bluuebunny/crossref_metadata_2025 huggingface dataset:
Communicating AI for Architectural and Interior Design: Reinterpreting Traditional Iznik Tile Compositions through AI Software for Contemporary Spaces
Authors: Gür Miray , Çorakbaş Figen Kıvılcım , Atar İmran Satış , Çelik M. Gazihan , Maşat İlayda , Şahin Ceyda
Published: September 2024

Artificial intelligence (AI), which has a strong potential to assist architects in conceptual and visualization stages, has been increasingly used in the field of design and architecture. This study, focusing on the AI tools that generate images from texts and offer innovative solutions to design problems, aims to evaluate the use of AI for the reinterpretation of traditional Iznik tile patterns and colors in the context of architectural design and modern interiors. The methodology consists of four stages, which are the selection of AI tools (Copilot, DALL-E 2, DALL-E 3, Midjourney), the preparation of textual prompts for testing “çini” (tile) expression, testing of the AI tools’ perception of the concepts related to Iznik tile motifs, and the creation of prompt series. The findings of our study provide evidence that current AI tools exhibit distinct features in terms of variety, conceptualization, artistic visualization, and image production, while they are hardly equipped with the necessary conceptual background to communicate with the designers for the interpretation of the traditional Iznik tiles in contemporary architectural design. Specifically, Midjourney, which could produce historically referenced contemporary designs in response to textual expressions, was more successful than other AI tools. DALL-E 2 could not visualize the expressions concerning the placement of the Iznik tile surfaces in interior spaces but was quite inspiring in terms of the images regarding the tile pattern and color. DALL-E 3 and Copilot tools produced similar images in terms of color palette and patterns, whereas DALL-E 3 was better at visualizing spatial data. Our results reveal that AI tools still need to be developed for analyzing traditional patterns, styles, and forms for contemporary design purposes. On the other hand, AI tools can develop innovative approaches, optimize the tile production procedure, and have the potential to accelerate the design process for designers by generating new and diverse ideas.
The Influence of Smart Green Spaces on Environmental Awareness, Social Cohesion, and Life Satisfaction in High-Rise Residential Communities
Authors: Li Yixuan , Wu Yincai , Luo Yiru , Fu Zhiwei , Zhang Shiran
Published: September 2024

Urbanization has driven the growth of high-rise residential areas, creating unique challenges for enhancing residents’ well-being, especially in large metropolitan regions. This study investigated the impact of smart green spaces—green areas integrated with technology to optimize environmental benefits—on environmental awareness, social cohesion, and life satisfaction in these dense urban environments. Utilizing data collected from questionnaires and field interviews in seven representative high-rise residential areas in Guangzhou, China, the structural equation model (SEM) was employed to explore the complex effects of smart green spaces. The findings reveal positive correlations between the presence, accessibility, and technological features of smart green spaces, which contribute to heightened environmental awareness, strengthened social bonds among residents, and increased life satisfaction. These results emphasize the diverse benefits of urban green spaces enhanced by smart technologies, beyond their aesthetic and recreational roles. This study suggests that strategic planning and policy initiatives focused on the development and operation of smart green spaces can substantially improve urban residents’ well-being by fostering environmental consciousness, promoting community interaction, and enhancing the overall quality of life in high-rise residential settings. These insights are crucial for urban planners, policymakers, and community stakeholders, providing a blueprint for leveraging smart green spaces in creating sustainable, resilient, and livable urban environments.
Public’s Visual Preferences Survey Facilitates Community-Based Design and Color Standards Creation
Authors: Najar Karim , Nylander Ola , Woxnerud William
Published: September 2024

According to research, there is a disparity in the aesthetic design preferences of the public and architects. This is especially noticeable in urban areas environments, where there is a wide range of demographic variables and a lack of active public involvement in decision-making. The study included a visual preference survey to evaluate the perception and ranking of two dominant color schemes in local development projects in Stockholm across different age, ethnicity, and gender groups from Sweden. Over 400 people participated in the survey, which used photo-elicitation and a literature review. The objective was to determine the extent of divergence and disparities in the ranking of color schemes. The first dominant color schemes are a group of four analogous colors related to the Natural Color System’s (NSC’s) basic colors. The second is a group of four neutral colors that are related to grayscale colors. The study demonstrates that one could also measure building color schemes using visual preference ranking. Moreover, the research introduced a unique method for city planners to understand diverse ethnic, gender, and age group perceptions of color schemes in current projects, promoting active participation in decision-making and providing valuable insights. These insights can enhance people’s sense of belonging, a prerequisite for social sustainability, and improve the quality and profitability of future projects.
Energy Monitoring and Analysis of a Residential House in China
Authors: Wang Yanzhi , Han Shaotong , Zhang Qiuqi , Sun Jing , Cheng Zhibao , Chen An
Published: September 2024

