bluuebunny/crossref_metadata_2025 huggingface dataset:
Accessory mineral thermobarometry, trace element chemistry, and stable O isotope systematics, Mooshla Intrusive Complex (MIC), Doyon-Bousquet-LaRonde mining camp, Abitibi greenstone belt, Québec
Authors: Neyedley K , Hanley J J , Zajacz Z , Fayek M
Published: October 2021

The Mooshla Intrusive Complex (MIC) is an Archean polyphase magmatic body located in the Doyon-Bousquet-LaRonde (DBL) mining camp of the Abitibi greenstone belt, Québec, that is spatially associated with numerous gold (Au)-rich VMS, epizonal
'intrusion-related' Au-Cu vein systems, and shear zone-hosted (orogenic?) Au deposits. To elucidate the P-T conditions of crystallization, and oxidation state of the MIC magmas, accessory minerals (zircon, rutile, titanite) have been characterized using a variety of analytical techniques (e.g.,
trace element thermobarometry). The resulting trace element and oxythermobarometric database for accessory minerals in the MIC represents the first examination of such parameters in an Archean magmatic complex in a world-class mineralized district.
Mineral thermobarometry yields P-T constraints on accessory mineral crystallization consistent with the expected conditions of tonalite-trondhjemite-granite (TTG) magma genesis, well above peak metamorphic conditions in the DBL camp. Together with textural observations, and mineral trace element
data, the P-T estimates reassert that the studied minerals are of magmatic origin and not a product of metamorphism. Oxygen fugacity constraints indicate that while the magmas are relatively oxidizing (as indicated by the presence of magmatic epidote, titanite, and anhydrite), zircon trace element
systematics indicate that the magmas were not as oxidized as arc magmas in younger (post-Archean) porphyry environments.
The data presented provides first constraints on the depth and other conditions of melt generation and crystallization of the MIC. The P-T estimates and qualitative fO2 constraints have significant implications for the overall model for formation (crystallization, emplacement) of the MIC and
potentially related mineral deposits.
Alkaline magmatism in the Selwyn Basin, Yukon: relationship to SEDEX mineralization
Authors: Scanlan E J , Leybourne M , Layton-Matthews D , Voinot A , van Wagoner N
Published: October 2021

Several sedimentary exhalative (SEDEX) deposits have alkaline magmatism that is temporally and spatially associated to mineralization. This report outlines interim data from a study of potential linkages between magmatism and SEDEX mineralization in the Selwyn
Basin, Yukon. This region is an ideal study site due to the close spatial and temporal relationships between SEDEX deposits and magmatism, particularly in the MacMillan Pass, where volcanic rocks have been drilled with mineralization at the Boundary deposit.
Alkaline volcanic samples were analysed from the Anvil District, MacMillan Pass, Keno-Mayo and the Misty Creek Embayment in the Selwyn Basin to characterise volcanism and examine the relationship to mineralization. Textural and field relationships indicate a volatile-rich explosive eruptive volcanic
system in the MacMillan Pass region in comparison to the Anvil District, which is typically effusive in nature. High proportions of calcite and ankerite in comparison to other minerals are present in the MacMillan system. Cathodoluminescence imaging reveals zoning and carbonate that displays
different luminescent colours within the same sample, likely indicating multiple generations of carbonate precipitation. Barium contents are enriched in volcanic rocks throughout the Selwyn Basin, which is predominately hosted by hyalophane with rare barite and barytocalcite. Thallium is positively
correlated with Ba, Rb, Cs, Mo, As, Sb and the calcite-chlorite-pyrite index and is negatively correlated with Cu. Anvil District samples display a trend towards depleted mid-ocean ridge mantle on a plot of Ce/Tl versus Th/Rb. Hydrothermal alteration has likely led to the removal of Tl from volcanic
rocks in the region.
Ongoing research involves: i) the analysis of Sr, Nd, Pb and Tl isotopes of volcanic samples; ii) differentiating magmatic from hydrothermal carbonate using O, C and Sr isotopes; iii) examining sources of Ba in the Selwyn Basin; iv) and constraining age relationships through U-Th-Pb
geochronology.
Effect of Selenium-Enriched Yeast Supplementation on Serum Thyroid-Stimulating Hormone and Anti-Thyroid Peroxidase Antibody Levels in Subclinical Hypothyroidism
Authors: Mahmoudi Leila , Mobasseri Majid , Ostadrahimi Alireza , Pourmoradian Samira , Soleimanzadeh Hamid , Kafili Behnam
Published: October 2021

Background:

In the subclinical hypothyroidism, T4 or T3 levels are normal and thyroid-stimulating hormone (TSH) is slightly high. Selenium deficiency can lead to thyroid dysfunction. The present study aims to investigate the effect of selenium supplementation on the thyroid hormone and anti-thyroid peroxidase antibody (anti-TPO AB) levels.

Materials and Methods:

In this double-blinded, randomized, placebo-controlled clinical trial, 42 patients with subclinical hypothyroidism were randomly assigned to receive 200 μg selenium or placebo for 8 weeks. In the both groups, the serum TSH and anti-TPO antibody levels were measured and assessed before and after the intervention.

Results:

After the interventions, the mean serum TSH reduction in the intervention and placebo groups was −10.98 ± 33.31 and −3.20 ± 38.36, respectively, which were not statistically significant. However, the mean serum anti-TPO Ab concentration increased in the intervention and placebo groups (109.81 ± 51.49% vs. 173.17 ± 96.26%), between which the difference was not statistically significant (P >0.05) despite a slight increase in the mean anti-TPO level in the intervention group.

