bluuebunny/crossref_metadata_2025 huggingface dataset:
Safety of Cochlear Implantation in Children 12 Months or Younger: Systematic Review and Meta‐analysis
Authors: Sbeih Firas , Bouzaher Malek H. , Appachi Swathi , Schwartz Seth , Cohen Michael S. , Carvalho Daniela , Yoon Patricia , Liu Yi‐Chun Carol , Anne Samantha
Published: January 2022

Objective

To systematically review the literature to determine safety of cochlear implantation in pediatric patients 12 months and younger.

Data Source

Ovid MEDLINE, EMBASE, CINAHL, and Cochrane Central Register of Controlled Trials (CENTRAL) databases were searched from inception to March 20, 2021.

Review Methods

Studies that involved patients 12 months and younger with report of intraoperative or postoperative complication outcomes were included. Studies selected were reviewed for complications, explants, readmissions, and prolonged hospitalizations. Two independent reviewers screened all studies that were selected for the systematic review and meta‐analysis. All studies included were assessed for quality and risk of bias.

Results

The literature search yielded 269 studies, of which 53 studies underwent full‐text screening, and 18 studies were selected for the systematic review and meta‐analysis. A total of 449 patients and 625 cochlear implants were assessed. Across all included studies, major complications were noted in 3.1% of patients (95% CI, 0.8‐7.1) and 2.3% of cochlear implantations (95% CI, 0.6‐5.2), whereas minor complications were noted in 2.4% of patients (95% CI, 0.4‐6.0) and 1.8% of cochlear implantations (95% CI, 0.4‐4.3). There were no anesthetic complications reported across all included studies.

Conclusion

The results of this systematic review and meta‐analysis suggest that cochlear implantation in patients 12 months and younger is safe with similar rates of complications to older cohorts.
Transcriptomic analysis of the maize inbred line Chang7-2 and a large-grain mutant tc19
Authors: Zhang Yanrong , Jiao Fuchao , Li Jun , Pei Yuhe , Zhao Meiai , Song Xiyun , Guo Xinmei
Published: January 2022

Backgrounds

Grain size is a key factor in crop yield that gradually develops after pollination. However, few studies have reported gene expression patterns in maize grain development using large-grain mutants. To investigate the developmental mechanisms of grain size, we analyzed a large-grain mutant, named tc19, at the morphological and transcriptome level at five stages corresponding to days after pollination (DAP).

Results

After maturation, the grain length, width, and thickness in tc19 were greater than that in Chang7-2 (control) and increased by 3.57, 8.80, and 3.88%, respectively. Further analysis showed that grain width and 100-kernel weight in tc19 was lower than in Chang7-2 at 14 and 21 DAP, but greater than that in Chang7-2 at 28 DAP, indicating that 21 to 28 DAP was the critical stage for kernel width and weight development. For all five stages, the concentrations of auxin and brassinosteroids were significantly higher in tc19 than in Chang7-2. Gibberellin was higher at 7, 14, and 21 DAP, and cytokinin was higher at 21 and 35 DAP, in tc19 than in Chang7-2. Through transcriptome analysis at 14, 21, and 28 DAP, we identified 2987, 2647 and 3209 differentially expressed genes (DEGs) between tc19 and Chang7-2. By using KEGG analysis, 556, 500 and 633 DEGs at 14, 21 and 28 DAP were pathway annotated, respectively, 77 of them are related to plant hormone signal transduction pathway. ARF3, AO2, DWF4 and XTH are higher expressed in tc19 than that in Chang7-2.

Conclusions

We found some DEGs in maize grain development by using Chang7-2 and a large-grain mutant tc19. These DEGs have potential application value in improving maize performance.
Environmental spreading of clinically relevant carbapenem-resistant gram-negative bacilli: the occurrence of blaKPC-or-NDM strains relates to local hospital activities
Authors: Pereira Alex Leite , de Oliveira Pâmela Maria , Faria-Junior Célio , Alves Everton Giovanni , de Castro e Caldo Lima Glaura Regina , da Costa Lamounier Thaís Alves , Haddad Rodrigo , de Araújo Wildo Navegantes
Published: January 2022

Background

Aquatic matrices impacted by sewage may shelter carbapenem-resistant (CR) Gram-negative bacilli (GNB) harboring resistance genes of public health concern. In this study, sewage treatment plants (STPs) servicing well-defined catchment areas were surveyed for the presence of CR-GNB bearing carbapenemase genes (blaKPC or blaNDM).

Results

A total of 325 CR-GNB were recovered from raw (RS) and treated (TS) sewage samples as well as from water body spots upstream (UW) and downstream (DW) from STPs. Klebsiella-Enterobacter (KE) group amounted to 116 isolates (35.7%). CR-KE isolates were recovered from TS, DW (35.7%) and RS samples (44.2%) (p = 0.001); but not from UW samples. KE isolates represented 65.8% of all blaKPC or blaNDM positive strains. The frequency of blaKPC-or-NDM strains was positively associated with the occurrence of district hospitals located near STPs, as well as with the number of hospitalizations and of sewer connections serviced by the STPs. blaKPC-or-NDM strains were recovered from ST samples in 7 out of 14 STPs, including four tertiary-level STPs; and from 6 out of 13 DW spots whose RS samples also had blaKPC-or-NDM strains.

