bluuebunny/crossref_metadata_2025 huggingface dataset:
From Diversity Ideologies to the Expression of Stereotypes: Insights Into the Cognitive Regulation of Prejudice Within the Cultural-Ecological Context of French Laïcité
Authors: Lankester Lucie-Anna , Alexopoulos Theodore
Published: January 2021

This theoretical paper examines the context-sensitivity of the impact of cultural norms on prejudice regulation. Granting the importance of understanding intergroup dynamics in cultural-ecological contexts, we focus on the peculiarities of the French diversity approach. Indeed, the major cultural norm, the Laïcité (i.e., French secularism) is declined today in two main variants: The Historic Laïcité, a longstanding egalitarian norm coexisting with its amended form: The New Laïcité, an assimilationist norm. In fact, these co-encapsulated Laïcité variants constitute a fruitful ground to cast light on the processes underlying prejudice regulation. Indeed, it is documented that the assimilationist New Laïcité is linked to higher levels of prejudice as compared to the egalitarian Historic Laïcité. To this day, research mainly explored interindividual determinants of Laïcité endorsements and specified how these endorsements shape prejudice. Crucially, this “indirect-endorsement path” does not account for the more straightforward causal relationship between Laïcité and prejudice. Moreover, recent experimental evidence suggests that the normative salience of both Laïcité norms shape intergroup attitudes beyond personal endorsement. Therefore, in this contribution, we complement previous work by investigating the possible socio-cognitive processes driving this “direct-contextual path.” In doing so, we seek to bridge the gap of causality by investigating how the Laïcité norms can set the stage for specific regulatory strategies. Our reasoning derives from an application of the Justification-Suppression Model bolstered by classical work on mental control, modern racism and diversity ideology. From this, we sketch out the operative functioning of two distinct regulation processes: (a) one that prevents prejudicial attitudes but which can have unexpected consequences on stereotyping within the Historic Laïcité context (i.e., suppression) and (b) one that helps realize prejudice within the New Laïcité context (i.e., justification). From this analysis, we discuss the consequences for intergroup relations within and beyond the French context. In particular, we outline the importance of an adequate framing of egalitarian ideologies so that they achieve their goal to foster harmonious intergroup relations.
The Persistence of Neuromyths in the Educational Settings: A Systematic Review
Authors: Torrijos-Muelas Marta , González-Víllora Sixto , Bodoque-Osma Ana Rosa
Published: January 2021

Neuroscience influences education, and these two areas have converged in a new field denominated “Neuroeducation.” However, the growing interest in the education–brain relationship does not match the proper use of research findings. In 2007, the Organization for Economic Cooperation and Development (OECD) warned of the misunderstandings about the brain among teachers, labeling them as neuromyths. The main objective here is to observe the prevalence of the neuromyths in educators over time. After two decades of publications of research on neuromyths among in-service or prospective teachers, this work presents a systematic scientific review. To select the articles, we used the words: “teachers,” “preservice teachers,” “neuromyths” combined with the Boolean data type “and.” The search was filtered according to the following criteria: (a) identifiable author, (b) written in English, Spanish, French, Italian, or Portuguese, (c) word neuromyth in title, abstract, or keywords, (d) research with a participant's survey, (e) sample focused on educators, (f) peer-review publication index in JCR, SJR, or ESCI. The documents were found through Web of Science, Scopus, PubMed, Dialnet, ProQuest, EBSCO-host, and Google Scholar. After the search, 24 articles were identified as being of sufficiently high quality for this systematic review. This result highlights that neuromyths are still the subject of attention almost two decades after their definition. The findings present neuromyths as the consequence of a lack of scientific knowledge, a communicative gap between scientists and teachers, and the low-quality information sources consulted by teachers. In addition, the data on protectors and predictors of neuromyths is inconsistent. There is also no standard scientific methodology nor a guideline to determine a new neuromyth. The results show the need to improve the scientific content in higher education and the importance of in-service teacher training. This research justifies the requirement for university professors to be active researchers and to establish a close link with educators from other fields and levels. Neuroeducation will be the bridge that unites scientific knowledge and practical application in education, with a rigorous, standard method for the entire scientific-educational community.
Double Jeopardy-Analyzing the Combined Effect of Age and Gender Stereotype Threat on Older Workers
Authors: Manzi Claudia , Sorgente Angela , Reverberi Eleonora , Tagliabue Semira , Gorli Mara
Published: January 2021

