bluuebunny/crossref_metadata_2025 huggingface dataset:
Catechol-O-Methyltransferase Val158Met
Polymorphism is Associated with Pain and
Disability, but not Widespread Pressure Pain
Sensitivity, in Women with Carpal Tunnel Syndrome
Authors: Fernández-de-las-Peñas César
Published: March 2021

Background: The genetic influence of Val158Met polymorphisms, one of the potential genetic
determinants for nociceptive processing, has not been previously investigated in women with carpal
tunnel syndrome (CTS).
Objectives: To investigate the association between the Val158Met polymorphism with CTS and
to assess the relationship between the Val158Met polymorphism and the clinical outcomes and
widespread pressure pain hypersensitivity in women with CTS.
Study Design: Case control study.
Setting: Neurology department at an urban hospital.
Method: One hundred nine (n = 109) women (mean age: 47 ± 9 years) with a clinical and
electrodiagnostic diagnosis of CTS and 109 matched healthy women participated. After amplifying
the Val158Met polymorphism by polymerase chain reactions, rs4680 genotype frequencies and allele
distributions were calculated. We classified individuals according to their Val158Met polymorphism:
Val/Val, Val/Met, Met/Met. The intensity of the pain was assessed with a numeric rating scale (0-10)
and disability was determined with the Boston Carpal Tunnel Questionnaire. Pressure pain thresholds
were bilaterally assessed over median, radial, and ulnar nerve trunks; C5-C6 facet joints; and carpal
tunnel and tibialis anterior muscles.
Institutional Review Board: The study project was approved by the local human research committee
(HUFA-12/14). All participants signed an informed consent prior to their inclusion in the study.
Results: The distribution of the 3 Val158Met genotypes (Val/Val, Val/Met, Met/Met) and alleles
was not significantly different between women with CTS and healthy women (χ2 = 0.498; P =
0.780). Women with CTS carrying the Met/Met genotype showed higher levels of pain and disability
than those with the Val/Met genotype (P < 0.01) and with the Val/Val genotype (P < 0.001). No
differences in the years with pain (P = 0.954), age (P = 0.740), depression (P = 0.530), severity of
CTS (P = 0.744) or presence of unilateral-bilateral symptoms (P = 0.279) existed depending on the
rs4680 Val158Met genotype. No significant differences in widespread pressure pain sensitivity were
observed in any of the points depending on the rs4680 Val158Met genotype (P > 0.315).
Limitations: We only recruited women from a specialized department.
Conclusion: Current results indicated that the Val158Met polymorphism seems not to be a risk
factor for the development of CTS; however, it was associated with increased perception of pain
and higher disability scores.
Key words: Catechol-O-methyltransferase gene, carpal tunnel syndrome, polymorphism pressure
pain thresholds, sensitivity.
An Update of the Systematic Appraisal of the
Accuracy and Utility of Lumbar Discography in
Chronic Low Back Pain
Authors: Manchikanti Laxmaiah
Published: March 2021

Background: The intervertebral disc has been implicated as a major cause of chronic lumbar
spinal pain based on clinical, basic science, and epidemiological research. There is, however, a
lack of consensus regarding the diagnosis and treatment of intervertebral disc disorders. Based on
controlled evaluations, lumbar intervertebral discs have been shown to be the source of chronic
back pain without disc herniation in 26% to 39% of patients. Lumbar provocation discography,
which includes disc stimulation and morphological evaluation, is often used to distinguish a
painful disc from other potential sources of pain. Despite the extensive literature, intense debate
continues about lumbar discography as a diagnostic tool.
Study Design: A systematic review of the diagnostic accuracy of lumbar provocation and
analgesic discography literature.
Objective: To systematically assess and re-evaluate the diagnostic accuracy of lumbar discography.
Methods: The available literature on lumbar discography was reviewed. A methodological quality
assessment of included studies was performed using the Quality Appraisal of Reliability Studies
(QAREL) checklist. Only diagnostic accuracy studies meeting at least 50% of the designated
inclusion criteria were included in the analysis. However, studies scoring less than 50% are
presented descriptively and critically analyzed.
The level of evidence was classified as good, fair, and limited or poor based on the quality of
evidence developed by the U.S. Preventive Services Task Force (USPSTF).
Data sources included relevant literature identified through searches of PubMed and EMBASE
from 1966 to September 2012, and manual searches of the bibliographies of known primary and
review articles.
Results: Over 160 studies were considered for inclusion. Of these, 33 studies compared discography
with other diagnostic tests, 30 studies assessed the diagnostic accuracy of discography, 22 studies
assessed surgical outcomes for discogenic pain, and 3 studies assessed the prevalence of lumbar
discogenic pain. The quality of the overall evidence supporting provocation discography based on
the above studies appears to be fair. The prevalence of internal disc disruption is estimated to be
39% to 42%, whereas the prevalence of discogenic pain without assessing internal disc disruption
is 26%.
Conclusion: This systematic review illustrates that lumbar provocation discography performed
according to the International Association for the Study of Pain (IASP) criteria may be a useful tool
for evaluating chronic lumbar discogenic pain.
Key words: Lumbar intervertebral disc, lumbar discography, provocation discography, analgesic
discography, diagnostic accuracy
Memory-Dependent Forecasting of COVID-19: The Flexibility of Extrapolated Kernel Least Mean Square Algorithm
Authors: Ahmad Noor , Mohd Mohd Hafiz
Published: March 2021

