bluuebunny/crossref_metadata_2025 huggingface dataset:
A Commonwealth Guide to Ocean Climate Finance: A Guidance Document for Policy-Makers and Ocean Advocates
Authors: Secretariat Commonwealth
Published: June 2023

Drawing from a wide range of resources on ocean climate finance, this guide is intended to support practitioners, policy-makers and ocean advocates to understand the ‘seascape’ of ocean climate finance, and empower them to design and develop more successful ocean climate finance applications. It introduces the special characteristics of ocean-based mitigation and adaptation projects, explains the different sources and types of finance available, and equips readers with a practical understanding of the priorities of different funding groups from both the public and private sectors.

The global ocean is a critically important component of the Earth’s biosphere and climate system, but it faces tremendous threats from the impacts of climate change, including warming, acidification, pollution and development. While the global landscape of climate finance is growing quickly, funding for ocean-based climate mitigation and adaptation projects remains disproportionately small. In this context, the guide provides a clear and practical guide for project design and development, including best practices for securing finance and a wealth of tools and resources for those seeking funding for ocean-based initiatives. These include decision trees to identify the best funding match for your project; checklists for finance applications; and perhaps most importantly, a long-term, strategic approach to project development that is focused on building communities of practice and partnerships between governments, the private sector, public institutions, civil society organisations and communities.

It also includes summaries of funding sources and investment models, as well as case studies and examples of best practice. The guide encourages project proponents to pursue long-term planning for crosscutting projects that deliver multiple integrated goals, both environmental and social. Recognising and addressing the unique features and opportunities of ocean-based projects, and the barriers to them, can contribute to realistic and impactful project design. Furthermore, proactively building partnerships with the private sector allows project proponents to access the largest source of finance in the global economy as well as its associated skills and resources.
Oil and Gas Decommissioning Toolkit: Practical Guidance for Governments
Authors: Secretariat Commonwealth
Published: June 2023

Decommissioning is the final stage of an oil or gas project. At the end of a field’s life, when production has ceased, decommissioning is the process whereby the hydrocarbon reservoirs are isolated and associated infrastructure is removed and disposed of, so that the producing area is left in a safe and environmentally acceptable condition. Decommissioning is a long, costly and complex process, requiring co-operation by the key stakeholders to manage technical, economic, operational, social and environment issues.

It is therefore important that decommissioning is adequately addressed by the government in its capacity as the regulatory authority for the sector.
Realising Article 24 of the Convention on the Rights of Persons with Disabilities: Case Studies in Mainstreaming and Inclusive Education
Authors: Secretariat Commonwealth
Published: June 2023

As part of an ongoing commitment to support the development of a more inclusive education system across Commonwealth countries, the Commonwealth Secretariat commissioned documentation to support good policy and practice, particularly on including students with disabilities in mainstream education. This has been prepared with the objective of initiating a wider dialogue on inclusive practices for mainstreaming disability.
This document provides examples from 11 Commonwealth countries, highlighting the process of change that is underway in these countries and the evolution of policies and strategies to improve access to education for children with disabilities.
It additionally provides models and self-assessment tools to support policy-makers and education professionals as they work towards achieving Sustainable Development Goal (SDG) 4 to ensure inclusive and equitable quality education and promote lifelong learning opportunities for all.
Digital Apps for Nursing the Health Conditions of Pregnant Women, Infants and Young ChildrenDigital Apps for Nursing the Health Conditions of Pregnant Women, Infants and Young Children
Authors: Chakkaravarthini R , Geethalakshmi SN , Subashini P , Dhivyaprabha TT
Published: June 2023

This study summarise the list of digital applications are greatly beneficial to monitor the health conditions of maternal women, neonatal young children
Explicação oral para o ensino de construção de gráficos
Authors: Muniz Rita de Cássia Gonçalves , Guimarães Gilda Lisbôa
Published: June 2023

Este artigo tem como objetivo analisar a explicação oral de professoras do 1º ano do Ensino Fundamental em aulas de construção de gráfico, considerando o domínio conceitual, concepção didática, linguagem oral e gestual das professoras, representações visuais e o contexto da aula (presencial e remota). Observamos que, independente do ambiente (remoto ou presencial), as professoras apresentaram propostas didáticas não desafiadoras e lacunas de domínio conceitual, observadas na linguagem oral e gestual utilizada. O estudo da enunciação da explicação oral contribuiu de maneira fundamental para compreendermos os processos de ensino dos professores, tanto remoto quanto presencial. Acreditamos que, para além de ser uma maneira de investigar o ensino, é importante que nós professores reflitamos sobre o que e como falamos na busca da aprendizagem de nossos alunos.
Editorial #18. Integralidad de funciones universitarias
Authors: Iucci Cecilia
Published: June 2023

Editorial de la revista #18
Entretejiendo miradas: extensión crítica, integralidad y economía feminista
Authors: Assandri Labitte Carla , García Grisoni Mariana , Lindner Yaquinta Mariela
Published: June 2023

