bluuebunny/crossref_metadata_2025 huggingface dataset:
EFFECTS OF CELECOXIB AND ROFECOXIB ON NEUTROPHILES AND LYMPHOCYTE COUNTS IN RATS (COMPARATIVE STUDY).
Authors: H. Sheeh Adel
Published: January 2024

Non steroidal anti-inflammatory drugs NSAIDs one of the most commonly used drugs all over the world specially for treatment of chronic disease their effect on immune system should be considered in selection of member of non steroidal anti inflammatory drug The objective of this study is to determine whether Celecoxib and Rofecoxib are associated with a lower incidence leucopenia Thirty (30) Sprague-Dawely male rats were used during this study . The animals were divided in to three groups : group 1 â€“ Control , group 2 received Celecoxib and group 3 received Rofecoxib for 1 month duration .Samples of blood before and after treatment were taken for determination of total W.B.C , neutrophiles and lymphocyte counts. The results were as fallow:1-Celecoxib 15 mg/kg/day and Rofecoxib 10 mg/kg/daycaused significant reduction in total W.B.C , Neutrophiles and Lymphocyte counts .2-Rofecoxib 10 mg/kg/day caused the less reduction in total W.B.C. count, neutrophiles and lymphocyte counts ascompared with Celecoxib 15 mg.kg.day/ day
The effect of aqueous and alcoholic extracts of fruit pell of Punica granutum against Leishmania major in vitro and in vivo
Authors: H. H. Awad A. , M. Jarallah H. , H. Jassim A.
Published: January 2024

The effects of aqueous and alcoholic extract of Punica granatum, were studied against the activity and growth of promastigote of Leishmania major in vitro. The alcoholic extract was used by topical route against BALB/c mice infected with L.major. The alcoholic extract showed high activity against L.major promastigote than aqueous extract.
Bacteroides spp. isolation from pus or peritoneal fluid in patients with perforated peptic ulcer
Authors: Abd ALwahed Issra
Published: January 2024

From October 2001 till November 2007,two hundred eighty eight patients with perforated peptic ulcer including duodenal and gastric ulcer attending Baghdad teaching hospital and Al- Diwanyia teaching hospital were subjected for surgery and samples from free peritoneal fluid to obtain specimens for determining the rate of peritoneal colonization by bacteroides spp.and the risk factors which may increase this rate by direct questionnaire to obtain preliminary guides for methods of prophylaxis against subsequent possible wound infection and systemic sepsis .Specimens was obtained using sterile syringe aspirating about 2-5 ml of pus or fluid which is air free Diagnostic confirmatory tests for Bacteroides spp. identification has been made by anaerobic culture utilizing selective complex medium like brain heart agar containing amikacin which inhibit growth of facultative anaerobes. Culture were incubated at 35- 37c in an anaerobic atmosphere containing CO2. Results showed that 48.6% of the studied patients were found to be Bacteroides culture positive . Some risk factors have been evaluated which may or not contribute to increasing the rate of Bacteroides spp. Colonization, among these ,time from onset of perforation till the time of surgery or sampling which was found to be a significant risk factor if the patient underwent surgery after 12hr from onset of perforation 72.5% . Age was individually evaluated , it has appeared that increasing age is a risk factor and become significant after 50 years of age with 83.7% of patients in this age group was colonized with Bacteroides spp. The associated other medical illness , steroids consumption and immune suppression were also evaluated in which only steroids found to be a significant risk factor with a rate approaching 80.4%. Other risk factors which has been evaluated is the preoperative use of H2 blockers or proton pump inhibitors , which found to significantly increase the rate of bacteroides isolation( 80%.).
Antimicrobial Susceptibility Patterns of Uropathogens in Obstetric patients
Authors: Ghaly Mohamed Kareem , Nory Gany Sarmad , Abdullah Mahmood Thukra , Ahmed Al-Sagheer Hanaa
Published: January 2024

Across-sectional study was done to know the patterns of antimicrobial Susceptibility test of isolated uropathogens among pregnant women attending the Department of Gynaecology/Obstetric at the maternity&Child Teaching Hospital in Najaf Governorate.The study was conducted during the period between August 2006 to August 2007 .The study showed that 28%of pregnant women whom complained of signs & symptoms of urinary tract mfection (UTI) had a positive cultural result .The predominant pathogen was E.coli (44%) with high susceptibility test result to cefotaxim , ciprofloxacin , amikacin, and a high resistant rate to trimethoprim/ sulfamethoxazole & ampicillin.
Expression of p16INK4a Protein in Colorectal Cancer Patients
Authors: D. Chalap Al- Grawi Eqbal
Published: January 2024

This study carried out on Forty-three patients attending hospitals for elective surgical resection of colorectal cancer (CRC) from October 2002 to March 2004. Thirty-five resection margins that histopathologically proved free of malignancy taken from the normal tissue of the same patients used as controls of staining efficiency and evaluation for immunohistochemistry (IHC). p16INK4a immunoexpression in the CRN are less than 5% and regarded as negative while 32 of 43 CRC patients had positive reaction for p16INK4a.
Investigation of Human Cytomegalovirus pp43 & pp76 in colon adenocarcinoma Using Immunohistochemistry (IHC) technique
Authors: Gitti Allawi Atta , A.Samad A.Bassit , M.A.Nazar Ahmed
Published: January 2024

