bluuebunny/crossref_metadata_2025 huggingface dataset:
A Comparison of Pseudorabies Virus Latency to Other α-Herpesvirinae Subfamily Members
Authors: Chen Jing , Li Gang , Wan Chao , Li Yixuan , Peng Lianci , Fang Rendong , Peng Yuanyi , Ye Chao
Published: June 2022

Pseudorabies virus (PRV), the causative agent of Aujeszky’s disease, is one of the most important infectious pathogens threatening the global pig industry. Like other members of alphaherpesviruses, PRV establishes a lifelong latent infection and occasionally reactivates from latency after stress stimulus in infected pigs. Latent infected pigs can then serve as the source of recurrent infection, which is one of the difficulties for PRV eradication. Virus latency refers to the retention of viral complete genomes without production of infectious progeny virus; however, following stress stimulus, the virus can be reactivated into lytic infection, which is known as the latency-reactivation cycle. Recently, several research have indicated that alphaherpesvirus latency and reactivation is regulated by a complex interplay between virus, neurons, and the immune system. However, with those limited reports, the relevant advances in PRV latency are lagging behind. Therefore, in this review we focus on the regulatory mechanisms in PRV latency via summarizing the progress of PRV itself and that of other alphaherpesviruses, which will improve our understanding in the underlying mechanism of PRV latency and help design novel therapeutic strategies to control PRV latency.
Drug Discovery Study Aimed at a Functional Cure for HBV
Authors: Watanabe Takehisa , Hayashi Sanae , Tanaka Yasuhito
Published: June 2022

Hepatitis B virus (HBV) causes acute and, most importantly, chronic hepatitis B worldwide. Antiviral treatments have been developed to reduce viral loads but few patients with chronic hepatitis B (CHB) achieve a functional cure. The development of new therapeutic agents is desirable. Recently, many novel agents have been developed, including drugs targeting HBV-DNA and HBV-RNA. This review provides an overview of the developmental status of these drugs, especially direct acting antiviral agents (DAAs). Serological biomarkers of HBV infection are essential for predicting the clinical course of CHB. It is also important to determine the amount and activity of covalently closed circular DNA (cccDNA) in the nuclei of infected hepatocytes. Hepatitis B core-associated antigen (HBcrAg) is a new HBV marker that has an important role in reflecting cccDNA in CHB, because it is associated with hepatic cccDNA, as well as serum HBV DNA. The highly sensitive HBcrAg (iTACT-HBcrAg) assay could be a very sensitive HBV activation marker and an alternative to HBV DNA testing for monitoring reactivation. Many of the drugs currently in clinical trials have shown efficacy in reducing hepatitis B surface antigen (HBsAg) levels. Combination therapies with DAAs and boost immune response are also under development; finding the best combinations will be important for therapeutic development.
Prioritization of Vaccines for Inclusion into China’s Expanded Program on Immunization: Evidence from Experts’ Knowledge and Opinions
Authors: Ma Chao , Li Junhong , Wang Nan , Wang Yamin , Song Yudan , Zeng Xiang , Zheng Canjun , An Zhijie , Rodewald Lance , Yin Zundong
Published: June 2022

Background: Vaccine developers in China have made an increasing number of infectious diseases preventable through vaccination. An appropriate decision-making procedure is necessary for making wise decisions on whether to introduce new vaccines into the Expanded Program on Immunization (EPI). When there are several vaccines that could potentially be considered, a scientifically justifiable mechanism is needed for prioritizing and sequencing vaccines for consideration. Methods: We used a modified Delphi technique (MDT) to develop and refine an indicator system to prioritize vaccines and make policy recommendations concerning their introduction into China’s EPI system. From January through May 2021, thirty-nine experts were recruited and participated in a two-round Delphi survey that was based on a set of candidate indicators obtained through a literature review and reference to the WHO vaccine introduction recommendations. Using the resulting indicator system, we conducted a third consultation with a multi-disciplinary group of experts who scored five program-eligible candidate vaccines to determine prioritization and sequencing for consideration of inclusion into the EPI. Results: Response rates of the thirty-nine experts were 100% and 97.4% across the two rounds. Authority coefficients from rounds one to three were over 0.70, reflecting the high accuracy and reliability of the consultation. Coordination coefficients of importance scores for primary, secondary, and tertiary indicators were 0.486, 0.356, 0.275 in round one, and 0.405, 0.340, and 0.236 in round two. According to the scores from 30 experts using our indicator system, the sequence and scores (1–10 scale, 10 highest) of 5 candidate vaccines were varicella (6.91), meningococcal conjugate AC (6.83), Hib (6.74), influenza (6.56), and EV71 (6.17) vaccines. Conclusions: A modified Delphi technique effectively built a scientific, rational, comprehensive, and systematic indicator system for prioritizing vaccine candidates for consideration of inclusion into the EPI. The rank order will be used by the technical working groups of China’s National Immunization Advisory Committee to sequentially develop and present Evidence-to-Recommendation tables for making policy recommendations.
Acquired Thrombotic Thrombocytopenic Purpura Following Inactivated COVID-19 Vaccines: Two Case Reports and a Short Literature Review
Authors: Ben Saida Imen , Maatouk Iyed , Toumi Radhouane , Bouslama Emna , Ben Ismail Hajer , Ben Salem Chaker , Boussarsar Mohamed
Published: June 2022

