bluuebunny/crossref_metadata_2025 huggingface dataset:
Taxonomic study of the leafhopper genus Salka Dworakowska (Hemiptera: Cicadellidae: Typhlocybinae: Erythroneurini) from China, with descriptions of seven new species
Authors: LIN SHUANGHU , ZOU HONGFEN , HUANG MIN , ZHANG YALIN
Published: January 2023

The genus Salka Dworakowska is reviewed with seven new species described from China: S. aequilonga, S. delphiura, S. dipteriga, S. lamellipenia, S. limboserrata, S. longipenia and S. taopenna spp. nov. Detailed morphological descriptions and illustrations of these seven new species and a key to all known species (males) from China are provided.
A review of Vietnamese Scolopocryptops Newport, 1844 (Chilopoda: Scolopendromorpha), with a description of S. hoanglieni n. sp. and the updated generic list of species
Authors: LE SON X. , SCHILEYKO ARKADY A. , NGUYEN ANH D.
Published: January 2023

The Vietnamese fauna of the genus Scolopocryptops Newport, 1844 was reviewed based on recently collected specimens and material from Zoological Museum of the Moscow Lomonosov State University (ZMMU) and Naturhistorisches Museum Wien (NHMW). As a result of study of 164 specimens from 13 sampling regions, four species have been recognized, of which S. rubiginosus C.L. Koch, 1878 and S. spinicaudus Wood, 1862 already reported from Vietnam, S. hoanglieni described as n. sp., and S. capillipedatus (Takakuwa, 1938) for the first time recorded for this country. S. broelemanni esulcata Attems, 1938 was redescribed and confirmed as a valid. The COI fragments were obtained for the above mentioned species and the K2P genetic divergence between Vietnamese Scolopocryptops species was preliminarily estimated. New data on intraspecific variations of spiracle number in Scolopocryptops, an identification key for East Asian species and the general list of species of Scolopocryptops are provided.
New specimens and supplementary descriptions of two rare dragonfishes, Photonectes klepadloae and P. litvinovi, with comments on the distribution of P. filipendulus (Teleostei: Stomiidae: Melanostomiinae)
Authors: PROKOFIEV ARTEM M. , FRABLE BENJAMIN W.
Published: January 2023

Supplementary descriptions based on new specimens of two rare dragonfish species, Photonectes klepadloae and P. litvinovi, formerly known by the holotypes only, are presented. The presence of a bulbous swelling at the tip of the terminal filament of the mental barbel is documented for P. klepadloae, and its absence in some specimens of that species, including the holotype, is likely an artifact of preservation. The presence of blue luminous tissue is documented for P. litvinovi, which was formerly believed to lack it due to skin abrasion in the holotype. A key for the species is corrected based on the new diagnostic characters of P. litvinovi. Incorrect mapping of the distribution of P. filipendulus provided in the original description is improved and a map showing the known distribution of all three aforementioned species is presented.
A new species of Euconocephalus Karny, 1907 (Orthoptera: Tettigoniidae: Conocephalinae: Copiphorini) from India
Authors: KUMAR HIRDESH , CHAND D. SURESH , RAGHUNATHAN C. , BANERJEE DHRITI
Published: January 2023

A new species, Euconocephalus narayanpurensis Kumar & Chand sp. nov., from India is described in this paper. The new species is similar to the African species Euconocephalus lineatipes (Bolívar, 1890), but differs from the latter in the smaller size, more acute humeral sinus, the narrowly rounded apex of elytra and convex male last abdominal tergite. A key to the Indian species of Euconocephalus Karny, 1907 is also provided.
Application of Dual-Drug Loaded Metal Organic Framework Nanomaterials Targeting PI3K Signaling Pathway in Triple Negative Breast Cancer Cells
Authors: Huang Qianfang , Wu Nanchang , Chen Miao , Lv Zheng , Wang Jing
Published: January 2023

Aim: To design a new treatment based AKT inhibitor (MLF), as a therapeutic target, and doxorubicin, as a chemotherapy agent, co-loaded on Modern metal organic frameworks (MFOs) by using ZIF-8 nanomaterials. Methods: We synthesized a MOFs (ZIF-8) as a drug carrier, and
achieved simultaneous loading of the chemotherapeutic drug DOX and AKT inhibitor MFL (ZIF-8/DOX/MFL), as a drug carrier. In addition, we used MTT assay, evaluation the expression of collagen-1, and tumor drug uptake to evaluate the efficacy of our treatment. We further used ultrasound to modify
the red blood cell membrane on the surface of ZIF-8/DOX/MLF to improve the biological safety and stability of the drug-carrying system, and finally obtained ZIF-8/DOX/MLF/RBCM. Results: Our results showed that the tumor enrichment in the ZIF-8/MLF/RBCM group was about 3 times that of
the ZIF-8/RBCM group; and both in vivo and in vitro imaging of mouse organs showed that MLF has the function of assisting drug delivery and enhancing drug tumor enrichment, according to fluorescence quantification. Conclusion: The research results show that the ZIF-8/DOX/MLF/RBCM
can achieve the purpose of sensitizing new tumor chemotherapy in breast cancer.
PRSS1 Mutations Affect Pancreatic Ductal Adenocarcinoma Radiosensitivity via AKT and Extracellular Regulated Protein Kinases Pathways
Authors: Ke Chunlin , Cai Chuanshu , Wang Peirong , Dong Feng
Published: January 2023

