bluuebunny/crossref_metadata_2025 huggingface dataset:
PENERAPAN TEKNOLOGI AUGMENTED REALITY PADA APLIKASI KATALOG PERUMAHAN BERBASIS ANDROID
Authors: Alam Bangkit Fajar Nur
Published: December 2022

Bisnis properti saat ini memang sedang menjamur dikota-kota besar dan kecil karena mempunyai keuntungan yang cukup besar. Augmented Reality (AR) adalah salah satu perkembangan teknologi saat ini. Augmented Reality (AR) adalah suatu lingkungan yang memasukkan objek virtual 3D kedalam lingkungan nyata secara real-time. Penelitian ini akan memasukkan teknologi AR kedalam katalog penjualan rumah pada Perumahan Pelangi Permata Residence, sehingga katalog rumah ini menjadi lebih nyata dengan adanya objek 3D. Aplikasi ini merupakan aplikasi yang berjalan pada teknologi sistem operasi android, dimana aplikasi AR ini memerlukan video streaming yang diambil dari kamera smartphone sebagai sumber masukan, kemudian aplikasi ini akan melacak dan mendeteksi marker dengan menggunakan sistem tracking, setelah marker terdeteksi, model rumah 3D pada katalog akan muncul diatas marker seolah-olah model rumah tersebut nyata. Aplikasi ini memberikan banyak informasi mengenai Perumahan, diantaranya spesifikasi bangunan, objek 3D rumah yang ditawarkan dan rendering objek. sehingga dengan bantuan aplikasi ini tugas bagian pemasaran akan menjadi lebih ringan dan mudah dalam penyampaian informasi mengenai perumahan yang ditawarkan. Dengan adanya aplikasi ini diharapkan akan terjadi peningkatan minat pembeli terhadap rumah yang ditawarkan oleh pengelola Perumahan Pelangi Permata Residence.
Knowledge, Attitude and Willingness to Participate in Gamete Donation for Artificial Insemination among Undergraduate Students in Lagos
Authors: Bakare OQ , Oluwole OE , Ogunkoya D , Aja C , Thomas J
Published: December 2022

Background: Infertility affects one-fifth to one-sixth of couples of reproductive age. Gamete donation is one option for managing infertility, but it is relatively unknown in the developing world.
Objectives: To assess Nigerian undergraduate students' knowledge, attitude and willingness to participate in gamete donation for artificial insemination.
Methods: A descriptive cross-sectional study was conducted among 160 undergraduate students using a semi-structured self-administered questionnaire. The respondents were recruited using a multi-stage sampling technique.
Results: The mean age of the respondents was 21.5±3.2 years, with a range of 18-32 years. The majority (89.4%) of the respondents were single and were in the first year of study (56.3%). Almost all the respondents (96.3%) had heard about the practice of gamete donation, but only (38.7%) had overall good knowledge about it. Almost half (46.9%) of respondents had an overall positive attitude towards gamete donation, while only 37.5% were willing to participate. The class level of the respondents (p = 0.03) was significantly associated with poor knowledge of gamete donation, while age (p = 0.01) and gender (p < 0.001) were associated with a negative attitude. Age (p<0.001) was also significantly associated with poor willingness to participate.
Conclusion: The respondents' awareness of gamete donation was high, but their knowledge was poor, leading to a negative attitude and poor willingness to participate. Public enlightenment on gamete donation for artificial insemination should be intensified.
Paediatric Gastrointestinal Endoscopy in a Nigerian Tertiary Hospital
Authors: Atimati AO , Ewah-Odiase RO , Irowa OO
Published: December 2022

Background: Gastrointestinal endoscopy is a very useful tool in the diagnosis and treatment of gastrointestinal disorders. Gastrointestinal endoscopy in paediatric practice is still evolving in Nigeria.
Objective: To determine the common indications for paediatric endoscopy in a Nigerian tertiary hospital.
Method: This was a retrospective study of all gastrointestinal endoscopic procedures performed for children aged 0 -18 years between January 2021 and March 2022. The hospital records of the children were retrieved, and data were extracted for analysis.
Results: Thirty-seven endoscopic procedures were performed on 32 children with two subjects having repeated procedures while one had both upper and lower gastrointestinal endoscopic studies. The mean age of the children was 11 ± 5.4 years with those aged between 10 and 14 years constituting the majority (40.6%). Most indications were diagnostic and the commonest indication for endoscopy was upper abdominal pain (40.6%) which was followed by upper gastrointestinal bleeding (37.6%). The endoscopic findings were mainly gastritis (56.8%), hiatus hernia (32.4%) and duodenitis (18.9%). The commonest therapeutic indication for gastrointestinal endoscopy was variceal banding.
Conclusion: Paediatric gastrointestinal endoscopy is useful for the diagnosis and treatment of paediatric gastrointestinal disorders. Upper abdominal pain and upper gastrointestinal bleeding are the leading indications for paediatric gastrointestinal endoscopy in Nigeria.
Relationship Between Subchorionic Haematoma and Abdominal Massage in Pregnancy in the Niger Delta Region of Nigeria: A Pilot Study
Authors: Kiridi EK , Oriji PC , Okechukwu C , Briggs DC , Ugwoegbu JU , Ubom AE , Addah AO , Abasi IJ , Bosrotsi PY , Adesina AD
Published: December 2022

