bluuebunny/crossref_metadata_2025 huggingface dataset:
Implications of philosophical pragmatism for nursing: Comparison of different pragmatists
Authors: Mayumi Naoya , Ota Katsumasa
Published: October 2022

Pragmatism emphasizes practical consequences and empirical explanations rather than introspective contemplations. However, the arguments of pragmatists are not uniform, as shown by the four prominent pragmatists presented in this article. The major difference between them is that Peirce and Haack acknowledge an objective truth, whereas James and Rorty do not. Thus, for a fuller understanding of the pragmatist view of our knowledge, both camps must be consulted. In the nursing field, pragmatism is occasionally referred to as a guiding philosophy. However, the influence of James and Rorty has been greater than that of Peirce and Haack on pragmatists, which may risk leading to a skewed understanding of pragmatism by nursing scholars. Still, the four pragmatists share naturalism, which rejects a metaphysics that defines the nature of knowledge before our enquiry and emphasizes experience and practice. Pragmatic naturalism can help ensure that nursing theory does not deviate from clinical practice. This article also explores the broad adaptability of the ideas of all four pragmatists to philosophical issues in nursing, such as mixed‐methods research, epistemic relativism and realism. By showing that pragmatism can be relevant and stimulating to each of these topics, the article demonstrates that the different approaches to pragmatism can provide more inspiration for nurses and nursing researchers in the future.
Pathophysiology and management of hypoglycemia in diabetes
Authors: Sanchez‐Rangel Elizabeth , Deajon‐Jackson Jelani , Hwang Janice Jin
Published: October 2022

In the century since the discovery of insulin, diabetes has changed from an early death sentence to a manageable chronic disease. This change in longevity and duration of diabetes coupled with significant advances in therapeutic options for patients has fundamentally changed the landscape of diabetes management, particularly in patients with type 1 diabetes mellitus. However, hypoglycemia remains a major barrier to achieving optimal glycemic control. Current understanding of the mechanisms of hypoglycemia has expanded to include not only counter‐regulatory hormonal responses but also direct changes in brain glucose, fuel sensing, and utilization, as well as changes in neural networks that modulate behavior, mood, and cognition. Different strategies to prevent and treat hypoglycemia have been developed, including educational strategies, new insulin formulations, delivery devices, novel technologies, and pharmacologic targets. This review article will discuss current literature contributing to our understanding of the myriad of factors that lead to the development of clinically meaningful hypoglycemia and review established and novel therapies for the prevention and treatment of hypoglycemia.
An autopsy case of hyperimmunoglobulin E syndrome with coronary fibrinoid necrotizing arteritis and an aneurysm
Authors: Sugimoto Ryo , Yanagawa Naoki , Osakabe Mitsumasa , Uesugi Noriyuki , Yamada Noriyuki , Kitada Yuriko , Yamashita Rina , Saito Hidenori , Sugai Tamotsu
Published: October 2022

We report a case of hyperimmunoglobulin (Ig) E syndrome (HIES) with a coronary artery aneurysm (CAA) in a 25‐year‐old Japanese man. He died suddenly due to chronic heart failure associated with HIES. We noted a CAA at the trunk of the left coronary artery and granulomatous and fibrinoid necrotizing arteritis of the middle portion of the left anterior descending during the autopsy. We speculate herein on the relationship between the aneurysm and arteritis. These findings facilitate a better understanding of the pathogenesis underlying HIES.
The influence of creeping slope failure on turbidity current behaviour
Authors: Ayckbourne Ashley J. M. , Jerrett Rhodri M. , Poyatos‐Moré Miquel , Watkinson Matthew P. , Kane Ian A. , Taylor Kevin G.
Published: October 2022

Erosional scars, slumps, slides and debrites (mass‐transport deposits) on submarine slopes form relief that influences turbidity current behaviour. However, the interaction of mass‐transport deposit emplacement kinematics (i.e. rapid emplacement versus creep), the morphology of the evolving seafloor topography and subsequent flow types is complicated. This study describes two outcrop examples of deep‐water, predominantly turbiditic, deposits overlying mass‐transport deposits, from the Eocene slope succession of the Aínsa Basin (Spanish Pyrenees). In both examples, the mass‐transport deposit substrate continued to creep contemporaneously with turbidity current deposition and bypass. In the first case study, structures in the mass‐transport deposits are extensional and oriented parallel to flow. In the second, structures are compressional and oriented perpendicular to flow. Mudstones dominate the slope succession, but deposits overlying mass‐transport deposits form sandstone‐prone accumulations. Lateral confinement by flow‐parallel extensional faults enhanced channel‐formation. Channel incision occurred close to the exhumed fault plane on the hangingwall. Incision ceased as the fault gradually locked‐up, and channels avulsed to the hangingwall of a newly active normal fault, while the abandoned channel was filled by a thinning and fining‐upward succession. Barriers formed where the long axes of compressional anticlines developed in mass‐transport deposits formed perpendicular to flow. Here, turbidites filled the bathymetric lows in the axes of synclines. Continued tightening of synclinal depocentres led to repeated stoss side trapping and upslope accretion of coarse‐grained sediment accumulation. This generated thickening and coarsening‐up, followed by thinning and fining‐upward successions, tracking the decreasing, then increasing flow bypass associated with topographic expression on the mass‐transport deposit. This study shows how post‐emplacement creep, and orientation of topographic features on mass‐transport deposits, influence the routing and deposition of contemporaneous turbidity currents, and illustrates examples of facies successions that could be misinterpreted as the product of other autogenic submarine slope processes, such as lateral migration of sinuous channels, or compensational lobe stacking.
Ocean expansion: The role of detachment faults
Authors: Chalot‐Prat Françoise , Magott Rémi , Berthod Carole
Published: October 2022

