bluuebunny/crossref_metadata_2025 huggingface dataset:
Development and Validation of a Multiparametric Semiquantitative Scoring System for the Histopathological Assessment of Ischaemia Severity in Skeletal Muscle
Authors: Sanz-Nogués Clara , Creane Michael , Hynes Sean O. , Chen Xizhe , Lagonda Christine Ayu , Goljanek-Whysall Katarzyna , O’Brien Timothy
Published: March 2023

Skeletal muscle is one of the most abundant and dynamic tissues of the body, with a strong regenerative capacity. Muscle injuries can occur as a result of a variety of events, including tissue ischaemia. Lower limb ischaemia occurs when there is an insufficient nutrient and oxygen supply, often caused by stenosis of the arteries due to atherosclerosis. The aim of this study was to develop and validate a multiparametric scoring tool for assessing ischaemia severity in skeletal muscle in a commonly used preclinical animal model. Tissue ischaemia was surgically induced in mice by ligation and excision of the femoral artery. Calf muscles were carefully dissected, prepared for histological analysis, and scored for inflammation, fibrosis, necrosis, adipocyte infiltration, and muscle fibre degeneration/regeneration. Kendall’s coefficient of concordance (W) showed a very good agreement between the appraisers when scoring each individual histological feature: inflammation (W = 0.92,

p
≤
0.001

), fibrosis (W = 0.94,

p
≤
0.001

), necrosis (W = 0.77,

p
≤
0.001

), adipocyte infiltration (W = 0.91,

p
≤
0.001

), and fibre degeneration/regeneration (W = 0.86,

p
≤
0.001

). Intrarater agreement was also excellent (W = 0.94 or more,

p
≤
0.001

). There was a statistically significant negative association between the level of muscle ischaemia damage and the calf muscle weight and skeletal muscle fibre diameter. Here, we have developed and validated a new multiparametric, semiquantitative scoring system for assessing skeletal muscle damage due to ischaemia, with excellent inter- and intrarater reproducibility. This scoring system can be used for assessing treatment efficacy in preclinical models of hind limb ischaemia.
Improving the Probability of Stroke Detection inside the Human Head Using Wideband Polarimetric Synthetic Aperture Radar Imaging
Authors: Naghavi Amir H. , Hassani Hamid R. , Oloumi Daniel
Published: March 2023

This paper presents an imaging system based on ultrawideband microwave radars for the detection of bleeding regions and strokes inside the human head. The proposed system is portable and focuses on revealing bleeding areas with unpredictable shapes using polarimetric data acquisition. A custom-designed dual-polarized bowtie patch antenna capable of pumping the UWB pulses inside the patient’s head is designed and presented as the biomedical sensor for the system. The antenna dimensions are

25
×
25
 
m

m

2

. It mitigates the mismatch between the air and skin needles of any coupling liquid, resulting in safe SAR levels below 0.5 W/kg and wideband operating bandwidth that covers 1.2-4.5 GHz with unidirectional radiations. To collect the raw polarimetric data, an elliptical array of the proposed antenna is formed around the patient’s head model that includes 16 elements in direct contact with the phantom. The performance of the proposed method is validated through an imaging scenario with two nonuniform bleeding areas inside the patient head model. The whole structure is simulated with a Gaussian pulse as the excitation using CST Microwave Studio tools. To produce 2D images of the voxel model, the time-domain elliptical synthetic aperture radar (ESAR) imaging algorithm is applied. Accurately detecting the presence and shape of anomalies in reconstructed images using the proposed method demonstrates the efficiency of the proposed system and determines its advantages over single-polarization systems.
Pilot Maneuvering Performance Analysis and Evaluation with Deep Learning
Authors: Zhang Shiwen , Huo Zhimei , Sun Yanjin , Li Fujuan , Jia Bo
Published: March 2023

Quick access recorder (QAR) data have been used to evaluate pilot performance for decades. However, traditional evaluation methods suffer from the inability to consider multiple parameters simultaneously, and most of them need to select features manually in advance. To study the relationship between QAR data and pilot performance, this paper puts forward one-dimensional convolutional neural networks (1-D CNN) which consider QAR metrics in an integrated manner. This paper obtained indicators describing the operational status of an aircraft first. Then, the correlation between indicators and pilot performance (skill levels) was studied. Inspired by the fact that CNN can extract both local and global features, this paper has developed an approach to achieve the state-of-the-art result in pilot performance evaluation, which was tested on operating data of Boeing 737. The results prove that other methods do not work well, while the 1-D CNN improves the prediction accuracy of 5 pilot skill levels. Besides, when it is used on a binary classification problem, the result improves to 78.18%. Finally, the indicators were grouped into 5 common factors by factor analysis and fed into 1-D CNN in different combinations. Each common factor plays a different role in pilot performance evaluation, which can provide advice for the future.
The Microbial Terroir of the Nemea Zone Agiorgitiko cv.: A First Metataxonomic Approach
Authors: Kazou Maria , Pagiati Lena , Dotsika Elissavet , Proxenia Niki , Kotseridis Yorgos , Tsakalidou Effie
Published: March 2023

