bluuebunny/crossref_metadata_2025 huggingface dataset:
The effect of intravitreal antiangiogenic diabetic macular edema treatment on the corneal endothelium cell count
Authors: Amirkulieva Regina N. , Khomyakova Elena N. , Loskutov Igor A. , Agammedov Mushviq B.
Published: June 2024

BACKGROUND: Antiangiogenic treatment of diabetic macular edema is a first-line therapy in modern ophthalmology. Novel antiangiogenic drugs are increasingly being developed to improve treatment results and solve certain issues. However, owing to the advent of new drugs, more questions arise about their effect on the patient’s retina and other structures of the eye, such as the cornea.
AIM: The study aimed to investigate the effect of intravitreal administration of the anti-VEGF drug brolucizumab on the corneal endothelium in patients with diabetic macular edema.
METHODS: 106 patients (106 eyes) were included in the prospective study: 31 men and 75 women. The main group consisted of 56 patients (56 eyes) were included in the prospective study: 14 men and 42 women with different stages of diabetic retinopathy with diabetic macular edema, the average age of patients was 62.2±8.4 years. The average number of endothelial cells per 1 mm2 in these patients before the loading dose of brolucizumab was 2378.9±393.3 cl/mm2. The control group included 50 patients (50 eyes) without diabetes who did not receive intravitreal injections or any other surgical interventions on the examined eye for 1 year. All patients underwent endothelial microscopy using the Tomey EM-4000 endothelial microscope (REN 2017/6294), estimated: CD (the number of endothelial cells per 1 mm2); CCT (the central thickness of the cornea, microns); CV (the coefficient of variation, %); 6A (the proportion of hexagonal cells, %). All study participants received intravitreal injections of brolucizumab in a volume of 0.05 ml (5 injections with an interval of 6 weeks).
RESULTS: In the main group before intravitreal injections, the indices of the central corneal thickness and the number of endothelial cells per 1 mm2 were 549.7±30.1 microns and 2378.9±393.3 cells/mm2, respectively. After a course of antiangiogenic diabetic macular edema therapy, the central thickness of the cornea was 548.2±30.6 microns, and the number of endothelial cells per 1 mm2 was 2382.3±424.9 cells/mm2. The indicators CV (coefficient of variability, %) and 6A (proportion of hexagonal cells, %) before the start of intravitreal injections were 36.9±5% and 46.8±6.3%, respectively, after the introduction of the loading dose drugs, the average values were 37.9±4.3% and 45.8±6.3%. Changes in all indicators were not static significant.
CONCLUSION: The use of brolucizumab as therapy in patients with diabetic macular edema did not cause a negative effect on the cornea, there were no statistically significant changes in the central thickness of the cornea, the number of endothelial cells per 1 mm2, the coefficient of variation and the proportion of hexagonal cells.
Transparency of COVID-19 information: a comparison of open data transparency dashboards
Authors: Sano Hironobu , Matheus Ricardo , Vaz José Carlos
Published: June 2024

This paper aims to analyze the transparency features of COVID-19 dashboard created by Brazil, Germany, The Netherlands, and, United Kingdom governments. These dashboards are webpages that present data in different format, such as text, maps, graphs and tables, and can reduce information asymmetry between the government and people. This paper relies on a combination of varied literature to build a Dashboard Transparency Evaluation Framework: Open Government Data, websites transparency assessment, dashboard functionalities and information flowchart, and collaborative stakeholder participation in open government processes. Based on an exploratory approach this paper adopted the structured search and evaluation method to investigate and evaluate the dashboards portals. This paper concludes that data are shown in different formats in all countries and with different functionalities and thus can help people follow the evolution of the disease and also the policy decision. However there is room to improve transparency, such as the integration of dashboards with open data policies and access to information or the interoperability with legacy systems. Future research can advance in the analysis of the users demand, articulation between stakeholders, state technological capacity among others.
Aceitação de tecnologias E-Health
Authors: Fettermann Diego , Calegari Luiz Philipi
Published: June 2024

Despite the potential benefit of using e-health systems to share health information, the relationship between technology and its suppliers with potential users tends to be complex. Thus, it is important to interpret the factors that explain the acceptance of new technologies by potential users. This work aims to synthesize the results of acceptance of e-health technologies. For this purpose, relations and constructs proposed in the UTAUT model of technology acceptance were used. In addition, the effects of moderating variables (gender, age group, presence of illness, users, technological application and year of publication) were tested in the relationships proposed at UTAUT through the procedure called meta-regression. There is significance in the effect of the constructs "Performance Expectancy", "Expectation of Effort" and "Social Influence" in the "Behavioral Intention" construct. It is also possible to observe the significance of the effect of the Behavioral Intention and “Facilitating Conditions” constructs in the “Use Behavior” construct. Among the moderating variables, only the variable “age group” did not result in significant moderation for any relationship. The present study presents estimates of the factors that determine the acceptance of new health technologies and suggests a general orientation for the development of new e-health technologies considering their acceptance by users.
Transformação digital na esfera pública
Authors: Moresi Eduardo Amadeu Dutra , Silva Alves Wanderson Aparecido da , Silva Ana Paula Bernardi da , Hedler Helga Cristina
Published: June 2024

