bluuebunny/crossref_metadata_2025 huggingface dataset:
Bakım Veren Bireylere Yönelik Geliştirilen Bireysel Ergoterapi Eğitim Programının Yaşam Kalitesine ve Bakım Veren Yüküne Yönelik Etkinliğinin İncelenmesi
Authors: KÖSE Barkın , AKI Esra
Published: February 2019

Amaç:
Çalışmanın amacı bakım veren bireylerin bakım verme işinden kaynaklanan
sorunlarını tespit etmek ve bu sorunların giderilmesini sağlamak için eğitim
modeli oluşturmaktır.

Gereç
ve Yöntem: Bakım veren bireylerin bakım verme işine
başladıktan sonra çeşitli alanlar da (fiziksel, psikolojik) problemler
yaşadıkları bakım veren bireyler tarafından ifade edilmiştir. Bu problemlerin
tespiti için yüz yüze görüşme yöntemi uygulanmıştır. Bu görüşmede bakım veren
bireylere yaşam kalitelerini belirlemek için Notthingam Sağlık Profili,
depresyon ve kaygı düzeylerinin tespiti için Beck Depresyon ve Anksiyete
Envanterleri, bakım veren yükünün tespiti içinde Zarit Yük İndeksi uygulandı.
Bu değerlendirme testleri analiz edilerek bireysel eğitim programları
hazırlandı ve bakım veren bireylere uygulandı. Eğitim programı sonunda
değerlendirme testleri ikinci kez uygulandı. Elde edilen veriler SPSS 22.0 veri
analiz programı kullanılarak yorumlanmıştır.

Sonuçlar:
Veri analizi sonucunda bakım veren bireylerin eğitim programı öncesi-sonrası
yaşam kalitelerinde(p < 0,043), depresyon düzeylerinde(p < 0,043) ve
bakım verme işinde kaynaklı yüklenme düzeyleri(p < 0,042) arasında
istatistiksel olarak anlamlı bir ilişki bulunmuştur.

Tartışma:
Bakım veren bireylerin bakım verme işine başladıktan sonra hayatları hızlı bir
şekilde değişmektedir. Bu değişim bakım veren bireyleri olumsuz etkilemektedir.
Bakım veren bireylerin yaşadıkları olumsuz koşuların üstesinden gelebilmesi
için yeterliliklerini artırmaları gerekmektedir. Bu noktada da bakım verenlere
yönelik uygulanan bireysel ergoterapi eğitim programlarının etkin olduğu
gözlenmiştir. Bu çalışmaların yaygınlaştırılması bakım veren bireylerin
yaşadığı sorunların çözümü noktasında önemli olduğu düşünülmektedir.
DISTANCE IN A DIALOGUE
Authors: Pilatova Valentina Nikolaevna
Published: February 2019

The article is devoted to one of the subtle mechanisms of speech - psychological distance between people during conversation. The purpose of the study is to substantiate the fact that an individual’s desire to avoid too close contact in communication with the interlocutor is an initial fact of life, which is represented in the text. We build distance in a dialogue in a hidden way. The novelty of the work is the description of the linguistic means by which one can create necessary distance in the course of communication. The author comes to the conclusion that adhering to the established distance in the dialogue allows a person to preserve identity and protect the intimate side of his/her life from idly curious people’s encroachments.
DIRECT IDENTIFIERS OF WOMAN’S ARTISTIC IMAGE IN JACK LONDON’S “COMPLETE COLLECTION NORTHERN TALES”
Authors: Sosnina Marina Aleksandrovna
Published: February 2019

The article presents a methodology for selecting language material. The notion “identifier” is revealed, and identifiers classification is presented. For the comprehensive study of woman’s artistic image in Jack London’s “Complete Collection Northern Tales”, an integrated approach is needed that will allow avoiding subjectivity in the material evaluation and ensure the accuracy and reliability of conclusions. The main attention is paid to the analysis of “direct identifiers”, which makes it possible to characterize the female characters fully, to understand the interpersonal relationships specificity, and uncover idea-thematic focuses.
SYSTEM OF SPATIAL PREPOSITIONS OF THE GERMAN LANGUAGE (CONCEPTUAL APPROACH)
Authors: Khoruzhaya Yuliya Nikolaevna
Published: February 2019

The article is devoted to the consideration of the features of the semantic functions of prepositions with spatial meaning in the German language from the point of view of the conceptual approach. The author gives a brief description of the system of prepositions expressing static and dynamic spatial relations in the German language, identifies semantic types of nouns in prepositional combinations. The focus of the work is on presenting ways to conceptualize spatial relations by native speakers. The paper suggests an algorithm for finding the necessary preposition of spatial meaning.
SEMANTIC PECULIARITIES OF SLANG UNITS (BY THE MATERIAL OF THE CHINESE LANGUAGE)
Authors: Afanas'eva Marina Petrovna
Published: February 2019

The article deals with one of the numerous definitions of the notion “slang”. Difference between neutral and colloquial vocabulary is identified. Slang units of the modern Chinese language are divided on the basis of their functions, and with the help of translation, their semantic peculiarities are shown. The author provides examples of the Chinese slang expressions that perform the cryptolalic function and phrases expressing attitude to a situation. The units used as a means of friendly teasing and cheering, designating by nationality, migrants, foreigners, attitude towards the state are singled out in separate groups. The vividness of the Chinese slang and ambiguity of its use are noted in the work.
I-IDENTIFICATION OF THE BEARERS OF THE RUSSIAN, CHINESE AND ARAB CULTURES
Authors: Balandina Ekaterina Sergeevna
Published: February 2019

