bluuebunny/crossref_metadata_2025 huggingface dataset:
Marketing researches are the tools for competitiveness management of the enterprise
Authors: Horodetskyi Mykola
Published: January 2020

Purpose. The aim of the study is the research of theoretical and practical recommendations on marketing researches for formation of tools for competitiveness management of the enterprise.

Methodology of research. The methodological basis of the study is the dialectical method of cognition, applied in the process of researching the problems of managing marketing research of the enterprise. The following methods are used in solving the tasks to achieve the goals: abstract and logical (to clarify the interpretations of the categorical tools of the research topic), the analysis and synthesis method and the method of scientific abstraction – to define the concept of “marketing research”; structural and functional method and the method of analysis and comparison – for the nature and purpose of marketing research; system analysis method, historical and logical approach – to represent the evolution of marketing researches.

Findings. The author has proposed a mechanism for the formation of competitive positioning for an enterprise, which is based on the process of marketing research management. The mechanism is based on a systematic research activity that answers the question of what forms a favourable opinion of consumers and determines its choice over competitors.

Originality. A benchmarking approach is proposed to optimize the process of managing marketing research for the enterprise. It allows the company to navigate in a complex and changing market environment and in the market for customer service and identify appropriate directions for creating competitive advantages.

Practical value. The results of the study can be used in the practical activities of car service enterprises to conduct more informed marketing researches.

Key words: marketing researches; competitiveness; management process; consumers; market environment; marketing information; management tools.
In silico Analysis of 1,4-butanediol Heterologous Pathway Impact on Escherichia coli Metabolism
Authors: Bodor Zsolt , Tompos Lehel , Nechifor Aurelia Cristina , Bodor Katalin
Published: January 2020

The bio-based synthesis of 1,4-butanediol (BDO), a key compound in many industries, has recently been achieved in Escherichia coli, however the yield even in glucose was far below the theoretical maximum. Furthermore, the impact of the BDO pathway on cell metabolism is yet to be discovered. The main objective of this study was to in silico improve and analyze the production potential of BDO on glucose and glycerol and evaluate the interaction between native and non-native pathways for wild-type and mutant strains using a simple biosynthetic pathway. The maximum production potential and changes in metabolic fluxes were simulated by different objective functions (biomass and BDO) and the reactions with highest differences were identified under different environmental conditions. Considering the outcomes 80% of the reactions with significant flux change were identical for all conditions simulated. Flux variability analysis was carried out to decipher the variation of fluxes and flux span changes (SC) were calculated. To further analyse the reactions with SC over 1 mmol gDW-1h-1 and to calculate the correlation coefficients for WT and mutant strains uniform random sampling was carried out. Most important variations in correlation patterns were observed for reactions in the mutant model. On the other hand, the addition, elimination and optimization of different pathways significantly affected the pairwise correlation patterns as well as the entire solution space of the network.
Effects of Liming and Fertilization on the Dehydrogenase and Catalase Activities
Authors: Samuel Alina Dora , Bungau Simona , Fodor Ilona Katalin , Tit Delia Mirela , Blidar Cristian Felix , David Ana Teodora , Melinte (Frunzulica) Carmen Elena
Published: January 2020

In this paper we provide new data about the soil enzyme activity as a biological process, which is an indicator for impacts of factorial combinations of lime and fertilizers applications. Five plots divided into fifteen subplots were sampled for determination of the enzymatic indicators of soil quality, based on the actual and potential dehydrogenase and catalase activities. The research revealed that limed soil samples, in comparison with unlimed ones, resulted in significantly higher soil enzymatic activities (p[0.05) in the upper (0-20 cm), while in the deeper (20-40 cm) layer, only catalase activity was significantly higher (at least at p[0.02). Mineral fertilization, in comparison with its farmyard manuring, led to an insignificant increase in each of the three enzymatic activities determined, excepting catalase activity which was significantly higher (0.05]p]0.02) in the 0-20 cm layer. Based on the absolute values of the enzymatic activities, the enzymatic indicators of soil quality (EISQ) were calculated. The mineral NPK-fertilization and low dose of lime in the 0-20 cm layer, and mineral NP-fertilization and low dose of lime in the 20-40 cm layer proved to be the best variants of fertilization. The enzymatic indicators of soil quality in these variants reached the highest values: EISQ=0.821 and EISQ=0.889, respectively, indicating the presence of high enzymatic activities. It should be emphasized that a balanced application of lime, mineral fertilizers and farmyard manure leads to the formation of favorable conditions for the development of microorganisms, growth of plants and for an intense and lasting enzymatic activity.
Iodometric Quantitative Analysis Method of Ascorbic Acid in Tablets
Authors: Georgescu Costinela Valerica , Gavat Cristian Catalin , Voinescu Doina Carina
Published: January 2020

Ascorbic acid is a water-soluble vitamin provided with strong antioxidant action, that fulfills an important immune protective role of the body against infections and prevents various cancers appearance. The main goal of this study was to exactly quantify pure ascorbic acid in tablets of two pharmaceuticals. Proposed objective consisted in improvement and application of a iodometric titration method in ascorbic acid quantitative analysis. Ascorbic acid content per tablet in both studied pharmaceuticals was 173.84 mg, very close to official stated amount of active substance (180 mg). Allowed percentage deviation from declared content of pure ascorbic acid was only 3.42 %, below maximum value of � 5 % imposed by Romanian Pharmacopoeia 10-th Edition, according to European and International standards. Statistical analysis confirmed experimental obtained results and revealed low Standard Error value SE = 0.214476, which has fallen within normal limits. Confidence Level value (95.0 %) = 0.551328 and Standard Deviation SD = 0.525357. were within normal range of values. Relative Standard Deviation (Coefficient of variation or homogeneity) RSD = 26.268% was found below maximum range of accepted values (30-35%). P value = 7.44. 10-6 was located within normal limits, P [ 0.001, so the experimental obtained results has shown highest statistical significance. Thus, studied titration method can be successfully used in quantitative analysis of ascorbic acid from different samples.
Synthesis, Characterization, Molecular Docking and Enzyme Inhibition Studies of Some Novel Enaminone Derivatives and Their Complexes with Cu(II), Cd(II) and Co(II) Ions
Authors: Huma Rahila , Mahmud Tariq , Mitu Liviu , Ashraf Muhammad , Iqbal Ambar , Iftikhar Kiran , Hayat Anum
Published: January 2020