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak in December 2019, causing millions of deaths all over the world, and the lack of specific treatment for severe forms of coronavirus disease 2019 (COVID-19) have led to the development of vaccines in record time, increasing the risk of vaccine safety issues. Recently, several cases of thrombotic thrombocytopenic purpura (TTP) have been reported following COVID-19 vaccination. TTP is a rare disease characterized by thrombocytopenia, microangiopathic hemolytic anemia and ischemic end-organ lesions. It can be either congenital or acquired. Various events such as viral infections, medication, pregnancy, malignancies, and vaccinations may cause TTP. Here, we report two cases of acquired TTP following Sinopharm COVID-19 vaccine (BBIBP-CorV) and Sinovac COVID-19 vaccine (CoronaVac). Diagnosis was based on clinical presentation and confirmed with a severe reduction in the activity of von Willebrand factor-cleaving protease ADAMTS-13 and the presence of inhibitory autoantibodies. The two patients were successfully treated with corticosteroids, plasma exchange therapy and rituximab in the acute phase. In the literature, the reported cases of TTP induced by COVID-19 vaccination occurred after Adenoviral Vector DNA- and SARS-CoV-2 mRNA-Based COVID-19 vaccines. To the best of our knowledge, this is the first report of acquired TTP after inactivated virus COVID-19 vaccination.
Safety and Immunogenicity of Inactivated Bacillus subtilis Spores as a Heterologous Antibody Booster for COVID-19 Vaccines
Authors: Sung Johnny Chun-Chau , Lai Nelson Cheuk-Yin , Wu Kam-Chau , Choi Man-Chung , Ma Chloe Ho-Yi , Lin Jayman , Kuok Cheong-Nang , Leong Wai-Leng , Lam Weng-Kei , Hamied Yusuf Khwaja , Lam Dominic Man-Kit , Sze Eric Tung-Po , Kwong Keith Wai-Yeung
Published: June 2022

The coronavirus diseases 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections have threatened the world for more than 2 years. Multiple vaccine candidates have been developed and approved for emergency use by specific markets, but multiple doses are required to maintain the antibody level. Preliminary safety and immunogenicity data about an oral dose vaccine candidate using recombinant Bacillus subtilis in healthy adults were reported previously from an investigator-initiated trial in Hong Kong. Additional data are required in order to demonstrate the safety and efficacy of the candidate as a heterologous booster in vaccinated recipients. In an ongoing, placebo-controlled, observer-blinded, fixed dose, investigator-initiated trial conducted in the Macau, we randomly assigned healthy adults, 21 to 62 years of age to receive either placebo or a Bacillus subtilis oral dose vaccine candidate, which expressed the spike protein receptor binding domain of SARS-CoV-2 on the spore surface. The primary outcome was safety (e.g., local and systemic reactions and adverse events); immunogenicity was a secondary outcome. For both the active vaccine and placebo, participants received three courses in three consecutive days. A total of 16 participants underwent randomization: 9 participants received vaccine and 7 received placebo. No observable local or systemic side-effect was reported. In both younger and older adults receiving placebo, the neutralizing antibody levels were gradually declining, whereas the participants receiving the antibody booster showed an increase in neutralizing antibody level.
Development and Comparison of Water Quality Network Model and Data Analytics Model for Monochloramine Decay Prediction
Authors: Hossain Sharif , Hewa Guna A. , Chow Christopher W. K. , Cook David
Published: June 2022

The conventional drinking water treatment process involves disinfecting water at the final stage of treatment to ensure water is microbiologically safe at customer taps. Monochloramine is a popular disinfectant used in many water distribution systems (WDSs) worldwide. Understanding the factors that impact monochloramine decay in the WDS is critical for maintaining disinfection at the customer tap. While monochloramine residue moves through a WDS, it decays via several pathways including chemical, microbiological, and wall decay processes. The decay profile in these pathways is often site-specific and depends on various factors including treated water characteristics. In a water quality network model, the decay of a chemical species is often modelled using two parameters that represent bulk and wall decay kinetics. Typical bulk decay characteristics of monochloramine for a specific WDS can be easily established in the laboratory using grab sample tests, while in a real situation, wall decay is difficult to quantify. In this study, we compared two different approaches to model monochloramine decay in a WDS. In the first approach, the wall decay parameter was quantified using a parameter optimisation technique with monochloramine concentrations at different network locations simulated using a water quality network model. In the second approach, a data analytics model was developed using a machine learning algorithm. For both approaches, the model predicted monochloramine concentrations closely matched the observed data. Our study suggests that the data analytics model has a relatively higher accuracy in predicting monochloramine residual concentrations in a WDS.
In Search of Periodicity in the Annual Precipitation in Europe (1881–2020)
Authors: Walanus Adam , Twardosz Robert , Cebulska Marta , Płachta Arkadiusz
Published: June 2022

A new method of searching for periodicity has been developed on the basis of extensive spatio-temporal data. The result, however, produces little more than doubts. The standard Fourier analysis indicates some periods, namely 3.7-, 7.0-, 8.8-, and 17.5-year periods, and these periodic signals are distributed relatively consistently over some regions of Europe. However, the expectations that the exact harmonic 8.8 years of 17.5 years, and not so exact 3.7 years of 7.0 years will be present at the same or close stations are not fulfilled.
Multi-Location Emulation of a Process-Based Salinity Model Using Machine Learning
Authors: Qi Siyu , He Minxue , Bai Zhaojun , Ding Zhi , Sandhu Prabhjot , Zhou Yu , Namadi Peyman , Tom Bradley , Hoang Raymond , Anderson Jamie
Published: June 2022

Advances in machine-learning techniques can serve practical water management needs such as salinity level estimation. This study explores machine learning, particularly deep-learning techniques in developing computer emulators for a commonly used process model, the Delta Simulation Model II (DSM2), used for salinity estimation in California’s Sacramento-San Joaquin Delta (Delta). We apply historical daily input data to DSM2 and corresponding salinity simulations at 28 study locations from 1990 to 2019 to train two machine-learning models: a multi-layer perceptron (MLP) and Long-Short-Term Memory (LSTM) networks in a multi-task learning framework. We assess sensitivity of both networks to the amount of antecedent input information (memory) and training data to determine appropriate memory size and training data length. We evaluate network performance according to several statistical metrics as well as visual inspection. The study further investigates two additional networks, the Gated Recurrent Unit (GRU) and Residual Network (ResNet) in salinity modeling, and compares their efficacy against MLP and LSTM. Our results demonstrate strong performance of the four neural network models over the study period, achieving absolute bias below 4%, plus near-perfect correlation coefficients and Nash–Sutcliffe efficiency coefficients. The high complexity LSTM shows slight performance edge. We further show that deeper and wider versions of MLP and LSTM yield only marginal benefit over their baseline counterparts. We also examined issues related to potential overfitting by the proposed models, training data selection strategies, and analytical and practical implications. Overall, this new study indicates that machine-learning-based emulators can efficiently emulate DSM2 in salinity simulation. They exhibit strong potential to supplement DSM2 in salinity modeling and help guide water resource planning and management practices for the Delta region.
Effects of Weather Extremes on the Nutrient Dynamics of a Shallow Eutrophic Lake as Observed during a Three-Year Monitoring Study
Authors: Zeman-Kuhnert Sebastian , Thiel Volker , Heim Christine
Published: June 2022