Background: Abdominal massage (AM) in pregnancy is a common practice in the Niger Delta region of Nigeria. AM may cause events such as subchorionic haematoma (SAH) and increase the risk of miscarriages and adverse maternal and perinatal outcomes.
Objective: To determine the relationship between AM and SCH in the Niger Delta region of Nigeria.
Methods: A cross-sectional study was conducted from January to June 2022 at the Obstetrics and Radiology Units of four health facilities in Bayelsa State, Nigeria. Consenting eligible pregnant women presenting to the antenatal clinic during the first trimester were consecutively included. An obstetric ultrasound scan was performed transabdominal.
Results: Of the 403 women recruited, 241 (59.8%) were aged (20 – 29 years). The mean age was 28.02 ± 5.99 years. The mean body mass index was 23.82±4.60 kg/m2. While 170 (42.2%) had undergone AM in the first trimester of the index pregnancy, 126 (31.3%) had vaginal bleeding, and SCH occurred in 109 (27.0%) women. Women who had AM had 210 (CI: 58 – 878) times the odds of having SCH and 3.3 (CI: 2.14 – 5.15) times the odds of vaginal bleeding than women who did not have AM. Only 2 (1.8%) women with SCH did not have AM.
Conclusion: There exists a strong association between the occurrence of SCH among pregnant women who have had AM. More health education is needed for women in the Niger Delta region and Nigeria to eradicate the archaic practice and improve pregnancy outcomes.
Influencia de la protección del derecho de propiedad intelectual en la solución de problemas ambientales en la Unión Europea y en todo el mundo
Authors: Troitskiy Vladimir
Published: December 2022

Los límites sobre la protección de los derechos de propiedad intelectual son un tema de extenso debate. La extensión continua de la protección de los derechos de autor, que en algunas jurisdicciones (por ejemplo, en México, Honduras, Guatemala, Cote d’Ivoire) dura 75 años o más después de la muerte del autor, y donde los beneficiarios no son los autores sino probablemente la tercera generación de herederos, es ampliamente criticada. En el siguiente artículo se estudian casos en los que las leyes y regulaciones sobre la propiedad intelectual pueden considerarse como impedimentos potenciales para el intercambio internacional de datos climáticos y, por lo tanto, para la cooperación internacional en la búsqueda por resolver problemas ecológicos y climáticos a nivel mundial. Con el desarrollo de la ciencia y uso amplio de tecnologías avanzadas como blockchain o inteligencia artificial para recopilación y procesamiento de datos climáticos, el acceso libre y legal a la información se convierte en una condición necesaria para la resolución de problemas de medio ambiente. Esto se convierte en el principal campo de batalla, donde los intereses privados de los fabricantes de bases de datos y el interés público de la comunidad científica y ecológica entran en conflicto.
El régimen legal del registro de drones: la seguridad jurídica
Authors: Salinas González Claudio Arnaldo Manuel
Published: December 2022

El trabajo de investigación realizado tiene como tema específico y objetivo estudiar el registro de drones en la República del Paraguay, se analizó con precisión la situación planteada, haciendo uso de la doctrina, así como de una interpretación de las normas que se encuentran vigentes. Se verificó igualmente sobre las distintas situaciones que se pueden presentar, considerando la utilidad y funciones que ostentan dichos vehículos aéreos no tripulados para así determinar los efectos del registro de drones; y, también, se procedió a examinar cuál es el régimen jurídico que regula precisamente dicha inscripción, considerando las normas civiles y penales, en base a la responsabilidad y al daño, al tratarse de un tipo de registro muy moderno. Se abordan los principios registrales, de manera que pueda encuadrarse a la matriculación de los drones, pues se considera la radical importancia que tiene el acto registral, logrando garantizar plenamente la seguridad jurídica, la cual se configura como una necesidad fundamental para el hombre en sociedad. El proceso metodológico utilizado es el de la revisión bibliográfica, de tipo descriptivo. Se resalta, conclusivamente, que los efectos y consecuencias producidas por la inscripción registral son un alto valor jurídico-social, por lo cual se insta a promover una mayor legislación al respecto, enfatizar en las responsabilidades de la institución encargada de su control, mediante la aplicación más estricta de los requisitos para operar dichos vehículos aéreos no tripulados.
Percepción de un futuro significativo y autoconcepto en jóvenes estudiantes universitarios
Authors: Molina María Fernanda , Iribarne Karina , Alvarez Iturain Analía
Published: December 2022

La forma en que los jóvenes se proyectan en el futuro es crucial para un desarrollo positivo y la continuidad de sus estudios universitarios. Este trabajo se propone analizar la relación entre el autoconcepto actual y la percepción de un futuro significativo, expresada en su percepción de sí mismos en el futuro y el sentido de propósito vital (PV), en jóvenes que inician sus estudios universitarios. Participaron estudiantes (n = 173), de ambos sexos, que asisten a una universidad privada de la Ciudad Autónoma de Buenos Aires. Los estudiantes respondieron un Cuestionario sociodemográfico, el Perfil de Autopercepción para Estudiantes Universitarios, la Escala de claridad en el autoconcepto, el Cuestionario de los posibles sí mismos (PSs), y la Escala de propósito vital para jóvenes. Se encontró que las autopercepciones de dominio específico y la claridad en el autoconcepto son predictores de la probabilidad de alcanzar sus PSs deseados, y la búsqueda e identificación de PV. La autoestima global media estas relaciones. Este conocimiento permite pensar intervenciones destinadas a trabajar en el PV y los PSs de los estudiantes para aumentar su motivación y compromiso.
Aplicación de estrategias didácticas en el mejoramiento del aprendizaje en estudiantes del bachillerato
Authors: Balderas Cruz Jorge Alberto
Published: December 2022

La práctica educativa requiere de la aplicación de distintas estrategias para abordar el proceso enseñanza- aprendizaje, en este trabajo se buscó demostrar que la aplicación de estrategias didácticas favorece el proceso enseñanza-aprendizaje en el bachillerato. Se abordan además un conjunto de experiencias del autor en el trabajo con alumnos del bachillerato que favorecen el aprendizaje de los estudiantes. Para el desarrollo de este trabajo se tomaron en cuenta los resultados emanados de las evaluaciones docentes que realiza el departamento de planeación y calidad de la Universidad del Noreste, los que reflejaron la necesidad de potencializar las actividades aplicadas y mantener la diversificación de estas. Lo anterior se fundamenta utilizando un diseño de investigación no experimental y longitudinal que permitió demostrar la evolución de la aplicación de estrategias didácticas por parte del docente, se utilizaron como técnicas la encuesta, la observación y la indagación, los datos se recolectaron a través de encuestas que fueron formularios de Google, como participantes se consideran a los alumnos (24) y al docente que aplica las estrategias, se utilizó un muestreo por conveniencia. Si se considera que las actuales condiciones de la educación nos imponen transitar de un modelo o metodología presencial a uno híbrido resulta relevante que diversifiquemos la aplicación de estrategias didácticas. También se aborda la importancia que representa el aplicar distintas estrategias didácticas que faciliten y mejoren el aprendizaje en los alumnos. Por lo antes señalado el objetivo del presente trabajo es Exponer que con la aplicación de diversas estrategias constructivistas se favorece el proceso enseñanza-aprendizaje en los estudiantes de bachillerato.
Evaluation Of Morbid Obese Patients In Terms Of Sexual Dysfunctions: A Cross-Sectional Study
Authors: YAPRAK Bülent , ŞAHİN İbrahim , EVREN Bahri , KESKİN Lezzan , GÖNENİR ERBAY Lale
Published: December 2022