Conclusions

Clinically relevant GNB bearing blaKPC-or-NDM resist sewage treatments and spread into environmental aquatic matrices mainly from STPs impacted by hospital activities.
Telerehabilitation of acute musculoskeletal multi-disorders: prospective, single-arm, interventional study
Authors: Costa Fabíola , Janela Dora , Molinos Maria , Lains Jorge , Francisco Gerard E. , Bento Virgílio , Dias Correia Fernando
Published: January 2022

Background

Acute musculoskeletal (MSK) pain is very common and associated with impaired productivity and high economic burden. Access to timely and personalized, evidence-based care is key to improve outcomes while reducing healthcare expenditure. Digital interventions can facilitate access and ensure care scalability.

Objective

Present the feasibility and results of a fully remote digital care program (DCP) for acute MSK conditions affecting several body areas.

Methods

Interventional single-arm study of individuals applying for digital care programs for acute MSK pain. Primary outcome was the mean change between baseline and end-of-program in self-reported Numerical Pain Rating Scale (NPRS) score and secondary outcomes were change in analgesic consumption, intention to undergo surgery, anxiety (GAD-7), depression (PHQ-9), fear-avoidance beliefs (FABQ-PA), work productivity (WPAI-GH) and engagement.

Results

Three hundred forty-three patients started the program, of which 300 (87.5%) completed the program. Latent growth curve analysis (LGCA) revealed that changes in NPRS between baseline and end-of-program were both statistically (p < 0.001) and clinically significant: 64.3% reduction (mean − 2.9 points). Marked improvements were also noted in all secondary outcomes: 82% reduction in medication intake, 63% reduction in surgery intent, 40% in fear-avoidance beliefs, 54% in anxiety, 58% in depression and 79% recovery in overall productivity. All outcomes had steeper improvements in the first 4 weeks, which paralleled higher engagement in this period (3.6 vs 3.2 overall weekly sessions, p < 0.001). Mean patient satisfaction score was 8.7/10 (SD 1.26).

Strengths and limitations

This is the first longitudinal study demonstrating the feasibility of a DCP for patients with acute MSK conditions involving several body areas. Major strengths of this study are the large sample size, the wide range of MSK conditions studied, the breadth of outcomes measured, and the very high retention rate and adherence level. The major limitation regards to the absence of a control group.

Conclusions

We observed very high completion and engagement rates, as well as clinically relevant changes in all health-related outcomes and productivity recovery. We believe this DCP holds great potential in the delivery of effective and scalable MSK care.

Trial registration

NCT, NCT04092946. Registered 17/09/2019;
Development of a blended emergent research training program for clinical nurses (part 1)
Authors: Chen Qirong , Li Zeen , Tang Siyuan , Zhou Chuyi , Castro Aimee R. , Jiang Shan , Huang Chongmei , Xiao Jinnan
Published: January 2022

Background

Nursing research training is important for improving the nursing research competencies of clinical nurses. Rigorous development of such training programs is crucial for ensuring the effectiveness of these research training programs. Therefore, the objectives of this study are: (1) to rigorously develop a blended emergent research training program for clinical nurses based on a needs assessment and related theoretical framework; and (2) to describe and discuss the uses and advantages of the ADDIE model (Analysis, Design, Development, Implementation, Evaluation) in the instructional design and potential benefits of the blended emergent teaching method.

Methods

This intervention development study was conducted in 2017, using a mixed-methods design. A theoretical framework of blended emergent teaching was constructed to provide theoretical guidance for the training program development. Nominal group technique was used to identify learners’ common needs and priorities. The ADDIE model (Analysis, Design, Development, Implementation, Evaluation) was followed to develop the research training program for clinical nurses based on the limitations of current nursing research training programs, the needs of clinical nurses, and the theoretical foundation of blended emergent teaching.

Results

Following the ADDIE model, a blended emergent research training program for clinical nurses to improve nursing research competence was developed based on the needs of clinical nurses and the theoretical framework of blended emergent teaching.

Conclusions

This study indicates that nominal group technique is an effective way to identify learners’ common needs and priorities, and that the ADDIE model is a valuable process model to guide the development of a blended emergent training program. Blended emergent teaching is a promising methodology for improving trainees’ learning initiative and educational outcomes. More empirical studies are needed to further evaluate blended emergent teaching to promote the development of related theories and practice in nursing education.
Determining levels of nurse burnout during the COVID-19 pandemic and Lebanon’s political and financial collapse
Authors: Clinton Michael , Bou-Karroum Karen , Doumit Myrna Abdullah , Richa Nathalie , Alameddine Mohamad
Published: January 2022

Background

The COVID-19 pandemic compounded political and financial pressures on the nursing workforce in Lebanon. The government resigned in October 2019 in response to the popular uprising that called for an end to corruption and economic mismanagement 5 months before the first COVID-19 case appeared in the country. The continuing crises and the added stress of COVID-19 has increased the risk of occupational burnout and turnover in the nursing workforce. Therefore, valid and reliable measurement is imperative to determine burnout levels, prioritize intervention, and inform evidence-based workforce policy and practice. The primary aim of the study was to delineate burnout levels and cut-points in a national sample of nurses to inform workforce policies and prioritize interventions.

Methods

Multidimensional and unidimensional Rasch analyses of burnout data collected from a national convenience sample of 457 hospital nurses 9–12 months after Lebanon’s political and economic collapse began. The data were collected in July–October 2020.

Results

Multidimensional Rasch analysis confirmed that the Copenhagen Burnout Inventory has three highly correlated unidimensional scales that measure personal burnout, work-related burnout, and client-related burnout. Except for a ceiling effect of ~ 2%, the three scales have excellent measurement properties. For each scale, Rasch rating scale analysis confirmed five statistically different nurse burnout levels. The mean personal burnout scores and work-related burnout scores (50.24, 51.11 respectively) were not higher than those reported in the international literature. However, the mean client-related burnout score of 50.3 was higher than reported for other countries. Compared with a baseline study conducted at the beginning of Lebanon’s political and economic crises, only client-related burnout scores were higher p. <.01.

