bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of a Biomathematical Modeling Software Tool for the Prediction of Risk in Flight Schedules Compared Against Incidence of Fatigue Reports
Authors: Devine Jaime K. , Choynowski Jake , Hursh Steven R.
Published: January 2025

Background: Modeling tools should be tested against real-world outcomes to confirm their predictive ability compared to random chance. Insights is an analytical tool within the biomathematical modeling software SAFTE-FAST that identifies work patterns that consistently result in elevated fatigue risk. This study investigated the ability of Insights to correctly identify duties with an associated fatigue report using previously collected flight schedule and report data. Methods: Planned and completed flight roster schedules were analyzed using SAFTE-FAST Insights after the rosters had been flown. Fatigue reports were independently linked to planned and completed schedules at the duty level. Odds ratio (OR) analysis investigated the ability of Insights to predict which duties would be linked to a fatigue report. Differences in duties were compared using a one-way analysis of variance (ANOVA) and a two-sample t-test. Results: There were 157 fatigue reports out of 78,061 planned duties and 235 fatigue reports out of 82,612 completed duties. Insights had 3.04 odds of correctly identifying fatigue reports in planned duties but 0.41 odds for completed duties. Discussion: Insights showed good odds of correctly identifying a fatigue report duty using planned schedules but poor odds of identifying a fatigue report duty from completed schedules. Completed duties started later in the day and were shorter in duration than planned duties. Day-of-operations schedule changes may have reduced the fatigue risk in response to the fatigue reports.
Effect of Body-Weight-Based Resistance Training on Balance Ability and Fear of Falling in Community-Dwelling Older Japanese Women
Authors: Liu Zhenyue , Sawada Shuji , Deng Pengyu , Naito Hisashi , Machida Shuichi
Published: January 2025

Background: This study aimed to investigate the effects of a 12-week body-weight-based resistance training program on balance ability and fear of falling in community-dwelling older women. Methods: Twenty-three older women were assigned to either an intervention group that performed the low-load resistance training with slow movement using the body weight (LRT group; n = 12) or a control group (CON group; n = 11). The LRT group participated in the exercise session twice weekly for 12 weeks, while the CON group maintained their daily routine. The 30 s chair stand test (CS-30) was applied to measure lower-extremity muscle strength, balance ability was evaluated using one-leg standing tests with eyes open (OLST-O) and closed (OLST-C), and fear of falling among all participants was assessed using the Falls Efficacy Scale International (FES-I) before (pre) and after (post) the intervention. A two-way analysis of variance with repeated measures [group (LRT and CON) × time (pre and post)] was carried out to evaluate the intervention effects. Results: Significant interactions were observed in the CS-30 (F = 9.503, p < 0.01, ηp2 = 0.312), OLST-O (F = 5.211, p < 0.05, ηp2 = 0.199), and OLST-C (F = 5.257, p < 0.05, ηp2 = 0.200), though significant simple main effects from pre to post were observed only in the LRT group. The CS-30 scores (pre: 19.8 ± 3.8 times, post: 25.5 ± 5.6 times; p < 0.001), OLST-O time (pre: 78.8 ± 35.8 s, post: 96.2 ± 29.9 s; p < 0.01), and OLST-C time (pre: 10.2 ± 5.9 s, post: 17.4 ± 12.2 s; p < 0.01) were improved before and after the intervention. However, a significant interaction was not observed in FES-I (F = 1.335, p = 0.261, ηp2 = 0.06). Conclusions: The 12-week body-weight-based resistance training program enhanced lower-extremity muscle strength and balance ability but did not lessen the fear of falling in community-dwelling older women. The study findings offer relevant information for fall prevention in older adults.
Contrasting Trajectories in Adolescent Pro-Environmentalism: Qualitative Differences Between “Engagers” Versus “Disengagers”
Authors: Brown Jaida , Krettenauer Tobias
Published: January 2025

The present study is a qualitative expansion of pre-existing quantitative research. Two groups of teenagers from a previous longitudinal study were specifically targeted, namely those who demonstrated extraordinary increases in their pro-environmental engagement from 13 to 17 years (called “Engagers”) and those who showed the opposite trajectory, that is, a marked decrease in pro-environmental behavior, reminiscent of an adolescent dip (called “Disengagers”). Nineteen participants (equally distributed across the engagers and disengagers categories) took part in semi-structured interviews that explored participants’ relationships with nature over their adolescent years, communication about environmental issues in the context of family, peers and school, as well as media influences. All interviewees described memorable nature experiences in childhood and adolescence as important to them, and all were growing up in family households where parents had established basic routines of sustainability behavior. All participants had access to a wealth of media information about environmental sustainability (and lack thereof). However, they largely differed in what they made out of it. For the group of disengagers, environmental concerns moved more and more into the background as other themes, goals, and projects came to the forefront over the adolescent period (e.g., graduation, establishing an educational and occupational career, establishing lasting peer relationships). In contrast, engagers actively expanded their environmental engagement over time. As a consequence, this engagement became increasingly independent from family, peer and school contexts. Ultimately, it was the process of engagement and disengagement itself that accounted for the different trajectories that were targeted in the present study. The study points out that it is not possible to understand the developmental context for pro-environmentalism as a factor that operates independently from the individual person. Teenagers create the contexts that influences their pro-environmental engagement as much as they are influenced by them.
A Comprehensive Assessment of PM2.5 and PM10 Pollution in Cusco, Peru: Spatiotemporal Analysis and Development of the First Predictive Model (2017–2020)
Authors: Warthon Julio , Zamalloa Ariatna , Olarte Amanda , Warthon Bruce , Miranda Ivan , Zamalloa-Puma Miluska , Ccollatupa Venancia , Ormachea Julia , Quispe Yanett , Jalixto Victor , Cruz Doris , Salcedo Roxana , Valencia Julieta , Mio-Diaz Mirian , Ingles Ruben , Warthon Greg , Tello Roberto , Uscca Edwin , Candia Washington , Chura Raul , Rubio Jesus , Alvarez Modesta
Published: January 2025

