bluuebunny/crossref_metadata_2025 huggingface dataset:
NEPHROPROTECTIVE OF ETHANOL EXTRACT OF Annona muricata L. BARK ON PARACETAMOL-INDUCED NEPHROTOXICITY IN RATS
Authors: Sari Widya , Masykur Masykur , Adhilla Farah , Maisarah Rojatul , Fauziah Fauziah
Published: October 2023

Kidneys are organs that have the potential for damage caused by toxic substances. The use of paracetamol in high doses or long-term therapeutic doses can cause adverse effects in the form of damage to the kidneys. Plants that have the potential to become medicinal raw materials against kidney damage are Annona muricata L. The purpose of this study was to determine the potential protection of ethanolic extract of soursop bark (EESB) against histopathological rat kidney induced by toxic doses of paracetamol. This study used an experimental method using a completely randomized design (CRD). The normal control group (K0) and negative control (K-) were given distilled water, while in the treatment group the doses of EESB were 150, 300 and 600 mg/kgBW dissolved in 1 ml of distilled water for 14 days. On the 7th day, all groups of rats were given paracetamol at a dose of 1350 mg/kgBW except for the K0 group. Each group was 5 repetitions, so that in this study used 25 rats (Rattus norvegicus L.). Samples of kidney organs were taken on the 14th day to observe the histopathological structure of the tubular cells undergoing necrosis. The results showed that at a dose of 300 mg/kgBW EESB had the potential for protection against kidney histopathology by suppressing the occurrence of cell death (necrosis).Keywords: Soursop bark, kidney, paracetamol, necrosis
ORGANOLEPTIC TESTS OF PEMPEK WITH VARIOUS SURIMI FORMULATIONS OF SANGKURIANG CATFISH (Clarias gariepsinus)
Authors: Idealistuti Idealistuti , Suyatno Suyatno , Mutatauwi’ah Mutatauwi’ah , Sebayang Nico Syahputra
Published: October 2023

This study aims to study various surimi formulations of Sangkuriang catfish (Clarias gariepsinus) for the resulting pempek, using the experimental method using a Randomized Block Design (RBD) arranged in a non-factorial manner with one treatment of various formulations of surimi Sangkuriang catfish (Clarias gariepsinus) consisting of of six factors and repeated four times. Pempek organoleptic test results with hedonic tests on color, aroma, and taste. The highest preference value for the color of pempek made from sangkuriang catfish surimi in the L1 treatment (0.25 parts of sangkuriang catfish surimi and 1.00 parts of tapioca flour) with a clean white pempek color typical of fish pempek with an average value of 4.30 (criterion panelists liked). The highest preference value for the taste and aroma of pempek made from sangkuriang catfish surimi was found in treatment L6 (1.50 parts of sangkuriang catfish surimi and 1.00 parts of tapioca flour) with a savory taste and dominant pempek aroma with an average value of 3 .90 (panelists preferred criteria) and 4.30 (panelists preferred criteria).
ETHNOBOTANICAL STUDY OF BERANGAN (Castanopsis spp.) IN NAGAN RAYA DISTRICT INDONESIA
Authors: Phonna Rizza Amanda , Rasnovi Saida , Dahlan Dahlan , Arhas Firman Rija , Kusuma Hendrix Indra
Published: October 2023

Castanopsis spp., also known as berangan in Acehnese, is a chestnut species that is still used and well-known by the people of Indonesia. However, it is currently very rare and is becoming less well-known to today's younger generation. This research aims to study and understand how people in Nagan Raya process and use Castanopsis spp. species. Data were collected using two methods: ethnobotanical data and population data. The participatory rural appraisal (PRA) method was used in direct interviews to collect ethnobotanical data. Purposive sampling was used to obtain the Castanopsis spp. the population as much as local informants could show. There were 48 people from three groups of respondents who provided ethnobotanical data: traditional figures, farmers, and villagers who Castanopsis spp. species. The respondents in this study were divided into three groups based on their age, education, and occupation. There are 2 types of Castanopsis spp. that have been found in the Nagan Raya district, Castanopsis inermis and Castanopsis costata. They were discovered in forest areas, plantations, office/home yards, and roadside areas. Castanopsis spp fruits are commonly used as food, while the wood are usually used as carpentry/furniture wood and firewood. Kata Kunci: ethnobotany, berangan, chestnut, Castanopsis spp.
HERBAL SPECIES DIVERSITY IN PUTROE ALOEH TOURISM AREA, JEUMPA DISTRICT, SOUTHWEST ACEH REGENCY
Authors: Puspa Vivera Ruselli , Munawwarah Miftahul , Djufri Djufri , Wardiah Wardiah , Safrida Safrida , Muhibbuddin Muhibbuddin
Published: October 2023

