bluuebunny/crossref_metadata_2025 huggingface dataset:
Exploring Riboflavin Quantification in Honey via Spectrofluorimetry: A Statistical Examination of Influential Extrinsic Variables
Authors: Khan Shahab , Khan Maaz , Hameed Ur Rahman  , AbdelGawwwad Mohamed Ragab , Elsadek Mohamed Farouk
Published: October 2024

Background:

The present study is focused on the collection of honey samples from the
different geographical and climatic conditions of Khyber Pakhtunkhwa and analyzing them for the
determination of riboflavin. Quantification of riboflavin, being natively fluorescent, was accomplished
using spectrofluorimetric method. Riboflavin has characteristic fluorescence spectra with
maximum excitation at 464 nm followed by an emission peak at 525 nm.

Method:

The procedure followed in this work comprised the construction of a calibration curve by
plotting the fluorescence intensity of a series of riboflavin solutions versus concentration. This curve
was used for the quantification of riboflavin in the collected honey samples. The effect of several
external factors such as the altitude of the sampling area, type of honey bee, type of flowers from
which the nectar was collected, and sampling season on the concentration of riboflavin in the honey
samples was statistically evaluated.

Results and Discussion:

It was concluded that the samples collected from lower altitudes have high
concentrations (1.156±0.08 μg g-1) of riboflavin. Similarly, the samples collected in autumn were
found to have a maximum average riboflavin concentration of 1.37±0.06 μg g-1, which was higher in
comparison to the samples collected in other seasons of the year. Likewise, the effect of flora on the
concentration of riboflavin was also investigated and it was found that honey samples collected from
areas where the nectar was collected from Ziziphus contains maximum riboflavin concentration averaged
at 1.383±0.1 μg g-1.

Conclusion:

Based on the size of the honey bees, the samples collected from hives of small honey
bees were found to have a maximum riboflavin concentration of 1.176±0.07 μg g-1. This study suggests
that besides the studied vitamin, the rest of the vitamins and other nutritional components may
vary in the honey samples depending upon external factors.

conclusion:

It was concluded that the samples collected from lower altitudes have high concentration (1.156±0.08 μg g-1) of riboflavin. Similarly, the samples collected in autumn were found to have a with a maximum average riboflavin concentration of 1.37±0.06 μg g-1, which was higher in comparison to the samples collected in other seasons of the year. Likewise, the effect of flora on the concentration of riboflavin was also investigated and it was found that honey samples collected from areas where the nectar was collected from Ziziphus contains maximum riboflavin concentration averaged at 1.383±0.1 μg g-1. Based on the size of the honey bees the samples collected from hives of small honey bees were found to have maximum riboflavin concentration of 1.176±0.07 μg g-1. This study suggests that beside the studied vitamin, the rest of the vitamins and other nutritional components may vary in the honey samples depending upon external factors.
Enzymeless Gabapentin Sensor Based on Prussian Blue-modified Indium Tin Oxide Electrodes for Sensing Gabapentin in Capsules
Authors: Alshitari Wael , El-Said Waleed A.
Published: October 2024

Background:

In this study, we reported on developing a susceptible, accurate, simple, and
economical electrochemical sensor for gabapentin determination in capsules.

Methods:

The ITO electrode was modified with a layer of Prussian blue nanoparticles and then used
as the working electrode. Gabapentin was extracted from commercial capsules, and a series of
concentrations of gabapentin were prepared for studying the efficacy of the proposed sensor. The
electrochemical measurements were performed using cyclic voltammetry and square wave
voltammetry techniques.

Results:

The sensitivity and selectivity of the developed electrode toward gabapentin in different
interferences, including citric acid, glucose, and urea, were investigated. The modified electrode
showed detection and quantification limits of 31.58 and 94.74 nM, respectively, over a dynamic
range of concentrations from 100 nM to 3 μM.

Conclusion:

The proposed sensor displayed a high sensitivity and selectivity for monitoring
gabapentin in pharmaceutical drugs without a noticeable interference. Hence, the modified electrodes
are great candidates for gabapentin routine analysis.
The Antifungal Effects of Hypericum perforatum Nanoemulsion against Candida albicans
Authors: Panahi Yasna , Yasamineh Neda , Memar Mohammad Yousef , Esmaeilzadeh Mahdiyeh , Zandesh Amir , Dizaj Solmaz Maleki
Published: October 2024

Background

Oral stomatitis is one of the common infections related to dentures (complete or partial), which is seen in the form of diffuse inflammation, mainly with Candida albicans. The aim of the present study was to investigate the antifungal effects of Hypericum perforatum nanoemulsion against Candida albicans.

