bluuebunny/crossref_metadata_2025 huggingface dataset:
Establishing patterns in the structure formation of polymer nanocomposites based on polyamide 6 during their crystallization processes
Authors: Fialko Nataliia , Meranova Nataliia , Sherenkovskii Julii , Navrodska Raisa , Babak Vitalii , Korzhyk Volodymyr , Lazarenko Maxim , Koseva Neli , Konoreva Oksana , Dinzhos Roman
Published: July 2024

This paper reports experimental and computational studies on patterns in the structure formation of polymer nanocomposites when different types of fillers are used. The study was conducted for nanocomposites based on polyamide 6 filled with carbon nanotubes or silicon dioxide nanoparticles. In the course of research, the mass fraction of the filler varied from 0.2 % to 4.0 %, and the cooling rate of the melt composite varied from 0.5 K/min up to 20 K/min.
Data on experimental and theoretical studies into the mechanisms of structure formation of composites according to the method, which includes two stages, are given. According to the first stage, crystallization exotherms of nanocomposites were experimentally obtained when they are cooled from the melt at a given constant rate. The dependence of various characteristics of the crystallization process on the mass fraction of the filler and the cooling rate of the composite was established.
At the second stage, based on the analysis of the obtained crystallization exotherms, theoretical studies were performed to determine the mechanisms of structure formation of nanocomposites at different stages of crystallization. For the initial stage, according to the nucleation equation, the presence of two mechanisms of structure formation – planar and volumetric – has been shown.
Within the framework of the Kolmogorov-Avrami equation, the mechanisms of structure formation at the next stage of crystallization were established, which corresponds to the formation of ordered structures in the material within the volume of the polymer composite as a whole. The research was carried out assuming the existence of a mechanism of crystallization of the polymer matrix itself, which is realized on fluctuations in the density of the polymer, and a mechanism of crystallization, the centers of which are filler particles.
The use of the proposed nanocomposites is promising for the manufacture of parts of energy equipment, electronic equipment, elements of chemical, processing, defense industry installations, etc.
Development of predictive model for determination of paraffin deposition in Kazakh crude oil
Authors: Sarsenova Adel , Ismailova Jamilyam , Ismailov Abdulakhat , Delikesheva Dinara , Kaidar Aigerim
Published: July 2024

Kazakhstan's crude oil contains significant amounts of heavy hydrocarbons that solidify as wax at lower temperatures, leading to reduced flow rates and potential blockages in pipelines. Paraffin, a substantial component of crude oil, crystallizes below its pour point, posing challenges for maintaining efficient crude oil transportation. Addressing wax deposition is essential for optimizing oil flow and meeting global energy demand. This article presents an innovative method for forecasting paraffin deposition in Kazakh crude oil, using its chemical composition and thermobaric conditions. The methodology encompassed data analysis, ASTM-standard laboratory tests, and computations employing modified equations for fusion properties calculation. Outcomes comprise computed temperatures, enthalpy, and heat capacity related to melting, along with revised correlations for melting and pour points specific to Kazakh crude oils. The melting point correlation was modified to fit the properties of Kazakh crude oils, resulting in standard deviation of 0.55 %. Computed pour points for hydrocarbons improved by 17 % respectively. As a result of the research a novel software tool was developed and evaluated, highlighting the project’s contribution in providing an adjusted thermodynamic model for paraffin deposition forecasting. Comparisons between the developed software, PVTSim, and field data showed the wax appearance temperature (WAT) predictions closely aligned, with 0.74 % of error. This numerical tool shows potential in predicting wax deposition, thus aiding in the planning of oil production and refining processes in Kazakhstan. The importance of this work extends to its potential economic impact on companies and the nation, as well as its environmental benefits by facilitating eco-friendly planning of oil production facilities. Future research could expand on these findings to further enhance predictive models of paraffin precipitation across diverse conditions
Improving safety criteria for transporting hazardous goods by road through optimizing the geometric parameters of their stowage
Authors: Pustiulha Serhii , Samchuk Volodymyr , Prydiuk Valentyn , Pasichnyk Oksana , Shymchuk Oleksandr
Published: July 2024

The object of research is the process of cargo transportation by road. The problem of efficient loading and securing of hazardous goods in box containers during their transportation by road is considered.
The basic principles of the voxel-based interpretation of the model of loading box containers on road transport are presented, and a general principle for calculating the fractal dimension of such three-dimensional objects has been developed. The calculation is based on the procedure of reducing the dimensionality of space by cutting the object into separate layers and determining the fractal dimensionality of two-dimensional slices. The proposed principle could be used to estimate the fractal dimension of three-dimensional objects in practical tasks in any industry.
A method for simplified calculation of fractal characteristics of three-dimensional bill of lading models of cargo stowage has been devised. The method is based on the assessment of the quality of blocking of the constituent elements of the spatial system in three coordinate directions by the fractal dimension of two-dimensional images of their frames. The method provides opportunities for calculating the quantitative characteristics of the quality of cargo stowage from the standpoint of its transportation safety.
A method for fractal stowing of goods in box containers on a truck platform has been proposed. This method of fractal stowage provides for the absence of slippage and displacement of boxes in the package and makes it impossible for them to overturn in extreme situations. The use of the fractal stowage method allows for an efficient and low-cost technology of securing the cargo as it involves only a circular bandage of the top layer of the loaded package of boxes and its fastening to the vehicle platform at four points
Pharmacological and technological studies in the development of tablet composition with acorus calamus leaf extract
Authors: Andryushayev Oleksiy , Samoilov Yevhenii , Hnatiuk Valeriia , Ruban Olena , Velia Mariia , Savokhina Maryna
Published: July 2024

