bluuebunny/crossref_metadata_2025 huggingface dataset:
The use of azithromycin and pyrimethamine for treatment of cerebral toxoplasmosis in human immunodeficiency virus-infected patients: a systematic review
Authors: Ramos Mark Erving H. , Villaraza Steven G.
Published: March 2023

Purpose Toxoplasma gondii is a parasite that is widely distributed around the globe and can cause brain inflammation, particularly in immunosuppressed patients such as those diagnosed with human immunodeficiency virus (HIV). This paper reviews the efficacy of azithromycin and pyrimethamine combination therapy for cerebral toxoplasmosis in patients with HIV.Methods The scope of the studies included in this review was limited from 1992 to 2022, with studies primarily being randomized, controlled clinical trials available on online scientific journal databases. The authors screened eligible records for review, removing those that did not fit the inclusion and exclusion criteria. The risk of bias of the extracted data was analyzed through the Cochrane risk-of-bias tool for randomized trials.Results A broad search of major online databases such as PubMed, Medline, Google Scholar, and Cochrane using keywords, limit fields, and Boolean operators yielded 3,130 articles. After thoroughly screening the search results, two studies were included in this review. Results from the studies included in the review demonstrate that the combination therapy of azithromycin and pyrimethamine is favorable for cerebral toxoplasmosis. However, the net response is less effective than the standard treatment regimen (pyrimethamine and sulfadiazine).Conclusion The combination therapy of azithromycin and pyrimethamine is less effective than the standard treatment regimen for maintenance therapy for cerebral toxoplasmosis; thus, administering these medications for this indication must be met with caution.
Capacity Building for Food Safety Practices in Fish Farmers in Bangladesh: A Problem-Based Learning Approach
Authors: Dillon M. , Heap J. , Patel D. , Khan D.
Published: March 2023

Purpose: This paper discusses how a problem-based learning (PBL) approach can be used effectively to resolve problems in food safety standards being adopted by fish farmers in Bangladesh. Using the example of a Food and Agriculture Organization (FAO) Food Safety Programme, this paper further highlights the potential of PBL to promote the capabilities needed to train multiple stakeholders, including staff working in local, district, and national organisations, and for local fish farmers to apply the FAO Food Safety Code of Practice in their farms. Design/Methodology/Approach: A qualitative intrinsic case study approach with qualitative content analysis of written reports was adopted to assess and provide an in-depth description of the PBL programme, the potential capabilities developed and the impact(s) of the project. Findings/Results: The PBL approach adopted for training multiple stakeholders was based on the teaching learning theory of social constructivism using a cascade model of training. Drawing on these principles, the training has promoted capacity building in the different levels of the cascade model, empowered fish farmers to change their behaviours, and adopt the FAO Food Safety Code of Practice, and enhanced their business quality and performance as well as food safety control. Moreover, the success of the training programme enabled it to be extended to a further 100,000 fish farms, and the same approach has been adopted in other types of farms, such as poultry and crop farms. Originality/Value: This paper provides a clear understanding how a PBL approach is capable of outscalling capacity building and amplifying sustainable impact by developing collaborative partnerships with different actors in the fishery sector to bring positive changes in communities that they support. Paper Type: Case study.
Effect of Camera Calibration Refreshing on Orthophoto Position Accuracy in UAV Mapping
Authors: ŞAHİN Cumhur
Published: March 2023

Unmanned aerial vehicles (UAVs) are autonomous or remote control controlled air vehicles without a pilot. UAVs are aerial platforms capable of carrying non-metric photogrammetric equipment. In this study; the effect of two different calibration values of the camera available on the DJI Phantom 4 Pro equipment to the ortho-photo maps obtained from two different flight heights was investigated. An area within the campus of Gebze Technical University was chosen as a study area. PI 3000 software was used to calibrate the camera and the differences between the calculated parameters and the conventional parameters were determined. Also, the effect of the parameters on position accuracy was investigated. In the photogrammetric stereo model, the rms of Z depends on the picture scale, flight height, base length and the measurement accuracy of image coordinates. Since the measurement accuracy of the image coordinates x, y is also affected by the calibration accuracy, the calibration field independent of the Z value can be used. Geo-referencing and field measurements of the orthophotos produced by the GPS and measurement of the work area from two different heights with UAVs. Office work is the part where orthophotos are produced, georeferenced and analyzed with GPS coordinates of control points. The data obtained in the study reduces the rms value when recalibration is performed at a low flight altitude. However, a similar result could not be obtained for 120 meters flight altitude.
Review Paper on an Authentication System using Siamese Convolutional Neural Networks
Authors: Shrey Kekade  , Piyush Morey  , Mayur Rajput  , Sahil Karli  , Priyanka Bendale
Published: March 2023

Due to its distinct advantages, finger vein verification has lately drawn more attention. Focusing on the characteristics of finger vein verification, construct a Siamese structure combining with a modified contrastive loss function for training the above CNN, which effectively improves the network's performance. The experimental findings demonstrate that the lightweight CNN's size shrinks to 1/6th of the pretrained-weights based CNN and that it achieves an equal error rate of 75% in the SDUMLA-HMT dataset, which outperforms cutting-edge techniques and nearly maintains the same performance as CNN that is based on pretrained weights.
Crop Recommendation Using Support Vector Machine (SVM) Classifier
Authors: Prasad Mane  , Abhaysingh Rajpurohit  , Harshal Waghmare  , Ankeeta Ahire  , Prof. Naina Kokate
Published: March 2023

