bluuebunny/crossref_metadata_2025 huggingface dataset:
Heat Flow in the Western Arctic Ocean (Amerasian Basin)
Authors: Ruppel C. D. , Lachenbruch A. H. , Hutchinson D. R. , Munroe R. J. , Mosher D. C.
Published: July 2019

From 1963 to 1973 the U.S. Geological Survey measured heat flow at 356 sites in the Amerasian Basin (Western Arctic Ocean) from a drifting ice island (T‐3). The resulting measurements, which are unevenly distributed on Alpha‐Mendeleev Ridge and in Canada and Nautilus Basins, greatly expand available heat flow data for the Arctic Ocean. Average T‐3 heat flow is ~54.7 ± 11.3 mW/m2, and Nautilus Basin is the only well‐surveyed area (~13% of data) with significantly higher average heat flow (63.8 mW/m2). Heat flow and bathymetry are not correlated at a large scale, and turbiditic surficial sediments (Canada and Nautilus Basins) have higher heat flow than the sediments that blanket the Alpha‐Mendeleev Ridge. Thermal gradients are mostly near‐linear, implying that conductive heat transport dominates and that near‐seafloor sediments are in thermal equilibrium with overlying bottom waters. Combining the heat flow data with modern seismic imagery suggests that some of the observed heat flow variability may be explained by local changes in lithology or the presence of basement faults that channel circulating seawater. A numerical model that incorporates thermal conductivity variations along a profile from Canada Basin (thick sediment on mostly oceanic crust) to Alpha Ridge (thin sediment over thick magmatic units associated with the High Arctic Large Igneous Province) predicts heat flow slightly lower than that observed on Alpha Ridge. This, along with other observations, implies that circulating fluids modulate conductive heat flow and contribute to high variability in the T‐3 data set.
Characterizing the Self‐Potential Response to Concentration Gradients in Heterogeneous Subsurface Environments
Authors: MacAllister DJ. , Graham M. T. , Vinogradov J. , Butler A. P. , Jackson M. D.
Published: July 2019

Self‐potential (SP) measurements can be used to characterize and monitor, in real‐time, fluid movement and behavior in the subsurface. The electrochemical exclusion‐diffusion (EED) potential, one component of SP, arises when concentration gradients exist in porous media. Such concentration gradients are of concern in coastal and contaminated aquifers and oil and gas reservoirs. It is essential that estimates of EED potential are made prior to conducting SP investigations in complex environments with heterogeneous geology and salinity contrasts, such as the UK Chalk coastal aquifer. Here we report repeatable laboratory estimates of the EED potential of chalk and marls using natural groundwater (GW), seawater (SW), deionized (DI) water, and 5 M NaCl. In all cases, the EED potential of chalk was positive (using a GW/SW concentration gradient the EED potential was ca. 14 to 22 mV), with an increased deviation from the diffusion limit at the higher salinity contrast. Despite the relatively small pore size of chalk (ca. 1 μm), it is dominated by the diffusion potential and has a low exclusion efficiency, even at large salinity contrasts. Marl samples have a higher exclusion efficiency which is of sufficient magnitude to reverse the polarity of the EED potential (using a GW/SW concentration gradient the EED potential was ca. −7 to −12 mV) with respect to the chalk samples. Despite the complexity of the natural samples used, the method produced repeatable results. We also show that first order estimates of the exclusion efficiency can be made using SP logs, supporting the parameterization of the model reported in Graham et al. (2018, https://doi.org/10.1029/2018WR022972), and that derived values for marls are consistent with the laboratory experiments, while values derived for hardgrounds based on field data indicate a similarly high exclusion efficiency. While this method shows promise in the absence of laboratory measurements, more rigorous estimates should be made where possible and can be conducted following the experimental methodology reported here.
Author Correction: Semen levels of matrix metalloproteinase (MMP) and tissue inhibitor of metalloproteinases (TIMP) protein families members in men with high and low sperm DNA fragmentation
Authors: Belardin Larissa Berloffa , Antoniassi Mariana Pereira , Camargo Mariana , Intasqui Paula , Fraietta Renato , Bertolla Ricardo Pimenta
Published: July 2019

A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
The molecular nature of the 17β-Estradiol binding site in the voltage- and Ca2+-activated K+ (BK) channel β1 subunit
Authors: Granados Sara T. , Castillo Karen , Bravo-Moraga Felipe , Sepúlveda Romina V. , Carrasquel-Ursulaez Willy , Rojas Maximiliano , Carmona Emerson , Lorenzo-Ceballos Yenisleidy , González-Nilo Fernando , González Carlos , Latorre Ramón , Torres Yolima P.
Published: July 2019

The accessory β1 subunit modulates the Ca2+- and voltage-activated K+ (BK) channel gating properties mainly by increasing its apparent Ca2+ sensitivity. β1 plays an important role in the modulation of arterial tone and blood pressure by vascular smooth muscle cells (SMCs). 17β-estradiol (E2) increases the BK channel open probability (Po) in SMCs, through a β1 subunit-dependent modulatory effect. Here, using molecular modeling, bioinformatics, mutagenesis, and electrophysiology, we identify a cluster of hydrophobic residues in the second transmembrane domain of the β1 subunit, including the residues W163 and F166, as the binding site for E2. We further show that the increase in Po induced by E2 is associated with a stabilization of the voltage sensor in its active configuration and an increase in the coupling between the voltage sensor activation and pore opening. Since β1 is a key molecular player in vasoregulation, the findings reported here are of importance in the design of novel drugs able to modulate BK channels.
Neural Correlates of Variations in Human Trust in Human-like Machines during Non-reciprocal Interactions
Authors: Jung Eun-Soo , Dong Suh-Yeon , Lee Soo-Young
Published: July 2019

