bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of Insecticidal Efficacy of Two Leaf Powders for Control of Khapra Beetle, Trogoderma granarium (Everts) (Coleoptera: Dermestidae) in Wheat Grains
Authors: Oboho D.E. , Udofia L.E. , Ogbuke E. , Aina S.A. , Bassey E.B. , Okwor J.I. , Nelson A.U. , Akpan A.U. , Essience R.A.
Published: April 2024

Experiment was conducted to evaluate the efficacy of leaf powders of Senna mimosoides and Datura alba for the control of khapra beetle, Trogoderma granarium on stored wheat grains. Twenty 0-3 days old unsexed adults of T. granarium were introduced into each cup containing 20g of grains and covered with muslin cloth to allow aeration and prevent exit or entry of insects. The powders were applied at 5, 10 and 15% concentrations to study mortality, repellency and seed weight loss. The experiment were laid out in a Completely Randomized Design (CRD) of 5 by 4 (5 treatments and 4 replicates) including standard and experimental controls under laboratory conditions (28±2oC; 74±5% RH) for 28 days. Data obtained were analyzed using Analysis of Variance and means were separated using Turkey’s post hoc test. Both powders showed the presence of alkaloids, saponins, cardiac glycosides, flavonoids, phenols and tannins to which insecticidal properties can be attributed against T. granarium. There was an increase in mortality with the days of exposure in all concentrations with leaf extract of i + D. alba being more effective at 15% (1.25± 0.50) when compared with the control. Also, the powders of S. mimosoides + D. alba at various concentrations exhibited the highest repellency (90%) activity followed by those of S. mimosoides and D. alba separately. The seeds treated with cocktail of the powders gave the lowest seed damage, followed by that of S. mimosoides and D. alba when compared to the experimental control. The results indicated that powders used as sole or cocktail significantly (p<0.05) reduced insect populations and offered greater protection and high repellency compared to the control. Since S. mimosoides and D. alba powders are affordable for small farmers and environmentally safe, they ought to be promoted for use against khapra beetles. This is because they can be used as an alternative to synthetic pesticides in integrated pest management.
Assessment of House Cricket (Acheta domesticus) Meal for Nigerian Households
Authors: Omogunloye-Adeoye O.A. , Owagboriaye F.O. , Fafioye O.O. , Lawal O.A
Published: April 2024

Over 100 million people in Africa are affected by protein malnutrition because they cannot afford conventional animal protein. The light yellowish-brown cricket (Acheta domesticus) is one of the cricket species preferred for mass rearing. The study was aimed at assessing the safety of the house cricket meal for human and animals’ consumption in Nigeria. Four house crickets were collected from the wild and reared in the animal house of Olabisi Onabanjo University, Ago-Iwoye, Ogun State, Nigeria to produce several generations. Samples of adult and nymph house crickets were obtained from the stock and processed by sun-drying for three days and then analysed for microbial count. Samples of 10 g each were weighed and put in 90 ml of 4% tween 20 in 1 in 10 dilutions. Also, 10 ml was also measured aseptically and transferred to 90 ml of diluent in 1 in 100 bottle. The total aerobic microbial count for adult and nymph house cricket yielded growth with flat opaque colonies of Bacillus sp of 2430 cfu/g and 590cfu/g respectively. The mold count for the adult was 2470 cfu/g and 425 cfu/g for nymph respectively. House crickets sampled were free of diseasecausing microbes such as Escherichia coli, Staphylococcus aureus, Bacillus cereus, Clostridium perfringes and yeast.
Ancillary Services in Germany: Present, Future and the Role of Battery Storage Systems
Authors: Pant Prashant , Hamacher Thomas , Perić Vedran S
Published: March 2024

The growing integration of renewable energy sources poses significant challenges to the existing power system infrastructure. These challenges include reducing power system inertia, resulting in faster dynamics and deterioration of frequency stability margins. Additionally, the limited capacity of power electronics-based inverter units reduces the sources of reactive power generation, jeopardizing voltage stability. To address these issues, system operators are increasingly required to procure ancillary services to ensure reliable power system operation. This paper presents a comprehensive literature review of the current state of the ancillary services market in Germany, examining the various procurement schemes currently employed and the economics of services. It also highlights the insufficiency of existing ancillary services and identifies potential services that may be necessary to stabilize Germany’s future power systems, particularly as renewable energy sources continue to gain prominence. Furthermore, the paper explores the current status of battery storage technology in Germany and highlights its potential to provide ancillary services across different time resolutions. This review aims to benefit academics, researchers, practitioners, and policymakers by enabling them to make informed decisions and effectively navigate the changing energy landscape in Germany.
Dispersos y diversos: Propuesta exploratoria para educación remota de emergencia inclusiva en la ruralidad
Authors: Cordero González Yeimy Paola
Published: April 2024

La pandemia del SarCov2 – Covid 19- supuso por el aislamiento social un reto pedagógico y didáctico para el sistema educativo en los ámbitos públicos y privados. En la ruralidad el impacto fue agravado por las brechas, social y digital; de allí que en la mayoría de países latinoamericanos se improvisó con la educación remota de emergencia. El propósito de la investigación fue establecer una propuesta pedagógica social evaluativa para población regular y diversa mediante atención remota como aporte evaluativo en básica secundaria.

