bluuebunny/crossref_metadata_2025 huggingface dataset:
PROPOSTA DE UM INSTRUMENTO DE COLETA DE DADOS EVIDENCIANDO A RELAÇÃO DA DIABETES MELLITUS TIPO 1 E DOENÇA TIREOIDIANA AUTOIMUNE
Authors: Costa Alaíde Policarpo , Xavier Marcio Osvan Rezende Rocha , Silva Isabella Lorrayne , Corgozinho Marta Lamounier Moura Vargas , Ferreira Lindiane Lopes , Silva Rafaela de Oliveira , Oliveira Sabrynna Brito
Published: January 2022

Introdução: O Diabetes Mellitus tipo 1 (DM1) é doença caracterizada pela insuficiência de insulina devido à perda das células β, levando à hiperglicemia. A incidência do DM1 tem sido frequentemente associada a doenças autoimunes, como as tireoidites. No entanto, tem-se observado uma maior propensão de pacientes com disfunções tireoidianas em desenvolver Doenças Tireoidianas Autoimunes (DAT) e a inexistência de consenso, na literatura, sobre os métodos de identificação da disfunção tireoidiana em pacientes com DM1. Objetivo: Objetivou-se criar instrumento de coleta de dados para avaliar a incidência, prevalência e identificar o perfil clínico de pacientes com DM1 que desenvolveram alterações na tireoide, de modo a observar a sua reprodutibilidade na obtenção de dados epidemiológicos. Metodologia: Trata-se de um estudo do tipo metodológico, estruturado em quatro etapas: criação de um instrumento de coleta de dados, validação do conteúdo, refinamento do instrumento e simulação de coleta de dados. Resultado: O primeiro instrumento de coleta de dados elaborado com base na literatura científica retornou aos pesquisadores com a recomendação de inserção das seguintes variáveis: Anti-TPO, Anti-GAD, tabagismo, etilismo, outras doenças autoimunes, gestações. Ao utilizar esse instrumento em uma simulação, percebeu-se que poderiam ser incluídos os tópicos: complicação, impacto da doença, limitações, condição socioeconômica, para se ter uma visão mais ampla do perfil do paciente e da prevalência das doenças autoimunes. Conclusão: O estudo demonstrou ser fundamental o aprimoramento das fichas de coleta de dados a fim de tornar mais preciso o rastreamento de DTA logo após o diagnóstico de DM1.
Growth performance of brown-golden marine microalga, Isochrysis sp., cultivated in alternative algal culture media
Authors: Tan Nai Han , Liew Kit Shing , Muhamad Shaleh Sitti Raehanah , Lim Leong Seng
Published: January 2022

The present study aimed to evaluate the suitability of introduced algal culture media as an alternative to the general enriched seawater media in the laboratory cultivation of Isochrysis sp., a marine microalga commonly cultivated for aquaculture purposes. Isochrysis sp. was established into culture in three replications using three experimental algal culture media (Walne’s medium as a control, China-contributed culture medium (CCM) and CCM supplemented with vitamins (CCM + Vit)). The experiment was performed with a continuous illumination for a period of seven days at 25±1°C. The effect of introduced algal culture media (CCM and CCM + Vit) on the growth performance of Isochrysis sp. was highlighted. CCM demonstrated promising results for the cultivation of Isochrysis sp. A maximum cell density of 9.16×106 ± 5.40×105 cells mL-1, which corresponded to an instantaneous growth rate (r) of 0.21 cell day-1 and a doubling time (T2) of 3.29 days, was observed in Isochrysis sp. cultivated in CCM. In view of its potential and reduced preparation labour, CCM may be recommended as an alternative to the general enriched seawater media in the cultivation of Isochrysis sp. in laboratories with basic facility as well as small- and medium-scale aquaculture hatcheries.
Understanding microplastics in aquatic ecosystems – A mini review
Authors: Soo Chen Lin , Sabana Shahirah , Chen Cheng Ann , Hii Yii Siang
Published: January 2022

Microplastic is defined as plastic debris with a size less than 5mm. It is characterized based on colour, shape, and polymer type. Microplastics have been discovered in a variety of aquatic environments, including freshwater, estuarine, and marine waters. The presence of microplastic in aquatic systems poses a threat not only to aquatic organisms, but to human consumers of food harvested from these environments. This paper reviews the key characteristics of microplastics, how they contaminate aquatic ecosystems, and their effects on aquatic organisms. Efforts have been made to highlight the knowledge gaps in these areas and measures that deserve attention for addressing the problem.
Immersive Technologies in 5G-Enabled Applications: Some Technical Challenges of the Novel Usage Models
Authors: Rendevski Nikola , Bocevska Andrijana , Kotevski Zoran , Dimovski Tome
Published: January 2022

5G next-generation networking paradigm with its envisioned capacity, coverage, and data transfer rates provide a developmental field for novel applications scenarios. Virtual, Mixed, and Augmented Reality will play a key role as visualization, interaction, and information delivery platforms. The recent hardware and software developments in immersive technologies including AR, VR and MR in terms of the commercial availability of advanced headsets equipped with XR-accelerated processing units and Software Development Kits (SDKs) are significantly increasing the penetration of such devices for entertainment, corporate and industrial use. This trend creates next-generation usage models which rise serious technical challenges within all networking and software architecture levels to support the immersive digital transformation. The focus of this paper is to detect, discuss and propose system development approaches and architectures for successful integration of the immersive technologies in the future information and communication concepts like Tactile Internet and Internet of Skills.
Creating 3D Models with 3D Printing Process
Authors: Popovski Filip , Mijakovska Svetlana , Popovska Hristina Dimova , Nalevska Gorica Popovska
Published: January 2022

