bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of extract from Maclura tricuspidata twig
fermented with Ganoderma lucidum mycelium on adipocyte
differentiation and inflammation in 3T3-L1 cells
Authors: Kim Ki-Man , Park Se-Eun , Kim Seung
Published: July 2023

This study aimed to evaluate the anti-adipogenic and anti-inflammation effects of
extract from Maclura tricuspidata twig fermented with
Ganoderma lucidum mycelium (EMFG) in 3T3-L1 preadipocytes.
3T3-L1 adipocytes were treated with 100, 200, 300 μg/mL of EMFG. The
result showed that EMFG dose-dependently inhibited the accumulation of
intracellular lipid content in differentiated 3T3-L1 adipocytes and enhanced
increase of adiponectin release and inhibition of leptin release. EMFG treatment
reduced expression of adipogenic transcriptional factor such as peroxisome
proliferator-activated receptor γ (PPARγ), CCAAT-enhancer-binding
protein α (C/EBPα). EMFG also decreased production of
lipopolysaccharide (LPS)-induced inflammatory cytokine [tumor necrosis
factor-α (TNF-α), interleukin-6 (IL-6) and monocyte
chemoattractant protein-1 (MCP-1)] and the protein expression of
cyclooxygenase-2 (COX-2) and inducible NOS (iNOS) in differentiated 3T3-L1
adipocytes. The study demonstrated that EMFG inhibited adipogenesis and
inflammation in a dose-dependent manner. These findings suggest that EMFG may
have potential as an anti-obesity and anti-metabolic disease agent that works by
inhibiting adipogenesis and inflammation.
Anti-fatigue effect of a beverage mixture containing red ginseng
and Prunus mume fruit vinegar on high-intensity exercised
rats
Authors: Park Wool-Lim , Kim Jeong-Ho , Seo Kwon-Il
Published: July 2023

New types of vinegar drinks are being processed and developed using various raw
materials. In this study, a beverage containing a mixture of 0.25% red ginseng
extract and 5% Prunus mume fruit vinegar (RPV) was evaluated
for its anti-fatigue effect on high-intensity exercised rats. RPV administration
markedly enhanced running endurance and significantly decreased fatigue-related
serum biomarkers, such as inorganic phosphate, ammonia, and L-lactate, compared
to the other groups. In addition, RPV administration increased glycogen contents
in the liver and muscles and decreased creatine kinase activity in the serum and
muscles. RPV administration also remarkedly increased the activity of lactate in
the muscles. Furthermore, HPLC analysis revealed that main organic acids in RPV
were acetic acid, malic acid, and citric acids. Overall, the results indicate
that RPV improved fatigue recovery in exhausted rats, thus proving a promising
material of functional food to attenuate fatigue.
Surface defect classification of hot-rolled steel strip based on mixed attention mechanism
Authors: Fan Haonan , Dong Qin , Guo Naixuan
Published: July 2023

Purpose

This paper aims to propose a classification method for steel strip surface defects based on a mixed attention mechanism to achieve fast and accurate classification performance. The traditional method of classifying surface defects of hot-rolled steel strips has the problems of low recognition accuracy and low efficiency in the industrial complex production environment.

Design/methodology/approach

The authors selected min–max scaling comparison method to filter the training results of multiple network models on the steel strip surface defect data set. Then, the best comprehensive performance model EfficientNet-B0 was refined. Based on this, the authors proposed two mixed attention addition methods, which include squeeze-excitation spatial mixed module and multilayer mixed attention mechanism (MMAM) module, respectively.

Findings

With these two methods, the authors achieved 96.72% and 97.70% recognition accuracy on the steel strip data set after data augmentation for adapting to the complex production environment, respectively. Using the transfer learning method, the EfficientNet-B0 based on MMAM obtained 100% recognition accuracy.

Originality/value

This study not only focuses on improving the recognition accuracy of the network model itself but also considers other performance indicators of the network, which are rarely considered by many researchers. The authors further improve the intelligent production technique and address this issue. Both methods proposed in this paper can be applied to embedded equipment, which can effectively improve steel strip factory production efficiency and reduce material and time loss.
Ultrasound‐guided pacemaker implantation at the bedside: A lifesaving technique for cardiac emergencies
Authors: Xu Rong‐Quan , Huang Xiao‐Feng , Guo Ping‐Qing , Cai Hong‐Bin , Feng Shao‐Dan , Lin Zhi‐Hong
Published: July 2023

Objective

To investigate the safety and effectiveness of implanting temporary pacemakers using ultrasound‐guidance at the bedside for rescuing patients in case of cardiac emergencies.

Methods

We enrolled 194 patients with cardiac emergencies requiring temporary pacemakers in this study, and randomly assigned them to either a bedside ultrasound‐guided installation group or an electrocardiogram‐guided installation group. There were 105 cases in the bedside ultrasound‐guided installation group, aged approximately 66.3 ± 10.2 years, and 89 cases in the electrocardiogram‐guided installation group, aged approximately 65.8 ± 9.5 years old, and disease composition was similar between the two groups. We then compared the duration of the procedure, success rates, and occurrence of adverse events between the two groups.

