bluuebunny/crossref_metadata_2025 huggingface dataset:
Fulminant Myocarditis: A Very Rare Manifestation of Dengue Fever
Authors:   MD General Medicine, Senior Resident, Chettinad Hospital and Research Institute, Kelambakkam, Tamil Nadu, India, Harikrishnan Elackiya
Published: October 2022

Dengue is a highly prevalent arthropod-borne viral disease in tropical and subtropical areas of the globe. The majority of dengue cases are benign but rare complications and presentations are seen increasingly due to the rising burden of the disease mainly in tropical countries. In dengue, clinical manifestations vary from asymptomatic infection to severe disease. Dengue fever is characterised by fever, myalgia, arthralgia, headache and bleeding manifestations. We report a rare case of dengue fever complicated with acute myocarditis. The patient recovered gradually with supportive care.
A Preliminary Study on Parenteral Intravenous Iron Sucrose (IVIS) Therapy in Managing Anaemia among Pregnant Women in Primary Care Setting of Rural Haryana
Authors:   Research Scholar, Department of Community Medicine, Santosh Medical College and Hospital, Santosh Deemed to be University, Ghaziabad, Uttar Pradesh, India., Singh Abhishek
Published: October 2022

Background: Intravenous iron sucrose (IVIS) therapy is a newly introduced service component for combating moderate anaemia in pregnant women by the Haryana state as a public health measure from the year 2014. Aim: The aim of this study was to ascertain the effect of IVIS therapy on pregnant females having anaemia who were receiving this therapy in a primary care setting. Method: This prospective study was conducted at a randomly selected rural Primary Health Centre (PHC) in the Nuh district. 138 moderately anaemic females were given the standard form of IVIS therapy. The study subjects were requested to repeat haemoglobin levels after 2 weeks and 4 weeks of receipt of the last dose of therapy. Results: Of the total 154 anaemic pregnant women, 138 (89.6%) were diagnosed to have moderate anaemia. The number of study subjects with moderate anaemia reduced from 138 to 54, (54.54% reduction) when haemoglobin level was measured at the end of 4 weeks (endline). The mean rise in haemoglobin level among moderately anaemic pregnant females was 1.62 g/dL. At the end of 4 weeks (endline), 73.75% of the study subjects achieved normal levels of haemoglobin (from a total of 80 moderately anaemic women measurement). Conclusion: The mean rise in haemoglobin level in moderately anaemic pregnant females was 1.62 g/dL among participants who received IVIS therapy in a primary care setting in an underprivileged area in Haryana state. The women having severe anaemia achieved a better rise in Hb levels.
Preclinical Evaluation of Neuroprotective Activity of Piper nigrum L. in Cerebral Ischemic Reperfusion Induced Oxidative Stress
Authors:   Assistant Professor, School of Pharmacy, RK University, Rajkot, Gujarat, India, Raval Keval
Published: October 2022

Introduction: Stroke is a potentially fatal condition that is defined by the fast development of clinical symptoms of ischemia. Numerous flavonoids have been demonstrated in animal models to ameliorate brain ischemia-reperfusion damage. Piperine is a flavonoid derived from Piper nigrum L. that exhibits a variety of pharmacological effects. The purpose of this research was to determine if Piper nigrum L. has a protective effect against the brain damage caused by bilateral common carotid artery occlusion (BCCAO) in rats. Materials and Methods: The animal study was certified by Institutional Animal Ethics Committee (IAEC) under research project no. RKCP/COI/RP/12/28. Numerous parameters were evaluated to ascertain the extent of oxidative stress and eventual protection of Piper nigrumL. including glutathione (GSH), catalase (CAT), superoxide dismutase (SOD), lipid peroxidation (LPO), brain protein, and calcium levels in brain homogenate. The preventive effect of P. nigrum was evaluated and compared with quercetin as a standard using histopathology and the region of cerebral infarction. Results: In our research, we observed a substantial rise in superoxide dismutase (SOD), catalase, glutathione, and brain protein levels and a fall in lipid peroxidation and calcium levels in the P. nigrum and quercetin treated groups with the level of significance (p value) less than 0.05, confirming the protective effect against brain injury. Additionally, P. nigrum was shown to provide less protection compared to quercetin. Conclusion: As a result of these data, we hypothesise that P. nigrummay have a considerable neuroprotective effect in the brain against ischemic/ reperfusion-induced oxidative damage.
Blood Flow Restriction (BFR) Therapy to Rehabilitate Muscle Injuries in Post-operative Knee Patient
Authors:   Department of Physiotherapy, Chandigarh University, Chandigarh, India, Jatav Minakshi
Published: October 2022

KAATSU is a blood flow restriction training that was developed in Japan in the 1960s as a low-intensity strengthening exercise. It involves the wrapping of a tourniquet or pneumatic cuff over the muscle at a quick repetition rate during low-intensity muscle contractions. It is a muscle-strengthening technique used in physical therapy clinics to help patients regain muscle function following an injury or surgery. This is performed by temporarily cutting off blood flow to the muscles during the exercise. There were no linguistic or regional limitations in the literature searches for this article. This review contains a total of 25 records. Other resources were used to define additional elements. 4 records were duplicated and removed from the database. A total of 21 documents were found, with two being ruled out based on the title and abstract. Only 19 full-text items were authorised, and among these, 7 were eliminated because they were urgent research, case studies, and in a few studies, physical characteristics were not examined. This review article finally contained a total of 12 papers. Low-intensity exercise is used in blood flow restriction strengthening to achieve strength improvements similar to those seen in high-intensity training. BFR is a novel approach to physical therapy (PT). According to a preliminary study, this can result in adequate strength improvements during low-intensity exercise.
Correlation of Neurodegenerative Diseases with Oxidative Stress and Nutrition
Authors:   PhD (Foods and Nutrition), Department of Home Science, IIS (Deemed to be University), Jaipur, Rajasthan, India, Agarwal Vyoma
Published: October 2022