Materials and Methods

The microdilution technique has been used in order to determine the antifungal effects of Hypericum perforatum nanoemulsion. The study has involved four groups: Hypericum perforatum oil, Hypericum perforatum nanoemulsion, distilled water as a negative control, and nystatin as a positive control. The first concentration of nanoemulsion in which no clear fungal growth was observed in the culture medium has been considered as the Minimum Inhibitory Concentration (MIC) and the first concentration in which the fungal growth was completely stopped and no fungal growth was observed in the culture medium has been considered as the Minimum Fungicide Concentration (MFC). One-way Analysis of Variance (ANOVA) has been employed to compare the results between the groups. Tukey's post-hoc test has been used to make comparisons between the groups. The significance level has been considered at less than 0.05.

Results

Both Hypericum perforatum oil and Hypericum perforatum nanoemulsion have been found to exhibit good antifungal activity against Candida albicans. The MIC and the MFC of the nanoemulsion form have been found to be lower than the non-nanoemulsion form (P<0.05). Among the studied groups, the nystatin group had been found to have the best effect (P<0.05).

Conclusion

Considering the different antifungal mechanisms and also the different resistance mechanisms of nystatin and Hypericum perforatum nanoemulsion, the prepared nanoemulsion can be used to treat and reduce the population of nystatin-resistant Candida albicans strain. However, the efficiency of these materials needs to be confirmed in larger studies on resistant strains.
Social and Psychological Rehabilitation of Servicemen with Post-Traumatic Stress Disorder
Authors: Druz Oleh , Bursa Andrii , Dolynskyi Roman , Shpak Svitlana , Rudakevych Oksana
Published: October 2024

Introduction

The growing number of servicemen injured during the war in Ukraine creates a need for effective social and psychological rehabilitation and the identification of early signs of Post-Traumatic Stress Disorder (PTSD).

Aims

The aim of the study is to identify the need for psychological support for the rehabilitation of servicemen with PTSD.

Methods

The study employed the Primary Care PTSD Screen (Screen PC-PTSD), the Impact of Event Scale-Revised (IES-R), the 36-Item Short Form Health Survey (SF-36), and the Rogers-Diamond Socio-psychological Adaptation Test. The statistics were processed using descriptive statistics, analysis of variance, and regression analysis.

Results

This study reported that 29.65% of the servicemen showed signs of PTSD and observed symptoms of intrusion, avoidance, and hyperarousal. It was established that PTSD symptoms reduced the indicators of physical (R2=0.634, p<0.001) and psychological (R2=0.607, p<0.001) components of the quality of life of the servicemen, as well as socio-psychological adaptation (R2=0.576, p<0.001).

Conclusion

Among the studied servicemen, almost 30% demonstrated signs of PTSD, emphasizing the relevance of the studied problem. The identified negative impact of PTSD on the quality of life of the servicemen proved the importance of their complex social and psychological rehabilitation, involving the use of specific means at each stage. The obtained results can be used in the development of an algorithm for providing socio-psychological assistance to servicemen with signs of PTSD.
Nicotinamide Adenine Dinucleotide (NAD)-Dependent Protein Deacetylase, Sirtuin, as a Biomarker of Healthy Life Expectancy: A Mini-Review
Authors: Sugishita Yodo , Suzuki-Takahashi Yuki , Yudoh Kazuo
Published: October 2024

Although a variety of disease-specific biomarkers have been identified for common
lifestyle- or aging-related diseases, there are currently no indices available to measure general
health or the existence of pre-symptomatic conditions in various types of tissue and organ damage.
A rising body of research suggests that sirtuins may have the potential to be used as an index
to assess overall health status and the existence of pre-symptomatic illness states. Sirtuins (SIRTs)
are nicotinamide adenine dinucleotide (NAD)-dependent deacetylases expressed in a variety of human
somatic cells both in health and disease conditions. The activity and expression of SIRTs affect
important metabolic pathways, such as cell survival, senescence, proliferation, energy production,
stress tolerance, DNA repair, and apoptosis, thereby closely linked to aging and longevity.
Given the broad significance of SIRTs in physiological function maintenance, their activity in somatic
cells may reflect the early cross-sectional status of tissue damage caused by aging or systemic
inflammatory responses that are too early to be detected by disease-specific biomarkers. In
this mini-review, we discuss the utility of SIRTs as a surrogate clinical biomarker for health status
to evaluate and monitor health life expectancy and the presence of pre-symptomatic illness states.
Novel Delivery Systems of Raloxifene Hydrochloride for Improved Bioavailability and Therapeutic Efficacy: A Review
Authors: Chaturvedi Shashank , Sharma Richa
Published: October 2024

