bluuebunny/crossref_metadata_2025 huggingface dataset:
Thyroid dysfunction and its impact on semen quality
Authors: Khanam Deeba , Anjum Shaheen
Published: February 2025

Male infertility is arising as a major problem in past few years. Decline in semen quality is one of the main reasons. Hormones play important role in regulation of male reproductive function by influencing spermatogenesis, and in that context Thyroid hormones have apivotal role to play.Thus, in present study effect of thyroid abnormalities on semen quality was explored.

To evaluate the effect of Thyroid dysfunction on male fertility.

Hundred Semen samples from the males of infertile couple attending the infertility clinic JNMCH AMU were collected in the year 2020-2022 for detailed Semen analysis after proper consent. Simultaneously thyroid status was evaluated in the study group. The effect of Thyroid dysfunction on semen parameters was assessed using appropriate tests for both Quantitative and Qualitative variables.

There was significant reduction in Total sperm Concentration, sperm motility and semen volume in subset of population with Hypothyroidism, however effect of Hyperthyroidism on sperm parameters was adverse but non-significant.
Comparison of manual vaginal morcellation with laparoscopic power morcellation in specimen retrieval during laparoscopic myomectomy
Authors: Nambiar Muralikrishnan , Suresh Y Anupama , Surendran Jithin , Sreenivas Athulya , Bhat Shreevidya
Published: February 2025

Most popular specimen retrieval techniques in laparoscopic myomectomy are manual vaginal morcellation and power morcellation.

This prospective study was conducted from October 2018 to September 2022 and included 150 patients who underwent laparoscopic myomectomy.

: Specimen extraction time was about 9.744 ±1.076 minutes in the vaginal morcellation group and 77.366 ±324.067 minutes in power morcellation group (p value 0.062). Cost of surgery in US dollars was 954.550± 2.272 USD in vaginal morcellation group and 1266.329± 215.246 USD in power morcellation group (p value < 0.001). About 0.013± 0.112 patients in vaginal morcellation group required of additional analgesia post operatively. This was required in about 0.171 ± 0.379 patients in power morcellation group (p value < 0.001). Patients who had vaginal morcellation were discharge ready at 128.625 ± 13.664 minutes. Where as this was 182.561± 30.381 minutes in power morcellation group (p value of < 0.001). About 0.013± 0.112 patients in the vaginal morcelaltion group had wound related adverse effects. About 0.171 ± 0.379 patients had such adverse effects in the power morcellation group (p value < 0.001).

: From our findings we conclude that Manual vaginal morcellartion is a much quicker, inexpensive and less painful alternative to power moecellation to extract specimens after laparoscoic myometomy. Manual vaginal morcellation also has less wound related complications with quicker post operative discharge readiness.
Saúde Coletiva e branquitude: uma revisão de literatura integrativa
Authors: Loureiro Ferreira de Carvalho Polyana , Francisco Lima da Silva Diego , Castelo Branco Correia Lins Aryadne
Published: February 2025

Introduction: This article presents as a research question: “What has been discussed within the literature in the field of Collective Health about the social construction of Whiteness and its impacts from racism?”. Objective: To discuss, based on a literature review, the concept of Whiteness in Public Health studies. Methodology: This is an integrative literature review, focusing to the academic production of Collective Health linked to studies on Whiteness. For the research, the descriptors were chosen by consulting the Descriptors in Health Sciences - DeCS of the Virtual Health Library - VHL platform of BIREME. The search was conducted place in September 2022, through the Scientific Electronic Library Online - Scielo digital library. The analysis of the study was based on Content Analysis, which foresees the classification of the analyzed results in different or similar categories, through a set of techniques applied in the field of communications. Results: The search found 53 journals. Based on the inclusion and exclusion criteria, an analysis of the titles, abstracts and reading was carried out, where 08 articles were identified that discussing the pre-established themes. Discussion: The construction of a racial consciousness is crucial to recognize the structures of power and the social construction of our country, which is crossed by racism in its formation. Whiteness is perpetuated through institutions, cultural norms and social practices, it is not a static concept, but it highlights the privileges to which a segment of the population has access.
HOW DOES INCOME INEQUALITY AFFECT ACADEMIC SUCCESS ACROSS COUNTRIES?
Authors: Çankaya İbrahim
Published: February 2025

The aim of the study is to compare whether there is a significant difference between the PISA exam averages of countries with the highest income inequality and countries with the lowest income inequality and to determine whether there is a significant relationship between income inequality and PISA success. The study group was selected from among the countries with the highest and lowest income inequality according to the GINI index using the contrast sampling technique, which is a purposive sampling technique. T-test, correlation and simple linear regression analyses were conducted on income inequality and PISA scores. The average PISA scores of the 12 countries with the highest income inequality and the 12 countries with the lowest income inequality were compared with the average scores of the same countries regarding income inequality. There is a significant difference between the average PISA scores of the countries with the highest and lowest income inequality. There is a significant and inverse relationship between income inequality and PISA success. While income inequality increases, PISA success decreases, while PISA success increases as income inequality decreases. According to the simple linear regression model, income inequality predicts PISA success significantly as the only independent variable. Income inequality is a determinant of students' academic success.
Advancing AI in Edge Computing with Graph Neural Networks for Predictive Analytics
Authors: Manduva Vinay Chowdary
Published: February 2025