The aim: To determine the optimal qualitative and quantitative composition of auxiliary substances for tablets containing dry extract of Acorus calamus leaves and the solid dispersion of quercetin, their relatively therapeutic dose and antiexudative activity.
Materials and methods: This study determined a relatively therapeutic dose of dry extract of Acorus calamus leaves, investigated the impact of various auxiliary substances on the properties of tablets formulated with active ingredients - dry extract of Acorus calamus leaves and solid dispersion of quercetin, and assessed antiexudative activity these tablets. The comprehensive analysis entailed the utilization of standardized pharmacopoeial methods to evaluate the quality of the tablet samples. These methods encompassed a range of assessments designed to ensure that the tablets met the requisite pharmacological standards, focusing on key characteristics such as dissolution rate and stability. Determination of the relatively therapeutic dose and antiexudative activity made using standard pharmacological methods in laboratory rats.
Results: In-depth exploration during the study led to identifying Ac-Di-Sol and Lubripharm SSF as the most suitable auxiliary substances for the tablet composition. Detailed analysis revealed that Ac-Di-Sol, when utilized at a 10 % concentration, markedly improved the tablets' disintegration rate without adversely affecting their structural integrity. Concurrently, Lubripharm SSF was observed to significantly enhance the tablets' mechanical stability by reducing their friability.
Conclusions: As a result of the study, the relatively therapeutic dose of dry extract of Acorus calamus leaves, and the solid dispersion of quercetin, optimal auxiliary substances for the tablet formulation - Ac-Di-Sol and Lubripharm SSF - were established. The conducted research enabled the development of a tablet composition that aligns with the requisite pharmacotechnological specifications and conditions of the modern pharmaceutical industry and demonstrates high antiexudative activity relative to monocomponent substances and famous drugs
Comparative pharmacognostic study of the roots of the most common species of plants of the genus arctium
Authors: Oproshanska Tetiana , Khvorost Olga , Skrebtsova Kateryna , Savchenko Lesia , Fizor Natalya
Published: July 2024

The aim is to carry out a comparative pharmacognostic study of the roots of A. tomentosum and A. minus with the root of A. lappa to confirm or deny their interchangeability.
Materials and methods. A Delta optic BioLight 300 microscope (Poland) was used to study the macro- and microscopic features of plant raw materials. The method of gas chromatography-mass spectrometry was used to identify and quantify organic, including fatty, acids. Quantitative content of amount of organic acids, ascorbic acid, total polyphenols and amount of hydroxycinnamic acids was determined by using spectrophotometry. The content of polysaccharides was determined by the gravimetric method.
The results. For the first time, a comparative morphological and anatomical study of the roots of A. tomentosum and A. minus in comparison with the root of A. lappa was carried out. As a result, a distinctive diagnostic microscopic feature of the roots was established: the shape of the receptacles of the schizogen type. For the first time, the component composition of organic, including fatty acids, for the roots of A. tomentosum and A. minus was determined in comparison with the root of A. lappa, which is the same. The content of 11 organics and 12 fatty acids in plant raw materials of 3 Arctium species was identified and determined. The quantitative content of the amount of organic acids, ascorbic acid, polysaccharides, total polyphenols, and amount of hydroxycinnamic acids in the roots of A. tomentosum and A. minus in comparison with the root of A. Lappa was established, and these indicators are comparable.
Conclusions. For the first time, a comparative pharmacognostical study of the roots of A. tomentosum and A. minus in comparison with the root of A. lappa was carried out which showed minor differences between the roots of these Arctium species and confirms their interchangeability at this stage, especially when harvesting wild plant raw materials, when identification of the species at the botanical level is impossible
Novel eco-friendly spectrophotometric determination of lercanidipine hydrochloride in tablets using methyl red
Authors: Kryskiw Liubomyr , Horyn Mariana , Kucher Tetyana , Zarivna Nadiya , Poliak Olha , Logoyda Liliya
Published: July 2024

