bluuebunny/crossref_metadata_2025 huggingface dataset:
FUNCTIONAL AND STRUCTURAL CHANGES IN THE RAT THYMUS INDUCED BY DIFFERENT DOSES OF ENDOCRINE DISRUPTOR
Authors: Timokhina E. , Yaglova N. , Obernikhin S. , Yaglov Valentin
Published: May 2024

In recent years, there has been a significant increase in the number of diseases associated with impaired functioning of the immune system in the world. One of the main reasons for this can be considered environmental pollution by endocrine disruptors. The most common disruptor on the planet is DDT. Its ubiquitous content in food, water and soil is noted, which makes the study of the effect of its background doses on the body extremely relevant. Systemic consumption of low doses of the disruptor DDT leads to significant changes in the structural and functional characteristics of the rat thymus, which are manifested by increased death of lymphocytes and reticuloepitheliocytes, in the mechanisms of death of which the p53-dependent pathway of apoptosis is involved, as well as a decrease in the proliferative activity of thymocytes, i.e., it is capable of having an immunotoxic effect on the body. These data show that the maximum permissible levels of DDT in food are not safe for the body's immune system.
INTERACTION OF LIPOPOLYSACCHARIDE-BINDING PROTEINS WITH VARIOUS FORMS OF LIPOPOLYSACCHARIDES
Authors: Naberezhnykh G. , Davydova V. , Soloveva T.
Published: May 2024

Lipopolysaccharide-binding proteins from two common jellyfish species Aurellia aurita and Ropelema asamushi were isolated and purified, and the interaction of lipopolysaccharides (LPS) of various structural types with LBP was studied. By inhibiting the interaction, it was found that both proteins specifically bind to the lipid and core fragments of the LPS molecule. There are two types of binding sites in LBP with Kd = 3,28 × 10-6 M and Kd = 0,13 × 10-6 M (for the protein from A. aurita) and
Kd = 3,66 × 10-6 M and Kd = 0,27 × 10-6 M (for protein from R. asamushi). It has been shown by dynamic light scattering that the binding of LBP to R-LPS leads to the dissociation of LPS micelles. The sizes of LPS aggregates decrease from 200 nm to 25–30 nm in the composition of LPS–LSB complexes. The data of electrokinetic measurements indicate the neutralization of the negative charge of Rd-LPS (-42,2 mV) in the LPS-LSB-R. asamushi complex up to -4,4 mV. S-LPS micelles from E. coli do not disaggregate upon binding to LBP, which is apparently due to the shielding of lipid A by O-specific chains in the S-LPS molecule. The binding of LPS to LBP may affect their endotoxic properties.
ACTION OF EXTRACTS FROM ARTEMİSİA L. ON THE PLASMATIC MEMBRANE UNDER STRESS CONDITIONS
Authors: Babayeva G. , Musayev N.
Published: May 2024

Plant bioactive compounds are supposed to be the modifiers of structural-functional properties of cell plasma membrane under HM contamination. To test a protective effect of extracts from Artemisia L. species, possessing high adaptive potential to different soil contaminations, on electrical properties of algae cells under HM treatments was the aim of the present work. Extracts from Artemisia plants were isolated from above-ground parts of A.scoparia and A.szovitsiana by acetone hydrolyzation. Microelectrode techniques were used to study the regularities of change of membrane potential and membrane resistance of Chara gymnophylla and Nitella flexilis plasmalemma under influence of Cd, Cu, Zn, Pb and the extracts from Artemisia species. Statistically reliable hyperpolarizing effect of A.szovitsiana and A.scoparia extracts in relation to Zn and Pb was revealed, respectively. Elimination by extracts a decrease of membrane conductivity caused by Cd and Zn and also an increase of conductivity by Cu was determined. Though a high HM accumulation capacity of Artemisia L. species is noticed to not connect with protective effect of their extracts on membrane conductivity, they can be a potential source for the searching new chemical compounds which are capable to induce the plant tolerance to stress impacts.
INFLUENCE OF SOLUTIONS OF HYDROGEN PEROXIDE OF DIFFERENT COMPOSITIONS ON THE SEEDS GERMINATION
Authors: Sergeychev K. , Lukina N. , Apasheva L. , Budnik M. , Ovcharenko E.
Published: May 2024

A method has been developed for producing pure hydrogen peroxide without admixture of NOx by replacing the nitrogen medium stabilizing the flare microwave discharge with water vapor when distilled water and its vapor at atmospheric pressure are treated with pure inert argon plasma. The dynamics of seed germination and development of cucumber seedlings in pure solutions of hydrogen peroxide, in solutions of medical 3% hydrogen peroxide stabilized with sodium benzoate, and in distilled water in the control were studied. The concentrations of hydrogen peroxide solutions in the range from 0,1 mg/l to 10 mg/l were used. Cucumber seeds «Competitor» with reduced germination (the result of long-term storage) were selected as a test object. Seeds of 30 pieces were placed in Petri dishes on filters, moistened once in the experiment with the studied solutions, and in the control with distilled water. It is shown that the germination of seeds and the development of seedlings in pure solutions of hydrogen peroxide reaches 95% at a concentration of hydrogen peroxide of 1,7 mg/l, while when using medical peroxide, the same indicator was 75% at a concentration of 0,1 mg/l. Higher concentrations of medical peroxide gave the worst result, in particular, concentrations of 3,3 mg/l and 10 mg/l led to inhibition of the seed germination process and showed the worst result.
Rasionalitas Pangilang Saka dalam Aktivitas Usaha Gula Merah pada Masyarakat Nagari Bukik Batabuah Kabupaten Agam
Authors: Jannah Miftahul
Published: May 2024