Aim: Obesity is a risk factor for sexual dysfunction. The aim of this study was to determine the frequency of sexual dysfunction in patients diagnosed with morbid obesity.Methods: The patient group included in the study consisted of 78 morbidly obese patients with BMI≥40 kg/m2 and 68 healthy individuals with normal BMI. The data were obtained by using the sociodemographic information form filled by the participants, Beck anxiety scale, Beck depression scale and Golombok Rust Sexual Satisfaction Inventory.Results: Obese individuals were found to have sexual dysfunction compared to individuals with normal body BMI (p<0.05). When the Golombok Rust subscale scores of obese men were compared to those of normal-weight individuals, a significant deterioration was found in all subscale scores, including frequency, communication, satisfaction, avoidance, touch, impotence and premature ejaculation. In addition, the anxiety and depression scores of obese individuals were shown to be higher than those of normal-weight individuals (p<0.05).Conclusion: Morbidly obese individuals should be evaluated in terms of sexual functions. We believe that regulating obesity treatment, including possible treatment for sexual dysfunction, will increase the success rate and enhance the quality of life for patients.
Gender differences in patients undergoing transcatheter aortic valve replacement: a cross-sectional study
Authors: AKTAN Adem , ERTAŞ Faruk
Published: December 2022

Aim: Transcatheter aortic valve replacement (TAVR) is an effective treatment modality for patients with high-risk symptomatic severe aortic stenosis (AS) who are not suitable for surgery. Gender-related differences in TAVR are still deliberated, thus in this study we aimed to investigate the effect of gender on clinical outcomes in patients who underwent TAVR in our clinic.Methods: 270 consecutive patients who underwent TAVR between January 2015 and January 2022 were included in the study. In addition to the patient's medical history, transthoracic or transesophageal echocardiography and computed tomography findings were examined to evaluate AS. Patients with symptomatic, high-risk severe aortic stenosis were treated with self-expanding Evolute-R devices. The patients were followed up for the first year after discharge. Follow-up was done by clinical visits and phone calls.Results: In-hospital mortality (5.4% vs. 7.4%; p=0.507), death at one-year follow-up (14.9% vs. 13.1%, p=0.681), and major adverse cardiovascular and cerebrovascular events (MACCE) at one-year follow-up (26.4% versus 23.8%, p =0.627) rates, there was no statistically significant difference between male and female genders. Kaplan Meier curves were used for survival analysis, including one-year mortality and MACCE rates. Accordingly, no statistically significant difference was found between the two genders in terms of mortality and MACCE (respectively; p= 0.910; p=0.889).Conclusion: In our patient group who underwent TAVR, we could not detect a significant difference in clinical outcomes between both genders. In recent years, the effect of gender on clinical outcomes may decrease with device and procedural developments.
Risk factors associated with mortality in patients with methanol poisoning: a retrospective study
Authors: AYDIN Hakan , DOĞANAY Fatih , ERDOĞAN Mehmet , DOĞAN Halil , BEŞTEMİR Attila , TUNCAR Alpay
Published: December 2022

Aim: Methanol poisoning (MP) is an significant medical problem worldwide, and despite advances in diagnosis and treatment, the mortality rate in these cases remains high. This study aimed to evaluate the clinical and laboratory factors to determine in-hospital mortality in patients with MP.Methods: This single-center, retrospective, observational study was conducted with 65 adult MP cases visiting the emergency department (ED) of a tertiary training and research hospital, between January 01, 2017 and February 01, 2022. Data was statistically compared between survivors and non-survivors.Results: The in-hospital mortality rate was 41.5%. The rate of cases with respiratory distress, low Glasgow coma scale (GCS) (≤8), and delayed arrival to the hospital (>24 hours) was higher in the group of non-survivors compared to the group of survivors. Non-survivors had a higher anion gap (30.5 mEq/L vs. 25.5mEq/L), base excess (-25.0 mmol/L vs. -18.6 mmol/L), lactate (10.2 mmol/L vs. 2.2 mmol/L) levels, and lower pH (6.76 vs. 7.14) and bicarbonate (6.3 mmol/L vs. 10.3 mmol/L) levels than survivors (p<0.001). In ROC analysis, pH (AUC= 0.916) and base excess (AUC=0.915) were blood gas parameters with the highest AUC values in predicting mortality in MP cases. Folate use in the treatment had a statistically significant effect on mortality (P=0.015).Conclusion: In MP cases, delay in a hospital visit, severe metabolic acidosis, high lactate levels, low GCS on arrival to the ED and no folate therapy, were associated with increased in-hospital mortality rates. Our data will contribute to the clinical management of MP patients and the development of treatment protocols.
Potential of oxazolidines and zirconium oxalate crosslinkers on the hydrothermal and thermo-mechanical stability of collagen fiber
Authors: Mahdi Ahmed Haroun  , Manal Mohammed Ahmed
Published: December 2022

