bluuebunny/crossref_metadata_2025 huggingface dataset:
STUDY ON THE LEVEL OF KNOWLEDGE ABOUT MEDICAL MARIJUANA AMONG MEDICAL STUDENTS
Authors: Bielski Arkadiusz , Hus Aleksandra , Sadowska Anna , Kosson Dariusz
Published: October 2020

Introduction: Medical marijuana is used in many diseases. There are not many studies on society’s knowledge about use of medical cannabis. This study aimed to check the level of knowledge about aspects of medical cannabis among students of medical and medical emergency degree courses. Authors emphasize the need of knowledge about law regulations, composition, properties or contraindications of medical cannabis among students of medical universities, as they are fundamental resource of information for patients and any other person who is not included in medical world.
Material and methods: An original questionnaire containing 29 questions was created. There were 311 randomly selected students from medicine (N=52), nursing (N=117), midwifery (N=66), paramedicine (N=54) and dietetics (N=22). Results of the study were evaluated with help of statistical test ANOVA and student t-test. The Bioethical Committee at the Medical University of Warsaw took note of the information about the study and issued a statement with reference number AKBE/35/2020.
Results: The correctness of answers among students was on the average level of 24.06%. In the survey, the highest percentage of correct answers was characteristic for medical students, achieving about 35.0% effectiveness, then medical emergency students answered correctly in 26.9%, nursing – 23.7%, obstetrics – 21.5%, dietetics – 13.2%. Among all groups, the answer was “I don’t know”: medical students – 44.0% of all answers, emergency medical services – 53.2%, nursing – 56.2% obstetrics – 62.4%, dietetics – 73.9%. The value of correct answers was assessed as statically valid in the ANOVA test; at the significance level p = 0.05 (F-ratio: 11.32004; p = 0.0001). In the t-student test,it was proved that the ANOVA test result relates to the variance of responses between all study groups except dietetics.
Conclusions: The level of knowledge of medical students is insufficient to inform patients about possibility of using medical marijuana in their diseases. The low level of knowledge is conditioned by little time at the university devoted to medical marijuana. Education of students about medical marijuana should be increased.
THE HERBAL MEDICINE CONTAINING OF IVY LEAF DRY EXTRACT IN THE TREATMENT OF PRODUCTIVE COUGH IN CHILDREN
Authors: Olszanecka-Glinianowicz Magdalena , Doniec Zbigniew , Schönknecht Karina , Almgren-Rachtan Agnieszka
Published: October 2020

The aim: The assessment of the therapeutic effects of the herbal medicine containing of ivy leaf dry extract administered twice a day in children with productive cough and their guardians’ satisfaction with the use of this syrup.
Material and methods: A multicenter, observational survey was conducted by 268 doctors working in Primary Health Care. The survey was conducted during two routine, consecutive outpatient visits (including first supplemented retrospectively) resulting from the needs of therapy.
Results: The study group consisted of 5162 patients treated for productive cough with the herbal medicine containing of ivy leaf dry extract administered twice a day. In 75.7%, productive cough was intense, in 61.6% it occurred at night, in 49.8% it was very common (several times per hour), and in 62.7% it affected daily activity. Most often the syrup containing of ivy leaf dry extract was used in doses twice a day for 2 ml or 4 ml. During observation the percentage of children with intensive, very common, night and affected daily activities cough decreased significantly. Very satisfied with a therapeutic effect of the preparation containing of ivy leaf dry extract administered twice a day were 68.2% of children guardians.
Conclusions: The use of the herbal medicine containing of ivy leaf dry extract administered twice a day may be a good alternative to current therapeutic regimens in the treatment of productive cough in children. This recommendation is supported by effectiveness comparable to other medicines and a high level of satisfaction with its use by patients and guardians of chidren.
NEUROPHYSIOLOGICAL FEATURES OF THE NOCICEPTIVE TRIGEMINAL PATHWAY IN ABDOMINALLY OBESE MIGRAINEURS
Authors: Nikiforova Olena S. , Delva Mykhaylo Yu.
Published: October 2020

The aim of this study were to assess clinical (cutaneous allodynia) and neurophysiological (R2 nBR component) markers of the nociceptive trigeminal-cervical pathway sensitization in the abdominally obese patients with episodic (EM) and chronic migraine (CM).
Materials and methods: It had been recorded nBR within interictal period in 79 migraineurs with EM and CM who had abdominal obesity (AO) and normal body weight (NBW).
Results: Patients with EM and AO had significantly lower pain thresholds than patients with EM and NBW – 0,55 (0,34-0,63) μV vs 0,70 (0,59-1,03) μV. The mean latency of R2 nBR component was significantly decreased in patients who had EM and AO (36,59 (31,95-42,41) ms) compared to patients who had EM and NBW(46,75 (42,93-52,34) ms). It had been revealed significant increasing of the mean amplitude of the component R2 nBR in patients who had EM and AO (158 (115-197) μV) compared to patients who had EM and NBW (124 (76-144) μV). In patients who had CM and AO, it had been found direct positive correlation between the amplitude of R2 nBR and severity of cutaneous allodynia – τ=0,4 (p=0,03), as well as found negative correlation between the latency of R2 nBR and severity of cutaneous allodynia – τ=-0,44 (p=0,02) within the interictal period of migraine.
Conclusions: Neurophysiological findings may indirectly indicate faster migraine chronification in patients with EM and AO.
RESEARCH OF RHEOLOGICAL PROPERTIES OF MEDICINAL SYRUP FOR ORAL USE
Authors: Davtian Lena L. , Kukhtenko Galyna P. , Voronkina Alona S. , Kudria Viktoria V.
Published: October 2020

