bluuebunny/crossref_metadata_2025 huggingface dataset:
Perioperative hyperbaric oxygen treatment and postoperative complications following secondary breast reconstruction after radiotherapy: a case-control study of 45 patients
Authors:   Department of Plastic Surgery, Radboud University Medical Center, Nijmegen, The Netherlands, Meier Eva L , Hummelink Stefan ,   Department of Plastic Surgery, Radboud University Medical Center, Nijmegen, The Netherlands, Lansdorp Nina ,   Da Vinci Clinic, Arnhem, The Netherlands, Boonstra Onno ,   Da Vinci Clinic, Arnhem, The Netherlands, Ulrich Dietmar JO ,   Department of Plastic Surgery, Radboud University Medical Center, Nijmegen, The Netherlands
Published: September 2021

Introduction: Radiotherapy reduces the risk of locoregional recurrence of breast cancer. As a side-effect, tissue can become hypocellular, hypovascular, and hypoxic and late radiation tissue injury can develop months or years later. Radiotherapy increases the risk of complications following secondary breast reconstruction. Hyperbaric oxygen treatment (HBOT) improves oxygenation of irradiated tissue and induces neovascularisation. This study evaluated whether the incidence of complications following secondary breast reconstruction after radiotherapy is decreased with perioperative HBOT. Methods: In this retrospective case-control chart review study, patients who underwent perioperative HBOT (n = 15) were compared to lifestyle-matched (n = 15) and radiation damage-matched (n = 15) patients who underwent secondary breast reconstruction without HBOT. Results: The HBOT group had significantly more severe radiation damage of the breast than the lifestyle- and radiation-damage-matched control groups (scoring grade 1-4, mean 3.55 versus 1.75 and 2.89 respectively, P = 0.001). Patients underwent on average 33 sessions of HBOT (18 sessions preoperatively and 15 sessions postoperatively). There was no significant difference in the incidence of postoperative complications between the HBOT group, lifestyle-matched group and radiation damage-matched group. Logistic regression analysis showed a lower risk of postoperative complications in patients who underwent HBOT. Conclusions: Although the HBOT group had more radiation damage than the control groups, the incidence of postoperative complications was not significantly different. This implied a beneficial effect of HBOT, which was supported by the logistic regression analysis. Definitive conclusions cannot be drawn due to the small sample size. Future research is justified, preferably a large randomised controlled trial.
Lipoma arborescente bilateral de hombro: manejo de un caso en consulta de rehabilitación y revisión de la literatura
Authors: Vaamonde Lorenzo Lucía , García-Macero René Antonio , Díez Bandera Rubén , López Moya Antonio , Juan García Francisco Javier
Published: September 2021

La lipomatosis arborescente, también conocida como ‘proliferación de vellosidades de la membrana sinovial’, es una entidad que se caracteriza por la proliferación difusa de vellosidades con reemplazo del tejido sinovial por adipocitos maduros. La presentación típica es una enfermedad monoarticular que afecta a la rodilla, con predilección por la bolsa suprapatelar, aunque también se describe afectación mono o biarticular de articulaciones grandes como las caderas, los tobillos, los codos y los hombros. La resonancia magnética nuclear (RMN) es el método de imagen de elección para hacer el diagnóstico. El tratamiento consiste en practicar sinovectomía, ya sea abierta o artroscópica. En este estudio se presenta un caso de lipoma arborescente con afectación simultánea de la bursa subacromial-subdeltoidea, vaina del tendón de la porción larga del bíceps y articulación glenohumeral, que se asoció a lesión del manguito de los rotadores valorado en la Unidad de Alta Resolución de Hombro de nuestro servicio de rehabilitación.
THE PHENOMENON OF POLITICIZATION OF ETHNICITY IN THE CONTEXT OF ETHNOPOLITICAL PROCESSES OF THE COLLAPSE OF THE USSR (ON THE EXAMPLE OF SOUTH OSSETIA)
Authors:   South Ossetian State University Tshinval, Sanakoev Inal B.
Published: September 2021

The author analyzes the phenomenon of politicization of ethnicity in the conditions of the collapse of the USSR on the example of South Ossetia. The study of this phenomenon is carried out by the author in the aspect of ana- lyzing the mass public sentiment in South Ossetia on the eve of the Georgian- Ossetian conflict, which became a kind of socio-political background and also the aggravation of the internal political struggle in the republic.
THE ROLE OF PUBLIC ORGANIZATIONS IN THE PROTECTION OF THE RIGHTS OF THE INDIGENOUS SMALL-NUMBERED PEOPLES OF THE NORTH (BASED ON THE MATERIALS OF AN EXPERT SURVEY IN THE KHANTY-MANSI AUTONOMOUS OKRUG – YUGRA)
Authors:   Surgut State University, Martynov Mikhail Yu. , Serdyukov Dmitry V. ,   Surgut State University
Published: September 2021

The article is devoted to the study of the state of institutional support for the rights of the indigenous peoples of the North. The industrial development of Siberian territories creates a threat of destruction of traditional forms of economic management. This makes this problem actual. The empirical material is the results of an expert survey conducted on the territory of the Khanty-Mansiysk Autonomous Okrug – Yugra. It is concluded that a regula- tory and legal framework has been created in the region to ensure the interests of indigenous peoples. However, it only creates an opportunity to protect their interests. This opportunity can be fully realized through the activities of political institutions. Today, public organizations of the indigenous peoples themselves are effectively working. They enjoy the trust of the indigenous population and protect not only the rights of Aboriginal people to traditional forms of farming, but also their socio-economic interests in general. However, the capabilities of these organizations are rather limited. For example, small indigenous peoples, due to their small number, do not have the opportunity to conduct “their” deputies to representative bodies of power. At the same time, the role of other actors – political organizations, mass media, ombudsmen – is insignificant. Expanding the range of political institutions involved in protecting the rights of the indigenous peoples of the North is the main condition for the successful solution of this task.
Derecho indígena comparado: el derecho indígena desde sus propios parámetros
Authors: Cruz Rueda Elisa , Elizondo Zenteno María del Pilar
Published: September 2021