The energy consumption of residential buildings plays a crucial role in overall energy consumption and environmental sustainability. This paper aims to conduct an energy analysis of a residential house located in China, with a focus on comparing the accuracy of the model, identifying areas for improvement, and proposing energy-efficient solutions. Four sets of temperature sensors were placed to monitor the ambient temperature at which the building is located and the indoor temperature of the residential building during a heating season. The energy consumption of keeping the building running at a low temperature was recorded and compared with the simulation results to verify the accuracy of the model. The monitoring results give the weekly average temperature of each zone on each floor, and the door and window positions, room layouts, and orientations are discussed to analyze the thermal response of the building. In addition, the effect of the heat transfer coefficient of the exterior walls, the heat transfer coefficient of the roof, and the solar heat gain coefficient (SHGC) of the exterior windows on the heating energy consumption of the building are further analyzed through simulations. The results show that, after adding a certain thickness of insulation to the exterior walls and roofs of a building, increasing the thickness of the insulation layer produces little extra energy saving. The use of building windows with high SHGC can effectively reduce building heating energy consumption.
A Two-Stage Genetic Algorithm for Beam–Slab Structure Optimization
Authors: Yang Zhexi , Lu Wei-Zhen
Published: September 2024

Beam–slab structures account for 50–65% of a building’s total dead load and contribute to 20% of the overall cost and CO2 emissions. Despite their importance, conventional beam–slab structural optimization methods often lack search efficiency and accuracy, making them less effective for practical engineering applications. Such limitations arise from the optimization problem involving a complex solution space, particularly when considering components’ arrangement, dimensions, and load transfer paths simultaneously. To address the research gap, this study proposes a novel two-stage genetic algorithm, optimizing beam–slab layout in the first stage and component topological relationships and dimensions in the second stage. Numerical experiments on the prototype case indicate that the algorithm can generate results that meet engineering accuracy requirements within 100 iterations, outperforming comparable algorithms in both efficiency and accuracy. Additionally, this heuristic approach stands out for its independence from prior dataset training and its minimal parameter adjustment requirement, making it highly accessible to engineers without programming expertise. Statistical analysis of the algorithm’s optimization process and case studies demonstrate its robustness and adaptability to various beam–slab structural optimization problems, revealing its significant potential for practical engineering scenarios.
Trends in Cancer Incidence and Mortality in US Adolescents and Young Adults, 2016–2021
Authors: Zhang Li , Muscat Joshua E. , Chinchilli Vernon M. , Behura Chandrika G.
Published: September 2024

(1) Background: The incidence rate of early onset-cancer (<50) has increased since 1995. Among younger people, cancers in AYAs (aged 15–39 y) are often biologically distinct tumors from those treated in the pediatric and older adult population. The current study describes trends in the United States for the most recent years including the first year of the COVID-19 epidemic. We aimed to describe the recent incidence and mortality trends of cancers in AYAs (aged 15–39 y). (2) Methods: We used data from the Surveillance, Epidemiology, and End Results (SEER 22) from 1 January 2016 to 31 December 2021. Age-adjusted incidence and mortality rates were assessed by SEER*Stat 8.4.3 for major cancer types by sex, race/ethnicity, age, and metropolitan/nonmetropolitan status. Time trends of age-adjusted incidence and mortality rates were examined by sex and metropolitan/nonmetropolitan status. (3) Results: Age-adjusted overall cancer incidence and mortality rates were stable during this study period. The age-adjusted incidence rates declined significantly for ependymoma, melanoma, carcinomas of lung, bronchus, and trachea, unspecified malignant neoplasms, and non-Hodgkin’s lymphoma. Significant increases were found for gastrointestinal tract cancers and non-Kaposi sarcomas. The age-adjusted mortality rate decreased for acute myeloid leukemia, melanoma, carcinomas of liver and intrahepatic bile ducts, kidney and, in women, leukemia. For some cancers, rates differed by sex, race, ethnicity, and geography. Monitoring the rates and time trends of AYA cancer emphasizes the distinct health concern for this age group.
Cine-MRI and T1TSE Sequence for Mediastinal Mass
Authors: Grott Matthias , Khan Nabil , Eichhorn Martin E. , Heussel Claus Peter , Winter Hauke , Eichinger Monika
Published: September 2024

Background/Objectives: Contrast-enhanced computed tomography (CT) is the standard radiologic examination for evaluating the extent of mediastinal tumors. If tumor infiltration into the large central thoracic vessels, the pericardium, or the myocardium is suspected, cine magnetic resonance imaging (cine-MRI) can provide additional valuable information. Methods: We conducted a retrospective study of patients with mediastinal tumors who were staged with CT, cine-MRI, and a T1-weighted turbo spin echo (T1TSE) prior to surgical resection. Imaging was re-evaluated regarding tumor infiltration into the pericardium, myocardium, superior vena cava, aorta, pulmonary arteries, and atria and compared with intraoperative findings and postoperative histopathological reports (gold standard). Unclear CT findings were further investigated. Results: Forty-seven patients (29 female and 18 male patients; median age: 58 years) met the inclusion criteria. Cine-MRI was able to predict infiltration of the aorta in 86%, pulmonary arteries in 85%, and atria in 80% of unclear CT cases. Aortic tumor infiltration in unclear CT cases was significantly more often correctly diagnosed with cine-MRI than with T1TSE sequence. Conclusions: Additional cine-MRI is of crucial benefit in unclear CT cases. We recommend performing cine-MRI if infiltration into the large central vessels and atria is suspected. T1TSE sequence is of very limited additional value.
External Validation of Risk Scores for Predicting Venous Thromboembolism in Ambulatory Patients with Lung Cancer
Authors: Yan Ann-Rong , Yip Desmond , Peterson Gregory M. , Samarawickrema Indira , Naunton Mark , Newman Phillip , Mortazavi Reza
Published: September 2024