Collagen, a unique connective tissue protein finds extensive application as prosthesis, artificial tissue, drug carrier, cosmetics and leather industry. This work has been undertaken to stabilize collagen using oxazolidine and zirconium oxalate as crosslinking agents. It has been found that both oxazolidine and zirconium oxalate imparts thermal stability to collagen, and oxazolidine exhibits a marked rise in the peak temperature when compared to both native and zirconium oxalate tanned collagen. On the other hand, zirconium does not seem to alter the tensile strength of collagen fibers significantly in wet condition as well as oxazolidine. The study is expected to enhance the biomaterial applications of collagen tissues.
Microbial profile of cabbage (Brassica oleraceae) sold in markets within Ibadan metropolis
Authors: Bukola Ayodeji Bamkefa  , Emeka Taye Umezurike  , Omolola Oluboyede  , Kehinde Adegbehingbe
Published: December 2022

Cabbage is a dietary source of micronutrients, vitamins and fiber, vital for human health. Cabbage samples for this study were obtained from selected markets in Ibadan, Nigeria. Serial dilutions and membrane filter techniques were used to determine microbial load and profile of the samples. Appropriate culture media and techniques were used to detect for the presence of Fungi and Bacteria in samples. Fungi isolated included; Sclerotinia sp, Fusarium sp, Cladosporium sp, Aspergillus sp, Mucor sp, Alternaria sp and Rhizopus sp. Bacteria isolated included; Staphylococcus sp, Pseudomonas sp, Xanthomonas sp, Micrococcus sp, Bacillus sp, Erwinia sp, and Streptococcus sp. The fungi load was highest in cabbage samples collected from challenge having 158.0 X 103 cfu/ml, followed by cabbage purchased from Bodija having 67.6 X 103 cfu/ml, Monatan 63.6 X 103 cfu/ml. , Oje 27.0 X 103 cfu/ml, and Gbagi 24.0 X 103 cfu/ml. The bacterial load on the cabbage samples was observed to be the highest in cabbage samples from Bodija with 360.0 X 103 cfu/ml, followed by samples from Gbagi 188.6 X 103 cfu/ml, Monatan 171.3 X 103 cfu/ml, Challenge 133.6 X 103 cfu/ml and Oje 85.3 X 103 cfu/ml. Results also showed that Ascetic Acid lowered microbial load and thus researchers recommend that cabbage be treated with 2.5 - 5% acetic acid (vinegar) for 5-10 minutes to reduce microbial load then rinse with sterile water before consumption. Enlightenment campaigns are necessary for vendors and people purchasing cabbage for consumption on the dangers of not washing before selling and consuming.
Characteristics of deafness in the elderly patients at Sanglah general hospital period march 2020-march 2021
Authors: Idola Pratiwi  , I Made Wiranadha
Published: December 2022

Introduction: Elderly is defined as an individual who has reached the age of 60 years and over. the number of elderly population in Indonesia currently reaches 28.7 million people, 10.6% of the total population of Indonesia. In 2020 Bali has entered the aging population, namely when the percentage aged 60 years and over reaches more than 10%. In line with the increasing life expectancy of people in Indonesia, health problems for the elderly will increase. One of the health problems of the elderly is hearing loss. Pathological changes in the hearing organ due to the degeneration process in the elderly can cause deafness. Objective: To determine the characteristics of deafness in elderly patients at Sanglah General Hospital during the period March 2020-March 2021. Methods: This study used a retrospective descriptive research design with cross sectional design, by taking secondary data from medical records of elderly patients with deafness who came to the ENT’s polyclinic at Sanglah General Hospital during the period March 2020-March 2021. Result: Characteristics deafness in elderly patients based on gender, the most found in male group compare to female group (53,3%: 46,5%), the largest age group was in the 60-70 years group as many as 33 people or 56.9%. Based on audiometric examination 39 elderly patients with deafness or 67.2% with sensorineural deafness. Characteristics based on the degree of deafness in elderly patients most found intensity in range between 56-70 dB, 20 people or 34.5% who experienced moderate deafness. The most common based on the side of the ear 53 people with deafness (91.4%) on both sides of the ear or bilateral. Conclusion: This study found that deafness in elderly patients is more commonly found in male, at age groups 60-70 years old with the most type of sensorineural deafness type, the most degree of deafness is moderate to severe degree, and deaf complaints on the both sides.
Trend of using herbal based preparations in pediatric skin inflammation disorders
Authors: Dorina Shengjergji Dervishi  , Emi Panariti  , Arnisa Nuna
Published: December 2022

Introduction: Skin inflammations that are more common and affect the pediatric age group more are rash, atopic dermatitis, fungal infections, psoriasis. The use of medicinal plants and herbal based preparations in the treatment of skin diseases, results from their impact on several stages of inflammation. The aim of this study was to review the information about the effects and anti-inflammatory activity, of medicinal plants and their preparations related to the treatment of most frequent skin inflammations in the pediatric age group, and to assess the trend of use of herbal remedies for these inflammations from our population. Methodology: For the realization of this descriptive and analytical study, multiple sources of information were used for the literature review, as well as through a random questionnaire conducted in a sample of 120 pharmacies in country. The data was collected from the pharmacists ‘responses and was analyzed specifically for the skin inflammations of pediatric age groups and the use of herbal preparations for the treatment of this disorders. Results: From the literature review the most frequent skin inflammations in the pediatric age group identified were rash, atopic dermatitis, fungal infections, folliculitis, furuncle, carbuncles. During the last years, among the medicinal plants mostly used locally for skin treatment are Matricaria Recutita, Calendula officinalis, Aloe Vera, Echinacea purpurea, Oenothera biennis, etc. From the completed questionnaire, a significant part of pharmacists (45%), reported that the most common skin inflammations in pediatric age presented in pharmacy are atopic dermatitis, rash for 17% of them, and fungal infections (12%). Regarding the way of using these preparations, 57% of them reported that they are used locally as combined therapy with the conventional one. Pharmacists reported that herbal preparations mostly used locally are those with Aloe Vera (31%), 13% of them reported those with Calendula officinalis and 5% of them reported preparations with Matricaria Recutita. Meanwhile, 48% of them reported that combined preparations of these herbs were used. Pharmacists are mostly the ones who suggest the use of these herbal based preparations (48.31%). Also, 65% of them think that the use of herbal based preparations for the treatment of skin inflammations in the pediatric age group has increased in recent years. Conclusions: Medicinal plants are rich with active ingredients and can be effective for the treatment of skin inflammations in the pediatric age group. As their use has increased in recent years, further research is needed regarding the efficacy, safety, optimal uses, and standardization of herbal preparations.
Cimetidine in the management of colorectal cancer: A survey of the knowledge and opinions of pharmacy students
Authors: Jocelyn Brown  , Bisrat Hailemeskel  , Fekadu Fullas
Published: December 2022