Conclusion:

The results of the current study indicated that selenium supplementation has no significant effect on serum anti-TPO Ab and TSH levels in the patients with subclinical hypothyroidism. Studies with larger sample size and with different doses of selenium are needed to reach more precise results.
Antidepressant Compliance in Depression During the COVID Pandemic
Authors: Chakraborty Suhash
Published: October 2021

Background:

Depression epidemic is likely to follow the COVID pandemic. Depression is treatable if compliance is good. The study was aimed at identifying risk factors of poor antidepressant compliance during a pandemic.

Materials and Methods:

Sixty-four poor compliers of antidepressants during COVID period were compared with equal number of poor compliers of pre-COVID period on sociodemographic and clinical characteristics. The retrospective study was designed in a way to eliminate biases due to usual patient, social, or clinical factors. The hypothesis was that there would be some factors of antidepressant poor compliance exclusive to pandemic and these factors would be beyond the usual factors.

Results:

Majority (n = 43, 67%) of COVID period poor compliers were family members of employees. Subjects who came for prescription refill (n = 17, 27%) than consultation were poor compliant during COVID period. COVID period poor compliers (n = 6, 9%) were admitted less compared to pre-COVID counterparts (n = 15, 23%). COVID period subjects had mood symptoms predominant depression (n = 44, 69%) than physical symptoms (n = 20, 31%). The presence of death wish or suicidal ideas was significant (n = 16, 25%) in COVID period. Poor compliers of pandemic (n = 26, 41%) had more psychosocial stress (P < 0.05).

Conclusion:

The study did find some exclusive factors apart from doctor–patient relationship for good compliance. Depressive patients who perceive improvement in mood symptoms are poor compliers during pandemic. Compliance improves if patients find some primary purpose to come out during pandemic. Ongoing stress also reduces compliance.
Comparison of Psychiatric Morbidity and Quality of Life Among Caregivers of Substance Abusers
Authors: Kumar Pankaj , Chaudhary Rupesh , Bhalla Jasleen Kaur , Mishra B. P.
Published: October 2021

Background:

The effects of substance abuse are extended to primary caregiver who is vulnerable for psychiatric disorders and decreased quality of life (QOL).

Aim:

The aim of the study is to determine and compare the psychiatric morbidity and QOL in caregivers of various substance abusers (alcohol/opioid/alcohol + opioid dependence).

Methodology:

This cross-sectional study was conducted on caregivers of equal number of patients with alcohol/opioid/alcohol + opioid dependence presenting to Department of Psychiatry of a tertiary care center. The data were collected on sociodemographic parameters; psychiatric morbidity was assessed using the Mini-International Neuropsychiatric Interview (M. I. N. I.) questionnaire and the QOL was assessed by WHO-QOL BREF scale. Statistical analysis: The data were statistically analyzed on SPSS 21 software by using ANOVA, Chi-square, and Kruskal–Wallis tests.

Results:

Most of the caregivers were females. Out of 90 caregivers of each alcohol/opioid/alcohol + opioid dependence patients, 28.8% had dysthymia, 29% had major depression, 6.7% had social anxiety disorder, 13.3% had generalized anxiety disorder, 12.2% of the caregivers were found to have alcohol abuse, 15.5% of the caregivers were found to have substance abuse (nonalcohol), and 27% of the caregivers had no psychiatric morbidity. Deterioration of QOL was seen particularly in psychological and social domain. On comparing QOL, physical domain was affected adversely in caregivers of multiple substance abusers than alcohol dependence. On comparison among opioid dependence and multiple substance abusers, psychological, social, and environmental domains were significantly affected in the latter. The comparison among other pairs was insignificant.

Conclusion:

Substance abuse is a multidimensional problem which threatens the mental health and the QOL of the family member which needs to be addressed.
Hepatic Vein Thrombosis Secondary to COVID-19
Authors: Markanday Kushal , Bhardwaj Nitin , Radhakrishnan Buvana , Kumar P. Gopinath
Published: October 2021

COVID-19 is known to cause both arterial and venous thromboembolism. Although a lot of attention is being given to those presenting with myocardial infarction and stroke, splanchnic vein thrombosis which includes portal, mesenteric, splenic, and hepatic vein thrombosis is often underreported. A 21-year-old female presented with progressive abdominal distension and obstipation for the past 2 weeks. The patient was diagnosed as a case of moderate COVID-19 illness 2 weeks before the onset of these symptoms and recovered on receiving treatment according to the COVID protocol. Physical examination revealed pallor and bilateral pitting pedal edema up to ankles. Systemic examination revealed uniformly distended abdomen with signs of free fluid and tenderness in the right hypochondrium. Hematological investigations showed moderate-grade microcytic hypochromic anemia. Biochemically, indirect hyperbilirubinemia and transaminitis with moderately elevated D-dimers and Lactate dehydrogenase (LDH) was noted. Radiological imaging of the abdomen (including USG with doppler and CT contrast Scans) revealed gross ascites, nutmeg appearance of liver with completely obscured hepatic veins indicating no flow of blood, multiple intrahepatic portosystemic collaterals and a partially thrombosed inferior vena cava with no evidence of portal hypertension. All other workup to rule out other causes of hepatic vein thrombosis was inconclusive. The patient was treated with low-molecular-weight heparin and then continued with oral warfarin at discharge. On a 4-week follow-up, the patient showed marked clinical improvement with partial resolution of presenting symptoms.
Mass Screening of COVID-19 Cases by Sputum Testing
Authors: Saleem Sheikh Mohd , Ghatak Nishantadeb , Bhattacharya Sudip
Published: October 2021

