bluuebunny/crossref_metadata_2025 huggingface dataset:
Les fonds de retournement
Authors: de Germay Nicolas
Published: February 2023

Les investisseurs en retournement financent les entreprises dont les difficultés ne peuvent plus être comblées par les acteurs traditionnels. Il y a trois types de situations, lesquelles sont classées de la moins à la plus risquée : les restructurations financières traitant des déséquilibres du bilan ; le traitement du P&L ( Profit and Loss ‒ Pertes et profits) à la suite d’un accident ou d’un problème conjoncturel ; et la refonte du business model et du P&L. Ces sujets sont traités par deux types d’investisseurs : les fonds, qui gèrent l’argent d’investisseurs institutionnels : ils font preuve d’une certaine passivité et d’une faible implication sur le plan opérationnel ; ils concentrent leurs investissements sur les situations les moins dégradées, les holdings , qui investissent l’argent de leurs associés : au contraire des fonds, ils sont très opérationnels et impliqués et investissent largement même dans les cas les plus critiques. Les investissements en retournement sont des investissements risqués : sur les dix dernières années, seuls environ 10 % des investissements de ce type réalisés en France ont été des succès. Notre opinion est donc qu’il est compliqué d’offrir des retours sur investissement (et une régularité) adaptés au modèle des fonds (LBO). Au regard de sa stratégie, Alandia cherche à prendre le contrôle majoritaire d’entreprises présentant un savoir-faire et dont les leviers permettant leur retournement sont activables par les manageurs de celle-ci (leviers non exogènes), pour les repositionner sur des marchés d’avenir et assurer leur pérennité par la génération de free cash flows .
Inflation, hausse des taux, difficultés de recrutement… : une mobilisation nécessaire des compétences pour faire face à ces problématiques
Authors: Colaert Cédric , Hosni Shafik , Dutheil Édouard , Leboucher Antoine
Published: February 2023

Comment faire face à la crise en tant que chef d’entreprise ? La France a su développer une vraie pratique permettant d’accompagner les entreprises en difficulté et leurs dirigeants. Afin de faire face à de telles situations critiques, il est avant tout crucial de savoir poser le bon diagnostic, grâce à la détection rapide des symptômes. Une fois cette étape passée, il est nécessaire d’identifier les axes de retournement et de négociations avec l’ensemble des parties prenantes (entreprise, créanciers, État, salariés, etc.). Le contexte actuel nécessite de bien appréhender ce processus de traitement des difficultés qui a désormais fait ses preuves dans de nombreux dossiers d’entreprises de toute taille, de la TPE jusqu’au groupe coté.
Les restructurations d’entreprises : comment prévenir les licenciements et accompagner les plans de sauvegarde de l’emploi ?
Authors: Guern Valérie
Published: February 2023

La prévention des licenciements économiques est un enjeu fondamental des politiques de l’emploi mises en œuvre par la délégation générale à l’Emploi et à la Formation professionnelle au sein du ministère du Travail, du Plein emploi et de l’Insertion. L’anticipation et l’accompagnement des mutations économiques sont nécessaires pour maintenir les salariés dans l’emploi et préserver les compétences. À ce titre, plusieurs outils sont mobilisables : l’activité partielle, l’activité partielle de longue durée (APLD) et le FNE-Formation. Lorsque les restructurations s’avèrent inéluctables, l’État est le garant du respect du dialogue social au sein des entreprises qui conduisent des réorganisations et s’assure que les moyens mis en œuvre par ces entreprises favorisent le reclassement des salariés. Dans les situations les plus difficiles, il mobilise des dispositifs spécifiques au bénéfice des salariés dont le licenciement ne peut être évité (contrat de sécurisation professionnelle, prestations grands licenciements, fonds européen d’ajustement à la mondialisation et divers dispositifs sectoriels, comme le fonds automobile.
Critical thinking skills of Chemistry students by integrating design thinking with STEAM-PjBL
Authors: Ananda Lintang Rizkyta , Rahmawati Yuli , Khairi Fauzan
Published: February 2023

This project seeks to foster students' critical thinking abilities through the incorporation of Design Thinking with STEAM-PjBL in a chemistry redox process. 41 grade 10 students from a high school in Rangkasbitung, Banten, Indonesia participated in this study. Learning was facilitated by using a variety of online platforms, including Edmodo, Google Jamboard, and Zoom Meetings. Interviews, observations, journal reflection procedures, and researcher notes were used to gather qualitative data. The five steps of Design Thinking: empathize, define, ideate, prototype, and test, were used to facilitate learning (Plattner, 2010). Critical thinking skills were assessed through the indicators of Framing The Problem, Solution Finding, Self-Regulation, and Reflection, developed by Ucson & Rizona (2018). Based on the categories of Information Search, Creative Interpretation and Reasoning, Reflection, and Self-Regulation, the results demonstrate the development of students' critical thinking abilities to the advanced level. Design Thinking provides a way to more easily and actively create project-based solutions in solving contextual problems related to redox reaction of water pollution in the Ciujung River due to the use of detergent waste. Understanding the relationship of chemical concepts to daily life challenges the application of this approach. To challenge students' learning and help them acquire 21st-century abilities, STEAM-PjBL may be integrated with Design Thinking.
O cumprimento das obrigações fiscais: um estudo sobre a lotaria fiscal e os benefícios fiscais em Portugal
Authors: Cruz José Neves , Sousa Pedro , Wilks Daniela
Published: February 2023

