bluuebunny/crossref_metadata_2025 huggingface dataset:
Performance Analysis and Optimization of a Cooling System for Hybrid Solar Panels Based on Climatic Conditions of Islamabad, Pakistan
Authors: Sattar Mariyam , Rehman Abdul , Ahmad Naseem , Mohammad AlSharef , Al Ahmadi Ahmad Aziz , Ullah Nasim
Published: August 2022

The unconvertible portion of incident radiation on solar panels causes an increase in their temperature and a decrease in efficiency due to the negative temperature coefficient of the maximum power. This problem is dealt with through the use of cooling systems to lower the temperature of photovoltaic (PV) panels. However, the developments are focused on the loss of efficiency or extract the heat out of the solar panel, rather than optimizing the solution to produce a net gain in the electric power output. Therefore, this study proposes the analytical model for the cell temperature, irradiance and design of absorbers. Furthermore, the cooling systems for the hybrid solar panels were developed through analytical modeling of the solar cell temperature behavior and heat exchange between the fluid and back surface of the PV module in MATLAB. The design parameters such as mass flow rate, input power, solar cell temperature, velocity, height, number of passes and maximum power output were optimized through a multi-objective, multivariable optimization algorithm to produce a net gain in the electrical power. Three layouts of heat absorbers were considered—i.e., single-pass ducts, multi-pass ducts, and tube-type heat absorbers. Water was selected as a cooling medium in the three layouts. The optimized results were achieved for the multi-pass duct with 31 passes that delivered a maximum power output of 186.713 W at a mass flow rate of 0.14 kg/s. The maximum cell temperature achieved for this configuration was 38.810 °C at a velocity of 0.092 m/s. The results from the analytical modeling were validated through two-way fluid-solid interaction simulations using ANSYS fluent and thermal modules. Analyses revealed that the multi-pass heat absorber reduces the cell temperature with the least input power and lowest fluid mass flow rate to produce the highest power output in the hybrid PV system.
Competition and Facilitation Co-Regulate Spatial Patterns and Coexistence in a Coniferous and Broad-Leaved Mixed Forest Community in Zhejiang, China
Authors: Yao Liangjin , Wang Zhigao , Wu Chuping , Yuan Weigao , Zhu Jinru , Jiao Jiejie , Jiang Bo
Published: August 2022

Plant interactions have long been the subject of intense research and debate in ecology. Competition and facilitation are known to be the basic drivers of community structure, species coexistence, and forest succession dynamics; however, there remains a lack of understanding of how spatial patterns affect these in the mixed forest community of coniferous and broad-leaved species. In the present study, we studied the roles of competition and facilitation in a mixed forest community in the Zhejiang Province, China. For this, we divided plants measured at a study site according to the size of the diameter at breast height (DBH) into three levels of saplings as follows: saplings (1 cm ≤ DBH < 5 cm), juveniles (5 cm ≤ DBH < 15 cm), and adults (DBH ≥ 15 cm). We used the spatial point pattern method to explore the raw number, spatial distribution, and both intra- and inter-specific correlations of coniferous and broad-leaved species at these different diameter levels. The corresponding findings were as follows. First, the DBH and structure of coniferous and broad-leaved species were similar, showing a distinct distribution in an inverted “J” shape as the number of individuals with a particular diameter declined as DBH increased. Second, when all individuals of a similar diameter range were pooled, coniferous species were clustered at all size scales; however, in this situation, broad-leaved species (evergreen and deciduous) showed a clumped distribution at small scales, and this decreased as spatial scale increased. Third, there were small, but significant positive correlations between large-diameter trees and small-diameter trees of coniferous species and between evergreen broad-leaved species at different diameter levels; however, as the scale increased, the correlation diminished. On any scale, individual deciduous broad-leaved species at different diameter ranges did not have any significant correlation. Fourth, coniferous species had a strong competitive effect on broad-leaved species, and there was a weak promoting effect between deciduous and evergreen broad-leaved species as well. In summary, different tree species occupy similar living spaces, and through competition and facilitation, regulate the spatial pattern and community stability of coniferous and broad-leaved species in mixed forest communities.
Habitat Conditions and Tree Species Shape Liana Distribution in a Subtropical Forest
Authors: Li Buhang , Zhang Yingming , Luan Fuchen , Yuan Zuoqiang , Ali Arshad , Chu Chengjin , Bin Yue
Published: August 2022

