bluuebunny/crossref_metadata_2025 huggingface dataset:
Rusli Amran: Pioneer of Local History Research and His Contributions to the History of West Sumatra
Authors: Putri FY Windri Augfensi , Husodo Purwo
Published: October 2024

Rusli Amran, seorang intelektual Minangkabau kelahiran Padang pada 14 September 1922, telah meninggalkan banyak jejak dalam dunia intelektual dan sejarah Indonesia. Karya-karyanya secara tidak langsung dan cukup signifikan membentuk pemahaman masyarakat tentang apa yang pernah terjadi pada masa lampau, terutama di wilayah Sumatra Barat pada era kolonial. Meskipun kontribusi Rusli Amran terhadap bidang sejarah Indonesia tersebut diakui secara luas, tentunya masih diperlukan analisis yang lebih mendalam tentang kerangka intelektual dan metodologi khusus yang digunakannya dalam penyelidikan sejarahnya. Dari empat peristiwa penting yang ada di Sumatera Barat (1981-1997) yakni masuknya VOC ke Kota Padang, Perang Padri, Pembrontakan Batipuh dan Tiga Serangkai: (Tambang Batu Bara Ombilin, Jalan Kereta Api, dan Pelabuhan Teluk Bayur). Rusli Amran menunjukkan bahwa keempat peristiwa sejarah masa kolonial Belanda di Sumatera Barat saling berkaitan. Faktor utamanya adalah masyarakat yang mudah dihasut satu dengan yang lain. Pemerintah kolonial Belanda memanfaatkan faktor utama tersebut, yang membuat masyarakat jadi terpecah, dan para kaum adat mudah dihasut, senang disogok, dan lebih mementingkan kekuasaan. Sedangkan kaum Pidari yang mematahui ajaran Islam sangat membenci hal-hal haram. Inilah yang menyebabkan masyarakat Sumatera Barat mudah terprovokasi. Pemerintah Kolonial Belanda pun tidak tinggal diam dengan memanfaatkan momen tersebut.
Social perceptions of childhood diarrhea in Lubumbashi, Democratic Republic of the Congo: A qualitative study
Authors: Tshika Sidonie Musangu , Kayiba Gertrude Bukasa , Luboya Oscar Numbi
Published: October 2024

Introduction: Infantile diarrhea remains a public health problem in the Democratic Republic of the Congo, where infant mortality linked to this disease remains high despite the proven efficacy of oral rehydration therapy. This study aims to understand the social perceptions of childhood diarrhea among mothers in Lubumbashi, by examining how they diagnose and treat the disease through both popular and biomedical representations.Material and methods: The study was conducted in Lubumbashi, the capital of Haut-Katanga in the DRC, utilizing a qualitative methodology that involved semi-structured interviews with 32 randomly chosen mothers. Selection criteria encompassed the number of children, educational level, religion, and age range (18 to 60). Information was gathered through documents and interviews conducted in Swahili, subsequently translated into French, and analyzed utilizing Jean-Blaise Grize’s ‘natural logic’ to grasp social representations.Results: The study revealed that the majority of mothers associated diarrhea with physical signs such as dehydration, watery stools, depressed fontanel, and sunken eyes. Several mothers attributed the diarrhea to cultural causes, such as the consumption of certain foods by pregnant women (e.g. “kabambale”) or the practice of breastfeeding by pregnant mothers. Local diseases such as “lukunga” and “kilonda ntumbo” are considered to be specific forms of diarrhea in popular culture. Treatments include traditional remedies such as ash applications and sitz baths.Conclusion: Perceptions of childhood diarrhea in Lubumbashi reflect a tension between cultural beliefs and biomedical knowledge, where rehydration is often neglected. The study recommends raising community awareness of the effectiveness of ORT while respecting local beliefs.
TÉCNICAS DE HIGIENE Y DE PRESERVACIÓN DE PRÓTESIS DENTALES EN PACIENTES EDÉNTULOS TOTALES Y EDÉNTULOS PARCIALES
Authors: Mejia Osorio Heylen daniela , Ibagón Soto Estefania , Yunda Guaranga Tatiana , Contreras Rengifo Adolfo , García Zapata Lina María
Published: October 2024

Antecedentes: El 31.62% de la población colombiana usa algún tipo de prótesis dental. El uso de una prótesis dental requiere del control periodico del odontólogo y el cuidado diario de los pacientes para mantener la salud bucal y prolongar la vida útil de las prótesis. La higiene bucal debe incorporar las prácticas de cuidado y almacenamiento de prótesis dentales, ya que estas últimas son una opción de tratamiento muy frecuente.
La deficiencia Fallas en la higiene y en el almacenamiento (preservación) de las prótesis dentales pueden afectar los tejidos orales, los dientes y deteriorar los materiales protésicos.
Objetivo: determinar los conocimientos y prácticas de higiene y almacenamiento de las prótesis bucodentales en 38 pacientes adultos que asisten a las clínicas odontológicas de una institución Universitaria en Cali- 2023.
The Bright and Dark Sides of Sports Interpreting in Iraq: Football Interpreting as an Example
Authors: Yacob Al-Dirawi Afaneen Abdul-Wahid , Khalaf Al-Taie Ruqaya Sabeeh , Sultan Al-Maryani Jasim Khalifah
Published: October 2024