This study discusses the rationality of pangilang saka in palm sugar business activities, including the work activities of pangilang saka and toke, the classification of pangilang saka, the production process to the packaging and distribution of palm sugar, and the rational considerations of pangilang saka. The research subjects were pangilang saka, who used to sell their brown sugar to the traditional market but now prefer to sell their brown sugar to toke. Toke was chosen based on their rational considerations. To obtain data, seven informants and three observers were taken. This number is considered to represent the others. The research used a qualitative research method with a descriptive approach that aims to describe the rationality of pangilang saka in brown sugar business activities. Data collection techniques were carried out by observation, in-depth interviews, document studies, and literature studies. The research findings show that pangilang saka in Nagari Bukik Batabuah have behaved rationally, which initially pangilang saka sold their brown sugar production to the traditional market, but now they sell their brown sugar production to toke. The selected toke also uses rational considerations, namely: choosing a toke based on the similarity of location; choosing a toke based on a mutually beneficial relationship; and choosing a toke based on a higher selling price.Abstrak: Kajian ini mendeskripsikan tentang rasionalitas pangilang saka dalam aktivitas usaha gula merah yang mencakup aktivitas kerja pangilang saka dan toke, klasifikasi pangilang saka, proses produksi hingga pengemasan dan distribusi gula merah, serta pertimbangan-pertimbangan rasional pangilang saka. Subjek penelitian adalah pangilang saka, di mana dulunya mereka menjual hasil produksi gula merah ke pasar tradisional kini lebih memilih menjual hasil produksi gula merah kepada toke. Toke dipilih berdasarkan pertimbangan-pertimbangan rasionalnya. Untuk mendapatkan data diambil tujuh informan pelaku dan tiga informan pengamat. Jumlah ini dianggap dapat mewakili yang lainnya. Penelitian yang dilakukan menggunakan metode penelitian kualitatif dengan pendekatan deskripstif yang bertujuan untuk mendeskripsikan tentang rasionalitas pangilang saka dalam aktivitas usaha gula merah. teknik pengumpulan data dilakukan dengan observasi, wawancara mendalam, studi dokumen, dan studi literatur. Temuan penelitian menunjukkan bahwa pangilang saka di Nagari Bukik Batabuah sudah bersikap rasional, yang pada awalnya pangilang saka menjual hasil produksi gula merah ke pasar tradisional, namun sekarang sudah menjual hasil produksi gula merah ke toke. Toke yang dipilih juga menggunakan pertimbangan rasional, yaitu: memilih toke berdasarkan kesamaaan lokasi bermukim; memilih toke berdasarkan hubungan saling menguntungkan; dan memilih toke berdasarkan harga jual yang lebih tinggi.
THE RELATIONSHİP BETWEEN RESTLESS LEGS SYNDROME AND VİTAMİN B12 LEVELS IN PREGNANCY
Authors: AŞKIN YURDAKUL DUDU , Çimşir Meral Tuğba , Savaş Hasan Basri
Published: May 2024

ABSTRACT Backgrounds: Restless legs syndrome is a disorder which increases in pregnancy. Symptoms that occur during pregnancy can become permanent. Also the biochemıcal parameters can effect the sypmptoms of RLS. This study aimed to
investigate the possible relationship between restless legs syndrome and Vitamin B12 Results:Alanya Alaaddin Keykubat University Education and Research Hospital was included in our randomly selected 100 pregnant women that applied
to the Gynecology and Obstetrics outpatient clinic. Pregnant women were divided into two groups: one group with restless leg syndrome, and one group without. It was investigated whether there is a statistically significant difference
between the Vitamin B12 levels between the two groups. This study revealed that patients with RLS had significantly higher serum Vitamin B12 levels in comparison to controls Conclusıon: This study found no significant relationship
between vitamin B 12 and RLS, it is essential to examine the possible relationship in larger patient groups in terms of evidence-based medicine
MODEL PERAMALAN JUMLAH TANGKAPAN IKAN KAKAP YANG DIDARATKAN DI PPI OEBA KUPANG NUSA TENGGARA TIMUR
Authors: Edo Sri Imelda , Nalle Mikson Metraim Daniel
Published: May 2024

Snapper is one of the economically important fish targeted by fishers in the island of Timor. Domestic and foreign markets for fillet and fresh snapper is considerably large. The export volume in 2021 was 4,172,056 kg, and the total value reached 12,452,211 USD. Along with the increasing snapper production in Kupang City and NTT, it is necessary to forecast the future snapper production. Thus, it can be a reference for policy makers in the region in designing fisheries development. This study aims to produce forecasting model for snapper catches at PPI Oeba Kupang. This research applied Autoregressive Integrated Moving Average (ARIMA) and Seasonal Autoregressive Integrated Moving Average (SARIMA), as a forecasting method. The data of snapper production analyzed in this study consisted of 72 months, started from January 2016 to December 2021. Data were obtained from the UPT of the Department of Marine and Fisheries of NTT Province at PPI Oeba Kupang. Data have a non-stationary pattern to the variance, hence a logarithmic transformation is needed, as well as seasonal differences analysis. However, there is no need for non-seasonal differences since the data are stationary with respect to the mean. The results of the identification of the Autocorrelation function and Partial Autucorrelation function Plots are ARIMA models with seasonal factor period 4, ARIMA (P,D,Q) = (1,0,1), while the SARIMA order (P, D, Q) = (2,1,1)4. Based on parameter testing, verification, examination, and testing of suitable models, the best model obtained was (0,0,1)(2,1,1)4.
Keywords:       Autoregressive Integrated Moving Average, focecasting model, Seasonal Autoregressive Integrated Moving Average, Snapper.
POTENSI LESTARI DAN STATUS PEMANFAATAN IKAN TONGKOL (Auxis thazard) DI PERAIRAN MALUKU TENGAH
Authors: Waileruny Welem , Saidi Rifan , Matrutty Delly DP
Published: May 2024