Detachment faulting at slow spreading ocean ridge axes is recognized as a major surface creation mechanism, yet the structural relationships of these faults with feeder‐dykes of on‐axis volcanoes remained unresolved. This summary study shows that surface creation leading to ocean widening is exclusively controlled by detachment faults, shallow tracers of tectonic stresses induced by the westward drift of plates. Volcanoes are fed by feeder‐dykes following on‐axis rotational detachment faults. Once formed volcanoes are dragged along the detachment whose footwall is made of mantle material sometimes hosting gabbro sills. Due to the faster drift of the uppermost lithospheric layer, the feeder‐dykes are then intersected by active deeper low‐angle detachments, become inactive and are replaced by new ones on‐axis. Rooted vertically on either side of the plate boundary, the detachment flexing is all the earlier and more progressive as the faults are far from the axis, positioning gabbro as sills at shallow level within a deformed mantle interspersed with cataclasite horizons. Correlations between shallow and deep lithospheric processes are then clarified.
Vertical deformation partitioning across a collapsing large and hot orogen
Authors: Temporim F. A. , da Trindade Ricardo Ivan Ferreirae , Egydio‐Silva Marcos , Angelo Tiago Valim , Tohver Eric , Soares Caroline Cibele , Gouvêa Lucas Pequeno , Mendes Julio Cesar , Medeiros Silvia Regina , Pedrosa‐Soares Antônio Carlos , Silva Gabriel Gomes
Published: October 2022

Featuring 3 000‐km‐long large and hot orogen, the Mantiqueira Province provides a rare opportunity to study the process of gravitational collapse at mid to deep crustal levels. Distinct but contemporary (~500 Ma) post‐collisional intrusions show structures and anisotropy of magnetic susceptibility (AMS) fabrics related to their emplacements, recording different flow patterns. In southern deep‐seated intrusions, ellipsoidal‐shaped roots with gabbroic‐to‐hybrid cores surrounded by granitic rocks show concentric patterns of AMS fabrics that cut across the NE‐trending regional foliation. In contrast, northern intrusions, exposed as the upper sections of batholith‐size bodies of coarse‐grained granite emplaced at the shallow to mid‐crust, show general NS‐trending magnetic fabrics roughly parallel to strike of the orogen and the regional foliation of host rocks. These contrasting magnetic patterns from shallow to deeper crust suggest vertical magma migration from the overthickened orogenic core to be emplaced across its thinner stretched flanks during the gravitational collapse of the orogenic edifice.
Mathematical Models of the Generation of Radiation-induced DNA Double-strand Breaks and Misrepair Cells by Direct and Indirect Action
Authors: Rashid Hamizah , Mohd Siam Fuaada , Maan Normah , W. Abd Rahman Wan Nordiana , Nasir Mohamad Hanis
Published: October 2022

Free radical carries an unpaired electron in the outer shell which is very reactive and becomes toxic to DNA. The direct action hits cell directly, while indirect action is the interaction between ionizing radiation and water molecule which later produces free radical. Hydrated electron (e), hydroxyl radical (OH), hydrogen radical (OH), ionized water, hydroperoxyl radical and hydrogen peroxide are examples of free radical products. Among of these three free radicals, DNA damage dominantly caused by hydroxyl radical (OH) because it is found to be highly reactive compared to others. This paper aimed to develop a model by using structured population dynamics approach to study the effects of ionizing radiation by direct and indirect actions. The effects of ionizing radiation are mathematically described in a model using Ordinary Differential Equations (ODEs). The simulation results are fitted to the Linear Quadratic (LQ) formulation to give the ratio for alpha/beta . Next, the parameter estimation of the model is carried out using experimental data of human colon carcinoma cell by the aid of the MATLAB programming. The estimated parameter values can explain the biological meaning, which can support the result of the experimental design. The result showed that the sum-squared error (SSE) between simulation data and experimental data obtained is 0.0019 which indicates an excellent t to the experimental data. Thus, the model developed is in line with the experimental result. The model is able to explain the dynamics process of the direct and indirect effect of ionizing radiation on the cell population.
Analysis of Unsteady Solute Dispersion in a Blood Flow of Herschel-Bulkley through a Catheterized Stenosed Artery
Authors: Munir Intan Diyana , Jaafar Nurul Aini , Shafie Sharidan
Published: October 2022

