bluuebunny/crossref_metadata_2025 huggingface dataset:
Unilateral Idiopathic Lipid Crystalline Keratopathy: A Clinicopathological Report
Authors: Hasani Hamidreza , Zand Amin
Published: May 2021

Lipid keratopathy refers to corneal lipid infiltrations. We report a 54-year-old female without any systemic disorder presented with a slowly progressive yellow-white infiltrate in the inferotemporal part of the left cornea for six years. Due to a visual axis involvement leading to decreased visual acuity, the patient underwent penetrating keratoplasty on the left eye. The excised corneal button specimen was sent for pathological evaluation. Anterior segment optical coherence tomography (AS-OCT) and confocal scanning microscopy showed an intra-stromal hyper-reflective material consistent with lipid crystalline keratopathy diagnosis. Histopathology revealed an excessive amount of fat droplets in corneal stroma presented as clear areas in hematoxylin and eosin (H & E) staining in keeping with Oil Red O staining. Idiopathic lipid crystalline keratopathy is a diagnosis of exclusion. For such a diagnosis, the serum lipid profile should be checked to rule out fat metabolic disorders and ocular diseases causing chronic inflammation leading to secondary corneal lipid depositions.
Primary Localization of a Hydatid Cyst in the Pancreas via Laparoscopic Treatment: A Case Report
Authors: Hashemi Fard Adeleh , Hoseinpour Deyrestani Hormoz , Golmohamadi Hamed , Rezapanah Alireza
Published: May 2021

Hydatid disease is mainly because of the Echinococcus granulosus at the larval stage. The liver and lung are its most consequences. The pancreatic hydatid cyst (PHC) incidence is very low (0.14%-2%). A 55- year-old female patient presented with epigastric pain for the last one year that the pain did not continue but during one months ago suffered continually. In physical examination, there was not any abdominal bulb, tenderness and rebound tenderness. A 54×59 mm cystic structure was observed by ultrasonography (USG) and Contrast-enhanced Computed Tomography (CT) in the pancreatic body with stone in the gallbladder. Amylase, lipase, and LFT levels were normal. The Anti-hydatid antibody was positive. During laparoscopic exploration, a hydatid cyst was found. Partial cystectomy with external drainage and cholecystectomy was performed once irrigation with scolicidal agent and evacuation of cystic contents was conducted. Histopathological biopsy reported Hydatid cyst. A pancreatic, hepatic cyst is a rare event. Hematogenous is the most common spread way. Cysts in the pancreatic head could be found with obstructive jaundice. Usually, cysts in the body and tail are known to be asymptomatic. USG, CT, and Hydatid serology are useful with the clinical diagnosis as well as monitoring the recurrence. An exploration via surgery is an option that includes pericystectomy, partial cystectomy with/without external drainage or omentopexy, marsupialization, or cysto-enterostomy, which is done. What makes this case unique is the laparoscopic method that we used instead of open surgery, which is a treatment of choice. The recommendation is pre-operative and postoperative antihelminthic (Albendazole). PHC could be present as pseudocyst or cystic neoplasm of the pancreas. For patients with endemic regions and laparoscopic surgery, differential diagnosis of the cystic pancreatic lesion should be noticed. Common surgery approach could be considered for such patients.
Diagnosis of 22q11.2 Deletion Syndrome in a Child With Congenital Heart Disease and Facial Dimorphism: A Case Report
Authors: Moura Carvalho Natalia Dayane , Camargo Ronaldo Castillo , Costa Garcia Heliana Maria , Silva Teles Suely Regina da , Fantin Cleiton
Published: May 2021

22q11.2 deletion syndrome is caused by a deletion in chromosome 22q11.2 and has more than 180 distinct phenotypes; however, no finding is pathognomonic or even mandatory. This syndrome can be diagnosed by fluorescence in situ hybridization. Thus, we report herein a patient from Manaus, Brazil, who has congenital heart disease and facial dimorphism with the presence of 22q11.2 deletion in the N25 region. Male patient, a 1-year-old son of non-consanguineous parents and without a family history of genetic disease. The patient was hospitalized in the cardiac intensive care unit of the Francisca Mendes University Hospital for surgery. The patient was diagnosed with interventricular communication, low atrial implantation, hypertelorism, and macroglossia. The FISH result revealed the presence of a proximal deletion in the N25 region (22q11.2) in only one of the pairs in chromosome 22. This finding revealed a diagnosis of 22q11.2 deletion syndrome, in other words, a hemizygotes deletion with haploinsufficiency of the CLTCL1 gene in this region. However, it is valid to say that the CLTCL1 gene is related to the clinical picture of the patient reported in this study. Cytogenetic analysis was essential for the etiological diagnosis and revealed 22q11.2 deletion in the N25 region, which resulted in 22q11.2 deletion syndrome. The importance of diagnosing this syndrome lies in the best therapeutic conduct, thus allowing a better quality of life for the patient and adequate genetic counseling. Other cytogenetic studies are essential in order to elucidate the size of the deletion and low copy repeats involved in this deletion.
Future of Health Technology Assessment System in Iran: Necessity of Reinforcement in Both Scenarios of Continuation or Relief of Sanctions
Authors: Sarrafkia Ali , Nedjat Saharnaz , Majdzadeh Reza
Published: May 2021