En este artículo compartimos algunas reflexiones y orientaciones que han acompañado las prácticas de extensión impulsadas desde la Unidad de Extensión de la Facultad de Ciencias Económicas y Administración en los últimos años. Explicitamos nuestra intención de trabajar desde el modelo de la extensión crítica a sabiendas que en esa senda convivimos y dialogamos con modelos de tipo transferencista. Presentamos nuestras prácticas universitarias desde la perspectiva de la integralidad de funciones, disciplinas y saberes. Finalmente, ensayamos un diálogo entre la extensión crítica y la economía feminista, en un esfuerzo por visibilizar los entramados que hacen a la sostenibilidad de la vida e incorporarlos cómo ámbito de lo económico en nuestro trabajo universitario.
FADU Extensa. Gestión de la integralidad en la Facultad de Arquitectura, Diseño y Urbanismo, Universidad de la República
Authors: Contenti Luis , Lago Guillermo , Rimbaud Tatiana
Published: June 2023

Este artículo presenta una reflexión sobre la gestión de la extensión y la integralidad en la Facultad de Arquitectura, Diseño y Urbanismo de la Universidad de la República desde hace una década y recapitula el proceso de discusión del último año sobre la política de gestión y fomento a la extensión en la Facultad. Se comparte lo actuado en este tiempo desde una mirada crítica y reflexiva y se enumeran los nuevos instrumentos propuestos. Además, se exponen algunos resultados de dichos instrumentos y los desafíos que conlleva en el ámbito de la gestión la puesta en práctica de esas herramientas y propuestas. Las herramientas que se describen fueron ideadas, implementadas y gestionadas por la Comisión Asesora de Extensión y el Servicio de Investigación y Extensión de esta Facultad.
La evaluación educativa como práctica para pensar la integralidad de funciones universitarias
Authors: Rafaghelli Milagros , San Román Candela , Turriani Marianela
Published: June 2023

El artículo presenta reflexiones analíticas respecto de una acción de extensión desarrollada durante el segundo semestre de 2022 entre la Facultad de Ciencias de la Educación de la Universidad Nacional de Entre Ríos y tres institutos superiores de formación docente de distintas localidades de la provincia. Las situaciones problemáticas que se abordaron en la acción se vincularon con un aspecto fundamental en las prácticas docentes, la evaluación. En primer lugar, se presentan la situación y los procesos que movilizaron la construcción y desarrollo del proyecto. En segundo lugar, se plantean las perspectivas teóricas y metodológicas desde las cuales se abordó el mismo, tanto de los enfoques de la extensión en el marco de la integralidad de funciones, como del tema de la evaluación en las instancias de prácticas docentes. Finalmente, se comparten algunas notas distintivas derivadas de la intervención consideradas interesantes para la discusión en cuanto a la integralidad de funciones en la universidad.
Integración e integralidad de funciones sustantivas universitarias con relación a la Educación Sexual Integral. Propuestas desde la Geografía en la Universidad Nacional del Litoral
Authors: Lossio Oscar , Manassero Leticia , Neffen Diego
Published: June 2023

En este artículo se socializan las propuestas de integración y de integralidad de las funciones universitarias de extensión, investigación y docencia, en torno a la articulación de la Geografía con la Educación Sexual Integral, desarrolladas por nuestro equipo en la Universidad Nacional del Litoral, Argentina. Se incluye la definición de integración y de integralidad de las funciones universitarias y la trayectoria del equipo autoral en la temática. Además, se caracteriza la propuesta de ESI en contraposición a los modelos tradicionales de educación sexual y en su relación con la perspectiva de Derechos Humanos. A su vez, se presentan algunas contribuciones específicas de la Geografía a la Educación Sexual Integral, a partir de los desarrollos disciplinares relativos al género y las sexualidades. Por último, se expone un ejemplo de integralidad de funciones universitarias y algunos resultados a partir de las voces de docentes de Geografía de la escuela secundaria.
Reseña / Integración docencia y extensión: otra forma de enseñar y aprender (3)
Authors: Dezar Gimena Valeria Alfonsina
Published: June 2023

Esta publicación es el tercer volumen de una serie de producciones realizadas por el área Incorporación Curricular de la Extensión como parte del Programa de Integración de Funciones de la Secretaría de Extensión y Cultura de la Universidad Nacional del Litoral. El propósito de estas producciones es compartir la experiencia institucional que se está llevando adelante respecto de los procesos de integración de la docencia y la extensión. Se socializan los avances y sentidos construidos durante el tramo de 2017 a 2019 por especialistas, el equipo de gestión y los equipos de Prácticas de Extensión de Educación Experiencial. Aquí se dan a conocer aspectos académicos, políticos, teóricos, pedagógicos, sociales y culturales en los que se sustenta el proceso de integración.
The Minimum Age For Marriage In Law Number 16 Of 2019 Perpective Maqashid Sharia Abdul Majid Al Najjar
Authors: Bahrul Ulum Ahmad , Muslihun
Published: June 2023

