bluuebunny/crossref_metadata_2025 huggingface dataset:
Medially Based Hallux Interphalangeal Joint Arthroplasty in the Management of Hallux Ulceration: Surgical Technique and Result in Six Consecutive Cases
Authors: Ehredt Duane , Reiner Matthew , Schnack Lauren , Reardon Brennan
Published: June 2023

Introduction. Plantar hallux wounds are common in patients with diabetic neuropathy. Several techniques, both surgical and nonsurgical, are designed to offload plantar wounds. However, controversy exists regarding which techniques are superior in terms of efficacy, safety, and longevity. Objective. This manuscript presents a simple, minimally invasive technique to permanently offload the plantar IPJ of the hallux in the case of recalcitrant plantar ulcerations. The authors describe their surgical technique for and outcomes of medially based hallux IPJ arthroplasty for the management of recalcitrant hallux ulcerations. Materials and Methods. Five patients (6 wound cases) were evaluated. All patients underwent the same surgical procedure and were subject to the same postoperative protocol of full weight-bearing as tolerated. Results. All 5 cases healed, with an average time to healing of 15.5 days (range, 10–22 days) and no instances of recurrence. The average time to final follow-up was 83.17 weeks (range, 54–95 weeks). Conclusions. The medially based hallux IPJ arthroplasty approach has demonstrated ability to adequately offload hallux ulcerations, permits bone biopsy or resection for treatment of underlying bone infection, and allows for immediate weight-bearing.
Unexpected single ligand occupancy and negative cooperativity in the SARS-CoV-2 Main protease
Authors: Albani Simone , Costanzi Elisa , Hoang Gia Linh , Kuzikov Maria , Frings Marcus , Ansari Narjes , Demitri Nicola , Nguyen The Toan , Rizzi Valerio , Schulz Jörg Bernhard , Bolm Carsten , Zaliani Andrea , Carloni Paolo , Storici Paola , Rossetti Giulia
Published: June 2023

Many homodimeric enzymes tune their function by exploiting either negative or positive cooperativity between subunits. In the SARS-CoV-2 Main protease (Mpro) homodimer, the latter has been suggested by symmetry in most of the 500 reported protease/ligand complex structures solved by macromolecular crystallography. Here we apply the latter to both covalent and non-covalent ligands in complex with Mpro. Strikingly, our experiments show that occupation of both active sites of the dimer originates from an excess of ligands. Indeed, co-crystals obtained using a 1:1 ligand/protomer stoichiometry leads to single occupation only. The empty binding site exhibits a catalytic-inactive geometry in solution, as suggested by molecular dynamics simulations. Thus, Mpro operates through negative cooperativity, with asymmetric activity of the catalytic sites. This allows it to function with a wide range of substrate concentrations, making it resistant to saturation and potentially difficult to shut down - all properties advantageous for the virus’ adaptability and resistance.
Estimates of cost-price passthrough from business survey data
Authors: Dogra Keshav , Heise Sebastian , Knotek Edward S. , Meyer Brent , Rich Robert W. , Schoenle Raphael S. , Topa Giorgio , van der Klaauw Wilbert , Bruine de Bruin Wändi
Published: June 2023

We examine businesses' price-setting practices via open-ended interviews and in a quantitative survey module with business contacts from the Federal Reserve Banks of Atlanta, Cleveland, and New York in December 2022 and January 2023. Businesses indicated that their prices were strongly influenced by demand, a desire to maintain steady profit margins, and wages and labor costs. Survey respondents expected reduced growth in costs and prices of about 5 percent on average over the next year. Backward-looking, forward-looking, and hypothetical scenarios reveal average cost-price passthrough of around 60 percent, with meaningful heterogeneity across firms.
Rare Neurodegenerative Disease: Systematization of Nursing Care in Patients Affected by Huntington’s Disease
Authors: Pastorini Gonçalves Thamyris Lucimar , Rodrigues Tadeus Vivian , Castro Campello Thaynara Naiane , Nascimento Xavier Jamaira do , Oliveira Naime Ramos , Fogaça Rabito Lucas Benedito , De Sousa de Lima Bruna Daniella , Flávio Gabriel Guembarski , Menezes Alves Cristiano Lucas , De França Andonai Krauze , De Assis Canizares Vivian Susi
Published: June 2023

Huntington’s disease is a rare neurodegenerative condition of genetic origin, which incapacitates the patient in carrying out daily activities over time and that has no cure. Thus, the monitoring of these individuals through systemized nursing is essential to reduce the impacts of the disease, because it allows a holistic look into the needs of the affected by professionals. This article elaborates on the systematization of nursing care to Huntington’s disease patients and their families. 3 clinical cases of the disease were selected, data collection was performed from October 1–November 30, 2018. The study enabled the development of actions based on the real needs of individuals and facilitated the development of nursing care.
Does Sinapic Acid Provide Neuroprotection Against Cisplatin-Induced Toxicity in HT-22 Cells?
Authors: Çiçek Betül , Genç Sıdıka
Published: June 2023