As intelligent machines have become widespread in various applications, it has become increasingly important to operate them efficiently. Monitoring human operators’ trust is required for productive interactions between humans and machines. However, neurocognitive understanding of human trust in machines is limited. In this study, we analysed human behaviours and electroencephalograms (EEGs) obtained during non-reciprocal human-machine interactions. Human subjects supervised their partner agents by monitoring and intervening in the agents’ actions in this non-reciprocal interaction, which reflected practical uses of autonomous or smart systems. Furthermore, we diversified the agents with external and internal human-like factors to understand the influence of anthropomorphism of machine agents. Agents’ internal human-likenesses were manifested in the way they conducted a task and affected subjects’ trust levels. From EEG analysis, we could define brain responses correlated with increase and decrease of trust. The effects of trust variations on brain responses were more pronounced with agents who were externally closer to humans and who elicited greater trust from the subjects. This research provides a theoretical basis for modelling human neural activities indicate trust in partner machines and can thereby contribute to the design of machines to promote efficient interactions with humans.
Statistical model choice including variable selection based on variable importance: A relevant way for biomarkers selection to predict meat tenderness
Authors: Ellies-Oury M. P. , Chavent M. , Conanec A. , Bonnet M. , Picard B. , Saracco J.
Published: July 2019

In this paper, we describe a new computational methodology to select the best regression model to predict a numerical variable of interest Y and to select simultaneously the most interesting numerical explanatory variables strongly linked to Y. Three regression models (parametric, semi-parametric and non-parametric) are considered and estimated by multiple linear regression, sliced inverse regression and random forests. Both the variables selection and the model choice are computational. A measure of importance based on random perturbations is calculated for each covariate. The variables above a threshold are selected. Then a learning/test samples approach is used to estimate the Mean Square Error and to determine which model (including variable selection) is the most accurate. The R package modvarsel (MODel and VARiable SELection) implements this computational approach and applies to any regression datasets. After checking the good behavior of the methodology on simulated data, the R package is used to select the proteins predictive of meat tenderness among a pool of 21 candidate proteins assayed in semitendinosus muscle from 71 young bulls. The biomarkers were selected by linear regression (the best regression model) to predict meat tenderness. These biomarkers, we confirm the predominant role of heat shock proteins and metabolic ones.
Predicted Impact of Climate Change on Trihalomethanes Formation in Drinking Water Treatment
Authors: Valdivia-Garcia Maria , Weir Paul , Graham David W. , Werner David
Published: July 2019

Quantitative predictions of impacts on public water supplies are essential for planning climate change adaptations. Monitoring data from five full-scale Scottish drinking water treatment plants (DWTPs) showed that significant correlations exist between conditionally carcinogenic trihalomethanes (THMs) levels, water temperature (r = 0.812, p = 0.0013) and dissolved organic carbon (DOC) (r = 0.892, p < 0.0001), respectively. The strong seasonality of these parameters demonstrated how climate can influence THMs formation. We quantified with laboratory experiments the sensitivity of THMs formation to changes in water temperature and DOC concentration. The laboratory data accurately reproduced real-world THM formation in the DWTPs. We then combined these validated relationships with information from the literature about future trends in mean summer temperatures and surface water DOC in the British Isles, to estimate future global warming impacts on THMs formation in DWTPs that use chlorine for disinfection. An increase in mean summer temperatures will likely increase THM formation, with a 1.8 °C temperature increase and 39% THMs increase by 2050 representing our mid-range scenario. Such an increase has major implications to potable water around the world, either an increased health risk or increased water treatment costs to maintain an equivalent quality potable supply.
Preparation of the heterojunction catalyst N-doping carbon quantum dots/P25 and its visible light photocatalytic activity
Authors: Xu Ning , Huang Hongqin , Ouyang Hao , Wang Huigang
Published: July 2019

N-doping carbon quantum dots were successfully loaded on P25 nanoparticles (denoted as N-CDs/P25) by facile hydrothermal process, and their morphology and chemical structure were systematically studied. The carrier of N-CDs can significantly broaden the photoresponse range of the P25 to the visible region, accelerate charge transportation and separation. Application of the N-CDs/P25 material for the photocatalytic decomposition of Rhodamine B (RhB) gave improved activity relative to P25. The best degradation activity obtained at 6mL N-CDs/P25 under visible light irradiation, which shows a 13.06 fold photocatalytic activity over P25. Radical trapping control experiment and Electron Paramagnetic Resonance (EPR) measurements have been applied to explore the photodegradation dynamic and visible-light driven degradation mechanism. This work provides new insights into the fabrication of N-doping carbon quantum dots/TiO2 composite and is promising to open new possibilities in the application of carbon-TiO2 composites as the photocatalysts in the environmental protection issues.
Identifying candidate genes for Phytophthora capsici resistance in pepper (Capsicum annuum) via genotyping-by-sequencing-based QTL mapping and genome-wide association study
Authors: Siddique Muhammad Irfan , Lee Hea-Young , Ro Na-Young , Han Koeun , Venkatesh Jelli , Solomon Abate Mekonnen , Patil Abhinandan Surgonda , Changkwian Amornrat , Kwon Jin-Kyung , Kang Byoung-Cheorl
Published: July 2019