This scientific paper will cover the process of creating two 3D objects, accompanied by a brief history of 3D printing technology, designing the model in CAD software, saving in appropriate format supported by the 3D printer, features of technology and the printer, materials from which the object can be made and examples where the products created by the 3D printing process can be applied. The printing of models was made by the studio "Xtrude Design & 3D Print" in Skopje. Two 3D models have been printed. A creative model of intertwined 4 triangles in STL file format has been made, which will be transferred and printed with PLA material. The model with the heart on the stand is printed with popular FDM process also with PLA material which is biodegradable and environmentally friendly. Both models are printed on Anet A8 3D printer. Different printing times, layer thicknesses and cost price of producion we have in our research.
Question Answering Module Leveraging Heterogeneous Datasets
Authors: Govindan Abinaya , Ranjan Gyan , Verma Amit
Published: January 2022

Question Answering has been a well-researched NLP area over recent years. It has become necessary for users to be able to query through the variety of information available - be it structured or unstructured. In this paper, we propose a Question Answering module which a) can consume a variety of data formats - a heterogeneous data pipeline, which ingests data from product manuals, technical data forums, internal discussion forums, groups, etc. b) addresses practical challenges faced in real-life situations by pointing to the exact segment of the manual or chat threads which can solve a user query c) provides segments of texts when deemed relevant, based on user query and business context. Our solution provides a comprehensive and detailed pipeline that is composed of elaborate data ingestion, data parsing, indexing, and querying modules. Our solution is capable of handling a plethora of data sources such as text, images, tables, community forums, and flow charts. Our studies performed on a variety of business-specific datasets represent the necessity of custom pipelines like the proposed one to solve several real-world document question-answering.
RESOURCES OF UNDERGROWTH FRUIT PLANTS IN PINE AND BIRCH FORESTS OF THE SOUTHERN TAIGA SUBZONE OF THE SVERDLOVSK REGION
Authors: Боярский А.А. , Аржанников Ю.А. , Панин И.А.
Published: January 2022

В статье представлены результаты изучения ресурсов дикорастущих плодовых растений подлеска сосновых и берёзовых насаждений южно-уральской таёжной зоны Свердловской области. В качестве основного показателя характеристики запасов было выбрано количество экземпляров на гектаре (густота). Кроме того, определялась текущая биологическая урожайность плодов в год наблюдения. Данные были получены на 28 пробных площадях в пяти наиболее распространённых в районе исследования типах леса. Для размещения пробных площадей подбирались наиболее типичные для района исследования насаждения различного возраста, происхождения, состава древостоя, относительной полноты и других таксационных показателей. Плодовые растения подлеска представлены 8 видами. Это рябина обыкновенная Sorbus aucupatia L., малина обыкновенная Rubus idaeus L., черёмуха обыкновенная Pronus padus L., облепиха крушиновидная Hippophae rhamnoides L., яблоня Malus P. Mill, боярышник кроваво-красный Crataegus sanguinea Pall. и ирга овальная Melanchier rotundifolia Dum. Cours. Лесопокрытые площади района исследования характеризуются низкими запасами плодов дикорастущих растений подлеска. Они непригодны для организации промышленного сбора. Совокупная урожайность плодовых растений подлеска всех видов на заложенных ПП не превышает 36,0 кг/га.

The article presents results of studying of resources of wild fruit plants of undergrowth of pine and birch plantations of the south ural taiga zone of the Sverdlovsk region. The number of specimens per hectare (density) was chosen as the main indicator of stock characteristics. In addition, the current biological yield of fruits in the year of observation was determined. Data were obtained on 28 test areas inve most common types of forest in area of study. To place sample areas, most typical plantings of various age, origin, composition of the stand, relative completeness and other taxation indicators were selected for study area. The fruit plants of understory are represented by 8 species: mountain ash Sorbus aucupatia L., raspberry Rubus idaeus L., bird cherry Pronus padus L., sea buckthorn buckthorn Hippophae rhamnoides L., apple Malus P. Mill, hawthorn Crataegus sanguinea Pall. and irga oval Melanchier rotundifolia Dum.Cours. The forested areas of the research area are characterized by low stocks of fruits of wild plants of the understory. They are not suitable for the organization of industrial collection. The total yield of fruit plants of undergrowth of all types on the laid PP does not exceed 36.0 kg/ha.
A influência do legado Freireano na organização do trabalho pedagógico em tempos de pandemia.
Authors: Nascimento Jéssica Villanova do , Miranda Anadir dos Reis , Bastos Eliana Nunes Maciel
Published: January 2022

Este artigo aborda a experiência de organização do trabalho pedagógico na Secretaria Municipal de Educação de Pinhais/PR em tempos de pandemia, a qual foi amplamente fundamentada nos princípios Freireanos de liberdade, autonomia, dialogicidade, amorosidade, em suma, na necessidade de humanização dos processos pedagógicos em prol da construção de uma educação e de uma sociedade mais justa, equânime e inclusiva. Entendeu-se, enquanto rede municipal de ensino, que as incertezas trazidas pelo contexto da pandemia exigiriam mais do que nunca uma gestão e prática pedagógicas imbricadas pela amorosidade, pela escuta, pela troca, pelo esforço em compreender e respeitar o lugar e a perspectiva do outro, enfim, pela construção coletiva pautada na ação de todos e todas. Somente a partir desta perspectiva seria possível garantir minimamente os direitos de aprendizagem de educandas e educandos da rede municipal, os quais repentinamente se encontraram “fora” da escola, carentes das interações sociais e educacionais, menos assistidos pelo poder público. Nesse sentido, mostrou-se fundamental resgatar princípios Freireanos e democráticos, entendendo-se que os diferentes sujeitos da comunidade escolar - profissionais da educação, familiares e responsáveis, educandos e educandas - precisariam enfrentar o grande desafio de estabelecer relações ainda mais amorosas, dialógicas e inclusivas à distância, fazendo uso, em grande parte, de ferramentas de interação remota.
Sobre os métodos de pesquisa na ciências da educação: passos teóricos iniciais e aproximações práticas preliminares
Authors: Nunes César
Published: January 2022

