bluuebunny/crossref_metadata_2025 huggingface dataset:
User Experience Evaluation of Botani Mobile Application using User Experience Questionnaire
Authors: Priandani Nurizal Dwi , Sandy Yohana Avelia , Sari Nadia Roosmalita
Published: July 2023

Agriculture is an important sector in Indonesia. Farming are how most people make a living within the population [1]. Currently, access to consult with agricultural experts is something that farmers don't have as a privilege. The combination of technology and agriculture needs to be developed to make it easier for farmers to consult. Botani Mobile Apps is an Android-based application that has been developed by the Faculty of Agriculture UB. The purpose of this application is to facilitate farmers in agricultural cultivation. User experience is how a person feels when using a product, system, or service [2]. User experience evaluation needs to be done to measure the success of a product design and to get user feedback for further improvement. One method of evaluating user experience is UEQ (User Experience Questionnaire). Evaluation of user experience of the Botanical mobile application using UEQ will be discussed in this study. Based on the results of the UEQ that have been carried out, the 26 questions asked had an average value of more than 1. After grouping the questions on the 6 UEQ Scale, the average results of calculation showed that all scales are in the green area. Based on UEQ characteristics, the highest scores were Attractiveness, Pragmatic and Hedonic qualities, respectively. All the results of the characteristic values were more than 1. Based on the Benchmark calculation, showed that the Attractiveness, Efficiency, Dependability and Novelty scales had good scale results and the Perspicuity and Novelty scales got above average scale results. Based on all the results of the UEQ evaluation, it can be concluded that the user experience on the BOTANI application is good.
Prediksi Pergerakan Saham BBRI ditengah Issue Ancaman Resesi 2023 dengan Pendekatan Machine Learning
Authors: Utomo Wahyu Cahyo
Published: July 2023

The economic recovery after the Covid-19 pandemic is becoming increasingly challenging. According to several experts, a global recession is expected to occur in 2023, necessitating contributions from various fields of knowledge to address this situation. Machine learning is one method that can contribute by forecasting stock price movements. This research attempts to address the issues faced by traders in observing the potential movement of BBRI stock under the recession issue in 2023. Furthermore, this study uses linear regression and Bayesian regression methods to find the best model. By using six-month stock data of BBRI, with attributes such as open, high, low, and close as prediction targets, it is found that the model built using linear regression outperforms Bayesian regression. Based on the testing results, the linear regression model achieved a Dstat of 80% and an RMSE of 595.30, while the Bayesian regression model obtained a Dstat of 80% but a higher RMSE of 660.58. Based on the modeling results in this study, it is concluded that in the first semester of 2023, BBRI stock is still moving upward and is not affected by the recession issue in 2023.
Enhancement of Coronary Heart Disease Prediction using Stacked Long Short Term Memory
Authors: Cinthiya Cinthiya , Oetama Raymond Sunardi
Published: July 2023

The high incidence of death caused by coronary heart disease has become a global concern in the world of health, where patients with coronary heart disease are no longer only adults and the elderly, yet there are now so many cases of coronary heart disease experienced by underage patients. As a result, it is critical to be able to prevent and reduce the number of instances. One of them is the ability to predict a person's risk of coronary heart disease so that patients can be treated and provided early therapy. The risk of coronary heart disease will be predicted in this study utilizing Stacked long short-term memory algorithms. By appling this algorithm, the accuracy of 81.3% from previous study can be increased to 91.8% by this study.
PREPARATION OF NEW SERIES OF TETRADENTATE SCHIFF BASE COMPLEXES AND STUDING THEM SPECTROSCOPICALLY, BIOLOGICALLY AND THEORETICALLY
Authors:   1Master,s  student , Department of Chemistry, College of Science for Women, University of Baghdad, Baghdad Iraq. wedad.hameed1205a@csw.uobaghdad.edu.iq, Majeed Wedad  H. , Baqer Shaymaa R. ,   2Assistant professor, Department of Chemistry, College of Science for Women, University of Baghdad, Baghdad Iraq. shaimaarb_chem@csw.uobagdad.edu.iq
Published: July 2023

This new Schiff base ligand (L) were prepared from condensation reaction of 3-amino-4-(1-methoxy-1-oxo-3-phenylpropan-2-ylamino)-4-oxo butanoic acid(aspartame) with 4-(dimethyl amino benzaldehyde). A series of complexes of divalent, trivalent and tetravalent ions were prepared. The ligand and the prepared complexes of cobalt, nickel, copper, palladium, platinum and gold have been characterized by several techniques such as C.H.N.O, FT-IR, molar conductivity, UV– visible, magnetic moment, 1H-NMR and 13C-NMR. Experimental findings demonstrated that the ligand formed tetra-dentate coordination with the metal ions. The biological activity was studied by using two types of gram positive Staphylococcus aureus, Bacillus subtilis, and gram negative bacteria E. coli, Klebsiella with one type of fungi candida at a concentration of 0.02 M. The results showed that the prepared metal complexes and ligand are more effective than the standard drug in bacteria and fungi. The molar ratio method was used to calculate the ratio of metal to ligand. The experimental results have proven its interaction in a ratio of (1:1). Additionally, the hyper-Chem 8.0.7 program was used to calculate the binding energy and the standard heat of formation of the ligand(L) and all prepared complexes, in addition to calculating the vibration frequency of the ligand, also HOMO and LUMO.
THE DETECTION OF SOME MINERALS IN INFANT FORMULA AVAILABLE IN LOCAL MARKETS.
Authors:   Assistant Professor, PhD, Market Research and Consumer Protection Center, University of Baghdad, Baghdad, Iraq, alia.sadon@yahoo.com, Al-Faraji. Aliaa Saadoon Abdul-Razaq
Published: July 2023

