bluuebunny/crossref_metadata_2025 huggingface dataset:
Python İle Mini Jel Elektroforez Kontrol Yazılımı Ve Sistem Tasarımı
Authors: KAVSAOĞLU Ahmet Reşit , MERSİNKAYA İsmail
Published: December 2019

DNA, RNA ve protein molekülleri gibi yüklü makro moleküllerin bir elektrik alan içerisinde (-) ve (+) yüklü kutuplar arasında bir kutuptan diğerine doğru hareket ettirilerek ayrıştırılması yöntemine elektroforez denir. Klasik elektroforez işleminde güç kaynağı, UV (morötesi) transillüminatör ve jel görüntüleme için kullanılan cihaz ve malzemeler, süreç kontrolü işlemleri birbirinden ayrı işlemler olarak ve deneyi yapan kişiler tarafından yapılmaktadır. Gülümseme etkisi (smile effect), yayınım etkisi ve diğer etkiler analizlerdeki hassasiyeti düşürebilmekte ve sonuçlar üzerinde hatalı band görüntüsü ve band yoğunluğu hesaplamasına neden olabilmektedir. Bu çalışma, elektroforez işlemi süresince güç kaynağının gerilim dalgalanmasından ve deneyi yapan kişilerin zamanında güç kaynağını kapatmadığında bandların jel dışına taşması gibi hataları en aza indirerek analiz hassasiyetini arttırmayı; kullanılan cihazların işlem sırasına göre çalışabilmesi ve hesaplama işlemlerinin otomatik olarak bir mikroişlemci ve mikrodenetleyici arabirimleri tarafından yapılabilmesini sağlayan kontrol yazılımı, mini jel elektroforez sistem tasarımı ve uygulama çalışmalarını içermektedir. Tasarlanan kontrol yazılımı ve klasik elektroforez ile yapılan işlemler karşılaştırıldığında olumlu sonuçlar elde edildiği görülmüştür.
Biyoçeşitlilik Sıcak Noktası ve Jeolojik Miras Alanı Olan Karstik Peyzajların Zamansal Değişimi: Çankırı Jipsli Tepeleri
Authors: ÖZCAN Ali , AYTAŞ İbrahim
Published: December 2019

Jipsli topraklar dünyada geniş alanlara yayılmış olup jeolojik ve biyolojik çeşitlilik açısından özel alanlardır. Jipsli alan habitatları ve jeolojik yapısı, jips içeriğinden dolayı kırılgandır. Bu bölgeler, arazi kullanım değişiklikleri, hayvancılık, otlatma, su kaynaklarının aşırı kullanımı gibi insan faaliyetleri tarafından tahrip edilmektedir. Bu çalışmada; Çankırı'daki jeolojik, ekolojik, biyolojik ve paleontolojik bakımdan önem taşıyan jipsli alanların 2008-2014 yılları arasındaki peyzaj değişimi analiz edilerek, bölgedeki jeolojik miras alanlarına (dolin gölleri gibi) ve hassas endemik bitki türlerine olan tehdidin ortaya konulması amaçlanmıştır. Bu doğrultuda, 2008 yılı için ortofoto görüntüleri ve 2014 yılı için Göktürk-2 uydu görüntüleri kullanılmıştır. Çalışmanın sonuçları tarım alanı ve yerleşim alanının arttığını, buna karşın dolinlerin, mera ve çayırlık-otlak alanların azaldığını göstermiştir. Biyoçeşitlilik ve jeolojik miras için önemli olan jipsli bölgeler, kısa sürede bile ciddi zararlar görebilmektedir. Sonuç olarak, jipsli toprakları korumak için hızlı bir şekilde önlem almak gerekmektedir.
Biberde Phytophthora Yanıklığına Karşı Antagonist Bakterilerle Biyolojik Mücadele
Authors: ÖZYILMAZ Ümit
Published: December 2019

Bu çalışma ile biberde Phytophthora yanıklığı hastalığına karşı antagonist bakteriler ile biyolojik mücadele olanakları araştırılmıştır. Biyolojik mücadele çalışmalarında kullanılmak üzere biber köklerinden antagonist bakteri adayları izole edilmiştir. Daha sonra antagonistlerin hastalık etmenine karşı olan antimikrobiyal etkileri ikili kültür, kökçük testi, saksı ve tarla denemeleri ile değerlendirilmiştir. Çalışmalar sırasında toplam 95 adet antagonist bakteri izolatı elde edilirken, bunlardan 21 tanesi ikili kültür testlerinde hastalık etmeninin misel gelişimini %20-82 oranında engellemiştir. Kullanılan antagonistlerin yapılan kökçük testlerinde hastalık çıkışını %93’e varan bir oranda engellemek suretiyle etkili olduğu saptanmıştır. Yapılan saksı denemelerinde test edilen antagonistlerden bazıları hastalık etmenini engellerken bazılarının da hastalık şiddetini arttırdığı bulunmuştur. Biyolojik mücadelenin değerlendirildiği tarla denemelerinde ise ümitvar sonuçlar elde edilmiştir.
Factors Influencing Entrepreneurial Intentions of Undergraduate Agricultural Students in Nigeria
Authors: ADEYONU Abigail , BALOGUN Olubunmi , OBANIYI Kayode
Published: December 2019

Nigeria is an agrarian economy and the recognition of entrepreneurship as a mover of national development has made it to gain popularity in her educational system in recent years. This study focused on the factors influencing Entrepreneurial Intentions (EIs) of undergraduate agricultural students in Nigeria using Theory of Planned Behavior (TPB). Well structured, pre-tested questionnaire was used to gather relevant information from final year undergraduate agricultural students in private, state and federal government owned universities in Nigeria using multistage sampling techniques. The data were analysed with descriptive statistics, factor analysis and multiple regression model. The results showed that personal attitude towards entrepreneurship, subjective norms and perceived educational support were the main factors influencing students’ EI positively at (P<0.01). Arising from this revelation, the study recommended the development of positive attitude towards becoming entrepreneurs as well as enhancement of educational facilities in the universities to improve students’ EI.
Les Slaves du sud au prisme des Lumières et du romantisme
Authors: Tatin-Gourier Jean-Jacques , Nikcevic Jasmina , Bogojevic Dragan
Published: December 2019