This research broadly wants to answer three problem formulations. First, the minimum age requirement for marriage. Second, the minimum age requirement for marriage in law number 19 of 2019. Third, the perspective of Maqasid al-Shari'ah Abdul Majid al-Najjar is the minimum age limit for marriage. By using the theory of Maqasid al-Shari'ah Abdul Majid al-Najjarr so that the right solution will be found regarding the problem within the minimum age limit of marriage. The results of this study indicate that the minimum age limit for marriage, which is 19 years for both men and women, is an appropriate and effective step in achieving universal benefit in the form of becoming an ideal individual. The ideal individual will produce an ideal family, where the ideal family can form an ideal society in the future.
[Penelitian ini berangkat dari perubahan ketentuan batas minimal usia perkawinan dan realitas yang terjadi dalam masyarakat. Pada dasarnya, usia perkawinan bukan merupakah syarat dan rukun dalam perkawinan. Hanya saja, usia perkawinan membuktikan bahwa terdapat kemaslahatan yang akan tercapai dimasa depan apabila dilaksanakan dengan tepat. Adapun tujuan perkawinan sendiri, dimana seharusnya membawa kemaslahatan rupanya tidak dapat tercapai apabila ketentuan pembatasan tersebut tidak dilaksanakan dengan baik. Oleh karena itu, perlu diadakan penelitian supaya didapatkan solusi mengenai permasalahanpermasalahan tersebut. Penelitian ini secara garis besar hendak menjawab tiga rumusan masalah. Pertama, ketentuan usia minimal perkawinan. Kedua, ketentuan usia minimal perkawinan dalam undang-undang no.19 tahun 2019. Ketiga, perspektif Maqasid al-Shari’ah Abdul Majid al-Najjar dalam batas minimal usia perkawinan. Dengan menggunakan metodologi kualitatif dan dengan pendekatan Library Research, maka akan didapatkan datadata verbal mengenai ketentuan batas minimal usia perkawinan. Data yang dikumpulkan kemudian dianalisis menggunakan teori Maqasid al-Shari’ah Abdul Majid al-Najjar sehingga akan ditemukan solusi yang tepat mengenai permasalahan dalam batas minimal usia perkawinan. Hasil penelitian ini menunjukkan bahwa pembatasan usia minimal perkawinan yaitu 19 tahun bagi laki-laki dan perempuan, merupakan langkah yang tepat dan jitu dalam upaya mencapai kemaslahatan universal berupa menjadikan individu yang ideal. Individu yang ideal, akan menghasilkan keluarga yang ideal, dimana keluarga ideal, dapat membentu masyarakat yang ideal pada masa mendatang.]
Penerapan Hybrid Contract dalam Aplikasi BSI Mobile Banking (Analisis Hukum Ekonomi Syariah)
Authors: Hasni Hasniati , Udzma Linda Amala
Published: June 2023

Bank Syariah Indonesia (BSI) adalah lembaga keuangan syariah yang menawarkan kemudahan dalam bertransaksi. Berbagai inovasi produk yang ditawarkan untuk bersaing di dunia perbankan. Produk tersebut berupa media aplikasi yang terhubung dengan jaringan internet dalam menggunakannya. Salah satu produknya yaitu aplikasi BSI Mobile dengan berbagai layanan yang disediakan dari pihak Bank Syariah Indonesia dalam bertransaksi. Aplikasi BSI Mobile menyediakan berbagai fitur dengan menggunakan hybrid contrak dalam penerapannya. Oleh karena itu penelitian ini dilakukan untuk mengetahui hukum penggunaan hybrid contract yang digunakan oleh aplikasi BSI Mobile dalam Islam. Penelitian yang digunakan ialah jenis penelitian literatre review dengan menggunakan pendekatan normative yang dijelaskan secara deskriftif. Teknik pengumpulan data menggunakan data skunder yang diperoeh dari undang-undang, buku, jurnal, artikel ilmiah dan literatur review. Fatwa DSN-MUI telah mengatur hybrid contract yang boleh di lakukan diantaranya yaitu musyarakah mutanaqisah, al-ijarah al-muntahiyah bi al-tamlik, dan mudharabah musytarakah, musyarakah muntahiyah bi al-tamlik. akad-akad tersebut digunakan dalam transaksi aplikasi BSI Mobile. Sehingga penerapan hybrid contract dalam aplikasi BSI mobile sah untuk dilakukan dengan memenuhi rukun dan syarat akad, serta memperhatikan batasan-batasan yang telah ditetapkan oleh syariat Islam.
[Bank Syariah Indonesia (BSI) is a sharia financial institution that offers convenience in transactions. Various product innovations are offered to compete in the banking world. The product is in the form of a media application that is connected to the internet network to use it. One of its products is the BSI Mobile application with various services provided by Bank Syariah Indonesia in transactions. The BSI Mobile application provides various features by implementing a hybrid contract. Therefore this research was conducted to find out the law on the use of hybrid contracts used by the BSI Mobile application in Islam. The research used is a type of literature review research using a normative approach which is explained descriptively. Data collection techniques use secondary data obtained from laws, books, journals, scientific articles, and literature reviews. The DSNMUI fatwa has regulated hybrid contracts that may be carried out, including musyarakah mutanaqisah, al-ijarah al-muntakiyah bi al-tamlik, and mudharabah musytarakah, musyarakah lumpuriyah bi al-tamlik. these contracts are used in BSI Mobile application transactions. So that the application of hybrid contracts in the BSI mobile application is valid to be carried out by fulfilling the pillars and conditions of the contract, and taking into account the limitations set by Islamic law.]
Nothing More than ‘Anti-Cull Activists’: Accusations of Bias and the Politics of Research that Advocates for Non-Human Animals
Authors: Hooper Jes , Aiello Thomas , Hill Kristine , Szydlowski Michelle , Oxley Heaney Sarah
Published: June 2023

