bluuebunny/crossref_metadata_2025 huggingface dataset:
PREPARASI DAN KARAKTERISASI SUBMIKRO PARTIKEL KITOSAN DAN NATRIUM ALGINAT SEBAGAI PEMBAWA CAPTOPRIL DENGAN VARIASI KITOSAN
Authors: Wahyuni Yenni Sri , Melinda Risya , Rasyad Ade Arinia
Published: December 2022

Telah dilakukan penelitian mengenai submikro partikel kitosan dan natrium alginat sebagai pembawa kaptopril. Penelitian ini bertujuan untuk mengatasi permasalahan permeabilitas dan memperbaiki absorbsi suatu senyawa makromolekul. Preparasi kaptopril menjadi submikro pertikel dengan polimer penjerap kitosan, natrium alginat dan crosslinking CaCl2 dengan metode gelasi ionik dapat memperbaiki masalah permeabilitas kaptopril. Konsentrasi kitosan yang divariasikan terhadap formula F1, F2 dan F3 berturut-turut adalah 0,1%; 0,2% dan 0,3% menghasilkan persen entrapment efficiency (EE) masing-masing sebesar 69,69%; 76,86% dan 79,2%, distribusi partikel (PDI) dan zeta potensial yaitu 232,0 nm; 0,259; -29,1 mV (F1), 333,8 nm; 0,290; +32,4 mV (F2), dan 426,3 nm; 0,321; +55,6 mV (F3).  Formula submikro partikel dapat diperoleh pada formula 3 (kitosan 0,3%). Konsentrasi polimer mempunyai pengaruh penting terhadap persen entrapment efficiency (EE), ukuran pertikel, distribusi partikel, dan zeta potensial dari submikro partikel captopril.
Industrial Internet of Things – An Overview
Authors: C. Sailaja
Published: December 2022

Internet of Things (IoT) is a network of intelligent objects (smart sensors) that are connected and accessible to the Internet through devices such as routers to exchange data. Many useful applications can be developed using IoT. IoT has brought a change in such a way that everything around us can be turned into smart devices e.g., smart cars, smart homes, smart parking, smart cities etc., thereby connecting human, machine & things seamlessly. The advent of cheaper processing power, communication cost and some marketing have created the IoT of today. When the principles of IoT are applied to Industries, it is termed as Industrial IoT. Smart sensors and Industrial Internet of Things (IIoT) are modern tools which drive Industry 4.0. The use of smart sensors and IIoT have a positive impact in enhancing the quality & value of products and improve efficiency. The combination of smart sensors with its processing & networking capabilities help in transferring the process data to the centralized database for further analysis. Thus, digitalization has helped industry to reimage the business with the transformation brought about by IIoT. This paper discusses some of the applications of IIoT such as Remote Monitoring & Service, AI & ML based predictive analysis and Closed loop Digital twin using IoT sensors.
DESENVOLVIMENTO E APLICAÇÃO DE REDE NEURAL CONVOLUCIONAL PARA O DIAGNÓSTICO DE OSTEOARTRITE DE JOELHO
Authors: Sílio Luís Felipe , Passos Ricardo Pablo , Oliveira José Ricardo Lourenço , Fileni Carlos Henrique Prevital , Pereira Adriano de Almeida , Fonseca Neto Victor Marques da , Rodrigues Marcelo Francisco , Lima Bráulio Nascimento , Vilela Junior Guanis de Barros
Published: December 2022

INTRODUÇÃO: a osteoartrite do joelho (OA) é uma doença articular degenerativa, que ocasiona desgaste e perda progressiva da cartilagem local. Os sintomas de OA incluem rigidez, mobilidade articular limitada e presença de dor que podem levar a uma diminuição na qualidade de vida e comprometimento da saúde. A interpretação/análise clínica de imagens suporta um trabalho cada vez maior nos centros ortopédicos e de radiologia. O presente estudo desenvolveu e aplicou o desempenho de uma rede neural convolucional projetada para auxiliar ortopedistas e radiologistas na detecção e classificação de osteoartrite do joelho de graus iniciais a severos, de acordo com o sistema de classificação Kellgren-Lawrence (KL). OBJETIVO: Desenvolver e validar uma CNN capaz de classificar e diagnosticar a OA no joelho de forma dinâmica e eficaz. Material e métodos: Utilizou-se uma pesquisa descritiva de caráter quali quantitativo e métodos da IA aplicados na análise do movimento humano. Foi utilizado um banco de dados com radiografias de OA de joelho (Grau 0 - 3.085 imagens, Grau 1 - 1.416 imagens, Grau 2 - 2.062 imagens, Grau 3 - 1.029 imagens e Grau 4 - 236 imagens). Para análise e classificação das imagens foi utilizado um ambiente de desenvolvimento da linguagem Python, por meio da aplicação Google Colab executada via browser. As imagens foram utilizadas para treinar um conjunto de arquiteturas de rede neural para a previsão do nível de gravidade, segundo a classificação de KL em OA. RESULTADOS: em seguida da configuração da CNN, iniciou-se o treinamento de máquina com as radiografias, em seguida realizados testes e por fim a integração, obtendo-se uma classificação expressa com as de taxas de sensibilidade de teste com a densidade de rede com joelho saudável, OA leve, moderado e grave. Após a classificação e análise das imagens na rede convolucional, foi gerado o comportamento do classificador sobre a precisão do algoritmo na exatidão do diagnóstico. O algoritmo apresentou acurácia de 0,85 (OA mínimo), 0,79 ( joelho saudável), 0,89 (OA moderado) e 0,98 (OA severo. Precisão de 0,67 (joelho saudável), 0,71 (OA mínimo), 0,86 (OA moderado) e 0,82 (OA severo). Sensibilidade de 0,65 (joelho saudável), 0,77 (OA mínimo), 0,79 (OA moderado) e 0,93 (OA severo). Especificidade de 0,86 (joelho saudável), 0,88 (OA mínimo), 0,94 (OA moderado) e 0,93 (OA severo). CONCLUSÃO: Nossos modelos de aprendizagem profunda propostos forneceram alta precisão e acurácia satisfatória para a detecção e classificação de osteoartrite leve ao severo do joelho em radiografias simples. Esses modelos podem ser usados como auxílio no diagnóstico clínico de radiografias de joelho e na orientação do tratamento em cada estágio da patologia para médicos, radiologistas e profissionais do movimento humano.
EFEKTIVITAS PENGGUNAAN ONLINE DICTIONARY SEBAGAI MEDIA PEMBELAJARAN PENERJEMAHAN
Authors: Anak Agung Istri Yudhi Pramawati
Published: December 2022

