bluuebunny/crossref_metadata_2025 huggingface dataset:
A RETROSPECTIVE OBSERVATIONAL STUDY TO COMPARE THE EFFECT OF AGGRESSIVE VS MODERATE FLUID RESUSCITATION IN PATIENTS PRESENTING TO BMC SAGAR WITH ACUTE PANCREATITIS
Authors: Ratnakar Akhilesh , Saxena Sunil Kumar , Singh Dangi Jitendra , Kumari Aditi
Published: September 2024

Introduction : Acute pancreatitis is one of the most common causes of acute abdomen. Increased rates of hospitalization pose a signicant burden
on health care costs and resource utilization. Our aim in this study is to assess whether moderate  Objective : uid resuscitation instead of
aggressive approach would benet in the management of acute pancreatitis. :A total of 100 patients s Methods uffering from acute abdomen due to
acute pancreatitis were recruited and studied in two groups. One group was managed via moderate uid resuscitation whereas the other group was
managed aggressively in terms of uid therapy. The outcomes were measured as primary and secondary. Primary included the development of
moderately severe or severe acute pancreatitis (according to the Revised Atlanta Classication) during the hospitalization whereas secondary
compared the duration of hospital stay; intensive care unit (ICU) admission; the number of days in the ICU; the use of nutritional support and death.
Results :Out of 100 subjects enrolled, 68 were males and 32females. There was no signicant between-group difference in the development of
moderately severe or severe acute pancreatitis (primary outcome), which occurred in 22% of the patients in the aggressive-resuscitation group and
in 19% of those in the moderate-resuscitation group. Organ failure occurred in 8% of the patients in the aggressive-resuscitation group and in 4% of
those in the moderate-resuscitation group. A total of 9% of the patients in the aggressive-resuscitation group and 2% of those in the moderateresuscitation group were admitted to the ICU. Conclusion : Aggressive uid resuscitation increased the risk of volume overload. Aggressive uid
resuscitation was associated with a tendency toward a higher intensity of symptoms and a longer duration of hospital stay and a higher incidence of
necrotizing pancreatitis than moderate uid resuscitation.
BIOMEDICAL WASTE MANAGEMENT AND ITS AWARENESS AMONG REGISTERED NURSES WORKING IN DIFFERENT HOSPITALS, UTTAR PRADESH
Authors: Kumar Mukul , Jasline M , Singh Jitendra , Rastogi Muskan
Published: September 2024

The production of waste is an ongoing process. All facets of life generate trash, but medical waste is the most hazardous or deadly. Waste produced
during healthcare processes poses a higher risk of illness and injury than various kinds of waste. The aim of the study was to evaluate Registered
Nurses' knowledge regarding biomedical waste management working in different hospitals of Moradabad, Uttar Pradesh. The study design was
cross sectional. This study was conducted at TMU hospital of Moradabad. 108 Registered Nurses were selected by simple random sampling
technique. According to the study ndings, out of 108 samples, 7 (6.5%) of Registered Nurses were having adequate level of knowledge, 58
(53.7%) were having moderate knowledge and 43 (39.8%) were having inadequate level of knowledge regarding biomedical waste management.
This study concluded that most of were having inadequate level of knowledge regarding biomedical waste management.
ROLE OF USG GUIDED FINE NEEDLE ASPIRATION CYTOLOGY IN THE DIAGNOSIS OF HEPATIC LESIONS
Authors: Saikia Ankur , Sharma Adity , Borah Asha , Deori Rashmi , Dutta Aparna , Khaklari Sandeep
Published: September 2024

USG guided Fine needle aspiration cytology (FNAC) has been proven
to be a very effective means of obtaining tissue from many different
body sites for diagnosis. It was applied in liver as early as 1985.
COMPARISON OF FLUORESCENT STAIN WITH TRUENAT AND LINE PROBE ASSAY OF SPUTUM SAMPLE FOR THE DIAGNOSIS OF PULMONARY TUBERCULOSIS AT A TERITIARY CARE HOSPITAL, WARANGAL.
Authors: Padmaja Goteti Venkata , Chandra Golla Eshwara , Ramya Harshita Chilakalapalli , Kodida Hima Bindhu
Published: September 2024

Introduction: Tuberculosis (TB) a highly infectious disease. India is one among the high burdened countries responsible for more than 80%in the
world prevalence of tuberculosis. Tuberculosis persists to be a one of the notiable diseases with high mortality and morbidity. The need for fast,
precise diagnostic tests to identify active tuberculosis is essential, mainly in endemic nations such as India. An automated real-time Polymerase
Chain Reaction (PCR) method for pulmonary and extrapulmonary tuberculosis (TB) detection known as TrueNat and Line probe assay shows great
promise as a complement to conventional sputum microscopy techniques To compare sensitivity, specic Aim: ity of uorescent stain with Truenat
and Line probe assay for detecting Mycobacterium tuberculosis and drug susceptibility pattern in sputum samples A Material and Methods:
prospective comparative study on patients with suspected pulmonary TB was conducted from January 2023 to December 2023 for a period of 1
year in a tertiary care hospital at Kakatiya medical college Warangal along with DTC,Warangal, Telangana. The sensitivity, specicity, diagnostic
accuracy for the diagnosis of tuberculosis were calculated for uorescent stained smear microscopy, TrueNat, and Line probe assay and compared
with each other. In our study a total of 4000 pulmonary samples were collected with clinical signs a Results: nd symptoms and all samples were
subjected to uorescent smear microscopy, Truenat and line probe assay. Out of 4000 sputum samples, 357(8.9%) were positive for uorescent
smear microscopy ,452 (11.3%) samples were positive for Truenat among them 431(95.3%) Rifampicin sensitive and 21(4.87%) Rifampicin
resistant. In Line probe assay 452(11.3%) were positive for Mycobacterium tuberculosis, among them 431(95.3%) Rifampicin sensitive and
21(4.87%) Rifampicin resistant and 433(95.1%) isoniazid sensitive ,19(4.2%) isoniazid resistant. Tru Conclusion: eNat can be essential in sample
positive patients as a diagnostic modality, for early diagnosis and medication. It is less time consuming, but it can detect only rifampicin resistance.
Genotype MTBDRplus LPA VER 2.0 is a rapid diagnostic method for TB detection in sputum specimen and promotes accurate diagnosis of both
RMP and INH resistance, susceptibility to drugs within a short turnaround time (4 hours). It provides rapid information to opt for early treatment
and contain disease spread.
EVALUATION OF FOETAL NEURAL AXIS IN ANTENATAL SCAN AND ITS CORRELATION WITH FOETAL OUTCOME
Authors: Srivastava Suyash , Patil Gayatri , Purushottam Siddhesh , Kapoor Priti
Published: September 2024