This survey was conducted at Howard University (HU) College of Pharmacy as part of a Drug Information course, in which First-Year Pharmacy students learn how to perform literature search on a pharmacy topic and run a survey. A total of 42 student respondents participated in the survey. Nearly 64% (n=27) wrongly thought that cimetidine reduces the risk of colon cancer, while 57.1% (n=24) gave a wrong response that, even though cimetidine is FDA-approved for other indications, it can be taken for the prevention of colorectal cancer. Twenty-seven (64.3%) correctly believed that cimetidine is used for other health problems than colorectal cancer. The majority gave the correct response (n=25; 59.5%) that prescription medications are more useful than dietary supplements for the prevention of colorectal cancer. The highest number of correct responses (n=28; 66.7%) was obtained for the question of cimetidine passing through breast milk. The opinions of survey respondents were evenly divided in recommending cimetidine for the prevention of colorectal cancer (50%, n=21), and knowing someone or oneself taken for other than colorectal cancer (50%, n=21). Opinions varied unevenly for the other three opinion-based questions.
Prioritizing metal detector for finished pharmaceutical formulation: Manufacturing safe, quality product
Authors: Ishita Sharma  , Kumud Upadhyay  , Sushil Giri
Published: December 2022

Background: The pharmaceutical metal detector is a device to detect metal as well as non-metal contaminants of large size in the pharmaceutical dosage form. The detection of unwanted metal (contaminant) is important to produce a high quality of the dosage form. Main body: Pharmaceutical dosage forms are highly sensitive to the environment to which they are surrounded. It is challenging to keep a product in its original form throughout its shelf life. These metals find entry in the pharmaceutical formulation during various phases of manufacturing while passing through pipelines, sieves, conveyors, wires, buds, error in mixing processes, through raw materials. The Food and Drug Administration Hazard Evaluation board has given that the length of 0.3 inches to 1 inch of metal is considered unacceptable. The article highlights source of the metal contamination in pharmaceutical formulation types of detectors used, FDA standard for the metal detector, the need for a metal detector with its ideal properties, effect, hazards of ingesting metal fragments through medicines, working principle, uses, separation of metal contamination, test for the metal detector go about when metal is detected. Monitoring of system in a metal detector at the Critical control points some case studies involve reputed pharmaceutical manufacturers, which were forced to recall the batches for metal fragments detected in finished product. Conclusion: The pharmaceutical companies are bounded to produce quality safe products. One adulteration may cause recalls of products, cost loss of millions of dollar or total disruption of business as well. The selection of suitable metal detector is much needed. As the metal detector inclusively controls the contamination maintains a tough control on the quality of products.
The clinical, laboratory and anatomical pathology profiles of Hashimoto’s Thyroiditis patients at Dr. Soetomo General Academic Hospital Surabaya 2015 – 2020
Authors: Shisilia Mitra Novita  , Rio Wironegoro  , Dyah Fauziah
Published: December 2022

The primary cause of hypothyroidism in the ​​sufficient iodine area is Hashimoto's thyroiditis. Hashimoto's thyroiditis, also known as chronic autoimmune thyroiditis or chronic lymphocytic thyroiditis, is an autoimmune condition in which B cells and T cells slowly destroy the thyroid gland. To determine the diagnosis, we need the clinical, laboratory, cytological, and/or histopathology profiles. It aims to distinguish Hashimoto's thyroiditis from other diseases such as nontoxic goiter and Graves' disease. This retrospective descriptive study used data from the medical record of Dr. Soetomo General Hospital from 2015-2020. This study used total sampling and got 18 patients in total. The patients were mostly females (n=15), in the age group of 40-49 years old (n=8). The main complaint was an enlargement or nodule in the neck. The TSH (thyroid stimulating hormone) levels were majorly higher than the normal range (n=8) meanwhile the FT4 levels were mostly normal (n=6) and low (n=6). The positivity of TPOAb (antibody against thyroid peroxidase) is merely found in one patient. The majority of the result of the Doppler ultrasound examinations revealed Hashimoto’s thyroiditis (n=7). FNAB (fine needle aspiration biopsy) was performed on 11 patients. A histopathology examination was also conducted on 9 patients who underwent thyroidectomy. All of the cytology and histopathology examinations confirmed Hashimoto’s thyroiditis. Non-Hodgkin Lymphoma was found to coexist with 2 Hashimoto's thyroiditis cases. The findings were similar to the previous studies, except that among all the subjects, those who are 40-49 in age were primarily found in this study.
Review on management of GERD
Authors: Pooja Rani  , Rajesh Asija  , Rashmi Khanijau
Published: December 2022

Gastroesophageal reflux disease (GERD) is a chronic disorder of the upper gastrointestinal tract with global distribution. The incidence is on the increase in different parts of the world. It is characterized by heartburn and/or regurgitation symptoms is one of the most common gastrointestinal disorders managed by gastroenterologists and primary care physicians. Optimization of therapy (improving compliance and timing of PPI doses), or increasing PPI dosage to twice daily in select circumstances, can reduce persistent symptoms. In patients with residual reflux, medications like H2 blockers, Prokinetics and baclofen may be used. In those with functional heartburn or reflux sensitivity neuro-modulators form an integral part of any therapeutic approach.
Improving the post-harvest shelf-life of Abelmoschus esculentus L. using NOP-1 Octapeptide
Authors: Chithra R  , Mathangi Ganapathy
Published: December 2022