Background: In Iran, health technology assessment (HTA) system dates back to nearly a decades ago (2008).
Objectives: The current study aimed to define steps required to expand HTA in Iran by emphasizing possible future events related to the health sector.
Methods: A preliminary list of future trends potentially influencing Iran’s HTA system was extracted through the literature review. Then, the trends were presented to 12 experts to obtain their opinions. Afterward, their influence on the future of the HTA system in Iran was investigated using in-depth interviews. The interviews were analyzed using the thematic analysis method; Initially, in three categories of capacity building, provision of HTA, and supportive mechanisms, and then according to the essential functions of a health system (i.e., control knobs).
Results: Interviewees believed that strengthening the HTA system is mandatory, regardless of future political events. In the category of capacity building, adjusting training to the needs, using the capacity of graduates in conducting HTAs, training more students in the HTA profession as well as the establishment of a Ph.D. program, turning HTA into public demand, and preventing overuse of medical technologies were elaborated. In the second category (i.e., provision of HTA), the following themes were extracted: modernization and equipping of health system infrastructure based on the evidence provided by HTA, the legitimization of HTA to be used for all health technologies, preventing the introduction of unnecessary technologies and similar technologies that are currently using in Iran, and employing HTA in developing the basic benefit package.
Conclusions: Due to international sanctions, Iran has a niche healthcare market. If sanctions continue, HTA would be a serious necessity to increase the resilience of the health system. In the case of sanctions relief, HTA is still necessary for the optimization of allocating resources. These steps, in both scenarios, are mostly related to the institutionalization of HTA, mostly on the legitimization of HTA and behavioral changes.
Factors Affecting Organization Performance Assessment: A Comprehensive Review
Authors: Janati Ali , Gholizadeh Masoumeh , Hajizadeh Alireza , Bahreini Rona
Published: May 2021

Context: Regular performance assessment is the basis of effective managerial decision-making, which is crucial to increasing the productivity of an organization. A distinct characteristic of an effective performance assessment is the implementation of various methods that assess the conformity with multiple indicators and criteria. The present comprehensive review aimed to extract the factors affecting the performance assessment of the organization.
Methods: We conducted a comprehensive search in databases, including PubMed, Embase, SID, and Magiran, in January 2020. Inclusion criteria were articles with the English language and available full-text ones that were about influential factors on organization performance assessment. Two independent reviewers checked the research process and screening of the articles. Content analysis was used for data synthesis.
Results: A total of 18 articles were included in this study. Factors influencing organizational performance assessment were categorized into three themes and 22 sub-themes. The themes included performance assessment indicators, performance assessment criteria, and background factors in performance assessment.
Conclusions: Indicators, criteria, and background factors provide a framework for assessing the organization’s overall performance. An organization can manage its human resources effectively and efficiently by considering all effective factors. Identification and classification of influential factors can be of help for managers and decision-makers in creating a performance assessment system. Keywords:Organizational Performance Assessment; Measurement; Organizations; Occupational Groups
Identifying Emerging Trends in Scientific Texts Using TF-IDF Algorithm: A Case Study of Medical Librarianship and Information Articles
Authors: Dastani Meisam , Mousavi Chelak Afshin , Ziaei Soraya , Delghandi Faeze
Published: May 2021

Background: Nowadays, due to the increased publication of articles in various scientific fields, identifying the publishing trends and emerging keywords in the texts of these articles is essential.
Objectives: Thus, the present study identified and analyzed the keywords used in the published articles on medical librarianship and information.
Methods: In the present investigation, an exploratory and descriptive approach was used to analyze librarianship and information articles published in specialized journals in this field from 1964 to 2019 by applying text mining techniques. The TF-IDF weighting algorithm was applied to identify the most important keywords used in the articles. The Python programming language was used to implement text mining algorithms.
Results: The results obtained from the TF-IDF algorithm indicated that the words “Library”, “Patient”, and “Inform” with the weights of 95.087, 65.796, and 63.386, respectively, were the most important keywords in the published articles on medical librarianship and information. Also, the words “Catalog”, “Book”, and “Journal” were the most important keywords used in the articles published between the years 1960 and 1970, and the words “Patient”, “Bookstore”, and “Intervent” were the most important keywords used in articles on medical librarianship and information published from 2015 to 2020. The words “Blockchain”, “Telerehabilit”, “Instagram”, “WeChat”, and “Comic” were new keywords observed in articles on medical librarianship and information between 2015 and 2020.
Conclusions: The results of the present study revealed that the keywords used in articles on medical librarianship and information were not consistent over time and have undergone a change at different periods so that nowadays, this field of science has also changed following the needs of society with the advent and growth of information technologies.
Assessment of Computerized Medical Equipment Management and Maintenance System From Health Technology Assessment (HTA) Perspective: Need and Approach
Authors: Kumar Joshi Nitin , Pankaj Bhardwaj , Kuldeep Singh , Vibha Joshi , Praveen Suthar
Published: May 2021

