bluuebunny/crossref_metadata_2025 huggingface dataset:
Analisis Kelayakan Usaha (Studi Kasus pada UMKM Keripik "Selasih" Kab. Asahan, Sumatera Utara)
Authors: Lubis Utami Sasmita , Hamidah Siti , Rini Wulandari Dwi Etika
Published: September 2024

Penelitian ini bertujuan untuk (1) Menganalisis kelayakan aspek finansial dari UMKM Keripik “Selasih” (2) Mendeskripsikan keadaan aspek non finansial pada UMKM Keripik “Selasih”. Metode pendekatan yang digunakan pada penelitian ini berupa metode kuantitatif. Metode pengambilan responden pada penelitian ini menggunakan metode purposive sampling. Responden yang digunakan sebanyak 5 orang yang berasal dari pengurus UMKM Keripik “Selasih”. Teknik pengumpulan data dilakukan melalui observasi, dokumentasi, wawancara serta studi pustaka dengan data yang digunakan berupa data sekunder dan data primer. Aspek pasar dan pemasaran, aspek teknis dan teknologi, aspek sumber daya manusia serta aspek lingkungan dijelaskan berdasarkan analisis deskriptif. Untuk menganalisis kelayakan usaha pada UMKM Keripik “Selasih” digunakan analisis berupa BEP (Break Event Point), ROI (Return On Investment), serta B/C. Hasil dari penelitian ini diperoleh (1) Aspek finansial UMKM Keripik “Selasih” layak untuk dijalankan dengan jumlah rata-rata produksi pada empat produk lebih besar daripada BEP unit, rata-rata ROI sebesar 66,5%, dan rata-rata BC Ratio sebesar 0,66 (2) Aspek non finansial UMKM Keripik “Selasih” dalam kategori sangat baik dengan persentase sebesar 92,8%
Analisis Faktor Pengaruh Produksi Terhadap Produksi Daun Teh, Trend dan Diagram Sebab-Akibat di PT Perkebunan Nusantara IX Kebun Semugih Pemalang Jawa Tengah
Authors: Subagya Yola Rahma , Santosa Agus , YP Ni Made Suyastiri
Published: September 2024

Tujuan dari penelitian  untuk (1) Menganalisis pengaruh luas areal panen, tenaga kerja, curah hujan dan penggunaan pupuk bayfolan terhadap  produksi daun teh di PTPN IX, Kebun Semugih, Pemalang, Jawa Tengah. (2) Mengetahui  Trend produksi daun teh di PTPN IX untuk 6 Bulan yang akan datang (3) Mengetahui faktor-faktor yang menyebabkan kurang maksimalnya produksi daun teh di PTPN IX. Metode dasar yang akan digunakan dalam penelitian ini  mengggunakan metode deskriptif. Metode pelaksanaan menggunakan metode survei. Metode pengambilan responden menggunakan metode Sampling purposive,dalam penelitian ini jumlah responden yang diambil adalah 3 orang. Teknik pengumpulan data adalah wawancara, dokumentasi, observasi, dan pencatatan. Teknik analisis yang digunakan adalah analisis fungsi produksi Cobb Douglas, metode Trend dan analisis Fishbone. Pengujian hipotesis dilakukan dengan koefisien determinasi, uji F dan uji t. Hasil penelitian menujukan bahwa (1) Faktor-faktor produksi yang terdiri dari luas areal panen, tenaga kerja, pupuk bayfolan, dan curah hujan berpengaruh terhadap produksi daun teh di PTPN IX. (2)Trend produksi daun teh di PTPN IX, selama enam Bulan yaitu Bulan Juli 2022 sampai dengan Bulan Desember 2022 mengalami kenaikan. (3)Faktor-faktor yang menyebabkan kurang maksimalnya produksi daun teh di PTPN IX adalah faktor lingkungan, metode kerja dan tenaga kerja. Kata kunci : Faktor Produksi, Produksi Daun Teh, Trend Produksi Daun Teh.
Analisis Pengaruh Segmenting Targeting Positioning Terhadap Minat Beli Ulang Konsumen Produk Teh Tambi Di Wonosobo Jawa Tengah
Authors: Iswara Nabila Cintya , Budiarto Budiarto , Suprihanti Antik
Published: September 2024

Increasing competition between companies requires companies to improve their marketing strategies. One way is to know in advance the characteristics of consumers so that companies can find out the factors that influence consumers in repurchasing a product. In this case the company can use segmenting, targeting, positioning strategies. Therefore, this study aims to identify the segmenting, targeting, and positioning of Tambi Cap Petruk black tea products and analyze the effect of segmenting, targeting and positioning on the repurchase interest of PT Perkebunan Tambi black tea products. The method used is descriptive research method with the implementation method, namely the survey method. The results of the analysis show that: (1) Tambi Cap Petruk's black tea product segmentation is consumers aged 17-60 years and the majority of consumers are women. Cap Petruk's targeting black tea products are consumers who prioritize quality and affordable prices. Positioning or consumer perceptions of Tambi Cap Petruk black tea products are products with affordable prices, easily recognizable logos or packaging and product quality. (2) Segmenting targeting positioning affects buying interest in Tambi Cap Petruk black tea products.Keywords: Segmenting; Targeting; Positioning; Consumer’s Repurchase Interest; Tambi Cap Petruk Black Tea
Faktor-Faktor yang Memengaruhi Kepuasan Konsumen di Susu Sarjana Cabang UNY Yogyakarta
Authors: Nazifa Naura , Permai Ni Made Suyastiri Yani
Published: September 2024