Vitis vinifera L. cv. Agiorgitiko is one of the most popular indigenous wine grape varieties in Greece, cultivated almost exclusively in the Nemea Protected Designation of Origin (PDO) zone. Here, the microbiota of soil, grapes, and wine, during controlled (CF) and spontaneous (SF) fermentations of Agiorgitko cv. from three vineyards in the PDO Nemea zone were explored, using both classical microbiological analysis and metataxonomics to get evidence about the microbial terroir of the PDO Nemea zone. The classical microbiological analysis revealed higher total mesophilic counts in soil, while in both grapes and wine samples, yeasts prevailed. Lactic acid bacteria and acetic acid bacteria counts were lower in grapes compared to wine and soil. Metataxonomic analysis revealed that, regarding yeasts/fungi, genera Fusarium, Sarea, and Alternaria dominated in soil; Aureobasidium, Cladosporium, and Penicillium in grapes; Saccharomyces in wine during CF; and Hanseniaspora and Saccharomyces in wine during SF. Regarding bacteria, genera Skermanella, Acidobacterium, and Ohtaekwangia dominated in soil, Sphingomonas, Micrococcus, and Rubrobacter in grapes, while Tatumella, Alcanivorax, and Komagateibacter in wine during both CF and SF. Finally, the factors that significantly influence the microbiota of soil, grapes, and wine samples were assessed, and potential microbial biomarkers were identified for the first time in a Greek grape variety.
Clonal Evolution in Healthy and Premalignant Tissues: Implications for Early Cancer Interception Strategies
Authors: Rane Jayant K. , Frankell Alexander M. , Weeden Clare E. , Swanton Charles
Published: March 2023

Histologically normal human tissues accumulate significant mutational burden with age. The extent and spectra of mutagenesis are comparable both in rapidly proliferating and post-mitotic tissues and in stem cells compared with their differentiated progeny. Some of these mutations provide increased fitness, giving rise to clones which, at times, can replace the entire surface area of tissues. Compared with cancer, somatic mutations in histologically normal tissues are primarily single-nucleotide variations. Interestingly though, the presence of these mutations and positive clonal selection in isolation remains a poor indicator of potential future cancer transformation in solid tissues. Common clonally expanded mutations in histologically normal tissues also do not always represent the most frequent early mutations in cancers of corresponding tissues, indicating differences in selection pressures. Preliminary evidence implies that stroma and immune system co-evolve with age, which may impact selection dynamics. In this review, we will explore the mutational landscape of histologically normal and premalignant human somatic tissues in detail and discuss cell-intrinsic and environmental factors that can determine the fate of positively selected mutations within them. Precisely pinpointing these determinants of cancer transformation would aid development of early cancer interventional and prevention strategies.
Clinical Profile of Turner Syndrome: A Tertiary Center Experience
Authors: Soodhana Mohan Dhanya , Hegde Avani , Hebbal Nagarajappa Vani , Palany Raghupathy
Published: March 2023

Background: Turner syndrome (TS) is the commonest chromosomal abnormality in females with an incidence of 25–50 per 100,000 females. Girls with TS universally have short stature (95%), along with gonadal failure (>90%) and infertility (99%); however, the ethnic differences are not well elaborated. Objectives: This study has been planned to evaluate the presentation and course of Indian girls with TS. Methods: Patients with TS presenting to our referral endocrinology clinic were included in this study. Diagnosis of TS was done by karyotyping. A retrospective chart review of these patients formed the basis of this study. Results: A total of 55 patients with TS karyotype were seen, and the mean age at diagnosis was 12.3 years. The commonest presenting features were short stature alone seen in 37 (65.45%) and short stature with delayed puberty in 18 (32.72%). The earliest age at presentation was 4.5 years who presented with short stature. The mean height was 124.17 cm and mean BMI 17.54 kg/m2. The most common karyotype was 45, XO found in 34 (61.6%) of the cases. 15 (27.27%) the cases were started on growth hormone therapy. 26 cases (47.27%) required pubertal induction. Conclusion: A vast number of cases with TS in India remain undiagnosed until puberty or present very late. A high degree of clinical suspicion can help us diagnose these children earlier. If TS is diagnosed earlier, growth can be achieved up to their maximum potential. Early identification and management will help us provide multidisciplinary care and hence prevent complications.
Oral Health Knowledge, Attitudes, and Practices of Individuals with Diabetes Mellitus in the Sultanate of Oman
Authors: Al Shihi Noora , Al Rawahi Abdulhakeem , Al Jahdhami Raya , Al Riyami Rayyan , Al Murazza Abdulaziz , Al Busaidi Noor , Al Riyami Fatma , Al Salti Suad
Published: March 2023