Phytophthora capsici (Leon.) is a globally prevalent, devastating oomycete pathogen that causes root rot in pepper (Capsicum annuum). Several studies have identified quantitative trait loci (QTL) underlying resistance to P. capsici root rot (PcRR). However, breeding for pepper cultivars resistant to PcRR remains challenging due to the complexity of PcRR resistance. Here, we combined traditional QTL mapping with GWAS to broaden our understanding of PcRR resistance in pepper. Three major-effect loci (5.1, 5.2, and 5.3) conferring broad-spectrum resistance to three isolates of P. capsici were mapped to pepper chromosome P5. In addition, QTLs with epistatic interactions and minor effects specific to isolate and environment were detected on other chromosomes. GWAS detected 117 significant SNPs across the genome associated with PcRR resistance, including SNPs on chromosomes P5, P7, and P11 that colocalized with the QTLs identified here and in previous studies. Clusters of candidate nucleotide-binding site-leucine-rich repeat (NBS-LRR) and receptor-like kinase (RLK) genes were predicted within the QTL and GWAS regions; such genes often function in disease resistance. These candidate genes lay the foundation for the molecular dissection of PcRR resistance. SNP markers associated with QTLs for PcRR resistance will be useful for marker-assisted breeding and genomic selection in pepper breeding.
Superlattice in collapsed graphene wrinkles
Authors: Verhagen Tim , Pacakova Barbara , Bousa Milan , Hübner Uwe , Kalbac Martin , Vejpravova Jana , Frank Otakar
Published: July 2019

Topographic corrugations, such as wrinkles, are known to introduce diverse physical phenomena that can significantly modify the electrical, optical and chemical properties of two-dimensional materials. This range of assets can be expanded even further when the crystal lattices of the walls of the wrinkle are aligned and form a superlattice, thereby creating a high aspect ratio analogue of a twisted bilayer or multilayer – the so-called twisted wrinkle. Here we present an experimental proof that such twisted wrinkles exist in graphene monolayers on the scale of several micrometres. Combining atomic force microscopy and Raman spectral mapping using a wide range of visible excitation energies, we show that the wrinkles are extremely narrow and their Raman spectra exhibit all the characteristic features of twisted bilayer or multilayer graphene. In light of a recent breakthrough – the superconductivity of a magic-angle graphene bilayer, the collapsed wrinkles represent naturally occurring systems with tuneable collective regimes.
Defaunation of large-bodied frugivores reduces carbon storage in a tropical forest of Southeast Asia
Authors: Chanthorn Wirong , Hartig Florian , Brockelman Warren Y. , Srisang Wacharapong , Nathalang Anuttara , Santon Jantima
Published: July 2019

Recent studies have suggested that defaunation of large-bodied frugivores reduces above-ground carbon storage in tropical forests of South America and Africa, but not, or less so, in Southeast Asian tropical forests. Here we analyze the issue using the seed dispersal network (data of interaction between trees and animal seed dispersers) and forest composition of a 30-ha forest dynamics plot in central Thailand, where an intact fauna of primates, ungulates, bears and birds of all sizes still exists. We simulate the effect of two defaunation scenarios on forest biomass: 1) only primates extirpated (a realistic possibility in near future), and 2) extirpation of all large-bodied frugivores (LBF) including gibbons, macaques, hornbills and terrestrial mammals, the main targets of poachers in this region. For each scenario, we varied the population size reduction of the LBF dispersed tree species from 20% to 100%. We find that tree species dependent on seed dispersal by large-bodied frugivores (LBF) account for nearly one-third of the total carbon biomass on the plot, and that the community turnover following a complete defaunation would result in a carbon reduction of 2.4% to 3.0%, depending on the defaunation scenario and the model assumptions. The reduction was always greater than 1% when the defaunation intensity was at least 40%. These effect sizes are comparable to values reported for Neotropical forests, suggesting that the impact of defaunation on carbon deficit is not necessarily lower in Southeast Asian forests. The problem of defaunation in Asia, and the mutual benefits between biodiversity conservation and climate change mitigation, should therefore not be neglected by global policies to reduce carbon emissions.
Precursor RNA processing 3 is required for male fertility, and germline stem cell self-renewal and differentiation via regulating spliceosome function in Drosophila testes
Authors: Chen Xia , Luan Xiaojin , Zheng Qianwen , Qiao Chen , Chen Wanyin , Wang Min , Yan Yidan , Xie Bing , Shen Cong , He Zeyu , Zhang Jun , Liu Mingxi , Hu Xing , Li Hong , Zheng Bo , Fang Jie , Yu Jun
Published: July 2019

The nuclear pre-mRNA spliceosome is a large complex containing five small nuclear ribonucleoprotein particles (snRNPs) and many splicing factors. Messenger RNAs (mRNAs) are generated from pre-mRNAs by the process of RNA splicing, which is conserved in eukaryotes. Precursor RNA processing 3 (Prp3) is a U4/U6-associated snRNP whose function remains largely unknown. In the present study, using genetic manipulation of aDrosophila melanogastertestis model, we demonstrated thatPrp3is essential for male fertility inDrosophila.Prp3deficiency in germline stem cells (GSCs) and early cyst cells resulted in abnormal structure of testes and maintenance defects of GSCs and cyst stem cells. Knockdown ofPrp3in spermatogonia and early cyst cells mediated tumor formation caused by differentiation defects. Using anin vitroassay, knockdown ofPrp3decreased proliferation and increased cell death, and controlled the spliceosome function via regulating spliceosome subunits expression inDrosophilaS2 cells. We also identified two other splicing factors in the Prp complex (Prp19andPrp8), which mimicked the phenotype ofPrp3in theDrosophilastem cell niche. Our results revealed a significant role of precursor RNA processing factors in male testes, indicating that Prp3, a key spliceosome component in the Prp complex, is essential for male fertility, and germline stem cell self-renewal and differentiation, via regulating the spliceosome function inDrosophilatestes.
Anti-cancer activity of the novel 2-hydroxydiarylamide derivatives IMD-0354 and KRT1853 through suppression of cancer cell invasion, proliferation, and survival mediated by TMPRSS4
Authors: Kim Solbi , Ko Dongjoon , Lee Yunhee , Jang Seonghui , Lee Younghoon , Lee Ill Young , Kim Semi
Published: July 2019