Lianas are woody plants that require external support to reach the canopy. They are expanding in forests worldwide, possibly due to climate change and forest disturbance. Most studies on lianas have been conducted in tropical forests. Lianas are less explored in subtropical forests. We aimed to document the density and diversity of lianas, to test how habitat condition and the distribution of tree species affect the distributions of lianas based on data from a fully mapped 20 ha plot in subtropical China. We analyzed habitat association by fitting a generalized linear model with family-level liana abundance as response variable and family identity, and its interaction terms with topographic variables (slope, convexity, elevation, and sin(aspect)), as explanatory variables. We focused on the spatial associations of three liana species and 82 tree species with ≥100 individuals using the pair correlation function and redundancy analysis. We found a total of 1305 lianas, falling into 26 species, and 16 families, in the 20 ha plot. They accounted for 1.5% of individuals, 11.7% of species, and 0.4% of total basal area of woody plants in the plot. There were large variations in distributions of liana with respect to the four topographic variables among families, contrasting with former findings suggesting that lianas favor dry and hot habitats. The three most abundant liana species showed non-random associations with tree species, and they tended to positively associate with similar tree species but negatively associate with different tree species. The distribution of tree species explained 21.8% of variance in liana distribution. Our study suggested that both habitat conditions and tree composition intervene in determining liana distributions and that habitat heterogeneity may be a mechanism for liana diversity maintenance. Our study provides a basic understanding of liana diversity and distribution in this subtropical forest and contributes to future planning of liana studies and diversity conservation in subtropical forests under climate change.
Growing of the Containerized Seedlings of English Oak (Quercus robur L.) to Establish Sustainable Plantations in Forest-Steppe Ukraine
Authors: Reho Mariana , Vilček Jozef , Torma Stanislav , Koco Štefan , Lisnyak Anatolij , Klamár Radoslav
Published: August 2022

The topical issues for elaboration of new approaches to grow English oak (Quercus robur L.) seedlings with the purpose to establish sustainable plantations in forest-steppe Ukraine. The goal of the research is to elaborate a technology for growing the containerized seedlings of English oak. Oaks are among the most common tree species found throughout the world. Throughout history, oaks have provided humans and wildlife with shelter, and food. However Ukrainian forests face multiple natural and anthropogenic pressures. Climate change generates a particular threat for Ukrainian forests and stability of agroforestry landscapes. This paper considers the impacts of expected climate change on vulnerability of Ukrainian forests, especially for oaks. In response to forest depletion, stricter forest management practices emerged to replant, protect and maintain forest cover and the multi-functionality of forests in terms of wood production. Even though oaks have wide ecological amplitudes of suitable growing conditions, Ukrainian forests dominated by oaks often fail to regenerate naturally. In this regard, it is necessary to increase the cultivation of crops in containers. Field germination of oak seedlings in containers with different substrate composition was identified in the case study in the conditions of Ukrainian Left-bank Forest-Steppe. The height and diameter values of the seedlings were investigated and summarized including the influence of the root ball substrate composition. We tested different compositions of the substrate containing low-land peat, which is rich in nutrients and mixtures with different ratios of soil, humus and sawdust. The advantage over the control in germination ability, survival and condition has been experimentally proved for variants with the use of peat in the substrate and, to a large extent, for the variant with the use of soil, humus and sawdust. Among tested substrates, the peat-containing variant with equal portions of dark gray wooded middle loamy soil and peat (peat:soil = 1:1) and the variant of the three-component mixture soil:humus:sawdust = 4:2:1 are the most balanced in the basic soil parameters (acidity and nutrient content). In the same time they are the best among the studied ones for the productive growing of English oak seedlings. The use of containerized planting stock allowed foresters not only to significantly extend the terms of forest planting, which is particularly topical for Ukraine, but also to increase the root-taking of planting stock up to nearly 100% in forest-cultivated areas.
Timber Tracking in a Mountain Forest Supply Chain: A Case Study to Analyze Functionality, Bottlenecks, Risks, and Costs
Authors: Pichler Gerhard , Sandak Jakub , Picchi Gianni , Kastner Maximilian , Graifenberg Diego , Stampfer Karl , Kühmaier Martin
Published: August 2022

Digital transformation of the timber supply chain is more relevant at present than ever before. Timber tracking is one example of digital transformation, and can be performed in various locations, from the forest to the mill, or even beyond, to the final timber product. The integration of new technologies in the forestry and timber industries should contribute to enhancing supply chain efficiency and safety. For this purpose, a new timber tracking and processing system was tested by integrating RFID (Radio Frequency IDentification) technology with digital survey tools and intelligent machines, into a smart timber supply chain. A case study on this process was carried out in a mountain forest in Austria. The tags were used to link information to single items (trees and logs) and transfer relevant data (species, diameter, length, volume, defects, density, stiffness, branchiness, etc.), throughout the whole supply chain. The performance of the technology was analyzed by means of process flow, bottleneck, and risk analyses. Fourteen spruce trees went through the supply chain process from the forest stand to the log yard, monitored by the new timber tracking and processing system. The results revealed that the new system is useful for transferring information through the timber supply chain, and the system costs remained at a normal market level. The weakest point in the supply chain was the processing of the trees by the intelligent prototype processor. A high error rate and low durability lead to higher idling time and harvesting cost, but the findings of this study can be used to further improve this system. All other processes worked well and were at a marketable level.
EHBP1L1 Frameshift Deletion in English Springer Spaniel Dogs with Dyserythropoietic Anemia and Myopathy Syndrome (DAMS) or Neonatal Losses
Authors: Østergård Jensen Sarah , Christen Matthias , Rondahl Veronica , Holland Christopher T. , Jagannathan Vidhya , Leeb Tosso , Giger Urs
Published: August 2022