Central nervous system malformations are among the most frequent anomalies detected at antenatal sonography, with studies suggesting a
prevalence as high as 1 in 1000. Ultrasound has become an increasingly valuable tool in identifying even the most subtle anomalies to a great
extent. Most central nervous system malformations are discovered in the second trimester around 20 weeks of gestation, when the morphology is
better recognized and targeted anomaly scans are performed as a routine practice. Even in early pregnancy, with effort and good equipment, it is
now possible to move vital structures such as the spine, skull, interhemispheric ssure, choroid plexus, thalamus, and posterior cranial fossa.
Sequential antenatal ultrasound starting early in rst trimester has played a pivotal role in diagnosing these anomalies early.
COMPARATIVE EFFICACY OF SUTURES VERSUS TACKERS FOR MESH FIXATION IN LAPAROSCOPIC TAPP INGUINAL HERNIA REPAIR
Authors: Megalamani Suheel , Nagur Basavaraj
Published: September 2024

Background:Inguinal hernia repair is a common surgical procedure, with laparoscopic approaches offering several advantages over open surgery.
However, the optimal method for mesh xation in laparoscopic inguinal hernia repair remains debated. This study aims to compare the efcacy and
outcomes of suture versus tacker xation for mesh in laparoscopic inguinal hernia repair. Methods: This comparative clinical trial was conducted
at Al Ameen Medical College, Vijayapura, involving 30 patients randomized into two groups. Group A (n=15) underwent mesh xation using
sutures, while Group B (n=15) underwent mesh xation using tackers. The primary outcomes measured were the duration of surgery, time period of
hospital stay, postoperative pain, postoperative seroma, postoperative hematoma, and postoperative hospital stay due to complications. Statistical
analysis was performed to compare the outcomes between the two groups. Results: The mean duration of surgery was signicantly shorter in the
tacker group (65.8 ± 10.3 minutes) compared to the suture group (75.2 ± 12.5 minutes) (p=0.02). Postoperative pain was signicantly lower in the
tacker group at 24 and 48 hours post-surgery (p=0.01 and p=0.02, respectively). The time period of hospital stay, incidence of postoperative
seroma, and postoperative hematoma showed no statistically signicant differences between the groups. The mean postoperative hospital stay due
to complications was also similar between the groups (p=0.62). Conclusion: Tacker xation for mesh in laparoscopic inguinal hernia repair is
associated with shorter operative times and reduced postoperative pain without increasing the risk of complications such as seroma and hematoma.
These ndings support the use of tackers as a viable alternative to sutures, potentially improving patient outcomes and surgical efciency. Further
large-scale studies are recommended to conrm these results and guide clinical practice.
CORRELATION BETWEEN 6MINUTE WALK TEST, SPIROMETRY AND HRCT CHEST IN ILD PATIENTS
Authors: Reshma Sheikh , Suryanarayana V.
Published: September 2024

Introduction: Interstitial lung diseases (ILDs) or Diffuse parenchymal lung diseases (DPLDs) are a heterogeneous group which includes more
than 200 disorders grouped together because of their similar clinical, radiological, pathological and physiological features. ILDs are classied
based on HRCT patterns. Studies shows about 14% of all interstitial lung diseases cases in India are idiopathic pulmonary brosis and an equal
number of cases are due to connective tissue disorders. Materials and Methods: This study was hospital based prospective correlational study
performed in Respiratory Medicine Department in GEMS Medical College and Hospital in Srikakulam, Andhra Pradesh, India. Results:
established signicant correlation of 6MWT, Spirometry, DLCO and HRCT chest. Conclusion: we can use these simple methods to know the
progression and response of treatment instead of using CTchest repeatedly there by decrease the exposure and cost
UNVEILING THE UNCOMMON:RARE PRESENTATIONS OF FEMALE GENITAL TRACT TUMOURS
Authors: Harrini Harrini , Bindu I N , V P Lakshmi , Janardhan Karpagam , John Rosmy
Published: September 2024

The female reproductive tract harbors many neoplastic conditions of which the most common type being leiomyomata and ovarian cysts with
genital cancers like cervical, ovarian and endometrial carcinoma being the next common. The tumours of fallopian tubes vulva and vagina are very
rare and STUMP presenting as endometrial polyp and labial mass is extremely rare. Likewise choriocarcinoma presenting as myometrial mass and
high grade endometrial sarcoma presenting as a myometrial mass in 19 year old female are rare presentations. In this case series we are presenting
these 4 female genital tract lesions with unusual presentations.
A CROSS SECTIONAL STUDY CONDUCTED TO STUDY THE RELATIONSHIP BETWEEN HbA1C LEVELS AND DIABETIC PERIPHERAL NEUROPATHY IN TYPE 2 DIABETIC PATIENTS.
Authors: P. Desai Rajat , Joshi Rachit , C. Meht Neeta , Sinha Kinjal
Published: September 2024

