bluuebunny/crossref_metadata_2025 huggingface dataset:
KONSEP DAN APLIKASI PENDIDIKAN SAINS DI SEKOLAH DASAR
Authors: Topik Topik
Published: December 2024

Sains merupakan suatu ilmu yang bersifat body of knowledge, yang mana suatu cabang ilmu pengetahuan yang bersifat pembuktian observasi dan klasifikasi fakta-fakta yang disusun berdasarkan hukum umum dengan induksi dan hipotesis. Sains merupakan suatu rumpun ilmu yang memiliki karakteristik untuk mempelajari fenomena alam yang secara faktual (faktual), baik yang berupa kenyataan (reality) atau kejadian (events) berhubungan sebab akibat. Dalam konsep pendidikan sains, seorang anak didik sangat dituntut untuk berfikir semaksimalmungkin sehingga dapat menyelesaikan permasalahan-permasalahan yang ada di lapangan dengan pendekatan yang bersifat dihasilkan dari inkuiri. Di samping itu, pendidikan sains merupakan pengetahuan yang sistematis dan tersusun secara teratur, berlaku umum, danmerupakan suatu kumpulan data dari hasil observasi dan eksperimen memiliki empat penting yang mencakup; sikap, proses, produk, dan aplikasi. Dalam hal ini anak SD/MI akan lebih diarahkan untuk diberi kesempatan dan mencari tahu apa yang diperoleh di sekolah sertadiimplementasikan berdasarkan bukti-bukti ilmiah, guru salah satu yang sangat berperan dalam pendidikan sains harus menjadi sebagai fasilitator untuk mengarahkan anak didik sebagai salah satu pusat pembelajaran.
The Impact of Parasocial Interaction and Local Presence on Impulsive Buying Behavior on TikTok
Authors: Feby Laurencia , Riza Fahrul , Kristanti Dwi Anna
Published: December 2024

TikTok, as a social media platform, has significant potential to influence consumer purchasing decisions through content creators and live streaming features. Live streaming facilitates parasocial interactions with hosts and co-viewers, as well as local presence, which can impact consumers' perceived product values and impulsive buying behavior. This study examines the effects of parasocial interactions, both with hosts and co-viewers, and local presence on utilitarian and hedonic values, ultimately leading to impulsive buying behavior. Using a quantitative approach, data were collected through questionnaires distributed to respondents selected through purposive sampling. Analysis was conducted using Structural Equation Modeling (SEM) with the assistance of SmartPLS. The results revealed that parasocial interactions and local presence significantly influence consumers’ perceived values, which in turn affect their impulsive behavior. These findings contribute to the literature by highlighting the mediating role of these values in the relationship between social elements and impulsive behavior. Further research is encouraged to explore these dynamics in greater depth, as well as to examine differences across various platforms and cultural contexts.
Appraisal of Some Modern Assessment Techniques in Science Education
Authors: Konyeme Josephine Ese , Oliweh Ifeanyi Solomon
Published: December 2024

Researches into effective science teaching at primary school provide us with two important information; the ideas that science teaching and learning of children should start at school and understanding of a concept is the fundamental of the learning. Recently, the quality of teaching and learning science becomes the question in hand. A lot of researchers agree that objectives of learning science at primary and secondary schools may not be only to prepare students for the secondary stage education, it is also important for the preparation of lifelong learning and understanding of the phenomenon around them. Today, there is a fundamental shift from testing to learning as assessment is perceived as integral part of teaching-learning process. This shift has also brought a shift in traditional ways (tools and techniques) of assessment. Tasks like role plays, crossword puzzle, flow charts, popular science, book review, field trips, class work/homework assignments, group work, survey, project work, worksheets, games, etc. became tools for assessment. This paper discusses role plays, debate and flow charts as tools and techniques, which can be used by teachers in science classroom.
New data on the distribution and biology of Jordanita (Roccia) volgensis (Möschler, 1862) (Lepidoptera: Zygaenidae, Procridinae) in the Crimea
Authors: Efetov Konstantin A. , Gorbunov Oleg G.
Published: December 2024

Jordanita (Roccia) volgensis (Möschler, 1862) is found in the western part of the Crimean Peninsula where its larval host-plant is Achillea leptophylla M. Bieb. (Asteraceae).
First trimester bleeding and pregnancy outcomes: A case-control study
Authors: Temur İsa , Karaman Enes
Published: December 2024

Aim: The objective of this study is to perform a comprehensive assessment of fetal and perinatal results in pregnant women diagnosed with threatened miscarriage during the early trimester, and to evaluate the potential impact of this condition on the progression of pregnancy.
Materials and Methods: In this retrospective study, the study group consisted of 200 patients who were diagnosed with threatened miscarriage and gave birth, while the control group was composed of 200 patients who gave birth without experiencing threatened miscarriage during the same period. The following variables were evaluated: age, gravida, parity, gestational week, and body mass index (BMI), as well as fetal and maternal perinatal outcomes.
Results: The analysis of the delivery parameters revealed no statistically significant difference between the groups in terms of mode of delivery (p=1.000). The prevalence of preterm birth and preterm premature rupture of membranes (PPROM) was significantly higher in the case group compared to the control group (p < 0.001). No statistically significant difference was observed between the threatened miscarriage group and the control group in terms of the incidence of gestational diabetes, preeclampsia, placenta previa, abruptio placenta, macrosomia and stillbirth (p>0.05).
Conclusions: In pregnant women with threatened miscarriage, the risk of preterm birth and preterm premature rupture of membranes (PPROM) is significantly higher. This finding emphasizes the need for careful monitoring and management of these patients, particularly concerning complications such as preterm birth and PPROM.
THE IMPACT OF THE COVID-19 PANDEMIC ON THE DIAGNOSIS AND TREATMENT OF ECTOPIC PREGNANCY: A RETROSPECTIVE COMPARISON
Authors: Özbilgeç Sıtkı , Akkuş Fatih , Sarıkaya Sevcan , Dönmez Emin Erhan , Durmaz Rahime Berfin , Acar Ali
Published: December 2024

Objective: To investigate the impact of the COVID-19 pandemic on the diagnosis and treatment processes of ectopic pregnancies (EP) at a tertiary hospital in Turkey.