Appropriate management of medical equipment is of crucial importance for providing quality healthcare. A computerized maintenance management system (CMMS) is a computerized program used by healthcare technology management (HTM) systems as an instrument for maintaining, organizing, storing, and reporting the data related to medical technologies in health facilities. Though CMMS is introduced as a beneficial and flexible tool for transforming the management of biomedical equipment, but no evidence of the same has been documented yet to highlight the efficacy of CMMS in the Indian context. CMMS, an e-Health system used by HTM programs, is a relatively new technology being adopted by various states of India. Such systems are vital to judging whether the system is operating and delivering the effects as desired. Assessment not only can inform policy-makers about what is known about the technology, but it also provides a better knowledge of the strengths and weaknesses of the intended technology. Health Technology assessment (HTA) is a systematic process designed to synthesize and evaluate the prevailing evidence for treatment or health delivery innovation. So considering the HTA perspective, an assessment approach to CMMS could be planned. Systematic reviews and empirical frameworks that have been used for understanding and assessing e-health programs can be used for evaluating technologies. Assessment of CMMS from a HTA perspective should be vital to the implementation of HTM systems by healthcare agencies.
Introduction
Authors: Gobbi Mary
Published: May 2021

When analysing the four papers that comprise this edition of the Journal, there were some quite similar themes, albeit with different perspectives. Essentially, the papers are considering different types of competences, their evolution over time, and the future needs of the work force in specific disciplines. What is fascinating is the emergence of a discourse of competences that is paradoxically extending and becoming more sophisticated on the one hand, yet on the other is confused, locally situated and difficult to define. We find competences being described as global, generic, scientific, technical, and associated with workplace learning. The geography of the papers provides a hierarchy of analysis from an international and global perspective to a sub-regional analysis of five countries (Europe), country based (Chile) and programme specific (The Netherlands).
A Comparative analysis of global competences within the framework of internationalized curricula
Authors: Beneitone Pablo , Yarosh Maria
Published: May 2021

An agreement seems to exist that graduates must be equipped with competences required to act successfully and appropriately in a global context. Many authors have proposed lists of competences that could form part of such a graduate profile which must be taken into account when designing internationalized curricula. However, merely listing of a competence does not guarantee that students develop it to the level expected by society. The present article reports on a meta-study based on eight Tuning studies. This meta-study compared the findings across the eight Tuning studies in terms of the different stakeholder groups’ ratings of importance and achievement of 11 global competences – generic competences valued by over 71,000 graduates, employers, students and academics in more than 100 countries and across four continents (Europe, Latin America, Africa and Asia). The contribution of the meta-study presented consists in offering a possibility to identify commonalities and differences among the perceptions of the four key stakeholder groups, not only across all the individual studies but also at the level of the four continents – something never accomplished until the present date. In addition, it will help identify the competences that might require particular attention of curriculum designers and teaching teams for students to develop these competences to the level perceived as optimal in different regions of the world. Future research questions are identified with the aim to enrich and validate or fine-tune these initial findings and compensate for the limitations related to the general timeline of the 8 individual Tuning studies that the meta-study built on.

Received: 31 March 2021Accepted: 06 May 2021
A poética do convite e as performatividades trans/formativas
Authors: Moraes Janaína
Published: May 2021

Nesse escrito compartilho reflexões sobre uma Poética do Convite enquanto agenciadora de campos de performatividade trans/formativa. Trans/formação enquanto as formações que se dão no trânsito. Lugar de passagem. Deslocamento. Ser artista, educador/a, pesquisador/a. Estudante, investigador/a. O ensino, a criação. A prática, a teoria. Transicionando por jornadas autônomas embora compartilhadas. Assim, aponto desafios de operar po/eticamente na perspectiva das querências compartilhadas.
Não atores e os sistemas
Authors: Gislon Giorgio Zimann
Published: May 2021

Nesta entrevista, realizada em fevereiro de 2019, nas proximidades dos Ufer Studios em Berlim, Stefan Kaegi afirma seu posicionamento crítico e teórico sobre teatro e comenta, especialmente, duas peças que estrearam recentemente: “Uncanny Valley” (2018) e “Granma. Trombones from Havana” (2019).
Inominável
Authors: Oliveira Jordana Mascarenhas de , Curi Alice  Stefania
Published: May 2021

O artigo se debruça sobre a dimensão ética mobilizada pelos modos de criação e compartilhamento da obra cênica “Inominável”. A proposta imersiva e singular dos processos de pesquisa e composição de persona~gens; o caráter íntimo de compartilhamento em cenas~encontro - nas quais uma única atriz/ator atua com um única espectadora/espectador; e a natureza aberta e performativa das dramaturgias - que abraçam devires a cada encontro, conferem ao trabalho um alto potencial de circulação de afetos.
Con-sentimento
Authors: Mendonça Gabriel Coelho , Lignelli César
Published: May 2021

A matriz popular da linguagem circense, herança dos artistas das feiras, tornou comum o número participativo, onde membros do público são convidados a contracenar com artistas. Faz-se necessário refletir sobre os limites éticos e o potencial transformador desta relação. Neste artigo reflito sobre minhas primeiras aventuras na realização de números de técnicas aéreas com participação de membros da audiência para propor uma relação de cumplicidade emocional como conduta ética na abordagem dos voluntários.
Para quem você dança?
Authors: Cálipo Nara , Rodrigues Graziela Estela Fonseca
Published: May 2021