Introduction: Diabetes is a leading cause for development of diabetic peripheral neuropathy (DPN)in all over the world. By some parameters we
can detect the possibility of developing DPN and one of them is HbA1C.In this study it is we have tried to correlate the level of HbA1C parameter in
patients who has already developed DPN in patients with type 2 diabetes. Evidence on the efcacy of glycemic control for diabetic peripheral
neuropathy (DPN) is limited in patients with type 2 diabetes mellitus. The objective of this study was to explore correlation of development of
DPN with HbA1c level. Methodology: In this cross-sectional study total 87 patients were examined who were type 2 diabetic patients with already
developed diabetic peripheral neuropathy. Blood samples were collected to measure glycated hemoglobin (HbA1c) to indicate the glycemic status
of the subjects in patients who has presented with the symptoms of diabetic peripheral neuropathy. Results: It is noticeable that males have more
chances of development of diabetes neuropathy. It is seen that subjects with uncontrolled diabetes based on HbA1C parameter are more prone to
development of diabetes neuropathy as compare to uncontrolled ones however less chances but DNP still develop in well controlled diabetic
patients too. Statistical analysis: distribution of cases shows that among 87 patients 55.17% were males and 44.83% were females. Among them
63.28% of patients had uncontrolled diabetes (HbA1C >6) and 36.78% of patient had controlled diabetes (HbA1C <6). Conclusion: It is
concluded that development of DNP is more seen among patients having HbA1C >6, however it is also not uncommon among patients with
controlled diabetes.
A COMPREHENSIVE REVIEW OF THE COMPARISON OF LAPAROSCOPIC AND OPEN VARICOCELECTOMY TECHNIQUES
Authors: Shakya J. P. S. , Lavania Prashant , Tiwari Utkarsha
Published: September 2024

Overview And Introduction- The abnormal dilataton and convoluted pampiniform plexus of veins is known as Varicocele.The sole therapeutic
option is surgical correction .Open scrotal ,Open inguinal,Microinguinal,Subinguinal,laparoscopic ligaton and embolizaton of thetesticular vein
are among the surgical techniques that can be used. Laparoscopic varicocelectomy has several benets,including safer,higher magnicaton that
makes it easier to identify arteries,lymphatics and the internal spermatic artery with greater accuracy. In bilateral situations, there is noneed for a
second incision. Aim - The purpose of the study is to assess post-operative complication,length of hospital stay and recurrence between
laparoscopic and open varicocelectomy. Methedology- Retrospective single centre observational descriptive study conducted from September
2018 to February 2020 on 50 patients at Sarojini Naidu Medical College,Agra. Results And Conclusion-Varicocele affects 10-20% of adult males
and more than 25% of men whose semen analysis is abnormal. Approximately 90% of varicoceles are left sided, and if one is found there is a 30-
40% chance that it is a bilateral conditon.When compared to open varicocelectomy,laparoscopic varicocelectomy is a safer and more effective
procedure,resulting in a signicant reduction in operating time, minimal post-operative complication,a shorter hospital stay,increased patient
satisfaction and notable changes in pre and post -operative semen parameters
INCIDENCE OF CARDIOVASCULAR DYSFUNCTION IN PATIENTS WITH LIVER CIRRHOSIS - A HOSPITAL BASED OBSERVATIONAL STUDY
Authors: Agarwal Pradeep , Phalke Adheesh , Rijhwani Puneet
Published: September 2024

Background: Liver cirrhosis is a chronic condition marked by scarring of liver tissue, leading to signicant functional impairment. Cardiovascular
dysfunction, often referred to as cirrhotic cardiomyopathy, is a known complication in liver cirrhosis patients, characterized by altered cardiac
structure and function. Our study aimed to elucidate the incidence and nature of cardiovascular abnormalities in this patient population. Aim: To
study the incidence of cardiovascular dysfunction in patients with liver cirrhosis and its correlation with the severity of liver disease as classied by
the Child-Pugh score. Material and Methods: An observational study was conducted at Mahatma Gandhi Medical College & Hospital, Jaipur,
including 101 patients with liver cirrhosis, without any pre-existing cardiac ailments. Demographic data, liver disease severity (Child-Pugh
classication), and various cardiac function parameters were recorded. Cardiac assessments included measurements of LV ejection fraction (EF),
global longitudinal strain (GLS), septal e', E/e' ratio, TR velocity, systolic and diastolic function, QTc interval, and BNPlevels. Results:· Age and
Gender:Patients ranged from 22 to over 50 years, with the majority (41.6%) over 50 years old. The cohort included 71 males (70.3%) and 30
females (29.7%). Child-Pugh Class: 62.4% of patients were in Class A, 23.8% in Class B, and 13.9% in Class C. Cardiac Function: 28.7% had an
LV EF <50%, and 24.8% had GLS <18%, 23.8% had septal e'<7cm/second, 30.7% had E/e' >15, 28.7% had TR velocity >280cm/second.
Systolic dysfunction was present in 23.8%, and diastolic dysfunction in 22.8%. Elevated QTc intervals (>440 ms) were found in 45.5%, and 60.4%
had elevated BNP levels (>100 pg/mL). Associations: Signicant associations were found between higher Child-Pugh classes and both systolic
and diastolic dysfunction (p-value = 0.001). Conclusion:This study highlights a signicant incidence of cardiovascular dysfunction in liver
cirrhosis patients, particularly among those with more severe liver disease (Child-Pugh Classes B and C). Comprehensive cardiovascular
assessment is crucial in this population for early detection and management of cardiac complications, potentially improving overall patient
outcomes.
A COMPARATIVE STUDY TO ASSESS THE SELF-EXPRESSED STIGMA REGARDING COVID 19 AMONG RURAL AND URBAN ADULTS OF JAMMU.
Authors: Kour Gurneet , Prabu. D Israel Jeba
Published: September 2024

