bluuebunny/crossref_metadata_2025 huggingface dataset:
Tumores del estroma gastrointestinal (GIST): papel del cirujano en la era de la medicina molecular
Authors: Toro Vásquez Juan Pablo , Madrid Vélez Jorge Alberto
Published: February 2023

Los tumores del estroma gastrointestinal (GIST, por la sigla en inglés de gastrointestinal stromal tumors) son neoplasias no epiteliales del tubo digestivo y del mesenterio caracterizadas por un patrón histológico y de inmunohistoquímica específico. Hasta 1983 se las clasificaba erróneamente como leiomiomas, leiomioblastomas y leiomiosarcomas; en ese año Mazur y Clark acuñaron el término “tumor estromal”. Los GIST constituyen menos del 1% de los tumores malignos del tracto gastrointestinal y el 5% de los todos los sarcomas, con una incidencia de 0,68/100.000 habitantes. Se hadocumentado que estos tumores son el resultado de mutaciones de los protoncogenes c-Kit y PDGFRα que alteran las cascadas de señales intracelulares. Pueden ocurrir desde el esófago hasta el ano y su forma de presentación clínica depende de la localización y el tamaño. Los GIST primarios son de tratamiento quirúrgico, mientras que en la fase avanzada se puede recurrir a la terapia molecular dirigida, luego del desarrollo del mesilato de imatinib. Hay controversia sobre las terapias adyuvante y neoadyuvante. El presente artículo es una actualización sobre los GIST con base en la literatura disponible al respecto.
Oxidative stress parameters in dogs naturally infected with sarcoptic mange
Authors: Emre Yanar Kerim , Kucukler Sefa , Eren Emre , Sertaç Eroglu Muhammed , Ilgun Murat , Gur Cihan , Kandemir Fatih Mehmet , Aktas Mustafa Sinan
Published: February 2023

Background: Scabies is one of the most common diseases in dogs. It threatens both animals and humans due to its zoonotic potential. Objective: The purpose of this study was to evaluate the oxidant/antioxidant balance with hematological findings in dogs infested with sarcoptic mange. Methods: The animals evaluated in this study consisted of 32 mixed-breed dogs between 1 and 2 years of age. The dogs were allocated into two groups: a control group (infestation-free animals; n=10), and a sarcoptic mange-infected group (Sarcoptes, n=22). Dogs in the Sarcoptes group showed infestation signs such as intense itching, excoriations, alopecia, and blistering of the elbow and auricular margins. Results: Significant increase (p<0.01) levels were observed in total oxidant status (TOS), malondialdehyde (MDA), oxidative stress index (OSI), and nitric oxide (NO), while glutathione (GSH) and total antioxidant status (TAS) levels in dogs infested with Sarcoptes decreased significantly (p<0.01). In addition, a significant increase (p<0.01) of WBC count in dogs in the sarcoptic group in comparison with the control was found. Conversely, there was significant decrease (p<0.01) in RBC, HGB, and PCV counts in Sarcoptes-infested dogs. Conclusions: Our study suggests a possible relationship between oxidant/antioxidant imbalance and hematological findings in dogs infested with sarcoptic mange. Furthermore, in addition to MDA, TAS, TOS, and OSI markers, NO as well as GSH might be also used to assess the oxidative stress in dogs naturally infected with Sarcoptes scabiei.
Evaluating the IMERG precipitation satellite product to derive intensity-duration-frequency curves in Colombia
Authors: Rodríguez-Sandoval Erasmo Alfredo , García-Echeverri Camila , González-Ramírez Ana María , Sandoval-Barrera John A. , Patarroyo-González Manuel E. , Agudelo D. Daniela E. , Roldán N. Moisés A.
Published: February 2023

This article explores the potentialities of the IMERG V06B FINAL product for estimating Intensity-Duration-Frequency curves in Colombia, using the in-situ data available for 110 rain gauges. From observed data for 76 of these stations, we validated the satellite IMERG precipitation data for the period 2001-2019, at daily, monthly, and annual resolutions. For 60 stations, better results were obtained for the monthly time aggregation, followed by the yearly and daily scales, suggesting that seasonality is the main rainfall characteristic captured by the product. Concerning the occurrence of daily precipitation, results indicate that both the probability of detection and the probability of false detection are high. In general terms, the comparison between intensities from existing IDF curves and those derived from IMERG showed underestimations of the rainfall intensities for the short durations studied (0.5 and 1 h), with mean relative errors in the range [-69%,+56%], and overestimations for the large durations of 2 and 6 h, with mean relative errors in the range [-61%,+171%]. Results also suggest that the IMERG product at this moment is not able to capture the daily rainfall distribution in most of the stations. Nevertheless, for almost 20% of the rain gauges, located mainly in the Amazon, Orinoco, and Pacific Regions, the analysis showed that the maximum intensities derived from IMERG are within +/-25% relative error, compared with the ones calculated using the traditional approach.
La docencia universitaria en tiempos del COVID-19: un estudio mediante grupos de discusión
Authors: Arévalo Galán Azahara
Published: February 2023

