bluuebunny/crossref_metadata_2025 huggingface dataset:
Teaching and Assessing Soft Skills for Health and Education Professionals: A Scoping Review
Authors: Daly Svetlana , Phillips Katrina J. , McCann Clare M.
Published: July 2022

Soft skills are a collection of abilities instrumental to one being a successful professional. Soft skills are knowing why, what, when, and where to perform specific technical, hard skills. Traditionally, universities and other professional training providers have focused on teaching hard skills, relying on graduates to learn necessary soft skills on the job or through personal experiences. With more professional training requiring tertiary education and less work experience, a skills gap has developed between labour markets and professional training providers. A scoping review was conducted to answer two research questions: How are soft skills conceptualised and taught to health and education professionals? How are soft skills assessed for health and education professionals? The PAGER framework was utilised to present and synthesise the scoping review results. Eight themes emerged from the patterning analysis and data synthesis: Lack of definitions of soft skills; What soft skills are taught; Methods of teaching soft skills; Curriculum: Embedded vs. stand-alone courses; Use of digital tools; Assessment of soft skills; Variation of assessment tools; Limited regard for cultural competency, diversity, equality, and inclusion. These themes are discussed in relation to advances, gaps, evidence for practice, and research recommendations.
Impact of International Trade on Economic Growth in Nigeria
Authors: MAKANJUOLA David A. , EKPERIWARE Moses C. , OYETADE John A , ADEWUSI Adeyinka , Tenny Lester Z.
Published: July 2022

Using data from the World Development Indicator (WDI) and the Central Bank of Nigeria (CBN) Statistical Bulletin, this article analyzed the impact of exports, imports, the currency rate, and inflation on Nigeria’s economic development between 1981 and 2020. The research employed Autoregressive Distributed Lag (ARDL) bound testing methodology. The variables utilized in the study were evaluated for stationarity using the Augmented Dickey-Fuller and Philip Perron test, and the bound testing process was applied to the equations. The lag of variables test can be performed to determine the relationship between the variables. The outcome demonstrated that variables are stationary at first difference. Economy growth, exports and imports, exchange rate, and Inflation all exhibit long-term cointegration, as determined by a cointegration test. Export positively impacted on growth while inflation and exchange rate were found to be negatively affecting growth in Nigeria. The article indicates that there is a beneficial association between international commerce and economic growth and supports the policy of encouraging exports and expanding Nigeria’s presence on global markets.
Nso, Mbum and Iyamho Creative Imagination and Social Concerns: The Study of Proverbs
Authors: Dzekem Ngeh Ernestilia
Published: July 2022

This study investigates the relevance of oral performance in addressing social concerns within the context of the three oral communities under study. It contends that the oral literature of the Nso and Mbum people of the North West region of Cameroon and Iyamho people of Edo state, Nigeria lodge cherished African values that are still significant to the people’s conception of development in this evolving society. Every community strives to reinforce positive values in order to enhance development. The paper considers the collection and documentation of proverbs that are on the lips of Nso, Mbum and Iyamho people relevant because this cultural heritage that habours their valuable mores, lores and customs are threatened by globalization. Many have thought that oral literature is outdated and that given its mode of transmission which is by word of mouth, it cannot address serious contemporary social issues. Through the participant observation method and interviews with members of the communities under study, the findings tentatively reveal that orature which generally consists of material that is several generations old and is transmitted orally contains local knowledge systems that can be useful in the discussion in addressing social concerns to enhance sustainable development within the various communities under reference. Considering the crucial position of context in oral literature, new historicism, interpretative cultural translation and pragmatic functionalism theories guided the analysis, and revealed, that since all successful development efforts begin with the right decision which is anchored on good human qualities and resources, the indigenous knowledge system expressed in Nso, Mbum and Iyamho proverbs can be exploited and applied alongside some innovative methods to foster development. The study therefore assumes that since sustainable development anchors on the quality of the mind, we need to conceive our projects locally and think globally.
A NOVEL METHOD DEVELOPMENT AND VALIDATION FOR THE QUANTIFICATION OF NEFOPAM HYDROCHLORIDE IN PARENTERAL DOSAGE FORM BY RP-HPLC METHOD
Authors: NEELIMA CH. , HEMASRI M. , SUSMITHA P. , SRILAKSHMI S.
Published: July 2022

Objective: Using RP-HPLC, a simple, accurate, and exact method for estimating the Nefopam Hydrochloride parenteral dose form was devised.

Methods: The isocratic mode of the RP-HPLC method used an Inertsil C8 column as the stationary phase and a mobile phase of potassium dihydrogen phosphate with pH 3.0: Acetonitrile (70:30) at a flow rate of 1 ml/min. With UV detection at 220 nm, a flow rate of 1 ml/min was established.

Results: The developed RP-HPLC technique revealed acceptable linearity (R2 = 0.9998) and good assay results in the concentration range of 0.004–0.08 mg/ml (103.3 percent). Further forced degradation investigations using 0.1N Hydrochloric acid (acid degradation), 0.1NNaOH (base degradation), and 3 percent H2O2 (Hydrogen peroxide) were carried out using RP-HPLC, and percent degradation values were determined. In peroxide degradation conditions, the medication was shown to be unstable.