The article discusses the ways of representing the image of “I” in the linguistic consciousness of the bearers of the Arabic, Chinese and Russian cultures. The object of the study is the linguistic consciousness of different cultures bearers. The subject of the research is the image of “I”. The results of the paper are based on the material obtained in the course of a free associative experiment. The analysis of the constructed associative fields of the stimulus word has made it possible to divide the obtained verbal reactions into the associations of contiguity and similarity, to identify the most frequent responses to the presented stimulus, to evaluate the value-emotional component of the image under study.
ATTEMPT OF ASPECTUAL MODELLING OF TEXTUAL COMPETENCE (BY THE EXAMPLE OF TEXTUAL COMPETENCE OF WRITTEN SPEECH ACTIVITY)
Authors: Nesmeyanov Aleksei Vladimirovich , Shadeko Vasilii Petrovich
Published: February 2019

The article is devoted to the analysis of textual competence from the standpoint of the linguistic, communicative and activity approaches to the text study. Textual competence is considered as synthesis of various linguistic and communicative competencies of a communicator. It is suggested that textual competence is conditioned by the type of speech activity. Therefore its constituent competences require different linguistic and communicative knowledge, abilities and skills from a communicator every time. The authors explicate their assumption by the example of the aspectual model of textual competence of written speech activity.
SYNTACTIC CONCEPT: CRITERIA AND METHODS OF ANALYSIS
Authors: Tsyganskaya Oksana Gennad’evna , Borisova Tat’yana Grigor’evna
Published: February 2019

The article deals with topical issues of the theory of syntactic concepts, analyses the use of the most adequate criteria and methods for the purpose of their application in the study of possible modal and local modifications of syntactic concepts. The novelty of the research is in the fact that a new classification of syntactic concepts has been proposed, the definition of a syntactic concept is elaborated. The obtained results can be used in studying the theory and practice of translation, in teaching a foreign language, in the field of artificial intelligence.
COMPARATIVE ANALYSIS OF DISAGREEMENT EXPRESSION MEANS IN THE ENGLISH AND CHINESE LANGUAGES
Authors: Deputatova Natal’ya Anatol’evna , Shangaraeva Liya Faridovna
Published: February 2019

The objective of the article is to identify and systematize the main characteristics of disagreement in the English and Chinese speech. The relevance of the choice of this topic is conditioned by the increased interest in the study of speech acts of disagreement in multi-structural languages. For the first time the authors present a semantic-pragmatic analysis of the examined direct and indirect speech acts of disagreement in the English and Chinese languages using examples of fiction. The results show that in most cases you can hear indirect initial replicas in the Chinese speech acts of disagreement; the British use both direct and indirect speech acts of disagreement.
FEATURES OF USING COMPENSATION STRATEGY IN ALLITERATION TRANSLATION
Authors: Mironova Galina Vladimirovna , Zueva Elena Anatol’evna , Ostapova Lyudmila Evgen’evna
Published: February 2019

The article deals with the use of the compensation strategy in the translation of puns, word play and characters’ contaminated speech. Particular attention is paid to the ways to preserve alliteration when translating a fiction text and the methods to compensate for the components of the semantic content. The use of multi-functional alliteration in a target text contributes to the preservation of the author’s stylistic and artistic intention. The analysis is based on the examples taken from the tale “The BFG” by the British writer Roald Dahl.
OBJECTIVATION OF NOTIONS ABOUT FAMILY IN THE RUSSIAN, ENGLISH AND CHINESE LANGUAGES
Authors: Selezneva Irina Aleksandrovna , Babina Lyudmila Vladimirovna
Published: February 2019

The article is devoted to the identification of the linguoculturological characteristics of notions about family in the Russian, English and Chinese languages. The paper presents the analysis of the concepts СЕМЬЯ, FAMILY, 家through the study of the language units objectifying these concepts. As a result of the analysis, the authors reveal the conceptual content of the concepts СЕМЬЯ, FAMILY, 家, which are the key ones in the Russian, English and Chinese linguocultures, and highlight similarities and differences between notions about family in the linguocultures under study.
FEATURES OF THE RUSSIAN LOCALIZATION OF THE FRENCH FILM TITLES
Authors: Tkacheva Anna Nikolaevna
Published: February 2019

The article contains the results of a comparative-contrastive analysis of the French film titles and their translations into Russian. The linguistic models of translation are presented in percentage. It is alleged that the proportion of the direct translation of the French originals is very high. Various subjective and linguistic-culturological factors, multiple tasks at localization are the cause of partial transformations. The substitutions of titles are performed due to the untranslatability of the title text or wordplay. The names of comedy films undergo the whole transformation more often than others.
IMAGE OF THE WEST IN THE MIRROR OF THE RUSSIAN PRESS: SPHERES-SOURCES OF METAPHORICAL EXPANSION
Authors: Abramova Elena Sergeevna , Subbotina Irina Mikhailovna , Klimova Yuliya Aleksandrovna
Published: February 2019

The study, carried out from the standpoint of the cognitive-discursive approach, is devoted to identifying and analysing the sources of metaphorical expansion that actualize the image of the West in the Russian press (by the material of the ‘Russian Federation Today’ magazine, 2016-2018). The most frequent spheres-sources of metaphorical representation are described: “War”, “Theatre”, “Game”. Their role in creating the image of the West among the Russian readers is determined. The authors ascertain a pragmatic potential of these spheres-sources and explicate the West assessments created by the magazine in question.
CONTENT OF THE TERM “COMMENTARY” IN A SCIENTIFIC TEXT AND IN USUAL USE
Authors: Akulova Arina Alekseevna
Published: February 2019