Fishery resources are open access and often considered as common property. This can lead to a decrease in the quality of fish resources and economic rents. This study aims to calculate the maximum sustainable yield (MSY) and to determine the exploitation status of mackerel tuna (Auxis thazard) in Central Maluku Regency water. Analysis of MSY was conducted using the Walter Hilborn and Schaefer models. It is revealed that the main fishing gear for mackerel tuna fishing in Central Maluku is purse seine which in the MSY analysis are classified as standard fishing gear. The results show that the maximum hMSY and eMSY are 17,329 tons/year and 3,055 trips/year respectively. The utilization status is at the fully-exploited level.
Keywords:       Fully-exploited of mackerel tuna, mackerel tuna, maximum sustainable yield, production of mackerel tuna, model Schaefer.
MODIFIKASI DINDING BUBU LIPAT UNTUK MELOLOSKAN RAJUNGAN YANG BELUM LAYAK TANGKAP
Authors: Susanto Adi , Sutrawan Nurdin Hery , Jayanudin  , Irnawati Ririn , Hamzah Asep , Supadminingsih Fahresa Nugraheni , Syafrie Hendrawan , Azkia Lana Izzul , Sucilawati Mumung , Adisaputra Divandra Yogi , Hikmatyar Alfito Dicky
Published: May 2024

Increasing of fishing pressure poses a serious threat to the sustainability of blue swimminng crab resources. Trap design modifications are needed to improve size selectivity and to release under size crabs. This study aimed to determine the type of wall modification of collapsible trap that is effective in excluding under size blue swimming crab. Laboratory observations were conducted using four escape vents treatments and three different mesh sizes. The escape gap used are rectangular, square, circular and oval respectively. Moreover, the mesh sizes used are 2.0 inches, 2.5 inches and 3.0 inches. Descriptive analysis and scoring were used to determine the most effective type of wall trap modification to be used in the blue swimming crab fishing. The results showed that the rectangular escape gap has better effectiveness than other shapes with the percentage of crabs that pass through at 86.7%. The wall modification using a 3.0-inch mesh size had better performance than the other modification types with a total score of 19. Collapsible trap with a 3.0-inch mesh wall was able to escape 86.7% of the crabs with an escape time of only 11.2 seconds and an average escaped crab carapace width of 78 mm.
Keywords: Collapsible trap, escape gap, environmentaly-frendly fisheries, mesh size of trap wall
Pengaruh Lingkungan Kerja dan Stres Kerja terhadap Kinerja Karyawan
Authors: Zuliatun Nopita , Abidin Zainal , Wahyulina Sri , Magfirahti Ranggaini
Published: May 2024

This research is entitled the influence of the work environment and work stress on employee performance at the East Lombok Regency Personnel and Human Resources Development Agency office. Aims to determine the influence of the work environment and work stress on employee performance. The type of research used is associative research with a quantitative approach. The data collection method used is the census method. The population and respondents in the research were 52 employees of the East Lombok Regency Personnel and Human Resources Development Agency Office. The analytical tool used is Multiple Linear Regression using SPSS version 20. The results of the analysis show that: (1) The work environment has a positive and significant effect on the performance of employees at the East Lombok Regency Personnel and Human Resources Development Agency Office. (2) Job Stress has a negative and significant effect on the performance of employees of the East Lombok Regency Personnel and Human Resources Development Agency Office
APLIKASI ALAT BANTU ERGONOMIS PADA KERJA MANUAL BERDASARKAN KAJIAN ERGO-MECHANICAL UNTUK PETANI KECIL
Authors: Bawa Susana I Gede , Perdana Putra I Ketut
Published: May 2024

Using traditional tools and manual work by small farmers in rural and developing areas is routine in processing agricultural land, especially planting plant seeds. This working model includes moderate to severe workload due to additional workload, namely sunlight when planting. In addition, work is carried out with non-ergonomic work postures, namely non-natural work postures. This causes musculoskeletal complaints to workers due to the non-harmonious tools with workers. Workers' productivity will decrease and have the potential to reduce the quality of life of small farmers themselves. To help the manual work of small farmers to create effective, comfortable, safe, healthy, efficient, and sustainable jobs, an ergo-mechanical application is needed to design work tools. This application is based on studies conducted on the design of work tools from several libraries or research results. The ergo-mechanical study is an integrated system that applies ergonomic and mechanical principles. The ergo-mechanical application produces ergonomic work tools that are comfortable to use by workers, and technical standards include material, product, and service requirements. Mechanically, the application through technical drawings, mechanical planning, and work tool materials to get a strong, lightweight, and safe work tool from hazardous substances, according to technical specifications. Technical standards are related to data sheets or specifications that describe the technical characteristics of a work tool. On the specifications of the work tool design, specifications can be added that the work tools are ergonomic. Ergonomic work tools can produce effective, comfortable, safe, healthy, and efficient work. This results from the compatibility between work tools and workers or the harmonious work tools with workers. Ergo-mechanical creates comfort in work that affects the increase in productivity and quality of life for workers.
Model Based Clustering for Regency/City Grouping Based on Community Welfare Indicators in North Sumatra
Authors: Hasibuan Muhammad Afif Fauzi , Cipta Hendra , Dur Sajaratud
Published: May 2024

