bluuebunny/crossref_metadata_2025 huggingface dataset:
[Retracted] Discussion on Basic Japanese Teaching Mode in Multimedia Network Environment
Authors: Xia JianXue
Published: July 2022

With the development of the information age and the progress of science and technology, the traditional education model cannot meet the needs of teachers and students for richer knowledge and diversified teaching methods in the new era. The traditional basic Japanese teaching mode has not matched with the current form of social development. Therefore, it is urgent to establish a new basic Japanese teaching model. The development of multimedia brings the Internet mixed teaching mode, which just fills the gap of this kind of teaching method and provides new ideas and ways for the reform of teaching methods. The application of multimedia network assisted teaching in basic Japanese teaching plays a great role in promoting basic Japanese teaching. In the multimedia network environment, how to let students learn independently, find and raise problems by themselves, and analyze and solve problems at a deeper level has attracted the attention of many educators. Improving the practicability of Japanese teaching is very important for Japanese teaching in colleges and universities. Therefore, this paper studies media teaching, analyzes the current and existing problems of multimedia teaching in Japanese teaching and the principles that should be followed in order to develop, finds the limitations of using multimedia teaching methods in the current Japanese teaching and learning process, and puts forward targeted suggestions and application strategies on these limitations, and builds a new model of basic Japanese teaching under the multimedia network environment.
Effects of Autologous Platelet-Rich Plasma on Healing of Peptic Ulcers: A Randomized Controlled Trial
Authors: Xu Ting , Tian Yin , Wang Yi , Yi Zhongmei , Li Chenchen , Wang Shichun , Fan Yahan , Yao Chunyan , Peng Guiyong , Lu Hua
Published: July 2022

Purpose. Peptic ulcer is a multifactorial and complex disease and affects a wide range of people worldwide. We provided a novel therapeutic approach for peptic ulcer and observed its effect. Methods. Peptic ulcer patients were enrolled from 2016 to 2017 in Chongqing and randomly assigned to two groups: a control group that used only rabeprazole and a platelet-rich plasma (PRP) group that received a combination therapy of autologous PRP (aPRP) and rabeprazole. The therapeutic effect was assessed via the ulcer size and symptom score. Results. A total of 27 patients were included (12 patients in the control group and 15 patients in the PRP group) in this study. Our results showed that all participants have healed in 30 days, and there was no significant difference in healing time between the PRP group and the control group in different independent variables. However, regression analysis revealed that the healing time was 6.99 days shorter in the PRP group than that in the control group, and patients with higher symptom scores in the initial examination need more time to heal during treatment. Endoscopic results showed that the repaired ulcer in the PRP group was more similar to the normal gastric mucosa tissue than that the control group. Conclusion. This study showed an encouraging preliminary result that aPRP has a positive result in patients with peptic ulcer and seems to be a better choice for refractory peptic ulcer treatment. Although further follow-up studies are needed to determine the duration of efficacy of aPRP, the approach will be helpful in improving the clinical treatment of peptic ulcer.
[Retracted] Chemical Composition and Biological Evaluation of Typha domingensis Pers. to Ameliorate Health Pathologies: In Vitro and In Silico Approaches
Authors: Dilshad Rizwana , Khan Kashif-ur-Rehman , Saeed Laiba , Sherif Asmaa E. , Ahmad Saeed , Ovatlarnporn Chitchamai , Nasim Jawad , Hussain Musaddique , Ghalloo Bilal Ahmad , Basit Abdul , Mukhtar Imran
Published: July 2022

Human diseases are becoming more prevalent, necessitating the development of modalities to overcome the challenges of treating various disorders. In the current research, we analyzed the biomedicinal role of Typha domingensis which is an important medicinal plant. The species is traditionally used in the treatment of neurological disorders and skin malignancies. The chloroform (CFTD) and n‐butanol fractions of T. domingensis (BFTD) were subjected to chemical profiling through the determination of total polyphenolic contents and GC‐MS analysis. The oral toxicity test was applied to investigate the toxicity of the extracts. Antioxidant capacity was analyzed by four in vitro methods: DPPH, ABTS, FRAP, and CUPRAC. The pharmacological potential was evaluated through clinically significant enzyme inhibition assays, thrombolytic, and antimicrobial activities. In silico molecular docking approach was applied to confirm the role of T. domingensis against the enzymes. The polyphenolic quantification revealed that the BFTD was comparatively rich in total phenolic and flavonoid contents (97.14 milligrams gallic acid equivalent (mg GAE/g) and 362.5 milligrams quercetin equivalent per gram of dry extract (mg QE/g DE), respectively), as compared to the CFTD. The GC‐MS analysis of the CFTD and BFTD resulted in the tentative identification of 67 and 29 compounds, respectively, with the major components of fatty acids and essential oil. The oral toxicity test revealed the safety and biocompatibility of CFTD and BFTD. Both the fractions showed promising antioxidant activity. Tyrosinase was found as the major enzyme inhibited by BFTD (78.67%) and CFTD (68.09%), whereas the standard kojic acid showed 85.58% inhibition. The inhibition results of acetylcholinesterase and butyrylcholinesterase by BFTD (71.65 and 60.79%, respectively) are higher than CFTD. Both the fractions were found active against various strains of bacteria. Furthermore, the molecular docking studies of the compounds showed a good docking score against all the docked enzymes among which deoxycaesaldekarin C was found with the highest binding affinities in comparison to the standard. The current study suggests that T. domingensis is nontoxic and can be a potential source of phytoconstituents with promising pharmacological potential.
Intelligent Face Recognition System Based on Universal Design Concept
Authors: Li Zhijie , Shin Kibong
Published: July 2022

