bluuebunny/crossref_metadata_2025 huggingface dataset:
Entwicklungspolitisch verursachter Vertreibung begegnen
Authors: Schäfer Dustin
Published: September 2019

Schätzungen gehen derzeit davon aus, dass etwa 20 Millionen Menschen jedes Jahr durch Entwicklungsprojekte vertrieben werden. Der Beitrag geht der Frage nach, inwiefern Beschwerdemechanismen von Entwicklungsbanken zur Verringerung entwicklungspolitisch verursachter Vertreibung beitragen. Es wird angenommen, dass es sich dabei um ein sich zuspitzendes Problem gegenwärtiger Entwicklungszusammenarbeit handelt. Auf Grundlage einer Dokumentenanalyse werden quantitative Trends ermittelt und mit einer qualitativen Fallstudie zum 98. Beschwerdefall des Inspection Panels abgeglichen. Trotz der Einrichtung des Inspection Panels weisen die Trends eindeutig auf eine Zunahme entwicklungspolitisch verursachter Vertreibung hin. Unabhängige Untersuchungen von Beschwerdemechanismen vermögen es jedoch die sozialen und ökologischen Folgen von Entwicklungsprojekten aufzuzeigen und zudem in politisches Handeln auf Seiten der Entwicklungsbanken zu transformieren. Beschwerdemechanismen bieten zudem häufig die einzige Möglichkeit für Projektbetroffene, sich gegen negative Folgen von Entwicklungsprojekten zu wehren.
Im Strom der Entwicklung
Authors: Puk Cora Rebecca
Published: September 2019

Weltweit werden im Namen „der Entwicklung“ Infrastrukturprojekte realisiert, die darauf abzielen, zumindest Teilen der Bevölkerung des Globalen Südens ein an westlichen Standards gemessenes „gutes Leben“ zu ermöglichen. Dies geschieht jedoch sowohl auf Kosten der lokalen Bevölkerung und deren Lebensweisen als auch auf Kosten der Natur. Denn nur durch die Ausweitung des in Lateinamerika seit Jahrzehnten intensivierten Extraktivismus scheint diese „Entwicklung“ möglich. Im Rahmen des Konzepts des „Postextraktivismus“ entstand in den letzten Jahren eine Debatte innerhalb Lateinamerikas, die eine Alternative zu dieser Entwicklung zu skizzieren versucht. Der Artikel fasst zusammen, wie das Konzept des Postextraktivismus nach Gudynas durch das Einbeziehen der Vorstellungen und Ideen lokaler Bevölkerungsgruppen bereichert werden könnte. Das Stauseeprojekt, das im südlichen Chile zu der Enteignung zahlreicher Familien in der Andenregion führte, wird seitens der Regierung(en) mit dem Verweis auf die Notwendigkeit für die Entwicklung des ländlichen Raums legitimiert. Im November 2018 wurden die ersten Häuser der Betroffenen zwangsgeräumt und zerstört. Obwohl dies inzwischen seitens der Justiz als illegal angesehen wird, herrscht in der Gemeinde nach wie vor ein Klima der Unsicherheit. Der Artikel reichert das Konzept des Postextraktivismus um Erkenntnisse aus der Empirie an, welche die Autorin durch ihre Feldforschung 2017 erheben konnte.
Uniform decay rate estimates for the coupled semilinear wave system in inhomogeneous media with locally distributed nonlinear damping
Authors: Almeida A.F. , Cavalcanti M.M. , Gonzalez R.B. , Gonzalez Martinez V.H. , Zanchetta J.P.
Published: September 2019

We consider a coupled semilinear wave system posed in an inhomogeneous medium, with smooth boundary, subject to a nonlinear damping distributed around a neighborhood of the boundary according to the Geometric Control Condition. We show that the energy of the coupled system goes uniformly to zero, for all initial data of finite energy taken in bounded sets of finite energy phase-space. The approach involves refined techniques of microlocal analysis and follows ideas due to Burq and Gérard given in (Burq and Gérard ( 2001 )).
Blow-up results for a semilinear parabolic differential inequality in an exterior domain
Authors: Jleli Mohamed , Samet Bessem
Published: September 2019

We are concerned with a semilinear parabolic differential inequality posed in an exterior domain of [Formula: see text], [Formula: see text]. Some blow-up and existence results are established for the considered problem. The novetly of this paper lies in considering a nontrivial Dirichlet boundary condition, which depends both on time and space. Indeed, to the best of our knowledge, in all articles which deal with the blow-up of solutions in exterior domains, the considered boundary condition is trivial or depends only on space.
Positive solutions of 1-D half Laplacian equation with singular and exponential nonlinearity
Authors: Arora R. , Giacomoni J. , Goel D. , Sreenadh K.
Published: September 2019

In this article, we study the existence, multiplicity, regularity and asymptotic behavior of the positive solutions to the problem of half-Laplacian with singular and exponential growth nonlinearity in one dimension (see below [Formula: see text]). We prove two results regarding the existence and multiplicity of solutions to the problem [Formula: see text]. In the first result, existence and multiplicity have been proved for classical solutions via bifurcation theory while in the latter result multiplicity has been proved for critical exponential nonlinearity by variational methods. An independent question of symmetry and monotonicity properties of classical solution has been answered in the paper. To characterize the behavior of large solutions, we further study isolated singularities for the singular semi linear elliptic equation in [Formula: see text], [Formula: see text] involving exponential growth nonlinearities in the more general framework of [Formula: see text] operator and for all [Formula: see text] (see below [Formula: see text]).
On the degenerate Cahn–Hilliard equation: Global existence and entropy estimates of weak solutions
Authors: Jihui Wu , Shu Wang
Published: September 2019

In this paper, we consider a class of the degenerate Cahn–Hilliard equation with a smooth double-well potential. By applying a semi-discretization technique and asymptotic analysis method on non-degenerate Cahn–Hilliard equation, we obtain the existence and regularity of weak solutions to the Cahn–Hilliard equation with degenerate mobility. Moreover, we define a new entropy and obtain the global entropy estimates.
σ-Evolution models with low regular time-dependent non-effective structural damping
Authors: Vargas Junior Edson Cilos , da Luz Cleverson Roberto
Published: September 2019