In this study we aim to analyze the combined effect of age-based and gender stereotype threat on work identity processes (and in particular on authenticity and organizational identification) and on work performance (self-rating performance). The research utilizes an ample sample of over fifty-year-old workers from diverse organizations in Italy. Using a person-centered approach four clusters of workers were identified: low in both age-based and gender stereotype threat (N= 4,689), high in gender and low in age-based stereotype threat (N= 1,735), high in age-based and low in gender stereotype threat (N= 2,013) and high in both gender and age-based stereotype threat (N= 758). Gender was significantly associated with these clusters and women were more frequently present in those groups with high gender stereotype threat. ANOVA results show that workers in the last two clusters score significantly lower in authenticity, organizational identification and self-rate performance. All in all, if ageism is undoubtedly problematic for older workers’ identity processes, ageism and gender-stereotypes represent a double risk for women over fifty in the workplace. The analysis of the results can be beneficial both for the theoretical advancement and for the practical insights offered in the organizational and management field, where new policies of HR management can be elaborated, in order to value and to improve the workers experience.
Overconfidence in Understanding of How Electronic Gaming Machines Work Is Related to Positive Attitudes
Authors: Philander Kahlil S. , Gainsbury Sally M.
Published: January 2021

Previous research has demonstrated that attitudes are a primary determinant of intention to gamble on electronic gaming machines (EGMs) consistent with the Theory of Reasoned Action. This paper aims to address how biases in judgment can contribute to attitudes and subsequently behavior, including maladaptive problematic gambling behavior. We take a novel approach by viewing overconfidence in one’s understanding of how outcomes are determined on EGMs as an indication of cognitive distortions. The novelty of this paper is further increased as we compare attitudes to existing EGMs with novel EGMs which include a skill component, referred to as skill-based gaming machines (SGMs), which enables a better controlled comparison between actual and perceived skill. In Study 1, 232 US-based participants were recruited online who were shown various slot machines and SGMs and asked a series of questions about perceived skill and chance in determining outcomes to assess their understanding, then were asked their confidence in their understanding, attitudes toward the machines and they completed the Problem Gambling Severity Index. In Study 2, 246 Australian participants were recruited through community and university student samples; they attended a laboratory where they were randomly allocated to play a real EGM or SGM without money and completed the same measures as in Study 1. In Study 2, participants were randomly told that the outcomes on the machine they would play were determined entirely by chance, skill, or a mixture of both. In both studies, our findings suggest that there are more extreme values in overconfidence in how EGMs work, whereas individuals are more similar in their confidence in understanding SGMs. We also find a relationship between overconfidence in EGM understanding and positive attitudes toward EGMs, but no such relationship with SGMs. There was no impact from controlling for demographics, problem gambling severity, or labeling of machines on these relationships.
The Moral Gatekeeper: Soccer and Technology, the Case of Video Assistant Referee (VAR)
Authors: Tamir Ilan , Bar-eli Michael
Published: January 2021