Este estudo analisa o impacto sobre o comportamento de cidadãos portugueses com um nível de escolaridade igual ou superior ao ensino secundário, relativamente a duas medidas de política fiscal – lotaria fiscal e benefícios fiscais – associadas ao programa “e-fatura” e implementadas com vista a incentivar o cumprimento voluntário das obrigações fiscais. As análises quantitativa e qualitativa dos dados recolhidos em inquérito por questionário permitem concluir que as recompensas financeiras devem ser consideradas nas políticas fiscais que pretendam maximizar a cooperação dos cidadãos na redução da evasão fiscal e que são complementares das políticas de controlo e sancionamento da evasão fiscal.
Novel Carbidopa Functionalised Silver Nanoparticles a Selective Detection for Lead and Levodopa
Authors: Popat Pooja R. , Nayee Kinjal , Patel Madhya , Patel Ankit P. , Patel Ruchita J. , Patel Viral A. , Makwana Bharat A.
Published: February 2023

Novel approaches to engineer nanoparticles with desired chemical characteristics open new opportunities to utilize such materials for assorted applications. In this context, various methods have been developed to prepare metal nanoparticles. In the present work, we report a single-step synthesis method to prepare silver nanoparticles by using Carbidopa which is useful in treating Parkinson's disease to increase the dopamine level of the brain. Here we used the Carbidopa drug as a capping agent. Nanoparticles were characterized by Uv-Visible spectroscopy, Particle size Analyzer (PSA), dynamic light scattering (DLS), Powder X-ray Diffractometry (XRD), Fourier Transform Infrared Spectroscopy (FTIR) and Transmission electron microscopy (TEM). Then amino acid detection study was performed with all 24 amino acids, which provides the successful data for sensing the amino acid L-dopa. These prepared nanoparticles were further applied for metal analyte studies which reveal that lead can be sensed successfully by using these nanoparticles. Nanoparticle also shows radical scavenging activity against 2,2-diphenyl-1-picrylhydrazyl (DPPH).
In Vitro Evaluation of Antibacterial Properties of Biogenically Synthesized Zinc Oxide Nanoparticles on Pathogenic Paddy Bacteria
Authors: Abd Rahman Rafidah , Chia Chin Hua , Masdor Noor Azlina
Published: February 2023

Zinc oxide nanoparticles (ZnO-NP) were successfully synthesized from aloe vera extract and zinc sulphate as zinc precursor. Characterizations of the ZnO-NP were performed using UV–Vis spectrophotometer, XRD, FESEM and TEM analysis. The absorption peak from UV–Vis was at 380 nm while the XRD diagram displays high purity ZnO-NP. FESEM and TEM analysis showed agglomerated particles with a wide size distribution range. Polymerase chain reaction (PCR) analysis of Xanthomonas oryzae pv. oryzae (Xoo) pathotype 0.0 generated a product with the size of 230 bp similar to in silico PCR results, verifying the pathotype on molecular level. Subsequently, the antimicrobial activities of the ZnO-NP against Xoo pathotype 0.0 were assessed. Xoo (108 cfu/ml) were grown in LB broth supplemented with various concentrations of ZnO-NP. Collection of samples were done at 24 hours, 48 hours and 72 hours of incubation, grown on LB agar and observed for bacterial growth. Colony forming unit (cfu/ml) values revealed the number of viable cells decreased with high concentrations of ZnO-NP whereas minimal inhibition was observed at lower ZnO-NP concentrations. At lower bacteria cfu/ml (103 cfu/ml), it was found that at 24 hours incubation, ZnO-NP gave comparable antibacterial effects to commercial ZnO-NP and commercial non-nanoZnO after exposure for 1 hour. However, the antimicrobial effects decreased after 48 hours. It was also noted that the ZnO-NP provide better suppression of bacterial growth at lower bacterial concentration.
Synthetic and Natural Polymeric Drug Delivery Systems - A Comprehensive Overview of Polycaprolactone and Glucan Particles
Authors: Bernardi Natalia , Jesus Sandra , Borges Olga
Published: February 2023

The small size and large surface area of nano and microparticles are interesting properties for drug delivery, hypothetically capable of overcoming some limitations of conventional therapeutic medicine and diagnostic agents. Although their features are highly influenced by the polymer characteristics, these particles are known for encapsulating high amounts of drugs, improving their stability and bioavailability and enabling different administration routes. Among synthetic polymers, polycaprolactone (PCL) nanoparticles are widely studied in drug delivery due to the polymer excellent biocompatibility and degradability and for its ability to blend with other polymers. On its turn, among natural polymers, glucan has been emerging as a promising candidate for drug delivery particularly due to structure forming abilities and its immunomodulatory effects. Under the safe-by-design approach for the development of polymeric particles, this review encloses a comprehensive summary of production methods, physicochemical characteristics and immunotoxicity profiles of PCL and glucan particles developed for drug delivery.
The Evaluation of Complementary Metal-Oxide Semiconductor (CMOS) in Smartphone to Test X-Ray Tube Radiation Leakage
Authors: Yoshandi Tengku Mohammad , Zaky Abdul , Patrian Adit
Published: February 2023

