bluuebunny/crossref_metadata_2025 huggingface dataset:
Association between parental autoimmune disease and childhood atopic dermatitis varied by sex: a nationwide case–control study
Authors: Hung Yu-Hsuan , Liu Hsin-Yu , Chang Renin , Huang Jing-Yang , Wu Cheng-Dong , Yen Man-Syuan , Hung Yao-Min , Wei James Cheng-Chung , Wang Paul Yung-Pou
Published: November 2022

Atopic dermatitis(AD) is a common inflammatory skin disorder induced by dysfunction of immune suppression, which resembles the mechanism of autoimmune diseases. To explore the association between autoimmune diseases and AD in their children, we linked the birth data from National Birth Registry with National Health Insurance Research Database. Demographic characteristics from 1174,941 parent-child linkages were obtained. There were 312,329 children diagnosed with AD before 5 years old, and they would be compared with the other 862,612 children without AD in the control group. Conditional logistic regression was utilized to calculate adjusted odds ratio (aOR) and 95% confidence interval (CI). After adjusting infant’s characteristics, perinatal factors, and other parental diseases, the odds ratio of parental rheumatoid arthritis(RA) was 2.269 (95% CI 1.333–3.861) and parental psoriasis was1.610 (95% CI, 1.094–2.369). Parental allergic diseases such as AD (aOR 2.071, 95% CI 1.952–2.198) and asthma (aOR 1.494, 95% CI 1.400-1.594) were also significant predictors for childhood AD. The subgroup analysis showed significant difference between children’s sex. Parental RA (aOR 3.070, 95% CI, 1.532–6.154) was crucial for boys, while parental psoriasis (aOR 1.945, 95% CI, 1.129–3.350)was a risk factor for girls. In conclusion, parental autoimmune diseases were found to be related to AD in their children before 5 years old. Additionally, there were different risk factors for AD between children’s sex.
Combining phylogenomic and morphological data reveals new patterns of diversity in the national tree of Brasil, Paubrasilia echinata
Authors: Rees Mathew , Neaves Linda E. , Lewis Gwilym Peter , de Lima Haroldo Calvacante , Gagnon Edeline
Published: November 2022

Paubrasilia echinata (Lam.) Gagnon, H. C. Lima & G. P. Lewis (“Pau Brasil”) is the national tree of Brazil and an endangered species endemic to the Brazilian Atlantic Forest. The extensive range of distribution, spanning over 2000 km distance, is matched by extensive plasticity in leaf morphology. Three morphotypes are commonly identified based on the size of the leaflets but it is unclear if they represent distinct taxa or a single polymorphic species. This study aims to clarify the taxonomic position of the three morphotypes to inform conservation decisions. A comprehensive morphometric study based on herbarium specimens from the entire distribution range of the species was coupled with genetic analyses of population structure using genotype-by-sequencing data. We found that the three morphotypes do not match separately evolving lineages. Rather, P. echinata is composed of five genetic lineages that are geographically structured, although we did find evidence of genetic admixture in two individuals. Leaflet size varied by over 35-fold and although morphological clustering generally matched the genetic patterns, there were some overlaps, highlighting the cryptic diversity within this group. Finally, our genetic and morphological results provide some evidence that cultivated trees from different states in Brazil seem to be most closely related to a genetic lineage from northern Brazil, which suggests that more care is needed to protect and preserve the overall genomic diversity of this highly endangered and iconic species.
WITHDRAWN: Receiver mount design, tag depth, and wind speed affect detection probability of acoustic telemetry tags in a Missouri River tributary
Authors: Carlson Tanner L. , LaBrie Lindsey A. P. , Wesner Jeff S. , Chipps Steven R. , Coulter Alison A. , Schall Benjamin J.
Published: November 2022

BackgroundOne of the most important considerations for acoustic telemetry study designs is detection probability between the transmitter and the receiver. Variation in river conditions and flow regimes among river systems can lead to differences in detection probability between systems. In this study we evaluate the detection probabilities of two acoustic tag models at various distances from stationary receivers, for two different mount designs, at two different tag depths, and across varying wind speed. InnovaSea V16-6H (hereafter V16) and V13-1L (hereafter V13) tags were deployed in the James River, SD at a deep depth of 0.36 m above the benthic surface or at shallow depths of 2.29 m (V16 tag) or 1.98 m (V13 tag) above the benthic surface downstream of stationary receivers at distances of 100, 200, or 300 m. Two receiver mount designs that included a fixed position on bridge pilings in a PVC pipe or in a midriver frame, were used to detect acoustic signals. Tags were deployed for 72 hrs at each location, and hourly detections were summarized and compared to the expected number. We assessed downstream distance, receiver mount design, tag depth, and wind effects on tag detection using Bayesian logistic regression.ResultsTag detection was high (>70%) at 100 m, >50% at 200 m, and lowest but variable at 300 m for the V16 tags. Tag detection was nearly 100% at 100 m, >50% at 200 m, and <10% at 100 m for the V13 tags. Detection probability was improved for the pipe mount when V16 tags were deployed at deep locations. There was no effect of tag depth or receiver design for the V13 tags. Wind had a strong, negative effect on the shallow V16 tag but no effect on the V13 tag.ConclusionsOverall, mounting the receiver in a PVC pipe was more secure, and detection probability was greater for the V16 tag than the V13 tags. This study demonstrates the detectability of acoustic telemetry tags to downstream distances of at least 200 m in a Missouri River tributary.
Adult Patient Satisfaction With Nursing Care Services and Associated Factors Among Admitted Patients at Saint Paul’s Hospital Millennium Medical College, Addis Ababa, Ethiopia, 2022: a Cross-sectional Study
Authors: Bogale Bantalem Amanu , Ahmed Sindew Mahmud , Gebrekidan Aynie Birhane , Bogale Getachew Amanu
Published: November 2022