The aim of the present research was to investigate the rheological properties of the medicinal syrup for oral administration with glucosamine hydrochloride and levocarnitine. Matherials and methods: Coefficient of the dynamic flow (at shear rates of 3,49 and 10,3 s -1, as well as at shear rates of 27.2 and 149.0 s-1), mechanical stability, the index of destruction and restoration were studied. The rheological (structural-mechanical) properties of the samples were determined using a Rheolab QC rotary viscometer (AntonPaar, Austria) with coaxial cylinders CC27 / S-SN29766. The rheological parameters were studied at the temperature 20±0,5 °С.
Results: It is established that the syrup has weakly expressed plastic viscous and thixotropic properties (the hysteresis area for the syrupis 1710.19 Pas/s). Such results characterize the system as a reopex.
Conclusions: The results of the study enables classification of the research object as system with a low degree of fluidity. Such dependence is typical for systems of the Newtonian type of flow and characterizes the syrup under investigation as a weakly structured disperse system.
MATHEMATICAL MODELING OF THE STRESS-STRAIN STATE OF THE “BONE-IMPLANT” SYSTEM DURING THE OSTEOSYNTHESIS WITH A PHILOS WITH POLYLACTIC ACID IMPLANTS
Authors: Korzh Mykola O. , Makarov Vasyl B. , Lipovsky Volodymyr I. , Morozenko Dmytro V. , Danylchenko Svitlana I.
Published: October 2020

The aim: To study was to use mathematical modeling in assessing the stress-strain state of the bone-implant system during plate osteosynthesis with a PHILOS plate of a proximal humerus fracture with polylactic acid implants.
Materials and methods: Two bone-implant systems with a three-fragment humerus fracture according to the Neer classification (type 11-C1 according to the AO / ASIF classification) were selected for the study, one of which was with additional reinforcement of the head fragment with two polylactic acid implants (PLA – polylactide Ingeo™ Biopolymer 4032D). Sawbones (Europe AB, Malmö, Sweden) built the humeral model on 3D scanning of the composite model № 3404 of the left humerus.
Results: A comparative analysis of the obtained results of mathematical modeling of the stress-strain state of the bone-implant systems showed that with given constraints (hand abduction to 90°), the use of two polylactic acid implants can reduce the stress in the plate and screws, respectively, by 11% and 6% .
Conclusions: The use of polylactic acid implants during osteosynthesis of three- and four-fragment fractures of the proximal humerus, especially in the case of osteoporosis, allows providing for the reinforcement of metal structures and supporting of the articular surface without deterioration of fixation rigidity.
DETERMINATION OF THE STRUCTURE OF ACUTE INJURY OF TEMPORARY AND PERMANENT FRONTAL TEETH IN CHILDREN, ANALYSIS OF DIAGNOSTIC AND TREATMENT MEASURES AND THEIR EFFECTS
Authors: Trufanova Valentina P. , Sheshukova Olha V. , Lyakhova Natalia A. , Polishchuk Tetiana V. , Bauman Sofia S. , Stavytskyi Stanislav O.
Published: October 2020

The aim: To determine the structure of acute injuries of temporary and permanent frontal teeth in children, to analyze the applied diagnostic and treatment measures for acute tooth trauma and to investigate their effectiveness.
Materials and methods: The subject of the study were 31 children aged 2-12 years with acute temporary and permanent tooth trauma. Methods: clinical (radiological, thermodiagnosis), medical and statistical.
Results: The number of injured permanent teeth was greater than the number of injured temporary teeth. The pattern of temporary and permanent tooth injuries differed, so in temporary teeth dislocations were observed, and in permanent teeth fractures prevailed over dislocations. In our opinion, this is due to the peculiarities of the anatomy of the temporary teeth. Usually, the therapeutic tactics of acute temporary teeth injuries is to remove them, despite their important role in the growth and development of jaws, physiological formation and eruption of permanent teeth. The therapeutic tactics of dynamic observation in the case of intrusive dislocation of the temporary tooth were selected in the clinic of the Department of Pediatric Dentistry. In some cases, with a slight change in the position of the temporary tooth, self-regulation of its position was observed, in other cases the tooth remained dystopic, but its viability remained in 50% of cases.
Therapeutic tactics of acute injuries of permanent teeth were selected according to the type of trauma. In the case of permanent tooth dislocation, with a slight change in its position, tooth immobilization was carried out by splinting with fiberglass tape and photopolymer composite material.
Conclusions: Our observations have shown that the complex of modern specialized medical care for the affected children with acute traumatic injuries of the teeth should be guided by their preservation, which ensures the subsequent normal formation of the dental-jaw apparatus. To ensure these conditions, a long, reliable immobilization of the damaged tooth is required as soon as possible after injury.
MODELING THE TELESCOPIC CONNECTION DEVICE OF RAINBOW MUSCLE PROTESES
Authors: Tarashevska Yuliia Ye.
Published: October 2020

The aim: Mathematical modeling and peculiarities of the proposed telescopic connection design.
Materials and methods: For the implementation of the mathematical model of telescopic joints of removable dentures, elements of the external and internal parts of such a design having the same nominal angles of cones, or identical nominal cones of these parts are considered.
Results: Dependence of retention force is determined from various parameters, equating it with equilibrium values of compressive dynamic force and the total force of friction. Connection is set between the separate geometricalparameters of elements of telescopic cone connection andoperating between them various internal and external efforts.At creation of different individual modifications of theseconnections, gives possibility, attracting the values ofcorresponding geometrical or power elements, that isrationed or accepted on results measuring or scanouts, toexpect other parameters that is determined in dependenceon preliminary appointed.
Conclusions: The given mathematical dependences can be represented as algorithms of calculation and realized by computer programs.
MRI AND ULTRASOUND CRITERIA FOR THE DIAGNOSIS OF A SPORTS HERNIA IN FOOTBALL PLAYERS
Authors: Ioffe Oleksandr Yu. , Negria Natalia M. , Omelchenko Anastasiia V. , Stetsenko Oleksandr P. , Dibrova Yuri A. , Kryvopustov Mykola S. , Tsiura Yuri P. , Tarasiuk Tatiana V.
Published: October 2020

