bluuebunny/crossref_metadata_2025 huggingface dataset:
The alterations of serum nitric oxide levels in diabetic retinopathy
Authors: Kurtul Naciye , Aksoy Hülya , Pençe Sadrettin , Bakan Ebubekir , Baykal Orhan
Published: June 2023

Diabetic retinopathy (DR) is one of the major complications of diabetes mellitus. Despite intensive research effort the pathogenic mechanisms important to the initation and progression of DR are stili poorly understood. Endothelial dysfunction has been implicated in the pathogenesis of DR. Nitric oxide (NO) is a potent vasodilator released by endothelial cells that may play an important role in modulating the vascular tone. in this study, serum NO level in samples obtained from Type il diabetic patients with retinopathy was measured spectrophotometricly. Thirtytwo patients that were included in the study, were grouped with respect to the degree of retinopathy. An association between serum NO level of the patients and the degree of retinopaty was sought. The serum NO Ievel in patients with diabetic retinopathy was signifıcantly decreased compare to control group. For this reason it is concluded !hat this change in serum level of NO may have a role in pathophysiology of diabetic retinopathy.
lntracranial hemorrhage caused by vitamin K deficiency in newborn: A case report
Authors: Sivaslı Ercan , Yılmaz Kutluhan , Karaoğlan Murat , Kılınç Metin , Yılmaz Mustafa , Coşkun Yavuz
Published: June 2023

Bleeding caused by vitamin K defıciency (BVKD) is stili an ongoing problem in newborn infants. Three types of BVKD have been described; 1)early, 2)classical and 3) late. lntracerebral hemorrhage, which is the most serious complication of the BVKD, is more frequently seen in !ate form than early and classical forms and, three forms of BVKD is prevented by routine administration of vitamin K (VK) to the newborns. But this easy and cheap method of prophylaxy is not widely known by neither parents nor health providers in developing countries. fn this report, a 4-day-old female infant who was not administrated routine prophylactic VK, and who died from intracerebral hemorrhage due to classicaf type of BVKD. it is emphasized that intracerebral hemorrhage may be seen in classic BVKD and both parents and health providers should be given education to prevent the disease.
Current diagnostic strategies in acute pulmonary thromboembolism
Authors: Dikensoy Öner
Published: June 2023

Nowadays, even in the industrialized countries, pulmonary embolism has signifıcant morbidity and mortality due to delayed diagnosis. On the other hand, some cases expose the risks of anticoagulant chemotherapy due to overdiagnosis. Here, we reviewed the current strategies in the diagnosis of acute pulmonary embolism.
The properties of the the magic cube of fourth order
Authors: Abiyev Asker Ali , Arslan Ahmet , Abiyev Azer , Filiz Hüseyin , Muharremov Akif
Published: June 2023

In this article we present the solution of the magic cube of fourth order made up of natural numbers using the general algorithm introduced by us, and the properties of this cube were analyzed. We noticed that the properties of magic cubes are valid for any nurnbers (rational, irrational, ete). These properties of the magic cube that made up rnagic square slices have shown that there is a strong relationship among the numbers that were assigned to the squares in the cube. Because of this relationship in magic cubes and magic squares the rnass and the geometrical centers are overlaps each other. These are the important findings of the general algorithm that we found.
Prevention of reperfusion induced lung injury by L-carnitine
Authors: Sivrikoz M. Cumhur , Öz Eser , Halit Velit , Altunkaya Aykut , Üstünsoy Haşim , Şenkaya Işık , İmren Yıldırım , Özoğul Candan
Published: June 2023

L-Carnitine plays an important role in the transmembrane transport of long chain fatty ascids for it's oxidation and supresses the development of free radical damage. An experimental comparative study isolated guinea pig lungs has been undertaken to determine the probable beneficial effects of adding L-Carnitine to preischemic pulmonary perfusion solutions in lung ischemia-reperfusion. The isolated lungs (n=10 in control group) previously being perfused by oxygenated Krebs Henseleit solution were put in normothermic ischemic conditions. 1 O mmol of L-Carnitine was added into a Krebs-Henseleit solution in the experimental group (n= 10) and after 20 min., perfusion was completed and the lungs were then exposed to normothermic ischemia. After 3 hours of normothermic ischemia, the lungs were perfused with Krebs-Henseleit solution for 20 minutes. Tissue malondialdehyde (MDA), glutathione (GSH) levels and electron microscopic evaluations were held on before the ischemic period and also at the end of reperfusion. MDA and GSH levels of the perfusate were measured before ischemic period and at the end of reperfusion. L-Carnitine administration reduced MDA levels both in tissues and perfusates. in contrast to glutathione levels which is increased. According to our data, the addition of L Carnitine to preischemic pulmonary perfusion solution showed a significant protective effect regarding both ischemic and reperfusion injury.
Comparison of anteroposterior and lateral lumbar spine DEXA measurements in postmenopausal women
Authors: Zincirkeser Sabri , Çelen Zeki , Yılmaz Mustafa , Gürsoy Savaş
Published: June 2023

The purpose of this study was to evaluate diagnostic sensitivity of lateral (LAT) spine bone mineral density (BMD) measurements which were performed by DEXA (Dual Energy X-ray Absorbsiometry) and compare to anterior-posterior (AP) spine BMD in postmenopausal women. One hundred and three postmenopausal women were studied. Osteoporosis was diagnosed by standard AP position (T< - 2.5) and then BMD was measured by LAT position. Subjects are divided into two groups according to their ages ( between 50-60 age and over 70). BMD percentage difference between the two groups found 11.69 % for AP L2-L3, 29.84% for LAT L2-L3. There was a significant difference between mean values of the two groups (p < 0.05). Decrease in BMD related to age is more prominent in LAT position compared to AP position. Diagnostic sensitivity is measured by the Z score method. When AP and LAT measurements are compared for both groups, LAT measurements showed lower diagnostic sensitivity (AP mean Z score : -2,5 ± 0,852 ve LAT mean Z score: -1,9± 0,822 ). As a result of this study, LAT spine position had lower diagnostic sensitivity according to AP position. We think that LAT spine position should be used as a complementary procedure in the evaluation of BMD.
Evaluation of conventional selective suture cutting in astigmatism following cataract surgery with simple analysis
Authors: Erbağcı İbrahim , Güngör Kıvanç , Bekir Necdet
Published: June 2023

