bluuebunny/crossref_metadata_2025 huggingface dataset:
Caracterización fenotípica de tres cultivares regionales de arracacha (Arracacia xanthorrhiza Bancroft) en Tolima, Colombia
Authors: Garnica Montaña Johanna Paola , Villamil Carvajal Jorge Enrique , Atencio Solano Liliana Margarita , Jaramillo-Barrios Camilo Ignacio
Published: April 2021

La especie xanthorrhiza del género Arracacia pertenece a la familia Apiaceae y es conocida por su capacidad de generar raíces tuberosas reservantes que se cosechan de forma anual y se comercializan en fresco en países de Sudamérica como Colombia, Brasil, Venezuela, Perú, Bolivia y Ecuador. En Colombia el cultivo de arracacha se realiza principalmente en 15 departamentos y los cultivares regionales se diferencian por el color de las hojas, pecíolo y raíz tuberosa, siendo los más conocidos amarilla común o paliverde, yema de huevo y cartagenera. Existen estudios que han caracterizado los materiales regionales aplicando un limitado número de descriptores, pero no permiten conocer la morfología y diferenciación fenética de cada uno, por lo tanto, su definición y caracterización constituyen un soporte en programas de mejoramiento que permiten el uso eficiente del potencial genético y ampliar el conocimiento sobre la diversidad de cultivares. Se realizó la caracterización y descripción fenotípica de tres cultivares durante dos ciclos de producción (2016 y 2018) en dos fases (vegetativa y productiva) aplicando 74 variables morfológicas (42 cualitativas y 32 cuantitativas) organizadas en siete grupos de variables: planta, hoja, folíolo, pecíolo, propágulo, cepa y raíz tuberosa. Se hizo un análisis factorial para datos mixtos (AFDM) que incorporó un análisis multivariado con la totalidad de variables e identificó 11 variables discriminantes, 8 cualitativas y 3 cuantitativas, las cuales pueden ser empleadas en procesos de caracterización de materiales de arracacha. Se realizó una descripción morfológica de cada cultivar, lo cual significa que este es el primer estudio de caracterización completa de materiales regionales de arracacha en Colombia.
Aceptabilidad por el conejo de la harina de coco desgrasada entre diferentes fuentes de alimento
Authors: Acosta Acosta Yanixi , La O Michel Ángel Luis , Valdivié Navarro Manuel , Betancourt Santos Nelson Nixon , Villalón Moracen Yudelkis
Published: April 2021

Con el propósito de determinar el grado de aceptabilidad de la harina de coco desgrasada suministrada como alimento único e incorporado en diferentes niveles en la dieta para conejos, fueron realizados dos experimentos en los que se emplearon diseños bloques al azar. En el primer experimento los tratamientos fueron: T1 harina de maíz, T2 harina de alfalfa y T3 harina de coco desgrasada; para el segundo, los tratamientos consistieron en el suministro de las dietas con la inclusión de 0, 10, 20, 30 y 40 % de harina de coco desgrasada.  En los dos estudios se utilizaron conejos machos de la raza chinchilla de 80 días de edad, con un peso promedio de 2150 ±103 g, 21 y 35 animales respectivamente. Se observó una conducta similar en las variables intento de consumo y consumo de alimentos, tanto cuando se suministró la harina de coco desgrasada como alimento único como cuando se mezcló con otros ingredientes. Los animales realizaron intentos de consumo durante casi las 24 h, con los mayores intentos de consumo en el horario nocturno. Los animales muestran la mayor aceptación por las dietas del 10 % de inclusión de harina de coco desgrasada. Los resultados sugieren que la harina de coco desgrasada es un subproducto agroindustrial con potencialidades para ser incorporada en las dietas de conejos y sustituir alimentos convencionales tradicionalmente empleados en los piensos elaborados para esta especie.
Perspectiva de la Ingeniería Geográfica y Ambiental a partir de la producción académica potenciada desde el pregrado
Authors: Olarte Riaño José Ricardo , García Espitia Daniel Fernando , Posada Arrubla Adriana
Published: April 2021

Producir nuevo conocimiento en disciplinas emergentes que combinan varios campos del saber es aún una tarea que tiene un largo camino por recorrer, particularmente sobre integraciones entre temas ambientales y geográficos en los cuales algunos investigadores de amplia trayectoria han generado aportes importantes. En este artículo se revisan los pasos de jóvenes que, desde una ingeniería de contexto latinoamericano, empiezan a expresar al mundo sus ideas. El objetivo es establecer una perspectiva de la Ingeniería Geográfica y Ambiental a partir de la producción académica que es potenciada desde el pregrado. La metodología se desarrolló en cuatro etapas que iniciaron con la exploración y compilación de 91 productos académicos visibles en el periodo 2005-2019, lo que permitió una categorización posterior; luego se pasó a un análisis cuantitativo general de los contenidos y se complementó la perspectiva con la aplicación de una entrevista sintética a expertos. Como resultados, se logró clasificar la producción académica en cinco categorías y trece subcategorías, se realizó un análisis espacial de tal producción y se evidenció un proceso constructivo de aportes sucesivos. Con ello, se muestra una exploración que permite trazar nuevas trayectorias, revisar la posibilidad de vincular esfuerzos y, sobre todo, impulsar a las nuevas generaciones en el ejercicio del diálogo de saberes y la interdisciplina.
Marcos Saquet. Saber popular, práxis territorial e contra-hegemonia
Authors: Flávio Luiz Carlos
Published: April 2021

Saquet, M. (2019). Saber popular, práxis territorial e contra-hegemonia. Editora Consequência, 141 pp. ISBN: 9788569437628.