The aim of the work was to develop a simple, eco-friendly, quick, affordable and alternative spectrophotometric procedure that uses the azodye methyl red (MR) for the determination of lercanidipine in its dosage form considering the “green” chemistry principles.
Materials and methods. Analytical equipment: Shimadzu UV-1800 double beam UV-visible spectrophotometer (Japan) with included UV-Probe 2.70 software, RAD WAG AS 200/C precise analytical balance (Poland), Elmasonic EASY 40H ultrasonic bath.
Lercanidipine hydrochloride (purity 99 %) was purchased from Jiyan Chemicals (India). Lercanidipine tablets 10 mg and 20 mg were used in our experiments.
Results and discussion. To determine the amount of lercanidipine in tablets, a spectrophotometric method has been developed. To select the best dye for the method development, we tested a variety of dyes, including MR, bromocresol purple, bromophenol blue, cresol red, bromocresol green and bromothymol blue. We selected MR as the reagent based on the experimental studies' outcomes, and the solvent was an acetonitrile and ethanol mixture with a ratio of 95 to 5. The optimal parameters were determined for the quantitation of lercanidipine in tablets utilizing MR with 5×10-5 mol/L of dye concentration, 0.5 ml of MR solution, at a temperature of 25 °C without heating; detection wavelength was 498 nm and reaction time of 5 min. By using the molar ratios (saturation) method and Job's (continuous variations) approach, the stoichiometric coefficients of reacting components involving lercanidipine and dye were established to be 1:1. The proposed spectrophotometric procedure was linear within the concentration ranging from 6.48 – 32.41 μg/mL. Using the least squares method, a regression equation was generated: y = 0.0208x – 0.0318. The correlation coefficient was higher than 0.999, indicating that the analytical procedures' linearity is acceptable; the limit of detection and limit of quantitation were 1.19 μg/mL and 3.62 μg/mL, respectively. The robustness, accuracy and precision of the study results fell within acceptable limits. The proposed method was successfully applied to determine the content of lercanidipine in its tablet dosage forms. The analysis of the method's "greenness" using AGREE and GAPI tools yielded excellent results.
Conclusions. The method that has been developed can serve as an alternative approach for the routine control of lercanidipine content in its tablets
Towards gender equality: women’s leadership in higher education
Authors: Khraban Tetiana , Vyhivska Oksana
Published: July 2024

This article aims to provide a systematic review of the scientific literature on women’s leadership in higher education. This study was conducted in April 2024. It was based on scientific articles, selected from the Academia.edu portal. The study employed a non-experimental research design. The representation of women in management and leadership positions in the higher education sector has increased significantly, yet this growth has been limited to academic roles with the requisite authority to teach. Management positions with greater responsibility have not seen the same level of advancement. The prevailing masculine culture that pervades higher education presents an impediment to women's advancement to senior management roles. This is attributable to a confluence of interrelated factors, including structural constraints, competitive job demands, demanding work schedules, and the necessity to balance work and family life. The situation is further complicated by the introduction of accountability measures and sophisticated evaluation instruments, designed to assess and accredit work processes, hyper-productivity, and continuous evaluation. Despite the growing focus on gender issues, the prevalence and intensity of negative gender stereotypes about women appear to be on the rise. The negative dynamics, observed in sociological surveys, can be explained by examining the current state of gender ideology, education, and public awareness within society. The observed trends in economic activity, employment status, and salaries of men and women do not appear to be driving significant changes in gender stereotypes or the socioeconomic status of women. In light of these considerations, it becomes imperative to examine the necessity of implementing a feminist approach to appointing managers and leaders within higher education institutions. It is important to acknowledge that the roles, duties, and responsibilities of leaders within higher education institutions may differ considerably. It can be reasonably argued that the styles of leadership, employed by male and female higher education managers and leaders, exert a profound influence over the nature of organizational cultures. It is of the utmost importance that each higher education institution conducts an assessment of its own to ascertain its current situation and the manner, in which its managers and leaders contribute to the overall organizational success. It is recommended that institutions of higher education implement policies that consider gender aspects, with the aim of enhancing the utilization of women’s potential for leadership. It is imperative to implement a gender-based assessment mechanism to ensure equitable competition between women and men in the selection process for managerial and leadership roles
Media educational approach to forming information literacy of lyceum students in Ukrainian language lessons
Authors: Bainyashova Svitlana
Published: July 2024

The article describes one of the current educational problems - the formation of information literacy of students in the process of learning the Ukrainian language based on the media education approach. The approach to learning was considered as a basic category that determines the further direction of learning the native language and the choice of the method of its implementation in further school practice. The article specifies the definition of "information literacy". The task of media education for the educational process is defined. The importance of using media texts in the educational process was emphasized. The goals, set for information literacy, are indicated. Theoretical research methods were used, which helped to more thoroughly investigate the aspects of the media educational approach to the formation of information literacy of a young language personality. Within the framework of the media education approach, the types of educational works are described. The general trends of modern times in the aspect of development and integrated implementation of the media approach to the subject of school education, which positively affects the content of education, are taken into account. The vector of this research is focused on the works of Ukrainian scientists. The peculiarities of studying the Ukrainian language on the basis of the media education approach are characterized. The principles of the formation of information literacy of students in the process of learning the Ukrainian language are outlined, which can ensure effective interaction of high school students with the modern media system and information resources. A number of works by foreign researchers were analyzed in order to describe how to correctly implement the media education process in Ukrainian language classes. There are several methods that should be used within the media education approach. It is taken into account that the ability to use various technologies and media means in the educational process is a significant advantage and progress in pedagogical activity. The importance of the development of the teachers themselves in the direction of technology is emphasized
Stroke death rates among adults ages 45-64 by region and race and Hispanic origin: United States, 2002-2022
Authors: Curtin, C Sally
Published: July 2024