We planned this study to investigate the optimum time to put into practice conventional selective suture cutting method, which has been used world-wide, easy to do and cheap technique for astigmatism occurred after cataract surgery. In this retrospective study, 136 eyes of 130 cases, all have no previous surgery or another eye disease except senile cataract and controlled regularly for 6 months were divided into three groups. Early suture cutting technique was used in group I, routine suture cutting technique (in 2nd or 3rd month) was used in group II and no suture cutting technique was used in group III. Postoperatively after 1 week, in all groups there were significantly high astigmatism (group I: 7.23±1.72D; group II: 6.65±1.27D, group III: 6.87±2.1D, p<0.05), those have similar astigmatism before the surgery in all groups (group I: 0.56±0.51 D; group II: 0.65±1.27 D, group III: 0.67±0.47 D). Postoperatively third and sixth months astigmatism had fell down in all groups. Although there were more decreases in astigmatism in group I and group II than group III, (postoperatively 6th month, group I: 1.98±1.76D, group II: 2.52±1.86D, group III: 3.67±1.82D, p<0.05); the difference between group I and group II was not statistically significant (p>0.05). In our opinion that easy, practical and harmless conventional selective suture cutting technique can be applied as early 1 month after cataract surgery for disturbing from astigmatism which occurred postoperatively.
Molecular genetic diagnosis and clinical applications in medicine
Authors: Pehlivan Sacide
Published: June 2023

There has been an amazing increase in our acquiring genetic information by means of the technological developments and the completion of the human genome project in a shorter time than expected. Within the light of this information, there has been a great change in approaching human health and diseases. Having developed rapidly within the last 20 years, the new genetic technology provides many opportunities of test for the prevention, diagnosis and treatment of diseases. Today it is known that there are 900 to 1000 genetic tests used in routine diagnosis. Clinicians should learn this new technology and approach in a very short period of time and use them for the benefit of their patients. Molecular Genetic Diagnosis and Clinical Applications in Medicine will be reviewed in this collection.
Hepatitis B seroprevalance in persons admitting to check-up clinics of Kahramanmaraş Sütçü İmam University Medical Faculty
Authors: Çelik Mustafa , Ekerbiçer Hasan Çetin , Çetinkaya Ali , Büyükbeşe Mehmet Akif , Aral Murat
Published: June 2023

The aim of this study is to find out the HBV seroprevalance in the people admitted to Kahramanmaraş Sütçü İmam University Medical Faculty Check- up clinics. Demographic features and HBV vaccine status of 377 cases who admitted to the check-up clinics of Kahramanmaraş Sütçü İmam University Medical Faculty Hospital, were questioned and the blood samples of each patient were collected. Serum HbsAg and Anti-HBs parameters were evaluated by Access IEIA (Immunoenzymatic ""sandwich"" Immunoassay) method. The cases with positive HbsAg were encountered as HBV carrier. 221 of the cases (58.6%) who enrolled in the study were female, 156 (41.4%) were male. Mean age was 39.2±12.5. Three hundred and two (96.1%) were having social insurance coverage. Numbers of the known hepatitis B carrier as HbsAg positive were 16 (4.2%) and immunized (Anti-HBs positive) ones were 50 (13.3%). Twelve cases (3.2%) had the history of hepatitis B vaccination. All the cases who had vaccination were immunized and these were consistng 24 % of Anti- HBs positive persons. Social and cultural levels of the patient admitted to the check-up clinics were higher comparing with whole population living Kahramanmaraş. For this reason we conclude relatively lover seroprevalance of HBV does not reflect the true prevalence of the virus of the people living Kahramanmaraş.
Evoluation of HBV Antibodies Evoked by Immunization And Infection Among Health Employee and Population
Authors: Karsligil Tekin , Uygur Oktay
Published: June 2023

In present study HBV-markers (HBs Ag and Anti HBs) were investigated in two different groups. HBV antibodies evoked by immunization and infection in health employees and population were researched and compared each other. From January 1998 to January 2000 we investigated hepatitis B virus markers (HBS Ag and Anti HBs) by ELISA technique (Bioelisa, Biokit S.A., Spain) in total of 248 persons, 100 from normal population and 148 from healthy hospital employees. Following detection of HBV markers, HBV vaccine (GenHevac B, Pasteur) was administered in 96 subjects with being seronegative of HBs Ag and Anti HBs. Serum samples were collected on the 30th days of postvaccination for Anti HBs response. In the group of healthy hospital employees, the frequency of positivity for HBs Ag and Anti HBs antibodies was 35.14 % (52 of 148) and 5.41 % (8 of 148) respectively. At the same time HBs Ag and Anti HBs positivity were 5 % (5 of 100) and 26 % (26 of 100) in healthy population. There weren't any immunization occur after the first dose of vaccination. One month after the second dose, 3 subjects of hospital employees and one subject of healthy population and one month after the third dose, almost all subjects (except one in hospital employees) were being seroprotected. Hepatitis B virus is a common viral agent; so vaccination has been seemed to be necessary in order to eradicate Hepatitis B infection. The vaccine should be applied at high risk groups especially in health workers before beginning working. In this study it has been shown that the first and second dose of vaccine were insufficient in developing Anti HBs antibodies. In conclusion three doses immunization course against HBV were necessary to elicit protective levels of Anti HBs antibodies.
The Relationship Between The Age and Sex and The Plasma Zinc and Cupper Level in Type 2 Diabetes Mellitus Patients
Authors: Kurtul Naciye , Pençe Sadrettin , Çil Yaşar , Aksoy Hülya , Erman Fazilet
Published: June 2023

