bluuebunny/crossref_metadata_2025 huggingface dataset:
Comparison of the accuracy of two techniques for three-dimensional digital indirect bonding of orthodontic brackets: A randomized controlled trial
Authors: MAHRAN Ahmed Abdelhalim , REFAI Wael Mubarak , HASHEM Ahmed Shawky
Published: July 2024

ABSTRACT Objective: This study aimed to clinically compare the accuracy of bracket positioning between three-dimensionally (3D) printed indirect bonding trays and vacuum-formed trays made over 3D-printed models. Material and Methods: Fourteen patients, planned for fixed orthodontic therapy, were randomly divided into two equal groups. For both groups, both dental arches were scanned, to acquire virtual models, brackets were virtually positioned from central incisors to second premolars, and scans for the final bracket positions were performed. In the first group, transfer trays were 3D-printed. In the second group, virtual models were 3D-printed, and vacuum-formed soft sheets were thermoformed on the printed model. Teeth were indirectly bonded and then scanned. Superimposition of the virtual and the final bracket positioning scans was performed to measure linear and angular deviations in brackets positions. Results: The first group showed significantly less occlusogingival and buccolingual linear errors than the second group. No significant differences in angular deviations were found between both groups. The frequencies of clinically acceptable linear errors within 0.5 mm and angular errors within 2° showed no statistically significant difference between both groups (p> 0.05 for all measurements). The transfer errors in both groups showed linear directional biases toward the mesial, gingival and labial directions. There was no statistically significant difference in the rate of immediate debonding between both groups (10.7% and 7.1% for the first and the second groups, respectively, p=0.295). Conclusions: 3D-printed indirect bonding trays were more accurate than vacuum-formed trays, in terms of linear deviations. Both types of trays showed similar angular control.
Caracterização da vegetação do Parque Estadual Lagamar de Cananéia, Litoral Sul, Estado de São Paulo, Brasil
Authors: Ivanauskas Natália Macedo , Moura Claudio de , Kameyama Cíntia , Shirasuna Regina Tomoko , Arzolla Frederico Alexandre Roccia Dal Pozzo , Costa Janaina Pinheiro , Kanashiro Marina Mitsue , Martins Tatiana Parreiras , Baitello João Batista , Aguiar Osny Tadeu de , Prado Jefferson , Simão-Bianchini Rosângela , Rossi Lucia , Fernandes Ulisses Gonçalves
Published: July 2024

RESUMO A Mata Atlântica é um “hotspot” de biodiversidade, devido a sua elevada riqueza, endemicidade e ameaças. Caracterizamos as fitofisionomias e listamos as espécies vasculares do Parque Estadual Lagamar de Cananéia (PELC). Foram coletadas as espécies de diferentes hábitos encontradas ao longo das trilhas percorridas no PELC e o mapeamento das fitofisionomias foi feito por fotointerpretação. Mapeamos oito fitofisionomias vegetacionais, com Floresta Ombrófila Densa Submontana, representando 53,9%, enquanto as Montanas e das Terras Baixas cobriram 14,3% e 13,2%, respectivamente. A flora conhecida do PELC é composta por 540 espécies vasculares distribuídas em 122 famílias, sendo 55 espécies de Samambaias e Licófitas, duas Gimnospermas e 483 Angiospermas, com espécies em risco de extinção (20 espécies). O PELC possui fitofisionomias importantes e flora com elevada riqueza de espécies, ratificando sua importância para a conservação da biodiversidade da Mata Atlântica no Estado de São Paulo.
Prescrição de benzodiazepínicos em Unidades Básicas de Saúde em uma comunidade com alta vulnerabilidade social
Authors: Bigal André Luiz , Nappo Solange Aparecida
Published: July 2024

RESUMO Os benzodiazepínicos, medicamentos mais prescritos no mundo, são extremamente úteis no manejo de patologias relativas ao sistema nervoso central, porém, nem sempre sua prescrição está relacionada com uma patologia. Este estudo buscou identificar os fatores influenciadores na prescrição de benzodiazepínicos na Atenção Básica do Sistema Único de Saúde e suas consequências, em uma região com alta vulnerabilidade social. Foram utilizados os princípios de um estudo qualitativo com amostra intencional de médicos prescritores construída com a ajuda dos Informantes-Chave e com tamanho (n = 10) definido pelo princípio da saturação teórica. A coleta de dados ocorreu mediante entrevistas semiestruturadas nas unidades básicas onde os profissionais atuavam. Os temas identificados relativos aos motivos da prescrição foram: relativos ao paciente (demanda do paciente; problemas sociais); relativos ao medicamento (dependência); relativos ao prescritor (uso irracional). A prescrição do benzodiazepínico deu-se devido às baixas condições sociais dos usuários nessa região e as consequências dessa conjuntura (vulnerabilidade social, problemas angustiantes de difícil resolução). Educação permanente para profissionais, ações interprofissionais e integralidade do cuidado foram demandas dos profissionais. O problema extrapola a ação do médico, e são sugeridas políticas públicas que garantam, às populações com essas características, acesso a saúde, trabalho e educação.
Validação transcultural da ImpRes-Tool-BR: uma ferramenta para desenvolvimento de projetos e pesquisas de implementação
Authors: Treichel Carlos Alberto dos Santos , Chavez Leidy Janeth Erazo , Sevdalis Nikolaos , Bakolis Ioannis , Hull Louise Mary , Campos Rosana Teresa Onocko
Published: July 2024