The formation of algal and cyanobacterial blooms caused by the eutrophication of water bodies is a growing global concern. To examine the impact of extreme weather events on blooms, eutrophication-related parameters (e.g., water temperature, nitrate, ammonium, nitrite, and soluble reactive phosphate (SRP)) were quantitatively assessed monthly over three years (2017–2019) at Lake Seeburg (Central Germany), a shallow eutrophic lake with regular cyanobacterial blooms. In addition, SRP concentrations in sediment pore water were assessed monthly for one year (2018). The monitoring period included a three-day extremely heavy rain event in 2017 as well as a severe drought in summer 2018. No such extreme weather conditions occurred in 2019. After the heavy rain event in 2017, anoxic water containing high levels of ammonium and SRP entered the lake from flooded upstream wetlands. This external nutrient spike resulted in a heavy but short (3 weeks) and monospecific cyanobacterial bloom. A different situation occurred during the exceptionally hot and dry summer of 2018. Especially favored by high water temperatures, SRP concentrations in sediment pore waters gradually increased to extreme levels (34.4 mg/L). This resulted in a strong and sustained internal SRP delivery into the water column (69 mg/m2·d−1), which supported the longest-lasting cyanobacterial bloom (3 months) within the three-year monitoring period. Subsequent biomass decay led to oxygen-depleted conditions in the bottom waters, elevated ammonium, and, later, nitrate concentrations. Our observations demonstrate the particular effects of extreme weather events on nutrient dynamics and the phytoplankton composition in the lake. As the frequency and intensity of such events will likely increase due to climate change, their impacts need to be increasingly considered, e.g., in future remediation strategies.
Interaction of Irregular Distribution of Submerged Rigid Vegetation and Flow within a Straight Pool
Authors: Nosrati Kourosh , Afzalimehr Hossein , Sui Jueyi
Published: June 2022

The interaction of bedform and vegetation cover significantly affects the turbulent flow parameters. To investigate this interaction, experiments were carried out in both a gravel-bed river and a laboratory flume. The purpose of field investigations was to find the slopes for both the entrance section and exit section of pools, the grain size of the bed material, and the flow condition. Based on field data, without considering any scaling analysis, a straight pool was constructed in a laboratory flume that was 0.9 m wide, 0.6 m deep, and 14 m long. The entry and exit slopes of the straight pool were 7.4° and 4°, respectively. The straight pool had vertical side walls and a gravel bed with a median grain size of d50 = 23.3 mm. Plastic cylinders planted in an irregular pattern in the channel beds were used to model rigid submerged vegetation. The velocity components were recorded by using an ADV at 200 Hz. In this study, the distributions of velocity, Reynolds stress, and TKE were investigated for flows in the presence of submerged rigid vegetation in channel beds with various area densities of vegetation. Results show that the shape of Reynolds stress distribution depends on the entrance and exit slopes of the pool, as well as the irregular distribution pattern of vegetated elements. Inside the pool with the presence of submerged vegetation in the channel bed, the maximum TKE appears above the bed surface with a larger distance depending on the area density of vegetation in the channel bed. However, the momentum exchange and turbulent energy are likely influenced by the secondary circulation of the flows associated with the irregular distribution of vegetated elements in the channel bed. Results of the quadrant analysis show that the momentum between the flow, bedform, and vegetated elements is mostly transferred by sweep and ejection events. The outward event tends to grow toward the water surface, reaching the highest amount near the water surface. At the pool entrance section where the flow is decelerating, the ejection event is dominant near the bed while the sweep event is strong near the water surface. With the decrease in the vegetation density in the pool bed, both the ejection and outward events become dominant.
Новые местонахождения сосудистых растений из Красной книги Магаданской области
Authors:   Institute of Biological Problems of the North, FEB RAS, Magadan, Mochalova O. A. , Khoreva M. G. ,   Institute of Biological Problems of the North, FEB RAS, Magadan, Andriyanova E. A. ,   Institute of Biological Problems of the North, FEB RAS, Magadan
Published: June 2022

New data on the locations of 10 species of vascular plants for the regional Red Data Book have being presented. The findings of very rare in the region Beckwithia chamissonis, Magadania olaёnsis, Rhodiola quadrifida, and Valeriana murrayii are of the greatest interest. The localities of Tofieldia cernua and Lysiella oligantha, missed in the Red Data Book of Magadan Oblast, have been reported.
MenGO: A NOVEL CLOUD-BASED DIGITAL HEALTHCARE PLATFORM FOR ANDROLOGY POWERED BY ARTIFICIAL INTELLIGENCE, DATA SCIENCE & ANALYTICS, BIO- INFORMATICS AND BLOCKCHAIN
Authors:   SystemOnSilicon Corporation, TX,  Stony Brook University, Stony Brook, NY, USA, Ray Rajarshi (Raj) ,   The University of Texas at Austin, TX, USA, Agar Zack ,   SystemOnSilicon Corporation, TX,  Stony Brook University, Stony Brook, NY, USA, Dutta Pratik , Ganguly Streetam ,   SystemOnSilicon Corporation, TX,  Stony Brook University, Stony Brook, NY, USA,   Indian Institute Of Engineering Science and Technology (IIEST), India, Sah Purushottam ,   SystemOnSilicon Corporation, TX,  Stony Brook University, Stony Brook, NY, USA, Roy Debarshi ,   Alcorn State University, Lorman, MS, USA
Published: June 2022

