bluuebunny/crossref_metadata_2025 huggingface dataset:
GSK-3β and Non-Small Cell Lung Cancer: A Review of Its Role in Disease Mechanisms and Treatment Strategies
Authors: Kristiani Erna
Published: September 2024

Introduction
Recent molecular docking studies have identified potential inhibitors targeting GSK-3β, offering promising avenues for therapeutic intervention. These inhibitors could potentially disrupt the oncogenic signaling pathways mediated by GSK-3β, thereby halting or reversing tumor progression. This literature review seeks to deliver a thorough examination of the current knowledge regarding GSK-3β influence on NSCLC.
Methods
The author carried out an extensive literature review utilizing various electronic databases such as PubMed, Scopus, and Europe PMC. The search keywords included "GSK-3β," "glycogen synthase kinase-3 beta," "non-small cell lung cancer," "NSCLC," "prognosis," "apoptosis," "cell proliferation," "autophagy," "radiosensitivity," "tumor differentiation," and "molecular docking." The findings from the included studies were integrated into a narrative review, emphasizing GSK-3β role in NSCLC pathogenesis, its potential as a therapeutic target, and its utility as a prognostic biomarker.
Results
GSK-3β is a multifunctional serine/threonine kinase involved in various cellular processes, including proliferation, differentiation, motility, and survival. Its expression is associated with NSCLC differentiation, with GSK-3β-negative tumors showing better prognosis. Preclinical studies have identified potential GSK-3β inhibitors with favorable docking scores and ADME profiles for NSCLC treatment. However, targeting GSK-3β for NSCLC treatment faces several significant challenges. One major issue is the broad role of GSK-3β in various cellular processes, including metabolism and cell survival, which increases the risk of off-target effects and toxicity.
Conclusions
GSK-3β has emerged as a critical biomarker in NSCLC, exerting a significant impact on disease progression, treatment response, and prognosis.
Smart Health Infrastructure: Integrating Internet of Things (IoT) with Edge Computing for Enhanced Disease Surveillance and Response
Authors: Soni Palvi , Tandan Gajendra
Published: September 2024

Smart health infrastructure that incorporates the Internet of Things (IoT) and edge computing offers an innovative approach to improving disease response and surveillance Public health emergencies and chronic disease surveillance are two areas where this program is particularly important because of the significant impact that early intervention can have on patient outcomes. Hurdles for the integration of healthcare IoT and edge computing are data privacy and security concerns, performance issues on IoT devices as well as robust network infrastructure needs. To reduce its reliance on computers, Cloud has come up with a plan of introducing Edge Computing-based Context Health Monitoring System (EC-CHMS) which enables faster data analysis and response times by eliminating its use. The healthcare information is locally managed between the networks throughout the system network through edge computing in EC-CHMS that incorporates cloud to manage healthcare information locally between networks within the entire network. This technology can recognize a patient’s life threatening condition by fusing IoT sensors with machine learning algorithms and has numerous possibilities for healthcare applications such as early disease detection, real-time outbreak management, remote patient care among others. Continuous and context-aware health monitoring is possible using this system that supports proactive healthcare interventions towards enhancing overall health delivery efficiency. These results demonstrate that EC-CHMS outperforms traditional cloud-based systems in terms of handling data efficiently and time taken to run the code. To ensure accuracy and reliability of these vital signs, simulation shows how multiple health issues can be handled by it.
Online Counseling Encourages Openness to Help Individuals Dealing with Psychological Disorders
Authors: Hariastuti Retno Tri , Fitriyah Fifi Khoirul , Winingsih Evi , Sukmawati Indah , Afdal  , Hariko Rezki , Purna Rozi Sastra
Published: September 2024

Online counseling can be used to help individuals maintain their mental health. There is a need to test the feasibility and effectiveness of online counseling in treating individuals who experience psychological disorders. The research was carried out through one of the pre-experimental design models, i.e one group pretest-posttest. Participants were twelve individuals consisting of students and communities who were experiencing psychological distress in severe and chronic status who were willing to participate in online counseling programs. Online counseling is administrated through a synchronous and asynchronous format. Feasibility is statistically established based on data on the client’s comfort to express himself and his involvement in the counseling process. The technique used is a percentile with a percentile of 75 (P75) as a minimal condition. Data on convenience is measured quantitatively through scale and engagement data is measured quantitatively based on counseling documents. The effectiveness of counseling is statistically established on the basis of whether or not there is a significant decrease in the status of the client's psychological disorder. The statistical technique used is the t test for correlated samples. Psychological disorders are defined as stress, anxiety, and depression which is being experienced by the client and measured through DASS-21 (depression, anxiety, stress scale version 21 items) in Indonesian version. The study produced two main findings as follows.: (1) online counseling can strongly encourage self-exploration and client engagement; and (2) online counseling is significantly effective in lowering the status of the client's psychological disorders, although the rate of decline in this status is varied between clients.
Adverse Drug Reaction and Pharmacovigilance in Elder Patient’s Health
Authors: Dewangan Hemlata , Bhoyar Naina
Published: September 2024