Background: Around the world, providing holistic nursing care and ensuring patient satisfaction have become crucial health-care performance indicators. Despite a lot of efforts to improve patient satisfaction with nursing care, the approach in the developing world, including Ethiopia, is still insufficient.
Objective: The aim of this study was to assess adult patients’ satisfaction with nursing care services and identify the factors affecting satisfaction at Saint Paul’s hospital millennium medical college, 2022.
Methods: Cross-sectional study was conducted at Saint Paul’s hospital millennium medical college. A simple random sampling technique was used to select 422 study participants. The actual sample was distributed using proportional allocation for each selected adult inpatient departments. Participants were interviewed using a modified structured Amharic version of ‘Newcastle Satisfaction with Nursing Scale’ tool from June 20/2022 to July 30/2022. Data analysis was made by SPSS version 26. Bivariate and multivariable logistic regression analysis was used to identify factors associated with adult patient satisfaction. Statistical association was declared using 95% CI and a p-value of < 0.05.
Results: The overall level of patient satisfaction with nursing care was 54.3%. Respondents who had no formal education (AOR=8.482; 95% CI=1.678-42.87), being male (AOR=2.487; 95% CI=1.038-5.959) (P-value=0.041), free service consumers (AOR=6.650; 95% CI: 2.677-16.517), health insurance user (AOR=7.309; 95% CI=3.122-17.110) (P-value=0.000), was significantly associated with satisfaction with nursing care. In addition patients’ who had admission history (AOR=0.261; 95% CI=0.122-0.560), governmental workers (AOR=0.090; 95% CI=0.026-0.310) (P-value=0.000) and patients admitted in medical ward (AOR=0.160; 95% CI=0.039-0.649) (P-value=0.010) were associated with patient dissatisfaction with the nursing care services.
Conclusion and recommendations: The finding showed that patient satisfaction with nursing care was rated low. Admission history, higher education level, paid cash for service, private and governmental workers were significant predisposing factors to dissatisfaction with nursing care. On the other hand, patients who had no formal education, free service consumers, and being male were significant predictors of satisfaction with the nursing care services. Therefore, it is recommended to include all communities with health insurance schemes and the hospital administration to better give emphasis to patient needs and expectations.
Transpiring as an institution of hope through an assessment of students’ cognizance, understanding, and acceptance of the VMGO of the College, Institute, and Degree Program
Authors: Lobo Joseph
Published: November 2022

The existence of every college and university is based upon its VMGO. The goals and ambitions of schools are solely guided by their mission and vision statements. Given that, this descriptive, comparative, and predictive-causal research is focused on assessing the cognizance, understanding, and acceptance of the students of the VMGO of the college. Moreover, it intended to determine the gender and year level difference concerning VMGO. Finally, it is aimed to determine if cognizance can predict understanding and acceptance; cognizance can predict perceived clarity and consistency; perceived clarity and consistency predict understanding and acceptance. After surveying 364 BPEd students, a significant difference was observed in gender and year level based on cognizance of the VMGO and its clarity and consistency. Also, it was found that cognizance positively predicts understanding and acceptance; cognizance leverages perceived clarity and consistency; perceived clarity and consistency influence understanding and acceptance. Based on the findings, several recommendations were presented. Also, this study invites all other Local Colleges and Universities and HEIs to assess their operations, policies, and performance by conducting a similar study to provide new information in the discipline. In the culmination of this study, the findings discovered are a true testament to the college's genuine commitment to its primary stakeholders in the spirit of excellence, resiliency, stewardship, and patrimony.
A Comparison between External and Endonasal Dacryocystorhinostomy using the Lac-Q Questionnaire
Authors: Engelsberg Karl
Published: November 2022

Purpose
To assess lacrimal problems pre- and postoperatively with a symptom-based questionnaire (Lac-Q questionnaire), and to investigate patients’ satisfaction depending on their choice of surgical technique.
Methods
A total of 112 patients with lacrimal problems treated by external or endonasal dacryocystorhinostomy (DCR) were enrolled in the study. After surgery they were sent a symptom-based questionnaire (Lac-Q questionnaire) to evaluate their lacrimal symptoms pre- and postoperatively. Two complementary questions were added regarding the scar generated by the operation and their satisfaction with the operation.
Results
Pre-operative lacrimal problems, had high scores in the Lac-Q questionnaire. Patients expressed both symptomatic and social problems due to epiphora. The majority of the patients were satisfied after DCR surgery and no difference was found between the external DCR and endonasal DCR group concerning the degree of the patients’ satisfaction after the operation. A few patients were concerned about the scar after external DCR.
Conclusion
Lacrimal problems were regarded by the patients as a significant symptomatic and social burden. The relief of the symptoms and satisfaction after DCR operation were good regardless of the approach.
UNCERTAINTY QUANTIFICATION OF SELF-PROPULSION ANALYSES WITH RANS-CFD AND COMPARISON WITH FULL-SCALE SHIP TRIALS
Authors:   Piri Reis University, Turkey, Saydam Ahmet Ziya , Küçüksu Gözde Nur , İnsel Mustafa , Gökçay Serhan
Published: November 2022

