bluuebunny/crossref_metadata_2025 huggingface dataset:
An Audit of Histopathology Reports of Invasive Breast Carcinomas with Reference to Adequacy and Amendments
Authors: Liza Victoria , Ravikumar Gayatri , Tirumalae Rajalakshmi
Published: December 2022

Background: Periodic auditing of histopathology report (HPR) of breast cancer, monitors compliance and increases the standards of reporting. This study was done to audit the completeness of breast cancer HPR in accordance with the CAP protocol and to analyse the amendments in tumour summaries. Methods: Retrospective review of HPR of invasive breast carcinoma resections from 2016-2020. Core (CE) and non-core elements (NCE) evaluated using CAP protocols. Outcome measures analyzed: (i) overall report completeness for CE (ii) element specific completeness for all reports. Amendments were reviewed. Results: Breast cancer reports included 246 resections. Most common histological variant was ductal type, NOS. Overall completeness was seen in 87%. Biomarker status was available in 83.1%. Reporting format was synoptic-like structured format. CAP protocol underwent five revisions between 2016-2019 with shifting of parameters between CE and NCE. Adequately represented CE: procedure, tumour size & type, Nottingham score, grade, stage, DCIS, margin status, lymph nodes and lymphovascular invasion. Less commonly reported CE: laterality, extent of involvement, size of largest metastatic deposit and extranodal extension. Frequently reported NCE: LVI, architecture/grade of DCIS, findings in adjacent breast. Biomarker reporting and treatment effect was complete in all reports. Amended reports were 4.8%. Majority were transcriptional errors. Conclusion: Common CE were satisfactorily represented in majority. Reasons for deficiencies were frequent change in CAP protocols and flexibility in synoptic-like structured format over synoptic format. The study underscores the need for periodic auditing of breast cancer summaries to monitor gaps in CE reporting. Synoptic reporting with additional free text field will improve compliance and overcome deficiencies.
Malignant Melanoma of the Palate: Report of a Metastatic Case
Authors: B. Cruz-Ordinario Mel Valerie , Dg. Boado Carlo Antonio , Gorospe Agnes E
Published: December 2022

Primary malignant melanoma of the oral cavity is a rare malignancy with an incidence of 0.2 to 8% of all melanomas. Melanoma arises from the malignant transformation of the melanocyte and cutaneous melanomas are the most common followed by ocular, mucosal and melanoma of unknown primary site. Here we present a case of a 54 year old male who presented with a pigmented lesion on the palate, a type of mucosal melanoma. Due to the rarity of this disease, it is infrequently studied. Hence, epidemiology, etiology, pathogenesis and prognosis still remains to be less understood than cutaneous melanoma. Early diagnosis is warranted as therapeutic options are limited for advanced and metastatic disease. Surgery is the primary therapeutic management and complete resection is the main goal. If not feasible, radiotherapy may also be employed to achieve local control and enhance locoregional response. Prognosis is generally poor for metastatic disease and there are no guidelines yet on the use of systemic therapy.
Karşıt Tabanlı Öğrenme İle Geliştirilmiş Yapay Denizanası Arama Algoritması
Authors: YILDIZDAN Gülnur
Published: December 2022

Bu çalışmada denizanalarının okyanustaki yiyecek arama davranışının modellenmesi ile oluşturulan yapay denizanası arama algoritmasının (JS) performansını geliştirmek amacıyla yeni gelişmiş bir algoritma önerilmiştir. Bunun için JS’ye karşıt tabanlı öğrenme yaklaşımı dahil edilerek popülasyondaki bireylerin arama uzayına daha doğru şekilde dağıtılması sağlanmıştır. Geliştirilmiş algoritma(KJS), standart kıyaslama fonksiyonları üzerinde 10,30,50,100,500 ve 1000 boyut için test edilmiştir. Elde edilen sonuçlar JS ve literatürdeki algoritmalarla karşılaştırılmış, istatistik testler ile yorumlanmıştır. Sonuçlar değerlendirildiğinde önerilen KJS algoritmasının başarılı ve kabul edilebilir sonuçlar ürettiği tespit edilmiştir.
Makine Öğrenmesi Tabanlı Mikrodizi Tekniği ile MikroRNA Hedef Tahmini: Araştırma Çalışması
Authors: YILDIZ ÇAVDAR Zerrin , ENSARİ Tolga , TURKER SENER Leyla , SERTBAŞ Ahmet
Published: December 2022

Biyoenformatik, biyolojik bilgilerin bilgisayar teknolojileri yardımıyla incelenmesini ve değerlendirilmesini sağlayan bir araştırma alanıdır. Çok disiplinli bu alan sayesinde tıbbi veriler üzerinde yapılan çalışmalarda hızla yol alınabilmekte, gerek hastalıkların teşhis-tedavi süreçlerinde gerek önlenmesi süreçlerinde başarılı çözümler bulunabilmektedir.

Birçok farklı organizmada görülen ve hücre üzerinde olaylarda etkili olduğu ortaya çıkan mikroRNA (miRNA, miR olarak da isimlendirilir, mikro RiboNükleik Asit’in kısaltmasıdır)’ların genler üzerindeki etkisi ile ilgili çalışmalar da biyoenformatik yöntemler yardımıyla başarılı sonuçlar vermektedir. Özellikle kanser ile yakın ilişkili olduğu düşünülen mikroRNA’ların incelenmesinde mikrodizi teknikleri sıklıkla tercih edilmektedir. Mikrodizi olarak hazırlanan veri setleri makine öğrenmesi yöntemleri ile değerlendirilerek mikroRNA hedef genlerinin belirlenmesi, mikroRNA’ya bağlı hastalık/kanserin teşhis ve tedavi süreçleri ile ilgili hızlı ve doğruluğu yüksek sonuçlar elde edilebilmektedir.