Penelitian ini bertujuan untuk 1) mengetahui karakteristik konsumen Susu Sarjana Cabang UNY Yogyakarta 2) menganalisis tingkat kepuasan konsumen Susu Sarjana Cabang UNY Yogyakarta 3) menganalisis faktor-faktor yang memengaruhi kepuasan konsumen di Susu Sarjana Cabang UNY Yogyakarta. Metode dalam penelitian ini menggunakan pendekatan kuantitatif dengan jenis penelitian survei. Metode penentuan lokasi dilakukan secara purposive. Metode pengambilan sampel yang digunakan adalah nonprobability sampling dengan purposive sampling. Jumlah sampel yang digunakan sebanyak 50 responden. Jenis data yang digunakan meliputi data primer dan data sekunder. Metode pengambilan data menggunakan wawancara, kuesioner, observasi, dan dokumentasi. Penelitian ini menggunakan teknik analisis deskriptif dan regresi linier berganda. Hasil penelitian menunjukkan bahwa 1) karakteristik konsumen Susu Sarjana Cabang UNY didominasi oleh perempuan, berusia 18-25 tahun, memiliki pendidikan terakhir sekolah menengah atas (SMA), dan merupakan pelajar atau mahasiswa yang pernah membeli sebanyak lebih dari dua kali 2) kepuasan konsumen Susu Sarjana Cabang UNY Yogyakarta berada pada tingkat sangat puas berdasarkan penilaian konsumen sebesar 87,76% 3) atribut produk dan kualitas pelayanan berpengaruh terhadap kepuasan konsumen Susu Sarjana Cabang UNY Yogyakarta.
Adolescent Systemic Hypertension: Late Diagnosis of Coarctation of the Aorta
Authors: Barrios Carlos , Giuffre Michael
Published: September 2024

Coarctation of the aorta accounts for 5–7% of all the cases of congenital heart disease, with an estimated incidence of approximately 3 cases per 10,000 births. Coarctation of the aorta typically presents in the neonatal or early childhood period. The less severe coarctation patients may have subtle clinical findings such as elevated upper limb blood pressure, diminished femoral pulses, and a systolic ejection murmur that often transmits to the back. This case demonstrates that coarctation can be seen in the otherwise healthy adolescent population.
Ovarian Torsion
Authors: Gillis Emma
Published: September 2024

This article is aimed at describing what ovarian torsion is, the role that ultrasound has in torsion cases, as well as the sonographic features of ovarian torsion. Ovarian torsion is an infrequent but important cause of acute lower abdominal pain in women and is typically an indication for a pelvic ultrasound. Ultrasound is a fundamental diagnostic tool, which aids in the identification of ovarian torsion in women of all ages.
Dioctophyme Renale in the Canine Patient
Authors: Bogie Lisa Jones
Published: September 2024

Some northern Ontario communities do not have access to veterinarians. As a result, many dogs in this area are not spayed or neutered. This deficit leads to over breeding and an increased number of strays. This results in harsh living conditions where dogs are forced to scavenge for food leading to an increased risk of contracting a parasitic infection. Dioctophyme renale, commonly referred to as “giant kidney worm” is a parasitic roundworm found in mammals. Animal rescue groups traveling to Northern Ontario communities are bringing back stray dogs for veterinary care and for adoption. The case study presented describes this rare parasitic infection. The prognosis if left untreated is fatal. Ultrasound is a useful diagnostic modality for diagnosing giant kidney worms as it has no adverse effects.
The Role of Contrast Enhanced Ultrasound (CEUS) in Assessing a Rare Undifferentiated Embryonal Sarcoma of the Liver
Authors: Cartwright Brianna
Published: September 2024

Focal liver lesions are common findings in diagnostic imaging, but not all liver lesions are common. Complex, unique hepatic tumours can be challenging to differentiate and diagnose regardless of imaging modality. An example of this is demonstrated in a case of a 23-year-old female with a large liver mass comprised of cystic, solid, and hemorrhagic components. The lesion lacked classic features on imaging, so a Contrast Enhanced Ultrasound (CEUS) was performed to further interrogate the solid aspects of the mass. The study provided reliable findings indicative of a primary hepatic malignancy, supporting previously performed radiology examinations, laboratory results, and ultimately the patient's diagnosis of an undifferentiated embryonal sarcoma of the liver. Results from the CEUS exam assisted to accelerate proper management for the patient without the need for an invasive tissue biopsy, additional radiation exposure, or increased risk of nephropathy. This case study further outlines the benefits and value of CEUS in the evaluation of the patient's hepatic lesion, and its use in the continued assessment of focal liver lesions.
Evidence-Based Approaches to Enhance Teaching and Learning in Sonography
Authors: Germain Jane St
Published: September 2024