El trabajo es importante por estudiar propuestas evaluativas para población diversa y dispersa en entornos rurales caracterizados por la falta de criterios en competencias digitales ligados a las prácticas de aula. El marco teórico se estructura alrededor de las pedagogías críticas (Deleuze, 2012, citado en: Sáez Rueda, 2018), las pedagogías decoloniales y las epistemologías del sur, focos epistémicos de autores que han reflexionado sobre la esencia de la aesthesis decolonial en los entornos educativos, y la insumisión epistémica de De Sousa Santos (2014) y Mignolo (2019). El diseño metodológico optó por un modelo epistémico estructuralista, el paradigma del análisis crítico del discurso y el multimétodo, con 272 sujetos de investigación conformados por estudiantes, docentes y directivos docentes. Entre los resultados y conclusiones, de este trabajo destacan: la importancia del diagnóstico en competencias digitales para construir una propuesta. La metacognición creativa como base de una evaluación para población diversa y dispersa.
Efecto del proyecto ECHO en la desmonopolización de la atención médica
Authors: De la Calle Andrade Lucila Jazmín , Barba Maggi María Angélica , Choca Alcoser Edwin Gilberto , Gualpa Jaramillo Guillermo Gonzalo , Calderón Barba Erika Valeria , Yépez Hidalgo Francisco
Published: April 2024

Health goes through constant transformations, technological development being part of this phenomenon. In this sense, the teleclinic sessions of Project ECHO are a virtual training model, which allows direct advice to professionals who work on the first line of care. Objective: To demonstrate the positive effect of the application of the ECHO Project methodology, in the demonopolization of medical care, mainly in rural areas, from the perspective of the professionals involved in this program in Ecuador. Methodology: A quantitative, descriptive, crosssectional, field and non-experimental study was carried out. Through the ZOOM platform, clinical cases from various medical specialties were presented. Using free digital support, a survey questionnaire was applied to 102 participants, structured in 15 dimensions. 48 professionals completed a knowledge test composed of 40 questions. To calculate the positive responses, the values were ordered from highest to lowest. In the general measurement of the answers, the relative frequencies or percentages were included. Results: From the perception of the participants, 86.86% recognized that the teleclinic meetings deployed in the context of the ECHO Project have had an affirmative influence on the development of their activities, especially those associated with autonomous development. 68.50% of answers were correct in the test applied. Conclusions: Developing the teleclinic sessions, a positive effect has been obtained on the autonomy, independence and solvency of professional practice, contributing to the demonopolization of medical care.
Becoming a SoTL Scholar
Authors: Chick Nancy
Published: April 2024

The scholarship of teaching and learning (SoTL), a multidisciplinary field that focuses on systematic investigation in teaching and learning, is now over 30 years old. No longer just a grassroots movement of individual faculty committed to taking teaching and learning seriously, SoTL has become professionalized. Becoming a SoTL Scholar maps out what it looks like to be a SoTL scholar and how to get there by design. Becoming a SoTL scholar involves reckoning with one’s academic identity, since SoTL occupies a kind of “borderland” or liminal space outside of traditional disciplines. For faculty members who become interested in SoTL, this new space is typically disorienting at first, as the scholar grows from these initial moments to ultimately finding a place in the SoTL community. This book explores what happens after that phase, after one has come to embrace the identity of a SoTL scholar. It describes the traits that determine one’s credibility and expertise as a SoTL scholar, and delves into the ongoing collaborations, research groups, and networks that form much of that necessary SoTL community. The book also explores the possibilities for students and early-career colleagues who choose SoTL as their primary career path. Additionally, at the other end of the spectrum, our book also addresses how mid- and later-career SoTL scholars might maintain meaningful engagement and make lasting contributions to the field. Ultimately, Becoming a SoTL Scholar illustrates the different entry points offered by SoTL and provides inspiring narratives, practical advice, and aspirational proposals for the different aspects of being a SoTL scholar.
You’re Here! Now What? A Taxonomical Pathway for Sustained SoTL Research Engagement
Authors: Paul Jeff , Seniuk Cicek Jillian , Rodrigues Renato B.
Published: April 2024

“You’re Here! Now What? A Taxonomical Pathway for Sustained SoTL Research Engagement” by Jeff Paul, Jillian Seniuk Cicek, and Renato Bezerra Rodrigues presents a taxonomy for SoTL as a tool for developing a SoTL research agenda. Since the taxonomy was derived from a systematic review of the literature, the authors describe how it maps the field, while also acknowledging that a taxonomy may be too reductionist for some readers and too holistic for others. Ultimately, they argue that such a taxonomy provides a common language within SoTL, thus building understanding and connecting studies across the breadth and depth of the field.
ANALISIS KESIAPAN PELAKU UMKM KOTA BIMA MENGHADAPI INDUSTRI 4.0
Authors: Muhajirin
Published: March 2024

Penelitian ini adalah penelitian deskriptif, yaitu penelitian yang dilakukan untuk mengetahui bagaimana kesiapan pelaku UMKM yang ada di Kota Bima dalam menghadapi Revolusi Industri 4.0. Data penelitian dioleh dari hasil pengisian kusioner sebanyak 50  pelaku UMKM. Dari hasil penelitian, diperoleh secara umum pelaku UMKM di Kota Bima sudah siap dalam menghadapi Revolusi Industry 4.0. Hal itu ditandai dengan terdapat 86% pelaku UMKM yang sudah menggunakan internet maupun teknologi dalam menjalankan usahanya, seperti pada aspek produksi, pemasaran, laporan keuangan, sistem pembayaran dan lainnya, sementara itu masih 14% pelaku UMKM masih menjalankan usaha secara manual. Kesiapan UMKM juga ditandai juga dengan melihat berbandingan pada nilai thitung = 40,519 >  dengan ttabel = 1,677. Hal yang sama juga dilihat dari nilai Sig. (2-tailed) = 0,00 < signifikasi = 0,05. Dari perbandingan nilai statistik tersebut, maka pelaku UMKM di Kota Bima sudah siap dalam menghadapi perkembangan teknoogi atau yang disebut Revolusi
Iniquidades em saúde relacionadas à anemia falciforme: relato de experiência
Authors: Freitas Ana Carolina Santos , Nogueira Hiury da Silva , Peixoto Maria Fernanda de Almeida , Hannum Renato , Matias Karolina Kellen
Published: April 2024