Methods: This retrospective study compared 221 cases of tubal EP diagnosed after March 15, 2020, with 217 cases diagnosed before this date. Patient demographics, clinical characteristics, and treatment modalities were analyzed. Statistical analyses, including independent t-tests, Chi-square tests, and multinomial logistic regression, were conducted to assess differences between the COVID and pre-COVID periods.

Results: The study found no significant differences in maternal age, gravidity, parity, or gestational weeks between the COVID and pre-COVID periods. However, there was a notable increase in patients presenting with abdominal pain (52.5% vs. 37.8%) and intraperitoneal hemorrhage (26.7% vs. 7.4%) during the COVID period. Despite the higher frequency of abdominal pain, vaginal bleeding was less common during the pandemic. Treatment approaches also shifted, with a significant increase in medical management (41.2% vs. 29.0%) and a slight decrease in surgical interventions during the COVID period. Multinomial logistic regression revealed that parity, gestational week, presence of Douglas fluid, and the period of diagnosis (COVID vs. pre-COVID) were significant predictors of treatment modality.

Conclusion: The COVID-19 pandemic influenced the clinical presentation and management of ectopic pregnancies in our hospital. While there were no significant differences in key demographic or laboratory parameters, the increased presence of abdominal fluid and a shift towards medical management during the pandemic period suggest changes in patient presentation and treatment preferences. This study underscores the importance of maintaining vigilant diagnostic and therapeutic approaches for EP, even during global health crises.
De la désaffiliation dans My Son the Fanatic (Udayan Prasad, 1997)
Authors: MARIN-LAMELLET Anne-Lise
Published: December 2024

Avec le recul, My Son the Fanatic s’est avéré un film prophétique, à rebours de nombreuses comédies d’intégration se voulant optimistes et célébrant les joies du multiculturalisme. En racontant l’histoire d’une désintégration à la fois familiale et sociale, cette tragicomédie grinçante annonçait dès 1997 les dangers du repli identitaire et du communautarisme. À travers le conflit larvé d’un père pakistanais et de son fils britannique, ce film pose des questions fondamentales autour de la nature de l’identité, de la complexité des allégeances dans un contexte postcolonial, et de la transmission d’un héritage dans le processus de création de la citoyenneté. Au-delà d’une simple opposition binaire, il multiplie les personnages secondaires pour nuancer leur rapport négocié à la britannicité et plonge au cœur de la noirceur pour in fine promouvoir l’individu dans son humanité avec toutes ses failles.
Lisser l’avenir : le « journal » de Patrick Gass et la peinture de l’Ouest
Authors: ATEM Florent
Published: December 2024

Lorsqu’il entame en mai 1804 la remontée du Missouri en tant que membre de l’expédition Lewis et Clark, Patrick Gass ignore qu’il s’apprête à jouer un rôle fondamental au sein du Corps de la découverte. Outre les innombrables services rendus dans le cadre du périple jusqu’à la côte Pacifique, le charpentier de la troupe est également l’un des sept diaristes du groupe. Publié dès 1807, un an après le retour triomphal à Saint-Louis, son récit de l’aventure constituera, sept années durant, l’unique témoignage de l’épopée américaine jusqu’aux confins de la wilderness ; véritable invitation au voyage, il attisera à lui seul la flamme du désir expansionniste. En ce sens, au-delà du caractère en apparence linéaire et chronologique de sa narration, bien plus qu’une expérience passée léguée à la postérité, c’est bel et bien une vision de l’avenir de la nation que Gass, au fil des pages de son « journal », donne à voir à ses concitoyens.
Shifting Geological and Literary Lines in H. G. Wells’s The Island of Doctor Moreau and Joseph Conrad’s Lord Jim: A Geoliterary Approach
Authors: GAY Julie
Published: December 2024

This article adopts a geoliterary approach to explore the way some travel and adventure writers were shifting literary lines at the turn of the 19th century, especially through their use of vertical fault lines. In H. G. Wells’s The Island of Doctor Moreau or Joseph Conrad’s Lord Jim, as the characters explore unknown islands or enclaved spaces, they are confronted with literal “chasms” which they have to cross or explore in order to progress in their journeys. Such geological interruptions often represent hurdles in the travellers’ trajectories, and subsequently give them access to a new, previously unknown world or reality. Crossing these rifts may then result in a shift in genre, or at least in narrative rhythm and style. As the hero is put to the test, these spatial chasms sometimes reveal and even mirror the fault lines in his very identity, but also in the homogeneity and consistency of the narratives. The faulty travellers’ narratives are indeed often fraught with gaps and contradictions, which some critics have interpreted as symptomatic of the work’s flawed nature. However, this paper argues that such hiatuses in fact evince these works’ disruptive hybridity, and their utter modernity.
Shifting lines in Jan Kerouac’s Baby Driver. A Story about Myself (1981)
Authors: MORGAN-PROUX Catherine
Published: December 2024