SARS CoV 2 virus is detected in the respiratory tract by using nasal/oropharyngeal and nasal mid-turbinate swabs, nasopharyngeal wash and aspirate, and an oral aspirate. The anterior nares are the most common place to collect samples due to its ease and little invasiveness. Sample collection requires experienced hands, and if the appropriate technique isn't followed, it might lead to false negative results and alter the final conclusion. Because of its size and robustness, India's healthcare system has over 700 districts each running National Tuberculosis Elimination Program (NTEP) and experts in India have proposed modifying the CBNAAT machines used in NTEP program for COVID 19 testing by utilizing a new cartridge. After a second wave of COVID-19 cases, the number of cases in India is on the rise again. When dealing with a highly contagious disease, healthcare professionals are constrained by a lack of personal protective equipment, logistics, and infrastructure. The nasopharyngeal specimen and the procedure involved, make it a more difficult and riskier affair for healthcare practitioners to perform. If COVID-19 is combated with the NTEP's current infrastructure, human resources, and logistics, we believe that early detection of cases and overall containment will be maximized. Sputum samples can be self-collected in small plastic containers and sent to the nearest tuberculosis unit for CBNAAT analysis instead of using the professional technique of collecting nasopharyngeal swabs in Viral Transport Media. Sputum sample collection is a simple operation. Be it in urban tertiary care facilities or a rural subcentre. To collect sputum, healthcare staff can simply assist. In the current phase of the pandemic in India, where the majority of COVID-19 infections are asymptomatic, mass screening at the community level using effective testing specimens and methodologies becomes critical and the only choice. It would make sense to collect COVID-19 samples at the community level based on the scientific evidence in such a scenario, especially for a country with a population of over 1.3 billion people.
Evaluation of the Pediatric Antimalarial Prescriptions in a Teaching Hospital in Southeastern Nigeria
Authors: Mosanya Adaobi Uchenna
Published: October 2021

Background:

Malaria in Nigeria with the highest morbidity and mortality in children between 6 months and 5 years continues to be a disease burden. In line with the World Health Organization recommendation of diagnosis in all ages before treatment, Nigeria provided guidelines on parasite-based diagnosis. Therefore, in order to achieve its preelimination and the reduction of mortality caused by it to zero by 2020, it is necessary to assess the compliance of the prescribers to the guidelines.

Objectives:

The objectives of this study were to determine the cases who were diagnosed based on positive malaria parasite test and the level of compliance of the prescribers to the National Malaria Treatment Guidelines.

Methods:

A total of 3034 prescriptions of antimalarial drugs were collected between 2003 and 2011 in the Outpatient Department of the Pediatric Clinic. Data were analyzed using Microsoft Excel and SPSS V.20.0 and grouped into two: prepolicy (2003–2005) and postpolicy (2006–2011) periods. Descriptive and inferential statistics were used atP< 0.05 level of significance.

Results:

The study revealed that diagnosis based on positive malaria parasite test was 4.8% of 2765 patients. There was a noticeable increase in the prescription of artemisinin combination therapy in the postpolicy period (32.6%), but the compliance to the Antimalarial Treatment Guideline was low (23.8%).

Conclusion:

There was a high incidence of empirical diagnoses of malaria and treatment. Many of the artemisinin-based combination therapies prescribed were not recommended.
Heat Shock Protein 90α in Nipple Discharge as a Potential Tumor Marker for Breast Cancer
Authors: Wang Yan-Yan , Liu Can , Chen Xu , Ji Jian , Zhu Sheng-Lin , Sun Qi , Zhang Kai , Zhu Jiang , Zhao Song , Wang Ya-Wen , Ma Rong , Wang Jian-Li
Published: October 2021

Heat shock protein 90α (HSP90α) has been confirmed to be upregulated in the blood in various types of tumors and may therefore serve as a potential tumor marker. However, whether HSP90α exists in nipple discharge remains unknown, and its expression and diagnostic value in nipple discharge remain unclear. In this study, the expression of HSP90α, carcinoembryonic antigen (CEA), and cancer antigen 153 in nipple discharge and blood from 128 patients was measured. Receiver operating characteristic curve was used to assess the diagnostic value of HSP90α. Further, its relationship with clinicopathological parameters of patients with breast cancer was analyzed. The results showed that the expression of HSP90α in nipple discharge was significantly higher in patients with breast cancer than in those with benign disease, and its diagnostic value was better than that of CEA. Combination of HSP90α and CEA showed better diagnostic efficacy than HSP90α or CEA alone. Moreover, the expression of HSP90α displayed a stepwise increase from benign lesions, followed by carcinoma in situ to invasive ductal carcinoma. HSP90α was positively correlated with Ki67 expression. However, there was no significant difference in the expression of HSP90α in blood between patients with breast cancer and benign disease. Further, the expression of HSP90α was higher in nipple discharge than in blood. In summary, HSP90α was upregulated in the nipple discharge of patients with breast cancer, and it may be related to the occurrence and progression of breast cancer. HSP90α in nipple discharge may serve as a potential diagnostic marker for breast cancer.
Cytotoxic activity of flavonoid from local plant Eriocaulon cinereum R.B against MCF-7 breast cancer cells
Authors: Nugraha Arde Toga , Ramadani Arba Pramundita , Werdyani Sista , Pratiwi Isnaini Adinda , Juniardy Topan , Arfadila Sita , Mahardhika Muhammad Reza Putra
Published: October 2021

Eriocaulon cinereum R. Br is used as traditional medicine by the local community in Bangka Belitung Island, Indonesia. The plant is processed as an infusion for fever, boosts the immune system, and treats tumor cells. However, scientific research on this species is still limited. The aims of this study were to determine the cytotoxic of E. cinereum against MCF-7 cells. The results suggested that one of the compounds has a good cytotoxic activity. Therefore, it is quite promising in the effort of cancer drug discovery. The active compound has a flavonoid, which plays a role in several anticancer mechanisms. This study provided scientific evidence regarding the utilization of E. cinereum by the local community for cancer therapy. The plant can be further developed as an alternative agent to treat cancer or as cancer adjuvant therapy.
Quantitative determination of dexamethasone sodium phosphate in bulk and pharmaceuticals at suitable pH values using the spectrophotometric method
Authors: Al-Owaidi Mohammed Fanokh , Alkhafaji Sura L. , Mahood Abdulbari Mahdi
Published: October 2021

