bluuebunny/crossref_metadata_2025 huggingface dataset:
Pengembangan e-LKM Berbasis Case Method untuk Meningkatkan Keterampilan Mahasiswa dalam Menyusun Instrumen Evaluasi Pembelajaran
Authors: Ervan Johan Wicaksana  , Desfaur Natalia
Published: December 2023

Melakukan evaluasi proses dan hasil belajar merupakan salah satu tugas wajib guru dalam setiap pembelajaran agar kualitas pembelajaran dapat ditingkatkan. Namun banyak calon guru yang kurang mampu untuk merancang instrument evaluasi proses dan hasil belajar yang baik dan benar. Untuk itu penelitian ini dilakukan. Tujuan dari penelitian ini yaitu untuk mengetahui validitas media pembelajaran e-LKM berbasis case method guna meningkatkan keterampilan mahasiswa dalam menyusun instrument evaluasi pembelajaran. Jenis penelitian ini adalah penelitian Research and Development. Model penelitian pengembangan yang dipilih adalah model ADDIE. Tahapan model ADDIE ini terdiri dari Analisis, Design, Development, Implementation, dan Evaluation. Subjek penelitian yaitu mahasiswa Pendidikan Biologi Universitas Jambi yang mengambil matakuliah Evaluasi Proses dan Hasil Belajar. Data yang diambil berupa data kualitatif. Instrument yang digunakan yaitu angket, dokumentasi, dan lembar validasi. Hasil penelitian terutama pada analisis angket validasi ahli materi didapatkan skor presentase yaitu 88% kategori “sangat layak” dan hasil validasi ahli media didapatkan skor presentase sebesar 80% kategori “sangat layak”. Jadi dapat disimpulkan media e-LKM berbasis case method yang dikembangkan layak dan menarik untuk dijadikan sebagai bahan ajar pada matakuliah evaluasi proses dan hasil belajar.
Pengembangan Media Pembelajaran Berbasis Android pada Materi Bangun Ruang untuk Menarik Minat Belajar Siswa Kelas V SD
Authors: Inung Diah Kurniawati  , Estuning Dewi Hapsari  , Allia Whira Setyo Putri
Published: December 2023

Materi bangun ruang tingkat Sekolah Dasar (SD) pada mata pelajaran matematika merupakan salah satu materi yang dianggap sulit. Hal tersebut dikarenakan  terdapat banyak rumus untuk menyelesaikan setiap bangun ruang. Berdasarkan permasalah masalah tersebut maka dibuatlah media pembelajaran materi bangun ruang berbasis android. Penelitian ini bertujuan untuk memudahkan siswa memahami materi bangun ruang. Metode yang digunakan adalah pengembangan yang mengacu pada model Borg&Gall yang telah dimodofikasi. Terdapat lima langkah dalam pembuatan media pembelajaran. Adapun hasil media pembelajaran yang telah dibuat divalidasi oleh beberapa ahli yang meliputi ahli media, materi, dan pengguna. Berdasarkan hasil evaluasi ahli media diperoleh tingkat ketercapaian 80%, ahli materi 81,7%, dan pengguna 82%. Berdasarkan hasil tersebut dapat disimpulkan jika media pembelajaran layak untuk digunakan.
Foto Protección, una Estrategia Terapéutica y Preventiva Contra el Foto envejecimiento y Cáncer de Piel
Authors: González Moisés Santiago , Fuentes Baez Carlos Eduardo , Sánchez Villarreal Leticia , Escobar Moreno Karla Miroslava
Published: December 2023

El cáncer cutáneo es el tipo de cáncer más frecuente a nivel mundial, se considera una enfermedad maligna altamente prevenible. La principal causa de cáncer de piel es la exposición excesiva y sin protección a los rayos ultravioleta (UV). El objetivo de ese estudio es realizar una revisión detallada acerca de cuáles son las mejores estrategias de fotoproteción y conocer si son medidas eficaces para prevenir el fotoenvejecimiento y el cáncer de piel. Se realizó una revisión sistemática de la litertura en las bases de datos  especializadas de PubMed, incluyendo artículos en inlgés y español, de máximo 5 años de antigüedad. Los resulados obtenidos muestran que las medidas de fotprotección son una medida muy efiacaz para la prevención del cáncer de piel y el fotoenvejecimiento, es importante implementar esrategias de prevención ya que con ello se ha visto que se puede reducir la incidencia de cáncer de piel.
El Veneno de Sapo de la Caña Rhinella Marina, Anura: Bufonidae Provoca Daño en el Intestino Delgado en Ratones CD1
Authors: Gallardo-Casas Carlos Ángel , González Garcia Irving Moisés , Sánchez Maldonado Hugo Alberto , Jiménez Sánchez Nayelly Gabriela , Olea Vázquez Jorge Daniel
Published: December 2023

Objetivo. Describir el daño celular que provoca el veneno de Rhinella marina en el intestino delgado en un modelo murino. Métodos. Se realizó un ensayo para determinación de la LD50, y posteriormente 16 ratones machos CD1 con un peso aproximado entre 20 y 25 gramos.  se dividieron aleatoriamente en dos grupos de 8 ratones cada uno. a) Control que recibió aceite de maíz (vehículo) vía intragástrica b) Intoxicado con 250 mg/Kg del veneno vía intragástrica, a las 74 horas se sacrificaron los animales y se obtuvo la primera parte del intestino delgado para su análisis histológico y evaluación de la lipoperoxidación. Resultados. Se observó en el grupo intoxicado a diferencia del control, un aumento de la lipoperoxidación, atrofia de las microvellosidades y leucocitosis de la submucosa. Conclusión. El veneno de sapo Rhinella marina, produce daño, inflamación y peroxidación del intestino delgado, lo cuál está relacionado con las alteraciones digestivas que se ha observado cuando algunos animales sobre todo perros y gatos lo ingieren por accidente.
LITERATURE REVIEW: PENTINGNYA EDUKASI SEKS DALAM PENCEGAHAN KEKERASAN SEKSUAL PADA ANAK
Authors: - Rini Anggraini , Athiyah Ashilah  , Lia Tri Aida Saputri  , Nabilah Qatrunnada  , Nurkartika Putri  , Purnawati
Published: December 2023

