bluuebunny/crossref_metadata_2025 huggingface dataset:
Management of emergency department diversion during the COVID-19 pandemic and disaster periods
Authors: Steflovich, MSFES, EMT, NREMT Michael
Published: February 2023

Background: Recent news has shown the strain on hospital emergency departments (EDs) and emergency medical services agencies due to the surge of COVID-19; however, compared to all emergency medical service transports, is it true that the United States is seeing an increase in the frequency of diversions? In this quantitative research report, data were collected and analyzed from a national prehospital emergency medical services information system, which allowed for a comparison of the frequency of diverted ambulances, transport times, and final patient acuity of patients arriving by diverted ambulances before and during the COVID-19 pandemic. Statistical analysis was performed on data obtained from the National Emergency Medical Services Information System to compare the frequency of ambulance diversion prior to the COVID-19 disaster and during COVID-19.Findings: Analysis of data obtained from the National Emergency Medical Services Information System found that there was not a significant increase in the percentage of ambulance transports that were diverted during the COVID-19 pandemic compared to before the pandemic. However, there were significant increases in the volume of all transports and diverted transports during the COVID-19 pandemic (p < 0.01 for both measures).Conclusion: The significant increases seen in the demand for services, combined with an overall downward trend in the number of healthcare facilities, have resulted in an increase in the volume of diversions, despite the overall demand increasing as well. The COVID-19 pandemic serves as a disaster/public health crisis that is subject to the same phases compared to other types of disasters. The significant findings of this report should provide the emergency services field a big picture, understanding that the problem at hand is multifaceted, with these findings shining light on the effects of current issues between emergency services and hospital EDs.
From the publisher
Authors: DeVito, Jr Richard A.
Published: February 2023

On behalf of the Editor-in-Chief, Dr. William L. Waugh, Jr and Special Issue Editor, Dr. Attila J. Hertelendy, I would like to extend our gratitude to all of the authors who have submitted their manuscripts for consideration. Your contributions have been vital in advancing our understanding of the pandemic and its impact and have helped to shed light on a multitude of important issues related to COVID-19. Your dedication to researching and sharing your findings has been truly inspiring and has helped to make a positive impact in the world.
COVID-19 pandemic 3 years in: We are NOT ready for the next pandemic!
Authors: Hertelendy, PhD Attila J. , Waugh, Jr, PhD William L.
Published: February 2023

On December 29, 2019, four workers from the Huanan Seafood Wholesale Market, in Wuhan, China were admitted to hospital with pneumonia. By January 7, 2020, the National Institute of Communicable Disease Control and Prevention (Chinese Center for Disease Control and Prevention) had announced that they had isolated a novel coronavirus (CoV) from patients in Wuhan. Little did the world know that Wuhan would become ground zero for what would become one of the most significant health crises to affect the globe in recent memory. On January 30, 2020, the World Health Organization (WHO) declared a Public Health Emergency (PHE) of International Concern. The first United States (US) case of the CoV occurred in Washington State on January 21, 2020. In late January 2020, the US declared a PHE due to the coronavirus outbreak. The announcement came days after the WHO declared a Global Health Emergency as more than 9,800 cases of the virus and more than 200 deaths had been confirmed worldwide.3 On March 11, 2020, the WHO announced to the world that SARSCoV- 2 (COVID-19) was a global pandemic.
Salir del clóset democrático
Authors: Proceso
Published: February 2023

No hay resúmenes disponibles.

Proceso, Año 3, No. 104, 2022: 5-6.
Con la reelección se consuma la dictadura
Authors: Proceso
Published: February 2023

No hay resúmenes disponibles.

Proceso, Año 3, No. 105, 2022: 5-7.
Hechos destacados de la semana 22 al 28 de septiembre
Authors: Proceso
Published: February 2023

No hay resúmenes disponibles.

Proceso, Año 3, No. 105, 2022: 12-16.
beneficios de servir al régimen
Authors: Deras Roberto
Published: February 2023

No hay resúmenes disponibles.

Proceso, Año 3, No. 106, 2022: 8-9.
etapas del régimen híbrido
Authors: Proceso
Published: February 2023

No hay resúmenes disponibles.

Proceso, Año 3, No. 114, 2022: 5-6.
CLINICAL AND MORPHOLOGICAL CHARACTERISTIC METABOLIZM CHANGES AT THE DIABETES
Authors: Turchenko N. M. , Golubev O. A.
Published: February 2023

In the review of the literature the modern data about clinical and pathomorphological characteristics of infringements of an exchange are submitted at a diabetes. Are offered new perspective pathomorphological markers metabolism changes which use can bring in the essential contribution to specification of parts morphogenesis a diabetes.
Dependance of children’s health status, environmental and life conditions
Authors: Dorofeyeva S. M.
Published: February 2023

The survey results of combined influence of environmental and life conditions to health status of school aged children living in large industrial city are present to. The influence of negative ecological conditions intensified by defects of nutrition ration and meals order, combined with low physical activity and psycho-emotional pressure is a sum total of survey. As a result of such influence the physical evolution problems, increase of prevalence of diseases of respiratory, digestive, endocrine and genitourinary systems, diseases of the skin were found out.
INFLAMMATORY BOWEL DISEASES: MODERN VIEW OF DIAGNOSTICS PROBLEMS
Authors: Mikhailova E. I. , Danchenko M. N.
Published: February 2023

Inflammatory bowel diseases are characterised by chronic, relapsing intestinal inflammation. This article sets out the clinical features and diagnosis of ulcerative colitis and Crohn's disease.
FACTORS OF PROGNOSIS OF THE CANCER OF RECTUM II-III STADIUM AFTER PREOPERATIVE RADIATION THERAPY
Authors: Achinovich S. L. , Nadierov E. A. , Golubev O. A.
Published: February 2023

