bluuebunny/crossref_metadata_2025 huggingface dataset:
Structure and kinematic history of the Acatlán Complex in the Nuevos Horizontes - San Bernardo region, Puebla
Authors: Weber Bodo , Meschede Martín , Ratschbachef Lothar , Frisch Wolfgang
Published: April 2023

Las rocas metamórficas e ígneas del Paleozoico, que forman el basamento de la parte norte del terreno Mixteca en el sur de México, se han agrupado como el Complejo Acatlán. Seis fases de deformaciones distintas se han diferenciado por di' tintas facies metamórficas, grados de ductilidad y correlación temporal. La primera deformación (D) está caracterizada por metamorfismo de alta temperatura (M1), que se sobreimpuso a eclogitas y culminó en anatexis y la intrusión de granitos. Durante esta deformación crecieron grandes micas claras y megablastos de feldespato potásico en las rocas metasedimentarias. La segunda deformación (D2) causó retrometamorfismo (diaftóresis) llegando hasta un metamorfismo de bajo grado (esquisto ·Verde). Las micas de la M1 están conservadas como porfidoclastos dentro de la foliación S1• Durante esta defor- mación se han fracturado con una temperatura menor, mientras que en la foliación S2 están sustituidas por sericita. La defor- mación (D2) causó recristalización dinámica de cuarzo. La tercera deformación (D3) plegó el área en estructuras isoclinales y estrechas con vergencia hacia el poniente. Los sedimentos, depositados entre D2 y D3, sufrieron un metamorfismo de muy bajo grado, y tienen al igual que los granitos, intrusados durante la D3 a un nivel de la corteza superior, una foliación S3. La cuarta deformación (D4) está caracterizada por pliegues tipo “kink”, una zona empinada de cizalla cataclástica y planos de estrías. Los cálculos de tensores de paleoesfuerzo dan ejes subhorizontales con una dirección de NE-SW. La mayor parte de las poblaciones de fallas frágiles está relacionada con la quinta deformación (D5), con ejes y también subhorizontales, con una dirección de ENE-WSW. Fallas normales definen la sexta deformación (D6) con ejes subverticales y ejes subhorizontales con direcciones alrededor de N-S.doi: Sin doi
Geophysical and hydrogeological characterization of the sub-basins of Apan and Tochac (Mexico basin)
Authors: Huízar-Álvarez Rafael , Campos-Enríquez J. O. , Lermo-Samaniego J. , Delgado-Rodríguez O. , Huidobro-González A.
Published: April 2023

A partir de los datos de resistividad, gravimétricos, magnéticos, hidrogeológicos y geoquímicos, se describen las principales características del sistema hidrogeológico de las subcuencas de Apan y Tochac, pertenecientes a la cuenca de Mexico. Ambas subcuencas presentan un relleno volcano-sedimentario de aproximadamente 600 m de espesor, y están separadas por la cordillera de Apan, la cual se extiende a lo largo de una gran falla de orientación NE-SW, definida como una prolongación del lineamiento regional que une a los volcanes de Tlaloc y Telapon. La subcuenca de Apan tiene un bajo nivel de actividad sísmica. La correlación de la información geofísica con los datos de pozos confirma la existencia de un sistema hidrogeológico que incluye acuíferos intergranulares, mixtos y fisurados con transmisibilidad entre 5.7 X l0-3 m2fs y 1.1 x 10-1 m2/s, y permeabilidad aproximada de 4.0 x 10-4. El acuífero fisurado constituye el área de recarga, mientras los otros dos conforman un acuífero semi-confinado cuya única descarga proviene del bombeo de los pozos. La zona no~saturada tiene 60 m de espesor y la superficie potenciométrica fluctúa 0.30 m anualmente. Sin embargo, en algunas zonas del área en estudio no se observaron estas fluctuaciones. De acuerdo con la información litológica de los pozos y la interpretación de los Sondeos Eléctricos Verticales, el mayor espesor del acuífero se encuentra en la porción sur de la subcuenca de Tochac. Los valores de resistencia eléctrica y los estudios hidrogeoquímicos indican la presencia en profundidad de agua de buena calidad ligeramente mineralizada.doi: sin doi
Blockchain Based Transaction Management System
Authors: Joglekar Prof. Dr. Pushkar , Parvekar Vedant , Sabde Aditya , Rasal Omkar , Rasal Yogesh
Published: April 2023

Abstract: The technology that supports bitcoin, known as blockchain, is still in its development. Blockchain technology has the potential to improve existing corporate procedures to make them more collaborative, transparent, secure, and effective.. The banking sector is among the first to take advantage of this technology's disruptive potential. One of the most intricate bank payment systems in the entire globe is the Indian banking system. The current infrastructure that the Indian banking system uses is centralized and based on the real-time gross settlement system. This centralized architecture causes transactions to process slowly and result in wasting. Additionally, it costs a lot for security and recovery considerations. Systems for real-time gross contracts should indeed meet high expectations for speed, stability, and security. The primary objective is to develop a system that provides security, confidentiality, and a decentralized money lending mechanism rather than converting old system to the blockchain platform. Here, a novel strategy that encourages a decentralized system and services built on the Ethereum blockchain is progressed. The system enables a number of services using distributed ledger technology, including loan checking, money transfer, and money deposit, among others.
Formulation and Evaluation of Multiple Emulation of Diclofenac Sodium
Authors: Kumar Mukesh , Sahu Nitin , Israr Mohammad , Rain Md Wasim , Shsah Mohd Ashraf , Rathi Dr. Jagdish , Singh Dr. Anjita , Sharma Rahul
Published: April 2023