With the rapid increase in international matches, such as the Olympic Games, World Cup by FIFA, Arab or Gulf Cup events the demand for interpreting becomes very necessary, as through this activity players can connect with viewers around the world, this is on the one hand, and on the other, through which they can instantly obtain their instructions.  After the war in 2003, the participation of Iraqi athletes in international competitions and the recruitment of foreign coaches flourish. This new situation urges policy designers to strategically plan to offer qualified interpreters to ensure ideal communication between the players and their coaches and between them and the international audience. The status quo, however, is very frustrating: the number of Iraqi qualified interpreters can relatively be visible (for the ordinary observers) as there are no specialized academic or non-academic institutions that offer the requirements. This lack has opened the door for non-professional interpreters to carry the task leading not only to fragmented communication but also to deform the perception of this profession. This study sheds light on this particular area. It solely adopts the participant-oriented method offered by Saldanha and O’brein (2013). The research instrument is a carefully-designed questionnaire which is presented to a sample of thirty professional interpreters. The study findings emphasize that the status quo of sports interpreting in Iraq is discouraging because of some obstacles, such as the absence of specialized interpreting training facilities and monitoring institutions.
Translation and Diplomacy : The Role of Translators in International Relations
Authors: Zouba'a Ayad Mahmood
Published: October 2024

This study sheds lights on the role of  translators in international relations . It aims to study the translation strategies used in translating the diplomatic texts , to identify the difficulties faced by translators in translating the texts in the diplomatic field . It hypothesizes that the translators have a limit knowledge of such terms used in diplomatic context . In the present study , four samples contained diplomatic terms were taken and rendered by translators adopted Vinay and Darblent strategies (1995) of direct translation and oblique translation to know how the meaning is conveyed from the source text into the target text.
A COGNITIVE STUDY OF DRINK EXPRESSIONS IN ENGLISH PROVERBS
Authors: Namiq Ma'aly Sattar , Ali Hasan Shaban
Published: October 2024

Conceptual Metaphor Theory represents the output of a cognitive process by which readers can understand one domain in terms of another. This study aims to investigate the use of drink proverbs in English from a cognitive point of view and investigate the role of metaphor in communication as an unconscious process in everyday life. Also, it aims to identify metaphor as a systematic process that does not occur randomly. It is considered as a problematic task for learners to understand, interpret, and render the exact conceptual meaning of English proverbs. The procedures of this study are as follows: Presenting a theoretical framework of cognitive linguistics and adopting the model of the conceptual metaphor theory which is Lakoff and Johnson's “Metaphor We Live by” (2003) to analyze proverbs of drink in English. Another two models are used to support the first one which are  Newman's (1997) “Eating and Drinking as a Source of Metaphor in English” and Quirk et al (1985) “A Comprehensives Grammar of the English Language”.  The study hypothesizes that the source and target domains in conceptual metaphors have a crucial role in understanding the meaning of drink proverbs in English. Concerning the levels of analysis, the present study deals with the semantic and grammatical levels. The data are collected from dictionaries that are associated with drink proverbs. Six samples are chosen for the analysis. In each sample, more than five items have been analyzed metaphorically and grammatically.  The present study concluded that conceptual metaphors do not occur randomly and they are unconscious processes through conversations.
Time-Dependent Reachable Domain and Its Application to Impulsive Orbital Pursuit–Evasion Analysis
Authors: Zhang Sai , Yang Zhen , Luo Ya-Zhong
Published: October 2024

Orbital pursuit–evasion (OPE) has garnered significant attention due to its potential applications in space rendezvous and proximity operations. Conventional methods using differential games do not fully address the impulsive OPE problem, which involves a discontinuous differential system. This paper presents the concept of a time-dependent reachable domain (TDRD) for analyzing the impulsive OPE problem. The range and time constraints for determining the TDRD are first given. These constraints can be solved to identify two different TDRDs: the RD at a given time and the RD over a duration. The numerical results obtained from the proposed method exhibit good agreement with those from Monte Carlo simulations, validating the practicality of using TDRDs for OPE analysis. Four different qualitatively OPE outcomes are defined based on the geometrical relationship between the spacecraft’s TDRDs. A series of application cases are comprehensively examined to prove that TDRDs directly predict the sufficient conditions leading to a specific OPE outcome. These findings demonstrate that the TDRD concept is a potent and efficacious instrument for studying the impulsive OPE problem.
Onboard Burn Targeting and Guidance of NASA Human Flight Vehicles
Authors: Goodman John L.
Published: October 2024

The mission requirements of crewed space vehicles flown by NASA drove the development of new techniques for burn targeting and guidance for ascent, rendezvous, lunar landing, and deorbit. The Saturn V Iterative Guidance Mode used an approximately optimal steering law that could adjust the trajectory to compensate for performance issues while meeting trajectory constraints at propulsion-system cutoff. Hypersurface targeting provided constraints for the Saturn V Trans-Lunar Injection burn. E Guidance, in quadratic- and linear-acceleration forms, provided closed-loop descent and ascent guidance for the Apollo Lunar Module. The Space Shuttle’s Powered Explicit Guidance algorithm was more flexible than Apollo-era guidance algorithms, and it had better convergence characteristics, enabling it to support challenging abort profiles. The Space Launch System has built on the heritage of the Space Shuttle’s guidance algorithm. The Orion spacecraft’s Two-Level Targeter enables onboard, autonomous targeting of an entire mission profile subject to three-body dynamics in cislunar space. Orion uses Shuttle-derived guidance as the basis for an orbit-guidance package with more capability than guidance algorithms of previous vehicles.
Development of Air–Ti Gas-Surface Reaction Mechanisms and Rate Calculations
Authors: Yamada Takahiro , Flora Giacomo , Bisek Nicholas J.
Published: October 2024