Estudo descritivo e análise qualitativa das teorias e das práticas de pesquisas em Educação. Abordagem histórica, contextualização filosófica e explicitação epistemológica das principais características das teorias e das metodologias da investigação científica voltadas para a pesquisa sobre a Educação e sobre sua prática social. Didática da pesquisa em Educação, apresentação das etapas e dos passos da investigação científica em Educação. Explicitação das diferentes metodologias da pesquisa em Educação, seus fundamentos epistemológicos e seus condicionamentos políticos. Delimitação dos enfoques teóricos matriciais das abordagens hegemônicas em pesquisa nas Ciências da Educação, suas características e suas singulares disposições institucionais.
As abordagens pós-modernas na pesquisa em educação e suas bases políticas derivadas do neoliberalismo: primeiras aproximações
Authors: Gamboa Silvio A. S. , Machado Carlos Eduardo
Published: January 2022

Abordagem filosófica, histórica e política, dos conceitos de Liberalismo, de Neoliberalismo e de Pós-Modernidade. Analisa os contextos históricos e as premissas ontológicas e epistemológicas da Modernidade e das projeções mais comuns na abordagem Pós-Moderna. Estudo descritivo e aproximativo, sob o enfoque histórico-crítico, de concepções de mundo e de conhecimento. Debate as causalidades da eclosão do projeto Neoliberal e suas articulações políticas e sociais. Aponta as contradições do enfoque pós-moderno de abordagem teórico-metodológica e questiona sua possibilidade de superação das causalidades reais. Interpreta as repercussões do Neoliberalismo e da metodologia Pós-Moderna na Pesquisa em Educação.
Política educacional e metodologia da pesquisa para a autonomia na perspectiva da prática formativa à distância: como fazer?
Authors: Romão Eliana Sampaio , Salaro Camila Pedroso
Published: January 2022

A categoria Autonomia lembra a condição humana de governar-se e se autodeterminar, de modo a alcançar seus fins sob sua própria lei, isento de qualquer “fator estranho” ou “influência externa”. Isso não é novo. Entrar no mundo e extrair de si mesmo “o bem” de modo a conduzir seu próprio destino, por muito tempo, foi a palavra de ordem. Essa discussão ganha destaque no campo da educação, em particular, na educação a distância (EaD). Programas de EAD se afirmam há décadas tendo como suporte principal o princípio da autonomia, pois conduzir com autonomia os estudos é um fator importante para lidar com a distância e a presença. Nessa pesquisa e no presente artigo dela decorrente utilizamos o método de índole qualitativa que se fez caminhar por meio de narrativas e teve como objetivo compreender o que  subjaz ao agir com autonomia, com a centralidade de sua relação com a  dialogia. Os resultados mostram que muitos alunos têm dificuldades de agir com autonomiia e de exercê-la de par com o diálogo. Autonomia, para além de estudo autodirigido,  pouco aproxima-se de autodidatismo. Conclui-se que esse caminho é social e pedagogicamente construído e evolui para além de autodeterminar a ação. Seu entendimento implica em certo grau de abrangência e de profundidade e sua internalização é construída antes do ingresso em formas não tradicionais de ensino.
A Comparison between Evaporation Ponds and Evaporation Surfaces as a Source of the Concentrated Salt Brine for Salt Gradient Maintenance at Tajoura’s Solar Pond
Authors: Ramadan Abdulghani , Agha Khairy , Abughres Saleh
Published: January 2022

One of the main problems that negatively affect the operation of salt gradient solar ponds and influence its thermal stability is the maintenance of salt gradient profile Evaporation pond (EP) is designed to generate the salt which is lost by upward salt diffusionfrom the lower convective zone (LCZ) of the solar pond. Another attractive method is the Evaporation Surface facility (ES). Regions with moderate to high precipitation favor Evaporation Surfaces over Evaporation Ponds. Dry climates will generally favor Evaporation Ponds for the brine re-concentration. In previous studies [1-3], the authors have shown that the (EP) of Tajoura’s Experimental Solar Pond (TESP) is undersized and can provide only about 30% of the salt required by a Salt Gradient Solar pond (SGSP). The anticipated size of (EP) was estimated and presented in those studies under different design conditions, including Summer, Autumn and Spring designs, while the winter design was excluded due to the low rates of net evaporation during the winter season.In addition, the results presented were predicted for the first three years of operation. The daily variations of brine concentration in the (EP) of (TESP) and those based on different designs were predicted and discussed under different scenarios. The quantities of brine provided by the evaporation pond and that required by SGSP were predicted for both cases of surface water flushing (fresh water and sea-water) under the different design conditions as shown in Table 1. This paper investigates the differences between (EP) and (ES) as a source for salt brine generation by evaporation. The effect of (EP) depth on the area ratio and daily variations of salt concentrations for three years of operation is shown. Results show that evaporation can be a reasonable method for salt brine generation. Reducing the depth of (EP) improves the capability of (EP) for brine re-concentration. It also increases the (EP) surface area for the same quantity of saline water used. Therefore, ESs are more powerful than Eps in salt re-concentration.
Simone et André Schwarz-Bart, Hommage à la femme noire (réédition, 2 tomes), Le Lamentin (Martinique), Caraïbéditions, 2020-2021.
Authors: Margras Fanny
Published: January 2022

