bluuebunny/crossref_metadata_2025 huggingface dataset:
The Effect of TNF and VEGF on the Properties of Ea.hy926 Endothelial Cells in a Model of Multi-Cellular Spheroids
Authors: Gapizov S. Sh. , Petrovskaya L. E. , Shingarova L. N. , Svirschevskaya E. V. , Dolgikh D. A. , Kirpichnikov M. P.
Published: November 2018

Endothelial cells play a major role in the development of inflammation and neoangiogenesis in cancer and chronic inflammatory diseases. In 3D cultures, cells are under conditions that closely resemble those existing in healthy and disease-stricken human organs and tissues. Therefore, the development of a 3D model based on the Ea.hy926 endothelial cell line is an urgent need in molecular and cellular biology. Cell cultivation on an anti-adhesive substrate under static conditions was shown to lead to the formation of spheroids (3D cultures). Expression of ICAM-1 and VEGFR-2 and production of cytokines were screened in 2D and 3D cultures in the presence of TNF and VEGF. According to flow cytometry and confocal microscopy data, TNF significantly increased the expression of the cell adhesion molecule ICAM-1 in both 2D and 3D cultures but did not affect the expression level of VEGFR-2. Increased production of pro-inflammatory (IL-8, IL-6, IP-10) and anti-inflammatory (IL-10, TGF- 1-3) factors was observed in spontaneous 3D cultures but not in 2D cultures, which was confirmed by flow cytometry and qPCR. TNF-induced secretion of IL-10, GM-CSF, and IL-6 was 11-, 4.7-, and 1.6-fold higher, respectively, in 3D cultures compared to 2D cultures. Thus, the use of a Ea.hy926 3D cell culture is a promising approach in studying the effects of anti- and pro-inflammatory agents on endothelial cells.
APLIKASI PENJUALAN DAN PEMBELIAN OBAT PADA APOTEK KINDA FARMA PRABUMULIH
Authors: Fajriyah Fajriyah , Wijaya Khana , Firdasari Ria
Published: November 2018

Perkembangan teknologi saat ini berkembang sangat cepat, teknologi memiliki peran yang sangat penting bagi kebutuhan aktivitas manusia khususnya dalam penggunaan teknologi computer. Komputer sebagai alat pengolahan data yang memiliki kemampuan lebih baik diantaranya dalam hal kecepatan, keakuratan dan efisiensi. Apotek Kinda Farma adalah salah satu apotek yang saat ini membutuhkan pengolahan data yang lebih terkomputerisasi, namun dari hasil observasi Apotek Kinda Farma ini masih melakukan pengolahan data dengan cara pencatatan dalam sebuah buku seperti dalam hal transaksi penjualan dan pembelian obat serta pembuatan laporan. Oleh sebab itu dibutuhkan aplikasi yang dapat memudahkan pencatatan transaksi penjualan dan pembelian obat sehingga informasi yang dihasilkan tepat dan akurat. Kata kunci—Apotek Kinda Farma , aplikasi, penjualan, pembelian, obat
ANALISIS PERANCANGAN APLIKASI MOBILE MINI-UKM: STUDI KASUS UKM DI TASIKMALAYA
Authors: Yohandy Daniel Hadrian
Published: November 2018

ABSTRACT Kemajuan teknologi sudah merambah ke semua tipe dan proses bisnis hingga menjadi suatu persaingan antar perusahaan industri maupun non-industri. Pemanfaatan nilai teknologi pada proses bisnis dapat meningkatkan efisiensi dan efektivitas dari berbagai aspek yang berujung pada peningkatan transaksi dan pengurangan sumber daya untuk menghasilkan keuntungan yang maksimal bagi suatu perusahaan. Enterprise Resource Planning (ERP) sebagai salah satu bentuk pemanfaatan teknologi sudah banyak dipakai di Indonesia namun hanya mencakup perusahaan besar dengan sumber daya yang mumpuni. Tidak seperti di lingkup internasional dimana beberapa Unit Kecil Menengah (UKM) sudah dapat menerapkan ERP, di Indonesia mayoritas UKM masih sedikit atau bahkan belum menerapkan nilai teknologi secara konsisten ke proses bisnis mereka. Penelitian ini menggunakan kerangka ERP Framework untuk menganalisis sistem ERP berbasis mobile yang sesuai untuk UKM di Tasikmalaya menggunakan data yang diperoleh dari in-depth interview dengan beberapa pemilik UKM. Hasil yang didapatkan adalah poin-poin penting sebagai dasar untuk perancangan mini-UKM mobile yang sesuai untuk UKM tradisional terutama di Tasikmalaya. Keywords: Unit Kecil Menengah, Enterprise Resource Planning, ERP Framework, Mobile ABSTRACTTechnological advances have penetrated into all types and business processes to become a competition between industrial companies and non-industrial. Utilization of technology value in business process can increase efficiency and effectivity from various aspect which lead to increase transaction and reduction of resources to yield maximum profit for a company. Enterprise Resource Planning (ERP) as one form of technology utilization has been widely used in Indonesia but only includes large companies with qualified resources. Unlike in the international sphere where some Small Medium Enterprise (UKM) have been able to implement ERP, in Indonesia the majority of UKMs are still few or even have not applied the value of technology consistently to their business processes. This study uses the ERP Framework framework to analyze a mobile based ERP system appropriate for UKMs in Tasikmalaya using data obtained from in-depth interviews with some UKM owners. The results obtained are important points as the basis for the design of mobile mini-UKM appropriate for traditional UKMs, especially in Tasikmalaya.Keywords: Small Medium Enterprise, Enterprise Resource Planning, ERP Framework, Mobile
PENERAPAN FINITE STATE MACHINE UNTUK PENGENDALIAN ANIMASI PADA VIDEO GAME RPG NUSANTARA LEGACY
Authors: Mustofa Mustofa , Sidiq Sidiq , Rahmawati Eva
Published: November 2018

