bluuebunny/crossref_metadata_2025 huggingface dataset:
Religião contra democracia
Authors: Barrera Rivera Paulo
Published: January 2022

A participação de evangélicos na política é um fenómeno que se tornou comum na América Latina no período posterior às ditaduras. O presente artigo analisa o fenômeno, mais recente, de apoio de evangélicos/as a candidaturas e projetos políticos da extrema direita que configuram um “neoconservadorismo religioso”. Focamos nossa atenção na prática política de evangélicos no Peru, no período contemporâneo ao governo de Donald Trump quem acolheu à transnacional política religiosa “Capitol Ministries”. Analisamos a compreensão do poder político na tradição evangélica e os argumentos teológicos de sua militância na extrema direita. Apoiamo-nos em levantamento etnográfico remoto de material de campanha eleitoral do partido “Renovação Popular” e de seus candidatos pastores nas eleições de 2021 no Peru. Trabalhamos com a hipótese de que a compreensão que os evangélicos têm do poder político reduz o espaço democrático quando transforma adversários em inimigos que devem ser “exterminados”, semelhante ao fenômeno Bolsonaro no Brasil.
Jornada nas escolas
Authors: Giraffa Lucia Maria Martins
Published: January 2022

Este artigo apresenta reflexões acerca da questão da formação docente e uso de TD integradas no espaço presencial e virtual buscando discutir aspectos do estereotipo relacionado aos alunos nativos digitais e professores imigrantes digitais. Nosso estudo considera aspectos relacionados aos mitos e desafios da formação docente e a organização da estrutura escolar no contexto da cibe cultura. Esta reflexão é resultante de várias investigações levadas a termo no âmbito do programa de pós-graduação em educação da FACED/PUCRS associado à linha de pesquisa sobre educação, tecnologia e formação de professores e sistematizadas na disciplina Cibe cultura e Formação Docente ministrada pela autora.
BLOG
Authors: Real Luciane Magalhães Corte , Stepanski Luciane Marilei Pereira
Published: January 2022

A construção do processo da escrita tem sido um desafio desde a Educação Infantil até a Universidade. Em sala de aula, a cópia ainda é uma das metodologias mais utilizadas pelos docentes; os discentes “copiam do quadro”. O presente estudo foi realizado junto ao laboratório de informática com alunos de uma Escola Pública no sul do Brasil. Participaram da pesquisa 10 turmas das seguintes etapas da educação básica: ensino fundamental, ensino médio e alunos pertencentes à classe de aceleração. Neste artigo foram enfocados o estudo com uma turma do quarto ano. Trata-se de uma pesquisa qualitativa na forma de estudo de caso cujo objetivo foi a análise da construção da escrita dos alunos e a leitura no Blog da turma. As produções escritas analisadas foram uma carta; um livro; a escrita coletiva sobre tecnologias; reflexões sobre um filme e interpretações de leituras de um livro. Foram levantadas categorias para compreender a construção da escrita dos alunos. Também foram analisadas entrevistas executadas no final do projeto, que indicaram a preferência dos educandos ao escrever no computador, porque: “na sala de aula tem que olhar para o quadro e copiar”; “na informática tem que pensar”; “pode pesquisar para melhorar” entre outras verbalizações. Assim, a análise dos dados apontou para a escrita online, como uma possibilidade de desempenhar um percurso de escrita autônoma, com recursos que podem auxiliar o educando a desenvolver com mais propriedade sua criatividade e protagonismo dentro do processo de ensino-aprendizagem; valorizando sua escrita através da leitura compartilhada.
USO DE LAS TÉCNICAS DE RECOLECCIÓN DE LA INFORMACIÓN EN UNA AUDITORÍA FORENSE
Authors:   Universidad Cooperativa de Colombia, MORENO JOHN , GUIFO HEBER , DUCUARA ANGIE , SANDOVAL LAURA
Published: January 2022

The objective of this article is to analyze the techniques for collecting financial information and its impact on a forensic audit assignment. At the methodological lévele, this research is descriptive and documentary. As a result, it is evident that the use of the techniques of gathering financial information in a forensic audit are of utmost importance for the veracity, trustworthiness, objectivity and accuracy of the same, even more so when the entrepreneur, besides looking for the economic value of the fraud and the evidence for a criminal process, which seeks is to find flaws in internal controls, and for this the risks matrix, shows how specialized and traditional techniques help in the order of forensic audit.
LA AUDITORÍA FORENSE Y EL PENTÁGONO DEL FRAUDE
Authors:   Universidad Cooperativa de Colombia, HERNANDEZ LUDIVIA , LONDOÑO ANGELA , VARGAS KATHERINE , GUTIERREZ FERNANDO , FLOREZ MARIO
Published: January 2022

This article analyzes the order of the forensic audit and its incidence against the pentagon of fraud. Methodologically it is a descriptive study, therefore, the role of forensic auditing against the pentagon of fraud and the characteristics or variables that surround it are studied: motivation, pressure, rationalization, capacity and opportunity. As a result, it is considered that fraud arises from the person, the processes and the environment, that is why internal con- trol must be focused on these three factors, evaluating in each one if there is any sign that indicates the emergence of any of the characteristics of the pentagon that causes fraud.
GUÍA EN LENGUAJE COLOQUIAL SOBRE REQUERIMIENTOS IMPUESTOS POR LA UNIDAD DE GESTIÓN PARAFISCAL Y PENSIONAL (UGPP) PARA EMPRESARIOS DEL COMÚN
Authors:   Corporación Universitaria Republicana, LOPEZ NATALIA , MORENO NIDIA
Published: January 2022