Radiation detection method has been developed through years. It started from the complex module tools to simple handheld instrument. Recently, the more ease method has been developed with the help of smartphone application. To detect radiation using smartphone usually required the external tools connected to the phone as detector, but there is one application that did not. This application only required complementary metal-oxide semiconductor (CMOS) part of camera. The application is a game changer in radiation protection because nowadays smartphone is in everyone’s pocket. The application needs to be tested to ensure its effectiveness to detect radiation. The application has been tested by the previous research and it is effective to detect radiation. In this research, CMOS will be tested to detect radiation leakage of x-ray tube. The aim of this research is to find the effectiveness of CMOS in smartphone for radiation leakage detection of x-ray tube. The finding will help the radiation worker detect leakage radiation of x-ray tube using smartphone in case of the absences of surveymeter in the facility. The radiation from x-ray machine were detected and measured three times by Iphone 6s, Xs, and 11 using RadioactivityCounter. To ensure there was a leakage, surveymeter is used as a comparative modul. The data obtained from the experiment was analyzed using t-test. The result show that percentage error of Iphone 6s, Xs, and 11 Consecutively were 93.4%, 98.2%, and 98.9%. which mean CMOS in these said phone could detect and measured radiation ineffectively. This due to the low leaked intensity x-ray that came from x-ray machine. From the T-test anaysis found that only Iphone 11 had linear comparison to surveymeter
Physical activity patterns of university students during the COVID-19 pandemic
Authors: Amekran Youssra , El Hangouche Abdelkader Jalil
Published: February 2023

BACKGROUND:

Coronavirus disease (COVID-19) and resulting restrictions have impacted populations’ lifestyles and posed a challenge regarding their behaviors, including physical activity (PA). This study aimed to evaluate PA patterns of university students during the COVID-19 outbreak. We also analyzed the association of participants’ characteristics, including their level of anxiety, under the pandemic conditions, with adherence to the world health organization (WHO) recommendations for PA.

MATERIALS AND METHODS:

This cross-sectional study comprised 717 Moroccan university students recruited during the COVID-19 pandemic. The Global Physical Activity Questionnaire (GPAQ V.2) was used to evaluate PA. Data on sociodemographic characteristics and anxiety levels were also collected. Anxiety was assessed using State-Trait Anxiety Inventory (STAI). Descriptive and inferential statistical analysis was carried out. The association between participants’ characteristics and PA was studied using regression models.

RESULTS:

Of all participants, 33.2% did not achieve the recommended levels of PA. The daily median (25th–75th percentile) time spent in PA was 34.3 min (12.7–98.6), whereas the median time of sedentariness was 10 h per day (6–14). Multivariate analysis showed that female sex (OR = 0.63; 95% CI: 0.44–0.90; P < 0.05) and high level of state anxiety (OR = 0.43; 95% CI: 0.20–0.92; P < 0.05) were negatively associated with the achievement of the WHO recommended PA.

CONCLUSION:

The reported PA patterns of university students during the current outbreak should be taken into account and evoke the necessity of encouraging this population to adhere to the recommended PA levels. Targeting state anxiety related to the conditions we are facing may have a promising effect on the promotion of PA.
Identification of the factors related to the clinical knowledge sharing
Authors: Mazaheri Elaheh , Samouei Rahele , Alavi Mousa , Kelishadi Roya , Ashrafi-rizi Hasan
Published: February 2023

Today, the ability of the organizations to successfully knowledge management and sharing can help them in better performance. Effective knowledge sharing (KS) in the clinical context provides better clinical decisions and improves the quality of care services. This systematic review will be conducted to identify the factors related to the clinical KS (CKS). This systematic literature review will be conducted to search the published documents about the affecting factors on the (clinical) KS. To this end, PubMed, Scopus, Web of Science, ProQuest, Cochrane, Embase, SID, Magiran, IranDoc, and ISC will be thoroughly assessed with considered keywords and search strategy. No time limit will be considered and all relevant documents published will be evaluated until the start date of the search. To the best of our knowledge, no systematic review study has been conducted on the factors related to CKS and our research will try to comprehensively extract the effective factors in this topic. Identifying the factors affecting CKS will lead to transparency in the exchange and interpretation of clinical knowledge in clinical care delivery and making the best clinical decisions as well as improving the quality of clinical care. It will also provide a condition to facilitate the delivery of more effective clinical education for policymakers in the field of clinical education.
Explaining medical students’ perceptions of asynchronous virtual education in the COVID-19 pandemic
Authors: Sodeify Roghieh , Habibpour Zeinab , Akbarbegloo Masoumeh
Published: February 2023

INTRODUCTION:

With the unintended closure of classrooms following the outbreak of COVID-19, the virtual education method is used as an alternative to face-to-face education. Virtual education is one of the important factors in promoting the learning of medical students and has many benefits such as increasing the ability of critical thinking, problem-solving skills, and self-directed learning. However, critically examining students’ perceptions of e-learning can help improve quality and better planning.

MATERIALS AND METHODS:

This research was a qualitative study. Twelve students were enrolled in the study based on purposive sampling. Data were collected using in-depth semi-structured interviews in 2020. All interviews were recorded and then transcribed and analyzed using a continuous comparison and conventional content analysis approach.

