bluuebunny/crossref_metadata_2025 huggingface dataset:
Modern Project Management for Successful Execution of Investment Strategy
Authors: Chee Chan Kah
Published: July 2023

In light of the COVID-19 pandemic that shook the world, both multinational enterprises (MNEs) and small and medium enterprises (SMEs) have to learn and manage faster, better, and smarter to stay sustainable and remain competitive. This chapter emphasizes the need for a rethought, reimagined, redesigned, reinvented, reengineered, and rejuvenated waterfall approach in managing predictive projects to modern project management, using the six As in design thinking, to meet the clarion call with an agile mindset.
Maintaining Global Competitiveness Even in a Period of Global Crisis
Authors: Dubrovski Drago
Published: July 2023

In the context of the intense, extensive, radical, and dynamic changes that occur during global crises, strategic management needs to find such development solutions that will enable a company to do its best in such a turbulent environment and maintain or even improve global competitiveness. Deglobalisation and de-internationalisation for businesses in smaller economies can only be temporary, because strategic management in these companies must develop new means and ways to achieve a successful business in such a situation. Therefore, the key task of strategic management is to create a business model. A simplified correlation study between the largest Slovenian companies and major exporters shows the strong export orientation of Slovenian companies even during the COVID-19 pandemic.
Productive-Technological Capabilities, Development, and National Sovereignty
Authors: Araujo Eliane , Peres Samuel Costa
Published: July 2023

This chapter analyzes the industrial and technological capabilities of Brazil in the context of the social and economic losses caused by the COVID-19 global health crisis, and to what extent these capabilities highlight the need to rethink industrial and sciences, technology, and innovation (ST&I) policies in search of greater resilience to future crises, of an external insertion compatible with national sovereignty, and of better prospects for economic development. The evolution of Brazil's production-trade structure is explored, with emphasis on the health complex, followed by a discussion on the perspectives for economic development from the integration into global value chains and on the Brazilian technological and scientific capabilities in a comparative perspective. It concludes that the current crisis has exposed the ongoing process of weakening capabilities of Brazil and the urgency of intelligent and effective designs of industrial and ST&I policies, in a systemic, multidisciplinary, and multisectoral approach.
Exploring the Antecedents of Entrepreneurial Intention With the Theory of Planned Behaviour on Tunisian University Students
Authors: Nasri Wadie
Published: July 2023

This study proposes to use the theory of planned behaviour to predict students' entrepreneurial intentions in Tunisian context. A questionnaire-based survey was conducted to collect responses from 257 students. Regressions analysis was used to test hypotheses. The result shows that attitude, perceived behavior control, and subjective norms significantly influence the entrepreneurial intention. The findings will be useful for government to support entrepreneurship and encourage graduates to start their own businesses to solve even part of the unemployment problem among the youths. The article is one of the initial attempts in Tunisian context to understand the entrepreneurial intention by using the theory of planned behaviour.
Engineering the Interactions of Classical Cadherin Cell–Cell Adhesion Proteins
Authors: Sivasankar Sanjeevi , Xie Bin
Published: July 2023

Classical cadherins are calcium-dependent cell–cell adhesion proteins that play key roles in the formation and maintenance of tissues. Deficiencies in cadherin adhesion are hallmarks of numerous cancers. In this article, we review recent biophysical studies on the regulation of cadherin structure and adhesion. We begin by reviewing distinct cadherin binding conformations, their biophysical properties, and their response to mechanical stimuli. We then describe biophysical guidelines for engineering Abs that can regulate adhesion by either stabilizing or destabilizing cadherin interactions. Finally, we review molecular mechanisms by which cytoplasmic proteins regulate the conformation of cadherin extracellular regions from the inside out.
The Energetic Landscape of Catch Bonds in TCR Interfaces
Authors: Ayres Cory M , Corcelli Steve A , Baker Brian M
Published: July 2023

Recognition of peptide/MHC complexes by αβ TCRs has traditionally been viewed through the lens of conventional receptor–ligand theory. Recent work, however, has shown that TCR recognition and T cell signaling can be profoundly influenced and tuned by mechanical forces. One outcome of applied force is the catch bond, where TCR dissociation rates decrease (half-lives increase) when limited force is applied. Although catch bond behavior is believed to be widespread in biology, its counterintuitive nature coupled with the difficulties of describing mechanisms at the structural level have resulted in considerable mystique. In this review, we demonstrate that viewing catch bonds through the lens of energy landscapes, barriers, and the ensuing reaction rates can help demystify catch bonding and provide a foundation on which atomic-level TCR catch bond mechanisms can be built.
What’s the Catch? The Significance of Catch Bonds in T Cell Activation
Authors: Faust Michael A , Rasé Viva J , Lamb Tracey J , Evavold Brian D
Published: July 2023

One of the main goals in T cell biology has been to investigate how TCR recognition of peptide:MHC (pMHC) determines T cell phenotype and fate. Ag recognition is required to facilitate survival, expansion, and effector function of T cells. Historically, TCR affinity for pMHC has been used as a predictor for T cell fate and responsiveness, but there have now been several examples of nonfunctional high-affinity clones and low-affinity highly functional clones. Recently, more attention has been paid to the TCR being a mechanoreceptor where the key biophysical determinant is TCR bond lifetime under force. As outlined in this review, the fundamental parameters between the TCR and pMHC that control Ag recognition and T cell triggering are affinity, bond lifetime, and the amount of force at which the peak lifetime occurs.
Clinical features and genetic biomarkers associated with different phenotypes of systemic lupus erythematosus in Paraguayan patients
Authors: Acosta-Colman I. , Morel Z. , Ayala Lugo A. , Jolly V. , De Guillén I. , Langjahr P. , Vazquez M. , Martínez de Filártiga M.T , Acosta M.E.
Published: July 2023

Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by a heterogeneous clinical picture that makes the diagnosis and follow-up of these patients difficult. This study aimed to identify correlations between clinical, immunological, and genetic biomarkers and clinical manifestations in SLE. A retrospective study of data from medical records and immunological and genetic studies of SLE patients in Paraguay was carried out. A descriptive analysis was performed based on the type of variable. Human leukocyte antigen (HLA) allele frequencies (DPA1, DPB1, DQA1, DQB1, and DRB1) were calculated, and univariate logistic regression analyses were performed between each of the explanatory variables and the presence or absence of each phenotype. Odds ratios, 95% confidence intervals, and p values were recorded. Associations with p<0.05 were considered statistically significant. 104 SLE patients were included: 86% were female, with a mean age of 32.80±10.36 years. An association was identified between anti-double stranded DNA (anti-dsDNA) and the presence of the renal phenotype and between anti-dsDNA and the absence of the joint and hematological phenotypes. Immunoglobulin M isotype rheumatoid factor was associated with the absence of a renal phenotype. HLA-DQB1*02:02 and HLA-DRB1*07:01 were associated with the cutaneous phenotype. An association was identified between age at disease onset over 30 years and the presence of the joint phenotype. No other associations were identified. Potential clinical, immunological, and genetic biomarkers of phenotypes have been identified in SLE Paraguayan patients.
Secondary School Athletic Trainers’ Perceptions of the Influence of Social Determinants of Health and Socioeconomic Status on Clinical Management Decisions
Authors: Hernandez Mayrena Isamar , Miller Elena Catherine , Biese Kevin M. , Columna Luis , Andreae Susan , McGuine Timothy A. , Snedden Traci R. , Eberman Lindsey E. , Bell David Robert
Published: July 2023

Context

Evidence suggests that lower socioeconomic status (SES) and negative social determinants of health (SDOH) contribute to health care disparities. Due to their accessibility in the high school setting, secondary school athletic trainers (SSATs) may encounter patients who are historically underserved in health care, such as patients with low SES. However, a significant gap in knowledge exists regarding how SDOH and SES may influence SSATs’ clinical management decisions.

Objectives

To describe SSATs’ perceptions of how patient SDOH and SES influence clinical management decisions and to identify barriers to athletic health care.

Design

Cross-sectional study.

Setting

Online survey.

Participants or Other Participants

National Athletic Trainers’ Association SSATs (6.7% response rate).

Main Outcome Measure(s)

Secondary school athletic trainers were asked about their perceptions of patient SDOH and SES (content validity index = 0.83 for relevancy). The levels of relevance and agreement were answered on a 4-point Likert scale. Data were summarized using means and SDs, frequencies and proportions (%), and median scores.

Results

A total of 380 SSATs participated (mean years of experience = 14.9 ± 11.7 years). When providing care, most (71.3%) SSATs believed their patients’ health or health care access to be the most relevant of the 5 SDOH, whereas the other 4 SDOH were less than 60% relevant. Most SSATs agreed or strongly agreed that patient SES affected both referral (67.4%) and the reliance on conservative treatment before referral (71.2%). Secondary school athletic trainers identified patient or guardian compliance (70.2%) and type of health insurance (61.5%) as barriers to providing care to patients with low SES.

Conclusions

Secondary school athletic trainers perceived health or health care access as the most relevant social determinant when providing care to patients with low SES. When SSATs further considered the SES of patients, they identified all SDOH as barriers that they were ill equipped to navigate as they delivered care and engaged in patient referral.
Balance Training With Stroboscopic Glasses and Neuromechanics in Patients With Chronic Ankle Instability During a Single-Legged Drop Landing
Authors: Lee Hyunwook , Han Seunguk , Hopkins J. Ty
Published: July 2023

Context

Therapeutic interventions for individuals with chronic ankle instability (CAI) are recommended to improve muscle strength, postural control, and range of motion. However, their effects on neuromechanics during a drop landing remain unclear. In addition, even though therapeutic interventions with stroboscopic glasses appear to effectively improve postural control, how they affect landing neuromechanics remains unclear.

Objective

To identify the effect of balance training with stroboscopic glasses on neuromechanics during a single-legged drop landing in patients with CAI.

Design

Randomized controlled clinical trial.

Setting

Laboratory.

Patients or Other Participants

A total of 50 participants with CAI were randomly assigned to 1 of 2 groups: strobe (n = 25; age = 22 ± 3 years, height = 174.7 ± 8.2 cm, mass = 71.8 ± 12.2 kg) or control (n = 25; age = 21 ± 2 years, height = 173.1 ± 8.3 cm, mass = 71.1 ± 13.5 kg).

Intervention(s)

The 4-week rehabilitation (3 sessions per week) included hop-based tasks and single-legged stance. The strobe group wore stroboscopic glasses during the training, whereas the control group did not.

Main Outcome Measure(s)

Ankle-, knee-, and hip-joint kinematics and 4 lower extremity muscle activations 150 milliseconds before and after initial contact during a single-legged drop landing in the 2 groups.

