bluuebunny/crossref_metadata_2025 huggingface dataset:
Pancreatico-jejunostomy versus pancreatico-gasrostomy after pancreatico-duodenectomy in decreasing postoperative pancreatic fistula
Authors: Shaeir Sayed Shaker , ElKordy Mohamed Atef , Sobeih Mohamed Emam , Allam Rasha Mahmoud , Hanafy Ayman
Published: August 2023

Background

Pancreatico-duodenectomy is still the cornerstone in curating pancreatic and periampullary cancers. Many techniques for pancreatic anastomosis were described. Pancreatico-gastrostomy (PG) may be a suitable technique, especially in small pancreatic ducts where the stitching of duct to mucosa may be difficult. Still, the results of pancreatico-gastrostomy compared to pancreatico-jejunostomy (PJ) in terms of morbidity are not well studied; hence, this study was designed to investigate.

Objective

To compare pancreatico-gastrostomy versus pancreatico-jejunostomy post pancreatico-duodenectomy from points of operative techniques and characteristics, and postoperative morbidity and mortality.

Patients and methods

The Cohort study included all cases diagnosed with either pancreatic head or periampullary cancers and underwent pancreatico-duodenectomy at National Cancer Institute (NCI), Cairo University, between January 2021 and February 2023. Cases were enrolled into one of the two groups, group 1: underwent pancreatico-gastrostomy, while group 2 underwent pancreatico-jejunostomy. The two groups were compared by: Demographic characteristics, preoperative investigations results, operative, postoperative data and histopathological results of the specimens resected.

Results

Incidence of the pancreatic leak was not significantly different in both groups (17.6% versus 15.8% for PG and PJ respectively, P=0.833), operative time was shorter in a pancreatico-gastrostomy group (310, 355 min, P=0.001), Delayed gastric emptying (DGE) was less occurred in cases of pancreatico-gastrostomy (5.9%, 31.6%, P=0.006). Postoperative mortality was not different in both groups (8.8%, 2.6% for PG and PJ respectively, P=0.338).

Conclusion

Regarding the incidence of postoperative pancreatic fistula, both reconstruction methods produce comparable postoperative results. Pancreatico-gastrostomy is a good alternative technique to the standard pancreatico-jejunostomy.
Epidermal Growth Factor Receptor Mutated Lung Cancer Presenting as Synchronous with a Recurrent Nonhuman Papillomavirus-Related Head-and-Neck Squamous Cell Carcinoma
Authors: Fonseca Daphne , Arya Sahithi Shilpa , Kunteepuram Vaishnavi , Raju K. V. V. N. , Rajappa Senthil
Published: August 2023

A patient with nonhuman papillomavirus (HPV)-related head-and-neck cancers is at an increased risk of developing second primary malignancies. We present a case of non-HPV-related squamous cell carcinoma (SCC) of the left lower alveolus who presented with locoregional recurrence in the left upper lip 3 years after initial treatment with chemoradiotherapy along with a synchronous Epidermal growth factor receptor(EGFR)mutated lung adenocarcinoma. Comprehensive genomic profiling will guide diagnosis and therapy in these cases. Registry of synchronous tumors would help design protocols for better management.
Effect of Moderate Intensity Aerobic Exercise on Fertility Hormones in Male Obese Individual in Nnewi, Nigeria
Authors: Onuora Ifeoma Joy , Meludu Samuel Chukwuemeka , Dioka Chudi Emmanuel , Obi-Ezeani Chikaodili Nwando
Published: August 2023

Context:

Obesity is a major global public health issue which could result from sedentary lifestyle and poor dieting, and consequently hormonal imbalance.

Aim:

To evaluate fertility hormones in male obese subjects, and the subsequent effect of moderate intensity aerobic exercise on these parameters after 12 weeks of intervention.

Subjects and Methods:

90 obese (48 class I and 42 class II) and 50 normal weight (control) subjects were recruited. Subsequently, 18 male obese subjects were randomly selected and subjected to a 12-week aerobic training program using a total cross bar machine, three sessions weekly, which consisted of a 10–15 min warm-up and 35–50 min total cross bar machine exercise. Blood samples were collected at baseline, 6 weeks and after 12 weeks of intervention for luteinizing hormone, follicular stimulating hormone (FSH), prolactin, testosterone, and estradiol using enzyme-linked immunoassay.

Statistical Analysis:

Statistics was done using SPSS version 23.

Results:

The mean level of testosterone and FSH was significantly lower while estradiol was significantly higher in class I and II when compared with the control (P < 0.05). On subjecting them to 12 weeks exercise, there were significant increases in FSH and testosterone and decrease in estradiol when compared with the baseline values (P < 0.05).

