bluuebunny/crossref_metadata_2025 huggingface dataset:
Facile Synthesis of Super-Microporous Titania–Alumina with Tailored Framework Properties
Authors: Li Yongfeng , Su Jiaojiao , Li Guiping , Meng Xiufeng
Published: March 2020

Super-microporous material (pore size 1–2 nm) can bridge the pore size gap between the zeolites (<1 nm) and the mesoporous oxides (>2 nm). A series of super-microporous titania–alumina materials has been successfully prepared via a facile one-pot evaporation-induced self-assembly (EISA) strategy by different solvents using fatty alcohol polyoxyethylene ether (AEO-7) as the template. Moreover, no extra acid or base is added in our synthesis process. When titanium isopropylate is used as the titanium source, these materials exhibit high BET surface areas (from 275 to 396 m2/g) and pore volumes (from 0.14 to 0.18 cm3/g). The sample prepared using methanol as the solvent shows the largest Brunauer–Emmett–Teller (BET) surface area of 396 m2/g. When tetrabutyl titanate is used as the titanium source, these materials exhibit high BET surface areas (from 282 to 396 m2/g) and pore volumes (from 0.13 to 0.18 cm3/g). The sample prepared using ethanol as the solvent shows the largest BET surface area of 396 m2/g.
New Oscillation Results for Third-Order Half-Linear Neutral Differential Equations
Authors: Vidhyaa K. S. , Graef John R. , Thandapani E.
Published: March 2020

The main purpose of this paper is to obtain criteria for the oscillation of all solutions of a third-order half-linear neutral differential equation. The main result in this paper is an oscillation theorem obtained by comparing the equation under investigation to two first order linear delay differential equations. An additional result is obtained by using a Riccati transformation technique. Examples are provided to show the importance of the main results.
Chaos Suppression in Uncertain Generalized Lorenz–Stenflo Systems via a Single Rippling Controller with Input Nonlinearity
Authors: Lin Chih-Hsueh , Hu Guo-Hsin , Yan Jun-Juh
Published: March 2020

In this paper, a robust control design of chaos suppression is considered for generalized four-dimensional (4D) Lorenz–Stenflo systems subjected to matched/mismatched uncertainties and input nonlinearity. It is implemented by using rippling sliding mode control (SMC). A proportional-integral (PI) type scalar switching surface is designed such that the controlled dynamics in the sliding manifold becomes easy to analyze. Furthermore, only by using single rippling SMC even with input nonlinearity can we ensure the existence of the sliding mode for the controlled dynamics and suppress the chaotic behavior in a manner of rippling. Under the proposed control scheme, the chaos behavior in uncertain generalized 4D Lorenz–Stenflo systems subjected to mismatched uncertainties can be robustly suppressed to predictable bounds, which is not addressed in the literature. The numerical simulation results including matched/mismatched uncertainties and nonlinear inputs are presented to verify the robustness and validity of the rippling sliding mode controller.
Applying Visual Cryptography to Enhance Text Captchas
Authors: Yan Xuehu , Liu Feng , Yan Wei Qi , Lu Yuliang
Published: March 2020

Nowadays, lots of applications and websites utilize text-based captchas to partially protect the authentication mechanism. However, in recent years, different ways have been exploited to automatically recognize text-based captchas especially deep learning-based ways, such as, convolutional neural network (CNN). Thus, we have to enhance the text captchas design. In this paper, using the features of the randomness for each encoding process in visual cryptography (VC) and the visual recognizability with naked human eyes, VC is applied to design and enhance text-based captcha. Experimental results using two typical deep learning-based attack models indicate the effectiveness of the designed method. By using our designed VC-enhanced text-based captcha (VCETC), the recognition rate is in some degree decreased.
Optimal Shape and First Integrals for Inverted Compressed Column
Authors: Kacapor Enes , Atanackovic Teodor M. , Dolicanin Cemal
Published: March 2020

We study optimal shape of an inverted elastic column with concentrated force at the end and in the gravitational field. We generalize earlier results on this problem in two directions. First we prove a theorem on the bifurcation of nonlinear equilibrium equations for arbitrary cross-section column. Secondly we determine the cross-sectional area for the compressed column in the optimal way. Variational principle is constructed for the equations determining the optimal shape and two new first integrals are constructed that are used to check numerical integration. Next, we apply the Noether’s theorem and determine transformation groups that leave variational principle Gauge invariant. The classical Lagrange problem follows as a special case. Several numerical examples are presented.
On the Stability with Respect to H-Manifolds for Cohen–Grossberg-Type Bidirectional Associative Memory Neural Networks with Variable Impulsive Perturbations and Time-Varying Delays
Authors: Stamov Gani , Stamova Ivanka , Simeonov Stanislav , Torlakov Ivan
Published: March 2020

The present paper is devoted to Bidirectional Associative Memory (BAM) Cohen–Grossberg-type impulsive neural networks with time-varying delays. Instead of impulsive discontinuities at fixed moments of time, we consider variable impulsive perturbations. The stability with respect to manifolds notion is introduced for the neural network model under consideration. By means of the Lyapunov function method sufficient conditions that guarantee the stability properties of solutions are established. Two examples are presented to show the validity of the proposed stability criteria.
Nonlinear Integro-Differential Equations Involving Mixed Right and Left Fractional Derivatives and Integrals with Nonlocal Boundary Data
Authors: Ahmad Bashir , Broom Abrar , Alsaedi Ahmed , Ntouyas Sotiris K.
Published: March 2020