The rise of edge computing has transformed the ways in which the data is consumed, analyzed and utilized with the possibilities of decision making at the point when they come into the creation. However, the traditional machine learning approaches are not suitable in the modern smart applications like smart cities, health care, and IoT due to the dynamic, distributed and resource limited nature of the edges. As a result, existing machine learning techniques fall short of handling these issues, and Graph Neural Networks (GNNs), are the solution to these challenges due to their ability to model and learn from graph-structured data.
The present article offers a detailed examination of how GNNs can be incorporated into edge computing to enhance the development of prediction techniques. It describes the architecture of GNNs and focuses on the benefits offered by these networks in learning and analyzing connected data and deeply embedded patterns that escape other architectures. We expand the discussion on factors influencing GNNs deployment on edge devices to include computational capabilities, latency, and security threats. To solve these problems, several solutions are put forward including the model optimization, lightweight algorithms, and federated learning.
Moreover, to validate the novelty of edges-GNN integration and its capabilities, real-world cases are also discussed. Applications are, for example, in intelligent transportation systems in smart cities, in force IoT and in diagnostics in medicine. However, the integration of GNNs and edge computing is a way of opening up more opportunities for the development of efficient, scalable and privacy preserving analytic prediction systems.
Finally, the authors present the outlook for further research, in which they consider the potential application of self-supervised learning, the interaction with new technologies like quantum computing or the creation of collaborative platforms for the definition of a clear edge AI system. This work also established the significance a of narrowing the divide between advanced AI techniques and edge computing in opening the possibility for revolutionary advancements in predictive analytics across fields.
¿Qué Hacemos Con Los Juicios Paralelos?
Authors: Lascuraín Sánchez Juan Antonio
Published: February 2025

Los juicios paralelos no son ejercicio de justicia popular, pero sí manifestación de la esencial libertad de expresión en asuntos de interés público. El problema es que no son paralelos, sino oblicuos, porque inciden en la también sagrada presunción de inocencia: pueden pervertir la presunción, la prueba y la imparcialidad judicial. Para solucionar este conflicto de valores constitucionales se han propuesto malas y buenas estrategias. Entre las primeras está la penalización de los juicios paralelos, el aplazamiento del juicio, la absolución y la recusación del juez. Mejor camino es el que marcan los deberes penales de secreto de funcionarios y partes procesales, la prohibición de entrevistas a testigos, la atenuación de la pena en casos extremos y la supresión total o parcial del jurado.
Effect of Mustard-based Intercropping Systems on Efficiency Indices under Organic Management
Authors: Singh Umesh Kumar , Gangwar B. , Kumar Sourabh , Kumar Rajiv
Published: February 2025

Background: Intercropping has potential to increase land productivity by leveraging species complementarities and a means to achieve sustainable agricultural intensification. The mustard intercropping with other crops significantly modified the competition parameters when compared to their comparable sole crops. Methods: An experiment was carried out at Organic Research Farm, Karguaji, Institute of Agricultural Sciences, Bundelkhand University, Jhansi, during Rabi 2021-22 to investigate the effect of mustard-based intercropping systems utilizing the skip-row method on efficiency indices under organic management. Nine treatments were investigated, including mustard, kabuli chickpea, field pea, fenugreek and desi chickpea as sole crops, mustard + kabuli chickpea, mustard + field pea, mustard + fenugreek and mustard + desi chickpea (1:2 ratio) in an intercropping system omitting one row of mustard. Result: Intercropping of mustard with desi chickpea showed positive trends in terms of efficiency indices with higher CGR (17.8 g.day-1cm-2), RGR (17.90 g.g-1.day-1), LER (1.64), MEY (26.7qha-1), CEY (25.87 qha-1) and ATER (1.64) which ultimately resulted in highest profitability (Rs 888 ha-1 day1).
AMMI Biplot Analysis of Genotype ´ Environment Interactions in Rainfed Grown Green Gram [Vigna radiata (L.) Wilczek]
Authors: Naresh Thotla , Verma Sanjay Kumar , Panwar Ravindra Kumar , Reddy S.G.P. Karthikeya , Rana Anupriya , Bhatt Ashish , Mehra Ayushi , Pragati Kumari
Published: February 2025

Background: Mungbean [Vigna radiata (L.) Wilczek] commonly called green gram, holds significant importance as a pulse crop in India and contribute significantly towards the national food security. Pulses present an option for diversifying agricultural systems; however, their low and varying yield under different environmental conditions makes them less competitive compared to cereals, oilseeds, and cash crops. Therefore, it is essential to screen and identify stable genotypes those can perform consistently well across various agro climatic conditions. Methods: The G´E interaction for yield and its component characters in mungbean were analyzed by using the AMMI (additive main effects and multiplicative interaction) model. The data was collected on 40 elite mungbean genotypes which were grown in four rainfed environments. Result: The study found highly significant effects (P less than 0.01) of genotype (G), environment (E) and G´E interaction (GEI) for all 10 characters analyzed. Gollob’s test showed IPCA I was significant for all traits; IPCA II was significant for all except days to maturity and pod length; IPCA III was significant for plant height, primary branches per plant, number of clusters per plant, number of pods per cluster, total pods per plant, and seed yield per plant. Over 69% of GEI sum of squares were explained by IPCA I. Significant GEI supports AMMI analysis for identifying stable genotypes, with AMMI residual SS non-significant for most traits, indicating model accuracy. Genotypes IPM 02-3 (G9), PM 15-20 (G37) and PM 15-7 (G24) showed low interaction for seed yield per plant. This AMMI model analysis of mungbean yield under rainfed conditions provides valuable insights for breeding drought-tolerant mungbean varieties.
Optimización de la asignación de docentes en la gestión de una asignatura: lecciones de un caso en estudios de pregrado.
Authors: Fernández Bringas Alberto Moisés Ramón , Clark Leza Daniel , Vidal Bonilla Marcela
Published: February 2025

