bluuebunny/crossref_metadata_2025 huggingface dataset:
Сase of neonatal lupus in one of two children of dichorial diamniotic pregnancy in a woman with unrecognized systemic lupus erythematosus and lupus nephritis
Authors: Kirsanova T. V. , Kravchenko N. F. , Balakireva A. I.
Published: February 2020

The ability to realize the reproductive function for both patients with systemic lupus erythematosus and patients with a different cause of chronic kidney disease is rightfully considered as one of the most important achievements of modern medicine. The work describes the pregnancy case of the patient with systemic lupus erythematosus and secondary antiphospholipid syndrome. Renal damage with the development of renal thrombotic microangiopathy came to the fore in the clinical picture, which was regarded as nephritis and complicated the diagnosis of systemic lupus erythematosus. A positive pregnancy outcome was achieved with the development of neonatal lupus erythematosus in one twin child. The options for the prevention and treatment of thrombotic complications as well as methods for minimizing gestational complications (including preeclampsia, which the patient had in history) are discussed, inter alia, with the purposed of low-molecular-weight heparins and acetylsalicylic acid preparations. Treatment options are also described to improve the outcome of such pregnancies and to decrease the symptoms of neonatal lupus erythematosus using hydroxychloroquine. The article summarizes current management approaches for these patients with special attention to the interdisciplinary approach.
Kidney health for everyone everywhere from prevention to detection and equitable access to care
Authors: Kam-Tao Li Philip , Garcia-Garcia Guillermo , Lui Siu-Fai , Andreoli Sharon , Fung Winston Wing-Shing , Hradsky Anne , Kumaraswami Latha , Liakopoulos Vassilios , Rakhimova Ziyoda , Saadi Gamal , Strani Luisa , Ulasi Ifeoma , Kalantar-Zadeh Kamyar
Published: February 2020

The global burden of chronic kidney disease (CKD) is rapidly increasing with a projection of becoming the 5th most common cause of years of life lost globally by 2040. Aggravatingly, CKD is a major cause of catastrophic health expenditure. The costs of dialysis and transplantation consume up to 3% of the annual healthcare budget in high-income countries. Crucially, however, the onset and progression of CKD is often preventable. In 2020, the World Kidney Day campaign highlights the importance of preventive interventions – be it primary, secondary or tertiary. This complementing article focuses on outlining and analyzing measures that can beimplemented in every country to promote and advance CKD prevention. Primary prevention of kidney disease should focus on the modification of risk factors and addressing structural abnormalities of the kidney and urinary tracts, as well as exposure to environmental risk factors and nephrotoxins. In persons with pre-existing kidney disease, secondary prevention, including blood pressure optimization and glycemic control, should be the main goal of education and clinical interventions. In patients with advanced CKD, management of co-morbidities such as uremia and cardiovascular disease is a highly recommended preventative intervention to avoid or delay dialysis or kidney transplantation. Political efforts are needed to proliferate the preventive approach. While national policies and strategies for non-communicable diseases might be present in a country, specific policies directed toward education and awareness about CKD screening, management and treatment are often lacking. Hence, there is an urgent need to increase the awareness of the importance of preventive measures throughout populations, professionals and policy makers.
Experience Numerous benefits of Water-based activity in The Island of God
Authors: Januar Rizky
Published: February 2020

Starting to do exercise must be challenging, especially for someone who is not used to it. Therefore, combining physical activity and vacation is a perfect option for a beginner. Water sport may be a perfect choice to spend a holiday while train body back into its perfect condition. A getaway trip to Bali Is not only about staying in luxury hotels or villas, Wine and dine on a famous beachfront restaurant, or shopping in the heart of Seminyak shopping centers. The exotic island on the equator offers a wide selection of water recreation with dozen of benefits for those health seekers. This writing is a descriptive study. The findings from previous studies which discussing vacation and water-related exercise were compiled as data. Bali was served as tourism object where this study is undertaken. Then, the compiled data were used to describe the benefit of recreation in Bali as the tourism object and its water activity for health. The Island of Bali, known for its breathtaking landscape and as the best tourist destination, offers additional choices to tourists who wished to travel while getting extra benefits for their health. Some studies revealed there are numerous advantage someone may obtain by doing physical activity in the water, such as improvement in cardio, respiratory, and muscle strength. The activity also promotes full body workout to help overcome weight problem, both under and overweight while holiday in Bali helps the traveler to take a break from the tedious yet stressful environment.
Bali Included as ‘No List 2020’, a Shocking news on the end of 2019
Authors: Setiawan Ida Bagus Putra
Published: February 2020

A US-based tourism magazine ‘Fodor’ includes Bali as ‘No List 2020’. The news infuriated Bali Governor Wayan Koster. Koster presumed the action was an example of foul play in tourism competition. Meanwhile,  Minister of Tourism and Creative Economy, Wishnutama Kusbandio claimed he did not bother with the Fodor's review. The news might be the Fodor’s strategy as a media to reach a wider audience. Fodor’s included Bali as "No List 2020" due to three major factors namely poor waste management, clean water existence, and foreign tourists’ disrespectful attitude. Findings showed what the media wrote apparently reflects the todays reality on th Island of Gods. However, the local Government has been starting to make significant improvement from waste management, and tourism standard. Tourism stakeholder in Indonesia especially Bali, might be infuriated by Fodor’s No List 2020. Rather than to negatively response to the news, it is better to consider it as positive feedback for Bali tourism. In addition, a good quality feedback from media as one of society control would be well appreciated if it is providing problem-solving solution instead of only focus on critics.
CRIMINALS AMONG THE WOMEN IN THE FERGHANA VALLEY AND ITS NEGATIVE EFFECTS
Authors: Makhsudovna Nosirova Marguba
Published: February 2020

In this article is discussed process of criminals among the women in the Ferghana valley and its negative effects by the media sources and materials of juridical documents as well.
KEY WORDS: Ferghana valley, women, nationality, upbringing, morality, ethics, Gender, result, offence.
ROLE OF PREAMBLE IN DEVELOPING ‘THE LIMITED THEORY OF AMENDMENT’ IN INDIA
Authors: Khirale Dr.N.M.
Published: February 2020