This thesis aims to apply model-based clustering in grouping regencies/cities in North Sumatra based on Community Welfare Indicators to determine the number of groups (clusters) formed based on community welfare indicators in regencies/cities in North Sumatra and to understand the level of community welfare from this grouping in planning and managing community welfare in regencies/cities in North Sumatra, with the hope of achieving equal welfare in every region. The research method used is Model-Based Clustering, which uses 5 research data variables: HDI, Poor Population, Unemployment Rate, GDP, and Health. In this millennial era, the assessment of community welfare requires more attention. Rapid social, technological, and environmental changes have created new dynamics that can affect community welfare. The evaluation of community welfare is not only limited to economic parameters but also considers health, unemployment, and other factors. By using Model-Based Clustering, it is possible to determine the optimal number of groups (clusters) from various and possibly correlated variables, and the results are easier to understand, making the analysis and understanding of the results easier. Readers can learn about the level of community welfare, and the community and government can evaluate their welfare for future improvements. The research results show that among the groups of regencies/cities formed, five cities consistently show lower Gross Regional Domestic Product (GDP) and Human Development Index (HDI) than other cities. Therefore, a sustainable approach is needed to improve these cities' economic conditions and social welfare.
Propagation of the Vanda helvola Orchid In Vitro
Authors: Muharyati Yully , Setiyadi Muhammad Wahyu , Khatimah Ainul , Ardiansyah Ardiansyah
Published: May 2024

Orchids are more economical and tall than plants and other decorations. One of the orchids cultivated is the Vanda orchid. Seed orchid size is small and does not have endosperm, so it is not easy to germinate in nature, so tissue culture is one multiplication orchid in amount a lot and a short time. This study aims to know the growth of the seed orchid Vanda helvola on different media for 12 days after plant. Seed orchid V. helvola grown on modified Murashinge and Shoog (MS), modified Vaccin and Wend (VW) media and organic media. The research was conducted at the Tissue Culture Laboratory of the UPT Center for Food Crops and Horticulture (BBIPTH), Luwus Tanaban, from February to May 2023. The research method used was observation and experimentation, and the research design used RAK (group random design). Research shows modified MS Media, modified VW and organic capable change seeds orchid V. helvola. Modified MS and modified VW media can induce seed orchid V. helvola germination, and MS media can induce formation protocol.
An Ethnoscience Exploration of Terbang Gembrung Percussion From Kampung Naga, West Java and the Potential as Local Context in Physics Education
Authors: Sarah Lia Laela , Liliawati Winny , Sriyati Siti
Published: May 2024

This research aims to explore the ethnoscience of the Terbang Gembrung percussion instrument of the indigenous community in Kampung Naga, Tasikmalaya, West Java, and its potential as a local context in physics education. The Terbang Gembrung percussion instrument of Kampung Naga employs an acoustic membrane of goat leather with an air column of albasia or manglid wood. The research methodology encompasses qualitative descriptive methods, including literature study and interviews, as well as observation methods involving the measurement of sound frequency generated using the Decibel X smartphone application under conditions where the instrument produces typical sound. The Terbang Gembrung tradition holds religious value and is commonly performed during significant celebrations such as Eid al-Fitr, Eid al-Adha, and other religious festivities. Based on the observation results, it was found that four types of percussion instruments produce sound frequencies at four harmonic levels according to the membrane size. The first harmonic has a frequency of approximately 199.0 Hz, the second harmonic around 211.5 Hz, the third harmonic approximately 231.5 Hz, and the fourth harmonic around 261.0 Hz. The design of the percussion instrument is in the form of a half-spherical cone, with the cross-sectional area decreasing from the membrane to the end of the air column. The potential application of science principles to the Terbang Gembrung percussion instrument makes it a cultural artifact that can serve as a local context in physics education at the high school level, focusing on the topics of sound waves, especially sound intensity and sound frequency.
Métodos de cría y reproducción de ácaros depredadores del orden Mesostigmata
Authors: Esquivel-Ayala Blanca Alicia , Chaires-Grijalva Martha Patricia , Montañez-Hernández Silvano , Lara-Chávez Blanca Nieves , Vargas-Sandoval Margarita
Published: May 2024

Debido al uso irracional de productos químicos para el control de plagas en los cultivos intensivos, se han disminuido de manera alarmante la diversidad de comunidades de organismos benéficos, tal es el caso de los ácaros depredadores del orden Mesostigmata. Estos arácnidos han tomado relevancia agrícola debido a que, la mayoría de sus miembros presentan hábitos alimentarios zoofágicos y regulan de manera natural poblaciones perjudiciales de insectos, nematodos y otros ácaros que habitan las plantas. De manera regular, desde hace más de 40 años se introducen los ácaros depredadores para los trabajos de biocontrol y se estima que más de 60% de los programas utilizan estos organismos; sin embargo, los productos comerciales disponibles están limitados a unas pocas especies, las cuales varían en efectividad según las condiciones del cultivo, disponibilidad de presas y competencia de nichos con otros organismos también depredadores, además, su producción está resguardada bajo secreto empresarial en la mayoría de los casos. Con esto, se abre la oportunidad para explorar especies nativas o incluso ya comercializadas, con el fin de evaluar su capacidad depredadora a nivel de investigación o como herramientas habituales para la regulación de plagas, un primer reto para este fin es la propagación y los métodos de cultivo. Los métodos para cultivar ácaros se pueden dividir en dos: mantenimiento sobre plantas y en confinamiento, aunque cada técnica se ha desarrollado para una especie en particular o un fin determinado, el conocer su diseño básico, promete acercarnos a una nueva línea de estudio para su introducción y reintroducción en los sistemas agrícolas.
PROPOSTA DE UMA ANALISE DE REGRESSÃO PARA UM PROCESSO DE SOLDAGEM COM ARAME TUBULAR PULSADO ATRAVÉS DOS SINAIS DE CORRENTE E TENSÃO
Authors: Roberto Sartori Moreno João , Caetano Neves Alisson , Alves Correa Celso , Fracaro Souza Gonçalves Janaina
Published: May 2024