Technology has been a driver for the growth and prominence of many organizations in recent years. Digital transformation is directly associated with both the growth and sustainability of leading organizations around the world. Organizations are challenged to understand and evaluate the dynamics of the digital economy rules and undergo digital transformation to stay relevant in the digital economy. The objective of this study is to conduct a bibliometric survey on digital transformation, identifying the most relevant and emerging correlated topics that are influencing the business value addition of organizations. The methodology used was a literature review employing the Scopus database and the VOSviewer and Gephi tools for analysis and generation of keyword co-occurrence networks, co-citation of references, bibliographic coupling of documents, and identification of emerging issues. To deepen the knowledge about the identified topics a content analysis was performed, among other techniques. It was found that the implementation of digital transformation in the organization depends on the maturity level in electronic governance of the organization and that the use of an IT governance framework helps in a successful implementation.
O fluxo da informação na criação de um microlearning sobre economia
Authors: Lopes Roberto Felipe
Published: June 2024

Introduction: The area of ​​education is important for a Circular Economy, as the transition to circular models requires individuals and organizations that learn to innovate and put into practice what they have learned in the real world. This area, from elementary school to graduate school, plays a vital role in ensuring that students of all ages are equipped with the key skills and knowledge to execute circular thinking in their careers. Objective: Map the information flow stages present in the MOOC production process on Circular Economy. Methodology: This research is characterized as exploratory in terms of its objectives and analyzes the flow of information in the process of creating an informational product with regard to procedures. Results: This research showed that an activity of an interdisciplinary nature, such as Information Management - which evolves over time, mainly due to technological innovations - contributed to mapping the stages of needs, obtaining, treatment, distribution, use, storage and disposal of information from the information flow within the process of developing an information product – in this case, the IEC MOOC. Conclusion: Associated with the concepts of information architecture, information design and information ergonomics, GI helped in the structuring, organization and presentation of educational information, optimizing the transmission of knowledge and user experience.
Estudios sobre la organización y representación de la información en un contexto museológico.
Authors: De Paula Josefa , Cristina Leite da Silva Eva
Published: June 2024

Registrar información hoy en día ha sido uno de los mayores desafíos, ya que la masa de información aumenta con el tiempo. Para utilizar registros de información es necesario que sean recuperables. La necesidad de organizar la información para recuperación ha sido objeto de estudios, que posibilitan diálogos entre campos del saber que tienen como instrumento la información, a saber, la Museología y las C. I. El presente trabajo presenta un levantamiento bibliográfico acerca de los estudios de Organización de la Información  y Representación de la Información en un contexto museológico, con el objetivo de profundizar la comprensión de este tema, tanto la IO como la RI. Para ello,se adoptó como metodología el Análisis de Contenido de Bardin, desarrollado en la búsqueda de un conjunto de Anales que constituyen los mayores indexadores científico sobre el tema de este trabajo.Tratar de un posible diálogo de la Organización y Representación de la Información en los Museos, muestra la preocupación en explorar un tema poco expresivo en las bases de datos de eventos e investigaciones, si se relaciona con otros temas más recurrentes. El diálogo entre OI y RI para el acceso a la información en las instituciones museológicas facilita el acceso a la información tanto para el público que accede a estos lugares como para los profesionales que tienen contacto con la documentación museológica. Y, sin embargo, corrobora el desarrollo de las prácticas en el campo de la Museología, las C. I. y afines, a través de la difusión de la información.
Analysis of knowledge production in Applied Social Sciences in Scientific Initiation
Authors: Pereira Batista Andreza , Belmont de Farias Gabriela
Published: June 2024

Higher education institutions play a vital role in generating scientific knowledge through programs like scientific initiation scholarships. Mapping the publications produced through these programs is a key method for assessing and highlighting the development of knowledge. This study examines the scientific outputs of . This article aims to analyze the scientific output of the Programa Institucional de Bolsas de Iniciação Científica (PIBIC) of the Federal University of Ceará, focusing on the communication mediums employed by researchers (e.g., journal articles, conference proceedings). Employing an exploratory, descriptive, and documentary research design with a mixed-methods case study approach, the research utilizes scientific initiation reports as data, categorized based on publication outcomes. The analysis focuses on projects within Applied Social Sciences (SAS) and is statistically grounded in theoretical frameworks related to the Qualis ratings of publications on the Plataforma Sucupira of the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CNPq). The findings reveal that scientific outputs from these initiation projects primarily take the form of journal academic papers and conference proceedings. Mapping these outputs provides a representative sample of the university's scholarly production, addressing institutional, scientific, and societal needs, and thereby supporting the educational development of undergraduate researchers in scientific initiation, a principal goal of the PIBIC program.
ACEPTACIÓN DE LAS TECNOLOGÍAS DE E-SALUD:UN ESTUDIO DE METAANÁLISIS
Authors: Fettermann Diego , Philipi Calegari Luiz
Published: June 2024