In this paper, we study the existence of solutions for a new nonlocal boundary value problem of integro-differential equations involving mixed left and right Caputo and Riemann–Liouville fractional derivatives and Riemann–Liouville fractional integrals of different orders. Our results rely on the standard tools of functional analysis. Examples are constructed to demonstrate the application of the derived results.
A Novel Ultrasonic Cleaning Tank Developed by Harmonic Response Analysis and Computational Fluid Dynamics
Authors: Tangsopa Worapol , Thongsri Jatuporn
Published: March 2020

The manufacturer of an ultrasonic cleaning tank (UCT) received advise from a customer to seek the cause to why the UCT could not clean their products effectively and develop a novel UCT to replace the conventional model. This UCT had a capacity of 10 L, a frequency of 28 kHz, four horn transducers, and a total power of 200 W. To resolve that problem and respond to customers’ needs, we presented new methods to develop the UCT using the harmonic response analysis (HRA) and computational fluid dynamics (CFD) to simulate the cleaning process which occurred within the UCT based on the actual conditions. Results from the HRA showed that the acoustic pressure in a problematic UCT was low, resulting in a smaller cleaning area, which was consistent with the results from the foil corrosion test, and thus caused the cleaning process to be ineffective. We developed a novel UCT with improved effectiveness by adjusting the design and adding a water circulation system. From the HRA, we were able to design the dimensions of the UTC and position of the transducer to be suitable to increase the acoustic pressure and cleaning area. CFD results enabled us to design proper inlet and outlet shapes, as well as simulate the water flow behavior to find the optimal cleaning condition so the novel UCT had a water circulation system that could eliminate the excess particles.
Tribological Characterization of Ni-Free Duplex Stainless Steel Alloys Using the Taguchi Methodology
Authors: Daraghma Hammam , Samad Mohammed Abdul , Toor Ihsan ul Haq , M. Abdallah Farid , Patel Faheemuddin
Published: March 2020

Duplex stainless steels (DSSs) exhibit excellent corrosion resistance and are being used in a variety of industrial applications. Reducing/eliminating the amount of nickel in such alloys will contribute significantly to its economic viability. Moreover, a well-established wear behavior for these alloys is also an essential development in most of their applications. Hence, in this work, the Taguchi technique was effectively implemented to investigate the effect of operating factors such as sliding speed and applied load on the wear behavior of different compositions of nickel-free DSSs. It was observed that the composition had a higher contribution of 33.66% to the wear rate (WR) and the contribution of the sliding speed to the coefficient of friction (COF) was found to be 68.17%. With a good agreement, a regression model was also developed to predict the WR and COF within a certain range of factors. Wear tests have also shown that the developed nickel-free DSS is a promising candidate in terms of wear resistance as compared to austenitic stainless steels (ASS).
Identification of Acoustic Characteristic Parameters and Improvement of Sound Absorption Performance for Porous Metal
Authors: Yang Xiaocui , Shen Xinmin , Duan Haiqin , Zhang Xiaonan , Yin Qin
Published: March 2020

Porous metal is widely used in the fields of sound absorption and noise reduction, and it is a critical procedure to identify acoustic characteristic parameters and to improve sound absorption performances. Based on the constructed theoretical sound absorption model and experimental data, acoustic characteristic parameters of the porous metal were identified through the cuckoo search identification algorithm, and their reliabilities were certified through comparing with these labeled parameters and further experimental validation. By adding the microperforated metal panel in front of the porous metal, a composite sound-absorbing structure was formed, which aimed to improve the sound absorption performance of the original porous metal by optimizing the parameters. Finite element simulation and a standing wave tube measurement were conducted to validate the effectiveness and practicability of the optimal composite sound-absorbing structure. Consistencies among theoretical predictions, simulation results, and experimental data proved the effectiveness of the identification and optimization method. When the target frequency ranges were 100–1000 Hz, 100–2000 Hz, 100–3000 Hz, and 100–4000 Hz. Actual average sound absorption coefficients of the optimal composite structures were 0.5154, 0.6369, 0.6770, and 0.7378, respectively, which exhibited the obvious improvements with a tiny increase in the occupied space and a small addition in weight.
Cannabis Microbiome and the Role of Endophytes in Modulating the Production of Secondary Metabolites: An Overview
Authors: Taghinasab Meysam , Jabaji Suha
Published: March 2020

Plants, including cannabis (Cannabis sativa subsp. sativa), host distinct beneficial microbial communities on and inside their tissues and organs, including seeds. They contribute to plant growth, facilitating mineral nutrient uptake, inducing defence resistance against pathogens, and modulating the production of plant secondary metabolites. Understanding the microbial partnerships with cannabis has the potential to affect the agricultural practices by improving plant fitness and the yield of cannabinoids. Little is known about this beneficial cannabis-microbe partnership, and the complex relationship between the endogenous microbes associated with various tissues of the plant, and the role that cannabis may play in supporting or enhancing them. This review will consider cannabis microbiota studies and the effects of endophytes on the elicitation of secondary metabolite production in cannabis plants. The review aims to shed light on the importance of the cannabis microbiome and how cannabinoid compound concentrations can be stimulated through symbiotic and/or mutualistic relationships with endophytes.
New Molecular Approach for the Detection of Kinetoplastida Parasites of Medical and Veterinary Interest
Authors: Medkour Hacène , Varloud Marie , Davoust Bernard , Mediannikov Oleg
Published: March 2020