Conclusion: In compliance with ICH requirements, the developed procedures were validated.
DESIGN, BINDING AFFINITY STUDIES AND IN SILICO ADMET PREDICTIONS OF NOVEL ISOXAZOLES AS POTENTIAL ANTI-BACTERIAL
Authors: SAI G. CHAITANYA , JAYS JUDY , MADRIWALA BURHANUDDIN
Published: July 2022

Objective: The objective of the study is to design novel isoxazole derivatives, predicting their interactions with the selected target proteins and determining the ADMET properties of potent molecules using recent computational methods.

Methods: With the intent to discover potent novel antibacterial, we have designed a set of compounds containing the isoxazole nucleus by using software tools like Discovery studios, PyRx, PyMOL, SWISSPDB. ADMET studies were carried out by using SWISS ADMET and pkCSM. Molecular docking studies were carried out on the target proteins of both gram-positive and gram negative bacteria in order to assesses binding affinity for the proteins.

Results: Designed scaffold was designed by Benzene Derivatives Tethered with 5(4-chloro-3-nitro phenyl-1-yl) isoxazole. All the derivatives were docked against the three proteins, namely DNA Ligase (PDB ID: 3PN1), Topoisomerase (PDB ID: 3TTZ), Sterol demethylase (PDB ID: 5FSA), The compound JJC3F has shown best binding score against DNA ligase, sterol demethylase protein. Further, compound JJC3A has shown a better binding affinity towards topoisomerase than the standard drugs.

Conclusion: Molecular Docking study indicates that isoxazole derivatives may be effective inhibitors for the different microbial proteins. Additionally, in silico ADMET studies predicts drug-like features. Hence, these compounds may be considered as leads and further investigation of their analogues may help in development of novel drugs for the treatment of microbial diseases.
Del puñal a la espada: una lectura simbólica en la literatura de Jorge Luis Borges
Authors: Esquivel Alva Víctor Manuel
Published: July 2022

El presente artículo aborda un análisis de los motivos literarios representados por las armas blancas en los libros El Aleph, Ficciones y El informe de Brodie de Jorge Luis Borges. Demuestra que aparecen de manera recurrente en la obra de Borges, desde sus relatos de atmósfera culta, hasta sus cuentos de cuchilleros, asociados con una persistente fascinación por la muerte en todas sus manifestaciones, a menudo violentas. Dada esta naturaleza violenta, estos referentes implican todo un paradigma de objetos, situaciones y motivos particulares y pertinazmente repetidos en el discurso, incluso como temas principales del mismo, rebasando con ello su categoría de meros objetos presentes en la vida misma para constituirse en signos de segundo grado. Al ser simbólicamente antagonistas del monstruo pero, al mismo tiempo, también el propio monstruo, poseen un valor ambiguo, positivo o negativo que se transmite a su poseedor, dependiendo de su tipología y el contexto en que se insertan. Armas distintas caracterizan personajes específicos, desde el héroe, el santo y el semidiós, hasta el monstruo encarnado en el poder militar y la traición, pero siempre orientadas en la dirección de la venganza, el martirio y el sacrificio como formas dinámicas organizadoras de paradigmas enteros de signos. La comprensión de dichos signos, bajo esta perspectiva, permite advertir una serie de significados profundos en la relectura de estas obras.
La personificación como recurso literario: fundamentos, forma y funciones
Authors: Galicia Lechuga David
Published: July 2022

El presente trabajo propone un estudio de la figura retórica de la personificación a partir de la comprensión de las construcciones del pensamiento humano que la motivan, la forma lingüística en que se expresa y las funciones que realiza en los textos literarios. Se plantea en una primera instancia que la personificación, entendida como la ficción retórica que presenta a una entidad no humana como si fuera humana, parte de una forma de organización jerárquica del mundo conocida como la escala del ser, la cual ha sido configurada a partir de la noción de ser humano, persona y yo. En segunda instancia, se trata de mostrar la expresión de la personificación a partir de la gramática española, tanto en el nivel oracional como en el textual. Por último, se propone que esta figura presenta en el discurso literario cuatro funciones: ornato, concreción de ideas o entidades, creación de personajes y la formación de un mundo ficticio. Se proponen así las bases para un entendimiento más completo de la personificación como recurso literario.
A Study on Ordering Policy with Time-Varying Demand and Holding Cost for Deteriorating Items with Shortages
Authors: Sharma Dr. Mamta , A. Dr Raveendra Babu
Published: July 2022

Abstract: The present paper focuses on time varying demand and holding cost, taking the same into consideration a finite horizon inventory problem for a deteriorating item has been developed for study. Deterioration rate is considered as a linearly time-dependent. The demand rate varies with the time until the shortage occurs, but during the tenure of shortages it becomes static i.e. constant. Shortages are considered to be a partially backlogged in this study. In the study it is also considered that the backlogging rate is inversely proportionate to the length of the waiting time for next recovery. The main objective of the study is to minimize to the total cost of inventory with optimal order quantities of the products in the system. The graphs in the study show the convexity of the cost function. Finally, numerical results are discussed and presented in the section 5 of the study to analyze the degree of sensitivity of the optimal policies with respect to variations in the economic parameters of the model.
Comparative Analysis of PEB Structure with Varying Bay Spacing
Authors: Isal Anushri A. , Gore N. G.
Published: July 2022