Objective: The aim of this study was to explain the benefits and possible protective mechanisms of sinapic acid (SA) against cisplatin-induced oxido-inflammatory damage in HT-22 rat hippocampal cells by biochemical and molecular methods. Materials and methods: Sinapic acid (SA) was applied at different concentrations (100, 400, and 800 μM) before cisplatin treatment on HT-22 cells under in vitro conditions to elicit neuroprotective activity. Half an hour after SA treatment, 5.5 μM cisplatin was added to all wells except the control group and incubated for 24 hours. Cell viability was determined by 3-(4,5-dimethyl thiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and cytotoxicity was determined by lactate dehydrogenase (LDH) assays. Oxidative stress was evaluated by total antioxidant capacity (TAC), catalase (CAT), glutathione reductase (GSH), malondialdehyde (MDA), and superoxide dismutase (SOD) assays. In addition, the effect of SA on Caspase-3 gene regulation in HT-22 cells was investigated by real-time PCR. Results: Cisplatin decreased cell viability by approximately 40% and increased LDH level in HT-22 cells. In SA-treated groups, cell viability increased and LDH level decreased dose-independently. SA showed neuroprotective activity by inhibiting the cytotoxic activity of cisplatin and increasing the antioxidant activity in cells. Similarly, Caspase-3, which was up-regulated by cisplatin, approached the control value upon SA administration. SA eliminated the neurotoxicity of cisplatin and significantly reduced cell death and oxidative stress. Conclusion: The results of this study indicate that SA protects HT-22 cells against cisplatin by inhibiting both the formation of oxidative stress and induction of cell apoptosis.
On Quasi-ideals and Bi-ideals in AG-Rings
Authors: Prommai Tanaphong , Gaketem Thiti
Published: June 2023

In this paper we study some properties of quasi-ideals and bi-ideals in AG-ring and study some interesting properties of these ideals.
Sentiment Analysis of Cryptocurrency Trading Platform Service Quality on Playstore Data: A Case of Indodax
Authors: Kamrozi  , Achmad Nizar Hidayanto  , Krishna Yudhakusuma P.M.  , Muh. Alviazra Virgananda  , Ryan Randy Suryono
Published: June 2023

Indodax is one of the cryptocurrency trading platforms in Indonesia that has the highest sentiment for the quality they provide, good quality on a platform is an important factor in obtaining user satisfaction and will have an impact on the long-term success of a company. The importance of user satisfaction on cryptocurrency online trading platforms is a significant factor in increasing user loyalty in today's competition. This research was conducted to analyze the quality of existing cryptocurrency trading platform services so that they can be input for cryptocurrency trading service providers to improve the quality of their services, this information can also be considered by prospective platform users in choosing a trading platform that has the best quality of service to minimize losses that may be caused by the platform. In this study, sentiment analysis was used for indodax play store platform users and then processed using the lexicon classification method to produce sentiment analysis for each significant factor of service quality. From the results of the classification carried out in this study, the results of the analysis show that most users are satisfied and give positive sentiments related to security, namely 87.63%, positive sentiments related to the interface design 88.46%, positive sentiments related to service & convenience by 83%, but some users also gave a slightly positive sentiment related to administrative costs, namely 39%, and their negative sentiment was mostly related to the error & failure system, which received more than 80% sentiment. While the recall value is 38.07%, the precision is 56.69% and the f1-score is 45.55%. The results of this study can be concluded that there are still many important points that must be improved in quality by the indodax platform service providers so that they can be more attractive and used by everyone.
Automatic Requirements Engineering: Activities, Methods, Tools, and Domains – A Systematic Literature Review
Authors: Delima Rosa , Khabib Mustofa  , Anny Kartika Sari
Published: June 2023

Requirements engineering (RE) is an initial activity in the software engineering process that involves many users. The involvement of various users in the RE process raises ambiguity and vagueness in requirements modeling. In addition, traditional RE is a time-consuming activity. Therefore various studies have been conducted to support process automation on RE. This paper conducts a systematic literature review (SLR) to obtain information about RE automation related to RE activities, methods/models, tools, and domains. SLR is done through 5 main stages: definition of research questions, conducting the search, screening for relevant papers, data extraction, mapping, and analysis. The data extraction and mapping are carried out on 155 relevant publications from 2016 to 2022. Based on the results from SLR, around 53% of the research focuses on RE automation in analysis and specifications, 40% focuses on elicitation, validation, and requirements management, and 7% focuses on requirements quality. NLP is the most used method in elicitation and specification, while for analysis, machine learning, NLP, and goal-oriented models are mostly used in automatic RE. Furthermore, many papers use specific models and methods for validation and requirements management. From the domain analysis results, it is obtained that more than half of the papers contribute directly to the RE domain, and some contribute to the development of RE automation in the software application domain.
Practicality and Effectiveness of the Physics Independent Learning (PIL) Model Toolkit in Online Tutorials to Improve Physics Independent Learning Skills and Physics Problem-Solving Skills
Authors: Pandiangan Paken
Published: June 2023

This study aims to analyze the practicality and effectiveness of the PIL model tool in online tutorials to improve self-learning and problem-solving skills in DL physics students in introductory quantum physics courses. This type of research is educational development research with a sample of 75 undergraduate physics education students at Universitas Terbuka in Indonesia. This research was carried out in three stages, namely preliminary and development studies, limited trials, and extensive trials. The results showed that tutors could carry out all stages of online tutorial activities using the PIL model very well with the percentage of implementation of syntax, social systems, and reaction principles. There was an increase in students' problem-solving abilities and independent learning abilities in each class after taking PIL with high N-gain categories. It can be concluded that the PIL model set is valid, practical, and effectively applied to improve problem solving skills and students' independent skills in learning Introduction to Quantum Physics.
Science Literacy of Elementary School Students through Science Practical Work Learning Method
Authors: Rokhiyah Isti , Sekarwinahyu Mestika , Sapriati Amalia
Published: June 2023

