bluuebunny/crossref_metadata_2025 huggingface dataset:
Pitavastatin Combined with Ezetimibe Treatment was an Effective Approach to Non-IRA Lesion of ST-segment Elevation Myocardial Infarction Patients with Primary Percutaneous Coronary Intervention
Authors: Zhao Bo , Li Guang-Ping , Peng Jian-Jun , Ren Li-Hui , Lei Li-Cheng , Ye Hui-Ming , Wang Zuo-Yan , Zhao Sheng
Published: June 2020

Objective:

ST-Segment Elevation Myocardial Infarction (STEMI) patients with the multivessel
disease have distinctive plaque characteristics in non-IRA lesions. Intensive statin therapy was
a potential approach to treat STEMI patients with the non-IRA disease. However, there is still poor evidence
about the therapeutic effect. In this study, we have evaluated the detailed therapeutic effect of
statin plus ezetimibe intensive therapy.

Methods:

For STEMI patients with non-IRA disease undergoing primary Percutaneous Coronary Intervention
(PCI), 183 control STEMI patients without non-IRA disease undergoing primary PCI, and
200 STEMI patients with non-IRA disease undergoing primary PCI were introduced into this study.
200 STEMI patients with non-IRA disease undergoing primary PCI were divided into Normal group,
Intensive group, Normal & Combined group, and Intensive & Combined group. The baseline information
for each participant was recorded. Meanwhile, the physiological and biochemical indicators of
each member with different treatments were collected after one-year follow-up.

Results:

For STEMI patients with non-IRA disease undergoing primary PCI, no differences could be
detected in multiple indexes such as OCT examination results, age, stroke, etc. However, diabetes
mellitus, smoking, and coronary Gensini score were different between different groups (P<0.05). After
one year follow-up, cholesterol, low-density lipoprotein, coronary Gensini score, thin-cap fibroatheroma,
length of non-infarcted arterial lesions, non-infarct artery lesion range, myocardial infarction
again, and revascularization again were significantly different between different groups (P<0.05).

Conclusion:

The results mentioned above suggested that pitavastatin combined with ezetimibe was an
effective approach for STEMI patients with non-IRA disease undergoing primary PCI. The results obtained
in this study have provided a novel method for the treatment of STEMI patients with non-IRA
disease undergoing primary PCI.
Fibroblast Growth Factor: Promising Target for Schizophrenia
Authors: Talaei Ali , Farkhondeh Tahereh , Forouzanfar Fatemeh
Published: June 2020

Schizophrenia is one of the most debilitating mental disorders around the world. It is characterized
by neuroanatomical or biochemical changes. The role of the fibroblast growth factors (FGFs)
system in schizophrenia has received considerable attention in recent years. Various changes in the
gene expression and/or level of FGFs have been implicated in the etiology, symptoms and progression
of schizophrenia. For example, studies have substantiated an interaction between FGFs and the signaling
pathway of dopamine receptors. To understand the role of this system in schizophrenia, the databases
of Open Access Journals, Web of Science, PubMed (NLM), LISTA (EBSCO), and Google
Scholar with keywords including fibroblast growth factors, dopamine, schizophrenia, psychosis, along
with neurotrophic were searched. In conclusion, the FGF family represent molecular candidates as
new drug targets and treatment targets for schizophrenia.
Berberine Nanoencapsulation Attenuates Hallmarks of Scoplomine Induced Alzheimer's-Like Disease in Rats
Authors: Saleh Samar R. , Abady Mariam M. , Nofal Mohammed , Yassa Nashwa W. , Abdel-Latif Mohamed S. , Nounou Mohamed Ismail , Ghareeb Doaa A. , Abdel-Monaem Nihad
Published: June 2020

Background:

Berberine (BBR), an isoquinoline alkaloid, acts as a multipotent active
pharmaceutical ingredient to counteract several types of dementia based on its numerous pharmacological
actions including antioxidant, anti-inflammatory, cholesterol-lowering effect, and inhibition
of Aβ production and AChE. However, BBR suffers from poor absorption, bioavailability and
brain drug uptake. The present study is directed for the formulation and characterization of Chitosan
BBR-Nanoparticles (BBR-NPs) as well as the estimation of its neuroprotective effects against scopolamine
induced cognitive impairments.

Methods:

BBR-NPs were formulated using the ionic gelation method, and tripolyphosphate was
chosen as a crosslinker. Nanoparticles size, zeta potential, encapsulation efficiency and releasing
profile were estimated. To investigate the neuroprotective effects, adult fifty-six Wistar male rats
were randomly distributed into three control groups, received saline, polyethylene glycol or Chitosan-
NPs, respectively; induced group, received scopolamine (2 mg/ kg, i.p.) and three treated
groups were orally administrated BBR (50 mg/ kg), BBR- NP (7 mg/ kg) and donepezil (2.25 mg/
kg, as positive control) followed by scopolamine injection after 40 min, daily for 4 weeks. Morris
water maze test, oxidative stress parameters, cholinergic and amyloid-β processing intermediates, as
well as neuroplasticity markers and histopathological examination were assessed.

Results:

Our results showed that BBR- NPs were better than BBR and donepezil as BBR- NPs were
powerful inhibitory ligands towards AChE and Aβ42 formation and significantly down-regulated
Tau, iNOS and BACE gene expression in rats’ hippocampus. BBR-NPs administration, at 1/6 of
BBR therapeutic recommended dose, significantly improved learning and memory function. This
could be accredited to the diminution of oxidative stress and amyloid-β toxicity in addition to the
improvement of the neuroplasticity markers.

