bluuebunny/crossref_metadata_2025 huggingface dataset:
Personalized Medicine: Advanced Treatment Strategies to Revolutionize
Healthcare
Authors: Malviya Rishabha , Singh Arun Kumar , Verma Swati
Published: November 2022

Personalized medicine (PM) is about developing an individualized approach to each
patient's illness. Understanding how a patient's genomic portfolio renders them prone to various
diseases may be enhanced by discovering genetic, epigenetic, and medical evidence. Medical
therapy that is safe and effective for specific individuals may be predicted using the PM approach,
which is a complete expansion of an older methodology (One-Size-Fits-All). Patient’s well-being
and longevity may improve and costs are reduced if PM is used. Using existing biomarkers and
early genome and epigenomic processes to better understand PM may lead to earlier diagnosis of
the disease, including carcinogenesis. A key focus of the PM technique is preventative medicine,
which emphasizes proactive actions rather than depending only on reactive ones. More intrusive
procedures may be avoided or postponed using this technique, resulting in a higher quality of life
and lower financial burdens for patients. End-of-life care costs are putting a strain on governmentfunded healthcare systems across the globe, notably in the United States. When used in
conjunction with present treatments, PM may help them work better and lessen the disadvantages
of just non-PM methods. Using genetic profiling, doctors may choose a drug based on a
participant's genetic profile that minimizes unwanted side effects and ensures a better result while
also being less costly than a 'trial-and-error' approach to sickness treatment. The less effective nonPM ('trial-and-error') strategy leads to drug toxicity, severe adverse effects, reactive treatment, and
misdiagnosis. PM and proactive therapeutic regimens should be used more often to save costs and
enhance overall well-being.
Exploring Spousal Relationships Post-Stroke and the Association Between Relationship Congruence and Dysphagia-Related Caregiver Burden
Authors: Horyacheva Angela , Shune Samantha , Namasivayam-MacDonald Ashwini
Published: November 2022

Stroke survivors often receive spousal support for post-stroke impairments. The quality of spousal caregiving and couples’ wellbeing can suffer from post-stroke relationship changes and caregiver burden. Because swallowing impairment (dysphagia) is common post-stroke and spouses providing dysphagia care may experience burden, it is also important to explore whether relationship changes post-stroke are associated with dysphagia outcomes. The purpose of this study was to describe stroke survivor-spouse relationships post-stroke and explore whether relationship congruence is associated with dysphagia-related caregiver burden or swallowing-related quality of life (SWAL-QoL). Twenty-nine survivor-spouse couples completed a relationship questionnaire with 13 Likert scale questions (15 for spouses), analyzed for frequency of agreement and disagreement, and 2 open-ended questions regarding relationship strengths and possible improvements, analyzed thematically. Correlations were analyzed between relationship congruence (the absolute magnitude of difference between total scores of corresponding couples) and dysphagia-related caregiver burden score and SWAL-QoL using Spearman’s correlations. The majority (≥70%) of survivors and spouses responded positively to questions regarding closeness, care/affection, and communication in their relationship. Similarly, affection (41% survivors, 31% spouses) and communication (14% survivors, 17% spouses) were the first and second most described relationship strengths; spouses also identified honesty as the third most common strength (14%). Many participants were unsure of how the relationship could be improved (34% survivors, 31% spouses). Relationship congruence was not significantly correlated with dysphagia-related caregiver burden (rs = -0.273, p = 0.076) or SWAL-QoL (rs = -0.133, p = 0.246). Future research should assess how dysphagia affects relationships. This could provide further nuance regarding the association between spousal relationships and dysphagia outcomes and potentially inform future interventions.
The Changes That Occur in the Immune System During Immune Activation in Patients With Prediabetes From All Ethnicities, Aged 25-45 Years: Protocol for a Systematic Review and Meta-analysis (Preprint)
Authors: Mzimela Nomusa Christina , Sosibo Aubrey Mbulelo , Ngubane Phikelelani Siphosethu , Khathi Andile
Published: November 2022

BACKGROUND

Prediabetes is an asymptomatic, intermediate state between normoglycemia and the onset of type 2 diabetes mellitus. Recent reports indicate that during prediabetes, there are subclinical changes to immune cells and inflammatory markers. Therefore, this systematic review will provide a synthesis of the available data on the changes in the concentration of immune cells and selective inflammatory markers. It will also give evidence of a demographic impact on changes or complications in the prediabetes state.

OBJECTIVE

The objectives of this study are to create a protocol that will be used to analyze the collected data of previously published research based on immune cells such as neutrophils, lymphocytes, monocytes, eosinophils, and basophils, as well as inflammatory markers such as C-reactive protein, tumor necrosis factor-alpha, interleukin-6, P-selectin, cluster of differentiation 40 ligand, and fibrinogen. Additionally, an impact of demographics will be determined using the previously published data collected.

METHODS

This protocol was prepared through adhering to the PRISMA (Preferred Reporting Items for Systemic Reviews and Meta-Analysis) 2015 guidelines for reporting protocols. Published clinical studies that involve observational (cross-sectional, comparative cross-sectional, case-control, or cohort) study designs that include normal or nondiabetic and prediabetes reports will be used in this systematic review and meta-analysis. This will be accomplished by using clinical Medical Subject Headings to search on MEDLINE, Cochrane library, and African Journal Online. Reviewers (NCM, AMS, and AK) will screen all the results and select the studies that meet the eligibility criteria. Downs and Black Checklist will be used to check the risk of bias, and then a Review Manager v5.4 forest plot will be used for meta-analysis. Additionally, the forest plot will also be used for sensitivity analysis. The strength of evidence will then be assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach.