Saquet, M. (2020). Saber popular, praxis territorial e contra-hegemonía. Editorial Itaca, 128 pp. ISBN: 9786078651382.

O livro é uma leitura primorosa para se pensar a relação da universidade com a sociedade e os movimentos sociais do/no campo/cidade! A principal contribuição é tentar aliar as pesquisas com ações de projetos de extensão realizados, demonstrando um pensamento profundo que se propõe à reflexão acadêmica que busca implementar ações sociais.
Community environmental education and the struggle for water
Authors: Pelacani Bárbara , Kassiadou Anne , Camargo Daniel Renaud , Sánchez Celso , Stortti Marcelo
Published: April 2021

In this article, we propose to reflect on the environmental education that emerges from the conflict over the construction project of the Guapiaçu dam, in Cachoeiras de Macacu, Rio de Janeiro. To this end, we start from the perspective of community environmental education developed by the Environmental Education Study Group from the South, especially in the interaction with the Movement of Dam Affected People, for the pursuit of environmental justice. Thus, such meetings unveil the necropolitical bias of this “development” project, that clashes with farmers and with life in this territory. Therefore, we highlight the communityenvironmental education, interwoven from the encounter with the voices and the waters that flow through this environment, as a possible way to confront a necropedagogy that supports such necropolitics.
La educación como espacio en disputa entre el campesinado y el agronegocio
Authors: Urdampilleta Constanza María , Totino Mariana , Ithuralde Raúl Esteban
Published: April 2021

En este texto presentamos un trabajo de indagación sobre las formas en que el conflicto ambiental entre el campesinado y el modelo del agronegocio en Santiago del Estero, Argentina, se expresa en el campo educativo. Para llevar adelante este estudio de corte cualitativo, realizamos primero entrevistas semiestructuradas y observaciones participantes en reuniones y talleres en comunidades campesinas de las sierras de Guasayán. Luego revisamos documentos de organizaciones campesinas de la provincia de Santiago del Estero. Después se realizaron ciclos sucesivos de codificación abierta y axial. Los resultados se estructuraron en los siguientes ejes conceptuales: (1) sistema escolar en los territorios campesinos, (2) aprendizaje por participación en las comunidades y en el movimiento y (3) Escuela de Agroecología. La conclusión es que el campo educativo es uno de los contextos de disputa entre el campesinado y el agronegocio en la lucha del primero por su propia (re)existencia. Resaltamos así la importancia de mirar no solo cómo se representan los conflictos ambientales en el sistema educativo, sino también las prácticas de agentes educativos en dichos conflictos.
El ajuste situado hacia una obra audiovisual: el afinamiento de la sensibilidad mediada culturalmente
Authors: Santana Espitia Ana Cristina , Fajardo Santamaría Jesús Armando
Published: April 2021

El marco de intencionalidad hábil [SIF] es una perspectiva que permite estudiar la cognición en prácticas socioculturales. Se trata de una aproximación ecológica que puede adaptarse para comprender las situaciones de enseñanza-aprendizaje. Este estudio tiene como objetivo lograr una aproximación al SIF del espectador académicamente involucrado con una obra de cine. Se realizó una experiencia etnográfica virtual, en la que se exploraron textos escritos por dos grupos de estudiantes de psicología académicamente involucrados con temas de estudio diferentes, a partir de la visualización de una obra de cine. Para el análisis cualitativo, se describieron los términos más frecuentes hallados en las producciones escritas de los estudiantes y se examinó la proximidad entre estos términos a través de análisis de conglomerados. Se propone una interpretación de las tendencias halladas, según la cual la sensibilidad de los participantes se ajusta a la observación de la obra de cine orientada por la configuración específica de las solicitaciones de cada práctica educativa. Las ideas de este estudio son relevantes para diseñar experiencias significativas de construcción de conocimiento en el aula.
Framework for the Comparison and Selection of Schemes for Multi-Factor Authentication
Authors: Velásquez Ignacio
Published: April 2021

Authentication is the process of verifying a user’s identity for them to access a system’s resources. An authentication factor is a piece of information used for this authentication. Three well-known groups of authentication factors exist: knowledge-based (what you know), possession-based (what you have) and inherence-based (what you are). Authentication schemes belonging to distinct authentication factors can be combined in a multi-factor manner to increase security. Although multiple multi-factor proposals are seen in literature, the absence of a method that allows a proper comparison and selection of these authentication methods, based on an application’s security requirements, can be observed. Existing frameworks for the analysis of authentication methods have been identified through the realization of a systematic literature review, but most of these focus on specific contexts and do not provide a generic enough solution. Due to the above, this research focuses on the creation of a recommendation framework that guides in the comparison and selection of single and multi-factor authentication schemes, considering both the application’s requirements and its context. This has been attained not only through the knowledge found in literature, but the experience from industry experts has been compiled as well through the collaboration with a multinational software development company. Consequently, the knowledge found in literature has been obtained from a systematic literature review, whereas the experience from industry experts was obtained through a survey and interviews. The framework proposal has been generated based on the above and has been validated through an expert panel and a case study methodology in collaboration with the partnered software development company. A tool prototype has been constructed as well. The result is a recommendation framework for the comparison and selection of authentication methods that can support this decision process in multiple contexts.
Endoscopic findings in the older patients with iron-deficiency anemia
Authors: ŞENKAYA Ali , ÇELİK Ferit , ÖZÜTEMİZ Ömer
Published: April 2021

Aim: The presence of iron-deficiency anemia, which is an important indication for endoscopic

procedures, in the geriatric population necessitates the exclusion of a possible malignancy in the

gastrointestinal system. This study aims to examine endoscopic findings in geriatric patients that

underwent esophagogastroduodenoscopy and colonoscopy because of iron-deficiency anemia.