In her autobiographical novel Baby Driver. A Story About Myself (1981), Jan Kerouac, the little-known daughter of renowned writer Jack Kerouac, recounts a tumultuous life journey drawn largely from her own personal experience. This article explores the shifting lines between Jan Kerouac and Jack Kerouac, revealing profound fractures in the vertical line, or lineage, between father and daughter. Moreover, Jan Kerouac’s nomadic life is linked to another disrupted family line, that between her and her stillborn daughter. This fractured line of vulnerability and disenfranchised grief underlies the narrative, shaping the way Jan Kerouac navigates through the world. The text captures her chaotic life on the road as well as her search for catharsis through writing. Despite Jan Kerouac’s unique perspective, her work has been largely overlooked, especially in the context of women’s road narratives. This study puts forward the case that Jan Kerouac's work is deserving of more visibility in the landscape of travel literature.
A Guiding Line? Rethinking the Road in American Post-Apocalyptic Narratives
Authors: HUU Cécile DO
Published: December 2024

In the USA, road lines guide both American travel literature and the nation’s history of westward expansion. From western films to road movies, the road has become a specific space-time woven from the mythologies of the Frontier, wilderness, progress, as well as an imaginary of freedom and new beginnings. However, traditional road representations now face technological advances, environmental consciousness, and global crisis. The rise of post-apocalyptic road narratives signals a genre shift, questioning the myth of universal mobility tied to an ideologic conception of liberty. This study delves into this evolution, analyzing pessimistic yet realistic post-apocalyptic road novels and films like Cormac McCarthy’s The Road, John Hillcoat’s adaptation, Dave Eggers’s Heroes of the Frontier, and Casey Affleck’s Light of my Life. Drawing from Bakhtin’s chronotope theory and the transmedial nature of the road narrative, it investigates how the road operates as a space-time for individual travel tales and the American national narrative, undergoing shifts in mobility, history, and narration. The post-apocalyptic backdrop redefines family ethics within the road narrative, envisioning the road as a space-time for transmitting stories and collective memories.
Performing Grief Inconsolable: Land, Lament and Love in Marina Carr’s Portia Coughlan
Authors: ANGELAKI Vicky
Published: December 2024

The article concentrates on Marina Carr’s seminal play Portia Coughlan (1996), examined through an ecocritical and ecofeminist lens. As the essay argues, the play’s recent revival at London’s Almeida Theatre (2023), directed by Carrie Cracknell, designed by Alex Eales and featuring Alison Oliver in the lead role, made a considerable contribution towards highlighting the roots of discomfort as well as the embodied experience of Carr’s eponymous heroine, towards emphasising concerns of grief and inconsolability, but also towards asking how consolation and agency may be conceivable for spectators within an environmentally focused staging and reading of the play. As the article proposes through an interdisciplinary reading engaging with dialogues focused on environmental discourses, the pastoral, and theatre studies (especially related to Carr), the resonance of Portia Coughlan not only endures as it approaches its thirty-year anniversary, but is also recharged vis-à-vis ecologically orientated imperatives in current theatre scholarship and the broader socio-political realm.
"A watering of her desert": Depression and (Dis)consolation in Jenny Diski’s Monkey’s Uncle
Authors: GAGNERET Diane
Published: December 2024

Jenny Diski’s work has consistently offered a direct and daring exploration of many facets of human experience, including the most traumatic. Her 1994 novel Monkey’s Uncle, charting a middle-aged woman’s descent into depression following two cataclysmic events, qualifies as a work that seems all about inconsolability, yet invites a reflection on what David James calls “discrepant solace.” This paper will dwell on how contentious the notion of consolation reveals itself to be in a narrative which, steeped in experiences of loss and mourning, seems to foster disconsolation understood alternately as dismissal of, diversion from and reversal of expected consolatory practices and effects. To Diski’s protagonist, the loss of political ideals is more personal than the demise of her own child; the relentless despair experienced in depression becomes “a comforting trench into which she could curl safely” and no amount of therapy can match the obsessive reading of the book in which she immerses herself, and the readers. The novel may thus offer an exemplary case study in the art of (dis)consolation, suggesting that the comforting powers of uncomfortable stories should not be excluded from critical consideration.
Drifting as Consolation in Michael Ondaatje’s Anil’s Ghost
Authors: MISRAHI-BARAK Judith
Published: December 2024

Michael Ondaatje’s Anil’s Ghost deals with the exhumation and identification of bones in the context of the civil war in Sri Lanka. Sent by a human rights group to investigate mass burials, Sri Lankan-born and North American-educated Anil Tissera returns to her native island as a forensic anthropologist after 15 years away. Invested as she is in her job, Anil needs time to authorize herself to be affected by what she uncovers. The reconstruction of her relationship with the excruciating history of the island takes unusual narrative shapes in the novel, which has been criticized for meandering along too many digressions and for “drifting […] away from the book’s essential business” (Maslin 11). As I investigate what can be referred to as literary drifting, I offer the hypothesis that such drifting is the route the novel takes to steer the protagonist and the readers from desolation to consolation. I argue that, far from diverting us from the main forensic purpose of the book, Ondaatje’s literary drifting contributes to creating a new space and time for the desolate and the inconsolable, as if solace could only be found in the relational engagement with a community.
Consoling the inconsolable? Writing, telling and persistent pain in Robert Arthur Alexie’s Porcupines and China Dolls
Authors: MIROUX Franck
Published: December 2024

This paper examines Gwich’in writer Robert Arthur Alexie’s 2002 novel Porcupines and China Dolls through the prisms of consolation and healing. It shows that Alexie challenges the widespread idea of reconciliation as a path towards closure. Drawing on both Indigenous and non-Indigenous critical theory, it contends that consolatory discourses as they appear in the novel do not guarantee full recovery but may even bring more pain by exposing too deep a wound to be mended. While this article stresses that the notion of inconsolability is a core issue in a narrative essentially concerned with the acceptance of loss, it also demonstrates that some degree of solace can be achieved through the restoration of a sense of tribal identity.
L’Algérit : le rire d’Assia Djebar
Authors: Weltman-Aron Brigitte
Published: December 2024

