bluuebunny/crossref_metadata_2025 huggingface dataset:
HUBUNGAN KEBERSIHAN PERSONAL DENGAN INFEKSI CACING Soil Transmitted Helminth (STH) PADA FESES ANAK SDN 1 KEDAMEAN KABUPATEN GRESIK
Authors: Farida Elis Anita , Salim Siti Zainab , Charisma Acivrida Mega , Wahyuni Khurin In
Published: January 2020

Infeksi cacing merupakan penyakit endemik kronik yang di akibatkan satu atau lebih cacing yang masuk kedalam tubuh manusia, dengan prevalensi tinggi terdapat pada anak-anak. Infeksi cacing yang menjadi masalah utama adalah kelompok Soil Transmitted Helminths (STH) diantaranya Ascaris lumbricoides, Trichuris trichiura, Necator americanus dan Ancylostoma duodenale. Penelitian ini bertujuan untuk mengetahui apakah siswa SDN 1 Kedamean terinfeksi telur cacing Soil Transmitted Helminth (STH) dan untuk mengetahui adanya hubungan personal kebersihan dengan prevalensi kecacingan pada feses anak SDN 1 Kedamean. Penelitian ini menggunakan teknik Random Sampling yaitu semua siswa kelas 3 SD sampai kelas 5 SD yang memenuhi kriteria inklusi dan eksklusi. Banyaknya sampel penelitian ini adalah 30 sampel yang diambil dari kelas 3, 4, dan 5 dan dianalisis menggunakan Statistika  fisher exact. Pada penelitian ini diperoleh 5 siswa yang terinfeksi telur cacing Soil Transmitted Helminth (STH) yang ditemukan yaitu telur cacing Ascaris lumbricoides, Trichuris trichiura, dan Hookworm. Yang terinfeksi Soil Transmitted Helminth (STH) lebih banyak menginfeksi laki-laki (10%) sedangkan pada anak perempuan (6,7%). Dari hasil penelitian disimpulkan bahwa tidak terdapat hubungan antara infeksi cacing dengan kebersihan personal siswa SDN 1 Kedamean.
El hexagrama, entre el centro y la periferia crónica estesiográfica
Authors: Valencia Juan Esteban
Published: January 2020

Este texto es una crónica que cuenta la experiencia del montaje final del PPI (Proyecto Pedagógico Integrador) Hexahedron 2015, de la Escuela Superior Tecnológica de Artes Débora Arango. Para la elaboración del mismo utilicé el concepto de estesis elaborado por Katia Mandoki (2006). Dicha experiencia se llevó a cabo los días 16 y 17 de junio de ese año.

doi:10.17632/bh9226bxnk.1
“AS COISAS DO CÉU”: ETNOASTRONOMIA DE UMA COMUNIDADE INDÍGENA COMO SUBSÍDIO PARA A PROPOSTA DE UM MATERIAL PARADIDÁTICO
Authors: Garcia Caroline Da Silva , Costa Samuel , Pascolai Suzy , Campos Mateus Zanette
Published: January 2020

O objetivo desse trabalho foi identificar o conhecimento etnoastronômico de uma comunidade indígena do norte do Rio Grande do Sul, como subsídio para a produção de um material paradidático a ser utilizado na escola local. Foram utilizadas três etapas para a realização da pesquisa: oficina pedagógica, levantamento do conhecimento de etnoastronomia e confecção do livreto paradidático. A oficina pedagógica tornou público o conhecimento tradicional indígena sobre a criação do Sol e da Lua, o levantamento mostrou saberes tradicionais de astronomia consideráveis, em torno de temas como a criação do Sol e da Lua, as fases da Lua, as estações do ano e as estrelas, e o material paradidático produzido se configurou como o início de um processo de revivificação dos conhecimentos locais entre os membros da comunidade. O processo vivenciado se constituiu em uma etapa inicial de um trabalho que deve ser estimulado, dando continuidade à elucidação da etnoastronomia dos índios da aldeia Guarani MBYÁ Nhu Porá.
USO DE TEXTOS HISTÓRICOS PARA UMA ABORDAGEM PEDAGÓGICA SOBRE A NATUREZA DA CIÊNCIA
Authors: Carvalho Hermano Ribeiro de , Nascimento Lucas Albuquerque do , Silva Boniek Venceslau da Cruz
Published: January 2020

Este trabalho apresenta uma experiência de elaboração, aplicação e análise de Textos Históricos de Natureza Pedagógica envolvendo a recepção, aceitação e disseminação da obra de Nicolau Copérnico. Os textos históricos de natureza pedagógica foram utilizados em um curso de extensão que ocorreu na Universidade Federal do Piauí (UFPI) que contou com a participação de futuros professores de ciências no ensino fundamental, graduandos em Química, Biologia e Ciências da Natureza. Os professores em formação leram os textos e responderam questões referentes aos mesmos, as quais relacionavam aspectos da Natureza da Ciência e da História da Astronomia. Essa ferramenta didática foi utilizada de maneira explícita e reflexiva, com o objetivo de contextualizar os fatos, e subsidiar discussões acerca de aspectos relacionados à Natureza da Ciência. Dessa forma, este trabalho buscou avaliar a legitimidade do uso de textos históricos com finalidade pedagógica para uma melhor inserção da Natureza da Ciência.
MEDICIÓN DE DISTANCIA A LA LUNA CON TELESCOPIO Y CÁMARA DIGITAL EN UNA NOCHE
Authors: Olivieri Néstor A. , Rodríguez Eduardo E.
Published: January 2020