Materials and Methods: Sixty patients aged 65 and over who underwent

esophagogastroduodenoscopy and colonoscopy because of iron-deficiency anemia between August

2019 and August 2020 were retrospectively evaluated. Age, sex, geriatric age groups of patients,

presence of Helicobacter pylori in gastric biopsy, esophagogastroduodenoscopy findings, colonoscopy

findings, presence of internal and / or external hemorrhoids, and duodenal biopsy results were

examined.

Results: Thirty (50%) of 60 patients included in the study were male and the mean age was 72.47 ±

6.07 years. Of these patients, 41 (68.4%) were young-old, 17 (28.3%) were middle-old and 2 (3.3%)

were old-old. The most common causes that might explain iron-deficiency anemia in

esophagogastroduodenoscopy were atrophic gastritis (21.2%), Helicobacter pylori-positive gastritis

(20%), gastric polyp (11.7%), and gastric cancer (3.3%), whereas colonoscopy results were found

colon polyps in 23.3% of patients, diverticulum in 15% and angiodysplasia in 15%, and colon cancer in

8.3%. Internal hemorrhoids were also observed in 44 (73.3%) patients.

Conclusion: In the older population, blood loss from the gastrointestinal system is the most important

cause of iron-deficiency anemia and just hemorrhoids cannot explain IDA. While examining the

etiology of patients diagnosed with iron-deficiency anemia, performing both

esophagogastroduodenoscopy and colonoscopy is an accurate approach to reach the underlying

cause and not to miss a possible malignancy
Burden, quality of life and coping strategies of palliative care patients’ caregivers
Authors: TİMUR Özge , GÜNDÜZ Nermin , ALTAŞ Halime , TURAN Hatice , KARAŞAHİN Ömer , TOSUN TASAR Pınar , BİNİCİ Doğan Nasır
Published: April 2021

Aim: The burden of the caregiver can affect the caregiver socially, psychologically and physically in time. Since becoming a caregiver is always an unpredictable situation adaptation to this situation takes place after the situation arises. The aim of this study is to examine the attitudes of coping with caregiver burden and quality of life in caregivers of patients hospitalized in palliative care units.

Materials and Methods: The study was carried out with caregivers of 59 hospitalized patients in the palliative care unit of a university hospital. The Zarit caregiver burden scale was used to determine the caregiver burden, the SF 36 to determine the quality of life, and the COPE self-report scales to reveal the coping attitudes.

Results: The mean score of Zarit caregiver burden scale in caregivers was 50.7 and was interpreted as a moderate burden. The highest score among the COPE subscale scores was COPE 7 (religious coping) (15.7); the lowest score is COPE 12 (4.4) (Substance use). A significant negative correlation is found between the Zarit caregiver burden scale and the education level of the caregiver (R = -0.291, p = 0.025).

Conclusion: Caregiver burden is the totality of possible physical, psychological, social or financial responses while providing care. In our country, mostly women, unemployed and low-educated family members become caregiving. In our study, the participants defined a moderate burden, although they provided care to chronic and severe patients. This indicates that in addition to the treatment of patients in palliative care centers, caregivers are also provided with medical, social and psychological support.
Huzurevlerinde yaşayan yaşlı bireylerde fiziksel aktivitenin uyku kalitesi üzerine etkisi
Authors: DAŞDEMİR İLKHAN Gülay , ÇELİKHİSAR Hakan , KILAVUZ Aslı
Published: April 2021

Amaç: Bu çalışmanın amacı, huzurevinde yaşayan 65 yaş ve üzeri yaşlı bireylerin fiziksel aktivite ile uyku kaliteleri arasındaki ilişkiyi değerlendirmektir.

Gereç ve Yöntem: Çalışmaya huzurevlerinde yaşayan toplam 456 yaşlı birey dahil edildi. Karşılıklı görüşme yöntemiyle demografik bilgileri kaydedildi. Yaşlıların gündüz uykululuğu (Epworth Uykululuk Skalası), fiziksel aktivite düzeyi (International Physical Activity Questionnaire) ve uyku kalitesi (Pittsburgh Uyku Kalitesi İndeksi) değerlendirildi.

Bulgular: Bireyler fiziksel aktivite düzeyine göre puanlanarak gruplandırıldı. Uyku kalitesi açısından gruplar arasında anlamlı fark görülmemiştir (p = 0,41). Gündüz uykululuğu açısından ise gruplar arasında istatistiksel olarak anlamlı fark saptanmıştır (p
Association of muscle strength and muscle mass with body mass index and insulin treatment in older patients with type 2 diabetes mellitus admitted to geriatric outpatient clinic
Authors: KAYHAN KOÇAK Fatma Özge , SAVAŞ Sumru , AKÇİÇEK Selahattin Fehmi
Published: April 2021

Aim: The aim of this study was to investigate the hand grip strength and muscle mass of older patients with type 2 diabetes mellitus in relation to body mass index and insulin treatment.

