bluuebunny/crossref_metadata_2025 huggingface dataset:
Effect of preservative solutions on postharvest of Eustoma Grandiflorum floral stems during refrigerated storage
Authors: Höhn Daniela , Peil Roberta Marins Nogueira , Grolli Paulo Roberto , Perin Lais , Da Rosa Douglas Schulz Bergmann
Published: December 2023

Preservative solutions contribute to flowers post-harvest quality and longevity, having different effects according to the species, cultivar, cold storage period and the solution composition. This work aimed to determine the preservative solution more effective on opening flower and longevity on flower cut stems of E. grandiflorum, submitted to two cold storage periods. The experiment was arranged in a 2x4x10 factorial, with two storage periods, five and ten days; four preservative solutions, water (100%); sodium hypochlorite (25 ml L-1) + sucrose (10%); aluminum sulfate (250 mg L-1) + sucrose (10%); and silver nitrate (50 mg L-1) + sucrose (10%); and ten evaluation dates. Cut stems from the cultivar ‘White Excalibur’ were placed taken to cold storage for 5 and 10 days at 5°C and 78% of relative humidity. After cold storage, the stems were distributed to glass pots containing different preservative solutions. Every two days, visual evaluations were performed, verifying the opening flower and longevity. An illustrative scale were used to assess the opening of flowers buds, with grades ranging from 1 to 5. For the longevity, the number of days that flowers remained viable in the preservative solutions until the disposal was considered. The cold storage periods do not affect opening flower and longevity of ‘White Excalibur’ floral stems. Silver nitrate + sucrose and aluminum sulfate + sucrose were the preservative solutions that provides better post-harvest quality and longevity, with higher opening flowers and extended viability.
INVESTIGATION OF TECHNOLOGICAL CAPABILITIES OF DEFORMATION CUTTING METHOD FOR THE INNER SURFACE ENHANCING OF HEAT EXCHANGE TUBES
Authors: Zubkov Nikolai
Published: December 2023

The analysis of existing methods of surface enhancing for in-tube intensification of heat-exchange processes is presented. Approved variants of using the method of deformational cutting for the increasing the inner surface of heat-exchange tubes are proposed, including principles, schemes of realization, designs of tools and attachments. Photos of macrostructured surfaces and heat exchange intensifiers obtained inside the tubes to increase the efficiency of convective, condensing and boiling heat transfer is presented.
REGULARITIES OF VIBRATION MECHANOCHEMICAL CLEANING OF PARTS FROM OPERATIONAL CONTAMINATIONS UNDER THE CONDITIONS OF RENOVATION PRODUCTIO
Authors: Lebedev Valeriy , Pastukhov Philip , Chaava Mihail
Published: December 2023

The technological possibilities of using vibration processing for mechanochemical cleaning of the surfaces of parts in the conditions of renovation production are considered. A diagram of vibration processing is presented that ensures the technological effect of the cleaning process at the stage of preparatory operations, and dependencies for their determination are proposed. The basic principles of vibration mechanochemical cleaning of parts have been established. It has been shown that the effectiveness of the process of removing contaminants from the surface depends on the type of process fluid, the activating shock-pulse effect of abrasive granules on it and their granulometric characteristics.
EXPERIMENTAL STUDIES ON THE COMBINED PROCESS OF ELECTROCHEMICAL MECHANICAL POLISHING
Authors: Perova Alla , Boldyrev Aleksandr , Boldyrev Alexander , Grigorash Vladimir , Padurets Anna
Published: December 2023

This article presents the results of experimental studies of the electrochemical mechanical polishing process, which combines anodic dissolution, possessing high localizing properties, with the dynamic effects of abrasive grains. The essence of the combined process is described, when, under the influence of operating voltage, a continuous electrochemical dissolution of the treated surface occurs with the formation of oxide films on it, followed by their removal together with the treated metal by means of abrasive grains quasi-fixed in the polishing pad. The description and conditions of the conducted experiments are given. The influence of the weight content of the abrasive in the composition of the electrolyte-abrasive mixture on the removal of metal and the roughness of the treated surface is shown. The impact on the course of the combined process of the frequency of rotation of the polishing pad and the pressure of the workpiece on it is noted. At optimal values of the studied parameters, electrochemical-mechanical polishing makes it possible to ensure high geometric quality of the treated surface and high process productivity.
PROBLEMS AND PROSPECTS FOR THE DEVELOPMENT OF THE BACKUP NETWORK OF TRANSPORT AND LOGISTICS INFRASTRUCTURE OF THE NORTHERN DELIVERY IN THE REPUBLIC OF SAKHA (YAKUTIA)
Authors: Iovleva Elizaveta , Timofeev Nurgustan
Published: December 2023

The transport and logistics infrastructure of the northern delivery of the Republic of Sakha (Yakutia) is one of the key components in the development of this region. Northern delivery is a system for organizing the transportation of goods in the taiga, sparsely populated areas and incomplete road network. This article will analyze the existing problems of northern delivery in Yakutia, and also propose recommendations for optimizing the transport and logistics infrastructure.
DETERMINATION OF THE CURRENT TECHNICAL CONDITION OF VEHICLE TRANSMISSION UNITS BY MEANS OF VIBRATION DIAGNOSTICS DURING TEST RUNS ON THE ROAD SPECIAL STAGE
Authors: Leliovsky Konstantin , Molev Yuri
Published: December 2023

