bluuebunny/crossref_metadata_2025 huggingface dataset:
Chemo-Diversity and Antiradical Potential of Twelve Matricaria chamomilla L. Populations from Iran: Proof of Ecological Effects
Authors: Piri Elahe , Mahmoodi Sourestani Mohammad , Khaleghi Esmaeil , Mottaghipisheh Javad , Zomborszki Zoltán Péter , Hohmann Judit , Csupor Dezső
Published: April 2019

Matricaria chamomilla L. is a popular medicinal herb that is used for healing various diseases and is widely distributed worldwide in temperate climate zones, and even in the subtropical climate of Southern and Western Iran. This study was aimed at comparing the volatile oil constituents, along with antiradical potential and HPLC analysis of methanolic extracts from twelve plant samples growing in Iran. The present research was carried out for the first time on these populations. Among seventeen identified volatile chemicals evaluated by GC/MS and GC/FID, representing 92.73–97.71% of the total oils, α-bisabolone oxide A (45.64–65.41%) was the major constituent, except in case of “Sarableh” as a new chemotype, where (E)- and (Z)-γ-bisabolene (42.76 and 40.08%, respectively) were the predominant components. Oxygenated sesquiterpenes (53.31–74.52%) were the most abundant compounds in the samples excluding “Sarableh” with 91.3% sesquiterpene hydrocarbons. “Sarableh” also exerted the most potent antioxidant capacity with EC50 = 7.76 ± 0.3 µg/mL and 6.51 ± 0.63 mmol TE (Trolox® equivalents)/g. In addition, populations “Lali” and “Bagh Malek” contained the highest amounts of apigenin and luteolin with 1.19 ± 0.01 mg/g and 2.20 ± 0.0 mg/g of plant material, respectively. Our findings depict a clear correlation between phytochemical profiles and antiradical potential of M. chamomilla and geographical factors.
Unsymmetrical Diboron Reagents: Application in Borylation Reactions of Unsaturated Bonds
Authors: Ding Siyi , Xu Liang , Miao Zongcheng
Published: April 2019

In the past decades, borylation reactions have received extensive research interest and have developed into effective tools in the synthesis of versatile organoboron compounds. Boranes and symmetrical diboron compounds are commonly utilized as borylating reagents in these transformations, especially in the borylation reactions of unsaturated bonds. More recently, several types of unsymmetrical diboron reagents have been synthesized and applied in these borylation reactions, allowing for complementary chemo- and regioselectivity. This review aimed to highlight the recent development in this rising research field, focusing on new reactivity and selectivity that originates from the use of these unsymmetrical diboron reagents.
Interaction of Dihydrocitrinone with Native and Chemically Modified Cyclodextrins
Authors: Faisal Zelma , Kunsági-Máté Sándor , Lemli Beáta , Szente Lajos , Bergmann Dominik , Humpf Hans-Ulrich , Poór Miklós
Published: April 2019

Citrinin (CIT) is a nephrotoxic mycotoxin produced by Aspergillus, Penicillium, and Monascus genera. It appears as a contaminant in grains, fruits, and spices. After oral exposure to CIT, its major urinary metabolite, dihydrocitrinone (DHC) is formed, which can be detected in human urine and blood samples. Cyclodextrins (CDs) are ring-shaped molecules built up from glucose units. CDs can form host-guest type complexes with several compounds, including mycotoxins. In this study, the complex formation of DHC with native and chemically modified beta- and gamma-cyclodextrins was tested at a wide pH range, employing steady-state fluorescence spectroscopic and modeling studies. The weakly acidic environment favors the formation of DHC-CD complexes. Among the CDs tested, the quaternary-ammonium-γ-cyclodextrin (QAGCD) formed the most stable complexes with DHC. However, the quaternary-ammonium-β-cyclodextrin (QABCD) induced the strongest enhancement in the fluorescence signal of DHC. Our results show that some of the chemically modified CDs are able to form stable complexes with DHC (logK = 3.2–3.4) and the complex formation can produce even a 20-fold increase in the fluorescence signal of DHC. Considering the above-listed observations, CD technology may be a promising tool to increase the sensitivity of the fluorescence detection of DHC.
A Quantitative Tandem Mass Spectrometry and Scaled-Down QuEChERS Approach for Simultaneous Analysis of Pesticide Multiresidues in Human Urine
Authors: Shin Yongho , Lee Jiho , Park Eunyoung , Lee Junghak , Lee Hye , Kim Jeong-Han
Published: April 2019