A postgraduate sonography program has adult students. To incorporate appropriate teaching and learning methods, educators should consider adult learning theories as well as different educational methods to design and develop the curriculum to engage the adult learners and have them ready for their clinical practicum. This literature review describes the adult learning theories, and introduces two methods of teaching; simulation-based learning and flipped classroom; to enhance learning and teaching.
Rationale for an Integrative/Interactive Approach to the Diagnostic Ultrasound for Transitioning Patients with Juvenile Idiopathic Arthritis
Authors: Dima Robert , Appea Priya , Semalulu Theresa
Published: September 2024

Juvenile idiopathic arthritis (JIA) is a group of debilitating childhood rheumatic diseases. More than 50% of patients have persistent disease into adulthood. As a result, smooth transition from paediatric to adult care is essential for these patients, especially as disruption in care has been linked to poor outcomes. In the following manuscript, we provide a review of the literature on JIA transition, and a commentary on Diagnostic Medical Sonographer (DMS) role development and the use of ultrasound as an educational tool. In the context of the literature surrounding these topics, we present an argument for a potential new role of the DMS in the education and empowerment of children suffering from JIA transitioning to the adult care model. Barriers to, and advantages of this new role are discussed briefly, and an example framework of implementation is proposed.
Making a Difference: Blue Nevus versus Melanoma
Authors: Yuen Ray T.
Published: September 2024

The blue nevus is an uncommon lesion that may appear worrisome due to its similar appearance to the sinister melanosarcoma. The blue nevus is a subset of dendritic melanocytic proliferations that is commonly believed to be remnant embryonal neural crest cells that failed to migrate from the dermis.

This is a case of a 58-year-old male who presented with a bluish lump on his right third finger for 6 months complaining of dull ache, swelling and decreased range of motion (ROM). The impression of the lesion was of a blue nevus, a benign tumour that required investigation and follow up due to concern for a melanoma. His pain and decreased ROM can be attributed to repeated use due to his trade and were later deemed as a red herring presentation.

Although histopathology continues to be the gold standard in the diagnosis and classification of melanocytic nevi lesions, ultrasound imaging can be considered as a quick tool to characterise and quantify such lesions as a preliminary exam to rule out more concerning features of melanomas.
Infection Control and Safety Protocols to Protect Sonographers and Patients During the COVID-19 Pandemic
Authors: Park Grace , Bahador Salwa , La Linda
Published: September 2024

The coronavirus disease (COVID-19) pandemic has had an extensive health, social, and economic impact around the world. Owing to its high rate of transmission, implementing infection control and safety protocols become crucial in protecting sonographers and patients. This literature review explored various databases and search engines to acquire published peer-reviewed articles and multiple resources related to Canadian COVID-19 statistics and evidence-based practices. Information was used to discuss the importance of infection control and recommendations in adopting proper personal protective equipment (PPE) protocols. This includes wearing appropriate PPE, correct donning and doffing procedures prior to and after interactions with patients, and proper hand hygiene. To effectively fight COVID-19, it is essential for both sonographers and patients to adhere to these recommendations and protocols.
Dandy–Walker Malformation
Authors: Nashnoush Mohamed
Published: September 2024

Dandy–Walker Malformation (DWM) is a condition affecting the cerebellum. It consists of hypoplastic vermis, cystic enlargement of the fourth ventricle, and cystic formation near the posterior fossa. Ultrasound and magnetic resonance imaging scan are beneficial in inspecting these complications for both fetal and infantile cases. In this case series, fetal manifestations of DWM are explored through discussing maternal vitals, gestational age, clinical findings, and diagnostic imaging features (e.g., areas of encephalic enlargement and presentations of cystic dilation). It was observed that this condition is often mistaken for an arachnoid cyst, Blake’s pouch cyst, Joubert anomaly, or Arnold–Chiari malformation. It is, therefore, essential to develop a framework with sufficiently conspicuous DWM imaging features and clinical manifestations to improve diagnostic accuracy.
A Rare Case of a Live Dichorionic Diamniotic Twin Tubal Ectopic Pregnancy
Authors: Lu Jia Qian
Published: September 2024

The incidence of live, twin tubal ectopic pregnancies is extremely rare, occurring in 1 in 125,000 pregnancies. This case report describes the clinical manifestation, clinical history, and ultrasound findings of a 39-year-old female with no known significant risk factors for an ectopic pregnancy but was diagnosed by ultrasound imaging with a live, twin, tubal ectopic at a gestational age of 5 weeks, 5 days. This case report also documents the patients’ management and treatment provided.
Gamification of an Interdisciplinary Point-Of-Care Ultrasound Symposium and Its Perceived Impact on Learning
Authors: Zhang Jimmy , Unni Rudy R. , Curly Emily , Dadgar Kayla , Woo Park Sang , Maniate Jerry , Halman Samantha , Prager Ross
Published: September 2024

Background

Point-of-care ultrasound (POCUS) is a valuable diagnostic tool for physicians across medical specialties. New methods to increase trainee exposure and comfort with POCUS are important to help integrate POCUS into post-graduate medical education. We assessed whether gamification of POCUS teaching through an interdisciplinary 1-day POCUS competition and symposium would increase learner comfort with core scans and whether participants perceived that the gamification and interdisciplinary nature of the event enhanced their educational experience.