RESULTS:

Data analysis revealed four main themes and ten subthemes. The main themes included “student concern,” “teacher barriers,” “technology weakness,” and “asynchronous virtual learning flexibility.”

CONCLUSION:

Asynchronous e-learning in the COVID-19 outbreak had its advantages and disadvantages. By analyzing students’ perceptions in this field, some better designs and planning can be done to increase the quality of education.
Effect of spiritual intelligence training on nurses’ skills for communicating with patients – an experimental study
Authors: Arad Mansour , Alilu Leyla , Habibzadeh Hosein , Khalkhali Hamidreza , Goli Rasoul
Published: February 2023

BACKGROUND:

Since poor communication with the patient has a negative impact on the quality of nursing care, taking the necessary measures to strengthen the relationship with the patient seems necessary. This study was conducted to determine the effect of spiritual intelligence training on nurses’ skills for communicating with patients.

MATERIALS AND METHODS:

This experimental study with the control group and the pretest-posttest design was conducted on 70 nurses working in Imam Khomeini Hospital, Mahabad, in 2019. Randomized stratified sampling was used to recruit participants. Then, participants were randomly assigned to the two groups of control and intervention. The demographic information form and the patient-nurse communication skill questionnaire were used to collect the data. For the intervention group, 7 spiritual intelligence training sessions were held as a workshop in 2 months. Two weeks and a month after the intervention, both groups completed the questionnaires. Data were analyzed with the SPSS software version 17.0.

RESULTS:

The findings showed that the mean communication skill scores in the intervention group before training were 44.71 ± 7.62, which significantly increased to 66.22 ± 8.43 2 weeks after training. Bonferroni multiple comparisons showed the mean communication skill scores significantly increased before, 2 weeks later and in the follow-up phase in the intervention group (P < 0.001).

CONCLUSION:

Spiritual intelligence training is effective in improving the communication skills of nurses. It is recommended that the prepared content can be provided to in-service training units; consequently, nurses can improve their communication skills by individual and group learning.
Identifying the themes of medical tourism business in Iran
Authors: Badrabadi Nafiseh Karimi , Tourani Sogand , Karimi Asef
Published: February 2023

BACKGROUND:

Nowadays, medical tourism reports impressive growth in terms of number of persons, income, and number of countries involved in cross-border flows. It refers to people traveling abroad (from home to a target country) to obtain medical treatment. The present study aimed to identify the themes and codes of the medical tourism business in Iran.

MATERIALS AND METHODS:

We searched international databases (such as PubMed, Scopus, Embase, and Web of Science) and Iranian bibliography thesaurus and repositories (namely, Scientific Information Database and Magiran) using keywords such as medical tourism, international medical travel, and medical tourism business in the English and Persian literature, published between January 2000 and December 2019, identified with no restriction on the type of the studies. The data were analyzed based on the content analysis method.

RESULTS:

Out of 1054 articles, 14 were finally selected. In the end, eight themes of the medical tourism business including competitive pricing, safety and security, information and communication technology, labor market and human resources, structure management, leading the way in medical tourism, infrastructure, and exchange with the international world were identified which on the whole contain 45 codes. Most of the articles were quantitative. Four of the themes (competitive price, labor market and human resources, structure management, and infrastructure) were most frequent and of the highest importance.

CONCLUSION:

The themes and codes identified in this study helps companies and individuals who want to work in the field of medical tourism. According to this study, all 8 themes and 45 codes are of high value, but still, some themes are of higher value than others and special attention should be paid to them.
Do mothers who meet the minimum standard of antenatal visits have better knowledge? A study from Indonesia
Authors: Anis Wahyul , Amalia Rize Budi , Dewi Erni Rosita
Published: February 2023

BACKGROUND:

Maternal knowledge is one of the indirect causes of maternal mortality in Indonesia. Maternal knowledge that mothers must possess includes knowledge about pregnancy, childbirth, and postpartum. Maternal knowledge should be provided during pregnancy. The aim of this study is to identify maternal knowledge in postpartum women who have a history of the frequency of pregnancy visits according to the minimum standard.

MATERIALS AND METHODS:

A descriptive quantitative design was performed by assessing maternal knowledge to postpartum mothers using an online questionnaire which conducted in 2020 at two public health centers of Surabaya, Indonesia. A sample of this research involved postpartum mothers who completed inclusion criteria, namely physiological postpartum mothers and had regular pregnancy at least 6 antenatal care (ANC) visits. In contrast, the exclusion criteria were postpartum mothers who were not included in the target areas of research. It uses random sampling techniques and performs an analysis using descriptive statistics.

RESULTS:

Three research questions showed a large percentage of wrong answers, namely preparation to face complications (64%), contraceptive methods in breastfeeding mothers (50%) and the first time using contraception during childbirth (42%). Meanwhile, all the correct results (100%) are exclusive breastfeeding and supplementary feeding for babies.