This study was conducted in Baghdad Governorate for the period from February to August 2021 for the purpose of investigating the levels of some minerals such as calcium, iron, zinc, copper and lead in powdered infant formula available in local markets and comparing them with the permissible international, Arab and Iraqi levels. The study included the examination and analysis of (10) ten samples of powdered infant formula for different brands: (Similac Gold 1, 2 and 3) (Kikoz 1, 2and 3) (Dielac 1) and (Novalac Genio and 2). The results showed variations in the concentration of calcium, iron, zinc, copper and lead. The results of these levels in the concentrations of some minerals are than the permissible limits, and thus the above models are suitable for human consumption.
EFFECT OF ADDING DIFFERENT LEVELS OF ONION (Allium cepa linn) POWDER TO BROILER DIETS ON THE PHYSIOLOGICAL CHARACTERISTICS
Authors:   1Researcher, Animal production department, College of Agricultural engineering science, university of Baghdad, Iraq, Email: Omar.nazeer1201a@coagri.uobaghdad.edu.iq, Alani Omar Nather , Mashhdani Hanan Essa Al ,   2Assistant Professor, Animal production department, College of Agricultural engineering science, university of Baghdad, Iraq, Hanan.e@coagri.uobaghdad.edu.iq
Published: July 2023

Between October 15, 2021, and November 26, 2021, this study was carried out in the broiler field at the College of Agricultural Engineering Sciences, University of Baghdad in Abu Ghraib to examine the effects of adding various dosages of onion powder, "Allium cepa linn", to broiler chicks' diets on the physiological characteristics. The experiment employed 225 unsexed (Ross 308) one-day-old broiler chicks with an average weight of 40g. A total of 225 chicks were divided into 5 treatments by three replicates in each treatment with 15 chicks per replicate randomly. The experimental treatments were as follows: The chicks were first fed starter ration from one day old to 21 d old, after which they were fed a finisher diet from 22 to 42 d old. The treatments were described as T1 (control treatment): basal diet without onion powder addition, T2: basal diet with 2g/kg of onion powder/kg of feed, T3: basal diet with …….. 4g/kg of feed of onion powder as part of the T3 treatment. Both the T4 treatment and the T5 treatment added onion powder at rates of 6g and 8g per kilogram of feed, respectively. The experiments findings suggested the following: There was a significant decrease (P<0.05) in the level of serum cholesterol concentration for the T2 treatment compared to that of the T1 controlled treatment. However, the T2 treatment did not differ significantly with the T3, T4 and T5 treatments. When comparing the level of the liver enzymes AST and ALT for the T5 treatment to that of the T1 controlled treatment, there was a significant improvement (P<0.05). While there was little difference between the T5 treatment and the T2, T3, and T4 treatments.
Microbiological screening of compounds with potential anti-lep activity among new synthesis compounds of the pyrimidine series
Authors: Lutsenko A. V. , Yushin М. Yu. , Genatullina G. N. , Tyrkov A. G. , Ayupova A. K. , Saroyants L. V. , Starikova A. A. , Samotrueva M. A.
Published: July 2023

Aim: To study the effect of new synthesized pyrimidine derivatives on the growth of Mycobacterium lufu (M. lufu) and Mycobacterium tuberculosis (M. tuberculosis) when cultivated on Shkolnikova’s medium.Materials and methods. The objects of research were new synthesized derivatives of 6 samples of derivatives of pyrimidine - 5-(arylmethylidene)-2,4,6-pyrimidine-2,4,6(1H,3H,5H)-trions under laboratory codes TAG1, TAG2, TAG3, TAG4, TAG5, TAG6 and 7 samples of 5-(getarylmethylidene)-2,4,6-pyrimidine-2,4,6(1H, 3H, 5H)-trions under the laboratory codes TAG7, TAG8, TAG9, TAG10, TAG11, TAG12, TAG13. M. lufu and M. tuberculosisH37Rv strains were used as test cultures. The antimycobacterial activity of the studied compounds was studied by the method of serial dilutions.Research results. All studied compounds were found to exhibit antimycobacterial activity. The greatest inhibitory effect against M. lufu was noted for TAG1, TAG4, TAG7, TAG12, and TAG13, which was comparable to that of the reference drug dapsone. By the nature of the inhibitory effect on the growth of M. tuberculosis, the compounds under the laboratory codes TAG 1, TAG 4, TAG 7 and TAG13 were comparable to isoniazid, and the effect of the TAG3 compound was even slightly superior to the reference drug.Conclusion. Among the studied new synthesized pyrimidine derivatives, compounds under the laboratory codes TAG1, TAG4, TAG 7 and TAG13 have the most pronounced antimicrobial activity both against M. lufu and M. tuberculosis, which allows us to consider them as the most promising substances for further research on the search for antimycobacterial, including antileprosy drugs.
Cytokine profile in patients with obstructive coronary artery disease
Authors: Atamas O. V. , Antonyuk M. V.
Published: July 2023