Methods

Sonowars 2020 was a 1-day interdisciplinary POCUS competition open to all trainee physicians at two local teaching hospitals. Trainees participated in a mix of didactic and competitive sessions, where participants were adjudicated on their image acquisition, interpretation, visuospatial comprehension, and clinical judgement. Pre and post-event surveys using a 5-point Likert scale were developed to assess three domains: comfort with common scans, perceived impact of interdisciplinary structure on learning, and perceived impact of gamification on learning. In addition, ordinal regression was used to assess for an increase in comfort with common scans pre- and post-event.

Results

A total of 44 trainee physicians participated in the event. The response rate for the preand post-surveys was 39/44 (89%) and 38/44 (86%), respectively. The median (range) post-graduate year of training was 1 (1–7). Ordinal regression showed an increase in comfort post-event for nearly all scans. Respondents indicated that the competition format enhanced learning, considering it more engaging than either lecture or small group format. One year post-event survey indicated that the majority of participants pursued further ultrasound training incited by Sonowars.

Discussion

Sonowars 2020 demonstrated that an interdisciplinary ultrasound symposium with lowstakes competition was associated with increased perceived comfort with POCUS amongst trainees and that its gamification and interdisciplinary format were perceived to enhance the educational experience. Furthermore, implementing POCUS into post-graduate medical training requires trainee engagement for uptake and integration into daily patient encounters. Therefore, exposing trainees to POCUS in a novel format like Sonowars 2020 may provide a foundation for further POCUS skill acquisition among trainees.
Hydrops Fetalis
Authors: Lonsdale Angela
Published: September 2024

Hydrops fetalis is a complex and fascinating disorder. This article explains the characteristics of each type of hydrops fetalis, immune and non-immune. The etiology and the associated underlying conditions leading to the development of these disorders are also discussed. The ultrasonographic appearance of a classic case of hydrops fetalis is described including variations in its appearance and its numerous differential diagnoses. Several causes of non-immune hydrops fetalis are outlined and briefly discussed. The article concludes with delivery recommendations and discusses a future plan of action for the diagnosis of hydrops fetalis.
Sonographic Differentiation of the Cystic Masses in the Popliteal Fossa
Authors: Li Tony Y.
Published: September 2024

Cystic masses are very common in the popliteal fossa. Because of their diverse entities and anatomical closeness, it is challenging to differentiate one lesion from another during ultrasound investigation. To facilitate an understanding of these cystic masses and to apply this knowledge towards a clinical lesion determination, the most commonly seen cystic masses such as Baker cysts, semimembranosus bursitis, meniscal cysts of the posterior horn of the medial meniscus, posterior cruciate ligament (PCL) cysts and the misleading tortuous vein in the popliteal fossa are discussed here in detail based on their sonographic characteristics.
Malignant Angiomyolipoma and Tuberous Sclerosis: A Case Report
Authors: Hesson Noor Mihyar
Published: September 2024

A 32-year-old male patient presented at the emergency room with a palpable left upper quadrant mass. Ultrasound and computed tomography examinations revealed a left upper quadrant mass displacing the left kidney and spleen, but were not able to rule out malignancy. The patient’s other clinical signs and symptoms were deemed suspicious for tuberous sclerosis complex (TSC). After several other tests and a referral to a dermatologist, the suspicion was confirmed. A biopsy identified the lesion as a malignant angiomyolipoma (AML) associated with TSC. The patient has been referred to a cancer centre for treatment and will be seen regularly for radiation therapy sessions.

AML is typically a benign renal lesion that is easily diagnosed with computed tomography or sonography. However, AML may occasionally mimic malignant lesions in its appearance, or can become malignant itself. Patients with TSC are more likely to develop malignant renal lesions than the general population. There are multiple treatment options for AML, and the course of action is dependent on the size of the lesion and the patient’s symptoms. This case perfectly illustrates the importance of using diagnostic imaging modalities in a complementary manner to correctly diagnose patients and provide optimal care and treatment.
Advantages of Transrectal Ultrasound for Staging Rectal Cancer Compared to MRI and CT
Authors: Sutharzanan Sharmatha
Published: September 2024

This article discusses the advantages of using ultrasound in detecting the degree of invasion of rectal carcinoma, compared with other imaging modalities such as computed tomography (CT) and magnetic resonance imaging (MRI). Examples of cases are provided to see how ultrasound differentiates T1, T2, T3, and T4 rectal tumours. In the past, ultrasound was used mainly for detecting metastasis in the liver and other organs. For rectal examination a transrectal probe is used to identify and stage the lesions. Transrectal ultrasound, also known as TRUS, detects lesions located less than 14 cm from the anus and may not be used for the upper rectum. Aside from detecting adjacent lymph nodes, the sensitivity of transrectal ultrasonography for detection and local staging of rectal tumours (within 14 cm of the anus) is 90–100% (versus 50–80% for CT), and its specificity is 75% (versus 33–80% for CT). TRUS has been shown to be the most accurate method for the determination of the depth of wall penetration (from 62 to 92%) and is comparably accurate for lymph node metastases (from 64 to 88%). Overall, transrectal ultrasound is able to detect malignant infiltration of perirectal fat and perirectal node involvement suggesting that this technique is a cost-effective, reliable adjunct for staging rectal cancers.
The Role of Echocardiography in Pediatric Heart Transplantation
Authors: Greenway Steven C.
Published: September 2024