Technology or ease of doing work might be the greatest boon to this era, but it is still a bane for our health and life. Sitting in front of laptops or computers for several hours (sedentary lifestyle), using cell phones, watching television, skipping meals or eating junk/ fast food, lack of physical activities, stress, etc. increase the risk of many lifestyle diseases. All the above-mentioned habits increase the count of free radicals in our body and due to a lack of endogenous and exogenous antioxidants, the body cannot combat oxidative stress. Thus, the chances of occurrence of several chronic diseases like cancer, atherosclerosis, cardiovascular diseases, neurodegenerative diseases, rheumatoid arthritis, chronic inflammations, etc. increase. There are several factors contributing to neurodegeneration of the brain and neurons, in which oxidative stress plays an important role. This review article is the compilation of research done by several other researchers on Neurodegenerative Diseases (NDDs) and is primarily focused on better understanding a few basic questions like the correlation of oxidative stress and nutrition to neurodegeneration, NDDs, their different types, symptoms and causes followed by establishing a relation between oxidative stress and nutrition with the help of several studies carried out by researchers in this context.
Importance of Athlete Injury Management focusing on Evidence-based Approaches in Indian Physiotherapy Standards
Authors:   Faculty/ Senior Sports Physiotherapist, Department of Sports Medicine, Chettinad Academy of Research and Education, Chettinad Hospital and Research Institute, Chennai, Tamil Nadu, India, Thiyagarajan Alagappan
Published: October 2022

Injuries are common among athletes at any point in their sports carrier. Physiotherapy management plays a vital role in the rehabilitation of athlete injury. Numerous pieces of evidence suggest that quick fix approaches, lack of clinical reasoning skills in injury healing science, and current Indian medical system practising guidelines are the reason for poor quality treatment in India, and it is difficult to provide the best quality treatment as per the athletes’ requirements. A multidisciplinary team along with prompt evidence-based treatment is important in injury management. This article describes the current scenario in Indian physiotherapy as well as the suggestions and recommendations to implement evidence-based strategies for proper injury management among athletes.
Working capital management efficiency: a study of certified firms from the EFQM excellence model
Authors: Yousaf Muhammad
Published: October 2022

Working capital management (WCM) plays an important role in a firm’s value, financial risk, and firm profitability. WCM requires continuous management to maintain a certain level of the numerous components of working capital (WC). The main aim of this study is to estimate the efficiency of WCM of certified firms from the European Foundation for Quality Management (EFQM) Excellence Model. The study also tests the speed to attain each firm’s target level of efficiency using industry norms as the target level of efficiency. The financial data of the Czech certified firms from the manufacturing sector was derived from the CRIBIS database from 2015 to 2020. The efficiency of WCM is measured by utilization index (UI), performance index (PI), and efficiency index (EI). The findings revealed that Gerresheimer Horsovsky Tyn Spol., Miele Technika, and Koyo Bearings Česká Republika efficiently managed WC, as their indexes are greater than 1. The number of efficient firms was the lowest in 2020 based on the year-wise comparison which means that the efficiency of WCM of the firms was severely affected by the coronavirus pandemic (COVID-19). All the β values are lower than one, which signifies that none of the selected firms outperform the manufacturing industry as a whole. The findings of the current research are useful to the management of the firms and recommends that they give importance to the different indexes of WCM and efficiently use the current assets to generate sales.
Reliability of haemophilia early arthropathy detection with ultrasound (HEAD-US) in children: a comparative magnetic resonance imaging (MRI) study
Authors: Plut Domen , Kotnik Barbara Faganel , Pusnik Luka , Slak Peter , Snoj Ziga , Salapura Vladka
Published: October 2022

Background

Ultrasound (US) has been proven to be reliable in the assessment of early haemophilic arthropathy in the adult haemophilic population, however few studies so far focused on the reliability of US specifically in the paediatric haemophilic population. We were interested if the changing appearance of the growing bone hinders the ultrasonographic evaluation of the pathologic processes caused by haemophilic arthropathy. The aim of the study was to assess the reliability of US for evaluation of haemophilic arthropathy in children in comparison to magnetic resonance imaging (MRI).

Patients and methods

The study included all children aged 6 years or more with severe haemophilia in the country (n = 10). We assessed their elbows, knees, and ankles bilaterally by US and compared the results to the MRI as the reference standard. Pearson correlation coefficient (r) was used to analyse correlation.

Results

The correlation with MRI for the US for the total score was excellent for all joints (r = 0.849 for the elbows, r = 1 for knees, r = 0.842 for ankles). The correlation of scores for specific joint components showed fair, moderate, or excellent correlation for all joint components in all joints. The correlation was the lowest for the evaluation of cartilage and bone in the ankles (r = 0.546 and r = 0.478) and bone in the elbows (r = 0.499).