Background. Studies of the role of cytokines in the pathogenesis of coronary artery disease (CAD) are quite relevant. Significant cytokine imbalance is mostly observed in patients with acute coronary syndrome. However, there are limited reports of serum cytokine levels in patients with chronic stable CAD. The problem of relationship between cytokines to the severity of coronary atherosclerosis is still urgent.Aim: To investigate the relationship between serum levels of cytokines and the severity of CAD.Material and Methods. Serum levels of IL-2, IL-4, IL-6, IL-10, TNF-a was analyzed in 24 healthy control patients and 70 patients with stable CAD who underwent coronary angiography. Coronary atherosclerosis was assessed with Gensini scoring system. Depending on the median of GS (38.0), the patients were divided into moderate CAD group (GS = 8–37) and severe CAD group (GS ≥ 38). The data were analyzed using Statistical Package for the Social Sciences (SPSS) software 26.0.Results. Patients with obstructive CAD presented higher TNF-α levels and lower IL-4. Patients with severe CAD increased IL-6 and reduced IL-2 levels. Logistic regression analysis showed that the IL-6 was independently related to the presence of obstructive CAD (OR = 3.836; 95% CI= 1.8–8.177). ROC analysis of the IL-6 logistic regression model showed that a cut-off of 5.19 pg/mL had 75.0 % sensitivity and 70.0 % specificity to predict severe atherosclerosis.Conclusion. Pro-inflammatory TNF-α and IL-6 cytokines increased, while regulatory IL-2 and anti-inflammatory IL-4 decreased in patients with stable CAD. Cytokine imbalance contributes to CAD progression. Elevated IL-6 levels and the pro-inflammatory potential of the blood increases in case of severe coronary atherosclerosis. It has been shown that with an increase in IL-6 levels, the odds of detecting severe CAD increases 3.5-folds.
Preventive use of glycoprotein IIb/IIIa inhibitors in patients with ST-segment elevation myocardial infarction and a high risk of no-reflow phenomenon
Authors: Bessonov I. S. , Shadrin A. A. , Sapozhnikov S. S. , Ryabov V. V. , Popov S. V.
Published: July 2023

Aim: To evaluate the efficacy and safety of the preventive use of glycoprotein (GP) IIb/IIIa inhibitors in patients with ST-elevation myocardial infarction (STEMI) and a high risk of «no-reflow» phenomenon.Material and Methods. A total of 100 patients were included in the study. For all patients, the risk of no-reflow was calculated using a previously developed scoring system. In case of high risk, GP IIb/IIIa inhibitors were administered according to the decision of the interventional cardiologist. The rate of no-reflow as well as the rates of death, recurrent myocardial infarction and stent thrombosis were analyzed.Results. High risk of no-reflow was determined in 37 patients, low risk of no-reflow – in 63 patients. In the high-risk group 22 patients (59.5%) GP IIb/IIIa inhibitors were preventively used. In these patients, the frequency of no-reflow was lower compared with high-risk patients who did not receive preventive GP IIb/IIIa inhibitors (9.1 vs. 46.7%, p = 0.017). With the preventive use of GP IIb/IIIa inhibitors in high-risk patients, the rates of no-reflow (9.1 vs. 11.1%, p = 1.000) and angiographic success of percutaneous coronary intervention (72.7 vs. 84.1%, p = 0.341) were comparable with low-risk patients.Conclusion. The preventive use of GP IIb/IIIa inhibitors in patients with STEMI and a high risk was associated with reduction of «no-reflow». In the prophylactic use of GP IIb/IIIa inhibitors in patients with STEMI and a high risk of no-reflow, the results of their treatment were comparable to patients with a low risk of no-reflow.
Left atrial strain in acute myocardial infarction
Authors: Beishenkulov M. T. , Toktosunova A. K. , Kaliev K. R. , Kolbai A. , Madyarova Y. M.
Published: July 2023

Background. The ejection fraction (EF), diastolic dysfunction of the left ventricle (LV) and its volumes play the main role for prognosis assessment. Measurement of left atrial strain is a new method of noninvasive investigation of mechanical function.Aim: To investigate the mechanical function of the left atrium in patients with acute myocardial infarction (AMI) with different degrees of left ventricular ejection fraction reduction.Methods. We studied 60 patients with acute ST-segment elevation anterior myocardial infarction. Echocardiography was performed in the first day of acute infarction. The left atrium was assessed by phase volumes, as well as by strain and strain rate using speckle-tracking. 35 healthy subjects were investigated for control. The patients were divided into 4 groups: Group 1 – LV EF 50–60%, Group 2 – LV EF 40–49%, Group 3 – LV EF 30–39%, Group 4 – LV EF 20–29%.Results. There were no significant differences in left atrial volumes between patients in groups 1–3 and healthy patients. Left atrial volume was increased in the fourth group. In the first group, peak longitudinal atrial strain (PALS) was significantly reduced compared with control group (PALS 22% vs 32.4%, p < 0.000). In the second group PALS was 17.41%, in the third group it was 18.19%. In the group with LV EF less than 30%, PALS was 4.43%. In healthy subjects, the strain rate was – 2.14 cm/s-1, in Group 1 – 2.15 cm/s-1 (p < 0.297), in Group 2 – 1.19 cm/s-1(p < 0.000), in Group 3 – 1.58 cm/s-1 (p < 0.000), and in Group 4 – 1.14 cm/s-1(p < 0.000).Conclusion. In patients with AMI with LV EF more than 50%, significant violations of LA strain are detected, which may be a predictor of left heart dysfunction. As the LV EF decreases, LA strain decreases and LA volume increases.
Macrophages of the cardiosplenal axis and their content in patients with myocardial infarction
Authors: Kercheva M. A. , Ryabov V. V. , Trusov A. A. , Stepanov I. V. , Kzhyshkowska J. G.
Published: July 2023

