bluuebunny/crossref_metadata_2025 huggingface dataset:
Influence of Socio-economic and Demographics factors on Households’ Savings in Sri Lanka
Authors: Ruwan Jayathilaka  , Thisum Palihawadana  , Inuri Amalka  , Sandupama Jayasinghe  , Pulith Jayarathne
Published: December 2022

The purpose of this paper is to examine the factors influencing saving behavior among households in a developing country. Sri Lanka being a developing country, has recorded a relatively lower households’  saving rate when compared with its peer regional counterparts. The study approximates the socio-economic and demographic factors towards the level of saving of households in Sri Lanka using a quantile regression approach based on the Household Income and Expenditure Survey, conducted by the Department of Census and Statistics of Sri Lanka. Results were obtained by using the stepwise quantile regression technique. The findings of this study conclude that when Sri Lankan households have a higher per-capita income, they tend to have a higher saving level. Moreover, age and marital status have a significant impact on the level of saving in Sri Lankan households. Additionally, poverty and employment status have a significant impact to the level of saving on Sri Lankan households. This research paper bridges empirical gaps in this area of study. Furthermore, this study has been conducted encompassing the entire country rather than limiting it to a district or segment, hence, is comprehensive. As per the generated results gender, income and education levels have shown a significant positive impact towards the level of saving, whilst marital status and poverty have shown a significant negative impact towards the level of saving. It is considered that when the demographic and socio-economic factors are affecting favorably, the level of saving tends to increase and vice versa. Accordingly, findings of the study can provide insights to policymakers to devise policies and incentives to encourage savings behaviour and level of savings among households in Sri Lanka. This is beneficial as coping strategies specially during crises, where dependency of households on government assisted welfare schemes is likely to be less.

Keywords: Household Saving Behaviour, Motives of Savings, Barriers to Saving, Quantile Regression
Customers' Technology Know-How and Error-Correction Capability in using Self-Service Technologies
Authors: B.S. Galdolage
Published: December 2022

Customers' levels of technology knowledge vary significantly, affecting their performance in Self-Service Technologies (SSTs) and their ability to respond to errors in SSTs caused by service or process failures. Despite the fact that this is a highly practical scenario, scholarly research on the subject is rare. Thus, the purpose of this research is to look into customer technology know-how in SSTs, their corrective actions in the event of SST service/process failures, and differences among customers in terms of service performance, technology know-how, and error corrective capabilities in SSTs. A qualitative approach was used to achieve the research objectives, with semi-structured interviews conducted with 25 SST users from various demographic backgrounds. A non-probabilistic purposeful sampling strategy was used to recruit individuals for the study, with the goal of hiring information-rich cases. Thematic analysis was used to analyze the data. The study identified four types of knowledge that SST users need to effectively complete service transactions: computer knowledge, SST device knowledge, Internet knowledge, and language ability. Furthermore, the study identified numerous mechanisms used by customers to correct errors in SSTs and classified them as 'error preventing' or 'error recovering' mechanisms. Additionally, the study discovered customer performance disparities among SSTs based on their level of technological expertise and error-correcting capabilities. The study divided SST users into three performance categories: 'Full performer,' 'Fair performer,' and 'Poor performer.' The study contributes new knowledge by elucidating the interaction between SST users' technological expertise and error correction capabilities, a phenomenon that is rare in the previous literature, and contributing to the marketing theory by developing a typology to group customers based on customers’ level of technological expertise and error-correcting capabilities. In the practical ground, it informs SST service providers on how to maximize users' level of expertise while improving the service quality.

Keywords: Self-service technologies, Technology know-how, Errors in SSTs, SST acceptance
Efficacy and Concerns of Technical Project in Bangladesh: An Assessment of the Managing at the Top 2 (MATT2) Project
Authors: Mohammad Rezaul Karim  , Byomkesh Talukder  , Afia Rahman
Published: December 2022

Least-Developed Countries (LDCs) and developing countries receive various supports for their development and technical projects from developed nations and development partners. Bangladesh is no exception. Managing at the Top 2 (MATT2) is a technical development project that was designed in collaboration with the governments of the UK and Bangladesh and carried out in Bangladesh with funding of the UK. The primary aim of the project was to provide practical training for approximately 2000 top-level officials of the Bangladesh Civil Service to enhance their efficiency in developing and implementing innovative projects to deliver public services. In this paper, the purpose, process and results of the project are analyzed using a qualitative approach to understand the benefits and barriers of the project. It was found that MATT2 produced remarkable success, with 305 performance improvement projects (PIPs) were developed and implemented by the participating bureaucrats. Government employees were benefitted from practical knowledge on project preparation, skill development and the citizens were benefited from the outputs. Although the project claims 100% success in terms of implementation, projects were influenced by some bottlenecks that include unsuitability of PIPs, lower reform value, monetary motivation and selection of project area out of the participants’ jurisdiction.  The authors suggest considering the intended and unintended consequences of the MATT2 to undertaking similar projects in the future.