La pandemia conocida como COVID-19 ha influido en la docencia universitaria transformando una realidad presencial en una enseñanza virtual o semipresencial, en la mayoría de los casos. Con el objetivo de descubrir las percepciones y opiniones del alumnado sobre la docencia que han recibido en este contexto, hemos realizado una serie de grupos de discusión como técnica de tipo cualitativo, en el marco de la asignatura de Planificación e Innovación Docente dentro del Grado de Educación Primaria en la Universidad de Córdoba. Dentro de estos lugares de reflexión se han debatido diferentes temáticas: evaluación, coordinación, colaboración, individualismo, profesorado, tipos de modalidad, inconvenientes, problemas encontrados, propuestas de mejora, módulos teóricos y prácticos, evidencias de aprendizaje… El alumnado ha participado de forma voluntaria, abierta y reflexiva expresando sus juicios, los cuales han sido muy constructivos para planificar las próximas docencias, afectadas en igual medida por la crisis sanitaria. Dentro de las reflexiones finales, se concluye principalmente que el alumnado prefiere el seguimiento de las clases presenciales, una evaluación preferentemente práctica y una mayor coordinación entre todas las partes implicadas en el proceso. Estas líneas de debate también han abierto nuevos paradigmas de investigación para futuros trabajos dentro del seno de esta universidad.
Imposturas fotográficas
Authors: Ocaña Ricardo
Published: February 2023

Este ensayo extrae una cita de la obra La cámara lúcida: nota sobre la fotografía, de Roland Barthes, para reflexionar sobre el autorretrato como medio para la creación de realidades ficticias y sobre el retrato como objeto mercantil en el ámbito fotográfico profesional. Ambos aspectos están muy presentes en la sociedad contemporánea, potenciados por el uso indiscriminado de las redes sociales e Internet. A lo largo del texto se realiza una reflexión sobre cada una de las ideas de la cita de Barthes, conectándola con la psicología de la identidad y con la imagen. Transcurridas varias décadas desde su publicación, los pensamientos del autor parecen continuar vigentes en la sociedad actual.
Wealth Stratification and the Insurance Function of Wealth
Authors: Müller Nora , Pforr Klaus , Dräger Jascha
Published: February 2023

This thematic issue examines the insurance function as a mechanism to underlie wealth effects on various outcomes. The articles in this issue shed an innovative light on the insurance function of wealth concerning a range of topics relevant to social stratification and social policy researchers. This editorial provides an overview of the contributions of this thematic issue and highlights some gaps and remaining open questions. Altogether, the contributions suggest that wealth can provide insurance against adverse life events in various contexts. However, this insurance effect depends on welfare state characteristics, wealth portfolios, and the way families handle their wealth.
SAĞLIK ÇALIŞANLARINDA SOSYAL SORUMLULUK ALGISININ ÖRGÜTSEL SÜRDÜRÜLEBİLİRLİĞE ETKİSİNDE KİŞİLİK ÖZELLİKLERİNİN ARACI ROLÜ
Authors: Şimşek Bilgen , Mete Mustafa
Published: February 2023

Aralarında sıkı bir ilişki bulunan, örgüt, örgüt üyeleri ve toplumsal çevre sınırsız bir etkileşim halindedir. Sınırsız istek ve amaçların gerçekleşmesi aşamasında birbirlerine ihtiyaç duyan bu gruplar arasında gizil bir bağdan bahsetmek mümkündür. Bu gizil bağ son dönemlerde çeşitli isimler alarak sergilenen korumacı tutumlarla zati menfaatlere de sahip çıkılmaktadır. Örgütsel sürdürebilirlik kapsamında kurumsal menfaatler örgüt üyelerine empoze edilmektedir. Sosyal sorumluluk projeleri ile toplumsal faydanın arttırılması hedef alınırken bir açıdan krizlerin etki alanından kaçınmak çabası sarf edilmektedir.   Bu kapsamda gerçekleştirilen alan yazım taramasının yanı sıra nicel araştırma yönteminden yararlanarak 467 kişilik örneklem grubuyla anket uygulaması gerçekleştirilmektedir. İstanbul'da özel sağlık işletmelerinde görev alan sağlık çalışanları rastgele örnekleme yöntemi ile seçilmiştir. Demografik Bilgi Formu, Örgütsel Sürdürülebilirlik Ölçeği, Küresel Sosyal Sorumluluk Ölçeği ve On Maddeli Kişilik Ölçeğinden oluşan anket formu 5’li Likert ölçek tipi ve 79 maddeden meydana gelmektedir. IBMM SPSS 26.0 ve AMOS 23.0 paket programlarından yararlanılarak gerçekleştirilen veri analizi sonucunda sağlık çalışanlarında sosyal sorumluluk algısının, örgütsel sürdürebilirliğe etkisinde kişilik özelliklerinin aracı rolü tespit edilmiştir.
Turizm ve Kültürel Miras Kongresi
Authors: Admin Admin
Published: February 2023

Turizm ve Kültürel Miras Kongresi
Perifocal Soft Tissue Reactions in Response to Contaminated Implants With a Composite Antibacterial Coating: Experimental Study
Authors: Savchuk Oleg P. , Tapalski Dmitry V. , Zinovkin Dmitry A. , Nikolaev Vladimir I. , Yarmolenko Maksim A. , Rogachev Aleksandr A.
Published: February 2023

