bluuebunny/crossref_metadata_2025 huggingface dataset:
A New Quinone Based Fluorescent Probe for High Sensitive and Selective Detection of Biothiols and Its Application in Living Cell Imaging
Authors: Liu Yanju , Li Manman , Wong Keith Man-Chung , Tong Yan , Yang Huaixia , Kong Jinming
Published: April 2019

In view of the vital role of biothiols in many physiological processes, the development of simple and efficient probe for the detection of biothiols is of great medical significance. In this work, we demonstrate the use of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ), which respond rapidly to biothiols especially to glutathione, as a new fluorescent probe for the selective detection and bioimaging of biothiols. This new fluorescent probe can distinguish glutathione from cysteine and homocysteine easily under physiological concentration and detect glutathione quickly within three minutes. This probe exhibits high selectivity to biothiols and the detection limit was determined to be 3.08 × 10−9 M for glutathione, 8.55 × 10−8 M for cysteine, and 2.17 × 10−9 M for homocysteine, respectively. The sensing mechanism was further explored by density functional theory (DFT) and nuclear magnetic resonance (NMR) experiment; results showed that the interaction forces between the probe and biothiols were electrostatic interaction. In addition, the probe has been successfully applied to the detection of biothiols in Eca9706 cells by fluorescence confocal imaging technology.
Characterization of HCC Mouse Models: Towards an Etiology-Oriented Subtyping Approach
Authors: Friemel Juliane , Frick Lukas , Unger Kristian , Egger Michele , Parrotta Rossella , Böge Yannick T. , Adili Arlind , Karin Michael , Luedde Tom , Heikenwalder Mathias , Weber Achim
Published: April 2019

Murine liver tumors often fail to recapitulate the complexity of human hepatocellular carcinoma (HCC), which might explain the difficulty to translate preclinical mouse studies into clinical science. The aim of this study was to evaluate a subtyping approach for murine liver cancer models with regard to etiology-defined categories of human HCC, comparing genomic changes, histomorphology, and IHC profiles. Sequencing and analysis of gene copy-number changes [by comparative genomic hybridization (CGH)] in comparison with etiology-dependent subsets of HCC patients of The Cancer Genome Atlas (TCGA) database were conducted using specimens (75 tumors) of five different HCC mouse models: diethylnitrosamine (DEN) treated wild-type C57BL/6 mice, c-Myc and AlbLTαβ transgenic mice as well as TAK1LPC-KO and Mcl-1Δhep mice. Digital microscopy was used for the assessment of morphology and IHC of liver cell markers (A6-CK7/19, glutamine synthetase) in mouse and n = 61 human liver tumors. Tumor CGH profiles of DEN-treated mice and c-Myc transgenic mice matched alcohol-induced HCC, including morphologic findings (abundant inclusion bodies, fatty change) in the DEN model. Tumors from AlbLTαβ transgenic mice and TAK1LPC-KO models revealed the highest overlap with NASH-HCC CGH profiles. Concordant morphology (steatosis, lymphocyte infiltration, intratumor heterogeneity) was found in AlbLTαβ murine livers. CGH profiles from the Mcl-1Δhep model displayed similarities with hepatitis-induced HCC and characteristic human-like phenotypes (fatty change, intertumor and intratumor heterogeneity).

Implications:

Our findings demonstrate that stratifying preclinical mouse models along etiology-oriented genotypes and human-like phenotypes is feasible. This closer resemblance of preclinical models is expected to better recapitulate HCC subgroups and thus increase their informative value.
Comorbidity of Vitamin A and Vitamin D Deficiency Exacerbates the Severity of Atopic Dermatitis in Children
Authors: Xiang Juan , Wang Hua , Li Tingyu
Published: April 2019

Background: Several studies have suggested that vitamin D (VD) deficiency (VDD) is associated with atopic dermatitis (AD). However, little is known about the relationship between AD and vitamin A (VA). The interaction between VA and VD on AD requires further study. Objective: We detected serum levels of VA and VD in children with AD to explore how VA deficiency (VAD) and VDD affect AD severity. Methods: We assessed the SCORing Atopic Dermatitis (SCORAD) index, total immunoglobin E levels and peripheral blood eosinophil counts. VA and VD levels were determined with high-performance liquid chromatography. Correlations among variables were investigated with Pearson’s correlation analysis. Results: The VD and VA levels were significantly lower in children with AD than in normal children (p < 0.001, p = 0.0423). Both VD and VA levels were negatively correlated with SCORAD scores. The SCORAD scores were significantly higher in AD patients with both VDD and VAD (co-deficiency) than in other AD patients. Significant inverse correlations were observed between peripheral blood eosinophil counts and serum VA and VD levels. Conclusions: VA and VD co-deficiency may exacerbate AD symptoms in children, but the specific mechanism underlying this relationship requires further study. These findings may indicate the need for studies evaluating the use of VD and VA as potential treatments for AD patients.
A 2-Year Observational Study in Patients Suffering from Idiopathic Pulmonary Fibrosis and Treated with Pirfenidone: A French Ancillary Study of PASSPORT
Authors: Jouneau Stéphane , Gamez Anne-Sophie , Traclet Julie , Nunes Hilario , Marchand-Adam Sylvain , Kessler Romain , Israël-Biet Dominique , Borie Raphael , Strombom Indiana , Scalori Astrid , Crestani Bruno , Valeyre Dominique , Cottin Vincent
Published: April 2019

