bluuebunny/crossref_metadata_2025 huggingface dataset:
The effect of renal function change on renal cell carcinoma patients with tumor thrombus after nephrectomy and thrombectomy: a large Chinese center experience
Authors: Liu Zhuo , Tang Shiying , Tian Xiaojun , Zhang Hongxian , Wang Guoliang , Zhang Shudong , Ma Lulin
Published: January 2020

Background

To explore the influencing factors of perioperative renal function change and their relationship with prognosis on renal cell carcinoma (RCC) patients with tumor thrombus after nephrectomy and thrombectomy.

Methods

The clinical and pathological data of 135 patients with RCC and tumor thrombus, who underwent nephrectomy and thrombectomy at Peking University Third Hospital from May 2015 to July 2018, was retrospectively analyzed. Absolute change in estimated glomerular filtration rate (eGFR) (ACE) and percent change in eGFR (PCE) were calculated by preoperative and postoperative renal function. Linear regression analysis was used to explore the influencing factors of ACE and PCE, and logistic regression analysis was used to explore the influencing factors of worse postoperative renal function [eGFR≤60 mL/(min × 1.73 m^2)]. Cancer-specific survival (CSS) was estimated by Kaplan-Meier method and multivariate Cox regression, which were used to explore the effect of ACE and PCE on prognosis.

Results

Of all the 135 patients, 101 patients (74.8%) were male and 34 patients (25.2%) were female. The mean preoperative eGFR was 73.9 ± 21.8 mL/(min × 1.73 m^2) and postoperative eGFR was 69.5 ± 25.2 mL/(min × 1.73 m^2). In multivariate linear regression analysis, preoperative eGFR (P < 0.001) and pathological type (P = 0.038) were significant predictive factors of ACE. In aspect of PCE, preoperative eGFR (P < 0.001) and pathological type (P = 0.002) were significant predictors. In multivariate logistic regression analysis, preoperative eGFR (P = 0.016) was the only risk factor of predicting worse postoperative renal function. During follow-up, 22 patients (16.3%) were dead due to RCC. According to ROC analysis, the cut off value of ACE and PCE was 13.9 and 0.16, respectively. ACE> 13.9 and PCE > 0.16 indicated worse CSS (P = 0.006 and P = 0.047, respectively). However, in multivariate Cox regression analysis of several related factors, perinephric tissues invasion (P = 0.001), sarcomatoid differentiation (P = 0.001) and ACE> 13.9 (P = 0.002) were significant prognostic factors for CSS. PCE > 0.16 seemed to be not (P = 0.055).

Conclusion

We explored several clinicopathological risk factors of predicting renal function change and their relationship with prognosis of RCC patients with tumor thrombus after nephrectomy and thrombectomy. The renal function change, which was associated with preoperative eGFR and pathological type, was prognostic risk factor for CSS and ACE> 13.9 indicated the worse prognosis.
Changes in the number of suicide re-attempts in a French region since the inception of VigilanS, a regionwide program combining brief contact interventions (BCI)
Authors: Fossi Djembi Larissa , Vaiva Guillaume , Debien Christophe , Duhem Stéphane , Demarty Anne-Laure , Koudou Yves-Akoli , Messiah Antoine
Published: January 2020

Background

Brief Contact Interventions (BCIs) after a suicide attempt (SA) are an important element of prevention against SA and suicide. They are easier to generalize to an entire population than other forms of intervention. VigilanS generalizes to a whole French region a BCI combining resource cards, telephone calls and mailings, according to a predefined algorithm. It was implemented gradually in the Nord-Pas-de-Calais (NPC), France, between 2015 and 2018. Here, we evaluate the effectiveness of VigilanS, in terms of SA reduction, using annual data collected by participating centers. Hypothesis tested: the higher the VigilanS implementation in a center (measured by penetrance), the greater the decrease in the number of SA observed in this center.

Methods

The study period was from 2014 to 2018, across all of NPC centers. We performed a series of linear regressions, each center representing a statistical unit. The outcome was the change in the number of SA, relative to the initial number, and the predictive variable was VigilanS’ penetrance: number of patients included in VigilanS over the total number of SA. Search for influential points (points beyond threshold values of 3 influence criteria) and weighted least squares estimations were performed.

Results

Twenty-one centers were running VigilanS in 2018, with an average penetrance of 32%. A significant relationship was identified, showing a sharp decrease in SA as a function of penetrance (slope = − 1.13; p = 3*10− 5). The model suggested that a 25% of penetrance would yield a SA decrease of 41%.

Conclusion

VigilanS has the potential to reduce SA. Subgroup analyzes are needed to further evaluate its effectiveness. Subgroup analyses remain to be done, in order to evaluate the specific variations of SA by group.
Inequalities and factors associated with adherence to diabetes self-care practices amongst patients at two public hospitals in Gauteng, South Africa
Authors: Mutyambizi Chipo , Pavlova Milena , Hongoro Charles , Groot Wim
Published: January 2020

Background

Self- management is vital to the control of diabetes. This study aims to assess the diabetes self-care behaviours of patients attending two tertiary hospitals in Gauteng, South Africa. The study also seeks to estimate the inequalities in adherence to diabetes self-care practices and associated factors.

Methods

A unique health-facilities based cross-sectional survey was conducted amongst diabetes patients in 2017. Our study sample included 396 people living with diabetes. Face-to-face interviews were conducted using a structured questionnaire. Diabetes self-management practices considered in this study are dietary diversity, medication adherence, physical activity, self-monitoring of blood-glucose, avoiding smoking and limited alcohol consumption. Concentration indices (CIs) were used to estimate inequalities in adherence to diabetes self-care practices. Multiple logistic regressions were fitted to determine factors associated with diabetes self-care practices.