Several studies have suggested a possible link between human cytomegalovirus infection and various malignancies particularly colon adenocarcinoma.The present study investigates whether HCMV participates in human colon tumorigenesis by the detection of HCMV proteins within epithelial cells of colorectal carcinoma using Immunohistochemistry (IHC) technique.formalin â€“ fixed, paraffin â€“ embedded specimens of adenocarcinoma, and normal tissues were obtained from the margins of the excision as a control, those specimens were tested by IHC to detect the presence of HCMV proteins using two types of mouse monoclonal antibodies as mixture of monoclonal antibodies to an early and immediate early proteins (pp43 & pp76, respectively). The results of IHC assay showed specific nuclear and cytoplasmic reaction of HCMV proteins within the epithelial cells of colon adenocarcinoma (82.60%), the study showed no nuclear or cytoplasmic reaction in any case of control group . In view of the many cellular modulatory properties of this virus, our data justify further studies to establish whether HCMV interfere with the pathogenesis of colon adenocarcinoma.
Management of Rachipagus Parasitic Twin
Authors: J. Aboud Mohammed
Published: January 2024

Occurrence of asymmetrical or parasitic conjoined twins (CT) is rare, and currently they are classified analogically to the common unions of symmetrical CT. We report on an infant with a parasitic third limb attached to the back at thoracolumber area , in whom male genitalia was found . Parasite parts included incomplete upper limb, hemipelvis, thoracolumber vertebral column, spinal cord, and one kidney with ureter ,small bowel, lung tissue and adrenal gland. Auto site anomalies comprised evidence of thoracolumbar meningomyelocele. We considered this case to be a rare atypical parasitic rachiopagus CT. The differential diagnosis of the type of twining and other entities with caudal duplications is analyzed briefly . We report a case of rachipagus parasitic twin diagnosed delivered a live baby at 34 weeks of gestation to 30-year-old primgravida woman with history of 10 years secondary infertility .
Prevalence of patients with Failure to thrive admitted to Maternity and Children Teaching Hospital in Al- Diwaniyah
Authors: Naji Al-Hijia Nasma , Nasir Al â€“ Obaidi Jomah
Published: January 2024

This is a prevalence study of patients with failure to thrive under 5 years who were admitted in maternity and children teaching hospital in Al â€“ Diwaniya from 1 / 7 / 2008 to 1 / 9 / 2008 .The total number of patients under 5 years was 420 patient , 59.40% was male , and 40.95% was female . The patients under 1 years of age were 66.66%, from 1 year to 2 years age was 20.47%. From 2-3y.(7.14%),from3- 4y.(3.78%),from4-5y(1.90%). The prevalence of patients with failure to thrive was 50.71% , the patients with failure to thrive due to organic causes was 48.33% , and inorganic causes ( psychosocial ) was 2.38% . The prevalence of patients with no FTT was 49.28%.
Desmoid tumors of the abdominal wall:Two cases report.
Authors: M. Al-Rekabi Adel
Published: January 2024

Desmoid tumors are slow growing deep fibromatoses with aggressive infiltration of adjacent tissue but without any metastatic potential.We report on two female patients with desmoid tumor of the abdominal wall who underwent primary resection and proline mesh repair. Bothpatients had a history of an earlier abdominal surgery. Preoperative evaluation included abdominal ultrasound,and computed tomography. The histology in both cases revealed a desmoid tumor.Complete surgical resection and proline mesh repair is the first line management of this tumor entity.
Occurrence of Salmonella serotypes in Euphrates River Water at A-Nassyria city-Iraq
Authors: Abedelreda Abass Yahia
Published: January 2024

The study was undertaken from April to September 2007 to detect occurrence of Salmonella serotypes in Euphrates river water and its correlation with two indicator organisms (FC & FE) of water contamination. Three stations for study were selected on the river at Al-Nassyriya and one on sewage effluent. High influence for sewage effluents on bacteriological properties of river water (through counting large number of indicators) were found specially in station 2 which lies at the area of sewage effluent outlet with the river and lead to increase of pathogens counts. Salmonella were found in all samples of stations 2,3,4 and in 70% of station 1.The most frequently serotypes were S. anatum (22.72%) and S. typhimurium (20.9%).
The outcome of electrocoagulation after dissection in thyroglossal duct cyst and fistula
Authors: M-AL-Rubaiee Khairallah
Published: January 2024

Thyroglossal duct cysts are the most common forms of congeLital neck swelling .They are liable for infection &also for malignant transformation .Incorrect management of the infected cyst may end with formation of thyroglssal fistula. Sistrunkâ€™s operation is still the procedure of choice in spite of its recurrence rate about4 %.In this series 32patients underwent the conventional Sistrnkâ€™s operation with moderate modification represented by electocoagulation of the dissected plane of tissues. Twenty eight patients (88%) of the total series were presented with asymptomatic naci swelling; 6%with inflamed neck swelling; 6%with TGD fistula; they were scheduled to undergo the above surgical operation over a period of 4.5years .average age was9.125year; male: female ratiowas1.8:1 Recurrence rate was0%; the mean follow up period was 18 month, 6%of them presented with post operative complications. Electrocoagulation of the dissected plane of tissue in Sistrunkâ€™s probably offer more warranty for ablation of ductuli & thence minimize the recurrence rate.
The Effect of Obesity on Blood Pressure
Authors: H. Ali Al-Naily Farhan
Published: January 2024