Bu araştırma çalışmasında, mikroRNA hedef gen tahmini sürecinde makine öğrenmesi tekniklerinin kullanımı incelenmiştir.
Videolardan Kalp Atış Hızı Kestirimi Üzerine Bir İnceleme
Authors: KORKMAZ Mustafa , VATANSEVER Saffet
Published: December 2022

Kalp atış hızı; kişinin sağlığı, aktivite seviyesi, stres durumu, zindeliği ve benzeri fizyolojik durumları hakkında önemli ipuçları vermektedir. Kalp atış hızı, elektrokardiyogram (EKG) ve nabız oksimetreleriyle ölçülebilir olmakla birlikte, bu cihazlar sürekli temas gerektirdiğinden zamanla rahatsız edici olabilmektedir. Bilgisayarlı görü (computer vision) alanındaki son gelişmeler, bir kişiye elektrot veya nabız oksimetreleri takmanın mümkün veya uygun olmadığı durumlarda, videolardan kişinin kalp atış hızını tespit etmeye olanak sağlamıştır. Uzaktan fotopletismografi (rPPG), bir video kamera aracılığıyla derideki hassas renk değişikliklerini yakalayarak, yaşamsal belirtilerin tespit edilmesine imkân sağlayan bir teknolojidir. Son yıllarda yapılan çalışmalar, uzaktan kalp atış hızı tespiti için en uygun bölgenin yüz olduğunu göstermiştir. Bu çalışmada; videolar aracılığıyla kişilerin yüz bölgesinden kalp atışı hızı kestiriminin nasıl yapılabildiği, kalp atışı hızı kestirimi sürecindeki aşamaların nasıl iyileştirilebileceği ve nasıl daha yüksek doğrulukta kalp atışı hızı tespiti yapılabileceği hakkında literatürdeki mevcut yöntemler incelenerek kapsamlı bir analiz yapılmıştır.
Design and Simulation of a PID Neural Network Controller for PMDC Motor Speed and Position Control
Authors: SHEIKH DEBES Rahaf , KARA Tolgay
Published: December 2022

Direct current (DC) motors have many difficulties when controlling angular velocity in a variety of applications. The perfect controller cannot be carried out by traditional control alone due to the nonlinear properties of DC motors, design constraints, and mechanical variations caused by the operation conditions. This study proposes a design for an artificial neural network based PID controller (ANNPID) to control the speed of a permanent magnet DC motor (PMDC) in two methods. A detailed analysis is performed based on the simulation results of both methods. The proposed controllers are numerically simulated for various test conditions including; set-point changes, step changes in the load torque, and parameter variations, then the suggested techniques were compared in a comparative study with a traditional PID controller based on the transient response specifications and the performance indices to validate the performance of the controllers. The simulation results demonstrated that the controllers have improved dynamics, static performance, and less overshoot. The methods described here achieve control more effectively than the conventional control approaches under both nominal and disturbed test conditions over different operating ranges.
The Effect of Different Amounts of Olive Oil on Sensory Properties of Ciabatta Bread
Authors: GÜMÜŞ Pınar
Published: December 2022

Ciabatta is a classic Italian bread type that has become popular around the world in recent years. It is characterized by crisp crust, large and irregular crumb grain. The objective of this study was to evaluate the effect of the use of different amounts of olive oil on the sensory properties of ciabatta bread samples. To determine the best mixture of bread, different amounts of olive oil were used to produce ciabatta bread. The sensory properties of three different kinds of bread (type I, type II, type III) were investigated such as shape and symmetry, crust color and crumb color, stickiness, mouthfeel, taste and aroma and overall assessment. Ash, moisture and protein content were also analyzed. In this study, when the sensory properties of the ciabatta breads were examined, it was observed that the effects of different amounts of olive oil on shape and symmetry, crust color and crumb color, stickiness, mouthfeel, taste and aroma and overall assessment of all ciabatta breads were not found statistically important (p>0.05). It was also found that ash and protein content was not significantly affected (p>0.05).
Investigation of Some Bioactivities and Odor Components of Jasminum officinale Linn. (Oleaceae): A Valuable Tool for Cosmetic Product Design
Authors: DEMİR Nazan , DALGIÇ Sedef , KAPLAN Alevcan
Published: December 2022

In this study, researches were carried out on the protease enzyme activity of Jasminum officinale Linn. flower which grows naturally in Muğla and its surroundings. In addition, fragrance components in the content of jasmine flower were determined. It was aimed to be used in perfume making based on the harmony of white jasmine flower with other flowers and the concept of note. Protease enzyme was purified from J. officinale flower using TPP (Three Phase Partitioning) method. Optimal pH and optimal temperature for the enzyme, Km and Vmax values for casein, azokazaein, gelatin, hemoglobin, and azoalbumin substrates were determined. SDS-PAGE was used to check the purity of the protease enzyme purified from the J. officinale. The molecular weight of the enzyme was calculated as 21.386 kDa using gel filtration chromatography. The phenolic content was also determined. It has been determined that the content of jasmine flower can be used in perfume design which is the most prestigious product of the cosmetic industry.
IMPLEMENTASI PROGRAM BANTUAN LANGSUNG TUNAI (BLT) BAGI MASYARAKAT MISKIN DI KABUPATEN MAJENE
Authors: Kusmin Achmad Fauzi , Taufiq Muhammad Syihabuddin , Rahmatullah
Published: December 2022