Kinetoplastids are protozoa containing a range of ubiquitous free_living species–pathogens of invertebrates, vertebrates and even some plants. Some of them are causative agents of canine vector-borne diseases. Their diagnosis is often missing in a gold standard. Here, we proposed a molecular approach for the diagnosis and study of Kinetoplastida. The TaqMan qPCR assays target the following genes: 24Sa LSU of Kinetoplastida, 28S LSU of Leishmania/ Trypanosoma spp., 5.8S rRNA of Trypanosoma spp., 18S SSU of Leishmania spp., kinetoplast minicircle DNA (kDNA) of L. donovani complex and kDNA of L. infantum, were designed, validated for their sensitivity (Se) and specificity (Sp) in silico and in vitro using a panel of known DNAs. They were then used to screen 369 blood samples (358 dogs, 2 equids, 9 monkeys). In addition, new 28S LSU primer sets are presented to use for Kinetoplastida’s identification by PCR/sequencing. All qPCRs showed consistently high analytical sensitivities and reproducibility. They detect approximately 0.01 parasite/ mL blood for the kDNA based- qPCRs and at least a single cell-equivalent of rDNA for the other systems. Based on the sequencing results, after screening, Se and Sp were: 0. 919 and 0.971, 0.853 and 0.979, 1.00 and 0.987, 0.826 and 0.995 for all of Kinetoplastida, Leishmania/ Trypanosoma, Trypanosoma, Leishmania spp. specific qPCRs, respectively. kDNA based qPCRs were more sensitive and specific (Se: 1.00; Sp: 0.997). PCR/sequencing allowed the detection of Kinetoplastids in animal blood samples such as L. infantum, L. guyanensis, T. congolense, T. evansi and Bodo spp. The molecular approach proposed here is useful for epidemiological studies, fundamental research such as screening for new Kinetoplastida species, diagnosis and therapeutic follow-up. In addition, researchers are free to choose the molecular tools adapted to their aims.
Development of PCR-Based Detection System for Soft Rot Pectobacteriaceae Pathogens Using Molecular Signatures
Authors: Kabir Md Niamul , Taheri Ali , Dumenyo C. Korsi
Published: March 2020

Pectobacterium and Dickeya species, usually referred to as soft rot Enterobacteriaceae, are phytopathogenic genera of bacteria that cause soft rot and blackleg diseases and are responsible for significant yield losses in many crops across the globe. Diagnosis of soft rot disease is difficult through visual disease symptoms. Pathogen detection and identification methods based on cultural and morphological identification are time-consuming and not always reliable. A polymerase chain reaction (PCR)-based detection method with the species-specific primers is fast and reliable for detecting soft rot pathogens. We have developed a specific and sensitive detection system for some species of soft rot Pectobacteriaceae pathogens in the Pectobacterium and Dickeya genera based on the use of species-specific primers to amplify unique genomic segments. The specificities of primers were verified by PCR analysis of genomic DNA from 14 strains of Pectobacterium, 8 strains of Dickeya, and 6 strains of non-soft rot bacteria. This PCR assay provides a quick, simple, powerful, and reliable method for detection of soft rot bacteria.
Grinding Behaviors of Components in Heterogeneous Breakage of Coals of Different Ash Contents in a Ball-and-Race Mill
Authors: Duan Jin , Lu Qichang , Zhao Zhenyang , Wang Xin , Zhang Yuxin , Wang Jue , Li Biao , Xie Weining , Sun Xiaolu , Zhu Xiangnan
Published: March 2020

Coals used for power plants normally have different ash contents, and the breakage of coals by the ball-and-race mill or roller mill is an energy-intensive process. Grinding phenomena in mill of power plants is complex, and it is also not the same with ideal grinding tests in labs. The interaction among various coals would result in changes of grinding behaviors and energy consumption characterization if compared with those of single breakage. In this study, anthracite and bituminous coal of different ash contents were selected to be heterogeneously ground. Quantitation of components in products was realized using the relation between sulfur content of the mixture and mass yield of one component in the mixture. Product fineness t10 of the component was determined, and split energy was calculated on the premise of specific energy balance and energy-size reduction model by a genetic algorithm. Experimental results indicate that breakage rate and product fineness t10 of the mixture decrease with the increase of hard anthracite content in the mixture. Unlike the single breakage, t10 of anthracite in heterogeneous grinding is improved dramatically, and bituminous coal shows the opposite trend. The interaction between components results in the decrease of the specific energy of the mixture if compared with the mass average one of components in single breakage. Breakage resistance of hard anthracite decreases due to the addition of soft bituminous coal, and grinding energy efficiency of anthracite is also improved compared with that of single grinding.
Data-Driven Activities Involving Electronic Health Records: An Activity and Task Analysis Framework for Interactive Visualization Tools
Authors: Rostamzadeh Neda , Abdullah Sheikh S. , Sedig Kamran
Published: March 2020

