bluuebunny/crossref_metadata_2025 huggingface dataset:
Analisis manajemen logistik farmasi di Rumah Sakit Jiwa Grhasia Yogyakarta
Authors: Listiana Wahyu , Ruliyandari Rochana
Published: August 2024

Hospital Pharmacy Installation (IFRS) is a hospital unit as a place to carry out drug management activies. Pharmaceutical logistics management is the process of managing hospital pharmaceutical preparations ranging from planning, budgeting, procurement, storage, distribution, recording and reporting well as drug destruction in accordance with standard operating procedures. In the pharmacy installation of Yogyakarta Grhasia Mental Hospital have experienced drug vacancies in pharmaceutical logistics warehouses caused by empty stock of medicines from factories and the e- catalog process which is hampered in the procurement function the delivery or invoice inadequacy. This study aims to determine the management of pharmaceutical logistics in the Grhasia Yogyakarta Mental Hospital pharmaceutical installation. This type of research is descriptive qualitative, with a phenomenological approach. The sampling technique used is Purposive Sampling. The number of informants in this study were 5 informants consisting of the Head of the Pharmacy Installation Section, the Head of the Medical Support Services Division, the Logistics Warehouse Coordinator, and the Pharmacist as the Coordinator of drug abolition. This study uses interview guidelines and observation checklist instruments. Pharmaceutical logistics management in Yogyakarta Grhasia Mental Hospital in the implementation of the management functions of procurement, storage, distribution, recording and reporting have not run optimally in accordance with standard operating procedures. Lack of human resources and inadequate facilities become obstacles in the implementation of pharmaceutical logistics management. Pharmaceutical logistics management in pharmaceutical installation of Yogyakarta Mental Hospital Grhasia has not run optimally in accordance with standard operating procedures. The need for evaluation related to human resources and the availability of existing facilities in hospital pharmaceutical installations.
Hubungan Motivasi, Kepemimpinan, dan Budaya Organisasi Dengan Organization Citizenship Behavior (OCB) Pada Perawat Rumah Sakit Jiwa Grhasia
Authors: Candrasari Devita , Ahid Mudayana Ahmad
Published: August 2024

Background : Human resources are hospital assets that play a role in hospital services. One of the human resources in the hospital is a nurse. Nurses are front-line employees of the hospital who often interact with patients and play an important role in creating a good image of hospitals that often interact with patients by providing the best service. To achieve the highest quality of service, nurses must have a strong motivation, leaders who inspire subordinates, a culture of help to provide the best service. Nurses' attitudes and behavior in providing the best service aims to improve the effectiveness of hospital performance without ignoring individual productivity goals known as the Organization Citizenship Behavior (OCB). This study aims to determine the relationship of motivation, leadership, and organizational culture with Organization Citizenship Behavior toward nurses in Grhasia Psychiatric Hospital.
Methods : This study was a quantitative analytic research with a cross sectional design. The research subjects were nurses of Grhasia Psychiatric Hospital involved to 66 nurses. The research instrument is a questionnaire. Data analysis with unvariate and biavariate analysis.
Result: The bivariate analysis showed that there was a relationship between motivation and OCB toward nurses in Grhasia Psychiatric Hospital p-value = 0.010. There is a relationship between leadership and OCB toward nurses in Grhasia Psychiatric Hospital p-value = 0,001. There is a relationship between organizational culture and OCB toward nurses in Grhasia Psychiatric Hospital p-value = 0.031.
Conclusion: There was a relatioship of motivation, leadership, and organization culture with Organization Citizenship Behavior (OCB) toward nurses in Grhasia Psychiatric Hospital.
Analisis Waste (Pemborosan) pada Instalasi Farmasi Rawat Jalan Menggunakan Pendekatan Lean Management di RS PKU Muhammadiyah Bantul
Authors: Triyani Triyani , Syarifuddin Firman
Published: August 2024

Background: Pharmacy installation is the last unit that determines patient satisfaction in hospital services, so that the good or bad service provided will affect the related service units. Problems that often occur include slow pharmacy services, complicated procedures and difficulties for patients. Lean is an effort to eliminate waste and increase the value added of products both goods and services that take place continuously with the aim of providing value to customers. Outpatient Pharmacy Services at PKU Muhammadiyah Hospital in Bantul have not applied Lean. The purpose of this study is to find out the existence of waste in Outpatient Pharmacy Installation of PKU Muhammadiyah Hospital in Bantul
Method: This type of research is a case study with a qualitative approach. Location of research in PKU Muhammadiyah Hospital, Bantul. The subject of this study was the pharmacy manager and head of the outpatient pharmaceutical unit. The instruments in this study used observation and interview guides. Data analysis uses triangulation methods and sources.
Results: Based on Value Stream Mapping (VSM) mapping, non-racic Non Value Added (NVA) values were obtained 68.21% and 57.59%, which meant that the hospital had not been said to be lean. The critical waste that occurs is waste waiting and overprocessing. The cause of waste waitting is that the SIM sometimes has errors, many officers have double jobs, while overprocessing is caused by many repeated activities, such as repeated prescription studies and etiquette writing twice.
Conclusion: This NVA value is more than 30% indicating that the service has not been effective and efficient and there is waste. Waste that often occurs in outpatient pharmaceutical installations in PKU Muhammadiyah Bantul Hospital, namely waiting, is good for non-racial and cosmetic prescription services while over-processing occurs in non-racial prescription services.
Hubungan Faktor End User Computing Satisfaction Terhadap Kepuasan Pengguna Sistem Informasi Di Rumah Sakit PKU Muhammadiyah Kota Yogyakarta
Authors: Sinta Nur , Syam Nur Syarianingsih
Published: August 2024