Gas-surface reaction mechanisms and rates were developed for an air–titanium surface to support finite-rate catalytic surface reaction models used in computational fluid dynamics. For the surface dissociation/recombination reactions, a two-step reaction method was applied based on the assumption that two atoms must be positioned in adjacent cells to recombine. Transition state theory was used to calculate the surface reactions for adsorbed diatomic molecules to dissociate to the adjacent unit cell or atoms located in the adjacent cells to recombine into diatomic molecules. For the second step, atoms located in the adjacent cells are allowed to further dissociate to another cell (total separation), or totally separated atoms recombine into the adjacent cells. A stochastic gas-surface kinetics simulation code, STOKIN, was developed to simulate gas-surface reactions and to calculate the equilibrium constants of second molecular dissociation [Formula: see text] recombination processes. Thermodynamic properties of the adsorbates (enthalpies, entropies, and heat capacities) were calculated using density functional theory along with statistical mechanics assuming no rotational and translational contributions to the entropies and heat capacities due to the adsorbates’ inability to freely move or rotate on the surface.
Forward and Inverse Modeling of Depth-of-Field Effects in Background-Oriented Schlieren
Authors: Molnar Joseph P. , LaLonde Elijah J. , Combs Christopher S. , Léon Olivier , Donjat David , Grauer Samuel J.
Published: October 2024

This paper reports a novel cone-ray model of background-oriented schlieren (BOS) imaging that accounts for depth-of-field effects. Reconstructions of the density field performed with this model are far more robust to the blur associated with a finite aperture than conventional reconstructions, which presume a thin-ray pinhole camera. Our model is characterized and validated using forward evaluations of simulated buoyancy-driven flow and both simulated and experimental BOS measurements of hypersonic flow over a sphere. Moreover, the model is embedded in a neural reconstruction algorithm, which is demonstrated with a total variation penalty and the compressible Euler equations. Our cone-ray technique dramatically improves the accuracy of BOS reconstructions: the shock interface is well-resolved in all our tests, irrespective of the camera’s aperture setting, which spans f-numbers from 22 down to 4.
Pendampingan Petani Kelompok Karang Taruna Desa Langsat Permai Kecamatan Bungaraya dalam Peningkatan Produksi Padi Melalui Sistem Tanam Benih Langsung (TABELA)
Authors: Hapsoh Hapsoh , Wawan Wawan , Dini Isna Rahma , Nazarudin Nazarudin , Mardiana Mardiana , Mandataris Mandataris
Published: October 2024

Indeks panen (IP) padi di Desa Langsat Permai masih belum mencapai IP 300 akibat pola sistem budidaya tanaman padi yang dilakukan masih konvensional (tanam pindah/TAPIN) sehingga diperlukan waktu yang cukup lama dari masa pindah tanam sampai akhirnya panen dan dilakukan penanaman lagi. Oleh karena itu, sistem budidaya padi dengan sistem tanam benih langsung (TABELA) dapat menjadi salah satu solusi yang dapat membantu petani dalam meningkatkan indeks panen (IP) maupun produksi tanaman padi. Pendampingan ini merupakan kelanjutan dari pendampingan pada tahun sebelumnya (2023). Pada tahun 2023 telah terjadi peningkatan pengetahuan dan keterampilan petani dalam budidaya dengan sistem Tabela. Hal ini ditunjukkan dari meningkatnya minat petani untuk melakukan budidaya padi dengan sistem Tabela. Namun, alat penanaman sistem Tabela (Atabel) hanya dapat digunakan dalam waktu singkat. Oleh karena itu, pada tahun 2024 ini telah dilakukan pendampingan dalam pembuatan alat Tabela yang lebih tahan lama dan pendampingan melalui pembuatan demonstrasi plot budidaya padi dengan sistem Tabela dengan menerapkan inovasi pupuk hayati konsorsium bakteri selulolitik hasil riset tim pengabdian yang diperkaya bahan organik seperti Mucuna bracteata untuk mendukung pertumbuhan dan produksi padi dengan sistem Tabela sehingga pada akhirnya mewujudkan pertanian berkelanjutan di Desa Langsat Permai. Hasil pengabdian menunjukkan bahwa terjadi peningkatan keterampilan petani dalam membuat desai alat Tabela maupun pembuatan pupuk organik hayati pada budidaya tanaman padi.
Pencegahan Demam Berdarah Dengue dengan Edukasi dan Pembuatan Abate Alami dari Biji Pepaya Dan Serbuk Daun Ketapang di Desa Pandak Daun Kecamatan Karang Intan
Authors: Nurmansyah Dian , Afra Fairuz Yaumil , Khairunnisa Khairunnisa
Published: October 2024

Demam Berdarah Dengue (DBD) adalah masalah kesehatan global yang memengaruhi negara-negara tropis seperti Indonesia. Penelitian ini bertujuan untuk meningkatkan pengetahuan masyarakat tentang penyakit DBD dan pencegahannya melalui edukasi dan penggunaan biolarvasida alami dari biji pepaya dan daun ketapang. Kegiatan ini dilakukan di Desa Pandak Daun, dengan responden yang diberikan kuesioner pre-test untuk mengukur pengetahuan awal mereka. Setelah itu, diberikan edukasi menggunakan media visual dan flyer, diikuti dengan kuesioner post-test untuk mengukur peningkatan pengetahuan. Selain itu, dilakukan demonstrasi pembuatan larvasida alami dari bahan-bahan tersebut. Hasil analisis data menunjukkan adanya peningkatan pengetahuan tentang penyakit DBD sebesar 6,2% dan peningkatan pengetahuan pencegahan sebesar 5,9%. Uji statistik menunjukkan perbedaan signifikan (p < 0,05) antara tingkat pengetahuan sebelum dan sesudah edukasi. Kesimpulan yang didapat adalah edukasi yang diberikan secara efektif meningkatkan pengetahuan masyarakat tentang DBD dan pencegahannya, serta penggunaan biolarvasida alami menawarkan alternatif ramah lingkungan dalam mengendalikan penyebaran nyamuk Aedes aegypti
Meningkatkan Literasi Keuangan Syariah pada Siswa Sekolah Menengah Atas (SMA) Negeri 2 Kuala Kabupaten Nagan Raya
Authors: Muliza Muliza , Zahra Indah , Selviani Rika Dara
Published: October 2024