This report provides health data from the National Center for Health Statistics.
Colonización y poblamiento en Antioquia (Colombia), 1850-1890. Los casos de Titiribí, Concordia y Jericó
Authors: Ramirez Bacca Renzo , Londoño-Uriza Elidio Alexander
Published: July 2024

El propósito del artículo es analizar el proceso de colonización, poblamiento y producción en las localidades de Titiribí, Concordia y Jericó entre 1850 y 1890. El estudio considera las dinámicas de asentamiento y examina las modalidades de configuración poblacional y económica de las tres localidades. Los casos seleccionados revelan tanto formas de poblamiento espontáneo como empresarial, particularmente respaldadas por la explotación minera y agropecuaria. Esta aproximación histórica busca ofrecer un análisis procesal, proponiendo una perspectiva de estudio de caso tomando en consideración tanto la historiografía regional como los archivos locales disponibles.
Víctor Manuel Moncayo y Hernán Darío Correa. Rebelión universitaria 1971-1972. Una búsqueda de ruptura (Memoria a propósito del cogobierno en la Universidad Nacional). Bogotá: Universidad Nacional de Colombia, 2023.
Authors: Acevedo Tarazona Álvaro , Agudelo Castañeda Natalia
Published: July 2024

El libro “Rebelión Universitaria 1971-1972: Una Búsqueda de Ruptura" fue publicado en 2023 por la Universidad Nacional de Colombia. Este documento se presenta como una lectura crucial en el contexto de la reforma anunciada a la educación colombiana, particularmente en la educación superior. En este momento también es notoria la reactivación de la movilización estudiantil, la cual recientemente ha unido fuerzas a través del Encuentro Nacional de Estudiantes de Educación Superior con el objetivo de establecer rutas programáticas y movilizaciones para abordar la reforma a la Ley 30 de 1992, al mismo tiempo que se observan distintas disputas por la gobernabilidad universitaria y, en particular, la elección de rector en universidades como la Nacional de Colombia , la de Antioquia , la Tecnológica de Pereira y la Universidad Industrial Santander, entre otros.
The Impact of an Individual’s Narcissistic Traits on Employability
Authors: Król Małgorzata , Karczewska Monika
Published: July 2024

Objective: The objective of this paper is to identify narcissistic traits that may have an impact on an individual’s employability and to determine the nature of the influence of these traits on employability.
Research Design & Methods: During the first stage, based on a critical literature review, narcissistic traits were identified and a 20-item catalogue of traits affecting an individual’s employability was created. During the second, a diagnostic survey was conducted to determine whether the narcissistic traits in the catalogue have an impact on employability, what is the direction of influence of individual narcissistic traits on employability, and whether the nature of the influence of these traits on employability varies by type. The research sample was purposive and random. 198 respondents participated in the survey.
Findings: The obtained results confirmed that the proposed trait catalogue for studying the impact of narcissistic traits on employability can be considered as reliable. 13 narcissistic traits were found to weaken initial and internal employability, while 8 traits were found to weaken external employability. The trait that most significantly weakens employability is displaying a demanding attitude, while the most strengthening trait is a strong belief in the possibility of professional success. Assessments concerning the impact of narcissistic traits on initial and internal employability were similar. There were differences between assessing the nature of the impact on initial and internal employability and on external employability.
Implications / Recommendations: The studies confirmed that most narcissistic traits weaken employability, while some strengthen it. It was also found that the nature of the impact of narcissistic traits may vary by type of employability.
Contribution: The study showed how individual narcissistic traits affect employability. Also indicating the differences in assessing narcissistic traits in the context of initial, internal, and external employability. These findings may be useful in shaping individual employability.
Gen Y in Uncertain Times of Remote Working: From the Employees’ Perspective
Authors: Żarczyńska-Dobiesz Agnieszka , Janiak-Rejno Iwona , Chomątowska Barbara
Published: July 2024

Objective: The purpose of this article is to identify the experiences of Generation Y employees of remote work and to identify the key factors that, in their opinion, develop or limit its effectiveness and efficiency.
Research Design & Methods: The authors carried out a questionnaire (CAWI) which was filled in by 304 respondents from Generation Y who worked remotely during COVID-19. Descriptive statistics measurements were used in the analysis. The original questionnaire was based on two measurement scales: ordinal on the Likert scale and nominal (binary and categorical). Then, the two-way data analysis method was used. Due to the nominal nature of the variables, frequency and percentage statistics were used in the statistical evaluation. For variables on the Likert scale, measures of descriptive statistics were used. In addition, hierarchical clustering analysis was used as part of the conducted research. Quantitative research was supplemented by unstructured interviews, conducted with eight HR Business Partners.
Findings: The obtained results made it possible to conclude that workers from Gen Y have adapted quite well to remote work and were very involved in the workplace when working remotely. Unfortunately, they were also overworked and tired. Gen Y strive to effectively perform their duties, regardless of whether they work on location or from home.
Implications / Recommendations: The experience of remote work gained by organisations and employees during the pandemic was an opportunity to implement innovative solutions, suitable for pandemic and post-pandemic conditions of the functioning of enterprises in the remote work era.
Contribution: The article recognises and analyses the experiences of employees from the Y Generation who are professionally active, working remotely during COVID-19. The value of the study is the presentation of two perspectives on the experience of switching to a different mode of work organisation – remote mode. Conclusions drawn from the empirical research have an application value primarily for leaders, managers, and supporting departments, such as HRM.
On Bootstrap Algorithms in Survey Sampling
Authors: Żądło Tomasz
Published: July 2024