The transmission of a car is considered as a diagnostic object in this article. Significant diagnostic signs for the designated purposes are indirect (acoustic, vibrational, thermal, etc.). From the practice of operation, it is known that the vibrations that occur during the operation of a technically serviceable node, transmission unit, differ from the vibrations that occur during the operation of a failed node, as well as from a node that is in a pre-failure state. It is obvious that as the resource is exhausted, the spectral composition of the vibrations transmitted by the transmission units to the external environment changes. Consequently, by changing the spectral composition of vibrations, we have the opportunity to track the change in the technical condition of the mechanical unit from its serviceable condition up to its failure (node failure). Hardware, this can be done using built-in vehicle design, or external, specially installed vibration sensors.
Erprobung des interkommunalen Radverkehrsmanagements (IRVM) im NUDAFA-Reallabor für interkommunale Radverkehrsförderung – Chancen und Grenzen der Verstetigung
Authors: Samland Ute , Kollert Christoph , Ahrend Christine
Published: December 2023

Das NUDAFA-Reallabor hat mit dem Interkommunalen Radverkehrsmanagement (IRVM) in der Kommunalverwaltung in Eichwalde eine Schnittstelle zwischen Forschung und Praxis geschaffen: Das IRVM ist als Realexperiment konzipiert, in dem innovative Ansätze der interkommunalen Zusammenarbeit erprobt und dabei auch überfällige Radverkehrsprojekte in die Umsetzung gebracht werden. Die innovative und gleichzeitig sehr praktische Konstruktion des Realexperimentes könnte als Vorlage zur Verstetigung und als Vorbild für weitere Reallabore dienen. In diesem Beitrag sollen Möglichkeiten und Grenzen dieser Konstellation beleuchtet werden.
Rahmenkonzept zur Geschäftsmodellentwicklung autonomer Logistics-as-a-Service (LaaS)-Lösungen – Der ländliche Raum als Reallabor
Authors: Hausladen Iris , Kirchgeorg-Muradyan Lyuzi , Böckler Liss , Schmischke Christian
Published: December 2023

Das Projekt myLOG MOL testet autonome Liefersysteme im Reallabor. Im ländlichen Raum nutzen lokale EinzelhändlerInnen ein gemeinsames Logistics-as-a-Service-Konzept, um ihre digitalisierten Produktangebote taggleich an KundInnen zu liefern. Diese Publikation stellt ein Rahmenkonzept für die Geschäftsmodellentwicklung autonomer Logistics-as-a-Service-Lösungen vor. Basierend auf dem Business Model Canvas werden Aspekte der Digitalisierung des Produktsortiments im stationären Einzelhandel, betrieblicher und rechtlicher Rahmen sowie infrastrukturelle Anforderungen untersucht.
Pengenalan Objek Museum dengan Teknologi NFC pada Android dan RFID (Studi Kasus Pada Museum Jawa Tengah Ranggawarsita)
Authors: Fuadi Zaki , Sutikno Sutikno
Published: December 2023

Museum Jawa Tengah Ranggawarsita adalah salah satu tempat yang memiliki banyak koleksi objek bersejarah. Objek-objek bersejarah tersebut memiliki informasi penting di dalamnya. Informasi bisa berupa sejarah bangsa atau peradaban penting yang ada di Indonesia. Namun pada kenyataannya informasi mengenai objek bersejarah yang ditampilkan masih kurang jelas, detail dan informatif. Hal ini karena banyaknya informasi dari objek yang perlu ditampilkan dan dikenali oleh petugas kajian museum. Administrasi objek-objek museum juga masih menggunakan cara manual yaitu menggunakan arsip fisik untuk setiap informasi objek yang ada. Diperlukan sebuah sistem untuk mempermudah proses administrasi dan penampilan informasi objek dengan mengenali objek. Pengenalan objek menggunakan Near Field Communication pada android smartphone dan tag pasif Radio Frequency Identification dapat menjadi solusi dari permasalahan ini. Untuk pengunjung, sistem dapat digunakan untuk mengenali objek yang diinginkan dan menampilkan informasi objek secara detail, jelas dan informatif, sedangkan untuk petugas museum sistem dapat digunakan untuk administrasi objek-objek museum yang ada. Sistem dikembangkan dengan menggunakan proses pengembangan perangkat lunak unified process dalam satu iterasi. Sistem memanfaatkan web-service untuk sebagai penyedia atau perantara data sistem. Sistem sudah melewati pengujian black-box dan white-box dengan hasil lulus uji. Sistem diharapkan dapat mempermudah proses pengenalan objek museum dan administrasi objek museum.
Investigasi Efek Partial Shading Terhadap Daya Keluaran Sel Surya
Authors: Aprillia Bandiyah Sri , Zulfahmi Muhammad Rafiqy , Rizal Achmad
Published: December 2023

Energi listrik pembangkit tenaga surya yang terhubung ke jaringan terpadu bergantung pada intensitas radiasi matahari. Namun, pada beberapa area pembangkit tenaga surya masih terdapat pohon dan gedung disekitar nya yang dapat menutupi sebagian area permukaan panel surya (partial shading). Penelitian ini bertujuan untuk investigasi efek dari variabilitas radiasi matahari akibat partial shading terhadap daya keluaran sel surya 1 Wp. Berdasarkan hasil observasi pada pengujian pukul 10.00 â€“ 14.00, tegangan terbuka dan arus hubung singkat pada sel surya mengalami penurunan seiring kenaikan intensitas partial shading. Semakin besar partial shading pada sel surya maka daya keluaran yang dihasilkan semakin rendah.  Efek setengah partial shading dari total area sel surya mengakibatkan penurunan daya sebesar 88.2%. Seperempat shading mengakibatkan penurunan daya keluaran sel surya sebesar 75.6% dibandingkan daya pada kondisi normal. Selain itu Kenaikan suhu sel surya mengakibatkan penurunan tegangan terbuka yang cukup berarti.
ОСВІТНІ ВИКЛИКИ ТА ІННОВАЦІЇ У ВИЩІЙ ПЕДАГОГІЧНІЙ ОСВІТІ УКРАЇНИ: ВІД ДЕСТРУКТИВНИХ НАСЛІДКІВ ВІЙНИ ДО ЕФЕКТИВНОГО ЗМІШАНОГО НАВЧАННЯ
Authors: Котун Кирил , Баніт Ольга , Радомський Ігор
Published: December 2023