Perkembangan dunia yang dinamis mendorong percepatan perkembangan teknologi dan informasi. Dengan dorongan tersebut komputer yang dulunya dibuat hanya untuk membantu pekerjaan manusia sekarang berkembang menjadi sarana hiburan, permainan, komunikasi dan lain sebagainya. Dalam sektor hiburan salah satu industri yang sedang menjadi pusat perhatian adalah industri video game. Begitu banyaknya produk video game asing yang masuk ke dalam negeri ini memberikan tantangan kepada bangsa ini. Tentunya video game asing yang masuk ke negara ini membawa banyak unsur kebudayaan negara lain. Ini semakin membuat kebudayaan nusantara semakin tergeserkan dengan serangan kebudayaan asing melalui berbagai media. Maka dari itu peneliti mencoba untuk menerapkan Finite State Machine dalam merancang sebuah video game RPG (Role-Playing game) yang memperkenalkan kebudayaan. Dalam perancangan video game ini peneliti menggunakan metode GDLC(Game Development Life Cycle) agar penelitian ini berjalan secara sistematis. Dalam suatu perancangan video game tedapat banyak elemen, pada penelitian ini penulis lebih fokus pada pengendalian animasi karakter yang dimainkan pada video game ini. Dari perancangan yang dilakukan, disimpulkan bahwa Finite State Machine dapat digunakan untuk pengendalian animasi yang baik pada video game RPG. Diharapkan video game ini dapat menjadi salah satu media untuk mengenalkan kebudayaan nusantara
SISTEM SMART PARKING MENGGUNAKAN ULTRASONIK SENSOR
Authors: Kurniawan Rudi , Zulius Antoni
Published: November 2018

AbstrakKebutuhan akan halaman parkir Tentunya menjadi fasilitas utama di suatu perkantoran. Ketika sedang banyak pengunjung yang datang, halaman parkir menjadi penuh. Terkadang juga ada halaman parkir yang tampak penuh di depan, tetapi kosong di belakang. Hal ini menjadi suatu permasalahan, karena ketidaktahuan pengunjung, maka banyak pengunjung Kantor Kecamatan yang memarkir kendaraannya di luar halaman parkir Kecamatan. Kejadian seperti ini dapat kita atasi dengan memberikan suatu tanda yang dapat menjadi indikator apakah ada lahan parkir yang kosong atau tidak. Sistem seperti ini dapat dirancang dengan menggunakan suatu kontrol otomatis dengan meletakkan sensor di tempat parkir. Sensor yang digunakan dapat berupa Ultrasonik Sensor. Sensor ini sangat sensitif terhadap pergerakan. Perubahan gerak yang dirasakan oleh sensor dapat mengirimkan sinyal ke modul kontrol arduino untuk segera diproses dan dikirimkan ke lampu indikator LED. Kata kunci— Arduino, Ultrasonic Sensor, Smart Parking
ANALISIS DAN PERANCANGAN SISTEM INFORMASI SMP NEGERI 38 OKU
Authors: Akmibaturaja Wisnu Murti
Published: November 2018

Perkembangan dalam dunia teknologi khususnya internet banyak sekali diminati masyarakat. Salah satunya World Wide Web ( WWW ) atau yang dikenal dengan website merupakan salah satu fasilitas di Internet yang meluas dan merupakan salah satu media informasi dan sekaligus sebagai sarana promosi. semakin pesatnya perkembangan dunia IT semakin banyak perusahaan/instansi pendidikan yang mulai melirik internet sebagai salah satu media informasi yang digunakan untuk menyampaikan informasi oleh berbagai pihak termasuk instansi pendidikan dalam memberikan informasi tentang mutu pendidikan di sekolah. Dalam perkembangan sebuah sistem informasi jarak jauh yang memberikan hak akses khusus bagi anggotanya ini  mulai digunakan sebagai sarana untuk menghubungkan antar pengguna internet dalam sebuah sistem pengolahan database. website SMP Negeri 38 OKU dibuat menggunakan PHP dan MYSQL serta aplikasi-aplikasi pendukung lainnya seperti adobe photoshop.  website SMP Negeri 38 OKU berisi tentang beberapa halaman yang saling berhubungan yaitu halaman sejarah, struktur organisasi, fasilitas, data guru dan prestasi, sehingga masyarakat lebih mudah untuk mengetahui Informasi SMP Negeri 38 OKU. Kata Kunci— Internet, Website, Informasi
Partisipasi Anggaran dan Implementasi Sistem Informasi Akuntansi Terhadap Kinerja Manajerial
Authors: Yudista Ofan Maulana , SE Amilin , SE Surtikanti
Published: November 2018

 

This research analyzes some factors that influence managerial performance. This research focus on  participation of estimates on their had and implementation of accounting information system. Sample in this research using purpostive sampling that appropriate with the  criteria till using the sample as many as 86 samples. The result of the research shows that budget  participation has a significance possitive effect (direct) to magerial performance directly. Accounting Information System has a significance possitive effect to managerial performance directly. Budget participation has a significance possitive effect to managerial performance trough accounting information system indirectly. Accounting information system has a significance possitive effect to managerial performance trough budget participation as an intervening variable indirectly

 
Motivasi, Komunikasi, dan Kepuasan Kerja Terhadap Kinerja Tenaga Kependidikan Pada Fakultas Insititut Pertanian Bogor
Authors: Nooryani Sri , Tanjung Hendri , MA Ibdalsyah
Published: November 2018

The path analysis shows that motivation has significantly direct and indirect effects to communication. Motivation does not have significant effects to performance but have indirect effects through job satisfaction. This is because motivation has significant direct effects to job satisfaction. Communication has direct and indirect effects to performance. The indirect effect is through job satisfaction. Job satisfaction has significant direct effects to performance.