Les auteurs s’intéressent à l’impact culturel français dans la péninsule balkanique entre 1750 et 1850  au travers des figures de passeurs culturels (Velestinlis, Boskovic, Zoïs)  mais aussi de lieux de convergences et de diffusion d'idées (Raguse, Laybach, Vienne) ayant contribué au développement identitaire des Slaves du sud. Les effets de cette diffusion resteront assez méconnus en France jusqu'à la moitié du XIXe siècle où se développe alors un intérêt académique pour la slavistique.
Marriage Ceremony in Batak Toba Tribe: Between Consumerism and Purpose of Life
Authors: Siregar Mangihut
Published: December 2019

The marriage ceremony for the Batak Toba tribe is a bond between a man and a woman along with relatives of men and women. Through marriage ceremonies they can enter the dalihan na tolu system, carry out a life cycle, become adults and have the right to enter the Batak lineage (tarombo). Because of the importance of the meaning of the marriage ceremony, the Batak Toba people continue to carry out this tradition.

According to the tradition of the ancient people, the marriage ceremony was carried out simply by mutual cooperation. In accordance with its development, the marriage ceremony changed from simple to consumerism. Consumerism occurs in mindset, behavior and also matter. Consumer behavior is influenced by: globalization, lifestyle, popular culture and a lack of understanding of the meaning of the Batak Toba marriage ceremony.

The phenomenon of consumerism that occurs in the Batak Toba wedding ceremony is very complex because it follows a long procession at a high cost. Although the behavior of consumerism has long been a problem, but in reality they remain immersed in a culture of consumerism . The culture of consumerism on the one hand is a problem but on the other hand is an arena to achieve purpose of life.
ROUSSEAU: INDIVÍDUO, REPÚBLICA E EDUCAÇÃO
Authors: Silva Antonio Cesar Ferreira da
Published: December 2019

Ao se focalizar o homem, é inevitável tocar na questão de sua formação e da educação, questões que fazem parte da tradição filosófica iniciada por Platão em sua obra A República. Tradição que também é mantida por Rousseau em suas obras. A ênfase que se dá ao assunto gira em torno da adaptação do homem a um determinado contexto, sobretudo ao contexto de uma República, o que pode ser definido a partir de uma pergunta: que processo formativo seria adequado à formação do homem para que ele pudesse se realizar neste contexto? A partir desta pergunta, o presente trabalho buscou discutir a importância da formação como mecanismo para preservar a constituição do indivíduo, a qual possibilite a este a construção de sua própria realização. O caminho metodológico foi percorrido através da análise de duas obras de Rousseau, são elas Emílio ou Da educação e Do contrato social. No Emílio, o filósofo de Genebra aponta para um indivíduo que tem a possibilidade de superar a perspectiva de dependência marcada pela vida em sociedade. Desta forma, se procura apresentar o quão importante é a formação do indivíduo para que ele possa garantir a manutenção e a construção de uma estrutura social, de uma república, que lhe possibilite a sua realização. A estrutura social só poderá se sustentar com a atuação de indivíduos que tenham a si próprios. Isto significa que durante o processo formativo a constituição do indivíduo deve ser assegurada. Só tem a posse de si, quem tem sua constituição mantida por um rigoroso processo formativo. Assim, na medida em que os indivíduos são formados para assumirem uma postura de não dependência, os mesmos terão condições de construírem uma república, cuja dinâmica irá fortalecer a realização de todos os seus membros.
ROUSSEAU E O COURSIER INDOMPTÉ
Authors: Costa Israel Alexandria
Published: December 2019

O presente artigo expõe uma leitura em torno de Jean-Jacques Rousseau que possa servir de contributo à pesquisa contemporânea junto a sua obra. A metodologia aplicada a essa leitura é o da análise histórico-filosófica e hermenêutica, com vistas a desvendar a significação ética de uma passagem do Discours sur l’origine et les fondemens de l’inégalité parmi les hommes que trata do "coursier indompté", noção pouco explorada que, no texto original, articula-se com as noções de "homme barbare" e "orageuse liberté" para, respectivamente, formar um bloco de oposição ao "cheval dressé", ao "homme civilisé" e à "assujettissement tranquille". A hipótese de trabalho que inspira o desenvolvimento desta investigação é a de que o exame que evidencia as peculiaridades da crítica rousseauniana ao mal-estar da civilização e à moral social do seu século se constitui em via de conhecimento para aspectos fundamentais da inteira filosofia de Rousseau, assim como das questões de ética que o autor formulou de modo a jamais perderem a sua força e a sua atualidade.
HABERMAS VERSUS APEL: ACERCA DA INTERPRETAÇÃO DA UNIVERSALIDADE DO CONTRATO SOCIAL
Authors: Oliveira Juliano Cordeiro da Costa
Published: December 2019