Penerjemahan saat ini sangat terbantu oleh hadirnya teknologi penerjemahan, baik mesin penerjemah otomatis maupun kamus online. Mesin-mesin penerjemah otomatis dapat dikatakan sangat mempermudah proses penerjemahan dengan fitur data base yang digunakan. Selain mesin penerjemah otomatis, kehadiran online dictionary pun sangat membantu dalam proses penerjemahan, terutama dalam proses pembelajarannya. Seringkali, mahasiswa beranggapan bahwa proses penerjemahan adalah proses yang sulit dan memakan waktu karena harus berhadapan dengan kamus manual. Penelitian ini bertujuan untuk mendeskripsikan penggunaan online dictionary dalam membantu mahasiswa dalam pembelajaran penerjemahan. Metode penelitian yang digunakan yaitu deskriptif kualitatif dimana data-data kualitatif dijabarkan secara deskriptif. Data dikumpulkan melalui tes dan wawancara. Hasil menunjukkan bahwa penggunaan online dictionary sangat membantu mahasiswa dalam pembelajaran penerjemahan walaupun memeiliki kendala dalam penggunaannya. Kesalahan penerjemahan yang kerap dilakukan mahasiswa mencakup kesalahan leksikal dan kesalahan gramatikal.
KEPRAKTISAN SOAL PEMODELAN MATEMATIKA MENGGUNAKAN KONTEKS BIAYA PARKIR
Authors: Bambang Riyanto
Published: December 2022

Tujuan penelitian ini adalah menghasilkan soal pemodelan matematika yang praktis menggunakan konteks biaya parkir untuk pembelajaran matematika. Penelitian ini menggunakan penelitian pengembangan yang menghasilkan soal pemodelan matematika dengan konteks biaya parkir yang praktis untuk pembelajaran matematika. Pendekatan dalam penelitian ini adalah design research, yaitu jenis studi pengembangan yang terdiri dari pendahuluan, prototipe, dan penilaian. Penilaian yang diterapkan pada fase prototyping adalah studi formatif, meliputi fase evaluasi diri, fase expert review dan fase one-to-one, small group dan field test. Pada artikel ini, pembahasan hasil berada pada fase small group. Pengumpulan data dilakukan dengan dokumentasi dan wawancara. Berdasarkan hasil analisis data, peneliti dapat menyimpulkan bahwa penelitian ini telah menghasilkan tugas pemodelan matematika dengan konteks biaya parkir untuk pembelajaran matematika tahap pengembangan yang praktis untuk pembelajaran matematika.
HAMBATAN-HAMBATAN YANG DIALAMI MAHASISWA DALAM PEMBELAJARAN DARING SELAMA PANDEMI COVID-19
Authors: Kolivia  , Nazaryo Radja  , Kelik Wachyudi  , Acep Bahrum Kamil
Published: December 2022

Pandemi Covid-19 telah memberikan perubahan yang signifikan pada proses belajar dan mengajar. Dengan memperhatikan dampak tersebut maka penelitian ini membahas mengenai hambatan-hambatan yang dialami mahasiswa selama pembelajaran daring.  Tujuan penelitian ini adalah untuk menginvetigasi kendala yang selama ini ditemukan selama kegiatan pembelajaran berlangsung. Metode yang diguanakan adalah studi pustaka. Pengumpulan data diperoleh dari artikel penelitian sebelumnya, peneliti mencari artikel yang relevan dengan permasalahan yang sedang diteliti. Teknik analisis data yang digunakan adalah dengan reduksi data, display data, dan penarikan verifikasi kesimpulan. Hasil penelitian menunjukan bahwa terdapat tiga hambatan yaitu: 1) sarana prasarana atau fasilitas yang kurang memadai, 2) kesulitan mahasiswa dalam memahami materi, dan 3) keterbatasan kemampuan dosen dalam memanfaatkan teknologi.
ANALISIS KESALAHAN SISWA DALAM MENGERJAKAN SOAL CERITA POKOK BAHASAN ALJABAR BERDASARKAN PROSEDUR NEWMAN
Authors: Putu Reynaldy Artha Nugraha  , Kadek Rahayu Puspadewi  , Kadek Adi Wibawa
Published: December 2022

