bluuebunny/crossref_metadata_2025 huggingface dataset:
Recently developed industrial dielectric enables RF capacitors for high-kVAR resonant tank use
Authors: Blahins Janis , Apsitis Aigars , Bzhishkian Arman
Published: February 2024

This article describes designer's experience with radiofrequency (RF) high
reactive power capacitors problems, which in many cases may be a critical
element for various devices - like ICP plasma torches; SMPS converters;
induction heaters; radio transmitters etc. New materials at the markets
allow to solve the problem that at small capacitance - high voltage - high
amperage combination, capacitors have to withstand circulating reactive
power load from kVAR to MVAR range, hence the value of loss factor tan(?) of
the selected insulator material has a critical role, to minimize
overheating. Few designer strategies are disputed, and convincing
experimental data on selected new industrial materials are presented.
Development of the algorithm for implementation of energy-efficient compressed air systems with energy recovery
Authors: Seslija Milan , Reljic Vule , Mladenovic Valentina , Novakovic Miroslav , Jovanovic Zoran
Published: February 2024

In order to improve the energy efficiency of pneumatic systems, this paper
presents an algorithm for the development and implementation of an energy
efficient pneumatic control system with energy recovery of compressed air.
Two different ways of forming closed pneumatic circuits that reuse already
used compressed air are presented. Compared to traditional pneumatic
control, significant energy savings are achieved.
Cell-Surface ZnT8 Antibody Prevents and Reverses Autoimmune Diabetes in Mice
Authors: Kasinathan Devi , Guo Zheng , Sarver Dylan C. , Wong G. William , Yun Shumei , Michels Aaron W. , Yu Liping , Sona Chandan , Poy Matthew N. , Golson Maria L. , Fu Dax
Published: February 2024

Type 1 diabetes (T1D) is an autoimmune disease in which pathogenic lymphocytes target autoantigens expressed in pancreatic islets, leading to the destruction of insulin-producing β-cells. Zinc transporter 8 (ZnT8) is a major autoantigen abundantly present on the β-cell surface. This unique molecular target offers the potential to shield β-cells against autoimmune attacks in T1D. Our previous work showed that a monoclonal antibody (mAb43) against cell-surface ZnT8 could home in on pancreatic islets and prevent autoantibodies from recognizing β-cells. This study demonstrates that mAb43 binds to exocytotic sites on the β-cell surface, masking the antigenic exposure of ZnT8 and insulin after glucose-stimulated insulin secretion. In vivo administration of mAb43 to NOD mice selectively increased the proportion of regulatory T cells in the islet, resulting in complete and sustained protection against T1D onset as well as reversal of new-onset diabetes. The mAb43-induced self-tolerance was reversible after treatment cessation, and no adverse effects were exhibited during long-term monitoring. Our findings suggest that mAb43 masking of the antigenic exposure of β-cells suppresses the immunological cascade from B-cell antigen presentation to T cell–mediated β-cell destruction, providing a novel islet-targeted and antigen-specific immunotherapy to prevent and reverse clinical T1D.

Article Highlights
CD4+ T Cells From Individuals With Type 1 Diabetes Respond to a Novel Class of Deamidated Peptides Formed in Pancreatic Islets
Authors: Callebaut Aïsha , Guyer Perrin , Derua Rita , Buitinga Mijke , Manganaro Anthony , Yi Xiaoyan , Sodré Fernanda Marques Câmara , Vig Saurabh , Suleiman Mara , Marchetti Piero , Eizirik Decio L. , Kent Sally C. , Mathieu Chantal , James Eddie A. , Overbergh Lut
Published: February 2024

The β-cell plays a crucial role in the pathogenesis of type 1 diabetes, in part through the posttranslational modification of self-proteins by biochemical processes such as deamidation. These neoantigens are potential triggers for breaking immune tolerance. We report the detection by LC-MS/MS of 16 novel Gln and 27 novel Asn deamidations in 14 disease-related proteins within inflammatory cytokine–stressed human islets of Langerhans. T-cell clones responsive against one Gln- and three Asn-deamidated peptides could be isolated from peripheral blood of individuals with type 1 diabetes. Ex vivo HLA class II tetramer staining detected higher T-cell frequencies in individuals with the disease compared with control individuals. Furthermore, there was a positive correlation between the frequencies of T cells specific for deamidated peptides, insulin antibody levels at diagnosis, and duration of disease. These results highlight that stressed human islets are prone to enzymatic and biochemical deamidation and suggest that both Gln- and Asn-deamidated peptides can promote the activation and expansion of autoreactive CD4+ T cells. These findings add to the growing evidence that posttranslational modifications undermine tolerance and may open the road for the development of new diagnostic and therapeutic applications for individuals living with type 1 diabetes.

