bluuebunny/crossref_metadata_2025 huggingface dataset:
Concave and convex small radius bending behavior of single and multiple layers reinforcement fabrics
Authors: Kanz Philippe , Robitaille Francois
Published: April 2024

Multilayer reinforcement fabrics are increasingly used for manufacturing structural polymer composites. In liquid molding processes, dry reinforcement fabrics are draped on a mold first, and infused with a liquid resin such as an epoxy in a subsequent manufacturing step. This presents major advantages in terms of operational flexibility and costs. However, draping multilayer reinforcement fabrics on complex mold geometries is challenging. Small radius mold corners constitute a major manufacturing challenge as they lead to variability in dry fabric positioning and resin-rich corners in polymer composite parts. Spring-back of fabrics bent over or into single curvature mold corners is a widespread industrial concern. However, contrary to draping over double-curvature surfaces, bending spring-back from convex or concave single-curvature corners has received very limited attention. No testing method is available. This paper quantifies reinforcement fabric bending spring-back. Single and multiple layer stacks were bent along three directions over convex and into concave 90° corners with five radii spanning 1.59 mm to 12.70 mm. In all cases, five replicated tests enabled variability quantification. Fabric stacks were also quantified using cantilevered bending tests for comparison purposes. Mold radius was found to affect the behavior to a larger extent than testing direction, number of layers or use of a binder.
Antimicrobial treatments with chitosan microencapsulated angelica (Angelica archangelica) and marsh Labrador tea (Rhododendron tomentosum) supercritical CO2 extracts in linen-cotton jacquard woven textiles
Authors: Kunnas Susan , Tienaho Jenni , Holmbom Thomas , Sutela Suvi , Liimatainen Jaana , Kaipanen Kalle , Jääskeläinen Ritva , Sääski Soile , Korpinen Risto I
Published: April 2024

In this study antimicrobial linen-cotton jacquard textiles were manufactured using green chemistry methods. The functionalization of the fabrics was executed by impregnating chitosan microencapsulated bio-based oils from angelica ( Angelica archangelica L.) (AAC) and marsh Labrador tea ( Rhododendron tomentosum Harmaja) (MLTC) obtained with pilot scale supercritical carbon dioxide extraction. The chemical compositions of the extracts of angelica and marsh Labrador tea were analyzed by a combination of gas chromatography and mass spectrometry. The antimicrobial activities of the extracts, AAC and MLTC microcapsules, and the microencapsulated textiles (AAC and MLTC textiles) were analyzed against gram-positive Staphylococcus aureus and gram-negative Escherichia coli bacteria, dimorphic yeast Candida albicans and filamentous mold Aspergillus brasiliensis. The AAC textile proved 40% inhibition against S. aureus, whereas the MLTC textile demonstrated 43.8% and 51.7% inhibition against both S. aureus and E. coli, respectively. Although the chitosan shell material itself indicated mild activity against both bacterial strains, the extracts increased the antibacterial activities in microencapsulated textiles. In addition, the antifungal impact of the MLTC textile was demonstrated against A. brasiliensis. According to the Fourier transform infrared spectroscopy with attenuated total reflection and field emission scanning electron microscopy analyses, covalent bonding between the microcapsules and textile fibers was established with citric acid as a cross-linker. The antimicrobial activity was also shown to persist in the MLTC textiles after six domestic washing cycles.
Association of Caffeine Daily Dose With Respiratory Outcomes in Preterm Neonates: A Retrospective Cohort Study
Authors: Rauf Shahzad , Shah Samar , Bibi Zainab , Munir Rabiya , Jiskani Hamna , Ahmad Saeed , Mir Shah Syed Adil , Bibi Aysha , Fasih Ahmad Hafiz , Hussain Kashif , Ariff Shabina , Ambreen Gul
Published: April 2024

Apnea and poor respiratory drive increase the risk of extubation failure (EF) and prolonged invasive mechanical ventilation (IMV) in preterm neonates (pre-nates) with respiratory distress. Caffeine citrate (CC) is often prescribed for pre-nates in doses of 5–10 mg/kg in 24 h. This study aimed to evaluate the most effective dosage regimen (5 mg/kg/day vs >5-10 mg/kg/day) to prevent apnea and EF with minimal caffeine-associated potential side effects (CC-APSEs) in pre-nates. This one-year retrospective cohort study included all the eligible neonates admitted to NICU and received CC-therapy till 28 days of life (DOL) or discharge. Based on CC-daily dose formed LD-caffeine-group (5 mg/kg/day) and HD-caffeine-group (>5-10 mg/kg/day). Antenatal, prenatal, and postnatal characteristics, CC-regimen, comorbidities, and CC-APSEs were compared between the groups. Predictors of apnea and EF were analyzed through logistic regression. There were 181 and 72 neonates in the LD and HD-caffeine-groups respectively. In HD-caffeine-group daily CC-dose was 7 to 7.5 mg/kg/day in 93% of neonates and >7.5 to 10 mg/kg/day in only 7%. Significantly fewer neonates experienced apnea and EF in the HD-caffeine-group till 28DOL or discharge. This difference was even greater in the subgroup of ≤28 weeks GA (15.6% vs 40.0%; P < .01). In HD-caffeine-group the incidence of severe/moderate-BPD was significantly lower and the frequency of CC-APSEs was higher. Multivariate analysis showed that; the smaller the GA higher the risk of apnea (AOR = 0.510, 95% CI 0.483-0.999) and EF (AOR = 0.787, 95% CI 0.411-0.997). The HD-caffeine was inversely associated with developing apnea (AOR = 0.244, 95% CI 0.053-0.291) and EF (AOR = 0.103, 95% CI 0.098-2.976). IMV-duration before extubation (AOR = 2.229, 95% CI 1.672-2.498) and severe/moderate-BPD (AOR = 2.410, 95%CI 1.104-2.952) had a high risk of EF. Initiating early HD-caffeine may prevent apnea and extubation failure in preterm neonates. Optimization of caffeine initiation time and dosages can be a safe and feasible approach to decrease the burden of neonatal respiratory morbidities.
Medicare Volume Growth and Shift in Payments From Physicians to Non-Physician Practitioners Under Statutory Budget Neutrality
Authors: Christensen Eric W. , Nicola Gregory N. , Rula Elizabeth Y. , Nicola Lauren P. , Hirsch Joshua A.
Published: April 2024