Background. Protection against microbial colonization of surface fixators for metal osteosynthesis can reduce the number of infectious complications.
The aim of the study was to experimentally assess early perifocal tissue reactions to metal implants with a composite antibacterial coating under microbial load.
Methods. Fragments of steel pins for osteosynthesis (diameter 1 mm) with a four-component antibacterial coating based on polylactide, polyurethane, ciprofloxacin and silver nanoparticles were contaminated by methicillin-resistant S. aureus (MRSA) 43431. They were implanted in rats within the quadriceps femoris. Contaminated uncoated pins were used as a control. The animals were withdrawn from the experiment on the 2nd, 4th, 7th day after implantation. Histopathological specimens from tissue around implants were prepared. A semiquantitative assessment of reactions was performed.
Results. The microbial load before implantation was (1.120.26)106 S. aureus cells for the control implants and (0.860.31)106 cells for implants with antibacterial coating. Tissue inflammatory reactions on the second day of implantation were equally evident in the control and investigated groups. There was a significant reduction in the number of immune cells and necrotic detritus, as well as increased growth of connective tissue and neoangiogenesis in the experimental group by the 4th day. The appearance of a less pronounced well-vascularized fibrous capsule around the experimental implants was noted by the 7th day. It indicates a more favorable healing of soft tissues in comparison with the control.
Conclusion. Weak morphological manifestations of tissue reactions in response to the fitting of contaminated implants with an antibacterial coating can be associated with both the direct antimicrobial effect of the coating components and the anti-inflammatory activity of silver nanoparticles and ciprofloxacin included in its composition.
A Close-up Examination of Racial Disparities in Infant and Maternal Outcomes in Montgomery County, Ohio
Authors: Harman Kelsey M. , Reisinger-Kindle Keith M. , Maxwell Rose A.
Published: February 2023

Background: Infant and maternal outcomes in Montgomery County, Ohio, are among the worst in the state and rival that of many low-income nations. This study compares maternal and infant outcomes across 3 zip codes in Montgomery County to discern factors that are influencing health outcomes for their residents. The zip codes represent 3 distinct communities with unique racial and socioeconomic makeups.
Methods: A cohort of mother-infant dyads (n=5098) who delivered at Miami Valley Hospital and Good Samaritan Hospital from January 1, 2009, to January 1, 2019, was analyzed via retrospective chart review. Maternal health outcome composite score (MCS) and infant health outcome composite score (ICS) from Trotwood, Ohio, (zip code 45426) were compared to those of 2 nearby zip codes (45415 and 45424), which were chosen for their lower infant mortality rates and proximity to Trotwood. Continuous variables were compared by ANOVA followed by post hoc Tukey tests. Categorical variables were compared via chi-square analysis.
Results: The MCS and ICS were stratified by zip code and maternal age, race, and BMI. There was a statistically significant difference in MCS for race and BMI across all zip codes, but no statistically significant difference for maternal age. There was no statistically significant difference in ICS across maternal age, race, and BMI.
Conclusion: Maternal outcomes for Black women were consistently worse across communities while outcomes for other races varied. Our study shows that maternal outcomes did not correlate with infant outcomes, indicating that interventions focusing on improving maternal outcomes may be inadequate at addressing infant outcomes. Investigations surrounding race-specific interventions in all populations are needed.
A cross sectional study to determine the correlation of blood glucose and HbA1C in type 2 diabetes mellitus patients
Authors: Baishya Reeta , Bora Madhurima , Mazumdar Arijit
Published: February 2023

Background: Measurement of glycosylated hemoglobin (HbA1c) is considered the gold standard for monitoring chronic glycemic level of diabetes patients. HbA1c is a form of hemoglobin that is measured primarily to identify the average plasma glucose concentration over prolonged periods of time. Levels of HbA1C represent the average blood glucose levels of diabetic patients over the previous 120 days. The objective of this study was to see the correlation between HbA1c levels and glucose levels.
Methods: This cross-sectional study included 60 randomly selected subjects with known diabetes. Both fasting and post prandial blood glucose levels were measured by using venous blood samples. HbA1c levels were measured in venous blood by immunoturbidimetric method. Data were recorded on a proforma in MS-excel sheet. Pearson's coefficient of correlation was applied to find out any significant correlation between the HbA1c levels and the both fasting and postprandial blood glucose levels.
Results: Results were obtained by statistical calculation and plotted with respect to scatter and bar diagram was done and a p<0.05 was considered significant (With 95% CI).
Conclusions: A significant linear positive correlation exists between levels of HbA1C and fasting and post prandial blood glucose.
Biological characterization of a biodegradable scaffold for common bile duct replacement in an experimental model
Authors: Barrera-Mera Baltazar , Barrera-Miranda Ely de los Angeles , Sarmiento-González María José , Abundez-Pliego Ana Lilia , Olivares-Cruz Sandra , Valderrama-Treviño Alan I.
Published: February 2023

Background: The nanofiber scaffolds achieved by the electrospinning technique have been used to develop several biological tissues, the nanofibers obtained by electrospinning procure a favorable microenvironment to mimic the extracellular matrix.
Methods: Study type was of experimental. Study conducted at National Autonomous University of Mexico, from May 2018- May 2022. The protocol was approved by the research and ethics commissions of the UNAM school of medicine. A viscoelastic solution of polylactic-co-glycolic acid (PLGA) and polycaprolactone (PCL) in a 70:30 ratio and gelatin (Gel) in an 80:20 ratio was prepared while a dynamic collector was used with the electrospinning technique.
Results: Mechanical and biological tests were carried out on the scaffold obtained by electrospinning; the resultant scaffold achieves good mechanical matching and structural similarity between the graft and the extrahepatic bile duct.
Conclusions: In this study we managed to create a porous, biocompatible scaffold with good cell adhesion and proliferation, potentially applicable to tissue engineering, especially for the replacement of tubular organs such as blood vessels, bile ducts, and urethra.
Atypical myocardial infarction masquerading as gastroenteritis
Authors: Mahmood Shafqat , Rashid Rahim Abdul , Ali Mohammad
Published: February 2023