RANS-CFD is a well-established tool with widespread use in maritime industry and research. Valuable information might be extracted from the results of such simulations in terms of ship resistance and flow field variables. With recent advancements in computational power, it became possible to investigate the performance of ships in self-propulsion conditions with RANS method. This paper presents the results of a study in which self-propulsion analyses of a small size product/oil tanker has been carried out at ship scale. The methodology proposed in this study makes use of open water propeller performance predictions, resistance analyses at model scale and self-propulsion computations at ship scale for a minimum of 2 different propeller loadings to obtain the self-propulsion point and respective performance parameters. In order to speed up the time-consuming self-propulsion computations, these cases have been solved with a single-phase approach. Resistance predictions have been compared with experimental findings. Uncertainty associated with prediction of resistance and thrust has been quantified. Additionally, sea trials have been conducted on the subject vessel and its two sisters and measured delivered power data have been used for evaluating the capability of the numerical method in self-propulsion predictions. Comparison of results indicate that the proposed self-propulsion computation methodology with RANS CFD at ship scale is capable of predicting delivered power with sufficient accuracy at an acceptable computational cost.
A 10-year critical review on hydrogen peroxide as a disinfectant: could it be an alternative for household water treatment?
Authors: Silva Kamila Jessie Sammarro , Sabogal-Paz Lyda Patricia
Published: November 2022

Considering that a large fraction of the global population relies on self-supplied drinking water systems, household water treatment (HWT) technologies may assist achieving the United Nations' Sustainable Development Goal 6.1, which aims at safe drinking water for all by 2030. Hydrogen peroxide disinfection has been widely known as an effective approach for microorganism inactivation, however, it has not been much explored as a standalone solution in sanitation. In this sense, this review presents systematically organized information extracted from papers on H2O2 disinfection from 2011 to 2021. Filtered data was analyzed by content and network visualization, raising a discussion on whether H2O2 could be a potential HWT intervention, and which limitations and prospects are there for its research and implementation. In short, we found a lack of consistency in operational conditions, as most of the retrieved studies address individual use of H2O2 as control to combined treatments. Additionally, oxidant demand and kinetics considering local water quality are lacking, as well as information on residual neutralization, toxicity, and up-scaling. This critical review reveals gaps that encourage further research tackling different disinfection challenges, so that this alternative can be evaluated for implementation as an HWT technology, particularly at context-specific situations.
Detection of beta-lactam antibiotic resistance in aquatic Enterobacteriaceae isolates
Authors: Zorbozan Hazal , Kimiran Ayten
Published: November 2022

Production of the beta-lactamase enzymes is the primary resistance mechanism caused by unconcious consumption of the beta-lactam group of antibiotics in Enterobacteriaceae. Combined disc tests were performed for extended-spectrum beta-lactamase (ESBL) confirmation (n = 15) and class C beta-lactamase (AmpC) confirmation (n = 6) after the disc diffusion test was applied in a total of 27 Enterobacteriaceae strains from Western Black Sea, Lake Manyas and Lake Iznik. Plasmid-mediated blaTEM, blaSHV, blaCTX-M , blaIMP genes, CIT, MOX, FOX gene groups and chromosomal blaAmpc gene of E. cloacae were investigated using the polymerase chain reaction (PCR). Three E. coli strains were shown to produce ESBL, while one E.coli and three E. cloacae strains were confirmed for AmpC production by disc tests. blaTEM (n = 2), blaSHV (n = 4), blaCTX-M (n = 2), blaTEM + blaSHV (n = 1), blaCTX-M + CIT (n = 1), blaSHV + CIT (n = 1) genes and/or gene groups were detected in 11 E. coli isolates; while blaSHV (n = 3) was observed in three Klebsiella strains (two K. oxytoca and one K. pneumoniae). With this study, the aquatic environments of Turkey were proved to be the reservoirs of antibiotic-resistance determinants of plasmid-mediated beta-lactamases in environmental wild-type bacteria transmitted by horizontal gene transfer.
Resolution of the Council of Expert Oncologists “Possibilities of immunotherapy with dinutuximab beta in the treatment of soft tissue and bone sarcomas in children” dated July 15, 2022, Moscow
Authors: Editorial Article
Published: November 2022

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Aplicação do método STAD na perspectiva do ensino contábil: grupos colaborativos e divisões de rendimento
Authors: Silva Joarlla de Medeiros Macedo , Ribeiro Gabriela Louise de Vasconcelos , Félix Tamara Pontes , Martins Joana Darc Medeiros
Published: November 2022

O presente estudo objetiva examinar a percepção dos mestrandos do Programa de Pós-Graduação em Ciências Contábeis da Universidade Federal do Rio Grande do Norte sobre a eficiência, aplicabilidade e competências do método colaborativo Student Teams Achievement Divisions (STAD) aplicado ao ensino da contabilidade, além de, buscar verificar, empiricamente, a eficiência do STAD aplicado à contabilidade ambiental. A pesquisa possui abordagem qualitativa e quantitativa, no formato de estudo de caso, cujos dados foram obtidos através de questionário aberto e observação participante. Com a finalidade de verificar a percepção dos discentes foi realizada análise de conteúdo por meio do Software ATLAS.ti 7®. O teste de hipótese T de Student foi utilizado para verificar a eficiência do método, enquanto o teste do Qui-quadrado verificou a relação entre a motivação do discente e a evolução da aprendizagem. Os resultados evidenciam que o STAD se demonstrou eficiente, haja vista a diferença estatisticamente significante entre as pontuações obtidas pelos discentes antes e após a aplicação do método. Foi verificado que, para a amostra estudada, a motivação do aluno não tem relação com o fato de o mesmo ter obtido êxito na pontuação alcançada. De acordo com a percepção dos mestrandos, o método é capaz de desenvolver habilidades interpessoais como comunicação, pensamento crítico e resolutividade de problemas. Ademais, o STAD estimulou o trabalho em equipe, que por sua vez motivou os discentes durante o desenvolvimento da aula.
Estudo qualitativo do preparo radicular durante instrumentação ultrassônica com diferentes limas
Authors: Cleber Keiti NABESHIMA  , Manoel Eduardo de Lima MACHADO  , Maria Letícia Borges BRITTO  , Raul Capp PALLOTTA
Published: November 2022

