bluuebunny/crossref_metadata_2025 huggingface dataset:
Posttraumatic Haematuria with Pseudorenal Failure: A Diagnostic Lead for Intraperitoneal Bladder Rupture
Authors: Vagholkar Ketan , Vagholkar Suvarna
Published: July 2016

Bladder rupture is a very morbid injury following blunt or penetrating lower abdominal trauma. Prompt diagnosis is crucial to initiate optimal treatment. Intraperitoneal bladder rupture is associated with haematuria and biochemical features of renal failure. Cystogram is diagnostic. Immediate open surgical repair is the main stay of treatment. A case of intraperitoneal rupture diagnosed preoperatively by the presence of haematuria and pseudorenal failure is presented to highlight the association of posttraumatic haematuria and pseudorenal failure in such injuries.
A New Relationship between Block Designs
Authors: Shramchenko Alexander , Shramchenko Vasilisa
Published: July 2016

We propose a procedure of constructing new block designs starting from a given one by looking at the intersections of its blocks with various sets and grouping those sets according to the structure of the intersections. We introduce a symmetric relationship of friendship between block designs built on a set V and consider families of block designs where all designs are friends of each other, the so-called friendly families. We show that a friendly family admits a partial ordering. Furthermore, we exhibit a map from the power set of V, partially ordered by inclusion, to a friendly family of a particular type which preserves the partial order.
Authentication ofCoffea arabicaaccording to Triacylglycerol Stereospecific Composition
Authors: Cossignani L. , Montesano D. , Simonetti M. S. , Blasi F.
Published: July 2016

Stereospecific analysis is an important tool for the characterization of lipid fraction of food products. In the present research, an approach to characterizearabicaandrobustavarieties by structural analysis of the triacylglycerol (TAG) fraction is reported. The lipids were Soxhlet extracted from ground roasted coffee beans with petroleum ether, and the fatty acids (FA) were determined as their corresponding methyl esters. The results of a chemical-enzymatic-chromatographic method were elaborated by a chemometric procedure, Linear Discriminant Analysis (LDA). According to the total and intrapositional FA composition of TAG fraction, the obtained results were able to characterize roasted pure coffee samples and coffee mixtures with 10%robustacoffee added toarabicacoffee. Totally correct classified samples were obtained when the TAG stereospecific results of the considered coffee mixture (90 : 10arabica/robusta) were elaborated by LDA procedure.
ETSI-Standard Reconfigurable Mobile Device for Supporting the Licensed Shared Access
Authors: Kim Kyunghoon , Jin Yong , Kum Donghyun , Choi Seungwon , Mueck Markus , Ivanov Vladimir
Published: July 2016

In order for a Mobile Device (MD) to support the Licensed Shared Access (LSA), the MD should be reconfigurable, meaning that the configuration of a MD must be adaptively changed in accordance with the communication standard adopted in a given LSA system. Based on the standard architecture for reconfigurable MD defined in Working Group (WG) 2 of the Technical Committee (TC) Reconfigurable Radio System (RRS) of the European Telecommunications Standards Institute (ETSI), this paper presents a procedure to transfer control signals among the software entities of a reconfigurable MD required for implementing the LSA. This paper also presents an implementation of a reconfigurable MD prototype that realizes the proposed procedure. The modem and Radio Frequency (RF) part of the prototype MD are implemented with the NVIDIA GeForce GTX Titan Graphic Processing Unit (GPU) and the Universal Software Radio Peripheral (USRP) N210, respectively. With a preset scenario that consists of five time slots from different signal environments, we demonstrate superb performance of the reconfigurable MD in comparison to the conventional nonreconfigurable MD in terms of the data receiving rate available in the LSA band at 2.3–2.4 GHz.
Refractory Hypotension as an Initial Presentation of Bilateral Subclavian Artery Stenosis
Authors: Afari Maxwell Eyram , Wylie John V. , Carrozza Joseph P.
Published: July 2016

Bilateral subclavian stenosis is a rare clinical condition. An interbrachial pressure difference of 15 mm Hg can raise suspicion for unilateral subclavian artery stenosis, but the diagnosis of bilateral subclavian artery stenosis can be challenging. We present a case of a 75-year-old woman who presented with refractory hypotension after surgery. Initial vitals revealed blood pressure in the 60s/50s mm Hg in both arms. Cardiopulmonary examination was remarkable for diminished pulses in all 4 extremities and audible carotid bruits. She continued to be hypotensive despite aggressive fluid resuscitation. Troponin T peaked at 0.24 ng/mL (reference < 0.04), and an echocardiogram revealed a reduction in ejection fraction (37% from 50%). Left and right heart catheterization demonstrated normal filling pressures and cardiac output. During the procedure, however, it was noted that the patient’s central blood pressure was 70–80 mm Hg higher than cuff pressures obtained in either arm. Selective angiography revealed 90% left subclavian ostial stenosis as well as 70% stenosis of the right subclavian artery.
PD-1/PD-L1 Blockade Enhances T-cell Activity and Antitumor Efficacy of Imatinib in Gastrointestinal Stromal Tumors
Authors: Seifert Adrian M. , Zeng Shan , Zhang Jennifer Q. , Kim Teresa S. , Cohen Noah A. , Beckman Michael J. , Medina Benjamin D. , Maltbaek Joanna H. , Loo Jennifer K. , Crawley Megan H. , Rossi Ferdinand , Besmer Peter , Antonescu Cristina R. , DeMatteo Ronald P.
Published: July 2016

Purpose: Tyrosine kinase inhibitors are effective in gastrointestinal stromal tumors (GISTs) but often are of transient benefit as resistance commonly develops. Immunotherapy, particularly blockade of the inhibitory receptor programmed death 1 (PD-1) or the ligand programmed death ligand 1 (PD-L1), has shown effectiveness in a variety of cancers. The functional effects of PD-1/PD-L1 blockade are unknown in GISTs.