Results

The strobe group showed greater eversion (from 150 milliseconds before to 30 milliseconds after initial contact) and dorsiflexion (from 30 to 96 milliseconds after initial contact) angles and peroneal longus (from 35 milliseconds before to 5 milliseconds after initial contact) and tibialis anterior (from 0 to 120 milliseconds after initial contact) activation in the posttest than the pretest.

Conclusions

Patients with CAI who underwent a 4-week rehabilitation with stroboscopic glasses demonstrated changes in neuromechanics, including increased ankle-dorsiflexion and -eversion angles and tibialis anterior and peroneus longus activation, during a single-legged drop landing. This finding suggests that use of stroboscopic glasses during rehabilitation could help patients with CAI develop safe landing mechanics.
Metachronous Occurrence of Anal Canal and Cervical Carcinoma: A Rare Case Report
Authors: Akhtar Kafil , Fazal Nuzra , Irfan Sarah , Hussain Bilal
Published: July 2023

ABSTRACT

The occurrence of a second primary cancer in a cancer survivor is well documented. It may be synchronous or metachronous. We present a rare case of a 70-year-old woman who presented with bleeding per rectum and was diagnosed with basosquamous anal carcinoma. Four years later, she presented with complaints of bleeding per vaginam and was then rendered the diagnosis of squamous cell carcinoma of the cervix. Anal cancer has many similarities with cervical cancer: both are epithelial cancers that appear to be caused or closely associated with high-risk human papillomaviruses (HPV) and are frequently adjacent to full-thickness intraepithelial lesions, i.e., anal intraepithelial neoplasia 3 and cervical intraepithelial neoplasia 3, respectively. HPV is a causative agent of anogenital and cervical cancers. Patients treated for a preinvasive or invasive HPV-associated cancer may be at increased risk of a second such malignancy. Since anal canal and cervical cancers share a common etiology, we should consider cervical cancer as a metachronous cancer occurrence in the follow-up of anal canal cancer.
A giant vesical calculus
Authors: Chandrasekaran Gopalakrishnan , Mathirajan Chelian , Pandiarajan Rajasabai
Published: July 2023

Vesical calculi are common in urological practice. However, encountering a giant vesical calculus weighing more than 100 g is rather rare. We report a patient who presented with mild symptoms and was found to have a single giant vesical calculus weighing about 1334 g. Lack of access to basic medical facilities and milder symptoms may be the predisposing factors in this patient for a calculus to enlarge into such abnormal weight.
The value of webinars during COVID-19 pandemic
Authors: Dev Preetham , Thyavihally B. Yuvaraja , Waigankar Santosh Subhash , Agarwal Varun , Pednekar Abhinav P. , Shah Akash
Published: July 2023

Introduction:

An opportunity for e-learning has been created by the ongoing pandemic and lockdown, along with the availability of efficient technology. Webinars have filled in the lacunae of the learning process. We conducted an online survey to evaluate the interest and opinion regarding webinars, which enables for standardization of future webinars and reap the maximum benefits.

Methods:

An online survey was conducted among practicing urologists and urology residents. The survey was formulated and edited by a group of urologists and uro-oncologists who had experience conducting several regional and international conferences and webinars. The survey comprised 39 questions divided into six parts.

Results:

A total of 328 urologists throughout the country participated in the survey, and 303 complete responses were obtained for the analysis. 67.3% subjects felt that live webinars are the preferred method of knowledge exchange during the coronavirus disease pandemic, and 58.1% felt that this concept of webinars had to be extended even after the pandemic was over. Few shortcomings in the webinars included lack of networking (41.3%), lack of personal connection (73.3%), and lack of practical skills (35%). About 85.5% felt that the duration should be <90 min, and 83.2% thought that speakers should be restricted to <5. They were comfortable attending the webinars on weekends (48.8%) or weekdays but after hospital hours (43.9%). Most of them felt (92.4%) that webinars should be focused, covering a single theme and including international and national speakers (84.2%).

Conclusions:

Webinars can be streamlined for the better and continued after the pandemic. A few issues in this novel learning process have to be adequately addressed to strengthen this modality of academic urology.
Comparison of two drainage parameters on diuretic renogram in predicting the fate of prenatally detected pelvi-ureteric junction-like obstruction
Authors: Sharma Gyanendra Ravindra , Sharma Anshu Gyanendra , Sharma Neha Gyanendra
Published: July 2023

Introduction:

In infants with suspected pelviureteric junction (PUJ) like obstruction, we compared the drainage patterns suggested by t 1/2 and normalized residual activity (NORA) to determine which parameter can differentiate obstructive from nonobstructive dilatation and thus predict the need for surgery.

Materials and Methods:

Infants presenting with prenatally detected PUJ-like obstruction from January 2014 to March 2020 were evaluated with ultrasonography. Diuretic renogram was performed using Tc99m ethylene dicysteine using the F0 protocol. Subjects with a differential renal function >40% were included in the study. The t ½ values were noted. NORA was calculated by dividing the tracer values at 60 min with the values at 2 min. The infants were followed using ultrasonography. Renogram was repeated if there was increase in hydronephrosis or after 6 months if hydronephrosis did not regress. The follow-up was continued till a decision for pyeloplasty was made or the hydronephrosis regressed. Pyeloplasty was advised if differential function dropped to below 40%.

Results:

34 patients met the inclusion criteria. NORA and t ½ had very poor concordance in defining the drainage pattern. t ½ values did not correlate with the need for surgery or conservative management (P ≥ 0.05). Good drainage pattern by NORA was associated with regression of hydronephrosis (P ≤ 0.001). NORA predicted obstruction more accurately.