Literasi keuangan syariah merupakan keterampilan esensial yang harus dimiliki oleh generasi muda, terutama di Provinsi Aceh yang menerapkan syariat Islam secara komprehensif. Penelitian ini bertujuan untuk meningkatkan literasi keuangan syariah pada siswa SMA Negeri 2 Kuala melalui program pengabdian masyarakat yang melibatkan seminar, workshop, simulasi, dan diskusi kelompok. Sebanyak 50 siswa berpartisipasi dalam program ini, yang berlangsung selama 2 Hari. Hasil penelitian menunjukkan peningkatan signifikan dalam pemahaman siswa tentang prinsip-prinsip dasar keuangan syariah, pengetahuan tentang produk keuangan syariah, serta sikap dan perilaku siswa dalam mengelola keuangan pribadi sesuai dengan prinsip-prinsip syariah. Sebelum program, hanya 30% siswa yang memahami dasar-dasar keuangan syariah, sementara setelah program, angka ini meningkat menjadi 85%. Selain itu, penerapan prinsip-prinsip syariah dalam kehidupan sehari-hari juga meningkat, dengan 60% siswa mulai menggunakan produk keuangan syariah. Hasil ini menunjukkan bahwa program pengabdian masyarakat ini efektif dalam meningkatkan literasi keuangan syariah dan memiliki dampak positif jangka panjang yang berkelanjutan. Program ini diharapkan dapat menjadi model yang dapat diterapkan di sekolah-sekolah lain di Aceh dan Indonesia dalam rangka meningkatkan literasi keuangan syariah di kalangan generasi muda.
Pelatihan Mendeley Desktop Bagi Mahasiswa dalam Penulisan Artikel Penelitian
Authors: Isyanto Agus Yuniawan , Kurnia Rian , Andrie Benidzar M. , Amalia Lidya Nur
Published: October 2024

Mahasiswa Program Studi Agribisnis Fakultas Pertanian Universitas Galuh diwajibkan membuat artikel jurnal penelitian yang diambil dari skripsi, dan artikel jurnal penelitian tersebut merupakan salah satu syarat pelaksanaan sidang skripsi. Dalam penulisan skripsi dan artikel jurnal penelitian tersebut diperlukan manajer referensi yang memudahkan mahasiswa dalam pengelolaan referensi, salah satunya adalah Mendeley. Tujuan dilaksanakannya kegiatan pengabdian kepada masyarakat berupa pelatihan Mendeley desktop ini adalah agar mahasiswa mampu menggunakan aplikasi manajer referensi Mendeley dalam pembuatan skripsi dan artikel jurnal penelitian sebagai salah satu syarat sidang pada program Studi Agribisnis Fakultas Pertanian Universitas Galuh. Kegiatan pengabdian kepada masyarakat ini dilakukan dengan tahapan sebagai berikut: (1) Pre test, (2) Pelatihan Mendeley desktop, dan (3) Pre test. Hasil kegiatan PkM menunjukan bahwa pelatihan Mendeley desktop berdampak terhadap peningkatan pengetahuan dan keterampilan peserta dalam menggunakan aplikasi manajer referensi Mendeley. Terdapat perbedaan yang signifikan dalam hal pengetahuan dan keterampilan peserta tentang Mendeley desktop, sebelum dan sesudah mengikuti pelatihan Mendeley desktop yang menunjukan adanya peningkatan pengetahuan dan keterampilan peserta tentang Mendeley desktop setelah mengikuti pelatihan.
APRESENTAÇÃO: JUSTIÇA CLIMÁTICA, ORGANIZAÇÕES INTERNACIONAIS E COOPERAÇÃO: DESAFIOS PARA A AGENDA 2030 NO BRASIL
Authors: Vitale Denise , Rached Danielle Hanna
Published: October 2024

O presente artigo apresenta o dossiê Justiça Climática, Organizações Internacionais e Cooperação: desafios para a agenda 2030 no Brasil, que busca discutir aspectos diversos e complementares da agenda climática e dos compromissos internacionais brasileiros. O dossiê tem como foco as demandas por justiça, que se ampliam e se agravam da conhecida questão social para a urgente questão climática. O aquecimento global e a intensificação dos eventos extremos causados pelas alterações climáticas tornaram-se uma realidade e é preciso compreender sua complexa dimensão para pensar possibilidades de mitigar e adaptar as sociedades a essa nova era. O dossiê oferece um amplo panorama do tema, com abordagem crítica e interdisciplinar, considerando a multiplicidade de atores e níveis envolvidos.
Caracterização clínica-epidemiológica de pacientes com cirrose hepática atendidos em um serviço de referência na Amazônia
Authors: Santos Izabelly Biase Damasceno dos , Sampaio Luís Filipe de Castro , Farias Larissa dos Reis , Sampaio Pedro Henrique de Castro , Cruz Fernando Costa da , Silva Felipe Jose Silva e , Passos Ellen Sabrinna dos Remédios , Damasceno Rodrigo Janderson Amaral , Ribeiro Elenilda da Conceição , Pereira Lizomar de Jesus Maues
Published: October 2024