The study was carried out in patients with Type II Diabetes Mellitus (DM) in order to investigate two important elements in serum levels of zinc (Zn) and copper (Cu). This study included 112 diabetic patients, In addition, 210 healthy volunteers were taken as the control group.The serum Zn and Cu levels were determined, after dilution of samples with atomic absorption spectrophotometry (AAS). The obtained results were evalueted with respect to according to sex and age groups. Serum Zn levels significantly lower in the diabetics patients than controls as p<0.001. Serum Cu levels were found to higher in the diabetics (p<0.001). Similar results were found when the subjects were evaluated in terms of age groups. However, in both the patient and control group (p>0.05). Conversely, both the female controls (p<0.001) and female diabetics (p<0.005) had higher serum Cu levels than those of the male ones. In addition in each age group, female subjects had higher serum Cu levels than those of the male subjects both in the control and patient groups. Serum Cu levels were found to be increased with age and there was a significant correlation between the age and copper values (p<0.01). As a result serum Zn levels of diabetic patients were found to be lower than that of healty people contradictory to serum Cu levels which were found to be higher in diabetics. The change in Zn and Cu levels in diabetics show that these elements are important in occurence of diabetes mellitus.
Fibrin Glue Injection in the Treatment of Fistula-in-Ano: A Non-Invasive Alternative Technique
Authors: Kaplan Mehmet , Salman Bülent , Menteş Bülent
Published: June 2023

The goal of the study was to demonstrate whether injection of commercially available fibrin glue would be effective as an alternative treatment in closing the tract of the fistula-in-ano. Twenty-one patients with anal fistula were included to the study. There were 4 simple, 7 trans-sphincteric, and 10 inter-sphincteric fistulas. Ten of 21 patients had recurrent fistula. Fibrin glue was injected until it seen overflowed from the primary opening which then secured with two or three absorbable suture material. Follow-up visits were scheduled at one week, 1,3,6, and 12 months. All patients were followed-up at least 12 months. A complete healing was achieved in 14 patients in the first injection. Of the recurred seven patients 2 also had complete closure after second attempt; as a result, overall in 16 patients (76.2%) fibrin glue injection was found to be effective. Failure was observed in 5 patients (23.8%). There was no association between fistula types and recurrence; furthermore, the success rate of fibrin sealant was not affected either by sex, or by previous recurrent fistula (p>0.05). Fibrin glue can be used safely in the treatment of anal fistulas, especially in recurrent and difficult cases. We recommend this technique, as a first choice of treatment in the patients with complex fistula and in whom the surgeon suggested the anal functions would be compromised when conventional surgery carried out.
Effect of Oophorectomy and Exogenous Estrogen Replacement on Liver Injury in Experimental Obstructive Jaundice
Authors: Uçan Hamdi Bülent , Kaplan Mehmet , Menteş B. Bülent , Salman Bülent , Pençe Sadrettin , Aybay Cemalettin , Akyol Gülen
Published: June 2023

Bu çalışmanın amacı, cerrahi uygulamada sıklıkla karşılaşılan deneysel bir obstrüktif sarılık (safra kanalı tıkanıklığı) modelinde östrojenin karaciğer hasarı üzerindeki rolünü araştırmaktır. Üç grup dişi sıçan oluşturuldu; grup 1'e ooferektomi yapıldı ve E2 (n=14), grup 2'ye ooferektomi ve plasebo verildi (n=14), grup 3'e kan östrojen düzeyini normal aralıkta tutmak için sahte ameliyat edildi (n=14). Tüm gruplarda safra kanalı ligasyonunun oluşturulmasından 14 gün sonra serum testleri ve histopatolojik parametreler değerlendirildi ve ELISA yöntemi ile IFN-gama ve IL-6 doku düzeyleri ölçüldü. Daha sonra tüm gruplar karşılaştırıldı. Serum GGT ve ALT düzeyleri grup 1 ve 3'te grup 2'ye göre anlamlı derecede yüksekti (p<0.05). Hem yaralanmayı hem de reaktif yanıtı ve iyileşmeyi temsil eden parametrelerin grup 1 ve 2'de daha belirgin olduğu bulunmuştur (p<0.05). Sahte ameliyat edilen veya E2 verilen gruplarda anlamlı olarak daha düşük IFN-gama doku düzeyleri ve daha yüksek IL-6 düzeyleri bulundu, bunun aksine ooferektomize ve plasebo verilen grupta yüksek IFN-gama ve düşük IL-6 doku düzeyleri bulundu (p<0.001). Kupffer hücre değişikliklerinin grup 1 ve 3'te daha belirgin olduğu gözlendi (p<0.05). Çalışmamız, E2'nin karaciğer fonksiyonlarını bozduğunu, hem karaciğer hasarını hem de iyileşmeyi hızlandırdığını göstermektedir. Safra kanalı tıkanıklığı koşullarında, östrojen karaciğerdeki sitokin ortamını önemli ölçüde değiştirdi ve ayrıca sitokin ortamını değiştirebilen Kupffer hücreleri yoluyla karaciğer hasarını değiştirebilir.
Vancomycin Induced Thrombocytopenia in a Newborn
Authors: Çöl Araz Nilgün , Balat Ayşe
Published: June 2023