La réédition de l’Hommage à la femme noire en mars 2020 et mai 2021 marque un tournant pour cette œuvre, communément décrite comme une « encyclopédie ». Sortant de l’ombre un ouvrage onéreux et difficilement accessible, l’éditeur caribéen CaraïbEditions offre au regard le travail de Simone et André Schwarz-Bart, trente ans après sa première parution. Il inscrit cette réédition dans une volonté pédagogique d’ouverture au plus grand nombre de lecteurs possible, et de diffusion maximale : ce faisant, il s’affranchit de ce qui apparaît comme des poids dans la production et la distribution d’ouvrages littéraires. Ce compte rendu tente de réunir les questions posées par la réédition de l’ouvrage, de l’absence d’illustrations au subtil changement opéré dans la signature, de « Simone Schwarz-Bart » à « Simone et André Schwarz-Bart ».
Explaining the Absence of a Regional Hegemon in the Central African Sub-region
Authors: Nkumbe Enongene Rex , Njie Makolo Joseph
Published: January 2022

The end of the Cold War saw a shift in power dynamics globally, changing the security dynamics of many regions globally including those in Africa. With the security void left by these great powers in Africa, regional hegemons have played significant roles in promoting regional peace and stability. Regional hegemons have greatly helped to sustain peace and stability in the Economic Community of West African States (ECOWAS) and Southern African Development Community (SADC), but this has not been the case in the Economic Community of Central African States (ECCAS). This paper seeks reasons why no hegemon (dominant state) exists in the ECCAS region. The study analyses the material resource capacities of regional members and argues that a multiplicity of regional groupings, internal political instability, economic challenges and the neo-colonial hand of France accounts for the absence of a hegemon in the region.
ESTREITANDO CAMINHOS PARA A APRENDIZAGEM: CARL ROGERS E A TEORIA DA APRENDIZAGEM CENTRADA NO ALUNO
Authors: Sousa Isete da Silva
Published: January 2022

Muitos são os teóricos que contribuíram para o estreitamento entre de relações entre psicologia e aprendizagem, no entanto, nessa pesquisa optou-se pela abordagem Humanista de Carl Rogers, através da Teoria da Aprendizagem centrada no aluno. O objetivo do estudo foi analisar as relações entre psicologia e educação, assim como evidenciar a importante contribuição desse estudioso para uma maior eficácia no processo de aprendizagem e desenvolvimento social e afetivo da criança. A metodologia aplicada nessa pesquisa foi a bibliográfica, através da qual foram feitas a apresentação e análise de conceitos e o pensamento de Rogers, de modo a trazer suas contribuições no campo da Educação para o contexto atual.
LA SEGURIDAD INFORMÁTICA EN LAS INSTITUCIONES DE
EDUCACIÓN SUPERIOR
Authors: Mat J.M. Salazar , Navarro C. Cruz , Sánchez A. V. Balderas , Uribe H. F. Díaz
Published: January 2022

El incremento exagerado del uso de la internet, de los diferentes dispositivos y de sistemas digitales, tanto para le educación, como para uso de las redes sociales y compras en línea por parte de los usuarios, es generado a consecuencia de la larga contingencia causada por el SARS-COV2 (Covid19). Esto a su vez, ha ocasionado un incremento en los fraudes cibernéticos; alrededor de 500 mil ataques reportados con un costo de 6,000 millones en todo el mundo, y en México está dentro de los primeros 10 países más atacados con un 61%. Estos robos, afectan tanto a personas comunes como a empresas de todo tipo y tamaño (chicas, medianas y grandes), así como empresas privadas y de gobierno. Esto hechos han generado un déficit en el personal profesional capacitado de 1.8 millones en el mundo y en México de 35 mil, en las áreas de la ciberseguridad, como es hacking ético y cómputo forense y otras más. Con ello se tiene una gran oportunidad, para proponer asignaturas, cursos, capacitaciones en área de ciberseguridad, así como una especialidad de “Administración de redes y ciberseguridad”, para la carrera de Ingeniería en Sistemas Computacionales, que genere competencias acordes a esta problemática. Logrando con ello abatir el gran déficit de personal capacitado en estas áreas, logrando así que la información sea más segura en las empresas, considerando que el crimen cibernético es cada vez más recurrente, se puede combatir con la prevención, la ética y el profesionalismo.
Late Quaternary landform evolution and sedimentary successions in the Miaoli Tableland, northwestern Taiwan
Authors: Liu Shih-Hung , Hebenstreit Robert , Böse Margot
Published: January 2022