Abstract: Multiple emulsion is novel approach of drug delivery system for enhancement of bioavailability and pharmacological activity. It is important to prevent the problem of oral drugdelivery system and they are stabilized by using of combination of hydrophilic and lipophilic surfactant. The specific ratio of surfactant concentration is responsible for maintaining the stability of multiple emulsions, the importance of this study was to prepare multiple emulsion of Diclofenac sodium by using two step emulsification process, by using the non-ionic surfactant units. In multiple emulsion, the stability of multiple emulsion was evaluated, percent entrapment efficiency as well as in vitro studies are conducted. The objective of this study was to prepare multiple emulsion of Valsartan by two step emulsification using different nonionic surfactants, Tweens & Spans, and evaluate for stability,percentage drug entrapment, in vitro drug release.
Fastag Fraud Detection: A Literature Survey
Authors: Bhavar Vipul , Borkar Vishakha , Hirave Tanvi , Vishwanathan Harsh , Asati Ranjita
Published: April 2023

Abstract: National Payments Corporation of India (NPCI) has developed the National Electronic Toll Collection (NETC) program to meet the electronic tolling requirements of the Indian market.The use of FASTag is prevalent in modern society. However, it is clear that the number of FASTag frauds in the global integration and existing protection system is constantly increasing. This is why the issue of FASTag fraud detection is very important. Various FASTag frauds occur and there is no means to detect or prevent them. Among the many frauds, we will try to reduce the fraud where drivers of heavy vehicles issue and use FASTags that are intended for light vehicles. In this way, drivers of heavy vehicles are exempted from paying the higher tolls that are set for heavy vehicles. FASTag fraud detection is used to solve this problem. The system will be able to identify the type of vehicle and the FASTag amount paid. Using this system, FASTag fraud detects if any anomaly has occurred and alerts the system accordingly
Developing An E-Commerce Web Application with ReactJS and Firebase
Authors: Yerlekar Ashwini , Rajpurohit Vipul , Kunte Shreyas , Shende Nakul , Kamble Tushar , Ingole Shreyash , Admane Shubham
Published: April 2023

bstract: With the rise of e-commerce platforms, shopping is now possible anytime, anywhere. Web application development is a great solution for the shopping needs of people who want to avoid the hassle of physical stores. The web application will provide users with a user-friendly interface that will allow them to easily purchase a wide range of products. This app will include various features like product search, filtering, sorting, shopping cart management, payment gateway integration. In contemporary times, most people use technology to live their lives and meet their daily needs. In this generation, most of us use e-commerce sites to buy clothes, groceries, and electronics. Additionally, this app will provide users with personalized recommendations based on their purchase history, search history, and preferences. The application is designed to provide users with stable and fast engagement. All in all, it will provide a convenient and a safe platform for users to purchase products online. With its powerful features and modern technology, the app will help users save time and effort while providing a hassle-free shopping experience.Loading time and minimalist design. The ambition of this article is to discuss the development of an app that provides users with a seamless shopping experience while ensuring security and comfort.
Analysis of Stock Price Prediction Using ML Techniques
Authors: S Sabarinath , R Thirumalaivasan , S Shiam , S Mohamed Aashik M , Sudhakar K. , Rama Dr. P.
Published: April 2023

Abstract: Time series forecasting has been widely used to determine the future prices of stock, and the analysis and modelling of finance time series importantly guide investors’ decisions and trades. This work proposes an intelligent time series prediction system that uses sliding-window optimization for the purpose of predicting the stock prices using data science techniques. The system has a graphical user interface and functions as a stand-alone application. The proposed model is a promising predictive technique for highly non-linear time series, whose patterns are difficult to capture by traditional model.
Water Utility Conservation and Management Approach Using IoT
Authors: S Swathi , C Suganya. , N Hariharan. , I Bildass Santhosam.
Published: April 2023

Abstract: The demand for water supply has increased unpredictably worldwide over the past few decades, posing a major challenge. To overcome this challenge, an IoT-based water monitoring and control approach is presented, which supports realtime internet-based data collection. The device comprises a computer system (central hub), an IoT module, a switching unit, and a Zigbee module. The Internet of Things is a network of devices embedded with electronics, software, and sensors that enable them to exchange and analyze data. The centralized hub distributes water individually based on the needs of each household, assisted by IoT integration of communications, control, and information processing across the systems used. This allows water quantity and quality to be sensed at each structure in a particular sector, providing remote access control of the water supply. The centralized hub monitors and shares water among localized tanks or resupplies water from its reservoir according to a rank’s deficit or excess water level. Personal area networks are created in this scenario where a wireless connection is required across the system. UV treatment is deployed to improve the quality of water distributed to every household, and fluoride content level along with hardness checking is done using respective test meters. Overall, the IoT-based water monitoring and control approach design presents an innovative solution to the increasing demand for water supply, enabling efficient distribution and ensuring water quality.
Micro-Analysis of Rainfall Using Statistical Techniques
Authors: Patil Asawari , Shinde Prasad , Jadhav Mohan
Published: April 2023

