bluuebunny/crossref_metadata_2025 huggingface dataset:
Membangun kepemimpinan inklusif: studi kasus manajemen layanan inklusi pada sd negeri 25 Banda Aceh
Authors: Aishah Aishah , Nurdin Diding , Saâ€™ud Udin Syaefudin , Meirawan Danny , Nuphanudin Nuphanudin
Published: January 2025

Penelitian ini bertujuan untuk mengeksplorasi dan menganalisis implementasi kepemimpinan inklusif dalam manajemen layanan pendidikan inklusi di SDN 25 Banda Aceh. Fokus penelitian mencakup bagaimana kepala sekolah menciptakan lingkungan yang inklusif, membangun kolaborasi dengan berbagai pemangku kepentingan, dan mengatasi tantangan dalam pelaksanaan pendidikan inklusi. Penelitian ini menggunakan pendekatan kualitatif deskriptif dengan desain studi kasus. Data dikumpulkan melalui wawancara mendalam, observasi, dan analisis dokumen dari kepala sekolah, guru, orang tua, serta pihak komunitas lokal. Hasil penelitian menunjukkan bahwa kepemimpinan inklusif di SDN 25 Banda Aceh telah berhasil menciptakan budaya sekolah yang mendukung keberagaman melalui kolaborasi intensif dengan para pemangku kepentingan. Kepala sekolah memainkan peran sentral sebagai fasilitator, mediator, dan inovator dalam mendukung program inklusi. Namun, penelitian ini juga mengungkap beberapa kendala, seperti keterbatasan sumber daya, kompetensi guru, dan persepsi masyarakat terhadap pendidikan inklusi. Kendala-kendala ini diatasi melalui pendekatan kolaboratif dan pelibatan aktif komunitas sekolah. Kebaruan penelitian ini terletak pada identifikasi strategi kepemimpinan inklusif yang efektif dalam konteks pendidikan inklusi di Indonesia, khususnya di Aceh, yang memiliki karakteristik sosial-budaya unik. Penelitian ini memberikan kontribusi signifikan baik secara teoritis maupun praktis dengan menawarkan kerangka kerja kepemimpinan inklusif yang dapat diadaptasi di sekolah lain. Implikasi praktis dari penelitian ini adalah penyusunan rekomendasi strategis untuk memperkuat tata kelola pendidikan inklusi, termasuk pelatihan guru, pengembangan kebijakan berbasis bukti, dan penguatan partisipasi komunitas.
Case study of social marketing implementation in covid-19 promotion media and public knowledge of covid-19 in Jayapura city
Authors: Zainuri Agus , Putra Mifta Fariz Prima , Irap S. Piter , Indrayani Ervina
Published: January 2025

This research is based on the critical role of social marketing in raising awareness and promoting healthy behaviors during the COVID-19 pandemic, particularly in Jayapura City, where challenges persist in disseminating effective information and influencing public behavior regarding health protocol adherence. The study aims to analyze the implementation of social marketing through promotional media, such as posters and health protocols displayed in public areas, in enhancing knowledge and influencing behavioral changes among the residents of Jayapura City in COVID-19 prevention. A qualitative case study method was used to evaluate the implementation of social marketing in COVID-19 promotional media and its impact on public knowledge in Jayapura City. Data collection was conducted through semi-structured interviews with respondents from diverse social backgrounds, as well as direct observation of promotional media distributed throughout the city. The findings reveal that while promotional media, such as COVID-19 posters and health protocols displayed in public areas, succeeded in improving the public's basic understanding of the importance of health protocols, there were significant barriers to the consistent application of such behaviors. Factors such as limited access to information, a lack of in-depth understanding, and social resistance to behavioral changes posed considerable challenges to enhancing the effectiveness of the campaign. The research also found that while the campaign positively impacted awareness levels, a more integrated and contextual approach is needed to achieve comprehensive behavioral change among the community.
Ragam Layanan Pendidikan Inklusif Dan Bentuk Pelibatan Orang Tua Anak Berkebutuhan Khusus
Authors: Nela Yunita Wa Ode , Diana Diana , Kurniawati Yuli
Published: January 2025

Implementasi pendidikan inklusif di Indonesia masih bervariasi disetiap daerah, termasuk  di Kota Kendari. Hal ini disebabkan beberapa kendala yang meliputi kebijakan, masih kurangnya ketersediaan tenaga pendidik yang terlatih, serta sarana dan prasarana guna mendukung kebutuhan peserta didik berkebutuhan khusus. Ketercapaian potensi anak di sekolah inklusif bukan hanya menjadi tanggung jawab guru saja tetapi juga menjadi tanggung jawab orang tua sebagai lingkungan pertama dan utama anak di rumah. Tujuan penelitian ini difokuskan pada ragam layanan pendidikan inklusif dalam model kelas sesuai tingkat kebutuhan peserta didik, bentuk pelibatan orang tua anak berkebutuhan khusus, serta faktor pendukung dan penghambat terlaksananya ragam layanan pendidikan inklusif dan bentuk pelibatan orang tua anak berkebutuhan khusus. Penelitian dilakukan dengan pendekatan kualitatif dengan jenis studi kasus. Sumber data primer penelitian ini adalah kepala sekolah guru kelas, shadow teacher, dan orang tua. Sumber data sekunder penelitian ini adalah dokumen-dokumen sekolah seperti kurikulum, fasilitas pendukung, dan program sekolah. Teknik analisis data penelitian ini menggunakan model analisis interaktif yaitu melakukan pengumpulan data, reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian ini menunjukkan bahwa: (1) pelaksanaan ragam layanan pendidikan inklusif di lembaga PAUD meliputi model kelas, pendekatan pembelajaran, layanan khusus, sarana dan prasarana serta pembiayaan. (2) bentuk pelibatan orang tua anak berkebutuhan khusus yaitu kontribusi dan kebutuhan. (3) faktor pendukung dan penghambat berupa dukungan dan tantangan yang muncul di lingkungan sekolah dan di rumah.
Konstruktivisme Model Pembelajaran Kognitif Moral Melalui Aplikasi “Dimo” Untuk Meningkatkan Kemampuan Moral Decision Siswa Sekolah Dasar
Authors: Faiz Aiman , Fadly Aris
Published: January 2025