Abstract. Elevated Quaternary sedimentary complexes in the western
foreland of the central mountain ranges of Taiwan are called tablelands.
Their mostly flat surfaces are deeply incised by fluvial processes. The
landforms and the fluvial systems in the Miaoli Tableland are investigated
by high-resolution terrain analyses based on different datasets. Sediments
are described in 51 outcrops and characterized by grain size composition.
The outcrops revealed complete or incomplete sequences of the general scheme from bottom to top: sandy tidal–coastal units overlain by
gravel- and cobble-rich fluvial deposits always with a fine-grained silt-rich
top cover layer influenced by aeolian deposits. All layers are
unconsolidated sediments. Three subtypes of this sequence were identified,
with respect to the occurrence of the fluvial deposits. The relation of
tectonic and erosional processes including the rework of gravels is
discussed. The results reveal a tableland surface much more disaggregated than
previously mapped, suggesting that individual tableland segments represent
remnants of an inferred palaeotopography. The tableland surfaces have been
separated into Sedimentary Highlands (SH-I and SH-II) and Sedimentary Terraces
(ST) by geometrical properties. The Alluvial and Coastal Plains (AL)
represent broad valley bottoms (“box-shaped valleys”) in the dendritic
drainage systems below 150 m and the coastal plains. The landforms and
predominantly the sediment sequences are discussed in the context of the
existing stratigraphical schemes of the Toukoshan Formation and the so far
rarely used Lungkang Formation. The latter is recommended as the
stratigraphical term for the refined subdivision of the uppermost part of
late Quaternary sediments in the Miaoli Tableland.
Experimental analysis of the dynamic inflow effect due to coherent gusts
Authors: Berger Frederik , Neuhaus Lars , Onnen David , Hölling Michael , Schepers Gerard , Kühn Martin
Published: January 2022

Abstract. The dynamic inflow effect describes the unsteady aerodynamic response to fast changes in rotor loading, due to the inertia of the wake. For pitch actuation and fast rotor speed changes this effect leads to load overshoots. The effect is suspected to be also relevant for gust situations, however this was never shown. The objective of the paper is to proove the dynamic inflow effect due to gusts and compare dynamic inflow engineering models to corresponding measurements. A 1.8 m diameter model turbine is used in the large wind tunnel of ForWind – University of Oldenburg with an active grid to impress rotor uniform gusts on the flow. The campaign features load and velocity measurements of the axial flow in the rotor plane. The unsteady dynamic inflow effect is investigated by comparing two experimental cases. Firstly, a dynamic measurement during a gust situation is performed. Secondly, quasi-steady loads and axial velocities are interpolated from a steady characterisation experiment according to the gust wind speed. By comparing both cases, the influence attributed to the dynamic inflow effect is isolated. Further comparisons to a typical Blade Element Momentum code and a higher fidelity Free VortexWake Model are performed. Based on analytical considerations an improvemed formulation of the Øye dynamic inflow model is proposed. The experiment shows a dynamic inflow effect due to gusts in the loads and axial velocity measurements. It leads to a reduction in load and axial velocity amplitudes and consequently also lower fatigue loading. The higher fidelity model shows a similar impact of the dynamic inflow effect. In contrast, the commonly used Øye engineering model in the BEM code predicts an increase in load amplitude and thus higher fatigue loads. The improved Øye engineering model however catches the observed dynamic inflow effect due to gusts in accordance to the experiment and FVWM simulations. An amplification of induced velocities, seen in the experiment and FVWM simulation, causes the reduced load amplitudes. Therefore, classic dynamic inflow models, which filter the induced velocity, cannot predict the effect. The proposed improvement to additionally consider the wake velocity for the filter of the dynamic inflow engineering model, proves to be a straight forward but also effective modification. In conclusion, these new experimental findings on dynamic inflow due to gusts and improvements to the Øye model enable improvements in wind turbine design by catching the related lower fatigue loads.
Social Responses to Climate Change and Extreme Weather in the Age of Charlemagne (740-820)
Authors: Devroey Jean-Pierre
Published: January 2022

Over the past two decades, the growing availability of paleoclimatic data has opened new opportunities for cross-fertilisation and comparison between natural and social sciences. The parallel history of climate and the environment is often undertaken in a holistic manner, assuming simple and direct causalities between the climate and social change. Faced with climatic series, the historian must question the nature of the data and their specific conditions of gathering, validity, and environment, as well as the methods and objectives of modelling. Comparing paleoclimatic data and primary sources requires considering their specific limitations and finding a common scale of observation. A historical case study has just been conducted using climate series and sources from the age of Charlemagne (740-820 AD), a time interval of 80 years that is compatible with the heuristic requirements of both disciplines. The investigation confronts paleoclimatic data and interpretations with Frankish sources from 740 to 820, starting from the analysis of the famines of 779, 791-794 and recurrent subsistence phenomena at the beginning of the 9th century, studying in parallel cosmologies and representations, and the political, economic, and social responses brought by the political system.
Viaggio nell'utopia. Da Alfonsine a Mosca senza mai arrivare
Authors: Bianchi Davide
Published: January 2022

Over the Summer of 1957, seven people from Alfonsine travel to Moscow, for the World Festival of Youth and Students – the Soviet cultural weapon. Enzo Pasi, one of the seven, carries his 8 mm camera with him, with which he provides records of a unique moment in the Twentieth Century. The journey not only occurs within a complex political climate, but it is also the source for an in-detail overview concerning the relationship between tourism and amateur cinema.
"ԱՊԱՍՏԱՆ ՀԱՅՑՈՂՆԵՐ", "ՆԵՐՔԻՆ ՏԵՂԱՀԱՆՎԱԾ ԱՆՁԻՆՔ", "ՀԱՐԿԱԴԻՐ ՎԵՐԱԲՆԱԿՎԱԾ/ՏԵՂԱՀԱՆՎԱԾ ԱՆՁԻՆՔ" ԵԶՐՈՒՅԹՆԵՐԸ, ԿԱՐԳԱՎԻՃԱԿՆԵՐԸ. ԴՐԱՆՑ ԻՄՊԼԵՄԵՆՏԱՑԻԱՅԻ ԱՆՀՐԱԺԵՇՏՈՒԹՅՈՒՆՆ ԱՐՑԱԽԻ ԻՐԱՎԱԿԱՆ ԴԱՇՏՈՒՄ
Authors: MKHITARYAN ELINA
Published: January 2022