Keywords: Bangladesh; Civil servants; Development; Experiential learning; PIPs; Skill development
Online forum use in child attracted persons
Authors: Roche Kailey , Stephens Skye , Moss Sarah , Seto Michael C.
Published: December 2022

Social support for child-attracted persons (CAPs) may be important for increasing well-being, thereby reducing the risk of committing child sexual abuse. Unfortunately, in-person social support may be difficult to obtain because of stigma. CAPs may instead turn to online forums for people who are sexually attracted to children. The present study looks at the emotional, informational, and tangible support CAPs offered and received through online forums. We recruited 353 CAPs from Twitter and multiple online forums. The survey covered basic demographics, frequency of forum use, reasons for forum use, social support received or offered, helpfulness of forums, and their quality of offline support. Most CAPs said that they initially sought out forums to avoid feeling alone in their attraction; the quality of offline support was rated as moderate. Emotional support and informational support were the most frequently endorsed forms of social support. CAPs who visited more forums reported forums to be less helpful, which could reflect “forum shopping.” A Poisson regression predicting online support from quality of offline support and various demographic and forum use variables did not reveal any significant results. This is the first quantitative study to look at the benefits of forums for CAPs regarding specific types of social support. The authors consider if certain forums, in addition to professional help, could be part of a repertoire of resources for CAPs who may be struggling.
Еducation of patriotism in the children of preschool age in ukraine (1930-1941)
Authors: Lushpay T.
Published: December 2022

the article considers the problem of patriotic upbringing of preschool children in the period 1930-1941 against the background of political changes in the country. Their focus on solving the problem of patriotic revival of the Ukrainian people, on the creation of a national preschool educational system on the basis of nationality, the education of the younger generation on the traditions and achievements of folk pedagogical thought. The content of the source base of the 30s-40s of the XX century is analyzed. The essence of the concept of "sense of patriotism" is defined. It is determined that in 1930-1941 there was a rise in the development of preschool education and education of patriotism in preschool children, a period of decline of the preschool education system was the beginning of World War II.
Civil value of modern students
Authors: Khrystenko О.
Published: December 2022

Ukrainian youth face the task of developing their civic values system according to the modern socio-political military challenges and the peculiarities of their professional vocation. Therefore, the aim of our research was to investigate students' views on the ideal society and the main values of Ukrainian society in the wartime. We used the method of content analysis of written creative works (essays) of second-year students of Ternopil National Medical University, inductive method for processing research results, methods of theoretical, historical and pedagogical analysis. According to the results of the study, key concepts that reflect the civic values and expectations of modern youth have been defaned: freedom, independence, responsibility, individualism, morality, dignity, happiness, equality, justice, honesty, courage, wisdom, openness, sensitivity, kindness, love, family. Future doctors named moral responsibility as a necessary condition for an ideal society. They stated about transformation of values in wartime – from the priority of material values to fundamental existential ones as well. It is concluded that the professional training of medical university students concerning the development of skills of enlightenment work among the population should be strengthened so that young persons contribute to the promotion of constructive civic values in the university environment today and in future professional activities.
Provision of psychosocial assistance to children under the conditions of marital state
Authors: Vlasenko К.
Published: December 2022

The article is devoted to the problem of effective provision of professional psychosocial assistance to children under martial law. It is noted that psychosocial assistance to children and adolescents who have undergone a traumatic experience will largely depend on their individual psychological characteristics. For many children, traumatic experiences have effects that last much longer and can develop into post-traumatic stress disorder. The main stages of providing psychosocial assistance to children during martial law are highlighted. It is suggested to establish primary emotional and positive psychological contact with the child. The main goal of providing psychosocial assistance to children under martial law conditions is clarified: reducing emotional stress in a child or teenager; formation of emotional and trusting contact of the specialist with the child. When providing psychological and social assistance to children affected by martial law, it is recommended to pay attention to the following actions: give children the opportunity to talk with loved ones as much as they need; check your feelings (repeat the words they use and thus show that you understand them); provide a sense of security; calm the child; find something that helps you cope with difficult feelings; to spend time with benefit, doing what the child likes; seek help from specialists. When establishing psychological contact with the child, it is necessary to take into account its age characteristics, and the main form of work with the child should be individual. At the final stages, it is suggested to use group forms of work. According to practical experience, the most effective methods and techniques are: fairy-tale therapy, art therapy, play therapy, hippotherapy, etc. The choice of method or technique will depend on how strong the traumatic event was, the age and individual characteristics of the child. Assessment of the child's psycho-emotional state can be carried out using the same methods and techniques that were used in the framework of diagnosis and individual work with the child.
The Issue of Key Terms of Lingvopragmatics
Authors: Pasternak T. , Teteruk S.
Published: December 2022

The article has determined the term “pragmatics” as a subfield of linguistics, which investigates: linguistic forms and ways via which speakers realize their goals and tasks; communicative actions carried out while speaking; as well as the conditions under which communication takes place.The purpose of the research is to present the existing views on the problem of pragmatics in modern linguistic science, and analyse the main categories of linguistics for the study of communicative behavior of the speakers. The current interest of this issue arises from the lack of comprehensive coverage and generalization of key categories of pragmalinguistics.We have analysed the main categories of linguopragmatics such as pragmatic context, deixis, reference, inference, implicature, presupposition as well as the types of speech acts in the context of pragmalinguistic analysis.The key conclusion of the research is that the linguistic pragmatics contributes to the interpretation processes not only of what the speakers speak directly, but also of what they “mean” and how successful the communication is. Lingvopragmatics considers all types of contextual meaning of words, takes into account the context of communication, reference identifiers, inferred meanings based on hints, background knowledge, deictic expressions, implicatures and presuppositions of speakers and hearers. The analysis of speech acts by the type of illocution and perlocution helps to interpret communicative goals and intentions of the speaker, as well as to predict the impact of utterances on the listener.
Explication of the Motif of Alienation and the Forms of Its Overthrow in I. Mcewan’s Novel «Solar»
Authors: Drozdovskyi D.
Published: December 2022

