bluuebunny/crossref_metadata_2025 huggingface dataset:
Double trouble-unveiling the hidden pain: bilateral paediatric parsonage-turner syndrome: an unprecedented encounter
Authors: Ganesh Arjun , Rajappa Srinivasan , Rajendiran Subashini
Published: October 2023

Parsonage-turner syndrome (PTS), also known as idiopathic brachial neuritis, is a rare disorder characterized by sudden-onset severe shoulder pain followed by weakness and atrophy of the shoulder and arm muscles. This case report presents the clinical scenario of an 11-year-old girl diagnosed with PTS, highlighting the unique challenges and considerations in the paediatric population. In our case, a 11-year-old girl presented with sudden-onset severe bilateral shoulder pain, followed by weakness and atrophy of the shoulder and upper arm muscles. The clinical examination revealed muscle wasting and limited range of motion. The diagnosis of PTS was confirmed through MRI and electromyography (EMG) showing denervation in the affected shoulder muscles. Patient was managed with symptomatic supportive treatment in the form of analgesics and physical therapy. Patient is on the road to recovery and on regular follow up. We concluded that prompt recognition and appropriate management of PTS are crucial to optimize outcomes and prevent long-term disability, particularly in the paediatric population.
Floating knee with early onset fat embolism: a case report
Authors: K. Selva Kumar , Deva  , Thirunthaiyan
Published: October 2023

Fat embolism syndrome in young adults is most commonly associated with the long bone fractures most commonly femur and tibia. Its concomitance with floating knee is reported scarcely in reviewing the literature. Though it has been proposed that onset of fat embolism presents following an asymptomatic interval for about 24 to 72 hours, our patient developed onset within 8 hours following trauma. This case report is of first in this kind ever reported in the literature. We present a caseof 26 year old male patientwith floating knee Fraser type1 and Early Onset Fat Embolism syndrome who developed within 8 hours ofinjury underwent staged intramedullary nailing of femur and tibia with an excellent functional outcome without any sequelae of fat embolismat 2 year postoperative followup. Appropriate clinical judgement and awareness to suspect fat embolism syndrome and timely immobilisation with proper supportive care and serial reassessment and planned surgery preferably intramedullary nailing in young patient would benefit the patient in toto in case of floating knee with early onset fat embolism.
Tubercular cold abscess: uncommon location of a common disease
Authors: Jindal Parth , Hashmat Ahmer , Srivastava D. C.
Published: October 2023

Musculoskeletal tuberculosis is not rare to find, but presence of the disease and such extensive involvement at an unusual site without much of bone involvement is rare. Reporting a case of isolated cold abscess in a 60-year-old male with evening rise of temperature, weight loss and diffuse swelling in his leg involving almost entire anterior aspect of leg. Magnetic resonance imaging (MRI) was advised to investigate further and revealed large focal intra medullary heterogenous collection and large lobulated juxtacortical collection in tibialis anterior muscle. Hematoma/organised abscess, incision and drainage was done and sent for Z-N staining which showed acid-fast bacilli. Anti-tubercular treatment was administered- isoniazid (H), rifampicin (R), ethambutol (E), pyrazinamide (Z). Outcome was favourable and patient become symptomatic better. Drainage of the cold abscess and antitubercular coverage produced good results in this rare presentation of tuberculosis.
How to avoid knee tunnel convergence when performing a combined anterior cruciate ligament reconstruction and lateral extraarticular tenodesis utilizing the antero medial window
Authors: Espiritu Wesson Pious A. , Sanchez Melissa Mae R.
Published: October 2023

The anterolateral structures of the knee have been demonstrated to have a significant impact on reducing rotational instability and the forces applied to the anterior cruciate ligament reconstruction (ACL) graft after surgical reconstruction. Combined ACL reconstruction and lateral extraarticular tenodesis are being performed at an increasing number due to its promising outcome in properly indicated patients. However, tunnel convergence in combined ACLR and lateral extraarticular tenodesis can lead to graft damage and possible failure defeating the purpose of this very effective technique. This technical note describes how to avoid knee tunnel convergence when performing a combined ACL reconstruction with lateral extraarticular tenodesis utilizing the “Antero medial window”.
INTERPELAÇÃO DAS MULHERES INDÍGENAS SOBRE A CONSERVAÇÃO DE SEUS TERRITÓRIOS
Authors: Ayres Ariadne Dall'acqua , Daniza Jagso Kaingang Jozileia , Neres Vanessa Fe Ha , Da Rocha Brando Fernanda
Published: October 2023

O aumento das crises socioambientais no mundo exige a compreensão dos povos indígenas e de seu conhecimento para combatê-los. As mulheres indígenas têm apresentado seus corpos-territórios como parte crucial para conservação da natureza, pois a relação entre corpo e território sob sua perspectiva é diferente. Assim, ideias e iniciativas do movimento de mulheres indígenas para proteger seus territórios, corpos-territórios-espíritos e a natureza são apresentadas. Resultados dessas iniciativas se expressam em engajamentos coletivos dentro e fora de suas terras, resistindo para garantir seu estilo de vida e bem-estar, denunciando a falta de direitos e os episódios de violência. Divulgar e potencializar as iniciativas locais e globais do movimento indígena para proteger seu corpo-território e natureza das crises ambientais por meio do engajamento coletivo é essencial em todo o mundo. Mulheres indígenas organizam-se e promovem ideias a partir de sua compreensão sobre a relação ser humano-natureza e da importância de ações imediatas.
PAPEL SOCIAL DA COSMOLOGIA MACUXI PARA A COMUNIDADE CAMARARÉM - RAPOSA SERRA DO SOL
Authors: Campos Luana Cristina da Silva , Silva Maques Elder
Published: October 2023