Objectives: 1. To assess the self - expressed stigma regarding covid -19 among rural adults of Jammu. 2.To assess the self-expressed stigma
regarding covid-19 among urban adults of Jammu. 3.To compare the self-expressed stigma regarding covid 19 among rural and urban adults of
Jammu. 4.To nd association of self-expressed stigma regarding covid 19 with selected socio demographic variables among rural adults. 5.To nd
association of self-expressed stigma regarding covid 19 with selected socio-demographic variables among urban adults. : A non- Methodology:
experimental descriptive study was carried out on hundred adults in urban and rural area of city Jammu. non-probability convenient sampling
technique was used to select the sample. Data was collected with structured questionnaire. Quantitative research approach was used for this study.
The research study was conducted at Rural area(Dhindey kalan,) and urban area(Pacca danga) of Jammu.Target population comprises of adults of
rural and urban and accessible population fullling inclusion and exclusion criteria. Total sample size of 100 adults was selected for this study. 50
each from rural and urban area. Data was analyzed with descriptive and inferential statistics as per objectives of study. The level of score Results:
of self-expressed stigma regarding covid-19 revealed that 56% of rural adults had positive self-expressed stigma, 44% had neutral and 0% had
negative self-expressed stigma. The calculated Mean and Standard Deviation of self-expressed stigma score 26.80 and 3.375. The level of score of
self-expressed stigma regarding covid-19 revealed that 14% of urban adults had positive self-expressed stigma, 86% had neutral and 0% had
negative self-expressed stigma. The calculated Mean and Standard Deviation of self-expressed stigma score 22.84 and 3.383. Regarding the
association between the level of score of self-expressed stigma for rural adults with selected socio demographic variables, the chi-square value
show that there is no signicance association between the score level and demographic variables. But in urban adults there is a signicant
association Educational Status of Adults, Occupational Status of Adults with the score. The study co Conclusion: ncluded that the positive stigma
in rural adults is higher than the urban adults whereas in neutral stigma in urban adults is higher than the rural adults.
CYCLOPHILIN A - A SURROGATE BIOMARKER FOR CORONARY ARTERY DISEASE
Authors: Ukadgaonkar Ajeya
Published: September 2024

Background: Studies have reported that Cyclophilin A (CyPA) has the potential to be a valuable biomarker of coronary artery disease (CAD). It
was found that plasma levels of CyPA correlated with the anatomical severity of CAD. Several issues remain regarding the role of CyPA as a
biomarker of CAD. An attempt is made to study correlation of plasma CyPAlevels with severity of coronary artery disease and traditional coronary
risk factors. Methods: 404 patients aged ≥ 18 years of either gender with chest pain undergoing coronary angiography (CAG) were included. They
were subjected to standard clinical evaluation, estimation of plasma CyPA by enzyme linked immunosorbent assay (ELISA) method and CAG.
Plasma CyPA levels were compared with CAG and traditional coronary risk factors. Qualitative and quantitative variables were tested using ChiSquare test and Mann Whitney U test respectively. The cut off values of CyPA across the angiographic groups were calculated using Receiver
Operating Characteristic (ROC) curve. The predictive signicance of CyPA and risk factors in detecting signicant CAD was tested using
sensitivity, specicity, positive predictive value (PPV) and negative predictive value (NPV). Results: Median CyPA levels were signicantly
higher in obstructive CAD (15.8 ng/ml) as compared non-obstructive CAD (7.8 ng/ml) and normal coronary arteries (6.0 ng/ml). Plasma CyPA
levels of >8.0 ng/mL, >9.4 ng/mL and >13.0 ng/mL reliably predicted presence of CAD, obstructive CAD and risk of ACS respectively with
excellent specicity and good sensitivity. Plasma CyPAlevels were signicantly higher in males, diabetic patients, patients with dyslipidemia, and
smokers. Conclusion: Plasma CyPAis a novel biomarker for CAD
TO STUDY THE ETIOLOGICAL, CLINICAL AND HISTOPATHOLOGICAL PROFILE OF PATIENTS WITH NON CIRRHOTIC PORTAL FIBROSIS IN A TERTIARY CARE CENTER : A HOSPITAL BASED OBSERVATIONAL STUDY
Authors: Garg Rahul
Published: September 2024