Background: The purpose of this study was to evaluate the discriminatory capability of the Khorana, PROTECHT, CONKO, and COMPASS-CAT scores in ambulatory patients with lung cancer. Methods: This retrospective cohort study included 591 patients with newly diagnosed lung cancer. A symptomatic or incidental VTE occurred in 108 patients. Results: The Khorana score at a 2-point threshold had a discriminatory capability with an odds ratio (OR) of 1.80 and an AUC of 0.57 for 6 months, and an OR of 1.51 and an AUC of 0.55 for 12 months. The CONKO score at a 2-point threshold had a stronger discriminatory capability for both 6 months and 12 months with ORs of 3.00 and 2.13, and AUCs of 0.63 and 0.59, respectively. Additionally, higher white blood cell counts, higher neutrophil counts, hypoalbuminaemia, and not undergoing lung surgery were related to VTE occurrence (p < 0.05). Conclusions: The Khorana score with the 2-point threshold was validated in ambulatory patients with lung cancer, with the results indicating a decline in its discriminatory capability over time (at 12 months vs. 6 months from diagnosis). The CONKO score at the original 2-point threshold showed a stronger discriminatory capability but further validation with a larger sample size is recommended. The identified predictors should be further investigated in future research.
Novel DNA Repair Inhibitors Targeting XPG to Enhance Cisplatin Therapy in Non-Small Cell Lung Cancer: Insights from In Silico and Cell-Based Studies
Authors: Manguinhas Rita , Serra Patrícia A. , Gil Nuno , Rosell Rafael , Oliveira Nuno G. , Guedes Rita C.
Published: September 2024

NSCLC is marked by low survival and resistance to platinum-based chemotherapy. The XPG endonuclease has emerged as a promising biomarker for predicting the prognosis of cisplatin-treated patients and its downregulation having been reported to increase cisplatin efficacy. This study presents an integrated strategy for identifying small molecule inhibitors of XPG to improve cisplatin therapy in NSCLC. A structure-based virtual screening approach was adopted, including a structural and physicochemical analysis of the protein, and a library of small molecules with reported inhibitory activities was retrieved. This analysis identified Lys84 as a crucial residue for XPG activity by targeting its interaction with DNA. After molecular docking and virtual screening calculations, 61 small molecules were selected as potential XPG inhibitors, acquired from the ChemBridge database and then validated in H1299 cells, a NSCLC cell line exhibiting the highest ERCC5 expression. The MTS assay was performed as a first screening approach to determine whether these potential inhibitors could enhance cisplatin-induced cytotoxicity. Overall, among the eight compounds identified as the most promising, three of them revealed to significantly increase the impact of cisplatin. The inherent cytotoxicity of these compounds was further investigated in a non-tumoral lung cell line (BEAS-2B cells), which resulted in the identification of two non-cytotoxic candidates to be used in combination with cisplatin in order to improve its efficacy in NSCLC therapy.
Photo-Fenton Treatment under UV and Vis Light Reduces Pollution and Toxicity in Water from Madín Dam, Mexico
Authors: Amado-Piña Deysi , Romero Rubi , Salazar Carmona Emmanuel , Ramírez-Serrano Armando , Gómez-Oliván Leobardo Manuel , Elizalde-Velázquez Gustavo , Natividad Reyna
Published: September 2024

Water from Madín Dam in Mexico has been shown to contain a wide variety of pollutants such as drugs, pesticides, personal care products and compounds that are released into the environment as waste from production processes. In this work, the effect of the main process variables on the percentage of total organic carbon (TOC) removal in water samples from the Madín reservoir was studied by applying a photo-Fenton treatment catalyzed with iron-pillared clays. The catalyst was characterized by XRD, N2 physisorption, DRS and XPS. The sampling and characterization of the water from the Madín reservoir was carried out according to Mexican standards. The system for treatment tests was 0.1 L of reaction volume and a controlled temperature of 23–25 °C, and the reaction system was kept under constant stirring. After 4 h of treatment time under UV light, the TOC removal was 90%, and it was 60% under Vis light. The main ROS involved in the photo-Fenton process driven by UVC light were hydroxyl radicals, while hydroperoxyl radicals predominate in the Vis-light-driven process. Evidence of superoxide anion participation was not found. The toxicity of untreated and treated water was assessed on Danio rerio specimens, and it was observed to be reduced after the photo-Fenton treatment.
Investigation into the Fuel Characteristics of Biodiesel Synthesized through the Transesterification of Palm Oil Using a TiO2/CH3ONa Nanocatalyst
Authors: Lin Cherng-Yuan , Tseng Shun-Lien
Published: September 2024