Digital innovation & transformation, a technology revolution triggered by the latest advancements in the IT sector, has redefined several socially significant domains including healthcare, agriculture, food, finance, and education since the turn of this millennium. Although the power of digital technology has played a key role in modernizing many areas of the healthcare arena, a critical sub-category like andrology i.e., sexual and reproductive health of men, is yet to reap the full benefit of digitalization. This paper describes and explains how MenGO, the world’s 1st data science and analytics powered digital healthcare solution for andrology, is ushering in a new era of men’s health, a traditionally neglected domain, with innovative applications of cutting-edge technologies such as artificial intelligence, machine & deep learning, natural language processing, bioinformatics, blockchain, and cloud computing. MenGO offers custom recommendations, contextual guidance, smart alerts, in-depth report analytics, and statistical guidance for physicians, health institutions, biomedical researchers, pharma houses, insurance companies, and common users. The data analytics engine of MenGO helps users with personalized analytics, physicians with predictive and prescriptive analytics, and caregiving institutes with demographic analytics. A one-stop solution for men suffering from chronic ailments like erectile dysfunction, infertility, ejaculation problems, prostate gland issues, etc. MenGO helps users access affordable physiological and psychological treatments through its cloud and big data analytics powered smart and interactive telehealth platform.
Using Case Based Reasoning, in the Student Graduation Prediction System (CBR)
Authors: Rahardja Untung
Published: June 2022

The performance of an educational institution is considered to have a negative impact due to the high percentage of students who do not graduate on time. Therefore, the number of students must be calculated and anticipated, so this paper needs to propose a model for predicting student graduation rates and predicting the time of graduation for each student. The K-Nearest Neighbor (KNN) method and algorithm were developed using Case-Based Reasoning (CBR). The research was conducted with training data taken from data from students who had graduated, and as a trial, the sixth-semester student data was used. The research attributes required to consist of the grade 1 to semester 5 of the achievement index (IPS) and the students' age. Model testing is carried out with four scenarios where the distribution of training data and testing data is also needed as support. The experimental results show that the stability of the data accuracy value on CBS using the KNN algorithm is found in the 90% training data scenario and 10% test data, namely 90.24% with the closest neighbors K = 5, K = 7, and K = 9. It can be concluded that the model. The resulting prediction system can predict whether students will graduate on time or not. This research will be helpful if implemented in higher education performance to increase student achievement to graduate on time.
GRANO DE MAÍZ COMERCIALIZADO EN MÉXICO COMO POTENCIAL DISPERSOR DE EVENTOS TRANSGÉNICOS
Authors: Trejo-Pastor Viridiana , Espinosa-Calderón Alejandro , Mendoza-Castillo Ma. del Carmen , Kato-Yamakake Takeo Á. , Morales-Floriano Maria Luisa , Tadeo-Robledo Margarita , Wegier Ana
Published: June 2022

Conservar la diversidad del maíz sin transgenes será posible cuando se entiendan las fuentes de introgresión y dispersión de estos genes modificados. El objetivo de este estudio fue analizar la presencia de transgenes en granos y semillas de maíz comercializados en México, por considerarse como potenciales dispersores de eventos transgénicos. Se recolectaron 40 muestras de granos y semillas de híbridos comercializados en México en parcelas de producción o comercializados de origen nacional e importado. Se sembraron en campo 300 semillas por genotipo y cuando se encontraban en etapa V4-V5 de desarrollo foliar se les asperjó glifosato, evaluando 15 días después su efecto. Con base en la frecuencia de resistencia (FR) y nivel de daño se seleccionaron genotipos para ser evaluados con inmunoensayos ELISA para detección de la proteína recombinante CP4/EPSPS y una prueba basada en ADN para detección de presencia/ausencia de P35S de CaMV y TNOS de A. tumefaciens por qPCR. Las muestras que resultaron positivas para P35S y TNOS se enviaron al Centro Nacional de Referencia de Organismos Genéticamente Modificados (CNRDOGM) para su validación y detección de eventos específicos, y se estimaron los porcentajes de eventos de secuencias modificadas contenidos en las muestras positivas. Cuatro híbridos mostraron la mayor resistencia a glifosato en campo (FR ≤ 0.26). En los ensayos ELISA y qPCR los granos del híbrido Jabalí y el importado fueron positivos para la introgresión de transgénicos. Se confirmó la presencia de los eventos MON89034, TC1507 y MON810 (< 0.1 % en cada caso) en grano del híbrido Jabalí, así como los eventos MON89034, MON810, MON88017, NK603, TC1507, Bt11, GA21 y MIR162 (26.42, 2.28, 0.16, 18.13, > 10.0, 8.67, 0.78 y 4.78 %, respectivamente) en el grano importado. La presencia de eventos específicos en granos comercializados quedó comprobada como vía potencial de dispersión de transgenes al maíz nativo, resaltando que estos granos nacionales e importados son semillas funcionales, que conservan su capacidad de desarrollo y de expresión de proteínas recombinantes para resistencia a glifosato.
Neotropical Nepticulidae: a Pictorial Monograph Introducing an Electronic Identification Tool
Authors:   Nature Research Centre, Lithuania, Stonis Jonas R. , Remeikis Andrius ,   Vytautas Magnus University, Lithuania, Diškus Arūnas ,   Vytautas Magnus University, Lithuania
Published: June 2022