The aim of the study is to specify diagnostic MRI and ultrasound criteria for a sports hernia in order to verify its diagnosis in football players.
Materials and methods: The study included 50 professional and amateur football players aged 15 to 34 from 2016 to 2019. The criteria for inclusion in the study were: the presence of groin pain in football players, which prevented them from continuing to actively participate in sports activities.
Results: The findings of the study revealed that during MRI the two factors, which had the strongest influence, were “increased MR signal intensity on PDfs observed from the structures of the inguinal canal” and “increased MR signal intensity on PDfs observed from bone marrow of superior ramus of the pubic bone”. During ultrasound of the inguinal area, the main criterion for a sports hernia diagnosis was “increased size of the inguinal canal”. The verification of the diagnosis was carried out on the basis of the presence of a protrusion in the posterior wall of the inguinal canal. For a sports hernia diagnosis the MRI sensitivity is 91.67% (95% CI 77.5 – 98.2), specificity –78.57% (95% CI 49.2 – 95.3) and the sensitivity of ultrasound is 88.89% (95% CI 73.9 – 96.9), the specificity – 50% (95% CI 23.0 – 77).
Conclusions: The combination of MRI and ultrasound makes it possible to accurately detect the presence of a sports hernia in the football player. Based on the findings of our study, we formulated MRI and ultrasound criteria for a sports hernia diagnosis.
DEVIATIONS OF PATIENTS WITH DRUG ADDICTION VALUE AND MEANING SPHERE FUNCTIONING
Authors: Filts Oleksandr O. , Sedych Kira V. , Lavrinenko Vitalii A. , Mychailiv Svitlana V.
Published: October 2020

The aim of this article is to study empirically drug addicts value-meaning sphere disorders.
Materials and methods: To study the drug addicts value-meaning sphere disorders indicators, Schwarz’s «Value Questionnaire» and a structured interview of the respondents, aimed at studying the specifics of their meaning constructs, was used.
Results: Meaning structure disorders are analyzed on the basis of the constructs and images of fixed imagination, which are used by drug addicts to describe the role of the addictive agent in their life, description. The system of myths of drug addicts, which reflects their attempts to constructively justify changes in their life and behavior in the use of psychoactive substances and shows the existence of compensatory mechanisms in the psyche of drug addicts, is analyzed.
Conclusions: Value-meaning sphere functioning disorders play a significant role in the process of drug addiction formation, which is realized through the alteration of the value system, the presence of value conflict, the influence of images of fixed imagination and myths on the attitude to drug addiction.
OPTIMIZATION OF PATHOGENETIC THERAPY IN PATIENTS WITH CHRONIC OBSTRUCTIVE LUNG DISEASE
Authors: Potyazhenko Mаksym M. , Ishcheikin Kostiantyn Ye. , Nastroga Tetiana V. , Sokolyuk Nina L. , Kitura Oksana Ye. , Gorodnytska Inesa M.
Published: October 2020

The aim of the study is to increase the effectiveness of the treatment of exacerbation of COPD group B GOLD II with the use of combined therapy of the combined drug PulmoBRIZ containing two components – ambroxol and acetylcysteine and the course of halotherapy.
Materials and methods: We observed 60 patients with COPD B, GOLD II. They were divided into two groups: the first – the main (n=30) – patients receiving basic therapy, mucolytic therapy – a combination of Ambroxol and acetylcysteine – 200/30 to 1 tabl. 2 times a day, number 7 days and, from the 3rd day – sessions of halotherapy 1 time per day № 10. The second group, the control group (n=30), followed only basic therapy, did not take mucolytics and halotherapy sessions.
Results: Patients receiving therapy with the combination of ambroxol and acetylcysteine and halotherapy sessions experienced a significant increase in FEV1 by 8.3% (p <0.05); the Tiffon index was 7.2% (p<0.05), reactive anxiety levels (RA) and manifestations of autonomic dysfunction decreased, whereas in patients in the control group these indicators did not improve significantly.
Conclusions: The proposed complex therapy of COPD patients with the inclusion of the combined drug ambroxol and acetylcysteine and halotherapy sessions contributes to the improvement of the quality of life of patients.
EFFECT OF ULTRASOUND ON S. EPIDERMIDIS MUSEUM CULTURE
Authors: Sidash Yuliia V. , Boychenko Olha N. , Popovych Ivan Yu. , Zaytsev Andrii V.
Published: October 2020

The aim of the present research project was to study the effect of ultrasonic waves on the S. epidermidis ATCC 14990 museum culture.
Materials and methods: A bibliosemantic method – for analyzing previous research based on scientific literature, electronic resources, empirical methods of scientific research (observation, comparison, measurement, experiment) – to study the effect of ultrasound on the strain of S. epidermidis ATCC 14990.
Results: A study showed that when exposed to ultrasound for four and a half minutes on a culture of microorganisms S. epidermidis in glass tubes, the number of viable cells in the suspension decreases.
Conclusions: The influence of ultrasound on the culture of S. epidermidis, studied in the work, showed that the selected and used parameters of ultrasound treatment cause destructive changes in microorganisms. These changes are not fatal for the entire bacterial culture used in the study, but they have a reliable antimicrobial effect.
STATUTORY OBLIGATIONS OF A DOCTOR IN THE FIELD OF PREVENTION AND CONTROL OF INFECTIOUS DISEASES
Authors: Paszkowska Małgorzata
Published: October 2020