Experimental Design: We analyzed tumor and matched blood samples from 85 patients with GISTs and determined the expression of immune checkpoint molecules using flow cytometry. We investigated the combination of imatinib with PD-1/PD-L1 blockade in KitV558Δ/+ mice that develop GISTs.

Results: The inhibitory receptors PD-1, lymphocyte activation gene 3, and T-cell immunoglobulin mucin-3 were upregulated on tumor-infiltrating T cells compared with T cells from matched blood. PD-1 expression on T cells was highest in imatinib-treated human GISTs. Meanwhile, intratumoral PD-L1 expression was variable. In human GIST cell lines, treatment with imatinib abrogated the IFNγ-induced upregulation of PD-L1 via STAT1 inhibition. In KitV558Δ/+ mice, imatinib downregulated IFNγ-related genes and reduced PD-L1 expression on tumor cells. PD-1 and PD-L1 blockade in vivo each had no efficacy alone but enhanced the antitumor effects of imatinib by increasing T-cell effector function in the presence of KIT and IDO inhibition.

Conclusions: PD-1/PD-L1 blockade is a promising strategy to improve the effects of targeted therapy in GISTs. Collectively, our results provide the rationale to combine these agents in human GISTs. Clin Cancer Res; 23(2); 454–65. ©2016 AACR.
PD-1 Axis Inhibitors in EGFR- and ALK-Driven Lung Cancer: Lost Cause?
Authors: Gettinger Scott , Politi Katerina
Published: July 2016

Programmed death axis 1 (PD-1) inhibitors have ushered in a new error of cancer immunotherapeutics for advanced smoking-associated non–small cell lung cancer. Their role in treating EGFR-mutant and ALK-rearranged lung cancer has yet to be determined. Clin Cancer Res; 22(18); 4539–41. ©2016 AACR.

See related article by Gainor et al., p. 4585
Incomplete Annular Pancreas with Ectopic Opening of the Pancreatic and Bile Ducts into the Pyloric Ring: First Report of a Rare Anomaly
Authors: Kobayashi Shinjiro , Hoshino Horoyuki , Segami Kouhei , Koizumi Satoshi , Ooike Nobuyuki , Otsubo Takehito
Published: July 2016

The patient was a 56-year-old woman who had experienced epigastralgia and dorsal pain several times over the last 20 years. She was admitted for a diagnosis of acute cholecystitis, and severe intra- and extrahepatic bile duct dilatation with inner air density was noted. No papilla of Vater was present in the descending duodenum, and 2 small holes were present in the pyloric ring. Bile excretion from one of the small holes was observed under forward-viewing endoscope. It was considered that the pancreatic and bile ducts separately opened into the pyloric ring. Based on these findings, malformation of the pancreaticobiliary duct was diagnosed. She did not wish treatment, but the obstruction associated with duodenal stenosis was noted after 2 years. Pancreatoduodenectomy was performed as curative treatment for duodenal stenosis and retrograde biliary infection through the bile duct opening in the pyloric ring. The ventral pancreas encompassed almost the entire circumference of the pyloric ring, suggesting a subtype of annular pancreas. Generally, lesions are present in the descending part of the duodenum in an annular pancreas, and the pancreatic and bile ducts join in the papillary region. However, in this patient, (1) the pancreas encompassed the pyloric ring, (2) the pancreatic and bile ducts opened separately, and (3) the openings of the pancreatic and bile ducts were present in the pyloric ring. The pancreas and biliary tract develop through a complex process, which may cause various types of malformation of the pancreaticobiliary system, but no similar case report was found on a literature search. This case was very rare and could not be classified in any type of congenital anomaly of the pancreas. We would classify it as a subtype of annular pancreas with separate ectopic opening of the pancreatic and bile ducts into the pyloric ring.
Navigated Percutaneous Lung Ablation under High-Frequency Jet Ventilation of a Metastasis from a Wilms’ Tumour: A Paediatric Case Report
Authors: Freedman Jacob , Harbut Piotr
Published: July 2016

This is a case report of microwave energy being used to ablate an inoperable metastasis of a Wilms’ tumour in a 6-year-old boy using state-of-the-art navigated computed tomography targeting and high-frequency jet ventilation to reduce organ displacement and the potential risk of procedure-related pneumothorax. After the ablation, the young boy had high-dose chemotherapy followed by an autologous stem cell transplantation with rapid reduction of three recurrent right-sided lung metastases.
Necitumumab plus Gemcitabine and Cisplatin as First-Line Therapy in Patients with Stage IV EGFR- Expressing Squamous Non-Small-Cell Lung Cancer: German Subgroup Data from an Open-Label, Randomized Controlled Phase 3 Study (SQUIRE)
Authors: Reck Martin , Thomas Michael , Kropf-Sanchen Cornelia , Mezger Jörg , Socinski Mark A. , Depenbrock Henrik , Soldatenkova Victoria , Brown Jacqueline , Krause Thomas , Thatcher Nick
Published: July 2016