The spleen is one of the main reservoirs of monocytes, the leading cells of the post-infarction inflammatory response.Aim: To assess features of splenic macrophage infiltration, its dynamics and correlations with myocardial macrophage infiltration and an adverse course of the myocardial infarction (MI)Material and Methods. The macrophage composition of spleen and myocardium sections of patients (n = 30) with fatal MI and persons from the control group without cardiovascular disease (n = 5) was assessed by immunohistochemistry.Results and conclusion. All investigated cells, as CD68+, CD163+, CD206+, and stabilin-1+ were represented in the spleen regardless of the presence of MI. Their number in spleen in patients with MI remained consistently high regardless of the period of MI, and was accompanied by an increased number of such cells in the infarction area of myocardium. CD68+, CD163+ and stabilin-1+ cells predominated in the red pulp in patients with fatal MI, its number many fold exceeded that in the control group and that in the white pulp and in the infarction area of myocardium. In the white pulp of patients with fatal MI, the number of CD68+ cells predominated, in persons from the control group – CD163+. We revealed only one cell types whose content in the spleen in the control group was higher than in individuals with fatal MI – CD206+in the red pulp. Low content of CD206+ cells in the red and white pulp of the spleen characterized patients with a fatal outcome of MI.
Complications of permanent pacing in children depending on the method of implantation
Authors: Kartofeleva E. O. , Plotnikova I. V. , Svintsova L. I. , Dzhaffarova O. Yu. , Perevoznikova Yu. E.
Published: July 2023

Background. Currently pacing is the only treatment option for life-threatening bradyarrhythmias. Considering the specific factors of pediatric patients, specialists in this field should be highly professional.Aim: To present the experience and retrospective analysis of complications of permanent pacing in children and adolescents from Tomsk National Research Medical Center.Material and Methods. Complications of permanent pacing in children with structurally normal heart and children with congenital heart defects were analyzed. The follow-up was from 1999 to 2021 years. 256 patients aged from 1 month to 18 years participated in the study. Epicardial pacemaker was implanted in 173 children, endocardial – in 83 patients. Average time from primary implantation to complications was 2.1 ± 2.7 years.Results. Hemodynamic complications are the most common among patients with epicardial and endocardial permanent pacing. Hemodynamic complications with epicardial permanent pacing are associated with intraventricular dissynchrony due to stimulation in the area of the lateral wall or the right ventricular outflow tract. In patients with endocardial permanent pacing hemodynamic complications are associated with the development of pacemaker-induced cardiomyopathy due to permanent pacing of the right ventricle apex and tricuspid regurgitation. Complications such as bacterial endocarditis, infection of the pacemaker and its bed, hemopericardium, subclavian vein occlusion, pericarditis, peacemaker dislocation and lead fracture were less common. Two cases of cardiac strangulation were detected.Conclusion. Neither epicardial nor endocardial pacemaker implantation guarantee the absence of complications. Implantation of the electrode on the apex of the left ventricle (epicardial pacemaker system), in the area of the His bundle (endocardial pacemaker system), prevents the development of hemodynamic complications. The most rational is the use of a primary epicardial pacemaker system. Such approach allows the veins to be preserved for endocardial stimulation at an older age.
Validation of a predictive model of the left atrium appendage thrombosis in patients with nonvalvular atrial fibrillation
Authors: Belokurova A. V. , Gizatulina T. P. , Khorkova N. Yu. , Mamarina A. V. , Martyanova L. U. , Gorbatenko E. A.
Published: July 2023

Aim: To test the previously developed predictive model on a test set, including patients with non-valvular atrial fibrillation (AF).Material and Methods. A predictive model was previously developed on a training set of 638 patients with non-valvular AF. The test set included 175 randomly selected patients with non-valvular AF hospitalized at the Tyumen Cardiology Research Center for radiofrequency ablation (RFA) or electrical cardioversion in 2018-2021. The quality of the predictive model was assessed using ROC analysis.Results. Arterial hypertension, coronary heart disease, congestive chronic heart failure, and persistent AF were more common in patients of both sets with left atrial appendage (LAA) thrombosis. Patients of the training and test sets with LAA thrombus had more pronounced structural changes in the heart cavities and similar changes in the geometry of the heart: normal left ventricle (LV) geometry was less common and eccentric LV hypertrophy was more common. According to the results of a previous retrospective analysis of the data, independent predictors of LAA thrombosis were persistent type of AF, left atrium size, and eccentric LV hypertrophy. Based on the data gathered, a predictive model LAA thrombosis was developed as an equation that includes 3 variables. The cut-off point for calculating the probability of LAA thrombosis is 0.07. Applying this model on a test set showed the good quality of the model: the area under the curve obtained using ROC analysis was 0.750 (p < 0.001). At the same time, the sensitivity and specificity of this model for the detection of LAA thrombosis were 72.3% and 71%, respectively.Conclusion. The evaluation of the quality of the LAA thrombosis predictive model developed on the training set confirmed its good quality on a similar test set of patients with non-valvular AF hospitalized for RFA or electrical cardioversion.
Predictors of the development of cognitive impairment in patients undergoing pulmonary thromboendarterectomy
Authors: Klinkova A. S. , Kamenskaya O. V. , Loginova I. Y. , Porotnikova S. S. , Volkova I. I. , Habarov D. V. , Lomivorotov V. V. , Lomivorotov V. N. , Chernyavskiy A. M.
Published: July 2023