Video assistant referee was officially introduced into soccer regulations in 2018, after many years in which referee errors were justified as being “part of the game.” The technology’s penetration into the soccer field was accompanied by concerns and much criticism that, to a large degree, continues to be voiced with frequency. This paper argues that, despite fierce objections and extensive criticism, VAR represents an important revision in modern professional soccer, and moreover, it completes a moral revolution in the evolution of the sport as a whole. Theoretically speaking, this technology enables an improvement in the sport’s professional standards and its public image and prestige, and especially its moral standards – Fair play. Furthermore, the introduction of this technology makes it possible to discover additional weaknesses (Standardization for extra time, a clear definition of a handball offense and more) that professional soccer regulations will probably be forced to address in the future.
Effects of an Educational Hybrid Physical Education Program on Physical Fitness, Body Composition and Sedentary and Physical Activity Times in Adolescents: The Seneb’s Enigma
Authors: Melero-Cañas David , Morales-Baños Vicente , Manzano-Sánchez David , Navarro-Ardoy Dani , Valero-Valenzuela Alfonso
Published: January 2021

Physical activity (PA), body composition and sedentary behavior may affect the health of children. Therefore, this study examined the effect of an educational hybrid physical education (PE) program on physical fitness (PF), body composition and sedentary and PA times in adolescents. A 9-month group-randomized controlled trial was conducted in 150 participants (age: 14.63 ± 1.38 years) allocated into the control group (CG,n= 37) and experimental group (EG,n= 113). Cardiorespiratory fitness, speed, strength, agility, flexibility and body mass index (BMI) were assessed through previously validated field tests. Sedentary time, PA at school and afterschool were evaluated with the Youth Activity Profile-Spain questionnaire. Significant differences were observed concerning to the CG in APA-weekend (p= 0.044), speed-agility (p= 0.005) and agility (p= 0.008). Regarding the intervention, cardiorespiratory fitness (p= 0.000), speed-agility (p= 0.000), strength (p= 0.000), flexibility (p= 0.000), agility (p= 0.000), PA in school (p= 0.011), APA-weekday (p= 0.001), APA-weekend (p= 0.000), APA-week (p= 0.000), and sedentary time (p= 0.000) increased significantly in the EG. The use of a hybrid program based on teaching personal and social responsibility and gamification strategies produced enhancements in cardiorespiratory fitness, agility, speed, APA-weekdays and APA-weekends, reducing the sedentary time.
Impact of Coronavirus Disease (COVID-19) Pandemic on Psychological Well-Being of the Pakistani General Population
Authors: Khan Adeel Ahmed , Lodhi Fahad Saqib , Rabbani Unaib , Ahmed Zeeshan , Abrar Saidul , Arshad Saamia , Irum Saadia , Khan Muhammad Imran
Published: January 2021

Background and Objectives: In order to curb the spread of coronavirus disease 2019 (COVID-19), the countries took preventive measures such as lockdown and restrictions of movements. This can lead to effects on mental health of the population. We studied the impact of COVID-19 on psychological well-being and associated factors among the Pakistani general population.

Methods: An online cross-sectional survey was conducted between 26th April and 15th May and included participants from all over the Pakistan. Attitudes and worriedness about COVID-19 pandemic were assessed using a structured questionnaire. A validated English and Urdu version of the World Health Organization Well-Being Index (WHO-5) was used to assess the well-being. Factor analysis was done to extract the attitude item domains. Logistic regression was used to assess the factors associated with poor well-being.

Results: A total of 1,756 people participated in the survey. Almost half 50% of the participants were male, and a similar proportion was employed. About 41% of the participants were dependent on financial sources other than salary. News was considered a source of fear as 72% assumed that avoiding such news may reduce the fear. About 68% of the population was worried about contracting the disease. The most common coping strategies used during lockdown were spending quality time with family, eating healthy food, adequate sleep, and talking to friends on phone. Prevalence of poor well-being was found to be 41.2%. Female gender, being unemployed, living in Sindh and Islamabad Capital Territory (ICT), fear of COVID-19, and having chronic illness were significantly associated with poor well-being. Similarly, coping strategies during lockdown (doing exercise; spending time with family; eating healthy food; having good sleep; contributing in social welfare work and spending time on hobbies) were also significantly associated with mental well-being.