Introduction: Diabetes mellitus is a chronic disease with an increasing global prevalence. The condition has several oral health implications, with oral health in turn affecting diabetes control. People with diabetes are at higher risk of oral health problems, including periodontal disease, dental caries, and candidiasis; in particular, there appears to be a two-way relationship between periodontitis and blood glucose control. While previous research has indicated that diabetics have poor awareness of oral health, there is a gap in the literature from the Sultanate of Oman. This study aimed to determine oral health knowledge, attitudes, and practices among Omani diabetics. Materials and Methods: A cross-sectional study was conducted using a convenience sample of 400 adult Omani diabetics who attended the outpatient clinic of the National Diabetes and Endocrine Center, Oman, in the period between May 2019 and May 2020. A self-administered, Arabic language questionnaire to assess oral health knowledge, attitudes, and practices was developed and validated. Mean scores were calculated to determine overall levels of oral health knowledge, attitudes, and practice. Ethical approval was obtained from the Center of Studies and Research of the national Ministry of Health. Results: A total of 136 (34.0%) male and 264 (66.0%) female Omani adult diabetics participated in the study. The majority of participants (76.8%) demonstrated poor knowledge of oral health, especially with regards to complications like gingivitis (32.4%), dental caries (27.3%), halitosis (27.1%), and gingival abscesses (21.5%). Moreover, most (76.6%) were unaware that oral diseases affected glycated hemoglobin levels. In terms of practices, more than half (54.74.8%) routinely brushed their teeth twice a day. However, only 14.6% and 12.6% regularly flossed and used mouthwash, respectively. With regards to attitudes, 0.5%, 23.8%, and 75.8% of the participants demonstrated poor, moderate, and good attitudes toward oral health, respectively. Smokers more frequently demonstrated poor attitudes compared to nonsmokers (6.3% vs. 1.6%). Conclusion: Omani adults with diabetes mellitus demonstrated poor to moderate levels of oral health knowledge. Various studies conducted elsewhere around the world have similarly shown that diabetics have limited knowledge and awareness of oral health. Oral self-care behaviors are imperative to minimize the risk of oral health complications associated with diabetes. Previous researchers have shown that education is an effective method of reducing the incidence and burden of diabetes-related oral health complications. Thus, additional multidisciplinary initiatives are needed to raise awareness of good oral hygiene practices among diabetics in Oman.
Nephropathy Is Aggravated by Fatty Acids in Diabetic Kidney Disease through Tubular Epithelial Cell Necroptosis and Is Alleviated by an RIPK-1 Inhibitor
Authors: Yu Qi , Chen Ying , Zhao Youlu , Huang Shuo , Xin Xiaohong , Jiang Lei , Wang Hui , Wu Wenyan , Qu Lei , Xiang Chengang , Wang Suxia , Liu Gang , Yang Li
Published: March 2023

Introduction: Diabetic kidney disease (DKD), one of the leading causes of end-stage renal disease, has complex pathogenic mechanisms and few effective clinical therapies. DKD progression is accompanied by the loss of renal resident cells, followed by chronic inflammation and extracellular matrix deposition. Necroptosis is a newly discovered form of regulated cell death and is a major form of intrinsic cell loss in certain diabetic complications such as cardiomyopathy, intestinal disease, and retinal neuropathy; however, its significance in DKD is largely unknown. Methods: In this study, the expression of necroptosis marker phosphorylated MLKL (p-MLKL) in renal biopsy tissues of patients with DKD was detected using immunofluorescence and semiquantified using immunohistochemistry. The effects of different disease-causing factors on necroptosis activation in human HK-2 cells were evaluated using immunofluorescence and Western blotting. db/db diabetic mice were fed a high-fat diet to establish an animal model of DKD with significant renal tubule damage. Mice were treated with the RIPK1 inhibitor RIPA-56 to evaluate its renal protective effects. mRNA transcriptome sequencing was used to explore the changes in signaling pathways after RIPA-56 treatment. Oil red O staining and electron macroscopy were used to observe lipid droplet accumulation in renal biopsy tissues and mouse kidney tissues. Results: Immunostaining of phosphorylated RIPK1/RIPK3/MLKL verified the occurrence of necroptosis in renal tubular epithelial cells of patients with DKD. The level of the necroptosis marker p-MLKL correlated positively with the severity of renal functional, pathological damages, and lipid droplet accumulation in patients with DKD. High glucose and fatty acids were the main factors causing necroptosis in human renal tubular HK-2 cells. Renal function deterioration and renal pathological injury were accelerated, and the necroptosis pathway was activated in db/db mice fed a high-fat diet. Application of RIPA-56 effectively reduced the degree of renal injury, inhibited the necroptosis pathway activation, and reduced necroinflammation and lipid droplet accumulation in the renal tissues of db/db mice fed a high-fat diet. Conclusion: The present study revealed the role of necroptosis in the progression of DKD and might provide a new therapeutic target for the treatment of DKD.
Skin Physiology, Mucosal Functions, and Symptoms Are Modulated by Grass Pollen and Ozone Double Exposure in Allergic Patients
Authors: Fluhr Joachim W , Stevanovic Katarina , Joshi Priyanka , Bergmann Karl-Christian , Herzog Leonie S. , Alwaheed Yasmeen , Al Sowaidi Shirina , Zuberbier Torsten
Published: March 2023

Introduction: Along with climate changes, we see an increase in allergic symptoms and the number of pollen-allergic patients in many countries. Increased allergic symptoms are associated with an elevated ozone exposure which may be linked by impaired epithelial barrier function. This study aimed to quantify the clinical effect of ozone and pollen double exposure (DE). We tested whether ozone impairs barrier-related skin physiology and mucosal functions under DE with pollen in grass pollen-allergic patients versus healthy controls. Methods: This case-control study included 8 grass pollen-allergic patients and 8 non-allergic healthy subjects exposed to grass pollen and ozone in the GA2LEN pollen chamber, comparing shorter and longer DE duration. Non-invasive skin physiological parameters were assessed, including stratum corneum hydration, skin redness, surface pH, and basal transepidermal water loss as a parameter for epidermal barrier function. The subjects’ general well-being, bronchial, nasal, and ocular symptoms were documented. Results: Skin physiology tests revealed that DE in allergic patients deteriorates the epidermal barrier function and increases the surface pH and skin redness. DE significantly induced nasal secretion in pollen-allergic versus healthy subjects, which was more pronounced with longer DE. The general well-being was significantly impaired under DE versus pollen or ozone alone, with a negative influence of DE duration. No relevant bronchial symptoms were recorded. Conclusion: Skin physiology and nasal mucosal symptoms are negatively affected by ozone and grass pollen DE in allergic patients. The negative effects showed, in some parameters, a dose (time)-response relationship. The pH can be regarded as a possible modulatory mechanism.
Segmenting the eating behaviour of university students using the K-means algorithm
Authors: Quiñones Huatangari Lenin , Cueva Ríos María Alina , Huerta Camones Rafaela Teodosia
Published: March 2023