Background: The European observational, prospective PASSPORT study evaluated the long-term safety of pirfenidone under real-world conditions in idiopathic pulmonary fibrosis (IPF), over up to 2 years following its initiation. Objectives: The FAS (French Ancillary Study) assessed the clinical outcomes of IPF patients participating in PASSPORT (n = 192). Methods: Efficacy data were collected retrospectively and prospectively. The primary efficacy endpoints were: change in percent predicted forced vital capacity (FVC) and change in the distance travelled during the 6-min walk test (6MWD). Results: The mean baseline FVC was 71.7% of predicted value. The mean absolute change in the percentage of predicted FVC was –2.4% and –3.8% at months 12 and 24. The mean change in 6MWD was 8.6 and 3.1 m at months 12 and 24, with a range of 23.4–51.7 m. Acute IPF exacerbation and pulmonary hypertension occurred in 20.0 and 8.4% of patients, respectively. The most common reasons for prematurely discontinuing PASSPORT were adverse drug reactions (ADRs) related to pirfenidone (31.3%), death (11.5%), and disease progression (10.9%). The median progression-free survival was 18.4 months (95% CI 12.9, not estimable). The median exposure was 16.3 months (0.5–28.5). The most frequently reported ADRs leading to pirfenidone discontinuation were decreased weight (4.2%), rash (4.2%), and photosensitivity reactions (3.1%). Conclusions: The efficacy data of FAS are consistent with the efficacy results of published phase III clinical trials in IPF. Approximately one third of IPF patients treated with pirfenidone in real-life settings were still under treatment 2 years after initiation. Safety data are consistent with the known safety profile of pirfenidone.
Colony-Forming Cell Assay Detecting the Co-Expression of JAK2V617F and BCR-ABL1 in the Same Clone: A Case Report
Authors: Tirrò Elena , Stella Stefania , Massimino Michele , Zammit Valentina , Pennisi Maria Stella , Vitale Silvia Rita , Romano Chiara , Di Gregorio Sandra , Puma Adriana , Di Raimondo Francesco , Stagno Fabio , Manzella Livia
Published: April 2019

BCR-ABL1-negative myeloproliferative disorders and chronic myeloid leukaemia are haematologic malignancies characterised by single and mutually exclusive genetic alterations. Nevertheless, several patients co-expressing the JAK2V617F mutation and the BCR-ABL1 transcript have been described in the literature. We report the case of a 61-year-old male who presented with an essential thrombocythaemia phenotype and had a subsequent diagnosis of chronic phase chronic myeloid leukaemia. Colony-forming assays demonstrated the coexistence of 2 different haematopoietic clones: one was positive for the JAK2V617F mutation and the other co-expressed both JAK2V617F and the BCR-ABL1 fusion gene. No colonies displayed the BCR-ABL1 transcript alone. These findings indicate that the JAK2V617F mutation was the founding genetic alteration of the disease, followed by the acquisition of the BCR-ABL1 chimeric oncogene. Our data support the hypothesis that a heterozygous JAK2V617F clone may have favoured the bi-clonal nature of this myeloproliferative disorder, generating clones harbouring a second transforming genetic event.
Open-Label Clinical Trials of Oral Pulse Dexamethasone for Adults with Idiopathic Nephrotic Syndrome
Authors: Cho Monique E. , Branton Mary H. , Smith David A. , Bartlett Linda , Howard Lilian , Reynolds James C. , Rosenstein Donald , Sethi Sanjeev , Nava M. Berenice , Barisoni Laura , Fervenza Fernando C. , Kopp Jeffrey B.
Published: April 2019

Background: In adults with primary focal segmental glomerulosclerosis (FSGS), daily prednisone may induce complete remissions (CR) and partial remissions (PR), but relapses are frequent and adverse events are common. Methods: We carried out 2 open-label, uncontrolled trials to explore the efficacy and tolerability of pulse oral dexamethasone as an alternative to daily prednisone. We enrolled adult patients with proteinuria > 3.5 g/day despite the use of renin-angiotensin-aldosterone blockade. In the first trial, we enrolled 14 subjects with FSGS and administered 4 dexamethasone doses (25 mg/m2) daily for 4 days, repeated every 28 days over 32 weeks. The second trial involved a more intensive regimen. Eight subjects received 4 dexamethasone doses of 50 mg/m2 every 4 weeks for 12 weeks, followed by 4 doses of 25 mg/m2 every 4 weeks for 36 weeks; subjects were randomized to 2 doses every 2 weeks or 4 doses every 4 weeks. Results: In the first trial, we enrolled 13 subjects with FSGS and 1 with minimal change disease and found a combined CR and PR rate of 36%. In the second trial, we enrolled 8 subjects. The combined CR and PR rate was 29%. Analysis combining both trials showed a combined CR and PR rate of 33%. Adverse events were observed in 32% of subjects, with mood symptoms being most common. There were no serious adverse events related to the study. Conclusion: We conclude that high dose oral dexamethasone is well tolerated by adults with idiopathic nephrotic syndrome and may have some efficacy.
Born Preterm: A Public Health Issue
Authors: Pinto Filomena , Fernandes Eduardo , Virella Daniel , Abrantes Alexandre , Neto Maria Teresa
Published: April 2019

Background: Prematurity accounts for about 10.6% of neonates worldwide and tends to increase as does survival from lower gestational ages. Summary: The importance of preterm birth in public health stems from its link to infant and under-5 mortality, morbidity, and its economic impact. In both the short and long term, preterm birth consequences are inversely related with gestational age and carry a higher risk of mortality and morbidity with neurodevelopmental, sensorial, cognitive and physical health disturbances. Individuals needing lifelong support pose challenges to the responsiveness of health services and community systems. Public health can be decisive in prematurity prevention, providing data to policy-makers and reducing modifiable risk factors. This paper focuses on the long-term consequences of preterm birth and possible public health measures to tackle them. Key Messages: Addressing social determinants of health can have the highest impact on prematurity outcomes.
Laparoscopic Myomectomy with Temporary Bilateral Uterine Artery and Utero-Ovarian Vessels Occlusion Compared with Traditional Surgery for Uterine Fibroids: Blood Loss and Recurrence
Authors: Jin Lanying , Ji Limei , Shao Mingjun , Hu Min
Published: April 2019