Conclusions

The CBI scales are reliable and valid measures for monitoring nurse burnout in crises torn countries. Stakeholders can use the CBI scales to monitor nurse burnout and prioritize burnout interventions. Urgent action is needed to reduce levels of client-related burnout in Lebanon’s nursing workforce.
IgE is associated with exacerbations and lung function decline in COPD
Authors: Lommatzsch Marek , Speer Timotheus , Herr Christian , Jörres Rudolf A. , Watz Henrik , Müller Achim , Welte Tobias , Vogelmeier Claus F. , Bals Robert ,   for the COSYCONET study group
Published: January 2022

Background

Both allergen-specific IgE and total IgE in serum play a major role in asthma. However, the role of IgE in chronic obstructive pulmonary disease (COPD) is poorly understood. It was the aim of this study to systematically analyze the relationship between serum IgE levels and disease characteristics in large COPD cohorts.

Methods

COSYCONET is a comprehensively characterized cohort of patients with COPD: total IgE and IgE specific to common aeroallergens were measured in serum of 2280 patients, and related to clinical characteristics of the patients. WISDOM is another large COPD population (2477 patients): this database contains the information whether total IgE in serum was elevated (≥ 100 IU/l) or normal in patients with COPD.

Results

Both in COSYCONET and WISDOM, total IgE was elevated (≥ 100 IU/l) in > 30% of the patients, higher in men than in women, and higher in currently than in not currently smoking men. In COSYCONET, total IgE was elevated in patients with a history of asthma and/or allergies. Men with at least one exacerbation in the last 12 months (50.6% of all men in COSYCONET) had higher median total IgE (71.3 IU/l) than men without exacerbations (48.3 IU/l): this difference was also observed in the subgroups of not currently smoking men and of men without a history of asthma. Surprisingly, a history of exacerbations did not impact on total IgE in women with COPD. Patients in the highest tertiles of total IgE (> 91.5 IU/ml, adjusted OR: 1.62, 95% CI 1.12–2.34) or allergen-specific IgE (> 0.19 IU/ml, adjusted OR: 2.15, 95% CI 1.32–3.51) were at risk of lung function decline (adjusted by: age, gender, body mass index, initial lung function, smoking status, history of asthma, history of allergy).

Conclusion

These data suggest that IgE may play a role in specific COPD subgroups. Clinical trials using antibodies targeting the IgE pathway (such as omalizumab), especially in men with recurrent exacerbations and elevated serum IgE, could elucidate potential therapeutic implications of our observations.
Explanatory models of post-traumatic stress disorder (PTSD) and depression among Afghan refugees in Norway
Authors: Brea Larios Dixie , Sandal Gro Mjeldheim , Guribye Eugene , Markova Valeria , Sam David Lackland
Published: January 2022

Background

The current situation in Afghanistan makes it likely that we are facing a new wave of Afghan refugees, warranting more knowledge about how to deal with mental health problems among them. This study aims to gain more knowledge on Explanatory Models (EM) of depression and post-traumatic stress disorders (PTSD) among Afghan refugees resettled in Norway.

Methods

We conducted six gender-separated, semi-structured focusgroup interviews based on vignettes with Afghan refugees (total N = 27). The vignettes described a fictional character with symptoms of either depression or PTSD symptoms in line with DSM-5 and ICD-10 criteria.

Results

The findings showed that EM varied with gender, age, generation, and migration stories. Participants suggested different potential causes, risk factors, and ways of managing symptoms of depression and PTSD depending on the context (e.g., in Norway vs. Afghanistan). In describing the causes of the depression/PTSD in the vignettes, females tended to emphasize domestic problems and gender issues while males focused more on acculturation challenges. The younger males discussed mostly traumatic experiences before and during flight as possible causes.

Conclusion

The practice of condensing a single set of EMs within a group may not only be analytically challenging in a time-pressed clinical setting but also misleading. Rather, we advocate asking empathic questions and roughly mapping individual refugee patients’ perceptions on causes and treatment as a better starting point for building trusting relationships and inviting patients to share and put into practice their expertise about their own lives.
Acute, subacute oral toxicity and Ames test of Py-mulin: an antibacterial drug candidate
Authors: Fan Yuan , Fu Yunxing , Zhou Yuhang , Liu Yu , Hao Baocheng , Shang Ruofeng
Published: January 2022

Background

Py-mulin is a new pleuromutilin derivative with potent antibacterial activities in vitro and in vivo, suggesting this compound may lead to a promising antibacterial drug after further development. The present study is aimed to evaluate the acute and subacute oral toxicity, and the genotoxicity with the standard Ames test according to standard protocols.

Methods

Acute oral toxicity of Py-mulin was determined using Kunming mice. The 28-day repeated dose oral toxicity study in SD rats was performed according to OECD guideline No. 407. The bacterial reverse mutation (Ames test) was carried out using four Salmonella typhimurium (S. typhimurium) strains TA97, TA98, TA100 and TA1535 with and without S9 metabolic activation.

Results

The LD50 values in acute oral toxicity were 2973 mg/kg (female mice) and 3891 mg/kg (male mice) calculated by the Bliss method. In subacute toxicity study, 50 mg/kg Py-mulin did not induce any abnormality in body weight, food consumption, clinical sign, hematology, clinical chemistry, organ weight, and histopathology in all of the treatment groups. However, high doses of Py-mulin (100 and 300 mg/kg) displayed slightly hepatotoxicity to female rats. Furthermore, Py-mulin did not significantly increase the number of revertant colonies of four standard S. typhimurium strains with the doses of 0.16–1000 μg/plate in the Ames study.

