bluuebunny/crossref_metadata_2025 huggingface dataset:
Prescribing Inertia or Not? Quantitative Investigation of Loop Diuretics Prescribing after Palliative Care Consultation among Patients with Heart Failure
Authors: Zidong Zhang , William Frick , Leslie Hinyard , Divya S Subramaniam
Published: September 2024

Purpose: Loop Diuretics (LD) are the first-line pharmacotherapy to address Heart Failure (HF)-associated edema and dyspnea. However, LD causes frequent urinary, resulting in inconvenience and possibly undermining the quality of life. While prescription adjustment is an essential part of Palliative Care Consultation (PCC), it remains unclear how PCC affects the deprescribing of diuretics for adults with HF. Methods: We conducted a pre-post analysis of the percentage of HF patients who were prescribed LD in a national Electronic Health Record (EHR) database 12 months before and after the first PCC. The difference in prescription rates between the periods was determined. Adjusted associations of post-PCC LD prescription with pre-PCC LD prescription and patient’s characteristics, insurance, provider type, and clinical factors were quantified. Results: From 2010 to 2018, 5,969 patients with newly diagnosed HF received at least one PCC, among whom 2,539 (42.5%) were prescribed LD before and 1,552 (26.0%) after their first PCC. Despite a decrease in LD prescription rate encompassing the date of PCC, post-PCC LD prescribing was strongly associated with pre-PCC prescribing (aOR[95%CI] 3.2[2.8,3.7]) and varied by age at first PCC, year of HF diagnosis (aOR[95%CI] 2.1[1.9,2.4]) and months from HF diagnosis to first PCC. While our finding demonstrates reduced polypharmacy associated with PCC, the strong association between pre- and post-PCC indicates reverse therapeutic inertia. Future research should investigate the benefits and costs of polypharmacy among specific patient groups to help develop personalized treatment for HF.
An Overview of Familial Hypocalciuric Hypercalcemia
Authors: Can Huzmeli
Published: September 2024

Familial hypocalciuric hypercalcemia (FHH) is one of the rare reasons for hypercalcemia. FHH is an autosomal dominant disease that is inheritable. The most common calcium sensitive receptors (CaSR) develop because of the inactivation of. In addition, they also develop due to the function loss of AP2S1 and GNA11. The FHH sickness is characterized by hypercalcemia, hypocalciuria, the regular or increased level of the parathyroid hormone, and normal renal function. The symptoms of hypercalcemia are usually not observed. It is often diagnosed by calculating the calcium/creatine clearance ratio of a 24-hour urine sample, and then genetically looking at it. FHH is usually a benign disorder, and when symptomatic and rarely complications develop, calcimimetics are used or parathyroidectomy can be performed. In conclusion, FHH is a benign and genetically transmitted, moderate cause of hypercalcemia. It is rare and usually asymptomatic.
Intervensi Pendekatan Chinema Therapy Dalam Meningkatkan Rasa Empati Peserta Didik Di Kelas 4 Reguler C Tmi Al-Amien Prenduan Tahun 2023
Authors: Wahyudi Heri Fadli , Erfany Muhammad Nurullah , Massuhartono Massuhartono
Published: September 2024

Empati adalah reaksi individu yang terdiri dari komponen kognitif dan afektif dari kemampuan untuk memahami perasaan orang lain. Empati dibangun di atas lingkup kesadaran, sehingga semakin terbuka bagi emosi kita sendiri, semakin terampil dalam memahami perasaan orang lain. Subjeknya adalah 26 peserta didik di kelas 4 Reguler C TMI Al-Amien Prenduan. Tujuan penelitian meningkatkan empati peserta didik melalui penggunaan terapi sinema. Penelitian ini menggunakan pendekatan kualitatif dengan jenis penelitian studi kasus. Adapun penelitian ini mengumpulkan data dengan tiga macam cara tehnik yaitu: observasi, wawancara, dan dokumentasi. Berdasarkan hasil penelitian menunjukkan bahwa intervensi pemberian treatment pada peserta didik yang kurang memiliki empati menggunakan film yang di dalamnya terkandung pesan moral akan pentingnya empati sebanyak empat kali pertemuan dalam meningkatkan empati peserta didik. Hal ini ditunjukkan dengan adanya data observasi dan wawancara yang dinyatakan mengalami perubahan sikap peserta didik. sehingga dapat ditafsirkan bahwa penggunaan terapi sinema efektif untuk meningkatkan empati peserta didik di kelas 4 Reguler C
Penggunaan Kartu RFID Dalam Sistem Presensi dan Saklar Hemat Energi Berbasis Internet of Things di Universitas Muhammadiyah Sukabumi
Authors: Kurnia Moh Dzikri
Published: September 2024

Penerapan teknologi Internet of Things (IoT) telah memberikan dampak signifikan pada berbagai bidang, termasuk pendidikan dan lingkungan. Penelitian ini berfokus pada penerapan teknologi Radio-Frequency Identification (RFID) untuk menciptakan sistem kehadiran dan saklar hemat energi berbasis IoT di Universitas Muhammadiyah Sukabumi. Penelitian ini melibatkan mahasiswa dan dosen sebagai subjek penelitian dan metode pengembangan yang digunakan adalah metode Prototype untuk merancang dan menerapkan solusi secara iteratif. Sistem yang dikembangkan menggunakan RFID pada Kartu Tanda Mahasiswa (KTM) untuk pencatatan kehadiran otomatis, sementara saklar hemat energi yang terintegrasi dengan RFID bertugas mengelola konsumsi listrik di ruangan secara efisien. Penelitian ini mencakup analisis hasil implementasi sistem serta umpan balik dari mahasiswa dan dosen untuk menilai tingkat keberhasilan dan efektivitas solusi yang dikembangkan. Hasil temuan menunjukkan adanya peningkatan yang signifikan dalam efisiensi manajemen kehadiran serta penghematan energi yang substansial. Dengan adanya sistem ini Universitas Muhammadiyah Sukabumi dapat mengoptimalkan penggunaan sumber daya dan menciptakan lingkungan yang lebih efisien serta berkelanjutan bagi seluruh civitas akademika
Effect of LDR, NPL, CAR on Return on Asset of Conventional National Commercial Bank in Indonesia
Authors: Sochib Sochib
Published: September 2024

