bluuebunny/crossref_metadata_2025 huggingface dataset:
Between Women: Narratives of Estonian Lesbians and a Bisexual During the Transition from Soviet Times
Authors:   Estonian Academy of Music and Theatre, Davidjants Brigitta
Published: March 2024

In this article, I analyse the life narratives of three Estonian women who identify as either lesbian or bisexual. Based on three semi-structured in-depth interviews, I focus on the period when the local LGBTQ+ movement became active, during the 1980s and 1990s, after half a century of Soviet dominance that had crumbled and Estonia regained independence. The process of growing older, combined with the individual’s biography, along with added depths of memory and critical reflection, are key elements in interpreting the social significance of their personal experiences. By using thematic analysis, I reveal how these personal experiences can become a shared narrative while letting us focus on the uniqueness of each life history.
The Elements of Sea Power and the Indo-Pacific Strategy of the West Asian Region
Authors: Zafar Javed
Published: March 2024

During the last three decades, China has made significant progress, especially in the fields of economic development, defence, science and technology, and multilateral cooperation. Its emergence as a global power has also increasingly been challenging the US position. Many economic and strategic initiatives taken by China have provided it with strategic space and depth in the neighbouring region as well as the world also. The country is now openly displaying its military power and acting as a hegemon in the South and the East China Sea. The US is trying to counter the emerging influence of China by developing different alliances and partnerships in the Asia-Pacific and other regions. Thus, rivalry and tension have been increasing between China and the US and its allies. The present study analyses the designs of these emerging tensions and conflicts in the Indo-Pacific Region (IPR). The neighbouring West Asian Region (WAR), a playground of different global powers, is also a crucial region for the Indo-Pacific strategic game plan. The WAR has historically been dominated by the West and is therefore an integral part of their strategic thinking. Therefore, the necessity for the WAR to precisely define its strategic interest and responsibility for all surrounding regions and global powers has also been discussed. A discussion has also been made of current naval strength and how to unite it into a single unit. The geopolitical vision of Alfred Thayer Mahan in the form of the ‘Elements of Sea Powers’ has also been analysed to conclude as to how the WAR should adopt them to become a great naval power. In conclusion, the study also provides many suggestions and options for WAR’s Indo-Pacific strategy. The paper is based on secondary data. Meanwhile, the analytical descriptive approach adopted for the present research is based on the analysis of historical facts, discourse, and political developments. The data is collected from various books, journals, government portals, reports, newspapers, and publications of many institutions and organisations.
CPT1A Protects Podocytes from Lipotoxicity and Apoptosis In Vitro and Alleviates Diabetic Nephropathy In VivoThe role of CPT1A in diabetic kidney disease
Authors: Xie Yajuan , Yuan Qian , Tang Ben , Xie Yaru , Cao Yiling , Qiu Yang , Zeng Jieyu , Wang Zhiwen , Su Hua , Zhang Chun
Published: March 2024

Abstract

Defective fatty acid oxidation (FAO) has been implicated in diabetic kidney disease (DKD), yet little is known about the role of carnitine palmitoyltransferase-1A (CPT1A), a pivotal rate-limiting enzyme of FAO, in the progression of DKD. Here, we investigate whether CPT1A is a reliable therapeutic target for DKD. We first confirmed the downregulation expression of CPT1A in glomeruli from diabetic patients. We further evaluated the function of CPT1A in diabetic models. Overexpression of CPT1A exhibited protective effects in diabetic conditions, improving albuminuria and glomerular sclerosis, as well as mitigating glomerular lipid deposits and podocyte injury in streptozotocin-induced diabetic mice. Mechanistically, CPT1A not only fostered lipid consumption via fatty acid metabolism pathways, thereby reducing lipotoxicity, but also anchored Bcl2 to the mitochondrial membrane, thence preventing cytochrome C release and inhibiting the mitochondrial apoptotic process. Furthermore, a novel transcription factor of CPT1A, FOXA1, was identified. We elucidate the crucial role of CPT1A in mitigating podocyte injury and the progression of DKD, indicating that targeting CPT1A may be a promising avenue for DKD treatment.
The Process of Learning English Speaking Skills in Nursing Class
Authors: Pebriano Nor Angga , Rafidiyah Dina , Sarmila Sarmila , Murtiningsih Tenny , Fauziah Nita , Farhan Miftah Al , Wariyatun Wariyatun , Ifani Muhammad Zulfi , Pradana Fajar Gemilang
Published: March 2024

Learning English for nurses is very important because there are many English terms that nurses must know. In addition, for career needs it is also necessary that someone can speak English. Therefore, learning English for nursing is important. This research was case study in qualitative research. its assumed that this study aims to find out the way nursing students learn speaking skills. This research was conducted at a private university in South Kalimantan. In the English class of students majoring in nursing class of 2021, The findings from this study used interviews with two nursing students and one English lecturer who taught nursing classes. The results found that the process of students learning English was quite diverse. because by mastering a foreign language when they carry out their duties as medical personnel they have no difficulty communicating. It can be concluded that the way students learn speaking for the nursing profession is quite diverse, some use strategies through the habit of watching English films, some use materials from lecturers to improve their speaking skills.
Exploring Integrated Vocabulary and Speaking Learning in “Spoken English Vocabulary and Corpus” Class
Authors: Riskina Aulia , Rafidiyah Dina , Nurfauziah Dwi Hana , Dayanti Gista Rahma , Aflahah Noor Aida , Amalin Khusnul , Andreas Rino , Saputro Duwi
Published: March 2024