Conclusion:

Weight loss through moderate intensity exercise may improve the reproductive hormone profile of male obese individuals, thereby reducing rate of infertility.
A New Approach for the Management of Knee Hyperextension in Pediatric Cases
Authors: Chechani Gouri RajendraKumar , Patel Sahil
Published: August 2023

Background:

Knee hyperextension can be a serious and disabling injury in both the athletic and general patient population. The flexible type of knee hyperextension can be controlled by either static or dynamic knee orthosis. An important aspect of patient care in knee hyperextension is the application of proper knee orthosis. Knee orthosis is a nonoperative method for the management of knee hyperextension. It is a challenging task in this new engineering field of orthotic science for the orthotist to design suitable orthosis for knee hyperextension. The modern method of orthotic technology needs changes to benefit patients with knee hyperextension to fulfill the functional need for the user. A knee orthosis should, hypothetically, allow full range of motion, except it limits where there will be orthotic constraints. This knee orthosis is a modified polypropylene knee hyperextension orthosis for nonoperative management of knee hyperextension.

Aims and Objective of the Study:

The purpose of the design is to provide a nonoperative solution to control knee hyperextension in pediatrics for the prevention of knee structures by changing the line of force.

Materials and Methods:

It is a custom-made orthosis made of polymer sheet with a hinged knee joint with thigh shell and leg shell placed in the contralateral side and provides a rigid support for the knee without hindering knee flexion with full restriction of knee hyperextension. There will be no suprapatellar protrusion like the one conventional plastic supracondylar knee orthosis.

Results:

Based on observational gait analysis, molded polypropylene knee hyperextension orthosis provides a stable gait pattern with a minute or no gait deviation from the normal gait parameters (gait parameters varies between different subjects).

Conclusions:

A technique has been proposed for the management of genu recurvatum. A theoretical and practical justification for the method has been presented, and a thorough analysis is required. The use of modified knee orthosis appears to give protection against the anterior tibial translation, thus preventing hyperextension and gives a better gait with the help of initial flexion angle.
Adverse Event Following Immunization and Relation with Blood Group Following COVID19 Vaccination among Indian Community
Authors: Pandit Niraj , Patel Nilesh
Published: August 2023

Introduction:

In middle of the 3rd wave, COVID19 is now gradually making agent host environment balance at the world level. COVID19 vaccine is also available for the prevention of diseases. The two vaccines which are available in India till July 2021, they are COVISHIELD and Covaxin. There are various news heard about the relation of the ABO blood group and COVID19 disease. However, no study has tried to the relation of various blood groups and adverse events following immunization (AEFI).

Methods:

This was a community-based cross-sectional study. It was conducted online mode with the use of Google Forms. Study participants were Indian citizens and who took either Covishield or Covaxin as COVID19 vaccination. The pretested form was used, which consisted of various information regarding blood group of individual, vaccine, type of vaccine, doses of vaccine, side effects postvaccination, what is/are side effects and other information like do you have disease COVID19.

Results:

A total of 893 participated in the study, but out of them, 731 participants took vaccine either one or two doses. Most of the participants, 597 (87%), were from urban areas. The postCOVID19 vaccine AEFI prevalence was 69.7%. The association between ABO and Rh blood group and AEFI was not statistically significant. However, Covaxin has lesser side effects compared to COVISHIELD. Even a small group of COVID19 disease also had no association with ABO or Rh blood group.

Conclusion:

The side effects following the COVID19 vaccine are quite common. Majority were mild AEFI. There is no statistical association with blood group and postCOVID19 AEFI.
Zinc and Anthropometry in Sickle Cell Disease
Authors: Alaka Anuoluwa Abisola , Alaka Olubunmi Olayemi , Iyanda Ayobola Abolape
Published: August 2023

Introduction:

Homozygous rather than heterozygous sickle cell disease (SCD) is considered the more severe form of the disorder. While some markers have been used successfully to distinguish between the two with respect to disease severity, the role of other markers remains either inconclusive (e.g., nitric oxide) or ambiguous (e.g., anthropometry). The objective of the study was to provide information about possible variations in anthropometry and zinc (Zn) levels among SS and SC patients in Osun State, Nigeria.

Materials and Methods:

Adult participants enrolled consisted of 34 SS hemoglobinopathy (also known as HbSS); 32 SC hemoglobinopathy (commonly referred to as HbSC) patients and 32 with HbAA as control. Serum Zn estimation was done by atomic absorption spectrophotometry. Anthropometry (body weight, standing height, body mass index [BMI], head and mid-upper-arm circumferences [MUACs]) was determined using standard procedures. Data were analyzed with analysis of variance and Pearson correlation coefficient. P < 0.05 was considered statistically significant.

Results:

All anthropometric parameters were significantly lower for SCD patients compared with control, but only body weight was significantly different when HbSS and HbSC were compared. Serum Zn status of control was higher than those of SCD patients, with HbSS values being more significantly lower than those of HBSC. Among the HbSS as well as HbSC patients, there was a positive correlation between BMI and Zn as well as between HC and MUAC.