Introduction: Non cirrhotic portal brosis is a syndrome characterized by obliterative portovenopathy leading to portal hypertension, massive
splenomegaly and well tolerated episodes of variceal bleeding in young adults from low socioeconomic backgrounds, having near normal hepatic
functions. Objectives : This study was designed to evaluate the patients of NCPF for clinical , etiological and histopathological prole and
determine whether the source of drinking water could have a role in etiopathogenesis of NCPF. Materials And Methods:This retrospective study
was conducted at FH Medical College and Hospital, Agra, involving 50 diagnosed NCPF patients. Distribution of cases was done according to age,
sex, diet, source of drinking water, various clinical presentations on the basis of history and clinical examination, and histopathological ndings.
Statistical analysis was done using Chi square test and Fisher's exact test. Results: Study showed male preponderance. Most patients were in the
age group of 25-35 years, 74% were vegetarian and 46% of the patients used tap water as the source of drinking water. Major presentation of
patients with NCPF was with g.i.bleed and left upper quadrant mass on history and splenomegaly on clinical examination. Main histological
ndings were irregular intimal thickening of portal veins, and organizing thrombosis and/or recanalization of portal veins. p value was calculated
for nding an association between source of drinking water and every histopathological nding on liver biopsy, and a signicant association was
found between source of drinking water as tap water and organizing thrombosis and/or recanalization of portal vein (p = 0.0416) which suggest that
source of drinking water might have an impact on the etiology of NCPF. Conclusion: Etiology of NCPF is possibly multifactorial. Tap water
(source of drinking water) could have a possible role in etiopathogenesis of NCPF, which needs to be further evaluated by case controlled studies.
ASSESSMENT OF BURDEN AND COPING MECHANISM OF CAREGIVERS OF PATIENTS ATTENDING PSYCHIATRIC OPD OF SELECTED HOSPITALS, WEST BENGAL.
Authors: Ghosh (Singh) Suparna , Maity Chandrima , Baisya Tapati
Published: September 2024

Introduction: WHO denes mental health as the state of wellbeing in which an individual realises his or her own capabilities can cope with the
normal stresses of life, can work productively and is able to make a contribution to his or her community. Caregivers of mentally ill person plays an
important role in the management of all mentally ill persons. They may be family or relatives of the patients. Aim: The aim of the study is to assess
the burden and coping mechanisms of caregivers of mentally ill clients and nd out the relationship among them. Method: A descriptive survey
research was conducted to assess burden and coping mechanisms of the caregivers of patients attending psychiatric outpatient department at
selected hospital, West Bengal. Total 170 caregivers of patients with mentally illness were selected by purposive sampling technique. Semistructured interview schedule, standardized Zarit Burden Interview Scale and Brief COPE Scale were used respectively to collect data. Result:The
ndings revealed that burden had statistically signicant strong negative (r = -0.95) correlation with coping mechanisms of caregivers. Total
58.82% caregivers had moderate level of burden whereas 61.18% caregivers adopted moderate level of coping. There was a signicant association
found between burden and age, gender, marital status, occupation and relationship with patients of the caregivers. Study results also showed that an
association was found between coping mechanisms and age and educational status of the caregiver. Conclusion: The ndings of the study showed
that majority of the caregivers felt moderate to severe burden and adopted moderate level of coping mechanism. This also helps the researcher to
come to some conclusions and preventive aspects of mental illness to provide for the possible suggestions and recommendations for future study
and expect the implication of the study in nursing eld.
NASAL DERMOID CYST: A CASE REPORT
Authors: Sneha Sneha
Published: September 2024

Congenital midline lesions of nose include nasal dermoids, encephaloceles and gliomas.The nasal dermoid is the least rare of these,
and is an uncommon midline developmental anomaly. Unlike other craniofacial dermoids which can present as a cyst, a sinus or a
stula(Setiyawan, 2013). In this patient it was a cystic nasal swelling obscuring vision without any problem in visual acuity. He had this
lesion from childhood but presented to Outpatient Department in adolescent age. Diagnostic nasal endoscopy , Ultrasonography, Fine
Needle Aspiration Cytology and Contrast Enhanced Computed Tomography of Nose and Paranasal sinuses were done reporting it as a nasal
dermoid without any bony erosions. All routine investigations were done and patient was planned for excision under General Anaesthesia.
Excision of the mass was done under General Anaesthesia and sent for Histopathology .HPE report conrmed it as a dermoid cyst .
A RARE PRESENTATION OF LOW-GRADE APPENDICEAL MUCINOUS NEOPLASM IN A ROUTINE APPENDICECTOMY SPECIMEN
Authors: Banik Sangeeta , Lilly S. Mary , Suresh Natarajan , Muddha Sai Sudha
Published: September 2024

Low grade appendiceal mucinous neoplasm (LAMN) is a rare malignancy which is mostly discovered incidentally and can present with a variety of
symptoms depending on the clinical manifestations. Due to an extensive accumulation of copious gelatinous material in the appendiceal lumen, the
appendix becomes cystically dilated. It can be detected on 0.7 to 1.7% of all appendicectomies. The most concerning side effect of this neoplasm is
mucin seeding, which might result in pseudomyxoma peritonei (PMP). Herein we report a 42-year-old female with lower abdominal pain
associated with nausea and regurgitation for 1 week. A clinical diagnosis of acute appendicitis was made and laparoscopic appendicectomy was
performed. Histopathological study of the appendix revealed a low grade appendiceal mucinous neoplasm.
EXTERNAL AUDITORY CANAL OSTEOMA WITH HIDDEN MIDDLE EAR CHOLESTEATOMA – A RARE CASE ASSOCIATION
Authors: Joy Josephine , R Jinoraj , A M Balasubramanya
Published: September 2024

Aim: Materials And Methods: To highlight a rare association of external auditory canal osteoma with middle ear cholesteatoma. 20-year-old
male, with right external auditory canal osteoma was treated surgically along with clearance of middle ear cholesteatoma at St. John's Medical
College Hospital, Bangalore, Karnataka, India. External auditory canal osteoma and middle ear choles Results: teatoma were approached via
posterior meatotomy with canaloplasty, tympanoplasty and epitympanotomy. Patient had signicant functional improvement following surgery
with no recurrence till date. While addressing external auditory canal osteoma, the possibilities of Conclusion: rare association of middle ear
cholesteatoma should be kept in mind and the surgeon should foresee the possibility of involvement of temporomandibular joint, facial nerve,
ossicular erosion and labyrinthine stula and thence, should be prepared to tackle any of the above situations appropriately.
UNSATISFACTORY ROOT CANAL TREATMENT AND LACK OF CONSOLIDATED BILL FOR REIMBURSEMENT: CONSUMER CASE AGAINST DENTIST: LESSONS TO BE LEARNT
Authors: Yadav Mukesh , Yadav Juhi
Published: September 2024