Background: In the SQUIRE study, adding the anti-epidermal growth factor receptor (EGFR) IgG1 antibody necitumumab to first-line gemcitabine and cisplatin (GC + N) in advanced squamous non-small-cell lung cancer (sqNSCLC) significantly improved overall survival (OS); the safety profile was acceptable. We explored data for the German subpopulation (N = 96) of SQUIRE patients with EGFR-expressing tumors. Patient and Methods: Patients with stage IV sqNSCLC were randomized 1:1 to up to 6 cycles of open-label GC + N or GC alone. GC + N patients with no progression continued on necitumumab monotherapy until disease progression or intolerable toxicity. The primary endpoint was OS; the secondary endpoints included progression-free survival (PFS), safety and health-related quality of life (EQ-5D, Lung Cancer Symptom Scale (LCSS)). Results: The 96 German SQUIRE patients with EGFR-expressing tumors (GC + N 42, GC 54) received a median of 4 GC cycles; the GC + N patients received 5 cycles of necitumumab. Adding necitumumab was associated with 41% risk reduction of death (hazard ratio (HR) 0.59, 95% confidence interval (CI) 0.37-0.94, p = 0.026) and 44% risk reduction of progression (HR 0.56, 95% CI 0.33-0.95, p = 0.029). Adverse events typically associated with EGFR antibody treatment (including rash, hypomagnesemia) were more common with GC + N. The time to deterioration of the EQ-5D and LCSS scores showed no notable differences between the treatment arms, except for appetite loss (delayed for GC + N). Conclusion: The survival benefit from adding necitumumab to first-line GC was more pronounced in the German SQUIRE subpopulation with EGFR-expressing tumors than in the overall (intention-to-treat) population; toxicity was manageable and consistent with the overall population.
Effect of Preoperative Nutritional Status on Surgical Site Infection in Colorectal Cancer Resection
Authors: Tanaka Toshimichi , Sato Takeo , Yamashita Keishi , Hosoda Kei , Nakamura Takatoshi , Watanabe Masahiko
Published: July 2016

Background/Aims: Postoperative complications of colorectal cancer (CRC) can sometimes be life threatening. Prevention of morbidity is therefore the most important issue, and among such complications, surgical site infections (SSIs) are the most critical. Predictive factors for SSI were evaluated. Patients and Methods: This was a retrospective study of 432 patients with CRC. SSIs were classified into incisional SSIs (iSSIs) and organ/space SSIs (o/sSSIs). Results: Preoperative serum albumin (relative risk (RR) 2.51, p = 0.01) and body mass index (BMI: RR 2.36, p = 0.02) were the independent risk factors for iSSIs, while rectal cancer (RR 6.34, p < 0.0001), preoperative serum albumin (RR 7.03, p = 0.004), age (RR 2.71, p = 0.02), and male sex (RR 2.41, p = 0.05) were the independent risk factors for o/sSSIs. Patients with both low serum albumin and high BMI had the highest incidence of iSSIs (34.2%), and the group with rectal cancer and low serum albumin had the highest incidence of o/sSSIs (57.1%). Conclusions: Preoperative nutritional status is a risk factor for SSIs in CRC, and its proper preoperative management may reduce the risk of SSIs.
Primeiros ventos olímpicos em terras tupiniquins
Authors: Melo Victor Andrade de , Peres Fabio de Faria
Published: July 2016

Este artigo objetiva discutir as primeiras vinculações estabelecidas com os Jogos Olímpicos no Brasil. Inicialmente, analisamos os diversos usos do termo no Rio de Janeiro do século XIX. Posteriormente, debatemos as mudanças ocasionadas em função da maior participação de atletas brasileiros em contendas internacionais, inclusive em virtude da conquista das pioneiras medalhas olímpicas. Por fim, nos debruçamos sobre a promoção de uma importante competição no país (1922), procurando extrair breves reflexões sobre a organização desses eventos.
“Tá tranquilo, tá favorável”: a cobertura brasileira dos Jogos Olímpicos do Rio de Janeiro 2016
Authors: Marques José Carlos
Published: July 2016

Os Jogos Olímpicos de Barcelona 1992 parecem ter inaugurado um novo paradigma na organização desse tipo de megaevento – seja pela cobertura midiática, seja pelas soluções que os organizadores locais procuraram divulgar sobre a competição. Talvez motivado por essas questões, o sociólogo francês Pierre Bourdieu (1930-2002) publicou em 1994 o artigo “Os Jogos Olímpicos”, apresentado numa conferência em outubro de 1992 em Berlim (Alemanha). Este texto colocará em perspectiva, tendo em vista a cobertura dos Jogos Olímpicos do Rio de Janeiro 2016, as reflexões de Bourdieu a partir desse e de outros textos em que ele e demais intelectuais europeus colocam em xeque o trabalho da imprensa em torno do esporte.
Interaction Between HIV-1 Nef and Calnexin
Authors: Hunegnaw Ruth , Vassylyeva Marina , Dubrovsky Larisa , Pushkarsky Tatiana , Sviridov Dmitri , Anashkina Anastasia A. , Üren Aykut , Brichacek Beda , Vassylyev Dmitry G. , Adzhubei Alexei A. , Bukrinsky Michael
Published: July 2016

Objective—

HIV-infected patients are at an increased risk of developing atherosclerosis, in part because of downmodulation and functional impairment of ATP-binding cassette A1 (ABCA1) cholesterol transporter by the HIV-1 protein Nef. The mechanism of this effect involves Nef interacting with an ER chaperone calnexin and disrupting calnexin binding to ABCA1, leading to ABCA1 retention in ER, its degradation and resulting suppression of cholesterol efflux. However, molecular details of Nef–calnexin interaction remained unknown, limiting the translational impact of this finding.