Raloxifene hydrochloride belongs to the selective estrogen receptor modulator category.
Initially, US FDA approved its use for the prevention and treatment of osteoporosis in postmenopausal
women. Later, raloxifene hydrochloride was also approved for the prevention of invasive
breast carcinoma in post-menopausal women under the high-risk category. Despite its immense
and diverse therapeutic potential, the oral bioavailability of raloxifene hydrochloride is only
~ 2%. The factors responsible for the poor bioavailability of raloxifene hydrochloride include
its amphiphobic nature, para-glycoprotein pump-mediated efflux in the intestine, and high pre-systemic
glucuronidation. In the past two decades, multiple novel delivery systems, viz. lipid-based
nanocarriers, polymeric nanoparticles, polymer-lipid hybrid nanoparticles, micelles, and mixed micelles,
have been developed to overcome its drawbacks. Moreover, inclusion complex, phospholipid
complex, and solid dispersion have also been developed to improve its solubility and dissolution
rate. Further, some research groups successfully explored non-peroral routes like nasal and
transdermal for augmenting the raloxifene hydrochloride bioavailability and its therapeutic efficacy.
Hence, the principal objective of this review paper is to critically analyze all the delivery systems
developed for raloxifene hydrochloride with their advantages and limitations. In addition, a
detailed discussion of the physicochemical and pharmacokinetic parameters of raloxifene hydrochloride
has been included in this paper. An in-depth understanding of these parameters will assist
formulation scientists in developing efficient delivery systems in the future. In conclusion, the
literature review revealed that the nanoparticulate systems successfully augmented the raloxifene
hydrochloride bioavailability and therapeutic efficacy in pre-clinical experiments. However, future
clinical trials should be conducted to assess their safety and therapeutic efficacy for rapid preclinical
to clinical translation.
Milestones in the Technology of Modified Starch in Pharmaceutical Formulation
Authors: Agnihotri Jaya Anil
Published: October 2024

Carbohydrates, the most prevalent class of organic substances in living systems, play a
variety of important roles, such as in the creation of energy, the construction of biological structures,
and the synthesis of paper and food. More advanced uses of modified starch have been introduced
over the past millennium, demonstrating that modified starches are promising excipients in drug
delivery, an area in which their role and range of utility continuously increase. Technological
advancements in the pharmaceutical field have led to the development of new and highly stable
molecules with enhanced properties for novel drug delivery systems. Innovative starches from
various sources present exclusive support in the development of novel dosage forms.
Exploring the Efficacy of Convalescent Plasma Therapy in COVID-19 Patients: A Clinical Trial Study
Authors: Mahi-Birjand Motahareh , Ziaee Masood , Alemzadeh Effat , Barkhordari Amin , Azarkar Zohreh , Ebrahimzadeh Azadeh , Abedi Farshid , Azarkar Ghodsiyeh
Published: October 2024

Background:

In December 2019, a group of patients in Wuhan, Hubei province, China,
presented with severe illness and pneumonia of unknown origin. Subsequently, a novel coronavirus
was identified as the cause and named "2019 novel coronavirus" (2019-nCoV), later defined as
"SARS-CoV-2" (Severe Acute Respiratory Syndrome Coronavirus-2), leading to the development of
the disease known as COVID-19. This study aimed to evaluate the effectiveness and safety of convalescent
plasma as a potential therapy for patients with COVID-19.

Methods:

Patients diagnosed with COVID-19 based on real-time polymerase chain reaction (PCR)
or CT-Scan symptoms were randomly assigned to either the treatment group (n = 29, received convalescent
plasma) or the control group (n = 29). Clinical manifestations and pulmonary involvement
were monitored three times during the study. At the end of the intervention, patients were evaluated
for clinical symptoms, laboratory test results, and length of hospital stay.

Results:

Among the 58 patients who completed the study, there were no significant differences in
baseline characteristics between the treatment and control groups upon admission to the hospital.
However, the length of hospital stay was significantly shorter (9.54 days) in the convalescent plasma
group compared to the control group (12.88 days).

Conclusion:

The findings from this study indicate that the use of convalescent plasma therapy, in
addition to standard treatment, did not result in reduced mortality or improved clinical outcomes at
day 7 when compared to a placebo or control group.
Current State of Scientific Knowledge on Curcumin Encapsulation and Applications
Authors: Zam Wissam , Zahi Mohamed Reda , EL Hattab Mohamed
Published: October 2024

The yellow pigment curcumin has long been used in traditional medicine for its anti-inflammatory, antibacterial and antioxidant activities. Over the past half-century, scien-tific investigations have shown that curcumin is endowed with additional health benefits be-cause it can modify key molecular targets associated with a number of pathologies, such as diabetes, cancer, and arthritis, in addition to cardiovascular, multiple sclerosis, Alzheimer's, and Crohn's diseases. However, this molecule has several disadvantages, such as low bioavail-ability and solubility, severe oxidative destruction, light sensitivity, fast systemic clearance and breakdown at alkaline pH levels. To address these drawbacks, several methods of micro-encapsulation employing a variety of shell materials have been investigated. These techniques contributed toward the increase of curcumin's solubility and stability against heat, light, oxy-gen, and an alkaline pH. The various shell materials and methods used to microencapsulate this chemical are the main topics of this review. The use of microencapsulated curcumin in food, medicine, and cosmetics is also discussed in more detail. Recent relevant research from the last few years has been given in this area, along with future difficulties.
Ana Magalhães Rodrigues (1869-1937): A Descoberta de Uma Fotógrafa Portuguesa.
Authors: Resende Nuno
Published: October 2024