Background: According to the 2011 Minister of Health, everyhospitalisrequired to implement SIRS, so that a process of collecting, processing, and presenting hospital data can be integrated. In its implementation, SIMRS is required to improve the effectiveness and efficiency of a service system. One indicator of the success of the development of information systems is user satisfaction. A number of methods to measure user satisfaction, one of which is EUCS. The general purpose of the study is to analyze the EUCS factor on system user satisfaction, while the specific purpose of this study is to see if there is a relationship between the EUCS variable factors, namely content, format, accuracy, timeliness, and ease of use with satisfaction of hospital management system users at PKU Muhammadiyah Yogyakarta in 2021.
Methods: The type of research used is quantitative research with a crosssectional design. Sampling using the lemeshow formula with the results of 245respondents. The selection of respondents used an accidental sampling technique with the research instrument using a questionnaire adopted from previous studies. Data analysis used univariate and bivariate analysis while the statistical test used was the chi square test with data categories normally distributed basedonthemedian value.
Results: From the research conducted, it is found that there is a significant relationship between 5 EUCS variables, namely content, format, accuracy, timeliness and ease of use with SIMRS user satisfaction. The results of data processing usingthechisquaretestwereobtainedabout212(86.5%)respondents who stated they were satisfied and there were about 33 (13.5%) who said they were not satisfied with the SIMRS application.
Conclusion: Overall, the five EUCS variables have a relationship and the use of the system states that they are satisfied with the My Hospital application.
Data Infrastructure for Improvement in Perioperative Medicine: Experience at a London Tertiary Hospital
Authors: Bendel Daniel , Wong Teresa , Bedford James , Odor Peter M
Published: August 2024

Adoption of electronic health record systems offers an opportunity to collate massive volumes of complex information about patient care. Healthcare data can inform performance management, enable predictive analytics and enhance strategic decision making. A data-driven approach to improving patient care is vital to address the growing burden of morbidity and mortality associated with major surgery. We describe our methodology for transforming and utilising process of care data in an electronic health record system to develop a registry for quality improvement purposes in patients undergoing major surgery at a single UK hospital. We highlight development of our data-driven vision, technical aspects of processing raw data into metrics relevant to clinical decision making, alongside challenges encountered. Finally, we outline how our data infrastructure supports clinical governance, quality improvement and research. In sharing our experiences, we hope to enable others to embed and access the transformative clinical insights that healthcare data can yield.
Research Progress on Patients of Esophageal Cancer Complicated with Sarcopenia
Authors: Fu PingPing , Xiao XiaoFang
Published: August 2024

Aims/Background The application of immunochemotherapy has significantly enhanced the quality of life and overall survival of patients with esophageal cancer. Sarcopenia, which is increasingly prevalent in these patients, markedly affects prognosis, but can be reversed by appropriate and effective treatment.

Methods The narrative review was conducted on PubMed using the keywords (“esophageal” or “esophagus” and “sarcopenia”).

Results This article reviews the measurement, timing, and intervention strategies for sarcopenia in patients with esophageal cancer. It summarizes the evaluation indicators of skeletal muscle loss in these patients, analyzes the barriers to intervention for frailty among esophageal cancer patients, and proposes corresponding countermeasures.

Conclusion Patients with esophageal cancer often suffer from severe sarcopenia. Clinical intervention is crucial in addressing this issue.
Constructing a Nomogram for Predicting Pelvic Osteosarcoma: A Retrospective Study Based on the SEER Database and a Chinese Cohort
Authors: Xu Yefeng , Yan Qingying , Yang Jiewen , Cheng Miao , Chen Jialu , Yao Yongwei , Liu Yunxia
Published: August 2024

Aims/Background Generally, pelvic osteosarcoma has a worse prognosis compared with limb osteosarcoma. This study aims to create and validate a new nomogram for predicting the prognosis of pelvic osteosarcoma.

Methods Clinical data of 62 patients derived from the Surveillance, Epidemiology, and End Results (SEER) database and 31 Chinese patients diagnosed with pelvic osteosarcoma were gathered. Kaplan-Meier survival analysis was utilized to calculate the median survival time for all variables. Univariate and multivariate Cox regression models were employed to identify the prognostic factors of pelvic osteosarcoma. A nomogram was constructed using data gleaned from the SEER cohort and verified using the receiver operating characteristic (ROC) curve and calibration plot in the Chinese cohort.