Війна принесла істотні зміни в освітній процес, вимагаючи швидкої адаптації та розробки нових підходів до навчання. У статті основна увага приділяється виявленню ключових деструктивних наслідків війни для вищої педагогічної освіти на основі аналізу сучасного стану змішаного навчання в закладах вищої педагогічної освіти України, в умовах війни. Детально окреслено ключові деструктивні наслідки війни для вищої педагогічної освіти на трьох рівнях: на загальнодержавному, на рівні закладів вищої освіти, на рівні учасників освітнього процесу, із врахуванням трьох компонентів (психологічного, методичного, технологічного). Автори обґрунтовують різні шляхи максимізації ефективності психологічних, методичних і технологічних ресурсів, що відіграють ключову роль у забезпеченні якості змішаного навчання в умовах війни. Ці шляхи будуть цінними особливо для розробки різних стратегій та інструментів для підтримки викладачів у реалізації ефективних змішаних моделей навчання, а також адаптації навчальних матеріалів та методик до умов обмеженого доступу до ресурсів та зміненого освітнього середовища. Важливого значення набуває розробка та апробування технології максимізації ресурсів змішаного навчання для забезпечення теоретичної і практичної підготовки викладача-супервізора закладу вищої педагогічної освіти з урахуванням теоретичного обґрунтування шляхів максимізації ефективності психологічних, методичних і технологічних ресурсів змішаного навчання у воєнний час та повоєнного відновлення України. В цілому, автори статті пропонують комплексний погляд на проблематику змішаного навчання в умовах війни, висвітлюючи ключові виклики та пропонуючи ефективні рішення для їх подолання, що має важливе значення для розвитку освітньої сфери в сучасних умовах.
Innovative Swallowing Rehabilitation Balloon and Its Impact on Swallowing Outcomes in Home-Based Stroke Cases in Taiwan: Study Protocol for Randomized Controlled Trial
Authors: Chen Nai-Ching , Lin Yu-Ru , Chou Yi , Chen Huei-Yu , Lee Yao-Lin , Weng Jui-Yu , Kuo Jinn-Run
Published: December 2023

We outlined a randomized controlled trial assessing the effect of a novel swallowing rehabilitation balloon on post-stroke dysphagia in home-based care. Stroke often causes dysphagia, and standard rehabilitation methods have limitations, prompting the need for innovative interventions. Stroke-induced dysphagia is challenging as it requires improved interventions beyond current limitations. The effect of the swallowing balloon’s impact on aspiration efficiency was assessed in and risk of the trial with stroke patients. Patient satisfaction, compliance, and cost-effectiveness were also evaluated. The outcome showed better swallowing and reduced risk of aspiration were achieved. This indicated the effectiveness of home-based balloon therapy. This novel approach enhances post-stroke dysphagia rehab, improves patients’ health, and reduces healthcare costs.
“Paul Celan/ Parisian Elegy”, or: a Western Route to the East. An Approach to ‘Conceptual Genetics’
Authors:   Università di Siena, Miscoli Miriam
Published: December 2023

This essay aims to reconstruct the conceptual history of the origin and suppression of the so-called “Parisian Elegy”, a cycle of poems which Celan planned to include in his No One’s Rose until just a few months before publication (1963). The poet conceived the idea of composing an independent cycle as the closure and peak of the entire collection after he wrote the Valaisian Elegy, a long poem which articulates the arduous search for one’s self through memory and in sorrow. For the outcast poet living in Paris, this search takes on geographical and linguistic contours, as it emerges from the fourth part of No One’s Rose, conceptually and genetically in-terwoven with “Parisian Elegy”. Following the methodological path of the ‘Conceptual Genet-ics’, opened in 2010 by Axel Gellhaus, this work tries to demonstrate how deep this cycle inter-acts with the final cyclic conception of the volume and in which way it seems to predicate a relational and topographical conscience of grief.
A STUDY OF EXPRESSION OF P53 IN PREMALIGNANT AND MALIGNANT LESIONS OF UTERINE CERVIX
Authors: B. Rathod Kalpana , S. Gajbhiye Sudeshna , A. Nakate Leena , Jadhav Shweta
Published: December 2023

Carcinoma of the uterine cervix is one of the leading causes of mortality in women worldwide(1,2). There are primary and secondary biomarkers in
cervical carcinoma. The primary marker being HPV DNA and secondary markers like p53, c-fos, p50, fra 1, p16, notch 1, rb and telomerase. The
secondary marker p53 has been found to be helping in differentiating neoplastic from non-neoplastic and CIN lesions in various studies(3). Thus, it
may be used as a marker of prognostication for the patients with cervical lesions(4). The current study was aimed to analyze p53 expression in
malignant and premalignant epithelial lesions of the uterine cervix and to correlate p53 expression with histological types and grades of carcinoma
cervix. Out of 60 cases included in this study, p53 positivity was observed in 85% of the cases, excluding CIN-II and CIN-III. CIS and invasive SCC
exhibited positive p53 expression. Higher tumor stages showed increased p53 expression. Statistically signicant associations were found between
p53 positivity and microscopic type, clinical stage, and grade of cervical carcinoma. Further studies with larger sample sizes and patient follow-up
are warranted to investigate the correlation of p53 expression with clinicopathological parameters. Such research could facilitate the development
of p53-targeted therapy for cervical carcinoma.
PROGNOSTIC FACTORS AFFECTING SURGICAL OUTCOME IN DECOMPRESSIVE CRANIECTOMY IN SEVERE HEAD INJURY
Authors: Gopal Nn , Patil Raviraj , Kumar Singh Amit , Anand Dubey Saurabh , Solanki Prakshi
Published: December 2023