Volume increases, inflation, statutory freezes in physician payments, and the budget neutrality requirement for the Medicare Physician Fee Schedule have resulted in persistent inflation-adjusted conversion factor decreases. This study aimed to determine if relative value unit (RVU) volume increases on a per beneficiary basis has counteracted conversion factor decreases and inflation to maintain Medicare reimbursement per beneficiary, overall and across specialties. Using aggregated data for 100% of Medicare part B claims (2005-2021), we computed the percentage change in reimbursement per beneficiary, nominal and inflation-adjusted, by specialty. These trends were then adjusted by separately holding constant RVUs per beneficiary and the conversion factor to demonstrate the impact of budget neutrality. Inflation-adjusted reimbursement per beneficiary increased 9.9% over the 2005 to 2021 period; this trend encapsulated a 64.8% increase in RVUs per beneficiary, offsetting a 33.6% inflation-adjusted conversion factor decline. RVU changes per beneficiary varied widely across clinicians (+45.5% for physicians to +328.2% for non-physician practitioners) and by specialty (−36.1% for cardiac surgery to +1106% for nurse practitioners). Given RVU increases, conversion factor decreases, and inflation combined, reimbursement per beneficiary decreased 2.3% for physicians and increased 16.3% for limited-license physicians and 206.5% for non-physician practitioners. Overall, increased RVU volume per beneficiary has offset conversion factor declines within the budget neutral system. However, substantial redistribution has occurred across provider types, with reimbursement declining slightly for physicians while tripling for non-physician practitioners. Certain physician specialties, particularly procedural specialties, have declined most. Future research should assess the impact of specialty-specific reimbursement changes on patients’ access to care.
Ethopolitical media: Organizing Assistive Technology, disability and care in the platform society
Authors: Napolitano Domenico , Sicca Luigi Maria
Published: April 2024

In this paper we prompt a re-reading of Assistive Technology (AT) as a media system that organizes disability in the framework of digital health-care and the platform society. Drawing on disability media studies and organization studies, we investigate how the arrival of big tech and digital platforms in the field of AT reconfigures ways to account for, classify and potentially discriminate against disability. We argue that this new configuration can be explained as a shift from a biopolitical model – oriented toward disability normalization – to an ethopolitical model, oriented toward optimization and health enhancement. In the conclusions, we put forward the concept of ethopolitical media and discuss the implications of this for wider debates in media and cultural studies which deal with the relationship between media, health, and self-care.
Drug Dispensation by ‘Signature Pharmacists’ in South Asia
Authors: Lassi Nicholas
Published: April 2024

The phenomenon of ‘signature pharmacists’ in South Asia has allowed allopathic prescription medication to be dispensed without the necessary medical knowledge, specifically of drug interactions, dosages and side effects. This practice, in which qualified pharmacists delegate their professional inputs to often unqualified and unsupervised sales staff, persists due to complicity among pharmacists, other healthcare professionals and regulatory officials. The article discusses the extent of this significant risk to public health in South Asia and argues that pharmacy enforcement and education standards should be reformed to address these huge challenges to ensure consumer protection and the general public’s welfare. While the advice is that regulatory authorities should intensify their supervision and inspection efforts to ensure registered pharmacists actively participate in regular pharmacy operations, the article also identifies predicaments related to corruption that are difficult to tackle.
Segmental differences in daytime changes of leg volume
Authors: Caggiati Alberto , Caggiati Lorenza , Bastiani Luca , Mosti Giovanni
Published: April 2024

Background

The aim of our study was to comparatively assess volume changes related to daily occupation of the whole leg (WLv), of the lower leg (LLv) and of the upper leg (ULv) in subject with no venous and lymphatic disorders.

Method

WLv, LLv, and Ulv were evaluated by water displacement volumetry (WDV) in the morning and in the evening in 20 healthy subjects.