Results

The two groups showed similar clinical characteristics. The success rates of venipuncture and temporary pacemaker electrode placement were both 100% in the bedside ultrasound‐guided installation group, compared to 87.8% and 96.7% respectively, in the electrocardiogram‐guided installation group, with a statistically significant difference between the two groups. The duration of puncture was significantly shorter in the bedside ultrasound‐guided installation group than in the electrocardiogram‐guided installation group, with statistically significant differences. Moreover, no adverse events such as hematoma, pneumothorax and electrode dislodgement occurred in the bedside ultrasound‐guided installation group, while 13 cases in the electrocardiogram‐guided installation group experienced adverse events, and the difference was statistically significant.

Conclusions

The bedside installation of temporary pacemakers using ultrasound guidance is a simple, safe, effective, and cost‐efficient procedure that boasts a high success rate, does not involve radiation, and enables accurate placement of the electrode catheter.
Implementation research for developing Civil Registration and Vital Statistics (CRVS) Systems: lessons from Indonesia
Authors: Musadad Dede Anwar , Angkasawati Tri Juni , Usman Yuslely , Kelly Matthew , Rao Chalapati
Published: July 2023

Civil Registration and Vital Statistics (CRVS) systems are the optimal source for data on births, deaths and causes of death for health policy, programme evaluation and research. In Indonesia, indicators such as life expectancy at birth, childhood and maternal mortality rates and cause-specific death rates need to be routinely monitored for national health policy. However, the CRVS system is not yet producing reliable vital statistics, which creates a challenge for evidence-based health action. In 2019, the Indonesian government released a national strategy for the CRVS system, with targets for improved coverage and data quality by 2024. This article describes findings from a programme of formative and implementation research to guide the application of the national strategy. At first, a detailed CRVS assessment and gap analysis were undertaken using an international framework. The assessment findings were used to develop a revised business process model for reporting deaths and their causes at village, subdistrict and district level. In addition, a field instruction manual was also developed to guide personnel in implementation. Two field sites in Java—Malang District and Kudus Regency were selected for pilot testing the reporting procedures, and relevant site preparation and training were carried out. Data compilations for Malang in 2019 and Kudus in 2020 were analysed to derive mortality indicators. High levels of death reporting completeness (83% to 89%) were reported from both districts, along with plausible cause-specific mortality profiles, although the latter need further validation. The study findings establish the feasibility of implementing revised death reporting procedures at the local level, as well as demonstrate sustainability through institutionalisation and capacity building, and can be used to accelerate further development of the CRVS system in Indonesia.
Valproate pregnancy prevention scheme: what are the barriers to enrolling patients and how do we meet them?
Authors: Watila Musa Mamman , James Alistair , Milne Karen , Mackay Graham
Published: July 2023

Background

The UK Medicines Health products Regulation Agency instructs that valproate prescriptions should be restricted in women of childbearing age to those consenting to the Pregnancy Prevention Programme (PPP). We assessed the compliance and barriers to the valproate PPP.

Methods

We retrospectively audited NHS Grampian’s compliance with PPP guidelines among women of childbearing potential prescribed valproate between October 2017 and March 2018. Additionally, we prospectively reviewed new valproate prescriptions from February 2019 to March 2022 and compared this with our retrospective data to assess the effectiveness of our identification process using descriptive statistics.

Results

We identified 351 women retrospectively and 80 women prospectively. Epilepsy, migraine and psychiatry were the main indications. There was a decline in valproate use over the years, particularly for epilepsy. Initially, only 132 (37.6%) met the PPP requirement, and eventually, 81 (23%) stopped the medication. Despite efforts, 38 (10.8%) had contact with secondary care but still did not meet PPP and 100 (28.5%) had no documentation or referral to secondary care. Patients not meeting PPP lacked capacity, most commonly with severe learning difficulties. Women treated for psychiatric purposes were less likely to meet PPP than other indications.

Conclusions

A significant proportion of women continue valproate treatment without meeting the PPP requirement. This is linked to their indication for prescription and their comorbidities. Collaborative input from relevant specialities and primary care is required to fully achieve PPP if a national valproate database is to be established.
Examining barriers and facilitators of HPV vaccination in Nigeria, in the context of an innovative delivery model: a mixed-methods study
Authors: Talabi Odunayo , Gilbert Hannah , Fawzi Mary C Smith , Anorlu Rose , Randall Thomas
Published: July 2023

Background

More than 80% of cervical cancer cases diagnosed globally are in low-income and middle-income countries. In sub-Saharan Africa, where treatment facilities are widely unavailable, it is a leading cause of cancer deaths in women. Human papillomavirus (HPV) vaccination, which is known to prevent almost 90% of cases of cervical cancer, has low uptake in this region, and little is known about the behaviour of those who have been offered the HPV vaccine. This knowledge is critical to guide policy-makers in sub-Saharan Africa on how best to roll out the vaccine and ensure successful and sustainable HPV vaccination programmes.

