satisfaction of patients on medical examination and treatment is the highest at 96.55%; followed by satisfaction on the time to use the services in the hospital at 94.62%; the satisfaction rate on service attitude of medical staff is 90.96% and on the facilities is the lowest at 86.75%. The study also found that the number of hospitalizations treated in the past 12 months the associated factor to the satisfaction of patients. Key words: satisfaction, inpatient, diagnosis and treatment service.
Evaluate risk factors to unintentional injury and violence of aldolescents in Hanoi 2019
Authors:   Center for Public Health and Ecosystem Research, Nguyen Thanh Luong , Nguyen Thi Khanh Huyen , Nguyen Cong Minh , Pham Quoc Thanh , Nguyen Thi Phuong My , Nguyen Thi Thu Thao , Le Thi Hang , Duong Minh Duc
Published: July 2021

Background: Unintentional injury is the leading cause of death among adolescents. Therefore, research on the risk of unintentional injury among adolescents is imperative in public health because adolescents are the future generations of each country. However, studies on the real situation of unintentional injury and associated factors among adolescents in Vietnam are still limited. Objectives: Describe the situation of risk behaviors towards unintentional injury to adolescent health and associated factors in Hanoi in 2019. Methods: We used a cross-sectional study using multi-stage sampling design. A total of 3,443 subjects who were students from high schools in Hanoi agreed to participate in the study. The data was collected by online self-answered through KoboToolbox software, then aggregated on Microsoft Excel and analyzed by STATA 14.0 software. Results: Fourteen percent of students said that they used to smoke, 51.6% said that they used to drink alcohol. About 6.9% of adolescents said they rarely or never wore a helmet, 30% said they had at least once used the phone and 8.2% admitted that they had ever drank alcohol, beer before driving. Regarding the group of violent behavios, nearly 4.8% of students have been carrying weapons with them in the past 30 days, 6.5% have had at least 1 fight in the past 12 months, 2.4% said that they had been sexually abused at least once and about 11.6% of the students said that they had experienced bullying at school. Smoking (OR = 2.21), drinking alcohol (OR = 2.08), and had psychology problems for 2 weeks (OR = 1.61) had increased the risk of performing risk behaviors that may lead to the unintentional injuries. Conclusions and Implication: The prevalence of adolescents in Hanoi who engage in risk behaviors that can lead to unintentional injury was high. Factors such as smoking, drinking or having psychological problems increased the risk of these behaviors. We recommend that family and school should educate for adolescents to raise the awareness when driving and avoid substance abuse. In addition, family and school also need to promptly detect school violence and provide psychological supports when adolescents experienced psychological problems. Keywords: unintentional injury, smoking, alcohol use, adolescent, Hanoi
Assessment of smoking susceptibility among Hanoi highschool-student and some related factors, 2019
Authors:   Hanoi University of Public Health, Vu Tri Duc , Van Nguyen Hai , Nguyen Ngoc Bao , Tran Thi Ha , Nguyen Viet , Nguyen Thi Thanh Xuan , Pham Thi Hoang Anh , Le Tu
Published: July 2021

Nowadays, the smoking rate among adolescents in Vietnam is still high regardless of many regulations have been implemented. One of the predictors for smoking behaviour in adolescents is smoking susceptibility. This study aimed to describe the rate of students smoking susceptibility and some associated factors. Method: This cross-sectional study was conducted to assess students from 14 randomly selected high schools in five districts in Hanoi. The questionnaire was developed based on “Youth Risk Behavior Surveillance System” (YRBSS) tool. Results: There were 3272 students completed the survey. 4.9% (95% CI: 4.2 – 5.8%) of the students were susceptible to smoking. In the urban areas, this rate was 7.7% and in the suburban areas was 3.4%. While being male (OR=2.79, 95% CI: 2.29 – 3.41), being 16-17 years old (OR=1.25, 95% CI: 1.01 – 1.56), studying in urban areas (OR=1.41, 95% CI: 1.15 – 1.74) and seeing other people smoke, including family members (OR=1.39, 95% CI: 1.14 – 1.70), teachers (OR=1.8, 95% CI: 1.23 – 2.63), friends (OR=2.33, 95% CI: 1.88 – 2.89), and school staffs (OR=1.63, 95% CI: 1.17 – 2.26) smoking was associated to susceptibility to smoking behavior, attending anti-tobacco course (OR=1.31, 95% CI: 1.06 – 1.62) or seeing anti-tobacco messages (OR=1,28, 95% CI: 1,005 – 1,63) reduced the likelihood of smoking susceptibility. Conclusion: Thus, it is necessary to initiate anti-tobacco intervention programs and implement more extreme regulations to reduce susceptibility to smoking rates in adolescents and diminish smoking prevalence in adolescents. Keywords: Susceptibility, smoking, adolescent, high-school, Ha Noi
Current situation and some associated factors with reading books of full-time bachelor students of Hanoi University of Public Health in 2019
Authors:   Hanoi University of Public Health, Nguyen Cong Minh , Nguyen Hoang Nam , Tran Thi Huyen Trang , Tran Thi Thanh , Nguyen Ngoc Son , Vu Thi Hau , To Nguyen Thuy Anh , Do Manh Tien , Tran Thi Tuyet Hanh
Published: July 2021