The presence of vegetation in an area will positively impact the balance of the ecosystem on a broader scale. Herbs play an important role in maintaining vegetation conditions and cycling of plant growth in an area. The study aimed to determine the composition of vegetation, important values , and diversity index (Ĥ) of herbs in the Putroe Aloeh Tourism Area, Jeumpa District, and Southwest Aceh District. The method used is the observation method with the subjective determination of stations and plots using the quadratic method. Research stations as many as seven include; the downstreams left side of the river, the downstream right side of the river, the left middle side of the river, the middle right side, of the river the upstream left side of the river, the upstream right side of the river, and the surrounding forest. Each station is placed in 10 square plots measuring 2 x 2 m. Parameters observed include; absolute density (KM) of species, absolute frequency (FM) of species, and absolute dominance (DM) of species. Data analysis included the Important Value (IV) of species’ Important Value (IV) y Index (Ĥ). Based on the research results, it is known that there are 50 herb species consisting of 26 families. The dominating family is Asteraceae (20%). The species with the highest category of importance value was Selaginella doederleinii (IV = 48.48), while the species with the lowest category were Emilia sonchifolia and Cyperus strigosus (IV = 0.16). The diversity index of herbaceous species at the study site was medium (Ĥ= 2.43).
TWO-TIER MULTIPLE CHOICE (TTMC) INSTRUMENT FOR MEASURING STUDENTS' COMPLETE ABILITY QUESTION EVALUATED LEVEL (C5)
Authors: Taib Eva Nauli , Fazira Ika , Dewi Cut Ratna , Taib Evinopita
Published: October 2023

Data from the Program For International Student Assessment (PISA) explains that the weakness of Indonesian students is their inability when faced with problems that require skills, are critical, and creative. This study aims to describe students' ability to solve C5 questions, which is a cognitive level in solving HOTS (High Order Thinking Skills) questions using the Two-Tier Multiple Choice instrument. This type of research uses a quantitative approach with a descriptive method. The results showed that the answer categories of students who understood an average of 4.2%, students who misconceived an average of 13%, students who guessed an average of 26% and students who did not understand had an average of 56%, this figure shows that the average The highest average of students did not understand or could not solve well the questions with the cognitive level of evaluating or C5, so that it became a source of assessment for understanding student learning concepts, and could foster motivation in learning.
USING INTERACTIVE LECTORA INSPIRE SOFTWARE TO IMPROVE LEARNING OUTCOMES DURING PANDEMIC COVID-19
Authors: Toharudin Uus
Published: October 2023

One of the obstacles to the development of interactive learning media is the lack of mastery of interactive media development technology by teachers, so that the development of interactive learning materials with computers is not optimal. The purpose of this study was to test the effectiveness of interactive learning on motion system material assisted by the Lectora inspire software in improving learning outcomes. Using the pre-experimental method, this study involved 36 participants. Data collection techniques using test questions and questionnaires. Data analysis used the Wilcoxon test. The results of this study indicate that the effectiveness of using interactive Lectora Inspire software on motion material can improve student learning outcomes with a p-value of 0.006 where the p-value < α = 0.05. Thus the application of the Lectora Inspire software can be used as a solution, especially in online learning as a form of learning innovation.
DEVELOPMENT OF SMALL AND MEDIUM BUSINESS IN THE REGION: MANAGEMENT AND FINANCIAL TOOLS
Authors:   Central Russian Institute of Management, Branch of RANEPA, BOBROVA E.A. , SOTNIKOVA E.A. ,   Central Russian Institute of Management, Branch of RANEPA
Published: October 2023

In the context of increasing sanctions pressure, the destruction of traditional logistics and financial chains, exchange rate fluctuations and other manifestations of macroeconomic instability –this is not a complete list of external environmental factors that have had a negative impact on the development of small and medium Russian business in recent years. Therefore, the study of regional measures of state support for small and medium business seems to be an urgent scientific and practical task. The purpose of the study is to characterize the infrastructure for supporting small and medium business, to analyze the financial and managerial tools used for their development in the Orel region. Small and medium business acts as a driver of economic development in different countries of the world, playing a major role in providing employment, value chains, and the implementation of innovative business ideas. Results: based on the results of the study, the components of the support infrastructure, the main financial and management tools used at the regional management level for the development of small and medium business in the Orel region are characterized, a conclusion is made about the effectiveness of their functioning and the impact on the statistical indicators of the development of the studied segment of the regional economy. Recommendations are formulated regarding the optimization of the use of a program approach to managing the development of small and medium business in the region.
“Old Dolls Pulled out of the Wardrobe”, Stories by Marceline Desbordes-Valmore
Authors:   Lomonosov Moscow State University, Belavina Ekaterina M.
Published: October 2023

The prose tales of Marceline Desbordes-Valmore, a French writer of the Romantic era, represent an interesting stage in the evolution of the author’s fairy tale genre for children. Unlike magical fairy tales, there are no sorcerers, magical creatures or objects. On the one hand, these stories are reminiscent of moral parables and carry a certain lesson and morality, which was characteristic of the tales of the Enlightenment and the fable genre. On the other hand, they embodied the attention of the romantic era to the genre of autobiography. M. Desbordes-Valmore writes stories for her children that appear in the pages as heroes on a par with the writer herself: she portrays herself as a very young girl. These stories are based on events of their lives or memories of her childhood. The author uses real names and nicknames in her prose, but not directly, only using a variety of transfers. The dolls in M. Desbordes-Valmore’s fairy tale are primarily beautiful objects, but also “women in miniature”, a link in the chain of projections of “mother–daughter; daughter–doll” relationships. Some features of the descriptions and the accuracy of psychological observations allow us to say that in contrast with Balzac, Desbordes-Valmore avoids the fantastic. Desbordes-Valmore compares her tales with “old dolls pulled out of the wardrobe”. The image of the doll is important for her poetics, it can be found in shocking and intriguing titles (“Monster Dolls”, “Physiology of Dolls”), but contrary to the reader’s expectations, dolls do not come to life, and the only transformations and wonders revealed by M. Desbordes-Valmore are changes in the child’s soul and perception of the world.
Modern Pinocchios or the Artificial Human in Contemporary French Juvenile Literature: Philosophical, Ethical and Aesthetic Issues
Authors:   University of Rouen, Langbour Nadège
Published: October 2023