Latar belakang: pendidikan seksual pada anak masih dianggap tabu bagi sebagian besar masyarakat. Kekerasan dan penyimpangan seksual di lingkungan anak sendiri disebabkan oleh berbagai faktor, salah satunya adalah kurangnya pendidikan seks bagi anak dan masyarakat. Tujuan penelitian untuk memberikan gambaran pentingnya edukasi seks dalam pencegahan kekerasan seksual pada anak. subyek dan metode: metode penelitian yang digunakan dalam penelitian ini adalah studi literatur dengan menggunakan 18 artikel dalam rentang waktu 2018 – 2023 yang diperoleh dari PubMed dan google scholar. Hasil penelitian menunjukkan pendidikan seksual pada anak memiliki manfaat yang besar guna memberikan pengetahuan, menghindari anak dari serangan serta risiko negatif kekerasan seksual. Pemberian edukasi seks pada anak dapat dilakukan dengan bantuan tenaga pendidik, orang tua, serta tokoh agama. Media yang dapat dijadikan bahan edukasi seperti ceramah dan diskusi, mainan, buku, dan aplikasi yabg menarik. Saran kepada orang tua memberikan perhatian dan pengawasan yang cukup serta menjadi teladan yang baik saat dirumah. Selanjutnya bagi para guru untuk dapat memberikan perhatian, pengawasan, dan pembelajaran mengenai pendidikan seks disekolah.
 
Kata kunci: anak, edukasi seks, kekerasan seksual, pencegahan
 
Background: sexual education in children is still considered taboo for most people. Violence and sexual deviation in children's environment is caused by various factors, one of which is the lack of sex education for children and society. The aim of the study to provide an overview of the importance of sex education in preventing sexual violence in children. Subject and method: the method used in this research is a literature study using 18 articles in the 2018 – 2023 period obtained from PubMed and Google Scholar. The result showed that sexual education for children has great benefits in providing knowledge, preventing children from being attacked and the negative risks of sexual violence. Providing sex education to children can be done with the help of educators, parents, and religious leaders. Media that can be used as educational material such as lectures and discussions, toys, books, and interesting applications. Suggested to parents give sufficient attention and supervision and be a good role model at home. Furthermore, for teachers to be able to provide attention, supervision, and learning about sex education in schools.
 
Keywords: sex education, prevention, sexual violence, children
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN PEMANFAATAN POS PEMBINAAN TERPADU PENYAKIT TIDAK MENULAR (POSBINDU PTM) DESA MANTUYAN KECAMATAN HALONG
Authors: Irianty Hilda , Agus Jalpi  , Eka Vivi Lestari  , Khairul Anam
Published: December 2023

Latar belakang: pemanfaatan Posbindu Penyakit Tidak Menular di Desa Mantuyan masih sangat kurang. Jumlah kunjungan Posbindu penyakit tidak menular di tahun 2022 sebanyak 302 orang (40%). Sehingga sekitar 60% penduduk Desa Mantuyan belum memanfaatkan fasilitas Posbindu penyakit tidak menular. Tujuan penelitian ini untuk mengidentifikasi dan menganalisis faktor-faktor yang berhubungan dengan pemanfaatan pos pembinaan terpadu penyakit tidak menular Desa Mantuyan Kecamatan Halong. Subyek dan metode: penelitian ini bersifat kuantitatif dengan pendekatan Cross Sectional dan menggunakan uji chi-square. Sampel penelitian ini berjumlah 92 responden dengan teknik sampling Accidental Sampling. Hasil penelitian sebagian besar responden 57,6% tidak memanfaatkan Posbindu penyakit tidak menular, pengetahuan masyarakat maayoritas baik sebanyak (54,3%), sebagian besar sikap masyarakat positif sebanyak (59,8%) dan aksesbilitas masyarakat akan memanfaatkan Posbindu mayoritas jauh sebanyak (52,2%). Hasil analisis statistik disimpulkan bahwa ada hubungan yang signifikan antara pengetahuan (p=0,002), sikap (p= 0,026) dan aksesbilitas (p=0,041) dengan pemanfaatan pos pembinaan terpadu penyakit tidak menular.
 
Kata Kunci: aksesibilitas, pengetahuan, penyakit tidak menular, posbindu, sikap
 
Background: the use of non-infectious diseases in the village of Mantuyan is still very low.The number of visits after non-contagious diseases in 2022 was 302 people (40%).So about 60 percent of the village population have not been using the post-sensitive facilities for non-sensitive diseases. The purpose of this research is to identify and analyze factors related to the utilization of the united breeding post the disease does not infect the fishing village Halong obscenity. This method of research is categorical with the cross sectional approach and using the chi-square test. This research sample has a total of 92 responders with sampling accidental sampling techniques. Research results mostly responders 57.6 % do not utilize non-infected disease posbindu, good public knowledge (54.3 %), most of society's positive attitudes (59.8 %) and people's accessibility will take advantage of the vast majority ( 52.2 %). From the statistics concluded that a significant relation exists between variables knowledge (p=0,002)attitude (p= 0,026) and accessibility (p = 0,041 ) post integrated development in terms of non-infectious disease.
 
