bluuebunny/crossref_metadata_2025 huggingface dataset:
Practical Recommendations for Exercise Training in Patients with Long COVID with or without Post-exertional Malaise: A Best Practice Proposal
Authors: Gloeckl Rainer , Zwick Ralf H. , Fürlinger Ulrich , Schneeberger Tessa , Leitl Daniela , Jarosch Inga , Behrends Uta , Scheibenbogen Carmen , Koczulla Andreas Rembert
Published: April 2024

People with long COVID may suffer from a wide range of ongoing symptoms including fatigue, exertional dyspnea, reduced exercise performance, and others. In particular, impaired exercise performance is a condition that can be recovered in many people through an individualized physical exercise training program. However, clinical experience has shown that the presence of post-exertional malaise (PEM) is a significant barrier to physical exercise training in people with long COVID. Currently, there is no guideline or consensus available on how to apply exercise training in this cohort. Therefore, we conducted a literature review in the PubMed library using the following search terms: “COVID”, “post-COVID”, “long COVID” and “exercise” searching for studies from January 2020 to January 2024. Data from 46 trials were included. Exercise training regimes were very heterogeneous and none of these studies reported on the management of PEM in the context of an exercise training program. Based on the feedback from an additional survey that was answered by 14 international experts in the field of exercise training in long COVID, combined with the authors´ own extensive practical experience, a best practice proposal for exercise training recommendations has been developed. This proposal differentiates exercise procedures according to the presence of no, mild/moderate or severe PEM in people with long COVID. These recommendations may guide allied healthcare professionals worldwide in initiating and adjusting exercise training programs for people with long COVID, stratified according to the presence and severity of PEM.
Determinants of puerperal sepsis among postpartum women at a tertiary care hospital in Ethiopia: an unmatched case-control study
Authors: Seboka Keraj , Gurara Abenet Menene , Bekele Nardos Tilahun , Belachwe Yohanes Abera , Getahun Mihiret Shawel , Negussie Yohannes Mekuria
Published: April 2024

Background

Puerperal sepsis, is a significant factor in maternal morbidity and mortality, especially in regions with lower income levels where maternal mortality rates are highest. However, it can be largely avoided if detected in time. Recognizing and dealing with the root causes early is essential in addressing this problem. Therefore, this study aimed to identify the determinants of puerperal sepsis among postpartum women at a tertiary care hospital in Ethiopia.

Methods

An institutional-based unmatched case-control study was conducted among 266 postpartum women (88 cases and 178 controls) from October 1, 2023 to November 30, 2023. For each case, two controls were chosen using a systematic random sampling approach. Data were collected using an interviewer-administered, structured questionnaire and medical record review. The collected data were entered into Epi Info version 7.2 and analyzed using SPSS version 27. Binary logistic regression analysis was used to model the association between puerperal sepsis and independent variables. variables that had a crude association in the bivariable analysis (p < 0.25) were entered and analyzed by a multivariable binary logistic regression model to identify statistically significant factors. In the final model, Adjusted odds ratios with their 95% confidence intervals were calculated to determine the strength of the association. Statistical significance was declared at p < 0.05.

Result

Rural residence (AOR = 6.9; 95% CI:2.77–17.10), having no formal education (AOR = 3.8; 95% CI: 2.55, 10.76), cesarean section delivery (AOR: 5.1; 95% CI: 1.30, 11.00) and complication during pregnancy (AOR: 4.6, 95% CI: 1.96, 11.10) were independent determinants of puerperal sepsis.

Conclusion

Place of residence, maternal education level, mode of delivery, and complication during pregnancy were determinants of puerperal sepsis. It is crucial to implement education and awareness initiatives aimed at mothers, ensure universal access to healthcare services, advocate for evidence-based delivery protocols, and conduct comprehensive antenatal screenings.
Dengue haemorrhagic fever in chronic kidney disease and heart failure: challenges in fluid management
Authors: Vidanapathirana Manudi
Published: April 2024

Dengue haemorrhagic fever (DHF) is recognized to have high mortality in patients with chronic kidney disease (CKD) and heart failure (HF). They are at high risk of shock during the ascending limb of the critical phase of DHF, fluid overload during convalescence and bleeding throughout the entire illness. Physiological changes and medications used in CKD/HF make the diagnosis and monitoring of DHF difficult. Treatment with standard fluid regimens also poses a challenge due to the propensity for fluid overload. As a result, standard dengue guidelines do not provide recommendations on fluid management regimens in DHF with CKD/HF. This article provides a narrative review on the existing evidence for management of DHF in patients with volume-changed states such as HF, CKD and nephrotic/ nephritic syndromes. It will explore the relevant diagnostic and therapeutic dilemmas, acknowledge the challenges for developing guidelines and recommend strategies to improve fluid management in these groups of patients.
Fluoroscopically calibrated 3D-printed patient-specific instruments improve the accuracy of osteotomy during bone tumor resection adjacent to joints
Authors: Wang Chen , Huang Siyi , Yu Yue , Liang Haijie , Wang Ruifeng , Tang Xiaodong , Ji Tao
Published: April 2024

Background

Inadequate surface matching, variation in the guide design, and soft tissue on the skeletal surface may make it difficult to accurately place the 3D-printed patient-specific instrument (PSI) exactly to the designated site, leading to decreased accuracy, or even errors. Consequently, we developed a novel 3D-printed PSI with fluoroscopy-guided positioning markers to enhance the accuracy of osteotomies in joint-preserving surgery. The current study was to compare whether the fluoroscopically calibrated PSI (FCPSI) can achieve better accuracy compared with freehand resection and conventional PSI (CPSI) resection.