Conclusions:

The enhancing effect of BBR- NPs could be related to the enhancing of its bioavailability,
absorption and brain drug uptake, which need more investigation in future work.
Light Alcohol Drinking and the Risk of Cancer Development: A Controversial Relationship
Authors: Caprio Giuseppe G. , Picascia Desiree , Dallio Marcello , Vitiello Pietro P. , Giunta Emilio F. , De Falco Vincenzo , Abenavoli Ludovico , Procopio Anna C. , Famiglietti Vincenzo , Martinelli Erika , Gravina Antonietta G. , Federico Alessandro , Ciardiello Fortunato , Loguercio Carmelina , Ciardiello Davide
Published: June 2020

Background:

In accordance with the scientific literature heavy alcohol consumption
(>50g per day) represents a risk factor for several diseases development, including cancer. However,
the oncogenic role of light alcohol drinking (<12.5g per day) is still unknown.

Objective:

To assess the scientific knowledge about light alcohol consumption and the risk of malignancy
onset.

Methods:

To collect the scientific evidences regarding this topic the keywords “light alcohol drinking”,
“light alcohol consumption” and “cancer”, were used. Papers published during the last 15
years were analyzed, in order to select the most recent evidence. Meta-analyses with well-defined
levels of alcohol intake were included in the present review. Other studies that focused on biochemical,
molecular and genetic aspects, as well as duplicate articles, were excluded.

:

Furthermore, a possible protective role of light alcohol consumption on the development of bladder,
kidney and ovarian cancer and Non Hodgkin Lymphoma was observed.

Results:

Twenty-nine large, meta-analyses were included in this review. Light alcohol drinking
was not associated with an increased risk of cancer occurrence, with the exception of breast and
prostate cancer and melanoma.

Conclusion:

Light alcohol drinking was not associated with the development of several malignancies,
except for a light increase of melanoma, breast cancer in women and prostate cancer in men.
Detection of Streptococcus pneumoniae in Sputum Samples by Real-Time PCR
Authors: Shakib Pegah , Zolfaghari Mohammad R.
Published: June 2020

Background:

Conventional laboratory culture-based methods for diagnosis of Streptococcus
pneumoniae are time-consuming and yield false negative results. Molecular methods including
real-time (RT)-PCR rapid methods and conventional PCR due to higher sensitivity and accuracy
have replaced traditional culture assay. The aim of the current study was to evaluate lytA
gene for the detection of Streptococcus pneumoniae in the cerebrospinal fluid of human patients
with meningitis using real-time PCR assay.

Material and Methods:

In this cross-sectional study, a total of 30 clinical specimens were collected
from patients in a period from September to December 2018. In order to evaluate the presence
of lytA gene, conventional and real-time PCR methods were used without culture.

Results:

From 30 sputum samples, five (16.66%) isolates were identified as S. pneumoniae by lytA
PCR and sequencing.

Conclusion:

In this research, an accurate and rapid real-time PCR method was used, which is
based on lytA gene for diagnosis of bacteria. Based on the sequencing results, the sensitivity for the
detection of lytA gene was 100% (5/5).
DiGeSt. Journal of Diversity and Gender Studies (Vol. 7, No. 1)
Authors: Rahbari Ladan , Goethals Tina , Vandenbroucke Mieke
Published: June 2020

Regular Issue
‘Deviant’ or the consequence of social evolution? Discourses of intentional ‘multiple parenthood practices’ in the Dutch and the Flemish press
Authors: Cammu Nola
Published: June 2020

Practices of ‘intentional multiple parenthood’, by which more than two parents agree to conceive and raise children together, have gained increased news coverage in recent years. This paper explores written press articles concerning intentional multiple parenthood in Belgium and the Netherlands. Through a discourse analysis of press articles, the paper challenges the gendered and dyadic concept of parenthood as an understandable given. Newly developed concepts within the ‘traditional’ framework of parenthood are explicitly presented as ‘new’ and ‘revolutionary’ within the public discourse, yet their existence remains dependent on mainstream conceptual usage and the dominant social relations underpinning them. Furthermore, it has been found that press articles on the topic of multiple parenthood frequently use familiar concepts (such as traditional family values of love and commitment) and existing terminology (such as ‘father’, ‘mother’, ‘donor’) to describe the non-mainstream practice of multiple parenthood despite the lack of recognition for this practice in the legal realm.
Shaping an ethical approach to trans research: Some reflections from my doctoral project
Authors: hartline france rose
Published: June 2020

From 2016 to 2019, I conducted my doctoral project research on trans and gender-diverse experiences in Norway, focussing on the impact of a new law on gender recognition through which the previous sterilisation requirement for legal gender change was overturned. Over the course of this research, I have been exploring what it means to be an ethical feminist scholar and working to foster what I feel is a more ethical approach to research on trans individuals. In this article, I outline what I have found to be essential theoretical and methodological considerations to ethical trans research. I apply these to my own doctoral research process to demonstrate the importance of trans-focussed research, reflecting on the challenges I faced when writing my thesis.
Лимитирующие режимы роста III-V нитевидных нанокристаллов
Authors: Дубровский В.Г. , Соколовский А.С. , Hijazi H.
Published: June 2020

Theoretical analysis is presented for vapor-liquid-solid growth of III-V nanowires in the presence of three competing processes of the group V deposition, surface diffusion of group III adatoms and nucleation of islands at the liquid-solid interface. A generalized equation for the nanowire growth rate is obtained which can be limited of one of the three processes depending on the growth environment. Different regimes of vapor-liquid-solid growth of III-V nanowires are analyzed depending on the group III and V influxes and nanowire radius.
Одноэлектронный транспорт в коллоидных квантовых точках узкозонных полупроводников
Authors: Жуков Н.Д. , Гавриков М.В. , Крыльский Д.В.
Published: June 2020

Single-electron transport in the planar structure of colloidal quantum dots of InSb, PbS, CdSe semiconductors was studied using a scanning tunneling microscope. On the current – ​​voltage characteristics, sections of the current dip were observed similar to the Coulomb gap. Qualitative and numerical comparative estimates suggest that one-electron transport and a phenomenon similar to the Coulomb blockade are observed in the structure of the set of quantum dots. When measuring the current-voltage characteristics, the white-light illumination of the sample breaks the Coulomb blockade, and it can be expected that an instrument element based on such a structure will respond to individual photons. In the region of the Coulomb gap, current oscillations with frequencies in the terahertz range are possible.
Online Conversation Monitoring to Understand the Opioid Epidemic: Epidemiological Surveillance Study (Preprint)
Authors: Black Joshua C , Margolin Zachary R , Olson Richard A , Dart Richard C
Published: June 2020

BACKGROUND

Between 2016 and 2017, the national mortality rate involving opioids continued its escalation; opioid deaths rose from 42,249 to 47,600, bringing the public health crisis to a new height. Considering that 69% of adults in the United States use online social media sites, a resource that builds a more complete understanding of prescription drug misuse and abuse could supplement traditional surveillance instruments. The Food and Drug Administration has identified 5 key risks and consequences of opioid drugs—misuse, abuse, addiction, overdose, and death. Identifying posts that discuss these key risks could lead to novel information that is not typically captured by traditional surveillance systems.