Nosso artigo objetiva debater as interpretações de Jürgen Habermas e de Karl-Otto Apel acerca da possível universalidade presente na obra Do Contrato social, de Rousseau. Segundo Habermas, Rousseau e Kant tentaram articular a união prática e a vontade soberana no conceito de autonomia, de modo que a ideia dos direitos humanos e o princípio da soberania popular se interpretassem mutuamente. Mesmo assim, para Habermas, eles não conseguiram entrelaçar simetricamente os dois conceitos. Kant, de acordo com Habermas, sugeriu um modo de ler a autonomia política que se aproximou mais do liberalismo, ao passo que Rousseau do republicanismo. Habermas defende uma possível universalidade no pensamento de Rousseau, a partir de uma síntese com Kant. Dessa maneira, a autonomia privada e a pública pressupõem-se mutuamente, sem que os direitos humanos possam reivindicar um primado sobre a soberania popular, nem esta última sobre os direitos humanos. Ambos seriam, para Habermas, princípios complementares, e não necessariamente antagônicos entre si. Todavia, Karl-Otto Apel considera a posição de Habermas, de uma síntese entre Kant e Rousseau, passível de sérias críticas. Ele enfatiza que a soberania do Contrato social de Rousseau, como soberania de um estado particular, não pode ser identificada com a concepção de vontade geral. A postura de Rousseau, segundo Apel, nos levaria inevitavelmente ao nacionalismo, e não ao universalismo, como em Kant. Apel considera que há, em Rousseau, um particularismo intrínseco do princípio da soberania popular incompatível com os direitos humanos, enquanto Habermas defende a cooriginalidade entre direitos humanos e soberania popular. Este artigo pretende discutir, portanto, como os dois representantes da chamada Ética do Discurso interpretam o pensamento de Rousseau.
PERFECTIBILIDADE, LIBERDADE E EDUCAÇÃO EM ROUSSEAU
Authors: Nodari Paulo César
Published: December 2019

O objetivo deste ensaio é apresentar três conceitos-chave do pensamento rousseauniano: perfectibilidade, liberdade e educação. Trata-se de uma breve elucidação desses três conceitos, a fim de entender melhor a notável passagem do estado de natureza ao estado civil em Rousseau.
Suullisen perinteen arkistoaineistot ja kirjoituksen transmissioon liittyvä variaatio – Antti Rytkösen keräämät rekilaulut Suomalaisen Kirjallisuuden Seuran arkiston kokoelmissa
Authors: Karhu Hanna
Published: December 2019

Artikkeli käsittelee rekilaulumuistiinpanojen variaatiota Antti Rytkösen 1890-luvulla keräämien aineistojen avulla. Kyseiset aineistot ovat Suomalaisen Kirjallisuuden Seuran arkiston kokoelmissa. Artikkelissa verrataan arkistossa olevia erilaisia kirjoitettuja versioita samoista lauluista ja osoitetaan, että perinnearkistojen tekstianeistoissa on havaittavissa kirjoituksen prosesseihin liittyvää variaatiota. Rytkönen on siis muunnellut keräämiään laulutekstejä jonkin verran, ennen niiden lähettämistä SKS:n arkistoon.

Artikkelissa hyödynnetään tekstikritiikin ja geneettisen kritiikin näkökulmia.
Regime-Building through Controlled Opening
Authors: Anceschi Luca
Published: December 2019

This article aims to locate the version of authoritarianism developing in post-Karimov Uzbekistan to current debates on the emergence of new forms of authoritarian governance within and beyond post-Soviet Eurasia. To this end, the article re-evaluates Shavkat Mirziyoyev’s policies in light of authoritarian modernisation theory, revealing how the ultimate end of the process of political change currently at play in Uzbekistan is connected with an upgrading of local authoritarian practices rather than to the liberalisation of the domestic political landscape.
L’Ucraina alla ricerca di un equilibrio
Authors: Franco Andrea , Rumjancev Oleg
Published: December 2019

Con la Rivoluzione della Dignità (2014) un’ampia rappresentanza della popolazione dell’Ucraina si è pronunciata a favore di una collocazione geopolitica nell’UE e nella NATO. In parallelo, la Russia è intervenuta in Crimea e nel Donbas. La società ucraina, oltre ad affrontare le conseguenze di un conflitto e di una situazione geopolitica delicata, sta cercando un proprio equilibrio socio-politico interno, come dimostra l’avvicendamento Poroshenko-Zelens’kyj. La presente raccolta di studi, che coinvolge studiosi italiani, si concentra sui risvolti di carattere storico, giuridico, linguistico, culturale e religioso che accompagnano questo assestamento.
Su alcuni punti nodali della questione ucraina (XIX-XXI secolo)
Authors: Lami Giulia
Published: December 2019

The chapter analyses the “Ukrainian Question”, through examples of old and new analyses on Ukrainian identity, starting from an essay written by the British historian A.J. Toynbee in 1916, when the result of the WW1 and the future of Ukraine was still uncertain. Toynbee’s assumptions are compared with interpretations given by various authors from 19th up to 21st centuries, showing that the crux of the matter is still debated by conteporary analysts. In conclusion, it is expressed the hope that the new presidency could take significant steps in order to consolidate the Ukrainian sovereignity in a peaceful perspective of democratic development.
The Conflict in Donbas: Evolution and Consequences
Authors: Pishchikova Kateryna
Published: December 2019

This chapter focuses on the military conflict in the Donbas area of Ukraine over the period from February 2014 to April 2019 that spans from the beginning of the conflict to the end of the Presidency of Petro Poroshenko, Ukraine’s post-Euromaidan president. By process-tracing the conflict, it brings to light its hybrid nature and argues that the conflict is a result of destabilization tactics, military and political, and of failed diplomatic attempts by state and non-state actors on both sides. In other words, neither the nature nor the territory of the conflict had been preordained at its start and its current shape does not reflect pre-existing societal or identity cleavages.
Gabbroides of Peterman island (West Antarctica). First information on geochemistry
Authors: Artemenko G. V. , Ganotskiy V. I.
Published: December 2019