Aim: To determine the optimal hemostatic technique for laparoscopic myomectomy (LM) by comparing temporary uterine artery blockage alone or combined with blockage of the utero-ovarian vessels. Patients: Women with symptomatic uterine myoma attending the Department of Obstetrics and Gynecology in Jinhua Municipal Central Hospital. Method: A total of 200 patients with symptomatic uterine fibroids were randomly divided into Group A (n = 65), Group B (n = 67) and Group C (n = 68). At the beginning of the procedure, 6 U of vasopressin was injected into the myometrium of all women. LM was performed in Group A; temporary bilateral uterine artery occlusion and myomectomy were performed in Group B and temporary bilateral uterine artery and utero-ovarian vessel occlusion was performed in Group C. We then evaluated operative time, perioperative bleeding, follow-up relief of menorrhagia, and the recurrence of fibroids. Results: General characteristics of the patients were similar across all 3 groups. All patients underwent successful laparoscopic operation and none of the cases needed to be converted to laparotomy; there were no intraoperative complications. There was no significant difference in the operative time between groups (p = 0.332 and p = 0.346 for single-myoma and multiple-myoma respectively), and for both single and multiple-myoma groups, the blood loss was significantly lower in Group C than Groups A and B (p < 0.001). There were no differences in the recurrence rate and menorrhagia symptom relief outcomes when ­compared across the 3 groups at the 30-month follow-up (p = 0.953 and p = 0.841, respectively). At final follow-up, the pregnancy rate of the sexually active patients without contraception was not statistically significant (p = 0.958). The fertility index of anti-Mullerian hormone showed no statistical difference between groups preoperatively or at 2 days, 3 months, 6 months, and 1 year postoperatively (p = 0.998, p = 0.965, p = 0.999, p = 0.994 and p = 0.993, respectively). Conclusion: LM with temporary bilateral uterine artery and utero-ovarian vessels occlusion has the advantages of less intraoperative bleeding compared with LM and laparoscopic transient uterine artery ligation and does not increase the mean operative time.
Application of a Self-Made Equipment for Patient Positioning during Percutaneous Nephroscopy in the Oblique-Supine Position
Authors: Xia Qiang , Zhao Zhenhua , Li Chengbo , Hao Xiaoqiang , Dun Wenchao
Published: April 2019

Background: The oblique-supine position for percutaneous nephrolithotomy (PCNL) has advantages, but the position fixation methods are inadequate. This study aimed to analyze the PCNL outcomes using a patented self-made frame for oblique-supine position. Methods: This was a prospective study of patients scheduled to undergo PCNL at 2 hospitals in China between November 2009 and December 2016. The patients underwent PCNL in the oblique-supine position using the self-made position frame (n = 94). Operative time, stone clearance rate, intraoperative average systolic pressure, intraoperative average heart rate, intraoperative average airway pressure, intraoperative average intrapelvic pressure, and complications were observed. Results: The patients were 45.3 ± 19.7 years old and 71% were male. Stones were of the size 2.5 ± 1.1 cm. The operative time was 95.6 min and the stone clearance rate was 81.9%. Intraoperative systolic blood pressure was 15.13 ± 1.68 kPa. Intraoperative airway pressure was 15.5 ± 2.3 cm H2O. Postoperative fever was observed in 3.2% of the patients. None had organ injury. Postoperative stay was 4.8 ± 0.6 days. The nephrostomy tube was routinely removed on the 5th day after surgery and the patients were discharged on the following day. Conclusion: The self-made surgical position frame met the position requirements for the oblique-supine PCNL operation. This surgical position frame deserves clinical application and promotion.
Large Cell Neuroendocrine Carcinoma of the Prostate: A Systematic Review and Pooled Analysis
Authors: Tu Xiang , Chang Tiancong , Nie Ling , Qiu Shi , Xu He , Huang Yin , Bao Yige , Liu Zhenhua , Yang Lu , Wei Qiang
Published: April 2019

Background: Large cell neuroendocrine carcinoma (LCNEC) of the prostate is an extremely rare entity, and the clinicopathological course, potential effective treatment, and prognosis are yet to be elucidated. Materials and Methods: A systematic search in Pubmed, Embase, and Ovid from inception to January 2019 was conducted. We reviewed each individual case of prostatic LCNEC and summarized specific features and outcomes for this rare pathologic entity. Results: Thirteen studies with a total of 20 patients (mean age: 70.3, range 43–87) were included in our review. Seventeen patients harbored primary LCNEC of the prostate, of which 9 patients were diagnosed with de novo carcinoma, and 8 patients were with a history of prostatic adenocarcinoma treated with hormonal therapy (mean duration: 2.9 years, range 2–5). The other 3 patients were diagnosed with metastatic LCNEC originating from lung (2 cases) and bladder (1 case). All patients met the diagnostic criteria of the typical morphological features as well as immunohistochemical staining results. Nearly all primary de novo LCNEC of the prostate were at a late stage at initial diagnosis. The pattern of distant metastasis resembled that of prostatic adenocarcinoma with the most common sites as bone spread (8/16, 50%). Most patients received systematic chemotherapy after diagnosis; however, the prognosis remained poor and patients deteriorated rapidly but with exception. Three reported cases in the context of de novo LCNEC admixed with prostatic adenocarcinoma kept sustained response to androgen deprivation therapy (ADT) and achieved obviously better survival outcomes compared with other patients. Conclusions: LCNEC of the prostate is a rare entity that mostly occurs after long-standing hormonal therapy of prostatic adenocarcinoma. The prognosis was universally poor irrespective of the systematic chemotherapy. However, patients of de novo tumor mixed with prostatic adenocarcinoma may respond to ADT and harbor a better outcome than those of pure de novo or post-ADT LCNEC of the prostate.
Evaluation of a commercial liquid-chromatography high-resolution
mass-spectrometry method for the determination of hepcidin-25
Authors: Enko Dietmar , Zelzer Sieglinde , Fauler Günter , Herrmann Markus
Published: April 2019