Conclusion:

Results of the study indicate that while the Zn status of HbSS and HbSC were significantly different, most of the anthropometric parameters were not significantly different.
Introduction of psychological skills laboratory in medical education
Authors: Chen YY , Ting CH
Published: August 2023

Depression and anxiety are common psychological issues among university students, yet many of them hesitate to seek professional help due to stigma. Unfortunately, university curricula often lack self-help strategies to manage these challenges and provide timely support to those in need. To address this gap, we introduced the Psychological Skills Lab (PSL) component in the undergraduate medical curriculum, which emphasizes experiential learning to promote self-determination and autonomy in health promotion. The lab allows active interaction among students, lecturers, and peers through activities like presentations, peer reviews, in session practice, gratitude journals, group discussions, and role plays. PSL helps students develop skills, empathy, mindfulness, and self compassion through regular interactions. This innovative teaching approach raises mental health awareness and empowers students to assist others when required. Thus, by incorporating self-help measures into the curriculum, students are better equipped to manage their emotional well-being while supporting those around them.
Factors Influencing Quality of Life after Lower Extremity Amputation
Authors: Thomas Dantis John , Rajendran C. V.
Published: August 2023

Background:

Despite the fact that patients with critical limb ischaemia, diabetic foot, advanced malignancies and major trauma to extremities undergo lower limb amputation, the personal satisfaction or quality of life (QoL) of such patients remains inadequately portrayed. This study tried to portray which spaces' amputees consider significant in deciding their well-being related QoL.

Objective:

To study the factors influencing QoL of patients who have undergone lower extremity amputation attending the department of general surgery of a tertiary hospital and to compare the QoL of amputee population with that of general population.

Methodology:

It was a cross-sectional study. The study population included patients who underwent lower extremity amputation in the department. 110 subjects, aged above 18 years, who have undergone lower extremity amputation and who consented to take part in the study were included.

Results:

The QoL as calculated from the Physical Component Summary and Mental Component Summary scores, using short-form-36 questionnaire showed that the physical health and the mental health (MH) both were significantly low in the amputee population. It was seen that gender with female sex having a better physical health quality compared to the male sex. Gender, use of prosthetic devise, stump infections and employment status contributed to MH quality. The QoL of an individual was severely altered following amputation. Both physical and MH domains were significantly reduced in an amputee compared to the general population. Gender influenced both the mental and physical QoL, with females performing better. Use of prosthesis was seen to be significant in MH. This underscores the need for proper rehabilitation programmes.

Conclusion:

The factors recognised should be seriously addressed in order to improve the QoL of lower limb amputees.
Factors Associated with Development of Post-Operative Pancreatic Fistula
Authors: George Amal , Sajan P. , Kuruvilla Rojan , Viswanath U. V. Akshay , Augustine Jinto Thomas , Rajan Abishek , Nambiar Rajesh , Sahadevan Sajeesh , Noushif M.
Published: August 2023

Introduction:

Post-operative pancreatic fistula (POPF) is one of the major complications of pancreaticoduodenectomy (PD), which is the procedure of choice for many peripancreatic diseases. POPF may lead to or be combined with post-pancreatectomy haemorrhage and delayed gastric emptying or abscesses and sepsis, possibly leading to subsequent shock, multiorgan failure and mortality. The study was conducted with the objective to identify the factors associated with the development of POPF following PD.

Methodology:

This was a record-based cross-sectional study done in Kerala which recorded the details of 125 patients who underwent surgery between January 2018 and January 2020. Inclusion criteria were patients admitted with pathology in and around the head of the pancreas and requiring PD. Patient characteristics, disease-related details, pre-operative morbidities, details of surgery, and post-operative details were accessed from the patient record.

Results:

The mean standard deviation age of the participants was 60 (11.2) years. There was a higher proportion of males compared to females. The underlying lesion was malignant for the majority. Nearly 90% of the participants underwent classical PD. Nearly half of the patients developed POPF of which one-third were clinically relevant. Lack of history of chronic pancreatitis and post-operative drain fluid amylase was found to be significantly associated with POPF occurrence.

Conclusion:

Lack of history of chronic pancreatitis, amount of drainage fluid and amylase level was found to be significantly associated with the presence of post-operative fistula.
Primary Jejunal Melanoma Presenting as Gastrointestinal Bleeding
Authors: Babu Agil , Haridas T. V. , Abdul Siyad A. K. , Daniel Bevin Roys , Radhakrishnan K. N.
Published: August 2023

Intestinal melanomas are very rare causes of upper gastrointestinal bleeding and abdominal lump. The occurrence of both primary and secondary in the intestine is an uncommon presentation. Jejunal melanoma is extremely rare, and only <20 cases have been reported in the literature so far. We are presenting a 52-year-old male patient who presented with fatigue, melaena and an abdominal lump of 1-month duration. He was operated on for biopsy as none of the investigations helped in reaching a definitive diagnosis. Peroperative findings were indicative of jejunal melanoma with infiltration to the right colon. Right hemicolectomy with jejunal resection was done. Histopathological examination revealed malignant melanoma with primary from jejunum. This case is discussed because of the rarity of the disease, and better management can be planned if preoperatively diagnosed.
A Study to Determine the Incidence of Coexisting Carcinoma In situ in Mastectomy Specimens with Invasive Breast Carcinoma
Authors: Prakash Bineesh , Mohanan P K
Published: August 2023

Background:

In situ breast carcinoma is a pre-invasive cancer that has not breached the epithelial basement membrane. This was previously a rare but is becoming increasingly common. It may be ductal carcinoma in situ (DCIS) or lobular carcinoma in situ (LCIS). DCIS is a precursor of invasive carcinoma, whereas LCIS is not a precursor but only a predictor of invasive carcinoma. In those with LCIS, 50% of the carcinomas occur in the contralateral breast.

