bluuebunny/crossref_metadata_2025 huggingface dataset:
ANALISIS KEMAMPUAN KOMUNIKASI MATEMATIS SISWA DA-LAM MENYELESAIKAN SOAL OPEN ENDED PADA MATERI ARITMETIKA SOSIAL KELAS VII SMP
Authors: Widayanti Evi , Anggraeni Sukma Ana
Published: December 2019

Kemampuan komunikasi matematis siswa dalam menyelesaikan soal open ended yang berkaitan dengan permasalahan sehari-hari sangatlah penting. Penelitian ini bertujuan untuk mengukur, menganalisis, dan mendeskripsikan kemampuan komunikasi matematis siswa dalam menyelesaikan soal open-ended pada materi aritmetika sosial kelas VII SMP. Jenis penelitian adalah penelitian deskriptif kualitatif. Subjek penelitian ada 36 siswa kelas VII-H di SMPN 28 Surabaya dan diambil 6 siswa dari kategori tinggi, sedang, dan rendah. Teknik pengumpulan data yang digunakan adalah tes dan wawancara. Tes berupa soal open-ended materi aritmetika sosial. Wawancara untuk menganalisis kemampuan komunikasi matematis secara lisan menggunakan wawancara semi terstruktur. Subjek dianalisis berdasarkan 3 indikator yaitu: 1) menyatakan peristiwa sehari-hari dalam bahasa atau simbol matematika (IDK 1), 2) menjelaskan ide, situasi dan relasi matematik, secara lisan dan tulisan dengan benda nyata, gambar, grafik dan aljabar (IDK 2), dan 3) menganalisis dan mengevaluasi pemikiran matematis dan strategi yang dipakai orang lain (IDK 3).

Hasil penelitian menunjukkan bahwa kemampuan komunikasi matematis siswa dalam menyelesaikan soal open-ended pada materi aritmetika sosial kelas VII SMP dapat dikatakan baik, karena (1) siswa pada kategori tinggi mampu mencapai Indikator 1 (IDK 1), IDK 2, dan IDK 3, (2) siswa pada kategori sedang mampu mencapai IDK 1 dan IDK 2, tetapi kurang mampu pada IDK 3, dan (3) siswa pada kategori rendah mampu mencapai IDK 1, kurang mampu pada IDK 2, dan belum mampu pada IDK 3.
Bento Prado Jr. entre Bergson e Wittgenstein
Authors: Segatto Antonio Ianni
Published: December 2019

Meu propósito neste texto é duplo: 1) pretendo mostrar que a leitura de Bergson e Wittgenstein feita por Bento Prado Jr. é motivada por uma mesma questão filosófica, a saber: qual é o destino da ilusão transcendental kantiana na filosofia contemporânea?; 2) retomando a comparação entre os dois autores sugerida por Bento, pretendo colocar duas perguntas: será que, sob a aparente proximidade entre Bergson e Wittgenstein no tratamento da questão mencionada, não se esconde uma divergência intransponível entre esses autores? Será que, seguindo o espírito da leitura e apropriação da filosofia wittgensteiniana por Bento, não seria necessário recusar o bergsonismo em nome da concepção terapêutica de filosofia de Wittgenstein? Pretendo mostrar que ambas as questões devem ser respondidas afirmativamente. Isso coloca um problema para a reflexão de Bento sobre a questão inicial, uma vez que faz com que a apropriação simultânea de Bergson e Wittgenstein pareça inconsistente.
Dyonélio Machado como figura pública e intelectual brasileiro: notas para compreensão
Authors: Dornelles Jonas Kunzler Moreira
Published: December 2019

O artigo visa apresentar aspectos da carreira intelectual do escritor, médico psicanalista, jornalista e político Dyonélio Machado. Partindo de sua trajetória biográfica, busca-se indicar suas principais contribuições para certas áreas do conhecimento. Destacado intelectual de seu tempo, ainda assim sua carreira acabou sofrendo devido a prisão política, ao boicote editorial, e quando eleito deputado, a cassação de mandato. O que fica evidente é a integridade do sujeito, que não admitia concessões, e que em todas áreas a que se dedicava, desenvolvia com seriedade seu trabalho intelectual. Com isso, busca-se contribuir para a respeitabilidade de sua figura, por vezes aviltada em sua trajetória.
De perseguidor a perseguido – de perseguido a perseguidor
Authors: Cerveira Mirian Rejane Flores , Cerveira Luis Alexandre
Published: December 2019

Este artigo tem a intenção de fazer uma apreciação reflexiva, sobre os paradigmas da teologia, mais especificamente sobre a abordagem no enfoque chamado pluralista ou “pluralismo das religiões”. Visa abordar o tema do diálogo inter-religioso. Diante de um Brasil tão plural e com muitas expressões religiosas alarga-se a necessidade de um tema tão relevante. Violência, intolerância e injustiça são características de muitos dos encontros entre diferentes religiões. Sua reflexão se realiza à luz da fé visto pelo pluralismo religioso, ou seja, a pluralidade das religiões, sobre o fato da existência de não apenas uma religião, mais de muitas tradições religiosas.
O vento sopra onde quer: pneumatologia e diversidade religiosa
Authors: Da Silva Wellington Cristiano
Published: December 2019