Introduction Intracranial hypertension occurring after traumatic brain injury (TBI) as a delayed secondary pathologic process initiated at the
moment of injury. These lead to a vicious cycle whereby reduced cerebral perfusion pressure (CPP) causes reduction of cerebral blood ow (CBF)
and oxygenation, with worsening of brain edema and, eventually, brain herniation, and death. decompressive craniectomy (DC), a procedure
consisting on removal of part of the skull and opening of the underlying dura, can be used as a last-tier therapy to mitigate ICP elevation.
Aims And Objectives:
Ÿ Effect of duration for hospitalisation and time lapse before surgery and hospital stay.
Ÿ GCS Score at time of presentation, before and after surgery and at discharge.
Ÿ Post op complications- meningitis, osteomyelitis, epilepsy, surgical site infection, neurological decits
Materials And Methods: Inclusion criteria: observational study, conducted in a tertiary care institute, collecting data over a period of 1 year.
GCS ≤ 8. Patients with raised Intracranial pressure with associated Intracranial lesions (SAIH, SDH, CONTUSION etc), Midline shift > 5mm
Exclusion criteria:Patients with severe co-morbid injuries involving other organs (Polytrauma). Patients with severe co-morbid medical
disorders. Inability to understand and give consent. Participants who might not be able to comply with the study procedures till the end of the study.
Firearm Injury. Results And Conclusions A total of 42 patients aged 5-65 years of age (mean age 43.46±13.75 years) admitted Mean GCS at
admission was 5.38±1.28 (Range 3-8). Mean duration of hospital stay was 11.40±5.50 days (Range: 3-22 days). At discharge, only 4 (8.0%)
patients achieved score 5 (Good response to treatment) on Glasgow Outcome scale (GOS). 15 (35.7%) expired (GOS 1), 5 (11.9%) were in
vegetative state (GOS 2), 8 (19.0%) were severely disabled (GOS 3), and 10 (23.8%) were moderately disabled (GOS 4). Patients with GOS 1 & 2
were classied as Poor outcome (n=20; 47.6%), GOS 3 & 4 were classied as Fair outcome (n=18; 42.9%), and with GOS 5 (n=4; 9.5%) were
classied as Good outcome. %). Signicant association between unconsciousness at presentation and outcome was observed.Patients with poor
outcome presented with signicantly lower GCS and had less duration of hospital stay.
A STUDY ON DOSIMETRIC COMPARISON OF THREE DIMENSIONAL CONFORMAL THERAPY AND VOLUMETRIC MODULATED ARC THERAPY IN LOCALLY ADVANCED RECTALCANCER.
Authors: Anam Hassan Syeda , Kumari Chinta. Sanjeeva , Taskeen Syeda Iqra
Published: December 2023

Neoadjuvant Chemo Radio Therapy followed by surgery is the standard of care for locally advanced Rectal carcinoma. Traditionally Radiotherapy
is given by using conventional AP/PA elds. This was associated with small bowel toxicity as. Advent of Multi Leaf Collimetor (MLC) had paved
way for conformal techniques to reduce the bowel doses with promising results. Newer technologies like Intensity Modulated Radio Therapy (
IMRT) and Volumetric Moulated Arc Therapy (VMAT) have shown to further improve the dose conformity to target and signicantly reduce dose
to normal tissues as shown by studies in Head and Neck and Prostate cancers. In this study,we attempt to compare this dosimetric properties like
target coverage and normal tissue doses between plan using 3DCRT and VMAT. We hypothesis that VMAT will have better target conformity and
better normal tissue sparing.
DAY-4 LILLE SCORE AS PREDICTOR OF RESPONSE TO CORTICOSTEROIDS AND SHORT TERM MORTALITY IN SEVERE ALCOHOLIC HEPATITIS.
Authors: Kripal P S , Ravishankar T , Selvan V Arul , Vadivu A Senthil
Published: December 2023

Background: Alcoholic hepatitis (AH) is a clinical condition with high mortality rates. Maddrey's Discriminant function (MDF) is a commonly
used prognostic score for patients with AH with a DF score ≥ 32 is classied as severe alcoholic hepatitis (sAH). Corticosteroids is still the
mainstay of treatment for Patients with sAH, demonstrating modest improvement in survival at 28 days corticosteroid therapy has been associated
with increased risk of infections in patients with sAH. We evaluated whether the use of the Lille Model at day 4 (LM4) is useful to predict response
to corticosteroids and short term mortality at 28 days as compared with conventional Lille score at day 7 (LM7). A Materials And Method
Prospective observational study was performed, and all consecutive patients with AH admitted over a one year period were observed. Relevant lab
data was utilised to assess baseline severity assessment scores (MDF,MELD,ABIC.GASH) . Patients with sAH as evidenced by MDF > 32 without
contraindications to corticosteroids were treated as per standard protocol with corticosteroids . Patients receiving corticosteroid therapy were
assessed with LM 4 scores at day 4 of treatment and LM7 Scores at day 7 of treatment , all patients receiving steroids where continued on therapy till
day 7 before a decision on withdrawal if LM7 >0.45,28-day mortality was assessed in all patients . Prediction of response to corticosteroid therapy
was assessed by LM4 and LM7 scores and compared. A total of 62 patients w Results ere admitted with AH during the study period of I year, 48
(77.4%) of these patients had SAH as evidenced by MDF >32, of the patients with sAH 34/48 (70.8 %) were eligible for steroid therapy. The short
term mortality at 28 days was observed in 6 /62 (0.96%) patients, all of whom had sAH and 2 were non responders to corticosteroid therapy and 4
were ineligible to steroid therapy. There was no difference between the proportion of patients with a responder LM4 versus LM7 (28% vs. 35%, p =
0.30). 92.0% of patients were correctly identied as responders or not by LM4 compared with LM7. LM4 has comparable accuracy Conclusion
with LM7 in predicting response to corticosteroids, and 28- mortality in patients with sAH. Assessing the efcacy of corticosteroids at an earlier
time point using LM4 scores may help avoid a more prolonged futile use of steroid therapy and help reduce complications associated with
prolonged steroid use in sAH.
TO STUDY THE CORELATION OF IRON DEFICIENCY ANAEMIA WITH GLYCOSYLATED HEMOGLOBIN (HBA1C) IN PATIENTS OF DIABETES MELLITUS TYPE II.
Authors: Upadhyay Monika , Mane Mahadeo
Published: December 2023