Dexamethasone sodium phosphate (DSP) is an ester of dexamethasone with anti-inflammatory action. This study provides new insights to develop a simple, precise, and accurate spectrophotometric method for the quantitative determination of DSP in bulk and pharmaceuticals. The method was validated before being applied to determine the DSP in six pharmaceutical injection forms from different companies. DSP is soluble in phosphate buffer, so it was used as a solvent, and a pH of 6 was found to be suitable for determination purposes. The DSP solution was scanned in the ultraviolet range (200–400 nm) using a double-beam spectrophotometer with a 1-cm quartz cell. The wavelength (λ max) of DSP was set at 242.5 nm, following the Beer–Lambert law for concentrations from 2 to 50 μg/ml. Dexa AIWA (Germany) showed the best results, being very close to the bulk value with no significant variation. Similarly, Dexamed (Cyprus) and HEMAZON (Syria) showed no significant differences from the bulk; however, the three remaining injections, DEXAKAL (India), DEXABRU (India), and DEXARON (China), showed significant variations from the bulk. Estimated limit of detection and limit of quantitation values for DSP were 0.83 and 2.5 μg/ml, respectively, with a regression coefficient of 0.999. Recovery studies were then used to determine the accuracy of the suggested method. The percentage of recovery was found to be 98.58%–102.52%. All results are suggesting a pivotal method for the routine analysis of DSP both in pure form and the commercially pharmaceutical forms.
Antihypertensive Activity of Combination of Anredera cordifolia (Ten.) V. Steenis and Sonchus arvensis L. Leaves on Epinephrine Induced Male Wistar Rat
Authors: Suliska Nova , Suryani  , Insanu Muhamad , Sukandar Elin Yulinah
Published: October 2021

In Indonesia, hypertension is a condition that can lead to death through stroke and TB. Herbs have traditionally been used in Indonesia as an alternative medicine for lowering blood pressure. The leaves of Anredera cordifolia and Sonchus arvensis have been investigated for their antihypertensive potential. Based on the number of treatments, rats were randomized into groups. Each group consists of five rats. The test animals were grouping as follows: the positive control group (hypertension induction without treatment), A. cordifolia 50 mg/kg b.w. group, A. cordifolia 100 mg/kg b.w., S. arvensis 50 mg/kg b.w, S. arvensis 100 mg/kg b.w., A. cordifolia 25 mg/kg b.w + S. arvensis 25 mg/kg b.w, A. cordifolia 50 mg/kg b.w + S. arvensis 50 mg/kg b.w, and atenolol 4.5 mg/kg b.w. The rats were given 0.25 mg/kg b.w. of epinephrine intraperitoneally. The initial, after induction, and final blood pressure of the animals were measured using the CODA® noninvasive blood pressure device. All animal test groups at T60 showed a significant difference in systolic and diastolic blood pressures to initial blood pressure (T0), P < 0.05. The combination of A. cordifolia 50 mg/kg b.w and S. arvensis 50 mg/kg b.w showed the highest percent inhibition of systolic and diastolic blood pressure. The combination of A. cordifolia and S. arvensis 50–50 mg/kg b.w showed the best effect of lowering systolic and diastolic blood pressure on the pathway of inhibiting adrenergic receptors.
Modulation of platelet functions by Careya sphaerica Roxb. leave extracts
Authors: Khobjai Warachate , Ninlaor Wanvisa , Watcharasamphankul Worawan , Thongom Thaksaorn , Sukati Suriyan
Published: October 2021

Platelets form a plug to prevent blood loss and contribute to wound healing. Kradonbok, Careya sphaerica Roxb., is a Thai plant with medicinal properties. Conventionally, leaves of C. sphaerica are being used to help wound healing in Thailand. The present study was aimed to investigate the effect of C. sphaerica on the function of platelet. Four different extracts of leaves of C. sphaerica (distilled water, methanol, ethanol, and chloroform extracts) were prepared. The extracts at 5.0 mg/ml per dose were tested for the effect of C. sphaerica on platelet adhesion and aggregation properties, by employing a microtiter plate approach. The phytochemical identification was done by using gas chromatography–mass spectrometry (GC-MS). Our data revealed that chloroform extract significantly activated thrombin-induced platelet adhesion (105.27 ± 0.11%, P < 0.05). None of the extracts exhibited an improvement in platelet aggregation. Further GC-MS analysis of the chloroform extract revealed five key phytochemical constituents with potential platelet activation properties. In conclusion, our study evaluated platelet activation and potentially wound healing property of C. sphaerica. GC-MS analysis identified potential bioactive phytochemical compounds in C. sphaerica which warrant further investigation to characterize these compounds.
Low-Velocity Flow Doppler Enhancement for the Study of Spontaneous Echo Contrasts
Authors: Thomas George
Published: October 2021

Detection of spontaneous echo contrasts (SEC) is important in assessing the risk of stroke and thromboembolism. Transthoracic echocardiography is the most widely used primary imaging for left ventricular SEC. Although harmonic imaging improves visualization to an extent, further improvement in the detection of the phenomenon is desirable. We are presenting images of two patients acquired with a novel method using Doppler to enhance the detection of SEC.
Effect of Activities of Daily Living on Quality of Life among Japanese Adults with Duchenne Muscular Dystrophy
Authors: Saotome Takako , Nojima Masanori , Iwase Satoru , Komaki Hirofumi
Published: October 2021

Objectives:

This study aimed to evaluate the relationship between activities of daily livings (ADLs) and psychological distress along with the quality of life (QOL) in Japanese adults with Duchenne muscular dystrophy.