Penelitian ini merupakan penelitian deskriptif kualitatif yang bertujuan untuk mengetahui jenis kesalahan serta penyebab kesalahan yang dilakukan siswa dalam mengerjakan soal cerita matematika. Instrumen penelitian yang digunakan berupa tes esai dan lembar wawancara. Sebanyak 30 orang siswa kelas VII H SMP (SLUB) Saraswati 1 Denpasar menjadi subjek penelitian ini. Metode purposive sampling digunakan untuk selanjutnya memilih 6 subjek untuk diwawancara. Hasil penelitian menunjukkan bahwa kesalahan yang dialami oleh kelompok tinggi terbanyak terjadi pada tahap penulisan jawaban akhir, kelompok sedang terbanyak pada tahap transformasi dan keterampilan proses, sedangkan kelompok rendah pada tahap transformasi. Penyebab kesalahan yang terjadi adalah (1) kurang memahami soal dengan baik, (2) kurang hati-hati dalam membaca soal (3) kurang teliti dalam menghitung, (4) terburu-buru dalam mengerjakan soal, dan (5) kurang bisa mengelola waktu dengan baik saat mengerjakan soal.
CORRELATION BETWEEN VOCABULARY MASTERY AND READING COMPREHENSION OF EIGHTH-GRADE STUDENTS OF SMP TP. 45 DENPASAR
Authors: Wensislaus Sunardi Woga  , Putri Wirastuti I Gusti Agung , Krismayani Ni Wayan
Published: December 2022

This study aims to clarify the relationship between vocabulary acquisition and reading comprehension. This study is a correlation study. Samples are selected using a random sampling technique and consist of 30 students. To collect the data, the researchers also used two types of tests. Fill in the blanks for the vocabulary proficiency test and the short answer reading comprehension test. In addition, the data collected were analyzed using the SPSS 20.0 program. The results of the paired sample t-test are bilateral significant values ​​from the student's vocabulary and reading comprehension  010. The results showed that the variances of the significance values ​​of the t-test were relatively equal due to the greater significance. From 0.05. The result of calculating the correlation between the student's vocabulary and reading comprehension in reading comprehension was r = 813. From the results, it can be concluded that there is a significant correlation between vocabulary and reading comprehension in the 8th-grade students of SMP TP.45 Denpasar in 2021/2022.
PERUBAHAN KONSEPTUAL MELALUI PENERAPAN LABORATORIUM VIRTUAL DAN KAJIAN WEDA PADA MAHASISWA
Authors: Gusti Ayu Dewi Setiawati  , Kadek Yudista Witraguna
Published: December 2022

Penelitian ini bertujuan untuk mengetahui pola perubahan konseptual dalam pembelajaran melalui penerapan laboratorium virtual dan kajian Weda serta untuk mengetahui dampak penerapan terhadap perubahan konseptual. Penelitian ini dilakukan karena rendahnya hasil belajar IPA yang diakibatkan oleh kurangnya penguasaan konsep ilmiah mahasiswa. Variatifnya respon jawaban uraian menunjukkan mahasiswa cenderung mengalami miskonsepsi. Penelitian ini merupakan penelitian deskriptif kualitatif. Subyek penelitian adalah 45 orang mahasiswa semester IV pada Jurusan Pendidikan Guru Sekolah Dasar (PGSD) UHN I Gusti Bagus Sugriwa Denpasar. Instrumen yang digunakan untuk mengetahui perubahan konseptual pada sebelum dan sesudah perlakuan berupa tes tertulis berbentuk pilihan ganda beralasan dan dipadukan dengan metode Certainty of Response Index (CRI). Data berupa jawaban dari tes tersebut kemudian dianalisis secara kualitatif dengan Model Miles & Huberman. Hasil analisis menunjukkan bahwa terjadi perubahan konseptual pada mahasiswa. Pola perubahan konseptual mahasiswa yaitu berubah positif, berubah negatif, bertahan positif dan bertahan negatif. Rata-rata tertinggi terdapat pada pola konsepsi IV yaitu sebesar 60,85%. Selain itu, miskonsepsi mengalami penurunan sebesar 43,75%. Penerapan laboratorium virtual dan kajian Weda merupakan suatu inovasi proses pembelajaran yang memberikan dampak positif bagi perubahan konseptual.
IMPLEMENTASI GERAKAN LITERASI SEKOLAH (GLS) PADA PEMBEJARAN JARAK JAUH DI SD NEGERI 26 PEMECUTAN
Authors: Ni Nyoman Tri Wahyuni  , Putu Suweka Oka Sugiharta  , I Wayan Eka Biasa
Published: December 2022

Penelitian ini bertujuan untuk mengetahui implementasi Gerakan Literasi Sekolah (GLS) yang dilaksanakan di SD Negeri 26 Pemecutan pada saat pembelajaran jarak jauh dengan menggunakan pendekatan deskriptif kualitatif. Data ini dikumpulkan dengan teknik observasi non partisipan, wawancara tak terstruktur, angket tertutup, dan kuisioner terbuka. Pandemi Covid-19 menyebabkan kegiatan pembelajaran tidak dapat dilaksanakan secara tatap muka, kegiatan pembelajaran dilaksanakan jarak jauh. Demikian pula pelaksanaan Gerakan Literasi Sekolah (GLS) tidak dapat dilaksanakan seperti biasanya. Di SD Negeri 26 Pemecutan sebelumnya dilaksanakan kegiatan literasi dengan kegiatan membaca 15 menit sebelum pembelajaran dimulai serta kunjungan rutin ke perpustakaan seminggu sekali, namun pada pembelajaran jarak juah tidak dapat dilaksanakan kegiatan-kegiatan tersebut.  Pada saat pembelajaran jarak jauh Gerakan Literasi Sekolah (GLS) di SD Negeri 12 Pemecutan dilaksanakan dengan berbagai kegiatan seperti literasi di awal pembelajaran, pelatihan membaca nyaring untuk siswa, orang tua, dan guru, guru melakukan apersepsi, sekolah aktif dalam kegiatan festival literasi sekolah serta peserta didik membuat video bercerita. Kegiatan ini diharapakan dapat meningkatkan kemampuan literasi peserta didik meskipun dilaksanakan secara jauk jauh.
Teatry żydowskie w Warszawie między wojnami (1918–1939)
Authors: Krasiński Edward
Published: December 2022