The research of Ian McEwan’s novel “Solar” (2010) will help to delineate the transformational dynamics of the postmodern to post-postmodern novel and to characterize the configurations of such changes in the contemporary British novel.The purpose of the study is to outline the thematic units and problem areas that reveal the genre specifics of the contemporary British novel, determining the narrative feature of the novel “Solar” by I. McEwan.Results of research. It has been determined in what way the ironic mode is represented in the novel “Solar”. The philosophical parameters of the narrator, the worldview characteristics of the protagonist, the way of interaction of irony and seriousness (philosophical, confessional) in the novel, which British literary critics describe as an example of a comic work, have been discussed. At the same time, the spectrum of socio-psychological problems that reveal the critical attitude of the narrator to a number of problems of the contemporary academic science has been analyzed. The innovative aspects explained in the novel, in particular at the thematic level (new complexes of existential problems related to the devastation of the protagonist, his alienation and loss of values in life), as well as the general guidelines of the narrator (author) on innovation, which is realized even in the linguistic aspect due to the excess of occasionalisms (author's neologisms) have been outlined. The way in which external conditions determine Michael’s alienation is studied, and it has been determined how the motif of the path (way) explicated in the novel helps the character to be “born again” in the “new life”. It is analyzed what internal transformations take place inside the character in order to break the vicious circle of academic and existential problems and reach the level of perception of life in the categories of purpose and happiness. The scope of problems related to the critique of the contemporary science (imitation, plagiarism, bureaucracy, routine and numerous bureaucratic obstacles to innovative researches, lack of interest, banal fatigue experienced by the protagonist, and unwillingness to help younger colleagues in the implementation of their heuristic projects, etc.) have been spotlighted in the research .
Creative Heritage of Borys Oliinyk in the National Dimension
Authors: Chumak T.
Published: December 2022

Abstract. The article deals with the creativity of Borys Oliinyk as a representative of Ukrainian culture of the 20th century in terms of national spiritual values. It is proved that Oliinyk’s worldview beliefs are a reflection of the history of the Ukrainian people, its morals, national traditions. It was proved that the main problems in the works of the artist are the problems of life and death, human values and human empathy, happiness and freedom, the artist’s duty before the nation. The poet urged in his works to be responsible for everything in the life of his native people. The poet imprinted his artistic credo in many verses and poems, the main idea of which is sincerity and honesty, the praise of the image of the mother, purity and incorruptibility of the poetic word, deep respect for the elderly and older people, mercy, humanity, hard work, sacrifice for the victory over evil.The works of Borys Oliinyk constitute a significant page in the history of Ukrainian literature. His name is included in all anthologies of world art, electronic resources and encyclopedias. Comprehension of Oliinyk’s creative heritage. Oliinyk as a poet, tribune, statesman has found a wide echo in the studies of philologists, writers, literary critics, critics, etc.It is obvious that the leading motifs of Borys Oliinyk’s works are unity of generations, the statement of universal and national moral values, which spiritually grow a person, as well as philosophical reflections on contemporary problems in the context of the historical experience of our people, and all of humanity. Appeal to the tragic page of the Ukrainian nation during the Second World War makes poems by Boris Oliynyk urgent in the light of current events, in times of invasion of the newest putin’s fascism on our land.
Latin for Bachelors in Water Bioresources and Aquaculture: a Linguodidactic Aspect
Authors: Balalaieva O.
Published: December 2022

Today’s society needs qualified specialists in aquaculture who are proficient not only in the native language but also in international professional one, are familiar with the scientific conceptual terminology apparatus of modern European languages. The purpose of the article is to study ways to implement professional linguodidactic key concepts and principles in teaching and learning Latin on the example of the educational program “Water bioresources and aquaculture” which led to the choice of such research methods: analysis of scientific literature to study state of the problem, synthesis and generalization. The study found that, Latin is the integral component of bachelors training, but can hardly be considered on an equal basis with any other LSP: teaching and learning living languages are aimed at forming students’ foreign language professional communicative competence, but in case of Latin focus on the formation of professional terminological competence. Therefore, it can be considered in the context of professional linguodidactics, key concepts and principles of which (interdisciplinary integration, internationalization, selectivity) can be implemented in the educational process. In the reviewed program, the component “Latin” reveals intersubject connections with most disciplines both general and special training cycles, that as a whole assumes interconnection, interdependence and complementarity of intersubject information and ways of learning. So learning professionally oriented Latin is a holistic, complex and integrative process of development specialist’s linguistic personality. That is why it can be of scientific interest not only in the framework of methodology, but also very promising in linguodidactic, terminological, cognitive and other aspects for further research.
Some Desiderata in Teaching Scientific And Legal LSP in Modern Greek: The Case of Loanwords
Authors: Krimpas P. , Chaika O.
Published: December 2022