In this work we study decay rates for a σ-evolution equation in [Formula: see text] under effects of a damping term represented by the action of a fractional Laplacian operator and a time-dependent coefficient, [Formula: see text]. We consider that b is ‘confined’ in the curve [Formula: see text] for large [Formula: see text] and without any control on [Formula: see text].
MiR-511 mimic transfection inhibits the proliferation, invasion of osteosarcoma cells and reduces metastatic osteosarcoma tumor burden in nude mice via targeting MAPK1
Authors: Wu Junxue , Zhang Chao , Chen Lu
Published: September 2019

Osteosarcoma, a highly aggressive cancer, can rapidly metastasize to distant organs such as lung, liver, brain. Despite much progress in the therapeutic regime has been made, the prognosis of osteosarcoma remains poor. In present study, microRNA-511 (miR-511) is lowly expressed in osteosarcoma cells, including MG63, U-2 OS, Saos-2 cells, while mitogen activated protein kinase1 (MAPK1) is highly expressed in osteosarcoma cells. Interestingly, MAPK1 might be a target of miR-511. We found that overexpression of miR-511 by miR-511 mimic transfection may result to low expression of MAPK1. Further study showed that miR-511 mimic inhibits the development of osteosarcoma MG63 cell, including proliferation and invasion. Moreover, miR-511 mimic transfection reduces metastatic osteosarcoma tumor burden in nude mice. These activities are mediated by targeting MAPK1. Our study provides a new sight for the molecular pathogenesis of osteosarcoma.
Synchronically unexpected /n/ in the Balochi dialect of Iranshahr
Authors: Mahmoudzahi Mousa , Korn Agnes , Jahani Carina
Published: September 2019

Through the passage of time, changes take place in any language. Balochi has experienced historical changes in different layers of its structure. The aim of this article is to describe cases of /n/ in a specific Balochi dialect that are synchronically unexpected because, for instance, the equivalent word in Persian or in other Balochi dialects does not have an /n/, or there are certain forms in the paradigm of a lexeme that do not contain /n/. The focus is on the dialect spoken in and around the regions of Bompur and Iranshahr in Sistan and Baluchestan Province, Iran.

The insertion of unetymological /n/ in words with more than one syllable often causes a change of syllable structure from an open to a closed syllable. It is possible that a preference for closed syllables has got the process of /n/ insertion underway. The reason why /n/ is chosen could be that /n/ is available for nasalization of a vowel. This nasal vowel can then be re-interpreted as VC.
PSORIASIS VULGARIS BERAT DITERAPI MIKOFENOLAT MOFETIL: TANTANGAN DALAM PENGOBATAN
Authors: Darmawan Hari , - Nopriyati
Published: September 2019

Psoriasis merupakan penyakit kulit eritropapuloskuamosa kronik residif, ditandai lesi kulit khas plak eritematosa batas tegas ditutup skuama putih keperakan. Diagnosis psoriasis ditegakkan melalui anamnesis, pemeriksaan fisis, dan histopatologik. Psoriasis vulgaris berat diterapi mikofenolat mofetil (MMF) belum pernah dan baru pertama kali di Rumah Sakit Umum Pusat dr. Mohammad Hoesin Palembang. Pengalaman klinis, efikasi serta keamanan terapi MMF terbatas. Perempuan, 40 tahun, keluhan timbul bintil dan bercak merah meninggi ditutup sisik putih tebal pada hampir seluruh tubuh sejak 8 pekan lalu disertai gatal. Pada status dermatologikus tampak papul-plak eritem, multipel, lentikuler-plakat disertai skuama di regio fasialis, trunkus, ekstremitas anterior et posterior dextra et sinistra. Tanda Auspitz dan fenomena tetesan lilin positif. Biopsi histopatologik mendukung diagnosis psoriasis vulgaris. Skor psoriasis area and severity index (PASI) 20,4 dengan body surface area (BSA) 50%. Pasien diterapi MMF dan steroid topikal selama 12 pekan dan menunjukkan perbaikan PASI 75%, namun dirawat inap kembali dengan drug induced liver injury (DILI).Pilihan MMF karena saat ini metotreksat sulit didapat dan pasien alergi terhadap siklosporin. Perlu penelitian lebih banyak untuk menilai efikasi dan efek samping MMF dalam tatalaksana psoriasis vulgaris. Kata kunci: psoriasis vulgaris berat, mikofenolat mofetil, drug induced liver injury
TERAPI DAPSON PADA PEMFIGOID BULOSA
Authors: Brahmanti Herwinda , Wilanti Nesa Wike , Retnani Diah Prabawati , Rahaju Anny Setijo
Published: September 2019

Pemfigoid bulosa (PB) merupakan penyakit autoimun bulosa subepidermis yang umumnya menyerang orang berusia di atas 70 tahun. Pemfigoid bulosa jarang ditemukan pada usia muda, tetapi penting untuk mempertimbangkan kemungkinan diagnosis PB pada kelompok usia ini. Pemeriksaan imunofluoresen langsung (DIF) bertujuan untuk mengamati deposit linear IgG dan C3 dalam zona membran basalis, terkait diagnosis banding PB dengan penyakit bulosa subepidermis lainnya. Dalam laporan kasus ini, perempuan berusia 26 tahun datang dengan keluhan utama lepuh berdinding tegang yang timbul di atas bercak merah yang gatal pada tungkai, badan, lengan dan wajah, disertai erosi multipel pada lidah dan rongga mulut. Berdasarkan anamnesis, gambaran klinis, pemeriksaan histopatologik, serta pemeriksaan DIF, pasien didiagnosis PB. Terapi ditujukan untuk menekan proses inflamasi, berupa kortikosteroid dan antibiotik. Dapson merupakan antibiotik yang bekerja menekan proses inflamasi, dengan menghambat perlekatan dan kemotaksis neutrofil dan pelepasan mediator inflamasi. Terapi dapson pada laporan kasus ini menghasilkan perbaikan klinis.Kata Kunci: pemfigoid bulosa, dapson
PENINGKATAN ENZIM TRANSAMINASE PADA KUSTA
Authors: Hartanto Felix , Esti Prima Kartika
Published: September 2019

