bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplemental Figure 2 from Transcription Factor KLF5 Binds a Cyclin E1 Polymorphic Intronic Enhancer to Confer Increased Bladder Cancer Risk
Authors: Pattison Jillian M. , Posternak Valeriya , Cole Michael D.
Published: April 2023

S2. KLF5 promotes enhanced activity on the high risk versus low risk allele.
Supplementary Table 1 from Chromosome 6p Amplification in Aqueous Humor Cell-Free DNA Is a Prognostic Biomarker for Retinoblastoma Ocular Survival
Authors: Xu Liya , Polski Ashley , Prabakar Rishvanth K. , Reid Mark W. , Chevez-Barrios Patricia , Jubran Rima , Kim Jonathan W. , Kuhn Peter , Cobrinik David , Hicks James , Berry Jesse L.
Published: April 2023

Supplementary Table 1. Retinoblastoma (RB) patient demographics, clinical outcomes, and RB somatic copy number alterations (SCNAs) at a large RB treatment center.
Figure S2 from Kinase-Dependent and -Independent Roles for PTK6 in Colon Cancer
Authors: Mathur Priya S. , Gierut Jessica J. , Guzman Grace , Xie Hui , Xicola Rosa M. , Llor Xavier , Chastkofsky Michael I. , Perekatt Ansu O. , Tyner Angela L.
Published: April 2023

Supplemental Figure: Differential activation of p38 in breast and colon cancer cell lines
Description of Supplemental Figures from Kinase-Dependent and -Independent Roles for PTK6 in Colon Cancer
Authors: Mathur Priya S. , Gierut Jessica J. , Guzman Grace , Xie Hui , Xicola Rosa M. , Llor Xavier , Chastkofsky Michael I. , Perekatt Ansu O. , Tyner Angela L.
Published: April 2023

Legends and Methods
Supplementary Figure Legends from KLF4 Suppresses Tumor Formation in Genetic and Pharmacological Mouse Models of Colonic Tumorigenesis
Authors: Ghaleb Amr M. , Elkarim Enas A. , Bialkowska Agnieszka B. , Yang Vincent W.
Published: April 2023

Supplementary Figure Legends
Supplementary Figure 1 from Aberrant Myosin 1b Expression Promotes Cell Migration and Lymph Node Metastasis of HNSCC
Authors: Ohmura Gaku , Tsujikawa Takahiro , Yaguchi Tomonori , Kawamura Naoshi , Mikami Shuji , Sugiyama Juri , Nakamura Kenta , Kobayashi Asuka , Iwata Takashi , Nakano Hiroshi , Shimada Taketoshi , Hisa Yasuo , Kawakami Yutaka
Published: April 2023

Myo1b is highly expressed in human HNSCC.
Supplementary methods and figures from Constitutive CHK1 Expression Drives a pSTAT3–CIP2A Circuit that Promotes Glioblastoma Cell Survival and Growth
Authors: Khanna Anchit , Thoms Julie A.I. , Stringer Brett W. , Chung Sylvia A. , Ensbey Kathleen S. , Jue Toni Rose , Jahan Zeenat , Subramanian Shruthi , Anande Govardhan , Shen Han , Unnikrishnan Ashwin , McDonald Kerrie L. , Day Bryan W. , Pimanda John E.
Published: April 2023

Figure S1, related to Figure 1: Expression and correlation of CHK1 and CIP2A in multiple glioma cohorts. Figure S2, related to Figure 1: Overall survival and mRNA expression of PP2A subunits in glioma patients. Figure S3, related to Figure 1: Role of CHK1-CIP2A in Glioma Stem cell lines. Figure S4, related to Figure 3: Effect of CHK1 or CIP2A expression on GBM cells. Figure S5, related to Figure 5: Depletion of CIP2A induces senescence in GBM cells. Figure S6, related to Figure 6: Regulation of CIP2A expression by CHK1 and STAT3.
Figure S2 from CD71+ Population Enriched by HPV-E6 Protein Promotes Cancer Aggressiveness and Radioresistance in Cervical Cancer Cells
Authors: Leung Thomas Ho-Yin , Tang Hermit Wai-Man , Siu Michelle Kwan-Yee , Chan David Wai , Chan Karen Kar-Loen , Cheung Annie Nga-Yin , Ngan Hextan Yuen-Sheung
Published: April 2023

Sequencing analysis was also performed for two predicted off-target genes (SLC25A13 and TECTB) in F99 and J76 cells.
Figure S1 from CD71+ Population Enriched by HPV-E6 Protein Promotes Cancer Aggressiveness and Radioresistance in Cervical Cancer Cells
Authors: Leung Thomas Ho-Yin , Tang Hermit Wai-Man , Siu Michelle Kwan-Yee , Chan David Wai , Chan Karen Kar-Loen , Cheung Annie Nga-Yin , Ngan Hextan Yuen-Sheung
Published: April 2023

The mutations in F99 and J76 were validated by sequencing analysis of the gRNA-targeted region in exon 3 of CD71.
Supplementary Figure 1 from Helicobacter pylori Induces a Novel NF-kB/LIN28A/let-7a/hTERT Axis to Promote Gastric Carcinogenesis
Authors: Shen Li , Zeng Jiping , Ma Lin , Li Shuyan , Chen Chunyan , Jia Jihui , Liang Xiuming
Published: April 2023

Figure S1. IF staining of p65 and hTERT in CagA transfected BGC-823 cells.
Supplementary Data from Dual PI3K/mTOR Inhibition in Colorectal Cancers with APC and PIK3CA Mutations
Authors: Foley Tyler M , Payne Susan N. , Pasch Cheri A. , Yueh Alex E. , Van De Hey Dana R , Korkos Demetra P , Clipson Linda , Maher Molly E , Matkowskyj Kristina A. , Newton Michael A. , Deming Dustin A.
Published: April 2023

S1. AP spheroids were plated and allowed to mature for 48 hours. S2. To address the issue of potentially slower growth of the spheres with the largest initial sizes, a change-point analysis was performed. S3. AP mice were treated with control (A) or BEZ235 (B) for 14 days. S4. AP mice were treated with BEZ235 or control for 14 days. S5. AP spheroids were treated with NVP-BYL719, BEZ235, LY3023414, or control for 24 hours. S5. AP spheroids were treated with NVP-BYL719, BEZ235, LY3023414, or control for 24 hours. Supplementary Table S1. AP spheroids were treated with NVP-BYL719, GDC0941, BEZ235, LY3023414, or control for 48 hours. Supplemental Table S2. AP mice were treated with BEZ235, LY3023414 or control for 14 days.
Figure S6 from Inhibition of the Cell Death Pathway in Nonalcoholic Steatohepatitis (NASH)-Related Hepatocarcinogenesis Is Associated with Histone H4 lysine 16 Deacetylation
Authors: de Conti Aline , Dreval Kostiantyn , Tryndyak Volodymyr , Orisakwe Orish E. , Ross Sharon A. , Beland Frederick A. , Pogribny Igor P.
Published: April 2023