Objek penelitian ini adalah implementasi program Bantuan Langsung Tunai (BLT) di Kabupaten Majene. Penelitian ini bertujuan untuk mengetahui ketepatan implementasi program bantuan langsung tunai di kabupaten Majene berdasarkan berbagai aspek menurut teori implementasi kebijakan Van Meter dan Van Horn. Metode yang digunakan dalam penelitian ini adalah metode penelitian deskriptif dengan pendekatan kualitatif untuk menganalisis implementasi program bantuan langsung tunai di kabupaten Majene. Penulis mengumpulkan berbagai data mengenai program BLT yang dilakukan melalui kajian pustaka dan wawancara dengan masyarakat dan aparatur desa setempat. Informan dalam penelitian ini adalah 5 orang dari desa Buttu Baruga Kecamatan Banggae Timur dan di Desa Tinambung Kecamatan Pamboang. Penetapan sampel dilakukan dengan menggunakan metode unit analisis. Hasil penelitian menunjukkan bahwa implementasi program bantuan langsung tunai bagi masyarakat miskin di Kabupaten Majene telah terimplementasi dengan cukup baik. Hal ini dapat dilihat dari berbagai aspek pengukur, diantaranya adalah aspek standar dan sasaran kebijakan,  sumberdaya, karakteristik badan pelaksana, dan disposisi implementor. Setiap aspek memiliki berbagai indikator yang menentukan terpenuhi atau tidaknya suatu aspek.
STRATEGI INCUMBENT DALAM PEMENANGAN PEMILIHAN LEGILSLATIF
Authors: Nasiruddin Nurfadilah , Mausili Dwi Rianisa , Nuraliah Dewi
Published: December 2022

Tujuan Penelitian ini menganalisis strategi incumbent dalam Pemenangan Pemilihan Legislatif. Metode Penelitian menggunakan metode kualitatif, data dikumpulkan dari hasil observasi secara langsung, wawancara secara langsung dan mendalam. Tipe penelitian ini yakni deskriptif analisis. Teknik analisis data kualitatif dilakukan secara interaktif dan berlangsung secara terus menerus sampai tuntas. Aktivitas dalam analisis data yaitu pengumpulan data (data collection), reduksi data (data reduction), penyajian data (data display), dan pengecekan keabsahan data serta penarikan kesimpulan (data conclusion drawing/verification).

              Hasil dari penelitian ini yakni komunikasi yang intesn dengan masyarakat, bukan saja pada saat akan pemilihan tetapi jauh sebelum pemilihan akan dimulai, selain komunikasi incumbent juga memiliki pendekatan kekeluargaan yang kesemuanya dapat dibagai dengan tiga pendekatan. Pertama, menggalang loyalitas pemilih sehingga calon legislatif memiliki pemilih yang tetap pada setiap pemilihan. Kedua, menjalin komunikas yang harmonis dengan organisasi masyarakat (kelompok populis tertentu )untuk memberikan dukungan dan bantuan. Ketiga, bagi incumbent yang masih duduk di parlemen, memperkuat kebijakan yang berorientasi pada masyarakat.

              Penelitian ini, memiliki keterbatasan yakni hanya membatasi strategi yang dilakukan incumbent pada satu partai sehingga kedepannya peneliti menyerankan untuk meneliti berbagai strategi dari partai lain sehingga memberikan pemahaman dan pengetahuan yang lebih luas lagi.
I IMPLEMENTASI KEBIJAKAN BANTUAN LANGSUNG TUNAI (BLT) DANA DESA DI DESA JIPANG KECAMATAN BONTONOMPO SELATAN KABUPATEN GOWA
Authors: Ady Hermawansyah  , Purna Zarni Adia , Sugito Ahmad
Published: December 2022

Pandemi Covid-19 adalah penyakit yang disebkan oleh virus corona. Covid 19 tidak hanya berdampak pada kesehatan, tetapi juga berdampak pada ekonomi masyarakat. Untuk mengurangi dampak ekonomi, pemerintah membuat kebijakan Bantuan Langsung Tunai (BLT) Dana Desa. Desa Jipang Kecamatan Bontonompo Kabupaten Takalar adalah salah satu desa di Indonesia yang menyelenggarakan BLT Dana Desa. Ada beberapa kendala yang dihadapi pada saat pengimplementasian kebijakan seperti dalam pengimputan data, misalnya data yang di input merupakan data yang belum diperbaharui. Sehingga terjadi kesalahan seperti terdapat beberapa nama yang menerima bantuan selain (BLT dana desa). Tujuan dari penelitian ini yaitu untuk mengetahui implementasi kebijakan bantuan langsung tunai dana desa Di Desa Jipang Kecamatan Bontonompo Selatan Kabupaten Gowa dan untuk mengetahui faktor penghambat implementasi kebijakan bantuan langsung tunai di Desa Jipang Kecamatan Bontonompo Selatan Kabupaten Gowa. Metode penelitian yang digunakan peneliti yaitu metode penelitian kualitatif. Teknik Pengumpulan data yang digunakan oleh peneliti yaitu wawancara, observasi, dan dokumentasi. Metode tersebut digunakan untuk menjawab rumusan masalah dan hasilnya menjelaskan bahwa Bantuan langsung tunai di Desa Jipang selama proses bantuan langsung tunai berlangsung tidak berjalan sebagai mana mestinya atau kurang optimal, hal ini terbukti dari faktor-faktor implementasi kebijakan yaitu struktur birokrasi, sumber daya, komunikasi, dan disposisi
IMPLEMENTASI E-PROCUREMENT PADA DINAS PEKERJAAN UMUM KOTA MAKASSAR
Authors: Nurman sahar Nurman sahar , Sari R Syahfitri
Published: December 2022