Na introdução do conceito de medida em cursos de física e astronomia básicos, as medidas astronômicas costumam reduzir-se a exemplos de ordem de magnitude. Por outro lado, são habituais abordagens descritivas que não colocam os alunos em contato com instrumentos ou com os objetos de estudo. Pelo contrário, este trabalho mostra como pode ser usado um telescópio amador e uma câmera digital padrão para obter imagens da Lua, e a partir delas calcular a distância ao satélite. A técnica baseia-se em uma simples análise da correlação entre duas imagens captadas desde um mesmo local com intervalo de algumas horas. A pequena variação do tamanho angular da Lua devida ao fato de que a distância Lua-observador varia com a rotação da Terra pode-se pôr em evidência e serve para obter os dados básicos para deduzir a distância ao satélite.
Anatomy of A Murder
Authors: O'Sullivan Shane
Published: January 2020

Shane O’Sullivan’s Anatomy of a Murder – Sirhan Sirhan and Robert Kennedy is a video essay that combines archival material, interview, witness statements and parole hearing recordings relating to the case of Sirhan Sirhan, the person found guilty of assassinating Senator Robert Kennedy in 1968, intercut with footage from trials in well-known Hollywood films. It is a controversial video and, as such, has elicited divergent peer reviews, particularly with regard to its ambiguous position both as an academic research film and polemical campaign video. We therefore publish this partly because of its strengths but also to highlight problems and questions it might raise relating to the place of polemical campaign videos in the context of academic filmmaking – as a contribution to the ongoing dialogue about what constitutes screen media practice research
Isolation of glia from mice
Authors: DEROUICHE Sandra
Published: January 2020

Glia constitutes a heterogeneous cell population that makes up half of the cells in the central nervous system (CNS). Glial cells include macroglia, astrocytes and oligodendrocytes, and microglia. Their roles are very diverse but overall they orchestrate CNS formation and function by providing neurons with essential support. Although glia-derived immortalized cell lines are now available, primary cultures of glial cells still constitute the most reliable method to study glial functions as the primary cultures retain important characteristics and markers of glia from their normal brain environment. Isolation and culturing of glia from postnatal rodent brain is well-characterized and give higher yield than from adult brain. Therefore, isolation of glial cells from postnatal mouse brains, with an emphasis on microglia, will be described. It will include a protocol describing the steps of isolation and necessary equipments and reagents, as well as the subsequent cell culture monitoring and potential applications.
Voltage gated sodium channels and epilepsy
Authors: HEBEISEN Simon
Published: January 2020

Epilepsy is the fourth most common neurological disorder and affects people of all ages. Medication for epilepsy is often life-long and has a major impact on the quality of life - mostly being related to substantial adverse effects. Therefore, over 30% of people with epilepsy do not achieve sufficient seizure control whilst effective medication being available.  Ion channels are often primary targets of anticonvulsant drugs. They can either act as blockers for voltage gated sodium and calcium channels or as activators for potassium or chloride channels. Additionally, modulators of ligand gated ion channels (GABA or Glutamate receptors) are frequently used to treat epilepsy.  Employing a panel of functional electrophysiological assays using fluorescence based methods and patch-clamping on a broad range of voltage and ligand gated ion channels, we were able to successfully screen for drugs with a beneficial action profile. In successful leads we found drugs that selectively interacted with TTX sensitive, neuronal voltage gated sodium channels. Activation and fast inactivation were unchanged, while an increased affinity in the slow inactivated state was observed. This profile is in contrast to traditional anticonvulsant drugs which show their major effects on the fast inactivated state of voltage gated sodium channels. One drug showed substantial shifts of the voltage dependence of the slow inactivation only for NaV1.2 and 1.6. This favours this drug for treating patients with diseases with compromised NaV1.1 function in interneurons, such as Alzheimer's disease.
The effects of quercetin on antioxidant and cytokine levels in rat hippocampus exposed to acute cadmium toxicity
Authors: KISADERE İhsan , DÖNMEZ Nurcan , DÖNMEZ Hasan Hüseyin
Published: January 2020

 The aim of this study was to determine cadmium neurotoxicity (Branca et al.  2018) and beneficial effect of quercetin (QE) (Kanter et al.  2016) against on neuronal damage in hippocampus exposed with acute cadmium (Cd). Adult male Wistar-Albino rats (n = 30) were used and divided into four groups as Control (C, n = 6), Cadmium (Cd, n = 8), Quercetin (Q, n = 8) and Cadmium + Quercetin (Cd + Q, n = 8). Cadmium (CdCl2, 4 mg kg-1 daily, s.c) were administrated to Cd and Cd+Q groups, and Quercetin (Q, 50 mg kg-1 daily, i.p) were administrated to Q and Cd + Q groups for 3 days, respectively. At 4th day after the treatments, hippocampal samples were taken from the four groups. Cadmium decreased superoxide dismutase (SOD) and reduced glutathione (GSH) levels and the SOD activity and GSH level were markedly (p< 0.05) lower in Cd group than in the Q and C groups. Lipid peroxidation (MDA) levels were higher in Cd group when compared to the control, Q and Cd+Q groups. IL1 levels were found statistically higher in Cd group than in the control, Q and Cd+Q groups. IL-6 and TNF-alfa levels were significantly (p< 0.05) higher in Cd and Cd+Q groups than the Q and C groups.  In addition, IL10 levels were detected the lowest in Cd group when compared to other groups.      In conclusion, our results show that quercetin can be beneficial against to neurotoxic effects of acute cadmium toxicity in the rat hippocampus through upregulation of antioxidant system but down regulation of cytokine levels. 
Interactions between chemotherapy-induced neuropathic pain and TRPV1 channel
Authors: OSMANLIOĞLU Haci Ömer
Published: January 2020