India's primary industry is agriculture. Climate change has a negative effect on the majority of crops. This project will help farmers decide which crop is ideal for their particular plot of land. To recommend the best crop to plant, the SVM algorithm is utilized. The issues we face in regard to weather, temperature, humidity, rainfall, humidity, nitrogen, and phosphorus content in soil are now not being adequately addressed by inventions or solutions. Numerous diverse types of expanding economic growth, notably in the agriculture sector, are occuring in countries like India. Additionally, the process is useful for suggesting crops for suitable terrain. Project will executed using Spyder.
Secure Real Estate Registry System using Blockchain
Authors: Dr. Zainab Mirza  , Mehek Qureshi  , Asad Shaikh  , Parvej Shaikh  , Ismail Khan
Published: March 2023

There are several issues with the current land registry systems that require attention. Firstly, the land registry and transfer process is currently done manually, with only some records and procedures digitized. However, this centralized system is riddled with issues, such as the inability to maintain a complete land history and the lack of a mechanism for detecting record tampering. Addressing these problems through a centralized system is not feasible, but decentralized systems such as Blockchain offer a solution with built-in tamper detection features. In this proposal, we aim to tackle the issues mentioned earlier by implementing a smart contract on the Blockchain network for registering lands. This proposed solution offers various benefits to stakeholders, including enhanced efficiency, transparency, trustworthiness, and integrity throughout the buying and selling process. Additionally, the framework provides a detailed history of the property, ensuring that records remain untampered and reliable. Furthermore, our proposed system is accessible via a Restful external link to traditional property dealing apps, allowing them to extract real-time information on the property, such as its dimensions, location, and price. Ultimately, our solution aims to instill confidence in conducting real estate transactions online
Mechanical Study of Aluminium -Silicon Carbide -Tungsten Carbide Hybrid Composite Synthesized Through Powder Metallurgy Technique
Authors: A. Jagan Mohana Rao  , A Vivek  , A. Raja Sri Charan  , B. Srikar Babu  , B. Durga Prasad  , B. Dinesh
Published: March 2023

In this study, powder metallurgy is used to create hybrid metal matrix alloys made of aluminium-silicon carbide -tungsten carbide. Aluminium metal matrix composites are now vastly used in automobile industry due to superior qualities, such as improved corrosion protection, high ductility, and strength to weight ratio is also high too. With individual silicon carbide reinforcement, weight percentages of 5%, 10%, 15% and 20% of composite samples are created using the powder metallurgy method. The manufactured composite samples' physical and mechanical characteristics were examined. By using two analysis(SEM and XRD), aluminium, siliconcarbide, and tungsten carbide are found. Aluminium -10%Silicon Carbide -10%Tungsten Carbide reinforcement was determined to have a higher ultimate tensile strength (UTS) of 263 MPa as well as yield strength (YS) of 202 MPa for composite. Aluminium -10%Silicon Carbide -15 %Tungsten Carbideand Aluminium -10%Silicon Carbide -20%Tungsten Carbide reinforcement showed that the intermetallic specimenis formed(eg: Al2Cu), which causes a drop in the UTS and YS of manufactured samples. Hybrid composites made of Aluminium, silicon carbide10%, and 10% WC had the greatest combination of mechanical properties. Aluminium, silicon carbide, and WC particles can be seen in the XRD images. Aluminium-silicon carbide 10%-15% WC and aluminium-silicon carbide 10%-20% WC were found to have intermetallic phases present as well. SEM as well as EDS mapping were verified, reinforcements for the 15% and 20% WC reinforcements were distributed uniformly and formed into agglomerations. In comparison to monolithic aluminium, the results revealed that the aluminium-silicon carbide 10%- 10% WC has superior mechanical properties.
Wi-Fi Operated Voice Controlled Home Automation System
Authors: Prof. Y. D. Shahakar  , Manesh Rathod  , Gagan Kurhekar  , Parth Ingle  , Sayali Kalbande  , Damini Changole  , Samiksha Chandel
Published: March 2023

Home automation is a modern technology that helps to enjoy comfortable living conditions inside the home. With home automation, data can be instantly collected and passed between devices and analyzed simultaneously. By connecting the home appliances with the internet, they can be easily accessed from anywhere. In the home automation system, settings are feasible through smartphones or other remote-control devices. This paper gives the design and implementation of a new voice- controlled home automation system that uses Google Assistant for giving user’s voice commands as input. It is a low cost and flexible home automation and monitoring system. It enables the user to use a home automation system based on the Internet of Things (IoT). Home appliances like fans and lights can be controlled. The fundamental purpose of this project is to control electronic appliances based on the situational demands of the user.
Depression Detection using AI, ML and NLP
Authors: Ruchita Chavan  , Mrunal Gosavi  , Maithili Baviskar  , N Parth Goyal
Published: March 2023

Depression is a serious mental illness that can be debilitating. It can interfere with daily activities and cause feelings of sadness, hopelessness, and despair. It is a mental health condition that can range in severity from mild to severe. The severity of depression can be assessed based on the number, intensity, and duration of symptoms, as well as their impact on an individual's daily functioning. Mild depression typically involves symptoms such as feeling sad, low energy, and a lack of motivation. These symptoms may not significantly interfere with an individual's ability to function in their daily life, and they may still be able to maintain their social and occupational obligations. Moderate depression involves more severe and persistent symptoms, such as a sense of hopelessness, persistent feelings of sadness, and difficulty concentrating or making decisions. These symptoms may make it challenging to fulfill daily responsibilities, and may result in social isolation or problems at work or school. Severe depression involves symptoms that significantly impair an individual's ability to function in their daily life, such as suicidal thoughts, complete loss of interest in activities, and difficulty with basic tasks such as personal hygiene or eating. Severe depression is a medical emergency and requires immediate professional intervention to prevent harm to oneself or others
Comparative Study of Half Cut Solar Cell and Bifacial Solar Cell with Standard Solar Cell
Authors: Ujwal Daware  , Darshan Alone  , Gaurav Shende  , Saurabh Deshbhratar  , Sanket Hajare  , Mrs. Shital S. Kewte  , Mr. Shashikant.G. Kewte
Published: March 2023