To offset the concerns that arise due to changes in human behavior caused by rapid and unstoppable technological advances, the field of education needs to provide various reinforcements, one of which is through the learning process. Research to see the improvement of elementary school students' moral decisions through the cognitive moral development model assisted by the "Dimo" application on an Android smartphone. This study uses a pre-experimental design One - Group Pretest-Posttest. The informants of this study were 31 6th grade students at SDN 4 Kenanga, Cirebon Regency. This study resulted in differences in pre and post tests tested on 31 students. The pre-test of the majority of students was in the pre-conventional stage 2 category with 95 choices with a percentage of 61.2%. After treatment and presentation of the "Dimo" application media as a learning medium, 75 students' answers were in the conventional stage 2 with a percentage of 48.3%. These results indicate that with the help of the "Dimo" moral dilemma application media, students' moral considerations and moral decision making can improve. This means that the use of application media for students can provide a complex understanding of the problems of moral dilemmas presented because they are more concrete in audio-visual form. This is also in accordance with the characteristics of the current generation of students who are closely related to technology. This study provides recommendations that with active and varied models, students can better understand the context of the learning presented.
Penggunaan Ifdil perceptual light technique (IPLT) dengan ayat-ayat Al-quran
Authors: Miftahhuddin Miftahuddin , Suhaimi Suhaimi  , Cherly Nadifa  , M. Fahli Zatrahadi  , Suhertina Suhertina  , Rahmad Rahmad  , Istiqomah Istiqomah  , Ifdil Ifdil
Published: January 2025

This study aims to evaluate the effectiveness of the Ifdil Perceptual Light Technique (IPLT) combined with Qur'anic verses in enhancing clients' mental and spiritual balance. The research employs a case study approach with qualitative methods, involving in-depth interviews and observations of six participants, consisting of two therapy experts and four clients from Padang and Pekanbaru. Data analysis was conducted using NVivo software to identify relevant key themes. The study results revealed seven main themes, including the integration of spirituality and IPLT technology, the role of sensory elements in therapy, client responses to the therapy, success in mental and spiritual recovery, challenges in implementation, personalized therapy based on client needs, and perspectives on the future of holistic therapy. The key findings indicate that integrating IPLT with Qur'anic verses can help reduce anxiety levels, enhance spiritual connection, and create a deeper therapeutic experience. However, the study also highlights challenges in balancing technological and spiritual elements, as well as the importance of personalizing sensory elements such as light intensity and sound for each client. The implications of this study include the development of technology-based therapies tailored to clients' spiritual values, as well as recommendations for counseling services to create more holistic and inclusive approaches. These findings are particularly relevant for communities with strong cultural and religious backgrounds, such as those in Padang and Pekanbaru.
Hyperuricemia, use of antituberculosis drugs, and liver injury: case report
Authors: Yuwantari Vina , Oktafiyani Nur , Ningrum Nurmelinda Hadi , Pristantiningtyas M. Hari , Dharma Herya Putra , Muchlis Muhammad , Pratama Jainuri Erik , Herawati Fauna , Setiadi Adji Prayitno , Gondokesumo Marisca Evalina
Published: January 2025

Anti-tuberculous drug can cause idiosyncratic drug-induced liver injury (DILI). Considering the benefit risk, there will discontinuation therapy and rechallenge after symptom resolve. In addition to anti-tuberculosis drugs, liver injury can occur in patients with hyperuricemia. We report a 60-year-old male patient who had just used the initiation phase of OAT for 20 days experiencing hepatotoxic side effects characterized by complaints of nausea and vomiting for one week. Liver function examination results were normal with AST 23 u/L and ALT 9 u/L. OAT administration was temporarily stopped and started gradually with 150 mg rifampicin, 150 mg isoniazid and 500 mg ethambutol. The second day after using OAT again, given the full dose of 300 mg rifampicin, 300 mg isoniazid and 1000 mg ethambutol. The patient's condition improved after this modification of therapy so that therapy with three anti-TB drugs was continued until he was discharged from the hospital.
Potential dyes from edible mushrooms for human health
Authors: Budipramana Krisyanti , Ratih Ratih , Budi Pramana Yanatra
Published: January 2025

Colors (dyes or pigments) have been applied in many sectors of human life, such as textile industries, food, and medicine, thus becoming a crucial factor that cannot be neglected. The origin of color can be obtained from nature or synthetic sources. Nowadays, synthetic colors are used more often than natural ones. However, the use of synthetic colors needs to be considered as they have the potential to cause health problems and contribute to waste issues. On the other hand, natural color sources are dominated by the plant kingdom, such as mushrooms, which are advantageous for health, more economical, and environmentally friendly. The method used in this review was to explore the literatures that discus dyes or pigments from macro fungi or mushrooms. Furthermore, the dyes or pigments were classified from edible or medicinal mushroom, then dyes or pigments were categorized based on their chemical structure. Mushrooms of various genera and species produce different colors that belong to constituent melanin, terpenoids, carotenoids, quinone, styrylpyrone, azulene, and pteridine. Therefore, natural colors are very promising for application in human health, due to their active compounds potency as anticancer, anti-HIV, antioxidant, and antimicrobial. In addition, pigments containing azulene structures from mushrooms are developed as solar cells and UV protection.
Post-vaccination SARS-COV-2 IgG Level: An evaluation study on 2 Area In Indonesia
Authors: Bekti Heri Setiyo , I Gusti Agung Ayu Dharmawati  , Nur Habibah  , Fusvita Merdekawati  , Ganjar Noviar  , I Putu Suiraoka  , Luh Putu Rinawati  , Rike Syahniar  , M. Ibraar Ayatullah
Published: January 2025