Materials and Methods: A total of 123 older patients with diabetes mellitus ≥65 years of age were admitted to geriatric outpatient clinic of a university hospital between October 2015 and October 2019. Demographic data, medical records, laboratory results, hand grip strength and muscle mass were derived from the hospital records, retrospectively.

Results: The patients were grouped according to body mass index and usage of insulin treatment. There was a negative correlation between body mass index and hand grip strength (p = 0,002), and a positive correlation between body mass index and muscle mass index (p = 0,001). No significant differences for hand grip strength and muscle mass index were observed between insulin treatment group and non-insulin treatment group.

Conclusion: In type 2 diabetes mellitus patients with normal weight and obesity, anthropometric differences should be considered to identify true sarcopenic patients. Assessment of muscle strength, and also evaluation of muscle quality might be more valuable than assessment of muscle mass for those patients
Potentially inappropriate medication usage, fall and comorbidities in geriatric patients diagnosed with chronic subdural hematoma
Authors: TAŞKIRAN Emin , GÜRKAN Gökhan , SEVİN İsmail Ertan , SARAÇ Zeliha Fulden
Published: April 2021

Aim: The annual incidence of chronic subdural hematoma is 2-4/100000 in geriatric population. We aimed to investigate relationship between potentially inappropriate medication usage according to Beers 2019 criteria, fall and Charlson comorbidity index in geriatric patients diagnosed with chronic subdural hematoma.

Materials and Methods: We retrospectively collected medical records of 69 geriatric patients diagnosed with chronic subdural hematoma and hospitalized for the last 5 years in neurosurgery department of Izmir Katip Çelebi University Hospital with the permission of local ethical committee of medical faculty. Data was recorded and analyzed with appropriate method by using SPSS v18.

Results: Mean age was 78.43 ± 7.51 years, mean Charlson comorbidity index was 5.87 ± 2.97. Falling events were responsible for 59 (85.5%) out of 69 chronic subdural hematoma cases. Potentially inappropriate medication usage according to Beers 2019 criteria was found in 20 (29%) patients. Inappropriate medications belonged to cardiovascular system (14.5%) class and antiplatelet/anticoagulant (14.5%) class mostly. When group was divided into two groups as patients who used potentially inappropriate medication or not, Charlson comorbidity index was found to be higher in the first group. (p 0.05). Charlson comorbidity index and number of medications showed significant correlation (p = 0.001).

Conclusion: We could not reach a significant correlation between fall, Charlson comorbidity index and potentially inappropriate medication usage in our retrospective study. Small study population size, unreliable medical records and relatively healthy characteristics of population may contribute to crossing results.
The relation between joint physical custody, interparental conflict, and children's mental health
Authors: Augustijn Lara
Published: April 2021

Objective: This study investigated the relationship between joint physical custody and children’s mental health, and tested whether interparental conflict moderated the association.

Background: Joint physical custody is an emerging post-separation care arrangement that is expected to counter the negative effects of family dissolution on children’s overall well-being. There is, however, substantial disagreement about the impact that joint physical custody may have on children’s mental health when interparental conflict is high.

Method: The statistical analysis was based on data from the Family Models in Germany (FAMOD) study, which was conducted in 2019. The analytical sample consisted of 1,087 post-separation families practicing either sole physical custody or joint physical custody. Linear regression models were estimated to determine the relationship between physical custody arrangements, interparental conflict, and children’s mental health problems.

Results: Living in a joint physical custody arrangement was positively related to children's mental health, whereas high levels of interparental conflict were negatively related to children's mental health. However, when levels of interparental conflict were high children in joint physical custody arrangements displayed levels of mental health problems that were quite similar to those of children in sole physical custody arrangements.

Conclusion: The findings emphasize that joint physical custody is not a "one-size-fits-all model" that is suitable for all post-separation families, and that it is only beneficial for children's mental health when interparental conflict is low.
A new method of closing the defects of chest wall
Authors: Dambaev G. Z. , Gunter V. E. , Philippov S. G. , Sokolovich E. G. , Topolnitsky E. B. , Doroshenko A. V.
Published: April 2021

There was worked out a new method of plastics of chest wall defects by means of construction from nikelide of titan. An experimental examination of effectiveness of the method with the use of clinical, roentgenological and morphologic control was carried out. The method provides normalization of biomechanics of respiration by means of restoration of osteochondrous skeleton and liquidation of cosmetic defection.
The usage of modern radial diagnostic technologies in practical medicine
Authors: Zavadovskaya V. D.
Published: April 2021

In the article the view of the scientific researches of the Department of radial diagnostic in SSMU is presented. Within the frames of the department interests besides the traditional researches in the fields of roentgenology there are such modern methods of medical visualization as search of new methods of osteoporosis-very developed and socially significant disease. The possibilities of usage the ultrasound for revealing the acute surgeon pathology of stomach and also for determination of criterias of activity of rheumatoid arthritis in knee-joint are studied. The new radioisotope methods of visualization of inflammatory processes of different localization are worked out. The possibilities of HRCT in the diagnostic of chronical obstructive diseases of lungs and obstructive bronchitis (COB) and bronchial asthma (BA) are researched. The intrusion of radial diagnostic methods for the determination of toxic influence of hepatite and drugs on the condition of parenchymatous organs existing in people who are drug addicts appears to be a new direction in work of the Department.
Typical reaction of peripheral link of erythron in the pathological processes
Authors: Ryazantseva N. V. , Stepovaya E. A. , Kolosova M. V. , Novitsky V. V.
Published: April 2021