O presente artigo tem como objetivo discutir a criação de uma obra de dança e a análise de sua recepção considerando o contexto e as espectadoras para as quais a mesma foi criada e apresentada: mulheres quebradeiras de coco babaçu e baiadoras de Terecô. O método de pesquisa e criação em dança, Bailarino-Pesquisador-Intérprete (BPI), foi utilizado na pesquisa e criação que deu origem aos dados em discussão. No percurso aqui descrito e discutido, procura-se evidenciar o aprofundamento propiciado pelo deslocamento de locais tidos como normativos para a criação e apresentação de obras coreográficas, para topologias tidas como outras, tais como comunidades e terreiros de Terecô ao norte do Estado do Tocantins.
Mother as curator
Authors: Black Sarah
Published: May 2021

This article and the research practice, ‘Mother as Curator’, speak directly to the mother developing art with her family, and addresses the ethical implications which arise this kind of performance making. The author discusses two pieces of work she has developed with her children, Oliver’s World (2014) and Isabel’s Shoes (2017). These performance works and encounters highlight and encourage performance making from different angles, acknowledging the ways in which art making as part of family life shifts perspectives on, and understandings of, what we mean be art practice and the ways it might be experienced.
VALIDAÇÃO DO ESCORE DE ALVARADO NO DIAGNÓSTICO DE APENDICITE AGUDA NOS PACIENTES DO HOSPITAL GERAL DE PALMAS: ANÁLISE RETROSPECTIVA DE 100 CASOS
Authors: Milhomem Luisa Coelho , Amorim Luiz Antônio Gomes , Cuellar Pedro Manuel González
Published: May 2021

RESUMO

Objetivos: determinar a sensibilidade e especificidade do escore de Alvarado para o diagnóstico de apendicite aguda nos pacientes admitidos na emergência do Hospital Geral de Palmas. Métodos: o estudo foi realizado com a validação de método diagnóstico através do escore clínico-laboratorial para diagnóstico de apendicite aguda. A amostra estudada consistiu de 100 pacientes admitidos na emergência do HGP com dor abdominal e suspeita de apendicite aguda, no período de março a outubro de 2017. Os pacientes foram atendidos na emergência e avaliados quanto ao escore de Alvarado pelo cirurgião responsável, o residente de cirurgia e os internos. Resultados: tomando como ponto de corte o valor >7 pontos, encontramos uma sensibilidade de 71,05 % e especificidade de 84,93 %. Conclusões: o escore de Alvarado é um método pouco invasivo para diagnóstico, simples, rápido, que utilizando o ponto de corte >7 pontos, apresentou-se como um instrumento de alto valor na triagem dos nossos pacientes com suspeita diagnóstica de apendicite aguda.

Palavras-chave: apendicite, diagnóstico, emergência.

ABSTRACT

Objectives: to determine the sensitivity and specificity of the Alvarado score for the diagnosis of acute appendicitis in patients admitted to the Emergency Hospital of Palmas. Methods: The study was performed with the validation of the diagnostic method through the clinical-laboratory score for the diagnosis of acute appendicitis. The sample consisted of 100 patients admitted to the emergency room of the HGP with abdominal pain and suspected of acute appendicitis, from March to October 2017. The patients were treated in the emergency room and evaluated for the Alvarado score by the surgeon in charge, the resident of surgery and the inmates. Results: taking as a cutoff value> 7 points, we found a sensitivity of 71.05% and specificity of 84.93%. Conclusions: The Alvarado score is a simple, fast, noninvasive method for diagnosis, which, using the cutoff point> 7 points was presented as a high-value instrument for the screening of our patients with suspected diagnosis of acute appendicitis.

Keywords: appendicitis, diagnosis, emergency.
FREQUENCY OF HEPATIC STEATOSIS IN A RADIOLOGY CLINIC IN PALMAS
Authors: Dias Filho David Ailton , Martins Reis Júnior Paulo , Andraus Wellington
Published: May 2021

ABSTRACT

Introduction: Recent studies suggest that hepatic steatosis is a worldwide distribution pathology that can progress to chronic liver disease with a highly unfavorable outcome resulting in the need for liver transplantation. That’s why early diagnosis is important. The liver biopsy’s considered a "gold standard" in its diagnosis, but the use of ultrasonography helps to detect steatosis in a non-invasive manner and is a very accessible method for the population. Objectives: To evaluate the frequency of steatosis in patients treated at a radiological clinic in Palmas using abdominal ultrasonography; observing its distribution in genders and age groups and its difference between 2010 and 2016. Methods: It was used ultrasound reports of abdomen of 3.222 patients made in 2010 and of 2.346 patients made in 2016. A longitudinal analysis was performed, between these two years, regarding the frequency of hepatic steatosis at the people and also between the genders and the age groups. Results: In 2010, 25,67% of people had hepatic steatosis in the ultrasound report, while in 2016 were 31,67%. In 2010, of the total number of people with steatosis, 52,48% were women and 47,52% were men; however in 2016, 51,94% were women and 48,06% were men. Regarding the age groups, in both periods, as in men and in women, steatosis was lower at the extremes of age and more frequent around the 5th to 7th decades of life. Discussion: The frequency of hepatic steatosis has increased in the period from 2010 to 2016. It was, as seen in the literature, quite high in the 5th and 6th decades of life, besides being more frequent in females. Unlike 2010, in 2016 begins to have children under 20 with signs of steatosis. Conclusion: In the year 2010 the frequency of hepatic steatosis was 25,67%, whereas in 2016 it was 31,84%.  