Gene expression and gene-specific histone H4 lysine 16 acetylation of cell death-related genes in the livers of mice fed with choline- and folate-deficient diet.
Figure S4 from Inhibition of the Cell Death Pathway in Nonalcoholic Steatohepatitis (NASH)-Related Hepatocarcinogenesis Is Associated with Histone H4 lysine 16 Deacetylation
Authors: de Conti Aline , Dreval Kostiantyn , Tryndyak Volodymyr , Orisakwe Orish E. , Ross Sharon A. , Beland Frederick A. , Pogribny Igor P.
Published: April 2023

Expression of chromatin-modifying genes in the livers of control mice and STAM mice.
Supplemental Table 1 from PRAS40 Phosphorylation Correlates with Insulin-Like Growth Factor-1 Receptor-Induced Resistance to Epidermal Growth Factor Receptor Inhibition in Head and Neck Cancer Cells
Authors: Dougherty Michael I. , Lehman Christine E. , Spencer Adam , Mendez Rolando E. , David Abel P. , Taniguchi Linnea E. , Wulfkuhle Julie , Petricoin Emanuel F. , Gioeli Daniel , Jameson Mark J.
Published: April 2023

Supplemental Table 1: The percent rescue of cell viability following IGF1R activation. Percent rescue was determined for each sensitive cell line by comparing cell viability following treatment with gefitinib and desIGF1 (Gef+IGF1) to gefitinib alone (Gef). Percentages displayed in bold represent significant rescue with p<0.05 as determined by Tukey test.
Figure S1 from Inhibition of the Cell Death Pathway in Nonalcoholic Steatohepatitis (NASH)-Related Hepatocarcinogenesis Is Associated with Histone H4 lysine 16 Deacetylation
Authors: de Conti Aline , Dreval Kostiantyn , Tryndyak Volodymyr , Orisakwe Orish E. , Ross Sharon A. , Beland Frederick A. , Pogribny Igor P.
Published: April 2023

Control for Western blot equal protein loading.
Supplementary Table 5 from A YAP/TAZ-Regulated Molecular Signature Is Associated with Oral Squamous Cell Carcinoma
Authors: Hiemer Samantha E. , Zhang Liye , Kartha Vinay K. , Packer Trevor S. , Almershed Munirah , Noonan Vikki , Kukuruzinska Maria , Bais Manish V. , Monti Stefano , Varelas Xaralabos
Published: April 2023

Supplementary Table 5. Gene list from the cluster analysis in Fig 5B.
Supplementary Table 2 from A YAP/TAZ-Regulated Molecular Signature Is Associated with Oral Squamous Cell Carcinoma
Authors: Hiemer Samantha E. , Zhang Liye , Kartha Vinay K. , Packer Trevor S. , Almershed Munirah , Noonan Vikki , Kukuruzinska Maria , Bais Manish V. , Monti Stefano , Varelas Xaralabos
Published: April 2023

Supplementary Table 2. Antibodies used in the study.
Supplementary Table 1 from A YAP/TAZ-Regulated Molecular Signature Is Associated with Oral Squamous Cell Carcinoma
Authors: Hiemer Samantha E. , Zhang Liye , Kartha Vinay K. , Packer Trevor S. , Almershed Munirah , Noonan Vikki , Kukuruzinska Maria , Bais Manish V. , Monti Stefano , Varelas Xaralabos
Published: April 2023

Supplementary Table 1. RNAi used in the study.
Supplementary Figure S5 from A YAP/TAZ-Regulated Molecular Signature Is Associated with Oral Squamous Cell Carcinoma
Authors: Hiemer Samantha E. , Zhang Liye , Kartha Vinay K. , Packer Trevor S. , Almershed Munirah , Noonan Vikki , Kukuruzinska Maria , Bais Manish V. , Monti Stefano , Varelas Xaralabos
Published: April 2023

Supplementary Figure S5. Box plots showing the expression of the YAP/TAZ-regulated genes.
Supplementary Figure S4 from A YAP/TAZ-Regulated Molecular Signature Is Associated with Oral Squamous Cell Carcinoma
Authors: Hiemer Samantha E. , Zhang Liye , Kartha Vinay K. , Packer Trevor S. , Almershed Munirah , Noonan Vikki , Kukuruzinska Maria , Bais Manish V. , Monti Stefano , Varelas Xaralabos
Published: April 2023

Supplementary Figure S4. Correlation of YAP/TAZ activity with respect to tumor grade and stage using ASSIGN.
Supplementary Figure S2 from A YAP/TAZ-Regulated Molecular Signature Is Associated with Oral Squamous Cell Carcinoma
Authors: Hiemer Samantha E. , Zhang Liye , Kartha Vinay K. , Packer Trevor S. , Almershed Munirah , Noonan Vikki , Kukuruzinska Maria , Bais Manish V. , Monti Stefano , Varelas Xaralabos
Published: April 2023

Supplementary Figure S2. Additional immunoblots showing YAP and pS127-YAP levels in OSCC tumors.
Supplementary Figure from USP22 Interacts with PALB2 and Promotes Chemotherapy Resistance via Homologous Recombination of DNA Double-Strand Breaks
Authors: Nardi Isaac K. , Stark Jeremy M. , Larsen Adrien , Salgia Ravi , Raz Dan J.
Published: April 2023

Supplementary Figure 1
Supplemental Figures 1-7 from 14-3-3σ Contributes to Radioresistance By Regulating DNA Repair and Cell Cycle via PARP1 and CHK2
Authors: Chen Yifan , Li Zhaomin , Dong Zizheng , Beebe Jenny , Yang Ke , Fu Liwu , Zhang Jian-Ting
Published: April 2023

Figure S1. 14-3-3Ïƒ contributes to IR resistance. Figure S2. 14-3-3Ïƒ contributes to IR resistance in H1299 cells. Figure S3. 14-3-3Ïƒ modulates IR-induced Î³-H2AX in H1299 cells. Figure S4. 14-3-3Ïƒ promotes NHEJ but not HR repair of DSBs. Figure S5. Role of PARP1 in DNA-PKcs recruitment. Figure S6. 14-3-3Ïƒ regulation of Chk2 expression in H1299 cells. Figure S7. PARP1 regulates Chk2 expression but not vice versa.
Supplementary Figure 5 from p53–Pirh2 Complex Promotes Twist1 Degradation and Inhibits EMT
Authors: Yang-Hartwich Yang , Tedja Roslyn , Roberts Cai M. , Goodner-Bingham Jamie , Cardenas Carlos , Gurea Marta , Sumi Natalia J. , Alvero Ayesha B. , Glackin Carlotta A. , Mor Gil
Published: April 2023

The over expression of Î"b-Twist1 in R182 cells (p53-high/Twist1- ) was detected by Western blot.
Table S1-S5 from Molecular Portrait of Hypoxia in Breast Cancer: A Prognostic Signature and Novel HIF-Regulated Genes
Authors: Ye I. Chae , Fertig Elana J. , DiGiacomo Josh W. , Considine Michael , Godet Inês , Gilkes Daniele M.
Published: April 2023

Supplemental Tables
Supplementary Figure Legends from Molecular Portrait of Hypoxia in Breast Cancer: A Prognostic Signature and Novel HIF-Regulated Genes
Authors: Ye I. Chae , Fertig Elana J. , DiGiacomo Josh W. , Considine Michael , Godet Inês , Gilkes Daniele M.
Published: April 2023