Conclusion: We found a high prevalence 41.2% of poor well-being among the Pakistani general population. We also investigated risk factors of poor well-being which included female gender, unemployment, being resident of ICT and Sindh, fear, chronic illness, and absence of coping strategies. This calls for immediate action at population level in the form of targeted mass psychological support programs to improve the mental health of population during the COVID-19 crises.
Anxiety and Depression Comorbidities in Moroccan Patients With Breast Cancer
Authors: El kherchi Ouassil , Aquil Amina , El khoudri Noureddine , Mouallif Mustapha , Daghi Mohamed , Guerroumi Maroua , Saad El madani , Benider Abdellatif , Jayakumar Arumugam R. , Elgot Abdeljalil
Published: January 2021

Background: Breast cancer is the leading cause of cancer death in women worldwide with more than 1. 7 million new cases annually. Major advances have been made in the therapeutic management of this condition in many countries. However, neuropsychiatric disorders in patients with breast cancer constitute a significant concern due to their negative impact on patient's life and on the success of therapy itself.

Methodology: In this study we aimed to evaluate psychological disorders in a population of 212 Moroccan women treated for breast cancer within the Mohammed VI Center for the Treatment of Cancers of Casablanca. A questionnaire was designed to this end on the basis of different validated scales, including the Hospital Anxiety Depression Scale (HADS), the Pittsburgh Sleep Quality Index (PSQI), and the Body Image Scale (BIS).

Results: Data analysis has shown that 69.3% of participants had significant sleep disorders; 87% suffer from an anxiety-depressive syndrome (ADS), and 83.0% had significant body image dissatisfaction. A positive correlation was shown between ADS and both patients' national health insurance coverage and patients or husbands' education. Analysis further revealed that anxiety and depression were negatively correlated with different types of treatment. Similarly, both BIS and PSQI scores were positively associated with anxiety and depression disorders.

Conclusion: The present investigation highlights the need to generalize and strengthen the psychological approach of patients treated for breast cancer in Morocco. We anticipate that such a strategy will alleviate suffering and promote therapy success in these patients and will diminish or prevent conjugal and familial impacts of the illness.
Assessing the Mental Health of Fathers, Other Co-parents, and Partners in the Perinatal Period: Mixed Methods Evidence Synthesis
Authors: Darwin Zoe , Domoney Jill , Iles Jane , Bristow Florence , Siew Jasmine , Sethna Vaheshta
Published: January 2021

Introduction: Five to 10 percentage of fathers experience perinatal depression and 5–15% experience perinatal anxiety, with rates increasing when mothers are also experiencing perinatal mental health disorders. Perinatal mental illness in either parent contributes to adverse child and family outcomes. While there are increasing calls to assess the mental health of both parents, universal services (e.g., maternity) and specialist perinatal mental health services usually focus on the mother (i.e., the gestational parent). The aim of this review was to identify and synthesize evidence on the performance of mental health screening tools and the acceptability of mental health assessment, specifically in relation to fathers, other co-parents and partners in the perinatal period.

Methods: A systematic search was conducted using electronic databases (MEDLINE, PsycINFO, Maternity, and Infant Care Database and CINAHL). Articles were eligible if they included expectant or new partners, regardless of the partner's gender or relationship status. Accuracy was determined by comparison of screening tool with diagnostic interview. Acceptability was predominantly assessed through parents' and health professionals' perspectives. Narrative synthesis was applied to all elements of the review, with thematic analysis applied to the acceptability studies.

Results: Seven accuracy studies and 20 acceptability studies were included. The review identified that existing evidence focuses on resident fathers and assessing depression in universal settings. All accuracy studies assessed the Edinburgh Postnatal Depression Scale but with highly varied results. Evidence on acceptability in practice is limited to postnatal settings. Amongst both fathers and health professionals, views on assessment are mixed. Identified challenges were categorized at the individual-, practitioner- and service-level. These include: gendered perspectives on mental health; the potential to compromise support offered to mothers; practitioners' knowledge, skills, and confidence; service culture and remit; time pressures; opportunity for contact; and the need for tools, training, supervision and onward referral routes.