The T-test results show that the effects of independent variables (motivation and communication) have significant positive effects to job satisfaction with p-value of 0.00. This value is less than alpha value (5%). Coefficient determination (R2) is of 0.741. This means that motivation and communication can explain the diversity of job satisfaction as high as 74.1% and the rest, which is of 25.9%, explains by other factors that are not used in this research. Independent variables (motivation, communication and job satisfaction) have significant positive effects to performance with p-value of 0.00. The coefficient determination (R2) is of 0.574. This means that motivation, communication, and job satisfaction can explain performance as high as 57.4% and the rest, which is of 42.6%, explains by other factors.

 
Compensation, Organizational Culture, Education/Training of Work Motivation And Impact on The Performance Employees (Case Study : Hotel Sofyan Betawi, Jakarta)
Authors: Widiargo Ruhadi , Walujadi Dedi , Pasaribu Popy Novita
Published: November 2018

The purpose of this study was to analyze the effect of compensation, organizational culture, education/training on work motivation both individually and collectively together and to analyze the effect of compensation, motivation, education/training on performance either individually or jointly, as well as to analyze the effect of compensation, organizational culture, education/training on performance through motivation to work at Hotel Sofyan Betawi, Cut Meutia, Jakarta.
The population consisted of all employees, as many as 80 people. Using census sampling techniques to the overall population of 80 people or respondents, data collection was conducted using questionnaires, while data analysis using path analysis or path analysis were processed using SPSS 16 software. The results showed that: (1) Compensation and organizational culture had no significant effect on work motivation, while education/training has significant effect on work motivation, (2) Compensation, organizational culture, education/training jointly significant effect on motivation, (3) Compensation does not significantly affect the performance of the employee, while the motivation and education/training significantly affect performance, (4) compensation, motivation, education/training jointly significant effect on performance, (5) Compensation, organizational culture, education/training has positive influence on performance through motivation.
Kepercayaan dan Keamanan Konsumen terhadap Minat Beli di situs Online (Studi Kasus pengunjung situs Lazada di Jakarta Timur)
Authors: Anwar Resa Nurlela , Afifah Aulia
Published: November 2018

The internet is growing rapidly with an increasing number of regular users. Many people cannot escape the internet in their daily lives and this affects their consumption patterns. The internet has an important role in supporting the development of e-commerce in conducting online transactions. Many online shopping stores have sprung up making people more often make purchasing decisions on a product, and online shopping alone is considered to be much easier and more effective. The purpose of this study was to determine and analyze the influence of consumer trust and security on buying interest on the Lazada site (Survey of visitors to the Lazada site in East Jakarta). The population in this study is Lazada Site Visitors who reside in East Jakarta during January - June 2018 with a total sample of 100 respondents selected using purposive sampling technique. Primary data collection using questionnaires and secondary data collection using literature study. Testing the hypothesis in this study using multiple linear regression analysis with a significance value of a = 10% (0.10). The results showed that trust and security partially and simultaneously have a significant effect on corporate image. Partially, confidence influences asking for a purchase of 9.3% and security has a significant effect on buying interest of 6.3%. The R Square value obtained through testing the determinant coefficient (R2) is what means that advertising affects the company's image by 15.9% and the rest is influenced by other factors not examined in this study.
Xây dựng độ đo thuần nhất và nâng cao độ tương phản của ảnh màu theo tiếp cận trực tiếp dựa trên đại số gia tử
Authors: Quyền Nguyễn Văn , Huy Ngô Hoàng , Hồ Nguyễn Cát , Sơn Trần Thái
Published: November 2018

Các kỹ thuật nâng cao tương phản ảnh đã thu hút nhiều sự quan tâm của cộng đồng xử lý ảnh vì chúng giúp cải thiện khả năng phân tích hình ảnh, thị lực máy tính, v.v. Trong các phương pháp nâng cao độ tương phản ảnh, các phương pháp trực tiếp thiết lập một độ đo tương phản và nâng cao chất lượng hình ảnh bằng cách cải thiện độ đo tương phản. Tuy nhiên, hiện có rất ít các nghiên cứu theo phương pháp trực tiếp, chỉ có các nghiên cứu của Cheng và Xu là đề xuất một phương pháp thay đổi độ tương phản tại mỗi điểm ảnh sử dụng độ đo tương phản được tính dựa trên độ thuần nhất của điểm ảnh. Trong bài báo này, chúng tôi đề xuất một phương pháp xây dựng độ thuần nhất mới dựa trên đại số gia tử. Các kết quả thực nghiệm cho thấy phương pháp nâng cao độ tương phản trực tiếp được thực hiện tốt với nhiều loại ảnh màu khác nhau khi áp dụng phép đo độ thuần nhất đề xuất. DOI: 10.32913/rd-ict.vol2.no38.381
Tổng hợp tiếng Việt có cảm xúc
Authors: Thành Lê Xuân , Loan Trịnh Văn , Quang Nguyễn Hồng , Thủy Đào Thị Lệ , Lưỡng Đinh Đồng
Published: November 2018

Tiếng Việt là ngôn ngữ đơn âm tiết và có thanh điệu. Để tổng hợp tiếng Việt chất lượng tốt, việc đảm bảo chất lượng của thanh điệu tổng hợp sao cho càng gần với thanh điệu tự nhiên là rất quan trọng. Bài báo này đề xuất một phương pháp tổng hợp tiếng Việt dựa trên ghép nối âm vị kép, trong đó các biến thiên F0 của các âm được tổng hợp giống như biến thiên F0 của tiếng nói tự nhiên. Hơn nữa, để tích hợp cảm xúc vào tiếng Việt tổng hợp, bài báo trình bày một phương pháp tổng hợp dựa trên mô hình Fujisaki. Ba cảm xúc khác nhau được thử nghiệm là buồn, tức và vui. Các kết quả đánh giá khách quan và chủ quan chất lượng tiếng Việt tổng hợp cũng được trình bày trong nghiên cứu này. DOI: 10.32913/rd-ict.vol2.no38.615
Whither Hamlet's “Words, Words, Words”? Notes on Dialogue and Designs in Hamlet
Authors: Clayton Tom
Published: November 2018