Background: Over the past few decades there is an increase in the prevalence of diabetes mellitus (DM) and is associated with a number of
complications. Glycosylated Haemoglobin (HbA1c) is used as the “gold standard” for measuring the glycaemic control and is also used as
predictor of diabetic complications. As per WHO, iron deciency is the commonest out of all deciency diseases worldwide. Anaemia is cited
as a major confounding factor in the measurement of HbA1c. It was shown by few studies that patients with iron deciency had higher HbA1c
levels while few demonstrated that absolute HbA1c levels and mean HbA1c levels were lower in patients with iron deciency anaemia. All
these studies gave contradictory and inconsistent results. Thus this study is conducted to know the effect of iron deciency anaemia on
glycosylated haemoglobin levels in diabetic individuals. 1.To study the correlation of iron deciency Aims and Objectives: anaemia with
glycosylated haemoglobin (HbA1c) in patients of diabetes mellitus type II. 2.To know the correlation between RBC parameters and
glycosylated haemoglobin (HbA1c). A total of 104 k Materials and Methods: nown cases of diabetes mellitus type II diagnosed or follow up
with HbA1c > 6.4% having anaemia were taken for the study after Institutional ethical clearance was obtained from the Institutional Ethics
Committee on Human Subjects Research, Dr. D.Y Patil Medical College Hospital and Research Institute, Kolhapur. In this research, Results:
a total of 100 patients were allocated to the study group. The study population's average age was 53.76 years. In the study population, the
average Hb level was 9.32 gm/dl. From the Karl Pearson's product moment correlation coefcient (r) between haemoglobin and HbA1c, the r
and p value were 0.3766 & 0.0077 respectively which is highly signicant thus justifying a signicant negative correlation between the two
parameters. The mean HbA1c of the study group was 10.04. In individuals with iron decient anaemia, Conclusion: Hb and HbA1c exhibited
a statistically signicant negative connection.
NEAR-PEER TEACHING METHODS FOR IMPROVING BASIC SURGICAL SKILLS OF INDIAN MEDICAL GRADUATES – A CONTROLLED COMPARATIVE STUDY
Authors: Gaikwad Kiran , Dhabarde Madhuri , Ghorpade Nilesh , Belekar Dnyanesh
Published: December 2023

Background: Near-peer teaching (NPT) is a TLMethodology where the trainer is one or more academic years senior than the person being trained.
There are very few publications that studied NPTs effectiveness although the literature agrees on the benets of NPTmethod. Our study was aimed
at evaluating effectiveness of NPTin the training of basic surgical skills. Methods: 100 Final M.B.B.S students were divided in 4 equal batches of
25 students in each batch and each batch participated in surgical skills course .All batches completed the same curriculum. Two batches were
trained by NPT tutor ( Fresh Medical Graduates i.e. Interns ) and remaining two batches were trained by senior faculty members. Pre and post
course tests were taken which were supervised and evaluated by senior faculty. Test results were analysed and students feedback obtained by online
questionnaire. Results: In students group trained by NPT tutor performance improved with completion of the course (median total marks scored
increased from 23.5 to 41.5 marks p< 0.01). While students group trained by faculty members (median total marks scored increased from 22.5 to
42.5 marks p < 0.01). Students feedback on overall satisfaction for NPT tutor group was 4.5 and for faculty trained group was 4.8 on a scale of 5.
Conclusions: Near-peer teaching is equally effective in basic surgical skills training as a conventional faculty assisted training.
A RARE CASE OF PROTEIN C AND S DEFICIENCY IN A CASE OF BAD OBSTETRIC HISTORY WITH SUCCESSFUL PREGNANCY OUTCOME
Authors: Agrawal Aishwarya , Gupta Prerna , HB Aishwarya , Mestri Saylee , Mehendale Madhuri , Sarmalkar Meenal
Published: December 2023

Abortions are very common in the rst and second trimesters of pregnancy, and thrombophilia can be a contributing factor. Protein C and S
deciency are rare, inherited or acquired disorders that can increase the risk of thrombophilia. These women particularly, have a higher risk of
developing blood clots in the placental blood vessels leading to placental insufciency and, ultimately, to grave fetal complications. This is a case
report of the successful management of a case of bad obstetric history in a diagnosed case of Protein C and S deciency with the use of adequate
antepartum and postpartum thromboprophylaxis leading to favourable maternal and fetal outcome.
CLINICO-RADIOLOGICAL, ETIOLOGICALAND MICROBIOLOGICAL PROFILE OF EMPYEMA THORACIS: A CROSS-SECTIONAL STUDY.
Authors: Sharma Guneet , Garg Deepak , Garg Vipan
Published: December 2023