RESULTS

Since July 5, 2020, there are no participants recruited. Publicly available data will be used in the review and will be collected after this protocol publication. No ethics approval is required as no subjects will be used, and analysis will be based on reported data. Authors will be contacted if there was a misunderstanding related to reading their reported data.

CONCLUSIONS

The findings will clarify changes that might be observed in a study of interest based in the eThekwini district in South Africa.

CLINICALTRIAL

International Prospective Registry of Systematic Reviews (PROSPERO) CRD42020184828; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=184828

INTERNATIONAL REGISTERED REPORT

PRR1-10.2196/31619
Prevalence rates of tuberculosis, HIV, hepatitis B and C among migrant workers in Jordan (Preprint)
Authors: Khader Yousef , Warrad Nathirah , Maiteh Sudi
Published: November 2022

BACKGROUND

Background: Migration across national borders is an influential factor of consideration in the control of infectious diseases. Therefore, including migrants in surveillance and screening programs as well as linkage to care is mandatory to meet the public health targets of countries and regions.

OBJECTIVE

This study aimed to determine the prevalence of tuberculosis, HIV, HBV, and HCV among migrant workers applying for work permits in Jordan. The findings of this study are expected to guide health policy to prevent the spread of infectious diseases in Jordan.

METHODS

During the period 2018-2020, 439,622 migrant workers underwent routine testing for tuberculosis, HIV, and hepatitis B and C. Demographic, laboratory, and clinical data for those migrants were retrieved from the Directorate of Chest Diseases and Immigrants Health records. The overall prevalence of the mentioned diseases as well as by subgroups was calculated

RESULTS

The prevalence rates of TB and HIV among migrants were 54 per 100,000 migrants (11 per 100,000 male migrants and 138 per 100,000 female migrants, p<0.001) and 21 per 100,000 (11 per 100,000 male migrants and 41 per 100,000 female migrants, p<0.001), respectively. The prevalence of hepatitis B was 10 per 1000 migrants (12 per 1000 male migrants and 7 per 1000 female migrants, p<0.001) and the prevalence of hepatitis C was 37 per 1000 (51 per 1000 male migrants and 10 per 1000 female migrants, p<0.001) The prevalence of all studied conditions varied significantly according to gender, age, occupation, and country of origin.

CONCLUSIONS

The prevalence rates of TB, HIV, HBV, and HCV were generally higher among migrants than Jordanians. Evidence based health policies need to be drafted that aim to address migrant workers healthcare in order to ensure the lowest possible risk from infectious diseases to the people of Jordan is maintained.
Blended Care in Patients With Knee and Hip Osteoarthritis in Physical Therapy: Delphi Study on Needs and Preconditions (Preprint)
Authors: Weber Franziska , Kloek Corelien , Arntz Angela , Grüneberg Christian , Veenhof Cindy
Published: November 2022

BACKGROUND

Osteoarthritis is a major public health concern. Despite existing evidence-based treatment options, the health care situation remains unsatisfactory. Digital care options, especially when combined with in-person sessions, seem to be promising.

OBJECTIVE

The aim of this study was to investigate the needs, preconditions, barriers, and facilitators of blended physical therapy for osteoarthritis.

METHODS

This Delphi study consisted of interviews, an online questionnaire, and focus groups. Participants were physical therapists, patients with hip and/or knee osteoarthritis with or without experience in digital care, and stakeholders of the health care system. In the first phase, interviews were conducted with patients and physical therapists. The interview guide was based on the Consolidated Framework For Implementation Research. The interviews focused on experiences with digital and blended care. Furthermore, needs, facilitators, and barriers were discussed. In the second phase, an online questionnaire and focus groups served the process to confirm the needs and collect preconditions. The online questionnaire contained statements drawn by the results of the interviews. Patients and physical therapists were invited to complete the questionnaire and participate in one of the three focus groups including (1) patients; (2) physical therapists; and (3) a patient, a physical therapist, and stakeholders from the health care system. The focus groups were used to determine concordance with the results of the interviews and the online questionnaire.

RESULTS

Nine physical therapists, seven patients, and six stakeholders confirmed that an increase of acceptance of the digital care part by physical therapists and patients is crucial. One of the most frequently mentioned facilitators was conducting regular in-person sessions. Physical therapists and patients concluded that blended physical therapy must be tailored to the patients’ needs. Participants of the last focus group stated that the reimbursement of blended physical therapy needs to be clarified.

CONCLUSIONS

Most importantly, it is necessary to strengthen the acceptance of patients and physical therapists toward digital care. Overall, for development and usage purposes, it is crucial to take the needs and preconditions into account.