The spread of infectious diseases has been and poses a serious threat to the health of the entire population. The world is currently struggling with a SARS-CoV-2 coronavirus infection pandemic. The problem also concerns Poland and results in new legal regulations being issued. The law defines instruments for preventing and combating infectious diseases and infections. Every doctor has legal obligations related to infectious diseases. They are determined primarily by the Act of 5 December 2008 on preventing and combating infections and infectious diseases in humans. The purpose of the article is to present legal norms regarding the physician’s duties in the field of preventing and combating infectious diseases. In addition, doctors closer knowledge of new legal regulations related to the SARS-coronavirus CoV-2.The analysis shows that doctors play an important role in implementing legal instruments for the prevention of infectious diseases. Various forms of medical coercion may be used to prevent infectious diseases.
SPECIFICS AND DIAGNOSTIC PROCEDURE IN REFLUX-RELATED DYSPHONIA
Authors: Sowa Klaudia , Łobaczuk-Sitnik Anna , Piszczatowski Bartosz , Duchnowska Emilia , Kosztyła-Hojna Bożena , Nadolny Klaudiusz , Ładny Jerzy Robert , Zdrojkowski Maciej
Published: October 2020

Voice is a work tool for many professional groups. Currently, cases of dysphonia of multiple origin consist a growing issue. Voice disorders may result from disturbed voice production process, congenital defects, post-traumatic conditions, chronic diseases or hormonal disorders. Chronic diseases causing voice disorders include laryngopharyngeal reflux disease and esophageal reflux disease. The chronic character of reflux causes the formation of numerous morphological changes of the larynx, including: hyperemia of the mucosa limited to arytenoid and intraarytenoid area, edema of the vocal folds, edema of the larynx mucosa. These changes contribute to voice disorders. Among the pathological changes of voice organ etiologically associated with reflux, the following disease units may be distinguished: reflux laryngitis, subglottic edema, contact ulceration, larynx granuloma, larynx and pharynx cancer. Many of disorders in the upper respiratory tract are etiologically related to reflux, e.g. dysphonia, grunting, coughing and dyspnoea.
ORBITAL PSEUDOTUMOR − CURRENT STATE OF KNOWLEDGE
Authors: Gacan Marceli , Papuć Ewa , Rejdak Konrad
Published: October 2020

The orbital pseudo-tumor is an orbital inflammatory disease of unknown origin that can affect all the anatomical structures that make up the orbit. The diagnosis is based on the assessment of clinical symptoms, imaging tests and the exclusion of other possible causes. Glucocorticosteroids are used for treatment, but other immunosuppressants as well as biological treatments can be used.
The aim of the study is to present, based on the literature review, the current state of knowledge about pathogenesis, symptoms, differential diagnosis, and treatment of the orbital pseudotumor.
COURSE OF A SARS-CoV-2 PNEUMONIA IN A MIDDLE-AGED MALE PATIENT
Authors: Harsch Igor Alexander , Skiba Marcin , Heß Thomas , Wedel Frank , Lopatta Eric , Konturek Peter Christopher
Published: October 2020

The SARS-CoV-2 infection has recently been declared a pandemic by the WHO. Most fatalities occur in elderly people with comorbidities. However, SARS-CoV-2 pneumonias do also occur in younger patients with no comorbidities or risk factors at all. We report here on one of the “early” cases that occurred in Germany. A 57-year-old man was infected and developed pneumonia after a skiing vacation in Northern Italy. Other members of the travel group also fell ill, but only showed flu-like symptoms. Only a few if any infections originated from the affected person; at this point in time the infection situation in the region could still be grasped. Under supportive measures, the disease developed positively despite impressive radiological findings. The positive course is likely also due to the age of the person affected and the lack of any risk factors. The case does also exemplify thata good health condition does not necessarily protect from acquiring a moderately severe SARS-CoV-2 infection.
HETEROTOPIC PREGNANCY – CASE REPORT
Authors: Swiniarski Michal , Sadkowska Monika , Roman Grzegorz , Szeszko Lukasz , Sipak-Szmigiel Olimpia
Published: October 2020

Heterotopic pregnancy is the simultaneous occurrence of intrauterine and ectopic pregnancy. This situation is very rare (1:30 000 pregnancies), while recently, with the development of assisted reproductive techniques, the incidence has increased to 1:100 – 1:500 pregnancies.
The aim of the study is to present the situation of coexistence of intrauterine pregnancy and ruptured tubal pregnancy. The case concerns a 32-year-old patient in the 12th week of the second pregnancy in whom the only risk factor was the state after Caesarean section and thus possible intraperitoneal adhesions. The ultrasound revealed normal intrauterine pregnancy and a very large amount of free fluid in the smaller pelvis. After immediate surgical intervention, a ruptured right tubal pregnancy was found. Right fallopian tube was removed. After the operation, the patient with the preserved intrauterine pregnancy was discharged from the ward. Further intrauterine pregnancy was normal. Delivery by Caesarean section.
Conclusions: The described case indicates that the existence of intrauterine pregnancy does not exclude the existence of ectopic pregnancy and emphasizes the great importance of correctly and accurately carried out ultrasound examination in the first trimester of pregnancy along with appendicitis assessment. Early diagnosis of heterotopic pregnancy reduces the risk of complications.
A FIRST CLINICAL CASE REPORT OF WEST NILE VIRAL ENCEPHALITIS IN POLTAVA REGION OF UKRAINE
Authors: Kotelevska Tеtiana M. , Pryimenko Nataliia O. , Dubynska Halyna M. , Iziumska Olena M. , Koval Tеtiana I , Pikul Kateryna V. , Purdenko Tеtiana Y.
Published: October 2020