Aim: To study the clinical and functional features, as well as intra- and postoperative indicators of patients with chronic thromboembolic pulmonary hypertension (CTEPH) with the development of negative dynamics of cognitive status in the early postoperative period and to identify pathophysiological factors associated with this disorder.Material and Methods. The study included patients with CTEPH scheduled for pulmonary endarterectomy (PEA). The 1st group (38 people) consisted of patients with the development of negative dynamics of cognitive functions according to the MMSE scale in the early postoperative period, the 2nd group (91 people) – without negative dynamics of cognitive functions. Preoperative clinical, anamnestic data, intraoperative parameters, early postoperative complications and their relationship with the negative postoperative dynamics of cognitive status were analyzed.Results. The average age of patients in the general group was 54.1 (44.3–68.1) years. The 1st group was characterized by older age (p = 0.03), a prevalence of patients with diabetes mellitus (p = 0.02), arterial hypertension (p = 0.04), atherosclerosis of the brachiocephalic arteries ≤ 50% (p = 0.04) and higher level of Charlesson comorbidity index (p = 0.002) in comparison with the 2nd group. Intraoperative factors for the development of postoperative cognitive impairment were a longer circulatory arrest (CA) during PEA and a more pronounced decrease in cerebral oxygenation during CA. The 1st group of patients were characterized by a large number of complications, including pulmonary heart failure (p = 0.02), acute renal failure (p < 0.001) and atrial fibrillation (p < 0.001) in comparison with the 2nd group. The development of negative postoperative dynamics of cognitive status in CTEPH patients was associated with baseline reduced cognitive function – OR 2.3 (1.4–9.2 95% CI) (p = 0.01) and with the presence of three or more CA during PEA – OR 3.2 (1.1–12.7 95% CI) (p = 0.01).Conclusion. Independent factors for the development of negative postoperative dynamics of cognitive status in patients with CTEPH were baseline impairment of cognitive function (< 20 points according to the MMSE scale), three or more CA during PEA, and the development of new-onset atrial fibrillation in the early postoperative period.
Acute myocardial infarction complicated by sudden out-of-hospital cardiac arrest: a clinical case
Authors: Malanin V. A. , Shevchenko I. I. , Ivanov N. M. , Veselova V. V. , Tsurikova A. V.
Published: July 2023

Justification. One of the serious complications of acute myocardial infarction (AMI) is out-of-hospital cardiac arrest, which is associated with electrical instability of the myocardium, ventricular arrhythmias. The development of a complication in the presence of an emergency medical team requires immediate resuscitation measures, including basic resuscitation measures and defibrillation.Aim: To present a clinical case of a patient with AMI with ST segment elevation complicated by recurrent ventricular fibrillation, hospitalized in an emergency hospital with the possibility of performing invasive interventions.Methodology and methods of research. The analysis of anamnesis, electrocardiographic data of the patient, the results of coronary angiography and stenting of the coronary artery, echocardiography examination, Holter monitoring, laboratory studies was carried out.Results. Patient P., female, 81 years old, was taken to the emergency hospital 2 hours and 15 minutes after the start of the clinic. At the prehospital stage, recurrent ventricular fibrillation, stopped by repeated three defibrillations. Non-contact, twice bouts of motor arousal. The council decided to conduct coronary angiography with possible stenting of the coronary arteries immediately. It was performed by femoral access on the right in 30 minutes after hospitalization. Complete occlusion of the anterior interventricular artery was revealed. Conductor recanalization and stenting of permanent residence was performed using a drug-coated stent. In the intensive care unit, drip administration of dopamine, noninvasive ventilation of the lungs, heparin administration were continued; double antiplatelet therapy, atorvastatin, amiodarone were prescribed. Since the fourth day, a beta-blocker has been added to therapy. Physical and psychological rehabilitation was carried out. She was discharged on the 15th day in a satisfactory condition.Conclusion. Out-of-hospital cardiac death requires urgent resuscitation measures, among which defibrillation occupies a special place, as well as immediate hospitalization to a cardiology center with the possibility of performing invasive  interventions. Early rehabilitation plays an important role in the treatment of patients.
Staffing, resource base of the healthcare system and population health in the Arkhangelsk region
Authors: Shelygin K. V.
Published: July 2023

The main purpose of the health care system is to maintain and improve the health of the population. Staffing is the main resource of the health care system, which allows to achieve the set goals and objectives. In this regard, it is of interest to identify the links between the human and resource capacity of health care and the level of population health, which can indicate the rationality of implementation of health-preserving technologies.Aim: To establish a link between the levels of resource and staff potential of the health care system and population health in the Arkhangelsk region over the period 2010–2020.Material and Methods. Population health indicators (incidence, life expectancy at birth, total fertility rate, infant mortality, maternal mortality) and health system indicators (availability of doctors, beds, capacity of outpatient clinics, number of nurses) were used as the material. Autocorrelation functions, cross-correlation functions, autoregressive integrated moving average were used to identify relationships.Results. Resource and staffing indicators have no significant correlation with population health levels in the Arkhangelsk region over the period 2010-2020.Conclusion. Our study found no significant links between indicators of the resource and staff capacity of the health care system and population health in the Arkhangelsk Region over the period 2010–2020, which may be due to the qualitative and quantitative characteristics of the data used.
Formation and assessment of medical competencies on a virtual model of the treatment and diagnostic process in cardiology
Authors: Karas S. I. , Arzhanik M. B. , Grakova E. V. , Balakhonova M. V.
Published: July 2023