CLINICALTRIAL

German Clinical Trials Register DRKS00023386; https://drks.de/search/en/trial/DRKS00023386
A Comparison of Women’s and Men’s Web-Based Information-Seeking Behaviors About Gender-Related Health Information: Web-Based Survey Study of a Stratified German Sample (Preprint)
Authors: Link Elena , Baumann Eva
Published: November 2022

BACKGROUND

Gender-sensitive approaches to health communication aim to integrate gender perspectives at all levels of communication, as an individual’s biological sex and socially assigned gender identity have an impact on whether and how one acquires what type of health information. Due to the fast and low-cost opportunity to search for a wide range of information, the internet seems to be a particularly suitable place for gender-related health information about diseases of sex-specific organs and diseases where biological differences are associated with different health risks.

OBJECTIVE

This study aims to inform gender-related information provision and acquisition in 2 ways. The first objective was to provide a theory-driven analysis of web-based health information–seeking behavior (HISB) regarding gender-related issues. Therefore, the Planned Risk Information Seeking Model (PRISM), which is one of the most integrative models of HISB, was adapted and applied. Second, we asked for gender-specific motivational determinants of gender-related web-based HISB comparing the predictors in the groups of women and men.

METHODS

Data from a stratified web-based survey of the German population (N=3000) explained gender-related web-based HISB and influencing patterns comparing women and men. The applicability of PRISM to gender-related web-based HISB was tested using structural equation modeling and a multigroup comparison.

RESULTS

The results revealed PRISM as an effective framework for explaining gender-related web-based HISB. The model accounted for 28.8% of the variance in gender-related web-based HISB. Gender-related subjective norms provided the most crucial explanatory power, followed by perceived seeking control. The multigroup comparison revealed differences in the model’s explanatory power and the relevance of predictors of gender-related web-based HISB. The share of explained variances of web-based HISB is higher in men than in women. For men, norms were a more relevant promoting factor, whereas web-based HISB of women was more strongly associated with perceived seeking control.

CONCLUSIONS

The results are crucial for gender-sensitive targeting strategies and suggest gender-related health information interventions that address gender-related subjective norms. Furthermore, programs (eg, web-based learning units) should be developed and offered to improve individuals’ (perceived) abilities to perform web-based searches for health information, as those with higher control beliefs are more likely to access web-based information.
Examining Women’s Roles in the Publication of Medical Texts During The Sixteenth and Seventeenth Centuries
Authors: Johnston Katrina
Published: November 2022

Many obstacles prevented women from fully participating in medical professions throughout Early Modern England. Women could not learn about medicine at formal institutes, including Oxford and Cambridge, since contemporary scholars believed that women were incapable of the abstract thinking necessary to practice the science. Throughout the sixteenth and seventeenth centuries, the Royal College of Physicians prosecuted female medical practitioners for what they deemed to be unsanctioned activity in the medical field. Writing and publishing medical texts was also a difficult profession for women to pursue. Although women’s ability to produce documents of this nature improved for a time as a consequence of the decrease in print censorship following the English Civil War (1642-1651), male-authored books published on the subject continued to question their knowledge publicly.

Despite these numerous obstacles, females did participate in medical publications. Women evaded the Royal College of Physicians’ sanctions and participated in the world of medical publications through disclosing their treatments to male-physician authors, publishing almanacs, and using metaphors to conceal the medical advice in their texts. In three sections, this article highlights various ways women were involved in the publication of medical texts. The first component will examine the gender dynamics of medical publishing, focusing on how male authors utilized women’s knowledge to help sell their own texts. The second two sections examine how women were involved in medical literature in their own right and the strategies they employed to participate in medicine while simultaneously avoiding public scrutiny.
Preface to Special Issue "Fundamental and Applied Aspects of Geology, Geophysics and Geoecology"
Authors: Kuizheva S. , Bedanokov M. , Lebedev S.
Published: November 2022

This article is devoted to a special issue of the Russian Journal of Geosciences, which is dedicated to the VI International Scientific and Practical Conference "Fundamental and Applied Aspects of geology, geophysics and geoecology using modern information technologies" 2021 at Maikop State Technological University (Maikop, Republic of Adygea) consisting of "The Year of Science and Technology in Russia". The scientific forum is traditionally held once a two years and is of great interest to scientific community.
Estimation of Air Pollution Tolerance Index of Plants Across the Industrial Zone in Kanpur City, Uttar Pradesh
Authors: Yadav Anupam
Published: November 2022

One of the world's most serious issues today is air pollution caused by vehicle emissions, which poses a serious threat to both the environment and the health of living things (plants, humans, animals, microorganisms). The most severely impacted plants arVe those growing along side roadsides because they are the ones most frequently exposed to various air pollutants and exhibit a range of tolerance and sensitivity. In light of this, the current study's foundation was an evaluation of seasonal variation in the air pollution tolerance index (APTI). One of the most important sources of air pollution is vehicle emissions. The 11th most highly populated city in India is Kanpur. The parameter used to evaluate the sensitivity and tolerance level of plants based on Air Pollution Tolerance Index (APTI). This study aims to calculate the resistance and sensitivity of various plant species to air pollution. In the majority of developing countries, one of the causes of air pollution is vehicular emissions. Planting along the side of the road is a significant method of reducing the pollution that cars emit. The plants' APTI value is calculated using the pH, relative water content (RWC), total chlorophyll (Tch), and ascorbic acid (Asc) content of the leaves. The leaves of plants were collected from industrial zones Northen railway colony.Based on APTI values, In the industrial area, the most tolerant plant Ficus benghalensis (38.40) and Azadirachta indica (31.16), while lowest APTI value plants species Alstonia scholoaris( 9.5) and Adina cordifolia (11.6.0) in the industrial zone.
Monitoring and automation of the sewage system in the city of Maceió
Authors: Almeida V. C. V. , Batista T. C. M. , Lima F. N. , Melo L.T. , Silva E. C. M.
Published: November 2022