Supplementary Figure Legends
Supplementary figures and captions 1-5 from Optical Imaging of Glucose Uptake and Mitochondrial Membrane Potential to Characterize Her2 Breast Tumor Metabolic Phenotypes
Authors: Madonna Megan C. , Fox Douglas B. , Crouch Brian T. , Lee Jihong , Zhu Caigang , Martinez Amy F. , Alvarez James V. , Ramanujam Nirmala
Published: April 2023

Supplementary Figure 1: 3D Rendering of mammosphere stained with 2-NBDG and TMRE. Supplementary Figure 2: Western blot confirms loss of Her2 expression following withdrawal of Dox in media conditions. Supplementary Figure 3: Quantification of immunohistochemistry results confirm changes in proliferation and apoptosis. Supplementary Figure 4: Average 2-NBDG and TMRE per mammosphere and group across each time point. Supplementary Figure 5: Annexin V and TMRE flow cytometry show increased TMRE is independent of increased apoptosis.
Supplementary Table S1 from Global Increase of p16INK4a in APC-Deficient Mouse Liver Drives Clonal Growth of p16INK4a-Negative Tumors
Authors: Ueberham Elke , Glöckner Pia , Göhler Claudia , Straub Beate K. , Teupser Daniel , Schönig Kai , Braeuning Albert , Höhn Anne Kathrin , Jerchow Boris , Birchmeier Walter , Gaunitz Frank , Arendt Thomas , Sansom Owen , Gebhardt Rolf , Ueberham Uwe
Published: April 2023

List of transgenic mice used in the study.
Supplemental Figure 4 from Genomic cfDNA Analysis of Aqueous Humor in Retinoblastoma Predicts Eye Salvage: The Surrogate Tumor Biopsy for Retinoblastoma
Authors: Berry Jesse L. , Xu Liya , Kooi Irsan , Murphree A. Linn , Prabakar Rishvanth K. , Reid Mark , Stachelek Kevin , Le Bao Han A. , Welter Lisa , Reiser Bibiana J. , Chévez-Barrios Patricia , Jubran Rima , Lee Thomas C. , Kim Jonathan W. , Kuhn Peter , Cobrinik David , Hicks James
Published: April 2023

Supplemental Figure 4, online only: Initial Copy Number Alteration (CNA) profile from eyes that were successfully salvaged with treatment
Supplementary Table S1-S4 from Targeting the MIF/CXCR7/AKT Signaling Pathway in Castration-Resistant Prostate Cancer
Authors: Rafiei Shahrzad , Gui Bin , Wu Jiaxin , Liu X. Shirley , Kibel Adam S. , Jia Li
Published: April 2023

Supplementary Tables
Supplemental Figures 1-5 from Calcium Sensor, NCS-1, Promotes Tumor Aggressiveness and Predicts Patient Survival
Authors: Moore Lauren M. , England Allison , Ehrlich Barbara E. , Rimm David L.
Published: April 2023

Figure 1: NCS-1 and its Known Binding Partners: This web diagram illustrates the binding partners of NCS-1. Figure 2: Assessment of the effect of NCS-1 on Motility: Representative photomicrographs from scratch motility assays for A. Figure 3: NCS-1 May Promote Tumor Aggressiveness by Altering Invasion and Chemotaxis: Representative photomicrographs from Transwell invasion assays show that overexpression of NCS-1 increases invasion in both A. MCF-7 and B. MB-231 cell lines. Figure 4: NCS-1 May Promote Tumor Aggressiveness by Altering Adhesion: Representative images for Collagen IV cell-adhesion assay for A. MCF-7 and B. MB-231 cell lines. Figure 5: Assessment of NCS-1 in Normal Breast Tissue. A. AQUA scores for NCS-1 in the tumor mask (y-axis) for each individual patient (x-axis). B. Normal distribution of NCS-1 AQUA scores for collective normal breast tissue cohort.
Supplemental Data from Calcium Sensor, NCS-1, Promotes Tumor Aggressiveness and Predicts Patient Survival
Authors: Moore Lauren M. , England Allison , Ehrlich Barbara E. , Rimm David L.
Published: April 2023

Figure 1: NCS-1 and its Known Binding Partners. Figure 2: Assessment of the effect of NCS-1 on Motility. Figure 3: NCS-1 May Promote Tumor Aggressiveness by Altering Invasion and Chemotaxis. Figure 4: NCS-1 May Promote Tumor Aggressiveness by Altering Adhesion. Figure 5: Assessment of NCS-1 in Normal Breast Tissue. Figure 6: Validation of Prognostic Value of NCS-1 mRNA using SurvExpress, a biomarker validation tool with publicly available cancer datasets.
Supplementary Figures 1-5 from β2-adrenoreceptor Signaling Increases Therapy Resistance in Prostate Cancer by Upregulating MCL1
Authors: Hassan Sazzad , Pullikuth Ashok , Nelson Kyle C. , Flores Anabel , Karpova Yelena , Baiz Daniele , Zhu Sinan , Sui Guangchao , Huang Yue , Choi Young A. , D'Agostino Ralph , Hemal Ashok , von Holzen Urs , Debinski Waldemar , Kulik George
Published: April 2023

S1. Epinephrine inhibits apoptosis by upregulatingMCL1in prostate cancer cells. S2.Epinephrine upregulates MCL1via the ADRB2/PKA pathway S3.C4-2shMCL1 cells with inducible expression of shRNAtargeting MCL1. S4. Effects of chemotherapy drugs on MCL1 expression in prostate cancer cells. S5. The loss of MCL1 expression in cells treated with chemotherapeuticdrugsis restored via ADRB2/PKA signaling.
Supplementary Figure 5 from Adaptation to HIF1α Deletion in Hypoxic Cancer Cells by Upregulation of GLUT14 and Creatine Metabolism
Authors: Valli Alessandro , Morotti Matteo , Zois Christos E. , Albers Patrick K. , Soga Tomoyoshi , Feldinger Katharina , Fischer Roman , Frejno Martin , McIntyre Alan , Bridges Esther , Haider Syed , Buffa Francesca M. , Baban Dilair , Rodriguez Miguel , Yanes Oscar , Whittington Hannah J. , Lake Hannah A. , Zervou Sevasti , Lygate Craig A. , Kessler Benedikt M. , Harris Adrian L.
Published: April 2023

S5. Statistical significance for mRNA PCR data.
Supplementary Figure 4 from Adaptation to HIF1α Deletion in Hypoxic Cancer Cells by Upregulation of GLUT14 and Creatine Metabolism
Authors: Valli Alessandro , Morotti Matteo , Zois Christos E. , Albers Patrick K. , Soga Tomoyoshi , Feldinger Katharina , Fischer Roman , Frejno Martin , McIntyre Alan , Bridges Esther , Haider Syed , Buffa Francesca M. , Baban Dilair , Rodriguez Miguel , Yanes Oscar , Whittington Hannah J. , Lake Hannah A. , Zervou Sevasti , Lygate Craig A. , Kessler Benedikt M. , Harris Adrian L.
Published: April 2023