Keywords: Steatosis; ultrasonography; liver.
GRANULOMATOSE LINFOMATOIDE
Authors: Seraiedine Raissa Chagas , Mori Monise Marques , Guimarães Lucinda Calheiros
Published: May 2021

ABSTRACT

Lymphomatoid granulomatosis (LYG) is a rare extranodal Epstein-Barr virus (EBV) associated B-cell lymphoproliferative disorder. Most cases occur between the fourth and sixth decades of life and the male-to-female ratio is 2:1. The lung is the most frequently involved organ. Radiographically, pulmonary disease is characterized by multiple variable size nodules. Histologically, the lesions show angiocentricity, are rich in T cells, have large atypical B cells, lymphocytic infiltration of the vascular wall and a variable necrosis. LYG is a distinct entity that can usually be differentiated from other EBV-associated B-cell lymphoproliferative disorders on the basis of the combination of clinical presentation and histology. The authors described the case of a 53-year-old woman who was previously diagnosed with sarcoidosis, histoplasmosis, and later with non-Hodgikin B Lymphoma. The lungs presented diffuse alveolar damage, exsudative phase, and infiltration by lymphomatoid granulomatosis. The patient became unstable and died. Grading of these lesions is important because it dictates the treatment choice.

Keywords: Lymphomatoid granulomatosis, Epstein-Barr virus, pulmonary nodules.
MIOCARDIOPATIA NÃO COMPACTADA - UMA REVISÃO DA LITERATURA
Authors: Sousa Danilo Silva , I Eduardo Akio Pereira , Júnior Carlos Roberto de Oliveira , Paula Ricardo Mendonça de , Nunes Genildo Ferreira
Published: May 2021

RESUMO

Introdução - A miocardiopatia não compactada (MNC) é uma patologia de ocorrência familiar com histórico relevante de morte súbita e insuficiência cardíaca; é considerada como uma miocardiopatia não classificada pela Organização Mundial da Saúde (OMS). Segundo a Associação Americana de Cardiologia, é uma cardiomiopatia primária. Desenvolvimento - A MNC resulta de uma alteração genética que leva a uma parada do processo de compactação miocárdica, caracterizada pela persistência de trabeculações e recessos profundos que se comunicam com a cavidade ventricular. A apresentação clínica inicial varia de assintomático a apresentação de sintomas relacionados à dor torácica, insuficiência cardíaca e arritmias. Os principais métodos de diagnóstico para MNC são estudos ecocardiográficos e ressonância magnética cardíaca, tendo como principais diagnósticos diferenciais a forma apical de cardiomiopatia hipertrófica, a combinação de cardiomiopatia hipertrófica apical e MNC, cardiomiopatia hipertensiva, fibroelastose endocárdica, trombo apical ou tumores entre outros. Considerações finais - A terapêutica disponível inclui tratamento para insuficiência cardíaca, arritmias e eventos tromboembólicos, mas é necessário particularizar a terapêutica relacionada à anticoagulação e prevenção primária de morte súbita cardíaca.  

Palavras-chave: Cardiomiopatias; insuficiência cardíaca; arritmias cardíacas.

ABSTRACT

The left ventricular noncompaction (LVNC) is a patology with a familiar occurrence and relevant historic of sudden death and heart failure; it's considered an unclassified cardiomyopathy by World Health Organization (WHO). According to American Heart Association (AHA), it's a primary cardiomyopathy. Development - The LVNC results in a genetic alteration which leads to stop miocardial compaction process, characterized by persistence of trabeculation and deep intertrabecular recesses communicating with the ventricular cavity. The initial clinical findings may vary from asymptomatic to chest pain, heart failure and arrhythmias. The main diagnosis methods for LVNC are echocardiography and cardiac magnetic resonance imaging, having as main differential diagnosis the apical form of hypertrophic cardiomyopathy, a combination of both apical hypertrophic cardiomyopathy and LVNC, hypertensive cardiomyopathy, endocardial fibroelastosis, apical thrombus, or tumours among others. Final considerations - The menagement available includes the treatment for heart failure, arrhythmias and thromboembolic events, but it's neceassary particularize the therapeutics related to anticoagulation and primary prevention of sudden death.

Keywords: Cardiomyopathies; heart failure; cardiac arrhythmias.
TRABALHO DE PARTO PREMATURO
Authors: Soares Nayara Pettine Dias , Silveira Caroline Filardi
Published: May 2021

O trabalho de parto prematuro é a principal causa de morbi-mortalidade perinatal. O trabalho de parto pré-termo é aquele que ocorre em idades gestacionais abaixo de 37 semanas, desencadeado na maioria das vezes por múltiplos fatores evitáveis como processos infecciosos, baixo nível socioeconômico e educacional, assistência pré-natal deficiente e hábitos de vida. O diagnóstico clínico é dado por contrações uterinas regulares, associado a modificações do colo uterino e seus tratamento deve ser prontamente instituído, na ausência de contra indicações, utilizando-se de hidratação venosa, tocólise, corticóide e antibioticoprofilaxia. Entretanto, é primordial conhecer os principais fatores de risco para realizar o diagnóstico correto e precoce, a fim de se estabelecer medias terapêuticas efetivas, evitando um desfecho desfavorável.
INCIDÊNCIA DE ÓBITOS POR NEOPLASIAS, SEGUNDO LOCALIZAÇÃO PRIMÁRIA DO TUMOR NO ESTADO DO TOCANTINS DE 2006 A 2015.
Authors: Bitencourt Evandro Leite , Reis Júnior Paulo Martins , Rossato Renata , Araújo Sousa Bruno de Oliveira
Published: May 2021

