bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparative Analysis of Classical Test Theory and Item Response Theory using Chemistry Test Data
Authors:   Graduate Studenta & Lecturerb, aUniversiti Sultan Zainal Abidin, Kuala Terengganu, Malaysia. & bFaculty of Education, Yusuf Maitama Sule University, Kano, Bichi Ado Abdu , Embong Rahimah ,   Assoc. Professor, Department of Education, Dakwah and Islamic Civilization, Faculty of Contemporary Islamic Studies, Universiti Sultan Zainal Abidin, Kuala Terengganu, Malaysia., Talib Rohaya ,   Senior Lecturer, School of Education, Universiti Teknologi, Malaysia, Johor Bahru, Malaysia., Salleh Sakinah ,   Senior Lecturer, Faculty of Human Sciences, Universiti Pendidikan Sultan Idris, Malaysia
Published: July 2023

Assessment of learning involves deciding whether or not the content and objectives of education are down pat by administering quality tests. This study assesses the standard of Chemistry action take a look at and compares the item statistics generated mistreatment CTT and IRT strategies. A descriptive survey was adopted involving a sample of N=530 students. The specialised XCALIBRE 4 and ITEMAN 4 softwares were used to conduct the item analysis. Results indicate that, both the two methods commonly identified 13(32.5%) items as “problematic” and 27(67.5%) were “good”. Similarly, a significantly higher correlation exists between item statistics derived from the CTT and IRT models, [(r=-0.985,) and (r=0.801) p<0.05] for item difficulty and discrimination respectively; the study concludes that the Chemistry Achievement test used do not pass through the processes of standardisation. Secondly, CTT and IRT frameworks appeared to be effective and reliable in assessing test items as the two frameworks provide similar and comparable results. The study recommends that the teacher made Chemistry tests used in measuring students’ achievement should be made to pass through all the processes of standardisation. Meanwhile, CTT and IRT approaches of item analysis ought to be integrated within the aspects of item development and analysis because of their superiority within the investigation of reliability and minimising measurement errors.
ROLE OF UTERINE ARTERY DOPPLER SCREENING IN PREDICTING HYPERTENSIVE DISORDERS OF PREGNANCY
Authors: Lamba Pulkita , Bedi Mini , Kaur Amanpreet , Kaur Harbhajan , Kaur Manjot
Published: July 2023

Introduction- Hypertensive disorders of pregnancy are one of the most prevalent obstetrics complications with unknown etiology. Inspitе of all thе mеdical advancеmеnt, hypertensive disorders of pregnancy rеmains onе of thе most common causеs of maternal and pеrinatal morbidity and mortality. So, thеrе is a fеlt nееd for idеntifying a non-invasivе highly sеnsitivе and spеcic mеthod for еarly diagnosis and trеatmеnt of hypertensive disorders of pregnancy. Uterine artery Doppler is a non invasive method used to assess earlier changes in uteroplacental circulation.It is reliable, safe, easily reproducible tool and also can be performed along with nuchal transulency scan. Material and methodsAftеr following strict inclusion and еxclusion critеria 250 patiеnts wеrе rеcruitеd in thе study and wеrе subjеctеd to transabdominal
ultrasound after taking proper history and blood pressure recorded at each antenatal visit. Mean of uterine artery PI taken In 1st and 2nd trimester amd patients were followed till term to note the development of HDP and neonatal outcome. Results- The sensitivity, specicity, PPV , NPV of 1st trimester uterine artery Doppler was 6%, 97%, 33.3%, 80.5%:while that of 2nd trimester was 32%, 90%, 44.4%, 84.1% Conclusion- Hence,the specicity is very high, hence, it is concluded that women with normal Doppler are unlikely to develop hypertensive disorders of pregnancy.
INTRAOPERATIVE FROZEN SECTIONS - AN AUDIT STUDY
Authors: Sweety V Shinde , Manisha B Dhanve
Published: July 2023

Context: Audit aims to verify conformance to quality work and assesses practical implementation. Aims: To evaluate pre-analytic and analytic phases of frozen sections (FS)at a tertiary healthcare centre. Setting & Design: Observational ambispective study over six months. Preanalytical phase (clinical Materials & Methods: information and grossing adequacy) and analytical phase (turnaround time TAT and section quality) were assessed. Results: Total 56 cases of FS noted. TAT for FS diagnoses was 26.5+8.7 minutes. TAT between FS and nal report was 3.7 + 2.4 days. Discordance between FS and nal report was noted in 8(14.3%) cases. Quality results w Conclusions: ere achieved as per international norms despite limited resources. Remedial actions by teamwork can assist to improve quality output.
A CLINICAL STUDY AND MANAGEMENT OF VARICOSE VEINS IN THE LOWER LIMB
Authors: Garg Chinky , Singh Nargesh Shailendra
Published: July 2023

Aim & Objectives - Varicose veins of lower limb is a common clinical manifestation, which starts early in the life but assumes an innocent course for variable length of time. This study intends to know the distribution, clinical features, pathophysiology and the various modalities of investigations and overall management of varicose veins of lower limbs effectively and to prevent its complications. Methods- A total of 40 study subjects were selected from patients admitted to JA hospital from a period of 12 month (June 2022 to May 2023). Detailed study of the cases were done including history record of general systemic examination, investigation, treatment and follow up of patients. Results- In this study male are more prone to development of varicosity of lower limb than the female (M: F= 4.71:1) the disease is more common in 30 to 40 year age groups. Occupation involving prolonged standing and family history are the main contributory factors, patients present with engorged vein (92.5%) and pain (50%) as main symptom. the surgical procedure of SSFL combined with stripping of the long saphenous vein and sapheno-popliteal ligation was performed in 22.5% of the cases. Seroma was the most frequently occurring complication observed in 10% of the cases. Conclusion- This study shows the varicose veins of lower limbs is more common in middle age group with male predominance, occupation and family history are the other contributory factors, doppler ultra sound scanning is the investigation of choice.
A CASE SERIES OF GASTROINTESTINAL STROMAL TUMOUR AND ITS VARIOUS PRESENTATION WITH MANAGEMENT
Authors: Thirunavukkarasu S. , Santhi B. , Vinoth Kumar P. , Ramprasath A.
Published: July 2023