Background. It is the competence of making diagnostic and therapeutic decisions that is the most important in clinical practice. Digital model of treatment and diagnostic process (TDP) allows provide the remote formation of skills for decision-making.Aim: To provide the methodological support of remote formation of competences, to improve and assess the skills of medical decision-making in cardiology.Methods. Clinical and diagnostic information from different sources was the material for creating virtual models of TDP. Skilled cardiologists were involved to develop technical specification; knowledge engineering methods were used. Fifty virtual patients with linear structure and ten with branched structure were developed. Technical specification was implemented using Web technologies – Java Script (framework Vue.js), Twitter bootstrap, PostgreSQL.Results. In the first phase of this project only a Web-resource was created. All digital models of patients’ TDP were placed in a linear order without any interactivity. To assess the effectiveness of medical decisions in the second phase of the project, branched TDP model with interactivity was created. It covers all stages of medical decision-making: from the patient hospital admission to his discharge. Besides the real invariant treatment of the patient, the model includes “subjunctive” process variants – “how could it be if ...” Among the interactive blocks, experts considered those leading to a change in TDP trajectory. We named them as “trigger” blocks, where the decisions influence upon TDP outcome. To assess the effectiveness of decisionmaking by learners, the rating system has been developed. It makes it possible to calculate not only general, but also particular personal ratings for certain categories of medical and diagnostic decisions.Conclusion. This study suggests the methodology for remote formation and evaluation of doctor’s competencies, which is implemented in the format of virtual TDP models.
Features of the management of elderly patients with non ST segment elevation myocardial infarction: analysis of risk factors, diagnosis and treatment strategy
Authors: Zaynobidinov Sh. Sh. , Khelimskii D. A. , Baranov A. A. , Gorgulko A. P. , Manukian S. N. , Naydenov R. A. , Krestyaninov O. V.
Published: July 2023

Despite the technological developments in the healthcare industry, cardiovascular disease mortality occupies a leading place among the structure of general mortality of the population. The use of modern treatment methods, especially, percutaneous coronary intervention, provides timely assistance to patients with acute coronary syndrome and helps to reduce mortality frequency. Currently, clear algorithms for the management of patients with ST-segment elevation myocardial infarction have been developed. However, despite it, there are paradigms in the management of patients with non-ST-segment elevation myocardial infarction (NSTEMI). This is primarily due to the fact that the vast majority of patients with NSTEMI are elderly and senile persons. This review article presented the main factors that adversely affect short- and long-term prognosis and results of clinical studies dedicated to the study of this problem.
Digital Transformation of Accounting in Industry 4.0 Perspective and an Empirical Study on Turkish Accounting Education
Authors: ÇETİN Ömer Orbay , BOZDOĞAN Tunga
Published: July 2023

Industry 4.0, with the unstoppable development of information technologies and the internet towards the end of the 20th century, is considered an industrial revolution that brings together digital technologies that are constantly increasing in number and variety. As a result of the increase in the use of digital technologies brought by the Industry 4.0, digital transformation, this topic has become increasingly important and begun to take place more in the literature. Studies examining the relationship between the Industry 4.0 and accounting are observed in the literature. However, there were not enough studies in the literature that measured the perspectives of students studying in the business administration departments towards the Industry 4.0 as well as their attitudes toward accounting courses. In this study, the effects of the Industry 4.0 on accounting and the digital transformation of accounting have been evaluated for business administration students. A total of 491 questionnaires were applied to the students of the department of business administration, and IBM SPSS Statistics 22 package program was employed for the reliability analysis of the data obtained from 491 questionnaires. Explanatory factor analysis was benefited to determine the validity of the scalesin the study. In the analysis, Kaiser-Meyer-Olkin (KMO) and Barlett Test were performed to measure the sample adequacy. According to the results of the analysis, it was revealed that there was a significant difference in the Industry 4.0 in terms of the views of the students studying in the e business administration department according to sex, age, academic year, and grade points average. In addition, it was also revealed that there was a significant difference in attitudes towards accounting courses and the Industry 4.0 among business administration students based on sex, age, academic year, and department.
Extracción de arabinoxilanos de subproductos agroindustriales adaptada a la estrategia universal de recuperación de compuestos bioactivos
Authors: Rodríguez-Viveros N. , Paz-Samaniego R. , Hernández-Hernández A.A. , García-Curiel L. , Pérez-Escalante E. , Contreras-López E. , Pérez-Flores J.G.
Published: July 2023

Los arabinoxilanos (AX) son polisacáridos de tipo hemicelulosa extraídos principalmente de cereales y subproductos agroindustriales. Están formados por una cadena de xilosas, con ramificaciones de arabinosa y otros azúcares. Además, pueden tener ácidos fenólicos como el ácido ferúlico esterificado que permite el entrecruzamiento de las cadenas y las posibles aplicaciones del polímero. Las características de los AX dependen de la fuente y el procedimiento de extracción por lo que en este trabajo se realizó una revisión de los métodos de extracción de AX partir de los subproductos de procesos agroindustriales, centrada en la estrategia universal de recuperación de compuestos bioactivos. Esta técnica se realiza en cinco etapas que van desde el nivel macroscópico al micromolecular para posteriormente aislar la sustancia bioactiva utilizando técnicas convencionales o emergentes, dependiendo de costos y beneficios en los procesos, así como de las características de la matriz. La muestra puede ser previamente tratada para facilitar la extracción. Existen otros métodos de extracción como extracción alcalina, la extracción ácida y extracción enzimática. La elección de la técnica de extracción es importante para lograr el máximo aprovechamiento y recuperación de los AX de subproductos agroindustriales, para aplicaciones en áreas como la industria alimentaria, cosmética y farmacéutica.
Desarrollo de un método de extracción por la técnica de MEPS para polifenoles en miel
Authors: Cobos Cervantes Paola , Armijo Martínez Samantha , Cavazos Rocha Norma , Paniagua Vega David , Portillo Castillo Omar J.
Published: July 2023