Biodiesel is a renewable and sustainable alternative fuel to petrol-derived diesel. Decreasing the operating costs by improving the catalyst’s characteristics is an effective way to increase the competitiveness of biodiesel in the fuel market. An aqueous solution of sodium methoxide (CH3ONa), which is a traditional alkaline catalyst, was immersed in nanometer-sized particles of titanium dioxide (TiO2) powder to prepare the strong alkaline catalyst TiO2/CH3ONa. The immersion method was used to enhance the transesterification reaction. The mixture of TiO2 and CH3ONa was calcined in a high-temperature furnace in a range between 150 and 450 °C continuously for 4 h. The heterogeneous alkaline catalyst TiO2/CH3ONa was then used to catalyze the strong alkaline transesterification reaction of palm oil with methanol. The highest content of fatty acid methyl esters (FAMEs), which amounted to 95.9%, was produced when the molar ratio of methanol to palm oil was equal to 6, and 3 wt.% TiO2/CH3ONa was used, based on the weight of the palm oil. The FAMEs produced from the above conditions were also found to have the lowest kinematic viscosity of 4.17 mm2/s, an acid value of 0.32 mg KOH/g oil, and a water content of 0.031 wt.%, as well as the highest heating value of 40.02 MJ/kg and cetane index of 50.05. The lower catalyst amount of 1 wt.%, in contrast, resulted in the lowest cetane index of 49.31. The highest distillation temperature of 355 °C was found when 3 wt.% of the catalyst was added to the reactant mixture with a methanol/palm oil molar ratio of 6. The prepared catalyst is considered effective for improving the fuel characteristics of biodiesel.
Targeting the p90RSK/MDM2/p53 Pathway Is Effective in Blocking Tumors with Oncogenic Up-Regulation of the MAPK Pathway Such as Melanoma and Lung Cancer
Authors: Maietta Immacolata , Viscusi Eleonora , Laudati Stefano , Iannaci Giuseppe , D’Antonio Antonio , Melillo Rosa Marina , Motti Maria Letizia , De Falco Valentina
Published: September 2024

In most human tumors, the MAPK pathway is constitutively activated. Since p90RSK is downstream of MAPK, it is often hyperactive and capable of phosphorylating oncogenic substrates. We have previously shown that p90RSK phosphorylates MDM2 at S166, promoting p53 degradation in follicular thyroid carcinomas. Thus, the inhibition of p90RSK restores p53 expression, which in turn inhibits cell proliferation and promotes apoptosis. In the present study, we demonstrated that the p90RSK/MDM2/p53 pathway proved to be an excellent target in the therapy of tumors with MAPK hyperactivation. For this purpose, we selected p53wt melanoma, lung and medullary thyroid carcinoma cell lines with high activation of p90RSK. In these cell lines, we demonstrated that the p90RSK/MDM2/p53 pathway is implicated in the regulation of the cell cycle and apoptosis through p53-dependent transcriptional control of p21 and Bcl-2. Furthermore, with an immunohistochemical evaluation of primary melanomas and lung tumors, which exhibit highly activated p90RSK compared to corresponding normal tissue, we demonstrated that MDM2 stabilization was associated with p90RSK phosphorylation. The results indicate that p90RSK is able to control the proliferative rate and induction of apoptosis through the regulation of p53wt levels by stabilizing MDM2 in selected tumors with constitutively activated MAPKs, making p90RSK a new attractive target for anticancer therapy.
Application of Single Cell Type-Derived Spheroids Generated by Using a Hanging Drop Culture Technique in Various In Vitro Disease Models: A Narrow Review
Authors: Ohguro Hiroshi , Watanabe Megumi , Sato Tatsuya , Nishikiori Nami , Umetsu Araya , Higashide Megumi , Yano Toshiyuki , Suzuki Hiromu , Miyazaki Akihiro , Takada Kohichi , Uhara Hisashi , Furuhashi Masato , Hikage Fumihito
Published: September 2024

Cell culture methods are indispensable strategies for studies in biological sciences and for drug discovery and testing. Most cell cultures have been developed using two-dimensional (2D) culture methods, but three-dimensional (3D) culture techniques enable the establishment of in vitro models that replicate various pathogenic conditions and they provide valuable insights into the pathophysiology of various diseases as well as more precise results in tests for drug efficacy. However, one difficulty in the use of 3D cultures is selection of the appropriate 3D cell culture technique for the study purpose among the various techniques ranging from the simplest single cell type-derived spheroid culture to the more sophisticated organoid cultures. In the simplest single cell type-derived spheroid cultures, there are also various scaffold-assisted methods such as hydrogel-assisted cultures, biofilm-assisted cultures, particle-assisted cultures, and magnet particle-assisted cultures, as well as non-assisted methods, such as static suspension cultures, floating cultures, and hanging drop cultures. Since each method can be differently influenced by various factors such as gravity force, buoyant force, centrifugal force, and magnetic force, in addition to non-physiological scaffolds, each method has its own advantages and disadvantages, and the methods have different suitable applications. We have been focusing on the use of a hanging drop culture method for modeling various non-cancerous and cancerous diseases because this technique is affected only by gravity force and buoyant force and is thus the simplest method among the various single cell type-derived spheroid culture methods. We have found that the biological natures of spheroids generated even by the simplest method of hanging drop cultures are completely different from those of 2D cultured cells. In this review, we focus on the biological aspects of single cell type-derived spheroid culture and its applications in in vitro models for various diseases.
Spectral Algal Fingerprinting and Long Sequencing in Synthetic Algal–Microbial Communities
Authors: Meirkhanova Ayagoz , Marks Sabina , Feja Nicole , Vorobjev Ivan A. , Barteneva Natasha S.
Published: September 2024