A complex research of the structural-metabolic features and the functional status of erythrocytes in peripheric blood of people with mental disorder and somatic pathology was carried out. It was revealed that when having schizophrenia, exogenous mental deficiency, neurotic disorder, Alzheimer's disease, malignant neoplasm of different localization, chronicle nonspecific diseases, acute pneumonia, atherosclerotic affection of limbs’ arteries, heat injury there are evident abnormalities of albuminous and lipid composition of membrane of erythrocytes, change of microviscosic features of lipid phase and disorder of cationtransporting membrane system, disorganization of superficial architectonics and ultrastructure of red blood cells, their deformation and aggregative features. The discovery of nonspecific character of structural-functional disorders of erythrocytes in the pathological processes and conditions allows to suggest that there is typical reaction of peripheric link of erythrone.
The influence of functional skewness on prognosis of cancer of mammary gland
Authors: Erendeeva L. E. , Zavyalova M. V. , Slonimskaya E. M. , Perelmuter V. M.
Published: April 2021

In this study the features of developing cancer both in the left and right breast have been compared. We examined 45 parameters which characterize clinical as dell as morphological features of breast cancer. Of all parameters investigated only 5 are more informative ones. They show that breast cancer is developing differently in the right and the left breast. We conclude that localization of cancer in the right breast has a worse prognosis. The results obtained are discussed.
The patent services of the institutions of higher education — one of the key elements in formation and realization of the government politics of Russian economical rise
Authors: Zubareva N. G.
Published: April 2021

The process of formation of a single government politics in the sphere of industrial property is discussed. It is pointed out that economical significance of the objects of IP is rising because of priority orientation of the Russian science and industry on making scientific, good production. The questions of effective legal protection and commerce realization of the IP objects are also touched. It is settled that support and development of the patent service in the institutions of higher education are necessary.
The influence of urogenital infections on pregnancy, condition of foetus and neonate
Authors: Gabidulina T. V. , Timoshina E. L. , Yuryev S. Yu. , Makhmuthodzhayev A. Sh.
Published: April 2021

It is proved that intrauterine infections influence negatively on the period of pregnancy, the condition of fetus and newborn on the example of isolated, chlamydeous and chlamydeous-virus infections. The schemes of treatment of pregnant women in these groups are determined. It is revealed that the percentage of the possibility and the degree of heaviness of intrauterine infection is lowing if the newborn were born by women who got the treatment in the period of pregnancy.
To the question about the history of municipal public health services (on the example of the provincial town Tomsk)
Authors: Adamyan A. T.
Published: April 2021

On the base of archive documents the comparative characteristics of the situation in health service in Tomsk of the beginning of XX century and of modern situation in health service in Tomsk is given.
Histology and Embryology Department of Siberian State Medical University. Tomsk period of Dogel’s activity (to 150 universary from the birthday)
Authors: Logvinov S. V. , Ryzhov A. I. , Malinovskaya I. S. , Nekrylov S. A.
Published: April 2021

Alexander S. Dogel (1852—1922) is salient Russian scientist, one of Neurohistology’s founders, the first manager of Histology’s department of Tomsk University (1888—1895), professor of medicine, Associate Member of Russian Sciences Academy, the founder of «Russian Archive of Anatomy, Histology and Embryology» journal, member of Committee of Nobel’s premium’s award. His scientific works in region of Neurohistology and sense’s organs are fundamental. Some kinds of retina neurons and vegetal ganglions are named after Dogel in the whole world.
The rolle of carbohydrate component of neutrophil membrane glycoprotein receptors for change of its functional activity at patients with acute coronari syndroms and its combination with diabetes mellitus type 2
Authors: Kiritchuk V. F. , Koscheleva N. A. , Rebrov A. P.
Published: April 2021

The aim of this work is to gind ont influence of сarbohydrate сomponent of membrane glycoprotein receptors on the change of its functional activity at patients with acute coronari syndromes and its combination with diabetes mellitus type 2. 69 sich men and 20 nearly healthy men were examined. Among the patients 32 men sugger from acute coronari syndromes, 17 men — from combination with diabetes mellitus type 2 and 20 men — from diabetes mellitus type 2 only. Neutrophil aggregation induced by method by Gabbasov and another autors (1989). Wheat Germ Agglutinin (WGA), Concanavalin A (Con A), Phitogemagglutinin (PHA). At patients with acute coronari syndromes aggregation of neutrophile isincreaced under affect of N-acetyl-D-glucosamin and acidi syalici and at patients with diabetes mellitus type 2 — under affect of mannose and bD-galactose. In the case of the combination of acute coronari syndromes and diabetes mellitus type 2 the rise of aggregation is connected not only with increase of mannose and bD-galactose but also with increase of N-acetyl-D-glucosamin and acidi syalici. Neutrophile' carbohydrate structure is restored under affect of defenite therapy.
Research biologically active substances Atragene speciose Weinm.
Authors: Shilova I. V.
Published: April 2021