Keywords: attitude, accessibility, knowledge, non-infectious disease, posbindu
ANALISIS PENERAPAN ALAT PEMADAM API RINGAN (APAR) DAN JALUR EVAKUASI DALAM UPAYA MENCEGAH KEBAKARAN DI RSUD KOTA KENDARI TAHUN 2022
Authors: Arianti Dina , Yuniar Nani , Jafriati Jafriati
Published: December 2023

Kebakaran dapat terjadi diberbagai tempat, antara lain perumahan mewah, perumahan kumuh, hotel, perkantoran, kereta api, mall, hutan belantara, bahkan perusahaan besar yang telah menerapkan sistem manajemen kebakaran. Rumah sakit sebagai wadah bekerja tenaga kesehatan dan merawat pasien juga tidak lepas dari resiko kebakaran. Tujuan Penelitian ini yaitu untuk mengetahui penerapan Alat Pemadam Api Ringan (APAR) Dan Jalur Evakuasi Dalam Upaya mencegah Kebakaran Di RSUD Kota Kendari Tahun 2022. Jenis penelitian yang digunakan adalah kualitatif dengan pendekatan fenomenologi. Informan dalam penelitian ini berjumlah 4 orang, yaitu kepala komite K3, Bidang Kebakaran, Bidang Evakuasi, dan penanggung jawab APAR. Penentuan informan menggunakan teknik purposive sampling. Instrument yang digunakan adalah pedoman wawancara, lembar observasi dan dokumentasi. Analisis data menggunakan rumus persentase dari nilai perbandingan jumlah APAR yang sesuai dengan keseluruhan jumlah APAR yang ada. Hasil Penelitian menunjukkan bahwa APAR yang harus ditempatkan pada posisi yang jelas 96,2% sudah sesuai, dilengkapi tanda pemasangan 88,8% sesuai, tabung masih berisi dan memiliki tekanan 98,1% sesuai, tinggi pemberian tanda pemasangan APAR 100% tidak sesuai dan jarak antara APAR satu dan yang lainnya 100% tidak sesuai. Untuk ketersediaan jalur evakuasi seperti titik kumpul dan tangga darurat sudah sesuai, sedangkan untuk pintu darurat belum sesuai dengan standar. Simpulan penelitian Penerapan Alat Pemadam Api Ringan (APAR) sudah sesuai dengan standar PERMENAKERTRANS No.PER.04/MEN/1980 kemudian ketersediaan Jalur evakuasi, titik kumpul, dan tangga darurat untuk pintu darurat belum sesuai dengan standar SNI 03-1746-2000.

Kata kunci: APAR, jalur evakuasi, kebakaran, rumah sakit
FAKTOR YANG BERHUBUNGAN DENGAN KECELAKAAN LALU LINTAS DI WILAYAH SATUAN LALU LINTAS POLRES KOTA KENDARI TAHUN 2022
Authors: Hesti Hesti , Sety La Ode Muhamad , Tosepu Ramadhan
Published: December 2023

Kecelakaan lalu lintas tidak dapat dipandang sebagai persoalan transportasi semata tetapi sudah merambat menjadi masalah kesehatan. Kota Kendari merupakan salah satu kota di Provinsi Sulawesi Tenggara dengan persentase kejadian kecelakaan lalu lintas yang cukup tinggi. Dampak negatif yang didapatkan dari kecelakaan lalu lintas dapat mempengaruhi derajat kesehatan masyarakat. Penelitian ini bertujuan untuk mengetahui faktor yang berhubungan dengan kecelakaan lalu lintas di wilayah satuan lalu lintas Polres Kota Kendari Tahun 2022. Jenis penelitian yang digunakan adalah penelitian observasional analitik dengan pendekatan cross-sectional. Jumlah sampel dalam penelitian ini adalah 174 kejadian kecelakaan dengan teknik pengambilan sampel menggunakan simple random sampling. Analisis data meliputi univariat dan bivariat dengan menggunakan uji chi-square/fisher exact. Hasil penelitian menunjukkan bahwa tidak ada hubungan antara faktor kondisi pengemudi dengan kejadian kecelakaan lalu lintas (pvalue = 1,000). Faktor jenis kendaraan ada hubungan dengan kejadian kecelakaan lalu lintas (pvalue = 0,004). Tidak ada hubungan antara faktor cuaca dengan kejadian kecelakaan lalu lintas (pvalue = 1,000). Faktor kondisi jalan tidak ada hubungan dengan kejadian kecelakaan lalu lintas (pvalue = 1,000). Kesimpulan, ada hubungan antara jenis kendaraan dengan kecelakaan lalu lintas di wilayah satuan lalu lintas Polres Kota Kendari tahun 2022. Tidak ada hubungan antara kondisi pengemudi, cuaca, dan faktor kondisi jalan dengan kecelakaan lalu lintas di wilayah satuan lalu lintas Polres Kota Kendari tahun 2022.

Kata kunci: agent, environment, host, kecelakaan lalu lintas
Sistem Manajemen Aset Tetap Berbasis Web untuk Memudahkan Manajerial Data Pada Politeknik Pelayaran Banten (POLTEKPEL Banten)
Authors: Ikka Ikka , Sidik Achmad , Triono Triono
Published: December 2023

Aset tetap adalah suatu hal yang sangat dijaga oleh Politeknik dan digunakan dalam operasionalnya. Dengan jumlah aset yang besar, diperlukan manajemen yang efisien untuk mengelolanya. Itulah sebabnya, Politeknik perlu sistem yang dapat menjaga dan dapat mengelola asset tetap secara baik, agar dapat menjadikan informasi yang tepat, akurat serta cepat oleh manajemen Politeknik. Penelitian ini bertujuan untuk menganalisis dan merancang sistem informasi manajemen aset yang digunakan oleh Politeknik Pelayaran Banten (Poltekpel Banten), dengan tujuan menentukan kebutuhan sistem yang dibutuhkan oleh Politeknik tersebut. Selanjutnya, akan dirancang dan dibangun sebuah sistem informasi dengan basis data yang sesuai dengan kebutuhan manajemen aset Politeknik, menggunakan basis data MySQL. Sistem ini diharapkan dapat membantu menyederhanakan dan mempercepat proses pengumpulan informasi terkait aset, termasuk pencatatan, pemeliharaan, penghapusan, serta penyusutan dari asset tetap tersebut. Sistem informasi manajemen aset ini dikembangkan menggunakan metode Software Development Life Cycle (SDLC), dengan pendekatan yang melibatkan pengumpulan data, analisis, dan desain dari penelitian sebelumnya. Hasil yang didapat dari penelitian ini yaitu sebuah sistem informasi manajemen asset tetap berbasis website yang diharapkan dapat membantu Politeknik Pelayaran Banten (Poltekpel Banten) dalam mengelola aset Politekniknya dengan lebih baik.
Integritas dalam Transaksi menggunakan Sistem Pembayaran SPP Berbasis Web pada SMK Az Zahra sepatan
Authors: Soetjipto Ken Sabardiman , Iqbal Muchamad , Rika Rika , Rachmadi Basuki
Published: December 2023