El interés de este artículo es mostrar la importancia del estudio del derecho indígena desde sus propios parámetros. Se presentan los resultados de la revisión de estudios desde la Antropología y el Derecho sobre los sistemas normativos indígenas. A partir de esto se concluye que para hacer efectivo el pluralismo jurídico y el reconocimiento de la pluriculturalidad de México de acuerdo con la Constitución Política de los Estados Unidos Mexicanos, art. 2º, es necesario el estudio del derecho indígena desde sus propios parámetros; de lo contrario, cualquier diálogo que pretenda ser intercultural en realidad seguiría reproduciendo esquemas de imposición de la cultura hegemónica sobre el resto de los pueblos que conforman la nación mexicana.
Commentary: Management of Refractory Pain After Total Joint Replacement
Authors: Heimroth Jamie , Willinger Max L. , Sodhi Nipun , Garbarino Luke J. , Gold Peter A. , Danoff Jonathan R. , Boraiah Sreevathsa
Published: September 2021

Chronic refractory pain after total joint replacement is debilitating and a source of dissatisfaction for patients. The management of pain following total joint replacement varies during the acute postoperative period compared to the 3 months postoperative at which point the pain is considered chronic pain. Acute postoperative pain relief programs have seen promising results with multimodal pain control through the use of combinations of opioids, acetaminophen, nonsteroidal anti-inflammatory drugs, gabapentinoids and ketamine. The addition of regional blocks to the multimodal regimen has improved acute postoperative pain control following total joint replacements. On the other hand, chronic pain can be successfully managed with options including genicular nerve radioablation therapy (GN-RFA), neuromuscular electrical stimulation (NMES), transcutaneous electrical nerve stimulation (TENS), and peripheral subcutaneous field stimulation (PSFS). While there is still minimal data on chronic pain relief regimens, meta-analyses and case reports have demonstrated the effectiveness and promising outcomes. This paper aims to evaluate the current medications and treatment options for managing refractory pain following TJA.
O projeto de humano da modernidade
Authors: Moreira Alberto
Published: September 2021

Em primeiro lugar devo manifestar o desconforto de parecer um pouco um “especialista do geral”. Com efeito, o grau de generalidade contido no título dessas reflexões — O projeto de humano da modernidade — é de tal monta que a tarefa se torna de todo impossível, se não for colocada desde o início sob o signo da precariedade e do esforço coletivo. Em segundo lugar acredito ser necessário mencionar desde já algumas objeções que poderiam surgir quanto à propriedade e ao conteúdo da questão a ser tratada...
The impact of Syrian refugees on patient demographics and type 2 diabetes across five public health centers in Lebanon
Authors: Makhoul Peter , Tcheroyan Raya , Ammar Walid , Hamadeh Randa , Zalloua Pierre , Nabbout Ghassan
Published: September 2021

Background

The war in Syria triggered the influx of a large number of refugees into neighboring countries, particularly Lebanon. In 2019, the Syrian population made up 13.33% of the total population in Lebanon. This shift in demographics influenced many sectors in the country, including the healthcare system.

The purpose of this study is to analyze the impact of Syrian refugees on the Lebanese healthcare system across five public health centers (PHCs) and the prevalence of type II diabetes (T2D) in these patients.

Methods

Patient data was collected across five PHCs from different regions in Lebanon. Comparisons between Lebanese and Syrian patients were analyzed for demographics, relative number of patients, and prevalence of T2D.

Results

We found that the number of patients admitted to PHCs has increased over the last few years, in both Syrian and Lebanese populations, putting more strains on an already threatened sector. In addition, the increase in Lebanese patients is significantly higher after 2015, and it parallels the surge in Syrian immigrants. The prevalence of T2D was found to be increasing over the years among the two populations, with a statistically significant increase in the Lebanese population after 2015. However, the prevalence of T2D was found to be statistically lower than the reported national prevalence in both groups, possibly due to inadequate rates of screening.

Conclusions

There has been an increase in admissions to PHCs as well as rates of T2D in Lebanon and in the Syrian population. Inadequate screening could be the reason behind the lower prevalence of T2D in our study compared to the reported national prevalence.
Household factors associated with managing the HIV positive population and meeting the UNAIDS goals
Authors: Gaumer Gary , Ochigbo Ekwu B. , Sherafat-Kazemzadeh Roya , Daniels Elad , Brown Jessica , Hurley Clare L. , Nandakumar A. K.
Published: September 2021

Background

While poor countries have made progress attaining the The Joint United Nations Programme on HIV/AIDS (UNAIDS) goals for 2025, continued progress depends on continued accessibility of program services, as well as continued improvements in compliant behavior by HIV positive populations. This paper examines household survey data in four African countries pertaining to those critical behaviors and identifies the key population barriers for attaining UNAIDS goals.