Conclusions

Our study proved that US using the HEAD-US method performed by paediatric radiologists is a reliable tool for detection and quantification of haemophilic arthropathy in children in comparison to MRI.
UNIVERSITY – VECTOR OF GLOBAL DEVELOPMENT
Authors:   Bucharest University of Economic Studies, Romania, ISTUDOR Nicolae , GOGU Emilia ,   Bucharest University of Economic Studies, Romania, PETRESCU Irina-Elena ,   Bucharest University of Economic Studies, Romania
Published: October 2022

The economic higher education system must be viewed as a competitive market where different players meet, interacting, each with a desire to achieve an efficient result - a successful and performant graduate. In this sense, the higher economic school must be approached as one of the main engines of society in sustainable development, in increasing the standard of living and the quality of life, respectively of human well-being. In this sense, the economic school must be continuously supported, developed and adapted.
SUPPORTING A HEALTHY ENVIRONMENT THROUGH LIVESTOCK
Authors:   Bucharest University of Economic Studies, Romania, BRAN Mariana , PĂTĂRLĂGEANU Simona Roxana ,   Bucharest University of Economic Studies, Romania, DINU Mihai ,   Bucharest University of Economic Studies, Romania, BEIA Silviu Ionut ,   University of Agronomic and Veterinary Medicine of Bucharest, Romania
Published: October 2022

The importance of animal husbandry reaches all aspects (social, economic and environmental) of sustainable development in rural areas. People produce for sale, but also for consumption. At the same time, considering the location of this economic activity and the practice of farm technology, it is necessary to observe certain norms in order to ensure good environmental conditions. Of course, the future points to the mistakes of the past. Today, modern animal technology is coordinated through IT programs, which anticipate not only the production but also the risks. Specialized literature indicates the environmental risks arising from cattle breeding at planetary level: accumulation of methane as a specificity of digestion, but also through accumulated manure. In this sense, however, the bibliographic studies and the statistical analyses are in favour of maintaining the herds of cattle, on condition there is genetic improvement in the nutritional aspect, as well as judicious waste management. These considerations are appreciated by Romanian farmers in the economic activity of cattle breeding, promoting measures to reduce greenhouse gases in this field.
IMPACT OF TAXATION ON AGRICULTURAL REVENUE OF FARMERS
Authors:   Institute of Agricultural Economics, Romanian Academy, IZVORANU Anca-Marina
Published: October 2022

Taxation is involved in all areas of life, economic, social and cultural. These sides are permanently correlated, interconnecting each other, inducing specific behaviors, each at the level of the other. The importance of the studied theme lies in this interdependence of the areas of control. The fiscal measures do not determine strictly economic characteristics, but they produce more or less profound social and cultural changes. Human actions, in general, take place with a certain direction, duration and intensity. The direction is established, most of the times, according to the objectives pursued, and the other two instruments, the duration and the intensity are relatively clear. The same aspects are also within the framework of taxation, the objectives are intensively pursued and are foreseen with certain periods of time. These, the objectives, are different from one period to another, changing both in intensity and duration. This is why it is very important to know what their effects are on the economic and social field, because they are created by the public power in order to positively affect both subjects, the state budget and the taxpayers.
TRADITIONAL FOODS AS A DRIVER FOR RURAL DEVELOPMENT THROUGH LOCAL RESOURCES UTILISATION
Authors:   Bucharest University of Economic Studies, Romania, TODIRICA Ioana
Published: October 2022

Nowadays there is much emphasis on rural development and reducing the gap between rural and urban areas. The disharmonious development is more and more visible in Romania as the years pass by. The present paper aims to present the importance of small producers and to provide a solution that can lead to the development of rural areas through local resources utilization. This approach has more implications, as it can be seen also as a sustainable way of development. Research methodology consists in utilization of primary data collected by the author and secondary data extracted from national databases. The main outcome of the study underlines the positive impact, from an economic standpoint, that small producers have at local level and their role in maintaining food diversity. The results should be of interest for national and local stakeholders.
STUDY ON THE ROLE OF LAND LEASING IN INCREASING THE SIZE OF AGRICULTURAL HOLDINGS
Authors:   Bucharest University of Economic Studies, Romania, STANCU Alina Mădălina , ANTOHE Radu ,   Bucharest University of Economic Studies, Romania, SUVOROV Nicolae ,   Bucharest University of Economic Studies, Romania, VASILE (DRĂCEA Lăcrămioara Alina ,   Bucharest University of Economic Studies, Romania
Published: October 2022

In the past, the constitution of the private land ownership right was the main desideratum of the agrarian reforms of the last decades, while the present route aims to increase the size of the agricultural holdings by initiating the lease process regarded as a classic form of exploiters acting as a contractor for the Romanian agrarian relations. This objective necessity of restructuring the state units and of the performance of the agricultural activity resides in the wide range of activities on the land market that concentrates around the regime of the land property in order to correctly appreciate the transactions in the lease market. The present paper aims to analyze the role and importance of land leasing by studying the average size of the agricultural exploitation of the last decade, registered at the level of the development area South-Muntenia, especially in Calarasi county. The result of the present research serves to demonstrate the role of the lease, which the lack of agrarian policy cannot prove its effectiveness having a non-stimulatory character for the owner.
CLIMATE CHANGE THREAT: WHERE ARE WE HEADING?
Authors:   Bucharest University of Economic Studies, Romania, ROTARU Ciprian , DUMITRACHE Victor-Marian ,   Bucharest University of Economic Studies, Romania
Published: October 2022