Blockage of blood flow due to cholesterol deposits at the arterial wall, known as stenosis, can lead to conditions such as heart attack and stroke. Treatment such as balloon angioplasty involves the catheterization of an artery where a stented catheter is inflated at the stenosis site to open the narrowed artery. The catheterization of the stenosed artery affects the surrounding blood flow and dispersion process. The present study analyses the effect of catheter radius and stenosis height on the blood velocity and solute dispersion behavior. Herschel-Bulkley fluid is used to model the problem with stenosis as the boundary condition. The momentum equation and Herschel-Bulkley constitutive equation are solved analytically into integral forms. Simpson’s 3/8 rule and Regula-Falsi method were used to evaluate the integral numerically to obtain the velocity. The velocity was utilized to solve the unsteady convective-diffusion equation using the generalized dispersion model (GDM) to obtain the dispersion function. This present research can potentially help the medical field and industry in determining the suitable catheter radius for patients, calculating drug dosage and improving stent catheter design. Results show that the velocity decreases as the catheter radius and stenosis height increase. A decrease in velocity simultaneously increases the solute dispersion function.
Genetic Algorithm for Optimal Vendor Payment Schedule of Transportation Company
Authors: Johar Farhana , Houy Fen Ng , Nordin Syarifah Zyurina
Published: October 2022

Nowadays, businesses in any sector are under pressure to do more with less. Company cannot afford to pay more and squander opportunities to free up their company’s cash, i.e. working capital. Good working capital gives greater availability to the cash trapped on your balance sheet which is beneficial to fund growth, reduce costs, enhance service levels and seize new investment opportunities. There are numerous ways to free up working capital, and one of the strategies is through account payable. Account payable are amounts due to vendor or supplier for goods or services received that have not yet been paid for. Thus, this paper focuses on the proper vendor payment schedule as one of the approaches to sustain the liquidity of business. Optimizing the vendor payment schedule could be observed through their Net Present Value (NPV). NPV is the difference between the present value of cash inflows and outflows. Therefore, our aim is to optimize the vendor payment schedule by maximizing their NPV. Genetic Algorithm (GA) is implemented in determining the optimal vendor payment schedule. Two GA parameters, which are generation number and population size, have been analyzed and optimized in order to meet the maximum NPV. The results show that the GA is efficient in maximizing the NPV of vendor payment schedule.
Control of blood pressure in the cold: differentiation of skin and skeletal muscle vascular resistance
Authors: Mugele Hendrik , Marume Kyohei , Amin Sachin B. , Possnig Carmen , Kühn Lucie C. , Riehl Lydia , Pieper Robin , Schabbehard Eva‐Lotte , Oliver Samuel J. , Gagnon Daniel , Lawley Justin S.
Published: October 2022

The primary aim of this investigation was to determine the individual contribution of the cutaneous and skeletal muscle circulations to the cold‐induced pressor response. To address this, we examined local vascular resistances in the cutaneous and skeletal muscle of the arm and leg. Thirty‐four healthy individuals underwent three different protocols, whereby cold air to clamp skin temperature (27°C) was passed over (1) the whole‐body, (2) the whole‐body, but with the forearm pre‐cooled to clamp cutaneous vascular resistance, and (3) the face. Cold exposure applied to the whole body or isolated to the face increased mean arterial pressure (all, P < 0.001) and total peripheral resistance (all, P < 0.047) compared to thermal neutral baseline. Whole‐body cooling increased femoral (P < 0.005) and brachial artery resistance (P < 0.003) compared to thermoneutral baseline. Moreover, when the forearm was pre‐cooled to remove the contribution of cutaneous resistance (P = 0.991), there was a further increase in lower arm vasoconstriction (P = 0.036) when whole‐body cooling was superimposed. Face cooling also caused a reflex increase in lower arm cutaneous (P = 0.009) and brachial resistance (P = 0.050), yet there was no change in femoral resistance (P = 0.815) despite a reflex increase in leg cutaneous resistance (P = 0.010). Cold stress causes an increase in blood pressure through a change in total peripheral resistance that is largely due to cutaneous vasoconstriction with face cooling, but there is additional vasoconstriction in the skeletal muscle vasculature with whole‐body cooling.
Ensemble Learning Approach to the Prediction of Gas Turbine Trip
Authors: Losi Enzo , Venturini Mauro , Manservigi Lucrezia , Bechini Giovanni
Published: October 2022

In the field of gas turbine (GT) monitoring and diagnostics, GT trip is of great concern for manufactures and users. In fact, due to the number of issues that may cause a trip, its occurrence is not infrequent, and its prediction is a quite unexplored field of research. This is demonstrated by the fact that, despite its relevance, a comprehensive study on the reliability of predicting GT trip has not been proposed yet. To fill this gap, this paper investigates the fusion of five data-driven base models by means of voting and stacking, in order to improve prediction accuracy and robustness. The five benchmark supervised machine learning and deep learning classifiers are k-nearest neighbors, support vector machine (SVM), Naïve Bayes (NB), decision trees (DTs), and long short-term memory (LSTM) neural networks. While voting just averages the predictions of base models, without providing additional pieces of information, stacking is a technique used to aggregate heterogeneous models by training an additional machine learning model (namely, stacked ensemble model) on the predictions of the base models. The analyses carried out in this paper employ filed observations of both safe operation and trip events, derived from a large fleet of industrial Siemens GTs in operation. The results demonstrate that the stacked model provides higher accuracy than base models and also outperforms voting by proving more effective, especially when the reliability of the prediction of base models is poor.
Mentored student research: A case study evaluation of benefits and best practices
Authors: Vongsawad Cameron T. , Bennion Adam H. , Hollingsworth Scott P. , Terry Kaylyn N. , Dobbs Corey E. , Fronk Gabriel H. , Neilsen Tracianne B.
Published: October 2022