Methods

To better understand uptake of the HPV vaccine among schoolgirls in Nigeria, we designed a mixed-methods convergent study, with a case–control quantitative arm that recruited caregivers of adolescent schoolgirls as cases (those who accepted vaccination) and controls (those who did not accept vaccination). For the qualitative study, we conducted 10 focus group discussions with of caregivers and 6 in-depth interviews with school administrators, vaccination sponsors and policy-makers.

Results

Those with high awareness of HPV vaccination had three times the odds of uptake (adjusted OR (aOR) 2.6, 95% CI 1.54 to 4.31, p=0.002). Giving HPV vaccines in school was also associated with uptake (aOR 3.1, 95% CI 1.54 to 6.43, p=0.002). Being offered free HPV vaccination was significant in the bivariate analysis (aOR 1.67, 95% CI 1.03 to 2.70, p=0.039) but was marginally significant in the multivariate analysis (aOR 0.63, 95% CI 0.37 to 1.06, p=0.086). Qualitative themes supported these findings, demonstrating that effective awareness and convenience of vaccination could encourage uptake. Key barriers to uptake included lack of affordability and limited availability of vaccines.

Conclusions

Effective awareness, administering HPV vaccines in school and subsidising HPV vaccination costs can improve uptake.
Improved NASM framework for the land application of food processing wash-water and solid residuals
Authors: Dunlop Connor , Abbassi Bassim , Zytner Richard G.
Published: July 2023

The land application of food-processing wash-waters provides valuable nutrients and soil organic matter to agriculture lands if properly applied. Many jurisdictions have processes in place to ensure that land application provides positive benefits while protecting the environment. However, Ontario food processors have indicated that the land application regulations for wastes are overly burdensome and hindering economic opportunities. Therefore, research was completed to identify potential improvements to Ontario’s land application framework.

The research revealed that Ontario has one of the best regulatory frameworks for land application compared to other North American jurisdictions. Ontario’s documents are easy to find and navigate, but the standards are overly burdensome for lower risk sources of waste. For example, high-risk sources for pathogens and heavy metals such as sewage wastewater are grouped with lower risk sources such as food-processing wash-waters. Potential improvements are presented, including decreased sampling frequencies.
Kinase Inhibitor Pulldown Assay Identifies a Chemotherapy Response Signature in Triple-negative Breast Cancer Based on Purine-binding Proteins
Authors: Wang Junkai , Saltzman Alexander B. , Jaehnig Eric J. , Lei Jonathan T. , Malovannaya Anna , Holt Matthew V. , Young Meggie N. , Rimawi Mothaffar F. , Ademuyiwa Foluso O. , Anurag Meenakshi , Kim Beom-Jun , Ellis Matthew J.
Published: July 2023

Triple-negative breast cancer (TNBC) constitutes 10%–15% of all breast tumors. The current standard of care is multiagent chemotherapy, which is effective in only a subset of patients. The original objective of this study was to deploy a mass spectrometry (MS)-based kinase inhibitor pulldown assay (KIPA) to identify kinases elevated in non-pCR (pathologic complete response) cases for therapeutic targeting. Frozen optimal cutting temperature compound–embedded core needle biopsies were obtained from 43 patients with TNBC before docetaxel- and carboplatin-based neoadjuvant chemotherapy. KIPA was applied to the native tumor lysates that were extracted from samples with high tumor content. Seven percent of all identified proteins were kinases, and none were significantly associated with lack of pCR. However, among a large population of “off-target” purine-binding proteins (PBP) identified, seven were enriched in pCR-associated samples (P < 0.01). In orthogonal mRNA-based TNBC datasets, this seven-gene “PBP signature” was associated with chemotherapy sensitivity and favorable clinical outcomes. Functional annotation demonstrated IFN gamma response, nuclear import of DNA repair proteins, and cell death associations. Comparisons with standard tandem mass tagged–based discovery proteomics performed on the same samples demonstrated that KIPA-nominated pCR biomarkers were unique to the platform. KIPA is a novel biomarker discovery tool with unexpected utility for the identification of PBPs related to cytotoxic drug response. The PBP signature has the potential to contribute to clinical trials designed to either escalate or de-escalate therapy based on pCR probability.

Significance:

The identification of pretreatment predictive biomarkers for pCR in response to neoadjuvant chemotherapy would advance precision treatment for TNBC. To complement standard proteogenomic discovery profiling, a KIPA was deployed and unexpectedly identified a seven-member non-kinase PBP pCR-associated signature. Individual members served diverse pathways including IFN gamma response, nuclear import of DNA repair proteins, and cell death.
Discontinuation of Renin-Angiotensin System Inhibitors and Clinical Outcomes in Chronic Kidney Disease: A Systemic Review and Meta-Analysis
Authors: Tang Chen , Wen Xin-Yan , Lv Ji-Cheng , Shi Su-Fang , Zhou Xu-Jie , Liu Li-Jun , Zhang Hong
Published: July 2023