Although invasive investigations such as endomyocardial biopsy and coronary angiography remain the gold standard for the diagnosis of rejection or cardiac allograft vasculopathy echocardiography has an important role in heart transplantation. Echocardiography's ease of use and non-invasive nature make it an essential part of clinical care, particularly for children, both before and after transplantation. However, many echocardiographic parameters are abnormal post-transplant and this limits the sensitivity and specificity of echocardiography for the detection of rejection. To increase the utility of echocardiography for post-transplant monitoring measures must be standardized. Evaluation of serial data from an individual patient, rather than comparing results to population-derived normal values, may further increase reliability and sensitivity. This review describes the uses and limitations of echocardiography in pediatric heart transplantation.
Rare Sonographic Presentation of De Quervain's Disease
Authors: Li Tony Y
Published: September 2024

The coexistence of focal enlargements of the tendons both proximal and distal to the extensor retinaculum in the first compartment of de Quervain's disease is rare. The first case of an ultrasound study on such a pathologic change is documented here. A possible reason for this unique presentation may be due to the repetitive sliding of the tendons through the constricted region caused by a thickening of the retinaculum. This results in an inflammatory reaction followed by subsequent swelling of the tendons both proximal and distal to the constricted region.
Simulators in Ultrasound Education
Authors: Thomas Laura
Published: September 2024

Over the past decade ultrasound simulators have become more commonplace. MetaPhor ScanTrainer is the simulator that has been purchased by Mohawk/McMaster. The Scan Trainer uses haptic devices (in the form of transducers) to simulate real-time scanning. While moving the transducer, the student is scanning an actual volume of anatomy that is being demonstrated within a virtual patient. This technology allows the student to scan obstetrics, transvaginal, breast, and scrotum before opportunity clinical placement, as well as the ability to scan pathological cases. Third-year ultrasound students were surveyed in the spring of 2017 with an overall positive experience expressed. Future developments with the scan trainer will incorporate case generation and continuing education along with further integration into our curriculum.
Sonography of the Outflow Tracts of the Fetal Heart: Abnormalities
Authors: Suchet Dr. Ian
Published: September 2024

A thorough knowledge of the normal appearance and common variants of the outflow tracts in combination with systematic evaluation of the standard views can diagnose or exclude abnormalities.

Cardiovascular malformations account for a significant percentage of infant deaths and half of all deaths from malformations. Despite these numbers, cardiac anomalies are the most commonly overlooked defects on an antenatal ultrasound.

Antenatal recognition of infants who will have a ductus-dependent circulation after birth enables safe postnatal management, preventing neonatal collapse and possible cerebral injury before cardiopulmonary bypass.

This paper describes a systematic approach to anomalies of the outflow tracts based on the size, location, orientation, number, and flow characteristics of the major mediastinal vessels on the standard views described in Part 1.

Antenatal detection of a fetus who will have a ductus-dependent circulation after birth or who has simple transposition of the great arteries with a restrictive foramen ovale may be life saving and has been shown to confer benefit with improved neonatal outcome.
Extracorporeal life support for severe leptospirosis: Case series and narrative review
Authors: Milovanovic Lazar , Singh Gurmeet , Townsend Derek , Nagendran Jayan , Sligl Wendy
Published: September 2024

Introduction:

Leptospirosis can be associated with multi-system organ failure (MSOF) and significant morbidity and mortality. Extracorporeal life support (ECLS) has been used as salvage therapy for severe leptospirosis complicated by acute respiratory distress syndrome (ARDS). Current knowledge in this field is limited, with no standardized treatment approaches. We aim to describe the literature to date on the use of ECLS in patients with leptospirosis, highlighting associations, outcomes, and complications.

Methods:

We report on the successful use of ECLS in two cases of severe leptospirosis and conduct a narrative review of the literature. Using a search strategy developed in consultation with a medical librarian and validated across pre-selected articles, several databases were searched. We included case reports, case series, cohort studies, and prospective studies of adult patients with confirmed leptospirosis undergoing ECLS. Editorials, surveys, or opinion articles without primary patient data were excluded. Overall mortality was our primary outcome.

Results:

Two cases of previously healthy males presenting with ARDS due to leptospiral infection are described. Literature review identified 25 articles containing 43 reported cases of patients treated with ECLS for severe leptospirosis. Patients were mostly young and male. Overall mortality was 16%. The most common complication recognized was acute renal failure requiring renal replacement therapy. Additional complications included diffuse intravascular coagulation, necrotizing pancreatitis, and limb ischemia.

Conclusion:

Leptospirosis should be considered in patients with epidemiologic exposure(s) presenting with critical illness, including ARDS and MSOF. ECLS is a viable rescue strategy in severe leptospirosis, even with established MSOF.
Clinical practice guideline supported administration of monoclonal antibody therapy for high-risk patients with COVID-19: Experience of a quaternary care centre
Authors: Hammond Keely , Bourdeau François , Klein Marina , Vinh Donald C. , Semret Makeda
Published: September 2024

Background:

Immunocompromised patients remain at risk of progression to severe COVID-19 disease.

Methods:

We describe clinical COVID-19-related outcomes after administration of anti-SARS-CoV-2 monoclonal antibodies (mAb) following institutional clinical practice guidelines (CPGs) in 205 high-risk patients between November 2021 and April 2022 at a Canadian quaternary care centre.