Penyakit kusta adalah penyakit infeksi kronik yang mengenai kulit dan sistem saraf perifer dan disebabkan oleh Mycobacterium leprae, yaitu bakteri tahan asam dan bersifat intraseluler obligat. Seiring berkembangnya ilmu kedokteran saat ini, kusta dianggap sebagai sebuah penyakit sistemik dan organ hepar menjadi salah satu yang terlibat dalam proses patologis penyakit kusta. Komplikasi gangguan fungsi hepar akibat penyakit kusta selama ini kurang mendapat sorotan, padahal gangguan fungsi hepar secara teoritis hampir pasti menyertai setiap penderita kusta, terutama pada saat timbul reaksi ENL. Pada kenyataannya, gangguan fungsi hepar yang ditandai dengan peningkatan enzim transaminase dapat terjadi akibat berbagai penyebab, yaitu efek samping obat yang bersifat hepatotoksik, koinfeksi kusta dengan virus hepatitis, pembentukan granuloma di hepar dari proses patologis penyakit kusta, ataupun akibat dari proses imunologik reaksi ENL yang melibatkan organ hepar.Tulisan ini mencoba untuk mengupas lebih dalam tetang peningkatan enzim transaminase yang terjadi pada penyakit kusta. Pengetahuan tentang hal ini diharapkan dapat memberi manfaat dalam penegakan diagnosis dan mendukung penanganan pasien secara menyeluruh.Kata kunci: kusta, enzim transaminase, eritema nodosum leprosum, drug induced liver injury, granuloma
MELASMA DALAM SUDUT PANDANG GENETIK
Authors: Suryaningsih Betty Ekawati
Published: September 2019

Melasma merupakan kelainan hiperpigmentasi pada wajah dan terdistribusi secara simetris. Lebihbanyak terjadi pada wanita usia reproduktif dan banyak terjadi pada seseorang dengan tipe kulit III-V.Melasma sering memberikan dampak negatif pada kualitas hidup pasien dalam hubungan sosial. Kelainanini sangat sulit diobati dan memerlukan biaya yang cukup mahal, namun sering tidak memuaskan baikbagi pasien maupun dokter yang menanganinya. Patogenesis melasma bersifat multifaktor dan belum dapatdijelaskan sepenuhnya. Faktor genetik, hormon, dan pajanan ultra-violet (UV) merupakan faktor risikomelasma. Dari semua faktor tersebut diduga faktor genetik dan pajanan matahari berperan utama dalampatogenesis melasma. Selain itu riwayat melasma dalam keluarga juga merupakan faktor risiko. Beberapapenelitian terbaru menemukan beberapa ekspresi gen dan melibatkan beberapa jalur yang berperan dalampatogenesis melasma. Gen melanocortin-1 receptor (MC1R) merupakan salah satu gen yang diduga berperansecara genetik pada melasma.Kata kunci: Melasma, genetik, hormonal, pajanan UV dan MC1-R
Gambaran Kejadian Kanker Serviks Di RSUD Ulin Banjarmasin
Authors: Kabuhung Elvine Ivana , Ningrum Novalia Widiya
Published: September 2019

Latar belakang: Kanker serviks adalah keganasan yang terjadi pada serviks disebabkan oleh Human Papiloma Virus (HPV). Insiden kanker serviks semakin mmeningkat. Data dari RSUD Ulin Banjarmasin didapatkan bahwa tahun 2012 hingga tahun 2014 terjadi peningkatan kasus baru penderita knker serviks.Tujuan penelitian: Menggambarkan kejadian kanker serviks di Poli Kandungan RSUD Ulin Banjarmasin.Metode: Penelitian ini merupakan penelitian deskriptif dengan teknik pengambilan sampel yaitu accidental sampling sebanyak 30 orang pasien kanker serviks.Hasil penelitian: Pasien kanker serviks di Poli Kandungan RSUD Ulin Banjarmasin paling banyak pada stadium II dan III, pertama kali melakukan hubungan seksual pada umur < 20 tahun, memiliki paritas multipara, dan memiliki riwayar penggunaan kontrasepsi hormonal.Simpulan: Pasien kanker serviks datang pada stadium lanjut dan kanker serviks ditimbulkan karena perilaku kehidupan yang lalu.Â Kata kunci: Kanker serviksÂ ABSTRACTÂ Background: Cervical cancer is malignancy that occurs in the cervix caused by the Human Papilloma Virus (HPV). The incidence of cervical cancer is increasing. Data from RSUD Ulin Banjarmasin found that in 2012 to 2014 there was an increase in new cases of patients with cervical cancer.Objective: Describe the incidence of cervical cancer in the Poly Womb of RSUD Ulin Banjarmasin.Methods: This research is a descriptive study with sampling techniques namely accidental sampling as many as 30 people with cervical cancer patients.Results: Cervical cancer patients in the Poly Womb of RSUD Ulin Banjarmasin are mostly in stages II and III, first had sexual intercourse at <20 years old, have multipara parity, and has a history of using hormonal contraception. Conclusion: Cervical cancer patients come at an advanced stage and cervical cancer is caused due to past life behavior.Key Word: Cervical Cancer
Studi Literatur Predisposisi Dan Upaya Prevensi Keganasan Kanker Serviks Pada Wanita
Authors: Mardiah Mardiah
Published: September 2019