Classical Greek has traditionally been a language used as a source of LSP for other European languages in various thematic areas. Standard Modern Greek, however, borrows rather than lends LSP, which mostly involves re-borrowing of terminology coined on the basis of (originally) Greek roots, stems, affixes and combining forms. This poses the problem of adaptation to the phonological (especially phonotactic) and morphological system of Standard Modern Greek. A closer study of selected cases shows that the ISO term formation principles of linguistic correctness and consistency are not always observed. Occasionally, terminological choice is possible, with one form that observes the above-mentioned principles and another that does not observe them being available. Therefore, with this empirical research the methodology rests on Google Search method for identifying so called terminological doublets, in the end focusing on the case study and description of the four Greek terms – ψυχεδέλεια psychedelia’, κοσμετολογία cosmetology’, πλαγκτόν plankton’, and ιονισμός ionisation’; the terms have undergone the terminological check-up’ as to alignment with the set requirements against the term formation principles, and bring into focus the didactic facet of teaching LSP in general. Next, striving for adoption of the unified approach in teaching special terminologies may be considered leading under the discussed framework. Given that both multi-cultural and poly-cultural communicative settings such as language teaching and/or translation require an awareness about linguistic perceptions of the Other’ in order to have mutually beneficial results, the recommended terminological choices of the language teacher and/or the translator are discussed, starting from examples of problematic borrowed terms currently used in scientific and legal contexts. The conclusion is that, although descriptive approaches are mainstream in linguistics, in the case of terminology borrowing into once influential languages that claim an uninterrupted history such as Greek a prescriptive approach is sometimes preferable.
The Formation of Foreign Language Communicative Competence in the Context of the English Perception as a Global Lingua Franca
Authors: Khrystiuk S.
Published: December 2022

The current research is aimed at analyzing modern problematicity of forming foreign language communicative competence in the context of the English perception as a global lingua franca. It considers foreign language communicative competence of university students as an ability to communicate and exchange views in various situations while interacting with other communicators, properly using the system of linguistic and speech norms, choosing communicative behavior adequate to the authentic communication situation. English as a Lingua Franca is perceived as the most common contact language for interethnic communication, which implies a global use of English linguistic data by speakers with different linguistic and cultural characteristics; it can be defined as a dynamic resource experiencing constant change, a modifiable means of communication rather than an established model; it is widely described as an adaptive, contingent, creative, changing, dynamic, flexible, fluid, fragmented, fuzzy, heterogeneous, hybrid, unpredictable, but self-regulating system, and a particularly ad hoc and emergent form of everyday communication involving a virtual speech community, or different constellations of speakers of diverse individual Englishes in every single interaction. The study highlights that ELF is monolithic and monocentric, a monomodel’ in which intercultural communication and cultural identity are to be made a necessary casualty; it operates at local, national, regional and international levels. The spread of English is viewed in terms of three concentric circles (inner, outer, expanding), representing the spread types, the acquisition patterns and functional domains.
O FEMINISMO NO BRASIL
Authors: Mendes Mariana Lucas , Ribeiro Cristiane Maria
Published: December 2022

Este trabalho é um recorte da pesquisa de mestrado intitulada A Participação das Mulheres na Gestão do Instituto Federal Goiano - Campus Urutaí: uma perspectiva histórica (1953-2019), que teve como objetivo investigar a participação da mulher na gestão do Instituto Federal Goiano - Campus Urutaí. Trata-se de uma pesquisa documental e bibliográfica, na qual foi desenvolvida uma revisão de literatura buscando traçar o histórico dos movimentos feministas no Brasil e as vertentes mais atuantes. Ao final da pesquisa, percebe-se que, antes dos movimentos feministas, já haviam movimentos de mulheres organizados em prol de diversas pautas. Entendemos também que o Feminismo é um movimento plural, isto significa que movimentos feministas possuem diversas vertentes, incluindo diferentes aportes teóricos, ideológicos e políticos.
“AMANTE NÃO TEM LAR”: RUPTURA E PERMANÊNCIA NA CANÇÃO DE MARÍLIA MENDONÇA
Authors: Lourenço Elaíny Martins , Melo Samuel Carlos , Fernandes Fernanda Surubi
Published: December 2022

Esse trabalho tem como objetivo compreender como a condição da mulher na sociedade contemporânea é materializada na letra da canção “Amante não tem lar” (2017), de Marília Mendonça, a partir das relações de ruptura e permanência que ela estabelece com a tradição da música sertaneja produzida por mulheres. Nesse sentido, partimos da problematização sobre o feminismo e a sexualidade marcadas nos processos históricos e sociais. Em seguida, buscamos localizar o espaço da mulher na música sertaneja, por meio de uma breve historicização do gênero. Por fim, analisamos as rupturas e permanências de elementos da tradição da música sertaneja na letra de “Amante não tem lar”. Para isso, baseamos em Orlandi (2007), Pêcheux (1990), Hooks (2018), Alves e Pitanguy (1985), dentre outros.
UM ESTUDO DA OBRA DE CAROLINA MARIA DE JESUS E OS DIREITOS FUNDAMENTAIS
Authors: Muniz Aline De Assis Rodrigues Amaral , Melo Nabya Carollynne Rodrigues de , Santana Isabella Borges
Published: December 2022