This study describes the science literacy of elementary school students who are taught using the science practical work method. The research was conducted on grade 4 and grade 5 students at six public and private elementary schools in South Tangerang City, Banten. Data collection was carried out using tests, observation sheets, student activity sheets, and questionnaires. The results showed that students had good understandings, good performance, high interest, and high self-confidence.  Moreover, students indicated good scientific attitudes and positive attitudes towards science.  The conclusion is that learning science using the science practical work method can provide elementary school students fourth grades and fifth grades showed science literacy characteristics.
TUMPANGSARI TANAMAAN PORANG (Amorphophallus muelleri Blume) DENGAN POHON KETIMUNAN (Gyrinops versteegii) DI HKM DESA PUSUK LESTARI, LOMBOK BARAT, AS AN EFFORTS TO INCREASE THE ECONOMICS OF CULTIVATORS
Authors: Mulyaningsih Tri , Muspiah Aida , Hidayati Ernin , Faturrahman Faturrahman , Hidayat Wiwin
Published: June 2023

Tanaman porang (A. muelleri) dapat memproduksi umbi yang mengandung glukomanan hingga 54% (yang bermanfaat bagi kesehatan dan bahan industri. Tanaman ini dapat tumbuh dengan baik di bawah tegakan, sehingga dapat ditumpangsarikan dengan pohon apa saja termasuk pohon gaharu yang dikonservasi secara ex situ di HKM Pusuk Lestari Lombok Barat.  Tujuan kegiatan pengabdian ini adalah memberi pengetahuan tentang budidaya tumpangsari tanaman porang dengan pohon G. versteegii yang ditanam satu tahun yang lalu untuk konservasi ex-situ di kawasan HKm Desa Pusuk Lastari, Batu Layar Lombok Barat, dan memberikan pelatihan serta praktek penanaman bibit porang dikawasan HKm dengan sistem agroforestry, untuk meningkatkan pendapatan dan kesejateraan bagi para pemangku HKm di Desa Pusuk Lestari.  Hasil kegiatan pengabdian ini adalah telah terlaksana kegiatan pelatihan tentang budidaya porang dengan metode tumpang sari dengan pohon G. versteegii, mulai dari pemilihan bibit berkualitas, pencarian distributor penjual dan pemesanan bibit porang hingga, penanganan bibit sebelum ditanam. Sedangkan praktek persiapan penanaman, seperti penyiangan lahan, penggemburan tanah, pembuatan gulutan tanah, membuat jarak tanam dan penanaman bibit porang dilakukan secara ditumpangsarikan dengan pohon gaharu jenis G. versteegii di areal HKM Pusuk Lestari Lombok Barat.
Lugol's iodine and methylene blue as an adjunctive tool for early diagnosis of premalignant oral lesions.
Authors: Waqas Iqbal  , Talha Asad Khan  , Khushbu Lohana  , Hafiz Mehmood
Published: June 2023

Objective: To compare Lugol’s Iodine and Methylene blue as an adjunctive tool for early diagnosis of premalignant oral lesions by taking histopathology as the gold standard. Study Design: Cross-sectional descriptive. Setting: Outpatient Department of Isra Dental College Hospital, Isra University Hyderabad. Period: January 2021 to July 2021. Material & Methods: All patients with oral premalignant lesions were selected. Methylene blue and iodine staining were used in the lesion area. The dye was applied directly with a cotton bud for 10–20 seconds, and the mouth was resigned with tap water. The dye retention pattern was evaluated by the stain retention intensity on the lesion. Incisional biopsy was performed simultaneously at that site as a gold standard. Results: Out of 60 cases, males were 49 (81.6%) and females were 11(18.3%). The mean age of males and females was 41.910.7 years and 39.87.74 years, respectively. Out of all patients, 65.0% had more than one addictive habit of mainpuri, gutka, or supari. The commonest region of oral lesions was the buccal mucosa among 61.6% of patients, followed by the alveolus in 16.6%, lips 8.3%, tongue 6.6%, and retro molar area 3.33%, while the palate and floor of the mouth were involved in 1.66% of patients. According to the diagnostic accuracy of methylene blue, the sensitivity was 89.4% and the specificity was 66.6%. According to the Lugol’s, iodine sensitivity was 83.3% and specificity was 50%. Conclusion: It has been determined that methylene blue and lugols iodine staining are the best, easy, and noninvasive screening tools to detect the early diagnosis of malignancy.
LigaSure hemorrhoidectomy vs Milligan morgan hemorrhoidectomy: A Quasi-Experimental Study.
Authors: Sarwat Bibi  , Khurram Saqib  , Ifrah Irfan  , Muhammad Hamza Rana  , Sumara Tabbasam  , Humaira Ahmad
Published: June 2023