W 1837 roku działał w Warszawie teatr Dawida Hellina, co można uznać za początek teatru żydowskiego w Warszawie, chociaż jego rozkwit  nastąpił dopiero pod koniec XIX wieku. Ester Rachel i Abraham Kamińscy stworzyli wówczas stały zawodowy zespół, a w 1913 otworzyli własną siedzibę – teatr, którego tradycję kontynuowała ich córka, Ida. W artykule omówione zostały najważniejsze przedstawienia teatrów żydowskich, ich repertuar, warunki techniczne i finansowe, a także źródła archiwalne i prasowe do badania historii teatru żydowskiego w Warszawie przed II wojną światową. Trupa Wileńska i Warszawski Żydowski Teatr Artystyczny WIKT miały w repertuarze sztuki ambitne, klasykę żydowską i współczesny dramat światowy. Michał Weichert prowadził eksperymentalny Jung Teater o ambicjach politycznych. Powstawały liczne, choć działające krótko, teatry miniatur, sceny rewiowe i kabaretowe. Większość teatrów jidysz sąsiadowała z polskimi, ale działały też teatry w dzielnicy żydowskiej, jak Centralny czy Scala. Związki między teatrem polskim i żydowskim należy rozpatrywać wielostronnie, w odniesieniu do publiczności, repertuaru i krytyki, a także współpracy między teatrami i twórcami.
«Rozsiani i rozrzuceni» («Cezejt un ceszprejt») Szolem Alejchema w Warszawie (1905 i 1910)
Authors: Szmeruk Chone
Published: December 2022

Historia zapomnianej sztuki Szolema Alejchema Rozsiani i rozrzuceni, która od publikacji w tygodniku Jidisze Folkscajtung (1903) i realizacji na scenach teatrów od Kowla do Nowego Jorku (1903–1905) była uznawana za odzwierciedlenie aktualnych prądów społecznych, narodowych i kulturowych. Społeczność żydowska przyjęła ją entuzjastycznie. Grano ją w języku jidysz, po polsku, rosyjsku i hebrajsku na scenach zawodowych i amatorskich. Po pierwszej wojnie światowej zniknęła z repertuarów. Miała kilka wersji autorskich. Jej tematem jest konflikt pokoleniowy między rodzicami a dziećmi, które po przeprowadzce rodziny z małego do dużego miasta zbyt szybko ulegają wielkomiejskim pokusom i angażują się w działalność polityczną. Rodzina się rozpada, komedia przekształca się w tragikomedię. Recepcja sztuki zostaje szeroko omówiona również w kontekście kontaktów między warszawskimi Żydami a polskim teatrem.
Summary
Authors: Prussak Maria
Published: December 2022

Summary of Pamiętnik Teatralny 1992/1-4. The first part includes an account of the long process of working on this volume, the initial concept of which was born in 1964, as well as a description of the various circumstances that either paralyzed or hindered its preparation. The second part contains a detailed discussion of the content of all the articles.
THE RELATIONSHIP BETWEEN HUSBAND'S KNOWLEDGE AND SUPPORT WITH PREGNANT WOMEN'S VISITS DURING THE COVID-19 PANDEMIC
Authors: Marlin W.M.Liem  , Afnani Toyibah  , Lisa Purbawaning Wulandari
Published: December 2022

The Visits of pregnant women are one of the important indicators for pregnant women during pregnancy. Regular ANC visits can detect early complications during pregnancy, so they can be treated early. Husband's knowledge and husband’s support for regular ANC visits, even during the Covid-19 pandemic, is very important to encourage pregnant women to regularly attend ANC visits. The purpose of this study was to determine the relationship between husband's knowledge and support and visits by pregnant women during the Covid-19 pandemic. The design used is an analytical survey with a cross sectional approach. A sample of 30 respondents with total sampling technique. The research instrument was the husband's knowledge and support questionnaire for the regularity of ANC visits by looking at the mother's MCH handbook. The research results obtained that knowledge is included in the good category, namely as many as 12 respondents (40%). Husband support, half of respondent which did not support, namely as many as 16 respondents (53.3%). Part of the regularity of visiting pregnant women is irregular, namely 17 respondents (56.7%). The results of data analysis using Spearman correlation rho value of r 0.020 with significance (p value) = 0.05. Conclusion: there is a significant relationship between knowledge and regularity of visiting pregnant women during the Covid 19 pandemic. It is hoped that husbands need to increase their knowledge and support to motivate pregnant women to visit ANC even during the Covid-19 pandemic
„Wspomnienia wygnanki” Pauliny Krakowowej – powieść dla dziewcząt i pierwsza polska „robinsonada”
Authors: Nosek Anna
Published: December 2022

The aim of this dissertation is to present the forgotten novel Wspomnienia wygnanki from 1844 by Paulina Krakowowa. The author draws attention to its readability and literary values, which made it a bestseller in the 19th century. The dissertation also offers an analysis and interpretation of Wspomnieniawygnanki in the context of nineteenth-century novels for girls, as well as in the context of adventure novels, the so-called “robinsonada”. This is because Krakowowa’s novel is saturated with sensational, adventure and travel themes. Therefore, it should be placed within and outside the circle of nineteenth-century novels for girls. Wspomnienia wygnanki is an innovative novel,going beyond the usual conventions of moral prose and novels of manners towards an adventure novel (“robinsonade”), which, in the nineteenth century, was reserved almost exclusively for boys.
Siła kobiet, moc fantastyki – po co są czarownice w powieści dla dziewcząt?
Authors: Zajkowska Joanna
Published: December 2022