Conclusion: There is a paucity of published evidence on assessing the mental health of fathers, co-mothers, step-parents and other partners in the perinatal period. Whilst practitioners need to be responsive to mental health needs, further research is needed with stakeholders in a range of practice settings, with attention to ethical and practical considerations, to inform the implementation of evidence-based assessment.
Wesley LifeForce Suicide Prevention Gatekeeper Training in Australia: 6 Month Follow-Up Evaluation of Full and Half Day Community Programs
Authors: Hawgood Jacinta , Koo Yu Wen , Sveticic Jerneja , De Leo Diego , Kõlves Kairi
Published: January 2021

Background and Objective: Wesley Mission LifeForce training is an Australian suicide prevention gatekeeper program which has not been formally evaluated. The aims of this evaluation were to (1) determine the short- and medium- term impacts of the training on worker capabilities (perceived and declarative knowledge), attitudes, and reluctance to intervene measures; and (2) compare the impact of the half and full day workshops on these measures.

Method: 1,079 Australian community workers of diverse professional backgrounds completed a pre-workshop questionnaire as part of registration for the Wesley LifeForce suicide prevention training between 2017 and 2019. Of these, 299 participants also completed the post workshop questionnaires (matched sample). They attended either half day (n = 97) or full day workshops (n = 202) and completed also a 3- and 6- month follow-up questionnaire. We used linear mixed-effect modeling for repeated measures to analyze data.

Results: LifeForce training participants experienced an increase in perceived capability, declarative knowledge, more positive attitudes and reduced reluctance to intervene, at least in the short term. The program is particularly well targeted for community gatekeepers with no prior training, albeit those with prior training in this study also experienced positive and significant gains on most measured constructs.

Conclusions: We found evidence of effectiveness of the Wesley LifeForce training over time, without difference between the short (half day) and longer (full day) formats of delivery. Nevertheless, the latter format offers skills-based and skills rehearsal opportunities, the impacts of which we were unable to measure in this evaluation and should be estimated in the future.
How Do People With Intellectual Disability Engage With and Understand Gambling? A Qualitative Study of Adults in Victoria, Australia
Authors: Pitt Hannah , Thomas Samantha L. , Watson Joanne , Shuttleworth Russell , Murfitt Kevin , Balandin Susan
Published: January 2021

Objective: This study aimed to understand the factors that may influence how and why people with intellectual disability may engage in gambling.

Method: Nineteen people with intellectual disability were recruited from a disability advocacy organization and participated in face to face, semi-structured qualitative interviews. Open ended questions were used to explore participants' gambling participation, recall of, and attitudes toward, different gambling products, understanding of gambling harm, and awareness of responsible gambling messages.

Results: All participants could remember gambling in their lifetime and some participants had recently engaged in gambling. Many participants were aware of different gambling products, and a few participants could describe in detail the technical aspects of electronic gambling machines. Most participants did not specifically recall seeing gambling harm minimization messages, however some described engaging in individual responsibility measures, such as limits and control, as they perceived this reduced the risks of experiencing harm.

Conclusions: People with intellectual disability are engaging with gambling products in a similar way to the general community. Therefore, it is important to understand the different pathways that may lead people with intellectual disability to initiate and continue gambling and to ensure that they are aware of and protected from the potential risk.