The Preamble to the constitution has a noble vision which is reflected in the body of constitution in two parts. Chapter on fundamental rights and directive principles both are constitutional goals. The foundation of welfare state and democratic setup is a basic feature which directs state machinery to respect the way, access to exercise of right to life of millions in India. The Supreme nature of the constitution, Republic and Democratic form of Government. Secular in itself and partially adoption of theory of Separation of powers with Federal character are the basic elements of the constitution which can easily be understand by anybody by simply reading the contents of the preamble.
The Constitution-makers with legitimate voice finalized the competency parliament to make amendments in rights to cater the present needs of nation and also to find remedial measures for the problems of socio-economic progress and development of the country.
KEYWORDS: Preamble, Basic structure, Amending powers, limited power theory.
Effect of Low Level Laser Therapy (LLLT) on Pain, Trismus and Quality of Life (QOL) in Post Lower Third Molar Removal Patients : A Randomized Controlled Trial
Authors: Andi Dala Intan  , Nyoman Murdana  , SA Nuhonni  , Lilies Dwi
Published: February 2020

Background: Low-Level Laser Therapy (LLLT) is a physical modality used in a rehabilitation support service. Patients with lower third molar impacted experience decline in QOL due to inflamatory response,such as bleeding, swelling, stiffness and pain. This leads to disability in daily activities, such as eating and drinking during several days post removal.Methods: It is a randomized controlled trial (RCT) and single blind study. A total of 21 subjects in LLLT and 21 subjects in control groups with the age range of 18-30 years. Subjects in the study group were given a totaldose of 54 J, energy density 18J/cm2 on day 0, 3 and 7 post lower third molar impacted surgery. Both groups were assessed for QOL values using the Short Form 36 (SF-36) before and after therapy.Result: Decrease in Pain (VAS) and Trismus on the third and seventh day post operatively were statistically significant (p <0.05) between the two groups. QOL improvement on the SF-36 domains of Role Physically(RP), Bodily Pain (BP), General Health (GH) was statistically significant (p <0.05) in both groups. Moreover, QOL improvement in Physical Components (PCS) was also significant between the two groups.Conclusion: LLLT could reduce postoperative pain of lower third molar impacted patients from day 0 to 3 and completely painless on the seventh day postoperatively. LLLT therapy eliminated Trismus on the third dayafter the surgey. Increase QOL in patients with lower third molar impacted removal after LLLT was evident in the physical component. The positive changes in pain and trismus reduction, also QOL improvement postLLLT can restore patients’ activities of daily living as usual in a short period of time.Keywords : Low Level Laser Therapy (LLLT), Pain, Trismus, Quality of Life, Rehabilitation, Lower Third Molar Removal.
Correlation of Thorax Expansion with Heart Rate and Blood Pressure in School-Aged Children
Authors: Pipit Wandini  , Ellyana Sungkar  , M. Rizki Akbar
Published: February 2020

Background: Thorax expansion used to measure respiratory function. Data of thorax expansion for healthychildren is still limited. Thorax expansion is caused by breathing. This influences cardiovascular functionbecause anatomically the heart is located within the thorax cavity. The aim of this study is to determine themeasurement of thorax expansion using the measurement tape method. Factors influencing thorax expansionare sex and age; and correlates with heart rate and blood pressure in school age children.Methods: Ninety-six children were included in this study both male and female and were aged 6 to 15years. They were in Elementary School and Junior High School in Jatinangor. The study were conductedfrom September-November 2013 by adopting a random selection cross sectional method. The examinationsperformed after written informed consent and questionnaire form from their parents.Results: The results showed that upper thorax has lower mean expansion than middle and lower thoraxexpansion respectively (2.96±0.64cm; 3.82±1.04cm; 5.01±1.15cm). There was significant difference betweengroups of age (p<0.05). This study also found that there was a correlation between the upper and middle thoraxexpansion with the heart rate (r=0.35; p=0.001, and r=0.32; p=0.002).Conclusions: The mean of thorax expansion at upper, middle and lower respectively (2.96±0.64cm;3.82±1.04cm; 5.01±1.15cm) are influenced by age and has correlation with heart rate.Keywords: blood pressure, heart rate, school-aged children, thorax expansion.
Relationship between Calcium Deposit Size with the Pain Intensity in Patients with Calcified Rotator Cuff Tendinitis
Authors: Indri Wijayanti  , I Nyoman Murdana  , Tirza Z. Tamin
Published: February 2020

Background: Calcified tendinitis is a disease characterized by calcification of multifocal cells mediated byliving tissue. Calcified tendinitis may occur due to the collection of calcium in the supraspinatus tendon pouchor may be spread between rotator cuff muscle fibers and bursa, it may not cause pain or may cause mild painor discomfort. The aim is to determine the correlation of calcium deposit size to the pain intensity in patientswith calcified tendinitis.Methods: Methods in this study was a cross-sectional study, twenty subjects, aged 50-70 years old, diagnosedwith calcified tendinitis rotator cuff through musculoskeletal ultrasonography examination.Results: No significant correlations were found between calcium deposit size and pain intensity using VAS,r=0.238, p=0.312.Conclusion : The size of the calcium deposit was not correlated with the pain intensity in rotator cuff calcifiedtendinitis patients. But further research is needed whether the location and form of calcium deposits affect thepain intensity in calcified tendinitis rotator cuff patients.Keywords: calcified tendinitis; calcium deposit size; pain intensity.
Higher Body Mass Index and Waist Cicumference Have Correlation With the degree of Curvature of Hyperlordosis in Young Adult
Authors: Fitriani Rahmawati  , Nuryani Sidarta
Published: February 2020