Abstract: Pre-designed buildings are nothing more than steel buildings in which excess steel is avoided by narrowing sections according to the requirements of the moment of bending. The PEB concept is widely used in many industrialized countries. It consists of a complete steel frame building system with components pre-designed to combine into a variety of combinations to meet the unique requirements of specific end goals. If we go for conventional steel structures, the time frame will be longer and the cost will be higher, and both together, ie time and cost, make it uneconomical. This study analyzes the structure of PEB using STAAD-PRO software when the distance between bays changes.
The development of a singing play program model: Based on the kindergarten and elementary school community
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Ryu Ji Won , Kweon Mee Ryange , Chio Eun Ji
Published: July 2022

Objectives This study tries to develop a new teaching model of Singing Play in kindergartens and elementary schools based on the community.
Methods This Community-based Singing Play Program was developed based on the ADDIE model. The ADDIE model is a stage of analysis, design, development, implementation, and evaluation. This Singing Play Program model applied to 13 kindergarten and elementary school students in Busan, and a final Singing Play Program model was developed.
Results First, it was confirmed that a community-based Singing Play kindergarten and elementary School linked program could achieve its meaningful goal. Second, a mixed-age community consisting of young and elementary school students is a strong organization that increases feelings of leadership and belonging as a member of the community, which adds meaning and value to communities. Third, the Community Singing Play Program combines traditional and modern background songs with play, thus playing a role in connecting traditional and modern culture for participants. Fourth, not only did the songs used for singing serve as a useful medium for forming communities, but also played the role of ‘play facilitator’ that encouraged the community to engage in the play. Fifth, the activities of singing programs spread to families, aided in the resolving of conflicts between families and distrust and misunderstandings about each other, leading to the restoration of family functions.
Conclusions The Development of Community-based Singing Play Program Model for Connected Education of Kindergarten and Elementary School that it have meaning and value as a program that implements children's and play-oriented curriculum, and the subjects have more leadership and sense of belonging than conflict caused by leadership tattoos or competition during play. In addition, this program played a bridging role in continuing traditional and modern games in this era when play was disappearing.
A Theoretical Study and Therapeutic Suggestion on Psychological Development of Children of Single Mothers: Focusing on Psychodynamic Theories and Parent-Child Interaction Therapy
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Ko Eunae , Kim Hyejeong
Published: July 2022

Objectives The purpose of this study is to examine the psychological development of children of single mothers through psychodynamic theory and to provide therapeutic suggestions.
Methods For this purpose, first, the psychosocial experiences of single mothers were analyzed. Second, the psychological development of children of single mothers was analyzed based on Freud's psychoanalytic theory, Object Relations theory, and Attachment theory. Third, PCIT (Parent-Child Interaction Therapy) was proposed as an alternative intervention to promote the healthy psychological development of children of single mothers.
Results Single mothers have physical, psychological, and social vulnerabilities for raising their children alone in the absence of a partner. From the perspective of psychodynamic theory, the psychosocial situation of single mothers acts as a limiting point for their children's psychological development. Therefore, it is necessary to understand the uniqueness of psychological development of children of single mothers, and psychosocial interventions supplementing for their vulnerabilities are required.
Conclusions Finally, the implications were introduced, and follow-up studies were suggested based on these findings.
The Effects of Coping Flexibility and Proactive Coping on Academic Burnout of College Students: Focusing on Hierarchical Regression Analysis
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Hyun Seungju , Lee Hyunyup , Choi Yoonyoung , Kang Sungrok
Published: July 2022

Objectives This study verified whether college students' coping flexibility and proactive coping predict academic burnout, and additional hierarchical regression analysis was conducted to examine whether coping flexibility and proactive coping predicted academic burnout even when other variables(state anxiety and hypervigilance) known to be related to academic burnout were controlled.
Methods From June 1 to June 6, 2021, 232 college students were recruited from the online communities of five universities, and participants accessed the announced link and conducted an online survey once. The measured scales Coping Flexibility Questionnaire (COFLEX), Proactive Coping Inventory (PCI), State-Trait Anxiety Inventory-Y (STAI-Y), Brief Hypervigilance (BHS), and Korean Academic Burnout Scale. The collected data were analyzed using SPSS 27.0.
Results First, academic burnout showed a significant correlation with control variables state anxiety and hypervigilance, and independent variables coping flexibility and proactive coping. Second, both coping flexibility and proactive coping were significant predictors for academic burnout, and the higher the coping flexibility and proactive coping, the lower the level of academic burnout. Third, coping flexibility and proactive coping significantly predicted academic burnout even after controlling the effects of state anxiety and hypervigilance.
Conclusions These results suggest that interventions that promote coping flexibility and proactive coping in college students can help alleviate the level of academic burnout.
The Effect of Satisfaction with Real-Time Non-face-to-face Education for Nursery Teachers in Childcare Support Center on Educational Effects through Teacher Effectiveness
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Hong Chan Young , Yoon Kyung Soon
Published: July 2022