RESUMO Este estudo tem como objetivo apresentar os resultados da tradução, validação transcultural e avaliação preliminar de uma ferramenta, originalmente desenvolvida no Reino Unido, para orientar pesquisadores brasileiros na elaboração de projetos e pesquisas de implementação rigorosos e de alta qualidade: ImpRes-BR. Seguindo boas práticas atualmente estabelecidas para validação transcultural de instrumentos e escalas, a ferramenta, juntamente com seu guia de utilização, foi traduzida e retrotraduzida, submetida a um teste piloto com 20 profissionais de saúde e avaliada por um painel de 10 especialistas que atribuíram os valores utilizados para os cálculos do Índice de Validade de Conteúdo ao nível do item (IVC-I) e escala (IVC-E). Nesse processo, além de índices de validade conceitual superiores à 90%, foi observado um IVC-I de pelo menos 0,90 em todos os domínios da ferramenta e seu guia e um IVC-E de 0,98. Estabelecida a validade da ferramenta e seu guia, a mesma foi aplicada em 14 projetos de pesquisa em fase de planejamento ou execução e foi reconhecida enquanto um instrumento potente para autoanálise das equipes na qualificação de seus projetos e fortalecimento destes em relação aos princípios da Ciência de Implementação.
O trabalho das equipes de saúde bucal na pandemia da covid-19 segundo gestores de saúde
Authors: Fagundes Juliane , Kusterer Liliane Elze Falcão Lins , Moreira Marcela Beatriz Aguiar , Lima Adeilda Ananias de , Kruschewsky Julie Eloy , Menezes Erica Lima Costa de , Carvalho Fernando Martins
Published: July 2024

RESUMO Este estudo objetivou caracterizar o trabalho dos profissionais das equipes de saúde bucal da rede pública na pandemia da covid-19 do ponto de vista dos gestores. Trata-se de um estudo quantitativo-qualitativo, com 163 gestores municipais de saúde da Bahia, que responderam a um questionário virtual, de junho a outubro de 2020. Foi realizada análise descritiva dos dados quantitativos utilizando o Statistical Package for the Social Science, e Análise Temática das respostas subjetivas, com auxílio do IRaMuTeQ. Um escopo de atuação das equipes de saúde bucal, que atuam em todos os níveis de atenção à saúde, foi reconhecido como mais abrangente que o tradicional nesse período. A pandemia deu ênfase às fragilidades crônicas nas condições de trabalho dos cirurgiões-dentistas, técnicos e auxiliares de saúde bucal da rede pública, como a insuficiência de instrumentais odontológicos e de insumos, a precária manutenção dos equipamentos odontológicos, a fragilidade dos vínculos empregatícios e a estrutura física inadequada nas unidades de saúde, comprometendo a biossegurança. Assim, abre-se uma oportunidade para identificar e implementar mudanças necessárias não apenas no contexto de crise sanitária, mas também no período pós-pandemia.
‘Uma parte de mim sabia que isso aconteceria um dia’: vivências de jovens com HIV/aids
Authors: Fonseca Beatriz Sousa da , Rodrigues Thamires Fernandes Cardoso da Silva , Silva Guilherme Malaquias , Pimenta Rosangela Aparecida , Silva Marcelo da , Furtado Marcela Demitto , Merino Maria de Fátima Garcia Lopes
Published: July 2024

RESUMO O objetivo deste estudo foi compreender as representações sociais de jovens que vivem com o HIV. Estudo qualitativo, ancorado na Teoria das Representações Sociais, realizado com 16 jovens em acompanhamento ambulatorial. Os dados foram coletados entre maio e outubro de 2022, por meio de entrevista semiestruturada. Para o tratamento dos dados, empregou-se a técnica de análise lexical, operacionalizada com o auxílio do software Iramuteq. A representação fortemente associada ao diagnóstico de HIV está relacionada ao desconhecimento, preconceito e aceitação, apresentando, também, elementos positivos como recomeço. Classes: Diagnóstico positivo para o HIV: o ‘eu’ de agora; HIV em face do desconhecimento e do estigma; e Relações interpessoais: diálogo, acolhimento e respeito necessários aos jovens. Compreendeu-se que as representações sociais dos jovens com HIV refletem a sua condição na sociedade. Os dados deste estudo mostram que existem formas distintas de vivenciar o HIV, muitas vezes representadas pela fragilidade, pela resignação, e outras, pelo fortalecimento. A fim de minimizar a vulnerabilidade do jovem à exposição ao HIV e aos riscos de conviver com o estigma e preconceito social, fazem-se necessárias a adoção de estratégias de conscientização da sociedade sobre a doença e a ampliação da divulgação de políticas públicas que abarcam essa temática.
Uso de estratégias inovadoras no ensino da Saúde Coletiva nas graduações da área da Saúde: uma revisão de escopo
Authors: Mendes Ramon de Souza , Anunciação Kim Charles Oliveira dos Santos , Fonseca Bárbara Suellen , Silva José Adailton da , Salvador Pétala Tuani Candido de Oliveira
Published: July 2024

A Saúde Coletiva percebe a saúde como resultado de conjunturas sociopolíticas e econômicas. A aplicação de seus conceitos pelos estudantes dessa área pode ampliar a garantia de direitos fundamentais. Assim, o presente artigo objetiva mapear quais são as estratégias de ensino inovadoras que têm sido utilizadas no ensino da Saúde Coletiva em cursos de Graduação da área da Saúde. Trata-se de revisão de escopo realizada em setembro de 2022 em 12 fontes de pesquisa, que totalizou uma amostra de 37 publicações. Em número de publicações, o Brasil se destacou, seguido de países de língua inglesa, bem como os cursos Medicina, Enfermagem e Odontologia. Estratégias que valorizam a construção do conhecimento, a criticidade e a autonomia do aluno foram maioria, refletindo demandas contemporâneas e quebras de paradigmas nas últimas décadas na saúde.
Avaliação da percepção dos professores sobre educação interprofissional em saúde por meio de grupos focais
Authors: Menezes Cláudia Callegaro de , Rangel Alex Silva , Leão Anna Thereza Thomé , Barros Maria Cynésia Medeiros de
Published: July 2024