Elevated expression of transmembrane serine protease 4 (TMPRSS4) correlates with poor prognosis in non-small cell lung cancer, gastric cancer, colorectal cancer, prostate cancer, and other cancer patients. Previously, we demonstrated that TMPRSS4 mediates tumor cell invasion, migration, proliferation, and metastasis. In addition, we reported novel 2-hydroxydiarylamide derivatives, IMD-0354 and KRT1853, as TMPRSS4 serine protease inhibitors. Here, we further evaluated the effects of the representative derivatives on TMPRSS4-mediated cellular function and signaling. IMD-0354 and KRT1853 inhibited cancer cell invasion, migration, and proliferation in TMPRSS4-expressing prostate, colon, and lung cancer cells. Both compounds suppressed TMPRSS4-mediated induction of Sp1/3, AP-1, and NF-κB transcription factors. Furthermore, TMPRSS4 promoted cancer cell survival and drug resistance, and both compounds enhanced anoikis sensitivity as well as reduced bcl-2 and survivin levels. Importantly, KRT1853 efficiently reduced tumor growth in prostate and colon cancer xenograft models. These results strongly recommend KRT1853 for further development as a novel anti-cancer agent.
Myocardial hypothermia increases autophagic flux, mitochondrial mass and myocardial function after ischemia-reperfusion injury
Authors: Marek-Iannucci Stefanie , Thomas Amandine , Hou Jean , Crupi Annunziata , Sin Jon , Taylor David J. , Czer Lawrence S. , Esmailian Fardad , Mentzer Robert M. , Andres Allen M. , Gottlieb Roberta A.
Published: July 2019

Animal studies have demonstrated beneficial effects of therapeutic hypothermia on myocardial function, yet exact mechanisms remain unclear. Impaired autophagy leads to heart failure and mitophagy is important for mitigating ischemia/reperfusion injury. This study aims to investigate whether the beneficial effects of therapeutic hypothermia are due to preserved autophagy and mitophagy. Under general anesthesia, the left anterior descending coronary artery of 19 female farm pigs was occluded for 90 minutes with consecutive reperfusion. 30 minutes after reperfusion, we performed pericardial irrigation with warm or cold saline for 60 minutes. Myocardial tissue analysis was performed one and four weeks after infarction. Therapeutic hypothermia induced a significant increase in autophagic flux, mitophagy, mitochondrial mass and function in the myocardium after infarction. Cell stress, apoptosis, inflammation as well as fibrosis were reduced, with significant preservation of systolic and diastolic function four weeks post infarction. We found similar biochemical changes in human samples undergoing open chest surgery under hypothermic conditions when compared to the warm. These results suggest that autophagic flux and mitophagy are important mechanisms implicated in cardiomyocyte recovery after myocardial infarction under hypothermic conditions. New therapeutic strategies targeting these pathways directly could lead to improvements in prevention of heart failure.
Robust Formation of Ultrasmall Room-Temperature Neél Skyrmions in Amorphous Ferrimagnets from Atomistic Simulations
Authors: Ma Chung Ting , Xie Yunkun , Sheng Howard , Ghosh Avik W. , Poon S. Joseph
Published: July 2019

Neél skyrmions originate from interfacial Dzyaloshinskii Moriya interaction (DMI). Recent studies have explored using thin-film ferromagnets and ferrimagnets to host Neél skyrmions for spintronic applications. However, it is unclear if ultrasmall (10 nm or less) skyrmions can ever be stabilized at room temperature for practical use in high density parallel racetrack memories. While thicker films can improve stability, DMI decays rapidly away from the interface. As such, spins far away from the interface would experience near-zero DMI, raising question on whether or not unrealistically large DMI is needed to stabilize skyrmions, and whether skyrmions will also collapse away from the interface. To address these questions, we have employed atomistic stochastic Landau-Lifshitz-Gilbert simulations to investigate skyrmions in amorphous ferrimagnetic GdCo. It is revealed that a significant reduction in DMI below that of Pt is sufficient to stabilize ultrasmall skyrmions even in films as thick as 15 nm. Moreover, skyrmions are found to retain a uniform columnar shape across the film thickness due to the long ferrimagnetic exchange length despite the decaying DMI. Our results show that increasing thickness and reducing DMI in GdCo can further reduce the size of skyrmions at room temperature, which is crucial to improve the density and energy efficiency in skyrmion based devices.
Fatty acid desaturase 2 is up-regulated by the treatment with statin through geranylgeranyl pyrophosphate-dependent Rho kinase pathway in HepG2 cells
Authors: Tanaka Shou , Ishihara Noriko , Suzuki Sawako , Watanabe Yasuhiro , Nagayama Daiji , Yamaguchi Takashi , Ohira Masahiro , Saiki Atsuhito , Tanaka Tomoaki , Tatsuno Ichiro
Published: July 2019

Statins have been reported to increase the plasma concentration of arachidonic acid (AA), an omega-6 long chain polyunsaturated fatty acid (LCPUFA) in several clinical studies indicating that statins affect the endogenous synthesis of LCUFAs. In the present study, we investigated the roles of the intrinsic mevalonate cascade and Rho-dependent pathway in LCPUFA synthesis, especially focusing on fatty acid desaturases (Fads) 2, using the human hepatocellular carcinoma cell line HepG2. Cell number and the activity of caspase-3 and 7 (caspase-3/7) was measured using a commercial kit. Gene expression was analyzed by quantitative real-time PCR. Protein expression was detected by Western blot analysis. Atorvastatin decreased cell viability and increased caspase-3/7 activity in a dose-dependent manner. At lower concentrations, atorvastatin stimulated both mRNA and protein expression of Fads2, and increased mRNA expression of FADS1 and ELVOL5. Both mevalonate and geranylgeranyl-pyrophosphate (GGPP), but not cholesterol, fully reversed atorvastatin-induced upregulation of Fads2, and mevalonate-effected reversal was inhibited by treatment with the Rho-associated protein kinase inhibitor Y-27632. These data clearly demonstrated that in human HepG2 cells, statins affect the endogenous synthesis of LCPUFAs by regulation of not only Fads2, but also Fads1 and Elovl5, through the GGPP-dependent Rho kinase pathway.
A new strategy for the in vitro selection of stapled peptide inhibitors by mRNA display
Authors: Iqbal Emil S. , Richardson Stacie L. , Abrigo Nicolas A. , Dods Kara K. , Osorio Franco H. Estheban , Gerrish Heather S. , Kotapati Hari Kiran , Morgan Iain M. , Masterson Douglas S. , Hartman Matthew C. T.
Published: July 2019

