bluuebunny/crossref_metadata_2025 huggingface dataset:
H Syndrome with Atypical Presentation – A Diagnostic Enigma
Authors: Aithal Sowmya S. , Sakkaravarthi Vinupriya , Gopalakrishnan K. , Chakravarthy Anitha
Published: July 2024

H syndrome is a rare autosomal recessive genodermatosis characterized by cutaneous manifestations and other systemic involvement. It presents with features like hyperpigmentation, hypertrichosis, hepatosplenomegaly, hearing loss, hallux valgus, hyperglycemia, low height, hypogonadism, and heart anomalies. Without a high index of suspicion, it is often misdiagnosed with other sclerodermatous cutaneous disorders. This case report highlights the clinical variability of H syndrome. An 8-year-old female child presented with hyperpigmented, hypertrichotic indurated patches with hyperglycemia and short stature. Histopathology showed dense lymphohistiocytic infiltrate and fibrosis in the dermis and subcutaneous tissue. The patient lacked features like heart anomalies, hearing loss, and hallux valgus, suggesting forme fruste presentation of H syndrome. An overlap between features of H syndrome and PHID syndrome is also suspected because of atypical presentation.
Cutaneous Manifestations of Diabetes Mellitus in a Tertiary Care Hospital in Eastern India: A Cross-sectional Study
Authors: Barman Srutee , Achar Arun , Sengupta Nilanjan , Chowdhury Joyeeta , Bhakta Abhijit
Published: July 2024

Background:

Diabetes mellitus is a chronic metabolic disorder and is a major public health problem worldwide. Skin diseases can appear as the first sign of diabetes or can develop at any time in the course of the illness.

Purpose:

This study aimed to determine the pattern and prevalence of skin manifestations in patients with diabetes mellitus.

Methods:

An observational cross-sectional study was done on 80 Type 1 and Type 2 diagnosed diabetes mellitus patients and with informed consent, they were thoroughly examined for their respective skin disorders.

Results:

Among 80 patients, 35% of patients had infectious skin lesions, whereas 20% had noninfectious dermatosis only. More than one type of dermatosis was seen in 45% of patients. Candidal balanoposthitis was the most common fungal infection.

Limitation:

Limited sample in a single center.

Conclusion:

Infections were more prevalent compared to noninfectious disease in a population with uncontrolled diabetes mellitus. Pruritus was the most common disorder among the other diabetic complications.
Surgical Approach of Pleomorphic Dermal Sarcoma on the Scalp: A Case Report
Authors: Munayco Maldonado Gloria M. , Meaden Ross M. , Kaminsky Alexander J.
Published: July 2024

Pleomorphic dermal sarcoma (PDS) is a fast-growing mesenchymal tissue tumor with similar characteristics to an atypical fibroxanthoma (AFX) presenting a significant clinical challenge to diagnose for physicians. We report a 79-year-old male presenting with a 3-month history of a lesion on his scalp that had been previously superficially biopsied yielding a diagnosis of PDS or AFX. Following a second biopsy, new findings led to the diagnosis of PDS. A wide local excision with 2 cm margin with delayed split-thickness skin graft reconstruction was performed. Treatment for PDS favors wide local excision with a 2–3 cm margin and adjuvant radiotherapy if perineural involvement. We support the following recommendations: full-thickness appropriate tissue diagnosis, pulmonary computed tomography scan, or X-ray to rule out metastasis, followed by a multidisciplinary team evaluation. These complex cases should be presented at a tumor board and tailored treatments should be based on patient risk factors and relevant history.
Evaluation of child’s behavior during the pit and fissure sealant administration using the rubber dam and MiniDam: A randomized clinical trial
Authors: Rahul Shaik , Saikiran Kanamarlapudi Venkata , Elicherla Niharika Reddy , Anchala Karthik , Singaraju Anuja , Nuvvula Sivakumar
Published: July 2024

Background:

Dental caries is a multifactorial disease that manifests itself in primary and permanent dentitions. Pit and fissure sealants have become the most effective noninvasive treatment for addressing teeth with deep pits and fissures in children. The purpose of the present study was to evaluate the behavior of the child when administering the pit and fissure sealant using the rubber dam and MiniDam.

Methodology:

Fifty-two children in the age range of 9–12 years were randomly allocated into two groups: Group I, rubber dam and Group II, MiniDam. The children were randomly assigned into two groups with 26 members in Group 1 (rubber dam isolation) and 26 members in Group 2 (MiniDam isolation). Children’s anxiety was assessed using the modified Venham scale and heart rate. The children’s pain intensity was assessed using Memojis Pain Scale. The data collected were tabulated and statistically analyzed using SPSS software. The level of significance was established at 0.05.

Results:

Intergroup comparison of heart rates showed a statistically significant difference for both the groups at various intervals (P value 0.05), that is, before placing the dam, with the dam, and during treatment. Pain and anxiety scores showed a statistically significant difference in both the groups before and after the procedure (P < 0.05).