The aim of this study to quantify the effect of obesity on blood pressure. We study 80 persons (clinically normal), divided in two groups according to the age, the first group under 40 years which is subdivided into two groups, group A 20 persons with normal weight and group C also 20 persons with over weight and the second group, above 40 years also subdivided into two groups, group B 20 persons with a normal weight and group D 20 persons, with over weight and we have found the effect of obesity on, systolic, diastolic, and mean blood pressure on the first group and on the second group.And the results indicate that the effect of obesity on the age group over 40 years more than the effect of obesity on the age group, below the 40 years. So the effect of obesity on SBP, DBP and MBP is increase with the increasing of the age.
Elevated leukocyte count and advers events in patients with acute coronary syndrome
Authors: M.HUSSAIN AL.YASSIAN ALI
Published: January 2024

Inflammation has been shown to play a role in atherosclerosis and CAD. An elevated leukocyte count is associated with adverse inhospital out come and mortality in patients presented with acutecoronarysyndrome. This study was designed to determine the relation between initial total WBC count and the hospital mortality and complications in patients with ACS including STEMI, NSTEMI, and UA and to know if this parameter has significant power of clinical severity and out come. Patients and methods: The relationship between initial total WBC count with hospital mortality and complications and clinical out come in 57 patients with ACS admitted to the CCU in ADDIWANYIA teaching hospital from the first of January to the 30 of march 2008 has been tested ,diseases were evaluated for seventeen (17) patients with STEMI ,twenty (20) patients with NSTEMI , twenty (20) patients with UA , venous blood samples were taking from each patient for initial total WBC count ,fasting lipid profile ,random blood sugar. Comparison between those patients with STEMI, NSTEMI, UA were conducted includes one inflammatory marker (WBC). High initial total WBC count was associated with high cardiovascular risk, heart failure and mortality (19.2%, 12.2 %, and 8.77 %) among patients with STEMI, NSTEMI, and UA respectively. Conclusion: In patients with ACS, initial leukocyte count is predictive of out come and as the level increased the complications increase and the clinical out come adversely affected.
Misoprostol for termination of first trimester missed abortion.
Authors: Assim AL- Azzawy Maha
Published: January 2024

Background: misoprostol is prostaglandin E1 analogue that can be given by oral, sublingual, vaginal or rectal route. It is cheap and can be stored at room temperature and because of its utero-tonic action, it become an important drug in obstetric and gynecological practice.Objectives: to evaluate the effectiveness of intravaginal followed by oral misoprostol tablets for medical termination of missed abortionbetween 8 â€“ 13 weeks.

Methods : a prospective study of (60) women with diagnosed missed abortion admitted to AL- Zahraa General hospital â€“ Wassit Governorate Iraq from July 2006 through July 2007 . 800 micrograms (4 tablets) of misoprostol inserted in the posterior fornix of the vagina after moisture with normal saline followed by oral 400 micrograms (2 tablets) 6 hours later. Another 400 micrograms were given orally 6 hours from the last dose for those patients whodid not respond to theprevious two doses.Results: (48) patients (80%) had complete expulsion . (21) Patients (35%) after the vaginal dose. (15) Patients (25%) respond after the first oral dose and (12) patients (20%) after the second oral dose. (6) Patients (10%) had incomplete abortion; the remainder (6) patients (10%) failed to respond within 24 hours of starting treatment and require surgical evacuation. The mean time for expulsion was 10 hours.Conclusion: first trimester missed abortion medical termination by misoprostol is effective, save and a practical Methods .
Evaluation of humoral immunity against measles virus in Al-Najaf Governorate /Iraq.
Authors: A.Muhsin Mohammad , A.K.Al-Sa'adi Mohammed , .M.Sarah Anwar
Published: January 2024

This study was conducted to evaluate the anti-measles IgG antibody (AMAb) titers of measles vaccinated and non vaccinated normal individuals in Al-Najaf Governorate. "ELISA" test was applied to test 375 collected sera samples during April to November 2006. Individuals included with age range (1-30) years; 335 of them were vaccinated, and 40 non vaccinated (control group).Age, sex, residency and history of measles vaccination were recorded for each individual. The results revealed; that the highest IgG titer (234.82) had been seen in age group (A, age rang 1-6 year) and the titer was decreasing with increasing of age and reaching to the lowest IgG titer (6.6087) in age group (E, age range 25-30 year). The residency and sex of individuals was showed no significant differences(p >0.01) in AMAb IgG titers.
TAUS versus TVUS in detection early pregnancy complication
Authors: Majeed Hameed Amjaad
Published: January 2024

