bluuebunny/crossref_metadata_2025 huggingface dataset:
STRUCTURING A SPECIAL PART CRIMINAL LAW (ON THE EXAMPLE OF THE FRANCE CRIMINAL CODE)
Authors: Голенко Диана Викторовна
Published: February 2022

Проанализировано построение Особенной части действующего Уголовного кодекса Франции. Рассмотрены структурные компоненты в их взаимосвязи. Осуществлено сравнение структурных единиц французского уголовного кодекса и действующего российского уголовного закона. Французский уголовный кодекс включает компоненты, непривычные для российского юриста (например, книги, отделы, подотделы, параграфы). Их число значительно превышает число структурных единиц в российском уголовном законе. Автор разбирает особенности и строение каждой структурной единицы. Обращено внимание, что Особенная часть во французском уголовном кодексе не выделена в качестве самостоятельного структурного компонента, но по содержанию к ней могут быть отнесены книги, начиная со II. Каждая из книг имеет свою структуру, внутреннюю нумерацию. При этом ни одна из книг, которые можно отнести к Особенной части, не содержит всего перечня структурных компонентов. Несмотря на кажущееся сходство в последовательности расположения статей о преступлениях (открывают Особенную часть французского уголовного закона также преступления против личности), содержание их отличается.

The structure of the Special Part of the current French Criminal Code has been analyzed. Structural components in their interconnection have been considered. The structural units of the French Criminal Code and the current Russian Criminal Law are compared. The French Criminal Code includes components that are unusual for a Russian lawyer (for example, books, departments, subsections, paragraphs Their number significantly exceeds the number of structural units in the Russian criminal law. The author examines the features and structure of each structural unit. It is drawn attention that the Special part in the French Criminal Code is not singled out as an independent structural component, but according to the content, books can be attributed to it. , starting with II. Each of the books has its own structure, internal numbering. Moreover, none of the books that can be attributed to the Special Part contains the entire list of structural components. crimes (they open a special part of the French criminal law also crimes against the person), their content is different.
SUBJECT AND LIMITS OF PROOF IN CRIMINAL CASE
Authors: Макеева Инна Владимировна
Published: February 2022

Как известно, основным условием исследования преступлений органами предварительного расследования и судом выступает правильное определение предмета доказывания в рамках каждого отдельно взятого уголовного дела. В целом, можно заключить, что предмет доказывания является одним из исходных положений доказательственного права. Верное определение предмета доказывания и пределов доказывания обеспечивает полноту и всесторонность исследования обстоятельств дела. Поэтому так важно уметь выделить границы, в которых осуществляется собирание и оценка доказательств: это способствует упорядочению процесса сбора и оценки доказательств в достаточном объеме. В статье рассматриваются структура и содержание предмета доказывания, а также исследуются различные подходы к пониманию предмета и пределов доказывания.

It is known, the main condition for crimes investigation by the bodies of preliminary investigation and the court is the correct proof subject determination in each individual criminal case. In general, we can conclude that the subject of proof is one of the initial provisions of the law of evidence. Correct definition of the subject of proof and the limits of proof ensures a complete and comprehensive study of all the circumstances of the case. Therefore, it is so important to be able to identify the boundaries in which collection and assessment of evidence is carried out: this helps to streamline the process of collecting and evaluating evidence in a sufficient volume. The article examines the structure and content of the subject of proof, and also explores various approaches to understanding the subject and limits of proof.
INSTITUTE OF MEDIATION IN RUSSIA: MAIN PROBLEMS AND DEVELOPMENT PROSPECTS
Authors: Любовенко Елена Сергеевна
Published: February 2022

Раскрывается вопрос значимости для нашего государства процедуры медиации. Дается оценка существующим достижениям в сфере правового регулирования медиации и намеченным главой государства направлениям развития этого института. В целях объективности за основу был взят международный опыт, а также опыт Грузии как страны на постсовестком пространстве.

Reveals the question of the importance of the mediation procedure for our state. An assessment of the existing achievements in the field of legal regulation of mediation and the directions of development of this institution outlined by the head of state is given. For the sake of objectivity, international experience was taken as a basis, as well as the experience of Georgia as a country in the post-Soviet space.
Perancangan Website E-Commerce Penjualan Ikan Cupang
Authors: Kristianingrum Vira , Al-Fadillah Muhammad Fizkry Yusuf
Published: February 2022

E-Commerce adalah transaksi penjualan dan pembelian yang melalui sistem elektronik yang tersambung oleh internet. Dalam beberapa tahun terakhir, penjualan online berkembang pesat sejalan seiringnya perkembangan teknologi saat ini yang membuat kita memerlukan metode atau sistem dalam meningkatkan produktivitas dan efisiensi untuk menyampaikan informasi tentang penjualan produk di situs web, mengingat kecepatan dalam pemrosesan informasi menjadi satu hal yang sangat penting, terutama di dunia bisnis dan perdagangan. Dari banyaknya jenis ikan hias, yang menarik perhatian dan cukup mudah untuk dipelihara dan mempunyai banyak peminat atau kolektor nya adalah Ikan cupang. Tapi tidak banyak yang menjual nya secara online. Oleh karena itu, ikan cupang bisa kita jadikan bisnis online supaya mempermudah pembeli yang hanya menunggu dirumah.
The expression of essential selenoproteins during development requires SECIS-binding protein 2–like
Authors: Kiledjian Nora T , Shah Rushvi , Vetick Michael B , Copeland Paul R
Published: February 2022