Results

Approximately 99% of the sample did not consume alcohol or consumed alcohol moderately, 92% adhered to self-monitoring of blood-glucose, 85% did not smoke tobacco, 67% adhered to their medication, 62% had a diverse diet and 9% adhered to physical activity. Self-care practices of dietary diversity (CI = 0.1512) and exercise (CI = 0.1067) were all concentrated amongst patients with higher socio-economic status as indicated by the positive CIs, whilst not smoking (CI = − 0.0994) was concentrated amongst those of lower socio-economic status as indicated by the negative CI. Dietary diversity was associated with being female, being retired and higher wealth index. Medication adherence was found to be associated with older age groups. Physical activity was found to be associated with tertiary education, being a student and those within higher wealth index. Self-monitoring of blood glucose was associated with being married. Not smoking was associated with being female and being retired.

Conclusion

Adherence to exercising, dietary diversity and medication was found to be sub-optimal. Dietary diversity and exercise were more prevalent among patients with higher socio-economic status. Our findings suggest that efforts to improve self- management should focus on addressing socio-economic inequalities. It is critical to develop strategies that help those within low-socio-economic groups to adopt healthier diabetes self-care practices.
What factors contribute to the self-reported oral health status of Arab adolescents? An assessment using a validated Arabic-WHO tool for child oral health (A-OHAT)
Authors: Bokhari Ahmed M. , Quadri Mir Faeq Ali
Published: January 2020

Background

The current study was performed; to validate the Arabic version of WHO child oral health assessment tool (A-OHAT), to assess the oral health status of Arab school children and finally to identify the important risk factors associated with the poor teeth and gum conditions of school children.

Methods

A cross-sectional study with two-staged simple random sampling technique was implemented. A-OHAT, a self-assessment tool was subjected to psychometric analyses with the respondents being high school children. The Cronbach’s alpha and the Intra class correlation values were computed. Paired t-test was performed to identify the differences between the readings after repeated administration, followed by the analysis for convergent validity. This tested Arabic-WHO Child-OHAT was administered to collect the data. Univariate, bivariate and logistic regression analyses were performed to report on the potential risk factors associated with poor teeth and poor gum conditions of school children.

Results

Psychometric analyses revealed that the Arabic Child Oral Health Assessment Tool (A-OHAT) was reliable and valid. A total of 478 (N) high school children were subjected to the tested tool, of which 66.5% were male and 33.5% were female with a mean age of 16.28 + 1.04 years. 80.3% of school children had poor teeth condition and 36.2% of school children had often experienced toothache. Children had 1.5 times higher odds of having poor teeth condition if they had increased frequency of sweet and candy consumption. It was also seen that increased frequency of sweets and candy consumption by school children had put them at nearly 20% higher risk of having poor gum condition. Finally, children with the habit of using toothbrush had nearly 50% lower chance of having poor gum condition in contrast to the school children who do not use toothbrush.

Conclusion

To conclude, the study provides a reliable and valid tool to assess the oral health status of Arab adolescents. Improper oral hygiene habits and diet were identified as the plausible risk factors for poor teeth and gum condition.
Association of insulin resistance, from mid-life to late-life, with aortic stiffness in late-life: the Atherosclerosis Risk in Communities Study
Authors: Poon Anna K. , Meyer Michelle L. , Tanaka Hirofumi , Selvin Elizabeth , Pankow James , Zeng Donglin , Loehr Laura , Knowles Joshua W. , Rosamond Wayne , Heiss Gerardo
Published: January 2020

Background

Insulin resistance may contribute to aortic stiffening that leads to end-organ damage. We examined the cross-sectional association and prospective association of insulin resistance and aortic stiffness in older adults without diabetes.

Methods

We analyzed 2571 men and women at Visit 5 (in 2011–2013), and 2350 men and women at repeat examinations from baseline at Visit 1 (in 1987–1989) to Visit 5 (in 2011–2013). Linear regression was used to estimate the difference in aortic stiffness per standard unit of HOMA-IR, TG/HDL-C, and TyG at Visit 5. Linear mixed effects were used to assess if high, as opposed to non-high, aortic stiffness (> 75th percentile) was preceded by a faster annual rate of change in log-HOMA-IR, log-TG/HDL-C, and log-TyG from Visit 1 to Visit 5.

Results

The mean age of participants was 75 years, 37% (n = 957) were men, and 17% (n = 433) were African American. At Visit 5, higher HOMA-IR, higher TG/HDL-C, and higher TyG were associated with higher aortic stiffness (16 cm/s per SD (95% CI 6, 27), 29 cm/s per SD (95% CI 18, 40), and 32 cm/s per SD (95% CI 22, 42), respectively). From Visit 1 to Visit 5, high aortic stiffness, compared to non-high aortic stiffness, was not preceded by a faster annual rate of change in log-HOMA-IR from baseline to 9 years (0.030 (95% CI 0.024, 0.035) vs. 0.025 (95% CI 0.021, 0.028); p = 0.15) or 9 years onward (0.011 (95% CI 0.007, 0.015) vs. 0.011 (95% CI 0.009, 0.013); p = 0.31); in log-TG/HDL-C from baseline to 9 years (0.019 (95% CI 0.015, 0.024) vs. 0.024 (95% CI 0.022, 0.026); p = 0.06) or 9 years onward (− 0.007 (95% CI − 0.010, − 0.005) vs. − 0.009 (95% CI − 0.010, − 0.007); p = 0.08); or in log-TyG from baseline to 9 years (0.002 (95% CI 0.002, 0.003) vs. 0.003 (95% CI 0.003, 0.003); p = 0.03) or 9 years onward (0 (95% CI 0, 0) vs. 0 (95% CI 0, 0); p = 0.08).