CONCLUSION:

Completing minimal standards of ANC visits cannot ensure adequate maternal knowledge, particularly crucial health information that influences maternal and neonatal health status.
COVID-19 vaccine hesitancy and influence of professional medical guidance
Authors: Nair Govind , Venkatesan Kirthika , Nair Arjun , Firoz Irene N. , Haroon Nisha Nigil
Published: February 2023

BACKGROUND:

Vaccine hesitancy presents a major challenge during the COVID-19 pandemic. It is crucial to address the factors contributing to vaccine hesitancy necessary to control the associated morbidity and mortality. This study aimed to investigate the impact of professional medical guidance on the likelihood of receiving the COVID-19 vaccine in immigrants of USA and Canada.

MATERIALS AND METHODS:

A total of 92 immigrants in the USA and Canada who predominantly spoke Malayalam were recruited using social media platforms. An online survey was administered investigating participants’ confidence in receiving the COVID-19 vaccine. Following, a short webinar was conducted by a medical professional explaining the efficacy and safety of the vaccine. A postwebinar survey was immediately given assessing the confidence and likelihood of receiving the vaccine. SPSS was used to generate descriptive statistics and Pearson Chi-square analysis where appropriate.

RESULTS:

Results revealed that participants who attended the webinar reported greater confidence in receiving the COVID-19 vaccine. There was a statistically significant difference between pre- and postwebinar confidence scores for the COVID-19 vaccine, χ2 (12, n = 80) = 43.34, P < 0.01.

CONCLUSION:

Results from the current study demonstrate the successful delivery of professional medical guidance to the general public through online small-group sessions to help address the misconceptions surrounding the COVID-19 vaccine and combat vaccine hesitancy among vulnerable populations. Future studies should focus on interventions addressing vaccine hesitancy in larger and diverse populations and analyze other barriers to vaccination.
Components of curriculum supervision regarding the accountability of universities of medical sciences
Authors: Avizhgan Maryam , Yamani Nikoo , Omid Athar , Shahidi Shahrzad
Published: February 2023

BACKGROUND:

This study was conducted on accountability, aiming to design components for monitoring the curricula of universities of medical sciences.

MATERIALS AND METHODS:

This study was a developmental one, conducted in Isfahan University of Medical Sciences with the document and literature review, a focus group, and a survey from 2018 to 2020. The first version of the components was designed by the library research and content analysis method. Following developing the initial tool, its validity was evaluated with a focus group, and the questionnaire was prepared according to face and content validity.

RESULTS:

In this study, 73 components were designed in eight domains for curriculum supervision, including requirements (12), needs and goals (6), content (10), teaching–learning strategies (10), educational materials and resources (5), educational time (2), educational setting (10), and evaluation (18).

CONCLUSION:

The components of curriculum supervision were designed due to their importance in the evolution and innovation of medical sciences, particularly accountability in the education system, and lack of relevant research. With these components, the current and optimal status of curricula can be determined in universities.
Understanding the rationales behind childbearing
Authors: Moeini Babak , Erfani Amir , Barati Majid , Doosti-Irani Amin , Hosseini Hatam , Soheylizad Mokhtar
Published: February 2023

BACKGROUND:

Childbearing is the most important determinant of population fluctuations and its studies are more important than other population phenomena. Many factors are associated with childbearing, but individual factors associated with it have been less studied in a specific framework. The present study aimed to explore and identify the factors related to childbearing based on extended theory of planned behavior (ETPB).

MATERIALS AND METHODS:

This qualitative study was conducted among married women <35 years of age and married men whose spouses were under 35 years of age and lived in the City of Hamadan, Iran, in 2019. The data were collected by semistructured and face-to-face in-depth interviews and continued until the data saturation was reached. Overall, 15 interviews were conducted with 17 people. The data were analyzed, using a directed content analysis approach.

RESULTS:

The data analysis resulted in the extraction of 28 main codes, 9 subcategories, and 4 themes, which were correspond to constructs of the theory, consisting of attitudes, subjective norms, perceived behavioral control, and social support in the field of childbearing. The main predictors were attitude toward childbearing and perceived control.

CONCLUSION:

The findings of this study showed that ETPB has a potential to explain the intention and behavior of childbearing. The ETPB makes it possible to understand many of the factors associated with childbearing. The results of this study could be the basis for designing appropriate data collection instrument in quantitative studies and vast surveys.
Use of Repurposed Drugs in COVID-19 Pandemic
Authors: Kapoor Suraj
Published: February 2023

Traditional drug development and discovery have not kept speed with warnings from emerging and re-emerging diseases such as Zika, Nipah, Ebola virus, MERS-CoV, and more newly the pandemic of COVID-19. The new drug discovery has a limitation of high attrition rates, substantial costs, and longer duration for discovery, so repurposing old drugs to treat the diseases becomes a popular and feasible proposition. In contrast, repurposed drugs may be beneficial for patients in a time of pandemics when the natural history of the disease remains unclear. It may be beneficial for the manufacturers as well to generate additional revenues. The use of repurposed drugs in primary care saves money as well as time, particularly important in pandemic times, which can be a cost-effective measure in the public health aspect. Review of literature was carried out about the repurposed drugs used in the COVID-19 pandemic using health bulletins, official handles of health ministries, WHO, published literature, etc. The use of repurposed drugs is beneficial, particularly in pandemic and rare diseases, but their use should be taken with due caution and thorough evaluation. Important public health aspect in primary care includes avoidance of unnecessary hoarding of such drugs. International collaboration in assessing the effectiveness of repurposed drugs is suggested.
Studying the Association between Cigarette Smoking and Serum Copper, Zinc, and Magnesium Concentrations
Authors: Mohammed Asmaa Mahmoud , Hashish Adel F , El-Saeed Gamila S.
Published: February 2023

Background and Objectives:

Tobacco smoking causes damages almost for every organ in the body. Based on the literature review, the relationship between smoking, including nicotine dependence, and the serum zinc (Zn), copper (Cu), magnesium (Mg) status has not been studied sufficiently. The aim of the present study was to determine the relationship of cigarette smoking, including the nicotine dependence state of the smokers, with serum Cu, Zn, and Mg concentrations.