El ensayo explora la importancia de optimizar la gestión de las asignaturas de una carrera de pregrado tomando en cuenta las actividades que se realizan, la disponibilidad de recursos y teniendo como objetivo maximizar el logro de los resultados de aprendizaje que conducen a las competencias del perfil de egreso. Se estudia el caso de una asignatura de cuatro créditos y con horas teóricas y horas prácticas entre los años 2019-2023; se describen los cambios en la repartición de las responsabilidades en el equipo docente y se comparan los indicadores de desempeño de cumplimiento y de satisfacción con la docencia en dos periodos distintos.
Asimismo, se validan los resultados empleando un modelo de programación lineal para evaluar si la asignación de recursos es la óptima. La comparación entre periodos muestra que cuando el equipo docente integra al coordinador del curso (o docente principal) con un jefe de práctica (en un trabajo paralelo), se obtienen mejores resultados que cuando el coordinador del curso es el único encargado de desarrollar la totalidad de actividades en un trabajo secuencial. Esto probablemente se deba a que el coordinador libera recursos para un mejor seguimiento de la asignatura, mientras que el jefe de práctica se dedica al manejo y calificación de las prácticas semanales. Los resultados sugieren que adoptar una docencia de trabajo paralelo entre la coordinación, la docencia teórica y la práctica, así como planificar según la naturaleza de cada asignatura, va a contribuir a una mejor ponderación de recursos que optimice los resultados de aprendizaje.
Pain Type and Quality of Life in Cervicogenic Headache Patients
Authors: Sudibyo Devi Ariani , Fathoni M Reza , Puti Nazla Ananda Rachmi
Published: February 2025

Highlight:

Cervicogenic headache is the most incapacitating type, leading to significant physical impairment.
Based on the data, there were 15 subjects in the nociceptive pain group and 15 subjects in the neuropathic pain group.
There was a statistically significant correlation between the type of pain and the mental quality of life. In patients with cervicogenic headaches and neuropathic pain, there was a stronger relationship than those with nociceptive pain.

 
ABSTRACT
Introduction: Cervicogenic headache is classified as a secondary headache under the International Classification of Headache Disorders, third edition (ICHD-3). Significant neuropathic and nociceptive pain components are believed to be present in this condition, which eventually lowers quality of life by causing problems like anxiety, depression, and sleep disruptions. Objective: This study aimed to correlate pain types with quality of life in those suffering from cervicogenic headaches. Methods: A cross-sectional observational study was conducted at the Neurology Outpatient Clinic of Dr. Soetomo General Academic Hospital in Surabaya from June to August 2020. Quality of life and pain types were evaluated using the painDETECT and SF-36 questionnaires. A painDETECT score of 12 or less indicated nociceptive pain, but a score of more than 12 indicated neuropathic pain. An SF-36 score below 50 indicated a poor quality of life. Conclusion:Patients with cervicogenic headaches and neuropathic pain exhibited a lower quality of life compared to those experiencing nociceptive pain. These findings emphasize the importance of evaluating pain types to support the maintenance of a good quality of life.
Neuroimaging and Intravenous Recombinant Tissue Plasminogen Activator in Acute Ischemic Stroke beyond 4.5 Hours: A Systematic Review
Authors: Ghifari Muhammad Ramadhan , Deskianditya Resa Budi , Oviyanti Pradana Nur , Maatisya Yuki Fitria , Putri Vega Pratiwi
Published: February 2025

Highlight:

Ischemic stroke is a major cause of disability and death globally, emphasizing the urgent need for timely and effective thrombolytic interventions within a narrow treatment window.
Neuroimaging has the potential to extend the therapeutic window for IV rt-PA beyond 4.5 hours, allowing clinicians to identify patients with salvageable brain tissue for treatment.
Extending the IV rt-PA treatment window with neuroimaging support can significantly improve outcomes in stroke patients, although careful risk assessment is crucial.

 
ABSTRACT
Introduction: Current guidelines suggest giving intravenous recombinant tissue plasminogen activator (rt-PA) within 4.5 hours after acute ischemic stroke onset or the time the patient was last-seen-well. Patients often arrive at the hospital after 4.5 hours, making thrombolysis treatment challenging. It is crucial to examine expanding this timeframe beyond 4.5 hours of onset or last-seen-well. Objective: This systematic review intended to examine the effectiveness and safety of IV rt-PA in patients presenting to the hospital beyond 4.5 hours of onset or last-seen-well. Methods: We searched PubMed, Scopus, and ScienceDirect for studies on acute ischemic stroke patients treated with IV rt-PA alteplase beyond 4.5 hours of onset or last-seen-well. Outcomes comprised the Modified Rankin Scale (mRS) score, intracranial hemorrhage (ICH), symptomatic ICH, and mortality. We assessed the risk of bias using Cochrane Risk of Bias Vol 2 and ROBINS-I. Results: Eleven randomized controlled trials and observational studies were selected. Most subjects were above 65 years, and their baseline mean or median NIHSS scores were 6–12. Seven studies had specific neuroimaging criteria for eligibility, such as DWI/FLAIR or T2WI mismatch, PWI/DWI mismatch, or CT/MR perfusion. In RCTs, alteplase group had 47.1% to 53.3% favourable results (mRS 0-1) compared to 41.3% to 48.3% in placebo/controls group and 23% to 85% in observational studies. Compared to the placebp/control group and onset within 4.5 hours, alteplase typically had better ourcomes. However, ICH, symptomatic ICH, and mortality were numerically higher, albeit not statistically significant. Conclusion: IV rt-PA alteplase can be given  for up to 9-12 hours from onset or last-seen-well with neuroimaging evidence of salvageable tissue, such as the perfusion imaging RAPID criteria or DWI/FLAIR or T2WI mismatch, taking consideration of hemorrhage and mortality concerns.
Epidemiological Study of Stroke Disease in the Southeast Maluku Islands Region in 2023
Authors: Paliyama Febryn Prisiliya , Rinaldi Fransiskus Xaverius , Silalahi Parningotan Yosi , Nari Janti Pare
Published: February 2025