Peterman Island is located in the archipelago of the Wilhelm Islands on the west coast of the Antarctic Peninsula (Graham Land). It is composed of gabbroids and granitoids of the Andean complex, which formed almost 100 million years later than the volcanic group of the Antarctic Peninsula. To clarify their genesis and geodynamic conditions of formation, gabbroids of the Andean complex are of particular interest, since the petrological models of their formation are well developed. Gabbroid intrusions comprise small bodies that are widespread along the Antarctic Peninsula. Among them stand out olivine gabbros, normal gabbros, norites and hornblende gabbros. Also are found small bodies of melanogabbro-pegmatites and intramagmatic dykes, that are associated with the manifestations of ore mineralization of magnetite, ilmenite and sulfides. For this reason, they are of interest for both the minerals search and for solving the question of their genesis. To this end, we performed geochemical studies of Peterman Island gabbroids. Gabbroids of Peterman Island are represented by amphibolized medium-grained gabbro with hypidiomorphic texture. Among them, xenoliths of thinly stratified gabbroids 3 × 8 m in size were found, which are characteristic of stratified intrusions, for example, Stillwater, Bushveld, etc. Gabbroids of Peterman Island have low content of silica and potassium and according to the petrochemical characteristics correspond to peridotite gabbro. They have low contents of Cr, Ni, V and high strength lithophilic Y and Nb elements. Gabbroids have been crystallized from basic magma, differentiated in the intermediate crustal magma chambers. Positive anomalies of Sr, Eu, and Ti in the multielement diagrams and positive anomalies of europium Eu/Eu* suggest the accumulation of plagioclase and apparently, ilmenite in the magmatic chamber. The primary magma source for gabbroids was probably the primitive mantle (PM). Gabbroids are contaminated with crustal matter. This contamination is probably due to their regressive metamorphism, caused by the introduction of later intrusions of Andean complex granitoid. Finely layered xenolithic gabbroids do not differ from other homogeneous gabbros of Peterman Island in terms of chemical composition.This xenolith most likely represents a part (fragment) of the wall of the magma chamber in which the differentiation of the initial main magma took place. According to the obtained geochemical data, a wide range of compositions of the Andean complex gabbroids formed as a result of crystallization differentiation of magma melted from rocks of the composition of the primitive mantle (PM) in crustal magma chambers, which also resulted in the accumulation of ore elements — V, Co, and Cu in the residual magmatic melts.
Assessment of accumulation of petroleum hydrocarbons by the hydrobionts of the south-eastern part of the Onega bay of the White sea
Authors: Neverova N. V. , Vorobyeva T. Ya. , Chupakov A. V.
Published: December 2019

In order to assess the current state of the ecosystem of the southeast of the Onega Bay of the White Sea affected by fuel oil spill in 2003, the accumulation of petroleum hydrocarbons was analyzed by the dominant species of aquatic organisms collected on the littoral of the most polluted coast in the areas of Purnem and Lyamts villages. In 2012, samples of aquatic organisms were taken in an area where all the species discussed in this work are represented on a small area: bivalved mollusks, attached molluscs, gastropods, polychaetes. In 2013 and 2018, samples of hydrobionts were additionally selected, in the three-kilometer strip of the coast on either sides of the givin point. In 2012 and 2013, high concentrations of HC in the tissues of bivalves were recorded. In 2018, the concentrations of hydrocarbons in the tissues of the studied hydrobionts were comparable to background values. A non-parametric test of Mann-Whitney showed a significant decrease in НС in mussel tissue from 2013 to 2018, at a significance level of 0.05. Taking into account the low levels of HC in the aqueous medium (less than 1 MPC of fishfarm) and in bottom sediments (from 0.34 to 9.03 mg/kg, the median of 1.41 mg/kg) in 2018, and is comparable with the background contents of hydrocarbons in tissues of aquatic organisms. We can conclude that after 15 years of the fuel oil spill, the condition of the Cape Deep ecosystem in terms of the content of hydrocarbons returns to the baseline state, continuing emissions of oil-sand lumps do not adversely affect the ecosystem. Based on the work done, it can also be concluded that ecotoxocological methods are priority in assessing the prolonged (or delayed) accidental impact of heavy petroleum products on aquatic ecosystems. The conclusion about the presence or absence of a negative impact on the aquatic ecosystem of hydrocarbons, based solely on the analysis of abiotic components, may not be sufficiently informative because it does not take into account the accumulative and deferred effects, especially manifested in the cold Arctic waters.
PENGARUH FOCUS GROUP DISCUSSION TENTANG PELAKSANAAN UJI KOMPETENSI TERHADAP TINGKAT KECEMASAN MAHASISWA
Authors: Situmorang Benny Andreson , Silalahi Kristina L
Published: December 2019

 The Indonesian National Competency Test (INCT) is carried out with the aim of equalizing the quality standards of graduates at each educational institution. For INCT students is a challenge that must be faced because to apply for a job a health worker must have a registration certificate (RC). The registration certificate is obtained if a student is declared a graduate (competent) in the implementation of Competency Test. The purpose of this study is to obtain information on the problems being faced by professional nurses who will face the Indonesian National Competency Test through the implementation of Focus Group Discussion (FGD). This type of research is qualitative research with a quasi-experimental research design with one group pretest-posttest design. Stages of Research Methods will be carried out using the design of the quasi-experiment(quasi-experimental) with the target of all nurses in the final semester of totaling 51 people. Data collection method with guided interview guidance. The data analysis method uses dependent t-test. Where in the paired groups, the same subject was examined before and after the intervention (design before and after) and at the same time. Based on the results of the t-test calculation, the value of Z -4,472 with (p = 0,000) <0.05 so that the decision of the hypothesis Ha is accepted then H0 is rejected. It was concluded that there was an influence between FGD (Focus Group Discussion) on the Implementation of Competency Tests on the anxiety level of Nurse Profession students at FKK UNPRI Medan in 2019. It is expected that students who will face competency tests to prepare themselves more by following guidance both on campus and outside campus so have good preparation in facing the Competency Test