Every effort to increase company profits impacts the prosperity of investors as owners. Profit optimization involves aligning assets, particularly in banking, where key factors influencing profits include the bank's ability to allocate funds as credit and the management's proficiency in handling loans to maintain collectibility and ensure sufficient capital. Loan distribution is measured using the Loan to Deposit Ratio (LDR), while effective credit management is gauged by Non-Performance Loans (NPL). The adequacy of minimum capital provision is assessed by the Capital Adequacy Ratio (CAR). This study aims to demonstrate the influence of LDR, NPL, and CAR on Return on Assets (ROA) during the 2017-2021 period in Indonesian national commercial banks. Purposive sampling selects a representative sample, and linear regression is employed to analyze the variables' impact. The research findings indicate that LDR and NPL have a significant effect on ROA, while CAR does not.
Experimental research and evaluation of mechanical properties of microstructural components of high strenght steels by quasistatic nanoindentation
Authors: Escherová Jana , Majerík Jozef , Barényi Igor , Kohutiar Marcel , Chochlíková Henrieta
Published: September 2024

The article solves the issue of evaluating the mechanical properties of the microstructural components of the C120U, 90MnCrV8 and X82WCrV9-5-2 tool steels. The reason for the choice of steels and their testing was the fact that on these tool steels are high demands and their properties using in industry, such as high strength, toughness, wear resistance, temperature stability, etc. Experimental measurements were performed on the device a Hysitron TI 950 Triboindenter with Triboscan evaluation software, which is part of CEDITEK Laboratories at Faculty of special technology. The Berkovich type was used as a test tip. Chapter 1 describes the research of foreign authors who in their studies dealt with the mechanical properties of selected types of high-strength steels. In chapter 2, the mechanical and chemical properties of the investigated materials, microstructural analysis and used methods are clearly presented. Based on the analysis, the methodologies of the performed experiments are described in sub-chapter 2.4. Achieved results of own experiments are presented in chapter 3. Realized experimental measurements and evaluation of measured data on selected locations of the investigated areas of tested steels using quasistatic nanoindentation are described in chapters 3 and 4.
Influence of PWM techniques on an induction motor powered by three-phase voltage inverter
Authors: Mohamed Chafa , Kamel Messaoudi , Lamri Louze
Published: September 2024

This paper presents a study on the influence of different PWM control techniques for a voltage inverter on an induction motor. In the first step, we implemented the PWM techniques using the Xilinx System Generator tool, which allows implementation on the FPGA board. Then, we compared the different PWM techniques and their effects on the operation of the induction motor. The results obtained showed that the motor reached the nominal speed, with the best results for starting current and torque achieved by the Triplen Injection PWM (THIPWM) technique compared to the other two techniques, enabling good motor performance.
Dynamic economic load dispatch problems in microgrid containing renewable energy sources based ontunicate swarm algorithm
Authors: Larouci Benyekhlef , Boudjella Houari , Si Tayeb Abdelkader , Nour El Islamayad Ahmed
Published: September 2024

Dynamic Economic Load Dispatch (DELD) is a significant problem in microgridincluding renewable energy sources (RESs). The aim of this paper is to minimize the overall cost of the system while ensuring that the power demands of the consumers are met. However, with the added complexity of RESs, conventional optimization techniques may not be able to provide optimal solutions. This is where metaheuristic algorithms come into play, which are optimization techniques inspired by natural phenomena such as biological, nature, and animal behavior. This studycovers a new bio-inspired algorithm called Tunicate Swarm Algorithm (TSA)applied for solving DELD in microgrid with considering the variable power output of RES such as wind and solar energy. The DELD problem should also incorporate various constraints such as power balance and generation limits. Four cases of DELD containing RESs are treated. The obtained resultsare compared to other methods.. The result shows that for the DELD problem, the TSA demonstrate the superiority in term of optimise thegeneration cost compared to other optimization techniques.
Study of PLL less DSGTP System using band-pass filter and APC (active power coefficient) control
Authors: Basu Roy Chowdhury Saptaparna , Maji Atanu , Hossain Sk Rabiul , Kumar Gayen Pritam
Published: September 2024

This paper represents a study on a grid-tied photovoltaic (PV) system connected to a non-linear load. The system includes a PV array, a boost converter, a voltage source inverter (VSI), and a coupling inductor for grid connection. The maximum power point tracking (MPPT) mechanism based on Perturb and Observe (P&O) method which is used to control the duty ratio of the boost converter. Synchronization is achieved through a second-order band-pass filter instead of a Phase Locked Loop (PLL). However, the non-linear load causes poor current quality, leading to a high Total Harmonic Distortion (THD) in the grid current, which may affect the sinusoidal nature of the grid current and other connected loads. To address the harmonics problem, an Active Power Coefficient (APC) control technique is implemented to control the PV inverter gate pulse. The proposed model has been simulated in Matlab/Simulink, and system output parameters are analysed graphically. The simulation results indicate that the proposed approach maintains the total harmonic distortion (THD) of the grid current below 5% even in changing weather conditions, which satisfies the IEEE 519 standard.
A new quasi Z-source embedded network capable of producing DC-side voltage gain even without shoot-through state for efficient operation
Authors: Kumar Gayen Pritam
Published: September 2024