Multiresidual pesticide determination in a biological sample is essential for an immediate decision and response related to various pesticide intoxications. A rapid and simultaneous analytical method for 260 pesticides in human urine was developed and validated using liquid chromatography-tandem mass spectrometry (LC-MS/MS). High speed positive/negative switching electrospray ionization (ESI) mode was used, and scheduled multiple reaction monitoring (MRM) was optimized. Three versions of scaled-down QuEChERS procedures were evaluated, and the procedure using non-buffer reagents (magnesium sulfate and sodium chloride) and excluding cleanup steps was selected for optimum pesticide extraction. The limit of quantitation (LOQ) in this methodology was 10 ng/mL for each target pesticide, and correlation coefficient (r2) values of calibration curves were ≥0.988 (linearity range; 10–250 ng/mL). In accuracy and precision tests, the relative error ranges were −18.4% to 19.5%, with relative standard deviation (RSD) 2.1%–19.9% at an LOQ level (10 ng/mL), and −14.7% to 14.9% (RSD; 0.6%–14.9%) at higher concentrations (50, 150, and 250 ng/mL). Recovery range was 54.2%–113.9% (RSD; 0.3%–20.0%), and the soft matrix effect (range; −20% to 20%) was observed in 75.4% of target pesticides. The established bioanalytical methods are sufficient for application to biomonitoring in agricultural exposures and applicable in the forensic and clinic.
Quality Evaluation of Wild and Cultivated Schisandrae Chinensis Fructus Based on Simultaneous Determination of Multiple Bioactive Constituents Combined with Multivariate Statistical Analysis
Authors: Chen Shuyu , Shi Jingjing , Zou Lisi , Liu Xunhong , Tang Renmao , Ma Jimei , Wang Chengcheng , Tan Mengxia , Chen Jiali
Published: April 2019

Schisandrae Chinensis Fructus, also called wuweizi in China, was a widely used folk medicine in China, Korea, and Russia. Due to the limited natural resources and huge demand of wuweizi, people tend to cultivate wuweizi to protect this species. However, the quality of wild and cultivated herbs of the same species may change. Little attention has been paid to comparing wild and cultivated wuweizi based on simultaneous determination of its active components, such as lignans and organic acids. An analytical method based on UFLC-QTRAP-MS/MS was used for the simultaneous determination of 15 components, including 11 lignans (schisandrin, gomisin D, gomisin J, schisandrol B, angeloylgomisin H, schizantherin B, schisanhenol, deoxyschizandrin, γ-schisandrin, schizandrin C, and schisantherin) and 4 organic acids (quinic acid, d(−)-tartaric acid, l-(−)-malic acid, and protocatechuic acid) in wuweizi under different ecological environments. Principal components analysis (PCA), partial least squares discrimination analysis (PLS-DA), independent sample t-test, and gray relational analysis (GRA) have been applied to classify and evaluate samples from different ecological environments according to the content of 15 components. The results showed that the differential compounds (i.e., quinic acid, l-(−)-malic acid, protocatechuic acid, schisandrol B) were significantly related to the classification of wild and cultivated wuweizi. GRA results demonstrated that the quality of cultivated wuweizi was not as good as wild wuweizi. The protocol not just provided a new method for the comprehensive evaluation and quality control of wild and cultivated wuweizi, but paved the way to differentiate them at the chemistry level.
Improving Upconversion Efficiency Based on Cross-Patterned Upconversion Material Slot Waveguides on a Silicon Layer
Authors: Kim Youngsoo , Moon Kihwan , Lee Young Jin , Hong Seokhyeon , Kwon Soon-Hong
Published: April 2019

Upconversion (UC) materials can be used to harvest near-infrared (NIR) light and convert it into visible light. Although this improves optical device operating spectral range and efficiency, e.g., solar cells, typical UC material conversion efficiency is too low for practical devices. We propose a cross-patterned slot waveguide constructed from UC material embedded in a high index semiconductor layer to improve UC. Since the slot waveguide mode is induced in the low index UC slot, NIR absorption (~970 nm) increased 25-fold compared with film structures. Furthermore, the spontaneous emission enhancement rate at 660 nm increased 9.6-fold compared to the reference film due to resonance excited in the UC slot (Purcell effect). Thus, the proposed UC slot array structure improved UC efficiency 240-fold considering absorption and emission enhancements. This double resonance UC improvement can be applied to practical optical devices.
Hierarchical PANI/NiCo-LDH Core-Shell Composite Networks on Carbon Cloth for High Performance Asymmetric Supercapacitor
Authors: Ge Xinjin , He Ying , Plachy Tomas , Kazantseva Natalia , Saha Petr , Cheng Qilin
Published: April 2019

In this work, a facile two-step strategy is adopted to construct hierarchical polyaniline/NiCo-layered double hydroxide (PANI/NiCo-LDH) core-shell composite nanofiber networks on carbon cloth (CC). Three-dimensional (3D) porous PANI nanofiber networks are firstly uniformly anchored on CC by in-situ oxidative polymerization, followed by growth of NiCo-LDH nanoflakes on the crosslinked PANI framework via electrochemical deposition. The morphology and electrochemical properties of PANI/NiCo-LDH composites are controlled by the deposition time of LDH. Benefiting from rapid electron transport and ion diffusion, the well-defined PANI/NiCo-LDH hierarchical composite with 200 s deposition of LDH delivers a large capacitance of 1845 F g−1 at 0.5 A g−1 and excellent cycling stability of 82% capacitance retention after 5000 cycles at a very high current density of 10.0 A g−1. Furthermore, an asymmetric supercapacitor (ASC) assembled with PANI/NiCo-LDH as a positive electrode and activated carbon (AC) as a negative electrode exhibits a high capacitance of 147.2 F g−1 in a potential range from 0 to 1.5 V and superior energy density of 46.0 Wh kg−1 at a power density of 351.6 W kg−1.
Preparation of Multicolor Photoluminescent Carbon Dots by Tuning Surface States
Authors: Jiang Kai , Feng Xiangyu , Gao Xiaolu , Wang Yuhui , Cai Congzhong , Li Zhongjun , Lin Hengwei
Published: April 2019