Conclusions

Based on our findings, our study provides some information for the safety profile of Py-mulin.
3D technologies for intangible cultural heritage preservation—literature review for selected databases
Authors: Skublewska-Paszkowska Maria , Milosz Marek , Powroznik Pawel , Lukasik Edyta
Published: January 2022

Conservation of cultural heritage is nowadays a very important aspect of our lives. Thanks to such legacy we gain knowledge about our ancestors, methods of production and ways of their life. The rapid development of 3D technology allows for more and more faithful reflection of this area of life. The rich cultural heritage, both tangible and intangible, can be preserved for future generations due to the use of advanced 3d technologies. They provide the means of documenting, recovering and presenting items of cultural heritage. Not only buildings or monuments are taken into account. An important aspect of our culture is intangible cultural heritage (ICH), including acting, crafting or storytelling, passed down from generation to generation. Due to the rapid development of civilisation and the migration of people, this type of culture is often forgotten. That is why the preservation of ICH is an important element of today world. The main aim of this study, on the basis of the gathered papers, is to identify: (1) the general state of use of 3D digital technologies in ICH; (2) the topics and themes discussed; (3) the technologies used in the study; (4) locations of research centres conducting such studies; and (5) the types of research carried out. The methodology consists of the following main steps: defining study questions, searching query development, selection of publications in Scopus, Web of Knowledge and IEEE Xplore, finally the study execution and the analysis of the obtained results. The results show that for ICH the most often used technologies are: 3D visualisation, 3D modelling, Augmented Reality, Virtual Reality and motion capture systems.
Evolution of the geological structure and mechanical properties due to the collision of multiple basement topographic highs in a forearc accretionary wedge: insights from numerical simulations
Authors: Miyakawa Ayumu , Noda Atsushi , Koge Hiroaki
Published: January 2022

We propose a conceptual geological model for the collision of multiple basement topographic highs (BTHs; e.g., seamounts, ridges, and horsts) with a forearc accretionary wedge. Even though there are many BTHs on an oceanic plate, there are few examples of modeling the collision of multiple BTHs. We conducted numerical simulations using the discrete element method to examine the effects of three BTH collisions with forearcs. The typical geological structure associated with a BTH collision was reproduced during the collision of the first BTH, and multiple BTH collisions create a cycle of formation of BTH collisional structures. Each BTH forces the basal décollement to move up to the roof décollement, and the roof décollement becomes inactive after the passage of the BTH, and then the décollement moves down to the base. As the active décollement position changes, the sequences of underthrust sediments and uplifted imbricate thrusts are sandwiched between the décollements and incorporated into the wedge. At a low horizontal compressive stress, a “shadow zone” is formed behind (i.e., seaward of) the BTH. When the next BTH collides, the horizontal compressive stress increases and tectonic compaction progresses, which reduce the porosity in the underthrust sediments. Heterogeneous evolution of the geological and porosity structure can generate a distinctive pore pressure pattern. The underthrust sediments retain fluid in the “shadow” of the BTH. Under the strong horizontal compressive stresses associated with the next BTH collision, pore pressure increases along with a rapid reduction of porosity in the underthrust sediments. The distinctive structural features observed in our model are comparable to the large faults in the Kumano transect of the Nankai Trough, Japan, where a splay fault branches from the plate boundary and there are old and active décollements. A low-velocity and high-pore-pressure zone is located at the bottom of the accretionary wedge and in front (i.e., landward) of the subducting ridge in the Kumano transect. This suggests that strong horizontal compressive stresses associated with the current BTH collision has increased the pore pressure within the underthrust sediments associated with previous BTHs.
Performance of cement-stabilized weak subgrade for highway embankment construction in Southeast Nigeria
Authors: Ifediniru Chukwuka , Ekeocha Nnamdi E.
Published: January 2022

Soils with poor shear strength and high compressibility underlie the wetlands of southern Nigeria. They are susceptible to intolerable settlements and account for greater than 60% of the soils in the region. While requiring embankments for any infrastructure construction, these weak soils pose significant threat to the construction and service life of highway pavements in southeastern Nigeria. Therefore, this research investigates shear strength improvement of a highway embankment’s weak subgrade soil after mass stabilization of soil with 6 and 10% Portland cement. The factor of safety against shear failure of the embankment was analyzed for un-stabilized subgrade and then cement-stabilized subgrade. The analysis was carried out for embankment heights of 4, 5, 6 and 7 m using the limit equilibrium method. Thick soft clayey silt with Cu range of 9 to 15 kPa underlay the embankment, upon improvement, the Cu of 154 and 208 kPa was obtained for 6 and 10% stabilization respectively. The FoS for the embankment on Un-stabilized soil ranged from 0.88 for a 7 m embankment to 1.2 for a 4 m embankment. The FoS after mass stabilization of 1 to 5 m soil ranged between 1.77 and 5.22 for the different embankment heights. Stability was better improved as depth of mass stabilization and cement content increased. A linear relationship was observed to exist between the cement content, strength of the improved soils, stabilization depth and the factor of safety.
A case report of duodenal arteriovenous malformation: usefulness of intraoperative indocyanine green angiography for precise identification of the lesion
Authors: Kurata Yoshihiro , Hayano Koichi , Matsusaka Keisuke , Mamiya Hisashi , Uesato Masaya , Murakami Kentaro , Kano Masayuki , Toyozumi Takeshi , Matsumoto Yasunori , Suito Hiroshi , Isozaki Tetsuro , Ohira Gaku , Hayashi Hideki , Matsubara Hisahiro
Published: January 2022

Background

Arteriovenous malformation (AVM) of the gastrointestinal (GI) tract can cause bleeding. The treatment choice for GI tract AVM is surgical resection of the involved bowel segment with complete resection of the nidus. The AVM formed in the duodenum or pancreatic head could also cause gastrointestinal bleeding, and there are several reports of pancreaticoduodenectomy as its treatment. However, if the area of AVM can be accurately identified during surgery, it may be possible to completely resect the AVM while preserving the organ. We report a case of duodenal AVM in a patient successfully treated with a subtotal stomach-preserving duodenal bulb resection using intraoperative indocyanine green (ICG) angiography technique.