Article Highlights
Antioxidants for Early Treatment of Type 2 Diabetes in Rodents and Humans: Lost in Translation?
Authors: Robertson R. Paul
Published: February 2024

Reactive oxygen species (ROS) are formed by virtually all tissues. In normal concentrations they facilitate many physiologic activities, but in excess they cause oxidative stress and tissue damage. Local antioxidant enzyme synthesis in cells is regulated by the cytoplasmic KEAP-1/Nrf2 complex, which is stimulated by ROS, to release Nrf2 for entry into the nucleus, where it upregulates antioxidant gene expression. Major antioxidant enzymes include glutathione peroxidase (GPx), catalase (CAT), superoxide dismutases (SOD), hemoxygenases (HO), and peroxiredoxins (Prdx). Notably, the pancreatic islet β-cell does not express GPx or CAT, which puts it at greater risk for ROS damage caused by postprandial hyperglycemia. Experimentally, overexpression of GPx in β-cell lines and isolated islets, as well as in vivo studies using genetic models of type 2 diabetes (T2D), has demonstrated enhanced protection against hyperglycemia and oxidative stress. Oral treatment of diabetic rodents with ebselen, a GPx mimetic that is approved for human clinical use, reproduced these findings. Prdx detoxify hydrogen peroxide and reduce lipid peroxides. This suggests that pharmacologic development of more potent, β-cell–specific antioxidants could be valuable as a treatment for oxidative stress due to postprandial hyperglycemia in early T2D in humans.

Article Highlights
Historic Redlining and Impact of Structural Racism on Diabetes Prevalence in a Nationally Representative Sample of U.S. Adults
Authors: Egede Leonard E. , Walker Rebekah J. , Campbell Jennifer A. , Linde Sebastian
Published: February 2024

OBJECTIVE

We investigated direct and indirect relationships between historic redlining and prevalence of diabetes in a U.S. national sample.

RESEARCH DESIGN AND METHODS

Using a previously validated conceptual model, we hypothesized pathways between structural racism and prevalence of diabetes via discrimination, incarceration, poverty, substance use, housing, education, unemployment, and food access. We combined census tract–level data, including diabetes prevalence from the Centers for Disease Control and Prevention PLACES 2019 database, redlining using historic Home Owners’ Loan Corporation (HOLC) maps from the Mapping Inequality project, and census data from the Opportunity Insights database. HOLC grade (a score between 1 [best] and 4 [redlined]) for each census tract was based on overlap with historically HOLC-graded areas. The final analytic sample consisted of 11,375 U.S. census tracts. Structural equation modeling was used to investigate direct and indirect relationships adjusting for the 2010 population.

RESULTS

Redlining was directly associated with higher crude prevalence of diabetes within a census tract (r = 0.01; P = 0.008) after adjusting for the 2010 population (χ2(54) = 69,900.95; P < 0.001; root mean square error of approximation = 0; comparative fit index = 1). Redlining was indirectly associated with diabetes prevalence via incarceration (r = 0.06; P < 0.001), poverty (r = −0.10; P < 0.001), discrimination (r = 0.14; P < 0.001); substance use (measured by binge drinking: r = −0.65, P < 0.001; and smoking: r = 0.35, P < 0.001), housing (r = 0.06; P < 0.001), education (r = −0.17; P < 0.001), unemployment (r = −0.17; P < 0.001), and food access (r = 0.14; P < 0.001) after adjusting for the 2010 population.

CONCLUSIONS

Redlining has significant direct and indirect relationships with diabetes prevalence. Incarceration, poverty, discrimination, substance use, housing, education, unemployment, and food access may be possible targets for interventions aiming to mitigate the impact of structural racism on diabetes.
Enhancing Ecological Footprint Awareness among Academic Staff at Gazi University: A Sustainability Communication Approach
Authors: Durmuş Şenyapar Hafize Nurgül , Ünal Kenan , Kardiyen Filiz
Published: February 2024

Sustainability communication is vital in informing, inspiring, and mobilizing individuals and organizations to take collective actions that contribute to environmental protection, social justice, and economic prosper-ity. A crucial aspect of sustainability, ecological footprint awareness assesses the consciousness of the im-pact of individuals or communities on the environment. This research investigates the level of ecological footprint awareness among academic staff at Gazi University, Turkey, using a comprehensive scale. Find-ings indicate varying levels of awareness across dimensions influenced by gender, marital status, academic title, and income, suggesting potential implications for policymakers and university administrators. The efficacy of sustainability and ecological footprint reduction initiatives can be increased among heteroge-neous cohorts of academic personnel by implementing customized communications and awareness initia-tives. Additional investigation may further elucidate the precise determinants underlying these disparities and scrutinize the most efficacious modes of communication for each faction, thereby augmenting the sus-tainability discourse at Gazi University and in the broader context.
Functional outcomes of accelerated rehabilitation protocol for anterior cruciate ligament reconstruction in amateur athletes: a randomized clinical trial
Authors: Elabd Omar M. , Alghadir Ahmad H. , Ibrahim Abeer R. , Hasan Shahnaz , Rizvi Moattar R. , Sharma Ankita , Iqbal Amir , Elabd Aliaa M.
Published: February 2024

Objective: To determine the impact of the accelerated rehabilitation protocol on knee pain in amateur athletes with anterior cruciate ligament reconstruction (ACLR).
Design: Two-arm, parallel-group randomized comparative design.
Patients: 100 amateur male athletes (mean age22.01±1.79) with ACLR were randomly divided into experimental and control groups (n=50/group).
Methods: An accelerated rehabilitation protocol and a conventional one were used for the experimental group. In contrast, only the conventional rehabilitation protocol was used for the control group in five weekly sessions for twenty-two weeks. The primary outcome measure, knee pain, was measured using the visual analog scale (VAS). Extensive test batteries for hop tests, Knee Injury and Osteoarthritis Outcome Score (KOOS), and knee effusion were measured, aiming to add more objective criteria to determine functional performance.
Results: Both groups (n=50/group) were well-matched (p=0.816), with insignificant differences in their demographic characteristics (p>0.05). MANOVA test showed no significant difference between the two groups (p=0.781) at baseline. A two-way MANOVA of within and between groups' variations indicated overall significant treatment, time, and treatment × time interaction effects (p<0.001) in favor of the accelerated rehabilitation group. Conclusions: The accelerated rehabilitation protocol was more effective in improving functional outcomes than a conventional one in amateur athletes with ACLR.
Wearable Stretch Sensors for Ergonomics-Related Human Movement Monitoring
Authors: Hsu Hsiu-Ling
Published: February 2024