West Nile Fever (WNF) is the most common arbovirus infection caused by West Nile Virus (WNV), which has been responsible for numerous epidemic outbreaks of disease among humans, birds and horses on all continents, with the exception of Antarctica, over the past two decades. On the territory of Ukraine, the earliest reports of cases of WNV circulation in humans and birds relate to the 70s of the XX century. In Poltava region WNF was first registered in 2011. Though the epidemiological and clinical patterns of WNF in Ukraine and Poltava region remain understudied, primarily due to the lack of alertness of practitioners to the problem of WNF and to broader access to laboratory diagnosis of the disease. The first clinical case of West Nile Viral encephalitis, registered on the territory of Poltava region, has been given and analyzed.
EXTRAPERITONEOSCOPIC RADICAL PROSTATECTOMY AFTER
PELVIC SUGERY PROCEDURES
Authors: Serniak Yuriy P. , Sagalevych Andriy I. , Frolov Oleksandr S. , Serniak Petr Y. , Kryvopustov Mykola S.
Published: October 2020

The aim of study is to evaluate the results of extraperitoneoscopic radical prostatectomy performed in the presence of various complicating factors.
Materials and methods: This prospective study included 7 patients with a diagnosis of prostate cancer (T1-T2b, No, Mo) who underwent extraperitoneoscopic radical
prostatectomy (ERPE).
Results: Among all ERPEs performed on seven patients, the maximum duration of the surgery was 6 hours 30 minutes, and the minimum one was 3 hours 40 minutes. The
average volume of blood loss did not exceed 350±20 ml; decline in hemoglobin level was in the range of 10-12 g/l. The urethral catheter was removed no earlier than 7 days after
the surgery. Drainage from the space of Retzius was removed on the 3rd day. Postoperative complications occurred in 2 patients (28.57%). The maximum period of postoperative
outpatient follow-up was 22 months. In 6 patients (85.71%), complete urinary retention up to 3 months was noted. One patient (14.29%) had mild urinary incontinence (PADtest
– no more than one pad per day). In these cases, sexual potency was absent in 100% of patients. The maximum postoperative PSA level in the group reached 0.13 ng/ ml.
Conclusions: Own experience of ERPE in patients on the background of previous transurethral resections and vaporization of the prostate demonstrated the effectiveness and
safety of the method. More extensive studies with a larger number of cases are needed.
COMPLEX ESTIMATION OF FITNESS TRAINING SYSTEMS AND
WOMEN’S SOMATIC HEALTH OF THE FIRST PERIOD MATURE AGE
Authors: Kornosenko Oksana К. , Taranenko Iryna V. , Zaitseva Yuliia V. , Petryshyn Oleksandr V.
Published: October 2020

The aim: To model, to ground and to check experimentally the efficiency of the complex organized system of fitness trainings and system of health improving trainings; to
discover their influence on the status of women’s somatic health of the first period mature age.
Materials and methods: Analysis, systematization, pedagogical observation, modelling, pedagogical experiment, tests: Ruffier, Stange, Romberg’s, Harvard step test and
tests of PWC170.
Results: Complex organized system of fitness trainings (dosed, systematic, complex motive activity, managed by trainer) appeared more effective (11.68 %) in comparison
with system of individual health improving trainings (6.54 %). Both systems contributed to reducing of weight (CG2 – 3.8 %, EG2 – 16.3 %),decrease in body’s parts sizes, in
particular, of breast (CG2 – 0.5 %, EG2 – 1.3 %), waist (CG2 – 2.3 %; EG2 – 13.75 %), pelvis (CG2 – 3.6 %; EG2 – 5.3 %), formation of physical characteristics (strength – CG2 – 2.1
%, EG2 – 17.4 % and flexibility – CG2 – 4.5 % and EG2 – 9 %).Differences in the level of physical capacity are marked, mainly, in the control group (PWC170absolute – 12.2 %;
PWC170relative – 19.3 %), in comparison with experimental (PWC170 absolute – 10.2 %; PWC170 relative – 17.5 %).
Conclusions: In general both systems assisted the improvement of somatic health level that proves the efficiency of system approach to organization of trainings in this agerelated
group.
USING OF ENDOVASCULAR CATHETER METHODS IN SURGICAL
TREATMENT PATIENTS WITH LUNG BLEEDING
Authors: Ponomarova Kateryna V. , Minukhin Dmytry V. , O.Yevtushenko Denis , Tokarev Andrey V. , Kudrevych Oleksandr M. , Hroma Vasiliy G.
Published: October 2020