Gender studies are, in the historiography of art in Portugal, incipient and, as far as the History of Photography is concerned, still embrionary. However, several names of women who dedicated themselves to photography as amateurs are already known, many of them associated to their father, brothers or husband, following a similar tradition of female contribution to the artistic world, before the 19th century. Professional Portuguese photographer, self-designated the first, the name of Maria Reya Campos is known, operating in the south of Portugal. The circumstance of having identified, in 2019, a carte-de-visite with the label ANNA MAGALHÃES RODRIGUES, opened a new path for the study of the life and path of a woman-photographer working alone in the Portuguese countryside, in the early years of the 20th century. Based on written historical sources, photographs and a set of illustrated postcards, we developed some interpretations about her formation and trade.
Pensar a Fotografia como Performance. Notas preambulares para uma proposta metodológica.
Authors: Figueiredo Filipe , Chiarelli Cosimo
Published: October 2024

Photographing the theatre performance represents a significant theoretical challenge for reflection on photography, as it makes explicit a series of knots and tensions underlying its own language and ontology, namely the notions of document/interpretation, index/icon, presence/absence, instant/duration. Furthermore, theatre photography questions the meaning of the direct experience of performance, of liveness and its mediation. Based on the analysis of some examples, this presentation proposes to frame these tensions in the light of different performance theories, such as Austin's performative enunciations, or Ficher-Lichte's aesthetics of the performative. Thinking of Photography as Performance allows us to contribute to the development of a coherent and original hermeneutic grid that is potentially fruitful also for the general theory of photography itself.
Photomechanical crossroads - Comparing 19th-Century Chromocupography and Charles Eckstein’s method from a Printmaker’s Perspective
Authors: Lopes David , Machado Graciela
Published: October 2024

Chromocupography is a photo-etching technique developed in 19th-century Portugal under the supervision of chemist José Júlio Rodrigues (1843-1923). Very scarce literature is associated with the process, and it doesn’t seem to have been widely used after being made public. At the time, the technique was presented as a variant of Charles Eckstein’s (1840-1913) method, working in Hague, Holland. Eckstein’s technique consisted of hatching the lithograph stone with very fine delicate multiple-point needles to produce tone variations. Chromocupography substitutes the stone for a copper plate and the needles for a special coating with resin, thus creating a granular reservation protecting the metal from the etching bath.With this paper, we aim to present how the technical entanglements which are felt from a practical experience of the contemporary printmaker. We will be showing the various results we obtained conducting research following the descriptions found in literature around the subject of Portuguese process chromocupography, at the Faculty of Fine Arts of the University of Porto within the project of Pure Print Archaeology (i2ADS/FBAUP)
Incorporation of Calcimimetics into End-Stage Kidney Disease Bundle
Authors: Karaboyas Angelo , Zhao Junhui , Ma Junjie , Moore Carol , Saleem Najma , Martin Kevin J. , Sprague Stuart M. , Smerdon Caroline , Pecoits-Filho Roberto , Pisoni Ronald L
Published: October 2024

Key Points

After incorporation into the bundle in 2021, etelcalcetide use decreased substantially, reflecting financial incentives to restrict access.

Etelcalcetide discontinuers had a swift and sustained increase in parathyroid hormone and loss of secondary hyperparathyroidism control, despite most switching to cinacalcet.

These findings have US policy implications not only for etelcalcetide and parathyroid hormone but also for future development of innovative therapies in dialysis.

Background

Calcimimetics, including intravenous etelcalcetide and oral cinacalcet, are often prescribed to hemodialysis patients to prevent complications of elevated parathyroid hormone (PTH) levels. In January 2021, US dialysis reimbursement policy switched from the transitional drug add-on payment adjustment (TDAPA) to an increased bundled payment, with $10.09 per session added for all hemodialysis patients to cover the expense for calcimimetics, whether or not patients are administered etelcalcetide. We leveraged this natural experiment to investigate the effect of this policy change.

Methods

This analysis included 713 US in-center hemodialysis patients enrolled in the United States Dialysis Outcomes and Practice Patterns Study who discontinued etelcalcetide during the TDAPA transition period (December 2020–April 2021). Within a self-matched longitudinal design, within-patient changes in mean PTH, calcium, and phosphorus were assessed in the 6 months before versus after etelcalcetide discontinuation, using linear regression adjusted for potential confounders.