E-procurement ialah sistem pengadaan barang dan jasa yang menggunakan teknologi berbasis website yang seluruh penyelenggaraannya dilakukan di sistem tersebut. Setelah Peneliti melakukan observasi awal Peneliti menemukan bahwa masih kurang pengetahuan pengguna jasa untuk menganalisis ketersediaan kuota, dan masih kurang sosialisasi dari pihak penyedia barang dan jasa hingga banyak sekali calon user dan masyarakat yang memberi komentar negatif mengenai layanan pengadaan barang dan jasa secara elektronik, masih kurangnya SDM untuk pengelola aplikasi e-procurement, masih kurangnya pejabat pengadaan karena tidak adanya perekrutan semenjak beberapa tahun belakang. Maka dari itu, Peneliti tertarik untuk meneliti lebih lanjut pelaksanaan pengadaan barang dan jasa secara e-procurement dengan judul “Implementasi E-Procurement Pada Dinas Pekerjaan Umum Kota Makassar”. Metode Penelitian yang digunakan pada penelitian ini ialah metode deskriptif kualitatif dengan 5 Informan yang berkaitan langsung dengan fokus penelitian berdasarkan fakta-fakta dari lapangan langsung dan berusaha menganalisis kebenarannya melalui hasil wawancara yang didapatkan untuk menentukan cara mencari, mengumpulkan mengolah dan menganlisis data tersebut. Teknik pengumpulan informasi yang dilakukan penulis yaitu dengan cara menyusun pertanyaan-pertanyaan yang akan diajukan pada informan melalui pratinjau dari 7 prinsip pengadaan barang dan jasa. Hasil penelitian dari judul penelitian Implementasi E-procurement Pada Dinas Pekerjaan Umum Kota Makassar yaitu Impelementasi e-procurement itu sendiri sudah dilakukan dengan baik dan sesuai aturan karena setelah aturan itu terbit maka seluruh SKPD yang terkait wajib untuk menjalankan aturan tersebut meskipun terpaksa, E-procurement juga telah mencapai tujuannya yaitu mengurangi KKN, membantu berjalannya pelaksanaan pengadaan barang dan jasa seperti prinsip efisien dan efektif, juga sudah terlaksananya prinsip transparan, terbuka, bersaing dan adil
DETEKSI DINI POTENSI ANCAMAN DARI TRANSFORMASI ORGANISASI RADIKAL PADA MASYARAKAT SULAWESI BARAT
Authors: Fita Gia Ayu , Saputra Aco Nata , Mulky Muhammad Alif
Published: December 2022

Gerakan-gerakan perubahan yang muncul dan disertai kekerasan dan merugikan masyarakat, biasanya disebut gerakan radikal atau ciri dari perbuatan radikalisme. Kebanyakan kegiatan radikal yang terjadi semata-mata ingin mengubah suatu sistem atau tatanan pemerintahan dengan suatu sistem yang dimana memasukkan pemahaman suatu agama. Dimana menurutnya, agamanya adalah yang paling benar dan paling sesuai. Radikalisme sendiri adalah sikap yang mengarah ke aksi terorisme. Jika ditelusuri lebih lanjut, kegiatan ini tidak berdasarkan agama atau mereka tidak memiliki agama, walaupun seolah-olah mengklaim dari agama tertentu dan mengatasnamakan salah satu agama. Misalnya Islam, agar mendapatkan simpati dari beberapa masyarakat Muslim dunia untuk berbagai bentuk dukungan terhadap aksi mereka. Di Indonesia sendiri, pasca pembubaran ormas-ormas yang bertemakan Islam di tahun 2020, malah ditengarai akan menimbulkan banyak kombatan-kombatan kecil di tengah masyarakat. Bagi peneliti ini sangat mengkhawatirkan, karena hal tersebut menimbulkan ancaman bagi stabilitas nasional yang mengarah konflik internal bahkan eksternal. Selanjutnya, peneliti akan melihat beberapa pola yang ada, khususnya di provinsi Sulawesi Barat. Dimana masyarakatnya menganut Islam Nusantara atau NU tradisional, tetapi bibit-bibit radikalisme pasca pembubaran ormas di tahun 2020, tidak menutup kemungkinan muncul sebagai kelompok-kelompok kecil yang lebih soft atau lebih bisa diterima masyarakat baik yang belum terpapar sebelumnya sama sekali. Peneliti menggunakan konsep conflict prediction models untuk menganalisis pola dari radikalisme pada masyarakat dari tiga kabupaten di provinsi Sulawesi Barat (Mamuju, Majene, Polewali Mandar) untuk menguji ancaman yang muncul dan mempengaruhi kebijakan. Selain itu, peneliti juga menggunakan konsep kebijakan publik untuk membuat peraturan dan kebijakan bagi pemangku kebijakan untuk menghindari ancaman yang akan datang demi kepentingan publik.
Frequencies of lateral morphs in different age classes of the flounder Platichthys flesus (Pleuronectidae) from the White Sea
Authors: Yershov P.N. , Fuks G.V. , Khaitov V.M.
Published: December 2022

In the populations of the European flounder Platichthys flesus (Linnaeus, 1758), the proportions of left- and right-sided individuals vary widely, and possible causes of this variation remain little explored. The hypothesis of ecological segregation of phenotypical morphs in the European flounder relies primarily on observations of certain differences in morphology and foraging performance between the left- and right-sided individuals. The flounders of different sex and size/age, however, can differ in the character of biotic associations with the environment and other hydrobionts. We have examined the interaction of size/age and sex of the fish with the probability of encountering left-sided individuals in 4 populations of the European flounder from the White Sea basin. The results of the study have shown that the proportion of the reversed individuals did not differ among the flounders of various size and age in all the populations studied. The proportion of the left- and right-sided morphs in different size-age classes in all investigated populations did not depend on the sex of the fish. Revealed interpopulation diversity of phenotypic composition of flounder from the White Sea is not connected with the size/age and sex structure of compared samples.
Muscle system of the penial complex in three species of Hygrophila (Gastropoda: Pulmonata)
Authors: Soldatenko E.V. , Petrov A.A.
Published: December 2022