Severe thrombocytopenia due to vancomycin is a rare complication reported in both the pediatric and adult population. In this paper, we present a case of thrombocytopenia due to vancomycin in a newborn. Ceftriaxon and ampicillin-sulbactam were administered to a 20-day-old boy with diagnosis of bronchopneumonia and sepsis. On the 7th day, vancomycin was added to the treatment because of worsening clinical picture. 48 hours later, the patient showed significant clinical improvement; however, on the 4th day of the vancomycin treatment, thrombocytopenia was developed (25,000 cells per mm3). The antithrombocyte antibodies were negative. After stopping the vancomycin treatment, the thrombocyte count rose to more than 100,000 within four days. In newborns, no thrombocytopenia case has been reported to date. In the pediatric population, thrombocytopenia is rare, but it can be a fatal condition. So newborns who have been given vancomycin should be closely followed for vancomycin-induced thrombocytopenia.
Epithelioid Malignant Peripheral Nerve Sheath Tumor In Perineal Region
Authors: Anlatıcı Recep , Kayaselçuk Fazilet , Akçalı Cenk , Noyan Turgut
Published: June 2023

Epithelioid malignant schwannoma is an uncommon variant of malignant schwannoma. There are a few published articles about epithelioid malignant schwannoma in literature. A 38- year-old woman who had a necrotic and ulcerated, bad smelt mass with a size of 30x25x20 cm, at her right perineal region that invaded right labium majus was hospitalized. The patient was underwent large resection and ipsilateral inferior epigastric artery based vertical rectus abdominis musculocutaneous flap to reconstruct the defect. The patient referred to the Oncology Department for chemotherapy. She died within 3 months after the first operation. because of metastasis.
Subacute Sclerosing Panencephalitis
Authors: Ölmez Akgün
Published: June 2023

Subacute Sclerosing Panencephalitis is one of the progressive, fatal slow virus infections of the central nervous system caused by a defective or mutant measles virus. Diagnosis is based on the typical clinical features and elevated measles antibody titers in the cerebrospinal fluid. Possible underlying mechanisms of SSPE which is one of the long-term complications of measles infection in measles contracted children, clinical fetaures of SSPE patients and current treatment options will be reviewed.
Determination Of Women's Knowledge, Attitude And Behaviours About The Self Examination Of Breast
Authors: Güner İlkay Coşkun , Tetik Aynur , Gönener H. Demet
Published: June 2023

Cancer and other health problems about breast that are very important for women's health and aesthetic are frequent problems. Therefore, self examination of breast has great importance in determination of a pathology in breast. Performing the education role that is one of the modern roles of the nurse in a professional why is therefore very important in the protection of our women's breast health.The study was done between 218 women, aged between 15-49 years who were admitted two health centers. Data was collected from a questionnare composed of 15 questions and was evaluated by SPSS programme. It was found that 44.7% of the study population were between 25-34 years old, 52% of them were primary school graduate, 94.5% of them were married, 82.2% of them were living with their care family. It was also determined that 5% of the women have never heard of self examination, 29.2 % of the ones that know self examination have heard it from a nurse, 50.2% of them does not know how to do it and 52.1% of them have never done self examination. As the education level of the women increased, knowing, hearing and performing self examination had improved. Regarding the social importance of women's health, we suggest that nurses should do more training.
The Relationship Between Minor Histocompatibility Antigens And Graft-Versus-Host Disease After The Allogeneic Hematopoietic Stem Cell Transplantation
Authors: Kekik Çiğdem , Beşışık Sevgi , Sargın Deniz , Çarin Mahmut N. , Oğuz Fatma S. , Seyhun Yalçın
Published: June 2023

The major complication of hematopoetic stem cell transplantation (HSCT) is graft-versus-host disease (GVHD) or graft. HLA incompatibility increases the frequency of GVHD. On the other hand, the risk is still available despite full matched HLAs, which may be related with non-HLAs or minor antigens. One of these minor antigens, HA-1 alelic incompatibility has been shown to be associated with GVHD in HLA-identical sibling transplants. The HA-1 is an HLA-A*0201 restricted non-peptide, which derives from the cleavage of a protein encoded at chromosome 19. There are two aleles of HA-1 created by a polymorphism at position 504 that results in either Histidine (HA-1H) or Arginine (HA-1R). The aim aof the study is investigate the relationship between HA-1 and GVHD. We retrospectively examined the HA-1 locus in patients diagnosed and treated between 1998-2004. We used PCR-SSP for typing HA-1. Forty samples from 20 HLA-A2 positive HSCT (BMT, n=3 ; PBSCT, n=17 ) recipients and their donors were included in our study. The frequencies of the three possible genotypes RR, RH, HH were 35%, 45% and 20%, respectively, in recipients and 35%, 65% and 0% in donors. Four of the 20 patients (20%) were determined as having evre II or III GVHD. There is HA-1H incompatibility between donor and recipient only in two patients with GVHD. mHAgs were found to be incompatible in 8 out of 20 recipient/donor pairs.
The Comparison of the Urea Breath Test and the Rapid Casette Test (Card Test) in Diagnosis of Helicobacter Pylori
Authors: Mehli Murat , Karslığil Tekin , Akgün Sadık , Koruk Mehmet
Published: June 2023