Background:Using TVUS(transvaginal ultrasound ) visualization of pelvic organ is limited due to attenuation of ultrasound beam byintervening anterior abdominal wall and pelvic fat while TVUS (high frequency transducers 5-7MHz) now day regard important revolution in diagnosis of early pregnancy and their complications ,because it facilitate high resolution image of target organ uterus , adenaxa and cul de sac.Aim of study:To evaluate TVUS in detection of early pregnancy complication and compare transvaginal approach with TAUS . Patient and Methods :Sixty four patients were included in this study all of them have positive pregnancy test with signs and symptoms of early pregnancy complication .All of those patient examine by TAUS than by TVUS .with good explanation of the procedure to the patients .Results:From sixty four patients a twenty five patients has normal intrauterine pregnancy all of them are diagnosed by TVUS while only 12 diagnosed by TAUS.Five patients have blighted ova all of them are diagnosed by TVUS and only 2 diagnosed by TAUS. All of 6 patient with subchronic hematoma are diagnosed by TVUS only 4 diagnosed by TAUS . Three cases were diagnosed as ectopic pregnancy and all of them are diagnosed by TVUS only 1 diagnosed by TAUS . Two patient that diagnosed only by TVUS had intact gestational sac in the adenaxa with positive heart pulsation in fetal pole.Incomplete abortion diagnosed in 8 patient all of them diagnosed by TVUS , only 3 diagnosed by TAUS Fourteen patients has missed abortion only 8 of them are diagnosed by TAUS .Conclusion and Recommendation:TVUS is more sensitive and more accurate in diagnoses of normal early pregnancy and in detection of early pregnancy complication.Many patient refused TVUS. So good explanation of the procedure to the patient is important.
In vitro culture of plasmodium berghei using glucose and reticulocytes enriched blood cells
Authors: Majeed Dakhel Khalid
Published: January 2024

In vitro culture of erythrocytic stages of malarial parasite can prove helpful in understanding the biology of the parasite to locate new targets for drug designing and vaccine development. In the present study an attempt has been made to assess certain in vitro conditions which can provide the amiable environment for continuous growth of rodent malaria parasite, Plasmodium berghei. A total of eight different conditions were studied out of which G type proved to be the mosteffective in maintaining long-term in vitro culture of P. berghei. G type contained medium RPMI-1640 supplemented with HEPES, sodium bicarbonate and glucose, normal mouse serum and phenylhydrazine hydrochloride (PHC) - induced reticulocyte rich blood. The viability of the parasite in long-term culture was assessed by i.p. injections of 1 x 105 P. berghei- infected erythrocytes from terminated culture pellets after every 24h till 7 days in normal mice.
Dose the shape of epiglottis have a role in the globus pharynges?
Authors: Majeed Hameed Husam
Published: January 2024

Back ground: globus pharyngeus is a sensation of a lump or tightness in the throat, it accounts for about 4% of otolaryngological referrals. A wide variety of explanations have been done; gastroesophageal reflux or esophageal dysmotility are the most popular organic explanations.Objective: To evaluate the incidence and the role of the curled epiglottic tip touching and indenting the tongue base in patients with globus pharyngeus.Patients and method:Two group were selected; group A (40 patients) selected according to selection criteria from a number of patients diagnosed as globus pharyngeus patients , a flexible nasopharyngoscopy was done searching for the incidence of an epiglottic tip touching and indenting the base of the tongue, for instillation of a few drops10% xylocain done and the disappearance of the globus sensation was reevaluated again. Group B (40 patients) selected randomly from patients examined for non-globus complaint, and again searching for the incidence of an epiglottic tip touching and indenting the base of the tongue where studied.

Results and Discussion: Group A:In 65% (26 patients), the epiglottis touching and indenting the tongue base, 88.5 % (23 patients) out of these 26 patients showed positive response to local anesthesia; so globus sensation temporarily disappeared. (P value < 0.01) was highly significant, and this might mean: pressure effect of curled epiglottic tipwhich had been temporarily eliminated. Group B: only 7.5% (3 patients) had an epiglottic tip touching and indenting the tongue base, while 37 patients had the epiglottis not touching the tongue base in both resting and the protrusion position . ( p- value >o.1 ) was not significant ; so this might mean that the curled epiglottic tip touching the tongue base is not a common finding in people or patients other than patients with globus pharyngeus .Conclusion: A curled epiglottic tip indenting the tongue base may be a cause of the globus sensation when there is no other pathology found.
Clomiphene citrate in the management of oligoasthenospermia
Authors: Kadhum Daher Ameer
Published: January 2024

Background: Although clomiphene citrate (clomid) is, anti-estrogen, typically used for women with fertility problems, there have been a variety studies as to the use of clomiphene citrate in treating male subfertility.Objective: To evaluate the role of clomid in treating male with oligoasthenospermia.Methods: A prospective clinical study of 40 men with preliminary diagnosis of oligoasthenospermia according to WHO protocols in Wassit Government Iraq from July 2007 through July 2008.Clomid 50 mg oral daily dose was given for 4 months. The changes in sperm counts, the percentage of active sperms, pregnancy rate and side effects were recorded and analyzed.Results: The mean sperm count before treatment was 11millions per ml, while the mean percentages of sperm motility were 15%. After treatment the mean sperm count increased to 35 millions per ml (3 times) and the mean percentage of motile sperm to 30 % (2 times).8 patients (20%) reported their wives became pregnant.4 patients (10%) failed to respond.

Conclusions and recommendations: In patients with normogonadotrophic oligoasthenospermia, clomiphene citrate improves sperm counts and motility and probably increase pregnancy rate.This can possibly convert the choice of treatment from IVF/ICSI to less costly IUI.Also it may save some women from being treated for a problem of male infertility.However, controlled trails with larger number of patients are needed to confirm the findings of this study.
Orthostatic hypotension and dizziness among insulin dependent diabetic patients
Authors: Jabbar Dibby Hudda
Published: January 2024

