bluuebunny/crossref_metadata_2025 huggingface dataset:
Cannabis and the liver: Things you wanted to know but were afraid to ask
Authors: Zhu Julie , Peltekian Kevork M
Published: February 2019

Many Canadians use cannabis for medicinal and recreational purposes. We describe the current understandings of how cannabis is metabolized in the liver and its potential interactions with other common drugs. We also summarize how cannabis may exert various effects in chronic liver diseases (CLDs), especially in chronic hepatitis C virus (HCV) and fatty liver disease.
Now You Hear It, Now You Don’t: Perception of English Regular Past –ed in Naturalistic Input
Authors: Strachan Lauren , Trofimovich Pavel
Published: February 2019

De précédentes recherches ont démontré que les formes régulières du passé des verbes anglais sont difficiles à percevoir. Or les chercheurs qui se sont intéressés à cette perception ont jusqu’à maintenant soumis leurs intrants à un traitement expérimental, la façon dont les indices contextuels, au-delà des adverbes de temps, influent sur la perception du passé régulier n’ayant pas retenu leur attention. Les auteurs se demandent si les apprenants de l’anglais langue seconde (L2) et les locuteurs natifs de l’anglais (L1) perçoivent le passé régulier – ed lorsque l’intrant s’inscrit dans un contexte naturaliste, si le rendu phonologique (marqué [әd] ou non marqué [t, d]) influe sur leur perception et si leur exposition à la langue et l’usage qu’ils en font sont liés à une confiance ou une justesse perceptuelle accrue. Dans le cadre de l’expérience menée par les auteurs, 11 locuteurs de la L1 et 28 apprenants de la L2 (14 de niveau intermédiaire et 14 de niveau avancé) ayant visionné 64 vidéoclips de comédies de situation télévisées (contenant 32 formes régulières du passé et 32 formes de base) ont indiqué s’ils entendaient ou non la terminaison – ed et ont noté leur degré de confiance sur une échelle de Likert à 8 points. Les apprenants de la L2 de niveau avancé ont perçu la terminaison – ed avec autant de justesse que les locuteurs de la L1, la performance de ces deux groupes s’étant révélée supérieure à celle des apprenants de niveau intermédiaire. Tous les participants ont perçu la terminaison [әd] avec plus de justesse que les terminaisons [t, d]. La confiance augmentait avec la maîtrise de la langue et diminuait avec la difficulté phonologique. La justesse de perception des apprenants en corrélation avec une mesure de l’exposition à la L2, ainsi que des entrevues, ont révélé des similitudes dans l’usage des indices du discours pour interpréter le temps chez les apprenants de niveau avancé de la L2 et les locuteurs de la L1. Les résultats de l’étude confirment que la perception de la terminaison – ed suppose l’interprétation de multiples indices contextuels.
Do Subnational Trade Agreements Reduce Trade Barriers? Empirical Evidence from Canadian Provinces
Authors: Beaulieu Eugene , Zaman Mustafa Rafat
Published: February 2019

As Canada faces threats to the global trading system, free trade between provinces within Canada remains elusive. Just as slow progress in multilateral trade negotiations has driven a proliferation of bilateral international trade deals, dissatisfaction with lack of progress federally has compelled Canadian provinces to sign bilateral agreements with other willing provincial partners. However, almost nothing is known about the efficacy of this approach. We use a gravity model to empirically investigate the effect of provincial agreements on interprovincial trade flows in Canada. We find that although most agreements facilitated trade between member provinces, others did not. We also find massive provincial trade barriers have declined by 15 percent over the past two decades in Canada.
Effects of Population Aging on Gross Domestic Product per Capita in the Canadian Provinces: Could Productivity Growth Provide an Offset?
Authors: Denton Frank T. , Spencer Byron G.
Published: February 2019

A shift in population distribution toward older ages is underway in industrialised countries throughout the world and will continue well into the future. We make use of a framework that we developed in earlier work to isolate the pure effects of population aging on per capita GDP in the 10 Canadian provinces and derive the rates of productivity growth required to offset those effects. For comparison, we consider also some changes relating to the supply of labour as possible alternative offsets.
Can Competition and Patent Policies Avert the Antibiotic Crisis?
Authors: Eswaran Mukesh , Gallini Nancy
Published: February 2019

Countries worldwide face an antibiotics health crisis. Resistant bacteria are rendering the current stock of antibiotics ineffective, and the pipeline of back-up drugs is running dry. Canada contributes more than its share to this global problem, with per-capita doses of antibiotics exceeding those of many of its peer countries in the Organisation for Economic Co-operation and Development. In a simple dynamic framework, we identify an efficient policy that reduces overuse and hence prolongs the lives of antibiotics. The policy includes (a) narrow patents to allow substitute drugs; (b) a flexible competition policy to permit limited coordination between competitors; (c) a regulatory standard on new substitute drugs to contain cross-resistance; and (d) a Pigouvian tax to reduce post-patent generic output. Complementing this patent-competition-regulatory-tax regime, additional incentives not dependent on sales, such as subsidies, prizes, and expedited regulatory reviews, may be necessary to promote development of new antibiotics.
La identidad de la arquitectura residencial multifamiliar contemporánea en Lima
Authors: Salas Juan de Dios
Published: February 2019