Universities that teach arts education do not only teach how to play an instrument or conduct musical ensembles; they are agents of change in eating behaviour for the praxis of teaching and dissemination of healthy education. The objective of the research was to segment the eating behaviour of students of the artistic education-music speciality of the National University of Education "Enrique Guzmán y Valle" by applying the K-means algorithm. To do this, the methodology consisted of understanding the problem, understanding the data collected, preparing the data, modelling and evaluating the model. For modelling, the free software Weka was used through the K-means clustering technique on a data matrix of 148 instances with forty-three nominal variables collected online based on an instrument designed and validated to assess eating behaviour in university students. Two was determined to be the optimal clustering for eating behaviour in university students, using the elbow method, with a distribution of 49% for the first cluster and 51% for the second cluster. The results of the study population showed that the eating behaviour of university students is adequate.
A Chameleon algorithm for solving economic dispatch problem in microgrid system
Authors: Zahraoui Younes , Alhamrouni Ibrahim , Mekhilef Saad , Korõtko Tarmo , Jusoh Awang , Sutikno Tole
Published: March 2023

The economic power dispatch (ED) is considered a critical optimization issue in the power system and microgrid. There are several objectives through the economic load dispatch issues such as reducing the operating cost, total emission, or start-up operations. This paper presents a Chameleon swarm algorithm (CSA) for determining the optimal ED of distributed energy resources (DER) in the microgrid. The proposed technique numerically mimics and executes chameleons' behavioral processes to their quest for food, such as their action for rotating their eyes to identify and grab prey using the speed of their sticky tongues. In this study, the CSA has been applied to obtain the optimal power dispatch from DER using the photovoltaic (PV) plants, combined heat power (CHP) systems, and traditional diesel generators. The obtained results from the simulation are compared with the conventional metaheuristic algorithms which have been used in previous studies, such as particle swarm optimization (PSO), genetic algorithm (GA), and artificial bee colony (ABC). Experimentally, the proposed algorithm for solving the ED problem determined the best value of the power dispatch and high performance compared to other metaheuristics methods.
The one-phase SrMg2La2W2O12:Tb3+, Sm3+, Tm3+ phosphor and its optical features in multicolor and white-illumination LEDs
Authors: Tung Ha Thanh , Dang Huu Phuc , That Phung Ton
Published: March 2023

Researchers propose the phosphors emit many colors SrMg2La2W2O12:Tb3+, Sm3+, Tm3+ (SMLLW:RE3+) (RE3+=Tb3+, Sm3+, Tm3+) synthesized using the solid-status reacting technique as promising downward-transformation luminous substances for diodes emit white illumination and screens in the current study. The structural and binding data given by X-ray diffraction (XRD) data and fourier transform infrared (FTIR) spectroscopy suggest the corresponding orthorhombic configuration and vibrational powers, respectively. The stimulation and radiation bands of color of SMLLW:RE3+ phosphor show that such phosphors may be successfully stimulated via ultraviolet (UV) illumination and generate green, orange-red, and blue (stands for G, O-R, B) illumination, in turn. For different doses of the triggers Tb3+, Sm3+, and Tm3+ within the SMLW phosphor base, luminescence, decomposition periods, Commission Internationale De L'eclairage (CIE) color coordination, along with correlated hue heats (Tcct) are specified. When a triple-doped SMLW phosphor is activated using a ligand-to-metal charge transition (LMCT), it produces G, O-R, B hues at the same time and can be adjustable to white light, according to the results. An effective power transfer among rare-earth ions was found and investigated using decay curve analysis. According to the findings, SMLW:RE3+ (RE=Tb, Sm, Tm) are suitable options to use for light-emitting diodes (LEDs) and screens creation.
Abnormal heart rate detection through real-time heart monitoring application
Authors: Hashim Ummi Namirah , Salahuddin Lizawati , Hashim Ummi Rabaah , Naim Mohd Hariz , Raja Ikram Raja Rina , Abdul Rahim Fiza
Published: March 2023

Health monitoring that requires doctors and patients at the healthcare center may not be practical during the coronavirus disease 2019 (COVID-19) pandemic. Alternatively, mobile health (mHealth) should be embraced to minimize contact between patients and healthcare personnel. This research aims to enhance the detection of abnormal heart rate (HR) detection by developing a real-time heart rate monitoring (RTHM) application. Sixteen healthy adults participated in a physical real-time HR monitoring testbed. Participants HR was measured for three minutes resting and three minutes performing moderate-intensity physical activity. The results were compared with the polar beat app. Additionally, the energy consumption, the time taken to receive an alarm message, and an acceptance test were analyzed. The app is acceptably accurate, the mean absolute percentage error less than 2%. The response time to receive the alarm message is 30 seconds on average, which is under an acceptable range of medical standards. Moreover, the app is power efficient, 477 mW on average. Participants show a positive attitude towards using RTHM. RTHM is expected to provide a more plausible tool for monitoring the heart towards enhancing abnormal HR detection by promoting patient-oriented healthcare and minimizing sudden deaths due to heart failure.
SrAlOCl:Bi3+@SiO2 phosphor with broad emission band and its effects on LED optical power and correlated color temperature
Authors: Tung Ha Thanh , Dang Huu Phuc , Nhan Hoang Thinh
Published: March 2023