Les critiques d’Assia Djebar ont remarqué la valeur accordée au silence ou au cri dans son œuvre. Cet article examine une variante de l’expression non articulée chez Djebar, à savoir le rire. La subversion de l’éclat de rire, surtout féminin, est particulièrement favorisée lorsqu’elle est associée à la dénonciation de la verbosité et au déploiement de l’imagination. Cependant, Djebar peut préférer d’autres formes de joie, ce qui permet d’évaluer la place contrastée du rire dans l’architecture générale de l’œuvre et dans sa pensée.
Rire en groupe (littéraire) : poétiques et stratégies du rire chez les collectifs contemporains
Authors: Baud Jean-Marc
Published: December 2024

Cet article se propose d’analyser les formes et les fonctions du rire dans la poétique et la stratégie des groupes littéraires depuis les années 1990, à partir d’un corpus composé de six collectifs francophones (Perpendiculaire, BoXon, Inculte, L’armée noire, AJAR et RER Q). Force cohésive, terrain de jeu et d’expérimentation, mode de séduction ou de distinction, le rire remplit de nombreux rôles chez ces collectifs, qui poursuivent là une tradition ancienne. C’est cette piste généalogique que l’article s’attache à remonter pour étudier ce rire collectif, entre héritage carnavalesque, continuation du geste comique des groupes des XIXe et XXe siècles et adaptation aux mutations technologiques, artistiques et sociales contemporaines.
Rire aux éclats en lisant Fabrice Caro alias Fabcaro. Quand l’humour voyage de la bande dessinée au roman
Authors: Demoulin Laurent
Published: December 2024

Fabrice Caro est surtout connu, sous le pseudonyme de Fabcaro, comme dessinateur et scénariste de bandes dessinées (il est l’auteur, notamment, de Zaï zaï zaï paru en 2015 et du scénario d’un épisode d’Astérix, L’iris blanc). Mais, depuis ses débuts, il poursuit en parallèle une carrière de romancier. L’humour dans les deux pans de son œuvre correspond assurément à un enjeu spécifique tant il est omniprésent. On peut, en effet, sans trop de risque, affirmer que le rire est au cœur de sa poétique. Le présent article a pour but de cartographier les procédés et les dispositifs humoristiques à l’œuvre dans les romans de Fabrice Caro : le comique de caractère, la satire sociale, les références culturelles contrastées, les situations incongrues, l’humour noir, l’humour sexuel, scatologique ou urologique, le running gag, les calembours, les parodies, les exagérations, la mauvaise foi. Brièvement, en conclusion, ces procédés seront comparés avec ceux qui sont exploités et mis en place dans ses bandes dessinées signées Fabcaro. Fabrice Caro adapte-t-il sa palette humoristique au genre pratiqué ? Telle sera la question à laquelle nous chercherons à répondre in fine.
Le gai savoir de Mathias Énard
Authors: Fontaine Kathryne
Published: December 2024

Cet article analyse la manière dont Mathias Énard manie l’humour et l’érudition dans Le banquet annuel de la Confrérie des fossoyeurs, une œuvre où le rire se conjugue avec une réflexion profonde sur l’existence et la connaissance. En s’inspirant du concept de “gai savoir” de Nietzsche, l’étude montre comment ce roman d’Énard constitue un hommage contemporain à la sagesse joyeuse.
Ironie vs humour : Éric Chevillard, ou l’homme qui rit
Authors: Grosso Alessandro
Published: December 2024

Quelle est la différence entre l’ironie et l’humour ? Après avoir rappelé quelques propositions théoriques formulées au cours des dernières décennies qui permettent de différencier ces deux notions, l’article examine la manière dont Éric Chevillard les a conceptualisées dans ses œuvres et dans les discours d’accompagnement. On conclura que la prise en compte du phénomène du rire, qui constitue pour l’écrivain l’exutoire idéal de ces deux pratiques, permet de mieux comprendre les enjeux de son œuvre tout en échappant à une alternative problématique. Ironiste désenchanté, enclin au pessimisme, humoriste subtil à la vivacité enfantine, Chevillard aime à se présenter, au sein de ses textes, comme un homme qui rit de manière incontrôlable et qui voudrait impliquer son lecteur dans ce “ricanement” effréné. Il en résulte une curieuse posture auctoriale, qui a quelques antécédents dans l’histoire de la littérature française.
Le rire des récits de transfuges
Authors: Moricheau-Airaud Bérengère
Published: December 2024

Contribuer à l’exploration de la place accordée au rire par la littérature francophone contemporaine implique d’examiner les formes, les mécanismes et les fonctions du rire dans l’écriture des récits de transfuges, ceux d’Annie Ernaux principalement, ceux de ses épigones également, qui se multiplient ces dernières années. Le rire y assure la démarcation des groupes, car il sépare ceux qui rient de ceux qui ne rient pas, ceux dont on rit de ceux qui en rient, ceux à qui la volonté de s’élever ne laisse pas d’autre choix que de rire avec les autres. Le rire est aussi un marqueur de groupe car il en est une caractéristique notable : le rire est propre au cercle auquel on appartient, à sa classe, à son âge considéré. Le rire, par sa distanciation, par sa mise en situation, par son émancipation, est un témoin et une ressource de distinction sociale.
L’humour comme thérapie dans l’œuvre (auto)biographique d’Emmanuel Carrère
Authors: Baes Pamela
Published: December 2024