Approach and Results—

Here, we used molecular modeling and mutagenesis to characterize Nef–calnexin interaction and to identify small molecule compounds that could block it. We demonstrated that the interaction between Nef and calnexin is direct and can be reconstituted using recombinant proteins in vitro with a binding affinity of 89.1 nmol/L measured by surface plasmon resonance. The cytoplasmic tail of calnexin is essential and sufficient for interaction with Nef, and binds Nef with an affinity of 9.4 nmol/L. Replacing lysine residues in positions 4 and 7 of Nef with alanines abrogates Nef–calnexin interaction, prevents ABCA1 downregulation by Nef, and preserves cholesterol efflux from HIV-infected cells. Through virtual screening of the National Cancer Institute library of compounds, we identified a compound, 1[(7-oxo-7H-benz[de]anthracene-3-yl)amino]anthraquinone, which blocked Nef–calnexin interaction, partially restored ABCA1 activity in HIV-infected cells, and reduced foam cell formation in a culture of HIV-infected macrophages.

Conclusion—

This study identifies potential targets that can be exploited to block the pathogenic effect of HIV infection on cholesterol metabolism and prevent atherosclerosis in HIV-infected subjects.
Alternative Splicing of Titin Restores Diastolic Function in an HFpEF-Like Genetic Murine Model (
Ttn
ΔIAjxn
)
Authors: Bull Mathew , Methawasin Mei , Strom Joshua , Nair Pooja , Hutchinson Kirk , Granzier Henk
Published: July 2016

Rationale:

Patients with heart failure with preserved ejection fraction (HFpEF) experience elevated filling pressures and reduced ventricular compliance. The splicing factor RNA-binding motif 20 (RBM20) regulates the contour length of titin’s spring region and thereby determines the passive stiffness of cardiomyocytes. Inhibition of RBM20 leads to super compliant titin isoforms (N2BAsc) that reduce passive stiffness.

Objective:

To determine the therapeutic potential of upregulating compliant titin isoforms in an HFpEF-like state in the mouse.

Methods and Results:

Constitutive and inducible cardiomyocyte-specific RBM20–inhibited mice were produced on a
Ttn
ΔIAjxn
background to assess the effect of upregulating compliant titin at the cellular and organ levels. Genetic deletion of the I-band–A-band junction (
IAjxn
) in titin increases strain on the spring region and causes a HFpEF-like syndrome in the mouse without pharmacological or surgical intervention. The increased strain represents a mechanical analog of deranged post-translational modification of titin that results in increased passive myocardial stiffness in patients with HFpEF. On inhibition of RBM20 in
Ttn
ΔIAjxn
mice, compliant titin isoforms were expressed, diastolic function was normalized, exercise performance was improved, and pathological hypertrophy was attenuated.

Conclusions:

We report for the first time a benefit from upregulating compliant titin isoforms in a murine model with HFpEF-like symptoms. Constitutive and inducible RBM20 inhibition improves diastolic function resulting in greater tolerance to exercise. No effective therapies exists for treating this pervasive syndrome; therefore, our data on RBM20 inhibition are clinically significant.
Incidence of Transient Ischemic Attack in Auckland, New Zealand, in 2011 to 2012
Authors: Barber P. Alan , Krishnamurthi Rita , Parag Varsha , Anderson Neil E. , Ranta Annemarei , Kilfoyle Dean , Wong Edward , Green Geoff , Arroll Bruce , Bennett Derrick A. , Witt Emma , Rush Elaine , Minsun Suh Flora , Theadom Alice , Rathnasabapathy Yogini , Te Ao Braden , Parmar Priyakumari , Feigin Valery L.
Published: July 2016

Background and Purpose—

There have been few recent population-based studies reporting the incidence (first ever) and attack rates (incident and recurrent) of transient ischemic attack (TIA).

Methods—

The fourth Auckland Regional Community Stroke study (ARCOS IV) used multiple overlapping case ascertainment methods to identify all hospitalized and nonhospitalized cases of TIA that occurred in people ≥16 years of age usually resident in Auckland (population ≥16 years of age is 1.12 million), during the 12 months from March 1, 2011. All first-ever and recurrent new TIAs (any new TIA 28 days after the index event) during the study period were recorded.

Results—

There were 785 people with TIA (402 [51.2%] women, mean [SD] age 71.5 [13.8] years); 614 (78%) of European origin, 84 (11%) Māori/Pacific, and 75 (10%) Asian/Other. The annual incidence of TIA was 40 (95% confidence interval, 36–43), and attack rate was 63 (95% confidence interval, 59–68), per 100 000 people, age standardized to the World Health Organization world population. Approximately two thirds of people were known to be hypertensive or were being treated with blood pressure–lowering agents, half were taking antiplatelet agents and just under half were taking lipid-lowering therapy before the index TIA. Two hundred ten (27%) people were known to have atrial fibrillation at the time of the TIA, of whom only 61 (29%) were taking anticoagulant therapy, suggesting a failure to identify or treat atrial fibrillation.

Conclusions—

This study describes the burden of TIA in an era of aggressive primary and secondary vascular risk factor management. Education programs for medical practitioners and patients around the identification and management of atrial fibrillation are required.
Inhibition of Thrombin-Activatable Fibrinolysis Inhibitor and Plasminogen Activator Inhibitor-1 Reduces Ischemic Brain Damage in Mice
Authors: Denorme Frederik , Wyseure Tine , Peeters Miet , Vandeputte Nele , Gils Ann , Deckmyn Hans , Vanhoorelbeke Karen , Declerck Paul J. , De Meyer Simon F.
Published: July 2016

Background and Purpose—

Cerebral ischemia and reperfusion is associated with activation of the coagulation cascade and fibrin deposition in cerebral microvessels. Both thrombin-activatable fibrinolysis inhibitor (TAFI) and plasminogen activator inhibitor-1 (PAI-1) attenuate fibrinolysis and are therefore attractive targets for the treatment of ischemic stroke.