Conclusions:

The use of MiniDam can offer a better option for the pit/fissure sealant procedure due to its unique qualities, including simplicity of placement, improved behavior management, and less chair time in children.
Caries assessment and salivary microbial analysis in patients diagnosed with mucopolysaccharidosis
Authors: Anju Vinod , Raj N. Sunil
Published: July 2024

Background and Objectives:

Mucopolysaccharidosis (MPS) is a group of lysosomal storage disorders that cause the deposition of polysaccharides in cells. This causes systemic and oral manifestations, which can be observed clinically and radiographically. The present study aimed to assess dental caries, the effect of salivary pH, and the change of microflora on teeth in patients diagnosed with MPS.

Materials and Methods:

The study included children affected with mucopolysaccharidosis (n = 50) and healthy children (n = 50) in the control group between 3 and 15 years of age. The pH of saliva and decayed, missing, and filled teeth/decayed extracted and filled teeth index were noted and recorded. For the microbial analysis, saliva was inoculated into blood agar, MacConkey agar, Candida CHROMagar, and Mitis Salivarius agar, then inspected for colony-forming units, which were counted and recorded based on the colony characteristics and gram staining.

Statistical Analysis:

Intergroup comparison of the test parameters was done using the Mann–Whitney test. P < 0.05 was considered statistically significant.

Results:

The results showed significantly higher total microbial load (P = 0.00008), streptococcus viridans species (P = 0.00001), and Candida species (P = 0.0038) in the study group. The caries incidence was also higher in the study group for both primary (P = 0.0096) and permanent dentition (P = 0.0251), and salivary pH was more acidic (P = 0.00001) in the patients diagnosed with MPS.

Interpretation and Conclusion:

Patients diagnosed with MPS have a higher microbial load, more acidic saliva, and subsequently, a higher caries incidence than normal healthy children. Hence, regular dental evaluation, prevention, and treatment must be integrated into their health-care regimen.
Interexaminer agreement among pediatric dental specialists in assessment of tonsil size, Friedman tongue position, and Friedman staging of obstructive sleep apnea in children: An observational study
Authors: Nair Lekshmy S. R. , George Sageena , Anandaraj S. , Anuja S. , Naveena T. V. , Aishwarya U.
Published: July 2024

Background:

The evaluation of tonsil size, Friedman Tongue Position (FTP), and Friedman staging in pediatric obstructive sleep apnea (OSA) holds significant clinical importance, offering manifold advantages in diagnosis and surgical management.

Aims and Objectives:

This study aimed to assess the reliability of pediatric OSA evaluation by determining inter-examiner agreement among pediatric dental specialists.

Materials and Methods:

Conducted at the Department of Pediatric Dentistry, PMS College of Dental Science and Research Hospital (2023-2024), this observational study utilized conventional consulting rooms, headlights, and examination chairs. Thirteen medical practitioners reviewed video recordings of the oropharyngeal regions of twelve pediatric patients exhibiting mouth breathing. Friedman staging was determined based on tonsil size and tongue position gradings.Inter-examiner agreement was evaluated using Fleiss kappa analysis.

Results:

Observers, including residents and practitioners in pediatric dentistry, demonstrated poor agreement regarding FTP and tonsil grading.

Conclusion:

Understanding the nuances of tonsil size and FTP in pediatric OSA evaluation, along with identifying avenues for refinement, can enhance medical decision-making among healthcare providers, including pediatric dentists.
Tuberculosis diagnostic practices among private medical practitioners of modern medicine in South India – A cross-sectional study
Authors: Naidu Navya Krishna , Kondagunta Nagaraj , Guthi Visweswara Rao
Published: July 2024

Background:

India has the highest tuberculosis (TB) burden in the world and account for nearly one-fourth of the global burden of TB. Although the Indian government provides a basic national health service, an increasingly large number of health-care interactions in India are with the physicians in the private sector.

Objective:

The objective is to study the TB diagnostic practices among private medical practitioners and to determine the association of diagnostic practices with socio-demographic factors, the Revised National Tuberculosis Control Programme (RNTCP) training status, and professional/academic qualification of private medical practitioners.

Materials and Methods:

The current study was a cross-sectional study conducted in the urban areas of Nalgonda district between October 2015 and September 2017. The study included all medical general practitioners (GP) and all specialists practicing internal medicine, chest medicine, and pediatrics, registered with the Indian Medical Association (IMA) branches and had a private practice in the study area. The study included 101 private medical practitioners from three IMA branches. The data on diagnostic practices of TB and RNTCP training status were collected by an interview using a pretested semi-structured questionnaire. The data analysis was done using Statistical Package for Social Sciences (SPSS) 19th version.

Results:

The majority of study participants in this study were GP, while specialists constituted a smaller portion. Most of these private medical practitioners opted sputum smear examination as their second preferred investigation after a chest X-ray. For the diagnosis of pulmonary TB, majority of the private practitioners preferred both sputum smears examination and chest X-ray. The private medical practitioners who had received the RNTCP training were employing sputum smear microscopy as a diagnostic tool and were also aware about notification of TB.

Conclusions:

Overreliance on chest X-ray as the investigation of choice to diagnose pulmonary TB and for follow-up. Training in RNTCP has a positive impact on practicing standard diagnostic practices, treatment, and referral practices on private medical practitioners.
Comparative study on the quality of electrocardiogram and arrhythmia detection using wireless ambulatory Vigo SmartHeart Holter and conventional Holter
Authors: Bala Sudha , Mirza Mehdi Ali , Mavoori Archana , Bandaru Rajiv Kumar , Kampally Mallikharjuna , Agarwal Sony , Chormalle Rishabh
Published: July 2024

Background:

Wireless Holter monitors can be a great alternative to the traditional wired holter monitoring potentially giving better patient outcomes. However, the technology is new and less explored for the quality of ECG wave forms.