O distanciamento às fontes orais de pesquisa nas ciências humanas, proporcionado por uma herança positivista, limitou por anos as análises pautadas em mitos, contos e histórias como elementos normatizadores da organização de alguns povos. Nesse sentido, o presente artigo busca trazer uma reflexão sobre as potencialidades da cosmologia Macuxi, através da análise do seu papel social e histórico. Para tanto, foi utilizado parte das informações apresentadas na dissertação defendida por Elder Silva Marques, com o título “Anna Pantoni Eseru - As Formas de Compreensão e Preservação dos Sítios Arqueológicos em Comunidades Indígenas: um estudo de caso sobre a Comunidade Camararém, Terra Indígena Makuxi, Roraima – Brasil”. O presente artigo buscou um aprofundamento dos dados coletados para a dissertação, tais como entrevistas e relatos de vivência, para, a partir da hermenêutica de base historicista, identificar quais componentes da mitologia Macuxi reverbera fatos da história da comunidade Camararém – Raposa Serra do Sol.
RIOS, PONTES E ULTRAPASSAGENS
Authors: Herbetta Alexandre , Valle Pineda Eleazar
Published: October 2023

Este texto busca indicar potencialidades presentes no campo da literatura indígena no Brasil e no México, enquanto política intercultural para todos – indígenas e não indígenas. Por meio de atividades desenvolvidas no âmbito do Curso de Educação Intercultural no Núcleo Takinahaky de Formação Superior Indígena (NTFSI) da Universidade Federal de Goiás (UFG), da leitura de escritos e reflexões indígenas acerca da literatura produzida e de uma análise de políticas interculturais em ambos países, relacionamos a produção literária, de base comunitária, com a potencialidade de políticas educativas que tratem da diferença, as quais buscam a formação de pessoas aptas para uma convivência equilibrada, justa e pacífica.
Hoja de ruta para la transformación digital del sector energético en América Latina y el Caribe
Authors: Alvarez Alonso Oliverio , Díaz Echeverría Alberto , Afonso Noé , Sánchez Campos Alfonso , Bordiu Garcia-Ovies Cecilia , Irigoyen José , Riobó Alexander , Boeck Daza Eric , Pfeifer Maria
Published: October 2023

La transformación digital del sector energético en América Latina y el Caribe es un proceso profundo que va más allá de la tecnología. Implica actualizar activos, sistemas y cultura organizativa. Esta transformació es impulsada por cuatro pilares: participación de los usuarios, flexibilidad en los sistemas de generación, resiliencia y una cadena de valor sólida. La publicación identifica lecciones aprendidas y mejores prácticas a nivel mundial y mide el grado de avance en la región a través de encuestas. Por último identifica cinco recomendaciones para acelerar la transformación digital del sector en la región: un marco regulatorio moderno y estable, incentivos económicos para invertir en digitalización, adopción de tecnologías disruptivas, una cultura digital fuerte y colaboración público-privada.
Hybrid Algorithm of Backpropagation and Relevance Vector Machine with Radial Basis Function Kernel for Hydro-Climatological Data Prediction
Authors: Syaharuddin  , Fatmawati  , Suprajitno Herry , Ibrahim
Published: October 2023

Hydro-climatological data serves a pivotal role in monitoring climatic alterations and facilitating agricultural planning, inclusive of evapotranspiration estimation, water management, and crop pattern design. The necessity to accurately and expeditiously model and forecast this data underscores the need for effective methodologies. This paper introduces a hybrid algorithm, integrating backpropagation and relevance vector machine (BP-RVM) with a radial basis function (RBF) kernel. A comparative analysis was conducted between RBF and Logsig activation functions in conjunction with resilient backpropagation (trainrp) and Levenberg-Marquardt backpropagation (trainlm). The algorithm was employed to predict and categorize rainfall, temperature, wind speed, humidity, and sunshine duration data. Through extensive trials, the architecture parameters in the training-testing process of the BP-RVM algorithm were meticulously determined. Mean squared error (MSE) and mean absolute percentage error (MAPE) values were classified as indicating high forecast accuracy (<10%). Despite the RBF-trainlm kernel function combination exhibiting a faster epoch completion rate, the BP-RVM algorithm with the RBF-trainrp kernel function combination is recommended for future data prediction stages due to its lower error generation. The BP-RVM-RBF-trainrp algorithm outperformed BP-RVM-RBF-trainlm, with an average error difference of 1.39% in the training process and 2.28% in the testing process. The identified algorithms and architectures present potential for future applications in evapotranspiration calculation and crop pattern planning based on hydro-climatological data.
Artesanato, design e sempre-vivas em Diamantina/MG
Authors: Mourão Nadja Maria
Published: October 2023

Na região de Diamantina/MG, as comunidades e grupos de apanhadoras de flores sempre-vivas, são detentoras de um modo de vida e conhecimentos relacionados ao bioma nativo e seu manejo. Este projeto busca desenvolver possibilidades de produção artesanal, por meio de ações sustentáveis e criativas, com foco na cadeia de valor das flores sempre-vivas coletadas na Serra do Espinhaço. Após a revisão bibliográfica, em pesquisa qualitativa, foi proposto uma metodologia de cocriação, com as representantes das comunidades locais, sob as bases do design social. No território brasileiro são encontradas, aproximadamente, 630 espécies de sempre-vivas, quase a metade das espécies registradas em todo planeta. A maior quantidade das espécies ornamentais, colhidas na região, destina-se ao mercado externo por meio de atravessadores. Durante as atividades coletivas, foi desenvolvida uma linha de produtos que preservam a identidade local. Este modelo de iniciativa em projeto social, agrega valores territoriais aos produtos e promovem a sustentabilidade.
Cinema e universidade: tecendo reflexões e diálogos
Authors: Brasil Evelyn do Anjos , Andrade Aldair Oliveira de
Published: October 2023