Thoracic empyema is an infectious process dened by frank pus in the
pleural space. It is a common chest related condition that carries
1
signicant morbidity and mortality worldwide . The main causes of
thoracic empyema includes pulmonary infections (tuberculosis
accounts for majority) and thoracic trauma. Empyema thoracis
remains a common problem both in the developed as well as
developing countries. Clinical presentation of an empyema depends on
both the nature of infecting organism and the patient's immune
response. It ranges from complete absence of symptoms to severe
illness with systemic toxicity. Clinical presentation of empyema is
highly variable such as respiratory distress, cough, fever, chest pain,
and constitutional symptoms. Pleural empyema results from either
direct contiguous spread of the infection, penetrating chest trauma, or
an iatrogenic condition resulting due to surgical instrumentation of the
2, 3. pleural space Tubercular infection being most common in India
shows low spectrum of bacteriological activity in sputum and pleural
4
uid . The fundamental step in the diagnosis and management of
empyema is chest imaging. Ultrasonography and computed
tomography (CT) scanning have greater sensitivity for uid detection
and provide additional information for determining the extent and
5
nature of the pleural involvement . Empyema thoracis, needs clinical,
microbiological and radiological evaluation for better management
and outcome. Hence this study was conducted in the chest and TB
hospital, Amritsar to study the clinical, radiological and
microbiological prole of empyema.
Unleashing the IoT Revolution in India: Trends, Advantages, Applications, and Strategic Importance
Authors: Sanjay S Tippannavar  , Yashwanth S D
Published: December 2023

The Internet of Things (IoT) represents a revolutionary paradigm where everyday objects are interconnected, enabling them to collect, exchange, and act upon data. This interconnectedness extends beyond traditional computing devices, incorporating a diverse range of physical objects embedded with sensors and actuators. The applications of IoT are vast and impactful, permeating various sectors globally. From smart homes and cities to industrial automation, healthcare, and agriculture, the IoT is driving unprecedented efficiency, convenience, and innovation. Worldwide, the growth of IoT is staggering, with billions of devices already connected and projections indicating exponential expansion. According to recent statistics, the global IoT market reached $201 billion in 2022, showcasing a 21.5% increase, and it is anticipated to surge further, underlining the pervasive integration of IoT into the daily lives of individuals and industrial activities. In the Indian context, the strategic importance of the IoT is paramount. With a rapidly expanding economy and a burgeoning population, India stands to gain significantly from IoT applications. The technology's potential to address challenges in agriculture, healthcare, smart cities, and industrial processes aligns with national development goals. The implementation of IoT in India fosters efficiency, sustainability, and economic growth. As the IoT continues to evolve globally, its transformative impact on India's socio-economic landscape solidifies its role as a catalyst for innovation and progress, promising a future where connectivity and intelligence converge for the betterment of individuals and the nation as a whole. With a focus on trends, contributions, advancements, and applications, this article seeks to broaden the knowledge around IoT in India and functions as a kind of reference for scholars interested in the subject.
Educação em tempo de pandemia: o ensino de língua materna utilizando mídias sociais e aplicativos de comunicação instantânea
Authors: Souza Maria Alice de , Barros Marcelo Diniz Monteiro de
Published: December 2023

A missão da escola é oferecer uma educação que possibilite ao educando extrapolar os saberes formais estabelecidos nos currículos, transformando-se em um cidadão consciente, crítico e criativo pronto para viver em uma sociedade globalizada. Nesse sentido, durante o afastamento social imposto pela pandemia da Covid-19, o grande desafio da escola e dos componentes curriculares têm sido motivar os alunos a continuarem seus estudos a distância. Assim, o presente texto discorre sobre duas propostas pedagógicas, implementadas pelo componente língua portuguesa com os alunos do ensino médio, em 2020, em uma escola da rede pública estadual do município de Belo Horizonte. Essas ações envolveram os/as estudantes em oficinas de produção de texto e fóruns de discussão, contribuindo para que eles/elas compreendessem as dimensões relacionadas às práticas de uso e reflexão da língua.
Desarrollo de una metodología para la gestión de inventarios de flora
Authors: Ochoa-Hernández José Luis , Canizales Dessens Juan Gerardo , Barceló-Valenzuela Mario
Published: December 2023

Dentro de las características de los jardines zoológicos, se detectó que no se cuenta con un inventario de toda la flora, ni mucho menos de la que requiere más cuidados, de igual manera, no se conoce su correcta ubicación y/o distribución, lo que propicia un inadecuado control y mantenimiento de la misma. Para ello, se diseñó e implementó una metodología que guiará mediante un procedimiento adecuado, la definición, creación y uso de los inventarios para el Centro Ecológico de Sonora, el cual permitirá el manejo eficiente de sus recursos. Se analizaron y estudiaron diferentes autores con distintos procedimientos, se generó una propuesta que se pueda implementar en éste y en otros centros. Se debe de considerar que para este tipo de proyectos se requieren equipos de georreferenciación profesionales los cuales eviten el desfase de las coordenadas y una incorrecta ubicación de las especies. Como resultado, se obtuvo...
Complete Whole Genome Sequence of Vibrio parahaemolyticus RP0132 Strain Isolated from Shrimp in Malaysia
Authors: Loo Ke-Yan , Tan Loh Teng-Hern , Law Jodi Woan-Fei , Chua Kah-Ooi , Pusparajah Priyia , Lee Learn-Han , Letchumanan Vengadesh
Published: December 2023

Vibrio parahaemolyticus is a Gram-negative, halophilic bacterium that is ubiquitous in marine environments. Its perilous co-existence with aquatic animals increases the risk of infections and diseases, especially those in aquaculture systems, thus resulting in reduced production and economic losses in the aquaculture industry. Moreover, V. parahaemolyticus can be easily transmitted to humans via consumption of contaminated seafood, resulting in gastroenteritis outbreaks. However, the rise in multidrug resistance within the species has challenged the efficacy of antimicrobial treatments against V. parahaemolyticus infections. Therefore, we report the genome sequence of V. parahaemolyticus RP0132 isolated from shrimp to gain insight into its antimicrobial resistance traits and potential resistance mechanisms. The findings will facilitate the development of effective anti-Vibrio agents to manage V. parahaemolyticus infections.
Impact of Participation in Young Smart Farmer Program on Smallholder Farmers' Income: A Propensity Score Matching Analysis
Authors: Poungchompu Supaporn , Phuttachat Porntip
Published: December 2023