Este relato de experiência aborda a prática relacionada à disciplina Estágio I ofertada no primeiro período do curso de Odontologia da Pontifícia Universidade Católica de Goiás (PUC Goiás). Prática essa que ocorreu no Laboratório de Análises Clínicas da PUC Goiás, no qual os estudantes do primeiro período foram incentivados a conversar com pacientes ali presentes na sala de espera acerca de determinantes da saúde e da saúde bucal. Dentre as diversas histórias compartilhadas entre estudantes e pacientes, uma se destacou pelas particularidades inerentes às iniquidades enfrentadas pela família, bem como pela doença que acomete a criança, que é a anemia falciforme. Tal doença provoca deformações dos glóbulos vermelhos do sangue. E, devido sua situação debilitada e determinantes sociais, apresenta diversos problemas que afetam à saúde bucal, como o acúmulo de bactérias na boca que ocasionaram cáries e perdas dentárias.
PROFIL PENGGUNAAN OBAT ANTIDIARE PADA BALITA DI PUSKESMAS LURAH CIREBON PERIODE BULAN JANUARI – DESEMBER 2019
Authors: Kunaedi Aan , Hidayati Nur Rahmi , Hasanah Amna Nur
Published: March 2024

Peningkatan angka pasien diare setiap tahunnya pada puskesmas Lurah Cirebon, tentunya perlu menjadi perhatian khusus terhadap penyakit ini, dimana penelitian ditujukan untuk mengetahui profil penggunaan obat antidiare pada balita di Puskesmas Lurah Cirebon periode Januari – Desember 2019. Dengan menggunakan rancangan studi retrospektif, menggunakan resep pasien untuk melihat pola pengobatan pasien balita pada Puskesmas Lurah Cirebon, didapatkan karakteristik pasien, dan profil penggunaan obat antidiare selama periode bulan Januari hingga Desember 2019. Dari hasil telaah resep periode tersebut didapatkan hasil dan kesimpulan : Umur yang memiliki jumlah kasus terbanyak adalah usia 0-12 bulan yaitu sebanyak 74 kasus (30,84%), Jumlah penderita diare balita terbanyak berjenis kelamin laki – laki 138 kasus (57,5%), Jenis obat antidiare yang paling banyak digunakan adalah zinc 2.300 tablet, dosis obat dan aturan pemakaian obat dalam pengobatan yang dilakukan untuk mengatasi penyakit diare pada balita di Puskesmas Lurah sudah sesuai dengan pedoman MTBS kecuali oralit tidak sesuai dengan MTBS
UJI AKTIVITAS ANTIDIABETES EKSTRAK N-HEKSANA, ETIL ASETAT, ETANOL DAUN POHPOHAN (Pilea trinervia Wight.) PADA MENCIT YANG DIINDUKSI ALOKSAN
Authors: Suhendy Hendy , Mutaafifah Siti , Nofianti Tita
Published: March 2024

Diabetes melitus merupakan suatu penyakit kelainan metabolik yang ditandai dengan tingginya kadar glukosa darah. Pengobatan diabetes dapat dilakukan melalui pengobatan tradisional yang berasal dari alam seperti daun pohpohan (Pilea trinervia Wight.) yang mana dapat meminimalisir efek samping dari pengobatan konvensional. Tujuan dari penelitian ini adalah untuk mengetahui dosis dengan perbedaan pelarut terbaik dalam penurunan angka glukosa darah. Induksi menggunakan aloksan dengan mencit sebagai binatang percobaannya. Pengecekan kadar glukosa darah puasa dilakukan pada hari ke 0, 7, dan 14 dengan menggunakan glukometer. Dosis nheksana yang digunakan sebesar 0,83 mg/20 gram BB mencit, etil asetat 1,6 mg/20 gram BB, dan etanol 70% 2,9 mg/20 gram BB pemberian dilakukan secara oral setiap hari sampai hari ke 14. Hasil yang diperoleh menunjukan dengan variasi pelarut, daun pohpohan dapat menurunkan kadar glukosa darah puasa terbaik pada ekstrak etanol 70% sebesar 61,10 %
PENGGUNAAN LIMBAH TAHU SEBAGAI NUTRISI SUBSITUSI PADA MEDIA PERTUMBUHAN Staphylococcus aureus
Authors: Yuliana Anna , Adlina Salsabila , Rahmawati Lina
Published: March 2024

Limbah tahu diketahui masih mengandung nutrisi yang dapat dimanfaatkan salah satunya sebagai sumber media pertumbuhan mikroba. Telah dilakukan penelitian mengenai Penggunaan Limbah tahu sebagai nutrisi substitusi pada media pertumbuhan Staphylococcus aureus. Metode yang dilakukan adalah metode plate count dengan beberapa pengujian, yaitu uji kualitatif & kuantitatif protein, uji kualitatif & kuantitatif karbohidrat dan uji penentuan pertumbuhan bakteri. Penentuan kadar protein dan karbohidrat dilakukan dengan menggunakan metode spektrofotometri UV-Vis. Dari hasil penelitian diperoleh bahwa limbah tahu (padat & cair) mengandung protein dengan kadar 278 ppm pada limbah padat dan pada limbah cair sebesar 250 ppm, selain itu limbah tahu juga mengandung karbohidrat yaitu pada limbah padat sebesar 3861 ppm dan pada limbah cair sebesar 2761 ppm. Untuk uji penentuan pertumbuhan bakteri, limbah yang digunakan dibuat dalam beberapa konsentrasi yaitu 20,50 dan 80%. Dari hasil penelitian didapat bahwa limbah padat 50% mempunyai potensi yang lebih baik untuk dijadikan nutrien pada pertumbuhan Staphylococcus aureus.
Pemanfaatan daun kelor (Moringa Leifra) dalam fortifikasi pembuatan nugget
Authors: Matondang Syaiful Nasri , Asmaq Nur
Published: April 2024