Physical ergonomics has shown to be an effective method of keeping an eye on any illnesses associated with, like, job-related tasks. Wearable sensors and artificial intelligence have been used in conjunction to enhance experimental ergonomic research techniques in the field of physical ergonomics, according to a number of recent studies. This study proposes the Smart Work wear System, a module-based ambulatory system that addresses work-related physical and psychosocial stresses that might impact health and performance. It supports risk assessment, technique training, and workplace design while reducing the requirement for expert trainers and ergonomists. Substituting measurements for observations improves measurement accuracy and repeatability. A modular platform allows for the connection of a variety of sensor types based on the individual requirements of each case.
PERSEPSI UMAT KATOLIK TERHADAP KUALITAS PENDIDIKAN SEKOLAH KATOLIK DI KEVIKEPAN YOGYAKARTA BARAT DAN KEVIKEPAN YOGYAKARTA TIMUR
Authors:   Universitas Sanata Dharma, Yogyakarta, Indonesia, Widiastuti Fransiska Lyra Ayu , Natalie Maria Gratia Lintang ,   Universitas Sanata Dharma, Yogyakarta, Indonesia, Agatha Aurelia Christy ,   Universitas Sanata Dharma, Yogyakarta, Indonesia, Maharani Gabriella ,   Universitas Negeri Yogyakarta, Yogyakarta, Indonesia
Published: February 2024

Perception is a view formed by an individual through information and experience that is received through the process of sensing. In this process, the individual provides an interpretation and assessment of a certain stimulus or object. This research aims to analyze the perceptions of Catholics about the quality of Catholic school education in The Episcopal Vicariate of Yogyakarta. The method that was used in this study is qualitative with a realist approach. Data collection in this study was done with a combination Focus Group Discussion (FGD) with survey form that was given through google Forms which were transmitted to the WhatsApp Group from June to August 2023. The subjects in this study are Catholics who are in 23 parishes in the Episcopal Vicariate of West Yogyakarta and 25 parishes in the Episcopal Vicariate of East Yogyakarta. Catholics who are involved in FGD are those in the parish who have experience with or are involved with Catholic school education, such as parents, students, teachers, or educators, to school employees in the Episcopal Vicariate of West Yogyakarta and the Episcopal Vicariate of East Yogyakarta. Subjects perform FGD using several instrument questions that have been prepared, then the FGD results are recorded into google Forms. The results were analyzed using thematic techniques and found that Catholics in the Episcopal Vicariate of Yogyakarta have a positive perception of Catholic schools. The results of these perceptions also found a mismatch between the positive perception of Catholics and the reality of new admissions data, which decreased in some Catholic schools.
DEWA TERTINGGI “PUANG MATUA” DALAM KEPERCAYAAN ALUK TO DOLO
Authors:   Fakultas Teologi, Universitas Sanata Dharma, Yogyakarta, Indonesia, Saleda Aldry Toban , Bilang Antonius ,   Fakultas Teologi, Universitas Sanata Dharma, Yogyakarta, Indonesia, Ary Rofinus ,   Fakultas Teologi, Universitas Sanata Dharma, Yogyakarta, Indonesia, Widodo Agus ,   Fakultas Teologi, Universitas Sanata Dharma, Yogyakarta, Indonesia
Published: February 2024

Each religious tradition has its own name for Hyang Ilahi. In general, the figure of Hyang Ilahi is commonly referred to as God, Allah, Gusti, dewa, and others. These names indicate the relationship and understanding of a particular society or community towards the Divine Being. This research using qualitative methods through literature study, field observations, and interviews aims to explain the understanding of divinity in Aluk To Dolo Religious tradition, especially the existence of Puang Matua. The results show that the Aluk To Dolo Religious tradition has a divine figure that they worship and praise, namely Puang Matua. Aluk To Dolo adherents always aim for unity with Puang Matua through all the rules of life that have been passed down by Puang Matua as norms that must be obeyed. In addition, they hope to be reunited and live with Puang Matua.
BERAGAMA KATOLIK, BERBUDAYA TIONGHOA SEBUAH KAJIAN TERHADAP HIBRIDITAS UMAT KATOLIK-TIONGHOA PAROKI ST. MARIA IMMACULATA SLAWI
Authors:   Fakultas Teologi, Universitas Sanata Dharma Yogyakarta, Indonesia, Julianto Romario , Lelono Martinus Joko ,   Fakultas Teologi, Universitas Sanata Dharma Yogyakarta, Indonesia
Published: February 2024