α-methyl Cys incorporation plus cyclization allows for the creation of α-helical libraries by mRNA display.
Electricity production and the analysis of the anode microbial community in a constructed wetland-microbial fuel cell
Authors: Wang Guozhen , Guo Yating , Cai Jiaying , Wen Hongyu , Mao Zhen , Zhang Hao , Wang Xin , Ma Lei , Zhu Mengqin
Published: July 2019

The objective of this study is to assess bioelectricity generation, pollutant removal and the bacterial communities on anodes in constructed wetlands coupled with microbial fuel cells, through feeding the systems with three different types of synthetic wastewater.
Raman spectroscopy as a potential tool for label free therapeutic drug monitoring in human serum: the case of busulfan and methotrexate
Authors: Parachalil Drishya Rajan , Commerford Deirdre , Bonnier Franck , Chourpa Igor , McIntyre Jennifer , Byrne Hugh J.
Published: July 2019

A methodology is proposed, based on Raman spectroscopy coupled with multivariate analysis, to determine the Limit of Detection (LOD) and Limit of Quantification (LOQ) for therapeutic drug monitoring in human serum, using the examples of Busulfan and Methotrexate.
Flavonoids induce cell death in Leishmania amazonensis: in vitro characterization by flow cytometry and Raman spectroscopy
Authors: Araújo Morgana V. , Queiroz Aline C. , Silva João F. M. , Silva Amanda E. , Silva João K. S. , Silva Girliane R. , Silva Elaine C. O. , Souza Samuel T. , Fonseca Eduardo J. S. , Camara Celso A. , Silva Tania M. S. , Alexandre-Moreira Magna S.
Published: July 2019

The present study investigated gossypetin 3,7,8,4′-tetra-O-methyl ether (1) and kaempferol 3,7-di-O-methyl ether (3) which showed significant leishmanicidal activity without toxic effects to host cells.
Assessing utility of handheld laser induced breakdown spectroscopy as a means ofDalbergiaspeciation
Authors: Celani Caelin P. , Lancaster Cady A. , Jordan James A. , Espinoza Edgard O. , Booksh Karl S.
Published: July 2019

SevenDalbergiaand twonon-Dalbergiahardwood species were successfully differentiated with PLS-DA and KNN chemometric models of LIBS spectra.
Light-enhanced sponge-like carbon nanozyme used for synergetic antibacterial therapy
Authors: Xi Juqun , Wei Gen , Wu Qiuwen , Xu Zhilong , Liu Yingwei , Han Jie , Fan Lei , Gao Lizeng
Published: July 2019

A catalytic-photothermal synergetic antibacterial strategy based on a sponge-like carbon nanozyme was constructed for anti-infective defense.
Synthesis of supramolecular gels based on electron-transfer reactions between clay nanotubes and styrene
Authors: Zheng Jingqi , Ou Xianfeng , Wu Fan , Liu Mingxian
Published: July 2019

A novel supramolecular gel is synthesized using styrene and halloysite nanotubes under ultrasound treatment, in which the nanotubes act as gelators for the styrene gel.
Carba-closo-dodecaboranylethynyl ligands facilitating luminescent reversed charge-transfer excited states in gold/silver complexes
Authors: Hailmann Michael , Hupp Benjamin , Himmelspach Alexander , Keppner Fabian , Hennig Philipp T. , Bertermann Rüdiger , Steffen Andreas , Finze Maik
Published: July 2019

Homo- and heterometallic gold(i) and silver(i) complexes with the carba-closo-dodecaboranylethynyl ligand were obtained and the participation of the boron cluster to the photophysical properties was proven.
Mechano-responsive luminescent emissions of an organic molecular crystal: effects of aromatic stacking interactions and solid state packing
Authors: Devi Kakali , Sarma Rupam J.
Published: July 2019

Three polymorphs of 2-hydroxynaphthaldehyde semicarbazone (2-NOH-S) have been identified, and their mechano-responsive luminescent emissions and interconversions are discussed.
Effect of arrangement of functional groups on stability and gas adsorption properties in two regioisomeric copper bent diisophthalate frameworks
Authors: Xu Tingting , Jiang Zhenzhen , He Minghui , Gao Xiaoxia , He Yabing
Published: July 2019

The substituent's arrangement was found to have a significant effect on the structural stabilities and thus gas adsorption properties of the resultant MOFs.
Dry reforming activity due to ionic Ru in La1.99Ru0.01O3: the role of specific carbonates
Authors: Gangwar Bhanu P. , Pentyala Phanikumar , Tiwari Khushubo , Biswas Krishanu , Sharma Sudhanshu , Deshpande Parag A.
Published: July 2019

Dry reforming of methane was carried out over La2−2xRu2xO3 (x = 0.005, 0.01). Substitution of just 0.5 atom% of Ru in La2O3 enhanced the activity by 20 times in terms of conversion when compared to the activity exhibited by La2O3.
Rotational spectroscopy of organophosphorous chemical agents: cresyl and phenyl saligenin phosphates
Authors: Saragi Rizalina Tama , Juanes Marcos , Abad José Luis , Lesarri Alberto , Pinacho Ruth , Rubio José Emiliano
Published: July 2019