This article explores the strategy of integrating vocabulary and speaking learning in spoken English classes and investigates how lecturers teach these skills. The integration of vocabulary and speaking is essential as speaking is a productive skill that requires input (vocabulary) and output (spoken English). This study aims to delve into how this integration enhances speaking skills by providing language exposure through contextually relevant vocabulary usage. The lecturer's approach involves situational learning videos, focusing on pronunciation and contextual understanding. Moreover, the incorporation of corpus data, depicting vocabulary usage in various speaking contexts, aids students in practicing vocabulary in appropriate situations. The results showcase a spectrum of student responses, ranging from natural speakers to those reliant on scripted preparation. Assignments, including role-plays and conversational scenarios, foster vocabulary utilization in congruent contexts. Student interviews reflect improved understanding of spoken English through vocabulary exploration strategies, facilitating comprehension and communication. The study concludes that integrating vocabulary and speaking learning enhances spoken English proficiency, guiding educators to develop more effective teaching methodologies. Future research recommendations include expanding participant numbers for richer data insights.
Estimasi Harga Bawang Bawang Di Jawa Timur Menggunakan Model Multilayer Perceptron
Authors: Pradana Yan Aditya , Dewi Lenny Puspita , Pramudito Wysnu , Fauzi Irfan Miftahul , Negara Santosa Pradana Putra Setia , Iswari Dian Ardhifa , Mudzakkir Moh. , Handayani Trisakti
Published: March 2024

Indonesia adalah negara yang dikenal dengan beragam produk pertanian. Produk pertanian yang dihasilkan meliputi pangan dan hortikultura. Produk hortikultura yang sering ditanam oleh masyarakat adalah bawang merah. Bawang merah merupakan salah satu komoditas yang memiliki tingkat risiko yang tinggi yaitu harga yang fluktuatif. Harga bawang merah dapat naik dan turun hanya dalam waktu beberapa minggu. Fluktuasi harga bawang merah dapat terjadi karena tidak ada aturan yang melindungi harga bawang merah. Kondisi mekanisme pasar menentukan harga bawang merah, sehingga hukum penawaran dan permintaan menentukan naik turunnya harga. Langkah-langkah yang tepat diperlukan untuk memprediksi harga bawang merah dalam beberapa periode berikutnya dan meminimalkan risiko kerugian petani. Harga bawang merah berubah setiap minggu, sehingga diperlukan prediksi harga bawang merah menggunakan metode Multilayer Perceptron (MLP). Multilayer Perceptron (MLP) adalah salah satu Jaringan Saraf Tiruan (ANN) yang populer. Model MLP yang dibangun terbukti dapat memprediksi harga bawang merah di Jawa Timur. Perbandingan data uji dan pelatihan terbaik adalah 2:1, yang memiliki kesalahan terkecil dari model lainnya. Ini bisa disebabkan oleh faktor parameter yang tidak sesuai. Perbedaan jumlah epoch dalam penelitian ini berdampak signifikan dalam meminimalisasi kesalahan.
Penyelesaian Aplikasi Persamaan Diophantine dengan Algoritma Euclid
Authors: Pradana Yan Aditya , Dewi Lenny Puspita , Rahmah Maulida Atsaniatu , Wijanarko Ardi , Ishartono Naufal , Kusumaningtyas Dian Artha
Published: March 2024

Persamaan diophantine Linier memiliki dua variabel yang mana variabelnya berbentuk bilangan bulat. Solusi yang dapat diselesaikan pada persamaan diopanthine adalah solusi bilangan bulat. Untuk mengetahui apakah persamaan tersebut memiliki solusi bulat atau tidak maka diperlukan algoritma euclid untuk menyelidiki. Dengan algoritma Euclidean dicari Faktor persekutuan terbesar dari masing-masing variable yang ada pada persamaan yang mana hasil dari penghitungan FPB ini merupakan solusi terbaik dari persamaan Linier Diophantine. Berdasarkan analisis hasil dan pembahasan yang telah dibahas, permasalahan pada aplikasi persamaan Diophantine Linier dapat secara mudah dilakukan dengan menggunakan algoritma Euclid. Untuk menyelidiki apakah persamaan tersebut diophantine atau tidak dapat dilakukan dengan dengan penghitungan FPB variabel  dan  dari persamaan  yang mana.  Pada penghitungan  didapat , sehingga  memiliki solusi bulat. Persamaan diophantine Linier dapat diaplikasikan dalam materi program Linier 2 variabel yang diajarkan di tingkat SMP dan SMA, dengan algoritma Euclid persamaan Linier dengan syarat (a,b)|c dapat dipenuhi yang kemudian dapat dilanjutkan langkah pembalikan algoritma euclid untuk menemukan solusi bulat.
CHALLENGING THE INTERPRETATION OF THE VERSE ON HIJAB BY M. QURAISH SHIHAB: A CRITICAL ANALYSIS REVIEW
Authors: Rohman Abdul , Muttaqien Ghazi Abdullah , ALMonawer Faisal Hamad , Rumanian Tigran , Deik Mohammad
Published: March 2024

There is a variety of interpretations regarding the verse on the hijab in the Qur'an. Some commentaries demonstrate strong arguments, while others appear to be subjective and ambiguous. This article examines the thoughts of Quraish Shihab on the hijab verse and critically analyzes them. The research falls under the category of library research, utilizing a descriptive analysis method to explain research findings based on the study's focus with a critical analysis to produce objective results. The approach employed is content analysis. The primary sources for this research are the Tafsir Al-Mishbah and Jilbab Pakaian Wanita Muslimah. The research findings indicate: First, Quraish Shihab argues that wearing the hijab is not obligatory but merely a recommendation and is applicable only in the time of Prophet Muhammad. Scholars also do not agree on the limits of women's modesty, and the rules of the hijab are considered part of Arab cultural traditions, not applicable to other nations that do not wear the hijab. Second, Quraish Shihab's interpretation of the hijab verse lacks strong arguments in the context of Islamic studies. The wording of the command in the hijab verse is still regarded as an obligation and cannot be transformed into a recommendation due to the lack of supporting evidence. Scholars have unanimously agreed on the limits of women's modesty, from the top of the head to the tips of the toes, excluding the face and the palms of the hands. The law of the hijab remains in effect until the end of time, even though it was revealed under specific conditions and in specific regions, as Islam is considered a universal religion.
The Benefits of Digital Literacy for Psychiatric Disease through Educational Activities
Authors: Sandalis Ioannis Georgios , Taskou Eirini Efthymios , Mougiou Stavroula Konstantinos
Published: March 2024