The article discusses the content of the term “commentary”. The purpose of the work is to identify the features of this term use in scientific literature, journalism and edition practice. For this, a component analysis of the definitions of the word “commentary” in explanatory dictionaries and an analysis of individual semes are carried out. The use of the term in textologists’ classifications is also investigated. It is hypothesized that differences in the use of this lexeme and, consequently, the term in various discourses are conditioned by the authors’ pragmatic attitude. The problem of difference in this term semantization by textologists and philologists is revealed.
VERBAL RECONSTRUCTION OF CRISIS EVENT IN NEWS MEDIA ONLINE MESSAGES
Authors: Ibrahim Iman Ali
Published: February 2019

The article is devoted to the problems and peculiarities of the formation of an event’s media image and its verbal reconstruction in news messages of the online media. Analysing the primary presentation of an event related to the Syrian crisis, the author comes to the conclusion that its verbal reconstruction in the news feeds of online publications is characterized by multiplicativity, language and stylistic nebulosity, syntactic redundancy, lexical repetitions, and the lack of integrity and completeness, which, in turn, leads to reliability violation and interference in information transition into knowledge.
LINGUISTIC FEATURES OF VLADIMIR ENOV’S PROSE FOR CHILDREN
Authors: Samokhvalova Ol’ga Pavlovna
Published: February 2019

The article describes the linguistic features of the prose for children by the indigenous writer Vladimir Enov, which fully reflects the Khanty’s worldview, the peculiarities of the national culture, life, language. The work is carried out directly on the basis of Vladimir Enov’s texts. The paper analyses the means of literary expression in his works, considers lexical and grammatical features, folklore motives, syntactic figures, stylistics and poetics of folk speech and studies the idiostyle peculiarities of the regional writer Vladimir Enov, which have become a subject of the special description for the first time.
FIGURATIVE DESCRIPTION OF FACIAL EXPRESSIONS (BY THE MATERIAL OF A. I. KUPRIN’S WORKS)
Authors: Yakimova Ekaterina Mikhailovna
Published: February 2019

The article discusses verbal ways of describing facial expressions in a fiction text. The author substantiates the proposition that linguistic conceptualization of nonverbal behaviour is associated with the expressive possibilities of the fiction language. Mimic actions (look, eye movements, smile) are represented by figurative nominations, such as metaphor, epithet, comparison, impersonation. Means of expression provide a detailed portrait description of a character, contribute to the detailed presentation of emotions and concretization of the author’s intention.
KINSHIP TERMS REFLECTING THE TUNDRA YUKAGIRS’ ANCIENT CULTURE
Authors: Kurilov Gavril Nikolaevich
Published: February 2019

The article presents the main results of the structural, semantic, and comparative-contrastive analysis of the kinship terms of the tundra and forest dialects of the Yukagir language with the aim of identifying the features of the most ancient composition of the proto-Yukagir family of languages. The objects of etymologization - the kinship terms эчиэ ‘father’, ииwаа ‘mother’- are considered as the original kinship terms of the tundra dialect of the Yukagir language for the first time. The nature of borrowing the Tungus kinship terms denoting father and mother is determined presumably. The semantic definition is given to the terms чумуочэ ‘father’s elder brother’, өчидиэ ‘uncle (father’s younger brother)’, чамийаа ‘grandmother (mother’s elder sister)’, йаадиэ ‘aunt (mother’s younger sister)’, the names of the closest relatives of father’s and mother’s generations. The article may be of interest to the researchers specializing in the Ural family of languages, since the Yukagir language belongs to the group of the Finno-Ugric and Samoyed languages.
ATTEMPT OF CREATING THE ASSOCIATIVE DICTIONARY OF COMPARISONS
Authors: Pyurbeev Grigorii Tserenovich , Golubeva Evgeniya Vladimirovna
Published: February 2019

The article publishes the results of a work carried out in the framework of the RFBR (Russian Foundation for Basic Research) project on the creation of a direct translation associative dictionary of comparisons. The process of preparing and conducting a mass associative experiment among the Kalmyk respondents is described, the resulting reactions are analysed. The paper discusses the principles of making dictionary entries. The work is accompanied by computerized methods for the synthesis and processing of information: the creation and generation of a questionnaire with stimuli, the input of reaction words and the formation of a statistical report. The conclusion is made about significant changes observed in the specificity of representative vocabulary and the image of the Kalmyks’ world identified on the basis of comparisons.
COMPOUND TOPONYMS WITH THE ZOONYMIC BASIS IN THE KARACHAY-BALKAR LANGUAGE AND THEIR LEXICAL AND GRAMMATICAL CHARACTERISTICS
Authors: Tekuev Mussa Maskhutovich , Khubolov Sakhadin Magametovich , Miziev Akhmat Magometovich
Published: February 2019

The article deals with compound (three-, four-, and five-word) toponyms with the zoonymic basis in the Karachay-Balkar language. Their structural-semantic and grammatical analysis is carried out, for derivative formations it is emphasized with the help of which affixes toponyms of this category are formed. The part-of-speech belonging of appellatives forming toponyms is noted, their motivational features connected with the spatial and parametric characteristics of geographic objects and use in economic activity are presented.
ANALYSIS OF METHODOLOGICAL APPROACHES IN THE DEVELOPMENT OF PHONETIC SKILLS OF TECHNICAL UNIVERSITY STUDENTS AT THE INITIAL STAGE OF TRAINING
Authors: Kargina Elena Mikhailovna
Published: February 2019

The article is devoted to the analysis of methodological approaches in the development of phonetic skills of technical university students at the initial stage of training. The disadvantages of the alphabetic-orthoepic introductory course of a foreign language, traditionally used in non-linguistic universities, are given. As an alternative, the phonetic-transcriptional course, the oral introductory course, the “word-sentence method” and the “sentence method” are considered, which are built on the holistic memorization of reading and graphics of words and sentences. The author analyses the methods of activating graphic forms and reading orally learned words.
LINGUO-DIDACTIC POTENTIAL OF SOCIAL ADVERTISING TEXTS IN TEACHING FRENCH TO LINGUISTIC UNIVERSITY STUDENTS
Authors: Ostroumova Ol'ga Fedorovna
Published: February 2019