Hereditary myopathies are well documented in dogs, whereas hereditary dyserythropoietic anemias are rarely seen. The aim of this study was to further characterize the clinical and clinicopathological features of and to identify the causative genetic variant for a dyserythropoietic anemia and myopathy syndrome (DAMS) in English springer spaniel dogs (ESSPs). Twenty-six ESSPs, including five dogs with DAMS and two puppies that died perinatally, were studied. Progressive weakness, muscle atrophy—particularly of the temporal and pelvic muscles—trismus, dysphagia, and regurgitation due to megaesophagus were observed at all ages. Affected dogs had a non-regenerative, microcytic hypochromic anemia with metarubricytosis, target cells, and acanthocytes. Marked erythroid hyperplasia and dyserythropoiesis with non-orderly maturation of erythrocytes and inappropriate microcytic metarubricytosis were present. Muscle biopsies showed centralized nuclei, central pallor, lipocyte infiltrates, and fibrosis, which was consistent with centronuclear myopathy. The genome sequencing of two affected dogs was compared to 782 genomes of different canine breeds. A homozygous frameshift single-base deletion in EHBP1L1 was identified; this gene was not previously associated with DAMS. Pedigree analysis confirmed that the affected ESSPs were related. Variant genotyping showed appropriate complete segregation in the family, which was consistent with an autosomal recessive mode of inheritance. This study expands the known genotype–phenotype correlation of EHBP1L1 and the list of potential causative genes in dyserythropoietic anemias and myopathies in humans. EHBP1L1 deficiency was previously reported as perinatally lethal in humans and knockout mice. Our findings enable the genetic testing of ESSP dogs for early diagnosis and disease prevention through targeted breeding strategies.
Ectopic Expression of the Rice Grain-Size-Affecting Gene GS5 in Maize Affects Kernel Size by Regulating Endosperm Starch Synthesis
Authors: Dong Guoqing , Xiong Hanxian , Zeng Wanyong , Li Jinhua , Du Dengxiang
Published: August 2022

Maize is one of the most important food crops, and maize kernel is one of the important components of maize yield. Studies have shown that the rice grain-size affecting gene GS5 increases the thousand-kernel weight by positively regulating the rice grain width and grain grouting rate. In this study, based on the GS5 transgenic maize obtained through transgenic technology with specific expression in the endosperm, molecular assays were performed on the transformed plants. Southern blotting results showed that the GS5 gene was integrated into the maize genome in a low copy number, and RT-PCR analysis showed that the exogenous GS5 gene was normally and highly expressed in maize. The agronomic traits of two successive generations showed that certain lines were significantly improved in yield-related traits, and the most significant changes were observed in the OE-34 line, where the kernel width increased significantly by 8.99% and 10.96%, the 100-kernel weight increased by 14.10% and 10.82%, and the ear weight increased by 13.96% and 15.71%, respectively; however, no significant differences were observed in the plant height, ear height, kernel length, kernel row number, or kernel number. In addition, the overexpression of the GS5 gene increased the grain grouting rate and affected starch synthesis in the rice grains. The kernels’ starch content in OE-25, OE-34, and OE-57 increased by 10.30%, 7.39%, and 6.39%, respectively. Scanning electron microscopy was performed to observe changes in the starch granule size, and the starch granule diameter of the transgenic line(s) was significantly reduced. RT-PCR was performed to detect the expression levels of related genes in starch synthesis, and the expression of these genes was generally upregulated. It was speculated that the exogenous GS5 gene changed the size of the starch granules by regulating the expression of related genes in the starch synthesis pathway, thus increasing the starch content. The trans-GS5 gene was able to be stably expressed in the hybrids with the genetic backgrounds of the four materials, with significant increases in the kernel width, 100-kernel weight, and ear weight. In this study, the maize kernel size was significantly increased through the endosperm-specific expression of the rice GS5 gene, and good material for the functional analysis of the GS5 gene was created, which was of great importance in theory and application.
The GDAP1 p.Glu222Lys Variant-Weak Pathogenic Effect, Cumulative Effect of Weak Sequence Variants, or Synergy of Both Factors?
Authors: Kabzińska Dagmara , Chabros Katarzyna , Kamińska Joanna , Kochański Andrzej
Published: August 2022

Charcot–Marie–Tooth disorders (CMT) represent a highly heterogeneous group of diseases of the peripheral nervous system in which more than 100 genes are involved. In some CMT patients, a few weak sequence variants toward other CMT genes are detected instead of one leading CMT mutation. Thus, the presence of a few variants in different CMT-associated genes raises the question concerning the pathogenic status of one of them. In this study, we aimed to analyze the pathogenic effect of c.664G>A, p.Glu222Lys variant in the GDAP1 gene, whose mutations are known to be causative for CMT type 4A (CMT4A). Due to low penetrance and a rare occurrence limited to five patients from two Polish families affected by the CMT phenotype, there is doubt as to whether we are dealing with real pathogenic mutation. Thus, we aimed to study the pathogenic effect of the c.664G>A, p.Glu222Lys variant in its natural environment, i.e., the neuronal SH-SY5Y cell line. Additionally, we have checked the pathogenic status of p.Glu222Lys in the broader context of the whole exome. We also have analyzed the impact of GDAP1 gene mutations on the morphology of the transfected cells. Despite the use of several tests to determine the pathogenicity of the p.Glu222Lys variant, we cannot point to one that would definitively solve the problem of pathogenicity.
Gas Permeability Behavior in Frozen Sand Controlled by Formation and Dissociation of Pore Gas Hydrates
Authors: Chuvilin Evgeny , Zhmaev Maksim , Grebenkin Sergey
Published: August 2022