SMK Az zahra Sepatan merupakan bagian dari yayasan pendidikan wagimin center.Sistem informasi yang berjalan di SMK Az zahra Sepatan khususnya pada Pembayaran Sumbangan Pembinaan Pendidikan (SPP) masih menggunakan sistem secara manual dan belum terkomputerisasi, Sehingga memperlambat pelayanan terhadap siswa, dan keamanan datanya pun masih kurang dan dapat menimbulkan kehilangan data dan juga saat pembuatan laporan akan mengalami kesulitan. Maka dari itu, perlu dibangun sistem pembayaran spp yang terkomputerisasi hal ini bertujuan agar pelayanan pembayaran SPP lebih efektif dan efisien dan sistem ini juga sebagai media penghubung antara orangtua siswa dengan pihak sekolah dalam mengecek pembayaran yang telah dilakukan oleh putra putrinya. Metode pengumpulan data pada penelitian ini menggunakan metode observasi, wawancara dan studi pustaka, dan untuk perancangan menggunakan metode Oriented Object Analysis Design (OOAD) dan menggunakan Unified Modeling Language (UML). Sistem ini dibangun menggunakan bahasa pemograman PHP dan MYSQL sebagai databasenya. Hasil dari penelitian ini bahwa sistem pembayaran spp ini sangat mudah digunakan dan dapat membantu staf tata usaha dalam melakukan proses pembayaran spp dan orangtua pun dapat mengakses sistem ini namun,hanya dapat melihat status pembayarannya saja.
E-Commerce Furniture untuk Memperluas Pemasaran serta Efektifitas Penjualan Pada CV. Revan Interior
Authors: Oetario Putro R. Andy , Sunggono Nova Teguh , Saputro Irfan Arif
Published: December 2023

E-commerce adalah kegiatan jual beli barang dan jasa melalui penggunaan website dan internet yang biasanya sering disebut business to consumer, yang menjadi suatu alat transaksi digital untuk memudahkan penggunanya. Aplikasi ini memudahkan orang untuk berbelanja, hanya dengan komputer dan jaringan internet semua orang dapat berbelanja dengan mudah. Prosesnya pun cukup singkat dan tidak merepotkan. Untuk pembayaran barang yang dibeli, pembeli dapat membayar dengan cara mentranfer pada bank yang telah ditentukan, maka barang yang dibeli bisa dikirim. Dalam pembuatan website e-commerce ini penulis mengunakan bahasa pemrograman PHP. Perancangan sistem ini, penulis menggunakan metode black box untuk proses testing guna memastikan tidak terjadi error pada saat digunakan. Perancangan sistem ini menggunakan metode SDLC (System Development Life Cycle) untuk pengembangan sistem yang mendefinisikan perkiraan kebutuhan-kebutuhan sumber daya pada sebuah sistem aplikasi. Perancangan aplikasi berbasis website ini digunakan untuk pengelolaan pemesanan furniture pada CV.Revan Interior. Dari uji sistem yang dilakukan, diperoleh hasil bahwa sistem ini sangat membantu pemasaran produk usaha kecil menengah.
Afrotropical Atrichops Verrall (Diptera, Athericidae) with description of a new species
Authors: Muller Burgert S. , Swart Vaughn R. , Snyman Louwrens P.
Published: December 2023

Atrichops Verrall, 1909 of the Afrotropical Region are revised, and Atherix adamastor Stuckenberg, 1960, previously unplaced, is transferred to Atrichops based on morphological characters and feeding ecology. A new South African species, A. intermediussp. nov. is also described from Mpumalanga Province.
Facile, sensitive and reagent-saving smartphone-based digital image colorimetric assay of captopril tablets enabled by long-pathlength RGB acquisition
Authors: Thanayutsiri Thana , Charoenying Thapakorn , Patrojanasophon Prasopchai , Pamornpathomkul Boonnada , Opanasopit Praneet , Ngawhirunpat Tanasait , Rojanarata Theerasak
Published: December 2023

A new assay of captopril (CTP) tablets was developed based on digital image colorimetry using Ellman’s reagent. For the first time, a facile technique of increasing the analytical path was applied in this work to enhance the sensitivity. For this purpose, the reaction solutions were photographed using a smartphone while they were contained in two 1-cm pathlength cuvettes which were placed side by side. The Red-Green-Blue (RGB) in term of [B/(R+G+B)] was used to plot a standard curve. Compared to using a single cuvette, double cuvettes resulted in more precise analytical signals and better linearity (r2 of 0.9992). Additionally, CTP could be analyzed at low concentrations (2.5–25 µM) with LOD of 0.70 µM and LOQ of 2.13 µM, thus lowering the reagent consumption. The assay was proven to be valid, and it was greener, faster, and more affordable than the pharmacopeial chromatographic method, thereby suitable for pharmaceutical quality control.
A new bamboo-feeding species of the genus Pseudosymplanella Che, Zhang & Webb, 2009 (Hemiptera, Caliscelidae, Ommatidiotinae) from China
Authors: Gong Nian , Chen Xiang-Sheng , Yang Lin
Published: December 2023

A new planthopper species,Pseudosymplanella maximasp. nov., belonging to the genusPseudosymplanella(Hemiptera: Fulgoromorpha: Caliscelidae: Augilini), is described and illustrated, from China. In common with other Chinese Augilini, the new species feeds exclusively on bamboo. Additionally, a key to the two species ofPseudosymplanellais provided.
Surmonter la crise en Centrafrique
Authors: de Clermont Jean-Arnold
Published: December 2023