Electronic health records (EHRs) can be used to make critical decisions, to study the effects of treatments, and to detect hidden patterns in patient histories. In this paper, we present a framework to identify and analyze EHR-data-driven tasks and activities in the context of interactive visualization tools (IVTs)—that is, all the activities, sub-activities, tasks, and sub-tasks that are and can be supported by EHR-based IVTs. A systematic literature survey was conducted to collect the research papers that describe the design, implementation, and/or evaluation of EHR-based IVTs that support clinical decision-making. Databases included PubMed, the ACM Digital Library, the IEEE Library, and Google Scholar. These sources were supplemented by gray literature searching and reference list reviews. Of the 946 initially identified articles, the survey analyzes 19 IVTs described in 24 articles that met the final selection criteria. The survey includes an overview of the goal of each IVT, a brief description of its visualization, and an analysis of how sub-activities, tasks, and sub-tasks blend and combine to accomplish the tool’s main higher-level activities of interpreting, predicting, and monitoring. Our proposed framework shows the gaps in support of higher-level activities supported by existing IVTs. It appears that almost all existing IVTs focus on the activity of interpreting, while only a few of them support predicting and monitoring—this despite the importance of these activities in assisting users in finding patients that are at high risk and tracking patients’ status after treatment.
Nanocelluloses and Related Materials Applicable in Thermal Management of Electronic Devices: A Review
Authors: Sato Kimiyasu , Tominaga Yuichi , Imai Yusuke
Published: March 2020

Owing to formidable advances in the electronics industry, efficient heat removal in electronic devices has been an urgent issue. For thermal management, electrically insulating materials that have higher thermal conductivities are desired. Recently, nanocelluloses (NCs) and related materials have been intensely studied because they possess outstanding properties and can be produced from renewable resources. This article gives an overview of NCs and related materials potentially applicable in thermal management. Thermal conduction in dielectric materials arises from phonons propagation. We discuss the behavior of phonons in NCs as well.
Shape Deformation in Ion Beam Irradiated Colloidal Monolayers: An AFM Investigation
Authors: Lotito Valeria , Karlušić Marko , Jakšić Milko , Tomić Luketić Kristina , Müller Ulrich , Zambelli Tomaso , Fazinić Stjepko
Published: March 2020

Self-assembly of colloidal monolayers represents a prominent approach to the fabrication of nanostructures. The modification of the shape of colloidal particles is essential in order to enrich the variety of attainable patterns which would be limited by the typical assembly of spherical particles in a hexagonal arrangement. Polymer particles are particularly promising in this sense. In this article, we investigate the deformation of closely-packed polystyrene particles under MeV oxygen ion irradiation at normal incidence using atomic force microscopy (AFM). By developing a procedure based on the fitting of particle topography with quadrics, we reveal a scenario of deformation more complex than the one observed in previous studies for silica particles, where several phenomena, including ion hammering, sputtering, chemical modifications, can intervene in determining the final shape due to the specific irradiation conditions. In particular, deformation into an ellipsoidal shape is accompanied by shrinkage and polymer redistribution with the presence of necks between particles for increasing ion fluence. In addition to casting light on particle irradiation in a regime not yet explored, we present an effective method for the characterization of the colloidal particle morphology which can be applied to describe and understand particle deformation in other regimes of irradiation or with different techniques.
Graphene Oxide Nanofiltration Membranes Containing Silver Nanoparticles: Tuning Separation Efficiency via Nanoparticle Size
Authors: Yang Kun , Huang Lin-jun , Wang Yan-xin , Du Ying-chen , Zhang Zhi-jie , Wang Yao , Kipper Matt J. , Belfiore Laurence A. , Tang Jian-guo
Published: March 2020

Three types of graphene oxide/silver nanoparticles (GO/AgNPs) composite membranes were prepared to investigate size-effect of AgNPs on nanofiltration ability. The size of AgNPs was 8, 20, and 33 nm, which was characterized by UV-visible spectroscopy and transmission electron microscopy. The morphology and structure of GO and GO/AgNPs composite membranes were characterized by atomic force microscopy, scanning electron microscopy, and X-ray diffraction. The filtration performance of membranes were evaluated on a dead-end filtration device. When the size of AgNPs is 20 nm, the GO/AgNPs composite membrane has the highest water flux (106.1 L m−2 h−1 bar−1) and rejection of Rhodamine B (RhB) (97.73%) among three types of composite membranes. The effect of feed concentration of dye solution and the flux of common solvent was also investigated. The mechanism was discussed, which demonstrated that both interlaying spacing and defect size influence the filtration ability of membrane, which is instructive to future study.
Triterpene Acids of Loquat Leaf Improve Inflammation in Cigarette Smoking Induced COPD by Regulating AMPK/Nrf2 and NFκB Pathways
Authors: Jian Tunyu , Ding Xiaoqin , Li Jiawei , Wu Yuexian , Ren Bingru , Li Jing , Lv Han , Chen Jian , Li Weilin
Published: March 2020