We researched factors of prognosis of the cancer of rectum 2-3 stadium after preoperative radiation therapy. Correlative dependencies between apart prognostic rates which characterize complications of the main disease (development of recidives, production of metastasis) were estimated. Prognostic importance in quality of factors, negatively influencing on the prognosis of the disease was revealed. Tumor size, kind of growth and invasive growth into intestinal wall, quantity of lymphatic nodes with metastasis, high level of Ki-67, p53 expression, stage of malignancy, conditions of tumor edge and intravascular invasion occurred to be the most important. The results, we got, can be used in evaluation of the stage of risk of postoperative complications development after carried preoperative radiation therapy.
CURRENT STATE AND PROSPECT OF INTERVENTIONAL METHODS OF DIAGNOSTICS AND TREATMENT OF CORONARY VASOSPASM
Authors: Gorokhovsky S. Y.
Published: February 2023

Currently coronary arteriography is widely used to establish the presence or absence of coronary stenoses, define therapeutic options, and determine prognosis in patients with symptoms or signs of ischemic coronary artery disease. Vasospastic angina indicates a form of angina caused by coronary artery spasm. The article reviews the most common difficulties and prospect of application of contemporary methods of diagnostics and treatment to find a solution of the task. The important tendency is development of percutaneous coronary interventions in treatment of coronary vasospasm.
ASSESSMENT OF LIFE QUALITY IN COMPLEX ESTIMATION CONDITION OF COMPENSATION IN TYPE 1 DIABETES
Authors: Rusalenko M. G.
Published: February 2023

The attitude of patients with diabetes Type 1 to treatment which essentially affects clinical course, is formed as a result of influence of many psychological and social factors. Achievement and long maintenance of compensation at diabetes is impossible without active participation of the patient in medical process. Detection of psychological features in a complex with definition of metabolic infringements is directed on complete representation about adaptive opportunities and defense mechanisms of patients with the purpose of development more adequate psychosomatic approaches. Quality of life (QOL) - it is satisfaction degree of man with his physical, mental and social condition. QOL on influence of remedial measures and reflecting subjective judgment of condition as a result of treatment or influences of illness.
HYGIENIC FUNDAMENTALS OF PRIMARY METEO-DEPENDENT DISEASES PREVENTION
Authors: Kartasheva N. V. , Bortnovsky V. N.
Published: February 2023

The present study describes the hygienic fundamentals of meteo-dependent diseases prevention considering climatic zones of the Republic of Belarus. Climate and weather, health of the population are the complex issue.
ALCOHOL AND CARDIOVASCULAR MORTALITY ARE THE POPULATION LEVEL OF INTERRELATION
Authors: Razvodovski U. E.
Published: February 2023

This article deal with comparative analysis of trends in cardiovascular and alcohol poisoning mortality rates in Russia in 1956-2005. The results of the time series analysis suggest a close relationship between the cardiovascular mortality and fatal alcohol poisoning rate at the population level. This study supports the hypothesis that an intoxication-oriented drinking pattern (binge drinking) is a risk factor for cardiovascular mortality.
Ionizing radiation and leukemia in relation to the incidence in children of Belarus after the Chernobyl accident
Authors: Savva N. N. , Hoshi M. . , Aleinikova O. V.
Published: February 2023

The article contains the scientific facts regarding the radiogenic leukemia risks in children after the exposure of low doses ionizing radiation, as well as the results of the main completed epidemiological childhood leukemia studies in Belarus after the Chernobyl accident, and a discussion of the necessity of further researches taking into account the recommendations of the Chernobyl Forum and World Health Organization.
CHANGES OF ENERGY METABOLISM IN SMALL INTESTINE ON THE TENTH DAY AFTER GAMMA IRRADIATION
Authors: Jaskova N. S.
Published: February 2023

In the article the results of experimental research of external low-doze irradiation influence on parameters of tissue respiration and oxidative phosphorylation in small intestine are described. There is an assumption, that the one of the most vulnerable cellular organelle is mitochondria. Ten days after the irradiation the significant changes in respiratory activity were observed on both endogenous and exogenous substrates, which confirm the important role of glutamate in the energy production of the small intestine.
USE OF THE PROCALCITONIN TEST FOR DIAGNOSTICS OF INFECTED PANCREATIC NECROSIS
Authors: Mauda Shadi L. A. , Litvin A. A. , Jarikov O. G. , Senchuk G. A.
Published: February 2023

The significance of plasma procalcitonin concentration for the differential of sterile and infected pancreatic necrosis was evaluated. Twenty-five patients with acute severe pancreatitis were examined. Plasma procalcitonin concentrations were notably increased in patients with infected pancreatic necrosis. These data indicate that measurement of procalcitonin concentration is the optimal laboratory test for the differential diagnosis of sterile and infected pancreatic necrosis.
DIAGNOSTIC VALUE OF THE ULTRASOUND ANGIOGRAPHY FOR THE LOWER LIMBS DEEP VEINS VALVES ASSAY
Authors: Sushkov S. A.
Published: February 2023