A pesar del potencial beneficio del uso de los sistemas de e-Salud para compartir datos de salud, la relación entre la tecnología y sus proveedores con los potenciales usuarios tiende a ser compleja. Por eso, es importante interpretar los factores que explican la aceptación de nuevas tecnologías por parte de estos usuarios. Este trabajo tiene como objetivo sintetizar los resultados de aceptación de tecnologías de e-Salud disponibles en la literatura. Para ello, se utilizaron las relaciones y los constructos propuestos en el modelo de aceptación de tecnología UTAUT. Además, se probó los efectos de las variables moderadoras (género, grupo etario, presencia de enfermedad, usuario, aplicación tecnológica y año de publicación) en las relaciones propuestas en el modelo UTAUT mediante el procedimiento de metarregresión. Se observa la importancia en el efecto de los constructos “Expectativa de Rendimiento”, “Expectativa de Esfuerzo” e “Influencia Social” sobre el constructo “Intención de Comportamiento”. También es posible observar el sentido del efecto de los constructos “Intención de Comportamiento” y “Condiciones Facilitadoras” sobre el constructo “Comportamiento de Uso”. Entre las variables moderadoras, solo la variable “grupo etario” no resultó en moderación significativa para ninguna relación. Este estudio presenta estimaciones de los factores que determinan la aceptación de nuevas tecnologías para la salud y sugiere una orientación general para el desarrollo de nuevas tecnologías de e-Salud considerando su aceptación por parte de los usuarios.
E-HEALTH TECHNOLOGY ACCEPTANCE: A META-ANALYSIS
Authors: Fettermann Diego , Philipi Calegari Luiz
Published: June 2024

Despite the potential benefits of e-health systems in sharing health information, the relationship between technology providers and potential users is inherently complex. This study aims to elucidate the factors driving the acceptance of new technologies among users by synthesizing results on the adoption of e-health technologies using the constructs and relationships outlined in the Unified Theory of Acceptance and Use of Technology (UTAUT) model. Additionally, the impact of moderating variables—including gender, age group, presence of illness, user types, technological application, and publication year—was examined through meta-regression. Significant effects were observed for "Performance Expectancy," "Effort Expectancy," and "Social Influence" on "Behavioral Intention," as well as the influence of "Behavioral Intention" and "Facilitating Conditions" on "Usage Behavior." Among the tested moderating variables, all except for "age group" demonstrated significant moderation effects in various relationships. This research provides detailed estimates of the factors influencing the acceptance of new health technologies and offers strategic directions for the development of e-health systems, considering user acceptance. It contributes to a deeper understanding of the complex interplay between e-health systems and their users, highlighting the importance of tailored approaches to enhance technology adoption.
Correlaciones de la teoría de la representación y la teoría de la intencionalidad: contribuciones a la encontrabilidad de la información
Authors: Alves Sanchez Fernanda , Ferreira de Castro Fabiano , Fernando Fernando , Borsetti Gregorio Vidotti Silvana Aparecida
Published: June 2024

La teoría de la representación y la teoría de la Intencionalidad son conceptos emergentes de áreas del conocimiento como la psicología, la filosofía y las ciencias cognitivas. En el campo de la C. I., la representación de la información es un concepto ya consolidado; sin embargo, existen pocos trabajos sobre la teoría de la intencionalidad. Ante el paradigma poscustodial es posible afirmar que los sujetos informativos son individuos activos en el escenario socioinformativo, que aplican su intención de producir, organizar representar y buscar información en diferentes tipos de entornos informativos digitales. Esta investigación busca identificar las correlaciones existentes entre las teorías de la representación y de la intencionalidad en el contexto de la C. I.,  para verificar contribuciones a la encontrabilidad de la información, concepto cuyo abordaje incluye perspectivas teórico-prácticas para diseños, implementaciones y evaluaciones de entornos informativos. Es una investigación bibliográfica y exploratoria, con enfoque cualitativo en el análisis de bases de datos como el Portal de Periódicos de Capes, BRAPCI y Google Scholar. Entre los resultados de la investigación, fue posible identificar correlaciones en los conceptos de la teoría de la representación y de la intencionalidad, así como la importancia de los fundamentos de estos conceptos para potenciar la encontrabilidad de la información. Finalmente, se concluye que existe la necesidad de profundizar los estudios sobre la intencionalidad en el área de la C. I., dada la escasez de investigaciones, además de la relevancia que adquiere al posicionar el sujeto informativo dentro del concepto de encontrabilidad de la información.
Human gut microbiota as a potential source to treat obesity
Authors: D Sumitha , D Aboorva , Daniel Joseph C. , S Megala , P Gayathri
Published: June 2024

The human gut microbiome is crucial to human health, illness, and diseases. These bacteria support the host system in a number of ways. Nonetheless, it appears that the species composition and alterations in the gut microbiota contribute to obesity. Screening of potential gut microbiota is inevitable at this point to address multiple health issues in the field of medical microbiology.

Characterizing the gut microbiota of healthy individuals and determining the presence of inclinations to degrade cholesterol, which may aid in the treatment of obesity, were the objectives of the study.