Este estudo propõe a análise estatística de soldas de revestimento utilizando processo de soldagem com arame tubular e corrente contínua pulsada (P-FCAW), com análise de variância para analisar a eficácia de modelo de regressão de primeira ordem e relacionar os valores obtidos de corrente média, tensão média, potência média, largura e reforço. Corpos de prova de aço SAE 1020 foram usados para receber cordões de revestimento de arame metálico tubular em inoxidável martensítico 410 NiMo. Alguns parâmetros de soldagem foram mantidos constantes como a composição do gás e vazão, quantidade de cordões, corrente de pico e tempo de pico entre outros, enquanto corrente média, frequência de pulsação, velocidade de soldagem e DBCP são variados em três níveis, conforme método de TAGUCHI (L9) visando reduzir o número combinações. Portanto, a análise de variância foi aplicada nos resultados e estatisticamente a corrente média e a distância bico de contato peça foram as variáveis que mais influenciaram as respostas obtidas. O coeficiente de determinação ou R2 da regressão linear simples para quatro modelos foram acima de 80%, enquanto que nos sinais elétricos ficou entre 85 e 97%. A maior largura obtida foi de 11,49 mm na corrente média de 230 A, velocidade de soldagem de 300 mm/min, distancia bico de contato peça de 30mm e frequência de pulsação de 30,30Hz.
Santidade e Pecado no Corpo Místico
Authors: Weber Aloísio
Published: May 2024

Neste trabalho tratamos unicamente da santidade e do pecado, não considerados em si, mas só no conjunto do C. M. (Corpo Místico). Para conseguir êste fim é mister investigar, primeiramente, se pode ou não haver pecado, privação de santidade, nos membros do C. M. Porque, à primeira vista, estes dois conceitos parecem excluir-se mutuamente. A fim de proceder metodicamente, procuraremos, primeiro, provar brevemente a possibilidade do pecado nos membros do C. M., em seguida tentaremos dar a explicação teológica deste fato tão estranho, para depois explicar e circunscrever a nefasta influência do pecado dentro do organismo do C. M. Para conseguir isto, será preciso confrontar, continuamente, a influência do pecado com a da santidade...
Microstructure-Linked Mechanical Properties of P91-Incoloy 800HT Dissimilar Metal Welds
Authors:   American Welding Society, BHANU VISHWA , GUPTA ANKUR , PANDEY CHANDAN
Published: May 2024

Dissimilar metal welds (DMWs) between P91 steel and Incoloy 800HT® using shielded metal arc welding (SMAW) with ENiCrCoMo-1 filler electrode were characterized in detail. The impact of multiple weld passes on microstructure in the heat-affected zone (HAZ) and weld fusion zone (WFZ) was thoroughly investigated. Postweld heat treatment (PWHT) impacts on mechanical characteristics and microstructure were also observed. The DMW was observed with heavy C, Cr, and Mo microsegregation in the WFZ, which deteriorated mechanical strength. The microstructural changes directly affected the mechanical behavior of the DMW. The ultimate tensile strength of the weld fusion zone was low at 576 MPa compared to the base metals’ strength. The tensile specimens failed in the IN 800HT base metal and WFZ. The WFZ had significant microsegregation near the solidified grain boundaries (SGBs). The metallurgical heterogeneity in the WFZ caused the formation of localized stress zones, which directly affected the mechanical behavior of the WFZ. The carbide particles influenced the microhardness in the WFZ and P91 HAZ regions. The PWHT successfully homogenized the microhardness in the WFZ and P91 HAZ regions. The impact toughness decreased to 64 J from 82 J after PWHT due to precipitation at SGBs and its coarsening. The SMAW process involves multiple thermal cycles during welding. The deposition of filler metal in multiple welding passes created uncontrolled variations in the solidification behavior of the WFZ. Microsegregation had a detrimental impact on the microstructure and mechanical properties of the P91 and IN 800HT dissimilar metal welds.
Bacteriological profile of community peritonitis in adults at Mohammed VI university hospital
Authors: ELAASSRI Soukaina  , Tazi Saad  , Babokh Fatima  , ELKHANNOURI Imane  , Benhoumich Taoufik  , Amrani Asmaa  , Soraa Nabila
Published: May 2024