Synthetic biology has advanced in creating artificial microbial and algal communities, but technical and evolutionary complexities still pose significant challenges. Traditional methods, like microscopy and pigment analysis, are limited in throughput and resolution. In contrast, advancements in full-spectrum cytometry enabled high-throughput, multidimensional analysis of single cells based on size, complexity, and spectral fingerprints, offering more precision and flexibility than conventional flow cytometry. This study uses full-spectrum cytometry to analyze synthetic algal–microbial communities, enabling rapid species identification and enumeration. The workflow involves recording individual spectral signatures from monocultures, using autofluorescence to capture populations of interest, and creating a spectral library for further analysis. This spectral library was used for the analysis of the synthetic phytoplankton communities, revealing differences in spectral signatures. Moreover, the synthetic consortium experiment monitored algal growth, comparing results from different instruments, highlighting the advantages of the spectral virtual filter system for precise population separation and abundance tracking. By capturing the entire emission spectrum of each cell, this method enhances understanding of algal–microbial community dynamics and responses to environmental stressors. The development of standardized spectral libraries would improve the characterization of algal communities, further advancing synthetic biology and phytoplankton ecology research.
Targeting NETosis in Acute Brain Injury: A Systematic Review of Preclinical and Clinical Evidence
Authors: Savi Marzia , Su Fuhong , Sterchele Elda Diletta , Bogossian Elisa Gouvêa , Demailly Zoé , Baggiani Marta , Casu Giuseppe Stefano , Taccone Fabio Silvio
Published: September 2024

Acute brain injury (ABI) remains one of the leading causes of death and disability world-wide. Its treatment is challenging due to the heterogeneity of the mechanisms involved and the variability among individuals. This systematic review aims at evaluating the impact of anti-histone treatments on outcomes in ABI patients and experimental animals and defining the trend of nucleosome levels in biological samples post injury. We performed a search in Pubmed/Medline and Embase databases for randomized controlled trials and cohort studies involving humans or experimental settings with various causes of ABI. We formulated the search using the PICO method, considering ABI patients or animal models as population (P), comparing pharmacological and non-pharmacological therapy targeting the nucleosome as Intervention (I) to standard of care or no treatment as Control (C). The outcome (O) was mortality or functional outcome in experimental animals and patients affected by ABI undergoing anti-NET treatments. We identified 28 studies from 1246 articles, of which 7 were experimental studies and 21 were human clinical studies. Among these studies, only four assessed the effect of anti-NET therapy on circulating markers. Three of them were preclinical and reported better outcome in the interventional arm compared to the control arm. All the studies observed a significant reduction in circulating NET-derived products. NETosis could be a target for new treatments. Monitoring NET markers in blood and cerebrospinal fluid might predict mortality and long-term outcomes. However, longitudinal studies and randomized controlled trials are warranted to fully evaluate their potential, as current evidence is limited.
Cardiovascular and Metabolic Benefits of Extra Virgin Olive Oil Phenolic Compounds: Mechanistic Insights from In Vivo Studies
Authors: Serreli Gabriele , Boronat Anna , De la Torre Rafael , Rodriguez-Moratò Josè , Deiana Monica
Published: September 2024

Extra virgin olive oil (EVOO) represents a significant source of monounsaturated fatty acids (MUFA) and vitamin E, but it is also considered a functional food, due to the content of peculiar bioactive molecules, such as phenolic compounds, being able to modulate various processes related to aging and the most common metabolic and degenerative diseases. A lot of experimental research has focused on some of these components, but in most cases, the studies were performed in vitro testing compounds at non-physiological concentrations and achieving results that cannot easily be translated in vivo. Recent clinical studies demonstrated that in vivo these compounds are able to regulate physiological functions and prevent several pathological events including metabolic and cardiovascular diseases (CVDs), which represent the main causes of death worldwide. This review aims to sum up the major evidence on the beneficial effects of EVOO phenolic compounds in vivo on these pathologies, describing and evaluating the efficacy in relation to the mechanisms of diseases of the whole phenolic fraction and some of its specific components.
Naturalistic Decision-Making in Intentional Communities: Insights from Youth, Disabled Persons, and Children on Achieving United Nations Sustainable Development Goals for Equality, Peace, and Justice
Authors: Nash Carol
Published: September 2024