Sr3Al2O5Cl2:Bi3+ (SAlOCl:Bi3+)phosphor for broadband emission was made using a solid-state method. From the extensive spectroscopic analysis and theoretical computation, significant conclusions about the origin of the Bi3+ emission were drawn. For the Sr 3 and Sr 1 sites, respectively, the dipole-quadrupole and quadrupole-quadrupole interactions were responsible for the concentration quenching in SAlOCl:Bi3+. The resulting luminescence mechanism demonstrated that the crystallization of Bi3+ at the two sites is what causes the emission from each site. The warm white light emitting diodes (LED) models were built with a 380-nm ultraviolet (UV) chip, SAlOCl:Bi3+, and two other phosphors. Then, the color rendering indeces (CRI) and the correlated color temperature (CCT) were calculated. Particularly, the CRI values ranged from 84.3 to 86.2 under operating currents of 20–50 mA, respectively. The increasing SAlOCl:Bi3+ dosage also heightened particle density, resulting in higher scattering coefficients. High scattering results in improved color coordination (lower color variance). The CRI and luminous flux are reduced as the phosphor SAlOCl:Bi3+ concentration increases more than owing to color loss and energy loss by backscattering and re-absorption. Thus, it is advisable to consider SAlOCl:Bi3+ carefully before applying in production.
Implementation of blended learning approach in teaching introductory computer science course
Authors: Obeidat Alaa , Yaqbeh Rola
Published: March 2023

Information communication and technology has great impact on modern education architecture of 21st century. This research intends to analyze the effectiveness of blended learning considering its basic principles and factors. Also, this study is focused on determining core problems of blended learning thus highlighting its design approach. A descriptive and inferential statistical analysis has been conducted on the data that reveal that the majority of students prefer blended learning system regardless their major, gender and any other factors if they have good infrastructure and effective electronic platform. It is recommended that for effective implementation of blended system there should be opportunities of face to face as well as online synchronous, and non-synchronous communication between students and teachers.
Use of mobile applications in citizen security
Authors: Chumbe Chocce Juan , Andrade-Arenas Laberiano , Hernández Celis Domingo , Cabanillas-Carbonell Michael
Published: March 2023

An abstract is often presented separately from the article, so it must be able to in the following article the use of the mobile application is recommended as a tool that serves public safety because currently crimes of extortion and fraud are committed by making false calls to people's mobile devices. Therefore, the objective of this research is to help families with their welfare and safety and motivate the use of mobile applications. In the present work the situation, task, action, dan result (STAR) methodology was applied to elaborate the present work, this technique will allow improving the difficulties of the people. This methodology is very important because it is used to evaluate the circumstances in which people find themselves, a sequence must be followed to achieve the proposed objectives. The result obtained is an average of 84.5% on the design of the mobile prototype; being approved by the experts. The beneficiaries of the research are citizens through the mobile application.
Reactive power planning with the help of multi-objective genetic algorithm and flexible AC transmission systems devices
Authors: Hooda Prince , Saini Mukesh Kumar
Published: March 2023

In this paper power quality of 3-bus solar-based hybrid system has been presented (where one or more than one distribution generator unit is connected to the grid). The injection of solar power into grid-connected systems creates power quality problems such as current consistency, electrical fluctuations, and inefficient power demand. A power quality control strategy based on a real-time self-regulation method for autonomous microgrid operation has been presented. In this paper solar farm design and satisfactory performance tests such as PV-static synchronous compensator (STATCOM) to improve the power quality of grid-based systems have been presented using the MATLAB/Simulink environment. Pulse width modulator (PWM) with proportional-integral derivative (PID) controller used for frequency control, reactive var compensation is used to control voltage profile. Multi-objective genetic algorithm (MOGA) for reactive power planning (RPP) with the objective of reactive power minimization is introduced. The optimization variables are generator voltage, transformer tap changer, and various operational constraints.
Improve PV-diesel operating management system considering sun availability time
Authors: Syafii Syafii , Muhardika Muhardika , Laksono Heru Dibyo
Published: March 2023

This paper presents a hybrid photovoltaic (PV)-diesel management system performance analysis considering weather conditions. The system is designed to operate based on charging current, battery capacity, and loading current. During charging current is decreased but the battery capacity is high, and the PV system remains supplied for low and medium loading current. When the charging current is lowered and the battery capacity is in the middle, the PV system still supplies for low loading current. However, when the charging current decreases and the battery voltage decreased below 22.3 volts, the supply instantly switches to the diesel generator. The charge current is calculated by subtracting the PV current from the load current. A real-time clock is implemented as a timer to guarantee that there is no repetitive switching throughout the night when charging from the panel is missing. The system works automatically through microcontroller control during the day for 9 hours. The improvement that has been obtained is to overcome the problem of repeated switching processes by limiting the transfer process back to PV when sunlight is not available.
Pneumonia-Induced Inflammation, Resolution and Cardiovascular Disease: Causes, Consequences and Clinical Opportunities
Authors: Stotts Cameron , Corrales-Medina Vicente F. , Rayner Katey J.
Published: March 2023