This study presents the first comprehensive assessment of air pollution by PM2.5 and PM10 in the city of Cusco, aiming to determine atmospheric pollution levels, characterize air quality, and develop predictive models. The research, conducted during 2017–2020, systematically evaluated particulate matter (PM) contamination using a high-volume sampler (HiVol ECOTEC 3000) installed at 18 monitoring sites distributed across five urban districts. Multiple linear regression (MLR) models were developed and evaluated, incorporating meteorological, seasonal, and temporal variables under two approaches: direct linear (Model 1) and logarithmic transformation (Model 2). The model evaluation employed R², RMSE, MAE, MAPE, IOA, and CV statistical indicators. The results revealed concentrations significantly exceeding WHO guideline values, with PM2.5 ranging between 41.10 ± 3.2 μg/m3 (2020) and 82.01 ± 5.1 μg/m3 (2018), while PM10 values ranged from 45.07 ± 2.8 μg/m3 (2020) to 72.35 ± 4.3 μg/m3 (2017). A notable reduction was observed during 2020, attributable to COVID-19 pandemic restrictions. The Air Quality Index (AQI) indicated predominantly “Unhealthy” and “Very Unhealthy” levels during 2017–2018, improving to “Unhealthy for Sensitive Groups” in 2020. MLR models achieved maximum efficiency using logarithmic transformation, obtaining R² = 0.98 (p < 0.001) for PM2.5 in the 2020 rainy season and R² = 0.44 (p < 0.001) for PM10 in the 2018 annual model. These findings demonstrate the existence of nonlinear relationships between pollutants and predictor variables in Cusco’s atmospheric basin.
Tetracycline Degradation by Persulfate Assisted by Fe and N Co-Doped Biochar Derived from Spent Mushroom Substrate for Sustainability: Effect of Pyrolysis Temperature
Authors: Xu Shimiao , Chang Jianning , Liu Yuan , Wei Bingbing , Zhang Haibo , Oh Kokyo , Cheng Caiping , Cheng Hongyan
Published: January 2025

Mushroom production is increasing rapidly worldwide, raising public concern about the contamination effects of spent mushroom substrates (SMS). Preparation of Fe–N-doped biochar (Fe-N-BC) from SMS as a raw material for catalytic degradation of antibiotics in water may be an effective and sustainable solid waste treatment. However, there is limited information available. This study investigated the effect and potential mechanism of SMS-based Fe-N-BC prepared at 300, 600, and 900 °C to catalyze persulfate (PS) for tetracycline (TC) removal. The results indicated that the catalytic performance of Fe-N-BC was significantly enhanced with increasing pyrolysis temperature. Notably, Fe-N-BC prepared at 900 °C exhibited high TC removal efficiency, with 95% TC removal at 120 min. This might be closely related to the fact that the Fe-N-BC prepared at high temperatures had more Fe oxides and active sites. Adsorption and radical and non-radical pathways were the main mechanisms for TC removal by Fe-N-BC/PS systems, especially the contribution of SO4·−. By identifying the degradation products, three possible pathways of TC degradation were proposed, and the toxicity of the degradation intermediates was evaluated. The results of the reusability analysis indicated that the Fe-N-BC prepared at 900 °C had good potential for practical application, and the TC removal rate still reached 76%, even after five cycles. These findings provide valuable reference information for solid waste resources’ sustainable utilization and the remediation of antibiotic-contaminated water.
Deep Reinforcement Learning-Based Real-Time Energy Management for an Integrated Electric–Thermal Energy System
Authors: Shuai Qiang , Yin Yue , Huang Shan , Chen Chao
Published: January 2025

Renewable energy plays a crucial role in achieving sustainable development and has the potential to meet humanity’s long-term energy requirements. Integrated electric–thermal energy systems are an important way to consume a high proportion of renewable energy. The intermittency and volatility of integrated electric–thermal energy systems make solving energy management optimization problems difficult. Thus, this paper proposes an energy management optimization method for an integrated electric–thermal energy system based on the improved proximal policy optimization algorithm, which effectively mitigates the problems of the traditional heuristic algorithms or mathematical planning methods with low accuracy and low solving efficiency. Meanwhile, the proposed algorithm enhances both the convergence speed and overall performance compared to the proximal policy optimization algorithm. This paper first establishes a mathematical model for the energy management of an integrated electric–thermal energy system. Then, the model is formulated as a Markov decision process, and a reward mechanism is designed to guide the agent to learn the uncertainty characteristics of renewable energy output and load consumption in the system through historical data. Finally, in the case study section, the proposed algorithm reduces the average running cost by 2.32% compared to the other algorithms discussed in this paper, thereby demonstrating its effectiveness and cost-efficiency.
Empowering WBANs: Enhanced Energy Efficiency Through Cluster-Based Routing and Swarm Optimization
Authors: S Sureshkumar , A. V Santhosh Babu , S Joseph James , R Priya
Published: January 2025