Results

Etelcalcetide use in the United States Dialysis Outcomes and Practice Patterns Study decreased by 58%, from 12% to 5% from July 2020 to 2021; 73% of etelcalcetide discontinuers switched to cinacalcet within 6 months. Comparing the 6 months before versus after etelcalcetide discontinuation, the mean PTH levels increased by 107 (95% CI; 80 to 133) pg/ml, and the prevalence of PTH >600 pg/ml increased by 15% (95% CI; 11% to 19%), from 28% to 43% overall, and increased from 26% to 49% among Black patients. The mean serum calcium and phosphorus levels increased by 0.42 and 0.16 mg/dl, respectively.

Conclusions

Etelcalcetide use decreased substantially after TDAPA ended in January 2021, with most patients switching to cinacalcet. The subsequent increase in PTH levels was swift and sustained and especially pronounced among Black patients, raising concerns about disparities and potential downstream effects on clinical outcomes. Despite the spirit of the policy change, the flat per-treatment increased payment may have inadvertently created a financial incentive to restrict patient access to a more effective therapy and potentially stifle drug innovation.
Research on the English Translation Standards of Foshan Cantonese Opera Classics
Authors: Wang Dong , Cao Guangtao
Published: October 2024

As the birthplace of Cantonese opera, Foshan takes the lead in the inheritance, protection, and development of Cantonese opera. Foshan has invested heavily in the development, inheritance, and promotion of Cantonese opera, and has made great efforts. Nowadays, Cantonese opera is flourishing in various organizational forms in the settlements of overseas Chinese around the world, and is very popular among local Chinese and foreign people. Foshan Cantonese opera needs to vigorously promote the translation and dissemination of Cantonese opera to the outside world. In the translation of Foshan Cantonese opera classics, translators should take "conveying essence and meaning" as the overall guiding principle.
Does Coproduction Enhance Quality of Public Infrastructure?
Authors: Katunze Miriam , Voon Jan P.
Published: October 2024

Coproduction is viewed in this paper as joint effort or cooperation between citizens and public infrastructure service providers. There is a paucity of studies on the impact of coproduction on public infrastructure quality or performance. Poor public infrastructure development poses a financial burden to many developing countries. In this paper, we use road maintenance as the example of public infrastructure. Using the Afro-barometer wave-6 dataset on Uganda, we develop the appropriate coproduction indexes as well as the road maintenance performance indexes from the survey data. Our results show that coproduction has significantly positive impacts on public road maintenance performance (RMP), which raises social welfare and economic development. Our results are robust to various model specifications and the conclusions remain valid after controlling for any potential endogenous influence or reverse causality problem that might arise. Our analysis points to the practical importance of cooperation between community and government in transport infrastructure provision such as road maintenance. It also provides practical implications for policy makers on how coproduction between community and government could be arranged.
Research on the Talent Cultivation Model of Accounting and Finance Professionals in Higher Vocational Education under the Background of MOOCs
Authors: Xu Yihua
Published: October 2024

In the era of big data, higher education institutions need to keep up with the development trend, gradually optimize and improve teaching methods, and realize the organic combination of teaching and technology. Higher vocational colleges should take the initiative to integrate science and technology into teaching practice and promote the organic combination of science and technology and education. Moocs, as a typical representative of the integration of science and technology and education, should keep up with the trend of The Times. Through in-depth research on the advantages of MOOCs for the teaching of finance and accounting major, the problems of integrating MOOCs into teaching are analyzed, and then targeted and operable countermeasures are put forward.
Ficoteca del Herbario de la Universidad de Sonora: una contribución al estudio de las macroalgas y los ecosistemas marinos del noroeste del país.
Authors: Ponce-Manjarrez Erick José , Urquidez-Bejarano Perla , Sandoval-Ortega Manuel Higinio
Published: October 2024

Las ficotecas son colecciones científicas indispensables para el estudio y conservación de los ambientes acuáticos, ya que permiten tener un registro de la presencia, distribución y diversidad de algas macroscópicas. En octubre de 2022 se inauguró la Ficoteca del Herbario USON, de la Universidad de Sonora, una colección seca de macroalgas. La colección incluirá principalmente ejemplares provenientes del Golfo de California, en especial del litoral sonorense. La Ficoteca del Herbario USON inicia con 76 ejemplares de nueve familias, 11 géneros y 16 especies de macroalgas resultado de la primera etapa del proyecto USO313008046. Con la apertura de esta nueva colección se contribuye al estudio de los recursos marinos del estado de Sonora, cuya costa ha sido poco explotada en materia de macroalgas, y al conocimiento del patrimonio natural de la nación.
Citar a las autoridades y años de publicación en los taxones algales. Pose, costumbre o razón fundada.
Authors: F. Pedroche Francisco , Novelo Eberto
Published: October 2024