 Keywords:  Focus Group Discussion, implementation, competence, test, anxiety level
ANALISIS PELAYANAN TERAPEUTIK TERHADAP KEPATUHAN PASIEN TUBERCULOSIS RESISTEN OBAT DI WiILAYAH KERJA PUKESMAS KOTA MEDAN
Authors: Ayu Mayang Sari
Published: December 2019

Abstract

Adherence patient in the treatment of second-line tuberculosis is the success of controlling drug resistant tuberculosis. Data from the World Health Organization report (2017) only about 66% of drug-resistant tuberculosis patients follow second-line treatment until recovery. WHO places Indonesia at level eight among countries with high burden with drug-resistant tuberculosis in the world. Objective: Analyze therapeutic service of adherence patient drug resistant tuberculosis treatment. Subjects and Methods: This type of research uses observational analytic cross sectional design, conducted at 3 microscopic referral community health centers in the city of Medan. The sample of the study consisted of 32 patients with total sampling technique. The independent variables were medical services, pharmaceutical services, and nursing services. The dependent variable is adherence patient drug resistant tuberculosis treatment. Sources of research data from primary data through structured interviews and secondary data from a review of the patient's medical record. Data analysis used chi square tests and multiple logistic regression tests with a confidence level of 95%. Results: The analysis shows that all variables have a significant relationship between therapeutic services and adherence patient with drug resistant tuberculosis treatment. Analysis of the variables of medical services (p=0.002), pharmaceutical services (p=0.020), and nursing services (p=0.003) affect the compliance of patients undergoing second-line tuberculosis treatment. Conclusion: Teraupetic service variable had a significant effect on adherence patient drug resistant tuberculosis treatment (p> 0.05). The therapeutic service effort at the community service center is providing easy access to services, overcoming side effects of treatment, active case treatment TB officers and family psychosocial support.

Keywords: Therapeutic Services, Drug-Resistant Tuberculosis, Medical Services, Pharmaceutical Services, Nursing Services
ANALISIS KEPUASAN PASIEN KULIT KELAMIN TERHADAP PELAYANAN FARMASI DI RSUD Dr. RM. DJOELHAM
Authors: Hervina Hervina , Harahap Juliandi , Syamsul Darwin
Published: December 2019

Penilaian mutu pelayan kesehatan antara lain dimensi kehandalan(reliability), daya tanggap(responsiveness), jaminan(assurance), empati(emphaty) , dan bukti fisik (tangible). Penelitian ini dilakukan karena menurunnya kunjungan pasien yang berobat jalan ke klinik kesehatan kulit dan kelamin dalam setahun ini, hal ini apakah ada hubungannya dengan ketidakpuasan pasien terhadap pelayanan farmasi, karena dari wawancara sebelumnya oleh peneliti, menunjukkan ada beberapa ketidakpuasan pasien, seperti menunggu obat yang lama, kurangnya obat, suasana yang tidak nyaman dan lainnya. Penelitian ini bertujuan untuk menganalisis kepuasan pasien klinik kesehatan kulit dan kelamin terhadap pelayanan farmasi berdasarkan perspektif pasien dan petugas kesehatan di RSUD Dr.R.M.Djoelham Binjai. Penelitian ini merupakan penelitian deskriptif dengan pendekatan kualitatif, dimana pengumpulan data menggunakan teknik observasi, wawancara, catatan lapangan dan dokumentasi. Responden sebanyak 10 informan yang terdiri dari, 4 informan dari pasien yang berulang berobat jalan ke klinik kesehatan kulit dan kelamin, 2 informan dari dokter , 2 informan dari pelayanan farmasi/apoteker dan 2 informan dari manajemen rumah sakit. Hasil wawancara pada penelitian ini menunjukkan pasien merasa tidak puas dengan pelayanan instalasi farmasi di RSUD Dr.R.M.Djoelham Binjai. Manajemen pengelolaan sediaan farmasi dan farmasi klinik (sarana dan prasarana) harus ditingkatkan dan menambah petugas pelayanan farmasi pada RSUD Dr.R.M.Djoelham Binjai agar pasien menjadi puas.
The Use of Non-specific Anti-inflammatory Drugs (Dicloberl) in Patients with Chronic Non-specific Prostatitis
Authors: Ю. М. Гурженко  , В. В. Спиридоненко
Published: December 2019

The positive experience of using Dicloberl suppositories in 126 patients with chronic nonspecific prostatitis is shown. Its high clinical (93.7%) and bacteriological (91.3%) effectiveness was established. The drug is well tolerated, has minimal side effects (4.7%).
Biological Therapy of Patients with Hypersexuality
Authors: Г. С. Кочарян
Published: December 2019

The article notes that hypersexuality can be eliminated with successful therapy of the pathology that led to its appearance, as well as the need to treat concomitant pathological mental conditions that can directly or indirectly affect problematic sexual behavior. Medications of various groups that are used to eliminate hypersexuality are presented: selective serotonin reuptake inhibitors, tricyclic antidepressants, opiate receptor blockers, antiepileptic drugs, tranquilizers, antipsychotics, cholinesterase inhibitor rivastigmine, estrogens, analogues of gonadotropin releasing hormone, normotonic lithium carbonate and etc., as well as some recommendations for the management of patients with Parkinson’s disease in whom hypersexuality resulted from the use of dopaminergic drugs. Cases of the use of electroconvulsive therapy and deep brain stimulation in this pathology are submitted.
Prospects for the Use of Indole-3-carbinol in the Treatment of Benign Prostatic Hyperplasia
Authors: Ю. М. Гурженко  , В. В. Спиридоненко
Published: December 2019