Abstract: Rainfall over a region across the earth is the prima face reason of its uniqueness. Data is taken from official website of Indian Meteorological Department. Figure 2 shows that the district wise comparison of average rainfall in Maharashtra. Figure 3 shows that the district wise comparison of average rainy days in Maharashtra. There is significant difference between actual and normal (expected) rainfall of the all districts over the period 1998-2017. There is significant difference between average actual and normal (expected) rainfall of the districts in Maharashtra.
Breast Cancer Prediction Using Machine Learning
Authors: Gujar Riddhi R. , Rajurkar Apurwa A. , Naik Yash G. , Bhise Shreya D. , Shaikh Dr. Alam N.
Published: April 2023

Abstract: Worldwide, breast cancer is the most common cause of death for women, and increasing survival rates require early identification. Medical scans like mammograms and ultrasounds can be used to predict breast cancer using convolutional neural networks (CNNs). The architecture of CNNs, training data and methods, and performance evaluation criteria are all reviewed in this work as well as the current state of research on CNNs for breast cancer prediction. Also, the benefits and drawbacks of CNNs against conventional techniques for the identification of breast cancer are explored. Although though CNNs have the potential to lower false-positive outcomes and have higher accuracy rates, further testing and study are required to assure their dependability. Also, it’s critical to consider moral concerns like data privacy and bias in machine learning algorithms. Thus, using CNNs to predict breast cancer has enormous potential to increase early detection and, eventually, save lives.So, our objective is to develop a model that can predict breast cancer from mammography images, which will help patients choose between various tests as well as assist medical students in validating their study.
Drugged Eye Detection Using Image Processing
Authors: Premalatha Mrs. M. , Kumar A. Heymath , Kumar M. Manoj , Pavithran P. , Shatyadeep K.
Published: April 2023

Abstract: Drugs are a major problem in economic and many losses in worldwide. In this project, an image processing approach is proposed for identifying drugged eye based on convolutional neural network. According to the CNN algorithm, eye image details are taken by the existing packages from the front end used in this project. However, it can take a few moments. So, this proposed system can be used to identify drugged eyes quickly and automatically. The eye images dataset are taken from Kaggle. These images are taken as a training set for this drugged eye detection. This proposed approach is composed of the following main steps that getting input image, Image Preprocessing, identifying reddish places, highlight those affected places, Verifying training set, showing result. Few types of eyes like drugged socially may missed to identify. This approach was tested according to drugged eye type and its' stages, such as drug consumed and not consumed. The algorithm was used for detecting the white area of eye present in given input image. Images were provided for training, such as drugged eye images and normal eye images. Before the image processing, images were converted to color models, because of find out the most suitable color model for this approach. Local Binary Pattern was used for feature extraction and Support erosion method was used for creating the model. According to this approach, drugged eyes can be identified in the average accuracy of 95%.
Study on Groove Shape in Park Lock System
Authors: Roy Abhirup , Kirti Yash
Published: April 2023

Abstract: In order to reduce the stress concentration in Pawl grooves with different shapes or tips with variable radii geometry are studied and are compared to the samples without any grooves, the shape that offers the best stress reduction is studied and optimised further.
A Review of Machine Learning and AI-Based Approaches to Detecting Cyberbullying on Social Media
Authors: D Harish , M Manimaran , P Jayashakthi Vishnu
Published: April 2023

Abstract: With rapid rise in the use of social media, cyber-bullying has become a significant concern, affecting individuals of all ages and backgrounds. Finding cyberbullying on social media is essential to building a secure and welcoming online community. The various approaches and techniques used to identify cyberbullying on social media are examined in this research, ranging from traditional keyword-based strategies to more sophisticated machine learning and NLP-based algorithms. We also draw attention to the difficulties and restrictions posed by the use of current techniques, such as their poor accuracy, lack of standardization, and privacy issues. We also go over the significance of addressing social and cultural disparities as well as the necessity of ethical concerns when identifying cyberbullying. Our review provides a comprehensive understanding of the current state of cyberbullying detection on social media, along with recommendations for future research. Ultimately, combating cyberbullying and fostering a more supportive and positive online environment depend on the development of more precise and reliable detection techniques
Leaf Disease Detection System
Authors: Gupta Sahil , Pandey Vivek , Pandey Pravesh , Verma Mukul , Shaikh Hasib
Published: April 2023

Abstract: Agricultural productivity is something on which economy highly depends. This is the one of the reasons that disease detection in plants plays an important role in agriculture field, as having disease in plants are quite natural. If proper care is not taken in this area then it causes serious effects on plants and due to which respective product quality, quantity or productivity is affected. For instance a disease named little leaf disease is a hazardous disease found in pine trees in United States. Detection of plant disease through some automatic technique is beneficial as it reduces a large work of monitoring in big farms of crops, and at very early stage itself it detects the symptoms of diseases i.e. when they appear on plant leaves. This paper introduces an efficient approach to identify healthy and diseased or an infected leaf using image processing and machine learning techniques. Various diseases damage the chlorophyll of leaves and affect with brown or black marks on the leaf area. These can be detected using image prepossessing, image segmentation. Support Vector Machine (SVM) is one of the machine learning algorithms is used for classification. The Convolutional Neural Network (CNN) resulted in a improved accuracy of recognition compared to the SVM approach.
Conflicts in Relationships with Respect to English Literature and Female Perspective
Authors: Kamal Ms. Deepali
Published: April 2023