Introdução e objetivo: A proposta deste estudo foi verificar a qualidade de preparo da instrumentação ultrassônica influenciada por variados tipos de limas – K, K-flex e níquel-titânio – e diferentes marcas comerciais. Material e métodos: Foram divididos 30 blocos de canais simulados aleatoriamente em três grupos de acordo com o tipo de lima e a marca comercial, instrumentados pela técnica cervicoapical, com o terço apical preparado conforme a divisão. Resultados: Por meio da análise estatística foi possível observar que o grupo de limas K-flex FKG®, comparado aos grupos K FKG®, K Dentsply-Maillefer® e K-flex Dentsply-Maillefer®, obteve diferença estatisticamente significante. O grupo K-flex Dentsply-Maillefer® também demonstrou diferença em comparação com o grupo de níquel-titânio FKG®. Conclusão: O sistema ultrassônico pode causar alteração apical com dilaceração foraminal, e a marca comercial é capaz de influenciar no resultado final.
Expansão rápida da maxila cirurgicamente assistida sob anestesia local: relato de caso
Authors: João Frank Carvalho DANTAS  , Fabiano Pachêco de CARVALHO  , Iolanda Maria Cariry Carvalho L. BARROS  , Guilherme Romano SCARTEZINI  , Viviane Almeida SARMENTO
Published: November 2022

Introdução: A expansão rápida da maxila cirurgicamente assistida (ERMCA) é empregada para o tratamento das deficiências transversais verdadeiras em pacientes com maturidade esquelética, havendo uma associação entre o procedimento cirúrgico e o ortodôntico. Esse tratamento promove um aumento do perímetro do arco maxilar, o que melhora a acomodação da língua e corrige os corredores negros. O procedimento pode ser feito com anestesia local e é baixo o risco de complicações, tornando-se uma excelente alternativa de tratamento. Relato de caso e conclusão: Este artigo relata um caso de ERMCA, realizada sob anestesia local em ambiente ambulatorial. O paciente era portador de um quadro de deficiência transversal de maxila. A prática da ERMCA sob anestesia local em ambiente ambulatorial apresenta-se como um procedimento viável, de baixo custo, fácil execução e com riscos baixos, desde que seja executada conforme a técnica adequada.
Etiologia e prevenção das reabsorções cervicais externas associadas ao clareamento dentário
Authors: Eliane Mendes da SILVA  , Denise Piotto LEONARDI  , Gisele Aihara HARAGUSHIKU  , Flávia Sens Fagundes TOMAZINHO  , Flares BARATTO FILHO  , João César ZIELAK
Published: November 2022

Introdução e objetivo: A estética na Odontologia tem sido priorizada, e o desejo por dentes mais claros tem estado cada vez mais presente nos consultórios, pois dentes mais brancos tendem a demonstrar saúde, beleza, jovialidade e tornam o sorriso mais atraente. O clareamento dental é um meio conservador amplamente utilizado para restabelecer a cor natural de dentes escurecidos, no entanto uma provável relação com a reabsorção externa cervical tem preocupado muitos pesquisadores e clínicos. Revisão de literatura: Vários são os mecanismos que podem desencadear essa reabsorção, entre eles a ação química e física dos agentes clareadores empregados, a morfologia da junção amelocementária associada ao sistema imunológico, a concentração dos materiais empregados, os traumas, bem como a técnica de clareamento utilizada. Conclusão: Diante de diferentes fatores, ainda não conclusivos, prevenindo efeitos deletérios para dentes e estruturas de suporte, cuidados devem ser tomados na escolha do agente clareador, da técnica de aplicação e também dos casos, além da confecção de uma restauração adequada após o clareamento dental.
Tumor odontogênico ceratocístico
Authors: Alexandre Aires Braga de LIRA  , Belisse Brandão da CUNHA  , Hiarles Barreto Sampaio BRITO  , Gustavo Pina GODOY  , Lélia Maria Guedes QUEIROZ
Published: November 2022

Introdução: O tumor odontogênico ceratocístico (TOC) é uma lesão que requer considerações especiais por conta de seu comportamento clínico e de seus aspectos histopatológicos específicos. O presente estudo tem por objetivo apresentar um caso de TOC enfatizando suas características radiográficas e histopatológicas. Relato de caso: Paciente de 43 anos apresentou imagem radiolúcida unilocular localizada na região posterior do corpo mandibular, no lado esquerdo, estendendo-se até o ramo ascendente, observada em uma radiografia panorâmica. Foi submetida a um exame tomográfico seguido de biópsia incisional para posterior exame histopatológico, no qual foi observada cavidade patológica revestida por epitélio paraceratinizado, exibindo camada basal disposta em “paliçada” e que evidenciava células com hipercromatismo nuclear, confirmando tratar-se de um TOC. Conclusão: O conhecimento por parte dos cirurgiões-dentistas de lesões tumorais de natureza odontogênica, especialmente do TOC, é de fundamental importância, proporcionando assim um diagnóstico correto dessas lesões, evitando que elas assumam grandes dimensões e, por conseguinte, levem o paciente a uma mutilação significativa.
Proservação pós-operatória de paciente com Síndrome de Gorlin-Goltz – relato de caso
Authors: Alexsandra da Silva Botezeli STOLZ  , Marcia Oliva de OLIVEIRA  , Fabiana Vargas FERREIRA  , Celina Maria UGGERI
Published: November 2022