This paper explores the ethical quandary faced by researchers whose work advocates for non-human animals and whose results conflict with prevalent anthropocentric societal narratives. To problematise the concept of research bias, we qualitatively analyse contemporary political debates surrounding the treatment of animals to ascertain if, how, when, and by whom research can be conducted with scientific integrity whilst advocating for more ethical treatment of other animals. By taking a holistic approach to the issues of bias presented within the remit of human-animal studies (research concerning human-animal relations), this paper firstly addresses the historic ways in which accusations of bias are interwoven within the animal protection movement. We then explore the ongoing ways in which research concerning animal interests are politically targeted due to the threat such research presents to anthropocentric governing policies and societal practices. Finally, we analyse the legitimate causes of bias represented within the emerging field of human-animal studies. Overall, this paper highlights the pitfalls of research that advocates for animals whilst revealing the actual issues of bias that warrant further attention by the academic community.
Detal i lektura
Authors: Graf Paweł
Published: June 2023

Artykuł ma charakter teoretyczny i prezentuje możliwe sposoby funkcjonowania detalu w tekście oraz związane z detalem strategie lekturowe. Jego celem jest też zarysowanie modelu kontr-tekstu, istniejącego niejako obok tekstu właściwego, powstającego w momencie podążania czytelnika za detalem i niesionymi przez niego kontekstami.
(Nie)wpływowe detale w opowiadaniu
Authors: Talia Domenico
Published: June 2023

Szkic jest wyrazem uznania dla lektury, która dostrzega drobne elementy tekstu, jego świata przedstawionego. Przeciwstawiając sobie czytelnika, podążającego za główną linią opowieści, a zatem zanurzonego w akcję, temu odbiorcy, który się zatrzymuje, by przyglądać się detalom skrytym w fałdach utworu, widzi w tym drugim kogoś, kto w pełni odczuwa literacki sens. Kogoś, kto w dziele potrafi zauważyć analogon życia.
La médiation de textes en tant que compétence. Le cas des étudiants se présentant à l’examen de certification en langue étrangère à l’Université de Varsovie
Authors: Kucharczyk Radosław
Published: June 2023

The purpose of this article is to present the results of empirical research conducted with students taking a foreign language certification test. The aim of the study was to diagnose the extent to which the students interviewed are able to mediate texts. In other words, we wanted to examine whether they possess the knowledge and skills necessary to reconstruct the meanings of a text in order to convey the information imposed by the examination task. The article begins with a short presentation of the notion of mediation. It then discusses the place it has been given in the language classroom by the designers of the CEFR. Finally, we present our empirical study: we define its theoretical framework, present the survey questionnaire we used and then proceed to the analysis of the data collected and the discussion of the results.
Rozwój energetyki obywatelskiej na obszarach wiejskich w Polsce
Authors: Marzec Tomasz
Published: June 2023

Celem pracy jest odpowiedź na pytanie, czy ustawodawca zapewnia wystarczające wsparcie formom organizacyjno-prawnym energetyki obywatelskiej funkcjonującym na obszarach wiejskich. Realizacja tego celu wymaga określenia ram prawnych energetyki obywatelskiej w prawie UE oraz prawie krajowym. Przedstawione rozważania prowadzą do wniosku, że obowiązująca regulacja nie wspiera w dostateczny sposób rozwoju inicjatyw energetyki obywatelskiej. Nie zostały dotychczas wprowadzone przepisy skutecznie zachęcające społeczności rolnicze do realizowania projektów z zakresu OZE oraz zapewniające niezbędne wsparcie finansowe dla tego typu inwestycji. Negatywnie należy ocenić także brak spójności prawodawstwa krajowego w zakresie organizacyjno-prawnych form energetyki obywatelskiej z prawem UE. Ustawodawca powinien sformułować atrakcyjny system zachęt, także finansowych, oraz ograniczyć ryzyko ekonomiczne przeprowadzania społecznej inwestycji w OZE.
Zakłady żywienia zbiorowego – pojęcie, klasyfikacja, status prawny prawny
Authors: Fornalik Aneta
Published: June 2023

Celem rozważań jest ustalenie treści pojęcia „zakłady żywienia zbiorowego”, dokonanie klasyfikacji tych zakładów oraz określenie ich statusu prawnego. Realizując tak określony cel, analizie zostały poddane m.in. pojęcia: „zakład”, „zakład żywienia zbiorowego”, „zakład żywienia zbiorowego typu otwartego”, „zakład żywienia zbiorowego typu zamkniętego” oraz „przedsiębiorstwo spożywcze”. W świetle prawa żywnościowego można wyróżnić zakłady żywienia zbiorowego typu otwartego i zamkniętego. To rozróżnienie jest dość uproszczone, gdyż zakład żywienia zbiorowego typu zamkniętego stanowi jedynie fragment działalności określonej jednostki. W konkluzji Autorka wskazuje m.in. na niejednorodność omawianego pojęcia w porządku prawa krajowego i unijnego, ale także na zróżnicowanie pozostałych pojęć związanych z funkcjonowaniem zakładów żywienia zbiorowego. Objęcie wszystkich zakładów żywienia zbiorowego jedną definicją jest zabiegiem ryzykownym, gdy weźmie się pod uwagę, że każdy z takich zakładów wykazuje pewną swoistość w działalności żywieniowej. Ponadto przepisy prawa żywnościowego nie regulują zasad funkcjonowania poszczególnych jednostek jako zakładów żywienia zbiorowego.
Content teachers’ and lecturers’ corrective feedback in EMI classes in high school and university settings
Authors: Hong Jiye
Published: June 2023