Nos últimos anos no Brasil, as escolas e instituições de pesquisa têm direcionado seus esforços para a incorporação de novas tecnologias visando aprimorar a eficácia da interação entre ensino e aprendizagem. Esta atividade teve como objetivo principal utilizar o cinema como instrumento de reflexão sobre questões políticas, culturais, filosóficas e educacionais da atualidade na formação dos discentes do ICSEZ/UFAM. Sua implementação se deu por meio de oficinas de preparação e de execução. Foram realizados diversos encontros de estudos e reflexão com a equipe de execução como primeira fase, e como segunda fase, quatro sessões de exibição, debate e reflexão sobre as temáticas que emergiram das produções cinematográficas selecionadas. Pode-se afirmar como resultado significativo da atividade que esta proporcionou a construção de um olhar crítico dos participantes sobre o mundo concreto e a experiência fílmica. De modo geral acredita-se que o projeto alcançou seus objetivos, a despeito das dificuldades de sua realização, à medida que possibilitou uma experiência concreta de construção de nova postura diante de uma produção cinematográfica.
¿Qué puede aportar la enseñanza de la historia a la deslegitimación de la violencia y a la construcción de la paz en Euskadi? (How can the teaching of history help discredit violence and build peace in the Basque Country?)
Authors: Bermudez Angela ,   Universidad de Deusto, Sáez de la Fuente Izaskun ,   Universidad de Deusto, Bilbao Galo
Published: October 2023

"¿Qué puede aportar la enseñanza de la historia a la deslegitimación de la violencia y a la construcción de la paz en Euskadi?" presenta las conclusiones y recomendaciones derivadas del proceso de investigación llevado a cabo en el marco de la Comunidad de Aprendizaje sobre Memoria, educación histórica y construcción de la paz en Euskadi. El objetivo es estimular el diálogo abierto y la exploración crítica sobre la enseñanza de la historia del pasado violento a las nuevas generaciones y su potencial para contribuir a la deslegitimación de la violencia y a la construcción de paz. // "How can the teaching of history help discredit violence and build peace in the Basque Country?" presents the conclusions and recommendations that resulted from the research process developed within the Learning Community on Memory, History Education and Peace Building in the Basque Country. The goal is to encourage open dialog and critical exploration of the ways in which teaching new generations about violent pasts may contribute to discrediting violence and building peace.
Analiza chemostratygraficzna różnowiekowych osadów budujących górotwór karpacki
Authors:   Instytut Nafty i Gazu – Państwowy Instytut Badawczy, Kowalska Sylwia
Published: October 2023

"Artykuł prezentuje próbę przeprowadzenia analizy chemostratygraficznej dla różnowiekowych skał budujących górotwór karpacki. W pierwszej kolejności zdecydowano się stworzyć syntetyczny profil geologiczny dla osadów występujących we wschodniej części polskich Karpat. Wykorzystane próbki, w większości piaskowce, pochodziły z głównych poziomów stratygraficznych w obrębie jednostek skolskiej i śląskiej, gdzie zidentyfikowano skały od dolnej kredy po paleocen. Ze względu na dostępność materiału badawczego do badań wytypowano próbki o udokumentowanej stratygrafii z dwóch otworów, D-1 i H-1, zwracając głównie uwagę na ich klasyfikację stratygraficzną. Następnie dla porównania wykonano profil chemostratygraficzny dla otworu Kuźmina-1. Stwierdzono obecność bardzo dużego zróżnicowania składu chemicznego pomiędzy głównymi poziomami stratygraficznymi wyróżnianymi na podstawie badań paleontologicznych w badanych otworach, co pozwoliło wyznaczać zdecydowane granice pomiędzy poszczególnymi poziomami stratygraficznymi. Możliwość stworzenia unikalnych modeli chemostratygraficznych dla czterech analizowanych poziomów stratygraficznych: kredy górnej – senonu (warstwy inoceramowe), kredy górnej / paleocenu (warstwy istebniańskie), eocenu (warstwy pstre) oraz oligocenu (warstwy krośnieńskie) potwierdziło również wykonanie diagramu klasyfikacyjnego Herrona. Największe zróżnicowanie cech chemostratygraficznych uzyskano w przypadku utworów kredowych. Wstępnie badania wykonano w laboratorium akredytowanym Actlabs, tak aby móc później przeprowadzić ewaluację wyników uzyskanych za pomocą przenośnych spektrometrów (pXRF Titan, o zakresie pomiarowym od Mg do U, oraz pXRF Tracer, który umożliwia również pomiar zawartości Na, oba aparaty firmy Bruker). Potwierdzono, że wyraźne zróżnicowanie zawartości poszczególnych pierwiastków widoczne jest zarówno dla pierwiastków głównych, jak i śladowych. Pierwiastki najbardziej diagnostyczne to Na, Mg, Fe, K, Ca, również Si, choć w tym przypadku zakres zmienności jest nieco mniejszy. W przypadku pierwiastków śladowych są to S, P, Mn, Ti, Sr, Zr, Ba, Rb i Zn, które można również analizować za pomocą przenośnych spektrometrów pXRF. Wykonane porównanie wyników składu chemicznego uzyskiwanych przenośnym spektrometrem pXRF oraz w laboratorium Actlabs wykazało, że możliwe jest wykorzystanie na większą skalę samych pomiarów spektrometrem pXRF. Dla większości pierwiastków diagnostycznych uzyskano wystarczająco precyzyjne wyniki przy wykorzystaniu przenośnych spektrometrów pXRF.
Drilling fluids in complicated conditions: a review
Authors:   Azerbaijan State Oil and Industry University, Shmoncheva Yelena Y. , Jabbarova Gullu V. ,   Azerbaijan State Oil and Industry University, Abdulmutalibov Timur E. ,   Azerbaijan State Oil and Industry University
Published: October 2023