Introdução: A Síndrome de Gorlin-Goltz, também conhecida como Síndrome do Carcinoma Basocelular Nevoide, é um transtorno hereditário autossômico dominante que se caracteriza pela presença de ceratocistos múltiplos nos maxilares e carcinomas basocelulares, além de alterações musculoesqueléticas, neurológicas, dermatológicas e endócrinas. Relato de caso: O presente trabalho relata o caso de um paciente de 15 anos de idade, atendido na Faculdade de Odontologia da Universidade Federal de Santa Maria (RS), que apresentava ceratocistos múltiplos nos ossos maxilares, os quais foram removidos cirurgicamente em várias etapas. O paciente encontra-se em proservação de 48 meses, incluindo avaliações clínicas e radiográficas. Conclusão: Conclui-se que acompanhamento periódico e sistemático pode evitar consequências danosas ao paciente.
Avaliação da resistência de união em dentina humana submetida a diferentes formas de armazenagem
Authors: Ana Paula Jacob  , Mariana Ludwig Fraga  , Rubens Nazareno Garcia  , Luciano Madeira
Published: November 2022

Introdução e objetivo: Dentes humanos são frequentemente utilizados em atividades laboratoriais e nas pesquisas científicas. O objetivo deste estudo foi avaliar a resistência de união em dentina humana submetida a diferentes formas de armazenagem. Material e métodos:Foram selecionados 15 terceiros molares hígidos, divididos em três grupos experimentais (n = 5): 1) esterilizados em autoclave por 15 minutos (121°C) e congelados em água destilada por 60 dias; 2) imersos em solução de glutaraldeído 2% por 24 horas e congelados em água destilada por 60 dias; 3) somente congelados em água destilada por 60 dias (controle). As amostras foram preparadas com disco diamantado sob refrigeração para obtenção de superfícies planas de dentina média, que sofreram a ação de lixas de carbeto de silício n.º 600 para criar lama dentária previamente à hibridização. O sistema adesivo convencional Adper Single Bond 2 e o compósito Filtek Z250 (3M Espe) foram utilizados de acordo com as instruções dos fabricantes. Matrizes transparentes Tygon foram posicionadas sobre cada amostra de dentina hibridizada e preenchidas em seu volume interno com o compósito. Após fotoativação, removeram-se as matrizes e expuseram-se os corpos de prova, que foram armazenados em água destilada a 37°C por 24 horas antes do ensaio de resistência de união ao microcisalhamento. Resultados: A resistência de união foi calculada em MPa±DP, e os dados foram analisados estatisticamente pela Anova e pelo teste de Tukey no nível de 5% de significância. As informações obtidas mostraram que o grupo controle apresentou resistência de união estatisticamente superior aos demais grupos experimentais. Conclusão: A esterilização em autoclave e a imersão em solução de glutaraldeído reduziram de modo significativo a resistência de união em dentina humana, quando se comparou aos dentes armazenados em água destilada congelada.
Mecanismos e fatores fisiológicos e patológicos no processo de reabsorção radicular de dentes decíduos
Authors: Bianca Zimmermann Santos  , Vera Lúcia Bosco  , Juliana Yassue Barbosa da Silva  , Mabel Mariela Rodríguez Cordeiro
Published: November 2022

Introdução: A reabsorção dentária é fundamental no processo de rizólise (reabsorção radicular fisiológica) dos dentes decíduos, entretanto as reabsorções dentárias patológicas, especialmente a do tipo inflamatória, caracterizam-se em consequência e/ou complicação de várias situações clínicas, como traumatismos dentários e lesões periapicais inflamatórias provenientes da doença cárie, constituindo causa comum de perda de dentes. Objetivo: Procurou-se apresentar e discutir uma revisão de literatura acerca do mecanismo das reabsorções radiculares fisiológica e patológica inflamatória em dentes decíduos, enfatizando seus eventos bioquímicos e celulares. Revisão de literatura: As células responsáveis pela reabsorção dos tecidos dentais são os odontoclastos, sob a influência de inúmeros estímulos e sinalizações moleculares oriundos de citocinas, neuropeptídeos, hormônios e produtos de degradação liberados quando o tecido é lesado. Porém até hoje não se sabe exatamente o que leva à diferenciação das células precursoras dos odontoclastos, o que lhes dá o sinal para iniciar a reabsorção em local e momento específicos (principalmente nos dentes decíduos) e por que eles são prematuramente ativados em algumas condições patológicas, mas não em outras. Conclusão: O conhecimento sobre o mecanismo molecular e os fatores que regulam o processo de reabsorção radicular ainda é escasso. A pesquisa nessa área mostra-se de grande relevância, uma vez que novos conhecimentos sobre a(s) via(s) molecular(es) da reabsorção dental podem permitir o desenvolvimento de terapias diferenciadas, mais biológicas, que controlem ou impeçam a reabsorção, evitando assim a extração do dente acometido e suas consequências.
Fraturas nasais em esportes: sua ocorrência e importância
Authors: Neide Pena Coto  , Josete Barbosa Cruz Meira  , Reinaldo Brito e Dias
Published: November 2022