Objective: The aim of this paper is to present bootstrap algorithms for measuring the accuracy of estimation and prediction in design-based and model-based approaches in survey sampling and small area estimation. Three proposals of prediction-mean squared error estimators are also examined.
Research Design & Methods: Various bootstrap procedures are shown and used to estimate the design- and prediction-mean squared errors based on real data. Computations are supported by two R packages.
Findings: Three prediction-mean squared error estimators are proposed.
Implications / Recommendations: The bootstrap algorithms used in the design-based approach give similar results for the considered data for the variance estimates of the considered estimator, implying that the speed of the algorithms may be important for practitioners in cases of similar properties. The proposed estimators of the prediction mean squared error produce higher estimates than other estimators in the model-based approach, indicating a positive bias that can be interpreted as a pessimistic accuracy estimate.
Contribution: All the presented bootstrap algorithms are easily applicable using two R packages available at R CRAN and GitHub. Three double bootstrap prediction-MSE estimators are proposed and analysed in the real-data application.
Potential Effects of Some Factors on Psoriasis Course in Children
Authors: Gubanova Svetlana G. , Ambarchyan Eduard T. , Namazova-Baranova Leyla S. , Vishneva Elena A. , Zelenkova Irina V. , Gankovskiy Viktor A. , Aleshenko Nataliya L. , Kaytukova Elena V. , Kuzminova Anastasiya D. , Ivanchikov Vladislav V.
Published: July 2024

Psoriasis is the second most common skin disease after atopic dermatitis in childhood. There are factors affecting both the manifestation and aggravation of this inflammatory skin process. The leading role in the psoriasis pathogenesis is currently associated with key cytokines. However, infectious diseases could be the triggers for psoriasis.

Nowadays, the approach to psoriasis management in children has been revised due to emerging of new knowledge about the clinical manifestations and the role of numerous comorbid conditions in psoriasis course. Risk factors assessment, as well as evaluation of potential comorbidities signs and symptoms, is crucial part in patient management to create a prognostic model of the disease progression and the aggravation development (with underlying associated inflammatory processes included).
Current Clinical Guidelines for the Management of Patients with Glycogen Storage Disease
Authors: Averkina Natalia A. , Bagaeva Madlena E. , Baranov Aleksander A. , Vashakmadze Nato D. , Vishneva Elena A. , Gundobina Olga S. , Zhurkova Nataliya V. , Kaitukova Elena V. , Komarova Elena V. , Margieva Tea V. , Namazova-Baranova Leyla S. , Novikova Valeria P. , Petryaykina Elena E. , Platonova Mariya M. , Potapov Aleksander S. , Smirnova Olga Ya. , Strokova Tatiana V. , Surkov Andrey N. , Taran Nataliya N. , Fedoseenko Marina V. , Semenova Nataliya A. , Anisimova Inga V. , Repina Svetlana A. , Subbotin Dmitriy M. , Sviridova Valeria V. , Havkin Anatoliy I. , Yablokova Ekaterina A. , Volynets Galina V. , Sadovnikova Irina V. , Tumanova Elena L.
Published: July 2024

Glycogen storage disease refers to hereditary pathologies of carbohydrate metabolism, its cause is mutations of various genes encoding enzymes responsible for the synthesis and breakdown of glycogen. Due to enzyme defects, excessive glycogen deposition occurs in cells of various tissues, mainly in the liver and muscles. The authors present modern epidemiological data and features of the etiopathogenesis of glycogen storage disease, and give clinical characteristics of various types of this nosology. In accordance with the developed clinical guidelines, information is provided on laboratory, instrumental and morphological signs of glycogen storage disease in children, as well as on methods of treatment of glycogen storage disease. Due to the variety of clinical forms of glycogenosis, the article provides up-to-date information on three types of pathology that occur with predominant liver damage.
A Study on the Current Status and Needs of Inclusion Support Itinerant Education: Focus Group Interviews With Special Education Teachers at the Special Education Support Center of the Seoul Metropolitan Office of Education
Authors: Kang Eun Young , Joo Kyoyoung ,   The Korean Society of Special Education
Published: July 2024