The extrapolated kernel least mean square algorithm (extrap-KLMS) with memory is proposed for the forecasting of future trends of COVID-19. The extrap-KLMS is derived in the framework of data-driven modelling that attempts to describe the dynamics of infectious disease by reconstructing the phase-space of the state variables in a reproducing kernel Hilbert space (RKHS). Short-time forecasting is enabled via an extrapolation of the KLMS trained model using a forward euler step, along the direction of a memory-dependent gradient estimate. A user-defined memory averaging window allows users to incorporate prior knowledge of the history of the pandemic into the gradient estimate thus providing a spectrum of scenario-based estimates of futures trends. The performance of the extrap-KLMS method is validated using data set for Malaysia, Saudi Arabia and Italy in which we highlight the flexibility of the method in capturing persistent trends of the pandemic. A situational analysis of the Malaysian third wave further demonstrate the capabilities of our method
A Dynamic Flow 3-D Solar Energy Cell and Process
Authors: Bushong James
Published: March 2021

This paper proposed a 4-dimensional approach to solar photovoltaic energy, featuring a 3-D porous metal cell with a continuous flow of photovoltaic fluids (e.g. Colloidal Quantum Dots or perovskites) traversing throughout. Rationale and proposed governing equations indicate that significantly more power per unit 2-D panel area could be achieved, offering a method of de facto overcoming power limitations such as Shockley-Queisser and recombination in conventional 2-D passive solar panels. The main goal is to initiate thought and collaboration with experts in electrical engineering, physics, colloidal quantum dots, perovskites, capacitors/batteries, and any other related field that could help this approach become a commercial reality. Potential applications include those where maximum solar power is desired yet space is limited- such as an on-board solar panel for electric vehicles.
Covid-19 detection via deep neural network and occlusion sensitivity maps
Authors: Ahmad Noor , Aminu Muhammad , Noor Mohd Halim Mohd
Published: March 2021

Deep learning approaches have attracted a lot of attention in the automatic detection of Covid-19 and transfer learning is the most common approach. However, majority of the pre-trained models are trained on color images, which can cause inefficiencies when fine-tuning the models on Covid-19 images which are often grayscale. To address this issue, we propose a deep learning architecture called CovidNet which requires a relatively smaller number of parameters. CovidNet accepts grayscale images as inputs and is suitable for training with limited training dataset. Experimental results show that CovidNet outperforms other state-of-the-art deep learning models for Covid-19 detection.
Chemistry, Cyclophosphamide, Cancer Chemotherapy, and Serendipity: Sixty Years On
Authors: Zon Gerald
Published: March 2021

Cambridge Dictionary: serendipity | noun | the phenomenon of finding interesting or valuable things by chance.

The year 2019 marked the 60th anniversary of the approval of cyclophosphamide (CP) as an anticancer by the U.S. Food & Drug Administration in 1959 for the treatment of lymphoma. Between 1959 and 2019 there were ~50,000 publications listed in PubMed that have CP in the title and/or abstract, with these annual numbers showing a continual increase, and over 1,800 such articles in 2019 alone. The discovery of CP is a prime example of serendipity in science, which also applies to key elements of the metabolism and pharmacological basis for the specificity of the cytotoxicity of CP toward cancer cells. Phosphoramide mustard (PM), HO(H2N)P(O)N(CH2CH2Cl)2, the principal metabolite of CP with DNA alkylating activity, was synthesized and reported by Friedman and Seligman in 1954 prior to the discovery of CP. Interestingly, the original drug design premise for synthesizing PM, which was based on elevated phosphamidase enzyme activity in cancer cells proved to be incorrect. While this wrong premise also led to the synthesis of CP, as a six-membered ring cyclic phosphamidase-activated precursor of PM, the actual metabolic conversion of CP to PM was subsequently found to involve a surprisingly complex array of metabolites and metabolic pathways, all completely unrelated to phosphamidase. Although the molecular structure of CP has an asymmetrically substituted, i.e. chiral phosphorus center, the racemic mixture of the Rp and Sp enantiomers of CP was used throughout its initial investigations and subsequent clinical trials despite the involvement of an initial enzyme-mediated metabolic activation step, which could, in principle, be stereoselective for only one of the enantiomers of CP. Stereochemical investigations along those lines were eventually carried out, but the results did not warrant replacement of racemic CP with either enantiomer in the clinic. Amazingly, there are now ~4,000 structural congeners of PM listed Chemical Abstracts, but none have led to an anticancer drug superior to CP. This account provides a synopsis of the key chemistry and stereochemistry investigations that comprise this story of CP, as a remarkable instance of serendipity in science, and my chance involvement in the unfolding of this fascinating story.
ARAÇ İÇİ SESİNDEN ARACI TANIMA VE SINIFLANDIRMA
Authors: AYDEMİR Emrah , IŞIK Murat
Published: March 2021

Günümüzde, teknolojik imkanların hızla gelişmesiyle ses sınıflandırma uygulamalarının sayıları da artmakta ve popüler bir çalışma alanı haline gelmektedir. Bu çalışmada, amacımız durağan halde bir aracın üretmiş olduğu sesi kullanarak "aracın sesli imzasını" üretmek ve aracın sınıflandırılması için kullanmaktır. Çalışan bir aracın sesi; motor sesi, titreşimden kaynaklı sesler, rüzgâr sesleri gibi bazı seslerin bir araya gelmesiyle oluşur. Uygulamada 22 aracın rölantideki sesleri kaydedilmiş ve Local Binary Pattern (LBP) ve Cubic SVM algoritmaları kullanılarak %95,2 oranında başarılı sınıflandırılmıştır. Ayrıca, elde edilen sonuçlar literatürdeki çalışmalarla karşılaştırılmıştır.
Benarkah Self Compassion dapat Mengurangi Gejala Body Dysmorphic Disorder?
Authors: Rinaldi Martaria Rizky , Fatmala Dea Nada
Published: March 2021