The rapid development of science and technology, i.e., integrated modules that are actuators and sensors, promotes the comprehensive popularization of intelligent products in people’s life. More particularly, with the advent of the hybrid of the Internet of things and artificial intelligence, more and more activities preferably linked to the human beings have been automated and developed. Among those fields, intelligent face recognition has also become a basic technology in work and life. This technology has been widely used in various products and is well known by people. However, the intelligent face recognition system developed at present lacks universal design concept, and the designed system cannot be applied to various products. During the use of users, there are some problems, such as difficult operation and unfriendly interface. In order to improve the satisfaction of users’ physical examination and the accuracy of intelligent face recognition, this study develops an intelligent face recognition system based on the universal design concept. First, the universal design concept is briefly described, and the calculation process of face detection algorithm and face detection algorithm based on the optical flow method is introduced in detail. Then, when designing a face recognition system, this algorithm is used to build a complete system framework. The main functional modules in this system are face detection module, face recognition module, and face training module. The functions of each module are described in detail. Finally, the face feature extraction results of the face detection algorithm based on the optical flow method are verified on the Yale face database and PIE face database. The results show that the algorithm has the highest detection and recognition rate. At the same time, the ORL face database is used to compare and analyze the system performance. The face image recognition rate of this algorithm is 92, which is the highest compared with other algorithms.
Early Warning of Enterprise Financial Risk Based on Decision Tree Algorithm
Authors: Hong Sen , Wu Han , Xu Xiujuan , Xiong Wei
Published: July 2022

To improve enterprise financial early warning, we propose an algorithm based on a decision tree. According to the shortcomings and defects of the classical algorithm and the traditional decision tree algorithm, in the ordinary decision tree improved algorithm based on PCA, there is a problem that the representativeness of the data after dimensionality reduction processing are not high, resulting in the fact that the accuracy of the algorithm can be improved slightly after multiple data runs. Based on the classical algorithm, attribute eigenvalues before classification are extracted twice, and the amount of data to be classified is calculated. That is, the most important attributes of the original data are selected. After the subtree is established, the dimension reduction and merging selection of the data are performed, and the improved algorithm is verified by using three data sets in the UCI database. The results show that the average accuracy in the three datasets is 94.6%, which is improved by 1.6% and 0.6% for the traditional classical algorithm and the ordinary PCA decision tree optimization algorithm, respectively. PCA-based decision tree algorithms can improve the accuracy of the results to some extent, which is of practical importance. In the future, a classic algorithm improved for secondary modeling will be used to obtain a more efficient decision tree model. The decision tree algorithm has been proven to recognize an early warning of an enterprise’s financial risks, which enhances the effectiveness of an enterprise’s early financial warning.
Analysis and Design of the Project Risk Management System Based on the Fuzzy Clustering Algorithm
Authors: Zhong Ping , Yin Hang , Li Yuanfu
Published: July 2022

In order to effectively control the cost risk of power grid construction projects, the author proposes a cost risk management system for power grid construction projects based on the fuzzy clustering algorithm. The system introduces the fuzzy clustering maximum tree algorithm, and by constructing a mathematical model, combined with the empirical analysis, the key risk factors in the cost risk of power grid construction projects are identified. Through the analysis, it can be concluded that the key risks in the cost risk of power grid construction projects are the planning risks of infrastructure projects, the research risks of infrastructure projects, and the cost risks of infrastructure projects. Experimental results show that combined with expert experience and the actual situation of power grid engineering, the classification result at threshold

λ
=
0.785

becomes more realistic. At this

λ

level, 6 risk factors are grouped into 4 categories as follows: class I

x

1

,

x

2

,

x

4

, class II

x

3

, class III

x

5

, and class IV

x

6

. Through research, the identification of key risks can enable project managers to control the cost of power grid construction projects, targeted, so that risks can be minimized and investment returns can be improved.
Network Data Mining Algorithm of Associated Users Based on Multi-Information Fusion
Authors: Wang Yuechun , Zhang Suzhen , Zhang Shaofang
Published: July 2022

To explore how related users can optimize the network mining algorithm, the author proposes a related user mining algorithm based on the fusion of user attributes and user relationships. This method recommends key technical problems and solutions based on information represented by multi-information fusion and explores research on associated user network data mining algorithms. Research has shown that the associated user network data mining algorithm based on multi-information fusion is 65% higher than previous methods. AUMA-MRL has good performance under different network overlaps. Also, since the node embedding of the AUMA-MRL algorithm is obtained by neighborhood sampling, for new nodes in the network, the algorithm can quickly obtain the new node embedding, as well as the similarity vector between the new node and the rest of the nodes in the network, therefore, the associated users of newly added nodes in the network can be quickly mined, and the robustness of the mining algorithm of associated users in the network is enhanced. Compared with the existing classical algorithms, the recall rate of the proposed algorithm is increased by 17.5% on average, which can effectively mine the associated users in the network.
The Coronary Angiography-Derived Index of Microcirculatory Resistance Predicts Left Ventricular Performance Recovery in Patients with ST-Segment Elevation Myocardial Infarction
Authors: Hou Chang , Guo Meng , Ma Yuliang , Li Qi , Liu Chuanfen , Lu Mingyu , Zhao Hong , Liu Jian
Published: July 2022