The purpose of this study is to analyze the current state of operation and demands for a better direction as itinerant education for supporting integrated education is legally enacted. To this end, focus group interviews (FGI) were conducted with special education teacher. These teachers were in charge of integrated education support itinerant education for special education students attending schools without special classes at special education support centers of all local education support offices under the Seoul Metropolitan Office of Education. As a result of the completed interviews, five major themes, 16 minor themes, and 54 meaning units were derived. Based on the research results, directions for better integrated education support and itinerant education were discussed and suggested.
High School Special Education Teachers’ Perceptions and Needs Regarding Operation Plans and Support for the High School Credit System Elective Course
Authors: Cho Younghee , Son Jiyoung ,   The Korean Society of Special Education
Published: July 2024

This study explored the perceptions and needs of special education teachers regarding the operation plans and support for high school credit elective courses for students with special needs in inclusive education settings. A survey was conducted targeting 195 high school special education teachers across the country. The results of this study showed that teachers perceived that elective subjects can provide customized academic and career guidance for students with disabilities however, they also noted that the low desire of students with disabilities in various subjects and range of participating students should be taken into consideration. Additionally, it was recognized that additional special education teachers and specific guidelines are needed to operate elective subjects. In the case of online elective courses, it was recognized that blended learning and the development of online contents for different types of disabilities are necessary that it is appropriate to operate inter-school co-curricular programs as blended co-curricular programs within regular school hours on a fixed base school. For out-of-school education, it was recognized that the district office of education should provide both out-of-school education and classes taught by external experts in schools, and that it is necessary to secure out-of-school educational institutions and manage their quality. In order to operate elective courses for students with special needs in an inclusive education environment, the school-level support for students’ mobility is important, moreover, itinerant special teachers are needed to provide elective subjects at both the district and national levels. Based on these results, implication for the operation of high school credit elective courses for students with special needs in inclusive education settings and suggestions for further research are discussed.
Experiences of Special Education Teachers With Aggressive Behaviors in Students With Developmental Disabilities and Perceived Support Needs
Authors: Park Kyoung Ock , Oh Jungsook , Han Kyung In , Shin Yoonhee ,   The Korean Society of Special Education
Published: July 2024

This study aimed to identify the coping experiences and psychological experiences of special education teachers regarding the aggressive behavior of students with developmental disabilities, as well as the support needs required to mediate such behaviors. A survey was conducted with 310 special education teachers from special schools. The survey results were as follows. First, there was a statistically significant difference between the support needs and the special education teachers’ responses to each type of aggressive behavior they experienced. Applying the Locus for Focus model to identify aggressive behaviors that require top priority support, nine types of self-harm and physical aggression were selected as requiring the highest priority support. The burden of managing aggressive behavior was found to be the greatest, followed by psychological exhaustion, anxiety, and tension. Lastly, an analysis of the support needs for mediating aggressive behavior in students with developmental disabilities revealed that teachers emphasized the necessity of establishing a cooperative support system. Based on these findings, there were demands for administrative support, psychological counseling, and emotional support; furthermore, the importance of individualized interventions for challenging behaviors of students with developmental disabilities and the necessity of applying an ecological-based wraparound model were also shown to be a necessity. Related follow-up research was also suggested.
Science and Technology Studies and Affect in the Wild
Authors: Arthur Mathew
Published: July 2024

Expanding on comments made at last year’s Society for Social Studies of Science (4S) Meeting on a panel recognizing Donovan Schaefer’s Wild Experiment as the winner of the Fleck Prize, this article explores the book’s adjacencies in order to tell a “wild” story about place, Indigeneity, colonial sciences, messy methods in science and technology studies, and the implications of how affect is composed in words and worlds.
Changing Minds: Cogency Theory and Secular Bodies
Authors: van Emmerik Mari
Published: July 2024

This reflection on Donovan O. Schaefer’s Wild Experiment focuses on one angle of the multidisciplinary network of ideas explored in his book: the way cogency theory pertains to the theoretical discussion in psychology and secular studies. The beauty of cogency theory is identified to lie in its capacity to bring together conversations in philosophy, psychology, religious studies, and secularism studies, among other fields.
Love Affair with an Idea: Commentary on Wild Experiment: Feeling Science and Secularism after Darwin by Donovan Schaefer
Authors: Shah Esha
Published: July 2024

In this review essay, I discuss how, in writing this book on how thinking is feeling, Donovan Schaefer is having a passionate love affair with an idea, how he pulls the bow string as far and still not enough to the point of breaking. I have three remarks/points of concern/comments specific to the outline of cogency theory. First, how thinking is feeling? If thinking is feeling is a process, how does it happen? Second, where does reframing science/knowledge as thinking is feeling take us? How can it reframe what we mean by science? And last, who is the thinking-feeling scientist-subject?
Identification of novel biomarkers for lupus nephritis
Authors: Liao Zhengyue , He Liying , Fu Jiaojiao , Zhou Xiaotong , Li Yong , He Jing , Liu Yixin , Guo Jinlin , Liu Sijing
Published: July 2024