A presente pesquisa propõe-se estabelecer um caminho de diálogo do Cristianismo com as grandes religiões a partir da Pneumatologia. O ponto de partida é a Sagrada Escritura. O testemunho bíblico aponta para a ação universal do Espírito Santo. Ele age para além das fronterias do Cristianismo, pois “o vento sopra onde quer” (Jo 3,8). Em seguida, à luz do Concílio Vaticano II, parte-se para o diálogo da Igreja com as religiões promovido pela ação do Espírito Santo. Constata-se, por conseguinte, que o Espírito dá a todos a possibilidade de se associarem ao mistério pascal de Cristo por um modo só de Deus conhecido (GS 22). Vários documentos do Magistério da Igreja reforçarão esta possibilidade no Espírito. A Igreja igualmente reconhece que o Espírito Santo suscita nos corações das pessoas de diferentes povos e culturas uma diversidade de valores espirituais. Assim, o avanço na pesquisa pneumatológica garante uma justificação e fundamentação para o diálogo inter-religioso.
TERRITORIES OF ADVANCING DEVELOPMENT AS
INSTITUTIONAL MECHANISM OF INVESTMENT ACTIVITY RESTORATION
IN DEPRESSIVE REGIONS
Authors: Ilukhina I.B. , Ilminskaya S.A.
Published: December 2019

One of the overcoming mechanisms of regional development differentiation is creation of territories with preferential business mode. Since 2015 territories of advancing social and econom-ic development (TASED) have been organized in the Far East and in Siberia. The purpose of their creation is to increase business activity and development of non-primary production. In the work influence of TASED on the investment activity of the regions is analyzed and the conclusion is made about the efficiency of this institutional mechanism aimed at overcoming of spacial development disproportion.
АКТУАЛЬНЫЕ ПРОБЛЕМЫ ПОВЫШЕНИЯ СОБИРАЕМОСТИ НАЛОГОВ НА РЕГИОНАЛЬНОМ УРОВНЕ
Authors: Хасанова С.С. , Хатуева Р.Р. , Абдулазизова Э.А. , Исаева Э.М.
Published: December 2019

Статья посвящена проблеме повышения уровня собираемости налогов. Рассмотрены актуальные проблемы при администрировании по отдельным видам налогов и общие показатели по контрольной работе. Проведен сравнительный анализ за несколько лет для анализа относительно собираемости налогов.
PENERAPAN STRATEGI EXAMPLE NON EXAMPLE DENGAN BANTUAN MEDIA GAMBAR PADA MATERI PERISTIWA ALAM UNTUK MENINGKATAN HASIL BELAJAR SISWA KELAS V SEMESTER II SDN 4 PATOKAN TAHUN PELAJARAN 2018/2019
Authors: Yulianto Dodik Eko
Published: December 2019

Materi pelajaran yang disampaikan guru kepada siswa seharusnya senantiasa diingat agar siswa nantinya siap menghadapi ujian kenaikan kelas yang mau tidak mau akan mereka hadapi. Seorang guru harus mencari cara atau strategi untuk membangkitkan ingatan siswa terhadap segala materi yang sudah pernah diterimanya dalam proses pembelajaran. Pembelajaran adalah proses yang dapat mempengaruhi perubahan dari segi perilaku dan cara berfikir pada diri manusia yang dapat ditingkatkan. Strategi yang digunakan dalam penelitian ini adalah strategi Example Non Example. Example Non Example adalah strategi yang dapat digunakan untuk mengajarkan definisi konsep. Penelitian ini menggunakan Penelitian Tindakan Kelas sebanyak 2 siklus. Sasaran penelitian adalah siswa kelas V semester II di SD Negeri 4 Patokan Situbondo. Data yang diperoleh berupa hasil Tugas kelompok, tes formatif, lembar observasi kegiatan belajar mengajar. Hasil analisis menunjukkan bahwa siswa mengalami peningkatan hasil belajar dari siklus I menuju siklus II, yaitu masing-masing 71,43% dan 100%. Kesimpulan dari penelitian ini adalah strategi Example Non Example dengan bantuan media gambar dapat berpengaruh positif terhadap hasil belajar siswa mata pelajaran IPA materi peristiwa alam kelas V semester II di SD Negeri 4 Patokan Situbondo.
PENGARUH KESELAMATAN DAN KESEHATAN KERJA TERHADAP KINERJA KARYAWAN BENGKEL RANGKUTI MOTOR UKUI PELALAWAN
Authors: Lamin Lamin
Published: December 2019

ABSTRAKPENGARUH KESELAMATAN DAN KESEHATAN KERJA TERHADAP KINERJA KARYAWAN BENGKEL RANGKUTI MOTOR UKUI PELALAWAN Oleh: LAMIN, SE.MM Sekolah Tinggi Ilmu Ekonomi Riau (STIER) Jln. HR. Subrantas 57 Panam Pekanbaru 28293 Telp. (0761) 63237 E-mail: akbar_stier@yahoo.comPenelitian ini bertujuan untuk mengetahui keselamatan dan kesehatan  terhadap kinerja karyawan. Dalam penelitian ini data dikumpulkan melalui kuesioner terhadap 32 orang .Teknik analisis data yang digunakan adalah analisis regresi berganda,yang berfungsi untuk membuktikan hipotesis penelitian. Hasil pengujian 1 adalah  keselamatan berpengaruh signifikan terhadap kinerja karyawan dilihat dari t-hitung lebih besar dari t-tabel (4,414>2,042). Hasil pengujian 2 adalah  kesehatan berpengaruh signifikan terhadap kinerja karyawan dilihat dari t-hitung lebih besar dari t-tabel (2,363>2,042). Hasil pengujian 3 keselamatan dan kesehatan  berpengaruh signifikan terhadap  kinerja karyawan dilihat dari tingkat signifikansi 0,00 < 0,05. Dan hasil regresi linear berganda menunjukkan Y= a + bX1+bX2 yaitu: Y=-2,340+0,623X1+0,317X2. Dari persamaan regresi tersebut disimpulkan bahwa koefisien regresi dari bx bernilai Positif. Hal ini menunjukkan variabel bebas apabila ditingkatkan persamaanya akan menimbulkan kenaikan pada variabel terikatnya. hasil R Square sebesar 0,535 (53,50%) menerangkan bahwa kinerja karyawan bengkel Rangkuti Motor Ukui dipengaruhi oleh keselamatan dan kesehatan sebesar 53,50% .Kata Kunci: Keselamatan dan Kesehatan,  Kinerja Karyawan     ABSTRACTEFFECT OF SAFETY AND HEALTH OF WORK ON EMPLOYEE WORK PERFORMANCE OF RANGKUTI MOTORS OF UKUI PELALAWANBy: LAMIN, SE.MMRiau School of Economics (STIER)Jln. HR. Subrantas 57 Panam Pekanbaru 28293 Tel. (0761) 63237E-mail: akbar_stier@yahoo.comThis study aims to determine the safety and health of employee performance. In this study data were collected through a questionnaire of 32 people. The data analysis technique used was multiple regression analysis, which serves to prove the research hypothesis. The result of testing 1 is that safety has a significant effect on employee performance seen from the t-test greater than t-table (4,414> 2,042). Test result 2 is that health has a significant effect on employee performance seen from the t-test greater than t-table (2,363> 2,042). The results of testing 3 safety and health have a significant effect on employee performance seen from the significance level of 0.00 <0.05. And the results of multiple linear regression shows Y = a + bX1 + bX2, namely: Y = -2.340 + 0.623X1 + 0.317X2. From the regression equation it is concluded that the regression coefficient of bx is positive. This shows that the independent variable will increase if the dependent variable increases. R Square results of 0.535 (53.50%) explained that the performance of Rangkuti Motor Ukui workshop employees was influenced by safety and health by 53.50%.Keywords: Safety and Health, Employee Performance
Pengaruh Kualitas Produk Kerudung Rabbani terhadap Tingkat Kepuasan Konsumen Di Kota Bandung
Authors: Tiorida Ermina , Pramono Tangguh Dwi , Sifauziah Sifauziah
Published: December 2019