Abstract: Though the principle of gender equality is enshrined in the constitution of India, though the women are provided equal rights that of men, though the women are allowed to get education, though the women are considered one of the most important asset for the nation but still the questions that remain unanswered are how far does it matches the reality? How far women and their interests are kept in mind? Are their emotions even considered emotions or just considered and ignored as mood swings. In this paper we will study about conflicts in relationships in respect with english literature and female perspective. We will study about how feminism is included or excluded in the works of literature. Feminism is about women getting equal rights and opportunities as men without spoiling or dominating the rights of men. But though there are so many measures taken to promote feminism in a positive way still we come across novels, poems, dramas and so that somehow creates false image of women and portrays women as an inferior character therefore we will study in detail the role of women in famous works of english literature mainly in the play Hayavadana by Girish Karnad and the play Twelfth Night by William Shakespeare. Hayavadana is a typical Indian play that hold various themes wherein we will be focusing on women as an object and Twelfth Night on the other hand is a western play, also having various themes but the key theme will be patriarchal dominance over female emotions leading to relationship conflicts. We are aiming to study that how sometimes literature set gender roles and promotes gender inequality and women inferiority. Ultimately this portrayal leads to certain other issues that women find offensive. It leads to self doubts and under confidence in women. As women are shown sensitive and powerless in the books of literature the society starts to accept her as inferior and dependent and this leads to conflicts and problems between women and society, women and family, the downfall and abuse in the relationship and so on
SE-VFC: A Secure Framework for Computation Outsourcing in Vehicular Fog Computing Environments
Authors: Vaishnavi Bhavya , V Dr. Praveen Kumar K
Published: April 2023

Abstract: SE-VFC is a proposed computing scheme that addresses the challenge of providing secure and efficient outsourcing computing in vehicular fog computing. Vehicular fog computing is a paradigm that involves the utilization of computing resources in vehicles to provide various computing services to end- users. However, since fog vehicles may be untrusted, there is a potential for malicious operations that can cause serious accidents. To address this challenge, SE-VFC proposes the use of a secure and efficient outsourcing computing scheme that involves fog vehicles with computing resources. The scheme utilizes lightweight Boneh-Lynn-Shacham (BLS) signature and group signature for batch anonymous authentication of fog vehicles while preserving their privacy in multiple outsourcing tasks. This means that fog vehicles are authenticated and verified without revealing their identities, which helps to protect their privacy. Additionally, SE-VFC ensures the correctness of the computing results by verifying them. This helps to ensure that the results produced are accurate and reliable. Compared to existing schemes, SE-VFC has relatively low communication and computation overhead, making it efficient for batch authentication in multiple computing tasks. The effectiveness and practicality of the proposed scheme have been verified through extensive simulation results. Overall, SE-VFC is an important contribution to the field of vehicular fog computing, as it addresses the challenge of providing secure and efficient outsourcing computing while also ensuring the privacy and correctness of the computing results.
Generation of RBC, WBC Subtype, and Platelet Count Report Using YOLO
Authors: Abhyankar Vaishnavi , Kene Rashmi
Published: April 2023

Abstract: Artificial intelligence introduced a way to combine machines’ computing ability with human intelligence. Machine learning is a sub-branch of AI that consists of different algorithms to implement concepts of AI in practical terms. But when a machine has to process numerous amounts of data, deep learning algorithms come into the picture. It is observed that when a computing system has to deal with image data then neural network algorithms give efficient ways to process them and draw unique patterns from them. Object detection is the task of identifying required objects from an image. This type of technology plays a crucial role in medical image processing. Some algorithms can efficiently identify and classify objects from an image. It is observed that Fast R-CNN and Faster R-CNN, mask R-CNN, have given pretty good accuracy while performing such tasks. But when time is a concern for a system, such methods put an obstacle of training time and architectural complexity. The You Only Look Once (YOLO) object detection method has introduced a new way of processing images in a single pass. This algorithm is famous because of its speed and correctness. There are numerous models of YOLO developed now which include YOLOv1 to YOLOV8. This paper gives the performance of the latest version of YOLO on the blood cell dataset.
Religião, arte e cultura: multiplicidades convergentes
Authors: Reinaldo F. Martins Filho José , Carvalho da Silva Daniel
Published: April 2023

É no seio da cultura que a religião se apresenta. A relação entre o ser humano e a cultura é de interdependência. Ambas se constituem e se mantêm mutuamente enquanto tal. Isto porque a imagem de uma natureza humana constante, independente de tempo, lugar e circunstância, de estudos e profissões, modas passageiras e opiniões temporárias, pode ser uma ilusão. O que o homem é pode estar tão envolvido com onde ele está, com quem ele é e no que ele acredita, que é inseparável dele. A antropologia tem a firme convicção de que não existem, de fato, homens não modificados pelos costumes de lugares particulares; nunca existiram e nem poderiam existir. Portanto, não existe uma natureza humana. Os seres humanos são pura e simplesmente o que a sua cultura fez deles. Não dirigido por padrões culturais, o comportamento do ser humano seria virtualmente ingovernável, um simples caos de atos sem sentido e de explosões emocionais, e sua experiência não teria praticamente qualquer forma. A cultura é a totalidade acumulada dos padrões culturais. Ela não é um ornamento da existência humana, mas uma condição essencial para ela, a principal base de sua especificidade (GEERTZ, 1998). Considerando a diversidade de expressões religiosas que compõem a cultura brasileira, as Ciências da Religião muito têm se esforçado para estabelecer a natureza do substrato religioso que subjaz a todas as manifestações e compreensões da arquitetura do sagrado no interior das diferentes formas de nossa multiforme realidade cultural.
res judicata of Countervailing Defense
Authors:   Wonkwang University Legal Research Institute has, Phee Jung-Hyun , Bae Jun-Ho
Published: April 2023