Patients and Methods:

This study surveyed 36 adults using the Functional Independence Measure (FIM), the 36-Item Short-Form Health Survey (SF-36 v2) version 2.0, World Health Organization QOL-26, and Hospital Anxiety and Depression Scale.

Results:

No significant correlation was observed between the FIM scores and scores for all three scales (R < |0.2 | for every item).

Conclusions:

ADLs did not correlate significantly with psychological distress or QOL without considering independent demographic characteristic factors
The Influence of Wheel Rotations to the Lateral Runout of a Hybrid Material or Dimensionally Reduced Wheel Bearing Flange
Authors: Lee Inha , Callaghan Kevin , Lee Seonho (Athran) , Sutherlin Robert , Shim Heechan , Jang Boyoung , Assumpcao Douglas , Godinho Eduardo
Published: October 2021

The automotive industry is continuously striving to reduce vehicle mass by reducing the mass of components including wheel bearings. A typical wheel bearing assembly is mostly steel, including both the wheel and knuckle mounting flanges. Mass optimization of the wheel hub has traditionally been accomplished by reducing the cross-sectional thickness of these components. Recently bearing suppliers have also investigated the use of alternative materials. While bearing component performance is verified through analysis and testing by the supplier, additional effects from system integration and performance over time also need to be comprehended.

In a recent new vehicle architecture, the wheel bearing hub flange was reduced to optimize it for low mass. In addition, holes were added for further mass reduction. The design met all the supplier and OEM component level specifications. Vehicle testing, however, revealed that the wheel bearing developed high assembled lateral runout (ALRO) and judder. This was due to the tires and wheels being rotated multiple times during a durability schedule. Excessive ALRO will generate high disc thickness variation (DTV) which will lead to pulsation or judder complaints.

The root cause of the vehicle level judder was determined to be caused by excessive ALRO and DTV in the brake corner. The major contributor to this LRO issue was plastic deformation of the bearing wheel flange that occurred with use and multiple tire/wheel rotations.

This vehicle was validated in multiple regions of the world. Regional differences in vehicle service procedures were observed on the same architecture. Further investigation showed that the regions which performed more wheel rotations and other maintenance observed the vehicle judder, while the other region that did less maintenance did not.

To better understand the effect of bearing wheel flange geometry on ALRO in this condition, a lab evaluation was performed. Multiple wheel flange designs were evaluated, including bearing designs with different wheel flange thicknesses and versions with and without weight saving holes. Additionally, bearings with a hybrid aluminum/steel wheel flange were tested.
Pandora streaming radio
Authors: Lozić Joško
Published: October 2021

Razvoj interneta i digitalizacija proizvodnih procesa izravno su utjecali na radikalne zaokrete u menadžerskim strategijama medijske industrije. Nove medijske industrije razvijale su se usporedo s naglim tehnološkim napretkom te su rušile barijere koje su izgrađene u prošlom stoljeću. Streaming industrija dio je nove medijske industrije koja nastaje u 21. stoljeću, a već pokazuje znakove saturacije te se konkurenti udružuju kako bi zadržali i proširili tržišni udio. Cilj je ovog rada analizirati menadžerske strategije i način upravljanja platformom Pandora Media u kontekstu financijskog poslovnog rezultata. Analiza rezultata poslovanja ukazuje na gubitke koje Pandora Media ostvaruje iz operativnog poslovanja, ali i potpunu promjenu menadžerskih
strategija. Iako pripada obitelji novih medijskih industrija, odnosno nove menadžerske paradigme, Pandora Media vratila se u okrilje klasičnog
menadžerskog modela zadržavajući temeljna obilježja streaming industrije. Streaming industrija, iako jedna od najmlađih industrija unutar medijske industrije, već bilježi prve znakove zasićenja.
Treba li smanjiti ili povećati poreze u turizmu?
Authors: Endres Renata , Endres A. Bryan
Published: October 2021

Porez na dodanu vrijednost u turizmu ima ključnu ulogu u poticanju razvoja turizma, ostvarivanju konkurentne pozicije turističke destinacije te prikupljanju prihoda ostvarenih od turizma. Dosadašnjom izmjenom visine stopa poreza na dodanu vrijednost u turizmu hrvatska vlada nastojala je ostvariti konkurentnost hrvatske turističke destinacije, uz

maksimiziranje iznosa prihoda prikupljenih od turizma. U radu se upotrebljavaju sekundarni podaci za razdoblje od 1998. do 2020., a cilj je rada analizirati alternativan pristup oporezivanju smještaja i ugostiteljstva, sličan onome koji primjenjuje SAD, da bi se ostvarili bolji fiskalni i ekonomski učinci. U rezultatima analize prikazuju se prednosti i nedostaci povišene i snižene stope poreza na dodanu vrijednost u turizmu Hrvatske, odnosno turističkih poreza SAD-a.
Upravljanje znanjem u funkciji individualnog i profesionalnog razvoja zaposlenika
Authors: Zoretić Gordana , Čižmek Vuković Ondina , Radovanić Helena
Published: October 2021