Penelitian ini bertujuan untuk mengetahui kualitas nugget daging ayam dengan penambahan tepung daun kelor (Moringa oleifera) pada proses pembuatannya. Bahan yang digunakan dalam penelitian ini adalah daging ayam broiler, tepung daun kelor, tepung terigu, tepung roti, tepung tapioka, telur, air, bawang merah, bawang putih, merica dan garam. Metodologi yang diterapkan ialah eksperimental dengan rancangan acak lengkap non faktorial 4 perlakuan serta 4 ulangan. Parameter yang diuji ialah kadar Antioksidan, kadar Kolestrol, dan Total Koloni bakteri. Perlakuan pada penelitian ini adalah P0 (kontrol / tanpa penambahan tepung daun kelor); P1 (penambahan 5% tepung daun kelor); P2 (penambahan 10% tepung daun kelor), P3 (penambahan 15% tepung daun kelor). Hasil pada penelitian ini memperlihatkan penambahan tepung daun kelor pada pembuatan nugget ayam memberi dampak sangat nyata (P<0,01) terhadap paramater yang di uji.
STUDI IN SILICO SENYAWA HIBRID GABUNGAN PIRAZINAMIDA DENGAN ASAM 4-(2-AMINOTIAZOL-4-IL)BENZOAT
Authors: Zulqurnain Muhammmad , Nurjanah Ana , Wati First Ambar
Published: April 2024

Saat ini, kasus TB terus menjadi tantangan global dengan lebih dari 10 juta kasus baru setiap tahun, dan lebih dari 500.000 di antaranya resisten terhadap obat TB. Indonesia menyumbang sekitar 10% dari total kasus TB global dan menempati peringkat kedua sebagai negara dengan jumlah kasus TB tertinggi di dunia. Peningkatan kasus TB kambuh dipicu oleh resistensi terhadap obat TB sehingga memerlukan pengembangan obat baru yang efektif, singkat dalam pengobatan, dan tidak rentan terhadap Mycobacterium tuberculosis. Pirazinamida merupakan salah satu obat komersial untuk menangani tuberkulosis. Cincin pirazin memiliki peran penting dalam aktivitas bakterisidal. Senyawa yang mengalami N-substitusi dengan 4-feniltiazol-2-amin dan perpanjangan fenil dengan subtitusi gugus asam karboksilat telah terbukti memiliki aktivitas yang efektif. Dalam penelitian ini, dilakukan analisis in silico terhadap senyawa hibrid yang mengombinasikan pirazinamida dengan Asam 4-(2-aminotiazol-4-il)benzoat. Studi in silico melibatkan penelitian studi penambatan, sifat fisikokimia, dan sifat farmakokinetik. Hasil analisis menunjukkan bahwa senyawa hibrid (5) dan (6) memiliki potensi sebagai penghambat protein InhA dan dapat dianggap sebagai kandidat obat oral.
REDUKSI Cr(VI) MENJADI Cr(III) DALAM PERAIRAN MEMANFAATKAN ASAM OKSALAT DARI LIMBAH TONGKOL JAGUNG (ZEA MAYS L) SECARA FOTOKATALITIK
Authors: Nurjanah Ana , Sukmarini Mita Akbar , Husriadi Muh.
Published: April 2024

Bahan pencemar yang sering menjadi perhatian adalah ion-ion logam berat, seperti kromium Cr(VI). efek samping kromium terhadap kesehatan jika terjadi kontak langsung dengan kulit (iritasi), jika terhirup akan menyebabkan iritasi pada gastro-intestinal atau saluran pernapasan, ditandai dengan rasa terbakar, bersin, batuk. Kromium ada di perairan alami diubah dalam dua keadaan yaitu, Cr(VI) dan Cr(III). Cr(VI) mudah larut dalam air dan membentuk divalent oxyanion yaitu kromat (CrO42-) dan dikromat (Cr2O72-) yang dapat menyebabkan penyakit ginjal dan kanker paru-paru. Spesies ion Cr(III) merupakan suatu spesies yang ada dalam makanan yang digunakan untuk untuk mengontrol metabolisme glukosa dan lipid dalam membran sel. Dalam penelitian ini dilakukan uji efektivitas katalis Fe(III) dengan penambahan asam oksalat (reduktor) dalam proses fotoreduksi Cr(VI) menjadi Cr(III). Dimana asam oksalat dari ekstrak tongkol jagung dan reaktor  dengan tengangan lampu UV 30 Watt dengan variasi waktu 10; 20; 30; 40; 50; 60; 120; 180; 240 menit dan katalis 0; 3,8; 7,4; 10,7; 13,7; 16,8 mg/L diukur menggunakan Uv-Vis pada panjang gelombang 540 nm. Maka penelitian ini menghasilkan, asam oksalat dari tongkol jagung yang diuji dengan FTIR gugus O-H, gugus C=O dan gugus C – O. Uji titik leleh asam oksalat yaitu T= 106 – 107 0C. Kondisi setimbang untuk mereduksi Cr(VI) yaitu pada waktu kontak optimum 120 menit. Penggunaan katalis dapat mereduksi ion logam Cr(VI dengan konsentrasi katalis 13,7 mg/L Cr(VI) yang tereduksi sebanyak 71,94%.
Perfil epidemiológico das internações por Doença de Parkinson no Brasil entre 2019 e 2023
Authors: Rysia Gomes Bezerra Thayanne , Sousa Alves Barbosa José Espedito , Ferreira Rodrigues da Cunha Fabiana , Mendonça Raphael Braz João Pedro , Araújo da Silva Carlos , Rocha Pinon Teixeira de Araújo Gabriel , Ferreira de Miranda Izabel , Alves Faria Elter , Leal Soares Felipe , França Lira Leopoldino Clarice , Jorge dias da luz Uelinton , Silva Andrade Letícia
Published: April 2024

Este artigo tem por objetivo analisar as internações por Doença de Parkinson, no Brasil e suas regiões, nos últimos 5 anos. Trata-se de um estudo epidemiológico, acerca das internações decorrentes de Doença de Parkinson, elaborado através de dados secundários, no período de 2019 a 2023, no Brasil e suas macrorregiões. No período analisado, foram registradas 4.399 internações por Doença de Parkinson, no Brasil. Com isso, é possível apontar as internações por Doença de Parkinson na população masculina como um problema de saúde pública que merece a atenção do governo e da sociedade brasileira em geral.
O uso da tomografia computadorizada de feixe cônico como um método eficaz para avaliação de fraturas radiculares: Uma revisão da literatura
Authors: Marcelino William Max do Nascimento , Dias Victor André Tenório , Macêdo Renan de Aguiar Maia , Júnior Miquéias Alves dos Santos , Assis Bianca Maria de Souza , Santos Jair da Silva , Lima Maria Luiza Adriano de Souza , Anjos Rivaldo Marçal dos , Ferreira Diego Rafael Gonçalves , Coutinho Izabela de Freitas , Nascimento João Vitor de Souza , Santos Débora Bezerra dos , Santana Renato Henrique Batista de
Published: April 2024