Background: Discontinuation of renin-angiotensin system (RAS) inhibitors is common in patients with chronic kidney disease (CKD), and the potential danger has been reported in several studies. However, a comprehensive analysis has not been conducted. Objectives: This study sought to evaluate the effects of discontinuation of RAS inhibitors in CKD. Method: Relevant studies up to November 30, 2022, were identified in the PubMed, Embase, Web of Science, and Cochrane Library databases. Efficacy outcomes included the composite of all-cause mortality, cardiovascular events, and end-stage kidney disease (ESKD). Results were combined using a random-effects or fixed-effects model, and sensitivity analysis used the leave-one-out method. Results: Six observational studies and one randomized clinical trial including 244,979 patients met the inclusion criteria. Pooled data demonstrated that discontinuation of RAS inhibitors was associated with an increased risk of all-cause mortality (HR 1.42, 95% CI 1.23–1.63), cardiovascular event risk (HR 1.25, 95% CI 1.17–1.22), and ESKD (HR 1.23, 95% CI 1.02–1.49). In sensitivity analyses, the risk for ESKD was reduced. Subgroup analysis showed that the risk of mortality was more pronounced in patients with eGFR above 30 mL/min/m2 and in patients with hyperkalemia-related discontinuation. In contrast, patients with eGFR below 30 mL/min/m2 were at great risk of cardiovascular events. Conclusions: The discontinuation of RAS inhibitors in patients with CKD was associated with a significantly increased risk of all-cause mortality and cardiovascular events. These data suggest that RAS inhibitors should be continued in CKD if the clinical situation allows.
Multimodal Retinal Imaging in Patients with Diabetes Mellitus and Association with Cerebrovascular Disease
Authors: Vujosevic Stela , Fantaguzzi Francesca , Salongcay Recivall , Brambilla Marco , Torti Emanuele , Cushley Laura , Limoli Celeste , Nucci Paolo , Peto Tunde
Published: July 2023

Introduction: This study aimed to evaluate the association between macular optical coherence tomography angiography (OCT-A) metrics, characteristics of ultrawide field (UWF) imaging, and cerebrovascular disease in patients with diabetes mellitus (DM) with different stages of diabetic retinopathy (DR). Methods: 516 eyes of 258 DM patients were enrolled in two centers (Milan and Belfast). UWF color fundus photos (CFPs) were obtained with Optos California (Optos, PLC) and graded for both DR severity and predominantly peripheral lesions presence (>50% of CFP lesions) by two independent graders. OCT-A (3 × 3 mm), available in 252 eyes of 136 patients, was used to determine perimeter, area, and circularity index of the foveal avascular zone and vessel density (VD); perfusion density (PD); fractal dimension on superficial, intermediate (ICP), and deep capillary plexuses; flow voids (FVs) in the choriocapillaris. Results: Out of 516 eyes, 108 eyes (20.9%) had no DR, and 6 eyes were not gradable. The remaining 402 eyes were as follows: 10.3% (53) had mild nonproliferative DR (NPDR), 38.2% (197) had moderate NPDR, 11.8% (61) had severe NPDR, and 17.6% (91) had proliferative DR. A worse DR stage was associated with a history of stroke (p = 0.044). Logistic regression analysis after taking into account sex, type of DM, age, DM duration, and OCT-A variables found that PD and VD on ICP were significantly associated with presence of stroke and DR severity. Conclusion: OCT-A metrics show an association with the presence of cerebrovascular complications, providing potentially useful parameters to estimate vascular risk in patients with DM.
Reimagining the Value of Brachial-Ankle Pulse Wave Velocity as a Biomarker of Cardiovascular Disease Risk—A Call to Action on Behalf of VascAgeNet
Authors: Stone Keeron , Veerasingam Dave , Meyer Michelle L. , Heffernan Kevin S. , Higgins Simon , Maria Bruno Rosa , Bueno Celia Alvarez , Döerr Marcus , Schmidt-Trucksäss Arno , Terentes-Printzios Dimitrios , Voicehovska Jūlija , Climie Rachel E. , Park Chloe , Pucci Giacomo , Bahls Martin , Stoner Lee ,   On behalf of the Network for Research in Vascular Ageing (VascAgeNet)
Published: July 2023

This review critiques the literature supporting clinical assessment and management of cardiovascular disease and cardiovascular disease risk stratification with brachial-ankle pulse wave velocity (baPWV). First, we outline what baPWV actually measures—arterial stiffness of both large central elastic arteries and medium-sized muscular peripheral arteries of the lower limb. Second, we argue that baPWV is not a surrogate for carotid-femoral pulse wave velocity. While both measures are dependent on the properties of the aorta, baPWV is also strongly dependent on the muscular arteries of the lower extremities. Increased lower-extremity arterial stiffness amplifies and hastens wave reflections at the level of the aorta, widens pulse pressure, increases afterload, and reduces coronary perfusion. Third, we used an established evaluation framework to identify the value of baPWV as an independent vascular biomarker. There is sufficient evidence to support (1) proof of concept; (2) prospective validation; (3) incremental value; and (4) clinical utility. However, there is limited or no evidence to support (5) clinical outcomes; (6) cost-effectiveness; (8) methodological consensus; or (9) reference values. Fourth, we address future research requirements. The majority of the evaluation criteria, (1) proof of concept, (2) prospective validation, (3) incremental value, (4) clinical utility and (9) reference values, can be supported using existing cohort datasets, whereas the (5) clinical outcomes and (6) cost-effectiveness criteria require prospective investigation. The (8) methodological consensus criteria will require an expert consensus statement. Finally, we finish this review by providing an example of a future clinical practice model.
Chionanthus monteazulensis (Oleaceae), a new species from the campo rupestre of Espinhaço Range, Brazil
Authors: ALVARENGA ZAVATIN DANILO , BAPTISTA PEREIRA ALMEIDA ROBERTO , RAMOS RENATO , LOMBARDI JULIO ANTONIO
Published: July 2023