The conventional quasi-z-source inverter (QZSI) is not capable of producing DC-side voltage gain without shoot-through operation. This restricts freedom of control and performance. The decoupled control between modulation index (MI) and duty ratio for producing DC-side voltage gain at MI = 1 is not permitted. In this context, this paper proposes a novel active-switched impedance network. This is capable of producing DC-side voltage gain either in shoot-through mode or in the absence of shoot-through state. In effect, variable DC-side voltage gains are achieved at a fixed value of MI, even at MI = 1 (without the dead-time requirement of the inverter bridge). For low-gain operations (up to 2.5), the DC-side voltage gain is achieved by the proposed active-switched QZSI by restricting the shoot-through duty ratio to a low value (0-0.1). In high-gain (>2.5) operations, the variable-boosting operations of the proposed QZSI are achieved without shoot-through operation (MI = 1) by controlling its active switch. This increases efficiency by discarding the shoot-through state at high gain. The suggested closed-loop control logic of the proposed QZSI is also provided to meet the load voltage. The simulation work is conducted in versatile operating conditions to highlight its diversified performances. The experiments also verify its operations under different conditions.
MAIN STRATIGRAPHIC BOUNDARIES IN THE CENOZOIC OF PRIMORYE AND THEIR MANIFESTATION IN LITHOLOGY AND PALAEOFLORAS
Authors:   Far East Geological Institute, Far eastern branch, Russian academy of sciences, Pavlyutkin B.I. , Chekryzhov I.Yu. ,   Far East Geological Institute, Far eastern branch, Russian academy of sciences, Petrenko T.I. ,   Far East Geological Institute, Far eastern branch, Russian academy of sciences
Published: September 2024

Within the territory of Primorye, key sections are discussed and compared to the boundaries between high-ranking stratigraphic subdivisions, including the boundaries between the Cretaceous and Paleogene, Paleogene and Neogene, Neogene and Quaternary systems, as well as the boundaries between series within the systems. The following boundaries can be considered as the most valid: the Eocene/Oligocene boundary, timed with the transition from the coal-bearing Khasanskaya Formation to the coalless tuff-siltstone Fatashinskaya Formation (Khasan Basin); the Paleogene/Neogene boundary, marked by the change in the lithological type of rocks from coal-bearing Upper Oligocene to tuff-siltstones, tuffs forming the base of the Miocene (Rakovka Basin). The Miocene/Pliocene boundary is proposed to be drawn within the basaltic lava complex with sedimentary rock packets forming the Shufan volcanic plateau at the base of the Kedrovskaya stratum. The Pliocene/Quaternary boundary corresponds to the base of the red-colored "pudding" sequence (Spassk Basin). The Cretaceous-Paleogene and Paleocene-Eocene boundaries cannot be determined with acceptable accuracy due to the lack of relevant sections in the region.
IMPROVEMENT TO THE ZONAL DIATOM SCALE OF THE NEOGENE IN PRIMORYE (RUSSIA)
Authors:   Far East Geological Institute, Far eastern branch, Russian academy of sciences, Pushkar V.S. , Avramenko A.S. ,   Federal Scientific Center of the East Asia Terrestrial Biodiversity Far Eastern Branch of the Russian Academy of Sciences, Cherepanova M.V. ,   Federal Scientific Center of the East Asia Terrestrial Biodiversity Far Eastern Branch of the Russian Academy of Sciences, Likhacheva O.Yu. ,   Far East Geological Institute, Far eastern branch, Russian academy of sciences
Published: September 2024

Comprehensive study of diatoms from some Neogene stratotype sections of southern Primorye (Sineutesovskaya and Novokachalinskaya formations, Shufansky horizon) using light and scanning electron microscopy methods allowed adjustments to be made to the Zonal Diatom Scale of the Neogene in Primorye. Studies have shown the absence of some zone index species in the sediments: Alveolophora bifaria, A. jouseana, A. areolata. As a result, the corresponding subdivisions of the Scale received new names: Alveolophora hachiyaensis-Aulacoseira elliptica zone, Alveolophora khankaica zone, Alveolophora khursevichiae zone. The position of the Shufansky horizon zones has changed: the Aulacoseira praeislandica zone now corresponds to the Early Pliocene, and the Alveolophora tscheremissinovae zone to the Upper Pliocene. According to the International Stratigraphic Chart of the Cenozoic, the age of the upper boundary of the Alveolophora tscheremissinovae zone was revised to 2.58 Ma ago.
Epistemische Einsamkeit – Quelle einer spezifischen Vulnerabilität in der Palliative Care
Authors: Schmieg Hannah Vera , Hoffmann Magdalena , Müller Beat
Published: September 2024

In der Palliative Care sind Sterblichkeit und Vergänglichkeit keine Gegenstände abstrakter Reflexionen, sie erhalten eine ganz konkrete, reale Dimension für die betroffenen Menschen. Das Erleben der Gewissheit des baldigen Sterbens und Nichtmehrseins ist mit Außenstehenden nicht teilbar, wodurch für Sterbende hieraus eine epistemische Einsamkeit erwächst, die wir als Quelle einer spezifischen Vulnerabilität interpretieren. Mit dieser spezifischen, mit epistemischer Einsamkeit assoziierten Vulnerabilität sind für das Behandlungsteam moralische Implikationen verbunden.
Genes of photoperiod sensitivity and early maturity E1-E4: dynamics of soybean growth in different daylength conditions
Authors:   V. N. Karazin Kharkiv National University, Raievska Iryna , Schogolev Andrii ,   V. N. Karazin Kharkiv National University
Published: September 2024