En años recientes, el intento de convertir en masiva la producción residencial inmobiliaria de Lima, por medio de la ampliación de las facilidades de acceso al crédito hipotecario, la publicidad, la germinación de una nueva psicología del consumo, las políticas gubernamentales en materia de vivienda, los cambios normativos de densidad, entre otros factores, ha generado una expedita y perceptible alteración del paisaje urbano limeño. Esta alteración del paisaje se evidencia en los procesos de rezonificación de usos del suelo de extensas áreas de Lima metropolitana y los consiguientes procesos de densificación.
Memoria, aceptación y replanteo. Avatares en la búsqueda de una posible identidad cultural en la arquitectura peruana
Authors: Castañeda César
Published: February 2019

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El acertijo de la arquitectura neogótica en el Perú y la antigua hacienda Unanue de Cañete
Authors: Negro Sandra
Published: February 2019

El Perú republicano de mediados del siglo XXI todavía se debatía politicamente en la incertidumbre propia de una república joven e independiente. El naciente estado se vio coyunturalmente involucrado en seis escenarios bélicos entre 1821 y 1866, los que ralentizaron su consolidación como nación. Estos tuvieron un costo social considerable e implicancias directas en el debilitamiento financiero subsecuente, aunque sin alcanzar el horizonte de cargas económicas abrumadoras. La explotación de nuevas e inimaginables riquezas no convencionales por entonces, generó un vuelco inesperado en la sociedad y finanzas decimonónicas. El aprovechamiento del guana y el cambio económico que este produjo, se debieron al aporte científico.
Arquitectura peruana: Entre la memoria, la identidad y la reinterpretación.
Authors: Guzmán Miguel
Published: February 2019

La noción de la arquitectura peruana implica el reconocimiento de su adjetivación y su calificación, en tanto categoría tangible que propone, por un lado, una producción edificatoria que va desde lo espontaneo a lo erudito desde lo ancestral hasta lo contemporaneo. Por otro lado, una mirada, un entendimiento o una reflexión y por consiguiente "una" narrativa que contruye un imaginario en busca de ciertas identifiaciones culturales.
Turismo y arquitectura interna
Authors: Romero Israel
Published: February 2019

La arquitectura, el turismo y el patrimonio son una trinidad que va de la mano y que se convierte en el principal argumento proselitista de los países y ciudades alrededor del mundo. Egipto, Roma, París e incluso Disneyland o Las Vegas no serían visitados por avalanchas de millones de emocionados niños, jovenes, adultos y ancianos cada año si no fuera por su arquitectura y, sobre todo, por edificios específicos. Es más, no serían lo que son si no fuera por su arquitectura, serían ciudades anónimas carentes del espectáculo que la arquitectura, cuando se vuelve turística e icónica, genera
Las Olvidadas plazuelas de la vieja iglesia de San Juan de Dios de Lima
Authors: Amorós Samuel
Published: February 2019

Las urbes virreinales solían tener una serie de pequeños espacios públicos anexos a las iglesias, que rompían la monotonía de una trama generalmente regular. Las dos plazuelas vecinas al antiguo templo juandediano de Lima componían un caso muy poco usual en la ciudad y al trascurrir el tiempo, fueron el escenario para violentos hechos históricos que marcaron la vida política peruana. Al desaparecer conjuntamente con toda la edificación religiosa, se borraron todos los recuerdos de su presencia, haciéndose necesario divulgar su historia para el presente y futuro de la sociedad.
La Defensa del patrimonio arquitectónico
Authors: Mardones Gabriela
Published: February 2019

Se entiende por patrimonio arquitectónico al conjunto de construcciones en las que cadasociedad reconoce un valor cultural y que considera debe ser protegido y conservado. Enel caso de Chile, este reconocimiento fue dado por primera vez a principios del siglo XX,cuando se determinó por ley la protección y conservación de ciertos edificios históricos.Desde aquel momento, la consideración del patrimonio arquitectónico ha sufrido diversastransformaciones, que han estado determinadas por los distintos valores patrimonialesatribuidos a los edificios por la sociedad en cada época. El presente artículo tiene por

objetivo reflexionar acerca del proceso histórico de la defensa del patrimonio arquitectónico,uniendo el pasado al presente, para lograr una mejor aprehensión del futuro próximo, elúnico sobre el cual podríamos tener algunas posibilidades de acción.
Ciudad Deportiva de Boca Juniors
Authors: Santaló Claudia Berta
Published: February 2019

En este artículo se indaga sobre los lugares perpetuados por la memoria popular que noson reconocidos oficialmente y que sin embargo revisten un alto valor simbólico para unadeterminada comunidad. Tal es el caso de la Ciudad Deportiva de Boca ubicada en la costanera

sur de la ciudad de Buenos Aires, Argentina, que en la década de los 60 del siglo XX se constituyó

no solo en un sitio de concentración y esparcimiento popular sino también en un proyecto y sueño

colectivo alrededor de uno de los clubes de fútbol más importantes del país. De aquella Ciudad

Deportiva hoy solo quedan ruinas y un proyecto privado de desarrollo inmobiliario. Sus cambios

en el tiempo muestran la ineludible relación de los espacios con los procesos políticos.
Accrual Effect on Karachi Stock Exchange
Authors: Awan Zaheer Abbas , Kashif Muhammad , Ur Rehman Muhammad Waseem
Published: February 2019