Pneumonia is inflammation in the lungs, which is usually caused by an infection. The symptoms of pneumonia can vary from mild to life-threatening, where severe illness is often observed in vulnerable populations like children, older adults, and those with preexisting health conditions. Vaccines have greatly reduced the burden of some of the most common causes of pneumonia, and the use of antimicrobials has greatly improved the survival to this infection. However, pneumonia survivors do not return to their preinfection health trajectories but instead experience an accelerated health decline with an increased risk of cardiovascular disease. The mechanisms of this association are not well understood, but a persistent dysregulated inflammatory response post-pneumonia appears to play a central role. It is proposed that the inflammatory response during pneumonia is left unregulated and exacerbates atherosclerotic vascular disease, which ultimately leads to adverse cardiac events such as myocardial infarction. For this reason, there is a need to better understand the inflammatory cross talk between the lungs and the heart during and after pneumonia to develop therapeutics that focus on preventing pneumonia-associated cardiovascular events. This review will provide an overview of the known mechanisms of inflammation triggered during pneumonia and their relevance to the increased cardiovascular risk that follows this infection. We will also discuss opportunities for new clinical approaches leveraging strategies to promote inflammatory resolution pathways as a novel therapeutic target to reduce the risk of cardiac events post-pneumonia.
Sex Disparities in Diagnostic Evaluation and Revascularization in Patients With Acute Myocardial Infarction—A 15‐Year Nationwide Study
Authors: Ashraf Muddasir , Jan M. Fuad , Bajwa Tanvir. K , Carnahan Ryan , Zlochiver Viviana , Allaqaband Suhail Q.
Published: March 2023

Background

Although sex disparities in the diagnostic evaluation and revascularization of patients with acute myocardial infarction are well documented, no study has evaluated longitudinal trends in these disparities.

Methods and Results

Using the National Inpatient Sample from 2005 to 2019, 9 259 932 patients with acute myocardial infarction were identified. We divided 15 years into five 3‐year periods. The primary objective was to evaluate sex‐based trends in the use of diagnostic angiography, percutaneous coronary intervention, and coronary artery bypass graft (CABG) among patients with non–ST‐segment–elevation myocardial infarction and ST‐segment–elevation myocardial infarction (STEMI) over 15 years. The secondary objective was to evaluate sex disparities in mortality, length of stay, and cost. For non–ST‐segment–elevation myocardial infarction, we saw a small reduction in sex disparity in the use of all diagnostic angiography in period 5 versus period 1 (4% versus 5.3%;
P
<0.01), no change in sex disparity in percutaneous coronary intervention use in period 5 versus period 1 (5.6% versus 5%;
P
=0.16), and a widening sex disparity in CABG in period 5 versus period 1 (5.4% versus 4.4%;
P
<0.01). However, we noted decreasing sex disparities in the use of diagnostic angiography, percutaneous coronary intervention, and CABG for ST‐segment–elevation myocardial infarction in mostly all periods compared with period 1 (
P
<0.05, all comparisons), but differences still existed in period 5. Risk‐adjusted in‐hospital mortality was higher after CABG for non–ST‐segment–elevation myocardial infarction and after percutaneous coronary intervention and CABG for ST‐segment–elevation myocardial infarction in women than men.

Conclusions

Despite variable trends in sex disparities in diagnostic and revascularization procedures for acute myocardial infarction, disparities still exist.
The Interrogative Left Periphery: How a Clause Becomes a Question
Authors: Dayal Veneeta
Published: March 2023

Question meaning is built up at three points in the interrogative left periphery. An interrogative is differentiated semantically from a declarative at CP. It becomes a request for information by the speaker, directed toward the addressee, at SAP (Speech Act Phrase). In between is PerspP (Perspective Phrase), which introduces PRO, an individual for whom the interrogative CP is potentially active. PRO is the perspectival center, the individual from whose point of view the interrogative can be a request for information. When the speaker argument in SAP binds PRO, we get a matrix question. When a matrix subject binds PRO, we get quasi-subordination. Quasi-subordination is a hybrid between true subordination (with respect to pronominal interpretation, for example) and matrix questions (with respect to intonation, for example). Restrictions on quasi-subordination are regulated by, in addition to standard selectional restrictions, semantic compatibility between the implied ignorance of the individual who is the perspectival center of the question and the meaning of the embedding clause. Empirical support for this view of the interrogative left periphery comes from a range of phenomena from unrelated languages. Several further implications are discussed, making connections to similar proposals about other clause types and to developments in our understanding of how complement selection works.
The EU’s Informal Readmission Agreements with Third Countries on Migration: Effectiveness over Principles?
Authors: Fernando-Gonzalo Elsa
Published: March 2023

Achieving faster and effective returns of irregular migrants is one of the priorities on the Pact on Migration and Asylum proposed by the European Commission. The Commission links the effectiveness of return to the enforcement of return decisions, which, although limited as an analytical benchmark, show that only 30% of return decisions are successful. To improve this ratio, the EU has recently resorted to informal readmission agreements or arrangements with third countries. Through these instruments, the process for binding international agreements established in the Treaties is bypassed. This type of non-binding instrument, generally covered under the ‘soft law’ label, generates major problems for the core principles of the EU legal order of institutional balance, judicial control, and transparency. The aim of this article is to analyse how these acts affect the three main principles of the legal system in the search for a more effective readmission policy using two case studies as the arrangements with Afghanistan and Bangladesh. The article concludes that the avoidance of the three principles does not result in a higher rate of returns.
Theology of Silence
Authors: Reese Naomi Noguchi
Published: March 2023