The UGPP is an entity that is responsible for ensuring contributions from legal and natural persons required to make contributions to the parafiscal and pension system in Colombia. Therefore, this investigation will allow to know, analyze, and conclude the causes and types of the most common requirements imposed by the UGPP, as well as the acquittal and sanctioning imposition by the entity based on real cases.
DESARROLLO DE UN PLAN DE LOGÍSTICA INTERNA PARA LA DISTRIBUCIÓN Y ALMACENAMIENTO DE MERCANCÍA EN LA BODEGA DE TECHNOLOGY WORLD GROUP S.A.S
Authors:   Universidad  Libre, RUÍZ MARTÍNEZ MARÍA , VELOZA SERGIO , FUENTES EVER
Published: January 2022

A good logistics plan generates within companies an adequate development of their activities without having any inconvenience, which implies improving the quality of the company and its growth in the industrial and commercial world. The proposed project will generate a favorable performance and structuring in order to allow managers to direct and make decisions with greater efficiency in relation to the operation of the company and its logistics planning, orienting the processes to a better execution of the warehouses and the management of the distribution and storage of equipment, minimizing bottlenecks, reprocessing and actions that increase costs and waste the organization’s resources. On the other hand, the proposed methodology is based on the union of the different procedures carried out in the operational area and the interrelation with processes of the commercial and administrative area, to improve the execution of the procedures for the reception and dispatch of orders requested by distributors and stores, reducing the percentage level of errors made by mismanagement and control of the main Technology World Group warehouse. S.A.S.
RACIONALIZACIÓN DE LOS PROCESOS EN LA REVISIÓN FÍSICA DE INVENTARIOS EN EL ÁREA DE ALMACENAMIENTO DE PRODUCTOS TERMINADOS GARANTIZANDO LA SEGURIDAD Y SALUD EN EL TRABAJO
Authors:   Universidad Libre, LINARES ANGIE , AGUIRRE YESICA , MAYORGA MANUEL
Published: January 2022

The company on which this study was carried out performs a technical review of the inventory once a month, with a level of confidence and accuracy of 100%, although its level of precision is very high, it is necessary to change the how nventory control is being executed, since the current method exposes the operator to unnecessary and infallible risk, which has motivated the operations manager to request a change in the process. However, the process with which the inventory is currently being verified requires more man hours and the payment of overtime to its workers to complete the activity, generating an increase in nominal costs. For this reason, the objective of this work is to optimize the method of operation in the physical review of the inventory, allowing it to improve its effectiveness, reduce nominal costs, execution times and guaranteeing safety and health at work. Therefore, the work was carried out through descriptive applied research, developing strategies that start from theories, in order to apply them and thus give an optimal solution to the problems found in the company. Likewise, a quantitative investigation was implemented where the data emerged from a field work carried out in the finished product storage area, through a study of times and movements in the inventory review. Additionally, a cost analysis was carried out, accompanied by various simulations that made it possible to establish which is the appropriate machinery for the process. As a result, it was determined that the drone and the zigzag method is the optimal solution for the physical review of inventory by reducing risks, costs and execution times.
DISSOLUTION PROFILE OF METRONIDAZOLE TABLET IN DIVERSE FATTY MEDIUMS
Authors:   samina alam, nawab Amber
Published: January 2022

The aim of the study was to confirm the interaction of food with metronidazole 400 mg tablet with diverse dissolution medium like milk, oil and gastric fluid to observe the effects of physiological changes in terms of absorbance.
EVALUATION OF KNOWLEDGE, ATTITUDE PERCPTION TOWARDS TEXT NECK SYNDROME AMONG POPULATION: A CROSS SECTIONAL STUDY
Authors:   iqra bashir, alam samina
Published: January 2022

Text neck is a syndrome that is described by repetitive stress injury and pain in the neck. It is a health condition that is developed by using a mobile phone or watching any handheld device for a prolonged period of time. It is commonly found in children. The risk factor of developing text neck is abnormally stretching the muscles and tendons of your neck which puts pressure on nerves in your back.
EVALUATION OF KNOWLEDGE, ATTITUDE AND PERCEPTION TOWARDS FIFTH DISEASE AMONG POPULATION: A CROSSSECTIONAL STUDY
Authors:   maira mahmood, alam samina
Published: January 2022

Fifth disease is a viral disease caused by parovirus B19, also called erythema infection. It is commonly present in children and pregnant women it can be transferred from mother to fetus, it caused rashes on skin, legs and neck and it seems like “slapped cheeks” on children face. The risk factor increase when the infected person sneezed, coughed or by their blood products. It may cause severe anemia and the may need blood transfusion. An overview on account systemic reviews on fifth disease a survey is conducted. About 150 persons participated by attending our questionnaire.
RESPON IMPLEMENTASI BAHAN AJAR DIGITAL “流利说汉语” [liúlì shuō hànyǔ] PADA PEMBELAJARAN BAHASA MANDARIN KELAS X DI SMAN 2 MALANG
Authors: VENTIVANI AIGA , Lukluk Ul Muyassaroh  , Octi Rjeky Mardasari
Published: January 2022