The objective: to establish the possibility of the effect of indole-3-carbinol on the inflammatory component in men with benign prostatic hyperplasia by assessing symptoms before and after treatment.Materials and methods. The Institute of Sexology and Andrology LLC observed 142 male patients with BPH I degree, which were divided into three clinical groups. Group I included patients (n=39) who received a combination of I3C extract (Invitol) and Тamsulosin 0,4 mg/day; the second – patients (n=71) who received standard therapy, with the inclusion of Тamsulosin 0,4 mg/day; in III – (n=32) persons who did not receive treatment at all. The control group consisted of 30 healthy men. Invitol was prescribed in a dose of 1 capsule twice a day. After eating for 12 weeks, Тamsulosin at a dose of 0,4 mg/day once in the morning after eating for 12 weeks. The age of patients ranged from 50,2 to 62,5 years, on average – 56,2±3,2 years. The duration of the disease is from 3,5 to 7 years (on average 5,5±0,8 years). Before and during the treatment, all patients underwent traditional examinations.Results. Based on the results of examinations in patients with BPH who received conservative therapy, it follows that: the concomitant inflammatory process in the tissues of the prostate gland requires the use of pathogenetic agents, which include natural catechin – indole-3-carbinol in combination with selective α-blocker; the combination of Invitol Invitol and tamsulosin prescribed to patients contributed to a significant decrease in leukocyturia levels by 5,1 times and bacteriuria by 7,1 times (p<0,001) than traditional tamsulosin monotherapy.Conclusion. The combination of Invitol and tamsulosin creates the conditions for a faster recovery of IPSS and QoL in people with BPH than traditional tamsulisin monotherapy.
A Pathological Sexual Stereotype in the Form of the Absence of Sexual Desire Towards the Wife, Coital Anejaculation and Anorgasmia: а Clinical Case
Authors: Г. С. Кочарян
Published: December 2019

The article reports about possible negative effects of masturbation combined with pornography that may result in formation of pathological sexual stereotypes, whose particular manifestation consists in a decrease of sexual activity in married life and a reduction of sexual desire towards the wife. A clinical case is described, where a 35-year-old male after a certain age switched over to a regular masturbation, which was carried out with use of classical heterosexual internet porn, and sharply reduced the rate of sexual contacts with his wife (almost absolutely withdrew from them), as sexual desire towards her was actually absent, and ejaculation and orgasm during coituses did not occur. The patient was given hypnosuggestive therapy in the variant of directive programming with cognitive influences aimed to explain the mechanism of appearance of the sexual disorder, inadequacy of the patient’s behaviour and its negative effect on relationships in the married life as well as on the ability of his wife to get pregnant and deliver a child (the mutual dersei of the spouses). The above treatment resulted in full recovery: the sexual desire towards the wife reached to 100%, ejaculation and orgasm occurred during all coituses.
Results of a Continent of Urine After an Open Retropubic Prostatectomy with Preservation of the Puboprostatic Ligament
Authors: С. В. Головко  , А. А. Кобірніченко
Published: December 2019

Open retropubic prostatectomy is one of the most common operations used to treat clinically localized prostate cancer (PCa). Today, there is a limited amount of evidence of the successful use of some modern surgical modifications.The objective: to analyze the functional results of applying the technique of preservation of the prostoprostatic ligament in a group of patients with localized prostate cancer.Materials and methods. A clinical retrospective study was carried out over a 3-year period at the Urology Clinic of theScientificCenter for the Management of Human Migration. The study included men with clinically localized prostate cancer who agreed to undergo surgical treatment. Patients with locally advanced forms of prostate cancer and those with severe concomitant pathology were excluded from the study. Data analysis was performed using SPSS software (version 17).Results. In total, from September 2014 to September 2017, 72 patients underwent open-ended radial prostatectomy with preservation of the puboprostatic ligament. The average age of the patients was 67 years (ranged from 55 to 76 years). In 6 patients, stress incontinence was detected, in 8 patients, post-prostatectomy incontinence was detected for 3 months. So, 58 (out of 72) patients out of 72 for 3 months were continental.Conclusion. Preservation of puboprostatic ligaments when performing an open-ended posterior prostatectomy is associated with faster and more frequent renewal of the urine continent in patients with clinically localized prostate cancer.
Neuroimaging Characteristic of Structural Disorders of the Brain and Cerebrospinal Fluid Spaces in Patients with Chronic Cerebral Ischemia
Authors: О. А. Росицька
Published: December 2019

The objective: to evaluate the neuroimaging markers of structural disorders of the brain and cerebrospinal fluid spaces in patients with chronic cerebral ischemia (CHEM) on the background of multifocal atherosclerosis.Materials and methods. The study enrolled 137 patients aged 40 to 84 years with chemotherapy with multifocal atherosclerosis. Patients were divided into three clinical groups depending on the localization of vascular pool lesions with stenosing atherosclerosis. Patients underwent qualitative and quantitative assessment of focal and diffuse changes in the substance of the brain and cerebrospinal fluid spaces.Results. According to the frequency of detection among structural changes in the brain in patients with different variants of the combination of vascular pools affected by atherosclerosis, mild leukoaraiosis (61.3% from 97.1%) and mixed cerebral atrophy (74.5%) prevailed. Lacunar focal changes in CHEM were found in half of the cases (51.8%), including in the clinical group I in 36.7% of cases, in the second group in 56.3%, in the III group in 55.0 % Single lacunar foci in the general group of patients prevailed over numerous 2.7 times (37.9% versus 13.9%; p<0.001). More often, lacunar foci were territorially cortical (in 24.1% of cases) than subcortical (in 2.9% of cases; p <0.001). Most patients with CHM have found a combination of several MR markers of structural brain damage.Conclusion. In patients of all age groups with chronic cerebral ischemia (CHEM), structural brain lesions were established based on the determination of various MR markers: white matter hypertension (leukoaraiosis – 97.1%), cerebral atrophy (74.4%), lacunar infarction (51, 8%), territorial postinfarction foci (56.2%). The multifocal nature of vascular lesion, comorbidity, and multifactoriality affect the heterogeneity and severity of structural brain disorders that determine the course of chemotherapy.
Simulation Technologies in Training of Family Drivers
Authors: В. М. Ждан  , М. Ю. Бабаніна  , Є. М. Кітура  , М. В. Ткаченко  , Л. М. Шилкіна  , О. А. Кир’ян
Published: December 2019