BACKGROUND : Health problem that caused by higher BMI have grown broadly. Musculoskeletaldisorders due to higher BMI will cause an excessive burden on the lumbosacral joints. .Moreover, excess waistcircumference can also lead to malformation of lumbal curvature.Purpose: This study aims to determine the relationship between higher Body Mass Index (BMI) and excesswaist circumference with the higher curvature in young adult.Method: This study used observational study with cross-sectional design involving 88 students whoperformed measurement of body weight, height, and waist circumfrences, also lumbar curve examination. Themeasurement of waist circumference was done by circling the flexible tape on waist. For the measurement ofthe lumbar curve,each respondent is measured by a flexible ruler.Results: chi square test obtained p = 0,000 in high BMI with the increasing of lumbar curve and p = 0,000 inexcess waist circumference with the increasing of lumbar curve. So, there is a correlation between higher BMIand excess waist circumference with the increase of lumbar curve in the young adults.Conclusions: In this study showed that higher BMI and excess waist circumference have correlation with theincrease of lumbar curve in the students.Keywords: body mass index, waist circumference, tape measure, hyperlordosis, flexible ruler.
Teenager in conflict with the Law: addiction and impulsivity
Authors: María de los A Quiroga
Published: February 2020

This is a 17-year-old boy, who started substance use from an early age. In childhood I have behavioral disorders with poor school performance and poor socio-environmental stimulation, in the context of a highly dysfunctional family with the absence of continental adult figures. His criminal record is recorded from the age of 8 years and substance use from 12 years. The difficulty arose in the Court whether or not it was attributable. Finally, he was imputed. After the studies, it turned out that the young man according to the DSM V was structuring a psychopath personality.

Keywords: Teenage; Impulsivity; Abuse toxic substance
HISTORIA BADAŃ NAD DETERMINACJĄ PŁCI
Authors: Piprek Rafał , Kubiak Jacek Z.
Published: February 2020

Jedną z podstawowych kwestii, które intrygowały i fascynowały ludzkość od zarania dziejów jest to, skąd wywodzą się różnice między płciami. W dziełach starożytnych filozofów odnajdujemy próby intuicyjnego lub wręcz poetyckiego wyjaśnienia pochodzenia cech odróżniających mężczyzn od kobiet. Wykrycie mechanizmów kierujących rozwojem płciowym zawdzięczamy zastosowaniu metod naukowych, które były rozwijane przez stulecia i osiągnęły swój szczyt dopiero w XX w. Wśród kamieni milowych w badaniach nad determinacją płci należy wymienić przede wszystkim odkrycie chromosomu X w XIX w., opisanie udziału chromosomów płciowych w determinacji płci na początku XX w., uznanie w latach 50. chromosomu Y za chromosom determinujący płeć męską u ludzi, oraz odkrycie w 1990 r. genu SRY determinującego u ssaków płeć męską.
EPIGENETYKA A ODPOWIEDŹ ROŚLIN NA STRES I ROZWIJANIE ZDOLNOŚCI ADAPTACYJNYCH
Authors: Tomczyk Przemysław
Published: February 2020

Prowadzone intensywnie na całym świecie badania dostarczają coraz więcej informacji na temat związków procesów epigenetycznych ze zmianami w środowisku. Procesy epigenetyczne pozwalają organizmom żywym zmieniać sposób odczytywania genów, bez bezpośrednich zmian w samej sekwencji genów. Procesy te są również kierunkowe, określona zmiana w środowisku wywołuje mechanizm epigenetyczny, który pomoże organizmowi poradzić sobie z tą zmianą. Niniejsza praca ma na celu zebranie i usystematyzowanie wiedzy o działaniu zjawisk epigenetycznych u roślin podczas stresu i w rozwijaniu adaptacji długoterminowych. Publikacja zawiera opis mechanizmów epigenetycznych, uwzględnia aspekt poliploidalności (bardzo częsty u roślin) oraz opisuje jak zjawiska te mogą wpływać na ewolucję tych organizmów. Przedstawiono przykłady epigenetyczych adaptacji roślin do środowiska oraz odpowiedzi na stres abiotyczny i biotyczny. Zaprezentowano również perspektywy zastosowań epigenetyki w ochronie przyrody i w rolnictwie.
ŻYCIE I ŚMIERĆ PÓŹNOJURAJSKICH SKRZYPŁOCZY (XIPHOSURA) Z OWADOWA-BRZEZINEK W ŚWIETLE INTERDYSCYPLINARNYCH BADAŃ PALEOŚRODOWISKOWYCH
Authors: Błażejowski Błażej , Gieszcz Piotr , Tyborowski Daniel , Siuda Robert , Kwiatek Jerzy
Published: February 2020

Skrzypłocze (Xiphosura) są jednymi z najdziwniejszych istot w królestwie zwierząt. Grupa ta, współcześnie obejmująca cztery reliktowe gatunki, przetrwała właściwie niezmieniona od ordowiku (480 milionów lat), i była świadkiem masowych wymierań, stąd powszechnie używana jest jako przykład „żywych skamieniałości” lub „stabilomorfów”. Niniejsza praca poświęcona jest opisowi nowych i doskonale zachowanych skamieniałości skrzypłoczy z górnej jury (tyton) kamieniołomu Owadów-Brzezinki, który jest jednym z najważniejszych stanowisk paleontologicznych opisanych w ostatnim czasie w Polsce. Kamieniołom ten znany jest z wyjątkowo dobrze zachowanych skamieniałości organizmów morskich i lądowych. Odkrycie licznych okazów młodocianych skrzypłoczy w kamieniołomie Owadów-Brzezinki stanowi istotny wkład w badania nad paleobiologią tych stawonogów oraz paleoekologią ich środowiska życia. Praca ta podsumowuje ostatnie badania nad tymi unikatowymi skamieniałościami i tym, jaki wkład badania te wnoszą w lepsze poznanie tej grupy zwierząt. Szczegółowe oględziny doskonale zachowanych egzoszkieletów tych skrzypłoczy, a także analiza osadu, w którym je znaleziono, pozwoliły na stworzenie scenariusza paleośrodowiskowego, według którego najbardziej prawdopodobną przyczyną epizodu masowej śmiertelności skrzypłoczy była infekcja glonowa.
ANTROPOCEN, WIELKIE PRZYSPIESZENIE I INSEKTAGEDON
Authors: Ptaszyńska Aneta A.
Published: February 2020