Democracy, equality, and inclusion require equal opportunities for everyone to have access to all types of education, in specific to ICT content. This paper intends primarily to examine whether it is feasible to teach people with mental illness to use a tablet and secondarily whether the usage of ICT contributes to the enhancement of cognitive and social skills, to the improvement of psychology, quality of life and to the increase of the functionality of these people in the context of their psychosocial recovery. The method chosen for this study is “action research”, for the needs of which an educational activity was conducted, which had a participatory, collaborative and experiential character, in an untypical learning environment, such as that of the Psychiatric Hospital of Attica (Ps.H.A.) “Dromokaiteio”. The results of this research demonstrate both that it is possible for people with mental illness to become familiar with the use of ICT through educational courses and that the influence of ICT is especially effective in enhancing factors that affect the quality of life of people with mental disorder.
Determinantes de sucesso na aplicação de métodos ágeis na gestão de projetos
Authors: Zacarias Sérgio Pinto , Sbragia Roberto , Silva João
Published: March 2024

Objetivo: Analisar os fatores críticos que influenciam o sucesso do gerenciamento ágil de projetos.
Originalidade/Relevância: O resultado foi a obtenção de um modelo de pesquisa com indícios de qualidade técnica, oriundo da fusão de itens observáveis consagrados na literatura, com a lógica de seus agrupamentos determinada pela afinidade dos dados empíricos.
Metodologia: Foi realizada uma coleta de dados com questionários eletrônicos do tipo survey. Foram aplicadas técnicas de Análise Fatorial Exploratória, Confirmatória e de Modelagem de Equações Estruturais. A análise contemplou 475 projetos gerenciados com várias abordagens ágeis, desenvolvendo produtos de software, não-software e serviços, em organizações de diferentes portes, setores e atividades.
Resultados: Foi verificado que fatores inerentes às características do projeto e do ambiente organizacional são mais críticos. Os fatores “Dedicação dos Participantes”, “Experiência dos Participantes” e “Projeto e Ambiente Organizacional” estão associados positivamente ao Sucesso dos Projetos Ágeis.
Conclusão: Foi possível perceber indícios de que o fator humano é crítico para se alcançar o nível de desempenho desejado pelas organizações.
Overview of PNM Mekaar's Development in Improving Community Economic Prosperity in Pauh District, Padang City
Authors: Angriani Wiwit , Wisroni Wisroni
Published: March 2024

The background of this research is the success of members in opening and developing businesses. This study aims to: 1. See the describtion of guidance in the construction of PNM Mekaar in the Economic walfare of the community in Pauh Padang district, 2. See the description of the development in the economic walfare of the community in Pauh Padang district, 3. See the description of supervision in the guidance of PNM Mekaaar in the economic welfare of the community in Pauh Padang District. The study uses a quantitative approach, with a descriptive type. The data analysis technique uses the percentage formula. The research population was 30 study residents and a sample of 67%, namely 20 people. The sampling technique used is simple random sampling. Technique in collecting data using questionnaires and data collection tools in the form of a list of statements. The result  of the study found that: (1) The description of guidance in construction of PNM Mekaar in the economic welfare of the community in Pauh Padang distrit was categorized as good, (2) The description of development in the construction PNM Mekaar in the economic welfare of the community in Pauh Padang district is categorized as good, (3) The description of supervision in construction PNM Mekaar in the economic welfare of the community in Pauh Padang district is categorized as good. Suggestions are expected for further researchers to be able to innovate by researching new variables so that they can add and multiply exixting variables.Keywords: constructions, walfare
The Relationship between Ustadz Supervision and Student Discipline in Pondok Tahfizh Darul Qur'an Surau Polak Botuang Nagari Pangian Lintau Buo District Tanah Datar District
Authors: Veronika Nadya , Jamaris Jamaris
Published: March 2024

This research was motivated by the low discipline of the students at the Tahfizh Darul Qur'an Islamic Boarding School, Surau Polak Botuang Nagari Pangian, Lintau Buo District, Tanah Datar Regency. This is presumably due to the low level of supervision of students of Ustadz. Aims to find out of Ustadz supervision, students discipline and the relationship between the two variables. This type of research is quantitative research with a correlational approach. The population of the study were all students who were active at Pondok Tahfizh, totaling 96 students. The research sample was taken based on cluster sampling with total 76 samples. The data collection technique is questionnaire. The data analysis technique in this study uses the percentage and product moment formulas. The results showed that (1) supervision of Ustadz was still low, (2) discipline of students was still low, and (3) there is a significant relationship between supervision by Ustadz and discipline of students. Based on this research, it hoped that (1) It is suggested to the managing institution of Pondok Tahfizh Darul Qur'an Surau Polak Botuang to strengthen supervision and monitor the implementation of regulations so that they are appropriate and on target. (2) It is recommended that ustadz be more disciplined in enforcing regulations, increasing learning and supervising congregational prayers for students so that the vision and mission of Tahfizh Darul Qur'an Islamic boarding school Surau Polak Botuang is realized. (3) It is recommended that students be more disciplined in complying with the regulations that have been made by the ustadz, so that students get used to these habits from an early age so they are able to apply them both at Pondok Tahfizh Darul Qur'an or at home.Keywords:  Supervision Ustadz, Student Discipline
Description of the Relationship between Learning Activities and Learning Outcomes of Training Participants at LPK Hoshi Hikari Parupuk Tabing Padang City
Authors: Febriansyah Pradi Ciaca , 'Aini Wirdatul
Published: March 2024