The purpose of this study is to determine sensitivity of the rapid H. pylori casette test in patients who were admitted to hospital with epigastric pain, and who were diagnosed with H. pylori positivity with the urea breath test, and to also analyze the role of the two tests in diagnosis. A total of 149 patients, 71 (48%) males, and 78 females (52%) with an average age of 41, who were admitted to Gaziantep University Faculty of Medicine Gasroenterology Polyclinic with epigastric pain were included in the study. The urea breath test was applied to the patients and separating serum from venous blood which was taken simultaneously, with the chromatographic immunoassay method (Cart test) (Medisera Diag. Inc., Canada) serum IgG levels were detected. The results of the urea breath test and card test were compared. A total of 91 (61%) of the 149 patients who were admitted to hospital with epigastric pain H.pylori urea breath test were positive; 128 (86%) of the patients who were examined with the rapid cassette test were detected as positivite. In 7 (8%)of the 91 patients who were found to be positive with the urea breath test, the card test was found to be negative, and in 44 (78%) of the 58 patients who were detected negative with urea breath test, positivity was detected with the card test. In diagnosis of H.pylori, a statistically significant difference was found between the urea breath test and the rapid H. pylori cassette test. When compared with the urea breath test, the specificity, sensitivity, positive predictive and negative predictive values of the rapid H.pylori card test was found to be 21.4%, 92.3%, 65.6% and 79.1 respectively. When the results were assessed considering factors such as the possibility of a late antibody response and its persistency, as well as negative effects of antibiotic and/or proton pump inhibitors, it was thought that using the chromatographic methods in seroepidemiologic studies rather than diagnosis would be more convenient.
Effect of Varicocele on Testicular Volume
Authors: Kervancıoğlu Selim , Sarıca Akif , Mete Ahmet , Özkur Ayhan , Bayram Metin
Published: June 2023

Varicocele is one of the common causes of male infertility and is characterized by an anomalous dilation of the veins of the pampiniform plexus. There are many researches reported about ipsilateral testis volume reduction in varicocele in the literature. There are few researches reported about the effect of varicocele to the contralateral testis and different results have been reported unlike each other, as some reports say that an increase in contralateral testicular volume in varicocele, the others say reduction in contralateral testicular size. In our study we aimed to detect the effects of varicocele on bilateral testicular size. The study included 89 adult patients that had undergone routine scrotal CDUS and diagnosed with only left-sided varicocele. 51 patients which have no varicocele and any other anomaly with testis were chosen for the control group. The patients diagnosed with varicocele gathered into groups as grade 1, grade 2 and grade 3. The difference between bilateral testis volume was calculated by the formula; [(right testis volume-left testis volume) / right testis volume x 100] in all patients. Right and left testis volumes, volume differences between testes among all groups (control, grade 1, grade 2 and grade 3 groups), and right and left testis volumes in each group were compared. No significant difference was established statistically in comparision of testis volumes in each group, and right and left testis volumes and differences between testes volumes within groups. In conclusion, our study established that there is no effect on testis volume in varicocele.
Iliac Artery Injury With Foreign Body: A Unique Case Of Child Abuse
Authors: Baransel Isır Aysun , Tokdemir Mehmet , Parmaksız Ergün , Rahman Ali , Kazez Ahmet
Published: June 2023

The aim of this study is to discuss physical abuse part of a case by presenting a rarely seen injury which is vaginal bleeding 8-month-old girl with an unknown story. At further analyze and operation, she was operated on for a 4.2 cm long foreign body which caused both perforation in the uterus and injury to the right iliac artery. Four days after the operation, she had sudden loss of vision, intracranial bleeding and generalized convulsion. Three months later, it was encountered that she had an amputated distal phalanx in the 5th finger on the right hand. Social and medico-legal management of physical abuse is suboptimal in Turkey. In this way, an emphasis is made on the necessity of subject keeping in mind when injuries without any sufficient reliable data are encountered as the physical abuse.
Globalisation, Health And Society
Authors: Yıldız Özkan
Published: June 2023

Neo-liberalism includes every aspect of life to its own functioning conditions. During the last two decades, the gains of a welfare state, (i.e. health service, education and social security services) have been observed suffering from economic crisis. As a matter of fact that health services have subjected to the requirements of market economy, in addition to that government have decreased their budgets which have previously allocated to the health services. The prominent examples which leave health services in the hands of private marketing are the health services have been transferred to the market economy, the trend in private health care, the flexibility in laboring. As a result of these privatization policies, there have been great troubles in supplying health services as well as preventive health services. The present article investigates the probable influence of 'neo-liberal policies' on the health services.
Angiotensin Converting Enzyme Gene Polymorphisms In Male Infertility
Authors: Pehlivan Sacide , Onay Hüseyin , Tavmergen Erol , Tavmergen Göker N. , Çoğulu Özgür
Published: June 2023

The aim of this study was to investigate the frequency of Angiotensin Converting Enzyme (ACE) polymorphism in patients with oligospermia or azoospermia and to compare the frequency of polymorphism with the control group which included the men who had a child within 5 years. ACE insersion (I) / deletion (D) polymorphism was investigated at 132 men; 71 of them were diagnosed as azoospermia, 31 of them were diagnosed were oligospermia and 30 of them were healthy control. Analysis revealed that azoospermic, oligospermic and controls in terms of polymorphisms, genotype and allele frequencies, the differences were not significant and were no deviations from the Hardy-Weinberg equilibrium. The DD polymorphism ratio was found to be low (27.5%, p<0.05) in the individuals diagnosed with oligospermia in comparison to normal and azoospermic males; however, this difference was not istatistically significant and it was attributed to sampling size could have provided significant relationship.
Ureteroscopic Treatment Of Ureteral Calculi Our Results Of Multiaspect Evaluations In 1265 Patients
Authors: Erturhan Sakıp , Sarıca Kemal , Yağcı Faruk , Erbağcı Ahmet , Seçkiner İlker , Özgül Hanifi
Published: June 2023