Methods

This study used Population-based HIV Impact Assessment (PHIA) survey data for Zambia, Malawi, Eswatini, and Tanzania to examine household and other influences associated with effectively managing HIV-infected adults using three key outcomes: (i) self-awareness of HIV status, (ii) antiretroviral therapy adherence, and (iii) rate of viral load suppression (VLS).

Results

Factors found to increase HIV risk also posed barriers to awareness and viral suppression, such as being young, having multiple partners, and having a job outside the home. Additional barriers to awareness and viral suppression were low education, low wealth, low knowledge of HIV, and the HIV status and gender of the household head. The most consistent factor influencing awareness and viral load suppression was the gender of the individual. Women were much more likely to be aware of their HIV status and more likely to be virally suppressed at rates almost twice as high as comparable men. Our analysis shows that the gender differential for awareness seems primarily due the testing and other services provided for women giving birth. We also found that the VLS gender gap was not related birthing-related services.

Conclusions

The most substantial barrier to achieving UNAIDS goals appears to be poorer compliance by men regarding testing and sustained VLS. Routinely providing HIV testing and other HIV information during antenatal care (ANC) may have contributed to improved rates of HIV-status awareness of birthing-age women. New programs to routinely integrate HIV testing into men’s health care in workplaces or other settings could improve men’s awareness and compliance with treatment. Also needed are more effective interventions to target sectors of the population that are less likely to adhere to treatment regimens, such as persons with low-education levels, low wealth, and/or low knowledge of HIV.
İstatistik Öğretiminde Yeni Bir Yaklaşım: Doğada Uygulamalı İstatistik
Authors: ÖZEL Gamze , ÜNAL Ceren , DÜZ Yeter , ÖZKAN Kürşad
Published: September 2021

Günümüz Türkiye’sinde istatistik konuları ağırlıklı olarak matematik öğretim programlarında yer almaktadır. Son yıllardaki teknolojik ve bilimsel ilerlemeler sonucunda yığınlar halindeki ham veri ve bilgi trafiği nedeniyle meydana gelen karmaşa verilerin analizi ve yorumlanmasını daha da önemli hale getirmiştir. Bu yüzden, öğretim programlarında istatistiksel yöntem ve araçlara daha çok ihtiyaç duyulmaktadır. Bu çalışmada, TÜBİTAK 4004 Doğa Eğitimi ve Bilim Okulları kapsamında gerçekleştirilen “İstatistiği Doğada Öğren” projesinin istatistik öğretiminde sağladığı ve sağlayacağı faydalar üzerinde durulmuştur. Araştırmanın örneklemini projeye katılan farklı branşlardaki 36 öğretmen oluşturmaktadır. Proje kapsamında, istatistiğin doğa uygulamaları ve örnekleri ile ilgili etkinlikler gerçekleştirilmiştir. Projenin öğretmenler üzerindeki etkisini ölçmek için proje araştırmacıları tarafından oluşturulan etkinlik değerlendirme formları, röportajlar ve mini test uygulamaları kullanılmıştır. Ayrıca, öğretmenlerin proje sonrasındaki kurgusal eğitim örnekleri ve yaptıkları görsel sanat çalışmaları incelenmiştir. Projedeki etkileşimli ve doğaya dayalı istatistiksel uygulamaların ve verinin yazılımlar ile görselleştirilerek aktarılmasının öğretmenleri pozitif yönde etkilediği, öğretmenlerin öğrenme ve araştırma isteklerini arttırdığı gözlenmiştir.
Toxicity of raw and bio slurry treated oily sludge on Nitrobacter species and Tilapia guineensis
Authors: Nsikak A. Abraham  , Lucky O. Odokuma  , Gideon C. Okpokwasilli
Published: September 2021

Toxicity of raw and bio-slurry treated oily sludge (OS) on Nitrobacter species was determined using standard analytical procedures. The total petroleum content of the OS was 116.44 ± 3.57 g/kg. The TPH was rich with Saturate (40.46 ± 0.73 %). This was followed by Aromatics (27.94 ± 0.50 %) and Asphaltenes (26.58 ± 0.90 %), while NSO fraction had the least proportion (5.75 ± 0.47 %). Contamination of coastal soil with the OS increased the residual TPH concentration in the soil from 5.0561 ppm to 24.2305 ppm. The OS-ladened soil were subjected to biodegradation using 1.5-litter borosilicate glass bioreactors bioaugmented with single population of known OS utilizer (Pseudomonas aeruginosa) and consortium of known OS utilizer and biosurfactant producing bacterial species (Bacillus subtilis). Findings revealed that he bioslurry augmented with the bacterial consortium reduced the concentration of the residual TPH in the soil to 6.313 ppm (73.95% reduction) while 11.5751 ppm (52.23%) was recorded for the single bacterial population. Findings also revealed that the consortium were able to remarkable reduce the toxicity of the raw OS (LC50 = 20.94 ppt) on Nitrobacter species. The LC50 for the consortium treated OS was 104.64 ppt while that of single bacterial population treatment was 36.25 ppt. The reduction in the toxicity of the OS treated with the bacterial consortium indicates the potentials of the synergistic action between the biosurfactant producer and OS utilizer to reduce OS toxicity. The findings of this study can be explored as a cost-effective method for oily sludge waste management in the Oil and Gas industry.
Acute and chronic toxicity evaluation of methanol leaf extract of Psidium guajava (Myrtaceae)
Authors: Joy Ogugua Igwe  , Harrison Odera Abone  , Moses Chukwuemeka Ezea  , Chika Peter Ejikeugwu  , Charles Okechukwu Esimone
Published: September 2021