The new species Chionanthus monteazulensis, from Minas Gerais State, Brazil, is here described and illustrated. It differs from somewhat similar C. fluminensis by the inflorescence size, two stamens (vs. four), the smaller and orbicular or wide-elliptic blades, and the smaller petals and fruits.
4. Julie Jeanne Éléonore de Lespinasse
Authors: Isbell John Claiborne
Published: July 2023

Destins de femmes is the first comprehensive overview of French women writers during the turbulent period of 1750-1850. John Isbell provides an essential collection that illuminates the impact women writers had on French literature and politics during a time marked by three revolutions, the influx of Romantic art, and rapid technological change.

Each of the book’s thirty chapters introduces a prominent work by a different female author writing in French during the period, from Germaine de Staël to George Sand, from the admired salon libertine Marie du Deffand to Flora Tristan, tireless campaigner for socialism and women’s rights. Isbell draws from multi-genre writers working in prose, poetry and correspondence and addresses the breadth of women’s contribution to the literature of the age. Isbell also details the important events which shaped the writers’ lives and contextualises their work amidst the liberties both given and taken away from women during the period.

This anthology fills a significant gap in the secondary literature on this transformative century, which often overlooks women who were working and active. It invites a further gendered investigation of the impact of revolution and Romanticism on the content and nature of French women’s writing, and will therefore be appropriate for both general readers, students, and academics analysing history and literature through a feminist lens.
7. Stéphanie Félicité, Marquise de Sillery, Comtesse de Genlis
Authors: Isbell John Claiborne
Published: July 2023

Destins de femmes is the first comprehensive overview of French women writers during the turbulent period of 1750-1850. John Isbell provides an essential collection that illuminates the impact women writers had on French literature and politics during a time marked by three revolutions, the influx of Romantic art, and rapid technological change.

Each of the book’s thirty chapters introduces a prominent work by a different female author writing in French during the period, from Germaine de Staël to George Sand, from the admired salon libertine Marie du Deffand to Flora Tristan, tireless campaigner for socialism and women’s rights. Isbell draws from multi-genre writers working in prose, poetry and correspondence and addresses the breadth of women’s contribution to the literature of the age. Isbell also details the important events which shaped the writers’ lives and contextualises their work amidst the liberties both given and taken away from women during the period.

This anthology fills a significant gap in the secondary literature on this transformative century, which often overlooks women who were working and active. It invites a further gendered investigation of the impact of revolution and Romanticism on the content and nature of French women’s writing, and will therefore be appropriate for both general readers, students, and academics analysing history and literature through a feminist lens.
10. Marie Louise Élisabeth Vigée Le Brun
Authors: Isbell John Claiborne
Published: July 2023

Destins de femmes is the first comprehensive overview of French women writers during the turbulent period of 1750-1850. John Isbell provides an essential collection that illuminates the impact women writers had on French literature and politics during a time marked by three revolutions, the influx of Romantic art, and rapid technological change.

Each of the book’s thirty chapters introduces a prominent work by a different female author writing in French during the period, from Germaine de Staël to George Sand, from the admired salon libertine Marie du Deffand to Flora Tristan, tireless campaigner for socialism and women’s rights. Isbell draws from multi-genre writers working in prose, poetry and correspondence and addresses the breadth of women’s contribution to the literature of the age. Isbell also details the important events which shaped the writers’ lives and contextualises their work amidst the liberties both given and taken away from women during the period.

This anthology fills a significant gap in the secondary literature on this transformative century, which often overlooks women who were working and active. It invites a further gendered investigation of the impact of revolution and Romanticism on the content and nature of French women’s writing, and will therefore be appropriate for both general readers, students, and academics analysing history and literature through a feminist lens.
12. Sophie de Grouchy or Sophie de Condorcet
Authors: Isbell John Claiborne
Published: July 2023

Destins de femmes is the first comprehensive overview of French women writers during the turbulent period of 1750-1850. John Isbell provides an essential collection that illuminates the impact women writers had on French literature and politics during a time marked by three revolutions, the influx of Romantic art, and rapid technological change.

Each of the book’s thirty chapters introduces a prominent work by a different female author writing in French during the period, from Germaine de Staël to George Sand, from the admired salon libertine Marie du Deffand to Flora Tristan, tireless campaigner for socialism and women’s rights. Isbell draws from multi-genre writers working in prose, poetry and correspondence and addresses the breadth of women’s contribution to the literature of the age. Isbell also details the important events which shaped the writers’ lives and contextualises their work amidst the liberties both given and taken away from women during the period.