This study was carried out on 90 patient with insulin dependent for at least 10 year those attending the diabetic clinic and internal medicine consultation unit in Al-Diwamiya Teaching hospital and some popular clinic in Al-Diwaniya city and a 120 age and sex match control subject from patients relatives and medical staff. The blood pressure was measured in supine and standing position for each subject, orthostatic hypotension was defined as a decline in systolic blood pressure of 20mmHg or more one minute after standing, postural dizziness was any feeling of dizziness, light headedness, or faintness that occurred while standing. The prevalence of orthostatic hypotension and postural dizziness was higher in patient with diabetes than in control subject from the 90 diabetic patient a 27 develop orthostatic hypotension while only 16 subject develop orthostatic hypotension from the 120 non diabetic control subjects. Those patients with diabetes and had orthostatic hypotension were older and with high fasting glucose level and higher supine systolic blood pressure and lower standing systolic blood pressure than those without orthostatic hypotension. Postural dizziness among the diabetics patient were higher than its prevalence among non diabetic subject, and there was no significant difference between those who had orthostatic with postural dizziness and postural dizziness without orthostatic hypotension in both diabetic and non diabetic control subject.
The relationship between acute myocardial infarction and mood disorders
Authors: Z Alshibani Mazin , N. Hussain Karem
Published: January 2024

Acute myocardial infarction (AMI) acts as an important risk factor for occurrence of depression, which affectS long term morbidity and mortality considering baseline health state in patients with AMI.To estimate frequency of depression among patients within first 3 weeks after occurrence of AMI and to evaluate the effect of different demographic factors, biochemical changes, type and site of M.I on its frequency. This is a cross sectional study that enrolled 116 patients with AMI who had been admitted to coronary care unite (CCU) at Al-Diwaniya Teaching Hospital during the period between 1st of July 2007-31st of October 2008. Only 80 patients were followed up the Diagnosis of depression was done according to criteria of structural clinical interview for diagnostic and statistical manual of mental disorder-4- revision (SCID-DSM-4-R).This study revealed that 22.5% of patients had post-AMI depression. The females constitute 88.89% of depressed group, â‰¥ 65year old age were 44.44%, patients with hypertension and hyperlipidemia were 66.67%, diabetic patients were 27.78% and patients had positive history of MI were 33.33%. Patients with ejection fraction (E.F) < 35%, renal failure or insufficiency, chronic obstructive pulmonary disease (COPD) and anterior MI were 22.22%. Patients with non ST elevation myocardial infarction (NSTEMI), peak creatine phosphokinase (CPK) â‰¥500 u/l and current smoker constitute 66.67%, 55.56% and 16.67% respectively. This study proves that depression after AMI was more common in females and less common in diabetic patients, current smokers and patients with COPD.
The Effects Of Metformin And Pioglitazone Versus Their Low Dose Combination On Progression Of Atherosclerosis.
Authors: I. Mohammad Bassim , M. Jawad Haidar
Published: January 2024

Background: Atherosclerotic diseases remain the leading cause of death in men and women world wide. In addition to lipid lowering, reduction of atherosclerotic disease will require further pharmacological approaches capable of modifying the disease. Materials and methods: 35 rabbits were used in this study. Atherosclerosis was carried out by feeding the rabbits an atherogenic diet (AD). The rabbits were randomly assigned into five groups, 7 rabbits each. Group 1 (normal control) received standard chow diet. In addition to AD, the rabbits in group 2 (atherogenic control), group 3 (Met), group 4 (Pio) and group 5 (Met+Pio) received no treatment, metformin, pioglitazone and combination of low doses of metformin and pioglitazone respectively for 10 weeks. At the end of 10th week, all rabbits were sacrificed; serum lipids, MDA, GSH, hsCRP, plasma fibrinogen and aortic histological examination were determined. Results: Metformin and pioglitazone resulted in significant decrease (p<0.01) in AI. Further they caused significant (p<0.01) reduction in serum MDA, hsCRP and plasma fibrinogen. Serum GSH level was significantly (p<0.05) elevated by metformin. Combination treatment decreased AI, serum MDA, plasma fibrinogen and hsCRP, increased GSH and possessed more favorable histological findings better than either drug alone.Conclusion: low doses combination of Met+Pio has more favorable atheroprotective effect than either drug alone possibly due to the combined anti-inflammatory and antioxidant effects.
Expression of HLA Class 1 In Iraqi Bladder Cancer Patients
Authors: Hamed Ghali Kareem
Published: January 2024

HLA types studied in sixty bladder cancer patients. A control sample of 80 apparently disease free individuals was included for comparisons, matched for ethinical background (Iraqi Arabs), sex and age. The study demonstrated significant deviations in four antigens, HLA -A2, -B5, -B51 and -Cw7, when comparisons was made between patients and controls. The frequency of antigen Cw7 was increased in the patients, while antigens A2, B5, and B51 showed decreased frequencies. Other associations were also observed when the tumour staging and grading were considered.
Determination The Levels Of C-Reactive Protein In Rheumatoid Arthritis Patients In Babylon Province/Iraq.
Authors: A.Ekheiwsh Al-khafaji Zaitoon
Published: January 2024

Immunological and Inflammatory reaction play a pivotal role in the initiation and perpetuation of rheumatoid arthritis .The present study is an attempt to measures the level of the rheumatoid factor antibody and to estimate the level of c-reactive protein in blood as a marker for inflammation in patients with rheumatoid arthritis in Babylon government . A total of (89) cases presenting rheumatoid  arthritis with age range (9-68)years old of both sex and (25)person healthy controls were included in this study . Serum RF was detected using(Humatex RF kit) and c - reactive protein was detectedusing(Humatex CRP kit) which is a rapid agglutination test .CRP test was found to be positive in 84/89 cases of RA .
Psychoneurotic Profiles Of Thalassemia.
Authors: Al-Hamzawi Ali , Kh. Suhaim Sami
Published: January 2024