Radioresistance is the leading cause of failed radiation therapy for pancreatic ductal cancer (PDAC). The relevance of the cationic trypsinogen gene (PRSS1) in PDAC radioresistance is unknown, despite its association with tumor responses to therapy in numerous malignancies. Here we
established two PRSS1 point mutation PDAC cell lines: c. 338 T > G and c.410 C > T. Compared to their parental cells, elevated AKT and ERK phosphorylation concentrations were observed in Panc-1 and MIA PaCa-2 c. 338 T > G and c.410 C > T cells with point mutations. The PRSS1 mutation
restored the sensitivity of radioresistant cells to radiation through increased ionizing radiation-induced apoptosis by down regulating p-AKT and p-ERK. Based on these results, we hypothesized that a PRSS1 mutation in PDAC increased cell radiosensitivity by decreasing p-AKT and p-ERK. Our
findings provide a molecular basis for optimizing radiation in patients with PDAC.
Calcium Phosphate Functionalization and Applications in Dentistry
Authors: Lu Zi-qian , Ren Qian , Han Si-li , Ding Long-jiang , Li Zhong-cheng , Hu Die , Wang Luo-yao , Zhang Ling-lin
Published: January 2023

The oral and maxillofacial hard tissues support the maxillofacial shape and serve as the foundation for functional activities. Defects in these tissues not only impair patients’ ability to perform their normal physiological functions but also have a significant negative impact on their psychological well-being. Moreover, these tissues have a limited capacity for self-healing, necessitating the use of artificial materials to repair defects. Calcium phosphate is a fine-grained inorganic biomineral found in vertebrate teeth and bones that has a comparable composition to human hard tissues. Calcium phosphate materials are biocompatible, bioactive, and osteogenic for hard tissue repair, despite drawbacks such as poor mechanical qualities, limiting their clinical efficacy and application. With the advancement of materials science and technology, numerous techniques have been developed to enhance the characteristics of calcium phosphate, and one of them is functionalization. Calcium phosphate can be functionally modified by changing its size, morphology, or composition through various preparation processes to achieve multifunctionality and improve physical and chemical properties, biocompatibility, and osteogenic potential. The purpose of this review is to provide new ideas for the treatment of oralmaxillofacial hard tissue defects and deficiencies by summarizing the functionalization strategies of calcium phosphate materials and their applications in dentistry.
Analysis of Expression of Diabetic Nephropathy-Related Protein and Stem Cell Tissue Repair Under Nano Membrane Concentration Technology
Authors: Zhao Lingxia , Liu Shiwei , Zhang Yuanlin , Fan Xuemei , Xue Xuehua , Li Qingxia , Zhuang Xiaofei , Zheng Guoping
Published: January 2023

This study aimed to study protein expression in diabetic nephropathy (DN) rats and stem cell tissue repair based on nanomembrane concentration technology. Based on the polymer porous self-assembled nanomembrane technology, the content of total protein and albumin in the serum of rats
in the control and experimental groups were measured. The obtained images were adopted to analyze the expression of cytoplasmic proteins and membrane proteins, and then the mechanism of stem cell tissue repair function was studied. The results showed that at 56 weeks of age, in contrast to
control group, the total protein content in the serum of the experimental group evidently decreased. At 36 weeks of age, the cytoplasmic protein samples of diabetic rats in the experimental group were subjected to three two-dimensional protein electrophoresis. It was found that there were
about 701 spots in each gel, and the matching rate was about 87.5%. In contrast to control group, 16 cytoplasmic proteins and 23 membrane proteins of the experimental group changed. The results of the differentially expressed protein analysis indicated that the change trends of protein spots.
Based on polymer porous self-assembled nano-film technology, the expression of differential proteins in DN rats was analyzed, which would supplement new research assistance to the mechanism of DN.
Lodoxamide-Loaded Nanofibrous Wound Dressings Promote Wound Healing via Downregulation of IL-1β, NFK-β, and GPx Genes
Authors: Mi Zengfa , Tofighi Ehsan
Published: January 2023

Diabetic wounds are major clinical challenges which need immediate care to prevent complications such as limb amputation. There are a variety of treatment strategies available for the treatment of diabetic wounds among which wound dressings are the most effective and provide better
therapeutic outcome. Lodoxamide was loaded into gelatin scaffolds in order to develop a potential wound dressing material for diabetic wound healing. Electrospinning method was used for the fabrication of wound dressings containing three different concentrations of 1 w/w%, 3 w/w%, and 6 w/w%
of Lodoxamide. The developed scaffolds were studied regarding their various physicochemical and biological properties. In vitro study showed that the dressings containing 3% drug had significantly higher cell viability and cytoprotection under oxidative stress. Therefore, this formulation
was chosen for treating diabetic wounds in a rat model of excisional diabetic wound. In vivo study showed that gelatin/3% Lodoxamide group had higher wound healing compared with other experimental groups. Gene expression studies showed that the wounds treated with drug-delivering wound
dressings showed significantly lower tissue expression level of glutathione peroxidase gene, IL-1β gene, and NFK-β gene.
Phototoxic Effect of UVA-Responsive Fe3O4@ZnO Nanoparticles on Squamous Skin Cell
Authors: Ren Qian , Liu Wei , Bai Qing-Ping , Huang Yong , Pan Jun , Samina Ejaz , Huang Xiao
Published: January 2023