Our century is facing a major challenge, with implications that can endanger the existence of humanity - climate change. If hundreds of years ago, these climate changes were perceived as a reaction of nature, now, almost 300 years after the industrial revolution, part of humanity's activities in the struggle for survival are those that generate climate change. The challenges of climate change have become so complex that they require research and understanding of the phenomena in order to have an effective approach and implement the appropriate measures needed to mitigate the negative effects of the consequences of climate change. Agricultural is the one that generates climate change through GHG emissions, but at the same time is the sector most affected by these changes.
SOCIAL INNOVATION – SUSTAINABLE SOLUTION TO TACKLE ENERGY POVERTY IN URBAN AREA
Authors:   Bucharest University of Economic Studies, Romania, MUNTEANU Răzvan Aurelian
Published: October 2022

Innovation is about “new ideas” and social innovation is any activity, law, software, internal procedure, which is implemented for bringing added value into specific area and without those actions, couldn’t be possible to have better outcomes. A decision which is taken by the local authorities and it is improving the welfare it is also a social innovation. Often there is a confusion between “doing my job” and “social innovation”. In public administration there is a real need for social innovation, any good project could be a real social innovation if it brings added value. The paper presents a pilot project, with a target of 35-50 private houses selected in order to create a heterogeneous project with different type of buildings, from different geographic areas from District 1, from different years of construction, with a low level of income for each building, under 1000 euro/units. This last criterion has the roll to sustain and to tackle energy poverty. In terms of novelty, this represents a new approach in Romania, through the project we intend to test and to develop the sustainable and efficient technical solutions.
SUPPORTING THE DEVELOPMENT OF THE AGRICULTURAL SECTOR. CONSIDERATIONS REGARDING IMPROVING THE ECOLOGICAL AND ENVIRONMENTAL PERFORMANCE OF AGRICULTURE
Authors:   Bucharest University of Economic Studies, Romania, POPESCU Lavinia , SAFTA Adela Sorinela ,   Bucharest University of Economic Studies, Romania
Published: October 2022

The paper focused on reconsidering the role of applying strategies in soil treatment in agricultural production. Particular emphasis is placed on the interdependence between fertilizers applied to permanent pastures and agricultural plantations to improve soil quality. The main result of the research is to identify the correct management of nitrates in improving soil quality, as a means of sequestration of C at ground level by collecting data on nitrate efficiency and, consequently, carbon sequestration will contribute to the overall goal of significantly increasing carbon sequestration in the ground. During the research we tried to highlight aspects that, in our opinion, are important for the development of the agricultural sector, improving agricultural management by applying good practices responsible for the environment in terms of improving soil quality and preserving the biosphere and ecosystem.
Opportunities and Limitations of Turkey as a Mediator in Russian-Ukrainian Negotiations
Authors: Rustamova L. R.
Published: October 2022

Introduction. State mediation remains a requested activity in practical politics and an actual topic in the research field, as the number of conflicts has increased dramatically in the last decade, as well as long-standing frozen conflicts, which are poorly managed by intergovernmental organizations have escalated. At the same time, mediation and its principles are in the process of evolution, as more often large regional players become mediators, which themselves are active parties to conflicts. Under the change, in particular, was the principle of neutrality. This article focuses on the analysis of Turkey's mediation initiatives in the Russian-Ukrainian conflict and how it uses mediation to achieve its foreign policy goals. The article analyzes the goals of Turkish mediation, its ability to advance the negotiation process between the parties and the limitations that affect Turkey's position as a mediator.

Materials and methods. Russian and foreign studies on the effectiveness factors of states' mediation as a form of resolving international military conflicts were used as materials for writing the article. The methodological base was made up of discourse analysis and case studies. Turkey’s mediation in the Russian-Ukrainian conflict after the start of the Russian special operation in February 2022 was taken as a case.

Research results. At this stage, Turkey managed to organize several rounds of negotiations between Russia and Ukraine, which ended with the signing of important agreements on resolving some of the issues on the negotiation agenda, which are more related to the broad international consequences of the conflict than the main points of the negotiations demand of Russia and Ukraine. Nevertheless, the negotiations organized by Turkey in July 2022 allowed it to establish itself as a party that has a certain authority and weight among the negotiating parties. Turkey's resources of influence as a mediator include, in particular, extensive trade and economic ties and relations of interdependence and partnership with each of the parties to the conflict.

Discussion and conclusion. Since the negotiation process is in the dynamics of development, it is too early to conclude that Turkey has realized all the possibilities of mediation to resolve the conflict. However, its mediation has concrete results: its authority and geopolitical resources have made it possible to remove some of the problems that arose as a result of the Ukrainian conflict and have far-reaching consequences for international security. This allows us to conclude that Turkey has every opportunity to continue its mediation efforts to involve the parties in discussing the items on the negotiation agenda relating to the most pressing problems and which have become the direct cause of the clash. Therefore, the geopolitical consequences of Turkey's international activity in resolving the conflict in Ukraine will remain a hot topic for further study.
A New Schism: Church Diplomacy and the Ukrainian Crisis
Authors: Arteev S. P. , Sigachev M. I.
Published: October 2022

Introduction. This article analyzes the behavior of religious actors during the Russian Federation's special military operation in Ukraine. Ecclesiastical (church) diplomacy has gained a lot of attention from the media because of its attempts to resolve the situation. The Ukrainian crisis demonstrates that the relationship between religious actors and states is evolving from a secular model to a post-secular model, the general outline of which, however, has not yet been clearly formed. One way or another, the religious factor has become one of the key factors in the formula for analyzing and solving the Ukrainian crisis.