Case presentation

An 18-year-old man was diagnosed with duodenal AVM after several examinations for anemia and was referred to our hospital for further treatment. Preoperative imaging studies showed that the inflow vessels of this duodenal AVM were the inferior pyloric artery and the superior duodenal artery, and the AVM was localized to the duodenal bulb. Thereafter, stomach-preserving duodenal bulb resection preceded by ligation of the inflow vessels was performed. During the surgery, ICG angiography clearly demonstrated the area, where the nidus was distributed, and a duodenal bulb resection with complete resection of the AVM was successfully performed. There was no recurrence at the 6-month follow-up.

Conclusions

Intraoperative ICG angiography was a useful procedure for precise identification of the AVM of the GI tract.
How time-inconsistent preferences influence venture capital exit decisions? A new perspective for grandstanding
Authors: Li Yanzhao , Guo Ju-e , Sun Shaolong , Li Yongwu
Published: January 2022

Considering that the assumption of time consistency does not adequately reveal the mechanisms of exit decisions of venture capital (VC), this study proposes two kinds of time-inconsistent preferences (i.e., time-flow inconsistency and time-point inconsistency) to advance research in this field. Time-flow inconsistency is in line with the previous time inconsistency literature, while time-point inconsistency is rooted in the VC fund’s finite lifespan. Based on the assumption about the strategies guiding future behaviors, we consider four types of venture capitalists: time-consistent, time-point-inconsistent, naïve, and sophisticated venture capitalists, of which the latter three are time-inconsistent. We derive and compare the exit thresholds of these four types of venture capitalists. The main results include: (1) time-inconsistent preferences accelerate the exits of venture capitalists; (2) the closer the VC funds expiry dates are, the more likely time-inconsistent venture capitalists are to accelerate their exits; and (3) future selves caused by time-flow inconsistency weaken the effect of time-point inconsistency. Our study provides a behavioral explanation for the empirical fact of young VCs’ grandstanding.
Money and inflation in Switzerland
Authors: Kugler Peter , Reynard Samuel
Published: January 2022

This paper characterizes the relationship between monetary aggregates, inflation and economic activity in Switzerland since the mid-1970s. Traditional forms of money demand and quantity theory relationships have remained stable over the whole period. Broad money excesses over trend values, accounting for a secular decline in interest rates and thus in trend velocity, have been followed by persistently higher inflation and output with the usual monetary policy transmission lags. Money and exchange rate fluctuations can explain the major inflation developments in Switzerland over the past four decades.
The Ideology of Liberalism and Socialism in the Context of Cardinal Stefan Wyszyński’s Personalist Concept of Social Life
Authors: Ficek Ryszard
Published: January 2022

Ideologia liberalizmu i socjalizmu w kontekście personalistycznej koncepcji życia społecznego Stefana Wyszyńskiego
Prezentowany artykuł ukazuje personalistyczną koncepcję życia społecznego w ujęciu Stefana Wyszyńskiego w kontekście ideologii liberalnego kapitalizmu i ideologicznych koncepcji nawiązujących do idei socjalistycznych. Wiodącą tezą niniejszych analiz jest ukazanie powyższych systemów nie tyle w kategoriach antynomicznych, czy analogicznych. Ideologia liberalna i związany z nią kapitalizm powstały w połowie XIX wieku i od tego czasu nieustannie ewoluowały, często zmieniając swoje główne parametry i specyfikę. Z drugiej strony, ideologia socjalistyczna ukształtowała się jako koncepcja przeciwna kapitalistycznej rzeczywistości XIX wieku. Jednak nigdy tak naprawdę nie istniała ona w jednolitej formie. Analizowana ideologia, określana jako doktryna socjalistyczna, była w istocie hybrydą idei liberalno-kapitalistycznych i – poniekąd – neofeudalnej biurokracji. Bardziej szczegółowa analiza powyższych koncepcji i ich krytyczna reinterpretacja w kontekście myśli personalistycznej Wyszyńskiego pozwala uświadomić niebezpieczeństwa związane z motywowanym ideologicznie propagowaniem skrajnych, często zafałszowanych koncepcji osoby ludzkiej i ich zastosowaniem w konkretnych realiach współczesnego świata.
O 20 do XXI: práticas de ensino desafiadoras em um tempo de tormentas
Authors: Nunes Rodrigo Dos Reis , Lima Josiane Bispo Cruz
Published: January 2022