Flooding in urban basins is due, mainly, to excessive soil subdivision with the consequent sealing of surfaces, the occupation of riparian areas, inadequate drainage works and the obstruction of channels by debris and sediments. Considering the concepts of sustainability of urban drainage, the approach to solutions must consider a good characterization of the region, relating the occurrence of events with their causes and analyzing the effects in the regions of occurrence. One of the ways to obtain such answers is the characterization of problems related to flooding through interviews with the population that occupies affected areas. Aiming at the problem, this work deals with the assumption and practice of a flood risk supervision system, enabling its consistency with sensor networks to assist risk analysts in identifying and warning of the possibility of flooding, triggering the notification service through mobile devices of the interested community. It seeks to minimize, mainly, the social and financial losses caused by floods by predicting the flooding of coastal areas. The proposal of this work is to present a monitoring control of the garbage accumulated in manholes and its automatic removal in the city of Maceió.
Codiskcyclic sets of operators on complex topological vector spaces
Authors: Amouch Mohamed , Benchiheb Otmane
Published: November 2022

Let X be a complex topological vector space and L(X) the set of all continuous linear operators on X. In this paper, we extend the notion of the codiskcyclicity of a single operator T ∈ L(X) to a set of operators Γ ⊂ L(X). We prove some results for codiskcyclic sets of operators and we establish a codiskcyclicity criterion. As an application, we study the codiskcyclicity of C0-semigroups of operators.
Identification of viral RNA sequences in vampire bats (Desmodus rotundus) from central Mexico
Authors: Espinoza-Gómez Aldo , Moreno-Santillán Diana D. , Juárez-Maldonado Rafael , Gutiérrez Edgar G. , Salazar Ma. Isabel , Alonso-Palomares Luis A. , López-Vidal Juan Carlos , Elizalde-Arellano Cinthia , Ortega Jorge
Published: November 2022

Bats are important reservoirs of viral entities that cause diverse economical and health problems in several sectors. The purpose of this study was to determine the prevalence of the rabies virus in vampire bats. We also tested for 3 other zoonotic viruses in the collected tissue. We captured 45 vampire bats (Desmodus rotundus), which were measured and  sexed under standard parameters. We followed an RT-PCR reaction to amplify the viral products of four virus types: chikungunya (CHIKV), dengue (DENV), rabies (RABV) and Zika virus (ZIKV) from cerebral tissue. We obtained an amplicon of 100 bp for ZIKV in 2 samples, representing a prevalence of 4.4%. An amplicon of 581 bp for RABV was observed in 9 individuals, which is equivalent to 20% of our sample. We obtained 4 different haplotypes for RABV and a single haplotype for ZIKV. We did not record the presence of DENV and CHIKV. We corroborated the presence of the family Rhabdoviridae in the vampire bat and recorded the presence of ZIKV for the first time in this bat species.
Variación estacional y nictémera en la distribución de Beloniformes (Pisces) en la boca de una laguna costera tropical
Authors: Castillo-Rivera Manuel , Morgado-Dueñas Guadalupe
Published: November 2022

El objetivo del estudio es analizar los patrones temporales en la distribución de Beloniformes en un estuario intermitente tropical. Durante 19 meses se realizaron muestreos en ciclos de 24 h cada mes, tomando muestras cada 2 horas (442 muestreos en total). Simultáneamente, se registraron in situ variables abióticas y bióticas, así como variables con registros histórico-regionales. Se capturaron 6 especies, de las cuales Strongylura notata notata mostró un pulso significativo en mayo-agosto, mientras que S. timucu, Hyporhamphus unifasciatus e H. meeki mostraron pulsos significativos en febrero-abril y diciembre (Permanova, p < 0.04). De acuerdo con las correlaciones inter-set de un análisis de correspondencia canónica, la presencia estacional de S. notata notata estuvo principalmente determinada por días largos, altas temperaturas atmosféricas y precipitaciones, mientras que S. timucu e H. unifasciatus se relacionaron con el fitoplancton y zooplancton. Solo S. notata notata presentó diferencias significativas a nivel nictémero (Permanova, p < 0.0005). Las variables histórico-regionales mostraron mayor influencia sobre los patrones de distribución de las especies, que las variables in situ. Un muestreo intensivo permitió conocer de forma más completa las condiciones que determinan los patrones de migración, lo cual contribuye a la conservación y manejo de estas especies.
An Overview of Laboratory Diagnosis of Central Nervous System Viral Infections
Authors: Syed Hussin Sharifah Aliah Diyanah , Chua Ang-Lim , Al-Talib Hassanain , Sekaran Shamala Devi , Wang Seok Mui
Published: November 2022