Este estudo avalia a percepção de docentes de uma universidade pública brasileira sobre educação interprofissional (EIP). Professores de Medicina, Odontologia e Enfermagem participaram de grupos focais on-line síncronos refletindo sobre os seguintes tópicos: (1) disciplinas em comum; (2) projetos interprofissionais de pesquisa e extensão; (3) atenção aos determinantes sociais nos planos de tratamento aos usuários; e (4) práticas colaborativas durante a pandemia de Covid-19. Foi usada análise interpretativa descritiva para avaliar quatro grupos focais (n = 10) utilizando instrumento estruturado com 17 itens acerca dos quatro tópicos mencionados. Segundo os docentes, não existem disciplinas comuns entre os cursos da Saúde. Projetos de extensão e de pesquisa com abordagem interprofissional acontecem somente por poucas iniciativas individuais de professores. Segundo os participantes, os alunos consideram os determinantes sociais nos planos de tratamento. Ocorreram poucas práticas colaborativas durante a pandemia. Observou-se a necessidade de orientações sobre EIP para graduação.
Práticas de articulação de rede na atenção psicossocial: quais desafios enfrentam os profissionais para matriciar, reunir-se e encaminhar?
Authors: Carlos Michelle de Menezes , Gallassi Andrea Donatti
Published: July 2024

Este estudo se propôs a explorar as práticas de articulação de rede desenvolvidas pelos profissionais atuantes em dois pontos da Rede de Atenção Psicossocial do Distrito Federal: os Centros de Atenção Psicossocial Álcool e outras Drogas e as Unidades Básicas de Saúde, abrangendo as sete regiões de saúde existentes, evidenciando as estratégias utilizadas, bem como as dificuldades e os desafios que atravessam sua implementação à luz do modelo de Atenção Psicossocial (AP). Trata-se de uma pesquisa com abordagem qualitativa e enfoque exploratório com 36 participantes entrevistados; utilizou-se a triangulação intramétodo e adotou-se a análise de conteúdo de Bardin. Identificaram-se a falta de infraestrutura e de insumos para tecer as práticas de matriciamento, reuniões com a rede e encaminhamentos de forma satisfatória, conforme a perspectiva dos participantes. Contudo, surgiram estratégias interventivas e de promoção de saúde para o fortalecimento da AP.
Does CLIP Know My Face?
Authors: Hintersdorf Dominik , Struppek Lukas , Brack Manuel , Friedrich Felix , Schramowski Patrick , Kersting Kristian
Published: July 2024

With the rise of deep learning in various applications, privacy concerns around the protection of training data have become a critical area of research. Whereas prior studies have focused on privacy risks in single-modal models, we introduce a novel method to assess privacy for multi-modal models, specifically vision-language models like CLIP. The proposed Identity Inference Attack (IDIA) reveals whether an individual was included in the training data by querying the model with images of the same person. Letting the model choose from a wide variety of possible text labels, the model reveals whether it recognizes the person and, therefore, was used for training. Our large-scale experiments on CLIP demonstrate that individuals used for training can be identified with very high accuracy. We confirm that the model has learned to associate names with depicted individuals, implying the existence of sensitive information that can be extracted by adversaries. Our results highlight the need for stronger privacy protection in large-scale models and suggest that IDIAs can be used to prove the unauthorized use of data for training and to enforce privacy laws.
This article appears in the AI & Society track.
HEAT TRANSFER ENHANCEMENT BEHIND AN OBSTACLE IN A CHANNEL FLOW UNDERGOING TRANSITION TO TURBULENCE
Authors: Mazo Aleksandr Bentsianovich , Kalinin Evgueniy Igorevich , Molochnikov Valery , Okhotnikov Dmitry , Paereliy Anton A. , Dushina Olga A.
Published: July 2024

Direct numerical simulation of heat transfer behind a spanwise obstacle was carried out in a steady channel flow.
Reynolds numbers corresponded to transition to turbulence in the separation region behind the obstacle. The obstacle
was mounted either on the channel wall or with a gap from the wall. Thorough verification of numerical results (visual
flow pattern and flow statistics) against experimental data was carried out. Distributions of local coefficients of heat
transfer and skin friction behind the obstacle were found to correlate with the vortical structure of the flow. For both
positions of the obstacle relative to the channel wall, the study discovered principal regularities in the behavior of local and averaged, across the channel, values of heat transfer behind the obstacle with the varying Reynolds number of the oncoming flow. The effect of obstacle position on the total increase in the heat transfer coefficient on the wall behind the obstacle was estimated in comparison with the smooth wall.
The Gamergate Social Network: Interpreting Transphobia and Alt-Right Hate Online
Authors: Bevan Catherine Ilona , Tunggal Jesaya Samuel , Zhang Andy , Rockwell Geoffrey
Published: July 2024