Pinocchio, the first and the most famous artificial character in children’s literature, was created by Carlo Collodi in 1881. The article analyzes the reasons for the character’s popularity in literature for children and youth, which appear to be found in the permanent development of the latter, both physical and psychological. At the same time, young readers to whom the text is addressed are also in the process of developing their self-identity. Based on analysis of the corpus of modern French novels for young people that involve hybrid beings (combining the properties of human beings and machines), the article explores intertextuality and philosophical foundations of the narrative (including the development of the concepts of “animal machines” by René Descartes and “human machines” by Julien Offray de La Mettrie), demonstrating a high didactic potential of such literature.
Creating Humans in Prometheus Myth in Fulgentius
Authors:   A.M. Gorky Institute of World Literature of the Russian Academy of Sciences, Protopopova Anna V. , Protopopov Ivan A. ,   Saint Petersburg State University of Aerospace Instrumentation
Published: October 2023

The article deals with the creation of a man from clay as an element of the Prometheus myth. This variation is clearly present in such early sources as Hesiod and Aesop, in classical antiquity — in Ovid and Properce; overall, it remains a rarity. In late antiquity it becomes more popular (Pausanias, Hygin, Lucian). Sometimes Prometheus is replaced by Hephaestus, sometimes it comes together with the Pandora myth, but the moment of bringing life to the clay figure is usually unclear. This mouth is so present in the “Mythologies” by Fulgentius (5–6 AD): his retelling of the myth as well as his interpretation are quite special. It is in fact a contamination of the previous versions (stealing fire and giving it to humans, ascent to heaven, creation of a man from clay, Athena’s helping out, Pandora, damnation for the stealing etc). The reason he stole the fire in “Mitologiae” is of particular interest: he aimed to bring life to the clay figure, not to help the mankind in its everyday life. The Fulgentian etymology of Prometheus’s name is analyzed along with the allegory of the kite. A special attention is paid to the philosophical meaning of the fire that brings a man to life.
Do Automatons Have a “Gender”? The Graft of Art and Science
Authors:   University of Pennsylvania, Met Philippe Charles
Published: October 2023

The present study examines the intersection of art and science, as well as gender ambiguity, crystallizing in the figure of the artificial creature, from two classic French examples variously adapted to the screen: “The Bloody Doll / The Assassination Machine” (1923/1924) by Gaston Leroux, a novel that became a television mini-series in 1976 thanks to Marcel Cravenne; and “The Hands of Orlac” (1920) by Maurice Renard, brought to the cinema in particular by Robert Wiene (“Orlacs Hände”, 1924) and Karl Freund (“Mad Love”, 1935). Verbal art reacts to scientific and technological progress, which has become the dogma of Enlightenment Europe, by highlighting the tragedy of scientific and technological creativity in culture. Literature and cinema show how the spirit creates monsters (killers, puppets, automatons), shifting the boundaries between the artificial and the natural, the imaginary and the rational. Science fiction transforms gender difference by fetishizing the gender ambiguity of the doll and recalling religious cultural stereotypes.
“The Rudelian Myth” in “The Story of a Barber Doll” by A.V. Chayanov (1918)
Authors:   Novosibirsk State Pedagogical University, Tyryshkina Elena V.
Published: October 2023

The paper is devoted to the functioning of the “Rudelian myth” in “The Story of a Barber Doll” by A.V. Chayanov (1918), which is realized through the transformed motives of “love for the doll” / “revitalization of the statue”. A journey in search of the “ideal sweetheart” in its classic legendary version is associated with the death of the protagonist, “distant love” is unattainable in principle. Vladimir M., falling in love with a doll in which he sees the embodiment of “perfect / final feminine”, takes a long journey, finds the girl who served as the model, one of the Siamese twins, they become lovers. The scenario of “ideal love” is ruined. The main conflict of the story relates to the tradition of the Gothic novel: seeking for inaccessible experience by mortal human being provides providence retribution. The story is a multivariate play with myths and literary traditions. As a result of the study, the author concludes: the well-known thesis of O. Freidenberg that “the idea of a doll is parallel with the idea of a deity-actor-corpse” is manifested in its classical triple unity in the neo-Gothic / decadent version: the world is a diabolical theater in which roles and masks alternate according to the law of perpetual iteration. The ideal love cannot be realized because deity turns into demon.
criatividade no novo contrato educativo para o século XXI
Authors: Miyata Edson Seiti , Maia Maria Vitória Campos Mamede
Published: October 2023