The medicinal value of herbal plants have been widely described in a number of studies, this has resulted in their increased usage. This study aimed to evaluate the safety of methanolic leaf extract of Psidium guajava extract in albino rats using biochemical, hematological and histological parameters. In acute toxicity, the extract was administered orally up to 5,000 mg/kg body weight once to male albino mice. While in chronic toxicity, twenty four adult male albino rats were randomly divided into four groups of six rats for each group. The control group received 10 ml/kg body weight distilled water daily. The other groups received 50, 200 and 400 mg/kg body weight of extract daily for 90 days. All the rats were observed daily for signs of toxicity and mortality. At the end of the treatment period, biochemical and hematological tests were carried out on prepared sera. Histology of vital organs was evaluated. Acute toxicology showed the LD50 of the extract to be less than 5000 mg/kg. Chronic toxicological study revealed that at 200 mg/kg, there was no significant (P > 0.05) differences in hematological and biochemical parameters, and there was no alterations in the histology of the organs. However, at 400 mg/kg body weight, the concentrations of the liver biomarkers were increased, with distorted liver. Since no alterations was observed at 200 mg/kg, the extract may be considered to be relatively safe at this dose and could be used for long term treatment of infections.
Are there any links between blood statuses of vitamin B12, B9, and D with depression in the elderly population living in nursing homes? A descriptive-analytical study from Tehran-Iran
Authors: Lyly Nazemi  , Ingvar Karlsson  , Ingmar Skoog  , Margda Waern  , Mostafa Hosseini  , Mohammad Reza Mohammadi  , Ali Akbar Sabour Yaraghi  , Zahra Farahani
Published: September 2021

Background: Nutritional deficiency has been suggested as a cause of depression in old age. The present study was performed to evaluate statuses of vitamin B12, Folate (vitamin B9), and vitamin D and their associations with depression among the elderly population living in nursing homes in Tehran-Iran. Methods: One-hundred and seventy subjects from 17 randomly selected nursing homes (NH) (Tehran-Iran) were enrolled in the study. Depression, nutritional statuses, history of chronic diseases, dental health, the levels of exposure to sunlight, the level of satisfaction associated with food quality, and NH staff were evaluated for determining possible relations between depression with vitamin B12, Folate, and vitamin D levels. Results: In the present study Folate and vitamin D deficiencies were found in 96% and 56% of subjects. No correlations were observed between depression with vitamin B12 (P=0.47), Folate (P=0.16) and Vitamin D (P=0.24) levels. Conclusion: The results delineate the high prevalence of vitamin deficiencies among elderly nursing home residents; however, no associations were observed between depression and these nutritional factors. Further studies considering other risk factors and more nutritional micronutrients are suggested.
The use of starter cultures in the meat industry and their effect on the quality of meat products – A review
Authors: Dragutin Djukić  , Monika Stojanova  , Slavica Vesković-Moračanin  , Marina Todor Stojanova  , Aziz Şatana
Published: September 2021

The use of certain types of microorganisms or their metabolic products is the basis for the development of new technologies, which on the one hand can contribute to the standardization of the production process and achieve uniform quality, and on the other hand to obtain quality and safe products with extended shelf life. On the world market for food and beverages, today can be find a wide range of commercial, fermented products in which production and sustainability certain microorganisms are participate. The interest in the new methods of biological protection of food, as well as the scientific principles for achieving health of the products has increased significantly in recent years. The increase in the need for quality and health-safe food has led to an increased interest in the use of starter cultures in the food industry, and especially in the meat industry. With the use of the starter cultures, good quality of the products is achieved. At the same time a safe product is obtained, where the use of the synthetic additives and theirs side effects on consumer’s health is completely eliminated.
School Policy in Improving Discipline Character of Elementary School Students
Authors: Sudaryono Sudaryono , Aryani Ine Kusuma
Published: September 2021

This research was conducted to find out, explore, study, and describe the implementation of disciplinary character education in elementary schools and expected to help find the right policies to support the successful implementation of character education. The type of data used is secondary data. This research uses the literature study method. The data obtained were collected, analyzed, and concluded obtain conclusions about the literature study. Based on the research results, literature studies from several research results and journal articles indicate that implementation school policies by establishing good cooperation between all school residents and school committees can increase the success of the implementation of character education in elementary schools.
Overview of Nonhuman Primate Models of SARS-CoV-2 Infection
Authors: Trichel Anita M
Published: September 2021

COVID-19, the disease caused by the SARS-CoV-2 betacoronavirus, was declared a pandemic by the World Health Organization on March 11, 2020. Since then, SARS-CoV-2 has triggered a devastating global health and economic emergency. In response, a broad range of preclinical animal models
have been used to identify effective therapies and vaccines. Current animal models do not express the full spectrum of human COVID-19 disease and pathology, with most exhibiting mild to moderate disease without mortality. NHPs are physiologically, genetically, and immunologically more closely
related to humans than other animal species; thus, they provide a relevant model for SARS-CoV-2 investigations. This overview summarizes NHP models of SARS-CoV-2 and their role in vaccine and therapeutic development.
Cómo aprendemos el profesorado de universidad. Implicaciones para la formación docente
Authors: Sancho-Gil Juana María , Correa Gorospe José Miguel , Ochoa-Aizpurua Aguirre Begoña , Domingo-Coscollola María
Published: September 2021