To date, very limited research interest has been given to the strategies English-medium instruction (EMI) teachers or lecturers deploy to provide corrective feedback (CF) on the language use to their students during class interaction. In other words, when EMI teachers incidentally focus on students’ problematic language use, how do they correct it – providing explicit correction or using recast or elicitation? This article reports on a study that examined CF types EMI teachers and lecturers used during classroom discourse, drawing on data collected from classroom observations and recordings of six different EMI classes in high school and university settings in Korea. The frequency and types of CF used in reactive language-related episodes (LREs) were identified in the EMI classes and compared between the two settings and across disciplines (social science, mathematics, and computer science). Findings showed that all the EMI teachers and lecturers offered CF to their students but with different frequency; the schoolteachers offered CF more frequently than the university lecturers. Also, the schoolteachers used more various types of CF than the lecturers. In both settings, CF occurred most frequently in mathematics compared to the other two disciplines. This article ends with suggestions for ways the findings of this study can be used to raise EMI teachers’ awareness of various options for providing CF on students’ linguistic errors during their incidental teaching practices.
Towards a typology of forest-managing organisations around the globe
Authors: Jenke M. , Hintz K.S. , Starfinger M. , Giessen L.
Published: June 2023

The global diversity of forest-managing organisations (FMOs) could, so far, not be captured in a comprehensive framework or terminology leaving the research field fragmented. A typology of FMOs was developed using dimensions drawn from social economy theory to provide a unifying framework
and coherent terminology. FMO types were described according to, (1) the formality of their land ownership and labour relations, (2) their objectives in managing forests, (3) their institutional characteristics, and (4) their participation in the social economy sector. The characteristics
and forest management of each FMO type were reviewed. Additionally, public-private and private-sector partnerships between FMOs were classified. This multidimensional framework enables greater precision in the description and comparison of FMOs and their partnerships. Research hypotheses were
elaborated to encourage future studies on how the characteristics of FMOs could affect the technical and silvicultural aspects of their forest management.
Development and validation of a scale to measure the benefits of Forest Stewardship Council (FSC) certification
Authors: Fagundes C. , Schreiber D. , Nunes M.P. , Fernandes M.E. , Damacena C.
Published: June 2023

This study aimed to present the development and validation of a scale to assess the benefits of FSC certification. A study of this kind was not found in the literature, making the application innovative, especially for the Brazilian context. The variables to compose the scale were built
through a systematic review of the literature, as well as interviews with those responsible for certification in the investigated companies and on-site observation. Further, based on the results of a survey, the scale was validated through principal component analysis. The results revealed
the existence of two factors for the economic dimension and three factors for the social dimension. In conclusion, the scale is an alternative for empirical investigations and applied work in organizations, and can guide measures aimed at enhancing the benefits of certification. Moreover,
as this scale was built following theoretically robust parameters, constitutes a model to be tested in studies with similar characteristics.
Alexander of Aphrodisias’ Theory of Action and the Capacity of Doing Otherwise
Authors: Harari Orna
Published: June 2023

I examine Alexander of Aphrodisias’ theory of action, addressing the question how his view that human actions are determined by reason accounts for the capacity of doing otherwise. Calling into question the standard view that Alexander frees agents from internal determination, I argue that (1) the capacity of doing otherwise is a consequence of determination by reason, since it enables agents to do something different from what they would have done had they followed external circumstances; and (2) this capacity is compatible with causal determination by reason because as a case of potentiality for opposites, it grants agents the qualified possibility of doing otherwise insofar as their nature as human beings is concerned – a possibility which remains also when their actions are causally determined by reason and by their internal disposition. I show further that these elements of Alexander’s theory of action are ultimately based on his conception of the soul, specifically on his commitment to Aristotle’s view that the human soul is not purely rational, as the Stoics hold, but has nonrational and rational parts.
Genetic markers associated with adverse reactions of radioiodine therapy in thyroid cancer patients
Authors: Denisenko Natalia P. , Kachanova Anastasia A. , Sychev Ivan V. , Shuev Gregory N. , Perfilieva Oksana M. , Mukhamadiev Reis H. , Kazakov Ruslan E. , Milyutina Olga I. , Konenkova Olga V. , Ryzhkin Sergey A. , Zhmaeva Elena M. , Kirienko Sergey L. , Ivashchenko Dmitriy V. , Bure Irina V. , Ametov Alexander S. , Poddubnaya Irina V. , Mirzaev Karin B. , Sychev Dmitry A.
Published: June 2023

Objectives

Radioactive iodine therapy is considered for patients with certain clinicopathological factors that predict a significant risk of recurrence, distant metastases of thyroid cancer or disease-specific mortality. The aim of the study was to investigate the association between polymorphisms of genes, products of which are involved in the processes of DNA damage response and autophagy, and the adverse reactions of radioiodine therapy in thyroid cancer patients.

Methods

The study included 181 patients (37 men, 144 women; median age 56 [41; 66.3] years) with histologically confirmed thyroid cancer and a history of thyroidectomy who received radioiodine therapy. NFKB1, ATM, ATG16L2, ATG10, TGFB1, and TNF polymorphisms were determined by allele-specific realtime-PCR.