From the overground part of Atragene speciosa Weinm. family Ranunculaceae, we obtained a fraction possessing a marked nootropic effect from which 3,4-dihydroxyphenylethanol-2, its 2-O-β-D-glucopyranoside, and a sum of glycosides of dihydroxybutane acid were isolated. In addition to the foregoing substances, in the pharmacologically active fraction we revealed the presence of triterpene glycosides (whose sapogenins are hederagenine and oleanolic acid), aminoacids and microelements. For the frist time the obtained data about the biologically active substances and their pharmacological activity give us the possibility of development of a new phytopreparation with the nootropic effect on the basis of Atragene speciose Weinm.
The mechanisms of blood system regulation under myelosuppressive influences
Authors: Goldberg E. D. , Dygai A. M. , Zhdanov V. V.
Published: April 2021

As a result of many years experiments by studying of blood system function under radiation and cytostatic myelosuppressions it has been shown, that observing changes and mechanisms, underlying in their basis, are unspecific and of the same type. However the specific reaction of blood system depends on the nature of acting irritant. The hemopoiesis recovery dynamics, together with direct suppressed effect of toxic agents on hemopoietic cells, in many respects, is determined by character of regulatory systems, and first of all separate elements, forming hemopoiesis – inducing microenvironment.
Programmed hypocoagulation in combination with reinfusion of one’s own cell-like mass in complex treatment of children’s appendicular peritonits
Authors: Solnyshco A. L. , Shalygin V. A. , Boldyshev D. A. , Bocharov R. V.
Published: April 2021

Patients with an appendicular peritonitis were studied with the disfunctions of a hemostasis and modular conditions of a blood. The experiments were carryed-out with the help of an analyzer of the reological properties ARP-01 «Mednord». 22 children had been examined. The scheme of the developing hypocoagualation was developed. The positive effect of combination of controlled gipocoagulation and antibiotic therapy is marked with the help of cell-like mass inkubation method.
Generally physiological and evolutionary conceptions of natural science in scientific heritage of academician N.V. Vasilyev
Authors: Kolyada T. I.
Published: April 2021

The main stages of scientific activities and main published works in scientific heritage of outstanding scientist N.V. Vasilyev., academician of the Russian Academy of Medical Sciences and academician of the Ukrainian of Ecological Sciences have been presented.
Radiofrequency transmyocardial revascularization in experiment
Authors: Opherkin A. I. , Logvinov S. V. , Pokushalov Y. A.
Published: April 2021

Conducted benchmark analysis of influence to mechanical punctures, transmyocardial radiofrequency influence and lazer radiating on myocardium. Study is conducted on 284 rats. Transmyocardial revascularization (ТМR) was executed with use intramuscular needle, Nd:YAG lazer, radiofrequency generator with needle electrode. Study of vascular density and myocardial perfusion was conducted through 1, 2, 4 and 8 weeks. Maximum increasing vascular density was observed on 4 week. In groups with radiofrequency TMR and Nd:YAG TMR specific vascular volume is enlarged in 5 once (26,9 ± 1,9% and 22,2 ± 1,7%, accordingly; Р < 0,05) in contrast with the checking group (4,9 ± 1,6%). In the group with mechanical ТМР specific vascular volume is enlarged small (6,1 ± 1,3%). Increasing an accumulation 99mTc-myoview in the group with radiofrequency TMR occurred on 8 week by comparing with the checking group, it has formed 2,82 ± 0,31% (Р < 0,05) and 1,68 ± 0,21% accordingly. Conclusion: Analysis of vascular density points to alike efficiency of lazer and radiofrequency transmyocardial revascularization. Radiofrequency ТМR causes an increasing vascular density and improvement myocardial perfusion in ischemic myocardium.
Condition of lipid metabolism at women of genesial period and its correlation with functional activity of thyroid gland and ovary
Authors: Korchin V. I. , Korneeva E. V.
Published: April 2021

In the present work all possible correlations between functional status of thyroid gland, ovaries and lipids of Serum of blood at women of genesial period living in Far North for a long time are investigated. In the process of investigation there was indentified that women with cyst of ovary have a rise of general cholesterol and cholesterol of lypoproteid of low solidity.
Ethic committee of Siberian State Medical University
Authors: Kondratyeva E. I. , Saratikov A. S.
Published: April 2021

In the article the international principals of creation and activity of ethic committees are editorialized. Also there are documents on which ethic evaluation of scientific researches is based. These documents underlay the regulation about ethic committees that was created in Siberian State Medical University. The organization structure of the ethic committee in SSMU is presented.
Evidence based medicine for professional training of physicians: informational and economical aspects
Authors: Fokin V. A. , Karas S. I. , Kalitvyanskaya T. A.
Published: April 2021

Possible approaches to teaching of methodology of evidencebased medicine in medical university and post degree education of specialists are discussed. There are examined the informational and economical factors leading to raising of medical decisions and introduction of demonstrative approach to medical pr.
Two-step sclero-corneal tunnel incision for cataract surgery
Authors: Neyasov V. S. , Ekimov A. S.
Published: April 2021

The modification of small tunnel sclero-corneal incision for lens extraction is suggested. The influence of the incision on corneal curvature and its ability to provide intraoperative and postoperative eyeball hermeticity is experimentally studied.
110th jubilee of psychiatry, narcology, psychotherapy and medical psychology Department of SSMU
Authors: Balashov P. P.
Published: April 2021

In the article there are introduced the history of Department, the names of its grounders, the key events of scientific life of the department, the prospects of its development.
Coordinational council of the young scientists in Siberian State Medical University
Authors: Kapilevich L. V.
Published: April 2021