As a complex problem, pain activates several conditions, symptoms, and molecular pathways. After stimulation of a nociceptors, action potentials are generated and then propagated to the brain, resulting in a sensation of pain is induces through production and propagation of action potential. Most efficient way to treat chronic pain is with opioids, however the drugs of opioid system induce several adverse effects such as addictive behavior and desensitization. Chemotherapeutic agent (such as oxaliplatin, cisplatin, paclitaxel)-based anticancer drugs cause neurotoxicity through excessive calcium ion (Ca2+) influx. Peripheral neuropathies are a common side effect of treatment of various chemotherapeutics. Today, targeting the cation channels and excessive Ca2+ influx that contribute to the detection of stimuli may be an effective approach in treating chemotherapeutic agents-induced pain syndromes. Several physiological and pathophysiological functions are induced by excessive Ca2+ influx. The Ca2+ passes the cell membrane through several channels such as voltage gated calcium channels (VGCC) and chemical (ligand) channels. In addition to the well-known VGCC and ligand channel, new channels namely transient receptor potential (TRP) channels were discovered within last decades. The TRP superfamily is including 28 members in mammalian and a member of the TRP superfamily is TRP vanilloid 1 (TRPV1) channels. The TRPV1 channel is activated by several stimuli including hot chili pepper component (capsaicin), heat, acidic pH and oxidative stress (Caterina et al. 1997). Expression levels of TRPV1 channel is high in dorsal root ganglion (DRG) and it is mainly responsible from neuropathic pain (Nazıroğlu and Braidy, 2017; Muller et al.  2019). Therefore, TRPV1 channel has great importance in the chemotherapy-induced neuropathic pain induction. In the current study, I will summarize present reports on the TRPV1 channel in literature. as novel target for treating chemotherapy-induced peripheral pain. In addition, I will summarize future directions of the novel targets.
The anticonvulsant effects of salmon calcitonin on pentylenetetrazole-kindled rats
Authors: TAŞKIRAN Ahmet Şevki , ÖZDEMİR Ercan
Published: January 2020

Epilepsy is a disorder of the brain, characterized by an enduring predisposition for the generation of epileptic seizures because of hyperexcitability and hypersynchrony of cortical neurons (Devinsky et al. 2014). Salmon calcitonin is a type of calcitonin with 32 amino acids. It is more potency than human calcitonin due to differences in its amino acid sequence (Masi et al. 2007). In the current study, we investigated the effects of salmon calcitonin on pentylenetetrazoleinduced seizures in kindled rats. In our study, 48 (240-260 g) male Wistar Albino rats were used. Rats were kindled by injections of a subconvulsant dose of pentylenetetrazole (35 mg/kg) once every other day for 15 times. Epileptic behaviors were observed for a period of 30 min. Seizure activity was scored, using the revised Racine’s scale. Rats that had seizure stages of 4 or 5 after three consecutive injections of PTZ were defined as fully kindled.  The kindled rats were divided into six groups (n=8 for each group) as saline (1 ml/kg saline), salmon calcitonin (25, 50 and 100 µg/kg), ethosuximide (100 mg/kg) and ethosuximide + salmon calcitonin. Electrodes were placed to animals’ skulls under stereotaxy to receive electroencephalography (EEG). After thirty minutes of administration of drugs, 35 mg/kg PTZ was given to induce seizures. EEG and video recordings of animals were taken simultaneously for thirty minutes. In the evaluation of the video and EEG recordings, the seizure stages of animals, the first myoclonic jerk time and the number of epileptic seizure spikes were calculated. Salmon calcitonin reduced seizures stage, epileptic seizure spikes and also prolonged first myoclonic jerk time compared to saline group. In addition, salmon calcitonin and ethosuximide combination decreased epileptic seizure spikes and increased the first myoclonic jerk time compare to ethosuximide group. In conclusion, salmon calcitonin decreased epileptic seizures and improved anticonvulsant effect of ethosuximide in the pentylentetrazole-kindled rat. 
Calcium imaging techniques in cell lines
Authors: PECZE Laszlo
Published: January 2020

Calcium imaging is a scientific technique which is designed to measure the intracellular free calcium concentration (Ca2+) in an isolated cell or tissue. Calcium imaging techniques utilizes fluorescent molecules so called Ca2+ indicators that can respond to the binding of Ca2+ ions by changing  heir fluorescence properties. Binding of a Ca2+ ion to a fluorescent indicator molecule leads to either an elevation in its fluorescence intensity or emission/excitation wavelength shift. Two main classes of calcium indicators are chemical indicators and genetically encoded calcium indicators. Chemical indicators are small molecules that can bind calcium ions. This group of indicators includes Fura-2, Fluo-3, Fluo-4, Rhod-2. These dyes are often used with acetoxymethyl esters, in order to render the molecule lipophilic and to allow easy entrance into the cell. Genetically encoded indicators do not need to be loaded onto cells, instead the genes encoding for these proteins can be easily transfected to cells. These indicators are fluorescent proteins derived from green fluorescent protein (GFP). The time-scan mode of laser confocal microscopy is often used for calcium imaging. Intracellular Ca2+ ions generate versatile  intracellular signals that control key functions in all types of cells. In sensory neurons Ca2+ signals are associated with pain transmission.
Voltage gated sodium channels and epilepsy
Authors: HEBEISEN Simon
Published: January 2020