Objective: To explore the efficacy of two surgical procedures by comparing the mean operative time, average blood loss and postoperative pain score during conventional and LigaSure. Study Design: Quasi-experimental study. Setting: Department of Surgery, Aziz Fatimah Hospital, to compare the efficacy of two surgical procedures regarding perioperative and postoperative variables. Period: One Year (1st July 2020 -30th June 2021). Material & Methods: Sixty patients with grade three and four haemorrhoids were randomized into two groups with 30 patients each. A questionnaire comprising all the variables was filled out and analyzed in SPSS 21. Results: Thirty patients were randomized into two groups, with group A comprising 21 (70%) females and, 9 (30%) males and 24 (80%) females, 6(20%) males in group B undergoing conventional hemorrhoidectomy. The study was single-blind, as the patients were unaware of the procedure they underwent. The mean age in group A was 39 years, and in group, B was 43 years. The mean operative time calculated was 38.4±2.77 and 51.7±2.60 in LigaSure and Milligan Morgan Hemorrhoidectomy, respectively, with a P-value calculated <0.00001. The average blood loss in LigaSure was 31.3 ± 5.76 and 49 ± 7.11 in Milligan morgan hemorrhoidectomy. Moreover, the pain assessment score on day one and all other variables were statistically significant, with a P-value of <0.00001. Conclusion: Ligasure hemorrhoidectomy is a safer surgical procedure associated with less operative time, blood loss and postoperative pain with shorter hospital stay and rapid wound healing.
Prevalence of nosocomial infection Pre- and Post-COVID 19 Pandemic in a Tertiary Care Hospital in Karachi.
Authors: Mahvesh Mahmud  , Ashok Kumar  , Mariam Ali  , Sareema Eman Akhtar  , Saad Shakil  , Maryam Anwar
Published: June 2023

Objective: To evaluate the role of the COVID-19 pandemic in the prevalence of nosocomial infections in patients admitted to the Ziauddin University Hospital, Clifton Campus, Karachi. Study Design: Retrospective Cross-sectional study. Setting: Ziauddin University Hospital, Clifton Campus, Karachi. Period: Pre-COVID: Feb 1, 2019 – Jan 31, 2019 Post-COVID: May 1 2020- Apr 30, 2021. Material & Methods: Clinicians retrospectively reviewed all Infectious Disease Department medical records for a list of all patients who developed a NI after 48 hours of admission to the hospital. The diagnosis of NI had been formulated by clinicians on the basis of clinical, radiological and microbiological findings. Results: We found an increase in certain types of NIs, and stability in the infection rate for many other organisms, which may be due to improved infection control practices during COVID. This information will lead to a better understanding of infection control practices in the future, and will better guide clinical decision making. Conclusion: The strict and proper implementation of infection control protocols during the COVID-19 outbreak has reduced the rate of NIs. It has been evident that NIs can be minimized by creating a positive attitude, improving awareness and staff hygiene practices and behaviours, and the provision of facilities to comply with the of infection control protocols’ standards.
Early complications following modified radical mastectomy in patients with breast.
Authors: Shabab Hussain  , Khan Karim Afridi  , Viqar Aslam  , Mohammad Nasir  , Fazal Ahmad
Published: June 2023

Objective: To investigate the early complications, associated comorbidities and risk factors associated with modified radical mastectomy in patients suffering from breast cancer. Study Design: Prospective Cohort study. Setting: Department of Surgery, Khyber Medical University, Institute of Medical Sciences, District Headquarter Hospital, Kohat. Period: January 2021 to December 2022. Material & Methods: A total of 65 patients diagnosed with breast cancer who were planned to undergone through radical mastectomy during the study period were analyzed. Demographical and clinical characteristics of all patients were noted. Early complications, associated comorbidities and related risk factors were recorded. Results: In a total of 65 patients, the mean age was 47±13 years (ranging 50-65 years). At the time of enrollment, 25 (38.5%) patients had painful lump in their breasts while remaining 40 (47.7%) patients reported that they were had swelling in their axillary region. There were 30 (46.2%) patients who had had stage-III breast cancer whereas other 34 (52.3%) were suffering from stage-II breast cancer. Formation of seroma was most commonly associated complication reported in 30 (46.2%) patients whereas 10 (15.4%) patients reported infections of wound. Twenty (30.8%) patients reported that they were having pain on the site of surgery along with paresthesia on the medial side of arm. Five (7.7%) patients had associated diabetes while 8 (12.3%) patients were overweight with their body mass index (BMI) value between 25-29.9 kg/m2. Nine 9 (13.8%) patients were hypertensive. Conclusion: Most common early complications associated with modified radical mastectomy included infection of the surgical site, paresthesia and pain.
Audio feature extraction: Foreground and Background audio separation using KNN algorithm
Authors: Pankaj Ramakant Kunekar  , Koushal Sunil Sadavarte  , Prajwal Rajshekhar Khambad  , Rohan Baban Lokhande  , Manasi Babusha Kharat
Published: June 2023

Data Science is a fairly novel field, and it predominantly deals with analysis and assortment of data. Machine Learning is a field that goes hand in hand in this regard. Various Algorithms, which are trained on a dataset predict results based on their training, and thus the accuracy of a model is determined by the testing dataset. Foreground feature extraction is another interesting application. Using data visualization and processing, we can plot the graphs for the audio frequency and intensity. This proves useful in feature extraction using MFCC (Mel-frequency cepstral coefficients).
Hygroscopicity of butterfly-pea under room temperature: Effect on sorption and physicochemical properties
Authors: Mohamad Efendi  , La Choviya Hawa  , Yusuf Wibisono
Published: June 2023

