bluuebunny/crossref_metadata_2025 huggingface dataset:
MENINGKATKAN MINAT BACA PESERTA DIDIK MELALUI METODE QUANTUM READING DALAM MATA PELAJARAN BAHASA INDONESIA
Authors: Kuraesin Imas Nenden , Suryana Nana , Munggaran Nita Anjung
Published: December 2020

This research is based on findings in the field, namely students' low interest in reading, no initiative to read books, less reading activities, and less supportive library facilities.

 The formulation of the problem in this study is how to increase the reading interest of students who use quantum reading methods and conventional methods in Indonesian language subjects at Pakemitan 2 Public Elementary School. This study aims to determine the increase in reading interest of students who use quantum reading methods and conventional methods in Indonesian language subjects at Pakemitan 2 Public Elementary School.

 The research method used is the experimental method with the Nonequivalent Control Group Design form. The population used was 165 students, and two sample classes were class IV as a control class totaling 28 students and class V as an experimental class totaling 35 students. Research data was collected through questionnaires with statistical analysis. Analysis of the data used is normality test, homogeneity test, and hypothesis testing using SPSS version 24.0 for windows.

 The results of the analysis of variable X, it is known that the control class pre-test value obtained an average value of 53.92 is in the low classification, and the experimental class pre-test value obtained an average value of 55.94 is in the low classification. As for the value of the post-test control class obtained an average value of 58.46 in the low category, this shows the implementation of the conventional method has not been successful, and the post-test value of the experimental class obtained an average value of 67.34 in the category quite effective, this shows the implementation of the quantum reading method is quite successful. The results of the variable analysis Y, it is known that the control class pre-test value obtained an average value of 55.07 is in the low classification, and the experimental class pre-test value obtained an average value of 55.57 is in the low classification. As for the value of the post-test control class obtained an average value of 60.03 in the low category, this shows the implementation of the conventional method has not been successful, and the post-test value of the experimental class obtained an average value of 68 in the category quite effective, this shows the implementation of the quantum reading method is quite successful, then Hₒ is rejected or Hₐ is accepted. That is, the use of the quantum reading method can increase the reading interest of elementary school students in Indonesian subjects.
Pemikiran Deliar Noer Mengenai Gerakan Islam Modern Indonesia 1900-1942
Authors: Iskandar Irpan , Firdaus Dede Wahyu
Published: December 2020

Deliar Noer adalah seorang ilmuwan bidang politik dan sejarah Islam di Indonesia abad ke-20. Pemikiranya mengenai gerakan modern Islam Indonesia 1900-1942 telah memberikan sumbangsih keilmuan dan menjadi rujukan studi Islam di Indonesia Penulisan artikel ini bertujuan untuk menganalisis pemikiran seorang Deliar Noer dalam bukunya yang berjudul “Gerakan Islam Modern Indonesia 1900-1942”. Metode yang digunakan dalam artikel ini yaitu menggunakan metode penelitian literature review. Hasil penelitian menunjukan bahwa; (1) awal gerakan Islam modern muncul dari pengaruh para ulama yang belajar ke Timur Tengah, hingga pemikiran-pemikiran Islam modern ini menyebar ke berbagai daerah di Hindia Belanda dengan metode keorganisasian, pendidikan, dan pers. (2) Gerakan Islam modern di Indonesia dapat dibedakan atas gerakan sosial pendidikan, politik, dan ekonomi. (3) perkembangan gerakan Islam modern mengalami dinamika dan reaksi yang muncul baik dari pemerintah kolonial Belanda, kalangan Islam tradisional, maupun kalangan kebangsaan dan nasionalis.
YOUNG, F. A HISTORY OF EXORCISM IN CATHOLIC CHRISTIANITY. CAMBRIDGE: PALGRAVE MACMILLAN, 2016.
Authors: Busch Willian Perpétuo
Published: December 2020

Resenha
“IRRADIAR O SOPRO DO ESPÍRITO SOBRE O MUNDO”: REPRESENTAÇÕES DA PESQUISA SOCIOLÓGICA NO CATOLICISMO CARISMÁTICO
Authors: Silva Emanuel Freitas da
Published: December 2020

O estudo do fenômeno religioso, em suas diversas dimensões, exige o esforço de compreensão, por parte do pesquisador, das dinâmicas e nuances próprias do universo pesquisado. A começar pela definição do que o campo em análise considera como religioso, as formas de defini-lo e experenciá-lo, laços identitários e relacionais nele engendrados, léxico próprio ao campo e, mesmo, os significados do seu trabalho epistemológico para os sujeitos pertencentes ao universo pesquisado. Tomando como córpus de análise o universo da Comunidade Católica Shalom, sediada em Fortaleza (CE), o artigo tem como objetivo discutir nuances da pesquisa em meio religioso, destacando dois aspectos considerados fundamentais: a identificação do conceito-chave para a compreensão do campo e as representações produzidas pelos atores do campo acerca da pesquisa realizada, os fazendo produzir uma certa episteme êmica acerca do saber sociológico que se buscava produzir sobre eles. Por meio da discussão teórica-êmica acerca do termo “carisma” e da análise dos sentidos que os sujeitos deram ao ato de pesquisar elabora-se, aqui, uma reflexão sobre as dinâmicas da pesquisa em meio religioso.
Risk Factors for Increased Consumption of Narcotics After Hip Arthroscopy: A Prospective, Randomized Control Trial
Authors: Selley Ryan S. , Hartwell Matthew J. , Alvandi Bejan A. , Terry Michael A. , Tjong Vehniah K.
Published: December 2020

Introduction:

No accepted standard exists regarding the number of opioids to prescribe after many surgical procedures, and previous literature has indicated that the number of opioids prescribed influences the total number of pills consumed. The goal of this study was to investigate whether prescribing less opioids after hip arthroscopy results in less total postoperative utilization without compromising analgesia and identify risk factors for increased use.