The study examine whether the stock prices can reflect the information of future earnings contained in the accrual components of the current period. The magnitude of accruals component determines the extent to which the current earnings performance persists in the future. However, the current earnings show that the investors hardly reflect the information contained in the accruals components. All listed and non-listed companies (662) on Karachi Stock Exchange, form January 1993 to December 2015 are incorporated in the study. The study concluded that accruals anomaly does not exist in the Karachi Stock Exchange. Which implies that an investor who follows an investment strategy on the basis of accruals will not earn excess returns. Moreover, it implies the Capital Asset Pricing Model is a valid model to capture the effect of accruals.
Asset Growth Anomaly and Stock Returns: An Evidence of Karachi Stock Exchange (KSE) Market
Authors: Shaikh Asra Jawed , Kashif Muhammad
Published: February 2019

In efficient market, firms who make more investments are considered to have high earnings and better prospects which instantly incorporated into its share prices. However, range of studies demonstrated sturdy evidence of asset growth effect i.e.“Higher returns have been enjoyed by low growth firms and vice versa” and claims this factor explains returns better than market beta of various asset pricing models (Cooper, Gulen & Schill, 2008; Li & Sullivan, 2014 and Wen, 2014). Hence, this study is an attempt to explore the profitability of asset growth anomaly on Karachi Stock Exchange (KSE) by constructing deciles portfolios from Jan 2001-Dec 2015. The results support the existence of asset growth anomaly in KSE market. The use of Generalized Methods of Moments (GMM) proved that Capital Asset Pricing Model (CAPM), Fama-French (three and five factor) models are mis-specified models in case of KSE because they all botched to elucidate the cross sectional variation in portfolios returns based on firm’s asset growth. The results of current study are highly consistent with the Fama & French (1993, 2015). The empirical findings recommends investing in small growth firms is an appropriate sound strategy to generate abnormal higher returns as we claim stocks can be predicted on the basis of asset growth anomaly and through developing this investment strategy i.e. by taking the long position in low growth stocks and short position in high growth stocks, investors may generate positively higher returns in Pakistan
Perioperative infusion therapy in children
Authors: Dmytrіiev Dmytro , Starodub A I
Published: February 2019

This article is devoted to the questions of infusion therapy – a method of treatment, which gives the possibility of parenteral administration of various substances and medicines into the body and directions for the promotion of basic functions and bio-chemical processes in the body. We considered the organization of conducting adequate infusion therapy in a particular patient, with a specific clinical situation, the questions of the purpose and tasks of infusion therapy now and in the future (tactics and strategy), the means that will be applied, their type, volume, quantitative and qualitative correlation, ways of introduction, speed and duration of the general and, if necessary, of the skin volumetric component, methods for controlling effectiveness and safety. In addition, the issues of physiological and pathological and physiological processes taking place in the child’s body and the justification of the use of different methods of infusion therapy for effective and safe infusion therapy in the child are considered.
Comparison of Extended Education and Research in this Field in Taiwan and in Switzerland
Authors: Schuepbach Marianne , Huang Denise
Published: February 2019

During the past two decades, there is a global growing interest in the field of extended education. Countries in both the East and the West alike have been investing in developing systems to support student learning after the traditional school hours. This paper examines the similarities and differences in this trend of development in Taiwan and Switzerland. Cultural influences, the beliefs and values of these countries, and the importance of contextualization in comparative education are discussed.
Physicochemical characteristics and polyphenolic compounds of cultivated blackberries in Costa Rica
Authors: Soto Marvin , Pérez Ana M. , Cerdas María del Milagro , Vaillant Fabrice , Acosta Óscar
Published: February 2019

BACKGROUND:

Blackberry fruits have recently gained attention because of their considerable amounts of polyphenols.

OBJETIVE:

The aim of this study is to compare the physicochemical composition and contents of the main polyphenolic compounds of nine tropical highland blackberry genotypes grown in Costa Rica, and to evaluate the effect of environmental conditions and farming practices on physicochemical composition of fruits of ‘Wine red thorn’, which is the most widely grown blackberry genotype in Costa Rica.

METHODS:

Nine blackberry genotypes were harvested at fully ripe stage. Environmental conditions (geographic location and harvest season) and farming practices (organic and conventional techniques) were evaluated to determine their effects on physicochemical composition and polyphenolic compounds of ‘Wine red thorn’ blackberries. Anthocyanins and ellagitannins contents were determined by HPLC-DAD.

RESULTS:

The tropical highland blackberries contained appreciable levels of polyphenols. Anthocyanin content ranged from 2.9±0.1 to 12±1 g cyanidin-3-glucoside equivalents/kg dry weight (DW); ellagitannin content ranged from 9.3±0.8 to 47±3 g ellagic acid equivalents/kg DW. The influence of environmental conditions and farming practices on physicochemical characteristics of ‘Wine red thorn’ blackberries was significant ( p < 0.05). Blackberries harvested during the dry season had higher contents of sugars and anthocyanins than blackberries harvested during the rainy season. Organic blackberries had higher levels of ellagitannins than conventionally grown fruits.