The article discusses the five novels of contemporary Polish writer Marcin Szczygielski about a young witch – Maia. The figure of a witch, which has become an emblem of contemporary feminist movements, also appears in the works of fantasy literature, in which they function as emanations of the power of femininity. The young heroine of Szczygielski’s novel also functions on such a level. Building strong female characters in novels for girls is a new trend in this type of literature – and Szczygielski’s works about the adventures of a young witch are the best representation of this.
Korespondencja Ludwika Czarkowskiego z Janem Karłowiczem ze zbiorów Archiwum Historycznego w Wilnie
Authors: Rembiszewska Dorota , Trawińska Maria
Published: December 2022

The article includes five letters that Ludwik Czarkowski sent to Jan Karłowicz in 1890 and 1894. Czarkowski was a physician, combining his professional work with his ethnographic and bibliophilic interests. He actively participated in various organizations and scientific societies. He also collaborated with the Journal “Wisła”, whose editor was Jan Karłowicz. In the letters addressed to him, Czarkowsky deals primarily with ethnographic issues. He writes about the various dialect materials ha had collected, such as vocabulary, songs, proverbs and fairy tales. He also provides editorial comments on the articles published in “Wisła”. The letters are an important testimony documenting the 19th-century beginnings of ethnographic research.
Research Trend in Halal: A Bibliometric Analysis Using the Scopus Database
Authors: Nurunnajwa Siti Nurunnajwa Shamsudin , Abu Bakar Elistina , Osman Syuhaily , Mohd Dali Nuradli Ridzwan Shah , Anuar Musaddad Nusaibah
Published: December 2022

Halal research started in the early 2000s and has been growing since 2015 until now. As the halal industry keeps developing and expanding, more research is needed to contribute ideas and findings to improve the halal industry. This study aims to examine previous studies on halal and find the gaps for future research. A sample of 879 articles published in the Scopus database from 1997 to 2020 was analysed using bibliometric analysis. The authors used Microsoft Excel and VOSviewer software to study information about journals, articles, authors, citations, keywords, and countries. The analysis reveals halal research trends according to the publication, authors, countries, subject area, journals, and theme by the topics and abstracts. This study also exposes gaps in halal research and gives suggestions for future studies.
Anti-SARS-CoV-2 Biotherapeutics and Chemotherapeutics: An Insight into Product Specifications and Marketing Dynamics
Authors: Kotra Vijay , Mallem Dinakar , Kanuri Anil Kumar , Burra Mahesh Reddy , Nyamathullah Shaik , Ying Looi Shu , Husain Khairul Anwar , Varala Ravi , Sudhakar Madhadevi , Goh Khang Wen , Sam Toong Hai , Ming Long Chiau
Published: December 2022

Chemotherapeutics and biotherapeutics agents have been explored as a potential treatment for COVID-19. This study was aimed to elucidate latest update related to biotherapeutics and chemotherapeutics against COVID-19 and its variants as well as the product specifications and marketing dynamics of its pharmacotherapies. There are several chemotherapeutics that have been studied for the treatment of COVID-19, including Paxlovid (Nirmatrelvir & Ritonavir) fixed dose combination, nirmatrelvir and ritonavir fixed dose combination, Remdesivir (Vekulary/Covifor) fixed dose combination, chloroquine and hydroxychloroquine, molnupiravir, favipiravir, Infliximab (Remsima®) fixed dose combination tocilizumab (Actimera), casirivimab+imdevimab (Ronapreve) fixed dose combination, ivermectin, methylprednisole. These drugs have been repurposed for use in COVID-19 due to their antiviral properties and ability to reduce inflammation. The COVID-19 death cases have significantly reduced because of tested efficacy of advanced biotherapeutics and chemotherapeutics. As for marketing dynamics, the demand for chemotherapeutics for the treatment of COVID-19 has increased significantly since the outbreak of the pandemic. Hence, the prices of anti-viral and monoclonal antibodies in top COVID-19 affected countries is also presented here. Considering the molecular interactions, therapeutic activity, efficacy, and adverse effects, the USFDA and the WHO recommended the aforementioned drugs. The chances of approval seems favouring biotherapeutics as these have the best characteristics among the chemotherapeutics. Overall, this review contributes to the scientific understanding of the COVID-19. This can help to inform future research and development efforts and contribute to the overall advancement of knowledge in the field of medicine.
Planning, implementation and evaluation of enterprise resource management strategies
Authors: Matvieiev Pavlo
Published: December 2022

Introduction. The development of innovation strategy is carried out within the strategic management of the enterprise. The innovation strategy has a long-term character and is formed in accordance with the goals of the enterprise for the optimal redistribution of resources within the investment activity.
The purpose of the research is to summarize the theoretical and practical aspects of planning, implementation and evaluation of strategies for managing the resource potential of enterprises to develop recommendations in the field of agriculture.
Results. The conditions of implementation and content of strategic management are determined. Aspects are substantiated that influence the choice of innovation strategy of the enterprise. The importance of directions coordination of innovative activity within the enterprise is noted. The expediency of forming the concept of socio-economic adaptation of the agricultural enterprise to the innovative model of technological development is substantiated. The definition of "economic adaptation" is given. Restrictions are described that prevent the introduction of an innovative model of technological development in the activities of Ukrainian agricultural enterprises. The role of the quality of staff interaction is noted in the process of enterprise innovative development. The measures have been identified to eliminate the negative impact of the innovative model of technological development on enterprises in the agricultural sector. The application of the methodology of interests’ coordination in the development process of technical re-equipment projects at the agricultural enterprise is offered. The conceptual content and principles of socio-economic adaptation of the agricultural enterprise to the innovative model of technological development are characterized. It is proposed to determine the competitiveness of the enterprise as a result of its socio-economic adaptation. The main indicators for evaluating the result of such adaptation are described. The coordination role of enterprise subjects’ interests in the course of social and economic adaptation is noted.
Keywords: competition, resource potential, agricultural enterprise, adaptation, strategic management, strategy, innovative model of technological development.
Management of operations for the production and sale of products of agricultural enterprises, taking into account the risk
Authors: Patlatiuk Serhii
Published: December 2022