Central nervous system (CNS) infection is a serious illness that can lead to death. CNS infections include meningitis, encephalitis, brain abscesses and myelitis. These diseases are caused by causative agents like bacteria, fungi, parasites, and protozoa, but most commonly by viral infections. To combat this issue, accurate diagnosis of etiological agents at an early stage is crucial for appropriate treatment, control of the disease and prevent from becoming life-threatening to the patients. This review paper summarises the main laboratory diagnostic methods for CNS infections caused by viruses ranging from conventional to molecular methods. Conventional isolation methods are considered the ‘gold standard’ as they provide accurate evidence, but require highly skilled personnel, are time-consuming, critical in cell type selection and are useless for non-cultivable viruses. Electron microscopy allows recognition of viral morphology and ultrastructural details as the principle of virus identification through negative staining or thin section technique (suitable for tissue or cell specimens). However, it offers low sensitivity and requires at least 106 virions per millilitre or milligram in the specimen to be detectable by microscopy. Immunological-based methods have been extensively applied for viral diagnosis by detecting the antiviral antibodies or viral antigens in clinical samples. While these methods provided high sensitivity and specificity, the incubation and window period of an infection may give false-negative results. Lastly, molecular detections have many advantages such as high sensitivity, specificity, rapid, require a small amount of sample, simultaneous detection of multiple different viruses, and produce both qualitative and quantitative results.
Study of Partial Replacement of Coarse Aggregate in Concrete by Different Proportions of Un-Treated Waste Tyre Rubber
Authors: Phadtare Mr. Jaydeo , Patil Dr. N. K. , Katdare Dr. A. D.
Published: November 2022

Abstract: The aim of this paper is to find out the effect of partial replacement of coarse aggregate by waste tyre rubber in untreated condition that is as it is without any pre-surface treatment. With the help of tests such as compressive strength, spilt tensile strength, flexural strength and slump cone test. In India number of vehicles are growing day by day so, because of it waste tyre generation also increased. So, recycling of this large quantity waste is not an easy work. Our main focus is to use this waste tyre rubber in concrete without affecting its properties which are mentioned earlier. Study and Analysis of partially replaced concrete with respect to various strengths under 7 and 28 days of curing
An Experimental Investigation on HPC Using Basalt Rock Fiber
Authors: V Deepal , K Rachith
Published: November 2022

Abstract: The effect of using basalt fibers on the fresh, mechanical and durability properties of concrete was investigated in this study. The study was performed using different basalt fiber volume fractions of 0.5%, 0.7%, 1%, and 1.5 %, with water/cement (w/c) ratios and 0.40 is utilized. The results were compared to conventional concrete with various percentage of basalt fibers volume fractions. The testing for fresh properties included slump and unit weight tests; mechanical properties testing included compressive strength tests, split tensile strength tests, and flexural strength tests, durability testing included rapid chloride penetration test, water permeability, water absorption, SEM and EDS and XRD tests. The test results showed that the use of basalt fibers reduces slump values as the fiber volume fraction increases; however, with the use of the appropriate amount of High Range Water Admixture (HRWA), target slump values can be achieved. Moreover, a considerable improvement in the compressive, tensile, flexural, average residual strength and durability properties was achieved in case of using basalt fibers. On the other hand, corrosion rates increased with the increase in fiber volumes. However, it can be concluded that utilizing a 0.70% fibers volume fraction is the optimum ratio with an overall acceptable performance with respect to mechanical and corrosion properties.
Developing ESP based-digital learning materials support students’ needs at Indonesian vocational schools: Perceived quality
Authors: Fadlia Fadlia , Asra Surya , Zulida Evi , Santosa Made Hery
Published: November 2022

The purpose of incorporating digital learning materials into vocational school English instruction is to assist students in acquiring specific competencies. Additionally, prepared digital learning materials are intended to assist teachers in developing instructional materials that follow the principles of English for Specific Purposes (ESP) in vocational high schools (SMK). The research used the qualitative research and development (R&D) method. The stages of developing this teaching material model are adapted from Thiagarajan, Semmel, and Semmel's 4Ds model (1974), which consists of four stages: define, design, develop, and disseminate. As data sources, the participants were two teachers from two different vocational schools with a combined enrolment of 115 students. This research's results are a model for developing digital-based teaching materials (prepared digital learning materials). Furthermore, it was discovered that using the prepared digital learning materials greatly aided teachers in teaching English to achieve specific competencies. From the students' perspective, they admitted that it was also exciting because they perceived learning as distinct from traditional   learning materials due to digital materials usage.
English vocabulary learning strategies of university students in Papua
Authors: Komari Komari , Suryanto Suryanto , Hanum Upi Laila
Published: November 2022

This study investigated vocabulary learning strategies (VSL) used by university students in Papua and the relationship between VSL use and English learning achievement. It employed quantitative and qualitative approaches. Quantitative data was collected using Takač's questionnare of VLS and analysed by applying Oxford's Taxonomy of Language Learning Strategies (LLS). Three hundred and thirty-six students majoring in English department and non-English department participated in the questionnaire. Twelve students and six English teachers contributed their perspectives as qualitative data on the learning and teaching of vocabulary at their universities. Key findings included: memory strategies and compensation strategies were the most frequently used strategies; students majoring in English used a wider range of strategies and used them more frequently than did students majoring in other fields of study; high-achieving students used a wider range of strategies and used them more frequently than their low-achieving counterparts; the majority of students were interested in learning new vocabulary through games, songs, movies, role-plays, and using vocabulary cards; more emphasis on VLS instruction need to be placed.
A Single-Center Retrospective Review of Pediatric Cases of Progressive Transformation of Germinal Centers
Authors: Sadanand Arhanti , Aljudi Ahmed , Bergsagel Daniel John , Keller Frank
Published: November 2022