Two new enaminone ligands, 3-chloro-4-{(4-chlorophenyl)amino}pent-3-en-2-one (Ac-PCA), 4-(benzylamino)-3-chloropent-3-en-2-one (Ac-BA) and their metal complexes with transition metal ions [Cu(II), Cd(II) and Co(II)] were prepared and subsequently characterized by FTIR, ICP-AES, UV-Vis, TGA, 1H NMR, 13C NMR and FAB-MS. These newly synthesized compounds were further investigated for anti-acetylcholinesterase (AChE) and anti-urease activities. The (Ac-BA)Cu(II) complex exhibited good anti-AChE while (Ac-BA)2Co(II) complex was potent against anti-urease activities. Other ligands and complexes showed poor to no enzyme inhibitory activities. The synthesized compounds were docked inside acetylcholinesterase enzymes to determine their putative binding mode.
Evaluation of Heavy Metals and Organic Compounds in Water Samples Collected from Various Sources from Republic of Moldova and Romania
Authors: Untila Carolina , Caraman Mihail , Nedeff Valentin , Barsan Narcis , Sandu Ion , Chitimus Alexandra Dana , Cretu Vasile Valentin , Tomozei Claudia , Sandu Andrei Victor
Published: January 2020

This work presents the study and determination of composition of natural water samples collected from five different types of water sources from Republic of Moldova and Romania: river, lake, spring, fountain and rain. The purpose of this study was to establish whether some of the heavy metals and organic compounds with impact on population health are present in drinking water samples and if their presence falls within the set limits by national regulations. The analysis has been performed using VIS spectrophotometer with RFID technology and individual parameter express cuvette tests for water analysis which allowed ensuring high accuracy of the measurements. Thus, over limits high rates of Pb2+ and Ni2+ have been found in all samples. A high concentration of F- was determined from fountain water - 2.92 mg/L and of Fe from river - 0.701 mg/L, which is twice than admissible values. The lowest concentration has been measured in the rainwater.
Galvanic Corrosion Behaviour of Phosphate Nodular Cast Iron in Different Types of Residual Waters and Couplings
Authors: Nejneru Carmen , Perju Manuela Cristina , Burduhos Nergis Dumitru Doru , Sandu Andrei Victor , Bejinariu Costica
Published: January 2020

The aim of this paper is to analyze the corrosion process that occurs in galvanic couplings of different alloys. The study focuses on materials that can come into contact in submersible pumps used by water treatment plants. Because, the rotor, one of the pump main components must possess high chemical and mechanical properties, nodular cast iron is usually used. Therefore, this is exposed in the same environment with different types of materials, such as aluminum, copper, bronze, grey cast iron, low alloy steel or stainless steel from which other components are made. The tests have been performed in three types of residual waters with neutral, acidic and basic pH. According to this study, the nodular cast iron galvanic corrosion resistance is highly improved by the phosphate layer deposited on its surface.
Thioctic Acid and Vitamin B Complex Improves Clinical Sings in Diabetic Peripheral Neuropathy
Authors: Rotaru Andreea , Albu Carmen Valeria , Tudorascu Diana Rodica , Catalin Bogdan , Gheonea Mihaela , Udristoiu Ion , Iancau Maria
Published: January 2020

Diabetic neuropathy is the most common cause of neuropathy worldwide and it is estimated to affect about half of people with diabetes. The goal of our study is to compare the effectiveness of thioctic acid treatment alone versus the efficacy of thioctic acid plus vitamin B complex in patients with diabetic peripheral polyneuropathy (DPN). We conducted a prospective, observational study staring from October 2017 to December 2018, in which we included 56 DPN patients. Depending on the Michigan neuropathic screening instrument (MNSI) we divided the patients into two subgroups: patients with MNSI [7 and patients whose MNSI did not decrease sufficiently during the therapeutic protocol. 36 patients (64.2%) of the total patients enrolled in the study had an MNSI [7 at one of the follow-up meetings. These patients were also divided according to the therapeutic protocol applied in a group of patients who were treated with only thioctic acid (TA group) and in a group of patients who were treated with thioctic acid plus vitamin B complex (TA + B group). We noticed a greater proportion of patients who had a MNSI [7 in the TA + B group. This study revealed that the treatment of peripheral diabetic neuropathy with thioctic acid plus Vitamin B complex compared to thioctic acid alone was superior in terms of improving clinical features.
Metabolic Analysis in Women with Polycystic Ovary Highlight Specific Biomarkers of Insulin Resistance
Authors: Vonica Camelia Larisa , Fodor Adriana , Roman Gabriela , Mureasan Andrada Alina , Farcas Anca Daniela , Inceu Georgeta Victoria , Rusu Adriana , Georgescu Carmen Emanuela
Published: January 2020