The review in this article focuses on various aspects of drilling extended reach (ERD) wells. Reaching extreme depths and setting world records for deviation illustrates the importance of well design and operating strategies. Studies of articles describing various locations, including Sakhalin Island in Russia and offshore Vietnam, provide insight into ERD operations. Furthermore, the challenges of drilling in specific geological conditions, such as layered sandstones and reactive clay, are considered. Particular attention is paid to issues related to wellbore instability and drilling fluid optimization. The results of technical studies highlight the key role of maintaining wellbore stability in achieving successful ERD results. The articles emphasize the importance of understanding geomechanical factors, employing optimal mud weight, lubrication, and specialized drilling fluids to counteract instability. It demonstrates that maintaining appropriate mud weights and employing specific drilling techniques are crucial for mitigating instability-related issues. The integration of mechanical and chemical approaches is advocated for effectively managing shale-related instability. The utilization of innovative materials and fluid systems is central to the successful resolution of stability-related problems. The incorporation of micronized sealing polymers in conjunction with conventional plugging materials is detailed as an effective approach to counter wellbore instability. The synergistic combination of materials, additives and mud salinity is showcased to achieve effective shale stabilization and optimize drilling time. The authors emphasize the importance of selecting the optimal composition for each well based on experience and laboratory testing and present laboratory-tested solutions that have been successfully applied in field operations. In summary, these articles collectively offer insights into a range of strategies to combat wellbore instability. They cover the use of advanced materials, innovative fluid systems, and chemical approaches to maintain wellbore stability, improve drilling efficiency, and reduce nonproductive time.
Wykorzystanie możliwości rozwoju międzynarodowego – przykład Grupy Kapitałowej „Sokołów” SA
Authors: Janiuk Ireneusz , Jarosiński Mirosław
Published: October 2023

liwości rozwoju międzynarodowego przedsiębiorstw: rozwój etapowy i wczesną internacjonalizację. Wyniki badań na temat internacjonalizacji polskich przedsiębiorstw pokazują wzrost zainteresowania polskich przedsiębiorstw obiema ścieżkami rozwoju. Prezentowane w artykule przedsiębiorstwo, Grupa Kapitałowa „Sokołów” SA, jest dobrym przykładem rozwoju etapowego na rynkach międzynarodowych, a jednocześnie typowym przykładem internacjonalizacji przedsiębiorstw przemysłu mięsnego w Polsce, którego rola w polskim eksporcie dynamicznie rośnie.
Metaphorical Visual Imagery from the Perspective of Children
Authors: Wiśniewska-Kin Monika
Published: October 2023

This paper will present the results of a study of an educational project on visual metaphors in children’s initiated discourse. The purpose of the study was to identify children’s metaphorical skills in recognizing similarities and noticing differences between the target domain and the source domain of visual metaphor in Iwona Chmielewska’s artistic picture book Two People, dedicated to the issue of community. In the designed didactic intervention activities, the research material came from participant observation, focus interviews and analysis of children’s creations (graphic visualizations). The research was carried out with a group of third-graders in selected elementary schools, in a metropolitan environment. The results of the research show children’s preferences for translating one area of metaphor by another, as well as strategies for constructing children’s knowledge about life in the community. In addition, they point to the need to expand the educational environment in Polish educational culture.
The Experience of Participating in the Digital Community as the Essence of Children’s Everyday Life. Research Report
Authors: Dziekońska Joanna
Published: October 2023

The article discusses the research aimed at revealing the meanings that children give to their daily participation in the digital community. For several decades, the immersion of children in the online world has been evoking different opinions of adults – from those very enthusiastic to those highly alarmist. However, it seems to be essential to listen to the voice of the children themselves. This creates an opportunity to rise above the level of assessing the impact of media on children and to reach the space that hide a repertoire of colorful experiences related to the presence of children in the online world. For this purpose, children aged 8–10 took part in the focus interviews. The research material was collected and analyzed according to Virginia Braun and Victoria Clarke’s six-stage analytical framework. One of the most important conclusions is that online activity fills children’s everyday life to a large extent and their online presence is naturally intertwined with being offline. Children perceive the internet as a source of many opportunities and declare that they feel safe, as they are aware of the rules that must be followed in it. The Internet provides them space where they can be together and engage in many activities. Children appreciate the value of face-to-face contacts, which they find different from those mediated by technology.
Preschool as a Shared Place. About the Fundamental Values of the University Preschool in Gdansk
Authors: Kmita-Zaniewska Katarzyna , Maj Aleksandra
Published: October 2023