Conclusion:

NORA can define good drainage in a much larger subset of patients with PUJ-like obstruction who eventually do not need surgery. However, further multicenter studies are needed to confirm this.
Development and internal validation of preoperative and postoperative nomograms predicting quadrifecta outcomes following robotic radical prostatectomy
Authors: Sharma Gopal , Darlington Danny , Ahluwalia Puneet , Gautam Gagan
Published: July 2023

Introduction:

Literature on the factors predicting functional and oncological outcomes following robot-assisted radical prostatectomy (RARP) is sparse for the Indian population. Hence, the primary objective of this study was to develop preoperative and postoperative nomograms predicting these outcomes in patients with prostate cancer undergoing RARP.

Methods:

This retrospective analysis identified the predictors of quadrifecta outcomes, i.e., the patients who did not have complications, were continent, had negative surgical margins, and were biochemical recurrence free with at least 1 year of follow-up following RARP. We excluded the return of sexual potency as the majority of the patients in our series were sexually inactive preoperatively. We used the backward stepwise logistic regression analysis method to identify the predictors of quadrifecta. Preoperative and postoperative nomograms using these predictors were developed and validated with bootstrapping, goodness of fit, calibration plot, decision curve analysis (DCA), and theits receiver operating characteristic (ROC) analysis.

Results:

Of the 688 patients who underwent RARP, 399 were included in this study, and 123 (30.8%) of these achieved the quadrifecta outcomes. Preoperative nomogram was developed using four variables, i.e., prostate-specific antigen (PSA), Charlson Comorbidity Index (CCI), biopsy Gleason score, and clinical stage. Postoperative nomogram included PSA, CCI, pathological tumor stage, tumor grade, and positive lymph node. Both the models were internally valid on bootstrapping, calibration plots, and goodness of fit. On the ROC analysis, preoperative and postoperative nomograms had an area under the curve of 0.71 and 0.79, respectively. On the DCA, at a threshold probability of 5%, both the models showed a net benefit.

Conclusions:

We developed and validated accurate nomograms for predicting quadrifecta outcomes following RARP for the Indian population.
Association of human papillomavirus in penile cancer
Authors: Sharma Prashant Kumar , Panaiyadiyan Sridhar , Kurra Santosh , Kumar Raman , Nayak Brusabhanu , Kaushal Seema , Sharma Alpana , Kumar Rajeev , Seth Amlesh , Singh Prabhjot
Published: July 2023

Introduction:

Human papillomavirus (HPV) is a known risk factor of penile cancer (PeCa). However, studies evaluating its true association are limited. In this study, we aimed to estimate HPV prevalence and its true association with PeCa in terms of molecular biological activities.

Materials and Methods:

This single-institutional prospective observational study was conducted between June 2016 and August 2019. We included 40 men with PeCa as a study group and 20 age-matched uncircumcised men who underwent circumcision for phimosis as a control group. Both the groups underwent deoxyribonucleic acid isolation for HPV subtyping followed by evaluation of relative E6/E7 messenger ribonucleic acid (mRNA) expression profile and relative telomerase activity in tissue samples. HPV-16 and -18 were categorized as high-risk, whereas HPV-6 and -11 were categorized as low-risk subtypes.

Results:

The mean (±standard deviation) age of PeCa was 51 ± 15.9 years. The majority of patients had stage II disease, and the most common procedure done was partial penectomy. The overall prevalence of HPV in PeCa was 42.5% (n = 17) as compared to 20% (n = 4) in controls. Among the subtypes, the most common subtype was HPV-16 noted in 33.3% (8/24) of cases, followed by HPV-18 in 29.2% (7/24) of cases. PeCa tissues had a significantly higher relative E7 mRNA expression for HPV-18 than the control group (P = 0.016). The mean relative telomerase activity was significantly higher in the PeCa tissues than the control group (138.66 vs. 14.46, P < 0.001). A significantly higher relative telomerase activity was noted in the PeCa tissues positive for high-risk HPV subtypes than controls (141.90 vs. 14.46, P = 0.0008), but not between high-risk HPV-positive and HPV-negative PeCa cases (141.90 vs. 137.03, P = 0.79). High-risk subtypes were not associated with tumor stage (P = 0.76) or lymph node metastasis (P = 0.816).

Conclusions:

HPV was associated in 42.5% of PeCa cases based on our experience from a single institution. PeCa tissues had a higher relative E7 mRNA expression for HPV-18 and relative telomerase activity as compared to controls suggesting their potential role as surrogate markers of virus-induced tumorigenesis.
Metastatic epithelioid trophoblastic tumor in retroperitoneal nodes in a case of regressed germ cell tumor of testis
Authors: Sakhadeo Uma , Menon Santosh , Prakash Gagan , Desai Sangeeta B.
Published: July 2023

Epithelioid trophoblastic tumor is an extremely rare tumor which occurs in women of the reproductive age group following a previous gestation. Its occurrence in male patients is remarkably rare, with only six cases reported in the English literature. Herein, we discuss the unusual occurrence of this tumor in a 31-years-old male patient as a component of non-seminomatous germ cell tumor. It presented as retroperitoneal metastasis with associated testicular microlithiasis (regressed germ cell tumor).
Latin American research on cardiovascular diseases: A bibliometric-network approach
Authors: Espíritu-Martínez Antony Paul , Romero-Carazas Rafael , Mamani-Jilaja Dometila , FLores-Chambilla Salvador Gerardo , Espinoza-Véliz Miriam Zulema , Espinoza-Egoavil Melvi Janett , Gomez-Perez Katerine Karen , Espinoza-Véliz Karina Liliana , Carpio-Delgado Fabrizio Del , Quesada Tania Quiroz
Published: July 2023