Efforts to mentor undergraduates in research require time, energy, and resources but can yield significant benefits. A review of education research on undergraduate research is presented followed by a case study of how technical and educational principles from the literature have been implemented and practiced in a new underwater acoustics lab. This case study involves the students who have joined this lab over its first three years. The results highlight the importance of several key factors that mentors can implement to improve their students' research experience. In order to meet the steep learning curve that new students face, faculty mentors should establish a culture of research (i.e., well established norms, expectations, and practices associated with being a part of a research group) through clear expectations, open communication, and student-led peer mentorship supported by carefully selected or designed resources (i.e., scaffolding). This paper seeks to share these education research resources with the acoustics community while providing a case study for review as a specific application of these key principles into an acoustics laboratory setting.
Loss-of-function mutations inCEP78cause male infertility in humans and mice
Authors: Zhang Xueguang , Zheng Rui , Liang Chen , Liu Haotian , Zhang Xiaozhen , Ma Yongyi , Liu Mohan , Zhang Wei , Yang Yang , Liu Man , Jiang Chuan , Ren Qingjia , Wang Yan , Chen Suren , Yang Yihong , Shen Ying
Published: October 2022

Centrosomal protein dysfunction might cause ciliopathies. However, the role of centrosomal proteins in male infertility remains poorly defined. Here, we identified a pathogenic splicing mutation inCEP78in male infertile patients with severely reduced sperm number and motility, and the typical multiple morphological abnormalities of the sperm flagella phenotype. We further createdCep78knockout mice, which showed an extremely low sperm count, completely aberrant sperm morphology, and approximately null sperm motility. The infertility of the patients and knockout mice could not be rescued by an intracytoplasmic sperm injection treatment. Mechanistically, CEP78 might regulate USP16 expression, which further stabilizes Tektin levels via the ubiquitination pathway.Cep78knockout mice also exhibited impairments in retina and outer hair cells of the cochlea. Collectively, our findings identified nonfunctional CEP78 as an indispensable factor contributing to male infertility and revealed a role for this gene in regulating retinal and outer hair cell function in mice.
Stop passing the buck on intro science
Authors: Thorp H. Holden
Published: October 2022

The recent firing of Maitland Jones Jr. by New York University (NYU) has captured the attention of many quarters in higher education and science in the United States. Jones, a celebrated organic chemistry professor at Princeton University, who retired and became a contract professor at NYU, was dismissed after some of his students complained about their grades and the challenging level of the material in a large introductory class on organic chemistry. Even though the students never asked for Jones to be fired, NYU didn’t renew his 1-year contract and sent him on his way. This reaction is illustrative of the problem of intro science, particularly at highly selective colleges: Universities would rather wash their hands of such matters than deal with all of the thorny issues revealed by stories like this. Until they do, many students will leave the courses disappointed and mistrustful of science, just at the time that science needs their support.
Emergence of a Fatal ST11-KL64 Tigecycline-Resistant Hypervirulent Klebsiella pneumoniae Clone Cocarrying
bla
NDM
and
bla
KPC
in Plasmids
Authors: Huang Jinzhu , Yi Miao , Yuan Yaling , Xia Peiwen , Yang Bingxue , Liao Jiajia , Dang Zijun , Luo Shengli , Xia Yun
Published: October 2022

Infections with CRKP coproducing KPC and NDM currently have limited clinical antibacterial options, and tigecycline is used as the last line of defense for therapy. However, this study found that CR-hvKP infection with tigecycline resistance, which may lead to many bacteria being resistant to most commonly used antibiotics, brought significant challenges to clinical treatment. The clonal propagation of ST11-KL64 CRKP should receive sufficient attention.
Supplemental Material: Heavy Mo isotope composition of northern Bataan adakites, Philippines: Evidence for fore-arc subduction erosion?
Authors: Liu Hai-Quan , al. et
Published: October 2022

Geological background, sample information, methods, and supplemental discussion and tables. 
Extraction and Determination of Synthetic Food Dyes in an Aqueous Biphasic System Based on Tetrabutylammonium Bromide
Authors: Lyskovtseva K. A. , Eldyaeva G. B. , Smirnova S. V. , Pletnev I. V.
Published: October 2022