This research was motivated by the low learning outcomes of the trainees atLPK Hoshi Hikari Parupuk Tabing, Padang City. This is presumably due to the lowactivity of the trainees resulting in low learning outcomes of the trainees. This studyaims to: 1) See an overview of the active learning of the training participants at LPKHoshi Hikari Parupuk Tabing, Padang City. 2) See an overview of the learningoutcomes of the training participants at LPK Hoshi Hikari Parupuk Parupuk Tabing,Padang City. 3) To determine the relationship between active learning and learningoutcomes of trainees at LPK Hoshi Hikari Parupuk Tabing, Padang City.This type of research is quantitative with this type of correlational research.The population in this study was 30 people and 21 people were taken as samples byusing stratified random sampling technique. Data collection techniques using aquestionnaire. Data analysis techniques use percentage formulas and rank orders.The results showed that: 1) the learning activity of the training participants atLPK Hoshi Hikari Parupuk Parupuk Tabing, Padang City was categorized as low; 2)The description of the learning outcomes of the training participants at LPK HoshiHikari Parupuk Tabing Padang City is categorized as low; 3) There is a significantrelationship between learning activity and the learning outcomes of the trainees atLPK Hoshi Hikari Parupuk Tabing, Padang City. Research suggestions are: 1) forinstructors to be able to innovate regarding learning activities so that it can be anattraction for training participants to be active in the learning carried out; 2) It ishoped that future researchers will be able to innovate and examine new variablesso that they can add to existing variables and complete them.
The Impact Of Learning Habits And Social Support On The Learning Climate Of Package C At PKBM Delima Bandara Padang Pariaman Regency
Authors: Trinanda Rani , Dwi Arini Fitri
Published: March 2024

ABSTRACTThe aim of this research is to investigate the impact of learning habits and social support on the learning climate of Package C learners at PKBM Delima Bandara, located in Padang Pariaman Regency. Employing a quantitative explanatory research approach, the study utilizes multiple regression analysis techniques. The population consists of all Package C students at PKBM Delima Bandara, totaling 77 individuals, with a sample size of 43 chosen through simple random sampling. The instrument is using questionnaires. The findings indicate that both learning habits and social support, both individually and collectively, have a positive and statistically significant influence on the learning climate of Package C. This suggests that improved learning habits and access to social support positively contribute to the creation of a conducive learning environment at PKBM Delima Bandara. Hence, it is recommended that learners focus on developing effective learning habits and leverage available social support networks to enhance the overall learning climate. Keywords: learning habits, social support, learning climate, package C
PHYSICAL FITNESS VALUE OF STUDENTS OF PRIVATE JUNIOR HIGH SCHOOL BHAYANGKARI 2 KABANJAHE
Authors: Barus Join Marshelindo , Ibrahim Ibrahim
Published: March 2024

This study aims to determine the level of physical fitness of students at Private Middle School Bhayangkari 2 Kabanjahe. This research was conducted at the Samura sports stadium. Data collection was carried out in October. The method used in this research is descriptive method by conducting tests and measurements. The test used was the Indonesian Physical Fitness Test for Junior High Schools, aged 13-15 years with a total sample of 40 people whose determination was based on purposive sampling. The results of this study did not find a level of physical fitness Very Good or 0.00%, nor found a level of physical fitness Good or 0.00%, in the moderate category there were 11 students or 27.50%, in the Less category there were 27 students or 67.50 %, in the Less Once category there are 2 students or 5.00%. Overall, the physical fitness level of the students of SMP PRIVATE BHAYANGKARI 2 KABANJAHE is 12.23 in the less category.
ONLINE IMPLEMENTATION OF HEALTH AND SPORTS PHYSICAL EDUCATION LEARNING IN JUNIOR HIGH SCHOOLS IN AIR WHITE SUB-DISTRICT, BATU BARA DISTRICT FOR ACADEMIC YEAR 2021/2022
Authors: Afdillah Ibnu , Damanik Suryadi
Published: March 2024

This study aims to identify and analyze the implementation of online Physical Education, Sports and Health learning in junior high schools in Air Putih District, Batu Bara Regency for the 2021/2022 academic year. This research is a quantitative descriptive research and survey method. The sample in this study was 90 students, consisting of 3 schools, namely 30 students from SMP Negeri 1 Air Putih, 30 students from SMP Negeri 3 Air Putih, and 30 students. /i and Water Al Washliyah Private Middle School 6. This study has 9 indicators that are used as a reference for assessing the level of implementation of online Physical Education Sports and Health learning. The results of this study are: (1) Indicators of learning readiness, 83.78%; (2) Learning Material Suitability Indicators, 60.07%; (3) Learning Method Indicator, 82.59%; (4) Learning Media Indicators, 58.96%; (5) Material Mastery Indicator, 70.74%; (6) Learning Process Indicator, 70.67%; (7) System Indicators and Assessment Process, 79.56%; (8) Learning Constraints Indicator, 60%; (9) Learning Evaluation Indicator, 85.70%. Of the 9 indicators, it can be concluded that the level of implementation of online Physical Education, Sports and Health learning in junior high schools in Air Putih District, Batu Bara Regency is 72.45% in the good category.
ANALISIS NILAI PERUSAHAAN PADA SEKTOR BASIC INDUSTRY AND CHEMICALS YANG TERDAFTAR DI BURSA EFEK INDONESIA
Authors: Pratama Mochammad Bagus Akbar , Takarini Nurjanti
Published: March 2024

Penelitian ini bertujuan untuk menguji apakah terdapat pengaruh profitabilitas, leverage, dan ukuran perusahaan terhadap nilai perusahaan yang terdaftar di Bursa Efek Indonesia. Perusahaan yang menjadi objek penelitian ini yaitu perusahaan sektor basic industry and chemicals yang terdaftar di Bursa Efek Indonesia periode 2016-2019. Sampel yang diambil yaitu sejumlah 47 perusahaan dengan metode pengambilan sampel berupa metode purposive sampling. Penelitian dilakukakan dengan teknik analisis linier berganda menggunakan uji asumsi klasik dengan bantuan SPSS sebagai alat pengolahan data. Hasil penelitian menyebutkan bahwa secara parsial variabel profitabilitas dan leverage mempunyai pengaruh positif dan signifikan terhadap nilai perusahaan, sedangkan ukuran perusahaan mempunyai pengaruh negatif dan tidak signifikan terhadap nilai perusahaan
Effect of Methotrexate on Anti-Mullerian Hormone Levels, β-hCG and Tumor Size in Women with Low-Risk Gestational Trophoblast Disease
Authors: Madjid Tita Husnitawati , Masitoh Imas , Harsono Ali Budi , Purwara Benny Hasan , Rinaldi Andi , Mose Johannes Cornelius , Sunardi Sunardi
Published: March 2024