Penelitian ini bertujuan untuk mengetahui hubungan antara self compassion dengan gejala body dysmorphic disorder pada remaja putri. Hipotesis yang diajukan dalam penelitian ini adalah ada hubungan negatif antara self compassion dengan gejala body dysmorphic disorder. Subjek dalam penelitian ini ber jumlah 105 orang. Pengambilan subjek menggunakan purposive sampling, data dikumpulkan menggunakan skala Self Compassion dan skala Gejala Body Dysmorphic Disorder. Analisis data penelitian ini menggunakan korelasi product moment dari Pearson. Berdasarkan hasil analisis, diperoleh koefisien korelasi (rxy) = -0,336 (p<0,005). Hasil tersebut menunjukkan bahwa terdapat hubungan negatif yang signifikan antara self compassion dengan gejala body dsymorphic disorder. Artinya semakin tinggi self compassion yang dilakukan individu maka semakin rendah gejala body dysmophic disorder yang dimilikinya, sebaliknya semakin rendah self compassion maka semakin rendah gejala body dysmorphic disorderyang dimiliki individu. Koefisien determinasi (R2) yaitu 0,113 yang menunjukkan sumbangan efektif 11,3% dari self compassion untuk gejala body dysmorphic disorder.
Kepemilikan Institusional dan Transparansi Informasi terhadap Penghindaran Pajak: Sebelum, Saat, dan Setelah Tax Amnesty
Authors: Razali Razali , Ferawati Ferawati
Published: March 2021

This study aims to analyze the effect of institutional ownership and transparency of information on tax avoidance before, during, and after tax amnesty. This study uses secondary data obtained from the company’s financial statement of companies listed in Indeks of LQ-45 from 2015-2017 represented timeline of tax amnesty. The data analysis method used in this research is multiple linear regression analysis. Data collected will be processed by using SPSS. The result of this study shows that institutional ownership and transparency of information has no effect on tax avoidance. The highest tax avoidance ratio occured in 2016, when tax amnesty was conducted.
Pengaruh Struktur Kepemilikan Terhadap Manajemen Laba dan Dampaknya Terhadap Nilai Perusahaan
Authors: Yusnita Rita Tri
Published: March 2021

This study aims to determine the effect of simultaneous and partial ownership structure and earnings management on firm value in the Consumer Goods Industry Sector Companies that are listed on the Indonesia Stock Exchange in 2014. The method used in this study is the census method. The population studied was 32 companies in the Consumer Goods Industry Sector that were listed on the Indonesia Stock Exchange in 2014. The data collected were secondary data. Analysis of the data in this study used path analysis using SPSS V. 24. The results showed that the ownership structure and earnings management, simultaneously, had a significant effect on the value of the company in the Consumer Goods Industry Sector Companies that were listed on the Indonesia Stock Exchange in 2014. The ownership structure, partially, has no significant effect on the value of the company in the Consumer Goods Industry Sector Companies listed on the Indonesia Stock Exchange in 2014. Earnings management, partially, has a significant effect on the firm value of the Consumer Goods Industry Sector Companies that are listed on the Exchange Indonesian Securities in 2014, and ownership structure does not significantly influence earnings management in the Consumer Goods Industry Sector Companies that are listed on the Indonesia Stock Exchange in 2014. Keywords: ownership structure, earnings management, company value
PENGARUH PERPUTARAN KAS DAN PERPUTARAN PERSEDIAAN TERHADAP PROFITABILITAS PERUSAHAAN
Authors: Judin Afifah Septiani , Somantri Yeni Fitriani , Rahayu Intan
Published: March 2021

ABSTRACT.The purpose of this research is to know the description of cash turnover, inventory turnover and profitability in cosmetic subsector companies and household needs listed on the Indonesia Stock Exchange for period 2014 to 2019. This study uses quatitative research methods with an assosiative descriptive approach with a causal form of relation-ship. This research uses nonprobability sampling techniques with secondary data types and collection techniques in form of literature research. The data analysis design is used classic assumption test, multiple regression analyses. Based on the result of the study, it is known that the variabel cash turnover partially affects profitability. Partial inventory turnover variables have no effect on profitability, and simultaneously cash turnover and inventory turn-over have a significant impact on profitability. Improving profitability at the company can be done in a variety of ways, including by means, the company can manage its cash turnover as best it can and manage its inventory turnover as wisely as possible. Thus if the company can manage its cash and inventory as best as possible, then the company can get high profitability.Keywords: Cash Turnover, Inventory Turnover and ProfitabilityABSTRAK.Penelitian ini bertujuan untuk menggambarkan perputaran kas, perputaran persediaan terhadap profitabilitas pada perusahaan subsektor kosmetik dan keperluan rumah tangga yang terdaftar di Bursa Efek Indonesia periode tahun 2014 sampai dengan tahun 2019. Penelitian ini menggunakan metode penelitian kuantitatif dengan pendekatan deskriptif asosiatif dengan bentuk hubungan kausal. Penelitian ini menggunakan teknik sampling Nonprobability Sampling dengan jenis data bersifat sekunder dan teknik pengumpulannya berupa penelitian kepustakaan. Rancangan analisis data yang digunakan menggunakan uji asumsi klasik, analisis regresi berganda. Berdasarkan hasil penelitian, diketahui bahwa variabel perputaran kas secara parsial berpengaruh signifikan terhadap profitabilitas. Variabel perputaran persediaan secara parsial tidak berpengaruh terhadap profitabilitas, dan secara simultan perputaran kas dan perputaran persediaan berpengaruh signifikan terhadap profitabilitas. Meningkatkan profitabilitas pada perusahaan bisa dilakukan dengan berbagai cara, diantaranya dengan cara perusahaan dapat mengelola perputaran kas nya dengan sebaik mungkin dan mengelola perputaran persediannya nya dengan sebijak mungkin. Dengan demikian jika perusahaan dapat melakukan pengelolaan kas dan persediaannya dengan sebaik mungkin, maka perusahaan bisa mendapatkan profitabilitas yang tinggi.Kata kunci: Perputaran Kas, Perputaran Persediaan, Profitabilitas
Dampak Pandemi COVID-19 terhadap Perekonomian Dunia
Authors: Arianto Bambang
Published: March 2021