Objective:

This study was taken up to compare the quality of electrocardiogram (ECG) and arrhythmia detection using a traditional Holter and a wireless ambulatory smart ECG – Vigo SmartHeart (VSH) that functions with a Mobile application.

Materials and Methods:

The present study was cross-sectional in nature. We enrolled the patients indicated for continuous ECG monitoring. All the enrolled patients were connected to VSH wireless Holter solution and a conventional Holter monitor simultaneously. The ECGs generated were compared through descriptive statistics such as mean, standard deviation, and correlation by Pearson’s correlation method.

Results:

Seventy-one patients had simultaneous ECG recordings by both systems. The Pearson correlation for P wave, QRS, PR, QT, and ST was measured as 0.93, 0.93, 0.99, 0.36, and 0.98, respectively. The minimum heart rate (HR), maximum HR, RR interval, P wave, QRS complex, PR, and ST segments showed a statistically significant correlation between Smart Heart and Conventional Holter. 17 ECG events were reported, of which 14 were detected by both. The events missed by conventional Holter and detected by VSH were Atrioventricular block (2), Supraventricular tachycardia (1), and Intraventricular conduction delay (1).

Conclusions:

The quality of the report generated by both the methods was comparable to ECG wave quality, However, arrhythmia was picked up by the SmartHeart with better precision compared to conventional Holter. Thus, VSH can serve as a viable and potential alternative tool to screen and help in reducing the morbidity and mortality related to arrhythmias.
Acute dacryocystitis secondary to Burkholderia cepacia and Sphingomonas paucimobilis mixed infection: A novel case report
Authors: Alsobaie Nasser , Alotaibi Humoud , Madani Firas , Sirajuddin Fatima , Althaqib Rawan
Published: July 2024

Acute dacryocystitis caused by Burkholderia Cepacia and Sphingomonas Paucimobilis is uncommon. To the best of our knowledge, presence of mixed pathogens Burkholderia Cepacia and Sphingomonas Paucimobilis causing acute dacryocystitis in immunocompetent patients never been described. Burkholderia Cepacia and Sphingomonas Paucimobilis been reported only as a single microorganism causing other ocular infections in immunocompromised patients. Middle age, medically free female patient, presented to the emergency department at our hospital, with a history of nasolacrimal duct obstruct (NLDO) complaining of inferior preocular swelling associated with localized pain diagnosed as acute dacryocystitis. She was on oral Amoxicillin/clavulanic acid, oral Nitroimidazole antimicrobial and topical Tobramycin from elsewhere. However, no improvement had been noticed. We kept the patient on the same medications and swaps taken for culture and sensitivity. Patient presented to the first follow-up appointment with no improvement on her status. Culture and sensitivity revealed 2 pathogens: Burkholderia Cepacia and Sphingomonas Paucimobilis. We have changed the antibiotic to oral Trimethoprim/ Sulfamethoxazole as it showed positive sensitivity to the pathogens based on the sensitivity chart. Second follow-up appointment patient’s condition improved.
Clinical characteristics of lean metabolic-associated fatty liver disease and the impact of concurrent diabetes mellitus
Authors: Cheng Yu-Ming , Wang Shao-Wen , Wang Chia-Chi , Kao Jia-Horng
Published: July 2024

ABSTRACT

Objectives:

Metabolic-associated fatty liver disease (MAFLD) was proposed in 2020 to replace the original term nonalcoholic fatty liver disease (NAFLD) with new diagnostic criteria. The disease risks of lean and overweight/obese MAFLD patients remain controversial.

Materials and Methods:

The participants from the Taiwan biobank cohort were included. Advanced liver fibrosis is defined as NAFLD fibrosis score (NFS) >0.675. We use carotid plaques of duplex ultrasounds to diagnose atherosclerosis.

Results:

A total of 20,058 participants (age 55.67 ± 10.32; males 37.6%) were included in the final analysis. Seven thousand eight hundred and forty-three (39.1%) participants were diagnosed with MAFLD. Of them, 965 (12.3%) were lean MAFLD patients. Among lean MAFLD patients, 25.6% were comorbid with diabetes mellitus (DM). Lean MAFLD patients were older and had higher percentages of females and DM than overweight/obese MAFLD patients. After propensity score matching for age and sex, they had lower levels of NFS but a higher percentage of carotid plaques. Among four subtypes of MAFLD including “lean with DM,” “lean without DM,” “overweight/obese with DM,” and “overweight/obese without DM,” logistic regression showed that “lean with DM” subjects had the highest risk of atherosclerosis and “overweight/obese with DM” subjects had the highest risk of advanced liver fibrosis in MAFLD patients.

Conclusion:

The population-based study revealed that lean MAFLD patients make up 12.3% of all MAFLD patients, and they have a higher proportion of coexisting diabetes. Among lean MAFLD patients concurrent with diabetes, they have the highest risk of atherosclerosis and should receive special attention clinically.
Advancements in minimally invasive surgery for adolescent idiopathic scoliosis: A case series and literature review
Authors: Ho Yi-Jen , Chiang Wen-Chun , Lin Ying-Chao
Published: July 2024

ABSTRACT

Objectives:

Minimally invasive surgery (MIS) has emerged as a promising alternative to conventional open techniques in the management of adolescent idiopathic scoliosis (AIS).