Wireless body area networks (WBANs) have great potential to supply society with vital technical services, but the low power of network nodes severely hampers their development. To solve this problem, Energy-Efficient, a low-power cluster-based routing system intended for precise biological data gathering in WBANs, is presented in this study. This approach comprises three main stages: data aggregation, cluster head (CH) selection, and cluster creation. The suggested approach balances biosensor energy and optimizes energy usage by utilizing the modified snake swarm optimization algorithm (MSSOA) for routing and the adaptive binary bird swarm optimization algorithm (ABBSOA) for cluster formation and CH selection. The suggested technique outperforms the most recent WBAN routing protocols, including MT-MAC, ALOC, DHCO, and M-GWO, by using a power-balancing routing tree and considering biosensor distance and remaining energy. The experimental results demonstrate that the proposed ABBSOA-MSSOA model achieves a jitter protocol value of 0.3 ms at 100 nodes, a buffer occupancy ratio of 2.5%, a cluster lifetime of 600 s, a cluster building time of 12.2 s, an energy consumption of 42 mJ, a communication overhead of 8.3%, a packet delivery ratio of 98.2%, and an average end-to-end delay of 25 ms compared to other existing methods.
Hyers–Ulam and Hyers–Ulam–Rassias Stability for a Class of Fractional Evolution Differential Equations with Neutral Time Delay
Authors: Alharbi Kholoud N.
Published: January 2025

In this paper, we demonstrate that neutral fractional evolution equations with finite delay possess a stable mild solution. Our model incorporates a mixed fractional derivative that combines the Riemann–Liouville and Caputo fractional derivatives with orders 0<α<1 and 1<β<2. We identify the infinitesimal generator of the cosine family and analyze the stability of the mild solution using both Hyers–Ulam–Rassias and Hyers–Ulam stability methodologies, ensuring robust and reliable results for fractional dynamic systems with delay. In order to guarantee that the features of invariance under transformations, such as rotations or reflections, result in the presence of fixed points that remain unchanging and represent the consistency and balance of the underlying system, fixed-point theorems employ the symmetry idea. Lastly, the results obtained are applied to a fractional order nonlinear wave equation with finite delay with respect to time.
Enabling Digital Capabilities with Technologies: A Multiple Case Study of Manufacturing Supply Chains in Disruptive Times
Authors: Ardolino Marco , Bino Anna , Ciano Maria Pia , Bacchetti Andrea
Published: January 2025

In the rapidly changing digital economy, manufacturing companies are under growing pressure to adopt new approaches to business management by developing digital capabilities. This research explores the role of digital technologies in enabling these capabilities, using the Digital Capability Model (DCM) as a guiding framework. While previous research often focused on theoretical perspectives, this study operationalizes the DCM by identifying specific applications of digital technologies that enhance business processes. Through a multiple case study methodology, eight manufacturing companies were examined to assess how digital technologies foster the development of digital capabilities. The case studies provide practical insights into the application of these technologies and their impact on organizational resilience and competitiveness, particularly in response to global disruptions such as the COVID-19 pandemic. Our findings reveal that certain technologies are more promising than others for enhancing digital capabilities and that their strategic implementation significantly improves a company’s ability to navigate uncertainty. Embracing digital transformation not only mitigates operational risks but also ensures sustainable competitive advantages in an increasingly volatile and complex environment. This research bridges the gap between theory and practice, offering actionable insights for managers to strategically develop and leverage digital capabilities for long-term success.
Does Clostridium Perfringens Epsilon Toxin Mimic an Auto-Antigen Involved in Multiple Sclerosis?
Authors: Gougeon Marie-Lise , Seffer Valérie , Hoxha Cezarela , Maillart Elisabeth , Popoff Michel R.
Published: January 2025

Multiple sclerosis (MS) is a chronic immune-mediated neurological disorder, characterized by progressive demyelination and neuronal cell loss in the central nervous system. Many possible causes of MS have been proposed, including genetic factors, environmental triggers, and infectious agents. Recently, Clostridium perfringens epsilon toxin (ETX) has been incriminated in MS, based initially on the isolation of the bacteria from a MS patient, combined with an immunoreactivity to ETX. To investigate a putative causative role of ETX in MS, we analyzed the pattern of antibodies reacting to the toxin using a sensitive qualitative assay. This prospective observational study included one hundred patients with relapsing remitting multiple sclerosis (RRMS), all untreated, and ninety matched healthy controls. By assessing the isotypic pattern and serum concentration of ETX-reacting antibodies, our study shows a predominant IgM response over IgG and IgA antibody responses both in MS patients and controls, and significantly higher levels of IgM reacting to ETX in MS patients compared to the control group. A longitudinal follow-up of ETX-specific antibody response in a subgroup of MS patients did not show any correlation with disease evolution. Overall, these unexpected findings are not compatible with a specific recognition of ETX by serum antibodies from MS patients. They rather argue for a cross immunological reactivity with an antigen, possibly an autoantigen, mimicking ETX. Thus, our data argue against the hypothesis of a causal relationship between C. perfringens ETX and MS.
Flood Evacuation in Informal Settlements: Application of an Agent-Based Model to Kibera Using Open Data
Authors: Butters Olivia , Dawson Richard J.
Published: January 2025