For this investigation 30 isolates were isolated from the faecal samples of the selected healthy individuals. On the basis of the morphological and biochemical features, 17 out of 30 isolates were selected for further studies. Based on colony morphology and biochemical tests 8 isolates were selected for screening of cholesterol degradation and lecithinase enzyme production. The ability of the selected isolates to withstand acidic pH was then examined throughout a variety of pH values. Additionally, their ability to withstand bile salts at various oxbile concentrations was examined. Based on the isolates' results, which demonstrate strong functional properties, 16s rRNA sequencing was used as a molecular methodology to identify them.

The study's findings showed that the majority of the isolates that were chosen were non-motile, urease negative, catalase and oxidase negative. Lecithinase production was also negative in every isolate. Among the selected isolates 8 of them were selected for screening of cholesterol degradation. Two of the eight isolates that were chosen demonstrated the ability to degrade cholesterol, as evidenced by their production of two short chain fatty acids such as butyric and lactic acids. The ability to withstand different pH and bile concentrations were examined. High bile concentrations and low acid pH were conditions that both isolates could withstand and develop in. Based on the isolates' results, which demonstrate strong functional properties, 16s rRNA sequencing was used as a molecular methodology to identify them. It was determined that the isolates were MN294515 and MN535170.

The majority of the cultures found in this investigation were gram positive bacteria. The two isolates of MN294515 and MN535170 can be further studied to determine which probiotic is more effective in treating obesity, a long-standing condition.
The impact of COVID-19 pandemic on seasonal influenza virus
Authors: Pandey Aparna , Pandey Pooja , Das Suman , Agarwal Priti , Pandey A.K. , Gupta Rajiv Mohan
Published: June 2024

: The COVID-19 pandemic and subsequent implementation of non pharmaceutical interventions reduced transmission of Influenza viruses. The WHO has also noticed a drop-in influenza virus cases; however, it hasn't been precisely characterized. The prospect of concurrent influenza and COVID-19 outbreaks is a major concern for public health professionals. Therefore, in this study, we present our limited data on seasonal influenza activity during COVID -19 period (November 2021–October 2022).

A retrospective analysis was conducted in 100 positive and 100 negative COVID-19 cases to look for co-infection with Influenza viruses. Influenza screening was performed with multiplex real-time RT-PCR using standardized techniques for Influenza H1N1/H3N2 with Inf-B on archived respiratory samples.

A total of 8% Influenza cases were found with coinfection in only 05 cases denoting a drop of influenza infection during this period. Influenza A(H1N1) was the most common influenza virus followed by Influenza B (lineage not determined).

The clinical outcomes of co-infections could not be anticipated and may worsen if novel COVID-19 variants continue to appear. The use of community mitigation measures for the COVID-19 pandemic, are likely to be effective in reducing the incidence of seasonal influenza.
Phenotypic detection of ESBL and Amp C beta lactamase among clinical isolates of Enterobacteriaceae
Authors: Thakar Vrushali , Gandavalli Brundha , Devhare Deepa , Modak Meera , Sawant Shailaja , Kumar Mahadevan , Bhatawadekar Sunita
Published: June 2024

Emergence of ESBL & amp C β-Lactamase enzymes among clinical isolates of poses a significant public health concern. Antimicrobial agents like 3 generation cephalosporins, clavulanic acid, imipenem etc. can induce amp C enzyme production. Sometimes the automated antimicrobial susceptibility testing systems fails to detect Amp C phenotype due to presence of multiple resistance mechanisms in gram negative bacilli. To overcome such difficulty, the study was undertaken to detect the presence ESBL and Amp C enzymes among clinical isolates of by phenotypic methods.

strains isolated from various clinical samples were included in the study. Strains resistant to two or three groups of antibiotics (MDR) were further tested for the presence of ESBL enzyme by combination disk method. Amp C enzymes were detected by cefoxitin- cloxacillin disc method.

A total1059 strains were isolated from various clinical samples. Out of these, 170 MDR strains were further processed. ESBL enzymes were detected in 104 (61%) strains and Amp C in 35 (20.5%) strains. 26(15.2%) strains were co-producers.

Detection of ESBL and Amp C enzymes will help clinician in choosing the right antimicrobial treatment for the patient. Routine reporting of presence of Amp C & ESBL enzymes by phenotypic methods can be easily implemented by clinical microbiology laboratory. Cefoxitin-cloxacillin disk test is simple & rapid method for detection of Amp C β- lactamase enzyme.
Occurrence and types of carbapenamase enzymes amongst enterobacterales and Pseudomonas spp. using automated phenotypic method
Authors: Dave Rajal Pranav , Chavan Sumit Sonaba , Angadi Kalpana Mohan
Published: June 2024

The continuous rise of Carbapenem Resistant Organisms, considered as one of demanding public health issue. Carbapenemase producing organisms (CPO) can be detected by various molecular and phenotypic methods. Although molecular method shows higher accuracy, but is limited by relatively complex procedure and expensive regents. Thus, phenotypic methods considered as routine CPO detection method. Automated system Phoenix M50 (Becton & Dickinson) CARBA panels, provides the advantage of simultaneous identification and characterization of carbapenemase enzymes.