This anthology fills a significant gap in the secondary literature on this transformative century, which often overlooks women who were working and active. It invites a further gendered investigation of the impact of revolution and Romanticism on the content and nature of French women’s writing, and will therefore be appropriate for both general readers, students, and academics analysing history and literature through a feminist lens.
16. Henriette Lucie Dillon, Marquise de La Tour-du-Pin Gouvernet
Authors: Isbell John Claiborne
Published: July 2023

Destins de femmes is the first comprehensive overview of French women writers during the turbulent period of 1750-1850. John Isbell provides an essential collection that illuminates the impact women writers had on French literature and politics during a time marked by three revolutions, the influx of Romantic art, and rapid technological change.

Each of the book’s thirty chapters introduces a prominent work by a different female author writing in French during the period, from Germaine de Staël to George Sand, from the admired salon libertine Marie du Deffand to Flora Tristan, tireless campaigner for socialism and women’s rights. Isbell draws from multi-genre writers working in prose, poetry and correspondence and addresses the breadth of women’s contribution to the literature of the age. Isbell also details the important events which shaped the writers’ lives and contextualises their work amidst the liberties both given and taken away from women during the period.

This anthology fills a significant gap in the secondary literature on this transformative century, which often overlooks women who were working and active. It invites a further gendered investigation of the impact of revolution and Romanticism on the content and nature of French women’s writing, and will therefore be appropriate for both general readers, students, and academics analysing history and literature through a feminist lens.
17. Marie Sophie Risteau Cottin
Authors: Isbell John Claiborne
Published: July 2023

Destins de femmes is the first comprehensive overview of French women writers during the turbulent period of 1750-1850. John Isbell provides an essential collection that illuminates the impact women writers had on French literature and politics during a time marked by three revolutions, the influx of Romantic art, and rapid technological change.

Each of the book’s thirty chapters introduces a prominent work by a different female author writing in French during the period, from Germaine de Staël to George Sand, from the admired salon libertine Marie du Deffand to Flora Tristan, tireless campaigner for socialism and women’s rights. Isbell draws from multi-genre writers working in prose, poetry and correspondence and addresses the breadth of women’s contribution to the literature of the age. Isbell also details the important events which shaped the writers’ lives and contextualises their work amidst the liberties both given and taken away from women during the period.

This anthology fills a significant gap in the secondary literature on this transformative century, which often overlooks women who were working and active. It invites a further gendered investigation of the impact of revolution and Romanticism on the content and nature of French women’s writing, and will therefore be appropriate for both general readers, students, and academics analysing history and literature through a feminist lens.
19. Claire Louisa Rose Bonne, Duchesse de Duras
Authors: Isbell John Claiborne
Published: July 2023

Destins de femmes is the first comprehensive overview of French women writers during the turbulent period of 1750-1850. John Isbell provides an essential collection that illuminates the impact women writers had on French literature and politics during a time marked by three revolutions, the influx of Romantic art, and rapid technological change.

Each of the book’s thirty chapters introduces a prominent work by a different female author writing in French during the period, from Germaine de Staël to George Sand, from the admired salon libertine Marie du Deffand to Flora Tristan, tireless campaigner for socialism and women’s rights. Isbell draws from multi-genre writers working in prose, poetry and correspondence and addresses the breadth of women’s contribution to the literature of the age. Isbell also details the important events which shaped the writers’ lives and contextualises their work amidst the liberties both given and taken away from women during the period.

This anthology fills a significant gap in the secondary literature on this transformative century, which often overlooks women who were working and active. It invites a further gendered investigation of the impact of revolution and Romanticism on the content and nature of French women’s writing, and will therefore be appropriate for both general readers, students, and academics analysing history and literature through a feminist lens.
28. Marie Catherine Sophie de Flavigny, Comtesse d’Agoult [Daniel Stern]
Authors: Isbell John Claiborne
Published: July 2023

Destins de femmes is the first comprehensive overview of French women writers during the turbulent period of 1750-1850. John Isbell provides an essential collection that illuminates the impact women writers had on French literature and politics during a time marked by three revolutions, the influx of Romantic art, and rapid technological change.

Each of the book’s thirty chapters introduces a prominent work by a different female author writing in French during the period, from Germaine de Staël to George Sand, from the admired salon libertine Marie du Deffand to Flora Tristan, tireless campaigner for socialism and women’s rights. Isbell draws from multi-genre writers working in prose, poetry and correspondence and addresses the breadth of women’s contribution to the literature of the age. Isbell also details the important events which shaped the writers’ lives and contextualises their work amidst the liberties both given and taken away from women during the period.

This anthology fills a significant gap in the secondary literature on this transformative century, which often overlooks women who were working and active. It invites a further gendered investigation of the impact of revolution and Romanticism on the content and nature of French women’s writing, and will therefore be appropriate for both general readers, students, and academics analysing history and literature through a feminist lens.
Is violence against men a problem in Sri Lanka?
Authors: Jayaratne Sashini , Wijewardena Kumudu
Published: July 2023

Background:

Gender-based violence (GBV) among men is a universally present phenomenon that is mostly unacknowledged. The relative lack of research in this area leads to a deficiency of evidence ascribing due recognition to GBV among men. This, in turn, leads to not identifying it as a social problem, hence, poor development of resources for victims as well as poor help-seeking behaviour patterns are prevalent, especially in Southeast Asia.