Formation and dissociation of pore gas hydrates in permafrost can change its properties, including fluid flow capacity. Permeability is one of the most significant parameters in the study of hydrate-containing rocks, especially in the case of gas burial or extraction. Gas permeability variations in frozen sand partially saturated with CO2 or CH4 hydrates are studied experimentally at a constant negative temperature of −5 °C, as well as during freezing–thawing cycles. The gas permeability behavior is controlled by the formation and dissociation of pore gas hydrates in frozen sand samples. The samples with an initial ice saturation of 40 to 60% become at least half as permeable, as 40% of pore ice converts to hydrate. The dissociation process of accumulated hydrates was modeled by both depressurizing methane or CO2 to atmospheric pressure and by stepwise injection of gaseous nitrogen up to 3 MPa into a frozen sample. In sand samples, with a decrease in gas pressure and without subsequent injection of nitrogen, a decrease in pore hydrate dissociation due to self-preservation was noted, which is reflected by a deceleration of gas permeability. Nitrogen injection did not lead to a decrease in the rate of dissociation in the frozen hydrate-containing sample, respectively, as there was no decrease in the rate of gas permeability.
Risk Factors and Risk Stratification of Thromboembolic Risk in Patients with Multiple Myeloma
Authors: Chaireti Roza , Nahi Hareth
Published: August 2022

Multiple myeloma (MM) is a hematological malignancy characterized by a high risk for thrombotic episodes, mainly venous thromboembolism (VTE). This risk is accentuated by cancer treatments such as immunomodulatory drugs (IMiDs). Cancer-associated thrombosis is one of the leading causes of mortality and morbidity, and the prevention of thrombosis is, therefore, of paramount significance. To this day, it is unclear which type of thromboprophylaxis is the most effective. This is partly due to the multifactorial etiology behind thrombosis since the compound of patient-, disease- and treatment-associated factors characterizing each patient with MM is unique. Additionally, the established risk scores are not reliable in patients with MM. The scope of this review is to summarize the factors contributing to increased thrombosis risk in MM, as well as the risk scores and thromboprophylaxis regimes available.
The Analysis of Red Lead Endsheets in Rare Books from the Fung Ping Shan Library at the University of Hong Kong
Authors: Querner Pascal , Beenk Jody , Linke Robert
Published: August 2022

Stored under optimal conditions, paper can last for hundreds of years; however, paper is also susceptible to numerous agents of deterioration as it is primarily made of cellulose fibre derived from plant cell walls. Paper is especially vulnerable under conditions with high temperature and humidity, which together can encourage mould growth and foster insect pests. Pest infestation is a common type of deterioration responsible for significant damage to paper and books. Endsheets prepared with red lead and sewn into traditional Chinese bookbindings are a historical method used to minimise insect damage to books in southern China. Samples of red-coloured papers from the Fung Ping Shan Library at the University of Hong Kong were assessed. Two types of so called wan nian hong papers (萬年紅紙), (1) damaged and (2) undamaged by insects, were analysed with a scanning electron microscope equipped with an energy dispersive X-ray fluorescence detector. The chemical analyses reveal high concentrations of red lead (lead tetroxide, Pb3O4) in the undamaged papers, and only very few traces of lead in the damaged papers. The orange papers with insect feeding tunnels seem to have been only coloured in orange, and not treated with red lead as a biocide. These results are discussed and compared with modern treatment methods in the integrated pest management of books, archive, and library materials in (a) Europe and (b) Asia.
Perceptions of Antenatal Exercise in Pregnant Females and the Impact of COVID-19
Authors: France-Ratcliffe Madeleine , Hopkins Nicola D. , Low David A. , Cocks Matthew S. , Jones Helen , Sheen Kayleigh S. , Sprung Victoria S.
Published: August 2022

Exercise during pregnancy presents many benefits for the mother and baby. Yet, pregnancy is characterised by a decrease in exercise. Studies have reported barriers to antenatal exercise. The coronavirus (COVID-19) pandemic may have further exacerbated barriers to antenatal exercise as pregnant females faced many challenges. Rich, in-depth exploration into pregnant female’s perceived barriers to antenatal exercise during COVID-19 is imperative. Questionnaires reporting physical activity levels were completed by all participants (n = 14). Semi-structured interviews were conducted between November 2020 and May 2021 in the UK. Interviews were analysed using thematic analysis and revealed four main themes: ‘Perceptions of being an active person shaping activity levels in pregnancy’, ‘How do I know what is right? Uncertainty, seeking validation and feeling informed’, ‘Motivators to antenatal exercise’ and ‘A process of adaptations and adjustment’. Findings indicate that the COVID-19 pandemic exacerbated barriers to antenatal exercise and highlight the importance of direct psychosocial support and clear, trustworthy information. Findings also support the fundamental need for better education amongst healthcare professionals regarding antenatal exercise.
Moral Distress Scores of Nurses Working in Intensive Care Units for Adults Using Corley’s Scale: A Systematic Review
Authors: Giannetta Noemi , Villa Giulia , Bonetti Loris , Dionisi Sara , Pozza Andrea , Rolandi Stefano , Rosa Debora , Manara Duilio Fiorenzo
Published: August 2022