The seventeen UN SDGs address critical global challenges. Among them, Goal 10—reducing inequality—and Goal 16—promoting peace, justice, and strong institutions—serve as foundational pillars in democracies, enabling the achievement of all other goals. Children, youth, and persons with disabilities are among those who stand to benefit most from these goals. Insights from the naturalistic decision-making practices of intentional communities, often framed as Contenders or Deviants in social construction theory, could be instrumental in advancing these objectives. This study examines the decision-making practices of three intentional communities representing youth, disabled persons, and children, each fostering a different version of equitable, peaceful, and justice-oriented governance to build strong institutions. The communities studied include a self-producing Korean popular music (K-pop) group representing youth Contenders, a mental health-supporting annual English conference for individuals on the autistic spectrum, and a Canadian alternative education, self-directed public senior elementary and secondary school—both considered Deviant societies in social construction theory, one focusing on disabled persons and the other on children. The historical method assesses the effectiveness of these communities’ preferred practices in achieving Goals 10 and 16. The results offer actionable insights for enhancing equality, peace, and justice while strengthening institutions to realize the full range of UN SDGs in democratic societies.
Synergistic Impacts of Climate Change and Wildfires on Agricultural Sustainability—A Greek Case Study
Authors: Kalogiannidis Stavros , Kalfas Dimitrios , Paschalidou Maria , Chatzitheodoridis Fotios
Published: September 2024

Climate change and wildfire effects have continued to receive great attention in recent times due to the impact they render on the environment and most especially to the field of agriculture. The purpose of this study was to assess the synergistic impacts of climate change and wildfires on agricultural sustainability. This study adopted a cross-sectional survey design based on the quantitative research approach. Data were collected from 340 environmental experts using an online questionnaire. The results showed that extreme weather events such as heavy rains or extreme droughts negatively influence agricultural sustainability in Europe. The results showed that disruptions in ecosystems caused by climate change have a significant positive impact on agricultural sustainability in Europe. Furthermore, forest regeneration after wildfires showed statistically significant positive influence on agricultural sustainability in Europe. The economic impact of fire on crops, cattle, and farms can be estimated. This information can be used to develop and plan agricultural regions near fire-prone areas; choose the best, most cost-effective, and longest-lasting cultivar; and limit fire risk. It is also clear that increased wildfire smoke negatively affects agricultural sustainability.
Research on Drag Reduction for Flexible Skin Inspired by Bionics
Authors: Zhao Pengfei , Li Xin , Luo Zhengjie , Jia Zhenyan , Zhang Kaisheng , Zhang Xiaoping
Published: September 2024

Underwater vehicles typically rely on batteries or other energy sources for operation, where drag reduction can significantly lower energy consumption and extend operational endurance. Inspired by the skin structure of loaches, a flexible structure with scales and mucus pores was designed. First, numerical simulations were conducted. To accurately demonstrate the interaction between the flexible flow field and the fluid flow field and to capture the movement boundaries of the plates, a bidirectional fluid–structure interaction simulation method was used. The numerical results indicate that the flexible structure has a positive effect on drag reduction. In channel experiments, the drag reduction effects of flexible and non-flexible structures were compared. Both showed optimal drag reduction at a water flow speed of 2 m/s and mucus flow speed of 0.1 m/s. The maximum drag reduction rate for the flexible structure was 28.5%, compared to 22.8% for the non-flexible structure. This difference is attributed to the flexible structure altering the flow pattern of the near-wall boundary layer, reducing the velocity gradient of the boundary layer, and increasing its thickness. The findings of this study can provide guidance for future research on flexible surface drag reduction technologies.
Electroless ZnO Deposition on Mg-Al Alloy for Improved Corrosion Resistance to Marine Environments
Authors: Chávez Luis , Veleva Lucien , Castillo-Atoche Andrea
Published: September 2024

Electroless ZnO (≈900 nm) was deposited on the surface of an Mg-Al alloy (AM60) to reduce its degradation in the marine environment. Uncoated and coated ZnO samples were exposed to an SME simulated marine solution for up to 30 days. The AFM and optical images revealed that the corrosion attack on the ZnO-AM60 surface was reduced due to an increase in the surface hydrophobicity of the ZnO coating (contact angle of ≈91.6°). The change in pH to more alkaline values over time was less pronounced for ZnO-AM60 (by ≈13%), whereas the release of Mg2+ ions was reduced by 34 times, attributed to the decrease in active sites on the Mg-matrix provided by the electroless ZnO coating. The OCP (free corrosion potential) of ZnO-AM60 shifted towards less negative values of ≈100 mV, indicating that electroless ZnO may serve as a good barrier for AM60 in a marine environment. The calculated polarization resistance (Rp), based on EIS data, was ≈3 times greater for ZnO-AM60 than that of the uncoated substrate.
Comparative Analysis of Dielectric Behavior under Temperature and UV Radiation Exposure of Insulating Paints for Electrical Equipment Protection—The Necessity of a New Standard?
Authors: Caramitu Alina Ruxandra , Lungu Magdalena Valentina , Ciobanu Romeo Cristian , Aradoaei Mihaela , Lungulescu Eduard-Marius , Marinescu Virgil
Published: September 2024