Conclusions

Among older adults without diabetes, insulin resistance was associated with aortic stiffness, but the putative role of insulin resistance in aortic stiffness over the life course requires further study.
Perceived poverty and health, and their roles in the poverty-health vicious cycle: a qualitative study of major stakeholders in the healthcare setting in Hong Kong
Authors: Chung Gary Ka-Ki , Dong Dong , Wong Samuel Yeung-Shan , Wong Hung , Chung Roger Yat-Nork
Published: January 2020

Background

Poverty and ill-health are closely inter-related. Existing studies on the poverty-health vicious cycle focus mainly on less developed countries, where the identified mechanisms linking between poverty and ill-health may not fit the situations in developed Asian regions. This study aims to qualitatively explore the perceived mechanisms and drivers of the poverty-health vicious cycle among major stakeholders in the healthcare setting in Hong Kong.

Methods

Data were collected via focus group interviews with social workers (n = 8), chronically ill patients (n = 8), older adults (n = 6), primary care doctors (n = 7) and informal caregivers (n = 10). The transcribed data were then closely read to capture key themes using thematic analyses informed by social constructivism.

Results

In this highly developed Asian setting with income inequality among the greatest in the world, the poverty-health vicious cycle operates. Material and social constraints, as a result of unequal power and opportunities, appear to play a pivotal role in creating uneven distribution of social determinants of health. The subsequent healthcare access also varies across the social ladder under the dual-track healthcare system in Hong Kong. As health deteriorates, financial hardship is often resulted in the absence of sufficient and coordinated healthcare, welfare and labour policy interventions. In addition to the mechanisms, policy drivers of the cycle were also discussed based on the respondents’ perceived understanding of the nature of poverty and its operationalization in public policies, as well as of the digressive conceptions of disease among different stakeholders.

Conclusions

The poverty-health vicious cycle has remained a great challenge in Hong Kong despite its economic prosperity. To break the cycle, potential policy directions include the adoption of proportionate universalism, social integration and the strengthening of medical-social collaboration.
Early metabolic response of breast cancer to neoadjuvant endocrine therapy: comparison to morphological and pathological response
Authors: Boughdad Sarah , Champion Laurence , Becette Veronique , Cherel Pascal , Fourme Emmanuelle , Lemonnier Jerome , Lerebours Florence , Alberini Jean-Louis
Published: January 2020

Background

Neoadjuvant endocrine therapy (NET) has shown efficacy in terms of clinical response and surgical outcome in postmenopausal patients with estrogen receptor-positive / HER2-negative breast cancer (ER+/HER2- BC) but monitoring of tumor response is challenging. The aim of the present study was to investigate the value of an early metabolic response compared to morphological and pathological responses in this population.

Methods

This was an ancillary study of CARMINA 02, a phase II clinical trial evaluating side-by-side the efficacy of 4 to 6 months of anastrozole or fulvestrant. Positron Emission Tomography/Computed Tomography using 2-deoxy-2-[18F]fluoro-D-glucose (FDG-PET/CT) scans were performed at baseline (M0), early after 1 month of treatment (M1) and pre-operatively in 11 patients (74.2 yo ± 3.6). Patients were classified as early “metabolic responders” (mR) when the decrease of SUVmax was higher than 40%, and “metabolic non-responders” (mNR) otherwise. Early metabolic response was compared to morphological response (palpation, US and MRI), variation of Ki-67 index, pathological response according to the Sataloff classification and also to Preoperative Endocrine Prognostic Index (PEPI) score. It was also correlated with overall survival (OS) and recurrence-free survival (RFS).

Results

Tumor size measured on US and on MRI was smaller in mR than mNR, with the highest statistically significant difference at M1 (p = 0.01 and 7.1 × 10− 5, respectively). No statistically significant difference in the variation of tumor size between M0 and M1 assessed on US or MRI was observed between mR and mNR. mR had a better clinical response: no progressive disease in mR vs 2 in mNR and 2 partial response in mR vs 1 partial response in mNR. One patient with a pre-operative complete metabolic response had the best pathological response. Pathological response did not show any statistically significant difference between mR and mNR. mR had better OS and RFS (Kaplan-Meier p = 0.08 and 0.06, respectively). All cancer-related events occurred in mNR: 3 patients died, 2 of them from progressive disease.

Conclusions

FDG-PET/CT imaging could become a “surrogate marker” to monitor tumor response, especially as NET is a valuable treatment option in postmenopausal women with ER+/HER2- BC.
The tyranny of the head office? Revisiting corporate headquarters’ (CHQs) role in MNE subsidiary initiatives
Authors: Verbeke Alain , Yuan Wenlong
Published: January 2020

What roles should corporate headquarters (CHQs) of multinational enterprises (MNEs) play in foreign subsidiary initiatives? Rather than viewing the MNE’s CHQ as a single, internally homogenous unit, we call for examining the diversity of individual decision-makers who can be driven by a variety of motivations and have different abilities. Motivations and abilities together determine whether or not corporate executives will choose to intervene in subsidiary initiatives and the effectiveness of such intervention. If dysfunctional, the “tyranny of the head office” materializes. We apply the Coleman-boat concept to show how contextual analyses at the MNE level and the proposed analyses of individual decision-makers need to be combined when exploring the underlying micro-foundational mechanisms of decisions.
Impact of diffusion weighted magnetic resonance imaging in diagnosis of cervical cancer
Authors: Abd elsalam Sahar Mahmoud , Mokhtar Omnia , Adel Lamia , Hassan Reda , Ibraheim Manal , Kamal Amro
Published: January 2020

Background

Cervical cancer is a widespread cancer among women worldwide. In this study, we evaluated the role of diffusion weighted magnetic resonance imaging (DWI-MRI) in diagnosis of cervical carcinoma with pathological diagnosis taken as the reference. The study included 70 patients in whom cancer cervix had been suspected clinically or by transvaginal U/S and confirmed by biopsy. The control group consisted of 40 patients with a normal cervix who performed MRI for other pelvic disorders. Pelvic MR with DWI and dynamic contrast enhanced MRI (DCE-MR) were done for all patients.