The Hygrophila, a group comprising freshwater lung-bearing gastropods, have a complex copulatory apparatus, whose musculature has recently been shown to provide a number of phylogenetically informative characters that appear to concur with the results of molecular phylogenetic analyses. The number of hygrophilan species for which the male copulatory musculature is known, however, is still relatively small. We examined the muscle arrangement in the penial complex (penis and penis sheath) of three species of Hygrophila: Aplexa hypnorum (Linnaeus, 1758) (fam. Physidae), Kolhymorbis bogatovi Zatravkin et Moskvicheva, 1985 (fam. Planorbidae, tribe Segmentinini), and Planorbarius corneus (Linnaeus, 1758) (fam. Planorbidae, tribe Helisomatini) to explore whether the organization of the male copulatory musculature in these species is consistent with the previously proposed phylogenetic hypotheses. In A. hypnorum, the primarily glandular penis sheath has a three-layered musculature with outer and inner circular and intermediate longitudinal layers. The tubular penis also has a three-layered musculature, with the same sequence of muscle fibers as in the penis sheath. In K. bogatovi, the sequence of muscle layers in the penis sheath is essentially the same as in A. hypnorum. Penial musculature is also arranged in three layers, but the intermediate layer consists of small radial, rather than longitudinal fibers and the inner and outer layers are circular. In P. corneus, the boundaries between muscle layers in both penis and penis sheath are somewhat indistinct, but the circular muscles tend to lie close to their outer and inner walls, while the longitudinal fibers are concentrated in the interior. The comparison with other hygrophilan species, in which the copulatory musculature has been previously studied, shows that the male copulatory musculature of K. bogatovi is consistent in arrangement with that of other representatives of Segmentinini and that the phylogenetic lineage leading to P. corneus has probably diverged before the clade Planorbini + Segmentinini. The musculature of the penial complex of A. hypnorum is generally similar to that of another physid, Physella acuta (Draparnaud, 1805), but the penis sheath of P. acuta lacks an outer layer of circular muscle fibers, which may be explained by reduction.
New species Eutobrilus Gagarini sp. n. and a review of species of the genus Eutobrilus from graciliformis-group (Nematoda: Tobrilida, Tobrilidae, Eutobrilinae)
Authors: Tsalolikhin S.Ya.
Published: December 2022

A new species of Eutobrilus gagarini sp. n. from the Leningrad region is described, which is included in the morphological graciliformis-group of the genus Eutobrilus and differs from other species of the group by a high coefficient "b" and a smaller ratio of the length of the spicules to the length of the supplementary row and the ratio of the length of the spicules to the length of the body. A key for determining the Holarctic species of the graciliformis-group is given and the composition and structure of this group as a whole are discussed. The expediency of isolating the morphological graciliformis-group is discussed. The synonymization of the genus Peritobrilus Gagarin, 1993 with the genus Eutobrilus Tsalolikhin, 1981 is confirmed.
Державне регулювання операцій з імпорту в умовах воєнного стану
Authors: ФОМІНА Олена , РОМАШКО Ольга , ШАПОВАЛОВА Алла
Published: December 2022

Вступ. Значна частка в зовнішньоторго­вельному обороті України належить імпорту товарів, на який негативно вплинула війна в Україні. Верховна Рада України постійно вносить зміни у законодавство, що вимагає від суб’єктів господа­рювання оперативно приймати ефективні управ­лінські рішення.  

Проблема. Об’єктом дослідження є операції з імпорту товарів, обсяг яких з введенням воєнного стану в Україні скоротився.  

Мета статті – аналіз змін законодавства щодо імпорту товарів в умовах воєнного стану, валютних обмежень за операціями імпорту та їхнього впливу на збільшення попиту на імпортні товари з боку суб’єктів господарювання.  

Методи. Методика дослідження передбачає аналіз даних щодо вартісного обсягу імпорту за місяці воєнної агресії рф, а також тимчасових змін в законодавстві.

Результати. Розглянуто загальну структуру імпорту України за перші шість місяців агресії рф. Проаналізовано дані Національного інституту стратегічних досліджень щодо імпорту порівняно з аналогічним періодом 2021 р. Фактором змен­шення обсягів імпорту є введення воєнного стану в Україні та заборона будь-якого імпорту з рф. Для прийняття ефективних рішень щодо здійснення зовнішньоекономічної діяльності постійно вносилися зміни в нормативно-правові акти. Зміни в законо­давстві дали можливість полегшити процедури декларування окремих товарів під час перетину митного кордону, спростити документальне оформлення товарів і звільнити від оподатку­вання товари для здійснення заходів із забезпе­чення національної безпеки та оборони.  

Висновки. Війна в Україні негативно вплинула на розвиток економіки та міжнародну торгівлю. Відбулася зміна фокуса імпорту товарів, оскільки передусім завозилися товари критичного імпорту. Верховна Рада України постійно вносила зміни в нормативно-правові акти, що дало змогу суб’єктам господарювання імпортувати товар і розрахо­вуватися з нерезидентами.
Prevalencia de síndrome metabólico en adolescentes escolarizados del Departamento Central en el año 2021
Authors: Gaona Nelly , Sanabria Marta Cristina , Piris Angela , Dong Chin Suh , Pereira Patricia , Cuevas Maria Teresa
Published: December 2022

Introducción: El Síndrome Metabólico (SM) es una entidad clínica que se manifiesta por obesidad central, dislipidemia, hiperglicemia y/o hipertensión arterial y se relaciona con el desarrollo de Diabetes Mellitus tipo 2 y enfermedades cardiovasculares.

Objetivo: Determinar la prevalencia del SM en adolescentes escolarizados del Departamento Central en el 2021 y evaluar los factores de riesgo relacionados.

Materiales y Métodos: Estudio descriptivo con componente analítico. Ingresaron 279 adolescentes de 10 a 16 años de 6 escuelas elegidas aleatoriamente. Se realizó una encuesta sobre estilos de vida, prácticas alimentarias, antecedentes familiares y perinatales. Se realizó medición de peso, talla, circunferencia de cintura (CC), glicemia, perfil lipídico y presión arterial. Para el diagnóstico de SM se utilizó los criterios de Cook. Aprobado por el Comité de Ética del IICS y del Hospital de Clínicas. Para el análisis se utilizaron tablas de frecuencias, mediana y Prueba del Chi cuadrado para razón de prevalencias (RP) con nivel de significancia p < 0,05.