Results Kaplan-Meier analysis revealed that individuals of other races (Asians) (hazard ratio (HR) = 0.24, 95% confidence interval (CI): 0.1–0.57, p = 0.001), aged ≤51 years old (HR = 0.4, 95% CI: 0.22–0.73, p = 0.003), and with tumor size ≤160 mm (HR = 0.37, 95% CI: 0.2–0.71, p = 0.03) had better survival outcomes. Conversely, factors such as no primary surgery (HR = 3.6, 95% CI: 1.81–7.15, p < 0.001), lung metastasis (HR = 1.96, 95% CI: 1.17–3.28, p = 0.010), and radiotherapy (HR = 1.89, 95% CI: 1.10–3.25, p = 0.021) were associated with poorer survival. Multivariate Cox analysis indicated that lung metastasis (HR = 2.57, 95% CI: 1.29–5.13, p = 0.008), other races (Asians) (HR = 0.23, 95% CI: 0.07–0.75, p = 0.015), tumor size (HR = 0.28, 95% CI: 0.13–0.62, p = 0.001) and age (HR = 0.3, 95% CI: 0.16–0.59, p < 0.001) were independent prognostic factors for pelvic osteosarcoma. Univariate and multivariate Cox regression models identified three independent variables in the training cohort: age, lung metastasis, and tumor size. A predictive nomogram was developed based on the data from the SEER cohort and validated in the Chinese cohort. The areas under the curves (AUCs) that are used to predict 1-year, 2-year, and 3-year survival rates were 0.81 (95% CI: 0.68–0.94), 0.75 (95% CI: 0.63–0.86), and 0.80 (95% CI: 0.70–0.89) in the training cohort, and 0.67 (95% CI: 0.30–1.04), 0.66 (95% CI: 0.43–0.90) and 0.71 (95% CI: 0.50–0.93) in the validation cohort.

Conclusion The predictive nomogram constructed in this study facilitates accurate and effective prediction of the overall survival of patients with pelvic osteosarcoma and helps enhance the clinical decision-making process.
The Study on Verbal Fluency in Older Adults in Nonthaburi Province
Authors:   Sirindhorn National Medical Rehabilitation Institute, Nonthaburi Province, Thailand., Suttichujit Isara , Kripanan Nicha ,   Sirindhorn National Medical Rehabilitation Institute, Nonthaburi Province, Thailand, Ruamsuk Somjit ,   Sirindhorn National Medical Rehabilitation Institute, Nonthaburi Province, Thailand
Published: August 2024

Background: Verbal fluency assesses cognitive function in dementia and word retrieval in aphasia. However, the lack of data on verbal fluency among healthy older Thai individuals hinders comparisons with patient results. This is particularly concerning because older individuals are at higher risk for stroke and dementia. As Thailand has transitioned into an aging society, addressing this gap in data is essential. Objective: This study aims to examine verbal fluency in Thai individuals aged 60 and above, focusing on factors such as age, gender, and education level affecting word count. The goal is to update Thai data, provide more assessment options, and enhance understanding of related factors. This will improve the accuracy of result interpretation and inform treatment planning. Materials and methods: The study involved 147 healthy Thai individuals aged 60-89 living in Nonthaburi, Thailand. Participants must pass the Thai Mental State Examination (TMSE), visual screening by naming a picture and reading text, hearing screening through finger rubbing, oral reading (Noo Jaew Passage), and oral motor examinations to include only healthy participants without speech impairment. The speech-language pathologist, as an examiner, asks participants to generate words within a minute for each category (randomly assigned: animal, object, and food). Each intelligible and correct word in their category was scored. Researchers transcribed the recordings and counted the words produced. Results: The average age of the total participants was 70.59 (SD=7.25) years, with 110 women (75%). The average words are: 19.35 (SD=5.25) animals, 20.18 (SD=6.70) objects, and 15.02 (SD=4.56) foods. Participants aged 60-69 exhibited the highest verbal fluency for animal, object, and food categories at 20.63 (SD=5.02), 21.86 (SD=6.19), and 16.35 (SD=4.71), respectively. Conclusion: The study investigates verbal fluency in older Thai individuals in Nonthaburi, focusing on animal, object, and food categories. Results show that fluency declines with age. While higher education enhanced performance in the animal and object categories, it did not affect the food category. Gender significantly impacted the food category, with females performing better, possibly due to cultural roles. The data can be helpful in clinical assessments and future research on cognitive aging in Thai populations.
Anti-Russian Orthodox Discourses in the Trial of Anton Berezowski
Authors: Bailey Heather
Published: August 2024

ABSTRACT: In 1867 a Polish refugee in France, Anton Berezowski, tried to assassinate Emperor Alexander II when he visited Paris for the Great Exposition. Berezowski was tried for premeditated homicide and was defended by a prominent republican advocate who had a history of defending political crimes, Emmanuel Arago. In his pleading for the defense, Arago spun the attempted assassination as a political crime by invoking anti-Russian and anti-Orthodox motifs that had become commonplace in French public discourse. He portrayed Russia as the persecutor of martyred Poland, the tsar as the pope of the Russian Church and practically a self-proclaimed deity, and Berezowski's family as victims of tsarist religious persecution. Without legitimizing assassination, Arago used religious discourses to portray Berezowski as a misguided but devout Polish patriot. On the whole, Berezowski's trial represented a symbolic and moral trial of Russia in the court of public opinion for its treatment of Poland.
Techno-theologoumena and Rise of Far-Right Orthodox Internet Celebrities
Authors: Riccardi-Swartz Sarah
Published: August 2024