Four Hamlets and Hamlets have evolved from recent text-editorial practice, corresponding with, respectively, Q1 1603, Q2 1604–05, F 1623, and the composite received text combining Q2 and F. Q2 is the fullest and most authoritative text, F is a slightly shorter, cut revision containing passages omitted in Q2. At present, Q1—half the length of Q2—is either young Shakespeare's first version or, more likely, a later derivative of F1's ancestor (c. 1601–03). Although the most recent editors (of Arden 3 and the New Oxford Shakespeare) favor individual editions of Q1, Q2, and F, there remains much to be said for the received composite text that intercuts longer passages omitted in Q2 and F as a reader's text of the whole literary Hamlet. This Hamlet benefits from full dialogue by and about the Prince, including his important speeches cut in F and in most productions, 1.4.17–38 (notably “So oft it chances”), and his last soliloquy, 4.4.32–66 (“How all occasions do inform against me”). The whole Hamlet is a salutary corrective to the post-Romantic Hamlet-as-Coleridge and Olivier's voice-overed “man who could not make up his mind.” Not mad, he feigns well in prose that serves as easily in genial conversation with those of lower social station—guards, players, gravediggers—and like much else shows him something of a mensh. Hamlet was every inch a king-in-waiting (not much longer: “This is I, Hamlet the Dane”), and he dies, politically responsible, casting his vote for Fortinbras. In the perspective of our own time, “His greatest operational weapon is his humanity.”
Ellipsis of Grammatology: Derrida's Beautiful Passages
Authors: Düttmann Alexander García
Published: November 2018

Beautiful passages are passages of ‘pure presence’ inasmuch as they cannot be separated from an absence, from an absence that cannot be revoked by restoring a ‘pure presence’. Beautiful passages are passages that move and inspire because they do not withhold anything, though their gift and their surrender lies in an ellipsis that is essential to ‘pure presence’ and that cannot be sidestepped, as if a remainder, a reserve, or a surplus inhered in them. It is impossible to get a grip on beautiful passages. They are riddles that have been solved but persist in the midst of their solution and do not forfeit any of their enigmaticalness. Their beauty resides in an experience of intensity, in an experience based on an elision, on a tightening and an averting. Such averting is an immediate turning towards the one who feels the intensity, touching and stimulating him as a consequence. This paper explores the question: Are there beautiful passages in Of Grammatology?
Putting Truth to the Test of Forgiveness: Reading Jacques Derrida's Seminar, ‘Le parjure et le pardon’ (‘Perjury and Forgiveness’), translated by Cosmin Toma
Authors: Michaud Ginette
Published: November 2018

This paper has been translated from the French by Cosmin Toma. It focuses on Jacques Derrida's very last lecture, given in Rio de Janeiro, on the 16thof August 2004, which Derrida drew from his ‘Le parjure et le pardon’ (‘Perjury and Forgiveness’) seminar held at the École des hautes études en sciences sociales (EHESS), in Paris, from 1997 to 1999. In reference to this final lecture in which Derrida deals with ‘forgiveness,’ ‘truth’, ‘reconciliation’, ‘testimony’ and ‘genre’, the paper also takes up the question of justice as well as of what he calls the ‘worst violence’ via testimonial writings by Sarah Kofman and Antjie Krog so as to rethink forgiveness.
The Regulatory Framework for Safety Management Systems in Airworthiness Organisations
Authors: Batuwangala Eranga , Silva Jose , Wild Graham
Published: November 2018

In recent years, a growing emphasis on safety has driven various industries, both in manufacturing and service, to implement a Safety Management System (SMS) in their organisations. SMSs have also been widely implemented in aviation due to both regulatory requirements and voluntary implementation with the aim of decreasing incidents and accidents whilst reducing inefficiencies and costs stemming from the repercussions of safety failures. The aviation industry involves various players for the provision of services ranging from airline operations, maintenance, aerodrome operations, air traffic services, aircraft and component design, manufacturing, and training. Not all organisations in the aviation industry have implemented SMSs. Furthermore, SMS is currently not regulated for all aviation organisations. Whilst technology has played a key role in driving down the number of accidents and incidents in aviation, the growth in air traffic demands having programs in place to further drive down accident rates. In this context, this article provides an investigation to the regulatory framework for the implementation of SMSs in aviation, including the requirements stipulated by the International Civil Aviation Organisation (ICAO) and the status of SMS regulation of key National Aviation Authorities (NAA) and Military Aviation Authorities (MAA), with a focus on organisations involved in airworthiness including initial and continuing airworthiness. This article also investigates the challenges of implementing SMSs in organisations involved in Airworthiness, as well as the benefits that could be gained by service providers as well as NAA’s or MAA’s through SMSs.
A Redneck Head on a Nazi Body. Subversive Ludo-Narrative Strategies in Wolfenstein II: The New Colossus
Authors: Backe Hans-Joachim
Published: November 2018