Santa Maria Immaculata Slawi Parish stands in the Tegal Regency area which has a history of the development of the Chinese community. Chinese ethnicity plays an important role in the dynamics of the Parish. They simultaneously live Chinese culture and the Catholic faith. As a result of the New Order policies they were unable to live out their culture, but Presidential Decree Number 6 of 2000 and Presidential Decree Number 19 of 2000 opened up space for their cultural expression. On Chinese New Year they start holding toa pek kong or tepekong mutual carnivals. The gotong tepekong ritual is a procession of palanquins containing statues of ancestors that are paraded around the city. This article will explore the appreciation of Chinese Catholics in living out two different traditions. Homi K. Bhabha's thoughts are used to understand the attitude choices of the Chinese-Catholic community in Slawi. In his study, Homi K. Bhabha talks about "third space," the meeting or interaction between two different cultures or identities in the same space. Homi K. Bhabha emphasizes "third space" not only as a result of the meeting between two cultures but also as a dynamic social construction. Analysis of this reality will help understand the complexity of people's meaning of their religious and cultural riches.
Mientras se acaba el mundo. Diálogos políticos en la literatura brasileña del siglo XXI
Authors:   , Gomes de Araujo Rodrigo
Published: February 2024

Se discute cómo la ficción literaria dialoga con su momento histórico a partir del posicionamiento entre las experiencias vivenciadas y las expectativas hacia el futuro. Se cuestiona el actual lugar social de la producción literaria, específicamente de la ficción brasileña. Y para realizar un abordaje se exploran cuatro libros publicados en la segunda década del siglo XXI: Reprodução (2013) de Bernardo Carvalho, O Brasil é bom (2014) de André Sant’Anna, Enterre seus mortos (2018) de Ana Paula Maia y A morte e o meteoro (2019) de Joca Reiners Terron. Estos autores ocupan lugares privilegiados en el escenario de la literatura brasileña reciente y sus obras tienen respaldo de diversos agentes e instituciones, demostrando que la producción ficcional se realiza a partir del diálogo colectivo. Para analizar la actual producción ficcional brasileña, se utiliza un marco teórico-metodológico que asume la literatura como una práctica social, que al mismo tiempo en que tiene su particularidad, también se involucra en discusiones políticas, indisociables de la experiencia histórica.
Hydropolitical potentialities in a post-'Day Zero' Cape Town: "Sensemaking" and the Cape Flats Aquifer
Authors: Wingfield Matthew
Published: February 2024

In the context of the climate crisis, water as a natural resource is under threat globally, and the Global South is of critical interest for political ecological studies. This article argues that environmental crises such as the "Day Zero" drought in 2018 in Cape Town (South Africa) can create possibilities for reformulating the deeply unequal hydropolitics stemming from colonial and apartheid regimes. The drought has enabled the politicisation of underground water, examined through an ethnographic study of a small-scale farming organisation in the Philippi Horticultural Area (PHA) of Cape Town. While tracking ways to secure the protection of natural resources such as aquifers in urban areas, the article further considers how such forms of activism around underground water have sought to "make the invisible, visible," thereby developing more inclusive forms of sensemaking. By providing an analysis of activism taking place during and after a period of acute water scarcity, it contributes to scholarship on emergent political ecological mobilisation in the climate crisis in the Global South.
Information Quality Analysis of YouTube Videos on HIFU for Prostate Cancer: How much is too much?
Authors: Nkansah-Amankra Kwabena , Tutwiler Ameisha , Lash Christopher , Sindhwani Puneet
Published: February 2024

Prostate adenocarcinoma is the most diagnosed cancer among men [1]. This highly prevalent disease in the localized stage is often tackled with either whole gland treatment (radical prostatectomy or radiation) vs. active surveillance [2-4]. However, in recent times there has been a push towards focal therapy with goals of eradicating significant cancer within the prostate while preserving genitourinary function [5,6]. Trans-rectal High-Intensity Focused Ultrasound (HIFU) ablation of prostate tissue) HIFU for prostate cancer, recently approved by the FDA offers patients and providers another treatment option to consider in management of this disease [7]. Thus, it is imperative that information that patients peruse be reliable and of good quality.
Ocular Tuberculosis - Uncommon Presentation in Pediatric Age
Authors: Pinto Mariana Sá , Barros Marta , Fernandes Joana Da Silva
Published: February 2024

Ocular tuberculosis is a clinical challenge due to heterogeneous presentation and difficulty in obtaining ocular samples for microbiology. The incidence is difficult to specify because it is almost exclusively a presumptive diagnosis based on epidemiology and concordant ophthalmologic and systemic findings. The need for a high rate of clinical suspicion and the consequent delay in diagnosis is often responsible for advanced clinical presentations that require a multidisciplinary therapeutic approach. Thus, early onset of therapy is essential to suppress ocular inflammation and prevent progressive and irreversible damage.
Enquête Statistique
Authors: Rédacteur Refuge
Published: February 2024

Répatration approximative des réfugiés à travers le monde
The sonata ballad "Drums of the Great Wall" by Hoang Kyong in the context of Vietnam's artistic culture
Authors: Та К.Ву.
Published: February 2024

Среди композиторов Вьетнама Хоанг Кыонг занимает значимое место. Автор множества сочинений в различных жанрах, на сегодняшний день он во многом создаёт лицо музыкальной культуры европейского типа в своей стране. В числе самых значительных сочинений, созданных Хоанг Кыонгом, соната-баллада "Барабаны Великой стены" для виолончели и фортепиано, написанная под впечатлением поэмы XVIII века "Плач жены воина" синоязычного вьетнамца Данг Чан Кона.
PEMBELAJARAN TARI KREASI MENGGUNAKAN MODEL GROUP INVESTIGATION DI SMAN 1 PRINGSEWU
Authors: Firmansyah Aldi , Setiawan Afrizal Yudha , Adzan Nabilla Kurnia
Published: February 2024