The increase in the global prevalence of cardiovascular diseases has raised great concern among health professionals worldwide, making the advancement of knowledge in this field even more important. The aim of the study was to perform a bibliometric analysis of the scientific literature in Latin America on cardiovascular pathologies from 2003 to 2023. The methodology was based on a bibliometric and quantitative analysis of the literature. The scientific production indicators were generated from 6660 documents selected from Scopus using keywords in English ("diseases" and "pathologies"). The number of publications devoted to the subject increased by 89% between 2009 and 2022. Brazil is the country with the highest scientific production (63.9%), and the Universidade de São Paulo with the most publications (n=1277). The journal Arquivos Brasileiros de Cardiologia had 684 publications, with Lotufo, P.A. (n=60) being the author with the most papers. It is concluded that cardiovascular diseases are important, as they are the main cause of disability and premature death, and both have an impact on increasing the cost of medical care. As a consequence, there has been an increase in the number of medical studies dedicated to this pathology in Latin America and the rest of the world.
Etiology of Acute Infectious Meningitis and Meningoencephalitis in Karachi, Pakistan: Retrospective Observational Study from a Tertiary Care Center
Authors: Shakoor Sadia , Fatima Tazeen , Mir Fatima , Shahid Asima , Shaheen Najma , Khan Erum , Jamil Bushra
Published: July 2023

Meningoencephalitis (ME) is potentially fatal and is caused by a wide array of pathogens. Diagnostic and health-care access gaps prevent accurate estimation of the pathogen-specific burden in low-resource settings. We present pathogen-specific etiologies among patients hospitalized with ME in Karachi, Pakistan. We performed a retrospective hospital database evaluation of pathogen etiology and outcomes of community-acquired infectious ME at a single tertiary care center in Karachi, Pakistan. Annual rates of hospitalization (ARH) were calculated by adjusting for missed cases and are reported per 100,000 population. From May 2017 to April 2020, 522 episodes of infectious ME were identified in 514 patients. The overall ARH from ME was 5.7/100,000 population (95% CI, 5.1–6.1). Among children younger than 5 years, the ARH was 9.8/100,000 population (95% CI, 8.1–11.8). Unknown causes of ME resulted in the greatest burden, with an ARH of 1.9/100,000 population (95% CI, 1.7–2.2). Among known causes, the greatest burden of hospitalizations resulted from tuberculous ME (0.8/100,000; 95% CI, 0.6–0.97), followed by pneumococcal and enteroviral ME (both 0.6/100,000 population; 95% CI, 0.5–0.8). The burden of ME caused by pathogens preventable through vaccination or public health measures outweighed that of ME from other causes (P = 0.0092, Fisher’s exact test). We report a broad range of pathogens causing ME in southern Pakistan and show a high burden of preventable illness. Synergistic actions to improve diagnostic strategies, increase vaccinations, and introduce measures to reduce water-borne and vector-borne diseases are required to reduce the ME burden in Pakistan and prevent future outbreaks.
Seroprevalence of Chagas Disease among People of Latin American Descent Living in Suffolk County, Long Island, New York
Authors: Saldivar Miguel A. , Michelen Yamil E. , Milla Lucia , Kalogeropoulos Andreas P. , Sin Eric , Hellman Harriet L. , Gilman Robert H. , Marcos Luis A.
Published: July 2023

This cross-sectional study estimated a one-time point seroprevalence rate of Chagas disease among people of Latin American descent in Suffolk County, Long Island, New York. Subjects who met the inclusion criteria were screened using the Chagas Detect Plus Rapid Test (InBios, Seattle, WA) with confirmation via Trypanosoma cruzi enzyme immunoassay and T. cruzi immunoblot assay. Administration of a questionnaire regarding demographics and risk factors followed. A seroprevalence rate of 10.74% was found. Identified risk factors included prior residence in a palm leaf house (odds ratio [OR], 10.42; P = 0.003; 95% CI, 2.18–49.76), residence in a house with triatomines (OR, 9.03; P = 0.006; 95% CI, 1.90–42.88), and history of triatomine bite (OR, 9.52; P = 0.009; 95% CI, 1.75–51.77). Our findings emphasize the importance of this frequently underdiagnosed disease and help highlight the importance of early screening among high-risk populations.
Motywy matematyczne na frontyspisach siedemnastowiecznego polskiego piśmiennictwa techniczno-wojskowego
Authors: Rodzeń Jacek
Published: July 2023