Si les thèmes de la folie, de l’enfermement, de la mort innervent la production littéraire d’Emmanuel Carrère, l’écrivain parvient malgré tout à tisser un lien entre le rire et le sérieux en adoptant une posture humoristique. Élément essentiel de l’œuvre, l’humour possède des vertus thérapeutiques. Le recours à l’autodérision, forme “raffinée” de l’humour, offre à l’écrivain l’occasion d’une prise de distance avec soi-même. A contrario, lorsque l’humour emprunte la voie de la dérision ou de l’humour noir, le rire change de couleur et se mue en “ricanement” proche du sarcasme.Cet article étudie le rôle du discours humoristique et les procédés de l’humour employés par Carrère dans ses (auto)biographies. Proche du processus sublimatoire, l’humour panse les blessures narcissiques d’un écrivain, sans cesse en quête de gloire. Grâce au principe de “subjectivation”, l’auteur offre son intimité à lire et suscite, outre le (sou)rire, la bienveillance du lecteur, au risque de voir la critique désacraliser la figure auctoriale.
L’humour à rebours
Authors: Turin Gaspard
Published: December 2024

Face à des romans surécrits, surchargés de métaphores téméraires, où se côtoient en outre le cliché, l’allitération osée, l’enflure, voire l’impropriété lexicale, où affleure à tout moment la volonté de faire artiste, dus à des auteurs à la présence médiatique forte et publiant dans des maisons d’édition prestigieuses, certains critiques (Jourde, Chevillard, Domecq entre autres) choisissent de dénoncer le scandale. Une autre attitude de lecture est possible pourtant, qui consiste à en rire, d’une allégresse franche, teintée même d’admiration. Une lecture microtextuelle est alors adoptée, permettant au rire de s’épanouir et de se partager. Mais une inquiétude apparaît alors, parce qu’une telle lecture à contre-emploi ne peut avoir lieu qu’en mobilisant une ironie particulière, où la distance d’avec le satirisé est constamment mouvante, et où une telle instabilité menace également la communauté à laquelle croit appartenir le satiriste. Rire de, rire contre ou rire avec en deviennent indissociables, et cette indissociabilité apparaît alors comme la condition même d’un tel rire.
Rire pour ne pas pleurer
Authors: Obiono Sandra Mefoude , Larose Marie
Published: December 2024

Miroirs grossissants d’une paupérisation observée par-delà les océans, les textes de Guillaume Oyono Mbia et de Gary Victor dérangent, font rire et, même, embarrassent par le caractère tragi-comique de leurs représentations. À travers des récits enracinés dans la tradition orale et la magie des réalités locales, ces auteurs dévoilent l’absurde caractérisant leurs sociétés respectives, tant dans la sphère sociopolitique que dans les rapports avec la famille et le monde extérieur. Figures généralement caricaturales, leurs personnages évoluent dans un environnement souvent chaotique ou en grande mutation, à l’image des lieux qu’il reproduit. À partir d’une analyse comparative articulée autour de Mvoutessi et Port-au-Prince, principaux lieux de l’énonciation dans certaines œuvres d’Oyono Mbia et de Victor, cet article explore les procédés esthétiques utilisés par ces derniers dans leurs usages multiformes du rire. Il examine la nature de ce rire “de village” ou de “Ville tête en bas” – acte subversif qui permet de questionner, de dénoncer et de railler l’autorité publique –, ainsi que les stratégies humoristiques mises en œuvre par les deux auteurs pour contourner la censure et masquer la parole critique. Qu’il s’agisse des pratiques narratives de la tradition orale, de l’invitation de l’assemblée ou de la lodyans, de la cocasserie ou du réalisme magique, ces parades inspirées du terroir et des réalités environnantes établissent un pacte dans le rire entre les auteurs et leur public, pris au piège d’un plaisir complice qui n’affranchit ni de la gêne ni de la honte des faits décriés. Ce faisant, l’article démontre également – par les thématiques abordées et le rire grotesque face à l’impuissance et à l’absurde –, la fraternité manifeste entre le Cameroun et Haïti.
La relazionalità della proprietà collettiva. Commons e conservazione conviviale in Umbria, Italia
Authors: Ravaioli Michele
Published: December 2024

Il presente contributo, inserito nel quadro delle geografie della montagna, propone un’analisi critica della proprietà collettiva, come esempio virtuoso di governance territoriale, mettendo a dialogo i property studies con i concetti di bene comune e conservazione conviviale. Strutturanti una serie di relazioni sociali basate su obblighi reciproci e valori condivisi tra i membri della comunità, nell’ambito di una partecipazione attiva alla gestione territoriale promossa dalla condizione di proprietà condivisa della terra, i domini collettivi rappresentano peculiari beni comuni fruiti e curati dalle collettività locali. In particolare, la messa in comune della proprietà fondiaria e della gestione territoriale promuove processi di conservazione conviviale a livello socioecologico, mentre l’implementazione di rapporti di proprietà individuale tende a favorire fenomeni di sfruttamento incontrollato delle risorse e atteggiamenti individualistici. L’analisi dei casi studio, ovvero le Comunanze Agrarie umbre di Massa Martana e Colpetrazzo, conferma la relazionalità positiva della proprietà collettiva, contrapposta alla socializzazione di spazi e persone derivante dalla territorializzazione della proprietà privata individuale, poiché permette il mantenimento di beni e spazi comuni che garantiscono una governance territoriale diretta e democratica capace di contrastare le attuali sfide socioambientali.
Phytochemicals from Pyrrosia longifolia (Burm. f.) C.V. Morton with antibacterial activity
Authors: Teruna Hilwan Yuda , Khodijah Rohimatul , Frimayanti Neni , Hendra Rudi
Published: December 2024

Background and purpose:

Pyrrosia longifolia is one of the medicinal plants in Indonesia. However, it has received little attention regarding pharmacological properties and phytochemicals. This study aimed to isolate bioactive compounds and evaluate their antibacterial activities.

Experimental approach:

The secondary metabolites were isolated using a bioassay-guided approach. The aerial part was macerated in methanol and the crude methanol was partitioned with organic solvents to obtain n-hexane, dichloromethane, ethyl acetate, and water extracts. The ethyl acetate extract was purified using chromatography procedures, yielding six chemicals, and their structures were determined using spectroscopy. The antibacterial activity of the compounds was evaluated.