Objectives. The present study is designed to investigate the impact of coronary angiography-derived index of microcirculatory resistance (caIMR) on left ventricular performance recovery. Background. IMR has been established as a gold standard for coronary microvascular assessment and a predictor of left ventricular recovery after ST-segment elevation myocardial infarction (STEMI). CaIMR is a novel and accurate alternative of IMR. Methods. The present study retrospectively included 80 patients with STEMI who underwent primary percutaneous coronary intervention (PCI). We offline performed the post-PCI caIMR analysis of the culprit vessel. Echocardiography was performed within the first 24 hours and at 3 months after the index procedure. Left ventricular recovery was defined as the change in left ventricular ejection fraction (LVEF) more than zero. Results. The mean age of the patients was 58.0 years with 80.0% male. The average post-PCI caIMR was 43.2. Overall left ventricular recovery was seen in 41 patients. Post-PCI caIMR (OR: 0.948, 95% CI: 0.916–0.981, p = 0.002), left anterior descending as the culprit vessel (OR: 3.605, 95% CI: 1.23–10.567, p = 0.019), and male (OR: 0.254, 95% CI: 0.066–0.979, p = 0.047) were independent predictors of left ventricular recovery at 3 months follow-up. A predictive model was established with the best cutoff value for the prediction of left ventricular recovery 2.33 (sensitivity 0.610, specificity 0.897, and area under the curve 0.765). In patients with a predictive model score less than 2.33, the LVEF increased significantly at 3 months. Conclusions. The post-PCI caIMR can accurately predict left ventricular functional recovery at 3 months follow-up in patients with STEMI treated by primary PCI, supporting its use in clinical practice.
β2-Microglobulin Maintains Glioblastoma Stem Cells and Induces M2-like Polarization of Tumor-Associated Macrophages
Authors: Li Daqi , Zhang Qian , Li Lu , Chen Kexin , Yang Junlei , Dixit Deobrat , Gimple Ryan C. , Ci Shusheng , Lu Chenfei , Hu Lang , Gao Jiancheng , Shan Danyang , Li Yangqing , Zhang Junxia , Shi Zhumei , Gu Danling , Yuan Wei , Wu Qiulian , Yang Kailin , Zhao Linjie , Qiu Zhixin , Lv Deguan , Gao Wei , Yang Hui , Lin Fan , Wang Qianghu , Man Jianghong , Li Chaojun , Tao Weiwei , Agnihotri Sameer , Qian Xu , Shi Yu , You Yongping , Zhang Nu , Rich Jeremy N. , Wang Xiuxing
Published: July 2022

Glioblastoma (GBM) is a complex ecosystem that includes a heterogeneous tumor population and the tumor-immune microenvironment (TIME), prominently containing tumor-associated macrophages (TAM) and microglia. Here, we demonstrated that β2-microglobulin (B2M), a subunit of the class I major histocompatibility complex (MHC-I), promotes the maintenance of stem-like neoplastic populations and reprograms the TIME to an anti-inflammatory, tumor-promoting state. B2M activated PI3K/AKT/mTOR signaling by interacting with PIP5K1A in GBM stem cells (GSC) and promoting MYC-induced secretion of transforming growth factor-β1 (TGFβ1). Inhibition of B2M attenuated GSC survival, self-renewal, and tumor growth. B2M-induced TGFβ1 secretion activated paracrine SMAD and PI3K/AKT signaling in TAMs and promoted an M2-like macrophage phenotype. These findings reveal tumor-promoting functions of B2M and suggest that targeting B2M or its downstream axis may provide an effective approach for treating GBM.

Significance:

β2-microglobulin signaling in glioblastoma cells activates a PI3K/AKT/MYC/TGFβ1 axis that maintains stem cells and induces M2-like macrophage polarization, highlighting potential therapeutic strategies for targeting tumor cells and the immunosuppressive microenvironment in glioblastoma.
Hyperemesis Gravidarum and the Potential for Cancer: A Longitudinal Cohort Study over Three Decades
Authors: Marcoux Sophie , Leduc Valérie , Healy-Profitós Jessica , Bilodeau-Bertrand Marianne , Auger Nathalie
Published: July 2022

Background:

Our objective was to assess whether hyperemesis gravidarum is associated with the risk of endodermal, mesodermal, and ectodermal human chorionic gonadotropin (hCG) receptor+ cancer in women.

Methods:

We performed a longitudinal cohort study of 1,343,040 women who were pregnant between 1989 and 2019 in Quebec, Canada. We identified women with and without hyperemesis gravidarum and followed them over time to capture incident cancers, grouped by embryonic germ cell layer of origin and organ hCG receptor positivity. We used time-varying Cox regression to model hazard ratios (HR) and 95% confidence intervals (CI) for the association between hyperemesis gravidarum and cancer onset, adjusted for maternal age, comorbidity, multiple gestation, fetal congenital anomaly, socioeconomic deprivation, and time period.