Gastrointestinal stromal tumor (GISTs) are rare mesenchymal neoplasms of the alimentary tract accounts for 0.1 -3% . GISTs arise from interstitial cells of cajal and most commonly occurs in stomach. They are best identied by computed tomography (CT) scan and most stain positive for CD117 (C-Kit), CD34, and/or DOG-1. Aim And Objective: The aim of the case series to analyze epidemiological aspects, clinical presentation , challenges in diagnosis , management of the diseases. A case series of 3 patients with GIST admitt Materials And Methods; ed in the DEPARTMENT OF GENERAL SURGERY IN GOVERNMENT KILPAUK MEDICAL COLLEGE AND GOVERNMENT ROYAPETTAH HOSPITAL ,CHENNAI .All 3 cases have been analyzed in this study period and followed up until discharged from the hospital Results: Out of three patient one patient landed up in emergency ward with obstructive features and intervened by emergency procedure, second patient presented with unusual presentation and treated by surgery with chemotherapy , and other patient presented with symptoms and treated by surgery and followed by chemotherapy. GISTs are r Conclusion: elatively rare tumor of gastrointestinal tract. Hence a higher degree of suspicion is essential for identifying GISTs clinically. Earlier identication will help in better management. This case series shows 3 possible clinical presentations of GIST.
MOHS SURGERY: NARRATIVE REVIEW
Authors: Maritza Castanõ Liberato Lisbed
Published: July 2023

Technique widely used in dermatology for the treatment of skin cancer. The historical perspective highlights the evolution of Mohs surgery since its development by Dr. Frederic Mohs in the 1930s, emphasizing its focus on basal cell carcinoma and subsequent renements in instrumentation, anesthesia, and tissue processing methods. Mohs surgery, which involves stepwise removal of cancerous tissue layers with immediate microscopic examination to ensure complete tumor removal while preserving healthy tissue. The advantages of Mohs surgery include high cure rates, tissue preservation, real-time margin assessment, and precise mapping. However, the procedure is time-consuming, requires specialized training, and may have higher costs compared to alternative treatments. Perioperative management considerations, including preoperative assessment, anesthesia techniques, surgical procedure, wound care, and follow-up, are discussed to ensure optimal outcomes and patient satisfaction. Understanding the historical context, surgical technique, advantages, and disadvantages of Mohs surgery is crucial for healthcare professionals involved in the management of skin cancer patients.
A COMPARATIVE ANALYSIS ON FINANCIAL PERFORMANCE OF INFOSYS LTD. USING RATIO ANALYSIS AND TREND ANALYSIS: AN EMPIRICAL STUDY
Authors: Subba Jerika , Das Raj
Published: July 2023

The main focus of this research paper is to make a comparative analysis of one of the leading IT Company by market capitalization named Infosys Ltd. The nancial status of this company has been analyzed by leveraging out various nancial ratios such as liquidity, protability, solvency and activity ratios. For the purpose of conducting our research, the data has been collected from secondary sources such as company's annual reports, journals, etc. The study covers a time period from FY18 to FY22. Sampling technique adopted for the purpose of carrying out this research is purposive sampling method. We also used trend analysis to forecast the future growth in sales and protability of the business. This research also uses simple correlation technique to compute the relationship between liquidity and protability of the company. More interestingly, this paper also considers the outputs of regression analysis so as to nd the cause - and - effect relationship among variables.
TO STUDY THE EFFECT OF MYCOBACTERIUM TUBERCULOSIS INFECTION AND ANTI TUBERCULOSIS TREATMENT ON SERUM MAGNESIUM LEVEL AT IRD, SMS MEDICAL COLLEGE, JAIPUR
Authors: Kumar Saini Yogesh , Bhandari Chand , Kumar Saini Bhupendra , Saini Manoj
Published: July 2023

Background: Malnutrition and tuberculosis are both problems of considerable magnitude in most of the underdeveloped regions of the world. Magnesium ion concentration of blood is inversely proportional to the type and extent of the disease which could possibly be due to chronic malnutrition and the amount and destruction of lung tissue in cases of pulmonary tuberculosis. This study is to see the effect of mycobacterium tuberculosis infection and antituberculosis treatment on serum magnesium level. Material & Methods: A hospital based longitudinal case control study done on all outdoor and indoor diagnosed patients of Pulmonary Tuberculosis (PTB), Multidrug-resistant Pulmonary Tuberculosis (MDRPTB) and healthy controls in IRD, Jaipur. 56 diagnosed cases of pulmonary tuberculosis before starting treatment (group PTB at initial) were followed after 2 months of treatment (group PTB at the end of intensive phage). 56 diagnosed case of multi drug resistant pulmonary tuberculosis (group MDRPTB). 56 age and sex matched healthy controls were taken and every candidate was examined for serum magnesium. Results: Our study showed that the maximum numbers of patients (54.76%) were in the age group of 31-50 years, male preponderance (57.14%). It was observed that Mg++ levels were signicantly decreases in PTB and MDRPTB cases as compared to control group. The Mg++ levels were also found to be signicantly lower in MDRPTB patients as compared to PTB patients (p=0.0047*). The mean value of serum magnesium level was signicantly lower in malnourished patients (1.575±0.012 mg/dl) compare to normal BMI patients (1.585±0.011 mg/dl), (p-value<0.001*) and was statistically signicant at initial in PTB group. The comparison of type of lesion & severity of disease with serum magnesium level was statistically signicant at initial and at the end of intensive phase in PTB group. Conclusion: We concluded that decreased serum magnesium is a constant nding during pulmonary tuberculosis. In order to better understand the role of magnesium in pulmonary tuberculosis further clinical studies are required. Randomized controlled trials are warranted to generate higher levels of evidences to support our ndings.
PREVALENCE OF ASYMPTOMATIC BACTERIURIA AMONG PREGNANT WOMEN
Authors: Kaur Gill Gurkiran , Gupta Abha , Rani Sharma Raj , Agarwal Surya , Patel Akshika
Published: July 2023