Findings/Results:

Six secondary phytochemical metabolites were identified including naringin (1), catechin (2), quercetin (3), rutin (4), kaempferol (5), and mangiferin (6). The absolute configurations of compounds 1 and 2 were ascertained using electronic circular dichroism as 2S for naringin and 2R, 3S for catechin. The compounds exhibited antibacterial activity against several pathogenic bacteria, with MIC and MBC values ranging from 7.8 to 250 μg/mL. Computational investigations of these compounds revealed a substantial affinity for bacterial receptors’ active and allosteric regions. Furthermore, rutin exhibited the capacity to reduce the activity of β-ketoacyl-acyl carrier protein synthase III, enhancing its antibacterial effectiveness.

Conclusion and implications:

The in-vitro assessment revealed that the six identified compounds possess a wide range of antibacterial activity, which was corroborated by in-silico analyses. However, further investigation is required to back up the conclusion of this study.
MicroRNA-219 in the central nervous system: a potential theranostic approach
Authors: Shamaeizadeh Nahal , Mirian Mina
Published: December 2024

Despite the recent therapeutic advances in neurological disorders, curative therapy remains a serious challenge in many cases. Even though recent years have witnessed the development of gene therapy from among the different therapeutic approaches affecting pathophysiological mechanisms, intriguing aspects exist regarding the effectiveness, safety, and mechanism of action of gene therapies. Micro ribonucleic acid (microRNA-miRNA), as a fundamental gene regulator, regulates messenger ribonucleic acid (mRNA) by directly binding through the 3′-untranslated region (3′-UTR). MicroRNA-219 is a specific brain-enriched miRNA associated with neurodevelopmental disorders that play crucial roles in the differentiation of oligodendrocyte progenitorcells, promotion of oligodendrocyte maturation, remyelination, and cognitive functions to the extent that it can be considered a potential therapeutic option for demyelination in multiple sclerosis and spinal cord injury and reverse chronic inflammation pains. Additionally, miR-219 regulates the circadian clock, influencing the duration of the circadian clock period. This regulation can impact mood stability and is associated with phase fluctuations in bipolar patients. Furthermore, miR-219 also plays a role in modulating tau toxicity, which is relevant to the pathophysiology of Alzheimer’s disease and schizophrenia. Finally, it reportedly has protective effects against seizures and Parkinson’s disease, as well as neoplasms, by inhibiting proliferation, suppressing invasion, and inducing cell death in tumor cells. Exploring the miR-219 molecular pathways and their therapeutic effects on central nervous system disorders and the mechanisms involved, the present review study aims to illustrate how this information may change the future of gene therapy.
Synthesis, docking, pharmacokinetic prediction, and acetylcholinesterase inhibitory evaluation of N-(2-(piperidine-1-yl)ethyl)benzamide derivatives as potential anti-Alzheimer agents
Authors: Mohammadi-Farani Ahmad , Moradi Farzaneh , Hosseini Amin , Aliabadi Alireza
Published: December 2024

Background and purpose:

Alzheimer’s disease is the most common form of dementia and the sixth most common cause of death in the US according to the Alzheimer’s Association. As regards, to date, no effective treatments are available because of the multifactorial nature of the disease, therefore, a large body of recent research has been allocated to the design and development of multi-target-directed ligands that can become effective drug candidates.

Experimental approach:

A novel series of benzamide derivatives (5a-5l) containing piperidine core were synthesized in the current work. After identification of the chemical structures of the members of this series using 1H NMR, IR, and MS spectra, their anti-acetylcholinesterase activity was assessed by the Ellman᾽s test. Docking studies were also performed to investigate the binding mode and determine the interacting amino acids with the corresponding ligands. Finally, the pharmacokinetic (ADME parameters) of the most potent derivative (5d) was predicted and compared with donepezil.

Findings/Results:

Compound 5d possessing the fluorine atom substitution at position ortho was the most active compound in these series (IC50 = 13 ± 2.1 nM). This compound demonstrated superior activity than the reference drug donepezil (IC50 = 0.6 ± 0.05 µM). Molecular docking showed a significant hydrogen bonding of the carbonyl group of compounds 5d with tyrosine 121 into the active site of acetylcholinesterase. Fortunately, this compound showed better promising ADME properties than donepezil.

Conclusion and implication:

The benzamide derivatives introduced in this paper could be proposed as potential anti-acetylcholinesterase.
Ultra-small phospholipid nanoparticles in the treatment of combined hyperlipidemia: a randomized placebo-controlled clinical trial
Authors: Archakov Alexander , Kukharchuk Valery , Lisitsa Andrey , Ponomarenko Elena , Romashova Yulia , Pleshakova Tatiana , Yarovaya Elena , Kutsenko Vladimir , Guseva Maria , Beregovykh Valery , Ipatova Olga , Zubareva Marina , Tikhonova Elena , Ivanov Sergei , Bedretdinov Farid , Markin Sergey
Published: December 2024

Background and purpose:

Combined hyperlipidemia is associated with an increased risk of cardiovascular events. This clinical trial investigated phospholipovit (essential phospholipids, Institute of Biomedical Chemistry, Moscow, Russia), an ultra-small phospholipid nanoparticle (micelles), targeted to phospholipids of HDL in lowering non-HDL-cholesterol (non-HDL-C) and triglycerides (TG) levels in patients with combined hyperlipidemia and moderate cardiovascular risk.

Experimental approach:

A randomized, double-blinded, placebo-controlled phase II trial was conducted on 100 patients. Phospholipovit or placebo was randomly administered orally (500 mg) 2 times a day for 12 weeks. The primary endpoint was the percent change of non-HDL-C from baseline to 12 weeks of exposure.