This article argues that Wolfenstein: The New Colossus, a AAA First-Person Shooter, is not only politically themed, but presents in itself a critical engagement with the politics of its genre and its player base. Developed at the height of #Gamergate, the game is interpreted as a response to reactionary discourses about gender and ability in both mainstream games and the hardcore gamer community. The New Colossus replaces affirmation of masculine empowerment with intersectional ambiguities, foregrounding discourses of feminism and disability. To provoke its players without completely alienating them, the game employs strategies of carnivalesque aesthetics—especially ambivalence and grotesque excess. Analyzing the game in the light of Bakhtinian theory shows how The New Colossus reappropriates genre conventions pertaining to able-bodiedness and masculinity and how it “resolves” these issue by grafting the player character’s head on a vat-grown Nazi supersoldier-body. The breaches of genre conventions on the narrative level are supported by intentionally awkward and punishing mechanics, resulting in a ludo-narrative aesthetic of defamiliarization commensurate to a grotesque story about subversion and revolt. Echoing the ritualistic cycle of death and rebirth at the heart of carnivalesque aesthetics, The New Colossus is nothing short of an ideological re-invention of the genre.
Development of Intelligent Drone Battery Charging System Based on Wireless Power Transmission Using Hill Climbing Algorithm
Authors: Rohan Ali , Rabah Mohammed , Talha Muhammad , Kim Sung-Ho
Published: November 2018

In this work, an advanced drone battery charging system is developed. The system is composed of a drone charging station with multiple power transmitters and a receiver to charge the battery of a drone. A resonance inductive coupling-based wireless power transmission technique is used. With limits of wireless power transmission in inductive coupling, it is necessary that the coupling between a transmitter and receiver be strong for efficient power transmission; however, for a drone, it is normally hard to land it properly on a charging station or a charging device to get maximum coupling for efficient wireless power transmission. Normally, some physical sensors such as ultrasonic sensors and infrared sensors are used to align the transmitter and receiver for proper coupling and wireless power transmission; however, in this system, a novel method based on the hill climbing algorithm is proposed to control the coupling between the transmitter and a receiver without using any physical sensor. The feasibility of the proposed algorithm was checked using MATLAB. A practical test bench was developed for the system and several experiments were conducted under different scenarios. The system is fully automatic and gives 98.8% accuracy (achieved under different test scenarios) for mitigating the poor landing effect. Also, the efficiency η of 85% is achieved for wireless power transmission. The test results show that the proposed drone battery charging system is efficient enough to mitigate the coupling effect caused by the poor landing of the drone, with the possibility to land freely on the charging station without the worry of power transmission loss.
Ultrasonic Power to Enhance Limestone Dissolution in the Wet Flue Gas Desulfurization Process. Modeling and Results from Stepwise Titration Experiments
Authors: De Blasio Cataldo , Carletti Claudio , Salonen Jarno , Björklund-Sänkiaho Margareta
Published: November 2018

The goal of this work is to assess the application of ultrasonic power to the reactive dissolution of limestone particles in an acidic environment; this would represent a novel method for improving wet Flue Gas Desulfurization industrial systems. In this study a stepwise titration method is utilized; experiments were done by using different particle size distributions with and without the application of ultrasound. The use of ultrasonic power sensibly affected the reaction rate of limestone and its dissolution; a major difference could be observed when samples from the Wolica region in Poland were studied. In this case, the overall dissolution rate was found to increase by more than 70%. The reactive dissolution of limestone does not follow the same mathematical model when sonication is in effect; in this case, an extra Ultrasonic Enhancement Constant was introduced. It was demonstrated that the dissolution is proportional to an Effective Reaction Surface and, therefore, surface interactions should also be taken into consideration. For this purpose, a study is presented here on the Z-potential and electrophoretic mobility of limestone samples measured in aqueous dispersions by means of Laser Doppler Micro-Electrophoresis.
Application of Rough Set Theory to Water Quality Analysis: A Case Study
Authors: Zavareh Maryam , Maggioni Viviana
Published: November 2018

This work proposes an approach to analyze water quality data that is based on rough set theory. Six major water quality indicators (temperature, pH, dissolved oxygen, turbidity, specific conductivity, and nitrate concentration) were collected at the outlet of the watershed that contains the George Mason University campus in Fairfax, VA during three years (October 2015–December 2017). Rough set theory is applied to monthly averages of the collected data to estimate one indicator (decision attribute) based on the remainder indicators and to determine what indicators (conditional attributes) are essential (core) to predict the missing indicator. The redundant attributes are identified, the importance degree of each attribute is quantified, and the certainty and coverage of any detected rule(s) is evaluated. Possible decision making rules are also assessed and the certainty coverage factor is calculated. Results show that the core water quality indicators for the Mason watershed during the study period are turbidity and specific conductivity. Particularly, if pH is chosen as a decision attribute, the importance degree of turbidity is higher than the one of conductivity. If the decision attribute is turbidity, the only indispensable attribute is specific conductivity and if specific conductivity is the decision attribute, the indispensable attribute beside turbidity is temperature.
A Versatile Setup for Measuring Multiple Behavior Endpoints in Zebrafish
Authors: Audira Gilbert , Sampurna Bonifasius Putera , Juniardi Stevhen , Liang Sung-Tzu , Lai Yu-Heng , Hsiao Chung-Der
Published: November 2018

The measurement of multiple behavior endpoints in zebrafish can provide informative clues within neurobehavioral field. However, multiple behavior evaluations usually require complicated and costly instrumental settings. Here, we reported a versatile setting that applied ten acrylic tanks arranging into five vertical layers and two horizontal columns to perform multiple behavior assays simultaneously, such as the novel tank diving test, mirror-biting test, social interaction, shoaling, and predator escape assay. In total, ten behavioral performance were collected in a single video, and the XY coordination of fish locomotion can be tracked by using open source software of idTracker and ImageJ. We validated our setting by examining zebrafish behavioral changes after exposure to low dose ethanol (EtOH) for 96 h. Fish were observed staying longer time at bottom of the tank, less mirror biting interest, higher freezing time, less fear in predator test, and tight shoaling behaviors which indicated the anxiogenic effect was induced by low dosage exposure of EtOH in zebrafish. In conclusion, the setting in this study provided a simple, versatile and cost-effective way to assess multiple behavioral endpoints in zebrafish with high reliability and reproducibility for the first time.
Hypertension Status and Associations with Self-Rated Health and General Practitioner Health Seeking in a Rural Australian Cohort
Authors: Gavino Alex I. , Isaac Vivian , McLachlan Craig S.
Published: November 2018