OBJECTIVE

The goal of this study was to describe the trends of online posts (frequency over time) involving abuse, misuse, addiction, overdose, and death in the United States and to describe the types of websites that host these discussions. Internet posts that mentioned fentanyl, hydrocodone, oxycodone, or oxymorphone were examined.

METHODS

Posts that did not refer to personal experiences were removed, after which 3.1 million posts remained. A stratified sample of 61,000 was selected. Unstructured data were classified into 5 key risks by manually coding for key outcomes of misuse, abuse, addiction, overdose, and death. Sampling probabilities of the coded posts were used to estimate the total post volume for each key risk.

RESULTS

Addiction and misuse were the two most commonly discussed key risks for hydrocodone, oxycodone, and oxymorphone. For fentanyl, overdose and death were the most discussed key risks. Fentanyl had the highest estimated number of misuse-, overdose-, and death-related mentions (41,808, 42,659, and 94,169, respectively). Oxycodone had the highest estimated number of abuse- and addiction-related mentions (3548 and 12,679, respectively). The estimated volume of online posts for fentanyl increased by more than 10-fold in late 2017 and 2018. The odds of discussing fentanyl overdose (odds ratios [OR] 4.32, 95% CI 2.43-7.66) and death (OR 5.05, 95% CI 3.10-8.21) were higher for social media, while the odds of discussing fentanyl abuse (OR 0.10, 95% CI 0.04-0.22) and addiction (OR 0.24, 95% CI 0.15-0.38) were higher for blogs and forums.

CONCLUSIONS

Of the 5 FDA-defined key risks, fentanyl overdose and death has dominated discussion in recent years, while discussion of oxycodone, hydrocodone, and oxymorphone has decreased. As drug-related deaths continue to increase, an understanding of the motivations, circumstances, and consequences of drug abuse would assist in developing policy responses. Furthermore, content was notably different based on media origin, and studies that exclusively use either social media sites (such as Twitter) or blogs and forums could miss important content. This study sets out sustainable, ongoing methodology for surveilling internet postings regarding these drugs.
Prediction of COVID-19 Severity Using Chest Computed Tomography and Laboratory Measurements: Evaluation Using a Machine Learning Approach (Preprint)
Authors: Li Daowei , Zhang Qiang , Tan Yue , Feng Xinghuo , Yue Yuanyi , Bai Yuhan , Li Jimeng , Li Jiahang , Xu Youjun , Chen Shiyu , Xiao Si-Yu , Sun Muyan , Li Xiaona , Zhu Fang
Published: June 2020

BACKGROUND

Most of the mortality resulting from COVID-19 has been associated with severe disease. Effective treatment of severe cases remains a challenge due to the lack of early detection of the infection.

OBJECTIVE

This study aimed to develop an effective prediction model for COVID-19 severity by combining radiological outcome with clinical biochemical indexes.

METHODS

A total of 46 patients with COVID-19 (10 severe, 36 nonsevere) were examined. To build the prediction model, a set of 27 severe and 151 nonsevere clinical laboratory records and computerized tomography (CT) records were collected from these patients. We managed to extract specific features from the patients’ CT images by using a recently published convolutional neural network. We also trained a machine learning model combining these features with clinical laboratory results.

RESULTS

We present a prediction model combining patients’ radiological outcomes with their clinical biochemical indexes to identify severe COVID-19 cases. The prediction model yielded a cross-validated area under the receiver operating characteristic (AUROC) score of 0.93 and an F1 score of 0.89, which showed a 6% and 15% improvement, respectively, compared to the models based on laboratory test features only. In addition, we developed a statistical model for forecasting COVID-19 severity based on the results of patients’ laboratory tests performed before they were classified as severe cases; this model yielded an AUROC score of 0.81.

CONCLUSIONS

To our knowledge, this is the first report predicting the clinical progression of COVID-19, as well as forecasting severity, based on a combined analysis using laboratory tests and CT images.
The Importance of Kidney Medullary Tissue for the Accurate Diagnosis of BK Virus Allograft Nephropathy
Authors: Nankivell Brian J. , Renthawa Jasveen , Shingde Meena , Khan Asrar
Published: June 2020

Background and objectives

The published tissue adequacy requirement of kidney medulla for BK virus allograft nephropathy diagnosis lacks systematic verification and competes against potential increased procedural risks from deeper sampling.

Design, setting, participants, & measurements

We evaluated whether the presence of kidney medulla improved the diagnostic rate of BK nephropathy in 2244 consecutive biopsy samples from 856 kidney transplants with detailed histologic and virologic results.