Article 216 of the Civil Procedure Act stipulates that in paragragh 1, a final judgement has res judicata only if it is included in the order. Even if the judgement is confirmed, if the judgement in the grounds of judgement is not binding, the dispute may be reproduced and the judgements in the grounds of judgement may be contradictory, so it is a question of whether to recognize the res judicata in the grounds of judgement. On the other hand, as an exception, the determinatioin of whether or not a claim claiming offset in paragragh 2 is established is determined to have res judicata only for the amount opposed to offset. The purpose of acknowledging the res judicata in the court’s judgement on the offset claim is that if the res judicata is not recognized, the dispute over the existence of the plaintiff’s claim will be transformed into a dispute over the existence of the counterclaim filed in another lawsuit, preventing the counterclaim from double exercising the counterclaim. Therefore, in order to understand the legal principles according to the purpose in detail, this paper examined the res judicata power of the countervailing defense. First, the requirements for recognizing res judicata will be divided into automatic bonds and passive bonds. In the former, we will examine whether the court's practical judgement on automatic bonds is necessary, whether the precedent (suspension condition theory) that the judicial effect of the countervailing defense is appropriate, and whether the expression of intention to set off, which is the originally effective time, reaches the other party (revocation condition theory). In the latter case, the existence of passive bonds and whether the passive claims are claims judged as litigation items (or equivalent thereto) are problematic. And, in the case where the defendant makes a defense of set-off, we will review whether it is lawful for the plaintiff to submit a set-off (namely, litigation set-off and non-litigation set-off) as a re-defense. This will be considered in consideration of not only the substantive legal aspect that passive claims must exist, but also the litigation policy aspect of maintaining the stability of the litigation process and eliminating complexity. In addition, we examine the objective scope of the substrate power recognized in countervailing defense, especially if the automatic bond exceeds the passive bond amount, and if the court recognizes only a part of the claim (manual) bond amount, some of the multiple automatic bonds are recognized and some are not recognized. Furthermore, we will look at the positive and negative theories on whether res judicata are recognized in countervailing disputes other than litigation.
About the practical effect of the Law
Authors:   Wonkwang University Legal Research Institute has, Park Sung Ho
Published: April 2023

As is well known, the rule of law is the principle that power should be exercised based on laws enacted and revised by the legislature. Therefore, the rule of law is a principle that power cannot be arbitrarily exercised or exercised by a person in power, but must be exercised only on the basis of law. In other words, the rule of law is to prevent abuse of power by limiting the arbitrary and subjective exercise of power by requiring the exercise of power to be based on the law. However, opinions are still divided as to why the rule of law is necessary and what it means. The rule of law is a principle to prevent and limit abuse of power by requiring the exercise of power to be based on the law, or guarantee and protect individuals' freedom and rights by limiting the exercise of power to be based on the law. These various views on the rule of law are related to what the national community wants to achieve through the rule of law. I think that the exercise of power is to prevent abuse of power and to guarantee and protect individuals' freedom and rights by demanding that it be based on the law. In other words, when the exercise of power is arbitrary and subjective by the person in power, it only brings about the expansion of power, but individual freedom and rights are bound to be limited. Therefore, the rule of law should be exercised on the basis of 'law' rather than the subjective will of individuals or power, and infringement of individual freedom and rights by powerful people or power groups should not be recognized without the basis of law. However, given that the law is enacted by the power group and reflects the subjective will of the power group, it is problematic to call it the rule of law if the exercise of power is based on the law. This is because if power is exercised based on the law only by the arbitrary and subjective will of the powerful person or the power group, it can be reduced to a tool that can suppress individual freedom and rights. In other words, if power is exercised based on laws only for power people or power purposes, it can mean the expansion of power, not the restriction and abuse of power. Therefore, if the purpose of the rule of law is to guarantee and protect individuals' freedom and rights, the law for the rule of law should be recognized only when power is exercised based on the law that is recognized as having practical effect to guarantee and protect individuals' freedom and rights.
Efecto de dos porcentajes de drenaje sobre pepino (Cucumis sativus) cultivado en invernadero
Authors: Monge-Pérez José Eladio , Loáiciga-Arias Julio César , Salazar-Salazar Werner , Loría-Coto Michelle
Published: April 2023