A ocorrência de fraturas dentárias é caracterizada pela ruptura do tecido dentário, resultando em uma linha visível de descontinuidade que pode se manifestar em diversas orientações. O objetivo deste estudo é buscar responder, por meio da literatura, se a  tomografia computadorizada de feixe cônico (TCFC) pode ser utilizada para o diagnóstico de fraturas radiculares (FR). Para responder a esta questão, foi realizada uma extensa revisão da literatura utilizando bases de dados eletrônicos. Os termos de pesquisa incluíram “tomografia computadorizada de feixe cônico”, “endodontia”, “fratura radicular” e seus equivalentes em inglês correspondente. Foram selecionados apenas artigos relevantes ao tema e publicados entre 2015 e 2024. Os resultados indicam que o TCFC é a técnica de imagem mais eficaz para detectar FR, com um tamanho ideal, produzindo resultados ideais. Porém, é fundamental que o Cirurgião-Dentista (CD) adquira conhecimento sobre o processo do exame para interpretar com precisão os resultados e determinar quando é necessário solicitar uma tomografia computadorizada.
Demência com corpos de lewy: considerações fisiopatológicas e terapêuticas
Authors: Vytor Cardoso Nobre Paulo , De Albuquerque Cavalcante Barreto Rodrigo , Lorenzzo Wanderley de Jesus Correia Victor , Lustosa de Oliveira Avelino Lopes Tulio , Brandão de Albuquerque Maranhão Ernesto , Martins de Brito Igor , Cerqueira de Barros Silveira Vinicius , Del Vecchio Silva Suyane , Cavalcante Rosãngela Natalia Gomes Quintino de Holanda , Souza Marques Victória , Petrius Souza Marques Thomas , Ribeiro Juliana Silva
Published: April 2024

Introdução: A demência com corpos de Lewy (DCL) é uma condição neurodegenerativa caracterizada pela presença de corpos de Lewy, agregados intracelulares compostos principalmente de alfa-sinucleína. Clinicamente, a DCL se manifesta por sintomas cognitivos, como flutuações cognitivas, comprometimento da atenção e da memória, além de sintomas neuropsiquiátricos e sintomas parkinsonianos, como rigidez muscular e tremores. Objetivo: Avaliar a fisiopatologia, a patogênese e o manejo da demência com corpos de Lewy. Metodologia: Trata-se de uma revisão bibliográfica que incluiu artigos originais e revisões sistemáticas em inglês e português, que abordaram as implicações patogências, fisiopatológicas e tratamento da DCL, publicados entre 2012 e 2024, selecionados nas bases de dados PubMed, Scopus e SciELO. Após a seleção criteriosa, foram escolhidos 15 artigos para compor esta revisão bibliográfica. Resultados: A DCL é apresenta aspectos genéticos, incluindo os genes SNCA, GBA e APOE, desempenham um papel importante nesse processo. Além disso, há implicações imunológicas significativas na DCL, com aumento de células T CD3+ e CD4+ em algumas regiões do encéfalo. O tratamento da DCL é desafiador, focando na gestão dos sintomas, com destaque para inibidores da colinesterase para sintomas cognitivos e neuropsiquiátricos. Considerações: A DCL é caracterizada por uma fisiopatologia complexa, marcada por aspectos genéticos e componentes imunopatogênicos relevantes no curso da doença. O manejo clínico da DCL visa principalmente controlar os sintomas, especialmente os cognitivos, neuropsiquiátricos e relacionados ao sono. Tais intervenções terapêuticas são cruciais para melhorar o conforto e a qualidade de vida dos pacientes.
Fissuras labiopalatinas: Revisão de Literatura
Authors: Moreira Gonzalez Silva João Pedro , Tamillles Campos Martins Kassia , Souza da Silva Gabrielle , Caires Sousa da Silva Luciellen , Ferreira Rodrigues da Cunha Fabiana , Mendonça Raphael Braz João Pedro , Eduardo Araújo da Silva Carlos , Lolato Tainara , Alves Rampazzo Juliana , Alvarez Teles de Souza Natália , Faria dos Santos Lamounier Arthur , Lacerda Cardoso Letícia
Published: April 2024

Este artigo tem por objetivo revisar sobre as fissuras labiopalatinas. Trata-se de uma revisão integrativa utilizando como base de dados a BVS, a SciELO, o LILACS e o PubMed, nos últimos 5 anos. Foram avaliados 252 artigos sobre o tema com ênfase em uma síntese dos conhecimentos mais recentes e de maior consistência científica. Conclui-se que as fissuras labiopalatinas podem desencadear uma série de alterações que podem comprometer a fala, nutrição, audição, estética, alterações dentais e psicológicas dentre outras.
TRATAMIENTO DE LA ANSIEDAD Y DEPRESIÓN EN PEDIATRÍA: REVISIÓN DE AVANCES RECIENTES.
Authors: Roballino Zully Stefania Cedeño , Alban Miguel Anderson Tayupanta , Polo Jazmin Natalie Gallegos , Almeida Josselin Fabiola Chávez , Ponce Arianna Lissette Muñoz , Frias Paula Katherine Soria , Ramón Dayanna Briggitte  Obando , Jiménez Paola Anabel Hurtado , Jarrín Karen Johana Salinas , Cruz Fiorella Iveth Castillo , Romero Santiago Paul Lopez
Published: April 2024