This article aims to analyze (from autopsy) mathematical motifs in the frontispieces to selected seventeenth-century Polish technical-military treatises (by Adam Freytag, Kazimierz Siemienowicz and Józef Naronowicz-Naroński). The frontispiece is considered here an iconographic source for the history of science and technology. The rationale for investigating this topic is the process of the progressive mathematization of technical knowledge in Europe in the 15th-18th centuries. It is the first study of this subject with regard to Polish technical-military writing. Only one other article is devoted to this issue (Delphine Schreuder, When Mars Meets Euclid. The Relationship between War and Mathematical Sciences in Frontispecies of Fortification Treatises, 2021), but it does not cover the works of Polish authors. There are also several general studies (mainly in art or architectural history) on frontispieces to fortification treaties (Armin Schlechter, Engraved Title Pages of Fortification Manuals, 2014, Jeroen Goudeau, Harnessed Heroes: Mars, the Title-page, and the Dutch Stadtholders, 2016). The analysis of the typographic compositions of the discussed frontispieces revealed three main motifs: 1. the connection between the art of war and mathematical knowledge, as far as the knowledge of fortification and artillery is concerned; 2. the degree to which those disciplines - both of which combine the practice of the battlefield with theory - were mathematicized; 3. the crucial importance of drafting and measuring instruments for these sciences. The article’s final section addresses the issue of the rhetorical and persuasive function of the frontispieces.
Sprawozdanie Maksymiliana Thulliego z sytuacji w C.K. Szkole Politechnicznej (politechnice) we Lwowie w czasie rosyjskiej okupacji Lwowa w latach 1914–1915
Authors: Rataj Piotr
Published: July 2023

The article presents the translation and edition of the report by Prof. Maksymilian Thullie, the Head of the Imperial-Royal Polytechnic School in Lviv, about the situation at the university during the Russian occupation of Lviv from September 1914 to June 1915. It describes the efforts of professors to preserve the collections and rooms from requisitions and destruction, to obtain livelihoods for employees, and to maintain the functioning of the university in the scope allowed by the invaders.
The Cloud Over the Highway. On the Inescapability of Mystical Experience
Authors: Joas Hans
Published: July 2023

Adam Zagajewski’s essays on poets and poetry are interpreted here in the context of scholarly debates about the specificities of mystical experience. From the four criteria the great American philosopher and psychologist William James developed in 1902, “transiency” and “passivity” can be brought together as indicators of what I call the inescapability of mystical experience, while the two other criteria, namely “ineffability” and “noetic quality”, can be treated as what I call the “paradox of articulation”. The essay demonstrates how profound the reflections of the Polish poet on these questions are, how they are related to his views about the possibilities of contemplation and art in view of the history of violence of the 20th century and what they mean for the future of religion. The highly influential narrative of a world-historical process of ongoing “disenchantment” (Max Weber) loses much of its persuasiveness if these reflections are true.
Little Abysses: Adam Zagajewski’s “Evening, Stary Sącz”
Authors: Warren Rosanna
Published: July 2023

This essay considers Adam Zagajewski’s poem “Evening, Stary Sącz”and in particular, the line “Little abysses open between the stones.”This image invites us to reflect on the many startling gaps and voids in Zagajewski’s poems. At times, those abysses suggest historical and political dimensions particular to Polish (and European) experience in the 20th century; but more often, Zagajewski presents the abyss as moral and metaphysical. “Evening, Stary Sącz,”a poem that doesn’t on its surface appear very threatening, opens suddenly through its “little abysses”into sacrificial reality.
HISTORIA E HISTORICIDAD EN X. ZUBIRI
Authors: Garrido Zaragozá Juan José
Published: July 2023

En el presente ensayo se estudia el tema de la historia y la historicidad en los escritos de la primera etapa (etapa ontológica) del pensamiento de X. Zubiri. Siguiendo las sugerencias de sus maestros Ortega y Gasset y Heidegger, Zubiri aborda esta problemática desde la perspectiva de la reforma del ser, pero ya en este momento apunta una orientación propia que culminará en la etapa de madurez. Frente a la concepción antigua de la historia, la que se hizo presente a partir del siglo xix y que desembocará en las diversas formas de historicismo, Zubiri sostiene que hay que entender el devenir histórico como una dialéctica de posibilidades, por lo que distingue cuidadosamente entre hecho (actualización de potencias) y suceso (actualización de posibilidades), y postula una reforma de la metafísica cuyo programa es: de la naturaleza y de la historia al ser.
CIENCIA Y METAFÍSICA EN CHARLES S. PEIRCE Y ALFRED N. WHITEHEAD
Authors: Nubiola Jaime
Published: July 2023

El objetivo de este artículo es describir con cierto detalle las relaciones efectivas entre Charles S. Peirce y Alfred N. Whitehead, poniendo particular atención en las nociones peirceanas de ciencia y de metafísica, con la convicción de que este contraste puede ayudar a captar mejor el alcance y la hondura del pensamiento de C. S. Peirce.
RADICALIZACIÓN SOCIAL Y SUBCULTURA DE LA VIOLENCIA COMO LEGADO DE ETA LA AGRESIÓN A LA GUARDIA CIVIL EN ALSASUA COMO CASO DE ESTUDIO
Authors: Crespo Alcázar Alfredo
Published: July 2023

la agresión física y verbal propiciada a dos guardias civiles y a sus parejas en Alsasua (Navarra) en octubre de 2016 puso de manifiesto que la subcultura de la violencia difundida y patrocinada por ETA durante sus años de existencia se halla aún presente entre amplios sectores de la sociedad vasca y navarra. Un escenario, por tanto, contrario a los parámetros del normal funcionamiento del Estado de Derecho, cuya principal consecuencia radica en la transformación de las víctimas en victimarios.
CONTRAPOSICIÓN ENTRE ÉTICA Y MORAL EN BAUMAN
Authors: Bravo Álvarez Luis Miguel
Published: July 2023