The aim: Improve the results of the treatment of patients with pulmonary bleeding.
Materials and methods: We examined 57patients with lung bleeding different etiology, who were hospitalized in the department of Thoraco-Abdominal Surgery. All patients
were divided into two groups – of the main group 27patients and the comparison group 30 patients, depend of ages, sex, nosological form, level of lung bleeding. Patients aged
from 27 to 78 years, including 34 men (62,5%) and 23 women (37,5%.). The test diseases includes: bronchiectasis disease – in 21 (37,1 %), pulmonary fibrosis with malformation
BA – in 14 (24,7 %), abscess of the lung – in 9 (15,9 %), polycystic lung disease – in 6 (12,7 %), chronic obstructive pulmonary disease – in 5 (9,6 %).
Results: As a result of complete physical examination of patients with LB, it has been established that hemorrhage was the result of obstructive bronchitis in 14 patients (42%),
there was chronic obstructive pulmonary disease in 7 (21%) and bronchiectasis was diagnosed in 6 (18%) patients. In 2 (6%) patients pulmonary hemorrhage was caused by
community-acquired pneumonia. Central lung cancer was detected in 4 (12%) patients.
Conclusions: Bronchial artery angiography gives high efficiency in solving the problem of hemostasis in oncological and nonspecific lung diseases. Endovascular occlusion of
bronchial arteries permits: to elaborate diagnosis because of the presence of specific angiographic signs of malignant tumor; to perform effective endovascular hemostasis.
MODEL OF MANAGEMENT BY THE QUALITY OF LIFE OF OBESE
CHILDREN
Authors: Pomohaibo Kateryna H. , Martynenko Nataliya M. , Usenko Svitlana H.
Published: October 2020

The aim of the work is medical and social substantiation and development the model of management by the quality of life of obese children.
Materials and methods: Material processing was performed by using of mathematic-statistical methods: variance, correlation and regression analysis, mathematical prediction,
modelling; the relative, average values and their errors were calculated as well as the predictive coefficients, and the odds ratios, which made it possible to obtain reliable data.
Results: It was found that the real prevalence of obesity among children and adolescents in Kharkiv was significantly different from the official statistics in Kharkiv region (15,0
per 1,000 of infant population). The general level of excess weight in 2016 was 151,0±5,2‰.
It was developed a technique for predicting the risk of excess body weight in children based on a heterogeneous sequential recognition procedure, which with 95% of probability
can determine the patient’s belonging to a particular risk group.
Conclusions: The model of management by the quality of life for obese children was developed. Offered model of management allows to eliminate the managed factors of
development of this pathology, to conduct comprehensive monitoring of the state of children’s health, to eliminate certain shortcomings of the health care organization, in
particular at the primary level, to raise the awareness of the population on methods of prevention, to apply innovative medical technologies, which in turn will help to improve
the quality of life for obese children.
MOTIVATION AS ONE OF THE CONSTITUENT COMPONENTS OF
THE MODEL OF THE SYSTEM OF MEDICAL AND PSYCHOLOGICAL
SUPPORT FOR THE PROCESS OF ADAPTATION OF MEDICAL
COLLEGE STUDENTS TO WORK IN PRIMARY POSITIONS
Authors: Gryshnjaeva Olena V. , Меlnychenko Oleksandr A. , Yeryomenko Galyna V. , Grigoruk Victoria V. , Antsupova Vita V. , Vanina Yana A.
Published: October 2020

The aim: Based on previous studies, develop medical and psychological recommendations to increase the motivation for the work of nurses and medical assistants.
Materials and methods: During 2015–2018 Students of the Kharkov Regional Medical College (100 experimental people and 100 control groups) studied the types of motivation
of medical personnel to work in key positions. The article analyzes the relationship between motivation and the individual – typological characteristics of the person using the
psychodiagnostic methodology of the individually – typological questionnaire L.N. Sobchik and author’s profile A.V. Grishnyaeva.
Results: Аfter analyzing the above data, we can say that a combination of motivation or its absence with certain individual and typological characteristics of individuals leads
to different results of adaptation to the primary positions of future medical workers. The imbalance of individual-personality structures and motivation leads to an accentuation
of character, which contributes to maladaptation and professional burnout.
Conditions: Given the connection between motivation and individual – typological characteristics of the personality, it is possible to make the correct personnel distribution
and prevent the professional burnout of employees.
PREVALENCE OF POSTPARTUM ENDOMETRITIS AND ANTIMICROBIAL RESISTANCE OF RESPONSIBLE PATHOGENS IN UKRAINE: RESULTS A MULTICENTER STUDY (2015-2017)
Authors: Salmanov Aidyn G. , Vitiuk Alla D. , Zhelezov Dmytro , Bilokon Olga , Kornatska Alla G. , Dyndar Olena A. , Trokhymovych Olha V. , Bozhko Nataliia , Raksha Iryna I. , Nykoniuk Tetiana R. , Gorbunova Olga V. , Kokhanov Igor V. , Kushnirenko Stella , Iarotska Iryna , Golianovsky Oleg V. , Holovanova Iryna A. , Abbasova Esmira R.
Published: October 2020

The aim: To obtain the prevalence of postpartum endometritis women and antimicrobial resistance of responsible pathogens in Ukraine.
Materials and methods: We performed a retrospective multicenter cohort study. The study population consisted of all women who had a vaginal delivery or cesarean section
in 14 Regional Women’s Hospitals of Ukraine.
Results: Total 2460 of 25,344 patients were found to have postpartum endometritis, for an overall infection rate of 9.7%. The postpartum endometritis rates were 7.6% after
vaginal delivery and 16.4% after cesarean section. Incidence of postpartum endometritis after cesarean section is affected mainly by the mode of delivery (scheduled caesarean
deliveries (done before labor starts) – 13.8% and unscheduled caesarean deliveries (done after labor starts) – 22.5%. The predominant pathogens were: Escherichia coli (32.7%),
Enterococcus faecalis (13.0%), Streptococcus spp. (12.1%), Klebsiella spp. (10.4%) and Enterobacter spp. (10%). Among the antimicrobial agents tested, the ertapenem, piperacillin/
tazobactam, and cefotaxim were the most consistently active in vitro against Enterobacteriaceae in both vaginal deliveries and after cesarean section infections. The overall
proportion of extended spectrum beta-lactamase (ESBL) production among Enterobacteriaceae was 22.8% and of methicillin-resistance in Staphylococcus aureus (MRSA) 15.4%.
Conclusions: Postpartum endometritis and antimicrobial resistance of responsible pathogens presents a significant burden to the hospital system. Postpartum infections
surveillance is required in all women’s hospitals. This knowledge is essential to develop targeted strategies to reduce the incidence of postpartum infections.
MOTOR ACTIVITY AS THE BASIS OF A HEALTHY LIFESTYLE OF STUDENT YOUTH
Authors: Griban Grygoriy P. , Yavorska Tetiana Ye. , Tkachenko Pavlo P. , Kuvaldina Olga V. , Dikhtiarenko Zoia M. , Yeromenko Eduard A. , Lytvynenko Andrii M. , Hresa Nataliia V. , Okhrimenko Ivan M. , Ovcharuk Igor S. , Prontenko Kostiantyn V.
Published: October 2020