Este artículo se basa en un proyecto de investigación coordinado sobre cómo aprenden los docentes, sus implicaciones educativas y los retos para afrontar el cambio social. Desde un posicionamiento basado en la investigación inclusiva y la utilización de métodos visuales se crearon 65 cartografías sobre los escenarios o contextos de aprendizaje de docentes de educación infantil, primaria, secundaria y superior (en este caso los investigadores del proyecto). También, se compartieron las explicaciones y reflexiones sobre las cartografías realizadas dando cuenta de los tránsitos y experiencias de aprendizaje. En este artículo, presentamos los resultados y las conclusiones sobre cómo aprendemos los docentes de educación superior, centrados en los autores de este texto. Destacamos las posibilidades de la experiencia cartográfica para la investigación educativa y la consideración de que el aprendizaje del profesorado no solo tiene lugar en contextos formales e institucionales, sino a lo largo y ancho de la vida. Elaboramos conclusiones sobre las características del aprendizaje del profesorado actual y sobre la importancia de tener en cuenta su carácter contextual, biográfico, corporeizado y socioafectivo en la formación inicial y permanente de los docentes. También avanzamos algunas implicaciones para repensar la formación docente al considerar las relaciones entre las experiencias de vida y el aprendizaje, la importancia de conectar las instituciones educativas con la sociedad, la reflexión sobre la práctica educativa y los principales desafíos educativos. Todo ello con la finalidad de promover la transformación de los centros educativos en instituciones de aprendizaje con sentido.
MANAGEMENT MODEL OF ECOTOURISM-BASED FOREST VILLAGE COMMUNITY LAND TO INCREASE LOCAL ECONOMIC IN KARANGANYAR, INDONESIA
Authors:   Universitas Negeri Malang, Faculty of Social Science, Sociology Department, Indonesia, FIBRIANTO Alan Sigit
Published: September 2021

Berjo Village has the potential for ecotourism which can increase the economic potential of its people. This study aims to determine how Berjo Village manages the potential of natural tourism, agricultural tourism, and improves the economy of forest village communities. The method used is qualitative with a case study approach and triangulation as data validity, and interactive techniques as analysis. The results showed that the economic sector of the people of Berjo Village came from agriculture and tourism. The location of the forest area has high potential to be developed into ecotourism, which consists of Sukuh Temple, Jumog Waterfall, Telaga Madirda, Forest Park, Tenggir Park, Camping Ground or Outbound Tourism, Planggatan Site, Kampung Gunung Palace, Berjo Hydroponics, Ornamental Flower and Cut Flower Centers, Horticultural Plant Nursery Centers, the potential for climbing Mount Lawu by making a basecamp for prospective mountain climbers. All tours are in one location, namely, Berjo Village as an ecotourism destination. Tourism management is carried out by applying the concept of empowerment and the existence of embeddedness among various stakeholders with all the potential for ecotourism in an effort to improve the lives of the people in Berjo Village, Karanganyar Regency, Indonesia.
Interações medicamentosas graves em intoxicações por paracetamol no Brasil: estudo transversal baseado no Sistema Nacional de Agravos de Notificação
Authors: LAGEMANN Letícia M. , OKUYAMA Julia H. , SILVA Marcus T.
Published: September 2021

Objetivo: Descrever as intoxicações de paracetmol associadas a outros medicamentos e analisar os fatores associados às interações medicamentosas graves. Métodos: Foram analisados os casos de intoxicação envolvendo paracetamol disponíveis no Sistema de Informação de Agravos de Notificação de 2017. Foram excluídos os registros contendo associação com agrotóxicos, alimentos, álcool e drogas de abusos. Os medicamentos relacionados às intoxicações foram identificados, codificados e agrupados de acordo com a classificação Anatomical Therapeutic Chemical. A intensidade da interação foi analisada para determinar a gravidade de acordo com o Micromedex®. Para investigar os fatores associados às interações medicamentosas graves, estimamos as razões de prevalência (RP) por regressão de Poisson, a qual considerou as seguintes variáveis: região, faixa-etária, sexo, etnia, mês de ocorrência, dia da semana, associação com analgésicos, associação com antiinflamatórios e tentativas de suicídio. Resultados: Em 2017, foram identificadas 763 notificações de intoxicações por paracetamol com outros medicamentos. Ocorreram 5,6 casos de tentativa suicídio por um caso não intencional. A análise multivariada indicou que as interações medicamentosas graves foram mais frequentes na idade maior que 37 anos (RP = 2,73; IC 95% 1,35-5,54), usuários de analgésicos (RP= 2,56; IC 95% 1,52-4,3) e usuários de antiinflamtórios (RP = 4,04; IC 95% 2,41-6,78). Conclusão: Interações medicamentosas graves em casos de intoxicação por paracetamol têm sido associadas a analgésicos, anti inflamatórios, adultos e tentativas de suicídio.
The Intelligent Auto-Tuning Controller Design Based on Dolphin Echo Location for Blood Glucose Monitoring System
Authors: Hameed Rabab Alaa
Published: September 2021

This paper presents an enhancement technique for tracking and regulating the blood glucose level for diabetic patients using an intelligent auto-tuning Proportional-Integral-Derivative PID controller. The proposed controller aims to generate the best insulin control action responsible for regulating the blood glucose level precisely, accurately, and quickly. The tuning control algorithm used the Dolphin Echolocation Optimization (DEO) algorithm for obtaining the near-optimal PID controller parameters with a proposed time domain specification performance index. The MATLAB simulation results for three different patients showed that the effectiveness and the robustness of the proposed control algorithm in terms of fast generating insulin control action and tracking the dynamics behavior of the blood glucose level of the diabetic patients through minimizing overshoot, rise time and settling time in the transient state as well as the steady-state blood glucose level error is reduced approximately to zero and keep it in the desired glucose level, especially when we added a meal as disturbance effect.
Seismic Vulnerability Assessment of Rizgary Hospital Building In Erbil City, the Capital City of KR of Iraq
Authors: Abduljaleel Zina A. , Taha Bahman Omer , Yaseen Abdulhameed Abdullah
Published: September 2021