Background:Thalassemia is chronic disabling disease which have both physical and psychological consequences. Thalassemic patients are receiving medical care that is the focus of major attention with lesser focus on the psychiatric aspect of the illness. Early diagnosis and appropriate management of psychiatric disorders among thalassemic patients may improve the outcome , prognosis and overall quality of patients life.Objectives :To determine psychoneurotic profiles in thalassemic patients and to find out rates of anxiety, phobia, obsession, somatization, depression &hysteria. Method:The sample of the study was consisted of case group and control group. Each of the two groups include 80 thalassemic patients and 80 normal people respectively. The self-rating inventory Crown Crisp Experiential Index( CCEI) has been used to study their psychoneurotic profiles.Results :The study revealed that the frequency of psychiatric morbidity was significantly high among thalassemic patients.The rate of psychiatric symptoms was 87.5% vs.21.25% among thalassemic free people.The rate of somatization(92.5%), phobia(88.8%), anxiety(85%), obsession(83.8), hysteria(81.3%) and depression(76.3).The most common psychiatric symptom was dizziness and shortness of breath and the least common one was feeling loss of sympathy with others.Conclusions :The psychiatric morbidity of thalassemic patients is remarkable and suggest that all patients with thalassemia should undergo psychiatric assessment and Psychosocial aspects need to be addressed in the overall treatment of children with thalassemia.
Detection Of Secondary Infection In Cutaneous Leishmaniasis.
Authors: AL-Hucheimi Sundus , Ch.Abass Ebtihal , M. Abdul-sada Karrar
Published: January 2024

In order to study the prevalence of secondary infection in cutaneous Leishmaniasis and its relationship to the healing process , 76 Leishmaniotic patients were evaluated by three methods . The percentage of positive cases by injection with normal saline, part of skin biopsy and blood drops from lesion was 39 (68.4 %), 48 (84.2%) and 37 (65%) respectively while the percentage of nagative cases was 18 (31.6%), 9 (15.8%) and 20 (36%) respectevely . Secondary infection only were present in 57 (75%) patients, secondary bacterial infection were found in 52/ 57 (91%) patients , Secondary Fungal infection was found in 5/57 (9%) patients , gram positive bacteria only were present in 48/52 (92%) , gram negetive bacteria were present in 4 /52 (8%) patients.   The secondary infection gram positive bacteria which appear  Staphylococcus aureus 45/48 (93.7%) ,Streptococcus pyogenes 2/48 (4.2%) ,Staphylococcus epidermidis 1/48 (2.1%) , While gram negative bacteria appear Escherichia coli 2/4 (50%) ,Pseudomonas aeruginosa 1/4 (25%), klebsiella spp. 1/4 (25%) .
Macroscopical and microscopical study of placenta in normal and in pregnancy induced hypertension
Authors: Hady Lateef Al-Mamori Rafah
Published: January 2024

Placenta was an indicator of maternal and foetal disorders. Many of the disorders of pregnancy which are associated with high prenatal morbidity and mortality are accompanied by changes in placental histology. The current works was an analysis of gross and histological changes of placenta in hypertensive disorders of pregnancy. A total of 50 placentas are studied 25 placenta from hypertensive pregnant mothers and 25 from non hypertensive pregnant mothers. The morphmetric parameters in hypertensive group revealed that there is an increase in the mean placental weights, mean placental diameter and mean birth weights in comparison with normal group.

The analysis of macroscopic placental changes showed decrease in the mean number of cotyledons and increase in mean number of calcified areas as well as an increase in the number of marginal insertion of umbilical cord.The histological appearance of placenta in hypertensive pregnant mothers revealed increase in hyalinized spots and areas of calcification also a medial coat proliferation of medium sized blood vessels are observed . In conclusion the hypertensive disorder of pregnancy well reflected on mother placenta.
Extended spectrum ÃŸ-lactamase (ESBL) mediated resistance to third generation cephalosporins in urinary tract infection isolates of Klebseilla pneumonia
Authors: Muhsin Almohana Ali , Jabir Hadi Zainab , Abdul- Hadi Suad
Published: January 2024

Objective: To examine the dissemination of extended spectrum ÃŸlactamase (ESBL) producing isolates of Klebseilla pneumoniae obtained from patients with significant bacteriuria.Methods: ESBL and multiantibiotic resistance were studied in a total of 25 isolates of K. pneumoniae.Results: all isolates found resistance to at least five of the antibiotics used in this study. All the isolates were found sensitive to the antibiotic imipenem. 5 (22.7%) of these isolates were ESBL producing. The ESBL producing isolates were more resistant to antibiotics than non-ESBL isolates.