Se desarrolló y validó un método mediante la técnica de microextracción con sorbente empacado (MEPS) para la extracción de polifenoles en miel y su análisis mediante cromatografía de líquidos de alta resolución. El cartucho C18 resultó ser el más adecuado para la extracción simultánea de un mayor número de polifenoles, tales como ácido protocatechuico, ácido cafeico, ácido p-cumárico, ácido trans-ferúlico, ácido rosmarínico, quercetina, luteolina, apigenina y kaempferol. Para la optimización del volumen y tipo de disolvente en el paso de elución, se trabajó con un diseño de experimentos mediante el modelo D-Optimal, siendo 50 µL de metanol al 100 % la condición adecuada para la recuperación de los analitos. Bajo las condiciones seleccionadas como óptimas, el método resultó ser lineal, preciso y exacto con límites de detección y cuantificación de 0.039 hasta 0.071 μg/mL y de 0.131 hasta 0.238 μg/mL respectivamente. La aplicación del método se llevó a cabo mediante el análisis de una muestra de miel, el cual resultó ser preciso, encontrando factores de enriquecimiento de 2.64 y 2.86 para kaempferol y apigenina, respectivamente.
Estudio de los atributos fisicoquímicos de calidad que influyen en la vida útil de muffins de vainilla
Authors: Gálvez-Toledo D. K , Contreras-López E. , Jaimez-Ordaz J. , González-Olivares L. G. , Pérez-Flores J. G.
Published: July 2023

Un Muffin es un pastel pequeño redondo sin azúcar. En general, los productos panificados han sido objeto de diversas investigaciones debido a la interacción entre sus componentes y su deterioro. Puesto que en la presente investigación fueron estudiados unos muffins de vainilla con una buena estabilidad microbiológica gracias a los agentes conservantes utilizados en su formulación, el objetivo del presente trabajo fue determinar cuáles son los parámetros fisicoquímicos de calidad con la mayor influencia sobre su vida útil, utilizando el enfoque de pruebas aceleradas, con la finalidad de proponer estrategias para prolongarla. Para ello, los muffins fueron almacenados a diferentes temperaturas. Los cambios en el contenido de humedad, en la actividad acuosa y en el peso, fueron determinados por triplicado. Los resultados fueron ajustados con diferentes modelos matemáticos. La pérdida de peso fue la variable con mayor influencia sobre la vida útil del producto y la ecuación para una cinética de orden cero fue la que mejor describió los cambios (=0.817±0.308). En conclusión, el análisis cinético proporciona un criterio fiable para predecir la estabilidad y la vida útil de los muffins, con la información obtenida es posible establecer estrategias que permitan incrementarla.
Estudio computacional de la capacidad antioxidante de tuna (Opuntia Streptacantha)
Authors: Hernández-Méndez Diana , Fuentes-Ocampo Lucero , Diaz-Cervantes Erik
Published: July 2023

El presente proyecto está enfocado en evaluar de manera indirecta (empleando una peroxidasa) la capacidad antioxidante que existe en Opuntia Streptacantha mediante estudios in silico. Dicha especie posee compuestos fenólicos, de los cuales se evaluó su interacción con la proteína glutation peroxidase, la cual está involucrada en los procesos de oxidación, para observar el acoplamiento de los fitoquímicos y conocer su posible efectividad para retrasar los procesos de oxidación.
Evaluación de los compuestos bioactivos del aceite de romero (Rosmarinus officinalis L.) como conservador alternativo
Authors: Contreras-Hernández Isela , Castillo-Campohermoso Marco A. , Díaz-Cervantes Erik
Published: July 2023

En el presente trabajo se desarrolló la evaluación de algunos de los compuestos bioactivos del aceite esencial de romero (Rosmarinus officinalis L.), como una alternativa de conservación de alimentos. La evaluación de los compuestos se realizó con el software Molegro Virtual Doker. Se evaluaron los ligandos y el blanco biológico seleccionado (borneol desidrogenasa de la Salvia rosmarinus con NAD+ como cofactor) para determinar el efecto antioxidante y antimicrobiano que tienen los compuestos. Específicamente se estuvo trabajando con las moléculas de acetato de bornilo, ácido carnosico, ácido rosmarico, alcanfor, alfa-pineno y carnosol (fitoquímicos del romero), los cuales interactuaron con el blanco biológico que fue el borneol desidrogenasa de la Salvia rosmarinus. Se demostró que el acetato de bornilo tiene interacción más favorable, teniendo una eficiencia del ligando más negativa, respecto a los demás, -6.09 kcal/mol.
Idalia García. La vida privada de las bibliotecas: Rastros de colecciones Novohispanas (1700-1800)
Authors: Jiménez Pérez Isla Citlalli
Published: July 2023