Methods—

TAFI and PAI-1 were inhibited by monoclonal antibodies in a mouse model of transient middle cerebral artery occlusion. Twenty-four hours after stroke, mice were neurologically scored, cerebral thrombotic burden was assessed, and brain infarct sizes were calculated.

Results—

Inhibition of TAFI or PAI-1 significantly decreased cerebral infarct sizes by 50% 24 hours after stroke. This reduction in cerebral damage was associated with a significant decrease in fibrin(ogen) deposition in the ischemic brain. Concurrently, functional recovery of the animals was improved. Interestingly, combined targeting of TAFI and PAI-1 using low, and by themselves inactive, doses of antibodies improved cerebral blood flow and reduced cerebral fibrin(ogen) deposition and infarct sizes by 50%. When dual treatment was delayed to 1 hour after the start of reperfusion, it still reduced brain injury; however, this was not statistically significant.

Conclusions—

Targeting of PAI-1 and TAFI is protective in an ischemic stroke model by attenuating fibrin(ogen) deposition, thereby improving reperfusion. Combined inhibition has a co-operative effect that could become useful in ischemic stroke therapy.
WebAL Comes of Age: A Review of the First 21 Years of Artificial Life on the Web
Authors: Taylor Tim , Auerbach Joshua E. , Bongard Josh , Clune Jeff , Hickinbotham Simon , Ofria Charles , Oka Mizuki , Risi Sebastian , Stanley Kenneth O. , Yosinski Jason
Published: July 2016

We present a survey of the first 21 years of web-based artificial life (WebAL) research and applications, broadly construed to include the many different ways in which artificial life and web technologies might intersect. Our survey covers the period from 1994—when the first WebAL work appeared—up to the present day, together with a brief discussion of relevant precursors. We examine recent projects, from 2010–2015, in greater detail in order to highlight the current state of the art. We follow the survey with a discussion of common themes and methodologies that can be observed in recent work and identify a number of likely directions for future work in this exciting area.
A Sub-Geometric Skyphos from Borysthenes
Authors: Buiskikh Alla V.
Published: July 2016

In the Borysthenes collection a fragment of Sub-Geometric skyphos has come to light, which is most likely to have been manufactured in Miletus. The shape of the vessel and the stylistic features of its painted decoration enable us to date it to the second quarter of the 7th century bc. This skyphos, like other vessels in the Sub-Geometric style from barbarian sites in the North Pontic region, was taken there by colonists, who had founded the early apoikiai of Histria and Borysthenes. For this reason, vessels dating from the first half of the 7th century bc cannot be cited as evidence for pre-colonial ties having existed in the Pontic region.
On the Find of a Phalera Made from the Medallion of a Hellenistic Cup in Barrow No. 20 of the Noin-Ula Burial-Ground (Northern Mongolia)
Authors: Treister Mikhail
Published: July 2016

The paper explores a uniquephalera(horse brass) found in Noin-Ula Barrow No. 20 (Northern Mongolia). The form and decoration of the medallion, its style and the composition of the scene (depicting a satyr chasing a maenad – a subject which can be traced back to metal-working of the 4th centurybc) – show that thephaleramust have been made between the late-2nd or mid-1st centurybc, most probably in a Pontic workshop and from the medallion of a silver plate, aphialeor a conic cup, perhaps manufactured in Asia Minor in the second half of the 1st centurybc. Thephalerawas placed in a Hunnu burial-ground no later than in the middle of the 1st centuryad, since a Chinese lacquered cup dated to the fourth year of the Yuanyan Era (9bc) was found in the same grave. Thephalerais to date the easternmost find of Hellenistic silver plate.
New species of Mycena (Basidiomycota, Agaricales) from California
Authors: PERRY BRIAN A. , DESJARDIN DENNIS E.
Published: July 2016

Two new species of Mycena are described from California: Mycena nivicola, a spring taxon from the High Sierra Nevada and Cascade Ranges is proposed within section Hygrocyboideae, and M. bulliformis from the Coastal Ranges and Sierra Nevada Foothills is proposed in section Rubromarginatae. Both species are fully described, illustrated, and compared with similar and/or closely related taxa.
Two new species of the genus Stenichnus Thomson (Coleoptera, Staphylinidae, Scydmaeninae) from Zhejiang, East China
Authors: WANG DAN , LI LI-ZHEN
Published: July 2016

Two new species of the glandulariine genus Stenichnus are described: St. zhejiangensis sp. n. and St. donggonganus sp. n., both of which are discovered from Zhejiang Province, East China.
Receipt of Recommended Adolescent Vaccines Among Youth With Special Health Care Needs
Authors: McRee Annie-Laurie , Maslow Gary R. , Reiter Paul L.
Published: July 2016