Background Progressive transformation of germinal centers (PTGC) is a
rare diagnosis characterized by asymptomatic lymph node enlargement. It
has previously been associated with lymphoma, autoimmune conditions, and
lymphoproliferative diseases in small pediatric case series. Procedures
We conducted a single-center retrospective review of pediatric cases of
PTGC diagnosed at our institution by hematopathologists from 2000 -
2020. Results We identified 57 primary cases and 3 recurrent cases of
PTGC. There was a male predominance in cases (32/57), with median age at
diagnosis of 11 years. Head and neck lymph nodes were the most commonly
involved and biopsied sites. Laboratory and imaging evaluations were
obtained inconsistently. Only 16% of patients saw a pediatric
hematology/oncology (PHO) specialist prior to diagnosis and 37% had
follow-up with PHO after diagnosis. Six patients (10%) had a preceding
or concurrent diagnosis of lymphoma and 5% of patients returned with
recurrent PTGC. Conclusions Patients with PTGC had similar
characteristics to those from previous case series. Fewer patients
underwent recurrent lymph node biopsy than previously described. PTGC
has been linked to certain types of lymphoma, although never
definitively associated with lymphoma. Follow-up with a PHO provider is
indicated to ensure that close surveillance is performed.
Enhancing urban runoff modelling using water stable isotopes and ages in complex catchments
Authors: Smith Aaron , Tetzlaff Dörthe , Marx Christian , Soulsby Chris
Published: November 2022

Increased urbanization, coupled with the projected impacts of climatic
change, mandates further evaluation of the impact of urban development
on water flow paths to guide sustainable land use planning. Though the
general urbanization impacts of increased storm runoff peaks and reduced
baseflows are well known; how the complex, non-stationary interaction of
the dominant water fluxes within dynamic urban water stores sustain
streamflow regimes over longer periods of time are less well quantified.
In particular, there is a challenge in how hydrological modelling should
integrate the juxtaposition of rapid and slower flow pathways of the
urban ‘karst’ landscape and different approaches need evaluation. In
this context, we utilized hydrological and water stable isotope datasets
within a modelling framework that combined the commonly used HEC urban
runoff model along with a simple hydrological tracer module and transit
time modelling to evaluate the spatial and temporal variation of water
flow paths and ages within a heavily urbanized 217km
catchment in Berlin, Germany. Deeper groundwater was the primary flow
component within less urbanized regions of the catchments, with
increased direct runoff and shallow subsurface contributions in more
urbanized areas near the catchment outlet. The addition of wastewater
effluent in the mid-reaches of the catchment was the dominant water
supply to the lower stream, and sustained baseflows during the summer
months. Water ages from each modelling approach imitated flow
contributions and opportunity for mixing with subsurface storage; with
older water and lower young water contributions in less urbanized
sub-catchments and younger water and higher young water contributions in
more urbanized regions. The results form a first step towards more
integrated modelling tools for similar peri-urban catchments, given the
potential limitations of more simple model frameworks. The results have
broader implications for assessing the uncertainty in evaluating urban
impacts on hydrological function under environmental change.
Bioleaching of vanadium-bearing shale by chemical mutation of Bacillus mucilaginosus through enhanced organic acids metabolite
Authors: Tian Hongqing , Cai Zhenlei , Zhang Yimin , Zheng Qiushi
Published: November 2022

The recovery and utilization of vanadium from vanadium-bearing shale are
significant, because vanadium is an important strategic metal. This
study explored a cleaner metal extraction method to recover vanadium
from vanadium-bearing shale using a novel strain of mutated Bacillus
mucilaginosus (B.M) and an enhanced bioleaching process. The
high-efficient bioleaching bacteria of B.M-0.2 was obtained by the
chemical mutation of hydroxylamine hydrochloride. The optimal conditions
for extracting vanadium by the mutant bacteria were 0.5g/L ammonium
nitrate, 5g/L sucrose, at pH 7.5, and the ore particle size of -0.074mm
accounts for 92.34%, the pulp density was 10g/L, and the vanadium
leaching efficiency of B.M-0.2 was 8.16% higher than that of the
original bacteria after a 30 days bioleaching period. The results showed
that the mutant B.M-0.2 had the highest acid production. The total
content of the organic acid produced by B.M-0.2 was nearly three times
than that compared with the original strain after 2 days. The gene of
the mutant B.M0.2 was sequenced by Polymerase Chain Reaction sequencing
technology, and it was found that the mutant still belongs to the
Bacillus family but the gene of the mutant was obviously changed. The
results showed that the mutated B.M through the chemical mutation of
hydroxylamine hydrochloride had great potential to improve the vanadium
recovery from vanadium-bearing shale.
Research on Hybrid Magnetic Bearing Control Method Based on Particle Swarm Optimization Fuzzy-PID Controller
Authors: Feng Xiong , Jingchang Han , Yan Li
Published: November 2022