The objective of the article is to raise the terms ''asylum seekers'', ''internally dispaced persons'', ''forced resettlement/displaced persons'', consider the legal statuses corresponding to these terms, study international law and legal documents and compare them with national legislation.
Study of the problems posed within the article, were used individual (personal) or special methods - legal-comparative, analytical, statistical, systemic, as well as general scientific, such as dialectical, logical, historical methods. Our task is clarify the features of these legal statuses, to present notional /domestic/ legal problems associated with the above statuses.
The result of the research is the conclusion that it is necessary to immediatly reflect in the legislation the post-war realities that are associated with the determination of the legal status of displaced persons due to the 44-day aggression of Azerbaijan.
The purpose of the article is to highlight the terms "asylum seekers", "internally displaced persons", "internally resettled/displaced persons", to study international legal documents that fix the legal provisions corresponding to them, as well as to compare them with the legislation in force in Artsakh and comment on the real and legal situation of those who have not received these status de jure but de facto are the carriers. The issue of legal consolidation of more than 36,000 persons deported from their place of permanent residence as a result of the Azerbaijani aggression on September 27, 2020, including refugees deported from Azerbaijan in 1988-1992, as well as the issue of legal consolidation of the current situation of internally displaced persons due to the first Artsakh war of 1991-1994, is rightly relevant.
Our task is to explain the features of the above-mentioned legal status, to present domestic legal problems related to the above-mentioned statuses, in some cases-problems that have arisen due to their absence in the legal field, to invite the competent circles, the competent authorities to submit for discussion an extension of the above-mentioned concepts, possibly a new status, respectively, the need for their succession for the realization of the rights of persons bearing them.
In the course of studying the tasks set in the framework of the article, general scientific, dialectical, logical, historical, as well as private or special methods were used, which are: legal, analytical, statistical, structural methods.
As a result of the study, we came to the conclusion that it is necessary to immediately reflect the post-war realities associated with determining the status of displaced persons and consolidating its socio-economic guarantees in the legislative field.
ԱՆՁԻ ՏՆՏԵՍԱԿԱՆ ՎԱՐՔԻ ՄՈԴԵԼԱՎՈՐՄԱՆ ԳՈՐԾԸՆԹԱՑԻ ՀՈԳԵԲԱՆԱԿԱՆ ՕՐԻՆԱՉԱՓՈՒԹՅՈՒՆՆԵՐԻ ԲԱՑԱՀԱՅՏՄԱՆ ՄԵԹՈԴԱԲԱՆԱԿԱՆ ՀԻՄՔԵՐԸ
Authors: VOSKANYAN KARLEN
Published: January 2022

The purpose of this article is to present the interdisciplinary approaches that exist in the modeling process based on the psychological regularities of a person’s economic behavior. This article discusses the economic behavior of a person and issues of its effectiveness from both economic and psychological points of view. Based on the economic perception of the concept of efficiency, the hypothesis of its relativity from a psychological point of view is put forward. Relativity is conditioned by the fact that a person displays occasional behavior guided by incidental motives arising from situations which cannot be considered effective from an economic point of view. In this context, the task was to substantiate the point of view according to which the economic behavior of a person should be considered a dynamic system governed by a combination of economic, psychological and socio-political factors, the modeling process of which should be based not only on deductive, but also on inductive approaches...
ԱՎԵՏԱՐԱՆԻՉՆԵՐԻ ԴԻՄԱՆԿԱՐՆԵՐԸ ԹՈՐՈՍ ՏԱՐՈՆԱՑՈՒ ԱՐՎԵՍՏՈՒՄ
Authors: NAZARYAN NAIRA
Published: January 2022

The article is dedicated to the portrait of the Evangelists by Toros Taronatsi, a miniaturist of Gladzor University of the first half of the XIV c․ The study of the portraits of Evangelists is an important part of our research. Toros Taronatsi was one of the most famous painters of medieval Armenia, but his legacy has not yet been thoroughly explored to this day. Our choice fell on studying the art of Taronatsi for this very reason. The purpose of studying the work of Toros Taronatsi is to shu the features of his illustrated manuscripts, the artist's skills in the field of miniature painting. The main objective of the article is the analysis of the main components that make up the portrait of the Evangelists illustration system: Evangelist image, vestment, codex, lectern, instruments, tabouret, architectural background. The study used complex method of artistic analysis. Studying the portraits of evangelists of Taronatsi, we came to the conclusion, that there is an Armenian pre-Cilician, Cilician and Byzantine elements in the work of the master, the portraits correspond to the standard types generally accepted in Christian art.
Editorial
Authors: Nigel Krauth Jen Webb,
Published: January 2022

This year’s AAWP conference, Alchemy, is subtitled Blending Researchand Creativity. It is not alone in this focus; this year, humanities scholars and social scientists have been meeting across Australia in seminars, fora and conferences, and communicating through special-issue publications, to discuss one or both of these topics. They are building on a growing conversation among researchers…
Creative Writers on Campus: Dead Spies, Living Lies, 1593 to the Present
Authors: Harper Graeme
Published: January 2022