Methods

Simulated joint-preserving surgery was conducted using nine synthetic left knee bone models. Osteotomies adjacent to the knee joint were designed to evaluate the accuracy at the epiphysis side. The experiment was divided into three groups: free-hand, conventional PSI (CPSI), and fluoroscopically Calibrated PSI (FCPSI). Post-resection CT scans were quantitatively analyzed. Analysis of variance (ANOVA) was used.

Result

FCPSI improved the resection accuracy significantly. The mean location accuracy is 2.66 mm for FCPSI compared to 6.36 mm (P < 0.001) for freehand resection and 4.58 mm (P = 0.012) for CPSI. The mean average distance is 1.27 mm compared to 2.99 mm (p < 0.001) and 2.11 mm (p = 0.049). The mean absolute angle is 2.16° compared to 8.50° (p < 0.001) and 5.54° (p = 0.021). The mean depth angle is 1.41° compared to 8.10° (p < 0.001) and 5.32° (p = 0.012). However, there were no significant differences in the front angle compared to the freehand resection group (P = 0.055) and CPSI (P = 0.599) group. The location accuracy observed with FCPSI was maintained at 4 mm, while CPSI and freehand resection exhibited a maximum deviation of 8 mm.

Conclusion

The fluoroscopically calibrated 3D-printed patient-specific instruments improve the accuracy of osteotomy during bone tumor resection adjacent to joint joints compared to conventional PSI and freehand resection. In conclusion, this novel 3D-printed PSI offers significant accuracy improvement in joint preserving surgery with a minimal increase in time and design costs.
Cholestatic liver injury secondary to over-the-counter cyproheptadine: case report and review of literature
Authors: Agarwal Ayush , Shastri Arpit , Ganesh C. P. , Shastri Malvika , Mitra Suvradeep , Ray Debadrita , De Arka
Published: April 2024

Background

Cyproheptadine is an easily available over-the-counter first-generation antihistaminic that is often used as an appetite stimulant. Although it is usually a safe drug, rare instances of drug-induced liver injury may occur.

Case presentation

We report a case of cholestatic liver injury secondary to cyproheptadine in a young pharmacy student with chronic hepatitis B and review the literature of cyproheptadine-induced liver injury.

Conclusion

Although cyproheptadine is largely a safe drug, its potential for significant liver toxicity cannot be ignored.
INTERNACIONALIZAÇÃO DE BIOJOIAS
Authors: Silva Givan Aparecido Fortuoso da , Martins Adriana de Souza , Oliveira Érica Santos , Silva Márcia Joviano da
Published: April 2024

Analisar se a sociobiodiversidade brasileira contribui para a inserção dos produtores de biojoias no mercado internacional corresponde ao objetivo geral deste estudo. Como objetivos específicos tem-se verificar quais fatores da sociobiodiversidade brasileira contribuem para agregação de valor para os produtores de biojoias ingressarem no mercado internacional; averiguar se a inserção das biojoias brasileiras no mercado internacional contribui para a formação de cadeias produtivas de interesses dos povos e das comunidades tradicionais e de agricultores familiares; e constatar se a produção de biojoias por povos e comunidades tradicionais colabora para a manifestação da cultura popular e de sua capacidade criativa.  A pesquisa qualitativa de caráter exploratório fez uso de um roteiro de entrevista para a coleta de dados. Os resultados demonstram que, mais que contribuir para a inserção das biojoias no mercado internacional, a sociobiodiversidade reiterou valores sociais, culturais e econômicos, ajudando na diversificação das peças e aumentando as oportunidades para os produtores.
PARADIGMATISMO OU MULTIPARADIGMATISMO, EIS A QUESTÃO? O DILEMA DO ESTUDANTE DE PÓS-GRADUAÇÃO NA PESQUISA ACADÊMICA EM ADMINISTRAÇÃO
Authors: Leal Janayna Souto , Firmino Thaís Teles , Mendes Josiete da Silva , Dantas Bruna Lourena de Lima
Published: April 2024

Neste ensaio, buscamos apresentar e refletir sobre os dilemas associados à escolha da natureza paradigmática ou multiparadigmática, considerando que esta caminhada pode significar uma expansão ou limitação para o estudante de pós-graduação no panorama da pesquisa acadêmica em Administração. Nesse sentido, propusemos que o cerne da questão deve ser a dissolução de estruturas restritivas, em particular as políticas, a fim de que o discente de pós-graduação possa definir e assumir suas escolhas teóricas e metodológicas a partir de sua bagagem acadêmica, profissional e pessoal. Com esta discussão, pretendemos o fomento de trabalhos que abordam e discutem a temática de maneira a compreender a realidade e os desafios do ambiente de pesquisa do estudante de pós-graduação na comunidade científica da Administração.
Η προληπτική εποπτική εξουσία της Τράπεζας της Ελλάδος (ΤτΕ) στο χρηματοπιστωτικό σύστημα
Authors: Τσιροβασίλη Αικατερίνη
Published: April 2024