The dietary requirement for selenium is based on its incorporation into selenoproteins, which contain the amino acid selenocysteine (Sec). The Sec insertion sequence (SECIS) is an RNA structure found in the 3′ UTR of all selenoprotein mRNAs, and it is required to convert in-frame UGA codons from termination to Sec-incorporating codons. SECIS-binding protein 2 (Sbp2) is required for Sec incorporation, but its paralogue, SECIS-binding protein 2–like (Secisbp2l), while conserved, has no known function. Here we determined the relative roles of Sbp2 and Secisbp2l by introducing CRISPR mutations in both genes in zebrafish. By monitoring selenoprotein synthesis with 75Se labeling during embryogenesis, we found that sbp2−/− embryos still make a select subset of selenoproteins but secisbp2l−/− embryos retain the full complement. Abrogation of both genes completely prevents selenoprotein synthesis and juveniles die at 14 days post fertilization. Embryos lacking Sbp2 are sensitive to oxidative stress and express the stress marker Vtg1. We propose a model where Secisbp2l is required to promote essential selenoprotein synthesis when Sbp2 activity is compromised.
CHALLENGES AND POTENTIAL SOLUTIONS OF MODERN HEALTH CARE SYSTEM USING INTERNET OF THINGS
Authors:   P.E.S. College of Engineering, Aurangabad, Maharashtra. India., Ansari Tashfin , G.K Awasthi ,   Vivekanand College, Aurangabad, Maharashtra. India., Bhale Satyam ,   Vivekanand College Aurangabad, Maharashtra. India
Published: February 2022

Health is one of the sustainable development areas in all of the countries. The Internet of Things (IoT) is a process of interlinked computing devices, mechanical and digital machines, objects, animals or people that are provided with unique identifiers. Internet of Things (IoT) rises as a powerful domain where embedded devices and sensors can connect and exchange information over the Internet. Among all the application IOT (Internet of Things) has grease the wheels around the world and has gained a lot of popularity due to its efficiency and great performance, researchers are working very hard in order to convert nearly about each and every device with IOT. In this research paper we have explained the role of IOT technology in healthcare system. This technology has become the ultimate building blocks in the development of healthcare monitoring system. So in this paper we also highlighted the implementation of IOT in healthcare monitoring systems and the standard model for application in future internet of things healthcare system.
FUTURE OF INTERNET OF EVERYTHING (IOE)
Authors:   Botho University, Gaborone, Botswana, Kumar Rajiv , Narayanan Sreekumar ,   Botho University, Gaborone, Botswana, Kaur Gurjeet ,   GSSS, Nilokheri, India
Published: February 2022

In the world, the man matters, not the machine, people need to be care, not data. There is transition from information technology to human technology. The answer is internet of everything (IoE). The internet of everything (IoE) is a concept that extends the internet of things (IOT) by encompassing the machine-to-machine (M2M) communication, machine-to-people (M2P) and technology-assisted people-to-people (P2P) with expended digital features. It includes different types of devices, appliances and items that are connected to the global internet. The internet of everything (IoE) comprises four components, namely, people, process, data and things to make the networked connections more relevant and valuable. These components enable us to create new capabilities, wide experiences and economic opportunity for individuals and businesses. IoE connects people in more relevant and valuable ways, deliver the right information to the right people and/or machine at the right time, leverages data into more useful information for decision making and connect physical devices and objects with each other via the internet of things (IoT). The IoE includes user-generated communications and interactions associated with the global internet. The IoE is 5G technology that include evolution, elasticity, capacity, speed and agility. In this research work, we discuss the potentiality of IoE technology that includes the seamless interconnections and autonomous coordination among people, data and process through the global internet infrastructure. We will highlight the various applications of IoE in the area of privacy and security. Security and privacy are the major challenge in today world. There are various challenges like software and hardware compatibility, wired and wireless infrastructure, data analysis, data mining, big data and many other things that need to be solves globally. We will discuss the security aspects of IoE that ensure the securing the environment, the infrastructure and the process. Data collection is also the major challenge at the network edge. It includes multitude of endpoint devices and sensors that automatically collect, analyze and transmit the data on the massive scale and at very fast rate. Internet of everything (IoE) will have a huge impact on individuals and business in the next few years. It will be a radial shift to think that how we live, solve the problem, create value, secure environment to keep people, data, process and things under one umbrella. It will include devices and objects at the massive scale. The network capabilities will create the new experiences, capabilities and economic opportunities for individuals, businesses and governments. In short, the internet of everything (IoE) changes only one thing, which is everything.
RAINFALL PREDICTION USING REGRESSION AND MULTIPLE ALGORITHMS
Authors:   Vidyalankar Institute of Technology Wadala, Mumbai, India, Jalgaonkar Mrunmay
Published: February 2022

Rainfall is very important aspect for farmers in day-to-day agriculture and also very important in prospect to Indian economical growth. As now a day we see there is daily climate change in our India as there no stable season any month the rainfall occurs in India which also cause damage to the farming industry as the crop seeds gets damaged. In the proposed study the future rainfall is predicted using Linear Regression Technique as we also compared various model such as SVM, Random Forest Regression, Neural Network model so we obtained better results in Linear Regression so we further consider this model for future prediction of rainfall.
Long-term Performance of Going Public through SPACs
Authors: Park Youngkyu
Published: February 2022