Results:

Women with hyperemesis gravidarum had a greater risk of endodermal cancer compared with no hyperemesis gravidarum (5.8 vs. 4.8 per 10,000 person-years; HR, 1.36; 95% CI, 1.17–1.57), but not mesodermal or ectodermal cancer. Severe hyperemesis with metabolic disturbance was more strongly associated with cancer from the endodermal germ layer (HR, 1.97; 95% CI, 1.51–2.58). The association between hyperemesis gravidarum and endodermal cancer was driven by bladder (HR, 2.49; 95% CI, 1.37–4.53), colorectal (HR, 1.41; 95% CI, 1.08–1.84), and thyroid (HR, 1.43; 95% CI, 1.09–1.64) cancer.

Conclusions:

Women with hyperemesis gravidarum have an increased risk of cancers arising from the endodermal germ cell layer, particularly bladder, colorectal, and thyroid cancers.

Impact:

Future studies identifying the pathways linking hyperemesis gravidarum with endodermal tumors may help improve the detection and management of cancer in women.
Novel DNA Methylation Biomarker Panel for Detection of Esophageal Adenocarcinoma and High-Grade Dysplasia
Authors: Yu Ming , Moinova Helen R. , Willbanks Amber , Cannon Victoria K. , Wang Ting , Carter Kelly , Kaz Andrew , Reddi Deepti , Inadomi John , Luebeck Georg , Iyer Prasad G. , Canto Marcia I. , Wang Jean S. , Shaheen Nicholas J. , Thota Prashanti N. , Willis Joseph E. , LaFramboise Thomas , Chak Amitabh , Markowitz Sanford D. , Grady William M.
Published: July 2022

Purpose:

Current endoscopy-based screening and surveillance programs have not been proven effective at decreasing esophageal adenocarcinoma (EAC) mortality, creating an unmet need for effective molecular tests for early detection of this highly lethal cancer. We conducted a genome-wide methylation screen to identify novel methylation markers that distinguish EAC and high-grade dysplasia (HGD) from normal squamous epithelium (SQ) or nondysplastic Barrett's esophagus (NDBE).

Experimental Design:

DNA methylation profiling of samples from SQ, NDBE, HGD, and EAC was performed using HM450 methylation arrays (Illumina) and reduced-representation bisulfate sequencing. Ultrasensitive methylation-specific droplet digital PCR and next-generation sequencing (NGS)-based bisulfite-sequencing assays were developed to detect the methylation level of candidate CpGs in independent esophageal biopsy and endoscopic brushing samples.

Results:

Five candidate methylation markers were significantly hypermethylated in HGD/EAC samples compared with SQ or NDBE (P < 0.01) in both esophageal biopsy and endoscopic brushing samples. In an independent set of brushing samples used to construct biomarker panels, a four-marker panel (model 1) demonstrated sensitivity of 85.0% and 90.8% for HGD and EACs respectively, with 84.2% and 97.9% specificity for NDBE and SQ respectively. In a validation set of brushing samples, the panel achieved sensitivity of 80% and 82.5% for HGD and EAC respectively, at specificity of 67.6% and 96.3% for NDBE and SQ samples.

Conclusions:

A novel DNA methylation marker panel differentiates HGD/EAC from SQ/NDBE. DNA-methylation–based molecular assays hold promise for the detection of HGD/EAC using esophageal brushing samples.
Effects of NCSTN Mutation on Hair Follicle Components in Mice
Authors: Shi Tian-wei , Cao Wei , Zhao Qing-zan , Yu Hong-xing , Zhang Si-Sen , Hao Yi-bin
Published: July 2022

Background and Objectives: Hidradenitis suppurativa (HS)/acne inversa is an intractable skin disease that is characterized by destructive lesions – primarily on the flexural areas. Although its etiology is unknown, genetics is considered to be a factor of its pathology – mutations in γ-secretase genes have been identified in certain familial HS patients, and follicular occlusion is widely accepted as the primary cause of HS. But, no relationship between these mutations and the components of hair follicles has been reported. Thus, we examined changes in these components in mice with a mutation in NCSTN (a γ-secretase gene). Methods: We generated C57BL/6 mice with an NCSTN mutation and examined their expression of hair cortex cytokeratin and trichohyalin by Western blot and immunohistochemistry, in addition to nicastrin, the product of NCSTN, and NICD compared with wild-type mice. The structure of hair follicles was analyzed by hematoxylin-eosin staining and transmission electron microscopy. Results: In mice with an NCSTN mutation, HS-like skin lesions appeared after age 6 months, the pathological manifestations of which were consistent with the features of human HS. The structure of hair follicles was abnormal in mice with an NCSTN mutation versus wild-type mice, and hair cortex cytokeratin, trichohyalin, nicastrin, and NICD were downregulated in these mice. Conclusions: This NCSTN mutant mouse model could be an improved model to study early lesion development aspects of human HS pathogenesis and could perhaps be a better alternative for evaluating early-acting and preventive therapeutics for HS experimentally before clinical trials in HS patients. NCSTN mutations disrupt the development of hair follicles, leading to abnormal hair follicle structures, perhaps resulting in the onset of HS.
Pavlovian-to-Instrumental Transfer across Mental Disorders: A Review
Authors: Garbusow Maria , Ebrahimi Claudia , Riemerschmid Carlotta , Daldrup Luisa , Rothkirch Marcus , Chen Ke , Chen Hao , Belanger Matthew J. , Hentschel Angela , Smolka Michael N. , Heinz Andreas , Pilhatsch Maximilan , Rapp Michael A.
Published: July 2022