Στην παρούσα εργασία θα αναλύσουμε τον εποπτικό ρόλο της Τράπεζας της Ελλάδος (εφεξής ΤτΕ) στον τομέα της μικροπροληπτικής εποπτείας και μακροπροληπτικής επίβλεψης στο χρηματοπιστωτικό σύστημα. Αρχικά θα ξεκινήσουμε με την ανάδειξη της σημασίας της ΤτΕ και γενικά των κεντρικών τραπεζών στη διαμόρφωση του τραπεζικού συστήματος. Εν συνεχεία θα αναφερθούμε γενικά στην δικαιολογητική βάση της ρυθμιστικής παρέμβασης κι εποπτείας στον χρηματοπιστωτικό τομέα της οικονομίας και ειδικά στην διαχρονική εποπτική δραστηριότητα της ΤτΕ πριν τη θεσμοθέτηση του Ενιαίου Ευρωπαϊκού Μηχανισμού-Ε.Ε.Μ. (Single Supervisory Mechanism-SSM). Κατόπιν, αφού εξηγήσουμε διεξοδικά τι είναι ο ως άνω μηχανισμός και πώς λειτουργεί, θα αναλύσουμε τον νέο ρόλο που καλείται πλέον να διαδραματίσει η ΤτΕ ως «εκτελεστικός βραχίονας» της Ευρωπαϊκής Κεντρικής Τράπεζας (Ε.Κ.Τ.) μετά την έναρξη λειτουργίας του μηχανισμού αυτού στον τομέα της προληπτικής εποπτείας και ρυθμιστικής παρέμβασης στη λειτουργία των πιστωτικών ιδρυμάτων (πι). Ακολούθως, θα αναλύσουμε την εποπτική αρμοδιότητα της ΤτΕ σε όλο το υπόλοιπο φάσμα του χρηματοπιστωτικού συστήματος, σύμφωνα με το άρθρο 55 Α του Καταστατικού της (χρηματοδοτικά ιδρύματα και ασφαλιστικό κλάδο). Μέσα από τις ανωτέρω αναλύσεις θα διαπιστώσουμε, ότι η ΤτΕ εξακολουθεί να είναι κυρίαρχη στον τομέα της προληπτικής εποπτείας και ρυθμιστικής παρέμβασης στη λειτουργία του χρηματοπιστωτικού συστήματος και μετά την εφαρμογή του Ε.Ε.Μ., διότι η δράση της εξακολουθεί να είναι καταλυτική όχι μόνο όταν δρά ανεξάρτητα, αλλά και όταν συνεργάζεται με την ΕΚΤ στα πλαίσια της λειτουργίας του ως άνω μηχανισμού.
Η σχέση της μουσικής με την ηθική και την πολιτική φιλοσοφία στον Πρόκλο
Authors: Μαρκέα Γεωργία
Published: April 2024

Η παρούσα έρευνα εστιάζει στον καίριο ρόλο που αποδίδει ο Πρόκλος στη μουσική ως παράγοντα ανάπτυξης των νέων. Εξετάζεται η άποψή του πως η μουσική, με τους ρυθμούς και τις αρμονίες της, μεταμορφώνεται σε πολιτικό θεσμό, με στόχο την καλλιέργεια της ψυχής και την ηθική βελτίωση. Η έρευνα έρχεται σε διάλογο με τις ιδέες του Keith Swanwick (1983) περί της μουσικής γνώσης, καταλήγοντας στο συμπέρασμα πως και οι δύο φιλόσοφοι θεωρούν τη μουσική θεμελιώδες στοιχείο στην ανάπτυξη του ατόμου. Ωστόσο, ο Πρόκλος εστιάζει στην κοινωνικοποίηση της μουσικής, με στόχο τη μεταφορά αξιών από τον συνθέτη στο κοινό. Ο Swanwick, από την άλλη, ερμηνεύει την ανάπτυξη μουσικής γνώσης ως ένα στάδιο που εκκινεί από τα Μουσικά Αγαθά ως Υλικά και φτάνει έως τις Ηθικές Αρετές ως Αξίες. Συμπερασματικά, η έρευνα υπογραμμίζει τον καθοριστικό ρόλο που διαδραματίζει η μουσική, σύμφωνα με τον Πρόκλο και τον Swanwick, στην ανάπτυξη του ατόμου και της κοινωνίας. Η ποιοτική μουσική, καλλιεργώντας την πνευματικότητα, την ηθική και τις αξίες, ενώνει παράλληλα τους ανθρώπους.
Isolation and complete genome sequence of Aeromonas bacteriophage Gekk3-15
Authors: Golomidova A.K. , Kulikov E.E. , Kuznetsov A.S. , Pechenov P. Yu. , Belalov I.S. , Letarov A.V. , Galyov E.E.
Published: April 2024

Bacteria of the genus Aeromonas, especially A. hydrophila and A. veronii are recognized as important fish pathogens that cause significant economic losses in aquaculture. Environmentally friendly bacteriophage-based solutions for the treatment of fish and for the reduction of colonization by pathogenic bacteria in production facilities are currently in high demand. The bacteriophage Gekk3-15 was isolated during a search for novel phage strains potentially suitable for Aeromonas biocontrol applications. Genome sequencing revealed that this virus is a relatively small myovirus with a 64847 bp long dsDNA genome, which is consistent with virion electron microscopy data. Bacteriophage Gekk3-15 is distinct in its nucleotide and encoded aa sequences from all other sequenced bacteriophage genomes, and may represent a new viral taxon at the genus or subfamily level.
Health care-seeking behavior for childhood illnesses in western Kenya: Qualitative findings from the Child Health and Mortality Prevention Surveillance (CHAMPS) Study
Authors: Ngere Sarah , Maixenchs Maria , Khagayi Sammy , Otieno Peter , Ochola Kennedy , Akoth Kelvin , Igunza Aggrey , Ochieng Benard , Onyango Dickens , Akelo Victor , Blevins John , Barr Beth A. Tippett
Published: April 2024