Despite a surge in the merger of companies listed on the KOSDAQ market with special purpose acquisition companies (SPACs), limited domestic studies have systematically compared the listing through SPAC mergers and the general IPO. This study analyzes the impact of such companies going public after merging with SPACs as well as their performance by comparing them with the conventional IPOs. First, the firms listed through SPAC mergers are smaller and have a higher proportion of non-manufacturing industries than the conventional IPOs. Second, the operational and stock price performance of the firms listed through SPACs are not inferior to that of the conventional IPOs. Finally, a higher share allocation to institutional investors and subscription rates, for the shares recorded at the time of the SPAC listing, are related to the stock price performance observed after SPAC mergers. According to the empirical results of this study, going public by merging with SPACs provides early listing opportunities to small- and medium-sized companies; they do not experience a deterioration in their financial performance after being listed. The listing of SPACs creates a different and valuable path to enter the KOSDAQ market for such companies as compared to the conventional IPOs.
Determination of the residual amounts of cefotaxime in liquid media using piezoelectric sensors
Authors: Zyablov A. N. , Shapovalova A. A.
Published: February 2022

The goal of the study is to develop a piezoelectric sensor based on a molecularly imprinted polymer (MIP) for the determination of cefotaxime in liquid media. To obtain an antibiotic-selective sensor, the electrode surface of was modified with a molecularly imprinted polymer. A pre-polymerization mixture was prepared using a copolymer of 1,2,4,5-benzoltetracarboxylic acid and 4,4’-diaminodiphenyloxide, and an aqueous solution of cefotaxime in a ratio of 1:1. Then a two-stage thermoimidization was carried out in a drying cabinet at a temperatures of 80 and 120°C. After that, the sensor was cooled to room temperature and placed in distilled water for 24 h. An imprinting factor (IF = 40.9) and a selectivity coefficient were calculated to assess the ability of a sensor with MIP (cefotaxime) to recognize a template molecule. A low selectivity of a MIP sensor with the cefotaxime imprint to other cephalosporin antibiotics is revealed. The experiments were carried out on an original installation including a piezoelectric sensor, a portable generator, and an MP732 USB-frequency meter connected to a computer. Piezoelectric quartz resonators of AT-cut with silver electrodes with a diameter of 5 mm and a thickness of 0.3 mm with a nominal resonant frequency of 4.00 MHz were used as sensors. The determination of antibiotics in model solutions was carried out by the method of calibration schedule. The range of detectable concentrations (0.1 – 1.0 × 10–4 g/dm3) was experimentally determined. The detection limit of cefotaxime is 1.0 × 10–5 g/dm3. The correctness of the cefotaxime determination of in individual and binary model solutions was verified by the «spike-test». It has been shown that a sensor with MIP-cefotaxime is not sensitive to an extraneous antibiotic. The relative standard deviation does not exceed 10 %.
THE STRUCTURE OF THE STAFFING THE MUSEUM AS AN OBJECT OF INFORMATIZATION
Authors:   Russian State University for the Humanities, Grishina Natalia V.
Published: February 2022

As a result of the use of information technologies in their work, museums have acquired qualitatively new opportunities for the registration of exhibits, the preservation of electronic copies of the documents and exhibits, as well as the mode of access to exhibits. Museums strive to become interesting, fashionable, interactive, educational. The modern museum can be fully called an object of informatization. In order to realize all modern possibilities, museums must be staffed with modern personnel. A modern museum worker is not just an art critic with relevant knowledge. A modern museum worker must confidently master the information technologies and use them in the practice. The article analyzes the dynamics of changes in the staff of museum workers over the past six years. It presents the diagram of the distribution of museum workers by the age groups and shows the distribution of museum workers according to their experience. There is an analysis in ratio of the number of men and women among museum workers. The paper analyzes some aspects of staffing the museum as an object of informatization.
SCIENTOMETRIC INDICES OF THE PUBLICATION ACTIVITY OF RUSSIAN SCIENTISTS IN THE FIELD OF ECOLOGY (2016-2020)
Authors:   Russian National Public Library for Science and Technology, Borgoyakova Kristina S. ,   Moscow State Linguistic University
Published: February 2022

The article presents the results of scientometric analysis of the Russian document flow in the field of ecology over the past 5 years (2016-2020) based on scientific citation databases (Web of Science Core Collection (WoS CC), Scopus, Google Scholar and RSCI), special attention is paid to WoS CC and Scopus. The leading positions in the number of publications were identified (the first 3 positions are considered): authors, affiliated organizations, funding organizations, branches of science, types of documents, publications. The data on the scientometric indices of the publication activity of Russian scientists in the field of ecology are considered in more detail especially according to such indices as the number of publications, the number of citations, the Hirsch index and the percentile for the RSCI core. The article presents dynamics of the publication activity of Russian researchers in the field of ecology on the considered databases of scientific citation, as well as it gives a comparison of indices and the years in which the largest number of publications are recorded. The study revealed a possible correlation of the international and national events with a surge in the publication activity of Russian researchers. It is noted that the scientometric analysis of the industry document flow allows the solution of following tasks: to identify the most productive authors, to identify organizations whose employees are actively publishing in the area, to highlight the organizations participating in the funding of scientific research in the area under consideration, to determine the branches of science in which scientific research is developing in the area.
Perception and treatment of melancholy in the writings of Hildegard of Bingen (c. 1098-1179)
Authors: Sakalauskaitë-Juodeikienë Eglė
Published: February 2022