Collapsing building structures during recent earthquakes, especially in Northern and Eastern Kurdistan, including the 2003 earthquake in Cewlig; the 2011 earthquake in Van; and the 2017 earthquake near Halabja province, has raised several concerns about the safety of pre-seismic code buildings and emergency facilities in Erbil city. The seismic vulnerability assessment of the hospital buildings as emergency facilities is one of the necessities which have a critical role in the recovery period following earthquakes. This research aims to study in detail and to extend the present knowledge about the seismic vulnerability of the Rizgary public hospital building in Erbil city, which was constructed before releasing the seismic provisions in the region.  ETABS software is employed to conduct Eigenvalue analyses, nonlinear static analyses, and about 120 incremental dynamic analyses; furthermore, the actual response of the hospital building is evaluated by considering possible irregularities in both directions and the effect of seismic pounding. The outcomes of the research indicate that the hospital building is in poor performance under anticipated earthquakes. In addition, the existing combination of irregularities and seismic pounding in the model increases the vulnerability under the seismic load. A suitable strengthening strategy is also recommended.
Thermal Buckling of Laminated Composite Plates Using a Simple Four Variable Plate Theory
Authors: Yahea Hussein Tawfeeq , Majeed Wedad Ibraheem
Published: September 2021

In this study, the thermal buckling behavior of composite laminate plates cross-ply and angle-ply all edged simply supported subjected to a uniform temperature field is investigated, using a simple trigonometric shear deformation theory. Four unknown variables are involved in the theory, and satisfied the zero traction boundary condition on the surface without using shear correction factors, Hamilton's principle is used to derive equations of  motion depending on a Simple Four Variable Plate Theory for cross-ply and angle-ply, and then solved through Navier's double trigonometric sequence, to obtain critical buckling temperature for laminated composite plates. Effect of changing some design parameters such as, orthotropy ratio (E1/E2), aspect ratio (a/b),  thickness ratio (a/h), thermal expansion coefficient ratio (α2/α1), are investigated, which have the same behavior and good agreement when compared with previously published results with maximum discrepancy (0.5%).
Evaluation of Drinking Water Quality in Al Wahda Treatment Plant in Baghdad City- Iraq
Authors: Mohammed Nisreen Yaseen , Adel Abdulrazzaq Khalid
Published: September 2021

This study aims to evaluate drinking water quality at the Al Wahda plant (WTP) in Baghdad city. A conventional water treatment plant with an average flow rate of 72.82 MLD. Water samples were taken from the influent and effluent of the treatment plant and analyzed for some physicochemical and biological parameters during the period from June to November 2020. The results of the evaluation indicate that treated water has almost the same characteristics as raw water; in other terms, the plant units do not remove pollutants as efficiently as intended. Based on this, the station appears to be nothing more than a series of water passage units. However, apart from Total dissolved solids, the mean values of all parameters in the study were of acceptable quality in accordance with World Health Organization (WHO) guidelines.
Spike neural network as a controller in SDN network
Authors: Majeed Anwar Dhyaa , Al-Jamali Nadia Adnan Shiltagh
Published: September 2021

The paper proposes a methodology for predicting packet flow at the data plane in smart SDN based on the intelligent controller of spike neural networks(SNN). This methodology is applied to predict the subsequent step of the packet flow, consequently reducing the overcrowding that might happen. The centralized controller acts as a reactive controller for managing the clustering head process in the Software Defined Network data layer in the proposed model. The simulation results show the capability of Spike Neural Network controller in SDN control layer to improve the (QoS) in the whole network in terms of minimizing the packet loss ratio and increased the buffer utilization ratio.
Sorption interactions in system «hydroxyapatite—aqueous solution of CuSO4»
Authors:   Mari State University, Smotrina T.V. , Stoyanov O.V. ,   Kazan National Research Technological University
Published: September 2021

Regularities of adsorption of copper (II) ions by synthetic hydroxyapatite have been examined. It is shown that sorption of metal ions occurs mainly in the mixed diffusion region, the chemical interaction described by the pseudo-second order kinetic equation has a significant effect on the process speed. It was found out that that the adsorption isotherm was described by the Langmuir monomolecular adsorption equation in the best way. Interaction specificity of hydroxyapatite with water was studied by NMR relaxation spectroscopy method
The effectiveness of cold compresses for reducing perinium wound pain
Authors: Nababan Lolli , Ningsih Sari Widya
Published: September 2021

The purpose of this study is to determine the relationship between the independent variable and the dependent variable. Observe before and after cold compress on the sample to be selected. Determines whether Ho will be accepted or rejected and Ha accepted, and vice versa. The number of samples was 30 postpartum mothers with grade I and II episiotomy wounds. The results of the univariate analysis showed that from 30 respondents, 0% of respondents who experienced very mild pain became 11 respondents (36.7%) after cold compresses, 15 respondents (50%) had mild pain to 13 (43.3%), pain moderate as many as 10 (33.3%) respondents to 6 (20%) respondents, severe pain as many as 5 respondents (16.7%) to 0 respondents. The result of p-value = 0,000, which means there is an effect of cold compresses on the healing of perineal wounds.
Dukungan Pada Lansia Dalam Menghadapi Pandemi Covid-19
Authors: Satriyandari Yekti , Utami Fitria Siswi
Published: September 2021