Corona Virus Disease (COVID-19) caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has become a global pandemic. Currently there is no effective treatment for this disease, vaccination is one way to deal with this disease. Antibodies that are formed after vaccination are expected to provide protection for everyone. This study was to determine the levels of IgG antibodies formed after SARS-CoV-2 vaccination. 87 respondents were examined in this study using blood samples. Measurement of antibody levels using the CLIA method. The results obtained show that the average level of antibodies formed is 193.355 BAU/ml. 65 respondents who received 3 doses of vaccine (199.652 BAU/ml) had higher antibody levels than respondents who received two doses of vaccine (175.531 BAU/ml) and 1 dose of vaccine (158.365 BAU/ml). Antibody levels in respondents who were examined between 0-6 months after vaccination (202.827 BAU/ml) had higher levels than respondents with a period of more than six months (186.010 BAU/ml). From the study results, data was obtained that the antibody levels in recipients of three vaccine doses were higher so that they could provide sustainable protection against COVID-19. Therefore, the COVID-19 vaccine booster should give to all people to provide protection against COVID-19.
High-dose glucocorticoids inducing hyperglycemia in patients with diabetes mellitus experiencing recurrent ischemic stroke attacks: A case report
Authors: Zahro Fatimatuz , Sugesti Tita , Hermawati Siska , Pristantiningtyas M. Hari , Dharma Herya Putra , Muchlis Muhammad , Pratama Jainuri Erik , Herawati Fauna , Prayitno Adji , Gondokesumo Marisca Evalina
Published: January 2025

Stroke is an acute and focal neurological syndrome characterized by clinical deficits resulting from vascular injuries such as infarction or hemorrhage in the central nervous system. Given the prevalence of multiple comorbidities among stroke patients, they often find themselves on more than five medications, falling into the category of polypharmacy. Beyond treatments aimed at improving stroke outcomes and managing comorbid conditions, the presence of additional diseases may necessitate new therapies, potentially leading to side effects that can intersect and exacerbate the existing disease. This case report aims to present instances of hyperglycemia in stroke patients undergoing high-dose glucocorticoid therapy and discuss potential strategies to address this issue. In this particular case, human insulin was selected to rapidly control the patient's hyperglycemic condition. Subsequently, adjustments to basal and bolus insulin doses were made based on the frequency of use and duration of action of the glucocorticoid, specifically methylprednisolone. In conclusion, the hyperglycemia induced by glucocorticoids was identified through postprandial sugar monitoring, necessitating treatment through modifications to basal and bolus insulin doses. Strategies for managing hyperglycemia should be tailored to the pharmacokinetics of glucocorticoids and insulin.
Optimizing DNA extraction methods for enhanced detection of pathogenic Leptospira spp. in cultures using PCR
Authors: Aprilia Kiki , Mulyanto Arif , Dhanti Kurnia Ritma , El Khobar Korri , Handayani Farida Dwi
Published: January 2025

Leptospirosis is a worldwide zoonosis caused by Leptospira interrogans. Laboratory diagnosis of leptospirosis can be done through sample culture. However, microscopic observation of positive Leptospira spp. culture need to be supported by molecular detection to confirm the presence of pathogenic Leptospira spp. This study aimed to compare the effectiveness of two DNA extraction kits, from QIAGEN and Zymo Research, to extract bacterial DNA genome from positive Leptospira spp. culture for downstream molecular detection. This study is an analytical observational study with a cross-sectional design conducted in June-September 2023, and part of the PESTO-RITA 2023 study. Fourteen identified positive Leptospira spp. culture, with Leptospira spp. movement under dark field microscopy, was used for DNA extraction using both extraction kits. QIAGEN kit yielded higher mean DNA concentration (0.900±0.161 vs 0.790±0.167 log10 µg/mL, p>0.05) and better DNA purity (1.854 vs 1.632, p<0.05) than the Zymo Research kit. PCR results, targeting the lipL32 gene, showed that two samples extracted with QIAGEN and one sample extracted with Zymo Research were positive for pathogenic Leptospira spp. Our preliminary results showed that QIAGEN kit yielded better DNA concentration and purity from positive Leptospira spp. culture.
Effectiveness of ethanol extract of Morinda citrifolia L. as an anti-inflammatory: A preclinical study
Authors: Mega Hayati  , Ali Napiah Nasution  , Ermi Girsang  , Adek Amansyah  , Fioni
Published: January 2025

The inflammatory response is triggered by infections or tissue damage, often requiring effective anti-inflammatory treatments. Morinda citrifolia L. (noni fruit) contains bioactive compounds such as flavonoids, steroids, and triterpenoids with potential anti-inflammatory properties. The aims of this research to evaluate the anti-inflammatory effects and optimal dosing of ethanol extract of noni fruit in reducing paw edema and improving histopathological conditions in male rats induced with Complete Freund's Adjuvant (CFA). This experimental study involved 30 male rats divided into six groups: normal control, negative control (CFA-only), positive control (triamcinolone 0.72 mg), and three treatment groups receiving noni fruit extract (150, 300, 600 mg/200 g BW). Edema volume was measured using a plethysmometer, and histopathological analysis of joint tissues was conducted. Noni fruit extract significantly reduced edema volume, with 600 mg/200 g BW being the most effective dose. However, histopathological analysis revealed persistent inflammatory cell infiltration and synovial hyperplasia in treated groups, indicating incomplete tissue repair compared to triamcinolone. Ethanol extract of noni fruit demonstrates significant anti-inflammatory effects, particularly at higher doses, but is less effective than triamcinolone in resolving tissue inflammation.
Therapeutic potential of Cinnamomum burmannii bark extract in reducing Malondialdehyde (MDA) levels in MSG-induced wistar rats: a preclinical study
Authors: Afrianti Dina , Wahyudi  , Ririh Jatmi Wikandari  , Rodhi Hartono  , Erisa Febriyani  , Egy Sunanda Putra
Published: January 2025