Hildegard of Bingen (c. 1098-1179) was a medieval nun and an abbess, a mystic, a composer, a poet, an author of medical treatises, and one of the few women at the time who wrote both theological and scientific texts. In this paper, I analyze Hildegard’s book Liber subtilitatum diversarum naturarum creaturarum (Book of Subtleties of the Diverse Nature of Creatures), compiled around 1151-1158 and consisting of two books: Physica and Causae et curae. The aim of this study is to understand how the phenomenon of melancholy in its three meanings (as body fluid, character type, and a disease) was perceived by one of the brightest medieval thinkers. Even though Hildegard’s writings were influenced by deep knowledge of the Scripture, the abbess also accepted Greco-Roman medical system (classical humoral theory), astrology, medieval agricultural worldview, and the wisdom of folk medicine. Melancholy was interpreted in Hildegard’s medical texts as a heart and a brain disease which was caused by the overabundance of black bile produced in the spleen. The abbess recommended various medicinal herbs (fennel, mallow, primrose, rue, etc.) and substances of animal (ostrich, heron, ants) and mineral (onyx) origin in order to reduce excessive amount of black bile. Hildegard explained the mechanism of action of these medications using concepts of humoral theory, principle of contraria contrariis, as well as knowledge of medieval folk medicine and elements of religious and magical healing.
Conversion from clinically isolated syndrome to multiple sclerosis: what paraclinical tests findings are the most characteristic?
Authors: Malciūtė M. , Čelpačenko I. , Stankevičiūtė R. , Balnytė R.
Published: February 2022

Background. Multiple sclerosis (MS) is a chronic demyelinating disease with clinical onset usually manifesting as clinically isolated syndrome (CIS). Approximately 70% of people with CIS convert to MS. Therefore, there is a pressing need to identify the most characteristic paraclinical test findings to predict CIS conversion to MS.Aim. The aim of this study was to establish the most characteristic paraclinical test findings for the identification of CIS conversion to MS.Materials and methods. A retrospective data analysis was performed in patients diagnosed with demyelinating encephalomyelitis according to ICD-10 (International Classification of Diseases Tenth Revision), codes G37.8 (other specified demyelinating diseases of central nervous system) and G37.9 (demyelinating disease of central nervous system, unspecified). In clinical practice, these diagnoses are called CIS. The data were obtained from medical records and included findings of paraclinical tests (magnetic resonance imaging (MRI), IgG levels and oligoclonal bands (OCBs) in cerebrospinal fluid (CSF), and brainstem auditory evoked potential (BAEP)) and final diagnosis. The patients were divided into 2 groups according to the final diagnosis (MS group and non-MS group) and into 3 age groups (18-30, 30-50, >50 years old). The prevalence and statistical difference of paraclinical tests were estimated between the groups. Chi-squared test was used to compare between categorical variables. Mann-Whitney U test was used to compare between the groups. The association between two quantitative variables was determined using Spearman correlation co-efficient. Results were interpreted as statistically significant when p-value <0.05.Results. A total of 138 cases were included in the study. 49 patients converted to MS (35.5%), other 89 patients (64.5%) were diagnosed with other diseases than MS. Unspecified MRI lesions (χ2=4.328, p=0.037, n=40), elevated IgG levels (χ2=10.793, p=0.001, n=36), and positive OCBs in CSF (χ2=34.859, p<0.001, n=30) were more prevalent in MS group compared to non-MS group. Moreover, lesions detected by the BAEP test were also more frequent among MS group (χ2=10.924, p<0.001, n=17).Conclusions. The results indicate that pathological CSF findings (positive OCBs, elevated IgG levels) and prolonged BAEP latency are characteristic in patients with CIS who later progress to MS. Unspecified brain MRI lesions are also distinctive for MS patients; however, this result should be interpreted with consideration due to methodological reasons
Early subjective cognitive disorders and their relationship with chronic diseases, subjective hearing difficulties, burnout syndrome, and depression among middle-aged women
Authors: Pečeliūnienė J. , Žukauskaitė I. , Dovydėnas V.
Published: February 2022

Introduction. With the increase in cognitive impairment among young people, it is important to timely identify and modify risk factors.The aim of the study was to evaluate early cognitive disorders in relationship with subjective hearing disorders, burnout syndrome, and depression among middle-aged women.Methods. The study involved 310 women aged 26 to 59 years (M=38.6). An online survey was created. Respondents filled in the Cognitive Failures Questionnaire (CFQ), Subjective Cognitive Complaints (SCCs) questionnaire, Shirom-Melamed Burnout Measure (SMBM), and Geriatric Depression Scale (GDS). Sociodemographic factors, addictions, subjectively reported presence of chronic diseases, and subjective hearing disorders were registered by the study questionnaire. Student’s t-test, Chi-square test, Fisher’s exact test, and logistic regression analysis (LRA) were used for data analysis.Results. 34 females (11%) had subjective cognitive failures (CF+ group) and 276 (89%) had not (CF- group). 28.7% of respondents had subjective cognitive complaints (SCC+ group) and 71.3% had not (SCC- group). 23 females (7.4%) had depression and 62 females (20%) were likely to be depressed. 34 (11%) females had significant symptoms of burnout. 30.6% (N=95) self-reported having chronic diseases. 14.84% of females had subjective hearing disorders. The CF+ group had higher GDS scores than the CF- group (M=6.88 vs. M=3.78, p<0.001). Hypothyroidism was the only disease in which differences between the SCC+ and the SCC- groups were found (12.4% vs. 4.5%, p=0.022). Respondents in the CF+ group more often had subjective hearing disorders compared to the CF- group (35.3% vs. 12.3%, p=0.001). The CF+ and the CF-, also the SCC+ and the SCC- groups did not differ by comparing alcohol and drug consumption habits.Conclusions. Depression, burnout syndrome, and subjective hearing disorders are related to subjective experienced cognitive dysfunction, and cognitive complaints are related to hypothyroidism in middle-aged women.
Anti-amphiphysin antibody-induced paraneoplastic-autoimmune encephalitis: case report and literature review
Authors: Kavaliauskaitė E. , Mameniškienė R.
Published: February 2022