Lupus nephritis (LN) is an autoimmune disease that rapidly progresses as a secondary consequence of systemic lupus erythematosus (SLE) and has a very poor prognosis. Therefore, this study aimed to identify characteristics of immune cell infiltration and investigate potential therapeutic targets using bioinformatics methods and the Murphy Roths Large/lymphoproliferation (MRL/lpr) mouse model. In this study, a total of 2,810 differentially expressed genes (DEGs) were identified, which were primarily enriched in inflammatory and immune regulation pathways. From these DEGs, 226 immune-related genes (IRGs) were also identified. The single-sample gene set enrichment analysis (ssGSEA) revealed that patients with LN had increased infiltration of effector memory CD4+ T cells, effector memory CD8+ T cells, gamma delta T cells, myeloid-derived suppressor cells (MDSC), follicular helper T cells, Th1 cells, and Th2 cells, and this was closely correlated with the DEG-IRGs. Furthermore, the potential therapeutic biomarkers, CD244, S100 calcium binding protein P (S100P), and vascular endothelial growth factor C (VEGFC), were identified by Random Forest Approach (RFA), which were validated in LN mice. These findings provide new evidence and insights for further research on diagnosis and treatment of LN by identifying critical genes and their associations with immune infiltration.
Keman Yapımcılığında Yeniden Üretim: Kopya, Esinlenme ve Kişisel Temelli Uygulamaların Sınırları
Authors: Küçükebe Murat
Published: July 2024

Roma İmparatorluğu döneminde, heykeltıraşlar Yunan eserlerini başarılı bir şekilde kopyalamıştır. Rönesans döneminde de sanatçılar Antik Yunan ve Roma sanatının tekniklerini kopyalamış, Roma İmparatorluğu dönemi heykellerinden ilham almıştır. Antik Roma fresklerinin yeniden keşfi ve el yazması replikalarının yaygınlaşmasıyla, Antik Roma ve Yunan edebiyatı ve felsefesi yeniden keşfedilmiş, sanatçılar antik metinlerin replikaları ile bu eserlerin korunmasını sağlamıştır. 18. ve 19. yüzyıllarda, müze koleksiyonlarının oluşturulmasıyla birlikte, replika çalışmaları popülerlik kazanmış, replikalar, erişilebilirliği artırmak için kullanılmış ve sanat eğitiminde önemli bir rol oynamıştır. Günümüzde de sanat tarihindeki örneklerden esinlenen sanatçılar replika çalışmaları yapmaktadır. Keman yapımcılığı alanında da kopya olgusu ve yeniden üretim ile ilişkili uygulamaları, benzer süreçlerle ilişkili biçimde ortaya çıkmıştır. Otantiklik iddiasına dayanak olacak, doğrudan çalgının yapısıyla ilgili uygulama ve özellikler açısından keman, yapımcısına fırsatlar sunar bir çalgı durumundadır. Çalışma kapsamında bu özellikler, optik ve akustik olarak iki kısım altında ele alınmıştır. Optik özelliklerle ilişkili olacak şekilde yapımcılar arasında yeniden üretim biçimlerine ait kopya, eskitme/esinlenme ile kişisel model olarak adlandırılan üç farklı yönelim bulunduğu, keman yapımcıları ile yapılan görüşmeler sonucunda anlaşılmıştır. Keman yapımcılığında yeniden üretim uygulamalarının ortaya çıkışına etki eden ontolojik evren ile ilişkili biçimde söz konusu yönelimleri birbirinden ayıran temel farkın ne olduğu ve bu durumun uygulama üzerinde nasıl karşılık bulduğu sorgulanmış ve belirli bulgulara ulaşılmıştır.
Çocuklara Yönelik Toplumsal Cinsiyet Kalıpyargıları Ölçeğinin Ebeveyn Örnekleminde Geliştirilmesi ve Psikometrik Özellikleri
Authors: Işık Hatice , Şahin Acar Başak
Published: July 2024

Bu çalışma, ebeveynlerin çocuklara yönelik toplumsal cinsiyet kalıpyargılarını değerlendiren bir ölçek geliştirmeyi ve bu ölçeğin psikometrik özelliklerini incelemeyi hedeflemektedir. Çalışma, iki farklı ebeveyn örnekleminde (N = 597 ve N = 306) yürütülmüştür. Açımlayıcı ve doğrulayıcı faktör analizleri, kız ve oğlan çocukları için dört farklı boyut altında toplam 25 maddeyi işaret etmiştir. Ebeveynlerin kız ve oğlan çocuklarından beklentileri, toplumsal cinsiyet kalıpyargıları bağlamında teşvik edilen ve yasaklanan olarak birbirinden ayrılmıştır. Ölçeğin geçerlik ve güvenirliği, yapılan analizlerle desteklenmiştir. Bu bağlamda, ölçek, ebeveynlerin günlük yaşamda kız ve oğlan çocuklarından toplumsal cinsiyete dayalı beklentilerini anlamada ve bu beklentilerin gelişimsel süreçle ilişkisini araştırmada önemli bir araç olarak öne çıkmaktadır.
Phosphoglycerate kinase is a central leverage point in Parkinson’s Disease driven neuronal metabolic deficits. v1
Authors: C Kokotos Alexandros , not provided ama , Unda Santiago , Soo Ko Myung , Park Daehun , Eliezer David , G. Kaplitt Michael , De Camilli Pietro , Ryan Tim
Published: July 2024