ABSTRAKArtikel ini bertujuan mengelaborasi dampak pandemi virus Corona 19 (Covid-19) terhadap perekonomian dunia. Dikarenakan pandemi Covid 19 telah mempengaruhi stabilitas perekonomian dunia menjadi stagnan dan negatif. International Moneter Fund menyatakan bahwa pandemi Covid 19 telah menyebabkan terjadinya resesi dunia yang ditandai dengan peningkatan angka pengangguran dan kemiskinan setiap negara di dunia. Sedangkan pemulihan ekonomi dengan memperkuat stimulus ekonomi melalui strategi lokal menjadi salah satu alternatif mengembalikan pelembagaan ekonomi di setiap negara. Penelitian ini menggunakan pendekatan studi kepustakaan dengan merujuk berbagai literatur sebagai data pendukung. Artikel ini berpendapat bahwa dampak pandemi Covid-19 telah memberikan banyak dampak negatif bagi perekonomian dunia yang menyebabkan terjadinya resesi ekonomi dunia. Artikel ini juga berpendapat bahwa setiap negara wajib memperkuat stimulus ekonomi untuk menjaga stabilitas ekonomi bangsa. Kata Kunci : Ekonomi dunia, Stimulus Ekonomi, Covid-19. ABSTRACT This article aims to elaborate on the impact of the Corona 19 (Covid-19) virus pandemic on the world economy. Because the Covid 19 pandemic has affected the stability of the world economy to become stagnant and negative. The International Monetary Fund stated that the Covid 19 pandemic had caused a world recession marked by an increase in unemployment and poverty in every country in the world. Meanwhile, economic recovery by strengthening economic stimuli through local strategies is an alternative to restore economic institutionalization in each country. This study uses a literature study approach by referring to various literatures as supporting data. This article argues that the impact of the Covid-19 pandemic has had many negative impacts on the world economy which led to a world economic recession. This article also argues that every country is obliged to strengthen economic stimulus to maintain the stability of the nation's economy.Keywords : World economy, Economic Stimulus, Covid-19.
Fatores que interferem na realização do aleitamento materno exclusivo
Authors: De Oliveira Rios Pereira Andressa , De Menezes Ferreira Raquel , Marcelino de Rezende e Silva Fernanda , Amaral Nogueira Quadros Karla , Consolação dos Santos Regina , Nunes Andrade Silmara
Published: March 2021

Objetivo: compreender a importância do aleitamento materno exclusivo (AME) e identificar os fatores que dificultam esse processo. Método: trata-se de uma revisão sistemática. As bases de dados consultadas foram a Literatura Latino-Americana e do Caribe em Ciências de Saúde, a Base de Dados Bibliográficos Especializada na írea de Enfermagem, a Medical Literature Analysis and Retrieval System Online e a Scientific Electronic Library Online. Resultados: a pesquisa resultou em 28 artigos, dos quais 11 atendiam a este estudo. A maioria dos fatores encontrados nos resultados (5) apresentou como fator de risco o uso de mamadeiras, a alimentação complementar e as chupetas; seguidos do grau de escolaridade das mães e de fatores socioeconômicos (4); do estado emocional das mães, do tipo de parto, de mães que trabalham fora e da falta de preparo dos profissionais (3). Outros fatores apareceram em menor ocorrência. Conclusão: o êxito do AME se faz com uma abordagem holí­stica e efetiva dos profissionais de Enfermagem em todas as etapas da gestação: a concepção, o pré-natal e o puerpério.
Fatores relacionados ao manejo clí­nico e educacional do paciente em perí­odo pré e pós-transplante cardí­aco: revisão integrativa
Authors: Alves de Souza Gleicilaine , Cordeiro Gonçalves Karla , De Fátima Silqueira Salete Maria
Published: March 2021