Epilepsy is the fourth most common neurological disorder and affects people of all ages. Medication for epilepsy is often life-long and has a major impact on the quality of life - mostly being related to substantial adverse effects. Therefore, over 30% of people with epilepsy do not achieve sufficient seizure control whilst effective medication being available. Ion channels are often primary targets of anticonvulsant drugs. They can either act as blockers for voltage gated sodium and calcium channels or as activators for potassium or chloride channels. Additionally, modulators of ligand gated ion channels (GABA or Glutamate receptors) are frequently used to treat epilepsy. Employing a panel of functional electrophysiological assays using fluorescence based methods and patch-clamping on a broad range of voltage and ligand gated ion channels, we were able to successfully screen for drugs with a beneficial action profile. In successful leads we found drugs that selectively interacted with TTX sensitive, neuronal voltage gated sodium channels. Activation and fast inactivation were unchanged, while an increased affinity in the slow inactivated state was observed. This profile is in contrast to traditional anticonvulsant drugs which show their major effects on the fast inactivated state of voltage gated sodium channels. One drug showed substantial shifts of the voltage dependence of the slow inactivation only for NaV1.2 and 1.6. This favours this drug for treating patients with diseases with compromised NaV1.1 function in interneurons, such as Alzheimer's disease.
Depression models in experimental animals
Authors: DEMİRDAŞ Arif
Published: January 2020

Depression is a mental disorder that is estimated by the World Health Organization to affect 350 million people worldwide. But its pathogenesis and underlying mechanisms have not been understood yet. To present a satisfying explanation for the causes and treatments of these sorts of diseases animal models can be a powerful model for the researchers. Experimental animal research has been frequently used, in related with clinical studies, to test a number of hypotheses regarding the etiology of depression and its related behaviors. In the literature, experimental animal models about depression were described. These are chronic mild stress, forced swimming test, learned helplessness, tail suspension test, psycho-stimulant drug withdrawal and olfactory bulbectomy. In the oral presentation, it was summarized the experimental animal models that are used most commonly for depression, and discussed their advantages and limitations. In conclusion, it seems that some experimental animal models such as chronic mild stress and forced swimming test in several experiments have been using for investigating depression etiology and treatment and the models are very useful for searching the disease.
Effects of cell phone (900 and 1800 MHz) and Wi-Fi (2450 MHz) frequencies on oxidative stress in laryngeal mucosa
Authors: KÜTÜK Sinem Gökçe
Published: January 2020

The trachea has a composite structure with individual and incomplete cartilaginous rings. Deformation of trachea through surgical process and mechanical applications induces injury of laryngotracheal mucosa (Hussain et al. 2015). Results of recent studies studying the oxidative related values in larynx cancer indicated the importance of oxidative stress. Main reactive oxygen species (ROS) are superoxide radical, hydroxyl radical and singlet oxygen. Production normal level of ROS is a physiological process, because the ROS has been using for physiological functions such as killing bacteria and viruses in the body. The excessive production of ROS is scavenged by enzymatic and non-enzymatic antioxidants. 900 and 1800 MHz frequencies are used in cell phones in several countries including Turkey, although 2450 MHz has been using as Wi-Fi frequency in the countries. The non-ionize cell phone and Wi-Fi frequencies induce their hazardous effects in cells including laryngeal mucosa by excessive production of ROS. Results of recent papers indicated that the antioxidant levels such as glutathione and glutathione peroxidase were decreased in the laryngeal mucosa of animals by the cell phone and Wi-Fi exposures, but oxidative stress levels were increased by the exposures (Aynalı et al. 2013). In the oral presentation, I will summarize the results of recent papers on oxidative stress and antioxidants in neurons and cells including laryngeal mucosa. In conclusion, exposure to the frequencies is accompanied by increased oxidative stress, suggesting that oxidative stress is a cause of electromagnetic radiation-induced laryngotracheal pathophysiology. For clarifying the subject, future studies need on the Wi-Fi and mobile phone frequencies-induced oxidative stress in larynx of animal and human
Dysbiosis of gut microbiota and Alzheimer’s Disease
Authors: AKPINAR Orhan
Published: January 2020

Alzheimer's Disease (AD) is a degenerative, chronic, progressive disease of CNS. Pathological changes that develop in the course of the disease lead to memory loss, alteration of thought, and deterioration of other brain functions. The disease progresses slowly, resulting in cell death and brain damage (Jiang 2017; Knopman 2016). Increased permeability of the intestinal and blood brain barrier due to microbial dysbosis plays a role in the pathogenesis of AD and other neurodegenerative disorders associated with aging. In addition, intestinal microbiota bacterial populations secrete amyloids and lipopolysaccharides in large quantities, which may contribute to the modulation of signaling pathways and the production of proinflammatory cytokines associated with the pathogenesis of AD (Jiang 2017). Amyloid precursor protein (APP) , which constitutes Aβ plaques and is normally secreted by intestinal bacteria, is expressed by the enteric nervous system. However, the accumulation corrupts the CNS functions. Escherichia Coli and Salmonella Enterica are some of the many bacterial strains that express and secrete APP and play a role in the pathogenesis of AD (Tse 2017). Production and clearance of Aβ in CNS is a dynamic change and some bacteria and fungi are amyloid secretions, which disrupt the dynamic balance of Aβ protein in CNS and increase the amyloid levels. This causes Aβ protein accumulation in the brain and a high risk of AD (Hill 2015).It is very important for cognitive function in serotonin, 95% of serotonin is synthesized in intestines and intestinal microorganisms play an important role in the synthesis of serotonin. There is evidence that serotonin may reduce the formation of Aβ plaques and thus reduce AD risk (Hill 2015; Jiang 2017).
Human gut microbiota and Parkinson Disease
Authors: GÜZEL Mustafa
Published: January 2020