Acute coronary syndrome (ACS) encompasses unstable angina and myocardial infarction (MI). MI typically presents as chest pain that may radiate to the arm or jaw and is described as dull, heavy, tight, or crushing. However, it may present atypically with symptoms other than chest pain including epigastric pain, often described as burning in character or like indigestion. This is a case of a 51-year-old patient who presented with symptoms of epigastric pain, nausea and vomiting resembling gastroesophageal disease. The patient was initially evaluated by a physician as a non-urgent case of gastroenteritis. Following further assessment due to ongoing symptoms, he was diagnosed with ST elevation MI (STEMI) and treated according to ACS treatment guidelines. To accurately diagnose ACS, clinicians must demonstrate competent communication, history taking and physical examination skills, identify red flags and make use of appropriate investigations. Correct medications and timely referral to secondary care services is vital to prevent morbidity and mortality.
Adult Burkitt's lymphoma presenting as ileocecal intussusception
Authors: V. Ferreira Nuno , Clara Paulo J. , Pais Jorge M. , Amado Sandra M. , Nobre João M. , Amado Cristina M. , Cunha Fernanda S. , Valente Tânia T. , Ferreira Gonçalo S. , Figueiredo Arnaldo J. , Bárbara Patrícia B. , Santos Miguel C.
Published: February 2023

Most lymphomas of gastrointestinal tract arise mainly in stomach but can affect small bowel. Burkitt’s lymphoma stands for 9% of the cases of primary small intestine lymphoma and clinical presentations may vary. Case report of a 58-years old man presenting an acute abdomen secondary to intestinal obstruction with tomography revealing an ileocecal mass suspicious for intussusception. Surgery was performed and an invaginating mass from ileum-to-cecum lead to a laparoscopic right colectomy. Histopathological analysis established the diagnosis of ileocecal Burkitt’s lymphoma. Post-operative period was uneventful and the patient was referred to oncohematology and started early chemotherapy. Clinical situations of intestinal intussusception or small-bowel masses presenting with obstruction should rise the suspicion for malignancy and the surgeon must be aware of this clinical entity to proceed with an oncologically safe surgery. Intestinal perforation may indicates surgery as it leads to peritoneal tumor spread and indicates a worse prognosis. Laparoscopic surgery approaches must be seriously considered in selected cases. In intestinal lymphoma, early refer to oncohematology for evaluation and treatment is essential and establishes a better prognosis.
Longitudinally extensive transverse myelitis after COVID-19 vaccination in a teenage girl
Authors: Arun Prasad  , Kumar Pradeep , Banerjee Amrita , Ghosh Dipyaman
Published: February 2023

COVID-19 pandemic has led to the development of a variety of vaccines for protection against SARS-CoV-2 infection, with varying safety profiles and protective efficacy. As with other vaccination, vaccination against COVID-19 has also been found to be associated with various kinds of adverse events following immunization. While most adverse effects are mild, some serious side effects like transverse myelitis and acute disseminated encephalomyelitis have also been reported. However, these serious side effects have been reported in adults. To the best of our knowledge, there is no report of longitudinally extensive transverse myelitis (LETM) in the paediatric population, associated with this vaccination. We report here a case of a teenage girl, who was admitted to our hospital with the symptoms of LETM after receiving COVID-19 vaccination. Her diagnosis was based on history and, laboratory and imaging findings. She was discharged after a full recovery.
Development of software for the segmentation of text areas in real-scene images
Authors:   Tomsk Polytechnic University, Lobanova V.A. , Ivanova Yu.A. ,   Tomsk Polytechnic University
Published: February 2023

This article discusses the design and development of a neural network algorithm for the segmentation of text areas in real-scene images. After reviewing the available neural network models, the U-net model was chosen as a basis. Then an algorithm for detecting text areas in real-scene images was proposed and implemented. The experimental training of the network allows one to define the neural network parameters such as the size of input images and the number and types of the network layers. Bilateral and low-pass filters were considered as a preprocessing stage. The number of images in the KAIST Scene Text Database was increased by applying rotations, compression, and splitting of the images. The results obtained were found to surpass competing methods in terms of the F-measure value.
Robust hybrid technique for moving object detection and tracking using cartoon features and fast PCP
Authors:   Sri Siddhartha Institute of Technology, Jeevith S.H. , Lakshmikanth S. ,   Acharya Institute of Technology
Published: February 2023

In various computer vision applications, the moving object detection is an essential step. Principal Component Analysis (PCA) techniques are often used for this purpose. However, the performance of this method is degraded by camera shake, hidden moving objects, dynamic background scenes, and / or fluctuating exposure. Robust Principal Component Analysis (RPCA) is a useful approach for reducing stationary background noise as it can recover low rank matrices. That is, moving object is formed by the low power models and the static background of RPCA. This paper proposes a simple alternative minimization algorithm to fix minor discrepancies in the original Principal Component Pursuit (PCP) or RPCA function. A novel hybrid method of cartoon texture features used as a data matrix for RPCA taking into account low-ranking and rare matrix is presented. A new non-convex function is proposed to better control the low-range properties of the video background. Simulation results demonstrate that the proposed algorithm is capable of giving consistent random estimates and can indeed improve the accuracy of object recognition in comparison with existing methods.
Techniques of sampling the energy characteristics of two-dimensional random signals
Authors:   Bauman Moscow State Technical University, Syuzev V.V. , Proletarsky A.V. ,   Bauman Moscow State Technical University, Mikov D.A. ,   Bauman Moscow State Technical University, Deykin I.I. ,   Bauman Moscow State Technical University
Published: February 2023