Methods:

This study randomized 111 patients to receive either 30 or 60 tablets of hydrocodone/acetaminophen 10 to 325 mg after hip arthroscopy. Demographic information, pain instruments, and scores including International Hip Outcome Tool (iHOT-12) were collected preoperatively. Postoperatively, patients were contacted over the course of 3 weeks to determine their Numeric Pain Rating Scale scores, total number of tablets taken/leftover, and the last day that they required narcotic pain medications, which were calculated and compared for each group. Preoperative variables that increased the risk of higher narcotic pain medication requirements were assessed.

Results:

Patients in the 60-tablet group had significantly more tablets leftover than the 30-tablet group (49.5 versus 22.0, P < 0.001) and had no significant difference in Numeric Pain Rating Scale scores at 24 hours, 48 hours, or final follow-up. The 30- and 60-tablet groups demonstrated no significant difference in average tablets consumed (9.2 and 10.5, P = 0.60), respectively. Risk factors for increased postoperative opioid use included preoperative opioid use (B = 12.62, 95% confidence interval [CI], 6.28–18.96, P < 0.001) or muscle relaxant use (B = 22.45, 95% CI, 7.59–37.31, P < 0.0036) within 1 year preoperatively. Preoperative iHOT-12 scoring also significantly predicted postoperative opioid consumption in this cohort (B = −0.25, 95% CI, −0.45 to −0.036, P < 0.022).

Conclusion:

The number of leftover tablets after hip arthroscopy can be significantly reduced by prescribing 30 tablets compared with 60 tablets without affecting postoperative pain control. Total tablets prescribed in this cohort did not affect total opioid utilization. Preoperative factors including opioid or muscle relaxant use and iHOT-12 scores can be used to predict postoperative opioid requirements.
Relationship between Pre-Cystoscopy Anxiety and Post-Cystoscopy Pain: A Cross Sectional Study
Authors: Amini Abolfazl , Esmaieli Seyed Naser Seyed , Bayat Ramin , Hosseinkhani Mohammad , Ghaempanah Ali
Published: December 2020

Introduction: Cystoscopy is one of the common procedure in diagnosis and treatment of problem related to urinary tract, pre-cystoscopy anxiety is a very common problem, despite evidences shows suitable intervention for post-cystoscopy pain but enough pain relief still remains as a problem, the aim of this study was to investigate the relationship between pre-cystoscopy anxiety and post-cystoscopy pain among patients who was hospitalized for cystoscopy.

Methods: This was a cross sectional study and sampling of this study was done in April 2017 to April 2018 in surgical unit of amiralmoemenin hospital in zanjan, Iran, using non-probability convenience Sampling method, 61 patients aged 16-45 years old who was hospitalized for cystoscopy was recruited in this study. Pre-cystoscopy anxiety was assessed by spilberger (STAI) questionnaire and post-cystoscopy pain measured by pain visual analogs scale (VAS).

Results: The mean (SD) age of men and females were 43.81 (14.68), 44.88 (13.61) years old, respectively The relationship between state anxiety and post cystoscopy pain was direct and significant (p<0.05). The relationship between trait anxiety and post cystoscopy pain was direct and significant too (p<0.05).

Conclusion: the state and trait Anxiety of patients who were hospitalized for cystoscopy could increases the intensity of patients' pain in post-cystoscopy.
The scientific review – a Distinct Genre. A Descriptive Attempt with References to the Book Review
Authors: Folta-Rusin Anna
Published: December 2020

The article tries describes the characteristic features of the scientifi c review on the example of reviews of critical literary studies published in 2002–2019. The research perspective takes into account typical and variable properties of the review. The typical features: the composition corre-sponding with the composition of the work under discussion, the scientifi c style and the methods of evaluation, have been compared with selected cases where the unusual features of the meta-scientifi c text have been employed. The article takes into account the following atypical features: the violation of the stylistic convention of scientifi c discourse, the insertion of unusual components into a typical composition, the exposition of the reviewer’s research perspective on the subject. The article also identifi es the dominant models of scientifi c criticism in contemporary literary studies.
Current Situation of Nutrition Services in Selected Drug Treatment and Rehabilitation Centers in the Philippines
Authors: Angeles-Agdeppa Imelda , Santos Arias Frances Pola , Pabustan Garingo Ren Annaliz , Pascual Sy James Andrei Justin
Published: December 2020

Background: People who used drugs (PWUDs) use excessive alcohol and illicit drugs that pose a serious threat to families, society, and the nation’s health and socioeconomic status. They are also vulnerable to vitamin and mineral deficiencies that may threaten their physical and mental health and weaken their immune system. Nutrition plays an important role in the rehabilitation of PWUDs; hence, it must be integrated into the recovery programs in treatment and rehabilitation centers (TRCs). Objectives: This study was done to assess and benchmark the nutrition care processes offered to PWUDs in selected government-owned and private TRCs in the Philippines. Patients and Methods: This cross-sectional study was conducted in 19 TRCs coming from both government (n = 9) and private (n = 10) rehabilitation centers as samples from Regions I, III, IV-A, VI, XI, and National Capital Region. A total of 45 key personnel from the selected TRCs were interviewed. The information gathered by interview of the director and other key personnel on the nutrition care processes and programs offered in the center, ocular observation on dietary facilities, as well as document reviews of existing hospital policies and services. Results: Nutrition services, such as anthropometric measurements (weight and height) were only conducted in 17 TRCs, while dietary assessment (plate waste) was done only in four TRCs. None of the TRCs were able to provide nutrition counseling or education for the PWUDs. Most TRCs (57.9%) did not have their own Registered Nutritionist Dietitians (RND), and the majority (78.9%) provided uncalculated diet to PWUDs. The mean cost of meals per day was higher in the private TRCs (USD 0.96) than the government TRCs (USD 0.8). In terms of facilities, most of the TRCs had no dietary rooms (68.4%), and some of the government TRCs had no appropriate dining areas (33.3%). Conclusions: TRCs do not follow the nutritional care process in the management of PWUDs, even in some TRCs with RNDs, because they lack the environment and infrastructure to do this. These services are vital for the holistic management of PWUDs for improved quality of life. A viable recommendation is to develop a Nutrition Management Guidelines to be integrated into the manual of operations of the department of health for TRCs.
Cooperativismo de segundo grado y adopción de las TIC
Authors: Mozas Moral Adoración , Bernal Jurado Enrique , Fernández Uclés Domingo , Medina Viruel Miguel Jesús , Puentes Poyatos Raquel
Published: December 2020