Kanker serviks menjadi urutan ke 7 dari segi angka kejadian kasus dan urutan ke 8 sebagai penyebab kematian secara global di dunia. Di Indonesia Kanker serviks sendiri menduduki urutan kedua dari 10 kanker yang meyebabkan kematian.Menurut Perkiraan Deperteman Kesehatan RI pada tahun 2013 jumlah wanita penderita kanker serviks sejumlah 98.962 kasus,dan sekitar 90-100 kasus kanker serviks baru terjadi, berarti setiap satu atau dua hari selalu terjadi satu kasus kanker serviks pada wanita. Pusat data dan Informasi Kementrian Kesehatan Republik Indonesia mencatat kejadian kanker serviks pada wanita terus menaglami peningkatan. Kejadian kanker serviks akan sangat mempengaruhi hidup penderitanya dan juga keluarganya serta akan sangat mempengaruhi sektor kesehatan. Terjadinya peningkatan kematian akibat kanker serviks diduga karena keterlambatan penanganan, dikarenakan ketidaktahuan wanita tentang predisposisi dan bagaimana upaya pencegahan kanker serviks dapat dilakukan.Tujuan penulisan ini adalah untuk mengetahui predisposisi kanker servik dan bagaimana upaya prevensi yang dapat dilakukan oleh wanita untuk mencegah terjadinya keganasan kanker serviks. Dengan metode studi literatur berupa jurnal Penelitian Cholifah, et al (2017) Meneliti tentang faktor yang mempengaruhi deteksi kanker serviks,Penelitian Susi, Et al (2017) Persepsi Kanker serviks dan upaya Prevensinya pada perempuan yang memiliki keluarga dengan riwayat kanker, dan telaah buku panduan Penatalaksanaan kanker serviks yang diterbitkan oleh kementrian Kesehatan Republik Indonesia.Kata kunci: Kanker serviks, Predisposisi, PrevensiABSTRACTCervical cancer ranks 7th in terms of number of cases and ranks 8th as a cause of death globally in the world. In Indonesia, cervical cancer ranks second in 10 cancers that cause death. According to the 2013 Ministry of Health's Ministry of Health estimates the number of women with cervical cancer was 98,962 cases, and about 90-100 new cases of cervical cancer occurred, meaning that every one or two days always there is one case of cervical cancer in women. Data and Information Center of the Ministry of Health of the Republic of Indonesia noted the incidence of cervical cancer in women continues to increase. The incidence of cervical cancer will greatly affect the lives of sufferers and their families and will greatly affect the health sector. The occurrence of an increase in deaths from cervical cancer is thought to be due to late treatment, due to ignorance of women about predisposition and how prevention of cervical cancer can be carried out. With the literature study method in the form of the journal Cholifah Research, et al (2017) Examining the factors that influence the detection of cervical cancer, Susi Research, Et al (2017) Perception of Cervical Cancer and Prevention efforts in women who have a family with a history of cancer, and study guidebook Management of cervical cancer published by the Ministry of Health of the Republic of Indonesia.Keywords: Cervical Cancer, Predisposition, Prevention
Analisis Kenaikan Berat Badan Pada Akseptor KB Suntik DI BPM HJ. M
Authors: Hidayah Nurul , Dwisalmarini Desi Lestia
Published: September 2019

Latar Belakang: Program Keluarga Berencana digunakan sebagai salah satu cara untuk menekan pertumbuhan jumlah penduduk. Banjarmasin adalah pengguna kontrasepsi suntik terbanyak. Studi pendahuluan yang saya dilakukan di BPM yaitu dari 10 akseptor kontrasepsi suntik 6 akseptor yang mengalami kenaikan berat badan yaitu 4 pengguna KB suntik 3 bulan dengan lama pemakaian 1,5 tahun dan 2 pengguna akseptor suntik 1 bulan dengan lama pemakaian 2 tahun.Tujuan: Menganalisis kenaikan berat badan pada akseptor KB suntik.Metode: Non eksperimental dengan pendekatan Cross Sectional. Populasi penelitian adalah akseptor kontrasepsi suntik yang menggunakan Cyclofem dan suntik DMPA (Depo Medroxyprogesterone Acetat) di BPM Hj. M dari bulan oktober sampai bulan Desember 2015 berjumlah 188 orang. Jumlah sampelÂ  65 peserta KB Suntik. Teknik sampling menggunakan Purposive Sampling. Pengumpulan data menggunakan angket. Analisis dengan Uji T tidak Berpasangan (P=<0,05).Hasil: Menganalisis kenaikan berat badan pada akseptor KB suntik yaitu rata-rata suntik 1 bulan 1,3 dan suntik 3 bulan 3,8 dengan nilai p <0,001 hasil penelitian ini menunjukan adanya perbedaan kenaikan berat badan suntik 1 bulan dan suntik 3 bulan.Simpulan: Ada perbedaan pengguna kontrasepsi hormonal suntikan dengan kenaikan berat badan.Â  Dalam penelitian ini dapat disimpulkan bahwa pengguna KB suntik 3 bulan lebih besar mengalami kenaikan berat badan dibandingkan suntik 1 bulan.Â Kata Kunci: Berat Badan, Kontrasepsi Hormonal SuntikanAbstract :Background: The Family Planning Program is used as a way to reduce population growth. Banjarmasin is the most injectable contraceptive user. The preliminary study I conducted at BPM was from 10 injectable contraceptive acceptors 6 acceptors who gained weight, namely 4 users of 3-month injection contraception with 1.5 years of usage duration and 2 users of 1-month injection acceptors with 2 years of usage duration.Objective: To analyze weight gain in injection KB acceptors.Method: Non experimental with Cross Sectional approach. The study population was injection contraceptive acceptors who used Cyclofem and injected DMPA (Medroxyprogesterone Acetat Depo) at BPM Hj. M from October to December 2015 amounted to 188 people. The total sample is 65 injecting family planning participants. The sampling technique uses Purposive Sampling. Data collection uses questionnaires. Analysis with the No Paired T Test (P = <0.05).Results: Analyzing the increase in body weight in injectable family planning acceptors, namely 1 month 1.3 injection and 3.8 months injection with 3.8 p values <0.001. The results of this study showed a difference in 1 month injection and 3 month injections.Conclusion: There are differences in injectable hormonal contraceptive users with weight gain. In this study it can be concluded that injecting family planning users 3 months bigger experience weight gain compared to 1 month injection.Keywords: Weight Loss, Hormonal Contraception Injections
Kejadian Retensio Plasenta Berdasarkan Umur Dan Paritas Di RSUD DR. H. Moch Ansari Saleh Banjarmasin
Authors: Dona Sismeri , Meldawati Meldawati , Yayuk Puji
Published: September 2019