Penelitian ini dilakukan untuk mengetahui respon implementasi bahan ajar digital Bahasa Mandarin “流利说汉语” [liúlì shuō hànyǔ]. Jenis penelitian yang digunakan dalam penelitian ini adalah penelitian kualitatif. Penelitian ini menggunakan instrumen pendukung berupa lembar angket terbuka yang disebar melalui google form. Sumber data penelitian ini adalah guru pengampu mata pelajaran Bahasa Mandarin dan siswa SMA kelas X lintas minat SMAN 2 Malang. Data dalam penelitian ini merupakan hasil lembar angket terbuka yang diisi oleh guru pengampu mata pelajaran Bahasa Mandarin dan siswa SMA kelas X. Hasil dari penelitian ini yaitu respon siswa dan guru Bahasa Mandarin terhadap implementasi bahan ajar digital “流利说汉语” [liúlì shuō hànyǔ]pada pembelajaran Bahasa Mandarin mendapatkan respon positif. Terdapat saran yang diberikan oleh peneliti agar penggunaan bahan ajar digital tersebut dapat digunakan secara maksimal. Bahan ajar tersebut lebih baik digunakan mengunakan jaringan internet agar dapat mengoperasikan video didalamnya, Saran selanjutnya yaitu untuk pengembang selanjutnya agar dapat mengembangkan bahan ajar sejenis yang dapat digunakan secara offline dan materi lainnya yang sesuai dengan Kurikulum yang berlaku.
Current and predicted temperatures impair reproduction in the Australian sheep flock
Authors: Wettere William van , Culley Sam , Swinbourne Alyce , Leu Stephan , Lee Stephen , Weaver Alice , Kelly Jennifer , Walker Simon , Kleemann David , Thomas Dane , Hayman Peter , Gatford Kathryn , Kind Karen , Westra Seth
Published: January 2022

Climate change threatens global livestock production1,2. We modelled the impact of recent temperatures and a 1°C and 3°C temperature increase over the historical baseline on risks of heat stress at key periods of the reproductive cycle and consequences for reproduction across the entire Australian sheep flock. We estimate that 2.1 million potential lambs are currently lost annually due to heat stress, increasing to 2.5 and 3.3 million as temperatures rise.
Influencing Factors of Intention and Behavior of Patient Delay in Elderly Benign Prostatic Hyperplasia: a Descriptive Qualitative Study
Authors: Zou Hao , Jiang Dong-xu , Zhao Wan-yue , Jia Hong-hong , Li Ying-li , Yang Jin-hong , Zhang Lin-lin
Published: January 2022

Background: Most elderly patients with BPH have experienced patient delay. Based on the TPB, the aim of this study was to describe the influencing factors of BPH patients' intention and behavior of patient delay and to provide a reference for the development of a patient delay intention scale and personalized intervention.Methods: This descriptive qualitative study was carried out 4 months in 2021 in China. The participants were 20 patients with BPH ages 60 to 82 years old who experienced patient delay and were selected through purposive sampling method. The study was performed in a large general hospital and a community hospital. The data were collected via face-to-face semi-structured interviews.Results: The following themes were relevant to BPH patients with intention and behavior of patient delay: “Insufficient cognition of symptoms (low symptom alertness, symptom benign attribution)”, “Experience coping instead of going to a doctor”, “Negative attitude toward seeking medical care (Underestimation of the consequences of delayed medical treatment, Negative evaluation of early medical treatment)”, “The influence of others on decision-making for seeking medical care(People who approve or disapprove of going to a doctor, Do or do not follow the opinions of others)”, “Obstacles to seeking medical care(Factors from the patient, Factors from medical institutions)”Conclusion: The delay was longer in rural areas than in urban areas. BPH patients' intention and behavior of patient delay are the result of a combination of many factors. Therefore, it is recommended to develop a scale to evaluate the patient delay intention for BPH, and provide personalized interventions based on the scale to improve patient delay in elderly BPH patients
Feasibility of using a General Health Promotion Approach to Helping Smokers with Non- Communicable Diseases Quit Smoking: A Randomized Controlled Trial
Authors: LI William Ho Cheung , HO Laurie Long Kwan , CHEUNG Ankie Tan , WONG Man Ping , CHEUNG Derek Yee Tak , LUO Yuan-hui , XIA Wei , LAM Tai Hing
Published: January 2022

This randomized controlled trial aimed to evaluate the efficacy and ascertain the feasibility of a general health promotion approach that uses instant messaging to deliver brief motivational interviewing to help smokers with non-communicable diseases quit smoking. A total of 60 participants who had medical follow-up in a special out-patient clinic were randomized into two groups, 30 in the intervention group received brief motivational interviewing to assist them with their chosen behavioral changes, and 30 in the control group received only a smoking cessation booklet. The primary outcome, by intention-to-treat, was biochemically validated abstinence at 12 months. The intervention group had a higher biochemically validated abstinence rate than the control group at 12 months (16.7% vs 6.7% P=.23) although the difference was not statistically significant (Adjusted OR 2.4, 95% CI 0.43–13.75; P=.32). In addition, the intervention group had a significantly higher self-reported reduction of at least 50% in daily cigarette consumption than the control group at 6 months (Adjusted OR 7.2, 95% CI 1.22–42.44; P=.03).This study demonstrated the potential efficacy and feasibility of a general health promotion approach that uses instant messaging to deliver brief motivational interviewing to help smokers with non-communicable diseases quit smoking.
Coverage and Determinants of Infant Postnatal Care in Nigeria: a Population-based Cross-sectional Study
Authors: Egbewale Bolaji E. , Oyedeji Olusola A. , Bump Jesse , Sudfeld Christopher
Published: January 2022