Implications for Public Health: Policy makers and practitioners should seek to understand and implement a range of strategies to reduce and prevent the harms associated with particular gambling products and environments for this population sub-group.
The Persistence of Flavor: Past and Present Use of Wild Food Plants in Sierra Norte de Madrid, Spain
Authors: Aceituno-Mata Laura , Tardío Javier , Pardo-de-Santayana Manuel
Published: January 2021

Despite the increasing scientific and public interest in wild food plants, their traditional knowledge is undergoing a deep cultural erosion process at a global scale. The paper assesses past and present use of wild food plants in Sierra Norte de Madrid (Spain) in order to understand which are the main drivers of its evolution. We interviewed 132 informants and analyzed the cultural importance and present use of the following: (1) the human food use-category compared with all the other use-subcategories, (2) the food plant species, and (3) the human food use-subcategories (e.g., vegetables, fruits, condiments, or beverages). The useful wild flora included 252 plant species, of which 74 were traditionally used as human food, which is the most culturally important use-category. The most important species were three vegetables consumed cooked (Scolymus hispanicus, Bryonia dioica, andSilene vulgaris), other two greens that were eaten raw (Rumex papillarisandMontia fontana), a condiment (Thymus zygis), and a fruit (Rubus ulmifolius). Among food use-categories, vegetables was the category with a higher cultural importance index, but beverages and condiments had the lowest cultural erosion rate. We found several drivers of change in the use of wild food plants, some enhancing the trend of abandonment that affects differently certain uses and species, and others encouraging their maintenance. Factors that may explain the general erosion trend are linked to the abandonment of traditional agricultural practices and shepherding: (1) the decrease in the abundance and quality of wild food plants; (2) wild food plants are no longer necessary for subsistence; (3) the reduction of time spent in the countryside; and (4) the negative connotations of some species that are considered famine food. On the other hand, there are several motivations for gathering and using wild food plants: (1) gathering is seen as a leisure and community building activity; (2) the intense flavor of wild plants, which cannot be substituted by cultivated or commercial ones; (3) positive values associated with some species consumed as everyday food that are now considered delicatessen; and (4) the medicinal role of food, mainly food uses closer to medicine such as beverages and condiments.
Case Report: Multidisciplinary Approach for a Rare Case of Thymic Vascular Malformation
Authors: Raveglia Federico , Moneghini Laura , Cariati Maurizio , Baisi Alessandro , Guttadauro Angelo , Cioffi Ugo , Scarci Marco
Published: January 2021

We report the rare case of a 2.5 cm in size mass diagnostic for residual thymus associated with venous vascular malformation (ISSVA classification, 2008) in a 58 years old man. Diagnosis was obtained only after surgical removal that was complicated by a sudden massive bleeding (about 1,500 cc) requiring emergency conversion to median sternotomy. Difficulty in preoperative diagnosis, rarity of histologic pattern, and surgical challenges make this case very interesting for surgeons, pathologists and radiologist. Our message, dealing with mediastinal masses, is: (a) differential diagnosis between the more frequent solid antero-superior mediastinal tumors and vascular malformation should be always considered (b) preoperative angiography should always be performed in case of uncertain diagnosis (c) coil embolization should always be considered to reduce potentially fatal bleeding (d) histologic differentiation with other thymic neoplasms must be always considered.
Improved Folch Method for Liver-Fat Quantification
Authors: Mopuri Ramgopal , Kalyesubula Mugagga , Rosov Alexander , Edery Nir , Moallem Uzi , Dvir Hay
Published: January 2021