Increasing the post-harvest shelf life of rapidly perishable vegetables is a daunting task. In the case of Abelmoschus esculentus L, pod hardening and browning of the pod ridges reduces its commercial value and nutritional worth. Different methods like, use of ethylene inhibitors like 1-methylcyclopropene (1-MCP), 1-Aminoethoxyvinylglycine (AVG); salt solutions like 1% and 2% calcium chloride (CaCl2) and application of synthetic peptide inhibitors are adopted to enhance the shelf life of rapidly perishable fruits, vegetables and flowers. This study aims to find out the efficacy of exogenous surface application of synthetically derived octapeptide NOP-1 (LKRYKRRL-NH2) treatment at concentration of 1000μM for retarding the rapid over-ripening in A. esculentus L. The A. esculentus L. pods were stored under two conditions, at ambient room temperature & at cold storage for stipulated duration. The total flavonoid, phenolic and anti-oxidant contents were investigated. It was observed that NOP-1 peptide treatment helped to maintain the quality of the pods under both ambient and cold temperatures up-to 8 days. Anti-senescence plant derived peptide (NOP-1) adopted for study was noticed to improve the storage stability in terms of maintaining the phytochemical compositions of A. esculentus L. pods. The possible mechanism could be the binding of NOP-1 peptide to the ethylene receptor (ETR-1) thus reducing ethylene perception and subsequently ethylene induced ripening. The concept is new and can be safely explored for FSSAI food regulations standards. The success of this study will give higher commercial value and prolonged shelf life for short shelf-life vegetables like Abelmoschus esculentus L.
Recent advancement in clinical diagnosis
Authors: Dikshita Medhi  , Swati Agarwal  , Dharitri Sharma  , Purushottam Kumar
Published: December 2022

Periodontitis is a chronic inflammatory condition of the tissues surrounding the tooth, associated with attachment loss. It is a series of events which starts from gingivitis and when remains untreated progresses to periodontitis. Traditional periodontal clinical diagnostic parameters which include probing depths, bleeding on probing, clinical attachment levels, plaque index, and radiographs are insufﬁcient for identifying sites of active diseases. Thus, advanced techniques like newer generation of periodontal probes, advances in microbiological analysis, immunodiagnostic techniques, molecular biology techniques, biomarkers and genetic testing will improve the identiﬁcation of gingivitis prior to the exhibition of symptoms of periodontitis.
Immature platelet fraction as predictor of platelet recovery in dengue fever
Authors: Luh Pradnya Ayu Dewantari  , I Gusti Nyoman Gde Bidura  , I Gusti Bagus Teguh Pramana
Published: December 2022

Dengue fever is caused by dengue virus—a mosquito-borne flavivirus and transmitted by Aedes aegypti and Aedes albopictus, and estimated 390 million cases of dengue infection occur each year globally, with 96 million cases being considered severe. Thrombocytopenia has always been one of the criteria used by WHO guidelines as a potential indicator of clinical severity. Thrombocytopenia is a common cause of concern in dengue to both patients and attending clinicians. To avoid hemorrhagic complications in dengue fever with thrombocytopenia, prophylactic platelet transfusions are administered. Even though it saves lives, platelet transfusions have their own dangers. In order to prevent unnecessary platelet transfusions, a lot of study has been done on Immature Platelet Fraction (IPF) as a predictor of platelet recovery. IPF is a measurement of reticulated platelets that represents the rate of thrombopoiesis. The rapid detection of IPF can lower the danger of platelet transfusion.
Keseimbangan Kehidupan-Kerja dan Kebahagiaan Di Tempat Kerja, Bagaimana Dampaknya Terhadap Organizational Citizenship Behavior (OCB) ?
Authors: Pratama Syamsul Huda , Sari Erita Yuliasesti Diah , Widiana Herlina Siwi
Published: December 2022

Organization citizenship behavior (OCB)  merupakan isu penting dalam organisasi untuk mencapai efektifitas dan efisiensi. Penelitian ini bertujuan untuk menguji pengaruh keseimbangan kehidupan-kerja dan kebahagiaan di tempat kerja terhadap OCB. Seratus tiga puluh orang guru dari beberapa SMK Muhammadiyah di Yogyakarta berpartisipasi dalam studi ini  Teknik sampling yang digunakan adalah teknik proportional sampling. Instrumen yang digunakan untuk pengumpulan data adalah skala OCB, skala keseimbangan kehidupan-kerja, dan skala kebahagiaan di tempat kerja. Teknik analisis data menggunakan  teknik analisis regresi linier berganda. Hasil penelitian menunjukkan, (1) keseimbangan kehidupan-kerja dan kebahagiaan di tempat kerja secara signifikan memengaruhi OCB, (2) keseimbangan kehidupan-kerja memiliki pengaruh  signifikan terhadap OCB, (3) kebahagiaan di tempat kerja memiliki pengaruh signifikan terhadap OCB. Kebahagiaan di tempat kerja memiliki sumbangan efektif sebesar 17,09% terhadap OCB, lebih besar daripada keseimbangan kehidupan-kerja sehingga diharapkan sekolah dapat memperhatikan kebahagiaan di tempat kerja untuk meningkatkan OCB guru.
Kepercayaan dan Keterpercayaan Pada Relasi Suami-Isteri Milenial Muslim
Authors: Shobihah Ida Fitri , Fathoni Achmad
Published: December 2022

Hubungan suami-isteri adalah hubungan yang harus dijaga dengan baik karena Islam mengajarkan dan memerintahkan demikian. Kepercayaan (trust) dan keterpercayaan (trustworthiness) menjadi bagian dari faktor penentu keberlangsung rumah tangga. Penelitian ini bertujuan untuk mengetahui lebih dalam bagaimana konsep dan dinamika trust dan trustworthiness dalam relasi pasangan suami isteri generasi milenial muslim. Melalui metode penelitian kualitatif dengan pendekatan contructive realism menunjukkan hasil bahwa trust dan trustworthiness merupakan dua aspek yang saling berkaitan dan mempengaruhi keutuhan rumah tangga yang dibangun oleh pasangan milenial muslim. Pasangan milenial muslim perlu membangun kepercayaan dan menjadi pasangan yang terpercaya diperlukan kepribadian baik, komunikasi terbuka, kemauan untuk percaya, tidak adanya permasalahan dan lama kebersamaan. Satu tindakan negatif seperti berbohong atau selingkuh dapat menyebabkan pasangan kurang percaya dan berpotensi menyebabkan munculnya masalah dalam hubungan suami istri.
TINGKAT KESEJAHTERAAN PSIKOLOGIS DITINJAU DARI TIPE KEPRIBADIAN BIG FIVE
Authors: Febriyanti Veny , Eva Nur , Andayani Sri
Published: December 2022