Background: No systematic review in the literature has analyzed the intensity and frequency of moral distress among ICU nurses. No study seems to have mapped the leading personal and professional characteristics associated with high levels of moral distress. This systematic review aimed to describe the intensity and frequency of moral distress experienced by nurses in ICUs, as assessed by Corley’s instruments on moral distress (the Moral Distress Scale and the Moral Distress Scale–Revised). Additionally, this systematic review aimed to summarize the correlates of moral distress. Methods: A systematic search and review were performed using the following databases: Cumulative Index to Nursing and Allied Health Literature (CINAHL), the National Library of Medicine (MEDLINE/PubMed), and Psychological Abstracts Information Services (PsycINFO). The review methodology followed PRISMA guidelines. The quality assessment of the included studies was conducted using the Newcastle–Ottawa Scale. Results: Findings showed a moderate level of moral distress among nurses working in ICUs. The findings of this systematic review confirm that there are a lot of triggers of moral distress related to patient-level factors, unit/team-level factors, or system-level causes. Beyond the triggers of moral distress, this systematic review showed some correlates of moral distress: those nurses working in ICUs with less work experience and those who are younger, female, and intend to leave their jobs have higher levels of moral distress. This systematic review’s findings show a positive correlation between professional autonomy, empowerment, and moral distress scores. Additionally, nurses who feel supported by head nurses report lower moral distress scores. Conclusions: This review could help better identify which professionals are at a higher risk of experiencing moral distress, allowing the early detection of those at risk of moral distress, and giving the organization some tools to implement preventive strategies.
Workplace Bullying and Post-Traumatic Stress Disorder Symptomology: The Influence of Role Conflict and the Moderating Effects of Neuroticism and Managerial Competencies
Authors: Chenevert Miren , Vignoli Michela , Conway Paul M. , Balducci Cristian
Published: August 2022

Research has explored numerous consequences of workplace bullying, including a recent link to the exhibition of post-traumatic stress disorder (PTSD) symptomology. Role conflict as a workplace stressor may contribute to instances of bullying from a passive perspective, which may lead to PTSD symptomology in victims. What remains less explored is if role conflict has a direct relationship to PTSD symptomology and how personality traits such as neuroticism and workplace factors such as managerial competencies may moderate the stress brought on by role conflict. Hence the present study seeks to examine this gap in the literature. This study utilizes a between-subjects, cross-sectional design with 159 participants, 39.6% male and 60.4% female. Most participants (60%) were Italian workers of a large social cooperative organization. Confirmatory factor analysis indicated that the measurement model was valid and had an adequate model fit. Results from two separate moderated mediation analyses found a positive, full mediation between the independent variable of role conflict, the mediator of exposure to bullying, and the dependent variable of PTSD symptomology. Furthermore, in this study, neuroticism strengthened the indirect effect while managerial competencies weakened it. The results highlight the importance of training competent managers and providing resources for more vulnerable employees to moderate employee work stress and its negative outcomes.
Quality of Life and Mental Distress in Patients with Chronic Low Back Pain: A Cross-Sectional Study
Authors: Hnatešen Dijana , Pavić Roman , Radoš Ivan , Dimitrijević Iva , Budrovac Dino , Čebohin Maja , Gusar Ivana
Published: August 2022

The aim of this study was to examine the levels of health-related quality of life (HRQoL), pain intensity, and mental distress in participants with chronic low back pain (CLBP), and to examine the differences in the HRQoL of participants with respect to mental distress and the correlations of the examined variables. Data were collected from 148 patients using the SF-36 Health Status Questionnaire (SF-36), the Clinical Outcomes in Routine Evaluation–Outcome Measure (CORE-OM) questionnaire, and the visual-analog pain scale (VAS). The results indicate poorer self-assessment of physical health (Me = 28.1) compared to mental health (Me = 39.4). Participants with higher levels of mental distress reported significant emotional limitations (p = 0.003), lower energy (p < 0.001), poorer psychological health (p < 0.001) and social functioning (p < 0.001), more pain (p = 0.007), and, ultimately, poorer general health (p < 0.001). The level of mental distress was related to the level of HRQoL, while a correlation with the level of pain of the participants was not found. The study results indicate a connection between the presence of mental distress and almost all aspects of HRQoL in participants with CLBP.
A Social Return on Investment Evaluation of the Pilot Social Prescribing EmotionMind Dynamic Coaching Programme to Improve Mental Wellbeing and Self-Confidence
Authors: Makanjuola Abraham , Lynch Mary , Hartfiel Ned , Cuthbert Andrew , Wheeler Hayley T. , Edwards Rhiannon Tudor
Published: August 2022