El presente trabajo de investigación se centra en el estudio de los factores determinantes para la adopción de las herramientas de Tecnologías de la Información y Comunicación con objetivos comerciales en las cooperativas oleícolas de segundo grado en España. El sector oleícola español lidera la producción mundial de aceite de oliva, sin embargo, cuenta con importantes problemas comerciales que ponen en riesgo la rentabilidad de los productores. Éste es un problema históricamente ligado a este sector. En este sentido el cooperativismo de segundo grado salva una de las trabas para su avance comercial frecuentemente señalada por la literatura sobre el sector oleícola, como es la falta de concentración e integración de la oferta. Con el fin de alcanzar el objetivo establecido en este trabajo de investigación se ha hecho uso de la técnica metodológica fuzzy set Qualitative Comparative Analysis (fsQCA). Los resultados extraídos señalan que el grado de innovación tecnológica se ve favorecido por la intensidad de integración cooperativa, la formación en TIC de los empleados, la importancia comercial del sector exterior, la oferta de productos ecológicos dentro de la gama de productos de la cooperativa y el grado de compromiso de la cooperativa respecto a las acciones de Responsabilidad Social Corporativa (RSC).
Un nuevo contrato social postpandémico. El papel de la Economía social
Authors: Costas Antón
Published: December 2020

¿Qué es lo que hace que una sociedad plural funcione armoniosamente, que la economía sea inclusiva y que la democracia no caiga en el caos político? En este artículo sostendré que ese pegamento es el contrato social. Cuando ese pegamento existe, progreso económico, social y político avanzan de la mano. Sucedió así en los llamados “Treinta Gloriosos”, las tres décadas que siguieron a la Gran Depresión de los Treinta y la Segunda Guerra mundial. Sin embargo, a partir de los años ochenta del siglo pasado ese pegamento se fue disolviendo y, en paralelo, el crecimiento económico dejó de ser sinónimo de progreso social y la democracia entró en barrena. El reto ahora es reconstruir ese pegamento, al modo como se logró tras las grandes guerras. En mi opinión, ese pegamento, en primer lugar, ha de venir de un nuevo contrato social postpandémico. En segundo lugar, el núcleo de ese nuevo contrato social está en la reforma de la empresa para corregir la mala distribución del excedente (valor añadido) entre salarios, sueldos de altos directivos y dividendos. Un nuevo contrato social progresista tiene que apoyarse en la recuperación del papel fundamental del tercer pilar de la prosperidad: la Economía social.
Pirolo[1,4]benzodiazepīnu klases dabasvielu totālā sintēze / Total Synthesis of Pyrrolo[1,4] benzodiazepine Natural Products
Authors:   , Sakaine Guna
Published: December 2020

Promocijas darbā veikta sintēzes metožu izstrāde pirolo[1,4]benzodiazepīnu klases dabasvielu un to atvasinājumu iegūšanai, īpašu uzmanību pievēršot eksocikliskās dubultsaites selektīvai ievadīšanai PBD sistēmā. Development of novel synthetic methodologies toward pyrrolo[1,4]benzodiazepine class natural products and their synthetic conterparts. The main focus of Thesis is a development of efficient methods for a stereoselective introduction of exocyclic double bonds.
Massively multiplex single-molecule oligonucleosome footprinting
Authors: Abdulhay Nour J , McNally Colin P , Hsieh Laura J , Kasinathan Sivakanthan , Keith Aidan , Estes Laurel S , Karimzadeh Mehran , Underwood Jason G , Goodarzi Hani , Narlikar Geeta J , Ramani Vijay
Published: December 2020

Our understanding of the beads-on-a-string arrangement of nucleosomes has been built largely on high-resolution sequence-agnostic imaging methods and sequence-resolved bulk biochemical techniques. To bridge the divide between these approaches, we present the single-molecule adenine methylated oligonucleosome sequencing assay (SAMOSA). SAMOSA is a high-throughput single-molecule sequencing method that combines adenine methyltransferase footprinting and single-molecule real-time DNA sequencing to natively and nondestructively measure nucleosome positions on individual chromatin fibres. SAMOSA data allows unbiased classification of single-molecular 'states' of nucleosome occupancy on individual chromatin fibres. We leverage this to estimate nucleosome regularity and spacing on single chromatin fibres genome-wide, at predicted transcription factor binding motifs, and across human epigenomic domains. Our analyses suggest that chromatin is comprised of both regular and irregular single-molecular oligonucleosome patterns that differ subtly in their relative abundance across epigenomic domains. This irregularity is particularly striking in constitutive heterochromatin, which has typically been viewed as a conformationally static entity. Our proof-of-concept study provides a powerful new methodology for studying nucleosome organization at a previously intractable resolution and offers up new avenues for modeling and visualizing higher order chromatin structure.
Representación Bimodal de Valores Cardinales en la Comprensión de los Primeros Números
Authors: Rodríguez Jimena , Salsa Analía
Published: December 2020