Zinc oxide (ZnO) is a resource-rich metal oxide with a certain degree of phototoxicity toward cancer cells using ultraviolet light radiation. Therefore, it is a promising photosensitizer for photodynamic therapy against cancer. The current study synthesized core-shell structure nanoparticles
using Fe3O4 as the core and ZnO as the shell. The core–shell nanoparticles were spherical-like and superparamagnetic, with a zeta potential of −22.7±7.6 mV. ZnO-coated ferroferric oxide nanoparticles (Fe3O4@ZnO NPs) under ultraviolet
A (UVA) irradiation could induce a lot more reactive oxygen species in the squamous skin cells causing the evident inhibitory effect. In contrast, they indicated no toxicity to skin squamous cells without UVA radiation. Therefore, it can be inferred that their great potential as the targeting
photosensitizer for photodynamic therapy on skin squamous cell carcinoma is due to their good biocompatibility without UVA radiation and excellent toxicity under UVA radiation on skin squamous cells.
Nanofibrous Wound Healing Nanocomposite Based on Alginate Scaffold: In Vitro and In Vivo Study
Authors: Hu Enyi , Liang Yihui , Chen Kangcha , Li Xian , Zhou Jianhui
Published: January 2023

The combination of nanofibers with 3D scaffolds has shown promising results as the wound healing/dressing/care biomaterials. The present study aimed to fabricate and optimized alginate hydrogel composited by Lignin-derived carbon nanofibers (CNFs). The nanofibers were obtained from
electrospun Lignin nanofibers as the precursor through two steps heat treatments. The synthesized nanofibers blended with an alginate polymer solution with different concentrations (1, 5, and 10 wt.%) and cross-linked using CaCl2 through the physical cross-linking. The findings
illustrated that the prepared Lignin and CNFs have acceptable diameter. The composited Alginate hydrogels possessed a porous internal-structure with interconnected architecture. The fabricated hydrogel exhibited proper porosity and swelling behavior beneficial for wound healing application.
The In Vitro experiments revealed that the hydrogel were red blood cell (RBC)-compatible, cytocompatible, and induced proliferative effects on cells. The animal experiments indicated that the application of the hydrogel promoted the process of wound healing. These observations implied
that the prepared hydrogel nanocomposites exhibited promising properties and can be considered as wound healing nanobiomaterials.
Preparation of Triptolide Nano Drug Delivery System and Its Antitumor Activity In-Vitro
Authors: Qin ZhongHua , Yu GuiPing , Li Ran , Zhao Jun
Published: January 2023

Triptolide (as an effective antitumor drug) is limited in clinical application because of its poor solubility and absorption in-vivo. Herein, we prepared folic acid modified polymer micelles to encapsulate triptolide and enhance its biologicalavailability coupled with antitumor
effect. We prepared nano-micelles of triptolide through thin lipid film hydrational method. Physical properties and in vitro release characterization of Fol-Plla-cl-Peg-Plla-cl-Tmicelles were evaluated, while bioavailability of the formulation in rats was investigated. Tumor targeting
potential of micelles was determined by observing the uptake of A549 cells. In-Vitro antitumor activity of micelles and free triptolide (API) was investigated with MTT assay. The prepared polymer material exhibited no cytotoxicity. The particle size distribution of Fol-Plla-cl-Peg-Plla-cl-T
micelles was uniform and small, with good stability and high efficiency of entrapment. Triptolide In-Vitro release from micelles demonstrated slow and continuous released for 24 h. Compared with API, the half-life of micelles was prolonged, whilst its bioavailability in-vivo
was increased by about 6.35 times. More importantly, Fol-Plla-cl-Peg-Plla-cl-T micelles significantly improved the antitumor activity of triptolide and showed good tumor targeting potential. Fol-Plla-cl-Peg-Plla-cl-T micelles could improve the bioavailability and antitumor activity of triptolide,
amid demonstration of good tumor targeting and high safety.
Exosomes Secreted from Mesenchymal Stem Cells Carry miR-486-5p to Inhibit Cell Proliferation and the Epithelial-Mesenchymal Transition Process to Treat Human Lung Cancer by Down-Regulating MIER3
Authors: Peng Jingcui , LI Sa , LI Bin , Hu Wenxia , Ding Cuimin
Published: January 2023

Exosomes are nano-vesicles that can shuttle active cargoes. Mesenchymal stem cells play a complex function in tumour progression.We investigated the effect of miR-486-5p, an exosome of human bone marrow-derived MSCs on lung cancer. We found that miR-486-5p, carried in mesenchymal stem
cells and mesenchymal stem cell-derived exosomes, regulates MIER3 expression by binding to its 3’UTR, thereby inhibiting the epithelial-mesenchymal transition process of A549 cells. In vivo, we demonstrated that exosome treatment reduced the area of tumour necrosis, increased
the expression of miR-486-5p and inhibited the epithelial–mesenchymal transition process in mice. In conclusion, mesenchymal stem cell-derived exosomal miR-486-5p directly and negatively targets MIER3 to inhibit lung cancer.
The Intervention of the Anti-Extradition Bill Movement in the Norms of Citizenship in Hong Kong
Authors: Tang Gary
Published: January 2023