Background. Morphometric indicators are crucial for evaluating the development and productivity of soybeans. They are influenced by genetic and environmental factors. The use of nearly isogenic soybean lines is a convenient model for determining the impact of early maturity genes and daylength on growth indicators. The aim of this study was to determine the influence of different daylengths and early maturity genes on soybean morphometric indicators under conditions of the temperate zone (at the latitude of Kharkiv – 50° N). Materials and Methods. The study involved nearly isogenic soybean lines of the “Clark” cultivar with varying sensitivity to daylength. The research covers the results of field experiments over three seasons using different soybean lines. After reaching the V3 stage, some plants were subjected to short-day conditions for 14 days. Morphological indicators of ten plants per experimental variant were determined: plant height, dry weight, leaf number, and leaf surface area of soybean plants. Morphometric measurements were taken on the day of the beginning of different daylength treatments and on days 7, 14 and 21. The study results are presented as the mean values of the investigated parameters (plant height, dry weight, number of leaves and leaf surface area of soybean plants). Results. It was shown that under long-day conditions, dominant alleles of the E1 and E3 genes increased the dry weight of plants, while the dominant allele E2 increased plant height. The dominant allele E4 had no significant effect on plant height and weight indicators of soybean plants. Plants with dominant alleles of genes E1-E4 under long-day conditions had smaller leaf area compared to lines with recessive alleles of these genes. Conclusions. The obtained results on the relationships between genetic and environmental factors in influencing soybean plant height, weight, and leaf area can be useful in improving soybean yield and selecting cultivars that will be productive in high latitude conditions.
The effect of 2,6-dimethylpyridine N-oxide on cognitive functions and emotional state of rats following ins long-term oral administration
Authors:   L. I. Medved’s Research Center of Preventive Toxicology, Food and Chemical, Ministry of Health, Ukraine (State Enterprise), Vasetska Olesia , Rashkivska Inna ,   L. I. Medved’s Research Center of Preventive Toxicology, Food and Chemical, Ministry of Health, Ukraine (State Enterprise)
Published: September 2024

Background. Global anthropogenic environmental pollution, intensification of production, daily physical, emotional and psychogenic stress on humans, as well as the working environment provoke a variety of diseases, fatigue, and cognitive impairment, etc. This may be attributed to a reduced nonspecific resistance of the health system and the development of stressful conditions. Therefore, one of the focal points of preventive toxicology is the development of agents with adaptogenic properties that would prevent the occurrence of harmful effects under the influence of stressors. The aim of the present study was to examine the effect of 2,6-dimethylpyridine N-oxide on cognitive functions and emotional status of rats following its long-term oral administration. Materials and Methods. The plant growth regulator (PGR) Ivin (2,6-dimethylpyridine N-oxide, 99.9%) was chosen for the study. Adaptogen Eleutherococcus was used as a reference agent. The study was conducted on Wistar Hannover rats divided into 2 cohorts. Each cohort included the following groups: 1 – intact animals, 2 – control (distilled water), 3 and 4 – Ivin at doses of 13.0 and 0.013 mg/kg (1/100 and 1/100000 LD50), respectively, 5 – Eleutherococcus at a dose of 50 mg/kg. Exposure period – 28 days, oral route of administration. The state of the central nervous system was assessed by behavioural reactions in the Morris Water Maze and the Elevated Plus Maze. Results. Ivin at doses of 13 and 0.013 mg/kg increased the ability to learn and to form short- and long-term memory in rats, as evidenced by a decrease in the average time of platform location in the Morris Water Maze test. Ivin at a dose of 0.013 mg/kg significantly increased the number of rearings in closed arms of the Elevated Plus Maze, indicating its anxiolytic effect. The anti-anxiety effect of Ivin needs to be confirmed by additional studies in the Open Field and/or Hole-board tests. The effectiveness of Ivin in terms of the studied parameters was similar or exceeded those of the known adaptogen Eleutherococcus.
Metodologias ativas no ensino da Prótese Parcial Removível durante a COVID-19
Authors: Cosme-Trindade Dúcia Caldas , Muniz Isis de Araújo Ferreira , Campos Débora e Silva , Meira Ingrid Andrade , Perez Luciano Elias da Cruz
Published: September 2024

Este estudo objetiva apresentar a experiência do componente curricular Prótese Parcial Removível (PPR) da Universidade Federal da Paraíba com a implementação de metodologias ativas, como gamificação, sala de aula invertida e case-based learning (CBL), no ensino à distância, visando sedimentar o aprendizado quanto ao planejamento de arcos parcialmente desdentados. As atividades foram realizadas de forma síncrona e assíncrona, utilizando como casos os esquemas bidimensionais e fotografias de arcos parcialmente desdentados, baseando-se no conceito de sala de aula invertida, no qual os alunos apresentavam os casos e os professores atuavam como mediadores nas discussões. Observou-se um grande engajamento e participação ativa dos alunos na construção do seu conhecimento. A inserção dessas metodologias no ensino remoto funcionou como um eixo motivacional para os alunos, fomentando a aprendizagem e estimulando o desenvolvimento de competências no planejamento em PPR previamente ao atendimento clínico.
TOURISM SECTOR ANALYSIS OF ORIGINAL INCOME OF THE GRESIK DISTRICT
Authors: Sri Setiawati Ririt Iriani , Tri Pamudya Mochammad Akbar , Vizandra Ellyzabeth Putri , Habibie Samas Adimisa Mishbah , Islamudin Ardhi
Published: September 2024