Background Child mortality in Kenya is 41 per 1,000 live births, despite extensive investment in maternal, newborn, and child health interventions. Caregivers’ health-seeking for childhood illness is an important determinant of child survival, and delayed healthcare is associated with high child mortality. We explore determinants of health-seeking decisions for childhood illnesses among caregivers in western Kenya. Methods We conducted a qualitative study of 88 community members between April 2017 and February 2018 using purposive sampling in an informal urban settlement in Kisumu County, and in rural Siaya County. Key informant interviews, semi-structured interviews and focus group discussions were performed. We adopted the Partners for Applied Social Sciences model focusing on factors that influence the decision-making process to seek healthcare for sick infants and children. The discussions were audio-recorded and transcribed. Data management was completed on Nvivo® software. Iterative analysis process was utilized and themes were identified and collated. Results Our findings reveal four thematic areas: Illness interpretation, the role of social relationship on illness recognition and response, medical pluralism and healthcare access. Participants reported some illnesses are caused by supernatural powers and some by biological factors, and that the illness etiology would determine the health-seeking pathway. It was common to seek consensus from respected community members on the diagnosis and therefore presumed cause and necessary treatment for a child’s illness. Medical pluralism was commonly practiced and caregivers would alternate between biomedicine and traditional medicine. Accessibility of healthcare may determine the health seeking pathway. Caregivers unable to afford biomedical care may choose traditional medicine as a cheaper alternative. Conclusion Health seeking behavior was driven by illness interpretation, financial cost associated with healthcare and advice from extended family and community. These findings enrich the perspectives of health education programs to develop health messages that address factors that hinder prompt health care seeking.
What is known from the existing literature about the treatment of Mallet Injury using 3D printed splints? A Scoping Review Protocol
Authors: Cronin Una M. , Shannon Alice , ó hAodha Micheal , O'Sullivan Aidan , Cummins Niamh M. , OSullivan Leonard
Published: April 2024

Background Mallet finger injuries are a frequent cause of hospital attendance, being the fifth most common injury in the body. They are therefore a frequent cause of hospital visits. To date, these injuries have primarily been managed using generic splints. As a generic splint provides a generic fit, patients who receive these are not provided with a custom splint experience. As the size and fit of these splints are not bespoke to the patient’s anatomy, patients may not always find the fit comfortable and may find complying with these splints difficult at times. However, an opportunity is developing within healthcare where custom splinting can be obtained for some using Three-D (3D) printing. The rationale for this review is to gain an understanding of the research that has been conducted on 3D printing of mallet injury splints. Objective The objective of this scoping review is to map the current literature on 3D printing associated with mallet finger injury. Methods The Joanna Briggs Institute (JBI) methodology for scoping reviews will be used throughout along with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR). Two researchers will search the databases that will include CINAHL, Embase, Cochrane, EbscoHost, Medline/Pubmed, Science Direct, Web of Science, and Google Scholar. The search will include grey literature and a hand search of sources falling outside the chosen databases. Screen titles, abstracts, and full-text articles will be reviewed by two researchers independently using Rayaan software. The data extracted from the literature will first be presented in a tabulated chart followed by a narrative synthesis. Registration The protocol was registered on 6th September 2023, with the Open Science Framework. Registration DOI: https://doi.org/10.17605/OSF.IO/FSJPK
Medical students’ knowledge on palliative care – a survey of teaching in Finland
Authors: Niemi-Murola Leila , Vanhanen Aija , Akrén Outi , Karihtala Peeter , Pöyhiä Reino
Published: April 2024

Background Most studies on palliative medicine (PM) undergraduate education have focused on contents and organizational issues but not the outcome. Students’ learning outcomes should be studied to improve teaching in medical schools. Methods A questionnaire about perceived PM education and attitudes on palliative care (PC) was sent to 543 last year students in all five Finnish medical schools in 2018–2019. In total, 175 (32 %) responses were received from four universities. The students evaluated both the quantity and quality of their PM teaching, implementation of European Association for Palliative Care (EAPC) guidelines and their satisfaction to the training. There were two palliative case scenarios, and the students were asked to find the best treatment option. Results In the Finnish universities, PM education was available mainly integrated with oncology, geriatrics, and general medicine. A total of two universities also offered a specific PM course. In average, 50–70% of the EAPC curriculum was covered by lectures, small-group teaching, seminars, and bedside teaching with significant differences between faculties. Only 30–60 % of students were satisfied with the education received. The highest rankings were given in the universities with a special PM course. Conclusions In Finland, the coverage of EAPC curriculum is satisfactory, but the PM education is mainly given integrated with other specialties. The dedicated course on PM was associated with increased perceived knowledge and satisfaction of PM education. However, PM training was not associated with students’ attitudes on PC.
Determination of ivermectin in plasma and whole blood using LC-MS/MS
Authors: Kaewkhao Natpapat , Hanpithakpong Warunee , Tarning Joel , Blessborn Daniel
Published: April 2024

Background Ivermectin is the most widely used drug for the treatment of helminthiasis worldwide, and it has also shown promise for malaria elimination through its potent mosquito-lethal activity. The objective of this study was to develop and validate a high-throughput and sensitive method to quantify ivermectin in plasma and whole blood samples, using automated sample extraction followed by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Methods Phospholipids were removed in patient whole blood (100 µl) and plasma (100 µl) samples using a 96-well plate Hybrid-solid phase extraction technique. Ivermectin and its isotope-labelled internal standard (ivermectin-D2) were separated on an Agilent Poroshell 120 EC-C18 50mm × 3.0mm I.D. 2.7µm, using a mobile phase of acetonitrile: ammonium formate 2 mM containing 0.5% formic acid (90: 10, v/v). Detection was performed using a triple quadrupole mass spectrometer in the positive ionization mode. Results The method was validated in the concentration range 0.970 - 384 ng/ml in both plasma and whole blood matrices. Intra- and inter-batch precisions during the validation were below 15%. There was no carryover or matrix effects detected. Ivermectin is a stable compound and results showed no degradation in the different stability tests. Conclusions The validated method proved to have high sensitivity and precision, good selectivity and to be suitable for clinical application or laboratory quantification of ivermectin in plasma or whole blood samples.
Mental capacity assessment in the multi-professional real world: a qualitative study of six areas of uncertainty
Authors: McWilliams Andrew , Ariyo Kevin , David Anthony S. , Owen Gareth S.
Published: April 2024