Following the post-material shift of post-industrial societies, an evolution in citizenship norms from dutiful citizenship to engaged citizenship has occurred. This paper examines how people’s attitudes towards the Anti-Extradition Bill movement are related to these two citizenship norms. Using data collected from a population survey ( N = 817), this paper shows that the people supporting the movement and radicalism perceived dutiful citizenship to be less important and engaged citizenship to be more important. The compatibility between the two sets of citizenship was found to be stronger among the people who supported the movement, despite the frequent appearance of unlawful behaviour in the movement. To explain the moderating effect, observations from focus group interviews revealed that some people had a traumatic experience in the movement. This trauma led them to doubt the legitimacy of the authority. Therefore, although they perceived dutiful citizenship to be important, they could also support various unlawful behaviours that occurred in the movement.
Does Loyalty Discourage Exit? Evidence from Post-2020 Hong Kong
Authors: Wong Stan Hok-Wui , Ho Karl , Clarke Harold D. , Chan Kelvin Chun-man
Published: January 2023

In his seminal book Exit, Voice, and Loyalty, Hirschman suggests that loyal members are less likely to exit when dissatisfied with the performance of the organization. In the context of a political regime, however, we argue that loyalty may actually encourage exit because loyal members are more sensitive to the performance decline of the regime. Using an original survey conducted in Hong Kong, we show that survey respondents with a stronger local identity have greater migration intentions. We also find that the heterogeneity of perceived political changes plays a significant role as a mediator. We discuss the political implications for Hong Kong.
After State Repression: Movement Abeyance in Hong Kong under the Enforcement of the National Security Law
Authors: Kwong Ying-Ho
Published: January 2023

The Chinese government has imposed the National Security Law which has resulted in Hong Kong formally entering into a phase of movement abeyance. By analysing 3377 posts on LIHKG Internet forum, this article re-explores the online protest attitude during this movement abeyance. The findings indicate that content creators are more attentive in regard to criticizing the legislation and pro-Beijing figures, followed by seeking international support and calling for unity. Users are more ‘participative’ in calling for mutual destruction between the authorities and people, initiating mutual support and seeking emigration. This study provides new perspectives on the study of movement abeyance.
Hong Kong and the 2019 Anti-Extradition Bill Movement
Authors: Wang T.Y.
Published: January 2023

The 2019 Anti-extradition Law Amendment Bill Movement is the largest series of protests in Hong Kong’s history. This Special Issue includes eight articles written by experts. It aims to examine recent developments in Hong Kong, their impacts on the society, and implications to the city’s future.
Transnational Activism During Movement Abeyance: Examining the International Frontline of Hong Kong’s 2019 Anti-Extradition Bill Movement
Authors: Shum Maggie
Published: January 2023

Why does the Hong Kong diaspora mobilize transnationally to support the Anti-ELAB Movement back home? How do overseas mobilizations help sustain movement during its abeyance period? Building on the theoretical grounding from transnational movement and diaspora studies, I identify four dimensions of transnational ties that diasporas have with their homeland—relational, political, cultural, and identity and value—and examine their effect on diasporic activism in the host countries. Using original survey data on Hong Kong Americans and interviews with members of overseas Hongkonger groups, I demonstrate that attachment to Hong Kong culture and localist values are the strongest drivers for transnational engagement.
Healthcare professionals’ perception of barriers and facilitators for care coordination of older adults with complex care needs being discharged from hospital: A qualitative comparative study of two Nordic capitals
Authors: Agerholm Janne , Jensen Natasja Koitzsch , Liljas Ann
Published: January 2023

Background

The handover of older adults with complex health and social care from hospital admissions to homebased healthcare requires coordination between multiple care providers. Providing insight to the care coordination from healthcare professionals’ views is crucial to show what efforts are needed to manage patient handovers from hospitals to home care, and to identify strengths and weaknesses of the care systems in which they operate.

Objective

This is a comparative study aiming to examine healthcare professionals’ perceptions on barriers and facilitators for care coordination for older patients with complex health and social care needs being discharged from hospital in two capital cities Copenhagen (DK) and Stockholm (SE).

Method

Semi-structured interviews were conducted with 25 nurses and 2 assistant nurses involved in the coordination of the discharge process at hospitals or in the home healthcare services (Copenhagen n = 11, Stockholm n = 16). The interview guide included questions on the participants’ contributions, responsibilities, and influence on decisions during the discharge process. They were also asked about collaboration and interaction with other professionals involved in the process. The data was analysed using thematic analysis.

Results

Main themes were communication ways, organisational structures, and supplementary work by staff. We found that there were differences in the organisational structure of the two care systems in relation to integration between different actors and differences in accessibility to patient information, which influenced the coordination. Municipal discharge coordinators visiting patients at the hospital before discharge and the follow-home nurse were seen as facilitators in Copenhagen. In Stockholm the shared information system with access to patient records were lifted as a facilitator for coordination. Difficulties accessing collaborators were experienced in both settings. We also found that participants in both settings to a high degree engage in work tasks outside of their responsibilities to ensure patient safety.