Results

In the legs with occupational edema (OE), WLv increased by 7.07%, LLv by 5.25%, and ULv by 9.80%. In legs without clear OE, WLv increased by 2.41%, LLv by 1.35, and ULv by 3.38%.

Conclusions

Surprisingly, the increase of ULv was greater than that of LLv. An evening increase in the leg volume also occurred in legs with no clear OE. In our series, a clinically evident OE was related to an increase of the WLv, LLv, and ULv greater than 5.83%, 8.68%, and 1.88%, respectively.
Adolescents’ Beliefs About Sex: The Moderating Effects of Peer Attitudes
Authors: Ching Kimiko , Tilak Shantanu , Allsop Yvonne , Anderman Eric M.
Published: April 2024

Peer beliefs and attitudes play a prominent role in adolescent behaviors. Various curricula have been developed to teach students about sexual health from a skills-based perspective with successful, lasting effects. This study examined how adolescents’ expectancies for success in and values held for a sexual health curriculum are related to their attitudes toward waiting to have sex, attitudes toward using a condom, self-efficacy in negotiating condom use, self-efficacy in refusal skills, and self-efficacy in navigating tricky situations, depending on their perceptions of their peers’ attitudes. Results indicate that perceived peer attitudes toward waiting to have sex were a significant moderator, more so than peer attitudes about condom use. Additionally, results suggest that sex plays a role in students’ sexual health beliefs and self-efficacies. Future work should examine further explanatory paths and influences such as caregivers.
Machine learning and new insights for breast cancer diagnosis
Authors: Guo Ya , Zhang Heng , Yuan Leilei , Chen Weidong , Zhao Haibo , Yu Qing-Qing , Shi Wenjie
Published: April 2024

Breast cancer (BC) is the most prominent form of cancer among females all over the world. The current methods of BC detection include X-ray mammography, ultrasound, computed tomography, magnetic resonance imaging, positron emission tomography and breast thermographic techniques. More recently, machine learning (ML) tools have been increasingly employed in diagnostic medicine for its high efficiency in detection and intervention. The subsequent imaging features and mathematical analyses can then be used to generate ML models, which stratify, differentiate and detect benign and malignant breast lesions. Given its marked advantages, radiomics is a frequently used tool in recent research and clinics. Artificial neural networks and deep learning (DL) are novel forms of ML that evaluate data using computer simulation of the human brain. DL directly processes unstructured information, such as images, sounds and language, and performs precise clinical image stratification, medical record analyses and tumour diagnosis. Herein, this review thoroughly summarizes prior investigations on the application of medical images for the detection and intervention of BC using radiomics, namely DL and ML. The aim was to provide guidance to scientists regarding the use of artificial intelligence and ML in research and the clinic.
Are the ICHD-3 criteria for headache attributed to idiopathic intracranial hypertension valid? Headache phenotyping and field-testing in newly diagnosed idiopathic intracranial hypertension
Authors: Hansen Nadja Skadkær , Korsbæk Johanne Juhl , Yri Hanne Maria , Jensen Rigmor Højland , Beier Dagmar
Published: April 2024

Background

Headache burden is substantial in idiopathic intracranial hypertension. The classification of idiopathic intracranial hypertension headache by the International Classification of Headache Disorders (ICHD) is an important tool for research and clinical purposes.

Methods

We phenotyped headaches and tested sensitivity and specificity of the ICHD-3 criteria for idiopathic intracranial hypertension headache in a prospective cohort of patients suspected of idiopathic intracranial hypertension at two tertiary headache centers.

Results

Sensitivity was 93% and specificity was 100% of ICHD-3 criteria for idiopathic intracranial hypertension-related headache validated in idiopathic intracranial hypertension ( n = 140) and patients in whom idiopathic intracranial hypertension was suspected but disproven ( n = 103). The phenotype of new/worsened headaches related to idiopathic intracranial hypertension suspicion was equally migraine-like (p = 0.76) and tension-type-like (p = 0.08). Lumbar puncture opening pressure was higher ( p < 0.0001) and pulsatile tinnitus more frequent ( p < 0.0001) in idiopathic intracranial hypertension patients, but neither improved the applicability of the headache criteria, nor did papilledema.

Conclusion

Headache phenotype is not distinct in idiopathic intracranial hypertension. ICHD-3 criteria for idiopathic intracranial hypertension headache are sensitive and specific, but simplicity can be improved without compromising accuracy. We propose that a new or worsened headache temporally related to active idiopathic intracranial hypertension is a sufficient criterion for idiopathic intracranial hypertension headache regardless of headache phenotype or accompanying symptoms, and that elements of idiopathic intracranial hypertension diagnostics (papilledema and opening pressure) be segregated from headache criteria. Trial Registration: ClinicalTrials.gov Identifier: NCT04032379
Comprehensive analysis of bond stress transfer mechanisms in glass fiber-reinforced polymer-reinforced concrete beams using acoustic emission monitoring
Authors: Rather Amer Iliyas , Banerjee Sauvik , Laskar Arghadeep
Published: April 2024