This study aimed to determine the phenomenon during sorption on the whole dried and powder butterfly pea under room temperature storage. In addition, identified thermodynamics, hygroscopicity, degree of caking, and physicochemical properties to determine the quality of dried butterfly pea. Experiments applied the static gravimetric method by saturated salt at 13-27oC. The study results found that the best model was the Peleg Model. The increase in aw affects the increase in EMC during sorption. The comparison results indicated that the EMC of whole dried butterfly pea was smaller than that of powder. The net isosteric heat and differential entropy indicate a decrease with increasing EMC. However, spreading pressure indicates an increase with increasing aw. Dried butterfly pea has a hygroscopicity characteristic in the extremely hygroscopic category, and it was again identified that the degree of caking of butterfly-pea powder. Recommendations for drying and storage are carried out until the moisture content is 21.57% kg H2O/kg butterfly-pea solid (whole); 22.45% kg H2O/kg butterfly-pea solid (powder). The whole and powder butterfly-pea storage increased in L* and ΔE attributes and decreased antioxidant activity with increasing time and temperature.
Biopolitische Begrenzungen und Disziplinarmacht als Spannungsfeld in Pflegschaftsverhältnissen
Authors: Hilbold Mej
Published: June 2023

Die Frage der Grenzen wird auf zwei Ebenen behandelt: zum einen die Grenzen zwischen den verschiedenen Kategorien von Kindern, die man in der Erziehungspraxis sowie in der Forschung finden kann (»die traumatisierten Kinder«, »die schwierigen Kinder« …), zum anderen die Grenzen, die den Kindern im Rahmen der pädagogischen Beziehung auferlegt werden. Diese beiden Ebenen entsprechen theoretisch zwei von Michel Foucault identifizierten Modalitäten der Macht: der biopolitischen Macht und der disziplinarischen Macht (Foucault, 1975). Im Beitrag werden die subjektiven, primär unbewusst wirksamen Effekte dieser Machtmodalitäten auf professionelle Pflegeeltern und ihr pädagogisches Handeln diskutiert. Empirische Grundlage bildet ein Forschungsprojekt über Pflegefamilien, die aus syrischen Kriegsgebieten (Islamischer Staat und später syrische oder türkische Lager) nach Frankreich repatriierte Kinder aufgenommen haben.
Krieg und Frauen
Authors: Jacke Andreas
Published: June 2023

Der Text liefert über die Rezension von Anne Carsons Theaterstück Norma Jeane Baker of Troy eine Dekonstruktion des Monroe-Mythos, der bis weit in die Vorstellungswelt ihres Privatlebens hineinreicht. Davon betroffen sind auch die Versuche, Monroes langjährige Psychoanalyse zu interpretieren, ohne die feministischen Komponenten ihrer Starimages eingehend zu betrachten.
The Prevalence of Pediculosis Capitis at Orphanages in Palembang City, South Sumatera (Indonesia)
Authors: Riswanda Jhon , Anwar Chairil , Zulkarnain Mohammad , Sitorus Rico Januar , Ghiffari Ahmad
Published: June 2023

Pediculosis capitis is an endemic parasitosis affecting many countries of the world. A total of 5318 elementary schoolchildren, aged 8 –16 years, were examined for the presence of Pediculus capitis. The aim of this study was to investigate the incidence of head lice infestation in Palembang City. This research is a quantitative research with cross sectional research design. This research was conducted at the Palembang City Orphanage.. This research took place from July to September 2021. The research population was taken from orphanage children in 16 orphanages from 12 sub-districts in the city of Palembang as many as 3.823 peoples. The sample of this research is 300 people. The sampling technique in this study was by random sampling. Data collection using a questionnaire. Data analysis with chi-square test. The results of the research are the Prevalence of Pediculosis Capitis at Orphanages in Palembang City, South Sumatera (Indonesia) from 300 peoples found that the prevalence rate in urban areas (n=155) the highest number of sufferers was found in the Sako sub-district with 18 people (11.6%) and in rural areas (n=145) the number of sufferers was found in 2 research locations, namely in Indralaya 1 as many as 36 people (24.8%) and East Baturaja as many as 40 people (27.6%). Factors associated with Pediculosis Capitis at Orphanages in Palembang City, South Sumatra (Indonesia), namely such as children’s health care (p-value=0.046), use of tools together p-value=0.004), children living with parents (p-value= ≤ 0.001), past infestation of fleas (p-value=0.027), lighting conditions of residential space (p-value=0.005) , teacher health education in schools (p-value=0.007), using general items (p-value=≤ 0.001), room conditions per student (p-value=0.028), and number of hairbrushes per day (p-value=0.016). Based on these results, it is suggested to the orphanage to provide socialization or health education as a preventive measure for Pediculosis capitis in order to increase knowledge and quality of personal hygiene in the orphanage by changing the attitude of each individual, especially children.

 

Keywords: Pediculosis capitis, Hair lice infestation
Analysis of Environmental Sanitation Risk Factors Scabies in Adolescents
Authors: Gustina Mely , Yorita Epti
Published: June 2023

Scabies is an infectious disease that affects all races and groups worldwide but is more common in children and young adults. Meta-analysis found that occupancy density, temperature, light, clean water, ventilation, gender, personal hygiene, knowledge, and contact with sufferers were risk factors for scabies in adolescents living in Islamic boarding schools. Research is needed by identifying close contact cases in the community, especially in high-risk groups such as students who live in dormitories. This study aims to analyze the factors associated with the incidence of scabies in young women at the Makrifatul Ilmi Islamic Boarding School, South Bengkulu Regency. The research design was cross-sectional, with the dependent variable being knowledge, age, personal hygiene, and environmental sanitation, while the dependent variable was the incidence of scabies. A sample of 50 teenagers was taken by accidental sampling technique. Data collection was carried out using a questionnaire and an observation sheet. Data were analyzed univariately with frequency distribution tables, bivariate with chi-square, and multivariate logistic regression. The study's results found a relationship between gender and scabies, p=0.00, and there was a relationship between knowledge and scabies, p=0.00. There is a relationship between personal hygiene and scabies p=0.00. There is a relationship between environmental sanitation and scabies p=0.00. Environmental sanitation is the most dominant risk factor associated with scabies. Health service providers must work with non-health workers, including pesantren supervisors, parents, health workers, and health cadres, in conducting education, prevention, and treatment to ensure mite elimination and break the transmission.