The publication deals with 229 species of Nepticulidae (or pygmy moths) from the Neotropics (i.e., the Neotropical and Ando-Patagonian regions) and adjacent areas. The species are illustrated with photographs or drawings of adult forewings, the male genitalia and, if available, leaf mines. In addition to the illustrated species review, the monograph announces about the first electronic diagnostic system (a free electronic tool on the internet) designed for the identification of species of Nepticulidae and includes chapters on the global biodiversity inventory, the collecting of adults and larvae of pygmy moths, preparation of micro-mounts of genitalia structures of Nepticulidae, global generic composition of the family, some particularities of Nepticulidae biology, a unique morphology guide based on the forewing pattern and male genitalia, descriptions of four newly named species, and a taxonomic checklist of the species currently known from the Neotropics and adjacent areas.
Avifauna of the Oued Bouhellou Valley (Morocco): remarkable diversity, five new breeding cases and mapping of nesting sites
Authors: Achiban Hamid , Mansouri Ismail , Squalli Wafae , Achiban Hassan , Afenzar Miloud , Taous Ali
Published: June 2022

In this study, we surveyed and documented diversity and nesting of avian species and their foraging and breeding resources along the Oued Bouhellou watershed (North-Eastern Morocco).
A total of 120 field visits were conducted between 2018 and 2022. We recorded 85 avian species of migrants and residents, belonging to 25 families and 8 orders. The families of Accipitridae (12 species) and Muscicapidae (10 species) were the most abundant, while the observed families of Corvidae, Sturnidae, Prunellidae, Caprimulgidae, and Ciconiidae were represented less abundantly, i.e., by one species each. Equally, nests of 17 breeding species were recorded and mapped along the watershed, breeding counts of the globally endangered Egyptian vulture and the globally vulnerable Turtle Dove pairs were done, and the first breeding cases of the Western Bonelli’s Warbler, Woodchat Shrike, Great Grey Shrike, Common Nightingale, Black Kite, and the North African Long-legged Buzzard were confirmed. The nesting sites were distributed along the watershed depending on specific requirements of each species, with nesting sites of passerines separated from those of raptors. The species richness of birds is supported by the availability of both foraging and breeding resources. In summary, in this study, we recorded the avian diversity, mapped the nesting sites of the breeding bird species, and confirmed the first breeding cases for five species, thus significantly contributing to the ornithology of Morocco and the Southern slope of the Mediterranean basin.
Rozwój duchowy dziecka w pedagogice Janusza Korczaka
Authors: Sieradzka-Baziur Bożena
Published: June 2022

CEL NAUKOWY: Celem artykułu jest pokazanie rzadziej podejmowanego w pedagogice zagadnienia, jakim jest rozwój duchowy wychowanka.
PROBLEM I METODY BADAWCZE: Problem podjęty w artykule ma formę dwóch pytań: Jakie sposoby opisywania duchowości i jej wyrażania wykorzystał w swoich tekstach Korczak? Jakie podejmował działania, aby wychować uduchowione dziecko? Metoda przyjęta w pracy to analiza semantyczna wybranych tekstów wielkiego pedagoga, wspomnień jego wychowanków i innych osób, z którymi pozostawał w bliskich relacjach, oraz opracowań naukowych na temat jego życia i twórczości.
PROCES WYWODU: W artykule zostało zaprezentowane zagadnienie opisywania i wyrażania duchowości przez Korczaka w jego tekstach, a także jego działania podejmowane w celu wychowania uduchowionego dziecka.
WYNIKI ANALIZY NAUKOWEJ: Z analizy tekstów Korczaka na temat duchowości i podejmowanych przez niego działań wynika, że jednym z celów, jakie sobie stawiał, było to, aby uczynić swoje życie i życie swoich wychowanków bardziej uduchowionym.
WNIOSKI, INNOWACJE, REKOMENDACJE: Podjęte zagadnienie wymaga dalszych studiów nad językiem religijnym Korczaka oraz przeprowadzenie całościowej analizy semantycznej wszystkich wspomnień wychowanków wielkiego pedagoga.
Aksjologiczne aspekty duchowości młodych Europejczyków
Authors: Rodziewicz Barbara
Published: June 2022

CEL NAUKOWY: Celem artykułu jest odtworzenie utrwalonych w świadomości językowej młodych Europejczyków – Polaków, Rosjan i Niemców sposobów rozumienia wartości chrześcijańskich jako jednego z aspektów duchowości.
 PROBLEM I METODY BADAWCZE: Problem badawczy został sformułowany jako pytania: Czym są dziś wartości chrześcijańskie dla młodych obywateli Europy? Czy dla wyznawców katolicyzmu, prawosławia i protestantyzmu są one tak samo ważne i niosą identyczne treści oraz przesłania? W celu pozyskania danych językowych zastosowano psycholingwistyczne narzędzie badawcze – test swobodnych skojarzeń werbalnych z wyrazami hasłowymi wartości chrześcijańskie, christliche Werte, xристианские ценности. Do analizy materiału empirycznego wykorzystano wypracowaną na gruncie lingwistyki kognitywnej metodę profilowania pojęć, a także metodę analizy frekwencyjnej.
PROCES WYWODU: Wywód rozpoczyna uzasadnienie wyboru problematyki wartości chrześcijańskich oraz ukazanie specyfiki istoty duchowości i jej związków z aksjologią. Następnie przedstawiono metodologię zebrania i analizy danych językowych. Część trzecia to omówienie wyników testu swobodnych skojarzeń werbalnych oraz wnioski.
WYNIKI ANALIZY NAUKOWEJ: Za wartościami chrześcijańskimi kryją się w przekonaniu respondentów przede wszystkim idee zawarte w Dekalogu, w dalszej kolejności ogólnie pojmowana moralność. Symbolizują je krzyż, Biblia i ikona. Transmisja i pielęgnowanie wartości należą do zadań Kościoła. W świadomości językowej respondentów niemieckich i polskich dokonuje się raczej negatywna ewaluacja wartości chrześcijańskich, badani Rosjanie mają do nich stosunek ambiwalentny.
WNIOSKI, INNOWACJE, REKOMENDACJE: Wartości chrześcijańskie są kategorią aksjologiczną silnie utrwaloną w świadomości językowej przedstawicieli trzech zbiorowości etnicznych. Eksploracja pól asocjacyjnych wykazuje, że profile wartości chrześcijańskich różnią się stopniem złożoności, nasycenia i frekwencji oraz ukształtowaniem pod względem językowym, ujawniając jednakże podobieństwo w zakreślonej skojarzeniami rozpiętości semantycznej.
Energy dissipation of para-positronium in polymers and silica glass
Authors: Kobayashi Yoshinori , Sato Kiminori , Yamawaki Masato , Michishio Koji , Oka Toshitaka , Washio Masakazu
Published: June 2022