La ansiedad y la depresión en niños y adolescentes son desafíos importantes en la salud mental infantil que requieren atención especializada. Es crucial investigar y revisar su tratamiento debido a su impacto en el bienestar emocional, cognitivo y social, así como en su desarrollo a largo plazo. Objetivo: Analizar los avances recientes en el tratamiento de la ansiedad y la depresión en niños, identificando tendencias emergentes y proponiendo recomendaciones para mejorar la atención. Metodología: Las búsquedas se llevaron a cabo en bases de datos electrónicas como PubMed, Scopus y Web of Science, empleando términos de búsqueda específicos relacionados con el temacomo “ansiedad”, “depresión”, “pediatría”, “tratamiento”, “avances recientes”, limitando la búsqueda a estudios publicados desde el 2018 para garantizar la inclusión de la literatura más actualizada. Resultados: Los Inhibidores Selectivos de la Recaptación de Serotonina (ISRS) son el tratamiento principal recomendado para la depresión mayor en niños, con medicamentos como la fluoxetina y la sertralina siendo efectivos. Para la ansiedad, se consideran más efectiva la duloxetina. Las benzodiazepinas no han demostrado superioridad sobre el placebo en el alivio de los síntomas del TAG y presentan efectos adversos significativos. En cuanto a las terapias psicoterapéuticas, se destaca la efectividad de la terapia cognitivo-conductual (TCC) y el potencial beneficio de las terapias basadas en la atención plena y la terapia de juego. La colaboración entre diferentes profesionales de la salud es crucial en el tratamiento integral de estos trastornos.Conclusiones: Se enfatiza la necesidad de investigar y revisar el tratamiento de estos trastornos debido a su impacto en el bienestar emocional, cognitivo y social, así como en su desarrollo a largo plazo. La detección temprana, la intervención adecuada y el seguimiento continuo son fundamentales para mitigar los efectos negativos en la vida de los jóvenes y promover su salud mental futura.
INTELLIGENTIZATION OF DECISION MAKING IN THE SYSTEM MANAGEMENT OF THE TECHNOLOGICAL PROCESS OF ASPHALT CONCRETE MIXTURE PRODUCTION
Authors: Волков И.Н. , Бурковский В.Л. , Шелякин В.П.
Published: April 2024

автомобильные дороги – это важнейшая часть экономической составляющей страны. При этом их надежность и долговечность определяется качеством дорожного покрытия на основе асфальтобетонных смесей. Снижение затрат на производство асфальтобетонных смесей требует развития средств автоматизации, в том числе на базе интеллектуализации соответствующих процессов управления. При производстве асфальтобетонной смеси все процессы связаны между собой. Большое количество нерегулируемых источников внешних и внутренних возмущений в процессе управления данным технологическим процессом, высокая динамика изменения параметров управления существенно усложняют формализацию производства а/б смеси. В статье описаны основные производственные этапы технологического процесса, а также осуществлена их алгоритмизация. Кроме того, выделен основной этап, связанный с поддержанием температуры смеси при смешивании материалов с помощью газовой горелки, который описан в терминах нечеткой логики. Определена зависимость при определенном объеме подачи газа в м3 и температуры, в результате сформированы функции принадлежности, а также матрицы переходов для разных вариантов управления. Данный материал может быть полезен разработчикам средств интеллектуализации управления технологическими процессами с неопределенными параметрами

highways are an important part of the country's industrial infrastructure. Moreover, their reliability and durability are determined by the quality of the road surface based on asphalt concrete mixtures. Reducing the costs of producing asphalt concrete mixtures requires the development of automation tools, including those based on the intellectualization of relevant control processes. The technology for the production of asphalt concrete mixtures includes the following stages: preparatory, main and final, within each of which processes are carried out that are interconnected. A large number of uncontrolled sources of external and internal disturbances in the process of controlling the technological process for the production of asphalt concrete mixtures, the high dynamics of changes in control parameters, significantly complicate their formalization. The article describes the main production stages of the technological process, as well as their algorithmization. In addition, the main stage associated with maintaining the temperature of the mixture when mixing materials using a gas burner, which is described in terms of fuzzy logic, is highlighted. The dependence was determined for a certain volume of gas supply per m3 and temperature, as a result, membership functions were formed, as well as transition matrices for different control options. This material may be useful to developers of tools for intellectualizing the control of technological processes with uncertain parameters
RC OSCILLATOR FOR A DOMESTIC TECHNOLOGICAL PROCESS
Authors: Белявцев А.В. , Русанов А.В. , Шайкина Т.С.
Published: April 2024

предложен сложно-функциональный (СФ/IP) блок RC-генератора, построенный на МОП-транзисторах. Генератор является блоком тактирования для большого числа электронных устройств, не требовательных к стабильности частоты, но чувствительных к размеру. Данный блок предназначен для применения в составе интегральных схем стабилизаторов напряжения. Приведено описание электрической схемы генератора, его основные электрические характеристики и результаты моделирования (зависимости частоты генератора и его тока потребления от температуры и напряжения питания схемы, получены значения нестабильности частоты и зависимость частоты генератора от технологических отклонений, температуры и напряжения питания). Сделан вывод об относительной стабильности характеристик генератора при изменениях внешних параметров и технологических флуктуаций. Приведена топология разработанного СФ блока RC-генератора. Генератор разработан на базе отечественного технологического процесса с проектными нормами 180 нм. Разработка схемы и топологии проводилась в специализированной системе автоматизированного проектирования работ (САПР) интегральных схем. Для моделирования схемы использовались математические модели полупроводниковых приборов, предоставленные фабрикой изготовителем. Топология генератора прошла успешную верификацию на соблюдение проектных норм (Design rule check, DRC) и соответствия топологии исходной схеме (Layout vs. Schematic, LVS)

a functional block (IP) of RC oscillator is proposed. The oscillator is a clocking unit for a large number of electronic devices where frequency stability is not required, but small die size is important. This block is intended for use as part of integrated circuits of voltage regulators. The description of the electrical circuit of the oscillator with electrical specs as well as simulation results are presented. We obtained the following characteristics: oscillator frequency and current consumption plot versus temperature and supply voltage, frequency instability due to process, temperature and voltage variations. Then we have considered the relative stability of the oscillator characteristics under changes in external conditions and technological fluctuations. We present the RC oscillator IP block layout. The oscillator is designed in Russian 180 nm CMOS process. The circuit and layout design were carried out in a specialized IC design CAD system. The mathematical models of semiconductor devices provided by the manufacturer were used to simulate our circuit. The oscillator layout has been successfully verified for compliance with design rules (Design rule check, DRC) and comparing the layout with the schematic (Layout vs. Schematic, LVS)
ПРАВОВАЯ ОЦЕНКА ПРИСВОЕНИЯ НАЙДЕННОГО ИЛИ СЛУЧАЙНО ОКАЗАВШЕГОСЯ У ЛИЦА ИМУЩЕСТВА
Authors: Сафонов В.Н. , Гельдибаев М.Х. , Мальцагов И.Д.
Published: April 2024