Increased consumption of monosodium glutamate (MSG) is associated with various health risks, including cardiovascular and neurological disorders. MSG triggers an increase in reactive oxygen species (ROS), the end product of lipid peroxidation produced when ROS increases is Malondialdehyde (MDA), On the other hand, interleukin 10 (IL-10) reduces the inflammatory effects in infectious conditions that can cause potential tissue damage. This study investigated the effect of cinnamon bark extract (Cinnamomum burmannii) on MDA and IL-10 levels in MSG-induced Wistar rats. Experiment with Post test only control group design was conducted. The number of samples was 24 male Wistar rats divided into 4 groups. KN healthy rats, K (+) rats were only induced by MSG, P1 rats were induced by MSG and given cinnamon bark extract at a dose of 100 mg, P2 rats were induced by MSG and given cinnamon bark extract at a dose of 200 mg. The average results showed a decrease in MDA levels after 14 days of treatment, one-way ANOVA test p = 0.001 (p <0.05) showed a significant difference in MDA levels KN 2.37 mg/ml ± 0.14, K+ 2.47 mg/ml ± 0.24, P1 2.32 mg/ml ± 0.20, and P2 0.84 mg/ml ± 1.07. Meanwhile, the average IL-10 levels showed no significant difference with one-way Anova test p = 0.127 (p <0.05) in the KN group, IL-10 levels were 93.25 pg / ml ± 25.01, K (+) 112.89 pg / ml ± 43.89, P1 69.48 pg / ml ± 12.83 and P2 93.29 pg / ml ± 12.11. Administration of cinnamon bark extract can reduce MDA levels in rats induced by MSG, but has no significant effect on IL-10 levels.
Evaluation of the anti-acne effectiveness of Andaliman (Zanthoxylum acanthopodium DC) nanoemulgel in propionibacterium acnes-induced male wistar rats
Authors: Tanessa Micella , Ginting Chrismis Novalinda , Chiuman Linda , Masdalena  , Hutagalung Mangatas Halomoan Parluhutan
Published: January 2025

Acne vulgaris is an inflammatory disorder of the pilosebaceous unit, characterized by lesions such as comedones, papules, pustules, nodules, and cysts. This study aimed to assess the effectiveness of Andaliman Extract Nanoemulgel (Zanthoxylum Acanthopodium DC) in treating acne lesions in male Wistar rats (Rattus Novergicus) induced with Propionibacterium acnes. This experimental involved 30 male Wistar rats aged 6-8 weeks, weighing 150-200 grams, divided into 6 groups: 1) normal, 2) negative control (P. acnes induction and base gel), 3) positive control (P. acnes induction and Mediklin TR gel), 4) Treatment 1 (P. acnes induction and 2% Nanoemulgel), 5) Treatment 2 (P. acnes induction and 3.5% Nanoemulgel), and 6) Treatment 3 (P. acnes induction and 5% Nanoemulgel). Nanoemulsion application was carried out for 10 days to evaluate the healing of acne lesions on the skin of Wistar rats. Results showed that Andaliman Extract Nanoemulgel effectively healed lesions caused by Propionibacterium acnes. In conclusion, Nanoemulgel with Andaliman fruit extract at concentrations of 2% and 5% demonstrated the highest effectiveness in anti-acne treatment.
Adolescent Vaginal Hygiene and Trichomonas vaginalis: A Focused Study in Balongbendo Village, Sidoarjo, East Java, Indonesia
Authors: Acivrida Mega Charisma  , Farida Anwari  , Bagus Nuzul Maulana
Published: January 2025

Trichomonas vaginalis is a protozoan parasite responsible for leucorrhoea, transmitted primarily through sexual contact, and commonly affecting the lower urogenital tract. According to the World Health Organization (WHO), the global incidence of trichomoniasis is estimated at 180 million cases annually. In the United States, the infection affects around 2-3 million women annually, with the organism also found in 30-40% of male sexual partners. This study aimed to examine the presence of Trichomonas vaginalis in adolescent urine samples and assess their vaginal hygiene practices in Balongbendo Village, Sidoarjo, East Java, Indonesia. Trichomonas vaginalis is widely prevalent across the globe, including both rural and urban areas. This focused study utilized both experimental and questionnaire-based approaches. Urine samples from 25 adolescents were analyzed directly for Trichomonas vaginalis presence, while a questionnaire was administered to assess personal hygiene practices, particularly focusing on genital care. Data were analyzed using One-Way ANOVA and Chi-Square tests to determine statistical significance and percentage distributions. The study identified Trichomonas vaginalis in 5 out of 25 urine samples, indicating a 20% prevalence among the participants. The majority of respondents demonstrated a solid understanding and practice of vaginal hygiene. The analysis revealed a statistically significant relationship between genital hygiene practices and the presence of Trichomonas vaginalis, with a p-value of 0.001 (p < 0.05). The findings indicate that while Trichomonas vaginalis remains present among adolescents in Balongbendo Village, the majority exhibit good vaginal hygiene practices, highlighting the importance of continuous education on genital care in preventing such infections.
Environmental and health implications of liquid waste from the stone carving industry: Case study in Sedayu Village, Magelang, Central Java, Indonesia
Authors: Sutaryono Sutaryono Sutaryono , Rezyana Budi Syahputri  , Tuti Susilowati  , Teguh Setyadi  , Purwanti  , Sukamsi  , Dhanik Ernawati  , Mohamad Samsudin  , Taufiq Hidayat  , Hastin Dyah Kusumawardani  , Ina Kusrini
Published: January 2025