An aqueous biphasic system (ABS) based on tetrabutylammonium bromide (TBABr) with ammonium sulfate as a salting-out agent was used to extract synthetic food dyes from aqueous solutions. Conditions for the preparation of the TBABr–H2O–(NH4)2SO4 ABS for microextraction preconcentration of Allura Red, Tartrazine, Azorubine, Sunset Yellow, and Fast Green were optimized: tetrabutylammonium bromide, 0.075 M and ammonium sulfate, 33 wt %. The recovery of all of the dyes was no lower than 97% at pH 2.3–9.5 for 1 min. Filtration through nonwoven polypropylene was used to facilitate phase separation and extract isolation. The concentrate was eluted with distilled water, and the dyes in the eluate were determined by spectrophotometry. The limits of detection were 0.02, 0.03, 0.03, 0.04, and 0.02 mg/L for Allura Red, Azorubine, Tartrazine, Sunset Yellow, and Fast Green, respectively. The procedure was applied to determine dyes in drinks, a mouthwash, an Easter kit for dyeing eggs, and the drug Ibuprofen.
Delayed and prolonged umbilical stump bleeding in a Caucasian newborn as a presenting feature of factor XIII deficiency
Authors: Lim David Boon Ngan , Mangles Sarah , Goturu Aruna
Published: October 2022

A term Caucasian neonate with an uncomplicated birth history presented with persistent umbilical stump bleeding unresponsive to extensive topical haemostatic measures initially. He subsequently developed hypovolaemic shock. Routine full blood count and basic coagulation screen were unremarkable. He received packed red cell and cryoprecipitate transfusions. Further specialist coagulation studies performed revealed factor XIII deficiency. Genetic investigations demonstrated a compound heterozygosity for the disorder. He was later started on monthly prophylactic treatment of plasma-derived factor XIII. Clinicians should have a high index of suspicion for factor XIII deficiency for newborns with abnormal umbilical stump bleeding in the presence of no bleeding risk factors and normal routine blood investigations.
Impact of the COVID-19 pandemic on opioid overdose and other adverse events in the USA and Canada: a systematic review
Authors: Simha Siddartha , Ahmed Yusuf , Brummett Chad M , Waljee Jennifer F , Englesbe Michael J , Bicket Mark C
Published: October 2022

Importance

The COVID-19 pandemic impacted healthcare beyond COVID-19 infections. A better understanding of how COVID-19 worsened the opioid crisis has potential to inform future response efforts.

Objective

To summarize changes from the COVID-19 pandemic on outcomes regarding opioid use and misuse in the USA and Canada.

Evidence review

We searched MEDLINE via PubMed, EMBASE, and CENTRAL for peer-reviewed articles published between March 2020 and December 2021 that examined outcomes relevant to patients with opioid use, misuse, and opioid use disorder by comparing the period before vs after COVID-19 onset in the USA and Canada. Two reviewers independently screened studies, extracted data, assessed methodological quality and bias via Newcastle-Ottawa Scale, and synthesized results.

Findings

Among 20 included studies, 13 (65%) analyzed service utilization, 6 (30%) analyzed urine drug testing results, and 2 (10%) analyzed naloxone dispensation. Opioid-related emergency medicine utilization increased in most studies (85%, 11/13) for both service calls (17% to 61%) and emergency department visits (42% to 122%). Urine drug testing positivity results increased in all studies (100%, 6/6) for fentanyl (34% to 138%), most (80%, 4/5) studies for heroin (-12% to 62%), and most (75%, 3/4) studies for oxycodone (0% to 44%). Naloxone dispensation was unchanged and decreased in one study each.

Interpretation

Significant increases in surrogate measures of the opioid crisis coincided with the onset of COVID-19. These findings serve as a call to action to redouble prevention, treatment, and harm reduction efforts for the opioid crisis as the pandemic evolves.

PROSPERO registration number

CRD42021236464.
Soil fumigation with Vapam (metam sodium) to control clubroot (Plasmodiophora brassicae) of canola (Brassica napus)
Authors: Zuzak Krista A. , Strelkov Stephen E. , Turnbull George D. , Manolii Victor P. , Hwang Sheau-Fang
Published: October 2022

Clubroot, a damaging disease of canola ( Brassica napus L.) caused by the soilborne parasite Plasmodiophora brassicae Woronin, is spreading across Alberta and other provinces of western Canada. The movement of infested soil on field machinery is the main mechanism of dispersal, with clubroot generally occurring first as localized patches near field entrances. In this study, the soil fumigant Vapam (metam sodium) was evaluated as a management option for foci of P. brassicae infestation. Replicated experiments at two field sites in central Alberta showed reductions in clubroot severity ranging from 9% to 51% following treatment with varying rates of Vapam. Decreases in clubroot severity of up to 28% were observed in the year following Vapam treatment, indicating some potential residual effects and (or) a reduction in the amount of inoculum returned to the soil in the previous year. While Vapam shows some promise as a clubroot management tool, an integrated approach will be required for the sustainable management of this disease on canola.
A Sentiment Analysis Anomaly Detection System for Cyber Intelligence
Authors: Maisano Roberta , Foresti Gian Luca
Published: October 2022