В статье рассматривается ставшая в последние годы острой проблема квалификации присвоения найденного или случайно оказавшегося у лица имущества. Отмечаются разнонаправленные подходы в теории уголовного права и в судебной практике к правовой оценке таких действий (чаще всего они квалифицируются как кража или отсутствие состава преступления). Полярность мнений объясняется неочевидностью присущего хищениям признака – изъятия чужого имущества. Правовая неопределенность, считают авторы, привела к нередким нарушениям принципов уголовного права и к обвинительному уклону. Утверждается, что постановление Кон-ституционного Суда России от 12.01.2023 N 2-П расширительно толкует понятие изъятия чужого имуще-ства, что усилит и без того заметный обвинительный уклон. Подход к ответственности за присвоение найден-ного или случайно оказавшегося у лица имущества авторами предлагается решать в зависимости от очевид-ности причины выбывания из фактического обладания собственника имущества (потеря, оставление, забыва-ние). Делается вывод о необходимости включения в УК РФ нормы об ответственности за присвоение найденного или случайно оказавшегося у виновного чужого имущества, заведомо принадлежащего другому собственнику.
Analysis of the sensitization spectrum in patients with severe allergic diseases using the ImmunoCAP ISAC method
Authors: Fomina Daria S. , Lebedkina Marina S. , Nikitina Ekaterina A. , Dushkin Alexander D. , Chernov Anton A. , Yukhnovskaya Yulia D. , Lysenko Mariana A. , Karaulov Alexander V.
Published: April 2024

BACKGROUND: An important advance in modern allergology has been made by the introduction of allergenic molecules/components, including their detection by the ImmunoCAP ISAC method. This method is useful in patients with a complex spectrum of sensitization and severe forms of allergic diseases, where various predictors of severe course are actively searched for.
AIM: To evaluate the informativeness of component resolved diagnostic by ISAC ImmunoCAP method in patients with severe bronchial asthma and severe atopic dermatitis.
MATERIALS AND METHODS: A single-center retrospective study was conducted from January to August 2023. 100 patients who were candidates for biologicals for severe bronchial asthma (group 1; 63 patients), severe atopic dermatitis (group 2; 20 patients), or their combination (group 3; 17 patients) were included. Component restlved diagnostic was performed by ImmunoCAP ISAC method.
RESULTS: Polysensitization and high occurrence of food and fungal allergens were more frequently detected in the groups of patients with severe atopic dermatitis. When analyzing the pollen sensitization spectrum in groups 2 and 3, Bet v 1 and PR-10 family cross-linked molecules (Mal d 1, Pru p 1, Ara h 8, Gly m 4, Cor a 1.04), as well as Ole e 9, Cyn d 1, Ph p 1 and Par j 2 were the most common. Epidermal allergens were common in all three groups. Lipocains (Can f 1, Can f 4, Can f 6, Ecu q 1, Mus m 1), kallikreins (Can f 5), and albumin (Fel d 2) dominated among them. The presence of sensitization to household allergens was detected only in group 2 and only to the molecule Der p 23. Among fungal allergens, the allergen Asp f 6 was predominant in the groups with severe atopic dermatitis, and the component Alt a 1 in patients with severe bronchial asthma. Among food allergens, one of the most common allergens was the molecule Gad c 1, Gal d 1, Gal d 2, Gal d 5 and Bos d 6.
CONCLUSION: Component resolved diagnostic is an accurate assay suitable for determining the spectrum of sensitization in patients; its result can serve as a distinct biomarker for severe allergic diseases.
ELECTRONIC VOTING USING DECENTRALIZED SYSTEM BASED ON ETHEREUM BLOCKCHAIN
Authors: D.Jyothi Reddy  , B. Vineetha Lakshmi  , G.Smily Srinidhi  , B.Udayasri  , Md.Shakeel Ahmed
Published: April 2024

Electronic Voting Using Decentralised System Based On Ethereums Blockchain is a system made in the form of application used for Electronic Voting. This is done to solve the current problem on conventional electronic voting system where the integrity of the data can not be as certain and the result of the vote can be tampered malicious actors. To solve this problem, an electronic voting system will be built that store the data of election results on blockchain to ensure the integrity of the data. The creation of the system involves using the Solidity language, a Turing Complete programming language used on Ethereum. Source code that will be run will rst need to be compiled into Bytecode, which will then in turn run on Ethereum Virtual Machine. The finished program will then be decentralised using Blockchain.
KEYWORDS – Blockchain, Decentralised System, Electronic Voting, Ethereum, Smart Government
PANORAMIC REVIEW OF MANAGEMENT, CONSERVATIVE TREATMENT AND SHOULDER REDUCTION TECHNIQUES
Authors: Bryam Esteban Coello García  , Jessica Alexandra Parra Mejía  , Carolina del Carmen Vélez Andrade  , Geovanna Karolina Cazorla Andrade  , Juan Ignacio Cobos Calle  , Lucy Paulette Zumba Ríos  , Darwin Ismael Cajas Peláez  , Veronica Yajaira Valencia Cañar
Published: April 2024