O presente trabalho tem por objetivo desenvolver uma abordagem sobre as obras de Carolina Maria de Jesus e os artigos de reflexões, análises e direitos sociais, do ponto de vista jurídico social, devendo também responder a seguinte questão: “Os direitos sociais de Carolina Maria de Jesus foram violados?”. Além disso, refletir sobre as bases teóricas dos direitos sociais, bem como perceber como são estruturados os direitos sociais na Constituição Federal e entender como funciona a questão dos direitos sociais como direitos fundamentais na obra de Carolina Maria de Jesus. A metodologia utilizada foi de pesquisas bibliográficas, com a devida revisão de literatura relacionada à temática, sendo utilizados livros, artigos, sites e outras fontes.
“A CONVERSÃO DE SÃO PAULO”: O INTERDISCURSO NA PREGAÇÃO DE JOSÉ DE ANCHIETA
Authors: De Souza Bruno Felipe
Published: December 2022

Com base no conceito de interdiscurso postulado no quadro teórico da Análise do Discurso francesa, analisamos o sermão histórico “A Conversão de São Paulo”, de autoria do Padre José de Anchieta. O trabalho teve como objetivo investigar o interdiscurso revelado na pregação religiosa. Para a realização da pesquisa baseamo-nos em pressupostos desenvolvidos pelo teórico francês Dominique Maingueneau. Os resultados indicaram que o sermão surge como espaço discursivo em que há abundante incidência de interdiscursos. Quanto às relações interdiscursivas presentes na pregação, evidencia-se a menção ao discurso das escrituras bíblicas e aos formados pela tradição católica.
SALA DE AULA INVERTIDA E APRENDIZAGEM COMPORTAMENTAL APLICADA AO ENSINO DE PROGRAMAÇÃO
Authors: Gonçalves Anderson Cavalcante , Ferreira Deller James
Published: December 2022

A sala de aula invertida muda a forma pela qual a aprendizagem ocorre, transformando o aluno em um agente ativo da aprendizagem. Para que o potencial da sala de aula invertida possa ser aproveitado adequadamente é importante que o aluno autorregule suas atividades individuais e em grupo. A aprendizagem comportamental possui perspectivas que podem contribuir para a estruturação do comportamento e melhorar a aprendizagem. Neste artigo é implementado o comportamento operante de Skinner para apoiar a aprendizagem. Foi realizado um estudo qualitativo que indicou sucesso no potencial do uso da sala de aula invertida aliada a aprendizagem comportamental com foco no ensino de programação.
Impacts of Climate Change on Household Income Level of the Farmers: The Case of Sarayonu District of Konya Province in Turkey
Authors: ISLAM Mozharul
Published: December 2022

Climate change is already a common phenomenon to people from all walks of life worldwide. Climate characteristics are essential for sufficient agricultural production to keep the income balance of the households of the producers. However, changes in climate characteristics bring changes in agricultural output which consequently affects the income levels of the producers. This study aims to explore how changes in global climate bring changes in water levels, consequently affecting the agriculture and income source of the households of the study area. This study uses an in-depth interview form to interview the farmers living in the Sarayonu district of Konya province in Turkey to explore their vulnerability to climate change and its impacts on their households' income and poverty levels. The study results show that changes in water resources due to climate change impacts negatively affect the agriculture sector of Sarayonu, which alters the income sources of the households of the farmers. As a result, farmers cannot go for irrigated farming for many years and, consequently, do not have a proper harvest. Since climate change impacts reduce agricultural land productivity, farmers get low quality and less crop yield, leading the households into an income crisis.
Functional impact of multiple bleeding events in patients with conservatively treated spinal cavernous malformations
Authors: Rauschenbach Laurèl , Santos Alejandro N. , Gull Hanah H. , Rieß Christoph , Deuschl Cornelius , Schmidt Börge , Darkwah Oppong Marvin , Gembruch Oliver , Özkan Neriman , Jabbarli Ramazan , Wrede Karsten H. , Sure Ulrich , Dammann Philipp
Published: December 2022

OBJECTIVE

The aim of this study was to investigate the functional outcome in spinal cavernous malformation (SCM) patients with single or multiple intramedullary hemorrhagic events.

METHODS

SCM patients who were conservatively treated between 2003 and 2021 and had complete clinical baseline characteristics, an MRI data set, at least one SCM-related intramedullary hemorrhage (IMH), and at least one follow-up examination were included in this study. Functional status was assessed using the modified McCormick Scale score at diagnosis, before and after each bleeding event, and at the last follow-up.

RESULTS

A total of 45 patients were analyzed. Univariate analysis identified multiple bleeding events as the only statistically significant predictor for an unfavorable functional outcome at the last follow-up (OR 15.28, 95% CI 3.22–72.47; p < 0.001). Patients significantly deteriorated after the first hemorrhage (29.0%, p = 0.006) and even more so after the second hemorrhage (84.6%, p = 0.002). Multiple bleeding events were significantly associated with functional deterioration at the last follow-up (76.9%, p = 0.003). The time between the last IMH and the last follow-up did not influence this outcome.