Kasus COVID-19 semakin bertambah. Muhammadiyah memberikan edukasi kesehatan. Tujuan penelitian melihat dukungan kelompok meliputi ekonomi, kesehatan, mental, dan sosial dalam menghadapi pandemi covid 19 di kelompok Ranting â€˜Aisyiyah. Jenis penelitian deskriptif kualitatif fenomenologi. Jumlah 13 informan denganÂ  Focus Group Discucssion. Hasil penelitian memberikan dukungan pada lansia selama pandemic covid 19 dengan memberikan paket sembako, saling mendukung satu sama lain, tidak memberikan stigma yang buruk pada masyarakat yang sedang melakukan isolasi mandiri. Meningkatkan peran kelompok dukungan social untuk meningkatkan derajat kesehatan lansia selama pandemic covid 19 menjadi rekomendasi dari penelitian ini.
Enhancing the performance of students in chemistry through flipped classroom with peer instruction teaching strategy
Authors: Macale Aprhodite , Lacsamana Marivic , Quimbo Maria Ana , Centeno Edmund
Published: September 2021

This study examines the implementation of flipped classroom with peer instruction teaching strategy to Grade 7 public high school students in Laguna, Philippines.  To analyze the effect of flipped classroom with peer instruction on Chemistry achievement, a two-group quasi-experimental pretest-posttest research design was used. In addition, student perception and participation were conducted using a post-implementation survey. In the flipped classroom with peer instruction, the students were introduced to the lesson using the science courseware developed by the Department of Science and Technology and YouTube videos as pre-class activities. The in-class activity was focused on answering concept questions through peer instruction. Findings show that the two groups of students significantly increased their Chemistry achievement after the implementation of the teaching strategies. However, the students in the flipped classroom with peer instruction had higher Chemistry achievement, high level of participation, and wide acceptance of the teaching strategy than the control group. With this teaching strategy, the students were able to complete their assigned tasks on time, show cooperative and supportive attitude during classroom discussion and activities, share ideas in class, and show respect for the opinion of others. On the contrary, students in the traditional classroom with peer instruction setup performed poorly on these aspects of classroom participation.
STRATEGI KOMUNIKASI POLITIK PASANGAN “SAYANG” MELALUI MEDIA MASSA (STUDI KASUS PILGUB SULSEL 2007)
Authors: AR Muhammad Yusuf
Published: September 2021

Penelitian ini bertujuan untuk mengetahui bagaimana strategi kampanye pasangan Syahrul Yasin Limpo-Agus Arifin Nu’mang yang disingkat ”Sayang” sebagai kandidat gubernur dan wakil gubernur Sulawesi Selatan periode 2008-2013 melalui media massa, serta mengetahui aspek-aspek persuasi dan daya tarik pesan yang dikemas tim pemenangannya melalui media massa. Penelitian ini menggunakan metode penelitian kualitatif yang bersifat interpretif dengan pendekatan studi kasus. Hasil penelitian menunjukkan bahwa tim yang solid di bawah komando master campaign, kemasan pesan serta tagline-nya yang cerdas dan tepat, seperti Don’t Look Back, “Berubah untuk Sejahtera”, “Sehat-Muda-Cerdas” merupakan pesan persuasif yang sengaja disebarkan ke tengah publik untuk menopang program unggulan utama “Sayang”, yakni pendidikan gratis dan kesehatan gratis yang kemudian berhasil menggulingkan petahana; pasangan “Asmara” (HM Amin Syam-H Mansyur Ramly).
DAMPAK DARI SAMPAH RUMAH TANGGA MENGAKIBATKAN PENCEMARAN LINGKUNGAN
Authors: Azizah Nur
Published: September 2021

Sampah merupakan bentuk dari material yang tidak memiliki nilai ataupun harga, karena sampah merupakan benda yang telah tidak dipakai atau telah dibuang oleh pemiliknya. Dengan begitu terjadinya sebuah penumpukan sampah dan menyebabkan lingkungan disekitar kita seperti jalanan, sungai, selokan, dan lain sebagainya. Sampah juga dapat dikatakan sebagai limbah rumah tangga mengapa begitu karena sampah berasal dari kegiatan sehari-hari. Banyak sekali dampak yang ditimbulkan dari limbah sampah baik itu penyakit bahkan kerusakan lingkungan menjadi tidak aman dan nyaman. 3R menjadi salah satu solusi, selain itu kampanye untuk tidak membuang sampah sembarangan harus terus dilakukan, terutama di daerah yang sudah disurvei tingkat kepeduliannya terhadap lingkungan sekitarnya kurang. Benar jika lingkungan rumahnya bersih akan tetapi, lingkungan alam sekitarnya menjadi rusak dikarenakan tindakan itu. Metode yang digunakan dalam hal ini juga dihasilkan dari berbagai literatur-literatur tentang sampah seperti halnya 1).Sampah rumah tangga, 2).Pencemaran lingkungan, 3)Aktivitas manusia. Dari 12 artikel yang sudah di baca dengan baik serta teliti dari abstraknya sampai dengan simpulan, agar informasi mengenai sampah dapat kita ketahui dan kita cermati mampu memberikan arahan untuk artikel ini. Hal seperti ini merupakan tindakan yang tidak terpuji sebenarnya, maka demikian kita sebagai manusia, makhluk sosial sudah seharusnya untuk bergotong royong. Dalam hal tersebut bertujuan untuk kesadaran masyarakat akan hidup bersih perlu ditingkatkan dengan mengelola sampah untuk kepentingan pelestarian lingkungan, membiasakan membuang sampah. Sebagai manusia yang berkebutuhan selalu dengan lingkungan, kita harus melakukan segala yang kita bisa untuk mencapai tujuan masyarakat yang peduli terhadap kebersihan dan lingkungan. Dan hasil dari artikel ini untuk mengurangi pencemaran terhadap lingkungan akibat sampah rumah tangga.
Counting on COVID-19 vaccine: Insights into the current strategies, progress and future challenges
Authors: Kandimalla Ramesh , Chakraborthy Pratik , Vallamkondu Jayalakshmi , Chaudhary Anupama , Samanta Sonalinandini , Reddy P. Hemachandra , De Feo Vincenzo , Dewanjee Saikat
Published: September 2021