Introduction. A fundamental feature of economic activity of agricultural enterprises is the relationship of natural, biological, technological, organizational and social factors, which significantly exacerbates the risks that negatively affect the financial results and can reduce the competitiveness and financial stability of enterprises. Practice shows that today risk management is becoming an integral part of the strategic and operational management of successful agribusiness enterprises.
The purpose of this article is to develop theoretical and methodological provisions for risk management in the oper-ating system of agricultural enterprises.
Results. The stages of strategic management of operations taking into account risks at the agricultural enterprises are offered. Management strategies with risk taking into account at agricultural enterprises of plant specialization are substanti-ated. A hierarchical model has been developed for estimating the optimal structure of sown areas, gross harvest and sales of crop products, taking into account the avoidance of business risks. An assessment of strategies has been done for managing the production and sale of crop products, taking into account the risks for enterprises in different areas of Kyiv region.
Conclusions. The peculiarities of risk in the production and sale of agricultural products are defined, which are the relationship of the causes of their occurrence, namely: uncertainty of the future, lack of information, incompetence of man-agement and unpredictable behaviour of partners. A multilevel model of management production operations and sale of agricultural products taking into account risks is developed, which allows to recommend the heads of agricultural enterpris-es the optimal structure of sown areas, forecast gross harvest, average yield, as well as choose storage conditions and evaluate sales results.
Keywords: agricultural enterprises, risks, operations management, risk-based management strategies, strategy opti-mization.
Formation of organizational and economic conditions for the development of precision farming in Belarus
Authors: Borodinskaya Evgeniya , Radkovich Maryia
Published: December 2022

The purpose of this research is to study the experience of introducing precision farming technologies abroad and to substantiate the directions of development and practical implementation of these technologies in Belarus. The article discuss-es the leading countries in the field of practical testing of modern technologies of precision farming, analyzes the experience of their use in the EAEU countries, studies the developments in the main directions of the introduction of precision farming in Belarus: the use of GPS for determining field boundaries, remote sensing of the earth, mapping and monitoring the state of crops and productivity; technologies of differentiated application of seeds, fertilizers and pesticides, differentiated pre-sowing soil treatment; technology of parallel driving and automatic control over the work and movement of technical equipment. Based on the results of the analysis, such directions of development and practical use of precision farming tech-nologies in Belarus have been identified, such as the implementation of domestic industrial developments; development of domestic software and hardware; expanding scientific research on precision farming technologies; generalization and dis-semination of scientific and production experience in the introduction of precision farming; development of government measures to support commodity producers, including farms, mastering precision farming technologies.
The scientific novelty lies in the study of the problems of introducing precision farming technologies in Belarus, tak-ing into account world experience, as well as in developing priority areas for the further development of precision farming in Belarus.
The practical significance lies in the need to introduce precision farming technologies in agricultural organizations of Belarus.
It is advisable to continue the research in the direction of developing a methodology for assessing the degree of intro-duction of precision farming technologies, as well as a comprehensive analysis of the results of the practical use of these technologies at micro- and mesoscale levels.
Keywords: agriculture, efficiency, sustainability, innovative technologies, precision farming, world experience, de-velopment directions in the Republic of Belarus.
Wage of employees in the agricultural sector: modern socio-economic and accounting aspects
Authors: KRYUKOVA Iryna , Federka Tetyana
Published: December 2022

Introduction. Many socio-economic problems are characteristic of the agricultural sector, the main of which are: mi-gration of rural population, low income and quality of life of rural residents, lack of social infrastructure of the village, re-ducing the prestige of agricultural work for young professionals. Increasing the level of remuneration and income of the hired personnel of agrarian business entities is a prerequisite for solving such modern problems.
The purpose of the research is identification and analysis of modern socio-economic trends and problems of account-ing and analytical support in the field of remuneration of personnel of agrarian enterprises.
Results. A wage is one of the most important indicators of the level of socio-economic development of industries and regions. In the agrarian sector wage is traditionally one of the lowest among all sectors of the national economy. The share of wages of agricultural personnel is about 68% of the national average (UAH 7166). The range of wages in the industry by region is significant: the highest is in Ivano-Frankivsk and Kyiv and the lowest is in Odessa and Zaporizhye region. In the structure of agricultural production costs, the share of labor costs does not exceed 5-8%. The minimum wage in Ukraine is 58% of the lowest in the European Union.
The main problematic aspects of modern payroll accounting are: the practice of accounting for costs associated with agri-social responsibility programs, the lack of common practice of actuarial valuation methods, discounting the cost of future personnel costs, the imperfection of accounting policies, the order of accounting of the costs associated with the effec-tive mechanisms of agrarian labor stimulation, the limited forms of financial and statistical reporting financial indicators of employment.
Conclusions. Implementation of the results showed that the time required to pay the most hired to the personnel of the agrarian sector of Ukraine is significantly lower than the other types of economic practice and foreign practice. The main problematic socio-economic aspects of wages in the industry were identified: tendencies of regional agrarian labor markets, low social standards, low share of wage costs in their general structure, limited size of enterprises slow wage growth in the industry, lack of mechanisms incentives for work in most small agribusinesses. Further improvement of payroll accounting should occur as an informational and analytical supplement to agronomy management in the context of the implementation of modern value management concepts with a focus on human capital.
Keywords: wages, salaries, staff, agriculture, cost accounting, calculations with employees, analytical support, agri-cultural enterprises.
Dynamics of integrated indicators of the level of sustainability of the economy of Ukraine and agricultural com-plex in Ukraine
Authors: KOZAK Kateryna
Published: December 2022