ABSTRACT: Eastern Orthodoxy possesses hierarchical theological and social structures that emphasize obedience to doctrinal teachings and, often, deference to the guidance of clergy and monastic elders. As a religious organization, Orthodoxy perpetually returns to the writings and teachings of the Church Fathers, ecumenical councils, and well-established theologians to make sense of contemporary social-moral issues in a synodal way. While each Eastern Orthodox jurisdiction possesses the same dogma, they also each have their own theologoumena (theological opinions), which have, in many cases, become emphasized within certain strands of Orthodox thought. Despite this flexibility, there has been a consistent understanding among canonically affiliated Orthodox communities of what counts as religious authority, where it comes from (mainly through revealed theology preserved via Church tradition), and how it should be considered and practiced. In our contemporary moment, however, Orthodox digital content creators are transforming the concepts of theological opinion and religious authority, often linking them together in the production of their overtly political content. Drawing on digital research, this article employs a critical media analysis of far-right Orthodox social media content to explore the digital expressions and transformation of religious authority and theological opinion. I argue that the affordances of digital modalities allow for these religious actors to become virtual micro-celebrities, building out branded, authoritative forms of what I term techno-theologoumena —digitally transmitted religious opinions—through their content and presence.
Imagined Nuns in a Real Convent in John Dryden’s The Assignation
Authors: Acosta Ana M.
Published: August 2024

Abstract: The convent in John Dryden’s The Assignation: Or, Love in a Nunnery (1673) is a space where numerous strains of patriarchal power intersect and are negotiated. The Assignation draws on a long tradition of theatrical plots involving convents to affirm in this particular play the value of a stable monarchy and the order it engenders. Dryden constructs a mixture of real and imagined situations for the women in the convent and provides a predictably secular resolution in the last act.
Small Things That Cleave: Hannah Allen’s Scissors and Her Religious Melancholy
Authors: Seymour Laura
Published: August 2024

Abstract: Content note: suicide, self-harm, domestic violence Hannah Allen’s Satan’s Methods and Malice Baffled is an extraordinary text from 1683 that details Allen’s experiences of self-harm and suicidal ideation. This article analyzes these themes by focusing on a small but significant object: Allen’s pair(s) of scissors, which she uses as instruments of self-injury and tools for communication. Placing Satan’s Methods within the context of emotional history, this article uncovers the rich religious meanings of Allen’s acts of self-wounding.
Feminine Duties and Happiness Deferred in Frances Sheridan’s Sidney Bidulph Novels
Authors: Blakely Kathryn
Published: August 2024

Abstract: This article explores how a reconsideration of what women owe and to whom necessitates a revision of narrative forms and narrative closure. It argues that Frances Sheridan extends her heroine’s happy ending—in this case, her death rather than marriage—onto a sequel to illustrate the persistence of Sidney’s commitment to other women as well as the incongruity of the marriage plot as a proper container for a woman’s lived experiences. By privileging duty over happiness, Sidney embodies a moral code that aspires to a Kantian ethic only available to men.
Introduction: Archive Memories
Authors: Barnden Sally
Published: August 2024

Abstract: This special issue draws attention to the place of archives in the study of early modern performance. The introduction establishes key concerns shared by the six articles, including the relationship between theorizations of the archive and its material reality, the politics of archival preservation, and unequal access to archival knowledge. It begins with reflections on the process of visiting the elaborately defended Royal Archives at Windsor Castle, using this anecdote as a provocation for questions about access, and as a starting point for broader questions about the relationship between ephemeral performance, memory, and documentary or material remnants.
"Of no consequence"? Rachel Fane's Manuscripts and Archival Erasure
Authors: Julian Erin
Published: August 2024

Abstract: This article explores the significance of Rachel Fane/Bourchier's archive as a source of information about seventeenth-century domestic performance. This archive remains underexplored due to Nathaniel Wraxall's interventions in the Sackville archives, which contributed to the neglect of Rachel's archive in the nineteenth and twentieth centuries. Wraxall's interventions serve as a departure point to explore archival absence and loss more broadly: reviewing archival trends in the latter half of the twentieth century, the article thinks through different kinds of absences in archival collections. While archival loss is inevitable, it affects those already marginalized within the archives unduly, in ways that early modern scholars must attend to carefully. Ultimately, this article concludes by considering the ways that Rachel herself contributed to archival erasure within her own records, calling attention to the ongoing duty of care historians owe to subjects who have been written out of dominant historical narratives.
"Deep River Did It": Fuenteovejuna , Harlem Suitcase Theater, and the Performative Potential of Archival Marginalia
Authors: Seremet Molly Beth
Published: August 2024

Abstract: This article witnesses a performance that only happened within the archive: a partial translation of Lope de Vega's Fuenteovejuna created by African American writer Dorothy Peterson during the Harlem Renaissance. She intended for Langston Hughes to take her literal translation and rework it poetically for Harlem Suitcase Theater. The project did not come to fruition because the theater folded in 1926. This performance that never happened lives within Hughes's collected papers, chronicled in the letters Peterson and Hughes exchanged about the project, as well as in Peterson's hand-notated blueprint for Hughes's never-completed adaptation. It crackles with archival potential energy, ready to resituate Lope's play within the context of the Harlem Renaissance. This article examines these archival traces, mining Peterson's nuanced interventions into Lope's text to innervate both the state of suspended animation of Peterson and Hughes's vision and the resonance this potential performative energy carries today.
Navigated ultrasound bronchoscopy with integrated positron emission tomography—A human feasibility study
Authors: Kildahl-Andersen Arne , Hofstad Erlend Fagertun , Solberg Ole-Vegard , Sorger Hanne , Amundsen Tore , Langø Thomas , Leira Håkon Olav
Published: August 2024

Background and objective

Patients suspected to have lung cancer, undergo endobronchial ultrasound bronchoscopy (EBUS) for the purpose of diagnosis and staging. For presumptive curable patients, the EBUS bronchoscopy is planned based on images and data from computed tomography (CT) images and positron emission tomography (PET). Our study aimed to evaluate the feasibility of a multimodal electromagnetic navigation platform for EBUS bronchoscopy, integrating ultrasound and segmented CT, and PET scan imaging data.