Introduction: Urinary tract infection is a common bacterial infection in women because of the short urethra which can easily be contaminated with microorganisms from the gastrointestinal tract. Pregnant women are at an increased risk of urinary tract infection because of anatomic and physiological changes of pregnancy that gives a conducive environment for bacterial proliferation. Asymptomatic bacteriuria (ASB) is dened as a signicant count of bacteria (>105 colony forming units (CFU)/mL) in the urine plus absence of clinical signs or symptoms. Early screening and treating promptly of ASB during pregnancy can prevent further complication of bacteriuria in pregnant women. Aim And Objectives: To study the prevalence of asymptomatic bacteriuria in all pregnant women attending OBGY OPD or getting admitted in IPD at Pacic Medical College & Hospital, Udaipur. Primary: To nd the prevalence of asymptomatic bacteriuria in all pregnant women attending OBGY OPD or getting admitted in IPD. Material And Methods: A Prospective Cross Sectional Observational Analytical study conducted on 100 pregnant women attending the OPD clinics or IPD from February 2021- January 2022 at department of Obstetrics and Gynecology of Pacic medical college hospital. Results: The prevalence of asymptomatic bacteriuria was signicantly (p=0.001) associated with UTI and anemia as past history. The prevalence of asymptomatic bacteriuria was found to be 15%. Conclusion: 1. The prevalence of asymptomatic bacteriuria was found to be 15%. 2. IUCD past history was in 35% and anemia was in 26% patients. However, Catheterization and UTI was in 23% and 21% patients respectively. 3. The prevalence of asymptomatic bacteriuria was highest in age >30 years (21.4%) and was least in 26-30 (8%) years. However, there was no signicant (p>0.05) association prevalence of asymptomatic bacteriuria with age. 4. The prevalence of asymptomatic bacteriuria was signicantly (p=0.001) associated with UTI and anemia as past history.
LEBER'S HEREDITARY OPTIC NEUROPATHY IN AN OLD MAN: A CASE REPORT
Authors: Pusapati Lakshmi Chaitanya Varma Maj , Padma V
Published: July 2023

Leber's hereditary optic neuropathy (LHON) is a rare mitochondrial disorder characterized by bilateral optic nerve atrophy leading to acute or subacute painless central vision loss. This case report describes a rare occurrence of LHON in a 71-year-old man, highlighting the clinical and genetic heterogeneity of the disease. The patient initially experienced visual loss in the left eye, which progressed rapidly, followed by deterioration of vision in the right eye six weeks later. Genetic testing revealed the pathologic mtDNA 14,484 point mutation, which is responsible for a signicant proportion of LHON cases. Environmental factors such as alcohol and smoking, along with genetic mutations, contribute to the optic nerve degeneration seen in LHON. The diagnosis of LHON can be challenging due to its variable presentation, but early recognition and appropriate management are crucial. Although no specic treatment for LHON currently exists, supportive care is provided, and alternative therapies like idebenone/vitamin B/vitamin C combination therapy show some promise. Increased awareness and understanding of LHON will lead to improved outcomes and potential developments in effective treatments for this devastating condition.
CONTRIBUTION OF MANUSCRIPT “YOGADIPIKA” IN MANAGEMENT OF JWARA DISEASES
Authors: G. Somani Sonal , R. Joshi Mohan
Published: July 2023

In treating disease, diagnosis and formulations are important to know. MSS “Yogadipika” deals with
important featured of diseases and treatment. First disease explained by author is fever (Jwara). Aim:-
This study is done to know contribution of MSS in management of fever (Jwara). Material & Methods: - Manuscript was collected
from Govt. Mss Lib, Bhandarker O. R. Institute, Pune (India) in Pune. Comprehensive reading and comparison of the Manuscript
of each sutra has been done. Observation: - on studying MSS different interesting information, observations found related to 37
disease & Nadipariksha. Discussion: - Jwara is rst disease explained in MSS in origin, cause, types, pathogenesis, symptoms,
and treatment etc. is studied in detail. Conclusion: - on comparison with Bhrut-trayee and Laghu-trayee, some symptoms & 43
new formulations with different conditions in fever are given by author.
Characteristics of Nonylphenol and Octylphenol Discharge from Wastewater Treatment Facilities in Southern Gyeonggi-do
Authors: Seo Soo-Jung , Choi Phil-Kwon , Nam Woo-Kyung , Hwang Seon-Min , Lee Jin-Young , Jung Seon-Hee , Park Seo-Gyeong
Published: July 2023