El mencionar a las autoridades y años de publicación, como parte de los taxones que se señalan en una publicación, parece ser una norma que los autores siguen por costumbre o por la imposición de las normas editoriales de las publicaciones. ¿Cuál es el significado e importancia que estos tienen y la forma correcta de citarlos? En la presente contribución y como una buena práctica, explicamos y sugerimos el uso correcto y adecuado de los componentes de un nombre científico en algas y la intención que tiene el agregar a este nombre la fecha de publicación de su descripción. Ambos descriptores tienen como función remitir al investigador a la circunscripción que define y delimita a cada taxón, fundamento para una acertada identificación.
Mining Enterprise Production Line Optimal Load Modelling
Authors: Blagodatsky G. A. , Borisov V. N. , Gorokhov M. M.
Published: October 2024

The article is devoted to the issues of the mining enterprise production line optimal load model. A large number of issues to related to alternative production plan implementation transition are considered in various works. A mathematical model to form an optimal plan mining enterprise raw material mixture from deposits is proposed in the study. A method of multi-criteria alternative ranking in terms of integral efficiency indicator with the following problem solution of optimal plan determination for a raw material mixture from deposits was chosen for that purpose. The article proposes an approach to determine the production line optimal loading plan of a mining enterprise based on the creation of an ore mixture with the highest utility. The value of a particular deposit is determined by a variety of factors, including the distance from the production line, the ore content in the rock, and the volume of the deposit. The paper shows that the development of a specified field management can be implemented based on solving linear programming problems. The hierarchy contains three levels: the system purpose; the factors influencing the deposit appeal (the metal content, the deposit volume, and transport accessibility); alternatives (deposits of raw materials directly). Let's assume that it is necessary to find the maximum efficiency by means of an ore mixture from the given deposits. Resource restrictions are imposed on the task: the work and machine time fund, the amount of first type reagent, and the amount of second type reagent. The composition of the constraint vector can be set depending on the value of the resources. The study found that the optimal plan is implemented under the complete resource utilization both of the first and the second types and a fifty-three percent level of the third resource utilization. Despite the low integral assessment of the raw material value of the fourth deposit, which is mainly determined by the low ore content in the rock, with respect to other deposits, its maximum utilization is also recommended, which in turn, is determined by the low resource intensity of ore extraction from this rock.
Wind Power Station Efficiency Increase Methods Based on Wind Turbine Condition Process Mathematical Modelling when Distributing Electric Power Between the Consumers in Arctic and Far North Regions
Authors: Buyalsky V. I.
Published: October 2024

The relevance of wind power plant efficient control method based on wind turbine condition process mathematical modeling is proved for electric power distribution between consumers, intended to minimize decision-making time on technological process redistribution of electric power production for another consumer by means of actual information on equipment failure time (wind turbine, electric power stocking system), that provides optimum power production and consumption planning in northern regions. The review of the basic mathematical modeling methods of electric power redistribution between consumers that showed there are certain problem statements with insufficient descriptions of mathematical models or the absence of ready and effective methods to solve them, in particular, wind turbine condition process mathematical modeling for electric power distribution to consumers in northern regions. As a result of the analysis of wind power plant efficient control method on the basis of wind turbine condition process mathematical modeling to distribute electric power to consumers in northern regions game theory and pulse system functioning mathematical methods application based on difference equations is expedient. The decision-making strategies stipulated by 'nature' (working capacity or wind turbine failure), the scheduler (repair or wind turbine redistribution) and a condition of phase co-ordinate (repair, idle, redistribution or operation wind turbine modes) are defined. On the basis of the accepted strategy and use of step function Heaviside F(t) for fixing of technological process time, the description of the wind turbine condition equation was made providing operative failure time information access on because due to idle time, redistribution or repair that provides optimum electric power production planning for a consumer.
Information and Logic Model Development Natural Engineering System Environmental Monitoring
Authors: Gorokhov M. M. , Kurguzkin P. M.
Published: October 2024

Environmental monitoring is the main source of information on the current environment state and its changes associated with man-made and anthropogenic impact. The system of environmental monitoring of increased danger technogenic objects includes state observations of air and water environments, soil snow cover, as well as monitoring of flora and fauna, including biotesting and bioindication. An example of an integrated approach to organizing the environment conditionobserving system is environmental monitoring in the zone of chemical weapons destruction facilities. The results of monitoring activities are numerical arrays of quantitative indicators of the environment state related to specific monitoring objects: concentrations of pollutants in natural environments (air, water, and soil); indicators of the state of flora and fauna; bioindication results. The complexity of the monitoring result integrated analysis is primarily associated with the diversity of the structure and number of indicators for individual natural environments, different dimensions of indicators, as well as the sparseness of the matrices of data arrays. Taking into account the above-mentioned information, it is relevant to develop methods for storing and updating environmental monitoring data arrays, as well as algorithms for operational analysis of the results of monitoring studies. The paper presents an information and logical model that allows to form databases for storing and replenishing data on the state of the natural engineering system. The developed information and logic model is focused on building OLAP cubes for subsequent analysis of environmental monitoring data. The presented information and logical model is the main stage of developing a system for storing, updating and analyzing the results of environmental monitoring of the TCP. Systematization and structuring of indicators of natural environments and ecosystems makes it possible to formulate a number of practical tasks for assessing and predicting the state of the environment in the presence of technogenic impact.
Multi-criteria Model for Production Plan Management of a Machine-building Enterprise
Authors: Demyshev A. V. , Vologdin S. V.
Published: October 2024