Background: In 2019, Nigeria had the most under-5 child deaths globally, many of which occurred within the neonatal period, especially in the first week after birth. Despite the effectiveness of infant postnatal care (PNC) attendance recommended by the World Health Organization (WHO), this problem persists. Therefore, the study examined coverage and determinants of infant PNC attendance in Nigeria. Methods: Nigeria Demographic Health Survey (NDHS) 2018 data were used to evaluate infant PNC coverage and determinants. Infant PNC was defined as receipt of care within two days of birth. Children delivered up to two years before the 2018 NDHS were included. We examined predictors of infant PNC with Poisson regression models to estimate relative risks (RR).Results: The national coverage of infant PNC was 37.3% (95% CI: 35.8%–38.7%). Significant heterogeneity in PNC attendance exists at state and regional levels. Facility delivery was strongly associated with uptake of PNC (RR: 6.07; 95% CI: 5.60–6.58). Greater maternal education, maternal employment, urban residence, female head of household, and greater wealth were also associated with increased likelihood of PNC visits. Conclusions: Uptake of infant PNC in Nigeria is low. Interventions are urgently needed to promote equity in access and increase demand.
Electrical Stimulation Attenuates Disuse Muscular Atrophy by Modulating Endoplasmic Reticulum Stress-induced Parkin-dependent Mitophagy
Authors: Zhang Quan-Bing , Liu A-Ying , Fang Qiao-Zhou , Zhang Hai-Yang , Wang Feng , Huang Peng-Peng , Xu Qi-Yu , Wang Hua , Zhou Yun
Published: January 2022

Background: The aim of this study was to investigate the therapeutic effect of electrical stimulation on disuse muscular atrophy in a rabbit model of knee joint contracture and explore the role of endoplasmic reticulum stress-induced Parkin-dependent mitophagy in this process.Methods: Two sub-experiments were carried out successively in our study. In the first sub-experiment, 24 rabbits were divided into four groups on average based on the immobilization time: Ctrl 1, I-2, I-4, and I-6 groups. In the second sub-experiment, 24 rabbits were also divided into four groups on average in accordance with the process mode: Ctrl2, ES, NR, and EST groups. To test the time-dependent changes of the rectus femoris muscles after immobilization in rabbits, and to evaluate the effect of electrical stimulation on the atrophic rectus femoris muscles, the wet weights of rectus femoris muscles were assessed in this study, along with the protein levels of atrogin-1, p-PERK, Parkin and COXIV.Results: The wet weights of rectus femoris muscles, the protein levels of atrogin-1, p-PERK and Parkin increased after immobilization. It was also revealed that the protein levels of COXIV decreased after immobilization. Electrical stimulation was effective against muscle atrophy, the elevated expression of atrogin-1, p-PERK, Parkin, and the decreased expression of COXIV.Conclusions: Immobilization of unilateral lower limb could induce rectus femoris muscle atrophy, endoplasmic reticulum stress and Parkin mediated mitophagy. Endoplasmic reticulum stress-induced Parkin-dependent mitophagy may be one of the mechanisms by which electrical stimulation can play a significant role.
Gottfriedia Endophyticus sp. nov., a Novel Indole-Acetic Acid Producing Bacterium Isolated From The Roots of Rice Plant
Authors: Chhetri Geeta , Kim Inhyup , Seo Taegun
Published: January 2022

A Gram-stain-positive, aerobic, motile and rod-shaped bacterium, designated RG28T, was isolated from the roots of rice plant collected from paddy fields in Goyang, South Korea. Cells of the strain were oxidase-negative but catalase-positive. Strain RG28T was found to grow at 10–50°C (optimum, 25–30°C), pH 5.0–10.0 (optimum, pH 7.0) and in 1.0–5.0 % (w/v) NaCl (optimum, 0%). The cell-wall peptidoglycan contained meso-diaminopimelic acid and the predominant menaquinones were MK-7 and MK-6.The predominant cellular fatty acids were C16:0, iso-C15:0 and anteiso-C15:0. The major polar lipids included phosphatidylethanolamine, diphosphatidylglycerol, phosphatidylglycerol, four unidentified aminophosphoglycolipids, four unidentified aminophospholipids, two unidentified glycolipids, one unidentified aminoglycolipid and four unidentified lipids. The genomic DNA G+C content was 33.5 mol%. Phylogenetic analysis based on 16S rRNA gene sequences showed that the strain was closely related to Gottfriedia acidiceleris CBD 119T (98.6%), Gottfriedia solisilvae LMG 18422T (98.5 %) and Gottfriedia luciferensis LMG 18422T (98.4 %). The average nucleotide identity (ANI) and in silico DNA–DNA hybridization (isDDH) values between strain RG28T and type strains of Gottfriedia species were lower than the cut-offs (≥95–96 % for ANI and ≥70 % for isDDH) required to define a bacterial species. Meanwhile, the strain has the ability to produce indole-acetic acid (40.5 µg/mL). Phylogenetic, physiological and chemotaxonomic data suggested that strain RG28T represented a novel species of the genus Gottfriedia, for which the name Gottfriedia endophyticus sp. nov. is proposed, with the type strain RG28T (=KCTC 43327T=TBRC 15151T).Repositories: The draft genome and 16S rRNA gene sequences of strain RG28T have been deposited in GenBank/EMBL/DDBJ under accession numbers JAGIYQ000000000 and MW386408 respectively.
TRF-Val-CAC-016 Modulates the Transduction of CACNA1d-Mediated MAPK Signaling Pathways to Suppress the Proliferation of Gastric Carcinoma
Authors: Xu Weiguo , Zheng Junyu , Wang Xiao , Zhou Bin , Chen Huanqiu , Li Gang , Yan Feng
Published: January 2022