This article explores Endo Shusaku’s views of God and silence with the aim of sketching what I take to be Endo’s theology of silence. In service of this goal, I will delineate how Japanese culture and events in Endo’s life contributed to shaping his views of God and silence, which ultimately led to Endo’s theology of silence—one fitting his Japanese sensibilities. In Endo’s divine drama of silence, Christ, who is the eternal suffering companion, is the inhabiter of silence, while the Kakure Kirishitans—the oppressed and weary—are the pilgrims of silence. In the space of silence, ultimate beauty is revealed. God does not leave those who suffer alone; they are his to be comforted. Endo’s Christ is ineffectual to deliver from harm, yet he is effectual to comfort those who seemingly cannot be comforted and to love those who are seemingly unlovable.
Toenadering Tot Het Oosterse Christendom
Authors: Ofm.Cap. Zacharias
Published: March 2023

Après avoir précisé Ie vrai but du Concile l'auteur décrit l' état d'esprit des ortho­ doxes et des catholiques occidentaux vers 1959, c' est. dire les changements dans leur mentalité, opérés depuis un siècle, Ensuite il montre comment les réactions des orthodoxes. l'annonce du Concile ont conduit. envoyer des observateurs, surtout du cöté des patriarcats de Moscou et de Constantinople, l' Eglise grecque se tenant. distance, Finalemcnt il discute les rapports entre ces faits et Ie problème qu' on. défini: „Les Eglises orthodoxes devant Ie monde" .
Reacties In Griekenlanden Constantinopel Bij De Opheffing Van De Banvloek
Authors: Stephanou A.A E.
Published: March 2023

Réaclion. la levée de l'anathème en Grèce et. Constanlinople.

Après un exposé détaillé des longues tractations entre l'Eglise catholique et celle de Constantinople, l'auteur décrit Ja cérémonie de la levée. l'Eglise patriarcale du Phanar et donne Ie texte de l'acte patriarcal et synodal. Suivent Jes réactions grecques défavorables de certains milieux d' organisations dites extra-ecclésiastiques qui ont réussi. entrainer dans leur camps Je vieil évêque d' Athènes, et de plusieurs organi­ sations religieuses. Cependant en Grèce les réactions favorables ont été beaucoup plus ,importantes et nombreuses: la grande presse du pays, les facultés de theologie d'Athènes et de Salonique, J'organisation des théologiens laïcs etc. Finalement l'auteur expose brièvement la réaction des chrétiens en Turquie. Il ne cache pas les faits désagréables par fidélité historique mais aussi pour souligner Ie courage du patriarche Athénagoras dont Ja force au milieu de la tempête constitue un phénomène plus qu'admirable.
De Reis van Paus Paulus Vi Naar Konstantinopel En Efeze En De Reacties In Griekenland
Authors: A.A. A. Aarns
Published: March 2023

Le voyage du pape Paul VI. Constantinople et les réactions de la presse hellénique.

Le présent article décrit les étapes du voyage de SS. Paul VI. Constantinople et cite quelques passages significatifs des discours échangés. Les réactions de la presse hel­ lénique sont, dans l' ensemble, favorables. Rares sont les réactions qui marquent encore quelque méfiance.
Christendom in Heden Daags Turkije (III)
Authors: Jacob X.
Published: March 2023

L'auteur continue son étude du christianisme dans la Turquie d'aujourd'hui. Après avoir décrit précédemment les communautés chrétiennes de la Haute-Mésopotamie, de l'est et du sud de l'Anatolie et de la région de la Mer Noire, l'auteur traite, dans Ie présent article, de l'Anatolie centrale (Sivas, Kayseri, Ankara, Konya) et de la région de la Mer Egée. La comrnunauté chrétienne la plus nombreuse est celle d'lzmir (Smyrne), mais elle est presqu'uniquement composée de catholiques latins par suite de l'exode des Grecs (Traité de Lausanne 1923) et des Arméniens persécutés. Il ne reste en Turquie que des îlots chrétiens et qui vont en diminuant. cause d'une lente, mais incessante émigration du christianisme en Turquie au cours des siècles, l'exode grec et arménien n'ayant été que Ie coup de gräce. En toute occurrence, la fidélité des communautés qui ont survécu est digne d'admiration.
Grieks-Melkitisch Patriarchaat van Antiochië op Zoek Naar Zijn Indentiteit
Authors: Raheb Abdallah
Published: March 2023

Le patriarcat grec-melkite dʼAntioche. la recherche de son identité.

Le 31 octobre 1969 fut annoncée la nomination dʼun exarque pour les Melkites catholiques des Etats-Unis. Cʼétait la fin provisoire dʼun différend entre le patriarcat melkite et la Congrégation pour les Eglises orientales.. qui revient le droit de nommer un exarque melkite pour les régions “non-orientales”? Lʼauteur de lʼarticle se basant sur une publication récente,. lʼaide du décret Orientalium Ecclesiarum (Vatican II) examine le sens et le contenu du terme “territoire patriarcal”. En invoquant une Instruction de la Propagande Fide (1789) il croit pouvoir interpréter lʼexpression “les limites du territoire patriarcal” non dans un sens géographique, mais dans un sens numérique et existentiel, cʼest. dire elle indiquerait le nombre suffisant de clergé et de fidèles melkites nécessaire pour former un exarchat. Par conséquent cʼest le patriarche qui peut le constituer et nommer le nouvel évêque puisque la région se trouve. lʼintérieur de son patriarcat. Lʼauteur termine son article en répondant. quelques objections et note quʼau fond il sʼagit dʼun problème ecclésiologique.
De Mozaieken van de S. Marco Te Venetie en de Byzantijnse Ikonografie
Authors: Jacobs A.
Published: March 2023