The present study investigates the critical bond characteristics between glass fiber-reinforced polymer (GFRP) bars, which is essential for the application bars as corrosion-resistant components in structural concrete. The interfacial bond deterioration and stress transfer mechanisms have been investigated in the present study by employing acoustic emission (AE) monitoring in hinged-type GFRP-reinforced concrete (GFRP-RC) beam specimens. The bond strength of the test specimens, governed by chemical adhesion, mechanical interlocking, and frictional resistance, has been intricately examined. Various AE signal parameters as well as historic and severity indices derived from the AE signal parameters have been meticulously evaluated and correlated with bond stress and rebar slip variations. The present study has also introduced an innovative approach of using the sentry function for the assessment of bond deterioration and associated mechanisms. The results of the present study demonstrate the reliability of AE parameters in monitoring debonding and bond strength variation, the effectiveness of the sentry function in evaluating damage progression, and the utility of historic and severity indices in capturing micro-mechanism transformations. The accurate localization of debonding and the qualitative distribution of bond stress have also been demonstrated by through correlations between cumulative AE parameters and rebar slip, Additionally, the present study also highlights the significance of peak frequency variations in AE signals, serving as a crucial tool for quantifying the mechanical interlocking and interfacial friction. The results contribute significantly to precise assessments and development of effective strategies for mitigating bond deterioration in GFRP-RC elements.
Incidence of Breast Cancer in Younger Women: A Canadian Trend Analysis
Authors: Seely Jean M. , Ellison Larry F. , Billette Jean-Michel , Zhang Shary X. , Wilkinson Anna N.
Published: April 2024

Purpose: Breast cancer (BC) incidence is increasing globally. Age-specific BC incidence trend analyses are lacking for women under age 50 in Canada. In this study, we evaluate the incidence trends in breast cancer in women under age 50 in Canada and compare them with corresponding trends among women 50 to 54. Methods: BC case counts were obtained from the National Cancer Incidence Reporting System (1984-1991) and the Canadian Cancer Registry (1992-2019) both housed at Statistics Canada. Population data were also obtained from Statistics Canada. Annual female BC age-specific incidence rates from 1984 to 2019 were derived for the following age groups: 20 to 29, 30 to 39, 40 to 49, 40 to 44, 45 to 49, and 50 to 54. Changes in trends in age-specific BC incidence rates, if any, and annual percent changes (APCs) for each identified trend, were determined using JoinPoint. Results: Statistically significant increasing trends in BC incidence rates were noted for almost all age groups: since 2001 for 20 to 29 (APC = 3.06%, P < .001); since 2009 for 30 to 39 (APC = 1.25%, P = .007); since 1984 for both 40 to 49 (APC = 0.26%, P < .001) and 40 to 44 (APC = 0.19%, P = .011), increased since 2015 for 40 to 49 (APC = 0.77%, P = .047); and since 2005 for 50 to 54 (APC = 0.38%, P = .022). Among women 45 to 49 there was a non-significant increase since 2005 (APC = 0.24, P = .058). Statistically significant average annualized increases in BC incidence rates were observed for each age group studied. Conclusions: Examining age-specific incidence rates formed a more complete picture of BC time trends with significant increasing trends in the incidence of BC among women in their 20s, 30s, 40s, and early 50s. A greater awareness regarding the increasing number of cases of BC in women younger than 50 is critical to allow for earlier diagnosis with its resultant reduced mortality and morbidity.
Culturally Diverse Students’ Perspectives on Sexual Violence Policies: Recommendations for Culturally Sensitive Approaches to Prevention in Higher Education
Authors: Kennedy Karen Dolores , Malinen KelleyAnne , MacLeod Emily , VanTassel Brooke , O’Rourke Kristin , Small Legs-Nagge Caryn
Published: April 2024

Culturally sensitive approaches in sexual violence prevention (SVP) refer to the proactive measures and strategies designed to address unique cultural circumstances impacting SVP. It focuses on fostering a culture of consent, respect, and equity and creating a safe and supportive environment for all individuals regardless of your identity. Increasing cultural diversity on university campuses poses unique challenges in preventing sexual violence (SV). Cultural diversity brings different perspectives, norms, and values regarding sex, sexuality, and gender roles. It can contribute to varying understandings of consent, differing attitudes toward SV, and diverse victimization experiences. These differences can create barriers to effectively addressing and preventing SV. The multiphase Culture and Perspectives on Sexual Assault Policy study, conducted at four universities in Eastern Canada, employed a qualitative research design involving focus groups with culturally diverse student participants. The findings revealed a strong desire for more education on sex, sexuality, SVP, and the intersections of culture. Additionally, the findings emphasize the importance of education and comprehensive prevention efforts that consider cultural differences, challenge gender normativity, debunk rape myths, and address the shame and secrecy associated with experiencing SV. These insights have significant implications for promoting a sense of community ownership, increasing the effectiveness and sustainability of prevention efforts, and helping to create a campus environment where all students feel safe, supported, and valued.
The Relationship between Grandparents’ Violent Discipline and School Bullying Behavior among Left-behind Children
Authors: Dong Simeng , Dong Qinnan , Chen Min
Published: April 2024