The achievements of multicolor photoluminescent (PL)-emissive carbon dots (CDs), particularly red to near infrared (NIR), are critical for their applications in optoelectronic devices and bioimaging, but it still faces great challenges to date. In this study, PL emission red-shifts were observed when tartaric acid (TA) was added into m-phenylenediamine (mPD) or o-phenylenediamine (oPD) solutions as carbon sources to prepare CDs, i.e., from blue to green for mPD and from yellow-green to red for oPD. Morphology and structure analyses revealed that the increased surface oxidation and carboxylation were responsible for the red-shifts of emission, indicating that TA played a key role in tuning the surface state of CDs. These factors could be employed as effective strategies to adjust PL emissions of CDs. Consequently, multicolor PL CDs (i.e., blue-, green-, yellow-green- and red-emissive CDs) can be facilely prepared using mPD and oPD in the absence and presence of TA. Particularly, the obtained red-emissive CDs showed a high PL quantum yield up to 22.0% and an emission covering red to NIR regions, demonstrating great potentials in optoelectronic devices and bioimaging. Moreover, multicolor phosphors were further prepared by mixing corresponding CDs with polyvinylpyrrolidone (PVP), among which the blue, green, and red ones could serve as three primary color phosphors for fabricating multicolor and white light-emitting diodes (LEDs). The white LED was measured to show a Commission Internationale de L’Eclairage (CIE) 1931 chromaticity coordinate of (0.34, 0.32), a high color rendering index (CRI) of 89, and a correlated color temperature (CCT) of 5850 K, representing one of the best performances of white LEDs based on CDs.
High-Density Plasmonic Nanoparticle Arrays Deposited on Nanoporous Anodic Alumina Templates for Optical Sensor Applications
Authors: Malinovskis Uldis , Poplausks Raimonds , Erts Donats , Ramser Kerstin , Tamulevičius Sigitas , Tamulevičienė Asta , Gu Yesong , Prikulis Juris
Published: April 2019

This study demonstrates a new, robust, and accessible deposition technique of metal nanoparticle arrays (NPAs), which uses nanoporous anodic alumina (NAA) as a template for capillary force-assisted convective colloid (40, 60, and 80 nm diameter Au) assembly. The NPA density and nanoparticle size can be independently tuned by the anodization conditions and colloid synthesis protocols. This enables production of non-touching variable-density NPAs with controllable gaps in the 20–60 nm range. The NPA nearest neighbor center distance in the present study was fixed to 100 nm by the choice of anodization protocol. The obtained Au NPAs have the resonant scattering maxima in the visible spectral range, with a refractometric sensitivity, which can be tuned by the variation of the array density. The thickness of the NAA layer in an Aluminum-NAA-NPA multilayer system enables further tuning of the resonance frequency and optimization for use with specific molecules, e.g., to avoid absorption bands. Applicability of the mentioned multilayers for colorimetric refractive index (RI) sensing is demonstrated. Their use as Surface-Enhanced Raman Scattering (SERS) substrates is tested using hemoglobin as a biological probe molecule.
Electrospinning Nanofibers for Therapeutics Delivery
Authors: Shahriar S. M. Shatil , Mondal Jagannath , Hasan Mohammad Nazmul , Revuri Vishnu , Lee Dong Yun , Lee Yong-Kyu
Published: April 2019

The limitations of conventional therapeutic drugs necessitate the importance of developing novel therapeutics to treat diverse diseases. Conventional drugs have poor blood circulation time and are not stable or compatible with the biological system. Nanomaterials, with their exceptional structural properties, have gained significance as promising materials for the development of novel therapeutics. Nanofibers with unique physiochemical and biological properties have gained significant attention in the field of health care and biomedical research. The choice of a wide variety of materials for nanofiber fabrication, along with the release of therapeutic payload in sustained and controlled release patterns, make nanofibers an ideal material for drug delivery research. Electrospinning is the conventional method for fabricating nanofibers with different morphologies and is often used for the mass production of nanofibers. This review highlights the recent advancements in the use of nanofibers for the delivery of therapeutic drugs, nucleic acids and growth factors. A detailed mechanism for fabricating different types of nanofiber produced from electrospinning, and factors influencing nanofiber generation, are discussed. The insights from this review can provide a thorough understanding of the precise selection of materials used for fabricating nanofibers for specific therapeutic applications and also the importance of nanofibers for drug delivery applications.
Control of Membrane Fouling in Organics Filtration Using Ce-Doped Zirconia and Visible Light
Authors: Bortot Coelho Fabrício Eduardo , Gionco Chiara , Paganini Maria Cristina , Calza Paola , Magnacca Giuliana
Published: April 2019