Żyjemy w epoce wielkich przemian spowodowanych przez człowieka zarówno w geologii Ziemi, jak i w ekosystemach. Zmiany te są na tyle istotne, że jesteśmy świadkami narodzin nowej epoki, antropocenu. Epoka ta napędzana jest „Wielkim Przyspieszeniem”, w którym wzrostowi ulega przede wszystkim populacja ludzka, co skutkuje w drastycznym zwiększeniu zapotrzebowania na energię, ziemię i wodę. Rozrastająca się populacja ludzka wkracza na tereny dotąd zamieszkiwane przez inne organizmy i wypiera je z ich naturalnych siedlisk. Doprowadziło to do szóstego wielkiego wymierania i insektagedonu. Tempo przemian jakim ulega obecnie biosfera jest bardzo szybkie i niewątpliwe należy podjąć odpowiednie działania zmierzające do ochrony Ziemi i organizmów żywych.
ISOLASI BAKTERI PLANT GROWTH PROMOTING RHIZOBAKTERIA (PGPR) LOKAL DARI ENDOFIT AKAR TANAMAN KELAPA SAWITDAN UJI ANTAGONIS TERHADAP PENYAKIT JAMUR AKAR PUTIH
Authors: Walida Hilwa
Published: February 2020

White root fungus disease has become the most damaging root disease in rubber trees in both Africa and Asia that supplies 98% of rubber products to the world market. Chemical control by using pesticide was a common root control of white root fungus. PGPR (Plant Growth Promoting Rhizobacteria) could be one of the solutions in biological control of environmentally to against white root fungi. The aims of yhis study were to obtain isolates of local PGPR bacteria from the root endophytes of oil palm trees, to know the morphological characteristics of local PGPR isolates from root endophytes of oil palm plants, and to know the potential of biological control agents againts white root fungus disease. This research was conducted by using descriptive analysis method. The results showed that there were 9 bacterial isolates from the root endophytes of oil palm plants with different macroscopic morphological characteristic and there were 9 isolatesable to inhibite the growth of white root fungus with the biggest potential was A5 isolate. Keywords : PGPR, Root Endophytes of Palm Oil Plant, Rigidoporus microporus
KUALITAS PELAYANAN LABORATORIUM MIKROBIOLOGI FAKULTAS KEDOKTERAN UNIVERSITAS GADJAH MADA YOGYAKARTA
Authors: Yauharoh Siti , Utami Sri
Published: February 2020

Penelitian ini bertujuan untuk mengetahui kualitas layanan Laboratorium Mikrobiologi Fakultas Kedokteran, Universitas Gadjah Mada (UGM), dan untuk mengetahui faktor-faktor yang mempengaruhi kualitas layanan. Penelitian ini dengan pendekatan deskriptif kualitatif menggunakan metode observasi, wawancara, dokumentasi dan studi literatur. Berdasarkan hasil data penelitian disimpulkan bahwa kualitas layanan di Laboratorium Mikrobiologi Fakultas Kedokteran UGM cukup baik, ini terlihat dari indikator kualitas layanan: Reabilitas cukup baik; Responsif cukup baik; kepercayaan diri itu baik; empati itu baik, dilihat dari ketegasan dalam menolak dan menerima sampel; berwujud tidak baik. Faktor penghambat kualitas layanan di Laboratorium Mikrobiologi Fakultas Kedokteran, UGM meliputi: Sumber daya manusia yang bertugas menerima sampel yang kurang terampil, SOP belum tersedia untuk penerimaan sampel, sebagian besar alat yang digunakan di laboratorium masih manual, Sistem Informasi Laboratorium belum tersedia. fasilitas di ruang tunggu belum tersedia, ruang penerimaan sampel tidak memenuhi kriteria keselamatan staf, lokasi penerimaan sampel jauh, tempat untuk mengirim sampel tidak jelas, tidak ada pesanan sesuai dengan jenis/tipe pemeriksaan.
KEGAGALAN POLITIK UMNO DALAM PEMILIHAN RAYA UMUM KE - 14
Authors: Nizar Moh
Published: February 2020

Selama lebih dari enam dasawarsa, UMNO (United Malays National Organization) dan koalisinya (Barisan Nasional) menguasai panggung ekonomi politik Malaysia. Kekuasaan ini dibangun atas ideologi sektarian keistimewaan suku Melayu dengan komposisi lebih dari 50% daripada ras, bangsa dan suku lainnya. Namun, pengukuhan kekuasaan ini berlangsung dengan penuh ketegangan politik, di antaranya yang terpenting adalah kerusuhan rasial pada tanggal 1 Mei 1969. Akumulasi pertentangan internal dan masalah ekonomi politik nasional telah menggerogoti partai berkuasa Malaysia terlama di dunia ini sejak Pilihan Raya ke-13. Mahathir Mohammad, sebagai seorang pembangun UMNO terpenting, memasuki kembali politik Malaysia setelah dua periode Perdana Menteri Malaysia dengan membentuk partai dan koalisi baru. PRU-14 (2018) membuktikan kekalahan UMNO dan kemenangan Mahathir dengan koalisinya. Sarana baru dalam perkembangan teknologi informasi digunakan oleh Mahathir untuk menarik dukungan rakyat Malaysia yang sudah sangat kecewa dan bosan terhadap korupsi kekuasaan UMNO.
INOVASI PRODUK PEMANFAATAN LIMBAH KULIT PISANG UNTUK MENINGKATKAN PENDAPATAN
Authors: Mauludin Hanif , Puspita Dyah Aruning
Published: February 2020

Abstrak

Daya saing masih menjadi isu utama dalam usaha kecil menengah. Salah satu modal daya saing adalah inovasi. Program Pengabdian masyarakat dalam paper ini adalah mengusung tema inovasi produk melalui pemanfaatan limbah kulit pisang menjadi krupuk pisang. Kegiatan pengabdian ini dilakukan di Desa Kedungsalam Kecamatan Donomulyo Kabupaten Malang. Kegiatan ini melibatkan mitra yaitu usaha kecil menengah yang memproduksi aneka makanan berbahan dasar pisang. Kegiatan yang disponsori oleh departemen riset Pemerintah Indonesia memberikan bantuan teknis dengan tujuan meningkatkan capacity building.  Inovasi produk berupa krupuk kulit pisang mampu meningkatkan produktivitas usaha.. Daya saing usaha juga meningkat selaras dengan bertambahnya variasi produk. Potensi pasar juga semakin luas bahkan berpotensi untuk ekspor.