Results

Medulla was present in 821 samples (37%) and correlated with maximal core length (r=0.35; P<0.001). BK virus allograft nephropathy occurred in 74 (3% overall) but increased to 5% (42 of 821) with medulla compared with 2% (32 of 1423) for cortical samples (P<0.001). Biopsy medulla was associated with infection after comprehensive multivariable adjustment of confounders, including core length, glomerular number, and number of cores (adjusted odds ratio, 1.81; 95% confidence interval, 1.02 to 3.21; P=0.04). In viremic cases (n=275), medulla was associated with BK virus nephropathy diagnosis (39% versus 19% for cortex; P<0.001) and tissue polyomavirus load (Banff polyomavirus score 0.64±0.96 versus 0.33±1.00; P=0.006). Biopsy medulla was associated with BK virus allograft nephropathy using generalized estimating equation (odds ratio, 2.04; 95% confidence interval, 1.05 to 3.96; n=275) and propensity matched score comparison (odds ratio, 2.24; 95% confidence interval, 1.11 to 4.54; P=0.03 for 156 balanced pairs). Morphometric evaluation of Simian virus 40 large T immunohistochemistry found maximal infected tubules within the inner cortex and medullary regions (P<0.001 versus outer cortex).

Conclusions

Active BK virus replication concentrated around the corticomedullary junction can explain the higher detection rates for BK virus allograft nephropathy with deep sampling. The current adequacy requirement specifying targeting medulla can be justified to minimize a missed diagnosis from undersampling.
Climate Justice at the Local Level
Authors: Sarıkoç Yıldırım Beyza
Published: June 2020

Climate change is an issue of social justice, as it affects different social groups in the urban space differently. Yet, while formulating climate action plans, local governments often disregard the relationship between climate change and justice. By using content analysis, this article explores climate change action plans of Turkish municipalities from the perspective of climate justice. It concludes that action plans of Turkish municipalities do not consider climate change as a problem of justice despite the emerging or exacerbated inequalities in the urban space caused by climate change.
Program Story Telling dengan Metode BERLIAN (Bercerita-ExpeRiential-LearnIng-ANak) untuk Menanamkan Moral pada Anak-anak
Authors: Iswinarti Iswinarti , Asrini Hari Windu , Hasanati Nida , Kartono Rinikso
Published: June 2020

TPQ (Taman Pendidikan Al Qur’an) merupakan sebuah tempat diselenggarakannya pendidikan dan pengajaran agama Islam khususnya Al Quran, termasuk pendidikan moral. Pada kenyataannya, program pendidikan di TPQ pada umumnya hanya mengajarkan bagaimana membaca Al Quran, tidak mengajarkan isi dan makna dari Al Quran itu sendiri, sehingga pendidikan moral kurang mendapat perhatian. Dengan demikian, hal yang penting yaitu membuat kreasi pada metode pembelajaran penanaman nilai-nilai moral menggunakan metode yang lebih menarik. Metode story telling merupakan salah satu teknik yang menarik untuk mempelajari nilai-nilai moral pada anak-anak. Program ini bertujuan untuk menerapkan metode story telling dengan metode BERLIAN (Bercerita-ExpeRiential-LearnIng-ANak) untuk menananmkan nilai-nilai moral pada anak. Strategi yang digunakan dalam program ini adalah pelatihan dan dilanjutkan dengan pemantauan dan pendampingan. Hasil pelatihan menunjukkan bahwa peserta merasakan pentingnya metode story telling yang diterapkan di TPQ untuk menanamkan nilai-nilai moral pada anak-anak. Mereka juga sepakat untuk menerapkan metode ini di TPQ, tetapi dalam penerapannya mereka terkendala dengan terbatasnya waktu, belum terbiasa, kurangnya keterampilan, dan kurangnya kepercayaan diri. Pendampingan dan tindak lanjut perlu dilakukan agar program dapat diimplementasikan dengan lebih baik.
Family Strength Model dalam Upaya Meningkatkan Ketangguhan Keluarga di Situasi Krisis
Authors: Pertiwi Ratih Eka , Syakarofath Nandy
Published: June 2020

Situasi krisis yang tidak terduga seperti adanya pandemi Covid-19 ini mempengaruhi berbagai aspek kehidupan manusia. Tidak dapat dipungkiri situasi ini dapat mengancam ketangguhan keluarga. Di sisi lain, keluarga merupakan sumber dukungan sosial yang sangat kuat untuk menghadapi situasi krisis. Psikoedukasi berbasis Family Strength Model dapat digunakan untuk mendorong kemampuan keluarga dalam menjaga ketangguhan keluarga di situasi krisis. Program psikoedukasi dilakukan dengan media daring sebagai bentuk yang dirasa efektif dan efisien dalam menjembatani imbauan untuk melaksanakan physical distancing.  Unpredictable crisis as Covid-19 pandemic situation may affect the way people live their life. It can be threatening factor for family strength. On the other hand, family is powerful resource of social support to face any difficulties during crisis. Psychoeducation based on Family Strength Model used to encourage family strength in this situation. Online psychoeducation program was effective and efficient method to do due to physical distancing restriction.
GÖRSEL İLETİŞİM TASARIMINDA BİR İFADE BİÇİMİ OLARAK ÇEKOSLOVAK KUKLA ANİMASYONU
Authors: KINAM Bilge
Published: June 2020

Bu araştırma Çekoslovakya’da 1936 ile 1985 yılları arası yaratılan kukla animasyon filmlerinden bir seçkinin görsel iletişim tasarımında yerini ortaya koymayı amaçlamıştır. Kukla ve objelerle yaratılan Çekoslovak animasyonu, farklı bireysel yaklaşımları, artistik stilleri, şiirsel anlatımı, güçlü hayalgücünün ve yaratıcılığın ön planda olduğu deneysel yaklaşımı ile canlandırma sinemasında önemli bir yere sahiptir. Çekoslovak animasyon tarihinde yer edinmiş animasyon film yönetmenleri; Jiří Trnka, Karel Zeman, Jan Švankmajer, Jiří Bárta’nın animasyon filmleri dönemin sosyo politik olayları ve sinemada kompozisyon öğeleri kapsamında irdelenmiştir. İncelenen kukla animasyon filmlerde gerçeküstücü, hicivli, ironik bir anlatım ile komünizmin baskıcı izleri görülmüştür. Çocuktan yetişkine sihirli bir dünya yaratan Çekoslovak kukla animasyonları, kitlelerin aydınlanmasında ve ulusal dirilişin canlanmasında etkili olmuştur. Araştırma, yabancı yayınlardan, makale ve tezlerden yararlanılarak zengin bir literatür taraması altında ortaya koyulmuştur.
BAĞLAMA ÇALGISINDA NOTA-İCRA FARKLILIKLARINA SEBEP OLAN ETKENLER
Authors: GÖKTAŞ Uğur
Published: June 2020