Latar Belakang: Sebanyak 558.000 ibu meninggal setiap tahun akibat komplikasi kehamilan dan persalinan, 35% diantaranya adalah meninggal karena perdarahan, penyebab utama pada perdarahan persalinan adalah retensio plasenta , atonia uteri, dan sisa plasenta yang tidak segera ditangani, bahwa 15-20% kematian ibu karena retensio plasenta dan insidennya adalah 0,8-1,2% untuk setiap kelahiran.Tujuan: Menggambarkan Kejadian Retensio Plasenta Berdasarkan Umur dan Paritas di RSUD dr. H. Moch Ansari Saleh Banjarmasinâ€Metode: Penelitian deskriptif adalah metode penelitian yang dilakukan dengan tujuan untuk membuat gambaran atau deskriptif tentang suatu keadaan secara objektif. Populasi dalam penelitian ini adalah seluruh ibu bersalin dengan pervaginam di ruang kebidanan RSUD dr.H. Moch Ansari Saleh Banjarmasin sebanyak 4447 jumlah persalinan. Sampel pada penelitian ini 367 ibu bersalin dengan pervaginam, teknik pengambilan sampel menggunakan teknik probability sampling dengan systematic random sampling.Hasil: Dari 367 ibu bersalin sebanyak 46 orang (12%) mengalami retensio plasenta dari umur yang beresiko <20/>35 tahun ada 37 (10,1%) ibu bersalin dan dari paritas beresiko 1 dan >3 ada 25 (6,8%) ibu bersalin.Â Simpulan : Retensio plasenta banyak terjadi pada ibu dengan paritas dan umur yang tidak beresiko.Kata kunci: Ibu Bersalin, Paritas, Retensio Plasenta, Umur.Â ABSTRACTÂ Â Introduction: As many as 558.000 mother die every year due to complications pregnancy and 35% of them bleeding, the cause of the bleeding delivery is retention the placenta, atonia uteri, and the placental not immediately treated, that 15-20% maternal mortality is because of the placenta and incident retention 0,8-1,2%to live births.Objective: To describe the incidence retained placenta Based on Age and Parity in hospitals dr.H.Moch AnsariSaleh BanjarmasinÂ Methods: Research descriptif is methods of research conducted with the aim to create a picture or descriptive of a situation objectively. The population in this study were all with pervaginam mothers in the obstetrics dr. H. Moch Ansari Saleh Banjarmasin 2016 as many as 4447 deliveries.367 samples in this study with vaginal birth mothers, sampling technik using probability sampling and systematic random sampling.Results: Of the 367 maternal many as 46 people (12%) have been retention the placenta of age at risk <20/>35 years is 37 mother conceives and of parity risk 1 and >3 is 25 mother maternity.Conclusion: Parity and age at risk more than this are not at risk.Keywords: Age, Mother of birth, Parity, Retained Placenta, Mother of birth
Hubungan Usia dan Jenis Kelamin dengan Perilaku Berisiko terkena Infeksi Menular Seksual pada Remaja di Puskesmas Menteng Palangka Raya
Authors: Stefanicia Stefanicia , Oktarina Lelly , Lindarsih Nita Kusuma
Published: September 2019

Â Latar Belakang: Pada masa remaja, banyak terjadi perubahan biologis, psikologis, maupun sosial, dengan masih adanya kejadian kasus infeksi menular seksual yang menjadi bukti bahwa remaja rentan terhadap perilaku berisiko terkena infeksi menular seksual.Tujuan: Penelitian ini bertujuan untuk mengetahui usia, jenis kelamin, dengan perilaku berisiko terkena infeksi menular seksual pada remaja di Puskesmas Menteng Palangka Raya.Metode: Penelitian ini merupakan penelitian observasional analitik dengan rancangan cross sectional. Besar sampel dalam penelitian ini yaitu berjumlah 74 remaja Puskesmas Menteng Palangka Raya dengan metode pengambilan sampel dengan simple random sampling.Hasil: Hasil analisis bivariat penelitian ini menunjukkan bahwa usia dengan perilaku berisiko terkena IMS usia (p=0,000), danÂ  jenis kelamin (p=0,607). Terdapat hubungan usia, dengan perilaku berisiko terkena infeksi menular seksual.Kesimpulan: Berdasarkan Hasil Penelitian maka perlunya menyelenggarakan program, mengevaluasi atau mengaktifkan kembali kegiatan Bimbingan Konseling, PKPR, dengan sasaran remaja maupun orang tuanya, dan membentuk LSM atau konselor khusus yang berkonsentrasi pada remaja.Â Kata kunci : Remaja, perilaku berisiko, infeksi menular seksualÂ Â AbstractÂ Background: During adolescence, there are many biological, psychological, and social changes, with the occurrence of cases of sexually transmitted infections which is evidence that adolescents are vulnerable to risky behavior for sexually transmitted infections.Objective: This study aims to determine the age, sex, and risk behavior of sexually transmitted infections in adolescents at the Menteng Palangka Raya Health Center.Method: This study was an observational analytic study with a cross-sectional design. The sample size in this study was 74 teenagers in the Menteng Palangka Raya Health Center with a simple random sampling method.Results: The results of the bivariate analysis of this study showed that age with risk behavior was affected by age STI (p = 0,000), and gender (p = 0.607). There is a relationship of age, with a risk of sexually transmitted infections.Conclusion: Based on the Research Results, it is necessary to organize a program, evaluate or reactivate the activities of Counseling Guidance, PKPR, targeting youth and their parents, and form a special NGO or counselor that concentrates on youth.Keywords: Teenagers, risk behaviors, sexually transmitted infections
Coarsely Quantized Decoding and Construction of Polar Codes Using the Information Bottleneck Method
Authors: Shah Syed Aizaz Ali , Stark Maximilian , Bauch Gerhard
Published: September 2019