The ESBL activity could be experimentally transferred to recipient Escherichia coli MM294.Conclusions: present study has found the occurrence of ESBL producing K. pneumoniae isolates in Najaf hospitals. Test for the detection of ESBL producing bacterial isolates should be carried out in all diagnostic laboratories routinely and the therapeutic use of all the third generation cephalosporins should be avoided against bacterial isolates that appear resistant to any third generation antibiotic.
Anterior cervical decompression and fusion using cage and autogenously graft
Authors: AL-Dahhan Musaed
Published: January 2024

Aim:Use of cage and bone graft for decompression and fixation cervical spineMethods:Fourty patients between june2004 _ june 2006 , evaluated by physical and neurological examination with radiograby by x Ray and MRI . the treated by anterior disectomy and replaced by cage and bone graft.Results:Regarding the site of disc prolapsed (10%) between C4 - 5(65%) between C5 -6 and (25%) between C6-7 . 37 patients treated disectomy by and bone graft while two Patient treated by corpectopmy of C5,6 body The complete recovery presented in 80% , incomplete recovery in 7,5% while no any improvement in 2,5%Conclusion:Immediate stability with good clinical improvement and no graft morbidity are the advantage of this implant compared to conventional interbody grafting techniques .
The correlation of C- reactive protein and diabetes mellitus type 2
Authors: A. Abdul Hussein Mohammad , R. Hadi Najah , A. Hussein Mohanad
Published: January 2024

Aim of study:To evaluate the association between C-reactive protein (CRP) and type 2 diabetes mellitus .Method:The study sample consisted of (65) patients with type 2 diabetes mellitus( 40) men and (25) women. The CRP was measured for all them and compared with (65) persons without DM as a control group well matched with age and sex to the patient group .BMI for patients in both groups were measured . A p-value of <0.05 was regarded as statistically significant .Result: 40 males and 25 females with type 2 DM with mean age 60.7 years. The increase in CRP was significant ( p value<0.05) in type 2 DM patients who are male with high BMI and increased age while no significant increase in the level of CRP in the control group ( p value > 0.05) .Conclusion : These result suggest, that there is an association between CRP and type2 diabetes mellitus .
The relationship among mother ages, months of year, gender of neonate and congenital malformation in AL-Najaf city
Authors: Sallal Abdul Hadi , Adeeb Mahdi Leena , Abdul- Razak Azis Methak , Kadhim Ibadi Atheer
Published: January 2024

The present study carried out on (249) cases of pregnant women deliver neonates baby with congenital malformations in ALZahra hospital for birth and childhood in AL- Najaf city, during the period (1/1/2005 to 31/12/2008). To determine the relationship between congenital malformations, age of pregnant women, neonate's sex and seasonal period during four years (2005, 206, 2007 and 2008). The results related biostatic significant information at (p>0.05) that the high rate of congenital malformations which occurred between (21-33 year) of the maternal ages. Our observations about year months which related to the malformations appearing the June and July in the years (2005, 2006 and 2007) was recorded highest percent of congenital malformations. From another hand, this present study revealed that high rate in female neonates than the male neonates when compared the neonates gander with congenital malformations.
Evaluation of Anticoagulant Therapy for Atrial Fibrillation in Babylon
Authors: Hashim Al-Yasiri Hasanain , Badr Al-awadi Najlaa
Published: January 2024

Background: Atrial fibrillation (AF) is a common cardiac arrhythmia and is a major independent risk factor for peripheral thromboembolism mainly strokes. Anticoagulation with vitamin K antagonists is the most effective therapy for stroke prophylaxis in AF.Methods : In this study; 236 patients were included complaining of sustained or paroxysmal AF. They were admitted to medical ward or attended outpatient clinic in Al-Hilla Teaching Hospital in Babylon governorate during the period from 1st Jan. 2008 to 1st Jan. 2010. At the time of enrollment; INR was done for all patients and previous INR results were requested and reported. Stable therapeutic anticoagulation was defined as two INR values (measured at least two weeks apart) were within or above therapeutic range. Then patients were classified into different stroke risk groups. Based on these categories; treatment modalities, it's effectiveness and compliance were calculated. The antithrombotic therapies were considered consistent with guidelines when OAC was prescribed for high and intermediate (subtype A) risk groups and acetyl salicylic acid-aspirin (ASA) was prescribed for intermediate (subtype B) and low risk groups. The patients on OAC were considered "within target INR range" if INR was within recommended target range in 50% or more of occasions.

Results : A total of 236 patients with AF were studied; age range was 18-86 years, 58.5 % (138/236) of them were males. 38.6% (91/236) of our patients were on recommended treatment according to guidelines recommendations. 55.1% (130/236) of our patients were ideally indicated for OAC therapy and only 43.1% (56/130) of them were on OAC therapy. 35.2% (83/236) of our patients were in high risk group and only 44.6% (37/83) of them were on OAC therapyConclusion : There is a clear under-treatment of AF in Babylon even in patients with high stroke risk, and the patients on OAC therapy weren't achieving target INR.
Modified Tension band& longitudinal K .wires fixation versus Circumferential Cerculage wire in treatment of patellar Fractures.
Authors: A. Al â€“Fatlawy Wejdi
Published: January 2024

Fracture of patella comprises approximately 1% of all skeletal injuries. We managed 32 patients with closed transverse patellar fractures in a prospective study during the period between November 2006 and December 2008(with mean follow up one year) at al Sader, al Hakeem and al Manathera hospitals .All cases were treated by open reduction and internal fixation. There were 16 cases randomly fixed by modified tension band and longitudinal Kirschner wires (MTB&LKW) method and 16 randomly fixed by circumferential cerculage wire (CCW) in patients' age (20-50 years). The results were assessed by a Lysholm & Gillquist score. Regarding (MTB&LKW) method, the outcome was excellent in 50%, good in 37, 5 %, and fair in 12,5%case but the outcome was excellent in31,75%,good in25%, fair in 25% and poor in 18,25 % with (CCW) method. We concluded that the (MTB&LKW) fixation method is superior to (CCW) method in that it shortens the average time for union and allowed less fracture displacement than did other method. The aim of the study is to determine whether modified tension band fixation method results in better outcomes compared with those after circumferential Cerculage wire fixation method in the treatment of closed patellar fractures.
Somatization Disorder Among Primary Health Care Centers Patients
Authors: Mohammed Alkhafaji Abdulzahra , Abdulhassan Faris Mohammad
Published: January 2024