Este trabalho buscou discutir acerca das práticas de ensino desafiadoras frente às instabilidades do século XXI e, de forma mais específica, no ano 2020, por conta da pandemia do novo coronavírus. Esta pesquisa qualitativa de caráter exploratório utilizou como instrumento de levantamento de dados, além da bibliografia consultada, um questionário semiestruturado que versou sobre questões direcionadas a docentes da rede pública e privada de ensino sobre a realidade de trabalho frente à pandemia e como eles têm lidado com as tecnologias digitais da informação e da comunicação (TDIC). Como resultado, pudemos constatar a presença de tensões relatadas pelos docentes que foram abruptamente postos à prática do ensino remoto, a necessidade de domínio de tecnologias específicas, além de constatarmos a importância da oferta de formação adequada para preparar melhor esses profissionais.
NEGÓCIO JURÍDICO PROCESSUAL EM SEDE DE EXECUÇÃO FISCAL COMO FORMA DE ACESSO À JUSTIÇA
Authors: Rennó Gabriela Machado , Carvalho Silzia Alves
Published: January 2022

A relação antagônica entre fisco e contribuinte estabelece barreiras que, além de gerar colapso no Poder Judiciário com congestionamento processual, não resulta em efetiva arrecadação e, por consequência, não representa efetivo acesso à justiça. Ante a morosidade sistêmica das execuções fiscais, bem como a imprescindibilidade de posturas do direito público consensual, compreende-se a consensualidade como forma de promover a pacificação. Nessa linha, o presente artigo objetiva instigar reflexões sobre o Negócio Jurídico Processual em sede de execução fiscal como forma de efetivo acesso à justiça, na medida em que tal procedimento é um mecanismo consensual que visa à arrecadação fiscal.
TERMOFOSFATO E COBERTURA MORTA NA PRODUTIVIDADE E QUALIDADE DE FRUTÍFERAS CULTIVADAS NA ALTA PAULISTA
Authors: Nasser Maurício Dominguez , Montes Rafael Marangoni , Kohori Carolina Bugalho , Montagnoli Maria Carolina Diniz , Furlaneto Fernanda De Paiva Badiz
Published: January 2022

A Alta Paulista se destaca na produção de frutas, porém os solos da região, de modo geral, apresentam textura arenosa, sendo mais sujeitos a lixiviação de nutrientes, o que pode resultar em baixa fertilidade caso não se adotar práticas de cultivo mais racionais. Objetivou-se avaliar o termofosfato associado com cobertura morta na produtividade e qualidade de frutíferas cultivadas na Alta Paulista. Os experimentos foram conduzidos em pomares comerciais de acerola, goiaba e lima ácida ‘Tahiti’. Os tratamentos foram 1- Testemunha (T), 2- Testemunha mais cobertura morta (CM), sendo a palhada direcionada sob a copa da frutífera, 3- Testemunha com cobertura morta e aplicação do termofosfato Yoorin®, e 4- Testemunha com aplicação de Yoorin®. Foi utilizado delineamento experimental em blocos, com 4 tratamentos e 5 repetições. Os dados foram submetidos à análise de variância para o Teste F, e as médias comparadas pelo Teste Tukey ao nível de 5% de significância. O uso do termofosfato é viável e traz benefícios na produtividade e qualidade da acerola, goiaba e lima ácida ‘Tahiti’. Sua ação é mais significativa quando aplicado diretamente no solo.
Effects of Differential Presentation of Noun Types on Sentence Processing in Elderly Adults: An Eye-tracking Study
Authors: Kim Suji , Sung Jee Eun
Published: January 2022

Objectives: The purpose of this study is to investigate how aging influences sentence processing when noun-phrases are presented differently.Methods: A total of 40 participants participated in the study ranging in age from 19 to 71. All were presented with sentences and pictures under either dative or accusative conditions. After that, they were asked to judge if the sentences were correct or incorrect.Results: First, there were significant differences between the older adults and younger adults in accuracy. The older group showed lower accuracy in the sentence judgment task. Second, there were significant differences between the older adults and younger adults in response time. The older group needed more time due to their lower cognitive resources. They made more errors when accusative noun phrases were provided. Third, the fixation proportion of the target stimulus between regions were significant in both types of dative and accusative noun phrase presentation. The older group showed lower proportions in the last region of the sentence.Conclusion: These results shows that both the elderly and the young gradually deal with the meaning of words through the noun phrase information. However, the elderly showed difficulty in assigning the correct thematic roles by using case-markers, given the lower proportion of fixation in the region where the target stimuli are presented. It is expected that difficulties in the communication process of the elderly will be better understood through this study.
A Survey on AAC Fringe Vocabulary to Support Personal Assistance Service
Authors: Park Daeun , Shin Sangeun
Published: January 2022

Objectives: There are increasing demands for personal assistance services which help the disabled to carry out their daily life. To use augmentative and alternative communication (AAC) approaches more effectively in daily communication, it is essential to include the appropriate core and fringe vocabulary in the AAC system. Considering the fact that there are few studies in Korea which have reported fringe vocabulary compared to core vocabulary, this study is aimed to develop a noun list that can be used to promote interactive communication between the disabled and their assistants in each communication situation.Methods: A literature review was conducted to elicit frequently used nouns in each communication situation. Then, a survey was carried out to identify nouns with high word commonality across 105 personal assistants.Results: Sixty-three nouns with more than 50% of word commonality across personal assistants were identified from the 244 fringe vocabulary; consisting of 112 nouns in the area of going out, 29 in cleaning, 27 in personal hygiene, 26 in cooking, 20 in meal supporting, 20 in other service areas, and 10 in commuting.Conclusion: The identified nouns are expected to help people with complex communication needs to express their needs and wants more clearly and effectively using those nouns embedded in their AAC systems. The list of nouns can be used not only for people who receive personal assistance services, but also for people who rely on AAC systems to express their daily needs.
Meslek yüksek okulu öğrencilerinin ruhsal durum algıları ile müzik tercihlerinin incelenmesi
Authors: Soysal Gonca , Soysal N. Fikri , Balcı Elçin
Published: January 2022