Subjects and Methods:

Overall, 41 active smokers and 44 nonsmokers were investigated for serum Cu, Zn, and Mg concentrations; in addition to urinary cotinine/creatinine ratio. The eight-item Fagerstrom test for nicotine dependence (FTND) questionnaire has been used to determine the nicotine dependence status of the smokers.

Results:

A significant hypozincemia has been detected in 34.1% of the smokers versus 9.1% of nonsmokers, with a five-fold higher risk than nonsmokers. Moreover, a significant hypomagnesemia has been detected in 24.4% of the smokers, with 6.7 fold higher risk than the nonsmokers. The serum Cu concentrations of the smokers were significantly higher (102.4 ± 17.5 μg/dl) than the nonsmokers (70.7 ± 17.1 μg/dl), (P < 0.0001). Each 1 year decrease in the initial age of starting smoking was associated with an increase in the serum Cu concentration by 0.016 μg/dl. Each increase in the serum Cu concentration by 1 μg/dl was associated with a decrease in the serum Zn and Mg concentrations by 0.4 μg/dl and 4 μg/dl, respectively.

Conclusion:

Cigarette smoking is a significant risk factor for hypozincemia, hypomagnesemia, and high Cu concentrations regardless of the nicotine dependence status of the smokers. Early management of hypozincemia may be a preventive measure to decrease the incidence of the oxidative stress-induced diseases.
On the possibility of rogue wave generation based on the dynamics of modified Burridge-Knopoff model of earthquake fault
Authors: Nfor Nkeh Oma , Ndoh Ndikum Eric , Tingue Marceline Motchongom , Nfor Vivian Ndfutu
Published: February 2023

In this study we propose a modified Burridge‐Knopoff model of earthquake fault, in which two tectonic plates are strongly coupled by nonlinear springs. By minimizing the effects of the veloci‐ ty‐weakening stick‐slip friction force between the masses and the moving surface, and in the limit of low amplitude oscillations; the system exhibits both stick‐slip and damped oscillatory motions as the values of some parameters are varied. Such motions usually characterize the dynamics of an earthquake fault, even though it is not always felt because of the low amplitude of vibrations. However when enough stress builds up in the subduction zones to overcome the frictional forces between tectonic plates, the oceanic rocks suddenly slip and there is violent release of energy at the epicentre. This outburst of energy simply signifies the generation of a very large amplitude and localized nonlinear wave. Such wave profile exactly fits the Peregrine solution of the damped/ forced nonlinear Schrodinger amplitude equation, derived from the modified one‐dimensional Burridge‐Knopoff equation of motion. In the regime of minimal or no frictional forces, these mon‐ ster waves suddenly appear and disappear without traces as shown by the numerical investigations. Our results strongly suggest that rogue waves emanates from the dynamics of nonlinearly coupled tectonic plates in subduction zones. This is further complemented by the fact that these giant waves were initially observed in Pacific and Atlantic oceans, which play hosts to the world’s largest oceanic subduction zones.
Parkinson’s Disease Prediction Using Machine Learning
Authors: P Y Mallikarjun , Singh Nitesh Kumar , Bhavana Siddavatam , Swathi Sompalli , Singh Vikas
Published: February 2023

A neurological condition of the brain is Parkinson's disease. It causes the body to shake, the hands to shake, and it makes the body stiff. At this advanced level, there is still no viable treatment or cure. Only when treatment is initiated at the earliest stage of the disease is it effective. These could potentially save a life in addition to lowering the cost of the illness. The majority of ways can identify Parkinson's disease after it has advanced, which results in basal ganglia, which regulates movement of the body with a small quantity of dopamine, losing about 60% of their dopamine. The presence of diminutive precursors to chronic diseases, especially neurologically based ailments such as Parkinson’s can indicate and diagnose them in their earliest stages. Parkinson’s disease (PD) is characterized by symptoms such as spasms in the limbs, jaw, and head, rigidity in the limbs and trunk, slow movement, etc. It is important to notice these preliminary symptoms early on to avoid developing Parkinson's disease. This project proposes algorithms used on the dataset to predict PD. Two kinds of datasets are used; one voice dataset and another spiral drawing dataset, and algorithms are used in these datasets to predict the disease and to show the results a user-friendly Web-Application is developed. The algorithms used are K-Nearest Neighbours (KNN) on voice dataset implementation and Random Forest on spiral drawing implementation.
The Influence of Thermoelectric Properties of Nanomaterial and Applications
Authors: Kasarla Sarveshwar , Saravanan Vimala , Prasanth Vidhya , Selvam Manjula
Published: February 2023