Introduction: This study aimed to evaluate the effect of methotrexate (MTX) chemotherapy on anti-mullerian hormone (AMH) levels, human chorionic gonadotropin (HCG) levels, and tumor size in women with gestational trophoblastic disease (GTD). Method: This study was conducted at Hasan Sadikin General Hospital, Bandung, West Java, from April to October 2020. The AMH level, beta human chorionic gonadotropin (ß-hCG) and tumor size in women with a low risk of GTD prior to and after MTX chemotherapy treatment were measured and compared.Results: Our study found a reduction in mean AMH level to 0.82 ng/ml after the MTX chemotherapy. The mean AMH level after chemotherapy in women with low-risk GTD decreased to 0.82 ng / ml. In addition, ß-hCG level decreased after chemotherapy with MTX. There was a negative relationship between ß-hCG level and tumor size before and after chemotherapy. Higher ß-hCG levels and tumor size before chemotherapy resulted in a further increase in AMH after chemotherapy.Discussion: There was a decrease in AMH and ß-hCG levels after three cycles of MTX chemotherapy in women with low-risk GTD. Tumor size and ß-hCG correlated with post-chemotherapy AMH results.Pengaruh Metotreksat terhadap Kadar Hormon Anti Mullerian, β-hCG dan Ukuran Tumor pada Wanita dengan Penyakit Trofoblas Gestasional Risiko RendahAbstrakPendahuluan: Penelitian ini mengevaluasi efek kemoterapi metotreksat (MTX) terhadap kadar hormon anti-mullerian (AMH), kadar human chorionic gonadotropin (HCG), dan ukuran tumor pada wanita yang didiagnosis penyakit trofoblas gestasional (GTD) risiko rendah.Metode: Penelitian ini dilakukan di Rumah Sakit Umum Pusat Hasan Sadikin, Bandung, Jawa Barat, dari bulan April hingga Oktober 2020. Kadar AMH, beta human chorionic gonadotropin (ß-hCG), dan ukuran tumor pada wanita dengan GTD risiko rendah sebelum dan sesudah pengobatan kemoterapi MTX diukur dan dibandingkan.Hasil: Pada penelitian kami menemukan penurunan kadar AMH rata-rata menjadi 0,82 ng/ml setelah kemoterapi MTX. Rata-rata kadar AMH setelah kemoterapi pada wanita dengan GTD risiko rendah menurun menjadi 0,82 ng/ml. Selain itu, kadar ß-hCG juga menurun setelah kemoterapi dengan MTX. Terdapat hubungan negatif antara kadar ß-hCG dan ukuran tumor sebelum kemoterapi dan AMH setelah kemoterapi. Kadar ß-hCG yang lebih tinggi dan ukuran tumor sebelum kemoterapi menunjukkan peningkatan lebih tinggi pada AMH setelah kemoterapi.Kesimpulan: Terjadi penurunan kadar AMH dan ß-hCG setelah tiga siklus kemoterapi MTX pada wanita dengan GTD risiko rendah. Ukuran tumor dan kadar ß-hCG berkorelasi dengan hasil kadar AMH setelah kemoterapi.Kata kunci: Kemoterapi, Metotreksat, Hormon anti-mullerian, ß-hCG, Tumor trofoblas gestasional
Pembuatan Aplikasi Kamus Ilmu Komunikasi Berbasis Smartphone sebagai Media Pembelajaran Mandiri
Authors: Nurjayanti
Published: March 2024

Aplikasi kamus digital kini kian marak dikembangkan oleh pihak pengembang (developer) aplikasi untuk tujuan pendidikan. Aplikasi kamus yang dibuat dan dikembangkan tersebut, secara spesifik bertujuan sebagai media belajar masyarakat secara umum dalam berbagai bidang ilmu. Sejauh ini, belum adanya aplikasi serupa yang dirancang untuk memenuhi kebutuhan pengguna pada bidang Ilmu Komunikasi. Maka dipandang perlu untuk membuat dan mengembangkan aplikasi kamus istilah Ilmu Komunikasi yang berbasis smartphone dengan tujuan sebagai media belajar mandiri. Metode yang digunakan dalam merancang aplikasi Kamus Ilmu Komunikasi ialah pengembangan R&D (Research and Development), yang terdiri atas 7 tahapan. Salah satu tahapan ialah uji coba yang menggunakan metode statistik deskriptif untuk mengukur kepuasan pengguna aplikasi Kamus Ilmu Komunikasi. Hasil dari kegiatan ini ialah sebuah produk berbentuk aplikasi berbasis smartphone yang diberi nama Kamus Ilmu Komunikasi. Berdasarkan hasil uji coba pada aplikasi tersebut, diperoleh hasil dapat memenuhi harapan dan kebutuhan pengguna sebagai media belajar mandiri, khususnya bagi mahasiswa yang sedang mempelajari Ilmu Komunikasi.
From the sciences to humanism in the design
Authors:   UNIVERSIDAD AUTÓNOMA METROPOLITANA UNIDAD CUAJIMALPA, Rodríguez Morales Luis Alfredo
Published: March 2024

"he paradigm of Modern Design defines its contours in the first decades of the 20th century. Like any other, this was a process in which different people participated and that synthesized various currents, along which a guiding axis prevailed: rationality and, consequently, the application of structured methods to the process of configuring objects. Towards the 1980s, the paradigm of the Modern Movement began to be questioned, due both to the evolution of the discipline itself and to the pressure of external factors among which the accelerated process of globalization, the strengthening of neoliberal economics, the growing importance of minorities and the technological change towards digital."
Effect of dressing with different antiseptic agents on reproductive parameters in rats undergoing abdominal incision
Authors: Akarsu G.D. , Erbaş E. , Akarsu S.A.
Published: March 2024