Bağlama, çok eski bir geçmişe sahip olmakla birlikte geçmişten günümüze çeşitli değişimlere uğrayarak gelişimini sürdürmüştür. Bu süre zarfında, bağlama icrası da şekillenmiştir. Günümüzde ise bağlamada çeşitli icra şekillerine rastlanmaktadır. Bağlamadaki bu icra çeşitliliğinin birçok açıdan problemlere yol açtığı görülmektedir. Araştırmada, bağlama icrasındaki nota-icra farklılıklarına sebep olan etkenlerin tespitine yönelik çalışmalar yapılmıştır. Araştırma durum tespiti yapmaya yönelik olup betimsel bir özellik sergilemektedir. Araştırmada, yazılı ve dijital kaynak taraması ve içerik analizi yapılmıştır. Sonuç olarak bağlama icrasındaki nota-icra farklılıklarının; yöresel üslup ve tavır özellikleri, usta icracılar tarafından geliştirilen yeni icra teknikleri, bağlama icrası öğrenimindeki/öğretimindeki usta-çırak ilişkisi, bağlama icrasına yönelik müzik eğitimi verilen kurum veya kuruluşlarda ortak metodolojik yöntemlerin kullanılmaması vb. gibi etkenlerden kaynaklandığı tespit edilmiş ve bu tespitlerden hareketle bağlama çalgısında nota-icra farklılıklarının giderilmesine yönelik öneriler sunulmuştur.
PANDEMİ SÜRECİNDE BİLGİLENDİRME TASARIMI
Authors: GÜRSU İrem
Published: June 2020

Teknolojik araçların ve dijital platformların gelişmesi ile kitle iletişiminde klasik mecralar yerini hızla yeni nesil dijital mecralara bırakmaktadır. Youtube kanalları, Whatsapp grupları, Facebook, Instagram, Twitter gibi sosyal medya platformları ya da telefonlara yüklenebilen anlık haber uygulamaları ile hızla değişen gündem anlık takip edilebilmektedir. Bu bilgi bombardımanı içinde kimi haberler anında dikkat çekerken içinde çok önemli gelişmeler bile barındırsa birçok haber ve bilgi de görülmeden kapatılıp geçilebilmektedir. İletilen bilginin hızlı ve etkili bir şekilde alıcıya ulaşabilmesinde bilgilendirme tasarımı önemli bir konumdadır. Dünya Sağlık Örgütü’nün 11 Mart 2020’de pandemi ilan etmesiyle tüm dünyada paniğe neden olan Covid 19 ile herkesin önceliği değişirken konu hakkında alınan bilgiler büyük öneme sahiptir. Pandemi sürecinde doğru bilgiye duyulan ihtiyacın giderilmesinde aktif rol üstlenen bilgilendirme tasarımının önemi çalışmanın amacını oluşturmaktadır.
Bu kapsamda bilgilendirme tasarımının gelişimi ve kullanım alanları, pandemi sürecinde doğru ve hızlı bilgi paylaşımının önemi ve kullanılan iletişim mecraları ele alınmıştır. Bu süreçte ülkemizde en çok kullanılan dijital platformlar ve bilgilendirme grafiğine ihtiyaç duyulan alanlar incelenirken, ortaya çıkan tasarımlar, toplum sağlığını göz önünde bulunduran kamu spotları, bireysel olarak tasarımcıların konuyla ilgili kendilerini sorumlu hissetmeleri sonucu yayınladıkları kurallar, tavsiyeler, mesajlar içeren tasarımlar incelenmiştir.
TÜRK SİNEMASINDA DUBLAJ ŞARKILAR: BELKIS ÖZENER ÖRNEĞİ
Authors: DÖNMEZ Yağmur Eylül , İMİK Ünal
Published: June 2020

Türk Sinemasında bir döneme imza atmış olan Yeşilçam filmleri, kendine özgü melodram yapısı ile şarkılı filmler olarak adlandırılan döneminin karakteristik kültürünü hemen her yönü ile yansıtmıştır. Bu dönemde çekilmiş olan filmlerin bir çoğunda zamanın popüler olmuş şarkıcıların başrol oyuncusu olarak sıkça yer aldığı ve film boyunca çeşitli müzik eserlerini seslendiği görülmektedir. İzleyici her ne kadar başrol oyuncusunun sesini dinlediğini düşünse de aslında gerçekte bu eserlerin birçoğu dublaj şeklindedir. Yeşilçam’ın önemli başrol isimlerinden (ses sanatçısı kökenli olmayan) birçoğunun film içerisindeki eser yorumlamaları, dublaj yöntemiyle sağlanmıştır. Bu dönemdeki filmlerde sahnede görmediğimiz halde sesi kulaklarımıza nakşedilmiş en önemli dublaj şarkı yorumcularından birisi de hiç şüphesiz Sayın Belkıs Özener’dir. Araştırmada durum tespiti yapılma yönelik betimsel bir yöntem kullanılmıştır. Araştırma, Belkıs Özener’in icra etmiş olduğu eserlerden hazırlanmış olan “Sahibinin Sesinden Yeşilçam Şarkıları” albümündeki yirmi beş eserle ile sınırlı tutulmuştur. Araştırma verilerinin elde edilmesinde yazılı ve dijital kaynak taraması, uzman görüşleri ve içerik incelemesi tekniklerinden faydalanılmıştır. Araştırma sonuçlarından önemli görülen bazılarından bahsedilecek olursa, şarkı dublajı kavramının genel dublaj tanımlarından farklı bir içeriğe sahip olduğu, şarkı dublajının film içerisinde yer alan şarkıların seslendirilmesi olarak Türk sinema sektöründe ön plana çıktığı ve özellikle Yeşilçam dönemi içerisinde önemli bir yer edinmiş olduğu, Filmlerde şarkı dublajının o dönemde bir meslek halini aldığı, şarkı dublajı alanına Sayın Belkıs Özener’in özveriyle senelerini adamış olduğu, bu alandaki çalışmalarını titizlikle yürüttüğü, kendini geri planda tutmuş olduğu ve Yeşilçam emekçisi olmasına rağmen yıllar sonra dahi kıymetinin yeterince anlaşılmadığı, mesleğine olan saygısının sonucu olarak dublaj ses sanatçılığının tüm diğer kişisel kimliklerinin önüne geçmiş olduğu, Sayın Özener’in yirmiye yakın başrol oyuncusunu film içerisindeki şarkılarını seslendirerek izleyicilerde gerçeklik hissiyatını ziyadesi ile oluşturmuş olduğudur.
THE ANALYSIS OF THE SERVICE QUALITY ON FRONT OFFICE DEPARTMENT IN BALI NUSA DUA HOTEL
Authors: Sanjaya Wayan Kiki , Wijaya A.A. Agung , Aryati Kadek Feni , Rafael Reinaldo
Published: June 2020