O objetivo do presente artigo é debater a educação para o século XXI por meio do diálogo entre a proposta de novo contrato educativo de Nóvoa (2009) e a criatividade. Inicia-se focalizando as pautas urgentes da educação para este século, ensejando a proposta do novo contrato educativo fundamentado em três premissas: educação como bem público, educação centrada na aprendizagem e no avanço do conhecimento e educação partilhada socialmente. Em seguida, discute-se a criatividade na educação, enfatizando o papel do pensamento divergente e flexível para fomentar uma educação mais dialógica e plural. Por fim, apresentam-se proposições elaboradas a partir do diálogo do novo contrato educativo com as contribuições da criatividade para o campo da educação. Conclui-se que a educação acolhedora, libertadora e partilhada precisará se apoiar na criatividade e na flexibilidade de pensamento, propiciando o avanço do conhecimento e abertura à pluralidade.
cenário da inclusão educacional a partir do encaminhamento escolar para identificação de altas habilidades/superdotação
Authors: Drulis Priscilla Basmage Lemos , Gomes Vera Lucia , Castro Rita de Fátima da Silva Rosas de
Published: October 2023

O presente artigo tem o objetivo de  analisar como acontece o encaminhamento para avaliação psicopedagógica dos estudantes com características de altas habilidades/superdotação matriculados nos 5º anos, das escolas estaduais de Campo Grande/MS. Como procedimentos metodológicos para coleta de dados utilizou-se a análise documental e dados do Projeto Piloto de Identificação de Estudantes com Altas Habilidades/Superdotação (AH/SD), desenvolvido pelo Centro Estadual de Atendimento Multidisciplinar para Altas Habilidades/Superdotação. Conclui-se que a inclusão escolar dos estudantes com altas habilidades está acontecendo de forma lenta e insignificante, visto o número de estudantes identificados e os que são encaminhados pelos professores do ensino regular para avaliação e identificação. Isso pode ter ocorrido ou pelo grande número de estudantes faltosos, ou pela falta de conhecimento dos professores sobre as diferentes características dos estudantes, o que não condiz com os princípios do direito educacional e da educação inclusiva, necessitando assim, de políticas públicas prioritárias isso ocorra.
Retratos contemplativos, experiência, memória e criação
Authors: Bittar Yuri , Liberman Flávia
Published: October 2023

O artigo aborda a relação entre imagem, memória e experiência, buscando compreender o potencial da prática da fotografia contemplativa na formação superior em saúde. Ao trazer a produção de retratos e histórias de vida criados na relação pesquisador-pesquisado, resultante de uma atividade realizada em uma disciplina eletiva em uma universidade pública em São Paulo, busca-se compreender as reverberações do curso e seus efeitos enquanto proposta formativa. Como referências teóricas centrais, o texto debate os conceitos de punctum, studium e biografema de Barthes, as condições e o valor da experiência em Larrosa Bondía e a importância da entrevista na cartografia em Tedesco. Buscamos ainda, ao final, construir uma reflexão sobre a potência interpelativa desta proposição no sentido de, para além de relatar acontecimentos, poder criar uma experiência humanizadora, sendo uma prática ao mesmo tempo contemplativa, criativa e formativa.
Global burden and cross-country inequalities in HCV-related liver diseases from 1990 to 2019
Authors: Bai Junzhu , Lv Hengliang , Zhang Leiliang , Wang Longhao , You Shumeng , Zhang Xin , Li Xuan , Wang Yong , Xu Yuanyong , Zhang Wenyi
Published: October 2023

Background & Aims: Acute hepatitis, cirrhosis and other
chronic liver diseases, and liver cancer caused by hepatitis C virus
(HCV) are have imposed a sever burden at the global. The study aims to
describe the burden and inequality analysis of HCV-related liver
diseases at the global. Methods: Our study utilized data from
the Global Burden of Diseases (GBD) 2019. Age-standardized rate of
incidence (ASIR), prevalence (ASPR), death (ASDR), and
disability-adjusted life years (DALYs) were employed to describe the
burden of HCV-related liver diseases across different populations and
regions worldwide. Additionally, we conducted an inequality analysis
using the slope index of inequality and concentration index to explore
the global disparities associated with HCV-related liver diseases
burden. Results: HCV-related diseases caused 542, 316 global
deaths in 2019. China (17% of total infections) and India (10% of
total infections) had the largest numbers of HCV-related disease, but
the ASPR was highest in Mongolia (9, 673.92 per 100, 000) and Cambodia
(5, 445.82 per 100, 000). The burden of Acute hepatitis C (AHC) was more
common in low socio-demographic index (SDI) regions, while HCV-related
liver cancer caused more large burden among the regions with higher SDI.
Conclusions: The burden of HCV-related liver diseases was still
at a relatively high level worldwide, and SDI was a significant factor
for differential distribution of the disease. Countries in the world
should take active parts in alleviating the burden of HCV-related liver
diseases, and take targeted measures according to their specific
circumstances.
Case report: Cardiac arrest after radiofrequency ablation in a 76-year-old male
Authors: Jin Geya , Li Shuyu , Pu Jianyi , Wang Yafeng
Published: October 2023

We report a 76-year-old male patient with persistent atrial fibrillation
(AF) who developed sinus arrest lasting 12 seconds in the early morning
of the forth day after using radiofrequency ablation for pulmonary vein
isolation. The patient had repeated episodes of sinus arrest after
implantation of a temporary pacemaker. After 3 weeks, the patient
stabilized and was discharged. The patient was followed up for 1 year
and did not experience any recurrence of sinus arrest or AF. We consider
the potential for postoperative myocardial edema, injury to the
sinoatrial node during the procedure, propafenone poisoning, and
autonomic dysfunction as contributors to the occurrence of sinus arrest
after radiofrequency ablation.
Using fish-based biological index to indicate eco-environmental status along the longitudinal gradient of a subtropical river
Authors: Wang Sai , Fan Shi-Di , Wu En-Ni , Xu De-Lin , Wang Tuan-Tuan , Wu Dong-Hai , Song Yong-Duo , Zhang Hong-Jin , Fu Guo-Ping , Chen Zhong-Bing , Guo Zhi-Qiang , Zhang Yang , Ma Zhuo-Luo
Published: October 2023