Results

The frequency of adverse reactions was the following: gastrointestinal symptoms – 57.9 %, local symptoms – 65.8 %, cerebral symptoms – 46.8 %, fatigue – 54.4 %; signs of sialoadenitis six months after radioiodine therapy – 25.2 %. TT genotype carriers of ATG10 rs1864183 had higher frequency of gastrointestinal symptoms (vs. CC+CT), the CC genotype carriers of ATG10 rs10514231 had significantly more frequent cerebral symptoms (vs. CT+TT), as well as AA genotype carriers of TGFB1 rs1800469 (vs. AG+GG). CC genotype of ATG10 rs10514231 increased the incidence of radioiodine-induced fatigue, whereas GA genotype of the ATM rs11212570 had a protective role against fatigue. TGFB1 rs1800469 was associated with signs of sialoadenitis six months after radioiodine therapy.

Conclusions

Genetic factors may contribute to the occurrence of adverse reactions of radioiodine therapy in thyroid cancer patients.
The effect of ubiquitin-specific peptidase 21 on proliferation, migration, and invasion in DU145 cells
Authors: Ma Guoxing , Yang Liyuan , Tang Mingqing , Li Mengjun , Fu Ling , Bao Ying , Zhang Hongxin , Xu Ruian
Published: June 2023

Objectives

Although ubiquitin-specific peptidase 21 (USP21) has been shown to promote the development of various cancers, its role in prostate cancer has been poorly reported. Therefore, this study attempted to investigate the involvement of USP21 in prostate adenocarcinoma (PRAD) progression.

Methods

Information from public databases was used to evaluate the pattern of USP21 expression in PRAD tissues and its effect on patient prognosis. Subsequently, we either upregulated or knocked down USP21 expression in the human PRAD cell line DU145 to assess cell growth, migration, invasiveness, and apoptosis.

Results

The transcript levels of USP21 in PRAD tissues were low, indicating a poor prognosis. In DU145 cells, USP21 silencing impaired cell proliferation, colony formation, cell cycle progression, migratory capacity, and invasiveness, while it increased rates of apoptosis. Furthermore, cell proliferation, migration, and invasion were all induced by upregulating USP21. In addition, gene enrichment analysis revealed that USP21 had the potential to regulate cell adhesion and the cell cycle. This observation was further validated by the detection of expression of related genes in cells with either knockdown or increased USP21 expression levels. The expression and copy numbers of USP21 were significantly correlated with the infiltration levels of immune cells.

Conclusions

Expression level of USP21 is associated with PRAD progression and poor prognosis, and may have a role in potential therapeutic strategies for patients with PRAD.
Excitation wavelength altered PL study of Co doped ZnO nanoparticles suitable for white LED application
Authors: Lavanya N. , Deepak N. K.
Published: June 2023

ZnO nanoparticles doped with Co at different concentration (Zn1−x
Co
x
O) were synthesized by sol–gel auto combustion method and are characterized by using various characterization tools. Structural study using X-ray diffraction technique (XRD) analysis showed the crystalline nature with hexagonal wurtzite geometry and the composition analysis using energy dispersive X-ray spectroscopy (EDX) confirmed the incorporation of Co in the ZnO lattice in the case of doped nanoparticles. Scanning electron-microscopy (SEM) and transmission electron microscopy (TEM) analysis showed the prepared nanoparticles as spherical, loosely agglomerated and having dimension of nanoscale. UV–vis DRS studies indicated a red shift in optical band gap with Co doping. PL spectra exhibits emission in the UV and visible region and the analysis revealed information about the presence of various types of defects in the ZnO lattice. An increase in the excitation wavelength gives intense emission in the high wavelength region for doped nanoparticles confirming the presence of divalent and monovalent oxygen as main defects. The Zn0.93Co0.07O nanoparticles records CIE coordinates lying in the white region of CIE color space at 350 nm with CCT of 5561.4 K suggesting their suitability in fabrication of white light emitting diodes.
III. Regesta decretalium et extravagantes. The Use of Papal Decretals around 1200
Authors: Drossbach Gisela
Published: June 2023

In my paper I will not classify decretal collections on the basis of the letters they include. However, I want to look at the totality of form and content of manuscripts, codicological and paleographical aspects as well as the typology of decretals. My thesis is that they were used in different types of transfer and that the production and spread of decretals happened mainly in the Paris Basin. My article will be presented in the following sections: 1. Introduction; 2. Deconstructibility of Decretals and Extravagants; 3. Materiality and Use of Decretal Collections; 4. Paratexts or “Layout on Page Margins”; 5. Pre-Gratian Decretals; 6. Paris Basin – Use of decretals in Schools; 7. Conclusion
VI. Lutherische Konfessionsbildung. „Lutherische Orthodoxie“ aus rechtshistorischer Sicht
Authors: Schmoeckel Mathias
Published: June 2023