Membrane fouling has been a major issue in the development of more efficient water treatment processes. Specifically in surface waters filtration, organic matter, such as humic-like substances, can cause irreversible fouling. Therefore, this study evaluates the activity of a photocatalytic layer composed of Ce-doped zirconia nanoparticles in improving the fouling resistance during filtration of an aqueous solution of humic acid (HA). These nanoparticles were prepared by hydrothermal and sol–gel processes and then characterized. Before the filtration experiments, the photodegradation of HA catalyzed by Ce-doped zirconia nanoparticles in dispersion was studied. It was observed that the sol–gel prepared Ce-ZrO2 exhibited higher HA removal in practically neutral pH, achieving 93% efficiency in 180 min of adsorption in the dark followed by 180 min under visible-light irradiation using light-emitting diodes (LEDs). Changes in spectral properties and in total organic carbon confirmed HA degradation and contributed to the proposal of a mechanism for HA photodegradation. Finally, in HA filtration tests, Ce-ZrO2 photocatalytic membranes were able to recover the flux in a fouled membrane using visible-light by degrading HA. The present findings point to the further development of anti-fouling membranes, in which solar light can be used to degrade fouling compounds and possibly contaminants of emerging concern, which will have important environmental implications.
Photocatalytic Activity of TiO2 Nanofibers: The Surface Crystalline Phase Matters
Authors: Zhang Hongnan , Yu Ming , Qin Xiaohong
Published: April 2019

The crystal phases and surface states of TiO2 can intrinsically determine its performance in the applications of photocatalysis. Here, we prepared TiO2 nanofibers with different crystal phase contents by electrospinning followed via calcination at different temperatures. The TiO2 nanofibers were characterized using scanning electron microscopy (SEM), X-ray diffraction (XRD), Raman spectrometry, transmission electron microscopy (TEM), and photocatalytic performance testing. The results showed that the phases of TiO2 nanofibers were layered, that surface crystal phase transition rate was faster than that of internal layers contributed the difference in the ratio of anatase and rutile in the outer and inner layer of TiO2 nanofibers. The TiO2 nanofibers obtained at 575 °C had the best photocatalytic activity, taking only 25 min to degrade Rhodamine B. At 575 °C, the rutile content of the sample surface was about 80 wt.%, while the internal rutile content was only about 40 wt.%. Subsequently, we prepared two different structures of anatase–rutile core-shell TiO2 nanofibers. The core-shell structure can be clearly seen by TEM characterization. The photocatalytic activity of two kinds of core-shell TiO2 nanofibers was tested. The results showed that the photocatalytic activity was close to that of the pure phase TiO2 nanofibers, which corresponded with the surface phase. This further proves that the photocatalytic activity of the material is mainly affected by its surface structure.
Mimicking the Annulus Fibrosus Using Electrospun Polyester Blended Scaffolds
Authors: Shamsah Alyah H. , Cartmell Sarah H. , Richardson Stephen M. , Bosworth Lucy A.
Published: April 2019

Treatments to alleviate chronic lower back pain, caused by intervertebral disc herniation as a consequence of degenerate annulus fibrosus (AF) tissue, fail to provide long-term relief and do not restore tissue structure or function. This study aims to mimic the architecture and mechanical environment of AF tissue using electrospun fiber scaffolds made from synthetic biopolymers-poly(ε-caprolactone) (PCL) and poly(L-lactic) acid (PLLA). Pure polymer and their blends (PCL%:PLLA%; 80:20, 50:50, and 20:80) are studied and material properties-fiber diameter, alignment, % crystallinity, tensile strength, and water contact angle-characterized. Tensile properties of fibers angled at 0°, 30°, and 60° (single layer scaffolds), and ±0°, ±30°, and ±60° (bilayer scaffolds) yield significant differences, with PCL being significantly stiffer with the addition of PLLA, and bilayer scaffolds considerably stronger. Findings suggest PCL:PLLA 50:50 fibers are similar to human AF properties. Furthermore, in vitro culture of AF cells on 50:50 fibers demonstrates attachment and proliferation over seven days. The optimal polymer composition for production of scaffolds that closely mimic AF tissue both structurally, mechanically, and which also support and guide favorable cell phenotype is identified. This study takes a step closer towards successful AF tissue engineering and a long-term treatment for sufferers of chronic back pain.
Contrast Agents Delivery: An Up-to-Date Review of Nanodiagnostics in Neuroimaging
Authors: Teleanu Daniel Mihai , Chircov Cristina , Grumezescu Alexandru Mihai , Volceanov Adrian , Teleanu Raluca Ioana
Published: April 2019

Neuroimaging is a highly important field of neuroscience, with direct implications for the early diagnosis and progression monitoring of brain-associated diseases. Neuroimaging techniques are categorized into structural, functional and molecular neuroimaging, each possessing advantages and disadvantages in terms of resolution, invasiveness, toxicity of contrast agents and costs. Nanotechnology-based approaches for neuroimaging mostly involve the development of nanocarriers for incorporating contrast agents or the use of nanomaterials as imaging agents. Inorganic and organic nanoparticles, liposomes, micelles, nanobodies and quantum dots are some of the most studied candidates for the delivery of contrast agents for neuroimaging. This paper focuses on describing the conventional modalities used for imaging and the applications of nanotechnology for developing novel strategies for neuroimaging. The aim is to highlight the roles of nanocarriers for enhancing and/or overcome the limitations associated with the most commonly utilized neuroimaging modalities. For future directions, several techniques that could benefit from the increased contrast induced by using imaging probes are presented.
Achieving Ultrahigh Hardness in Electrodeposited Nanograined Ni-Based Binary Alloys
Authors: Zheng Xiangui , Hu Jian , Li Jiongxian , Shi Yinong
Published: April 2019