To assess the thermoelectric qualities of low-dimensional materials, a nanomaterial was created. Due to its inherent nanoscale structure, a one-dimensional thermoelectric material is predicted to have superior thermoelectric characteristics and low heat conductivity. High efficiency thermoelectric energy conversion devices can be realised by taking use of these better features. Graphene and hexagonal boron nitride (h-BN), two-dimensional nanomaterials, are thermally efficient. Due to the differences in the crystal lattice and electrical structure between graphene and h-BN, a new material with novel thermal properties is created when the two join to produce a planar C-BN hybrid structure or a van der Waals heterostructure. We concentrate on these new qualities while reviewing the two new materials, as their thermal properties affect their structure, size, and number of layers. To assess the thermoelectric qualities of low-dimensional materials, a micro-instrument was created. Due to its inherent nanoscale structure, a one-dimensional thermoelectric material is predicted to have superior thermoelectric characteristics and low heat conductivity. High efficiency thermoelectric energy conversion devices can be realised by taking use of these better features. In this study, we used micromachining to create microdevices to examine the thermoelectric characteristics of low-dimensional materials. The system comprises of a tiny thermocouple with a freely suspended heating element acting as the sensing element. Manipulation was used to place an array of Bi2Te3 nanowires made using the silicon template approach on the microdevice. To show the device’s ability to assess the thermoelectric properties of nanomaterials, measurements of the Bi2Te3 bundle’s electrical, thermal, and Beck coefficients were made. More information about this source text source text necessary for further translation details. We offer a synthetic method for producing Cu2ZnGeSe4 nanocrystals with a limited size range and a predetermined composition. By hot pressing, these nanocrystals were employed to create nanomaterials that were tightly packed. These nanoparticles’ Cu2ZnGeSe4 thermoelectric characteristics have been demonstrated to be very good. A figure of merit of up to 0.55 at 450 °C has already been achieved through early refinement of the nanocrystal composition. The performance of thermoelectric (TE) materials is currently the subject of intense research. One of the suggestions for enhancing their TE performance is nanostructuring. However, a nanomaterial’s shape can have a big impact on how it behaves under tension. In this study, we showed that this action uses a microwave-assisted chemical pathway to create zinc oxide (ZnO) in two distinct forms. The molar ratios of the initial precursors were altered to create nanoparticles (NPs) and nanorods (NRs). According to the results, NRs have better TE properties than NPs, especially at higher temperatures.
Produção do conhecimento sobre atividades físicas e compreensões de corpo durante a pandemia da COVID-19
Authors: Aquino Lívia Silveira Duarte , Santiago Joselita da Silva , Pereira Larissa Maria de Paiva Ribeiro , Medeiros Rosie Marie Nascimento de , Silva Priscilla Pinto Costa da , Mendes Maria Isabel Brandão de Souza
Published: February 2023

O objetivo da pesquisa é analisar como a produção do conhecimento sobre as atividades físicas no confinamento durante a pandemia da COVID-19, aborda a relação entre o corpo biológico e o corpo cultural. Para isso, foi realizada uma revisão sistemática na BVS Saúde, sendo identificadas 7 produções. Constatou-se que a maioria dos trabalhos aborda o corpo apenas em seu aspecto biológico, em detrimento do corpo biopsicossocial, e verificou-se ainda que os estudos que transcenderam essa abordagem buscaram destacar os benefícios da atividade física para saúde mental considerando o fato do ser humano ser biocultural, portanto, fortemente marcado também pelas relações sociais e culturais que o cercam. Mesmo com este avanço, ainda há estudos que desconsideram os aspectos sócio culturais do corpo humano, deixando uma preocupação pela constatação de que talvez a Educação Física, enquanto área do conhecimento, ainda não esteja ampliando seu olhar para o ser em movimento com a necessária abrangência que o tema exige. Assim, sugere-se para futuras pesquisas, sobre a temática, a construção de um diálogo entre os conhecimentos advindos das ciências naturais e humanas para alcançar esse objetivo.Por fim, registra-se algumas limitações encontradas, dentre elas a necessidade de consultar outras bases de dados e para outros contextos, além do brasileiro, a fim de ampliar o rastreio de informações e assim verificar se as percepções observadas durante a realização desta revisão se repetem nas demais plataformas.
Physical Activity Level and Influence on Mood States, Anxiety and Self Image in University Students
Authors: Stoduto Alejandro de Moraes , D'alpino Isabela Ambrósio , Lima Deivide Telles de , Testa Junior Ademir , Zanini Gabriel de Souza
Published: February 2023

The regular practice of physical activities in the life of university students becomes secondary, either due to high academic demands or abrupt changes in lifestyle. However, as this academic environment is competitive and demanding, it can in turn change mood levels, anxiety and perception of these students; in this sense the exercise can be a great ally in facing the adversities of the academic period. Thus, the present study sought to evaluate and compare the levels of mood, anxiety and perception of body self-image of 66 university students. The results showed that the level of physical activity influenced the Total Mood Disorder (TMD), with the most active groups having an improvement over time [(SA group (6.55±29.03%, p=0.046) and MA (9.48±28.94%, p=0.023)]. However, the anxiety and self-image of the students was not verified improvement. Thus, it can be understood that higher levels of habitual physical activity can help university students in their mood patterns, thus helping with an improvement in the academic environment.
INTERNAL AND EXTERNAL FACTORS OF ACCOUNTING STUDENTS IN THE IMPLEMENTATION OF ONLINE LEARNING DURING THE COVID-19 PANDEMIC ERA IN PEKALONGAN
Authors: Mutmainah Ina , Ali Fachri
Published: February 2023