A pharmacist is a medical expert who is dedicated to helping patients take medications in a safe and efficient manner. Many Indian hospitals do not consider a pharmacist’s responsibility for medication use or their role as a health care provider in clinical practice. The study's first goal is to comprehend how healthcare professionals view and interact with the clinical role of the Pharmacist. According to the study, general practitioners were only made aware of the role of the clinical Pharmacist following an intervention. The study makes the strong recommendation that other hospital-affiliated health care providers be allowed to take part in educational programs on drug-related topics and be open to collaborating with the clinical Pharmacist to improve patient care. According to the current study, pharmacovigilance program implementation in hospitals is crucial for ensuring safe medication use, preventing adverse drug reactions, and, ultimately, improving patient care quality.
The Effect of Supportive Education About Gentle Birth with Audiovisual Media on Readiness to Childbirth in Third Trimester Primigravida
Authors: Anggraini Fritria Dwi , Puspitasari Nunik , Masruroh Nur , Zuwariah Nur , Riantika Nabilla Fitri
Published: September 2024

A third trimester primigravida mother's excessive anxiety indicates a lack of preparation that will negatively impact the mother's, the fetus's, and the delivery process's health. Making birth plans might help a mother feel more prepared for giving birth. The purpose of this study is to ascertain how preparedness for labor is affected by supportive education about gentle birth through the use of audiovisual media. Pre-experimental methodology with a single group pre-test–post-test design was employed in this study. Maternal preparation for labor and supportive education about gentle birth through audiovisual media were the research variables. In June 2023, the Pratama Anugrah Clinic in Surabaya recruited 30 participants for the study, of whom 30 were sampled using total sampling. The study group consisted of primigravida mothers in their third trimester. The questionnaire was the instrument, and the Wilcoxon test with α = 0.05 was utilized for analysis. The findings demonstrated that whereas most respondents (60%) felt well-prepared before receiving supportive education, nearly all respondents (93.3%) felt well-prepared for childbirth after receiving such information. The Pratama Anugrah Clinic Surabaya's mothers' preparedness for childbirth is impacted by supportive education, as indicated by the findings of the Wilcoxon test analysis, which yielded a P=0.003 result. The study concludes that maternal preparedness for childbirth can be positively impacted by supportive education about gentle birth through audiovisual media, leading to an increase in knowledge, information, and maternal readiness.
The Effect of Emotional Freedom Technique on Academic Anxiety and Stress in Nursing Students
Authors: Fitriasari Andikawati , Yulanda Nita Arisanti , Khamida  , Purwanti Nunik , Septianingrum Yurike
Published: September 2024

Due to their numerous academic responsibilities, students may experience elevated levels of stress and anxiety. EFT is a safe, non-pharmacological therapy that is simple to learn and use to reduce anxiety and stress. This study used a one group pre-post test design technique to examine the impact of the Emotional Freedom Technique on academic stress and anxiety in nursing students enrolled in pre-experimental research. This study's participants were nursing students. Using the Simple Random Sampling method, 57 responses made up the sample size. The study's variables included academic stress and anxiety, as well as EFT therapy. Students who exercise 1-2 times a week with meetings four times a month receive EFT therapy; sessions last an additional 15 minutes. The Wilcoxon Signed Rank Test with α = 0.05 was utilized for data analysis. According to the findings, the majority of respondents (56.1%), or 32 people, had moderate anxiety levels before to receiving EFT therapy, and nearly all respondents (93%), or 53 people, had moderate stress. Following EFT therapy, the majority of respondents (56.1%), or 32 people, reported having moderate anxiety, and nearly all (84.2%), or 48 people, reported having moderate stress. It may be inferred from the pre- and post-test results, which showed a significant difference at the 0.05 level of significance and p = 0.000 (0.000 <0.05), that EFT therapy had an impact on nursing students' anxiety and academic stress. Students who have academic anxiety and stress can benefit from EFT therapy.
Artificial Intelligence and Machine Learning in Healthcare Cybersecurity of Current Applications and Future Directions
Authors: Mishra Nidhi , Shivaji Ghorpade Bipin , Barekar Sheetal Sachin , Dari Sukhvinder Singh , Dhabliya Dharmesh , Patil Mukesh
Published: September 2024