Human gut microbiota (GM) has now been accepted as a potential modulator ofhuman biology. Although new to the world of science, GM's impaction brain and behavior has drawn great attention around the globe. Studies have now proven that GM can directly or indirectly modify brain neurochemistry via various mechanisms like neural, immune and endocrine. The intestinal microbiota influence neurodevelopment, modulate behavior, and contribute to neurological disorders. This presentation is an overview of recent findings regarding the GM -brain axis in PD (Braniste et al. 2014; Sampson et al. 2016) Parkinson disease (PD) is the second-most common neurodegenerative disorder. PD patients show alpha-synuclein deposits and neurodegeneration in the enteric nervous system as well as breakdown of the mucosal barrier, bacterial invasion, and mucosal inflammation in the colon. Alterations in GM and increased gut permeability may influence PD pathophysiology via epigenetic processes that alter αSyn regulation (Matsumoto et al. 2010). Sampson et al. (2016) suggest that GM are required for the hallmark motor and GI dysfunction in a mouse model of PD, via postnatal gut-brain signaling by microbial molecules that impact neuroinflammation and αSyn aggregation. They propose that GM regulate movement disorders and suggest that alterations in thehuman microbiome represent a risk factor for PD. GM do not only affect gut physiology, but there is also an intense bidirectional interaction with the brain influencing neuronal activity, behavior, as well as levels of neurotransmitter receptors, neurotrophic factors, and inflammation. Recently, gut microbiome alterations in PD subjects and a connection between GM and motoras well as non-motor symptoms have been described (Sampson et al. 2016; Parashar and Udayabanu 2017)
Experimental Parkinson’s disease models
Authors: IPEK Eda Duygu
Published: January 2020

Parkinson's disease (PD) is a neurodegenerative disease that develops slowly; however, there is no efficient method of early diagnosis, nor is there a cure. It is characterized by the relatively selective loss of dopaminergic neuronal cells in the substantia nigra pars compacta and the presence of alpha-synuclein aggregation named as Lewy bodies and Lewy neurites in surviving affected neurons. Nigrostriatal dopaminergic neurodegeneration is shared with other parkinsonian disorders, including some genetic forms of parkinsonism, but many of these disorders do not have Lewy bodies. An ideal animal model for PD, therefore, should exhibit age-dependent and progressive dopaminergic neurodegeneration, motor and non-motor dysfunction, and abnormal alpha-synuclein pathology. A wide range of neurotoxic agents are used to induce PD, alterations that are similar with dose observed in human PD. These agents are classified mainly by administration route and the species involved. The toxins that are mainly used in present 6- hydroxydopamine, 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine, rotenone, paraquat, reserpine, methamphetamine, 3-nitrotyrosine and isoquinoline derivatives (Tieu, 2011; McDowell and Chesselet, 2012; Bezard et al. 2013). In addition, viral mediated expression of human α-synuclein, as well as the inoculation of pathogenic α-synuclein species from Lewy bodies of PD patients, for accurately modelling progressive self-propagating neurodegeneration and genetic LRRK2 models (PARK8 gene mutation) has been used (Jiang and Dickson, 2018). In conclusion, these models are only approximations, each possibly holding a certain degree of relevance. Thus, researchers should select models whose characteristics are most suitable for addressing the experimental question.
Small-Scale Cultural Tourism Events: Residents' Perceptions on Their Quality and Impacts
Authors: Doumi Maria , Kyriakaki Anna , Stavrinoudis Theodoros
Published: January 2020

In the present article researchers feature the examination of the opinions and attitudes of the residents of Chios island in Greece. It is based on the investigation of both the characteristics (quality, potential, organization) of the island's main annual cultural events (Rocket War,
Agas, and Mostra) and their possible impact on the local society, economy, tourism, and natural environment. Cluster analysis was used to classify the residents under three groups: Embracers, Realists, Neutrals. Each group has particular characteristics and a clearly defined opinion about
local cultural tourism events and their impact on a local level. According to the main findings of the primary research some particularly interesting aspects of the effects of local cultural tourism events both on the local level and on the island's tourism development emerge. The conclusions
drawn from the elaboration of such findings afford an opportunity to understand better the general impact of cultural events and by the same token to assist government bodies, residents, and other stakeholders in maximizing benefits, whenever possible.
The Impacts of Oil Price Shocks on Tourism Receipts for Selected Middle East and North Africa (MENA) Countries: Do Structural Breaks Matter?
Authors: Kisswani Khalid M. , Kisswani Amjad M. , Harraf Arezou
Published: January 2020

One of the short comings in the tourism literature is that research on the oil price–tourism receipts nexus is limited. However, the available studies, to the best of our knowledge, provide limited evidence on the negative effect of oil prices on tourism receipts. Nevertheless,
the related literature did not consider the structural breaks in the analysis, which has proven to be important in the empirical work. As such, in this article we study the oil price–tourism receipts nexus for selected MENA countries in the presence of structural breaks. This is done
by adopting the autoregressive distributed lag (ARDL) bounds test and incorporating the structural breaks. The findings show that the bounds test provides evidence of a long-run relationship between tourism receipts and oil prices after integrating structural breaks into the ARDL model for
most countries.
Happy Memories: Improved Subjective Happiness Through Vacation Recollection
Authors: Kawakubo Atsushi , Oguchi Takashi
Published: January 2020

This study aims to examine the influences of travel during a summer vacation on subsequent subjective happiness. We also investigate the roles of memories of the vacation and of recollecting these memories. The participants reported their degree of subjective happiness via two online
surveys. The analyses showed that the recollection of travel had a positive influence on subsequent subjective happiness. Notably, this effect was not direct but rather mediated through satisfaction with the vacation. The results showed that not only having a fun vacation but also recalling
the memories of that time have the possibility to promote vacationers' well-being. The article concludes with important implications for the success of tourism businesses as well as the enhancement of tourists' senses of well-being. Also the study's limitations provide some interesting avenues
for future research.
Comorbid of Obsessive Compulsive Disorder and Schizophrenia: A Case Report
Authors: Pratiti Budi , Wulandari Patricia , Hidayat Rachmat
Published: January 2020

Abstract

Introduction

                Schizophrenia was a chronic mental disorder that marked by abnormal social and impairment in reality testing ability. A person diagnosed with schizophrenia may experience amount of symptoms including hallucinations, delusions, and disorganized thinking, bizzare speech and behaviour. Obsessive compulsive disorder are well known as a comorbid of schizophrenia. Comorbid OCD will affect treatment of schizophrenia and others mental disorder.