Conclusions

There are lessons to be learned from both care systems. The written e-communication between hospitals and home health care runs more smoothly in Stockholm, whereas it is perceived as a one-way communication in Copenhagen. In Copenhagen there are more sector-overlapping work which might secure a safer transition from hospital to home. Participants in both settings initiated own actions to weigh out imperfections of the system.
Nesting the SIRV model with NAR, LSTM and statistical methods to fit and predict COVID-19 epidemic trend in Africa
Authors: Liu Xu-Dong , Wang Wei , Yang Yi , Hou Bo-Han , Olasehinde Toba Stephen , Feng Ning , Dong Xiao-Ping
Published: January 2023

Objective

Compared with other regions in the world, the transmission characteristics of the COVID-19 epidemic in Africa are more obvious, has a unique transmission mode in this region; At the same time, the data related to the COVID-19 epidemic in Africa is characterized by low data quality and incomplete data coverage, which makes the prediction method of COVID-19 epidemic suitable for other regions unable to achieve good results in Africa. In order to solve the above problems, this paper proposes a prediction method that nests the in-depth learning method in the mechanism model. From the experimental results, it can better solve the above problems and better adapt to the transmission characteristics of the COVID-19 epidemic in African countries.

Methods

Based on the SIRV model, the COVID-19 transmission rate and trend from September 2021 to January 2022 of the top 15 African countries (South Africa, Morocco, Tunisia, Libya, Egypt, Ethiopia, Kenya, Zambia, Algeria, Botswana, Nigeria, Zimbabwe, Mozambique, Uganda, and Ghana) in the accumulative number of COVID-19 confirmed cases was fitted by using the data from Worldometer. Non-autoregressive (NAR), Long-short term memory (LSTM), Autoregressive integrated moving average (ARIMA) models, Gaussian and polynomial functions were used to predict the transmission rate β in the next 7, 14, and 21 days. Then, the predicted transmission rate βs were substituted into the SIRV model to predict the number of the COVID-19 active cases. The error analysis was conducted using root-mean-square error (RMSE) and mean absolute percentage error (MAPE).

Results

The fitting curves of the 7, 14, and 21 days were consistent with and higher than the original curves of daily active cases (DAC). The MAPE between the fitted and original 7-day DAC was only 1.15% and increased with the longer of predict days. Both the predicted β and DAC of the next 7, 14, and 21 days by NAR and LSTM nested models were closer to the real ones than other three ones. The minimum RMSEs for the predicted number of COVID-19 active cases in the next 7, 14, and 21 days were 12,974, 14,152, and 12,211 people, respectively when the order of magnitude for was 106, with the minimum MAPE being 1.79%, 1.97%, and 1.64%, respectively.

Conclusion

Nesting the SIRV model with NAR, LSTM, ARIMA methods etc. through functionalizing β respectively could obtain more accurate fitting and predicting results than these models/methods alone for the number of confirmed COVID-19 cases in Africa in which nesting with NAR had the highest accuracy for the 14-day and 21-day predictions. The nested model was of high significance for early understanding of the COVID-19 disease burden and preparedness for the response.
Delta large-channel technique versus microscopy-assisted laminar fenestration decompression for lumbar spinal stenosis: a one-year prospective cohort study
Authors: Sheng Yuehang , Li Jing , Chen Lei , Geng Minghao , Fen Jing , Sun Shaodong , Sun Jianhua
Published: January 2023

Purpose

When it comes to treating lumbar spinal stenosis (LSS), a procedure known as microscope-assisted fenestration decompression has expediently become the gold standard. With the advancement of spinal endoscopy, the Delta large-channel approach has shown promising clinical outcomes in the management of lumbar spinal stenosis. However, case studies of this method being used to treat lumbar spinal stenosis are still uncommon. The purpose of this research was to examine how well microscopy-assisted laminectomy and the Delta large-channel approach work in treating LSS in the clinic.

Methods

From May 2018 to June 2020, 149 patients diagnosed with LSS were divided into 80 patients in Delta large-channel technique groups (FE group) and 69 patients in microscope groups (Micro group). Lower back and lower limb pain were measured using the visual analogue scale (VAS-LBP and VAS-LP), while lower limb numbness was evaluated using the 11-point numerical rating scale (NRS-LN); modified Oswestry Disability Index (ODI) was used to evaluate the quality of life, and modified MacNab criteria were used to assess the clinical efficacy before surgery and at one week, three months, six months, and 12 months after surgery. All patients had single-level lumbar spinal stenosis, and clinical data such as hospital stay, operation time, intraoperative blood loss were statistically analyzed.

Results

Finally, 111 patients (62 in FE group and 49 in Micro group) completed follow-up. Compared with preoperative results, postoperative VAS-LBP, VAS-LP, NRS-LN score and modified ODI score were significantly improved in 2 groups (P < 0.05), but there was no significant difference in postoperative follow-up at each time point (P > 0.05), Except 1 week after surgery, VAS-LBP in FE group was lower than that in Micro group (P < 0.05). It is noteworthy that the FE group had a shorter hospital stay, less intraoperative blood loss, and a quicker time of getting out of bed when compared with the microscope group，but the operation time was just the opposite (P < 0.05). The excellent and good rate was 83.87% in FE group and 85.71% in Micro group (P > 0.05).