Results

Both DW-MRI and DCE-MRI revealed the same sensitivity, specificity, PPV, and accuracy; 100%, 50%, 97%, and 97%, respectively. The mean ADC value for malignant lesions was (0.82 × 10−3 ± 0.1 SD mm2/s). While the mean ADC value in the control group is (1.56 × 10–3 mm2/s). ADC value of (1.07 × 10−3 mm2/s) is a cut-off between normal cervical tissue& malignant cervical lesion with a sensitivity 97% and specificity 95.5%

Conclusion

Each of the (DW-MRI) and (DCE-MRI) sequences when added to the non-contrast MRI sequences in the estimation of cancer cervix had elicited the same sensitivity, specificity, and accuracy. DW–MRI was significantly beneficial in terms of diagnostic performance. For patients who cannot receive contrast medium, dynamic contrast-enhanced imaging can be replaced by DWI. The ADC value in case of cervical cancer was significantly lower than in the non-affected cervical tissue.
The asymmetry and cooperativity of tandem glycine riboswitch aptamers
Authors: Torgerson Chad D. , Hiller David A. , Strobel Scott A.
Published: January 2020

Glycine riboswitches utilize both single- and tandem-aptamer architectures. In the tandem system, the relative contribution of each aptamer toward gene regulation is not well understood. To dissect these contributions, the effects of 684 single mutants of a tandem ON switch from Bacillus subtilis were characterized for the wild-type construct and binding site mutations that selectively restrict ligand binding to either the first or second aptamer. Despite the structural symmetry of tandem aptamers, the response to these mutations was frequently asymmetrical. Mutations in the first aptamer often significantly weakened the K1/2, while several mutations in the second aptamer improved the amplitude. These results demonstrate that this ON switch favors ligand binding to the first aptamer. This is in contrast to the tandem OFF switch variant from Vibrio cholerae, which was previously shown to have preferential binding to its second aptamer. A bioinformatic analysis of tandem glycine riboswitches revealed that the two binding pockets are differentially conserved between ON and OFF switches. Altogether, this indicates that tandem ON switch variants preferentially utilize binding to the first aptamer to promote helical switching, while OFF switch variants favor binding to the second aptamer. The data set also revealed a cooperative glycine response when both binding pockets were maximally stabilized with three GC base pairs. This indicates a cooperative response may sometimes be obfuscated by a difference in the affinities of the two aptamers. This conditional cooperativity provides an additional layer of tunability to tandem glycine riboswitches that adds to their versatility as genetic switches.
Museus de arte universitários: vocações, especificidades e potencialidades
Authors: De Albuquerque Fernanda Carvalho , Frozza Marília De Oliveira
Published: January 2020

Este artigo parte do levantamento sobre as definições, funções e origens dos museus de arte universitários para estabelecer uma reflexão sobre os papeis e o lugar dessas instituições na universidade. A vocação dos museus para atuar enquanto plataformas de ensino, pesquisa e extensão é o ponto de partida para reconhecer particularidades e indagar potencialidades.
Torreão – das imagens inesquecidas
Authors: Luersen Paula
Published: January 2020

O Torreão é um acontecimento que continua a ressoar. Proposto por Elida Tessler e Jailton Moreira, o espaço marcou o contexto da arte brasileira nos anos 90/ 2.000. O artigo situa, entre relatos e ficções, as práticas que movimentaram o cotidiano da casa e a trajetória dos alunos no exercício de produção e reflexão em arte contemporânea.
Vitamin D and obesity in adults: a pathophysiological and clinical update
Authors: Feghaly Julien , Johnson Paul , Kalhan Atul
Published: January 2020

Vitamin D deficiency has become an increasing focus of clinical interest, especially in understanding its associations with obesity in adults. The pathological associations linking the two appear to demonstrate complex cellular inflammatory, hormonal and genetic pathways. Enhanced understanding at both microcellular and clinical levels will help clarify the role of obesity in the development of vitamin D deficiency.
Trace elements in sheep — are they really a cure all?
Authors: Hinde Davinia
Published: January 2020

Trace elements are an important factor on many sheep farms and a good way to engage clients when veterinary surgeons can become involved with an aspect of on-farm nutrition. This article outlines the major trace elements required by sheep, i.e. copper, cobalt, iodine and selenium, and discusses ways in which veterinary surgeons can become engaged with farmers around trace elements such as mineral audits and pre-mating blood samples. The appropriate laboratory tests for each trace element are discussed as well as the options for treatment and prevention of deficiencies.
Embracing the Cascade part 3: clinical decision making in equine asthma
Authors: Bailey James , Bowen Mark
Published: January 2020