A retrospective study was conducted for various clinical samples received at a tertiary care center in Western Maharashtra during a period of one year. The bacterial identification and antimicrobial susceptibility testing performed by automated system Phoenix M50 (Becton & Dickinson) CARBA panels. Isolates which flagged as carbapenemase producers were confirmed using modified carbapenemase inactivation method (mCIM) as a part of protocol.

Among all isolates of enterobacterial and . 32% were carbapenemase producers. identified as predominant strain. Class B MBL was 46.4 % of isolates, consisting of appeared at 40% followed by at 35.5%. Class D beta-lactamase the second, the majority found in K.pneumoniae at 27.23%, followed by at 30 %. For Class A, 56 % followed by 26 % (n=67) isolates found in K.pneumoniae. The most isolates were Urine 16.6% followed by Pus 7.29 %, Respiratory 4% and blood 4%.

A high occurrence of carbapenemase producers observed in the study is concerning. Moreover, most of them belonged to Class B MBLs, which demonstrated the need antibiotic stewardship and hospital infection control strategies to prevent their further spread.
Use of various substrate/ media for germ tube test (GTT) detection in Candida albicans and Candida dubliniensis from a tertiary care hospital
Authors: Kotgire Santosh , Hatkar Sunil
Published: June 2024

In recent years, non-judicious use of broad spectrum antibiotics, corticosteroids, antineoplastic agents, immune suppressive drugs, widespread increased use of bone marrow and organ transplant, and unreasonable use of indwelling catheters have led to an increased incidence invasive candidiasis (IC). The germ tube test (GTT) is a well established, inexpensive, rapid and easy to dispense test used to identify . So the present study was conducted to assess the reliableness of different media for GTT production in and .

A total of 102 and 09 strains were obtained from various clinical samples received at Department of Microbiology from a teaching institute and hospital located at west- central part of Maharashtra for a period of nine months. Medium that were employed for production of germ tube in and C.dubliniensis in the present study were trypticase soy broth, YEPD (Yeast Extract Peptone Dextrose) broth, Muller-Hinton agar/broth and peptone water which were assessed and compared with pooled human sera routinely used for detection of germ tube.

For both the isolates human pooled serum showed 96.39% positivity followed by YEPD (yeast extract peptone dextrose) broth with 92.79% positivity, Trypticase soy broth showed 80.18% positivity, whereas Muller Hinton broth produced 67.56% positivity and least positivity was seen with Peptone water where only 45.04% of germ tube induction was observed.

So our study clearly highlights that YEPD broth is better serum free media for germ tube production. Moreover, this medium is available commercially, is more stable, reliable, effective, is non biohazardous, convenient and cost effective alternative.
In-house Carba NP - II test to identify and differentiate carbapenemase-producing Gram-negative bacteria among various clinical isolates in comparison with immunochromatography assay
Authors: Tak Heena , Amber Tabassum , Kapaganty Vamsi Chakradhar
Published: June 2024

Resistance to Carbapenems has increased drastically resulting in ineffective treatment, prolonged hospital-stay, increased morbidity and mortality. A cost-effective in-house test that can differentiate carbapenemase enzymes belonging to different Amblers Class can emerge as an important tool in middle and low-income countries for guiding the clinicians in selecting the most appropriate antibacterial therapy. Cost effective commercial ICT kits are also available now for the same use.

1. To adapt an in-house test that can identify and differentiate Ambler class carbapenemase enzymes among the clinical isolates of multi-drug resistant Gram-negative bacteria (GNB); 2. To evaluate the commercially available immunochromatography (ICT) lateral flow assay of carbapenemase detection in comparison to in-house Carba NP – II test

A prospective study conducted in the Department of Microbiology of NRI Institute of Medical Sciences, Visakhapatnam. All GNB isolates irrespective of source, age and gender, were considered in the study. A total of 565 GNB isolates were obtained, which were subsequently tested for Meropenem resistance by routine antimicrobial susceptibility test (AST), out of which 195 isolates were further tested for carbapenemase resistance by in-house Carba NP - II test and ICT (Bio-State Inc).

Out of 565 isolates, 195 were Meropenem resistant, 120 belonged to Class B and 75 to Class D by in-house modified Carba NP-II test. In ICT, 117 belonged to Class B and 73 to Class D and 5 isolates showed both the enzymes of Class B and D. No class A enzyme was detected in our study by either method.

Carba NP - II Test is a reliable and cost-effective test with similar results in comparison to commercially available ICT.
Microbiological profile and antimicrobial susceptibility patterns of blood stream infections in febrile neutropenic patients with hematological malignancies in a tertiary care hospital, Kolkata
Authors: Ganguly Bhattacharjee Swagata , Mandal Sayan , Mullick Soma Sil , Bhunia Somnath , Kundu Suman , Banik Ankita , Mallick Tanvi , Behera Kishor Kumar
Published: June 2024

Blood stream infection (BSI) in febrile neutropenic (FN) patients with hematological malignancy is a common manifestation with high mortality rate. To reduce mortality knowledge of pathogens causing BSI and their antimicrobial susceptibility patterns are required for timely initiation of appropriate antimicrobial therapy. This study was aimed to characterize the pathogenic spectrum and antimicrobial resistance patterns of BSI in these patients.