The principals of creation and activity of Coordinational council of the young scientists in Siberian State Medical University are presented. The organizational structure and the main activities of Coordinational council of the young scientists in SSMU are shown.
Logical and gnoseological features of diagnosis
Authors: Sukhotin A. K.
Published: April 2021

A diagnosis, as a type of getting knowledge (alongside with science and education) goes from consequences to a reason (from symptoms to nosological unit), this determines it’s hypothetical character. There is a choice amongst variants, exposed by method of differential diagnosis, which is been realized on the ground of logical operations of moving out hypothesises and constructing analogies. Though a diagnosis don’t carries a new knowledge, it presents a creative process, which is been understood as carring out the essential human sorces in their full realization (the basic creative law).
Physician’s knowledges and cogitations during making of clinical diagnosis
Authors: Tetenev F. F. , Bodrova T. N.
Published: April 2021

The Authors do the attempt to understand and explain, what image a physician in complex clinical situation puts the diagnosis of disease, which it does not know. Such possible if physician speculates on clinical picture. It is offerred differentiate the notions «knowledges» and «cogitations of physician».

The cogitations of physician exceed the volume of concrete its knowledges (including reference literature) due to presentation and imagination, which allow to build the diagnostic hypothesises and goal-directed to lead searching for new  for itself knowledges in process of checking the hypothesises. The development of ability to speculate on clinical picture provide the knowledges:

1. General and private semiology.

2. Characteristics an symptoms, syndromes, diagnosis.

3. The main laws of logic, философии and the general pathology.

Allegorizes and is motivated the judgement that study of theory of diagnostics promotes the development of ability to speculate the clinical thinking on clinical picture and active shaping.
Тreatment of the chronic opisthorchious pancreatitis
Authors: Alperovich B. I. , Kurysko Zh. A.
Published: April 2021

192 consecutive patients with chronic pancreatitis against the background of chronic opisthorchious invasion were observed from 1970 to 2000 years in the Tomsk region hepatological center (female — 117 (60,9%), male — 75 (39,1%)). 166 (86,5%) patients were treated therapeutically (anti-fermentative, analgesic, anti-spasmodic drugs drugs, and substitution fermentative therapy). 26 of them (13,5%) were incapable of improvement. Preoperative diagnostic is based on detection specific peculiarities of chronic opisthorchiоs pancreatitis on the background of opisthorchiоs invasion. Original classification of the chronic opistorchious pancreatitis was suggested. Specific developed surgical tactic allows distinguishing the best radicalism of operations, to warn appearance of specific complications.
Using of oxygenic infusion solutions in treatment of patients with bronchial asthma
Authors: Belousov E. V. , Dambaev G. Ts. , Avramchik O. A. , Korotkova E. I. , Belousova N. I. , Kutsenko A. E.
Published: April 2021

Oxygen concentration before and after oxygenation and relaxation time were determined by the method of cathodic voltammetry in infusion solutions, such as physiologic solution — 0.9% NaCl, Ringer-Locc’s solution, glucose — 10%, poliglucin, haemodes, oxigenated by 5 athm. pressure.

There were given the recommendations for practical usage of oxigenated infusical solutions.The most optimal solutions for the oxygenotherapy are physiologic solution and poliglucin. 12 patients with bronchial asthma were treated with these solutions successfully.
The results of microbiological methods of investigation of tuberculosis in Altay region
Authors: Strelis A. K. , Lukyanenko N. V. , Sultanov L. V.
Published: April 2021

The qualitative and quantitative aspects of microbiological diagnosis of tuberculosis from 1996 to 2001 in Altay region are presented. In the process of realization of regional complex program «Fighting with tuberculosis» the positive dynamics of microscopy. The improvement of material technical basis of laboratory service, modern equipment, staff training helped in this process.
The history of forensic medicine department SSMU (to the 110th jubilee)
Authors: Shamarin Yu. A. , Melchikov A. S. , Shnayder A. D.
Published: April 2021

In the article there are introduced the history of forensic medicinе department, the names of its grounders, the key events of the scientific life of the department, the prospects of its development are introduced.
Foundation history of the first bacteriological institute in Siberia (on the occasion of centenary of the foundation of Ivan and Zinaida Churiny Bacteriological Institute)
Authors: Kharitonova E. M. , Tolopilo A. G.
Published: April 2021

In this article there is presented the information about the first Siberian Bacteriological Institute, it history, role and traditions. Names and biographies of the creators of this medical institution are given.
Traditions of classic domestic medicine in the works of Tomsk medical scientists and philosophers
Authors: Garganeyeva N. P.
Published: April 2021

In the article there were discussed clinical and philosophical problems of general diagnostics theory — a fundamental discipline in clinical sciences study and doctor’s thinking. As a basic knowledge there were discussed the works of the biggest domestic physicians and philosophers whose world outlook positions have been united by dialectic problem of medicine study and, despite the test of time, have kept their actuality. Investigations of Tomsk scientists, the leading specialists in methodology and strategy of clinical diagnosis ascertainment, were underlined.
The art of healing pain and suffering
Authors: Chazov Ye. I.
Published: April 2021

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Conclusions by analogy and their place in diagnostics
Authors: Doon E. M.
Published: April 2021