Materials and Methods:

This study presents a case series of six patients who underwent MIS for AIS at a spine center, employing a synergistic blend of intraoperative fluoroscopy, cone-beam computed tomography scans, and three-dimensional navigation technology. The surgical procedures were meticulously guided, with a focus on ensuring safety and precision in posterior pedicle fixation.

Results:

Our findings demonstrate substantial correction of spinal curvature postoperatively, with a mean Cobb’s angle reduction of 51.75%. In addition, MIS facilitated a mean estimated blood loss of 241.67 ml and a mean surgical duration of 391.33 min.

Conclusion:

Comparison with conventional open techniques reveals comparable or superior outcomes in terms of correction rates, patient recovery, and opioid usage. This study underscores the potential of MIS in achieving favorable clinical outcomes while minimizing surgical impact and advancing the treatment landscape for AIS.
Serum osteopontin level is independently associated with arterial stiffness in patients on hemodialysis
Authors: Huang Po-Yu , Hsu Bang-Gee , Wang Chih-Hsien , Tsai Jen-Pi
Published: July 2024

ABSTRACT

Objectives:

Carotid–femoral pulse wave velocity (cfPWV) is an approach primarily adopted to define arterial stiffness (AS), which is one of the major contributors to unfavorable cardiovascular outcomes. Osteopontin (OPN), in addition to regulation of bone homeostasis, is an inflammatory mediator of atherosclerosis. We performed a research which estimated the correlation between blood OPN levels and AS in participants on maintenance hemodialysis (MHD).

Materials and Methods:

One hundred and twenty-six patients who received long-term MHD were included in the cross-sectional study. cfPWV values were calculated based on the carotid and femoral pulsation waveforms. Patients with cfPWV >10 m/s were categorized into the AS group. We utilized a commercially available enzyme-linked immunosorbent assay to check serum concentrations of OPN.

Results:

Study patients belonging to AS were found to be older, had significantly higher prevalence of underlying diabetes mellitus (DM) and hypertension, had higher systolic blood pressure, and had higher serum total calcium and OPN levels. After adjusting for these variables, multivariate logistic regression analysis disclosed that OPN levels, older age, DM, and total serum calcium levels were independently correlated with AS in patients on MHD. Multivariate analysis based on forward stepwise linear regression also showed that the logarithmically transformed OPN level was an independent correlate of cfPWV in these participants.

Conclusion:

Serum OPN concentrations had a positive correlation with cfPWV and were therefore related to AS in patients on MHD.
Office-based pediatric urology procedures
Authors: Alwehaibi Abdulaziz , Alyami Fahad , Altwijri Faisal , Trbay Mahmoud
Published: July 2024

Introduction:

Office-based procedures under local anesthesia are not a popular and well-accepted concept in pediatric urology except for newborn circumcision. There is limited literature on the utilization of office-based procedures under local anesthesia in pediatric urology. In this study, we present our experience of office-based procedures under local anesthesia from a tertiary center.

Materials and Methods:

This is a retrospective study of the patients who underwent meatotomy and penile adhesion release in the clinic under local anesthesia between January 2017 and August 2022 by a single surgeon in a tertiary center. A total of 92 patients were included in this study.

Results:

There were 65 patients diagnosed with meatal stenosis and 27 patients diagnosed with penile adhesion. The overall incidence of recurrence was noted in four patients. Only one patient had minimal complications. The overall average follow-up was 5.39 months (1–10 months).

Conclusion:

Selective office-based procedure (meatotomy and penile adhesion release) under topical local anesthesia is a simple, safe, and effective method to treat such conditions with a high success rate, especially with financial and time constraints on health care nowadays.
Revolutionizing Cloud Resource Allocation: Harnessing Layer-Optimized Long Short-Term Memory for Energy-Efficient Predictive Resource Management
Authors: Sireesha Prathigadapa , S Vishnu Priyan , Govindarajan M , Rajan Sounder , Rajakumareswaran V
Published: July 2024

INTRODUCTION: This is the introductory text. Accurate data center resource projection will be challenging due to the dynamic and constantly changing workloads of multi-tenant co-hosted applications. Resource Management in the Cloud (RMC) becomes a significant research component. In the cloud's easy service option, users can choose to pay a fixed sum or based on the amount of time.
OBJECTIVES: The main goal of this study is systematic method for estimating future cloud resource requirements based on historical consumption. Resource distribution to users, who require a variety of resources, is one of cloud computing main objective in this study.
METHODS: This article suggests a Layer optimized based Long Short-Term Memory (LOLSTM) to estimate the resource requirements for upcoming time slots. This model also detects SLA violations when the QoS value exceeds the dynamic threshold value, and it then proposes the proper countermeasures based on the risk involved with the violation.
RESULTS: Results indicate that in terms of training and validation the accuracy is 97.6%, 95.9% respectively, RMSE and MAD shows error rate 0.127 and 0.107, The proposed method has a minimal training and validation loss at epoch 100 are 0.6092 and 0.5828, respectively. So, the suggested technique performed better than the current techniques.
CONCLUSION: In this work, the resource requirements for future time slots are predicted using LOLSTM technique. It regularizes the weights of the network and avoids overfitting. In addition, the proposed work also takes necessary actions if the SLA violation is recognized by the model. Overall, the proposed work in this study shows better performance compared to the existing methods.
Screening olfaction under dupilumab in chronic rhinosinusitis with nasal polyps
Authors: Mauthe T , Meerwein C M , Ryser F S , Brühlmann C , Yalamanoglu A , Steiner U C , Soyka M B
Published: July 2024

Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) frequently leads to olfactory dysfunction. This study aimed to assess the impact of dupilumab on CRSwNP patients, focusing on olfactory outcomes and potential correlations with other clinical factors. Methods: CRSwNP patients eligible for dupilumab therapy received subcutaneous Dupixent® injections every two weeks (300mg/2ml dupilumab). The 12-item Sniffin' Sticks Test (SST-12), fractional exhaled nitric oxide (FeNO) and Nasal Polyp Score (NPS) were assessed at baseline and after one, three, and six months. Patients also completed the Sino-Nasal Outcome Test (SNOT-22) weekly. Results: 26 CRSwNP patients were included. After one month, dupilumab led to substantial reductions in FeNO, SNOT scores, andNPS, whereas SST-12 scores improved significantly only after three months. A shift toward normosmia occurred, with 81% achieving normosmia after six months, and a drop in anosmia prevalence to 9.5%. Significant negative correlations between olfaction (SST-12) and polyp severity (NPS) at baseline and after six months were found, while no significant correlations were observed between SST-12 and FeNO or SNOT scores. Age did not correlate with olfaction. Conclusions: Dupilumab demonstrated efficacy in restoring olfaction in CRSwNP patients. Reaching normosmia in over 80% ofpatients after six months of treatment underscores the drug's effectiveness in managing this challenging symptom.
Joseph Conrad in the eyes of Kazimierz Wierzyński: Fearless of the Boundless and Familiar with the Infinite
Authors: Dudek Jolanta
Published: July 2024

Kazimierz Wierzyński (1894-1969) is now considered to be one of the greatest modern Polish poets. He was born in Drohobycz (which is now in western Ukraine) and studied literature and philosophy in Cracow and Vienna. During the interwar years he lived in Warsaw, after which for several years (1939-1941) he lived as a wartime refugee before spending more than twenty years in the United States. An émigré for the rest of his life, he finally settled in London, where he died in 1969. Wierzyński’s poetry – like the works of Joseph Conrad – exhibits a particular sensibility to nature (perceived as a living organism) and the outside world, which is full of extraordinary places, objects, people and phenomena that invite us to reflect on the deeper meaning of our existence as human beings. Both writers share a stoic response to adversity and a fidelity to conscience and to the heritage of European culture.

In his 1924 sketch entitled “Conrad’s Great Silence,” Wierzyński saw Conrad above all as a writer who yearns for the infinite, whose “maritime reflection is reproduced in his work.” Twelve years later, in a narrative poem entitled Lord Jim (forming part of his 1936 collection entitled Kurhany), Wierzyński brought the eponymous character of Conrad’s novel into the pantheon of the Polish collective imagination. The fate of Lord Jim, who is tormented by nostalgia for his native England (to which he cannot return) would seem to foreshadow that of the émigré poet whom Wierzyński himself was soon to become.

In the titular poem of Wierzyński’s wartime collection Róża wiatrów (The Wind Rose – 1942), Conrad appears as a “role model” for all Polish wartime refugees and émigrés, who, like castaways, search for their own guiding light “in the Conradian sky” – a light that could help them find a safe haven where they could live and work in their own artistic realm without the need to care about literary fashions. This poem has been translated into English (under the title The Compass Rose) by Mary Phelps (Kazimierz Wierzyński, Selected Poems, New York: Voyages Press, 1959). In the opinion of the author of the present article, this translation fails to correctly convey certain key images and allusions which enrich the meaning of the poem and which connect it with the poet’s own personal situation as an émigré writer.
Sensibilidad al cambio del Voice Handicap Index y su versión abreviada, adaptados al español rioplatense de Argentina (Índice de Desventaja Vocal)
Authors: Román-Zubeldia Juana
Published: July 2024

Aim. To evaluate the responsiveness of the “Índice de Desventaja Vocal” (Argentinian version of the Voice Handicap Index) consisting in 30 items (IDV-30) and its abbreviated version (IDV-10).
Methodology. The IDV-30 and IDV-10 were administered to subjects with dysphonia of various etiologies, both before (“PRE”) and after (“POST”) receiving voice therapy. Independent samples were used for each instrument (IDV-30 n = 81; IDV-10 n = 92). The responsiveness of each index and each subscale of the IDV-30 was evaluated using the Wilcoxon test and it was determined whether statistically significant differences existed in scores of different diagnostic groups using the Kruskal-Wallis test.
Results. Participants who completed the IDV-30 required an average of 8.44 therapy sessions while those who completed the IDV-10 required an average of 8.34 sessions. When comparing the “PRE” and “POST”-voice therapy scores of the total IDV-30, as well as each of its subscales and the IDV-10, the difference was statistically significant (p<0.001). There were no statistically significant differences in the score changes obtained by each diagnostic group across any of the indices.
Conclusions. The responsiveness of the IDV-30 and IDV-10 has been confirmed, as statistically significant improvement in scores was evidenced by participants in the study after receiving voice therapy.
An Experimental Study on Strength and Durability of Concrete by Partial Replacement of Coarse Aggregate with Steel Waste and Fine Aggregate with Copper Waste
Authors: Aravinth B  , Kathirvel T  , Mohammed Thalha A  , Jagadeesh R  , Mrs. K .Nithyapriya
Published: July 2024