Introduction: Reliable determination of hepcidin-25, a key regulator of iron metabolism, is important. This study aimed at evaluating the performance of the Hepcidin-25 Liquid Chromatography-Tandem Mass-Spectrometry (LC-MS/MS) Kit (Immundiagnostik AG, Bensheim, Germany) for quantification of the hepcidin-25 protein.
Materials and methods: Precision, accuracy, linearity, and preanalytical requirements of the liquid-chromatography high-resolution massspectrometry (LC-HR-MS) method were evaluated. The imprecision and bias acceptance criteria were defined ≤ 15%. We investigated sample stability at room temperature (RT) and after repeated freeze and thaw cycles. Additionally, we assessed serum hepcidin-25 concentrations of 165 healthy
adults referred for a medical check-up.
Results: The hepcidin-25 LC-MS/MS assay was linear over the concentration range of 3 – 200 ng/mL. Within- and between-run precision ranged between 1.9 – 8.6% and 5.1 – 12.4%, respectively. The mean bias of the low and high control material was - 2.7% and 2.1%, respectively. At RT, serum samples were stable for 3 h (mean bias + 0.3%). After two and three freeze and thaw cycles, hepcidin-25 concentrations showed a bias of +8.0 and + 20%, respectively. Of 165 healthy adults, 109 females had a significantly lower median of 8.42 (range: 1.00 – 60.10) ng/mL compared to 56 males with 15.76 (range: 1.50 – 60.50) ng/mL (P = 0.002).
Conclusions: The hepcidin-25 LC-MS/MS kit shows a broad analytical range and meets the imprecision and bias acceptance criteria of ≤ 15%. Serum samples can be stored at RT for 3 h and resist up to two freeze and thaw cycles.
A taxonomic review of the grassland leafhopper genus Aconurella Ribaut (Hemiptera: Cicadellidae: Deltocephalinae: Chiasmini) from China with the description of two new species
Authors: DUAN YANI , ZHANG YALIN
Published: April 2019

Six species of the genus Aconurella Ribaut from China are reviewed including two new records and two new species; de-scriptions and illustrations of these species are provided. Two new species A. furcata sp. n. and A. paradiplachnis sp. n.are described. A key to males of the Chinese species in the genus is also given. A. orientalis is considered a junior synonym of A. prolixa syn. n. and A. solana is considered a junior synonym of A. montana syn. n.
New species and additional evidence of aphid parasitoids (Hymenoptera: Braconidae: Aphidiinae) from India
Authors: RAKHSHANI EHSAN , BARAHOEI HOSSEIN , AHMED ZUBAIR , TOMANOVIĆ ŽELJKO , JANKOVIĆ MARINA , PETROVIĆ ANDJELJKO , BODLAH IMRAN , STARÝ PETR
Published: April 2019

A survey was carried out on Aphidiinae of India. Fifteen species belonging to nine genera were identified, of which Aphid-ius bifurcatus Rakhshani & Tomanović and Ephedrus longiarticulatus Rakhshani & Tomanović are newly described andillustrated. Aphidius funebris Mackauer was recorded for the first time from India. A brief taxonomic note with regard to the morphological variability of diagnostic characters as well as comments on geographical distribution are presented.
Revision of the Malagasy genus Lechius Iwan, 1995 (Coleoptera: Tenebrionidae: Pedinini)
Authors: IWAN DARIUSZ , KAMIŃSKI MARCIN JAN
Published: April 2019

The taxonomic concept of the genus Lechius Iwan, 1995 and the hypotheses of all its species, are tested basing on newlyavailable material from Madagascar. Comparative analysis showed that the male and female genitalia most apparently re-flect the evolutionary trends within this genus. Two new Lechius species are described: L. aalbui sp. nov. and Lechiuslongiclavis sp. nov. A distributional map is presented with complete faunistic data on the genus. An identification key is provided to all known species of Lechius.
Six new species of Nazeris Fauvel (Coleoptera, Staphylinidae, Paederinae) from Guangxi, South China
Authors: HU JIA-YAO , LI LI-ZHEN , ZHAO MEI-JUN
Published: April 2019

Six new species of Nazeris Fauvel collected from Dayao Mountain, Guangxi Province, are described and illustrated: N.dayaoensis Hu & Li, sp. n., N. luoi Hu & Li, sp. n., N. tani Hu & Li, sp. n., N. qini Hu & Li, sp. n., N. megalobus Hu &Li, sp. n. and N. grandis Hu & Li, sp. n. An identification key to the Nazeris species from Guangxi and its adjacent areas is provided.
Two new species of Atlantocuma (Crustacea: Cumacea), and a new genus and species from Japan, Northwest Pacific, with observations on the degeneration of mouthparts in ovigerous females
Authors: AKIYAMA TADASHI
Published: April 2019

Two species of the cumacean genus Atlantocuma from the southern coast of Honshu, Japan, 781–861 m depth, A. gamoisp. nov. and A. ojii sp. nov., and Pseudopicrocuma japonicum gen et sp. nov. from Nansei Islands, 566–1769 m depth,are described. Atlantocuma gamoi is characterized by (1) carapace elevated in preparatory and ovigerous female, (2)antero-lateral angle of carapace with 3 teeth in females, and (3) pseudorostrum of carapace of adult males truncate,anterolateral angle without teeth. Atlantocuma ojii is characterized by (1) carapace not elevated in preparatory females,but elevated in ovigerous females, (2) inferior margin of carapace in ovigerous female serrated for entire length, (3)pseudorostrum of carapace in adult males truncate, (4) uropod exopod with 1–2 spiniform setae on inner margin, exceptfor subterminal one. The new genus Pseudopicrocuma, which is similar to Picrocuma from shallow waters of easternAustralia, is characterized by (1) well-developed exopods present on maxilliped 3 and pereopods 1–3 in both sexes, (2)antenna 1 of adult males with many aesthetascs-like sensory setae on peduncle articles 2 and 3, (3) male antenna 2 ofclasping form, and (4) uropod slender, peduncle shorter than rami. Pseudopicrocuma shows affinity to Atlantocuma exceptfor (1) arrangement of well-developed exopods on pereopods, (2) male antenna 2 flagellum of clasping form, and (3)uropod peduncle shorter than rami. In addition, P. japonicum and the new Japanese Atlantocuma species are characterizedby a similar trend in degeneration of mouthparts (mandibles – maxillipeds 2) in ovigerous females, suggesting a ratherclose relationship of these genera with quite different arrangements of exopods on pereopods. These 2 genera are currentlyplaced in Nannastacidae. Other possible relatives of Pseudopicrocuma are Spilocuma (Bodotriidae) and Claudicuma (Nannastacidae).
Anterastes davrazensis sp. n. (Orthoptera, Tettigoniidae): morphology, song and 16S rDNA phylogeny
Authors: KAYA SARP , CHOBANOV DRAGAN , ÇIPLAK BATTAL
Published: April 2019