CONCLUSIONS:

These data prove that Costa Rican blackberries are a good source of polyphenolic compounds, especially ellagitannins. Environmental and farming conditions can be exploited to obtain high quality blackberry fruits.
Postharvest exogenous melatonin treatment of strawberry reduces postharvest spoilage but affects components of the aroma profile
Authors: El-Mogy Mohamed M. , Ludlow Richard A. , Roberts Callum , Müller Carsten T. , Rogers Hilary J.
Published: February 2019

BACKGROUND:

Strawberries are perishable fruits that decay quickly after harvest, but are valued for their distinctive taste and aroma. Melatonin is involved in plant resistance against stress, plant senescence and fruit ripening, and was shown to delay post-harvest spoilage of strawberries.

OBJECTIVE:

The effects of melatonin postharvest treatment on shelf-life and volatile organic compound profile were assessed in strawberry fruits cv “Luca”.

METHODS:

Strawberry fruit were treated with 100 μM melatonin and stored at 4°C for 12 days to assess whether melatonin treatment could delay spoilage without adversely affecting aroma.

RESULTS:

Melatonin treatment delayed fruit deterioration by reducing weight loss and incidence of decay as well as maintaining total soluble solids, titratable acidity, anthocyanin, and taste. Melatonin treatment also significantly reduced CO2 production compared to control fruits. The relative abundance of the majority of volatile organic compounds (VOCs) was not affected, however abundance of two VOCs that are important components of strawberry aroma were affected by melatonin treatment.

CONCLUSIONS:

Post-harvest treatment of strawberries with 100 μM melatonin improved strawberry quality and conserved bioactive compounds after 12 d of storage. However, components of the aroma profile were altered in a way which may affect consumer perception of quality.
The effect of omega-3 supplementation on glycemic indices and lipid profile in type 2 diabetic patients with non-alcoholic fatty liver disease: A double-blind, randomized, clinical trial
Authors: Orang Zahra , Mozaffari-Khosravi Hassan , Sivandzadeh GholamReza , Pantovic Ana
Published: February 2019

INTRODUCTION:

Serum phospholipid omega-3 fatty acid levels in patients suffering from both type 2 diabetes (T2DM) and non-alcoholic fatty liver (NAFLD) are lower than in their healthy counterparts. Omega-3 supplementation can be effective in controlling glycemic indices in T2DM, and in improving lipid profiles in T2DM and NAFLD as well. The aim of this study was to evaluate the effects of omega-3 fatty acid supplementation on glycemic control and lipid profile in patients with T2DM and NAFLD.

METHODS:

In this randomized double-blind placebo-controlled clinical trial, 60 patients with T2DM and NAFLD were enrolled. The participants were randomly divided into two groups. The omega-3 group (OG) received capsules containing omega-3 fatty acids (2g/d), and the placebo group (PG) received placebo capsules (2g/d) during a12 week period. Dietary intake was assessed with 24-hour dietary recalls. Fasting blood samples and anthropometric measurements were collected at the baseline and after 12 weeks. Serum levels of glycemic indices (fasting blood glucose (FBG) levels, glycosylated hemoglobin (HbA1c)) and lipid profile (levels of triglyceride (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-c) and high density lipoprotein cholesterol (HDL-c)) were measured.

RESULTS:

Fifty-six patients completed the study. Paired t- test revealed no significant differences in the baseline measurements between the two groups. At the end of the study compared with the PG, the OG had a significant reduction in serum TG levels. However, there was no significant effect of omega-3 supplementation on the other parameters: the mean FBG or HbA1c concentration, neither on TC, LDL-c and HDL-c levels.

CONCLUSION:

Two grams per day of omega-3 supplementation after 12 weeks led to a significant reduction in serum TG levels in patients with T2DM and NAFLD. However, no significant effects were observed on FBG, HbA1c, TC, LDL-c, and HDL-c levels.
HISTORY OF USE OF MARKETING COMMUNICATIONS IN SPHERE OF MOTORSPORT
Authors: Kulinchenko M.I.
Published: February 2019

The purpose of this work is to study the development of marketing communications in the field of motor sports and to establish the periodization of their development. The methodological base was made up of an analysis, as well as a historical method. Having studied the changes in marketing communications in this industry since the beginning of the birth of motor sport in 1894 to the present, features of marketing communications of this sphere were singled out, according to which their development was divided into three periods. The results of this study help to better understand the development of marketing in the field of automobile competitions, taking into account their specific characteristics, and also to predict their development trends.
THE PROBLEM OF SOCIALIZATION OF YOUTH IN CRISES TRANSITION
Authors: Antonova E.L. , Turkina V.G.
Published: February 2019

The article deals with the problem of self-realization of young people in a permanent crisis. We are talking about youth subcultures, which consist of those who "dropped out" from society or are in an uncertain (liminal) state of transition from one social group (youth) to another (adults), which creates a serious problem for the socialization of young people. In these circumstances, young people are faced with the urgent need to build their own "counterculture", while playing specific roles that do not coincide with the interests of the majority. And although the liminal state of youth self-determination has become a real disaster for the West itself, it continues to be presented to the world community as an achievement of modern Western culture, the main postulate of which is the free choice of the individual.
APPLICATION OF GENETIC ALGORITHM OF OPTIMIZATION DURING THE PROCESS OF URBAN PASSENGER TRAFFIC MANAGEMENT
Authors: Lekveishvili G.A. , Gogiashvili P.G. , Chogovadze J.T. , Kbilashvili D.G.
Published: February 2019