The main purpose of this thesis is to make comparative study of half cut solar cell and bifacial solar cell with standard solar cell. The main procedure of this thesis was divided into three parts. The first part presents the detailed explanation about the solar cell. The second part shows the information about half cut solar cell . The third part shows the information about bifacial solar cell. This part has included a carefully study in order to choose the most correctly and the financially modules and inverters for the systems. The last two part shows the comparative study of the different PV systems. This part has presented the necessary number of modules and inverters, the total necessary area and the economic analysis for each system. The simulation of the solar cell was done by the software MATLAB/SIMULINK. After the analysis of the results of the different solar cell, it was possible to see which cell technology will be preferable for this system.
Effectiveness of Ultrasound-guided versus Anatomical Landmark-guided Genicular Nerve Block to Treat Chronic Knee Osteoarthritis: A Retrospective Cohort Study
Authors: Singh Sarbhjit , Singh Sarbhan , Nachimuthu Maniventhan , Kassim Ahmad Fauzey , Bhullar Avreena Kaur , Veerakumaran Rajkumar , Kol Goh Ni , Roslan Nurul Azreen Mohd
Published: March 2023

Objectives: There is limited data on the relative effectiveness of different techniques used for administering genicular nerve block (GNB) for pain management of chronic knee osteoarthritis (OA) in the Malaysian population. This study aims to determine and compare the effectiveness of GNB administered using two pain management techniques—anatomical landmark-guided (ALG) and ultrasound-guided (USG)—for chronic knee OA in this population. Methods: This retrospective cohort study included 40 patients with chronic knee OA who received GNB, 20 of whom underwent treatment with the USG technique and the other 20 with the ALG technique. Pain, stiffness, and functional limitation scores were assessed using the Western Ontario and McMaster Universities Osteoarthritis Index Questionnaire (WOMAC) and Numeric Rating Scale (NRS-11) at baseline and post-treatment day one, three weeks, and six weeks. Results: Both groups reported a significant reduction in WOMAC and NRS-11 scores as per their feedback on day one, three weeks, and six weeks post-treatment. Greater reductions in WOMAC and NRS-11 scores were reported by patients who received GNB via USG than by ALG technique, the difference achieving statistical significance at six weeks after treatment (p =0.026). Conclusions: GNB administration using USG and ALG techniques are both effective in significantly reducing pain, stiffness, and functional limitation in patients suffering from chronic knee OA. Among the two techniques, USG appears to be more effective. Nevertheless, GNB guided by ALG continues to be a viable treatment modality, especially in healthcare settings with limited to no USG facilities.
PARP9 knockdown confers protection against chemoresistance and immune escape of breast cancer cells by blocking the PI3K/AKT pathway
Authors: Hong Tao , Dong Dingxiang , Li Jun , Wang Lin
Published: March 2023

Introduction

This study probes the mechanism of the PARP9/PI3K/AKT/PD-L1 axis in the chemoresistance and immune escape of breast cancer cells.

Material and methods

The expression of related genes was detected in MCF-7/FUL cells. After MCF-7/FUL cells were treated with sh-PARP9 and/or the PI3K/AKT pathway activator, drug resistance, proliferation, migration, invasion, and apoptosis were measured. Afterward, MCF-7/FUL cells were co-cultured with CD8+ T cells to examine the positive rate and density of MCF-7/FUL cells, the percentage and apoptosis of CD8+ T cells, and the expression of immune-related factors in cell supernatants. Nude mice were subcutaneously injected with sh-PARP9-transfected MCF-7/FUL cells for in vivo validation.

Results

PARP9 was highly expressed in MCF-7/FUL cells. Sh-PARP9 transfection suppressed cell migration, proliferation, and invasion while accelerating apoptosis in MCF-7/FUL cells, accompanied by downregulated PD-L1, p-PI3K, and p-AKT expression, and reduced IC50 and FUL resistance. After co-culture of MCF-7/FUL cells with CD8+ T cells, the percentage of CD8+ T cells, the expression of immune-related factors in supernatants, and the positive rate of MCF-7/FUL cells increased, while the apoptosis of CD8+ T cells and the density of adherent MCF-7/FUL cells were diminished. These trends were negated by further activating the PI3K/AKT pathway. PARP9 knockdown suppressed xenograft growth, decreased p-PI3K, p-AKT, PD-L1, and cyclin D1 expression, and augmented p-Cdc2 and cleaved caspase 3 levels in nude mice.

Conclusions

PARP9 knockdown blocked the PI3K/AKT pathway to downregulate PD-L1, thus depressing chemoresistance and immune escape in breast cancer.
Effects of mind-body therapies in knee osteoarthritis: a systematic review and network meta-analysis
Authors: Ma Yanfei , Wang Chunyan , Peng Qiyan , Hou Ailin , Li Yeping , Hu Rong , Yin Yang
Published: March 2023

Introduction

Knee osteoarthritis (KOA) is a frequent degenerative condition. Patients with KOA have employed mind-body therapies frequently, and their efficacy has been established. The main purpose of our study is to compare the effects of different mind-body therapies on patients with KOA.

Material and methods

Only randomized controlled trials (RCTs) were gathered through searches in the Cochrane Library, PubMed, EBSCO, Web of Science, Medline, and Embase to investigate the effects of various mind-body therapies on effect in KOA patients. The Cochrane bias risk assessment tool was used to assess the methodological quality of the included studies, and the data analysis program was then used to analyze the data in accordance.