Background: As a new kind of non-coding RNAs (ncRNAs), tRNA derivatives play an important role in gastric carcinoma (GC). Nevertheless, the underlying mechanism tRNA derivatives were involved in was rarely illustrated. Methods: We screened out the tRNA derivative, tRF-Val-CAC-016, based on the tsRNA sequencing and demonstrated the effect tRF-Val-CAC-016 exerted on GC proliferation in vitro and in vivo. We applied Dual-luciferase reporter assay, RIP assay, and bioinformatic analysis to discover the downstream target of tRF-Val-CAC-016. Then CACNA1d was selected, and the oncogenic characteristics were verified. Subsequently, we detected the possible regulation of the canonical MAPK signaling pathway to further explore the downstream mechanism of tRF-Val-CAC-016. Results: As a result, we found that tRF-Val-CAC-016 was low-expressed in GC, and upregulation of tRF-Val-CAC-016 could significantly suppress the proliferation of GC cell lines. Meanwhile, tRF-Val-CAC-016 regulated the canonical MAPK signaling pathway by targeting CACNA1d. Conclusions: tRF-Val-CAC-016 modulates the transduction of CACNA1d-mediated MAPK signaling pathways to suppress the proliferation of gastric carcinoma. This study discussed the function and mechanism of tRF-Val-CAC-016 in GC for the first time. The pioneering work has contributed to our present understanding of tRNA derivative, which might provide an alternative mean for the targeted therapy of GC.
Designing and Modeling of a Municipal Wastewater Treatment Plant With GPS-X
Authors: Sakib Fahim Shahriar
Published: January 2022

Wastewater treatment is the process used to remove contaminants from wastewater to produce an effluent suitable for discharge to the environment. Several kinds of wastewater are treated based on the concentration of various parameters. Domestic Wastewater/Municipal Wastewater is treated in Sewage Treatment Plants (STP), which involve various types of processes like physical, chemical and biological to treat the wastewater better. The treatment plant involves five steps of the process – preliminary treatment, primary treatment, secondary treatment, tertiary treatment and sludge treatment to meet the safe disposal guidelines of the department of the environment. In this paper, a municipal wastewater treatment plant for Uttara City is designed and modeled with GPS-X. GPS-X is a wastewater treatment plant modeling software package that is used for verify the treatment process. The design calculation of all unit operations is shown with a specification table. The Process Flow Diagram (PFD), Process Block Diagram (PBD) and mass balance of the process are expressed in the article. The design calculation of the STP is performed with a steady-state process. After each unit operation, the concentration of various parameters – TSS, BOD, VSS, TN is analyzed and the removal efficiency for different equipment is calculated. The STP is designed to maintain the guidelines of the Department of Environment, Bangladesh. At the end of the paper, the designing and modeling steps of a sewage treatment plant will be pursued. Finally, some recommendations are done in the conclusion section.
Lung Stereotactic Radiation Therapy: Intercomparison of Several Irradiation Devices in Terms of Outcome and Predictive Factors
Authors: Reun Eymeric Le , Casutt Alessio , Durham André , Bouchaab Hasna , Romano Edouard , Lovis Alban , Krueger Thorsten , Von Garnier Christophe , Ozsahin Esat-Mahmut , Kinj Rémy
Published: January 2022

Background: Stereotactic body radiotherapy (SBRT) is recommended for the treatment of inoperable early stage non-small-cell lung cancer and lung oligometastases. The radiation oncology department of the Lausanne University Hospital (CHUV) gathers three different radiotherapy devices able to treat pulmonary lesions in SBRT conditions: CyberKnife® (CK), Helical Tomotherapy® (HT), and volumetric modulated arc therapy (VMAT). The aim of this study is to define the patients’ outcome in terms of irradiation efficacy and toxicities after lung SBRT depending of the choice of the SBRT technique.Methods: We retrospectively analyzed the clinical, radiological, and dosimetric data of patients with primary lung tumor or pulmonary oligometastases treated with SBRT between January 2016 and February 2020. We analyzed descriptive data using the Chi-2 test for proportions and the T-test for means comparisons, survival data by the Kaplan-Meier method and comparisons between groups by the Log-rank test and Cox-regression.Results: We identified 111 patients mostly in good condition (82.9% PS 0-1) with a median age of 71.4 years. One hundred forty-two lesions were treated with a typical fractionation of 55 Gy in 5 fractions, delivered by CK (59.9%), VMAT (38.0%), or HT (2.1%). Compared to other techniques, CK technique allowed to treat comparable gross tumor volume (GTV; 2.1 vs 1.4cc, p = 0.84) with smaller planning treatment volume (PTV; 12.3 vs 21.9 cc, p = 0.013), and was associated with a lower mean lung dose (MLD; 2.6 vs 4.1 Gy, p < 0.001), a lower V5 (13.5 vs 19.9 cc, p = 0.002) and a lower V20 (2.3 vs 5.4 cc, p < 0.001). Local control rates at 2 years were not different depending on the irradiation device, respectively of 96.2% (range, 90.8-100) and 98.1% (range, 94.4-100), p = 0.68. Toxicity incidence was significantly increased with V5 value > 17.2% (56.0 vs 77.4%, p = 0.021). Conclusions: Compared to other SBRT techniques, CK treatments permitted to treat comparable GTV with reduced PTV, MLD, V20, and V5. The dosimetric benefit of CK SBRT was not associated with a clear clinical benefit, with comparable outcome in terms of control rates and toxicity. Toxicity incidence was less frequent when reducing the V5. The use of CK is particularly attractive in case of multiple courses of lung SBRT or in case of local relapse requiring lung re-irradiation.Trial registration: Registered on February 24th 2021, ID 2021-00267, with the authorization of the CER-VD ethics committee (Switzerland).
Study on Hydrogenation Performance of Oil-Soluble Molybdenum Catalyst in Coal-Oil Co-Processing
Authors: Wang Guangyao , Wang Xiqian , Zhao Yuan
Published: January 2022