The paper proposes a generalized logistic model of the urban passenger transportation system, and on its basis, there has been developed a modified model that allows for determining a set of organizational and economic indicators in each state of a system. To solve the optimization problem of the transportation process system under conditions of dynamically changing passenger traffic flows, there has been justified searching for a balance between the effectiveness and quality of solutions due to the «survival of the strongest alternative solutions» y to earn system of operational control buses on the route. There has been proven the advantage of using genetic algorithm to optimize the processes of organizing and managing the system of urban passenger transport with the aim of maximizing the profits of an enterprise at minimal cost.
JUSTIFICATION OF RISK MANAGEMENT IN VIRTUAL SECURITIES TRANSACTIONS
Authors: Sokolovsky M.V. , Tselikhina I.V.
Published: February 2019

The article explores the specific risks that accompany online securities transactions. Private investors are focused on speculative operations, long-term investments are unpopular. This increases the risk and forms the need for risk management. The article attempts to analyze the risk management system of virtual work of Internet brokers on the stock exchange. The emphasis has been shifted specifically to private investment, since this block is one of the most promising for the development of the securities market at the present stage. The purpose of risk management in the system of Internet trading in securities is positioned in the article, primarily as a reduction of financial losses, and then ensuring the financial stability and reliability of the system for the client.
FORMING THE IMAGE OF A SOVIET ENEMY: A STUDY OF THE AMERICAN PRESS AND OFFICIAL DOCUMENTS OF THE BEGINNING OF THE COLD WAR
Authors: Shamatova Yu. Yu.
Published: February 2019

The article is devoted to a review of materials of the American press and official documents of the White House in 1946-1953-ies. The focus is on analyzing the techniques and methods used in periodical and daily publications to construct a negative image of yesterday's ally in the person of the Soviets. Informational and ideological indoctrination of the population affected not only the adult population, but also the younger generation. For this purpose, various comics were created, cards that contained information about the approaching threat from the USSR. As a result, by the early 1950s the state apparatus managed to radically change public opinion: the positive image of the Soviet Union in the eyes of Americans was replaced by skepticism about the future relations of the superpowers and confidence in the new war to cleanse the world of the "red plague".
ONTOGENETIC STRUCTURE AND ASSESSMENT OF POPULATIONS OF THYMUS KRYLOVII BYCZENNIKOVA IN MINUSA DISTRICT OF THE KRASNOYARSK TERRITORY
Authors: Filimonova A.L.
Published: February 2019

The article presents the results of the study of ontogenetic structure and assessment of the state of coenopopulations of Thymus krylovii Byczennikova in steppe plant communities of Minusinsk district of Krasnoyarsk region. It was found that the ratio of individuals of different ontogenetic groups studied coenopopopulations normal, also incomplete. Ontogenetic spectra of the studied right-hand type cenopopulations with a maximum on individuals in the old generative ontogenetic state. According to the "Delta-omega" classification, the studied cenopopulations are aging. The obtained results on the developmental biology, ontogenetic structure and values of the main demographic indicators characterize the coenopopulations of Thymus krylovii Byczennikova as unstable. To evaluate the stability of populations in the study region. It is shown that their optimal state is achieved in these fine-grained steppes. Optimum is achieved mainly due to population characteristics.
TO THE PROBLEM OF THE LEGAL NATURE OF STRIKING OFF THE REGISTER
Authors: Kareva I.D.
Published: February 2019

This article is devoted to the research of theoretical and practical aspects of the procedure of striking off the Register. The article shows the fundamental bases for striking off the Register, the striking off procedure, the law-enforcement practice and conclusions about the legal nature of striking off the Register of legal entities.
MECHANISMS AND CLINICAL SIGNIFICANCE OF NEPHROPROTECTIVE ACTION OF SODIUM-GLUCOSE COTRANSPORTER 2 INHIBITORS
Authors: Pchelin I.Y. , Vasilkova V.N. , Shishkin A.N. , Bayrasheva V.K. , Hudiakova N.V.
Published: February 2019

The issue of mechanisms and clinical significance of nephroprotective action of sodium-glucose cotransporter 2 (SGLT2) inhibitors is dealt with. Discussed are the manifestations related to the following effects of the members of this pharmacological group: their influence on glomerular filtration rate, glycaemia, diuresis, ketogenesis and other factors. The results of recent experimental and clinical studies revealing particular aspects of nephroprotective action of SGLT 2 inhibitors in type 2 diabetes mellitus and other pathological conditions are analyzed.
CREATING PROFESSIONALLY ORIENTED TASKS OF COMMUNICATIVE NATURE: FROM TEACHING EXPERIENCE
Authors: Pasechkina T.N.
Published: February 2019

The article draws attention to some aspects of creating professionally oriented tasks in the context of the formation of future specialists’ communicative self-efficacy. The recommendations presented are based on the analysis of theoretical and methodological literature, as well as taking into account the author’s own experience. The article is addressed to teachers interested in using professionally oriented tasks in the practice of working with students.
EVALUATION OF FORMATION OF LEGAL CULTURE IN THE EDUCATIONAL ENVIRONMENT BOARDING SCHOOL
Authors: Alexandrova S.N.
Published: February 2019