CONCLUSIONS

IMH due to SCM is linked to functional worsening. Such outcomes tend to improve after each hemorrhage, but the probability of full recovery declines with each bleeding event.
A decrease in the neuroprotective effects of acute spinal cord decompression according to injury severity: introducing the concept of a ceiling effect
Authors: Prasse Tobias , Khaing Zin Z. , Cates Lindsay N. , Dewees Dane M. , Hyde Jeffrey E. , Bredow Jan , Hofstetter Christoph P.
Published: December 2022

OBJECTIVE

Acute traumatic spinal cord injury (tSCI) is followed by a prolonged period of secondary neuroglial cell death. Neuroprotective interventions, such as surgical spinal cord decompression, aim to mitigate secondary injury. In this study, the authors explore whether the effect size of posttraumatic neuroprotective spinal cord decompression varies with injury severity.

METHODS

Seventy-one adult female Long Evans rats were subjected to a thoracic tSCI using a third-generation spinal contusion device. Moderate and severe tSCI were defined by recorded impact force delivered to the spinal cord. Immediately after injury (< 15 minutes), treatment cohorts underwent either a decompressive durotomy or myelotomy. Functional recovery was documented using the Basso, Beattie, and Bresnahan locomotor scale, and tissue sparing was documented using histological analysis.

RESULTS

Moderate and severe injuries were separated at a cutoff point of 231.8 kdyn peak impact force based on locomotor recovery at 8 weeks after injury. Durotomy improved hindlimb locomotor recovery 8 weeks after moderate trauma (p < 0.01), but not after severe trauma (p > 0.05). Myelotomy led to increased tissue sparing (p < 0.0001) and a significantly higher number of spared motor neurons (p < 0.05) in moderate trauma, but no such effect was noted in severely injured rats (p > 0.05). Within the moderate injury group, myelotomy also resulted in significantly more spared tissue when compared with durotomy-only animals (p < 0.01).

CONCLUSIONS

These results suggest that the neuroprotective effects of surgical spinal cord decompression decrease with increasing injury severity in a rodent tSCI model.
HEAVY METALS IN SEA FOOD: METHOD VALIDATION AND EVOLUTION BY INDUCTIVELY COUPLED PLASMA MASS SPECTROMETRY IN ACCORDANCE WITH COMMISSION REGULATION (EC) 333/2007, 582/2016
Authors: Kumar Deepak , Kumar Vinay , Patnala Prem Kishore , Kumari Sangeeta
Published: December 2022

The goal of this study was to validate the analytical technique for determining the immediate development of lead (Pb), cadmium (Cd), mercury (Hg), and arsenic (As) in various Indian seafood products. According to Commission Regulation (EC) 333/2007, various marine foods, including crustaceans, cephalopods, and fish species, were employed for the validation of the developed method by ICP-MS. HNO3 and H2O2 were combined to prepare the sample during microwave digestion. Specificity/selectivity, linearity, LOD, LOQ, precision-repeatability and reproducibility, accuracy-recovery, robustness, and fitness studies were used to validate the approach. The maximum RSD value and Horrat value (HorRat) for the within-lab reproducibility for all analytes (Pb, Cd, Hg, and As) in marine food were 5% and 1 respectively. The mean recovery for all analytes examined at three spiking levels (0.5, 1 & 1.5 of the permitted limit) was between 92.67 and 107.33%.Whereas limit of detection (LOD) values for Pb, Cd, Hg and As were 0.018 µg/g, 0.032 µg/g, 0.031 µg/g and 0.034 mg/kg for repeatability 6% and < 1) showed that this analytical method could be used for the routine analysis of these four toxic metals in seafood with acceptable analytical performance in the laboratory
HgS NANOPARTICLES FROM CYCLODODECANONETHIOSEMICARBAZONE COMPLEX OF MERCURY AS SINGLE-SOURCE MOLECULAR PRECURSOR
Authors: George Jisha , Nath G. Rathika , Das S. Fasna , S. Aswathy  , K. Rajesh
Published: December 2022

Hg(II) complex of a new ligand cyclododecanonethiosemicarbazone (CDDTSC), was synthesized and characterized by spectral studies and elemental analysis. Synthesis of nano mercuric sulphide was done using the polyol method with glycerol as solvent. UV- Vis spectroscopy, PL, XRD, SEM, EDX, and TEM studies were done for characterization. Though Capping agents or surfactants were not used, highly crystalline, monodispersed HgS nanoparticles were obtained in good yield.
ANTIOXIDANT AND ANTIBACTERIAL ACTIVITIES OF PHYTOSYNTHESISED ZnOs BY Hibiscus tiliaceus LEAF EXTRACT AGAINST FOUR PATHOGENIC BACTERIA
Authors: Putri O.K. , H. Syafdhani  , Holilah  , A. Fadlan  , Y. Kusumawati  , M. Santoso  , D. Prasetyoko  , Achmad H.J.
Published: December 2022