Data communication has increased due to the growth of technology-driven services and application deployment. Because there are always security risks to networks, the increasing throughput of networks has also increased the likelihood of cybercrimes. Additionally, the abrupt end of the COVID crisis, which caused nearly all services to go online, has increased awareness of the threat posed by cyberattacks in general. Thus, in the information and technology-driven world of today, reliable communication is crucial. The network is frequently discovered to be vulnerable to a variety of network attacks, such as spoofing, malware, and DDoS attacks. The difficulties caused by intrusions have also been covered in the current work, along with the methods to prevent and detect these kinds of intrusion attempts that have been under investigation for the past few years. Research needs have been identified by presenting and analysing the body of literature currently available on IDS. A hybrid approach has been suggested based on the information to provide a secure communication mechanism and protect the network from intruders. A cyber security strategy based on ABC and 3D CNN architecture is suggested as a solution to this. The qualities that reflect malware and DDoS attack aspects are chosen and optimised using the ABC. Neural networks are trained and classified using the retrieved data. The accuracy, recall, and f-measure analysis of the suggested cyber security method for malware and DDoS node detection were assessed. Comparative investigation demonstrated that the cyber security method was more effective at identifying network attacks.
A Comprehensive Study on Analyzing Business's Immediate Recovery with Public Health
Authors: Roy Jainish , Sachdeva Lalit , Barekar Sheetal Sachin , Dari Sukhvinder Singh , Dhabliya Dharmesh , Patil Mukesh
Published: September 2024

Study investigates the immediate recovery of businesses in the situation of public health crises, focusing on the interplay between health interventions and economic stabilization efforts. Data were collected from 150 business experts and academics through a detailed questionnaire. After that, the data is analyzed using SPSS, Exploratory Factor Analysis (EFA), path analysis, construct reliability analysis, Kaiser-Meyer-Olkin (KMO) and Bartlett's tests which display the connection to the business's immediate recovery. The hypotheses propose that capital issues, economic difficulties, and government support are positively correlated with rapid business recovery. Path analysis reveals significant positive correlations (P<0.001) between capital issues, economic difficulties, and government support with immediate recovery. The results indicate that capital and government support are critical to business recovery plans that are in line with public health priorities, even though capital and economic issues have a large impact on recovery.
Correlation between Tallimetry and Size for Spirometry in Older Adults
Authors: Javier Caiza  , Córdova Paul Adrián Arias , Villalba Paola Ortiz , Armijos Ana Gabriela Solís , Sánchez María Augusta Latta , Chacón Josefina Reales
Published: September 2024

The research focuses on determining estimated spirometric values, measured by wingspan and tallimetry, in addition to analyzing the variability that may or may not exist between these two variables. The study population was 43 older adult participants between the ages of 65 and 90 years, data on weight, height, sex, age, and size were collected. Pulmonary function was evaluated by means of a spirometric examination and the parameters of FEV1, FVC, and Tiffeneau Index were analyzed. The design of the project was prospective-cross-sectional with a quantitative approach of a non-experimental-analytical-relational type. A single evaluation was made with the aforementioned variables that yielded numerical and categorical values and were analyzed with the Chi-square statistical test. Spirometric values were obtained for both tallimetry and wingspan. The statistical analysis yielded a result of p 0.000, which indicates perfect agreement between the variables studied in relation to the true hypothesis of the research, where it is mentioned that there is no variability between the values. In conclusion, the use of wingspan would be the most appropriate alternative to height for lung function analysis.
Engineering Ergonomic Risk Assessment of Karate Choku Zuki Straight Punch
Authors: Alzughialat Mohannad Odeh , Alkhawaldeh Osama Mohammad , Albzeirat Malek Khalaf
Published: September 2024

This study utilizes the Rapid Upper Limb Assessment (RULA) technique to evaluate suggested improvements aimed at enhancing the safety and efficacy of the Choku Zuki (Straight Punch), a high-risk karate exercise. The primary objective is to identify and address potential musculoskeletal issues associated with this technique. Given the prevalence of musculoskeletal injuries in sports, particularly in activities with high intensity like karate, the need for reliable ergonomic risk assessment tools such as RULA is paramount. By applying RULA to analyze the ergonomic aspects of the Choku Zuki punch, this study provides crucial insights into potential areas of concern. It identifies specific postures and movements that may predispose practitioners to injury, allowing for the development of targeted interventions to mitigate risks and enhance safety. Furthermore, this research underscores the importance of integrating ergonomic considerations into sports training regimens to optimize performance and minimize injury risks. Beyond its implications for karate training, the study emphasizes the broader significance of ergonomic assessments in sports science and engineering. It showcases how engineering methodologies can be leveraged to improve the safety, efficiency, and overall performance of sporting activities, fostering collaboration between sports scientists, engineers, athletes, coaches, and healthcare professionals to advance sports performance and safety standards.lities.
Blockchain-Based LSTM Approach for Secure Data Transmission in IoT-Enabled Healthcare System
Authors: Soy Aakansha , Balkrishna Sutar Manisha
Published: September 2024