Flood incident management involves taking actions to save lives and reduce damages during a flood. Agent-based modelling tools have recently been developed to simulate the dynamic interactions between people and floodwater as a flood event unfolds. To date, these have only been applied in locations with a wealth of data, relying upon bespoke local or national datasets. Although informal settlements have a concentration of vulnerable people and are often more exposed to natural hazards, data availability is often limited, posing challenges for planning and implementing flood incident management actions. In this study, a model that was first applied in the UK is adapted and applied to simulate flood evacuations in Kibera, a densely populated informal settlement in Nairobi. Although data quality limits some of the model’s potential, the results reproduce patterns of observed behaviour. Evacuation shelters in the Northwest, North, and Northeast are shown to perform best. A major exit route to the South, a bridge crossing, and a river path are shown to be especially prone to congestion during evacuations. This paper reports on the first application of an agent-based model to an informal settlement, Kibera. The demonstration is an important step towards an operational tool for flood incident management planning in informal settlements around the world.
Influenza Immunization in Very-Low-Birth-Weight Infants: Epidemiology and Long-Term Outcomes
Authors: Dammann Marie-Theres , Kraft Hannah , Stichtenoth Guido , Hanke Kathrin , Zemlin Michael , Soler Wenglein Janina , Ricklefs Isabell , Herz Alexander , Humberg Alexander , Viemann Dorothee , Engels Geraldine , Kopp Matthias Volkmar , Brinkmann Folke , Fortmann-Grote Carsten , Göpel Wolfgang , Herting Egbert , Härtel Christoph , Fortmann Ingmar ,   on behalf of the German Neonatal Network
Published: January 2025

Background: Very-low-birth-weight infants (VLBWIs; birth weight < 1500 g) are at an increased risk of complicated influenza infection, which frequently includes pneumonia, encephalitis or even death. Data on influenza immunization and its outcome in VLBWIs are scarce. This study aimed to provide epidemiological data on influenza immunization for German VLBWIs and hypothesized that immunization would protect VLBWIs from infection-mediated neurodevelopmental impairment and preserves lung function at early school age. Methods: In this observational population-based German Neonatal Network (GNN) study, infants born between 2009 and 2015 were invited to partake in a 6-year follow-up investigation including lung function and developmental testing. Uni- and multivariate analyses were performed to evaluate the clinical characteristics and outcomes of influenza-immunized VLBWIs compared to non-immunized VLBWIs. Results: Influenza immunization was performed in 871 out of the 3358 VLBWIs (26%) with six-year follow-up. Immunized infants were characterized by a low gestational age and higher rates of morbidity, particularly bronchopulmonary dysplasia. Although early immunization showed no safety signals and had protective effects on the long-term risk of bronchitis (OR: 0.2; CI: 0.1–0.6; p = 0.002), most VLBWIs (88.0%) were unimmunized in their first influenza season. Conclusions: Influenza immunization was not associated with improved lung function (forced expiratory volume in one second and forced vital capacity) or a better neurocognitive outcome (intelligence quotient and strengths and difficulties questionnaire) at early school age. In Germany, only one quarter of 6-year-old VLBWIs were immunized against influenza, particularly those born <28 gestational weeks and/or BPD. Specific influenza immunization guidelines that define evidence-based recommendations are needed for this vulnerable group.
COVID-19 Vaccine Hesitancy Among Various Segments of the Population in Turkey: A Literature Review
Authors: Okay Sezer
Published: January 2025

Vaccine hesitancy, which refers to the reluctance to be vaccinated, poses a major risk to public health in preventing infectious diseases. This hesitancy has been evident for many years, especially regarding childhood vaccines. The main factors contributing to this hesitancy include religious or personal beliefs, concerns about safety and efficacy, and desire to receive more information from healthcare providers. This literature review examines hesitancy regarding COVID-19 vaccines in different population segments in Turkey. Hesitancy rates and reasons in the general population and specific groups such as pregnant women, parents, healthcare workers and students were presented based on published research articles. Approximately half of the Turkish population declared their hesitancy towards COVID-19 vaccines. A negative correlation was found between vaccine hesitancy and health literacy. The relationship between COVID-19 vaccine hesitancy and religiosity was also investigated. Age is another factor affecting this vaccine hesitancy. Older age was shown to be correlated with positive attitude towards COVID-19 vaccination. Moreover, participants with positive attitudes towards other vaccines, those with chronic diseases and those with a personal history of COVID-19 were more likely to have positive perceptions of COVID-19 vaccines. Higher life satisfaction and non-smoking status were associated with a higher likelihood of COVID-19 vaccine acceptance. Increased scientific data on the efficacy and side effects of COVID-19 vaccines and more information from healthcare professionals would likely reduce the hesitancy towards COVID-19 vaccines.
An Efficient Coordinated Observer LQR Control in a Platoon of Vehicles for Faster Settling Under Disturbances
Authors: Murugan Nandhini , Mohamed Ismail Mohamed Rabik
Published: January 2025

The rapid proliferation of vehicles globally presents significant challenges to road transportation efficiency and safety, including accidents, emissions, energy utilization, and road management. Autonomous vehicle platooning emerges as a promising solution within intelligent transportation systems, offering benefits like reduced fuel consumption and emissions, and optimized road use. However, implementing autonomous vehicle platooning faces obstacles such as stability under disturbances, safety protocols, communication networks, and precise control. This paper proposes a novel control strategy coordinated Kalman observer–Linear Quadratic Regulator (CKO-LQR) to ensure platoon formation stability in the presence of disturbances. The disturbances considered include vehicle movements, sensor noise, and communication delays, with the leading vehicle’s movement serving as the commanding signal. The proposed controller maintains a constant inter-gap distance between vehicles despite the disturbances utilizing a coordinated Kalman observer to estimate preceding vehicle movements. A comparative analysis with conventional PID controllers demonstrates superior performance in terms of faster settling times and robustness against disturbances. This research contributes to enhancing the efficiency and safety of autonomous vehicle platooning systems.
La incorporación de la prueba digital en el derecho procesal ecuatoriano
Authors: Imaicela Revilla Jackson Alejandro , Alvarado Ajila Lissette Amelia
Published: January 2025