Bandung is the center of Muslim fashion in West Java even at the national level. This causes intense business competition in the world of Muslim fashion. To that end, an important role that must be performed by a company is to prioritize product quality and product innovation as a basis for attracting customer so that customer can feel satisfaction from the quality of the products produced. According to Google trends Rabbani trends also experienced a decline in customer interest in the purchasing Muslim fashion. And the results of distributing pre-research questionnaires obtained 70.45% or 31 people were disappointed with the quality of their muslim fashion, this resulted in customer not satisfied with the Rabbani. This study aims to determine how the quality and innovation of Rabbani products to customer satisfaction in the city of Bandung. According to Garvin (1987) there are eight dimensions to test product quality variables, namely performance, features, reliability, conformance, durability, serviceability, aesthetic and perceived quality. Customer satisfaction is measured by three dimensions, namely overall quality, customization and reliability. The study was conducted using quantitative methods. The sampling technique using non-probability sampling techniques and questionnaires were distributed to Rabbani customer in Bandung as many as 150 respondents. Analysis of research data using SEM PLS (Partial Square Structural Equation Modeling) with SmartPLS 3.0 software. the results showed that product quality and innovation had a significant effect on customer satisfaction
THE INFLUENCE OF PLAYING BALL TOWARD MOVEMENT ACTIVITY ABILITY TO HYPOACTIVE AUTISM CHILDREN
Authors: Imanniyah Anggawati
Published: December 2019

Hypoactive autism children were indicated by slow motoric activity so that it caused the children difficult to move. The children tended passive and they did not have any interest to do movement activity and preferred alone when they looked their friends playing. To help hypoactive autism children in enhancing movement activity ability it required a game which attracted the children’s interest to move i.e. through playing game.

The purpose of this research was to analyze movement activity ability before and after giving intervention using playing ball (passing and shooting), with time allocation 10 times meeting and 8 times intervention. This research used quantitative approach with the one group pretest posttest design. The subjects were 5 hypoactive autism children. For data analysis this research used statistic non parametric formula of sign test kind and the method of data collection applied observation and test.

From the research result which was then analyzed by using sign test formula, it was obtained that the value of Z counting 1,78 while the value of Z table with critic value 5% one side test was obtained 1,64 so that Z counting 1,78 was greater than Z table1,64 it meant that null hypothesis (Ho) was refused and work hypothesis (Ha) was accepted. In this way it could be concluded that playing ball influenced toward movement activity ability of hypoactive autism children
EFEKTIVITAS METODE DEMONSTRASI DALAM MENINGKATKAN TATA TERTIB BERWUDHU BAGI ANAK DENGAN HAMBATAN INTELEKTUAL
Authors: Despalantri Elda
Published: December 2019

Penelitian ini dilakukan pada seorang anak dengan hambatan intelektual yang ringan. Hasil pengamatan awal ditemui ada anak dalam melakukan wudhu belum sempurna, dan tidak berurutan. Maka dari itu peneliti ingin meningkatkan tata tertib berwudhu anak dengan hambatan intelektual sesuai tata tertib berwudhu melalui metode demonstrasi. Jenis penelitian yang digunakan adalah Single Subject Research dengan desain A – B. Ukuran target behaviornya dengan persentase. sedangkan data dianalisis menggunakan analisis visual grafik yang terdiri dari analisis dalam kondisi dan antar kondisi. Setelah data dianalisis, maka didapat persentase tata tertib berwudhu yang tertinggi pada kondisi baseline adalah 54,16 %. Sedangkan pada kondisi intervensi persentase tata tertib berwudhu yang didapat adalah 95,83 %, artinya bahwa kemampuan tata tertib berwudhu anak jauh lebih meningkat. Pada kondisi baseline tingkat level perubahan tata tertib berwudhu adalah 12,50 % (+) artinya menunjukkan ke arah positif bahwa persentase tata tertib berwudhu yang di dapat selama kondisi baseline sedikit naik namun persentasenya masih rendah. Sedangkan untuk intervensi tingkat level perubahannya adalah 29,83 % (+) artinya menunjukkan ke arah yang positif bahwa persentase tata tertib berwudhu yang didapat selama kondisi intervensi jauh meningkat dibandingkan dengan kondisi baseline. Sedangkan untuk persentase overlapenya didapat 0 %, artinya semakin kecil persentase overlape maka semakin baik pengaruh intervensi terhadap target behaviour. Dengan demikian hipotesis yang dikemukakan sebelumnya dapat diterima.
TYPICAL BEHAVIOUR OF JUVENILE DELINQUENCY IN SENIOR HIGH SCHOOL STUDENT
Authors: Syahadat Yustisi Maharani
Published: December 2019