This study analyzes the guest satisfaction level of service quality on front office department in Bali Nusa Dua Hotel. As many hotels are emerging up, hence companies being required to improve the service quality on front office department in order to achieve customer satisfaction. In reality, although in generally, the services in Bali Nusa Dua Hotel is good, but having some shortcomings, this became an obstacle in improving the service quality. Therefore, the problem raised in this study is how the service quality and alternative strategies in improving the service quality on front office in Bali Nusa Dua Hotel. This is a quantitative descriptive research. The data of research were obtained from observations, questionnaires, interviews, and documentation studies. The data were further tabulated with the results of the study which found that although the average guest were satisfied with the front office service, empathy is needed to be optimized as one of the alternative strategies and as a screening study that led to the satisfaction of the guests staying overnight.
Keragaman Spesies Vektor Japanese encephalitis di Sekitar Kandang Babi Kabupaten Tangerang
Authors: Riandi Muhammad Umar , Wahono Tri , Ipa Mara , Hendri Joni , Subangkit Subangkit
Published: June 2020

Abstract. Japanese encephalitis is a mosquito-borne zoonotic disease that has pigs as the amplifying host. It is important to study the diversity of mosquito species around pig populations to determine the potential of Japanese encephalitis vectors in the region. This study is a cross-sectional study with a single sampling method for adult mosquitoes around pigpen in Tangerang Regency. The capture of adult mosquitoes is carried out by the outdoor resting mosquitoes collection at 18:00 - 24:00 using aspirators and light traps. Female mosquitoes were identified and subsequently tested RT-PCR for JEV. Catching results obtained 223 mosquitoes from the genus Culex, Armigeres, Aedes, Anopheles, and Mansonia with a total of 10 species. Species diversity in the pigpen area is classified as moderate (H = 1.0875 – 1.292) with Culex vishnui and Culex quinquefasciatus as the most abundant species. RT-PCR test found there’s no mosquito’s samples with positive JE RNA virus. Several species of mosquitoes found around pigpens in Tangerang District have the potential to become JEV vectors, so that control to the mosquito abundance and health of pigs is needed as a preventative measure.

 Keywords: Diversity, Japanese encephalitis, pig, vector

 

Abstrak. Japanese encephalitis merupakan penyakit zoonosis yang ditularkan oleh nyamuk dan babi sebagai inang penguat. Studi keanekaragaman jenis nyamuk di sekitar populasi babi penting dilakukan untuk mengetahui potensi vektor Japanese encephalitis pada wilayah tersebut. Desain penelitian ini adalah potong lintang dengan metode sampling tunggal terhadap nyamuk dewasa sekitar kandang babi di Kabupaten Tangerang. Penangkapan nyamuk dewasa dilakukan dengan metode koleksi outdoor resting pada malam hari pukul 18.00 – 24.00 menggunakan aspirator dan perangkap cahaya. Nyamuk betina diidentifikasi  dan selanjutnya diuji RT-PCR virus JE. Hasil penangkapan didapatkan 700 ekor nyamuk dari genus Culex, Armigeres, Aedes, Anopheles, dan Mansonia dengan total 10 spesies. Keanekaragaman spesies pada seluruh wilayah penelitian tergolong sedang (H=1,0875 – 1,292) dengan Culex vishnui dan Culex quinquefasciatus sebagai spesies paling melimpah. Uji RT-PCR tidak menemukan adanya sampel nyamuk positif RNA virus JE. Beberapa spesies nyamuk yang ditemukan di sekitar kandang babi di Kecamatan Panongan memiliki potensi sebagai vektor JEV sehingga diperlukan pengendalian kepadatan nyamuk dan kesehatan ternak babi terhadap JEV sebagai upaya pencegahan.

 Kata Kunci: Keanekaragaman, Japanese encephalitis, babi, vektor
MANIFESTAÇÕES TORCEDORAS E TERRITÓRIO: CONFIGURAÇÕES DAS IMEDIAÇÕES DA ARENA DO GRÊMIO
Authors: Martins Daiane Grillo , Knuth Alan Goularte
Published: June 2020

Os tempos e espaços referentes às manifestações torcedoras não se restringem ao interior dos estádios de futebol. Assim, buscamos compreender como se configuram as relações de apropriação do espaço das imediações da Arena do Grêmio no período que antecede os jogos no estádio. Realizamos uma pesquisa etnográfica em sete jogos do Grêmio Foot-Ball Porto Alegrense em 2018, com observações, anotações, caminhadas, conversas, fotos, vídeos e diários de campo. Observamos que o público diverso formado por torcedores, comerciantes, policiais, vendedores ambulantes, catadores, entre outros sujeitos, constitui microterritórios em rede, formando a totalidade territorial. O território é mutável nas combinações de clima, tipo e fase da competição, adversário, mas também é estável, nos fatores sociabilidade e relações comerciais. Concluímos que as imediações da Arena do Grêmio é território de ambiguidades, configurado na multiplicidade de inter-relações, significados e pertencimentos.
Donald T. Nicolaisen: An Internationalist SEC Chief Accountant (1944–2019)
Authors: Zeff Stephen A. , Persson Martin E.
Published: June 2020