Abstrak Penelitian ini menggunakan metode deskriptif kualitatif. Sumber data dalam penelitian ini adalah guru seni budaya dan siswa kelas XI yang berjumlah 36 orang. Teknik pengumpulan data dilakukan melalui observasi, wawancara, dan dokumentasi. Data dianalisis melalui tiga tahapan yaitu, reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian menunjukkan pada proses pembelajaran tari menggunakan model Group Investigation di SMAN 1 Pringsewu sudah terlaksana sesuai dengan prosedur. Terdapat indikator yang dilakukan dalam pembelajaran tari menggunakan model Group Investigation yaitu (1) pendahuluan (apresepsi); (2) penjelaskan materi pelajaran; (3) pembagian tim dan penjelasan tugas tim; (4) pelaksanaan tugas kelompok; (5) pengawasan oleh guru; (6) presentasi hasil diskusi; (7) pemberian tanggapan terhadap kelompok; (8) membuat kesimpulan; (9) pemberian kuis/tugas individu; (10) evaluasi hasil kerja; (11) pemberian penghargaan dan penutup. Model pembelajaran group investigation di SMA Negeri 1 Pringsewu sebagai hasil belajar individu dalam kelompok dengan krtiteria penilaian siswa mampu melakukan pembelajaran tari dengan adanya peningkatan rasa percaya diri dalam mengemukakan ide, menyusun gerak tari serta berhasil memecahkan suatu permasalahan pembelajaran dengan adanya kerja sama yang dilakukan secara berkelompok. Kata Kunci: Pembelajaran tari, Model pembelajaran kooperatif, Group Investigation  Abstract This study used qualitative descriptive method. The source of data in this study was cultural arts teachers and class XI students totaling 36 people. Data collection techniques are carried out through observation, interviews, and documentation. Data is analyzed through three stages, namely, data reduction, data presentation, and conclusions. The results showed that the dance learning process using the Group Investigation model at SMAN 1 Pringsewu had been carried out in accordance with the indicators. There are indicators carried out in dance learning using the Group Investigation model , namely (1) introduction (reception); (2) explanation of the subject matter; (3) team division and explanation of team tasks; (4) implementation of group tasks; (5) supervision by teachers; (6) presentation of discussion results; (7) responding to the group; (8) make conclusions; (9) the provision of individual quizzes/assignments; (10) evaluation of work results; (11) Awarding and Concluding. Group investigation learning at SMA Negeri 1 Pringsewu as a result of individual learning in groups with assessment criteria students are able to do dance learning with an increase in confidence in expressing ideas, composing dance movements and successfully solving a learning problem with cooperation carried out in groups. Keywords: : Dance learning, Cooperative learning model, Group Investigation
Quasi-degenerate extension of local N-electron valence state perturbation theory with pair-natural orbital method based on localized virtual molecular orbitals
Authors: Hayashi Manami , Saitow Masaaki , Uemura Kazuma , Yanai Takeshi
Published: February 2024

Chemical phenomena involving near-degenerate electronic states, such as conical intersections or avoided crossing, can be properly described using quasi-degenerate perturbation theory (QDPT). This study proposed a highly scalable quasi-degenerate second-order N-electron valence state perturbation theory (QD-NEVPT2) using the local pair-natural orbital (PNO) method. Our recent study showed an efficient implementation of the PNO-based state-specific (SS) NEVPT2 method using orthonormal localized virtual molecular orbitals (LVMOs) as an intermediate local basis. This study derived the state-coupling (or off-diagonal) terms to implement QD-NEVPT2 in an alternative manner to enhance efficiency based on the internally contracted basis (ICB) and PNO overlap matrices between different references. To facilitate further acceleration, a local resolution-of-the-identity (RI) three-index integral generation algorithm was developed using LMOs and LVMOs. Although the NEVPT2 theory is considered to be less susceptible to the intruder-state problem (ISP), this study revealed that it can easily suffer from ISP when calculating high-lying excited states. We ameliorated this instability using the imaginary level shift (LS) technique. The PNO-QD-NEVPT2 calculations were performed on small organic molecules for the 30 lowest-lying states, as well as photoisomerization involving the conical intersection of 1,1-dimethyldibenzo[b,f] silepin with a cis-stilbene skeleton. These calculations revealed that the PNO-QD-NEVPT2 method yielded negligible errors compared to the canonical QD-NEVPT2 results. Furthermore, we tested its applicability to a large photoisomerization system using the green fluorescent protein model and the 10-state calculation of the large transition metal complex, showcasing that off-diagonal elements can be evaluated at a relatively low cost.
Spectral and dynamical properties of multiexcitons in semiconductor nanorods
Authors: Kumar Krishan , Wächtler Maria
Published: February 2024