The information bottleneck method is a generic clustering framework from the field of machine learning which allows compressing an observed quantity while retaining as much of the mutual information it shares with the quantity of primary relevance as possible. The framework was recently used to design message-passing decoders for low-density parity-check codes in which all the arithmetic operations on log-likelihood ratios are replaced by table lookups of unsigned integers. This paper presents, in detail, the application of the information bottleneck method to polar codes, where the framework is used to compress the virtual bit channels defined in the code structure and show that the benefits are twofold. On the one hand, the compression restricts the output alphabet of the bit channels to a manageable size. This facilitates computing the capacities of the bit channels in order to identify the ones with larger capacities. On the other hand, the intermediate steps of the compression process can be used to replace the log-likelihood ratio computations in the decoder with table lookups of unsigned integers. Hence, a single procedure produces a polar encoder as well as its tailored, quantized decoder. Moreover, we also use a technique called message alignment to reduce the space complexity of the quantized decoder obtained using the information bottleneck framework.
Deciphering the Symbiotic Plant Microbiome: Translating the Most Recent Discoveries on Rhizobia for the Improvement of Agricultural Practices in Metal-Contaminated and High Saline Lands
Authors: Bellabarba Agnese , Fagorzi Camilla , diCenzo George C. , Pini Francesco , Viti Carlo , Checcucci Alice
Published: September 2019

Rhizosphere and plant-associated microorganisms have been intensely studied for their beneficial effects on plant growth and health. These mainly include nitrogen-fixing bacteria (NFB) and plant-growth promoting rhizobacteria (PGPR). This beneficial fraction is involved in major functions such as plant nutrition and plant resistance to biotic and abiotic stresses, which include water deficiency and heavy-metal contamination. Consequently, crop yield emerges as the net result of the interactions between the plant genome and its associated microbiome. Here, we provide a review covering recent studies on PGP rhizobia as effective inoculants for agricultural practices in harsh soil, and we propose models for inoculant combinations and genomic manipulation strategies to improve crop yield.
MicroRNA-152 Promotes Slow-Twitch Myofiber Formation via Targeting Uncoupling Protein-3 Gene
Authors: Zhang Yong , Yan Honglin , Zhou Pan , Zhang Zhenzhen , Liu Jingbo , Zhang Hongfu
Published: September 2019

The differences of pork quality characteristics among different pig breeds mainly came from the differences in myofiber type compositions. Growing evidence indicated the key role of miRNAs in myofiber specification. In the present study, we found that miR-152 is more abundant in the slow-twitch myofiber-enriched muscles. However, its role in myofiber type transformation and myogenesis is largely unknown. Overexpression of miR-152 in porcine myotubes promoted the formation of slow-twitch myofibers and myogenesis. While, inhibition of miR-152 expression showed the opposite effect to miR-152 mimics transfection. The luciferase reporter analysis confirmed that miR-152 straightly targets the 3′-untranslated region (3’-UTR) of uncoupling protein 3 (UCP3) to cause its post-transcriptional inhibition in the protein level. The knockdown of UCP3 by siRNA showed the similar effect of miR-152 on myofiber type transition. Furthermore, the rescue experiment in the porcine myotube transfected with miR-152 mimics or/and UCP3 overexpression plasmid with or without the 3’UTR revealed that UCP3 mediates the action of miR-152 in slow-twitch myofiber formation. Taken together, our findings proposed a novel molecular mechanism through which miR-152 epigenetically regulates meat quality via promoting slow-twitch myofiber formation and skeletal myogenesis.
A Delphinidin-Enriched Maqui Berry Extract Improves Bone Metabolism and Protects against Bone Loss in Osteopenic Mouse Models
Authors: Nagaoka Masahiro , Maeda Toyonobu , Chatani Masahiro , Handa Kazuaki , Yamakawa Tomoyuki , Kiyohara Shuichi , Negishi-Koga Takako , Kato Yasumasa , Takami Masamichi , Niida Shumpei , Lang Stefanie , Kruger Marlena , Suzuki Keiko
Published: September 2019

In our previous investigation, delphinidin, one of the most abundant anthocyanins found in vegetables and berry fruits, had been shown to inhibit osteoclasts and prevent bone loss in mouse models of osteoporosis. In the present study, we investigated whether a delphinidin glycoside-enriched maqui berry extract (MBE, Delphinol®) exhibits beneficial effects on bone metabolism both in vitro and in vivo. MBE stimulated the osteoblastic differentiation of MC3T3-E1 cells, as indicated by enhanced mineralized nodule formation, and increased alkaline phosphatase activity, through the upregulation of bone morphogenetic protein 2 (Bmp2), runt-related transcription factor 2 (Runx2), Osterix (Osx), osteocalcin (Ocn), and matrix extracellular phosphoglycoprotein (Mepe) mRNA expression. Immunostaining and immunoprecipitation assays demonstrated that MBE suppressed NF-κB transnucleation through acting as a superoxide anion/peroxynitrite scavenger in MC3T3-E1 cells. Simultaneously, MBE inhibited both osteoclastogenesis in primary bone marrow macrophages and pit formation by maturated osteoclasts on dentine slices. Microcomputed tomography (micro-CT) and bone histomorphometry analyses of femurs demonstrated that the daily ingestion of MBE significantly increased BV/TV (ratio of bone volume to tissue volume), Tb.Th (trabecular thickness), Tb.N (trabecular number), N.Nd/N.Tm (node to terminus ratio), OV/TV (ratio of osteoid volume to tissue volume), BFR/TV (bone formation rate per tissue volume), and significantly decreased Tb.Sp (trabecular separation), ES/BS (ratio of eroded surface to bone surface) and N.Oc/BS (number of osteoclast per unit of bone surface), compared to vehicle controls in osteopenic mouse models. These findings suggest that MBE can be a promising natural agent for the prevention of bone loss in osteopenic conditions by not only inhibiting bone resorption, but also stimulating bone formation.
Improving the Reliability of Photovoltaic and Wind Power Storage Systems Using Least Squares Support Vector Machine Optimized by Improved Chicken Swarm Algorithm
Authors: Liu Zhi-Feng , Li Ling-Ling , Tseng Ming-Lang , Tan Raymond R. , Aviso Kathleen B.
Published: September 2019