Anti-amphiphysin antibody-induced encephalitis is an immune-mediated inflammatory disease of the brain caused by onconeuronal antibodies. Amphiphysin antibodies are associated with various paraneoplastic neurological syndromes and tumours. The absence of a particular clinical pattern and pathognomonic features makes diagnosing paraneoplastic-autoimmune encephalitis complicated, especially when a malignancy is not initially apparent. Detection of specific antibodies in serum and cerebrospinal fluid remains the main diagnostic tool. Up to this date, no cases with epileptic seizures as one of the clinical manifestations of anti-amphiphysin encephalitis have been reported. In this article, we present a rare clinical case of a 54-year-old man diagnosed with autoimmune-paraneoplastic encephalitis caused by antibodies against amphiphysin which manifested with atypical clinical symptoms such as epileptic seizures, visual and perception impairment, paraesthesia, and elevated CSF protein levels with no detectable tumour.
Staff perceptions of patient safety in the NHS ambulance services: an exploratory qualitative study
Authors: Shepard Keegan , Spencer Sally , Kelly Carol , Wankhade Paresh
Published: February 2022

Objectives: Most research investigating staff perceptions of patient safety has been based in primary care or hospitals, with little research on emergency services. Therefore, this study aimed to explore staff perceptions of patient safety in the NHS ambulance services.Design:
A stratified qualitative study using semi-structured interviews.Setting: Three urban or rural ambulance service NHS trusts in England.Participants: A total of 44 participants from three organisational levels, including executives, managers and operational staff.Methods:
The semi-structured interviews explored the interpretation and definition of patient safety, perceived risks, incident reporting, communication and organisational culture. The framework method of qualitative data analysis was used to analyse the interviews and NVivo software was used to manage
and organise the data.Results: We identified five dominant themes: varied interpretation of patient safety; significant patient safety risks; reporting culture shift; communication; and organisational culture. The findings demonstrated that staff perceptions of patient safety ranged
widely across the three organisational levels, while they remained consistent within those levels across the participating ambulance service NHS trusts in England.Conclusions: The findings suggest that participants from all organisational levels perceive that the NHS ambulance services
have become much safer for patients over recent years, which signifies an awareness of the historical issues and how they have been addressed. The inclusion of three distinct ambulance service NHS trusts and organisational levels provides deepened insight into the perceptions of patient safety
by staff. As the responses of participants were consistent across the three NHS trusts, the identified issues may be generic and have application in other ambulance and emergency service settings, with implications for health policy on a national basis.
Individual risk factors predictive of major trauma in pre-hospital injured older patients: a systematic review
Authors: Pandor Abdullah , Fuller Gordon , Essat Munira , Sabir Lisa , Holt Chris , Buckley Woods Helen , Chatha Hridesh
Published: February 2022

Background:Older adults with major trauma are frequently under-triaged, increasing the risk of preventable morbidity and mortality. The aim of this systematic review was to identify which individual risk factors and predictors are likely to increase the risk of major trauma in elderly patients presenting to emergency medical services (EMS) following injury, to inform future elderly triage tool development.Methods:Several electronic databases (including Medline, EMBASE, CINAHL and the Cochrane Library) were searched from inception to February 2021. Prospective or retrospective diagnostic studies were eligible if they examined a prognostic factor (often termed predictor or risk factor) for, or diagnostic test to identify, major trauma. Selection of studies, data extraction and risk of bias assessments using the Quality in Prognostic Studies (QUIPS) tool were undertaken independently by at least two reviewers. Narrative synthesis was used to summarise the findings.Results:Nine studies, all performed in US trauma networks, met review inclusion criteria. Vital signs (Glasgow Coma Scale (GCS) score, systolic blood pressure, respiratory rate and shock index with specific elderly cut-off points), EMS provider judgement, comorbidities and certain crash scene variables (other occupants injured, occupant not independently mobile and head-on collision) were identified as significant pre-hospital variables associated with major trauma in the elderly in multi-variable analyses. Heart rate and anticoagulant were not significant predictors. Included studies were at moderate or high risk of bias, with applicability concerns secondary to selected study populations.Conclusions:Existing pre-hospital major trauma triage tools could be optimised for elderly patients by including elderly-specific physiology thresholds. Future work should focus on more relevant reference standards and further evaluation of novel elderly relevant triage tool variables and thresholds.
Protocol for a scoping review on the development of policy, guidelines and protocols within emergency medical services
Authors: Renshaw John , Halter Mary , Quinn Tom
Published: February 2022