Diagnostic value of duplex angiography for deep veins valve investigation been assessed. Retrograde phlebography (femoral or popliteal) have been choozen as referent method («gold standard»). The following criteria were took for account: accuracy, sensivity, specific and prognostic value of the positive and negative result. Figures of the duplex angiography stable charecteristics (sensivity and specific) indicates that the method may be useful for estimating femoral or popliteal veins valves condition. For the both segments predictive value of the negative result was higher then the positive. The analisis shows ability of the colour Doppler ultrasonography to be used as a screening and monitor method, because it leads to indicate most of the valve pathology among the varicose diesis patients and allow to estimate efficacy of the correction treatment. It is also may be used as a step in diagnostic for detecting the patients requiring deeper and more expensive invasive examination.
INTRAOPERATIVE ULTRASOUND DIAGNOSTICS OF INTRACEREBRAL BLEEDINGS
Authors: Tsitko E. L. , Govrushko O. S. , Litvin A. A. , Yurgel A. V.
Published: February 2023

The paper presents the results of brain intraoperative ultrasound examination.Revealed ultrasound characteristics of intracerebral haematomas at acute, subacute and chronic stages contention with the data of cerebrum computer tomography. There was shown the diagnostic value of intraoperative ultrasound diagnostics at patients with intracerebral bleedings.
LUBRICATING ABILITY OF SYNOVIAL FLUID SUBSTITUTES ON THE BASE OF BLOOD SERUM
Authors: Nikolaev V. I. , Kalodich G. V.
Published: February 2023

A row of synovial fluid substitutes on a base of blood serum was tested by lubricating ability criterion with a help of a friction gage of pendulum type. Detected that a coefficient of pair friction, modeling a metal-polymeric implant joint, was changing during lubrication under the influence of magnetic field. The regularities of such changes depend on the correlation and characters of autoserum modifiers action. It was marked a practical meaning of the tribological analysis compositions of artificial synovial fluid for local joint therapy
ONCE Again to the issue of fluorosis in Belarus
Authors: Popruzhenko T. N. , Popruzhenko T. V.
Published: February 2023

A nidus of fluorosis was revealed in Mogilev region, the reason is high content of fluoride in local water ([F] = 5,5mg/l). The source of water lies 169m deep, the water supplies the system that has been serving one of the village streets for the last 29 years. All of the 12 teenagers living in the street since early childhood have teeth impacted with fluorosis, from mild (45,5%) to moderate (36,4%) to greater forms (18,2%). The prevalence of dental caries among the teenagers is significantly lower than among those living in fluoride deficit areas. Their day urine contains a very high level of F ([F] = 4,3mg/l), which should be interpreted as a marker of a high actual F intake. Changing the water source was suggested, as well as special activities to rehabilitate inhabitants’ health condition, and temporal limitation in use of F-containing caries prevention applications.
AFM ELASTOGRAPHY IN A NEW BIO-MEDICAL INVESTIGATIO
Authors: Kuznetsova T. G. , Starodubtseva M. N.
Published: February 2023

The paper reviews recent atomic force microscopy findings in the area of cell nanomechanics and determines the perspectives of elastography as a new bio-medical technology.
MODERN DIAGNOSTICS POSSIBILITIES OF INFECTED PANCREATIC NECROSIS (literature review)
Authors: Litvin A. A. , Mauda Shadi L. A.
Published: February 2023

The literature review is devoted a vital topic of emergency surgery. It is diagnostics of infected pancreatic necrosis. Infectious complications of an acute pancreatitis are a principal cause of lethal outcomes. Timely diagnostics of the infected pancreatic necrosis allows changing medical tactics. Authors have carried out the analysis of modern methods of diagnostics of a pancreatic infection. Now the most informative methods are laboratory monitoring, procalcitonin test, fine-needle aspiration biopsy, CT-scan, etc.
ETIOLOGY AND PATHOGENESIS OF DISTURBED LIPIDIC METABOLISM OF PATIENTS WITH NUTRITIVE OBESITY
Authors: Drobyshevskaya V. A. , Latysheva V. A.
Published: February 2023

In any time a lot of hypothesis were suggested for the explanation of nature nutritive obesity. Some of them don’t lose their urgency, the discussions of others can be of interest just in historical aspect. In this work there were represented only modern judgements at etiopathogenesis of mutritive obesity connected with it metabolic syndrome.
ROLE OF ACTIVE FORMS OF OXYGEN IN DAMAGE HEPATOCYTES AT INFECTIOUS-INFLAMMATORY PROCESSES
Authors: Palkovsky O. L.
Published: February 2023

At an infectious-inflammatory pathology increase of activity free-radical processes is observed. Besides active forms of oxygen in oxidizing processes participate as well metabolites of oxide nitrogen which formation depends from перекисных processes. In work expressiveness free-radical processes is investigated at an infectious-inflammatory pathology and changes of some parameters of a homeostasis on a background of oxidizing stress. Research has shown presence of biochemical attributes of damage of cells of a liver, on a background infectious-inflammatory to a pathology which are directly not mentioning a liver.
USE OF METHODS OF THE FACTORIAL ANALYSIS FOR REVEALING THE GENERALIZING CHARACTERISTICS, ALLOWING TO ESTIMATE THE VARIATION OF THE AVERAGE ANNUAL DOZE OF THE INTERNAL IRRADIATION
Authors: Drozdou D. N. , Averin V. S.
Published: February 2023

In work the approach for an estimation of the importance of this or that criterion in formation of a mid-annual doze of an internal irradiation of inhabitants of the rural settlements located in territory of radioactive pollution is offered.
THE ANALYSIS OF CLINICAL AND X-RAY FOR THE TRAUMATIC STENOSIS OF THE LOWER CERVICAL COLUMN
Authors: Kirilenko S. I. , Beleckij A. V. , Petrenko A. M.
Published: February 2023