This paper explores the relationship of transphobia and other forms of harassment found across the events of the Gamergate hate movement through the development of an interactive social network analysis. With the social network being derived from hundreds of events tagged by hand, special consideration is given to the positionality and biases of its authors and how they affected this specific interpretation of Gamergate events. Informed largely by the transgender perspective of its first author, this paper draws particular conclusions around the propagation of transphobia in online hate movements, such as its intersectionality with other ideological cornerstones of Gamergate.
Cet article explore la relation entre la transphobie et d’autres formes de harcèlement observées lors des événements du mouvement de haine Gamergate à travers le développement d’une analyse de réseau social interactive. Avec le réseau social dérivé de centaines d’événements étiquetés à la main, une attention particulière est accordée à la position et aux biais de ses auteurs et à la manière dont ils ont influencé cette interprétation spécifique des événements de Gamergate. Principalement informé par la perspective transgenre de son premier auteur, cet article tire des conclusions particulières sur la propagation de la transphobie dans les mouvements de haine en ligne, comme son intersectionnalité avec d’autres piliers idéologiques de Gamergate.
History of the CT scan
Authors: Spielman Andrew I. , Forrai Judit
Published: July 2024

A CT (Computer Tomography) X-ray is a combination of radiographs taken from multiple angles along a circular trajectory and recombination of the image with the aid of computers into slices of images. An entire organ or body can be "sliced" this way, visualizing pathologies that would otherwise be non-observable through regular X-rays.
Gastronomi Hikayeleri
Authors: Özdemir Esranur
Published: July 2024

‘Çocuklara Gastronomi Dünyasını Keşfettiren Bir Başyapıt: Gastronomi Hikayeleri’
Esranur Özdemir’in ‘Gastronomi Hikayeleri’ adlı kitabı, gastronomi alanında çığır açan bir eserdir. Kitap, çocuklara yemek kültürü, sağlıklı beslenme, sürdürülebilirlik konularında eğlendirici yaklaşımının yanında öğretici bir yaklaşımla bu konulara değinir. Her hikaye, mutfak dünyasını keşfetmelerini sağlamaktadır. Ayrıca kitap, sürdürülebilirlik ve gelecek için sorumluluk alma konularında da bilinç kazandırmaktadır.
Postcolonial and Postsocialist Positions: Contestational Poetry in the Global Capitalist World
Authors: Gržinić Marina
Published: July 2024

The paper suggests considering alliances and coalitions from two perspectives: postsocialism and postcolonialism. This is because both terms, while referring to different geopolitical realities, share the prefix “post” and highlight the importance of questioning relationships between different subjectivities. The author argues that it is crucial to examine the intersection of these two lines and address the issues of racial and gender divisions, ra-cialisation, and class antagonisms within the dominant structures of West European na-tion-states. Without doing so, it would be impossible to think of effective alliances and coa-litions in Europe or contemporary revolutionary poetry. The article proposes a materialist analysis of global capitalism and advocates a different type of knowledge and politics that is transfeminist, migrant, politically subversive, and sexually transgressive. The author also suggests three starting points to propose politically constructed genealogies and entangle-ments for revolutionary narratives in and of the world. In doing so the lines we obtain are: decolonisation and #BlackLivesMatter!, the LGBTQI+ poetess in the former Yugoslavia, and new, post-, and transfeminism(s) of Colour, Black feminisms, and Chicana. Overall, the author insists on the importance of understanding the complexities and intersections of different subjectivities and geopolitical realities in order to build effective alliances and pro-mote revolutionary narratives.
Вопросы распоряжения налогоплательщиком положительным сальдо единого налогового счета
Authors: Mardasova М. Е.
Published: July 2024

Изучаются особенности распоряжения налогоплательщиком положительным сальдо его единого налогового счета. Рассматриваются варианты реализации указанного права путем зачета и возврата денежных средств с учетом внесенных в Налоговый кодекс РФ изменений, которые обусловлены установлением унифицированного порядка уплаты налогов и других налоговых платежей. Отдельное внимание уделяется законодательным ограничениям осуществления налогоплательщиком права распоряжения положительным сальдо единого налогового счета.
О применении общего запрета на недобросовестную конкуренцию при неисполнении или ненадлежащем исполнении публично-правовых обязанностей
Authors: Oleinik P.V.
Published: July 2024

Обобщается практика антимонопольного органа при квалификации непоименованных форм недобросовестной конкуренции. Анализируется повсеместное применение института пресечения недобросовестной конкуренции при нарушении субъектами иного отраслевого законодательства. Аргументируется, что при применении общего запрета на недобросовестную конкуренцию антимонопольный орган не должен подменять иные органы, входящие в единую систему публичной власти в Российской Федерации. Вносятся предложения об изменении правоприменительного подхода антимонопольного органа.
Российская Федерация как государство-правопреемник: конституционно-правовой подход
Authors: Maslennikova S.V.
Published: July 2024

Поправки к Конституции РФ 2020 г. о признании Российской Федерации правопреемником Союза ССР актуализировали необходимость понимания правопреемства государства. В данной статье анализируются различные правовые основания и последствия признания правопреемства государства и народа в отношении имущества и ценностей, перешедших от прежних поколений в связи с историческими трансформациями публично-правовых образований. Приводятся подтверждения того, что правопреемство России может распространяться за пределы статуса государства на международной арене. Доказывается, что народ и государство являются правопреемниками как в отношении собственности, включая национальное достояние как основу жизнедеятельности общества, так и духовно-культурных ценностей, например, памятников истории и произведений искусства. В исследовании использовался формально-юридический метод для анализа решений французских судов о принадлежности Российской Федерации по правопреемству Собора Св. Николая в Ницце и постановления Конституционного Суда РФ об обеспечении государством прав реабилитированных жертв политических репрессий. Историко-правовой анализ позволил прийти к выводу о необходимости обращения к историческим документам, фактам и событиям при установлении субъектов и объектов правопреемства. При доказательстве правопреемства народа и государства используются преимущественно публично-правовое регулирование и публично-правовая аргументация. В статье рассматриваются различные конституционно-правовые позиции, которые позволяют доказать непрерывность бытия народа и государства и связи между субъектами, а также объектами, им принадлежащими. Ключевые слова: правопреемство, Российская Федерация, преемственность традиций, непрерывность, народ, государство, территория, орган, собственность, право собственности, ценность, культура, история, суверенитет.
Профессия медиатора: актуальные вопросы нормативного регулирования в России
Authors: Минкина Наталья
Published: July 2024