Introduction:Emergency medical services (EMS) use a combination of policy, clinical practice guidelines and protocols to set out their expectations for service delivery and to inform patient care. While these are integral to how EMS now operate, relatively little is known about how they are developed, or the processes involved. Therefore, the aim of this scoping review is to understand what is known in the literature about the development of policy, guidelines and protocols within EMS.Methods:This scoping review will follow the Arksey and O’Malley (2005) methodological framework for scoping reviews. A search strategy has been developed using index term definitions, building from authors’ knowledge of the field. The following electronic databases will be searched from 2002 to 2021 for all types of publication: CINAHL, Medline, Academic Search Complete and PsycINFO, EMBASE, Nursing and Allied Health, the Cochrane library, NICE Evidence, Scopus, OpenGrey, EThOS, Google Scholar, Google search and key EMS journal websites. The results will be downloaded using EndNoteX9reference management software and duplicates will be removed. Titles and abstracts of the results will be independently screened for their relevance to the research question, and the full text of each selected publication will be assessed against pre-determined inclusion and exclusion criteria to determine its eligibility. The reference list and forward citations will be searched for articles meeting the eligibility criteria. A second researcher will independently assess a 10% sample of results to allow for validation of this assessment. Data will be extracted and charted on the characteristics of the publications and the knowledge they contribute on the development of policy, guidelines or protocols. Accompanying narratives will be presented to identify themes and gaps in the available evidence. A critical appraisal will be undertaken of the included publications, where empirical research is presented.
EKONOMİK ÖZGÜRLÜK ENDEKSİ BORSA İLİŞKİSİNİN DEĞERLENDİRİLMESİ: MIST ÜLKELERİ ÜZERİNE BİR ARAŞTIRMA
Authors: ŞİT Ahmet
Published: February 2022

Bu çalışmanın amacı ekonomik özgürlük endeksinin borsa üzerindeki etkisini araştırmaktır. Bu amaçla MIST Ülke grubunda yer alan Ülkelerin 1996-2021 dönemi verileri kullanılmıştır. Çalışmada bağımlı değişken olarak, ülkelerde en fazla işlem gören şirketlerin yer aldığı borsa endeksleri, bağımsız değişken olarak da Heritage Vakfı tarafından ülkelere belirlenen ekonomik özgürlük endeksi kullanılmıştır. Çalışmada yöntem olarak sabit etki/ rassal etki yöntemi kullanılmıştır. Analiz sonucunda, ekonomik özgürlük endeksinin borsa üzerinde %1 anlamlılık düzeyinde çok etkili olduğu görülmektedir. Ülkelerin borsalarının gelişiminde ekonomik özgürlük endeksi skorlarının önemli olduğu sonucuna varılmıştır.
RİSK İŞTAH ENDEKSİ İLE BİST100 ENDEKSİ ARASINDAKİ İLİŞKİ: COVİD-19 ÖNCESİ VE SONRASI DÖNEME YÖNELİK BİR ARAŞTIRMA
Authors: KÖYCÜ Erol
Published: February 2022

Bu çalışmada, COVID-19 öncesi ve sonrası döneme yönelik yatırımcı risk iştahını ifade eden RISE endeksi ile BİST100 endeksi arasında nedensellik ilişkisinin varlığının araştırılması hedeflenmiştir. Bu amaç doğrultusunda, 15/03/2019 ile 13/03/2020 dönem arası COVID-19 öncesi dönem olarak sınıflandırılırken, 13/03/2020 ile 12/03/2021 dönem arası ise COVID-19 sonrası dönem olarak sınıflandırılmış ve her iki dönem için haftalık bazda veriler kullanılarak bir veri seti oluşturulmuştur. Mevcut çalışmada kullanılan tüm değişkenlerin doğal logaritmik getirileri alındıktan sonra seriler mevsimsel etkiden arındırılmış ve EViews10 programı yardımıyla ekonometrik analizler gerçekleştirilmiştir. Elde edilen bulgular neticesinde hem COVID-19 öncesi dönemde hem de COVID-19 sonrası dönemde BIST100 endeksinden RISE endeksine doğru %1 anlamlılık düzeyinde tek yönlü bir nedensellik ilişkisi tespit edilmiştir.
A COMPARATIVE STUDY OF M|M|1 and M|M|C MODELS FOR B2C WITH SUPPLY CHAIN PROCESS
Authors: Sharma Geetanjali , Pandey Jai Deep
Published: February 2022

With the emerging technology of electronic commerce, most of the business companies positively tend to offer services to their clients dealing in B2C e-commerce. We pro- posed four models for business to consumer (B2C) with supply chain management. First two models are M |M |1 with and without server breakdown and other models are M |M |C with and without server breakdown.  During service when the server breakdown, the re- pairing process of the server begins immediately. During repair period the server serves the customer   with slow rate   and   service period follows exponential   distribution.  Then numerical results are also illustrated various system performances are calculated
HBsAg and Immune Competency; is HBsAg a Mere Biomarker or a Therapeutic Target for Chronic Hepatitis B?
Authors: Kim Jin Hyang , Park Grace , Paratala Bhavna , Rijnbrand Rene , Sofia Michael J. , Hann Hie-Won
Published: February 2022