Results

The study used an overall sample size of 859 from a total of 17 RCTs. In addition, a total of 13 different mind-body therapies were included in our study. According to the network meta-findings, analysis's patients' scores on the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) can be significantly improved by Baduanjin (SUCRA:98.3%), the Time Up and Go (TUG) Test can be significantly decreased by balance training (SUCRA:99.4%), the 36-Item Short Form Health Survey questionnaire's mental health component can be significantly improved by MBSR (SUCRA:87.9%), and balance training can significantly improve patients’ physical health component of SF-36 (SUCRA:90.3%).

Conclusions

According to the Network's Ranking Plot, Bajuanjin or Balance Training and MBSR can offer patients with KOA higher benefits for motor function or quality of life than other mind-body therapies. The medical staff can choose different mind-body therapies according to the patient's actual condition.
Hyponatremia in patients with arterial hypertension –pathophysiology and management
Authors: Adamczak Marcin , Surma Stanisław , Więcek Andrzej
Published: March 2023

In physiological conditions sodium concentration in plasma oscillates between 135-145 mmol/l. The kidneys play most important role in the regulation of sodium homeostasis. In recent years, a significant role of glycosaminoglycans, localized mainly in the subcutaneous tissue and the role of glycocalyx on the surface of vascular endothelial cells, was documented in the regulation of sodium metabolism. Hyponatremia is defined by a plasma sodium concentration lower than 135 mmol/l. Hyponatremia significantly worsens the prognosis of patients with different chronic diseases. In patients with arterial hypertension, the risk of hyponatremia is 1.5 times higher than in the general population. The symptoms of hyponatremia are caused mainly by the swelling of cells in the central nervous system. Treatment of hyponatremia depends on the degree and type of hyponatremia as well as presence of clinical symptoms. Too rapid correction of hyponatremia might result in a potentially fatal osmotic demyelinating syndrome.
Galectin-3 regulates skeletal muscle loss via TGFβ1-Smad2/3 signaling activation in mice
Authors: Ji Xueying , Jiang Xin , Yang Fan , Yu Jiaming , Xue Mengjuan , Bao Zhijun
Published: March 2023

Introduction

Endogenous glucocorticoids (GCs) played a pivotal role in the pathogenesis of skeletal muscle loss. However, to date, the underlying molecular mechanisms underlying are not yet fully understood. Galectin-3 (Gal-3) is a member of a beta-galactoside-binding animal lectins, consistently associated with inflammation and fibrosis in the pathogenesis of various disease states. The present study aimed to explore the role of Gal-3 in GC-induced skeletal muscle loss.

Material and methods

Myogenic differentiation capacity was detected after in vitro Gal-3 knockdown (KD) or in vivo administration of Gal-3 inhibitor. The activation of transforming growth factor type beta 1 (TGFβ1) and Smad2/3 signaling pathways was determined by western blot, co-immunoprecipitation, and immunofluorescence.

Results

Gal-3 was up-regulated during dexamethasone (Dex) administration in mice. In the established GC-induced muscle loss model, Gal-3 inhibition recovered grip strength and muscle mass. In vitro, Gal-3 KD promoted the myogenic differentiation capacity of C2C12 myoblasts, and prevented the reduction of fully differentiated myotubes. Gal-3 results in overexpression of TGFβ1 and TGFβR-I, which affects Smad2, 3 phosphorylation and subsequently mediates skeletal muscle reduction by activating the Smad2/3 signaling pathways.

Conclusions

The present study demonstrated that Dex elevated Gal-3 levels in skeletal muscle. Gal-3 facilitates the activation of TGFβ1-Smad2/3 signaling pathways in myoblasts, and contributes to myogenesis inhibition and skeletal muscle loss. This study raises awareness about the follow-up of patients receiving GC therapy. Further, inhibition of Gal-3 provides a possible therapeutic strategy for skeletal muscle loss.
INCREASING HEALTH PROFESSIONALS’ ABILITY TO RECOGNIZE, DIAGNOSE, AND INTERVENE IN AUTISM SPECTRUM DISORDER CASES IN AFRICA: EXAMPLES FROM SPECIFIC DEVELOPMENTAL STAGES- A LONGITUDINAL CASE STUDY.
Authors:   , Wannenburg Nicola , van Niekerk Roelf
Published: March 2023

Background: As awareness surrounding autism spectrum disorder (ASD) in Africa has increased, the high rate of non-verbal autism on the continent has come to the fore. Late diagnosis and access to viable interventions are continued concerns. Due to the greater focus on communicable diseases in healthcare curriculums, healthcare professionals frequently do not possess the required knowledge and experience to diagnose cases of neurodevelopmental disorders. Nurses are often the first healthcare professionals to encounter autistic individuals or their families because of being the first professionals whose advice is sought about worrisome symptoms, either by high-functioning individuals with autism or by a worried parent of a newborn or toddler. Methods: A narrative review of healthcare professionals’ knowledge of ASD in Africa provided context for the research and highlighted areas needing focus. A qualitative mixed-method case study was used to highlight symptoms and potential behaviors of autism that healthcare practitioners may face in practice. Findings: A lack of focus on neurodevelopmental disorders in healthcare curriculums has led to an inability to recognize, diagnose, and intervene in ASD cases across Africa, which places a greater burden on families, especially in low-resource settings. Nurses are central in both clinics and communities. Nurses’ ability to discern neurodevelopmental and autistic behavior from typical childhood development is crucial to timely diagnosis and intervention as well as accurate treatment of presenting communicable diseases or co-morbidities. Increasing health professionals’ awareness and understanding of autism spectrum disorder should aid in the reduction of undiagnosed and untreated cases. Conclusions: Healthcare professionals’ ability to diagnose developmental disorders at a younger age, may increase the chances of intervention and autonomy in children with neurodevelopmental disorders and support for families. Recommendation: In order to facilitate early diagnoses and intervention of neurodevelopmental disorders, greater emphasis needs to be placed on non-communicable diseases in health care curriculums.
AN EVALUATION OF THE CLINIC RADIOLOGICAL EFFECTS OF SINGLE-VERSUS DOUBLE-BUNDLE ARTHROSCOPIC ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION.
Authors:   , Chandra Dey Paresh
Published: March 2023