Equine asthma is the current terminology that covers chronic non-infectious lower airway disorders in the horse. Mild and moderate equine asthma reflect the syndrome previously referred to as inflammatory airway disease, while severe asthma reflects both recurrent airway obstruction and summer pasture-associated obstructive airway disease. Corticosteroids are the most important therapeutic agents for the management of horses with all severities of equine asthma. Prednisolone and dexamethasone products are authorised for use in horses and can be used for the management of asthma. Inhaled corticosteroids have the potential advantages of reduced systemic effects and reduced detection times in competition animals. ‘Special’ (extemporaneous) formulations of oral dexamethasone may be valuable in horses with severe asthma. A range of bronchodilator therapies can be used for the management of severe asthma; although the clinical efficacy of systemic bronchodilators still lacks a robust evidence base, they may have a particular role in ‘rescue-therapy’ and in acute exacerbations. The evidence for the use of mucolytic agents is limited and excessive mucus production should resolve with improvements in airway inflammation. Inhaled saline and inhaled acetylcysteine may provide useful improvements in mucus secretion without any effects on competition horses. Mast cell stabilisers may have a role in the management of mild equine asthma, although they have a limited evidence base for their use. The use of the prescribing cascade provides access to a range of medications that are useful in the management of equine asthma.
A complementaridade entre filosofia e teologia no pensamento de Tomás de Aquino
Authors: De Souza Melo Marco César
Published: January 2020

O escopo do presente trabalho é apresentar um estudo sobre os conceitos de filosofia e teologia no pensamento do filósofo medieval Tomás de Aquino. Analisaremos os referidos conceitos com base nos escritos do autor nas obras: Suma Contra os Gentios e Suma Teológica, considerando exclusivamente os capítulos que tratam do objeto de estudo. Nossa metodologia consistiu na leitura exegética dos textos procurando verificar o sentido dos conceitos concernentes ao objeto de pesquisa bem como a tessitura que se estabelece entre os mesmos. Procuramos averiguar a validade da hipótese de que a teologia segue necessariamente do pensar filosófico na escala do conhecimento em Tomás de Aquino e, além disso, essa sequência nos revela uma relação de complementaridade entre ambas.
Francisco Suárez e a substância
Authors: De Oliveira José Edelberto Araújo
Published: January 2020

Expõe elementos da fundamentação do conceito de substância contida no desenvolvido do pensamento de Suárez
Tese da compatibilidade na teoria do intelecto de Tomás de Aquino
Authors: Borges Lucas Nogueira
Published: January 2020

A proposta deste artigo consiste em demonstrar que a teoria do intelecto em Tomás de Aquino exige uma relação de compatibilidade entre o objeto externo (extra animam) e o intelecto humano. O intelecto, princípio da ação intelectiva, não é compatível com o objeto externo, porque é imaterial. Entretanto, sua operação é compatível com a coisa material.  A tese do modelo de identidade formal na teoria da intencionalidade de Tomás de Aquino elucida que o intelecto pode se referir a objetos no mundo porque há entre ele e seu objeto um princípio de identidade entre a forma existente na coisa e a forma existente no intelecto humano. Partindo dessa tese já consagrada, pretende-se mostrar que certas afirmações de Aristóteles interpretadas por Tomás explicam por que o intelecto humano é capaz e está, na maioria dos casos, em condições de apreender objetos materiais. Assim nesse trabalho são discutidas quais as propriedades do intelecto humano segundo Tomás, enquanto potência da alma e, por fim, sustenta-se a tese de que a exigência do objeto para as operações do intelecto é um princípio de compatibilidade.
Esferas públicas em conflito: contribuições de Nancy Fraser ao conceito de esfera pública
Authors: Marra Laísa
Published: January 2020

O artigo objetiva apresentar uma síntese das contribuições da pesquisadora feminista Nancy Fraser ao conceito de esfera pública, tendo como eixo da discussão as críticas feitas pela autora a quatro pressupostos habermasianos de tal conceito. Para tanto, apresentam-se brevemente as formulações de JürgenHabermas, para depois problematizá-las conforme Fraser. Ademais, concordando-se com Michael Warner, a defesa que faz Fraser da ideia de "contra-públicos subalternos" é questionada por simplificar a noção de subalternidade. Por fim, avalia-se a utilidade das questões levantadas por Fraser para se pensar os problemas de desigualdades e liberalismo enfrentados pelas democracias existentes. Palavras-chave: Esfera pública. Nancy Fraser. Jürgen Habermas. Crítica feminista.
Measuring the refractive index of optical adhesives at cryogenic temperatures
Authors: Hou Xintong , Yao Ni , You Lixing , Li Hao , Fang Wei , Zhang Weijun , Wang Zhen , Tong Limin , Xie Xiaoming
Published: January 2020

The development of photonic quantum information technologies requires research on the properties of optical adhesives at cryogenic temperatures. In the process of developing microfiber (MF)-coupled superconducting nanowire single-photon detectors (SNSPDs), we invented a cryogenic-temperature refractive index (RI) measurement method based on a kind of MF device. The device was put into the cryostat to observe the variance of MF transmittance with temperature. Then an RI–temperature relationship was established through the correspondence between the confinement conditions of MFs of various diameters in an optical adhesive–

M
g
F

2

environment and transmittance–temperature curves. Using this method, we analyzed the thermal-optical properties of a commercial fluorinated acrylic optical adhesive and obtained the RI values of the adhesive at various temperatures. The results were successfully applied in the development of broadband and high-efficiency MF-coupled SNSPDs.
Enunciación, imagen social y gramaticalización: una aproximación al análisis de las construcciones todo hay que decirlo y por qué no decirlo
Authors: Brenes Peña María Ester
Published: January 2020