The objective: feasibility of introducing simulation technologies into the educational process of interns and cadets-doctors in the specialty «General Practice – Family Medicine».Materials and methods. The article presents the experience of applying the system of Body Interact – clinical clinical education, the educational program of virtual clinical scenarios at the Department of Family Medicine and Therapy, which allows to recreate a certain clinical situation with all necessary modern set of objective, laboratory and instrumental methods of examination and conduct treatment in accordance with modern protocols of European and American medical associations in real time.Results. The simulation training technologies implement more effective practical training of doctors on specialty «General practice – family medicine», improving the effectiveness of training in 2–3 times.Conclusions. The using of interactive techniques, including the «Virtual Patient», in the professional training of family doctors, allows to solve the problem situations through effective actions, intuition, training, and the development of communicative skills.
Primary Health Care in the World: Results of the 40-year Implementation of the Almaty Declaration (1978) and Future Development According to the Astana Declaration (2018)
Authors: В. І. Ткаченко
Published: December 2019

The article presents the results of the development of primary health care from the aprovement of the Almaty Declaration in 1978 to the signing of the Astana Declaration of 2018. It is emphasized that despite the actions taken, the pace of development and strengthening of primary health care is unsatisfactory, which is confirmed by numerous reports. According to reports of World Health Organization 50% of the world’s population still partially or completely do not have access to basic medical services, including treatment and prevention of infectional and non-communicable diseases, reproductive health, protection of women and children’s health. Taken into accaunt the current situation, WHO held the Global Conference on Primary Health Care, where the reports from world leaders and ministries on this issue were represented. The article discribes the generalized results in the development of primary care in the world according to the submitted reports. It is emphasized that in some countries today, the levels, rates of development of PHC and its financing are insufficient. Patients are forced to pay for basic medical services from their own funds. The negative consequences of paying for services from one’s own funds are felt by more people than 15 years ago. About 925 million people spend more than 10% of the income on medical care, and 200 million spend more than 25% of their income on it. At the same time, indicators of impoverishment as a result of payment for medical care increased among all groups of the population, except the extremely poor. WHO sets one of the global health goals for all countries to increase the cost of primary health care by at least 1% of its gross domestic product .The specified goals, principles and objectives of the PHC that WHO sets for the future are detailed. The full text of the Astana Declaration 2018 is given. The role and participation of the World Association of Family Doctors (Wonca) and Ukraine are described. In general, primary health care has been and will be at the forefront of the world’s health systems priorities, its further development and strengthening is a priority task posed by the World Health Organization for all countries of the world, which will lead to the protection and strengthening of the health of all people, the formation of effective affordable health care for all.
POETICS OF A. KRIVOSHAPKIN’S PROSE
Authors: Vinokurova Antonina Afanas'evna , Okorokova Varvara Borisovna
Published: December 2019

The article examines the contribution of the national writer of Yakutia A. V. Krivoshapkin to the development of the Even prose and the Northern peoples’ literatures on the whole. A. Krivoshapkin is a prominent prose writer, author of historical, social-psychological and philosophical novels. The writer aims to describe the life of his compatriots and to reconstruct their history. Ethnographism, folklorism and historicism of his works constitute the originality of the Even novel. It is shown that the novelist reconstructs the Even national character, psychologically convincingly reveals the image of a modern human.
POETICS OF V. N. LEONTYEV’S LITERARY-CRITICAL ARTICLES
Authors: Grigor'eva Lyudmila Pavlovna , Gladkina Ekaterina Fedorovna
Published: December 2019

The article is devoted to studying the poetics of literary-critical works of one of the first Yakut literary critics Vasiliy Nikanorovich Leontyev (1895-1932). The paper focuses on analysing the storyline and compositional structure of the literary-critical articles and identifying the author’s techniques to influence the readers. The conclusion is made that poetics of V. N. Leontyev’s literary-critical works is based on three key functional features of literary criticism: dialogic relation with its subject - literature, application of rhetoric techniques and focus on modernity.
SPECIFICITY OF AUTHOR’S REALIZATION OF INTER-GENRE FORMS IN THE YAKUT POETRY OF THE SECOND HALF OF THE XX CENTURY (BY THE MATERIAL OF I. GOGOLEV’S AND S. TARASOV’S WORKS)
Authors: Efremova Ekaterina Mikhailovna , Posel'skaya Viktoriya Dmitrievna
Published: December 2019

The article analyses “The Song of the Lena” by I. Gogolev and “A Handful of Fireplace Ash” by S. Tarasov from the viewpoint of specific meta-genre structures, genre synthesis: architectonics, motive-figurative complex, structural and compositional arrangement, etc. New methodological approaches allow considering these poetical works as “samples” of a book of poems (montage polycyclic structure, final book). Special attention is paid to the systemic and typological approach to studying such a literary form as a book of poems in the Yakut poetry of the second half of the XX century. It’s a cardinally new approach to analysing a lyrical text in the Yakut literary criticism.
PROBLEMS OF THE ARABIC WOMEN IN THE NOVEL “GIRLS OF RIYADH” BY RAJAA ALSANEA
Authors: Vavichkina Tat'yana Anatol'evna , Vlasova Yuliya Evgen'evna
Published: December 2019