Materials and methods. The theoretical and methodological basis of the study, in addition to general scientific methods, were special political science research tools - actor and institutional approaches, comparative method, case study method.

Results of the research. The study revealed the key importance of Christian religious organizations, which more than others seek to participate in the resolution of the Ukrainian crisis and offer a variety of measures. At the same time, there is a commonality of positions between the official authorities of most states and the higher church hierarchs, based on their location. Such political interdependance of church and secular authorities has mixed consequences. Religious actors everywhere reduce the potential of their international political subjectivity. This is particularly noticeable in the case of the Russian Orthodox Church, which is substantially strengthening its position inside Russia but is becoming less influential outside it.

Discussions and conclusions. We argue that the world political system will continue to drift away from the ideals of the Modernity and its secular principle. At the same time it is hardly possible to talk about archaization in the form of desecularization. Rather the Ukrainian crisis promotes a post-secular model, a new balance between religion, state power and society. Meanwhile, the confrontational nature of interaction between Christian churches during the Russian special military operation in Ukraine further weakens the ecumenical movement and generates new schisms between Orthodox churches. This also affects the identitarian profile of the societies of the Euro-Atlantic and Eastern European states, which is becoming more flattened.
Due Performance of Contractual Obligations in the Context of Amendments to the Civil Code of the Russian Federation
Authors: Alyakin D. S.
Published: October 2022

Introduction. The paper examines the structure of due performance of obligations, as well as analyses the principal amendments to the civil law regulation of the relevant relations.

Materials and methods. The research material consisted of the Civil Code of the Russian Federation, jurisprudence, and scientific studies in the field of civil law. The methodological basis was composed of general scientific (analysis, synthesis, and analogy) and special legal methods (comparative-legal, formallogical, systemic, structural-functional methods, and method of interpretation).

Research results. The author notes that the amendments to the Civil Code of the Russian Federation and their construction by the Plenum of the Supreme Court of the Russian Federation, despite their focus on ensuring the due performance of obligations and increasing the protection level of rights and legitimate interests of parties, have both advantages and disadvantages that require further study and revision. These amendments are considered in the context of the specific performance of an obligation in relation to the due subject, persons, method, date, venue.

Сonclusion. The provisions on legal interest, differentiation between debt and payment currencies, alternative and optional obligations, additional requirements for performing an obligation to a due person, conditional performance of an obligation, possibility to set a date for performing an obligation which is linked to certain actions being performed by a party to a contract or concrete circumstances, date and venue of the performance of an obligation, which were included in the legislation, are well formulated. At the same time, it seems that the legal rules on the transfer of a creditor’s rights to a third party who performed the obligation instead of a debtor, performance of an obligation by a third party, partial performance of an obligation, early performance of an obligation require adjustments.
VARIABILIDAD GENÉTICA DE POBLACIONES NATURALES DE CASTAÑA Bertholletia excelsa EN LA REGIÓN DE MADRE DE DIOS, AMAZONIA PERUANA
Authors: PANDURO Hugo , CORVERA-GOMRINGER Ronald , CASTRO-RUIZ Diana , RENNO Jean-François , CASTILLO-TORRES Dennis del , GARCÍA Mildred , CUSI Edgar , RÍOS-ZUMAETA ‪Richer , ANGULO Carlos , ALVARADO Jhon , GARCIA-DAVILA Carmen
Published: October 2022

Fue determinada la variabilidad genética poblacional de la castaña Bertholletia excelsa en la región de Madre de Dios, mediante el análisis de 11 marcadores microsatélites en un total de 108 árboles. Los resultados globales mostraron una gran diversidad alélica (89 alelos, con una media de 8.09 alelos por locus), a nivel poblacional la mayor riqueza alélica fue encontrada en Iberia (AR = 4.82) y la menor en Itahuania (AR = 3.64), estas mismas localidades fueron las únicas que presentaron exceso de heterocigotos. Los resultados del análisis factorial de correspondencia (AFC) muestra una fuerte sobreposición genética entre la mayoría de las localidades analizadas. Los resultados del índice de Fijación (Fst) muestra que las localidades de Iñapari y Iberia están más relacionadas entre sí (Fst = 0.048), pero ligeramente diferenciadas con las demás localidades (los valores de Fst con las demás poblaciones variaron entre -0.001 a 0.193). El dendrograma basado en la distancia genética de Nei (1978) muestra que las 11 localidades se encuentran conformando tres agrupaciones genéticas diferentes, (A): Amigos, Pukiri, Itahuania y Manuripe; (B): Heath, Tambopata, Virgen del Carmen, Pariamanu, Iberia e Iñapari; y (C) conformada solo por la localidad de Alerta. Las agrupaciones dentro de los clusters podrían ser atribuidos a las escasas barreras físicas entre las localidades dentro de cada cluster, en tanto que las diferenciaciones entre los clusters podrían estar relacionado a la presencia de ríos entre estas agrupaciones, los cuales podrían constituir barreras físicas infranqueables para el flujo de genes entre estas agrupaciones.
OPTIMALISASI SISTEM PENYEDIAAN AIR MINUM PEDESAAN (SPAMDES) DI DUSUN KETUG KABUPATEN KARANGASEM
Authors: Werdi Ni Made Krisna , Suryantara I Putu Gustave , Parami Dewi Anak Agung Diah
Published: October 2022