Understanding multiple charge carrier relaxation dynamics in semiconductor nanocrystals is crucial for utilizing their full potential, as it allows to guide the design of optimized structures. Multiple excitons dynamics often are characterized via the observation of additional fast exponential kinetics at band edge in transient absorption spectroscopy data with increasing excitation intensities. However, these investigations are complicated by the formation of surface localized excitons which also introduce additional fast decay components which could falsely be interpreted as multiexciton kinetics in semiconductor nanocrystals. Another challenge presents the generation of a distribution of species in dependence of the excitation intensity not only including single and double excited systems, but even higher-order multiple excitons. In this study we used intensity dependent transient absorption spectroscopy with broadband probing spanning the whole visible range to identify characteristic spectroscopic signatures for the presence of multiple excitons of varying order in seeded and non-seeded CdS nanorods. Applying an MCMC sampling approach for global target analysis enables us to determine contributions of multiple exciton decay via Auger recombination and population of surface exciton states to the observed transient dynamics. The influence of surface chemistry, i.e., the nature of the surface ligands on multiexciton dynamics of nanorods is studied.
Machine Learning-driven models for predicting CO2 Uptake in Metal-Organic Frameworks (MOFs)
Authors: Achour Sofiene , Hosni Zied
Published: February 2024

This study advances the discourse on the application of machine learning (ML) algorithms for the predictive analysis of CO2 uptake in Metal-Organic Frameworks (MOFs), with a nuanced focus on the CATBoost model's capability to navigate the complexities inherent in MOFs' heterogeneous landscape. Building upon and extending the comparative analysis, our investigation underscores the CATBoost model's remarkable predictive prowess, characterized by a significant reduction in root mean square error (RMSE) and an enhanced R-squared (R²) value, thereby affirming its superior accuracy and reliability in forecasting CO2 adsorption. A pivotal aspect of our research is the integration of SHAP values for a detailed assessment of feature importance, which not only corroborated 'Pressure' and 'Surface Area' as pivotal determinants of CO2 uptake but also illuminated the model's advanced analytical capabilities in handling categorical features and mitigating overfitting, even within a dataset marked by intricate and non-linear patterns. Our quantitative and conceptual analysis, showcasing up to a 15% improvement in (RMSE) over previous models, reveals the CATBoost model’s unparalleled efficiency in discerning the multifaceted interplay of factors influencing CO2 adsorption. This is crucial for the strategic engineering of MOFs with optimized properties. Beyond 'Pressure' and 'Surface Area', our SHAP analysis highlighted other descriptors with substantial values, elucidating their nuanced contributions to CO2 uptake and providing invaluable insights for the MOF design process. Through this work, we aim to foster a deeper understanding and application of ML algorithms in environmental sustainability, thereby building upon the foundational research of Abdi et al. and pushing the boundaries of machine learning applications in the field.
"Eu não sou culpada, de gostar de beber e viver na madrugada"
Authors: Alexandre do Nascimento Uelba
Published: February 2024

Quando falamos de boemia, é frequente associar este mundo aos homens e dificilmente imagina-se as mulheres fazendo parte dele. Mas o mundo da boemia também era vivenciado por mulheres, especialmente as que viviam dele, como as meretrizes, as cantoras profissionais e atrizes do teatro. Dentro deste grupo também incluímos mulheres compositoras que enfrentavam preconceitos diversos para se firmarem num cenário musical ainda fechado para elas. Nosso artigo tem por objetivo analisar o mundo que permeia os sambas e sambas canção, especificamente os de composição da cantora Dora Lopes, entre 1950 e 1962, que mostrassem a relação dela com o mundo boêmio, analisando as representações do amor e relações amorosas/sexuais que as letras de suas canções apresentavam, utilizando os estudos de gênero de Teresa de Lauretis e a noção de dispositivo amoroso/sexual de Tania Navarro Swain para entender como as composições de Dora Lopes quebravam com a lógica de um modelo de relação amorosa/sexual dominante neste cenário musical.
Moldura institucional e projetos de institucionalização do regime militar brasileiro (1964-1978)
Authors: Fico Carlos
Published: February 2024

A ditadura militar consolidou moldura institucional que consistia na convivência de constituições (primeiro a de 1946, depois a de 1967) com legislação excepcional, especialmente os atos institucionais. Tal convivência não expressava uma contradição, tendo sido eficaz para a imposição das chamadas “punições revolucionárias”, ao mesmo tempo que possibilitou aos sucessivos governos militares a busca de um padrão de institucionalização que tinha como fundamento a inclusão em nova constituição de mecanismos de segurança do Estado que realizassem o projeto autoritário de uma “democracia forte”. A convivência entre constituição e legislação excepcional durante a ditadura militar foi possível como decorrência da tradição de intervencionismo militar na história republicana brasileira. O Superior Tribunal Militar (STM), a partir do momento em que passou a julgar civis acusados de crimes políticos, debateu a peculiar moldura institucional da ditadura militar.
Mathematical Symbols in Academic Writing: The Case of Incorporating Mathematical Ideals in Academic Writing for Education Researchers
Authors: Lin Li
Published: February 2024

Mathematical symbols, such as those embodying quantum concepts, are indispensable for conveying complex ideas and relationships in academic writing. However, some education researchers and students keep a distance from anything mathematical: algebraic equations, geometrical reasoning, or statistical symbols. How to lower the access threshold for this type of mathematical narrative and reveal the meanings of a range of quantum conceptions to modern educators thus becomes a real problem. Using the pendulum motion equation as a reference point, I argue in this article for the advantages of academic English or French writing genres that fuse a range of mathematical symbols of quantum concepts and conceptual change. Such writings help demonstrate how incorporating the idea of probability (a) refines the debate among conceptual, verbal, and mathematical academic writing; (b) allows new conceptions that draw on the insights from quantum cognition-supported theories; (c) helps explain students’ understanding of mathematical symbols; and (d) offers a new taxonomy for categorizing academic writings.
Poetic Inquiry as a Reflective Method for Instructors of Academic Writing
Authors: Danielle A. Morris-O’Connor
Published: February 2024