Introduction. The current stage of socio-economic development demonstrates a change in worldview based on envi-ronmental and at the same time humanistic ethics. Accordingly, the assessment of the real state of the national economy, the development of effective state economic policy requires consideration not only of purely economic factors. The study of sus-tainable economic development on the basis of statistical indicators specified in macroeconomic, regional and sectoral indica-tors of ecological and economic development and quality of life indicators makes it possible to outline areas of sustainability, boundaries, which are a "corridor" of acceptable deviations from the unambiguous trajectory. The purpose of the article is to develop methodological principles for integrated assessment of the level of sustainability of economic development of Ukraine's economy and its agro-industrial sector. Results. The author's complex approach to estimating the level of sus-tainability in the territorial-sectoral context is proposed, which is based on the calculation of integrated indicators of eco-nomic, social, ecological, infrastructural blocks on the basis of rationing of initial indicators taking into account their stimu-lating and disincentive character by the arithmetic mean. Indicators of the economic block of sustainability of national level development are presented. The dynamics of integrated indicators of the sustainability level of Ukrainian economy and the agro-industrial complex in Ukraine is highlighted. The theoretical and applied value of the use of the author's method of assessing the level of sustainability in the agro-industrial complex is realized in the identification of "bottlenecks" in com-pliance with the conditions of sustainable development of this sector, which is objectified in the factor of ensuring the envi-ronmental friendliness of production. It is established that the development of the agro-industrial sector within the strategy of predominance of extensive factors, the dominance of economic determinants of functioning was reflected in the neglect of environmental parameters.
Keywords: sustainable development, level of economy sustainability, level of sustainability of agro-industrial com-plex, integrated assessment of sustainability level.
Evaluation of Nephroprotective Effects of Lawsonia inermis Bark Extract: A Biochemical Approach
Authors: Mohammad Firdous Sayeed , Fayed Marwa A. A.
Published: December 2022

Gentamicin is atypical aminoglycoside medication used to treat bacterial infections. Gentamicin-induced nephrotoxicity is classified as a tubulopathy, in which tubular damage and destruction most frequently cause renal insufficiency. Our study aims to evaluate the nephroprotective effects of Lawsonia inermis bark extract against gentamicin-induced nephrotoxicity in rats. Animals were divided into four groups (n = 6). Group I served as a normal control group, group II served as a gentamicin control group, and in Groups III and IV, gentamicin-challenged animals were treated with L. inermis bark extract at doses of 100 mg/kg and 200 mg/kg, respectively. Based on the results, we found that treatment with L. inermis bark extract at doses of 100 mg/kg and 200 mg/kg significantly reduced the elevated creatinine and urea in the blood. Besides, the extract also improved the total protein level in the blood. It is well known that gentamicin intoxication reduces antioxidant defense, so we examined the levels of endogenous antioxidants (superoxide dismutase, catalase, and reduced glutathione) and discovered that the extract at doses of 100 mg/kg and 200 mg/kg significantly improved the activity of these antioxidants. Hence, we can conclude that the nephroprotective potential of L. inermis bark extract may be attributed to its antioxidant activity.
Soil Parameters of Creep Movement Şirinköy-Denizli Example
Authors: İlkimen Elif Meriç
Published: December 2022

This study, it is aimed to determine how soil parameters affect mass movement. The study area was carried out in the Şirinköy District of Merkezefendi District of Denizli. As a basis for the prevention of mass movements; Geophysical methods are of great importance in terms of determining and monitoring the properties of the sliding forces by determining the ground conditions in the region. For this reason, in this study, the characteristics of the mass movement were determined by determining the soil properties of the study area by using the seismic multi-channel surface wave (MASW) method, which is one of the geophysical methods. With the MASW method, it was determined that the seismic velocities of the area were lower than 910 m/s. The boundaries and units of the geological formations of the ground in the region have been determined. Limestone and fill surface slip surfaces in the area were observed in MASW sections. By evaluating all these studies together, the mass movement in the region was determined as slow flow (creep). Blocky limestone detected in the study area (it is the unit that relatively forms the slip surface. For this reason, developments such as groundwater, growth of roots of plants and trees, wetting, drying and freezing of the ground with the effect of precipitation may cause an acceleration of the movement speed should be followed.
Relation of Parental Involvement and Goal Orientation in Adolescents
Authors: - Azra Praveen , - Jyoti Bhatt
Published: December 2022

The present study aims to find out the effect of parental involvement on the goal orientation of adolescents. This study had been conducted on a sample of 150 adolescents (75 males and 75 females) randomly selected from various schools of the Nainital district of Uttarakhand. For the data collection of parental involvement 'Parental Involvement Scale' by Chauhan & Arora (2009) and for the data collection of goal orientation 'Goal orientation Test' by Shreekala (2013) was used. For the analyses of data, ANOVA had been used. The findings of the study revealed that there is no significant difference among the adolescents of three groups i.e high, average and low. Male and female participants differ significantly on goal orientation and the Study also revealed that there is a significant difference among parental involvement and gender.
Bakha’s Identity as an Anglophilic Assimilado in the Context of a Colonized India: A Postcolonial Reading of Mulk Raj Anand's Untouchable
Authors: - Tansim Zannat
Published: December 2022