Antiseptic agents used in the postoperative period affect the functions of many tissues in the body, including the testicles. In this study, the effect of dressings administered with different antiseptic agents on testicular functions in rats that underwent abdominal incisions was investigated. A total of 48 Sprague-Dawley rats were used in the study. Each of the rats in the study group underwent a 4 cm-long skin and muscle operation. The incision was then stitched immediately. Antiseptics, hemp seed oil, hemp leaf oil, and cannabidiol oil were then administered to the rats for 10 days to provide antisepsis. The rats were sacrificed 24 hours after the last administration, and testicular tissues were removed. Testicular tissues were used for histopathological examination and biochemical analysis, while epididymal tissue was used for sperm analysis. According to the results, the MDA level in the antiseptic-administered group was higher than in the other experimental groups (p<0.05). Levels of SOD, CAT activities, and GSH content were found to be lower in the antiseptic group than in the hemp seed oil, hemp leaf oil, and cannabidiol oil groups (p<0.05). In testicular histology, the SEED group had the highest Johnsen score, and the antiseptic group had the lowest score (p<0.05). While JAK, P-JAK2, STAT3, PSTAT3, and NF-κB were generally higher in the antiseptic group compared to the other groups, they were lower in the SEED group. Additionally, sperm total motility rate and epididymal sperm density were highest in the SEED group (p<0.05). As a result, it was determined that cannabidiol seed oil had a good effect on testicular histology and sperm quality in male rats during the wound healing process.
Combined antimicrobial action of streptomycin and terpenes against atypical mycobacteria isolated from fish
Authors: Guz L. , Puk K. , Szwajgier D. , Pastuszka A.
Published: March 2024

The aim of this study was to investigate the antimycobacterial activity of 39 free terpenes and their activity in combination with streptomycin. Antimicrobial activity was first evaluated by screening 39 free terpenes at concentrations from 1.56 to 400 μg/mL. None of these exhibited positive effects against any of the nontuberculous mycobacteria (NTM) strains tested. However, six of the 39 terpenes (isoeugenol, nerol, (+)-α-terpineol, (1R)-(−)-myrtenol, (+)-terpinen-4-ol, and eugenol) were shown to enhance the activity of streptomycin against the NTM strains isolated from diseased ornamental fish.
Surgery combined with orthodontic treatment for bilateral horizontally impacted mandibular second molars: A case report
Authors: Li Kongliang , Wang Tingting , Bai Xueqin
Published: March 2024

Surgery combined with orthodontic uprighting of impacted mandibular second molars requires sequential treatment procedures. This article presents a rare case of horizontally impacted bilateral mandibular second molars accompanied by dental crowding. The patient’s mandibular second molars were fully embedded in bone with overlying mesially-impacted mandibular third molars and the mandibular first molars were inclined distally. The treatment involved staged bilateral extraction of the second premolars and mandibular third molars, followed by the surgical implantation of micro-implants for anchorage in the mandibular ramus. At a subsequent stage, the mandibular second molars were successfully orthodontically uprighted, leading to a favourable treatment outcome.
Depth distribution of plant-parasitic nematodes on bentgrass golf greens in Missouri and Indiana
Authors: McCurdy Asa L. , Barizon Jefferson , Miller G.L.
Published: March 2024

Control of plant-parasitic nematodes (PPNs) on golf putting greens with nematicides is dependent on the seasonal occurrence and depth distribution of target PPN populations. This study aimed to determine if plant-parasitic nematode populations on golf course putting greens in Missouri and Indiana peaked at a targetable depth at a specific time in the year, focusing primarily on lance (Hoplolaimus spp.) and root-knot (Meloidogyne spp.) nematodes. To elucidate species diversity in the region, rDNA from a subset of lance and root-knot nematodes was sequenced and analyzed, with additional micromorphology of a lance nematode assessed in scanning electron micrographs (SEM). Soil samples were taken to a depth of 25 cm and stratified into 5 cm increments during April, June, August and October at seven sites across Missouri, three in the Kansas City metro of Kansas in 2021 and in ten sites across Indiana in 2022. Samples were stratified in five-centimeter increments and aggregated for a total of 100 cm3 of soil at each depth for each sampling. Samples were processed using a semi-automatic elutriator followed by the sucrose-flotation method, and populations were counted using a hemocytometer and recorded. For molecular characterization, rDNA was extracted and analyzed from 31 individual lance nematodes from one site in Missouri and eight sites in Indiana, and 13 root-knot nematodes from nine sites across Indiana. A significant interaction occurred between sampling month and depth for lance and ring nematodes Missouri/KS, with both PPN populations peaking at the 0–5 cm depth during October, which is well after most targeted nematicide applications are applied. Ring nematodes in Indiana did not follow this trend and were most abundant in August at a depth of 0–5 cm. No significant interaction between depth and month occurred for lance or root-knot nematodes in Indiana, or root-knot nematodes in Missouri/KS. Hoplolaimus stephanus and H. magnistylus were the lance species identified on golf greens, and Meloidogyne naasi, M. graminicola and M. marylandi were the root-knot species identified. Scanning-electron micrographs confirmed morphological characteristics unique to H. stephanus.
Effectiveness of Nutritional Intervention Led by Clinical Dietitian in Patients at Risk of Malnutrition at the Primary Healthcare Level in Slovenia - Evaluation Study
Authors: Mlakar-Mastnak Denis , Blaž Kovač Milena , Terčelj Mila , Uhan Samo , Majdič Neža , Rotovnik Kozjek Nada
Published: March 2024

Introduction

Clinical dietitians play a crucial role in the nutritional support of patients at risk of malnutrition in primary care settings. The study aimed to evaluate the effect of an individualized nutritional intervention on clinically relevant outcomes for patients with chronic disease at nutritional risk.