Aim:

This paper aims to study the incidence of DCIS and LCIS in mastectomy specimens of invasive carcinoma breast.

Materials and Methods:

This is a subjective study of 226 patients in a tertiary care hospital over a period of 18 months. Patients with invasive breast carcinoma undergoing mastectomy were included. Patients with invasive breast carcinoma and those who have undergone any breast surgeries in the past were excluded. The histopathology reports were analysed for finding out DCIS and LCIS coexisting with invasive carcinoma of the breast.

Results:

The patients had a mean age of 56–11.025 years. 59.7% were in the 41–60-year age group. DCIS coexisted with invasive carcinoma in 28.3% (64). LCIS was absent in all cases of invasive carcinoma. Amongst those with DCIS, high-grade DCIS was found in 65.6% (42) and low-grade DCIS in 34.4% (22). Amongst the DCIS group, comedo type was present in 46.9% (30), followed by cribriform type 31.2% (20), solid type 18.8% (12) and papillary type 3.1% (2).

Conclusion:

DCIS was found to coexist with invasive carcinoma in 28.3% of cases, whereas LCIS was absent in all cases of invasive carcinoma.
Gestational diabetes mellitus and COVID-19: The epidemic during the pandemic
Authors: Mendez Yamely , Alpuing Radilla Linda A , Delgadillo Chabolla Luis Eduardo , Castillo Cruz Alejandra , Luna Johanan , Surani Salim
Published: August 2023

The incidence of type 2 diabetes mellitus is growing in epidemic proportions and has become one of the most critical public health concerns. Cardiovascular complications associated with diabetes are the leading cause of morbidity and mortality. The cardiovascular diseases that accompany diabetes include angina, myocardial infarction, stroke, peripheral artery disease, and congestive heart failure. Among the various risk factors generated secondary to hyperglycemic situations, advanced glycation end products (AGEs) are one of the important targets for future diagnosis and prevention of diabetes. In the last decade, AGEs have drawn a lot of attention due to their involvement in diabetic patho-physiology. AGEs can be derived exogenously and endogenously through various pathways. These are a nonhomogeneous, chemically diverse group of compounds formed nonenzymatically by condensation between carbonyl groups of reducing sugars and free amino groups of protein, lipids, and nucleic acid. AGEs mediate their pathological effects at the cellular and extracellular levels by multiple pathways. At the cellular level, they activate signaling cascades via the receptor for AGEs and initiate a complex series of intracellular signaling resulting in reactive oxygen species generation, inflammation, cellular proliferation, and fibrosis that may possibly exacerbate the damaging effects on cardiac functions in diabetics. AGEs also cause covalent modifications and cross-linking of serum and extracellular matrix proteins; altering their structure, stability, and functions. Early diagnosis of diabetes may prevent its progression to complications and decrease its associated comorbidities. In the present review, we recapitulate the role of AGEs as a crucial mediator of hyperglycemia-mediated detrimental effects in diabetes-associated complications. Furthermore, this review presents an overview of future perspectives for new therapeutic interventions to ameliorate cardiovascular complications in diabetes.
Diabetes mellitus as a consequence of acute severe pancreatitis: Unraveling the mystery
Authors: Manrai Manish , Singh Anupam K , Birda Chhagan Lal , Shah Jimil , Dutta Aditya , Bhadada Sanjay Kumar , Kochhar Rakesh
Published: August 2023

The incidence of type 2 diabetes mellitus is growing in epidemic proportions and has become one of the most critical public health concerns. Cardiovascular complications associated with diabetes are the leading cause of morbidity and mortality. The cardiovascular diseases that accompany diabetes include angina, myocardial infarction, stroke, peripheral artery disease, and congestive heart failure. Among the various risk factors generated secondary to hyperglycemic situations, advanced glycation end products (AGEs) are one of the important targets for future diagnosis and prevention of diabetes. In the last decade, AGEs have drawn a lot of attention due to their involvement in diabetic patho-physiology. AGEs can be derived exogenously and endogenously through various pathways. These are a nonhomogeneous, chemically diverse group of compounds formed nonenzymatically by condensation between carbonyl groups of reducing sugars and free amino groups of protein, lipids, and nucleic acid. AGEs mediate their pathological effects at the cellular and extracellular levels by multiple pathways. At the cellular level, they activate signaling cascades via the receptor for AGEs and initiate a complex series of intracellular signaling resulting in reactive oxygen species generation, inflammation, cellular proliferation, and fibrosis that may possibly exacerbate the damaging effects on cardiac functions in diabetics. AGEs also cause covalent modifications and cross-linking of serum and extracellular matrix proteins; altering their structure, stability, and functions. Early diagnosis of diabetes may prevent its progression to complications and decrease its associated comorbidities. In the present review, we recapitulate the role of AGEs as a crucial mediator of hyperglycemia-mediated detrimental effects in diabetes-associated complications. Furthermore, this review presents an overview of future perspectives for new therapeutic interventions to ameliorate cardiovascular complications in diabetes.
Potential role of microRNA-503 in Icariin-mediated prevention of high glucose-induced endoplasmic reticulum stress
Authors: Su Bao-Lin , Wang Liang-Liang , Zhang Liang-You , Zhang Shu , Li Qiang , Chen Gang-Yi
Published: August 2023