SPAM (Sistem Penyediaan Air Minum) di Dusun Ketug Desa Antiga, Kecamatan Manggis,Kabupaten Karangasem mengalami kendala dalam pelaksanaannya, sehingga perlu dilakukan upayaoptimalisasi sebagai solusi dari permasalahan ini. Upaya optimalisasi ini dengan merencanakan beberapaopsi yang akan dihitung kelayakan finansialnya dan dianalisis dengan metode SWOT, sehingga mampumemberikan pilihan yang paling memungkinkan atau paling layak jika akan direalisasikan di DusunKetug. Dari hasil analisis yang telah dilakukan, maka didapatkan beberapa kesimpulan yaitu yangmenjadi kendala jaringan SPAMDES di Dusun Ketug Desa Antiga ialah tidak semua pelangganSPAMDES Dusun Ketug mendapat akses air, overflow pada bangunan reservoir SPAMDES DusunKetug, banyaknya air yang terbuang dikarenakan kebocoran pipa, dan setelah dilakukan analisis jaringandengan software Epanet didapatkan hasil bahwa dimensi pipa yang terpasang juga mempengaruhi aliranair. Kelayakan finansial SPAMDES di Dusun Ketug Desa Antiga dengan menganalisis 3 alternatif.Setelah dilakukan analisis kelayakan finansial maka didapatkan hasil ketiga alternatif Layak. Hasilkelayakan finansial ialah NPV = Rp59.000, BCR= 1,24, dan IRR= 12,27 % sehingga perencanaan inilayak. Hasil Analisis SWOT ketiga alernatif terpilih dengan memperhitungkan kekuatan, kelemahan,peluang, dan ancaman dari masing-masing alternatif tersebut. Sehingga mendapatkan hasil yangdianggap paling optimal ialah alternatif 28.
POTENSI RISIKO WAKTU PELAKSANAAN PROYEK SWAKELOLA DI KABUPATEN PASURUAN MELALUI PROGRAM KOTAKU KEMENTERIAN PUPR
Authors: Cahyono Luqman , Apriani Mirna , Nugraha Anggara Trisna , Prasetyo Utomo Agung
Published: October 2022

Pelaksanaan proyek swakelola dilakukan sepenuhnya oleh masyarakat mulai dari kegiatan perencanaan, pelaksanaan dan pengawasan. Masyarakat pengelola proyek mempunyai latar belakang pendidikan maupun pekerjaan yang kurang sesuai dengan bidangnya. Berbeda dengan kontraktual yang dikerjakan pihak ketiga yakni kontraktor atau konsultan yang memang sesuai bidangnya. Tujuan penelitian adalah untuk mengidentifikasi dan menganalisis risiko waktu dalam melaksanakan proyek swakelola masyarakat. Metode analisis data yang digunakan adalah studi pustaka, observasi, analisis mean, analisis risiko dan penyusunan matriks risiko. Hasil analisis menunjukkan terdapat 20 variabel risiko dengan rangking tertinggi produktivitas tenaga kerja rendah dimana skala pengukuran kemungkinan terjadi >60–80% dan dampak risiko terhadap waktu >7-30 hari dari durasi kerja. proyek, maka keputusan respons risiko "Avoidance" risiko harus dihindari.
Auricular Electroacupuncture in the Treatment of Gestational Diabetes: A Case Report
Authors:   Acuenergie Clinic, Peng Xiangping
Published: October 2022

This case shows that auricular Electroacupuncture (AE) not only effectively reduces blood sugar levels, but it also significantly improves the subjective symptoms, helps patients to avoid taking medication, and prevents the progression of gestational diabetes
Applicability of Dermoscopy in the Atypical Presentation of Tinea Pedis: A Case Report
Authors:   Nijalingappa Medical College, Navanagar, Ankad Balachandra S
Published: October 2022

Tinea pedis, also known as athlete’s foot or foot ringworm is an infection of the feet or toes with dermatophyte fungus [1]. Trichophyton rubrum is the most common isolate accounting for 70% of cases. Other species include Trichophyton interdigitale, Trichophyton mentagrophytes and Epidermophyton floccosum. The ideal conditions for fungal growth include hot and humid environment, prolonged use of occlusive footwear, excessive sweating and prolonged exposure to water [2]. The maceration of the skin due to above risk factors along with keratinases released by fungus helps in easy invasion of the keratin layer. The mannans contained in the fungal cell wall also further suppress the body’s immunity thus, contributing to tinea pedis. Herein we describe a case of recurrent vesiculobullous type of tinea pedis who was inappropriately managed previously.
Factors Associated with Severe and Active Thyroid-Eye Disease in a Tertiary Hospital Setting
Authors:   Factors Associated with Severe and Active Thyroid-Eye Disease in a Tertiary Hospital Setting, Medalle Ronald Steven
Published: October 2022