Findings/Results:

Treatment with phospholipovit resulted in a mean non-HDL-C reduction of 13.2% versus 4.3% compared with placebo. The absolute decrease in non-HDL-C was -23.2 (-48.7 - 7.0) mg/dL versus -7.3 (-17.0 - 12.0) mg/dL, significantly. The therapeutic target of non-HDL-C less than 130 mg/dL (3.4 mmol) was achieved in 15 of 39 patients (38.5%) in the phospholipovit group versus 2 of 41 patients (4.9%) in the placebo group OR 11.8 (2.4 - 116). Significant reduction in TG, apolipoprotein B, total cholesterol, and very low-density lipoprotein cholesterol levels was also observed. There were no changes in the liver and kidney functions, vital signs, or electrocardiography. There were no serious adverse events.

Conclusion and implications:

Phospholipovit significantly reduced non-HDL-C, TG, and atherogenic lipoproteins in patients with combined hyperlipidemia and moderate cardiovascular risk. It can be used as an add-on therapy to statins.
A blind navigation guide model for obstacle avoidance using distance vision estimation based YOLO-V8n
Authors: CHIDI EBERE , Edward Anoliefo  , Collins Udanor  , Asogwa Tochukwu Chijindu  , Lois Onyejere Nwobodo
Published: December 2024

Obstacle is an object positioned along a path of propagation with the potential to cause a collision and hence, an accident. Over the years, several papers have applied advanced computer vision techniques, particularly transfer learning algorithms, to solve this problem, but despite their success, in specific vision applications such as blind guide navigation systems, the model finds it difficult to distinguish between objects and obstacles recognized in the same video frame, hence attracting research attention. In this paper, the aim was to develop a blind navigation guide model for obstacle avoidance using distance vision estimation-based YOLO-V8n. To achieve this, an improved data model was developed using the MS COCO dataset and primary data collected from several indoor environments. Then, the YOLO-V8n architecture was improved by adding a Weighted Feature Enhancement (WFE) model to the backbone for improved feature extraction, and Bi-directional Feature Pyramid Network (Bi-FPN) was applied to the neck to improve multi-scale feature representation. In addition, a Distance Vision Estimation (DVE) algorithm was developed and applied to the Bi-FPN before connecting it to the head of the YOLO-V8n to facilitate simultaneous object detection and distance measurement in real-time video. Furthermore, the issue of bounding box overlap in the model was addressed by applying a Wise Intersection over Unit (WIoU) loss function. Collectively, these formulated the new transfer learning algorithm called YOLO-V8n+WFE+Bi-FPN+DVE+WIoU used in this work for high-level obstacle detection and distance estimation. The model was trained considering different experimental architectures of the YOLO-V8 and loss functions, respectively, and then evaluated with precision, recall, mean absolute precision, and average precision, respectively, before validation through comparative analysis. Upon selection of the best model, it was further validated through comparison with other state-of-the art algorithms before deployment for obstacle avoidance in an indoor environment, having satisfied the condition of reliability. Real world testing of the model was performed at four different indoor sites, and the results showed that while the model was able to correctly classify objects, it could also measure their distance accurately, thereby making it suitable for deployment as a blind vision guide navigation system.
Pedagogía indígena: Un modelo integrador
Authors: Lara Lara José Aecio
Published: December 2024

El presente libro es el producto de una investigación amplia llevada a cabo por el Dr. José Alecio Lara, Director del Instituto Pedagógico Rural El Mácaro Luis Fermín de la Universidad Pedagógica Experimental Libertador.
Este docente Jivi se ocupó de indagar sobre las formas propias de cómo estos pueblos han transmitido y perpetuado sus conocimientos ancestrales. Específicamente, aborda aspectos referidos a quién le corresponde el rol de enseñar, en qué espacios y qué responsabilidades sociales se asignan tácitamente según el género. Todo ello como una vía para instaurar lazos entre la educación propia y la educación nacional, de manera que se concilie lo explicitado en dos leyes fundamentales.
Por ejemplo, en la Ley Orgánica para la Protección del niño y adolescentes (1998), cuyo art. 36 sobre los derechos culturales de las minorías establece que “Todos los niños y adolescentes tienen derecho a tener su propia vida cultural, a profesar y practicar su propia religión o creencias y a emplear su propio idioma, especialmente aquéllos pertenecientes a minorías étnicas, religiosas, lingüísticas o indígenas.” Asimismo, en el art. 60, se señala que “El Estado debe garantizar a todos los niños y adolescentes indígenas regímenes, planes y programas… acceso a los conocimientos generados por su propio grupo o cultura.” En consonancia con ello, la Ley Orgánica de Pueblos Indígenas (2005), en su art. 75, declara: “la educación propia de los pueblos y comunidades indígenas está basada en los sistemas de socialización de cada pueblo y comunidad indígena, mediante los cuales se transmiten y renuevan los elementos constitutivos de su cultura.”
Para el autor, esta investigación responde a un compromiso ético por su condición de padre y docente indígena preocupado por develar las estrategias propias para enseñar y aprender de tres pueblos amazonenses (Jivi, huottojä y Baniva), a fin de propiciar en los actores involucrados transformaciones sustantivas que favorezcan una educación apropiada.
Cumhuriyet Döneminde Toplumsal Değişim ve Din: Etkileşimler ve Dönüşümler
Authors: Akduman Abdil , Arı Yılmaz
Published: December 2024