Idalia García. La vida privada de las bibliotecas: Rastros de colecciones Novohispanas (1700-1800). Bogotá: Tierra Firme, Universidad del Rosario, Universidad Autónoma Metropolitana, 2020; 603.
Aguirre Salvador, Rodolfo; Enríquez, Lucrecia; Ramírez, Susan E. Los obispos y las reformas eclesiásticas en la América hispana borbónica
Authors: Mendoza Moo Elsy Anahí
Published: July 2023

Aguirre Salvador, Rodolfo; Enríquez, Lucrecia; Ramírez, Susan E. Los obispos y las reformas eclesiásticas en la América hispana borbónica. Ciudad de México: Universidad Nacional Autónoma de México, Instituto de Investigaciones sobre la Universidad y la Educación; 2022, 315 p. https://hdl.handle.net/20.500.12806/1400
Juan Camilo Galeano Ramírez. Curas en la diócesis de Popayán. La carrera eclesiástica y el regalismo borbónico, 1770-1808
Authors: Quintana Lantigua Patricia
Published: July 2023

Juan Camilo Galeano Ramírez. Curas en la diócesis de Popayán. La carrera eclesiástica y el regalismo borbónico, 1770-1808. Bogotá: Instituto Colombiano de Antropología e Historia ICANH, 2021, 152 pp. ISBN: 978-958-8852-94-2
Los Cantú. Sacerdotes y bienhechores del Nuevo Reino de León
Authors: Leyva Gutiérrez Nancy Selene
Published: July 2023

En la época virreinal las familias que quisieran contar con un descendiente sacerdote debían, además de patrocinar su formación, garantizar su sostenimiento. Con base en los protocolos notariales del Archivo Histórico de Monterrey y en las solicitudes de ordenación remitidas al obispado de Guadalajara se estudian las estrategias que realizaron estos grupos para sostener la educación de los jóvenes. En este trabajo se toma como estudio de caso la familia Cantú originaria del Nuevo Reino de León. Las mujeres de este clan familiar colaboraron no sólo en el incremento del prestigio familiar, estableciendo buenas alianzas matrimoniales y como patrocinadoras de las carreras de los jóvenes sacerdotes.
Narratives of Asexuality
Authors: Dambrowsky Hayle
Published: July 2023

In this paper, I utilize the lens of narrative power to argue that stories of asexuality have been employed to pathologize and separate people from heteronormative societies but can (and are) amplified to connect and mobilize people to resist dominant narratives and norms regarding sexuality. I apply this lens to two case studies. The historical and modern pathologizing of asexuality and the creation of online communities for asexual people and experiences. By exploring the power and hierarchy of narratives, I expose more people to non-normative sexualities and thus reduce the isolation and marginalization of asexual peoples and stories.
Transgender Ukrainians and the Need for LGBTQIA+ Inclusion in National and International Refugee Policies
Authors: Wachowich Annie
Published: July 2023

Over 7 million Ukrainians have become refugees since Russia's invasion of Ukraine. As a result, countries around the world have opened their doors and invited Ukrainians to seek refuge from the ongoing conflict. However, not all Ukrainians have experienced this conflict equally, with queer and transgender Ukrainians facing increased risks of gender-based violence, discrimination, and difficulties crossing borders due to inaccurate gender markers on their identification. This policy brief focuses on the unique challenges LGBTQIA+ Ukrainians have faced while fleeing the conflict. I provide an analysis of the persistent exclusion of LGBTQIA+ people within sexual and gender-based violence policies and refugee policies (like the Women, Peace and Security agenda and Feminist Foreign Policy initiatives) due to marginalization and systemic discrimination. This paper argues that the Government of Canada can address this issue, not just for Ukrainian refugees but for all refugees, by implementing LGBTQIA+ inclusive policies to address the gaps in Canada's current system. It should be noted, this policy brief examines the conflict from February 2022 to April 2022. Given that this is an ongoing conflict, some statistics may have changed, however, the lack of support for LGBTQIA+ refugees in national and international refugee policy remains a pressing issue.
Mannheim's "Problem of Generations" Applied"
Authors: Woodruff Rebecca
Published: July 2023

This paper seeks to analyze Karl Mannheim's generational approach to social history by applying it to the Boomer-led 1960s counterculture movement. This paper examines the extent and limitations of Mannheim's theory that generations can be a study of historical analysis by examining how race plays into generational cultural participation. This paper examines the Boomer's generational break from G.I and Silent Generation life and values in their dress, living conditions, and sexual practices. It also examines how race and the civil rights movement prohibited or dissuaded Black youth from participating in the counterculture movement. This paper analyzes to what extent generational study is useful in historiography when considering important variables such as race in cultural movements and participation.
Interrupting the Cycle of Sexual Violence
Authors: Kasim Amal
Published: July 2023

Alberta’s service landscape for sexual violence intervention in relation to youth exhibiting problem sexual behaviour (PSB) is noticeably lacking. “Current theories emphasize that the origins and maintenance of childhood [PSB] include sexual abuse as well as familial, social, economic, and developmental factors" (Friedrich et al., 2001; Friedrich, Davies, Feher, & Wright, 2003). Early intervention is critical and yet there are no services for these individuals to turn to. The current service landscape essentially requires youth to formally interact with the criminal justice system before they can be redirected to the necessary settings to address their behaviours. This paper highlights the need for non-punitive and judgement-free forms of preventative measures in order to disrupt the cycle of sexual violence.