En 2 estudios se indagó si y cómo la presentación bimodal de información cuantitativa impacta en la comprensión y el uso de los valores cardinales 1 a 6 por parte de niños preescolares. Se utilizó un diseño transversal correlacional-causal, conformándose una muestra por conveniencia de 108 niños de 3 y 4 años de cuatro jardines de infantes privados de la zona céntrica de la ciudad de Rosario, Argentina. Los niños de ambos grupos etarios resolvieron la tarea Dame un Número, en el Estudio 1 con palabras número y en el Estudio 2 con colecciones de objetos y en imágenes (condición unimodal iterativa) y con objetos e imágenes junto con sus correspondientes palabras número (condición bimodal). A través de pruebas estadísticas no paramétricas (prueba Kruskal-Wallis, prueba U de Mann-Whitney, prueba Chi Cuadrado, prueba de rangos de Wilcoxon), los resultados mostraron que los modos bimodales, en comparación con los unimodales, ampliaron de 2 a 4 el tamaño de las colecciones que los niños de 3 años fueron capaces de construir y de 3 a 6 a los 4 años. La modalidad semiótica es un factor clave al presentar y expresar información cuantitativa cuando los niños preescolares resuelven problemas que involucran números.
Una Exploración de las Propiedades Espaciales Desde la Lógica de los Programas de Estímulo
Authors: Patrón Espinosa Felipe de Jesús , González Becerra Víctor Hugo , Ortega González Mauricio , Torres Ceja Carlos de Jesús , Flores Aguirre Carlos Javier
Published: December 2020

El objetivo de este trabajo fue explorar el efecto de variar la distancia espacial entre el bebedero y el conjunto luz-palanca sobre la ubicación espacial y la tasa de respuesta en ratas. Siguiendo la lógica de los programas temporales, se diseñó un experimento en el que una propiedad espacial (distancia) de los estímulos fue manipulada, mientras que las propiedades temporales se mantuvieron relativamente estables. El Grupo 1 fue expuesto a 3 fases en las que la distancia entre el bebedero y el conjunto luz-palanca fue aumentando. El Grupo 2 fue expuesto a condiciones similares, pero la distancia espacial fue disminuyendo. Al finalizar cada ciclo T de 30 s se entregó agua de forma contingente con una probabilidad de 1. Los sujetos fueron 8 ratas hembra de la cepa Wistar. Se emplearon cámaras de condicionamiento ampliadas en las que la ubicación espacial de los dispositivos de estimulación pudo cambiar. Los resultados mostraron que las ratas permanecieron más tiempo en la zona contigua al bebedero a pesar de que este cambiara de ubicación. También, se encontró que la tasa de respuesta mostró niveles bajos para todas las ratas a lo largo del experimento, no obstante, esta fue una función de la contigüidad espacial. Las pruebas no paramétricas de Wilcoxon y de U de Mann-Whitney fueron empleadas en el análisis estadístico. Se propone una serie de propiedades espaciales como la ubicación cardinal o la distribución geográfica que podrían ser estudiadas paramétricamente e integrarse en los programas de estímulo.
DANÇA E INCLUSÃO: O PONTO DE VISTA DE ESTUDANTES DE GRADUAÇÃO
Authors: Sério Andréa , Rossi Gaya Lengler
Published: December 2020

RESUMO Este artigo apresenta a percepção de estudantes de um curso de graduação em dança sobre a sua formação acadêmica para a inclusão de pessoas com deficiência na prática da dança. Foi realizado um estudo de caso de natureza qualitativa com uso de entrevista semiestruturada como instrumento de coleta de dados. Os dados foram discutidos em interface com o conceito de aprendizagem inventiva proposto por Virgínia Kastrup, com ênfase na contextualização de relações teórico-práticas para o processo de inclusão de diferentes corpos na dança. Os resultados indicam que a inclusão de pessoas com deficiência na dança é percebida pelos participantes como uma desestabilização que potencializa o processo de ensino-aprendizagem na arte da dança.
SISTEMA PENITENCIÁRIO FEDERAL E GARANTIA DO DIREITO À EDUCAÇÃO: APROXIMAÇÕES TEÓRICAS
Authors: Barcelos Clayton Da Silva
Published: December 2020

O Sistema Penitenciário e o direito à educação escolar aos privados de liberdade são temas que vem ganhando debate no país, e distintos são os olhares acerca destas temáticas. Visando compreender como estes assuntos têm sido discutidos, o presente trabalho realizou o Estado do Conhecimento sobre o “Sistema Penitenciário Federal (SPF) e garantia do direito à educação: dos dispositivos jurídicos às práticas educacionais”. A investigação contou com a metodologia de buscas em plataformas on-line, visando uma revisão de literatura quanto a teses, dissertações e artigos sobre o tema. Os resultados demonstram que a temática é um campo a ser ampliado pela comunidade científica, visto não ter sido encontrado nenhum trabalho com o tema proposto por este estudo, uma análise da garantia do direito à educação no SPF.
ASPECTOS DO PROCESSO DE CONSTRUÇÃO DA ATIVIDADE DE PESQUISA EDUCACIONAL NO BRASIL: ANOS DE 1950
Authors: Souza Alexandre Augusto e , Moura Aline De Carvalho
Published: December 2020