In our study, the results of rigid ureteroscopy in the management of stones located in different segments of the ureter is being presented. Between 1995-2005, totally 1265 patients with ureteral stones (742 male, 523 female) with an avarage age value of 42.5 (ranged 18-74) years have been treated with rigid ureteroscopy. Depending on the size as well as their impaction to the ureteral wall, they were either directly removed by basket catheters or pneumatic lithotripsy has been used for disintegration of the stones. Success rates obtained with respect to stone location as well the irrigation fluid used and the operational time, auxiliary procedures and that of complication rates were comparatively evaluated. Stone size ranged from 0.4 to 2.3 cm (mean 1.4). While 459 (36.3%), stones were removed by ureteroscopy with basket application, pneumatic lithotripsy were necessary in 739 (58.4%) cases. Mean operation time was 25.4 (ranged from 9 to 39) minutes. In 1198 (94.7%) cases have been completely stone free after the procedure. In 67 cases (5.3%), the procedure was unsuccessful. Ureteral stent was applied in 243 cases following stone removal (19.2%). Our results have demonstrated that, ureteroscopy is a safe and effective manner in the treatment of ureteral stones. We believe that, this procedure should be the first treatment of choice in the management of the stones located especially in the lower part of the ureter when compared with ESWL (Extracorporeal Shock Wave Lithotripsy). Additionaly, this procedure can also be applied in mid and upper ureteral stones in skilled hands with enough experience.
Fetal Rhabdomyoma: Prenatal Diagnosis And Postnatal Outcome
Authors: Başpınar Osman , Celkan Adnan , Adlı Mustafa , Yılmaz Kutluhan , Kervancıoğlu Selim
Published: June 2023

Fetal kardiyak rabdomyom çok nadir görülen bir durumdur. Bu yazıda, 38. gebelik haftasında prenatal ultrasonografi ile uteroda saptanan kardiyak kitleli bir olgu sunulmuştur. İnterventriküler septumun üçte ikisinde dev bir ekojenik kitle gözlendi. Hasta tüberoskleroz ne olursa olsun ekokardiyografi, fizik muayene ve kraniyal tomografi ile üç yıl takip edildi.
Multiple Drug Ingestion For Suicidal Purpose: Alprazolam, Citalopram, Risperidone, Oxcarbazepine And Alcohol
Authors: Mızrak Ayşe , Koruk Senem , Gül Rauf , Ganidağlı Süleyman , Öner Ünsal , Akın Aynur , Esmaoğlu Aliye
Published: June 2023

Hipnotik ajanlar, antidepresan ve antipsikotik ilaçlar uykusuzluk, depresyon ve psikotik bozuklukların tedavisinde yaygın olarak kullanılmaktadır. Bu ajanlarla aşırı doz alımı giderek daha fazla bildirilmesine rağmen, şimdiye kadar alprazolam, sitalopram, risperidon, okskarbazepin ve alkol dahil olmak üzere birlikte alım vakası gösterilmemiştir. Gelişmekte olan ülkelerde bu ilaçların reçete kullanımı artmaya devam ettikçe, klinik toksisitelerini ve klinik yaklaşımlarını değerlendirmek gerekmektedir. Bu çalışmada, 20 yaşında intihar amaçlı alprazolam, sitalopram, risperidon, okskarbazepin ve alkol içeren ve destekleyici tedavi ile iyileşen aşırı doz olgusu sunulmuştur. Oda arkadaşı ve hastası tarafından bilinçlendiğinde yüksek dozda alprazolam (18 mg), sitolapram hidrobromur (80 mg), risperidon (16 mg), okskarbazepin (600 mg) ve alkol aldığı bildirildi. Standart detoksifikasyon prosedürleri ve destek tedavisi ile tedavi edildi.
The Nurse Factor In Pain Therapy
Authors: Pirbudak Çöçelli Lütfiye , Bacaksız Behiye Deniz , Ovayolu Nimet
Published: June 2023

Multidisciplinary approach is mandatory for pain management. Nurses play a key role in this well organised team work. So, they need to have sufficient knowledge, ability and experience on the mechanisms, evaluation and control of pain. In this article, following the general knowledge on definition and classification of pain, "the nurse factor" in pain control will be reviewed.
Chromium Associates With Insulin Sensitivity
Authors: Geyikli İclal , Bayıl Sibel
Published: June 2023

Chromium has been known to be an essential micronutrient in human nutrient for long times. Recent studies have shed light on a potential role of chromium on carbohydrate metabolism. It has suggested that chromium is effected to insulin by increased of insulin receptor molecule and contribute to adjust blood glucose. We suggested that chromium is remarkable for diabetes's control.
Editör'den
Authors: Balat Ayşe
Published: June 2023

Sevgili Meslektaşlarım,
Dergimizin 4. sayısında buluşabilmenin mutluluğunu yaşarken, hepinizi sevgi ve saygıyla selamlıyorum.
Tıp eğitiminin temelinde usta-çırak ilişkisi önemlidir, ancak teknolojik gelişmelerin hızla devam ettiği dünyada "usta" olduktan sonra da yenilikleri takip etme ihtiyacı kaçınılmazdır. Yeniliklerin takibinde ve eğitim-öğretimin temelinde ise iletişim vardır. Bilimsel dergiler de bu iletişim ağının önemli unsurlarından biri olup, "olduğuyla yetinme tehlikesi"yle mücadele etmektedir. 4000 yıl önce, Sümerli bir eğitmen ve şair olan Ludingirra "Madem ki biliyorsun, niye öğretmiyorsun" diyerek, bilgi akışında eğitimciler arasındaki iletişimin önemini vurgulamak istemiştir.
Bu süreçte, dergimiz aracılığıyla yenilik ve tecrübelerin paylaşımına katkı sağladığımızı umar, dergimizin hem ''çıraklar'' hem de "ustalar" için yararlı olmasını diler, bir sonraki sayıda buluşabilmek umuduyla sevgi ve saygılarımı sunarım.
 