The article analyses the feminist novel by the modern Saudi authoress Rajaa Alsanea “Girls of Riyadh” revealing the problem of gender relations in the Middle East. The novel, severely criticized by the Saudi conservatives and highly appreciated by progressive public opinion, is analysed at the genre, thematic and problematic levels. It is shown that the authoress criticizes the Muslims’ sluggishness, raises some topical problems (inequality of men and women in Saudi Arabia, women’s unfreedom when choosing career, husband, clothes) and logically concludes that the patriarchal Saudi society should change.
SEMANTIC CHANGES IN VOCABULARY OF PRIVATE EDUCATION SPHERE
Authors: Gataullina Alsu Gaisovna , Zalyalova Regina Renatovna
Published: December 2019

The article is devoted to describing semantic peculiarities of the lexemes functioning in the sphere of the modern Russian education. Using the material of the Russian language dictionaries and the Russian National Corpus, the authors trace the origin of the lexemes functioning in the sphere of private education (family tutor, governess, tutoring, mentor, tutorial, coaching). The paper describes the peculiarities of their functioning in the Russian language, considers compatibility properties and identifies the trends of their semantic development.
GENDER DISCOURSE: SPECIFICITY OF SPEECH TACTICS OF A FEMALE LINGUISTIC PERSONALITY (BY THE MATERIAL OF M. K. ANISIMKOVA’S NOVEL “THE CRY OF THE LOON”)
Authors: Dolzhenko Nataliya Grigor'evna , Sivkova Natal'ya Sergeevna
Published: December 2019

The article analyses gender discourse in order to identify the specificity of speech tactics of a female linguistic personality. Relevance of the study is conditioned by the fact that the authors refer to regional material: the analysis is conducted on the basis of the historical novel of the famous Yugra writer M. K. Anisimkova “The Cry of the Loon”. Originality of the research lies in the fact that the emphasis is made on grammatical forms; peculiarities of speech behaviour are considered through the lenses of formal indicators and lexemes’ grammatical meanings. The analysis of the linguistic material shows that women’s speech has its own lexical and grammatical peculiarities.
FUNCTIONAL AND STYLISTIC PECULIARITIES OF USING ASYNDETIC COMPOUND SENTENCES IN THE MODERN MARI LANGUAGE
Authors: Sokolova Galina Leonidovna , Kolyago Anna Leonidovna
Published: December 2019

The article examines asyndetic compound sentences in the Mari language from the viewpoint of their stylistic usage. Asyndetic compound sentences in the Mari language are similar in structure to the Finno-Ugric ancestor language and serve to express a complicated thought. The analysis of theoretical and factual material shows that asyndetic compound sentences are widely used both in conversational and in bookish speech, though conversational usage prevails. The stylistic potential of asyndetic compound sentences manifests itself most clearly in the literary language.
QUASI-EGOCENTRISM AS A TECHNIQUE OF COMMUNICATIVE-SPEECH ARRANGEMENT OF NORMATIVE TEXT (BY THE EXAMPLE OF NORMATIVE TEXTS OF THE GERMAN PRIMARY SCHOOLS)
Authors: Bol'shakova Tat'yana Mikhailovna
Published: December 2019

The article is devoted to analysing quasi-egocentrism as a special pragmatic technique to construct normative texts addressed basically to the German primary school pupils. Multilevel linguistic means serve as markers of addressers’ egocentric position. The paper concludes that egocentric markedness indicates actualization of the pragmatic nucleus “quasi-addresser” whose introduction into the text seems important to facilitate an addressee’s self-identification with the subject of normative action.
ROLE OF PERSONAL NAME IN DICTEME STYLIZATION (BY THE MATERIAL OF W. MORRIS’S NOVEL “A TALE OF THE HOUSE OF THE WOLFINGS”)
Authors: Noskova Anna Ivanovna
Published: December 2019

The article examines the style-formative potential of a personal name as a nuclear constituent of the dicteme semantic field. It is shown that in W. Morris’s historical novel glorifying Anglo-Saxon England, a personal name actualizes the aspect of the dicteme stylization. Functional orientation of a personal name determines the theme of the dicteme itself and the whole text. Moreover, broadening its semantics towards speech figurativeness, a personal name allows developing the dicteme concept on the basis of correlation of its overall theme and the meaningful content of its notional components.
PERCEPTION OF F. M. DOSTOEVSKY IN PUBLICISM OF THE FAR EASTERN EMIGRATION
Authors: Struk Anna Andreevna
Published: December 2019

The article introduces rare and archival materials on F. Dostoevsky’s personality and creative work published in the Russian émigré periodicals in Harbin (China) into scientific use. The paper aims to identify the specificity of perceiving F. M. Dostoevsky’s personality and creative work in the Russian émigré community in China. Among the basic tendencies in the perception of Dostoevsky’s personality and creative work in the Russian émigré community in China, the author identifies the following ones: attempts to reveal the essence of Dostoevsky’s “Russian idea”, accent on “meaningful aesthetics” when interpreting the writer’s works, appeal to Dostoevsky’s authority in ideological polemics with the Soviet opponents.
SYNONYMY OF PHONETIC TERMS IN THE FRENCH LANGUAGE
Authors: Lukina Ol'ga Ivanovna
Published: December 2019

The article is devoted to studying terminological synonymy in the terminological system of the French language phonetics. The existing viewpoints on this semantic process are presented. The paper suggests differentiating variability and synonymy, which are considered as autonomous processes. The author sticks to the opinion that synonymy of terms is a natural phenomenon with its own peculiarities. The analysis has allowed identifying the following basic types of synonyms: synonyms which describe certain features of one and the same invariant significate and terms-doublets (full synonyms). Structural peculiarities of synonymous phonetic terms in the French language are examined.