Risk factors and disease characteristics of TED cases at EAMC coincide with local published journals, except for significant correlation with male sex and TRAb titers showing the variability of the disease and the need for further studies.
One-Year Postoperative Outcomes following Transfixion of Foldable Intraocular Lens with Polytetrafluoroethylene Suture for Scleral Fixation
Authors:   Centro Oftalmologico De Valencia CEOVAL, Av. Bolivar Norte, Edificio Torre Venezuela, Piso 2., Valencia, Venezuela, Pineda-Fernandez Angel ,   Servicio De Oftalmologia “Dr. Jose Manuel Vargas Ochoa” De La Ciudad Hospitalaria Dr. Enrique Tejera, Universidad De Carabobo, Valencia, Venezuela, Chen Yan ,   Centro Oftalmologico De Valencia CEOVAL, Av. Bolivar Norte, Edificio Torre Venezuela, Piso 2., Valencia, Venezuela,   Oftalmosaud, Lima, Peru, Rodriguez Leonidas ,   Servicio De Oftalmologia “Dr. Jose Manuel Vargas Ochoa” De La Ciudad Hospitalaria Dr. Enrique Tejera, Universidad De Carabobo, Valencia, Venezuela
Published: October 2022

We examined 19 eyes of 19 patients. Significant improvement in visual acuity was noted in all cases. In addition, most of the IOLs (84.21%) were well centered, and 3 eyes (15.78%) presented mild inferior decentration. Only one eye (5.26%) developed mild pigment dispersion with no evidence of glaucoma.
Pineal Gland Mass presenting as Parinaud Syndrome in a 21 Year Old Patient
Authors:   Department Of Ophthalmology, Rizal Medical Center, Pasig Boulevard, Pasig City, Philippines, Lim1 Patricia Abigail , Ang Lourdes ,   Department Of Ophthalmology, Rizal Medical Center, Pasig Boulevard, Pasig City, Philippines
Published: October 2022

We report a case of a 21-year-old Filipino, with a history of progressive diplopia, who presented with headache, dizziness and vomiting. Ophthalmologic exam revealed light near dissociation, physiologic anisocoria, bilateral upgaze palsy, convergence retraction nystagmus and pseudo-abducens palsy of the left eye. Imaging was done, which revealed pineal neoplasm with obstructive hydrocephalus. This text aims to present a case of pineal gland neoplasm which presented as diplopia alongside signs and symptoms of Dorsal Midbrain Syndrome (Parinaud Syndrome).
Stem Cells Administration in Cystic Kidney Animal Models: New Potential Therapeutic Approach
Authors:   Medical Research Center, Medical Faculty Mannheim, University Of Heidelberg, Theodor-Kutzer-Ufer, Mannheim, Germany, Nardozi Daniela , Gretz Norbert ,   Medical Research Center, Medical Faculty Mannheim, University Of Heidelberg, Theodor-Kutzer-Ufer, Mannheim, Germany
Published: October 2022

ystic Kidney Disease (CKD) represents a heterogeneous group of chronic disorders and the fourth leading cause of end stage renal disease. CKD incidence has been increasing every year for several decades
Optimized Decellularization Methods of the Heart in Tissue Engineering
Authors:   Department Of Cell Biology, King Faisal Specialist Hospital And Research Center, Saudi Arabia, Al-Hijailan Reem Saud
Published: October 2022

Despite remarkable advance in tissue, cells and organ transplantation in the past decades, hurdles such as biocompatibility, biofunctionality and organ donor availability still exist. Therefore, a new paradigm alternatively emerged to reconstruction of tissues termed “Tissue Engineering”
Misión, Visión y Apropiación de Valor: Un Análisis de Correlaciones
Authors: Contreras-Pacheco Orlando E. , Pirazán Parra Alejandra , Villarreal Pinzón Maira
Published: October 2022

El presente estudio se centra en la discusión sobre la utilidad efectiva de las declaraciones de misión y visión en un ámbito empresarial. Para ello, se evalúa la asociación existente entre estos dos elementos de naturaleza estratégica con respecto a la consecución de resultados, especialmente en términos de la capacidad competitiva de una compañía. Puntualmente, se formula un planteamiento conceptual conducente a determinar la potencial incidencia de una misión y una visión de calidad sobre los niveles organizacionales de apropiación de valor. Posteriormente, haciendo uso de un modelamiento de ecuaciones estructurales mediante mínimos cuadrados parciales, dicho planteamiento es evaluado sobre una muestra de 120 grandes compañías registradas en el Departamento de Santander, Colombia. Los hallazgos sugieren que, pese a que existe una asociación positiva entre una misión y una visión de calidad, la apropiación de valor solo parecería depender de lo primero y no de lo segundo. El estudio valida la idea de que una misión adecuadamente construida podría llegar a ser una herramienta poderosa en términos no solo de formulación, sino de la implementación de estrategias. Adicionalmente, declara que la capacidad de construcción de una misión de calidad está relacionada con la capacidad que tiene la compañía de crear y apropiar valor y, por ende, ser competitiva.
Elaboración de néctares de pera, durazno y manzana utilizando como agente conservante extractos acuosos obtenidos de canela (Cinnamomum verum).
Authors: Milian Mindola Pablo Ernesto
Published: October 2022