O tema do artigo é a pesquisa educacional no Brasil, tendo como objetivo identificar aspectos de construção de seu campo de atividade no decênio de 1950, considerando a configuração do modelo de pesquisa que se construiu e se consolidou no país. Trata-se de um estudo bibliográfico a partir das contribuições de Florestan Fernandes e dos argumentos que traduzem a presença de demandas do Estado e de seu projeto desenvolvimentista associado aos processos de burocratização e especialização na construção institucionalizada da atividade de pesquisa educacional. Considerando as contribuições apresentadas, se pode ratificar as formas de centralização e controle do Estado nos processos institucionais que regularam os debates, as ideias e as iniciativas voltadas à atividade de pesquisa educacional.
RELAÇÃO ENTRE ESTÉTICA, EDUCAÇÃO E DESIGN: A EDUCAÇÃO ESTÉTICA
Authors: Costa Humberto , Stoltz Tania , Silva Trajano Felipe Barrabas Xavier da
Published: December 2020

Os desafios contemporâneos apontam para a imperiosa necessidade de mudanças no âmbito do conceito de Design nos cursos superiores, já que as transformações mais contundentes numa sociedade estão relacionadas diretamente com a educação. Questiona-se acerca da possível contribuição que a Estética poderia oferecer ao processo educativo na área  do designer e ,  por este motivo, a presente pesquisa  tem por objetivo refletir  sobre  as  relações entre Estética, Design e Educação, com vistas a fomentar discussão e trazer contributos que possam respaldar a Educação Estética em cursos superiores de Design. Para a realização do estudo, utilizou-se a revisão bibliográfica como método. Os resultados apontam que existe uma necessidade de ampliar o que se entende por Estética e de aprofundar a discussão acerca do relevante papel que a Educação Estética desempenha nos cursos superiores de Design.
UMA INTERVENÇÃO PEDAGÓGICA PARA A APROPRIAÇÃO DO SISTEMA DE NUMERAÇÃO DECIMAL
Authors: Magina Sandra Maria Pinto , Castro Viviane Oliveira de , Fonseca Sônia
Published: December 2020

Este artigo discute o potencial didático de uma intervenção de ensino, apoiada por jogos materiais manipulativos e discussões coletivas, para contribuir com a construção do conceito de Sistema de Numeração Decimal, por estudantes do 3º ano do Ensino Fundamental. Tendo em mente o Pacto Nacional pela Alfabetização na  Idade Certa e a alfabetização matemática do Pacto Bahia, o respaldo teórico foi a Teoria das Situações Didáticas. O estudo contou com um grupo experimental (GE) e um de grupo controle (GC), os quais passaram por um teste antes (pré-teste) e outro depois (pós-teste) uma intervenção de ensino. Os resultados nos leva a inferir a existência de um efeito positivo da intervenção de ensino proposta.
DESAFIOS PARA OFERTA DO ENSINO A DISTÂNCIA EM UNIDADES CURRICULARES ESSENCIALMENTE PRÁTICAS: O CASO DE TOPOGRAFIA I DO CURSO TÉCNICO EM AGRIMENSURA DO IFSC, CAMPUS FLORIANÓPOLIS
Authors: Cucco Dalri Julia , Von Dentz Volmir
Published: December 2020

O ensino a distância tem ganhado maior destaque nos últimos anos. Frente às inúmeras vantagens, limitações ainda configuram desafios, principalmente nos conteúdos práticos, comuns nos cursos profissionalizantes. A pesquisa identificou desafios caso fosse ofertado ensino a distância no Curso Técnico de Agrimensura do IFSC, considerando os conteúdos da unidade curricular com maior carga horária do curso, Topografia I. O estudo apresenta a legislação e revisa literaturas que abordam o ensino a distância de conhecimentos essencialmente práticos. Metodologicamente se define pela análise aplicada ao caso selecionado.  Verificou-se que alguns temas que compõem os conteúdos apontam para a possibilidade de oferta exitosa, em relação a outros, considerando suas especificidades, identificou-se prováveis ineficiências ao ensino e à aprendizagem.
Effects of injured and dead cells of Escherichia coli on the colony‐forming rate of live cells
Authors: Saito Mikako , Takatani Norimasa , Yoshida Tomonori , Mariogani Alvin , Cho Eol , Matsuoka Hideaki
Published: December 2020

Osmotic stress‐induced injured cells of Escherichia coli were prepared by sorting live cells onto tryptic soy agar (TSA) containing 10–50% sucrose. The time course of colony‐forming rate (CFR%) was analyzed. A time delay in colony formation indicated a sublethal effect. The final CFR level at 24 h indicated the relative number of culturable cells irrespective of injury. A value of (100‐CFR)% at 24 h indicated a lethal effect. When cells were grown on TSA containing 10% sucrose, the time delay was 4 h and the lethal effect was 4%. However, dead cells inhibited the growth of live cells. Physical contact with insoluble matter derived from dead cells or dead cells themselves might have caused growth inhibition. These findings highlight a novel perspective on colony count methods in practical situations, such as when sampling foods containing a high concentration of sucrose.
Trait impulsivity in Juvenile Myoclonic Epilepsy
Authors: Shakeshaft Amy , Panjwani Naim , McDowall Robert , Crudgington Holly , Peña Ceballos Javier , Andrade Danielle M. , Beier Christoph P. , Fong Choong Yi , Gesche Joanna , Greenberg David A. , Hamandi Khalid , Koht Jeanette , Lim Kheng Seang , Orsini Alessandro , Rees Mark I. , Rubboli Guido , Selmer Kaja K. , Smith Anna B. , Striano Pasquale , Syvertsen Marte , Talvik Inga , Thomas Rhys H. , Zarubova Jana , Richardson Mark P. , Strug Lisa J. , Pal Deb K. ,   the BIOJUME Consortium
Published: December 2020

Objective

Impulsivity is a multidimensional construct that can predispose to psychopathology. Meta‐analysis demonstrates an association between response impulsivity and Juvenile Myoclonic Epilepsy (JME), a common genetic generalized epilepsy. Here, we test the hypotheses that trait impulsivity is (i) elevated in JME compared to controls; (ii) moderated by specific seizure characteristics; and (iii) associated with psychiatric adverse effects of antiepileptic drugs (AEDs).