The incidence of type 2 diabetes mellitus is growing in epidemic proportions and has become one of the most critical public health concerns. Cardiovascular complications associated with diabetes are the leading cause of morbidity and mortality. The cardiovascular diseases that accompany diabetes include angina, myocardial infarction, stroke, peripheral artery disease, and congestive heart failure. Among the various risk factors generated secondary to hyperglycemic situations, advanced glycation end products (AGEs) are one of the important targets for future diagnosis and prevention of diabetes. In the last decade, AGEs have drawn a lot of attention due to their involvement in diabetic patho-physiology. AGEs can be derived exogenously and endogenously through various pathways. These are a nonhomogeneous, chemically diverse group of compounds formed nonenzymatically by condensation between carbonyl groups of reducing sugars and free amino groups of protein, lipids, and nucleic acid. AGEs mediate their pathological effects at the cellular and extracellular levels by multiple pathways. At the cellular level, they activate signaling cascades via the receptor for AGEs and initiate a complex series of intracellular signaling resulting in reactive oxygen species generation, inflammation, cellular proliferation, and fibrosis that may possibly exacerbate the damaging effects on cardiac functions in diabetics. AGEs also cause covalent modifications and cross-linking of serum and extracellular matrix proteins; altering their structure, stability, and functions. Early diagnosis of diabetes may prevent its progression to complications and decrease its associated comorbidities. In the present review, we recapitulate the role of AGEs as a crucial mediator of hyperglycemia-mediated detrimental effects in diabetes-associated complications. Furthermore, this review presents an overview of future perspectives for new therapeutic interventions to ameliorate cardiovascular complications in diabetes.
Position of the Local Development Fee in the System of Local Taxes and Fees in the Slovak Republic
Authors: Vartašová Anna , Červená Karolína
Published: August 2023

In the article, the authors focused on the application of the most recently introduced optional local fee in the Slovak Republic, namely the local development fee. Since 2017, the income from the fee has been a source of funding for the municipalities that have introduced it in their territory by a generally binding ordinance. The article aims to identify the position and budgetary significance of this fee and to evaluate its development in the period since its introduction, at the national level in Slovakia in comparison with the trend in the capital of Slovakia - Bratislava. The authors conclude that the fee is being imposed by a permanently rising number of municipalities and increasing incomes from the fee are observed. The importance of the fee as a source of funding was identified at a case-to-case level, even though its significance at the overall level of Slovakia is yet low.
The Importance of the Application of Controlling in the Management of Public Enterprises whose Founders are Local Self-government Units: The Example of Republic of Serbia
Authors: Vitomir Jelena , Tomas-Miskin Sonja , Popović Slobodan
Published: August 2023

The importance of the application of controlling in public enterprises is highlighted in the study. The aim of the research was aimed at establishing evidence that improvement of management can be achieved through the application of controlling 141 public companies were analyzed in terms of the use of controlling and internal control, that is, about 20% of the mentioned companies whose founders are local self-government units. We found that there are significant differences in terms of established control and it is increasingly in favor of the application of controlling in relation to internal control based on the analyzed five factors: planning, decision-making, business analysis, presentation and reporting. The main conclusion would be that the operations of public companies in the coming period will require an increasing application of controlling in the management system. This was determined by applying the so-called T-test, and the total score, and it refers to all analyzed factors (p=.000) in relation to established controlling and internal control in public companies.
Rönesans dönemi resim sanatında vaftiz sahnelerinin bir grup sanatçı üzerinden değerlendirilmesi
Authors: Toptaş Rahşan
Published: August 2023

Rönesans dönemi resim sanatında çoğunlukla mitolojik ve dini konuların işlendiğini görülmektedir. Dini konularda genellikle İsa’nın hayatından sahneler canlandırılmıştır. Bu sahneler arasında vaftiz, dinsel bir ritüel olması sebebi ile özellikle kiliselerde yer almıştır. Çalışma ile vaftiz konusu tarih aralığı bakımından Rönesans dönemi ile sınırlandırılmıştır. Bu dönemin belli başlı sanatçılarının eserleri taranarak konunun nasıl işlendiği, geçmiş dönemlerdeki işleniş şekli ve sonrasında geçirdiği değişim üzerinde durulmuştur. Bu bağlamda konu Gotik, Maniyerist ve Barok dönem örnekleri ile karşılaştırılarak değerlendirilmiştir. Vaftiz sahnelerinde dönem içinde genel olarak konu dışına çıkılmadığı görülmüştür. Rönesans dönemi resim sanatında perspektif, renk, figür ve çizgi değişim geçirmiştir. Gerçekleşen değişim eserlere yansımıştır.
A MATHEMATICAL MODEL FOR THE LOCATION OF CHARGING STATION FOR ELECTRIC BUSES
Authors: DİNÇ YALÇIN Gülçin , DOĞAN Ece , KAYA Ahmed Yasin , OĞUZ Enes Can
Published: August 2023