 

.Keywords: limbah industri, Inovasi produk, produktivitas usaha kecil menengah
WORKSHOP MEDIA PEMBELAJARAN MATEMATIKA BERBASIS ICT MGMP MATEMATIKA SMA KABUPATEN TRENGGALEK
Authors: Nasution Syaiful Hamzah , Andaini Susy Kuspambudi , Nurhakiki Rini , Permadi Hendro , Slamet Slamet
Published: February 2020

Saat ini ICT banyak digunakan dalam pembelajaran. Beragam software matematika seringkali digunakan sebagai media pembelajaran untuk membantu siswa dalam memahami konsep matematika. Salah satu software yang banyak digunakan dalam pembelajaran adalah GeoGebra. Berdasarkan hasil wawancara dengan ketua MGMP Matematika SMA Kabupaten Trenggalek diperoleh informasi bahwa sebagian besar guru matematika SMA di Kabupaten Trenggalek belum banyak memanfaatkan GeoGebra dalam pembelajaran. Hal tersebut menjadikan alasan dilaksanakannya pengabdian kepada masyarakat (PkM) ini. Kegiatan PkM ini bertujuan untuk memberikan dasar pembuatan media pembelajaran matematika menggunakan software GeoGebra. Kegiatan ini dilakukan dalam tiga tahap: (1) analisis kebutuhan, (2) pelaksanaan workshop secara tatap muka, dan (3) pendampingan pembuatan media pembelajaran matematika menggunakan GeoGebra secara online. Materi workshop yang disampaikan meliputi: (1) instalasi software GeoGebra, (2) mengenal area kerja GeoGebra, (3) tools pada GeoGebra, (4) membuat objek menggunakan GeoGebra, (5) pengenalan slider, dan (6) dasar animasi pada GeoGebra. Hasil dari pelaksanaan PkM ini adalah: (1) guru matematika SMA Kabupaten Trenggalek mengenal software GeoGebra dan dapat melakukan instalasi GeoGebra, (2) guru matematika SMA Kabupaten Trenggalek dapat menggunakan GeoGebra, dan (3) guru matematika SMA Kabupaten Trenggalek dapat membuat media pembelajaran matematika menggunakan GeoGebra.
EFEKTIVITAS PEMBERIAN EKSPRESIF WRITING THERAPY TERHADAP KECENDERUNGAN SELF INJURY DITINJAU DARI TIPE KEPRIBADIAN INTROVERT
Authors: Faried Laila , Noviekayati IGAA , Saragih Sahat
Published: February 2020

Self injury merupakan bentuk perilaku yang disengaja untuk melukai atau menyakiti diri sendiri, yang bertujuan untuk mengurangi penderitaan secara psikologis. Self injury juga dipengaruhi oleh tipe kepribadian. Tujuan dari penelitian ini adalah untuk mengetahui efektifitas pemberian ekspresif writing therapy terhadap kecenderungan self injury dan hubungan antara kepribadian introvert dengan kecenderungan self injury. Metode penlitian ini jenis Quasi Eksperimen dengan one group pretest postest design. Subjek dalam penelitian ini ada 10 remaja perempuan. Manfaat penelitian sebagai sarana untuk merefleksikan pikiran dan perasaan terdalam terhadap peristiwa yang tidak menyenangkan pada subjek. Teknik pengumpulan data menggunakan angket yang disusun oleh peneliti. Hasil uji Wilcoxon Signed Ranks Test diketahui nilai z =2,670, dengan Signifikansi sebesar 0.008 , yang artinya < 0.05 maka disimpulkan bahwa ada perbedaan yang sangat signifikan kecenderungan sebelum dan sesudah pemberian Terapi Ekspresif Writing pada kecenderungan self Injury. Hasil uji spearman ditemukan koefisien korelasi sebesar 0,497 dengan signifikansi sebesar 0,072 sehingga dapat disimpulkan bahwa tidak ada hubungan antara kepribadian introvert dengan kecenderungan self injury. Kata kunci : Self injury, Ekspresif Writing Therapy, Introvert, remaja
PENGARUH DUKUNGAN SOSIAL TERHADAP TINGKAT KECEMASAN IBU HAMIL DI RUMAH SAKIT BERSALIN PEMERINTAH KOTA MALANG
Authors: Utomo Yohanes Didhi Christianto , Sudjiwanati Sudjiwanati
Published: February 2020