The increase of elderly workers in the agricultural sector will decrease productivity using traditional agriculture production which causes the reduction of income. The Young Smart Farmer program is one of the solutions to solve the problem by developing new generation farmers' agricultural abilities replacing elderly farmers and creating incentives for the new generation to turn to agricultural occupation. Thus, this paper principally assessed the impact of the participation of young farmers in the YSF program on farm income and the determinants of the YSF program factor of young farmer's participation in the YSF program. The total number of samplings is 340 comprising 210 participants and 130 non-participants in the YSF program of the northeast area of Thailand. The data were analyzed using descriptive statistics and the propensity score matching approach to estimate the treatment effect of YSF participation on farm income among smallholder farmers. The results presented that the participants were younger with higher education, more experience and technology support, and had higher farm income compared to non-participants. The propensity scores matching results revealed a significant effect between farmer participation and farm income. The increase in farmers’ income from the participation of young smart farmers was estimated to be approximately 6758.59 $/year compared to non-participants of 3066.63 $/year. To encourage young people to participate more in the YSM program the government should provide more support that can stimulate the young farmers' farming economic activities to improve their quality of living and be fully satisfied with their livelihood. Also, the government should encourage a strong network within the group which consequently increases knowledge sharing, technology, and agricultural activities from the production process to marketing.
Fundamentals of Systematic Management of Business Security
Authors: Ramaz Otinashvili Ramaz Otinashvili , Aleksandre Elisabedashvili Aleksandre Elisabedashvili , Varaz Bedinashvili Varaz Bedinashvili
Published: December 2023

Safety is a complex indicator that includes various areas of the company - management, marketing, personnel management, financial aspects, etc. The more sustainable the business is, the more efficient its business processes are and the less dependent it is on unexpected changes in the market situation. The human factor plays a special role in ensuring business security. As a result, working with staff and preventing malicious attempts on their part is an important part of the company's security system. In the context of a security strategy, depending on the nature of the challenges, an appropriate system of prevention needs to be introduced. It is important to constantly monitor its continuous development. The purpose of the business security system is the correct management of challenges - forecasting, assessment, detection, resolution of crisis situations and planning of preventive measures against possible recurrence. Effective management of the business security system should create conditions for the creation of competitive technologies and goods/services that ensure the successful operation of the facility.
Keywords: business, management, security, system, strategy.
Pengaruh Teknologi Digital, Proses Penganggaran, Dan Sistem Pengendalian Internal Terhadap Performa Koperasi (Studi Kasus Koperasi KSU Parnados Dan CU Hati Nurani Di Kabupaten Rokan Hulu Riau)
Authors: Purba Sahala
Published: December 2023

Riset ini bermaksud untuk mengkaji apakah teknologi digital, proses penganggaran dan Sistem Pengendalian Internal berdampak kepada Performa Koperasi di Koperasi KSU Parnados dan CU Hati Nurani Kabupaten Rokan Hulu Riau. model riset yang dipakai adalah deskriptif kuantitatif. Populasi dalam riset ini seluruh Pengurus dan Karyawan pada Koperasi KSU Parnados dan CU Hati Nurani Kabupaten Rokan Hulu Riau dengan sampel sebanyak 52 orang yang meliputi Pengurus dan Karyawan. Jenis data yang dipakai dalam riset ini adalah data kuantitatif dan sumber datanya data primer, sedangkan teknik dalam pengumpulan data saya memakai kuesioner,  Teknik analisis data yang digunakan dalam riset ini adalah statistik deskriptif serta dalam pengolaan data memakai aplikasi SPSS versi 26. Hasil riset ini memperlihatkan bahwa Teknologi digital, Proses Penganggaran dan Sistem Pengendalian Internal berdampak terhadap Performa Koperasi, begitu juga dalam pengujian secara bersama-sama, bahwa teknologi digital, proses penganggaran dan sistem pengendalian internal berdampak secara bersama-sama terhadap performa koperasi. Sedangkan implikasi dari riset ini adalah dengan adanya penerapan teknologi digital, proses penganggaran dan sistem pengendalian internal akan dapat menaikkan performa koperasi khususnya pada koperasi KSU Parnados dan CU Hati Nurani
Toxicity profile of chemotherapy regimens for multiple myeloma patients using CTCAE Criteria
Authors: V R Antony , Antony Arpith , Kurian Helan , Jiju Jeeva Ann Jiju , Thomas Timy , Sunny Jithin , Abraham Suja
Published: December 2023

Background: Multiple myeloma (MM) is a hematological malignancy of B-cells of plasma cells. The increasing incidence of MM and because of the scarcity of Indian studies on this topic, a detailed study regarding the toxicity profile of chemotherapy regimens for multiple myeloma patients using CTCAE criteria is necessary. Aim: The aim of the study is to investigate the toxicity profile of various chemotherapy regimens in MM patients, specifically using the CTCAE criteria.Methodology: The study is retrospective and clinically based, focusing on MM patients who received different chemotherapy regimens (CyBorD, VD, VRD, TD, and RD) at the Caritas Cancer Institute in Kottayam between 2015 and 2019. Patients meeting specific inclusion and exclusion criteria were selected. Toxicity profiles were analyzed at two-time points: after 4 cycles of treatment (4 months) and at the end of therapy. Results: The study involved 87 patients with a mean age of 64 ± 11.8 years. The majority of patients (83.9%) had MM for less than 2 years. A total of 575 adverse events were reported and categorized based on the CTCAE criteria: 43.5% were Grade 1 (mild), 34.8% were Grade 2 (moderate), 19.1% were Grade 3 (severe), and 2.6% were Grade 4 (life-threatening). The most commonly reported toxicities included anemia, thrombocytopenia, renal failure, and peripheral neuropathy Conclusion: The study's findings suggest that while toxicities were common among MM patients receiving chemotherapy, the majority were of Grade 1 (mild) severity. Very few cases reached Grade 4, which indicates life-threatening consequences. This information can help healthcare professionals and patients make informed decisions regarding the choice of chemotherapy regimens for MM treatment.
Isolation of embelin from embeliaribes berries for the development of topical anti–inflammatory preparation
Authors: R Badmanaban , Padathil Maria S , Parveen Hanna , Joy Dona Merin , Majeed Shahana , S Joycymol , Sen Dhrubo Jyoti
Published: December 2023