In this cross-sectional study patients admitted in the Hematology department over a period of one year with laboratory confirmed positive blood cultures were enrolled. Information regarding demographic profiles and microbiological profiles were recorded. Standard procedures were applied to identify the isolates and their resistance patterns in positive blood culture. Data was collected and analyzed on MS-Excel sheet with various charts and tables.

During the study period of one year 198 episodes of BSI recorded in 147 FN patients. Majority of isolates were Gram-negative bacilli (GNB: n=107, 54.04%). Among GNB (n=34, 31.77%) was most frequently isolated and in Gram-positive cocci (GPC) majority isolated was (n=37, 62.71%). (n=12, 37.5%) was the commonest fungal pathogen isolated. Susceptibility to penicillin, clindamycin and quinolones were least among GPC. Among GNB higher resistance patterns were observed against ceftazidime, cefepime, cefoperazone-sulbactam, piperacillin-tazobactam and meropenem. All isolates were resistant to fluconazole.

This study revealed a significant increase in proportion of Gram-negative non-fermenting bacteria (GNNFB). These findings highlight the necessity for regular revision of institutional antimicrobial policy which will reduce mortality as well as development of resistant pathogens.
A machine learning approach to forecast wind speed based on geographical location in Bangladesh
Authors: Shipra Elmeeh Hasan , Rahaman Md Sujaur , Ara Tasnim , Ullah Saeed Mahmud
Published: June 2024

This paper examines a learning approach to forecasting wind speed based on geographical location in Bangladesh. Most people use wind energy, a rapidly expanding renewable energy source, to produce electricity, replacing traditional fossil fuel-based electricity generation. The variable nature of wind speed necessitates an accurate estimate for planning wind power generation and grid integration. Machine learning models, based on various methods, commonly make wind speed predictions. This study implements machine learning algorithms, namely Random Forest Regression, XGBoost Regression, Multi-Layer Perceptron Regression, Ridge Regression, and Lasso Regression, to determine wind speed prediction accuracy. Firstly, we divide the dataset on wind records of Bangladesh into seven categories, each encompassing different geographical locations in Bangladesh, to account for the change in wind characteristics based on location, and then apply the algorithms to each category. The performance metrics Mean Absolute Error, Mean Squared Error, and Root Mean Square Error are utilized to draw comparisons. The findings showed that the performance of XGBoost makes it the most reliable tool for predicting wind speed in Bangladesh. The near proximity to large water bodies causes considerable variation in accuracy, i.e., it showed higher accuracy compared to the other three algorithms after applying the ensemble learning approach, which is more effective and accurate. This research will help in identifying optimal power plant locations and efficient linking methods to Bangladesh's power grid, ensuring smooth electricity access and efficient utilization of the country's energy resources.
Investigating the influence of green human resource management practices on employee behavior and organizational commitment in Ghana’s tourism sector
Authors: Obeng Hayford Asare , Arhinful Richard , Mensah Leviticus , Osei Dennis Affum
Published: June 2024

This study investigates the influence of green human resource management practices on the environmentally conscious actions of employees in Ghana’s tourism sector. We collected data from 481 employees in selected hotels using a quantitative methodology through snowball sampling. We employed structural equation modelling in AMOS (Analysis of Moment Structures) version 23 for data analysis. The results revealed a statistically significant positive impact of green human resource management practices on in-role green behavior, extra-role green behavior, and green innovative work behavior. Additionally, a significant and positive correlation was identified between green human resource management practices and employees' organizational commitment. Furthermore, organizational commitment exhibited a substantial impact on innovative green work behavior, and extra-role green behavior, and in-role green behavior. Notably, the relationship between green human resource management practices and employees' green behavior facets was found to be mediated by organizational commitment. This study provides valuable insights for promoting environmentally friendly behaviors in the tourism industry through the implementation of green human resource management practices and fostering organizational commitment.
Evaluation of antibiotic resistance changes in Acinetobacter baumannii in the era of COVID-19 in Northern Iran
Authors: Rahimzadeh Golnar , Valadan Reza , Rezai Shaghayegh , Khosravi Mohammad , Larijani Laleh Vahedi , Sheidaei Somayeh , Hevelaee Ebrahim Nemati , Movahedi Faezeh Sadat , Rezai Raha , Rezai Mohammad Sadegh
Published: June 2024

Background and Objectives: During the coronavirus pandemic, the overuse of antibiotics to reduce coinfections and mor- tality may be contributing to the rise of antimicrobial resistance. In this study, we aim to investigate the antibiotic resistance changes of Acinetobacter baumannii post-COVID-19 pandemic in Northern Iran.
Materials and Methods: The current study is a cross-sectional study. Between 2022 and 2023, 2190 clinical samples were collected from patients with healthcare-associated infections (HAIs) at four hospitals in Sari, which served as corona centers after the COVID-19 pandemic. Antimicrobial sensitivity was determined using standard broth macro-dilution, and resistance genes were detected using multiplex PCR.
Results: Based on the results co-amoxiclav had a resistance rate of 100%, while piperacillin/tazobactam showed the least resistance rate of 29.82%. In terms of GM MIC values, colistin was the most potent against multi-drug resistant isolates. The frequency of bla OXA-51 , ampC, aphA6, and bla NDM genes were 100%, 99.12%, 90.35%, and 69.30% respectively.
Conclusion: Our study revealed high multi-drug resistance rates. Piperacillin/tazobactam recommended for treating multi- drug resistant Acinetobacter baumannii infections in Northern Iran.
Does Household Access to Financial Services Help Reduce Poverty in Indonesia?
Authors: Yuanita Ika , Sumiarti Elni , Yenida
Published: June 2024