Cresyl and phenyl saligenin phosphate have been probed in a jet expansion by broadband chirp-excitation microwave spectroscopy, revealing the most stable confirmations and their structural properties.
Enhancement of propene oligomerization and aromatization by proximate protons in zeolites; FTIR study of the reaction pathway in ZSM-5
Authors: Tabor Edyta , Bernauer Milan , Wichterlová Blanka , Dedecek Jiri
Published: July 2019

The enhanced effect of strongly acidic proximate protons (distance 5.0–5.5 Å) in ZSM-5 was presented on complex propene oligomerization up to the aromatization and development of individual carbenium ion intermediates in the zeolite pores.
Correction: Efficient oxygen evolution on mesoporous IrOx nanosheets
Authors: Jiang Bo , Kim Jeonghun , Guo Yanna , Wu Kevin C. W. , Alshehri Saad M. , Ahamad Tansir , Alhokbany Norah , Henzie Joel , Yamauchi Yusuke
Published: July 2019

Correction for ‘Efficient oxygen evolution on mesoporous IrOx nanosheets’ by Bo Jiang et al., Catal. Sci. Technol., 2019, DOI: 10.1039/c9cy00302a.
Correction: Static phase transfer catalysis for Williamson reactions: pickering interfacial catalysis
Authors: Zhao Qiangqiang , Zhao Xiao , Peng Hui , Liu Yang , Yang Lihui , Sun Jie , Yang Lei , Shen Yifeng
Published: July 2019

Correction for ‘Static phase transfer catalysis for Williamson reactions: pickering interfacial catalysis’ by Qiangqiang Zhao et al., Catal. Sci. Technol., 2019, 9, 3445–3453.
Reactions of α-haloacroleins with azides: highly regioselective synthesis of formyl triazoles
Authors: Zhang Dongsheng , Fan Yingzhu , Yan Zhongliang , Nie Yi , Xiong Xingquan , Gao Lizhu
Published: July 2019

A metal-free route to 1,4-disubstituted and 1,4,5-trisubstituted formyl triazoles was developed. One 1,2,3-triazole containing diastereotopic protons was identified.
Microwave-assisted laser induced breakdown molecular spectroscopy: quantitative chlorine detection
Authors: Wakil M. A. , Alwahabi Zeyad T.
Published: July 2019

A 47 ± 7 μg. g−1 detection limit of chlorine in cement has been recorded, using microwave-assisted laser induced breakdown spectroscopy.
An ultra-high H2S-resistant gold-based imidazolium ionic liquid catalyst for acetylene hydrochlorination
Authors: Yue Yuxue , Wang Bolin , Sheng Gangfeng , Lai Huixia , Wang Saisai , Chen Zhi , Hu Zhong-Ting , Zhao Jia , Li Xiaonian
Published: July 2019

Enhancement of the sulfur resistance of gold-based catalysts is significantly relevant and highly desirable for the development and large-scale applications of these catalysts.
Mechanism of non-enzymatic antiglycation action by coumarin: a biophysical study
Authors: Abul Qais Faizan , Ahmad Iqbal
Published: July 2019

Coumarin inhibited non-enzymatic glycation by masking the free amino groups and scavenging carbonyl groups of protein.
Structural distortion induced ferromagnetism in two-dimensional metal-free graphitic-C3N4nanosheets
Authors: Gao Chenyang , Xia Baorui , Gao Daqiang , Liu Yonggang
Published: July 2019

Through controllable structural distortion engineering introduced by post-heat-treatment in the experiment, ferromagnetism is observed in g-C3N4.
Polymer of intrinsic microporosity-based macroporous membrane with high thermal stability as a Li-ion battery separator
Authors: Tian Yangyang , Lin Chong , Wang Zhenggong , Jin Jian
Published: July 2019

A PIM-1 macroporous membrane was successfully fabricated and used as a separator of rechargeable Li-ion batteries for the first time.
Synthesis of 1,4,5,6-tetrahydropyridazines and pyridazinesviatransition-metal-free (4 + 2) cycloaddition of alkoxyallenes with 1,2-diaza-1,3-dienes
Authors: Wu Qi , Shao Pan-Lin , He Yun
Published: July 2019

We developed an economical and practical protocol for the synthesis of 1,4,5,6-tetrahydropyridazines and pyridazinesviacyclization of alkoxyallenes and 1,2-diaza-1,3-dienes.
Effects of water, ammonia and formic acid on HO2 + Cl reactions under atmospheric conditions: competition between a stepwise route and one elementary step
Authors: Zhang Tianlei , Zhang Yongqi , Wen Mingjie , Tang Zhuo , Long Bo , Yu Xiaohu , Zhao Caibin , Wang Wenliang
Published: July 2019

The effects of acidic (FA), neutral (WM) and basic (AM) catalysts on the energetic and kinetic aspects of the HO2 + Cl reaction have been studied. At 298 K, the catalytic order of FA, WM and AM is WM > FA > AM.
Expeditious synthesis and preliminary antimicrobial activity of deflazacort and its precursors
Authors: Esposito Anna , De Gregorio Eliana , De Fenza Maria , D'Alonzo Daniele , Satawani Anil , Guaragna Annalisa
Published: July 2019

Synthesis of deflazacort: unexpected antibacterial activity of its epoxide synthetic precursor.
High electrostrictive properties and energy storage performances with excellent thermal stability in Nb-doped Bi0.5Na0.5TiO3-based ceramics
Authors: Wu Yichen , Wang Genshui , Jiao Zheng , Fan Yuzhu , Peng Ping , Dong Xianlin
Published: July 2019

Lowering Td to enlarge the temperature range between Td and the maximum dielectric temperature (Tm) proved to be an effective strategy to enhance the thermal stability strain and energy storage properties in BNT-based ceramics.
Copper-catalyzed synthesis of phenol and diaryl ether derivatives via hydroxylation of diaryliodoniums
Authors: Ye Lianbao , Han Chao , Shi Peiqi , Gao Wei , Mei Wenjie
Published: July 2019