A mechanism known as Pavlovian-to-instrumental transfer (PIT) describes a phenomenon by which the values of environmental cues acquired through Pavlovian conditioning can motivate instrumental behavior. PIT may be one basic mechanism of action control that can characterize mental disorders on a dimensional level beyond current classification systems. Therefore, we review human PIT studies investigating subclinical and clinical mental syndromes. The literature prevails an inhomogeneous picture concerning PIT. While enhanced PIT effects seem to be present in non-substance-related disorders, overweight people, and most studies with AUD patients, no altered PIT effects were reported in tobacco use disorder and obesity. Regarding AUD and relapsing alcohol-dependent patients, there is mixed evidence of enhanced or no PIT effects. Additionally, there is evidence for aberrant corticostriatal activation and genetic risk, e.g., in association with high-risk alcohol consumption and relapse after alcohol detoxification. In patients with anorexia nervosa, stronger PIT effects elicited by low caloric stimuli were associated with increased disease severity. In patients with depression, enhanced aversive PIT effects and a loss of action-specificity associated with poorer treatment outcomes were reported. Schizophrenic patients showed disrupted specific but intact general PIT effects. Patients with chronic back pain showed reduced PIT effects. We provide possible reasons to understand heterogeneity in PIT effects within and across mental disorders. Further, we strengthen the importance of reliable experimental tasks and provide test-retest data of a PIT task showing moderate to good reliability. Finally, we point toward stress as a possible underlying factor that may explain stronger PIT effects in mental disorders, as there is some evidence that stress per se interacts with the impact of environmental cues on behavior by selectively increasing cue-triggered wanting. To conclude, we discuss the results of the literature review in the light of Research Domain Criteria, suggesting future studies that comprehensively assess PIT across psychopathological dimensions.
Sex Hormones in Males and Females with Active Central Serous Chorioretinopathy
Authors: Brinks Joost , van Dijk Elon H.C. , Tsonaka Roula , Meijer Onno C. , Boon Camiel J.F.
Published: July 2022

Purpose: The aim of the study was to assess the role of sex hormones in male and female patients with central serous chorioretinopathy (CSC), a disease with a pronounced male predilection. Methods: A total of 206 chronic CSC patients (183 males, 23 females) and 59 healthy controls (29 males, 30 females) were enrolled. Serum testosterone, estradiol, albumin, and sex hormone-binding globulin levels were determined using immunoassays. The free fraction of testosterone and the free testosterone/estradiol ratio were calculated. Results: No differences in the levels of total testosterone and estradiol were observed between CSC patients and healthy controls. Albumin levels were found to be lower in male CSC patients compared to controls (controls 47.8 g/L, patients 46.0 g/L, adj. p = 0.006). Only in females with CSC, sex hormone-binding globulin levels were found to be lower (controls 94.2 nmol/L, patients 50.4 nmol/L, adj. p = 0.001), together with a higher free testosterone/estradiol ratio (controls 0.06, patients 0.18, adj. p = 0.018). Conclusions: In this study, we did not find evidence for a disturbance in sex hormone levels in males with CSC. The lower levels of sex hormone-binding globulin in females with CSC, leading to a disturbed free testosterone/estradiol ratio, warrant further investigation into the role of androgens in females with CSC.
O lugar da poesia de Violeta Branca na produção literária amazonense do século XX
Authors: Cordeiro Elcione Sousa da Silva , Costa Veronica Prudente , Wankler Cátia Monteiro
Published: July 2022

A literatura amazonense possui uma produção literária significativa, mas os poucos escritos científicos sobre ela mostram-na como uma literatura tímida e desconhecida. As obras de maior destaque são aquelas escritas por homens, e as mulheres, que também contribuíram para esse reconhecimento, são silenciadas e esquecidas. O presente artigo visa apresentar Violeta Branca, a primeira poeta a inaugurar a escrita literária feminina neste estado. Ela enfrentou os preconceitos, correu riscos sociais, quebrou tabus, inovou e com seus sonhos de liberdade fez história. Violeta tornou-se a primeira mulher a ingressar na Academia Amazonense de Letras em 1937.
“Noite de almirante” de Machado de Assis: um povo de subúrbio
Authors: Silva Eufrida Pereira da
Published: July 2022

"Noite de almirante", de Machado de Assis, foi publicado em 1884 na Gazeta de Notícias do Rio de Janeiro e em Histórias sem Data no mesmo ano. No conto, um triângulo amoroso é vivido por um povo de subúrbio como Genoveva, Deolindo e José Diogo. Deolindo, ao saber que foi traído, ele que fez juras de amor, passou a fazer promessas de morte. O caráter frívolo da moça, a farsa da noite de almirante e a vida imprevisível do mascate mundo afora formam um turbilhão que colide com os ideários dos discursos inaugurais de  uma nação recém-independente com pretensões de unidade, civilização e ordem. A discussão é tratada segundo Schwarz (2000), DaMatta (1997), Candido (1970) e Schwarcz (2000).
“O que está em jogo quando insistimos tanto que a subalterna fala?” Problemas tradutórios e epistemológicos do ensaio de Gayatri Spivak no Brasil
Authors: Ribeiro Natália Lima , Pressler Gunter Karl
Published: July 2022