Introduction:  The most common reconstructive procedure for the knee is anterior cruciate ligament (ACL) reconstruction. This research aimed to compare the clinical and radiological outcomes of arthroscopic ACL replacements using single- and double-bundles. Method:  80 patients with isolated ACL injuries had surgery between July 2020 and July 2021, with groups for the single bundle (SB) and double-bundle (DB) reconstructions each consisting of 40 individuals. The GNRB arthrometer, the International Knee Documentation Committee, and the Lysholm scale were used to evaluate the results. The lateral pivot-shift test was used to evaluate rotational stability. To compare the repaired ACL graft orientation, postoperative magnetic resonance imaging (MRI) was done. Using a paired t-test, preoperative values, and values were compared and P <0.04 was significant. Result:  The average follow-up was 18.2 months for the DB group and 14.8 months for the SB group. The mean Lysholm score was 94.12±2.66 in the SB group and 93.12±3.30 in the DB group at the time of the final follow-up (P value = 0.201, statistically insignificant). All of the patients, in both groups, were in grade A or B. The mean differential anterior tibial translation in the SB group was 1.44 ± 0.5 mm and in the DB group, it was 1.16 ± 0.7 mm (P = 0.104, NS). In the DB group, all of the pivot shift tests were negative, whereas, in the SB group, three patients showed positive results. According to an MRI of surgically repaired knees, both groups' mean sagittal and mean coronal ACL graft-tibial angles were equivalent (P value > 0.04, NS). Conclusion: At an average of 15 months of follow-up, there was no statistically significant difference between the single-bundle and double-bundle ACL repair groups in terms of knee stability, knee ratings, subjective assessments, or MRI examination of graft inclination angles.
Variabilidad del ritmo cardiaco en menores de 18 años con parálisis cerebral y su relación con la motricidad gruesa: una revisión sistemática
Authors: QUEVEDO CEPEDA RAFAEL , SMITH PLAZA RAÚL , NAHUELHUAL CARES PAULA
Published: March 2023

Introducción: La Parálisis Cerebral (PC) es la principal causa de defi­ciencia motriz en la población infanto-juvenil. Su rehabilitación requiere de sistemas de medición no invasivos, costo-efectivos y de fácil aplicación. La variabilidad del ritmo cardiaco (VRC) cumple estos requisitos, pero aún faltan parámetros de referencia en menores de 18 años con PC. El objetivo es escribir la VRC en menores de 18 años con PC y su relación con la motricidad gruesa, según el Gross Motor Function Classification System (GMCFS). Materiales (o pacientes) y Métodos: Revisión sistemática. Se buscó en 11 bases de datos y referencias de estudios elegibles que incluyeron diseños observacionales, experimentales y cuasi-experimentales, población menor de 18 años con PC y clasificados con GMFCS. La VRC se evaluó en reposo utilizando análisis de dominio de tiempo y frecuencia. El riesgo de sesgo se evaluó con Robins-I. Resultados: Se identificaron 264 artículos. Siete cumplieron con los criterios de inclusión, con un total de 242 pacientes con edades entre 4 y 14 años. Los informes de VRC se realizaron a través de los dominios de tiempo (SDNN y rMSSD) y/o frecuencia (HF, LF, HF y LF/HF). Conclusiones: Existe evidencia limitada sobre el análisis de los diferentes dominios de la VRC en menores de 18 años con CP. Los hallazgos son contradictorios con respecto a la relación entre VRC y GMFCS. Aún se requiere un mayor número de estudios, mayo­res tamaños muestrales y un mejor control de las variables de confusión para generar relaciones y parámetros de referencia según GMFCS.
Efecto del uso de órtesis tóraco lumbo sacro correctivo en la evolución de la escoliosis en pacientes con parálisis cerebral GMFCS IV-V. Estudio de cohortes retrospectivas dinámicas
Authors: REYES MARTÍNEZ OSCAR ROBERTO , SOTO VIDELA PAULA DEL CARMEN
Published: March 2023

Introducción: La escoliosis es una deformidad frecuente en niños con parálisis cerebral (PC), es progresiva y afecta negativamente la capacidad funcional. A nivel internacional, curvas escolióticas sobre 45° grados reciben cirugía correctiva como tratamiento para mantener la curva escoliótica y evitar su progresión; a nivel local se utiliza un tratamiento conservador con ortesis toraco-lumbo sacra (TLSO). Al respecto, el presente estudio buscó comparar la evolución de la escoliosis en pacientes con tratamiento de TLSO durante 12 meses con la historia natural de la escoliosis. Materiales (o pacientes) y Métodos: Estudio de dos cohortes dinámicas de pacientes con diagnóstico de PC, escoliosis mayor a 20° e indicación de TLSO entre enero de 2017 y diciem­bre de 2019 en el Instituto Teletón (IT) Santiago. Durante un año se evaluó la curva escoliótica mediante método Cobb y tiempo mediano transcurrido por presencia de evento adverso (cambio de TLSO). Resultados: Se identificaron diferencias, estadísticamente significativas, en la curva escoliótica entre la medición basal y el primer control, y entre el primer control y el último. No hubo variables demográficas o clínicas asociadas, significativamente a las variaciones de la curva escoliótica. Se identificó una diferencia importante entre las curvas de sobrevivencia de quienes presentaron un evento adverso y aquellos que no. Conclusiones: El TLSO detuvo la progresión de la curva escoliótica tras 12 meses de uso. La falta de casos comparables impidió con­trastar los resultados obtenidos con la historia natural de la escoliosis descrita en el antecedente teórico disponible.
Efectividad de Armeo®Spring Pediatric en niños con parálisis braquial obstétrica Narakas I. Ensayo clínico, controlado, aleatorio de grupos paralelos
Authors: STUARDO DOMÍNGUEZ LESLIE , MARÍN VICUÑA VERÓNICA , BENAVENTE PIZARRO AMPARO
Published: March 2023