Case Presentation

A 14-year-old student Muslim boy from a rural household in Central Java, Indonesia who had 8 years of formal education and live with his parent was brought to emergency department of mental hospital by his parents who reported a one year history of excessive washing of his body, soaking his body for hours in bathtub and sleep in bathroom. The patient first fell in January 2019; over a six-month period he became progressively deteriorated, lost interest in his hobby, stopped going to school and reduced his food intake. After one week treatment of venlafaxine and risperidone, He became more cooperative and interactive to the examiner. At that time, the patient reported delusional beliefs about contamination, paranoid delusion and there were several indications of formal thought disorder, including derailment, neologisms, concrete thinking, circumstantiality, and illogicality. An intelligence test revealed average intelligence (IQ=100). The total score of the Brief Psychiatric Rating Scale (BPRS) 3 dropped from 42 to 24, the score on the Yates-Brown Obsessive Compulsive Symptoms (YBOCS)4 scale dropped from 24 to 18, and the score on the Global Assessment of Functioning scale (GAF)5 increased from 25 to 55. After discharge the patient adhered to his medication regimen and at three months after discharge his clinical improvement persisted; he was able to maintain is his personal hygiene and take care of his daily needs, but he remained socially isolated and was unable to return to school.

 

Conclusion

Obsessive compulsive disorder and schizophrenia could happen together in one individual. The treatment should consider underlying condition and cognitive function, especially if patient in productive age.
Formation of conceptual model of transfer policy in social sphere of Ukraine
Authors: Emelianenko Larysa , Moskvina Valeriia
Published: January 2020

Purpose. The aim of the article is investigation of the principles of transfer policy functioning with further development of conceptual model of transfer policy in the social sphere.

Methodology of research. A comparison method is used in the study to identify and formulate concepts of transfer and transfer policy; method of critical analysis - to outline the framework of legislative regulation of transfer policy in Ukrainian practice; method of analogy - to reveal the specifics of the operation of transfer policy not only for budgetary relations, but also for the social sphere.

Findings. The conceptual model of transfer policy functioning is considered. National peculiarities of policy implementation in foreign practice and problems of implementation of transfers in the social sphere into the national economy are investigated. The definition of transfer policy for both the national level and the local government level is given.

Originality. The results of the study will have a high level of significance, because, according to the experience of other countries, the use of transfer policies in the social sphere can reduce poverty in the country and reduce budgetary burden. Thus, a conceptual model of transfer policy is formed in the article based on the implementation of world experience. The efficiency of the transition to transfers in social policy is proved; the mechanism of the administration of transfers is highlighted. Further development has been the use of world-wide experience of the transfer mechanism as a tool for social policy implementation by the government, with the aim of simultaneously reducing poverty and reducing the tax burden, as well as using the experience of implementing transfers from other countries.

Practical value. The results of the study can serve as a starting point for the development of social programs, the creation of an effective social budget in Ukraine both at the national level and at the local level of distribution of financial resources.

Key words: transfer; model; budget; social sphere.
Faktor Yang Berhubungan dengan Kejadian Keberhasilan Induksi Persalinan di Rumah Sakit Umum Bahagia Makassar Tahun 2019
Authors: Aspar Hukmiyah , Harun Ayatullah , Sukarsih Sukarsih
Published: January 2020

Berdasarkan survey penelitian yang dilakukan oleh peneliti di Rumah Sakit Umum Bahagia Makassar, pada tahun 2016  jumlah ibu bersalin sebanyak 873 orang dan yang mengalami induksi persalinan sebanyak 91 orang, data pada tahun 2017 jumlah ibu bersalin sebanyak 301 orang dan yang mengalami induksi persalinan 69 orang. Sedangkan pada tahun 2018 jumlah ibu bersalin sebanyak 915 orang dan yang mengalami induksi sebayak 54 orang, dan pada tahun 2019 periode januari sampai dengan april sebanyak 337 ibu bersalin dan jumlah ibu yang diinduksi sebanyak 39 orang (Data Rumah Sakit Umum Bahagia Tahun 2019).Tujuan dilakukan penelitian ini adalah untuk mengetahui Bagaimana hubungan antara Usia kehamilan, Ketuban Pecah Dini, Inersia Uteri, dengan kejadian keberhasilan induksi persalinan di Rumah Sakit Umum Bahagia Tahun 2019. Penelitian ini menggunakan metode analitik dengan pendekatan Cross Sectional Study untuk mengetahui antara usia kehamilan, ketuban pecah dini dan inersia uteri dengan kejadian keberhasilan induksi persalinan pada ibu bersalin di Rumah Umum Bahagia Tahun 2019 dengan jumlah populasi sebanyak 39 orang dan jumlah sampel 39 orang dengan menggunakan teknik Total Sampling. Dari hasil uji statistik chi-Square (Fisher's Exact Test) di peroleh untuk variabel usia kehamilan nilai p = 0,452>α = 0,05 artinya tidak ada hubungan antara usia kehamilan dengan keberhasilan induksi persalinan. Untuk variabel ketuban pecah dini  nilai p =0,294>α = 0,05  yang artinya tidak ada hubungan antara ketuban pecah dini dengan keberhasilan induksi persalinan. Untuk variabel inersia uteri nilai p =0.016.<α = 0,05 yang  artinya ada hubungan antara inersia uteri dengan keberhasilan induksi persalinan. Kesimpulan dari tiga variabel yaitu usia kehamilan, ketuban pecah dini, inersia uteri, hanya variabel inersia uteri yang berhubungan dengan induksi persalinan di Rumah Sakit umum bahagia tahun 2019.
Hubungan Pengetahuan Ibu Terhadap Pemberian Kolostrum Di Rumkit TK.II Pelamonia Makassar Tahun 2019
Authors: Arifuddin Asyima , Riska Riska Aziz
Published: January 2020