The Complainant, resides in Australia and underwent dental treatment by OP-2 Doctor at the OP-1 Hospital on 07.03.2014. On examination, OP-2
advised root canal treatment (RCT) and a dental cap for the damaged teeth. Accordingly, the OPs received various payments on different dates from
her. However, the OPs failed to provide a consolidated bill even after the treatment was completed on 27.03.2014, causing her parents to visit the
OPs Hospital multiple times. Consequently, her father, who was a bank employee was unable to get reimbursement of treatment cost. Also, OPs did
not properly treat her, necessitating further dental treatment in Australia, including capping costing. This OPs conduct constituted deciency in
service and unfair trade practice. Being aggrieved, she, through her mother and attorney holder Mrs. Kavita Sharma, led case in the District
Forum, seeking compensation for the treatment expenses along with litigation costs.The District Forum vide Order dated 22.10.2018 allowed the
complaint, nding the OPs liable for deciency in service and unfair trade practices in treating the complainant. The Forum directed the OPs to pay
towards treatment expenses along with interest at 9% per annum. Additionally, she was awarded as compensation for harassment and litigation
costs. However, on Appeal, the State Commission overturned this decision, concluding that there was no evidence of negligence on the part of the
Respondents. NCDRC disposing of Revision Petition observed that undisputedly, the Complainant underwent dental treatment at the OPs hospital,
including root canal treatment (RCT) and dental crown. However, issues arose regarding the treatment process, billing and subsequent dental care.
Additionally, there were concerns regarding consolidated bill and difculties in obtaining reimbursement from the Complainant's employer, a
bank.
ROLE OF COMPUTED TOMOGRAPHY IN ASSESSMENT OF SOLID AND CYSTIC RENAL MASS
Authors: Deepakbhai Khachariya Nandani , Desai Purvi
Published: September 2024

The widespread use of cross-sectional imaging techniques has led to a signicant increase in the detection of small, often asymptomatic renal
masses. Over 50% of renal cell carcinomas (RCCs) are discovered incidentally through noninvasive imaging methods. Effective management of
these renal masses requires a thorough understanding of imaging modalities to ensure accurate diagnosis, staging, and treatment planning. This
review examines the role of computed tomography (CT), in the evaluation of renal masses.
A STUDY ON INDUCIBLE CLINDAMYCIN RESISTANCE AMONG MRSA ISOLATES FROM THE CLINICAL SAMPLES IN A TERTIARY CARE HOSPITAL , WARANGAL.
Authors: Srujana Ravula , Sreedevi S. , G. M Sathishkumar.
Published: September 2024

Introduction: Staphylococcus aureus is one of the most common human pathogens capable of causing a wide range of infections, which are
hospital acquired as well as community acquired. Increasing incidence of methicillin resistance among staphylococci has led to usage of
macrolide-lincosamide-streptogramin B (MLSB) antibiotics to treat S.aureus infections, with clindamycin being the preferable agent owing to its
excellent pharmacokinetic properties. Inducible clindamycin resistance may lead to therapeutic failure. Aim And Objectives: To detect the
prevalence of constitutive and inducible clindamycin resistance in clinical isolates of methicillin resistance staphylococcus aureus (MRSA) by Dtest method to improve the clinical outcomes in patients. Materials And Methods: This is a prospective study done in a total of 120 MRSA isolates
obtained from different clinical samples. Methicillin resistance was detected using cefoxitin disc-diffusion method. D-test will be performed by
Kirby-bauer disc diffusion method using Mueller-Hinton agar (MHA) according to standard CLSI guidelines. Results: Out of 120 MRSA isolates,
108 shows erythromycin resistance and 96 shows clindamycin sensitive. Among erythromycin resistant isolates 11% showed constitutive
resistance (MLSB ), 26% showed inducible clindamycin resistance (MLSB ) 63% showed MS phenotype. The frequency of C i Conclusion:
constitutive and inducible clindamycin resistance in MRSA isolates emphasizes that D-test is very important and it must be included as routine
antimicrobial sensitivity test in diagnostic laboratories.
THE EFFECT OF FLUORIDE RELEASING BONDING AGENT ON MECHANICAL PROPERTIES OF ENAMEL- AN IN VITRO STUDY
Authors: Sharma Tanu , Puri Amrita , Singla Anshul
Published: September 2024