Most left-behind children in rural China are raised by their grandparents, whose parenting style significantly impacts children’s development. This study examined the association between grandparents’ violent discipline and left-behind children’s school bullying. This cross-sectional study recruited a sample of 462 left-behind children aged 10 to 15 years old (Age Mean = 12.372, 49.351% girls) from four rural primary and junior high schools in Chongqing, China. There was a significant positive association between corporal punishment (β = .236, p < .001) and psychological aggression (β = .272, p < .001) of grandparents and children’s school bullying. Empathy and moral disengagement mediate the above association. Cross-gender comparisons indicated that corporal punishment had a greater positive relationship with school bullying in boys than girls (βgirls = .154, p < .01; βboys = .250, p < .001). At the same time, boys’ moral disengagement was also more likely to lead to school bullying (βgirls = .233, p < .001; βboys = .337, p < .001). We discuss the implications of these findings for preventing bullying in schools for children left behind.
Pornography Use and Sexual Coercion: Examining the Importance of Frequency, Type, and Other Factors
Authors: Marshall Ethan A.
Published: April 2024

Research on pornography use and sexual coercion has provided some evidence that there is an association between these two behaviors. One area in this body of research where there is a need for improvement is the operationalization of pornography use. In particular, a need for researchers to capture all relevant aspects of pornography use that are associated with sexual coercion. These aspects include frequency of use, type of pornography used, investment in use, sexual scripts adopted from pornography, compulsive use, and first exposure. The current study aims to examine which of these aspects of pornography use are significantly associated with sexual coercion. A sample of 365 college males was surveyed on their pornography use, engagement in sexually coercive behaviors, and other relevant variables. Results show that sexual scripts and investment in pornography use are significantly related to self-reported sexual coercion. These findings indicate that the frequency with which someone views pornography may not be driving the relationship between pornography use and sexual coercion and that an individual’s monetary investment in their pornography use habit, as well as their adoption of sexual scripts from pornography, may be what is driving this relationship. In addition, these findings have implications for the aspects of pornography use that researchers should focus on when examining the relationship between pornography use and sexual coercion.
Sex Differences in the Effects of Adverse Childhood Experiences on Institutional Misconduct among Adults in Prison
Authors: Clark Valerie A. , Duwe Grant
Published: April 2024

Research from the past few decades has highlighted the long- and wide-reaching effects of adverse childhood experiences (ACEs). These experiences can negatively affect mental and physical health, as well as behaviors and interpersonal relationships well into adulthood. While it is generally understood that ACEs are prevalent in correctional populations, no prior studies have measured this issue using a large representative and racially and ethnically diverse sample of both male and female adult correctional populations in the United States. The data used for this study were collected via an assessment administered to more than 2,100 adults in Minnesota’s prison system. Descriptive findings revealed that multiple and varied forms of ACEs were common in the histories of this state’s incarcerated population, particularly among females and incarcerated persons who identified as Black, White/non-Hispanic, and American Indian/Alaskan Native. The multivariate results revealed that past exposure to ACEs increased the likelihood and speed of disciplinary convictions after admission to prison for males, but not for females. Overall, the results underscored the importance of assessing for responsivity factors upon admission to prison, including ACEs.
Interacting Barriers: How Barriers Compound Across Levels of Analysis to Affect Teams
Authors: Ruge-Jones Luisa , Barley William C. , Wilson Sam R. , Poole Marshall Scott
Published: April 2024

Collaboration remains a central aspect of contemporary work and a source of emergent barriers that hinder team success. Scholarship has identified the breadth of barriers teams can face when working together and recognizes barriers as interdependent. This paper builds on this scholarship to address the types of relationships barriers can have as they interact across levels of analysis to affect teams. We draw on qualitative interview data with scientific teams to explore relationships among barriers stemming from teams’ internal processes and context. We identify common relationship patterns among barriers that can be used as a framework for analyzing complex, multi-level barrier systems affecting team outcomes. Our data highlight the importance of considering longitudinal, strategic support for targeting cross-barrier interactions when seeking to intervene in collaborations. This framework has practical application in supporting teams and creating policies that support collaborative work.
Regional Variation in Lifetime Probability of Admission to Residential Aged Care in Australia
Authors: Cooper-Stanbury Mark
Published: April 2024

Objectives

This paper aims to apply a novel demographic technique to update – and extend to sub-national regions – estimates of the lifetime probability of admission to residential aged care.

Methods

Making optimal use of Australian data sources on aged care usage, mortality and population, this study adopts a two-population life table approach to produce an updated set of national probability estimates and first-time regional estimates.

Results

The probability of admission generally increases with age: nationally, lifetime probability at age 65 is 50% for women and 37% for men, rising to 55% and 46%, respectively, at age 85. This general pattern varied somewhat across regions.