Objectives The purpose of this study is to examine the influence on education effect by satisfaction level of untact real-time education for childcare teacher-executed by the Support Center for Childcare- with mediacy of teacher’s efficacy and to provide basic data required in managing education program by the Support Center for Childcare
Methods The objects of this study were 204 childcare teachers working at daycare centers in Gyeonggi-do. The survey for satisfaction level of real-time untact education, education effects, teacher’s efficacy was performed from 11 March to 24 March in 2022. Excluding some outlying data, 202 samples was analyzed for this study, and data analyzing tool was SPSS WIN 22.0 program for frequency analysis, reliability analysis, descriptive statistics, difference analysis, correlation analysis, and mediating effect analysis.
Results First, satisfaction level of real-time untact education, education effect and teacher’s efficacy shows high position. Second, among several variables of childcare teacher, number of real-time untact education increases their efficacy for education. Third, between satisfaction of real-time untact education, education effect, and teacher’s efficacy, statical correlation was verified. Fourth, relation between real-time untact education satisfaction and education effect, teacher’s efficacy functions as a mediating parameter. So, plan or alternative for increasing teacher’s efficacy is required.
Conclusions Through this study, we were able to confirm the high satisfaction and educational effects of real-time untact education at the Support Center Childcarere and the mediating effects of teacher efficacy. This can be used as a basic data for the efficient operation of childcare teachers' education at the Support Center Childcarere, and there is an empirical implication in the need to improve the teacher's sense of efficacy.
A Study on the the Expression Items of ≪Reading Joseoneo≫ Textbooks for Students of Joseoneo as a Foreign Language in North Korea: Publications from Kim Hyong Jik University of Education
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Oh Hyeanah
Published: July 2022

Objectives The purpose of this study is to analyze the expression items in the textbook of ≪Reading Joseoneo≫ for foreigners at Kim Hyung Jik University of Education in North Korea.
Methods In Chapter 2, 2.1 of the second chapter, we looked at the list of expression items for the appearance of textbooks, and in 2.2, we tried to analyze the expression items presented in the textbook of ≪Reading Joseoneo≫ by dividing them into ‘language unit dimension, form dimension, and meaning dimension’.
Results As a result, it was confirmed that much more expression items were presented in ≪Reading Joseoneo 3≫ (2016) than in ≪Reading Joseoneo 3≫ (2013). In 2.2, the analysis was conducted by dividing the expression items presented in the textbook of ≪Reading Joseoneo≫ into 1) language unit dimension, 2) form dimension, and 3) meaning dimension.
Conclusions Through the above analysis, we were able to confirm the actual condition of the expression items presented in the high-level textbooks of Kim Hyung Jik University of Education, ≪Reading Joseoneo 3≫ (2013) and ≪Reading Joseoneo 3≫(2016). However, it is necessary to discuss in detail how expression items in North Korean language education for foreigners are actually taught and learned by international students.
The pre-school teacher's childcare practice experience and the director's thoughts on childcare practice in the COVID-19 situation
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Lee Kyungha , Han Namjoo
Published: July 2022

Objectives In this study, the childcare practice experience of childcare trainees operated in the situation of COVID-19 was confirmed, and the ideas of the daycare center manager toward non-face-to-face childcare practice was analyzed to examine ways to improve childcare practice through the parallel between non-face-to-face and face-to-face practice.
Methods A childcare practice diary of 30 third-year students from the Department of Early Childhood Education at a 4-year university in Gyeongsangbuk-do, a reflective self-evaluation of childcare trainees, a survey on childcare practice patterns, and a survey on childcare practice experiences was conducted. In addition, written interviews were conducted on 20 directors of national and public daycare centers in Gyeonggi-do and the contents were analyzed.
Results The childcare practice experience of childcare trainees in the COVID-19 situation was analyzed by understanding the practice daycare center, daily routine guidance, writing childcare practice-related documents, and teacher feedback. It was analyzed that for effective childcare practice, childcare trainees are requesting support to enhance understanding of the individuality of infants and toddlers and to familiarize themselves with different childcare practices by each institution in advance and for support for quick adaptation. The directors of the daycare center generally had negative thoughts about non-face-to-face childcare practices. However, it was analyzed that the production of educational contents to help the understanding of childcare practices according to age was perceived positively.
Conclusions Considering the analysis that non-face-to-face practice is possible, a plan to improve childcare practice found in the COVID-19 situation was suggested in terms of fulfilling the role as a childcare trainee and supporting the effective operation of childcare practice. In fulfilling the role as a childcare trainee, it is necessary to provide opportunities and contents to enhance the understanding of the individuality of infants and toddlers, and to operate childcare practice so that daily life, play, and activities including daily life and activities can be provided. In terms of support for effective childcare practice operation, it is necessary to provide practical orientation, sufficient feedback from supervisors, and education and content related to document preparation related to childcare practice. Therefore, if contents that can supplement face-to-face practice are produced as contents, and non-face-to-face practice and face-to-face practice are carried out concurrently, it is expected to be a more effective childcare practice.
The relationship between Curriculum Noticing and Mathematics Knowledge for Teaching in plan and implementation of Math Class
Authors:   Korean Association For Learner-Centered Curriculum And Instruction, Kang Hyun-Young
Published: July 2022