Considering the 2030 United Nations intent of world connection, Cyber Intelligence becomes the main area of the human dimension able of inflicting changes in geopolitical dynamics. In cyberspace, the new battlefield is the mind of people including new weapons like abuse of social media with information manipulation, deception by activists and misinformation. In this paper, a Sentiment Analysis system with Anomaly Detection (SAAD) capability is proposed. The system, scalable and modular, uses an OSINT-Deep Learning approach to investigate on social media sentiment in order to predict suspicious anomaly trend in Twitter posts. Anomaly detection is investigated with a new semi-supervised process that is able to detect potentially dangerous situations in critical areas. The main contributions of the paper are the system suitability for working in different areas and domains, the anomaly detection procedure in sentiment context and a time-dependent confusion matrix to address model evaluation with unbalanced dataset. Real experiments and tests were performed on Sahel Region. The detected anomalies in negative sentiment have been checked by experts of Sahel area, proving true links between the models results and real situations observable from the tweets.
INVITED PAPER — A CONJECTURE ON THE ORIGINS AND EVOLUTION OF MARKETS
Authors: SANDOR RICHARD L.
Published: October 2022

The author shares his theory on market creation and evolution from his perspective as an academic and a practitioner who has been involved in financial innovation for five decades. Rather than being spontaneously created, markets appear to follow a clear set of steps (the “seven-stage” process) from inception to maturity. It is critical that the benefits from transacting are greater than the costs of establishing the market — otherwise the evolution does not occur. Historical examples of the process outlined by the author can be found in commodity, equity, fixed income and environmental markets. The author provides observations and lessons that his evolutionary framework shares with financial inventive activity in new and existing products in our rapidly evolving digital world. Recent digital innovations such as the blockchain have evolved in a framework that did not require a legislative or regulatory framework (or what the author calls a “permissionless” environment). A properly designed regulatory environment can be permissionless regarding inventive activity (withness the Commodity Futures Trading Commission in the United States). A permissionless environment has historical precedent in other “analog” innovations such as wheat trading in the 19th century or financial futures in the mid-1970s. Following the seven-stage process, those innovations arose from structural changes or latent economic demands. Their standards and infrastructure were only much later understood and adopted by the regulators. Given that, the author suggests that since changes now occur at hyper speed, the implications for the future shape of derivatives markets are likely to be profound.
Constraints from new CDF II W-boson mass on top–bottom seesaw and the topflavor models
Authors: Liu Guo-Li
Published: October 2022

In top–bottom seesaw and topflavor model, there may exist extra Higgs bosons and vector-like fermions, and we have examined the W-mass anomaly reported by CDF II in these frames. We found that the CDF II W-boson mass data constrains the parameter [Formula: see text] and [Formula: see text] strictly in the two models, respectively, while the constraints on other parameters such as [Formula: see text], [Formula: see text] are quite weak. Therefore, we conclude that in the two models, the W-mass increment is sensitive to the extra fermions, but not the extra scalars. In topFlavor model, we also consider the W-mass increment induced by the mass mixing of the light and the heavy gauge bosons and the contribution is not too large and the constraints on the parameters [Formula: see text] and [Formula: see text] are weak.
Multiplexing new physics search at high-energy lepton colliders
Authors: Franceschini Roberto
Published: October 2022

In this talk I give a snapshot of the ongoing discussion on new physics searches at future colliders. I discuss the unique opportunities of a high energy lepton collider operating at multi-TeV center-of-mass energy and in particular its peculiar capability to carry out at the same time "intensity'' searches with the copious production of Standard Model states as well as directly producing heavy new physics states or probing still heavier new physics via indirect effects.
Dual QCD thermodynamics at finite temperature and chemical potential
Authors: Punetha Garima , Bandyopadhyay Aritra , Bisht Shuchi
Published: October 2022

A Dual QCD formulation for [Formula: see text] color gauge has been developed in terms of dual gauge potentials, building on our previously published study for the [Formula: see text] case with zero bario-chemical potential [H. C. Chandola, G. Punetha and H. Dehnen, Nucl. Phys. A 945, 226 (2016).] and taking into account the local as well as topological structure of the color gauge group into its dynamics. For the purpose of examining the nonperturbative characteristics of QCD, the dynamical configuration of the resulting dual QCD vacuum and its flux tube configuration have been examined. The thermal behavior of the nonperturbative QCD vacuum has been investigated for exploring the dynamics of quark-hadron phase transition at finite chemical potential. Related thermodynamic quantities and equation of state (EoS) to characterize quark matter have also been discussed within the framework of dual QCD-based hadronic bag which guarantees the critical parameters and the associated critical points for quark-hadron phase transition. These thermodynamic quantities are expected to play important roles in understanding the order of quark-hadron phase transition and are likely to predict the features of a first-order quark-hadron phase transition for finite chemical potential. Moreover, we have investigated the bulk properties of quark matter by constructing the free energy change and the associated surface tension for quark-hadron phase transition. For consistency and compatibility check, we have also compared our results with state-of-the-art three-loop Hard Thermal Loop perturbative results and available lattice QCD results and in the process found reasonable agreements.
Alternative for black hole paradoxes
Authors: Slagter Reinoud Jan
Published: October 2022