The current collection contains all experimental protocols associated with the study "Phosphoglycerate kinase is a central leverage point in Parkinson’s Disease driven neuronal metabolic deficits".
Stop codon reversal assay v1
Authors: Sparrow is
Published: July 2024

This protocol is used to characterize viral RNA polymerase based directed evolution tools via fluctuation analysis to calculate the mutation rate. It is specific to the stop codon reversal of the aadA gene, which we use to characterize the mutational power of the tool.
Systematic literature review on PAI and needle positioning errors v1
Authors: Bloemberg Jette
Published: July 2024

This protocol aims to ensure the reproducibility of the systematic literature review carried out on the quantification of and current guidelines on the hazards related to needle positioning in prostate cancer treatment: (1) access restrictions to the prostate gland by the pubic arch, so-called Pubic Arch Interference (PAI) and (2) needle positioning errors.
TrpB passaging protocol v1
Authors: Sparrow is
Published: July 2024

Instructions for passaging the evolving TrpB populations using the OrthoRep system for continuous directed evolution. Protocol developed from Rix et al., 2020 and optimized in Burgess lab. Special thanks to Vincent Hu for his aid in troubleshooting.
Yeast transformation v1
Authors: Sparrow is
Published: July 2024

Protocol was obtained from Ulschan Bathe and Kristen Van Geller from UF on May 2023 and optimized by myself. This protocol is a variation on the highly efficient LiAc/SS/PEG method from Gietz et al., 2007 DOI:10.1038/nprot.2007.13
Genetic expression suppressor screen v1
Authors: C Kokotos Alexandros , Ryan Tim
Published: July 2024

This protocol describes a low-throughput genetic screen to identify glycolytic enzymes that improve neuronal function under hypometabolic conditions.
Positive test extract (PTE) aliquots v1
Authors: Schmidt Anna , Meyer Matthias
Published: July 2024

This document describes the preparation of FluidX tubes containing positive test extract (PTE). It is part of the library preparation workflow of the Ancient DNA Core Unit of the MPI-EVA.
A Scoping Review of dating behaviours in typically developing adults v1
Authors: Behn Nicholas , Hilari Katerina
Published: July 2024

This protocol details a scoping review of dating behaviours in typically developing adults.
Trajectories of Solitons Movement in the Potential Field of pPF1 Plasmid with Non-Zero Initial Velocity
Authors: Yakushevich L.V. , Krasnobaeva L.A.
Published: July 2024

Nonlinear conformational distortions, such as, for example, locally unwound regions of the DNA double helix, named open states, are considered in this work as solitons moving in the potential field of this molecule. It is believed that open states play an important role in the processes of transcription, replication, denaturation, as well as in the transmission of structural changes and information along the DNA molecule. This work examines the problem of the movement of kink-like solitons (kinks) in the potential field of the pPF1 plasmid, the sequence of which includes the genes of the fluorescent proteins Egfp and mCherry, separated by a small intermediate region. The results of calculations of energy profiles of the main and complementary sequences of the plasmid, as well as 2D and 3D trajectories of kinks with a non-zero initial velocity are presented. It has been shown that two types of kinks can be activated in the pPF1 plasmid, which can be considered as two types of quasiparticles that have their own energy, mass, velocity and move in the potential field of the plasmid. It was found that the lowest energy required to form these kinks is observed in the intermediate region located between the fluorescent protein genes. It was shown that the nature of the motion of kinks does not depend on the value of their initial velocity. It was shown that there are threshold values of the torsion field, upon reaching which the behavior of kinks changes sharply: from damped oscillations within the intermediate region to forward motion and penetration into neighboring regions. These values have been calculated. It turned out that for the first kink moving in the main sequence potential field, the threshold value is 4.95×10–22 J, and for the second kink – 4.20 × 10–22 J.
İyi Yönetişim ve Avrupa Birliği Vergi Politikası Kapsamında Yerel Vergi Gelirlerinin Analizi
Authors: Yılmaz Neslihan
Published: July 2024

Avrupa Konseyi tarafından 2008 yılında İyi Demokratik Yönetişimin ilkelerini kapsayan Yerel Düzeyde Yenilikçilik ve İyi Yönetişim Stratejisi kabul edilmiştir. Bu doğrultuda Avrupa Konseyi ve Avrupa Birliği (AB) temel hak ve özgürlükler ve çoğulcu demokrasinin güçlendirilmesi amacıyla birlikte faaliyet göstermektedir. Çalışmada, AB vergi uyum politikası, iyi demokratik yönetişim ilkeleri genelinde incelenerek; Üye Devletlerin 2008-2022 yerel vergi gelirleri ilişkisi Unweighted Pair Group Method with Arithmetic Mean (UPGMA) metodu, Cluster Analiz (CA) yöntemi ile değerlendirilmiş ve yerel vergi gelirlerinin dağılımı, Principal Component Analysis (PCA) çerçevesinde incelenmiştir. Uygulama sonucunda, yerel vergi gelirleri dağılımının, vergilendirme yetkisi ve yerel mali özerklik düzeyince değişkenlik gösterebildiği bulgusuna ulaşılmıştır.