The article consists of two parts. In the first part, we introduce the premises of the educational philosophy of Reggio Emilia, which formed the basis for the concept of the University Preschool in Gdansk. We refer to the values that, from the perspective of adults who are part of the preschool community, were the foundation for creating everyday educational context in the University Preschool during the first three years of its functioning. In the discourse of Reggio Emilia, a preschool is not perceived so much as a place of instruction or formation, but rather as a place of education, a place where values are transmitted, discussed and constructed. Democracy, participation and subjectivity are key categories on which the narrative is focused. In the second part, these categories are the starting point for reconstructing the cultural practices present in the everyday life of the preschool which fulfill the above mentioned values. We refer to the goals of the University Preschool, the principles and conditions of its functioning. We also describe solutions, especially in the field of the organization of the educational environment, which contribute to the building of a community in which children are listened to and supported by adults.
Gamification needs analysis in learning at the University
Authors: Kristanto Andi , Ramdhani Sendi , Susilana Rudi , Hasyim Nurhikmah , Dewi Laksmi , Rejekiningsih Triana
Published: October 2023

This study aims to look at the needs in the field related to the development of gamification in learning in universities. These innovations must be implemented immediately to infuse learning activities with new life. This qualitative descriptive study was conducted using a survey method between January and March 2021. A questionnaire was utilized for data collection. The questionnaire sheets were used to collect data about university courses. The descriptive and qualitative analyses of the research data were conducted. The study enrolled 100 students from Universitas Terbuka, Universitas Pendidikan Indonesia, Universitas Sebelas Maret, Universitas Negeri Surabaya, and Universitas Negeri Makassar. Based on the findings of the investigation carried out, it can be seen that gamification is very much needed in learning at the university level. Gamification in higher education is critically needed and must be implemented in practice. The next step needed is to develop gamification-based learning for universities.
Keywords: Digital technology; gamification; learning; need analysis; university
Comparing student perceptions of in-class, online synchronous, and online asynchronous instruction
Authors: Palvia Shailendra , Matta Vic
Published: October 2023

This article compares the efficacy of undergraduate teaching for in-class, online synchronous, and online asynchronous modes of instruction with implications for adapting the modes of instruction in computer information processing. The study uses a repeated measures design with pairwise comparisons while controlling for instructor, students, and course content across these modes of instruction. The study examines the following six perceptions held by students:  instructional aspects such as instructor facilitation, student-to-student interaction, instructor-to-student interaction, course design, learning outcomes, and student satisfaction. The study also examines actual student performance on homework, quizzes, and exams. All findings were interesting and insightful. Student perceptions of almost all instructional aspects were significantly higher for the in-class mode than the two online modes of instruction. However, actual student performance was significantly better for online modes of instruction. The discussion section triangulates these statistical results with a review of 3000+ open-ended student responses to explain results, provide guidelines, and suggest future research.
Keywords: Asynchronous instruction; distance education; E-learning; in-class; online; synchronous instruction
СОДЕРЖАНИЕ МАРГАНЦА, ЦИНКА И МЕДИ В ГРУДНОМ СБОРЕ № 4 И ЕГО НАСТОЯХ
Authors:   Первый Московский государственный медицинский университет имени И.М. Сеченова (Сеченовский Университет), Гравель И.В. , Рак Е.И. ,   Первый Московский государственный медицинский университет имени И.М. Сеченова (Сеченовский Университет), Попова Е.Н. ,   Первый Московский государственный медицинский университет имени И.М. Сеченова (Сеченовский Университет), Лёвушкин Д.В. ,   Первый Московский государственный медицинский университет имени И.М. Сеченова (Сеченовский Университет)
Published: October 2023

Актуальность. В растениях марганец, цинк и медь находятся в биологически доступных формах, которые легко усваиваются при приеме лекарственных растительных препаратов. Однако лекарственные растительные препараты не рассматриваются как источник минеральных веществ. Цель исследования – изучение содержания марганца, цинка и меди в грудном сборе № 4 и его компонентах, реализуемых в Российской Федерации. Материалы и методы. Объект исследования – грудной сбор № 4 производства ОАО «Красногорсклек-средства», а также его компоненты: ромашки аптечной цветки, календулы лекарственной цветки, мяты перечной листья, багульника болотного побеги, солодки корни, фиалки трава. Содержание элементов в лекарственном растительном сырье и в настоях из него измеряли методом атомно-эмиссионной спектрометрии. Результаты. Установлено, что в грудном сборе № 4 содержание исследуемых микроэлементов варьировало в диапазоне 8,59–282,14 мг/кг, переход в водные извлечения составил 33,6–44,8%. Переход микроэлементов из сбора в настой оказался выше, чем из отдельных компонентов. Возможное суточное поступление марганца, цинка и меди с водным извлечением составило 23,26±2,06; 0,80±0,06; 2,28±0,18 мг/сут соответственно. Выводы. Исследование показало, что грудной сбор № 4 можно рассматривать как дополнительный источник марганца, цинка и меди.
Physical exercise-intervention can be valuable therapy for COVID-19 confinement and post-COVID-19 periods
Authors: Kwak Yi-Sub , Han Kiyun , Lee Jaeeun , Kim Jongnam
Published: October 2023