Рассматриваются актуальные вопросы нормативного регулирования отечественной профессии медиатора. Обосновывается ее ценность для развития общества, анализируются законодательные требования к профессиональным медиаторам. Делается вывод о небыстрых процессах становления данной профессии в России. Научная новизна работы представлена в комплексном социолого-юридическом исследовании проблематики, основанном на анализе научных мнений, законодательных и иных актов, позиций профессиональных медиаторов, некоторого зарубежного опыта, сопровождающемся авторскими суждениями. Оригинальность работы заключается в обобщении в ней результатов проведенного социологического опроса профессиональных медиаторов по ряду дискуссионных вопросов темы. К ним отнесены: необходимость сохранения непрофессиональной медиации, законодательное установление минимального возраста для профессионального медиатора, требования к его уровню образования и прохождению специального обучения, правовое регулирование онлайн-медиации, перспектива внедрения цифрового медиатора и применения искусственной нейронной сети в проведении процедуры медиации. Результаты настоящего исследования могут стать предметом для научного обсуждения и последующего его изучения учеными, также могут быть положены в основу разработки положений нового закона, которым регулируется процедура медиации и статус медиатора.
Проблемы правового регулирования авторских прав на произведения, созданные нейросетью
Authors: Dragunova S.A.
Published: July 2024

Анализируются существующие подходы к возможности авторско-правовой охраны произведений, созданных нейросетью. В частности, рассмотрен опытотдельных зарубежных стран по признанию результатов, сгенерированных искусственным интеллектом, в качестве объектов авторских прав; исследованы лицензионные соглашения наиболее крупных сервисов ИИ, включая Midjourney, ChatGPT. Отдельное внимание уделено анализу сложившихся подходов к пониманию созданных нейросетью работ как объектов правовой охраны, выявлены достоинства и недостатки каждого из подходов. В заключении затронуты вопросы ответственности при нарушении нейросетью чужих интеллектуальных прав в процессе генерации контента.
Компетенция президента Российской Федерации в сфере организации подготовки научно-педагогических кадров: современное состояние и вопросы реализации
Authors: Rukavishnikov S.M.
Published: July 2024

На текущем этапе развития государства инициатива Президента РФ является катализатором усилий всей системы государственного управления, а также законодательной власти по выработке подходов к формированию новой модели организации высшего образования и подготовки научно-педагогических кадров. Это проявилось во введении экспериментального правового режима, направленного на апробацию новых уровней профессионального образования. Также актуальным является вопрос о реализации метода стимулирования при подготовке научно-педагогических кадров. Формулируются выводы о целесообразности дополнения законодательства об образовании посредством уточнения полномочий Президента РФ в области проведения образовательных экспериментов, а также о необходимости совершенствования правовой политики в сфере стимулирования исследовательской деятельности аспирантов и докторантов.
Genotype-by-environment interaction of Solanum quitoense (Lam.) using the AMMI model
Authors: Lagos-Santander Liz Katherine , Duarte-Alvarado David Esteban , Lagos-Burbano Túlio César
Published: July 2024

The basis for genetic improvement for the cultivation of lulo (Solanum quitoense Lam.) in Colombia is limited. Research related to genotype-by-environment interaction (GEI) and stability in agronomic traits is scarce. To identify outstanding genotypes, GEI and the stability of fruit weight (FW), ascorbic acid (AA), and yield of 10 half-sib families (HSF) were evaluated. At the locations of San Pedro de Cartago, Arboleda, Tangua and La Union of the department of Nariño (Colombia), four trials were established under the randomised complete block design with four repetitions. To analyse GEI, the additive main effects and multiplicative interaction (AMMI) model and some AMMI stability parameters were used. In yield, the HSF7 and the control presented specific adaptation for Tangua, with 12.82 and 13.41 t ha-1, respectively and FW greater than 100 g. In Arboleda, HSF29 obtained the highest yield (16.14 t ha-1) with an FW of 100.53 g. HSF4, HSF28 and HSF49 reached yields above 9.0 t ha-1 and a FW greater than 100 g; therefore, they are recommended for any of the environments evaluated given their stability. HSF25 in AA and HSF29 in yield presented specific adaptation in Arboleda. Stable families across environments and with good yield were HSF4, HSF28, and HSF49, HSF4 and HSF28 showed higher values in two of the three traits, and HSF49 was outstanding in all three variables. These families can be used in plant breeding programmes as parents or distributed to farmers as improved varieties.
Effectiveness of acetic and citric acid against Staphylococcus aureus contamination in parsley and dill
Authors: Usanmaz Asiye , Erdoğan Ahmet , Baran Alper
Published: July 2024