Blockchain technology can help with a number of issues facing the healthcare sector. Its potential as trust brokers includes the provision of incentive machines and the facilitation of innovative healthcare solutions. Additionally, its potential as trust brokers includes the facilitation of novel business models that offer fresh perspectives on the interactions between patients and providers, among other diverse healthcare stakeholders. Blockchain, for instance, makes incentive structures easier to implement and promotes decentralised trust in patient-centered healthcare models and global health information exchange (HIE). On the other hand, blockchain is characterised as a decentralised network or service that can help remove obstacles in the healthcare sector. The healthcare sector has benefited greatly from the effective resolution of problems relating to adoption and technological obstacles, interoperability and integration with current systems, cost unpredictability, scale, and regulatory compliance through the use of Blockchain technology. This work proposed discusses fault tolerance techniques in relation to sharing health-related data.
Negative Self-Care Behaviours Among Diabetic Patients Bukittinggi, Indonesia
Authors: Srywahyuni Ade , Amelia Dona , Merianti Liza
Published: September 2024

Diabetes mellitus is a chronic multifactorial endocrine disorder that affects approximately 5-10% of adults worldwide. In Indonesia, approximately 10.8 million people, which accounts for 10% of the population, suffer from diabetes. The current treatment considered suitable for diabetes management involves self-care management. Self-management plays a crucial role in achieving blood sugar control, reducing complications, improving quality of life, and lowering hospitalization rates. Negative self-care behaviors frequently observed among diabetes patients include consuming high-fat foods, sugary snacks, non-adherence to diabetes diet protocols. These unhealthy habits make it more difficult to regulate one's own health, which increases the risk of morbidity and death, uncontrolled blood sugar levels, and a decline in quality of life. The purpose of this study is to identify poor self-care practices among type 2 diabetes patients in the Bukittinggi health facilities' service region. Using a deliberate sample technique, a qualitative descriptive study was carried out in seven operational regions of the community health clinics in Bukittinggi, Indonesia. Participants were interviewed in semi-structured interviews, and a chollezi was used to analyze the data. There were 15 people in all, ages 30 to 69, who participated in this study. The participants had been diagnosed with diabetes for a duration of 2 to 21 years. The study identified four themes: unhealthy dietary behaviors, poor medication adherence, preference of unstandardized based herbal medicine, and surrender to Diabetic. Future research should focus on developing appropriate interventions and health promotion strategies
Importance of Pharmacovigilance in Health and Clinical Research
Authors: Bhanja Mrutyunjaya , Vaishnaw Aayush
Published: September 2024

The field of pharmacogenomics has grown to be quite promising for the medical industry. Therefore, it is critical to assess the attitudes and knowledge of healthcare professionals. The study of interindividual differences in DNA sequence linked to pharmacological response is known as pharmacogenomics, or PGx. There have been several attempts to incorporate this area of research into standard therapeutic procedures. Before initiating clinical PGx in a hospital setting, we provide a brief overview of PGx and its function in enhancing treatment outcomes. Prioritization should involve assessing the PGx evidence that is now available, reviewing the medications that are most relevant, and figuring out which variant alleles and drug-gene combinations are the most actionable. Pharmacogenomics, or PGx, is one of the fields of precision medicine with the greatest potential to swiftly transform standard healthcare.Due to the quick advances in PGx knowledge obtained from extensive basic and clinical research as well as the falling costs of laboratory testing, there is presently increased interest in PGx and anticipation of an imminent clinical translation with major therapeutic impact. However, integrating PGx into clinical workflows is not an easy task; multidisciplinary cooperation and thorough procedures are needed. A greater knowledge of unresolved difficulties has resulted from the pioneering models for clinical PGx implementation developed by a number of national and international institutes.
High-Output Heart Failure Secondary to Post-Traumatic Arteriovenous Fistula
Authors: Medicina Cruz Castillo Yessenia Magaly Docente de , Vascular Fejioó Amaya Diana Elizabeth Cirujana , Augusta Solís Serrano María , Juvenal Vasco Martínez Armando , Elizabeth Telenchana Sulqui Rosa , Daniel Pombosa Manobanda Luis
Published: September 2024

Introduction: Arteriovenous fistulas are abnormal connections between the arterial and venous systems that bypass normal anatomical capillary beds. Any device, implement, or projectile that passes through an artery and vein has the potential to lead to one, thereby preventing normal blood flow through the capillary bed. Late complications of untreated arteriovenous fistulas include proximal arterial dilation, venous congestion, congestive heart failure, and distal ischemia. Objective: Describe the clinical manifestations, diagnostic, therapeutic, prognostic complexities and complications present in post-traumatic arteriovenous fistula and its association with heart failure. Material and methods: Retrospective study presentation of a clinical case. Results: The case of a 55-year-old female patient is presented, with a 2-year history of ischemic heart disease and a gunshot wound 20 years ago. Who was admitted for bypass and coronary angiography + cardiac angiography in whom no etiology of his dilated ischemic heart disease was found until Doppler ultrasound and tomography angiography was performed due to recurrence of pain in the lower limbs and changes in skin color, which revealed presence of arteriovenous fistula. The same one that was resolved with distal ligation of the popliteal vein + exclusion of aneurysm. Conclusions: Risk factors for the development of this pathology are difficult to establish. Therefore, the shotgun trauma to the left leg 20 years ago, in addition to her obesity and female sex, led to the formation of an arteriovenous fistula that would gradually produce high-grade heart failure. Endovascular AVF repair is a treatment alternative for those patients considered high risk from anesthesia, those who have a hostile groin due to excessive scar tissue, or who cannot tolerate the consequences of bleeding that can occur with surgical control. of the FAV.
The Effect of Family Empowerment Based on Family-Centered Nursing on the Level of Family Independence in Preventing Stunting in Toddlers in the Simomulyo Community Health Center Working Area, Surabaya
Authors: Nurjanah Siti , Soleha Umdatus , Hanik Umi , Anggraini Fritria Dwi
Published: September 2024