Methods

The proof-of-concept study included patients with suspected lung cancer and pathological mediastinal/hilar lymph nodes identified on both CT and PET scans. Images obtained from these two modalities were segmented to delineate target lymph nodes and then incorporated into the CustusX navigation platform. The EBUS bronchoscope was equipped with a sensor, calibrated, and affixed to a 3D printed click-on device positioned at the bronchoscope’s tip. Navigation accuracy was measured postoperatively using ultrasound recordings.

Results

The study enrolled three patients, all presenting with suspected mediastinal lymph node metastasis (N1-3). All PET-positive lymph nodes were displayed in the navigation platform during the EBUS procedures. In total, five distinct lymph nodes were sampled, yielding malignant cells from three nodes and lymphocytes from the remaining two. The median accuracy of the navigation system was 7.7 mm.

Conclusion

Our study introduces a feasible multimodal electromagnetic navigation platform that combines intraoperative ultrasound with preoperative segmented CT and PET imaging data for EBUS lymph node staging examinations. This innovative approach holds promise for enhancing the accuracy and effectiveness of EBUS procedures.
Causal association of menstrual reproductive factors on the risk of osteoarthritis: A univariate and multivariate Mendelian randomization study
Authors: Tan Xinzhe , Mei Yifang , Zhou Yihao , Liao Zhichao , Zhang Pengqi , Liu Yichang , Han Yixiao , Wang Dongyan
Published: August 2024

Objective

Several observational studies have revealed a potential relationship between menstrual reproductive factors (MRF) and osteoarthritis (OA). However, the precise causal relationship remains elusive. This study performed Mendelian randomization (MR) to provide deeper insights into this relationship.

Methods

Utilizing summary statistics of genome-wide association studies (GWAS), we conducted univariate MR to estimate 2 menstrual factors (Age at menarche, AAM; Age at menopause, AMP) and 5 reproductive factors (Age at first live birth, AFB; Age at last live birth, ALB; Number of live births, NLB; Age first had sexual intercourse, AFSI; Age started oral contraceptive pill, ASOC) on OA (overall OA, OOA; knee OA, KOA and hip OA, HOA). The sample size of MRF ranged from 123846 to 406457, and the OA sample size range from 393873 to 484598. Inverse variance weighted (IVW) method was used as the primary MR analysis methods, and MR Egger, weighted median was performed as supplements. Sensitivity analysis was employed to test for heterogeneity and horizontal pleiotropy. Finally, multivariable MR was utilized to adjust for the influence of BMI on OA.

Results

After conducting multiple tests (P<0.0023) and adjusting for BMI, MR analysis indicated that a lower AFB will increase the risk of OOA (odds ratio [OR] = 0.97, 95% confidence interval [CI]: 0.95–0.99, P = 3.39×10−4) and KOA (OR = 0.60, 95% CI: 0.47–0.78, P = 1.07×10−4). ALB (OR = 0.61, 95% CI: 0.45–0.84, P = 2.06×10−3) and Age AFSI (OR = 0.66, 95% CI: 0.53–0.82, P = 2.42×10−4) were negatively associated with KOA. In addition, our results showed that earlier AMP adversely affected HOA (OR = 1.12, 95% CI: 1.01–1.23, P = 0.033), and earlier ASOC promote the development of OOA (OR = 0.97, 95% CI: 0.95–1.00, P = 0.032) and KOA (OR = 0.58, 95% CI: 0.40–0.84, P = 4.49×10−3). ALB (OR = 0.98, 95% CI: 0.96–1.00, P = 0.030) and AFSI (OR = 0.98, 95% CI: 0.97–0.99, P = 2.66×10−3) also showed a negative association with OOA but they all did not pass multiple tests. The effects of AAM and NLB on OA were insignificant after BMI correction.

Conclusion

This research Certificates that Early AFB promotes the development of OOA, meanwhile early AFB, ALB, and AFSI are also risk factors of KOA. Reproductive factors, especially those related to birth, may have the greatest impact on KOA. It provides guidance for promoting women’s appropriate age fertility and strengthening perinatal care.
Natural dynamics and watershed approach incorporation in urban water management: A scoping review
Authors: Canteiro Marcelo , Cotler Helena , Mazari-Hiriart Marisa , Babinet Nadjeli , Maass Manuel
Published: August 2024