Staphylococcal food intoxication from Staphylococcus aureus (S. aureus) species is an important food-borne disease that threatens public health in many countries. Products prepared with fresh vegetables that have not been heat treated and/or not sufficiently disinfected are particularly risky. In this study, the effects of various organic acid (acetic and citric acid) concentrations on S. aureus previously inoculated into parsley and dill vegetables were investigated at storage time of 0, 1., 3., 5, and 7 days. For this purpose, a total of 7 groups were formed: individually with 0.5% and 1.5% acetic and citric acid, as well as their combinations and control. The number of S. aureus was adjusted to 102 and 106 (log CFU/mL) numbers that known to produce toxins by spectrophotometric method. As a result of the study, acetic and citric acid were found to be more effective when combined in S. aureus inhibition. It was observed that this effect varies depending on the microbiological load, acid concentration and storage days of the vegetables. It was also determined that the organic acids used had a better effect on the parsley than the dill vegetable.
RESERVOIR QUALITY EVALUATION: UNVEILING DIAGENETIC TRANSFORMATIONS THROUGH MINERALOGICAL AND PETROPHYSICAL ANALYSES OF THE UPPER MIOCENE LACUSTRINE SANDSTONES IN THE PANNONIAN BASIN SYSTEM, CROATIA
Authors: Matošević Mario , Tomašić Nenad , Perković Adaleta , Kampić Štefica , Kovačić Marijan , Pavelić Davor
Published: July 2024

The Upper Miocene lacustrine sandstones of the North Croatian Basin, located in the southwestern Pannonian Basin System, represent significant reservoirs for hydrocarbon exploration, yet their diagenetic evolution remains poorly understood. This study offers a comprehensive investigation into the diagenesis of these sandstones, analyzing samples from 14 exploration wells in the Sava and Drava depressions. Using petrographic analyses, scanning electron microscopy with energy-dispersive X-ray spectroscopy (SEM-EDS), X-ray diffraction (XRD), and petrophysical measurements, we aimed to explain the diagenetic processes affecting reservoir quality and hydrocarbon productivity. Our results reveal a consistent grain size distribution, modal composition, and diagenetic alterations across both depressions. Compaction, evidenced by evolving grain contacts and pressure dissolution, leads to a depth-dependent reduction in porosity. Carbonate cements, notably calcite and Fe-dolomite/ankerite, are primary contributors to reduction of primary intergranular porosity, alongside clay minerals, quartz, feldspar, etc. Secondary porosity resulting from dissolution and redistribution processes also significantly influences overall porosity evolution. Clay minerals, detrital and authigenic, exhibit a complex interplay with other diagenetic processes, further reducing porosity and permeability. Authigenic clay minerals, including illite, chlorite, and kaolinite, act as pore-filling cement or coatings, hindering fluid flow. Paragenetic processes delineate the intricate relationship between mineralogical transformations and petrophysical properties, defining reservoir quality. Understanding diagenetic dynamics is essential for predicting reservoir quality, fluid migration pathways, and hydrocarbon productivity. This study fills a crucial knowledge gap regarding the diagenesis of the Upper Miocene lacustrine sandstones in the southwestern part of the Pannonian Basin System, providing insights vital for the energy sector and supporting sustainable resource development in the region.
PREDICTION OF RATE OF PENETRATION (ROP) IN PETROLEUM DRILLING OPERATIONS USING OPTIMIZATION ALGORITHMS
Authors: Ebrahimabadi Arash , Afradi Alireza
Published: July 2024

In drilling operations, by choosing the proper tools and also incorporating more accurate and reliable parameters, this operation can be performed in less time and cost manner. Among drilling parameters, Rate of Penetration (ROP) is viewed as the main parameter in drilling operation evaluation. Field data investigations can be considered the most fruitful approaches to evaluate drilling performance, or ROP, as well as development of predictive models although laboratory tests and experimental formulas are vastly used to identify the drilling problems. In this research, intelligent modeling was used to predict the penetration rate of drilling operations through analyses of an established comprehensive data base from drilling operations in one of Iranian oilfields, Shadegan oilfield, in which novel artificial intelligence techniques such as Grey Wolf Optimization (GWO), Particle Swarm Optimization (PSO), and Grasshopper Optimization Algorithm (GOA) were applied. Since the database includes 400 data, these techniques were utilized due to their effectiveness on a large set of data. In this research, using drilling data compiled from Shadegan oilfield, a precise model was developed to predict the ROP. Results showed that determination coefficient (R2) and Root mean squared error (RMSE) parameters for Particle Swarm Optimization (PSO) are found to be as R2=0.977 and RMSE=0.036, for Grey Wolf Optimization (GWO) R2=0.996 and RMSE=0.014, for Grasshopper Optimization Algorithm (GOA) R2=0.999 and RMSE=0.003, respectively. Ultimately, it can be concluded that all predictive models lead to acceptable results but GOA yields more precise and realistic outcome.
Improving the quality of visualization in phacoemulsification in the “triple procedure”
Authors: Osipyan Grigory A. , Mamikonyan Vardan R. , Shakhbazyan Nare P. , Khraistin Khusam
Published: July 2024

The so-called “triple procedure,” including penetrating keratoplasty in combination with cataract removal and posterior chamber IOL implantation, is the preferred treatment method for patients with combined pathology of the cornea and lens. Methods to reduce intraoperative complications and ensure rapid visual rehabilitation in patients with concomitant conditions are of particular importance when planning such surgeries. In this article, we describe a clinical case of a triple procedure, which involves a lamellar dissection of the damaged cornea of the recipient followed by exposure of the residual corneal stroma to a 40% glucose solution in combination with a viscoelastic, which allowed for optical clearing of the stroma and improved visualization of the anterior chamber structures for phacoemulsification with posterior chamber IOL implantation. This approach represents a safer alternative to the “cataract stage” of surgery, performed under “open sky” conditions.
Dynamics of Dental Care for the Population of the Ryazan Region in COVID-19 Pandemic
Authors: Yurina Svetlana V. , Manukhina Elena V. , Uspenskaya Irina V. , Yurin Pavel P. , Tishkina Larisa N.
Published: July 2024