We examined vaccination coverage among youth with special health care needs (YSHCN) using data from parents of adolescents (11-17 years) who responded to a statewide survey in 2010-2012 (n = 2156). Using a validated screening tool, we identified 29% of adolescents as YSHCN. Weighted multivariable logistic regression assessed associations between special health care needs and receipt of tetanus booster, meningococcal, and human papillomavirus (HPV) vaccines. Only 12% of youth had received all 3 vaccines, with greater coverage for individual vaccines (tetanus booster, 91%; meningococcal, 32%; HPV, 26%). YSHCN had greater odds of HPV vaccination than other youth (33% vs 23%, OR = 1.70, 95% CI = 1.16-2.50) but vaccination coverage was similar ( P ≥ .05) for other outcomes. In subgroup analyses, HPV vaccination also differed depending on the number and type of special health care needs identified. Findings highlight low levels of vaccination overall and missed opportunities to administer recommended vaccines among all youth, including YSHCN.
Obesity and Falls in a Prospective Study of Older Men: The Osteoporotic Fractures in Men Study
Authors: Hooker Elizabeth R. , Shrestha Smriti , Lee Christine G. , Cawthon Peggy M. , Abrahamson Melanie , Ensrud Kris , Stefanick Marcia L. , Dam Thuy-Tien , Marshall Lynn M. , Orwoll Eric S. , Nielson Carrie M. ,   Osteoporotic Fractures in Men (MrOS) Study
Published: July 2016

Objective: The aim of this study is to evaluate fall rates across body mass index (BMI) categories by age group, considering physical performance and comorbidities. Method: In the Osteoporotic Fractures in Men (MrOS) study, 5,834 men aged ≥65 reported falls every 4 months over 4.8 (±0.8) years. Adjusted associations between BMI and an incident fall were tested using mixed-effects models. Results: The fall rate (0.66/man-year overall, 95% confidence interval [CI] = [0.65, 0.67]) was lowest in the youngest, normal weight men (0.44/man-year, 95% CI = [0.41, 0.47]) and greatest in the oldest, highest BMI men (1.47 falls/man-year, 95% CI = [1.22, 1.76]). Obesity was associated with a 24% to 92% increased fall risk in men below 80 ( ptrend ≤ .0001, p for interaction by age = .03). Only adjustment for dynamic balance test altered the BMI–falls association substantially. Discussion: Obesity was independently associated with higher fall rates in men 65 to 80 years old. Narrow walk time, a measure of gait stability, may mediate the association.
Functional Impairment in Children With Externalizing Behavior Disorders: Psychometric Properties of the Weiss Functional Impairment Rating Scale–Parent Report in a German Clinical Sample
Authors: Dose Christina , Hautmann Christopher , Doepfner Manfred
Published: July 2016

Objective: To examine the psychometric properties of a German adaptation of the Weiss Functional Impairment Rating Scale–Parent Report (WFIRS-P) in a clinical sample of children (4-12 years) with externalizing behavior disorders. Method: Data were collected within two clinical trials ( N = 264). Factorial validity, reliability, and divergent validity from symptoms of ADHD and oppositional defiant disorder (ODD) were assessed. Results: Confirmatory factor analyses revealed that a bifactor model consistent with the theoretical assumption of a general construct of impairment (total scale) and additional specific factors (subscales) provided satisfactory data fit. Model-based reliability estimates showed that both the general construct and specific factors accounted for item variance. Internal consistencies were >.70, part–whole corrected item–scale correlations mostly >.30. Correlations between the WFIRS-P Scales and ADHD and ODD symptoms were low to moderate. Conclusion: The results support the factorial validity, reliability, and divergent validity of the WFIRS-P.
When is social media use social interaction? Defining mediated social interaction
Authors: Hall Jeffrey A
Published: July 2016

This investigation explores the question, when is social media use social interaction? The results of three studies indicated that social media use was rarely considered social interaction. After using social media for 5 or 10 minutes, Study 1 ( N = 116) demonstrated that infrequent, directed social media behavior (e.g. chatting, commenting) predicted having a social interaction and feeling related. Study 2 ( N = 197) used event sampling to examine participants’ social interactions with friends ( n = 2388) and found 96.5% of social interactions did not take place on social media. Study 3 ( N = 54) used experience sampling to record participants’ experiences over 5 days ( n = 1332). Social media use and social interaction occasionally co-occurred, but only 2% of social interactions took place through social media. Social interactions through social media were usually talk-focused, one-on-one exchanges with closer relational partners, and rarely undifferentiated, broadcasted, or passively consumed information shared with acquaintances.
Connectivity Node Set Generation Algorithm of Mine WSN Based on the Maximum Distance
Authors: Wang Ke , Xu Donghong
Published: July 2016

Deployment strategy of sensors reflects cost and monitoring capabilities of sensor networks. The strategy not only determines the routine work of the sensor networks but also affects energy consumption, survival time, and quality of service (QoS). In the coal mine, the network generally is long and narrow, and network nodes are equipped with large electrical and mechanical equipment. Those traits have serious impacts on signal transmission of wireless sensor. Therefore, it is important to conduct research on Connectivity Node Set (CNS) of wireless sensor nodes (WSN) in coal mine. Wireless sensor backbone network deployed in a coal mine laneway environment is researched in the paper. We propose a Connectivity Node Set Generation Algorithm of Mine WSN Based on Maximum Distance. The algorithm can maintain stable network communication through deployment of standby nodes on the WSN even when the backbone network nodes malfunction. Meanwhile, it can improve the robustness of WSN in coal mine environment.
Privacy enhancement using selective encryption scheme in data outsourcing
Authors: Nguyen-Vu Long , Park Jungsoo , Park Minho , Jung Souhwan
Published: July 2016

In this article, we introduce a practical scheme that dynamically secures and outsources data on demand as well as propose a corresponding architecture to securely process data in database service provider. We also adopt the application of bring your own device in this scheme as an enhanced security solution. After studying over 1300 database models, we expect this scheme can be applied in production with justifiable result.
A novel multi-objective coverage optimization memetic algorithm for directional sensor networks
Authors: Wang Aimin , Gao Yingnan , Wu Jing , Sun Geng , Jia Wenjuan
Published: July 2016