A repercussão do ensaio de Gayatri Spivak Can the Subaltern Speak? (1985/1988) foi internacionalmente grande, mas menos conhecida é sua modificação sobre a visão interpretativa do termo “sujeito subalterno” no livro A Critique of Postcolonial Reason (1999), na parte “História”. Em 2000, a autora participou do congresso da ABRALIC (Terra & Gentes), em Salvador da Bahia, mas não deixou rastros no Brasil - até a tradução do ensaio como livro, Pode o Subalterno falar?, pela editora da UFMG, em 2010. O artigo proposto acrescenta a nova conclusão, a fim de completar a importância da revisão da autora sobre seu posicionamento no debate sobre a subalternidade.
Autoria negra no cinema norte-americano: leituras sobre insurreições negras contra a violência total e as reiterações do evento racial
Authors: Lopes Estefânia Francis
Published: July 2022

Apresentamos uma análise sobre autoria negra no cinema, procurando refletir quanto à reiteração do evento racial, como também sobre as insurreições frente à violência total a que as pessoas negras estão submetidas cotidianamente, conforme as reflexões de Denise Ferreira da Silva (2016). Iniciamos por uma breve retrospectiva, por meio de uma seleção de narrativas cinematográficas estadunidenses, depois, nos centramos no curta-metragem Dois estranhos (2020), de Travon Free e Martin Desmond Roe, e finalizamos com narrativas protagonizadas por pessoas negras tanto no audiovisual estadunidense quanto no brasileiro.
Procedural Characteristics of Intravascular Ultrasound–Guided Percutaneous Coronary Intervention and Their Clinical Implications
Authors: Lee Seung‐Yul , Zhang Jun‐Jie , Mintz Gary S. , Hong Sung‐Jin , Ahn Chul‐Min , Kim Jung‐Sun , Kim Byeong‐Keuk , Ko Young‐Guk , Choi Donghoon , Jang Yangsoo , Kan Jing , Pan Tao , Gao Xiaofei , Ge Zhen , Chen Shao‐Liang , Hong Myeong‐Ki
Published: July 2022

Background

Despite the clinical benefits to intravascular ultrasound (IVUS) guidance for percutaneous coronary intervention (PCI), most patients with coronary artery disease undergo angiography‐guided PCI alone in the real‐world setting. We sought to investigate the procedural characteristics of IVUS‐guided PCI and their clinical outcomes, as compared with angiography‐guided PCI.

Methods and Results

This was a cohort study using patient‐level data from the IVUS‐XPL (Impact of Intravascular Ultrasound Guidance on the Outcomes of Xience Prime Stents in Long Lesions) and ULTIMATE (Intravascular Ultrasound Guided Drug Eluting Stents Implantation in All‐Comers Coronary Lesions) clinical trials. A total of 2848 patients with 3872 native coronary lesions were included and procedural characteristics assessed by quantitative coronary angiography (QCA) were compared between IVUS and angiography guidance. Stent‐to‐reference vessel diameter ratio (ie, QCA stent sizing) was greater (1.11±0.16 versus 1.07±0.14,
P
<0.001) and high‐pressure postdilation was more frequently performed (83.7% versus 75.4%,
P
<0.001) with IVUS guidance, whereas residual stent edge dissections were more frequent in lesions treated with IVUS guidance (4.6% versus 0.7%,
P
<0.001). Given the dissection risk, optimal QCA stent sizing for IVUS guidance was a stent‐to‐QCA reference vessel diameter ratio ≥1.1 to <1.3. Among 1424 patients (1969 lesions) treated with angiography guidance, QCA stent sizing <1.0 was observed in 651 (33.1%) lesions, while QCA stent sizing ≥1.1 to <1.3 was observed in only 526 (26.7%) lesions. Under angiography guidance, patients with both QCA stent sizing ≥1.1 to <1.3 and high‐pressure postdilation (235 of 1424, 16.5%) had a lower risk of 3‐year target lesion failure compared with others (hazard ratio, 0.532; 95% CI, 0.293–0.966 [
P
=0.038]).

Conclusions

IVUS‐guided PCI resulted in larger QCA‐assessed stent sizing and more frequent postdilation with high‐pressure inflations. These procedures may further improve long‐term clinical outcomes in patients undergoing PCI without IVUS.

Registration

URL:
https://www.clinicaltrials.gov
; Unique identifier: NCT01308281 (IVUS‐XPL); NCT02215915 (ULTIMATE).
Atrial Fibrillation and the Risk of Early‐Onset Dementia: A Systematic Review and Meta‐Analysis
Authors: Giannone Maria Edvige , Filippini Tommaso , Whelton Paul K. , Chiari Annalisa , Vitolo Marco , Boriani Giuseppe , Vinceti Marco
Published: July 2022

Background

Recent studies have identified an increased risk of dementia in patients with atrial fibrillation (AF). However, both AF and dementia usually manifest late in life. Few studies have investigated this association in adults with early‐onset dementia. The aim of this study was to investigate the relationship between AF and early‐onset dementia.

Methods and Results

We searched the PubMed/MEDLINE, Embase, and Scopus databases through April 15, 2022, for studies reporting on the association between AF and dementia in adults aged <70 years, without language restrictions. Two reviewers independently performed the study selection, assessed the risk of bias, and extracted the study data. We performed a meta‐analysis of early‐onset dementia risk according to occurrence of AF using a random‐effects model. We retrieved and screened 1006 potentially eligible studies. We examined the full text of 33 studies and selected the 6 studies that met our inclusion criteria. The pooled analysis of their results showed an increased risk of developing dementia in individuals with AF, with a summary relative risk of 1.50 (95% CI, 1.00–2.26) in patients aged <70 years, and 1.06 (95% CI, 0.55–2.06) in those aged <65 years.