Toplumsal değişim ve din, sosyal bilimlerin temel araştırma alanlarından biridir. Bu makale, bu iki kavramı Cumhuriyet Dönemi bağlamında incelemektedir. Cumhuriyet’in ilanıyla birlikte, Türkiye’de yeni bir toplum inşa etme çabaları ön plana çıkmıştır. Cumhuriyet öncesi dönemde din, toplumun ve yönetimin merkezinde yer alırken, Cumhuriyet’in laikliği benimsemesiyle birlikte dinin etkisi önemli ölçüde azalmıştır. Bu değişim, devlet politikaları aracılığıyla gerçekleştirilmiştir. Çalışma, Cumhuriyet’in ilanından 1982 Anayasası’nın kabulüne kadar olan dönemi kapsamaktadır ve bu süreçteki siyasi, dini ve sosyal değişimleri bütüncül bir yaklaşımla ele almaktadır. Laikliğin ilanı, eğitimde birlik sağlama, tekke ve zaviyelerin kapatılması, medeni kanunlarda yapılan reformlar ve kılık kıyafet düzenlemeleri gibi değişiklikler, toplumun yapısını önemli ölçüde etkilemiştir. Özellikle Diyanet İşleri Başkanlığı’nın kurulması ve bu kurumun günümüze kadar devam eden varlığı, her dönem tartışma konusu olmuştur. Bu çalışmanın odak noktalarından biri, bu başkanlığın devletin laik düzen içerisinde niçin kurulduğu ve toplumda hangi fonksiyonları yerine getirdiği sorusudur. Ayrıca, 1961 ve 1982 yıllarında çıkarılan anayasalar arasındaki değişimler de ele alınmış, bu süre zarfında toplumda meydana gelen dönüşümler detaylandırılmıştır. Nitel araştırma yöntemlerinden biri olan doküman analizi tekniği ile gerçekleştirilen bu çalışma, Cumhuriyet dönemi üzerine çok yönlü araştırmalara kaynak oluşturmayı ve alana katkı sağlamayı amaçlamaktadır. Toplumun din ile ilişkisi, laiklik politikaları ve bunların toplumsal etkileri üzerine kapsamlı bir anlayış geliştirmek, bu çalışmanın temel hedefidir.
ASHTAVIDHA SHASTRA KARMA IN PRASUTI TANTRA AND STREE ROGA IN SURGICAL PRACTICES IN PRESENT ERA W.S.R. TO AYURVEDA SHALYA KARMA
Authors: Udaipure Diksha , K Aswathy , Ray Sucheta , Hajare Priyanka
Published: December 2024

Ashtavidha Shastra karmas are the procedures or steps that are always the soul of all surgery because these are the
things that are generally the objectives of any surgery. With a broad vision, Ashtavidha Shastra karma may be
taken as the base of modern surgery, and that may be the reason why Ayurvedic and modern surgeons still remember Acharya Sushruta. Modern Surgery was not in practice before the 18th Century. It was developed after
Anesthesia & antibiotics. Ayurvedic Surgery (Shalya, Shalakya and Prasuti) was fully developed before the 10th
Century. Ayurvedic Surgery declined due to Sociopolitical reasons. Ashtavidha Shastra Karma’s principles of
eight basic surgical procedures are being used in day-to-day surgery, and many advancements have been made in
modern surgery regarding the development of minor surgical instruments to Robotic surgery. But the principles of
surgical treatment remain the same even today. In Prasuti Tantra Evum Stree Roga, shalya chikitsa involves surgical and pre-surgical interventions, and Astavidh shastra is one among them. The eight shalya karma is explained and used to treat many Prasuti Tantra Evum Stree Roga diseases. In the present scenario also, these eight
shastra karma are modified and are currently used in modern surgical science for surgical disorders, through article we want to elaborate on the ashtavidha shastra karma use in Prasuti Tantra Evum Stree Roga is the same as
today’s surgical procedures of modern.1
CONCEPTUAL UNDERSTANDING OF AVATARANA OF AATMA AND GARBHA
Authors: Narayan Ashwath , Murthy Mamata , Hegde Shruti
Published: December 2024

Concepts of Aatma and Garbha are intricate and exciting, which fascinated the Indian philosophers, who gave
elaborate descriptions with varied opinions. Ayurveda uniquely defines Aatma and Garbha wherein, Aatma is an
entity which are Anadi and Ananta solely responsible for all the lively activities of the Shareera, and Garbha, a
conglomeration of Panchabhoutika entities (Shukra and Shonita with Chetana). The Avatarana or Avakranti of
Aatma happens during Shukra and Shonita Samyoga to endure the Karmaphala and get liberated from the life-death
cycle. This happens along with Saatvika, Rajasika and Tamasika bhavas under the influence of Vayu Mahabhuta.
The event of Avatarana is fully under the control of Daiva and beyond appreciation with our perception. This study
attempts to understand the concepts of Aatma and Garbha and their Avatarana as mentioned in the texts of Ayurveda.
A CONCEPTUAL STUDY ON RAKTASTHAMBHANA AGADA YOGAS MEN-TIONED IN THE CONTEXT OF MAṆḌALIVIṢA W.S.R TO PRAYŌGASAMUCCAYAM
Authors: N M Swathykrishna , Aboobaker P A
Published: December 2024

In Agadatantra, haematological toxicities are dealt with in Maṇḍali viṣa. Maṇḍali is one among the type of saviṣa
saṛpas. Multiple complications may occur following Maṇḍali viṣa. They are haemorrhage, bleeding from the
mouth, eye, ear, nose, gum, hair follicles and stomach, rakta atisara, blood in urine and wound, Adho rakta etc.
These treatments include both external procedures and internal administration. Snake venom is the most complex
of all natural venoms. Venom-induced consumption coagulopathy (VICC) is a condition associated with hemotoxic
snake bites. Hemorrhage is the major symptom of systemic viper poisoning. Various Raktasthambhana yogas have
been told to manage bleeding in Prayōgasamuccayam. This paper attempts to review the Raktasthambhana agada
yogas mentioned in the Mandali viṣa chikitsa chapter of Prayōgasamuccayam.