This study aims to see how the typical behavior of juvenile delinquency is carried out by high school students. This research uses a qualitative approach. Taking participants in this study using purposive sampling techniques with the characteristics of participants is a teenage student in high school who lived separately from his parents since the beginning of high school with a research location in one private school. Researchers also use key person techniques, where researchers get complaints from several teachers from the school. The number of clients in this study was 1 person. Data collection techniques with semi-structured interviews, semi-participant observation and data analysis were performed using thematic analysis. This study revealed the typical symptoms/ behavior of juvenile delinquency displayed by the client. The negative behavior of these participants raises problems in the field of education and relationships with family and social environment.
PENGARUH METODE PEER EDUCATION TERHADAP INTRADIALYTIC WEIGHT GAIN (IDWG) PADA PASIEN HEMODIALISIS
Authors: Desnita Ria Desnita
Published: December 2019

Masalah umum pada pasien gagal ginjal tahap akhir yang menjalani terapi hemodialisis adalah ketidakpatuhan dalam pembatasan cairan. Intradialytic weight gain (IDWG) merupakan indikator kepatuhan dalam pembatasan cairan. Salah satu cara untuk meningkatkan kepatuhan pasien dalam pembatasan cairan adalah dengan metode peer education. Metode peer education merupakan metode edukasi dengan melibatkan pendidik sebaya sebagai pemberi edukasi pada kelompok pasien hemodialisis. Tujuan penelitian ini adalah untuk mengetahui pengaruh metode peer education terhadap IDWG pada pasien hemodialisis. Desain penelitian ini adalah quasi eksperimen dengan one group pretest and posttest design. Penelitian ini dilakukan di RST Dr. Reksodiwiryo Padang. Penelitian ini dilakukan pada bulan Januari – Agustus 2018. Jumlah sampel pada penelitian ini adalah 10 orang pasien hemodialisis. Hasil analisis data menggunakan paired t test menunjukkan ada pengaruh metode peer education terhadap intradialytic weight gain (IDWG) pada pasien hemodialisis (p= 0,000). Diharapkan pada perawat di unit hemodialisis memberikan edukasi kepada pasien dengan melibatkan pendidik sebaya sebagai pemberi edukasi.
HUBUNGAN KESEHATAN SPIRITUAL DENGAN KUALITAS HIDUP ORANG DENGAN HIV/AIDS DI YAYASAN LANTERA MINANGKABAU SUPPORT PADANG
Authors: Sastra Lenni
Published: December 2019

Angka kejadian HIV/AIDS terus mengalami peningkatan setiap tahunnya. Permasalahan yang dihadapi orang dengan HIV/AIDS sangat kompleks. Salah satu dampak dari permasalahan adalah penurunan kualitas hidup. Kualitas hidup seseorang dapat dipengaruhi oleh kesehatan spiritual. Tujuan penelitian ini adalah untuk mengetahui hubungan antara kesehatan spiritual dengan kualitas hidup orang dengan HIV/AIDS. Jenis penelitian adalah deskriptif analitik dengan pendekatan cross sectional study. Populasi pada penelitian ini adalah orang dengan HIV/AIDS di Yayasan Lantera Minangkabau Support Padang dengan jumlah sampel sebanyak 50 orang yang diambil dengan teknik total sampling. Data dianalisis secara univariat menggunakan uji chi square dengan tingkat kepercayaan (CI) 95 % dengan nilai α = 0,05. Hasil penelitian menunjukkan lebih dari separoh (64%) orang dengan HIV/AIDS memiliki kualitas hidup buruk, 36% memiliki kualitas hidup baik, lebih dari separoh (60%) memiliki kesehatan spiritual buruk dan 40% memiliki kesehatan spiritual baik. Hasil uji statistik di dapatkan ada hubungan kesehatan spiritual dengan kualitas hidup orang dengan HIV/AIDS di Yayasan Lantera Minangkabau Support Padang. Berdasarkan hasil penelitian ini dapat disimpulkan bahwa orang dengan HIV/AIDS dengan kesehatan spiritual buruk cenderung memiliki kualitas hidup buruk, sedangkan orang dengan HIV/AIDS dengan kesehatan spiritual baik memiliki kualitas hidup baik. Diharapkan kepada agar perawat untuk untuk meningkatkan kesehatan spiritual  orang dengan HIV/AIDS agar kualitas hidup mereka bisa lebih baik lagi.
Synthesis and characterization of bis(4-amino-2-bromo-6-methoxy)azobenzene derivatives
Authors: Martínez-López David , Babalhavaeji Amirhossein , Sampedro Diego , Woolley G Andrew
Published: December 2019

Aminoazobenzene derivatives with four ortho substituents with respect to the N–N double bond are a relatively unexplored class of azo compounds that show promise for use as photoswitches in biology. Tetra-ortho-methoxy-substituted aminoazobenzene compounds in particular can form azonium ions under physiological conditions and exhibit red-light photoswitching. Here, we report the synthesis and characterization of two bis(4-amino-2-bromo-6-methoxy)azobenzene derivatives. These compounds form red-light-absorbing azonium ions, but only under very acidic conditions (pH < 1). While the low pKa makes the azonium form unsuitable, the neutral versions of these compounds undergo trans-to-cis photoisomerization with blue-green light and exhibit slow (τ1/2 ≈ 10 min) thermal reversion and so may find applications under physiological conditions.
In Situ Raman Spectra of a Conical Conductive Shell as an Electro Galvanic Spin Orbit Transformer (SPOT)
Authors: Fontein Florian , Fischer Ulrich
Published: December 2019