In order to create sustainable solutions, the use of electric vehicles instead of traditional vehicles, which is called fossil fuel vehicles, is significant. It is essential to determine the locations of the charging stations to be established so that electric vehicles can be preferred in intercity buses, which are frequently used in the transportation network. For the selection of locations of the charging stations, there are limitations such as waiting times at the charging stations, having sufficient charge for the next stop, and especially the budget. In addition, determining the candidate charging stations among the existing bus stops would increase customer satisfaction as it would prevent extra breaks. However, it may not be possible to use electric buses on every bus route due to both driving range and budget constraints. For this reason, in this paper, a multi-objective mathematical model that minimizes the number of charging stations and maximizes the number of electric buses is proposed and the weighted sum method is used to solve this model. In addition, the proposed mathematical model was solved using the General Algebraic Modeling System (GAMS) with the data of a bus company in Türkiye.
Evaluation of a pharmacy emergency response conference workshop
Authors: McCourt Elizabeth , Watson Kaitlyn
Published: August 2023

Background: The importance of pharmacists' involvement in disasters is becoming increasingly recognised in the literature. The aim of this project was to determine the effectiveness of a disaster workshop in improving pharmacy staff’s perceived capabilities to prevent, prepare for, respond to, and recover from disasters.   
Methods: A disaster workshop was provided at a pharmacy conference. The workshop incorporated an evolving emergency scenario in which participants worked through activities pertaining to the prevention, preparedness, response, and recovery cycles. The attendees were invited to complete a previously validated pre-post survey assessing their perceptions of their skills and capabilities in the components of disaster management.
Results: The pre-post survey was completed by 31 attendees.  After the workshop, participants' perceptions of their ability to prevent, respond to, and recover from a disaster significantly improved (p=0.004, 0.013, and 0.013, respectively).    
Conclusion: This study demonstrated that a conference disaster workshop can improve the understanding and perceived disaster capabilities of health-system pharmacy personnel.
Impacts of a university philosophy outreach program at Kailua High School
Authors: Makaiau Amber , Miller Chad , J Chung-Do Jane , Ichinose Amber , Zhang Jianhui
Published: August 2023

The University of Hawai’i at Mānoa’s Uehiro Academy for Philosophy and Ethics in Education (UHM Uehiro Academy) prepares, supports and sustains philosophy for children Hawai‘i (p4cHI) educators, researchers, and students in Hawai‘i and beyond. This paper documents the impact of the Uehiro Academy’s philosophy outreach program at Kailua High School (KHS), a public secondary school on the Hawaiian Island of O’ahu. It describes the twenty year partnership between the University and KHS, which built a foundation for p4cHI to become integrated across the curriculum and within the school culture. To better understand the overall impact of the UHM Uehiro Academy philosophy outreach program on KHS, researchers asked, ‘How has the UHM Uehiro Academy philosophy outreach program impacted the school culture at KHS?’ Qualitative methods were applied to design and conduct a research study, which included interviewing 68 members of the KHS community. Data analysis revealed four main themes: (1) a schoolwide learner-centred pedagogy, (2) a place for learning more than just academics, (3) a community of diverse and connected individuals, (4) a commitment to professional growth for the purpose of a better world. The paper ends with conclusions, implications of the findings, and the researchers reflecting on the findings, including the benefits and challenges of university philosophy outreach programs in the secondary school setting.
The Business Diplomacy of Mayora Indah Ltd. on The Kopiko Brand Through Export to the Philippines and Promotions on Korean Dramas
Authors: Salam Syahrul , Juned Mansur , Utami Rahmadini Agung Ayu
Published: August 2023

Diplomacy in business is needed to make market expansion activities more effective. This step by MNCs is then referred to as business diplomacy and also benefits the state because it can simultaneously become a means of diplomacy and achieve state interests. Mayora Indah Ltd. is a giant MNC from Indonesia that can dominate the global market. The success of Mayora Indah Ltd. in filling the global market can be seen in the popularity of Kopiko as their flagship product. This article aims to determine the strategies of business diplomacy taken by Mayora Indah Ltd to achieve the company's interests successfully.  This article will then review the concepts related to business diplomacy proposed by Alammar & Pauleen (2016) as a foundation for analyzing the case study. This research finds that in the core knowledge competencies, Mayora Indah Ltd. applies internal knowledge through exposure to Kdrama producers related to Kopiko, with the aim that they can understand the product that will later be aired. Meanwhile, on multi-perspective consideration, Mayora Indah Ltd. invests in manufacturing in the Philippines and buys coconut commodities for environmental scanning.
Virtual Reality and Language Learning in Hospitality: An Investigation of Students' Perceptions
Authors:   English Language Teaching Department, Universitas Lampung, Pramasta Rendi Gusti , Ari Wibowo Yusep Windhu ,   English Language Teaching Department, Universitas Lampung
Published: August 2023