The article is devoted to methods of discretization of energy characteristics of two-dimensional random signals when simulating random signals using the original harmonic method, which is a generalization of the well-known algorithm proposed by V. S. Pugachev for the two-dimensional case. Requirements imposed on the sampling method are aimed at reducing the computational complexity of the simulation method and increasing its flexibility thanks to removing restrictions on the form of autocorrelation functions and spectral energy density functions. The use of the simulation error as a criterion for quality assessment is proposed. The discretization method is considered for signals given both on unlimited definition intervals and on limited ones. The article demonstrates results of the software system implementation in which the original simulation method is realized using the described sampling methods in both cases. The proposed technique is shown to be robust and efficient, with the results obtained being of independent scientific and technical value and showing promise for developing new effective spectral techniques of simulating signals for the use in intelligent decision support systems.
Technique of detecting cloudy objects in multispectral images
Authors:   Keldysh Institute of Applied Mathamatics RAS, Nikolaeva O.V.
Published: February 2023

A multistep algorithm to detect cloudy objects in multispectral images is presented. Clustering spatial pixels by the k-means method and applying spectral criteria of cloudy/clear sky to fragments of obtained clusters are carried out in each step of the algorithm. One cloudy object is found in one step. Results of testing the algorithm on images from a sensor HYPERION (199 non-zero spectral bands in a 425 nm – 2400 nm interval under high spatial resolution of 30 m) are given. Images with discontinuous cloud cover above different surfaces (ocean, vegetation, desert, town, snow) are considered. An alternative method, in which the same spectral criteria are applied to each pixel, is also used in testing. Cloud masks obtained by both algorithms are compared. Mean spectra of obtained cloudy objects are given. The presented algorithm finds 1-3 cloudy objects corresponding to the brightness distribution in RGB images. Using the alternative algorithm (without preliminary clustering) leads to detection errors on the cloud edges. Three quality parameters are offered. The ratio of dispersion of "cloudy" spectra to dispersion of "clear" spectra is found to be most informative. This ratio should be much less than 1 when using a good cloudy mask.
Topological charge of superposition of optical vortices described by a geometric sequence
Authors:   IPSI RAS – Branch of the FSRC “Crystallography and Photonics” RAS, Kotlyar V.V. ,   Samara National Research University, Kovalev A.A. ,   IPSI RAS – Branch of the FSRC “Crystallography and Photonics” RAS,   Samara National Research University
Published: February 2023

Here, we investigate coaxial superpositions of Gaussian optical vortices that can be described by a geometric sequence. For all superpositions analyzed, a topological charge (TC) is derived. In the initial plane, the TC can be either integer or half-integer, acquiring an integer value upon free-space propagation of the light field. Generally, the geometric sequence of optical vortices (GSOV) has three integer parameters and one real parameter. Values of these four parameters define the TC of the GSOV. Upon free-space propagation, the intensity pattern of the GSOV is not conserved, but can have intensity petals whose number is equal to one of the four beam parameters. If the GSOV has a unit real parameter, all constituent angular harmonics in the superposition have the same weight. In this case, the TC of the superposition is equal to the average index of the constituent angular harmonics. For instance, if the TC of the first and of the last angular harmonics, respectively, equals k and n, then the total TC of the superposition in the initial plane will be (n + k) /2, becoming equal to n upon free-space propagation.
Recent Studies on the Drug Delivery of Nebulizers - A Review
Authors: Vinoth N. , Bhaskara Rao Lokavarapu
Published: February 2023

This article provides a summary of some of the most current research on the delivery of drugs to the lungs, as well as a discussion of some of the limitations of these studies. Nebulizers have been in use for more than a century to deliver aerosolized drugs to patients suffering from respiratory disorders. Aerosol devices such as these are the best option for people who have trouble managing their inhalation. Because of the actuation required, pressurised Metered-Dose Inhalers (pMDI) and Dry Powder Inhalers (DPI) are unable to generate the necessary inspiratory flow required for successful aerosol drug delivery. Currently, we are looking into how the working mechanism of different nebulizers interacts with the physicochemical features of the formulations. We are looking into a wide range of devices, such as jet, ultrasonic, and vibrating-mesh nebulizers. In this study, the researchers hope to describe the many different types of nebulizers that are currently available on the market, evaluate their performance in aerosol drug delivery, and recommend treatment approaches for patients with chronic obstructive pulmonary disease.
Synthesis, Surface Active Properties and Antimicrobial Activity of Novel Ester – Amidoamine Linked Double Tailed Cationic Surfactants
Authors: Aher Kumudini , Bhagwat Sunil S.
Published: February 2023

Three novel ester-amidoamine linked cationic surfactants bearing a double tail were synthesized. Their chemical structures were interpreted with FTIR, 1H and 13C NMR spectroscopy. These surfactants consist of hydrophobes that may be obtained from sustainable resources. The objective was to synthesize a double tailed amidoamine having two functional groups in the structure and to investigate the effect of these groups on the interfacial as well as physical properties of the surfactants. The interfacial properties of the surfactants were determined using tensiometry, conductometry measurements and dye solubilization techniques. The synthesized surfactants have been found to exhibit quite low CMC in comparison with conventional surfactants of similar structure. The effect of sodium chloride on their surface properties was also studied. They were found to possess good and stable foaming ability and wettability. All the synthesized surfactants delivered appreciable antimicrobial activity against three tested microorganisms, Staphylococcus aureus and Escherichia coli.
Mixed Micelle Properties of Anionic Dimeric Surfactants with Anionic, Cationic, and Nonionic Surfactants
Authors: Kumar Naveen , Tyagi Rashmi
Published: February 2023