Highlight:

The prevalence of stroke in Southeast Maluku is 14.1 per 1,000 population for 2023.
Ischemic stroke is the most common type of stroke in the Southeast Maluku Islands.
The most prevalent chronic disease among stroke patients in Southeast Maluku Islands is hypertension.

 
ABSTRACT
Introduction: Stroke is a serious health problem with a high mortality rate and incidence, especially in low- and middle-income regions like Southeast Maluku, Indonesia. Inadequate facilities and risk factors causing high stroke rates in this region provide major healthcare challenges. Epidemiological data highlight the pressing need for healthcare development.  Objective: This epidemiological study aimed to provide insight on the prevalence of stroke in the Southeast Maluku Islands in 2023, with the goal of enhancing the urgency of measures to reduce stroke incidences there. Methods: This study used a descriptive methodology with a cross-sectional design. Data were collected by obtaining thorough medical records from stroke patients at Karel Sadsuitubun Regional General Hospital. Demographic information, stroke type, and comorbidities were analyzed, as well as the prevalence rate calculated from the entire patient population of 8,436 as reported in 2023, while also classifying patients by age and gender. Results: In the Southeast Maluku Islands, 107 stroke cases were reported, equal to a stroke prevalence rate of 12.6 per 1,000 people. The most common type was ischemic stroke (95.33%), followed by hemorrhagic stroke (4.67%). Hypertension, which affected 67.2% of patients, was the most common comorbidity, followed by type II diabetes mellitus and coronary artery disease. Conclusion:Stroke rates have increased in the Southeast Maluku Islands due to a variety of factors, including socioeconomic conditions and unhealthy lifestyles. The study’s findings emphasize the urgent need for interventions to reduce stroke rates.
Epidemiologic Profile of Ischemic Stroke Patients with Dyslipidemia in Dr. Soetomo General Academic Hospital Patient
Authors: Prakoso Raditya Ardra Putra , Ardhi Mohammad Saiful , Thamrin Husin , Setyowatie Sita
Published: February 2025

Highlight:

This study provides insights into the epidemiologic profile of ischemic stroke patients with dyslipidemia in Dr. Soetomo General Academic Hospital.
The majority of patients had hypertension, the most common comorbidity with low HDL-C levels
Most patients showed moderate stroke severity and high levels of consciousness, with a majority proportion demonstrating recovery.

 
ABSTRACT
Introduction: Ischemic stroke is a major medical issue, especially in individuals with dyslipidemia, as it can elevate both the likelihood and severity of stroke incidents. This study is essential due to the rising prevalence of stroke and limited data regarding ischemic stroke patients with dyslipidemia in Indonesia. Understanding these traits is important for enhancing preventative and treatment strategies. Objective: This study intended to assess the epidemiologic profile of ischemic stroke patients with dyslipidemia in a tertiary hospital in Indonesia. Methods: This descriptive study assessed 116 medical records of ischemic stroke patients with dyslipidemia admitted to Dr. Soetomo General Academic Hospital in Surabaya, Indonesia, from January to June 2023. The collected data encompassed demographics, comorbidities, lipid profiles, and clinical outcomes. Dyslipidemia was defined based on the PERKENI guidelines, and stroke severity was assessed using the GCS and NIHSS scales. Results: The majority of ischemic stroke patients with dyslipidemia (77.6%) had low HDL-C levels. There were 64 males and 52 females; most of them were between the ages of 56 and 65. Hypertension was the most common comorbidity (64.7%), followed by diabetes (39.7%), heart disease (12.9%), and obesity (11.2%). Of 40 NIHSS-assessed patients, 26 had moderate, 8 mild, 2 moderate-to-severe, and 4 severe strokes. The majority of patients (70.7%) recovered. Conclusion:The majority of dyslipidemia-related ischemic stroke patients, aged 56 to 65, had low HDL-C levels. Hypertension was the main comorbidity, with many experiencing their first stroke. Most patients had high consciousness, moderate stroke severity, and showed improvements.
Efficacy of Hyperbaric Oxygen Therapy in Systemic Lupus Erythematosus Patients Undergoing Maxillofacial Surgery
Authors: Eko Mukti Wibowo  , Ganendra Anugraha  , Agung Satria Wardhana
Published: February 2025

Highlights

SLE is the most common autoimmune disease that requires management after maxillofacial surgery.
Hyperbaric oxygen therapy is a treatment that can help accelerate recovery in patients.