S4. Hypoxic regulation of glucose transporters and creatine kinases validation by PCR and western blot analysis.
Figure S2, A from Diffuse Intrinsic Pontine Glioma Cells Are Vulnerable to Mitotic Abnormalities Associated with BMI-1 Modulation
Authors: Senthil Kumar Shiva , Sengupta Satarupa , Zhu Xiaoting , Mishra Deepak Kumar , Phoenix Timothy , Dyer Lisa , Fuller Christine , Stevenson Charles B. , DeWire Mariko , Fouladi Maryam , Drissi Rachid
Published: April 2023

A, Scheme representing the experiment design of PTC596 treatment, drug wash-off and time points to evaluate PTC596 activity by immunoblot analysis of BMI-1, H2AK119Ub (Day 4) and cell growth by WST-1 assay (Days 8 and 11) in HFF, CCHMC-DIPG-1 and CCHMC-DIPG-2 cells. β-actin and total H2A served as loading control. Error bars represent the SD from triplicates.
Significantly differentially expressed genes from Histone H3.3K27M Represses p16 to Accelerate Gliomagenesis in a Murine Model of DIPG
Authors: Cordero Francisco J. , Huang Zhiqing , Grenier Carole , He Xingyao , Hu Guo , McLendon Roger E. , Murphy Susan K. , Hashizume Rintaro , Becher Oren J.
Published: April 2023

List of all significantly differentially expressed genes in empty vector vs H3.3K27M tumor RNA-Seq analysis.
Table S1 from T-Cell Deletion of MyD88 Connects IL17 and IκBζ to RAS Oncogenesis
Authors: Cataisson Christophe , Salcedo Rosalba , Michalowski Aleksandra M. , Klosterman Mary , Naik Shruti , Li Luowei , Pan Michelle J. , Sweet Amalia , Chen Jin-Qiu , Kostecka Laurie G. , Karwan Megan , Smith Loretta , Dai Ren-Ming , Stewart C. Andrew , Lyakh Lyudmila , Hsieh Wang-Ting , Khan Asra , Yang Howard , Lee Maxwell , Trinchieri Giorgio , Yuspa Stuart H.
Published: April 2023

Supplemental table 1: RNA profiling of differentially expressed genes in CD3+ sorted cell population isolated from MyD88fl/fl and MyD88CD4-Cre chronically TPA-treated skins. (A) List of genes from RNA profiling that are significantly affected (by at least 1.3-fold change and FDR <5%) by MyD88 deficiency in T cells. (B) Ingenuity Pathways Analysis (IPA) of top significant genes.
Supplementary Materials from PPARδ Reprograms Glutamine Metabolism in Sorafenib-Resistant HCC
Authors: Kim Mi-Jin , Choi Yeon-Kyung , Park Soo Young , Jang Se Young , Lee Jung Yi , Ham Hye Jin , Kim Byung-Gyu , Jeon Hui-Jeon , Kim Ji-Hyun , Kim Jung-Guk , Lee In-Kyu , Park Keun-Gyu
Published: April 2023

Supplementary Materials shows the figure legends of Supplementary figures and Tables.
Supplementary Figure S5 from Estrogen-Induced Apoptosis in Breast Cancers Is Phenocopied by Blocking Dephosphorylation of Eukaryotic Initiation Factor 2 Alpha (eIF2α) Protein
Authors: Sengupta Surojeet , Sevigny Catherine M. , Bhattacharya Poulomi , Jordan V. Craig , Clarke Robert
Published: April 2023

Fulvestrant potentiates the apoptotic effect of salubrinal in MCF7:5C and LCC9 cells.
Supplemental Figures 1-3 and Supplemental Tables 1-4 from Real-Time Transferrin-Based PET Detects MYC-Positive Prostate Cancer
Authors: Aggarwal Rahul , Behr Spencer C. , Paris Pamela L. , Truillet Charles , Parker Matthew F.L. , Huynh Loc T. , Wei Junnian , Hann Byron , Youngren Jack , Huang Jiaoti , Premasekharan Gayatri , Ranatunga Nimna , Chang Emily , Gao Kenneth T. , Ryan Charles J. , Small Eric J. , Evans Michael J.
Published: April 2023

Supplemental Figure 1: Biodistribution data reflecting the accumulation of 68Ga-citrate over time in the tissues of male nu/nu mice bearing PC3 xenografts. Peak radiotracer uptake was observed at 4 hours post injection. Supplemental Figure 2: Biodistribution data reflecting the accumulation of 68Ga-citrate at 4 hours post injection in the tissues of male nu/nu mice bearing 22Rv1 xenografts. Supplemental Figure 3: Biodistribution data collected 4 hours post injection of 68Ga-citrate in male nu/nu mice bearing subcutaneous PC3 xenografts, and 48 hours post injection of 89Zr-Tf in male nu/nu mice with subcutaneous PC3 xenografts. Supplemental Figure 4. BET inhibitors suppress MYC and transferrin uptake in MYC positive prostate cancer cell lines. Supplemental Figure 5: Biodistribution data collected 4 hours post injection of 68Ga-Tf in male nu/nu mice bearing subcutaneous PC3 or 22Rv1 xenografts. Mice were treated with vehicle, (+)-JQ1 (25 mg/kg, BID), or iBET (50 mg/kg, daily oral gavage) for 5 days prior to radiotracer injection. Supplemental Figure 6: Representative PET data collected 4 hours post injection of 68Ga-citrate or 48 hours post injection of 89Zr-Tf in male nu/nu mice bearing subcutaneous 22Rv1 xenografts. Supplemental Figure 7: Paired PET imaging plus CT-guided biopsy of tracer-avid liver metastasis in patient-003 with mCRPC. Supplemental Figure 8: H&E staining of the PDX tissue isolated from the liver metastasis of patient-003 shows morphological features consistent with the liver biopsy. Supplemental Figure 9. Biodistribution data acquired 4 hours post injection of 68Ga-citrate shows the accumulation of the radiotracer in the PDX tissue and selected normal mouse tissues. Supplemental Table 1. A summary of the tumor:blood and tumor: muscle ratios for 68Ga-citrate Supplemental Table 2. A summary of the patient characteristics in this study. Supplemental Table 3. A summary of the test/re-test data for 68Ga-citrate in normal tissues. Data are presented as SUVmax. Supplementary Table 4. A summary of the histological subclassifications for the prostate cancer biopsies acquired during this study.
Supplementary materials from Alectinib Resistance in ALK-Rearranged Lung Cancer by Dual Salvage Signaling in a Clinically Paired Resistance Model
Authors: Tsuji Takahiro , Ozasa Hiroaki , Aoki Wataru , Aburaya Shunsuke , Funazo Tomoko , Furugaki Koh , Yoshimura Yasushi , Ajimizu Hitomi , Okutani Ryoko , Yasuda Yuto , Nomizo Takashi , Uemasu Kiyoshi , Hasegawa Koichi , Yoshida Hironori , Yagi Yoshitaka , Nagai Hiroki , Sakamori Yuichi , Ueda Mitsuyoshi , Hirai Toyohiro , Kim Young Hak
Published: April 2023