The development of the Lutheran Denomination. “Lutheran Orthodoxy” in the perspective of Legal History. The term ‘Lutheran Orthodoxy’ is mostly used for the majority of Lutherans following the ‘Formular of Concord’ of 1577. Originally, however, the term was coined with a polemic intention to reveal the hardhearted persecution of religious minorities. In a legal perspective it stands for a debate within Saxon Protestants, which starting in 1573 led to the incrimination of Calvinists as well as Philippists (followers of Philipp Melanchthon), but also established, eventually, the Lutheran denomination in the Empire and in other countries. When criminal persecution was no longer to be expected, this kind of debate was carried on among Lutheran lawyers in order to claim true Lutheranism for their own teaching. With Christian Thomasius, however, the repression itself became a reproach – which coins the common perception until today.
VI. Zur Legitimität gentiler Fürsten bei ihren römischen Bürgern
Authors: Liebs Detlef
Published: June 2023

This article addresses the extent to which the Romans living in regions of the Roman Empire conquered by gentile people since the 5th century, regarded their rule by gentile princes as legitimate. The Romans there were generally willing to not just accept them as military victors but also to acknowledge their princes as their masters. In fact many representatives of the upper classes served their new rulers, while the lower classes benefited from a considerably lower tax burden. But resistance occurred when the Vandals attempted to convert their catholic Romans by force to their Arianism.
Die Autobiographie Gustav Hänels in einer Handschrift der Leipziger Universitätsbibliothek – Edition und Kommentar
Authors: Schulz Daniela , Trump Dominik
Published: June 2023

The Autobiography of Gustav Hänel in a Manuscript from the Leipzig University Library – Edition and Commentary. Gustav Hänel (1792–1878) was a law professor in Leipzig, and is still famous for his numerous editions of early medieval Roman law texts. Besides a huge corpus of letters, there is also a handwritten autobiography kept in the Leipzig University Library (Cod. Haen. 58) as part of Hänel’s estate today. This autobiography not only contains personal information, but bears witness to 19th century Europe (and beyond). Since the document has hitherto scarcely been considered by research, an edition is provided here for the first time ever.
Optimierung durch Strukturierung
Authors: Fritz Jürgen
Published: June 2023

Obwohl hochauflösende Sensoren die detaillierte Erfassung von numerischen Produkt- und Prozessparametern erlauben, stellen doch Textdaten den größten Anteil aller verfügbaren Daten in den meisten Unternehmen. Genutzt werden diese Daten viel zu wenig. In diesem Beitrag werden aufgezeigt, welche Möglichkeiten linguistische, statistische Techniken und insbesondere Methoden der Künstlichen Intelligenz im Bereich der Textanalyse bieten und wie diese sich konkret anwenden lassen.
Führung 2030
Authors: Ströhlein Karoline , Kandler Magnus , Ast Jonas , Nyhuis Peter , Lanza Gisela , Nieken Petra
Published: June 2023

Die zunehmende Digitalisierung der Arbeitswelt stellt Mitarbeitende und Führungskräfte vor neue Herausforderungen. Kompetenzanforderungen ändern sich, die Personaleinsatzplanung wird komplexer und ein digitalisiertes Shopfloor Management wird benötigt. In diesem Fachbeitrag werden die Ergebnisse einer Umfrage zu den Themen Kompetenzen, Personaleinsatzplanung und Shopfloor Management vorgestellt. Dabei werden zentrale Faktoren für eine hohe Akzeptanz zur erfolgreichen Durchführung von Shopfloor Management ermittelt. Ein wesentlicher Faktor hierbei ist die Führungskraft und ihre Moderation der Shopfloor-Management-Besprechungen entsprechend der wertebasierten Unternehmenskultur. Welche Kompetenzen hierbei benötigt werden, zeigt dieser Beitrag.
Wertstrommanagement im Zeitalter dynamischer Produktionssysteme
Authors: Frick Nicholas , Reintke Maximilian , Metternich Joachim
Published: June 2023

Um in der Dynamik heutiger Produktionssysteme angemessene Entscheidungen treffen zu können, sind aktuelle Informationen zum Status eines Wertstroms notwendig. Die Datenmengen in Unternehmen führen zu einer Dynamisierung der Produktionsabläufe und zwingen Wertstrommanager:innen zu kurzfristigen und zielgerichteten Anpassungen der Wertströme. Aufgrund des statischen Projektcharakters der konventionellen Wertstrommethode ist eine Weiterentwicklung zu einem dynamischen Managementansatz notwendig. Um diesen digital unterstützen zu können, werden die wichtigsten Aufgaben der Wertstrommanager:innen mithilfe eines Expert:innen-Interviews ermittelt und systematisiert.
Intelligente Kontexterfassung im Automobilumschlag
Authors: Jathe Nicolas , Lütjen Michael , Petzoldt Christoph , Boger Dmitrij , Freitag Michael
Published: June 2023

Eine zentrale Herausforderung bei der Mensch-Technik-Interaktion im Hinblick auf (teil-)autonome Arbeitsumgebungen ist es, ein intuitives Prozessverständnis zur Veranlassung von unterstützenden Aktionen zu schaffen. Im vorliegenden Beitrag wird der Einsatz von am Körper getragenen Bewegungssensoren zur Aktivitätserkennung mit dem übergeordneten Ziel der Prozesserkennung untersucht. Im Ergebnis werden ein Konzept vorgestellt sowie eine exemplarische Umsetzung innerhalb von Lager- und Transportprozessen beim Automobilumschlag evaluiert und diskutiert.
Collection of Experiences: 25 Years’ Work on Seed Propagation of Allochthonous Woody Plants in Skopje and Their Possible Role in the Urban Landscape
Authors: Dimitrova Anastazija , Brndevska Stipanović Viktorija , Kolevska Dana Dina
Published: June 2023