Aim- To evaluate the effect of uoride releasing bonding agent on mechanical properties of enamel. Material And Method- 44 extracted premolar
teeth free of any caries or pathology were taken and sliced in their long axis. The samples were equally divided into 4 groups- group 1: control
group, group 2: Transbond XT, group 3 : Orthosolo, group 4: Rely A Bond. After keeping the samples in remineralising solution for 40 hours the
hardness and roughness of the samples were tested by Vickers hardness testing machine and TIME 3200 roughness tester. Following this the
samples were treated with their respective group's bonding agent and kept in demineralizing solution for 96 hours. The hardness and roughness
were again measured and the results were statistically analysed. Result- The study revealed a signicant decrease in hardness and increase in
surface roughness across all groups after exposure to a demineralizing solution. The Control Group showed the greatest decrease in hardness, while
the Orthosolo Group displayed the least, indicating its resistance. Ortho Solo also exhibited the least increase in surface roughness. Transbond XT
and Rely A bond groups differed signicantly from the Control Group, suggesting their effectiveness in maintaining enamel properties. No
signicant difference was found between the Control Group and Transbond XT in hardness after exposure. Orthosolo and Rely A bond groups
showed superiority in preserving enamel hardness. Conclusion: Orthosolo, outperformed others in maintaining enamel hardness and surface
roughness. Transbond XTand Rely Abond also showed promise in preserving enamel mechanical properties.
RARE PRESENTATION OF SINONASAL MASS: EXTRA-NODAL ROSAI DORFMAN DISEASE: A CASE REPORT
Authors: U. Sathe Nilam , Taku Anjali , Gupta Davish , Chourdiya Monal
Published: September 2024

Introduction: Rosai -Dorfman disease (RDD) is a rare, usually self-limiting, benign condition which is characterised by over production and
accumulation of a histiocytes in the lymph nodes resulting in painless cervical lymphadenopathy. Extra -nodal RDD is uncommon and have been
reported in approximately 43 % of cases and can affects skin, respiratory tract, a solitary bone, nasal cavity, or the central nervous system.
Histopathological examination plays an important role in diagnosis which shows emperipolesis. Denitive treatment yet to established due to its
rarity and propensity for spontaneous remission. We reported a case of extra-nodal RDD involving the Case report: sinonasal area with
intracranial extension without lymphadenopathy in a 55 years old male who presented with complaint of nasal obstruction with difculty nasal
breathing and later was diagnosed of Rosai Dorfman disease on histopathological examination. Patient was managed by surgical excision and
adjuvant treatment with oral steroid and methotrexate. Due to lack of pathognomonic clinical and rad Conclusion: iological diagnostic features it is
difcult to diagnose RDD involving sinonasal area hence it is important to keep RDD as one of differential diagnosis in benign sinonasal mass.
Histopathology examination plays a very important role in denitive diagnosis of RDD. Surgical intervention is only recommended when there is
cosmetic deformities and obstructive symptoms. Long-term follow up is necessary to recognise and prevent the recurrences of disease.
ATYPICAL MYXOMA: CASE STUDY OF A RARE PARASPINAL TUMOR
Authors: Gautam Abhishek , Veerbhadrayya Mathapathi Siddalingeshwar , Maste Praful Suresh , Parajiya Ram
Published: September 2024

Myxoma is a neoplasm of mesenchymal origin composed of undifferentiated stellate cells in the myxoid stroma. Only eight cases of these benign
tumors involving the paraspinal muscles were reported in literature. We report the ninth case of intramuscular myxoma in the paraspinal
musculature. A 57-year-old male presented with progressively increasing painful swelling in the left paraspinal region. Imaging revealed
involvement of erector spinae muscle. The tumor was resected and sent for histopathological examination which revealed atypical intramuscular
myxoma. Follow-up at 1 year showed complete resolution of preoperative symptoms and no evidence of local recurrence. Although rare,
intramuscular myxoma should be included in differential diagnosis of paraspinal masses.
PATHOLOGICAL EVALUATION OF RESPONSE TO NEOADJUVANT CHEMOTHERAPY IN BREAST CANCER
Authors: Sanjay Desai Payal , Bhamra Swarneet , Bambora Quresh , Agrawal Preeti , Mehta Garima
Published: September 2024

Background:Breast cancer is globally known to be the most commonly diagnosed cancer in women. Among various modes of advanced therapies
available surgery remains the prime modality aided by chemotherapy, hormonal therapy and radiation. With the increasing use of neoadjuvant
chemotherapy for breast conservation, it becomes necessary for a pathologist to have the thorough knowledge of possible changes rendered by the
therapy. Aim: To assess the tumor and lymph node response in breast carcinoma after paclitaxel based chemotherapy. Settings and Designs : A
Cross sectional study carried out in the Histology section of Pathology department in American International Institute of Medical Sciences,
Udaipur. Methods: Study was conducted over the period of 4.5 years from January 2019 to May 2023. Clinical and tumor characteristics of
patients with breast carcinoma (n=47) were assessed preoperatively. Post- NACT breast cancer specimens (modied radical mastectomy and
breast conservation surgery) received in the histopathology section of our institute were analysed grossly and slides were prepared. The response in
tumor and lymph node was graded into pathological complete response (pCR), pathological partial response (pPR), and pathological no response
(pNR). Statistical Analysis: Statistical analysis was done using Pearson's Chi square test. Results: Our studies showed a pCR of 23.4% , pPR of
70.2% and pNR of 6.4%. Clinically small sized tumors (2–5 cms) showed a pCR of 6.0% (p value 0.001). Mean age at presentation was 49.9 yrs.
97.8 % of cases were invasive ductal carcinoma NOS of which 23.9% cases showed complete response (p value <0.001) . Only 2.1% of the cases
were mucinous carcinoma and all of them showed partial response. Ductal carcinoma in situ and lymphovascular invasion were found to be
resistant to chemotherapy (p value 0.015). Conclusion: The study concludes that histopathology is a gold standard method to assess the
chemotherapeutic tumor response. Tumor grades can be downgraded after neoadjuvant chemotherapy
INCIDENTAL FINDING OF PALATAL FOREIGN BODY OF AN INFANT- A CASE REPORT AND REVIEW OF LITERATURE
Authors: Ray Debasmita , Kar Tamal , Ray Amit , Sarkar Avishek De
Published: September 2024