In realizing national development, the central government and local governments also have an important role in the success of national development, so the central government imposes decentralization which aims to provide full discretion to the regions in realizing responsible autonomous regions, to regulate and manage the interests of the community in accordance with the conditions and potential possessed by the region. One of the decentralization can be seen from the number of visits, the number of tourist attractions and the number of hotels in the Gresik Regency area.
The research was conducted on the number of visits, the number of tourist attractions and the number of hotels in Gresik Regency. This study uses primary data with secondary data collection techniques. The analysis test was carried out with classical assumptions, hypothesis testing and data processing using SPSS version 25. The results of the data analysis test indicate that simultaneously the number of visits, the number of tourist attractions and the number of hotels have an effect on local revenue. And partially the number of visits, the number of tourist attractions and the number of hotels together have an effect on local revenue.
            The conclusion of this study is that the independent variables, namely the number of visits, the number of tourist objects, and the number of hotels, simultaneously and partially affect the dependent variable, namely local revenue in Gresik Regency.
Peningkatkan Hasil Belajar Matematika Materi Sistem Persamaan Linier Dua Variabel (SPLDV) Melalui Model Pembelajaran Diskusi Kelompok Pada Siswa Kelas VIII B Siswa SMP Negeri 1 Tegalrejo Kabupaten Magelang
Authors: Widihastuti Erna
Published: September 2024

Di dalam pembelajaran matematika salah satu permasalahannya adalah lemahnya kemampuan siswa dalam menerapkan pengetahuan untuk menyelesaikan masalah dalam kehidupan nyata terutama dalam menyelesaikan soal Sistem Persamaan Linier Dua Variabel (SPLDV). Untuk mengatasi masalah tersebut, dilakukan penelitian tindakan kelas (PTK) menggunakan model diskusi kelompok. Tujuan penelitian ini adalah untuk meningkatkan hasil belajar siswa kelas VIII B SMP Negeri 1 Tegalrejo Tahun Pelajaran 2022/2023 menggunakan model pembelajaran diskusi kelompok. Subjek penelitian adalah siswa berjumlah 32 orang, sumber data penelitian diperoleh dari data kualitatif berupa data hasil observasi aktivitas guru dan siswa serta data kuantitatif berupa data tes hasil belajar siswa. Hasil penelitian siklus I diperoleh siswa yang tuntas secara individu sebanyak 15 siswa dengan ketuntasan klasikal sebesar 46,88 %. Sedangkan hasil penelitian siklus II mengalami peningkatan dengan jumlah siswa yang tuntas secara individu sebanyak 28 siswa dengan presentase ketuntasan 87,5 %. Berdasarkan hasil penelitian tersebut, pembelajaran menggunakan model pembelajaran diskusi kelompok dapat meningkatkan hasil belajar siswa kelas VIII B SMP Negeri 1 Tegalrejo Tahun Pelajaran 2022/2023.
Proses Pembelajaran Materi Aksara Jawa Di SMA Negeri 3 Sukoharjo
Authors: Gozeka Putra Okky , Sawitri Sawitri , Eerste Eerste
Published: September 2024

Mata pelajaran Bahasa jawa memuat salah satu materi yaitu aksara jawa. Aksara jawa merupakan warisan leluhur berwujud sastra tulisan. Tujuan Penelitian ini untuk mengetahui proses pembelajaran materi aksara jawa di Sekolah Menengah Atas Negeri 3 Sukoharjo, yang beralamatkan Jalan Jendral Sudirman N0. 197, Gayam, Gabusan, Jombor, Kecamatan Bendosari, Kabupaten Sukoharjo, Jawa Tengah. Penelitian ini menggunakan metode penelitian kualitatif. Metode pengumpulan data yang digunakan dalam penelitian ini menggunakan metode observasi. Hasil penelitian dapat diketahui bahwa bahwa dengan adanya proses pembelajaran materi aksara jawa yang menarik dan seuai dengan kebutuhan. para siswa di SMAN 3 Sukoharjo dapat mengembangkan kemampuan membaca dan menulis aksara jawa.
Pengaruh Penerapan Etnomatematika Pada Permainan Tradisional Engklek Sebagai Media Pembelajaran Matematika Terhadap Hasil Belajar Siswa Kelas V SDN 097361 Serbelawan
Authors: Efendi Ilham , Surya Edy
Published: September 2024

Penelitian ini bertujuan untuk mengetahui pengaruh penerapan etnomatematika pada permainan tradisional engklek sebagai media pembelajaran matematika terhadap hasil belajar siswa kelas V SDN 097361 Serbelawan tahun pelajaran 2022/2023. Jenis penelitian ini adalah penelitian kuantitatif. Hasil penelitian menunjukkan bahwa penerapan etnomatematika pada permainan tradisional engklek sebagai media pembelajaran matematika memiliki pengaruh terhadap hasil belajar siswa kelas V SDN 097361 Serbelawan. Hal ini dibuktikan dengan perubahan jumlah siswa yang tuntas dalam pembelajaran, dimana pada saat pretest hanya 13 siswa atau 44%dari seluruh siswa kelas V yang dinyatakan dengan kategori tuntas sedangkan pada setelah diberikan perlakuan dan diberikan posttest siswa yang dinyatakan tuntas sebanyak 25 siswa atau 86% dariseluruh siswa kelas V yang berumah 29 Siswa.
Upaya Meningkatkan Hasil Belajar Matematika Materi Persamaan Kuadrat Melalui Model Discovery Learning Pada Siswa Kelas IX C SMP Negeri 13 Magelang Tahun Pelajaran 2022/2023
Authors: Jumono Jumono
Published: September 2024