The analysis of a correlation of a degree traumatic stenosis of the backboned canal is fulfilled at damages the lower cervical column in the groups with the different degree of neurological compensation and the basic rates spinal injuries, which use in the standard classifications by force of correlation matrix construction.
THYROID STATUS PARAMETERS AT CHILDREN’S EXPOSED TO IODINE RADIONUCLIDE’S DURING IN UTERO DEVELOPMENT
Authors: Panasiuk G. D. , Nadyrov A. A. , Rozko A. V.
Published: February 2023

There was analyzed the status of thyroid system parameters and frequency of individual values prevalence of antibody - carriage at children’s born in May 1986 - February 1987 exposed to iodine radio nuclides in intra-uterine period of development from 4 regions of Gomel Oblast (Gomel, Loev, Rechitsa, Khoiniki). At comparison of prevalence frequency of antibody - carriage to microsomal antigen among young men and girls it is shown that the given parameter statistically significantly is defined more often in the basic group at comparison with the conditional control; also there was marked statistically significant difference in Gomel region among young men and girls. The parameters of thyroid system status (thyrotropic hormone, free thyroxin) at children’s exposed to irradiation during intra-uterine development are within physiological values.
USE OF DATA OF EVIDENCE BASED MEDICINE IN CLINICAL PRACTICE (literature review)
Authors: Kalinin A. L. , Litvin A. A. , Trizna N. M.
Published: February 2023

The purpose of article is the review of principles of evidence based medicine and the meta-analysis. A prominent aspect of evidence based medicine is definition of degree of reliability of the information. Quantitative association of the given various clinical researches by means of the meta-analysis allows to receive results which cannot be received from separate clinical researches. Reading and studying of systematic reviews and results of the meta-analysis allows to be guided more effectively in a considerable quantity of published articles.
STRUCTURE OF AN ACUTE MYOCARDIAL INFARCTION, AGE AND SEXUAL FEATURES OF COURSE AND DEATH RATE AT HOSPITAL STAGE OF TREATMENT
Authors: Vasilevich N. V.
Published: February 2023

The structure, dynamics of development of an acute myocardial infarction depending on the sex, age, terms of receipt to hospital, gravity of injury of myocardium at a hospital stage of treatment were tracked.
ESTIMATION OF TYPE 1 DIABETES COMPENSATION BY RESULTS OF GLUCOSE LONG MONITORING
Authors: Makhlina E. .
Published: February 2023

Recently in diabetology there were started actively implementing new modern technologies. One of such directions in continuous glucose monitoring system (CGMS). The purpose of the present work is revealing of hypoglycemia fluctuations during the day by CGMS, detection of frequency and duration of hypoglycemic reactions and registration of post hypoglycemic hyperglycemias. The provided data analysis has shown that the period of hyperglycemia made up the basic period of time not depending on patients age. The given fact is caused by chronic insulin overdose due to latent hypoglycemias and a syndrome of the damaged glycemia counter-regulation.
Influence EXTRAVENOS LASER irradiation of blood As way of correction neuropsychological infringements At patients with chronic cerebrovascular insufficiency
Authors: Halynouskaja N. V. , Latyschewa V. Y. , Emeshkov L. A. , Usava N. N. , Salocha T. A. , Shaparava O. V.
Published: February 2023

The aim of the study was the investigation of influence extravenous laser irradiation of blood on a condition neuropsychological and the vegetative status at patients with chronic cerebrovascular insufficiency for what 22 patients in the age from 64 till 84 years have been surveyed. It was shown after the lead rate of therapy hyperactivation of vegetative security and some improvement performance neurodynamic tests at deterioration of parameters of attention and working capacity.
LABORATORY AND CLINICAL CHANGES OF ANTIRETROVIRAL THERAPY
Authors: Mironenka T. M. , Krasavtsev E. L. , Kozorez E. I. , Kaznatcheeva E. P.
Published: February 2023

In the article we can determine changes of parameters of the general and biochemical analyses of blood, also me can find clinical displays at patients on the various schemes of antiretroviral therapy applied to treatment of a HIV-infected in the Gomel regional infectious hospital are presented. It is revealed, that at the HIV-infected receiving various schemes of antiretroviral therapy, in 1-6 months of treatment the individual clinically expressed by-effects leading a cancelling or change of the scheme of antiretroviral therapy were observed. On the scheme: combivir + stocrin leading change were registered hematologic changes (heavy anemia) in 11, 8% of cases therefore scheme of therapy was changed. At the patients was on the scheme combivir +virasept, in 1 month from the beginning of treatment the maintenance of the general bilirubin in whey of blood authentically increased. Among the patients received stocrin + epivir + zerit, in 1 month from the beginning of treatment activity α- -amylase authentically increased. At the majority of patients with revealed аnti-HCVtot with presence of biochemical activity on a background of treatment parameters ALT were normalized.
STRUCTURE ORGANIZATION OF THE AREA OF ORIFICES OF CAVA VEINS IN THE HUMAN EMBRYOGENESIS
Authors: Saharchuk T. V.
Published: February 2023

The of development of the area of orifices of cava veins have been investigated on serial cuts taken from 133 human embryos at the age of 4-8 weeks of intra-uterine development. It is has been established, that the right common cardinal vein (RCCV), left common cardinal vein (LCCV) and inferior vena cava initially open in a sinus venosus of the heart. Their orifices locate very close from each other. In process of growth of the heart the orifices of these veins gradually remove from each other that testify to gradual embedding the wall of a sinus in the wall of the right auricle and the above mentioned veins are open in the cavity of the right auricle. RCCV and the right horn of a sinus form superior vena cava, and LCCV (it’s distal portion) and the left horn - a coronal sine of heart. At the entry of a primary auricle there is the venous valve consisting of the right and left shutters. It prevents from a retrograde blood flow in a sinus venosus and afferent vessels. In due course the left shutter is reduced . The valve of the inferior vena cava (Eustahii) and the valve of the sinus coronarii (Thebesii) are formed from the right one. Also it is revealed, that in embryogenesis the layings of the future myocardial constrictors of cava veins are formed.
Features of Morphogenesis of the esophago-gastric junction of human in the intra-uterine period of development
Authors: Shestakovich K. N.
Published: February 2023