Fatty liver represents a significant metabolic pathology of excess intrahepatic fat in domestic animals and humans. Quantification of hepatic-fat content is therefore essential for diagnosis and investigation of liver and metabolic disease. However, the reproducibility of hepatic steatosis analysis is often low due to subjective and technical factors. We hypothesized that improvement in tissue-lipids extraction efficiency would contribute to the accuracy and precision of liver-fat determination. To test it, we investigated the effect of standardized tissue sonication on liver-fat quantification by the Folch method in sheep. Liver samples from grownup lambs of lean (n = 16) and fatty (n = 15) livers, and from pregnant ewes (n = 6) who died from pregnancy toxemia (PT), were used for hepatic-fat content determination with or without tissue sonication. In the grown lambs, an average hepatic-fat content of 6.6% was determined in sonicated compared to 5.1% in non-sonicated specimens (P = 0.0002). Similarly, in ewes with PT, an average of 12.5% was determined with sonication compared to 10.8% without it (P = 0.0006), and the reproducibility was higher with sonication (CV of 3.1 vs. 6.1%, respectively). Thus, tissue sonication improved the efficiency of liver-lipids extraction and was significant to the accuracy and precision of hepatic-fat determination. Enzymatic quantification of triglycerides was moderately correlated with the results obtained gravimetrically (r = 0.632, P < 0.005). The reported data provide reliable reference values for pregnancy toxemic sheep. The significant improvement in liver-fat quantification observed with the reported revised protocol is likely applicable to most mammals and humans.
Algorithmic Aspects of Some Variations of Clique Transversal and Clique Independent Sets on Graphs
Authors: Lee Chuan-Min
Published: January 2021

This paper studies the maximum-clique independence problem and some variations of the clique transversal problem such as the {k}-clique, maximum-clique, minus clique, signed clique, and k-fold clique transversal problems from algorithmic aspects for k-trees, suns, planar graphs, doubly chordal graphs, clique perfect graphs, total graphs, split graphs, line graphs, and dually chordal graphs. We give equations to compute the {k}-clique, minus clique, signed clique, and k-fold clique transversal numbers for suns, and show that the {k}-clique transversal problem is polynomial-time solvable for graphs whose clique transversal numbers equal their clique independence numbers. We also show the relationship between the signed and generalization clique problems and present NP-completeness results for the considered problems on k-trees with unbounded k, planar graphs, doubly chordal graphs, total graphs, split graphs, line graphs, and dually chordal graphs.
Alternative Protein Sources vs. GM Soybean Meal as Feedstuff for Pigs—Meat Quality and Health-Promoting Indicators
Authors: Sońta Marcin , Rekiel Anna , Więcek Justyna , Batorska Martyna , Puppel Kamila
Published: January 2021

This study aimed to explain the possibility of partial replacement of genetically-modified soybean meal (SBM GM) with pea seeds and rapeseed meal (RSM) in complete feed mixtures for growing-finishing pigs and to determine its impact on meat quality and health-promoting indices. The pigs (n = 50) were randomly divided into five groups, 10 animals each (gilts and barrows, 1:1, 3-breed: ♀ (landrace × yorkshire) × ♂ duroc), including the control group (C) and four experimental groups (E1, E2, E3, E4), and fed complete feed mixtures. The SBM GM was the only protein source in feed mixtures for control pigs. In feed mixtures for E1–E4 groups, it was partially replaced with pea seed doses of 5.0%, 10.0%, 15.0%, and 17.5% in groups E1, E2, E3, and E4, respectively. The feed mixtures were iso-energetic and iso-protein. After completed fattening, the animals were slaughtered. M. longissimus lumborum was sampled for analyses of the chemical and physical traits. The fatty acid profile determined in intramuscular fat (IMF) was used to compute the values of the health-promoting indices. The chemical and physical characteristics of meat were comparable in all groups. The study showed a dietetically-beneficial decrease in the values of atherogenicity index (AI), thrombogenicity index (TI), and saturation (S/P) in the meat of the experimental pigs vs. control group. The values of most of the analyzed quality attributes of pork justify using alternative protein sources as partial SBM GM replacers in diets for growing-finishing pigs in sustainable animal production.
Characteristics of Downward and Upward Longwave Radiation at Athalassa, an Inland Location of the Island of Cyprus
Authors: Pashiardis Stelios , Kalogirou Soteris A.
Published: January 2021