Donald T. Nicolaisen (1944–2019) was an internationalist, a progressive thinker, and a leader of the U.S. accounting profession. This memorial article traces Nicolaisen's early education and career in the Milwaukee office of Price Waterhouse & Co. in the 1960s, his rise to partner and eventual transfer to the firm's national office in New York City in the 1970s, and his appointment and tenure as the Chief Accountant of the Securities and Exchange Commission in the early 2000s. During his time as the Chief Accountant, Nicolaisen laid the groundwork for the lifting of the reconciliation requirement for foreign private issuers traded on American stock exchanges; the implantation of Sarbanes-Oxley's internal control reporting requirements; and the introduction of XBRL for companies' annual filings with the Commission. Through these initiatives, Nicolaisen leaves behind a legacy of improving both the quality of financial reporting and the efficiency of U.S. capital markets.

JEL Classifications: M41; M42; M48.
The biomechanics of posterior maxillary arch expansion using fixed labial and lingual appliances
Authors: Kaur Harsimrat , Owen Brandon , Tran Bill , Guan Raymond , Luo Jeramy , Granley Alexander , Carey Jason P. , Major Paul W. , Romanyk Dan L.
Published: June 2020

Objective

To compare the biomechanics of straight labial, straight lingual, and mushroom lingual archwire systems when used in posterior arch expansion.

Materials and Methods

An electro-mechanical orthodontic simulator allowing for buccal–lingual and vertical displacements of individual teeth and three-dimensional force/moment measurements was instrumented with anatomically shaped teeth for the maxillary arch. In-Ovation L brackets were bonded to lingual surfaces, and Carriere SLX brackets were bonded to labial surfaces to ensure consistency of slot dimensions. Titanium molybdenum archwires were bent to an ideal arch form, and the teeth on the orthodontic simulator were set to a passive position. Posterior teeth from the canine to second molar were moved lingually to replicate a constricted arch. From the constricted position, the posterior teeth were simultaneously moved until the expansive force decreased below 0.2 N. Initial force/moment systems and the amount of predicted expansion were compared for posterior teeth at a significance level of α = 0.05.

Results

Archwire type affected both the expected expansion and initial force/moment systems produced in the constricted position. In general, the lingual systems produced the most expansion. The archwire systems were not able to return the teeth to their ideal position, with the closest system reaching 41% of the intended expansion.

Conclusions

In general, lingual systems were able to produce greater expansion in the posterior regions when compared with labial systems. However, less than half of the intended arch expansion was achieved with all systems tested.
A inscrição da escrita na criança: relação do sujeito com as rasuras em textos copiados
Authors: Schavarem Letícia Do Nascimento , Aspilicueta Patricia , Galli Juliana Marcolino , Cordeiro Michelly Daiane de Souza Gaspar
Published: June 2020

Introdução: Este estudo pretende discutir o funcionamento das rasuras e sua relação com a criança em processo de aquisição da escrita, visto que estas são marcas de um conflito entre o sujeito e a linguagem. A reflexão é sustentada pela perspectiva Interacionista em aquisição de linguagem, proposta por Cláudia De Lemos, com aproximações à Clínica de Linguagem. Objetivo: Apresentar e discutir as rasuras nos textos escritos por duas crianças que possuem dificuldades no processo de aquisição da escrita. Métodos: O estudo segue uma diretriz qualitativa e busca metodologicamente investigar a escrita do ponto de vista linguístico e subjetivo. Os dados para análise são textos e filmagens de duas crianças, coletados em um grupo que envolvia leitura de histórias e escrita. Esse grupo foi organizado e direcionado sem fins terapêuticos pela pesquisadora que é também fonoaudióloga. Resultados: Alguns textos apontam para um aprisionamento ao texto original, havendo uma insatisfação e estranhamento pelo efeito de não apresentar o texto igual, assim como pelo efeito da escuta/leitura imaginária afetada pelo discurso escolar. Por outro lado, há textos em que o estranhamento se refere ao imaginário de uma posição na linguagem, tomando uma posição de escuta/leitura em que o sujeito é cindido entre fala/escrita (operação simbólica e inconsciente) e escuta/leitura. Conclusão: Os movimentos são subjetivos e dizem de uma relação do sujeito com a escrita, possibilitando a discussão do que envolve a criança quando rasura e repete o texto do outro.
Esforço auditivo e registro do controle parassimpático do coração durante o reconhecimento de sentenças: estudo piloto
Authors: Guijo Laura Mochiatti , Góes Viviane Borim de , Horiuti Mirella Boaglio , Valenti Vitor Engrácia , Cardoso Ana Cláudia Vieira
Published: June 2020