[Purpose] The COVID-19 pandemic and its transition into an endemic phase have profoundly impacted physical health, well-being, mental health, education, and various aspects of society, including the economy and social networks. Home confinement, social distancing, and physical inactivity have exacerbated numerous health issues, including obesity, diabetes mellitus, hypertension, hyperlipidemia, cardiovascular diseases, depression, and poor sleep quality. A systematic review has revealed significant findings: Regular aerobic programs (such as cycling or walking at an intensity of 60–80% of HR max for 20–60 minutes per session, repeated 2–3 times a week) have proven effective in improving both physical and mental health, as well as immune function. This type of physical activity has been shown to increase immunological markers, including lymphocytes, leukocytes, neutrophils, monocytes, and interleukin-6 (IL-6), while reducing low-grade inflammation. Therefore, in this study we aimed to assess the impact of tailored exercise interventions on the physical and mental health of COVID-19 patients. Based on the results, we can establish exercise intervention strategies to mitigate the negative health consequences during and after the COVID-19 pandemic.[Methods] We conducted a search of the PubMed database from January 2020 to August 2023 using predefined search terms such as “COVID-19 and post-COVID-19,” “exercise intervention and immunity,” and “mental health.” By examining references, we explored the links between exercise interventions and the mental and physical health of COVID-19 patients.[Results] A tailored, multifaceted exercise intervention should be developed and implemented to address the existing mental challenges and enhance mental health during both the pandemic and the post-COVID-19 periods.[Conclusion] Breathing exercises and respiratory support techniques, including yoga, thoracic expansion exercises, airway clearance methods, and breathing control, are likely to be beneficial.
Katı Kültür Fermantasyonu: Hayvan Beslemede Güncel Biyoteknolojik Uygulamalar
Authors: Ghorbel Roukaya , Koşum Nedim
Published: October 2023

Dünya çapında artan nüfus ile birlikte hayvansal gıdalara (et, süt ve yumurta gibi) talep de artmaktadır.
Dolayısıyla hayvansal üretim verimliliğinin artırılmasında yeni ve verimli stratejilerin uygulanması önem
taşımaktadır. Geleneksel hayvancılık ıslah yöntemleri, şu anki üretimi sürdüremez; bu yüzden, üretkenliği
artırmak için biyoteknoloji dahil olmak üzere yeni yoğun ve güncel tekniklere ihtiyaç duyulmaktadır. Yem
fiyatları, çiftçilik sistemlerinin karşılaştığı en önemli kısıtlamalardan biridir. Fiyat dalgalanmaları ve sürekli
artan yem fiyatları nedeniyle beslenme uzmanları, yerel yem kaynaklarından yararlanmak için alternatif
biyoteknolojik uygulamalara dikkat çekmiştir. Bu sınırlamaları kaldırmak için, katı kültür fermantasyonu (KKF) harika bir biyoteknolojik çözüm olarak bildirilmiştir. Aslında besin biyo-yararlanımını artırmak, bağırsak patojenik bakterilerini sınırlamak ve yem kaynaklarında anti-besin faktörlerini azaltmak için kullanılmaktadır. Bu makale, biyoteknolojinin güncel uygulamalarından biri ‘Katı Kültür Fermantasyonu’na odaklanarak, hayvan besleme ve yem teknolojisinde biyoteknolojinin önemini göstermeyi amaçlamaktadır
Nonviral cryoglobulinemic vasculitis: an updated review for clinical practice
Authors: Núñez-Conde Andrea , Rodríguez-Pintó Ignasi , Alba-Garibay David A. , Álvarez-Abella Alba , Jerez-Lienas Alba , Llargués Oriol , Alba-Sánchez M. Antonio , Oleas Diana , Alba Marco A.
Published: October 2023

The clinical spectrum of cryoglobulinemic-associated diseases is broad and heterogeneous, with manifestations ranging from mild symptoms (e.g., isolated palpable purpura) to organ- and life-threatening involvement (e.g., membranoproliferative glomerulonephritis). Cryoglobulins are classified into three types. Type I cryoglobulinemia consists of one monoclonal immunoglobulin (Ig) and is practically always associated with B-cell lymphoproliferative disorders. In contrast, type II/III (mixed) cryoglobulinemia is composed of mono- or polyclonal IgM with rheumatoid factor activity bound to polyclonal IgG. Since the introduction of more efficient therapies for chronic hepatitis C virus (HCV), other diseases such as systemic autoimmune disorders and lymphoproliferative neoplasms have been established as the main causes of mixed cryoglobulinemic vasculitis. The pathogenesis of cryoglobulinemic vasculitis is a complex multifactorial process that involves B-cell aberrant lymphoproliferation and autoantibody production. Therefore, treatment of these patients may involve not only measures aimed to mitigate the severity of clinical manifestation but also those that address the associated underlying disease responsible for Ig production. The treatment of patients with type I cryoglobulinemia is primarily focused on controlling B lymphocyte clones responsible for cryoglobulin production, mostly with chemotherapy drugs. Treatment of mixed cryoglobulinemia syndrome is based on rituximab plus glucocorticoids, which induces remission in the vast majority of cases. In the rare patients that do not respond to rituximab administration, potential rescue approaches include alkylating agents, biologic therapies, conventional immunosuppression, and plasma exchange, although with partial efficacy. This narrative review explores the etiology, pathophysiology, clinical manifestations, treatment, and prognosis of nonviral cryoglobulinemic disease. A special focus is placed on the treatment of type I cryoglobulinemia and rituximab-resistant non-HCV cryoglobulinemic vasculitis.
From slope seismic resilience to regional road network resilience: an integrated framework for evaluating the seismic resilience of mountainous road networks
Authors: Xiong Min , Hu Hongqiang , Huang Yu
Published: October 2023