Este trabajo aborda el análisis pragmalingüístico de dos construcciones que han comenzado el proceso hacia su fijación como operadores discursivos. Nos referimos, en concreto, a las expresiones metalingüísticas todo hay que decirlo y por qué no decirlo. Ambas coinciden en su construcción de base (estructuras oracionales formadas a partir del verbo decir), en desarrollar valores enunciativos relacionados con el control que posee el hablante en la formulación de su discurso y en su vinculación con las operaciones de gestión de la imagen social. El estudio realizado aspira a identificar las funciones discursivas que han comenzado a actualizar en el plano macroestructural, a detallar el grado de fijación alcanzado por cada una de ellas y, en definitiva, a determinar si ambas construcciones han alcanzado o no el estatus de operador del discurso. Se trata, pues, de un trabajo que se centra en el aspecto productivo del sistema, dimensión poco abordada hasta el momento.
Coordinación entre oraciones y operadores de modalidad: de la “micro” a la (macro)sintaxis
Authors: López Martín José Manuel
Published: January 2020

A través de este estudio intentaremos mostrar que existen determinados operadores, más concretamente modales, que pueden funcionar y comportarse en el discurso de una manera no descrita en anteriores trabajos. Más concretamente nos referimos a que estas partículas que suelen moverse dentro de un territorio extra-oracional pueden, en ocasiones, ocupar el hueco sintáctico de una oración, y, dejando a un lado su función marginal, aparecer relacionadas con otra construcción oracional a través de una conjunción coordinada (y/pero). De esta manera, entre el operador y la construcción se llega a establecer cierta equivalencia funcional. Por otro lado, algunas de estas construcciones terminan gramaticalizándose mediante el uso, dando lugar a nuevos operadores que poseen matices discursivos más complejos.
Di (tú) que como marcador del discurso
Authors: Grande Alija Francisco Javier
Published: January 2020

Este trabajo se centra en el estudio del comportamiento de un marcador del discurso que ha recibido poca atención, pese a que está bien representado en el uso del español coloquial: di (tú) que. El objetivo principal de este estudio es llevar a cabo una descripción de las propiedades formales, semánticas y discursivas de di (tú) que a partir de un corpus de ejemplos de textos con rasgos coloquiales. Nuestro análisis identifica tres valores básicos: intensificación, inductor de ironía e hipótesis, así como diferentes grados de gramaticalización en el proceso que va de una construcción verbal con un verbo en imperativo a un marcador del discurso.
Por (lo) tanto en “contextos reducidos” (I): análisis cuantitativo y formal
Authors: De la Fuente García Mario , Iglesias Bango Manuel , Maquieira Rodríguez Marina
Published: January 2020

En este trabajo se tratan ciertos contextos en los que el marcador consecutivo por (lo) tanto pone en relación elementos no oracionales. De estos casos, a los que proponemos llamar “contextos reducidos”, interesan en esta primera entrega los aspectos cuantitativos y formales. Se intentará determinar, pues, si los ejemplos de esos contextos son relevantes estadísticamente, y a qué tipos de sintagmas afecta más. Además, se tratará especialmente la inestabilidad que se observa, en el corpus utilizado, respecto a la presencia/ausencia de pausas enmarcando la locución, y se comprobará si esa característica entonativa afecta también a otros marcadores consecutivos como por consiguiente y en consecuencia. Este estudio tendrá continuidad en una segunda entrega, en la que analizaremos los aspectos cualitativos.
Mengembangkan Kreativitas Anak Melalui Bermain
Authors: Putro Khamim Zarkasih
Published: January 2020

Sebagai orang tua atau pendidik perlu mengembangkan serta memberikan berbagai stimulasi positif agar anak dapat menjadi kreatif. Kreativitas anak dapat dilihat dari cara bermain. Melalui bermain anak belajar mengenal diri dan lingkungannya, karena dengan bermain anak belajar. Ada berbagai macam jenis permainan yang dapat digunakan dalam mengembangkan kreativitas anak.Bermain memberikan kesenangan, kebahagian bagi anak dan memenuhi kebutuhan mereka. Jenis kegiatan bermain mempunyai sumbangan positif baik terhadap penyesuaian sosial maupun penyesuaian diri anak dan perkembangan emosi, kepribadian maupun perkembangan kognisinya.Bermain merupakan pengalaman belajar yang sangat berguna untuk anak dan memiliki beberapa manfaat bagi perkembangan anak yaitu perkembangan fisik, sosial emosinal, kognitif atau intelektual serta bahasa. Selain itu manfaat yang didapatkan dari kegiatan bermain adalah mengembangkan kreativitas.Bermain dalam bentuk apapun baik aktif maupun pasif baik dengan alat maupun tanpa alat dapat menunjang kreativitas anak. Dengan bermain anak dapat menilai dirinya sendiri, kelebihan dan kekurangannya sehingga dapat membantu pembentukan konsep diri yang positif yaitu mempunyai rasa percaya diri. Anak akan belajar cara bersikap dan bertingkah laku agar dapat bekerja sama dengan orang lain, jujur, murah hati dan sebagainya. Peran orang tua dan guru memfasilitasi anak dengan cara menyediakan sarana bermain yang aman, nyaman dan tepat sesuai dengan bakat, minat, perkembangan dan kebutuhan anak.
Komunikasi Kenusantaraan (Studi Komunikasi Nusantara Perspektif Integrasi Interkoneksi)
Authors: Mahfud Mokhamad
Published: January 2020