Penelitian ini bertujuan untuk: 1) Mendeskripsikan proses pelaksanaan model  discovery learning dalam meningkatkan hasil belajar matematika materi persamaan kuadrat pada siswa kelas IX C SMP Negeri 13 Magelang. 2) Mendeskripsikan tingkat hasil belajar matematika materi persamaan kuadrat pada subyek setelah pelaksanaan model discovery learning. Penelitian ini merupakan penelitian tindakan kelas, yang terdiri dari dua siklus, setiap siklus terdiiri dari tiga tahapan kegiatan, yaitu; perencanaan, tindakan dan observasi, dan refleksi. Subjek penelitian adalah siswa kelas IX C di SMP Negeri 13 Magelang yang berjumlah 32 siswa. Pengumpulan data dalam penelitian ini menggunakan lembar observasi dan lembar penilaian hasil belajar. Teknik analisis data yang digunakan adalah deskriptif kualitatif dan deskriptif kuantitatif. Berdasarkan hasil penelitian dan pembahasan diperoleh data Peningkatan hasil belajar Persamaan kuadrat pada siswa kelas IX C SMP Negeri 13 Magelang setelah pelaksanaan pembelajaran dengan Discovery Learning pada siklus I secara rata-rata adalah 73,03 dengan prosentase ketuntasan 78,13% setelah dilakukan siklus II secara rata-rata adalah 75,63 dengan prosentase ketuntasan belajar 87,5%.. Hasil tersebut menunjukkan bahwa model Discovery Learning dapat meningkatkan hasil belajar siswa kelas IX C SMP Negeri 13 Magelang tahun pelajaran 2022/2023.
Meningkatkan Hasil Belajar Siswa Dalam Pembelajaran Matematika Dengan Menggunakan Model Pendekatan Matematika Realistik (PMR) Di Kelas V SDN 009 Kebun Tinggi
Authors: Ningsih Fitri
Published: September 2024

Metode mengajar berupa ceramah yang digunakan oleh guru selama ini,dirasakan kurang cocok untuk diterapkan dikelas karena membuat siswa kurang terlibat dalam proses pembelajaran.Tujuan penelitian ini adalah untuk menganalisis apakah penggunaan model PMR dapat meningkatkan hasil belajar siswa kelas V tentang Penjumlahan Pecahan dengan penyebut yang berbeda. Subjek penelitian ini adalah siswa kelas V UPT SDN 009 Kebun Tinggi semester satu tahun pembelajaran 2023/2024 yang berjumlah 9 siswa terdiri dari 7 siswa laki-laki dan 2 siswa perempuan. Keberhasilan penelitian ini diamati berdasarkan ketuntasan belajar siswa yang diperoleh dari nilai tiap siklus perbaikan pembelajaran. Siswa dinyatakan tuntas dalam hasil belajar apabila mencapai nilai 62 sedangkan kelas dinyatakan tuntas apabila terdapat 80% siswa yang mendapatkan nilai 62 atau lebih. Berdasarkan data yang diperoleh pada pra siklus, dari 9 siswa yang mencapai ketuntasan hasil belajar sebanyak 3 siswa (33,3%). Pada siklus I sebanyak 5 siswa (55,5%), sedangkan siklus II sebanyak 8 siswa (88,8%). Dengan melihat persentase ketuntasan siswa pada siklus II yang melebihi 80% atau tepatnya (88,8%) maka kelas tersebut dapat dinyatakan tuntas. Sehingga dapat disimpulkan bahwa hasil belajar siswa kelas V Tentang Penjumlahan Pecahan dengan penyebut yang berbeda pada UPT SDN 009 Kebun Tinggi dinyatakan meningkat. Oleh karena itu, guru disarankan agar dapat mengembangkan pembelajaran dengan menggunakan model pembelajaran model Pendekatan Matematika Realistik (PMR) karena dapat meningkatkan hasil belajar siswa.
Neutrophil syncytia in the peripheral blood of patients with coronavirus infection (COVID-19)
Authors:   Somov Research Institute of Epidemiology and Microbiology, Vladivostok, Somova L.M. , Abramova S.A. ,   Somov Research Institute of Epidemiology and Microbiology, Vladivostok, Drobot E.I. ,   Somov Research Institute of Epidemiology and Microbiology, Vladivostok, Pustovalov E.V. ,   Somov Research Institute of Epidemiology and Microbiology, Vladivostok,   Far Eastern Federal University, Vladivostok, ILyapun I.N. ,   Somov Research Institute of Epidemiology and Microbiology, Vladivostok, Shchelkanov M.Yu. ,   Somov Research Institute of Epidemiology and Microbiology, Vladivostok,   Far Eastern Federal University, Vladivostok,   A.V. Zhirmunsky National Scientific Center of Marine Biology, Far Eastern Branch, Vladivostok
Published: September 2024