Discussion

The regional results point to inequities in the uptake of care, thereby informing providers, governments, aged care advocates and anyone interested in equity of access.
Comparative Life Cycle Assessment of a centrifugal compressor impeller: Hybrid technology production versus welding production
Authors: Giraldi Alessandro , Delogu Massimo , Del Pero Francesco , Verdi Angelica , Lombardozzi Luca
Published: April 2024

Sustainable development is one of the main objectives in the turbomachinery sector to achieve the climate neutrality targets set by 2050 protocols. The manufacturing industry consumes an average of 23% of global energy, significantly contributing to the generation of greenhouse gases and other pollutants. Therefore, it is crucial to research technological solutions aimed at reducing consumption for the benefit of the environmental sustainability of the products manufactured. This study presents a comparative environmental impact assessment using the Life Cycle Assessment (LCA) methodology to evaluate the sustainability of two technological alternatives used to produce centrifugal impellers in the industrial sector. The first process analyzed deals with making an impeller by welding the shroud to the impeller body. The second process involves producing the component from a semi-finished product, machined through milling and Electrical Discharge Machining (hybrid solution). The study has been conducted at Nuovo Pignone company. It is based on primary inventory data collected through specific measurement campaigns and modeled using the environmental database Ecoinvent v3.9. The results were produced using the ILCD Midpoint method, and four different impact categories were investigated: Climate Change, Human Toxicity, Cancer Effects, and Freshwater Ecotoxicity. The results demonstrate that the solution produced through hybrid manufacturing is generally less impactful compared to the welded one. The insight implemented in the work is functional in drafting suggestions for manufacturers and customers to reduce the environmental burdens of the examined product.
Baicalein exerts beneficial effects in lipopolysaccharide-induced pulmonary inflammation by modulating macrophage polarization and inhibiting pyroptosis
Authors: Kou Yile , Zhang Lu , Shi Zhaoling , Zhang Guocheng , Chang Jing , Bai Qian , Gao Na , Ding Hui
Published: April 2024

The disruption of the immune system by viral attack is a major influencing factor in the lethality of COVID-19. Baicalein is one of the key effective compounds against COVID-19. The molecular mechanisms regarding the anti-inflammatory properties of Baicalein are still unclear. In this study, we established LPS-induced mice to elucidate the role of Baicalein in the treatment of acute lung injury (ALI) and its potential molecular mechanisms. In vivo experiments showed that Baicalein could significantly ameliorate LPS-induced acute lung injury and reduce proteinous edema in lung tissue. In addition, Baicalein inhibited M1 macrophage polarization, promote M2 macrophage polarization, and regulate inflammatory responses. Furthermore, Baicalein could inhibit the expression of protein molecules associated with pyroptosis and mitigate the lung tissue injury. In summary, we revealed the therapeutic effects of Baicalein in acute lung injury, providing the theoretical basis for its clinical application.
Interested Gazes and Invisible Audiences: Judicial Narratives on Sex Work
Authors: Rai Stuti
Published: April 2024

The dominant paradigm in Indian legal review is doctrinal and empirical. However, judgements of the Supreme Court of India are often couched in rhetoric and literary sources. In this regard, the law and literature paradigm has created different interpretive tools, including law as literature and literature in law. These are the tools that I utilise to explore how sex work is understood and how the ideal sex worker is conceptualised by the judges of India. Judgements on sex work are particularly conducive to a law and literature analysis as in these cases, the courts are called upon to justify legal rationality, forcing them to draw upon popular morality, best reflected in persuasive literature. Judicial dicta in four cases that have come before the Supreme Court over the span of half a century (1964–2012) are analysed to provide a cultural critique of the post-colonial and neoliberal sensibilities that underlie judicial discourses.
Health Services Management: The Inclusive Sceneries of Higher Education Quality Enhancement Endeavours for the College of Medicine at Yarmouk University
Authors: Rawabdeh Ali A. A.
Published: April 2024

As individuals contrast in their views of higher education around the globe, universities confront numerous challenges to get and sustain credit for survival. Hence, progressing and improving the quality of education and learning has gotten to be a must to fulfil customer’s needs. The utmost point of this article is to provide guidelines for the foundation of quality enhancement strategies in Yarmouk colleges coupled with clarification of major quality criteria for accreditation. The researcher conducted many field visits with numerous interviews with key authorities and surveyed numerous log records with the webpages; utilised many distributed materials over quality assurance endeavours and made an initial evaluation of the current circumstance to examine the quality assurance and improvements. This article perceived 15 desired goals and objectives (issues/shortcomings) to the College of Medicine as guidance with confirmations; elective course of activities for development and enhancement of quality profile in Yarmouk University (YU); set up handfuls of priorities for improvements to realise the specified objectives to be executed; and furnished evaluation and monitoring criteria. YU staff are suggested to police and learn at that point declared emphatically the Western common convictions and characteristic ways of creating improving quality components. It is trusted that YU representatives will perceive the application of quality enhancement measures in this article as handy, and is severely required for their developments to achieve Yarmouk’s goals.
Caste of Marginality and Migration in Bihar
Authors: Kumar Arun , Shriyan Diksha
Published: April 2024