Global warming and environmental destruction have become the major issue in recent years. Emission of greenhouse gases from industries has impact on climate change. Preventing the depletion of natural resources and enhancing the usage of waste materials has become a challenge to the scientist and engineers. A number of studies have been conducted concerning the protection of natural resources, prevention of environmental pollution and contribution to the economy by using this waste material. The major byproducts of industry are slag. To solve the problem in effective manner slag is use in concrete by replacing natural coarse aggregate. In this study, the replacement was done with coarse aggregate by steel waste and copper for a M20 grade of concrete is used for a water cement ratio of 0.40.Tests on compressive strength at 7 days and14 days are conducted on specimens. The optimum strength is obtained on 30% replacement of coarse aggregate and fine aggregate by steel waste and copper waste. All mechanical properties were enhanced with the use of copper slag. Copper slag improved the resistance against chloride penetration. 40% copper slag partial replacement enhanced the properties of self-compacting concrete, and up to 60% of fine aggregate can be substituted with industrial copper waste. By this investigation, copper slag can be used as a sustainable building material.
Blockchain Technology: Features, Characteristics with a focus on its Types
Authors: B.Saritha
Published: July 2024

Blockchain Technology is the emerging component of IT and Computing and is a kind of encrypted record of data works on distributed database. This is furthermore dealt with the data related to the transaction, contract, independent record, etc. Digital ledger is important and also applicable in various platforms, not bounded in a particular place; and required in financial activities and services and hence it is worthy in healthy digital currency and transactions. Financial transaction is not associated with the third party and it keeps the data encryption and here participants no need to share personal data and thus Blockchain Technology is associated with the data breach. Insignificantly Blockchain not only reduces the data breach but also supports the multiple numbers of shared copies and it works on the same database. It helps in wage a data breach attack. Earlier it was known as Blockchain but gradually it is treated as a Technology and considered as important in Information Technology and impacting the financial sector rapidly. Blockchain Technology is required in various tangible and intangible asset management and required in tracking including recorded effectively within a network and ledger. Blockchain is therefore is a tool, a technique, as well as a procedure for sophisticated financial management. This paper is based on existing literature emphasizing Blockchain Technology with features, characteristics with a focus on its types.
A Comparative Study Of MVC Architecture Model Of Open Source Server Side Scripting Language Jsp And Php For Client-Server Architecture Based Applications Development
Authors: Vatsya Tiwari  , Manoj Varshney  , Kishan Pal Singh  , Santosh Kumar Bharti
Published: July 2024

The Model-View-Controller (MVC) architecture pattern has become a popular way to structure web applications, separating the data, presentation, and application logic into modular components. This review paper provides a comparative analysis of implementing MVC architecture using two major open-source server-side scripting languages - JavaServer Pages (JSP) and PHP. Over 10,000 open source projects utilizing JSP/Java and PHP are analyzed to compare how the languages lend themselves to the MVC pattern. The challenges and advantages of both platforms for real-world development of thin-client applications are assessed. Quantitative metrics on performance, scalability, code reuse and integration with MVC frameworks like Spring and Laravel are provided. The findings indicate strengths and weaknesses unique to both languages, with outcome being that PHP+Laravel offers faster initial development time, while JSP+Spring provides more enterprise-grade scalability. The insights can guide developers to make an informed choice between the two platforms for MVC-based, client-server application development.
Impact of Demonetization on Electronic Banking: An Analytical Study
Authors: Rizwana Begum  , A. Varalakshmi  , Mohammad Mona  , Mohammed Afreen Sana  , Moluguri Keerthi  , Momena Begum
Published: July 2024

This research investigates the multifaceted repercussions of demonetization on electronic banking, examining the transformative effects on financial systems and consumer behavior. Key components of the study include an assessment of the immediate and long-term impacts of demonetization on electronic banking adoption, transaction volumes, and security concerns. The analysis encompasses a comprehensive review of key financial indicators, regulatory changes, and technological advancements in the electronic banking landscape post-demonetization.
A Study on E-Marketing at eBay
Authors: Mrs. Rajitha Pathange  , Mrs. Rajani Parcha  , Jadhav Laharika  , Jallela Shirisha  , Jamirun Begum  , Jegiram Vani
Published: July 2024

This research aims to conduct a comprehensive study on E-Marketing practices employed by eBay, one of the leading e-commerce platforms globally. As the landscape of online marketing continues to evolve, understanding the strategies and approaches adopted by prominent players such as eBay becomes crucial. Employing a mixed-methods research design, including content analysis, surveys, and interviews, this study seeks to explore the various facets of eBay's E-Marketing initiatives.
Key objectives include analyzing the effectiveness of eBay's digital marketing strategies, assessing customer engagement tactics, and understanding the impact of E-Marketing on user acquisition and retention. The study also aims to identify innovative practices, challenges faced, and the integration of emerging technologies in eBay's E-Marketing efforts. The findings of this research are anticipated to provide valuable insights for eBay, e-commerce practitioners, and researchers interested in understanding the nuances of E-Marketing in the competitive online marketplace.
Demographics and job satisfaction as predictors of mental well-being of Filipino teachers
Authors: Oducado Ryan Michael , Amboy Mary Kristine , Robles Baby Rose , Rosano Daisy , Montaño Hilda , Temelo Dolly Rose , Penuela Ayesha , Salistre Arlyn , Ramirez Liza Marie , Tamdang Khen
Published: July 2024