This study aimed to evaluate the discharge characteristics of nonylphenol (NP) and octylphenol (OP) in the effluent of wastewater treatment facilities in the southern Gyeonggi-do. The detection rates of NP and OP were found to be 39.3% and 43.1%, respectively, with median values ranging from 1 to 3 μg/L across all industries. The industries that showed a detection rate of 50% or more were car wash, chemical experiment, fabric leather, paper wood, and plating facilities, with rates ranging from 50% to 75%, while other industries had detection rates of 21.7% to 36.8%. In terms of facility size, small-size establishments such as Type 4 and Type 5 showed higher detection rates in the "Na" region where somewhat relaxed standards are applied on a regional basis. This is because the proportion of Type 4 and Type 5 industries, including various concentration distributions of chemical experiments, research facilities, car washes, petrochemical, and plating industries, is higher than 77.7% overall and concentrated at a rate of 55.6% or higher in the “Na” region. Furthermore, the correlation coefficient (R) between NP and OP exhibited moderate association with values of 0.45 and 0.60 for car washes and plating industries, respectively. Chemical experiments, paper and wood, electrical and electronic, and medicine and hospital facilities showed strong association with correlation coefficients of 0.83, 0.82, 0.82, and 0.79, respectively. The findings in this study can be expected to serve as fundamental data for NP and OP in the establishment of water quality pollutants designation and discharge standards (draft) currently being pursued.
A Comparative Study on the Evaluation of BOD Analysis Methods
Authors: Kim Ah-Hyen , Yu Bong-Gwan , Kang Dae-Shin , Kim Ji-Hyeon , Kang Jeong-Won , Yoon Sung-Hee , Choi Soo-Mi
Published: July 2023

In this study, data for increasing the efficiency of researcher manpower and establishing the validity of the electrode method are presented via a comparative evaluation of the titrimetric and electrode methods for BOD analysis. When comparing the analysis results of the titrimetric and electrode methods for wastewater, sewage, and leachate, no difference was observed between two methods. Therefore, if the electrode method is used instead of the titrimetric method, the amount of reagents for BOD analysis can be effectively reduced, resulting in a decreaded workloads for analysts as well as the hazards and risks posed to them, ultimately. In addition, the amount of acid wastes generated due to the use of sulfuric acid can be reduced, thereby reducing costs, which is economically beneficial.
Hiperglicemia intrahospitalaria en pacientes con COVID-19 sin diagnóstico previo de diabetes
Authors: Berganza Sagastume Axel Rubén
Published: July 2023

PROBLEMA: La hiperglicemia intrahospitalaria es una de las complicaciones más comunes en COVID-19. Se define como cualquier persona que durante la admisión o en cualquier momento de su hospitalización presenta una concentración de glucosa sérica mayor o igual a 140 mg/dl. OBJETIVO: Describir la hiperglicemia intrahospitalaria en pacientes con COVID-19 sin diagnóstico previo de diabetes. MÉTODO: Se realizó una revisión bibliográfica basada en fuentes primarias y secundarias, tipo monografía de compilación. RESULTADOS: La hiperglicemia intrahospitalaria en pacientes con COVID-19 sin diagnóstico previo de diabetes se describe como una complicación común que aparece en 90-93% de los pacientes que presentan valores de glucosa sérica elevada durante su hospitalización. CONCLUSIÓN: Los principales mecanismos fisiopatológicos son la disfunción pancreática aguda producida por el virus del SARS-Cov2, el estrés metabólico y el uso de glucocorticoides. El tratamiento inicia con análogos de insulina rápida en glicemias mayores a 180 mg/dl, luego con inhibidores de la dipeptidil peptidasa 4 al haber glucosa mayor de 140 mg/dl por más de 48 horas y se combina insulina basal si la glucosa permanece mayor a 180 mg/dl por más de 48 horas.
Factores de riesgo materno-fetales que se presentan en hemorragia posparto temprana
Authors: Alegría Barrow Eileen Mariemilia
Published: July 2023

PROBLEMA: La hemorragia posparto se describe como la pérdida de cualquier cantidad de sangre que cause signos de hipovolemia o inestabilidad hemodinámica en la paciente. Esta se encuentra entre las primeras tres causas de mortalidad materna y su prevalencia es mayor en los países del tercer mundo. OBJETIVO: Describir los factores de riesgo materno-fetales que se presentan en hemorragia posparto temprana. MÉTODO: Se realizó un estudio monográfico de compilación, de carácter documental basado en una revisión bibliográfica y en la síntesis de la evidencia expuesta por investigadores que han abordado la temática de factores de riesgo materno-fetales que se presentan en hemorragia posparto temprana y antecedentes ginecobstétricos. RESULTADOS: Los factores sociodemográficos ligados a hemorragia posparto temprana consisten en tener entre 10 y 19 años o mayor a 35 años, ser analfabeta o bajo nivel de escolaridad, vivir en áreas rurales o con poca accesibilidad y no tener compañero fijo o estar legalmente casada. En Guatemala, los departamentos de San Marcos, Huehuetenango, Quiché y Alta Verapaz han tenido las mayores tasas de morbilidad materna por hemorragia posparto con un estimado de 4 de cada 10 muertes maternas. CONCLUSIÓN: Los factores de riesgo materno-fetales que se presentan en hemorragia posparto temprana son atonía uterina, macrosomía fetal, miomatosis uterina, alta paridad, desgarros y laceraciones, retención de restos placentarios, polihidramnios, descenso de la cabeza fetal, sepsis y gesta múltiple.
Satisfacción del usuario en el puesto de salud de Shororaguá, Chiquimula
Authors: García Rodríguez Gabriela Rocío
Published: July 2023