This paper describes the behavior of some epoxy, acrylic and polyurethane paints used in the protection of electrical equipment under the action of different degradation factors. The degradation factors chosen were temperature and UV radiation. The behavior of the paints under the action of these factors was interpreted by the variation of the tangent of the dielectric loss angle (tg Delta) as well as by FTIR and TG DSC analyses. Tg Delta was considered the reference dielectric characteristic because it best simulates the functionality of the material. The results presented in this paper lead to the conclusion that exposure to thermal cycles and UV radiation is necessary for each paint to give indications about their possibility of use in these conditions. At the same time, the evaluation of thermal stability, even if the exposure is at lower temperatures (than those at which we performed the tests) and/or for shorter periods, is very important for placing the paint in an insulation class. The tests that were the subject of this work provide us with the following information about the three types of paints analyzed: the highest resistance to thermal cycles is presented by S3, followed by S2 and then S1; thermal endurance tests place the polyurethane paint (S3) in insulation class E and the epoxy paint (S1) in insulation class B; and the tests to determine resistance to UV radiation qualify the best paint as acrylic (S2) and the worst as polyurethane (S3). Thus, it can be said that in applications where it is necessary for the protective film to withstand high temperatures, the use of S3 paint (polyurethane) is recommended, and in applications where the films are kept under the influence of UV radiation for a longer time, it is recommended to use coded paint S2 (acrylic). The results presented in this paper lead to the conclusion that the exposure to thermal cycles simulating the use in outdoor conditions and the resilience of paints under UV radiation conditions must be performed for each paint according to its specific use, and the dielectric characteristics must be carefully evaluated because they can reach values under the accepted limit—e.g., thermal stability evaluation—even if the exposure is at lower temperatures and/or for shorter periods. The conclusions of the experimental work must be generalized at different types of electrical insulating paints, and maybe a new standard is necessary to assess the paints’ behavior under usage conditions, with the paints needing to be treated separately from the classical polymeric insulation systems.
Protective Magnetron Sputtering Physical Vapor Deposition Coatings for Space Application
Authors: Kucharska Beata , Bochra Kamil , Wierzchoń Tadeusz , Sobiecki Jerzy Robert
Published: September 2024

In this study, the use of Cr/CrN+CrCN/Cr-C:H, Cr/W-C:H, and Cr/CrN+Ag/Cr-C:H coatings deposited on copper beryllium were investigated. These protective coatings were prepared using the Magnetron Sputtering Physical Vapor Deposition (MSPVD) method. The tests were carried out in order to qualify the outer DLC (Diamond-Like Carbon) layers for use as the protective function and for regulating the thermo-optical properties. The objective of this study was to compare the properties of chromium and chromium nitride-based coatings. The microstructure, architecture, and chemical composition were studied using scanning electron microscopy (SEM), Photo Diode BackScattered Electrons (PDBS), and X-ray dispersion spectroscopy (EDX). The adhesion was evaluated using a scratch test and a peel and pull-off method. The level of protection against the cold welding effect was tested. Thermo-optical, microhardness, and surface electric resistivity tests were performed. It was found that in cases where increased resistance to cold welding is required, DLC2 and DLC3 proved to be the best solutions. An example of such an application is tubular boom antennas, which are stored in a rolled-up form until deployed in space. They are susceptible to cold welding due to vibration during rocket launch and subsequent exposure to high vacuum.
Performance Analysis and Optimization of a Channeled Photovoltaic Thermal System with Fin Absorbers and Combined Bi-Fluid Cooling
Authors: Nasri Hamza , Riahi Jamel , Oueslati Hatem , Taghouti Hichem , Vergura Silvano
Published: September 2024

The conversion efficiency of photovoltaic (PV) cells can be increased by reducing high temperatures with appropriate cooling. Passive cooling systems using air, water, ethylene glycol, and air/water+TiO2 nano bi-fluid froth in the duct channel have been studied, but an overall assessment is essential for its possible application. In the present work, a numerical study is adopted to investigate the impact of the fluid-duct channel type on the electrical and thermal efficiency of the photovoltaic thermal (PVT) collector. Such investigation is achieved by means of a MATLAB R2022b code based on the Runge–Kutta (RK4) method. Four kinds of fluid duct channels are used to optimize the best fluid for improving the overall efficiency of the investigated PVT system. The numerical validation of the proposed model has been made by comparing the numerical and experimental results reported in the literature. The outcomes indicate that varying the duct channel nature affects mainly the electrical and thermal efficiency of the PVT collector. Our results validate that the nature of the fluid affects weakly the electrical efficiency, whereas the thermal efficiency is strongly affected. Accordingly, it is observed that PVT collectors based on nano bi-fluid air/water+TiO2 give the best performance. In this context, an appreciable increase in the overall efficiency of 22% is observed when the water+TiO2 fluid is substituted by air/ water+TiO2 nano bi-fluid. Therefore, these motivating results make the PVT nano bi-fluid efficient and suitable for solar photovoltaic thermal applications since this system exhibits a daily overall efficiency of about 56.96%. The present work proves that controlling the design, cooling technique, and nature of the cooling fluid used is a crucial factor for improving the electrical, thermal, and overall efficiency of the PVT systems.
Vertical Distribution of Culicoides Biting Midges in Temperate Forests
Authors: Bernotienė Rasa , Treinys Rimgaudas , Bukauskaitė Dovilė
Published: September 2024