It is important for instructors to reflect on and develop their teaching practices and pedagogy. Using a poetic inquiry method, this article offers an alternative model for reflecting on academic writing and teaching practices using a found poetry cluster. My example focuses on graduate academic writing instruction. I create found poems from my own written reflections and literature on graduate writing and organize them into a cluster to identify connections and dissonances. I finish with a discussion of my critical analysis of the poetry cluster and how using poetic inquiry as a reflective method helped me to develop both my writing process and teaching pedagogy.
An application of autosegmental morphology to some nonconcatenative phenomena in germanic languages
Authors:   , Matthewson Lisa Christine
Published: February 2024

This study is an attempt to apply the theory of autosegmental morphology, as proposed by McCarthy (1979, 1981), to some nonconcatenative phenomena in three languages with otherwise concatenative morphological systems, namely Dutch, German and English.

The main features of the theory of autosegmental phonology, which provides the basis for McCarthy's theory, are described. The literature on autosegmental studies of tone and harmony is reviewed, with particular attention paid to the Well-Formedness Condition, Association Conventions, and the Obligatory Contour Principle. The theory of autosegmental morphology is then introduced, and an application of autosegmental morphology to reduplication, as put forward by Marantz (1982), is detailed.

After a brief discussion of some major differences between the morphological systems of Dutch, German and English on the one hand, and the languages to which autosegmental morphology has so far mainly been applied on the other, attempts are made to apply the theory of autosegmental morphology to the Dutch and German past participle morphemes, a circumfix in Dutch, and reduplication in English and German.

It is found that neither the past participle morphemes nor the Dutch circumfix benefit from an autosegmental treatment. Rather more success results from the reduplication data, and some interesting theoretical issues are discussed in the light of this data.

It is concluded that autosegmental morphology is of use only for those languages, or those parts of languages, which manipulate the skeletal tier. It is further concluded that as the morphologies of Dutch, German and English overwhelmingly do not manipulate the skeletal tier, and as the description of the entire morphologies of these languages autosegmentally would moreover result in some disadvantages, this should not be attempted. Doubt is cast on any implied universality for the theory of autosegmental morphology.
Effects of Neuromuscular Electrical Stimulation in Combination with Glutamine Administration on Skeletal Muscle Atrophy in Colon-26 Tumor-Bearing Mice
Authors: Tatebayashi Daisuke , Himori Koichi , Ashida Yuki , Yamada Takashi
Published: February 2024

The depressed protein synthetic response, a phenomenon termed anabolic resistance, has been shown to be involved in muscle wasting induced by cancer cachexia. Moreover, a positive relationship between the protein synthetic rate and intracellular glutamine (GLN) concentration has been found in skeletal muscles. This study investigated the effects of neuromuscular electrical stimulation (ES) and GLN administration on muscle wasting and GLN metabolism in colon-26 (C-26) tumor-bearing mice. CD2F1 mice were divided into 8 groups: control (CNT), CNT+ES, CNT+GLN, CNT+ES+GLN, C-26, C-26+ES, C-26+GLN, C-26+ES+GLN. Cancer cachexia was induced by subcutaneous injection of C-26 cells and developed for four weeks. ES was performed on the left plantar flexor muscles every other day, and GLN (1 g/kg) was administered daily intraperitoneally starting one day after the C-26 injection. Tumor-free body mass and fast-twitch gastrocnemius (Gas) muscle weight were lower in the C-26 group than in the CNT group (-19% and -17%, respectively). Neither ES training nor GLN administration, alone or in combination, ameliorated the loss of Gas muscle weight in the C-26 mice. However, ES training in combination with GLN administration inhibited the increased expression of GLN synthetase (GS) in the C-26 muscles. Thus, it is likely that GLN plays a critical role in muscle protein metabolism and, therefore, can be targeted as a tentative treatment of cancer cachexia.
Correlation between HBeAg and Hepatitis B Virus DNA and RNA Levels in Diverse Liver Disease Cohorts
Authors: Ma Qian
Published: February 2024

Objective: To investigate the disparities and associations between HBV DNA and HBV RNA in various liver disease groups with respect to HBeAg status. Methods: Between September 2020 and September 2023, 90 patients diagnosed with chronic hepatitis B (CHB), 74 patients diagnosed with liver cirrhosis (LC), and 102 patients diagnosed with hepatocellular carcinoma (HCC) from the Department of Gastroenterology or Infection at the First Affiliated Hospital of Xi’an Jiaotong University were selected. HBV DNA, HBV RNA, and HBeAg quantitative tests were conducted using serum samples from the same patients. Results: In the three groups of cases, the HBV RNA load was higher when HBeAg was positive than when HBeAg was negative, and this difference was statistically significant. Only in the HCC group was the HBV DNA load significantly higher when HBeAg was positive than when HBeAg was negative. Additionally, there was a positive correlation between HBV DNA and HBV RNA regardless of HBeAg status. Conclusion: During HBeAg conversion, HBV RNA demonstrates a more sensitive response than HBV DNA. As CHB progresses to LC or HCC, HBV RNA exhibits better diagnostic value than HBV DNA.
Effect of TSH Suppression Therapy on Sex Hormone Levels after Thyroid Cancer Surgery
Authors: He Shenglin , Su Ya , Zhao Bo , Gao Xudong
Published: February 2024