U suvremenom svijetu okruženje je vrlo dinamično i promjenjivo pa se svaka organizacija tijekom svoga postojanja suočava s izazovom: kako se čim prije i uspješnije prilagoditi zahtjevima nacionalnog i svjetskog tržišta. Organizacijama su stoga, kao nužnost dugoročnog

opstanka na tržištu, ključni njezini zaposlenici. Njihovo se znanje i sposobnosti te vrijednosti i prepoznatljivost kojima organizacija raspolaže mogu pretvoriti u vrijednost na tržištu. Za kontinuirano stvaranje vrijednosti iznimno je važno ulaganje u individualni i profesionalni razvoj zaposlenika, odnosno u ljudski potencijal. Stoga bi
proces upravljanja znanjem neminovno trebao rezultirati poboljšanim kompetencijama zaposlenika, odnosno povećanjem njihove proaktivnosti, originalnosti, kreativnosti i fleksibilnosti. Učinkovito upravljanje ljudskim potencijalom te suradnja menadžmenta i zaposlenika vrlo je složen proces u kojem se od menadžmenta očekuje da utječe na zaposlenike, da stvara i potiče kulturu učenja, rada, razvoja i dijeljenja znanja te inovativnosti i komunikacije pri čemu se trebaju usuglasiti interesi zaposlenika i interesi organizacije.
Poder y Sacralización del Paisaje en los Andes Centrales: Una aproximación
Authors: Lobaton Carlos Farfán , Canales Victoria Aranguren
Published: October 2021

Este articulo está basado en estudios realizados en los andes centrales, principalmente lo que corresponde a los departamentos de Lima, Ancash y Junín, logrando identificar asentamientos   prehispánicos en estrecha relación a los asentamientos actuales, articulados a una geografía sagrada claramente identificada por la gran mayoría de las comunidades actuales. Esta sacralidad del paisaje obviamente se remonta a la época prehispánica y en muchos de los casos tienen su continuidad en la memoria de las comunidades actuales donde se guarda la esencia fundamental de su origen. Para entender esta sacralidad y la sacralización, identificamos los indicadores conceptuales que sostienen lo sagrado en el pensamiento del hombre tomado en cuenta los conceptos ontológicos de lo sagrado y lo profano y su relación con el paisaje socializado. Cuando lo sagrado y lo simbólico es manipulado por los grupos de poder, entonces la sacralidad y la sacralización también son asumidas como mecanismos de control, no solo de lo ideológico, sino también la apropiación territorial, control de los sistemas de producción, de la acumulación de riqueza basada en ofrendas y tributos. Por ello nuestro propósito es de alguna manera aproximarnos a identificar y aislar algunos de los rasgos y factores causales del proceso de sacralización del paisaje tomando en cuenta el segmento de tiempo transcurrido desde su origen.

This article is based on studies carried out in the central Andes, mainly in the departments of Lima, Ancash and Junín, identifying pre-Hispanic settlements in close relation to the current settlements, articulated to a sacred geography clearly identified by the great majority of the current communities. This sacredness of the landscape obviously dates back to pre-Hispanic times and in many cases has its continuity in the memory of the current communities where the fundamental essence of its origin is kept. To understand this sacredness and sacralization, we identify the conceptual indicators that sustain the sacred in human thought, taking into account the ontological concepts of the sacred and the profane and their relationship with the socialized landscape. When the sacred and the symbolic are manipulated by power groups, then sacredness and sacralization are also assumed as mechanisms of control, not only of the ideological, but also of territorial appropriation, control of production systems, of the accumulation of wealth based on offerings and tributes. Therefore, our purpose is to identify and isolate some of the features and causal factors of the process of sacralization of the landscape, taking into account the segment of time elapsed since its origin.
Commodification of Children on Social Media Endorsement (Case Study on @zaskiaadyamecca’s Instagram Account)
Authors: Akmalia Nurul , Ardiani Septia
Published: October 2021

This study explores how commodification practices occur through promotional uploads or commonly known as endorsements on social media accounts of public figures (influencers). Influencers, as people who are considered capable of influencing the audience, take advantage of this fame to carry out promotional practices that involve their families, even their children. This economic practice is not only considered as exploitation, but is specifically known as the commodification of children. The presentation of this research was carried out using a case study approach on one of the Instagram influencer accounts, Zaskia Adya Mecca. Uploads on her Instagram with handle called @zaskiaadyamecca were analyzed using the social semiotics method with derivatives of visual communication analysis tools. Document studies were also conducted on Zaskia's promotional or endorsement fee involving her family and children. This information is secondary data to provide validation for arguments regarding commodification practices communicated visually through Instagram. The results of the research based on visual communication and document studies are that the practices on the Instagram account is indicated to be commodifying children.
The Design of Augmented Reality-Based Synectic Model Device in Writing Short Stories
Authors: Damayanti Deasy Aditya , Nurwahidah Lina Siti , Hamdani Agus , Hasim Abdul
Published: October 2021

A Short story is a miniature of people's experience while the characters, plot, and setting aim to record imaginative events (Stanton, 2017). When making up story ideas, students have problems developing story facts such as plot, characters, and settings (Sayuti, 2006). This barrier emerged conflicts that were unevenly distributed across all stages of the course. The direct characterization employed in storytelling made the short stories less varied. The physical and setting depicted did not work out optimally. The advantage of using the synectic model is that it can allow students to look for and makeup concepts to describe objects through an analogy process. Augmented Reality allows users to interact with an object's interface and see it in a well-designed and attractive 3D format, so it can solve student difficulties in developing story ideas in writing short stories.
Impact of Training and Goal Setting on Employee Engagement and Commitment in Banking Sector of Pakistan
Authors: Ali Amir , Zengtian Zhang , Amoah Mavis , Grace Grace
Published: October 2021