Features of dynamics of morphogenesis of the esophago-gastric junction of human in the intra-uterine period of development are established: 1) During of morphogenesis of the esophago-gastric junction passes a number of consecutive stages: a stage of a formation; the stage has begun histogenesis; a stage of physiological atresia; a stage of canalization and a stage of end histogenesis; 2) By the end of 10 weeks embryogenesis the epithelium layers of a distal department of esophagus it is a ciliary epithelium.
VARIABILITY OF A STRUCTURE, TOPOGRAPHY AND MORPHOMETRICAL PARAMETERS PECULIARITIES OF THE VESSELS OF THE ANTERIOR PARTS OF IRCLE OF WILLIS IN HUMAN
Authors: Pivchenko P. G. , Trushel N. A.
Published: February 2023

As a result of research variations of a structure, topography and morphometrical parameters of the vessels of anterior parts of circle of Willis of brain are revealed depending on the constitution of skull and sex. By all types of constitution of skull the classical variant of structure of the anterior parts of circle of Willis of brain discovered in 75-87% events; in 13-25% events - its variants, which characterize in large various of anatomy and morphometrical parameters. In women the diameter of the anterior artery of the brain is larger then in men on 22,6% events. Different variants of structure of the anterior artery of brain are discovered in brachiocephals most often. Мorphometrical parameters of the anterior artery of brain in brachiocephals are larger then mesocephals and dolichocephals
DIRECT RESULTS OF ALLOHERNIOPLASTY POSTOPERATIVE VENTRAL HERNIAS WITH USING OF CURRENT TECHNOLOGY
Authors: Meloyan A. K. , Bogdanovich V. B.
Published: February 2023

The work is based on study and analysis the direct results of surgical treatment 117 patients with postoperative ventral hernias to whom have been made allohernioplasty by the on lay method. The structure of early specific postoperative complications have been studied and their comparative analysis of tissue dissection method have been led. The investigation results showed that by using a method of ultrasonic dissection the amount of the complications was in 3,4 times less in comparison with the classic method of using a high-frequency coagulator. Moreover such complications as haematoma, ischemic necrosis of skin and subcutaneous cellular tissue but also infiltrations (in patients with primary ventral hernias) there were not met that was evidence of reliable hemostatic effect of the ultrasonic generator, «atraumatic» tissue dissection and positive literal it’s influence upon the surrounding tissues.
ABDOMINAL COMPARTMENT SYNDROME IN PATIENTS WITH ACUTE PANCREATITIS
Authors: Litvin A. A. , Al-Daosari A. O. , Mauda Shadi L. A. , Senchuk G. A. , Ali Abdulaziz A. M.
Published: February 2023

Hospital mortality in patients with severe acute pancreatitis remains high. Some of these patients develop increased intra-abdominal pressure which may contribute to organ dysfunction. The review explores the challenges in diagnosis, pathophysiology, and recent concepts in the treatment of abdominal compartment syndrome in patients with acute pancreatitis.
DIAGNOSTICS ALGORITHM OF IRON DYSBOLISM IN PATIENTS WITH CHRONIC DIFFUSIVE LIVER DESEASE
Authors: Bogush L. S.
Published: February 2023

Iron metabolism disorders are frequent in chronic diffuse liver diseases (CLD). Aims - to determine the peculiarities iron metabolism in patients with CLD and to develop diagnostic algorithm. Methods - complex clinical and morphologic investigation the iron metabolism in 167 clinical and 142 sectional cases of different CLD. Results - Laboratory signs of iron deficiency was disclosed in 26 (15,5%) and signs iron overload (IO) was determined in 35 (20,9%) CLD patients (n = 167). A liver hemosiderosis was discovered in 66 (46,5%) sectional cases CLD (n = 142). A HFE gene mutations was revealed in 11 (36,7%) of 30 CLD patients with IO. Conclusions - To order all CLD patients the iron metabolism disorders screening. Diagnostic algorithm was developed due to investigation results and modern requirements. Our algorithm provides the differentiated approach to diagnostic iron metabolism disorders in CLD patients.
THE DEVELOPMENT OF rELAPSE REGULARITY OF STOMACH CANCER SPREAD LOCALY
Authors: Al-Yahairi A. K.
Published: February 2023

Conformities to the law of development relapses and metastases are analysed at 110 patients by the locally widespread gastric cancer (LWGC) after surgical and complex treatment. The basic display of generalization the tumour was peritoneal dissemination. Lymhatic metastasis was observed also often enough, in most cases combining with peritoneal dissemination. Loca-gional a relapse often comes to light at patients with LWGC IV stage (T4N1-3M0), he arose up for 42 % patients. Local relapse at patients with LWGC stage IV more frequent than all develops the stage (T4N1-3M0) in area of esophago-enterostomy in 67 % (8/12) patients after implementation of gastrectomy. Conducting adjuvant chemio-radiotherapy (ACRT) at that patients provides the high degree of local control the tumour process, appearance of local relapse for these patients was not observed, then, as in the comparison groups it was exposed at 12 % (5/41) and 21 % (7/33) patients accordingly from the studied localization of relapse.
POSSIBILITIES OF FORECASTING OF CHILD IDIOPATIC THROMBOCYTOPENIC PURPURA VARIANT
Authors: Hoduleva S. A. , Romashevskaya I. P.
Published: February 2023