This research investigates the perceptions of students within the hospitality management program at Politeknik Negeri Lampung (Polinela) regarding the utilization of Virtual Reality (VR)-based learning in English for Hospitality, a specialized branch of English for Specific Purposes (ESP). With a qualitative approach, the study aims to uncover students’ perspectives on both the challenges encountered and the aspects appreciated in the context of VR-based language learning. The participants, comprising 23 individuals, responded to open-ended questions that aimed to delve into their experiences. The findings shed light on the feasibility and effectiveness of VR-based learning, with the majority of participants reporting minimal difficulties. Appreciation for the immersive learning experience, novelty, realism, and engagement factors were evident in their responses. This research contributes to the understanding of incorporating innovative technologies like VR in ESP contexts, highlighting the need to address technical challenges and optimize language support for a diverse learner population. The outcomes offer insights into the potential of VR-based learning to enhance language acquisition within specific vocational domains.
Heel Reconstruction with Medial Plantar Flap after Excisional Biopsy for Melanoma: Case Report
Authors:   General Surgery Service of the Regional General Hospital 6 of the Mexican Institute of Social Security, Ciudad Madero, Tamaulipas, Abraham Alejandro Castillo Hernández , Alejandro Méndez Bizarrón ,   General Surgery Service of the Regional General Hospital 6 of the Mexican Institute of Social Security, Ciudad Madero, Tamaulipas, Brenda Odilia Salazar Sáenz ,   General Surgery Service of the Regional General Hospital 6 of the Mexican Institute of Social Security, Ciudad Madero, Tamaulipas, Rodríguez Nicolas Sánchez ,   Surgical Oncology Service of the Regional General Hospital 6 Ciudad Madero, Tamaulipas
Published: August 2023

The coverage of soft tissue deficit of the heel, continues to represent a great surgical challenge due to the unique features in this area, developed to withstand large axial and shear loads. The coverage of the heel wounds is considered a priority through an adequate and lasting surgical option that will be the result of a decrease in the morbidity and mortality of the patient.
The Impact of Marketing through Social Media on Brand Attitudes: A Study of Cosmetics Products in Female Generation Z
Authors:   Universitas Negeri Makassar, Indonesia, Ashdaq Muhammad , Alam Syamsu ,   Universitas Negeri Makassar, Indonesia, Aris Valentino ,   Universitas Negeri Makassar, Indonesia, Mandasari Nur Fitriayu ,   Universitas Sulawesi Barat, Indonesia
Published: August 2023

Marketing through social media has become a marketing strategy widely used by the cosmetics industry, especially with the number of consumers that continues to grow as generations increase. Female generation z is a potential market in this industry where they are new entrant consumers and have a relatively large number compared to other generations. This study aimed to investigate the effect of implementing marketing strategies through social media on the attitude of gen z towards cosmetic products in Makassar City, Indonesia. The study was conducted by distributing questionnaires to 288 sample respondents. The primary data was then processed by linear regression using SPSS 23 software. The results showed that marketing through social media has a significant influence on positive attitudes toward cosmetic products. The results of this study have implications that cosmetic companies with a female gen z target market in Makassar City should pay attention to the right social media marketing strategy to get a positive attitude from their consumers.
The Quality of Leader-Member Exchange, Engagement, and Performance: a Systematic Literature Review
Authors:   STIE Malangkuçeçwara Malang, Indonesia, Bagyo Yupono , Dyah Ratnasari Siwi ,   STIE Malangkuçeçwara Malang, Indonesia
Published: August 2023

The past is history, the present is accurate, and the future is uncertain. The world is also getting along with many lives and organizations. Along and within the time, the organizations are apparent with leader-member exchange (LMX) that may be unavoidable, realized in the form of any relationships in the social context. The atmosphere brings forth engagement and performance within groups or communities. The essential variables driving and encouraging LMX to become an interesting research focus among scholars. This work aims to investigate the outstanding characteristics or variables of the quality of LMX following engaged employees and high performance. This study employs a systematic literature review. It explores and identifies the characteristics or variables encouraging LMX, engagement, and performance in the organizations. The conclusion says that it reveals various characteristics or variables of the concepts. However, quite a few of them accommodate the cultural context of a particular life of society, which considerably hinders the sound of the atmosphere.
Forward-Looking Information and its Determinants: an Empirical Evidence from Listed Pharmaceutical Firms of Bangladesh
Authors:   First Author. Professor, Dept. of Accounting & Information Systems, University of Dhaka, Bangladesh., HAQUE Tanzina , AFROZE Sadia ,   Professor, Dept. of Accounting & Information Systems, University of Dhaka, Bangladesh., RAHMAN Md. Musfiqur ,   Professor, Dept. of Accounting & Information Systems, University of Dhaka, Bangladesh.
Published: August 2023

The purpose of this paper is to examine the factors that affect how forward-looking information is disclosed by Bangladeshi 's listed pharmaceutical firms. In this study, a total sample of 115 firms from 23 pharmaceutical firms listed on the Dhaka Stock Exchange (DSE) is considered from the period of 2016 to 2020. Board size, board independence, gender diversity, firm size, leverage, liquidity, and profitability are used as the determinants of forward-looking information. According to the descriptive statistics, the average level of extent of forward-looking information is only 59.33%, which is inadequate for the pharmaceutical industry to survive in the long term. The multiple regression results show that the level of forward-looking information disclosure is positively and significantly associated with board size, firm size, and firm profitability. But the regression results documented that gender diversity, leverage and liquidity and board independence have no significant association with forward-looking information. The findings of this study suggest that companies should focus more on forward-looking information to survive in the market and pursue a competitive advantage. Moreover, the findings of this study also suggest that further research can be conducted using qualitative research in a different sector as well as a cross-country comparison.
The Role of Supply Chain Capabilities in Increasing the Competitive Advantage of Photo Catalyst Ceramic MSMEs in Bali
Authors:   Faculty of Economics and Business, Warmadewa University, Setini Made , Sutapa I Nyoman ,   Faculty of Economics and Business, Warmadewa University, Sitiari Ni Wayan ,   Faculty of Economics and Business, Warmadewa University
Published: August 2023