Objetivo: Caracterizar pacientes com cirrose e suas complicações. Métodos: Estudo transversal de pacientes com cirrose hepática atendidos em um ambulatório de Hepatologia da Fundação Santa Casa de Misericórdia do Pará, realizado com aplicação de questionários. Os dados foram analisados utilizando o Microsoft® Excel e o Jamovi. Resultados: Estudo com 70 pacientes com cirrose hepática revelou prevalência discreta em mulheres. O etilismo e o tabagismo foram os hábitos mais encontrados. Metade foi diagnosticada por meio de exames complementares. As principais causas foram Doença Hepática Alcoólica (DHA) e Doença Hepática Gordurosa Não Alcoólica (DHGNA)/Esteatohepatite Não Alcoólica (EHNA), seguida de hepatite C e outras. Ascite, hemorragia digestiva alta e hipertensão portal foram as complicações mais comuns. Destaque para DHGNA/EHNA como causa emergente associada a cirrose hepática e as complicações, como ascite e hipertensão portal. Conclusão: Predominância feminina, idade média 60,5 anos. A ascite foi a complicação mais relatada, relacionada à hipertensão portal. É importante a implantação de medidas de saúde pública e educação em saúde, para identificar casos de DHGNA/EHNA e DHA, com foco na prevenção da cirrose hepática visando a redução de complicações e melhoria dos desfechos clínicos.
MicroRNA expression signature in gastrointestinal stromal tumour & their molecular & histological features
Authors: Ghani Abdul , Singh Harvinder , Kumar Hemanth , Vaiphei Kim
Published: October 2024

Background & objectives

In gastrointestinal stromal tumour (GIST), not only genetic abnormalities are responsible for adverse clinical events, but epigenetic modifications also play a crucial role. MicroRNA (miRNA) dysregulation plays a significant role in carcinogenesis as miRNAs serve as natural silencer for their targets. Our study aimed to explore the miRNAs expression and its association with molecular and histopathological characteristics of GIST.

Methods

Fifty GIST samples, including 45 formalin fixed paraffin embedded (FFPE) and fresh tissues were included. Peripheral non-tumour tissues were used as controls. All the cases were confirmed using immunohistochemistry. RNA was extracted using miRNA-specific kit, and the expression was performed using RT-qPCR. The data were evaluated using AriaMx software version 1.5 (Agilent, US). MiRNAs expression was analyzed by using the relative quantification method (ΔΔCT).

Results

miR-221, miR-222, miR-494 and miR-34a showed significant down-regulation in tumours relative to non-tumour tissues. The expression levels of these miRNAs were significantly down-regulated in c-KIT (proto-oncogene encoding the tyrosine kinase transmembrane receptor)-positive tumours compared to c-KIT-negative. Further analysis revealed that reduced expression was associated with spindle subtypes and gastric localization. However, there was no significant correlation with other histological features. Additionally, miR-221/222, and miR-494 were down-regulated in most of the KIT exon 11 mutant subtypes, while miRNA-34a was associated with platelet derived growth factor receptor alpha (PDGFRA) mutations.

Interpretation & conclusions

The present study showed that the down-regulation of these miRNAs may help better molecular classification and characterization of GISTs. Our results offer new insight into the association between miRNAs and histological features, enabling a more thorough understanding of GISTs at the molecular level.
Primary Partial Shoulder Replacement: 2024 Supplementary Report
Authors:   Australian Orthopaedic Association National Joint Replacement Registry, Gill David RJ , Lewis Peter L ,   Australian Orthopaedic Association National Joint Replacement Registry,   University of Adelaide Medical School, McAuliffe Michael J ,   Australian Orthopaedic Association National Joint Replacement Registry,   Queensland University of Technology, McDougall Catherine ,   Australian Orthopaedic Association National Joint Replacement Registry,   University of Queensland Medical School, Stoney James D ,   Australian Orthopaedic Association National Joint Replacement Registry, Vertullo Christopher J ,   Australian Orthopaedic Association National Joint Replacement Registry,   Menzies Health Institute, Griffith University,   Knee Research Australia, Wall Christopher J ,   Australian Orthopaedic Association National Joint Replacement Registry,   University of Queensland Rural Clinical School, Corfield Sophia ,   Australian Orthopaedic Association National Joint Replacement Registry, Du Peiyao ,   South Australian Health and Medical Research Institute, Holder Carl ,   South Australian Health and Medical Research Institute, Harries Dylan ,   South Australian Health and Medical Research Institute, Edwards Suzanne ,   South Australian Health and Medical Research Institute, Zu Qunyan ,   South Australian Health and Medical Research Institute, Lorimer Michelle F ,   South Australian Health and Medical Research Institute, Cashman Kara ,   South Australian Health and Medical Research Institute, Smith Paul N ,   Australian Orthopaedic Association National Joint Replacement Registry,   Australian National University Medical School
Published: October 2024

This supplementary report provides detailed information on partial shoulder replacement. The Partial Shoulder Arthroplasty Report is one of 14 supplementary reports to complete the AOANJRR Annual Report for 2024. Information on the background, purpose, aims, benefits and governance of the Registry can be found in the Introductory chapter of the 2024 Hip, Knee and Shoulder Arthroplasty Annual Report. The Registry data quality processes including data collection, validation and outcomes assessment, are provided in detail in the Data Quality section of the introductory chapter of the 2024 Hip, Knee and Shoulder Arthroplasty Annual Report: https://aoanjrr.sahmri.com/annual-reports-2024.
Determinan Pajanan Pestisida Terhadap Kadar Haemoglobin Wanita Usia Subur (WUS) di Kecamatan Dempo Selatan Pagar Alam
Authors: Purba Imelda , Ningrum Rafika Oktiva , Saci Muhammad Amin Arigo
Published: October 2024