River ecosystems are facing a deepening biodiversity crisis. Developing
robust biotic indicators to assess ecological status across large
spatial scales are important. In the subtropical Liuxi River of southern
China, 34 fish indicators, including 4 genera and 30 species, were
selected from 108 fish species by linear discriminant analysis. These
indicators were combined into 18 groups and assigned scores according to
their species-specific requirements for food resources and habitat
patterns. The ecological and trophic functioning of optimized indicators
can reflect not only the community diversity and food web properties but
also the environmental quality of the ecosystem. Three formulas for
calculating the index of fish indicators ( IFI) were developed
based on the scoring of each indicator and weighted by relative
abundance (individual number, i.e., IFI) and
relative biomass (wet weight, i.e., IFI).
Spearman correlation analysis showed that IFI
exhibited a more powerful explanation of biodiversity and environmental
factors than IFI and unweighted IFI.
Therefore, we conclude that IFI has absolute
advantages in constructing an indicator-based environmental evaluation
system since it contains comprehensive information on biology and
ecology. In the future, the application of indicator scoring methods can
contribute greatly to the conservation and development of aquatic
ecosystems.
Prey density drives diet shift of the invasive mysid shrimp, Limnomysis benedeni
Authors: Rani Varsha , Horváth Zsófia , Nejstgaard Jens , Fierpasz Ádám , Pálffy Károly , Vad Csaba
Published: October 2023

Understanding the diet preferences and prey selection of invasive
species is crucial to better predict their impact on community structure
and ecosystem functioning. Limnomysis benedeni, a Ponto-Caspian invasive
mysid shrimp, is one of the most successful invaders in numerous
European river and lake ecosystems. While existing studies suggest
potentially strong trophic impact due to high predation pressure on
invaded plankton communities, little is known of its prey selectivity
between phyto- and zooplankton, under different prey concentrations.
Here, we therefore investigated the feeding selectivity of L. benedeni
on two commonly occurring prey organisms in freshwaters, the small
rotifer zooplankton Brachionus calyciflorus together with the
microphytoplankton Cryptomonas sp. present in increasing densities. Our
results demonstrated a clear shift in diet selection, with L. benedeni
switching from B. calyciflorus to Cryptomonas sp. already when the two
prey species were provided in equal biomasses. Different functional
responses were observed for each prey type, indicating somewhat
different foraging mechanisms for each prey type. These findings provide
experimental evidence on the feeding flexibility of invasive mysid
shrimps and potential implications for trophic interactions in invaded
ecosystems.
Characteristics, determinants, and frequency of persistent use among prescription opioid episodes initiated postpartum: a population-based cohort study from British Columbia, Canada
Authors: Schummers L. , Wilton James , Yu Amanda , Hutcheon Jennifer A. , Liauw Jessica , Pearce Margo , Chong Mei , Wong Stanley , Abdia Younathan , Purssell Roy , Z Naveed Janjua , A Jane Buxton
Published: October 2023

Objective: To determine the characteristics, determinants, and
persistent use for prescription opioid episodes initiated postpartum in
British Columbia (BC), Canada. Design: Population-based cohort,
2008-2015. Setting: Linked administrative databases including
outpatient and inpatient visits and outpatient prescription
dispensations for all individuals in BC tested for hepatitis C or HIV.
Population: Opioid-naïve individuals aged 13-49 with a delivery
hospitalization record. Methods: We used modified Poisson
regression to estimate risk ratios (RR) for pre-pregnancy
characteristics and adjusted RR (aRR) for delivery characteristics
adjusted for potential confounders. Main Outcome Measures: All
and persistent (≥90 days) prescription opioid episodes initiated
postpartum. Results: Among 292,684 eligible deliveries, 8.8%
(95% CI: 8.7% to 8.9%) initiated a postpartum prescription opioid
episode and 0.4% (0.4%- 0.5%) had a persistent episode. Persistent
prescription opioid episodes were more frequent among cesarean vs.
vaginal deliveries (1.0% vs. 0.2%, aRR 5.1 [4.6-5.8]). Opioid
episodes varied regionally and declined from 12.8% in 2008 to 7% in
2012-2015. Persistent prescription opioid episodes were associated with
pre-pregnancy: mental illness history (RR 2.4 [1.9-3.1]),
psychotropic medication use (RRs 3.6-4.9), chronic pain (RR 2.7
[1.8-3.9]) and alcohol misuse (4.6 [2.2-9.7]), and delivery
complications: intensive care unit admission (aRR 5.4 [3.3-8.9]),
postpartum hospital readmission (aRR 3.9 [3.2-4.8]), and vaginal
deliveries with hysterectomy (aRR 23.7 [6.1-91.8]) or tubal
ligation/salpingectomy (aRR 14.6 [5.4-39.4]). Conclusions:
Persistent prescription opioid episodes were initiated following 0.4%
of deliveries. Postpartum pain management strategies should consider the
strong associations between pre-pregnancy and delivery characteristics
and persistent prescription opioid episodes initiated postpartum.
Structural flexibility and heterogeneity of recombinant human glial fibrillary acidic protein (GFAP)
Authors: Gogishvili Dea , Illes-Toth Eva , J Matthew Harris , Hopley Christopher , E Charlotte Teunissen , Abeln Sanne
Published: October 2023