In photovoltaic and wind power storage systems, the reliability of the battery directly affects the overall reliability of the energy storage system. Failed batteries can seriously affect the stable operation of energy storage systems. This paper aims to improve the reliability of the storage systems by accurately predicting battery life and identifying failing batteries in time. The current prediction models mainly use artificial neural networks, Gaussian process regression and hybrid models. Although these models can achieve high prediction accuracy, the computational cost is high due to model complexity. Least squares support vector machine (LSSVM) is a computationally efficient alternative. Hence, this study combines the improved chicken swarm optimization algorithm (ICSO) and LSSVM into a hybrid ICSO-LSSVM model for the reliability of photovoltaic and wind power storage systems. The following are the contributions of this work. First, the optimal penalty parameter and kernel width are determined. Second, the chicken swarm optimization algorithm (CSO) is improved by introducing chaotic search behavior in the hen and an adaptive learning factor in the chicks. The performance of the ICSO algorithm is shown to be better than CSO using standard test problems. Third, the prediction accuracy of the three models is compared. For NMC1 battery, the predicted relative error of ICSO-LSSVM is 0.94%; for NMC2 battery, the relative error of ICSO-LSSVM is 1%. These findings show that the proposed model is suitable for predicting the failure of batteries in energy storage systems, which can improve preventive and predictive maintenance of such systems.
A Text-Generated Method to Joint Extraction of Entities and Relations
Authors: E Haihong , Xiao Siqi , Song Meina
Published: September 2019

Entity-relation extraction is a basic task in natural language processing, and recently, the use of deep-learning methods, especially the Long Short-Term Memory (LSTM) network, has achieved remarkable performance. However, most of the existing entity-relation extraction methods cannot solve the overlapped multi-relation extraction problem, which means one or two entities are shared among multiple relational triples contained in a sentence. In this paper, we propose a text-generated method to solve the overlapped problem of entity-relation extraction. Based on this, (1) the entities and their corresponding relations are jointly generated as target texts without any additional feature engineering; (2) the model directly generates the relational triples using a unified decoding process, and entities can be repeatedly presented in multiple triples to solve the overlapped-relation problem. We conduct experiments on two public datasets—NYT10 and NYT11. The experimental results show that our proposed method outperforms the existing work, and achieves the best results.
New Algorithm for Rain Cell Identification and Tracking in Rainfall Event Analysis
Authors: He Ting , Einfalt Thomas , Zhang Jianxin , Hua Jiyao , Cai Yang
Published: September 2019

This study proposes a new algorithm termed rain cell identification and tracking (RCIT) to identify and track rain cells from high resolution weather radar data. Previous algorithms have limitations when tracking non-consequent rain cells owing to their use of maximum correlation coefficient methods and their lack of an alternative way to handle the variation stages of rain cells during their life cycles. To address these deficiencies, various methods are implemented in the new algorithm. These include the particle image velocimetry (PIV) method for motion estimation and the rain cell matching rule to obtain the stage changes of rain cells. High resolution (5 min and 1 km) radar data from three rainy days over the German federal state North Rhine Westphalia (NRW) are used in this study. The performance of the identification module for the new algorithm is accessed by two object-oriented verification methods: structure–amplitude–location (SAL) and geometric index, while the performance of the tracking module is compared with TREC and SCOUT tracking algorithms and evaluated by the contingency table verification approach. Results suggest that the performance of the new algorithm is better than reference tracking method. Application of the RCIT algorithm to the selected cases shows that the inner structure of rainfall events in the experimental region present extreme value distributions, with most rainfall events having a short duration with less intensity. The new algorithm can effectively capture the stage changes of rain cells during their life cycles. The proposed algorithm can serve as the basis for further hydro-meteorological applications such as spatial and temporal analysis of rainfall events and short-term flood forecasting.
The Spatiotemporal Dynamics and Socioeconomic Factors of SO2 Emissions in China: A Dynamic Spatial Econometric Design
Authors: Zhou Zhimin
Published: September 2019

With the great strides of China’s economic development, air pollution has become the norm that is a cause of broad adverse influence in society. The spatiotemporal patterns of sulfur dioxide (SO2) emissions are a prerequisite and an inherent characteristic for SO2 emissions to peak in China. By exploratory spatial data analysis (ESDA) and econometric approaches, this study explores the spatiotemporal characteristics of SO2 emissions and reveals how the socioeconomic determinants influence the emissions in China’s 30 provinces from 1995 to 2015. The study first identifies the overall space- and time-trend of regional SO2 emissions and then visualizes the spatiotemporal nexus between SO2 emissions and socioeconomic determinants through the ESDA method. The determinants’ impacts on the space–time variation of emissions are also confirmed and quantified through the dynamic spatial panel data model that controls for both spatial and temporal dependence, thus enabling the analysis to distinguish between the determinants’ long- and short-term spatial effects and leading to richer and novel empirical findings. The study emphasizes close spatiotemporal relationships between SO2 emissions and the socioeconomic determinants. China’s SO2 emissions variation is the multifaceted result of urbanization, foreign direct investment, industrial structure change, technological progress, and population in the short run, and it is highlighted that, in the long run, the emissions are profoundly affected by industrial structure and technology.
Effects of Vitamin D Deficiency on Proliferation and Autophagy of Ovarian and Liver Tissues in a Rat Model of Polycystic Ovary Syndrome
Authors: Lajtai Krisztina , Nagy Csilla Terézia , Tarszabó Róbert , Benkő Rita , Hadjadj Leila , Sziva Réka Eszter , Gerszi Dóra , Bányai Bálint , Ferdinandy Péter , Nádasy György László , Giricz Zoltán , Horváth Eszter Mária , Várbíró Szabolcs
Published: September 2019