Introduction. COVID-19, an infectious disease etiologically related to the coronavirus SARS-CoV-2, manifests with fever, respiratory symptoms, and lymphocytopenia. Pathogenic mechanisms of COVID-19 remain largely unclear. SARS-CoV-2 infection was found to cause the formation of multinucleated syncytia, which dominate in lung tissues and can target lymphocytes, potentially contributing to lymphocytopenia. The formation of these structures is considered to be the result of the fusogenic ability of the SARS-CoV-2 spike-like protein. The aim was to study the morphology and pathogenic significance of intercellular interactions of peripheral blood leukocytes in patients with coronavirus infection caused by SARS-CoV-2. Materials and methods. We studiedblood samples of 30 patients infected with the SARS-CoV-2 virus, who underwent treatment in the Regional Clinical Hospital No. 2, Vladivostok, in 2021–2022. The COVID-19 diagnosis was confirmed using a PCR test. Peripheral blood buffy coat samples fixed in OsO4 were embedded in white resin epoxy (Sigma-Aldrich, USA), and then ultrathin sections were prepared. Results. Against the background of the morphological leukocyte abnormality, in the peripheral blood of patients with COVID-19, neutrophilic syncytia were formed. These syncytia consisted of cells interconnected by cytoplasmic bridges. We distinguished three stages of the neutrophilic syncytium formation, at the first one, cells approaching each other and forming large outgrowths involved in cell docking. The second one was characterized by the formation of a synaptic connection between cells (split contact). At the last stage, outer cell membranes fused completely and the syncytium formed. Conclusion. Based on our analysis we assume that the formation of neutrophil syncytia in the peripheral blood of patients with COVID-19 creates conditions for hematogenous dissemination of SARS-CoV-2 and viremia, generalization of infection and the development of multiorgan pathology. Keywords: blood, leukocytes, neutrophil syncytia, morphology, COVID-19, coronavirus, SARS-CoV-2
Placental and peripheral blood changes in functional morphology and immunology in patients with placenta accreta spectrum
Authors:   Vidnoye Perinatal Center, Vidnoye, Kulikov I.A. , Artemyeva K.A. ,   Avtsyn Research Institute of Human Morphology of FSBSI Petrovsky National Research Centre of Surgery, Moscow, Aleksankin A.P. ,   Avtsyn Research Institute of Human Morphology of FSBSI Petrovsky National Research Centre of Surgery, Moscow, Milyutina E.R. ,   Vidnoye Perinatal Center, Vidnoye, Stepanova I.I. ,   Avtsyn Research Institute of Human Morphology of FSBSI Petrovsky National Research Centre of Surgery, Moscow, Nizyaeva N.V. ,   Avtsyn Research Institute of Human Morphology of FSBSI Petrovsky National Research Centre of Surgery, Moscow, Mikhaleva L.M. ,   Avtsyn Research Institute of Human Morphology of FSBSI Petrovsky National Research Centre of Surgery, Moscow
Published: September 2024

Introduction. Placenta accreta spectrum is an abnormal invasion of villous trophoblast into the myometrium and one of the most severe complications of pregnancy. We aimed to study morphofunctional, molecular, and immunological changes in the placenta and peripheral blood in various types of placenta accreta spectrum.Materials and methods. The study involved 45 pregnant women who underwent ultrasound examination at weeks 35–38. According to the ultrasound data, 15 women had placenta accreta and 15 women developed placenta increta. The comparison group included 15 pregnant women without placenta accreta spectrum with a uterine scar after cesarean section. Histological and immunohistochemical studies were performed on paraffin sections of the placentas. We used mouse antibodies to insulin-like growth factor-binding protein-1, pregnancy-specific β-1 glycoprotein, and human placental lactogen, proteinase 3 and measured them using ELISA. We also studied tumor necrosis factor. Immunophenotyping of peripheral blood lymphocytes was performed using flow cytometry. Results. Рlacenta accreta spectrum is accompanied by increased intensity of IHC staining of placental villi for all the studied markers, in contrast to those in the comparison group. The maximum intensity of insulin-like growth factor-binding protein-1 staining was found in placenta increta. Increased serum concentration of proteinase 3 and placental lactogen (placenta increta) and decreased level of insulin-like growth factor-binding protein-1 were found in placenta accreta spectrum.Conclusion. In placenta accreta spectrum, there is a functional redundancy of placental proteins and an increased pro-inflammatory status. An imbalance between aggressive factors are likely to contribute to pathological villous invasion. Keywords: placenta accreta spectrum, immune status, placental proteins, proteinase 3
A Single-Item Measure of (Non)Essentialist Beliefs About Aging: Reliability, Validity, and Application
Authors: Weiss David , Dobkowitz Elisabeth , Prell Tino , Schönenberger Aline
Published: September 2024

Change is an inherent part of aging, which can be understood through the lens of whether such changes are primarily determined by biological factors, such as genetic inheritance, or whether they are shaped by human experiences and adaptability. This paper introduces a single-item scale for assessing these (non)-essentialist beliefs about aging ([N]EBA-SIS). This measure assesses individuals' perceptions of the aging process on along a continuum line, ranging from "genetically predetermined and immutable" to "malleable and changeable." Two studies (N1 = 164, 54 - 75 years and N2 = 98, 67 - 96 years) provide converging evidence of the validity (convergent, divergent, and test-retest) of the (N)EBA-SIS across various contexts (online and paper pencil studies) and populations (healthy adults and geriatric patients). Results demonstrate that the (N)EBA-SIS has strong reliability and validity, including robust test-retest reliability over a four-month period. Given that (non)essentialist beliefs about aging can be represented on a continuum, they can be effectively captured with a single item. Thus, the current research suggests that the (N)EBA-SIS is a valid, reliable and ready-to-use instrument for measuring the (non)essentialist beliefs about aging.
“Read my lips, not my body”: a thematic analysis of autistic people’s social communication preferences
Authors: Sutherland Holly Elizabeth Anne , Crompton Catherine J , Long Joseph , Fletcher-Watson Sue
Published: September 2024

Differences in socialising and communicating between autistic and non-autistic people are well documented, but primarily from the perspective of non-autistic researchers assuming an autistic social communicative deficit. However, recent challenges suggest it may be more accurate to talk about an autistic social communication ‘style’. This qualitative study attempts to better characterise this style, and to understand how differences between it and a non-autistic communicative style might produce communicative misunderstanding. Eight autistic adults (7 women, 1 nonbinary) took part in an online asynchronous focus group over two weeks. They were asked about their social values, their experiences talking to non-autistic people, positive social interactions, and encouraged to comment and feedback on the contributions of others in the group. Thematic analysis produced five themes: 1) truth and honesty, 2) invisible demands and their impacts, 3) empathy and double empathy, 3) autistic strengths and autistic positives, and 5) the role of autistic community. These findings highlight the ways in which autistic people’s different experiences of (and expectations for) social communication can clash with non-autistic people’s, producing disjunctions in understanding, and emphasise the nuance and complexity of participants’ conceptualisations of autism as difference versus deficit versus strength.
There is Only One Theorem in A-Level Calculus or Reverse A-Level Mathematics: A Pedagogical Toy Model of Reverse Mathematics
Authors: Jackson Andrew
Published: September 2024