Introducción: La tasa de drenaje es un factor importante en la producción hidropónica. Objetivo: evaluar el efecto de dos tasas de drenaje sobre el rendimiento y la calidad de pepino (cv. Modan) de invernadero en las épocas seca y lluviosa. Métodos: Utilizamos “fertirrigación” y fibra de coco como sustrato. Resultados: En todas las categorías de calidad, no hubo diferencias entre dosis de riego para el número de frutos por m2, peso de frutos y rendimiento; mientras que el porcentaje de sólidos solubles totales fue mayor al 10% de riego. Los pepinos de época lluviosa tuvieron más frutos totales por m2; mayor peso de frutos comerciales; y mejor rendimiento total, de segunda y tercera calidad. Conclusión: En estas condiciones, una tasa de riego del 10% ahorrará agua y nutrientes, y aumentará la rentabilidad del cultivo.
Conflictos entre humanos y fauna silvestre en una zona de amortiguamiento de San Ramón, Costa Rica
Authors: Solano-Gómez Rebeca , Mora José Manuel
Published: April 2023

Introducción: Actualmente, la biodiversidad está administrada principalmente por áreas protegidas, pero la proximidad con las actividades humanas genera conflictos, los cuales están poco estudiados en los trópicos. Objetivo: Estimar el conflicto entre humanos y vida silvestre en la zona de amortiguamiento de la Reserva Biológica Alberto Manuel Brenes, San Ramón, Costa Rica. Métodos: Entrevistamos a los propietarios o administradores de 59 fincas. Resultados: Registramos 540 incidentes, en su mayoría con mamíferos (N=479); los coyotes (Canis latrans) mataron 1 074 animales en 183 ataques en 12 granjas. También registramos conflictos con jaguar, Panthera onca, puma, Puma concolor, ocelote, Leopardus pardalis y tigrillo, Leopardus wiedii, que depredaron 261 animales domésticos. También se reportaron otros mamíferos y serpientes, especialmente la terciopelo, Bothrops asper. En seis ocasiones, los hechos se produjeron a más de 500m de una vivienda; sin embargo, la mayoría estaban a 0-25m de una casa (media 398m). Los campesinos han sacrificado pumas, coyotes, mapaches y serpientes y no hubo un control coordinado de instituciones, ONG y comunidades. Conclusión: Los coyotes son los animales salvajes más comúnmente involucrados y se necesita un esfuerzo coordinado que incluya tanto a las organizaciones como a las comunidades.
CDK1 as a Novel Potential Biomarker for Predicting the Prognosis of endometrioid ovarian carcinoma
Authors: Ying Xue , Wang Jianzhang , Liu Jingfang , Xing Jie , Zhang Jiejie , Yu Aijun , Zhang Xinmei
Published: April 2023

Objective: Endometrioid ovarian carcinoma (EOC) is gynecological
malignancy. Prognostic classification of EOC remains challenging, and
the role of molecular markers in predicting prognosis is unclear.
Cyclin-dependent kinase 1 (CDK1) has been associated with poor prognosis
in several malignancies. Here, we investigate the expression of CDK1 in
EOC and its relationship with clinicopathological features and
prognosis. Methods: We used bioinformatics, reverse
transcription-polymerase chain reaction (RT-PCR), and
immunohistochemistry to evaluate the expression of CDK1 in EOC. The
correlation between CDK1 expression and clinicopathological features was
analyzed using the chi-square test. Survival analysis was performed
using Kaplan-Meier curves and multivariate Cox analyses. Results:
CDK1 was identified as a hub gene associated with EOC using
bioinformatics analysis. CDK1 was significantly overexpressed in EOC
compared to endometriosis lesions. Positive cytoplasmic CDK1 expression
was associated with poor Disease-specific overall survival (HR=4.579,
p=0.005) and poor Progression-free survival (HR=4.333, p=0.003).
Cytoplasmic CDK1 expression was an independent predictor of
Disease-specific overall survival (p = 0.035). Cytoplasmic CDK1
expression and FIGO stage were independent predictors of
Progression-free survival (p = 0.013, p = 0.048). Conclusion:
Positive cytoplasmic CDK1 expression was associated with advanced FIGO
stage and poor prognosis, and was an independent predictor of
Disease-specific overall survival and Progression-free survival. Our
results suggest that CDK1 expression may be a useful prognostic marker
for EOC.
Quantum Computing & HPC: Compilation Stack Similarities
Authors: Alarcon Sonia Lopez , Elster Anne C.
Published: April 2023

There is a lot of focus on how Quantum Computing as an accelerator differs from other traditional HPC resources, including accelerators like GPUs and FPGAs.
In classical computing, how to design the interfaces that connect the different layers of the software stack, from the applications and its high-level programming language description through compilers, schedulers, down to the hardware, and gate-level, has been critical. Likewise, quantum computing’s interfaces enable the access to quantum technology as a viable accelerator. From the ideation of the quantum application to the manipulation of the quantum chip, each interface has its challenges. In this column feature, we discuss the structure of this set of quantum interfaces, their many similarities to the traditional HPC compilation stack, and how
these interfaces impact the potential of quantum computers as HPC accelerators.
Iridium-Catalyzed Site- and Enantioselective C(sp2)-H Borylation of Benzhydryl Ethers: Enantioselectivity Amplification by Kinetic Resolution Relay
Authors: Jing Ke , Chen Lili , Zhang Panke , Xu Senmiao
Published: April 2023