Objetivo: Analisar as recomendações de condutas terapêuticas e educacionais na assistência ao paciente em perí­odo pré e pós-transplante cardí­aco. Métodos: Trata-se de revisão integrativa baseada na estratégia PICO, realizada com 12 artigos gerados através de pesquisa nas bases de dados LILACS; MEDLINE; BDENF; IBECS; BINACIS e COLECIONASUS em agosto de 2019. Resultados: É recomendado a atuação da equipe multidisciplinar especializada em transplante e a educação em saúde. Maior grau de instrução, melhor condição cognitiva e altos ní­veis de satisfação social são preditivos de aumento nos anos de sobrevida pós-transplante. Os principais aspectos a serem trabalhados são: ação da insuficiência cardí­aca e seu impacto no organismo, tratamentos disponí­veis, perí­odo de recuperação, rotinas de exames e acompanhamento. Conclusão: Diante da complexidade do tema faz-se necessário uma equipe assistencial especializada e a reflexão sobre a inclusão do cardiopata e familiares no processo. O apoio psicológico gera melhores resultados e adesão ao tratamento.
Cuidado dentro de casa: reflexões sobre visitas domiciliares na Estratégia Saúde da Famí­lia
Authors: Borges de Assis Lana Muriely , De Lima Pinheiro Marina , Medeiros de Morais Melissa Maria , Mota Araripe Pereira Fernandes Denise , Costa de Melo Vilma Felipe , Falcão Motta Mariana
Published: March 2021

A Visita Domiciliar (VD) é uma prática do leque de cuidados ofertados pela Atenção Primária í  Saúde que visa prestar assistência na moradia das pessoas. Objetivo: Dialogar sobre a relevância da VD, abordando a imersão em laços criados com as pessoas no seio de suas casas. Métodos: Trata-se de um relato de experiência realizado por residentes de Medicina de Famí­lia e Comunidade (MFC) de uma equipe de Estratégia de Saúde da Famí­lia, na cidade de João Pessoa (PB). Resultados: Através das VD, pôde-se entender a dinâmica das famí­lias, permitindo realizar o cuidado de maneira equânime e integral, principalmente diante da pandemia pelo COVID-19. Conclusão: A pluralização das relações e do entendimento do adoecer foram estí­mulo í  aprendizagem dos princí­pios e atributos da MFC, tornando-se ferramenta potente para os profissionais ressignificarem o cuidar.
DimeRede: desenvolvimento de uma proposta de metodologia para o planejamento e dimensionamento da força de trabalho em saúde
Authors: Dos Santos Carvalho Desirée , Pereira Lelo Nascimento Elisabet
Published: March 2021

Objetivo: Descrever o desenvolvimento de uma metodologia para o planejamento e dimensionamento da força de trabalho multiprofissional em saúde, integrando os três ní­veis da Rede de Atenção í  Saúde (RAS) do Sistema Único de Saúde (SUS); Método: relato de experiência da construção dessa proposta metodológica, realizada entre abril de 2019 e março de 2020, fundamentada nas diretrizes do SUS, na literatura e nas vivências nos projetos do Ministério da Saúde; Resultado: apresentação de uma metodologia, denominada DimeRede que, dirigida ao arranjo organizativo das RAS, estima a força de trabalho necessária de acordo com as necessidades locorregionais, considerando o perfil epidemiológico e os determinantes sociais de saúde e adoecimento identificados em cada estratificação territorial; Conclusão: a DimeRede constitui um avanço importante, mostrando-se potente para instrumentalizar polí­ticas de gestão do trabalho. Contudo, sem encerrar os desafios de garantir equipes adequadas para o cuidado multiprofissional conforme as necessidades de saúde da população.
Atividade fí­sica e modulação do apetite: Os efeitos do exercí­cio fí­sico na supressão do apetite
Authors: De Souza da Silva Everton
Published: March 2021

Objetivo: Discutir ações do exercí­cio fí­sico na modulação do apetite e diminuição da ingestão alimentar identificando mecanismos de supressão do apetite e suas ações anorexí­genas. Método: Realizou-se revisão de literatura no Google Scholar, SciELO, Epub e PubMed, utilizando os descritores de pesquisa: obesity, appetite regulation, physical exercise, e anorexigenic para verificar o estado da arte da temática. Foram incluí­das, majoritariamente, publicações em português e inglês, capí­tulos de livros e artigos cientí­ficos. Resultado: O exercí­cio é uma importante ferramenta para prevenção e tratamento da obesidade, sendo uma eficiente ferramenta para redução da gordura corporal, propiciando ação anorexí­gena com supressão do apetite consequentemente diminuição da ingestão alimentar. Conclusão: O efeito de supressão do apetite gerado pela redução dos ní­veis de grelina não é regra, depende de variáveis. A população estudada, ní­vel de condicionamento e intensidade da atividade são determinantes na obtenção dos efeitos de supressão do apetite e diminuição no consumo alimentar.
Qualidade de vida e bem-estar subjetivo de idosos no programa de academia de saúde
Authors: Basso Bolpato Marieli , Bení­cio da Costa Neto Sebastião , Félix Sousa Ivone
Published: March 2021

Objetivo: levantar o perfil sociodemográfico e as condições de qualidade de vida e bem-estar subjetivo de idosos participantes de academias de saúde investigando as correlações significativas entre esses dados. Método: Trata-se de um estudo transversal desenvolvido no municí­pio de Sinop, Mato Grosso, com 82 idosos, no mês de janeiro de 2019, sendo utilizados os seguintes instrumentos: Questionário Sociodemográfico, WHOQOL-bref, e as escalas: Satisfação com a vida, Bem-Estar de Afetos Positivos e Negativos e Felicidade Subjetiva. Resultados: Quanto melhor a QV no domí­nio fí­sico, melhor a QV nos domí­nios psicológico, relações sociais, meio ambiente, percepção da QV geral, satisfação com a saúde e ao BES relacionado í  satisfação com a vida, aos afetos positivos e í  felicidade, ainda que não se possa afirmar uma causalidade nessas relações. Conclusão: A Academia de Saúde é de suma importância na contribuição de um envelhecimento saudável da população tornando-se uma estratégica para ações de prevenção e promoção de polí­ticas públicas voltadas a população idosa.
Construction of Pedestrian Infrastructure along Transit Corridors
Authors:   University of Illinois at Urbana-Champaign, Braun Lindsay , Barajas Jesus ,   University of Illinois at Urbana-Champaign, Lee Bumsoo ,   University of Illinois at Urbana-Champaign, Martin Rebecca ,   University of Illinois at Urbana-Champaign, Mashraky Rafsun ,   University of Illinois at Urbana-Champaign, Rathor Shubhangi ,   University of Illinois at Urbana-Champaign, Shrivastava Manika ,   University of Illinois at Urbana-Champaign
Published: March 2021