The numerous benefits provided by Zinc oxide have attracted attention. Therefore, plenty of ZnO synthesis methods have been developed. This study reported the phytosynthesis of ZnOs by Hibiscus tiliaceus leaf extract, the characterization of phytosynthesised ZnOs, and their antibacterial and antioxidant activities. The H. tiliaceus leaf extract was prepared with distilled water and distilled water/ethanol mixtures at three different ratios. The characteristics of the phytosynthesised ZnOs were revealed by infrared spectroscopy, scanning electron microscopy, and X-ray diffraction. A spectrophotometric technique was enforced to investigate the antioxidant activity of phytosynthesised ZnOs and the total phenolic level of the extracts. The antibacterial activity was assayed against four pathogenic bacteria. The particle sizes of the phytosynthesised ZnOs were 46 nm to 273 nm with rod and hexagonal shapes. The highest DPPH free radical scavenging activity was shown by phytosynthesised ZnOs produced from extract with a ratio of aqua dest: ethanol, which was 1:1 (v/v). Strong antibacterial activity toward Staphylococcus epidermidis was displayed by phytosynthesised ZnOs compared to Staphylococcus aureus, Escherichia coli, and Salmonella typhi. The phenolic and flavonoid compounds of H. tiliaceus leaf extract affected the antioxidant activity of phytosynthesised ZnO. The inhibition zones of some phytosynthesised ZnOs were better than pharmaceutical-grade ZnO.
SENOLYTIC ACTIVITY EVALUATION OF CORIANDER (Coriandrum sativum L) PHYTOCONSTITUENTS: In-silico STUDY
Authors: I. Namirah  , Fadilah  , S. Dewi  , Lima F.V.I. de , Hardiany N.S.
Published: December 2022

Coriander phytoconstituent has pro-apoptotic and anti-inflammatory activities. This study evaluated the activity of Coriander phytoconstituent against the Senescent Cell Anti-Apoptotic Pathways (SCAPs) network nodes that serve as targets for senolytic drugs. Docking simulations were performed using Autodock Vina PyRx (v0.8), Autodock Tools 1.5.6, and visualized by the Discovery Studio Visualizer. The anti-apoptotic protein (BCL-XL, BCL-2, BCLW, and survivin) interaction network was obtained from String db.org. The flavonoid compounds showed good binding energy than non-flavonoid compounds. In flavonoid compounds, referring to the binding energy of standard drugs, rutin have a potent affinity to survivin with a binding energy of -7.47 kcal/mol. In addition, the binding energy of galangin-5-methylether, pectolinarigenin, luteolin, apigenin, and 5,6,7-trimethoxyflavone serve higher binding activity to BCL-XL in the ranges -7.73 – -8.64 kcal/mol. Meanwhile, pseudobaptigenin has an affinity to both proteins, survivin, and BCL-XL with the binding energy of -5.71 and -8.64 kcal/mol respectively. Hence, the coriander phytoconstituents could have the potential as a senolytic agent by interfering with the SCAPs, especially BCL-XL and survivin
EVALUATION OF ANTIMALARIAL ACTIVITY OF 4-METHOXYBENZOYL NEOLIGNAN DERIVATIVES THROUGH A MOLECULAR DOCKING STUDY AGAINST CHLOROQUINE-SENSITIVE AND -RESISTANT PROTEINS
Authors: S. Triono  , J. Jumina  , Pranowo H.D. , Sholikhah E.N.
Published: December 2022

In the present work, a molecular docking approach was conducted to investigate the antimalarial activity of neolignan derivatives with 4-methoxybenzoyl substituent (N1-N10) against chloroquine-sensitive and -resistant proteins. It was found that the neolignan derivatives were able to interact with the amino acid residues of Ala16, and Ser167/Tyr170 in the active site of the chloroquine-sensitive protein. On the other hand, the interactions of the neolignan derivatives with Arg59, Arg122, and Phe116/Ser120 residues were observed in the active site of the chloroquine-resistant protein. Most neolignan derivatives had stronger interaction than the native ligands in the active sites of both proteins. Among the evaluated neolignan derivatives, N9 and N8 compounds gave the strongest binding energy against the active sites of chloroquine-sensitive and -resistant proteins, respectively. These findings demonstrate that the presence of the nitro group in the neolignan structure is crucial for its inhibitory activity against chloroquine-sensitive and -resistant proteins.
SYNTHESIZE METAL-ORGANIC FRAMEWORKS FROM CHROMIUM METAL IONS AND PTCDA LIGANDS FOR METHYLENE BLUE PHOTODEGRADATION
Authors: N. Saridewi  , F. M. Azhar  , P. A. Abdillah  , A. Zulys  , S. Nurbayti  , L. Tulhusna  , A. Adawiah
Published: December 2022

A new photocatalyst-based metal-organic framework (MOFs) Cr-PTC was synthesized from chromium ion and sodium perylene-3,4,9,10-tetracarboxylate by the solvothermal method. This study aims to construct MOFs Cr-PTC and analyze their degradation photocatalytic activity against methylene blue under mercury lamp irradiation as the visible light source. XRD Spectrum exhibited MOFs Cr-PTC has intensity at a value of 2θ = 9.17°; 12.865°; 25.621°; and 27.85°. MOFs Cr-PTC has a narrow bandgap energy of 2.01 eV. MOFs Cr-PTC has good photocatalytic activity in methylene blue degradation under visible light irradiation at neutral pH with 87.22 mg/gram degradation capacity for 180 minutes. Species that play a dominant role in photocatalytic methylene blue degradation are hydroxyl radicals (•OH) and holes (h+ ) and are assisted by other species such as excited electrons (e- ) and superoxide radicals (•O2 - ).
A NOVEL UV SPECTROPHOTOMETRIC METHOD FOR SIMULTANEOUS ESTIMATION OF METOPROLOL TARTRATE AND ATORVASTATIN CALCIUM BASED ON ABSORBANCE CORRECTION PRINCIPLE
Authors: P. Shelar  , C. Nazareth  , R. Khorjuwenkar  , O. Pinto  , G. Kamat  , B. Naik
Published: December 2022