Supplementary Figure S1-S6 and Table S1-S3
Revised supplementary Table 2 from Genome-Wide Analysis Identifies MEN1 and MAX Mutations and a Neuroendocrine-Like Molecular Heterogeneity in Quadruple WT GIST
Authors: Pantaleo Maria A. , Urbini Milena , Indio Valentina , Ravegnini Gloria , Nannini Margherita , De Luca Matilde , Tarantino Giuseppe , Angelini Sabrina , Gronchi Alessandro , Vincenzi Bruno , Grignani Giovanni , Colombo Chiara , Fumagalli Elena , Gatto Lidia , Saponara Maristella , Ianni Manuela , Paterini Paola , Santini Donatella , Pirini M. Giulia , Ceccarelli Claudio , Altimari Annalisa , Gruppioni Elisa , Renne Salvatore L. , Collini Paola , Stacchiotti Silvia , Brandi Giovanni , Casali Paolo G. , Pinna Antonio D. , Astolfi Annalisa , Biasco Guido
Published: April 2023

Supplementary Table 2. The most important miRNA predicted as potential regulators of Neuroactive ligand-receptor interaction signature genes.
Supplementary Figure 1 from Blockade of AP-1 Potentiates Endocrine Therapy and Overcomes Resistance
Authors: Malorni Luca , Giuliano Mario , Migliaccio Ilenia , Wang Tao , Creighton Chad J. , Lupien Mathieu , Fu Xiaoyong , Hilsenbeck Susan G. , Healy Nuala , De Angelis Carmine , Mazumdar Abhijit , Trivedi Meghana V. , Massarweh Suleiman , Gutierrez Carolina , De Placido Sabino , Jeselsohn Rinath , Brown Myles , Brown Powel H. , Osborne C. Kent , Schiff Rachel
Published: April 2023

Genes up-regulated in Tam-R and putatively associated with EGF-induced ER binding sites (genes containing an AP-1 motif are shown in bold)
Figure S4 from Molecular Signature and Mechanisms of Hepatitis D Virus–Associated Hepatocellular Carcinoma
Authors: Diaz Giacomo , Engle Ronald E. , Tice Ashley , Melis Marta , Montenegro Stephanie , Rodriguez-Canales Jaime , Hanson Jeffrey , Emmert-Buck Michael R. , Bock Kevin W. , Moore Ian N. , Zamboni Fausto , Govindarajan Sugantha , Kleiner David E. , Farci Patrizia
Published: April 2023

Clusters of the 37 genes involved in the cell cycle and differentially expressed in malignant hepatocytes derived from HDV-HCC.
Text S3 from The Landscape of Isoform Switches in Human Cancers
Authors: Vitting-Seerup Kristoffer , Sandelin Albin
Published: April 2023

Analysis of the effect of potential biases in TCGA data.
Text S1 from The Landscape of Isoform Switches in Human Cancers
Authors: Vitting-Seerup Kristoffer , Sandelin Albin
Published: April 2023

Introduction to usage of the R package IsoformSwitchAnalyzeR (vignette).
Supplementary Tables 1-7 from A Leukocyte Infiltration Score Defined by a Gene Signature Predicts Melanoma Patient Prognosis
Authors: Zhao Yanding , Schaafsma Evelien , Gorlov Ivan P. , Hernando Eva , Thomas Nancy E. , Shen Ronglai , Turk Mary Jo , Berwick Marianne , Amos Christopher I. , Cheng Chao
Published: April 2023

Table S1. Summary of the datasets Table S2. Immune related genes' correlation with ImmuneScore Table S3. 25 genes PC1 loading coefficient Table S4. Primary tumor mutation's association with LIS Table S5. Metastatic tumor mutation's association with LIS Table S6. Primary tumor CNV's association with LIS Table S7. Metastatic tumor CNV's association with LIS
Supplemental Figures 1 - 3 from Identification and Characterization of Oncogenic SOS1 Mutations in Lung Adenocarcinoma
Authors: Cai Diana , Choi Peter S. , Gelbard Maya , Meyerson Matthew
Published: April 2023

Figure S1: SOS1-mutant AALE cells grow in an anchorage-independent manner and have higher levels of MEK phosphorylation Figure S2: Mutation of a highly conserved site in the DH domain does not necessarily abolish SOS1 N233Y induced transformation of NIH-3T3 Figure S3: Measurement of erlotinib response in SOS1 N233Y expressing cells
Table S1 from CREBBP/EP300 Bromodomain Inhibition Affects the Proliferation of AR-Positive Breast Cancer Cell Lines
Authors: Garcia-Carpizo Veronica , Ruiz-Llorente Sergio , Sarmentero Jacinto , González-Corpas Ana , Barrero Maria J.
Published: April 2023

Oligonucleotides used in this study
Figure S7 from CREBBP/EP300 Bromodomain Inhibition Affects the Proliferation of AR-Positive Breast Cancer Cell Lines
Authors: Garcia-Carpizo Veronica , Ruiz-Llorente Sergio , Sarmentero Jacinto , González-Corpas Ana , Barrero Maria J.
Published: April 2023

Analysis of CREBBP/EP300 mutations and gene expression across different types of cancer. (a) Percentage of cases containing mutations in CREBBP or EP300 in different types of cancers according to TCGA data. (b) Levels of AR mRNA in TCGA ER(-)/PR(-) apocrine (A) and non-apocrine (NA) breast tumors. (c) Levels of CREBBP or EP300 mRNA in TCGA breast cancer samples including normal tissue (N), all tumors (T), ER(-)/PR(-) apocrine (A) and non-apocrine (NA) tumors. (d) Levels of CREBBP or EP300 mRNA in TCGA prostate cancer samples including normal tissue (N) and all tumors (T). (e) Correlation between AR and CREBBP or EP300 mRNA levels in all TCGA breast cancer tumors. (f) Correlation between AR and CREBBP or EP300 mRNA levels in all TCGA prostate cancer tumors.
Figure S6 from CREBBP/EP300 Bromodomain Inhibition Affects the Proliferation of AR-Positive Breast Cancer Cell Lines
Authors: Garcia-Carpizo Veronica , Ruiz-Llorente Sergio , Sarmentero Jacinto , González-Corpas Ana , Barrero Maria J.
Published: April 2023

Selection of potential target genes of CREBBP/EP300 bromodomain inhibitors in LNCaP. Genomic tracks showing the levels of H3K27ac, AR and mRNA levels in LNCaP cells surrounding known AR-target genes in LNCaP cells. Right insets correspond to magnifications of the genomic regions labeled in grey. Intervals corresponding to SEs are also shown.
Supplementary Figure Legends from p21CIP1 Promotes Mammary Cancer–Initiating Cells via Activation of Wnt/TCF1/CyclinD1 Signaling
Authors: Benard Outhiriaradjou , Qian Xia , Liang Huizhi , Ren Zuen , Suyama Kimita , Norton Larry , Hazan Rachel B.
Published: April 2023

Supplementary Figure Legends
Figure S2 from p21CIP1 Promotes Mammary Cancer–Initiating Cells via Activation of Wnt/TCF1/CyclinD1 Signaling
Authors: Benard Outhiriaradjou , Qian Xia , Liang Huizhi , Ren Zuen , Suyama Kimita , Norton Larry , Hazan Rachel B.
Published: April 2023

Figure S2. LEF1 knockdown in PyMT cells does not inhibit Wnt signaling or mammosphere formation.
Figure S1 from p21CIP1 Promotes Mammary Cancer–Initiating Cells via Activation of Wnt/TCF1/CyclinD1 Signaling
Authors: Benard Outhiriaradjou , Qian Xia , Liang Huizhi , Ren Zuen , Suyama Kimita , Norton Larry , Hazan Rachel B.
Published: April 2023