Background The Mental Capacity Act 2005 of England and Wales is a ground-breaking piece of legislation with reach into healthcare, social care and legal settings. Professionals have needed to develop skills to assess mental capacity and handle malign influence, but it is unclear how assessments are implemented in real world settings. Our previously reported survey found professionals juggling competing resources in complex systems, often struggling to stay up to date with law. The current follow-up study uses one-to-one interviews of professionals to characterise in detail six areas of uncertainty faced when assessing mental capacity, whilst suggesting ways to make improvements. Methods Forty-four healthcare, social care and legal professionals were interviewed, using a semi-structured topic guide. Transcripts were analysed using framework analysis: a qualitative technique built to investigate healthcare policy. Results Our topic guide generated 21 themes. In relation to the six areas of uncertainty: 1) Many participants stressed the importance of capturing a holistic view, adding that their own profession was best-placed for this - although a medical diagnosis was often needed. 2) The presumption of capacity was a laudable aim, though not always easy to operationalise and occasionally being open to abuse. 3) There was cautious interest in psychometric testing, providing a cognitive context for decisions. 4) Undue influence was infrequent, but remained under-emphasised in training. 5) Multi-professional assessments were common, despite doubts about fitting these within local resources and the law. 6) Remote assessment was generally acceptable, if inadequate for identifying coercion. Conclusions Practical constraints and competing demands were reported by professionals working within real world systems. Assessment processes must be versatile, equally applicable in routine and emergency settings, across diverse decisional types, for both generalist and specialist assessors, and able to handle coercion. Recognising these challenges will guide development of best practices in assessment and associated policy.
Wellcome’s 2019 funding for PhD programme training: An experiment in enhancing research culture
Authors: Carusi Annamaria
Published: April 2024

In September 2019, the results of Wellcome’s call for proposals for PhD training programmes were announced. This funding call was notable for making contributions to positive research culture as important a selection criterion as scientific excellence in PhD training. Aware that it’s intervention on enhancing research culture was experimental, Wellcome also commissioned work to reflect on its processes. I undertook two studies of the early phases of the funding call, of the Wellcome’s internal processes in shaping and implementing the call, and of the experiences and reflections of all applicants to the call. This Open Letter is a summary of the cross cutting themes of these two studies: the difficulties of defining positive research culture and of balancing it with scientific excellence; the expectation that supervision of PhD students is a key way to effect research culture change; the need for coherence between funding calls; issues around evaluating the track records of programmes on research culture, which further feed into defining the criteria of evaluation and selection relating to research culture.
The genome sequence of the Yellow-dotted Stilt, Euspilapteryx auroguttella Stephens, 1835
Authors: Boyes Douglas , Lees David C. , Sims Ian , Phillips Dominic , Boyes Clare ,   University of Oxford and Wytham Woods Genome Acquisition Lab,   Natural History Museum Genome Acquisition Lab,   Darwin Tree of Life Barcoding collective,   Wellcome Sanger Institute Tree of Life Management, Samples and Laboratory team,   Wellcome Sanger Institute Scientific Operations: Sequencing Operations,   Wellcome Sanger Institute Tree of Life Core Informatics team,   Tree of Life Core Informatics collective,   Darwin Tree of Life Consortium
Published: April 2024

We present a genome assembly from an individual male Euspilapteryx auroguttella (the Yellow-dotted Stilt; Arthropoda; Insecta; Lepidoptera; Gracillariidae). The genome sequence is 331.9 megabases in span. Most of the assembly is scaffolded into 30 chromosomal pseudomolecules, including the Z sex chromosome. The mitochondrial genome has also been assembled and is 16.94 kilobases in length.
ANALYSIS OF CONSUMER PREFERENCES AND THEIR INFLUENCE ON THE USE OF HOMEOPATHIC MEDICINES IN THE COMPLEX TREATMENT OF ACUTE RESPIRATORY VIRAL INFECTIONS
Authors: Zurnadjyants Yulia A. , Krasnova Anastasia S. , Medyannikova Alina I.
Published: April 2024

This article is devoted to the analysis of consumer preferences in the context of treatment of acute respiratory viral infections (ARVI) using homeopathic medicines. The study covers various aspects such as patients' main motivations for choosing homeopathy, their level of satisfaction with the results of treatment, and factors influencing the use of homeopathic remedies in complex therapy. The authors of the article review data from social surveys conducted on Google Forms portal, medical research, and literature reviews to provide a comprehensive overview of current trends in the use of homeopathic remedies in the treatment of acute respiratory infections. Special attention is paid to the influence of sociocultural and educational factors on patients' decision-making regarding treatment choices.
The results of the study may be useful for health professionals, pharmacists and public health organizations, helping to better understand consumer preferences for homeopathy and to develop individualized approaches to the treatment of acute respiratory infections.
The aim of the study is to analyse consumer preferences in the use of homeopathic medicines in the complex treatment of acute respiratory viral infections.
Materials:

Questionnaires and Surveys: Development of structured questionnaires to collect information from patients about their preferences, motivations and experiences of using homeopathic medicines for ARVI. The survey was conducted anonymously on Google Forms platform, which allowed systematisation of the data obtained.
Internet resources: Analysis of discussions and reviews on medical forums and social networks related to homeopathy and treatment of acute respiratory infections.