Cigarette smoking (CS) is believed to be an important inducement in the pathological development of chronic obstructive pulmonary disease (COPD), a progressive lung disease. Loquat is an Asian evergreen tree commonly cultivated for its fruit. Its leaf has long been used as an important material for both functional and medicinal applications in the treatment of lung disease in China and Japan. As the principal functional components of loquat leaf, triterpene acids (TAs) have shown notable anti-inflammatory activity. However, their protective activity and underlying action of mechanism on CS-induced COPD inflammation are not yet well understood. In the present study, male C57BL/6 mice were challenged with CS for 12 weeks, and from the seventh week of CS exposure, mice were fed with TAs (50 and 100 mg/kg) for 6 weeks to figure out the therapeutic effect and molecular mechanism of TAs in CS-induced COPD inflammation. The results demonstrate that TA suppressed the lung histological changes in CS-exposed mice, as evidenced by the diminished generation of pro-inflammatory cytokines, including interleukin 1β (IL-1β), IL-2, IL-6, and tumor necrosis factor α (TNF-α). Moreover, TA treatment significantly inhibited the malondialdehyde (MDA) level and increased superoxide dismutase (SOD) activity. In addition, TAs increased the phosphorylation of AMP-activated protein kinase (AMPK) and nuclear factor erythroid-2-related factor-2 (Nrf2) expression level, while inhibiting phosphorylation of nuclear factor kappa B (NFκB) and inducible nitric oxide synthase (iNOS) expression in CS-induced COPD. In summary, our study reveals a protective effect and putative mechanism of TA action involving the inhibition of inflammation by regulating AMPK/Nrf2 and NFκB pathways. Our findings suggest that TAs could be considered as a promising functional material for treating CS-induced COPD.
Iron, Zinc and Phytic Acid Retention of Biofortified, Low Phytic Acid, and Conventional Bean Varieties When Preparing Common Household Recipes
Authors: Hummel Marijke , Talsma Elise F. , Taleon Victor , Londoño Luis , Brychkova Galina , Gallego Sonia , Raatz Bodo , Spillane Charles
Published: March 2020

Biofortification is an effective method to improve the nutritional content of crops and nutritional intake. Breeding for higher micronutrient mineral content in beans is correlated with an increase in phytic acid, a main inhibitor of mineral absorption in humans. Low phytic acid (lpa) beans have a 90% lower phytic acid content compared to conventional beans. This is the first study to investigate mineral and total phytic acid retention after preparing common household recipes from conventional, biofortified and lpa beans. Mineral retention was determined for two conventional, three biofortified and two lpa bean genotypes. Treatments included soaking, boiling (boiled beans) and refrying (bean paste). The average true retention of iron after boiling was 77.2–91.3%; for zinc 41.2–84.0%; and for phytic acid 49.9–85.9%. Soaking led to a significant decrease in zinc and total phytic acid after boiling and refrying, whereas for iron no significant differences were found. lpa beans did not exhibit a consistent pattern of difference in iron and phytic acid retention compared to the other groups of beans. However, lpa beans had a significantly lower retention of zinc compared to conventional and biofortified varieties (p < 0.05). More research is needed to understand the underlying factors responsible for the differences in retention between the groups of beans, especially the low retention of zinc. Combining the lpa and biofortification traits could further improve the nutritional benefits of biofortified beans, by decreasing the phytic acid:iron and zinc ratio in beans.
The Relationship Between Healthy Eating Motivation and Protein Intake in Community-Dwelling Older Adults With Varying Functional Status
Authors: Rempe Hanna M. , Sproesser Gudrun , Hannink Anne , Skurk Thomas , Brandl Beate , Hauner Hans , Renner Britta , Volkert Dorothee , Sieber Cornel C. , Freiberger Ellen , Kiesswetter Eva
Published: March 2020

In older adults, the relationship between healthy eating motivation (HEM) and protein intake as key component of a healthy diet is poorly understood. Therefore, we investigate the association of HEM with (1) total protein intake and (2) intake of different protein sources in older adults with varying functional status. In this cross-sectional study including 250 adults (≥70 years), we assessed HEM with “The Eating Motivation Survey” and protein intake by 7-day food records. In addition, gender, age, Body Mass Index (BMI), energy intake and functional status were considered. Regression analyses revealed that HEM was neither related to total (β = −0.02; p = 0.723) nor to relative protein intake (β = 0.04; p = 0.370). Notwithstanding this, participants with stronger HEM showed lower intake of protein from meat and meat products (β = −0.14; p = 0.018), higher intake of overall plant-based protein (β = 0.11; p = 0.032), protein from fruit and vegetables (β = 0.20; p = 0.002) and from pulses, nuts an seeds (β = 0.16; p = 0.016). Our findings suggest HEM as a valuable indicator for intake of distinct protein sources. However, since HEM is not related to total protein intake, the importance of sufficient protein consumption should be emphasized by promoting healthy eating, regardless of self-perceived HEM.
A Blind Man Leads a Blind Man? Personalised Nutrition-Related Attitudes, Knowledge and Behaviours of Fitness Trainers in Hungary
Authors: Kiss Anna , Pfeiffer Laura , Popp József , Oláh Judit , Lakner Zoltán
Published: March 2020