The clinico-immunological survey of 109 children at the age of from 2 months to 15 years suffered from idiopathic thrombocytopenic purpura (ITP) has been conducted. In the course of verification of the diagnosis, in order to evaluate trombocytopoiesis, the method of flow cytometry was used to detect the level of young forms of platelets marked with thiazole-orange. The misbalance of immune status at child ITP was detected which is characterized by T-cell link suppression (CD3+) due to T-helpers (CD4+) and T-active lymphocytes (CD3+HLA-DR+) and excessive activation of B-cell link (CD19+). Acute ITP presented in 65 % of cases, chronical one - in 35 %.Possible prognostic clinico-immunological criteria of ITP variant have been detected.
THE PECULIAR INDICES OF TYMPANOMETRY DURING CHILDREN'S EXUDATIVE MIDDLE OTITIS
Authors: Hanfar Adnan , Sitnikov V. P.
Published: February 2023

With a help of objective method that is tympanometry in the treatment process, the inspection results of 180 children suffering from exudative middle otitis (EMO) are presented in the work. Presented the various variants of B type tympanometry curves, analysed mutual relations a tympanogram with the indices of conventional audiometry and a level of exudation in barrel.
CAUSES OF ANGINA WITH NORMAL OR NONOBSTRUCTIVE CORONARY ARTERIES
Authors: Gorokhovsky S. Y. , Anichkin V. V.
Published: February 2023

Up to 20 percent of patients with anginal chest pain, the coronary angiogram, usually obtained because of «positive» findings on one or more noninvasive tests, does not show clinically significant narrowing of the vessel lumen. The most common causes of these conditions such as variant angina, X-syndrome, gastrointestinal disorders and others are systematizing in this article. The practical algorithm for management of patients with symptoms and nonobstructive coronary artery disease is presented.
ESTIMATION OF SAFETY OF THE WATER OBJECTS USED IN RECREATIONAL PURPOSES FOR THE HEALTH OF POPULATION: NEW APPROACHES
Authors: Kljuchenovich V. I. , Klimovich S. V. , Treshkova T. S. , Bortnovsky V. N.
Published: February 2023

Today is actual the problem of development of the unified system of an estimation of natural-recreational potential of the water objects on the basis of quantitative and qualitative standard of potential opportunities of superficial reservoirs and a hygienic substantiation of perspective methods of disinfecting of the sewage alternative to chlorination. The instruction called «Criteria of safety of the water objects of the Republic of Belarus used in the recreational purposes for the health of population» is developed. The catalogue of modern methods of disinfecting of sewage is being given prove.
MODERN SURGERY FOR VARICOSE VEINS OF LOWER EXTREMITIES
Authors: Lyzikov A. N. , Skuratov A. G. , Osipov B. B.
Published: February 2023

In the article the modern pathogenetically proved technologies in treatment for varicose veins of the lower extremities, both classical, and innovative are generalised. Advantages and disadvantages of each method are specified. Also results of treatment of patients with varicose veins of the lower extremities in the Center low-invasive and reconstructive surgery on the basis of the Gomel central city hospital are presented. It is shown, that introduction of innovative technologies in surgery for varicose veins of the lower extremities is of great importance as in the medical and social plan.
MAIN LINES FOR ACUPUNCTURE TREATMENT EFFECTIVENESS IN REHABILITATION OF PATIENTS WITH TRAUMATIC NEURITIS OF FACIAL NERVE
Authors: Pohodenko-Chudakova I. O.
Published: February 2023

Review contains information about the quantity, clinico-funtional methods of examinations, modern principles of treatment and rehabilitation for patients with mentioned above diseases. So, we could conclude that is necessary to make further study of acupuncture application included in complex of treatment and rehabilitation procedures using its bases for elaboration of new tests for appreciation of treatment effectiveness when treating patients with traumatic neuritis of facial nerve.
RECURRENCE-DANGEROUS CLINICAL CONDITION IN ALCOHOL-ADDICTS AT EARLY TERAPEUTIC REMISSION
Authors: Skvira I. M.
Published: February 2023

The data about on display relapse-dangerous clinical situations (depressions and others) of the alcohol depended patients in the first 6 months remission time (F10.200) are presented in this articles. The recommendations are formulated on early diagnostics and address therapy of the patients with alcoholic dependence during treatment and rehabilitation.
TRAUMATIC MODEL OF ACUTE AND CHRONIC PANCREATITIS
Authors: Doroshkevich S. V. , Doroshkevich E. Yu.
Published: February 2023

Surgical methods of modeling of cysts of the acute and chronic pancreases are generalized, the critical estimation is given. The original traumatic way of reproduction of the experimental pancreas, where the basis is the local cold influence on the pancreas of white rat with the help of cryosurgical complex KCH 3A/B is offered. The work was done with the observance of the rules stipulated by the European Commission on supervision of carrying out laboratory and other experiments with participation of experimental animals of different kinds. Cooling was carried out intraoperatively, by the direct contact of the cryosurgical tip with the tissue of the pancreas. The features of morphological changes, depending on the cooling temperature are established. The offered traumatic model of acute and chronic pancreas gives an opportunity to study mechanisms of the origin of the pathology and to approve the ways of the treatment.
HAIR STRUCTURE IN BELARUSSIAN POPULATION
Authors: Malenchenko A. F. , Bajhanova N. N. , Jhuk I. V. , Sushko S. N. , Bortnovsky V. N. , Dorofeyeva S. M.
Published: February 2023