La crise politique qu’a vécue la Centrafrique en 2013 invite à analyser la situation complexe de ce pays. Plusieurs causes, internes (mauvaise gouvernance) et externes (interventions de pays étrangers), alimentent la violence. La composante religieuse est à prendre en compte dans ce pays multiconfessionnel. Il y a encore fort à faire pour assurer une paix durable.
Nostalgie républicaine ou refondation ?
Authors: Thibaud Paul
Published: December 2023

Les événements du début janvier en France questionnent le rapport entre religion et politique, au-delà de l’intégration de l’islam dans un régime de laïcité. Il en va de la refondation de l’idée de civisme et d’une meilleure dialectique entre ces deux instances. S’ils jouent le jeu de l’ouverture, les chrétiens peuvent apporter une contribution significative.
Des bienfaits de la vie conjugale
Authors: Moreau Denis
Published: December 2023

Pendant longtemps, le mariage a plus été une affaire de raison que d’amour. La fragilisation actuelle du lien conjugal ravive le questionnement : un engagement amoureux dans la durée est-il possible ? En s’appuyant sur son expérience, un philosophe s’interroge sur les bienfaits de la vie conjugale.
La résurrection, une mission de paroles
Authors: Sèbe Jean-Baptiste
Published: December 2023

La publication du livre d’Emmanuel Carrère Le Royaume a mis en avant l’enquête-parcours d’un écrivain qui s’intéresse au christianisme mais déclare – c’est son droit le plus strict – ne pas croire à la résurrection. Au-delà des débats suscités par son ouvrage-fleuve, le cœur de la foi chrétienne, la résurrection fait toujours face à autant de questions. Comment la littérature contemporaine peut-elle ouvrir de nouvelles perspectives au théologien ?
Daniel Arasse et Georges Bernanos
Authors: Asensio Juan
Published: December 2023

Il pourrait sembler loufoque de rapprocher le grand historien de la peinture que fut Daniel Arasse de Georges Bernanos. Pourtant l’un et l’autre ont su nous réapprendre à voir les derniers signes du sacré, divin ou maléfique.
Être chez soi, être soi
Authors: Zielinski Agata
Published: December 2023

Une écrasante majorité de Français souhaite finir sa vie à domicile plutôt qu’à l’hôpital. Cela invite à s’interroger sur le « chez soi ». Comment demeurer soi-même quand surgit l’épreuve de la dépendance ? Comment articuler vulnérabilité et autonomie, sinon dans une dynamique relationnelle sensible aux capacités (ou aux « capabilités ») de la personne ?
Stages d’internat en PMI : regards croisés des médecins généralistes, PMI et facultés
Authors: Geant Marie-Alice , Bois Corinne
Published: December 2023

Introduction : Les médecins généralistes jouent un rôle essentiel dans la prise en charge médicale des enfants en France. Les services de Protection Maternelle et Infantile (PMI) déclinent des soins pédiatriques de prévention et accueillent en stage des internes médecins généralistes (MG). L’objectif de ce travail est de croiser les regards des parties prenantes des stages PMI. Méthode : Nous avons conduit une étude transversale déclarative en France métropolitaine en 2019 auprès des MG, PMI et départements de médecine générale des facultés (DMG) et recueilli des données sur l’organisation, le contenu et les attendus pédiatriques du stage pour les MG en PMI. Résultats : Les réponses de 286 MG, 77 PMI et 16 DMG ont été collectées. Les MG décrivent une pratique de stage non standardisée pour la durée, le type de supervision, les actes réalisés et les outils mis à disposition. Leurs réponses dégagent pourtant un consensus net sur l’acquisition de compétences (significativement supérieures pour les stages de 4 jours hebdomadaires) concernant le dépistage et la prévention ; le soutien à parentalité ; la découverte de l’environnement de l’enfant et des autres professionnels du champ sanitaire, psychologique et éducatif. Ces acquisitions sont partielles en protection de l’enfance, et insuffisantes pour la prise en charge des pathologies aigües. Les liens entre DMG et PMI apparaissent médiocres. Conclusion : Les stages en PMI apportent aux MG une expérience importante en prévention et pédiatrie du quotidien, mais nécessitent une meilleure concertation entre DMG et PMI, et la construction de stages mixtes notamment avec la pédiatrie hospitalière.
Triage des patients et consultations à distance dans les structures de soins primaires pendant la pandémie de Covid-19 en France (étude PRICOV-19)
Authors: Viegas Laura , Dupie Isabelle , Rigal Laurent , Van Poel Esther , Willems Sara , Beaupin Alain , Falcoff Hector
Published: December 2023

Introduction : PRICOV-19 est une étude transversale européenne basée sur un questionnaire en ligne, décrivant l’impact de la pandémie sur les structures de soins primaires (SSP). En France, les SSP sont les cabinets solo (CS), les cabinets de groupe mono ou pluriprofessionnels (CG), les structures d’exercice coordonné (SEC) : maisons de santé et centres de santé. Le triage, qu’il soit numérique (TN), téléphonique (TT) ou à l’arrivée (TA) est indispensable pour réduire le risque infectieux, et fait partie des pratiques d’organisation recommandées. But de l’étude : En s’appuyant sur les données françaises de l’étude PRICOV-19, l’objectif est de décrire la fréquence et les facteurs associés au triage dans les SSP pendant la pandémie de COVID 19. Résultats : 1 100 structures ont répondu au questionnaire. Le TN a été mis en œuvre dans 64 % des SSP (53,3 % des CS, 64,9 % des CG, 73,2 % des SEC). Le TT a été mis en œuvre dans 76 % des structures (72,7 % des CS, 75,4 % des CG et 81 % des SEC). Enfin, le TA a été mis en œuvre dans 52 % des structures (37,7 % des CS, 52 % des CG et 67 % des SEC). Les autres facteurs positivement associés sont le territoire urbain et la charge de travail moins importante pour le TN, et la présence d’une réceptionniste pour le TA. Conclusion : Les pratiques de triage semblent clairement associés à l’organisation et aux conditions d’exercice dans les SSP, et en premier lieu au type de structure.
György Ligeti Études pour piano
Authors: Boukobza Jean-François
Published: December 2023