Figure S1. The effect of p21 knockout on Wnt signal transduction.
Supplemental Table 1 B from Elevated V–ATPase Activity Following PTEN Loss Is Required for Enhanced Oncogenic Signaling in Breast Cancer
Authors: Mohammad Amro H. , Kim Sung-Hoon , Bertos Nicholas , El-Assaad Wissal , Nandi Ipshita , Smith Harvey , Yang Jieyi , Chen Owen J. , Gamache Isabelle , Rao Trisha , Gagnon Bruno , Gruosso Tina , Tremblay Michel L. , Sonenberg Nahum , Guiot Marie-Christine , Muller William , Park Morag , Teodoro Jose G.
Published: April 2023

Clinical parameters of patients from whom tissue microarrays were acquired for P-Akt staining
Supplemental Figure 3 from Elevated V–ATPase Activity Following PTEN Loss Is Required for Enhanced Oncogenic Signaling in Breast Cancer
Authors: Mohammad Amro H. , Kim Sung-Hoon , Bertos Nicholas , El-Assaad Wissal , Nandi Ipshita , Smith Harvey , Yang Jieyi , Chen Owen J. , Gamache Isabelle , Rao Trisha , Gagnon Bruno , Gruosso Tina , Tremblay Michel L. , Sonenberg Nahum , Guiot Marie-Christine , Muller William , Park Morag , Teodoro Jose G.
Published: April 2023

This figure contains clinical data that complement the observations made in Figure 4.
Supplemental Figure 2 from Elevated V–ATPase Activity Following PTEN Loss Is Required for Enhanced Oncogenic Signaling in Breast Cancer
Authors: Mohammad Amro H. , Kim Sung-Hoon , Bertos Nicholas , El-Assaad Wissal , Nandi Ipshita , Smith Harvey , Yang Jieyi , Chen Owen J. , Gamache Isabelle , Rao Trisha , Gagnon Bruno , Gruosso Tina , Tremblay Michel L. , Sonenberg Nahum , Guiot Marie-Christine , Muller William , Park Morag , Teodoro Jose G.
Published: April 2023

This figure contains bright-field counterparts of LysoTracker images. This figure also contains HER2 immunostaining after PRR knockdown in SKBR3 cells.
Supplemental Figure 1 from Elevated V–ATPase Activity Following PTEN Loss Is Required for Enhanced Oncogenic Signaling in Breast Cancer
Authors: Mohammad Amro H. , Kim Sung-Hoon , Bertos Nicholas , El-Assaad Wissal , Nandi Ipshita , Smith Harvey , Yang Jieyi , Chen Owen J. , Gamache Isabelle , Rao Trisha , Gagnon Bruno , Gruosso Tina , Tremblay Michel L. , Sonenberg Nahum , Guiot Marie-Christine , Muller William , Park Morag , Teodoro Jose G.
Published: April 2023

This figure compares ATP6AP2 expression in normal and tumour human prostate and breast tissues.
Supplemental Table 1 from BRCA1-Interacting Protein OLA1 Requires Interaction with BARD1 to Regulate Centrosome Number
Authors: Yoshino Yuki , Qi Huicheng , Fujita Hiroki , Shirota Matsuyuki , Abe Shun , Komiyama Yuhei , Shindo Kazuha , Nakayama Masahiro , Matsuzawa Ayako , Kobayashi Akihiro , Ogoh Honami , Watanabe Toshio , Ishioka Chikashi , Chiba Natsuko
Published: April 2023

Summary of biological functions of OLA1 mutants.
Figure S5 from BRCA1-Interacting Protein OLA1 Requires Interaction with BARD1 to Regulate Centrosome Number
Authors: Yoshino Yuki , Qi Huicheng , Fujita Hiroki , Shirota Matsuyuki , Abe Shun , Komiyama Yuhei , Shindo Kazuha , Nakayama Masahiro , Matsuzawa Ayako , Kobayashi Akihiro , Ogoh Honami , Watanabe Toshio , Ishioka Chikashi , Chiba Natsuko
Published: April 2023

Centrosome amplification induced by overexpression of BRCA1.
Figure S4 from BRCA1-Interacting Protein OLA1 Requires Interaction with BARD1 to Regulate Centrosome Number
Authors: Yoshino Yuki , Qi Huicheng , Fujita Hiroki , Shirota Matsuyuki , Abe Shun , Komiyama Yuhei , Shindo Kazuha , Nakayama Masahiro , Matsuzawa Ayako , Kobayashi Akihiro , Ogoh Honami , Watanabe Toshio , Ishioka Chikashi , Chiba Natsuko
Published: April 2023

Supplementary Figure 4. BARD1 expression in Hs578T cells transfected with BARD1 siRNA and expression vector.
Supplemental figures and movie description from The Role of Alcohol-Induced Golgi Fragmentation for Androgen Receptor Signaling in Prostate Cancer
Authors: Manca Sonia , Frisbie Cole P. , LaGrange Chad A. , Casey Carol A. , Riethoven Jean-Jack M. , Petrosyan Armen
Published: April 2023

S1. Determination of HDAC6 immunofluorescence in the nuclei of PCa tissues. S2. EtOH induces Golgi fragmentation in 22Rv1 cells. S3. (A) The AR W-B of the cytoplasmic and nuclear fractions isolated from LNCaP (c-19) cells. S4. Colocalization of GM130 and GSK3β in LNCaP cells. Movie S1. 3D SIM animation of the control LNCaP (c-26) cells stained with giantin (red). Movie S2. 3D SIM animation of the LNCaP (c-26) cells after EtOH treatment (35 mM for 96 h) stained with giantin (red).
Supplementary Methods, Figure Legends from FoxO3a Mediates the Inhibitory Effects of the Antiepileptic Drug Lamotrigine on Breast Cancer Growth
Authors: Pellegrino Michele , Rizza Pietro , Nigro Alessandra , Ceraldi Rosangela , Ricci Elena , Perrotta Ida , Aquila Saveria , Lanzino Marilena , Andò Sebastiano , Morelli Catia , Sisci Diego
Published: April 2023

Supplementary Methods, Figure Legends
Supplementary Figures Legend from PKCϵ Controls Mitotic Progression by Regulating Centrosome Migration and Mitotic Spindle Assembly
Authors: Martini Silvia , Soliman Tanya , Gobbi Giuliana , Mirandola Prisco , Carubbi Cecilia , Masselli Elena , Pozzi Giulia , Parker Peter J. , Vitale Marco
Published: April 2023

Here are described the Supplementary Figures from Figure S1 to Figure S4.
Supplementary Figure S4 from FoxO3a Mediates the Inhibitory Effects of the Antiepileptic Drug Lamotrigine on Breast Cancer Growth
Authors: Pellegrino Michele , Rizza Pietro , Nigro Alessandra , Ceraldi Rosangela , Ricci Elena , Perrotta Ida , Aquila Saveria , Lanzino Marilena , Andò Sebastiano , Morelli Catia , Sisci Diego
Published: April 2023