The COVID-19 pandemic contributed to longer waiting lists for people seeking to access mental health services. The NHS Five Year Forward View encourages the development of empowerment-based social prescribing interventions to supplement existing mental health programmes. Based in South Wales, EmotionMind Dynamic (EMD) is a lifestyle coaching programme that supports individuals suffering from anxiety or depression. In this evaluation of lifestyle coaching, a mixed-method social return on investment (SROI) methodology was used to value quantitative and qualitative data from face-to-face and online participants. Data collection took place between June 2021 and January 2022. Participants included both self-referred clients and those referred from health services. Mental wellbeing data were collected at baseline and at the end of the programme using the short Warwick–Edinburgh Mental Wellbeing Scale (SWEMWBS) and the General Self-Efficacy Scale (GSES). Baseline and follow-up data were available for 15 face-to-face participants and 17 online clients. Wellbeing valuation quantified and valued outcomes from participants. Results indicated that for every GBP 1 invested, lifestyle coaching generated social values ranging from GBP 4.12–GBP 7.08 for face-to-face clients compared with GBP 2.37–GBP 3.35 for online participants. Overall, lifestyle coaching generated positive social value ratios for both face-to-face and online clients.
Fine-Grained Assessment of COVID-19 Severity Based on Clinico-Radiological Data Using Machine Learning
Authors: Liu Haipeng , Wang Jiangtao , Geng Yayuan , Li Kunwei , Wu Han , Chen Jian , Chai Xiangfei , Li Shaolin , Zheng Dingchang
Published: August 2022

Background: The severe and critical cases of COVID-19 had high mortality rates. Clinical features, laboratory data, and radiological features provided important references for the assessment of COVID-19 severity. The machine learning analysis of clinico-radiological features, especially the quantitative computed tomography (CT) image analysis results, may achieve early, accurate, and fine-grained assessment of COVID-19 severity, which is an urgent clinical need. Objective: To evaluate if machine learning algorithms using CT-based clinico-radiological features could achieve the accurate fine-grained assessment of COVID-19 severity. Methods: The clinico-radiological features were collected from 78 COVID-19 patients with different severities. A neural network was developed to automatically measure the lesion volume from CT images. The severity was clinically diagnosed using two-type (severe and non-severe) and fine-grained four-type (mild, regular, severe, critical) classifications, respectively. To investigate the key features of COVID-19 severity, statistical analyses were performed between patients’ clinico-radiological features and severity. Four machine learning algorithms (decision tree, random forest, SVM, and XGBoost) were trained and applied in the assessment of COVID-19 severity using clinico-radiological features. Results: The CT imaging features (CTscore and lesion volume) were significantly related with COVID-19 severity (p < 0.05 in statistical analysis for both in two-type and fine-grained four-type classifications). The CT imaging features significantly improved the accuracy of machine learning algorithms in assessing COVID-19 severity in the fine-grained four-type classification. With CT analysis results added, the four-type classification achieved comparable performance to the two-type one. Conclusions: CT-based clinico-radiological features can provide an important reference for the accurate fine-grained assessment of illness severity using machine learning to achieve the early triage of COVID-19 patients.
The Social Determinants of Adverse Childhood Experiences: An Intersectional Analysis of Place, Access to Resources, and Compounding Effects
Authors: Camacho Sayil , Henderson Sarah C.
Published: August 2022

Children across all races/ethnicities and income levels experience adverse childhood experiences (ACEs); however, historically excluded children and families must contend with added adversities across ecological levels and within higher-risk conditions due to systemic inequality. In this grounded theory study, the authors examined how health and social service providers (N = 81) from rural and urban counties in Tennessee provided services to low-income families, children exposed to opioids, and children of immigrants. Guided by an intersectional framework, the authors examined how rural and urban settings shaped higher risk conditions for ACEs and impeded access to resources at the individual, group, and community levels. Findings from this study identified additionally marginalized subpopulations and demonstrated how inequitable environments intersect and compound the effects of ACEs. The authors present their Intersectional Nature of ACEs Framework to showcase the relationship between high-risk conditions and sociopolitical and economic circumstances that can worsen the effects of ACEs. Ultimately, the Intersectional Nature of Aces Framework differentiates between ACEs that are consequences of social inequities and ACEs that are inflicted directly by a person. This framework better equips ACEs scholars, policymakers, and stakeholders to address the root causes of inequality and mitigate the effects of ACEs among historically excluded populations.
The First Exposure Assessment of Mercury Levels in Hair among Pregnant Women and Its Effects on Birth Weight and Length in Semarang, Central Java, Indonesia
Authors: Muniroh Muflihatul , Bakri Saekhol , Gumay Ainun Rahmasari , Dewantiningrum Julian , Mulyono Mulyono , Hardian Hardian , Yamamoto Megumi , Koriyama Chihaya
Published: August 2022

(1) Background: Methylmercury (MeHg) exposure during pregnancy is an important issue due to its possible adverse health effects on fetus. To contribute the development of assessment system of Hg exposure through fish consumption and health effects on children, we examined the hair Hg levels in pregnant women and birth weight and length. (2) Methods: In 2018, a cohort study was conducted on 118 pregnant women-infant pairs from six community health centers in the northern coastal area in Central Java Indonesia. Data on mothers’ characteristics during pregnancy, birth outcomes, and fish consumption were collected. Total Hg concentrations were determined from hair samples. (3) Results: The median (min-max) of the maternal hair Hg level was 0.434 (0.146–8.105) µg/g. Pregnant women living in lowland areas, near the sea, showed higher hair Hg concentration and fish consumption than those in highland areas {[0.465 (0.146–8.105) vs. 0.385 (0.150–1.956) µg/g; p = 0.043] and [(85.71 (0–500.0) vs. 49.76 (0.0–428.57) g/day; p < 0.01], respectively}. The maternal hair Hg level had no association with baby’s birth weight and length. (4) Conclusions: The median maternal hair Hg is at a low level and had no association with infant birth weight and length in this study subjects.
Impact of the “Warning Signs Campaign” on Characteristics of Patients Presenting with Acute Coronary Syndrome (ACS) to Hospitals
Authors: Redwood Eleanor , Hyun Karice , French John , Chew Derek , Kritharides Leonard , Brieger David
Published: August 2022