In this letter we discuss the energy dissipation of short-lived para-positronium (p-Ps) in polymers and silica glass. The S parameter characterizing the Doppler broadening of p-Ps annihilation is determined from the previously reported systematic data of positron annihilation age momentum correlation for various polymers and silica glass. A comparison of the S parameter with that expected for thermalized p-Ps trapped in a free volume reveals that p-Ps is not thermalized and possesses excess energy in fluorinated polymers and silica glass, indicating that it is difficult for Ps to lose energy in substances containing heavy elements such as fluorine and silicon.
BIOLOGICAL FEATURES OF GROUNDNUT MICROSYMBIONTS WIDESPREAD IN THE SOILS OF UKRAINE
Authors: D. V. Krutylo
Published: June 2022

Objective. Study the presence of nodule bacteria in the soils of Ukraine, capable of nodulatinggroundnut, isolate new strains of rhizobia from peanut nodules, study their morphological, culturaland serological properties and the ability to form symbiosis with different legumes. Methods. Microbiological (isolation of nodule bacteria from nodules and cultivation of microorganisms, studying biological properties of strains), serological (producing antisera to Bradyrhizobium lupini367a, studying rhizobia diversity in groundnut nodule populations, studying serological identity ofnew strains), vegetation experiment (studying formation and functioning of groundnut symbioticsystems with nodule bacteria, studying host specificity of new strains of groundnut rhizobia), gaschromatography (determining nitrogen-fixing activity of rhizobia in symbiosis with groundnut),mathematical and statistical. Results. Representatives of two species, B. lupini and B. japonicum,were found in nodule populations of rhizobia during the cultivation of groundnut plants on sodpodzolic soil and leached chernozem. The dominant microsymbionts of groundnut were lupine nodule bacteria of serogroup 367a (54.2 % and 45.8 % according to soils). Fewer nodules wereformed by intensive growing soybean rhizobia of serogroup КВ11 (16.7 % and 12.5 %). The shareof nodule bacteria not classified in the studied serogroups was 21.9 % and 41.7 %. Fifteen newstrains of nodule bacteria were isolated from groundnut nodules, which were morphologically, culturally and serologically identified as B. lupini serogroup 367a (7 of them), B. japonicumserogroup KB11 (4 of them) and Bradyrhizobium sp. (4 of them). New strains of B. lupini fromgroundnut nodules are able to infect white and yellow lupine but do not nodulate soybeans. Strainsidentified as B. japonicum form nodules on soybean roots but do not infect lupine. Serologically unidentified strain Bradyrhizobium sp. AR3, which is able to form a symbiosis with both lupine andsoybean (phenotypes Nod+Fix+) was obtained. Conclusion. For the first time it was established thatgroups of nodule bacteria capable of nodulating groundnut are present in the agrocenoses ofUkraine. Fifteen new strains of groundnut rhizobia were obtained, which were identified as B. lupini, B. japonicum and Bradyrhizobium sp.
Photo-thermal tuning of graphene oxide thin film coated integrated optical waveguides
Authors: Moss David
Published: June 2022

We experimentally investigate power-sensitive photo-thermal tuning (PTT) of two-dimensional (2D) graphene oxide (GO) films coated on integrated optical waveguides. We measure the light power thresholds for reversible and permanent GO reduction in silicon nitride (SiN) waveguides integrated with 1 and 2 layers of GO. Raman spectra at different positions of a hybrid waveguide with permanently reduced GO are characterized, verifying the inhomogeneous GO reduction along the direction of light propagation through the waveguide. The differences between the PTT induced by a continuous-wave laser and a pulsed laser are also compared, confirming that the PTT mainly depend on the average input power. These results reveal interesting features for 2D GO films coated on integrated optical waveguides, which are of fundamental importance for the control and engineering of GO’s properties in hybrid integrated photonic devices. 
Síndrome de burnout em enfermeiros de estratégia saúde da família do sul do Brasil
Authors: Raquel Kist Daiane , Gonçalves Possuelo Lia , Frantz Krug Suzane Beatriz
Published: June 2022

Objetivo: identificar a prevalência da Síndrome de Burnout e as características sociodemográficas e ocupacionais associadas em enfermeiros de ESFs de municípios da 28ª Região de Saúde do Rio Grande do Sul. Método: trata-se de um estudo transversal, incluindo enfermeiros de Estratégia Saúde da Família de 13 municípios de uma região do sul do Brasil que responderam um questionário online com aspectos sociodemográficos e ocupacionais e o Maslach Burnout Inventory para mensurar o desfecho de SB no período de março a agosto de 2018. Resultados: um total de 47 enfermeiros respondeu o instrumento. A prevalência de Síndrome de Burnout foi de 57,4%. Os enfermeiros que possuem interesse em trocar de profissão, assim como aqueles que trabalhavam na zona urbana apresentaram associação com a Síndrome de Burnout (p≤0,05). Conclusão: o estudo demonstrou alta prevalência de Síndrome de Burnout entre os enfermeiros que atuam em ESFs da 28ª Região de Saúde, indicando predisposição em desenvolvê-la.
O papel da enfermagem nas síndromes hipertensivas da gravidez: Revisão integrativa
Authors: De Araújo Damasceno Ana Alice , Augusto Cardoso Marly
Published: June 2022