Results:

Median patient age was 59 years; 102 (50%) were female. Eighty-two (40%) were transplant recipients, 47 (23%) patients had hematologic malignancies, 25 (12%) had solid organ malignancies, and 51 (25%) had another indication. Forty-eight (23%) had received fewer than two doses of anti-SARS-CoV-2 vaccines. The majority (80%) had mild disease at presentation with 14% moderate and 6% severe. Median time from symptom onset to mAb administration was 3 days (IQR 2.0-5.5 days). Of those who received mAb as outpatients, 90 (93%) had favourable clinical outcomes (no COVID-19-related hospitalizations or death within 3 months). Of those who received mAb as inpatients, 93 (86%) had favourable outcomes (discharged without COVID-19-related re-admission or death), 4% were re-admitted, and 10% died. In logistic regression analysis, only disease severity at time of mAb administration was associated with unfavourable outcomes. Fewer than two vaccine doses was not associated with unfavourable outcomes, suggesting potential benefit among the under-vaccinated. There was a significant difference in adherence to CPGs between administration of mAb in outpatients versus inpatients (adherent for 85% versus 58%, p<0.001), where non-adherence occurred in cases of severe disease.

Conclusion:

CPG-supported mAb administration for management of COVID-19 in high-risk patients was associated with favourable clinical outcomes and may be a useful model to guide future therapies.
“Microbiology can be . . . ” Student Competition to Develop Resources about Infectious Diseases that Improve Health Literacy
Authors: Marenzoni Maria Luisa , Ciappelloni Raoul
Published: September 2024

The European Association of Establishments for Veterinary Education emphasizes the importance of communication skills and teamwork for student success in clinical practice. Traditionally, many veterinary curricula lacked standardized formal training in acquiring these essential skills. Effective communication and collaborative teamwork are not only crucial for fulfilling the clinical responsibilities of the veterinary profession but also play a pivotal role in the broader societal context. Veterinarians, in their social role, serve as scientific communicators for the community. This role involves conveying scientific concepts, even complex ones, with a particular emphasis on their significance for public health, reaching a diverse audience. Currently, there is a growing public health necessity to improve health literacy, which refers to the ability to access, understand, appraise, and use information to support healthy choices by society, especially for topics like infectious diseases and vaccination. This became more evident during the global COVID-19 pandemic. This teaching tip describes the development, organization, and broad outcomes of a student competition introduced during a standard veterinary medicine course to design novel resources on microbiology and infectious disease-enhancing health literacy. Three separate events were organized during the academic years 2020–2023. The third-year veterinary medicine students attending the 3-month course on infectious diseases of small animals participated in a student competition aimed at promoting creativity and innovation. Their task was to develop novel resources that delivered informative content to the public concerning microbiology and infectious diseases. Participation was voluntary and students participated in groups of 5–6. Overall, 125 students created 22 projects on microbiology and infectious diseases that were able to enhance health literacy. This approach allowed students to engage with the content and convey foundational knowledge to others in an easily accessible way. This skill of communicating with the public using easy-to-understand language is essential for success in the veterinary medicine profession. The resources produced, such as drawings, comics, games, and videos, constitute informative sources. Thus, they were published online on a scientific journal to disseminate knowledge of infectious diseases to a broader audience.
Science and Philosophy in the Indian Buddhist Classics, Vol 2: The Mind
Authors: Osman Bakar
Published: September 2024

My review of Volume 1 of the four-volume Science and Philosophy in the Indian Buddhist Classics appeared in Al-Shajarah, vol. 26, no. 1 (June 2021) issue. In that review, I promised readers that once I get hold of the second volume, I will try to write a review of it. However, by the time I received a copy of the book – as a complimentary copy from a Malaysian disciple of His Holiness the Dalai Lama – it was too late for me to prepare a review of it to be in time for publication in the December 2021 issue of this Journal. Nonetheless, I am glad that my review of the anticipated volume is now before readers in the present issue of this Journal. In welcoming the first volume, I emphasise the significance that it has for cross-civilisational studies of religion and science. I view the second volume as another significant contribution to the growing literature on such studies. It will help meet the growing contemporary world need for a truly inclusive global narrative of the history of ideas to replace the Western-centric global narrative that has for too long reigned the academic and scholarly world.
Restoration of wear-out equipment using complex method of 3-D scanning and printing
Authors: Rassokhin D.O. , Nosovska O.V. , Kokodey D.V.
Published: September 2024

Introduction. Equipment restoration is a complex process that requires a comprehensive approach. Wear of parts and components of large-scale equipment leads to a halt in technological processes, reduced productivity, and sometimes to the complete breakdown of the entire production chain. Problem Statement. In most cases, on-site repair is impossible. However, modern CAD technologies not only allow assessing the extent of wear but also suggest a path to restoration. The widespread use of 3D printing has significantly simplified the process of creating individual parts. However, the high accuracy of the finished product largely depends on the quality of the model. Rapid acquisition of a highly accurate model is possible with the help of a 3D scanner. However, the extensive selection of 3D equipment, as well as materials requiring special conditions, significantly complicates predicting the quality of the finished product. Purpose. To examine the stages of repairing parts using 3D scanning and 3D printing. To provide accuracy values for the obtained models and the quality of finished parts using the example of a part made of semi-crystalline material PEEK. Materials and Methods. The economic feasibility of 3D printing worn parts is argued. Direct and indirect methods of restoration are considered. Accuracy values obtained when printing materials such as PAI2, PP, TPU, ABS, PEEK are provided. Results. The conditions for 3D printing polyetherketone PEEK are identified, as well as the optimal characteristics for obtaining a material with the highest wear resistance. Conclusions. The application of a comprehensive method for restoring worn parts using 3D printing and scanning is a promising and reasonable solution. However, despite the high accuracy and quality of the modern method, the analysis conducted shows the need to study the issues of fastening parts of worn elements and the adhesion of the materials used
Investigation of the stability of the neu-ronetwork in the surface identification system
Authors: Shapiro H.
Published: September 2024