The article identifies a linguo-didactic potential of social advertising texts in teaching French as a foreign language and justifies the reasonability of their usage as one of the most efficient means to form students’ communicative competence, creative thinking, informational and analytical skills. The use of social advertising texts promotes the formation of the value orientations and behavioural stereotypes of modern student youth in linguistic universities. The paper provides examples of social advertising texts use at French lessons.
METHODS OF USING A REGIONAL COMPONENT IN FOREIGN LANGUAGE TEXTBOOKS FOR HIGHER EDUCATIONAL ESTABLISHMENTS (BY THE EXAMPLE OF CULTURAL AND SYMBOLIC POTENTIAL OF MUROM)
Authors: Pankratova Elena Aleksandrovna
Published: February 2019

The article is devoted to the problem of using a regional component in foreign language textbooks to train future specialists to represent Russia in the situations of foreign-language cross-cultural communication and interaction within the home area. The suggested methods of using a regional component are of complex nature and include four aspects: pedagogical, axiological, methodological and culturological. Each of them is represented by relevant principles. A methodological model of culture as a system consisting of the complex of interconnected and interacting elements is offered.
LINGUO-CONCEPT-CENTRED LESSON IN THE SOLUTION OF THE PROBLEM OF A PUPIL’S ORAL SPEECH DEVELOPMENT
Authors: Truntseva Tat’yana Nikolaevna
Published: February 2019

The article deals with a linguo-concept-centred lesson built on the basis of the metasubject and linguoculturological approaches. The discussed didactic form is aimed at developing a pupil’s oral speech - a prepared monologic utterance, which is positioned by the author as the projection of a pupil’s individual holistic worldview in oral speech, translating the culture of comprehending scientific and artistic worldviews through solving linguoculturological problems, i.e. the lexical, derivational, etymological analysis of universal concepts.
DEVELOPMENT OF THE RUSSIAN SPEECH AND CROSSCULTURAL COMPETENCE OF THE CHINESE STUDENTS BY MEANS OF PAINTING IN DISTANCE LEARNING
Authors: Yang Chunlei , Khodyakova Liya Aleksandrovna
Published: February 2019

The article substantiates the idea that in distance learning, the use of the program for videoconferencing ‘BigBlueButton’ is the most efficient way to develop the Russian speech and crosscultural competence of the Chinese students. The authors focus on the creation of speech environment by means of visual aids and the method of frontal conversation based on the reproduction of a painting. The paper offers an online lesson plan using the reproduction of the painting “Unexpected Visitor” by I. Ye. Repin, the artist’s biography, Ernst Sapritskii’s poem of the same name and reference materials.
POETICS OF CHRONOTOPE OF G. R. DERZHAVIN’S ODE “MORNING” IN N. M. KARAMZIN’S “BULLETIN OF EUROPE”
Authors: Ratnikova Ol’ga Evgen’evna
Published: February 2019

The article presents an analysis of the chronotope peculiarity in the ode “Morning” by G. R. Derzhavin, which is revealed in the symbolism of daily time. For the first time in literary studies, the paper considers the issue of the reason for the publication of this particular ode apart from “To God”, with which “Morning” constitutes a dilogy, in the “Bulletin of Europe” by N. M. Karamzin, whose creative interaction with Derzhavin had counted more than ten years by 1802. Literary originality of the ode is studied; special attention is paid to the colour and sound writing. Various interpretations of the ode are offered: the author’s (by Derzhavin), in which the image of the morning symbolizes the divine origin of the world, and the publisher’s (by Karamzin), implying a symbol of enlightenment by the image of the morning.
LITTLE MAN’S TRAGEDY IN THE GREAT WAR (BASED ON THE KARACHAY-BALKARIAN EXPATRIATE COMMUNITY’S PROSE)
Authors: Bittirova Tamara Shamsudinovna
Published: February 2019

The article analyses the main genres of the Karachay-Balkarian expatriate community’s prose, the problematic of the prose works. It reveals the factors that influenced the formation of the prose, as well as its specificity in comparison with the poetic genres implemented in the diaspora’s literature. The paper presents an analysis of the plots and motives of the Karachay-Balkarian expatriate community’s prose works. The author pays special attention to the story “The Damned Glade” by H. Botash and its lyrical hero, who found himself in the epicentre of the tragedy that took place in late May - early June, 1945 on the banks of the Austrian river Drau and the nearby forests.
CONTRAST ROLE IN A FICTION WORK COMPOSITION (BY THE MATERIAL OF F. SCOTT FITZGERALD’S SHORT STORY “THE BABY PARTY”)
Authors: Voeikova Anna Andreevna
Published: February 2019

The article is devoted to the analysis of contrast role in a fiction work construction. As material for the research, the short story genre has been chosen, namely F. Scott Fitzgerald’s story “The Baby Party”, which is considered in this perspective for the first time, and it determines this study novelty. Basing on the dictemic theory of the text, the author proves the multi-contrast nature of the dictema that is confirmed by examples at the structural (syntactic), semantic, and compositional levels. The latter is particularly replete with contrast elements: opposition of speech types, opposition of characters, and change in the narrative planes. All these things make contrast an expressive and meaningful technique in a fiction work construction.
REVIEW OF THE BOOK “MNEMOSYNE’S GIFT. NABOKOV’S NOVELS IN THE CONTEXT OF THE RUSSIAN AUTOBIOGRAPHICAL TRADITION” BY B. V. AVERIN
Authors: Nyubina Larisa Mikhailovna , Andreev Vadim Sergeevich
Published: February 2019