The concept of developing an intelligent system to manage the planning of a manufacturing enterprise, and a description of the functionality and modules of the information system are given. In general, operational planning is a complex task of optimizing the construction of a production plan, which includes several criteria and faces various limitations. Multi-criteria is associated with the need for order fulfillment priority in accordance with the law, and the non-linearity of the task is due to technological limitations of production. One of the criteria is to maximize the fulfillment of contractual obligations to supply products to customers. Another criterion is to maximize profits from the sale of the entire range of manufactured products. The limitations in this task are the storage capacity, availability of raw materials and components, the time of operations, the workload of equipment and the priority of orders. Two approaches to solve the optimization problem of managing the production plan are considered, and block diagrams of the implementation of the proposed algorithms are provided. In the first approach, the initial problem is reduced to a combination of linear programming problems, for which the simplex method or the Gomori method are used in practice. A more effective approach to solving this extreme problem is the use of a genetic algorithm and its modifications. The scientific novelty of the conducted research lies in the systematic application of mathematical and computer modeling methods to build an optimal operational production plan. The experience of practical implementation of software systems confirms that intelligent production plan management systems are able to increase the efficiency of enterprise business proce sses, allowing organizations to plan production and allocate resources in market conditions optimally.
Optimization of the Colony Size Parameter in the Ant Algorithm for Solving the Routing Problem in Communication Networks
Authors: Mironov A.A. , Fayzullin R.V. , Kuzikova A.V.
Published: October 2024

With the increasing amount of information and complexity of communication networks, the issue of routing remains relevant. The routing problem is a classic problem of building a logical structure of a communication network. To solve this problem, many methods are used, such as: genetic algorithms, ant algorithm, swarm intelligence, artificial bee colony algorithm, firefly algorithm, bacterial food search optimization algorithm, etc. Despite the fact that the effectiveness of using the ant algorithm is widely known and described, however, there is no single approach to finding the optimal use case for the algorithm. There is a need to determine the optimal size of the colony when solving the routing problem. The article describes the results of the simulation process of modeling the behavior of ant colonies of different sizes to find the optimal route through the AnyLogic environment. It is determined that by means of simulation it is possible to reproduce the use of the ant algorithm to solve the routing problem in communication networks. To find the optimal ratio of the colony size to the complexity of the task, you can use the grid search methodology. The results clearly demonstrate that with increasing complexity of the task (the number of communication nodes), the same number of ants cope worse with the task. The problem associated with the need to accurately determine the optimal size of a colony is of great practical importance, because an increase in the size of a colony has generally decreasing utility. It was found that for many, an increase in the number of ants from 100 to 500 had a relatively greater effect than an increase in the size of the colony from 1000 to 10000. It is proved that by means of simulation it is possible to reproduce the use of the ant algorithm to solve the routing problem in communication networks.
Implementation of Software for Learning Message Transmission Using Morse Code
Authors: Arslanov I. A. , Pleshakov D. I. , Sidorina V. A. , Bogdanov A. A.
Published: October 2024

The article presents the implementation of software for training message transmission using Morse code. This is a method of sign coding when letters of the alphabet, numbers, punctuation marks and other symbols are represented as sequences of short and long signals called dots and dashes. It is intended for transmission over serial communication channels. A unique feature of Morse code is the ability to be encoded and decoded by humans without the use of special terminal devices. The paper shows a software implementation of processing input characters using a telegraphic key, it includes: various mathematical requirements and conditions that allow you adjusting to each user, provided that his input speed will either fall or remain unchanged. However, it is possible to adjust the minimum duration threshold in such a way that the system will slowly adapt to a slow increase in input speed. At the same time, the higher the value of the minimum threshold, the faster the adaptation is; however, it will fall within the limit of the maximum input speed that the device can recognize. During the implementation of the program, a flow chart of message transliteration, signal reception and transmission was developed. The whole program implements the following functions: a simple and intuitive translator, with audio output, a simulator for consolidating the skill of entering Morse code using a key; consolidating the skills of recognition and decoding by ear. To create the final application for training, the Processing toolkit was chosen, since its key parameter when choosing a development tool has a simple writing syntax to increase the speed of writing code, as well as the ability of the environment to work with the communication channel of the microcontroller.
Measurement of Oscillatory and Dissipative Resonator Characteristics of Solid-State Wave Gyroscopes: Algorithms for Operational Correction of Systematic Signal Drift
Authors: Shishakov K. V.
Published: October 2024