A good analysis of intraperitoneal bacteriological results constitutes the basis of therapeutic consideration. The objective of this work is to report the main epidemiological and bacteriological characteristics of community-acquired peritonitis in adults at the Mohammed VI University Hospital of Marrakech. This is a retrospective descriptive study carried out in the microbiology laboratory of Arrazi hospital at Mohammed VI University Hospital in Marrakech over a period of seven years from January 1, 2017 to December 31, 2023 including all community peritonitis documented in our hospital. The cytobacteriological study was carried out according to conventional methods. During the study period (2017-2023), 503 documented peritonitis were collected, The profile of the incriminated germs was dominated by Escherichia coli (48.9%) followed by Streptococci (18.3%), 8% of Pseudomonas aeruginosa and 18.5% for other Enterobacteria. Our results showed that E coli becomes increasingly resistant to the combination of amoxicillin acid clavulanic which is the antibiotic commonly used in our context, this leads us to review the antibiotics prescribed probabilistically in our context for the management of peritonitis community.
Security protocols in healthcare: A comprehensive study of AI-Enabled IoMT
Authors: Swetha Singiri  , Naga santhosh reddy vootukuri  , Siri Chandana Katari
Published: May 2024

The Internet of Medical Things IoMT has driven a paradigm shift in the way things have been done traditionally within medical Healthcare practices and this is evidence that Smart Personal systems (Health Care) are shaping up with mighty forces. By merging these technologies, IoT has transformed data communication and provided the means to directly interconnect medical devices and sensor systems. The use of advanced technologies like Artificial Intelligence( AI), Machine Learning, Deep Learning, and Federated Learning has highly equipped and transformed the IoMT’s performance. These integrations also raise concerns on data privacy and security, and addressing these challenges become more important as without proper security and privacy measures people can face serious disruption both online and offline leading to upcoming catastrophes already waiting at its end line. This chapter looks into the intricacies of a highly secure communications system powered by AI, specifically in the age where disasters like COVID-19 [10], emphasizes the need for increased security on data transmission as well as storage. IoMT has wide applications for integrating remote patient monitoring, enhancing user satisfaction and interdimensional hospitalization rates, we delve into how IoMT works in conjunction with machine learning, particularly federated Learning intends to address any possible concerns. The chapter begins with IoMT systems, including IoMT ecosystems, implantable medical devices IMDs, and Internet-worn gadgetry. Special attention is given to the AI-powered Intrusion Detection Systems (IDSs) in IoMT environments, while network security remains the research focus helping practitioners to implement safety measures enterprise-wide; analysis, comparison, and evaluation all encompass machine learning, deep learning mechanisms as precautions against potential attacks. We will also consider another study on the services of an AI-provisioned lightweight protocol communication system that ensures data authenticity and responds to diverse security implications in IMD. The chapter makes a U-turn by alluding to internet wearable devices, pointing out federated learning and blockchain reinforcements that indicate the need for an integrated framework. The amalgamation of future technologies supports the ethical and secure integration of IoMT. Collaboration, as a guiding principle, compels healthcare practitioners and policymakers to partner efficiently to guide the future where the security of health is ever easier. In the end, a summary of modern ethical and regulatory paradigms in IoMT is provided, emphasizing that there could be an urgent need for new laws.
Perceived level of understanding in writing action research of clarin south district elementary teachers: Basis for capacity building
Authors: MYLENE AMOR N. BADAJOS  , DR. DENMARK S. MACALISANG
Published: May 2024

Writing action research has become central for effective and productive learning to happen. This research aimed to determine the perceived level of understanding in writing action research among the 124 public elementary teachers from the 14 schools in Clarin South District, Division of Misamis Occidental. Frequency Count and Percentage, Weighted Mean, Standard Deviation, Kruskal-Wallis H test, and Mann-Whitney U Test were used to quantify data on the perceived level of understanding in writing action research and its significant differences when grouped according to profile. Results revealed that most of the teachers were female, 41 to 50 years old, had earned master’s degree units, and had been working as Teacher I for less than 10 years. The perceived level of understanding on writing action research among teachers of Clarin South District was generally very high (GWAM=3.37) and did not significantly differ when grouped according to their profile. Therefore, teachers were committed to ongoing professional development and had the skills and knowledge required to conduct action research. Thus, it is suggested encouragement and support for professional development, and implementation of action research training and support for collaborative research.
New clinical treatment plan for acute lymphoblastic leukemia after whole genome sequencing: An update of the development of new technologies for genome editing
Authors: Alok Bandyopadhyay
Published: May 2024

Acute lymphoblastic leukemia (ALL) is now being reclassified into newly identified subtypes due to genetic abnormalities, Philadelphia chromosome‐like B‐lineage ALL is one of the new high‐risk subtypes characterized by genetic alterations that activate various signaling pathways, including those involving cytokine receptors, tyrosine kinases, and epigenetic modifiers. Philadelphia chromosome‐like ALL is essentially heterogeneous; however, deletion mutations in the IKZF1 gene encoding the transcription factor IKAROS underlie many cases as a key factor inducing aggressive phenotypes and poor treatment responses. WGS (whole genome sequencing) studies of ALL patients and ethnically matched controls also identified inherited genetic variations in lymphoid neoplasm‐related genes, which are likely to increase ALL susceptibility. On the contrary, Genome editing technologies offers new opportunities for tackling diseases, and genome-editing tools such as CRISPR-Cas9 are an important means of advancing functional studies of ALL through the incorporation, elimination, and modification of somatic mutations. These findings are directly relevant to clinical hematology, and further studies on this aspect could contribute to accurate diagnosis, effective monitoring of residual disease, and patient‐oriented therapies.
Role of Pathyapthya and lifestyle management in Parikartika (fissure-in-ano): A literature review
Authors: Vd. Ashishkumar Ajaykumar Mishra  , Vd. Vijay Rudrappagol
Published: May 2024