Methods:

Statistical analysis: Processing data from questionnaires using statistical techniques such as frequency and correlation analyses.
Qualified interviews: Conducting interviews with patients, doctors to gain a deeper understanding of motivations and experiences of using homeopathic medicines.
Systematic literature review: Examining existing scientific articles and publications related to homeopathy and ARVI to obtain additional data and context.
Comparative analysis: Comparison of questionnaire results with literature review and interviews to identify trends and influence of consumer preferences on the use of homeopathic medicines.

Results. The study found that homeopathic medicines have the potential to be in demand in the comprehensive treatment of acute respiratory infections.
Scope of the findings: the results of the study may be useful for health professionals, pharmacists and public health organisations, helping to better understand consumer preferences for homeopathy and to develop individualised approaches to the treatment of ARVI.
Orbis imagines ¿un reto de investigación conseguido?.
Authors: Escalera Pérez Reyes
Published: April 2024

En diciembre de 2022 el proyecto “Tres siglos de historia del grabado (XVI-XVIII): estampa y cultura visual en Andalucía y su impacto en el Nuevo Mundo. Nuevos enfoques” organizó en la Facultad de Turismo y Ciencias de la Educación de la Universidad de Málaga el Seminario Internacional: La vida en estampas. El grabado en Andalucía en la Edad Moderna y su influencia en América. En el mismo se presentaron diversos estudios –varios de ellos se publican en este monográfico- que abarcan una amplia variedad de temáticas en relación con el arte gráfico producido en Andalucía en la Edad Moderna, así como la traslación a América de advocaciones particulares a través de estampas andaluzas. Esta es una de las actividades científicas derivadas del proyecto, que se ha complementado con publicaciones y conferencias que se compilan en este texto.
Gobierno corporativo y administración financiera en las instituciones de educación superior
Authors: Mariño-Arévalo Andrés , Useche Alejandro J.
Published: April 2024

En este capítulo se analizan aspectos financieros y de gobierno corporativo propios de las instituciones de educación superior, las cuales, a pesar de ser comúnmente clasificadas como entidades de beneficio común y sin ánimo de lucro, son organizaciones que cuentan con estructuras y prácticas similares a aquellas del campo corporativo. Dichas instituciones deben, de igual manera, hacer un manejo eficiente de los recursos y llevar a cabo acciones adecuadas de gobernanza, aportando, gracias a sus labores misionales, a la creación de valor social. Con tal fin, se exponen algunas de las tendencias para la gestión en educación superior, y se plantean los principales desafíos financieros y de gobernanza a que se enfrenta en la actualidad. De manera particular, se presenta en este capítulo una mirada desde el enfoque de los escalones superiores y las finanzas corporativas comportamentales, perspectivas orientadas a comprender las características de los directivos, su influencia en la toma de decisiones y el impacto en los resultados organizacionales, haciendo énfasis en la financiación e inversión.
Macroeconomía en los tiempos del Covid-19: un análisis de equilibrio dinámico estocástico para Colombia
Authors: Botero Jesús , Arellano Matheo , Montañez Diego , González Auhing Marcos
Published: April 2024

El presente artículo, que aborda la construcción de un modelo dsge-sir que incorpore las complejas relaciones entre enfermedad, contención y dinámica económica, consta de cuatro secciones además de esta:2 en la segunda, se analizan los mecanismos a través de los cuales se conectan los fenómenos económicos y los fenómenos epidemiológicos; la tercera discute el tema de la calibración; la cuarta presenta los resultados del modelo; y la quinta se ocupa de las conclusiones y recomendaciones de políticas, que permitan atenuar el efecto tanto económico (medios de vida) como en pérdidas humanas (vida).
Efectos regionales del aislamiento por Covid-19 en Colombia
Authors: Bonet Morón Jaime , Ricciulli Marín Diana , Pérez Valbuena Gerson , Galvis Aponte Luis , Haddad Eduardo A. , Araújo Inácio F. , Perobelli Fernando S.
Published: April 2024

El texto está compuesto de cuatro secciones. La segunda presenta la metodología empleada en el cálculo de la pérdida económica nacional, regional y sectorial. El tercer apartado expone los resultados de los diferentes escenarios, en donde se parte del aislamiento preventivo de los mayores de 70 años y se incrementa gradualmente el confinamiento hasta llegar al 60 % de los empleados en aislamiento. En la última sección se concluye.
Covid-19 y consumo de los hogares: hechos estilizados a partir de datos del Grupo Éxito
Authors: Bonilla Mejía Leonardo , Carranza-Romero Juan Esteban , Fuentes Vélez Mariana , González Esquivel Felipe , Pérez Pulgarín Stiven , Villamizar-Villegas Mauricio
Published: April 2024

En este capítulo se presenta un estudio de la evolución del consumo de los hogares en Colombia utilizando datos de las ventas del Grupo Éxito, quien es actualmente el líder en la gran superficie del país, con cobertura nacional y una participación de mercado cercana al 29 % en este segmento (La República, 2020). Los datos de muy alta frecuencia permiten no solo hacer un seguimiento en tiempo real de la evolución de las ventas, sino además desagregar en detalle por segmento de consumo, región, estrato y medio de pago. Nuestro análisis se enfoca en los primeros siete meses del año 2020, durante los cuales se identifican dos tipos de eventos que han tenido un impacto importante sobre las ventas. El primero es el inicio de la pandemia y la puesta en marcha de las medidas de restricción de movilidad, que tuvo lugar en el mes de marzo. En segundo lugar, están los dos días sin iva promovidos por el gobierno nacional, que tuvieron lugar el 19 de junio y el 3 de julio. El capítulo se organiza en seis secciones. En la sección 2 se expone la evolución de las ventas totales de tres grandes segmentos de consumo: mercado, ropa y electrodomésticos y artículos del hogar. En la tercera y cuarta, se estudia la heterogeneidad regional y de ingreso, respectivamente. En la quinta, se sigue la evolución de los medios de pago; y en la sexta, se concluye.
Hechos y recomendaciones para enfrentar los efectos negativos del Covid-19 en la educación colombiana
Authors: Abadía Luz Karime , Bernal Gloria , Gómez Silvia , Alonso Santiago
Published: April 2024