This research aims todetermine propensity of household access to financial services and to examine their impact on helping reduce poverty in Indonesia, Nov-2018 until Feb-2019 by the National Socioeconomic Survey (SUSENAS), March 2019, around 315,672 households. To determine the propensity of household access to financial services, we use a probit model integrated with propensity score matching. With a quasi-experimental design, data were analyzed using the average treatment effect on treated (ATT) by household access to financial services (treatment) within 77,602 households with access (treated) and 238,070 households without access (control) to financial services. Estimation of propensity score was used to reduce selection bias of ATT on the outcome variables. The empirical findings show that household poverty status was reduced which would have occurred if they had access to financial services. Accessing financial services as transitory income has a negative impact, thus we conclude it was an unfavorable income. For poor, it is not yet significant enough but has a positive impact on increasing their expenditure per capita a month, averagely. Thus, the decrease or increase in their incomes didn’t increase or decrease their expenditure in the short-run, but in the long-run, it occurred.
Steroid Abuse Induced Benign Intracranial Hypertension in an Infant
Authors:   Ankura Hospital for women and children, Lb nagar, Hyderabad, Chaitanya Dr Krishna
Published: June 2024

Introduction Idiopathic Intracranial Hypertension is a well known phenomenon in both pediatric population and also adults. Steroid induced Intracranial Hypertension is also well documented in adults but sparsely reported in children and no such literature reported in Infants from India. We would like to present our case of steroid induced intracranial hypertension in a 6 months old male child who was on prednisone drops for past 3 months misused by parents as prescribed by some quack as relief medication for common cold. Our intention is to highlight the level of abuse of steroids over the counter practice and to show the level of detrimental side effects it causes with evidence inorder to report from Indian literature. Case Report A 6 months old male child was brought by parents with complaints of poor feeding, excessive cry and irritability. On examination child (fig 1) had bulging anterior fontanelle, BP was 120/80 mmHg, > 99th centile for the age. Child is obese and weight was 10 kg, Z> 2SD on WHO chart. Child was suspected to be having cushingoid features. On further probing mother gave a history of usage of drops for common cold as suggested by a quack continuously for past 3 months which was found to be Prednisolone drops
Impact of Salinity on Growth and Physiological Responses of Striped Catfish Pangasionodon hypophthalmus Fingerling
Authors: Lingam R. Somu Sunder , Rani A.M. Babita , Rao K. Pothu Srinivas , Paswan Vinod Kumar , Haridas Harsha , Maniraj Natarajan Dhilip , Babu P.P. Suresh
Published: June 2024

Background: A 90-day experiment was conducted to study the impact of salinity on growth and physiological response of Pangasionodon hypophthalmus fingerling at the Brackish water fish farm of Central Institute of Fisheries Education (CIFE), Kakinada Centre, Kakinada, East Godavari District, Andhra Pradesh, India. Method: The study used different salinities condition such as 0 (control), 5 (T1), 10 (T2) and 15 (T3) ppt. Fingerlings (8.47±0.46 g) were gradually acclimatized to different salinities in 1000 l fibre reinforced plastic (FRP) tanks, in triplicates and fed with a commercial feed (crude protein 30%). Result: Growth indicators such as specific growth rate (SGR), feed conversion ratio (FCR), feed efficiency ratio (FRR) and protein efficiency ratio (PER) revealed that growth and survival were negatively affected above 10 ppt salinity. Significantly higher amylase and protease activities were observed up to 10 ppt group. In contrast, significantly higher cortisol (97.71±1.94 ng/ml) and glucose (113.32±2.66 mg/dl) levels in the blood were recorded in 15 ppt group. Overall, the study proved that P. hypophthalmus can be cultured in low saline water (up to 10 ppt) without affecting its growth and physiological homeostasis.
Directive Speech Acts Represented as Teacher Feedback at Indonesian Higher Education Level
Authors: Wirawan Sandy , Chojimah Nurul , Sugiharyanti Eni
Published: June 2024

This study scrutinizes the common types of directive speech act performed by the teacher in the form of written feedback along with its function classification. Descriptive qualitative was used as the research design. For data collection, observation and documentation were used to obtain utterances performed by the speaker. In this regard, one English lecturer at one of universities in Indonesia was chosen teaching one class under the subject of Advanced Reading. Then, thematic analysis was used to analyze and categorize the data set. There were 81 number of data found from this study as directive speech act in the teacher feedback. This study revealed that direct acts were dominant with 50 data while the indirect acts consisted of 31 data. Furthermore, out of six (6) types of directive speech acts, the findings demonstrated that the function of requestives and questions were the most frequent acts performed by the teacher in the feedback. The result of this study suggested that the further research may take account into different criteria of giving feedback, such as the other types of speech acts, the teacher gender, and the subject of the class.
Developing “Reverb English” Textbooks for Kindergarten Students: Is It Effective?
Authors: Khittahira Fikra Raushani , Tyas Peptia Asrining
Published: June 2024