Aim: We aimed to examine the alterations of the insulin signaling pathway, autophagy, nitrative stress and the effect of vitamin D supplementation in the liver and ovaries of vitamin D deficient hyperandrogenic rats. Methods: Female Wistar rats received eight weeks of transdermal testosterone treatment and lived on a low vitamin D diet (D–T+). Vitamin D supplementation was achieved by oral administration of vitamin D3 (D+T+). Sham-treated (D+T–) and vitamin D deficient animals (D–T–) served as controls. (N = 10–12 per group). Results: D–T+ animals showed decreased LC3 II levels in the liver and increased p-Akt/Akt and p-eNOS/eNOS ratios with decreased insulin receptor staining in the ovaries. Vitamin D supplementation prevented the increase of Akt phosphorylation in the ovaries. Vitamin D deficiency itself also led to decreased LC3 II levels in the liver and decreased insulin receptor staining in the ovaries. D–T+ group showed no increase in nitrotyrosine staining; however, the ovaries of D–T– rats and the liver of D+T+ animals showed increased staining intensity. Conclusion: Vitamin D deficiency itself might lead to disrupted ovarian maturation and autophagy malfunction in the liver. Preventing Akt phosphorylation may contribute to the beneficial effect of vitamin D treatment on ovarian function in hyperandrogenism.
Hybrid Clustered Nanoparticles for Chemo-Antibacterial Combinatorial Cancer Therapy
Authors: Cortese Barbara , D’Amone Stefania , Testini Mariangela , Ratano Patrizia , Palamà Ilaria Elena
Published: September 2019

Background: A great number of therapeutic limitations, such as chemoresistance, high dosage, and long treatments, are still present in cancer therapy, and are often followed by side effects such as infections, which represent the primary cause of death among patients. Methods: We report pH- and enzymatic-responsive hybrid clustered nanoparticles (HC-NPs), composed of a PCL polymeric core loaded with an anticancer drug, such as Imatinib Mesylate (IM), and coated with biodegradable multilayers embedded with antibacterial and anticancer baby-ship silver NPs, as well as a monoclonal antibody for specific targeting of cancer cells conjugated on the surface. Results: The HC-NPs presented an onion-like structure that serially responded to endogenous stimuli. After internalization into targeted cancer cells, the clustered nanoparticles were able to break up, thanks to intracellular proteases which degraded the biodegradable multilayers and allowed the release of the baby-ship NPs and the IM loaded within the pH-sensible polymer present inside the mothership core. In vitro studies validated the efficiency of HC-NPs in human chronic leukemic cells. This cellular model allowed us to demonstrate specificity and molecular targeting sensitivity, achieved by using a combinatorial approach inside a single nano-platform, instead of free administrations. The combinatory effect of chemotherapic drug and AgNPs in one single nanosystem showed an improved cell death efficacy. In addition, HC-NPs showed a good antibacterial capacity on Gram-negative and Gram-positive bacteria. Conclusions: This study shows an important combinatorial anticancer and antimicrobial effect in vitro.
Altered Levels of Toll-Like Receptors in Circulating Extracellular Vesicles in Multiple Sclerosis
Authors: Bhargava Pavan , Nogueras-Ortiz Carlos , Chawla Sahil , Bæk Rikke , Jørgensen Malene Møller , Kapogiannis Dimitrios
Published: September 2019

Extracellular vesicles (EVs) are involved in inter-cellular communication and their cargo may provide prognostic/diagnostic biomarkers. To discover EV-associated biomarkers for Multiple Sclerosis (MS), we used an immune marker array to identify surface proteins on circulating EVs that differ between MS patients and controls (n = 3 each). We identified toll-like receptor-3 (TLR3) as a potential target for further validation. We utilized prospectively collected serum from relapsing-remitting MS patients (n = 18) and controls (n = 16) and confirmed lower concentration of TLR3 and higher concentration of mechanistically related TLR4 in MS EVs compared to controls. Future studies may further evaluate the utility of EV-associated TLRs as MS biomarkers and uncover their mechanistic significance.
Intracerebral Injection of Extracellular Vesicles from Mesenchymal Stem Cells Exerts Reduced Aβ Plaque Burden in Early Stages of a Preclinical Model of Alzheimer’s Disease
Authors: Elia Chiara A. , Tamborini Matteo , Rasile Marco , Desiato Genni , Marchetti Sara , Swuec Paolo , Mazzitelli Sonia , Clemente Francesca , Anselmo Achille , Matteoli Michela , Malosio Maria Luisa , Coco Silvia
Published: September 2019

Bone marrow Mesenchymal Stem Cells (BM-MSCs), due to their strong protective and anti-inflammatory abilities, have been widely investigated in the context of several diseases for their possible therapeutic role, based on the release of a highly proactive secretome composed of soluble factors and Extracellular Vesicles (EVs). BM-MSC-EVs, in particular, convey many of the beneficial features of parental cells, including direct and indirect β-amyloid degrading-activities, immunoregulatory and neurotrophic abilities. Therefore, EVs represent an extremely attractive tool for therapeutic purposes in neurodegenerative diseases, including Alzheimer’s disease (AD). We examined the therapeutic potential of BM-MSC-EVs injected intracerebrally into the neocortex of APPswe/PS1dE9 AD mice at 3 and 5 months of age, a time window in which the cognitive behavioral phenotype is not yet detectable or has just started to appear. We demonstrate that BM-MSC-EVs are effective at reducing the Aβ plaque burden and the amount of dystrophic neurites in both the cortex and hippocampus. The presence of Neprilysin on BM-MSC-EVs, opens the possibility of a direct β-amyloid degrading action. Our results indicate a potential role for BM-MSC-EVs already in the early stages of AD, suggesting the possibility of intervening before overt clinical manifestations.