Women of childbearing age are a group that plays an important role in the agricultural sector not only in Indonesia but also in other agricultural countries around the world. The types of agricultural activities undertaken by WUS are sometimes the same as those of men, even those that allow contact with pesticides. Women of childbearing age in Pagaralam are at risk of experiencing health effects such as anemia, due to their exposure to Organophosphates. It is necessary to conduct research aimed at analyzing the determinants of pesticide exposure to the haemoglobin level in WUS as a basis for recommendations for efforts to prevent and overcome the effects of pesticide exposure. The design of this study was observational with a cross sectional study approach. The study population was women of childbearing age who were exposed to pesticides in the South Dempo District of Pagaralam, with a sample size of 120 WUS. Sampling using cluster sampling technique. Data collection was carried out through interviews using a questionnaire, observation using a checklist, measurement of body weight using a weight scale, height using a microtoise, and Hb levels using the Easy Touch GCHB tool. Data analysis of the results of the study was carried out univariately, and bivariate using the Chi- Square.The results of    bivariate analysis of variables show that were significant with the haemoglobin level in women of childbearing age in South Dempo District were tenure, long time laundry spraying  and length of time preparing pesticide. While variables that are not associated with haemoglobin levels are  length of spraying, length of time mixed,  frequency of spraying, and use of PPE. It is recommended that women of childbearing age reduce the length of time washing clothes spraying and the length of time preparing pesticides through good time management.  
Keywords : Haemoglobin level, pesticide exposure, woman of childbearing age
Recherche-action en partenariat et ressources végétales mobilisables pour la production de lombricompost dans les Hautes Terres de Madagascar
Authors: Rakotobe Rovanirina , Razafindrakoto Malalatiana , Ravonjiarison Nasandratra , Blanchart Éric , Andriamifidy Tantely Razafimbelo , Bernard Laetitia , Raminoarison Manoa , Rakotomalala Heriniaina Hobiarivelo , Ratsiatosika Onja , Autfray Patrice
Published: October 2024

Description du sujet. Au niveau d’une commune péri-urbaine à Madagascar, un dispositif de recherche-action en partenariat a pour objectif d’améliorer l’offre en fertilisation organique par le lombricompostage. Objectifs. Un inventaire des ressources végétales potentiellement mobilisables en lombricompostage a été premièrement effectué au cours des trois saisons agricoles. Méthode. Une capitalisation des savoirs locaux a été effectuée en associant enquêtes individuelles et ateliers collectifs regroupant 42 agriculteurs et 10 animateurs. Résultats. Soixante-trois espèces ont pu être identifiées avec leurs noms scientifiques et vernaculaires. Leurs utilisations habituelles ont été précisées. Ces ressources ont été regroupées en des entités contrastées : arbres, arbustes et plantes grasses, herbacées des jachères et friches, adventices et résidus de culture. Les résidus de riz, pailles et balles sont mobilisables hors saison des pluies (mai à novembre), alors que les adventices et les espèces annuelles des jachères et friches sont principalement mobilisables pendant la saison des pluies (décembre à avril). L’atelier de capitalisation a permis de recenser les savoirs des agriculteurs sur 27 des 63 espèces. Les six ressources végétales principales identifiées par les agriculteurs comme potentiellement mobilisables et propices au lombricompostage comprennent trois arbustes, les pailles de riz, les pailles de graminées de jachère et friche et les résidus de bananier. Conclusions. Ce diagnostic inséré dans une première boucle de recherche-action en partenariat a permis de déterminer la disponibilité de ressources végétales pour le lombricompostage et d’associer savoirs locaux et connaissances scientifiques dans le cadre d’un apprentissage croisé.
Coleseed oil in compound feeds for broilers
Authors: ЗАРУДНЫЙ В.
Published: October 2024

Опытным путем доказано, что в рационы для мясной птицы целесообразно включать масло из семян сурепицы. При его вводе в кормосмесь повышается интенсивность роста бройлеров, сокращаются затраты корма и улучшается качество получаемой продукции.
Geopolitical competition of great powers in the Arctic
Authors: Karsanova E. S.
Published: October 2024

The article examines the complex issues of Arctic security arising from changing geopolitical realities; explores the new Cold War atmosphere in the region mixed with melting ice, which affects military planning and opens new economic opportunities and access to natural resources. Particular attention is paid to the reasons for the competition of great powers for primacy in the Arctic. It is noted that in recent years, the region has begun to shift from the principles of international cooperation and has quickly transformed into an arena of great power rivalry. The military presence has increased as well as the competing economic investments and political activity from significant political actors: Russia, China, and the United States of America. Now that all the great powers are investing in the Arctic, the concept of peace and cooperation is giving way to the concept of security and deterrence. To examine these factors, thе article uses a typical neorealist view of international relations, arguing that the driving force behind the rapid growth of the Arctic race is not the region itself, but the transforming structure of the international relations, which tends to effectively reproduce the causes of global competition. It the author’s view, peaceful rivalry in the Arctic may not last long, given the lack of effective institutions to address security issues in the region and the fact that changes in the global balance of power also affect local disputes and grievances.
Impact of digitalisation on the structure of youth political leadership
Authors: Sudorgin O. A. , Agafonov A. V.
Published: October 2024