Introducción: La parálisis braquial obstétrica (PBO) es una parálisis flá- cida del brazo asociada a eventos adversos durante el parto y que lesiona los nervios de las raíces cervicales C5 a T1. Convencionalmente, su rehabilitación es mediante intervenciones kinésicas y de terapia ocupacional (TC), o bien con una herramienta innovadora: asistencia robótica y realidad virtual llamada Armeo®Spring Pediatric (Armeo). Entonces, el objetivo de investigación fue comparar la efectividad del Armeo con la TC en la función de la extremidad superior. Materiales (o pacientes) y Métodos: Ensayo clínico controlado, paralelo, aleatorizado con enmascaramiento simple. Participaron 10 usuarios/ as activos entre 5 y 8 años de edad con PBO, Narakas I, del Instituto Teletón Concepción. Se realizaron 15 entrenamientos de 45 minutos cada uno, 3 veces por semana, evaluando según escala de Mallet y rangos articulares de movi­miento pasivo (ROM) post intervención, a 3 y 6 meses. Resultados: Hubo diferencias estadísticas significativas en la escala Mallet: Rotación externa a 3 y 6 meses, Mano-cabeza post intervención y en el puntaje Total post in­tervención, a 3 y 6 meses. Según la evaluación ROM, dichas diferencias se registraron en Abducción a 3 y 6 meses. En todos estos indicadores la TC tuvo mejores efectos y más perdurables. Conclusiones: Los resultados obtenidos con el Armeo requieren de un ambiente especializado para perdurar en el tiempo, mientras que los obtenidos con la TC perduran más, dada la mayor variedad de experiencias sensoriomotoras que ésta ofrece y por la posibilidad de practicar cotidianamente lo aprendido en los entrenamientos.
Congreso ORITEL 2023. “Puedes saber si una persona es inteligente por sus respuestas. Puedes saber si una persona es sabia por sus preguntas”.
Authors: García Palomer Daniela
Published: March 2023

N/A
Sexualidade e Bem‐Estar nas Pessoas com Deficiência Intelectual Moderada: Estudo Tranversal
Authors: Pinto Joana , Morgado Bruno
Published: March 2023

Introdução: A deficiência intelectual (DI) tem sido negligenciada ao longo dos tempos, ganhando notoriedade nos últimos anos através de estudos que visam melhorar a qualidade de vida destas pessoas. A sexualidade é um dospontos que mereceu atenção, pela falta de conhecimentos existente, pelas poucas experiências positivas e sentimentos negativos em relação à sexualidade das pessoas com DI. A grande expansão deste tema ocorreu quando surgiram casos de VIH e frequentes abusos sexuais, nestas pessoas. Pretendemos com este estudo identificar as associações entre indicadores de sexualidade e bem‐estar das pessoas com DI, bem como avaliar os níveis de conhecimento, experiência, necessidades e atitudes relacionadas à sexualidade, e a vulnerabilidade ao abuso sexual em situações de coação sexual.
Material e Métodos: O estudo envolveu 86 pessoas com DI moderada (49 homens e 37 mulheres), com idade igual ou superior a 18 anos, não institucionalizadas, da zona Norte de Portugal. Os instrumentos utilizados foram o Sexuality Knowledge, Experience and Needs Scale for People with Intellectual Disability (SexKen‐ID), que avalia questões relacionadas com a sexualidade, e o Personal Wellbeing Index – Intellectual Disability (PWI‐ID), que avalia o bem‐ ‐estar pessoal.
Resultados: Os resultados sugerem que as pessoas com DI apresentam níveis baixos de conhecimento, de experiência, necessidades elevadas e sentimentos negativos face à sexualidade. No que diz respeito a situações de abuso sexual, indicaram uma baixa capacidade de responder de forma assertiva. Não foram encontradas correlações estatisticamente significativas entre a sexualidade e o bem‐estar das pessoas com DI.
Conclusão: A falta de conhecimentos em sexualidade deixa as pessoas com DI mais vulneráveis, motivo pelo qual é crucial implementar programas de promoção do bem‐estar e educação sexual, a fim de normalizar a expressão da sexualidade e aprimorar a capacidade para gerir sentimentos e lidar com situações de abuso sexual.
Topical issues of economic development of production activities of the Penal system of the Russian Federation
Authors: Загарских В.В. , Утёмов А.С.
Published: March 2023

Одной из приоритетных задач, поставленных перед уголовно-исполнительной системой, является развитие производственного сектора. В данной статье выделены актуальные вопросы, связанные с развитием и эффективным управлением производственной деятельности в учреждениях уголовно-исполнительной системы Российской Федерации: это вопросы строительства производственных и вспомогательных помещений при наличии свободных земельных участков на охраняемой территории и за ее пределами в целях увеличения производственной мощности учреждения, а также дополнительного привлечения осужденных к труду; формирования оперативной информации на базе программных продуктов бухгалтерского учета, объединяющей данные различных технологических процессов производства, и оценка финансовых результатов по фактическим и кассовым расходам, связанная с определением дальнейшего использования объема прибыли, направления денежных потоков, объемов инвестиций по направлениям приносящей доход деятельности учреждений уголовно-исполнительной системы Российской Федерации.