This article contains the research information on Byelorussian inhabitants hair element structure. Some elements concentration in Byelorussian inhabitants hair is same as in European countries and other World continents. This fact take place in respect of such elements as Na, Zn, Fe, Ag, Cr and La. Concentrations of As, Mg, Sm, and W in Byelorussian inhabitants hair are within published average World levels. It is necessity of additional epidemiological investigation to account for high concentrations of Pb and Mn at hair of inhabitants of Narovlia town.
SYMPTOMATIC HYPERTENSIONS AT PRIMARY HIPERALDOSTERONISM
Authors: Kudlasevich S. V. , Rusalenko M. G. , Rozko A. V. , Mokhort T. V.
Published: February 2023

The problem of symptomatic hypertensions at primary hiperaldosteronism continues to be urgent and becomes more and more important for the clinicians. Present-day data on the clinical picture, differential diagnostics and treatment methods of the disease are presented in the article.
STATE OF CARDIOVASCULAR AND VEGETATIVE NERVOUS SYSTEM IN CHANGE OF CLIMATIC-WEATHER CONDITIONS
Authors: Rudnitskaya A. S.
Published: February 2023

Work of heart depends on climatic-weather conditions. The initial vegetative tone and vegetative reactance at many children.
FORMATION OF ENDOCRINE REGULATION AND ORGANOGENESIS PROCESSES IN A HUMAN EMBRYO
Authors: Artishevsky A. A. , Kravtsova I. L.
Published: February 2023

The processes of rudiments, differentiation, morphogenesis, functional activity in adrenal glands and the small intestine have been retraced during the research work. The correlation between information indicators of the components of the adrenal glands and the endocrine apparatus of the small intestine has been analyzed. The dynamics of the correlative structure of the mentioned organs involving the change of value, strength and direction amend the factors in the biosystem has been revealed. The cause-relation has been introduced between endocrine apparatus of diffuse and integrated endocrine systems
MALNUTRITION: VERIFICATION, LABORATORY AND ANTHROPOMETRIC METHODS OF ASSESMENT
Authors: Vasilevskaya S. A. , Marahovsky U. H. , Kalachik V. P.
Published: February 2023

Malnutrition is common in chronic and acute gastrointestinal disease affecting both morbidity and mortality. Quality of life is generally low in benign gastrointestinal disease and is further reduced in patients who are classified as malnourished. There are a lot of difficulties for diagnosing and appropriate assessment of patients with this malnutrition. This article dedicated to the current issues such as: screening methods and ways of correction and care of this syndrome.
SPECIFIC FEATURES OF THE CONSTITUTION TYPE AT THE PEOPLE SUFFERING FROM THE DIABETES OF THE FIRST TYPE
Authors: Senko V. I. , Okolokulak E. S. , Sidorovich S. A.
Published: February 2023

The values of some anthopometrical indicators in sick of the diabetes of the first type are presented in article. The somatotypes and weight body index of the patients are defined on basis of it. The analysis of data shows the mentioned above indicators essentially differ from each other in different age groups.
CHANGES OF SOME PHERIFIRIC BLOOD OF RATS PARAMETERS AT ETHYLENE GLУCOLE INTOXICATION
Authors: Zhykova A. A. , Ovseyuk U. A.
Published: February 2023

In the acute experiments carried out on white not purebred male rats it was revealed that the characteristic features of ethylene glуcole intoxication are: neutrophilic leukocytosis, decreasing of hemoglobin amount, polychromatophilia and poikilocytosis.
APPROACHES TO SURGICAL TREATMENT OF PATIENTS WITH CHRONIC ENDOCRINE THYROID PATHOLOGY
Authors: Vasyuhina I. A. , Snitsarenko E. N. , Chernova N. F. , Zekenova K. K.
Published: February 2023

We studied 174 operated patients with thyroid pathology. We show that the most frequent reason of diffuse toxic goiter relapse is inadequate extent of surgical intervention. We defined the period of treatment duration by preparations suppressing the function of thyroid gland at diffuse toxic goiter.
REPRODUCTION FUNCTION OF RATS AT INTRODUCTION OF LIPOPOLYSACCHARIDE
Authors: Milosh T. S. , Maksimovich N. E.
Published: February 2023

On 155 pregnancy rats with intramuscular introduction of E. сoli lipopolysaccharides, «Sigma» during pregnancy determinence distutbances reproduction function, dependent from dose of lipopolysaccharides and the period pregnancy.
INFLUENCE OF ULTRASOUND ON THE ARTERIAL SIDE DAMAGE DEPENDING ON THE HEAD OF THE WAVE GUIDE STRUCTURE
Authors: Adzerikho I. E. , Yafimava N. N. , Doroshenko R. V.
Published: February 2023

The aim of the study: to study the influence of various ultrasound parameters on a damage rate of an arterial side depending on a head of a wave guide structure in vivo. It is shown, that the damage rate of a vascular side increases with the growth of intensity of ultrasonic influence and depends on a head of a wave guide structure. Porosity in a range from 15 to 45 % does not influence on a damage rate of a vascular side.
MODEL OF THE ORGANIZATION OF RENDERING OF THE TREATMENT AND PROPHYLACTIC HELP TO THE POPULATION WITH ANDROGEN DEFICIENCY
Authors: Vasilkova O. N. , Sharshakova T. M. , Mokhort T. V.
Published: February 2023