Introduction: Stunting in toddlers is a major public health concern that impacts the next generation. It was suggested that the problems that occurred at the Simomulyo Health Center in Surabaya are mostly the result of parental and family circumstances. But at now, families and parents are unable to carry out their roles to the best of their abilities. The reason for this examination was to explore the relationship between family empowerment and family independence in preventing little child stunting, utilizing the family-centered nursing paradigm as a basis. Method: The research design employed a straightforward random sampling technique, and 154 respondents in total were sampled. Utilizing inclusion and exclusion criteria, 77 respondents were allocated to the intervention bunch and 77 respondents to the benchmark group. The instruments utilized in this experiment were questionnaires. 1) Demographic data; 2) Family assessment using the Family Centered Nursing Model of the Ministry of Health, developed from Friedman's research. This family examination will be conducted with the presence of a health provider. Assess the family's resources and strengths using the SCREEM (Social, Cultural, Religious, Economic, Educational, and Medical) framework. The statistical analysis used the Mann-Whitney test with p0.05 and the Wilcoxon signed rank test. Results: The outcomes showed that there was a significant distinction in the level of family independence between the intervention and control bunches following the intervention. The difference test between the treatment and control groups produced a value of p<0.001 when conducted using Mann Whitney. Conclusion: Family empowerment grounded in a family-centered nursing paradigm can increase the degree of family independence and ward off stunting in toddlers. A later study found that toddler stunting can be avoided with greater family independence. Further research included a sustained coaching program for stunting prevention that spans from the beginning of a marriage to the first 1000 days of life (HPK).
Progressive Muscle Relaxation on Family Anxiety with Hypertension
Authors: Rusdianingseh  , Khafid Muhamad , Maimunah Siti , Afiyah Raden Khairiyatul , Putri Berlian , Nadatien Ima
Published: September 2024

Since hypertension is a chronic condition, long-term care is required. Anxiety within the family is one of the ways that long-term care and the possibility of complications impact the loving family. Extended family stress may lead to subpar treatment for hypertensive individuals, which will impact their pulse. The purpose of this study was to examine what increasing muscle relaxation meant for the anxiety levels of hypertensive families. Analytical methods are utilized in this kind of quasi-experimental study. All households with family members who experience the ill effects of hypertension are the target population. samples from 35 participants in the control group and another 35 participants in the experimental group. The HARS questionnaire was the tool used to gauge the level of anxiety. Using the SPSS software, data management employed the Wilcoxon Signed Ranks Test at a significance threshold of <α (0.05). The outcomes demonstrated that gradual muscle relaxation had an impact on the anxiety levels of the experimental group's families with hypertension. ρ = 0.000 (0.000 <0.05) was the result of the Wilcoxon sign rank test at a significance level of 0.05. The control group's Wilcoxon sign rank test result, at a significance level of 0.05, was ρ = 1.000 (1.000 > 0.05), indicating no effect of progressive muscle relaxation on anxiety. According to the study's findings, gradual muscular relaxation can diminish anxiety. To bring down anxiety levels, this technique can be utilized as a non-pharmacological therapy.
Integrating Pharmacists into Public Health Initiatives: Challenges and Opportunities in India
Authors: Pandey Rashmi , Chandu Himanshu Nirmal
Published: September 2024

Since most people can visit pharmacies easily and don't need an appointment, they are naturally regarded as the primary choice for healthcare professionals in society. Pharmacists have the potential to be an important link in the global healthcare system. Since not everyone is served by public health services, pharmacies and private healthcare providers can play a significant role in the healthcare system. This also applies to the nation of India, which is inhabited by almost 1.3 billion people. The majority of India's chemists, both in the public and commercial sectors, are underutilised resources despite their extensive presence. The purpose of this study was to assess the emphasis on patient care and public health in pharmacy education, as well as the participation of pharmacists in national public health programmes (NPHPs) in India. The aim of the research was to ascertain the extent to which pharmacist education may aid in this transition and the locations where pharmacists could participate more actively in national public health campaigns. The public health and patient care components of the pharmacy curriculum in India are being evaluated for the first time with this study. It will be helpful to statutory organisations and curriculum reform committees in India and other countries where the functions of chemists are expanding to include public health and patient care.
Psychological Well-Being in Elementary School Teachers
Authors: Izzati Umi Anugerah , Lestari Gunarti Dwi , Suhartini Ratna , Ramadhani Bima Yatna Anugerah
Published: September 2024