La incorporación de pruebas digitales en el Derecho Procesal ecuatoriano plantea retos y oportunidades significativos. Ante esto, el objetivo de la investigación fue analizar la influencia de la incorporación de pruebas digitales en el Derecho Procesal ecuatoriano, en comparación con Colombia y China. La investigación jurídica se enmarcó en un enfoque cualitativo, bajo el paradigma interpretativo, con un diseño exploratorio-descriptivo, basado en el análisis de fuentes documentales y normativas. Los resultados indican que en Ecuador se permite la admisión de documentos digitalizados con la misma validez que los físicos, esto implica desafíos en términos de autenticidad y seguridad. En contraste, los marcos normativos de Colombia y China ofrecen un equilibrio más robusto entre flexibilidad y seguridad jurídica. Se concluye que es necesario establecer marcos normativos más rigurosos para la recolección y preservación de pruebas digitales en Ecuador. Las prácticas de estos países pueden servir como modelo para lograr esta mejora
El impacto de las políticas públicas en los derechos laborales de los inmigrantes en Ecuador
Authors: García Cedeño Nayeli Salomé , Chinga Velásquez Melanie Nahomy , Cruz Marte Israel Antonio
Published: January 2025

La migración a lo largo del tiempo ha sido un fenómeno riesgoso, pero ha sido asimilado y tolerado socialmente desde tiempos antiguos hasta la actualidad; individuos han inmigrado en búsqueda de mejor calidad de vida. El objetivo de analizar las políticas públicas del Ecuador en materia de derechos laborales de los trabajadores inmigrantes, para determinar su impacto. El método utilizado de enfoque mixto, tipo descriptivo, fundamentado en técnicas de análisis de documentos y la exegesis, revisión bibliográfica y el análisis histórico-lógico en relación con las políticas públicas que impactan en los derechos laborales de los inmigrantes en Ecuador. Los resultados señalan que, Ecuador ha fortalecido su sistema de protección internacional, implementando mecanismos para determinar la condición de refugiado y promoviendo su integración socioeconómica. Se concluye que, aunque el gobierno ecuatoriano parece tener una actitud positiva hacia los inmigrantes, aún existen barreras, tales como actos de discriminación, remuneración inferior al salario mínimo e inaccesibilidad al seguro social para los inmigrantes.
Importancia de las redes sociales para el crecimiento y éxito de las pymes en la ciudad de Chihuahua
Authors: Ivonne Ferrá Santiesteban Paola , Terrazas César Báez , Sánchez Brenda Guadalupe Burciaga , Rodriguez Jaime Aguirre , Bencomo Myrna Isela García , Bolivar Marisol Priscila Palafox
Published: January 2025

Las redes sociales pueden ser de gran impacto convirtiéndose en una herramienta de comunicación entre clientes, proveedores y empleados capaces de abrir nuevos mercados y hacer que las empresas sean más competitivas. En esta investigación, se describe la importancia de las redes sociales para el crecimiento de pequeñas y medianas empresas de la ciudad de Chihuahua, Chihuahua. El método del estudio fue con diseño etnográfico donde las técnicas de recolección y análisis de la información fueron observaciones con apoyo de los datos del INEGI e investigaciones ya realizadas con resultados de análisis cuantitativo, este censo nos da información caracterizada, así conocemos el total de establecimientos en el estado de Chihuahua, teniendo 57.7% establecimientos formales, y 42.3% de los negocios son informales. Las redes sociales en el camino correcto pueden ayudar al máximo crecimiento de las empresas, se debe ser claro y plasmar los objetivos que se desean alcanzar eso sí, para no perder el rumbo, pues una mala administración puede dañar la imagen y disminuir la producción.
Uma sequência didática para o estudo da análise combinatória no ensino médio
Authors: Coimbra Jhonatan Filipe Neves , Alves Manuela Lima Guimarães , Costa Acylena Coelho
Published: January 2025

Este artigo apresenta uma investigação cujo objetivo foi verificar as contribuições da aplicação de uma Sequência Didática para o processo de ensino e aprendizagem da Análise Combinatória. O embasamento teórico foi centrado na perspectiva de Zabala (1998), Dolz e Schneuwly (2004) e Cabral (2017), além da perspectiva de Gonçalves (2020), Ambrozi, (2017) e Silva (2017).  Na elaboração da Sequência Didática foram abordados três conceitos iniciais da Análise Combinatória, a saber: o Princípio Fundamental da contagem, a operação fatorial e a operação permutação. A pesquisa é de caráter qualitativo, na qual a Sequência Didática, organizada em 3 blocos cada um com 5 atividades, foi aplicada em uma turma de 30 alunos da 2ª série do ensino médio em uma escola estadual de Belém. Os resultados apontam que embora alguns conceitos não tenham sido assimilados pelos alunos, percebeu-se os discentes mais reflexivos e críticos mediante as questões. Concluiu-se que a Sequência Didática favorece a autonomia dos alunos e auxilia o professor na estruturação mais efetiva dos conteúdos.
Trombocitopenia imune idiopática – relato de caso
Authors: Dias Maria Teresa Araujo , Martins Luiza Paganini Tavares , Castro Alysson Victor de Oliveira , Izoton Igor , Café Beatriz Almeida , Rego Maria Carolina Dias , Soares Lívia de Paula
Published: January 2025