Methods

A longitudinal evaluation study was conducted in two Slovenian primary health centres. We used pre-test and post-test design. Patients with chronic disease were screened using the Malnutrition Universal Screening Tool and additional risk factors (≥70 years and BMI <22 kg/m2; lower food intake in the last five days). Patients at nutritional risk were referred to a clinical dietitian for individual nutritional intervention. The effect of the nutritional intervention was assessed six months after the patients’ first visit with a clinical dietitian.

Results

The sample included 94 patients. Nutritional risk was reduced significantly in high-risk and moderate-risk patients. In a subgroup of patients with a MUST score ≥1 (77 patients), body weight, BMI, Fat-Free Mass Index (FFMI), energy intake, and protein intake increased significantly (p<0.001). At the same time, the phase angle significantly increased (p<0.001), but there were no statistically significant changes in the improvement of grip strength. In a subgroup of patients with MUST score 0 (17 patients), we observed an increase in their median daily energy intake (p<0.001) and median protein intake (p=0.003).

Conclusion

Nutritional intervention delivered by a clinical dietitian improved patients’ nutritional intake and nutritional and functional status.
Pengembangan Kawasan Wisata Air Terjun Pria Laot, Sabang
Authors: Irayana Cut Tasya , Zainuddin Zainuddin , Yusuf Myna Agustina
Published: March 2024

Abstrak Wisata pegunungan Air Terjun Pria Laot memiliki panorama alam yang asri dan memiliki udara yang bersih ditengah hutan. Saat ini sarana pariwisata pada kawasan wisata Air Terjun Pria Laot belum dapat digunakan sepenuhnya oleh pengunjung. Tujuan penelitian ini adalah untuk mengetahui kondisi eksisting dan memberikan arahan pengembangan sarana dan prasarana obyek wisata Air Terjun Pria Laot. Metode penelitian ini menggunakan analisis deskriptif dan analisis SWOT dari hasil pengumpulan data primer yang dilakukan dengan observasi, wawancara serta data sekunder yang dikumpulkan dari bahan bacaan. Hasil yang didapatkan adalah kondisi eksisting kawasan wisata Air Terjun Pria Laot memiliki atraksi wisata yang indah dan alami,namun kondisi jalan harus dilakukan perbaikan, ketersediaan transportasi umum sangat minim, tempat parkir dan kamar ganti/toilet belum sesuai dengan Peraturan Menteri, belum adanya sistem pengelolaan sampah dan tidak adanya paket wisata yang melayani perjalanan ke obyek wisata. Strategi prioritas berdasarkan SWOT adalah menambahkan pengembangan kawasan wisata Air Terjun Pria Laot dalam rencana Pemerintah Kota Sabang, meningkatkan kualitas, perbaikan dan pengadaan terhadap sarana serta melakukan promosi objek wisata air terjun.A
Perancangan Pusat Rehabilitasi Psikiatri di Aceh Tengah
Authors: Putri Nabila Chantika , Ridwan Nasrullah , Nasution Burhan
Published: March 2024

Rehabilitasi Psikiatri adalah cabang ilmu yang mempunyai tujuan untuk menolong pasien yang memerlukan perilaku atau tanganan khusus yang mengalami gangguan mental seperti gangguan obsesif kompulsif, atau gangguan bipolar dengan berbagai macam cara agar pasien dapat kembali diterima dan berbaur didalam masyarakat. Indonesia National Adolescent Mental Health Survey (I-NAMHS), survey Kesehatan mental yang meneliti pertama pada remaja 10-17 tahun menunjukkan bahwa satu dari 3 remaja Indonesia memiliki gangguan Kesehatan mental dan satu dari dua puluh remaja Indonesia memiliki gangguan mental dalam 12 bulan terakhir. Seimbang dengan 15,5 juta dan 2,45 juta remaja. Hal yang menjadi penyebab utama dari meningkatnya masyarakat dengan gangguan mental emosional dikarenakan negara belum memberikan fasilitas psikiatris yang layak. Studi menunjukkan bahwa lebih dari 85% orang dengan gangguan jiwa di negara-negara berkembang tidak memiliki akses ke layanan kesehatan jiwa (Ayuningtias, 2019). Oleh karena itu dibutuhkan fasilitas khusus rehabilitasi untuk memberikan lingkungan yang kondusif bagi proses tahap penyembuhan pasien. Penelitian mendukung bahwa ketika kamar pasien memiliki pemandangan alam, masa inap pasca operasi umumnya lebih pendek, lebih sedikit obat penghilang rasa sakit, dan kondisi keseluruhan membaik. Bukti menunjukkan bahwa gambaran representasional dari fitur alami seperti lanskap, kebun, dan perairan dapat mengurangi stres dan meningkatkan hasil seperti menghilangkan rasa sakit. Salah satu factor penting dalam proses pemulihan adalah lingkungan, sehingga menerapkan tema Biophilic Architecture yang mana tujuan dari tema tersebut adalah memberikan kesempatan terhadap manusia untuk hidup di tempat yang minim tempat stress . dengan mengintegrasikan desain dengan alam, prinsipnya yaitu nature of the space, nature in the space dan nature analogues. Fasilitas rehabilitasi yang ada di Aceh sangat minim, semua rujukan tertuju pada Rumah Sakit Jiwa di Kota Banda Aceh. Untuk itu, pusat rehabilitasi dengan fasilitas lengkap perlu adanya. Lokasi yang sesuai dengan psikologi manusia dalam hal ketenangan adalah lokasi yang berada di dekat air, dan dipenuhi pegunungan disekitarnya, seperti di Aceh Tenga
Penerapan Konsep Arsitektur Biofilik Pada Perancangan Asrama Mahasiswa USK di Kota Banda Aceh
Authors: Zulfikri Zulfikri , Djamaluddin Masdar , Muliadi Muliadi
Published: March 2024