Objective: To analyze the effect of thyroid-stimulating hormone (TSH) suppression therapy on sex hormone levels in patients undergoing postoperative treatment for thyroid cancer. Methods: A total of 40 patients undergoing postoperative thyroid cancer treatment were selected for data analysis. TSH suppression therapy was implemented during the postoperative period. Patients were grouped according to the TSH level: TSH < 0.1, 0.1 ≤ TSH < 0.5, and TSH ≥ 0.5. Results: Among male patients, there were no significant differences in sex hormone levels at different dosing times and TSH levels (P > 0.05). For female patients, testosterone levels at different dosing times showed no significant differences under the same circumstances (P > 0.05). The comparison of testosterone levels at different TSH levels over 5 years of TSH suppression therapy did not yield significant differences (P > 0.05). However, the comparison of testosterone levels within 5 years of TSH suppression therapy yielded significant differences (P < 0.05), with the lowest levels observed at 0.1 ≤ TSH < 0.5. Conclusion: The use of TSH suppression therapy in postoperative thyroid cancer treatment minimally affects sex hormone levels in male patients. However, it has a significant impact on female patients. Therefore, preoperative sex hormone testing is recommended, and postoperative monitoring should include regular sex hormone testing.
Progress in Investigating the Current Mental Health Status Among Caregivers for Surgical Oncology Patients
Authors: Li Xuefei , Wang Li , Xue Lian , Yang Jian , Cui Shanshan , Tang Shanshan , Fu Cong
Published: February 2024

This article aims to discuss the current state and research progress concerning the mental health of caregivers for surgical oncology patients. The goal is to offer insights that can serve as a reference for further enhancements in caregivers’ mental well-being. This article conducts a comprehensive review and analysis of recent studies on the mental health of caregivers for patients undergoing oncologic surgery. These studies reveal that caregivers commonly grapple with mental health issues, including anxiety, depression, and stress. These problems are closely linked to the stress of the patient’s condition and treatment, the caregiver’s own mental strain, and a lack of social support. In addition, the mental health status of caregivers significantly influences the patient’s treatment and recovery process. Implementing various interventions, such as mental health education, services, the establishment of mental health support teams, and engagement in mental health promotion activities, can contribute to the improvement of caregivers’ mental well-being. This, in turn, has the potential to enhance treatment outcomes and the overall quality of life for patients.
Jianpi Fuzheng Decoction in the Treatment of Gastric Cancer-Related Fatigue
Authors: Liu Weiwei , Qin Xiaobing , Wang Haiyan , Chen Xiao , Liu Yanqing
Published: February 2024

Objective: To observe the clinical effects of Jianpi Fuzheng Decoction in patients with gastric cancer and cancer-related fatigue (CRF). Methods: Using the random number table method as a reference, 68 cases of gastric CRF were randomly divided into two groups. One group served as the control group and received basic treatment, while the other was the observation group. The observation group, in addition to the control group’s treatment, received Jianpi Fuzheng Decoction. The clinical treatment effectiveness, fatigue scores, immune function indicators, and treatment safety were compared between the two groups. Results: The total clinical treatment effectiveness of the observation group and the improvement in immune function indicators after treatment were higher than those of the control group. The fatigue score after treatment was lower in the observation group than in the control group (P < 0.05). No serious adverse reactions occurred during the treatment in either group. Conclusion: Jianpi Fuzheng Decoction can enhance the clinical treatment effectiveness for gastric cancer patients with CRF. It facilitates the acceleration of fatigue symptom improvement and immune function enhancement. The medication’s safety is guaranteed, making it worthy of promotion.
Evaluation of Digits-in-Noise Test and Hearing Handicap Inventory for Adults Screening in Patients with Occupational Noise-Induced Hearing Loss
Authors: Shao Zongzhi
Published: February 2024

Objective: To explore the clinical evaluation role of the Digits-in-Noise (DIN) test and Hearing Handicap Inventory for Adults Screening (HHIA-S) for patients with occupational noise-induced hearing loss and to observe and analyze their application values. Methods: Fifty patients with suspected occupational noise-induced hearing loss were randomly selected from the Department of Otolaryngology at the hospital as the research target. The collection period for the research cases spanned from January 2022 to November 2023, and all patients had a history of noise exposure. The DIN test and HHIA-S were used for hearing examinations, with clinical, comprehensive diagnosis serving as the gold standard to study their diagnostic performance. Results: The compliance rate of the DIN test was 88.00%, the HHIA-S’s compliance rate was 80.00%, and the combined compliance rate was 94.00%. The compliance rate of the DIN test and the combined compliance rates of the patients were statistically significant compared to the clinical gold standard data (P < 0.05), while there was no difference between the compliance rate of the HHIA-S and the gold standard (P > 0.05). The data shows that the sensitivity of the combined diagnosis is significantly higher than the sensitivity data of the DIN test and HHIA-S examination alone (P < 0.05). Its specificity is 100.00%, and the accuracy data of the joint diagnosis in the degree were higher than those of the DIN test alone (P > 0.05) and the HHIA-S alone (P < 0.05). Conclusion: For patients with occupational noise-induced hearing loss, the joint evaluation of the DIN test and HHIA-S can significantly improve their diagnostic value with high sensitivity and accuracy.