Bu araştırma, Meslek Yüksekokulu öğrencilerinin ruhsal durum algılarının
değerlendirilip, öğrencilerin mevcut ruhsal durumlarını ortaya koymak
suretiyle ruhsal semptom taraması yapılması ve müzik tercihlerinin ruhsal
durumlarına nasıl etki ettiğini belirlemek için yapılmıştır. Tanımlayıcı kesitsel
nitelikli araştırmanın evrenini, Tokat Gaziosmanpaşa Üniversitesi Pazar Meslek
Yüksekokulunda 2016-2017 güz yarıyılında okuyan öğrenciler oluşturmaktadır.
Örneklem hesabına gidilmemiş olup araştırmaya katılmayı kabul eden 198
öğrencinin katılımıyla (ulaşma oranı %80.2) çalışma gerçekleştirilmiştir.
Araştırmaya katılan öğrencilerin %73.7’si kadın, %26.3’ü erkek olup yaş
ortalaması 19.7±2.2 yıldır. Ruhsal problem varlığı bulunan öğrenci oranı
%57.1’dir. Katılımcıların GSI puan ortalamasına göre ruhsal problem varlığı
bulunan alt gruplar arasında ilk üç sırada obsesif kompulsif, paranoid düşünceler
ve kişiler arası duyarlılık bozuklukları bulunmuştur. Cinsiyet, yaşanılan yer ve
ekonomik durum ile bazı SCL 90 alt grup puanları arasında istatistiki anlamlılık
düzeyinde farklılaşma vardır. Öğrencilerin dinledikleri müzikler arasında ilk
üç sırada pop müzik, arabesk ve halk müziği olduğu tespit edilmiştir. Buna
istinaden ülkemiz üniversitelerinin de düzenli olarak ruhsal semptom tarama
çalışmalarının yapılarak, müziğinde olumlu etkilerinden yararlanmak suretiyle
disiplinler arası çalışmalar ve eylem planları oluşturması önerilmektedir.
Regulatory Requirements of Quality Assurance Program in Nuclear Medicine – Review of the Procedures
Authors: Hallab Reda , Eddaoui khalida , Ouabi Hmad , Raïs Aouad Nouzha Ben
Published: January 2022

The quality assurance program ensures that the entire radiological system and associated equipment are functioning properly and optimally. To this end, it is essential that a quality assurance program be in place in each medical facility where ionizing radiation sources are used, to verify the proper functioning of these instruments as well as the radionuclides measured in nuclear medicine. In addition, the procedures of the quality assurance program must comply with regulatory requirements and international recommendations. The method of this study is to review the regulatory requirements adopted by different countries regarding the quality assurance program procedures as well as various recent scientific works and those published by the International Atomic Energy Agency. In addition, to compare the radiation protection requirements of the procedures of the mentioned works; exposure justification and optimization, quality control, registration system, professional training and audit system and to suggest improvements. The result of the review study, add a procedure to the quality assurance program, so that the quality assurance attempts to cover all procedures involving sources of ionizing radiation, thus ensuring compliance with the standards of radiological safety in nuclear medicine facilities.
Study of Effect of Vitamin D Supplementation on Selected Hepatic and Renal Parameters in T2DM with Vitamin D Deficiency
Authors: S Jankar Deepali , C Wingkar Kanchan , Sontakke Ajit V , D Bodhe Chintamani
Published: January 2022

Introduction:- Vitamin D has been studied as modifiable risk factor in DM. Apart from its role in glucose homeostasis, the anti-inflammatory effect of vitamin D is claimed to have important effect on beta cell survival and on hepatic cells. Vitamin D is said to have anti-inflammatory, anti-proliferative and anti-fibrotic actions in liver. VDD is more prevalent in T2DM, obese and NAFLD even when these conditions occur separately. Literature states the protective effective of vitamin D on kidney. Association of VDD with albuminuria and chronic kidney disease in diabetics has also been reported. Material and Methods:- This is a type of comparative and interventional study. 63 T2DM patients aged 30 – 60 years with VDD were included. Baseline investigations determined blood levels of vitamin D, calcium, phosphate, liver enzymes (AST, ALT, ALP) and serum creatitine. Patients received vitamin D intervention orally in the dose of 2000 IU daily for 12 weeks. After 12 weeks blood levels of vitamin D, calcium, phosphate, liver enzymes (AST, ALT, ALP) and serum creatitine were determined. Results:- There was no correlation of vitamin D with urea, creatinine, calcium, phosphate, AST, ALT and ALP. There was extremely significant rise in vitamin D, significant fall in phosphate level, non-significant fall in creatinine, AST, ALT, ALP and non-significant rise in calcium, urea after 12 weeks of vitamin D supplementation. Conclusion:- There was no correlation of vitamin D with hepatic and renal parameters. Also 12 weeks of vitamin D supplementation had no significant improvement in these parameters in T2DM.
Doped Ceria Catalyst System: Catalyzing Carbon Monoxide Transformation (A-Review)
Authors: Chaudhary Mayankkumar Lakshmanbhai , Kumar Rawesh
Published: January 2022

As ceria chemistry broadens, it is needed to generalize the behavior of ceria surfaces towards molecules for carrying out a reaction. The endowing capacity of mobile oxygen due to rapid redox switching between Ce+4/Ce+3 is a key point for ceria containing surfaces. Herein we have presented a review which is broadly divided into two parts. First part focuses on surface property as how electronic structure, vacancy and surface energy would be modified after interaction of ceria with dopant (noble metal, metal of variable oxidation state, higher valent metal and lower valent metal). The second part focuses on catalysis as how the doped ceria surface influences the carbon monoxide transformations (CO oxidation, CO and H2O reaction, CO and NO reaction, CO and H2 reaction). This through study will be helpful to predict the ceria surface for a designed reaction.
Pyran Heterocyclic Compound as the Prosperous Scaffolds for Biological Sensor (A-Review)
Authors: Suthar Madhuri , Kumbhani Jasmin , D. Bhatt Keyur
Published: January 2022