It is well-documented that fitness trainers could play an important role in the nutrition-related behaviour of their clients based on their personalised nutrition-related counselling activities, but there are considerable concerns all over the world about the level of their knowledge to become nutritional coaches. In the framework of the current study based on qualitative (focus-group interviews) and quantitative (questionnaire and analysis of responses by multivariable methods, as well as structural equation modelling) methods, it has been proven that (1) theoretically, both the trainers and the dietitians acknowledge the importance of cooperation in the optimisation of coaching efficiency and advisory work due to some “professional jealousness” and differences in professional background, as well as in culture, so it is hard to find a common platform for cooperation, especially in market segments characterised by relative low levels of purchasing power; (2) due to lack of regulation, there is a high heterogeneity of professional competences of trainers in general and their nutritional competences, in particular; (3) the majority of trainers do not have an objective picture on his/her effective nutritional knowledge, and they often offer a much wider scope of services (e.g., nutritional counselling for clients with chronic diseases) which are well beyond their professional knowledge and (4) the dietary guidelines have not become an integral part of professional knowledge, even at the level of specialists. To improve the current—in some cases, dangerous—situation, the following steps should be taken: (1) enhancement of the level of professional qualification of future trainers, integrating the practice-oriented approaches and emphasising the role of teamwork by simulation-based practices; (2) highlighting in a clear way the professional and ethical boundaries of the activities of trainers and (3) working out an efficient incentive system for the continuous professional development of trainers.
Association between Body Fatness and Vitamin D3 Status in a Postmenopausal Population
Authors: Vázquez-Lorente Héctor , Molina-López Jorge , Herrera-Quintana Lourdes , Gamarra-Morales Yenifer , López-González Beatriz , Planells Elena
Published: March 2020

Vitamin D is a micronutrient that plays a key role in phosphocalcic metabolism. The postmenopausal population presents a risk of deficiency in this vitamin due to hormonal alterations which, in the case of obesity, would be exacerbated. The objective was to assess the status of vitamin D in a postmenopausal population and determine the relationship of 25-hydroxivitamin D [25(OH)D] and its metabolites with anthropometric parameters. The study included 78 healthy postmenopausal women aged from 44 to 76. The nutrient intake assessment was carried out using the 24 h reminder (R24h). 25(OH)D was analyzed using ultra-high-performance liquid chromatography (UHPLC). A total of 80% and 68% of the women studied did not reach sufficient values of 25(OH)D and 25-hydroxivitamin D3 [25(OH)D3], respectively, which was inversely correlated with Body Mass Index (BMI) (r = −0.25, p = 0.04), hip perimeter (r = −0.26 and r = −0.24, all p < 0.05), arm circumference (r = −0.29, p = 0.01) and fat mass (r = −0.28 and r = −0.26, all p < 0.05). 25(OH)D3 is the metabolite that contributed most to this association. In conclusion, 25(OH)D3 levels are related to anthropometric parameters in the postmenopausal women in this study, confirming insufficient status in the majority of the population. Approach strategies are necessary to correct and avoid this risk in order to ensure future quality of life.
Functional Biomarkers for the Selenium Status in a Human Nutritional Intervention Study
Authors: Müller Sandra M. , Dawczynski Christine , Wiest Johanna , Lorkowski Stefan , Kipp Anna P. , Schwerdtle Tanja
Published: March 2020

Soils in Germany are commonly low in selenium; consequently, a sufficient dietary supply is not always ensured. The extent of such provision adequacy is estimated by the optimal effect range of biomarkers, which often reflects the physiological requirement. Preceding epidemiological studies indicate that low selenium serum concentrations could be related to cardiovascular diseases. Inter alia, risk factors for cardiovascular diseases are physical inactivity, overweight, as well as disadvantageous eating habits. In order to assess whether these risk factors can be modulated, a cardio-protective diet comprising fixed menu plans combined with physical exercise was applied in the German MoKaRi (modulation of cardiovascular risk factors) intervention study. We analyzed serum samples of the MoKaRi cohort (51 participants) for total selenium, GPx activity, and selenoprotein P at different timepoints of the study (0, 10, 20, 40 weeks) to explore the suitability of these selenium-associated markers as indicators of selenium status. Overall, the time-dependent fluctuations in serum selenium concentration suggest a successful change in nutritional and lifestyle behavior. Compared to baseline, a pronounced increase in GPx activity and selenoprotein P was observed, while serum selenium decreased in participants with initially adequate serum selenium content. SELENOP concentration showed a moderate positive monotonic correlation (r = 0.467, p < 0.0001) to total Se concentration, while only a weak linear relationship was observed for GPx activity versus total Se concentration (r = 0.186, p = 0.021). Evidently, other factors apart from the available Se pool must have an impact on the GPx activity, leading to the conclusion that, without having identified these factors, GPx activity should not be used as a status marker for Se.
Volumetric Calibration Refinement of a Multi-Camera System Based on Tomographic Reconstruction of Particle Images
Authors: Bruecker Christoph , Hess David , Watz Bo
Published: March 2020

The calibration of a multi-camera system for volumetric measurements is a basic requirement of reliable 3D measurements and object tracking. In order to refine the precision of the mapping functions, a new, tomographic reconstruction-based approach is presented. The method is suitable for Volumetric Particle Image Velocimetry (PIV), where small particles, drops or bubbles are illuminated and precise 3D position tracking or velocimetry is applied. The technique is based on the 2D cross-correlation of original images of particles with regions from a back projection of a tomographic reconstruction of the particles. The off-set of the peaks in the correlation maps represent disparities, which are used to correct the mapping functions for each sensor plane in an iterative procedure. For validation and practical applicability of the method, a sensitivity analysis has been performed using a synthetic data set followed by the application of the technique on Tomo-PIV measurements of a jet-flow. The results show that initial large disparities could be corrected to an average of below 0.1 pixels during the refinement steps, which drastically improves reconstruction quality and improves measurement accuracy and reliability.
Exploring the Partonic Phase at Finite Chemical Potential in and out-of Equilibrium
Authors: Soloveva O. , Moreau P. , Oliva L. , Voronyuk V. , Kireyeu V. , Song T. , Bratkovskaya E.
Published: March 2020