This study aimed to illustrate how Bakha's Subalternity is intricately woven with the establishment of his identity as an assimilado as well as Anglophilic in the context of a colonized India, and also exhibit how this Anglophilia and assimilation of Bakha have been illustrated by Mulk Raj Anand within his literary production titled Untouchable by conducting a postcolonial investigation of the selected text. It followed the unstructured mode of inquiry that is the Qualitative approach of research. The style used to design this paper is exploratory and descriptive. The findings of the paper revealed the way Bakha gets succumbed into the spiral of the culture and tradition of the British imperialists and starts to identify himself as an Anglophilic assimilado as a result of his failure to realize the oppressive, autocratic, and dominating natures of the British authoritative figures and the effects of colonization in India due to his subaltern status within the society, which is the outcome of the Repressive Ideology practiced by the Indian Hindu community promoting class discriminations and caste-conflicts. The study further revealed how Bakha's Anglophilia and assimilation have found their outlets within the selected text through the employment of numerous significant postcolonial terms and concepts including ‘mimicry’, ‘mimic men’, and the psychopathological concept associated with colonialism that reveals the psychological effects of colonialism, which results in psychological inadequacy that eventually causes Anglophilia and makes a colonized person an assimilado. Lastly, this particular paper is helpful for academicians willing to gather more knowledge about the postcolonial notions like subalternity, Anglophilia, and assimilation and study how they are related to one another.
A Brief Review on Green Tea
Authors: - Nayan Dilip Deore , - Rutuja S. Abhonkar
Published: December 2022

Green Tea, which is produced from the leaves of the Camellia sinensis plant and belongs to the family Theaceae, is one of the most popular beverages worldwide. In This paper, the phytochemistry, Pharmacology, and toxicology of green tea are reviewed systematically and comprehensively. Key findings Green Tea has been demonstrated to be good for human health. Nowadays, multiple pharmacologically active components have been isolated and identified from green tea, including tea polyphenols, alkaloids, amino acids, polysaccharides, and volatile components. Recent studies have demonstrated that green tea shows versatile pharmacological activities, such as antioxidant, anticancer, hypoglycemic, antibacterial, antiviral and neuroprotective. Studies on the toxic effects of green tea extract and its main ingredients have also raised concerns including hepatotoxicity and DNA damage. Additionally, Green tea polyphenols induce autophagy, thereby revitalizing the overall health of the organism consuming it. Green tea was able to activate autophagy in HL-60 Xenographs by increasing the activity of P13 kinase and BECLIN-1. This manuscript describes the reported anti-photoaging, stress resistance, and neuroprotective and autophagy properties of one of the most widely known functional foods-green tea.
Gender, Perception and Punishment in Anupma Chandrasekhar’s Free Outgoing
Authors: - Shahbun Nisha
Published: December 2022

In India, a young girl's sexuality is a matter of public concern due to the fact that globalisation and technological advancements have altered female identities and roles and prepared the way for new perceptions of female identity, particularly in terms of their sexual assertiveness. Free Outgoing calls draw attention to and reveal a multitude of ideological conflicts around gender and sexuality that have been redefined by the internet and smart phones. Based on an actual classroom MMS event involving a young girl, "The MMS Scandal," as it was termed, opened Pandora's box in terms of the young girl's life, sexuality, upbringing, and morality, which became debatable within her family, political organisations, and more so in the media. It only took one click for the entire nation to despise her and be prepared to punish her.
Synthesis, Characterization and Biological Evaluation of 6-(5-Chloro-8-Hydroxynapthalene-2-yl)-4(4-Hydroxyphenyl)-4-5-Dihydroxypyrimidin-2(1h)-One
Authors: - V.M. Sherekar , - N.S. Padole , - K.P. Kakade
Published: December 2022

1-(4- Chloro -1-hydroxynaphthalen-2-yl)-ethanone was prepared by refluxing 4-chloronaphthalen-1-ol with glacial acetic acid in presence of fused ZnCl2. From this synthesized compound we prepared 1-(4- Chloro -1- hydroxynaphthalen-2-yl)-3-(4-hydroxy phenyl)-prop-2-en-1-one from condensing 1-(4- Chloro -1-hydroxynaphthalen-2- yl)-ethenone, The final product 6-(5-chloro-8-hydroxynapthalene-2-yl)-4(4-hydroxyphenyl)-4-5-dihydroxypyrimidin-2(1h)-one, by condensation in presence of urea and concentrated HCl in DMF. The compounds thus synthesized have been characterized by physical and spectral data. This titled synthesized compound was screened for antimicrobial study and are found to possess excellent antimicrobial activities due to presence of chlorine as a substituent on main nucleus.
T1w MRI vs STIR MRI vs Conventional Radiography in Evaluation of Seronegative Spondyloarthropathies
Authors: - Ishan Shabir Wani , - Feroze Shaheen , - Mustaq Ahmad
Published: December 2022

Ankylosing spondylitis and other seronegative arthropathies are conventionally diagnosed using clinical criteria and xrays of SI joints and spine. The introduction of MRI particularly the STIR sequence has revolutionised the diagnosis and assessment of activity of the diseease. But as inferred from this study MRI is not infallible and xrays maybe superior to MRI to identify the structural changes and low dose CT maybe a good alternative to even MRI to establish the Diagnosis.