One of the priority tasks set for the penal system is the development of the manufacturing sector. This article highlights topical issues related to the development and effective management of production activities in the institutions of the penal system of the Russian Federation: these are the issues of construction of production and auxiliary premises in the presence of free land plots in a protected area and beyond in order to increase the production capacity of the institution, as well as additional involvement of convicts in labor; the formation of operational information based on accounting software products that combines data from various technological processes of production, and the assessment of financial results in terms of actual and cash costs associated with determining the further use of profits, the direction of cash flows, the volume of investments in the areas of income-generating activities of penal institutions systems of the Russian Federation.
Article preparation methodology
Authors: Антипов А.Н.
Published: March 2023

Цель данной работы заключается в том, чтобы, акцентируя внимание на типичных ошибках, допускаемых при подготовке научных статей, предложить некий алгоритм, который позволит их минимизировать и тем самым повысить качество научной продукции. Осуществлен анализ качества научных статей, рецензентом которых выступал автор, на предмет их структурированности, логичности, системности изложения материала, проработанности и глубины проведенных исследований, наличия научной новизны, обоснованности формулируемых выводов и предложений. В результате представлен алгоритм, который позволит избежать большинства допускаемых ошибок, расширить общетеоретические знания молодых авторов, усилить взаимосвязь теории и практики, будет способствовать повышению качества научных статей, расширит круг потенциальных читателей.

The purpose of this work is to focus on the typical mistakes made in the preparation of scientific articles, to propose an algorithm that will minimize them and thereby improve the quality of scientific products. The analysis of the quality of scientific articles reviewed by the author was carried out in terms of their structure, consistency, systematic presentation of the material, the elaboration and depth of the research, the presence of scientific novelty, the validity of the formulated conclusions and proposals. As a result, an algorithm is presented that will help to avoid most of the mistakes made, expand the general theoretical knowledge of young authors, strengthen the relationship between theory and practice, improve the quality of scientific articles, and expand the circle of potential readers.
On the results of the work of the International scientific and practical conference on the problems of the execution of criminal penalties «The Penal System at the Present stage, with respect to the implementation of the Concept for the development of the penal system of the Russian Federation for the period up to 2030»
Authors: АКЧУРИН А.В. , ПАРШКОВ А.В. , ЧУДАКОВА С.Н.
Published: March 2023

В ноябре 2022 года в Академии ФСИН России состоялась Международная научно-прак- тическая конференция «Уголовно-исполнительная система на современном этапе с учетом реализации Концепции развития уголовно-исполнительной системы Российской Федерации на период до 2030 года». Ее проведение было направлено на развитие и совершенствование научно-исследовательской и практи- ческой деятельности в сфере исполнения уголовных наказаний, изучение состояния мирового пенитен- циарного опыта и поиск перспективных форм и методов работы с осужденными, содействие развитию и углублению межгосударственного пенитенциарного сотрудничества.

In November 2022, the Academy of the Federal Penitentiary Service of Russia hosted the International Scientific and Practical Conference «The Penal System at the Present Stage, with respect to Account the Implementation of the Concept for the Development of the Penal System of the Russian Federation for the period up to 2030». It was aimed at developing and improving the research and practical activities in the field of execution of criminal sentences, studying the state of world penitentiary experience and searching for promising forms and methods of working with convicts, promoting the development and deepening of interstate penitentiary cooperation.
Süper Emici Polimer Katkılı Harçların Isıl İşlem ile Hava Küründe Mekanik Özellikleri
Authors: DİLBAS Hasan , BİRDAL Furkan
Published: March 2023

Günümüzde süper emici polimerlerin kullanım alanları gittikçe yaygınlaşmaktadır. Bu polimerlerin beton karışımı içerisindeki davranışları ve betonun mekanik özellikleri üzerindeki etkisi araştırılmaktadır. Bununla birlikte, süper emici polimerlerin harç ve çimento pastası fazları üzerindeki etkileri de önemli bir araştırma konusudur. Bu makale kapsamında, süper emici polimer katkılı harçların farklı kür şartları altındaki mekanik davranışları deneysel olarak incelenmiştir. Deneylerde, 18 adet süper emici polimer katkılı ve 3 adet katkısız harç fazında 15x15x15 cm boyutlu küp numuneler üretilmiştir. Süper emici polimer katkılı harçlarda, polimer katkı oranı literatürden optimum %0,3 olarak belirlenmiştir. Deney numuneleri süper emici polimer katkılı, ısıl işlem uygulanmadan 3-5-10 gün hava küründe ve 1 gün ısıl işlem uygulaması ardından 2-4-9 gün hava kürü koşullarına göre sınıflandırılmıştır. Her bir deney numunesi için eksenel basınç dayanımı testi gerçekleştirilmiştir. Deneysel sonuçlardan, numunelerin gerilme-şekil değiştirme eğrileri elde edilmiştir. Bu eğrilerin karşılaştırılması neticesinde, süper emici polimer katkılı harçların mekanik performansında (eksenel basınç dayanımı, elastisite modülü ve enerji tüketme kapasitesi) en efektif ısıl işlem ve hava kürü kombinasyonu belirlenmiştir. Çalışmamız ile, süper emici polimer katkılı beton, bu betondan üretilmiş yapı taşıyıcı sistem elemanı (kolon, kiriş, perde, döşeme, vb.) davranışları ve süper emici polimer katkılı betonun teorik olarak modellenmesi bilimsel araştırmalarına katkı sunulması hedeflenmiştir.
Deneysel Mimarlık Üretiminde İnsansız Hava Araçlarının Rolleri
Authors: İMERT Hakan
Published: March 2023