The availability and quality of pedestrian infrastructure play key roles in enabling access to transit. Many transit operators face challenges in facilitating this access, however, because they lack land use authority and encounter other institutional and programmatic impediments to effecting changes in the pedestrian environment. This report identifies the barriers to pedestrian access to transit in suburban communities located in the Pace Suburban Bus service area in northeastern Illinois and suggests potential solutions to overcome these barriers. The research team led several activities to collect data, including: conducting an academic literature review; reviewing pedestrian plans, policies, and programs in the region; surveying and interviewing key stakeholders; reviewing pedestrian funding sources; surveying and conducting case studies of peer transit agencies; conducting physical audits of pedestrian infrastructure; and interviewing residents of six municipalities about their transit access experiences. Lack of adequate funding, difficulties planning across jurisdictional boundaries, and conflicts in transportation priorities are major impediments to building pedestrian infrastructure. While planners and decision-makers tend to value pedestrian planning, challenges such as funding constraints and the need to retrofit suburban infrastructure are key barriers to implementation. Peer transit agencies face similar barriers to Pace and use strategies such as plan and policy development, diverse funding opportunities, and collaborative partnerships with stakeholder agencies and advocacy groups to overcome these barriers. Transit riders generally reported positive experiences with pedestrian access to transit in their communities. Many locations had robust infrastructure, but common deficiencies included poor sidewalk connectivity, incomplete crossings, lack of lighting and transit shelters, and deficiencies in Americans with Disabilities Act (ADA) infrastructure. A suite of policy recommendations for Pace and other partners that focus on planning, policy, funding, interagency coordination, education and training, infrastructure prioritization, and transit amenities address the full range of physical and institutional barriers identified in the research.
Использование искусственных нейронных сетей для распознавания образов уличных сцен
Authors: Галеев Д. Т. , Панищев В. С.
Published: March 2021

Рассмотрена проблематика применения искусственных нейронных сетей для распознавания образов на фотографиях городских улиц, выполнен сравнительный анализ популярных нейросетевых архитектур.
Математическая модель и алгоритмы сегментации и декомпозиции на различные биологические структуры
Authors: Гридин В.Н. , Бубнова И.А. , Труфанов М.И. , Новиков И.А.
Published: March 2021

Одной из ключевых проблем при анализе медицинских и биологических изображений является декомпозиция различных присутствующих на них объектах на отдельные структуры, обусловленные биологическим строением анализируемой области. Эта проблема связана с высокой сложностью и оптической неоднородностью структур как вследствие их природы, так и из-за весьма значительных различий в здоровых тканях в сравнении с такими же структурными элементами для больных пациентов. В данной работе предложен подход к повышению точности выделения биологических структур посредством введения модифицированных дескрипторов для выделения характерных точек на изображениях при отслеживании перемещения краевых частей структуры от оптического среза к оптическому срезу. Отличительной новизной предложенного решения является развитие методологии формирования дескрипторов от двумерного поля распределения яркости к изменению яркости в объеме серии оптических срезов томографического изображения. В качестве источника первичных данных выбран анализ структур головного мозга для локализации гиппокампа, как одной из наиболее сложнолокализуемых и изменчивых структур.
Использование концепции «умный порт» в рамках развития и цифровой трансформации арктической зоны российской федерации
Authors: Бочкарёв П.В. , Кузнецов И. А.
Published: March 2021

Арктическая зона Российской Федерации имеет стратегическое значение для страны. Особое внимание уделяется развитию транспорта и сопутствующей инфраструктуры. Предполагается, что Северный морской путь, который является основной транспортной нитью в Арктическом регионе, будет действовать бесперебойно и круглогодично. Северный морской путь обеспечивает поставки не только в труднодоступные северные районы Российской Федерации, но и способствует международным торговым связям. Высокий износ, устаревание и неразвитость инфраструктуры портов в Арктической зоне Российской Федерации требует создания и внедрения современных комплексных решений, направленных на повышение эффективности функционирования и взаимодействия транспортных, энергетических и информационно-коммуникационных узлов инфраструктуры. Четвертая промышленная революция и цифровизация меняет экономическую структуру регионов России, требуя смены технологического уклада, применения современных решений на базе Интернета вещей, граничных вычислений и интеллектуального анализа данных. Целью работы является формирование концепции «умный порт», ориентированной на управление инфраструктурой портов в Арктической зоне РФ, что позволит повысить пропускную способность, снизить операционные издержки и минимизировать влияние человеческого фактора. Для достижения данной цели необходимо проанализировать существующие проблемы портов Арктического бассейна и их инфраструктуры, рассмотреть существующие бизнес-процессы с учетом особенностей их функционирования в условиях Арктики. В работе была спроектирована модель «умного порта», способствующая поддержке принятия решений в рамках управления основными бизнес-процессами, а также позволяющая проводить мониторинг состояния и предиктивный ремонт объектов инфраструктуры порта с использованием методов прогнозирования. Концепция «умного порта» поможет не только усовершенствовать инфраструктуру портов Арктической зоны путём автоматизации основных операций, но и снизить риски по срыву сроков предоставления услуг и затраты на ремонт инфраструктуры. Необходимо отметить, что развитие арктических портов в рамках представленной концепции «умного порта» будет способствовать цифровой трансформации прилегающих территорий северных регионов Российской Федерации.
Impact of the COVID-19 pandemic on mental health (literature review)
Authors: Tkachenko Olha
Published: March 2021