Methods

322 participants with JME and 126 age and gender‐matched controls completed the Barratt’s Impulsiveness Scale (BIS‐brief) alongside information on seizure history and AED use. We compared group BIS‐brief scores and assessed associations of JME BIS‐brief scores with seizure characteristics and AED adverse effects.

Results

The mean BIS‐brief score in JME was 18.1 ± 4.4 compared with 16.2 ± 4.1 in controls (P = 0.0007). Elevated impulsivity was associated with male gender (P = 0.027), frequent absence seizures (P = 0.0004) and lack of morning predominance of myoclonus (P = 0.008). High impulsivity significantly increased the odds of a psychiatric adverse event on levetiracetam (P = 0.036), but not any other psychiatric or somatic adverse effects.

Interpretation

Trait impulsivity is elevated in JME and comparable to scores in personality and neurotic disorders. Increased seizure frequency and absence of circadian seizure pattern moderate BIS score, suggesting disruption of both cortico‐striatal and thalamocortical networks as a shared mechanism between seizures and impulsivity in JME. These findings warrant consideration of impulsivity as a distinct target of intervention, and as a stratifying factor for AED treatment in JME, and perhaps other types of epilepsy. The role of impulsivity in treatment adherence and psychosocial outcome requires further investigation.
Surrogate Model via Artificial Intelligence Method for Accelerating Screening Materials and Performance Prediction
Authors: Wang Tian , Shao Mingqi , Guo Rong , Tao Fei , Zhang Gang , Snoussi Hichem , Tang Xingling
Published: December 2020

Predicting the performance of mechanical properties is an important and current issue in the field of engineering and materials science, but traditional experiments and modeling calculations often consume large amounts of time and resources. Therefore, it is imperative to use appropriate methods to accelerate the process of material selection and design. The artificial intelligence method, particularly deep learning models, has been verified as an effective and efficient method for handling computer vision and neural language problems. In this paper, a deep learning surrogate model (DLS) is proposed for predicting the mechanical performance of materials, that is, the maximum stress value under complex working conditions. The DLS can reproduce the finite element analysis model results with 98.79% accuracy. The results show that deep learning has great potential. This research also provides a new approach for material screening in practical engineering.
Degenerately Doped Semi‐Crystalline Polymers for High Performance Thermoelectrics
Authors: Lee Yeran , Park Juhyung , Son Jaehoon , Woo Han Young , Kwak Jeonghun
Published: December 2020

Thermoelectric (TE) energy conversion in conjugated polymers is considered a promising approach for low‐energy harvesting and self‐powered temperature sensing. To enhance the TE performance, it is necessary to understand the relationship between the Seebeck coefficient (α) and electrical conductivity (σ). Typical doped polymers exhibit α–σ relationship that is distinct from that of inorganic materials due to their large structural and energetic disorder, which prevents them from achieving the maximum TE power factor (PF = α2σ). Here, an ideal α–σ relationship in the Kang–Snyder model following a transport parameter s = 1 is demonstrated with two degenerately doped semi‐crystalline polymers, poly[(4,4′‐(bis(hexyldecylsulfanyl)methylene)cyclopenta[2,1‐b:3,4‐b′]dithiophene)‐alt‐(benzo[c][1,2,5]thiadiazole)] (PCPDTSBT) and poly[(2,5‐bis(2‐hexyldecyloxy)phenylene)‐alt‐(5,6‐difluoro‐4,7‐di(thiophen‐2‐yl)benzo[c][1,2,5]thiadiazole)] (PPDT2FBT) using a sequential doping method. The results allow the realization of the PFs reaching theoretic maxima (i.e., 112.01 µW m−1 K−2 for PPDT2FBT and 49.80 µW m−1 K−2 for PCPDTSBT) and close to metallic behavior in heavily doped films. Additionally, it is shown that the PF maxima appear when the doping state switches from non‐degenerate to degenerate. Strategies towards an optimal α–σ relationship enable optimization of the PF and provide an understanding of the charge transport of doped polymers.
Nanocellulose: Recent Fundamental Advances and Emerging Biological and Biomimicking Applications
Authors: Heise Katja , Kontturi Eero , Allahverdiyeva Yagut , Tammelin Tekla , Linder Markus B. , Nonappa  , Ikkala Olli
Published: December 2020

In the effort toward sustainable advanced functional materials, nanocelluloses have attracted extensive recent attention. Nanocelluloses range from rod‐like highly crystalline cellulose nanocrystals to longer and more entangled cellulose nanofibers, earlier denoted also as microfibrillated celluloses and bacterial cellulose. In recent years, they have spurred research toward a wide range of applications, ranging from nanocomposites, viscosity modifiers, films, barrier layers, fibers, structural color, gels, aerogels and foams, and energy applications, until filtering membranes, to name a few. Still, nanocelluloses continue to show surprisingly high challenges to master their interactions and tailorability to allow well‐controlled assemblies for functional materials. Rather than trying to review the already extensive nanocellulose literature at large, here selected aspects of the recent progress are the focus. Water interactions, which are central for processing for the functional properties, are discussed first. Then advanced hybrid gels toward (multi)stimuli responses, shape‐memory materials, self‐healing, adhesion and gluing, biological scaffolding, and forensic applications are discussed. Finally, composite fibers are discussed, as well as nanocellulose as a strategy for improvement of photosynthesis‐based chemicals production. In summary, selected perspectives toward new directions for sustainable high‐tech functional materials science based on nanocelluloses are described.
Recent Advances in Hyperthermia Therapy‐Based Synergistic Immunotherapy
Authors: Chang Mengyu , Hou Zhiyao , Wang Man , Li Chunxia , Lin Jun
Published: December 2020