Kehamilan merupakan saat-saat yang dinantikan oleh seorang wanita yang telah menikah dan bagi seorang wanita kehamilan merupakan suatu bentuk perwujudan kesempurnaan  karena akan mendapatkan keturunan. Dalam proses kehamilan terjadi perubahan secara biologi, fisiologi dan psikologi. Secara psikologi, wanita hamil dapat mengalami stres dan kecemasan yang diakibatkan oleh proses adaptasi wanita terhadap kehamilannya. Kecemasan yang dialami oleh wanita hamil dapat mempengaruhi perkembangan janin, tekanan darah tinggi dan sesak nafas dan bila tidak segera ditangani dapat membahayakan ibu dan janinnya. Dukungan sosial merupakan suatu bentuk bantuan yang diberikan kepada individu untuk melindunginya dari konsekuensi stres. Bentuk dukungan sosial dapat berupa dukungan emosional, dukungan penghargaan, dukungan instrumental dan dukungan informasi. Dukungan sosial diharapkan dapat membantu wanita hamil menghadapi kecemasan selama proses kehamilan.Penelitian dilakukan dengan mengambil sampel sebanyak 45 wanita hamil yang memeriksakan diri di Rumah Sakit Bersalin Pemerintah Kota Malang. Metode penelitian menggunakan Skala Linkert, dan hasilnya di analisa dengan menggunakan program IBM SPSS versi 20. Hasil analisa regresi linier menunjukkan bahwa F hitung sebesar 7,360 > F tabel sebesar 7,26 yang berarti bahwa ada pengaruh dukungan sosial terhadap tingkat kecemasan ibu hamil dengan nilai signifikansi 0,01 (p=0,01). Hasil uji korelasi menunjukkan adanya korelasi negatif (r=-0,311) yang berarti dukungan sosial yang diberikan kepada ibu hamil membuat tingkat kecemasan yang dialami ibu hamil rendah.  Kata Kunci: Kecemasan, dukungan sosial, kehamilan
In-vitro Antibacterial Activity of Novel Nanostructured Composites Based on Forsterite and Silver Nanoparticles
Authors: Avram Alexandra , Gorea Maria , Rapuntean Sorin , Mocanu Aurora , Paltinean Gertrud Alexandra , Varhelyi Jr. Csaba , Petean Ioan , Horovitz Ossi , Tomoaia-Cotisel Maria
Published: February 2020

There is a continuous need for discovering new nanomaterials with antibacterial activity against various pathogens, like Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli). This study was performed to assess the antimicrobial activity of two novel nanostructured forsterites, both in the absence and the presence of silver nanoparticles (AgNPs). The two nano forsterites (FS) were prepared by advanced sol-gel (FSsg) and precipitation (FSpp) methods. Preparation of colloidal AgNPs systems was realized by using the precursor, AgNO3, and the trisodium citrate and tanic acid assuring the formation and stabilization of AgNPs. The characterization of nano forsterite powders was carried out using complementary physical methods: XRD, SEM, and AFM. The AgNPs were characterized by UV-Vis spectra, STEM and AFM imaging. The antimicrobial activity was studied by the agar well diffusion method both in the FS native state, as FSsg and FSpp, and in their mixture with silver nanoparticles (AgNPs). The inhibitory effect of synthesized forsterites, FSsg and FSpp, particularly variants with AgNPs was found only on the S. aureus strain, the zones of inhibition being between 8 and 10 mm, and more intensely expressed in the FSpp-AgNPs dispersions. These findings open new orthopedic applications of these systems, particularly for antimicrobial coated metallic implants.
Contributions on Spruce Bark Polyphenols Identification Using Instrumental (UV-VIS Spectrometry), Qualitative (Thin Layer Chromatography) and Quantitative (HPTLC Densitometry) Methods
Authors: Patrautanu Oana Alexandra , Ciuperca Oana Teodora , Popa Valentin I. , Volf Irina
Published: February 2020

This work assessed the qualitative and quantitative polyphenols profile in a crude ethanol extract separated from spruce bark (two fractions with [0.25 and 1 mm diameter) using ultrasound assisted extraction (UAE) as a green extraction method. The evaluation of phenolic acids and condensed tannins profile was performed using instrumental (UV-VIS spectrometry), qualitative (Thin Layer Chromatography, TLC) and quantitative (HPTLC densitometry) methods. Using ultrasound assisted extraction (UAE) technique under specific parameters, the higher total phenolic content (TPC) was 29.785 mg GAE/g-1 for spruce bark fraction with particle size [0.25 mm and 14.448 mg GAE/g-1 for fraction with 1 mm diameters. The TLC assay of the crude ethanol extract was performed considering the standards: gallic, sinapic, p-coumaric and vanillic acids, catechin, epicatechin and tannic acid. Smaller material particle sizes lead to higher yield of polyphenols in ethanol extract. The quantitative evaluation by HPTLC densitometry revealed following amounts: sinapic acid 0.84 mg/g, p-coumaric acid 0.61 mg/g, catechin 1.03 mg/g, tannic acid 2.81 mg/g. Considering the chemical composition, the spread and availability, spruce bark could be considered as a resource with environmental and economic benefits.
Perspectives of Silicone Elastomere Implants Use in Preventing Postoperative Complications in Pelvic Exenteration for Advanced Cancers
Authors: Jinescu George , Bacalbasa Nicolae , Evtodiev Andra , Marin Iulia-Adelina , Chiulan Ioana , Radu Elena-Ruxandra , Frone Adriana Nicoleta , Costea Ruxandra , Raita Stefania
Published: February 2020

In this work, silicone elastomer films with potential to be used as implantable pelvic prosthesis were prepared and their bioactivity was studied both in vitro and in vivo environment. Tensile tests, hardness measurement and compression analysis revealed no significant decrease of the mechanical performance after in vitro hydrolytic degradation in simulated body fluids. The in vivo biocompatibility of films was assessed by implanting them subcutaneously in swine model, for 30 days. Their mechanical characteristics were similar to those of samples immersed in simulated body fluids, for the same time interval. No sign of fibrosis or necrosis were detected from the histological analysis performed on the tissue surrounding the films. In combination, these results indicate that this material has a very good resistance to mechanical and chemical fatigue, do not release any toxic degradation products and, therefore, has great potential as to be used further for preparation of pelvic prosthesis.
Efficiency of Biocides on the Aquatic Systems Through Bacterial Model
Authors: Banciu Alina Roxana , Ionescu Lucian , Ionica Daniela Liliana , Mitru Daniel , Nita-Lazar Mihai
Published: February 2020