Introdução: O aumento do número de participantes nas mais variadas modalidades desportivas e de praticantes em recinto fechado trouxe também um aumento significativo de traumas orofaciais nos esportes, principalmente fraturas nasais, que ocupam o terceiro lugar em ocorrência em todas as modalidades desportivas. Objetivo e revisão de literatura: Trazer conhecimento das causas, da ocorrência e da importância da fratura nasal no esporte, já que é de responsabilidade do cirurgião-dentista confeccionar meios de proteção bucomaxilofaciais nos esportes, área em que a Odontologia do Esporte vem se sedimentando. Conclusão: Um afastamento prolongado do atleta acarreta a ele grande prejuízo físico e psicológico, assim como prejuízo financeiro para seu clube. Deve-se ter atenção para meios de proteção para o atleta.
Association of 25-Hydroxy Vitamin D with IL-17 Inflammatory Cytokines, and Osteoporosis in patients with Rheumatoid Arthritis in Kurdish nation / Iraq
Authors: Albarzinji Dr. Niaz , Albustany Dashty
Published: November 2022

Introduction:

Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. Lower Vitamin D (Vit. D) levels correlate with more severe clinical manifestations in RA and other rheumatic diseases. IL-17A promotes inflammation by inducing various proinflammatory cytokines and chemokines. In this study, we evaluated the association between Vitamin. D and IL-17 in osteoporosis in Rheumatoid Arthritis in Kurdish nation / Iraq.

Objective:

Blood samples from rheumatoid arthritis (RA) patients were used to measure the levels of the inflammatory cytokine IL-17 and the Vit. D precursor 25(OH)D and bone loss in patients with RA in this study.

Methods:

In this study, 40 healthy controls were included in the research, which comprised 100 new cases of RA. ELISA was used to measure the level of serum 25(OH)D and IL-17. Moreover, DXA was used to assess average bone mineral density (BMD).

Results:

We discovered no difference between the two groups in terms of age or gender. This means that compared to the control group, the 25(OH)D serum levels in the RA group were lower (P 0.01; 16.85+8.7 nmol/l vs. 39.95 (-+9.8)). IL-17 serum levels were highly and negatively associated with 25(OH)D levels in arthritic patients. A comparison of 25(OH)D levels in patients with osteoporosis and osteopenia and those with BMD was also performed.

Conclusion:

Bone loss and IL-17 have been associated with reduced Vit. D levels in patients with rheumatoid arthritis; a lack of Vit. D may have a role in developing the disease, according to the data presented in this study.
Biological Rhythms in People from North Macedonia with Bipolar Disorder: Application of the Macedonian Biological Rhythms Interview of Assessment in Neuropsychiatry (BRIAN)
Authors: Kalcev Goce , Barbov Ivan , Kotevska Pavlina Ilieska , Preti Antonio , Carta Mauro G.
Published: November 2022

Objective:

The Biological Rhythms Interview of Assessment in Neuropsychiatry (BRIAN) is a tool aimed at clinically evaluating disturbances in biological rhythm. In this study, we examined the reliability and validity of the Macedonian version of the BRIAN.

Methods:

A total of 100 participants, including 50 subjects with bipolar disorder (BD) and 50 control healthy subjects, were recruited. Construct validity was tested by comparing the mean BRIAN scores of the BD patients and control subjects.

Results:

No difference by gender or age was noticed, but patients differed from controls in education and occupation. Reliability, as measured with Cronbach’s alpha, was good in BD individuals, except for the Rhythms subscale. Reliability in controls was less good, especially for the Sleep and Rhythms subscales. The tool was able to discriminate patients with controls, with large differences on all subscales. However, since the reliability was suboptimal for some of these subscales, these differences cannot be entirely trusted.

Conclusion:

The study suggests that the Macedonian version of this instrument has good psychometric characteristics and also encourages the chance of developing mixed screening tools by incorporating elements of biological rhythm dysregulation into the routine evaluation of mood.
Improving the thermal properties of the device in the process of forming a contact with the collector region of a silicon transistor
Authors: Kazalieva E. , Shakhmaeva A. R.
Published: November 2022

Objective. The objective of the study is to increase the reliability of the contact of the semiconductor transistor crystal to the body and the reproducibility of the technological process.

Method. A method for obtaining multilayer metallization of the reverse side of the crystal has been developed and the most optimal technological modes of its formation have been selected. The parameters of the reliability of the connection of the crystal to the body of the transistor were checked.

Results. Layer-by-layer metallization has been obtained, which provides a strong contact to the collector region of the transistor and a reliable fit of the crystal to the base of the case.The control of technological operations showed 100% distribution of solder over the surface of the crystal, the absence of pores in the solder, the improvement in the output characteristics of the device and the increase in the percentage of output usable transistors.