The coronavirus disease (COVID- 19) caused by the novel Coronavirus strain SARS-CoV-2 was firstly identified in December 2019 in China. Later on, in 3 months it got the status of a global pandemic. The coronavirus disease (COVID-19) posed a number of new challenges and questions for the population, medicine, and particularly for psychiatry. In many cases, it triggered a psychogenic beginning of mental, psychosomatic and somatic diseases. The initial pathogenesis of the mental diseases existing among the population has been complicated and sufficiently distorted due to COVID-19. In addition, it acts as the primary reason for the onset of many still unexplored and unknown illness processes, including mental diseases. Nowadays, the relevance of mental health plays an important role in personal, family, working, or social relationships. The rhythm of life and work in modern world demands stable mental health. It should be active, flexible, with sufficient reserve and rapid recovery. Some mental health disorders with the combination of increased information intensity and amount of communication links often lead even employable young people towards a deep lifelong disability. This pushes their active relatives, medical and social staff to their service. As consequence, these challenges pose a plenty of questions to society about the formation of family, parent and social relationships. As a result, COVID-19 and consequences caused by global pandemic require fast, adequate and in-time reaction from local and global societies. Retarded and unequal response can pose the humanity against diverse outcomes of this tragedy. To resume, it can sufficiently decrease the average level of human health all over the world.
EKSPERIMENTASI MODEL PEMBELAJARAN KOOPERATIF TIPE STUDENT TEAMS ACHIEVEMENT DIVISIONS DAN THINK PAIR AND SHARE TERHADAP KEMAMPUAN PEMAHAMAN KONSEP MATEMATIS SISWA
Authors: Apriliani Intan
Published: March 2021

Penelitian ini bertujuan untuk mengetahui apakah terdapat perbedaan kemampuan pemahaman konsep matematis siswa yang memperoleh perlakuan model pembelajaran Student Teams Achievement Divisions, model pembelajaran Think Pair and Share , dan model pembelajaran Langsung, serta untuk mengetahui model pembelajaran manakah yang lebih baik dari ketiga model pembelajaran tersebut. Penelitian ini menggunakan metode kuasi eksperimen dengan desain penelitian The nonequivalent posttest only control group design.  Populasi dalam penelitian ini adalah seluruh siswa kelas VII SMP Negeri 8 Kota Sukabumi tahun ajaran 2016/2017.  Teknik pengumpulan data yang dilakukan dalam penelitian ini yaitu dokumentasi dan wawancara, instrumen penelitian yang digunakan yaitu lembar observasi dan metode tes. Hasil penelitian menunjukan bahwa: 1) Kemampuan pemahaman konsep matematis siswa yang memperoleh model pembelajaran STAD lebih baik daripada siswa yang memperoleh model pembelajaran TPS; 2) Kemampuan pemahaman konsep matematis siswa yang memperoleh model pembelajaran STAD lebih baik daripada siswa yang memperoleh model pembelajaran langsung.
Etnomatematika: Eksplorasi Alat Musik Tradisional Khas Batak Toba
Authors: Sitanggang Natalia
Published: March 2021

Tujuan dilakukannya penelitian adalah untuk mengeksplorasi hubungan antara matematika dan budaya, khususnya dalam alat musik tradisioan khas Batak Toba. Penelitian ini menggunakan penelitian kualitatif dengan jenis kepustakaan. Hasil yang diperoleh dari penelitian ini menunjukkan bahwa dalam alat musik tradisional khas Batak Toba memiliki berbagai konsep matematika seperti konsep bangun datar dan konsep bangu ruang. Oleh karena itu, alat musik tradisional khas Batak Toba dapat digunakan sebgai sumber belajar matematika pada pembelajaran sekolah dasar dan sekolah menengah pertama. Selain itu dapat mengubah paradigma siswa dan masyarakat bahwa matematika memiliki hubungan dengan kehidupan sehari-hari.
Interseções entre Cinema e Pintura em Maria Antonieta de Sofia Coppola
Authors: Serra Laís Bravo
Published: March 2021

The scene of Sofia Coppola’s movie, Marie Antoinette, is made in dialectic with pictorial works, which occur primarily in three forms: classical painting within diegetic space, as an element of scenography; painting as a scene, when the film picture incorporates the pictorial aesthetics of a canonical work; and the re-appropriation of a canonical painting according to the aesthetic molds of the fictional universe of the film in question, which was placed as scenic object.
La configuración archivística en el cine de no ficción contemporáneo
Authors: Ramos Rubén Marín
Published: March 2021