Conclusions

Both microscope-assisted laminar fenestration decompression and Delta large-channel procedures provide satisfactory treatment outcomes, however the Delta large-channel approach has some potential advantages for the treatment of LSS, including quicker recovery and sooner reduced VAS-LBP. Long-term consequences, however, will necessitate additional follow-up and research.
Differences in the prevalence and risk factors of osteoporosis in chinese urban and rural regions: a cross-sectional study
Authors: Zheng Miao , Wan Yanan , Liu Gongwen , Gao Yan , Pan Xiaoqun , You Wanxi , Yuan Donglan , Shen Jianxin , Lu Junhua , Wang Xia , Zheng Gangfeng , Han Zhiqiang , Li Xinlin , Chen Kai , Xing Xiaoxi , Zhang Dong , Weng Chengwei , Wei Qi , Zhang Yongqing , Lin Hua
Published: January 2023

Background

Bone mineral density (BMD) and prevalence of osteoporosis may differ between urban and rural populations. This study aimed to investigate the differences in BMD characteristics between urban and rural populations in Jiangsu, China.

Methods

A total of 2,711 participants aged 20 years and older were included in the cross-sectional study. Multistage and stratified cluster random sampling was used as the sampling strategy. BMD was measured by the method of dual-energy x-ray absorptiometry (DXA). Data were collected through questionnaires/interview. BMD values at the lumbar spine (L1-L4), femoral neck, total hip, and greater trochanter were collected. Descriptive statistics were used to demonstrate the characteristics of urban and rural participants. Multivariate logistic regression analysis was utilized to analyze the factors that may be associated with osteoporosis in urban and rural populations.

Results

Of these participants, 1,540 (50.49%) were females and 1,363 (42.14%) were from urban. The prevalence of osteoporosis in urban and rural populations was 5.52% and 10.33%, respectively. In terms of gender, the prevalence of osteoporosis was 2.68% in males and 13.82% in females. For menopausal status, the prevalence of osteoporosis was 30.34% in postmenopausal females and 4.78% in premenopausal females. In urban populations, older age [adjusted odds ratio (AOR) = 2.36, 95%CI, 2.35–2.36), hypertension (AOR = 1.37, 95%CI, 1.36–1.37), unmarried (AOR = 4.04, 95%CI, 3.99–4.09), smoking everyday (AOR = 2.26, 95%CI, 2.23–2.28), family history of osteoporosis (AOR = 1.66, 95%CI, 1.65–1.67), dyslipidemia (AOR = 1.05, 95%CI, 1.04–1.05), and higher β-crosslaps (β-CTX) level (AOR = 1.02, 95%CI, 1.02–1.02) were associated with an increased risk of osteoporosis, while males (AOR = 0.04, 95%CI, 0.04–0.04), higher education level (AOR = 0.95, 95%CI, 0.95–0.95), and aquatic product intake (AOR = 0.99, 95%CI, 0.99–0.99) were related to decreased risk of osteoporosis. Similar results were also observed in rural populations, and (allP < 0.05).

Conclusion

The prevalence of osteoporosis in rural populations was higher than that in urban populations, and the factors associated with the risk of osteoporosis were similar in urban and rural populations.
Breastfeeding practices and associations with pregnancy, maternal and infant characteristics in Australia: a cross-sectional study
Authors: Reynolds Renee , Kingsland Melanie , Daly Justine , Licata Milly , Tully Belinda , Doherty Emma , Farragher Eva , Desmet Clare , Lecathelinais Christophe , McKie Julianne , Williams Melanie , Wiggers John , Hollis Jenna
Published: January 2023

Background

Exclusive breastfeeding to six months of age is a major global public health priority. Several characteristics are known to be associated with early cessation of breastfeeding, however, limited evidence exists regarding whether women’s reported reasons for cessation are associated with maternal, pregnancy and infant characteristics. The aims of this study were to: i) describe women’s reported intention to breastfeed and their subsequent breastfeeding practices; ii) describe women’s reported reasons for breastfeeding cessation prior to the infant being five months of age; and iii) examine associations between these factors and maternal, pregnancy and infant characteristics.

Methods

Telephone and online surveys were conducted between October 2019 and April 2020 with 536 women who had given birth in the previous eight to 21 weeks at four public maternity services in Australia.

Results

The majority of women intended to (94%), and did, initiate (95%) breastfeeding. At the time the survey was conducted, 57% of women were exclusively breastfeeding. Women who: had less than University level education, had a pre-pregnancy BMI in the overweight or obese category, and who smoked tobacco at the time of the survey had lower odds of exclusively breastfeeding. The most common self-reported reasons for breastfeeding cessation were breastfeeding challenges (47%) and low milk supply (40%). Women aged 26–35 years and 36 + years had greater odds of reporting breastfeeding cessation due to low milk supply (OR = 2.92, 95% CI: 1.11, 7.66; OR = 5.57, 95% CI: 1.70, 18.29) compared to women aged 18–25 years. While women who had completed a TAFE certificate or diploma had lower odds of reporting this as a reason for breastfeeding cessation (OR = 0.28; 95% CI: 0.11, 0.73) compared to women who had University level education. There were no other significant associations found between characteristics and reasons for ceasing breastfeeding.

Conclusions

The most common reasons for breastfeeding cessation may be modifiable through the provision of breastfeeding support in the early postpartum period, with such support being tailored to women’s age and level of education. Such support should aim to increase women's self-efficacy in breastfeeding, and be provided from the antenatal period and throughout the first six months postpartum.
Spinopelvic dissociation: extended definition, physical examination, classification, and therapy
Authors: Shi Bin , Peng Ye , Zhang Gongzi , Zhang Shuwei , Luo Yang , Lv Faqin , Hu Ying , Zhang Lihai
Published: January 2023

Background

Spinopelvic dissociation (SPD) is generally caused by high-energy injury mechanisms, and, in the absence of timely diagnosis and treatment, it can lead to chronic pain and progressive deformity. However, SPD is difficult to manage because of its rarity and complexity. In this study, we re-defined SPD according to the mechanism of injuries and biomechanical characteristics of the posterior pelvic ring and developed new classification criteria and treatment principles based on the classification for SPD.