At the present stage, youth political leadership is in the focus of attention of researchers due to the fact that youth policy is an important part of public policy. The concept of the youth political leadership is relatively new and interdisciplinary, integrating politological, sociological, psychopolitical, and managerial approaches. To analyse the phenomenon, the systematisation of scientific approaches to the study of political leadership is conducted, 6 stages of the development of scientific thought from the second half of the XIX century to the beginning of the XXI one are highlighted. The classical and modern theories of leadership are considered. The article substantiates the mediation of methodological approaches to the political leadership by the historical and political context and the level of development of the political culture of society. They are the basis for studying the structure of the phenomenon in question. It is proved that under the influence of digitalisation as the most important aspect of reality, as an attribute of politics and the socio-economic sphere, the structure of the youth political leadership is undergoing a change. Digitalisation makes adjustments to the existing scientific and methodological basis of the political leadership. The analysis of available leadership concepts has shown a movement from its personal aspect to the socio-interactive one, however, in the context of digital transformation, it is necessary to introduce a digital component of leadership. Based on empirical data, the modern structure of the youth political leadership is derived, consisting of three components: personal, socio-interactive, and digital.
Sm(II)-catalyzed reduction of dinitrogen, nitrite and nitrate to ammonia or urea
Authors: Bhimpuria Rohan , Thapper Anders , Borbas K. Eszter
Published: October 2024

Industrial dinitrogen reduction to ammonia in the Haber-Bosch synthesis is essential for the production of fertilizers, and consequently, of food. This process accounts for up to 2% of global energy use. Methods wherein the energy for nitrogen activation is supplied by light could provide more sustainable alternatives to existing ones. The first transition-metal free molecular photocatalyst for the reduction of dinitrogen to ammonia is reported. The catalyst is based on Earth-abundant Sm. The reaction proceeds at ambient pressure and temperature with high turnover numbers (up to 70) with visible light irradiation in aqueous solvent mixtures and even pure water, and uses an environmentally benign non-metallic sacrificial reductant. Nitrite and nitrate were also efficiently reduced to ammonia. The first photocatalytic co-reduction of nitrite and bicarbonate to urea using a Sm-based photocatalyst was achieved.
Functionalized Cyclic Olefin Copolymers: Chemoselective Polymerization of Cyclopropane-Containing Norbornadiene Dimer using Titanium Catalyst and Post-Polymerization Modification
Authors: Iwata Yusuke , Shiono Takeshi , Matsuoka Shin-ichi
Published: October 2024

The synthesis of functionalized polyolefins is important for turning their properties and expanding their application range. However, the copolymerization of olefins with polar monomers using early transition-metal catalysts remains a formidable challenge. Here, we demonstrate a synthesis strategy through the Ti-catalyzed addition polymerization of a cyclopropane-containing norbornadiene dimer (1) followed by post-polymerization modification (PPM). The polymerization of 1 using a constrained-geometry Ti catalyst afforded poly1 with narrow molecular weight distributions (Đ < 1.3), wherein the molecular weight linearly increased against the monomer conversion. Additionally, the copolymerization of 1 with 1-octene proceeded rapidly, and 1 was consumed faster than 1-octene to form gradient copolymers. Further, the 13C nuclear magnetic resonance (NMR) spectroscopies indicated the 2,3-addition structure of poly1 and no side reaction at the cyclopropane moiety. The polymerizations were highly controlled and chemoselective owing to the lack of cyclopropane coordination to the active polymerization Ti species. The PPM of poly(1-co-1-octene) via the protic acid-catalyzed ring-opening reaction of the cyclopropane introduced aromatic, acyloxyl, and alkoxy groups in high incorporation ratios without cross-linking reactions. Thus, this work demonstrates a promising procedure for the modification of cyclic olefin copolymers using specific cyclopropane reactivity.
Advancements in loop cyclisation approaches for enhanced pep1de therapeutics for targeting protein-protein interactions
Authors: Lombardi Lucia , Granger Luke A. , Shattock Robin J. , Williams Daryl R.
Published: October 2024

Protein-protein interactions (PPIs) are pivotal in regulating cellular functions and life processes, making them promising therapeutic targets in modern medicine. Despite their potential, developing PPI inhibitors poses significant challenges due to their large and shallow interfaces that complicate ligand binding. This study focuses on mimicking peptide loops as a strategy for PPI inhibition, utilising synthetic peptide loops for replicating critical binding regions. This current work explores turn-inducing elements and highlights the importance of proline in promoting favourable conformations for lactamisation, yielding high-purity cyclic peptides. Notably, our one-pot method offers enhanced versatility and represents a robust strategy for efficient and selective macrolactamisation, expanding the scope of peptide synthesis methodologies. This approach, validated through the synthesis of AAV capsid-derived loops, offers a robust platform for developing peptide-based therapeutics and highlights the potential of peptide macrocycles in overcoming PPI drug discovery challenges and advancing new therapeutics development.
In-silico Analysis of Vitamin D Interactions with Aging Proteins: Docking, Molecular Dynamics, and Solvation-Free Energy Studies
Authors: Tuntufye Edna , Paul Lucas , Raymond Jofrey , Chacha Musa , Paluch Andrew , Shadrack Daniel
Published: October 2024

Aging is a natural process that is also influenced by some factors like food someone eats, lifestyle decisions, and impacts on general health. Despite the recognized role of nutrition in modulating the molecular and cellular mechanisms underlying aging, there is a lack of comprehensive exploration into potential interventions that can effectively mitigate these effects. In this study, we investigated the potential anti-aging properties of vitamin D by examining its interactions with key molecular targets involved in aging-related pathways. By using molecular docking and dynamics techniques, we evaluate the interactions and stability of vitamin D2 and D3 with key proteins involved in aging pathways, such as SIRT1, mTOR, AMPK, Klotho, AhR, and MAPK. Our results reveal promising binding affinities between vitamin D and SIRT1 forms, with energy values of -48.33 kJ/mol and -45.94 kJ/mol for vitamin D2 and D3, respectively, in aqueous environments. Moreover, molecular dynamics simulations reveal that the vitamin D3-SIRT1 complex exhibits greater stability compared to the vitamin D2-SIRT1 complex. The study calculated the solvation-free energy to compare the solubility of vitamins D2 and D3 in water and various organic solvents. Despite their strong interactions with water, both vitamins exhibit low solubility, primarily due to the high energy cost associated with cavity formation in the aqueous environment. Compared to other solvents, water demonstrated particularly low solubility for both vitamins. This suggests that vitamins D2 and D3 prefer binding to aging receptors over dissolving in bulk aqueous environments, supporting their strong therapeutic interactions with these receptors. These findings shed light on the molecular mechanisms underlying vitamin D's potential anti-aging effects and lay the groundwork for developing nutraceuticals targeting aging and associated diseases. Understanding these mechanisms holds promise for future interventions aimed at promoting healthy aging and enhancing overall well-being.
Supercapacitive Swing Adsorption for Direct Air Capture
Authors: Li Jiajie , Bilal Muhammad , Landskron Kai
Published: October 2024