Aims:

We aimed to determine the prevalence of GBV among men in Colombo, Sri Lanka.

Method:

A descriptive cross-sectional analytical community survey was conducted to explore GBV against 1280 Sinhala-speaking men, selected using a multistage cluster sampling method in Colombo district, Sri Lanka. The GBV among men questionnaire (GBVMQ) was developed and culturally validated. A multiple logistic regression model was developed and nine correlates of GBV were identified and adjusted odds ratios estimated.

Results:

The prevalence of GBV was 35.8% (95% CI 33.1 -38.6). The prevalence of Verbal GBV was 34.7% (95% CI 32.1 -37.5). Childhood sexual abuse was 7.6% (95% CI 6.2 -9.2). Being subjected to ridicule as cowardly or unmanly (AOR = 25.3, 95% CI 5.58 -114.7, P<0.0010), Childhood sexual abuse (AOR = 4.4, 95% CI 1.73 -11.09, P = 0.002) showed positive associations with statistical significance.

Conclusion:

The results highlight the importance of having services for men as well as women. Enabling inclusiveness of men in mandates of state and private institutions catering for GBV would be a strategy in moving forward for Sri Lanka.
Shakespearean comedy and Japanese (wo)men's Shakespeare: A refraction for the twenty-first century
Authors: Gallimore Daniel
Published: July 2023

Two adaptations of Shakespeare comedies between 2008 and 2010 by the Tokyo-based all-male Studio Life company coincided with the better-known all-male Shakespeares directed by Ninagawa Yukio (based just outside Tokyo) and a moment of rising awareness of gender issues in Japanese society. This article explores the role of Studio Life's (and Ninagawa's) translator Matsuoka Kazuko, arguing that just as the all-male format rendered the chauvinistic aspects of Shakespearean comedy more palatable to a mainly female audience, so too does Matsuoka's achievement as the first female translator of Shakespeare's complete plays reveal the possibility of a Japanese woman ‘becoming’ Shakespeare.
Mitigation of airborne transmission of COVID virus between occupants in a confined room with an air purifier
Authors: Wang Chenhua , Li Chengjun , Yu Chuck W , Wang Hanqing
Published: July 2023

This study evaluated the effect of ventilation rate and air supply angle of an air purifier using computational fluid dynamics to determine the dispersion of airborne COVID virus exhaled by an infected person. The risk of infection for an occupant was determined based on the virus concentration in the active area and accumulated particle dose within the breathing zone by varying the ventilation parameters. The air purifier was found to provide a local dilution and would block the development of an expiratory jet for a short time to reduce transmission risk. Compared to the case without an air purifier, the maximum reductions were 94.27% in the accumulated dose and 53.2% in the particle count concentration. In the breathing area, the larger air supply angle (90° > 60° > 30°) is better when the ventilation rate was 27.0 m3/h and 40.5 m3/h. Otherwise, 60° air supply angle is preferable where the ventilation rate was 54.0 m3/h. Assessing the results with the grey relational analysis revealed that the relational degree for particle count concentration was greater by varying the ventilation rate than by varying the air supply angle. However, the relational degree according to the accumulated dose was greater by varying the air supply angle than by increasing the ventilation rate. These findings may provide an important control strategy to effectively mitigate the risk of infection in a confined room by using an air purifier.
Preparation and characterization of graphene antibacterial phase change energy storage viscose fibers
Authors: Zhao Zhou , Du Shichang , Li Bei , Li Yan , Wang Jinmei , Ren Jun
Published: July 2023

In this work, viscose fiber with antibacterial and phase change energy storage was made by microcapsule technology and wet spinning. Graphene oxide was used to enhance the thermal conductivity and antimicrobial properties. The heat preservation performance of graphene antibacterial phase change energy storage viscose fiber was determined by flat type fabric temperature protector and differential scanning calorimetry. The result of heat preservation test shows that the fiber has a good heat preservation property The antibacterial property, far-infrared property, mechanical properties, and the structures were also characterized. The enthalpy of exothermic & endothermic phase transition reached about 10 mJ/mg. According to the result of antibacterial test, the fiber had good antibacterial properties. The distribution of phase change microcapsules and graphene in fibers was analyzed by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The strength and elongation of antibacterial phase change viscose fiber were found suitable for underwear garments fabrics and filling storage sheet. Combined with the electron microscope photograph and strength test results, the addition of graphene and phase change microcapsules has little effect on the mechanical properties of fibers, and can be used for industrial production.
The Development and Integration of a Safety Officer Role to Facilitate Prevention of COVID-19 Virus Transmission in an Adult Inpatient Rehabilitation Setting Using Collaborative Change Leadership Methodology
Authors: Donaghy Siobhan , Shaffer Jennifer , Schneider Susan
Published: July 2023

Background:

With the onset of the COVID-19 pandemic, a large urban academic hospital responded by creating the temporary role of a “Safety Officer (SO).” The key task of the SO role was to supervise staff donning and doffing personal protective equipment (PPE) and provide real-time feedback on their performance. The support for safe donning and doffing would contribute to staff well-being by reducing their fear of infection transmission.