Prof. Dr. Ayşe Balat
Editör
 
''Tıbbın şansı devamlı ilerlemesidir. Çünkü her zaman öğrenecek çok şey vardır.''
William J. Mayo (Amerikalı cerrah, 1861-1939)
Accelerated Rehabilitation Programme After Arthroscopic Reconstruction Of Anterior Cruciate Ligament
Authors: Altındağ Özlem , Kocabey Yavuz , Soran Neslihan , Tabur Hasan
Published: June 2023

Rupture of anterior cruciate ligament is a common injury during both sports and leisure time activities. Recently attention has been focused on the use of accelerated rehabilitation protocols after anterior cruciate ligament reconstruction. The goal of the rehabilitation after ACL reconstruction is to return to the preinjury activity level as fast as possible. The study was designed to evaluate accelerated rehabilitation programme for final knee function in patients who had ACL reconstruction. A total of 26 patients who had arthroscopic reconstruction after ACL rupture were included in the study. Accelerated rehabilitation programme was applied to all patients. The patients were reexamined on 12th week and 24th weeks. Rehabilitation programme included progressive increase in range of motion, full unassisted weight bearing, and return to participation in daily living. After explaining the exercises, the number of exercise sets and repetitions were prescribed to all patients. It was observed that the patients returned to their daily living activities on 12th week after reconstruction. Complications such as effusion, pain and stiffness of the knee joint were not observed. In conclusion, we suggest that accelerated rehabilitation is effective for early recovery of knee joint functions.
Demographic Features Of Children With Cerebral Palsy In Şanlıurfa And Neighbor Counties
Authors: Altındağ Özlem , Soran Neslihan , Akcan Sait
Published: June 2023

Serebral palsi çocukluk çağında en sık görülen özürlülük nedenidir. Serebral palsinin etyopatogenezinde çeşitli faktörler vardır. Etiyolojinin, hastalığın tipinin ve ilişkili klinik özelliklerin değerlendirilmesi rehabilitasyon programının sonucu ve ailenin katılımı açısından önemlidir. Bu çalışma, Şanlıurfa ve çevre ilçelerinden 50 serebral palsili hastanın demografik özelliklerinin belirlenmesi amacıyla planlandı.
Forensic Medicine View To The Diathermy Burn
Authors: Baransel Isır Aysun , Akbaba Murat , Coşkun Ayşe Gül , Dülger Hikmet Ergin
Published: June 2023

The false steps in monopolar diathermy application causes a situation called the "Diathermy Burns". In this report, while describing our first diathermy burn case also wanted to attract attention to the judicial dimension of the subject. A twenty eight years old female patient that consulted to Gaziantep University Forensic Medicine Department, develops intraoperative electrocouter burn while having an rhinoplasty operation because of septum deviation and noticed it postoperative sixth hour has been presented.
 
Key Words: Diathermy, Electrocouter, Burn, Forensic Medicine
Anesthetic Management Of A Morbidly Obese Patient With Supracondylar Femur Fracture
Authors: Mızrak Ayşe , Işık Mustafa , Koruk Senem , Gül Rauf , Ganidağlı Süleyman , Demir Halit , Öner Ünsal
Published: June 2023

To our literature search, supracondylar femur fracture is not a rare circumstance with morbid obesity. We report a case of closed reduction and internal fixation for a supracondylar femur fracture of a 46-year-old, 168 kg, 172 cm tall [body mass index (BMI) > 55 kg/m2] morbid obese man. The patient was premedicated with diazepam 10 mg orally and was brought to the operating room on a transport stretcher and taken onto conventional operating tables hardly that had been placed side by side. Since the morbidly obese patient has such risk factors as hypertension and Mallampati Score IV and type II diabetes and obstructive sleep apnea (OSA), standard dose spinal anesthesia, including hyperbaric bupivacaine and fentanyl mixture, was decided to be given. As the consequences of proper attention to special status such as easy positioning, suitable anesthesia technique, avoiding complications about airway and haemodynamics, he safely underwent to the closed reduction with singe dose spinal anesthesia.
Clinical Characteristics And Treatment Modalities Of Childhood Hemangiomas
Authors: Çıtak Elvan Çağlar , Oğuz Aynur
Published: June 2023

Hemangiomas are the most common type of congenital anomaly in childhood. Fortunately, most hemangiomas only grow to small size and do not cause problems. However, there is a small subset of hemangiomas that destroy tissue or endanger the infant's life, either because of tumor's size, location or agressive growth. The pathogenesis of hemangiomas is not well understood, but recent findings suggest a unique vascular phenotype with dysregulated vascular homeostasis. This article reviews new information regarding the pathogenesis of these tumors and highlights the more worrisome presentations, including syndromic hemangiomas, that are likely to be problematic. In addition, management strategies and treatment options are discussed.
Current Problems in Surgical Treatment Of Gastroesophagial Reflux Disease
Authors: Güler Mehmet , Başkonuş İlyas , Balık Ahmet , Gökalp Avni
Published: June 2023

In the last decade restoration of lower esophageal sphincter function has become the choice of treatment rather than medical treatment that decrease acid secretion. The relative advantages of minimally invasive antireflux surgery to conventional surgery increase the role of surgery in treatment of gastroesophagial reflux disease. in this report the type of surgery (open vs laparoscopic), the type of fundoplication (complete vs partial), mobilization of the fundus and use of bougie are discussed.
Editör'den
Authors: Balat Ayşe
Published: June 2023

Sevgili Meslektaşlarım,
Dergimizin 2009 yılı 1. sayısında buluşabilmenin mutluluğunu yaşarken, 2009 yılından itibaren yılda 3 sayı (Ocak, Mayıs, Eylül) çıkacağı müjdesiyle hepinizi sevgi ve saygıyla selamlıyorum. Dergimizin kısa sayılabilecek bir sürede bu düzeye gelmesindeki katkılarından dolayı yazarlara, hakemlere, okurlarımıza ve derginin yayına hazırlanması aşamasında emeği geçen bütün öğretim üyelerine, dergi çalışanlarına içtenlikle teşekkür eder, bir sonraki sayıda buluşabilmek umuduyla sevgi ve saygılarımı sunarım.
 