This article deals with the works of filmmakers and artists who self-impose certain protocols linked to archival configuration to structure and make sense of their films or videos. In this way, collecting, classifying, making lists, series or catalogues will be common practices in this type of work, thus following some of the steps of the art-archive binomial that starts at the beginning of the 20th century with photographic archives such as Augène’s Atget or August Sander and that expands and develops through various artistic practices to this day. Radical documentary pieces with a clear allusion to photography - showing special attention in the portrait and landscape - and where repetitive structures, fixed planes and, in general, a slow rhythm that invites contemplation proliferate. Countenance (2002) by Fiona Tan, Twenty Cigarettes (2011) by James Benning, Ruinas (2009) by Manuel Mozos or Equí y n’otru tiempu (2014) by Ramón Lluís Bande are some of the examples of this cinema that appropriates archival principles, not only to question the very idea of archive, but also as a non-narrative strategy that probes the possibilities of what cinema is and can be.
A MODERN ARCTIC RESOURCE PROJECT FOR RUSSIA'S INDUSTRIAL POLICY: A POLE OF GROWTH FOR THE NATIONAL ECONOMY OR A “CATHEDRAL IN THE DESERT”?
Authors:   Luzin  Institute  for  Economic  Studies,  Federal  Research  Centre “Kola  Science  Centre  of  Russian Academy of Sciences”, Pilyasov A. N. , Putilova E. S. ,   Autonomous Noncommercial Organization “Institute of Regional Consulting”
Published: March 2021

The combination of the types of resource projects and the Arctic spaces in which they are deployed gives four main situations for the industrial policy. It should be maximally active and broad in the first case of a greenfield project, which will demand triple innovation: at the stages of production, processing and transportation. The industrial policy should have a close character in the second case of new industrial areas of double innovation —in processing and logistics. In the third and fourth cases of “rejuvenation” of old industrial areas due to a new resource project or modernization of an old mining enterprise, the main focus of industrial policy is shifted to the regional and municipal levels. In addition to the degree of innovation, activity, with the transition from the first to the fourth type, the priorities of the state industrial policy do also change. In the first case, it is about linking production activity in the Arctic with the work of processing enterprises in the developed zone of Russia, in the second case, about the smart partnership of the state and corporations in new industrial districts, in the third case, about supporting the growth of new types of resource activity as“core” growth “nuclei buildings” in the old industrial area. Finally, in the fourth case, we are talking about the massive use by the state of the mechanisms of “rejuvenation” of the old mining province of the Arctic.
DESIGN OF ENTREPRENEURIAL NETWORKS: EVALUATION OF THE NETWORK POTENTIAL IN RUSSIAN ARCTIC
Authors:   Independent Noncommercial Organization “Institute for Management Research”, Meteleva M. A.
Published: March 2021

The article establishes the relationship between the function of sustainable economic growth in the informational productivity paradigm, which is the basis of the knowledge economy, and the modern interpretation of the economic content of entrepreneurship, which made it possible to draw a conclusion about the system-forming role of entrepreneurship in the formation of new socio-economic relations.In this regard, a refined definition of entrepreneurship based on the distinctive characteristics of its economic content is given. It is concluded that the new properties of informational socio-economic relations, the complication of their configuration and giving entrepreneurship a system-forming role in the knowledge economy, actualize the need for the development of network forms of organizing entrepreneurial activity.Methodological approaches to assessing the usefulness of one or another partner in the process of forming an inter-organizational alliance have been determined. It is proposed in the process of designing entrepreneurial networks to select potential actors using the methodology for assessing the network entrepreneurial potential of socio-economic systems of various levels. The definition of the network entrepreneurial potential of the territory is given.A method for a comprehensive assessment of the network entrepreneurial potential of a territory on the basis of a model that integrates the network entrepreneurial potential of business, the network entrepreneurial potential of civil society, and the network entrepreneurial potential of public administration, has been developed. The article presents a comprehensive assessment of the network entrepreneurial potential of the complex socio-economic system of the territory of the Russian Arctic, carried out using the proposed method. The territories of the Russian Arctic, the most attractive for the formation of entrepreneurial networks, have been identified based on the results of a comprehensive assessment of entrepreneurial potential and entrepreneurial potential of business, civil society and government.
NATURAL PRODUCTIVE FORCES AS THE BASIS OF HYDROPOWER PARADIGMS OF THE RATIONAL DEVELOPMENT OF THE NORTHERN ECONOMY: AN INVITATION TO THE DISCUSSION
Authors:   Institute of Economics, Ural Branch of RAS, Yekaterinburg, Litovskiy V. V.
Published: March 2021

The hydropower potential of natural productive forces has been explored in anticipation of a new technological order with priorities for the development of natural-like technologies and renewable energy sources. This is done to select an adequate energy paradigm for the development of the remote northern territories and the shelf. The analysis of the hydropower industry of the Kola Peninsula shows its strengths and weaknesses in this aspect. The vectors of possible improvement of the used and promising innovations, spatial and territorial development paradigms, tools for locating the economy, taking into account the geographic specifics of the involved hydropower resources, have been determined. This aspect shows the costs of the existing nature management, the most acute problems associated with the irrational use of natural resources in the Soviet period. Within the framework of the original author's graviogeographic method, the priorities of modern nature management are highlighted, oriented towards modern nature-like hydropower technologies and a more verified functional use of economic space. Particular attention is paid to the description of the development of one of the most promising nature-like energetics, now actively developing in the world —the wave energy, the assessment of its hydro potential for the development of the remote coastal territories and the shelf of the Russian North and the Arctic. Taking this into account, using particular examples of analyzing the use of the potential of the hydrotechnical and water-energy resources of the Kola Peninsula, specific directions and options for promising hydropower developments for the proper maintenance of the Arctic zone of the Russian Federation, thematic fields for cooperation among regions and joining efforts in the implementation of such ambitious projects are shown.