Les trois cahiers d’Études pour piano de György Ligeti - 18 pièces composées entre 1985 et 2001 - constituent un monument de l’écriture moderne pour le piano. Elles s’appuient aussi bien sur la grande littérature pianistique (Scarlatti, Chopin, Debussy…), ou le jazz et le piano mécanique de Nancarrow, que sur les musiques balkaniques, africaines, asiatiques ou caribéennes, sur diverses théories physiques et mathématiques que sur des sources visuelles qui vont de Jérôme Bosch à Maurits Escher.Le livre de Jean-François Boukobza, le premier consacré à ce corpus, dévoile ces sources multiples et présente chaque étude en détail, faisant apparaître leurs principes d’organisation, leur poétique, leurs répercussions et la manière de les approcher pour l’interprète.Un entretien avec Pierre-Laurent Aimard conclut l’ouvrage.
Comparison of P300 Cognitive-evoked Potentials and Visual and Auditory Reaction Time in Stage 5 Chronic Kidney Disease Patients on Different Treatment Modalities
Authors: Renugasundari Manoharan , Velkumary Subramaniyam , Parameswaran Sreejith , Nanda Nivedita , Fredrick Jean
Published: December 2023

Patients with chronic kidney disease (CKD) are at a higher risk of cognitive impairment. Poor quality of life and decreased compliance are frequently observed with cognitive decline among CKD patients. Cognitive impairment among Stage 5 CKD patients varies with different modalities of treatment, and contradicting results have been reported. Fifty-four medically stable Stage 5 CKD patients undergoing different modalities of treatment were recruited: Patients with Stage 5 CKD on maintenance hemodialysis (HD) (n= 18), continuous ambulatory peritoneal dialysis (CAPD) (n= 18), and conservative management (CM) (n= 18). Eighteen apparently healthy participants were recruited as a control group. The cognitive functions assessed were P300 event- related potential, auditory and visual reaction times (VRTs). Kidney function was assessed by serum creatinine and estimated glomerular filtration rate. Creatinine levels were significantly higher in all three treatment groups compared with the control group. Multivariate analysis revealed a significant association between the CKD groups (n= 54) and the parameters of cognitive function. P300 latency was prolonged in all treatment groups compared with the control group and was significantly prolonged in patients on CM compared with HD and CAPD patients. The VRT of CM patients was found to be significantly higher compared with the control group. The auditory reaction time was significantly prolonged in all treatment groups compared with the control group and in the CM group compared with the CAPD group. Cognitive function was more affected in Stage 5 CKD patients on CM compared with patients undergoing HD or CAPD.
Essentials of Computed Tomography Imaging of Hematuria
Authors: Patel Vaidehi A. , Popat Nidhi P.
Published: December 2023

Hematuria is defined usually as the presence of blood in the urine, either on voiding or in a catheterized specimen. Hematuria is broadly divided into microscopic and gross hematuria and may be symptomatic or asymptomatic. The causes of hematuria include a very wide spectrum of conditions. However, here, we have filtered the causes causing gross hematuria, including calculus, trauma, tumors, vascular, and miscellaneous causes. Plain X-rays of the kidney, ureter, and bladder; ultrasound; intravenous urography; computed tomography (CT); magnetic resonance imaging; retrograde ureterography and pyelography (RGP); cystoscopy; and ureteroscopy are techniques that are useful for diagnosis. In the past, one or a combination of several techniques was used to evaluate hematuria but recently, advances in CT urography mean that it can be used alone for this task. This article briefly reviews the common causes of gross hematuria in adults and their evaluation by CT-based urography. Gross hematuria is evaluated well with CT scan urography which includes an unenhanced scan, the nephrographic phase, and the excretory phase. Unenhanced scans are routinely performed to evaluate the basic parameters such as the size, shape, position, and outline of the kidneys and calculus disease, which is the most common cause of hematuria. Renal parenchymal diseases including masses are best visualized in the nephrographic phase along with other abdominal organs. Delayed excretory phases including the kidneys, ureters, and bladder are useful for detecting urothelial diseases. CT urography's protocol permits evaluations of hematuria through a single examination.
Comparative Evaluation of Microbial Contamination on the Mobile Phones Used by Dental Health-care Professionals versus Faculty of School System
Authors: Arora Pooja , Arora Deepak , Singla Ruby , Mitruka Bindu
Published: December 2023

Introduction:

Mobile phones are frequently used in environments of high bacteria presence. These can harbor various potential pathogens and become an exogenous source of nosocomial infections. Even in recent outbreak of COVID-19, it has become a point which needs to be sanitized to prevent and control further disease transmission as it is equally important for health-care professionals to use mobile phones in the hospital and other health and care settings, especially for communication. The present study was conducted to determine the potential role of mobile phones in the dissemination of disease.

Objective:

To compare the evaluation of microbial contamination on the mobile phones used by dental health-care professionals and faculty of senior secondary school and to access the microbial contamination of mobile phones by measuring the percentages of pathogens and to determine the type of bacteria commonly present on mobile phones. It also assesses the efficacy of 70% ethyl alcohol to be used as decontamination solution.

Materials and Methods:

A total of 126 mobile phones were screened in the study; 63 mobile phones belonging to dental health-care personnel from nine different specialties of dental college (Group 1 – test group) and 63 mobile phones belonging to nonhealth-care personnel like school teachers of senior schools (Group 2 – control group). All the samples were taken before and after cleaning with 70% ethyl alcohol. A total of 252 swab samples were taken.

Results:

Microbial contamination was approximately 68% in swab samples taken from mobile phones before cleaning with 70% of ethyl alcohol but even with one time disinfection with alcohol, decontamination was found to be only 95% effective. Coagulase-negative Staphylococcus was the most common isolated organism in swabs collected from dental college. Pathogenic bacteria were more prevalent in samples of dental college than to school samples.