An oil-soluble molybdenum catalyst was synthesized by a simple and novel method and studied for hydrogenation in coal-oil co-processing. The catalyst was characterized by infrared spectrum (IR), thermogravimetry (TG), X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). The morphology and crystal structure of catalyst was characterized with scanning electron microscope (SEM) and high resolution transmission electron microscopy (HRTEM). The catalyst can be considered as a precursor that can be converted into active MoS2 components through thermal decomposition and sulfidation. The hydrogenation experiment was carried out by the model reactants of tetradecane and 2-methylnaphthalene with a change of reaction (405℃-445℃) temperature and concentrations of molybdenum catalyst (Mo conc. 0.6-10 mg/g), and results showed that the delightly hydrogenation function of catalyst is to improve the saturation of aromatic ring. The most abundant stacking numbers of decomposed catalyst were 2 and 3, accounting for 53% of all catalyst microcrystalline units. The rapid hydrogenation stage and the significant decrease of feed heavy fraction in co-processing experiment provided the evidence that the hydrogenation performance of the synthesized catalyst is remarkable in coal-oil co-processing.
Are People with Poor Differentiation of Self at Risk of Developing Eating Disorders? A Study of Jewish and Arab Participants
Authors: Peleg Ora , Tzischinsky Orna
Published: January 2022

Purpose: In light of findings that Israeli Arabs report higher prevalence of eating disorders (EDs) than Israeli Jews and that higher rates of the risk of EDs have been reported by females than males, the first aim of this study was to further investigate the cultural and gender differences in differentiation of self (DoS) and risk of developing EDs among Israeli young adults. The second aim was to examine whether DoS is associated with the risk of EDs. Methods: Of the 859 participants (670 females, mean age 26.8), 440 were Jewish and 419 were Arab. Participants took the Eating Attitudes Test (EAT-26) and completed the Differentiation of Self-Revised (DSI-R) questionnaire.Results: Results revealed that Jewish participants had significantly lower diet, bulimia, and total EAT-26 scores than their Arab counterparts, while Jewish female participants had higher dieting and lower emotional cutoff scores than Jewish male participants. In addition, Jews who reported higher levels of risk of EDs showed higher levels of BMI, emotional reactivity, emotional cutoff, and fusion with others. Arabs who reported higher levels of risk of EDs reported higher levels of BMI and emotional cutoff and lower levels of I-position. Conclusion: People with high risk of EDs may have difficulty maintaining intimate family relationships. In distressing situations, they tend to disconnect rather than share with or gain support from significant others. In each culture, the risk of EDs increases for differently: among the Arab participants, when feelings and needs remain unexpressed; among the Jewish participants, even when they have symbiotic family relationships.Level of evidence: Level V, cross-sectional descriptive study
Evaluation of the Efficacy and Threshold of Serum Anti-mullerian Hormone (AMH) Levels for Diagnosis and Prediction of Polycystic Ovary Syndrome (PCOS) Among Indian Women.
Authors: Sumji Sajad , Bhat Abid , Rashid Aafia , wani Imtiyaz , Vasudevan Vishnu , Sehar Tajali , Ganie Mohd Ashraf
Published: January 2022

Purpose: PCOS women exhibit higher levels of AMH and has been proposed to add value to diagnosis of PCOS incase ambiguity. However, variable cutoffs of AHM for PCOS prediction have been reported. This study was designed to determine diagnostic threshold of serum AMH levels and its correlation with clinical, hormonal and ultrasonographic parameters among women with PCOS.Materials: In this prospective study, 113 women with PCOS as per Rotterdam criteria 2003 and 75 normo-ovulatory women were included. Clinical, biochemical, hormonal and sonographic assessment in addition to serum AMH levels were determined using standard methodology.Results: Mean age was comparable (23.43±3.42vs.24.21±3.18 years) between cases and controls. The mean number of menstrual cycles per year were lower while as mean BMI, FG score, and serum testosterone were higher in cases than controls (p<0.05). The mean serum AMH level was significantly higher in PCOS group (7.84±3.67vs. 3.23 ±1.56 ng/mL) than controls. The serum AMH levels showed a positive correlation(p<0.05) with LH/FSH ratio (r = 0.206, p = 0.029), number of ovarian follicles(r=0.461) and volume,(r=0.521), but no correlation significant with age and BMI. As per receiver operating characteristic (ROC) curve, cut-off was worked out to be 3.76 ng/mL with 86.7% sensitivity and 62.7% specificity. Conclusion: Serum AMH levels correlate positively with PCOM among PCOS women and may be a potent diagnostic marker of ovarian dysfunction either alone or in conjunction with other tools to ensure timely diagnosis and early treatment of the disorder.
Plant Growth-Promoting Bacteria Associated with the Nests of the Seed-Harvester Ant, Trichomyrmex Scabriceps
Authors: Kumari Pooja , Rastogi Neelkamal , Singh Harikesh Bahadur , Rajput Rahul Singh
Published: January 2022