LTG effects on several hallmarks of apoptosis, necrosis and necroptosis.
Supplementary Methods from GPR56 Drives Colorectal Tumor Growth and Promotes Drug Resistance through Upregulation of MDR1 Expression via a RhoA-Mediated Mechanism
Authors: Zhang Sheng , Chatterjee Treena , Godoy Carla , Wu Ling , Liu Qingyun J. , Carmon Kendra S.
Published: April 2023

Methods pertaining to experiments included in supplement and not described in manuscript.
Supplemental Table 1 and Suppl Figures 1-6 from Endothelial Cells Promote Colorectal Cancer Cell Survival by Activating the HER3-AKT Pathway in a Paracrine Fashion
Authors: Wang Rui , Bhattacharya Rajat , Ye Xiangcang , Fan Fan , Boulbes Delphine R. , Ellis Lee M.
Published: April 2023

Supplemental Table 1 for cell line authentications Table S1. Cell Authentication by Short Tandem Repeat (STR) Test Supplementary Figure 1. LPEC-1 CM activated HER3-AKT and induced cell growth in different CRC cell lines. Supplementary Figure 2. CM of ECs from different organs activated AKT-HER3 and increased cell growth in CRC cells. Supplementary Figure 3. MET and EGFR did not mediate HER3 and AKT phosphorylation in HCP-1 CRC cells. Supplementary Figure 4. LPEC-1 CM induced HER3 phosphorylation in HCP-1 cells independent of HER2. Supplementary Figure 5. HER3 antibody MM-121 blocked LPEC-1 CM-induced AKT activation and chemoresistance in CRC cells. Supplementary Figure 6. LPEC-1 CM increased CRC cell growth in vivo.
Supplementary Figure 7 from Epigenetic Regulation of ZBTB18 Promotes Glioblastoma Progression
Authors: Fedele Vita , Dai Fangping , Masilamani Anie P. , Heiland Dieter H. , Kling Eva , Gätjens-Sanchez Ana M. , Ferrarese Roberto , Platania Leonardo , Doostkam Soroush , Kim Hyunsoo , Nelander Sven , Weyerbrock Astrid , Prinz Marco , Califano Andrea , Iavarone Antonio , Bredel Markus , Carro Maria S.
Published: April 2023

ZBTB18 promoter methylation analysis.
Supplementary Table 3 from Inhibition of Ciliogenesis Promotes Hedgehog Signaling, Tumorigenesis, and Metastasis in Breast Cancer
Authors: Hassounah Nadia B. , Nunez Martha , Fordyce Colleen , Roe Denise , Nagle Ray , Bunch Thomas , McDermott Kimberly M.
Published: April 2023

Supplemental Table S3. Hedgehog, PI3KIAKT and RAS/MAPK pathway gene signatures.
Supplementary Table 2 from Inhibition of Ciliogenesis Promotes Hedgehog Signaling, Tumorigenesis, and Metastasis in Breast Cancer
Authors: Hassounah Nadia B. , Nunez Martha , Fordyce Colleen , Roe Denise , Nagle Ray , Bunch Thomas , McDermott Kimberly M.
Published: April 2023

Supplemental Table S2. Descriptive Statistics for Progression-free Survival Times for the Ift20/PyMT+ Tumor Growth Study.
Supplementary Data from Inhibition of Ciliogenesis Promotes Hedgehog Signaling, Tumorigenesis, and Metastasis in Breast Cancer
Authors: Hassounah Nadia B. , Nunez Martha , Fordyce Colleen , Roe Denise , Nagle Ray , Bunch Thomas , McDermott Kimberly M.
Published: April 2023

Fig. 81. Inhibition of ciliogenesis is not sufficient to initiate mammary tumorigenesis. Fig. 82. Inhibition of ciliogenesis in lft20fl/fi/PyMT +glands. Fig. S3 Inhibition of ciliogenesis does not result in increased frequency of pre-malignant lesions in the PyMT model of breast cancer. Fig. 84. Inhibition of ciliogenesis in isolated primary mammary epithelial cells. Fig. 85. Original western blots investigating p-ERK, p-AKT and GLI3 repressor levels for Figure 2. Fig. 86. Original western blot investigating GLI3R levels for Figure 3.
Supplementary Data from Pharmacologic Ascorbate Primes Pancreatic Cancer Cells for Death by Rewiring Cellular Energetics and Inducing DNA Damage
Authors: Buranasudja Visarut , Doskey Claire M. , Gibson Adrienne R. , Wagner Brett A. , Du Juan , Gordon David J. , Koppenhafer Stacia L. , Cullen Joseph J. , Buettner Garry R.
Published: April 2023

S1. There is differential susceptibility to P-AscH- across cell lines. S2. Bolus addition of hydrogen peroxide depletes intracellular ATP and NAD+ in MIA PaCa-2 and PANC-1 cells. S3. Pharmacological ascorbate depletes intracellular NADH in MIA PaCa-2 cells, but not in PANC-1, 339, and H6c7 cells. S4. Pharmacological inhibition of PARP1 by olaparib enhances the cytotoxicity of P-AscH- in MIA PaCa-2 cells. S5. A combination of P-AscH- and prexasertib synergistically inhibits cell proliferation of MIA PaCa-2 cells. Supplementary Table S1. Normal pancreatic cells are more resistant to P-AscH- than pancreatic cancer cells. Supplementary Table S2. The ED50's for depletion of ATP and NAD+ correlate with kcell for the removal of H2O2. Supplementary Table S3. The gene target and primer pairs used for QPCR.
Supplementary Information from Transient Telomerase Inhibition with Imetelstat Impacts DNA Damage Signals and Cell-Cycle Kinetics
Authors: Thompson Connor A.H. , Gu Alice , Yang Sunny Y. , Mathew Veena , Fleisig Helen B , Wong Judy M.Y.
Published: April 2023

Supplementary Figure 1. Imetelstat reduces cell number in telomerase positive cell lines in a dose-dependent manner following 7-day incubation. Supplementary Figure 2. Imetelstat inhibits telomerase activity in a dose dependent manner. Supplementary Figure 3. Secondary-antibody alone controls for imetelstat induced DNA damage foci. Supplementary Figure 4. Short-term Imetelstat treatment does not increase cell death. Supplementary Figure 5. KU55933 does not affect telomerase inhibition by imetelstat.
Supplementary Movie Legend from A Ca2+-ATPase Regulates E-cadherin Biogenesis and Epithelial–Mesenchymal Transition in Breast Cancer Cells
Authors: Dang Donna K. , Makena Monish Ram , Llongueras José P. , Prasad Hari , Ko Myungjun , Bandral Manuj , Rao Rajini
Published: April 2023

Legend for Supplementary Movies 1 and 2
Supplementary Table VI from Therapeutic Targeting of CD146/MCAM Reduces Bone Metastasis in Prostate Cancer
Authors: Zoni Eugenio , Astrologo Letizia , Ng Charlotte K.Y. , Piscuoglio Salvatore , Melsen Janine , Grosjean Joël , Klima Irena , Chen Lanpeng , Snaar-Jagalska Ewa B. , Flanagan Kenneth , van der Pluijm Gabri , Kloen Peter , Cecchini Marco G. , Kruithof-de Julio Marianna , Thalmann George N.
Published: April 2023