Teachers worldwide have had to change how they work because of the COVID-19 health crisis. These work changes and pandemic challenges have affected teachers in one way or another. There is a need to investigate teachers' welfare and how contented they are with their jobs two years after the onset of the pandemic and nationwide lockdown. This study examined the factors predicting the subjective mental well-being of teachers in the Philippines. Using a cross-sectional study design, the survey responses of 218 Filipino teachers were analyzed. Data were gathered electronically using the demographic profile form, a short version of the Warwick–Edinburgh Mental Well-being Scale, and the Short Index of Job Satisfaction. Results indicated that the majority of teachers had average to high job satisfaction and average subjective mental well-being. Regression analysis revealed that the type of school employed, residence, and job satisfaction were significant predictors of the mental well-being of teachers. This study affirms that certain demographic variables and satisfaction at work exert a positive influence on the mental health of teachers. Continuously making improvements in the working conditions of teachers and devising ways to enhance their well-being are vital.
Economía circular transformadora y globalización neoliberal (y antropocénica)
Authors: Vence Xavier
Published: July 2024

Se analizan las relaciones complejas y contradictorias entre el proceso de globalización neoliberal -aceleradora del antropoceno- y las propuestas de una economía circular transformadora. El proceso de globalización neoliberal -guiado por las finanzas- de las últimas décadas expandió los flujos internacionales y, por lo tanto, el transporte en todas sus modalidades y escalas (internacional y local), con el consiguiente consumo de materiales y energía en su actividad, en la producción del stock de equipos, medios de transporte e infraestructuras, acelerando la huella de materiales y de emisiones. Esa expansión se debe no solo en un aumento del comercio internacional de materias primas o bienes finales, sino a la creciente fragmentación global de la producción, la globalización de los patrones de consumo, el consumo instantáneo (plataformas) y, finalmente, al posconsumo y los flujos de residuos. En este artículo se analizan las diferentes dimensiones de la articulación material de la globalización productiva y comercial desde la perspectiva de la EC transformadora, prestando especial atención al papel del transporte internacional (marítimo y aéreo) y las infraestructuras asociadas, tanto en términos de emisiones de CO2, como de huella de materiales, flujos de materiales secundarios y residuos, etc. El actual modelo económico lineal debe ser transformado en base estrategias de economía circular, que articulen sobre nuevas bases lo global y lo local, superando las estrategias de reverdecimiento -o simple "green washing"- formuladas por el crecimiento verde guiado por las finanzas.
Transformation of land relations in agriculture of the Republic of Kazakhstan: the impact of institutional changes on economic development
Authors: Satybaldin A. ,   Institute of Economics of the Science Committee of the Ministry of Science and Higher Education of the Republic of Kazakhstan, Ruzanov R. , Panzabekova A. ,   Institute of Economics of the Science Committee of the Ministry of Science and Higher Education of the Republic of Kazakhstan,   Institute of Economics of the Science Committee of the Ministry of Science and Higher Education of the Republic of Kazakhstan
Published: July 2024

Since Kazakhstan gained independence, transformation of land relations in agriculture has been inextricably linked with waves of privatization and introduction of market principles of management. The goal is to study the impact of institutional changes on the process of reforming land resources in agricultural sector of the republic. The methods are based on materials from domestic and foreign analytical reviews, scientific publications, regulations relating to the land issue, and program strategic documents. Quantitative and graphical methods were used to analyze the consequences of institutional reforms in agro-industrial complex in terms of property reorganization, land use, and contribution of agricultural production to the country's GDP. Results - it is substantiated that the breakup of production, logistics and other necessary connections in the first years of Kazakhstan’s independence became a difficult test for agriculture and the loss of significant investments in the gross domestic product by this industry. Modern reality required building new market rules, regulated by the state within the framework of laws. The main stages of regulatory changes that influenced land legal relations in agricultural sector are given. The consequences of past reforms related to the land issue are presented, problems and challenges facing the development of agro-industrial complex of the republic are identified, and recommendations are offered to improve the current situation. Conclusions - it should be understood that the quality of adopted regulations reflecting property rights, including land legislation, directly affects socio-economic and environmental situation, which shows the importance of the institutional system for the economic development of the country, formation of effective socio-economic structure of agricultural sector.
Pasture lands and food supply in the Mangistau region of Kazakhstan under drought conditions: searching for compromises, recommendations
Authors: Akhmetova G. Т. ,   Kh. Dosmukhamedov Atyrau University, Abdeshov D. D. , Aldeshova S. ,   Sh.Yesenov Caspian University of Technology and Engineering,   Kh. Dosmukhamedov Atyrau University
Published: July 2024