Experimental results are interpreted, which were obtained by tip enhanced Raman Spectroscopy (TERS) in a specific SNOM (Scanning Near-Field Optical Microscope) STM (Scanning Tunneling Microscope) configuration with a tunnel gap. The interpretation is performed in terms of a classical physical model of a photon as a vacuum phonon polariton. The metal tip is considered as a conductive infinitely thin shell of a diamagnetic electron gas. The stationary single electron tunnel current of an electron tunnel passage frequency f

tunnel

  carries not the charge e but is shown to carry an energy hf

e
and an isotropic orbital angular momentum h/4π which corresponds to an isotropic transversal electron spin density of an angular frequency 2π

2

f

e
.Raman Spectroscopy, Electron Spin, Photon Spin, relativistic Quantum mechanicsThe electron spin current corresponds to an isotropic azimuthal inertial torque which acts on the photon by an increase of its energy and torque. Neglecting the influence of thermal and radiative losses of the conductive shell, the interpretation reproduces the spectroscopic results within the uncertainty of the experimental results. The photoelectric Raman spectrum of the tunnel gap can be regarded as a complex admittance spectrum which depends in a nonlinear way on the tunnel  voltage, the tunnel current and the wavelength of the scattered light. The conical tunnel gap configuration can be considered as a bipolar Electro-Galvanic Spin -Orbit Transformer (SPOT) and from a thermodynamic viewpoint as a Quantum Energy Converter
Evaluation of Anti-HBs Antibody Immune Response against Hepatitis B virus in Vaccinated People in а North-eastern Bulgaria Region
Authors: Tsaneva-Damyanova Denitsa T. , Ivanova Liliya I. , Pavlova Silviya N. , Todorova Svetlana B. , Popova Tsvetelina K.
Published: December 2019

Introduction: Hepatitis B virus (HBV) is one of the most significant human pathogens responsible for a huge number of acute and chronic liver infectious diseases worldwide.

Aim: To find the duration of post-vaccination immune response in individuals allocated to five age groups from 6 months to 20 years.

Materials and methods: All tested subjects were born between 1999 and 2018 and therefore covered by the compulsory vaccination program against hepatitis B. For the serological marker anti-HBs Ab we investigated 449 serum samples taken from ambulatory people and patients of St Marina University Hospital in Varna.

Results: A positive antibody response (anti-HBs Ab > 10 mIU/ml) was reported in 79.7% (n = 51) of the group of subjects up to one year old, in 70.0% (n = 196) of the subjects in the age range 1 year/1 month to 15 years, and in 39.3% (n = 33) of the subjects 15 years/1 month to 20 years old. Female sex had a better post-vaccination response than male sex with statistically significant relationship between sex and anti-HBs Ab titer (χ2 = 24.76, p <0.01).

Conclusions: Regardless of the mass immunization against HBV in Bulgaria, the relative share of chronic HBV infections does not show a downward trend. Therefore, it is very important to study the duration of the post-vaccination immune response by demonstrating the anti-HBs antibodies and to apply a booster dose from the vaccine if needed.
Effects of Chaenomeles maulei Fruit Juice on Reserpine-induced Behavioral Changes in Rats
Authors: Borisova Vesela A. , Eftimov Miroslav Tz. , Valcheva-Kuzmanova Stefka V.
Published: December 2019

Background: The fruit juice from Chaenomeles japonica var. maulei (Mast.) Lavall,e is very rich in polyphenolic compounds.

Aim: The aim of the current study was to investigate the effects of Chaenomeles maulei fruit juice (CMFJ) on reserpine-induced beha-vioral changes in rats.

Materials and methods: The experimental design included a total of 50 animals, divided in the following groups: control, R, R+CMFJ2.5, R+CMFJ5, and R+CMFJ10. All groups except the control received a single intraperitoneal injection of reserpine while the Control group was injected with the vehicle. CMFJ was applied through an orogastric cannula at 0, 19, and 23 hours after reserpine injection at doses of 2.5 ml/kg, 5 ml/kg, and 10 ml/kg to groups R+CMFJ2.5, R+CMFJ5, and R+CMFJ10, respectively. The groups control and R received distilled water (10 ml/kg) at the same time points. The open field test (OFT) and the forced swim test (FST) were carried out. In the OFT, crossings and rearings were recorded as a measure of locomotor activity. In the FST, the immobility time served as a measure of depressive-like behavior.

Results: In the OFT, the number of crossings of rats were significantly reduced (p<0.05) by reserpine. CMFJ antagonized the effects of reserpine on rat locomotor activity. In the FST, reserpine caused an insignificant reduction of the immobility time while CMFJ reversed this effect probably by increasing the locomotor activity.

Conclusion: CMFJ reversed reserpine-induced hypokinesia in rats. This effect of CMFJ might be attributed to the polyphenols found in very high concentrations in the juice.
Fatal Chemotherapy-induced Combined Infection in a Hodgkin’s Disease Patient: a Case Report
Authors: Kalchev Yordan I. , Lengerova Gergana B. , Asif Uswah , Burnusuzov Hasan A. , Murdjeva Marianna A.
Published: December 2019

Multimodal therapy, used for the treatment of patients with Hodgkin’s disease (HD), makes them prone to life-threatening infections, attributed mainly to febrile neutropenia. Herein, we present a case report of fatal combined bacterial and viral infection in a 49-year-old female patient, subject to polychemotherapy for HD. Rapid microbiological diagnosis performed by multiplex polymerase chain reaction elucidated the causes of the infection within hours. Listeria monocytogenes was detected in both the cerebrospinal fluid and blood samples. Nasopharyngeal swabs returned positive for two swine-derived strains of influenza A virus. We aimed to emphasize the importance of these pathogens and draw attention to their association in the aetiology of infections among patients receiving chemotherapy. In conclusion, better surveillance is needed to improve the early diagnosis of infectious complications in these patients.
Socio-demographic Factors Affecting Initiation and Duration of Breastfeeding in a Culturally Diverse Area of North Eastern Greece
Authors: Tsanidou Eirini , Gougoula Vasiliki , Tselebonis Athanasios , Kontogiorgis Christos , Constantinidis Theodoros C. , Nena Evangelia
Published: December 2019

Background: Breastfeeding is not only important for the bond between the mother and the child but is also associated with many health benefits. Socio-demographic factors have been found to be important for the initiation and longer duration of breastfeeding. 