In the world of ‘global capital—peripheral labour’, multiple strategies are employed to accumulate labouring bodies to augment accumulation, the lifeline of capitalism. Relations of inequalities have historically helped capitalism to accumulate and thrive. Growth in India and its accompanied en masse informalisation of labour is located at the intersection of caste, gender and migration. Foregrounding the cultural political economy of agrarian poverty, migration and informalisation of labour, we underline the criticality of caste in reproducing a labour force that is perennially insecure, unsettled and unorganised. Based on a qualitative study in rural Araria, Bihar, we argue that informalisation of labour is institutionalisation of vulnerability, which is sustained and reproduced through caste-based social relations in. Due to the wages in kind, repressive tenancy system and low productivity, indebtedness remains an annual necessity for the lowered caste workers and tillers even when the lowered 1 castes move beyond the bounds of the village and into the wider informal economy, their lack of social capital and adverse incorporation in the urban labour market keep them off the benefits of migration and urban growth.
Development and Initial Validation of the Parenting Styles Circumplex Inventory (PSCI)
Authors: Meisel Samuel N. , Ramer Nolan E. , Hopwood Christopher J. , Colder Craig R.
Published: April 2024

Parenting style refers to the emotional climate in which parents nurture and guide their child’s social development. Despite the prominence of parenting style research, many studies still create their own psychometrically untested measures of parenting styles, use measures that do not capture the uninvolved parenting style, or use median splits to convert dimensional assessments into parenting style typologies. To address these measurement issues, the current studies developed the Parenting Styles Circumplex Inventory (PSCI) which is rooted in Contemporary Integrative Interpersonal Theory and provides a framework to unite typology and dimensional parenting style measurement approaches. The current article describes the development and initial validation of the PSCI across three samples of college students ( Ns = 571, 361, 385). The 32-item PSCI consists of eight octant scales which each assess unique combinations of parental responsiveness and demandingness. The measure asks respondents to answer each question about their mother- and/or father-figure. The circumplex structure of the PSCI was confirmed and replicated across studies and the PSCI demonstrated meaningful associations with indicators of parenting practices, relationship functioning, psychopathology symptoms, and substance use. Results from this study provide initial support for the PSCI as a path forward for measuring parenting styles.
Bioinformatic Analysis and Clinical Case Studies Identify CD276 as a Promising Diagnostic Biomarker for Clear Cell Renal Cell Carcinoma
Authors: Zhang Zhiyu , Xu Jianhao , Song Zhen , Zhang Jianglei , Lin Yuxin , Ouyang Jun
Published: April 2024

Objective

This study aimed to explore the relationship between CD276 and clear cell renal carcinoma (ccRCC) and assess the diagnostic value of CD276 in ccRCC.

Methods

Expression levels of CD276 in ccRCC and para-cancer tissues were compared and analyzed retrospectively using data obtained from TCGA and GEO databases. The clinical data was analyzed prospectively. Immunohistochemistry and RT-PCR analyses were used to analyze the expression of CD276 at the mRNA and protein levels. These analyses compared the expression between ccRCC tissues and para-cancer tissues obtained from 70 patients with ccRCC. Next, ELISA was used to analyze peripheral blood samples from 70 patients with ccRCC and 72 healthy individuals, facilitating the differentiation of ccRCC patients from normal controls. Finally, we utilized the Kaplan-Meier method to generate ROC curves for assessing the diagnostic value of CD276 for ccRCC.

Results

Analysis of TCGA and GEO data revealed that the mRNA expression of CD276 was higher in ccRCC tissues than in para-cancer tissues ( P < .05). Clinical validation using IHC and RT-PCR confirmed that the expression of CD276 was higher in ccRCC tissues than in para-cancer tissues, both at the mRNA and protein levels ( P < .05). ELISA demonstrated that the expression of CD276 was higher in ccRCC patients than in normal individuals, and patients with a higher pathological grade showed higher expression of CD276 in the peripheral blood than those with a lower pathological grade ( P < .05). ROC curves drawn from the above three datasets demonstrated that CD276 had a high diagnostic value for ccRCC (AUC = .894, .795, .938, respectively).

Conclusion

The expression of CD276 was higher in ccRCC tissues and positively associated with the pathological grade. Therefore, CD276 may serve as a molecular biomarker for ccRCC prediction.
Year in Review 2023: Noteworthy Literature in Cardiothoracic Critical Care
Authors: Alber Sarah , Tanabe Kenji , Hennigan Andrew , Tregear Hans , Gilliland Samuel
Published: April 2024

This article reviews noteworthy investigations and society recommendations published in 2023 relevant to the care of critically ill cardiothoracic surgical patients. We reviewed 3,214 articles to identify 18 publications that add to the existing literature across a variety of topics including resuscitation, nutrition, antibiotic management, extracorporeal membrane oxygenation (ECMO), neurologic care following cardiac arrest, coagulopathy and transfusion, steroids in pulmonary infections, and updated guidelines in the management of acute respiratory distress syndrome (ARDS).
Hotel Performance in the Guangdong-Hong Kong-Macau Greater Bay Area: A Non-Homogeneous Perspective
Authors: Tsai Henry , Gao Chenchen , Liu Hongwei
Published: April 2024