We study the influence of the baryon chemical potential μ B on the properties of the Quark–Gluon–Plasma (QGP) in and out-of equilibrium. The description of the QGP in equilibrium is based on the effective propagators and couplings from the Dynamical QuasiParticle Model (DQPM) that is matched to reproduce the equation-of-state of the partonic system above the deconfinement temperature T c from lattice Quantum Chromodynamics (QCD). We study the transport coefficients such as the ratio of shear viscosity η and bulk viscosity ζ over entropy density s, i.e., η / s and ζ / s in the ( T , μ ) plane and compare to other model results available at μ B = 0 . The out-of equilibrium study of the QGP is performed within the Parton–Hadron–String Dynamics (PHSD) transport approach extended in the partonic sector by explicitly calculating the total and differential partonic scattering cross sections based on the DQPM and the evaluated at actual temperature T and baryon chemical potential μ B in each individual space-time cell where partonic scattering takes place. The traces of their μ B dependences are investigated in different observables for symmetric Au + Au and asymmetric Cu + Au collisions such as rapidity and m T -distributions and directed and elliptic flow coefficients v 1 , v 2 in the energy range 7.7 GeV ≤ s N N ≤ 200 GeV.
Upscaling the Surveillance of Tick-Borne Pathogens in the French Caribbean Islands
Authors: Gondard Mathilde , Delannoy Sabine , Pinarello Valérie , Aprelon Rosalie , Devillers Elodie , Galon Clémence , Pradel Jennifer , Vayssier-Taussat Muriel , Albina Emmanuel , Moutailler Sara
Published: March 2020

Despite the high burden of vector-borne disease in (sub)tropical areas, few information are available regarding the diversity of tick and tick-borne pathogens circulating in the Caribbean. Management and control of vector-borne disease require actual epidemiological data to better assess and anticipate the risk of (re)emergence of tick-borne diseases in the region. To simplify and reduce the costs of such large-scale surveys, we implemented a high-throughput microfluidic real-time PCR system suitable for the screening of the main bacterial and parasitic genera involved in tick-borne disease and potentially circulating in the area. We used the new screening tool to perform an exploratory epidemiological study on 132 adult specimens of Amblyomma variegatum and 446 of Rhipicephalus microplus collected in Guadeloupe and Martinique. Not only the system was able to detect the main pathogens of the area—Ehrlichia ruminantium, Rickettsia africae, Anaplasma marginale, Babesia bigemina and Babesia bovis—but the system also provided evidence of unsuspected microorganisms in Caribbean ticks, belonging to the Anaplasma, Ehrlichia, Borrelia and Leishmania genera. Our study demonstrated how high-throughput microfluidic real-time PCR technology can assist large-scale epidemiological studies, providing a rapid overview of tick-borne pathogen and microorganism diversity, and opening up new research perspectives for the epidemiology of tick-borne pathogens.
In Memoriam: Edward “Ned” Lally
Authors: Balashova Nataliya
Published: March 2020

On February 11, 2019, we lost a colleague and friend Dr [...]
Aggregatibacter, a Low Abundance Pathobiont That Influences Biogeography, Microbial Dysbiosis, and Host Defense Capabilities in Periodontitis: The History of a Bug, and Localization of Disease
Authors: Fine Daniel H. , Schreiner Helen , Velusamy Senthil Kumar
Published: March 2020

Aggregatibacter actinomycetemcomitans, the focus of this review, was initially proposed as a microbe directly related to a phenotypically distinct form of periodontitis called localized juvenile periodontitis. At the time, it seemed as if specific microbes were implicated as the cause of distinct forms of disease. Over the years, much has changed. The sense that specific microbes relate to distinct forms of disease has been challenged, as has the sense that distinct forms of periodontitis exist. This review consists of two components. The first part is presented as a detective story where we attempt to determine what role, if any, Aggregatibacter plays as a participant in disease. The second part describes landscape ecology in the context of how the host environment shapes the framework of local microbial dysbiosis. We then conjecture as to how the local host response may limit the damage caused by pathobionts. We propose that the host may overcome the constant barrage of a dysbiotic microbiota by confining it to a local tooth site. We conclude speculating that the host response can confine local damage by restricting bacteremic translocation of members of the oral microbiota to distant organs thus constraining morbidity and mortality of the host.
Exploring Pharmacy Technician Roles in the Implementation of an Appointment-Based Medication Synchronization Program
Authors: Renfro Chelsea , Coulter Davis , Ly Lan , Fisher Cindy , Cardosi Lindsay , Wasson Mike , Hohmeier Kenneth C.
Published: March 2020