A copper-catalysed hydroxylation of diaryliodoniums to generate phenols and diaryl ethers allows the synthesis of diversely functionalized phenols under mild reaction conditions and prepares diaryl ethers in a one-pot operation.
Correction: Cytotoxic trichothecene-type sesquiterpenes from the sponge-derived fungus Stachybotrys chartarum with tyrosine kinase inhibition
Authors: Li Yong , Liu Dong , Cheng Zhongbin , Proksch Peter , Lin Wenhan
Published: July 2019

Correction for ‘Cytotoxic trichothecene-type sesquiterpenes from the sponge-derived fungus Stachybotrys chartarum with tyrosine kinase inhibition’ by Yong Li et al., RSC Adv., 2017, 7, 7259–7267.
Metallic tungsten carbide nanoparticles as a near-infrared-driven photocatalyst
Authors: Huang Weicheng , Meng Hongxue , Gao Yan , Wang Jinxin , Yang Chunyu , Liu Danqing , Liu Jian , Guo Chongshen , Yang Bin , Cao Wenwu
Published: July 2019

In this study, we present the LSPR effect and full spectrum photoabsorption of metallic WC for the direct NIR-driven photoelectric conversion and photocatalytic degradation of organic pollutants.
Selective sacrificial metal–organic frameworks: a highly quantitative colorimetric naked-eye detector for aluminum ions in aqueous solutions
Authors: Rouhani Farzaneh , Rafizadeh-Masuleh Fatemeh , Morsali Ali
Published: July 2019

The detection, differentiation, and especially visual quantification of target compounds are important and interesting challenges for researchers.
IL-induced formation of dynamic complex iodide anions in IL@MOF composites for efficient iodine capture
Authors: Tang Yuanzhe , Huang Hongliang , Li Jian , Xue Wenjuan , Zhong Chongli
Published: July 2019

IL-induced formation of dynamic complex iodide anions in IL@MOF composites facilitates record iodine adsorption capacities for both iodine vapor and solution.
Mesoporous aluminium manganese cobalt oxide with pentahedron structures for energy storage devices
Authors: Wu Chun , Zhu Ying , Guan Cao , Jia Chuankun , Qin Wei , Wang Xianyou , Zhang Kaili
Published: July 2019

A porous pentahedron structured Al–Mn–Co ternary oxide (AMCO) grown on nickel foam with high asymmetric supercapacitive performance has been achieved.
Insights into constitutional isomeric effects on donor–acceptor intermolecular arrangements in non-fullerene organic solar cells
Authors: Lee Jungho , Go Eun Min , Dharmapurikar Satej , Xu Jianqiu , Lee Sang Myeon , Jeong Mingyu , Lee Kyu Cheol , Oh Jiyeon , Cho Yongjoon , Zhang Chunfeng , Xiao Min , Kwak Sang Kyu , Yang Changduk
Published: July 2019

The novel constitutional isomeric acceptors (o-F-ITIC and m-F-ITIC) are developed and they show the huge disparity of intermolecular interactions and/or arrangements with the donor polymer leading a significant variation in PCE of OSCs.
A biomimetic hybrid material consisting of CaCO3 mesoporous microspheres and an alternating copolymer for reversed-phase HPLC
Authors: Mochida Mai , Nagai Yuta , Kumagai Hiroto , Imai Hiroaki , Citterio Daniel , Hiruta Yuki
Published: July 2019

Inspired by egg shells, amphiphilic copolymer-modified monodisperse mesoporous CaCO3 microspheres were applied as a separation material.
Solvent-controlled and solvent-dependent strategies for the synthesis of multicolor carbon dots for pH sensing and cell imaging
Authors: Bai Jianliang , Ma Yusha , Yuan Guojun , Chen Xu , Mei Jing , Zhang Lu , Ren Lili
Published: July 2019

Solvent-controlled, pH-dependent and solvent-dependent strategies are proposed to obtain multicolor carbon dots using the same precursor.
D–A3 TADF emitters: the role of the density of states for achieving faster triplet harvesting rates
Authors: Eng Julien , Hagon Jerry , Penfold Thomas James
Published: July 2019

A D–A3 structure is used to enhance the triplet harvesting rate of a purely organic molecule. However, excited state symmetry breaking dynamics plays an detrimental role causing localisation of the electronic structure and reducing this rate.
Improving the efficiencies of small molecule solar cells by solvent vapor annealing to enhance J-aggregation
Authors: Xiao Liangang , Li Zhengdong , Hu Qin , Liu Yawei , Zhong Wenkai , Mei Xueli , Russell Thomas P. , Liu Yi , Min Yong , Peng Xiaobin , Cao Yong
Published: July 2019

The enhanced J-aggregation increases the crystallinity of the small molecules and forms a favorable film morphology with a fiber-like structure.
Long non-coding RNA SNHG5 promotes glioma progression via miR-205/E2F3 axis
Authors: Li Xiaojian , Liu Liang , Luo Yidan , Cui Sitong , Chen Wei , Zeng Ailiang , Shi Yan , Luo Liangsheng
Published: July 2019

In recent years, many studies have reported on the abnormal expression and correlation of long non-coding RNAs (lncRNAs) in tumours. However, the accurate molecular mechanism of lncRNAs in glioma is still in its infancy. In the present study, we aimed to explore the molecular mechanism of small nucleolar RNA host gene 5 (SNHG5) in glioma progression. First, we found that SNHG5 expression was higher in glioma and was related to glioma glucose uptake, migration and invasion. Second, through a series of assays, we concluded that SNHG5 acts as a sponge for miR-205, which inhibits tumour growth in glioma by targeting E2F transcription factor 3 (E2F3). Third, using a xenograft mouse model, we demonstrated that SNHG5 regulates tumourigenesis in vivo. Taken together, our results show that the SNHG5/miR-205/E2F3 axis is involved in glioma progression and may provide a new therapeutic target for the diagnosis and therapy of glioma.
Dc‐link voltage stability analysis technique for hybrid five‐phase open‐end winding drives
Authors: Darijevic Milan , Jones Martin , Levi Emil
Published: July 2019