 
Abstract
Background:  Systemic Lupus Erythematosus (SLE) is a common multifactorial autoimmune disease that carries a high risk of osteoporosis and fractures. The delivery of oxygen to the body's tissues through hyperbaric oxygen treatment (HBOT) promotes the healing of wounds and shortens the typical recovery time for patients. The way tissues react to illnesses and injuries can be altered by HBOT. Objective: This article aimed to determine the use of hyperbaric oxygen therapy (HBOT) post-maxillofacial surgery in SLE patients. Materials and Method: This research used a scoping review approach, accessing electronic databases like PubMed, Scopus, Science Direct, Elsevier, and Google Scholar. Discussion: SLE is characterized by producing various autoantibodies that interact with endogenous antigens, favoring widespread inflammatory injury. SLE impacts the immune system, diminishing its ability to defend against infections. Hyperbaric oxygen therapy refers to administering 100% oxygen to a patient inside a pressurized chamber with a pressure higher than one atmosphere at sea level. The surgical placement of the implant into the mandible or maxilla allows it to be retained during functional loading, as the bone integrates with the implant during growth. Conclusion: HBOT can improve the host response by activating inflammatory cells and ensuring optimal oxygen tension in people with SLE. This can help with osteogenesis and neovascularization, which fill empty spaces with new blood vessels or bone tissue.
Gut-Brain Axis, Notch, and Brain Cancer: ‘The Rising Three’
Authors: Gembong Satria Mahardhika  , Norina Agatri
Published: February 2025

Highlights

The gut-brain axis (GBA) is a bidirectional communication network linking the gastrointestinal tract and the central nervous system (CNS), involving neurons and various signaling molecules such as endocrine, humoral, metabolic, and immunological factors.
The Notch signaling pathway is implicated in the development of brain tumors, including gliomas, which show elevated Notch receptor levels. This pathway is critical in tumor cell proliferation, survival, and invasiveness.

 
Abstract
Background: The gut-brain axis (GBA) facilitates reciprocal communication between the central and enteric nervous systems. The connection between the GBA, Notch, and brain cancer is a complex and intricate subject that warrants further exploration. Brain cancer has a multifaceted pathophysiology and structure, making the journey from diagnosis to treatment challenging. The involvement of Notch in the signaling pathway could be relevant to both brain cancer and the gut-brain axis. Objective: This research aimed to examine the complex interplay between the gut-brain axis (GBA), Notch signaling, and brain cancer, specifically gliomas. Material and Method: This study was a scoping review conducted using multiple search engines, including PubMed, ProQuest, and Cambridge Core, spanning from 2018 to 2023. The collected materials were filtered and subsequently analyzed. Result: The existence of the gut-brain axis is a fascinating topic for in-depth exploration. The complex relationship between Notch and the gut-brain axis may offer valuable insights into the pathogenesis of brain cancer. The literature review identified two publications, which were analyzed in more detail. The gut-brain axis (GBA) refers to a bidirectional communication network between the central nervous system and the enteric nervous system, regulating gastrointestinal functions. The identification of the Notch signaling pathway suggests its role in the development of brain tumors. Conclusion: The connections between the gut-brain axis, Notch, and brain cancer are evident. The Notch pathway, as a signaling mechanism, is linked to brain cancer, and the gut-brain axis is also associated with it. This interconnected relationship has the potential to uncover novel avenues for diagnosis and therapy, warranting further research.
IRON INTAKE AND STRESS LEVEL WITH PRIMARY DYSMENORRHEA IN HIGH SCHOOL STUDENTS
Authors: Muawanah Nur , Kurniawati Meti , Alamsyah Putri Rahmah , Widhi Anisa Sekar
Published: February 2025

One of the signs of puberty experienced by young women is menstruation, some young women experience pain known as dysmenorrhea during menstruation. Iron is one of the essential nutrients for adolescent reproduction, and its deficiency can increase the risk of dysmenorrhea. Stress can also affect Dysmenorrhea, as stress can lead to hormonal imbalances and the secretion of prostaglandin hormones produced by stress. The purpose of this study was to analyze the relationship between iron intake and stress levels with the incidence of primary dysmenorrhea in adolescent girls at PB Soedirman Islamic High School Bekasi. This study uses an observational analytic method with a cross-sectional design, and data collection using consecutive sampling techniques with 100 respondents. Data were collected through semi-quantitative food frequency questionnaires (SQ-FFQ) and Perceived Stress Scale (PSS) and determining the incidence of dysmenorrhea using dysmenorrhea questionnaires. The results measured by Chi-square test, showed p-values for iron intake (0.010) and stress levels (0.002). This study found a significant correlation between stress levels and iron intake in adolescent girls in PB Soedirman Islamic High School Bekasi.
Determinant of Household Food Waste: A Direct Measurement Study in Tanah Sareal Sub-District of Bogor City
Authors: Rahmaniya Liya Putri , Briawan Dodik , Sukandar Dadang , Swamilaksita Prita Dhyani
Published: February 2025

The percentage of food waste generation has increased in Indonesia for 20 years, with 80% of food waste coming from households. This can cause various significant negative impacts on the environment, economy and social. Various factors affect the production of household food waste. This study aims to analyze household food waste based on its quantity, type, and determinants. This study uses some secondary data from primary research conducted by Swamilaksita (2024) with a cross-sectional design. The study sample of 110 households was selected using a stratified random sampling technique. Food waste data was obtained through direct measurement using the SNI 19-3964-1994 method. The entire data was analyzed descriptively, while multiple linear regression analysis was carried out to determine the determinants of household food waste. This study showed that the average amount of food waste was 318.4 g/HH/day and 76.7 g/cap/day. The cereal group was the most discarded food group, followed by vegetables and fruits group. Only three variables were proven to be statistically significant (p-value<0.1) affect the average amount of household food waste, namely the number of household members (p=0.000), mother work as civil servant/private employee (p=0.049), and purchasing and spending behavior (p=0.084). The conclusion was there is an average amount of food waste in units per household and per capita, with the dominant food group is the cereal group, as well as the determinants of household food waste, including number of household members, mother work as a civil servant/private employee, and purchasing and spending behavior.
Mechanoimmunomodulation-based strategy on advancing tissue-engineered nanotopographic structures
Authors: Ao Yong , Xia Ruidi , Guo Yuanlong , Cai Yihua , Guo Xinyu , Wang Jingyi , Chen Zetao
Published: February 2025