Colonies of seed harvester ants are commonly found in semiarid and arid areas of the world and have been studied for their seed dispersal behaviour. The present study focused on the bacteria associated with the nests of the harvester ant, Trichomyrmex scabriceps, and reveals that ant colonies link the aboveground resources with the belowground microbial communities as they accumulate organic debris in the close vicinity of their nests via their ecosystem engineering activities. Soil samples were collected from the nest chambers and the external debris piles of T. scabriceps colonies, located in managed ecosystems. The nest soil-associated bacteria were examined for their plant growth-promoting abilities via biochemical assays including phosphate solubilization, Indole acetic acid production, siderophore production and physiological assays including biocontrol potential against the soil pathogen, Sclerotium rolfsii. More than 60% of bacteria isolated from the ant nest-associated soil displayed plant-growth promoting ability. Bacillus sp., Azotobacter sp., Klebsiella sp., Comamonas sp., Tsukamurella sp., and Pseudoxanthomonax sp., demonstrated significantly high levels of gnotobiotic growth of the treated chickpea plants. The activities of phenylalanine ammonia-lyase and peroxidase enzymes were higher in plant growth-promoting bacteria treated and pathogen inoculated plants as compared to the control plants lacking the bacteria. Since T. scabriceps colonies often make their nests in the compact soil of unpaved paths of agroecosystems and gardens, these bacteria can act as highly effective biofertilizers and promote growth of the cultivated plants by increasing soil fertility and disease resistance attributes of the plant.
Effect of Intake Manifold Geometry on Cylinder-to-Cylinder Variation and Tumble Enhancement in Gasoline Direct Injection Engine
Authors: Shin Jisoo , Kim Donghwan , Son Yousang , Park Sungwook
Published: January 2022

In order to improve the performance of the gasoline direct injection engine system, it is fundamentally important to reduce the cylinder-to-cylinder variation which affected by the intake manifold geometry. Furthermore, the early tumble development which influences the characteristics of the mixture as followed by the atomization and evaporation of the fuel, also greatly affects engine performance. Thus, in this study, the cylinder-to-cylinder variation in volumetric efficiency and tumble for two different type of intake manifold (curved type and straight type) was investigated using computational fluid dynamic program, CONVERE v2.4. And influence of the intake manifold curve radius to the early flow intensity and tumble development was analyzed. As a result, it was advantageous for cylinder-to-cylinder variation in the straight intake manifold compared to the curved intake manifold. When the intake manifold curve radius was increased in the straight intake manifold, it was effective in strengthening the early flow and tumble intensity. At 3000 rpm, the distance from the intake manifold inlet to the port also had an effect. Therefore, it is possible to improve the intake manifold performance by increasing the intake manifold curve radius and adapting turbocharging at engine speeds above 3000 rpm.
A Study on the Correlation Between M2 Macrophages and Regulatory T Cells in the Progression of Colorectal Cancer
Authors: Chen Yanlei , Gao Yu , Ma Xueqian , Wang Yanping , Liu Jinhao , Yang Chunyu , Bao Cuifen , Song Xiaoyu , Feng Yang , Sun Yan , Qiao Shifeng
Published: January 2022

Background: M2 macrophages and regulatory T cells (Tregs) can promote tumors and development by inhibiting the anti-tumor immune response. This study investigated the number of CD163‐positive M2 macrophages and Foxp3-positive Tregs in the progression of colorectal cancer. It also investigated the correlation and of M2 macrophages and Tregs.Methods: Postoperative tissue specimens and clinical data were collected from 197 patients with colorectal cancer who underwent initial surgical treatment in The Second Ward of Colorectal Surgery of the First Affiliated Hospital of Jinzhou Medical University from March 2020 to December 2020. Use immunohistochemical methods to detect the expression levels of CD163 protein-labeled M2 macrophages and Foxp3 protein-labeled Tregs in colorectal cancer tissues, matched paracancer tissues and lymph node tissues. Analyze the correlation between CD163 and Foxp3 in cancer tissues and lymph node tissues, as well as the relationship between clinicopathological characteristics and preoperative tumor markers. Results: M2 macrophages and Tregs were significantly positively correlated in cancer and lymph node tissues, which significantly increased in cancer and metastatic lymph node tissues. Interestingly, M2 macrophages in non-metastatic lymph nodes also increased significantly in patients with metastatic lymph nodes. Tregs stage I+II is higher than stage III+IV in paraneoplastic tissues. In addition, both CD163 and Foxp3 were upregulated with increasing tumor TNM stage, depth of infiltration, lymphatic metastasis, and depth of infiltration, and both were positively correlated with CEA. Conclusion: M2 macrophages and Tregs are important indicators of colorectal cancer progression and lymph node metastasis. There is a certain correlation between the two types of cells. It is possible that M2 macrophages, together with suppressor cells Tregs, promote an immunosuppressive environment.
Attempt TCP ACK-Storm Based Virtual Network Attacks and Defence Solutions
Authors: Khanh Tran Namm , Thanh Ta Minh
Published: January 2022

The rapid development of the digital age has been pushing people to access a mobile working environment when handsets are becoming more diverse and convenient with the help of Virtualization Technology. The speed and usability of Virtualization Technology are astounding for saving initial investment costs and optimizing IT infrastructure. Such Virtualization Technology is what businesses are interested in and makes the virtual server market growing strongly, especially for businesses that have many branches. However, virtual systems (hypervisors) are more vulnerable than traditional servers according due to many network attacks from curious users. Therefore, it's necessary to prepare for the worst circumstances, understand clearly, and research for new threats that can break down the virtual system. In this paper, we attempt to demonstrate the TCP ACK storm based DoS (Denial of Service) attack on virtual and Docker networks to show the threats that easily are happen on services deploying on virtual networks. Based on such consequence, we propose some solutions to prevent our virtual system from potential risks.
The Effect of Co-dependent (Thinking in Motion [tim]) Versus Single-modality (Cognifit) Interventions on Cognition and Gait Among Community Dwelling Older Adults With Cognitive Decline: a Randomized Controlled Study
Authors: Embon-Magal Shiri , Krasovsky Tal , Doron Israel , Asraf Kfir , Haimov Iris , Gil Efrat , Agmon Maayan
Published: January 2022