Este capítulo presenta algunos hechos y recomendaciones de política pública educativa (a corto y largo plazo) para mejorar la calidad de los colegios oficiales del país (e incluso de algunos no oficiales), y su efectiva reacción ante momentos de crisis como el que se está viviendo hoy en día a causa de la pandemia. La disponibilidad y el buen uso de la tecnología se muestra como un insumo clave para este fin. Así mismo, se resalta la importancia de contar con un compromiso colectivo no solo del gobierno nacional y de los gobiernos locales, sino de los docentes, los estudiantes, los padres de familia, empresarios y, en general, de toda la sociedad colombiana.
Una mirada regional al impacto económico del Covid-19 desde el indicador mensual de actividad económica (IMAE) para el Valle del Cauca
Authors: Sierra Lya Paola , Vidal Pavel , Cerón Julieth
Published: April 2024

El capítulo tiene la siguiente estructura: en la sección 1 se explica la metodología y las variables utilizadas para la estimación del imae Valle y el análisis del impacto del Covid-19 en la economía del Valle; en la 2 se exponen los resultados; y, por último, se ofrecen las conclusiones.
Conceptos y componentes de la diversidad biológica marina: aporte desde las ciencias biológicas
Authors: Seco Pon Juan Pablo
Published: April 2024

El término diversidad biológica engloba aspectos relacionados con la variabilidad de los organismos vivos, incluidos los ecosistemas terrestres y marinos y otros ecosistemas acuáticos y los complejos ecológicos de los que forman parte; comprende, de esta manera, la diversidad dentro de cada especie y entre las especies, y la de los ecosistemas. Pero, ¿a qué nos referimos con los términos variabilidad, especies y ecosistemas? Se presenta un aporte desde las ciencias biológicas para una comprensión holística e integrada de estos conceptos, con énfasis en el ambiente marino
Bitácora, relatos de aprendizaje
Authors: García-Mera Laura Catalina
Published: April 2024

El presente capítulo narra parte del viaje de la Universidad del Rosario como institución educativa y, a su vez, narra parte de la experiencia de los estudiantes de primer semestre, quienes, en el recorrido de la asignatura Cátedra Rosarista, inician un camino de reflexión sobre su proceso de aprendizaje. Particularmente, se centrará en la oportunidad de enseñanza que significó la pandemia de 2020 para la institución, valiéndose de las narraciones de los estudiantes en su primer semestre como universitarios. Para ello, se retomarán los postulados de aprender a aprender, las reflexiones de los estudiantes y el aprendizaje para y a lo largo de la vida.
Espetáculos itinerantes: o papel dos artistas, do público e do espaço cênico em processos de criação na cidade
Authors: Bezerra Rodrigues Francisco Wagner
Published: April 2024

Este artigo propõe uma reflexão sobre espetáculos intinerantes. Teve como referência as peças Fosforos, nuvens e passarinhos (Teatro da Travessia), Mil mulheres e uma noite (As Meninas do Conto), Hoje o escuro vai atrasar para que possamos conversar (Grupo XIX de Teatro). A cidade vista como dramaturgia, pois ela própria oferece um “texto” que é fruto do que nela acontece.
Da rua à galeria: experiências de educação informal na construção da série “UóHol” de Rafael Bqueer
Authors: Freire Camila Ferreira Araujo
Published: April 2024

Este artigo apresenta a perspectiva da educação informal na construção pessoal e profissional de Rafael Bqueer. Para isto analisa a série “UóHol”, obra que visibiliza e celebra ícones pretas pertencentes ao imaginário cultural brasileiro, dialogando sobre culturas dissidentes e periféricas, bem como outros protagonismos para a comunidade LGBTQIA+.
Pesquisa em artes: temporalidades inconciliáveis
Authors: Carneiro Isabel
Published: April 2024

O sistema 1 por dia é uma forma fragmentária que tenta conter o todo em partes, asistematização do pensamento artístico em intervalos de um dia permite que esmiúcemos aomáximo cada parte fragmentada, que seria a única maneira de tentar abarcar sistematicamenteo pensamento que é, no todo, inapreensível ou inabarcável.
Notas sobre o Infrafino – volume 1 (depois de Duchamp)
Authors: Sá Alexandre
Published: April 2024

Embora o silêncio-infrafino seja superestimado, o seguinte texto de artista objetiva rever tal legado, procurando estabelecer vínculos para além da concretude da matéria. Nenhuma explicação possível. Nenhum resumo possível. Alegoria sobre a impossibilidade.
Perioperative cardiac risks in myasthenia gravis
Authors: Nag Deb Sanjay , Chatterjee Abhishek , Mahanty Pratap Rudra , Sam Merina , Bharadwaj Murari Kumar
Published: April 2024