The application of nanotopographic structures is considered a promising strategy for improving outcomes in tissue engineering. Nanotopographic structures-mediated immune responses have a more profound influence than the direct modulation of functional cell responses. However, the reported immunomodulatory effects of different nanotopographic structures are inconsistent and unpredictable. Therefore, it is necessary to further understand the general or fundamental biological mechanisms underlying nanotopographic structures-mediated immune regulation to fabricate structures with the desired immunomodulatory properties. Compared to the effects on protein absorption and physiochemical signals, the mechanical forces induced by nanotopographic structures play a more pivotal role in determining immune responses. Elucidating the mechanotransduction mechanisms by which mechanical forces from nanotopographic structures are converted into intracellular biochemical signals in immune cells is crucial. This understanding is essential for the precise regulation of immune responses mediated by nanotopographic structures and for guiding the development of nanotopographic structures with advanced immunomodulatory properties. This review elucidates the impact of nanotopographic structures on cellular mechanical forces and the subsequent activation of mechanosensors. The ensuing mechano-regulatory effects on immune responses are reviewed, and mechanoimmunomodulation is proposed as a strategy for designing nanotopographic structures to modulate immunity. This review contributes to revolutionizing the strategy for developing nanotopographic structures and promotes the application of nanotopographic structures with the mechanoimmunomodulatory property in tissue engineering.
Strategi Pemasaran Kerupuk Udang di Desa Tanjung Dewa Kecamatan Panyipatan Kabupaten Tanah Laut (Studi Kasus pada Usaha Kerupuk Udang Merek Nyai Kasnah)
Authors: Septiana Dwi , Fauzi Muhammad , Azis Yusuf
Published: February 2025

Kerupuk udang merek Nyai Kasnah merupakan usaha perorangan yang dimiliki oleh ibu Kasnah yang beroperasi sejak 2011 hingga sekarang. Keberadaan strategi pemasaran didasarkan pada analisis menyeluruh terhadap dampak faktor lingkungan eksternal dan internal perusahaan. Lingkungan eksternal perusahaan berubah dengan cepat setiap saat, menciptakan berbagai peluang dan risiko baik dari pesaing utamanya maupun lingkungan bisnis yang selalu berubah. Penelitian ini dilaksanakan pada pada bulan Juli 2023 hingga oktober 2023 usaha pengolahan kerupuk udang “Nyai Kasnah” produksi Nyai Kasnah  yang terletak di desa Tanjung Dewa Kecamatan Panyipatan, Kabupaten Tanah Laut. Metode yang digunakan dalam penelitian ini adalah metode studi kasus. Berdasarkan  Identifikasi faktor internal yang mendapatkan hasil enam faktor kekuatan dan lima faktor kelemahan yang dimiliki usaha Kerupuk Udang Nyai Kasnah. Sedangkan faktor eksternal mendapatkan hasil lima faktor peluang dan empat faktor ancaman. Strategi yang dimiliki kerupuk udang Nyai Kasnah berada di kuadran I yang berarti menguntungkan. Nyai Kasnah dapat memanfaatkan kekuatan yang dimiliki sebagai peluang usaha.
Analisis Pengendalian Persediaan Bahan Baku Kerupuk Bawang “Mr” di Kecamatan Cempaka Kota Banjarbaru
Authors: Raihanah Raihanah , Yulianti Mira , Budiwati Nina
Published: February 2025

Penelitian ini bertujuan untuk menganalisis pengendalian persediaan yang diterapkan pada usaha kerupuk bawang “MR” dan untuk menganalisis jumlah pesanan persediaan yang ekonomis pada usaha kerupuk bawang “MR” di Kecamatan Cempaka Kota Banjarbaru. Penelitian ini dilaksanakan pada tahun 2023. Penelitian ini menggunakan metode studi kasus. Jenis data yang digunakan yaitu data primer dan sekunder. Berdasarkan hasil penelitin, frekuensi pemesanan usaha kerupuk bawang “MR” yaitu 10 kali pada periode tahun 2022, dengan 1 kali pemesanan setiap bulan, biaya pemesanan Rp3.673.000,00 untuk 713 kg kerupuk bawang dan  Rp1.514.840,00 untuk biaya penyimpanan, jadi totalnya mencapai Rp5.187.000,00. Usaha kerupuk bawang “MR” tidak memiliki Sefety Stock (Persediaan Pengaman jadi usaha ini  pernah mengalami kekurangan bahkan kehabisan bahan baku. Dengan menggunakan metode EOQ (Economic Order Quantity), didapat jumlah pesanan ekonomis dengan frekuensi pemesanan 2 kali dalam setahun dengan jumlah pemebelian 496 kg kerupuk bawang, usaha kerupuk bawang “MR” dapat membayar biaya pemesanan ekonomis sebesar Rp527.944,00 per pesan dan biaya penyimpanan sebesar Rp527.000,00 Safety Stock (Persediaan Pengaman) sebanyak 48 kg untuk menghindari kekurangan persediaan kerupuk bawang. Jika kerupuk bawang mencapai  sebanyak 16,2 kg, ROP dilakukan. Waktu tunggu adalah sekitar 6 hari.
Analisis Usaha Wisata Petik Buah Kiram Farm di Kabupaten Banjar
Authors: Pujiani Ribka Dhea , Muzdalifah Muzdalifah , Ferrianta Yudi
Published: February 2025