Supercapacitive Swing Adsorption has been investigated for Direct Air capture applications. Experiments have been carried out with three different activated carbon electrode pairs derived from garlic roots at -1V and with 1M MgCl2 as electrolyte using 400 ppm CO2 in N2 as the gas mixture. Sorption capacities between 30 and 37 mmol/kg have been measured which is about six times smaller compared to benchmark experiments with a 15%CO2/85%N2 gas mixture. The weak dependency of the sorption capacity from CO2 partial pressure can be explained by the ionic liquid-solid mechanism which is based on strong electrostatic forces between the electrodes and ions formed from CO2 hydrolysis. The adsorption rates are about an order of magnitude smaller for 400 ppm CO2 compared to 15% CO2 due to the higher impact of gas flow rates and greater CO2 dilution. The energy consumption varies between 492 and 697 kJ/mol which is an increase of a factor of 9-12 compared to the 15% CO2/85% N2 gas mixture. The higher energy consumption is mainly due to the lower sorption capacity and the longer potential holding times needed at 400 ppm CO2.
Django Unleashed: A Deep Dive into the Features and Advantages of the Django Framework
Authors: Dhadil Shubham , Srivastava Anshul , Shinde Vidya , Walhekar Vinayak , Patil Ashwini , Ganeshpurkar Ankit , Karthikeyan M , Kulkarni Ravindra
Published: October 2024

Django is a powerful framework for developing web applications enabling researchers and students to efficiently access and analyse organic compound data contributing to improved patient care and safety. Its security data modelling integration capabilities and user friendly interfaces make it an excellent choice for building systems that assist in reaction planning and retro synthesis enhancing the efficiency and effectiveness of chemical research and development. This paper presents a comprehensive review on the core features user friendliness and extensive documentation of the framework providing guidance and instructions on how to integrate it with these and other technologies empowering developers to create robust and innovative web applications.
Chromosome-specific barcode system with centromeric repeat in cultivated soybean and wild progenitor
Authors: Tek Ahmet L , Nagaki Kiyotaka , Yıldız Akkamış Hümeyra , Tanaka Keisuke , Kobayashi Hisato
Published: October 2024

Wild soybeanGlycine sojais the progenitor of cultivated soybeanGlycine max. Information on soybean functional centromeres is limited despite extensive genome analysis. These species are an ideal model for studying centromere dynamics for domestication and breeding. We performed a detailed chromatin immunoprecipitation analysis using centromere-specific histone H3 protein to delineate two distinct centromeric DNA sequences with unusual repeating units with monomer sizes of 90–92 bp (CentGm-1) and 413-bp (CentGm-4) shorter and longer than standard nucleosomes. These two unrelated DNA sequences with no sequence similarity are part of functional centromeres in both species. Our results provide a comparison of centromere properties between a cultivated and a wild species under the effect of the same kinetochore protein. Possible sequence homogenization specific to each chromosome could highlight the mechanism for evolutionary conservation of centromeric properties independent of domestication and breeding. Moreover, a unique barcode system to track each chromosome is developed using CentGm-4 units. Our results with a unifying centromere composition model using CentGm-1 and CentGm-4 superfamilies could have far-reaching implications for comparative and evolutionary genome research.
The Legal Protection for the Recognition of Customary Right in Agrarian Regulations
Authors: Indriasari Evy , Widyastuti Tiyas Vika
Published: October 2024

The purpose of this research, to find out the extent to which customary law community land rights are recognized in Indonesian legislation. This article is legal research type of library research by using a statutory regulatory approach (Statute Approach). For customary law communities, Land is part of their lives that is controlled and managed jointly with the responsibility given by nature to maintain and protect it. In reality, a lot of customary land has been taken by the government and used as agricultural land, Even though customary law communities have legal standing regulated in the 1945 Constitution, Law Number 5 of 1960 concerning Basic Regulations on Agrarian Principles, MPR Decree No. IX/2001, Law Number 39 of 1999 concerning human rights. However, in reality, the government still takes customary land which is then given to investors to manage. This of course infringes the rights of customary law communities. This problem is exacerbated because in article 5 paragraph (1) of Law number 41 of 1999 concerning Forestry states that customary forests are part of state forests.
The Development of Android Based on Legal Protection System for Women and Children
Authors: Hazilina Hazilina , Alkadri Syarifah Putri Agustini
Published: October 2024

The issue of protecting women and children is becoming a concern in many parts of the world, including Indonesia. Applications can help women and children face dangerous conditions, increase public awareness, and empower them in handling cases of sexual harassment, requiring alternative technology-based solutions. The research method is juridical-empirical using a positivism paradigm, with a population of Pontianak city. Data was collected through literature study, documentation, and questionnaires. The legal protection for women and children in Pontianak City in terms of overcoming violence was found to be good, The community believed that the government was not adequately addressing incidences of abuse against women and children. Supporting factors suggest that the public can be helped by reporting acts of violence online.