Berdasarkan data yang diperoleh dari Rumkit TK.II Pelamonia pada tahun 2017 jumlah ibu Nifas sebanyak 491 orang ,Tahun 2018 jumlah ibu nifas sebanyak 426 orang dan pada tahun 2019 periode Januari-Mei jumlah ibu nifas sebanyak 133 orang. Tujuan dilakukan penelitian ini adalah untuk mengetahui hubungan antara  pengetahuan ibu terhadap pemberian kolostrum di Rumkit TK.II Pelamonia Makassar 2019.Penelitian ini menggunakan metode analitik dengan pendekatan Cross sectional Study  untuk mengetahui hubungan pengetahuan Ibu terhadap pemberian kolostrum di Rumkit TK.II Pelamonia Makassar dengan jumlah populasi 30 orang dan jumlah sampel 30 orang dengan menggunakan teknik Total Sampling. Dari hasil uji statistik dengan menggunakan uji chi-square (pearson chi-square) diperoleh untuk variabel pengetahuan nilai p = 0,000 < dari a = 0,05, artinya bahwa ada hubungan antara tingkat pengetahuan ibu terhadap pemberian kolostrum. Kesimpulan  yaitu pengetahuan ibu ada  hubungan dengan pemberian kolostrum di  Rumkit TK.II Pelamonia
Faktor Yang Berhubungan Dengan Kejadian Bayi Lahir Prematur di RSUD Syekh Yusuf Gowa Tahun 2019
Authors: Subriani St , T Devy Harmita , A Zhalsyabilah Yunita
Published: January 2020

Berdasarkan data yang diperoleh dari Rekam Medik RSUD Syekh Yusuf Gowa, pada tahun 2018 terdapat 1946 bayi lahir hidup dan pada tahun 2019 periode Januari-Maret terdapat 189 bayi yang lahir hidup. Tujuan dilakukannya penelitian ini adalah untuk mengetahui Faktor yang berhubungan dengan kejadian bayi lahir prematur di RSUD Syekh Yusuf Gowa 2019. Penelitian ini menggunakan metode penelitian analitik dengan menggunakan pendekatan Cross Section Study untuk mengetahui hubungan usia, paritas, anemia ibu dan hipertensi terhadap kejadian Bayi Lahir Prematur di RSUD Syekh Yusuf Gowa dengan jumlah populasi 189 orang dan jumlah sampel 189 orang dengan menggunakan teknik Total Sampling. Responden yang memiliki paritas tinggi terhadap kejadian Bayi Lahir Prematur sebanyak 8 bayi (53,3%) dan yang memiliki paritas rendah terhadap kejadian Bayi Lahir Prematur sebanyak 7 bayi (46,7%). Dari hasil uji statistik dengan menggunakan uji Chi-Square diperoleh  nilai P (0,000) ≤ α (0,05), maka Ho ditolak Ha diterima. Responden yang memiliki umur berisiko terhadap kejadian Bayi Lahir Prematur sebanyak 9 bayi (60%) dan responden yang memiliki umur tidak berisiko terhadap kejadian Bayi Lahir Prematur sebanyak 6 bayi (40%). Dari hasil uji statistik dengan menggunakan uji Chi-Square diperoleh  nilai P (0,04) ≤  α (0,05), maka Ho ditolak dan Ha diterima. Responden dengan ibu anemia terhadap kejadian Bayi Lahir Prematur sebanyak 5 (33,3%) dan responden yang tidak anemia terhadap kejadian Bayi Lahir Prematur sebanyak 10 orang (66,7%). Dari hasil uji statistik dengan menggunakan Chi-Square di peroleh nilai P (0,000) ≤ α (0,05), maka Ho ditolak Ha diterima. Responden dengan hipertensi terhadap kejadian Bayi Lahir Prematur sebanyak 6 (40%) dan responden yang tidak hipertensi terhadap kejadian Bayi Lahir Prematur sebanyak 9 (60%). Dari hasil uji statistik menggunakan Chi-Square (Continuity Correctionb) diperoleh nilai P (0,000) ≤ α (0,05), maka Ho ditolak Ha diterima. Kesimpulan dari keempat variabel yaitu umur, paritas, anemia ibu dan hipertensi, keempat variabel berhubungan terhadap kejadian Bayi Lahir Prematur di RSUD Syekh Yusuf Gowa 2019.
ASSESSING PROCUREMENT IRREGULARITIES IN THE SUPPLY-CHAIN OF GHANAIAN CONSTRUCTION PROJECTS: A SOFT-COMPUTING APPROACH
Authors: Owusu Emmanuel Kingsford , Chan Albert P. C. , Hosseini M. Reza , Nikmehr Bahareh
Published: January 2020