Keyword:  Sanitation, Personal hygiene, Scabies knowledge
A Study on Conversion of Farmland in Agricultural Promotion Areas under the Agricultural Land Act
Authors:   Korean Public Land Law Association, Jeong Gyeong-Mo , Yoon Jang-No
Published: June 2023

Article 121, Paragraph 1 of the Constitution stipulates the principle of tillage in relation to farmland. Ownership of farmland is owned by the person who uses the farmland to farm. On the other hand, Article 122 of the Constitution permits development by stipulating that necessary restrictions and obligations may be imposed in accordance with the law for the efficient and balanced use, development, and preservation of the national land. Representative development laws include the “Act on the Promotion of Exchanges between Cities and Rural Communities” and the “Basic Act on Agriculture, Rural Communities and Food Industry”. It is to improve the quality of life of rural residents and to enhance the economic vitality of rural areas. In order to achieve this goal, agricultural land is converted and developed. In order to stably supply safe agricultural products and high-quality food to the people, warehouses or factories are established. At this time, farmland in the agricultural promotion area, which is an agricultural and forestry area where the price of land is relatively low, is preferred. At this time, farmland development is mostly carried out as a small-scale project. When small-scale farmland is developed, the connectivity of farmland deteriorates, which interferes with the automated farming method of farming, resulting in a decrease in agricultural productivity. And it is causing the reckless development of agricultural land. There is a problem that farmers who need farmland cannot purchase farmland due to the increase in land price due to farmland development, which hinders the improvement of farmers' income. This study examines the basic concept of farmland, the purpose of designation of agricultural promotion areas, and the details of permission (consultation) for farmland conversion. The purpose is to derive problems from the perspective of farmland conservation following conversion permission (consultation), and to present the contents to be improved to help preserve farmland even a little.
The World Formula and the Theorem of Perron-Frobenius: How to Solve (Almost All) Problems of the World
Authors: Fehlmann Thomas , Kranich Eberhard
Published: June 2023

Transfer Functions relate the output or response of a system such as a filter circuit to the input or stimulus . The response can be measured; the is the unknown. Solving the World Formula not only explains how analog images and voice can be digitally stored, but also many methods and techniques such as Big Data and Artificial Intelligence. For linear functions between vector spaces, the Eigenvector Method makes calculating a solution easy, if it exists. Numerical algorithms are available for solving. Thus, the method is suitable for teaching students who are interested in the foundations of science. However, the system must meet certain conditions to make the eigenvector method applicable. The Theorem of Perron-Frobenius defines these conditions. Keywords: transfer functions, big data, world formula, Eigenvector method, theorem of Perron-Frobenius
Reimagining the Gender and Class Dynamics of Premodern Composition
Authors: Ahuvia Mika
Published: June 2023

This article argues that recent scholarship on premodern composition can help to reconceptualize the presence of diverse people, including enslaved women, in scribal spaces. A brief historiographic section reviews how scholars have imagined normative Jews to be elite literate men, neglecting evidence of dictation to scribes, and thus excluded evidence of lower-class women especially from their imagining of the past. Applying Wendy Doniger’s rejection of the category of the singular male author in religious texts to Jewish texts, it proposes a heuristic tool to identify women’s presence and perspectives in ancient prose, liturgical, and ritual texts. Finally, it analyzes four incantation bowls as test-cases of this approach. For every text produced by a scribe, scholars ought to imagine a dynamic compositional environment with at least two people, and they can look for evidence of inclusion and exclusion of perspectives based on religious markers, class status, and gendered concerns.
Profil Berpikir Komputasi Siswa dengan Menggunakan Model Pembelajaran Problem Based Learning (PBL) Ditinjau dari Gaya Belajar di SMA N 1 Langsa
Authors: Litia Nindy , Sinaga Bornok , Mulyono Mulyono
Published: June 2023