Hypertension is the most frequently managed condition by Australian general practitioners (GP). Knowledge of hypertension and blood pressure (BP) values may motivate individuals to seek GP management. Our study aims to determine the associations of knowledge of BP values, BP perception, GP health seeking, and self-rated health (SRH) in a rural population. Two-hundred and seventy-eight (278) residents responded to the health survey on socio-demographic profile, medical history, BP knowledge and perception, SRH, and GP visit frequency. Associations were evaluated using Chi-squared test and multivariate logistic regression. Cohort mean age was 63.6 (12.4) years with 63.3% females. Hypertension (37.8%) was the most common condition. GP visits were made at least once every month (19.1%), every 2–6 months (35.6%), >6 months (11.5%), or only when needed (29.5%). Univariate analyses showed age, education, alcohol consumption, comorbidities, hypertension status, and SRH were significantly associated with visit frequency. After adjustments, hypertension status (OR = 3.6, 95% CI [1.7, 7.9]) and poor SRH (OR = 3.1, 95% CI [1.4, 7.0]) were significantly associated with frequent monthly visits. Our cohort demonstrated that having hypertension and poor self-rated health were associated with frequent monthly GP visits. The perception of high blood pressure does not drive seeking additional GP input.
On the High Formability of AZ31-0.5Ca Magnesium Alloy
Authors: Masood Chaudry Umer , Hoo Kim Tae , Duck Park Sang , Sik Kim Ye , Hamad Kotiba , Kim Jung-Gu
Published: November 2018

In this work, we investigated the effect of Ca on the formability of the AZ31 Mg alloy. For this purpose, the microstructure, texture, mechanical properties and formability of AZ31 Mg alloy samples containing 0.5 wt. % Ca (AZ31-0.5Ca) were studied. For comparison, the performance of Ca-Free AZ31 alloy samples with similar grain size was also investigated. In addition, formability of this alloy was reached at a high punch speed. The results of this work showed that the addition of 0.5 wt. % Ca can enhance the formability of the AZ31 alloy, which was three times greater than that of the Ca-Free AZ31 alloy. The improved formability was attributed to the formation of (Mg,Al)2Ca particles (~1 μm), which, in turn, contribute to reducing the intensity of the strong basal texture during the primary processing of the alloy. The in-grain misorientation axis analysis determined by electron back-scattered diffraction and critical resolved shear stress calculations carried out by the viscoplastic self-consistent model showed that the non-basal slip systems could be activated in the AZ31-0.5Ca alloy.
Electron-Transfer Properties of Phenyleneethynylene Linkers Bound to Gold via a Self-Assembled Monolayer of Molecular Tripod
Authors: Kitagawa Toshikazu , Kawano Takashi , Hase Takahiro , Hayakawa Ikuma , Hirai Katsuyuki , Okazaki Takao
Published: November 2018

The three-point adsorption of tripod-shaped molecules enables the formation of robust self-assembled monolayers (SAMs) on solid surfaces, where the component molecules are fixed in a strictly upright orientation. In the present study, SAMs of a rigid molecular tripod consisting of an adamantane core and three CH2SH groups were employed to arrange ferrocene on a gold surface through oligo(p-phenyleneethynylene) linkers. Cyclic voltammetry of the monolayers demonstrated high surface coverage of ferrocene, yet the molecular interaction among adjacent ferrocene units was negligible. This was because of the extended intermolecular distance caused by the bulky tripod framework. The rates of electron transfer from the ferrocene to the gold surface through different linker lengths were determined by electrochemical measurements, from which the decay factor for oligo(p-phenyleneethynylene) wire was evaluated.
Locating Religion and Secularity in East Asia Through Global Processes: Early Modern Jesuit Religious Encounters
Authors: Casanova Jose
Published: November 2018

The central premise of this paper is that in order to understand the social construction of religion and secularity in East Asia today we need to take a long durée historical approach, which takes into account the colonial encounters between the Christian West and East Asia during three different and distinct phases of globalization. While most of the recent scholarly work on the globalization of the categories of religion and secularity focuses on the second Western hegemonic phase of globalization, this essay focuses on the early modern phase of globalization before Western hegemony.
The Fundamental Equity Premium and Ambiguity Aversion in an International Context
Authors: Ngo Minh , Rieger Marc , Yuan Shuonan
Published: November 2018

Stocks are riskier than bonds. This causes a risk premium for stocks. That the size of this premium, however, seems to be larger than risk aversion alone can explain the so-called “equity premium puzzle”. One possible explanation is the inclusion of a degree of ambiguity in stock returns to account for an additional ambiguity premium, whose size depends on the degree of ambiguity aversion among investors. It is, however, difficult to test this empirically. In this paper, we compute the first firm-level estimation of equity premium based on the internal rate of return (IRR) approach for a total of N = 28,256 companies in 54 countries worldwide. Using a survey of international data on ambiguity aversion, we find a strong and robust relation between equity premia and ambiguity aversion.
Wearable Hardware Design for the Internet of Medical Things (IoMT)
Authors: Qureshi Fayez , Krishnan Sridhar
Published: November 2018