The aim of the paper is to detect insulin resistance (IR) biomarkers via metabolomics. It is important to understand the PCOS pathophysiology, diagnosis measures and, subsequently, to improve treatment type and time of IR in PCOS. In most cases, almost half of the women with PCOS have IR which is triggered by inflammation, glucotoxicity and lipotoxicity. In this work was conducted a systematic review of all the papers that used metabolomics for detecting IR biomarkers in PCOS women. The exclusion criteria were: reviews, study population with women bellow 18 years of age, studies including animals and articles not in English, remaining 4 records. The results from the literature shown that phosphatidylcholines were decreased in IR PCOS women when compared to controls. Nonetheless, trans-2-hexenoylcoa, linoleic acid, leucine, myristic acid and palmitic acid regarding lipid metabolism and tyrosine, lysine, phenylalanine a-aminoadipic acid regarding amino acid metabolism were also corelated to IR in PCOS women when compared with healthy or IR controls. Lactate was the only increased metabolite related to glucose metabolism in IR PCOS women. Metabolic alteration in PCOS women with IR when are compared with controls and results that those are brought by both PCOS and IR. Lyso-phosphatidylcholine have an important pro-inflammatory and altered insulin signaling effect, both alterations being considered hallmarks of PCOS women. Serine hyperphosphorylation of the receptor accentuates IR by decreasing the signaling of insulin receptor. Moreover, high levels of lactate correlated with IR in PCOS women may indicate high muscle glycolysis, hepatic glucose production and peripheral glucose uptake. IR biomarkers in PCOS women were evidenced by metabolomics technique.
Pulmonary Complications in Measles 2016-2018
Authors: Nicolescu Narcisa Daniela , Musta Virgil Filaret , Laza Ruxandra , Marinescu Adelina Raluca , Birlad Andreea Mihaela , Lazureanu Voichita
Published: January 2020

Measles is a viral disease that we have chosen to talk about because of the progressively increasing number of cases, the respiratory complications that progress toward respiratory failure in children and because of the costs that could be lowerd if vaccinations were carried out according to the proposed Schedule by the Ministry of Health. Our research was conducted during 05.2016-31.12.2018 analyzed according to several criteria (age group, sex, personal history, complications, evolution, treatment, etc.). There are 3 particular clinical cases. From the pathophysiological point of view, we consider the focus on respiratory complications to be useful, most complications being alveolar pneumonia in children under 2 years of age, reaching to acute respiratory failure. Can we prevent this?
Vitamin D(25-OH-cholecalciferol) in Cystic Fibrosis and the Relations with Cholesterol and Proteins
Authors: Ciuca Ioana Mihaiela , Pop Liviu Laurentiu , Dediu Mihaela , Tanasescu Sonia Aniela , Ardelean Florina , Iovanescu Gheorghe , Boeriu Estera , Vlad Cristina Daliborca , Marc Monica Steluta , Guta Bogdan Almajan
Published: January 2020

Study aimed to assess the level of 25-OH-cholecalciferol(vitamin D) and the relation with cholesterol, proteins and glycaemia levels in patients with cystic fibrosis. 58 patients underwent for the annual evaluations and were tested for vitamin D deficiency, as the centre�s protocol requires, besides dosage of cholesterol, glycaemia and proteins levels. Serum levels of 25-hydroxycholecalciferol were compared to levels of cholesterol, proteins and glycaemia, using Pearson correlation and logistic regression. The average value of 25-OH-cholecalciferol was 22,9 ng/mL, suggesting an important deficiency and different stages of 25-OH-cholecalciferol deficiency was found in the majority of patients. Nor a positive correlation neither negative relationship was found between vitamin D and cholesterol (r=0,23), glycaemia or proteins level. Vitamin D levels are not related to cholesterol or proteins in our study. Although cystic fibrosis is characterised by liposoluble vitamins deficiency and lipids impaired digestion, other factors influence the seric levels of vitamin D and lipids.
Rehabilitation and Creation of Favorable Conditions for the Improvement of the Comfort and Quality of Acrylates Used in the Sphere of Removable Dentures
Authors: Feier Ramona Diana , Topor Gabi , Anghel Lucretia , Aungurencei Andra Elena , Negraia Magdalena Rusu
Published: January 2020

The total acrylic denture is a conventional prosthesis method in case of total edentation, when there are 1-2 remaining teeth on the arch. The purpose of these dentures is to recreate functionality and improve the esthetic condition, being the optimum solution for improving the life of patients who have lost their natural teeth. Acrylic resins have been used in dentistry since 1937, a date which marked the progressive and final replacement of vulcanized rubber (vulcanite). From a chemical point of view, acrylates are macromolecular resins derived from acrylic acid, obtained by polymerization of several substances which derive from the acrylic acid, methacrylic acid and the esters of these acids. Metallic inserts can be added in the structure of the plastic masses, under the form of wires, bars, grids, nets. Bar and wire reinforcement has been proved efficient in improving the mechanical properties of the bases of total dentures, compared to grids, which failed to constantly ensure significant improvement. The position and thickness of reinforcement inside the plastic mass hugely influences the efficiency of reinforcement; the reinforcement must be placed perpendicularly on the anticipated fracture line. Our study was carried out in the Dental Clinic and comprises a number of 17 patients. The lot included patients aged between 50 and 85. Clinical observations have been made on fracture cases of acrylic bases, followed by the analysis and assessment of certain clinical aspects with a high risk of fracture (maxillary/mandible, with a median/paramedian line, etc.) which, associated, increase the risk of fracture even more. Clinical observations have shown the presence of fracture risk in acrylic dentures, showing the necessity of a correct design and production of removable dentures but also of using inserts.
Serum Homocysteine and Reactive Species Levels in Fragility Fractures of the Pelvis
Authors: Filip Alexandru , Badulescu Oana Viola , Sirbu Paul Dan , Cojocaru Elena , Filip Nina , Puha Gabriela , Trandafir Laura , Iancu Cristina , Trandafirescu Mioara Florentina , Alexa Ovidiu
Published: January 2020