Resultados: Mediana de edad 13 años en general y 11,5 años en SM, 53 % fueron hombres. La prevalencia de sobrepeso fue del 22,9 % y de obesidad 26,16 %. La hiperglicemia fue del 0,01 %, hipertrigliceridemia 16 %, HDL bajo 37,9 %, Prehipertensión arterial 11% y CC > p90 36%. La prevalencia de SM fue del 10,7 %. La CC >p90 con RP de 31,4 (7,6-128), y la hipertrigliceridemia con RP de 46,8(14,8-147,7), fueron los componentes preponderantes de SM. El peso elevado al nacer y no realizar actividad física, fueron identificados como factores de riesgo significativo.

Conclusiones:  La prevalencia de SM fue 10,7%, se relacionó con mayor peso al nacimiento, obesidad y sedentarismo.
Deficiencias de cobre, hierro y zinc en niños menores de 5 años
Authors: Sanabria Gabriela , Estigarribia Gladys , Kennedy Cristel , Aguilar Gloria , Galeano Fernando , Sanabria Marta , Kawabata Aníbal , Vuyk Iris , Muñoz Sergio , Pizarro Fernando
Published: December 2022

Introducción: La determinación de niveles séricos de micronutrientes de los niños menores de 5 años, es un requerimiento básico para establecer la prevalencia de deficiencias nutricionales de la población infantil y es una estrategia útil para incentivar a Salud Pública para que tome medidas en cuanto a aplicación y/o modificación de las Políticas Alimentarias Nacionales.

Objetivo: Determinar los niveles séricos de cobre, hierro y zinc en niños paraguayos menores de 5 años.

Materiales y Métodos: Estudio observacional, descriptivo y de corte transversal. Se procesaron las muestras de sangre de 1.441 niños menores de 5 años de edad que provenían de los Departamentos de Alto Paraná, Caaguazú, Central y de la capital de Paraguay. Se realizaron hemogramas y se determinaron las concentraciones séricas de albúmina, cobre, ferritina y zinc, de todas las muestras.

Resultados: Los niños tuvieron una edad promedio de 3 años y 3 meses, fueron 52,74% de sexo masculino y 47,26% de sexo femenino. La prevalencia de anemia fue de 45,25% y la prevalencia de hipoalbuminemia fue de 20,65%. Se detectaron deficiencias de cobre en 14,03%, de ferritina en 6,98% y de zinc en 43,62%, de los niños.

Conclusión: Los resultados de este estudio avalan la necesidad de ampliar la cobertura del Programa Alimentario Nutricional Integral (PANI), de plantearse si se deben ajustar las cantidades de minerales y vitaminas de la fórmula nutricional del Programa y de mejorar el seguimiento de los controles prenatales de las madres.
ACUTE OSTEOMYELITIS OF THE MANDIBLE IN A GERIATRIC FEMALE INDIVIDUAL DURING PANDEMIC IN INDIA: A CASE REPORT AND LITERATURE REVIEW
Authors: Shunmugavelu Karthik
Published: December 2022

A 75-year-old female patient reported to our hospital with pain and swelling on the left side of the face. Patient experienced severe throbbing pain a few days after extraction. Swelling developed 2 weeks after the extraction and progressively increased in size. Past dental history revealed that she had undergone extraction of lower left second molar 1 month back. Past medical history revealed that she was diabetic and hypertensive and was under medication for the same for the past 21 years. Patient had no history of jaw fracture and radiation exposure. Radiograph features showed cortical destruction and an increase in CRP level was observed through lab investigations. Radiograph revealed radiolucency with cortical bone destruction in relation to the lower left mandibular region. Laboratory investigations revealed an elevated CRP level and an increased albumin level in urine. Based on the history, clinical features, radiographic features and laboratory diagnosis a diagnosis of acute osteomyelitis was given. Incision and drainage were done followed by antibiotic therapy. The exposed bone was removed followed by curettage and irrigation. Patient was recalled after 10 days and exhibited no post-operative complications. This case was treated with antibiotic therapy and localized surgical management. The primary goal is treatment and or elimination of the causative factor followed by antibiotic therapy instituted according to antibiogram. Surgical therapy includes incision and drainage, jaw resection in invasive and extensive cases. Decortication, sequestrectomy and saucerization can also be done. Hyperbaric oxygen therapy can be given in patients with chronic osteomyelitis associated with necrotizing soft tissue. Improved patient survival, better outcome and a decreased need for surgical intervention have been observed in patients treated with hyperbaric oxygen. Osteomyelitis is a rare, invasive and destructive bacterial infection that can affect the quality of life. Further research in diagnosis criteria and techniques for management of osteomyelitis must be developed for better outcome and patient survival.
POSSIBILITIES TO INFLUENCE UPON ORAL FLUID BIOCHEMICAL INDICES IN CHILDREN WITH CHRONIC CATARRHAL GINGIVITIS AND UNDERLYING INSULIN DEPENDENT DIABETES MELLITUS
Authors: Kaskova L. F. , Honcharenko V.А.
Published: December 2022