The review offers a detailed description of the book “Mnemosyne’s Gift. Nabokov’s Novels in the Context of the Russian Autobiographical Tradition” by B. V. Averin. B. V. Averin’s work is devoted to the autobiographical genre in the Russian literature, its features, and also represents a deep analysis of the majority of V. Nabokov’s works from the point of view of autobiographical art. The book covers the main theoretical problems of the autobiographical genre: three-side unity of the author, the intermediate position of autobiographical texts, the multiple “I” phenomenon, the classification of certain types of autobiography, the analysis of the autobiographical creativity of different authors.
“ANALYTICAL ARTICLE” GENRE (BY THE EXAMPLE OF TEXTS OF THE ENGLISH-LANGUAGE QUALITY PRESS)
Authors: Nikonova Ekaterina Andreevna
Published: February 2019

The paper reveals the genre-forming features of the “analytical article” genre. This type of text is characterized differently in foreign and domestic linguistics, however, despite national and cultural specificity, it reveals common features. By its nature, the “analytical article” is an objective genre aimed at informing readers, but under the influence of political discourse there is an increase in the subjective component, and, as a result, in the impacting function. This double nature of the genre is represented in linguistic means used by the author.
Идентификация компонентов комплексного фитопрепарата ангионорм методом сверхвысокоэффективной жидкостной хроматографии с масс-спектрометрическим детектированием
Authors: Стручков Петр Андреевич , Мельников Евгений Сергеевич , Белобородов Владимир Леонидович , Колхир Владимир Карлович , Воскобойникова Инна Васильевна
Published: February 2019

Ангионорм — оригинальный отечественный препарат на основе высушенного 25 % водно-этанольного экстракта смеси лекарственного растительного сырья: семян (плодов) конского каштана обыкновенного (Aesculus hippocastanum L.), корней солодки голой (Glycyrrhiza glabra L.), плодов боярышника (Crataegi) и плодов шиповника (Rosae). Разработана методика идентификации основных компонентов экстрактов смеси и каждого вида сырья методом ВЭЖХ-МС-МС в обращённо-фазовом варианте с градиентным режимом элюирования. С помощью стандартных образцов идентифицировано 15 соединений различных классов (феноло- и гидроксикоричные кислоты и их эфиры, флавоноиды, гликозиды флавоноидов, тритерпеновые сапонины). С использованием MRM-переходов, порядка элюирования и литературных данных идентифицированы пики изомеров гиперозида, ликвиритина, β-глицирризиновой кислоты, эсцина. Определены растительные источники идентифицированных компонентов, предложены маркерные соединения, характеризующие каждый вид сырья в экстракте смеси.
Изучение растворимости кетопрофена из твердых дисперсий с полиэтиленгликолями
Authors: Беляцкая Анастасия Владимировна , Краснюк (мл.) Иван Иванович , Краснюк Иван Иванович , Степанова Ольга Ивановна , Кошелева Татьяна Михайловна , Кудинова Татьяна Павловна , Воробьев Александр Николаевич , Марянян Моника Мехаковна
Published: February 2019

Определено влияние твердых дисперсий (ТД) на растворимость нестероидного противовоспалительного средства — кетопрофена. Исследованы кетопрофен и его ТД с полиэтиленгликолями -400, -1000, -1500, -2000 и -3000. Получение ТД повышает растворимость и скорость растворения кетопрофена. Растворимость кетопрофена из ТД увеличилась в 1,2 – 1,8 раза. Скорость растворения из ТД повышается в 1,7 – 2,4 раза. Предполагается, что улучшение высвобождения кетопрофена из ТД происходит за счет комплекса факторов: солюбилизации и аморфизации вещества, образования межмолекулярных водородных связей. Полученные результаты могут быть использованы при разработке быстрорастворимых твердых ЛФ кетопрофена.
Синтез, противоопухолевая и антибактериальная активность новых производных дигидронафталина и дигидробензо[h]хиназолина
Authors: Маркосян Ашот Ишханович , Айрапетян Карине Камоевна , Габриелян Сирануш Амбарцумовна , Мамян Сурен Серёжаевич , Ширинян Валерик Зармикович , Захаров Алексей Владимирович , Арсенян Флора Гайковна , Авакимян Джулиета Ашотовна , Степанян Грачик Мовсесович
Published: February 2019

Разработан метод синтеза 1-амино-3,3-диметил-3,4-дигидронафталин-2-карбонитрила (β-аминонитрил), исходя из которого синтезированы шиффовы основания, тиоуреидо- и хлорацетамидопроизводные. Последний циклизован в 5,5-диметил-2-хлорметил-5,6-дигидробензо[h]хиназолин-4(3H)-он, исходя из которого синтезированы некоторые 2-сульфанилметил- и 2-аминометилпроизводные. Выявлено, что 2-хлорметилбензо[h]хиназолин в присутствии основания образует конденсированное гетероциклическое соединение из 7 циклов — 1,1,11,11-тетраметил-1,2,11,12-тетрагидропиразино[2,1-b:5,4-b’]ди(бензо[h]хиназолин)-10,16(8H,18H)-дион. Изучены противоопухолевые свойства синтезированных соединений на модели асцитной карциномы Эрлиха и антибактериальные свойства по методу «диффузия в агаре».
Оценка хронической токсичности препарата глипин в эксперименте на крысах
Authors: Трещалин Иван Дмитриевич , Голибродо Василиса Антоновна , Трещалин Михаил Иванович , Переверзева Элеонора Рафаиловна
Published: February 2019