Although there are studies showing the link between homocysteine and bone quality, the relationship remains controversial. The purpose of the study was to investigate homocysteine levels in patients with fragility fractures of the pelvis and their association with serum Total Antioxidant Status.The study included a group of 60 patients, aged ]65years, with pelvic fragility fractures and osteoporosis admitted in our trauma department between January 2015 and January 2018 and a control group of 30 patients, aged ]65years without fragility fractures or osteoporosis.The total antioxidant status (TAS) and homocysteine (Hcy) concentrations were determined in serum of all the patients. TAS levels had a significantly lower values in the group with pelvic fragility fractures compared with the control group (p[0.001).We noticed a significant higher mean of Hcy levels (p[0.001) in patients with pelvic fragility fractures compared with the control group. As conclusion this study shows that patients with fragility fractures of the pelvis have moderately elevated levels of homocysteine and reduced serum Total Antioxidant Status.
The Evaluation of Hemoglobin Fluctuation After Percutaneous Nephrolithotomy
Authors: Martha Orsolya , Hodade Daniel Porav , Scarneciu Ioan , Ghirca Veronica , Maxim Laurian , Laculiceanu Alexandru , Cobelschi Calin Pavel , Scarneciu Camelia , Gherghiceanu Florentina , Todea Moga Ciprian
Published: January 2020

The aim of this study was to evaluate the fluctuation of haemoglobin value after performing percutaneous nephrolithotomy (PCNL) in the treatment of kidney stones. We conducted a retrospective study and we included 327 patients who underwent PCNL for renal lithiasis. We evaluated the risk factors for bleeding: location of stones, complexity of lithiasis, length of postoperative hospitalization days, variation of post-operative laboratory constants (haemoglobin, haematocrit). Patients were divided into two age groups: group A (patients under 70 years old) and group B (patients over 70 years). Gender distribution was: 171 female and 156 male. In most of the cases, the stones were located in the renal pelvis (133 cases), multiple lithiasis (105 cases) and staghorn stones (48 cases). There was no statistical difference between the patient�s groups concerning the decrease of post-operative Hgb concentration and complexity of the litiasis, p = 0.10. The average length of post-operative hospitalisation was 3.91 +/- 1.78 SD days in patients who did not have significant hemorrhage and 6.40 +/- 2.35 SD days in patients with intra- and post-operative haemorrhage. The postoperative Hgb levels correlated with post-operative days of hospitalization in elderly patients (rr = -0.44, p = 0.0001). Stone complexity, the size, number or localization of the stones, were not risk factors for the decrease of haemoglobin level after PCNL. Decreased postoperative haemoglobin values can led to increased number of hospitalization days.
Structural Characterization of ZnO and Al Doped ZnO Powders Synthesis in Aqueous Solutions
Authors: Topala Carmen Mihaela , Plaiasu Adriana Gabriela , Ducu Catalin Marian , Moga Sorin Georgian
Published: January 2020

Undoped and Al-doped ZnO (AZO) powders have been synthesized by hydrolytic and hydrothermal synthesis from Zn(NO3)2 , AlCl3 using KOH 1M concentraction like hydrolisis agent. The structural properties of prepared powders were studied using XRD and FTIR spectroscopy. Presence of aluminium in the hydrothermal powders is correlated with the presence of Zn-Al hydrotalcite like structure.
Study on the Influence of Free Radicals and Oxidative Stress on Peptic Ulcers
Authors: Balint Germaine Savoiu , Toth Emeric , Andoni Mihaiela , Demeter Ioan , Borza Claudia , Floroni Erwin , Pacurar Mariana , Ciobanu Virgil
Published: January 2020

It can be observed that oxidative stress initiates and aggravates many diseases, including peptic ulcers and gastric carcinoma. An increase in rat mucosal glandular lipid peroxidation (LPO) and superoxide dismutase (SOD) and a decrease in catalase (CAT) levels in gastric ulceration induced by cold retention stress were observed, whereas in patients with ulcerated clinical peptic and gastric carcinoma LPO serum is associated with a decrease in SOD and CAT. It was intended to determine the parameters of oxidative stress in the blood and brain in rats after induction of gastric ulcer, the effect of antioxidant treatment on these parameters and on the appearance of gastric ulcer, determination of correlation between oxidative stress and severity of gastric ulcer in rats and also evaluation of vascular endothelial function by in vitro studies in the organ bath, from rat aortic rings with gastric ulcer vs. normal and others under treatment vs. untreated.
The Association of Body Mass Index and Ki67 Values in Patients with Endometrial Carcinoma
Authors: Furau Alexandru , Craina Marius Lucian , Furau Cristian , Luca Tudor Constantin , Andor Bogdan Corneliu , Radu Daniela , Moleriu Lavinia Cristina , Bonte Diana Camelia , Toader Daniela Oana , Furau Gheorghe
Published: January 2020

Endometrial cancer begins in the layer of cells that form the lining (endometrium) of the uterus. Endometrial cancer is often detected at an early stage because it frequently produces abnormal vaginal bleeding, which prompts women to see their doctors. If endometrial cancer is discovered early, removing the uterus surgically often cures endometrial cancer. The study included all patients who had been evaluated for vaginal bleeding in Obstetrics and Gynecology Department of Clinical Emergency County Hospital, Timisoara between 2016-2018. Of the 195 cases of uterus scraping, 19 cases were labelled as malignant endometrial pathology. For the statistical analysis we calculated some descriptive statistics for the age parameter and the BMI (body mass index) parameter in our disease sample and we compared the BMI values to the BMI values from the control sample As well, we tested to see if there is an association between the Ki-67 values and the HER-2 / neu status in patients with or without endometrial carcinoma. In order to test the significance we applied a Mann -Whitney test, for a = 0.05 set as a confidence level. Unfortunately, in the case of our study group, type 1 endometrial cancers are found in only 5 cases, unlike other countries where most of endometrial cancers are diagnosed early (80% in the first stage) and the 5-year survival rate is about 95%. In any case, the 5-year survival rate is much lower if there is involvement of regional lymph nodes or distant metastasis (68% and 17%, respectively) - as in our case where all cases were classified as Stage III and IV. By running the statistical test we obtained extremely significant differences in the BMI of our patients (p[0.001), the diseased patients tend to have higher BMI values. As well, when we tested the possible association between the Ki-67 values and the HER-2 / neu status in our two groups (patients with or without endometrial carcinoma) we obtained extremely significant differences (p[0.001). The Ki-67 values are increasing proportionally with the carcinoma staging. An endometrial biopsy is the most commonly used test for endometrial cancer and is very accurate in postmenopausal women.
Biojet from Hydroconversion of Camelina Oil Mixed with Straight Run Gas Oil
Authors: Tepelus Alexandru , Rosca Paul , Dragomir Raluca
Published: January 2020