Various biocide technologies have been used successfully in water treatment applications for many years, but their constantly increased production and excessive usage has considerable environmental and economic impacts. In addition, the aggressive use of biocides in more and more fields such as agriculture, livestock growth, and fish farming increased the risk to public health. This measures can lead to the selection of pathogens insusceptible to the main available antimicrobials. Antimicrobials resistance is even more significant when cells are embedded in a biofilm especially in water systems. A variety of microorganisms can be found in swimming pool waters which may be introduced in a number of ways. The disinfection of bathing water is generally achieved by chlorine of chlorine-based products, but alternative more eco-friendly methods such as active oxygen are used more frequently. In this paper, compared the biocides efficiency of two compounds based on chlorine or active oxygen. Although it was assumed that the two biocides have the same mechanism of action and efficiency, we showed in this study that biocides efficiency depends on the bacterial membrane structure and the active oxygen had an increased efficacy against microorganisms compared to chlorine.
Liquid Chromatography Tandem Mass Spectrometry Method for Ultra-Trace Analysis of Organic UV Filters in Environmental Water Samples
Authors: Chiriac Florentina Laura , Paun Iuliana , Pirvu Florinela , Pascu Luoana Florentina , Niculescu Marcela , Galaon Toma
Published: February 2020

A liquid chromatography-tandem mass spectrometry (SPE-LC-MS/MS) method was developed and validated for the simultaneous determination of six organic compounds (2-hydroxy benzophenone, 4-hydroxy benzophenone, 2,2�,4,4�-tetrahydroxy benzophenone, 2,4-dyhydroxy benzophenone, 4,4�-dyhydroxy benzophenone, 2,2�-dyhydroxy-4-methoxy-benzophenone) used as UV filters in personal care products used to protect against UV radiation. The major concern about this type of pollutants is due to their persistence and bioaccumulation potential in the environment and aquatic organisms and for their endocrine disruptor properties. Solid phase extraction was used for sample preparation, followed by liquid chromatography tandem mass spectrometry analysis. Benzophenone derivatives were analyzed on a Phenomenex Luna C18 column (150 x 2.0 mm, 3.0 �m) with the mobile phase run in gradient mode with a mixture of aqueous 0.1% formic acid and acetonitrile as the mobile phase components (at a flow rate of 0.2 mL/min). MS detector response was linear, on the tested concentration domain from 1 to 100 μg/L with correlation coefficient R2 ] 0.998. The recoveries of benzophenone derivatives after solid phase extraction procedure from surface water was found to be ]81% for surface water and higher than 79% for wastewater matrix. The standard deviation values for intra-day precision were situated between 7.67% and 9.88% for lower concentration and 7.27% and 8.86% for higher concentration respectively. The limits of quantitation were calculated for both environmental water matrices (1.6-4.1 ng/L for surface water and 3.3-8.2 ng/L for wastewater). This method can be applied for benzophenone derivatives detection in real environmental samples.
Recovery of Silver and Gold From Electronic Waste by Electrodeposition in Ethaline Ionic Liquid
Authors: Popescu Ana Maria , Soare Vasile , Demidenko Olga , Calderon Moreno Jose M. , Neacsu Elena Ionela , Donath Cristina , Burada Marian , Constantin Ionut , Constantin virgil
Published: February 2020

The recycling of metals from electronic equipment waste (e-waste) is of great concern today. The work described in the article focuses on the application of ionic liquids (ILs) to selectively recover of precious metals (Ag and Au) from the anodic slime obtained at the anodic dissolution of cast e-waste. The ingots obtained from molten and cast anodic slime were selectively dissolved in ILs. Silver and gold compositions of the ingots: 39.7 wt.% and respectively 18.9 wt.%. The IL used was an eutectic mixture of choline chloride with ethylene glycol in a 1:2 molar ratio. As catalytic/oxidizing agent, there was used pure iodine in a concentration of 0.1-0.2 moldm-3 at 298-303 K. Cyclic voltammetry was employed for the determination of the electrochemical windows of ILs as well as of the dissolution and electrodeposition potentials of principal metals present in the ingot (anode). For Ag and Au, the deposition potentials determined were 0.074 V and respectively 0.696 V. The XRD and SEM-EDX analyses revealed that the content of precious metals in the cathodic deposits was 99 wt.% for Ag and respectively ]70 wt.% for Au. We demonstrated that ILs electrolytes could be a solution to selective recovery of precious metals from e-waste.
Toxicological Profile for Metals in Alzheimer Disease
Authors: Duda-Seiman Daniel , Manolache Maria-Alexandra , Duda-Seiman Corina
Published: February 2020

In this paper is presented the influence of contaminated-metals food on the Alzheimer disease. Alzheimer is a neurological disease which affects millions of people around the world. Over the time, the studies did not succeed to establish the cause that triggers the disease, but there are several factors that sustained its occurrence. One of this risk factors are the toxic metals found in the human body. The intoxication might be caused by dietary. Metals like Cd(II), Pb(II), Hg(II), Zn(II) don�t have a known biological role and the exposure to these metals is associated with neurodegenerative disorders.
Liquid-liquid Equilibrium Determination and Data Correlation for 2,2,4-trimethyl Pentane - tripropylene Glycol Binary System
Authors: Nicolae Marilena , Doicin Bogdan , Patrascioiu Cristian , Pricop Emil
Published: February 2020

Liquid-liquid equilibrium at temperatures between 293.16K and 353.1K for the mixture of 2,2,4-trimethylpentane + 2- [2- (2-Hydroxypropoxy) propoxy] -1-propanol was determined using the cloud point method. The measured data was used to estimate the binary interaction parameters of NRTL thermodynamic model, through non-linear regression using MATLAB� software. The binary interaction parameters resulting from regression were used further in a chemical simulation software (PRO/II 9.3) to determine the LLE for the studied mixture. The LLE calculation results obtained with the NRTL model were compared with the results of LLE calculations using the predictive thermodynamic model-UNIFAC. It was determined that the results of the calculation of the LLE using binary interaction parameters obtained through regression have a smaller deviation from the experimental data than the results of the calculation performed using the UNIFAC model. Moreover, the binary interaction parameters obtained from regression were utilized for the estimation of the solvency properties of tripropylene glycol considering the extraction of C8 aromatics from a mixture containing 2,2,4-trimethyl pentane, ethylbenzene and xylenes.
Facile Removal of Pesticides from Aqueous Solutions Using Magnetic Nanocomposites. II. Adsorption experiments and kinetic study
Authors: Fierascu Irina , Dima Stefan Ovidiu , Avramescu Sorin Marius , Caloian Florentin , Fierascu Radu Claudiu
Published: February 2020