Conclusions

In this systematic review and meta‐analysis, AF was a risk factor for dementia in adults aged <70 years, with an indication of a slight and statistically imprecise excess risk already at ages <65 years. Further research is needed to assess which characteristics of the arrhythmia and which mechanisms play a role in this relationship.
Annotated checklist of Hydraenidae (Coleoptera, Polyphaga) of Brazil
Authors: BENETTI CESAR J. , HAMADA NEUSA
Published: July 2022

A checklist of known species of the water beetle Hydraenidae (minute moss beetles) recorded from Brazil is assembled, rendering a total of 34 species distributed in four genera: Adelphydraena Perkins, 1989 (one species), Hydraena Kugelann, 1794 (19 species), Parhydraenida J. Balfour-Browne, 1975 (11 species) and Ochthebius Leach, 1815 (three species). For each taxon a complete account of its nomenclature, including synonyms and historical name combinations are included. The habitats (when known) and geographical distribution of each species organized by Brazilian states are also provided.
Eustrophus praecursor sp. nov.: the first Eocene species of Eustrophinae (Coleoptera: Tetratomidae) from Baltic amber
Authors: ALEKSEEV VITALII I. , BUKEJS ANDRIS
Published: July 2022

Based on well-preserved specimen in Baltic amber (the Kaliningrad Region, Russia), a new polypore fungus beetle of the extant Holarctic genus Eustrophus Illiger, E. praecursor sp. nov. is described and illustrated. It is the first described Cenozoic member of the subfamily Eustrophinae. This fossil record expands the diversity of Tetratomidae known to occur in the Eocene “amber forest”. A checklist of described fossil Tetratomidae is provided.
Operative Rib Fixation at a Rural Trauma Center
Authors: Feyh Andrew , Kocher Tim , Smith Dylan , Amiri Farzad , Denning David
Published: July 2022

Introduction

Operative rib fixation is becoming more common in the management of rib fractures, with studies showing benefits of surgery in decreasing time on mechanical ventilation, ICU and total hospital length of stay, and mortality. This paper will review the data from our institution to determine if these benefits were seen in our trauma population.

Methods

A retrospective review of the institution’s trauma database was conducted, including operative patients (n = 36), control patients (nonoperative patients from October 2018 to October 2019, n = 207), and selected control patients based on similar injury severity score range as operative patients (n = 181). Data reviewed included time on mechanical ventilation, ICU and total hospital length of stay, and disposition at discharge, including mortalities. Operative complications were also reviewed.

Results

The operative group had a higher ISS compared to both controls, longer average time on mechanical ventilation, longer average ICU and total hospital length of stay, and a higher percentage of patients discharged to inpatient facilities. However, the operative group had lower mortality compared to the control groups. The operative group had 3 surgical site infections requiring readmission and hardware removal.

Discussion

Unlike other studies, our operative patients did not see improvements in time on mechanical ventilation, ICU and total hospital length of stay, or disposition at discharge, but did see a mortality benefit. Confounding factors include higher average ISS in the operative group, and over-sedation in the ICU. Data collection is ongoing, and refinements are being made to perioperative and ICU management to minimize these confounding variables.
Electric Vehicles Are a Platform Business: What Firms Need to Know
Authors: Anderson Edward G. , Bhargava Hemant K. , Boehm Jonas , Parker Geoffrey
Published: July 2022

Many of the most successful firms—such as Alibaba, Google, and Uber—operate platforms. Electric vehicles (EVs) are platform goods as well because value comes from the vehicle plus complementary providers. Gasoline vehicles are also platform goods, but managers in the industry can ignore that because the refueling network is mature. However, temporal and structural differences in network effects for electric vehicles make it crucial for EV firms to incorporate platform strategies. This article explains these differences and outlines the key platform strategy decisions that EV firms need to make, including platform network coordination, launch, and openness.
Literary and religious history from the middle: Merchants and bhakti in early modern North India
Authors: Williams Tyler W.
Published: July 2022

This article examines the hagiographical writings of two religious communities, that is, the Dadu Panth and the Niranjani Sampraday, in what is now known as Rajasthan, during the seventeenth and eighteenth centuries in order to illuminate how their monastic and lay members, particularly merchants and ‘scribal’ communities, imagined their religious, social and political worlds. The role of merchant and scribal groups in the origin and development of such so-called ‘nirguṇ sant’ bhakti movements has been largely overlooked, the assumption being that these movements drew their following primarily from members of subaltern communities. Yet a close reading of these hagiographical sources reveals that merchants and scribes played a central role in shaping the theological and literary character of these movements, and in turn these movements reorganised the social and financial relationships within these mercantile communities. By focusing on such ‘middle’ groups—that is, groups that mediated intellectual, literary and economic exchanges between different spaces and institutions such as the monastery, the court and the bazaar—historians, as well as scholars of literature and religion, can gain insight into how merchant and scribal groups helped to re-form notions of the individual, community and polity in early modern North India.
The One-Party Versus Third-Party Platform Conundrum: How Can Brands Thrive?
Authors: Bei Zhiling , Gielens Katrijn
Published: July 2022