Aim: To record the breastfeeding characteristics and to explore possible associations with socio-cultural and demographic factors in a culturally diverse area in Greece.

Materials and methods: A questionnaire including information about breastfeeding characteristics, medical history and demographics was completed by parents of children in the primary schools of the area.

Results: The study included 700 school-age children (352 boys), mean age 9.4±1.9 years. Breastfeeding was reported in 54.9% of them, with median (IQR) duration of 120 (range 60-360) days. Prevalence of breastfeeding was slightly higher in semi-urban areas, versus rural or urban settlements, but the duration there was significantly lower (p<0.001). Better educated mothers tended to initiate or sustain breastfeeding for a longer period; however, this difference was not statistically significant. Children of the native Muslim minority had been breastfed for a longer time (median duration 360 vs. 120 days, p<0.001), however, no difference was noted in prevalence.

Conclusion: Prevalence of breastfeeding in Greece is approximately 55%, similar to previous reports and along with duration is determined by certain socio-cultural factors.
Molecular-genetic Method for Fast Direct Detection of Staphylococcus Aureus and Methicillin Resistance in Blood Cultures and Punctures
Authors: Gergova Raina T. , Tsitou Virna-Maria S. , Mitov Ivan G.
Published: December 2019

Background: Invasive infections caused by methicillin resistant Staphylococcus aureus and coagulase-negative staphylococci (MRSA/MRSCoN) require fast, adequate treatment. 

The aim of this study was to develop a faster protocol for direct detection of MRSA/MRSCoN in blood cultures and in abscess punctures based on mecA and species specific identification of S. aureus by polymerase-chain reaction (PCR).

Materials and methods: We examined 77 growth-positive BACTEC blood cultures and 50 abscess punctures by routine microbiological assay and simultaneous PCR detection of MRSA/MRSCoN. The speciﬁcity of the PCR was evaluated by using DNA from another 15 microbial species for negative controls. We determined the minimum inhibitory concentration (MIC) of oxacillin, vancomycin, tigecycline, linezolid, levofloxacin, clindamycin, and erythromycin against the S. aureus isolates using the E-test. 

Results: In the blood cultures, the two methods detected 39.3% of MRSA, and 93.9% of MRCoNS. In the punctures, the PCR assay identified 20.9% of MRSA and 79.2% of MSSA. In the puncture cases, there were three PCR MRSA positive and culture negative samples. Screening for susceptibility to 14 antimicrobial agents demonstrated significantly higher (p<0.05) methicillin resistance in blood culture isolates than in the puncture ones (39.3% and 20.0%, respectively). 

Conclusion: The new PCR protocol was very fast and specific. It was more sensitive in detecting MRSA from abscess punctures than the routine microbiological techniques. This protocol will speed up the right choice of empirical therapy, which is extremely important for saving patients’ lives.
Intradural Extramedullary Metastasis of the Upper Thoracic Spine – Case Report and Literature Review
Authors: Kehayov Ivo , Genova Sylvia , Gicheva Maria , Nuri Bahar , Kitov Borislav
Published: December 2019

We report a case of 46-year-old male operated on for moderately differentiated lung adenocarcinoma. Postoperatively, he underwent six courses of chemotherapy and radiotherapy. He developed progressive severe inferior paraparesis accompanied by excruciating pain between the shoulders two years later. Magnetic resonance imaging revealed metastases in the bodies of T2 and T3 vertebrae with adjacent intradural extramedullary lesion compressing the spinal cord. The patient underwent surgical decompression and vertebral body cement augmentation that lead to pain relief and partial neurological recovery. The histological examination was consistent with metastases from low differentiated pulmonary adenocarcinoma. Surgical resection of intradural extramedullary metastasis improves patient quality of life by reducing pain intensity and neurological deficit.
Evaluating the Effectiveness of Simulation Training in Obstetrics and Gynecology, Pediatrics and Emergency Medicine
Authors: Sandeva Milena G. , Tufkova Stoilka , Ketev Kostadin , Paskaleva Diana
Published: December 2019

Simulation training in medicine is a powerful tool for acquiring knowledge and practical skills in an environment close to the real world. Decreasing training opportunities directly on the patient tend to introduce simulations close to the real hospital environment without compromising the patient’s safety. 

The aim of the study was to evaluate the effectiveness of simulation training in the Medical Simulation Training Center (MSTC) at the Medical University of Plovdiv.

A prospective observational descriptive study was performed at the MSTC at Plovdiv Medical University between September 2017 and March 2019. The study included 245 respondents who participated in one or more practical simulation trainings and were surveyed.

The results of the study suggest that the knowledge, skills and attitudes of the trainees improve after training sessions. By increasing the number of visits, the self-esteem and confidence in performing the manipulation also increases, knowledge and technical performance significantly improve and mistakes are reduced. A statistically significant relationship has been demonstrated between the sequence of visits and acquired competencies (p=0.0001). There are no performance mistakes in those attending three or more times, but 16.2% of them still experience uncertainty while performing. Here, however, 83.8% performed the manipulation automatically and without mistakes. 