Using previously presented magnetic inorganic/organic magnetic nanocomposites, the adsorption of two known commercial-available pesticides (active ingredients deltamethrin and thiamethoxam, respectively) was achieved. The differences in adsorption observed can be explained by the reduced affinity of the nitro group in the ionized form from thiamethoxam towards the carboxyl groups from chitosan. From the kinetics studies it was determined that in case of thiamethoxam adsorption process is exothermic in nature, while in the case of deltamethrin the process is endothermic. The Sips isotherm was more suitable to describe the adsorption of pesticides on prepared adsorbents. The maximum adsorption capacity determined for the developed material was 247.12 mg/g (for deltamethrin) and 53.29 mg/g (for thiamethoxam).
Small Scale Determinations for Biogas Production Using Anaerobic Fermentation - 2L Batch Scenarios
Authors: Dungan Luisa Izabel , Cioabla Adrian Eugen , Pode Vasile
Published: February 2020

Nowadays demand for clean energy and new solutions for renewable energy carriers makes it a challenge to find new substrates that can be used for production of biofuels. In this context the present paper aims to present possible solutions of substrate mixtures using materials that exist in abundance at least in the western part of Romania. Conclusions will be traced relative to material potential at small scale in terms of producing biogas.
The Influence of the Structure of Several New ortho-Hydroxy-Ketone Derived bis-Schiff Bases on Their Antibacterial and Anti-Inflammatory Activity
Authors: Tantaru Gladiola , Apostu Mihai , Ghiciuc Cristina Mihaela , Poiata Antonia , Stefanache Alina , Vieriu Madalina
Published: February 2020

The article presents some bis-Schiff bases - halogenated derivatives of ortho-hydroxy-ketones - with great potential for antimicrobial and antiinflammatory activity. The antimicrobial activities of the Schiff bases were tested in comparison with Chloramphenicol, Nystatin, and Ampicillin upon the following strains: Staphylococcus aureus (ATCC 25923), Sarcina lutea (ATCC 9341), Escherichia coli (ATCC 25922), Pseudomonas aeruginosa (ATCC 27853), Candida albicans (ATCC 1023), Candida glabrata, two Staphylococcus aureus strains, and several clinical isolates (Proteus mirabilis, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae). Those compounds were found to be active against Gram-positive or Gram-negative bacteria, and had an anti-inflammatory effect comparable to that of Indomethacin.
The Role of Non-Pharmacological Treatment for Osteoporosis at Patients with High Plasmatic Concentration of ACTH
Authors: Kese Anamaria , Barbu Mihai Constantin Razvan , Bieru Denisa Enescu , Barbu Dumitru , Berbece Sorin , Stoica Doru
Published: February 2020

Cushing disease is characterized by the hypersecretion of adrenocorticotropic hormone (ACTH) due to a pituitary adenoma that causes endogenous hypercortisolism by stimulating adrenal glands. Objective of the study was to analyse the benefits of the physical therapy for patients with ACTH-secreting adenomas osteoporosis.This retrospective study was performed at Craiova, Bunavestire Hospital, the patients were monitorized during 6 months and included 17 patients with ACTH-secretingadenomas. Participants in this study group exercised 3 days a week for 6 consecutive months. Each session is intended to take approximately 60 minutes to complete and will comprise of a warm-up, progressive resistance training using medium weights, moderate impact weight-bearing exercises, flexibility and also stretching exercises. Physical therapy for osteoporosis treatment in patients with ACTH-secreting adenomas improved joint mobility and reduced pain, significantly increasing BMD performed by DEXA in group I patients compared to patients included in group II. Pain relief is evident following evaluation using the VAS rating scale. The increase in joint mobility is observed following the goniometric measurement from day 1 to the end of treatment. Applying the physical therapy program the bone pain and joint mobility was improved, physical therapy can modify bone turnover in the sense of increasing the body mass.
Binding Affinities Studies of Nitrated Model Peptides to Monoclonal Anti-3-nitrotyrosine Antibody
Authors: Ion Laura , Lupaescu Ancuta-Veronica , Neamtu Andrei , Drochioiu Gabi , Petre Brindusa-Alina
Published: February 2020

Tyrosine nitration has been shown to be an important oxidative protein modification and play a crucial role in pathophysiological conditions, associated with oxidative stress, such as atherosclerosis and neurodegenerative disease. For a better understanding of nitration mechanism, the identification and the quantification of nitration sites represents an important research goal. Due to (i) the low levels of nitration in native proteins, (ii) structural changes induced by nitration and (iii) the specificity of anti � 3 nitro tyrosine antibodies the method which may provide the identification of nitration sites in proteins represent a challenging experimental task. In this work we have used synthetic nitrated tyrosine containing peptides to determine antibody-binding affinities and specificity of different tyrosine residue (Tyr33, Tyr98, Tyr107and Tyr122) in Eosinophil cationic proteins (ECP). The highest affinity of nitrated ECP peptides to the monoclonal antibody (anti-3NT) was obtained for the only in vivo nitrated identified residue Tyr33(0.082 �M); in contrast, all other three nitrated residues at Tyr98, Tyr107 and Tyr122) showed significant lower affinity being imbedded in the ECP protein structure as similar resulted by molecular computational modeling.
The Role of the Oxidative Stress Markers in Endotelial Dysfunction at Cardiovascular Disease Patients
Authors: Savoiu-Balint Germaine , Borza Claudia , Toth Emeric , Andoni Mihaiela , Demeter Ioan , Dejica Simina-Amelia , Neamtu Andrei , Matus Petru , Ciobanu Virgil
Published: February 2020

Although oxidative stress itself is directly associated with the occurrence of atherosclerosis, and together with endothelial dysfunction is a marker of atherosclerotic risk, none of these two markers were directly correlated with the presence of atherosclerosis. This study investigated the correlation between oxidative stress and endothelial dysfunction in people with cardiovascular disease. Furthermore, another objective of this paper is the direct study of the effect of a compound with antioxidant properties, selenium, on a model of endothelial dysfunction induced on human vascular fragments.