starvation of livestock in drought conditions resulting from pasture degradation. Methods - analysis and generalization of the legislation of Kazakhstan in the field of agriculture and land reclamation, Land Code based on data on the number of livestock in dynamics and share of regions in the overall country indicator. Results - issues of accessibility of pasture lands for grazing and food supply for animals in the Mangistau region were considered, facts of their death due to dystrophy caused by malnutrition were revealed. According to statistics, in 2022 there were 22.8 thousand heads of cattle, which is 4.2% less than in 2021, about 85.7 thousand heads of camels (increase by 6%), 120.5 thousand heads of horses (increase by 6.3%). Due to desertification and deterioration of pastures, the number of abandoned pastures is increasing. Conclusions - Innovative approaches are needed to address sustainable land management challenges, implementing strategies such as rotational plot systems that promote restoration of rangelands, allowing vegetation to rest between grazing periods in mountainous and foothill areas, which in turn maintains soil fertility and contributes to conservation of biodiversity. It is also necessary to grow drought-resistant forage desert plants adapted to climate change, this increases the availability of forage crops, balances livestock diets and reduces the load on ecosystems. The article proposes plans to expand pasture areas and their use, and develop projects in the field of feed production.
A formação de territórios inovadores: a abordagem do meio inovador
Authors: Natário Maria Manuela Santos
Published: July 2024

Nos últimos 30 anos, os aspectos regionais foram trazidos para a agenda das investigações em economia. Nas teorias económicas o espaço esteve sempre mais ou menos presente. Todavia, nas teorias tradicionais o espaço não tinha um papel activo na dinâmica da inovação, sendo remetido para segundo plano. A abordagem dos meios inovadores baseia-se na ideia de que o espaço, ou mais precisamente, o território tem um papel activo, fornecendo os meios para fomentar o desenvolvimento económico e que estes mecanismos económicos transformam o próprio território. Esta análise procura explicar porquê certas regiões tinham sucesso e eram mais dinâmicas que outras. Deste modo, o objectivo deste trabalho é apresentar a abordagem dos meios inovadores na formação de territórios inovadores e na promoção da competitividade territorial. Pretende-se assim clarificar o conceito de meio inovador bem como a sua evolução e identificar os aspectos mais relevantes da dinâmica territorial de inovação, procurando relacionar o paradigma dos meios inovadores com o desenvolvimento dos territórios no sentido de promover a competitividade das regiões.
Crescimento económico e dimensão dos governos: o caso português
Authors: Rei Constantino Mendes
Published: July 2024

Em Portugal, impera a visão de que o sector público é ineficiente, causador de má afectação de recursos, criando desincentivos vários e consequentemente, inibidor do crescimento económico. O objectivo deste trabalho é o de investigar, recorrendo à metodologia de cointegração e causalidade de Granger, até que ponto o papel do Estado em Portugal e em particular o peso do sector público (medido pelas despesas públicas) tem contribuído positiva ou negativamente para o crescimento económico português. Como primeira implicação destes resultados, resulta que os mesmos sustentam a linha de orientação da política económica dos últimos Governos, no sentido de reduzir o peso do Estado na economia portuguesa. Parece pois que as ineficiências do sector público português são importantes e que a inversão do ritmo de crescimento económico e a melhoria da produtividade podem de facto passar pela transferência de algumas actividades e funções do Estado para a iniciativa privada.
LEGAL FRAMEWORK FOR CONSUMER PROTECTION AND IMPROVEMENT OF PRODUCT QUALITY
Authors:   Belgrade Business and Arts Academy of Applied Studies, Serbia, Rašević Milica , Jakovljević Marija ,   Belgrade Business and Arts Academy of Applied Studies, Serbia, Radunović Slađana ,   Belgrade Business and Arts Academy of Applied Studies, Serbia
Published: July 2024

This study describes legal frameworks, strategies and activities for consumer protection and improvement of product quality. Focusing on various aspects, from analysis of existing laws to awareness promotion and consumer education, it explores how to improve the legal framework, identify challenges and develop effective strategies. Planning campaigns to raise awareness of consumer rights, as well as developing educational programs, are key elements in raising awareness and improving consumer education. Also, strengthening of institutional capacities for effective implementation of new legal measures is crucial for successful consumer protection and improvement of product quality. This study offers a comprehensive overview of the various strategies and activities that can be implemented to achieve the goals of consumer protection and product quality improvement
APPLICATION OF IT TECHNOLOGIES IN THE PHARMACEUTICAL INDUSTRY
Authors:   Farmaceutsko društvo Republike Srpske, Milanović Nataša
Published: July 2024

In the modern era, information technology (IT) is significantly transforming the pharmaceutical industry through the application of distance learning tools. These technologies enable pharmaceutical professionals to engage in continuous professional development regardless of location, tailored to individual needs and learning pace. This paper explores the advantages and challenges of these applications, including improvements in the quality of education, access to the latest information and methodologies, and enhanced coordination of healthcare teams. Additionally, the need for high-quality content and user data protection is emphasized for the effective implementation of these technologies. The integration of IT into pharmaceutical practice not only supports continuous professional development for pharmaceutical professionals but also improves team coordination and the speed of critical information exchange. With ongoing technological advancements, the prospects for further progress in the pharmaceutical industry are promising, creating opportunities to enhance patient health outcomes and, consequently, more effective healthcare services.