Purpose: This study aimed to explore the effect of training and goal setting on employee engagement and commitment in the banking sectors of Hyderabad, Pakistan.
Approach/Methodology/Design: The collection of information was acquired using a closed-ended questionnaire with a Likert scale. The convenience sampling method was used, and 270 respondents participated in the survey. The data was analyzed by using Statistical Package for Social Sciences (SPSS).
Findings: The findings revealed that training and goal setting can boost employees’ engagement and commitment in the banking sectors of Hyderabad, Pakistan.
Practical Implications: The suggested model in the study can be executed in almost any organization to increase the overall engagement and commitment of employees. For the model to be implemented effectively, a decent time has to be devoted to the goal settings, as it is the most integral and critical phase towards this whole organizational system. Each factor in this theoretical framework must also give as much information as needed to collaborate on it to achieve the goal of organization. This model can be used, in specific, in the services industry, to achieve their ultimate strategic goals.
Originality/value: This research provides empirical support for developing management programs that promote employee training and goal setting, leading to employee engagement and commitment. This study is important for academia, professionals, and scholars alike.
Role of Magnetic Resonance Angiography in Evaluation of
Brain Pathologies
Authors: Srinivas Varakala , Rammohan Sai Venkata
Published: October 2021

Background: MR angiography is the latest technique for the
evaluation of cerebrovascular diseases. It is now used
commonly for the evaluation of brain pathologies. The
advantage is it is a non-invasive method of brain vasculature.
The present study aimed to evaluate the role of Magnetic
Resonance Angiography in the detection of brain pathologies
and to study the Role of Magnetic Resonance Angiography in
Cerebral Arteriovenous Malformations, Aneurysms, and
Cerebral infarctions.
Methods: Data for the study was collected from patients with
clinically suspected cerebral lesions or from patients, in whom
previous images depicted cerebral lesions, undergoing MRA
for evaluation of cerebral lesions Patients underwent MR
imaging including TOF Magnetic resonance angiography
according to the set protocols after obtaining informed
consent. All these patients had undergone detailed clinical
evaluation by the referring neurosurgery unit.
Results: In this study, a total of n=32 cases were included out
of which n=6(18.75%) were AVM, n=10(31.25%) were
Aneurysms, and n=16(50%) were cases of infarcts. Of the total
n=16 infarct cases n=8(50%) were found in the middle cerebral
artery (MCA) n=4(25%) in ACOM and n=2 in PCOM, as well as
Internal carotid artery (ICA). Of the MCA cases n=5(62.5%) were
right-sided and n=3(37.5%) were left-sided.
Conclusion: MRA is now in routine use as a non-invasive tool
for imaging the cerebralvasculature. In cerebrovascular disease,
it is the investigation of choice forpatients who are suspected/
increased risk of having unruptured intracranial aneurysms,
and intracranial vascular disease associated with acute
infarction ,intracranial dissection of the carotid and/or
vertebral arteries, and follow up cases of Cerebral AVMs.
Endüstri 4.0 Çağında Yükseköğretim Kurulumları İçin Tedarik Zinciri Yönetiminde Bir İş Zekâsı Karar Destek Sistemi Uygulaması
Authors: DAMAR Muhammet
Published: October 2021

Türkiye’de 2021 yılına gelindiğinde iki yüzün üzerinde üniversitenin eğitim ve öğretim faaliyeti gösterdiği görülebilir. Yükseköğretim kurumları Türkiye’nin barındırdığı genç nüfus da dikkate alındığında ülke geleceği için kritik ve önemli bir noktada yer almaktadır. Bu anlam üniversite kavramının tarihsel süreç içerisinde geçirdiği dönüşüm ve günümüzdeki kritik değeri değerlendirildiğinde ne kadar önemli olduğu görülebilir. Fakat son yıllarda hızla açılan yeni üniversiteler, Türkiye’nin gelişmekte olan kıt kaynaklara sahip bir ülke olduğu gerçeği, yükseköğretim kurumlarında bütçe yönetimini ve harcamaların etkin kullanımının önemini daha da ortaya koymaktadır. Çalışma bu amaçla, bir üniversitelerin satın alma süreçleri için bir karar destek modeli ortaya koymakta ve uzun süre satın alınan ve farklı birim harcamalarının etkin yönetimi için iş zekası modelini çözüm olarak sunmaktadır. Ortaya konulan çalışma bir üniversite için uygulanabilirliği üzerine kurgulanmış ve demo veriler ile gerçekleştirilen raporlama aracı ile olası kazanımları üzerinde bir değerlendirmede bulunulmuştur. Çalışma bu yönüyle kendi gelirleri ile birlikte kamu bütçesinden faydalanan yükseköğretim kurumlarının etkin bütçe yönetimine dikkat çekmektedir. Gerçekleştirilen uygulamanın kamu kurumlarının hem iç hem de dış denetim süreçleri için bilişim sistemlerinin etkin kullanımı için örnek teşkil edecektir. Literatürde gerçekleştirilen ulusal ve uluslararası tartışmalar ile yükseköğretim kural koyucularının iş zekası gibi güncel teknolojileri kullanarak nasıl daha etkin veri analizi yapabileceği ve veri yönetimi ile etkin kurum yönetimi sağlanabileceği hususunda değerlendirme sunmaktadır.
The Effect of Microwave-Assisted Alkali and Xanthomonas t ranslucens ICBB 9762 for Rice Straw Pretreatment on Electricity Generation of Microbial Fuel Cell Inoculated by Staphylococcus saprophyticus ICBB 9554
Authors: Khoirunnisa Nur Syafira , Anwar Syaiful , Santosa Dwi Andreas
Published: October 2021