PROBLEMA: la satisfacción en los usuarios, es un indicador suficiente para evaluar la calidad de los servicios que prestan las instituciones relacionadas con salud y que usan como estrategia para la transformación y mejora de los sistemas sanitarios modernos. OBJETIVO: determinar el nivel de satisfacción como indicador de calidad de los servicios prestados por el puesto de salud de Shororaguá, Chiquimula. MÉTODO: se realizó un cuestionario basado en el modelo de Avedis Donabedian a 200 usuarios que asisten a consulta durante un período de dos meses. RESULTADOS: los aspectos que conforman la dimensión de proceso, en los cuales se identificó un porcentaje significativo de satisfacción, se relacionan con la atención médica en general: amabilidad, evaluación detallada, explicación adecuada sobre el diagnóstico y tratamiento. CONCLUSIÓN: se percibe a nivel global que el grado de satisfacción de los usuarios no es bueno, ya que no se cumple con las expectativas de los mismos en un 90%, respecto a estructura física, comodidad, recursos materiales, cantidad de personal, horario de atención, tiempo de espera, acceso al medicamento, capacidad para resolver sus necesidades y la satisfacción como tal, la cual deben percibir al menos en un 95% según los estándares internacionales de calidad.
Knowledge, Attitudes and Practices of Mothers regarding the Nutrition of Children from 6 to 59 Months in the Urban Commune of Koniakary (MALI)
Authors: Niare Boubacar , Keita Chaka , Coulibaly Mamadou B , Keita Mamadou , Diarra Samou , Ba Kadiatou , Toure Sidi , Coulibaly Ouazoum , Traore Abdramane , Diallo Oumar , Traore Momine , Sangho Hamadoun , Dembe Mamadou
Published: July 2023

Introduction: Nutrition is a health package, which is defined as the body's processing and use of food. The primary pathological situation resulting from the quality of nutrition is malnutrition. Objective: To describe the knowledge, attitudes and practices (KAP) related to the practices of mothers on the nutrition of children aged 6-59 months and to bring about a change in behaviour among the target group in the urban commune of Koniakary. The Methodology: This was a prospective and descriptive action research study in the urban commune of Koniakary, involving 99 mothers or babysitters and their children aged 6 to 59 months. The action research is carried out in three phases: survey, action and evaluation. Our work focused on the evaluation after the actions. Results: In our study, the age range of 15-20 years was predominant among the mothers and childminders (28%), 57.6% were married and monogamous and 92% were housewives. The children were predominantly male (52%). The 6-10 month age group was the most represented, 29.3%. The vast majority of children were vaccinated 94%. In relation to the knowledge and attitudes of mothers and guardians: The importance of supplementary feeding for children increased from 59.2% to 92.9%. Concerning practices: exclusive breastfeeding up to 6 months increased from 50% to 80.8%, hand washing with soap increased from 62.6% to 96%, the use of the health centre in case of illness as a first intention was 65.7%, this rate increased to 91.9%.
Spectrophotometric Method for Determination of Oseltamivir in Capsule Dosage Form
Authors: Chaganti Soujanya , Vangala Sree Vibha , Naraparaju Swathi , Anumolu Pani Kumar Durga , Barla Karuna Devi
Published: July 2023

Objectives: Study was aimed to establish and vindicate a simple, accurate and precise spectrophotometric method for the quantification of oseltamivir in API and capsule dosage form. Materials and Methods: The green coloured chromogen complex absorbance which was formed by the oxidative coupling with loss of two electrons and a proton of oseltamivir with MBTH in presence of FeCl3 was measured at 640nm. The amount of oseltamivir labelled in the marketed formulation (Fluvir) was determined without any interference owed with excipients. Results: A correlation coefficient of 0.999 was observed within the concentration range of 10-110μg/mL. The method was aided by various validation parameters such as LOD, LOQ and percentage relative standard deviation values (3.75 μg/mL, 9.86 μg/mL and 0.999 respectively). The percentage assay in capsule dosage form was found to be 97.6, which in conformance with ICH guidelines. Conclusion: Results were found to be within the permissible limits. Present method was verified statistically in consonance with ICH Q2R (1) guidelines. Based on above remarks, developed method may be successfully employed in regular analysis of oseltamivir in various pharmaceutical dosage forms.
Amniotic Membrane Transplant: About A Case in Mali
Authors: Kadiatou BA , Moro Sidibe , Aichata Tall , Bakary Danfaga , Fatoumata Sidibe , Aly Konipo , Brainima Coulibaly , Assiatou Simaga , Oumar Diallo , Seydou Diallo , Sadio Cissoko , Adama Dembele , Kadiatou Berthe , Daouda Goita , Sekou Malle , Fantamady Tounkara Cheick , Abdoulaye Napo , Seydou Bakayoko , Fatoumata Sylla
Published: July 2023

The amniotic membrane graft consists of suturing a fragment of membrane on the de-epithelialized area with a few separate stitches. We report a case of amniotic membrane transplant on keratitis following the local use of a traditional treatment in Mali. It was of a case of amniotic membrane transplant performed in Mali in the management of bilateral keratitis occurring following eyewash with a decoction made from cooked tamarind leaf in a 36-year-old man. We used a 3cm/3cm square AMTRIX® Amniotic Membrane from the Banque de Tissus de France. The membrane was grafted in Patch on the two eyes of our patient, this allowed us to have good healing and improved visual acuity. The use of the amniotic membrane in the management of keratitis gives good functional and anatomical results. She is now possible, However, its availability and cost remains a challenge for our developing countries.
Isolated Aplasia of the Lateral Semicircular Canal without Hearing Loss: A Case Report
Authors: Azzahiri I. , Kirami S. , Benzalim M. , Alj S.
Published: July 2023