Annealing hardening has recently been found in nanograined (ng) metals and alloys, which is ascribed to the promotion of grain boundary (GB) stability through GB relaxation and solute atom GB segregation. Annealing hardening is of great significance in extremely fine ng metals since it allows the hardness to keep increasing with a decreasing grain size which would otherwise be softened. Consequently, to synthesize extremely fine ng metals with a stable structure is crucial in achieving an ultrahigh hardness in ng metals. In the present work, direct current electrodeposition was employed to synthesize extremely fine ng Ni-Mo and Ni-P alloys with a grain size of down to a few nanometers. It is demonstrated that the grain size of the as-synthesized extremely fine ng Ni-Mo and Ni-P alloys can be as small as about 3 nm with a homogeneous structure and chemical composition. Grain size strongly depends upon the content of solute atoms (Mo and P). Most importantly, appropriate annealing induces significant hardening as high as 11 GPa in both ng Ni-Mo and Ni-P alloys, while the peak hardening temperature achieved in ng Ni-Mo is much higher than that in ng Ni-P. Electrodeposition is efficient in the synthesis of ultrahard bulk metals or coatings.
Differing Water Intake and Hydration Status in Three European Countries—A Day-to-Day Analysis
Authors: Braun Hans , von Andrian-Werburg Judith , Malisova Olga , Athanasatou Adelais , Kapsokefalou Maria , Ortega Juan , Mora-Rodriguez Ricardo , Thevis Mario
Published: April 2019

Adequate hydration is essential for maintaining health and functionality of the human body. Studies assessing both daily water intake and hydration status are lacking. This study explored data from the European Hydration Research Study (EHRS) and focused on total water intake (TWI), 24 h hydration status, and day-to-day variations in a sample of 573 healthy adults. TWI was assessed by food records and hydration status (urine osmolality and urine volume) was measured from 24 urine samples collected over seven consecutive days. On all weekdays, mean TWI was higher (p < 0.001 for all days) for the German subjects compared to the Greek and Spanish participants. In 37% of the male and 22% of the female subjects, the individual mean TWI was below the European Food Safety Authority (EFSA) recommendation, with 16% men (4% women) being below the EFSA recommendation on every testing day. Twenty-four hour urine osmolality was lower in women compared to men (595 ± 261 vs. 681 ± 237 mOsmol/kg; p < 0.001). More men (40%) showed a urine osmolality ≥800 mOsmol/kg at least on four days of the study period compared to women (26%) and more participants from Spain (46%) compared to Greece (29%) and Germany (11%). A large number of individuals showed an inadequate hydration status on several days per week, which may have a negative health and cognitive impact on daily life.
Pharmacokinetics and Metabolism of Acetyl Triethyl Citrate, a Water-Soluble Plasticizer for Pharmaceutical Polymers in Rats
Authors: Kim Hyeon , Ji Young Seok , Rehman Shaheed Ur , Choi Min Sun , Gye Myung Chan , Yoo Hye Hyun
Published: April 2019

Acetyl triethyl citrate (ATEC) is a water-soluble plasticizer used in pharmaceutical plasticized polymers. In this study, the pharmacokinetics and metabolism of ATEC were investigated using liquid chromatography–tandem mass spectrometry (LC–MS/MS) in rats. Plasma protein precipitation with methanol was used for sample preparation. For chromatographic separation, a C18 column was used. The mobile phases consisted of 0.1% formic acid and 90% acetonitrile, and gradient elution was used. The following precursor-product ion pairs were selected for reaction monitoring analysis: 319.1 m/z → 157 m/z for ATEC and 361.2 m/z → 185.1 m/z for tributyl citrate (internal standard) in positive ion mode. The LC–MS/MS method was fully validated and successfully applied to a pharmacokinetic study of ATEC in rats. The pharmacokinetic study showed that the volume of distribution and mean residence time of ATEC were higher after oral administration than after intravenous administration, pointing to extensive first-pass metabolism and distribution in tissue. In addition, the plasma concentration profile of the postulated metabolites of ATEC was investigated in plasma, urine, and feces. The resulting data indicated that ATEC was extensively metabolized and excreted mainly as metabolites rather than as the parent form. The developed analytical method and the data on the pharmacokinetics and metabolism of ATEC may be useful for understanding the safety and toxicity of ATEC.
A New Hope: Self-Assembling Peptides with Antimicrobial Activity
Authors: Lombardi Lucia , Falanga Annarita , Del Genio Valentina , Galdiero Stefania
Published: April 2019

Peptide drugs hold great promise for the treatment of infectious diseases thanks to their novel mechanisms of action, low toxicity, high specificity, and ease of synthesis and modification. Naturally developing self-assembly in nature has inspired remarkable interest in self-assembly of peptides to functional nanomaterials. As a matter of fact, their structural, mechanical, and functional advantages, plus their high bio-compatibility and bio-degradability make them excellent candidates for facilitating biomedical applications. This review focuses on the self-assembly of peptides for the fabrication of antibacterial nanomaterials holding great interest for substituting antibiotics, with emphasis on strategies to achieve nano-architectures of self-assembly. The antibacterial activities achieved by these nanomaterials are also described.
Assessment of Wind Energy Potential for the Production of Renewable Hydrogen in Sindh Province of Pakistan
Authors: Iqbal Wasim , Yumei Hou , Abbas Qaiser , Hafeez Muhammad , Mohsin Muhammad , Fatima Arooj , Jamali Maqsood , Jamali Mehwish , Siyal Afroze , Sohail Noman
Published: April 2019