Оbjective of the study was to examine the effect of the suggested therapeutic-preventive complex including oral administration of the complex drug “Kvertulin”, the drops “Imupret, the polyvitaminic complex “Pikovit”, and topical irrigation of the oral cavity with the tooth wash “Exodent” on the biochemical indices of the oral fluid in children with chronic catarrhal gingivitis and diabetes mellitus. Therapeutic and prophylactic measures were performed in children with chronic catarrhal gingivitis, who were prescribed a common complex (groups 1, 2) and proposed by us (group 3), which includes drugs that have antioxidant effects. Determined: protein content by the Lowry method; assessment of POM; the content of HS-groups; activity of glucose-6-phosphate dehydrogenase (PDG); ceruloplasmin. Тhe therapeutic-preventive measures initiated have produced a positive effect on the oral cavity homeostasis and enabled to improve the indices of the study and maintain them on an appropriate level during 6 months. The most significant decrease in the total protein of the oral fluid was observed in the group of patients who were prescribed the complex proposed by us. he OMB study shows that the best results after the end of treatment were obtained in children who were prescribed a complex containing components with antioxidants. Examination of the index of HS-group activity in the oral fluid found its increase after the complex with antioxidants used. It 1.8 times increased in comparison with that one before the treatment. The most substantial changes in the activity of ceruloplasmin was found in 3 group of the study during the whole period of observation. Considerable results after the treatment initiated were found in children from 3 group who were treated according to the therapeutic-preventive complex suggested. G-6-PDG activity decreased in the course of time in all the groups of observation and till the end of the 6th month it was the highest in the 3rd group.
Efficacy of the ABCDE Bundle to Improve the Outcome of Patients in the Intensive Care Unit
Authors: Patkar Ankita Adesh , R. Mohite Vaishali , K. Choudhari Samir , Shinde Mahadeo
Published: December 2022

Introduction: A multidisciplinary team, cutting-edge technology, and state-of-the-art equipment are all available to severely sick patients in intensive care units. These facilities also provide continuous monitoring of patients who are in critical condition. Aims: To improve a patient’s physical and cognitive status. Materials and Method: An observational study that was not experimental was conducted out on patients receiving mechanical ventilation in the intensive care unit. The non-probability convenient sampling method was used to recruit a total of three hundred and fifty samples for the sample. The intensive care unit was the setting for the investigation. Patients who were hospitalised to the ICU and were receiving support from a mechanical ventilator were considered for participation in this study. Result: The findings indicate that out of 350 patients, 48.9% fell within the age range of 51–70 years, while 96 patients (27.4%) were older than 70 years. Regarding the question of gender, 56.6% of them were men while 152 of them (43.4% of the total) were females. According to the findings of this study, 1.4% of patients exhibited inadequate performance on the sedation awakening trial (SAT). The SAT scores of 32.9% of patients were considered to be average, while 65.7% of patients had good SAT scores. 2.3% of patients had a low score on the Spontaneous Breathing Trial (SBT), 46.6% of patients had an average score for the SBT, and 51.1% of patients had a high score on the SBT. Conclusion: The process of deploying the ABCDE bundles is producing improved results for the outcomes of patients who are being treated in the intensive care unit.
Efficacy of an Information Booklet on Menstrual Knowledge and Attitude Among Adolescent Boys and Girls in a Rural Cbse School
Authors: Shinde Mahadeo , Katti Anagha
Published: December 2022

Introduction: The onset of menstruation coincides with the beginning of the puberty stage in females, as menstruation is a physiological process. According to the World Health Organization (WHO), the teenage phase occurs between the ages of 10 and 19. The use of sanitary pads, their appropriate disposal, and subsequently the appropriate washing of the vaginal area, followed by hand washing, are all components of good menstrual hygiene practices. Aims: The purpose of this study is to evaluate how well an information booklet can improve adolescents’ preexisting knowledge of and attitude toward menstruation in both male and female students. Methods: A descriptive research strategy was utilised for this study as the methodology for the investigation. The research was carried out at the KCT SCHOOL in Karad. Through the utilization of the Convenient Sampling Method The study included a sample size of one hundred. A questionnaire with a defined format served as the primary research instrument. Both descriptive and inferential statistics were used in the process of data analysis. Result: The findings of the current research indicate that out of a total of 100 adolescents (50 boys and 50 girls), 29 of them had average knowledge and 68 of them had inadequate knowledge before the exam. Following the presentation of the module on menstruation, the vast majority of them achieved a score of 92 or higher on the post-test. The knowledge level of the adolescent males and girls was significantly different before and after the exam, and this difference was statistically significant. The current research demonstrates that there is a statistically significant association between the source of information and the amount of knowledge demonstrated on the pre-testing phase. Conclusion: The findings of the study indicate that participants’ understanding of menstruation is inadequate, as the conclusion of the study states. They need a comprehensive orientation procedure that will help them expand their knowledge while also assisting them in making informed decisions.
Assessment of Security Officers’ Perceived Stress in a Tertiary Care Setting
Authors: Patil Sngeeta , Kamble Dhanjay , Shinde Mahadeo
Published: December 2022

Introduction: The job of a security guard is extremely difficult because it requires working overnight shifts in a hostile atmosphere. The aggressive and violent relatives of the thieves are another factor that the security officers working in the hospital need to take into consideration. They go through stressful situations due to the nature of their employment and the amount of strain they are under. In today’s world, day-to-day existence is fraught with demands, problems, and tight deadlines. Many people experience stress on such a regular basis that it has become a routine part of their lives. There are times when stress is beneficial. In low dosages, it has the potential to improve a person’s performance and drive them to achieve their full potential. Aims: The purpose of this study is to determine how stressed out the security guards at the Tertiary Care Hospital in Karad feel they are. Methods: The current study involved 79 participants, and it made use of a method called convenient sampling to choose them. For the purpose of determining stress levels, a questionnaire based on the perceived stress scale (PSS 10) was utilized. The current study uses an adequate random sampling strategy to collect 79 samples from the security guards working in Karad’s tertiary care hospital. For the purpose of this study, Cohen’s Perceived Stress Scale (PSS 10) was utilized. Result: Majority There was a perceived level of moderate stress among 64.56% of security guards, while there was a perceived level of light stress among 20.25% of security guards. Only 15.19% of security guards reported having extreme stress levels in their jobs. There was a statistically significant connection between socioeconomic factors such family income, food pattern, and smoking behavior. There is no statistically significant connection between any of the other socio-demographic factors, such as age, gender, the kind of family, the amount of alcohol consumed, and so on. The findings of this study indicate that security guards are exposed to a significant amount of stress on the job. In order for children to be able to deal with this stress, they need to develop suitable coping techniques. Conclusion: Specific measures to alleviate the stress of security guards linked with commonly recurring causes, as well as measures to increase performance associated with compensation and independence, are effective in improving the overall quality of the employees in their work environment.
A Comparative Analysis of the Study Patterns of Day Scholar Versus Hostler Nursing Students
Authors: Phuke Manda Jaywant , Mohite Vaishali , Shinde Mahadeo , Karale Rajashree , Katti Anagha , Mulani Afsana
Published: December 2022