O presente estudo visa relatar e discutir o caso de uma paciente idosa com múltiplas comorbidades, em contexto de internação prolongada, que apresenta subitamente quadro de plaquetopenia e sangramento grave. Depois de iniciada investigação, o caso acaba tendo como principal hipótese diagnóstica a trombocitopenia imune idiopática. Os distúrbios da coagulação podem ser causadores de quadros clínicos críticos, com elevada morbidade e mortalidade caso não tratados corretamente. Por serem doenças relativamente raras, é necessário um conhecimento sólido sobre diagnóstico e manejo inicial. As informações contidas neste trabalho foram obtidas a partir de revisão do prontuário, anamnese, exame físico do paciente e revisão da literatura.
Insuficiência cardíaca isquemica e trombose pulmonar secundárias ao uso de esteróides anabolizantes - um relato de caso
Authors: Castro Alysson Victor de Oliveira , Martins Luiza Paganini Tavares , Dias Maria Teresa Araujo , Izoton Igor , Filho Carlos Eduardo Dourado Lemos , Soares Eduardo Tito dos Reis
Published: January 2025

O uso de esteroides anabolizantes androgênicos (EAA) está associado a diversas complicações cardiovasculares, como redução da função sistólica e diastólica do ventrículo esquerdo, levando à insuficiência cardíaca. Esses efeitos podem persistir mesmo após a suspensão do uso. Os EAA aumentam o volume de placas coronarianas, favorecem o desequilíbrio entre colesterol LDL e HDL, elevam o risco de aterosclerose e hipertensão, e estão relacionados a eventos trombóticos, como tromboembolismo e infarto do miocárdio. O caso clínico descrito ilustra as complicações graves, destacando a importância do reconhecimento precoce do uso de EAA para prevenir desfechos adversos. A conscientização em ambientes de risco, como academias, é essencial para reduzir o uso indiscriminado e seus impactos na saúde pública.
Rastreio de déficit cognitivo e seu impacto na qualidade de vida de idosos residentes em instituição de longa permanência em Poços de Caldas-MG
Authors: Gurgel Antonio Carlos Gouvea do Amaral , Pereira Thais Nastrini , Alvisi Teresa Cristina
Published: January 2025

O envelhecimento populacional é uma das mais significativas mudanças do século XXII. Estudos projetam que o número de idosos até 2050 chegará a 2,1 bilhões de pessoas no mundo. Esse cenário é repleto de múltiplos tipos de envelhecimento, podendo ser acompanhada por altos níveis de doenças crônicas quanto por saúde e bem-estar. O declínio cognitivo aparece como um dos acontecimentos fisiológicos do envelhecimento, no entanto são alterações que podem reduzir a funcionalidade e independência do indivíduo e, quando aliado à falta de assistência social e de políticas públicas para a população geriátrica, acaba por levar a institucionalização do idoso. O idoso institucionalizado, por sua vez, acaba por apresentar um expressivo nível de sedentarismo, carência afetiva e perda de autonomia, situação muitas vezes desencadeadora de depressão. Este projeto tem como finalidade realizar um levantamento de como o déficit cognitivo é capaz de impactar na qualidade de vida de idosos residentes em instituições de longa permanência no município de Poços de Caldas, MG. A pesquisa baseia-se na aplicação de questionários como Mini Exame do Estado Mental, Escala de Katz modificada por Likert, Escala de Depressão Geriátrica de Yesavage e WHOQOL-bref, para avaliação da cognição, capacidade de execução de atividades básicas de vida diária, depressão e a qualidade de vida dos participantes. Após a aplicação dos questionários, os dados obtidos foram submetidos à análise estatística visando comprovar as hipóteses levantadas.
Fratura naso-órbito-etmoidal: relato de caso
Authors: Gregório João Anderval , Sá Rodrigo Tavares de , Brasil Richard Presley Silva Lima , Ribeiro Isabela Gomes de Sena , Sobrinho Luiz Carlos Pires , Rodrigues Melquisedeque Paiva , Belle Júlia Ribeiro Lima , Vilela Thiago Freitas Prado
Published: January 2025

As fraturas naso-órbito-etmoidais são fraturas complexas que, em muitos casos, envolvem fraturas no osso frontal. Por serem fraturas de difícil resolução é imprescindível que seja feito a tomografia computadorizada. A partir desse momento, podemos classificar a fratura naso-órbito-etmoidal e selecionar a técnica cirúrgica mais adequada. O presente trabalho tem como objetivo apresentar um relato de caso de um paciente de 43 anos, sexo masculino, vítima de um acidente automobilístico, diagnosticado com as seguintes fraturas: fratura na parede anterior do osso frontal, fraturas bilaterais no complexo naso-órbito-etmoidal, fratura dos ossos próprios nasais, incluindo o septo nasal, e fratura blow-out à esquerda. Diante disso, após a avaliação dos dados clínicos, exames complementares e planejamento minucioso feito pela equipe, foi realizada a cirurgia para redução das fraturas. Dessa forma, foi realizado o acesso coronal e, posteriormente, a fixação de uma placa de adaptação de 1,5 mm, em forma de T, para fixação da parede anterior do seio frontal. Também foi fixado uma placa de adaptação de 1,5 mm, em forma de L, no processo frontonasal e frontal da maxila. Por fim, foi feito à estabilização do tendão cantal medial por meio de fiação intranasal. Sendo, esta, fixada na placa de adaptação em L. Após o procedimento cirúrgico foram realizados novos exames de imagem e proservação do paciente, concluindo que a conduta escolhida se mostrou eficiente e assertiva.
Correlação dos dados Ergoespirométricos, Força Respiratória e Quadríceps em pacientes COVID Longa
Authors: Júnior Odonis Rocha , Harmatiuk Hisllana Bohaenko , Clemente Pedro Augusto , Martins Hilana Rickli Fiuza , Bini Ana Carolina Dorigoni , Bonini Juliana Sartori , Daniel Christiane Riedi
Published: January 2025