In this study, we developed a new hybrid mathematical model that combines wind-speed range with the log law to derive the wind energy potential for wind-generated hydrogen production in Pakistan. In addition, we electrolyzed wind-generated power in order to assess the generation capacity of wind-generated renewable hydrogen. The advantage of the Weibull model is that it more accurately reflects power generation potential (i.e., the capacity factor). When applied to selected sites, we have found commercially viable hydrogen production capacity in all locations. All sites considered had the potential to produce an excess amount of wind-generated renewable hydrogen. If the total national capacity of wind-generated was used, Pakistan could conceivably produce 51,917,000.39 kg per day of renewable hydrogen. Based on our results, we suggest that cars and other forms of transport could be fueled with hydrogen to conserve oil and gas resources, which can reduce the energy shortfall and contribute to the fight against climate change and global warming. Also, hydrogen could be used to supplement urban energy needs (e.g., for Sindh province Pakistan), again reducing energy shortage effects and supporting green city programs.
The Two-Way Street of Open Access Journal Publishing: Flip It and Reverse It
Authors: Matthias Lisa , Jahn Najko , Laakso Mikael
Published: April 2019

As Open access (OA) is often perceived as the end goal of scholarly publishing, much research has focused on flipping subscription journals to an OA model. Focusing on what can happen after the presumed finish line, this study identifies journals that have converted from OA to a subscription model, and places these “reverse flips” within the greater context of scholarly publishing. In particular, we examine specific journal descriptors, such as access mode, publisher, subject area, society affiliation, article volume, and citation metrics, to deepen our understanding of reverse flips. Our results show that at least 152 actively publishing journals have reverse-flipped since 2005, suggesting that this phenomenon does not constitute merely a few marginal outliers, but instead a common pattern within scholarly publishing. Notably, we found that 62% of reverse flips (N = 95) had not been born-OA journals, but had been founded as subscription journals, and hence have experienced a three-stage transformation from closed to open to closed. We argue that reverse flips present a unique perspective on OA, and that further research would greatly benefit from enhanced data and tools for identifying such cases.
Transparent Attribution of Contributions to Research: Aligning Guidelines to Real-Life Practices
Authors: Matarese Valerie , Shashok Karen
Published: April 2019

Research studies, especially in the sciences, may benefit from substantial non-author support without which they could not be completed or published. The term “contributorship” was coined in 1997 to recognize all contributions to a research study, but its implementation (mostly in biomedical reports) has been limited to the inclusion of an “Author Contributions” statement that omits other contributions. To standardize the reporting of contributions across disciplines, irrespective of whether a given contribution merits authorship or acknowledgment, the Contributor Roles Taxonomy (CRediT) was launched in 2014. Our assessment, however, shows that in practice, CRediT is a detailed authorship classification that risks denying appropriate credit for persons who contribute as non-authors. To illustrate the shortcomings in CRediT and suggest improvements, in this article we review key concepts of authorship and contributorship and examine the range of non-author contributions that may (or may not) be acknowledged. We then briefly describe different types of editorial support provided by (non-author) translators, authors’ editors and writers, and explain why it is not always acknowledged. Finally, we propose two new CRediT taxa and revisions to three existing taxa regarding both technical and editorial support, as a small but important step to make credit attribution more transparent, accurate and open.
Designing Away Waste: A Comparative Analysis of Urban Reuse and Remanufacture Initiatives
Authors: Ordóñez Isabel , Rexfelt Oskar , Hagy Shea , Unkrig Luisa
Published: April 2019

In order to transform the economy into one that is circular, that recovers most materials through reuse, remanufacturing and recycling, these activities need to grow significantly. Waste management has substantially incorporated recycling as an end-of-life treatment but has still largely failed to incorporate remanufacturing and reuse as possible material recovery routes. This article aims to provide useful information to establish centers for urban remanufacture (CUREs), by analyzing fifteen existing initiatives that facilitate reuse and remanufacture by providing access to secondary materials or manufacturing tools. The study consists of a review of selected initiatives complemented with targeted interviews to fill in missing information. Most initiatives provided access to secondary materials (13 of 15 initiatives), and almost all used different manufacturing tools (14 of 15 initiatives). Besides their regular opening hours, initiatives were mainly engaged in capacity building activities, which were done through predefined or improvised workshops. Most initiatives relied on external support to finance their operations (9 of 15 initiatives). However, one of the self-financed initiatives is the oldest initiative in the study, operating since 1998. Based on the results and tacit knowledge collected in this study, a framework is suggested to serve as a guide for establishing future CUREs.
Urban Water Security Assessment Using an Integrated Metabolism Approach—Case Study of the National Capital Territory of Delhi in India
Authors: Ghosh Ruchira , Kansal Arun , Venkatesh G
Published: April 2019