This study examines procurement irregularities, as one of the most unexplored threats in the procurement process of construction projects. It also tests the suppositions associated with the contributions of irregularities to corruption in construction procurement. An expert survey is conducted with 62 construction-related practitioners selected via non-probabilistic sampling in the context of a Ghana, to assess the criticalities of the irregularities. Eighteen irregularities were identified within the context selected for this study. A soft computing technique known as the Fuzzy Synthetic Evaluation (FSE) method is employed to examine the identified irregularities. Other relevant techniques including factor analyses, normalization, and descriptive tools are employed to factorize the identified irregularities and test the hypotheses. Out of the 18 irregularities, 11 were revealed to be critical. The findings reveal that the top three irregularities were: payments for uncompleted works, sourcing of proforma invoices from the same supplier and the lack of proper coordination among key departments. Moreover, four constructs were developed using the identified measurement items. They are administrative-specific, procedural, compliance and contract monitoring irregularities. Out of the four, the topmost critical construct turns out to be compliance irregularities. Theoretically, this study advances the scholarship of construction by shedding lights on the irregularities associated with the procurement processes of construction projects. It also contributes to an in-depth understanding of the noted irregularities. In practical terms, this study contributes to the procurement planning and policy-making process, it assists decision makers in putting in place measures to prevent or extirpate the likelihood of any of the irregularities’ occurrences.
Documenting museum records of West African Coccinellidae (Coleoptera) in Benin and Senegal
Authors: Hounkpati Kwevitoukoui , McHugh Joseph , Niang Abdoul Aziz , Goergen Georg
Published: January 2020

This work provides a preliminary inventory of West African Coccinellidae.

This was based on the West African Coccinellidae (WAC) specimens in the holdings of insect collections at the Laboratoire de Zoologie des Invertébrés Terrestres at the Institut Fondamental d’Afrique Noire Cheikh Anta Diop (IFAN), Senegal and the Biodiversity Center at the International Institute of Tropical Agriculture (IITAB), Benin.

A total of 129 species representing 11 tribes and 40 genera is reported, including one species of the subfamily Microweiseinae and 128 species of the subfamily Coccinellinae. The geographic distribution of collection localities is presented for these species. Cheilomenes lunata (Fabricius, 1775), Cheilomenes propinqua (Mulsant, 1850), Cheilomenes sulphurea (Olivier, 1791), Chnootriba elaterii (Rossi, 1794), Chnootriba similis (Thunberg, 1781), Exochomus laeviusculus Weise, 1909, Hyperaspis delicatula (Mulsant, 1850) and Hyperaspis pumila Mulsant, 1850 are the best represented species in these collections.
Les relations entre la France et l’Italie sous l’angle gastronomique : origines historiques et ressorts contemporains
Authors: Zappalà Daniele
Published: January 2020

La reconnaissance et la construction de la cuisine italienne en France relèvent d’un processus historique et social dont l’imaginaire des Français est un moteur majeur, sur fond d’une communauté culturelle franco-italienne ancienne. L’intensité de la reconnaissance gastronomique franco-italienne pourrait ouvrir des perspectives nouvelles dans le champ de la géopolitique européenne et planétaire du goût.
La critique marxiste du contrat de travail
Authors: Tanghe Fernand
Published: January 2020

La première partie du texte contient un résumé de la critique du contrat de travail telle qu’on peut la dégager de l’œuvre de Marx. Cette critique revient à dire que le contrat de travail est une médiation/réelle et une forme idéologique de l’exploitation capitaliste. Médiation réelle et nécessaire parce que, dans le capitalisme, l’exploitation passe par la sphère de la circulation, où tous les individus sont sujets de droit, libres et égaux. Forme idéologique parce que le contrat, comme figure juridique de la circulation, dissimule la sphère de la production où a lieu l’extorsion de plus-value (exploitation). La critique de Marx est donc centrée autour de l’exploitation (économique). Toutefois, on trouve dans son œuvre, sous forme dominée, une autre problématique concernant le droit : c’est la critique selon laquelle le sujet de droit et le contractualisme constituent une figure de la réification de l’individu par les rapports marchands. Or, c’est cette problématique dominée qu’il s’agit de développer aujourd’hui. Cette voie est esquissée dans la deuxième partie de l’article. A partir des problèmes et des ambiguïtés suscités par la théorie de la plus-value, l’accent est déplacé sur la médiation et la consécration de la dépendance par le contrat (de travail) : aujourd’hui, cette dépendance ne concerne pas seulement la sphère de la production, mais, de plus en plus, la sphère de consommation et les autres domaines de la vie quotidienne. D’autre part, de par son abstraction même, le sujet de droit ne peut pas être réduit à une figure des rapports marchands : par les potentialités politiques qu’il contient et son indétermination historique, il peut devenir moyen de lutte contre la société capitaliste. Finalement, il y a donc une réduction économiste à l’œuvre dans la critique de Marx, qui lui fait manquer aussi la dimension politique du communisme. C’est pourquoi l’article se clôt par un "éloge du politique" et le rappel que l’assomption de cette dimension est indispensable pour le développement d’une critique du droit existant.
Performance Evaluation of Cloud Systems by Switching the Virtual Machines Power Mode Between the Sleep Mode and Active Mode
Authors: Patra Sudhansu Shekhar , Goswami Veena , Mund G. B.
Published: January 2020

Data centers are cost-effective infrastructures for storing large volumes of data and hosting large scale service applications. Cloud computing service providers are rapidly deploying data centers across the world with a huge number of servers and switches. These data centers consume significant amounts of energy, contributing to high operational costs. In this chapter, we study energy savings of data centers by consolidation and switching off of those virtual machines which are not in use. According to this policy, c virtual machines continue serving the customer until the number of idle servers attains the threshold level d; then d idle servers take synchronous vacation simultaneously, otherwise these servers begin serving the customers. Numerical results are provided to demonstrate the applicability of the proposed model for the data center management in particular, to quantify theoretically the tradeoff between the conflicting aims of energy efficiency and Quality of Service (QoS) requirements specified by cloud tenants.