Glial fibrillary acidic protein (GFAP) is a promising biomarker for
brain and spinal cord disorders. Recent studies have highlighted the
differences in the reliability of GFAP measurements in different
biological matrices. The reason for these discrepancies is poorly
understood as our knowledge of the protein’s 3-dimensional conformation,
proteoforms, and aggregation remains limited. Here, we investigate the
structural properties of GFAP under different conditions. For this, we
characterised recombinant GFAP proteins from various suppliers and
applied hydrogen-deuterium exchange mass spectrometry (HDX-MS) to
provide a snapshot of the conformational dynamics of GFAP in artificial
CSF compared to the phosphate buffer. Our findings indicate that
recombinant GFAP exists in various conformational species. Furthermore,
we show that GFAP dimers remained intact under denaturing conditions.
HDX-MS experiments show an overall decrease in H-bonding and an increase
in solvent accessibility of GFAP in aCSF compared to the phosphate
buffer, with clear indications of mixed EX2 and EX1 kinetics. To
understand possible structural interface regions and the evolutionary
conservation profiles, we combined HDX-MS results with the predicted
GFAP-dimer structure by AlphaFold-Multimer. We found that deprotected
regions with high structural flexibility in artificial CSF overlap with
predicted conserved dimeric interface regions. Our results suggest that
GFAP exists in several conformational forms. Structural property
predictions combined with the HDX data show an overall deprotection and
signatures of aggregation in aCSF. We anticipate that the outcomes of
this research will contribute to a deeper understanding of the
structural flexibility of GFAP and ultimately shed light on its
behaviour in different biological matrices.
The Identities of Employed Students: Striving to Reduce Distinctiveness from the Typical Student
Authors: Grozev Vladislav , Easterbrook Matthew
Published: October 2023

Endorsement of the employed student identity can provide social support
for employed students or protection from negative intergroup
comparisons. However, not much is known about what identity aspects or
characteristics comprise the employed student identity and how they
become important and central to that identity. Using data from 215
employed university students in the UK, we investigated two research
questions (RQ’s) in this mixed-method study. RQ1. What are the identity
aspects that participants ascribe to the employed student identity? RQ2.
Are identity aspects that distinguish employed from non-employed
students, and are considered more suitable for employed versus
non-employed students, more central and more important to the employed
students’ self-concept? A thematic analysis categorised the identity
aspects that participants selected into 14 distinct categories, with the
most important categories being hard-working, being organised, having
motivation, and discipline. Multilevel analyses of identity aspects
within individuals revealed that distinctiveness was negatively
associated with the importance and centrality of aspects, whereas
suitability for employed students was positively associated with the
importance and centrality of aspects. We offer practical value through
revealing important identity aspects which inoculate employed students
against negative intergroup comparisons, and theoretical value through
suggesting future avenues for employed students’ identity construction.
Teste
Authors: Xavier Adriana
Published: October 2023

ff
Impact of chemical reaction, viscous dissipation and thermal radiation on MHD flow past an oscillating plate
Authors: Rajaraman Rengasamy , Muthucumaraswamy Rajamanickam
Published: October 2023

This study analyzes the consequences of first-order chemical reactions, radiation, and viscous dissipation on the unsteady magnetohydrodynamic natural convective flow of a viscous incompressible fluid over a vertically positioned semi-boundless oscillating plate with uniform mass diffusion and temperature. An implicit finite-difference technique is employed to solve a set of dimensionless, coupled, nonlinear partial differential equations. The numerical results for fluid velocity, concentration, and temperature at the plate under different dimensionless parameters are graphically displayed. Due to first-order homogeneous chemical reactions, it has been discovered that the velocity rises at the time of a generative reaction and drops during a destructive reaction. A decline in velocity is observed with an increase in the phase angle, radiation parameter, and chemical reaction parameter. Further, it has been revealed that plate oscillation, radiation, chemical reactions, and the magnetic field significantly influence the flow behavior.
An EPQ model for delay deteriorating products with price, freshness and greening efforts dependent demand under markdown strategy
Authors: Katariya Dharmesh , Shukla Kunal
Published: October 2023

Consumers today use green, fresh, perishable products because of their freshness, healthfulness, and sustainability. In this article, we developed the continuous production inventory model for the producer who produces and sells fresh perishable products with the input of green efforts. There are two distinct kinds of product decay to take into account: products whose physical condition gradually deteriorates over time at a constant rate, and products whose freshness quality declines with time. Product demand is influenced by the selling price of the product, its freshness level, and its greening efforts. In order to increase the sales of inventory and enhance the profit from clearing stocks at the end of their life, we have adopted the markdown policy. Due to freshness degradation, a markdown strategy is adopted after a period of product deterioration to boost demand. The objectives of the study are to find out the optimal period for replenishment cycle time, the optimal value of greening efforts, and the optimal markdown percentage such that the producer?s total profit is maximum. A numerical example is used to validate a mathematical formulation that reflects real-world circumstances. A sensitivity analysis of the parameters is done to determine the model's reliability. Some significant managerial results are provided, and the article concludes with a consideration of the future scope of related research.
Orkestrert læring og global kulturbygging
Authors: Hekneby Torbjørn , Ingvaldsen Jonas A. , Benders Jos , Jenssen Jan Inge , Lehland Katja
Published: October 2023