Objectives In this study, for the math teacher professional development, the relationship between curriculum noticing and the mathematical knowledge for teaching was investigated, and by looking at the lesson plan and implementation through the curriculum noticing.
Methods For the purpose, We examine curriculum noticing and mathematical knowledge for teaching. A case study method was adopted to collect and analyze data on a specific case, and one high school math teacher was selected as the study target.
Results First, the curriculum noticing affects enacting lesson by influencing the process of developing and selecting tasks to be used in class in the lesson plan. It was confirmed that HCK, one of mathematical knowledge for teaching, affects the process of curriculum noticing. It is influenced by how it is used in the curriculum noting. Third, the process from teacher's lesson plan to implementation can be seen as a process of decentralization to PCK by using SMK in curriculum noticing.
Conclusions This study, the curriculum noticing in the lesson plann and implementation and the role of the knowledge of the math teacher and follow-up tasks were suggested for the professional development of the math teacher.
Evaluation of the relationship between inflammation and bone turnover by sclerostin and Dickkopf-1 (DKK-1) levels in patients with SIRS
Authors: ALTINIŞIK Hatice Betül , ALTINIŞIK Uğur , AŞIK Mehmet
Published: July 2022

Introduction: In intensive care units (ICU), patients remain bedridden for a long time. In addition, severe infections are frequently seen in ICUs. Both prolonged immobilization and serious infections are associated with bone tissue loss. The Wnt pathway has recently been focused on evaluating bone tissue loss. The Wnt pathway participates in both infections and the formation of bone tissue. Wnt pathway inhibitors sclerostin and Dickkopf-1 (DKK-1) inhibit bone formation and increase osteoclastic activity. In this study, we aimed to examine bone turnover by the Wnt inhibitors sclerostin and DKK-1 and their possible associations with inflammation in SIRS patients.Methods: We included 30 patients diagnosed with systemic inflammatory response syndrome (SIRS) in the study group and 16 in the control group. Serum sclerostin, DKK-1, white blood cell (WBC), and C-Reactive Protein (CRP) levels on the day of SIRS diagnosis (basal), the 7th, 14th, and 21stdays were evaluated in the study group, and the results were compared with the control group.Results: When the control group was compared with the basal SIRS, there was a significant elevation in both sclerostin (p=0.003) and DKK-1 (p=0.001). Statistical analysis showed significant decreases in sclerostin levels between basal and the 7th, 14th, and 21st days (p=0.033, p=0.003, p=0.002, respectively). Similarly, significant decreases in DKK-1 levels between basal and the 7th and 21st days (p=0.015, p=0.001, respectively) and an insignificant decrease on the 14th day (p=0.191) was observed. Sclerostin was positively and significantly correlated with WBC and CRP in basal and 7th-day measurements and WBC in 7th and 14th days. DKK-1 is positively and significantly correlated with WBC in basal and 7th-daymeasurements, while DKK-1 negatively correlates with CRP in basal-7th-day measurements.Conclusion: In this study, it was shown for the first time that the Wnt antagonists sclerostin and DKK-1 values are high in SIRS patients in ICU. Both biomarker levels decreased in parallel with the treatment. However, it could not be associated with disease severity and inflammatory marker levels. We believe that monitoring the change of Wnt antagonists will be useful in demonstrating bone turnover in patients with SIRS.Keywords: Dickkopf-1, Intensive care unit, Sclerostin, Systemic inflammatory response syndrome, Wnt signaling pathway, Bone turnover
Festivais de cinema e curadoria: uma abordagem contemporânea
Authors: Ikeda Marcelo Gil
Published: July 2022

O presente artigo busca apresentar um olhar panorâmico sobre a contribuição dos estudos contemporâneos dos festivais de cinema, utilizando abordagens interdisciplinares para considerá-los como um campo difuso, composto por agentes e dinâmicas heterogêneos. Em seguida, buscaremos mostrar como essas transformações abrem espaço para o curador como agente estratégico, que atua e interfere na conformação desse circuito. Por fim, vamos examinar essas questões por um panorama pelo circuito dos festivais de cinema no País, em especial sua consolidação a partir dos anos 1990, em termos de sua multiplicidade e heterogeneidade.
The Incompetent Antagonism of Wit: A Study of Hamlet and Catch-22
Authors: Shifana P. A.
Published: July 2022

Unique among other rhetorical devices, wit can appear complex and banal simultaneously. The clever language can express thought equal to the weight of lengthy discourse in a few words, often with amusing effect. However, despite the complexity of the device, wit only offers a momentary chuckle or clarification of events, easily forgotten in a larger context. This dichotomy of wit operates the plot and theme in many literary texts. Intelligent protagonists employ the device to remedy their problems, believing that the complexity of the response ensures its effectiveness. However, because wit consists of only words, the device falls short of enacting change that action or direct discourse could more appropriately handle. This paper examines the role of wit in Hamlet and Catch-22 to determine how characters rely on wit to affront their problems but succeed only in amplifying them.
A stakeholder opinion-led study to identify canine priority diseases for surveillance and control in the UK
Authors: Cuartero Carmen Tamayo , Radford Alan D. , Szilassy Eszter , Newton Richard , Sánchez-Vizcaíno Fernando
Published: July 2022