Several cities are facing water emergencies related to urbanization impact and amplified by climate change. Most of the cities have responded to these crises through short-term measures. However, some cities have incorporated a watershed approach to water management in seeking more sustainable solutions. Although the importance of a watershed approach in land management is generally acknowledged, studies on this topic have typically focused on theoretical models, water management in rural areas or single case-studies of cities or countries. In this research, a scoping review of the literature was performed, based on the PRISMA 2020 statement, in three databases: Web of Science, Google Scholar and SciELO. Forty-one studies were identified analyzing 17 city cases implementing urban actions from a watershed approach in water management. These cities were from the Global North and Asian rising world powers. The lack of results of cities from the Global South, based on the research undertaken, was the main limitation and bias identified. Most of the Global South results identified in this research were theoretical models, scenarios and cases of rural areas instead of urban contexts. The results obtained indicate that the main motivations for cities to implement a watershed approach were water scarcity, floods and contamination of water bodies. The implemented actions focused on the shift from gray to green and blue infrastructure and on conservation measures. Lastly, the challenges to introduce those actions were mainly the lack of economic investment, insufficient experience, stakeholder opposition, and regulatory obstacles. Urban water management could be seen as an opportunity to change the way we relate to urban territory. Incorporating a watershed approach into urban planning and water management could promote more sustainable cities.
Childhood trauma, PTSD/CPTSD and chronic pain: A systematic review
Authors: Karimov-Zwienenberg Maria , Symphor Wilfried , Peraud William , Décamps Greg
Published: August 2024

Background

Despite the growing body of literature on posttraumatic stress disorder (PTSD) and chronic pain comorbidity, studies taking into account the role of childhood exposure to traumatic and adverse events remains minimal. Additionally, it has been well established that survivors of childhood trauma may develop more complex reactions that extend beyond those observed in PTSD, typically categorized as complex trauma or CPTSD. Given the recent introduction of CPTSD within diagnostic nomenclature, the aim of the present study is to describe associations between childhood trauma in relation to PTSD/CPTSD and pain outcomes in adults with chronic pain.

Methods

Following PRSIMA guidelines, a systematic review was performed using the databases Pubmed, PsychInfo, Psychology and Behavioral Sciences Collection, and Web of Science. Articles in English or French that reported on childhood trauma, PTSD/CPTSD and pain outcomes in individuals with chronic pain were included. Titles and abstracts were screened by two authors independently and full texts were consequently evaluated and assessed on methodological quality using JBI checklist tools. Study design and sample characteristics, childhood trauma, PTSD/CPTSD, pain outcomes as well as author’s recommendations for scientific research and clinical practice were extracted for analyses.

Results

Of the initial 295 search records, 13 studies were included in this review. Only four studies explicitly assessed links between trauma factors and pain symptoms in individuals with chronic pain. Findings highlight the long-term and complex impact of cumulative childhood maltreatment (e.g., abuse and neglect) on both PTSD/CPTSD and chronic pain outcomes in adulthood.

Conclusion

This review contributes to current conceptual models of PTSD and chronic pain comorbidity, while adding to the role of childhood trauma and CPTSD. The need for clinical and translational pain research is emphasized to further support specialized PTSD/CPTSD treatment as well as trauma-informed pain management in routine care.
Geochemical characteristics and detrital zircon U-Pb ages of the Yimin Formation, Kelulun Depression, Hailar Basin and constraints on uranium mineralization
Authors: Meng Fanmin , Nie Fengjun , Xia Fei , Yan Zhaobin , Sun Da , Zhou Wenbo , Zhang Xin , Wang Qing
Published: August 2024

The sandstone uranium deposits in the Kelulun Depression are the first commercially viable uranium deposits discovered in the Hailar Basin and the ore-bearing strata corresponding to the Lower Cretaceous Yimin Formation. However, the source of sedimentary matter, uranium source conditions, and uranium mineralization processes in the region have not been characterized. Accordingly, we analyzed the lithology, whole-rock geochemistry, zircon U-Pb ages, and trace elements of the Yimin Formation sandstones. The Yimin Formation sandstones were primarily composed of detrital grains with low compositional maturity. A geochemical analysis indicated that the parent rocks are felsic igneous rocks formed at an active continental margin with a moderately high degree of weathering. The detrital zircon U-Pb ages of the Yimin Formation 215–287 Ma with a peak at 230–260 Ma. Based on chronological, geochemical, and lithological data, we conclude that the Yimin Formation matter is derived from the Adunchulu Uplift on the western side of the Kelulun Depression and its parent rocks are Triassic granites. The Adunchulu uplift since the late Early Cretaceous and weathering and denudation of its uranium-rich granites provided ample matter and uranium. Therefore, the Kelulun Depression is a promising area for the exploration of sandstone uranium deposits.
Vocational identity in decision-making for terminating/continuation of pregnancy following non-invasive prenatal testing and hypothetical diagnosis among Japanese university students
Authors: Sunagozaka Shodai , Tsutsumi Atsuro
Published: August 2024