In this paper, we investigate the exact time-dependent black hole solution on a warped five-dimensional Randall–Sundrum space–time in conformal dilaton gravity. The zeroes of the model are described by a meromorphic quintic polynomial, which has no essential singularities. The quintic equation can be reduced to the Brioschi form by means of the Weierstrass elliptic curve over [Formula: see text]. The model fits the antipodal boundary condition, i.e. antipodal points in the projected space are identified using the embedding of a Klein surface in [Formula: see text], using the [Formula: see text] symmetry on the two sides of the brane. If one writes [Formula: see text], [Formula: see text], with [Formula: see text] the normal to the brane and [Formula: see text] the dilaton field, then [Formula: see text] is conformally flat. It is the contribution from the bulk which determines the real pole on the effective four-dimensional space–time. There is no objection applying ’t Hooft’s back reaction method in constructing the unitary S-matrix for the Hawking radiation. Again, there is no “inside” of the black hole. The zeroes can also be analyzed by the icosahedron equation and by the Hopf-fibration of the Klein surface.
A Pattern Mining Approach for Improving Speech Emotion Recognition
Authors: Avci Umut
Published: October 2022

Speech-driven user interfaces are becoming more common in our lives. To interact with such systems naturally and effectively, machines need to recognize the emotional states of users and respond to them accordingly. At the heart of the emotion recognition research done to this end lies the emotion representation that enables machines to learn and predict emotions. Speech emotion recognition studies use a wide range of low-to-high-level acoustic features for representation purposes such as LLDs, their functionals, and BoAW. In this paper, we present a new method for extracting a novel set of high-level features for classifying emotions. For this purpose, we (1) reduce the dimension of discrete-time speech signals, (2) perform a quantization operation on the new signals and assign a distinct symbol to each quantization level, (3) use the symbol sequences representing the signals to extract discriminative patterns that are capable of distinguishing different emotions from each other, and (4) generate a separate set of features for each emotion from the extracted patterns. Experimental results show that pattern features outperform Energy, Voicing, MFCC, Spectral, and RASTA feature sets. We also demonstrate that combining the pattern-based features and the acoustic features further improves the classification performance.
Making Technical Debt Visible Using Hybrid Sankey Diagrams: An Industrial Case Study
Authors: Pacheco Alexia , Marín-Raventós Gabriela , Spínola Rodrigo , López Gustavo , Seaman Carolyn
Published: October 2022

Context: Technical debt (TD) is a challenge for companies who develop software on which their critical operations depend. To properly manage TD, it is necessary to make it visible to the different stakeholders involved to support informed decisions. Objective: To validate a TD visualization approach based on hybrid Sankey diagrams that makes the TD visible by showing (a) technical and business aspects, and (b) the flow of value and TD impacts. This approach regards visualizations as boundary objects. Method: We performed a multi-case study in a large multi-industry state-owned company. The objective was to validate the effectiveness of such visualizations and to explore their possible uses in TD management. We first used a retrospective case study on a TD decision-making scenario and, later, visualization usage scenarios using focus groups to evaluate its usefulness. Results: The results suggest that the proposed approach: (a) provides a structured process for systematic TD visualization to help the decision-making process; (b) enables the communication at knowledge boundaries between stakeholders to make informed decisions; (c) uses flow representations that are important for assessing the impact in multiple functional areas; and (d) enables documentation and reuse. Conclusion: The study results suggest that TD decision-making events can benefit from using our TD visualizations based on hybrid Sankey diagrams as boundary objects to portray the impact of TD in business, services, and technical aspects.
On irreducibility of Gaussian quantum Markov semigroups
Authors: Fagnola Franco , Poletti Damiano
Published: October 2022

The generator of a Gaussian quantum Markov semigroup on the algebra of bounded operator on a [Formula: see text]-mode Fock space is represented in a generalized GKLS form with an operator [Formula: see text] quadratic in creation and annihilation operators and Kraus operators [Formula: see text] linear in creation and annihilation operators. Kraus operators, commutators [Formula: see text] and iterated commutators [Formula: see text] up to the order [Formula: see text], as linear combinations of creation and annihilation operators determine a vector in [Formula: see text]. We show that a Gaussian quantum Markov semigroup is irreducible if such vectors generate [Formula: see text], under the technical condition that the domains of [Formula: see text] and the number operator coincide. Conversely, we show that this condition is also necessary if the linear space generated by Kraus operators and their iterated commutator with [Formula: see text] is fully non-commutative.
Multivariate generalized splines and syzygies on graphs
Authors: Sarioglan Samet , Altinok Selma
Published: October 2022

Given a graph [Formula: see text] whose edges are labeled by ideals of a commutative ring [Formula: see text] with identity, a generalized spline is a vertex labeling of [Formula: see text] by the elements of [Formula: see text] so that the difference of labels on adjacent vertices is an element of the corresponding edge ideal. The set of all generalized splines on a graph [Formula: see text] with base ring [Formula: see text] has a ring and an [Formula: see text]-module structure. In this paper, we focus on the freeness of generalized spline modules over certain graphs with the base ring [Formula: see text] where [Formula: see text] is a field. We first show the freeness of generalized spline modules on graphs with no interior edges over [Formula: see text] such as cycles or a disjoint union of cycles with free edges. Later, we consider graphs that can be decomposed into disjoint cycles without changing the isomorphism class of the syzygy modules. Then we use this decomposition to show that generalized spline modules are free over [Formula: see text] and later we extend this result to the base ring [Formula: see text] under some restrictions.
On commutator-inversion invariant groups and gyrogroup construction
Authors: Suksumran Teerapong
Published: October 2022