It strikes me that we talk, as creative writers on campus, too much in the contemporary. It strikes me that we talk too often as if education in the writing arts is something we recently invented. As if, not only have we invented it but that we children of the twentieth century, perhaps in this generation or the one before ours, have taken on a divine duty to defend it…
The Romantic Ego in the Creative Writing Workshop
Authors: Edmonds Phillip
Published: January 2022

As in the broader picture, where many are hoping for fifteen minutes of fame, it could be fatal for all concerned to take emotional responsibility for the anxieties of the ‘romantic’ ego manifested in some students. But, in writing this paper, I hope I have shown that by being clear about what we are doing we can in turn be truly responsible for all our students, and hopefully, we can interrogate the brutal fearfulness of the contemporary romantic ego.
Cyber-Psychopathy Trait as Predictor of Cybersex Addiction among University Students
Authors: Bilal Ahmad , Nadeem Arif , Saleem Muhammad
Published: January 2022

The previous studies have established a link between dark triad personality traits and cybersex addiction. However, there is a scarcity of studies on the link between psychopathy and cybersex addiction. Therefore, the present study was conducted to find an association and to predict cybersex addiction from psychopathy. 160 undergraduate students from the Baghdad campus of Islamia University of Bahawalpur were recruited randomly to participate in the study. All the participating students signed the informed consent form before taking part in the study. The locally standardized versions of The Internet Addiction Test – Sex (IAT-Sex) and Cyber-Psychopathy Scale (CPS) were used to collect the data. The data was analyzed through the Statistical Package for Social Sciences (SPSS, v 25) and expressed in the form of correlation, regression analysis, and t-test. The study found a significant positive correlation between psychopathy and cybersex addiction. Psychopathy significantly predicted cybersex addiction. Moreover, the male students showed more psychopathy and cybersex addiction than female students. The students of 21-22 years were found to show more psychopathy and cybersex addiction as compared to students of other age groups. The study proposed that future studies be conducted with a broader sample from other universities and by including other demographic variables to make the results generalizable to a larger population.
Development and Characterization of Repaglinide Loaded Floating Microparticles
Authors: Singh Ajeet , Singh Ranjit
Published: January 2022

Sustained release drug delivery has been successfully achieved using microparticles made from natural or synthetic polymers. The aim of this study is to develop and test floating microparticles of Repaglinide in order to improve drug bioavailability by extending gastric residence time. Repaglinide, an oral hypoglycemic, is a lipophilic drug that is rapidly absorbed from the stomach and eliminated with a half-life of just 1 h, so suitable to be formulated as floating drug delivery system for sustained release.Repaglinide floating microparticles were developed using an ionotropic gelation method that included calcium chloride as a cross-linking agent, sodium alginate, and different concentrations of hydroxypropyl methylcellulose (HPMC), ethyl cellulose (EC), and sodium bicarbonate (NaHCO3). A three factor, three-level Box-Behnken design was used to study the effect of independent variables on dependent variables. In the formulation of microparticles, the amount of hydroxypropyl methylcellulose (X1), ethyl cellulose (X2), and sodium bicarbonate (X3) were three independent variables, while percentage buoyancy (Y1) and percentage drug release at 10 h (Y2) were dependent variables. Micromeritic properties, percent yield, percent drug entrapment performance, surface morphology, percent buoyancy, in-vitro drug release, and drug excipient compatibility were all assessed in the formulations.FTIR studies revealed no interaction between the drug and the excipients.SEM for surface morphology studies revealed that their surface is spherical and smooth. The mean particle size of formulations was found to be between 415- 689 µm, the drug entrapment efficiency was found to be between 44.65% - 76.55% and percent buoyancy was noted to be between 63%- 78.33%. The results revealed that entrapment efficiency increased as polymer concentration was increased. The cumulative percent drug release after 10 h was noted to be between 76.87- 88.12%. Percent drug release decreased as polymers concentration was increased. The buoyancy was increased with increasing concentration of sodium bicarbonate. The developed microparticles could successfully retard the release of the drug.
Efficacy of Merremia mammosa Hall Terpenoid Fraction againts Mycobacterium tuberculosis
Authors: Agil Mangestuti , Studiawan Herra , Purwitasari Neny
Published: January 2022

Tuberculosis is still a pandemic disease in Indonesia. People in Madura Island, Indonesia, usually use the rhizome of Merremia mammosa Hall as anti-tuberculosis. In this study, the antibacterial activity of terpenoid fractions of Merremia mammosa rhizome against Mycobacterium tuberculosis has been studied using agar dilution method at a concentration of 200-25 µg/mL, incubated for 21 days in 7H10 Midlebrook medium. N-hexane extract of Merremia mammosa has been fractionated using ethyl acetate. The ethyl acetate fraction was subjected to vacuum column chromatography using gradient concentration of ethyl acetate-n hexane, and obtained 11 subfractions. There were two subfractions indicated the presence of terpenoid compounds. These subfractions were grouped and subjected to antimicrobial assay. Result showed that the terpenoid compounds have antituberculosis property with minimum inhibition concentration (MIC) value of 100µg/mL. The result was supported by acid -fast Zielh-neelsen stain, which indicated that at a concentration of 100 and 200 µg/ml of the subfractions, there were no growth of Mycobacterium tuberculosis visually detected. In conclusion, Merremia mammosa is potential to be developed as antituberculosis agent. The chemical compounds responsible for this activity are currently under investigation for further study.
In silico Investigation of Natural compounds identified from Ocimum species as Dengue NS3 and NS5 Protein Inhibitors
Authors: Suganya Jeyabaskar , Kumar G. Rajesh , Radha Mahendran , S Dhananya
Published: January 2022