Formålet med denne artikkelen er å synliggjøre hvordan Elkem utviklet, innførte og distribuerte sitt program for prosessforbedring, Elkem Business System (EBS). Over 15 år utviklet bedriften programmet gjennom utprøving av ulike organisasjonskonsepter. Konseptene ble ikke brukt som beste praksis, men som inspirasjon til eksperimentering og læring. Toppleders rolle var det vi kaller å orkestrere læring. Den består av å inspirere til lokale eksperimenter, å konsolidere lærdommene i et felles, overordnet produksjonssystem samt å sikre institusjonalisering av systemet. Elkem distribuerte sitt forbedringsprogram internasjonalt ved å bygge en sterk internkultur. Dette ble gjort ved å utfordre grunnleggende antakelser på alle nivåer i selskapet knyttet til kontinuerlig forbedring og ansattes medvirkning. Våre funn har vesentlige praktiske implikasjoner for ledere som ønsker å sette kontinuerlig forbedringsarbeid i system og ikke minst lykkes med å skape engasjement for dette på alle nivåer i organisasjonen.
Four Questions to Guide Decision-Making for Data Sharing and Integration
Authors: Hawn Nelson Amy , Zanti Sharon
Published: October 2023

IntroductionThis paper presents a Four Question Framework to guide data integration partners in building a strong governance and legal foundation to support ethical data use.
ObjectivesWhile this framework was developed based on work in the United States that routinely integrates public data, it is meant to be a simple, digestible tool that can be adapted to any context.
MethodsThe framework was developed through a series of public deliberation workgroups and 15 years of field experience working with a diversity of data integration efforts across the United States.
ResultsThe Four Questions - Is this legal? Is this ethical? Is this a good idea? How do we know (and who decides)? - should be considered within an established data governance framework and alongside core partners to determine whether and how to move forward when building an Integrated Data System (IDS) and also at each stage of a specific data project. We discuss these questions in depth, with a particular focus on the role of governance in establishing legal and ethical data use. In addition, we provide example data governance structures from two IDS sites and hypothetical scenarios that illustrate key considerations for the Four Question Framework.
ConclusionsA robust governance process is essential for determining whether data sharing and integration is legal, ethical, and a good idea within the local context. This process is iterative and as relational as it is technical, which means authentic collaboration across partners should be prioritized at each stage of a data use project. The Four Questions serve as a guide for determining whether to undertake data sharing and integration and should be regularly revisited throughout the life of a project.
Highlights

Strong data governance has five qualities: it is purpose-, value-, and principle-driven; strategically located; collaborative; iterative; and transparent.
Through a series of public deliberation workgroups and 15 years of field experience, we developed a Four Question Framework to determine whether and how to move forward with building an IDS and at each stage of a data sharing and integration project.
The Four Questions—Is this legal? Is this ethical? Is this a good idea? How do we know (and who decides)? —should be carefully considered within established data governance processes and among core partners.
MAMPUKAH STRUKTUR MODAL MEMEDIASI PENGARUH CEO NARCISSISM DAN OVERCONFIDENCE TERHADAP KINERJA PERUSAHAAN?
Authors: Candy Candy , Delfina Delfina
Published: October 2023

CEOs in corporations may not always employ logical reasoning when making decisions and may be swayed by personal characteristics such as overconfidence and narcissism. The decisions made by CEOs ultimately affect the company's performance. This study examines how CEO overconfidence and narcissism affect firm performance in the presence of capital structure variables. The study surveyed 39 infrastructure companies listed on the Indonesia Stock Exchange between 2017 and 2021, totaling 175 observations. The data were analyzed using Stata 16 to test the direct effect, and indirect effects were tested using the Sobel test. Results indicate that neither CEO overconfidence nor narcissism has a significant impact on a firm's performance, as measured by ROA or ROE. Furthermore, CEO narcissism has no impact on firm performance mediated by capital structure, while capital structure can mediate the effect of CEO overconfidence on ROA but not on ROE
PENCEGAHAN FRAUD DENGAN FRAUD CONTROL PLAN: KASUS PADA MANAJEMEN RUMAH SAKIT BLUD DI INDONESIA
Authors: Suhendro Saring , Sembiring Sari Indah Oktanti
Published: October 2023

Internal Control is expected to be able to prevent and detect fraud. The Indonesian government uses the Government Internal Control System (SPIP). Management's understanding of SPIP is crucial to ensuring adequate SPIP is implemented in BLUDs. After SPIP is the Fraud Control Plan, both developed by BPKP and are expected to be able to carry out fraud deterrence in BLUD hospitals in Indonesia. According to IcekAjzen's theory of planned conduct, dishonesty has roots in the individual's psyche and goals. This research seeks to verify that hospital BLUD management understands SPIP management, has positive attitudes about behavior, has subjective standards, perceives that they influence their conduct, and intends to utilize FCP to avoid fraud. Indicators of fraud deterrence and FCP as new ideas are presented in this research. The study was conducted on management working in several BLUD hospitals in Indonesia. The results show that management's fraud prevention actions are based on its intention to implement a Fraud Control Plan.
PENGARUH KOMPETENSI DAN TEKANAN FINANSIAL TERHADAP KECENDERUNGAN KECURANGAN LAPORAN KEUANGAN
Authors: Oktavia Reni , Alvia Liza , Octary Ayu Dwiny
Published: October 2023