Objetivos: Realizar a avaliação funcional em jovens com Covid longo após 6 a 12 meses e correlacionar os dados ergoespirométricos aos valores de força muscular de quadríceps e respiratórios. Metodologia: Um estudo transversal foi conduzido com pacientes covid longo, onde foi avaliado a força e a ativação muscular de quadríceps, a força muscular inspiratória e a capacidade cardiorrespiratória. Resultados: No total, 20 participantes foram avaliados, com idade média de 29,11±12,6. Foi encontrada correlação Os produtos obtidos coletados Volume de Consumo de Oxigênio (VO2) x RMS (Root Mean Square - Eletromiografia) – R=0,532 e p= 0,016, Volume Pulmonar (VE) x Capacidade Vital Forçada (CVF) - R=0,669 e p= 0,01, Volume Pulmonar (VE) x Volume Expiratório Forçado no primeiro segundo (VEF1) - R=0,656 e p= 0,02, Volume Pulmonar (VE) x Índice de força respiratória (S-INDEX) - R=0,522 e p= 0,018, VE x PIF - R=0,519 e p= 0,019, Volume Pulmonar(VE) x Força Muscular de Quadríceps - R=0,577 e p= 0,011 e Volume Pulmonar (VE) x RMS (Root Mean Square - EMG) - R=0,581 e p= 0,007 apresentaram moderada correlação entre os dados de força muscular de quadríceps e de musculatura respiratória. Conclusão: Ainda que apresente pequeno impacto em pacientes com a manifestação leve, a COVID-19 causa disfunções crônicas no sistema cardiopulmonar e muscular, sendo necessário medidas que auxiliem na recuperação completa.
Treinamento e educação para segurança do anestesiologista em procedimentos intervencionistas envolvendo radiação
Authors: Torres Andreza Munik Araújo Alves , Gonçalves Elielson Felix , Almeida Bruna Surlane Rodrigues de , Lira Ashlley Kessy De Sousa , Carvalho Ivna Naftali de , Santos Patrícia Silva dos , Muniz André Victor Teixeira , Almeida Luciana Gomes Vieira de , Melo Ghislayne Martins de , Nogueira Adna Cândido , Carvalho Marina Medeiros Araújo , Nunes Isabella Alves , Martins Filipe Moreira , Carvalho Maria Luar de Oliveira , Oliveira Marcos Vinícius Guimarães
Published: January 2025

Introdução: A proteção radiológica é um tópico de extrema relevância à saúde ocupacional de qualquer profissional exposto à radiação em suas funções. Apesar disso, poucos estudos brasileiros abordam esse tema no contexto da anestesiologia. Objetivo: Sistematizar as informações a respeito da exposição à radiação e proteção radiológica para médicos anestesiologistas. Metodologia: Foi realizado uma revisão integrativa da literatura, na qual onze artigos se adequaram aos critérios de inclusão e exclusão, estando divididos em três categorias principais: medição da exposição à radiação, conhecimento e prática profissional e recomendações acerca da proteção radiológica direcionadas à anestesiologistas. Resultados e discussão: Sumariamente, os resultados indicaram que a manutenção da distância do equipamento que produz radiação, o uso de proteção adequada como coletes de chumbo, escudos protetores, óculos e protetores de tireoide, além do monitoramento da dose recebida, são as formas mais eficazes de proteção. Apesar disso, o dosímetro e equipamentos de proteção permanecem subutilizados. Conclusão: Apesar da existência de normativas de radioproteção, ressalta-se a necessidade de treinamento e formação de campanhas educativas para anestesiologistas, visando a prevenção de danos a saúde desses profissionais. Além disso, percebe-se a necessidade de mais estudos de proteção radiológica focados na anestesiologia, em especial no contexto brasileiro.
Carcinoma ameloblástico mandibular: diagnóstico, abordagem e desafios na gestão de uma rara neoplasia odontogênica
Authors: Machado Isabela Cristina Pires , Vasconcelos Rodrigo Abdalla de , Nascimento Jonas Gonzaga do , Vasconcelos Luisa Ribeiro Ramos Abdalla de , Vasconcelos Mariana Ribeiro Ramos Abdalla de , Rodrigues Marisa de Campos , Faria Vitória Aguiar de , Silva Natália Vicente de Souza
Published: January 2025

O carcinoma ameloblástico (CA) é uma neoplasia odontogênica maligna rara, representando menos de 2% dos tumores odontogênicos. Este artigo relata o caso de um homem de 41 anos, atendido com uma massa ulcerovegetante no assoalho da boca, evoluindo com disfagia, perda de peso e comprometimento do estado geral. A tomografia revelou lesão óssea multiloculada, expansiva e com comprometimento de partes moles. O paciente foi submetido à mandibulectomia parcial, com diagnóstico histopatológico de carcinoma ameloblástico moderadamente diferenciado, sem invasão linfovascular ou perineural. Após cinco anos de acompanhamento, o paciente permanece livre de doença. Este relato contribui para a compreensão dos achados clínicos, radiográficos e histopatológicos do CA, destacando a importância de uma abordagem cirúrgica com margens livres e seguimento prolongado para controle adequado da doença.
Sexual behavior of young boars supplemented with two Zn source
Authors: Ortega Yasmin Guadalupe de Loera , Artiga Carlos García , González Jesús. A. Guevara , Yagüe Antonio Palomo , Redondo Beatriz Isabel , García-Contreras Adelfa del Carmen
Published: January 2025