Water is a non substitutable resource and a social good, which governments must perforce provide to its citizens in the right quantity and quality. An integrated urban metabolism model is useful in understanding the status quo of an urban water and sanitation system. By defining and measuring the values of relevant hydrological performance indicators—deliverables of the model referred to—a thorough knowledge of the present performance and the gaps, which need to be plugged en route to a sustainable urban water infrastructure, can be obtained, as demonstrated in this paper. This then forms the bedrock for decision-making and policy formulation for change to be introduced top-down as well as advice, which would enable the much needed bottom-up support to policies. The authors have chosen Delhi as the case study city, but would like to point out that this application can be reproduced for any other town/city/region of the world. The water balance within the chosen system boundaries shows that the annual unutilized flows, amounting to 1443 million cubic meters, dominate the metabolic flows of water in Delhi, and the annual groundwater withdrawal, which exceeds 420 million cubic meters, is much greater than the recharge rate, resulting in a rapid depletion of the groundwater level. There is an urgent need thereby to improve the rate of infiltration of stormwater and reduce the rate of runoff by focusing on increasing the share of permeable surfaces in the city, as well as to consider the wastewater streams as potential sources of water, while not forgetting demand side of management measures, as the pressure on the urban water system in the city is likely to intensify with a combination of population growth, economic development, and climate change in the near future. The recommendations provided by the authors towards the end of the article, can, if suitable measures are undertaken and robust policies are implemented, result in Delhi’s enjoying a water surplus in the short term, and progressively attain complete sustainability with regard to the utilization of its water resources.
Asymptotically Normal Estimators of the Ruin Probability for Lévy Insurance Surplus from Discrete Samples
Authors: Shimizu Yasutaka , Zhang Zhimin
Published: April 2019

A statistical inference for ruin probability from a certain discrete sample of the surplus is discussed under a spectrally negative Lévy insurance risk. We consider the Laguerre series expansion of ruin probability, and provide an estimator for any of its partial sums by computing the coefficients of the expansion. We show that the proposed estimator is asymptotically normal and consistent with the optimal rate of convergence and estimable asymptotic variance. This estimator enables not only a point estimation of ruin probability but also an approximated interval estimation and testing hypothesis.
RAVAN: CubeSat Demonstration for Multi-Point Earth Radiation Budget Measurements
Authors: Swartz William H. , Lorentz Steven R. , Papadakis Stergios J. , Huang Philip M. , Smith Allan W. , Deglau David M. , Yu Yinan , Reilly Sonia M. , Reilly Nolan M. , Anderson Donald E.
Published: April 2019

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) 3U CubeSat mission is a pathfinder to demonstrate technologies for the measurement of Earth’s radiation budget, the quantification of which is critical for predicting the future course of climate change. A specific motivation is the need for lower-cost technology alternatives that could be used for multi-point constellation measurements of Earth outgoing radiation. RAVAN launched 11 November 2016, into a nearly 600-km, Sun-synchronous orbit, and collected data for over 20 months. RAVAN successfully demonstrates two key technologies. The first is the use of vertically aligned carbon nanotubes (VACNTs) as absorbers in broadband radiometers for measuring Earth’s outgoing radiation and the total solar irradiance. VACNT forests are arguably the blackest material known and have an extremely flat spectral response over a wide wavelength range, from the ultraviolet to the far infrared. As radiometer absorbers, they have greater sensitivity for a given time constant and are more compact than traditional cavity absorbers. The second technology demonstrated is a pair of gallium phase-change black body cells that are used as a stable reference to monitor the degradation of RAVAN’s radiometer sensors on orbit. Four radiometers (two VACNT, two cavity), the pair of gallium black bodies, and associated electronics are accommodated in the payload of an agile 3U CubeSat bus that allows for routine solar and deep-space attitude maneuvers, which are essential for calibrating the Earth irradiance measurements. The radiometers show excellent long-term stability over the course of the mission and a high correlation between the VACNT and cavity radiometer technologies. Short-term variability—at greater than the tenths-of-a-Watt/m2 needed for climate accuracy—is a challenge that remains, consistent with insufficient thermal knowledge and control on a 3U CubeSat. There are also VACNT–cavity biases of 3% and 6% in the Total and SW channels, respectively, which would have to be overcome in a future mission. Although one of the black bodies failed after four months, the other provided a repeatable standard for the duration of the project. We present representative measurements from the mission and demonstrate how the radiometer time series can be used to reconstruct outgoing radiation spatial information. Improvements to the technology and approach that would lead to better performance and greater accuracy in future missions are discussed.
Predicting Forest Inventory Attributes Using Airborne Laser Scanning, Aerial Imagery, and Harvester Data
Authors: Saukkola Atte , Melkas Timo , Riekki Kirsi , Sirparanta Sanna , Peuhkurinen Jussi , Holopainen Markus , Hyyppä Juha , Vastaranta Mikko
Published: April 2019