For the target problem of a directional wireless sensor network, the greedy algorithm can easily fall into the local optimal solution, whereas the genetic algorithm must forecast the lifetime of the upper bound of the network. We propose a novel multi-objective coverage optimization memetic algorithm that encodes the solutions as chromosomes and simulates the biological evolution process in search for a favourable solution to address the aforementioned problems. Experimental results show that the proposed algorithm can prolong the network lifetime more effectively than similar heuristic algorithms in other studies.
Performance analysis of smart digital signage system based on software-defined IoT and invisible image sensor communication
Authors: Hossain Mohammad Arif , Islam Amirul , Le Nam Tuan , Lee Yong Tae , Lee Hyun Woo , Jang Yeong Min
Published: July 2016

Everything in the world is being connected, and things are becoming interactive. The future of the interactive world depends on the future Internet of Things (IoT). Software-defined networking (SDN) technology, a new paradigm in the networking area, can be useful in creating an IoT because it can handle interactivity by controlling physical devices, transmission of data among them, and data acquisition. However, digital signage can be one of the promising technologies in this era of technology that is progressing toward the interactive world, connecting users to the IoT network through device-to-device communication technology. This article illustrates a novel prototype that is mainly focused on a smart digital signage system comprised of software-defined IoT (SD-IoT) and invisible image sensor communication technology. We have proposed an SDN scheme with a view to initiating its flexibility and compatibility for an IoT network-based smart digital signage system. The idea of invisible communication can make the users of the technology trendier to it, and the usage of unused resources such as images and videos can be ensured. In addition, this communication has paved the way for interactivity between the user and digital signage, where the digital signage and the camera of a smartphone can be operated as a transmitter and a receiver, respectively. The proposed scheme might be applicable to real-world applications because SDN has the flexibility to adapt with the alteration of network status without any hardware modifications while displays and smartphones are available everywhere. A performance analysis of this system showed the advantages of an SD-IoT network over an Internet protocol-based IoT network considering a queuing analysis for a dynamic link allocation process in the case of user access to the IoT network.
Directed broadcasting with mobility prediction for vehicular sensor networks
Authors: Cha Si-Ho , Lee Jong-Eon , Ryu Minwoo
Published: July 2016

This article suggests a new directed broadcasting method with mobility prediction of moving vehicles in vehicular sensor networks (VSNs). VSNs can play a critical role to ensure prompt delivery of real-time sensing data and be able to prevent various road dangers. The suggested method is particularly for vehicle safety communication (VSC) on highway roads by using directed broadcasting between vehicles. In VSNs, broadcasting is the most suitable communication mechanism for VSC. The simplest broadcasting mechanism is flooding, which introduces the redundant message retransmission and the broadcast storm problem. It is because all vehicles rebroadcast the messages in flooding. The broadcast storm problem can be addressed with selective flooding schemes which select rebroadcast vehicles to perform rebroadcasting. However, selective flooding schemes cannot promise enough reliability for VSC because of the highly dynamic topology and frequent disconnections of vehicular networks. Fast movement and frequent topology changes cause repeated link breakages and it increases the packet loss rate of vehicular networks. In this article, we propose a mobility prediction-based directed broadcasting (MPDB) protocol to achieve a reliable broadcasting in VSNs. MPDB protocol broadcasts emergent messages only to the rear vehicles on the same road. MPDB protocol consists of two phases: (i) mobility prediction phase and (ii) broadcasting phase. The mobility prediction can be acquired through periodical beaconing. In mobility prediction phase, each vehicle gets its rear vehicle set on the same road through neighbour’s position, inter-vehicle distance, relative speed and moving direction. In broadcast phase, MPDB protocol selects a vehicle having the largest link available time (LAT) values acquired by the mobility prediction as a rebroadcast vehicle among the rear vehicle set acquired in previous phase. By using LAT for broadcasting propagation, MPDB protocol can intensify the reliability of the message dissemination and also prevent the broadcast storm problem in vehicular networks. The simulation results show that MPDB protocol has better performance improvement in terms of average packet rate and packet delay.
The Stener Lesion: Historical Perspective and Evolution of Diagnostic Criteria
Authors: Lark Meghan E. , Maroukis Brianna L. , Chung Kevin C.
Published: July 2016

Background: In 1962, Bertil Stener first described the anatomy and treatment of the displaced ulnar collateral ligament of the metacarpophalangeal joint, later called the Stener lesion. Since Stener’s publication, treatment algorithms for ulnar collateral ligament rupture have aided in preoperative diagnosis, yet the best diagnostic method to assess ligament displacement remains largely undefined. Methods: An extensive literature search was performed to explore the treatment evolution of the Stener lesion and explore how technical development has influenced Stener lesion diagnosis. We also sought to illuminate the life and work of Bertil Stener. Results: Studies evaluating the use of magnetic resonance imaging (MRI) and ultrasound (US) technology have suggested that these modalities have improved Stener lesion diagnosis. Conclusion: Despite the utility of developing MRI and US technology, consensus for one superior diagnostic tool for Stener lesions does not currently exist.
Terror on Trial
Authors: Steinberg Ronen
Published: July 2016

This article discusses the question of accountability after the Terror through a close analysis of the case of Joseph Le Bon, a public official who was put on trial for his role in the repression. This trial has often been seen as reactionary in essence. In contrast, this article argues that it derived from the democratizing impulses of the French Revolution. The Revolution enshrined accountability as a fundamental principle in the new political order. After the Terror, this gave rise to an unpredictable dilemma: how to hold individuals accountable for a mass crime. The article shows how both the case against Le Bon and his defense were shaped by the same democratizing impulses. In this sense, the Thermidorian struggle with justice was continuous with the Revolution. In making its case, the article relies on the concept of transitional justice.
The Culture of Reaction
Authors: Mason Laura
Published: July 2016