Penelitian ini bertujuan untuk mengetahui: (1) Tingkat kemampuan berpikir komputasi siswa dengan menggunakan model pembelajaran Problem Based Learning (PBL). (2) Profil berpikir komputasi siswa ditinjau dari gaya belajar Kolb dalam penerapan model pembelajaran Problem Based Learning (PBL). Penelitian ini merupakan penelitian kualitatif dengan pendekatan deskriptif. Subjek dalam penelitian ini siswa kelas XI MIA 4 SMAN 1 Langsa, dengan instrumen angket gaya belajar tipe Kolb, tes kemampuan berpikir komputasi siswa, wawancara dan dokumentasi. Hasil penelitian menunjukkan bahwa (1) Hasil tes tingkat kemampuan berpikir komputasi siswa dengan menggunakan model pembelajaran Problem Based Learning (PBL), siswa kategori rendah berjumlah 9 orang (25%), siswa kategori sedang berjumlah 15 orang (41,44%), sedangkan siswa kategori tinggi berjumlah 12 orang (33,33%). Untuk tingkat kemampuan berpikir komputasi siswa yang paling dominan berada di kategori sedang. (2) Profil subjek MS yang memiliki gaya belajar converger dengan indikator dekomposisi (4 dan 90.33%); pengenalan pola (3 dan 88.35%); berpikir algoritma (3 dan 72.85%); Abstraksi dan Generalisasi Pola (3 dan 69.71%). Profil subjek DYZ yang memiliki gaya belajar Diverger dengan indikator dekomposisi (4 dan 90.33%); pengenalan pola (3 dan 80.15%); berpikir algoritma (3 dan 71.85%); Abstraksi dan Generalisasi Pola (3 dan 69.40%).
Caracterización del combustible del dosel arbóreo mediante sensores remotos y evaluación del efecto de las claras sobre el comportamiento y severidad potenciales del fuego en pinares del NO de España
Authors: Arellano Pérez Stéfano , Ruiz González Ana Daría , Vega Jose Antonio , Álvarez González Juan Gabriel
Published: June 2023

En la presente tesis doctoral se han desarrollado modelos para estimar la distribución vertical de la carga de combustible disponible del dosel arbóreo, tanto a partir de datos LiDAR como de variables de rodal medidas en campo. Además, se han obtenido modelos de estimación de variables del combustible de superficie y del dosel arbóreo a partir de imágenes del satélite Sentinel-2A, que permiten generar cartografía del riesgo potencial de fuego de copas. Por otro lado, se ha evaluado el efecto a medio plazo del tratamiento de clara por si sola, sin intervención en los combustibles de superficie, sobre el complejo de combustible y el comportamiento y la severidad potenciales del fuego, así como la capacidad de los rodales quemados para proteger el suelo contra la erosión post-incendio. Todos estos estudios se realizaron en pinares del noroeste de España y los resultados obtenidos aportan nueva información sobre combustibles forestales, conectándola con el comportamiento esperado del fuego en incendios, siendo de gran utilidad no sólo en la gestión del fuego forestal sino también en la gestión forestal en general.
The Role of Immunotherapy in Cancer Treatment: Harnessing the Power of the Immune System
Authors: ansari zeeshan
Published: June 2023

The Role of Immunotherapy in Cancer Treatment: Harnessing thePower of the Immune System
The Impact of Exercise on Cancer Prevention and Treatment: A Comprehensive Review
Authors: ansari zeeshan
Published: June 2023

The Impact of Exercise on Cancer Prevention and Treatment: AComprehensive Review
Enhancing Flood Risk Assessment Through Machine Learning and Open Data
Authors: Narock Tom , Johnson J , Modaresi Rad Arash
Published: June 2023

Urban flooding causes billions of dollars in damages annually, with severe flood events becoming more frequent and destructive as our climate changes. While extreme weather is a primary driver of flooding, its consequences depend on the interconnectedness of urban systems - referred to as the Urban Multiplex, which includes the power grid, transportation network, natural surface water and groundwater systems, sewerage and drinking water systems, intertwined with the socioeconomic and public health sectors. One component of this multiplex - a reliable buildinginventory - is critical for assessing the number of people affected by flooding, the propagation of shocks throughout the economy, and for forecasting detailed socioeconomic risk from flooding. Yet, a major discrepancy exists in the way data about buildings are collected across the U.S. There is no harmonization in what data are recorded by city, county, or state governments, let alone at the national scale. We demonstrate how existing open source datasetscan be spatially integrated and subsequently used as training for machine learning models. These machine learning models can then predict building occupancy type, a currently lacking component of flood risk assessment. Multiplemachine learning algorithms are compared and an application to the 100-year flood in North Carolina is provided. Results indicate that a 100-year flood will disproportionately impact Mecklenburg, Wake, Dare, and Brunswick counties.
Cognitions and Emotions about Child Sexual Abuse (CECSA): Development of a Self-Report Measure to Predict Bias in Child Sexual Abuse Investigations
Authors: Gewehr Elsa , Volbert Renate , Merschhemke Marie , Santtila Pekka Olavi , Pülschen Simone
Published: June 2023

A biased mindset can foster confirmatory reasoning and suggestive questioning when adults talk to children about abuse suspicions in child-protection, healthcare, educational or investigative settings. We developed a self-report instrument on Cognitions and Emotions about Child Sexual Abuse (CECSA) that may predict individual propensity for a bias toward the abuse hypothesis. Three subscales, 23 items in total, were created in a sample of 801 students of human sciences via exploratory factor analysis and Ant Colony Optimization. The “Naïve Confidence” subscale reflects overestimating one's ability to recognize abused children and overestimating the accuracy of children’s abuse reports, the "Emotional Reactivity" subscale measures the intensity of one's emotional reactions towards the topic of child sexual abuse (CSA), and the "Justice System Distrust" subscale covers distrusting the justice system’s ability to prosecute CSA. The CECSA showed adequate model fit and good internal consistencies. Correlations with other self-report measures demonstrated convergent validity. All subscales predicted biased evaluations towards the abuse hypothesis in scenarios of children displaying unspecific behavioral problems. Given context-specific validations, the CECSA may be used to evaluate training programs or to assess training needs of professionals who talk to children about CSA suspicions.
Feedforward connectivity patterns from visual areas to the front of the brain contain information about sensory stimuli regardless of awareness or report
Authors: Rowe Elise , Garrido Marta , Tsuchiya Naotsugu
Published: June 2023