El presente estudio plantea la aplicabilidad de extractos naturales y su inclusión en la formulación de bebidas de néctares elaboradas con pulpas de pera, durazno y manzana con la finalidad de evaluar la interacción de diferentes variables de tipofisicoquímicas, microbiológicas, sensoriales y, finalmente, el impacto que ejerce sobre la conservación y la vida útil de este tipo de productos. Se obtuvieron extractos acuosos a partir de astillas de canela (Cinnamomum verum), a través del método decalentamiento, separación de fases y filtración. Se realizaron filtrados sucesivos en sistema de vacío, hasta obtener los extractos los cuales fueron almacenados en frascos de vidrio estériles color ámbar a 4 ºC. Se evaluó el efecto de la inclusión de losextractos acuosos de canela en la formulación de néctares de pera, manzana y durazno, en paralelo con tratamientos adicionados con un conservante convencional de origen químico (sorbato de potasio) y un tratamiento control sin ningún tipo deconservante a los cuales no se les aplicó tratamiento térmico de pasteurización. Se evaluaron características microbiológicas (mesófilos aerobios, mohos y levaduras) y fisicoquímicas (acidez titulable, grados Brix – sólidos solubles, pH y densidad) el día0 correspondiente al día de producción y, posteriormente, con intervalos de cinco días para cada una de las frutas evaluadas. Se evidenció que las variables microbiológicas de mesófilos aerobios, mohos y levaduras presentan un significativo aumento después del día 20 de producción solo en los tratamientos control sin la adición de ningún conservante para los néctares de manzana y pera y a partir del día 15 para el tratamiento control de los de durazno. La acidez titulable y pH, tuvieron un comportamiento muy estable en función de los días de producción evaluados, pero se encontraron diferencias significativas en los tratamientos con sorbato de potasio con respecto a los tratamientos control y extracto acuoso de canela, lo que indica unefecto positivo de estos sobre la estabilidad del pH en los néctares de las frutas en un rango de 3,25 a 3,60, como parámetro de conservación de la vida útil.
El estado del arte de la trazabilidad metrológica en la Medicina de Laboratorio
Authors: Quintana-Ponce Sandra
Published: October 2022

Equivalence of results issued by clinical laboratories can be achieved by standardization or harmonization. The generation of comparable results allows common reference intervals between laboratories using different measurement procedures and materials for calibration and trueness control. The aim of this article is to describe the state of the art of metrological traceability in laboratory medicine, currently highlighted through the guidelines of ISO 17511, which in its 2020 version, shows six different hierarchical alternatives, ranging from comparability to certified reference materials and reference measurement procedures, to traceability only to the manufacturer. This new version of 17511 adds the possibility to demonstrate traceability to international harmonization protocols. Demonstrating metrological traceability is required to achieve ISO 15189 accreditation for clinical laboratories. To achieve equivalence of measurements in laboratory medicine, it is desirable to bring clinical laboratory professionals closer to the metrological language and the stakeholders involved.
The Effect of Content Feeding on Electronic Word of Mouth (E-WOM)Activities Mediatedby Information Dissemination
Authors: Wahab Zakaria , Fitrianto Eko Mohammad , Hanafi Agustina
Published: October 2022

This research was conducted to examine the mediating role of information dissemination (seeding) in the relation between marketing campaigns (content feeding) and electronic word of mouth (eWOM). The research object is three marketing campaigns from three online marketplaces in Indonesia, named: Shopee, Tokopedia, and Bukalapak. A model was built to test and evaluate and test the mediation effect existence. The number of participants was involved in this research is 200 participants, and they answer the specific question related to the research. We found that all regression path in the models is significant, that indicate direct and indirect effect happened simultaneously. Our conclusion is information dissemination (seeding activity) playing an important role as a partial mediating variable. Other implications and future research discussed.
Keywords — E-WoM, Marketing Campaign, Content Feeding, Content Seeding
The Development and Validation of Financial Management Behavior (FMB) Scale in Postgraduate Students
Authors: Amri Andi , Ramdani Zulmi , Warsihna Jaka , Tae Lidwina Felisima
Published: October 2022

This study aims to develop and validate a financial management behavior scale. This study used the approach of measuring instrument modification by applying the existing theory into a statement that will be used as an instrument to see the condition of a person's financial management behavior. The researchers used the basic theory of Dew and Xiao (2011) which divides financial management behavior into the consumption dimension, cash flow management dimension, savings and investment dimension, and debt management dimension. The subjects involved in this study were 391 people who were postgraduate students in the capital city of Jakarta and were selected using a purposive sampling technique. Structural equation modeling (SEM) analysis with AMOS software were used in this study. The results of the analysis showed that the financial management behavior scale developed by the researchers has met the fit model and produced a valid statement which is ready to be used to measure the behavioral conditions of one's financial management specifically in the student context. The limitations and suggestions will be discussed further in this article.
Keywords— Financial Management; Financial Management Behaviour; Scale Development; Scale Validation
Human Resources Management in Family Businesses – Case of North Macedonia
Authors: Abduli Selajdin , Arifi Avni
Published: October 2022

This paper analyses one of the most important aspects of any organization, and that is how to manage human resources in a specific type of business, i.e., family businesses in North Macedonia. The reason for focusing on this topic is twofold. First, family businesses make up the majority of businesses in North Macedonia, and secondly, the HRM in these businesses is very specific and complex. The research was done through the questionnaire (distributed electronically and physically) by surveying family businesses in North Macedonia, in total 150 questionnaires were distributed and 141 were received. The questionnaire included 15 questions which included some general information about the family business profile, to continue with the part that deals with aspects of human resource management. The results obtained from the research provide an overview of how important human resources are considered for family businesses in North Macedonia and how managing them adequately affects the performance of businesses and employees.
Keywords— Human Resource Management, family businesses.