The aim of the study was to develop a new method to use tree stem information recorded by harvesters along operative logging in remote sensing-based prediction of forest inventory attributes in mature stands. The reference sample plots were formed from harvester data, using two different tree positions: harvester positions (XYH) in global satellite navigation system and computationally improved harvester head positions (XYHH). Study materials consisted of 158 mature Norway-spruce-dominated stands located in Southern Finland that were clear-cut during 2015–16. Tree attributes were derived from the stem dimensions recorded by the harvester. The forest inventory attributes were compiled for both stands and sample plots generated for stands for four different sample plot sizes (254, 509, 761, and 1018 m2). Prediction models between the harvester-based forest inventory attributes and remote sensing features of sample plots were developed. The stand-level predictions were obtained, and basal-area weighted mean diameter (Dg) and basal-area weighted mean height (Hg) were nearly constant for all model alternatives with relative root-mean-square errors (RMSE) roughly 10–11% and 6–8%, respectively, and minor biases. For basal area (G) and volume (V), using either of the position methods, resulted in roughly similar predictions at best, with approximately 25% relative RMSE and 15% bias. With XYHH positions, the predictions of G and V were nearly independent of the sample plot size within 254–761 m2. Therefore, the harvester-based data can be used as ground truth for remote sensing forest inventory methods. In predicting the forest inventory attributes, it is advisable to utilize harvester head positions (XYHH) and a smallest plot size of 254 m2. Instead, if only harvester positions (XYH) are available, expanding the sample plot size to 761 m2 reaches a similar accuracy to that obtained using XYHH positions, as the larger sample plot moderates the uncertainties when determining the individual tree position.
Seasonal Variability of Retroflection Structures and Transports in the Atlantic Ocean as Inferred from Satellite-Derived Salinity Maps
Authors: Castellanos Paola , Olmedo Estrella , Pelegrí Josep Lluis , Turiel Antonio , Campos Edmo J. D.
Published: April 2019

Three of the world’s most energetic regions are in the tropical and South Atlantic: the North Brazil Current Retroflection, the Brazil-Malvinas Confluence, and the Agulhas Current Retroflection. All three regions display offshore diversions of major boundary currents, which define the intensity of the returning limb of the Atlantic meridional overturning circulation. In this work, we use a sea-surface salinity (SSS) satellite product, combined with a high-resolution numerical model and in situ measurements, in order to explore the seasonal variation of the surface currents and transports in these three regions. The analysis of the model output shows that the SSS patterns reflect the surface velocity structure, with the largest horizontal SSS gradients coinciding with those areas of highest velocity and the most predominant velocity vector being 90° anticlockwise (clockwise) from the horizontal SSS gradient in the northern (southern) hemisphere. This information is then applied to the SSS satellite product to obtain maps of water velocity and salt transports, leading to a quantitative tool to estimate both water and salt transports in key regions of the world ocean.
Bibliometric Analysis of Remote Sensing Research Trend in Crop Growth Monitoring: A Case Study in China
Authors: Wang Lijuan , Zhang Guimin , Wang Ziyi , Liu Jiangui , Shang Jiali , Liang Liang
Published: April 2019

Remote sensing of crop growth monitoring is an important technique to guide agricultural production. To gain a comprehensive understanding of historical progression and current status, and future trend of remote sensing researches and applications in the field of crop growth monitoring in China, a study was carried out based on the publications from the past 20 years by Chinese scholars. Using the knowledge mapping software CiteSpace, a quantitative and qualitative analysis of research development, current hotspots, and future directions of crop growth monitoring using remote sensing technology in China was conducted. Furthermore, the relationship between high-frequency keywords and the emerging hot topics were visually analyzed. The results revealed that Chinese researchers paid more attention on keywords such as “vegetation index”, “crop growth”, “winter wheat”, “leaf area index (LAI)”, and “model” in the field of crop growth monitoring, and “LAI” and “unmanned aerial vehicle (UAV)”, appeared increasingly in frontier research of this discipline. Overall, bibliometric results from this CiteSpace-aided study provide a quantitative visualization to enrich our understanding on the historical development, current status, and future trend of crop growth monitoring in China.
Retrieval of Sea Surface Wind Speeds from Gaofen-3 Full Polarimetric Data
Authors: Zhang Tianyu , Li Xiao-Ming , Feng Qian , Ren Yongzheng , Shi Yingni
Published: April 2019

In this paper, the sea surface wind speed (SSWS) retrieval from Gaofen-3 (GF-3) quad-polarization stripmap (QPS) data in vertical-vertical (VV), horizontal-horizontal (HH), and vertical-horizontal (VH) polarizations is investigated in detail based on 3170 scenes acquired from October 2016 to May 2018. The radiometric calibration factor of the VV polarization data is examined first. This calibration factor generally meets the requirement of SSWS retrieval accuracy with an absolute bias of less than 0.5 m/s but shows highly dispersed characteristics. These results lead to SSWS retrievals with a small bias of 0.18 m/s, but a rather high root mean square error (RMSE) of 2.36 m/s when compared with the ERA-Interim reanalysis model data. Two refitted polarization ratio (PR) models for the QPS HH polarization data are presented. Based on a combination of the incidence angle-dependent and azimuth angle-dependent PR model and CMOD5.N, the SSWS derived from the QPS HH data shows a bias of 0.07 m/s and an RMSE of 2.26 m/s relative to the ERA-Interim reanalysis model wind speed. A linear function relating SSWS and the normalized radar cross section (NRCS) of QPS VH data is derived. The SSWS data retrieved from the QPS VH data show good agreement with the WindSat SSWS data, with a bias of 0.1 m/s and an RMSE of 2.02 m/s. We also apply the linear function to the GF-3 Wide ScanSAR data acquired for the typhoon SOULIK, which yields very good agreement with the model results. A comparison of SSWS retrievals among three different polarization datasets is also presented. The current study and our previous work demonstrate that the general accuracy of the SSWS retrieval based on GF-3 QPS data has an absolute bias of less than 0.3 m/s and an RMSE of 2.0 ± 0.2 m/s relative to various datasets. Further improvement will depend on dedicated radiometric calibration efforts.