In this present competitive world, due to sedentary life style, irregular and inappropriate diet, prolonged sitting work, psychological disturbances causing disturbances in digestive system (derangement of jatharagani/power of digestion) which leads to constipation along with anorectal pathology, parikartika (fissure-in-ano) is one of them. Acharya’s have emphasized the significance of preventive elements and distinct records about Dincharya(each day), Ritucharya(healthy seasonal regimen), Ratricharya(healthy night regimen) etc. This text particularly makes a speciality of preventive measures for the Anorectal illnesses with appropriate dietary recommendations and every day regimens. The Ayurveda particularly focuses on the preventive technique for the sicknesses. This text focuses around preventive and promotive measurements for the anorectal diseases such as parikartika (fissure-in-ano) which includes appropriate nutritional administrations, manner of lifestyles style regimes, Yogic sporting activities and pathya-Apathya. The little modifications in way of life can alternate the substance of the illness and the patient can be pretty benefited. The GUDA (anal) region is the essential marma of the body, if any infection related to this region can be tremendously fatal, consequently it must be ensured with complete endeavors to preserve a strategic distance from such illnesses.
Radiotherapy of epithelioid hemangioendothelioma of the posterior fossa
Authors: Lionel Eric Francis Edimo  , Awa Sadikh Badiane  , Ndeye Fatou Kane Ba  , Mamadou Moustapha Dieng  , Pape Macoumba GAYE
Published: May 2024

Epithelioid hemangioendothelioma is a widespread vascular cancer that is infrequently detected within the skull. Frequently seen in young individuals and typically treated with surgery at first. Interferon and radiotherapy are commonly used as treatments, especially during the adjuvant phase. Prognostic factors are decided by the initial treatment and the type of histology. We present a case of a patient who received adjuvant radiotherapy following a partial resection in our department. After 4 months of monitoring, we saw a significant improvement in the neurological symptoms, however the right central facial paralysis persisted primarily because the patient did not consistently attend motor physiotherapy sessions for facial re-education.
Acupuncture for low back pain and migraine
Authors: Maria I. Dalamagka
Published: May 2024

Acupuncture has been increasingly used as an integrative or complementary therapy for pain. It is well-tolerated with little risk of serious adverse effects. Traditional acupuncture and nontraditional techniques, such as electroacupuncture and dry needling, often result in reported pain improvement. Acupuncture is an ancient Chinese medical practice that involves inserting thin needles into specific points on the body. Acupuncture can be used to treat a wide range of health conditions, including migraines and low back pain. Acupuncture works by stimulating the nervous system, releasing endorphins and increasing blood flow to the affected area. Acupuncture may also help to reduce inflammation and improve circulation in the body. Controlled trials have been published on pain syndromes, such as acupuncture for acute and chronic low back pain, knee osteoarthritis, headache, myofascial pain, neck pain, and fibromyalgia. For some conditions, enough data are available for systematic evaluations or meta-analyses. Acupuncture may provide modest benefits in the treatment of chronic low back pain, tension headache and chronic headache, migraine headache prophylaxis, and myofascial pain.The benefits of acupuncture for people with back pain has been well researched compared to many other conditions, with more higher quality clinical trials. This systematic review will focus on the use of acupuncture and its role in the treatment of low back pain to help better guide physicians in their practice. To determine the effects of a policy of ‘use acupuncture’ on headache, health status and chronic pain. The results of this study will determine if acupuncture, alone or as an adjunct to pharmacotherapy provides effective, safe and acceptable pain relief for patients.
The Mediating Role of Trust and its Relationship with the Perception of Convenience and Transparency on User Satisfaction of Electronic Procurement Services
Authors: Baskara Abdullah , Nuryakin Nuryakin , Handayani Siti Dyah
Published: May 2024

Background – In the current 4.0 industrial revolution, the government is required to be able to create innovations including in public services based on information and communication technology. In addition, E-procurement is a form of innovation based on e-government which is almost entirely accomplished by making use of information and communication technology.
Aim – This study aims to determine the effect of perceived convenience and transparency on Electronic Procurement Services or LPSE user trust, the effect of ease, transparency and trust on LPSE user satisfaction, the impact of trust in mediating the effect of perceived convenience on LPSE user satisfaction, and the role of trust in mediating the effect of transparency on LPSE user satisfaction.
Design / Methodology / Approach – Respondents in this study were businessmen and consultants who had participated in tenders within the Ministry of Religion D. I. Yogyakarta as many as 180 respondents using the accidental sampling technique. A quantitative method of SEM and AMOS was applied in the study.
Findings – From the tested and collected data, the results show that ease and transparency perceptions affect positively and significantly on user trust. Furthermore, the feeling of convenience, transparency and trust bring a favorable and significant impact on user satisfaction. User satisfaction is unaffected by user perception through trust as an intervening variable.
Research implication – Transparency has no impact on customer satisfaction through trust as an intervening variable.
Limitations – Further research taking independent variables other than perceptions of convenience, transparency and trust.
Analisis Faktor Yang Mempengaruhi Kejadian Fraud Pada Organisasi Perangkat Daerah Kabupaten Manggarai
Authors: Yuliani Priska , Ardini Lilis , Kurnia Kurnia
Published: May 2024