Myasthenia gravis (MG) is an autoimmune disorder that affects the neuromuscular junction. The primary pathology in MG involves the presence of autoantibodies to acetylcholine receptors (AChRs), which results in qualitative and quantitative reductions in the availability of functional AChRs. Cardiac muscles are also affected, resulting in various perioperative cardiac complications. Antistriational antibodies are commonly reported in MG cases with cardiac involvement. In the presence of thymoma, the prevalence of cardiac manifestations in patients with MG increases to approximately 10%-15%. Cardiac involvement in MG may range from asymptomatic electrocardiogram changes to ventricular tachycardia, myocarditis, conduction disorders, heart failure, and sudden death. Increased incidence of atrial fibrillation, ventricular and supraventricular extra systoles, and prolonged QTc have also been reported in patients with MG. Clinicians should consider the evaluation of autonomic dysfunction and risk of cardiovascular disease in patients with MG .
Management of geriatric acetabular fractures: Contemporary treatment strategies
Authors: Tosounidis Theodoros , Chalidis Byron
Published: April 2024

Acetabular fractures in the geriatric population are typically low-energy fractures resulting from a fall from standing height. Compromised bone quality in the elderly, as well as this population’s concomitant medical comorbidities, render the management of such fractures challenging and controversial. Non-operative management remains the mainstay of treatment, although such a choice is associated with numerous and serious complications related to both the hip joint as well as the general condition of the patient. On the other hand, operatively treating acetabular fractures (e.g. , with osteosynthesis or total hip arthroplasty) is gaining popularity. Osteosynthesis can be performed with open reduction and internal fixation or with minimally invasive techniques. Total hip arthroplasty could be performed either in the acute phase combined with osteosynthesis or as a delayed procedure after a period of non-operative management or after failed osteosynthesis of the acetabulum. Regardless of the implemented treatment, orthogeriatric co-management is considered extremely crucial, and it is currently one of the pillars of a successful outcome after an acetabular fracture.
Pioneering role of machine learning in unveiling intensive care unit-acquired weakness
Authors: Dragonieri Silvano
Published: April 2024

In the research published in the World Journal of Clinical Cases , Wang and Long conducted a quantitative analysis to delineate the risk factors for intensive care unit-acquired weakness (ICU-AW) utilizing advanced machine learning methodologies. The study employed a multilayer perceptron neural network to accurately predict the incidence of ICU-AW, focusing on critical variables such as ICU stay duration and mechanical ventilation. This research marks a significant advancement in applying machine learning to clinical diagnostics, offering a new paradigm for predictive medicine in critical care. It underscores the importance of integrating artificial intelligence technologies in clinical practice to enhance patient management strategies and calls for interdisciplinary collaboration to drive innovation in healthcare.
Detection and analysis of serum bile acid profile in patients with colonic polyps
Authors: Ji Xin , Chen Hong
Published: April 2024

BACKGROUND

Analyzing the variations in serum bile acid (BA) profile can provide a certain biological basis for early warning and prevention of various diseases. There is currently no comprehensive study on the relationship between the serum BA profile and colonic polyps.

AIM

To study the serum BA profile detection results of patients with colonic polyps, and analyze the correlation between BA and colonic polyps.

METHODS

From January 1, 2022, to June 1, 2023, 204 patients with colonic polyps who were diagnosed and treated at Zhongda Hospital Southeast University were chosen as the study subjects, and 135 non-polyp people who underwent physical examination were chosen as the control group. Gathering all patients' clinical information, typical biochemical indicators, and BA profile.

RESULTS

Compared with the control group, the serum levels of taurocholic acid, glycocholic acid, glycochenodeoxycholic acid, and taurochenodeoxycholic acid in the colonic polyp group were significantly higher than those in the control group, while the content of deoxycholic acid (DCA) was lower than that in the control group (P < 0.05). When colonic polyps were analyzed as subgroups, it was shown that there was a strong correlation between changes in the BA profile and polyp diameter, location, morphology, pathological kind, etc.

CONCLUSION

The serum BA profile showed significant changes in patients with colonic polyps, with a significant increase in primary conjugated BA content and a decrease in secondary free bile acid DCA content. There is a certain correlation between primary free BA and pathological parameters of polyps.
Relationship between clinical belonging, professional identity, and nursing information ability among nursing interns: Model construction
Authors: Zhang Gai , Huang Shao-Juan , Li Shu-Fang
Published: April 2024

BACKGROUND

Clinical belonging refers to the feeling that clinical medical staff feel recognized and accepted by others or groups. The level of clinical belonging of nursing interns affects students’ learning motivation and confidence, which in turn affects their clinical practice behavior.

AIM

To explore the effects of professional identity and nursing information ability on clinical belonging among nursing interns and establish a relationship model for these factors.

METHODS

The researchers used the convenience sampling method to select 682 nursing interns from China. The survey was conducted using a general information questionnaire, clinical sense of belonging scale, nursing information ability self-assessment scale, and a nursing student professional identity questionnaire. The mediating effect of nursing information ability between their professional identity and clinical sense of belonging was analyzed using SPSS 21.0 and the path analysis in structural equation modeling.

RESULTS

The total scores of clinical belonging, professional identity, and nursing information ability of nursing interns were (104.29 ± 13.11) points, (57.89 ± 7.16) points, and (70.29 ± 6.20) points, respectively. Nursing information ability had a direct effect on the clinical sense of belonging (effect value = 0.46, P < 0.05). Occupational identity had a direct effect (effect value = 0.52, P < 0.05) and an indirect effect (effect value = 0.21, P < 0.05) on clinical belonging.

CONCLUSION

Nursing administrators in nursing colleges and hospitals should take effective measures to improve the professional identity and nursing information ability of nursing interns, as well as the clinical sense of belonging among nursing interns.