Culicoides biting midges are small dipterous insects known as biological vectors of arboviruses, protozoa, and filaria parasites worldwide. Many studies on Culicoides focus on trapping them at ground level, without considering the best trap heights for different vector species. This implies that we might overlook insects positioned higher in the canopy. From June to August, we used UV traps to catch Culicoides biting midges at three different heights in three temperate mature forest areas in east Lithuania, Baltic region of Europe. We conducted this study to test the differences in midge numbers, male and female proportions, and female parity at each height. We caught the majority of biting midges (80.6%) at the mid-canopy and high-canopy. A higher number of female Culicoides midges than males was caught, with the proportion of males varying based on height and reaching its lowest point at ground level. No significant difference between the proportion of nulliparous and parous females caught at different height was detected. Culicoides pictipennis and C. festivipennis were the most common species of biting midge we found. They were found in the mid-canopy (86.8%) and the high-canopy (50.0%), respectively. Culicoides kibunensis was next, found at ground level (66.2%), and C. punctatus was found at the high canopy strata (63.0%). Each species’ abundance was seasonal dependent. Information on the vertical distribution of vector species in the temperate forest ecosystem is an important step in understanding patterns of vector borne disease transmission in wildlife.
Update on Patient Self-Testing with Portable and Wearable Devices: Advantages and Limitations
Authors: Lippi Giuseppe , Pighi Laura , Mattiuzzi Camilla
Published: September 2024

Laboratory medicine has undergone a deep and multifaceted revolution in the course of human history, in both organizational and technical terms. Over the past century, there has been a growing recognition of the need to centralize numerous diagnostic activities, often similar or identical but located in different clinical departments, into a common environment (i.e., the medical laboratory service), followed by a progressive centralization of tests from smaller laboratories into larger diagnostic facilities. Nevertheless, the numerous technological advances that emerged at the beginning of the new millennium have helped to create a new testing culture characterized by a countervailing trend of decentralization of some tests closer to patients and caregivers. The forces that have driven this (centripetal) counter-revolution essentially include a few key concepts, namely “home testing”, “portable or even wearable devices” and “remote patient monitoring”. By their very nature, laboratory medical services and remote patient testing/monitoring are not contradictory, but may well coexist, with the choice of one or the other depending on the demographic and clinical characteristics of the patient, the type of analytical procedure and the logistics and local organization of the care system. Therefore, this article aims to provide a general overview of patient self-testing, with a particular focus on portable and wearable (including implantable) devices.
Enhancing Predictive Accuracy for Recurrence-Free Survival in Head and Neck Tumor: A Comparative Study of Weighted Fusion Radiomic Analysis
Authors: Mahdi Mohammed A. , Ahamad Shahanawaj , Saad Sawsan A. , Dafhalla Alaa , Alqushaibi Alawi , Qureshi Rizwan
Published: September 2024

Despite advancements in oncology, predicting recurrence-free survival (RFS) in head and neck (H&N) cancer remains challenging due to the heterogeneity of tumor biology and treatment responses. This study aims to address the research gap in the prognostic efficacy of traditional clinical predictors versus advanced radiomics features and to explore the potential of weighted fusion techniques for enhancing RFS prediction. We utilized clinical data, radiomic features from CT and PET scans, and various weighted fusion algorithms to stratify patients into low- and high-risk groups for RFS. The predictive performance of each model was evaluated using Kaplan–Meier survival analysis, and the significance of differences in RFS rates was assessed using confidence interval (CI) tests. The weighted fusion model with a 90% emphasis on PET features significantly outperformed individual modalities, yielding the highest C-index. Additionally, the incorporation of contextual information by varying peritumoral radii did not substantially improve prediction accuracy. While the clinical model and the radiomics model, individually, did not achieve statistical significance in survival differentiation, the combined feature set showed improved performance. The integration of radiomic features with clinical data through weighted fusion algorithms enhances the predictive accuracy of RFS outcomes in head and neck cancer. Our findings suggest that the utilization of multi-modal data helps in developing more reliable predictive models and underscore the potential of PET imaging in refining prognostic assessments. This study propels the discussion forward, indicating a pivotal step toward the adoption of precision medicine in cancer care.
Tailoring the Diagnostic Pathway for Medical and Surgical Treatment of Uterine Fibroids: A Narrative Review
Authors: Centini Gabriele , Cannoni Alberto , Ginetti Alessandro , Colombi Irene , Giorgi Matteo , Schettini Giorgia , Martire Francesco Giuseppe , Lazzeri Lucia , Zupi Errico
Published: September 2024

Uterine leiomyomas are the most common benign uterine tumors in women and are often asymptomatic, with clinical manifestation occurring in 20–25% of cases. The diagnostic pathway begins with clinical suspicion and includes an ultrasound examination, diagnostic hysteroscopy, and, when deemed necessary, magnetic resonance imaging. The decision-making process should consider the impairment of quality of life due to symptoms, reproductive desire, suspicion of malignancy, and, of course, the woman’s preferences. Despite the absence of a definitive cure, the management of fibroid-related symptoms can benefit from various medical therapies, ranging from symptomatic treatments to the latest hormonal drugs aimed at reducing the clinical impact of fibroids on women’s well-being. When medical therapy is not a definitive solution for a patient, it can be used as a bridge to prepare the patient for surgery. Surgical approaches continue to play a crucial role in the treatment of fibroids, as the gynecologist has the opportunity to choose from various surgical options and tailor the intervention to the patient’s needs. This review aims to summarize the clinical pathway necessary for the diagnostic assessment of a patient with uterine fibromatosis, presenting all available treatment options to address the needs of different types of women.