Herein, we have investigated the mixed micellar behavior of carboxylate anionic dimeric surfactants (CAD12 and CAD16) with commercial surfactants; anionic type i.e., sodium dodecyl sulfate, cationic i.e., cetyltrimethylammonium bromide and nonionic i.e., polyethylene glycol p-(1,1,3,3-tetramethylbutyl)-phenyl ether. The CMC values of mixed surfactants obtained from conductivity data decrease with a mole fraction of dimeric surfactants. The micellar characteristics (ideal CMC) and mutual interaction parameters (β) have been computed with the aid of theoretical models proposed by Clint, and Rubingh. In addition to this, thermodynamic parameters of micellization like 0 ΔG0mic, ΔH0mic, and ΔS0mic were evaluated and discussed.
COMPARATIVE CHARACTERISTICS OF THE DENSITY OF PERICULPAR DENTIN IN PERMANENT INTACT TEETH IN HEALTHY CHILDREN AND IN CHILDREN WITH OSTEOGENESIS IMPERFECTA
Authors: Tsymlyanskaya Viktoria , Shevchenko Maksim , Kisel'nikova Larisa , Lezhnev Dmitry , Petrovskaya Viktoria
Published: February 2023

The article presents the results of studying the degree of mineralization of the peripulpal dentin in healthy children and in children with osteogenesis imperfecta according to the data of cone beam computed tomography. In teeth with malformations of heavy tissue tissues, in particular with imperfect osteogenesis, pathological changes are noted in the special enamel and dentin involved in teeth and root canals. The study of the observed characteristics of the distribution of peripulpal dentin in dangerous intact teeth and teeth with malformations of hard dental tissues is of great interest.
Subject. Of the study is the degree of mineralization of the peripulpal dentin in permanent intact teeth in healthy children and in children with osteogenesis imperfecta.
Objectives. The degree of mineralization of periculpar dentin in children with osteogenesis imperfecta and in healthy peers in permanent intact teeth according to cone-beam computed tomography.
Methodology. The study was performed at the Department of Pediatric Dentistry and at the Department of Radiation Diagnostics of the Moscow State Medical University named after A.I. Evdokimov in the Department of X-ray and Radiation Diagnostics of the CCCHLPHIS Clinic of the Moscow State Medical University named after A.I. Evdokimov. The study involved 22 patients aged 7 to 14 years.
Results. In the group of children with imperfect osteogenesis in permanent molars with completed root formation, obliteration of the tooth cavity and wide root canals are noted. In the group of healthy children with permanent intact molars, no expansion of the tooth cavity and root canals was noted, no signs of root canal obliteration were detected. The average density of dentin in permanent molars in the group of healthy children is significantly higher than in children suffering from osteogenesis imperfecta.
Conclusions. Cone-beam computed tomography is an objective method of visualizing the teeth of both jaws, which allows with minimal radiation load and high accuracy to determine the density of periculpar dentin in permanent teeth in children in one study. Pronounced violations of the mineralization of hard tissues of teeth in children with osteogenesis imperfecta and require further study as the child grows up at the stages of dental rehabilitation.
SOME FEATURES OF THE CONDITION OF HARD TISSUES OF TEETH AND PERIODONTAL IN PATIENTS WITH INFLAMMATORY BOWEL DISEASES LIVING IN THE REPUBLIC OF BASHKORTOSTAN
Authors: Yunusova Rita , Usmanova Irina , Gerasimova Larisa , Ishmukhametova Amina , Lakman Irina , Akopyan Anait , Statseva Elena
Published: February 2023

The work presents the results of assessing the spread of pathology of hard tissues of teeth and periodontal in patients with chronic inflammatory bowel diseases (IBD). Objective. Assessment of the intensity and spread of pathology of dental hard tissues and inflammatory periodontal diseases in patients with Crohn's disease (CD) and chronic ulcerative colitis (CUC). Materials and methods. A comprehensive clinical and dental examination of 70 patients with CD and CUC was carried out. The complex of dental examination included the analysis of complaints, anamnesis, assessment of the condition of hard tissues of teeth, periodontal tissues. Assessment of the intensity level of nociceptive pain was carried out using a visual analog scale (VAS). Results and discussion. As a result of the clinical examination, a high prevalence of caries (K02) was revealed in CD and CUC, respectively, in 97.2% and 91.4% of cases, high and very high intensity of the carious process according to the CP index ≥ 10. With CD, the symptom of hyperesthesia, increased erasure of mixed teeth and wedge-shaped defects were most often observed in 100, 77.14 and 60.0% of cases, in 68.57% chronic periodontitis prevails (K05.3), with CD, the symptom of hyperesthesia (K03.80) and increased tooth erasure (K03.0) were 1.2 times less common) (p < 0.05), chronic gingivitis prevails in 62.85% (K05.10). The level of intensity of the pain symptom for patients with CD and CUC corresponds to the VAS scale from moderate to significant (p < 0.001). Results. As a result of a comprehensive dental examination of patients with CD and CUC, a high prevalence and intensity of caries and non-carious dental hard tissue lesions, inflammatory periodontal diseases, the level of dental care in persons with CD and CUC is insufficient. Conclusion. The connection of dental status with clinical manifestations of chronic inflammatory bowel diseases is beyond doubt. The ambiguity of the etiology and pathogenesis of CD and CUC as well as the significant similarity of their clinical manifestations, dictate the need for an integrated approach to the development of methods for diagnosing pathology of hard tissues of teeth and periodontal and assessing their clinical features.
The main dental indicators of children in Ekaterinburg and the Sverdlovsk region
Authors: Ioshenko Evgeniy , Ivanova Elena , Vorozhcova Lyudmila , Portnyagin Aleksey , Brusnitsyna Elena , Zakirov Taras , Ozhgihina Natalia , Shishmareva Anastasiya , Bimbas Evgeniya
Published: February 2023