Prof. Dr. Ayşe BALAT
Editör
 
"Okumadan geçen üç günden sonra konuşma tadını kaybeder"
(Çin Atasözü)
Results Of The Winograd Technique In The Treatment Of Ingrowing Toe Nail
Authors: Ertürk Cemil , Karakurum H.Günhan
Published: June 2023

Ingrown toe nails are common in young people. This condition is painfull and may lead to time off work in addition to restricting recreational activities. Treatment ranges from changing foot wear to extensive surgical procedures. In this study, we evaluated the results of the technique described by Winograd in patients with ingrowing toe nail. The study included 28 patients (20 males, 8 females; mean age 25 years; range 14 to 56 years) who were treated with the technique describe by Winograd for ingrown toenails. A total of 31 ingrown nail edges were treated. According to the Heifetz's staging system, 14 patients had stage 2, 17 patients had stage 3 disease. The infected cases were operated on after improvement of inflammation by antibiotic treatment. Recurrences and satisfaction level of the patients were evaluated during a mean follow-up period of 22 months (range 12 to 36 months). Recurrence was seen in two patients (6.4%). 26 patients (92%) were satisfied with the treatment, with relief of their symptoms. Two patients who developed recurrences expressed dissatisfaction with surgery. The Winograd technique is a successfull surgical treatment of stage 2-3 ingrown toenails, with a relatively low recurrence rate and high levels of patient satisfaction.
Fat Mass Lipid Profile And Relations To Bone Mineral Density
Authors: Altındağ Özlem , Soran Neslihan , Sert Cemil
Published: June 2023

Various studies have examined bone mineral density and its relation to fat mass, but arrived at contradictory results. Our study were planned to evaluate the connection between bone mineral density, serum lipid profile and fat mass. Total fat mass and bone mineral density were measured by dual energy x-ray absorptiometry in 29 women. Serum lipid profile was also evaluated by routine biochemical methods. Total fat mass, cholesterol, trigliserid, LDL, VLDL levels were higher and HDL level were lower in patients with t score < -2.5 than in 16 patients with t score > -1.5. Furthermore, cholesterol level was negatively correlated with bone mineral density and positively correlated with fat mass and percent fat. According to our results, serum total cholesterol level was higher in patients with higher total fat mass and bone mineral density was lover in patients with hypercholesterolemia.
The Effects Of Bipolar And Monopolar Resectoscope On Hemodynamic And Plasma Electrolytes In Transurethral Resection Procedures
Authors: Pirbudak Çöçelli Lütfiye , Erturhan Sakıp , Özkan Tanrıverdi Gülşen , Şen Haluk , Erbağcı Ahmet , Öner Ünsal
Published: June 2023

In our study, we compared the effects of monopolar and bipolar resectoscope use on hemodynamics, serum electrolytes, and length of hospital stay of patients who is undergoing TUR-P with spinal anesthesia. After approval of the Faculty Ethical Committee and the written consent of the patients, 60 patients are randomly allocated into two groups that is planned to perform TUR-P with bipolar resectoscope (Group B)(n=30) group and monopolar resectoscope (Group M)(n=30), respectively. Spinal anesthesia had been performed to all patients. Blood pressure, heart rate and respiratory rate were monitorized with five minutes periods during the operation. Serum Na+, K+, Cl-, Hb ve Hct values measured before the operation, at 30. minute of the operation, 1., 24. h after the operation. Urethral catheterization time and length of hospital stay had been recorded. In Group M , blood pressure of the patients at 25th and 30th minutes had been decreased significantly comparison to the control values (p<0.05). Serum Na+ values at intraoperative 30th min, postoperative 1st, 24th h of the patients in group M had been reduced significantly in comparison with the preoperative values; serum K+, Hb, Hct values at the postoperative 1st, 24th hours reduced significantly in comparison with the preoperative values (p<0.05). However, none of the patients in Group M had TUR syndrome. We observed that, in bipolar TURP method duration of the operation and length of hospital stay were found significantly short, as well as hemodynamic stability and electrolyte balance were found better than in monopolar TURP method.
Editör'den
Authors: Balat Ayşe
Published: June 2023

Sevgili Meslektaşlarım,
Geçen sayılarda, "Gaziantep Tıp Dergisi"ni yılda 3 sayıya çıkarabilmeyi hedeflediğimizi belirtmiştim. Bunu gerçekleştirmenin mutluluğuyla, hepinizi sevgi ve saygıyla selamlıyorum. Dergimiz TÜBİTAK-Türk Tıp Dizini ve uluslar arası EBSCO veri tabanınca takip edilmektedir. Sokrates "Bütün bildiğim, bir şey bilmediğimdir" ve "Bir şeyi gerçekten bilmek, onu anlatmakla olur" diyerek kendini geliştirme ve devamlı sorgulamanın mükemmele ulaşmada, paylaşımda ne kadar önemli olduğunu özetlemiştir. Dergimiz aracılığıyla bu sorgulama ve bilgi paylaşımına-katkıda bulunabilmek bizleri mutlu edecektir. Değerli çalışmalarıyla dergimizi destekleyen bütün araştırıcılara ve yayına hazırlanmasında emeği geçenlere teşekkür eder, bir sonraki sayıda buluşabilmek umuduyla sevgi ve saygılarımı sunarım.
 
Prof. Dr. Ayşe BALAT
Editör
 
"Bilgi, sınırı olmayan bir denizdir. Bilgi dileyense denizlere dalan bir dalgıçtır."
Mevlana
 
"Önce doğruyu bilmek gerekir, doğru bilinirse yanlış da bilinir. Ama önce yanlış bilinirse doğruya ulaşılamaz."
Farabi