The article discusses the possibilities of increasing the output signal accuracy of integrating solid-state wave gyroscopes manufactured with a reduction in the requirements for the residual characteristics of the multi-frequency and multi-factor ratios of their resonators, as well as for the centering of the control ring electrode. These capabilities involve the use of a more complex output function that includes an additional part due to the effect of these errors on the systematic drift function. However, its formation requires introduction of an interval shutdown of the parametric excitation system so as to increase the purity of identification of the listed factors. To reveal this topic, the following is sequentially described: mathematical formulation of the problem; general analysis of the systematic drift of the integrating gyroscope signal caused by mechanical errors in the design of its resonator; autonomous algorithmic reduction of the influence of the dominant residual differentials in the mode of interval disconnection of excitation; autonomous algorithmic reduction of the influence of the dominant residual frequency difference in the mode of interval disconnection of excitation; simultaneous algorithmic compensation of the influence of residual Q and Frequency in the interval disconnection mode of excitation; estimation of the signal drift component of the integrating gyroscope, due to errors in the control loops, as well as the possibility of its reduction. The analysis of these problems is carried out on the basis of a model of wave processes in the gyroscope resonator, obtained only on the basis of the laws of classical mechanics. There were no additional errors due to the imperfection of the electrical circuits for processing measurement and control signals. Various computational schemes discussed in the article can also be useful for performing operational adjustments of the gyroscope measurement system, which may be required as a result of the design aging factor, as well as after its intensive use in a wide range of external disturbances.
On Digital Transformation Experience of the Order Fulfillment Process
Authors: Barsukov A. V. , Gorokhov M. M. , Korepanov A. V.
Published: October 2024

The paper examines the process of order execution being won on a tender platform. Due to the short order fulfillment deadline, the work starts not at the moment of contract signing, but at the moment of winning the tender. This leads to additional risks of non-fulfillment of the order and the emergence of unfinished production. In the conditions of stock exchange prices in commodity markets, the process of the production cost determination becomes a more complex task, requiring daily cost reevaluation with the integration of heterogeneous information systems. Therefore, a transition from automation to digital transformation is required. The literature review on the issue of manufacturing enterprise digital transformation has been completed at work. The differences between the definitions of digitalization, automation and digital transformation are described. The most promising technologies for digital transformation are outlined. Based on the reviewed literature, the main problems of digital transformation, including managerial issues highlighted by the authors as the most important, are identified. The operations of several enterprises within one information space are described, indicating the information systems used. The process of creating an order on a tender platform for the examined manufacturing enterprise is detailed, as well as a detailed description of order creation. The issue of production cost determination in the conditions of order execution start prior to contract signing is discussed. The pressing issue of digital development of an industrial enterprise due to the transition to new information systems is presented. The problems of using current information systems in production are described. The market analysis of modern Russian, foreign, and open-source systems with a description of the issues of their application is provided. A method for unfinished product automation in a new order is proposed.
Development and Manufacturing Method of Electrodes for a High Temperature Oxygen Sensor
Authors: Yurkov A.S. , Selivanov I.A. , Pletnev M.A.
Published: October 2024

The article discusses the use of zirconium dioxide stabilized with yttria as an electrolyte for the formation of a high-temperature ceramic oxygen concentration sensor. The fundamental possibility of using such a material is due to the high electrical conductivity caused by the mobility of oxygen ions in the vacancies of the solid electrolyte. The operating principle of such a sensor as an electrochemical concentration element is discussed. It has been shown that the use of such sensors is relevant for various industries (including chemical, metallurgical, oil and gas, energy and others). Options for forming electrodes of an electrochemical sensor using various materials and deposition methods are considered. A method for forming a platinum coating using a chemical method using isopropyl alcohol and subsequent pyrolysis was tested. It has been experimentally shown that the chemical method is applicable for the formation of electrodes of an electrochemical sensor. The electrical characteristics of the resulting coatings were measured. The optimal composition of the reaction mixture and the required number of layers to create a stable operating electrochemical sensor have been determined. The dependence of the potential of the formed electrochemical sensor from stabilized zirconium oxide on oxygen concentration in a wide temperature range has been studied. It has been shown that when using a scheme of sequential transformations, hydrolysis of platinum tetrachloride - deposition on a substrate - reductive pyrolysis, it is possible to obtain a high-quality conductive coating for the formation of gas sensor electrodes. The optimal composition of the reaction mixture for the formation of platinum electrodes has been selected. The optimal number of layers was determined to ensure the required level of electrical conductivity of the electrodes. It has been shown that an electrochemical element based on zirconium dioxide and platinum electrodes, formed according to the scheme developed in this work, can be used as a high-temperature oxygen sensor.