In the past decades, numerous landscaping efforts in the urban and suburban areas of Skopje have provided a diversified presence of allochthonous woody species. From the registered 206 allochthonous woody plants, in the past 25 years, 65 species (19 Gymnospermae and 46 Angiospermae) have been the focus of various research and monitoring efforts, including seed propagation and analysis of the generative propagation potential. Considering the variability in the experimental approach, we have performed an extensive literature revision and combined the results from the two in a summary of species that could be of potential interest in the green infrastructure in Skopje, due to their benefits (ornamental use and air pollution remediation) or risks (invasive and allergenic potential). We have also underlined the potential of using urban species as seed banks and species conservation, along with various services they could provide. To the best of our knowledge, this is the first attempt that summarizes the allochthonous woody species in Skopje along with the experience regarding their generative potential and possible use in urban forestry. As such, it serves as a base for future experimental research that could provide more information about the seed quality and the species’ benefits in Skopje and the surrounding areas.
The illicit trade in antiquities is not the world's third-largest illicit trade: a critical evaluation of a factoid
Authors: Yates Donna , Brodie Neil
Published: June 2023

The claim that the illicit trade in antiquities is the third largest, second only to arms and narcotics, is widely repeated. But where does this claim originate and what is the evidence for its veracity? The authors present a ‘stratigraphic excavation’ of the claim by systematically searching through academic articles, popular press and policy literature to reveal the factoid's use and reuse over the past five decades. The authors find that the claim is not based on any original research or statistics, and it does not originate with any competent authorities. The analysis demonstrates how the uncritical repetition of unsubstantiated ‘facts’ can undermine legitimate efforts to prevent looting, trafficking and illicit sale of antiquities.
Return to Performance Protocols and Criteria Specific to Aerobic Capacity for Aerobic Athletes Who Sustain Lower Extremity Injuries: A Narrative Review
Authors: Choice Erin , Downey Rebecca
Published: June 2023

Return to performance (RTP) protocols vary greatly between sports due to energy system involvement, physical and biomechanical skills, injury type and severity, and varied recommendations from members of the interprofessional care team. Return decisions are guided by clinical reasoning, expert opinion, experience, and sport-specific frameworks. Lower extremity injuries that prevent athletes from continuous aerobic training lead to decreased aerobic capacity upon return, which is linked to increased risk of injury or reinjury. This narrative review compares documented rehabilitation programs and RTP protocols and criteria specific to aerobic capacity for athletes who sustain lower extremity injuries in highly aerobic sports. Databases were searched from 2010 to 2022, yielding 9 primary articles and 11 review articles. No RTP protocol specific to aerobic capacity was identified. Considering the lack of evidence regarding aerobic capacity testing and prescription in RTP protocols, research is necessary to determine the significance of aerobic capacity recommended for RTP. Strength and conditioning coaches should be aware of the decreased aerobic capacity at the time of return, thus the need for additional testing, and implement individualized aerobic conditioning programs to optimize return. .
Stable Neural Population Dynamics in the Regression Subspace for Continuous and Categorical Task Parameters in Monkeys
Authors: Chen He , Kunimatsu Jun , Oya Tomomichi , Imaizumi Yuri , Hori Yukiko , Matsumoto Masayuki , Minamimoto Takafumi , Naya Yuji , Yamada Hiroshi
Published: June 2023

Neural population dynamics provide a key computational framework for understanding information processing in the sensory, cognitive, and motor functions of the brain. They systematically depict complex neural population activity, dominated by strong temporal dynamics as trajectory geometry in a low-dimensional neural space. However, neural population dynamics are poorly related to the conventional analytical framework of single-neuron activity, the rate-coding regime that analyzes firing rate modulations using task parameters. To link the rate-coding and dynamic models, we developed a variant of state-space analysis in the regression subspace, which describes the temporal structures of neural modulations using continuous and categorical task parameters. In macaque monkeys, using two neural population datasets containing either of two standard task parameters, continuous and categorical, we revealed that neural modulation structures are reliably captured by these task parameters in the regression subspace as trajectory geometry in a lower dimension. Furthermore, we combined the classical optimal-stimulus response analysis (usually used in rate-coding analysis) with the dynamic model and found that the most prominent modulation dynamics in the lower dimension were derived from these optimal responses. Using those analyses, we successfully extracted geometries for both task parameters that formed a straight geometry, suggesting that their functional relevance is characterized as a unidimensional feature in their neural modulation dynamics. Collectively, our approach bridges neural modulation in the rate-coding model and the dynamic system, and provides researchers with a significant advantage in exploring the temporal structure of neural modulations for pre-existing datasets.
Open Access for Open Science
Authors: Pulverer Bernd
Published: June 2023

The EMBO Journal and EMBO Reports join EMBO Molecular Medicine, Molecular Systems Biology and Life Science Alliance as Open Access journals from 2024. Full Open Access at EMBO Press completes another step towards the goal of an integrated Open Science approach for the dissemination of highly selected and curated science.
Editorial
Authors: Engelbrecht Lambert K
Published: June 2023

This second edition in 2023 of Social Work/Maatskaplike Werk offers eight articles with themes centred on social work during the hitherto unknown Covid-19 pandemic, child protection, supervision in different contexts and substance abuse respectively.