Nature has bestowed on us a very rich botanical wealth. Plants are the richest resource of drugs molecules for modern medicines, nutraceuticals, traditional medicine and even chemical entities for synthetic drugs. Ocimum species (Tulasi) is a well-known medicinal plant which has used in the six Indian systems of medicine from ancient times. The latest review on the Ocimum species revealed that the species holds a very good antiviral activity. For last few years the prevalence of dengue has increased dramatically in both urban and rural area of India. The current management of Dengue is mainly symptomatic and supportive treatment with fluid management. The main purpose of this study was to analyze the inhibitory action of phytochemical compounds were identified from the plant species Ocimum through literature survey by computational docking studies. Thus docking result revealed that only one compound Bornyl acetate exhibited the best binding interaction with in the active site of the dengue viral protein through hydrogen bonding interaction. Further in vitro studies on Bornyl acetate compounds from the Ocimum species can lead to the discovery of novel viral inhibitor.
Bioremediation of Kitchen wastes through Mushroom Cultivation and Study their Phytochemical and Antioxidant Potential using GCMS Chromatogram
Authors: S. Jeyabharathi , N Jeenathunisa , N Sathammaipriya , V Aruna
Published: January 2022

Mushrooms are liked for his or her delicious flavor, low calorific value and high protein contents, vitamins of B group and minerals. During this present study focused the cultivation of Calocybe indica Mushroom using Composted Organic wastes arising from Cauvery College Hostel Kitchen. The cultivated Mushroom studied for Phytochemical analysis and that they show Alkaloides, Steroids, Terpenoides, Flavonoides, Phenols, Tanins, Aminoacids and Proteins.The Reducing sugar and Carbohydrates were absent. During Antibacterial activity of Ethanolic extract of Calocybe shows higher Antibacterial activity. While performing Chromotographic studies like Gas chromatography and mass spectroscopy standards under different concentration of extracts shows all non-essential aminoalkanoic acid profile and Benzene, Etheyl-, Benzene,1,2,3-Trimethyl,1-Octadecene,1,4-Benzenedicarboxylicacid,bis(2-ethylexyl) ester, Cyclohexane, Eicosyl,Carbonic, Methyl nonyl ester,Phenol,2-(1-phenyethyl) promising antimicrobial agents and n-Hexadecanoic acid, 9,12-Octadecadienoic acid(Z,Z) , Phenol,2-(1-Phenylethyl) and Piperazine-2,5-dione,1,4-dimethyl-3,3’-bis- compounds showed anti oxidant potentials. All the results showed the Calocybe indica may be a promising nutritive Mushroom hence it should recommended for protein malnourished Children and adults as part of their regular diet.
The Effect of Andrographis paniculata Nees on Oxidative Stress and Parasitemia Levels of Plasmodium berghei Infected Rats
Authors: Shinta Amat Anita Lidesna , Ilmi Hilkatul , Tumewu Lidya , Notopuro Harianto , Setyawati Tantular Indah , Fuad Hafid Achmad , Widyawaruyanti Aty
Published: January 2022

Background: During malaria infection, oxidative stress arises due to the high metabolic rate of the multiplying parasite within the erythrocyte. Malondialdehyde (MDA), a product of lipid peroxidation and glutathione (GSH) has been suggested as a biomarker of oxidative stress. The Ethyl acetate (EA) fraction from the ethanol extract of Andrographis paniculata was shown to inhibit Plasmodium berghei in vivo. However, the antimalarial mechanism of the EA fraction, specifically on oxidative stress has not been investigated previously. Therefore, this study aimed to investigate the effects of the EA fraction on parasitemia levels, GSH and MDA levels of P. berghei infected rats. Methods: Female Wistar rats infected with P. berghei were divided into three groups. Group one received no treatment (negative control), group two was treated with 1.4 mg/200 g body weight of chloroquine diphosphate as positive control, and group three was treated with the EA fraction at a dose equal to andrographolide 3.5 mg/200 g body weight. The treatments lasted for four days (day 0 to day 3) and parasitemia was observed from day 0 to day 4. Rats were sacrificed and blood taken intracardially on day 4 after parasitemia observation. GSH was measured using an ELISA reader at a wavelength of 415 nm. MDA was observed via spectrophotometry at a wavelength of 532 nm. Results: The EA fraction at a dose equal to andrographolide 3.5 mg/200 g body weight was able to inhibit parasite growth by 81.97±9.14%. The GSH levels of the negative control, positive control and EA fraction treated group were 139.30±75.93 μMol/mL, 81.06±53.26 μMol/mL and 105.71±76.00 μMol/mL, respectively. Furthermore, the MDA level of negative control, positive control and EA fraction treated group were 11.18±0.70 nMol mL, 8.81±1.26 nMol/mL and 9.40±0.74 nMol/mL, respectively. No significant differences were detected between treatment groups regarding their GSH levels. Additionally, there was a significant difference in MDA levels between the negative control and positive control groups; as well as a significant difference between the negative control and the EA treated group. However, no significant difference in MDA levels between the EA fraction treated group and positive control group. Interestingly, a correlation was found between parasite growth inhibition and MDA levels among groups (p<0.05). Conclusion: The EA fraction of A. paniculata significantly decreased MDA levels which correlated significantly with parasitemia levels of P. berghei infected rats. The antimalarial activity of the EA fraction may have been correlated with oxidative stress mechanisms and this correlation could be explained in part by the decreased production of MDA.