Sedayu Village in Magelang Regency is a hub for stone carving craftsmanship, generating liquid waste that poses potential environmental contamination and health hazards. This study aims to analyze the quality of liquid waste produced and evaluate environmental health risks. Implementing the composite sampling method, liquid waste samples were taken from industrial outlets and released into the Keranjang River. The analyzed parameters include TSS, pH, BOD, COD, nitrate, chromium, and phenol. Laboratory results revealed concentrations of TSS at 200 mg/L, BOD at 50 mg/L, COD at 100 mg/L, nitrite at 1 mg/L, hexavalent chromium at 0.1 mg/L, and phenol at 0.05 mg/L, all exceeding environmental quality standards. The health risk assessment, conducted using the Environmental Health Risk Assessment (EHRA) method, the RQ values for nitrite (0.039), chromium (0.129), and phenol (0.006) are below 1, indicating low immediate risk, chronic exposure could lead to bioaccumulation and long-term health effects such as methemoglobinemia and carcinogenic risks. Thus, immediate intervention is essential. As a mitigation strategy, the study recommends waste management interventions. The proposed WWTP should include activated carbon filtration to remove heavy metals and advanced oxidation processes for organic pollutants like phenol.
Suplementasi Ekstrak Buah Asam Kandis (Garcinia xanthochymus) dalam Air Minum sebagai Acidifier: Pengaruh terhadap Profil Darah dan Diferensiasi Leukosit Puyuh Jepang (Coturnix coturnix japonica)
Authors: Sakti Tri Yuda , Suharti Sri , Suci Dwi margi
Published: January 2025

Organic acids, including those found in sour mangosteen (Garcinia xanthochymus) fruit extract, have the potential as alternatives to antibiotics. This study aimed to evaluate the effect of sour mangosteen fruit extract (SME) supplementation at different acidity levels (pH 4, pH 3, and pH 2) as an acidifier on the blood profile and leukocyte differentiation of adult female Japanese quails (Coturnix coturnix japonica). A completely randomized design (CRD) was applied with four treatments: a control without SME supplementation (P0) and groups receiving SMFE-supplemented drinking water adjusted to pH 4 (P1), pH 3 (P2), and pH 2 (P3). Each treatment was replicated three times with 11 heads per replicate. The extract was administered twice weekly from 6 to 12 weeks of age. All quails were fed a commercial layer diet containing 20% crude protein, 4% crude fat, 6% crude fiber, 4% calcium, and 0.6% total phosphor. The observed parameters included blood profile indices (erythrocytes, hemoglobin, hematocrit, leukocytes) and leukocyte differentiation (lymphocytes, monocytes, heteropils, and neutrophils). The results indicated that SME supplementation at pH 4, pH 3 and pH 2 in drinking water did not significantly affect the blood profile or leukocyte differentiation. These finding suggest that Garcinia xanthochymus fruit extract at these acidity levels can be effectively utilized as an acidifier in drinking water.
Evaluating LRCN аnd ConvLSTM Models for Nеurоlоgісаl and Muѕсulоѕkеlеtаl Dіѕеаѕе сlаѕѕіfісаtіоn frоm vіdео Data
Authors: Abdali Abdulrazzaq Zainab , Mahdi Chyad Adala
Published: January 2025

An extensive analysis оf Lоng term Short-Term Mеmоrу Convolutional Lоng term Short-Term Mеmоrу (ConvLSTM) аnd Recurring Cоnvоlutіоnаl Networks (LRCN) for classification of dіѕеаѕе аnd рrеdісtіоn of recovery through data captured by vіdео is рrеѕеntеd іn this аrtісlе. Thе mаіn goal іѕ to uѕе deep lеаrnіng architectures tо dіаgnоѕе nеurоlоgісаl аnd muѕсulоѕkеlеtаl іllnеѕѕеѕ, such as stroke, Pаrkіnѕоn'ѕ dіѕеаѕе, orthopedic іѕѕuеѕ, аnd typical gait раttеrnѕ. For bоth LRCN аnd CоnvLSTM models, реrfоrmаnсе measures including exactness, recollection, F1-ѕсоrе, and аrе thoroughly еxаmіnеd in relation tо recovery рrеdісtіоn аnd vіdео сlаѕѕіfісаtіоn correctness tаѕkѕ. LRCN models perform wеll in vіdео саtеgоrіzаtіоn; thеіr accuracy іѕ 0.98 аnd thеіr exactness, rесollection, аnd F1-ѕсоrе mасrо аnd weighted аvеrаgеѕ аrе 0.90. CоnvLSTM mоdеlѕ, оn thе оthеr hand, реrfоrm wоrѕе; thеіr accuracy is 0.96 whіlе their рrесіѕіоn, recall, аnd F1-ѕсоrе mеtrісѕ rаngе frоm 0.94 to 0.96. Thеѕе findings imply that, when іt comes tо uѕіng vіdео dаtа to classify gаіt раttеrnѕ ѕuggеѕtіvе оf nеurоlоgісаl and musculoskeletal dіѕоrdеrѕ, LRCN mоdеlѕ outperform CоnvLSTM mоdеlѕ іn this rеgаrd. ConvLSTM Mоdеl 1 performs better in rесоvеrу prediction, wіth аn accuracy of 0.96 аnd mасrо аvеrаgе exactness, rесollection, аnd F1-score of 0.95, 0.98, аnd 0.98, rеѕресtіvеlу. CоnvLSTM Mоdеl 2, оn thе other hаnd, has ѕubраr реrfоrmаnсе, wіth mеtrісѕ rаngіng frоm 0.57 tо 0.63. Mеtrісѕ fоr LRCN mоdеlѕ ѕhоw that thеу аrе ѕоmеwhаt gооd аt рrеdісtіng rесоvеrу stages; thеу rаngе frоm 0.78 tо 0.85. Furthermore, a Flаѕk аррlісаtіоn іnсоrроrаtіng trained ConvLSTM аnd LRCN mоdеlѕ іѕ constructed fоr ѕmооth vіdео upload аnd рrеdісtіоn. The uѕеr-frіеndlу іntеrfасе of the application enables uѕеrѕ tо upload vіdеоѕ аnd rесеіvе рrеdісtіоnѕ fоr thе classification of diseases аnd the аѕѕеѕѕmеnt of recovery periods.
Random Multimodal Convolutional Forward Taylor Network for Personality Prediction using MBTI Data
Authors: Sabeeha Vian , Bahaaulddin A. Alwahhabb Ahmed
Published: January 2025