Background: Somatization disorder is multiple medically unexplained symptoms of long duration& involve multiple organ systems.Objectives: To study the prevalence of somatization disorder among patients of PHC. Centers and the role of the various sociodemographic factors also demonstrate the presentation & clinical pattern of somatization disorder.Methods: Out of 678 patients who were selected randomly from two of primary health care centers in Diwaniya city over a period from the first of October 2009 to 31th December 2009. These patients were interviewed using the International Diagnostic checklist for ICD-10 somatization disorder.Results: The study reveals that 14.6%of the patients have Somatization Disorder. and it is most common among (46-55) years age group(19.1%), females(19.7%), divorced (27.8%), illiterate(24.3%), low family income(21.2%) & unemployed (17.0%) patients.

Somatization Disorder was least common among age group(15-25) years(4.5%), male(8.1%), married(12%), highly educated (7.3%), high family income(6.7%) & employed(11.8%) patients. The most common presentation of somatization disorder. was pain in limbs, extremities or joints( 81.8%) .Conclusions : Somatization Disorder. is relatively common in PHC. visitors & this represent a big burden on health institutions if remain undiagnosed for long period.
Isolation and Identification of Bacteria from Patients with Transitional Cells Carcinoma of Urinary Bladder
Authors: Hamad Al-Hamadani Adnan , W. Al-Bideri Adnan , M. Al-Janabi Wa'ad
Published: January 2024

This study was conducted to isolate and identify the bacteria associated with tumor cells urinary bladder, in addition to investigate the histopathological changes in the urothelium of the urinary bladder. A total of 130 urine samples were taken and classified into three groups:(36 samples belong to patients with urinary bladder cancer, 64 samples of urinary tract infections(UTIs), and 30 samples as healthy group (control). These samples were collected from both sexes and different ages and lasted a period from January to June 2010 at Al-Diwaniyah Teaching Hospital. The results revealed that 32/36 (88.8%) of urinary bladder cancer samples were positive for bacterial growth, while was 64/64 (100%) for UTIs samples.The common isolated bacteria associated with tumor cells of urinary bladder and UTIs were similar and included six species (Escherichia coli , Staphylococcus aureus, Proteus morganii, P.mirabilis, Pseudomonas aeruginosa, and Klebsiella pneumonia. But the percentage of isolation was varied and the high percentage belonged to Escherichia coli (34.5%), and the lowest was Klebsiella pneumonia (6.2%).
The role of Î²-catenin in tooth development
Authors: Abdul Hussein Hindy Suha
Published: January 2024

Background:The present experimental study was conducted on tooth development during embryogenesis in developing mouse. with main objective to identify the expression and action Î² -Catenin in development of teeth and mophogenesis. Materials and Methods:This study comprised a total of (21) sections were selected during different stages of tooth development (bud, cap and bell stage), (7) sections from each stage in developing mouse. The expression of Beta-Catenin was carried out on 4Î¼m specimen sections using Immuno histochemical staining of Î²-Catenin antibody. The staining demonstrated the expression intensity.Results:Results shows intense nuclear and cytoplasmic staining in inner enamel epithelium, outer enamel epithelium and in adjacent dental papilla and ecto-mesenchymal cells surrounding the tooth germ, that will give rise to a definite dental sac,while the stellate reticulum, shows only moderate cytoplasmic and not nuclear staining.Conclusion: Î²-catenin is highly expressed during tooth development stages due to its role in cell signaling transmission between the enamel knot and the surrounding mesenchymal cells to induce tooth formation and its morphogenesis.
Immunological assessment of hemodialysis patients in Al- Diwaniya and Al-Najaf governorates
Authors: A.Al-Hilaly Hammady , A. Al-Essami Alaa'a , A. Sharara Arafat
Published: January 2024

The present study was carried out to investigate the immunological status of special category of patients who were ongoing Hemodialysis process as they at End-Stage Renal Disease (ESRD).The study group (patients) included were 82 individuals who were regularly attending HD units at AL-Diwaniya Teaching Hospital and AL-Hakeem Teaching Hospital (AL-Najaf AL-Ashraf) / Iraq during the period Nov.2008 - Aug.2009. Another two control groups; the 1st (n=50)who were apparently healthy and the 2nd(n=32) patients with UTI other than ESRD. They all subjected to a questionnaire form regarding many general variables. Blood samples collected and each divided into tow aliquots; the 1st for hematology and the second (serum) for biochemical and serology tests including IFN-Î³ and IL-8 assays using ELISA. The interesting results those of serum IFN-Î³, IL-8(pg/ml) and CRP(mg/ml) among the three study groups; the median concentration of IFN- Î³ in HD patients and renal disease (not failure) was zero , while it was 0.05 in healthy control. However, the only significant difference was between the first and third groups. Interleukin -8 has seem to be more significant different as it has had median concentration of, 24.1, 23.7, and 104.1 in the three groups above , respectively.