The use of prenatal testing in Japan is expected to increase. However, there are ethical concerns regarding pregnancy termination upon the detection of fetal chromosomal abnormalities, such as Down syndrome. Furthermore, factors associated with decision-making following a positive result of Down syndrome after prenatal screening remain unclear. Therefore, we aimed to evaluate the association between decision-making among university students following a hypothetical positive result of Down syndrome in prenatal screening and their perception of their future career development defined as vocational identity. This cross-sectional study included 256 individuals (109 men, 143 women, and four who preferred not to answer). Self-anonymous semi-structured questionnaires were distributed to collect information regarding socio-demographic characteristics, vocational identity, and decision-making following a positive prenatal screening result of Down syndrome. Vocational identity was assessed using the Vocational Identity Measure. Women students were more likely to intend to continue the pregnancy (76.9%, p < 0.05); however, students without siblings (68.2%, p < 0.01) and men and women students with higher scores for vocational identities who were raised in an academically oriented family were more likely to intend to terminate the pregnancy (p < 0.05). Therefore, gender and vocational identity were associated with decision-making following a positive result of Down syndrome. Further qualitative and quantitative studies on factors associated with decision-making following a positive result of Down syndrome are necessary to eliminate the burden and social barrier, including gender division of labor and the effect of vocational career for people wishing to parent a child with Down syndrome.
Survivin inhibition attenuates EGF-induced epithelial mesenchymal transformation of human RPE cells via the EGFR/MAPK pathway
Authors: Zhu Yusheng , Li Teng , Zhou Sirui , Wang Guowei , Zhang Huihui , Yin Yong , Wang Tong , Chen Xiaodong
Published: August 2024

Purpose

The abnormal growth factors–induced epithelial-mesenchymal transition (EMT) in retinal pigment epithelial (RPE) cells was known as a vital pathogenesis of proliferative vitreoretinopathy (PVR). This study aims to explore how survivin inhibition affects EMT induced by epidermal growth factor (EGF) in RPE cells.

Methods

Human primary RPE cells were identified in vitro. EMT in RPE cells was induced by EGF. Inhibition of survivin in RPE cells was accomplished through the use of a survivin inhibitor (YM155) and survivin siRNA. The viability, proliferation and migration of RPE cells was detected by methylthiazol tetrazolium assay, bromodeoxyuridine labeling assay, and wound healing assay, respectively. The EGF receptor /mitogen–activated protein kinase (EGFR/MAPK) proteins and EMT-related proteins were measured by western blot and immunofluorescence assay.

Results

EGF induced significant EMT in RPE cells, activated the phosphorylation of EGFR/MAPK signaling proteins, and caused changes to EMT-related proteins. YM155 suppressed RPE cells’ viability, proliferation, and migration; induced the phosphorylation of EGFR, JNK, and P38MAPK; and down regulated EGFR and phosphorylated ERK. YM155 also increased expression of E-cadherin and ZO-1 proteins and reduced expression of N-cadherin, Vimentin, and α-SMA proteins. The EGF-induced increase of RPE cell proliferation and migration was constrained by survivin inhibition. Moreover, survivin inhibition in RPE cells suppressed the EGF-caused phosphorylation of EGFR/MAPK proteins and attenuated the EGF-induced reduction of E-cadherin and ZO-1 proteins and increase of N-cadherin, Vimentin, and α-SMA proteins.

Conclusions

Survivin inhibition attenuates EGF-induced EMT of RPE cells by affecting the EGFR/MAPK signaling pathway. Survivin might be a promising target for preventing PVR.
Catheter-associated urinary tract infections in critical care: Understanding incidence, risk factors, and pathogenic causes in Palestine
Authors: Rabi Razan , Enaya Ahmad , Jomaa Dana Mufeed , Dweekat Mo’tasem Z. , Raddad Shahd , Saqfalhait Zain Tareq , Abu-Gaber Dina
Published: August 2024

Catheter-associated urinary tract infections (CAUTI) are the most common secondary cause of bloodstream infection. CAUTI is particularly prevalent in critical care departments and developing countries, where the duration of catheterization remains the most significant risk factor. This study focused on the characteristics, risk factors, and outcomes of CAUTI patients in a tertiary care hospital setting. It also provides the incidence rate of CAUTI in an ICU setting in Palestine. The study adopted a retrospective observational design at a tertiary care hospital in Palestine. The data were collected from patient records as well as from nursing flow charts. Variables are reported as frequencies, percentages and means + standard deviations. Independent t-tests was used for numerical variables, while Pearson’s chi-square or Fisher’s exact test were used for categorical variables. Multivariate analysis was performed to adjust for confounders using binary logistic regression. Mortality risk factors were assessed using the proportional Cox regression model. Of the 377 patients included in the study, 33 (9%) developed CAUTI. Among CAUTI patients, 75% had Candida species isolated, with non-albicans Candida predominating (72%) fungal isolates. On the other hand, 25% of the patients had bacterial isolates in their urine, with a predominance of Escherichia coli growing in 36% of bacterial cultures. Multivariate regression analysis revealed that female gender, longer catheterization days, and corticosteroid use were associated with an increased risk of CAUTI. On the other hand, developing CAUTI, having a malignant disease, developing kidney injury, and developing shock were associated with increased mortality. This study highlighted the emerging presence of fungal and resistant bacterial CAUTI. It also emphasized that the risk of CAUTI was associated with a longer duration of urinary catheterization. The findings of this study may help formulate antimicrobial management and stewardship plans as well as emphasize the risk of urinary catheterizations.
Curating the Supernatural
Authors: Cozzolino Robert
Published: August 2024

Supernatural America: The Paranormal in American Art opened in June 2021, amidst the COVID-19 pandemic and reverberations from racial justice uprisings in 2020. The exhibition took shape over five years, growing and deepening through collaborative practices with several different communities, including Spiritualists. Partnerships with paranormal experiencers and practitioners, as well as sceptics and academics across the humanities, enhanced the exhibition’s curatorial and interpretive framework. Artworks made by trance mediums in ritual settings played a key role in the project and were integrated into a broad context of paranormal visual and material culture. These sacred artefacts, borrowed from Spiritualist camps, had never before left their communities. This curatorial reflection describes the relational approach to curating that prepared me to respond to ethical concerns, informed the interpretive plan and led to a sensitive presentation of this content.
Arts-Based Interventions and Social Change in Europe, Andrea Kárpáti (ed.)
Authors: Southcott Olivia
Published: August 2024

Review of: Arts-Based Interventions and Social Change in Europe, Andrea Kárpáti (ed.)