Androgen deficiency in the aging male has become a topic of increasing interest and debate throughout the world. The prevalence of androgen deficiency in the aging male population is difficult to estimate due to the heterogeneity of the studied populations, the differing methods of estimating testosterone levels (total, free estimates) and the lack of consistency of nominal values for defining biochemical hypoandrogenism. The problem of androgen deficiency in men with diabetes type 2 is very actually now. Investigation and treatment androgen deficiency allow not only prevent diabetes type 2, but also have a good control of diabetes. This condition of problem leads to organization of andrology services, including questions of early diagnostics of sexual dysfunction in men with androgen deficiency.
CARDIOVASCULAR AND CENTRAL NEURAL SYSTEM`S DISORDERS AT HYPOTHYROIDISM IN THE ELDERLY
Authors: Ukla A. A.
Published: February 2023

There are the hormonal and metabolic disorders during the elderly of organism. The most important of them are the thyroid dysfunctions. Hypothyroidism is difficult to diagnose in old age, because it has many clinical «masks». But undiagnosed hypothyroidism leads to degenerative changes in cardiovascular system and central neural system, exceeding early elderly and human social disadaptation. That’s why preliminary diagnostic and adequate correction of hypothyroidism can prolong active life in elderly.
THE DYNAMICS OF A DEATH RATE AMONG PATIENTS WITH DISEASES OF CIRCULATORY SYSTEM INGOMEL REGION IN 2003-2007
Authors: Lopatina A. L. , Dorofeev V. M. , Sharshakova T. M.
Published: February 2023

An analysis of the death-rate was performed in 2003-2007 for the purpose of revealing the consistent patterns in the dynamics of the reasons of mortality from diseases of the circulatory system among the population of Gomel Region. For the last 5 years the greatest rate of mortality among the population of Gomel Region was registered in the year 2005 - 55,7 %, in 2007 this rate was the lowest.
MODERN APPROACHES IN TREATMENT OF PATIENTS OF MULTIPLE MYELOMES (references review)
Authors: Iskrov I. A.
Published: February 2023

Multiple myelomes (MM) is the B-cellular tumor which is characterized by accumulation of plasmatic cells in bone morrow.
FLUORESCENCE OF TEETH AND FILLING MATERIALS
Authors: Novak N. V.
Published: February 2023

The results of scientific research concerning fluorescence of patients teeth (of junior and older age groups) are given in the article. Also there is a data concerning filling materials of different manufactures and their comparative characteristic.
The algorithms of diagnostics and treatment of adrenal gland incidentalom
Authors: Bogdanovich V. B. , Shebushev N. G. , Rozhko A. V. , Bereschenko V. V.
Published: February 2023

According to the data of the most authors, the number of patients with detected adrenal gland incidentalom proliferates in geometric progression every year. In the article the present-day methods of diagnostics, differentially diagnostic algorithms, tactic approaches and also the methods of treatment for accidentally detected tumor of adrenal gland have been given.
THE CASE OF THE SUPERVISION OF PATIENT SUFFERRING MIXED DEMENTIA WITH ALZHEIMER’S DISEASE
Authors: Duduk S. L. , Koroleva E. G.
Published: February 2023

The article is presented the supervision of the authors of case mixed (atypical) dementia with Alzheimer's disease. The evaluation of patient is carried out with using modern functional, neurointrascopic and psychometric methods of diagnostics. This research detected as Alzheimer’s nature of disease, so and vascular disturbance, that lead to clinical picture of mixed dementia with Alzheimer's disease.
THE ACETYLATED STATUS: PRESENT-DAY POINT OF VIEW ON THE SUBJECT (references review)
Authors: Satyrova T. V.
Published: February 2023

The study of acetylated polymorphism does not lose its actuality not only because plenty of remedies and carcinogenic substances metabolize by means of acetylization reactions, but also because much success has been achieved in the understanding of molecular bases of acetylation. Just these genetically due variations of remedy metabolism are one of the causes of individual peculiarities of pharmacotherapeutic effects. A man has two discovered genes, responsible for the activities of N-acetyltransferase enzyme - NAT1 и NAT2. The research has shown, that some alleles of these genes influence individual sensitivity to single illnesses.
CONTRIBUTORY FACTORS OF FREQUENT RELAPSES OF RESPIRATORY PAPILLOMATOSIS OF LARYNX IN CHILDREN
Authors: Merkulova E. P. , Baranaeva E. A. , Stulba E. I. , Mazanik O. A.
Published: February 2023

By the additional inclusion of fibrogastroduodenoscopy of the investigation to the algorithm of the examination of children with recurrent respiratory papillomatosis of larynx (n = 7), registered on the clinical books of the specialists in otorhinolaryngology in Minsk, 85,7 % of children (n = 6/7) revealed different variants of кислотозависимой pathology of the upper parts of gastrointestinal tract. Of the examined children, 42,9 % (n = 3/7) revealed respiratory impairment of obstructive type (latent, slight stage). 100 % of the children (n = 7/7) were diagnosed to possess disbalance of immunological activity of phagocyte section to the variable extent of evidence.
EXPERIENCE OF THE LOCAL TREATMENT OF WARTS AND POINTED CANDYLOMAS
Authors: Pankratov O. V. , Pankratov V. G. , Yahnichky G. G. , Drobyshevskaya E. A.
Published: February 2023

The clinical effectiveness and safety of the application of medicine Solcoderm has been studied during the treatment of 108 patients with warts (65 with viral warts and 33 with plantar ones) and 63 patients with pointed genital and anogenital candylomas. Of these, 62,0 % of the patients lost warts after a single application of Solcoderm, 21,3 % - after a second application and 11,1 % - after a third one. In total, 102 of the 108 patients became convalescent, i.e. 94,4 %. All the screened patients with pointed candylomas became clinically convalescent: after a single application of Solcoderm - in 68,3 % of cases, after a second application - in 23,8 % and a third one - in 7,9 % of the patients.