Methods:

A Collaborative Change Leadership (CCL) approach was used to facilitate the development, implementation, and evaluation of the role. This included an iterative feedback process with clinicians and safety officers to continually refine the role.

Findings:

Feedback indicated value in the initiative as increasing staff confidence about preventing virus transmission, as well as their sense of safety at work. Areas for future improvement included additional communication strategies for interprofessional teams and external partners, as well as planning around logistics to better support the safety officers in performing this new, temporary role.

Conclusions/Application to Practice:

The Safety Officer role was able to help alleviate concerns regarding potential infection transmission and contribute positively to staff well-being.
Expected Health Benefits of SGLT-2 Inhibitors and GLP-1 Receptor Agonists in Older Adults
Authors: Dadwani Rahul S. , Wan Wen , Skandari M. Reza , Huang Elbert S.
Published: July 2023

Background. Older and sicker adults with type 2 diabetes (T2D) were underrepresented in randomized trials of glucagon-like peptide 1 receptor-agonist (GLP1RA) and sodium-glucose cotransporter 2 inhibitors (SGLT2I), and thus, health benefits are uncertain in this population. Objective. To assess the impact of age, health status, and life expectancy in older adults with T2D on health benefits of GLP1RA and SGLT2I. Design. We used the United Kingdom Prospective Diabetes Study (UKPDS) model to simulate lifetime health outcomes. We calibrated the UKPDS model to improve mortality prediction in older adults using a common geriatric prognostic index. Participants. National Health and Nutrition Examination Survey 2013–2018 participants 65 y and older with T2D, eligible for GLP1RA or SGLT2I according to American Diabetes Association guidelines. Interventions. GLP1RA or SGLT2I use versus no additional medication. Main Measures. Lifetime complications and weighted life-years (LYs) and quality-adjusted life-years (QALYs) across overall treatment arms and life expectancies. Key Results. The overall older adult population was predicted to experience significant health benefits from GLP1RA (+0.29 LY [95% confidence interval: 0.27, 0.31], +0.15 QALYs [0.14, 0.16]) and SGLT2I (+0.26 LY [0.24, 0.28], +0.13 QALYs [0.12, 0.14]) as compared with no added medication. However, expected benefits declined in subgroups with shorter life expectancies. Participants with <4 y of life expectancy had minimal gains of <0.05 LY and <0.03 QALYs from added medication. Accounting for injection-related disutility, GLP1RA use reduced QALYs (−0.03 QALYs [−0.04, −0.02]). Conclusions. While GLP1RA and SGLT2I have substantial health benefits for many older adults with type 2 diabetes, benefits are not clinically significant in patients with <4 y of life expectancy. Life expectancy and patient preferences are important considerations when prescribing newer diabetes medications.

Highlights

On average, older adults benefit significantly from SGLT2I and GLP1RA use. However, the benefits of these drugs are not clinically significant among older patients with life expectancy less than 4 y. There is potential harm in injectable GLP1RA use in the oldest categories of adults with type 2 diabetes. Heterogeneity in life expectancy and patient preferences for injectable versus oral medications are important to consider when prescribing newer diabetes medications
Let’s Play: Including Students With Disabilities in Ensembles
Authors: Draper Ellary A.
Published: July 2023

In general music classes, students participate in a variety of musical experiences, including ensembles. These may include classroom experiences playing instruments or singing as a group, or in more long-term performance-based experiences such as a musical or program. It is important that students with disabilities participate meaningfully in these experiences alongside their same-aged peers. To ensure students with disabilities are successful, teachers need to be purposeful in their classroom instruction during ensemble experiences as well as in their preparation for performances.
Home Literacy Environment and Literacy Development of Appalachian Preschool Children with Disabilities
Authors: Rahn Naomi L. , Coogle Christan Grygas , Ottley Jennifer R. , Storie Sloan O. , Collier Terri , Cook Ami , Cottrill Shannon , Hicks Kelly , McNeil Kimary , Miltenberger Margaret , Roberts David , Toppe Mollie , Sears Lesley , Trivette Carol
Published: July 2023

A variety of systemic inequities place young children from Appalachian communities in the United States at greater risk for poor academic outcomes than children in other parts of the country. Young children with disabilities are at increased risk for poor academic outcomes because of similar inequities and their need for more intensive learning opportunities. The purpose of this study was to examine associations between early literacy skills and home literacy environment of Appalachian preschool children with disabilities. We completed an online literacy screening tool with 57 children between 3 and 6 years of age who had an Individualized Education Program. Parents completed a questionnaire measuring home literacy environment (parenting beliefs and practices). Children’s scores on the screening tool were not associated with parent reading beliefs but were associated with modeling writing and communication. Neither parent beliefs nor practices were predictive of children’s literacy screening scores. Implications for research and practice are discussed.