На аутбредных крысах самках и самцах проведено токсикологическое изучение нового рекомбинантного биомодифицированного глюкагоноподобного пептида человека — препарата глипин, разработанного в ФГУП «ГосНИИгенетика». Глипин вводили ежедневно подкожно в течение 168 дней в разовых дозах, составляющих 1 и 10 терапевтических (0,1 и 1 мг/кг). В ходе исследования определяли массу тела животных, проводили клинический и биохимический анализ крови, анализ мочи, регистрировали ЭКГ. На 1 и 30 сут после окончания курса по 5 животных из каждой группы подвергали эвтаназии. При вскрытии определяли массовые коэффициенты сердца, печени, почек, селезенки и вилочковой железы, проводили патоморфологическое исследование внутренних органов. Показано, что длительное введение препарата вызывает задержку прироста массы тела в среднем на 10 % (p ≤ 0,05) и приводит к достоверному снижению содержания белка в сыворотке крови в среднем на 20 % (p ≤ 0,05). При патоморфологическом исследовании установлено, что при 10-кратном превышении терапевтической дозы препарат вызывает обратимые изменения структуры тканей почек и поджелудочной железы.
Участие нейроглии в патогенезе шизофрении и действии антипсихотических средств
Authors: Арушанян Эдуард Бениаминович
Published: February 2019

Согласно современным данным, психические расстройства при шизофрении могут быть сопряжены с нарушением не только в деятельности центральных нейронов и связанных с ними нейромедиаторных систем, но также с патологическими процессами в нейроглии. Дефекты в морфологии и функции каждой из основных популяций нейро-глиальных элементов (астроцитах, микроглии, олигодендроцитах) могут отвечать за различные проявления шизофрении и эффект антипсихотических веществ.
METAPHORS IN THE HEADINGS OF KALTIM POST NEWS
Authors: Soleha Irma
Published: February 2019

Metaphors used in the political news published in Kaltim Post Daily News are analyzed in this study.  The objectives of the analysis are to see kind of metaphors and their intended meaning in the context of news.  Content analysis is used for the design in this study.  Data are collected from available news published in October to November 2008.  Criteria of metaphors as proposed by Wahab (1995) are used for analysis.  This study identified two kinds of metaphors among three kinds proposed by Wahab (1995).  The first kind is nominative metaphors used as a subject of a sentence.  The second kind is a predictive metaphor used for a predicate of a sentence.  In the context of lead presentation in of news in publication, the use of nominative and predicative metaphors are relevant to the uses of precise diction in the limited space of publication.               Keywords:  metaphors, predicative, nominative, news, lead.
PENGARUH PEMBERIAN TERAPI BERMAIN TERHADAP PEMBELAJARAN MITIGASI BENCANA PADA ANAK AUTIS BERBASIS DISASTER NURSING COMPETENCY
Authors: Indriasari Fika Nur , Widyarani Linda , Kusuma Prima Daniyati
Published: February 2019

Background: A powerful earthquake in Yogyakarta, causing major damage and many deaths. Children with autism are more vulnerable and have a greater risk of earthquake because they are have an intellectual, social and verbal disability to safe life independently.

Objective: This research discussed the influence of play therapy on learning of disaster mitigation for children with autism.

Method: This research used qualitative descriptive design and consider a sample of 30 children with autism in SLB N Pembina Yogyakarta. Play therapy in this research use drawing and coloring methods, also watching video about disaster preparedness.

Results: Play therapy could effectively be applied as earthquake mitigation lesson to children with autism in SLB N Pembina Yogyakarta. Before interventions, there were 2 children (7%) able to draw on actions when an earthquake occurred, and increased to 19 children (63,33%) after interventions.

Conclusion: Play therapy could be effectively applied to children with autism as earthquake disaster mitigation showed by an increase of children’s drawing and coloring ability on actions when an earthquake occurred for as much as 56,33%.

 

Keyword: Children with autism, mitigation ability, play therapy
PENGARUH PEMBERIAN INFORMASI DENGAN APLIKASI WHATSAPP TERHADAP PENGETAHUAN REMAJA TENTANG HIV DAN AIDS
Authors: Kurniawati Herlin Fitriana , Diniyah Kharisah
Published: February 2019

Background: Yogyakarta has crucial health problem which is the rise of free sex incidence on youth which can lead to HIV and AIDS. One strategy to overcome this problem is by providing correct and easily accessible information of HIV/AIDS. Submission of the information is done through WhatsApp group application by considering the number of users and ease of information access through the application.

Objective: This study aimed to investigate the effect of information intervention using whatsapp on youth knowledge regarding HIV and AIDS in the Temon Kulon Progo district of Yogyakarta.

Methods: A pre-experimental study with one group pretest and post test design was applied to 50 respondents using purposive sampling. Data were gathered by employing questionnaires and then analized by using Wilcoxon Matched Pairs test.

Results: The results showed that there was an effect of giving information with whatsapp application to adolescent knowledge about HIV and AIDS in the Temon Kulon Progo district of Yogyakarta (z=-6,193; p<0,05).

Conclusion: Information intervention by using WhatsApp can escalate the knowledge of youth regarding HIV and AIDS.

Keywords: HIV and AIDS, Whatsapp, Teenagers
Do Suspensions Affect Student Outcomes?
Authors: Lacoe Johanna , Steinberg Matthew P.
Published: February 2019

Discipline reformers claim that suspensions negatively affect suspended students, while others suggest reforms have unintended consequences for peers. Using student panel data from the School District of Philadelphia, we implement student fixed effects and instrumental variable (IV) strategies to examine the consequences of suspensions for offending students and their peers. A suspension decreases math and reading achievement for suspended students. The effects are robust to IV estimates leveraging a district-wide policy change in suspension use. Suspensions are more salient for students who personally experience suspension than for their peers. Exposure to suspensions for more serious misconduct has very small, negative spillovers onto peer achievement, but does not change peer absences.
Teaching kinematic graphs in an undergraduate course using an active methodology mediated by video analysis
Authors: Vaara Riikka-Liisa , Gomes Sasaki Daniel Guilherme
Published: February 2019