This paper aims at increasing the control effect of hybrid magnetic
bearings(HMB). In this paper, a Fuzzy-PID control algorithm is used to
control the HMB with complex and multivariate characteristics. And the
Particle Swarm Optimization (PSO) algorithm is combined to optimize the
scale factor parameters of the Fuzzy controller to solve the problem of
fixed parameters of the Fuzzy controller, which leads to the limitation
of control accuracy. A Simulink model of the HMB system considering the
mass of the rotor is built, and the response of the rotor to float and
the response under the action of external disturbance forces are
simulated respectively. The results show that after optimisation by the
PSO algorithm, the system responds quickly, with small overshoot and
high stability, which achieves better control results in the process of
rotor displacement control of the hybrid magnetic bearing support.
Analytical and numerical solutions of time and space fractional diffusion-reaction equation
Authors: Zhang Peng , Du Wenli , Li Ping , Xiu Guohua , E Alirio Rodrigues
Published: November 2022

ABSTRACT The anomalous diffusion and reaction process for
Riemann-Liouville fractional differential equation is studied for
heterogeneously isothermal nth-order reaction. The diffusion
coefficient is regarded as a function of the position of the fractal
porous catalyst. For a first-order irreversible reaction, new general
analytical solutions of transient concentration profiles are derived
with Mittag-Leffler function by taking into account of the intraparticle
and external mass-transfer resistances. The numerical solution for
anomalous diffusion-reaction is present for nth-order reaction;
it is found that the results calculating by numerical solution are in
satisfactory agreement with those by analytical solution for first-order
reaction. The volume-averaged concentration and general expressions for
effectiveness factor are present for first-order reaction. The effects
of the order of the time fractional derivative, the fractal geometry of
porous catalyst, diffusion coefficient, intraparticle and external
mass-transfer resistances, and Thiele modulus on transient concentration
profiles and catalytic efficiency are examined over a wide range of
parameters by analytical solutions and numerical solution.
Filum terminale paraganglioma with leptomeningeal dissemination: a case report
Authors: Freitas Pedro , Miguel Isália , Moreira António
Published: November 2022

Leptomeningeal dissemination of a paraganglioma is an extraordinarily
rare phenomenon described in a small number of cases worldwide. Here, we
report a case of filum terminale paraganglioma characterized by an
indolent, insidious nature even in the setting of leptomeningeal
dissemination.
A local search algorithm with hybrid strategies for the maximum weighted quasi-clique problem
Authors: Zhou Jincheng , Liu Shuhong , Gao Jian
Published: November 2022

Identifying cohesive subgraphs is an important topic in graph theory and
complex network analysis. The quasi-clique, as a generalization of
clique, can be used to identify functional and structural properties of
various networks. In this paper, we study the maximum weighted
quasi-clique problem, and propose a local search algorithm for solving
the problem. In the algorithm, an iterated local search method is used
as the search framework. To find the quasi-clique with the maximum total
weights, hybrid vertex selection strategies are proposed and
incorporated into our algorithm. The hybrid strategies utilize a
probability-based mechanism for choosing sub-strategies in each round of
the local search. We conduct experiments on synthetic networks and
real-world networks to show the effectiveness of our algorithm. The
results indicate that hybrid strategies perform better than existing
methods, and thus our algorithm has a good ability to tackle various
networks.
Pulmonary artery sling: An overview.
Authors: Durward Andrew , K Muhammed Riyas Rahmath
Published: November 2022

Pulmonary artery sling is a rare childhood vascualr ring that is
frequently associated with tracheal stensois. Consequently, neonates may
present with a crictal airway obstruction if tehre is long segemt
tarcheal stensosi and complete rings. Rapid diagnosis of this cardiac
vascular malfomation and extent airway involvement is essentail as
longterm outcoem can be excellent follwoing surgicla repair. In this
review we focus on airway invetsigation and management for this
challenging congential condition.
Efficacy of cell-culture derived Influenza vaccines for children: A systematic review and meta-analysis
Authors: Singh Meenu , Kaur Kulbir , Sachdeva Meenakshi , Rana Monika , Chauhan Anil , Bhatia Ragini , Pradhan Pranita , Saini Shivani
Published: November 2022

Objectives: To determine the efficacy of cell culture based
influenza vaccines in children. Methods: Embase, PubMed,
Cochrane and clinical trials were searched.14 randomised controlled
trials in children were selected. The current systematic review was done
as per the PRISMA guidelines. The pooled estimate of seroconversion and
GMT rate was calculated as mean difference. Data was analysed using the
Cochrane Collaboration Review Manager Version software. Risk of bias was
done as per Cochrane risk of bias tool. The quality of evidence was
adjudged using Grading of Recommendations, Assessment, Development, and
Evaluation (GRADE) using the Grade pro software. Results:
Significant results for efficacy were reported for half dose MF59
influenza vaccine control group for GMT at day 1 with a mean difference
of 0.78, 95%CI, 0.50 to 1.07, p<0.00001 as compared to full
dose MF59 influenza vaccine experimental group .No significant results
were reported in half dose MF59 influenza vaccine for GMT at Day 43(mean
difference 151.57,95% CI,-29.36 to 332.50 ,p=0.10). Significant results
were reported for seroconversion rate for half dose MF59 influenza
vaccine control group at day 22 with a mean difference of
17.92,95%CI,10.08 to 25.75,p<0.00001 as compared to half dose
MF59 influenza vaccine group at day 43 with a mean difference of
5.00,95%CI,-4.80 to 14.80,p=0.32 . Conclusion: The current
systematic review demonstrated that half dose cell derived influenza
vaccines was well tolerated and more immunogenic and resulted in high
seroconversion rate and Geometric Mean Titres rate in paediatric
population.
Parameter estimation based on novel enhanced self-learning particle swarm optimization algorithm with Levy flight for PMSG
Authors: Feng Wan , Li Mengdi , Zhang Wenjuan , Haixia Zhang
Published: November 2022