Methods

Between June 2015 and September 2020, 30 patients with SPD which were selected from 138 patients with pelvic fractures were enrolled. Physical examination was performed, classification criteria (301 SPD classification) were developed, and specific treatment standards were established according to the classifications.

Results

The injury mechanisms and co-existing injuries did not significantly differ between the classical SPD patients and expanded SPD patients. The 301 SPD classification criteria covered all the patients. Fixation by biplanar penetration screws was used in 7 patients, 11 patients received fixation by uniplanar penetration screws, 6 patients used sacroiliac compression screws, 3 patients received uniplanar screws combined with sacroiliac compression screws, and open spondylopelvic fixation was used in only 3 patients. According to the Matta criteria, 19, 7, and 4 patients achieved excellent, good, and fair reduction. The Majeed function score of the patients ranged from 9 to 96 points, and the mean score was 72.9 ± 24.6 points.

Conclusion

The expanded definition for SPD is particularly significant for definite diagnosis and prevention of missing diagnosis, based on which the 301SPD classification criteria can more systemically guide the clinical treatment of SPD, increase the treatment efficacy, and reduce surgical trauma.

Chinese Clinical Trial Registry: ChiCTR-IPR-16009340.
Intra thoracic extra pulmonary hydatidosis: prognosis and outcomes of 8 operated patients
Authors: Machboua A. , Elhani F. Z. , Marouf R.
Published: January 2023

Hydatid cyst disease is a parasitic disease known from the times of hippocrates, and is still endemic in our country Morocco among others, affecting mainly the liver and lungs, while intra thoracic extra pulmonary location remains a rare entity of the disease. In our department of thoracic surgery, Mohamed VI University Hospital, Oujda, Morocco, we operated 92 patients for thoracic hydatid cyst in the period between January 2016 and December 2021, 8 patients of this group had exclusive extra pulmonary location of the hydatid cyst, epidemiological and clinical data were recorded for the 8 patients (5 men, 3 women). The mean age was 40.3 years, all patients presented mainly with chest pain, dyspnea and cough. The locations of the hydatid cysts were chest wall, pericardium, pleural space and diaphragm. The hydatid cysts were removed via extirpation technique through thoracotomy in all patients. The average duration of hospitalization was 7 days. Postoperative complications consisted of atelectasis in one patient, parietal hematoma in another, and surinfection with pleuro-cutaneous fistula and chronic neurological chest pain in one patient. No deaths were noted in our series.
Hyperglycaemia in pregnancy and offspring blood pressure: a systematic review and meta-analysis
Authors: Zhang Xinyue , Wang Yinlin , Xiao Wenhan , Jiang Denan , Zhou Jiali , Ye Xinxin , Wu Shiqi , Li Shuting , Song Peige
Published: January 2023

Background

Hyperglycemia in pregnancy (HIP) is suggested to be a risk factor for elevated blood pressure (BP) in offspring. However, the empirical evidence was mixed. Thus, this systematic review and meta-analysis was conducted to synthesize current evidence assessing the association between HIP and BP in offspring.

Methods

We searched PubMed, MEDLINE, and Embase to identify articles published from inception until 9 February 2021. A random-effects meta-analysis was performed to calculate a pooled effect size and 95% confidence interval (CI). Furthermore, the effects were evaluated separately while grouping by the offspring’s sex, region, economic level, published year, insulin treatment status, and BP measurement. Each article was independently reviewed for quality.

Results

Of 3385 citations identified, 23 studies involving 88695 offspring were included. The study found that the offspring of women with HIP had an increased level of both systolic blood pressure (SBP; mean difference 1.90, 95% CI 1.09 to 2.70 mmHg, P < 0.001) and diastolic blood pressure (DBP; mean difference 0.87 mmHg, 95% CI 0.11 to 1.17 mmHg, P = 0.02) compared with those whose mothers with normal blood glucose during pregnancy. According to subgroup analyses, gestational diabetes mellitus (GDM) appeared to have varied impacts on offspring BP by sex of offspring, region and economic level of family, published year, maternal insulin treatment status, and BP measurement.

Conclusion

Current evidence showed that HIP was associated with an elevated BP in offspring. Prenatal interventions targated on reducing HIP might be beneficial for controlling for offspring BP.
Giant umbilical cord in a normal preterm infant: a case report and review of the literature
Authors: Hemmati Fariba , Barzegar Hamide , Oboodi Roya
Published: January 2023

Background

Giant umbilical cord, defined as a cord diameter of more than 5 cm, is an extremely rare malformation. There are few case reports of giant umbilical cord often associated with patent urachus duct or cystic malformation. These cases are usually managed by surgical excision and repair of patent urachus or cyst resection.