Objetivo: Fazer um levantamento de óbitos ocorridos por neoplasias segundo a localização primária do tumor no Estado do Tocantins de 2006 a 2015. Métodos: Os dados foram obtidos através de acesso ao sítio do Instituto Nacional do Câncer (INCA). A seleção dos dados foi feita de acordo com a Classificação Estatística Internacional de Doenças e Problemas Relacionados com a Saúde (CID-10) 10ª edição. O grande grupo do CID-10 selecionado foi o de Neoplasias [tumores] malignas (os) que engloba os CID de C-00 a C97. Resultados: As neoplasias que causaram maior mortalidade no Estado do Tocantins foram a neoplasia maligna de brônquios e pulmões seguida pela localização primária desconhecida, neoplasias malignas da próstata, mama, esôfago, estômago, pâncreas, fígado, colo do útero e leucemia mieloide. Quanto à faixa etária, a idade que registrou o maior número de óbitos foi de 70 a 79 anos. Conclusões: Com essa pesquisa, observa-se semelhança entre o perfil da mortalidade por neoplasias no Estado do Tocantins e o Brasil. Deve ser incentivada a criação de políticas públicas voltadas a essa patologia e conscientização da população na tentativa de evitar essa alta mortalidade.  

Palavras-chave: Óbitos; Neoplasias; Sistemas de informação.

ABSTRACT

Objective: To make a survey of deaths due to neoplasms according to the primary location of the tumor in the state of Tocantins from 2006 to 2015. Methods: Data were obtained through access to the National Cancer Institute (INCA) website. Data were selected according to the International Statistical Classification of Diseases and Related Health Problems (ICD-10) 10th edition. The large group of ICD-10 selected was that of malignant neoplasms [tumors] that encompasses ICDs from C-00 to C97. Results: The neoplasms that caused the greatest mortality in the State of Tocantins were malignant neoplasms of the bronchi and lungs followed by the unknown primary site, malignant neoplasms of the prostate, breast, esophagus, stomach, pancreas, liver, cervix and myeloid leukemia. As for the age group, the age with the highest number of deaths was 70 to 79 years. Conclusions: With this research, there is a similarity between the profile of mortality due to neoplasms in the state of Tocantins and Brazil. It should be encouraged the creation of public policies aimed at this pathology and public awareness in an attempt to avoid such high mortality.

Keywords: Deaths; Neoplasms; Information systems.
SÍNDROME HELLP: A CONDUTA OBSTÉTRICA E SUAS CONTROVÉRSIAS
Authors: Oliveira Flávia da Silva , Moraes Fábio Roberto Ruiz de
Published: May 2021

RESUMO

A síndrome HELLP pode ocorrer na pré-eclâmpsia (PE) ou na eclampsia e se caracteriza pelo conjunto de sinais e sintomas associados à hemólise microangiopática, elevação de enzimas hepáticas e plaquetopenia, podendo afetar 0,6% das gestações e 4-12% das pacientes com PE grave. Responsável por elevados índices de mortalidade materna e perinatal, a paciente pode apresentar-se com mal estar geral, epigastralgia, dor em hipocôndrio direito, náuseas ou vômitos, cefaléia, escotomas, associados a quadro hipertensivo e proteinúria. A conduta obstétrica na Síndrome HELLP ainda apresenta controvérsias na literatura, principalmente quando estamos diante de gestações em estágio inicial. Existem condutas favoráveis ao tratamento conservador no intuito de estabilizar a progressão da doença e reduzir a morbidade e mortalidade da mãe e do feto. Outras que postergam a interrupção da gestação por período de 48 horas nos menores de 34 semanas. E ainda temos condutas obstétricas que adotam a interrupção de emergência, independente da idade gestacional.  

Palavras-chave: Síndrome HELLP, Pré-eclâmpsia grave, Eclâmpsia, gestação de alto risco.

ABSTRACT

HELLP syndrome is a clinical entity that can occur in pre-eclampsia or eclampsia and is characterized by presenting a set of signs and symptoms associated with mircroangiopathic hemolysis, raised elevated liver enzymes and thrombocytopenia, which may affect 0.6% of pregnancies and 4-12% of patients with severe PE. Responsible for high rates of maternal and perinatal mortality, the patient may present with general malaise, epigastralgia, right hypochondrium pain, nausea or vomiting, headache, scotomas, associated with hypertension and proteinuria. The obstetric behavior in HELLP syndrome is still controversial in the literature, especially when we are in the early stages of pregnancy. It was observed that some authors favor conservative treatment in order to stabilize the progression of the disease and reduce morbidity and mortality of the mother and the fetus. However, other authors take the course of postponing gestation of less than 34 weeks per 48-hour period. And we still have obstetric behaviors that adopt the emergency interruption, regardless of gestational.
Meta-Analysis of Smooth Muscle Lineage Transcriptomes in Atherosclerosis and Their Relationships to In Vitro Models
Authors: Conklin Austin C. , Nishi Hitoo , Schlamp Florencia , Ord Tiit , Ounap Kadri , Kaikkonen Minna U. , Fisher Edward A. , Romanoski Casey E.
Published: May 2021

Background:

Vascular smooth muscle cells (VSMC) exhibit phenotypic plasticity in atherosclerotic plaques, and among other approaches, has been modeled in vitro by cholesterol loading.