New York: Routledge (2024), 254 pp., h/bk,

ISBN: 978-1-0324-4151-1, US$180.00
AI in Museums: Reflections, Perspectives and Applications, Sonja Theil and Johannes C. Bernhardt (eds)
Authors: Lopes Catherine
Published: August 2024

Review of: AI in Museums: Reflections, Perspectives and Applications, Sonja Theil and Johannes C. Bernhardt (eds)

Bielefeld: Transcript (2024), 320 pp., p/bk,

ISBN: 978-3-8376-6710-3, €39.00; PDF, ISBN: 978-3-8394-6710-7
Extraction of Nanocellulose Fiber from Agrowastes for Efficient Fluoride Removal: A Sustainable Approach
Authors: Gatawa G. , Nahurira J. , Gamaniel L. , Mayani V. , Thaker R. , Mayani S.
Published: August 2024

The subject of water defluorination is becoming increasingly important, owing to chronic diseases such as fluorosis, neurological impairment and bone softening caused by fluoride contamination of drinking water in excess of 1.5 mg L–1. Agrowastes (cotton seed and groundnut shells), the commonly available and renewable resource, were used as the precursor for the production of nanocellulose fiber i.e. cotton seed nanocellulose fiber (CNF) and groundnut shell nanocellulose fiber (GNF) as an exceptional method for fluoride removal. The physico-chemical characterization techniques were employed to analyze the structure and morphology of the synthesized nanocellulose fibre. To optimize the adsorption process, the impacts of several parameters including pH, contact time and adsorbent dosage were evaluated. The maximum amount of fluoride that could be removed under ideal conditions was investigated using a UV-visible spectrophotometry and was found to be 90%. This approach offers several advantages such as low-cost raw materials, eco-friendly synthesis methods and a high-performance adsorbent.
Corrosion Inhibition of Mild Steel in Hydrochloric Acid Solution using Methanolic Extracts of Elsholtzia communis and Spilanthes acmella as Green Inhibitors
Authors: Rajan Jay Prakash
Published: August 2024

The corrosion inhibition effect of methanolic extract of Elsholtzia communis inflorescence (ECI) and Spilanthes acmella (SA) towards the corrosion of mild steel in 1 N HCl solution was examined by means of weight loss, potentiodynamic polarization and electrochemical impedance spectroscopy (EIS) techniques. The corrosion rate was found to decrease with increasing ECI and SA concentration up to 0.5 g/L at 27 ºC. The temperature effect on inhibition effect of plant extracts has also been discussed. Nyquist plots showed that methanolic extract of ECI yielded the best inhibition efficiency. The adsorption of inhibitor on the mild steel surface was found to obey the Langmuir adsorption isotherm through which various thermodynamic parameters were calculated and discussed. Surface morphology of the mild steel after exposing to test solutions in absence and presence of inhibitor were investigated by scanning electron microscope (SEM), which show that the corrosion of mild steel is retarded to great extent by ECI and SA extracts. The phytochemicals screening were performed by gas chromatography-mass spectroscopy (GC-MS) study based on this study effective inhibitor molecules and inhibitive mechanism can be established. The GC-MS and FT-IR studies of ECI and SA extracts indicated that the adsorption centre in green inhibitor probably due to presence of β-retinoid and its derivatives in ECI and SA extracts showed that the adsorption centre due to presence of fatty acid derivatives.
Structural and Photoluminescence Characteristics of Dy3+ Doped Zn2SiO4 Phosphors for White Light Emitting Diodes
Authors: Sinha Akash , Jena V. , Verma B. , Tiwari Kanchan
Published: August 2024

Silicate-based Zn2SiO4 phosphor was synthesized by a low-cost solid-state reaction method doped with varying concentrations of Dy3+ ion (1, 2, 4, 6, 8 & 10% mol). The powder X-ray diffraction results revealed that the crystal structure of the synthesized phosphor was orthorhombic, which was matched with ICCD No. 00-037-1485. The average crystallite size of Zn2SiO4: Dy3+ was determined using the Debye-Scherrer formula and the W-H plot was found to be -32 nm and -41 nm, respectively. Field emission electron microscopic study showed the surface morphology of the synthesized phosphor was irregular in shape with slight tendency of agglomeration. The photoluminescence emission spectra of the phosphor exhibited intense emission spectra at 464, 488 and 579 nm, 4H15/2→6I15/2, 4F9/2→6H15/2, 4H9/2→6H13/2 of Dy3+ ions, respectively when excited at 337 nm and their corresponding colour coordinates and correlated colour temperatures were also calculated.