This paper examines a toy model of reverse mathematics, which is interesting in its own right but also servesas a pedagogical tool for both reverse mathematics and A-level maths. It may also serve as an introductionto proof for beginning university students using material they are already familiar with. Further, this paperexamines the phenomena of many many theorems being equivalent over a base theory, using an unbiased basetheory; providing evidence for how common this phenomena is.
Time and Nostalgia
Authors: Gkinopoulos Theofilos
Published: September 2024

Time constitutes a prominent tool in political communication and the themes around temporality have become central in politics scholarship. Political rhetorical communication ranges from reflection on countries’ historical pasts to projections to idealized futures for the sake of making the past relevant to the future and ensuring countries’ historical continuity. At the same time, future narratives occupy a prominent space in political discourse, built on promises and guarantees, but at the same time often return back to good old ages. These political communicative struggles between the history and the vision or between the past and the present are often appealing to audience and are often used as criteria for political decision and voting. This entry offers an overview of how different temporalities are used in political communication and the political purposes they may fulfill in politicians’ effort to appeal to their audiences. Furthermore, this entry outlines examples such as populist leadership, where struggles between different temporalities may take place and serve different political purposes. Finally, the entry provides some concluding remarks that can spark off further research interest and avenues for future research in political communication.
Perceptually Degraded Experiences with Nature Are Liked Less but Still Restorative
Authors: Ahmed Huda , Van Hedger Kathryne , Berman Marc , Van Hedger Stephen Charles
Published: September 2024

Interactions with nature can improve attentional functioning and decrease mental fatigue. However, the perceptual quality of the experience might influence how effectively nature can improve these cognitive measures, as perceptual quality has been linked to how much nature sounds are liked, which may in turn influence aspects of psychological restoration. The current study manipulated the perceptual quality of both nature and urban soundscapes to examine how degraded sounds might influence the typically observed cognitive benefits of nature-based interventions. Participants (n = 227) completed a working memory task (N-back) and a self-reported mental fatigue measure before and after listening to one of four sound categories, using a 2 (sound type: unaltered, degraded) x 2 (environment: nature, urban) between-participant design. Participants additionally rated the restorativeness of the sound intervention via the Perceived Restorativeness Scale (PRS). Despite participants liking degraded sounds less and judging them as lower in sound quality, we found comparable restorative effects of unaltered and degraded nature sounds across all measures. However, the nature-related benefits for the PRS were entirely driven by how much participants liked the sounds. In contrast, the cognitive restoration measures showed nature-related benefits even after controlling for sound liking ratings and pre-intervention scores. The findings of this study suggest that nature-based restoration can be observed even when stimuli are degraded and liked less. However, measures that focus on the restorative experience itself (e.g., PRS) appear be more related to stimulus preference than measures assessing participants’ cognitive performance.
From Resting-State Functional Hippocampal Centrality to Functional Outcome: An Extended Neurocognitive Model of Psychosis
Authors: Totzek Jana F. , Shah Jai , Young Alexandra L. , Malla Ashok K. , Joober Ridha , Raucher-Chéné Delphine , Lepage Martin , Lavigne Katie M.
Published: September 2024

Background. We previously proposed a neurocognitive model of psychosis in which reduced morphometric hippocampal-cortical connectivity precedes impaired episodic memory, social cognition, negative symptoms, and functional outcome. We provided support for this model in a patient subtype, and aimed to extend these findings in the modality of resting-state functional MRI to potentially explain the progression for a broader range of patients. Methods. We used a subsample of our previous analysis consisting of 54 patients with first-episode psychosis and 52 controls and applied the machine-learning algorithm Subtype and Stage Inference, which combines clustering and disease progression modeling, to the patient data for rs-functional hippocampal connectivity, episodic memory, social cognition, negative symptoms and functional outcome. Results. We identified three subtypes, with Subtype 0 being unimpaired on the markers, Subtype 1 showing impaired hippocampal connectivity and episodic memory, and Subtype 2 showing impaired memory and a trend for impaired functional outcome. We identified similar progression patterns to the morphometric results in functional MRI data (functional hippocampal dysconnectivity preceded cognition, symptoms, and functioning in one subtype and followed these alterations in another subtype). We further show that the impairments in morphometric and rs-functional hippocampal connectivity do not necessarily overlap in patients, hinting towards an additive effect of each MRI modality in explaining the neurocognitive underpinnings of this model. Conclusion. Our results provide an extension of our previous work and build the foundation for a multimodal neurocognitive model of psychosis, potentially elucidating this important aspect of disease progression in psychosis for a broader range of patients.
Evidence of Black Political Affiliation and Conformity in the US
Authors: Richard Kyler , Booker Jordan Ashton
Published: September 2024

We tested evidence of political conformity among Black adults in the US. We asked whether most Black adults representing the full lifespan and a younger generation of college adults would identify as Democrats; whether personal and ecological factors were related to political affiliation; and whether political affiliation was related with well-being. Findings revealed that most Black adults did identify as Democrat, though there were generational differences. Further, older adults and young women were more likely to identify as Democrats. Political affiliation was not broadly related with well-being, though Independent and Republican college students reported greater friend support during Trump presidency years than during the Biden presidency years. We make a call for improving representation of Black adults in research considering political attitudes and behaviors.