Context :Foreign body in palate is very much common in infants and children. In case of infants, negative pressure from pacier use, thumb
sucking, breast feeding and characteristic texture of the child's palate can cause adhesion of the foreign object to the roof of the mouth. In case of
children, they are naturally curious and explore their environment using their hands and mouths. These objects can clinically resemble more serious
oral pathologies such as neoplasia or chronic inammatory conditions. There are several literatures have been reported predominately by dentists,
oral surgeons and paediatricians in the worldwide. The aim of this case report was to describe a rar Aim : e case of foreign body in the palate of an
infant and to highlight the thorough clinical examination in an uncooperative child and foreign bodies must be considered in the differential
diagnosis of palatal lesions found in children because unique foreign body and its position in the oral cavity made this diagnosis more difcult.
Conclusion : A clinical examination is utmost important, often can be done under anesthesia, if necessary, before a diagnosis is reached.
ADOLESCENTES EM CONFLITO COM A LEI
Authors: Araújo Marcos Venicios Andrade de
Published: September 2024

A adolescência é um período onde são criados valores, como também são apegados os costumes, construindo-se o caráter e as estruturas cognitivas, mas que ainda estão em formação. Isso implica dizer que o amadurecimento ainda é um pouco demorado e, assim sendo, o controle das emoções e tomada de decisões requer um espaço temporal e, a depender da construção familiar e da questão socioeconômica, boa ou ruim, está diretamente relacionada. Diante dessa questão, implica dizer que em países ou regiões onde a questão socioeconômica é precária, há naturalmente deslizes no contexto do desenvolvimento da criança e do adolescente na sua essência educacional e cultural, caso típico, que ocorre em países da América Latina. Nessa pesquisa se buscou demonstrar objetivamente, as incertezas no que se refere à vida do adolescente em conflito com a lei, sujeitos estes que, apesar de terem sofrido a dura responsabilização pela infração perpetrada, mesmo assim é um sujeito de direitos que tem a seu favor a garantia dos seus direitos fundamentais independente de escolhas feitas durante a vida. Pode-se demonstrar, através dos resultados alcançados, muito embora se verifique que as políticas públicas implementadas para o social sejam pouco eficientes, não só em países subdesenvolvidos, mas em muitos países tidos como desenvolvidos, sendo interessante entender que a opressão e a punição dos criminosos deveriam, na verdade, prepará-los para a reintegração por meio de atividades educativas e de tratamento, pois é impossível pensar na recuperação dos talentos dos indivíduos e o potencial de interação social, enquanto o mesmo fica preso sem o mínimo de observância de condições dignas.
Tratamento de Onicomicose por Terapia Fotodinâmica
Authors: Cristina Bueno da Costa Nunes Ariane , Savi Daiani
Published: September 2024

A terapia fotodinâmica (TFD) é uma técnica que utiliza um aparelho emissor de luz e um agente químico fotossensibilizante (FS) para tratar doenças causadas por microrganismo, como fungos, bactérias e vírus. Diversos estudos vêm sendo realizados e sugerem que a TFD pode ser uma alternativa eficiente no tratamento de onicomicose. Com base nesses dados, realizamos uma revisão da literatura sobre onicomicose e a resposta ao tratamento baseado na TFD. Para isso foi realizado uma busca na literatura utilizando os descritores: onicomicoses, terapia fotodinâmica, LED, lazer, azul de metileno ou fotossensibilizante, com o intervalo de tempo de 2014-2024. Os estudos demonstraram a eficiência da TFD no tratamento de onicomicose causadas por diferentes patógenos, sendo essa uma alternativa a utilização de antifúngicos. Entretanto são diversas as fontes de luz e FS avaliados para aplicação da terapêutica. Sendo que, a fonte de luz mais utilizada foi o LED associado ao azul de metileno, os quais demonstraram em todos os artigos selecionados ação antifúngica considerável, diminuindo ou mesmo eliminando o patógeno. Outras fontes de luz utilizadas foram LASER (Amplificação de Luz por Emissão de Radiação), tanto de baixa (LBI) quanto de alta intensidade (LAI), no entanto o LBI não mostrou resultados satisfatório quando comparado ao LAI e ao LED. Assim, a TFD é um método efetivo para o controle e tratamento de onicomicoses, no entanto seu resultado é dependente do grau da patologia, do fotossensibilizante e da fonte de luz utilizada.
Managing the Teaching Activity of Natural Science Subjects in Grade 6 at Secondary Schools in Bien Hoa City, Dong Nai Province
Authors: Dang Oanh Kieu Thi
Published: September 2024

Improving the quality of teaching natural science for grade 6 pupils, according to the 2018 General Education Program at secondary schools, is mandatory. Management activities are necessary to improve the quality of teaching. The tasks and purposes of this study are to analyze and evaluate the current status of management activities, find out the limitations and causes of the limitations, thereby proposing management measures to improve the quality of teaching Natural Science in grade 6 according to the 2018 General Education Program at secondary schools in Bien Hoa city, Dong Nai province. This study conducted a survey of 114 people including 20 board of directors, management staff, and 94 teachers of secondary schools according to the following contents: (i) Survey on awareness; (ii) Survey on planning; (iii) Survey on organizing teaching activities; (iv) Survey on directing teaching activities; (v) Survey on testing and evaluating teaching activities. The survey, combined with qualitative research, helps to correctly assess the current situation, limitations, and causes of limitations, which is the basis for perfecting management measures to improve the quality of teaching Natural Sciences for grade 6 according to the 2018 General Education Program at secondary schools, thereby contributing to the comprehensive development of educational quality and pupil capacity in Bien Hoa city, Dong Nai province.