The new species Anterastes davrazensis sp. n. (Orthoptera, Tettigoniidae) is described from south-eastern Turkey. Description, diagnosis and relationships of the new species were studied utilizing morphology, male calling songs and 16S rDNA sequence data from all species in the genus. Morphology and song syllable structure indicate A. davrazensis sp. n. is related to A. uludaghensis. Phylogenetic analyses based on representative haplotypes of 16S rDNA, using Sureyaella bella, Parapholidoptera distincta and Bolua turkiyae as outgroups, also suggested strong support to the relationship of these two species. A. davrazensis sp. n. differs from its closest relative A. uludaghensis by the higher number of stridulatory pegs and the song, consisting of irregular syllable groups.
Description of the male of Culicoides (Hoffmania) baniwa Felippe-Bauer of the hylas species group (Diptera: Ceratopogonidae)
Authors: CASTELLÓN ELOY GUILLERMO , PESSOA FELIPE ARLEY COSTA , SPINELLI GUSTAVO , FELIPPE-BAUER MARIA LUIZA
Published: April 2019

Borkent (2012) recognized 44 Neotropical species of Culicoides Latreille in the subgenus Hoffmania Fox. Of these, 33 belong to the C. guttatus species group and 11 to the C. hylas species group. One species in the latter group, Culicoides baniwa Felippe-Bauer, was recently described based on a female specimen collected in São Gabriel da Cachoeira, Amazonas, Brazil (Felippe-Bauer et al., 2009). The authors also include a key and a synopsis of the species of this group, which includes seven species inhabiting the Brazilian Amazon Region.
A review of characters useful in delineating ampharetid genera (Polychaeta)
Authors: SALAZAR-VALLEJO SERGIO I. , HUTCHINGS PAT
Published: April 2019

The polychaete family Ampharetidae currently contains many monotypic genera. The usefulness of various characters is assessed in order to provide a more coherent framework on which to base the classification of the family.
Two new species of the genus Eubasilissa Martynov (Trichoptera: Phryganeidae) from the Indian Himalaya
Authors: PAREY SAJAD H. , SAINI MALKIAT S.
Published: April 2019

Two new species of the genus Eubasilissa Martynov are described and illustrated from the Indian Himalaya, namelyEubasilissa sikkimensis sp. nov. from Lachung (Sikkim) that appears close to Eubasilissa maclachlani (White, 1862) andEubasilissa schmidi sp. nov. from Bhaderwah (Jammu & Kashmir) that resembles Eubasilissa avalokhita Schmid, 1962.The female of Eubasilissa asiatica (Betten, 1909) is described and illustrated for the first time from Gurez valley (Jammu & Kashmir). With this addition of 2 new species, the genus Eubasilissa is now represented by 9 valid species from India.
Checklist of treehoppers of Panama (Hemiptera: Membracidae) with a list of checklists and keys to the Nearctic and Neotropical fauna
Authors: FLYNN DAWN J.
Published: April 2019

A checklist of treehoppers (Hemiptera: Membracidae) of Panama is provided with known province distribution data. The worldcatalogue of Membracoidea, through 1996, lists 68 genera, 162 species, and 1 subspecies from Panama (McKamey, 1998).New research in Panama has documented range extensions for 29 genera, 107 species, and 1 subspecies previously unknownfrom Panama. With these adjustments and additions, the total treehopper fauna from Panama includes 97 genera, 269 species, and 2 subspecies. Tables listing published checklists and keys for Nearctic and Neotropical treehoppers are presented.
New picobiin mites (Acari: Syringophilidae: Picobiinae) associated with woodcreeper birds (Passeriformes: Dendrocolaptidae)
Authors: SKORACKI MACIEJ , SOLARCZYK PIOTR
Published: April 2019

Two new species belonging to the genus Rafapicobia Skoracki, 2011 (Syringophilidae: Picobiinae) collected from birdsof the family Dendrocolaptidae are described: 1) Rafapicobia dendrocolaptesi sp. nov. from Dendrocolaptes platyrostrisSpix (type host) in Paraguay and from D. picumnus Lichtenstein in Argentina; 2) Rafapicobia lepidocolaptesi sp. nov.from Lepidocolaptes affinis (Lafresnaye) (type host) in Ecuador and Venezuela and from L. souleyetii (Des Murs) in Colombia. Syringophilid mites are recorded from woodcreepers for the first time.
Two new species of hermit crabs of the genus Areopaguristes Rahayu & McLaughlin, 2010 (Crustacea: Anomura: Paguroidea: Diogenidae) from the eastern tropical Pacific
Authors: AYÓN-PARENTE MANUEL , HENDRICKX MICHEL E.
Published: April 2019

The genus Areopaguristes Rahayu & McLaughlin, 2010 is represented in the eastern Pacific by a single species, A.mclaughlinae (Ayón-Parente & Hendrickx, 2006). Based on material recently collected in the Gulf of California, Mexico,and held in museum collections, two new species of this genus are described. Areopaguristes lemaitrei sp. nov. and A.waldoschmitti sp. nov. Both have the typical 12 gills of the genus. In addition to its color pattern, A. lemaitrei sp. nov. isdistinguished by the presence of corneous-tipped spines on palm and fingers, a broadly rounded rostrum shorter than lat-eral projections, and by the shape of the external lobe of the first pleopod. Areopaguristes waldoschmitti sp. nov. also fea-tures a distinctive color pattern, a less spinous armature of chelipeds, antennular peduncles proporcionally longer andantennal acicle shorter, a deep median cleft on the posterior margin of telson, and the distal margin of the inferior lamella of the first male pleopod is unarmed; this last character separates A. waldoschmtti sp. nov. from all its congeners.
An Annotated Catalog of the Iranian Lygaeoidea (excluding Berytidae and Piesmatidae) (Hemiptera: Heteroptera: Pentatomomorpha)
Authors: GHAHARI HASSAN , MOULET PIERRE
Published: April 2019