This work address the preconceptions of first year engineering students about the kinematic graphs and the outcomes of a pedagogical strategy that relies on Predict – Observe – Explain learning method mediated by a video analysis software. The whole learning procedure was accompanied by a written material as students’ worksheets which enabled a formal record of the students’ conceptions throughout the process. The Test of Understanding of Kinematics Graphs was utilized to evaluate the students’ preconceptions and learning gains. It was found that first year engineering students had serious difficulties in drawing and interpreting kinematic graphs. Although interpretation of graphs and the understanding of the velocity and acceleration concepts improved, the preconceptions were quite resilient.
Perlindungan hak cipta bagi pengunggah video YouTube yang di gunakan oleh stasiun televisi
Authors: Zulkarnain M Fadel
Published: February 2019

Video adalah merupakan salah satu karya cipta yang dilindungi oleh hak cipta oleh Undang-Undang, yaitu adalah Undang-Undang Nomor 28 Tahun 2014 tentang Hak Cipta. Namun dalam prakteknya sering sekali masih terjadi pelanggaran-pelanggaran terhadap karya hak cipta video yang merupakan hak milik dari seorang pencipta, salah satu pelanggaran nya adalah pada saat video tersebut diunggah ke dalam suatu situs internet yaitu Youtube. dan video tersebut di tayangkan di televisi tanpa izin dari pencipta video. Permasalahan yang timbul sekarang adalah bagaimana pengaturan hubungan hukum antara youtube dengan stasiun televisi, bagaimana tanggung jawab stasiun televisi terhadap youtube atas video yang diunggah di televisi, bagaimana perlindungan hak cipta menurut undang-undang nomor 28 tahun 2014 tentang hak cipta terhadap pencipta video yang diunggah di youtube yang di tayangkan di televisi. Penelitian ini menggunakan metode penelitian hukum normatif yang bersifat deskriptif kualitatif, yakni pendekatan dari sudut pandang menurut ketentuan hukum dan ketentuan peraturan perundang-undangan yang berlaku. Dari hasil penelitian ini bahwa situs youtube sudah memberikan syarat dan ketentuan bagi pengunggah video, dan dengan adanya aturan tersebut maka akan timbul hubungan hukum dan akan melahirkan hak dan kewajiban bagi pencipta video maupun kepada stasiun televisi sebagai pihak ketiga yang mengambil video dari youtube yang ditayangkan di stasiun televisi dengan diambilnya video tersebut maka pihak stasiun televisi haruslah mendapatkan izin terlebih dahulu kepada pencipta video tersebut dan mencantumkan courtesy of youtube (bersumber dari youtube) dan nama pencipta video. Adapun dari keuntungan yag didapat oleh stasiun televisi dengan menyiarkan video tersebut secara komersial stasiun televisi juga harus memberikan sebagian keuntungan (royalti) terhadap pencipta video. Kata Kunci : Hak Cipta, Video, Perlindungan Hukum
Mendelian Disease caused by variants affecting recognition of Z-DNA and Z-RNA by the Zα domain of the double-stranded RNA Editing Enzyme ADAR
Authors: Herbert Alan
Published: February 2019

Variants in the human double-stranded RNA (dsRNA) editing enzyme ADAR produce three well-characterized rare Mendelian Diseases: Dyschromatosis Symmetrica Hereditaria (DSH)(OMIM: 127400), Aicardi-Goutières syndrome (AGS)(OMIM: 615010) and Bilateral Striatal Necrosis/Dystonia (BSD). ADAR encodes p150 and p110 protein isoforms. p150 incorporates the Zα domain that binds left-handed Z-DNA and Z-RNA with high affinity through contact of highly conserved residues with the DNA and RNA double-helix. In certain individuals, frameshift variants on one parental chromosome in the second exon of ADAR produce haploinsufficiency of p150 while maintaining normal expression of p110. In other individuals, loss of p150 expression from one chromosome allows mapping of Zα p150 variants from the other parental chromosome directly to phenotype. The analysis reveals that loss of function Zα variants cause dysregulation of innate interferon responses to dsRNA. This approach confirms a biological role for the left-handed conformation in human disease, further validating the power of Mendelian genetics to provide unambiguous answers. The findings reveal that the human genome encodes genetic information using both shape and sequence.
PATEN UNTUK STUDI KASUS SMARTPHONE MOTOROLA LIPAT
Authors: rahmadi putra
Published: February 2019

muncul sebuah brand legendaris yang kini telah dimiliki oleh Lenovo, Motorola yang membawa oase segar dalam persaingan teknologi yang sudah lama stagnan ini.paten ini sudah resmi diajukan pihak Motorola sejak September 2016. Sehingga, secara tidak langsung manufaktur yang berbasis di AS ini bisa digolongkan ke dalam jajaran brand gelombang awal yang memrakarsai konsep ponsel lipat.
Replication and Transparency of Qualitative Research from a Constructivist Perspective
Authors: TalkadSukumar Poorna , Metoyer Ronald
Published: February 2019

The positivist or conventional notion of replication does not lend itself to qualitative research. However, defining replication in line with the nature of qualitative inquiry and its interpretive strengths can lead to many opportunities including creating multiple discourses of the same phenomenon and comparing the effectiveness of different methods. We define what a replication of a qualitative study can potentially entail and espouse that such replications should, by all means, be attempted. Towards these goals, we also advocate open practices in qualitative research to make more apparent the iterative and emergent processes typical of qualitative studies that are often indiscernible from their published reports.
PROTECTION AGAINST NETWORK SECURITY PROBLEMS AND NETWORK ATTACKS// Journal of Technical and Natural Sciences 1(10), 2019/ OEAPS Inc.(Open European Academy of Public Sciences); Chief Editor Vitaly Yakovlev- Berlin, Germany. 26.01.2019: OEAPS Inc., 2019. - pp. 41-48.
Authors: Ziyadullayev Zukhriddin Ilkhom ugl , Qudratova Mekhriniso Ne'mat qizi , Salimova Khusniya Rustamovna , Kamoliddinova Feruza Kamoliddin qizi
Published: February 2019