A systematic review was conducted, ranging from the seismic resilience of single slope engineering structures as disaster-bearing bodies to their transformation into disaster-inducing bodies owing to seismic dynamic instability. The resilience of slopes is considered with regard to regional transportation networks, which are most severely threatened by earthquake-induced landslide disasters. For the engineering structure of a single slope as a disaster-bearing body, the stage before the slope engineering loses stability can be considered as the first stage of slope seismic resilience evaluation. This review summarizes the latest progress in seismic resilience evaluation and reinforcement design from the perspective of engineering seismic resilience. In response to the lack of definition for the resilience of existing regional road networks to earthquake-induced landslide impacts during the review, the second stage involves the transformation of the seismic dynamic instability of regional slopes into landslide disasters; resilience is defined as the global system reliability of the regional road network in this study. From the perspective of network reliability, an assessment framework for the resilience of the regional transportation network against seismic landslide disasters is systematically proposed in this study. In accordance with high-dimensional nonlinear network dynamics theory, this paper highlights the future research direction of introducing high-dimensional network dynamics theory into the disaster resilience of regional road networks affected by landslide disasters.
TATALAKASANA TERKINI HIPERTENSI PULMONER PADA ANAK
Authors: Koentartiwi Dyahris , Ramadhanti Ardhanis , Chafid Ervan Aditya Putra
Published: October 2023

Hipertensi pulmoner (HP) merupakan suatu kondisi dimana terjadi peningkatan tekanan vaskular paru yang berkaitan dengan berbagai etiologi. Pada anak, sekitar 50% HP seringkali ditemukan pada pasien dengan penyakit jantung bawaan dengan left-to-right shunt, penyakit pulmonal, gangguan perkembangan paru serta idiopatik. Insiden HP pada anak secara umum dilaporkan sebesar 4-10 kasus per 1 juta anak per tahun. Terapi koreksi secara operatif atau kateterisasi masih menjadi pilihan utama untuk koreksi HP. Namun tingkat morbiditas dan mortalitas paska koreksi dilaporkan cukup tinggi. Oleh karena itu, beberapa studi terus mengkaji dan mengembangkan pilihan terapi untuk HP. Beberapa diantaranya adalah terapi vasodilator dengan PDE-5, CCB, analog prostasiklin dan inhalasi NO. Karena etiologi yang sangat komplek dan belum banyak bukti klinis atau konsensus tentang tatalaksana HP pada anak, maka pemilihan terapi HP yang sesuai masih cukup sulit. Pada prinsipnya tujuan utama dari terapi HP adalah meningkatkan angka harapan hidup dan memfasilitasi pasien agar dapat melakukan aktivitas secara mandiri tanpa limitasi. Tujuan dari penulisan tinjauan kepustakaan ini adalah untuk membahas tentang tatalaksana terkini HP pada anak sehingga diharapkan dapat menambah pengetahuan dan referensi sebagai dasar praktis klnis tentang tatalaksana HP pada anak. Kata Kunci: Penyakit Jantung Bawaan, Hipertensi Pulmoner, Anak, Left-to-right Shunt, Vasodilator Pulmonary hypertension (PH) is a condition in which pulmonary vascular pressure increases and associated with diverse diseases or etiology.  In children, 50% of PAH cases are caused by CHD, especially due to large left-to-right shunts. Another causes were developmental lung diseases and idiopatic PH. The estimated incidence of sustained PH in all categories was reported at 4–10 cases per million children per year. Corrective procedures by surgery or catheterization are the therapies of choice for reversible PH. Since morbidity and mortality due to PAH after correction is high, many recent studies have been done on the evaluation in treatment option of PH. Several vasodilator therapy including sildenafil (Phosphodiesterase type 5 inhibitor), Calcium Channel Blocker, Prostacyclin Analogs and Nitric Oxide were recommendation therapy. Various etiologies and lack of consensus make it difficulty in management of PH. The ultimate goal of treatment should be improved survival and to facilitate normal activities of childhood without self-limitation. Therefore, this review was aimed to discuss about recent management of PH in children.
Effectiveness of Using Graphics Interchange Format (GIF) in Teaching Chemistry
Authors: Abgao Jules Mark
Published: October 2023

The study utilized a quasi-experimental method of the pretest-posttest design with pre-selected groupings for the control and experimental groups. The study used validated researcher-constructed questionnaires to determine the student’s performance during the experimentation. A pretest was implemented for both groups prior to the implementation of the proposed interventions, with the experimental group exposed to online lectures with GIF-Enhanced Instructional Materials, while the control group utilized conventional online lectures. After the implementation of both interventions, a posttest was administered, and an attitude survey toward Chemistry. The findings showed that both groups had a significant improvement in terms of their performance from the pretest to the posttest, but the significant difference between the mean gains of both groups favored the experimental group. The experimental group was positive about the use of GIF in teaching Chemistry, while the control group somewhat agreed on the positive impact of Chemistry, while the experimental group agreed. In conclusion, using GIFs in online lectures proved to be more effective and impactful than conventional online lectures.
Experimental Analysis of the Effect of Water-Cement Ratio on the Performance of Manufactured Sand Concrete
Authors: Hu Wenjun , Liu Pingyun , Zhang Han , Li Kun , Yin Wenhao , Xue Yi , Han Yutong , Wang Peisen
Published: October 2023

Manufactured sand and natural sand have great differences in terms of physical properties, chemical composition, and so on. In the mix ratio design of manufactured sand concrete, the traditional common concrete ratio cannot be used. The water-cement ratio playing a crucial role in the mix ratio design. The optimum water-cement ratio can not only improve concrete performance, it can also reduce cement consumption and costs. The present study examines the working performance indicators and mechanical performance indicators of manufactured sand concrete using Fujian granite with three strength grades (C35, C40 and C50) at different water-cement ratios. The impact of water-cement ratio on the operational and mechanical performance of manufactured sand concrete with different strength grades is analyzed and summarized. Revised sentence: The findings suggest that the workability of Fujian granite concrete is directly influenced by the water-cement ratio. Additionally, the water-cement ratio indirectly affects the mechanical properties of manufactured sand concrete. Finally, when changing the water-cement ratio, cube compressive strength, splitting tensile strength and bending strength exhibit similar trends. The optimal water-cement ratio for C35 concrete is determined to be 0.39, considering the workability and mechanical properties of Fujian granite manufactured sand concrete. Similarly, the optimal water-cement ratio for C40 concrete is 0.34, while for C50 concrete it is 0.32.
Rare Cranial Osteopathy in a Northern Bottlenose Whale (Hyperoodon ampullatus) Stranded in Rhode Island, Northwest Atlantic, in the 19th Century
Authors: Anné Jennifer , Van Bressem Marie-Francoise , Van Waerebeek Koen
Published: October 2023