Hepatitis B virus (HBV) is a main cause of hepatocellular carcinoma (HCC) development. Although controversial, it is increasingly recognized that the immune responses directed against infected hepatocytes drive hepatic inflammation and tissue injury. Here we extended our previous findings to report that serum surface antigen (HBsAg) levels are a biomarker not only for HBV-specific immunity, but also for ongoing non-specific immune activation. We found that the HBV-specific T cell responses in patients with HBsAg < 500 IU/mL, while significantly higher than those in patients with HBsAg > 50,000 IU/mL, had already reached levels comparable to patients with seroclearance. In addition, lower HBsAg levels were associated with reduced non-specific immune activation, while no further reduction was observed with HBsAg < 500 IU/mL. We propose HBsAg is a therapeutic target for reducing inflammation.
Alergia alimentaria y su asociación con dermatitis atópica autorreportada en adultos jóvenes en Lima-Perú
Authors: Rojas-Puell María José , Runzer-Colmenares Fernando M. , Salazar-Gastelú Danna , Santa Cruz-De Lama Flor , Medina-Hernández Alejandra
Published: February 2022

Objetivo: Precisar la asociación entre dermatitis atópica y alergia alimentaria en estudiantes de Medicina Humana de una universidad privada de Lima, Perú.
Métodos: Estudio observacional, analítico, transversal, en el cual se incluyeron 355 estudiantes de medicina humana con edad entre 18 y 25 años, de una universidad privada de Lima, Perú, a través de una encuesta virtual. Los datos fueron analizados con la técnica de Fisher, t de Student y análisis de regresión de Poisson.
Resultados: En un modelo ajustado por edad y sexo, tener dermatitis atópica se asoció con 5.53 veces la probabilidad de tener alergia alimentaria (intervalo de confianza de 95 %, 3.12-9.79).
Conclusión: Existió asociación entre el antecedente de dermatitis atópica y haber reportado alergia alimentaria en 28.95 % de los estudiantes de medicina humana de una universidad privada de Lima, Perú.
Perfil clínico de los pacientes con urticaria crónica en un hospital de tercer nivel de atención del sistema de seguridad social de Costa Rica
Authors: Sedó-Mejía Giovanni , Lotz-Esquivel Stephanie , Monge-Ortega Olga Patricia , Pino-García Caridad
Published: February 2022

Objective: To describe the medical and laboratory profile of the patients who have been diagnosed with chronic urticaria in the outpatient clinic of a tertiary care hospital of the social security system in Costa Rica.
Methods: All patients over 13 years of age who had been diagnosed with chronic urticaria between January 1st, 2014, and December 31st, 2018 were included. Variables of medical and laboratory data were statistically analyzed, and the treatment of the patients between their first and last medical consultation was compared.
Results: This was about 160 patients who had been diagnosed with chronic urticaria; 129 of them were women, 45.7 % between the ages of 30-49 years; in 17.5 % of them (28 patients), inducible urticaria was associated; 54.8 % (46/84) had positive antithyroperoxidase antibodies; 16.9 % (27 patients) maintained a single dose of second-generation anti-H1 antihistamines in the last consultation; 16.3 % (26 patients) no longer required antihistamine treatment in the last consultation. Cyclosporine was used in 8.8 % (14 patients), and omalizumab was used in 2.5 % (four patients).
Conclusion: Since this is a real-life study in a geographic region with limited publications on this pathology, we trust that the provided information will contribute to the scientific community in order to improve the quality of life of patients with chronic urticaria through a timely diagnosis and an effective and efficient treatment.
Factores asociados al tabaquismo en pacientes con asma durante el confinamiento por COVID-19 en una región urbana con cifras elevadas de infecciones por SARS-CoV-2
Authors: Vázquez Eliza Mireya , Vázquez-Rodiguez Carlos Francisco , Ortega-Betancourt Nancy Virginia , Martínez-Montoya Humberto , Castillo-Ruiz Octelina , Vázquez-Nava Francisco
Published: February 2022

Objetivo: Determinar la prevalencia y factores de riesgo asociados al tabaquismo durante el periodo de confinamiento ante la pandemia de COVID-19.
Métodos: Mediante un estudio analítico y transversal se analizaron los datos de 2372 participantes. La recolección de la información se realizó con un cuestionario autoadministrado construido con la herramienta Google Forms, el cual se distribuyó y aplicó a través de correo electrónico y de la plataforma de mensajería privada WhatsApp. La relación entre las variables independientes y la resultante fue determinada a través de regresión logística multivariada.
Resultados: De la población total, 69.3 % fue del sexo femenino, la edad media de 20.11 ± 2.01 años, la prevalencia de asma de 12.2 % y la de tabaquismo activo, de 13.3 %. Una mayor proporción de pacientes con asma fumaba (14.2 versus 13,2 %), en comparación con quienes no padecían asma. La regresión logística multivariante mostró que considerar que COVID-19 no existe y no cumplir con el confinamiento se relacionaron con el tabaquismo en pacientes con asma durante la aplicación del plan de contingencia que representa la pandemia de COVID-19.
Conclusiones: Durante el confinamiento en casa por COVID-19, la prevalencia de tabaquismo es mayor en pacientes con asma comparados con los individuos sin esta enfermedad, los factores que favorecen lo anterior están presentes en el entorno familiar.
A Study on the Textbook Composition and Teacher Perception on ‘The Function Represented by a Parameter’
Authors:   The Korea Society Of Educational Studies In Mathematics, Yang Seong Hyun
Published: February 2022