The term "think globally and act locally" has begun to surface since the eighties, but until now, a quarter century later, there was also a surefire formula go see about it. Human experience feel things that otherwise like sara (suku, agama dan ras)  events that befall the nation, instead of peace, mutual trust, peaceful coexistence, at-ta'ayus as-silmi, tolerance, tasamuh among fellow human beings and between groups, but rather violence, violence , prejudice (prejudice), az- su'u zan  religion, ethnicity, class, race, interests, both at the local, regional, national and even international (global). As if all want to reverse the adage "think locally and act only", without having coupled "think globally". In the associate, connect and communicate with other groups and do not feel the need to consider the governance rules, laws, agreements and international relations.Each ethnic group, religion, class, culture wants to maintain, even cult, sect or school of thought wanted to strengthen and reinforce certain local religious identity, cultural identity, ethnic identity, political identity as felt in the shadow of the threat of domination and cultural hegemony, certain foreign cultures or civilizations.Pressure of social psychology in the real and the imagined then cause unfair treatment (injustice), discriminatory (political behavior discrimination of race, ethnicity, religion and origin) and subordinate (humble and do not consider important the presence of another person or group), here as if there is no problem indeed, in maintaining the identity and group identity, but the ripples that appear in events locally, regionally, nationally and internationally to prove there is indeed a problem in the social order of the world.This paper offers a model of communication between fellow men's race (human), which integrates and connectedness with nature and God (spirituality), in the context of Communication Studies allows develop integration-interconnection study Communications, for example, the model trialektika between Islamic, and Indonesian-ness can Modernity in trialektika developed to initiate some sort of communication, namely (Islamic [Komunikasi Islam(i)/ hadarah an-nas/Religion/‘irfani], Indonesianness (Komunikasi Indonesia/ Nusantara/ hadarah al-falsafah /Philosophy/ burhani), and Modernity [Modern/Western Communications]/ hadarah al-‘ilm/Science/bayani), researcher asumtion that Modern Communications refers to Western Communications.Komunikasi Nusantara is a science communication in digging up the basic values of the indegenous values or the values of local wisdom Indonesia (Nusantara Philosophy), then associate with theories derived from Komunikasi Islam(i)/Komunikasi Profetik and Modern/ Western Communications.
Nilai-nilai Ajaran Islam Tentang Perdamaian (Kajian antara Teori dan Praktek)
Authors: Hidayat Nur
Published: January 2020

Secara teori setiap ajaran agama mengajarkan kepada umatnya untuk hidup rukun dan  berdamai. Disamping itu juga mengajarkan saling toleransi dan menghargai kepada perbedaan pendapat dan paham. Sebaliknya, tidak semua ajaran agama mengajarkan pada umatnya melakukan perbuatan kekerasan atau anarkis terhadap umat lainnya atau golongan lain. Tapi secara praktek di lapangan masih sering terjadi penyerangan saling mencela antara satu paham dengan paham yang lainnya bahkan terhadap agama yang berbeda. Dalam artikel ini penulis ingin  menyampaikan tentang missi Islam yaitu suatu agama yang Rahmatan Lil`alamiin, disini agama mengajarkan kepada umatnya untuk hidup saling mencintai antar sesama, menegakkan perdamaian dan saling toleransi antar sesama manusia tanpa membedakan agama dan paham, akan tetapi realitas di lapangan masih muncul sifat dan sikap saling mencela, dan kekerasan yang mengatasnamakan agama Islam.
Upaya Pemerintah Daerah Kabupaten Temanggung Dalam Mendorong Eksistensi dan Peningkatan Koperasi
Authors: Hidayat Farid
Published: January 2020

Perkembangan perekonomian di Indonesia tidak bisa lepas dengan adanya perkembangan koperasi. Dari tahun ke tahun perkembangan koperasi mengalami pertumbuhan atau peningkatan, baik dari jumlah koperasi maupun koperasi yang aktif, sedangkan koperasi yang tidak aktif mengalami penurunan. Berdasarkan jenis usahanya terdapat berbagai macam jenis koperasi, yaitu koperasi simpan pinjam, koperasi serba usaha, koperasi jasa dan koperasi konsumsi. Adapun tujuan dari penelitian ini adalah untuk mengetahui bagaimana upaya yang dilakukan Pemerintah Daaerah Kabupaten Temanggung dalam mendorong eksistensi dan peningkatan koperasi di Kabupaten Temanggung. Penelitian ini bersifat kualitatif , yaitu metode yang digunakan untuk menganalisis data-data yang bersifat kualitatif yang digambarkan dengan kata-kata atau kalimat dipisah-pisah menurut kategori untuk memperoleh kesimpulan. Data yang akan digunakan adalah data primer dan sekunder, data primer diperoleh dengan melakukan pengamatan langsung dan wawancara kepada Pegawai Dinas Perindustrian Perdagangan Koperasi Usaha Kecil dan Menengah (DINPERINDAGKOP UKM), kemudian data sekunder yang digunakan adalah berupa laporan data Dinas Perindustrian Perdagangan Koperasi Usaha Kecil dan Menengah (DINPERINDAGKOP UKM). Agar koperasi tetap bisa bertahan dan meningkat, maka Pemerintah Kabupaten Temanggung melakukan pembinaan, antara lain dengan mengadakan seminar dan berupaya mengajak koperasi yang tidak aktif ini agar aktif kembali, pembinaan manajemen, memberikan pelatihan keuangan, yaitu dengan mengadakan pelatihan dasar akuntansi dan perbaikan kelembagaan koperasi.
Urgensi Pembentukan Karakter Anak di Era Globalisasi Melalui Penguatan Keluarga
Authors: Budiman Arif , Suva Pinkan Regina
Published: January 2020