Current theories of consciousness can be categorized to some extent by their predictions about the putative role of the prefrontal cortex (PFC) in conscious perception. One family of the theories proposes that the PFC is necessary for conscious perception. The other postulates that the PFC is not necessary and that other areas (e.g., posterior cortical areas) are more important for conscious perception. No-report paradigms could potentially arbitrate the debate as they disentangle task reporting from conscious perception. While previous no-report paradigms tend to point to a reduction in PFC activity, they have not examined the critical role of the PFC in “monitoring” or “reading out” the patterns of activity in the sensory cortex to generate conscious perception. To address this, we reanalysed EEG data from a no-report inattentional blindness paradigm (Shafto & Pitts, 2015). We examined the role of feedforward input patterns to the PFC from sensory cortices. We employed nonparametric spectral Granger causality and quantified the amount of information that reflected the contents of consciousness using multivariate classifiers. Unexpectedly, regardless of whether the stimulus was consciously seen or not, we found that information relating to the current sensory stimulus was present in the pattern of inputs from visual areas to the PFC. In light of these findings, we suggest various theories of consciousness need to be revised to accommodate the fact that the contents of consciousness are decodable from the input patterns from posterior sensory regions to the PFC, regardless of awareness (or report).
Productivity and quality of winter wheat grain in crop rotations with different types of fallow and at different levels of fertilization
Authors: Dudkina T. A.
Published: June 2023

The purpose of the current work was to study the effect of various winter wheat forecrops (weedfree fallow, green fallow, sown fallow) and fertilization levels (control without fertilizers, NPK–60 kg.a.i./ha, NPK–80 kg.a.i./ha, NPK–100 kg.a.i./ha) on productivity and quality of winter wheat grain. The study was carried out at the Federal State Budgetary Scientific Institution “Kursk FARC” in 2018–2020. There has been established that the large-sized grain was grown in a crop rotation with a sown fallow. There has been established that with an increase of mineral fertilizers’ doses, the differences between crop rotations raised. In the crop rotation with sown fallow, grain evenness was also higher, by 0.3 and 0.5 % more than in crop rotations with green manure and weedfree fallow. There has been found that regardless of the crop rotation, with an increase in the dose of mineral fertilizers, grain evenness increased. There has been determined that the trait ‘1000-grain weight’ was the highest when it was sown in green fallow with 48.4 g of NPK–100 kg.a.i./ha, which was due to the improvement of the nutrient regime of the soil with the introduction of green manure. There has been determined that when growing wheat in green fallow in the variant without fertilizers, crude gluten in the flour was 2.3 and 2.5 % more than in sown and weedfree fallow. This pattern was also preserved on fertilized backgrounds. The indicator of gluten percentage in flour increased with the growth of fertilizer. There has been found that crop rotation with weedfree fallow was the best in terms of gluten elasticity. Winter wheat productivity at NPK–60 kg.a.i./ha and NPK–100 kg.a.i./ha was higher when sown in weedfree fallow, and on unfertilized control and at NPK–80 kg.a.i. / ha when sown in green fallow. There has been noted that there is a significant improvement in crop productivity, for example, from 4.39 to 6.19 t/ha in crop rotation with weedfree fallow, with an increase in fertilizer application rates.
Marker assisted selection (MAS) of spring bread wheat to improve productivity, grain quality, resistance to diseases and drought in the conditions of Western Siberia
Authors: Shepelev S. S. , Pototskaya I. V. , Chursin A. S. , Morgunov A. I. , Shamanin V. P.
Published: June 2023

The challenges at the modern consumer market, climate change, an increase in the number of epiphytotic and arid years dictate the necessity to accelerate wheat breeding for a whole range of traits and, above all, those associated with an improvement of productivity, grain quality, resistance to diseases and drought. Marker assisted selection (MAS) allows reducing time for developing varieties with specified parameters in the conditions of a particular region. The purpose of the current work was to identify KASP-markers associated with genes of valuable traits in the collection and breeding material of wheat and effective SNP-loci for marker assisted selection (MAS) in Western Siberia. Identification of genes that control economically valuable traits using 64 KASP-markers in 2020 was performed in the LGC-Genomics laboratory (Great Britain). It was found that the platforms for genotyping SNP-loci of a large number of current varieties had a significant similarity, despite the geographical separation of varieties, which indicated the vulnerability of grain production during large-scale epiphytoties and drought. There have been found differences in the identified SNP-loci and their frequency of occurrence between current varieties, ancient wheat varieties, and breeding material based on synthetic wheat. According to the results of phenotyping of the studied samples in the field seasons of 2020–2021 there has been shown a significant effect of the root system’s parameters (genes TraesCS2D01G395500.1 and TraesCS4D01G341800.1 in chromosomes 2D and 4D) on grain size and productivity improvement. The drought resistant gene TaDreb-B1 has affected on an increase of grain content of a head and productivity. The genes GPC-B1 and TraesCS2D01G316300.1, which are responsible for nitrogen remobilization, protein and dry biomass accumulation in grain, significantly contributed to the improvement of nutritional grain value and accumulation of protein in grain. Due to marker-controlled selection in the CVT, there have been identified the varieties that significantly exceeded productivity standards, with a complex of genes that have positive effects on grain quality, resistance to diseases and drought.