English is one of the foreign languages taught in Indonesia. It has separated curriculum with other subject which are taught in primary, secondary, and high schools by using English textbooks. However, English textbooks are limited to be developed in Kindergarten area. Therefore, this research is conducted and aimed to develop adequate English textbooks based on Kindergarten syllabus which are annual and semester programs by the school. The researcher took the group A and B learners of Kindergarten students at TK Negeri Pembina 1 Malang year 2021/2022. The researcher involved 70 students as the participants. Research and Development (RD) was conducted in this research with the ADDIE model. The instruments of the research were observation, expert validation checklist, interviews, and field notes. The data analysis was obtained from the expert validation checklist also the transcription of the result from the interview with both teachers and students. Findings indicate that “Reverb English” textbooks are feasible and effective during the English teaching-learning process in the classroom for kindergarten students. It can help them to learn faster by visualizing the pictures and words in the book.
Various Strategy in Teaching English Through Literature in Senior High School
Authors: Ulul Azmi Muhammad Bunayya , Maram Mohammad Aufal , Rohmana Wahyu Indah Mala
Published: June 2024

Learning English through literature is one of the various ways to improve our English since it includes many aspects, speaking and listening that are used in daily interaction, and reading skills that cannot be separated from literacy. Various way of teaching method and strategies has been developed in the past few years. Based on the previous explanation, the researchers want to find out the kinds of literature (drama, short stories, novels, song) being taught in the class, and what method is used by the teacher. the school teaching program has already used some kinds of literature in teaching and learning activities. Since there are some branches in literature, the teacher mentioned that the one used are drama, song, and narrative text (poems, short stories, novels). The aim of using this strategy is to strengthen the relationship between two different aspects of educational pioneers so both of them could support and embrace their differences.
The Influence of Tiktok Videos in Increasing Students’ Pronunciation Ability
Authors: Safila Risa
Published: June 2024

This study intended to show the effect of TikTok videos on students’ pronunciation skills . A quasi-experimental study design was used in this study. Students from MAN 2 Probolinggo participated in this study, 20 students consist as an experimental class and consist of 20 students as a control class. The results of this study showed a significant difference between students using TikTok videos as media learning and those using traditional strategies. Post-test results revealed that there was a significant effect of post-treatment on experimental class. Independent test results show that TikTok videos have a significant impact on students' pronunciation skills. However, the mean pretest scores of the experimental class are higher than  the control class. It can be concluded that TikTok videos have a positive effect on students' pronunciation ability and are accepted as an effective learning medium to improve students' pronunciation ability.
Utilizing Canva Platform to Improve Students’ Achievement in English Learning and Teaching
Authors: Maria Bernadin , Februati Noenoek , Yuliatin Umi
Published: June 2024

The issue that this research focuses was the students’ low achievement in learning English. This followed the condition where the students showed their unpreparedness in attending the English learning and teaching program.  To address this problem, the effort to improve the students’ achievement was made by utilizing Canva platform to redesign the present English for Specific Purposes material. This research, therefore, was conducted with the aim of determining whether the students improved their achievement when they used the English learning and teaching material designed with Canva platform. To prove the existence of such improvement, the data was collected from the same group of research subjects consisting of 76 students of Polytechnic of Energy and Mineral through the pre-test and post-test. Both data was, then, compared and the result of the comparison was t = 4.22 which equaled to p-value= 0.000. Since the significance level α = 0.05, it could be said that Null Hypothesis / H0, there was no improvement of the students’ achievement when they used Canva-based designed material, was rejected because p-value α. It meant that the Alternative Hypothesis / H1, there was an improvement of the students’ achievement when they used Canva-based designed material, was accepted
THE INTERSECTION OF ISLAM AND ADAT IN POLITICS: The Pakpak Muslim Community
Authors: Harahap Mardian Idris , Utomo Wahyu Wiji
Published: June 2024

Islam and Tradition in the Sulang Silima Institution have significant social, cultural, and legal impacts, demonstrating substantial political influence. The involvement of Sulang Silima in the election of political leaders illustrates how tradition and Islam unite in political decisions. This research employs a descriptive qualitative method to explore the dominance of Sulang Silima in shaping social and political policies. This method was chosen to understand complex phenomena such as identity politics within the Pakpak community. Data collection techniques include in-depth interviews, participatory observation, and document studies. The collected data are analysed using thematic analysis to identify and categorise key themes, providing a comprehensive understanding of Sulang Silima's role in local politics. This research aims to delve into Sulang Silima's dominance in social and political policymaking, reflecting identity politics in the Pakpak community. The intersection of Islam and tradition within Sulang Silima highlights the roles of these two elements in political intersections. The presence of identity politics has the potential to cause national disintegration. The intersection of Islam and tradition in Sulang Silima is an integral part of the political culture of the Pakpak community, which needs to be analysed to understand the implications of Islam, tradition, and their intersection.