Case presentation

We report the case of a 1-day-old Iranian boy with giant umbilical cord detected postnatally. The pregnancy course was uneventful, except for preterm premature rupture of the membrane and preterm delivery. There was no relevant family history. The patient was delivered by vaginal delivery with a good Apgar score. On clinical examination, the umbilical cord was very thick (about 6 cm in diameter), and huge fluctuating Wharton’s jelly was observed. Other organs were normal. During the hospital stay, the patient did not develop any complications except borderline hyperbilirubinemia, which improved with conventional phototherapy. Since the umbilical cord had no discharge and was dried, the newborn was discharged with advice for cord drying care.

Conclusion

The newborn was well, and the dried umbilical stump was detached after 32 days, leaving a granulomatous structure without discharge. The patient was followed up for 4.5 months and had no problems except delayed separation of the umbilical cord.
Dynamic Response Analysis of Coastal Piled Bridge Pier Subjected to Current, Wave and Earthquake Actions with Different Structure Orientations
Authors: Alsultani Riyadh , Karim Ibtisam R. , Khassaf Saleh I.
Published: January 2023

The goal of the experiment described in this paper was to examine the effects of structure orientation (0°–90°) and fluid–structure interaction (FSI) under combined water loads, represented by water current and waves, and earthquake actions, on the dynamic response of a reduced-scale bridge pier specimen with pile foundation. The peak relative displacement and peak acceleration of the specimen are measured using the first time innovative in Iraq, Reality Water–Structure–Earthquake Interaction Test (RWSEIT). The findings are given and analyzed concerning water depths, current speed, wave characteristics, earthquake amplitudes, and structural orientations. A numerical model of the examined specimen with three dimensions (3D) was constructed, and the findings were successfully confirmed using the data from the experiments. A pile foundation bridge pier's 3D structural response under orientations that cannot be tested in a lab was computed using the constructed numerical model. The complicated dynamically produced FSI effects on the response of coastal pile foundation bridges may be better understood according to the research's experimental and numerical findings.
Development and performance of jacquard woven retro-reflective textiles with African design patterns
Authors: Seidu Raphael Kanyire , Choi Sun Young , Jiang Shouxiang
Published: January 2023

Retro-reflective materials are important for safety purposes, such as enhancing the visibility of pedestrians at night when they wear garments with reflective materials and therefore reducing pedestrian fatalities. This has challenged different manufacturers to produce effective materials that provide the best retro-reflection. Most of these materials are applied as stripes on clothing, but can also extend to artisans using reflective yarns in their creations. Nevertheless, there is a lack of research and the synthesis of reflective yarns and African design patterns (due to its symbolic value for the African people) to create effective textiles that have the necessary properties for visibility at night. In this research work, a new approach is adopted by using a design process that combines jacquard weaving technology, reflective threads and African design patterns to produce retro-reflective textiles. The subsequent reflective effects captured in a darkroom show the retro-reflective ability of the samples. The testing carried out by using the Kawabata Evaluation System for Fabrics shows that the total hand value (THV) of the samples makes them suitable for men’s winter dress shirts and women’s thin winter dresses (with positive values) but not suitable for the summer garment (with negative values) counterparts respectively. This new approach might extend the ideation to produce retro-reflective textiles that can be applied for many different uses.
Weighted-indexed semi-Markov model: calibration and application to financial modeling
Authors: De Blasis Riccardo
Published: January 2023

We address the calibration issues of the weighted-indexed semi-Markov chain (WISMC) model applied to high-frequency financial data. Specifically, we propose to automate the discretization of the price returns and the volatility index by using four different approaches, two based on statistical quantities, namely, the quantile and sigma discretization, and two derived by the application of two popular machine learning algorithms, namely the k-means and Gaussian mixture model (GMM). Moreover, by comparing the Bayesian information criterion (BIC) scores, the GMM approach allows for the selection of the number of states of returns and index. An application to Bitcoin prices at 1-min and 1-s intervals shows the validity and usefulness of the proposed discretization approaches. In particular, GMM discretization is well suited for high-frequency returns, whereas the quantile approach works better for low-frequency intervals. Finally, by comparing the results of the Monte Carlo simulation, we show that the WISMC model, applied with the proposed discretization, can reproduce the long-range serial correlation of the squared returns, which is typical of the financial markets and, in particular, the cryptocurrency market.
Predicting Fintech Innovation Adoption: the Mediator Role of Social Norms and Attitudes
Authors: Irimia-Diéguez A. , Velicia-Martín F. , Aguayo-Camacho M.
Published: January 2023

Digital innovation is challenging the traditional way of offering financial services to companies; the so-called Fintech phenomenon refers to startups that use the latest technologies to offer innovative financial services. Within the framework of the Theory of Planned Behavior (TPB) and the Theory of Reasoned Action (TRA), the primary purpose of this paper is to develop a causal-predictive analysis of the relationship between Subjective Norms, Attitudes, and Perceived Behavioral Control with the Intention to Use and Behavioral Use of the Fintech services by companies. Partial Least Squares Structural Equation Modeling methodology was used with data collected from a survey of 300 companies. Our findings support the TRA and TPB models and confirm their robustness in predicting companies’ intention and use of Fintech services. Financial technology innovators must understand the processes involved in users’ adoption to design sound strategies that increase the viability of their services. Studying the antecedents of behavioral intention to adopt Fintech services can greatly help understand the pace of adoption, allowing these players to attract and retain customers better. This study contributes to the literature by formulating and validating TPB to predict Fintech adoption, and its findings provide useful information for banks and Fintech companies and lead to an improvement in organizational performance management in formulating marketing strategies.