In the article the main point of conclusions by analogy as a kind of logical reasoning and their cognitive value are analyzed. The place of these conclusions in doctor’s thinking is examined. And a criticism of wrong evaluation of conclusions in the diagnosis theory is given.
Controlled laparostomy application method in cases of total peritonitis
Authors: Alperovich B. I. , Barabash V. I.
Published: April 2021

The problem of peritonitis remains actual for practical medicine as the lethality and complications in this pathology are on a high level. General purulent peritonitis is the most dangerous one. This article covers the results of treatment of 52 patients with total peritonitis using our method. It causes the decrease of lethality up to 25%.
Variants of Epstein—Barr viral infection course in infectious mononucleosis nidus for the children
Authors: Pomogaeva A. P. , Galaktionova O. I.
Published: April 2021

The aim of this investigation is to assess variants of Epstein—Barr viral infection course in infectious mononucleosis nidus. There have been examined 5 groups of preschool institutions, in each there was found 1 case of typical infectious mononucleosis caused by Epstein—Barr virus. Total number of children under observation was 67: 5 children with typical (clinical) infectious mononucleosis and 62 children being in contact under the disease. Analyses of life history, clinical examination, peripheral blood examination, serologic marker spectrum of EBV- and HIV-infections and factors of immune system cellular component have been made during investigation. It was found that 1 child in a contact group was absolutely healthy, 53 children were virus carriers and 8 children had atypical infectious mononucleosis. Upon the investigation results the formation of infectious mononucleosis nidus has been proved and their peculiarities have been found.
Microcirculatory injuries of patients with chronic generalized periodontitis and their correction with EHF-therapy
Authors: Kiritchuk V. F. , Lepilin A. V. , Apalkov I. P. , Yerokina N. L.
Published: April 2021

The aim is the study of EHF-therapy (extremely high frequency therapy) potential for the correction of microcirculatory injuries of patients with chronic generalized periodontitis in postsurgery period: in blood rheological properties and hemostasis system, change of oral fluid ability to coagulation. 42 patients have been examined and treated, including a complex periodontium examination: parodontal recess depth, stomatorrhagia at probing and gum capillary resistance. There have been determined a blood viscosity, erythrocyte aggregation, erythrocyte membrane deformability with rotation viscometer ABR-2; as well as activated partial thromboplastin time, prothrombin time, activity with coagulometer «Sola-Cey 2120» (Byelorussia) using reagents of «Tyekhnologiya-standart» company (Barnaul, Russia). An apparatus «Yavj-1» with wave-length of 5,6 mm with the exposure to biologically active face points (cv-26, cv-27, st-7, st-8) has been used for EHF-therapy. There has been demonstrated that patients with chronic generalized periodontitis had blood rheological and coagulation properties disturbed, that accompanied with the increase of blood viscosity, erythrocyte aggregation, tissue prothrombinase activity and the decrease of blood antithrombin and anticoagulant activity. Patients oral fluid components intensify the disturbances in blood rheological properties due to erythrocyte aggregation increase, and at the same time increase the blood coagulation potential. EHF-therapy recovers the blood rheological properties (its viscosity) more effectively, erythrocyte ability to aggregation and hemostasis system factors in comparison with the traditional treatment.
Determination of body surface and direction of crossing with motor transport wheels in forensic medical experience
Authors: Shamarin Yu. A. , Kalyanov Ye. V. , Shnayder A. D.
Published: April 2021

In the article it have been systematized morphologic features allowing to define what body surface had been subjected to the crossing with motor transport wheels and the direction of crossing. Answer to this question is of great practical importance. 60 cases of determined automobile injuries (crossing a body) have been analyzed.
Nikolay Vasilyevich Vershinin: main milestones in scientific-educational and military biography
Authors: Plotnikov Ye. V. , Ronzhin S. G.
Published: April 2021

Here are presented the main milestones in scientific, teaching and military biography of an outstanding Tomsk pharmacologist, member of the USSR Academy of Medical Sciences and a founder of Siberian pharmacologist school — Nikolay Vasilyevich Vershinin.
Metabolic and functional cardiac changes at II-type pancreatic diabetes and abdominal adiposity in rats
Authors: Kolbina M. V. , Dolgikh V. T. , Chesnokov V. I.
Published: April 2021

Investigation of pathogenetic correlation of abdominal adisposity and II-type pancreatic diabetes (PD) has been made with the aim to reveal the importance of carbohydrate metabolism disturbances at above said pathology combination in cardiac abnormalities. 30 white alley rats at the age of 8-12 months have been included into the experimental group. Control group has been formed of 30 animals. Used methods of investigation: simulation of II-type PD in rats with streptozotocin and study of carbohydrate metabolism indices in entire organism as well as contractile function indices and indices of isolated and contracting heart metabolism. As a result it has been revealed that the weight of rats with II-type PD and abdominal adisposity, the level of glucose and glycated haemoglobin in blood, of lactate and pyruvate had been increased surely. The normal level of blood serum C-peptide has confirmed the absence of mass death of β-cells. The hearts taken from diabetic animals have responded to the increase of contraction frequency with the decrease of advanced pressure, i.e. the negative inotropic effect has been observed. Therefore the peripheral insulin resistance plays the leading role in the development of metabolic and functional abnormality complex at II-type PD and abdominal adisposity. Accumulation of lactate, metabolic acidosis, decrease of glucose efficiency and dysfunction of cardiac hystiocyte calcium pump with the development of diastolic myocardium dysfunction contribute to the development of metabolic disturbances.