The Iranian fauna of the Lygaeoidea (excluding Berytidae and Piesmatidae) is summarized in this paper. In total, 9families, 7 subfamilies, 87 genera and subgenera, and 238 species and subspecies are listed from Iran. One species, Dieuches armatipes (Walker, 1872), is newly recorded from Iran.
Brachysomus (Hippomias) samos sp. n. from Greece—first island endemism in the genus (Coleoptera: Curculionidae: Entiminae)
Authors: YUNAKOV NIKOLAI , GERMANN CHRISTOPH
Published: April 2019

Brachysomus (Hippomias) samos sp. n. is described from the Oros Ambelos mountains on Samos Island (Greece). Thehygrophilous and detritivorous new species is endemic to a very restricted area. Brachysomus samos is close to B. pelexYunakov, 2006, B. moczarskii Penecke, 1924 and B. armatus Yunakov, 2006 based on characteristics of the median lobeof the aedeagus, and on the conspicuously long apodemes. Brachysomus samos furthermore strongly resembles B. armatus and B. curvimanus Yunakov, 2006 in the characteristic shape of the head capsule and epifrons.
A key to the Neotropical species of the Enicospilus ramidulus species-group (Hymenoptera: Ichneumonidae: Ophioninae), with the description of a new Brazilian species
Authors: LIMA ALESSANDRO RODRIGUES , JACOBI CLAUDIA MARIA , KUMAGAI ALICE FUMI
Published: April 2019

A key to the Neotropical species of the Enicospilus ramidulus species-group is provided, with the exception of GalápagosIslands species. A total of 22 specimens of E. purgatus (Say) were examined and its known distribution (Southern Brazil)extended to the states of Bahia and Amazonas, in Northeastern and Northern Brazil, respectively. A new species, Enicospilus diae Lima & Kumagai sp. n., is described from Southeastern Brazil.
Fur mites of the genus Schizocarpus Trouessart (Acari: Chirodiscidae) from the Eurasian beaver Castor fiber tuvinicus Lavrov (Rodentia: Castoridae) in the Azas River (Tuva Republic, Russia)
Authors: BOCHKOV ANDRE V. , SAVELJEV ALEXANDER P.
Published: April 2019

Sixteen species of the genus Schizocarpus Trouessart, 1896 (Acari: Chirodiscidae) are recorded from six live individualsof the Eurasian beaver Castor fiber tuvinicus Lavrov (Rodentia: Castoridae) captured at the Azas River (Tuva, Russia).Six species are described as new: Schizocarpus azasicus sp. nov., S. daberti sp. nov., S. heideckei sp. nov., S. lavrovi sp.nov., S. unzhakovi sp. nov., and S. tuvinicus sp. nov. Ten previously described species are as follows: S. brachyurus(Dubinina, 1964), S. grandis (Dubinina, 1964), S. fedjushini (Dubinina, 1964), S. gozdziewskii Bochkov et al., 2012, S.insignis Fain and Lukoschus, 1985, S. modestus Fain and Lukoschus, 1985, S. pusillus Fain and Lukoschus, 1985, S.radiatus Fain and Lukoschus, 1985, S. subornatus Fain and Lukoschus, 1985, and S. zurowskii Bochkov et al., 2012.Schizocarpus intercalatus Fain and Lukoschus, 1985 syn. nov. and S. parabrachyurus Fain and Lukoschus, 1985 syn. nov.are considered as junior synonyms of S. brachyurus; S. ventricosus Fain and Lukoschus, 1985 syn. nov. is considered as a junior synonym of S. latus (Dubinina, 1964).
A new species of rainfrog of the genus Diasporus (Anura: Eleutherodactylidae) from Serranía de Tabasará, Panama
Authors: BATISTA ABEL , PONCE MARCOS , HERTZ ANDREAS
Published: April 2019

A new frog species of the genus Diasporus is described from Llano Tugrí, Corregimiento de Peña Blanca, Distrito de Müna,Comarca Ngöbe-Buglé, Serranía de Tabasará, west-central Panama, around 1700 m a.s.l. The new species differs from all othermembers of the genus by a combination of morphological characters, in particular, its large size, its dorsal skin texture and itsbright coloration. This species is the largest species in the genus Diasporus; it is an inhabitant of cloud forest, living amongmosses and bromeliads. All specimens were found between the understory (≈ 1–2 m) and the mid-canopy (≈ 2–10 m). The callof this species consists of single, short notes that are reminiscent of a “whistle” and range from 2.0 to 2.7 kHz. Herein we pres-ent, besides morphological data used to describe the new species, the description of the male mating call, a distribution map, and brief ecological notes.
A taxonomic revision of the Colombian species of Urosigalphus Ashmead (Hymenoptera: Braconidae)
Authors: _ ARIAS-PENNA , CAROLINA DIANA , WHITFIELD JAMES B.
Published: April 2019