The growth of social media for self-awareness and self-expression has raised more attention to the Myers-Briggs Type Indicator (MBTI) for analyzing people's personalities. Nevertheless, additional research is required to determine various word embedding and data handling methods to enhance the accuracy of MBTI personality-type predictions. Therefore, a new technique known as Random Multimodal Convolutional Forward Taylor Network (RMConv FT-Net) is devised to predict personality. Initially, text data from the database is considered input, and then tokenization is performed to split the text into tokens, which is done by Bidirectional Encoder Representations from Transformers (BERT). After this, various features, including linguistic features and several other features, like Term Frequency-Inverse Document Frequency (TF-IDF), Word2Vec, and so on, are mined from the text. Following this, the data imbalance problem is addressed by employing oversampling. Finally, personality prediction is performed by utilizing RMConv FT-Net, designed with the incorporation of the Convolutional Neural Network (CNN), Taylor series, and Random Multimodal Deep Learning (RMDL). The experimental outcomes of RMConv FT-Net based on Mean Square Error (MSE), Mean Absolute Percentage Error (MAPE), and Root Mean Square Error (RMSE) show that it obtained the values of 0.017, 0.047, and 0.129.
Breast Cancer Detection and Diagnosis Using Gabor Features and EfficientNetV2 Model
Authors: Ali Dihin Rasha
Published: January 2025

Breast cancer is one of the most common diseases and the second most dangerous and fatal disease after skin cancer. The malignant masses begin to grow in the breast cells and develop in the breast tissue of women all over the world. Due to the necessity of early diagnosis to prevent the development of cancer and thus improve the chances of survival, many computer-aided methods are available to automate tissue classification to reduce the workload of the pathologist and improve accuracy. In this paper, a proposed method Gabor-EfficientNetV2 to extract deep features from a breast cancer dataset called “Breast cancer Histopathological dataset” (BreaKHis) to classify it as “benign” or “malignant” based on Gabor filter bank and EfficientNetV2 architecture. The proposed Gabor-EfficientNetV2 model offers significant advances in breast cancer detection and diagnosis by combining the texture analysis capabilities of Gabor filters with the efficiency and scalability of the EfficientNetV2 architecture. This hybrid approach enhances feature representation, resulting in improved classification accuracy and robustness compared to traditional models. Highest classification accuracy obtained with 400X magnification factor where the train accuracy of 97% and train loss of 0.13% while the test accuracy of 96.3% and the test loss of 0.135%, precision of 97.30% ,  recall of  90.30% , and F1-score obtained is 98.52%.
Develop Whale Optimization Algorithm(WOA) In Genetic Method To Predict the Optimal Treatment for Diseases
Authors: Adil Madlool Zuhal
Published: January 2025

Recently, a greater emphasis in research is on the targeting the parameters responsible for the spread of diseases, particularly in managing the complexities of large datasets related to disease information One of the major problems is trying to attain a high level of precision because some data sets in big data can be incomplete. The scope of this research involves advanced learning systems to formulate a system which provides best course of action against treatment recommends of any disease. Among other approaches, dealing with the missing data points and regularization of disease databases are included. The Whale Optimization Algorithm (WOA) will be developed to enhance predictions of effective treatments for diseases, utilizing genetic algorithms, which have unique features that set them apart from other methods. The results of the proposed approach showed significant improvement in predicting the appropriate treatment for diseases, compared to earlier results obtained with the WOA algorithm before its enhancement. The new method demonstrated higher accuracy reaching 98%.
Improvement in the Decay Resistance of Melia Dubia Wood against White Rot Fungi and Changes in Properties due to Thermo-Hydro-Mechanical Modification
Authors:   forest research institute,dehradun,uttarakhand,248006
Published: January 2025

Despite extensive studies on thermal modification, limited research
has focused on fast-growing, short-rotation species like Melia dubia. While
Melia dubia holds significant industrial importance due to its rapid growth
and high demand in the pulpwood, plywood, and timber sectors, the juvenile
wood produced in short-rotation plantations is often less durable. Thermo
hydro mechanical (THM) modification combines thermal and mechanical
treatment under controlled conditions, offers a sustainable, eco-friendly
alternative to chemical preservative treatments. In the current study,
specimens from Melia dubia wood were used to obtain wood material with
improved decay resistance by using THM treatment, performed at four
temperatures: 160°C, 170°C, 180°C, and 190°C. Fungal resistance was
tested under laboratory conditions through a soil block bioassay against
white rot fungi Trametes versicolor, which indicated that decay resistance
increased with increasing temperature. The highest weight loss was
recorded in the untreated control samples, whereas the samples treated
at 190°C showed the lowest weight loss percentage, indicating enhanced
decay resistance. At the same time, noticeable changes in color, weight
loss, and thickness were observed post-treatment. Correlation analysis
derived from a scatterplot matrix revealed a positive correlation between
temperature and density (r = 0.51), a significant negative correlation
between temperature and weight (r = -0.45), and a weak, non-significant
negative trend between weight and density (r = -0.14). These findings
highlight that higher temperatures increase density while reducing weight
and thickness, improving wood durability.
A ATELECTASIA PULMONAR E SUA ATUAÇÃO EM ALGUMAS PATOLOGIAS RESPIRATÓRIAS
Authors: Souza Vitória De Oliveira , Sganzella Daiana , Fernandes Raíssa Araújo Porto , Soares Amandha Pimenta , Nunes Victória Kamilly Fortunato de Sousa , Braga Lyvia Rodrigues Parreira
Published: January 2025