Methods:

Meta-analysis of scRNA-seq data from VSMC lineage traced cells across five experiments of murine atherosclerosis was performed. In vivo expression profiles were compared to three in vitro datasets of VSMCs loaded with cholesterol and three datasets of polarized macrophages.

Results:

We identified 24 cell clusters in the meta-analysis of single cells from mouse atherosclerotic lesions with notable heterogeneity across studies, especially for macrophage populations. Trajectory analysis of VSMC lineage positive cells revealed several possible paths of state transitions with one traversing from contractile VSMC to macrophages by way of a proliferative cell cluster. Transcriptome comparisons between in vivo and in vitro states underscored that data from three in vitro cholesterol-treated VSMC experiments did not mirror cell state transitions observed in vivo. However, all in vitro macrophage profiles analyzed (M1, M2, and oxLDL) were more similar to in vivo profiles of macrophages than in vitro VSMCs were to in vivo profiles of VSMCs. oxLDL loaded macrophages showed the most similarity to in vivo states. In contrast to the in vitro data, comparison between mouse and human in vivo data showed many similarities.

Conclusions:

Identification of the sources of variation across single cell datasets in atherosclerosis will be an important step towards understanding VSMC fate transitions in vivo. Also, we conclude that cholesterol-loading in vitro is insufficient to model the VSMC cell state transitions observed in vivo, which underscores the need to develop better cell models. Mouse models, however, appear to reproduce a number of the features of VSMCs in human plaques.
Talk between Dussel and Forner-Betancourt: dialogue between philosophical knowledge, interculturality and indigenous school education
Authors: Moraes Júnior Henrique , Oliveira Ivanilde Apoluceno de
Published: May 2021

Summary The article focuses on Enrique Dussel's Philosophy of Liberation, with the aim of reflecting on the articulation between modernity, the Eurocentric paradigm and the world paradigm. In this sense, the article develops the discussion on rationality and irrationality of modernity (myth of modernity) and its transmodernity (overcoming), as it is directly related to the question of the negative dialectical method with the negation of otherness - of indigenous populations - in philosophical systems. Eurocentric totality and points out the analytical movement as overcoming, expanding and liberating the negative dialectical method. It also outlines the intercultural philosophy of Rául Fornet-Betancourt, which aims at a symmetrical dialogue between philosophical knowledge. It is inferred, from the Liberation of the Other as Alterity and Interculturality, the concrete existence of a dialogical relationship between philosophical knowledge, enabling greater cosmological, philosophical and educational enrichment, as well as the teaching of intercultural philosophy in indigenous schools. In this study, the bibliographic review is the methodological strategy used.
Energy Efficiency as a tool to improve buildings behavoir In Egypt. A frame work to achive low energy buildings locally.
Authors: Abd El Aal Heba Mahrous Ali
Published: May 2021

Sustainable development goals for 2030 depending on how to create abetter life for pepole  including all parameters which affect human  to avoid the negative impacts  of climate change  which can destroy life on our plante.Saving energy is one of the main global problems, and buidings are one of the influences on energy consumption. It is a must to solve this problem by identifiy the causes which  includinng the building features, operation process  and the impact of its occupants . On the other hand, clarify permanent solutions according to modern concepts and techniques which can help to solve it locally.The study attempts to clarify human, nature environment and built environment impacts , in indicating how  building Play an active role in achieving virous stages of energy consumption or production  to adress the enegy effeciency importance.This paper discusses this issues and gives recommendations and proposals on how to solve problemsensure the achievement of low energy buildings in Egypt depending on the parameters which respect and  depend on our local environment in Egypt.
The Association Between Using a Mobile Version of an Electronic Health Record and the Well-Being of Nurses: Cross-sectional Survey Study
Authors: Heponiemi Tarja , Kaihlanen Anu-Marja , Gluschkoff Kia , Saranto Kaija , Nissinen Sari , Laukka Elina , Vehko Tuulikki
Published: May 2021

Background

Mobile devices such as tablets and smartphones are increasingly being used in health care in many developed countries. Nurses form the largest group in health care that uses electronic health records (EHRs) and their mobile versions. Mobile devices are suggested to promote nurses’ workflow, constant updating of patient information, and improve the communication within the health care team. However, little is known about their effect on nurses’ well-being.

Objective

This study aimed to examine the association between using a mobile version of the EHR and nurses’ perceived time pressure, stress related to information systems, and self-rated stress. Moreover, we examined whether mobile device use modifies the associations of EHR usability (ease of use and technical quality), experience in using EHRs, and number of systems in daily use with these well-being indicators.