It is the responsibility of educators to mentor and assist students as they learn and develop behaviors that will help them succeed. Teachers' mental health frequently suffers as a result of the workload they bear in order to support students' achievement. Teachers' psychological health may be impacted by this. The purpose of this study is to ascertain the psychological well-being dynamics of an elementary school teacher in the Surabaya city. Twelve primary school teachers served as the subjects of this qualitative study. Three procedures were used to analyze the data: data reduction, data presentation, and conclusion drafting. The study's findings indicate that Surabaya's elementary school teachers' general psychological health falls within the "good" range. Additionally, out of all the dimensions, the dimension of having positive interactions with other people is the highest. In the meantime, there are two moderate elements of psychological well-being: personal progress and life purpose. The study's conclusion is that in order for the on-duty teachers to properly carry out their duties, the school must continue to support a number of psychological well-being characteristics.
Innovative Earthquake Warning System for Enhancing Public Health Prevention
Authors: Nandy Manish , Dubey Ahilya
Published: September 2024

An earthquake is a sudden ground shaking caused by tectonic activity, posing significant risks to human safety. Effective public health strategies focus on minimizing damage, providing timely warnings, and ensuring response plans to reduce health impacts during seismic events. The purpose of this research is to establish an innovative earthquake warning system for enhancing public health prevention. In this study, we propose a novel Mexican Axolotl Optimization-tuned Adjustable Support Vector Regression (MAO-ASVR) for accurately detecting the earthquake incidents. Our model integrates Internet of Things (IoT) technology to collect data from various sensors deployed across seismically active regions. The obtained signal data is pre-processed using Noise Filtering technique. In our proposed model, MAO optimization algorithm iteratively fine-tunes the ASVR architecture for enhancing the detection accuracy. The system activates an early warning alert within seconds of detecting seismic activity and sends notification, thereby minimizing potential damage. During the findings analysis phase, we evaluate our model's performance across various parameters. In addition, we also performed comparative analyses using diverse existing methodologies such as MAE with 0.397888, PMRE with 19.81432 errors, RMSE with 0.509074 errors. The findings demonstrate excellence and effectiveness of the suggested model.
Intelligent Health Assessment Based on Communication and AI Technologies for Public Health
Authors: Sinha Anupa , Kumar Yalakala Dinesh
Published: September 2024

Automating EEG pattern categorization in public health helps in the early detection of epilepsy and other brain illnesses. However, present methods have difficulties in reaching excellent accuracy and adaptability. This study utilizes a hybrid strategy that incorporates Spider wasp-tuned Convolutional neural network (SW-CNN). Convolutional neural networks (CNNs) use complex feature extraction from EEG data, and Spider wasp optimization (SWO) improves network parameters by comparing them to the pursuing and developing behaviors of spider wasps. By enhancing classification accuracy, precision, recall, and F1-score measures, the combined effect seeks to achieve significant improvements over conventional techniques. The research concludes that the SW-CNN hybrid model performs better at differentiating between non-seizure activity and epileptic seizures. This strategy improves diagnosis accuracy and efficiency in public health, resulting in better patient outcomes and treatment planning. Effective transmission of such results is critical for furthering clinical diagnosis and research in neurological diseases.
An Analysis of Consumer Awareness Regarding Jan Aushadhi Kendras
Authors: Vayalambron Lijina , O C Sishina
Published: September 2024

India has made significant advancements in various health aspects, including an increase in the life expectancy of both men and women, low infant and maternal mortality rates, improved immunization coverage, and the elimination of diseases like polio and smallpox. According to the World Health Organization, around 5.8 million Indians succumb to diseases like diabetes, cancer, stroke, and heart and lung diseases. Non-communicable diseases (NCDs) pose a substantial health challenge in India, with one out of every four Indians dying before the age of 70 due to an NCD. The Indian healthcare system is grappling with rising healthcare costs, which disproportionately burden the poor, as well as the emergence of new diseases and non-communicable diseases. Approximately 100 million Indians fall into poverty each year due to high healthcare expenses, with out-of-pocket spending constituting over 50 percent of this burden. To reduce healthcare costs, the government has established Jan Aushadhi Kendras, which offer generic medicines with the same composition as branded ones at affordable prices. A recent study focused on identifying the key factors influencing the purchase of generic drugs from Jan Aushadhi medical stores, public awareness of these stores, and consumer satisfaction. The study found that 40 percent of the public is unaware of Jan Aushadhi, and consumers opt for generic medicines due to their affordability, even though the quality is lower than that of branded drugs. Jan Aushadhi Kendra is known for selling significant quantities of sanitary pads. While most consumers are satisfied with Jan Aushadhi products, some express dissatisfaction due to differences in quality and composition. Government agencies and health departments must enhance the quality of generic medicines and educate healthcare professionals and the general public about them.
Investigation of Pharmacological Screening Techniques for Diabetes Mellitus
Authors: Dewangan Bhuneshwari , Barsagade Monika
Published: September 2024