Few reports exist on the pathologies of the northern bottlenose whale (Hyperoodon ampullatus) and other Ziphiidae. We here describe a large exostosis in the right pterygoid bone of adult female H. ampullatus ANSP-3004 that stranded on the US Atlantic coast in 1867. Images of the skull and 14 cranial measurements were examined and compared with two ‘normal’ adult female H. ampullatus specimens. Surface scans of ANSP-3004 were made with a Faro Design Arm 1.0 scanner at 75µm resolution. The form, structure and width (15.9 cm) of the right pterygoid were found to be abnormal. Its distal extremity was curved in labial direction while its proximal extremity was deformed by a large, bulbous exostosis of 14.3 x 12.5 cm that partially obstructed the right nasal passage. Lytic lesions in the posterior end of the exostosis exposed deep resorption lacunae. The left pterygoid was thin (3.4 cm) and laterally displaced. No diagnosis was possible for lack of histological examination but the osteopathy was consistent with osteoma, a benign bone tumor commonly seen on the jaws and nasal sinuses of bovines, phylogenetical relatives of Cetacea. The partial nasal passage obstruction may have affected respiration to some degree, but since the female was lactating, general fitness appeared stable.
HYPERTRIGLYCERIDEMIA AND ATHEROSCLEROTIC CARDIOVASCULAR DISEASES
Authors:   City Clinical Hospital No. 7, Kazan, NURIEVA LUIZA M. , KIM ZULFIYA F. ,   City Clinical Hospital No. 7, Kazan, GALYVICH ALBERT S. ,   Kazan State Medical University, SADYKOVA DINARA I. ,   Kazan State Medical University
Published: October 2023

Introduction. Elevated triglyceride levels are associated with an increased risk of cardiovascular disease. An increase in the concentration of triglycerides indicates an elevated level of atherogenic lipoproteins, such as very low density lipoproteins, very low density lipoproteins residues and chylomicron residues. Lipoproteins rich in triglycerides increase the formation of foam cells, which is one of the key stages of the pathogenesis of atherosclerosis. Aim. To analyze the results of modern studies on elevated triglycerides and cardiovascular diseases. Material and methods. A review of medical literature and current research for the period from 1965 to 2022, published in the databases eLibrary, Google Scholar, PubMed, devoted to the analysis of hypertriglyceridemia and its effect on atherosclerotic cardiovascular diseases by the keywords «hypertriglyceridemia», «cardiovascular diseases», «atherosclerosis». Results and discussion. According to the Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation study, an elevated level of triglyceride was found in 30.2±0.52% of men in the entire sample, which is significantly higher than in women (20.1±0.34%; p<0.0001). According to the largest epidemiological study (Framingham Study), a TG level of more than 1.7 mmol/l means a significantly higher risk of developing cardiovascular complications. A prospective study by The Prospective Cardiovascular Munster (PROCAM) showed that an increase in the concentration of triglycerides from 2.3 mmol/l to 9.00 mmol/l increases the risk of cardiovascular diseases., even after correction of other risk factors. Conclusion. Triglycerides play an important role in the development of atherosclerotic diseases of the cardiovascular system, regardless of the etiology of hypertriglyceridemia. And effective lipid-lowering therapy prescribed in time can increase the life expectancy of such patients
SATISFACTION WITH THE WORK OF GENERAL PRACTITIONERS AND SURGEONS IN PUBLIC AND PRIVATE MEDICAL ORGANIZATIONS
Authors:   Peoples’ Friendship University of Russia (RUDN University), SHUKUROV MURAT R. , KONOVALOV OLEG E. ,   Peoples’ Friendship University of Russia (RUDN University), SHULAEV ALEXEY V. ,   Kazan State Medical University
Published: October 2023

Introduction. Job satisfaction has a significant impact on the commitment of the staff of a medical organization and their motivation to work. Aim. To study satisfaction with the work of therapeutic and surgical doctors in medical organizations of various forms of ownership. Material and methods. With the help of a specially designed questionnaire, a sociological survey of 404 therapeutic and surgical doctors working in public and private medical organizations in the city of Voronezh was conducted. Results and discussion. According to the results of the survey, 78.0% of the doctors who participated in the study were completely or partially satisfied with their work, 4.7% were not satisfied at all, and 5.8% of the respondents found it difficult to answer. Doctors of public and private polyclinics are more often dissatisfied with their work than those working in hospitals. In addition, doctors of private medical organizations, both inpatient and outpatient, more often gave an overall positive assessment of satisfaction. In most cases, the reasons for job dissatisfaction were insufficient wages, somewhat less often an uncomfortable work schedule, low equipment of a medical organization and the level of work organization. Conclusion. The revealed features of satisfaction with the work of various gender and age groups of therapeutic and surgical doctors in medical organizations of various forms of ownership should be taken into account by management in the formation of personnel policy and corporate culture. Keywords: doctors, specialty, type of medical organization, work, satisfaction.