As the life expectancy of individuals increases with recent advancements in medicine and quality of living, it is important to monitor the health of patients and healthy individuals on a daily basis. This is not possible with the current health care system in North America, and thus there is a need for wireless devices that can be used from home. These devices are called biomedical wearables, and they have become popular in the last decade. There are several reasons for that, but the main ones are: expensive health care, longer wait times, and an increase in public awareness about improving quality of life. With this, it is vital for anyone working on wearables to have an overall understanding of how they function, how they were designed, their significance, and what factors were considered when the hardware was designed. Therefore, this study attempts to investigate the hardware components that are required to design wearable devices that are used in the emerging context of the Internet of Medical Things (IoMT). This means that they can be used, to an extent, for disease monitoring through biosignal capture. In particular, this review study covers the basic components that are required for the front-end of any biomedical wearable, and the limitations that these wearable devices have. Furthermore, there is a discussion of the opportunities that they create, and the direction that the wearable industry is heading in.
Toxin Profiles of Okadaic Acid Analogues and Other Lipophilic Toxins in Dinophysis from Japanese Coastal Waters
Authors: Uchida Hajime , Watanabe Ryuichi , Matsushima Ryoji , Oikawa Hiroshi , Nagai Satoshi , Kamiyama Takashi , Baba Katsuhisa , Miyazono Akira , Kosaka Yuki , Kaga Shinnosuke , Matsuyama Yukihiko , Suzuki Toshiyuki
Published: November 2018

The identification and quantification of okadaic acid (OA)/dinophysistoxin (DTX) analogues and pectenotoxins (PTXs) in Dinophysis samples collected from coastal locations around Japan were evaluated by liquid chromatography mass spectrometry. The species identified and analyzed included Dinophysis fortii, D. acuminata, D. mitra (Phalacroma mitra), D. norvegica, D. infundibulus, D. tripos, D. caudata, D. rotundata (Phalacroma rotundatum), and D. rudgei. The dominant toxin found in D. acuminata was PTX2 although some samples contained DTX1 as a minor toxin. D. acuminata specimens isolated from the southwestern regions (Takada and Hiroshima) showed characteristic toxin profiles, with only OA detected in samples collected from Takada. In contrast, both OA and DTX1, in addition to a larger proportion of PTX2, were detected in D. acuminata from Hiroshima. D. fortii showed a toxin profile dominated by PTX2 although this species had higher levels of DTX1 than D. acuminata. OA was detected as a minor toxin in some D. fortii samples collected from Yakumo, Noheji, and Hakata. PTX2 was also the dominant toxin found among other Dinophysis species analyzed, such as D. norvegica, D. tripos, and D. caudata, although some pooled picked cells of these species contained trace levels of OA or DTX1. The results obtained in this study re-confirm that cellular toxin content and profiles are different even among strains of the same species.
Solar Neutrinos Spectroscopy with Borexino Phase-II
Authors: Miramonti Lino , Agostini Matteo , Altenmueller Konrad , Appel Simon , Atroshchenko Victor , Bagdasarian Zara , Basilico Davide , Bellini Gianpaolo , Benziger Jay , Bick Daniel , Bolognino Irene , Bonfini Giuseppe , Bravo David , Caccianiga Barbara , Calaprice Frank , Caminata Alessio , Caprioli Silvia , Carlini Marco , Cavalcante Paolo , Cavanna Francesca , Chepurnov Alexander , Choi Koun , Collica Laura , Davini Stefano , Derbin Alexander , Ding XueFeng , Di Ludovico Antonio , Di Noto Lea , Drachnev Ilia , Fomenko Kirill , Formozov Andrey , Franco Davide , Gabriele Federico , Galbiati Cristiano , Gschwender Michael , Ghiano Chiara , Giammarchi Marco , Goretti Augusto , Gromov Maxim , Guffanti Daniele , Hagner Caren , Houdy Thibaut , Hungerford Ed , Ianni Aldo , Ianni Andrea , Jany Anna , Jeschke Dominik , Kobychev Vladislav , Korablev Denis , Korga Gyorgy , Lachenmaier Tobias , Laubenstein Matthias , Litvinovich Evgeny , Lombardi Francesco , Lombardi Paolo , Ludhova Livia , Lukyanchenko Georgy , Lukyanchenko Liudmila , Machulin Igor , Manuzio Giulio , Marcocci Simone , Maricic Jelena , Martyn Johann , Meroni Emanuela , Meyer Mikko , Misiaszek Marcin , Muratova Valentina , Neumair Birgit , Oberauer Lothar , Opitz Bjoern , Orekhov Vsevolod , Ortica Fausto , Pallavicini Marco , Papp Laszlo , Penek Omer , Pietrofaccia Lidio , Pilipenko Nelly , Pocar Andrea , Porcelli Alessio , Raikov Georgy , Ranucci Gioacchino , Razeto Alessandro , Re Alessandra , Redchuk Mariia , Romani Aldo , Rossi Nicola , Rottenanger Sebastian , Schöenert Stefan , Semenov Dmitrii , Skorokhvatov Mikhail , Smirnov Oleg , Sotnikov Albert , Stokes Lee F. F. , Suvorov Yura , Tartaglia Roberto , Testera Gemma , Thurn Jan , Toropova Maria , Unzhakov Evgenii , Vishneva Alina , Vogelaar Bruce , Von Feilitzsch Franz , Weinz Stefan , Wojcik Marcin , Wurm Michael , Yokley Zachary , Zaimidoroga Oleg , Zavatarelli Sandra , Zuber Kai , Zuzel Grzegorz
Published: November 2018