Objective: The National Heart Foundation’s Warning Signs Campaign (2009–2013) aimed to raise awareness amongst the public of Acute Coronary Syndrome (ACS), encouraging people to recognise suggestive symptoms and seek immediate medical attention. This study explores the impact of the campaign on the characteristics of patients presenting to hospitals around Australia with ACS. Design: Retrospective cohort analysis Setting: 10 Australian Hospitals recruiting for the CONCORDANCE registry continuously throughout the campaign period. Participants: Patients presenting with ACS to hospitals before, during and after the campaign ran in their jurisdiction. Main Outcome Measures: Whether an ambulance was called, time between onset of symptoms to first medical contact, as well as time between onset of symptoms to primary percutaneous intervention or lysis. Results: Time to first medical contact did not improve during or post-campaign for NSTEACS medical hours (IQI) 1.6 (0.5–4.8) pre, 2.2 (0.7–7.6) during, 2 (0.7–6.9) post (p < 0.001) or STEMI, 1.1 (0.4–3.5) pre, 1.6 (0.6–5.1) during, 1.4 (0.5–4.3) post (p = 0.0113). In STEMI, time from symptom onset to pPCI (p = 0.256) and time to lysis (p = 0.387) were also unchanged. The proportion of ambulance arrivals remained stable (pre 55% vs. during 58%, p = 0.493). Patients presenting during the campaign were more likely to be born in Australia 56% pre, 69% during, 68% post (p < 0.001), to report English as a first language 67% pre, 84% during, 79% post (p < 0.001), and had lower likelihood of prior MI or revascularization but greater likelihood of cardiovascular risk factors compared to those presenting prior. Conclusion: Among patients with ACS, we detected no increase in proportion of ambulance presentations nor earlier presentations among NSTEACS or STEMI during the campaign. There was an increase in the proportion of patients for whom English was the first language and those without a prior cardiac history but with cardiovascular risk factors, suggesting that the campaign impacted preferentially on certain strata in the community.
The Impact of Footwear on Occupational Task Performance and Musculoskeletal Injury Risk: A Scoping Review to Inform Tactical Footwear
Authors: Orr Robin , Maupin Danny , Palmer Robert , Canetti Elisa F. D. , Simas Vini , Schram Ben
Published: August 2022

The aim of this scoping review was to investigate the impact of footwear on worker physical task performance and injury risk. The review was guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews protocol and registered in the Open Science Framework. Key search terms were entered into five academic databases. Following a dedicated screening process and critical appraisal, data from the final articles informing this review were extracted, tabulated, and synthesised. Of 19,614 identified articles, 50 articles informed this review. Representing 16 countries, the most common populations investigated were military and firefighter populations, but a wide range of general occupations (e.g., shipping, mining, hairdressing, and healthcare workers) were represented. Footwear types included work safety boots/shoes (e.g., industrial, gumboots, steel capped, etc.), military and firefighter boots, sports shoes (trainers, tennis, basketball, etc.) and various other types (e.g., sandals, etc.). Occupational footwear was found to impact gait and angular velocities, joint ranges of motion, posture and balance, physiological measures (like aerobic capacity, heart rates, temperatures, etc.), muscle activity, and selected occupational tasks. Occupational footwear associated with injuries included boots, conventional running shoes, shoes with inserts, harder/stiffer outsoles or thin soles, and shoes with low comfort scores—although the findings were mixed. Occupational footwear was also linked to potentially causing injuries directly (e.g., musculoskeletal injuries) as well as leading to mechanisms associated with causing injuries (like tripping and slipping).
Prevalence and Associated Factors of Successful Ageing among People 50 Years and Older in a National Community Sample in Thailand
Authors: Anantanasuwong Dararatt , Pengpid Supa , Peltzer Karl
Published: August 2022