The article deals with the problem of organization of the process aimed at the education of orphans to the culture of law in the space of boarding school. The results presented in this article - theoretical analysis and study of scientific approaches of teachers and scientists evaluation indicators of legal culture, development and scientific justification of criteria to measure the components of legal culture in orphans and children left without parental care. The methodological basis consists of system, personal, cultural, activity, polysubject (dialogical) approaches to the study of social and pedagogical phenomena; pedagogical ideas of humanization of education. As research methods used, empirical-observation, individual and group conversations, interviews, questionnaires, testing, study of school documentation (personal files of students, class journals, minutes of meetings, meetings) and pedagogical experiment; theoretical - analysis of philosophical and pedagogical literature. To determine the level of legal culture, the optional legal culture of the individual was introduced. Activity approach to the study of the concept of legal culture allowed to develop evaluation and criteria tools of levels of formation of legal culture of orphans and children left without parental care. Taking into account the analysis of the main approaches to the study of levels, indicators and criteria at the theoretical level, the article also presents the author's approach to the method of determining the criteria, indicators and levels of formation of legal culture in the educational space of the institution for orphans and children left without legal culture at the practical level. Criteria, indicators of formation of legal culture which are introduced and tested in educational process of boarding school are scientifically proved and developed. The proposed criteria and indicators can be used in various types of educational institutions to assess the level of education of legal culture of young people.
ANARCHISM AND ECOTECHNOLOGY
Authors: Saimiddinov A.K.
Published: February 2019

The article addresses the issue of the role and purpose of technology in the modern discourse of eco-anarchism. The author examines the concepts of Murray Bookchin and John Zerzan in order to reactivate the need for understanding the technology regarding the current global environmental and social crises of the Anthropocene. The technology in eco-anarchism cannot be freed from the socio-ethical moment, therefore any questioning about technology is connected with understanding its relations with society and nature. Opposing Marxism, eco-anarchists see in technology not so much a way of exploitation of the environment by a man as an active embodiment of ecological symbiosis between society and nature. Such an interpretation of the technology allows us to rethink the essence of both the work activity of the person and the power relations in society.
Categorizing Molecular Features of NOTCH4 Involved in Breast Cancer
Authors: Sinoorkar Vinod P. , Pagul Shrutika S.
Published: February 2019

Breast cancer is one of the leading causes of cancer death in women. It is observed that hormonal, lifestyle and environmental factors that may increase the risk of breast cancer and often begins with cells in the milk-producing ducts (invasive ductal carcinoma), glandular tissue called lobules (invasive lobular carcinoma) or in other cells or tissue within the breast. The major signaling pathways involved in the breast cancer are Estrogen pathway, MAPK signaling pathway, PI3K/AKT signaling pathway, Notch signaling pathway, Wnt signaling pathway and P53 signaling pathway. Over the past decade, abnormal activation of Notch signaling in breast cancer has been stated by many different groups. In invasive breast cancer, the elevated expression of Notch signaling pathway components has been reported, including Jagged1-2, Dll1, Dll3, and Dll4, Notch receptor (Notch1 to Notch4). It is observed that increased JAG1-NOTCH4 signaling in human breast tumors is an important stimulator of cancer stem cells. The present investigation deals with the thorough understanding of molecular features of NOTCH4 protein emphasizing its key role in triggering the cancer pathway, by using different bioinformatics tools. The detailed insights into molecular features and the functional elements of NOTCH4 by analyzing its physicochemical parameters, secondary and tertiary structure prediction, domain analysis and intermolecular interactions, it can be considered as one of the potent drug target in breast cancer and can contribute to a novel alternate and promising treatment strategy for breast cancer through computer aided drug designing.
Identifying the Most Critical Factors to Business Intelligence Implementation Success in the Public Sector Organizations
Authors: I. Magaireah Asma , HidayahSulaiman HidayahSulaiman , Ali Nor’ashikin
Published: February 2019

The BI is a new trend in public sector organizations that requires investigating the critical success factors (CSFs) which would provide a sound guidelines for determining the criteria to be considered during BI implementation. However, there is no sufficient empirical evidences that provide better understanding of the CSFs for the BI implementation in public sector organizations. This paper aims to identify the CSFs for BI system in the context of public sector organizations. This study adopts a mixed method approach using survey research method and qualitative interview using Jordanian public sector organization case. The findings of this research revealed that top management support, clear vision and strategic planning, team skills, user participation, organizational structure, user access and development technology are the most critical factors to BI implementation success in the public sector organizations. The findings of this study could assist the practitioners in the public sector organizations in planning, managing and implementing their BI projects properly by focusing on those CSFs of BI systems that provide them a better understanding to address issues and concerns related to BI implementation.
ENTRE O MUNDÃO E A CASA: A PASSAGEM PELO CENTRO DE ATENDIMENTO SOCIOEDUCATIVO AO ADOLESCENTE - FUNDAÇÃO CASA E A APROXIMAÇÃO AOS CÓDIGOS DO SISTEMA PRISIONAL
Authors: GONÇALVES Rosângela Teixeira
Published: February 2019