The Colombian species of parasitoid wasp Urosigalphus are revised for the first time, based on specimens deposited inmuseums. Almost all the material was collected by Malaise trap in the understory stratum of the seasonally flooded forest(varzea), submontane forest, and lowland forest, located in protected areas. 23 new species are described and illustrated:U. aliuslongitudinis Arias-Penna, n. sp., U. amandae Arias-Penna, n. sp., U. carinaverticis Arias-Penna, n. sp., U.cavusscuti Arias-Penna, n. sp., U. colombiensis Arias-Penna, n. sp., U. colordissimilis Arias-Penna, n. sp., U.faciescarinae Arias-Penna, n. sp., U. fimbriaeplanae Arias-Penna, n. sp., U. frequens Arias-Penna, n. sp., U. inaequalisArias-Penna, n. sp., U. macarenaensis Arias-Penna, n. sp., U. margo Arias-Penna, n. sp., U. metanotuminsignum Arias-Penna, n. sp., U. monticola Arias-Penna, n. sp., U. notauliremoti Arias-Penna, n. sp., U. ocellivicini Arias-Penna, n. sp.,U. ordoincompositus Arias-Penna, n. sp., U. sharkeyi Arias-Penna, n. sp., U. singularis Arias-Penna, n. sp., U. taniaeArias-Penna, n. sp., U. tredecimantennae Arias-Penna, n. sp., U. triacarinae Arias-Penna, n. sp., and U. whitfieldi AriasPenna, n. sp. An updated key to the known South American species is presented.
Two new species of the apterous Carventinae genus Comorocoris Heiss, 1985 from Madagascar (Hemiptera: Heteroptera: Aradidae)
Authors: HEISS ERNST , BAŇAŘ PETR , RAHANITRINIAINA LALAO SAHONDRA
Published: April 2019

The monobasic genus Comorocoris Heiss, 1985 was erected for the peculiar apterous species C. testudiformis fromMoheli Island [= Mwali] of the Comoro Archipelago. Recent forest litter sifting in Madagascar unexpectedly brought to light two new species belonging to this genus which are described and illustrated. A key to the three species is given.
Plant bugs of the tribe Bothriomirini (Hemiptera: Heteroptera: Miridae: Cylapinae) from the Oriental Region: descriptions of eight new species and keys to Oriental genera and species of Bothriomiris Kirkaldy, Dashymenia Poppius, and Dashymeniella Poppius
Authors: WOLSKI ANDRZEJ , GORCZYCA JACEK
Published: April 2019

Eight new species of the tribe Bothriomirini are described from the Oriental Region, namely Dashymenia cognata sp. nov., Dashymenia colubrina sp. nov., Dashymenia conspersa sp. nov., Dashymenia tenmalai sp. nov., Dashymenia webbi sp. nov., Dashymeniella spatulatiformis sp. nov., Dashymeniella ulu sp. nov., and Dashymeniella viklundi sp. nov. Five species are redescribed: Bothriomiris dissimulans (Walker), B. lugubris Poppius, B. testaceus Distant, Dashymenia croesus (Distant), and Dashymenia remus (Distant). Illustrations of the male genitalia, a color dorsal habitus photograph of the adult of most species, scanning electron micrographs of selected structures of Bothriomiris dissimulans, Dashymenia tenmalai, Dashymeniella spatulatiformis, and Dashymeniella ulu are given. An identification key to the Oriental genera and keys to species of the genera Bothriomiris, Dashymenia, and Dashymeniella are provided.
The larva of the genus Paracordulia Martin, 1907 (Odonata: Corduliidae s.s.) and a generic key to the larvae of Corduliidae s.l. occuring in South America
Authors: FLECK GÜNTHER , NEISS ULISSES G.
Published: April 2019

The ultimate stadium of a larva of the genus Paracordulia Martin, 1907 is described and illustrated for the first time. Itrepresents the last New World corduliid larva unknown at the generic level. The reared female differs slightly from otherknown female specimens, and thus no species name can be assigned to it. A key to the South American genera of corduliid larvae is given.
The South American genus Lagideus Konow (Hymenoptera: Pergidae: Syzygoniinae), a Supplement
Authors: SMITH DAVID R.
Published: April 2019

Six new species of the Neotropical pergid genus Lagideus are described and illustrated: Lagideus boyaca, L. magdalena, L. schmidti, and L. flavus from Colombia and L. tapanti, and L. isidro from Costa Rica. Lagideus romius Smith is newly recorded from Colombia and the female lancet is illustrated. Females are described for the first time for Lagideus longicus Smith from Costa Rica and L. albitarsis Malaise from southeastern Brazil, Uruguay, and Argentina.
Review of Goniozus Förster, 1856 (Hymenoptera: Bethylidae) of Korea, with descriptions of two new species
Authors: LIM JONGOK , LEE SEUNGHWAN
Published: April 2019

Five species of Goniozus are recognized in Korea. Goniozus koreanus Lim, sp. nov. and G. mesolevis Lim, sp. nov. are described and figured; G. akitsushimanus Terayama, 2006 and G. yoshikawai Terayama, 2006 are newly recorded from Korea. Goniozus maurus Marshall, 1905 is excluded from Korean fauna. A key to the Korean species in females is provided.
Remarks on the genus Homogryllacris Liu, 2007 (Orthoptera: Gryllacrididae: Gryllacridinae)
Authors: SHI FU-MING , GUO LI-YING , BIAN XUN
Published: April 2019

Four new species of the genus Homogryllacris Liu, 2007 are described, H. anelytra sp. nov., H. ascenda sp. nov., H. brevispina sp. nov. and H. yunnana sp. nov. A key to the species and the distributional data of the genus are provided. The all specimens recorded here are deposited in the Museum of Hebei University.
Revision of the genus Sinopoda Jäger, 1999 in Laos with discovery of the first eyeless huntsman spider species (Sparassidae: Heteropodinae)
Authors: JÄGER PETER
Published: April 2019