Wisata Petik Buah Kiram Farm adalah bentuk usaha yang mengembangkan serta memanfaatkan potensi pertanian dan alam dengan cara memetik buah langsung dari kebunnya sebagai daya tarik wisata. Tujuan dari penelitian ini yaitu untuk mendeskripsikan usaha Wisata Petik Buah Kiram Farm serta menganalisis biaya, penerimaan dan keuntungan usaha Wisata Petik Buah Kiram Farm. Penelitian ini dilakukan dengan metode studi kasus, menggunakan data yang diperoleh dari sumber data primer dan sekunder. Berdasarkan hasil penelitian, Wisata Petik Buah Kiram Farm menawarkan pengalaman bagi pengunjung dengan menyediakan berbagai jenis buah yang dapat dipetik langsung dari kebunnya. Adapun produk yang ditawarkan selama periode penelitian yaitu berupa buah jambu kristal, belimbing, lemon dan pepaya california. Usaha ini memiliki potensi pengembangan yang besar karena berada di lokasi yang strategis dengan pesona keindahan alam serta mudahnya akses bagi pengunjung dari luar daerah. Namun, terdapat permasalah yang dihadapi, seperti perubahan cuaca yang tidak terduga yang menyebabkan ketidakpastian dalam jumlah buah yang dapat dipetik. Selain itu, kurangnya promosi yang dilakukan juga menyebabkan sedikit pengunjung, dan berpengaruh terhadap pendapatan usaha. Total biaya yang dikeluarkan usaha ini selama periode penelitian yaitu sebesar Rp 56.841.625, dengan biaya tetap sebesar Rp 17.499.625 dan biaya variabel sebesar Rp 39.342.000. Total penerimaan sebesar Rp 81.336.000 dan keuntungan yang diperoleh sebesar Rp 24.494.375, dengan rata-rata sebesar Rp 8.164.792/bulan.
Key Audit Matters and their Impact on the Financial Statements of Listed Entities
Authors:   Vasile Alecsandri University of Bacau, Romania, BOTEZ Daniel , STANGACIU Oana Ancuta ,   Vasile Alecsandri University of Bacau, Romania, MELEGA Anatol ,   Stefan cel Mare University of Suceava, Romania, ENACHI Mihaela ,   Vasile Alecsandri University of Bacau, Romania
Published: February 2025

This research examines how the implementation of
International Auditing Standard 701 – Communicating Key
Audit Matters in the Independent Auditor’s Report (ISA
701), introduced by the International Auditing and
Assurance Standards Board (IAASB) in 2015 and
mandatory since December 2016, affects the
transparency and integrity of financial reports of
companies listed on the Bucharest Stock Exchange
(BSE). ISA 701 encourages more effective communication
of key audit matters, emphasizing their importance in
strengthening the quality of statutory audit. This study
focuses on how these key matters are identified and
communicated in the audit reports and on their impact on
investor behavior and management decisions. The paper
had as starting point 83 entities listed on the Bucharest
Stock Exchange, and following the application of strict
criteria, in order to ensure the relevance and comparability
of information, the sample was reduced to 40 entities for
which the trends in presentation of key audit matters
between 2020 and 2022 were analyzed. The results
suggest a significant link between the clarity and breadth
of communication of these matters and strategic
management decisions, which are directly reflected in the
financial evolution of companies. This analysis contributes
to the literature by highlighting the role of effective
communication of key audit matters in promoting
transparency and accountability within listed entities,
highlighting the positive potential for investor confidence
and capital market stability.
Navigating Auditing Risks in the Crypto Asset Landscape
Authors:   West University of Timişoara, Romania, LAZEA (TRIFA) Georgiana – Iulia , BUNGET Ovidiu Constantin ,   West University of Timişoara, Romania, BALAN Anca Diana ,   West University of Timişoara, Romania, SOLOVASTRU Mircea Stefan ,   Bucharest Stock Exchange
Published: February 2025

The rise of crypto assets presents unique challenges and
risks for auditors, requiring a revaluation of traditional
auditing practices. This paper explores the inherent,
control, valuation, and related risks associated with crypto
assets, emphasising the complexities of valuation,
compliance, and fraud detection. Starting from a
bibliometric visualisation in VOSviewer, it points out
thematic trends and key concepts in crypto auditing. The
database was downloaded from the Web of Science Core
Collection (2000-2024 Q3). The findings offer valuable
insights for auditors, policymakers, investors, researchers,
and practitioners who rely on accurate audits to make
informed decisions and build trust and transparency in the
crypto ecosystem.
Fraud Research in Economic Entities – A Conceptual Perspective
Authors:   Bucharest University of Economic Studies, Romania, TUNSU Alexandru Adrian
Published: February 2025

In the growing complex and mutualistic context of global
economies, addressing the circumstances in which fraud
is observed is becoming of fundamental importance.
National and global economies are severely affected by
fraud by economic entities through significant financial
losses, diminished investor confidence and the creation of
financial market imbalances. From this perspective, the
research objective is to identify and analyse
multidimensional conceptual approaches to fraud. Using a
bibliometric analysis of articles published in the Scopus
database in the period 1982-2023, the research directions
in the literature, the frequency and relevance of the topics
addressed, the authors and papers with major influence,
as well as the collaboration networks among researchers
were identified. The results of the research highlighted the
continuing interest in addressing fraud but also its multiple
connotations. Considering the economic, governmental
and social implications of fraud, the research is deemed to
add value to the literature and the changing economic
context is a premise for further research on fraud.
Respectful pruning in young vineyards: impact on growth and potential implications
Authors: Galar-Martínez Mónica , Torres Nazareth , Sebastián Bárbara , Palacios Julián , Arzoz Ignacio , Juanena Nahiara , Villa-Llop Ana , Loidi Maite , Dewasme Coralie , Roby Jean-Philippe , Santesteban Luis Gonzaga
Published: February 2025