Purpose: Embelin is a natural benzoquinone compound, isolated from Embeliaribes berries, known extensively for its anti-inflammatory properties. Due to its hydrophobic nature, it was less explored for topical preparation. Therefore, the purpose of this study was to explore the potential of embelin as an anti-inflammatory agent for topical preparations as well as assess its potential to replace synthetic drugs, which can be resistant to bacterial strains. A topical preparation with embelin would be potentially more effective as well as safer than synthetic drugs.
Method: Embelin has been converted into its potassium salt, and a cream was developed, which was then subjected to physiochemical evaluation. The isolated Embelin and Embelin Potassium salts were characterised by various spectral analysis. The in vitro anti-inflammatory activity was determined by the heat-induced hemolysis and albumin denaturation. Docking scores of embelin and diclofenac were compared and the drug content per gram of cream was estimated.
Result: The UV spectral absorption peak of Embelin  was determined to be at 274 nm, while that of the potassium salt of Embelin was at 515 nm.. The IR  bands were found at 1328.951cm-1,361.74 cm-1, 1616.35 cm -1,1616.35 cm -1 ,1452.4 cm -1, 748.28 cm -1  and 2947.23 cm -1  respectively due to phenolic OH bending, C=O stretching, aromatic ring bending, methylene bending and methyl stretching  . The IR spectra of Embelin potassium salt exhibited similar pattern as that of Embelin but with shifted band due to presence of potassium salt. Heat-induced hemolysis  using diclofenac as standard and embelin potassium salt as test showed  98.01% inhibition and 92% inhibition, respectively, at50µg/ml. The  binding affinity of diclofenac was determined to be -4.9, while the binding affinity of embelin was -5.7, indicating a higher affinity for embelin. Lastly, the drug content per gram of cream was found to be 95%, indicating the amount of active drug (embelin or embelin potassium salt) present in the cream formulation.
Conclusion: Embelin was isolated from Embeliaribes berries and formulated into a herbal cream. The in-vitro studies conducted on the cream showed that it has a significant effect on inflammation . However, in–vivo studies are required for the prepared topical cream to confirm its effectiveness.
Design and characterisation of topical emulgel containing neem oil for its antidandruff properties
Authors: George Eby , Joseph Dhanish , Jabbar Abitha N , M A Khansa Beegam , Joseph Nimisha , Francis Mahima , Boban Anju , Alex Ann Maria
Published: December 2023

Emulgel is a novel drug delivery system for controlled release of drug. It is suitable for the dual release of drugs. This study focuses on the development and characterization of topical emulgel containing neem oil for its anti-dandruff properties. Neem oil is emulsified using suitable surfactant in the ratio 4:2:1 and the prepared emulsion is incorporated with Carbopol gel base in ratio1:1. A total of 5 formulations were prepared using the polymer carbopol-934. Topical emulgel of neem oil was formulated and subjected to evaluation studies such as organoleptic properties, pH, Viscosity, Spreadibility, Invitro diffusion studies, Accelerated stability studies using ultracentrifugation, SEM analysis and Invitro antifungal properties. Formulation F5 subjected to in vitro oil diffusion study had shown a total release of 65.27% after 8 hours. Korsmeyer-Peppa’s plot had shown that the mechanism of diffusion was non-fickian. Emulgel of neem oil shown zone of inhibition on invitro antifungal study using Candida albicans as fungi. Formulation F5 show highest zone of inhibition of 12mm as compared to other formulations. It was concluded that, formulation of neem oil as a semi solid dual release control emulgel formulation with a time dependant oil diffusion, also add up all the advantage of a semisolid dosage compared to liquids with optimum Spreadibility, stability, aesthetic appearance, adherence to the affected scalp area and with pH that is similar scalp.
Development of implantable drug delivery system of embelin for the treatment of breast cancer
Authors: K Rincy. K , Joseph Dhanish , Urumees Binsha , Jose Ann Mariya , Anilan Athira
Published: December 2023

Embelin is a traditional herbal medicine that exhibits anti-cancer effects in human breast cancer cells. However, the therapeutic effect of Embelin as Implantable Drug Delivery System is not yet determined. Embelin is having drawbacks like poor bioavailability and toxicity in systemic circulation, so we opt for Implantable Drug Delivery System. In this study, we optimised, developed and evaluated the Implantable Drug Delivery System of Embelin as pellets. The prime objective of the study is to prolong the drug release as much as possible using a combination of naturally occurring biodegradable polymer such as Guar gum, Chitosan, Xanthan gum, Locust bean gum. In this study, integration of Embelin and Chitosan was achieved via Granulation, with the aid of Guar gum as an excipient, followed by Extrusion /spheronisation. In vitro drug release study revealed the chitosan blended Embelin loaded implant possesses a longer, yet steadier, sustained drug release behaviour than the other three bio polymeric implants. It exhibits prolonged drug release of up to nine days and Korsmeyer’s-peppas plot were exhibited.