Di Era globalisasi, terdapat banyak kemajuan baik dibidang IPTEK maupun sosial budaya sehingga manusia mengalami perubahan baik dari segi pola pikir dan tingkah laku yang di pengaruhi lingkungan sekitar. Untuk menjaga karakter manusia yang sesuai dengan norma yang berlaku di masyarakat, perlu adanya pendidikan karakter pada anak dikarenakan pada usia anak-anak merupakan tingkat keemasan yang memiliki potensi alami yang baik untuk dikembangkan berupa pengetahuan disertai dengan kesadaran, emosi dan perasaannya. Pendidikan karakter anak dimulai dalam ranah keluarga dan diaplikasikan melalui pola asuh masing-masing orang tua kepada anaknya. Jenis pola asuh dalam ilmu psikologi ada 3 yakni otoriter, permisif dan demokratis. Pengabdian masyarakat di Dusun Ngelorejo Desa Srumbung Kecamatan Srumbung Kabupaten Magelang perlu diadakan Sosialisasi pembentukan karakter pada anak yang bertujuan untuk mengidentifikasi peranan dan jenis pendekatan keluarga dalam membentuk karakter anak agar menjadi generasi taat akan norma-norma yang berlaku. Pendekatan yang digunakan kualitatif dengan metode sosialiasi. Berdasarkan hasil observasi dan wawancara, para orang tua disana memiliki jenis pola asuh otoriter dan permisif. Pola asuh otoriter merupakan pola asuh yang keras dan menerapkan komunikasi satu arah sehingga menjadikan anak memiliki sifat tertutup, kurang percaya diri, dan kurang mampu mengekspresikan dalam melakukan kegiatan. Sementara pola asuh permisif memberikan kebebasan tanpa memberikan norma masyarakat sehingga menjadikan anak memiliki sifat egois, kurang peka terhadap lingkungan dan kurang dapat menerapkan nilai-nilai masyarakat. Hasil penelitian menunjukkan bahwa orang tua memiliki peranan penting dalam pendidikan karakter anak, memberikan pola asuh yang tepat disertai kasih sayang, kedisiplinan, nasehat, dan keteladanan.
EFFECT OF CONCRETE CREEP ON THE SHORTENING OF VERTICAL ELEMENTS IN HIGH-RISE BUILDINGS
Authors: Chaaban Sandy , Baalbaki Ousama , Temsah Yehya
Published: January 2020

Vertical structural elements are commonly subjected to the time-dependent behavior effects caused by creep which causes shortening in these elements in the direction of the load being applied. Significant amount of creep takes place instantaneously with loading and carries on for the long-term dimensions. In high-rise buildings, the axial shortening in columns is inevitable, so it cannot be ignored. The shortening is differential between vertical structural members due to the difference in axial stiffness and load distribution areas on these elements. Conventional structural analysis assumes that all structural loads are instantaneously applied to the entire completed structure. The construction sequence and loading sequence may be different depending on the construction plan. Therefore, the actual structural behavior can be significantly different from the conventional analytical behavior based on the above assumption. The objective of this study is to highlight the effect of concrete creep behavior on the shortening of vertical elements specifically in high-rise buildings. In this study, we will be considering the ACI 209R-92 model. Based on experimental data, a procedure is developed to compute the elastic shortening due to creep. A 250 meters high-rise is studied taking into consideration the stress and modulus of elasticity depending its construction time and height.
EVALUATION OF CREDIT ACHIEVEMENTS OF LEED-CERTIFIED BUILDINGS
Authors: Polat Gul , Turkoglu Harun , Gurgun Asli Pelin , Yikilmaz Naz
Published: January 2020

Nowadays, the concept of green building is no longer an alternative but a necessity. The acceptance of a building as “green” depends on having a certificate. LEED is one of the widely used green building certification systems in Turkey. The main objective of this study is to find out whether there were statistically significant differences between the credit achievements of 105 newly constructed and certified buildings in Turkey, which were certified according to four different levels, and to determine which of these credit achievements are weak. For this purpose, Kruskal-Wallis and Mann-Whitney U tests were performed and the findings were interpreted. Findings revealed that the highest level of achievement of these buildings was in sustainable sites, water efficiency, innovation in design, and regional priority credits, while the lowest level of achievement was in energy and atmosphere, materials and resources, and indoor environmental quality credits. Analyses revealed that the achievements in the energy and atmosphere, materials and resources, and indoor environmental quality credits of green buildings are relatively low when compared to the ones in other credits. There may be several reasons behind these low levels of achievement such as poor green culture, high investment cost of necessary systems, absence of reusable, recycled, and renewable materials. If these problems, most of which are peculiar to developing countries, can be overcome, higher certification levels can be achieved.
EVALUATION OF SIMULATION TECHNIQUES FOR MODELING PROGRESSION OF CONSTRUCTION CLAIMS
Authors: Barakat Mohammad , Khoury Hiam , Abdul-Malak Mohamed-Asem
Published: January 2020

The unstructured and dynamic nature of construction projects and the on-site work complexities have been inevitably leading to claims. These evolve according to a staged mechanism set forth in the adopted conditions of contracts. More specifically, claims might progress expeditiously or drag depending on the nature of the applied mechanism and the behavior and interaction among contractual parties. As such, this complex problem of claim progression, which entails a lot of parameters and variables, is addressed in detail in this paper by resorting to three simulation techniques namely: (1) Discrete-Event Simulation (DES), (2) Agent-Based Modeling (ABM), and (3) System Dynamics (SD). The purpose behind this study is two-fold: (1) capturing and visualizing, through three different simulation models, the dynamic and interaction among the different entities as claims are progressing and defining the weak links hindering the efficiency improvement of such a process, and (2) comparing DES, ABM, and SD simulation approaches, using choose-by-advantage technique, and evaluating the advantages and drawbacks of each when studying the progression of claims. Results of all approaches are presented and analyzed followed by a discussion of the effectiveness of each simulation technique and the potential applicability of a hybrid approach in modeling the progression of claims.