Improving upon previous studies on hotel performance evaluation in terms of efficiency, which usually treat different hotels as homogeneous in their product provision, this study examines the performance of 53 hotels in the Guangdong-Hong Kong-Macau Greater Bay Area (GBA) during 2015 to 2019, by employing data envelopment analysis with a non-homogeneous decision making units (DMUs) model. The results show that the hotels in GBA were inefficient, and those with high product diversification are generally closer to achieving optimal efficiency levels, particularly those providing rooms, food and beverage, meeting services, and spa services, while those providing only rooms had the worst performance. Among the GBA cities included in this study, the non-homogeneous efficiency scores of the hotels in Guangzhou outperformed those of hotels in the other cities, and the overall hotel efficiency score of the core cities was better than that of the key node cities.
Are dental care records in childhood associated with financial hardship in adulthood?
Authors: Hiilamo Aapo , Keski-Säntti Markus , Mannevaara Matias , Kallio Jouko , Harjunmaa Ulla , Koskenvuo Karoliina
Published: April 2024

Introduction:

Previous studies show that dental health is associated with educational and labour market outcomes, but it is unclear whether dental care records in childhood can serve as early markers of financial hardship risk in adulthood.

Methods:

Data on sociodemographic variables and dental records of all children born in Finland and who lived their childhood in the city of Espoo were obtained from national registers ( n=1867). Debt defaults at the age of 23 years were used as a measure of adulthood financial hardship. Caries recorded in dental check-ups and unnotified absence from dental appointments in childhood were derived from electronic health systems. Logistic regression models were fitted to investigate the extent to which these variables were associated with financial hardship in adulthood before and after adjusting for parental social assistance use.

Results:

The odds of adulthood debt defaults were higher for people with caries before the age of 13 years (odds ratio 1.37, compared with people without) and for people with significant caries multiple times (odds ratio 2.07). Unnotified absences from dental checks were strongly associated with debt defaults. These associations were substantially reduced after adjusting the models for parental social assistance use.

Conclusions:

The association between childhood dental care records and adulthood financial hardship mainly reflects the fact that parental socioeconomic status links to dental records. Nevertheless, data from dental care could be used in targeting appropriate measures to prevent financial hardship later in life.
Financial inclusion and the contested infrastructures of cash transfer payments in South Africa
Authors: Webb Christopher , Vanqa Mgijima Nandi
Published: April 2024

Across much of the South, digital technologies are increasingly central to the expansion of state social protection systems. Supported by major development agencies, many of these distributive technologies are developed and implemented by financial technology companies with the specific aim of accelerating financial inclusion. While researchers have documented the influence of these financial actors and logics over social policy, we know less about how these interventions are transforming the experience of receiving social protection. Based on qualitative and observational research with social grant recipients in South Africa, this research demonstrates how digital and financial technologies produce confusion, informational opacities and new forms of exclusion among grant recipients. It suggests that the increasingly prominent role of financial technologies in the delivery of social protection undermines state capacity and further entrenches the influence of neoliberal logics over social policy. Finally, the article suggests that these technologies may be transforming the nature of social citizenship in South Africa, undermining efforts to advance universal and redistributive social protection policies.
Robot-Assisted MIDCAB Using Bilateral Internal Thoracic Artery: A Propensity Score–Matched Study With OPCAB Patients
Authors: Algoet Michiel , Verbelen Tom , Jacobs Steven , De Praetere Herbert , Marynissen Michiel , Oosterlinck Wouter
Published: April 2024

Objective:

Robot-assisted minimally invasive direct coronary artery bypass (RA-MIDCAB) is an attractive strategy for coronary revascularization. Growing evidence supports the use of total arterial grafting in coronary surgery. We evaluated total arterial left-sided coronary revascularization with bilateral internal thoracic artery (BITA) using RA-MIDCAB and compared it with a propensity score–matched (PSM) off-pump CAB (OPCAB) surgery population.

Methods:

We retrospectively included all isolated OPCAB and RA-MIDCAB surgery using BITA without saphenous vein graft from January 1, 2015, to October 31, 2022. We analyzed all our RA-MIDCAB patients and performed PSM to compare them with our OPCAB population. Primary outcomes were major adverse cardiovascular and cerebrovascular events (MACCE) and mortality. Secondary outcomes were surgical parameters, length of hospital stay, and learning curve.

Results:

We included 601 OPCAB and 77 RA-MIDCAB procedures, which resulted in 2 cohorts of 54 patients after PSM. Mortality and MACCE survival analysis showed no significant difference. There was less blood transfusion in the RA-MIDCAB (16.7%) compared with the OPCAB group (38.9%; P = 0.02). We observed fewer intensive care unit (ICU) admissions (24.1% vs 96.6%), shorter ICU stay (0.78 ± 1.7 vs 1.91 ± 1.01 days), and shorter hospital stay (6.78 ± 2.4 vs 8.01 ± 2.5 days) in the RA-MIDCAB versus OPCAB group ( P < 0.01). Surgery time decreased from 400.0 ± 70.8 to 325.0 ± 38.0 min with more experience in RA-MIDCAB BITA harvesting ( P < 0.01).

Conclusions:

This is a first publication of 77 consecutive RA-MIDCAB BITA harvesting for left coronary artery system revascularization. This technique is safe in terms of MACCE and mortality. Additional advantages are shorter length of hospital stay, fewer ICU admissions, and less blood transfusion.