The past decades have witnessed hyperthermia therapy (HTT) as an emerging strategy against malignant tumors. Nanomaterial‐based photothermal therapy (PTT) and magnetic hyperthermia (MHT), as highly effective and noninvasive treatment models, offer advantages over other strategies in the treatment of different types of tumors. However, both PTT and MHT cannot completely cure cancer due to recurrence and distal metastasis. In recent years, cancer immunotherapy has attracted widespread attention owing to its capability to activate the body's own natural defense to identify, attack, and eradicate cancer cells. Significant efforts have been devoted to studying the activated immune responses caused by hyperthermia‐ablated tumors. In this article, the synergistic mechanism of HTT in immunotherapy, including immunogenic cell death and reversal of the immunosuppressive tumor microenvironment is discussed. The reports of the combination of HTT or HTT‐based multimodal therapy with immunotherapy, including immunoadjuvant exploitation, immune checkpoint blockade therapy, and adoptive cellular immunotherapy are summarized. As highlighted, these strategies could achieve synergistically enhanced therapeutic outcomes against both primary tumors and metastatic lesions, prevent cancer recurrence, and prolong the survival period. Finally, current challenges and prospective developments in HTT‐synergized immunotherapy are also reviewed.
Real‐time optimization for nonlinear processes including output saturation
Authors: Ahn Gwang‐Noh , Lim Sanghun , Sung Su Whan , Lee Jietae
Published: December 2020

Output saturation is observed in many chemical processes and microbial cultivation processes. In these processes, output saturation can cause a number of control problems near the saturation point due to the nonlinear continuous input multiplicity interval after the saturation point. In general, the widely used proportional‐integral‐derivative (PID) controller cannot perform its function due to the nonlinearity. In particular, the accumulated error due to the integration term in the saturation region may result in a reduction in the energy efficiency and in an overloading of the process. Two solutions to this optimization problem are presented in this study. The first is to eliminate input multiplicity through a modified PID controller that introduces a new output value with the input signal added. The second is to find the optimal point of the nonlinear saturation process using extremum seeking control with continuous perturbation. Overflow experiments and simulations involving the liquid level system were performed for both solutions. Both methods have different characteristics, but both exhibit remarkable performance and stability improvements over conventional control systems.
Free serum sorbitol and its interaction with caffeine: A suggestive approach for plausible remediation of diabetic neuropathy
Authors: Srivastava Bhavya , Sen Souvik , Sen Kamalika
Published: December 2020

The measure of sorbitol in serum can act as a good indicator in the monitoring of the diabetic complications. To analyze the sorbitol level in serum medium, fluorometric enzymatic assay was performed. To remove the excess sorbitol from the body, proposed binding of sorbitol with caffeine was investigated. Their interaction in serum medium was studied and established by UV‐Vis, fluorescence spectrophotometry, and time‐correlated single photon counting (TCSPC). The linear calibration of sorbitol (in the range 10–50 mM) was done using UV‐Vis spectrophotometry. Time scan experiments furnished the reaction rate of sorbitol assayed solution as well as sorbitol–caffeine complex as 0.021 min−1 and 0.018 min−1, respectively. A sudden drop was observed in the fluorescence lifetime of reduced nicotinamide adenine dinucleotide (NADH) present in sorbitol assayed solution upon complexation with caffeine, that is, from 1.774 × 10−09 to 1.23 × 10−10 Sec, which indicates the hindrance in the formation of NADH and the probable formation of some other species. Isothermal titration calorimetric experiments clearly indicate the number of binding sites (i.e., 3.89, 1.40, and 2.07) that exist between sorbitol and caffeine at the complexation ratio of 1:1.2, 1:1.5, and 1:3. The present method can be helpful in pharmacological and therapeutic studies of sorbitol using caffeine for treating diabetic neuropathy.
The Unflinching Mr. Smith and the Nuclear Age**
Authors: Turchetti Simone
Published: December 2020

This article focuses on the U.S. diplomat and nuclear arms control negotiator Gerald (Gerry) Coat Smith in order to cast new light on the importance of diplomats in the context of the set of international activities currently labelled as “science diplomacy.” Smith, a lawyer by training, was a key negotiator in many international agreements on post‐WW2 atomic energy projects, from those on uranium prospecting and mining, to reactors technologies to later ones on non‐proliferation and disarmament. His career in science (nuclear) diplomacy also epitomized the shortcomings of efforts to align other countries’ posture on nuclear affairs to U.S. wishes. In particular, the unswerving diplomat increasingly understood that strong‐arm tactics to dissuade other countries from acquiring nuclear weapons would not limit proliferation. Not only did this inform later U.S. diplomacy approaches, but it lent itself to the ascendancy of the new notion of “soft power” as critical to the re‐definition of international affairs.
Purification and Identification of Pine Nut (Pinus yunnanensis Franch.) Protein Hydrolysate and Its Antioxidant Activity in Vitro and in Vivo
Authors: Liu Zitian , Shi Yuming , Liu Huiping , Jia Qi , Liu Qingrun , Tu Jianqiu
Published: December 2020