Fraud atau kecurangan adalah tindakan dan menipu guna memperoleh keuntungan pribadi. Fraud dalam laporan keuangan merupakan masalah dalam organisasi yang menurunkan kepercayaan pihak yang berkepentingan seperti pemilik perusahaan atau calon investor terhadap keandalan dan objektivitas laporan keuangan. Penelitian ini memiliki tujuan untuk mengetahui apakah kompetensi dan tekanan finansial berpengaruh terhadap kecenderungan terjadinya kecurangan laporan keuangan. Variabel independen penelitan ini adalah kompetensi yang diproksikan oleh pergantian serta tekanan finansial yang diproksikan oleh nilai Return on Assets, sedangkan variabel dependen penelitian ini adalah kecurangan laporan keuangan yang diukur menggunakan Dechow F-Score. Populasi penelitian ini adalah perusahaan BUMN Non-Keuangan yang terdaftar di BEI dengan 91 sampel penelitian. Data penelitian ini diolah dengan analisis regresi logistik menggunakan aplikasi IBM SPSS 26. Penelitian ini diharapkan dapat memberikan kontribusi sebagai saran dan masukan kepada pemerintah dan perusahaan agar dapat mencegah terjadinya kecurangan laporan keuangan.
PENGARUH KEPEMILIKAN ASING DAN FAKTOR LAINNYA TERHADAP PENGUNGKAPAN TANGGUNG JAWAB SOSIAL
Authors: Mulansari Isna , Harsanti Ponny , Delima Zamrud Mirah
Published: October 2023

This study aims to examine the effect of foreign ownership,institutional ownership, leverage, and the size of the board ofdirectors on the disclosure of corporate social responsibility.The population used is mining companies listed on the IndonesiaStock Exchange (IDX) for 2016-2020 with a sample that has beenselected using the purposive sampling method. The total sampleanalyzed was 61 companies using multiple linear regressionanalysis with the help of SPSS 25. The results showed that the sizeof the board of directors has a positive effect on the disclosure ofcorporate social responsibility. Foreign ownership, institutionalownership, and leverage have no effect on the disclosure ofcorporate social responsibility.
A LoRaWAN-based IoT System for Leakage Detection in Pipelines
Authors: Agbolade Olaide , Olanrewaju Oyindamola , Oyetunji Samson , Babatola Josiah
Published: October 2023

Leakages in a pipeline are an important problem due to the potential economic and environmental hazard they present. In this study, we proposed a LoRaWAN-based approach for detecting and localizing leakages in pipelines. Our study includes an experimental setup that simulates a pipeline network with pressure and flow rate sensors attached. The flow rate and pressure data were transmitted through LoRaWAN to a receiver, which in turn uploads the data to a cloud server using a cellular network. The receiver compares the flow rate reading from all the monitoring nodes attached to the pipeline network. If flow rate reading from successive nodes presents a percentage variation of more than 1.5%, a leak is confirmed to have taken place. The flow rate readings can also be used to localize the leak. The resolution of the leak detection is dependent on the number of monitoring nodes on the pipeline network. In our study, the pressure readings were found to be insufficient to provide reliable evidence of leakages. In our specific situation, due to the relatively short length of the experimental pipeline network, a pressure drop of up to 38.2% was recorded between successive nodes with an overall pressure loss of 62%, making pressure data unsuitable for leak detection in the short pipeline network.
Optimal Energy Management System Control of Permanent Magnet Direct Drive Linear Generator for Grid-Connected FC-Battery-Wave Energy Conversion
Authors: Elgammal Adel , Boodoo Curtis
Published: October 2023

The Wave Energy Conversion System (WECS) control strategy is presented in this study to make sure the system operates at its best under fluctuating wave resource situations. The suggested system consists of a MOPSO based MPC approach, a point absorber WEC oscillating in heave, back-to-back power converter for grid connections, and a linear permanent magnet generator. Despite the benefits of model predictive control, problems including switching frequency variations, steady-state errors, high processing costs, and constrained prediction horizons continue to exist. The article presents a method that incorporates the switching control action into the cost function while maintaining the finite nature of a model predictive control to handle the switching frequency issue. In order to minimise switching frequency variations while also addressing other control goals, such as regulating the direct current linked voltage and controlling the flow of active and reactive power, the switching control weight factors are optimised. In order to increase power quality, a fuel cell-based short-term energy storage system is also included to direct current link between the back-to-back converters.
Coronavirus and the Rise of Child Witchcraft Accusations
Authors: Dein Simon
Published: October 2023

This paper examines the impact of witchcraft accusations with a focus on Africa and children. After presenting an overview of anthropological understandings of witchcraft in Africa, it focuses on increasing allegations of witchcraft among children. It discusses how this phenomenon may occur in the UK and its implications for social workers and police. Faith based child abuse is becoming more common in the UK and the COVID pandemic is a major risk factor for this.