Analisa o perfil, a trajetória e as representações dos jovens egressos das unidades socioeducativas da Fundação CASA, sobre o período de cumprimento da medida de internação e da medida socioeducativa em meio aberto de liberdade assistida. Como conclusões, a pesquisa destaca que, para os sete jovens entrevistados, egressos das unidades da Fundação CASA, a medida socioeducativa de internação vem sendo compreendida enquanto pena e as unidades socioeducativas, como prisão. Na primeira passagem os jovens passam a incorporar em seu vocabulário uma linguagem nativa das penitenciárias para referirem-se aos seus atos infracionais, ao cumprimento da medida, a diferenciar a instituição do mundão e a valer-se das normas e dos procederes do Primeiro Comando da Capital. Desse modo, quando em liberdade, a medida socioeducativa de internação amplia o status positivo dos jovens frente ao crime e o status negativo frente à instituição escolar e ao mundo do trabalho.
POLÍTICAS PÚBLICAS PARA A FORMAÇÃO DE PROFESSORES: UMA EXPERIÊNCIA DE ENSINO JUNTO AO PROGRAMA INSTITUCIONAL DE BOLSAS DE INICIAÇÃO À DOCÊNCIA (PIBID)
Authors: FILGUEIRA Ana Maria Falcão , MARTINO Vânia De Fátima
Published: February 2019

O Programa Institucional de Bolsa de Iniciação a Docência (PIBID) foi criado em 2007 pelo Ministério da Educação e implementado pela CAPES/FNDE com a finalidade de valorizar o magistério e aproximar os estudantes ainda na graduação com o ambiente escolar. O projeto foi instituído na Faculdade de Filosofia, Ciências e Letras de Ituverava (FFCL), no ano de 2012, com a proposta de seis subprojetos de licenciaturas: Matemática, Pedagogia, Ciências, Letras, História, e a inclusão do interdisciplinar que é composto por alunos de Pedagogia e História. O objetivo deste trabalho é apresentar um relato de experiência de ensino de Ciências realizado pelos bolsistas participantes do Programa abordando de forma ampla a temática da formação dos professores e sua relação direta com as políticas públicas educacionais no Brasil. Desta forma, este trabalho perpassará, de forma sucinta por programas instituídos pela Nova Capes, Programa de Consolidação das Licenciaturas (Prodocência), Programa Institucional de bolsas de Iniciação a Docência (PIBID), Programa Observatório da Educação (Obeduc) e o Plano Nacional de Formação de Professores da Educação Básica (Parfor), que oferecem formação inicial e continuada aos professores da educação básica. O intuito não é de relatar experiências vivenciadas através destes programas, mas sim evidenciar a relevância que têm para a formação e capacitação de professores. Tanto o relato quanto a abordagem do tema levou em consideração que as políticas públicas para formação de professores devem atingir o interesse das universidades, para que estas promovam parcerias com as escolas.
APRESENTAÇÃO
Authors: CASTRO Rosane Michelli de
Published: February 2019

Mais uma vez, apresentamos mais uma Edição da Revista do Instituto Políticas Públicas de Marília, em cumprimento aos objetivos que deram início a sua produção e a sua circulação, objetivos esses centrados na possibilidade de fazer dessa Revista um espaço de disseminação do conhecimento gerado, por meio e a partir de projetos, serviços e atividades relacionados às políticas públicas.
Anomalous Properties of Some Fluids − with High Relevance in Energy Engineering − in Their Pseudo-critical (Widom) Region
Authors: Imre Attila R. , Groniewsky Axel , Györke Gábor , Katona Adrienn , Velmovszki Dávid
Published: February 2019

Recent results are shown about the peculiarities of the pseudo-critical region, with special emphasis on properties important for energy production and conversion. The property-map of some materials, which are relevant as model fluids or as working / cooling fluids in energy engineering (argon, methane, water and carbon dioxide) and their relative positions to various adiabats – influencing their stability through the anomalous properties – are presented. Some potential technological problems related to the existence of these anomalies are discussed.
Islamic Symbols on Political Messages in Newspapers in Riau (Study in Regional Head Election 2017)
Authors: Riauan Muhd Ar. Imam , Kholil Syukur , Sikumbang Ahmad Thamrin
Published: February 2019

: This study seeks to find the process of constructing Islamic symbols in the political message of newspapers in Riau. The symbol of Islam in question is a symbol of Islam exposed by newspapers in Riau during the campaign of the regional head election of Pekanbaru City starting from October 26, 2016 to February 11, 2017. The theory used in this study is social construction theory, by Peter L .Berger and Thomas Luckmann. Peter L.erger who at the beginning of his development, this theory is a constructivist study in sociology to understand the interactions created by individuals as members of society in a continuous manner becomes a reality that is experienced together in social life. This research uses a constructivist approach to understand how the process of constructing Islamic symbols in political messages. The subjects of this study were 5 candidates for regional head of Pekanbaru City who were actively exposed by the media and used Islamic symbols in various campaign activities during the Campaign from 26 October 2016 to 11 February 2017. The object of the research was the construction of Islamic symbols exposed to newspaper in Riau. The results of this study indicate that the construction process is divided into two, namely the construction process that occurs because it is caused by the process of finding data and facts about the needs of the community and the construction process that appears as the identity of prospective regional heads.
Factors that Influence the Reality of Performance Accountability in Government Institutions (Empirical Study in Government Deli Serdang District)
Authors: Syahputri Yuni , Bilqis R May Hana , Dalimunthe Hasbiana , Sabrina Hesti , Rahmadhani Sari Nuzullina
Published: February 2019