Rice straw can be utilized as an organic substrate in Microbial Fuel Cell (MFC) to generate electricity by microbes as a biocatalyst. This research was aimed to observe the effect of Xanthomonas translucens ICBB 9762 inoculation pretreatment on microwave-assisted alkali treated rice straw on the lignocellulosic structure change of rice straw and to observe the performance of MFC system fed by treated rice straw. The stages of research included: (1) pretreatment of rice straw through microwave-assisted alkali and Xanthomonas translucens ICBB 9762 inoculation, (2) observation of MFC performance including electrical voltage; electrical current; power density; and Coulombic efficiency, and (3) anolite analysis including COD removal, pH and Eh. The result showed that rice straw was successfully decomposed by inoculation of Xanthomonas translucens ICBB 9762 on microwave-assisted alkali pretreatment which the highest cellulose yield about 29.36 %. Treated rice straw produced better performance than rice straw without pretreatment which the best performance resulted by the combination of Xanthomonas translucens ICBB 9762 inoculation and microwave-assisted alkali pretreatment which produce electrical voltage, electrical current, and power density value of 337.90 mV, 0.39 mA, and 26.20 mW/m2, respectively. The utilization of solid substrate such as rice straw need more attention due to there was COD enhancement while in COD reduction reach COD removal efficiency and coulombic efficiency ranged 5.15 - 54.08 % and 0.25 - 7.83 %, respectively.
HIGHLIGHTS

Microbial Fuel Cell fueled by lignocellulose substrate, which is rice straw
Lignocellulose structure deconstruction through microwave-assisted alkali pretreatment
A combination of microwave-assisted alkali and cellulose-degrading bacteria inoculation pretreatment for rice straw generate the highest electricity
Electricity generation improvement in microbial fuel cell through mix culture between cellulose-degrading bacteria and exoelectrogen bacteria
Cellulose degrading bacteria increase Chemical Oxygen Demand (COD) due to the solubility of low molecular weight organic compounds increasing during microbial fuel cell incubation
Universo encriptado en el entretejido simbólico de una mesa alemana del siglo XVI
Authors: Aja Pérez María del Pilar
Published: October 2021

Heavenly Universe es una obra compleja de gran erudición y con múltiples simbolismos encriptados. Los astros, los paisajes y los personajes con sus atributos están inmersos en el contexto histórico de la Alemania del siglo xv1, por lo que el análisis de este entretejido simbólico resulta fundamental. Tanto los mitos de hilos y redes como la luz central en el plano cosmoló­gico, aludirán a esta obra que Martin Schaffner encriptó en la cubierta de una mesa: la joya más preciada del Universo, relacionada con la alquimia y el papel del artista.
COVID-19 Associated Acute Necrotizing Pancreatitis with Normal Serum Amylase and Lipase Levels: Report of an Unusual Finding
Authors: Sudarsanam Hemanth , Ethiraj Dillibabu , Govarthanan Navaneetha Kumar , Kalyanasundaram Srinivasan , Chitra Sathya Arunachalam , Mohan Saisurendar
Published: October 2021

Coronaviruses are a large family of single-stranded RNA viruses infecting humans and animals, causing a multitude of symptoms. COVID-19 is not only known to affect the respiratory system, but shows unusual gastrointestinal complications. Pancreatitis can be caused by biliary stones, alcohol abuse, viruses, drug intake, metabolic syndromes, or trauma. Diagnosis of acute pancreatitis requires any two of the three criteria: acute onset of severe upper abdominal pain, consistent with pancreatitis; elevation of serum amylase or lipase, three times the upper limit of normal; and/or characteristic imaging findings. COVID-19 associated pancreatitis is thought to be mediated by the angiotensin-converting enzyme-2 receptor on the host cells, which are highly expressed in the pancreatic cells. Here, we report a unique case of acute necrotizing pancreatitis caused by COVID-19 with hyperglycemia and normal amylase and lipase levels.
Treppengeometrie.
Authors: Nekola Vladimir
Published: October 2021

Die Gestaltung von Treppen und Treppenräumen war schon immer eine der wichtigsten Aufgaben bei der Planung und Realisierung von baulichen Anlagen, auch wenn sie oft nachlässig und wenig fachmännisch behandelt wurden. Die Ästhetik von Treppen gründet sowohl auf ihrer Geometrie als auch auf der Konstruktion und Materialwahl. Das vorliegende Werk behandelt die Geometrie und die konzeptionellen Aspekte von Treppenanlagen. Neben detaillierten Angaben zu Steigungsverhältnissen, Podestformen und -lagen, zum gestalterisch ansprechenden Verlauf von Knicklinien und zur Terminologie beinhaltet dieses Buch auch die geometrisch anspruchsvollen Verziehungsverfahren der Stufen bei gewendelten Treppen. Drei Kapitel sind eigens der Formgebung von Wendel- und Spindeltreppen gewidmet.
Staub auf Baustellen.
Authors: Rühl Reinhold
Published: October 2021

Staub auf Baustellen wird häufig als unvermeidlich betrachtet, oft kann er jedoch gefährlich sein. Bei Arbeiten in geschlossenen Räumen sind die Staubkonzentrationen oft so hoch, dass Gesundheitsschäden wie Silikosen, Nasen- und Lungenkrebs drohen. Dieses Buch zeigt, dass es meist staubarme Arbeitstechniken gibt und es fast immer möglich und erschwinglich ist, staubarm zu arbeiten.

Dazu werden sowohl die Probleme mit Staub und Erkrankungen durch Staub auf Baustellen erläutert als auch die aktuellen Staubthemen wie Titandioxid, Asbest in Putzen, Fliesenklebern und Spachtelmassen, Nano sowie Feinstaub aus Dieselmotoren behandelt. Der Schwerpunkt des Buches liegt bei Stäuben, die beim Bauen, Renovieren und Reinigen auftreten. Betrachtet wird der Staub vor allem aus Sicht des Arbeitsschutzes auf der Baustelle.