Conclusion:

Ninetythree percentage of cell phones of health-care workers were contaminated and they act as potential source of nosocomial infections. Alcohol should be used to disinfect the mobile phones.
Role of methylene blue dye in sentinel node biopsy in N0 oral cavity squamous cell carcinoma
Authors: Upadhyay Kiran , Gupta Vikas , Sahu Pankaj K. , Basu Abhijit , Bhatia Ritika
Published: December 2023

Background:

Presence of neck nodes in cases of head neck squamous cell cancers is an adverse prognostic factor. Elective neck dissection is traditionally recommended along with primary disease resection. Sentinel lymph node (SLN) is the first draining node. Sentinel lymph node biopsy (SNB) is a minimally invasive technique to identify occult nodal metastasis in early HNSCC.

Methods:

The objective of this study is to determine the identification rate of SNB using methylene blue dye (MBD) in N0 neck of Oral Squamous cell carcinoma (OSCC) and estimating specificity, sensitivity, negative predictive value and positive predictive value of SNB with frozen section (FS) analysis and in comparison to post-operative histopathological examination (HPE). It is a cross-sectional study conducted at a tertiary care centre, Lucknow, India. 21 patients of N0 OSCC from January 2019 to May 2020, were included. All patients underwent peritumoral injection with MBD. Sentinel nodes were harvested and sent for FS. Depending on FS findings, appropriate neck dissection was performed.

Results:

SLN was identified at level Ib and II in 19 patients (90.47%). The sensitivity, specificity, PPV and NPV in identifying SLN using MBD versus FS were 100.00%, 11.11%, 15.79% and 100.00% respectively. Whereas, SLN using MBD versus HPE specimens were 100.00%, 10.52%, 10.52% and 100.00% respectively.

Conclusion:

Despite having 100% sensitivity, MBD alone has poor specificity. With this poor discriminatory power, it is unlikely to be employed as a diagnostic test alone. It is recommended to rely on per-operative FS for taking decision as far as extent of neck dissection in N0 neck is concerned.
A Review on Alternative Methods to Experimental Animals in Biological Testing: Recent Advancement and Current Strategies
Authors: Husain Asif , Meenakshi Dhanalekshmi U. , Ahmad Aftab , Shrivastava Neelima , Khan Shah A.
Published: December 2023

With an increase in the progression of research and development in the medical field, the experimental use of animals for the efficacy and safety testing of pharmaceuticals is on rise. Every year, millions of animals are used for experimental testing during which these suffer from pain and are then eventually sacrificed. Besides bioethical issues, animal experimentation is associated with many disadvantages like high cost, the requirement of skilled manpower, approval, and is time-consuming. Therefore, attempts have been made by researchers to design and develop a number of alternative methods that could bypass animal experiments. These methods not only give accurate results but can also save lives of millions of animals annually. Research techniques, including computer and robotics together with molecular biology techniques, are applied to discover new methods to replace animal testing. Several alternative methods are discussed in this review. Some of these methods can predict the behavior of drugs accurately and are as reliable as in-vivo animal models. Furthermore, these alternative methods offer a variety of advantages over experimental animals. However, there is still a great need to discover and develop new, accurate, and reliable methods to replace experimental animals.
Silver Nanoparticles from Saudi and Syrian Black Cumin Seed Extracts: Green Synthesis, ADME, Toxicity, Comparative Research, and Biological Appraisal
Authors: Rashid Mohammad , Athar Md Tanwir , Abdelmageed Mohammed , Al-Harbi Mohammed Hilal M , Husain Asif , Bisht Dheeraj , Arya Rajeshwar Kamal Kant
Published: December 2023

Objective:

The current study’s objective is to highlight the value of using plant resources to identify key bioactive molecules and implement green chemistry in research and development to meet market demand.

Materials and Methods:

The black cumin seeds (Saudi and Syria originated) were utilized to make silver nanoparticles (Ag-NPs), which were subsequently confirmed using a UV spectrophotometer and color analysis of reaction mixtures. The antibacterial activity of Ag-NPs was tested against E. coli, K. pneumoniae, and S. aureus, and antioxidant activity was measured using the DPPH assay. Swiss-ADME, pkCSM, and ProTox-II were also used to assess the pharmacokinetics, oral bioavailability, toxicity, and safety endpoints of molecules.

Result:

The antibacterial effect of Ag-NPs from Saudi-origin black cumin seeds was observed higher. In comparison to the standard, the Saudi and Syrian Ag-NPs combined displayed synergistic antibacterial effects and were found to be more susceptible to S. aureus. In comparison to the reference, the antioxidant activity of Ag-NPs indicated 60–85% radical scavenging. All molecules passed the Lipinski rule, the filter (Veber, Egan, and Muegge), PAINS, and the Brenk structural alert (zero violations), and the synthetic score was also found to be in the easy limit (1 to 2). The compounds were found to be non-substrate for p-glycoprotein, high GIA% (>90%), non-inhibitor for CYP3A4, CYP2C19, CYP2C9, CYP2D6 (except 5 and 10), Log Po/w (1.71 to 3.26), TPSA 150 2 and MR 155. The compounds likewise had high Caco2 values (log Papp >0.9) with the exception of 4 and 9 (log Papp 0.9), were non-inhibitors of P-gp-I and II and hERG I and II, and showed no AMES toxicity. Except for molecule 11, no organ damage (hepatotoxicity) or endpoint toxicity (mutagenicity, immunotoxicity, carcinogenicity, and cytotoxicity) was identified in ProTox-II.

Conclusion:

The current study sheds new light on the significance of bioactive molecules found in black cumin seeds, with molecules 3 and 6 identified as potential leads (highest GIA%, no AMES toxicity, oral rat acute and chronic toxicity, lack of renal OCT2 substrate, high total clearance, and lack of organ toxicity) for further research for a variety of medical applications.
Reliability and usefulness of YouTube as a source of informative media for arthroscopic tennis elbow surgery: A systematic review of the published videos
Authors: Choudhury Arghya Kundu , Bansal Shivam , Raja Balgovind S. , Paul Souvik , Chaubey Sachin , Kalia Roop Bhushan
Published: December 2023

Aims and Objectives:

Over the last decade, YouTube has been extensively used as a learning tool for both physicians and patients, but the reliability of this information remains questionable. The purpose of this study was to look for the reliability and quality of videos on tennis elbow arthroscopy on YouTube.