Objetivo: identificar as evidências disponíveis na literatura sobre o papel da enfermagem na assistência as gestantes com síndromes hipertensivas na gestação. Método: Trata-se de uma revisão integrativa baseada na estratégia PICO, realizada com 13 artigos indexados nas bases de dados LILACS, SciELO, BDENF, MEDLINE. Os critérios de inclusão consideraram artigos disponíveis na íntegra e publicados entre 2009 a junho de 2021. Resultados: Para análise, os estudos foram divididos em 3 categorias: 1. O conhecimento dos profissionais de enfermagem sobre as síndromes hipertensivas na gestação; 2. Os cuidados de enfermagem à gestante com síndromes hipertensivas na gestação e seus neonatos; 3. A sistematização da assistência em enfermagem no cuidado as síndromes hipertensivas na gestação. Conclusão: Os estudos analisados demonstram as interfaces e desafios da enfermagem no cuidado às gestantes com síndromes hipertensivas na gestação, apontando o papel primordial da enfermagem na atenção à saúde da gestante.
HUBUNGAN ANTARA DAYA LEDAK OTOT TUNGKAI DAN PANJANG TUNGKAI TERHADAP HASIL TENDANGAN JARAK JAUH OLAHRAGA SEPAKBOLA
Authors: Yahya Tohari  , Ardian Cahyadi  , Marta Dinata  , Ade Jubaedi  , Dimas Duta Putra Utama  , Satria Armanjaya
Published: June 2022

Penelitian ini bertujuan mengetahui adaya hubungan antara gaya ledak otot tungkai dan panjang tungkai yang diambil dari hasil tendangan jarak jauh pada SSB Porsibu FC Lampung Tengah. Metode dalam penelitian ini adalah deskriptif korelasional. Subjek penelitian siswa binaan SSB Porsibu FC Lampung Tengah berjumlah 30 anak. Analisis data menggunakan korelasi product moment. Instrumen yang digunakan untuk mengukur daya ledak otot tungkai menggunakan standing broad jump, panjang tungkai menggunakan Antropometer, dan tendangan jarak jauh dengan long pass test. Hasil dari penelitian ini, (1) terdapat hubungan yang signifikan antara daya ledak otot tungkai pada tendangan jarak jauh dengan r-hitung 44.087>0,361 r-tabel. (2) terdapat hubungan yang signifikan antara panjang tungkai pada tendangan jarak jauh dengan r-hitung 136.03>0,361 r-tabel. (3) terdapat hubungan yang signifikan antara daya ledak otot tungkai dan panjang tungkai pada tendangan jarak jauh dengan rhitung 3.711>0,361 rtabel. Penelitian ini H3 diterima, maka dapat disimpulkan terdapat hubungan yang signifikan antara daya ledak otot tungkai dan panjang tungkai terhadap hasil tendangan jarak jauh sepakbola.
PELATIHAN MODIFIKASI AGILITY LADDER DRILL 3 REPETISI 5 SET TERHADAP KELINCAHAN SISWA PESERTA EKSTRAKULIKULER PENCAK SILAT
Authors: I Gst Ngr Agung Cahya Prananta  , I Gusti Putu Ngurah Adi Santika
Published: June 2022

Berdasarkan studi pendahuluan yang telah dilakukan, peneliti melakukan observasi terhadap siswa dengan tujuan untuk mengetahui apakah perlu diadakan penelitian lebih lanjut. Terkait dengan hal tersebut, didapatkan hasil bahwa siswa peserta ekstra kurikuler pencak silat SMP Negeri 1 Manggis memerlukan pelatihan untuk meningkatkan kelincahan dalam teknik menghindar dan mengubah arah. Tujuan dari penelitian ini adalah untuk mengetahui dampak yang dihasilkan dari pelatihan modifikasi agility ladder drill 3 repetisi 5 set terhadap kelincahan siswa peserta ekstrakurikuler pencak silat di SMP Negeri 1 Manggis. Sampel dalam penelitian ini berjumlah 20 orang yang diperoleh melalui rumus Pocock yang memenuhi kriteria inklusi. Dalam penelitian ini diperoleh hasil penelitian bahwa pelatihan modifikasi agility ladder drill 3 repetisi 5 set meningkatkan kelincahan tubuh dengan peningkatan 21 detik atau meningkat 12,92%. Pada penelitian ini diperoleh kesimpulan bahwa pelatihan modifikasi agility ladder drill 3 repetisi 5 set terbukti meningkatan kelincahan tubuh siswa Peserta Ekstrakulikuler Pencak Silat SMP Negeri 1 Manggis.
THE ANALYSIS OF THE SECOND KARABAKH WAR FROM THE PERSPECTIVE OF JUST WAR THEORY
Authors:   Khazar University Master, Zaur Ibrahimli Aytaj
Published: June 2022

Açar sözlər: Ədalətli müharibə nəzəriyyəsi, İkinci Qarabağ müharibəsi, Jus ad bellum, Jus in bello Jus post bellum Keywords: Just War Theory, Second Karabakh War, Jus ad bellum, Jus in bello, Jus post bellum The war between Azerbaijan and Armenia, which began on September 27 and lasted for 44 days, was called the Second Karabakh War. How the course and consequences of the war will affect the two countries, as well as the situation in the region, is one of the most important issues at the moment. Another important point is whether the war and its consequences are fair to the parties.
CİNAYƏT PROSESSUAL HÜQUQDA İSTİNTAQ HƏRƏKƏTLƏRİNİN ANLAYIŞI, TƏSNİFAT BÖLGÜSÜ, TƏTBİQ EDİLMƏ ŞƏRTLƏRİ VƏ ƏSASLARININ NƏZƏRİ-TƏCRÜBİ MÜQAYİSƏLİ TƏHLİLİ
Authors:   Gəncə, Azərbaycan, Taleh oğlu Allahverdiyev Ömər
Published: June 2022