In recent years, there has been a resurgence of interest in grapevine pruning. This growing focus has emerged as a response to the long-term issues that poor pruning practices have caused in vineyards. Decades of neglecting fundamental principles of pruning, driven by a focus on increasing yields and reducing costs, have probably contributed significantly to vineyard decline. This renewed attention seeks to reverse the damage done by poor practices, emphasising the importance of proper wound management, sap flow preservation, and a more thoughtful approach to vine care - ultimately aiming to enhance vine longevity and health - which is commonly known as “gentle” or “respectful” pruning.
Caractérisation de la dynamique d’accumulation du sucre dans le raisin et des facteurs influençant ce processus à l’échelle locale
Authors: De Rességuier Laure , Inchboard Lauren , Parker Amber K. , Petitjean Théo , Van Leeuwen Cornelis
Published: February 2025

Déterminer la concentration en sucre dans les baies de raisin est essentiel pour les viticulteurs, car elle permet d'évaluer le degré d’alcool du vin final et d'optimiser la date de récolte. Face au changement climatique et à l'augmentation des températures, comprendre les facteurs qui affectent la dynamique d'accumulation du sucre est crucial pour adapter les pratiques viticoles et maintenir la qualité des vins. Cette étude vise à analyser les facteurs de développement et environnementaux impliqués dans l'accumulation du sucre dans les raisins, en utilisant des données collectées dans la région de Saint-Émilion, Pomerol et leurs appellations satellites (Bordeaux, France) (de Rességuier et al., 2024).
QUEM FALA NO DIA DA CONSCIÊNCIA NEGRA?: um estudo das fontes jornalísticas na mídia hegemônica no Maranhão
Authors: Rocha Ariel Santos da , Bueno Thaisa , Sousa Leila
Published: February 2025

A pesquisa aqui proposta faz uma análise das fontes acionadas em matérias que pautam o Dia da Consciência Negra, questões raciais publicadas no dia 20 de novembro ou que pautem a data mesmo em outros dias durante os anos do recorte, com a celebração como gancho. A pesquisa foi feita em dois veículos tradicionais maranhenses: o site de notícias Imirante.com e o antigo jornal impresso O Estado do Maranhão, ambos do Grupo Mirante. Para tanto, o artigo realizou um levantamento das matérias jornalísticas, compondo um universo de quase duas décadas de recorte temporal, que vai de 2002 a 2021. Ao todo são 49 matérias de autoria própria dos veículos que compõem o corpus de aprofundamento da pesquisa, de onde foram coletadas 69 fontes utilizadas nas produções. Entre os resultados encontrados, ressaltamos de antemão a baixa cobertura que comtemple uma produção própria dos jornais, expressada no pequeno volume de matérias autorais encontradas em 19 anos de levantamento. Também constatamos que não são comtempladas a diversidade de fontes e a variedade de enfoques. Também se percebe a falta de aprofundamento nas matérias que pautam a celebração. Poucas vezes as fontes foram utilizadas para fins de enriquecer a produção de forma mais firme e o cidadão comum quase não tem espaço.
A CONSTRUÇÃO DE SIGNIFICADOS PARA A COR PRETA NA PUBLICIDADE
Authors: Malagó Graziella Andreia , Drigo Maria Ogécia
Published: February 2025

Com o objetivo geral de contribuir para a compreensão do processo de construção de significados da cor preta, na publicidade, apresentamos conceitos de midiatização, aspectos do processo de construção social da cor preta, e análise semiótica, na perspectiva peirceana, de uma peça publicitária que compõe uma amostra de interesse, com peças publicitárias do ano de 2021, coletadas nos portais da ADS of the Word e do Clube de Criação. A cor preta, na peça selecionada, gera significados vinculados à sobriedade e à funcionalidade, e ora vinculados ao mal, mesclando assim significados cristalizados no meio social com os significados do preto moderno do design.
MEMÓRIAS DA INSTITUIÇÃO EDUCATIVA A PARTIR DAS NARRATIVAS DO PROJETO POLÍTICO PEDAGÓGICO: reminiscências de outrora
Authors: Santos Jocyleia Santana dos , Andrade da Silva André , Cleizenir Divina dos Santos
Published: February 2025

Este artigo tem por objetivo compreender a implantação da Escola Estadual Frederico José Pedreira Neto em Palmas–TO e como as memórias de outrora são registradas na perspectiva do Projeto Político Pedagógico. O estudo pauta-se no método da História Oral, que focaliza a capacidade da memória humana de rememorar o passado na medida em testemunha o vivido. Adota-se a abordagem qualitativa e o tipo de pesquisa bibliográfica, com a aplicação da técnica de análise de conteúdo para interpretação do objeto desta pesquisa. Com base na literatura consultada e na análise realizada do Projeto Político Pedagógico da escola, os dados ressaltam que o colégio foi criado no contexto da implantação da capital, Palmas e da estruturação do Estado do Tocantins, se constituindo como uma escola pioneira, de vários líderes tocantinenses, ainda que fundamenta suas práticas educacionais em concepções pedagógicas, referenciais teóricos e legais que orientam o processo de ensino e aprendizagem, registradas no documento nortear de suas práticas e projetos pedagógicos, desvelando-se como um relevante documento-monumento da história oral e escrita dessa unidade de ensino.