Diabetes is the medical term for a condition in which the body fails to generate or use insulin as intended, leading to high blood sugar levels. Both in-vitro and in-vivo techniques are employed to assess the antidiabetic potential of synthetic or natural compounds that have been extracted from conventional plants. The rat paw oedema method is frequently used to screen anti-inflammatory medications. The use of animals in this procedure has drawbacks related to ethical concerns. We proposed an in vitro system in this context that would not have these drawbacks. Rat in vivo experiments are frequently used to screen anti-hyperlipidemic medications. Pharmacological screening currently entails testing novel chemical entities as plant extracts or any other type of material (synthetic or semisynthetic) in isolated preparations before testing on entire animals. Rats and mice are typically used, but occasionally higher animals like dogs and monkeys are as well. These techniques have been used to assess the majority of medications now used in therapy. Wherever possible, non-animal alternatives are being developed. Pharmacologists' constant struggle is to reconcile in vitro and in vivo results. A thorough grasp of the in vivo performance is one of the main objectives of pharmacological screening. Therefore, it would be praiseworthy to establish in vitro assessments that might be connected to in vivo performance.
Legal Issues in Infectious Disease Control and Prevention Perspective
Authors: Agarwal Meenakshi Rani , Farooqui Alber Ahmed
Published: September 2024

The Indian system of safeguarding an individual's health has a lengthy history. It has gained notoriety across the globe in the field of medical systems. The commercialization of medications and the medical profession, along with the passage of time and advancements in science and technology, enhanced the duty of physicians and contributed to the daily rise in medical negligence lawsuits. The government has established a number of committees to examine public health-related issues, and these committees have produced a number of suggestions aimed at enhancing India's healthcare system. The world came to understand that one of every person's most basic necessities is their health. The right to health is recognised by almost all human rights treaties. In addition to the obvious absence of disease, the term "health" also refers to the availability of sufficient medical treatment and facilities, which not only guard against illness but also guarantee the support of a robust labour force that is necessary for economic growth. Therefore, health is more than just the absence of illness or disability; it is a state of total physical, mental, and social well-being. The International Bill of Rights and the United Nations both recognize the right to health as an international right. Every State in the globe is required by the UN Charter to fulfil certain obligations to accomplish the goal, and in this regard, governments must cooperate with the UN Organisation in both solo and collective acts.
Phonocardiogram Signal Analysis Based Premature Cardiac Influence Detection using Resnet50 CNN for Public Health Protection
Authors: Sinha Anupa , Kumar Yalakala Dinesh
Published: September 2024

Phonocardiogram (PCG) signal analysis plays a crucial role in the early detection of cardiac abnormalities, which is essential for public health protection. The premature disease prediction is tedious because the feature analysis takes place dimensionality problems which leads poor accuracy. The prevailing ensemble learning models’ methods doesn’t concentrate disease margin facts and properties during classification produce higher false rate because for adjusting feature margins gets lower accuracy.  To resolve this problem, we propose a efficient Fuzzy c-means feature modality based Resnet50-RNN to detect premature cardiac influence detection for improving public health. The research proposes a method for premature cardiac influence detection using a ResNet50 Convolutional Neural Network (CNN) model for early prediction of heart disease. To address the issue of imbalanced data, Synthetic Minority Oversampling Technique (SMOTE) is employed for preprocessing. The Cardiac Disease Influence Rate (CDIR) is then used to identify the maximum deficiency-affected feature margins. Fuzzy c-means is utilized to select the mutual features associated with the heart disease influence rate. The ResNet50 CNN model is employed for classification, enabling the prediction of disease margins by risk category. The proposed system effectively identifies the disease based on the disease-affected scaling margin, leading to early disease impact prediction with higher accuracy, specificity, F1-measure, and lower false rates compared to other existing systems. The implementation also demonstrates reduced time complexity.
Role of Wearable Health Devices in Public Health: Developing Flexible Electronics for Seamless and Continuous Health Monitoring
Authors: Haval Abhijeet Madhukar , Afzal Md
Published: September 2024