The present study showcases the effect of accounting understanding level, lecturer competence, and student achievement on online learning in the Covid-19 pandemic through learning motivation. The population of this study was accounting students situated at universities in Indonesia. 153 students of a university in Pekalongan, Central Java volunteered to participate. Purposive sampling was employed, and data were garnered through questionnaires. The distributed data were processed using a Likert scale. Path analysis was carried out to analyze data. Study findings expose that the level of accounting understanding, lecturer competence, and student achievement had no effect on online learning. The level of accounting understanding and student achievement did not have a significant effect, while lecturer competence had a significant effect on online learning through learning motivation. This empirical evidence provides an overview of learning evaluation materials for higher education in Indonesia related to students’ abilities in online learning during the Covid-19 pandemic so that in the future it will be more effective and ready to compete in the digital era 4.0.
PENGARUH PERSEPSI MAHASISWA TENTANG INVESTASI TERHADAP MINAT BERINVESTASI SAHAM DI PASAR MODAL
Authors: Prihatin Khristina Sri
Published: February 2023

This study aims to determine how students' perceptions of stock investment are, to find out how much students were interested in investing in stocks in the capital market, and to analyze how the perceptions of students majoring in Accounting Education at the University of Banten Jaya about investment affect interest in investing in stocks in the capital market. This study uses a quantitative research method consisting of two variables, namely student perceptions (X) and interest in investing (Y). The object of this research is students of Accounting Education, Faculty of Teacher Trainin g and Education, University of Banten Jaya. The source of the data used is primary data in the form of questionnaire results then tabulated and processed using SPSS 25.0 software with a series of tests and provisions that have been scientifically tested and secondary data includes documents and archives. Based on the results of the study, it was found that 40 respondents (53.3%) had a positive perception of stock investment, and 42 respondents (56%) had a high level of interest in investing in stocks in the capital market. The Influence of Student Perceptions About Investments on Interest in Investing in Stocks in the Capital Market (4.254>1.996) tcount> ttable, as much as 19.9% interest in investing in stocks is influenced by student perceptions of investment, the remaining 80.1% is influenced by other variables that are not included in this research.
PENGARUH PERSEPSI MAHASISWA FKIP TERHADAP MINAT MENJADI GURU
Authors: Gunawan Iba , Andayani Andayani
Published: February 2023

This study aims to find out how students perceive interest in becoming a teacher and to find out whether there was an influence from student perceptions on interest in becoming a teacher for students in the faculty of teacher training and education at the University of Banten Jaya 2017-2020. The population in the study were 275 students. Determination of the sample using the formula according to Suharsimi Arikunto (2013) by taking 40% of the population as many as 110 students who became the sample. This research was processed using a simple regression technique. The results of this study indicate that the t-test between students’ perceptions of interest in becoming a teacher has a significant influence.
PENGARUH STRUKTUR MODAL, UKURAN PERUSAHAAN, LEVERAGE, DAN INVESMNET OPPORTUNITY SET (IOS) TERHADAP KUALITAS LABA
Authors: Erawati Teguh , Rahmawati Dewi
Published: February 2023

Earnings quality is earnings that reflect the continuation of earnings in the future, which is determined by the accrual component and cash conditions that show the actual financial performance of the company. This study aims to prove the effect of capital structure, firm size, leverage and investment opportunity set (IOS) on earnings quality. The research method used is purposive sampling with a total sample of 58 companies listed on the Indonesia Stock Exchange (IDX). This research was conducted using secondary data with the year of observation, namely 2017-2020. The data is obtained from financial statements taken from www.idx.com. The data analysis method used is descriptive statistical test, classical assumption test and hypothesis testing. The results showed that capital structure, leverage and investment opportunity set (IOS) did not have a significant effect on earnings quality, while firm size had a significant effect on earnings quality.
PENGEMBANGAN MEDIA PENCATATAN TRANSAKSI KEUANGAN UNTUK PEMBUATAN LAPORAN LABA RUGI PADA USAHA KECIL
Authors: Astutik Ayu , Mulyati Budi
Published: February 2023

This study aimed to (1) develop a record media for financial transactions for small businesses. (2) knowing the assessment from material experts, design experts and business practitioner experts on the financial recording media of the income statement in small businesses, (3) knowing the assessment from the grocery store owner on the financial recording media of the income statement. The method used in research was R&D. The research stage used was development research developed by Sugiyono with specifically modification stages, i.e. potential and problems, data collection, product design, design validation, design revision and product trial. This research was conducted at a small grocery store in Ranjeng Village, Ciruas District. The research result: The assesment from material expert showed the number of 3.37 (very good), the research results from the design expert showed the number of 4, (very good), and from the business practitioner showed number of 4 (excellent). The assessment response from small shop business owners showed an assessment that was in the range of 3.07 (good)-4 (very good). So it can be said that in general, the media developed was already good.