Introdução - A atelectasia pulmonar afeta a expansão total ou parcial do pulmão, decorrente do mau funcionamento dos alvéolos, em razão da obstrução brônquica, pressão local no parênquima pulmonar, dé
OS IMPACTOS PSICOLÓGICOS DO PRECONCEITO INTRAFAMILIAR CONTRA FILHOS HOMOSSEXUAIS
Authors: Sousa Thayla Julia dos Santos , Aragão Danubya Oliveira Pires
Published: January 2025

Os impactos psicológicos decorrentes do preconceito intrafamiliar é um tema pouco investigado na literatura científica. Dessa forma, o presente estudo teve por objetivo apresentar uma revisão integrativa da literatura científica expondo os marcos do preconceito na sociedade, além de visar a uma maior compreensão das repercussões da revelação da orientação sexual nas relações familiares, as consequências da não aceitação dos pais e o modo como a rede de apoio auxilia no enfretamento do preconceito. A partir das bases: Periódico Eletrônicos em Psicologia (Pepsic), Scientific Electronic Library Online (Scielo), Literatura Latino-Americana e do Caribe em Ciências da Saúde (Lilacs), Index psicologia- periódicos de 2019 a 2024. As análises apresentadas reafirmaram que a sociedade se constitui como fator que influencia o modo de pensar das pessoas que compõe a família, sendo a falta de diálogo uma das percussoras para manutenção desse tabu. Acredita-se, então que a difusão da homofobia familiar consolida o simbolismo do homossexual como um ser menos humano.

Palavras-chave: Homossexuais. Homofobia. Preconceito Familiar. Violência. Impactos Psicológicos.
PACIENTES HOSPITALIZADOS NUMA UNIDADE DE TERAPIA INTENSIVA NO PARANÁ, BRASIL: ESTUDO TRANSVERSAL ANINHADO À COORTE
Authors: Ciccheto Julia Rosa Matias , Fogaça Rabito Lucas Benedito , Mendonça Brandão Mônica , Hirata Leite Wellington Kenji , Passos Matos Endric , Nogueira Sanches Rafaely de Cassia
Published: January 2025

Objetivo: Describir las características clínico-epidemiológicas de pacientes hospitalizados en una unidad de cuidados intensivos (UCI) en Brasil durante un período de 12 meses. Material y Método: Estudio transversal, prospectivo, anidado dentro de una cohorte, realizado en la unidad de cuidados intensivos de adultos de un hospital universitario. Para la recolección de datos, se utilizaron datos de la historia clínica electrónica a través del Sistema de Gestión de la Atención en Salud del Sistema Único de Salud para el seguimiento de los ingresos y los resultados de los pacientes hospitalizados en el período definido. Se obtuvieron datos de variables como sexo, raza-color, grupo etario, municipio de residencia, sector de procedencia, necesidad de cirugía, uso de fármacos vasoactivos, presencia de infecciones agudas, presencia de determinadas comorbilidades, hábitos de vida, deterioro del sistema y evolución clínica. Los datos fueron sometidos a análisis mediante estadística descriptiva simple utilizando el software R. Resultados: De los 252 pacientes, la mayoría eran del sexo masculino (59,13%) y sus edades oscilaban entre 18 y 94 años (?=58,6), siendo 134 de ellos mayores de 60 años. La mayoría eran de raza blanca (62,70%) y la mayoría de las internaciones fueron de pacientes residentes en municipios próximos a la ciudad de Maringá (52,38%), 96 pacientes negaron realizar alguna práctica perjudicial para la salud. El motivo de internación o el sistema del cuerpo humano más afectado por la internación en la UCI fue el sistema pulmonar (22,22%). Conclusión: La mayor prevalencia de ingresos a la unidad de cuidados intensivos se debió a individuos del sexo masculino, con edades entre 41 y 59 años, provenientes de urgencias, que requirieron cirugía, tener comorbilidades, ser fumadores y tener alta domiciliaria.
VALIDEZ DE CONTENIDOS PARA UN EXAMEN DE TITULACIÓN EN ENFERMERÍA
Authors: Barrios Araya Silvia Cristina , Urrutia Egaña Marcela Javiera , Guerra Ferrada Carolina
Published: January 2025

Objetivo: Evaluar la estructura y validez de contenido del banco de “Multiple Choice Questions” (MCQ) del examen de titulación de una carrera de enfermería de una institución de la región metropolitana de Chile, según tipos de conocimiento y las habilidades cognitivas. Material y Método: Estudio metodológico cuantitativo, con una muestra de 1.108 MCQ retenidas entre el 2017 a diciembre 2020; las variables fueron: complejidad de los contenidos y las habilidades cognitivas; para categorizar los MCQ se utilizó la clasificación de ítems propuesta por Barrios, Urrutia y Catoni; se conformó un panel de jueces expertos con 26 profesores, previo consentimiento informado; cada profesor analizó en promedio 43 ítems y emitió juicio respecto a: a) pertinencia del MCQ en el examen de titulación, b) dificultad para evaluarlo y c) tipo de conocimiento y habilidad cognitiva a evaluar. Los ítems dudosos se resolvieron con entrevista cognitiva, grabada y autorizada, a egresados y transcrita verbatim. Resultados: el 50,9% de los MCQ se clasificaron como relevantes para incorporarse al examen de titulación. De los 564 MCQ pertinentes, el 75% evalúa un conocimiento de tipo conceptual y el 17% procedimental; con relación a la habilidad cognitiva, el 46,5% evalúa habilidades superiores. Al analizar la correspondencia existente entre los MCQ con las competencias declaradas en el perfil de egreso, 404 del total de MCQ contribuyen a las competencias asistenciales, 78 a gestión, 50 a investigación, 20 a educación y 12 a competencias transversales. Conclusión: Esta evaluación contribuyó a asegurar la construcción de un examen de titulación que cumple con los criterios de validez de contenido y psicométrico.
PATRONES DE CONDUCTAS OBSERVADAS EN MADRES DE RECIÉN NACIDOS EN SITUACIÓN DE STRESS
Authors: Barraza Peña Carmen Gloria , Sepulveda Guerra Elena
Published: January 2025