Penelitian ini bertujuan untuk mengidentifikasi perbedaan kesejahteraan psikologis antara lima tipe kepribadian utama. Sebuah tes yang berbeda menggunakan analisis statistik Kruskall-Wallis digunakan dalam penyelidikan ini. Skala Inventarisasi Lima Besar dan Skala Kesejahteraan Psikologis yang dimodifikasi digunakan dalam alat penelitian untuk mengukur Kepribadian Lima Besar. 84 partisipan dalam penelitian ini dipilih dengan teknik incidental sampling. Temuan mengungkapkan bahwa lima tipe kepribadian utama memiliki dampak besar pada kesejahteraan psikologis (Sig = 0,031 0,05). Faktor kepribadian dengan rata-rata kesejahteraan psikologis tertinggi adalah conscientiousness (43,70), sedangkan neurotisisme memiliki rata-rata kesejahteraan psikologis terendah (19,50).
ANALISIS PROPERTI PSIKOMETRI SKALA STUDENT ENGAGEMENT VERSI BAHASA INDONESIA
Authors: Pratama Mario , Guspa Anindra
Published: December 2022

Student engagement merupakan salah satu faktor yang berpengaruh terhadap prestasi akademik pelajar, namun banyak perdebatan mengenai defenisi operasional dan dimensionalitas dari konstruk ini. Penelitian ini bermaksud menguji secara psikometris konstruk ini. Sebanyak 596 pelajar di Indonesia berpartisipasi dalam penelitian ini yang teridiri dari siswa SMP, SMA, dan mahasiswa S1. Pengambilan data dilakukan secara online dengan menggunakan alat ukur  student engagement scale (SES) versi bahasa Indonesia adaptasi dari versi SES Reeve & Itseng berisi 22 item. Hasil uji properti psikometrik skala ini didapatkan bahwa koefesien reliabilitas Cronbach alfa sebesar 0,927. Analisis validitas isi dengan Forward-Backward translasion oleh ahli bahasa dan dengan penilaian panel ahli. Analisis validitas konstruk dengan analisis faktor menemukan bahwa SES versi bahasa Indonesia memiliki model fit 4 faktor. Hasil ini menunjukkan bahwa SES versi bahasa Indonesia memiliki struktur model yang identik dengan struktur model SES versi aslinya.
HUBUNGAN PERAN INTERNET DENGAN PERILAKU SEKSUAL REMAJA PADA MASA PANDEMI
Authors: Uleng Andi Tenri , Rahma Rahma , Seweng Arifin
Published: December 2022

Dampak pandemi terhadap kehidupan remaja yaitu remaja berpotensi adiksi internet akibat pesatnya perkembangan teknologi informasi. Perkembangan ini membuka peluang besar akses informasi baik itu positif maupun negatif, sehingga informasi sulit dikontrol cenderung membentuk perilaku seksual berisiko pada remaja. Penelitian ini bertujuan untuk mengetahui hubungan antara peran internet dengan perilaku seksual remaja. Desain penelitian yang digunakan adalah cross sectional study. Jumlah sampel sebanyak 305 orang dengan teknik pengambilan data yang digunakan adalah proportional random sampling. Penelitian dilakukan di SMK Negeri 1 Maros pada tanggal 14 Februari 2022-10 Maret 2022. Data dianalisis secara univariat dan bivariat dengan menggunakan uji chi-square. Hasil penelitian menunjukkan bahwa terdapat hubungan antara frekuensi (p=0,000), durasi (p=0,000), penggunaan internet (p=0,000), dan penggunaan media sosial (p=0,000), dengan perilaku seksual remaja. Hal ini menunjukkan bahwa semakin sering dan lama penggunaan internet, menyebabkan positifnya perilaku seksual berisiko. Serta, apabila penggunaan internet berkonten pornografi tinggi dan media sosial yang tidak sehat maka remaja memiliki kesempatan untuk melakukan perilaku seksual berisiko. Terdapat hubungan antara frekuensi, durasi, penggunaan internet, dan penggunaan media sosial dengan perilaku seksual remaja. Saran kepada remaja sebaiknya melakukan hal-hal positif diwaktu luangnya, sekolah memberikan materi pendidikan kesehatan reproduksi, dan orang tua lebih memperhatikan penanaman nilai-nilai kepada remaja.
HUBUNGAN MUTU PELAYANAN DENGAN KEPUASAN PASIEN BPJS RAWAT JALAN PUSKESMAS BIRU BONE
Authors: Oktavianti Devy , Indar Indar , Abadi Yusri
Published: December 2022