Simulation training in medicine is effective and useful. It has its place in the curriculum for students and is a good tool for acquiring knowledge, skills and techniques in postgraduate education.
Study of the effect of selective inhibitor of Arginase II KUD 975 and of low doses of Acetylsalicylic acid on the functional parameters of the cardiovascular system In experimental preeclampsia
Authors: Severinova Olga V. , Gureev Vladimir V. , Zhilinkova Lyudmila A. , Lazareva Galina A. , Gureeva Anastasia V. , Lazareva Sofia S.
Published: December 2019

Introduction: Over the past decade, preeclampsia has been the subject of an increased attention, as this complication is the most common cause of maternal mortality, triggering every third case of obstetric morbidity and taking lives of up to 50.000 young women worldwide each year. Despite a large number of ongoing studies, no clear algorithm for monitoring pregnant women with this pathology has been developed yet.

Materials and methods: The study was conducted on 220 female Wistar rats weighing 250–300 g. In the experiment, ADMA-like preeclampsia model was used.

Results and discussion: The introduction of L-NAME to the animals from the 14th till the 20th day of pregnancy causes the following disturbances: a rise in systolic and diastolic blood pressure in 1.4 and 1.5 times, an increase in proteinuria in 3.3 times and an increase in the content of fluid in the greater omentum from 44.39 ± 1.62% to 55.02 ± 1.74%, all of which correspond to the disorders in pregnant women in case of preeclampsia. The use of the selective inhibitor of arginase II KUD 975 (3mg/kg/day) in combination with acetylsalicylic acid (10mg/ kg/day) leads to a pronounced correction in the emerging changes: a decrease in systolic and diastolic blood pressure in 1.2 and 1.3 times, a decrease in proteinuria in 1.9 times and a decrease in the fluid content in the greater omentum.

Conclusion: Selective inhibitor of arginase II KUD 975 and small doses of acetylsalicylic acid have a pronounced positive effect in the correction of morphofunctional disorders in animals with ADMA-like preeclampsia.
Bone as a Cement Restrictor in Elbow Arthroplasty
Authors: Sharma S , Rymaszewski L A
Published: December 2019

Bone chips harvested from the distal end of the humerus are effective as a cement restrictor in elbow arthroplasty.
The Joint Reduction Method of Revision Total Knee Arthroplasty
Authors: Masini Michael A , Kester Mark A
Published: December 2019

The joint reduction method of revision total knee arthroplasty uses a single instrument that serves as both a trial and cutting guide, allowing surgeons to test the knee by performing a joint reduction before making any resections on the distal femur.
Michael B. Millis on Periacetabular Osteotomy
Authors: Millis Michael B
Published: December 2019

The Bernese acetabular osteotomy was pioneered by Reinhold Ganz, MD, of Bern, Switzerland, and is sometimes called the Ganz osteotomy. Michael B. Millis, MD, one of the most experienced surgeons in the United States with this technique, provides an update for Orthopedics.
Does Graded Reaming Affect the Composition of Reaming Products in Intramedullary Nailing of Long Bones?
Authors: Kouzelis Antonis Th , Kourea Helen , Megas Panagiotis , Panagiotopoulos Elias , Marangos Markos , Lambiris Elias
Published: December 2019

abstract

Reaming products taken during intramedullary nailing were examined to identify possible differences in their composition depending on the reaming percentage. Reaming products were taken from 39 fresh closed tibial and femoral diaphyseal fractures in patients with an average age of 29 years. According to histology, reaming products mainly consisted of bone trabecular viable or nonviable, and bone marrow stroma. A statistically significant reverse correlation exists between viable bone mass percentage and reaming progress. Reaming 1 mm less than the minimum canal diameter provides a higher viable bone mass percentage, which might be an important factor in the bone healing process.
Management of First-Time Patellar Dislocations
Authors: Geary Michael , Schepsis Anthony
Published: December 2019

Palellotemoral instability represents a continuum of abnormal patellofemoral joint mechanics, ranging from infrequent subluxation to recurrent dislocation.
Multiple Fractures of the Axis
Authors: Korres Demetrios S , Papagelopoulos Panayiotis J , Mavrogenis Andreas F , Sapkas Georges S , Patsinevelos Antonios , Kyriazopoulos Petros , Evangelopoulos Demetrios
Published: December 2019

abstract

Multiple fractures of the axis are not common lesions. A retrospective study was performed to identify the different fracture patterns and to analyze the incidence of these injuries and their long-term behavior. The medical records of 674 consecutive patients with fractures of the cervical spine were reviewed.

Nine (1%) of 674 patients (6 men and 3 women) had multiple fractures of the axis. Mean patient age was 48 years. The most common lesion was a combination of traumatic spondylolisthesis with either an odontoid process or a teardrop fracture of the axis body. All patients were treated conservatively with an excellent or good outcome at mean 12-year follow-up (range: 2-18 years). Computed tomography was the imaging modality of choice for the correct diagnosis of these rare lesions.
Comparison of Intramedullary Nailing of Distal Third Tibial Shaft Fractures: Before and After Traumatologists
Authors: Obremskey William T , Medina Miguel
Published: December 2019