We herein report a simple ether-directed iridium-catalyzed site- and
enantioselective C(sp2)-H borylation of benzhydryl ethers for the first
time. Various chiral benzhydryl ethers were obtained with high
enantioselectivities in the presence of a tailor-made chiral bi-dentate
boryl ligand. We found that the kinetic resolution relay significantly
amplified the enantioselectivity. The synthetic utility of the current
method was demonstrated by gram-scale C-H borylation and C-B bond
transformations.
Transvaginal cerclage for prevention of preterm birth in twin pregnancies with short cervix: a prospective cohort study
Authors: Liu Ming , Xu Wenyi , Ni Xiaotian , Liu Yun , Meng Lulu , Ru Ping , Gu Zhuorong , Yan Yan , Yuan Wenjun , su xiujuan , Shi Junyao , Duan Tao
Published: April 2023

Objective: To evaluate the efficacy of transvaginal cerclage
for twins with cervical dilation or short cervix and to explore the
indicated cervical length for transvaginal cerclage. Design:
Prospective cohort study. Setting: Two tertiary hospitals in
Shanghai, China. Population: A total of 177 twins with
asymptomatic cervical dilation or cervical length ≤15 mm between 16
and 25 weeks.
Methods: The logistic regression model and generalized
estimation equation were used to compare the pregnancy outcomes between
no-cerclage group and cerclage group followed by subgroup analysis of
different cervical length. NNT and Kaplan‒Meier curves were used to
estimate the efficacy of cerclage for twins in different groups.
Main Outcome Measures: The primary outcome was gestational age
at delivery and the neonatal survival rate within 3 months after birth.
The secondary outcomes were the gestational latency from diagnosis to
delivery and the risk of preterm birth before 26, 28, 32 and 34 weeks of
gestation. Results: Compared with no-cerclage group, the
gestational age at delivery (32.09±4.50 vs. 28.29±6.20 weeks,
p<0.000) and the gestational latency from diagnosis to
delivery (10.86 [7.14,13.86] vs. 3.00 [0.50,10.29] weeks,
p<0.000) were longer in the cerclage group. The rate of
neonatal survival (86.43% [223/258] vs. 47.92% [46/96],
p<0.000) in the cerclage group was significantly higher. In
the subgroup of twins with cervical dilation or cervical length
<10 mm, twins in the cerclage group had significantly longer
gestational age at delivery (31.33±4.63 vs. 23.44±4.25 weeks,
p<0.001) and gestational latency from diagnosis to delivery
(9.07 [6.29-13.57] vs. 0.43 [0.29-1.71] weeks,
p<0.001). For twins with cervical length of 10-15mm, although
the gestational latency (12 [9.14-13.86] vs. 9.93 [6.29-12.29]
weeks, p=0.037) was significantly longer, there was no difference in
gestational age at delivery (33.05±4.16 vs. 32.40±4.33 weeks, p=0.300)
or neonatal survival rate (87.72% [100/114] vs. 80.77%
[42/52], p=0.238) between the two groups. Conclusion:
Cerclage was associated with improved maternal and neonatal outcomes in
twins with cervical dilation or cervical length <15 mm. More
evidence is needed to confirm the efficacy of transvaginal cerclage for
twins with cervical length of 10 - 15 mm.
A systematic review on experimental studies about patient adherence to treatment
Authors: Folkvord Frans , Roca-Umbert Ana , Houten Karlijn van , Liefveld Aad , Carlson Jim , Bol Nadine , Krahmer Emiel , Beets Gwenn , Ollerton Rachel Drbohlav , Turk Eva , Hrubos-Strom Harald , Nahoui Hamza , Einvik Gunnar , Schirmer Henrik , Moen Anne , Cortes Jaime Barrio , Merino Beatriz , Arroyo Pena , Fico Giuseppe , Midao Luis , Sampaio Rute , Raposo Joa Filipe , Geipel Katja , Scheckenbach Kathrin , Ruiter Laura de , Lupianez-Villanueva Francisco
Published: April 2023

Better understanding patients’ adherence to treatment is a prerequisite
to maximize the benefit of healthcare care provision for patients,
reduce treatment costs, and is a key factor in a variety of subsequent
health outcomes. We aim to understand the state of the art of scientific
evidence about which factors influence patients’ adherence to treatment.
A systematic literature review was conducted using PRISMA guidelines in
five separate electronic databases of scientific publications: PubMed,
PsycINFO (ProQuest), Cochrane library (Ovid), Google Scholar, and Web of
Science. The search focused on literature reporting the significance of
factors in adherence to treatment between 2011-2021, including only
experimental studies (e.g., randomized controlled trials [RCT],
clinical trials, etc.). We included 47 experimental studies. The results
of the systematic review (SR) are grouped according to predetermined
categories of the World Health Organization (WHO): Socioeconomic,
Treatment, Condition, Personal, and Healthcare-related factors. This
review gives an actual overview of evidence-based studies on adherence
and analysed the significance of factors defined by the WHO
classification. By showing the strength of certain factors in several
independent studies and concomitantly uncovering gaps in research, these
insights could serve as a basis for the design of future adherence
studies and models.
Optimization of superior vena cava isolation with aid of ablation index guidance
Authors: Liu Jun , Guo JInrui , Li Xiaofeng , Xia Yu , Niu Guo-Dong , Yao Yan
Published: April 2023