We present a case of a 25-year-old woman with isolated aplasia of the lateral semicircular canal (LSCC), a rare congenital malformation that results in the absence or underdevelopment of the LSCC. The patient had vertigo, left-sided tinnitus, and persistent chronic headaches but no hearing loss. High-resolution computed tomography (CT) and magnetic resonance imaging (MRI) were used to detect the malformation and associated vasculo-neural conflict. The aplasia of the LSCC was the only abnormality observed. The article explains the embryology of inner ear development and associated anomalies. CT and MRI were found to be effective imaging techniques for detecting ear malformations. The article also explains the importance of proper diagnosis and assessment of hearing loss for patients with this malformation.
Subcutaneous Phaeohyphomycosis – A Rare Case Report
Authors: Desai Pranav , Patel Gargi , Patel Arpita , Patel Riddhi , Shah Manali
Published: July 2023

Phaeohyphomycosis is a heterogenous group of fungal infection caused by a variety of naturally pigmented fungi. A 56year old male presented with painless subcutaneous swelling over left anterior aspect of distal leg since 1 year. Local examination revealed a painless, fluctuant, soft, mobile swelling measuring 3x2 cm in size over left anterior aspect of distal leg. Microscopic examination revealed granulomatous inflammation with presence of septate fungal hyphae with constriction and occasional irregular branching. (Identical to Phaeohyphomycosis).
Myasthenia on a Case at Sikasso Hospital
Authors: Dembélé Adama , Sidibe Moro , Poma Hachimi Amadou , Malle Sékou , Traore Moumine , Napo Abdoulaye , Diallo Oumar , Goita Daouda , Dembele Djonny Jonas , Nomoko Cheick , Diarra Karim , Togo Mamadou Adama , Kadiato Kadiato
Published: July 2023

Myasthenia gravis is aautoimmune disease which is due to a defect in the transmission of signals between the nerves and the muscles. Each year, there are 2 to 5 new cases per million people. We report the case of a young 35-year-old male patient seen in ophthalmology at the Sikasso hospital for ptosis and loss of visual acuity. The ptosis was improved after putting ice on the eyelids for 2 min (Ice cube test). The immunological assay for anti-MUSK (MUSK-Ab ELISA, IBL) and anti-RACH antibodies was performed. Chest CT did not detect thymus hyperplasia or thymoma, with no abnormalities of the pericardium and diaphragm. We observed an improvement in the signs after 6 months of treatment.
A Colic Adenocarcinoma as the Primary Cause of Colo-Colic Intussusception: A Rare Case of Obstruction
Authors: Azzahiri I. , Biadi M. , Slioui B. , Hamoune N. , Mouhsine A. , Atmane M. , Rhanmi A. , Jouabri B. , Lahkim M. , Elkahder A. , Barni R. El
Published: July 2023

This article discusses the case of a 70-year-old woman who presented with abdominal pain and vomiting, and was diagnosed with colonic-colonic intussusception caused by a tumor. Colonic intussusception is a rare cause of acute abdomen in adults, and malignant tumors are the most frequent cause of colonic intussusception. The article highlights the importance of imaging, specifically abdominal CT scans, in diagnosing and managing this condition. The CT scan can confirm the site of intussusception and specify the severity signs, and it is more specific than ultrasound and endoscopy. The article also describes the different intussusception patterns seen on CT scans and their significance. Early diagnosis is important in preventing complications such as infarction and perforation. The authors suggest that colonic intussusception may be the result of infiltration of the colonic wall musculature by the malignant tumor despite the colon being devoid of peristaltic activity. Overall, the article emphasizes the importance of a combination of clinical and radiologic data in diagnosing and managing colonic intussusception caused by tumors.
Jejunal GIST: An Uncommon Presentation of Obscure GI Bleeding
Authors: Ghosh Chanchal Kumar , Rahman Md. Ashiqur , Tabassum Nowrin , Dey Sumon
Published: July 2023

Introduction: Only 0.1-3 percent of all GI malignancies are gastrointestinal stromal tumors, which are the most frequent mesenchymal tumors of the digestive system. Gastrointestinal bleeding, either acute or chronic, is the most typical GIST manifestation. Case Presentation: We describe the case of a 32-year-old man who experienced repeated bouts of melena and hematochezia over the course of four months, necessitating multiple blood transfusions and causing a weight loss of 5 kg. Fresh and clotted blood was seen during a colonoscopy using a 50 cm ileoscopy; however there were no obvious lesions. A wide-based submucosal edema with surface ulceration was discovered by deep enteroscopy via the oral route at 150 cm from the incisor teeth. After the patient had a laparoscopic excision, the diagnosis of a GIST coming from the jejunum was confirmed by histological and immunohistochemistry tests. Conclusion: The diagnosis of bleeding GISTs in the proximal small intestine is challenging due to the inaccessibility of these areas with conventional endoscopes. In such cases, capsule endoscopy or deep enteroscopy plays a valuable role in diagnosis. The primary treatment strategy for jejunal GIST is complete surgical resection.
Unexpected CT Scan Discovery of a Giant Galen Vein Aneurysm in An Infant: A Rare Case Report
Authors: O Benfaddoul , A El Moutaalik-billah , A El Hajjami , B Boutakioute , M Ouali , N Gannouni Idrissi
Published: July 2023

Aneurysmal malformation of the Galen vein is an uncommon abnormality, comprising less than 1% of all congenital cerebral vascular malformations. However, it accounts for approximately 30% of such malformations in the pediatric population. This condition represents a cerebral arteriovenous malformation that develops prenatally, initiating prior to ten weeks of gestation. It arises from the formation of arteriovenous fistulas connecting the choroidal circulation and the median prosencephalic vein, an embryonic precursor of the Galen vein, which subsequently undergoes dilation. Here, we present an exceptional case of this malformation that was incidentally detected during a Brain CT scan.
Waardenburg Syndrome Anesthetic Management: Two Cases Experiences
Authors: Boubekri Ayoub , W Atmani , M Meziane , A Bouaiyda , M Ababou , H Brarou , M Balouki , A Jaafari , A Bait , M Bensghir
Published: July 2023