Clarity and consistency of terms are more important in mathematics than in any other discipline. Mathematics terminology can be an essential clue to understanding a mathematical concept. Moreover, it can evoke images related to the concept both during the learning process and after learning. However, the evoked image may fail to match the original mathematical concept accurately if a student has a misconception about a specific mathematical term. This paper specified the ambiguity and inconsistency of the expression “the function represented by a parameter” used in textbooks. Further, it investigated the teachers’ perceptions caused by the phrase. Teacher responses in a survey showed that teachers perceived the words in various ways, and some teachers demonstrated mathematical misconceptions. Additionally, the teachers recognized the need to revise the phrase, “the function represented by a parameter.” Our study implicates that unclear and inconsistent uses of mathematical terms in textbooks and teacher’s guide books might contribute to teacher misunderstandings, which can directly or indirectly affect students.
Teacher Noticing for Supporting Student Proving: Gradual Articulation
Authors:   The Korea Society Of Educational Studies In Mathematics, Kim Hangil
Published: February 2022

Proof has been paid much attention in school mathematics and the literature. To date, the extant literature has focused more on difficulties in teaching and learning of proof rather than support that can help teachers to teach proof and develop student’s understanding about proof. This study examined a teacher’s practice that offers an explicit instruction of proof as part of everyday lesson. The results showed that the teacher supports student proving by way of teacher noticing with a clear definition of proof in the literature and that teacher noticing instructional practice needs to be more attuned for teaching proof. In particular, the teacher’s moves for supporting student proving differ by what aspects of proof that the teacher pays attention to at a given time and by judgement on whether an argument qualifies as a valid proof. This instructional practice would provide a guidance and foundation for teachers to engage students in proving as part of everyday lesson.
IMPLEMENTASI NILAI-NILAI PANCASILA DALAM MEMBANGUN SIKAP DISIPLIN PADA SISWA SMAN 1 SEKONGKANG
Authors: Cahya Dwi , Fauzan Ahmad , Zubair Muh
Published: February 2022

ABSTRAKPenelitian ini bertujuan untuk mengetahui implementasi nilai-nilai Pancasila dalam membangun sikap disiplin pada siswa SMAN 1 Sekongkang. Metode penelitian yang digunakan pada penelitian ini yaitu metode kualitatif dengan pendekatan fenomologi yaitu melihat terhadap fenomena sosial yang terjadi dimasyarakat. Teknik pengumpulan data menggunakan tekhnik Obersvasi, wawancara, dan dokumentasi. Teknik analisis data yang digunakan adalah reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian implementasi nilai-nilai Pancasila dalam membangun sikap disiplin pada siswa SMAN 1 Sekongkang melalui: 1) Implementasi nilai-nilai Pancasila dalam membangun sikap displin pada siswa SMAN 1 Sekongkang pada nilai kemanusiaan dan nilai keadilan dimana siswa membudayakan sikap 5S baik terhadap guru dan teman, tidak saling membedakan antara ras, suku, agama, dan status sosial, serta mematuhi tata tertib disekolah , 2) faktor-faktor yang mempengaruhi dalam membangun sikap disiplin di SMAN 1 Sekongkang yaitu faktor eksternal yaitu dari dari segi lingkungan keluarga (kontrol orang tua), lingkungan sekolah, dan lingkungan masyarakat dan faktor internal yaitu dari segi kondisi jasmani (kelelahan) dan dari segi kondisi psikologis (perhatian, minat, dan motivasi).ABSTRACTThis study aims to determine the implementation of Pancasila values in building disciplined attitudes in SMAN 1 Sekongkang students. The research method used in this study is a qualitative method with a phenomenological approach, namely looking at social phenomena that occur in the community. Data collection techniques using observation techniques, interviews, and documentation. Data analysis techniques used are data reduction, data presentation, and drawing conclusions. The results of the research on the implementation of Pancasila values in building disciplined attitudes in SMAN 1 Sekongkang students through: 1) Implementation of Pancasila values in building disciplined attitudes in SMAN 1 Sekongkang students on human values and the value of justice where students cultivate 5S attitudes both towards teachers and friends, do not discriminate between race, ethnicity, religion, and social status, as well as comply with school rules. 2) the influencing factors in building discipline at SMAN 1 Sekongkang are external factors, namely in terms of the family environment (parental control), school environment, and community environment and internal factors, namely in terms of physical condition (fatigue) and in terms of psychological conditions (attention, interest, and motivation).
Abound Hepatic Mitosis: Unusual Morphology in the Intrahepatic Cholelithiasis Patient
Authors: Wang Yunjun , Jiang Lei , Wang Xiumei , Huang Qingxian , Wu Shishou , Yin Ying , Wang Jun , Pan Xubo , Yu Guohua
Published: February 2022

To explore the clinicopathological features of abound mitosis of the hepatocytes in intrahepatic cholelithiasis. The clinicopathological data of one case diagnosed as intrahepatic cholelithiasis was collected from Yantai Yuhuangding Hospital and the clinicopathological characters were discussed. A 68-year-old man suffered from the pain in the right upper quadrant and radiology showed multiple stones in the gallbladder and left liver. The images suggested intrahepatic cholelithiasis. The patient received gallbladder and partial hepatectomy. A large number of mitosis was observed and twelve nuclear fissions were found under high magnification, even in some area pathological nuclear fission could be observed in morphology. On the basis of detection in laboratory, the diagnosis of intrahepatic cholelithiasis was made. The patient did not receive any therapy after surgery. The patient was in a good condition after 18 months follow-up. Increased number of hepatic mitosis might be due to the stimulation from stones, hepatic biliary or secondary inflammatory. High index of proliferation should be prevented from the potential misdiagnosis of hepatic tumor.