INTRODUCTION: Identification of morbidity (based on requests) and the population’s need for dental care optimizes the planning and distribution of compulsory health insurance (CHI) funds between medical organizations at the regional level. However, due to a decrease in the population’s demand for medical care in the context of the new coronavirus infection (Corona Virus Disease 2019, COVID-19), the dynamics of the provision of dental care and the structure of dental morbidity taken into account in the compulsory medical insurance system, have changed.
AIM: To study the structure and dynamics of the provision of dental care in the period 2018–2021 (pre-pandemic and COVID-19 pandemic period) based on the volume of dental care paid for in the compulsory medical insurance system provided to citizens of the Ryazan region (RR).
MATERIALS AND METHODS: The analysis was carried out on the basis of registers of bills accepted for payment submitted by medical organizations, taking into account the results of control and expert measures. All completed cases of treatment of insured persons with dental diseases in medical organizations of the Ryazan Region for 2018–2021 were selected for study according to territorial compulsory medical insurance programs.
RESULTS: In the structure of outpatient primary health care in 2021, cases of its provision in the ‘Dentistry’ profile amounted to 7.40 ± 0.10%, taking 3rd place; the total number of cases of providing medical care to patients with this pathology decreased by 5.60% compared to 2018. Despite the reduction in the volume of primary dental care, the volume of dental examinations of the population of the RR increased by 30.46%. There was also a 34.08% reduction in completed cases of treatment of chronic periodontitis (p 0.02). For the 2018–2021 period 73,049 medical and economic examinations (MEE) and 1,626 examinations of medical care quality (EMCQ) were carried out, and 1,966 violations were identified (1,316 based on the results of the MEE and 650 based on the results of the EMСQ). The vast majority of these concerned non-compliance with standards of care and clinical guidelines.
CONCLUSION: The results of the study indicate a reduction in the number of cases of insured persons seeking medical care for dental diseases during the COVID-19 pandemic. Owing to the approval of Order No. 231n of the Ministry of Health of Russia of March 19, 2021, obliging medical insurance organizations to carry out control and expert measures in each medical organization in a certain amount of dental care cases accepted for payment, the number of examinations has increased, and, as a result, the identification of violations in the provision of dental care.
Tactics for Choosing Optimal Parameters of Intense Pulsed Light in Treatment of Erythematotelangiectatic Subtype of Rosacea
Authors: Zhil'tsova Elena E. , Mezhevaya Kseniya V.
Published: July 2024

INTRODUCTION: There exist several approaches to treatment of rosacea: systemic, external or complex therapy. Many practitioners note the effectiveness of using intense pulsed light in treatment of rosacea acne. Along with hardware techniques, azelaic acid-based gel is actively used in treatment. Despite the growing popularity of phototherapy, there is insufficient scientific literature on the study of optimal parameters of intense pulsed light for patients using azelaic acid.
AIM: To describe the experience of application of a combination of intense pulsed light and azelaic acid in erythematotelangiectatic subtype of rosacea.
A clinical case of a 52-year-old female patient with severe erythematotelangiectatic rosacea. Phototherapy was conducted in a course of 7 procedures with an interval of 3 weeks; azelaic-based gel was prescribed twice a day for 5 months, sunscreen cream with protection factor 50 for daily use. For the first procedure, a filter with 640 nm wave length was used, fluence 22 J/cm2, pulse duration 3.5 ms, number of subpulses — 3; filter with 590 n wavelength, fluence 22 J/cm2, pulse duration 3.5 ms, number of subpulses — 3; filter with 560 nm wavelength, fluence 20 J/cm2, pulse duration 3.5 ms, number of subpulses — 3; filter with 515 nm wavelength, fluence 16 J/cm2, pulse duration 3.5 ms, number of subpulses — 3. After 3 weeks, a second phototherapy procedure was conducted according to the same protocol. In the third procedure, the energy flow on each filter was increased by 1 J, pulse duration and number of subpulses did not change. On examination in 3 weeks, there was a reduction of the number of small and large telangiectasias, significant reduction of redness, no disturbing subjective sensations. In the subsequent procedures it was decided not to increase the energy flow on filters to avoid recurrent undesired phenomena.
CONCLUSION: Clinical observation demonstrated the effectiveness of using a combination of intense pulsed light and azelaic acid in erythematotelangiectatic rosacea when selecting the maximum permissible parameters of phototherapy. When treating with intense pulsed light it is permissible to increase the energy flow by 1 J/cm2–2 J/cm2 on condition of normal tolerance. In case edema and hyperemia are present for more than 3 days, it is necessary to reduce the energy flow.
Breast Cancer Resistance Protein: Structure, Localization, Functions, Significance for Rational Pharmacotherapy
Authors: Popova Natal’ya M. , Shchul’kin Aleksey V. , Tranova Yuliya S. , Povetko Mariya I. , Polupanov Aleksandr S. , Pravkin Sergey K. , Slepnev Alexandr A. , Yakusheva Elena N.
Published: July 2024