In the current research study camelina non edible oil (CO) was used as renewable feedstock for production of jet fuel by hydroconversion processes. The vegetable oil was mixed with straight run gas oil (SRGO) at 10, 15 and 20 % ratio. The hydrotreating experiments were carried out in micropilot plant flow reactor over NiMo/Al2O3 catalyst at 350oC and 380oC, 80 bar pressure 1h-1 and 1.5 h-1 liquid hourly space velocity (LHSV). The research focuses on the influence of the SRGO-CO ratio, temperature and LHSV on the yields and the physiochemical properties of the biojet (160-300oC) obtained. The hydrotreating reactions which occur during the process, produce 36-45% wt jet yields but bad flow properties due to the n-paraffins with 13-20 carbon atoms in molecules obtained from hydrogenation of vegetable oil. These characteristics can be corrected by hydroisomerisation. The results show that the hydrotreatment of CO and SRGO-CO mixtures are an alternative for biofuel production with characteristics similar to jet fuel.
Troilite (FeS) Oxidation in the Presence of a Newly Synthesized TRIS-based Base
Authors: Duinea Madalina Ionela , Carac Geta , Dabuleanu Irina Daniela , Petcu Mihaela Alexandra , Sarbu Laura Gabriela , Birsa Mihail Lucian , Chirita Paul
Published: January 2020

The effect of a newly synthesized TRIS-based Schiff base (XC) on the oxidative dissolution of FeS in air-equilibrated solutions with pH 2.26 and temperature of 27�C was investigated by Potentiodynamic polarization, Cyclic Voltammetry, Optical Microscopy and quantum chemical calculations. The XC concentration varied between 0 and 0.52 mM. It was observed that XC decreases the corrosion current densities of the oxidative dissolution of FeS. Our results indicate that the inhibitory effect of XC is due to its adsorption on the FeS surface.
In silico Docking Study of Some Coumarin Derivatives as Potential Inhibitors on Different Dengue Viral Proteins
Authors: Tataringa Gabriela , Sathyamurthy Balasubramanian , Sandu Ion , Zbancioc Ana Maria
Published: January 2020

In this study, the binding efficiency of 10 coumarin derivatives with some selected proteins from Dengue virus through in silico method was done. By virtual screening and docking results, we have found that the hybrid derivative between coumarin and isatin has the most convenient binding activity for the seven selected proteins.
Immunohistochemical Expression of Growth Hormone Secretagogue Receptor (GSH-R) of Adipose Tissue Macrophagesin Obese Bariatric Patients
Authors: Timofte Daniel , Mocanu Veronica , Eloae Florin Zugun , Hristov Ioana , Silivestru Cretu Iustina , Aursulesei Viviana , Balan Gheorghe G. , Ciuntu Bogdan Mihnea , Oboroceanu Teodor , Tiron Adrian , Costan Victor Vlad , Butcovan Doina
Published: January 2020

Obesity is a major cause of adipose tissue (AT) inflammation. Ghrelin (GHRL), through its growth hormone secretagogue receptor (GHS-R) present on adipose tissue macrophages (ATMs), could modulate AT inflammation.
Electrochemical Evaluation of Some Mg-Ca-Mn-Zr Biodegradable Alloys
Authors: Istrate Bogdan , Munteanu Corneliu , Chelariu Romeu , Mihai Dumitru , Cimpoesu Ramona , Ville Tudose Florin Sandu
Published: January 2020

Biodegradable magnesium alloys represent a class of materials with high properties that are used in a wide range of fields, such as medicine, aeronautics and automotive. Alloying the Mg-based alloys with small percentages of elements such as Ca, Mn and Zr can conduct to the obtaining of some materials that can be the basis for the development of orthopedic implants. Calcium contributes to the formation of the Mg2Ca lamellar compound, low concentrations of zirconium helps the microstructure refinement and corrosion resistance and the alloying with manganese leads to the increase of the mechanical characteristics.In this paper, the electrochemical behaviour of four biodegradable alloys from the Mg-Ca-Mn-Zr system was evaluated, with variable concentrations (0.5% -1%) of Mn, respectively Zr. Alloying the system with 1% of each element (Ca, Mn, Zr) led to the obtaining of the alloy with the highest corrosion resistance and the lowest degradation rate.
Peranan Gereja dalam Menghambat Laju Pertumbuhan Pemakai Narkoba
Authors: Simon Simon
Published: January 2020

Indonesia is a country that is fertile ground for drug trafficking carried out by domestic dealers and drug dealers internationally. The rise of drugs today causes victims to die every day. President Jokowi came to state that Indonesia was on the verge of a "drug emergency", because every day 50 people died. If in just one year it could reach 18,000 people die each year. Seeing these facts, of course the government appealed through the National Narcotics Agency (BNN) that this should not be left unnoticed because it would have an increasingly bad impact. This research aims to give an idea to the churches that the spread of drugs and the number of users is alarming in the midst of this nation. The method that the author uses in writing this article uses a qualitative method with a literature study approach. The role that can be demonstrated by the church in drug prevention by preaching the dangers of drugs in the pulpits, partnering with BNN institutions as the frontline in eradicating drugs, conducting visits to rehabilitation sites and optimizing the role of families as supervisors.