The aim is to find out the role of motor activity in developing a healthy lifestyle of student youth in the process of physical education.
Materials and methods: The study involved 647 students, aged 18-22. The research methods are the analysis and synthesis of the literature, analysis of curricula, programs,
methodological support and quality of training, questionnaires, and the methods of mathematical statistics.
Results: It is determined that the majority of the students had no need for a healthy lifestyle, the lack of knowledge in this area, low activity while performing the requirements
of a healthy lifestyle, irrational organization of educational activities, bad habits and other factors that negatively affect their health.
Сonclusions: The current system of physical education in the higher education institutions of Ukraine cannot change the attitude of students to a healthy lifestyle. The purpose
of physical education, in addition to the formation of physical skills and development of students’ physical qualities, should be educational work aimed at forming a positive
attitude towards a healthy lifestyle.
DO H. PYLORI STATUS AND SMALL INTESTINAL BACTERIAL OVERGROWTH DETERMINE THE CLINICAL COURSE OF CHRONIC ACTIVE GASTRITIS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS?
Authors: Radionova Tetiana O. , Skrypnyk Igor M. , Maslova Ganna S.
Published: October 2020

The aim: To define clinical peculiarities of chronic active gastritis in patients with type 2 diabetes mellitus (T2DM) considering Helicobacter pylori (HP) status and small intestinal
bacterial overgrowth (SIBO).
Materials and methods: 172 patients with chronic active gastritis were enrolled in the study, 92 out of them had concomitant T2DM. Symptoms were collected with the
questionnaire, HP infection was diagnosed with stool antigen test, SIBO was assessed with glucose hydrogen breath test.
Results: 87.5% (n=70) patients with chronic gastritis without DM had epigastric pain, however those with T2DM reported pain only in 41.3% (n=38) cases. Other symptoms
included: nausea, bloating, early satiety, postprandial fullness, heartburn, belching and vomiting. HP infection in patients with chronic gastritis and concomitant T2DM
is significantly associated with symptoms of epigastric pain (OR=2.78, 95%CI 0.92-8.41), bloating (OR=3.92, 95%CI 1.40-10.99), nausea (OR=2.32, 95%CI 0.85-0.6.30),
postprandial fullness (OR=1.45, 95%CI 0.54-3.87) and belching (OR=1.01, 95%CI 0.32-3.16), whereas SIBO – with bloating (OR=8.82, 95%CI 2.88-27.01), nausea (OR=5.15,
95%CI 1.88-14.10) and belching (OR=2.53, 95%CI 0.67-9.52).
Conclusions: Patients with T2DM and chronic active gastritis report epigastric pain significantly less than non-diabetics. HP infection probably plays a prominent role in
development of epigastric pain in patients with T2DM. Additionally, HP is linked to SIBO, which may lead to bloating, belching and nausea onset.
EFFECT OF ENOS GENE POLYMORPHISM ON THE COURSE OF EARLY ONSET BACTERIAL INFECTIONS IN PREMATURE INFANTS
Authors: Cherniavska Yuliia I. , Pokhylko Valeriy I. , Znamenska Tetiana K. , Vorobiova Olga V. , Hasiuk Nataliia I.
Published: October 2020

The aim of the study was to analyze the associations between 4a/4b polymorphism of the eNOS gene and impaired systemic hemodynamics in premature infants with early
neonatal sepsis.
Materials and methods: We conducted a prospective cohort study, which included 120 premature babies with early neonatal sepsis, in 57 children the course of the disease was
accompanied by arterial hypotension (AH) and in 61 children – not. In children of both groups, genotyping was performed to determine 4a/4b polymorphism of the eNOS gene.
Results: It was shown that the heart rate, blood pressure, hourly diuresis, the level of total nitrates and nitrites in the urine, as well as a number of echocardioscopic and
dopplerometric indicators in children with different eNOS gene genotypes are not different.
Conclusions: There is no effect of 4a/4b polymorphism of the eNOS gene on the occurrence of hemodynamic disturbances in premature infants with sepsis.
CURRENT STRATEGY FOR TREATMENT OF COMORBID STATES: COMPLICATED COMMUNITY-ACQUIRED PNEUMONIA WITH ARTERIAL HYPERTENSION
Authors: Burya Liliia V. , Vakhnenko Andrii V. , Moiseieva Nataliia V. , Kapustianska Anna A. , Zviagolska Iryna M.
Published: October 2020