This paper explores safe and trouble-free use of networks. It introduces how we can protect our information and what we need during using internet. How they can attack the Internet, how to protect them. The use of the Internet is harmful and beneficial. We can find out what results can be achieved through our protection.
Pengaturan Hak Paten Pada Industri Indonesia
Authors: Febriyan Dedy
Published: February 2019

Pengaturan-pengaturan dalam kekayaan dan hasil dari pemikiran masyarakat atau warga negara bahkan budaya yang terlahir sejak zaman dulu hingga sekarang harus selalu dilestarikan dan dilindungi agar tetap terjaga dan selalu ada sampai generasi-generasi penerus bangsa kita jangan sampai kekayaan kita dan budaya yang telah ada dari turun temurun diambil oleh bangsa lain apalagi negara-negara tetangga kita sendiri. Perkembangan teknologi yang sangat pesat dizaman globalisai ini , menuntut kita sebagai warganegara indonesia ikut dalam mengembangkan terobosan teknologi yang belum ada sebelumnya , yang pasti teknologi yang lebih canggih , efisien dan ramah lingkungan pastinya .Hasil-hasil pemikiran bangsa kita harus dapat diakui kelegalannya oleh pihak internasional yaitu dengan cara perlindungan Hak Paten , perlindungan ini sangat penting demi pengakuan bangsa kita dimata bangsa-bangsa lain , demi membuktikan kepadanya bahwa bangsa kita juga bisa mengikuti perkembangan teknologi , bukan hanya mengikuti tapi menciptakan teknologi yang modern yang belum ada sebelumnya.Pengaturan Hak Paten diatur oleh undang-undang kepemerintahan indonesia yang mendapftarkan hasil-hasil pemikiran bangsanya kepada lembaga Hak Paten internasiaonal dengan cara perancangan undang-undang dan pembuatan prosedure tata cara pendaftarannya dan kategori-kategori perkembangannya .
UAS HAKI ERWIN GUSTIAWAN TINDAK PIDANA PELANGGARAN DESAIN INDUSTRI MENURUT UNDANG-UNDANG NOMOR 31 TAHUN 2000
Authors: gustiawan erwin
Published: February 2019

Hak Kekayaan Intelektual didefinisikan sebagai suatu perlindungan hukum yangdiberikan oleh Negara kepada seseorang dan atau sekelompok orang ataupun badanyang ide dan gagasannya telah dituangkan ke dalam bentuk suatu karya cipta(berwujud). Karya Cipta yang telah berwujud tersebut merupakan suatu hak individudan atau kelompok yang perlu dilindungi secara hukum, apabila suatu temuan(inovasi) tersebut didaftarkan sesuai dengan persyaratan yang ada.Karya cipta yang berwujud dalam cakupan kekayaan intelektual yang dapatdidaftarkan untuk perlindungan hukum yaitu seperti karya kesusastraan, artistik, ilmupengetahuan (scientific), pertunjukan, kaset, penyiaran audio visual, penemuanilmiah, desain industri, merek dagang, nama usaha, dll.Kata Kunci : UU No 31 Tahun 2000, Information Technology
Nonlinear dynamics and performance enhancement of asymmetric potential bistable energy harvester
Authors: Bowen Chris
Published: February 2019

Bistable systems exhibiting complex dynamic behaviors have been viewed as efficientmethods to overcome the issue of linear energy harvesters only performing well near their resonance frequencies. Moreover, performance enhancement strategies of bistable energy harvesters have been extensively discussed for perfectly symmetric potentials. Due to imperfects caused by non-uniform manufacturing of the harvester, eccentricity of the buckling or magnetic force, and uneven gravity, dynamic characteristics and performance enhancement of asymmetric potential energy harvesting remain an open issue. Therefore, this paper investigates the influence mechanism and performance enhancement method of cantilever-based bistable energy harvesting systems with asymmetric potentials. Bifurcation diagram is employed to discover the effect of asymmetric potentials on the output response of the dimensionless electromechanical equation. Based on the numerical results, a performance enhancement method is proposed by compensating the asymmetric potentials with a proper bias of the system for decreasing the negative impact of asymmetric potentials on bistable energy harvesting. The optimum bias angle is derived and numerical simulations under constant and sweep frequency excitations demonstrate that the performance of the asymmetric potential BEHs is enhanced in a certain bias angle range around the optimum value.
uas haki wahyu ferdiansyah NORMA-NORMA HUKUM PADA UU NO 31 TAHUN 2000
Authors: ferdiansyah wahyu
Published: February 2019

Hak Kekayaan Intelektual didefinisikan sebagai suatu perlindungan hukum yangdiberikan oleh Negara kepada seseorang dan atau sekelompok orang ataupun badanyang ide dan gagasannya telah dituangkan ke dalam bentuk suatu karya cipta(berwujud). Karya Cipta yang telah berwujud tersebut merupakan suatu hak individudan atau kelompok yang perlu dilindungi secara hukum, apabila suatu temuan(inovasi) tersebut didaftarkan sesuai dengan persyaratan yang ada.Karya cipta yang berwujud dalam cakupan kekayaan intelektual yang dapatdidaftarkan untuk perlindungan hukum yaitu seperti karya kesusastraan, artistik, ilmupengetahuan (scientific), pertunjukan, kaset, penyiaran audio visual, penemuanilmiah, desain industri, merek dagang, nama usaha, dll.Kata Kunci : UU No 31 Tahun 2000, Information Technology