Introduction: ”Education is the greatest treasure” Education leads to success. Students must acquire effective study habits to improve their academic success. Step-by-step, study habits can be modified. This is why researchers want to compare hostler and day scholar study patterns. Aims: (1) To assess study habits of hostler and day scholar students, (2) To compare the study habits, time Budgeting, Concentration, Memory, Note Taking ability, factors in learning Motivation, Achievement in the examinations, Test Preparation And Test Taking, Test Anxiety Management as a dimension of study habit between hostler and day scholar students. Methods: A descriptive survey of 418 undergraduate and postgraduate students, including 205 hostler and 213-day scholars. Result: Delmar .edu/student life/tutoring uses the SHI. Out of 418 respondents, more B.Sc. nursing students responded than P.B. and M.Sc. nursing students. 64.6% of respondents have fair study habits, 28.95% have good, 5.98% have poor, and 0.48% have exceptional. Conclusion: Hostler and day scholar students had different study habits in every other areas except test preparation, test taking, and note taking. Study habit is a student’s predisposition to study, whether it’s systematic or unsystematic, efficient or inefficient, and suggests a persistent method of learning. Various students have different study habits, but student success depends on appropriate study habits. To improve study habits, be conscious of your own.
Nurses’ Levels of Assertiveness and Self-Esteem in a Healthcare Facilities
Authors: K. Choudhari Samir , Shinde Mahadeo
Published: December 2022

Introduction: It is generally accepted that assertiveness and high levels of self-esteem are healthy behavioural qualities for all people to possess. It is well acknowledged that assertiveness is one of the most crucial behavioural characteristics for professional nurses. Aims: The purpose of this study was to determine the levels of assertiveness and self-esteem that are held by nurses that work in a certain hospital Materials and Methods: This research was conducted in a non-experimental setting among Registered Nurses, and a total of sixty of them were chosen through the use of the Simple Random approach. The research was started once approval had been granted by the environment and informed consent had been obtained from the participants. The use of a structured questionnaire allowed for an evaluation of nurses’ assertive behaviour as well as their levels of self-esteem. Statistics, both descriptive and inferential, were applied to the study of and analysis of the data that had been obtained. Result: The findings of this study reveal that the majority of nurses working in hospital settings have a self-esteem that is higher than average, with 60% of them having higher self-esteem than the other 40%, who had an average level of self-esteem. While 63.33 percent of nurses displayed good assertive behaviour and 36.67 percent displayed average assertive behaviour, Conclusion: The study came to the conclusion that the majority of the nurses had a high or medium degree of self-esteem while they were working in their separate settings, and that their behaviour was also found to be forceful.
LIQUID BIOPSY IN CLINICAL ONCOLOGY
Authors: Imyanitov E.N. , Kuligina E.Sh. , Janus G.A.
Published: December 2022

Liquid biopsy is the analysis of tumor fragments (entire cells, nucleic acids,proteins) in hysiological and pathological body liquids. This technology has already been included in standard procedures of detecting secondary mutations, which are associate with acquired drug resistance. Liquid biopsy is a promising tool for early cancer detection, evaluation of the success of radical cancer surgery, monitoring of residual tumor disease, assessment of treatment efficacy etc.
PENGELOLAAN SURAT MASUK DAN SURAT KELUAR BERBASIS WEB PADA JURUSAN ADMINISTRASI NIAGA POLITEKNIK NEGERI UJUNG PANDANG (STUDI KASUS PRAKTEK PENGELOLAAN SURAT PADA MATAKULIAH SIMULASI BISNIS)
Authors: Aisyah Ramadhani Tasya Nurul , Aryani Eva , Amiruddin Amiruddin , Imasita Imasita
Published: December 2022

One of the practical activities in the business simulation course is the mail management process, which includes: delivery, storage, and archive discovery. Currently, the management of letters in this practice is still manual which results in the use of a lot of time, energy, and costs and frequent errors, scattered or damaged documents. This study aims to produce a website-based letter management application that can facilitate mail management, especially in the practice of managing letters in business simulation courses. The research method used is design research using the waterfall method. The stages or procedures carried out consist of 1) Needs Analysis, 2) Data Collection, 3) System Design, 4) Testing, 6) Implementation. Furthermore, the data collection techniques used are: 1) Interview, 2) Observation. The results of the study indicate that the resulting application can facilitate the management of letters, especially in the use of time, effort and cost.
OPTIMALISASI KUALITAS PELAYANAN MAHASISWA MELALUI PENGELOLAAN ARSIP DINAMIS DI PERPUSTAKAAN POLITEKNIK NEGERI MANADO
Authors: Mandulangi Jufrina , P.T. Makinggung Juliet , Kasenda Sonny , Luntungan Frans
Published: December 2022

Libraries are institutions that carry out service-based activities. The fact is that to borrow books in the library needs long time affecting completion of students’ final project. There are also library officers serving students angrily. Consequently, many students look for books elsewhere. It is assumed that the optimization of student service quality is influenced by dynamic archive management at the Manado State Polytechnic Library. This study uses quantitative analysis in the form of multiple regression and correlation levels by carrying out several tests, namely classical tests such as multicollinearity, heteroscedasticity, and autocorrelation tests using the SPSS version 26 computer program. The results of the research showed that archive management storage systems, archive management officers, archive managemet knowledge have a positive and significant impact on students’ satisfaction. Meanwhile, archive managemet equipment had no effect on students’ satisfaction.