2H-pyrans and 4H-pyrans, which are six-membered heterocyclic compounds containing oxygen, are a class of biologically dynamic natural and synthetic products that played a key character in bioorganic chemistry and continue to pique attention. Pyrans and their analogues have a prominent position in bioorganic chemistry because of their numerous applications. This analysis explored the most recent advances, as well as the discovery of new methodologies and the diverse biological activities of pyran analogues.
Future Clinical Application of β-galactosidase Stabilized by Magnesium oxide Nanoparticles
Authors: Alshanberi Asim Muhammed , Ansari Shakeel Ahmed
Published: January 2022

The present study demonstrates the application of freshly prepared neem leaf extract as a reducing agent for synthesizing magnesium oxide nanoparticles (MgO-NPs). In silico interaction of Aspergillus oryzae β-galactosidase with MgO-NPs was observed by using molecular docking program Dock v.6.5 while the visual analyses and illustration of protein–ligand complex were investigated by utilizing chimera v.1.6.2 and PyMOL v.1.3 softwares. The prepared nanomatrix provided 83% immobilization yield, and broadened the biocatalytic activity of immobilized β-galactosidase at higher pH and temperature ranges. Immobilized β-galactosidase exhibited greater activity even at 5.0% galactose concentration as compared to the soluble enzyme under similar experimental conditions. Hence, the use of green nanotechnology makes the process inexpensive, and therefore, immobilization of these enzymes on such nanoparticles can help to recover the enzyme, which ultimately decreases the cost of process.
Distribution of Selected Dissolved and Particulate Heavy Metals in Lake Kenyir, Malaysia
Authors: Uning Royston , Adlina Md Nasir Fatin , Suratman Suhaimi
Published: January 2022

This study was conducted to determine the concentration and possible sources of dissolved and particulate heavy metals in Lake Kenyir, Terengganu, Malaysia. The heavy metals studied included Cd, Fe, Pb, Zn and Cu. The findings indicated that the mean concentrations found in the dissolved form for surface waters were in decreasing order of Fe>Zn>Pb~Cu>Cd. A similar trend was also recorded for the particulate form i.e., Fe>Zn>Pb~Cu>Cd. In terms of vertical distribution, most of the heavy metals showed a trend of increasing concentrations from the surface to the bottom waters. The main sources of heavy metals were from anthropogenic activities such as discharge of untreated sewage, surface runoff and boat activity. However, the levels of dissolved heavy metals were still lower compared to other study areas in Malaysia. The dissolved heavy metal concentrations were equivalent with Class II based on the National Water Quality Standard for Malaysia.
Density study of (D (+) mannose + water), (D (+) mannose + water + sodium cyclamate), (D (+) maltose monohydrate + water) and (D (+) maltose monohydrate + water + sodium cyclamate) systems at T = 298.15 K
Authors: J. Kharat Sanjeevan , D. Patil Manisha
Published: January 2022

Effect of different concentrations of aqueous solutions of sodium cyclamate on sugars (mono and disaccharides) are observed by measuring the densities of (sugar + water) and (sugar + water + sodium cyclamate) systems. Densities of aqueous solutions of D (+) mannose (monosaccharide) and D (+) maltose monohydrate (disaccharide) in (0.05, 0.15, 0.3) mol.kg-1 of sodium cyclamate (Na-Cyclamate) at T = 298.15 K have been measured. From experimental values of densities , Vɸ0( partial molar volumes) ΔtrsVɸ0 (partial molar volumes of transfer) ASV (apparent specific volumes) interaction parameters (𝑉𝐴𝐵) and (𝑉𝐴𝐵𝐵 ) have been determined. The calculated values of various parameters have been used to interpret the results in terms of (D (+) mannose – water), (D (+) mannose –water– Na-cyclamate), (D (+) maltose monohydrate – water) and (D (+) maltose monohydrate – water – Na-cyclamate) interactions in sugar– water – Na-cyclamate and quality of taste sense of solutions.
Revealing the Toxicity of Chlorate Through the Analysis of Molecular Interaction using Viscosity Measurements and Apparent Molar Volumes
Authors: V. Rathi Meenakshi
Published: January 2022

While chlorate has the ability to induce flowering in longan, it also has adverse impacts on the crop. Revealing the toxicity of chlorate in the environment is more than just about the environment and about human health, as well.Because of the large introduction of this chemical into the environment from the paper processing industry, there is indeed a lot of concern about its toxicity. Chlorate toxicology in the longan plant has been thoroughly investigated in solutions using viscosities and apparent molar volumes. The hydration of molecules and volume changes are involved in various chemical and biological processes in plant tissues, and their complete understanding demands a good idea for volumetric and viscometric study. It offers good data acquisition techniques for solute, solvent and solvent-solvent interactions. Multi-component systems containing KClO3+ water + ionic solid (ionic solids = KCl, KNO3 ,NH4NO3 and KH2PO4, are currently being worked out to study the dependence of transport properties of potassium chlorate in aqueous electrolyte solutions, with concentrations and temperature of solutions. The assessed kd values are used to predict whether the solvolysis of KClO3 in the presence of other electrolytes is a quick or slow process.