Introduction: The glenohumeral joint combines a wide range of motion and insufficient bony stabilization, making it susceptible to instability and dislocations. Glenohumeral dislocations are commonly attributed to contact sports, as well as bicycle accidents, falls and high impact trauma.
Objective: to detail current information related to the incidence, clinical evaluation, imaging assessment, management, conservative treatment and shoulder reduction techniques of shoulder dislocations.
Methodology: a total of 30 articles were analyzed in this review, including review and original articles, as well as clinical cases, of which 16 bibliographies were used because the other articles were not relevant for this study. The sources of information were PubMed, Google Scholar and Cochrane; the terms used to search for information in Spanish, Portuguese and English were: shoulder dislocation, glenohumeral dislocation, shoulder reduction maneuvers, shoulder reduction techniques.
Results: The shoulder joint is frequently correlated to dislocations, showing up to 45% of all dislocations. Inferior as well as superior dislocations are rare. Chronic glenohumeral dislocations are infrequent injuries accounting for less than 2%. Anterior glenohumeral dislocations account for about 90% of shoulder dislocations. Approximately 50% to 79% of posterior glenohumeral dislocations are overlooked.
Conclusions: As the epidemiology indicates, there is a high incidence of shoulder dislocations, so it is important to recognize the importance of adequate clinical assessment, diagnosis and knowledge of reduction maneuvers for the management of glenohumeral dislocations. There are several types of maneuvers that can be used for reduction of a dislocated shoulder, these maneuvers can be chosen according to the case of the affected individual, in addition to the preference and experience of the person who is going to perform the reduction maneuver. Imaging tests play an important role both at diagnosis and post-reduction to confirm reduction.
KEY WORDS: shoulder, dislocation, techniques, reduction, conservative.
Dampak Capital Adequacy Ratio, Biaya Operasional Pendapatan Operasional Dan Non Performing Financing Terhadap Return On Asset Bank Umum Syariah Tahun 2016-2019
Authors: Surono Surono , Djadjuli Mohammad , Margapradja Harry Safari , Tatmimah Itat , Muzayyanah Muzayyanah
Published: April 2024

Dampak faktor-faktor tertentu terhadap kinerja keuangan bank syariah di Indonesia secara lebih mendalam. Penelitian ini bertujuan untuk menginvestigasi kinerja bank dalam aspek profitabilitas, efisiensi, dan tingkat risiko di Bank Syariah di Indonesia dari tahun 2016 hingga 2019 atas masalah . Data time series dikumpulkan dari Laporan Keuangan Publikasi Tahunan Bank Syariah dan dipilih melalui tahap purposive sampling. Sampel penelitian terdiri dari 9 Bank Syariah di Indonesia selama periode 2016-2019. Metode yang diterapkan kuatitatif dengan uji validitas, realibilitas dan asumsi klasik, sedangkan analisis data menggunakan analisis regresi berganda. Hasil analisis data menunjukkan bahwa Capital Adequacy Ratio (CAR) memiliki pengaruh positif terhadap Return On Asset (ROA), sementara Biaya Operasional terhadap Pendapatan Operasional (BOPO) dan Non Performing Financing (NPF) memiliki pengaruh negatif terhadap ROA pada Bank Umum Syariah di Indonesia periode 2016-2019. Temuan ini memberikan kontribusi penting dalam pemahaman tentang faktor-faktor yang memengaruhi kinerja keuangan bank syariah dan memberikan arahan bagi praktisi dalam pengambilan keputusan keuangan
Розробка автоматизованої системи ідентифікації підпису особи
Authors: Kovivchak Ya. , Dubuk V. , Buchkovsky M.
Published: March 2024

У стат­ті приведено розробку автоматизованої системи ідентифікації підпису особи. Обґрунтовано актуальність розробки. Здій­сне­но аналіз існуючих подібних систем, розглянуто їх переваги та недоліки. Побудовано концептуальну модель сис­теми іден­ти­фікації підпису особи. Побудовано діаграму використання для користувачів системи. Розроблено блок-схему ал­го­рит­му ро­боти системи. Приведено функціональну модель системи. Розроблено діаграму класів автоматизованої сис­те­ми іден­ти­фікації підпису особи. Реалізовано базу даних. Приведено діаграму компонентів системи. Здійснено реа­лі­за­цію ком­по­нентів сис­теми, бази даних та інтерфейсу користувача. Запропонована автоматизована система ідентифікації під­пи­су лю­ди­ни може знай­ти успішне використання у різних областях людської діяльності, а саме, у банківській справі, юри­дич­ній сфе­рі, ме­ди­ци­ні, в діловодстві. Застосування розробленої системи на практиці допоможе забезпечити авто­матизацію про­це­су визначення ав­тентичності підпису особи. Це пришвидшить процеси ідентифікації підписів та змен­шить ризики шах­рай­ст­ва при іден­ти­фі­кації особи, підвищить рівень захисту документів
Розробка підсистеми автоматизованого управління відносинами з клієнтами малого бізнесу
Authors: Melnyk A. , Kynash Yu.
Published: March 2024

У стат­ті приведено розробку підсистеми автоматизації управління відносинами з клієнтами на базі CRM-системи. В статті обґрунтовано актуальність розробки, розглянуто способи автоматизації управління відносинами з клієнтами, проведено аналіз наявних в Україні подібних систем. Приведено діаграму використання підсистеми для користувачів. Розроблено блок-схеми ал­го­рит­мів ро­боти. Приведено діаграму взаємодії модулів системи. Спроектовано базу даних та розроблено діаграму класів системи. Розроблено інтерфейс користувача та реалізовано програмні модулі. Запропонована підсистема автоматизованого управління може успішно використовуватися у сфері діяльності малого бізнесу. Практичне значення розробленої системи полягає у можливості автоматизувати взаємодію підприємства з клієнтами. Підсистема буде використовуватися для збереження даних про клієнта, товари і угоди. Використання підсистеми забезпечить автоматизацію частини рутинної роботи, наприклад, при веденні угод. Завдяки цьому, мінімізується кількість помилок в роботі підприємства і підвищується продуктивність загалом