A novel parameter estimation method is proposed for the permanent magnet
synchronous generator (PMSG), which is implemented by an enhanced
self-learning particle swarm optimization algorithm with Levy flight
(SLPSO), and the problem of lower parameter estimation precision of
standard PSO is obviated. This method injects currents of different
intensities into the d-axis in a time-sharing manner to solve the
problem of equation under-ranking, and the mathematical model for
full-rank parameter estimation is developed. The speed term of PSO is
simplified to expedite the convergence of PSO, and a strategy with
Chaotic decline for the inertia weight of PSO is adopted to strengthen
its ability to jump out of the local optimum. Moreover, the
self-learning dense fleeing strategy (SLDF) is proposed where particles
perform diffusion learning based on population density information and
Levy flight, the evolutionary unitary problem and human intervention in
the evolutionary process is averted. Furthermore, the memory tempering
annealing algorithm (MTA) and greedy algorithm (GA) is integrated into
the algorithm, MTA can facilitate the exploration of potentially better
regions, and GA for local optimization enhances the convergence speed
and accuracy in late stage of the algorithm. Comparing the proposed
method with several existing PSO algorithms through simulation and
experiments, the experimental data show that the proposed method can
effectively track variable parameters under different working conditions
and has better robustness.
Temporal Dengue Outbreak Prediction from Climatic Variables using Finite Element Machine for Regression
Authors: Passos Leandro , Lydia M. , Kumar G. Edwin Prem , Ravichandran Akash , Martins Guilherme Brandão , Papa Joao
Published: November 2022

The global burden of dengue, a mosquito-borne viral infection,
has alarmingly increased in recent decades. The rise in disease
occurrence is mainly attributed to changes in the climate, human
ecology, globalization, and demography. In such a scenario, an accurate
prediction of a dengue outbreak is essential to reduce the morbidity
rate significantly. Therefore, this paper employs two classes of
autoregressive models for dengue forecasting and a recently proposed
approach called Finite Element Machine for Regression (FEMaR). Further,
it proposes a variant of the latter, namely FEMaR-KD, which allows the
exploration of k -approximate nearest neighbors to interpolate data
points based on k -neighborhood instead of the whole dataset. Such
models are built considering environmental parameters, which denote one
of the main determinants for infection occurrence. Finally, the proposed
models’ performance is assessed over two distinct datasets, considering
differing spatial scales and regions. Results show that FEMaR obtained
Mean Absolute Error up to 51% smaller than the autoregressive
models considering univariate scenarios and Root Mean Squared Error up
to 63% smaller regarding the univariate models.
PENINGKATAN MOTIVASI BELAJAR DAN PENGUASAAN KONSEP KIMIA PADA TOPIK HIDROLISIS GARAM DAN LARUTAN PENYANGGA MELALUI PEMBELAJARAN INKUIRI TERBIMBING
Authors: Merta Luh Maharani
Published: November 2022

Penelitian ini bertujuan meningkatkan motivasi belajar dan penguasaan konsep kimia siswa kelas XI IPA5 SMA Negeri 4 Singaraja melalui penerapan model pembelajaran inkuiri terbimbing. Jenis penelitian ini adalah penelitian tindakan kelas. Subjek penelitian ini siswa kelas XI MIPA5 SMA Negeri 4 Singaraja, berjumlah 39 orang dan objek penelitian ini adalah motivasi belajar dan penguasaan konsep siswa. Penelitian tindakan kelas ini dilaksanakan dalam dua siklus; setiap siklus terdiri atas empat tahap meliputi perencanaan, pelaksanaan, observasi/evaluasi, dan refleksi. Tes hasil belajar digunakan mengukur penguasaan konsep siswa, inventori digunakan untuk mengukur motivasi belajar siswa, dan angket digunakan untuk mengukur pendapat siswa terhadap model pembelajaran yang diterapkan. Data penguasaan konsep kimia dan motivasi belajar siswa dianalisis secara deskriptif. Hasil penelitian ini menunjukkan bahwa penerapan model pembelajaran inkuiri terbimbing dapat meningkatkan motivasi belajar dan penguasaan konsep kimia dari siswa. Hal ini dapat dilihat dari peningkatan skor rata-rata motivasi belajar siswa dari 2,39 dengan kategori cukup pada Siklus 1 menjadi 3,53 dengan kategori sangat tinggi pada Siklus 2. Demikian juga, skor rata-rata penguasaan konsep kimia dari siswa dari 74,36 pada Siklus 1 menjadi 79,90 pada Siklus 2. Siswa setuju dengan model pembelajaran yang diterapkan. Mereka berharap agar model pembelajaran ini dapat digunakan untuk mengajarkan konsep-konsep kimia yang lain.