Indonesia merupakan salah satu negara yang menjadi lahan subur dalam peredaran narkoba yang dilakukan oleh para bandar dalam negeri maupun bandar narkoba secara internasional. Maraknya narkoba di masa kini menyebabkan adanya korban yang meninggal setiap hari. Presiden Jokowi pun sampai  menyatakan bahwa Indonesia telah berada pada ambang “darurat narkoba,” dikarenakan setiap harinya meninggal 50 orang. Bila dalam setahun saja  dapat mencapai 18. 000 orang meninggal setiap tahunnya.  Melihat fakta-fakta ini, tentunya pemerintah menghimbau melalui Badan Narkotika Nasional (BNN) mengemukan hal ini tidak boleh dibiarkan begitu saja karena akan semakin berdampak buruk. Penelitian ini bertujuan untuk memberikan gambaran kepada gereja-gereja bahwa penyebaran narkoba serta jumlah pemakainya sudah mengkuatirkan di tengah bangsa ini. Adapun metode yang penulis gunakan dalam penulisan artikel ini menggunakan metode kualitatif dengan pendekatan studi literatur. Peranan yang dapat ditunjukkan oleh gereja dalam pencegahan narkoba dengan mengkhotbahkan bahaya narkoba di mimbar-mimbar, bermitra dengan lembaga BNN sebagai garda terdepan pemberantas naskoba, mengadakan kunjungan ketempat rehabilitasi dan mengoptimalkan peran keluarga sebagai pengawas.
RANCANGAN MOBILE APPLICATION UNTUK MENGELOLA DAN MENYEDIAKAN PEKERJAAN
Authors: Heripracoyo Sulistyo
Published: January 2020

Kebutuhan informasi masyarakat telah tumbuh, terutama permintaan untuk informasi tersebut

sepenuhnya dapat diakses melalui berbagai perangkat mobile di mana saja dan kapan saja. Salah satu

kebutuhan informasi adalah informasi tentang lowongan pekerjaan. Tujuan dari penelitian ini adalah untuk

memetakan informasi lowongan pekerjaan dengan beberapa informasi tentang pekerjaan dan informasi tentang

lokasi perusahaan yang menyediakan pekerjaan tersebut ke dalam desain database dan aplikasi mobile.

Manfaatnya adalah masyarakat dapat menemukan informasi lowongan pekerjaan berdasarkan kriteria yang

diperlukan. Metode dalam penelitian ini adalah metode kuantitatif dengan observasi. Analisis perancangan

database dilakukan oleh tiga level ANSI-SPARC untuk perancangan basis data dan disertai dengan desain

antarmuka pengguna untuk aplikasi mobile berbasis platform Android. Hasil dari penelitian ini adalah model

aplikasi database yang dapat diimplementasikan dan diakses oleh publik untuk mencari informasi apa saja

tentang lowongan pekerjaan melalui aplikasi mobile. Hasil penelitian dapat mendukung tingkat yang dibutuhkan

pemerintah dalam mengimplementasikan kota pintar.
PERANCANGAN MASTER DATA MANAGEMENT PADA REGULATOR INSTITUSI FINANSIAL
Authors: Hartono Sugiharto
Published: January 2020

Regulator Institusi Finansial di Indonesia mengemban amanat dan wewenang untuk menyelenggarakan sistem pengaturan dan pengawasan yang terintegrasi terhadap keseluruhan kegiatan di pelaku Industri Jasa Keuangan (IJK). Tujuan penelitian ini adalah untuk menghasilkan single view data Akuntan dan Penilai, untuk melakukan migrasi data Akuntan dan Penilai yang ada pada excel ke sistem, dan dapat dijadikan pondasi dan langkah awal dalam penerapan MDM untuk sektor lainnya di Regulator Institusi Finansial. Metode yang digunakan dalam penelitian ini adalah studi literatur, studi lapangan (wawancara dan dokumentasi), serta menggunakan Object Oriented Analysis and Design. Solusi yang diberikan adalah dengan melakukan perancangan master data management agar tidak terjadi kesalahan serta mempercepat dalam pengambilan keputusan (dalam hal redudansi data pada profesi penunjang lainnya) dikarenakan media penyimpanan data masing masing profesi berbeda.
PERANCANGAN DAN IMPLEMENTASI GAME SIMULASI UNTUK MENGETAHUI NEUROTISME BERDASARKAN INTERNATIONAL PERSONALITY ITEM POOL
Authors: Satria Thomas Galih , Sudarma Hantze , Panggabean Francisco Maruli
Published: January 2020

International Personality Item Pool - Neuroticism, Extraversion & Openness (IPIP-NEO) merupakan sebuah tes kepribadian yang didasari atas teori Big Five Personality di mana tes tersebut berbentuk kuesioner. Tujuan dari penelitian ini adalah untuk merancang sebuah media alternatif dalam menggunakan IPIP-NEO khususnya bagian neurotisme ke dalam sebuah game simulasi. Masalah yang diangkat adalah tes kepribadian IPIP-NEO merupakan sebuah kuesioner yang tidak memberikan gambaran situasi akan pertanyaan yang ditanyakan kepada responden. Berdasarkan masalah yang ada, pengumpulan data berupa studi pustaka, kuesioner, dan wawancara kepada pakarnya, dapat dibuat kebutuhan pembuatan game. Hasil game kemudian dievaluasi menggunakan kuesioner yang ditujukan kepada sampel dari Non Probability Purposive Sampling.
SISTEM PENDUKUNG KEPUTUSAN PEMILIHAN “BEST AGENT” DENGAN METODE PROFILE MATCHING (GAP)
Authors: Budiyantara Agus , Maulana Brian Arif
Published: January 2020