This article presents the anesthetic management of two cases of Waardenburg syndrome (WS) in patients undergoing cochlear implantation. Mutations in genes that control the neural crest cell migration and division during the embryonic period are the hallmark of the hereditary disorder known as WS. White forelock, bright blue eyes, heterochromia from iris coloring deficiency, unusual facial deformities, and sensorineural deafness are the key phenotypic characteristics of WS. The anesthetic management of patients with WS poses challenges due to their multisystem abnormalities.
CONFIGURATION OF CONTENT MATERIALS ON REGIONAL REGULATIONS ON REGIONAL RESEARCH
Authors: Wijaya Rudi , Raharjo Eko , Septiana Rika
Published: July 2023

The strengthening of the national research system after the promulgation of Law Number 11 of 2019 concerning the National System of Science and Technology (UU Sisnas Science and Technology) requires that the research and innovation system be strengthened in the regions. Legal instruments in the form of regional regulations have an urgency to ensure the sustainability of the research and innovation ecosystem and are also strengthened in the regions. Therefore, the content of regional regulations on research needs to be well formulated so that the content material is not only a copy of the National Science and Technology Law but can adapt to regional conditions, needs, and ongoing conditions.
ELECTION OF REGIONAL HEAD BASED ON HIERARCHY: STRENGTHENING ARGUMENTATION OF THE DISCUSSION OF ABOLISHING DIRECT ELECTIONS IN INDONESIA AND PROPOSED MODELS
Authors: Hidayat Taufik , Fitrianingrum Lia
Published: July 2023

Since the direct election of regional heads (Pilkadasung) has resulted in six major problems. These six big problems gave birth to the discourse of eliminating the Pilkadasung in Indonesia, and replacing it with a new system that is still within the corridors of democracy. The formulation of the problem in this paper are: (1) what arguments can be given in order to strengthen the discourse on the abolition of the Pilkadasung?, and (2) the proposed model that can be given as a substitute for the abolition of the Pilkadasung?. This paper is a conceptual study. Based on state administration practices that occur in the Special Region of Yogyakarta, where the election of regional heads uses the determination method, where Sri Sultan Hamengkubuwono and Sri Paku Alam are appointed by the President as Governor and Deputy Governor (DIY). As well as. practice of state administration in the Special Capital Region of Jakarta, where the Mayor is appointed by the Governor. Then, based on the theory from Manor and Crook. Strengthening the argument that the Pilkadasung is not the only way that is the most democratic, so alternative models can be used with other systems. In an effort to eliminate the six major problems of the Pilkadasung, the proposed model proposed in this paper is a hierarchy-based regional head election. The Governor is appointed by the President, and the Mayor/Regent is appointed by the Governor. The appointment process uses the following mechanisms: (1) an open position auction, (2) a public hearing, and (3) a fit and proper test at the Provincial DPRD for the Governor and at the City/Regency DPRD for the Mayor and/Regent. This mechanism is implemented gradually and transparently.
ON THE EFFECTIVENESS OF THE PERIODEZATION OF MEMBERS OF THE PEOPLE’S REPRESENTATIVE COUNCIL IN TERMS OF JURIDICAL
Authors: Setiawan Agus , Khoiriah Siti , Perbawati Chandra
Published: July 2023

Indonesian Legislative Assembly is the high institutions and public representatives with the authority to design, discuss and establish a law that the state requires. As in Article 7 Verse (4) Act number 13 in 2019 on MD3 that the term of parliament was five (5) years and ended when new members of the parliament were taking an oath. There is a legal vacuum to the effectiveness of the legislative regulatory management, which needs to be examined for whether or not there is a fight on the principle of certainty of law and democracy. To find answers to questions of formulated problems treated using normative law research with a descriptive approach with secondary data. The result of this study has been decided that the effectiveness of the regional autonomy and policy on micro finance as well as law.
DIVINE VALUE OF INDONESIAN JURISPRUDENCE: A REFLECTION OF PANCASILA JURISPRUDENCE
Authors: Firmansyah Ade Arif , Evendia Malicia
Published: July 2023

This paper aims to examine divine values as a form of reflection on Pancasila values in Indonesian jurisprudence. This study is important considering that the current conditions for the establishment and enforcement of Indonesian law tend to pay little heed to divine values. Using the doctrinal writing method with a conceptual approach it is found that:Jurisprudence which believes in God is a form of reflection of Pancasila values and is part of Pancasila jurisprudence. Jurisprudence which believes in God is closely related to religious principles which in essence want humans to remain in their minds and consciences in living life. The essence of theology in theology of law focuses on strengthening aspects of morality with regard to the immunity of the legal structure, the establishment of legal substance and legal culture
LEGALITY OF TERMINATION OF CONSTITUTIONAL JUDGES BY THE COUNCIL OF REPRESENTATIVES BEFORE THEIR TERMS OF OFFICE END
Authors: Sari A.P Aulia Oktarizka Vivi Puspita , Satria Indah
Published: July 2023