The peculiarity of the current moment for modern shipping is that information technologies are intensively used in the fleet and port infrastructure. However, despite the introduction of new technical means of navigation, the problem of taking into account the influence of the human factor remains unsolved. The most promising direction of application of information technologies to solve the above-mentioned problem is the concept of e-Navigation, which is currently a key initiative of the IMO. The concept involves the use of "end-to-end" digital technologies of artificial intelligence and augmented reality in the part of intellectualization of the shipmaster's interface. These technologies are the key to a fundamentally new level of human-operator (master) interaction with navigation data in the digital environment, including for identifying the situation and recognizing situations. According to the results of the conducted research, the conclusion was obtained that the accuracy of the forecast of the ship's motion parameters by a neurocomputer is higher than when using a distributed computing system for this purpose. Thus, in the considered model situations, the neural network showed higher computational reliability compared to the parallel algorithm for solving the differential equation. It should also be noted that the conclusions based on the results of the study of the reliability of the neural network calculation system should be understood in a statistical and not an absolute sense
Justification of key factors regarding the application of prospective ecological transport in the urban passenger transportation system
Authors: Deryugin O. , Stolbchenko O. , Liabakh D. , Cheberiachko L.
Published: September 2024

Research objective. Justification of the key factors that have an impact on the introduction of promising ecological transport in the system of urban passenger transport in order to improve the quality of transport services for passengers and improve ecology in densely populated cities. Materials and methods. To achieve the goal, the fuzzy Dematel method is used, which is based on graph theory and allows to classify all available factors that influence decision-making based on cause-and-effect relationships. Results. The eight key factors that form the transport project and the factors that have a significant impact on them are substantiated for the implementation of the transport project of the implementation of promising ecological passenger transport on urban routes into the transport system of urban passenger transportation. These include the level of development of modern transport technologies when transporting passengers on city routes and the availability of their support centers; the availability of financial programs for updating/restructuring the rolling stock fleet of the motor vehicle enterprise and the availability of the appropriate legal framework for preferential operation of electric passenger transport; rapid adaptation of the transport infrastructure of a modern city for the operation of ecological transport; compliance of ecological transport with the transport characteristics of the passenger transportation route; operational properties of a modern electric bus; the effect of relevant legislative initiatives regarding benefits for the purchase and costs of operating electric vehicles. Scientific novelty consists in identifying the interrelationships between the factors that form the transport project and the factors that have a significant influence on them, on the implementation of the transport project of the implementation of promising ecological passenger transport on urban routes into the transport system of urban passenger transport, which allows to estimate the possible economic costs of road transport enterprises carrying out passenger transportation. Practical significance lies in the determination of key factors that can be used for the implementation of a transport project for the use of promising ecological passenger transport in the system of urban passenger road transport
Main directions for improvement of navigation safety through prevention of ship collisions
Authors: Kalinichenko T.V.
Published: September 2024

The article is devoted to the study of the main directions of improving the safety of navigation by preventing ship collisions. The modern development of global shipping is characterized by an increase in the intensity of maritime transportation, which significantly increases the risks of emergencies, in particular ship collisions. These incidents are one of the main causes of maritime accidents, resulting in significant economic losses, environmental damage and risk to human life. The article analyzes various aspects of improving safety of navigation, including the use of modern technologies, organizational measures, crew training and efficient ship maintenance. The focus is on the following areas: technical support, organizational measures, education and training for the crew, communication systems and international coordination, as well as ensuring the technical serviceability of ships. Radar systems allowing to detect and track ships at different distances, which is critical in difficult weather conditions. Another important aspect is crew training. Regular professional education, training, and simulation training help crews adapt to new technologies and respond effectively to dangerous situations. An effective communication system and international coordination are critical for rapid response to emergencies. Emergency communication systems ensure rapid exchange of information between ships and coastal services, and international cooperation contributes to increased preparedness and coordination. Ensuring the technical serviceability of ships through regular inspections and technical surveys is the basis for safe navigation, allowing to identify and eliminate potential problems. The article emphasizes the importance of a comprehensive approach to improving shipping safety, including the integration of advanced technologies, organizational processes, training and maintenance. This approach helps to reduce the risk of ship collisions and improve overall safety at sea
Modified Successive Approximations Method for Solving Fuzzy Second Kind Fredholm Integral Equations with Separable Kernel
Authors: Ababneh Jiana , Zureigat Hamzeh
Published: September 2024