A novel, economical UV spectroscopic method for the simultaneous estimation of metoprolol and atorvastatin has been developed based on the absorbance correction principle. UV Spectrophotometric methods are rapid and economical and the absorbance correction principle is increasingly being employed for analysis as a convenient UV method of analysis. Methanol was used as solvent and water as diluent throughout the analysis. The wavelengths of 244.8 nm (λmax of atorvastatin) and 221.4 nm (λmax of metoprolol) were selected as λ1 and λ2 respectively. The method was validated as per ICH guidelines and was found to be accurate, precise, sensitive, and robust. The % assay value for the synthetic mixture was found to be 99.10% for metoprolol and 98.18% for atorvastatin which was within the acceptance value of 90 – 110%. The developed UV spectroscopic method is thus a valuable quality control tool in analysis.
ANTIBACTERIAL, CYTOTOXICITY, AND BIOSYNTHETIC GENE CLUSTER ANALYSIS OF CORAL-ASSOCIATED ACTINOBACTERIA FROM MENJANGAN BESAR ISLAND, KARIMUNJAWA NATIONAL PARK
Authors: T. Sibero Mada , H. Frederick Evan , Lubis Kristina , Wijayanti Diah P. , D. Haryanti  , P. Siswanto Anggun , Pringgenies Delianis , Murwani Retno , Igarashi Yasuhiro
Published: December 2022

Coral-associated actinobacteria have been abundantly reported for their biological properties, particularly as antimicrobial and anticancer agents. This study was carried out to investigate the potential of coral-associated actinobacteria as antibacterial and cytotoxic agents and analyze the biosynthetic gene clusters (BGCs) of the most remarkable isolate. Coral Porites cylindrica was collected from Menjangan Besar Island, Karimunjawa National Park, Indonesia. Based on the antibacterial screening, three out of fifteen isolates demonstrated the potential as antibacterial agents, such as CSM 11, CSM 13, and CSM 18. They were identified as Streptomyces rochei, S. xiamenensis, and S. albus, respectively. There were no crude extracts that demonstrated antibacterial activity. S. rochei CSM 11 from A11 medium showed a strong cytotoxic activity with an IC50 value of 4.50 µg/mL. The antiSMASH analysis described that S. rochei contains 33 clusters with various bioactive compounds.
ASSESSMENT OF ARSENIC, MERCURY, CADMIUM, LEAD, AND PALLADIUM IN ROPIVACAINE HYDROCHLORIDE MONOHYDRATE BY AN INDUCTIVELY COUPLED PLASMA MASS SPECTROMETER (ICPMS)
Authors: Pal Ashish Kumar , Sundararajan Raja
Published: December 2022

Ropivacaine hydrochloride monohydrate is prolonged acting amide local anesthesia. In its guidelines, the International Conference on Harmonization notes that elemental inorganic contaminants may enter active pharmaceutical ingredients and drug formulations from various causes. Arsenic, mercury, cadmium, mercury, and lead are examples of class 1 elements, which occur as inorganic contaminants that have hazardous effects on the human body. During the synthesis of ropivacaine hydrochloride monohydrate, palladium assisted as a catalyst. A simple, reliable, and reproducible inductively-coupled plasma mass-spectrometric (ICP-MS) method for assessing trace metals in ropivacaine hydrochloride monohydrate by open vessel acid digestion method was established and validated. All of the elements' limits were set by ICH Q3D.
Russia and Argentina: successes and difficulties of cooperation in challenging conditions
Authors: Gritsenko Ilona
Published: December 2022

The paper analyzes the current state of Russian-Argentine relations. The author considers the main lines of cooperation and trends of recent years and assesses the impact of the international crisis that began in 2022 on bilateral relations. Special attention is paid to the joint efforts of the two countries in the fight against Covid-19.
In recent years Russian-Argentine ties faced certain challenges. The risks associated with the need for Buenos Aires to conclude an agreement with the IMF, as well as the negative effects of the pandemic, did not lead to the negative dynamics of bilateral relations. On the contrary, cooperation strengthened and incorporated new areas of interaction, including healthcare. However, after the start of the special military operation of the Russian Federation the logistical and financial difficulties caused by the sanctions of the West had a negative impact on the Russian-Argentine cooperation and led to the suspension of individual projects.
System-Level Performance Evaluation for Multiple IoV Applications
Authors: Zheng Yinxiang , Shen Xu , Wang Jiayin , Wang Yafeng , Fan Zhuo
Published: December 2022

As the approach of fifth-generation (5G) era, the auto industry has received good development opportunities, which is one of the industry that has benefited most from 5G. Based on the powerful communication of 5G NR, all the information of vehicle running performance can be uploaded to the cloud. With the help of cloud computing, multiple internet of vehicles (IoV) applications come into existence. In this paper, the performance verification methods for typical IoV applications will be introduced in more details. Under each application scenario, we first determine a suitable traffic model, and further analyze how some key performance indicators (KPI) vary as the number of vehicles increases.