Enrichement analysis G0.
Supplementary Movie 2 from A Ca2+-ATPase Regulates E-cadherin Biogenesis and Epithelial–Mesenchymal Transition in Breast Cancer Cells
Authors: Dang Donna K. , Makena Monish Ram , Llongueras José P. , Prasad Hari , Ko Myungjun , Bandral Manuj , Rao Rajini
Published: April 2023

Supplementary Movie 2
Supplementary Table V from Therapeutic Targeting of CD146/MCAM Reduces Bone Metastasis in Prostate Cancer
Authors: Zoni Eugenio , Astrologo Letizia , Ng Charlotte K.Y. , Piscuoglio Salvatore , Melsen Janine , Grosjean Joël , Klima Irena , Chen Lanpeng , Snaar-Jagalska Ewa B. , Flanagan Kenneth , van der Pluijm Gabri , Kloen Peter , Cecchini Marco G. , Kruithof-de Julio Marianna , Thalmann George N.
Published: April 2023

Enrichement analysis for E2F.
Supplementary Movie 1 from A Ca2+-ATPase Regulates E-cadherin Biogenesis and Epithelial–Mesenchymal Transition in Breast Cancer Cells
Authors: Dang Donna K. , Makena Monish Ram , Llongueras José P. , Prasad Hari , Ko Myungjun , Bandral Manuj , Rao Rajini
Published: April 2023

Supplementary Movie 1
Supplementary Table II from Therapeutic Targeting of CD146/MCAM Reduces Bone Metastasis in Prostate Cancer
Authors: Zoni Eugenio , Astrologo Letizia , Ng Charlotte K.Y. , Piscuoglio Salvatore , Melsen Janine , Grosjean Joël , Klima Irena , Chen Lanpeng , Snaar-Jagalska Ewa B. , Flanagan Kenneth , van der Pluijm Gabri , Kloen Peter , Cecchini Marco G. , Kruithof-de Julio Marianna , Thalmann George N.
Published: April 2023

Genes downregulated in RNASeq.
Supplementary Table 1 from A First-in-Class TWIST1 Inhibitor with Activity in Oncogene-Driven Lung Cancer
Authors: Yochum Zachary A. , Cades Jessica , Mazzacurati Lucia , Neumann Neil M. , Khetarpal Susheel K. , Chatterjee Suman , Wang Hailun , Attar Myriam A. , Huang Eric H.-B. , Chatley Sarah N. , Nugent Katriana , Somasundaram Ashwin , Engh Johnathan A. , Ewald Andrew J. , Cho Yoon-Jae , Rudin Charles M. , Tran Phuoc T. , Burns Timothy F.
Published: April 2023

Supplementary Table 1
Supplementary Figures 1-7 from Therapeutic Targeting of CD146/MCAM Reduces Bone Metastasis in Prostate Cancer
Authors: Zoni Eugenio , Astrologo Letizia , Ng Charlotte K.Y. , Piscuoglio Salvatore , Melsen Janine , Grosjean Joël , Klima Irena , Chen Lanpeng , Snaar-Jagalska Ewa B. , Flanagan Kenneth , van der Pluijm Gabri , Kloen Peter , Cecchini Marco G. , Kruithof-de Julio Marianna , Thalmann George N.
Published: April 2023

S1. Cell Sorting Workflow. S2. Effect of MCAM knockdown on RNA levels. S3. Overview of invivo study. S4. GSEA and gProfile enrichment analysis and enrichment maps. S5. Overview of in vivo study with monoclonal antiMCAM antibody administration. S6. Overview of bone morphometric images and histology. S7. Overview of kidney and bone histology.
Supplementary Figure 1 from Mutational Landscape of Ovarian Adult Granulosa Cell Tumors from Whole Exome and Targeted TERT Promoter Sequencing
Authors: Alexiadis Maria , Rowley Simone M. , Chu Simon , Leung Dilys T.H. , Stewart Colin J.R. , Amarasinghe Kaushalya C. , Campbell Ian G. , Fuller Peter J.
Published: April 2023

S1. Total number of mutated genes identified within this study that are also mutated in the studies of Caburet et al [21], Zehir et al [22], Kandoth et al [23], Lawrence et al [24] and Nik-Zainal et al [25]. Genes mutated in this current study are also presented as a percentage.
Table s-2 from Molecular Effects of Stromal-Selective Targeting by uPAR-Retargeted Oncolytic Virus in Breast Cancer
Authors: Jing Yuqi , Chavez Valery , Ban Yuguang , Acquavella Nicolas , El-Ashry Doraya , Pronin Alexey , Chen Xi , Merchan Jaime R.
Published: April 2023

Differential expression for mouse associated genes at day 2
Table S-3 from Molecular Effects of Stromal-Selective Targeting by uPAR-Retargeted Oncolytic Virus in Breast Cancer
Authors: Jing Yuqi , Chavez Valery , Ban Yuguang , Acquavella Nicolas , El-Ashry Doraya , Pronin Alexey , Chen Xi , Merchan Jaime R.
Published: April 2023

Differential expression for mouse associated genes at day 5
Supplemental Tables and Figure Legends from Therapeutic Effect of Y-27632 on Tumorigenesis and Cisplatin-Induced Peripheral Sensory Loss through RhoA–NF-κB
Authors: Zhu Yi , Howard George A. , Pittman Keith , Boykin Christi , Herring Laura E. , Wilkerson Emily M. , Verbanac Kathryn , Lu Qun
Published: April 2023

SI Table I. General Experiment Schedule SI Table II. Weekly Experiment Schedule SI Table III. Information for primary antibodies SI Table IV. Predicted Functions of Dysregulated Proteins from Proteomic Analysis SI Figure 1. The effect of Y-27632 treatment on tumor cell line and tumor tissue. SI Figure 2. Different dosages of cisplatin induced different manifestations of peripheral neuropathy.
Supplementary Figure S4 from Targeting CREB Pathway Suppresses Small Cell Lung Cancer
Authors: Xia Yifeng , Zhan Cheng , Feng Mingxiang , Leblanc Mathias , Ke Eugene , Yeddula Narayana , Verma Inder M.
Published: April 2023

Supplementary Figure S4. NF-κB and CREB activity in human SCLC samples.
Supplementary Figure S3 from Targeting CREB Pathway Suppresses Small Cell Lung Cancer
Authors: Xia Yifeng , Zhan Cheng , Feng Mingxiang , Leblanc Mathias , Ke Eugene , Yeddula Narayana , Verma Inder M.
Published: April 2023

Supplementary Figure S3. Kras-induced but not Mycl1-induced transformation relies on NF-κB activity for survival.
Supplementary Figure S2 from Targeting CREB Pathway Suppresses Small Cell Lung Cancer
Authors: Xia Yifeng , Zhan Cheng , Feng Mingxiang , Leblanc Mathias , Ke Eugene , Yeddula Narayana , Verma Inder M.
Published: April 2023

Supplementary Figure S2. RNAseq analysis of normal lung, control tumors (luci) and IκBαM tumors.
Supplementary Figure S1 from Targeting CREB Pathway Suppresses Small Cell Lung Cancer
Authors: Xia Yifeng , Zhan Cheng , Feng Mingxiang , Leblanc Mathias , Ke Eugene , Yeddula Narayana , Verma Inder M.
Published: April 2023

Supplementary Figure S1. Characterizing the SCLC mouse model.