The aim of the study was to assess the prevalence and associated factors of successful ageing (SA) among people 50 years and older in Thailand. We analyzed national cross-sectional data (5092 men and women 50 years or older) from the Health, Aging and Retirement in Thailand (HART) study in 2015. The SA measures included (1) life satisfaction, (2) social engagement, (3) no major illness, (4) no probable depression, and (5) absence of functional disability. The sample included 5092 participants (median age 67 years, interquartile range 60 to 78 years). The prevalence of SA was 60.0% in adults 50 years and older, ranging from 43.8% in Krabi province to 80.2% in Pathum Thani province, 58.1% (≥60 years), and 56.3% (≥65 years), and the prevalence of the components of SA was 92.3% without major illness, 96.1% without functional disability, 87.5% without probable depression, 91.3% social engagement, and 82.3% high life satisfaction. In multivariable Poisson regression analysis, Buddhist religion (adjusted Prevalence Ratio (aPR): 1.50, 95% Confidence Interval (CI): 1.25 to 1.79), high subjective economic status (aPR: 1.29, 95% CI: 1.11 to 1.49), and physical activity (≥150 min/week) (aPR: 1.11, 95% CI: 1.01 to 1.24) were positively associated and increasing age (aPR: 0.993, 95% CI: 0.989 to 0.997) was negatively associated with SA. Almost two in three older adults in Thailand were successfully ageing. Factors associated with SA included being Buddhist, younger age, higher subjective economic status, and higher engagement in physical activity. These identified factors should be incorporated into health promotion intervention programs in Thailand.
Cognitive Function and the Ability to Operate Long-Term Oxygen Therapy Equipment: An Exploratory Study
Authors: Annaka Hiroki , Nomura Tomonori , Moriyama Hiroshi
Published: August 2022

Chronic respiratory disease patients with severe hypoxia receive long-term oxygen therapy (LTOT). The proper operation of LTOT equipment is essential for continuing treatment. This exploratory study investigated the relationship between cognitive impairment as a comorbidity in patients receiving LTOT and their ability to operate the LTOT equipment. The study measured responses to questions based on the ability of participants to operate the equipment and applied the Montreal Cognitive Assessment (MoCA). The ability of groups with MoCA scores ≤ 25 and >25 to operate LTOT equipment was compared to confirm the correlation between MoCA and ability to operate the equipment. An aggregate of 60 participants receiving LTOT were recruited, of whom 45 (75%) were MoCA score ≤ 25. The group of MoCA score ≤ 25 demonstrated a lower ability to operate LTOT equipment than group of MoCA score > 25 (p = 0.012). Additionally, a correlation was found between the ability to operate LTOT equipment and MoCA (rs = 0.743, p < 0.001). The results indicated that the group of MoCA score ≤ 25 indicated a lower ability to operate LTOT equipment than that of MoCA score > 25. Cognitive impairment in patients receiving LTOT can affect their ability to operate LTOT equipment.
Receiving Notification of Unexpected and Violent Death: A Qualitative Study of Italian Survivors
Authors: De Leo Diego , Guarino Annalisa , Congregalli Benedetta , Zammarrelli Josephine , Valle Anna , Paoloni Stefano , Cipolletta Sabrina
Published: August 2022

(1) Background: The loss of a significant person can be especially traumatic when death comes without warning and is due to causes such as suicide, murder and accidents. The way an individual is informed about the loss can affect the way of adapting to the loss and the quality of life of survivors. Communication modalities of the notifier may deeply influence the bereavement process. Aim: The present investigation aimed to explore the experience of those who received communication of such a type of death by a professional figure. (2) Method: Snowball sampling was used to recruit the participants to this qualitative study. Social networks, word of mouth and researchers’ acquaintances were used, including clients of the NGO De Leo Fund. A total of 52 Italian people (eight males and forty four females, mean age = 49.44; SD = 14.23) who received notification of the death of a loved one by police officers or by health professionals participated in the study. Deaths involved cases of suicide, murder, road accident and mountain accident. (3) Results: The following four key themes were identified: (a) how the communication took place; (b) reactions; (c) support; and (d) coping strategies. Only 22 participants reported having received clear information about the dynamics of what happened; the rest of the sample obtained only poor or ambiguous information. The majority of participants sought or received informal support from family and friends immediately after notification; however, some participants experienced a total lack of support. The opportunity to see the body of the loved one for the last farewell, when denied, caused discomfort in recipients of the news. (4) Conclusions: Even the impactful notification of a traumatic death such as suicide or road accident can be mitigated by the appropriate behaviour and attitude of notifiers, who should always avoid providing generic or ambiguous information about what happened. The notification process should not end with the simple transmission of the communication, but should also look at the following phases by including referral to supportive networks or bereavement services, aimed at assisting individuals in the immediate aftermath but also in the long term.
Progress in the Preparation and Modification of Zinc Ferrites Used for the Photocatalytic Degradation of Organic Pollutants
Authors: Zhu Jinyuan , Zhu Yingying , Chen Zhen , Wu Sijia , Fang Xiaojian , Yao Yan
Published: August 2022

Zinc ferrite is a type of photocatalytic material with high physicochemical stability, narrow band gap, high carrier separation efficiency, high porosity, and paramagnetism, which makes it easy to recover. Thus, zinc ferrite is widely used as a photocatalyst in water treatment. In this paper, the preparation principles as well as the advantages and disadvantages of typical methods used to prepare zinc ferrite including hydrothermal, co-precipitation, sol-gel, and other novel methods such as biosynthesis have been summarized. Modification methods such as elemental doping, composite formation, and morphological modification have been highlighted. Using these modification methods, the catalytic activity of zinc ferrite toward the photocatalytic degradation of organic pollutants in water has been enhanced. Biosynthesis is regarded as a promising preparation method that uses biological materials instead of chemical materials to achieve the large-scale preparation of zinc ferrite using low cost, energy efficient, and environmentally friendly processes. Meanwhile, the combination of multiple modification techniques to enhance the photocatalytic performance of zinc ferrite will be an important research trend in the future.