Solar neutrinos have played a central role in the discovery of the neutrino oscillation mechanism. They still are proving to be a unique tool to help investigate the fusion reactions that power stars and further probe basic neutrino properties. The Borexino neutrino observatory has been operationally acquiring data at Laboratori Nazionali del Gran Sasso in Italy since 2007. Its main goal is the real-time study of low energy neutrinos (solar or originated elsewhere, such as geo-neutrinos). The latest analysis of experimental data, taken during the so-called Borexino Phase-II (2011-present), will be showcased in this talk—yielding new high-precision, simultaneous wide band flux measurements of the four main solar neutrino components belonging to the “pp” fusion chain (pp, pep, 7 Be, 8 B), as well as upper limits on the remaining two solar neutrino fluxes (CNO and hep).
Phénomènes karstiques et pseudo-karstiques dans des quartzites au Burundi
Authors: Peyrot Bernard
Published: November 2018

A côté d'un karst souterrain de type classique creusé dans les séries carbonatées d'Afrique centrale, des grottes et des phénomènes karstiques de surface existent également dans des séries quartzitiques comme c'est le cas au Burundi. L'arénisation de ces roches dans des structures fragilisées se produit dans un contexte très humide à forte activité biologique qui est à l'origine de cavités originales, de reliefs ruiniformes et de lapiés de surface.
Phénomènes pseudo-karstiques dans les roches plutoniques et métamorphiques du Sud du Cameroun
Authors: Vicat Jean Paul , Lips Bernard , Pouclet André , Léger Jean-Marc , Willems Luc
Published: November 2018

De nombreuses formes d'altération pseudo-karstiques de surface et de profondeur s'observent dans les roches plutoniques et métamorphiques du Sud du Cameroun. Les formes superficielles sont pour la plupart actuelles. Les formes profondes sont fossiles et postérieures à la surface fini-crétacée. Les phénomènes observés sont attribués à la dissolution des plagioclases par les eaux pluviales acides.
Les nomades lours du massif calcaire du Kuh-e-Garrin (Zagros central, Iran)
Authors: Dumas Dominique
Published: November 2018

The lours nomads of the Kuh-e-Garrin limestone massif (Central Zagros, Iran). Today many nomadic confederations live in the Zagros range. For a long time, these high mountains have offered these populations both shelter and a large territory which is not as arid as the piedmont plains due to orographic rainfall. Whereas the Baxtyari and Qashqaï are well described in the literature, little is known about the Lours nomads. In this paper, observations and investigations on nomadic families (Summers 1994, 1995, 1996) are presented together with the characteristics of their seasonal migrations. The socio-economic dimension of these populations is also studied to explain the reasons which account for the overgrazing clearly visible in all Zagros mountains. Today, these high mountain karsts are subject to a higher anthropogenic pressure than previously, which entails an irreversible disappearance of vegetation and soils.
La cristallogenèse des spéléothèmes de la grotte Lithophagus (Monts Pâdurea Craiului, Roumanie)
Authors: Ghergari Lucrecia , Onac Bogdan P. , Vremir Matei , Strusievicz Robert
Published: November 2018

La grotte Lithophagus abrite des spéléothèmes calcitiques (stalactites, stalagmites, cristaux, excentriques, fongites) mono- et polycristallins particulièrement intéressants. Leur étude a permis d'identifier les formes cristallographiques qui les composent, d'analyser en détail le phénomène de maclage et de mettre en évidence l'existence de plusieurs générations de cristaux. Une attention spéciale a été accordée aux stalactites et aux excentriques, une analyse des directions préférentielles d'accroissement étant effectuée pour ces derniers. Les données statistiques mettent en évidence plusieurs rapports entre les formes cristallographiques qui apparaissent dans une certaine catégorie de spéléothèmes, la fréquence de ceux-ci et les variations que le topoclimat et la topographie de la cavité impriment aux conditions de développement.
Sur l'origine des karsts du bassin des lulliminden au Niger
Authors: Bouzou Moussa Ibrahim , Schoeneich Philippe
Published: November 2018

Genesis of the Iulliminden basin karst (Niger). The carbonated and cuirass areas of the lulliminden basin plateaus show many closed-in, circular or oval depressions. Though noticed early by geologists, they have been described only recently. These depressions are similar to the known karstic forms such as dolines, ouvalas and poljes. Some of them, such as the valleys with bayonet-shaped lines and the karst with residual hillocks, are typical. The lithologie differences that characterize these plateaus make it possible to make assumptions on the origin of these pseudo-karstic forms : dissolution of limestones, sandstones (Continental terminal) and weathered rocks of the basement, and withdrawing.
Grottes fortifiées du Sabarthès (Ariège), une architecture castrale originale, XIIe-XIIIe siècles
Authors: Guillot Florence
Published: November 2018

Au sein des fortifications féodales construites dans le comté de Foix, on dénombre des grottes fortifiées qui sont construites à l'image des châteaux. Fortifications isolées dépendantes des comtes de Foix, elles caractérisent surtout la dynamique monumentale des XIIe et XIIIe siècles et s'inscrivent dans un mouvement géopolitique d'appropriation de l'espace par le pouvoir des comtes qui tend à devenir supérieur à celui des seigneuries locales. Elles s'intègrent dès lors dans un impressionnant glacis défensif dont la désuétude n'intervient pas avant la dernière décennie du XIIIe siècle.
Signification chrono-climatique de spéléothèmes laminés de Chine du Nord
Authors: Ming Tan , Tungsheng Liu , Xiaoguang Qin , Xianfeng Wang
Published: November 2018

De nombreux spéléothèmes de Chine septentrionale présentent des micro-lamines d'accroissement. La plupart de ces lamines possèdent des caractéristiques bi-optiques, observables en lumière fluorescente ou transmise. Les analyses hydrologiques et les datations radio-isotopiques démontrent que ces lamines sont annuelles. Une stalagmite holocène de la grotte Shihua, localisée au sud-ouest de Beijing, présente des milliers de lamines qui sont très similaires aux cernes de croissance des arbres. Les mesures d'épaisseur des lamines annuelles permettent de connaître les changements climatiques à court terme dans la région de Beijing pour les 1 130 dernières années.