In this study, the pine nut (Pinus yunnanensis Franch.) protein was hydrolyzed by alkaline protease and trypsin to prepare pine nut protein hydrolysate (PNPH). The chemical, intracellular and in vivo antioxidant capacity of PNPH were evaluated. PNPH owned the ability of scavenging free radicals, and it could protect the HepG2 cells from oxidative damage by preserving cell viability. Moreover, PNPH could reduce the malondialdehyde (MDA) content and improved the superoxide dismutase (SOD) and glutathione peroxidase (GSH‐Px) activities in serum, heart and liver of aging mice induced by D‐galactose. Further, the PNPH was stepwise purified and identified, and 15 peptides were identified from purified fraction in PNPH. The three‐dimension structures of identified peptides were predicted. Among all identified peptides, peptide 3, 7, 8 and 11 were presumed to possess good antioxidant activity. Overall, PNPH and purified peptides isolated from PNPH have potential application prospects in the field of natural antioxidants and anti‐aging functional foods.
Impact of intracoronary imaging on in‐hospital mortality and 30‐day readmission rates following percutaneous coronary intervention: A nationwide readmissions database analysis
Authors: Lazkani Mohamad , Tripathi Byomesh , Dattilo Philip
Published: December 2020

Background

Percutaneous coronary intervention (PCI) is well established for the treatment of obstructive coronary artery disease. This study was performed to assess the impact of in‐hospital mortality and 30‐day readmission with intracoronary imaging as an adjunct to baseline coronary angiography.

Methods

The study was derived from the Healthcare Cost and Utilization Project's National Readmission Database (NRD) of 2016, sponsored by the Agency for Healthcare Research and Quality. Patients who underwent PCI were identified using appropriate ICD‐10 codes. Study population was further subcategorized into 2 PCI arms: intravascular imaging (''imaging'' group) and fluoroscopy guided (''angiography'' group). Primary endpoints were 30‐day readmissions and in‐hospital mortality. Secondary endpoints were length of stay, cost of care, predictors of 30‐day readmission and in‐hospital mortality in PCI related hospitalizations.

Results

We identified in total 188,368 index admissions, with 12,379 patients in the “imaging‐guided” group and 175,989 in the “angiography‐alone” group. There were no differences in 30‐day readmissions between both groups (~10.8% in both arms, p = .788). However, in‐hospital mortality carried a statistically significant reduction with use of imaging‐guided PCI (1.72% vs 2.24%, p = .004). The median length of stay was longer in the imaging‐guided arm (3 vs. 2 days, p < .001), associated with larger median total hospital costs ($32,123 USD vs. $25,162 USD, p < .001). The strongest predictor of in‐hospital mortality in both univariate and multivariate analysis was having an existing coagulopathy.

Conclusion

The results of this study did not confer benefit with regards to 30‐day hospital readmission rates when utilizing intracoronary imaging versus angiography‐alone in percutaneous coronary intervention, but did suggest there may be an association between the use of intracoronary imaging and improved in‐hospital mortality. In addition, resource utilization was higher in the intra‐coronary imaging arm of the study.
Pituitary hyperplasia due to Himalayan endemic hypothyroidism
Authors: Sapkota Shabal , Sapkota Sulav , Karn Mitesh
Published: December 2020

Pituitary hyperplasia due to hypothyroidism can be treated medically. This condition should not be mistaken for adenoma and surgery should be avoided.
Transient aphasia following general anesthesia in patient undergoing laparoscopic gynecologic surgery: A case report and literature review
Authors: Zhang Junbao , Yang Manping , Dong Hailong , Lu Zhihong
Published: December 2020

Aphasia could be a manifestation of postoperative psychoemotional disorder. Early differential diagnosis is important.
Na0.67Mn(1‐x)FexO2 Compounds as High‐Capacity Cathode Materials for Rechargeable Sodium‐Ion Batteries
Authors: Siriwardena Dumindu P. , Fernando Joseph F. S. , Wang Tony , Firestein Konstantin L. , Zhang Chao , Lewis Courtney‐Elyce , von Treifeldt Joel E. , Golberg Dmitri V.
Published: December 2020

Herein, we report on electrochemical and structural properties of low‐cost Na0.67Mn(1‐x)FexO2 (NMFx) cathode materials synthesized through substitution of Mn with small amounts of Fe. The materials were fabricated using a simple solid‐state synthesis method. Electrochemical performance of the cathodes was significantly improved when initial electrochemical activation had been performed. Activated Na0.67Mn0.9Fe0.1O2 material displayed a high capacity of 132 mAh/g after 100 cycles and delivered an exceptionally high rate capability of 116 mAh/g at 500 mA/g. Energy‐dispersive X‐ray spectroscopy (EDX), cyclic voltammetry (CV) and ex situ X‐ray photoelectron‐spectroscopy (XPS) analyses suggested that Fe had played a structural as well as an electrochemical role in cathode performance. Ex situ and in situ X‐ray diffraction (XRD) studies were used to analyze the associated structural variations during the capacity evolution.
Intracellular Logic Computation with Framework Nucleic Acid‐Based Circuits for mRNA Imaging†
Authors: Song Ling , Xiao Mingshu , Lai Wei , Li Li , Wan Ying , Pei Hao
Published: December 2020

Main observation and conclusion

DNA circuits have been designed for implementation of various functions based on DNA strand displacement in cell‐free settings, but their capabilities in biological environments remain limited. In this work, we report framework nucleic acid (FNA)‐based circuits enabling intracellular logic computation for mRNA imaging. FNAs as rigid scaffolds enable to deliver our built DNA circuits into cells without aid of transfection reagents, evading a time‐consuming and tedious process prior to analysis, and the pendant duplex DNA designed at one vertex of FNA as gate is suitable for four‐way strand exchange, minimizing crosstalk with other nucleic acids in the cellular milieu. We demonstrated that such FNA‐based circuits can operate both in vitro and in vivo logic computation, including OR and AND logic gates. Moreover, in situ mRNA imaging was also realized by exploiting native mRNA as scaffolds to bind multiple FNA‐based gates for the enhanced signal‐to‐background ratio. We hope that this FNA‐based circuit can be applied for disease diagnosis, facilitating the development of biomedicine.