This study aims to determine whether the commitment of management, decision making authority, organization culture is partially affected and simultaneously to the accountability performance in government agency to improve government performance. This research method is to use a casual research design. The sample is determined by using the technique of purposive sampling.The population in this research are all employees of the Unit of work Tools (SKPD) Government of Deli Serdang. The sample used in this study is structural officials (Echelon 2, 3 and 4), with a total sample of 60. The data in this study is the primary data obtained from questionnaires distributed directly to the respondent. Data analysis model used was multiple linier regression. Testing the quality of data used is the test validity and reability testing. Classic assumption test was used for normality test, test heterokedastisitas, and tes multikolinearitas. Hypothesis testing using the determinant coefficient, simultaneous test (test-F), partial test (test-t).The results show that management commitment partially has a positive influence on performance accountability. Decision making authority partially has a positive influence on performance accountability. Organization culture partially has a positive influence on performance accountabilitypartially has a negative influence on performance accountability. Simultaneously commitment management, decision making authority, organization culturehave a positive and significant influence on performance accountability.
PARAMETER EVALUATION OF CARDIOVASCULAR SYSTEM IN SCHOOLCHILDREN UNDER THE CONDITIONS OF LATITUDINAL DISPLACEMENT
Authors: Filatova D Yu , Bashkatova Yu V , Filatov M A , Ilyashenko L K
Published: February 2019

In the conditions of Russian North recreation activity is usually carried out by means of latitudinal displacement from North to South and realization of health-related activity. Herein a regular question about of their effectiveness arises. Tradition statistic methods of parameter evaluation of the cardiovascular system (CVS) homeostasis of a person, in this case, show poor efficiency; often they do not show differences between the organism's state before and after the treatment. The aim of the research was to study the effect of latitudinal movements on the process of functional systems changes of children's organisms. Information on the indices state of cardiovascular system of schoolchildren was acquired by the method of pulseintervalography on the basis of the pulse oximeter "EL0KS-01". The CVS parameters of schoolchildren were analyzed in the process of latitudinal displacement (from north to south of the Russian Federation and vice versa). The result of the study showed that a two weeks' vacation in the south reduced the quasi-attractors' size of the vector state of children's organisms in the six-dimensional phase space of states (m = 6) and partially normalized the indices of their cardiorespiratory system. The volume of quasi-attractors (m = 6) after returning to Surgut decreased 2,3 times in boys and 4,7 times in girls in comparison with the state before leaving to the south. However, the reaction in girls was more expressed and persistent than in boys, who showed a partial return to their original state (before departure) after their return from the south. In fact, girls show an exponential decrease of quasi-attractors volumes, and boys - a parabolic type depending on VG from the type of stay (registration). Similar dynamics was observed in age-related changes of quasi-attractors volumes of cardiointervals of Khanty women (decrease in volumes with age) and newcomers (they had a parabola for quasi-attractors of cardiointervals). Conclusion: calculation of the parameters of CVS quasi-attractors shows a significant difference in all diagnostic parameters from the results of statistical processing of primary data.
COMPARATIVE INDICATORS OF IRON AND MANGANESE CONTENT IN THE HAIR OF WOMEN LIVING IN THE NORTHERN REGION WITH DIFFERENT TREATMENT OF DRINKING WATER
Authors: Korchina T Ya , Minyailo L A , Safarova O A , Korchin V I
Published: February 2019

Aim: to study the concentration of Fe and Mn in the hair of women living in the cities of Khanty-Mansiysk Autonomous Region (KHMAO) with different treatment of drinking water. Methods. The ultimate composition of hair of 106 women (average age 38,9+11,3 g) - residents of the Northern region, not employed in the manufacturing sector was studied. 50 of them lived in the cities of Nefteyugansk and Nyagan and 56 - in the cities of Surgut and Khanty-Mansiysk. In the cities of Surgut and Khanty-Mansiysk underground water undergoes non chemical treatment, iron removal by the method of deep aeration and decontamination on UV irradiation installations. In the cities of Nefteyugansk and Nyagan water from artesian wells is decontaminated only by baclor. Results. The women living in the cities of Nefteyugansk and Nyagan had significantly higher (p < 0,001) and higher than reference values of Fe (82,3 + 11,4 mkg/g - the norm 7-40) and Mn (11,3 + 1,9 mkg/g - the norm 0,15-2,0) concentrations in the hair compared to women living in cities with high-quality purification of drinking water: Fe (23,6 + 2,2 mkg/g) и Mn (3,1 + 0,2 mkg/g). Iron, getting in to the organism with other pollutants (dietary Fe excess is not negative) also shows the properties of the immunosuppressant. Manganese is considered to be vital and at the same time a toxic element with mutagenic activity and tendency for accumulation. We can assume the best resistance to the adverse effects of oxidative stress in women-residents of KHMAO cities with optimal treatment of drinking water. Conclusions: To correct the microelement status of the Northern region population it is necessary to carry out more research of the environmental objects (in particular water) on the content of heavy metals, pay special attention to quality control of drinking water, and to use the method of microelement status determination of the hair chemical composition as an additional method of assessment of the internal body environment.