Penilaian kinerja staff merupakan proses penilaian yang dilakukan untuk mengetahui staff yang berkualitas dan berdedikasi tinggi. Manajer memiliki pemasalahan untuk bisa mengevaluasi atas kinerja staff pada sebuah acara yang bertema “Change Agent” dan staff terbaik diberi nama “Best Agent”. Dikarenakan sistem penilaian secara manual dengan mengisi form nilai kemudian dijumlahkan dan diperoleh rata-ratanya. Aplikasi Sistem Pendukung Keputusan Pemilihan “Best Agent” metode Profile Matching merupakan sebuah aplikasi yang dirancang untuk memberikan sebuah alternatif keputusan yang akurat didasarkan pada data terkini dan dapat dipertanggungjawabkan, hal ini diharapkan dapat meningkatkan kualitas kinerja staff dan harapan besarnya adalah terbangunnya peningkatan kinerja yang baik sehingga meningkatkan kualitas SDM dan membawa nama baik institusi.

Kata kunci: Sistem Pendukung Keputusan, Manajemen Kinerja, Metode Profile Matching.

Staff performance appraisal is an appraisal process undertaken to find qualified and dedicated staff. Managers have problems to be able to evaluate staff performance at an event entitled "Change Agent" and the best staff is named "Best Agent". Due to the manual appraisal system by filling in the value form then adding up and obtaining the average. Decision Support System Approval Selection of "Best Agent" Profile Matching method is an application designed to provide an accurate decision alternative based on current and accountable data, it is expected to improve the quality of staff performance and the expectation of the magnitude is the establishment improvement in good performance so as to improve the quality of human resources and bring the institution's good name to both the scope of the Department and more broadly.

Keywords: Decision Support System, Performance Management, Profile Matching Method.
PENGARUH KUALITAS PELAYANAN, KUALITAS PRODUK DAN HARGA TERHADAP KEPUASAN KONSUMEN
Authors: Asti Eka , Ayuningtyas Eka
Published: January 2020

Business competition is getting tighter, making the producers are required to always think creatively and critically in developing business. Especially in the culinary business. This study aims to determine the Quality of Service, Product Quality and Price proposed for Consumer Satisfaction (Y). This type of method used is a qualitative method, questionnaire data 96 respondents from a total of unlimited participants. The results of the study showed that there was an influence between Service Quality, Price, and Customer Satisfaction, while Product Quality did not oppose Consumer Satisfaction in the Oto Bento Villa Nusa Indah Resto. t-count = - 0.788 Price variable obtained value t-count = 4.089 while t-table obtained using the value of absent (α = 5% obtained value = 1.664), t-count value of variables X1 and X3 is greater than the value of t-table, H1 is accepted and H0 Bento Villa Nusa Indah, while the calculated value of X2 is smaller than the table value, H1 is rejected and H0 is accepted which is related to the quality of the product to the Customer Satisfaction in Resto Oto Bento Villa Nusa Indah.

Abstrak

Persaingan bisnis saat ini yang semakin ketat, dari para produsen dituntut untuk selalu berfikir kreatif dan kritis dalam mengembangkan bisnis. Penelitian ini bertujuan untuk mengetahui Kualitas Pelayanan, Kualitas Produk  dan Harga berpengaruh terhadap Kepuasan Konsumen (Y). Jenis metode yang digunakan adalah metode kualitatif, data kuesioner 96 orang responden dari total populasi yang tidak terbatas. Hasil dari penelitian menunjukkan ada pengaruh secara parsial antara Kualitas Pelayanan, Harga, terhadap Kepuasan Konsumen sedangkan Kualitas Produk tidak berpengaruh terhadap Kepuasan Konsumen pada Resto Oto Bento Villa Nusa Indah Uji thitung (signifikan korelasi ) untuk variabel Kualitas Pelayanan diperoleh nilai thitung= 5,953, variabel Kualitas Produk diperoleh nilai thitung = - 0,788 variabel Harga diperoleh nilai thitung = 4,089 sementara ttabel yang diperoleh mengunakan nilai alpa (α=5% diperoleh nilai sebesar = 1,664), nilai thitung variabel X1 dan X3 lebih besar dari pada nilai ttabel, H1 diterima dan H0 ditolak yang artinya terdapat pengaruh antara Kualitas Pelayanan dan Harga terhadap Kepuasan Konsumen pada Resto Oto Bento villa nusa indah, sedangkan nilai thitung variabel X2 lebih kecil daripada nilai ttabel, H1 ditolak dan H0 diterima yang artinya tidak terdapat pengaruh antara Kualitas Produk terhadap Kepuasan Konsumen pada Resto Oto Bento villa nusa.
PENGARUH LINGKUNGAN KERJA TERHADAP MOTIVASI DAN DISIPLIN SERTA DAMPAKNYA PADA KINERJA
Authors: Wiryawan Tri , Risqon Risqon , Noncik Nyimas
Published: January 2020

Results of the conclusion of the study aimed to examine the positive influence of the Work Environment on Work Motivation, the positive influence of the Work Environment on Work Discipline, the positive influence of Work Motivation on Work Discipline, the positive influence of Work Discipline on Employee Performance, the positive influence of Work Motivation on Employee Performance.