Objetivo: Determinar si los reactivos observados en la Escala de Indicadores de Apego madre-hijo en condiciones de stress (Attachment During Stress, ADS), corresponden a los patrones de conducta observados en las grabaciones de las díadas madre-hijo, por saturación de la muestra, durante el contacto piel a piel en los horarios de visita de recién nacidos, en una unidad de neonatología de un hospital público de la Región del Biobío, Chile. Material y Método: Estudio descriptivo, realizado el primer semestre 2019, basado en la observación de 21 díadas madre-hijo, durante el período de visitas a sus hijos hospitalizados en la unidad neonatal, previo consentimiento y orientación de la aplicación del contacto piel a piel. Se realizaron 15 sesiones de 40 min de grabación en audio-video las cuales fueron transcritas, clasificando los patrones de conducta y su relación con las dimensiones que expresa la escala. Resultados: Las dimensiones establecidas en la escala ADS se relacionan con los patrones de conductas observadas en el contacto piel a piel de la díada, donde el ítem “Mirada”, fue el que obtuvo mayor porcentaje. Conclusión: Un tamizaje precoz en la relación de la díada, permite evaluar el tipo de apego, facilitando intervenciones interprofesionales oportunas en pro de la relación vincular, la escala Indicadores de Apego madre-hijo en condiciones de stress es útil, pertinente, de fácil aplicación y acceso.
DESENVOLVIMENTO DE WEBSITE INFORMATIVO PARA MANEJO DA PESSOA COM AGITAÇÃO PSICOMOTORA: ESTUDO DE VALIDAÇÃO
Authors: Menon Pelissoni Amanda , Yamawaka de Almeida Letícia , de Campos Tibúrcio Priscila , de Melo Filho Pedro Leite , Coronato Fernandes Mariana , de Sousa Nóbrega Maria do Perpétuo Socorro
Published: January 2025

Objetivo: Describir el desarrollo y evaluación de un sitio web informativo para el manejo de personas con agitación psicomotora con o sin conductas agresivas. Material y Método: Estudio metodológico del desarrollo de tecnología en salud, que abarcó las etapas: revisión de literatura, desarrollo de tecnología y evaluación de contenido propuesto por Clement Mok. La preparación implicó el uso de Microsoft Office Word, Adobe Photoshop CC, Lenguaje de marcado de hipertexto, Cascading Style Sheets, Safari y el software Google Chrome. Para llegar a un acuerdo se adoptó un Índice de Validación de Contenido (CVI) mínimo de 0,78. La primera ronda de validación se realizó entre agosto y octubre de 2021 y la segunda entre enero y febrero de 2022, ambas con la participación de 10 expertos. Resultados: La estructura y el contenido del sitio web ilustran la descripción del concepto de agitación, agresión y violencia, prácticas de manejo ambiental y conductual, condiciones de salud, condiciones/predictores de agitación psicomotora y riesgos de empeoramiento, además del video de aprendizaje electrónico estructurado en tres escenas que simulan un inadecuado y adecuado manejo y síntesis de contenidos. De las 28 preguntas evaluadas, 27 presentaron valores superiores a 0,800. En cuanto a la validación de contenido, el alfa de Cronbach fue de 0,979% y el valor medio del Índice de Validación de Contenido final fue de 0,900. Conclusión: El sitio web presentó indicios de validez adecuada, lo que sugiere que tiene potencial para ser agregado a espacios de atención, formación y capacitación.
Design, optimization and in vitro characterization of valsartan loaded floating tablets
Authors: Soujanya  , Anand Kumar Y  , Yashashwini B
Published: January 2025

The present work was aim to design and optimize floating drug delivery systems of Valsartan using HPMC K15M, HPMC K100M, Guar gum as polymer and sodium bicarbonate as a gas generating agent. The tablets were prepared by direct compression method. Response surface methodology (RSM) was adapted using Box Behnken Design (BBD) using amount of HPMC K15M (X1), HPMC K100M (X2) and Guar gum (X3) were selected as independent variables, buoyancy time (Y1) and t50 (Y2) selected as dependent variables. All the designed 15 trial batches of formulations were evaluated for precompression, postcompression, drug content uniformity, swelling index, in vitro buoyancy, floating period and in vitro drug release profile. The response data were analyzed by using Design Expert software trial V13 to study the influence of independent variables on dependent variables. Point prediction method was adapted to generate optimized formulation with predicted response values within the design space. Validity of the developed polynomial equation was verified by experimenting the optimized formula. The closeness of predicted and observed values for buoyancy time (Y1) and t50 (Y2) indicates validity of derived equations for the dependent variables. These studies indicated that the proper balance between HPMC K15M (X1), HPMC K100M (X2) and Guar gum (X3) can produce a desired buoyancy and predicted dissolution profile. The optimized formulations followed Korsemeyer peppas kinetics while the drug release mechanism was found to be anomalous type, controlled by diffusion through the swollen matrix.