Many pathogens cause disease in dogs, however, meaningful surveillance
in small companion animals is often only possible on the most impactful
diseases. We describe the first stakeholder opinion-led approach to
identify which canine infectious diseases should be prioritized for
inclusion in surveillance and control strategies in the UK. Participants
were identified through a stakeholder analysis. A multicriteria decision
analysis was undertaken to establish and weight epidemiological criteria
for evaluating diseases, and a Delphi technique was employed to achieve
a consensus among participants on the top-priority canine diseases.
Leptospirosis and parvovirus were identified as the top two endemic
diseases of concern, whilst leishmaniasis and babesiosis were the top
two exotic diseases. Respiratory and gastrointestinal diseases were
identified as the top two syndromes of concern. Findings from this study
are being used to inform the development of a future UK-wide epidemic
response strategy. This methodology could provide a blueprint for other
countries.
Rapid discrimination of Pseudomonas aeruginosa ST175 isolates involved in a nosocomial outbreak using MALDI-TOF Mass Spectrometry and FTIR Spectroscopy coupled with Machine Learning
Authors: Rodríguez-Sánchez Belén , Candela Ana , Arroyo Manuel J. , Sánchez-Cueto María , Marín Mercedes , Cercenado Emilia , Méndez Gema , Muñoz Patricia , Mancera Luis , Rodriguez-Temporal David
Published: July 2022

Objectives: Evaluation of Matrix-Assisted Laser Desorption
Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) and Fourier
Transform Infrared-Spectroscopy (FTIR-S) as diagnostic alternatives to
DNA-based methods for the detection of Pseudomonas aeruginosa
sequence type (ST) 175 isolates involved in a hospital outbreak.
Methods: Twenty-seven P. aeruginosa isolates from a 2014
outbreak in the Hematology department of our hospital were previously
characterized by PFGE and WGS. Besides, 8 P. aeruginosa isolates
were analyzed as unrelated controls. MALDI-TOF MS spectra were acquired
by applying the colony on the MALDI target plate followed by 1 µl of
formic acid 100% and 1 µl of HCCA matrix. For the analysis with FTIR-S,
colonies were resuspended in 70% ethanol and sterile water according to
the manufacturer instructions. Spectra from both methodologies were
analyzed using Clover Biosoft® software, that allowed data modelling
using different algorithms and validation of the classifying models.
Results: Three outbreak-specific biomarkers were found at 5169,
6915 and 7236 m/z in MALDI-TOF MS spectra. Classification models
based on these three biomarkers showed the same discrimination power
displayed by PFGE. Besides, K-Nearest Neighbor algorithm allowed the
discrimination of the same clusters provided by whole-genome sequencing
and the validation of this model achieved 97.0% correct classification.
On the other hand, FTIR-S showed a discrimination power similar to PFGE
and reached correct discrimination of the different STs analyzed.
Conclusions: The combination of both technologies evaluated,
paired with Machine Learning tools, may represent a powerful tool for
real-time monitoring of high-risk clones and isolates involved in
nosocomial outbreaks.
Sedación intravenosa en domicilio tras fracaso a la sedación subcutánea
Authors: Illan Varella Andrea , Crespo Andrea , Illan Selene , Panadero Sonia
Published: July 2022

La vía subcutánea representa la vía de elección en el manejo de los síntomas del paciente oncológico paliativo. De especial importancia en domicilio, resulta fundamental para plantear sedación en situación de agonía. Por otro lado, es habitual que el paciente oncológico dispongo de catéteres centrales de acceso periférico debido a los múltiples ciclos de medicación citostática que reciben a lo largo de su vida.
Por ello, y ante la situación de fracaso a la sedación por vía subcutánea en situación de últimos días, podría plantearse como alternativa la sedación endovenosa a través de estos dispositivos, en domicilio. Esta hipótesis de trabajo se pone de manifiesta en base a nuestra experiencia de sedación intravenosa a través de reservorio venoso central (RVC) en paciente con diagnóstico de adenocarcinoma de páncreas estadio Iv en situación de agonía. La paciente falleció con buen control de síntomas y sedación completa en domicilio.
Estimation of liquid density using artificial neural network in gamma-ray scattering measurement
Authors: Tam Hoang , Sang Truong , Anh Nguyen , Trung Tran , Quang Vu , Dat Nguyen , Nhat Lam , Chuong Huynh
Published: July 2022