Reactionary culture helped shape Thermidor's retreat from the ideologies, social policies, and political practices of the Terror. This article explains how it did so by examining the most popular newspaper of the French Revolution's Year III (1794–95), L'orateur du peuple, and editor Stanislas Fréron's appropriation of revolutionary inventiveness to discredit revolutionary activism. Between Robespierre's defeat in July 1794 and the adoption of a new constitution in late summer 1795, Fréron used radical language to condemn first the Terror and then radical republicanism, progressing from attacks on specific legislators to an assault on social welfare, political militancy, and universal suffrage. Elaborating a right-wing ideology that was neither Catholic nor royalist, L'orateur du peuple illuminates the conservative uses of revolutionary political culture. Fréron and the reactionary polemicists among whom he worked forged a virulent reactionary populism in the Year III whose legacy endures today.
Circuits of Practical Knowledge
Authors: Bond Elizabeth Andrews
Published: July 2016

Letters to the editor were published in the thousands during the 1770s and 1780s, shaping a forum that constituted an eighteenth-century information network. Such letters serve as a powerful touchstone for ideas that circulated among the French reading public, shedding new light on the cultural history of the Enlightenment. Drawing on world history and digital history approaches, this article analyzes a subset of letters that were exchanged and reprinted among provincial papers (affiches) throughout France. By visualizing the exchange of such reprinted letters as a network, it becomes clear that provincial readers did not read their local papers in isolation but instead were connected to a larger community that often included published missives from the surrounding généralité and the capital. The content of such letters communicated an optimism about the possibility of ameliorating daily life through incremental, practical changes, fostering a notion of a practical Enlightenment.
Beautiful Lemons: Adverse Selection in Durable-Goods Markets with Sorting
Authors: Peterson Jonathan R. , Schneider Henry S.
Published: July 2016

We document a basic characteristic of adverse selection in secondhand markets for durable goods: goods with higher observed quality may have more adverse selection and hence lower unobserved quality. We provide a simple theoretical model to demonstrate this result, which is a consequence of the interaction of sorting between drivers over observed quality and adverse selection over unobserved quality. We then offer empirical support using data on secondhand prices and repair rates of used cars from the Consumer Expenditure Survey, and discuss a number of implications for everyday advertising and consumer questions.

Data, as supplemental material, are available at http://dx.doi.org/10.1287/mnsc.2016.2495 .

This paper was accepted by J. Miguel Villas-Boas, marketing.
RPC-Based Coregistration of VHR Imagery for Urban Change Detection
Authors: Jabari Shabnam , Zhang Yun
Published: July 2016

In urban change detection, coregistration between bi-temporal Very High Resolution (VHR) images taken from different viewing angles, especially from high off-nadir angles, is very challenging. The relief displacements of elevated objects in such images usually lead to significant misregistration
that negatively affects the accuracy of change detection. This paper presents a novel solution, called Patch-Wise CoRegistration (PWCR), that can overcome the misregistration problem caused by viewing angle difference and accordingly improve the accuracy of urban change detection. The PWCR
method utilizes a Digital Surface Model (DSM) and the Rational Polynomial Coefficients (RPCs) of the images to find corresponding points in a bi-temporal image set. The corresponding points are then used to generate corresponding patches in the image set. To prove that the PWCR method can
overcome the misregistration problem and help achieving accurate change detection, two change detection criteria are tested and incorporated into a change detection framework. Experiments on four bi-temporal image sets acquired by Ikonos, GeoEye-1, and Worldview-2 satellites from different
viewing angles show that the PWCR method can achieve highly accurate image patch coregistration (up to 80 percent higher than traditional coregistration for elevated objects), so that the change detection framework can produce accurate urban change detection results (over 90 percent).
Measurement of Surface Changes in a Scaled-Down Landslide Model Using High-Speed Stereo Image Sequences
Authors: Feng Tiantian , Mi Huan , Scaioni Marco , Qiao Gang , Lu Ping , Wang Weian , Tong Xiaohua , Li Rongxing
Published: July 2016

Construction of scaled-down landslide models is an important means for landslide study. The objective of this study is to develop an innovative non-contact photogrammetric system to meet the challenge for monitoring the fast surface deformation of a laboratory-simulated landslide, which
can detect pre-failure events and the final failure, provide sectional and overall surface deformation patterns, and generate speed maps during the rapid slope failure. We proposed an event detector based on altered surface features in the slower SLRC (single-lensreflex camera) image sequence
to detect pre-failure events, while a combined analysis tool used the surface velocity fields and deformation areas based on fast HSCS (high-speed stereocamera system) stereo image sequences to reveal fast-changing landslide behavior during the short final failure. The introduced surface change
detector uses the percentage of sliding block areas, percentage of changed features, and average speeds. It successfully detected four pre-failure local collapse events and the final slope failure; the extent of surface changes reached its maximum to accumulate energy 1.5 seconds before the
failure when the average speed of changed features achieved its peak of 0.8 m/s. The developed system achieved a position accuracy of 3.8 mm and a speed accuracy of 0.11 m/s. The analysis result demonstrated a time period of 66 minutes before the failure which is confirmed by significant signals
from both imaging and contact sensors and is important for landslide early warning. A field implementation scheme in western China will be designed and realized in the near future.