The dc‐link voltage stability for a hybrid five‐phase open‐end winding (OeW) drive operating under carrier‐based pulse‐width modulation is studied. The drive consists of a five‐phase induction machine, supplied using one three‐level and one two‐level voltage source inverter. This configuration is analysed for the case of isolated dc‐link rails, while the dc‐link voltage ratio is considered as an additional degree of freedom. It is demonstrated that different dc‐link voltage ratios lead to the different overall number of voltage levels across stator windings. Modulation strategies are investigated and their performances are analysed from the dc‐link voltages stability point of view. An analytical method for dc‐link voltage stability analysis is presented. Results show that the four‐level configuration always leads to stable dc‐link voltages, regardless of the modulation strategy. On the other hand, if the six‐level configuration is combined with modulation strategies that lead to optimal harmonic performance, not all dc‐link capacitor voltages will be in the balance depending on the operating conditions.
Facile phyto‐mediated synthesis of gold nanoparticles using Eupatorium odoratum leaf extract and its size‐dependent catalytic activity
Authors: Roy Alok , Mohanta Bidhan
Published: July 2019

In this work, gold nanoparticles have been prepared using the leaf extract of Eupatorium odoratum assisted with microwave irradiation. The role of pH on the synthesis of gold nanoparticles has also been studied. At higher value of pH, size of nanoparticles got highly diminished, going below 10 nm. A probable mechanism of formation of such small nanoparticles has been proposed in this Letter. The effects of different parameters such as reaction time, temperature and pH variation on the final morphology of gold nanoparticles have been investigated. The characterisation of the samples has been carried out by transmission electron microscope, UV–Vis absorption spectroscope, Fourier transform infrared spectroscope and zeta potential analysis. Further, a comparative study of catalytic activity of gold nanoparticles of two different sizes was performed by monitoring the reduction of 2,4,6‐trinitrophenol. Experimental study showed that smaller nanoparticles are more efficient in their catalytic activity than their larger counter parts. The consistency in sizes and shapes, higher stability and rapid synthesis are the major advantages of this synthesis method. Thus, this procedure of synthesis of gold nanoparticles may offer an attractive alternative to the existing ones and opens a full range of possibilities for various analytical applications.
Dielectronic recombination rate coefficients of fluorine-like nickel
Authors: Wang Shu-Xing , Huang Zhong-Kui , Wen Wei-Qiang , Chen Chong-Yang , Schippers Stefan , Xu Xin , Sardar Shahid , Khan Nadir , Wang Han-Bing , Dou Li-Jun , Mahmood Sultan , Zhao Dong-Mei , Zhu Xiao-Long , Mao Li-Jun , Ma Xiao-Ming , Li Jie , Tang Mei-Tang , Mao Rui-Shi , Yin Da-Yu , Yuan You-Jin , Yang Jian-Cheng , Shi Ying-Long , Dong Chen-Zhong , Ma Xin-Wen , Zhu Lin-Fan
Published: July 2019

Electron-ion recombination rate coefficients for fluorine-like nickel ions have been measured by employing the merged-beam technique at the cooler storage ring CSRm at the Institute of Modern Physics in Lanzhou, China. The measured spectrum covers the energy range of 0–160 eV, including all the dielectronic recombination (DR) resonances associated with ΔN = 0 core excitations. The DR cross sections in this energy range were calculated by a relativistic configuration interaction method using the flexible atomic code (FAC). Radiative recombination (RR) cross sections were obtained from a modified version of the semi-classical Bethe & Salpeter (1957, Quantum Mechanics of One- and Two-Electron 56 Systems (Springer)) formula for hydrogenic ions. The comparison between the measurement and the calculation shows that the present theoretical model still needs to be improved at low collision energies. Temperature dependent plasma recombination rate coefficients were derived from the measured DR rate coefficients in the temperature range of 103–108 K and compared with the presently calculated result as well as previous available data in the literature. The experimentally derived data agree well with the theoretical calculations for temperatures where Ni19+ ions form in collisionally ionized plasmas. At lower temperatures typical for photo-ionized plasmas, discrepancies are found beyond the experimental uncertainty, which can be attributed to the disagreement between the measurement and the calculation of the low-lying DR resonances. The present experimental result benchmarks the plasma DR rate coefficients, in particular for temperatures below 105 K where the ΔN = 0 DR resonances dominate.
Durability and modern technologies of strengthening culverts and animal crossings
Authors: Wysokowski Adam
Published: July 2019

The paper discusses selected issues regarding to repair and reinforcing methods of the of culverts and animal crossing structures. Information was also provided on materials used for construction, and renovation of culverts. In addition, the paper discusses the most commonly used technologies of reinforcing and reconstructing these objects. Particular attention has been paid to the ways of selecting the reinforcement method and systems, taking into account the properties of the materials used in the renovation of these structures. In addition, the paper, according to the author, arranges also issues related to the proper performance of renovation for road culverts.
Causes of failures of industrial floors and concrete surfaces – case study
Authors: Kiernożycki Włodzimierz , Błyszko Jarosław
Published: July 2019

The article presents selected cases of damages to industrial floor and road concrete surfaces. he article presents 3 different objects in which damages were not connected with their excessive service load, but resulted from improper execution, design and underestimation of the effects of forced loads. In each presented case the description of damages was presented, the reasons for their occurrence were analysed and recommendations for repair were given.