The relevance of the problem of dental morbidity in children is obvious. In 2022, an epidemiological survey of the main dental diseases of the child population was conducted according to the WHO methodology in Ekaterinburg and the Sverdlovsk region in key groups of 3, 6, 12 and 15 years old. The epidemiological survey involved 756 children in six settlements of the region. The registration of the oral cavity condition was carried out using the "Maps for assessing the dental status of children" recommended by the World Health Organization (2013). Informed consent was obtained from parents and guardians to participate in the survey. Statistical processing of the results was carried out in the Statistica 10 program. In Yekaterinburg and the Sverdlovsk region, dental caries and inflammatory periodontal diseases remain the most common pathology in children. The prevalence of caries in 3, 6, 12, 15-year-olds was 34,2%, 80%, 20%, 86%, 96% accordingly , at an intensity of 2,3±0,5; 4,9±0,2; 4,59±0,3; 6,5±0,4. Signs of periodontal inflammation were detected among 12-year-olds in Yekaterinburg in 35.2% children, in the region - 38.1% of children. Among 15-year-olds, this indicator was 24.0% and 48.8%. These indicators increased with age. The prevalence of enamel hypoplasia in the main key group of 12-year-olds in Ekaterinburg was 8%, in the region – 12,9%. 90% of children need fissure sealing of permanent molars. In comparison with the previously conducted national epidemiological surveys of 2008 and 2015, there is an unfavorable dynamics and deterioration of the main indicators of dental morbidity. The epidemiological survey conducted in Ekaterinburg and the cities of the Sverdlovsk region is the justification for the development and implementation of a regional program for the prevention of dental diseases.
Relationship of Vitamin B12 and Vitamin D with IL-4, IL-10, TNF Beta in Obese Patients
Authors: GÜLBAY Gonca , KAYA Yasemin
Published: February 2023

Objective: We aimed to investigate the relationship of vitamin B12 and vitamin D with IL-4, IL-10 and TNF-Beta in obese patients. Methods: Serum IL-4, IL-10 and TNF-Beta levels were measured using kits based on the enzyme-linked immunosorbent assay (ELISA) principle. Results: The IL-10 level was found to be significantly lower in the low vitamin D group (p= 0.039). When vitamin B12 normal, vitamin B12 low and control groups were compared, a statistical difference was found between the groups in terms of IL-10 (p=0.002). As a result of post hoc analysis, the IL-10 level was found to be significantly lower in the vitamin B12 low group than in the vitamin B12 normal group (0.04). At the same time, vitamin B12 was statistically higher in the normal group (obesity positive) than in the control group (non-obese vit B12 normal) (p=0.001). A positive correlation was found between vitamin B12 and IL-10 (r= 0.203 p= 0.058). Conclusion: It has been shown that low levels of vitamin D and vitamin B12 in obese patients cause low levels of IL-10. It was also found that obesity caused an increase in IL-10 levels. No relationship was found between IL-4 and TNF-Beta and vitamin D and vitamin B12. Longer follow-up and studies in larger case populations are needed to better understand the effects of vitamin B12 and vitamin D on IL-4, IL-10 and TNF-Beta levels in obese patients.
Nie słyszę, a może słyszę więcej Projekt dźwiękowy Katarzyny Michalak i Magdaleny Świerczyńskiej-Dolot
Authors: Sygizman Kinga
Published: February 2023

W marcu 2020 roku Katarzyna Michalak i Magdalena Świerczyńska-Dolot rozpoczęły pracę nad projektem Nie słyszę, który stał się dźwiękową opowieścią o tym, jakiś dźwięków słuchaczom zabrakło w czasie kwarantanny i co to zmieniło, a jakie odgłosy pojawiły się w zamian. Z nadesłanych opowieści stworzyły reportaż radiowy. Artykuł jest omówieniem projektu, zarówno w postaci mininarracji zamieszczanych na blogu, jak i powstałego z nich reportażu radiowego. Przedstawia tematykę Nie słyszę, a także formalne rozwiązania zastosowane w reportażu dla uwypuklenia danych treści. Analiza projektu wpisana została w trzy perspektywy badawcze: rozważania na temat artystycznych gatunków radiowych, pejzażu dźwiękowego i filozofii braku. Artykuł podkreśla oryginalność pomysłu audialnego i ukazuje go jako element w dyskursie na temat roli mediów czasów pierwszego etapu pandemii.
History of Taekwondo Federation in Korea: Women and Industry Federation
Authors:   The World Society of Taekwondo Culture, Lee Chung-Young
Published: February 2023