Conclusion. An analysis of the experimental results showed that in order to create a reliable contact and remove heat from the collector junction of power semiconductor transistors on the reverse side of the plates, it is necessary to form a metallization in one technological cycle, consisting of four layers of metals (Cr-Ni-Sn-Ag). The technical result of the research is to improve the quality of fit by obtaining a uniform distribution of the layer of Cr-Ni-Sn-Ag metals in a single technological cycle.
La importancia de la biota edáfica en México
Authors: Fragoso Carlos , Reyes Castillo Pedro , Rojas Patricia
Published: November 2022

En los últimos años los estudios sobre la diversidad edáfica han cobrado mayor importancia. En México, sin embargo, se han publicado muy pocos trabajos enfocados a este tama y casi siempre descontextualizados del entorno edáfico. Como producto de varias reuniones celebradas en los últimos años, se logró conjuntar a un grupo de especialistas para publicar una síntesis del conocimiento de algunos organismos de la biota edáfica de México. Esta selección tomó en cuenta aquellos grupos con un fuerte potencial de manejo o con una participación clave en los procesos edáficos. En este trabajo se revisan las contribuciones de este número especial, tomando como marco conceptual el proceso de la descomposición y los organismos involucrados.
A Data-Based Reliability Analysis of ESP Failures in Oil Production Wells
Authors: AlBallam Shaikha , Karami Hamidreza , Devegowda Deepak
Published: November 2022

Electrical Submersible Pumps (ESPs) are one of the most widely used artificial lift methods in the petroleum industry. However, ESP failures are unanticipated and common occurrences with significant financial impacts for the operators. Analysis of the ESP performance and failures are essential in its design and optimization. This paper presents a statistical approach for diagnosing and evaluating the root causes of ESP failures. The analysis is based on the field data gathered from the surface and downhole ESP monitoring equipment over five years of production of 10 wells. Electrical failures are the most common general cause of ESP failures, accounting for 61% of all failures, followed by motor failure and gas locking. Specifically, power failure, under-voltage, voltage unbalance, and motor underload are the most common occurrences. The data trends are analyzed for the two weeks before each specific failure, and conclusions are made on the warning signs to predict failures. In addition, a Weibull statistical analysis model is constructed to evaluate the reliability features and estimate the ESP failure probability, allowing operators to perform preventive maintenance. The results provide guidelines for ESP operations and contribute to reducing or preventing ESP downtimes and operating costs.
Neuroprotective Potentials of Honey for Cerebral Small Vessel Disease
Authors: Che Mohd Nassir Che Mohd Nasril , Abdul Hamid Hafizah , Hambali Aqilah , Abd Manan Nizar , Mehat Muhammad Zulfadli , Ismail Nurul Iman , Mustapha Muzaimi
Published: November 2022

The nectar produced by bees in nature is known as honey and has been consumed for its nutritional and medicinal properties. There is growing evidence that honey and its compounds have anti-inflammatory, antioxidant and anti-microbial properties that are relevant to the maintenance of health and the prevention of illnesses, including cardiocerebrovascular disease. Cerebral small vessel disease (CSVD) is one of the major risk factors for diseases such as stroke, dementia, Alzheimer’s disease, and Parkinson’s disease. CSVD is prevalent with aging and the presence of vascular risk factors. Its most common deleterious effect on the brain parenchyma is a neurological problem, causing a spectrum of subtle clinical manifestations such as neurocognitive dysfunction, emotional or behavioral disturbances, and gait dysfunction. Moreover, the pathological mechanisms and preventive strategies for CSVD remain elusive, which is reflected in the continued lack of effective therapeutic and preventive therapies. Given the growing literature on honey and its compounds as a superfood-based preventive measure, this narrative review highlights the neuroprotective potentials of honey and its compounds in relation to the current understanding of CSVD pathomechanism.
Perspectives of Rare Disease Social Media Group Participants on Engaging With Genetic Counselors: Mixed Methods Study
Authors: Yabumoto Megan , Miller Emily , Rao Anoushka , Tabor Holly K , Ormond Kelly E , Halley Meghan C
Published: November 2022

Background

Social media provides a potential avenue for genetic counselors to address gaps in access to reliable genetics information for rare disease communities. However, only limited research has examined patient and family attitudes toward engaging with genetic counselors through social media.

Objective

Our study assessed the attitudes of members of rare disease social media groups toward engaging with genetic counselors through social media, characteristics associated with greater interest, and the benefits and potential pitfalls of various approaches to such engagement.

Methods

We conducted a mixed methods survey of patients and family members recruited from a systematic sample of rare disease Facebook groups. Patient characteristics and their associations with interest in engagement with genetic counselors were evaluated using univariate and bivariate statistics. Responses to open-ended questions were analyzed using thematic content analysis.

Results

In total, 1053 individuals from 103 rare disease groups participated. The median overall interest in engaging with genetic counselors on social media was moderately high at 7.0 (IQR 4.0-9.0, range 0-10). No past experience with a genetic counselor was associated with greater interest in engaging with one through social media (µ=6.5 vs 6.0, P=.04). Participants expressed greatest interest (median 9.0, IQR 5.0-10.0) in engagement models allowing direct communication with genetic counselors, which was corroborated by the majority (n=399, 61.3%) of individuals who responded to open-ended questions explicitly stating their interest in 1-on-1 interactions. When asked what forms of support they would request from genetic counselors through social media, participants desired individualized support and information about how to access services. However, participants also expressed concerns regarding privacy and confidentiality.

Conclusions

Patients and family members in rare disease social media groups appear interested in engaging with genetic counselors through social media, particularly for individualized support. This form of engagement on social media is not meant to replace the current structure and content of genetic counseling (GC) services, but genetic counselors could more actively use social media as a communication tool to address gaps in knowledge and awareness about genetics services and gaps in accessible patient information. Although encouraging, concerns regarding privacy and feasibility require further consideration, pointing to the need for professional guidelines in this area.
Physical Activity Surveillance in Children and Adolescents Using Smartphone Technology: Systematic Review (Preprint)
Authors: Nasruddin Nur Izzatun Nasriah , Murphy Joey , Armstrong Miranda Elaine Glynis
Published: November 2022

BACKGROUND

Self-reported physical activity (PA) questionnaires have traditionally been used for PA surveillance in children and adolescents, especially in free-living conditions. Objective measures are more accurate at measuring PA, but high cost often creates a barrier for their use in low- and middle-income settings. The advent of smartphone technology has greatly influenced mobile health and has offered new opportunities in health research, including PA surveillance.