Structural  Equation Modeling with the help of AMOS 21.0 is used to test the proposed hypotheses. After data analysis and in-depth discussion of the five hypotheses in this study, the following conclusions can be drawn. 1) The work environment has a positive effect on work motivation. 2) The work environment has no positive effect on work discipline. 3) Work motivation has a positive effect on work discipline. 4) Work motivation has a positive effect on employee performance. 5. Work discipline does not have a positive effect on employee performance

 

Abstrak

Hasil kesimpulan daripada penelitian yang  bertujuan untuk menguji pengaruh positif Lingkungan Kerja pada Motivasi Kerja, pengaruh positif  Lingkungan Kerja pada Disiplin Kerja, pengaruh positif Motivasi Kerja pada Disiplin Kerja, pengaruh positif Disiplin Kerja pada Kinerja Pegawai, pengaruh positif Motivasi Kerja pada Kinerja Pegawai. Structural Equation Modeling dengan bantuan AMOS 21.0 digunakan untuk menguji hipotesis-hipotesis yang diajukan. Setelah dilakukan analisis data dan pembahasan yang mendalam dari kelima hipotesis dalam penelitian ini dapat ditarik kesimpulan sebagai berikut.1) Lingkungan kerja berpengaruh positif pada motivasi kerja.2) Lingkungan kerja tidak berpengaruh positif pada disiplin kerja. 3) Motivasi kerja berpengaruh positif pada disiplin kerja. 4) Motivasi kerja berpengaruh positif pada kinerja pegawai. 5. Disiplin kerja tidak berpengaruh positif pada kinerja pegawai.
NILAI PERUSAHAAN: KEBIJAKAN HUTANG, KEBIJAKAN DIVIDEN DAN PROFITABILITAS
Authors: Taftazani Afif , Suryani Eka
Published: January 2020

This study aims to determine the effect of Debt to Equity Ratio (DER), Dividend Payout Ratio (DPR) and Return on Equity (ROE) on the value of the company or Price to book value (PBV) on the Indonesia Stock Exchange. The type of this research is quantitative research. The Data on this research is secondary data derived by collectin from literature and documentation. The sample in this study is 16 companies which listed on the Indonesia Stock Exchange in the 2012-2017 period. The sampling technique uses a non-probability sampling method. To analyze the data using a panel data regression test with software Eviews 9. The results of the analysis show that a partial debt to equity ratio has a positive and significant impact on firm value (PBV), while dividend payout ratio and return on equity have no significant impact on company value (PBV). The coefficient of determination (R2) is 0.9378 or 93.78%. This shows that 93.78% of the company's value (PBV) is influenced by the debt to equity ratio, dividend payout ratio and return on equity. While the remaining 6.22% of the company's value (PBV) is influenced by other factors.

Abstrak

Penelitian ini bertujuan untuk mengetahui pengaruh debt to equity ratio (DER), divident payout ratio (DPR) dan  return on equity (ROE)  terhadap nilai perusahaan (Price to book value) (PBV) di Bursa Efek Indonesia. Jenis penelitian yang digunakan dalam penelitian ini adalah penelitian kuantitatif. Data dalam penelitian ini menggunakan data sekunder yang berasal dari kepustakaan dan dokumentasi. Sampel dalam penelitian ini adalah 16 perusahaan yang terdaftar dalam Bursa Efek Indonesia periode 2012-2017. Teknik pengambilan sampel dalam penelitian ini menggunakan metode non probality sampling. Analisis yang digunakan menggunakan uji regresi panel dengan software eviews 9.  Berdasarkan analisis data yang dilakukkan dalam analisis menunjukkan debt to equity  ratio secara parsial berpengaruh secara positif dan signifikan terhadap nilai perusahaan (PBV), sedangkan dividend payout ratio dan return on equity tidak berpengaruh terhadap nilai perusahaan (PBV). Koefisien determinasi (R2) sebesar 0,9378 atau sebesar 93,78%.  Ini menunjukkakn bahwa 93,78%  nilai perusahaan (PBV) dipengaruhi oleh debt to equity ratio, dividend payout ratio dan.  return on equity.  Sedangkan sisanya sebesar 6,22% nilai perusahaan (PBV) dipengaruhi oleh faktor lain
High-performance asymmetric supercapacitor made of NiMoO4 nanorods@Co3O4 on a cellulose-based carbon aerogel
Authors: Wang Meixia , Zhang Jing , Yi Xibin , Liu Benxue , Zhao Xinfu , Liu Xiaochan
Published: January 2020

In this study, a new nanoporous material comprising NiMoO4 nanorods and Co3O4 nanoparticles derived from ZIF-67 supported by a cellulose-based carbon aerogel (CA) has been successfully synthesized using a two-step hydrothermal method. Due to its chemical composition, the large specific surface and the hierarchical porous structure, the NiMoO4@Co3O4/CA ternary composite yields electrodes with an enhanced specific capacitance of 436.9 C/g at a current density of 0.5 A/g and an excellent rate capability of 70.7% capacitance retention at 5.0 A/g. Moreover, an advanced asymmetric supercapacitor (ASC) is assembled using the NiMoO4@Co3O4/CA ternary composite as the positive electrode and activated carbon as the negative electrode. The ASC device exhibits a large capacitance of 125.4 F/g at 0.5 A/g, a maximum energy density of 34.1 Wh/kg at a power density of 208.8 W/kg as well as a good cyclic stability (84% after 2000 cycles), indicating its wide applicability in energy storage. Finally, our results provide a general approach to the construction of CA and MOF-based composite materials with hierarchical porous structure for potential applications in supercapacitors.
[1,3]/[1,4]-Sulfur atom migration in β-hydroxyalkylphosphine sulfides
Authors: Włodarczyk Katarzyna , Borowski Piotr , Stankevič Marek
Published: January 2020

β-Hydroxyalkylphosphine sulfides undergo [1,3]- or [1,4]-sulfur atom phosphorus-to-carbon migration in the presence of Lewis or Brønsted acids. The direction of sulfur atom migration depends on the type of acid used for the reaction. In the presence of a Brønsted acid, mainly [1,3]-rearrangement is observed, whereas a Lewis acid catalyzes the [1,4]-sulfur migration. To gain insight into the mechanism of these transformations, the stereochemistry of these rearrangements have been tested, along with the conduction of some control experiments and DFT calculations.