The genus Sinopoda Jäger, 1999 is recorded for the first time in Laos. Nine new species are described: Sinopoda steineri spec. nov. (female; Luang Nam Tha), S. tham spec. nov. (male, female; Oudomxai), S. sitkao spec. nov. (female; Luang Prabang), S. taa spec. nov. (female; Luang Prabang), S. suang spec. nov. (female; Huaphan), S. peet spec. nov. (female; Huaphan), S. guap spec. nov. (female; Khammuan), S. soong spec. nov. (female; Khammuan), S. scurion spec. nov. (female; Khammuan). All species have been collected from caves. Sinopoda scurion spec. nov. represents the first record of an eyeless huntsman spider, S. guap spec. nov. exhibits only small lenses of six eyes (AME lacking), S. soong spec. nov. has only two small eye lenses. Four immature individuals (Sinopoda sp. indet. A–D) exhibited a reduced size or number of eyes, they are listed including their localities although they could not be identified to species level.
The state of the art of Chromadoridae (Nematoda, Chromadorida): a historical review, diagnoses and comments about valid and dubious genera and a list of valid species
Authors: VENEKEY VIRAG , GHELLER PAULA F. , KANDRATAVICIUS NOELIA , CUNHA BEATRIZ PEREIRA , VILAS-BOAS ANA CAROLINA , FONSECA GUSTAVO , MARIA TATIANA F.
Published: April 2019

Chromadoridae is a widespread family of mostly free-living marine nematodes. This systematic review provides for each genus: a historical background, an updated diagnosis and a list of species. Our review recognizes 37 valid genera, 395 valid species, 57 descriptions without enough morphological information for accurate identification (species inquirenda) and 10 species incerta sedis. We also recognize 21 species as nomena nuda. Additionally, polytomous keys were constructed for the subfamilies and for the genera of the three major subfamilies (Chromadorinae, Euchromadorinae and Hypodontolaiminae) using the most important diagnostic characters. A phylogenetic analysis based on rDNA sequences of species available in the GenBank was also conducted. Phylogenetic trees based on the 18S and 28S rDNA confirmed the classification into three subfamilies (Spilipherinae, Hypodontolaiminae and Chromadorinae), despite the absence of defined synapomorphies. Phylogenetic relationships at lower taxonomic level are problematic given the large number of sequences not identified to species level.
A Novel Modeling of Quantum Dot Sensitized Solar Cells
Authors: Gangadhar Lekshmi , Praseetha P. K.
Published: April 2019

The electrical properties of quantum dot sensitized solar cells (QDSSC) under illumination and dark conditions are investigated and the measurements obtained on the cells are compared with theoretical calculations. Curve fitting are solved with the help of non-linear curve least squares
solver in MATLAB. The parameter matrix P was then fitted using the solver to minimize the mean square of deviation between the experimental and fitted data. Thus obtained parameters are used for modeling the solar cell in SIMULINK environment. This model is a phenomenological model to fit
I–V characteristics of real cells.
Qualitative Analysis for Improving Prediction Accuracy in Parkinson's Disease Detection Using Hybrid Technique
Authors: Geeitha S. , Thangamani M.
Published: April 2019

A PSO based SVM method has been implemented in diagnosing Parkinson's disease. This hybrid method produces parameter optimization and it helps to predict the gene expression pattern of the patient affected from Parkinson's disease. Implementing a computational tool on the PD data set
alleviates the symptoms to predict accurately the occurrence of the disease. In data classification, there may arise some incomplete or missing data during pre-processing in the probabilistic model. In order to overcome this, an Expectation Maximization (EM) algorithm is implemented. The proposed
Particle Swarm Optimization (PSO) based Support Vector Machine (SVM) technique is also compared with the Bayesian network model that outperforms in prediction accuracy.
An Improved Classification Analysis on Utility Aware K-Anonymized Dataset
Authors: Verma Kishore S. , Rajesh A. , Johnsana Adeline J. S.
Published: April 2019

K anonymization is one of the worldwide used approaches to protect the individual records from the privacy leakage attack of Privacy Preserving Data Mining (PPDM) arena. Typically anonymized dataset will impact the effectiveness of data mining results. Anyhow, currently researchers
of PPDM progress in driving their efforts in finding out the optimum trade-off between privacy and utility. This work tends in bringing out the optimum classifier from a set of best classifiers of data mining approaches that are capable enough in generating value-added classifying results
on utility aware k-anonymized data set. We performed the analytical approach on the data set that are anonymized in sense of accompanying the anonymity utility factors like null values count and transformation pattern loss. The experimentation is done with three widely used classifiers HNB,
PART and J48 and these classifiers are analysed with Accuracy, F-measure, and ROC-AUC which are literately proved to be the perfect measures of classification. Our experimental analysis reveals the best classifiers on the utility aware anonymized data sets of Cell oriented Anonymization
(CoA), Attribute oriented Anonymization (AoA) and Record oriented Anonymization (RoA).
A Demo of a Platform as-a-Provider for Internet of Factors Packages Provisioning in Hybrid Cloud/Fog Environment
Authors: Sasikumar D. , Saravanakumar S.
Published: April 2019

This demo will show the important thing capabilities of a Platform as-a-provider (PaaS) we've proposed in a research paper widely wide-spread for presentation at IEEE LANMAN 2016 conference. The proposed PaaS allows IoT packages provisioning in hybrid cloud/fog environments. Two desires
are assigned to the demo. On the one hand, we will highlight how IoT programs may be provisioned in such environments. However, we will display concretely the benefits those hybrid environments have over conventional cloud environments. The provisioning in these hybrid environments permits
latency discount and processing performance enhancement. Certainly, a good way to lessen latency, the programs can have a number of its additives strolling in cloud and interacting with the other additives going for walks within the fog, toward IoT devices.
Prediction of Responses in FSW Processed Hybrid Composites Using Soft Computing Technique
Authors: Samuel Diju G. , Ramanan G. , Raja Bino Prince D.
Published: April 2019

In this research a proper step taken to predict friction stir welding process parameters for the aluminium hybrid composites. In FSW Weld quality is influenced by welding input parameters. The welding parameters taken for this work are axial load, tool profile, spindle speed and material
composition. In the present work different combination of aluminium hybrid composite of 6 mm thick is attempted to weld using vertical milling machine. By taking the input parameters such as axial load, tool profile, spindle speed and material composition whereas the response of the model
tensile strength and hardness is calculated. The ANN was trained with experimental data. Testing of the ANN is carried out using experimental data not used during training. The result shows the comparison of experimental values of tensile strength and hardness and predicted value using ANN.
This indicates that the developed neural network can be used as alternative way for calculating mechanical properties for given process.