Universitas Syiah Kuala menjadi salah satu kampus pilihan mahasiswa yang ingin melanjutkan studi ke jenjang yang lebih tinggi. Setiap tahunnya kampus akan mengadakan ujian tulis berbasis komputer (UTBK) untuk menyeleksi mahasiswa terpilih yang akan diterima melanjutkan pendidikan berdasarkan prodi pilihan mahasiswa tersebut. Selain itu, terdapat beasiswa khusus bagi mahasiswa baru yang kurang mampu yaitu beasiswa KIP-K. Mahasiswa yang telah dinyatakan lulus di Universitas Syiah Kuala dengan beasiswa KIP-K memiliki kewajiban khusus untuk tinggal di asrama selama satu tahun. Mahasiswa KIP-K yang tinggal di asrama selama satu tahun memiliki kebutuhan tersendiri untuk menjalani kegiatan rutin di setiap hari. Namun, fasilitas yang tersedia pada asrama masih belum maksimal. Kondisi bangunan dan lingkungan juga belum maksimal dalam menghadirkan rasa sejuk dan nyaman. Perancangan ini menerapkan tema arsitektur biofilik dengan 14 prinsip desain khusus berdasarkan buku karya dari Terrapin Bright Green untuk menyelesaikan setiap masalah yang ada di dalam ruang lingkup asrama mahasiswa USK. Tema ini digunakan agar kesan asrama USK dan lingkungan dapat menyatu dan saling mendukung aktivitas yang dilakukan di dalam bangunan maupun diluar bangunan. Menghadirkan fasilitas pendukung berupa minimarket, apotek klinik, gedung serbaguna, laundry koin, fotocopy ATK, kantin, depot air isi ulang, dan taman agar mahasiswa dapat beraktifitas dengan maksimal dan nyaman.
Penerapan Tema Cultural Symbol pada Perancangan Museum Seni Rupa di Banda Aceh
Authors: Luqyana Ghina , Muslimsyah Muslimsyah , Muftiadi Muftiadi
Published: March 2024

Seni rupa adalah cabang seni yang dapat dinikmati secara visual dan dapat dirasakan dengan rabaan sehingga perlu dikembangkan sebagai kekayaan negara. Aceh merupakan salah satu wilayah yang menghasilkan karya seni dan budaya dengan ciri khas berbeda. Banyaknya modifikasi seni rupa terindikasi kepunahan identitas. Budaya tradisional yang bersifat sosiokomunal-spiritual bersifat individualistik dan pragmatik, sehingga muncul arsitektur simbolisme yang merupakan subjek atau tema dari mahakarya arsitektur yang tidak hanya bertujuan dalam pemenuhan fungsi, tetapi menjaga citra atau pandangan dan makna. Perancangan Museum Seni Rupa di Kota Banda Aceh bertujuan untuk melestarikan karya seni dan budaya melalui koleksi historikal sekaligus wadah informasi, edukatif dan rekreatif untuk generasi mendatang dengan aplikasi tema Cultural Symbol. Metode perancangan yang digunakan terdiri dari: studi objek perancangan, studi lokasi, studi tema, analisis perancangan fungsional, dan konsep perancangan. Lokasi perancangan berada di Jalan Taman Sri Ratu Safiatuddin, yaitu jalan kolektor Kota Banda Aceh. Perancangan Museum Seni Rupa di Banda ini memperhatikan perspektif analogi Cultural Symbol kebudayaan Aceh yang diimplemetasikan kedalam bentuk bangunan. Tema Cultural Symbol digunakan dalam konsep perancangan agar menyampaikan citra/kesan dan makna pada objek pada bangunan tersebut sebagai identitas dan ciri budaya serta membuat masyarakat dengan mudah mengidentifikasi citra dan fungsi dari suatu bangunan.
Pendekatan Holistik Perancangan Graha Widya Widigda (Pendidikan Karakter Pancasila) Bagi Pelajar Tingkat Dasar Dikabupaten Malang
Authors: Ramadhayanti Faddilla Lindra , Santoso Joko , Bintarjo Benny
Published: March 2024

Karakter menjadi suatu hal dalam diri manusia yang dapat dirasakan lalu ditimbang sebagai tolak ukur kebaikan seorang manusia yang selanjutnya akan mendapatkan balasan sesuai dengan yang telah ditunjukan. Dengan isu tersebut maka perlu dibuatlah sebuah arena terutama untuk anak usia sekolah dasar sebagai sarana pembelajaran dasar dalam pengarahan anak kepada karakter baik yang berlandaskan nasionalisme sebagai siswa berkarakter Pancasila. Agar pembelajaran tersebut dapat berjalan maka dengan penelusuran secara mendetail mulai dari latar belakang hingga analisa ditemukanlah konsep bangunan yang tepat dengan mengusung pendekatan Holistik di dalamnya. Yang mana Arsitektur Holistik ini berbicara tentang spiritual, emosional,vital, dan material. Sedangkan konsep yang akan kami usung adalah Asrikan Pancasila tanpa menhilangkan cirikhas dari kota tersebut. Diharapkan para pengunjung dapat menerapkan dampak positif seusai kedatanganya dan dapat ditularkan kepada lingkunganya. Agar banyak generasi yang akan datang dapat menjadi individu yang lebih baik dari pendahulunya. Pendekatan holistic ini lah yang menjadi sumber terbentuknya konsep bangunan karena pada bangunan ini mengusung bentuk dan makna bangunan secara kental, mulai dari bentuk bangunan yang oval, memiliki ruang kosong pada bagian tengah sebagai pengaturan emosi hingga dibuatnya bangunan dengan lapisan berbentuk barrier antara ruang luar dan dalam untuk dapat membuat sebuah rute perjalanan antar ruang yang berlanjut hingga akhir tujuan. Hampir seluruh unsur pada pendekatan holistic Menurut Hozman, Oldrich kami masukkan pada bangunan utama yang letaknya berada di tengah sebagai center point dari seluruh area Graha Widya Widigda.