Teknolojinin hızla gelişmesine paralel olarak deneysel mimarlık üzerine yapılan çalışmalar mimarlıkta üretim şekillerinin çeşitlendirilmesinde önemli roller oynamaktadır. Üretim ve hizmet süreçlerinde robot kullanımı için artan talepler, deneysel mimarlık üzerine çalışan uzmanların dikkatini çekmektedir. Bu sayede insansız hava araçları da üretim süreçlerinde önemli bir özne haline gelmektedir. Bu çalışmanın amacı, insansız hava araçlarının rollerini mimarlık üretimine getirdiği yenilikçi çözümler üzerinden keşfetmeye dayanmaktadır. Araştırma oluşturulan kavramsal çerçeve paralelinde deneysel mimarlıkta insansız hava araçları ile üretime dair durum çalışmalarına odaklanmaktadır. Bu çalışmalara ait nesnel veriler SWOT analizi yöntemi ile sundukları güçlü yönler, zayıf yönler, fırsatlar ve tehditler üzerinden değerlendirilmektedir. Yapılan incelemeler neticesinde, durum çalışmaları içerisinde benzer teknoloji ile üretilmelerine rağmen farklı güçlü ve zayıf yönlerin ortaya çıktığı görülmektedir. Ancak, ortaya çıkan fırsatlar ve tehditlerin durum çalışmaları arasında benzerlikleri de söz konusudur. Seçili örnekler ile sınırlandırılan çalışma sonucunda, insansız hava araçları ile hibrit üretimin dünyada mevcut mimarlık anlayışlarını değiştirecek bir etkiye sahip olduğu anlaşılmaktadır.
Yeşil Çatı Uygulamalarının Yaygınlaştırılması: Organik Tarıma Elverişli Yeşil Çatı
Authors: ÖZER Gonca , YETKİN Elif Gizem
Published: March 2023

Kentlerde yeşil alanların yok olması kentsel ısı adası, kentsel çevrelerde kirlilik gibi birçok sorunu da beraberinde getirmektedir. Bu sorunlar doğrultusunda insanların kentlerde yeşil alan ihtiyacı her geçen gün artmaktadır. Bu sorunlara çözüm olarak yeşil çatı sistemleri düşünülebilmektedir. Yeşil çatılar, mekanların üst örtülerindeki alanların yeşil doku ile değerlendirilebileceği alanlara dönüştürülerek oluşturulmaktadır. Bu çatı sistemlerinin yaygınlaştırılması ve yeni yorumlar katılması kentlerde meydana gelen pek çok soruna çözüm üretmek noktasında fayda sağlayacaktır. Yeşil çatılar organik ürün yetiştirmeye elverişli alanlar olarak değerlendirilirse daha etkili kullanım olanağı oluşturulabilecektir. Bu çalışmada konut kullanıcılarının yeşil çatılar ve organik ürün yetiştirmeye elverişli yeşil çatılar ile ilgili görüşleri alınarak insanların kentlerde bu alanlara duydukları eksiklik ve yeşil çatılara bakış açıları sorgulanmıştır. Konut kullanıcılarının organik yeşil çatı ile ilgili görüşleri alınarak bu uygulamaların hayatlarını nasıl etkileyeceği sorgulanmıştır. Çalışma kapsamında 210 kişiye anket uygulanmıştır. Anket sonuçları grafiklerle değerlendirilerek yorumlanmıştır. Çalışmada kullanıcıların yeşil çatılara bakış açıları değerlendirilerek kullanıcıların bu alanlara ihtiyaç duyduğu veriler ortaya konmuştur. Elde edilen sonuçlara göre insanlar kentlerde organik yeşil çatılara ihtiyaç duymaktadır ve tasarlanacak yapıların üst örtülerinin organik yeşil çatı olarak planlanmasının gerekliliği açıkça ortaya konmaktadır.
Perkembangan Iman Orang Muda Katolik di Perkotaan
Authors: Sinaga Adelbred , Firmanto Antonius Denny
Published: March 2023

Orang muda adalah aset negara dan Gereja yang sangat penting. Orang muda tidak dapat dipisahkan dari usaha mencapai tujuan bangsa dan negara pun gereja. Mereka memiliki pengetahuan yang baru, tingkat kreativitas yang tinggi, keunikan dan kekhususan yang perlu dikembangkan. Dengan demikian, kehadiran mereka pun dapat membawa berkat bagi sesama dan perkembangan bagi gereja. Oleh karena itu, peran orang muda tidak boleh diabaikan. Penelitian ini berangkat dari sebuah pengamatan penulis di paroki asalnya. Penulis menemukan kurangnya keaktifan Orang Muda Katolik di paroki tersebut.Orang Muda Katolik perlu pendampingan dari Gereja. OrangMuda Katolik yang adalah masa kini dan masa depan Gerejaperlu didampingi dan dipersiapkan sejak saat ini. Penelitian inibertujuan untuk memberi wawasan tentang perkembangan imanOrang Muda Katolik di tengah perkembangan teknologi (internet)dan menumbuhkan minat Orang Muda Katolik dalam kehidupanmenggereja dan keikutsertaan dalam pelayanan di gereja.Penelitian ini menggunakan metode kuantitatif untuk mengetahuibagaimana keaktifan orang muda dalam kegiatan menggereja,dan juga metode studi pustaka. Penulis membuat pertanyanpertanyaandalam google form dan kemudian dibagikan kepada103 orang responden. Penulis juga mencari referensi-referensiyang cocok dengan ide-ide penulis. Hal yang ingin dicapai olehpenulisan ini adalah mengetahui tingkat keaktifan Orang MudaKatolik dalam kehidupan menggereja, dan bagaimana usahaGereja dalam mendampingi Orang Muda Katolik.