This paper presents an analysis, development, and application of a modified method of successive approximations to solve fuzzy second kind Fredholm integral equations with a separable kernel. The fuzziness in the equations is represented utilizing convex normalized triangular fuzzy numbers, which are based on a single and double parametric form of fuzzy numbers. In the single parametric form of the fuzzy number, a fuzzy equation converts to two crisp equations for the solution which increases the computational cost. Therefore, to reduce the computational cost and increase the solution's accuracy, the double parametric form of the fuzzy number will be used in this study. The feasibility of the proposed methods is illustrated through a numerical example. The results obtained using the presented approach demonstrate adequate agreement with relevant theoretical aspects.
PENGARUH FILM PENDEK DALAM LAYANAN INFORMASI UNTUK MENINGKATKAN PERILAKU DISIPLIN SISWA DI SMP N 19 KOTA JAMBI
Authors: Muhammad Shafari Apri , Rasimin Rasimin , Yaksa Rully Andi
Published: September 2024

The phenomenon at SMP Negeri 19 Jambi City is that there are students who lack discipline which can hinder their learning process. The aim of this research is to reveal the influence of short films in information services to improve student disciplinary behavior.This research uses a Quasi Experimental Design type or quasi-experimental research using Pretest Posttest one Group Design. The population in this study was 245 class VIII students. The sample in this study was 31 students taken using purposive sampling technique. The instruments or data collection tools used were interviews, observations and questionnaires. Data were analyzed using percentage calculations with formula C, normality test, and t- test.The results of this research show that the disciplined learning behavior for the pretest was 3997 and for the posttest it was 4664. Based on the results of the t-test calculations, the T count was 9.416. The value of Ttable is 2.045 with a Sig value. (2-tailed) 0.000 ie. It can be seen that Tcount > Ttable so that the hypothesis is stated that there is a difference between pretest and posttest (before and after treatment is given). Based on the results of the treatment, it was stated that H₀ was rejected and Hₐ was accepted. So it can be concluded that there is a positive and significant influence of short films in information services to improve student disciplinary behavior.
TERAPI COGNITIF BEHAVIOUR THERAPHY BAGI INDIVIDU YANG MENGALAMI STRESS
Authors: M Kis M Kis , M Syaddam Husein , Masril Masril
Published: September 2024

This research aims to provide intervention to teenagers who easily experience stress when facing problems in their daily lives. This stress behavior can be seen in his daily activities, he is irritable, anxious, restless, easily angry even over trivial things. The subject felt offended if he saw a friend whispering, the subject felt that he was the one being talked about, the subject once had a fight with a friend just because the friend accidentally nudged him while he was standing, the subject once fell unconscious like a person possessed because there was a problem with his mother. This habit disrupts social relations and it is not uncommon for the subject to become stressed and fall ill when he or she experiences a lot of problems. This behavioral therapy involves cognitive steps related to the influence of irrational beliefs about problems that always bother the mind. The cognitive therapy process can help subjects to understand certain cognitive problems in carrying out the actions necessary to fulfill commitments, as well as increase the individual's willingness to engage in more adaptive behavior. In this study, cognitive therapy ran for 8 meetings. With 7 steps which involve CBT counseling, writing a daily diary based on the ABC format of CBT theory and the last step is a relaxation technique. The result of cognitive therapy is that the subject can reduce and become aware of the cognitive distortions that have disturbed his social life so far
Teori Belajar Konstruktivisme dalam Perkuliahan Keanekaragaman Tumbuhan
Authors: Fitri Rahmadhani , Jamaris  , Solfema
Published: September 2024

Interaksi belajar mengajar (pembelajaran) merupakan satu bentuk proses pendidikan. Pola pembelajaran ini bisa dipengaruhi oleh penampilan pendidik dalam mengajar. Pendidik di perguruan tinggi dikenal dengan sebutan dosen. Penampilan dosen dalam memberikan perkuliahan dapat didasari oleh pengetahuannya terhadap teori belajar. Pelaksanaan pendidikan terutama dalam proses pembelajaran sangatlah terpengaruh oleh teori belajar dan pembelajaran. Teori belajar merupakan cara menerapkan kegiatan belajar dan mengajar antara pendidik dan peserta didik. Pada prinsipnya, ketika seseorang (pendidik) ingin menerapkan teori belajar, terkadang pendidik menggunakan lebih dari satu teori belajar dalam proses pembelajaran. Penelitian ini merupakan studi literatur dengan menganalisis artikel terkait teori belajar konstruktivisme dan menghubungkannya dengan perkuliahan keanekaragaman tumbuhan. Pembelajaran konstruktivistik lebih menekankan pada proses belajar dan memberikan kebebasan dan kesempatan kepada mahasiswa untuk mengkonstruksi pengalamannya sendiri. Proses pembelajaran yang dilakukan diharapkan dapat menjadikan mahasiswa lebih kreatif dan imajinatif. Hal ini juga dapat menciptakan kondisi lingkungan belajar yang kondusif. Pembelajaran konstruktivisme ini menekankan dan berpusat pada mahasiswa agar mereka aktif dalam proses pembelajaran. Berdasarkan analisis yang telah dilakukan, pembelajaran yang dilakukan pada perkuliahan keanekaragaman tumbuhan sudah menggunakan teori belajar konstruktivisme. Hal ini dikarenakan dalam pembelajaran, metode pembelajaran yang digunakan dosen menekankan pada mahasiswa untuk melakukan proses penemuan dan konstruksi pengetahuan sendiri.