The feasibility of an artificial neural network for the estimation of the
liquid density, in gamma scattering measurement, has been investigated in
this paper. The liquid density was estimated using a well-trained artificial
neural network model with only two input parameters: the scattering angle
and the ratio of the area under a single scattering peak for a liquid
relative to that for water. It is worth noting that the whole training data
was generated by carrying out the Monte Carlo simulation using Monte Carlo
N-Particle code. The results indicated that the artificial neural network
model exhibits a good correlation between the estimated and reference
densities, at all the investigated scattering angles, with a relative error
below 5.5 %. Next, the trained model is used to predict the liquid density
with the input data of being the experimatal data, which yield the relative
deviation between the predicted density and the reference one, mostly less
than 5 % (only three cases with deviation in the range from 5-8.1 %). The
obtained results demonstrated that the model developed in this work gives
more accurate results within the defined conditions.
The decline of educational hypergamy in the former Yugoslav republics
Authors: Gligorijevic Vera , Bakic Damjan
Published: July 2022

This paper examines marital market preferences and opportunities, given the
gender asymmetry of education and the limited supply of equally educated
partners (especially in the higher education segment), and explores
selection patterns resulting from new composite changes for at-risk
populations entering into a marriage. Specifically, we are researching mixed
marriages by education and changes in the patterns of that selection in the
former Yugoslav republics. The assessment of the impact of changes in
educational characteristics by gender on patterns of marital pairing and the
reduction of the level of educational hypergamy was performed by analysing
the movement of F-index and H-index values from 1970 to 2020 and their
correlation coefficient. The results showed that educational hypergamy is
declining in all countries and that the decline in hypergamy is positively
associated with the predominance of women among highly educated individuals.
Religious xenophobia in the everyday consciousness of Russian progressive youth: Risk assessment
Authors: Shapovalova Inna , Lebedev Sergey , Blagojevic Mirko
Published: July 2022

This article is devoted to the sociological analysis of the attitudes of
religious xenophobia among the most socially and culturally developed part
of modern Russian youth, represented by students. The research discourse is
formed at the intersection of the problems of ?risk society?, revitalisation
of religion, and xenophobia. The main purpose of the study is to obtain a
reflexive assessment of the religious characteristics of Russian students in
terms of xenophobic reactions, discrimination, and violations of citizens?
rights on religious grounds. The method of data collection was a mass survey
of Russian students from one of the regions of the Russian Federation. It
was revealed that at least 20% of students find some extremist practices
around them. The internet is the leading platform for xenophobic and
extremist antisocial practices. In the environment that young people
observe, religious xenophobia has a much larger scope than it would seem,
and the ?isthmus? that brings it into a position of extremism is much
narrower than it appears at first glance. The lack of understanding of the
continuity between the phenomena of xenophobia and extremism constricts the
area of management of the situation and creates the possibility of critical
risks of conflicts with destructive consequences.
Hepatic Markers Profile in Cytolysis and Cholestasis during Antiretroviral Treatment at the Charles de Gaulle University Hospital
Authors: Soudre Fabienne Marie
Published: July 2022

Introduction: Mother-to-child transmission of HIV is a public health problem for sub-Saharan African countries. Systematic antiretroviral treatment at diagnosis is an important step in the evolution of HIV/AIDS management. However, this treatment can be the cause of hepatic adverse effects. The aim of this study was to evaluate the profile of hepatic cytolysis and cholestasis markers in children living with HIV under ARV treatment at Charles de Gaulle Pediatric University Hospital (CHUP-CDG). Materials and Methods: This was a descriptive cross-sectional study from February to June 2018 in which markers of cytolysis (AST, ALT, and LDH) and cholestasis (ALP and γGT) were studied in children living with HIV 1 undergoing ARV treatment at CHUP-CDG. Results: The markers of hepatic cytolysis, ALT, AST and LDH, were elevated in 11.63%, 13.95% and 26.74% of children on ARV treatment, respectively; as were those of hepatic cholestasis (ALP=77.91% and γGT=12.79%). Cytolysis and hepatic cholestasis were more marked in children with CD4 counts below 400/mL. In addition, when the viral load was less than 500 copies/mL and when the duration of treatment was more than 12 months, the proportions of these liver biological disorders were higher in children on ARV treatment. Conclusion: The disturbances observed on cytolysis and cholestasis markers were slightly elevated, but without serious consequences because they were mostly at low toxicity levels.
fumaças no antropoceno
Authors: Guedes Brigante Gustavo , Lutaif Lopes Thamirez
Published: July 2022

O artigo teve por objetivo discorrer sobre os incêndios Pantanal a partir de duas modalidades do uso do fogo: a primeira performada por sociedades caçadoras-coletoras (tomando como pano de fundo, sobretudo, a etnia indígena yanomami) e a segunda performada por uma lógica de expansão capitalista e colonialista. Apreciamos as queimadas yanomami a partir do que Anna Tsing classifica como “perturbações lentas” e os incêndios à serviço do capital a partir do que a autora classifica como “perturbações rápidas”. Com isso, investigamos as condições e os potenciais dos modos de “habitar”, conforme a noção desenvolvida por Tim Ingold, tendo em vista essas duas modalidades. Argumentamos que há uma linha de continuidade que perpassa tanto as fumaças dos incêndios à serviço do capital quanto as “fumaças” que constituem a pandemia do novo coronavírus de acordo com a cosmologia yanomami sobre a queda do céu ou fim do mundo. Ambas as “fumaças” também são caracterizadas como eventos de “perturbação” rápida. Por fim, foi considerada a possibilidade de um devir-onça e de um devir-indígena a partir da noção de “devir-animal” tratada por Gilles Deleuze e Félix Guattari como maneiras de “segurar” o céu. A metodologia utilizada foi a revisão bibliográfica e documental.