Materials and Methods:

We used three search terms on YouTube “tennis elbow arthroscopic surgery,” “Arthroscopic ECRB release,” and “Arthroscopic debridement for tennis elbow,” and screened the first 50 videos according to popularity. The videos were included from 2009 to date. Only videos in the English language were included. Repeated videos and videos without sound were excluded. A total of 74 videos were selected for this study and reliability was checked with DISCERN and journal of the American medical association (JAMA) scores. The quality was assessed with the Global Quality Score Criteria (GQSC) score and TEARS (a novel score). Popularity was tested with the video power index (VPI). A pilot study was conducted using 20 videos to validate the TEARS score.

Results:

In the pilot study, TEARS showed results in accordance with other scores used. The average number of views was 41,644.97, and the average duration was 5.03 ± 3.39 years. The mean value of DISCERN and JAMA was found to be 21.47 ± 6.28 and 1.05 ± 0.92, respectively. GQSC, TEARS, and VPI were found to be 1.70 ± 0.82, 4.17 ± 2.62, and 769,936.9 ± 6,538,851.37.

Conclusion:

Most of the videos were educational and physicians were targeted. The USA was the major contributor to such videos. The reliability and quality of these videos were found to be of poor quality. The video popularity was however found to be relatively high. The inter-observer reliability was good. Based on the findings, we conclude that the videos are not reliable and could not be used for learning.
The impact of COVID-19 pandemic on the pattern and presentation of traumatic dental injuries in children in a tertiary health institution
Authors: Eigbobo Joyceln Odegua , Raymond Stanley Chukwunonso , Nzomiwu Chioma Love , Okolo Nkiru Ifeyinwa , Okonkwo Etaphromare
Published: December 2023

Background:

COVID-19 pandemic brought adaptive changes in lifestyle with possible impact on the incidence of traumatic dental injuries.

Objective:

This study compared the presentation and pattern of traumatic dental injuries in children during the pre-COVID-19 and COVID-19 pandemic periods.

Materials and Methods:

This was a retrospective study done using clinical records of children aged 16 years and below who presented at the paediatric dental clinic of the University of Port Harcourt Teaching Hospital. Information such as demographics, aetiology, type of injuries, and dentition type were elicited from the 1284 clinical records from March 2019 to February 2021. Data were analysed and the level of significance was set at P ≤ 0.05.

Result:

One hundred (7.8%) patients presented with traumatic dental injuries (TDIs; 71 [8.5%] and 29 [6.5%] pre-pandemic [March 2019 to February 2020] and pandemic periods [March 2020 to February 2021], respectively) and their mean age was 7.0 (±4.2) years. The male-to-female ratio before and during the pandemic periods was 1.54:1 and 1.42:1, respectively. The commonest aetiology and type of TDI were falls 82 (82%) and injuries to tooth-supporting structures 45 (45%), respectively. There were no statistically significant differences in sex (P = 0.86), aetiology (P = 0.31), type of TDI (P = 0.16), and dentition affected (P = 0.97) between the pre-pandemic and pandemic periods but the difference in the age groups was significant (P = 0.02).

Conclusion:

The incidence of TDIs was higher in the pre-pandemic period. The younger age group had more dental injuries than the older ones at both periods. This may be due to difficulty in enforcing restrictions on young children even during COVID-19 restrictions.
Impact of coronavirus disease 2019 on intravitreal antivascular endothelial growth factor injection rates in Nigerians
Authors: Okonkwo Ogugua Ndubuisi , Hassan Adekunle Olubola , Bogunjoko Tayo , Akinye Ayodele , Akanbi Toyin , Agweye Chineze
Published: December 2023

Aim:

To quantify the impact of coronavirus disease 2019 (COVID-19) on the rate of intravitreal antivascular endothelial growth factor (VEGF) injections (IVI) in eye hospitals in Nigeria.

Materials and Methods:

A retrospective, observational, comparative study. The IVIs given 12 months before (pre-COVID) and 12 months after the first announcement of the COVID-19 lockdown (COVID) in Nigeria in four hospitals were used as the sample for this study. All eyes were treatment naïve. We determined the total number of all anti-VEGF injections, the number given for each indication, and the number of each type of the three anti-VEGFs given. A comparison of the presenting vision in IVI eyes between the two eras and the visual outcome of the IVI treatment was made. Data were analyzed using the SPSS version 22 to determine statistical significance.

Results:

Male/female ratio, pre-COVID 63.4%/36.6% and COVID 58.6%/41.4% (P= 0.123). Age, pre-COVID 61.3 (SD 12.9) 9–95 years and COVID 57.5 (SD 16.4) 0.15–95 years. There was a 15.3% (81 eyes) reduction in the number of eyes between pre-COVID and COVID eras (528 and 447 eyes, respectively). Likewise, the number of IVIs reduced by 26% (221 IVIs) from 850 pre-COVID to 629 COVID,P= 0.005. A comparison of the proportion of eyes in the four clinic locations between the two eras was not statistically significant (P= 0.148). The commonest indication was proliferative diabetic retinopathy in both eras, 208 versus 178 eyes (323 versus 226 IVIs). Bevacizumab, Ranibizumab, and Aflibercept were given in the following proportions 60.2%, 22.3%, and 17.4% (pre-COVID) versus 60.2%, 31.5%, and 8.3% (COVID),P= 0.000. Presenting visual acuity was >6/60 in 67.4% of eyes (pre-COVID) versus 59.4% of eyes (COVID),P= 0.039. Vision improved in 51.3% of eyes (pre-COVID) versus 47.7% (COVID); there was no significant difference in visual outcome comparing both eras,P= 0.972.

Conclusion:

COVID-19 significantly reduced the number of eyes and IVIs. Eyes had worse presenting visual acuity during the COVID era; however, treatment outcome was comparable between COVID and pre-COVID eras.