The objective of this study was to qualitatively explore the role of pharmacy technicians in the implementation of an appointment-based model (ABM) medication synchronization program. The purposeful sampling of technicians working within six different locations of a supermarket chain pharmacy in Mississippi and Tennessee was carried out, and the technicians were interviewed between January and April 2018. A semi-structured interview guide was developed based on the Consolidated Framework for Implementation Research (CFIR). Questions gathered information around pharmacy technician demographics and CFIR domains (process, inner setting, outer setting and intervention characteristics). Interviews were audiotaped and transcribed. Two members of the research team performed thematic content analysis. Six full-time, certified pharmacy technicians with 8.3 ± 2.7 years of experience were interviewed. Findings suggest that including hands-on experience with program software is needed during training to successfully implement ABM. A barrier to implementation was the time needed to complete ABM tasks as compared to other tasks. Although some barriers exist regarding implementation, technicians believe that overall, this program has positive benefits for patients. Results from this study signify that ABM implementation can be challenging. Better ABM portal integration with the pharmacy patient profile and appropriate workforce budgeting are key to continued success.
Proteomics-Based Detection of Immune Dysfunction in an Elite Adventure Athlete Trekking Across the Antarctica
Authors: Nieman David C. , Groen Arnoud J. , Pugachev Artyom , Simonson Andrew J. , Polley Kristine , James Karma , El-Khodor Bassem F. , Varadharaj Saradhadevi , Hernández-Armenta Claudia
Published: March 2020

Proteomics monitoring of an elite adventure athlete (age 33 years) was conducted over a 28-week period that culminated in the successful, solo, unassisted, and unsupported two month trek across the Antarctica (1500 km). Training distress was monitored weekly using a 19-item, validated training distress scale (TDS). Weekly dried blood spot (DBS) specimens were collected via fingerprick blood drops onto standard blood spot cards. DBS proteins were measured with nano-electrospray ionization liquid chromatography tandem mass spectrometry (nanoLC-MS/MS) in data-independent acquisition (DIA) mode, and 712 proteins were identified and quantified. The 28-week period was divided into time segments based on TDS scores, and a contrast analysis between weeks five and eight (low TDS) and between weeks 20 and 23 (high TDS, last month of Antarctica trek) showed that 31 proteins (n = 20 immune related) were upregulated and 35 (n = 17 immune related) were downregulated. Protein–protein interaction (PPI) networks supported a dichotomous immune response. Gene ontology (GO) biological process terms for the upregulated immune proteins showed an increase in regulation of the immune system process, especially inflammation, complement activation, and leukocyte mediated immunity. At the same time, GO terms for the downregulated immune-related proteins indicated a decrease in several aspects of the overall immune system process including neutrophil degranulation and the antimicrobial humoral response. These proteomics data support a dysfunctional immune response in an elite adventure athlete during a sustained period of mental and physical distress while trekking solo across the Antarctica.
International Collaboration in Open Access Publications: How Income Shapes International Collaboration
Authors: Cary Michael , Rockwell Taylor
Published: March 2020

Does the rise of open access journals change the way researchers collaborate? Specifically, since publishing in open access journals requires a publication fee, does income affect how researchers form international collaborations? To answer this question, we create a new data set by scraping bibliographic data from Multidisciplinary Digital Publishing Institute (MDPI) journals. Using the four income group classifications from the World Bank Analytical Classifications, we find that researchers from low-income nations are more likely to form international collaborations than researchers from wealthier nations. This result is verified to be significant using a series of pairwise Kolmogorov–Smirnov tests. We then study which nations most frequently form international collaborations with other nations and find that the USA, China, Germany, and France are the most preferred nations for forming international collaborations. While most nations prefer to form international collaborations with high-income nations, some exceptions exist, where a nation most often forms international collaborations with a nearby nation that is either an upper-middle-income or lower-middle-income nation. We further this analysis by showing that these results are apparent across the six different research categories established in the Frascati Manual. Finally, trends in publications in MDPI journals mirror trends seen in all journals, such as the continued increase in the percentage of published papers involving international collaboration.
Annually Laminated Lake Sediments—Recent Progress
Authors: Tylmann Wojciech , Zolitschka Bernd
Published: March 2020

The collection of papers entitled “Annually Laminated Lake Sediments” illustrates the recent progress made in varved sediment research and highlights the variety of methodological approaches and research directions used. The contributions cover the monitoring of modern sediment fluxes using sediment traps, geochronological and sedimentological analyses of varves, multi-proxy investigations, including geochemical and biological proxies, as well as spatiotemporal analyses based on multi-core studies supported by satellite images. The scientific issues discussed the influences of hydroclimatological phenomena on short-term changes in sediment flux, the relationships between biogeochemical processes in the water column and the formation of varves, the preservation of environmental signals in varves, and possibilities of synchronizing varved records with other high-resolution environmental archives.
Improving Fly Ash Brightness with Carbon and Iron Oxide Removal
Authors: Song Helong , Fan Huiming , Gao Hang-tian , Liu Jian-an , Mou Hongyan
Published: March 2020

In this paper, the brightness of fly ash is improved by carbon removal by heating and iron-containing oxides removal by acid treatment using a two-step method to realize the application of fly ash as filler or coating in the future, which not only increases the range of resource utilization of fly ash, but also reduces dust pollution. The modification results show that the brightness of fly ash reaches the maximum value of 38.27% ISO (Brightness unit) after decarburization by heating at 600 °C. On this basis, the Box–Benhnken design scheme is adopted to optimize the brightening process for removing iron-containing oxides in fly ash. Finally, when the concentration of hydrochloric acid is 15%, the acid leaching time is 0.75 h, the reaction temperature is 74 °C, and the brightness of fly ash can eventually increase to 43.92% ISO.