Objective : Reading is a crucial academic behavior, which directly affects the formation of personality and develops people's thinking. In the higher education environment, reading culture helps students acquire new knowledge quickly and effectively. However, in recent years, young people and students tend to be lazy to read books, afraid of reading academic books while prefer reading comics and novels. At the same time, the dominance of the internet and audio-visual equipment makes reading in schools and universities become less attractive. This study was conducted with two objectives: (1) To describe the current situation of reading culture; and (2) To identify some factors affecting the reading culture of full-time bachelor students in Hanoi University of Public Health in 2019. Thereby, contributing to raise students' awareness about the roles of reading and providing information to help improving the quality and performance of the university’s library. Methods: The study was conducted on 420 full-time bachelor students from the first year to the fourth year, belonging to four majors of the Hanoi University of Public Health in 2019. Main findings: The study results showed that among 420 full-time bachelor students, 41.0% read books on a regular basis and 80.0% liked reading books. With regression bionary logistic analasys, associated factors with reading frequency includes: Going to library weekly (OR=1,87; p=0,004; CI95%: 1,22 – 2,84) and Completed reading the document assigned by teachers (OR=1,61; p=0,043; CI95%: 1,01 – 2,55). In addition, students who were reading addiction were likely to read all the book assigned, which was higher than the students who did not like reading. Conclusions: With full-time Bachelor students at Hanoi University of Public Health, percentages of students with frequent reading behavior were not high in general. However, it could be seen that the reading behavior of students was influenced by the teachers’ activities. Therefore, teachers should enhance checking books and course materials that students have read before classes as well as setting a criteria on the minimum number of academic books students should read while doing their assignments so that students are more aware of the importance of academic reading while studying at university. Keywords: reading books, college students, current situation, associated factor
Hormone use and gender afirmation surgeries among transgender population in Vietnam
Authors: Pham Nguyen Ha , Nguyen Van Luyen , Pham Van Anh , Do Thi Bich Ngoc , Nguyen Thi Loi , Le Hung Viet , Do Thi Van
Published: July 2021

Objective: To describe the current situation of hormone use and surgical interventions of transgender population in some provinces and cities in Vietnam. Research methodology: Cross-sectional descriptive study, combining quantitative and qualitative. Quantitative data was collected by direct interviews using questionnaires with 141 transgender people and qualitative data was collected through 12 in-depth interviews. The study was carried out in Ha Noi, Ho Chi Minh City, Nghe An and Da Nang, from June to October 2019. Results: All 141 study participants have used hormones (100%) and 32 had gender affirmation surgeries (23.4%). More than 73% bought hormones from existing users and use hormones with “mouth to mouth” advice. Among the transgender people who had surgeries, 25% did not have pre-surgery medical checks ups and consultations and 25% had improper check-ups, 50% did not have good care after surgeries and 25% had improper care. Three themes have been identified: 1) Buying "floating" hormones of unknown origin and using them in "mouth to mouth" ways; 2) The painful and risky journey of surgery and 3) A difficult life and uncertain future. Conclusion: Most study participants bought hormones and used them without professional guidance. Insufficient pre-and post-surgery examination, counselling and care. Many bad consequences may arise. Law on Gender Affirmation will help transgender people access safe and quality health services. Keywords: Transgender; Gender affirmation; Hormonal therapy; Transgender surgery; Transsexual law
Satisfaction of caregivers for under 6 years-old inpatients with treatment services and its related factors at Cai Lay district hospital, Tien Giang province in 2020
Authors: Nguyen Phuong Ha , Bui Thi My Anh , Nguyen Hung Vi
Published: July 2021

Objective: Describe the satisfaction of primary caregiver of under 6 years-old inpatients and determine some related factors at Cai Lay district hosptial, Tien Giang province in 2020. Methods: A cross-sectional study was conducted in 2020 with a total of 360 caregivers for under 6 children inpatients. The research measurement utilized a standardized tools developed by the Ministry of Health, Vietnam. Results: The main findings showed that the percentage of general satisfaction among caregivers of under 6 years-old inpatients was 67.6%, the satisfaction with infrastructure and equipment with a lowest rate with 63.2%. The factors related to patient satisfaction include economic situation, marital status, age, education level, health insurance, number of medical check-ups in the past 12 months and length of stay in hospital. Conclusion: In order to further improve the satisfaction of caregivers for under 6 children inpatients with treatment services, the attitude of medical staff with patients should be improving. Moreover, strengthening a process of maintain and upgrade infrastructure and equipment in Pediatric department and hospital. Also, there is a need of improving the quality of medical examination and treatment services covered by health insurance. Keywords: Satisfaction; primary caregiver; inpatient; pediatric patient,…