Objective: To investigate the optimal range of quantitative
ablation index (AI) value during superior vena cava (SVC) electrical
isolation by radiofrequency catheter ablation (RFCA). Methods:
First, in a development cohort of patients with atrial fibrillation
(AF), the RFCA with 40W was performed to complete SVC isolation guided
by the conduction breakthrough point from the right atrium to SVC. Then,
the range of AI value was calculated by offline analysis on different
segments of SVC. Lastly, for the validation of AF patients, the safety
and effectiveness of SVC isolation with the optimized target range of AI
value were evaluated with an additional adenosine test.
Results: A total of 101 patients with AF were included in the
study (44 patients in the development cohort / 57 in the validation
cohort). The segmental ablation strategy was applied in 70% of the
patients. According to the offline analysis of the AI values in the
development cohort, the target AI value range was set as 350-400. The
success rate of SVC isolation in the validation cohort was significantly
higher than that in the exploration cohort (100% vs 90.9%, P = 0.02),
and no complications occurred in the exploration cohort. During the
adenosine test, the recovery rate of electrical conduction in SVC was
significantly lower than that in the pulmonary vein (3.5% vs 17.5%).
Conclusion: The target AI value with a range from 350 to 400 is
safe and effective for high-power RFCA to complete SVC isolation.
Hydrogen isotopes in leaf and tree-ring organic matter as potential indicators of drought-induced tree mortality
Authors: Lehmann Marco , Diao Haoyu , Ouyang Shengnan , Gessler Arthur
Published: April 2023

The oxygen and hydrogen isotopic composition (δ O, δ
H) of plant tissues integrates hydrological,
physiological, and metabolic functions differently, which may allow
disentangling reasons of tree mortality. To test this, we performed a
greenhouse study and determined predisposing fertilization and lethal
drought effects on δ O and δ H
values of plant water and organic matter (OM) in leaf and woody tissues
of living and dead saplings of five European tree species. Additionally,
we measured physiological and metabolic traits. Compared to controls,
drought reduced leaf gas-exchange, predawn water potential, and stem
starch concentrations and increased δ O and δ
H values of leaf and twig water in all tested
species. These drought-induced changes generally caused an
H-enrichment in leaf and tree-ring OM, but a low and
heterogenous δ O response. δ H
values of tree-ring OM were correlated with those of leaf and twig water
across treatments and species. In contrast, the predisposing
fertilization had generally no significant effect on any isotopic,
physiological, and metabolic traits. We propose that the
H-enrichment in the dying trees is related to (i) the
plant water isotopic composition, (ii) metabolic processes shaping leaf
non-structural carbohydrates , (iii) the use of carbon reserves
for growth, and (iv) species-specific physiological adjustments. This
stress imprint on δ H but not on δ
O suggests that the further could be used as a proxy
to understand mechanisms of drought-induced tree mortality.
Acute Vision Loss due to CML Leukemic Retinopathy Reversed with Leukapheresis
Authors: Leong Sally , Do Tiffanie , Shodiya Michael , Lee Jennifer
Published: April 2023

Leukemic retinopathy is a severe complication of severe leukocytosis
that results from untreated chronic myelogenous leukemia (CML).
Immediate cytoreduction via leukapheresis may reverse ocular
manifestations and prevent permanent vision damage. We present a case of
a patient with acute unilateral vision loss found to have leukemic
retinopathy in the setting of
Timing and provenance of volcanic fluxes around the Permian-Triassic Boundary Mass Extinction in South China: U-Pb zircon geochronology, volcanic ash geochemistry and mercury isotopes
Authors: Edward Oluwaseun , Paul André N. , Bucher Hugo François Rudolf , Vérard Christian , Adatte Thierry , Sonke Jeroen E. , Schaltegger Urs , Vennemann Torsten
Published: April 2023

Anomalous mercury (Hg) contents recorded near the Permian-Triassic
boundary (PTB) are often linked to Siberian Traps Large Igneous Province
(STLIP) volcanism and the Permian-Triassic boundary mass extinction
(PTBME). However, mounting evidence indicates that the relation between
STLIP volcanism and Hg “anomalies” is not straightforward. This study
focuses on the timing and provenance of volcanic fluxes around the PTBME
in South China. We constrain carbon isotope (δC) and
Hg concentration and isotope records by utilizing high-precision U-Pb
zircon ages from two expanded deep-water marine sections spanning the
Late Permian to Early Triassic in the Nanpanjiang Basin. Results reveal
two episodes of Hg enrichment. The oldest episode predates the onset of
a large negative δC excursion, which is documented
to be older than 252.07 ± 0.130 Ma. The second episode occurred between
251.822 ± 0.060 Ma and 251.589 ± 0.062 Ma, coinciding with the nadir of
the δC excursion. Volcanic ash geochemistry and Hg
isotope compositions suggest that mercury was sourced from
subduction-related volcanic arc magmatism in the Tethys region, which
peaked between 251.668 ± 0.079 Ma and 251.589 ± 0.052 Ma. These results
are compatible with suggestions that regional arc volcanism contributed
to the causes of the PTBME in South China and provide evidence that Hg
anomalies close to the PTB are not a reliable stratigraphic marker for
the PTB extinction event. This study demonstrates that the relations
between volcanism, environmental perturbations and mass extinction
during the Permian-Triassic transition are better resolved with the aid
of high-precision U-Pb zircon ages.