Mutu pelayanan pada Puskesmas menjadi salah satu faktor penting untuk menciptakan kepuasan pasien. Pelayanan yang berkualitas adalah memberikan pelayanan kepada pasien dan keluarganya sesuai standar kualitas untuk memenuhi kebutuhan dan keinginannya, sehingga dapat memperoleh kepuasan yang dapat meningkatkan kepercayaan pasien dan keluarganya terhadap Puskesmas. Penelitian ini bertujuan  mengetahui hubungan mutu pelayanan kesehatan dengan kepuasan pasien BPJS rawat jalan Puskesmas Biru Kabupaten Bone. Metode: Jenis penelitian ini adalah survei analitik dengan menggunakan pendekatan cross sectional study. Jumlah sampel sebanyak 100 orang responden yang diambil dari jumlah kunjungan pasien yang datang 3 bulan terakhir di Puskesmas Biru. Pengambilan sampel menggunakan metode accidental sampling. Analisis Bivariat antara variabel independen dan dependen ini menunjukkan bahwa variabel Akses terhadap pelayanan p=0,013 (p<0,05) memiliki hubungan antara mutu pelayanan kesehatan dengan kepuasan pasien BPJS rawat jalan di Puskesmas Biru. Variabel kenyamanan p=0,012 (p<0,05) juga memiliki hubungan antara mutu pelayanan kesehatan dengan kepuasan pasien BPJS rawat jalan di Puskesmas Biru. Sedangkan variabel yang tidak berhubungan antara mutu pelayanan kesehatan dengan kepuasan pasien BPJS rawat jalan di Puskesmas Biru yaitu variabel hubungan antar manusia p=0,361 (p>0,05) dan ketepatan waktu p= 0,170 (p>0,05). Ada hubungan antara akses terhadap pelayanan, kenyamanan dengan kepuasan pasien BPJS rawat jalan, tidak ada hubungan antara hubungan antar manusia, ketepatan waktu dengan kepuasan pasien BPJS rawat jalan. Hendaknya pihak Puskesmas lebih memperhatikan keluhan yang disampaikan oleh pasien seperti ketidaknyamanan yang dirasakan oleh pasien karena semua ini sangat berdampak terhadap mutu pelayanan kesehatan.
FAKTOR RISIKO STUNTING PADA BALITA DI PUSKESMAS TAMALATE KOTA MAKASSAR TAHUN 2022
Authors: Sanda Alfrida , Amiruddin Ridwan , Rismayanti Rismayanti
Published: December 2022

Stunting merupakan salah satu bentuk kegagalan dalam pengawasan pertumbuhan dan perkembangan anak yang ditandai dengan perawakan tubuh yang pendek (nilai z-score TB/U atau PB/U < -2 SD) yang dapat berdampak pada kerusakan fisik dan kognitif yang parah. Dinkes Kota Makassar tahun 2020 menyatakan prevalensi balita stunting di Puskesmas Tamalate sebesar 8,8%, berada di posisi ke 16 dari 46 puskesmas yang ada di Kota Makassar. Penelitian ini bertujuan untuk mengetahui faktor risiko kejadian stunting pada balita di Puskesmas Tamalate Kota Makassar tahun 2022. Jenis penelitian yang digunakan adalah observasional analitik dengan menggunakan desain studi Case Control. Populasi penelitian adalah semua balita yang berusia 0 - 59 bulan di Puskesmas Tamalate Kota Makassar tahun 2020 yaitu sebanyak 2.989 balita dengan jumlah sampel sebanyak 498 balita. Teknik pengambilan sampel kontrol yang digunakan dalam penelitian adalah simple random sampling. Adapun data dianalisis menggunakan SPSS secara univariat dan bivariat dengan melihat nilai p- value dan uji Odds Ratio. Hasil penelitian menunjukkan bahwa BBLR merupakan faktor risiko stunting pada balita (p-value < 0,05). Analisis BBLR menghasilkan nilai OR=2,737 (95%; CI=1,506–4,974). Analisis selanjutnya menunjukkan bahwa jenis kelamin tidak memiliki hubungan terhadap kejadian stunting pada balita dikarenakan p=0,612 (OR=0,908; 95%; CI=0,625–1,318).  Berat badan lahir bayi yang rendah (BBLR) merupakan faktor risiko terjadinya stunting pada balita sehingga perlunya upaya untuk menghindari risiko melalui asupan adekuat bagi ibu selama mengandung dan secara rutin memeriksakan kandungannya, olehnya hal ini juga perlu menjadi perhatian dari Puskesmas.
HUBUNGAN MUTU PELAYANAN KESEHATAN DENGAN KEPUASAN PASIEN BPJS PUSKESMAS PANGKAJENE
Authors: Khafifah Nurul , Razak Amran
Published: December 2022

Mutu pelayanan pada Puskesmas menjadi salah satu faktor penting untuk menciptakan kepuasan pasien. Pelayanan yang berkualitas dalam konteks pelayanan di puskesmas adalah memberikan pelayanan kepada pasien dan keluarganya sesuai standar kualitas untuk memenuhi kebutuhan dan keinginannya, sehingga dapat memperoleh kepuasan yang dapat meningkatkan kepercayaan pasien dan keluarganya terhadap Puskesmas. Penelitian ini bertujuan untuk mengetahui hubungan mutu pelayanan kesehatan dengan kepuasan pasien BPJS rawat jalan di Puskesmas Pangkajene Kab. Sidenreng Rappang di era normal baru ini. Jenis penelitian ini adalah survei analitik dengan menggunakan pendekatan cross sectional study. Jumlah sampel dalam penelitian ini adalah sebnayak 100 orang responden yang diambil dari jumlah kunjungan pasien yang datang mulai bulan Januari sampai dengan bulan November 2021 di puskesmas Pangkajene. Pengambilan sampel menggunakan metode accidental sampling. Hasil analisis bivariat antara variabel independen dan dependen menunjukkan bahwa variabel akses terhadap pelayanan p=0,016 (p<0,05) dan kenyamanan p=0,002 (p<0,05) memiliki hubungan antara mutu pelayanan kesehatan dengan kepuasan pasien BPJS rawat jalan di Puskesmas Pangkajene. Variabel yang tidak berhubungan antara mutu pelayanan kesehatan dengan kepuasan pasien BPJS rawat jalan di Puskesmas Pangkajene yaitu variabel hubungan antar manusia p=0,285 (p>0,05). Begitupun dengan variabel ketepatan waktu yang juga tidak berhubungan dengan kepuasan pasien p=0,189 (p>0,05). Oleh karena itu dapat disimpulkan bahwa ada pengaruh antara akses terhadap pelayanan, kenyamanan dengan kepuasan pasien, namun tidak ada pengaruh antara hubungan antar manusia, ketepatan waktu dengan kepuasan pasien. Diharapkan puskesmas lebih memperhatikan keluhan yang disampaikan oleh pasien dan mencari solusi untuk mengatasi persoalan agar kedepannya ada perubahan yang baik.