Açar sözlər: anlayış, bölgü, qanunvericilik şərtləri, hüquqi, faktiki əsaslar Key words: concept, division, legal terms, legal, factual bases Mövzunun aktuallığı budur ki, istintaq hərəkətlərinin prosessual əsasları ilə bağlı milli prosessual normalarında olan ən böyük çatışmazlıq cinayət prosessual məcəllənin xüsusi hissəsində istifadə olunan termin və anlayışların ümumi hissəsinin 7-ci maddəsində anlayışının verilməməsidir. Bu kimi anlayışlara “istintaq hərəkətləri” də daxildir. Məsələ burasındadır ki, qanunverici istintaq hərəkətlərini təsbit edən fəsilləri elə ardıcıllıqla yerləşdirmişdir ki, təcrübədə də problemlər yaranır. Məsələn, məhkəmə ekspertizasının, tədqiqat üçün nümunələrin götürülməsinin də bu ardıcıllığa daxil edilməsi praktiki çaşqınlıqlar yaradır. Prosessual normalarda istintaq hərəkətlərinin tənzimlənməsinə dair belə ümumi problemlər bütün cinayətlərinin istintaqında özünü büruzə verir. Ona görə də ilk növbədə qanunverici 7-ci maddədə istintaq hərəkətinə anlayış versə, daha düzgün olar. Bu, həmçinin istintaq hərəkətlərini həyata keçirən subyektlərin də dairəsini müəyyənləşdirmiş olacaqdır, çünki qanunverici subyektlərlə bağlı normalarda müstəntiqə səlahiyyət verir ki, müxtəlif istintaq ELMİ ARAŞDIRMALAR / Tezislər toplusu / Cild: 2 Sayı: 02 SCIENTIFIC RESEARCH / Collection of theses / Volume: 2 Issue: 02 DOI: https://www.doi.org/10.36719//2022/02/02 10 hərəkətlərinin aparılmasını təhiqiqat orqanlarına həvalə etsin. Bu isə nəzəri-təcrübi baxımdan yetərincə mübahisələr doğurur. Birmənalı şəkildə iddia edilir ki, istintaqın aparılmasına aparıcı mövqe müstəntiqə aiddir, çünki işin detallarını o bilir. Belə olduğu halda, onun hər hansı bir istintaq hərəkətini aparmağı təhqiqat orqanına tapşırması formallıqdan başqa bir şey olmayacaqdır.
OPPORTUNITIES FOR USING INNOVATIVE POTENTIAL IN THE AGRICULTURAL SECTOR
Authors:   Baku State University doctor of economic sciences, professor, Amarahmad Hasanova Pari
Published: June 2022

The comprehensive development of regions in the modern era is the basis of the economic policy of the Azerbaijani state. Economic measures implemented by the head of state in the agricultural sector have a great impact on the socio-economic development of the country. The agricultural sector is an important part of the primary sector and plays a large role in the development of the country's economy. The modern era is a technological era, and regardless of its diversity, these technologies should be used as efficiently as possible. The studied methods and models play an important role in the production of high-quality and environmentally friendly products in the agricultural sector. For this, the use of modern innovative methods of information technology is of great importance. Key words: technology, innovation, agricultural sector, economic potential, erosion, soil research, innovative potential
AZƏRBAYCAN MİLLİ KOSTYUMLARININ ESTETİKASI
Authors:   Azərbaycan Texnologiya Universiteti texnika üzrə fəlsəfə doktoru, Rüstəm oğlu Əliyev Şakir , Elşən qızı Orucova Müjgan ,   Azərbaycan Texnologiya Universiteti magistrant
Published: June 2022

Key words: costume, aesthetics, style, fashion, image, functionality, originality, skill Açar sözlər: kostyum, estetika, stil, üslub, obraz, funksionallıq, ojinallıq, sənətkarlıq Geyimlər hələ ibtidai dövrlərdən insanların bədənini ətraf təsirlərdən qorumaq, bədənin istiyə ehtiyacını ödəmək xarakteri ilə yaranmışdır. Lakin zaman keçdikcə özünün tələbləri ilə geyimləri də dövrün inkişafına uyğun formalaşdırırdı. Hər bir xalq öz ənənəsinə, dünyagörüşünə, inanclarına məxsus geyim mədəniyyətini yaratdı. Aparılan ticarət nəticəsində daha da təkmilləşdirildi. Geyimin tarixi ilə məşğul olan insanların əksəriyyəti, etik normalara əməl edilməsi və insanların zaman – zaman inkişaf edən estetik zövqlərinin təmin edilməsi zərurətini də geyim elementlərinin meydana gəlməsində müqəddəs şərtlər hesab edirlər.
XIX ƏSRDƏ AZƏRBAYCAN QADINININ İCTİMAİ HƏYATDA MÖVQEYİNƏ DAİR
Authors:   AMEA Milli Azərbaycan Tarixi Muzeyi tarix üzrə fəlsəfə doktoru, dosent, Mirzəli oğlu Şiriyev Tural
Published: June 2022

Açar sözlər: Azərbaycan qadını, ictimai məişət, ənənə, ictimai münasibətlər, qadın hüququ Key words: Azerbaijani women, public life, tradition, public relations, women's rights Tarixi ədəbiyyat və etnoqrafik materialların elmi təhlili göstərir ki, Azərbaycanda tarixən ənənəvi ictimai məişət münasibətləri milli dəyərlər, islam dininin mənəvi bazası əsasında formalaşıb, inkişaf etmişdir. XIX əsrdə Azərbaycanda patriarxal münasibətlər hakim idi. Hələ ibtidai icma dövründə istehsalın tərəqqisi, əkinçilik və maldarlığın inkişafı cəmiyyət həyatında böyük təbəddülatlara səbəb olmuş, təsərrüfatda və ictimai həyatda kişilərin rolu artmışdır. Nəticədə, anaxaqanlığından ata nəslinə – patriarxala keçid baş vermiş, nəsilə mənsubiyyət ata xətti ilə müəyyən edilməyə başlanmışdır (Engels, 1953: 33). Başqa sözlə, “qan qohumluğuna mənsub adamları əhatə edən qəbiləni ailə icması, yaxud böyük patriarxal ailə əvəz etmişdir” (Quliyev, 1986: 88). Göründüyü kimi, ictimai-iqtisadi təkamül prosesi təməl prinsip kimi tamamilə təbii amillərdən asılı olaraq, cəmiyyətdə kişi ilə qadının hüquq və vəzifələrini müəyyən etmişdir.