Constitutional judges must have integrity and personality that is beyond reproach, be fair, be a statesman who masters the constitution and state administration, and not concurrently serve as a state official. Dismissal of constitutional judges before the end of their term of office can only be carried out for reasons, namely resigning at their own request submitted to the chairman of the Constitutional Court, being physically or mentally ill continuously for 3 (three) months so that they cannot carry out their duties as evidenced by a doctor's certificate , as well as dishonorably dismissed for reasons as set out in Article 23 paragraph (2) of the Constitutional Court Law. Related to the legality of dismissal of Constitutional Justices by the House of Representatives before the term of office ends. This type of research is normative legal research or normative juridical. A dishonorable dismissal of a Constitutional Judge can only be carried out if the reasons for dismissal are met in accordance with the provisions in Article 23 paragraph (2) of the Constitutional Court Law. Whereas the House of Representatives is only capable of nominating candidates for Constitutional Justices through an application to the President at the request of the Chief Justice of the Constitutional Court which will then be determined based on a Presidential Decree. After the Constitutional Court accepts the Presidential Decree, the Presidential Decree will be notified to the institution authorized to apply for a replacement of Constitutional Judges
VERIFICATION OF POLITICAL PARTIES PARTICIPATING IN GENERAL ELECTIONS BEFORE AND AFTER THE DECISIONS OF THE CONSTITUTIONAL COURT
Authors: Kharismawan Yusuf Mulya
Published: July 2023

Political parties are the political superstructure of a democratic country, namely as a means for citizens to occupy political positions through general elections. The requirements for passing verification as election participants by the General Elections Commission must be met by political parties contained in the election law, by making it harder for political parties to pass verification as well as exceptions for several political parties that have met certain verification requirements so that they are immediately designated as participants to next elections. The exception is not in accordance with Article 27 paragraph (1), Article 28D paragraph (1) and Article 28D paragraph (3) of the 1945 Constitution as unconstitutional through several decisions of the Constitutional Court. The purpose of this study is to determine the conditions for passing the verification of political parties participating in the General Election before and after the Constitutional Court Decision, and analyze the considerations of the Constitutional Court judges regarding the requirements to pass the verification of political parties participating in the General Election based on the principle of equal treatment before the law, using a normative approach. It can be concluded that the considerations of the Constitutional Court regarding the verification requirements of political parties participating in the general election are inconsistent because the material test of the 1945 Constitution used are different and there is not required for the Constitutional Court to use jurisprudence as a basis for consideration even though there are similarities in substance.
REFORMULATION OF STATE PROPERTIES AS A GUIDELINE FOR THE DIRECTION OF INDONESIA'S NATIONAL DEVELOPMENT
Authors: Anggoro Firna Novi
Published: July 2023

Discourse of reviving the direction of the country is still ongoing as an effort to correct the national development planning system that is currently used. The pros and cons of coloring efforts to revive the direction of the country. The revival of the direction of the state is considered a manifestation of the return of the authoritarian system of authoritarianism in the new order era. On the contrary, the positive response to reviving PPHN is able to ensure that national development is more thorough, directed, integrated, sustainable and accountable. The problem is how the urgency of forming PPHN as a guideline for the direction of national development in the future? This research is normative juridical research using a statutory approach (statute approach) and a conceptual approach (conceptual approach). The national development system based on the SPPN Law has various weaknesses. this system is still executive heavy and vulnerable to abuser practices has various weaknesses. this system is still executive heavy and vulnerable to abuse of power. In addition, the current national development system provides a gap between the pattern of government development at the central, provincial, district/city levels plus between the leadership before and after it so as to create development that is directed, sustainable and more accountable. It is necessary to reformulate the PPHN which is regulated in the 1945 Constitution of the Republic of Indonesia and subsequently implemented in the system of administering state government power in Indonesia. The granting of constitutional authority to the MPR in the formation and determination of the PPHN will provide a unified perception considering that all colors of political parties take a common consensus for the interests of the nation and state. The implementation of development will be accountable to the MPR in the form of a performance report, even though the president is no longer the mandate of the MPR. This accountability is an effort to revive the principle of checks and balances on the implementation of national development.
LESÕES CERVICAIS NÃO CARIOSAS – ETIOLOGIA, PREVALÊNCIA, ASPECTOS CLÍNICOS E DIAGNÓSTICOS: REVISÃO SISTEMATIZADA
Authors: Gomes Soares Pires Lílian , Santos Silva Edilyane kese , Santos de Miranda Larissa Gabrielle , Pires Ary Oliveira , Pires Isabela Soares , Pires Arthur Soares
Published: July 2023

O presente estudo visa esclarecer a etiologia, prevalência, aspectos clínicos e diagnósticos das lesões cervicais não cariosas. Foram utilizadas bases de dados Lilacs, PubMed e Scielo, com os seguintes descritores: dental, lcnc e biocorrosão. Entre os critérios de inclusão, foram selecionados artigos publicados entre os anos de 2012 e 2022, nos idiomas inglês e português, onde foram incluídos 14 artigos. Os trabalhos mostraram que a maioria dos autores concordaram que os pré-molares superiores são os elementos dentários mais atingidos por esse tipo de lesão, seja por desgaste mecânico ou ácido, além do sexo feminino ser mais prevalente na doença. Outrora alguns mecanismos causam degradação molecular e consequentemente desgaste dentário por erosão como refluxo gastresofágico e/ou dieta acida. Outro evento contribuinte para problemática é a força de energia liberada que se propaga nos tecidos dentário como tensão, apertamentos e trincas. De acordo com os resultados encontrados, conclui-se que, as lesões cervicais não cariosas (LCNCs) possuem diferentes formas de apresentação e diferentes fatores etiológicos, tornando-se uma doença multifatorial. Consequentemente torna-se necessário estudar tais eventos, a fim de buscar aperfeiçoamento sobre o tema e, assim, auxiliar os cirurgiões-dentistas no diagnóstico e manejo do tratamento.
বাংলাদেশ পল্লী উন্নয়নের জন্য বিকেন্দ্রীকরণ
Authors: খান ডঃ আকবর আলী
Published: July 2023

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