The strategy for personalized medicine is the incorporation of regular health check-ups and wearable health devices into public health campaigns. These innovations have the potential to reduce the burden on healthcare systems by enabling early detection, improved management of chronic conditions, and provision of real-time personal health data to individuals. To achieve this, problems related to the accuracy of devices used, security of data stored in these devices, compliance with usage requirements by consumers, and relations with the current healthcare system must be addressed. A solution to these barriers has been proposed as a Non-Invasive Flexible Sensors for Health Monitoring (N-IFS-HM) approach which involves making sensors that are lightweight, attractive looking, and provide accurate continuous health information without disturbing the users during their daily activities. Through detailed simulation studies conducted in different healthcare settings, this paper examine the dependability and effectiveness of N-IFS-HM implementation. Consequently, based on simulation results done on delicate sensors such as these, vital signs, activities and minimal discomforting healthcare products can be traced accurately. According to this finding, wearable digital technology with sophisticated flexible electronics can revolutionize how public health is assessed.
Validity And Realibility Of The Knowledge, Attitude And Practice (Kap) Questionnaire On Hexagonal And Olympic Barbell Deadlift Among Young University Students
Authors: Adnan Mohd Aizzat , Nadzalan Ali Md , Mohd Nasir Muhammad Zulqarnain Bin , Zamri Fatin Nur Shahira , Vasanthi Rajkumar Krishnan , Pavlović Ratko
Published: September 2024

An instrument for assessing the Knowledge, Attitude, and Practice (KAP) regarding hexagonal and Olympic barbell deadlift among young university students is crucial for identifying any gaps in KAP. This assessment can assist in developing specific educational interventions, enhancing training programs, improving overall strength and conditioning outcomes, and mitigating health risks. The objective of this study was to create and verify a questionnaire, specifically designed for young university students, that assesses knowledge, attitudes, and practices (KAP) related to hexagonal and Olympic barbell deadlift exercises. A study employing purposive sampling was undertaken among a cohort of 242 young university students in Malaysia. This questionnaire was derived from a previous study and enhanced with additional components related to hexagonal and Olympic barbell deadlift. The verification of content validity, construct validity, and reliability was conducted utilising several tests. All the items in the questionnaire contribute to a minimal factor structure, as indicated by the results of a rotational component matrix. The Kuder-Richardson 20 (KR-20) coefficient for the knowledge domain was 0.73, which is regarded satisfactory. The Cronbach's Alpha values above 0.70, indicating strong reliability. However, they were lower than the overall Cronbach's Alpha value of 0.965 for the practice domain. Therefore, no item needed to be removed. This questionnaire demonstrates robust validity and reliability, making it suitable for assessing knowledge, attitudes, and practices related to hexagonal and Olympic barbell deadlift.
Ai-Driven Prediction Models For Medical Image Enhancement And Analysis Using Deep Learning
Authors: Sendil M Sadish , Kumar A Senthil , K Valarmathi , Kumar R. Sampth , Gayathri R. , Nagesh Puvvada
Published: September 2024

Thyroid diseases, including cancer, demand for accurate medical imaging for diagnosis and treatment direction. Important MRI imaging of the thyroid occasionally suffers with poor resolution and noise. Conventional imaging enhancement techniques may not be able to effectively solve noise or capture small features required for a successful diagnosis, therefore lowering the image quality and diagnostic accuracy. For feature extraction and classification, we provide an artificial intelligence prediction model on multi-scale deep convolutional neural network (CNN). Our method reduces noise and solves resolution enhancement, hence improving thyroid MRI images. For this work we used a bespoke CNN architecture and a 500 thyroid MRI image collection. Not only considerably outperforming current techniques, our model generated a Structural Similarity Index (SSIM) of 0.89 and a Peak Signal-to---- Noise Ratio (PSNR) of 32.5 dB. The improvements brought diagnosis accuracy 15% above more traditional techniques.
The Function of Cadres in Putting Child Development Stimulation, Detection, and Early Intervention Programs into Practice
Authors: Dewi Uke Maharani , Novianti Hinda , Munjidah Annif , Masita Elly Dwi , Zuwariah Nur
Published: September 2024

The East Java province's child health care coverage in 2020 was 83.3%, a decrease from 2019. In Surabaya, the coverage in 2019 was 91.59%, but it still did not meet the 2020 Minimum Service Standards (MSS) target of 100%. The inadequate implementation of programs for early detection, stimulation, and intervention in child growth and development (SDIDTK) is one factor contributing to the failure to meet this objective. For these initiatives to be successful at the Posyandu level, community health workers, or cadres, must be involved. The objective of this research is to look at how the SDIDTK programs use cadres. There were 71 respondents in the cross-sectional research, which used an observational analytic methodology. Out of the seven roles, only two were performed by all cadres (71 individuals): determining head circumference, weight, height, and upper arm circumference; providing the information into the early detection form for assessing newborn growth and creating a visual representation of the results. In the mother and child health book, two roles were not performed by any of the cadres. The first responsibility was to complete the Early Detection of Child Growth and Development form by providing the child's identity. The second role was to use the child development checklist to observe and mark the child's developmental abilities as appropriate (√) or not appropriate (-).