INTRODUCTION: Currently, investigation of efflux transport systems of an organism is an important scientific and practical task permitting to more deeply investigate the pharmacokinetics of medical drugs and to optimize pharmacotherapy of a number of diseases. The super family of ABC transporters plays a significant role in transport of biobiotics, the processes of absorption, distribution and excretion of medical drugs from an organism, in realization of undesired drug-drug interactions and development of pharmacoresistance. An important representative of this super family is breast cancer resistance protein (BCRP).
AIM: Systematization of the data on BCRP structure, localization, functions, substrates and modulators of its activity.
This literature review presents modern data on the molecular and spatial structure of BCRP, its localization in the cell, in organs and tissues. The data from studies of the functions of BCRP in an organism, of its role in the development of undesired drug-drug interactions at different stages of pharmacokinetics are summarized. An up-to-date list of medicinal drugs that are substrates and inhibitors of BCRP is given. Modern approaches to testing medical drugs for belonging to BCRP substrates or modulators of its activity are disclosed.
CONCLUSION: The significance of BCRP consists in the existence of a wide range of drugs that are its substrates or modulators of its activity. Upon that, of increasing significance is the investigation both of new and long-known medicinal substances for their belonging to substrates, inducers or inhibitors of breast cancer resistance protein, in order to increase the effectiveness of pharmacotherapy and reduce the risk of undesired drug interactions. Search for non-drug substrates and modulators of BCRP activity permits to obtain new markers for conducting effective studies of safe pharmacokinetics both in vitro and in vivo.
Modern Trends in Development of Educational and Scientific Discipline ‘Public Health and Healthcare’: Its Methodological Role and Integrative Function
Authors: Kagramanyan Igor’ N. , Reshetnikov Vladimir A. , Manerova Ol'ga A. , Yakushina Irina I. , Shustikova Elena A. , Ismail-zade Nazim T. ogly
Published: July 2024

INTRODUCTION: In modern conditions of social development, there is a change of emphasis in definitions concerning not only public, but also individual health. Preserving and strengthening the health of the population is a complex task that implies the interaction of various specialists. This integration, the complexity of interaction in issues concerning preserving and strengthening the health of the population, should undoubtedly be reflected in the training of specialists, and, first of all, in higher medical education.
AIM: To determine the role of the discipline ‘Public Health and Healthcare’ (PHH) in teaching population health issues and in the integration of departments of various profiles in the study of individual, group and population health in modern conditions.
The article presents a discussion about modern trends in the development of the educational and scientific PHH discipline based on the opinions of students, teachers and the experience of Sechenovskiy University. Thus, students of profiles ‘General Medicine’, ‘Pediatrics’, ‘Medical and Preventive Care’ think that studying public health issues is the task of doctors of all clinical specialties (69.4%–76.7%), of hygienists ( 60.0%), of epidemiologists ( 30.0%). Integration in the teaching of PHH issues, according to teachers of PHH departments, in such types of activities as academic work, educational work, general scientific projects, joint printed works, textbooks and teaching aids, joint innovative projects, is mainly carried out with teachers of preventive educational disciplines, to a much lesser extent with teachers of clinical and fundamental disciplines.
CONCLUSION: An integrative approach to definitions, terms, and concepts is needed in the study of the health of individuals, population groups and population with a significant variety of disciplines and departments teaching them. The methodological role in teaching these issues is the prerogative of the PHH discipline.
Sustaining Integrity: The Role of Education and Macroeconomic Variables for Corruption Eradication
Authors: Susilowati Indah , Negara Andi Kurniawan Karta , Anam Muhammad Syariful , Zaakiyyah Hizbul Khootimah Az , Sakinah Ramadhanti Dara , Furoida Aini Nur
Published: July 2024

This study aims to analyze the effect of education level and several macroeconomic variables on the corruption index in Asia-Pacific Economic Cooperation (APEC) member countries. This study uses the two-stage least square (2SLS) estimation method. This study found that the lifelong learning index, higher education participation, and foreign direct investment have a negative and significant effect on corruption in all APEC member countries and developing country members. Secondary education  and government efficiency index have a negative and significant effect on corruption in all  countries (all member states, developed and developing  countries). GDP per capita and economic openness have a positive and significant effect on corruption levels in APEC member states and developing countries. The fight against corruption must be immediately implemented as a political influence. Delaying this will reduce the effectiveness of future policies. Institutional reforms bring more positive benefits in countries that are really fighting corruption.
Technology Support for the Inclusion of Deaf Students in Special School Sukabumi City
Authors: Nugraha Deden Novan Setiawan , Hermina Nurul
Published: July 2024

The COVID-19 pandemic brought rapid changes in various areas of life, including education and technology. One of the learning media that the deaf can use to improve their ability to compose sentence structures is I-CHAT (I Can Hear and Talk). I-CHAT is a portal that contains applications that function as tools for the deaf in language acquisition. In communicating, mastery of sentence structure is crucial. It is because with the correct sentence structure, other people will better understand what we are talking about, and besides that, communication becomes more effective and efficient. Communication barriers that occur in deaf children are caused by hearing impairment, which ultimately requires deaf children only to use sight to acquire their receptive language. This has an impact on the acquisition of imperfect or partial deaf children's receptive language because not everything they see can be understood. Therefore, if a deaf child makes a sentence, the sentence structure is sometimes wrong. This research aims to determine the use of I-CHAT in the preparation of sentence structures for deaf students at Inclusive School Sukabumi City. This research is experimental with a quantitative approach. The results of the research show that the use of I-CHAT can improve the ability to compose sentence structures for deaf children in Special School Sukabumi City.