Zygmunt Bauman, la tarea de construir un nuevo orden para reemplazar al viejo y oxidado actualmente ya no forma parte de ninguna agenda. La modernidad de hoy vive en una continua licuefacción: es la modernidad líquida. Por eso, advertida la dificultad de la tarea –dado que nos enfrentamos a un escenario en permanente transformación– y teniendo en cuenta que las reflexiones de nuestro autor distan mucho de ser una catalogación exhaustiva, el objetivo de este artículo es señalar una distinción primordial: la contraposición entre ética y moral que trasluce en los textos de Zygmunt Bauman. Este contraste es necesario como presupuesto para secundar una aspiración de Bauman: la de hacer de la modernidad líquida un periodo histórico un poco más moral. Además, la relevancia de establecer este contraste se hace manifiesta al adquirir la convicción de que muchas de las ideas de fondo que subyacen detrás de las afirmaciones de Bauman no se nos presentan directamente ante los ojos, sino que han de ser reconstruidas. Por eso, comenzaremos por justificar la importancia de establecer tal distinción, para después ahondar en las nociones que el sociólogo polaco denominaba ética moderna y ética posmoderna, y, a partir de ahí, dilucidar mejor lo que sería para Bauman la moral. Cerraremos nuestro artículo haciendo una valoración de esta perspectiva de Bauman que, como él mismo reconoce, adolece de la misma ingénita incertidumbre del fenómeno analizado.
Chemismus a klasifikace minerálů skupiny tetraedritu z ložisek v Bolívii
Authors: Velebil Dalibor , Hyršl Jaroslav , Sejkora Jiří , Dolníček Zdeněk
Published: July 2023

The quantitative study of chemical composition of ten samples of the tetrahedrite group minerals from six deposits in Bolivia (Animas - Chocaya, Pulacayo, San Vicente, Machacamarca, Cerro Rico, Oruro) provided new data enabling their detailed classification within this group. The majority of samples are usual members of tetrahedrite group: tennantite-(Zn) (San Vicente, Oruro), tetrahedrite-(Zn) (Animas - Chocaya, Pulacayo, San Vicente, Cerro Rico, Oruro) and tetrahedrite-(Fe) (Pulacayo, Machacamarca, Cerro Rico). The recently redefined members of this group - argentotetrahedrite-(Fe) and kenoargentotetrahedrite-(Fe) were found in samples from Cerro Rico and Animas - Chocaya deposits, respectively. The descriptions and quantitative EPMA data for all studied samples are given in the paper.
The Development of Environment-Based Visual Media to Enhance Learning Outcomes and Student Motivation in Science Course
Authors:   Postgraduate Department of Primary Education, Universitas Terbuka, Indonesia & SDN Kotakulon 2, Bondowoso, Indonesia, Ratri Mayarita Lidya , Dafik Dafik ,   Department of Mathematics Education Postgraduate, Universitas Jember, Indonesia, Prastati Trini ,   Postgraduate Department of Primary Education, Universitas Terbuka, Indonesia
Published: July 2023

Learning media plays a crucial role in education, especially in facilitating student understanding and motivation. In this era of rapid technological advancement, learning media has expanded to include various forms such as audio, visual, and multimedia. To enhance learning outcomes, teaching media needs to be utilized as a source of learning for students, including environmental media as a learning resource. Visual media is expected to improve students’ understanding of ecological theme concepts in line with the intended objectives. This study employs the Research and Development (RnD) method in developing learning media, requiring a suitable instructional model that aligns with the content’s characteristics. The ADDIE (Analysis – Design – Development – Implementation – Evaluation) development model is used in developing the Microsoft PowerPoint tutorial video media. Normality tests for the variables were conducted using the Kolmogorov-Smirnov test. Based on the normality test results using SPSS 15 for Windows and the Kolmogorov-Smirnov technique, the values obtained were (0.120), (0.165), (0.114), and (0.127) with significance values of (0.200), (0.092), (0.200), and (0.200) respectively. When the significance level is set at 0.05, the significance values are more significant than 0.05. Subsequently, hypothesis testing (T-test) was conducted to determine the difference in using environment-based visual media between the control and experimental groups using the t-test formula. The t-test formula was used to determine the difference in students’ critical thinking abilities, both in the SPSS 20 for Windows calculation using Separated Variance, as the data exhibited non-homogeneity of variance. The hypothesis testing results indicate that the samples are non-homogeneous, with a calculated t-value of 6.833 and a significance level 0.000. When the significance level is 0.05, the significance value is much smaller than α. Thus, it can be concluded that environment-based visual media influences students’ learning motivation in the Science subject at grade 5 of SDN Kotakulon 2 Bondowoso. Based on the calculation and data analysis, it can be inferred that the hypothesis testing results support Ha (alternative hypothesis) and reject Ho (null hypothesis), meaning there is an influence between the variable (x) of environment-based visual media development and the variable (y) of student learning motivation.
Identifying Human Capital Readiness and Digital Culture toward Employee Performance in Facing Industry 4.0: Case of Pt Perusahaan Listrik Negara Province X
Authors:   School of Business and Management, Bandung Institute of Technology, Indonesia, Anshar Chairul , Ros Bangun Madju Yuni ,   School of Business and Management, Bandung Institute of Technology, Indonesia
Published: July 2023