This paper introduces the notion of commutator-inversion invariance and studies several algebraic properties of commutator-inversion invariant groups. Then, a characterization of 2-Engel groups is given, and it is shown that any group whose central quotient is commutator-inversion invariant gives rise to a non-associative structure called a gyrogroup. This method yields three non-degenerate gyrogroups of order 16 as concrete examples.
Fruit Quality Grading Using Texture Feature-Based PLS-DA Technique
Authors: Bhanuse Manisha Vikas , Patil S. B.
Published: October 2022

During the postharvesting of horticulture, the grading of the fruit is significant because it determines the satisfaction and preference of the consumers while reaching the market. The fruit grading using the physical classification is an expensive task and inaccurate classification may occur due to human errors. Thus, there is a need for automatic fruit grading using the non-destructive process. This research proposes an efficient fruit grading technique using the partial least squares-discriminant analysis (PLS-DA technique) based on the texture features. Here, the features such as local binary pattern (LBP), local directional pattern (LDP), local optimal oriented pattern (LOOP), local gradient pattern (LGP), and Local Ternary Pattern (LTP) are extracted for the classification of the fruit. The feature extraction based on these texture features is employed after pre-processing the multi-spectral input image. From, the extracted features, the classification of fruit such as apple, banana, pomegranate, and mango are employed. Then, the parameters such as firmness, soluble solids concentration (SSC), and titratable acidity (TAC) are evaluated for the fruit quality grading using the PLS-DA technique. The proposed method is evaluated in terms of accuracy, error, [Formula: see text], residual predictive deviation (RPD), sensitivity, and specificity and obtained the values of 95.67%, 4.33, 92.97%, 0.05, 95.66%, and 95.17% respectively.
Regulation of actin cytoskeleton via photolithographic micropatterning
Authors: Xing Fulin , Zhang Haimei , Li Mengyu , Dong Hao , Ma Xuehe , Deng Shiyu , Hu Fen , Lee Imshik , Pan Leiting , Xu Jingjun
Published: October 2022

Actin cytoskeleton plays crucial roles in various cellular functions. Extracellular matrix (ECM) can modulate cell morphology by remodeling the internal cytoskeleton. To define how geometry of ECM regulates the organization of actin cytoskeleton, we plated individual NIH 3T3 cells on micropatterned substrates with distinct shapes and sizes. It was found that the stress fibers could form along the nonadhesive edges of T-shaped pattern, but were absent from the opening edge of V-shaped pattern, indicating that the organization of actin cytoskeleton was dependent on the mechanical environment. Furthermore, a secondary actin ring was observed on 50[Formula: see text][Formula: see text]m circular pattern while did not appear on 30[Formula: see text][Formula: see text]m and 40[Formula: see text][Formula: see text]m pattern, showing a size-dependent organization of actin cytoskeleton. Finally, osteoblasts, MDCK and A549 cells exhibited distinct organization of actin cytoskeleton on T-shaped pattern, suggesting a cell-type specificity in arrangement of actin cytoskeleton. Together, our findings brought novel insight into the organization of actin cytoskeleton on micropatterned environments.
Constructing nanosheets-self-supported structure of cobalt-doped nickel phosphide with high electrochemical performance
Authors: Wang Yifei , Wang Jing , Cui Hongtao
Published: October 2022

Although nickel-based phosphides as a promising category of electrode materials in supercapacitors have high intrinsic electrical conductivity, they still present unsatisfied electrochemical performance and cycling life so far, which is mostly attributed to the low-surface area or inappropriate microstructure. Therefore, constructing a microstructure that meets the requirements of supercapacitors is the key for improving the performance of nickel-based phosphides. In this work, we prepared the cobalt ions-doped Ni2P with a nanosheets-self-supported nanostructure by phosphating its precursor of cobalt ions-doped nickel hydroxynitrate. Ascribed to appropriate microstructure and elevated electrical conductivity, the cobalt ions-doped Ni2P exhibits high electrochemical and cycling performance. The cobalt ions-doped Ni2P not only shows high specific capacity of 1150.0 C g[Formula: see text] at the low current density 2.5 A g[Formula: see text], but also exhibits excellent high-rate performance about the capacity retention of 53% at high current density of 49.1 A g1, attributed to its nanosheet morphology and elevated electrical conductivity. By virtue of the nanosheets-self-supported structure, the cobalt ions-doped Ni2P also shows high cycling performance on capacity retention of 81% for 10,000 charge-discharge cycles. The high performance of cobalt ions-doped Ni2P obtained from electrochemical measurement confirms its prospect as a candidate electrode material for advanced application in supercapacitors.