Online platforms aggregating brands, such as Amazon and Alibaba's Tmall, have emerged as powerful intermediaries for brands. Although these platforms offer unprecedented access to consumers, the platform controls this access. Thus, concerns are raised about how these platforms interfere with the brand experience and, ultimately, performance. The question of how brands can govern their platform operations more effectively thus arises. There are essentially two types of governance models: a one-party (1P) marketplace (wholesaling to the platform) and a third-party (3P) marketplace (selling directly to the consumer on the platform). However, it is unclear how 1P or 3P operations affect brand performance. To that extent, the authors study the market share implications of operations on JD.com, a 1P platform, and Tmall, a 3P platform, for almost 2,000 brands. On average, 1P operations decrease shares, whereas 3P operations lift shares. These changes depend on different brand-specific moderators. For 1P operations, share drops are more substantial for brands that are unable to elicit a trustworthy consumer relationship, when alternative brands abound and rogue-seller activities are severe in the product category. The 3P share lifts, in contrast, are more substantial for premium-priced, nonleading brands with prior direct-to-consumer experience.
Infrastructure mosaics in urban India: Sewage beyond the networked city
Authors: Oberg Angela
Published: July 2022

In this paper, I illustrate how sewage is managed beyond the networked city to create infrastructure mosaics – patchworks of interconnected infrastructures across the city characterised by variegation, fluidity and non-linearity. The purpose of this work is to develop the concept of infrastructure mosaics as a way to understand urban sewage flows in Southern cities based on the lived experience of residents, rather than on concepts developed to describe Northern cities. I begin with a brief review of how the concept of networked cities has been applied to the Global South. I then explore how sewage operates within the networked city and beyond. I finish by contextualising these ideas through the case of sewage in Agra, India. The findings from this work can help planners and policy makers across the North/South divide better understand how urban sewage operates in reality, giving decision makers insights into opportunities for improvement outside the modern infrastructural ideal.
Curing Virtue: Epicureanism and Erotic Fantasy in Machiavelli’s Mandragola
Authors: Clarke Michelle T.
Published: July 2022

Who is Lucrezia, the mysterious woman at the center of Machiavelli’s comic play Mandragola? And why is she deemed “fit to govern a kingdom”? This article revisits these questions with attention to Mandragola’s sophisticated, and often irreverent, allusions to Roman source materials. While scholars have long recognized that Mandragola draws on Roman history and drama, its sustained engagement with Lucretian and Ovidian poetry has gone largely unnoticed. In what follows, I trace these allusions and show how Machiavelli uses them to bring into view the fertility of erotic desire. Mandragola is replete with Lucretian phrases and imagery, but a close examination of these references indicates they are made playfully, and even satirically, in the style of Ovid’s Ars amatoria, a didactic elegy on the art of seduction that develops a mixed assessment of Epicurean teachings. Like Ovid, Machiavelli embraces the hedonism that motivates Epicureanism—but without accepting that happiness requires distancing ourselves from illusion. This departure allows both Ovid and Machiavelli to reassess the status of erotic desire. For Lucretius, erotic desire must be handled with extreme caution lest it entangle the mind in ruinous false beliefs and destroy the possibility of theoretical wisdom. Machiavelli, following Ovid, recommends a different course, in which happiness is achieved through the deliberate manipulation of erotic fantasy. For Machiavelli, staging erotic fantasies is an essential part of statecraft.
Predicting Public Cooperation Toward Government Actions in the Early Stages of an Influenza Pandemic in the United States: The Role of Authentic Governmental Communication and Relational Quality
Authors: Li Jo-Yun , Lee Yeunjae
Published: July 2022

During a public health crisis, government sector is considered the natural leader for overall preparedness and management efforts. Integrating the literature from public relations and public health disciplines, this study proposes a theoretical model to predict individuals’ perceptions, communicative action, as well as their behaviors to follow the governments’ instructions in the early stages of the COVID-19 outbreak in the United States. Linking relationship management factors and the framework of the situational theory of problem-solving, the findings of this study demonstrate that authentic communication and relational quality can help increase positive perceptual, attitudinal, and behavioral outcomes desired by governments regarding pandemic management. However, our findings suggested that unproductive uses of authentic governmental communication may create adverse effects on publics’ perceptions and interpretations and thus pose potential risks, particularly when a public health issue is significantly politicized. Specifically, this study found that, in the case of the COVID-19 pandemic in which the Trump administration was blamed for lack of planning and halting responses in the fight against the virus, conservatives who believe that the federal government is practicing authentic communication during the pandemic would consider the issue less important and irreverent; meanwhile, they would recognize more barriers to adopt preventive actions. Theoretical and practical implications are discussed.
Conceptualizing and Measuring Public Stigma Toward People With Prison Records
Authors: Shi Luzi , Silver Jason R. , Hickert Audrey
Published: July 2022

Public stigma toward people with prison records hinders re-entry initiatives. Although it is widely discussed in corrections, its measurement has been study specific. Based on existing literature, we develop and test a multidimensional public stigma scale. We examine the factor structure and dimensionality of the scale using a Qualtrics Panel sample of U.S. adults ( N = 1,216) and exploratory and confirmatory factor analyses, which show that 17 of the 20 proposed scale items produce a four-factor structure, including danger/distrust, dehumanization, dispositional crime attributions, and social/emotional distance. We assess construct validity by testing the relationship between public stigma and theoretical antecedents and expected support for policy outcomes. Results show that public stigma is positively related to belief in evil and racial resentment and negatively related to personal and vicarious arrest experiences. It is also positively related to support for disenfranchisement and punitive policies and negatively related to support for rehabilitative policies.