Emergence of a novel coronavirus viz., severe acute respiratory syndrome coronavirus (SARS-CoV-2) in late 2019 and its subsequent substantial spread, produced coronavirus disease 2019 (COVID-19) pandemic worldwide. Given its unprecedented infectivity and pathogenicity, COVID-19 pandemic had a devastating impact on human health and its clinical management. It led to development and speedy trials of several vaccine candidates against SARS-CoV-2 at an exceptional pace; as a result, several COVID-19 vaccines were made commercially available in the 2021 first half. Although, several COVID-19 vaccines showed promising results, crucial in-sights into their epidemiology, protective mechanism and propensity of reinfection are not largely reviewed. In the present report, we provided insights into the prospects of vaccination against COVID-19 and assessed diverse vaccination strategies including DNA, mRNA, protein subunits, vector-based, live attenuated, and inactivated whole/viral particle-based vaccines, imi-tating COVID-19 infection. Next, we reviewed major aspects of various available vaccines ap-proved by the WHO and by local administration to use against COVID-19. Moreover, we com-prehensively assessed the success of these approved vaccines and also their untoward effects in-cluding the possibility of reinfection. We also provided an update on the vaccines that are under development and could be the promising candidate. Conclusively, we provided insights into the COVID-19 vaccine epidemiology, their potency and propensity for SARS-CoV-2 reinfection, while a careful review of their current status, strategies, success and future challenges was also presented.
THE ROLE OF THE US NAVY BLACK SEA FLOTILLA IN THE BOMBARDMENT OF SAMSUN BY THE GREEK NAVY IN 1922
Authors: Tulun Teoman Ertuğrul
Published: September 2021

The passage of US warships from the Turkish Straits to the Black Sea has been frequently discussed in the media and the public. Recent news regarding the additional military deployments made in Greece through the Alexandroupoli port has increased interest in this issue. According to announcement made by the US Defense Visual Information Distribution Service (DVIDS), more than 300 pieces of equipment, including 10 helicopters, were offloaded there on May 5, 2021. The Black Sea region has been brought to the top of the international agenda with the emergence of an extremely tense environment in the region. The fact that the Black Sea region was brought to the top of the international agenda with the emergence of an extremely tense environment in the region due to Russia’s annexation of Crimea and oft-repeated naval exercises by naval forces in the region remind us of the developments regarding the bombardment of some of the Turkish ports in the Black Sea by the Greek navy during the establishment period of the Republic of Turkey following the end of the First World War. In this context, Greek warships made extensive bombardments on Ereğli on the Black Sea coast on 6 June, İnebolu on 30 June, and Trabzon on 20 July in the summer of 1921.. As to Samsun, the bombardment took place in the summer of 1922.The point that draws attention in this historical event is that, at the time when the Greek navy bombarded Samsun, the destroyers belonging to the US navy were also present in the port of Samsun. According to the information provided in various publications regarding this bombardment, including academic ones, these US navy warships were Clamsen class destroyers of USS Sands (DD-243), USS, McFarland (DD-237), and USS Sturtevant (DD-240).
Literacy skills seem to fuel literacy enjoyment, rather than vice versa
Authors: van Bergen Elsje , Hart Sara Ann , Latvala Antti , Vuoksimaa Eero , Tolvanen Asko , Torppa Minna
Published: September 2021

Children who like to read and write tend to be better at it. This association is typically interpreted as enjoyment impacting engagement in literacy activities, which boosts literacy skills. We fitted direction-of-causation models to partial data of 3,690 Finnish twins aged 12. Literacy skills were rated by the twins’ teachers and literacy enjoyment by the twins themselves. A bivariate twin model showed substantial genetic influences on literacy skills (70%) and literacy enjoyment (35%). In both skills and enjoyment, shared-environmental influences explained about 20% in each. Direction-of-causation modelling showed that skills impacted enjoyment. The influence in the other direction was zero. The genetic influences on skills influenced enjoyment, via the skills--> enjoyment path. This indicates active gene-environment correlation: children with an aptitude for good literacy skills are more likely to seek out literacy activities. To a lesser extent, it was also the shared-environmental influences on children’s skills that propagated to influence children’s literacy enjoyment. Environmental influences that foster children’s literacy skills (e.g., families and schools), also foster children’s love for reading and writing. These findings underline the importance of nurturing children’s literacy skills.
Editorial: Direct and Conceptual Replication in Numerical Cognition
Authors: Cipora Krzysztof , Soltanlou Mojtaba
Published: September 2021

This is the Editorial of a Special Issue "Direct and Conceptual Replication in Numerical Cognition". Please refer to the Open Access published version of this paper available at https://doi.org/10.5964/jnc.7799