Methods

This was a cross-sectional population-based survey study among 3610 Finnish registered nurses gathered in 2020. The aforesaid associations were examined using analyses of covariance and logistic regression adjusted for age, gender, and employment sector (hospital, primary care, social service, and other).

Results

Nurses who used the mobile version of their EHR had higher levels of time pressure (F1,3537=14.96, P<.001) and stress related to information systems (F1,3537=6.11, P=.01), compared with those who did not use mobile versions. Moreover, the interactions of mobile device use with experience in using EHRs (F1,3581=14.93, P<.001), ease of use (F1,3577=10.16, P=.001), and technical quality (F1,3577=6.45, P=.01) were significant for stress related to information systems. Inexperience in using EHRs, low levels of ease of use, and technical quality were associated with higher stress related to information systems and this association was more pronounced among those who used mobile devices. That is, the highest levels of stress related to information systems were perceived among those who used mobile devices as well as among inexperienced EHR users or those who perceived usability problems in their EHRs.

Conclusions

According to our results, it seems that at present mobile device use is not beneficial for the nurses’ well-being. In addition, mobile device use seems to intensify the negative effects of usability issues related to EHRs. In particular, inexperienced users of EHRs seem to be at a disadvantage when using mobile devices. Thus, we suggest that EHRs and their mobile versions should be improved such that they would be easier to use and would better support the nurses’ workflow (eg, improvements to problems related to small display, user interface, and data entry). Moreover, additional training on EHRs, their mobile versions, and workflow related to these should be provided to nurses.
Design of a Virtual Reality Interactive Training System for Public Health Emergency Preparedness for Major Emerging Infectious Diseases: Theory and Framework (Preprint)
Authors: Luo Yue , Li Mei , Tang Jian , Ren JianLan , Zheng Yu , Yu XingLi , Jiang LinRui , Fan DingLin , Chen YanHua
Published: May 2021

BACKGROUND

Sufficient public health emergency preparedness (PHEP) is the key factor in effectively responding to and recovering from major emerging infectious diseases (MEIDs). However, in the face of MEIDs, PHEP is insufficient, so it is necessary to improve PHEP. The rapid development of virtual reality and human-computer interaction provides unprecedented opportunities for innovative educational methods.

OBJECTIVE

This study designed a virtual reality interactive training system (VRITS) to provide an effective path for improving PHEP in the context of MEIDs so that the public can effectively respond to and recover from MEIDs.

METHODS

This study used interactive narrative, situated learning and human-computer interaction theories as a theoretical framework to guide the design of the system. We used the literature research method and the Delphi method; consulted multidisciplinary experts, such as infectious diseases, disease control, psychology, and public health personnel, to determine the educational content framework; and set up an interdisciplinary team to construct an operating system framework for the VRITS.

RESULTS

We named the VRITS “People’s War Against Pandemic.” The educational content framework includes 20 knowledge, emotion, and behavior skills in 5 aspects (cooperating with prevention and control work, improving emergency response ability, guaranteeing supplies and equipment, preparing economic resources, and maintaining physical and mental health). The operating system framework includes virtual interactive training, knowledge corner, intelligent evaluation, and community forum modules, and the core module is the virtual interactive training module. In this module, users control virtual characters to move in various scenes, and then identify and analyze the controllability and harmfulness of the evolving pandemic and select the correct prevention and control strategy to avoid infecting themselves and others.

CONCLUSIONS

The development and sharing of the multidisciplinary theoretical framework adopted by People’s War Against Pandemic can help us clarify the design ideas and assumptions of the VRITS; predict training results; understand the ability of training to change emergency knowledge, emergency emotion, and behavioral responses to MEIDs; and promote the development of more effective training systems based on virtual reality.
The factors of eHealth literacy and the association between intrinsic capacity and eHealth literacy among hospitalized older adults: a cross-sectional study (Preprint)
Authors: Shao Zhanfang , Hu Mingyue , Zhang Dou , Li Xiao Yang , Zeng Xianmei , Liu Qingcai , Feng Hui
Published: May 2021

BACKGROUND

The factors of eHealth literacy are unclear. The relationship between intrinsic capacity and eHealth literacy needs to evaluate.

OBJECTIVE

The study aims to evaluate the level and factors of eHealth literacy, and investigate the association between intrinsic capacity and eHealth literacy among hospitalized older people.

METHODS

Data was collected from January to February 2021 in two hospitals, Hunan, China. Intrinsic capacity and eHealth literacy were assessed using validated questionnaire recommended by WHO and eHEALS scale. One-way analysis of variance was used to identify the factors of eHealth literacy. Multiple linear regression was used to examine the association between intrinsic capacity and eHealth literacy.

RESULTS

The mean score of eHealth literacy and IC were 6.56±1.59, 19.10±10.65 respectively. The eHEALS score differed significantly (P<0.05) with respect to age, residence, education, retirement, individual income level, medical insurance, taking medication, pension insurance, self-reported health, grandchild caregiver. Multiple linear regression analysis showed that higher level of intrinsic capacity, locomotion, cognition, vitality and psychology were significantly related to higher eHealth literacy. Cognition was most associated with eHealth literacy

CONCLUSIONS

Intrinsic capacity was related to eHealth literacy. Improving intrinsic capacity could be an effective way to boost eHealth literacy among hospitalized older adults.