The aim: To optimize the treatment of CAP patients with hypertension, complicated by exudative pleuritis.
Materials and methods: The study included 43 CAP patients, aged 46 to 65 years, with viral lesions along with hypertension. The average age of the patients was 52.5 ±
4.5 years. Verification of the CAP diagnosis and its formulation was performed in accordance with the order of the Ministry of Health of Ukraine No. 128 of 19.03.2007 “On the
approval of clinical protocols of medical care in “Pulmonology” in all patients, pneumonia was complicated by exudative pleuritis, which was confirmed by X-ray examination.
Results: The use of combination drugs, namely, torasemide with prolonged effect and tivortin aspartate in the treatment of patients with community-acquired pneumonia,
complicated by exudative pleuritis, combined with hypertension led to more significant positive changes in the values of saturation, blood biochemical parameters, as well as
accelerated recovery of patients, which was confirmed by the positive dynamics of X-ray examination.
Conclusions: As a result of the treatment, all parameters of the quality of life of the patients were greatly improved, which resulted in a significant reduction in functional
limitations and high social activity of the patients, which significantly reduced the cost of treatment.
DYNAMICS OF THE NUMBER OF PERSONS WITH SPECIAL NEEDS LIVING IN ZAKARPATTIA OBLAST, UKRAINE
Authors: Myronyuk Ivan S. , Slabkiy Gennadiy O. , Kabatsiy Nataliya O. , Levko Lesya V.
Published: October 2020

The aim: To study and analyze indicators of the number of persons with special needs living in Transcarpathian region of Ukraine: disabled persons, orphans and children
deprived of parental care.
Materials and methods: National statistical reports on the disability of the population, the number of orphans and children deprived of parental care for the period 2010-
2019. Statistical method was applied in the course of study.
Results: Analysis of the dynamics of the number of persons with special needs in Transcarpathian region for the period 2010-2019 showed an increase of the number of disabled
persons by 27% with 75415 persons, 6826 disabled children, 2125 orphans and children deprived of parental care. The number of orphans and children deprived of parental
care residing in the region have a tendency to reduce and in the year 2019 equals to 2125 orphans and children deprived of parental care.This requires improving of the system
of social and medical care for persons with special needs for adults with the formation of a system of provision of services in accordance with the actual needs of the population
with the maximum approximation of the service to the place of residence of the client with the maximum use of opportunities of the united territorial communities.
Conclusions: The growth of the number of persons with special needs in Transcarpathian region and directly of the persons with disabilities with the tendency to reduce the
number of orphans and children deprived of parental care is established.
HEART REMODELING, TREATMENT OF MYOCARDIAL INFARCTION WITH DIABETES MELLITUS 2ND TYPE AND HEART FAILURE
Authors: Potyazhenko Maxim M. , Lyulka Nadia O. , Ostapchuk Yulia A.
Published: October 2020

Scientific 42 articles were analyzed, which for analysis were taken from scientometric databases: Web of Science, Scopus, PubMed, Medline, on topics related to: heart remodeling,
treatment of myocardial infarction with type 2 diabetes mellitus and heart failure. Analysis of current medical studies and the data obtained indicate both availability in the
usage of new HF biological markers – suppressor of tumorigenesis 2 (ST2), and the efficiency in the use of antagonists of miniralocorticoid receptors and sodium-glucose
linked transporter-2 inhibitors, which is complicated by HF and type 2 diabetes by slowing down the processes of LV myocardial remodeling, which promotes control of blood
pressure and fluid volume and causes a decrease and gradual regression of HF regardless of its origin.
METHODS OF SPECTRAL DIAGNOSTICS IN MODERN PREVENTION
OF ONCOLOGICAL DISEASES
Authors: Adamczyk Jakub , Sieroń Dominik , Sieroń Karolina , Sieroń Aleksander , Kucharska Ewa
Published: October 2020

This paper contains structured information on photodynamic diagnostics. Photodynamic diagnostics is a young diagnostic modality used in the detection of pre-neoplastic and
very early neoplastic lesions. A characteristic feature of the presented method is its completely non-invasive nature and thus the possibility of multiple repetitions at the same
patient. This is very important in modern health care and in preventive measures.
Aim of the paper: The article aims to present technical and diagnostic possibilities of a photodynamic method as one of the possible modalities of screening diagnostics in
patients with ambiguous clinical picture of early neoplastic lesions.
PROGNOSTIC INDICES OF PATHOLOGICAL TOOTH WEAR DEVELOPMENT
Authors: Pavlenko Svetlana A. , Pavlenkova Elena V. , Tkachenko Irina. M. , Sidorova Alla I. , Korol Dmytro M.
Published: October 2020

The aim: To study possibilities of prognosis of pathological wear of tooth hard tissues development depending on the functional activity of masticatory muscles. Materials and methods: In order to achieve the goal of the study, a survey of patients at the age of 19 to 69 years was conducted for precision of number of persons who have increased tooth wear. During the examination of all patients, three groups were selected: control and two researched ones. Patients in the control group (30 patients between the age of 18 and 60 years old) had an intact dentition without any visible sign of increased tooth wear. The researched groups included 25 patients aged from 18 to 60 years old. The second research group included patients who had increased tooth wear of I-III level. The children of the patients of the II group with or without any sign of increased tooth wear were referred to the third research group. Results: The method of electromyography was performed for the study of peculiarities of the muscular activity of the maxillofacial area of the patients of the control and research groups. In our opinion, all manifestations of increased tooth wear are related to changes in the muscle system, the motor apparatus and the nervous activity of an organism. Conclusions: The study of direct muscular apparatus and related bone system may predict the possibility of developing of an increased tooth wear of young patients in the future and prevent its development, as well as to justify the application of a prevention and treatment plan of the studied pathology.