abstract

We hypothesized that less malalignment and complications occur with intramedullary nailing of distal third tibia fractures (42A, B, C) after the implementation of orthopedic trauma surgeons to this level II community hospital. We also hypothesized that patients with ≥5° of malalignment have poorer function as measured by the MODEMS functional outcome scale. Two cohorts of distal third tibia fractures were identified by discharge diagnosis or by the Orthopaedic Trauma Association database. Group I (n=39) patients were stabilized with an intramedullary nail by community orthopedic surgeons. Group II (n=18) patients were treated by orthopedic trauma surgeons. In Group I (community), 9 (23%) patients treated by the community surgeons exhibited >5° of angulation in at least one direction. Five (13%) of these patients displayed angulation in more than one direction, and 3 of these patients exhibited >10° of angulation. In Group II (trauma) 1 (5%) patient had >5° angulation in any plane (P<.05). No differences were noted in time to union, nonunion, delayed union, hardware failure or infections between the two groups. Functional outcomes were assessed using the MODEMS lower limb module. In comparison of the patients with and without significant anguiation, the P value for bodily pain was 0.042. Patients treated by the community orthopedic surgeons had a higher incidence of malalignment, as compared to those treated by orthopedic trauma specialists.
Swelling Behavior and Drug Release of Polymer Coated Nano Iron Oxide Embedded Hydroxyapatite
Authors: Yokogawa Yoshiyuki , Ohkura Rina , Inoue Yoko , Shishido Atsumasa , Ansar Ereath Beeran , Varma Hari Khrisna
Published: December 2019

Spherical calcium-alginate gel beads containing HAIO, iron oxide (IO) nanoparticles embedded on hydroxapatite (HA), were prepared along with and poly (N-isopropylacrylamide) (PNIPAAM) or chitosan. These spheres, HAIO, HAIO-PNIPAAM and HAIO-chitosan spheres, were used as carriers of 5-fluorouracil (5-FU), one of the drugs for cancer chemical therapy, and the 5-FU release behavior in PBS solution was investigated at ambient and elevated temperatures using U-V spectrometry. The amount of the released 5-FU from the HAIO spheres was somewhat higher than that from HAIO-PNIPAAM and HAIO-chitosan spheres at ambient temperature. At elevated temperature, HAIO spheres showed an increase in quantity of released 5-FU. The amount of released 5-FU from HAIO-PNIPAAM spheres was almost the same, and that from HAIO-chitosan spheres was reduced compared to those at ambient temperature. These spheres, HAIO, HAIO-PNIPAAM and HAIO-chitosan spheres, show the similar swelling properties at elevated temperature. However, the combinations of Ca-alginate - PNIPAAM or Ca-alginate - chitosan may produce the different structures, which are core-shell network for HAIO-PNIPAAM spheres and or a polyelectrolyte complex for HAIO-chitosan spheres, leading to a different release behavior of 5-FU.
Effect of Apatite Nuclei on Apatite-Forming Ability of Cellulose Nanofiber
Authors: Yoshioka Takuya , Yabutsuka Takeshi , Takai Shigeomi , Yao Takeshi
Published: December 2019

Cellulose nanofiber-apatite nuclei composites were fabricated by mixing apatite nuclei with cellulose nanofiber slurry and air-drying. Then apatite-forming ability could be imparted to cellulose nanofiber-apatite nuclei composites. In order to investigate significance of mixed apatite nuclei, cellulose nanofiber-hydroxyapatite composites were fabricated by mixing commercially obtained stoichiometric hydroxyapatite particles with cellulose nanofiber slurry, and the bioactivity was evaluated by using simulated body fluid.
Development of Bioactive Apatite Nuclei-Precipitated Ti-12Ta-9Nb-6Zr-3V-O Alloy
Authors: Yabutsuka Takeshi , Kidokoro Yasutaka , Takai Shigeomi , Yao Takeshi
Published: December 2019

Ti-12Ta-9Nb-6Zr-3V-O alloy, one of the shape-memory alloys with lower Young’s modulus in comparison with conventional titanium alloy, was treated with sulfuric acid to form roughened surface on the substrate. In order to impart hydroxyapatite formation ability to the Ti-12Ta-9Nb-6Zr-3V-O alloy, apatite nuclei (AN) were precipitated on the roughened surface using simulated body fluid (SBF) adjusted at higher pH than physiological condition. By this treatment, AN-precipitated Ti-12Ta-9Nb-6Zr-3V-O alloy was obtained. The AN-precipitated Ti-12Ta-9Nb-6Zr-3V-O alloy showed high hydroxyapatite formation ability in physiological SBF.
Fixed Orthodontic Treatment in a Child Patient with Dentoalveolar Fracture: A Case Report
Authors: Yohana Winny
Published: December 2019

The incidence of dentoalveolar fracture in children is high about 18% because they are often active, lack of body coordination, and immature mental. The dentoalveolar fractures treatment to the children differs from adults, because of the immature bone structure. The purpose of this study is to investigate the treatment of dentoalveolar fracture in child patient using fixed orthodontic appliance. A 15-year-old boy treated with braces caused by malocclusion class 1 Angle type 1. The child suffers from dentoalveolar fracture of the mandibular anterior tooth and mandibular alveolar bone injury after a motorcycle accident. Fortunately, the patient was using an orthodontic fixed appliance that served as a splinting so that severe damage could be prevented. Treatment: the wound was cleaned by betadine antiseptic solution, and braces bonding on the labial of anterior teeth. The lingual region was splinted with wire as 0.7 SS combined with composite resin to make splinting stronger. The patient was given 500mg amoxicillin and 500mg ibuprofen. Wire SS 0.016 is indicated to have superior strength, and the strength remains a support in fixed orthodontic therapy because the stainless steel alloys are of "18-8" austenitic type contain chromium (7-25%), Nickel (8-25% ) and Carbon (1-2%). Chromium in this stainless steel alloy customs a thin oxide layer which blocks the diffusion of oxygen into the alloy and allows the corrosion resistance of the alloy. Stainless steel is introduced for the use of creating appliances. Archwires have high stiffness, low springiness, corrosion resistance, low range and good formability. These wires are often less expensive than the other ones and they can be readily used as archwires in an orthodontic treatment and splinting as well. After two months of splinting treatment, the tooth position approximately back to normal; there was unification alveolar bone in the radiographic evaluation. Dentoalveolar fracture treatment is to restore the teeth and alveolar bone in order that dentoalveolar structure to function properly, and aesthetic function is achieved.