The long-term goal of this research is to develop knowledge in the field of Strategic Management, especially about Collaborative Value Innovation, Supply chain strategy, strategy of competitive advantage in SMEs. This research was conducted at SMES Photo catalyst Ceramics in Bali, with research objects on collaboration value innovation, supply chain capabilities, competitive advantage. The research population is all ceramic SMEs in Bali. This research was conducted at SMES Photo catalyst Ceramics in Bali, with research objects on collaboration value innovation, supply chain capabilities, competitive advantage. The research population is all ceramic SMEs in Bali. The results of this study indicate that Collaboration of the value of innovation has no significant negative effect on competitive advantage. This indicates that there is no relationship between photo catalyst ceramic SMEs to produce an innovation, so this also provides a negative value in creating competitive advantage between business actors. Collaboration of innovation values provides positive value to supply chain capabilities, collaboration provides great opportunities in sharing information related to resources to support the development of photo catalyst ceramics. The ability of the supply chain to provide significant positive results for competitive advantage, with the capabilities of good information actors from raw materials to ceramic products will certainly provide great opportunities in achieving competitive advantage; this also shows that the mediation of supply chain capabilities becomes full mediation in relationships, collaboration value innovation and competitive advantage.
Consideraciones axiológicas en la formación académica universitaria venezolana
Authors: Rodríguez Lissirt Miguel E
Published: August 2023

La universidad, institución de educación superior, fundamentada en la trilogía academia-investigación y extensión para la producción de conocimientos que conduzcan a la transformación social, mediante el proceso enseñanza aprendizaje aplicados en la sociedad, una vez egresados como profesionales. La universidad venezolana está concebida como una comunidad de intereses espirituales que reúne a profesores y estudiantes en la tarea de buscar la verdad y afianzar los valores trascendentales del hombre. El objetivo de este ensayo es fomentar los valores para ello, es indispensable la axiología que se orienta hacia   la construcción trascendental de los principios y valores del ser humano, que inicia con el “yo” como individuo y se materializa en “nosotros” es decir, lo colectivo o sociedad. El estudio responde a la tipología de investigación cualitativa, y dentro del contexto, se ubica el paradigma interpretativo o constructivista, para la interpretación de la interacción social en la que se propone que se debe estudiar las interpretaciones y significados y ontológicamente, el investigador se relaciona con los sujetos, es decir estudiantes y profesionales de manera intersubjetiva, empleándose además como método, la  fenomenología para dar sentido interpretativo de la conducta de los profesionales en su vivencia personal como colectiva, a través de la descripción y la interpretación  de esas conductas; ya que este método busca descubrir el significado y sentido de las experiencias vividas de las personas. Se concluye que, la axiología como disciplina filosófica, juega un rol de relevancia en la formación académica universitaria, como elemento trascendental del individuo y de la sociedad.
Análise quantitativa de intercorrências em protocolos de toxina botulínica tipo A: uma revisão bibliográfica
Authors: Uhlick Felipe , Leite Cleber
Published: August 2023

O envelhecimento é um processo natural causado por fatores intrínsecos e extrínsecos, sendo a flacidez da pele uma das características mais marcantes. Essa flacidez tissular, juntamente com outros fatores, como o enrijecimento da musculatura ocasiona rugas e marcas de expressão, o que também traz consigo a insatisfação com a aparência, problemas relacionados a autoestima e demais fatores emocionais. Nesse quesito, a estética funciona como um aliado no desenvolvimento do bem-estar das pessoas, e dentro de protocolos estéticos podemos ressaltar a toxina botulínica tipo A, como fundamental nesse processo de rejuvenescimento facial. A toxina botulínica tipo A, uma proteína produzida em laboratório por meio da bactéria Clostridium botulinum, é uma substância biocompatível com o organismo humano e uma de suas principais funções estéticas é amenizar efeitos causados pelo tempo, de uma forma mais segura que outros métodos mais invasivos, como cirurgias. Mesmo sendo relativamente seguro, ao realizar a aplicação da toxina botulínica é necessário levar em consideração algumas contraindicações como processo inflamatório no local da aplicação, uso de alguns medicamentos, gravidez e lactação. Além disso, também pode haver intercorrências ao realizar esse tipo de procedimento, estando relacionadas principalmente ao erro na utilização da técnica ou falta de conhecimento pelos profissionais, por isso, por meio de uma revisão bibliográfica, foi realizado um levantamento dos principais efeitos adversos ao utilizar toxina botulínica, assim como formas de prevenção e tratamento, obtendo-se muitos relatos de Ptose Palpebral após a aplicação desse ativo em pacientes.