Introdução: Medidas psicofisiológicas do sistema nervoso autônomo em resposta a tarefas auditivas podem fornecer um meio de quantificar os efeitos do esforço auditivo. Objetivo: Comparar a modulação parassimpática da frequência cardíaca em situações de escuta distintas e determinar se a variabilidade da frequência cardíaca (VFC) é um índice psicofisiológico sensível para mensurar o esforço auditivo. Método: Estudo piloto, observacional, transversal e prospectivo. Participaram 14 adultos normo-ouvintes, de ambos os sexos e com idade entre 18 e 30 anos. Estes responderam a anamnese e realizaram audiometria tonal limiar para verificação de limiares auditivos. Para o registro da VFC, colocou-se a cinta do cardiofrequencímetro na região do processo xifoide e este registro foi coletado por 10 minutos para três situações distintas: “repouso”, “recuperação pós-reconhecimento de sentenças no silêncio” e “recuperação pós-reconhecimento de sentenças no ruído”. O reconhecimento de sentenças foi realizado utilizando-se duas listas de sentenças, de forma randomizada, binaural, nas situações de escuta silêncio e na relação sinal/ruído de -5 dB e, também foi registrada VFC por um período de dois minutos. Aplicou-se o teste de ANOVA de medidas repetidas seguido pelo pós-teste de Bonferroni para comparar o índice de RMSSD nos diferentes momentos de registro da VFC. Resultados: A análise estatística demonstrou que não houve diferença significante do registro da VFC nos diferentes momentos, inclusive durante a tarefa de reconhecimento de sentenças no ruído, considerada a tarefa mais árdua. Conclusão: Para esta amostra, o registro da VFC não foi considerado um índice sensível para a mensuração do esforço auditivo.
Desempenho Lexical e diferenças regionais no vocabulário expressivo em crianças de 3 a 6 anos de uma creche-escola pública no nordeste
Authors: Feitosa Antonio Lucas Ferreira , Melo Andresa Mayra da Silva , Araújo Maria Érika dos Santos de , Santos Gabriella Silvino dos , Souza Thais Nobre Uchôa , Costa Priscila Rufino da Silva
Published: June 2020

Objetivo: Descrever o desempenho lexical e caracterizar as diferenças regionais existentes no vocabulário de crianças de uma região do país que não dispõe de valores de referência para a prova de vocabulário. Métodos: O corpus desta pesquisa foi constituído por cem crianças entre 3 e 6 anos avaliadas por meio do Teste de Linguagem Infantil – Prova de Vocabulário. As avaliações foram gravadas e os dados foram transcritos ortograficamente. Foram aplicados os testes de Mann-Whitney para comparações entre os gêneros e Kruskal-Wallis para comparação entre as faixas etárias e turmas, o teste Anova one-way para comparação da Designação verbal usual entre as faixas etárias e o teste T – amostra única para comparações entre as médias de Designação verbal usual obtidas e o percentual esperado pelo teste, por fim, foi realizada a análise descritiva para os vocábulos. Resultados: Houve diferença significativa no desempenho das médias de Designação verbal usual e Processos de Substituição entre as turmas e faixas etárias. Dentre as categorias semânticas, vestuário e lugares apresentaram-se como mais propensas à variação. Animais foi considerada a melhor categoria. Dentre as categorias semânticas, lugares apresentou todos os vocábulos com desempenho de designação verbal usual abaixo. Conclusão: As crianças apresentaram desempenhos diferentes em função da faixa etária e turma escolar, porém semelhantes quanto ao gênero. Houve presença de um número elevado de variações lexicais, demonstrando a necessidade de testes que contemplem a diversidade sociolinguística e cultural existente no país.
Patient with cardioembolic stroke: clinical characteristics and typical features
Authors: Efimova O. I. , Sergeeva M. A. , Pavlova T. V. , Garkina S. V. , Khokhlunov S. M. , Lebedev D. S.
Published: June 2020

Aim. To evaluate basic clinicopathologicalcharacteristics of patients with atrial fibrillationand pharmacological anamnesis at the time of cardioembolicstroke.

Material and Methods. Study included 99 patientswith atrial fibrillation admitted to SeredavinSamara Regional Clinical Hospital due to cardioembolicstroke. The follow-up duration was 1year.

Results. The average age of the patients was69.1 ± 8.7 years. Patients with atrial fibrillationand acute cardioembolic stroke were characterizedby multimorbidity. Arterial hypertension, chronickidney disease, and diabetes mellitus were diagnosedin 96/99 (97.0%), 60/99 (60.6%), and 22/99(22.2%) patients, respectively. Average risk scoreaccording to the CHA2DS2-VASc scale before admissionwas 4.51 ± 1.2 points; therefore, 96 patientshad indications for anticoagulant therapy (≥2 points on the CHA2DS2-VASc scale). However,adequate prevention of thromboembolic complicationsbefore admission was carried out only in16/99 (16.2%) patients.

Conclusion. These results demonstrate a lowquality of outpatient care in patients with atrialfibrillation. Most likely, this can be explained bythe lack of awareness about the risks of potentialcomplications and low compliance.
PERGESERAN PERILAKU WAMA-WAMA (STUDI ATAS PARA PENCARI SEDEKAH DI KECAMATAN BONANG DEMAK)
Authors: Mustaqim Muhamad
Published: June 2020

This study attempted to investigate the behavior of charity seekers in several villages in Bonang Demak sub-district. This study tried to compare the study that the author conducted seven years before, with wider object and focus of research. The study used a sociological and anthropological approach. The findings revealed that there was a shift in alms seeker behavior mode. First, the letter or proposal model has not been used anymore, although sporadically some still use this model. Second, the model of selling calendars was a model widely used, since it was more elegant. There were products sold like businesses, and minimize the prejudice of fraud as already existed. The model of selling calendars was actually the use of new packages of old content, namely exploiting religion for economic purposes. The implication was that the community did not need to hesitate if they did not want to give / to buy alms to the citizens.
Toward Sovereign Indigenous Justice: On Removing the Colonial Straightjacket
Authors: McGuire Michaela Mary , Palys Ted
Published: June 2020

Canada has oppressed Indigenous peoples capacity for true sovereignty through colonialism, genocide and attempted assimilation. This devastation manifests in the disproportionate social ills facing Indigenous peoples and their overrepresentation at all levels of the imposed criminal justice system (CJS). Trauma and internalized colonialism have constrained the capacity of Indigenous Nations to reclaim their place in the world as self-governing peoples. Canada has attempted to ‘fix’ this problem through creating parallel systems, trying to fit ‘Indigenous’ conceptions of justice into existing systems, and problematically adopting restorative justice as synonymous with Indigenous justice. The rhetoric of reconciliation and apology mask the continual genocidal, assimilative goals of the state. With these caveats in mind, the need to reject internalized colonialism and develop capacity for the development of sovereign Indigenous justice systems will be examined.