OBJECTIVE

This review aimed to systematically explore the use of smartphone technology for PA surveillance in children and adolescents, specifically focusing on the use of smartphone apps.

METHODS

A literature search was conducted using 5 databases (PubMed, Scopus, CINAHL, MEDLINE, and Web of Science) and Google Scholar to identify articles relevant to the topic that were published from 2008 to 2023. Articles were included if they included children and adolescents within the age range of 5 to 18 years; used smartphone technology as PA surveillance; had PA behavioral outcomes such as energy expenditure, step count, and PA levels; were written in English; and were published between 2008 and 2023.

RESULTS

We identified and analyzed 8 studies (5 cross-sectional studies and 3 cohort studies). All participants were aged 12-18 years, and all studies were conducted in high-income countries only. Participants were recruited from schools, primary care facilities, and voluntarily. Five studies used mobile apps specifically and purposely developed for the study, whereas 3 studies used mobile apps downloadable from the Apple App Store and Android Play Store. PA surveillance using these apps was conducted from 24 hours to 4 weeks.

CONCLUSIONS

Evidence of PA surveillance using smartphone technology in children and adolescents was insufficient, which demonstrated the knowledge gap. Additional research is needed to further study the feasibility and validity of smartphone apps for PA surveillance among children and adolescents, especially in low- and middle-income countries.
Assessing the Readability of Patient Education Materials in Obstetrics and Gynecology (Preprint)
Authors: Wu Danny
Published: November 2022

BACKGROUND

TBD

OBJECTIVE

TBD

METHODS

TBD

RESULTS

TBD

CONCLUSIONS

TBD
Preferences of University Students for a Psychological Intervention Designed to Improve Sleep: Focus Group Study (Preprint)
Authors: Tadros Michelle , Li Sophie , Upton Emily , Newby Jill , Werner-Seidler Aliza
Published: November 2022

BACKGROUND

Many university students have difficulties with sleep; therefore, effective psychological treatments are needed. Most research on psychological treatments to improve sleep has been conducted with middle-aged and older adults, which means it is unclear whether existing psychological treatments are helpful for young adult university students.

OBJECTIVE

This study aimed to discover university student preferences for a psychological intervention to improve sleep quality.

METHODS

Focus groups were conducted over 3 stages to examine students’ views regarding content, format, and session duration for a psychological intervention to improve sleep. A thematic analysis was conducted to analyze participant responses.

RESULTS

In total, 30 participants attended small focus group discussions. Three key themes were identified: (1) program development, (2) help-seeking, and (3) student sleep characteristics. Program development subthemes were program format, program content, and engagement facilitators. Help-seeking subthemes were when to seek help, where to access help, stigma, and barriers. Student sleep characteristics subthemes were factors disturbing sleep and consequences of poor sleep.

CONCLUSIONS

Students emphasized the need for a sleep intervention with an in-person and social component, individualized content, and ways to monitor their progress. Participants did not think there was a stigma associated with seeking help for sleep problems. Students identified the lack of routine in their lifestyle, academic workload, and the pressure of multiple demands as key contributors to sleep difficulties.

CLINICALTRIAL
Low-Cost Technology-Aided Programs for Supporting People With Motor, Visual, and Intellectual Disabilities in Functional Forms of Occupation and Communication: Proof-of-Concept Study (Preprint)
Authors: Lancioni Giulio E , Singh Nirbhay N , O’Reilly Mark F , Sigafoos Jeff , Alberti Gloria , Chiariello Valeria , Desideri Lorenzo , Buono Serafino
Published: November 2022

BACKGROUND

People with motor, visual, and intellectual disabilities may have serious problems in independently accessing various forms of functional daily occupation and communication.

OBJECTIVE

The study was aimed at developing and assessing new, low-cost technology-aided programs to help people with motor or visual-motor and intellectual disabilities independently engage in functional forms of occupation and communication with distant partners.

METHODS

Two programs were set up using a smartphone interfaced with a 2-switch device and a tablet interfaced with 2 pressure sensors, respectively. Single-subject research designs were used to assess (1) the first program with 2 participants who were blind, had moderate hand control, and were interested in communicating with distant partners through voice messages; and (2) the second program with 2 participants who possessed functional vision, had no or poor hand control, and were interested in communicating with their partners through video calls. Both programs also supported 2 forms of occupational engagement, that is, choosing and accessing preferred leisure events consisting of songs and music videos, and listening to brief stories about relevant daily topics and answering questions related to those stories.

RESULTS

During the baseline phase (when only a conventional smartphone or tablet was available), 2 participants managed sporadic access to leisure or leisure and communication events. The other 2 participants did not show any independent leisure or communication engagement. During the intervention (when the technology-aided programs were used), all participants managed to independently engage in multiple leisure and communication events throughout the sessions and to listen to stories and answer story-related questions.

CONCLUSIONS

The findings, which need to be interpreted with caution given the nature of the study and the small number of participants, seem to suggest that the new programs may be viable tools for helping people with motor or visual-motor and intellectual disabilities independently access leisure, communication, and other forms of functional engagement.