Palavras-chave: 1. Covid-19. 2. Fogo. 3. Yanomami. 4. Devir-animal.
Lideranças políticas no Brasil
Authors: Viveiros de Freitas Eduardo Luiz
Published: July 2022

O NEAMP (Núcleo de Estudos em Arte, Mídia e Política do Programa de Estudos Pós-graduados em Ciências Sociais da PUC-SP), inscrito no Diretório dos Grupos de Pesquisa no Brasil do CNPq (Conselho Nacional de Desenvolvimento Científico e Tecnológico), produziu nos últimos 25 anos. diversos projetos de pesquisas, orientações de iniciação científica, mestrados e doutorados, seminários, encontros, workshops, grupos de trabalho em eventos científicos nacionais e internacionais que resultaram em produções acadêmicas nos mais variados suportes de divulgação e publicação (artigos, livros, relatórios científicos, pareceres, vídeos, anais de eventos acadêmicos e científicos etc.).
imanência da criação artística
Authors: Duarte Elandia Ferreira , Araujo Adele Cristina Braga , Sobral Karine Martins , Dos Santos José Deribaldo Gomes
Published: July 2022

O artigo objetiva apresentar elementos acerca do método estético de análise. Com base sobretudo em Lukács, o texto opta por realizar um estudo teórico-bibliográfico que se fundamenta no materialismo histórico-dialético. Com essa metodologia, aborda-se a imanência da criação artística como proposta de análises de obras de arte, cujo exame estético não deve se dar sobre a subjetividade do criador, tampouco sobre a recepção, senão sobre a imanente relação que se forma entre a obra, o receptor e o criador. Esse debate possibilita que o artigo aponte o seguinte: o confronto entre a produção artística e a práxis cotidiana abre possibilidades para que o crítico possa adequadamente analisar se a obra reflete realmente os autênticos dramas humanos
PERANCANGAN IT BALANCED SCORECARD DI PERGURUAN TINGGI
Authors: Ilahiyah Mar’a Elthaf , Palupi Dian
Published: July 2022

The implementation of the MEA competition in the field of higher education is undeniably very closely related to the industrial revolution 4.0 where all teaching and learning process systems no longer use traditional systems but require the practice of using advanced IT technology (Information Technology). The study took the object of the UNISLA private university in Lamongan, emphasizing a qualitative case study approach to see how the implementation of IT components became a Balanced scorecard strategy at UNISLA. There are several strategic goals in implementing the IT balanced scorecard at UNISLA, among others (financial perspective: cost efficiency and profit oriented, customer perspective: increasing the satisfaction of UNISLA users including students, lecturers, and education staff, internal business perspective: developing the use of IT as a the main foundation in UNISLA business processes, learning and growth perspectives: evaluation of IT improvement in UNISLA and improvement of UNISLA users' skills.) From the explanation above we can conclude that why the application of IT in the Balanced Scorecard is so important to be applied as a support in the industrial revolution 4.0.
Pendidikan Diniyah: Dinamika TPQ-TQA dan MDT (Awu) dan Sejenisnya Dalam Pengembangan Pendidikan Islam di Indonesia
Authors: Husna Ridhatul , Zulmuqim Zulmuqim , Zalnur Muhammad
Published: July 2022

This study aims to explore the Al-Quran Education Park (TPQ) is an institution that is engaged in religious activities, as well as the Al-Quran Education Park (TPQ) which should be a very appropriate institution to develop Islamic symbols in terms of deepening read the Qur'an properly and correctly and the madrasa diniyah from a historical perspective. This research is using a library approach. Madrasah Diniyah provide awareness for the Islamic Community about the existence of Religious Education. In its development, it has led to the renewal of Islamic education. In the next phase of Madrasah the diniyah have still received recognition from the government as part of the national education system in Indonesia. It also has a level of education such as basic education which is called madrasah diniyah ula or Awaliyah.
Digital comic learning media based on character values on students’ critical thinking in solving mathematical problems in terms of learning styles
Authors: Darmayanti Rani , Sugianto Rahmad , Baiduri Baiduri , Choirudin Choirudin , Wawan Wawan
Published: July 2022

To prepare students to compete in 21st-century skills, the Ministry of Education and Culture of the Republic of Indonesia integrates character education into school subjects. However, as a medium, comics do not contain the level of character values, exploration, and critical thinking skills in problem-solving on geometry material. Therefore, the aim of this study is to produce digital media based on character values on mathematical critical thinking skills in solving problems related to learning styles for eighth-grade students. This development research employed the 4-D method (Define, Design, Develop, and Disseminate). The study indicates that the digital comic learning media is valid with a total average score of 3.60 based on the material expert’s validation and 3.50 based on the media expert’s validation. The eight-grade students' responses were positive (92%) based on the trials. The learning outcomes in terms of kinesthetic, auditory, and visual learning styles used in this study can all meet all indicators of mathematical problem-solving.