Les mosaïques de l'église de St. Marc à Venise et lʼiconographie byzantine. Dans cet article lʼauteur nous donne une description détaillée de la décoration de lʼéglise de St. Marc à Venise. Le but en est de découvrir le plan fondamental qui a commandé les travaux des divers artistes. En même temps il veut montrer en quelle mesure les mosaïques obéissent aux règles de lʼiconographie byzantine. Lʼadaptation de ces règles aux exigences de lʼesprit occidental fait de ce monument le point de rencontre de deux mondes. Ici lʼiconographie de lʼOrient et celle de lʼOccident se trouvent unies dans une synthèse vivante.
Ikonografische Aspecten van Het Traditieprobleem
Authors: Tavard G.
Published: March 2023

Aspects iconographiques du problème de la tradition

Pour lʼétude de la tradition dans les premiers siècles on ne se sert ordinairement, dans la méthode historique, que des documents écrits. On peut se demander pourtant sʼil ne faut pas, pour compléter ces documents, recourir davantage aux données de lʼiconographie chrétienne qui permettent de toucher du doigt les conceptions de ce temps. Pour illustrer cette “méthode iconographique” lʼauteur propose une nouvelle interprétation de quelques sarcophages connus. Elle souligne le rôle important que joue dans les premiers siècles lʼidée de la transmission de lʼévangile. Cette transmission porte un double aspect. Lʼobjet de la paradosis nʼest pas seulement une doctrine, mais aussi et avant tout la vie chrétienne ellemême. Cʼest dans cette perspective que les sacrements du baptême et de lʼeucharistie, très souvent représentés dans lʼart primitif, prennent toute leur signification.
Het Herstel van de Grieks-Katholieke Kerk in Tsjechoslowakije
Authors: Lacko S.J. M.
Published: March 2023

Le rétablissement de l'Eglise grecque-catholique en Tchécoslovaquie

Un des fruits les plus importants du ”printemps de Prague” est sans doute le rétablissement de l’Eglise grecque-catholique. Le 13 juin 1968 cette Eglise, supprimée en 1950, est autorisée de reprendre ses activités. Se servant de plusieurs documents authentiques l’auteur trace dans son article l’histoire mouvementée de eet événement. Profitant du prodès de démocratisation qui commence avec Alexandre Dubcek, les Grecs-catholiques essaient d’obtenir la réhabilitation de leur Eglise. Le gouvernement reconnaît la légitimité de leur désir et signe le décret de rétablissement. Cet acte officiel est la cause de nombreuses difficultés. A côté des problèmes internes de l’Eglise rétablie il y a les relations pénibles avec l’Eglise orthodoxe qui voit le nombre de ses fidèles fortement réduit. La situation s’aggrave encore quand, après l’invasion soviétique, il en est fini de la démocratisation et que Ie gouvernement reprend une attitude plutôt hostile.
Athenagoras I, Patriarch van Constantinopel
Authors: van Dieten J. L.
Published: March 2023

Athénagoras I, patriarche de Constantinople

Le 7 juillet 1972 est décédé, déploré par tout Ie monde chrétien, le patriarehe oeeuménique de Constantinople, Athénagoras I. Dans cet article, écrit en l'hon neur du défunt. l'auteur trace les grandes lignes de cette vie inspirée et inspiratrice. Après un bref aperçu sur la période précédant son élection il étudie surtout ses aetivités patriareales. Comme patriarehe de Constantinople Ahénagoras s'est fait remarquer en premier lieu par son travail pour l'unité. Malgré d'innombrables diffieultés il a réussi à agrandir l' unité parmi les Eglises orthodoxes. En même temps il a voué toutes ses forces à un rapproehement grandissant entre l'orthodoxie et les autres Eglises ehrétiennes: Eglises non ehalcédoniennes, Conseil Oecuménique des Eglises, Eglise eatholique romaine. Il n'a pas vu la réalisation de son idéal: Ie rétablissement de l'unité ehrétienne. Mais e'est grâce à lui que l'Eglise a fait de si grands progrès sur la voie de l'unité.
De Ecclesiologische Implicaties van Het Pauselijk Primaat
Authors: Popescu D.
Published: March 2023

Les implications ecclésiologiques de la primauté papale

Pendant plus d'un millénai re l'Eglise orthodoxe et l'Eglise catholique romaine ont formé ensemble l'Eglise une et indivise du Christ. C'est pourquoi l'ecclésiologie catholique et l'ecclésiologie orthodoxe sont très proches l'une de l'autre et ont beaucoup de points communs. Cette origine commune n'a pu empêcher, cependant, que depuis Ie schisme de 1054 l'Eglise catholique a construit son propre système ecclésiologique quiest à peu près irréductible à celui de l'Eglise orientale. La différence fondamentale entre les deux ecclésiologies consiste dans la prétention de la primauté universelle et de l'infaillibilité du pape. Ces deux dogmes de l'Eglise catholique romaine ont influencé profondément les doctrines de Vatican II concernant la Trinité, l'Eglise, la collégialité épiscopale, le peuple de Dieu et l'oecu­ ménisme, et leur donnent une signification que l'Orthodoxie n'est pas capable d'accepter.