Background. Cognition and motor skills are interrelated throughout the aging process and often show simultaneous deterioration among older adults with cognitive decline. Co-dependent training has the potential to ameliorate both domains; however, its effect on the gait and cognition of older adults with cognitive decline has yet to be explored. The aim of this study is to compare the effects of the well-established single-modality cognitive computerized training program, CogniFit, with “Thinking in motion (TIM),” a co-dependent group intervention, among community-dwelling older adults with cognitive decline. Methods. Employing a single-blind randomized control trial design, 47 community-dwelling older adults with cognitive decline were randomly assigned to eight-week thrice weekly trainings of TIM or CogniFit. Pre- and post-intervention assessments included cognitive performance, evaluated by a CogniFit battery, as a primary outcome, and gait, under single- and dual-task conditions, as a secondary outcome. Results. CogniFit total Z scores significantly improved from baseline to post-intervention for both groups. There was a significant main effect for time [F (1, 44) = 17.43, p<.001, ηp2=.283] but not for group [F (1, 44) = 0.001, p=.970]. No time X group interaction [F (1, 44) = 1.29, p=.261] was found. No changes in gait performance under single and dual-task performance were observed in both groups. Conclusions. The findings show that single-modality (CogniFit) and co-dependent (TIM) trainings improve cognition but not gait in older adults with cognitive decline. Such investigations should be extended to include various populations and a broader set of outcome measurements. Trial registration: anzctr Id: 371522. Date: 08/11/2016
Tomodensitometric Bone Anatomy of The Intervertebral Foramen of The Lower Cervical Spine: Measurements and Comparison of Foraminal Volume in Healthy Individuals and Patients Suffering from Cervicobrachial Neuralgia Due to Foraminal Stenosis.
Authors: COUDERT Pierre , LAINE Gaetan , POINTILLART Vincent , DAMADE Camille , BOISSIERE Louis , VITAL Jean-Marc , BOUYER Benjamin , GILLE Olivier
Published: January 2022

Purpose

Degenerative foraminal stenosis of the cervical spine can lead to cervicobrachial neuralgias. Computed tomography (CT)-scan assists in the diagnosis and evaluation of foraminal stenosis. The main objective of this study is to determine the bony dimensions of the cervical intervertebral foramen and to identify which foraminal measurements are most affected by degenerative disorders of the cervical spine. These data could be applied to the surgical treatment of this pathology, helping surgeons to focus on specific areas during decompression procedures.
Methods

A descriptive study was conducted between two groups: an asymptomatic one (young people with no evidence of degenerative cervical spine disorders) and a symptomatic one (experiencing cervicobrachial neuralgia due to degenerative foraminal stenosis). Using CT scans, we determined a method allowing measurements of the following foraminal dimensions: foraminal height (FH), foraminal length (FL), foraminal width in its lateral part ((UWPP, MWPP and IWPP (respectively Upper, Medial and Inferior Width of Pedicle Part)) and medial part (UWMP, MWMP and IWMP (respectively Upper, Medial and Inferior Width of Medial Part)), and disk height (DH). Foraminal volume (FV) was calculated considering the above data. Mean volumes were measured in the asymptomatic group and compared to the values obtained in the symptomatic group.
Results

Both groups were made up of 10 patients, and a total of 50 intervertebral discs (100 intervertebral foramina) were analyzed in each group. Comparison of C4C5, C5C6 and C6C7 levels between both groups showed several significant decreases in foraminal dimensions (p< 0,05) as well as in foraminal volume (p <0.001) in the symptomatic group. The most affected dimensions were UWPP, MWPP, UWMP, MWMP and FV. The most stenotic foraminal areas were the top of the uncus and the posterior edge of the lower plate of the overlying vertebra.
Conclusion

Using a new protocol for measuring foraminal volume, the present study refines the current knowledge of the normal and pathological anatomy of the lower cervical spine and allows us to understand the foraminal sites most affected by degenerative stenosis. Those findings can be applied to foraminal stenosis surgeries. According to our results, decompression of the foramen in regard of both uncus osteophytic spurs and inferior plate of the overlying vertebra might be an important step for nerve roots release.
Interphase misorientation as a tool to study metamorphic reactions and crystallization in geological materials
Authors: Morales Luiz F.G.
Published: January 2022

Interphase boundaries are planar defects that separate two different minerals, which in general have different compositions and/or crystalline structures; they may play an important role as a pathway for fluids in rocks and affect their physical properties. To completely characterize interphase boundaries, one needs to define the misorientation between adjacent grains and the orientation of the grain boundary plane. The analysis performed here is limited to the misorientation characterization and the trace of the interphase boundary. Although the determination of possible orientation relationships between the two adjacent phases is routinely performed by selected-area electron diffraction in a transmission electron microscope, this method lacks statistical representativeness. With the advent of techniques like electron backscatter diffraction (EBSD), it is possible to calculate orientation relationships not only in single pairs of crystals of the same phase but in full thin sections and between different minerals. The interphase misorientation is calculated from two orientations of two adjacent crystals of different phases. A set of single misorientations is then used to calculate the misorientation distribution function (MDF), from where it is possible to identify a maximum and its crystallographic interpretation. If we then know the misorientation and the unit-cell parameters of the individual phases, the crystal-lographic relationships between the different phases can be described with the pairs of parallel crystal-lographic planes and the pairs of crystallographic directions. In this paper, I present examples of the use of interphase misorientation analysis on the transformation of calcite-aragonite, olivine-antigorite, magnetite-hematite, and on the study of orientation relationships between plagioclase-olivine-ilmenite in mid-ocean ridges gabbros (ODP Hole 735).