This study specifically examines the development history of Women's Federations and Industry Federations among the five federations that have had a significant impact on the development of Taekwondo. This study was conducted with the goal of finding out through this and leaving a documentary trace on the development history of Taekwondo. Through the study, the following results were confirmed. First, the establishment of the Korean Women's Taekwondo Federation provided an opportunity to have a wider perspective on women's sports participation in Korea, and based on the establishment of the Women's Federation, it served as an opportunity for further development of Korean Women's Taekwondo. Second, the establishment of the Korea Industry Taekwondo Federation was established to help Taekwondo players continue their activities after graduating from college and discharged from the military. This is thought to be a stepping stone for diversification of the age group of Taekwondo players.
The Effect of Academic Stress on School Dropout of Chinese Physical Education Major University Students: The Mediating Effect of Social Support
Authors:   The World Society of Taekwondo Culture, Guo Qianronga , Huh Jinyoung
Published: February 2023

The purpose of this study is to verify the effect of academic stress and social support on school dropout intention of Chinese physical education major students and to investigate the mediating effect of social support. Therefore, the convenient sampling method was used to questionnaire survey. For data processing, frequency analysis, reliability, and correlation analysis were performed through SPSS 23.0, and confirmatory factor analysis, measurement model verification, structural model verification, and mediating effects were performed using AMOS 23.0. The following results were derived. Academic stress had a positive (+) effect on school dropout intention and social support. Social support had a negative (-) effect on school dropout intention. It was found that there was a partial mediating effect of social support in the relationship between academic stress and school dropout intention.
Determination of First Object Relations and Emotion Regulation Difficulties in Borderline Personality Disorder with Objective and Projective Methods
Authors: FARAJİ Haydeh , MUHTAR Dr. Öğretmen. Üyesi Hatice Nevzat , TEZCAN Ahmet Ertan
Published: February 2023

Evaluation of the disorders in the personality organization of the individual is only possible by examining the object relations functions, and it is known that the elimination of emotion regulation difficulties (ERD) has a central role in the treatment of borderline personality disorder (BPD). Therefore, this study, in which objective and projective methods were used together, was designed to determine the ERD of BPD patients and the relationship between the patients' object relations and emotion regulation difficulties. It is thought that the results of the study can be useful in the psychotherapy processes of BPD patients. For this purpose, the Sociodemographic Data Form, Rorschach Test, and Emotion Regulation Difficulty Scale developed by the researchers were applied to 37 individuals diagnosed with Borderline Personality Disorder according to DSM-5 criteria and 37 individuals who did not have any psychiatric diagnosis as a result of their psychiatric examination by a psychiatrist. As a result of the study, it was determined that there was a significant relationship between BPD and ERD, and this relationship could be determined through the Rorschach test, and it was determined that BPD constituted 55% of the variance of ERD. ERD, which can have significant disruptive effects on the lives of borderline patients, was associated with the patients' lack of satisfaction and inclusion in their relations with their first object, which is usually their parents, and it was determined negative qualities of first objects accounted for 23% of the variance of difficulty in emotion regulation. It is thought that the results of the study may contribute to the acceleration of the solution of interpersonal problems, which have a close relationship with ERD, of the patients and the standardization of the Rorschach Test.
HUBUNGAN ANTARA CONFUSED IDENTITY DENGAN PERILAKU AGRESIF REMAJA PADA SISWA SMP NEGERI 22 KELAS VII PALEMBANG
Authors: Siswoyo Siswoyo , Yuliansyah Yuliansyah
Published: February 2023

The purpose of this study was to determine whether there is relationship identity confused with aggressive behavior of adolescents Junior High School (SMP) 22 countries Palembang class VII. While the research hypothesis is that there is a positive relationship between identity confused with aggressive behavior of teenagers in SMP 22 countries Palembang.The variables of this study was confused identity and adolescent aggressive behavior. The population in this study are students (SMP) 22 countries Palembang totaling 270 students, the number of samples taken 45 students were determined using ramdon Sampling. Be Used collection instruments in this research is scale and scale identity confused adolescent aggressive behavior.Methods of data analysis using Pearson Product Moment of Pearson. Based on this analysis, showed no significant positive correlation between identity confused with aggressive behavior of teenagers at high school students (SMP) 22 countries Palembang with a correlation coefficient of 0.916 with a significance level by 0.05. That is, the higher the confused identity, the higher the aggressive behavior in adolescence.
HUBUNGAN ANTARA RELIGIUSITAS DENGAN KECEMASAN AKADEMIK PADA SISWA MADRASAH ALIYAH NEGERI
Authors: Ukhtia Fitri , Reza Iredho Fani , Zaharuddin Zaharuddin
Published: February 2023

Students often experience anxiety at the moment are in academic situations. This study examined the  correlation  between  religiosity  and  academic  anxiety  in  students  MAN  in  one  of  the  cities  of Palembang. The independent variables in this study are religiosity, while the dependent variable is the  academic  anxiety.  The  hypothesis  put  forward  is  no  relationship  between  religiosity  and academic anxiety in students. The sampling technique in this study using a random cluster sampling technique which produces 319 students as respondents. Data collection methods used in this study a scale  of  religiosity  that  is  made  by  researchers  using  the  dimensions  of  religiosity  based  on  the opinions  Jamaluddin  Ancok  and  Fuad  Nashori  Suroso  consisting  of  five  dimensions.  Then  the anxiety scale made by the academic researchers used a Hamilton anxiety symptoms based on the opinion  that  consists  of  14  symptoms.  Data  analysis  methods  used  to  test  the  hypothesis  of  this research  is  simple  regression  analysis  that  generates  a  correlation  coefficient  of  p  =  0.000  (p <0.05), which showed a negative correlation between religiosity and academic anxiety in students. The results of the donations given to anxiety academic religiosity of 16.8% and the rest influenced by other factors not disclosed in this study.