The emergence of Industry 4.0 has brought changes and challenges to PT Perusahaan Listrik Negara (PLN). In order to adapt and thrive in this new era, it is crucial for companies to identify and enhance their human capital readiness and digital culture toward employee performance. The performance of employees generally has the potential to enhance the productivity of a company in achieving its goals. However, in the process of transforming and improving employee performance in the era of Industry 4.0, PT Perusahaan Listrik Negara (PLN) faces important challenges, namely the lack of mature employee readiness and weak digital capabilities. This study aims to identify the impact of human capital readiness and digital culture on employee performance in the context of facing Industry 4.0. Industry 4.0 represents a significant transformation in the way businesses operate, driven by advancements in digital technology and automation. The study focuses on understanding how the readiness of employees in terms of skills, knowledge, and attitudes, as well as the organizational culture surrounding digital adoption, influence employee performance in the era of Industry 4.0. The research found will be used to determine which dimensions need to be prioritized in order to enhance the “Amount of Work,” “Punctuality,” and “Quality of Work,” aiming to address the company’s shortcomings in both work processes and systems. Based on the analysis, it is found that Soft Skills, Attitude, Digital First Mindset, Flexibility and Agile, and Data Driven Decision Making are the dimensions with the highest priority. These indicators are crucial factors that require improvement. Based on the research found, the proposed programs as company strategies to improve employee performance include enhancing employee capabilities through seminars and workshops related to digital technology. Additionally, improving the company’s technology is essential to enable employees to operate and apply their work digitally.
Violence and Gender Power: A Theoretical Distinction between Violence and Dominance
Authors:   Faculty of Arts and Humanities Hassan II University- Mohammedia- Morocco, Benjelloun Zineb , HassanZrizi HassanZrizi ,   Faculty of Arts and Humanities Hassan II University- Mohammedia- Morocco
Published: July 2023

Violence, dominance and gender power have been often theoretically intertwined for the intricate affinities they hold together. In this paper, we focus on the expression of gender power through violence and other forms of dominance being it verbal, physical or psychological. We mainly aim to provide a theoretical distinction between violence and dominance and how both were academically explored and presented throughout scholarly research in order to clear out any terminological confusion.
Analisando a Alocação de Recursos em Saúde no Município de Itumbiara
Authors: Marque Gomes Ferreira Francisco , Scalon Inácio Igor , Alves Faria Nicolas , Campos Egídio Marco , Pinheiro de Couto Luana , Cristian de Souza Herbert
Published: July 2023

O presente trabalho surge com a necessidade de demonstrar e chamar a atenção da população para alocação dos recursos orçamentários da saúde no município de Itumbiara. Com advento da democratização do acesso a informação, há a necessidade de demonstrar a eficiência na aplicação dos recursos públicos nos serviços prestados pelo governo, pois a analise utilizando parâmetros econômicos de dados oficiais serve para contemplar no orçamento as particularidades vivenciadas por uma população. Pesquisa de corte transversal de dados quantitativos para analise qualitativa, objetivando demonstrar a partir da analise dos dados orçamentário se a gestão dos recursos financeiros atendeu as expectativas observadas após tratamento dos dados em modelo matemático. O presente teve como metodologia a pesquisa bibliográfica como meio de identificar as legislações e normatizações pertinentes e a coleta de dados de saúde no DataSUS. Os dados foram tratados utilizando a inferência estatística e regressão linear, obtendo como resultado um valor de despesa em saúde por habitante para o ano de 2019, próximo ao que foi executado pelo governo municipal. A análise do material produzido oferece condições para propor melhorias na alocação dos recursos, nas Leis Orçamentárias, que são destinados a secretaria municipal de saúde e desenvolver ferramentas para auxiliar os gestores a entender sobre o financiamento desse sistema de tomada de decisões que reflete diretamente na vida das pessoas. A interação dos fatores econômicos em relação a ações realizadas em saúde no município de Itumbiara-GO, pode gerar resultados como redução de gastos e maior eficiência nos serviços prestados a comunidade.
Desafios e oportunidades na gestão de pessoas na construção civil pós-pandemia
Authors: Nunes Alves Jeferson , Fonseca Dias Raphael , Dalava Miranda Marcos , Bruno Silveira Veiga Giordano
Published: July 2023

A construção civil, não só no Brasil, mas em nível mundial, foi afetada consideravelmente no início do confinamento social, recomendado pela Organização Mundial da Saúde (OMS), diante da gravidade e do aumento do número de casos de pessoas infectadas pelo novo Coronavírus, bem como pelo seu poder de transmissão. Muitos empreendimentos e construções precisaram ser paralisados até a obtenção de planos de contingência para o devido funcionamento. A rotina trabalhista mudou, a maneira dos trabalhadores operacionais de se relacionar in loco precisou ser revista e, alguns cuidados sanitários passaram a se tornar imprescindíveis para a retomada das pessoas em seus postos de trabalho. Outro cenário que merece atenção nesse momento é o psicológico dos trabalhadores. O momento provoca uma série de implicações emocionais e sociais. Os riscos envolvidos, a necessidade de mobilização para o enfrentamento da pandemia e a emergência de medidas de prevenção fazem do momento um período delicado, que exige responsabilidade, planejamento, cautela e colaboração. A grande questão é saber como será essa retomada, considerando as adaptações e medidas de segurança necessárias, bem como, aproveitando a oportunidade de inovação e desenvolvimento dos recursos humanos disponíveis. O presente artigo tem por finalidade acompanhar e analisar, de forma sistemática e técnica, como será o gerenciamento das pessoas no setor construtivo, no período de transição pós-pandemia, decorrentes da crise de saúde mundial em face da Covid-19. Contribuindo ainda, com a formação, saúde e qualidade de vida dos trabalhadores da construção civil.