Background - Fraud is an interesting issue to discuss and it is necessary to study cases that often occur in organizational management areas such as regional apparatus organizations. Some Fraud cases occur in Indonesia due to failures in the accountability process of the government such as failed leadership styles, inappropriate compensation and individual morality.
Objective - To examine the effect of leadership style, compensation suitability and individual morality on Fraud in Regional Apparatus Organizations in Manggarai Regency, East Nusa Tenggara (NTT).
Design / Methodology / Approach - Using quantitative methods with a questionnaire distributed to 100 employees from 20 OPDs in Manggarai Regency, who are authorized to use the budget as respondents who are eligible to be sampled. The sampling technique in this study used purposive sampling technique with the data analysis method used was path analysis with the sobel test processed by SPSS version 26.
Results and Discussion - Individual behavior, leadership style, suitability of compensation, and individual morality have no influence on unethical behavior, while compliance with financial rules influences unethical behavior. Leadership style, suitability of compensation, individual morality and compliance with financial regulations have no effect on the occurrence of Fraud, while internal control has a negative effect on Fraud. Unethical behavior is able to moderate internal control variables, individual morality, and compliance with financial regulations regarding Fraud incidents.
Conclusion - The unethical behavior variable can be an intervening variable in the occurrence of Fraud in the Manggarai OPD. The Manggarai Regency Government is expected to be able to prevent Fraud by considering the influencing factors and factors that mediate the occurrence of Fraud.
Research limitations - Has several limitations, namely that it was only carried out on 20 OPDs in Manggarai Regency, NTT, so that it cannot be generalized to a wider area.
PELAKSANAAN POS PEMBINAAN TERPADU PENYAKIT TIDAK MENULAR (POSBINDU PTM) DI KOTA AMBON: SEBUAH STUDI KUALITATIF DI KELURAHAN PANDAN KASTURI DAN HATIVE KECIL
Authors: Ulandari Putri , Que Bertha Jean , Titaley Christiana Rialine , Wijaya Aldo Evan , Malakauseya Maxwell L. V. , Liesay Leonardo S. , Saptenno Lidya , Hussein Anggun L. , De Lima Filda , Ohoiulun Annastasia
Published: May 2024

Posbindu PTM adalah salah satu bentuk pemberdayaan masyarakat yang dibentuk oleh pemerintah guna menanggulangi penyakit tidak menular. Walaupun demikian, dalam pelaksanaannya terdapat berbagai permasalahan yang dapat menghambat keefektifan Posbindu PTM. Penulisan merupakan hasil analisis penelitian kualitatif Fakultas Kedokteran Universitas Pattimura pada bulan November 2019 - Januari 2020. Tujuan analisis adalah mengetahui pelaksanaan Posbindu PTM. Data diperoleh hasil wawancara mendalam dan FGD informan yang berada di Posbindu PTM wilayah Puskesmas Rijali dan Puskesmas Hative Kecil serta Dinas Kesehatan Provinsi Maluku. Analisis dilakukan terhadap pelaksanaan, sumber pembiayaan, dan respon masyarakat pada masing-masing Posbindu PTM. Hasil analisis menunjukkan bahwa Posbindu PTM di Kelurahan Pandan Kasturi dan Negeri Hative Kecil telah berjalan. Terdapat beberapa hal yang perlu ditingkatkan seperti melibatkan pihak swasta dan pelatihan kader secara berkala.
KEPERCAYAAN TERHADAP KADER DALAM MENJALANKAN PELAYANAN KESEHATAN PADA POSBINDU PTM DI PULAU SAPARUA DAN KOTA AMBON
Authors: De Lima Filda Violita Ingrad , Titaley Christiana Rialine , Que Bertha Jean , Malakauseya Maxwell L. V. , Hussein Anggun L. , Saptenno Lidya , Ohoiulun Annastasia , Liesay Leonardo S. , Wijaya Aldo Evan , Ulandari Putri
Published: May 2024

Salah satu usaha kesehatan berbasis masyarakat yang dilakukan untuk menyelesaikan masalah penyakit tidak menular di Indonesia adalah Posbindu PTM. Sebagai sebuah UKBM, kader berperan sebagai pelaksana kegiatan Posbindu PTM. Keterbatasan kader terutama dalam hal pengetahuan dan keterampilan menjadi hambatan dalam melaksanakan tugasnya. Hal ini sering kali mempengaruhi kepercayaan masyarakat terhadap kader. Penelitian ini bertujuan untuk mengetahui perspektif pengambil kebijakan, masyarakat, dan kader tentang kepercayaan kepada kader dalam melakukan pelayanan kesehatan di Posbindu PTM. Penelitian kualitatif ini dilaksanakan di lima wilayah kerja Puskesmas yang ada di Kota Ambon dan Pulau Saparua pada bulan November 2019-Januari 2020. Penelitian ini melibatkan 46 informan dalam diskusi kelompok terfokus dan  43 informan dalam wawancara mendalam. Dalam penelitian ini dipeorleh beberapa alasan masyarakat meragukan pelayanan yang dilakukan kader yaitu masalah legal etik pemeriksaan oleh tenaga non kesehatan, kader tidak memiliki latar belakang pendidikan kesehatan, kader tidak percaya diri dalam melaksanakan pemeriksaan, takut kader melakukan kesalahan dalam pemeriksaan, kurangnya dukungan pengambil kebijakan dan masih kurangnya pemahaman tentang konsep penyelenggaraan posbindu. Sebaliknya, kader lebih mendapatkan kepercayaan apabila telah mendapatkan pelatihan dan tetap mendapatkan pendampingan dari puskesmas Pembina, dukungan pengambil kebijakan kepada para kader, serta masyarakat yang telah memiliki pengetahuan yang baik tugas kader di Posbindu.