Zinc is an essential nutrient involved in a wide range of biological functions, particularly in aspects of reproduction, including fertility and sex hormone production. The aim of the present study was to evaluate different amounts and types of Zn on ejaculate collection time and training behaviour of young boars. Were used fifteen young males (York-Landrace), 6.8-months-old with 120 Kg body weight (BW) were randomly assigned to three treatments. Boars received a basal diet (BD=T1) corn-soybean without addition of Zn. The BD were supplemented according to their required concentrations in each treatment (T2=BD+ZnSO4 150ppm and T3=BD+ZnMET 150ppm). The boars were trained 30 min per day to mount and mate dummy in a special pen for four weeks. The reaction time and duration of ejaculation were measured, finding that there was no effect (P>0.05) between the observed sexual behavior variables (NTS = Number of training session; FM=Number false mounts (mounting dummy but dismounting before allowing a collection of semen); EM=Effective mounts (mounting dummy and complete collection of semen); DE=Duration of ejaculation in minutes. Treatment x Time interaction (P>0.064) in the variable NTS, decreased when using ZnMET 150ppm with respect to ZnSO4 150ppm, in addition to increasing the Interval between training (days); (P=0.013), also a longer DE (6.49min). It can be concluded, that the results of our experiment demonstrate a positive effect when using ZnMET 150ppm on sexual behavior and some variables assessed during training boars.
The role of the antecedent precipitation index on runoff of semi arid catchment (North-West Algeria)
Authors: Mehaiguene Madjid , Touhari Fadhila , Zouidi Mohamed
Published: January 2025

Precipitation (P) is used primarily to approximate soil moisture in a watershed. In the present paper, relation between antecedent precipitation index (API), evaporation and soil water content is studied. The main purpose is to study the role of the Antecedent Precipitation Index on runoff (shape of the hydrograph) in the semi-arid catchment of Arib Ebda located in northwestern Algeria, an area of 269 km2 and 77% low permeability. For the case study, we have plotted hydrographs of the max flow in time Qmax = f (t) and hyetograms rainfall in time P = f (t), calculated runoff, asymmetry and flattening runoff coefficients. We studied the relationship between different hydrological variables (API5days – rainfall (P) -max flow (Qmax) – runoff depth (Lr) –runoff coefficient (Kr) using principal component analysis (PCA). The results of this analysis indicate that there is a good relationship between the API5days and the max flow, and a strong relationship between the max flow and the rainfall, as well as between the rainfall and the runoff depth (Lr). Finally, we have established a total rainfall - runoff diagram based on the runoff coefficient.
Pastoral structure in Tindouf’s argan grove (Algerian Sahara)
Authors: Réda Kechairi , Mohammed Ould Safi , Mohamed Boughalia , Benamar Bemahioul
Published: January 2025

Our argan heritage is found in its natural state in the north-west of the wilaya of Tindouf, in the south-west of the Algerian Sahara. The argan tree, a xerothermophilous species, is a sylvo-pastoral vocation. It is currently suffering from prolonged aridity and anthropogenic damage, specifically overgrazing. This study analysed the pastoral structure. Grazing is dominated by goats (85%) compared with camels (13%). Once the source of water supply became available through the creation of boreholes within the Arganeraie reserve, the Saharawi nomads changed their way of life from nomadic pastoralists to sedentary pastoralists. In times of prolonged drought, when fodder resources have become very scarce, they reduce the number of head and divide the grazing land into small units. It should be noted here that there is temporary uncontrolled grazing, which increases immediately after rainfall, which re-extinguishes the grass and, as a result, reduces the renewal capacity of the argan tree plant formation.
India’s Empowerment of Women: A Critical Examination
Authors: Hanumanthaiah BH
Published: January 2025

Because of the traditional patriarchal nature of our culture, women are viewed as second-class citizens in the political, social, and economic arenas. However, women equality and empowerment has always been a key issue and has been given uttermost care by stake holders. The goal of the article is to determine if India is ready to meet Sustainable Development Goal No. 5 of the UN by critically examining its position in relation to other nations. The paper builds argument on the basis of secondary sources as study of current literature published in journal, books, reports of different, NGOs, Government and international organizations and websites. The study critically looks at several approaches and aspects of women’s empowerment in India. Indicators of women’s empowerment, government policies and programs, and constitutional safeguards are all included in this article. Still, the nation comes in last when compared to other nations. Programs must be reevaluated and altered in order to meet SDG-5 by 2030.
Role of Malnad Areca Marketing Cooperative Society Limited [Mamcos] on The Development of Areca Nut Entrepreneurs: With Special Reference To Shimoga District
Authors: Raghavendra Prasad N , Savitha V
Published: January 2025

Areca nut (areca catechu. L) commonly referred to as betel nut or supari is the most significant commercial plantation crop. India is a traditional areca growing country in the world and it finds place in all religious, social and cultural occasions in the country. Karnataka remains the largest producer of areca nut, followed by Kerala and Assam. In Karnataka, Shimoga district leads the way in both area and production. The present study considers one of the areca nut marketing cooperative societies called MAMCOS Limited, Shimoga to study the role in marketing of areca nut and to examine the facilities offered for the development of areca nut entrepreneurs. The study employs both primary and secondary data. The primary data has been collected from 120 respondents and secondary data is collected from society’s website and yearly publications. The study finds that the society is providing systematic marketing facility for the sale of areca nut and other facilities such as storage facilities, harvest loan, and advance payment on the produce to carry out processing activities. The study discovers that the MAMCOS Limited is a vital organization for empowering areca nut entrepreneurs by providing various financial and marketing support services to promote local and national development of the economy.