In this study, two years of hourly longwave downward and upward irradiance measurements at Athalassa, an inland location, are used to analyze and compare them. A detailed quality control process was followed according to the suggested tests proposed by the Baseline Surface Radiation Network (BSRN) group. The criteria involved are based on physically possible, extremely rare and climatological limits. Furthermore, comparison tests were also applied between the two longwave components as well as with air and ground surface temperatures. Additionally, time consistency and persistency tests were applied. All the suspect data were excluded from the analysis. The data showed that the frequency distribution of downward longwave irradiances follows a normal distribution function, while the upward longwave follows an almost normal distribution but with a long positive tail. The annual mean daily downward longwave irradiation is 27.3 MJ m−2 and the annual mean daily upward longwave irradiation is 37.8 MJ m−2. The net longwave irradiation is always negative ranging from −5.9 to −12.1 MJ/m2. Various models were tested to estimate daylight and all day downward and upward longwave irradiances under clear-sky and all-sky conditions. For the comparison of measured and estimated values the root-mean-square errors and linear regression correlations have been used. The results of this comparison showed that Idso’s and Brunt’s models perform well, and they can be used to estimate downward longwave irradiance under clear-sky conditions. Furthermore, both models were extended to estimate the daylight downward longwave irradiance under all-sky conditions by taking into account the ratio of global to the clear-sky global solar irradiance. In this case, the RMSE of the local calibrated coefficients scheme of Idso’s model was 30.6 W m−2, while Brunt’s model showed slightly lower value (29.0 W m−2).
Cytokines and Chemokines in SARS-CoV-2 Infections—Therapeutic Strategies Targeting Cytokine Storm
Authors: Pum Alexandra , Ennemoser Maria , Adage Tiziana , Kungl Andreas J.
Published: January 2021

The recently identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, the cause of coronavirus disease (COVID-19) and the associated ongoing pandemic, frequently leads to severe respiratory distress syndrome and pneumonia with fatal consequences. Although several factors of this infection and its consequences are not completely clear, the presence and involvement of specific chemokines is undoubtedly crucial for the development and progression of COVID-19. Cytokine storm and the often-resulting cytokine release syndrome (CRS) are pathophysiological hallmarks in COVID-19 infections related to its most severe and fatal cases. In this hyperinflammatory event, chemokines and other cytokines are highly upregulated and are therefore not fulfilling their beneficial function in the host response anymore but causing harmful effects. Here, we present the recent views on the involvement of chemokines and selected cytokines in COVID-19 and the therapeutics currently in clinical development targeting or interfering with them, discussing their potentials in the treatment of COVID-19 infections.
Development of Retrofitting Solutions: Remedial Wall Ties for Masonry Enclosure Brick Walls
Authors: Rebelo Filipe , Figueiredo António , Correia Lopes Gonçalo , Ferreira Tiago Miguel , Vicente Romeu
Published: January 2021

The external envelope walls of a significant percentage of the residential building stock in Southern European countries is commonly constituted by infill masonry walls. However, thousands of square meters of this masonry wall typology presents severe issues of cracking and instability, related to the incorrect and deficient support conditions of the outer brick panel of the double-leaf wall solution. In this work, an experimental campaign divided in two phases has been performed to evaluate the effectiveness of two different remedial wall ties retrofitting techniques (Solution A and Solution B) used for double leaf horizontally hollowed clay brick masonry façades. The first phase of the experimental campaign was performed on 120 isolated specimens of horizontally hollowed clay bricks, resorting to post- and pre-NP EN 771-1 brick exemplars (that is, new and pre-existent aged bricks, respectively), as well as on 4 square wallettes, with a side length of 1.20 m, considered as representative of a real scale scenario, for evaluating the two remedial wall ties retrofitting techniques. The second phase of the experimental campaign was performed to fully characterize the different failure types as well as the slipping phenomena observed in the first phase of the experimental campaign, focusing solely on the retrofitting technique Solution B and comprises 24 tests performed on isolated specimens, resourcing to new and pre-existent aged bricks as well. The results obtained by the use of these techniques revealed an average anchorage strength value ranging from 0.25 to 2.5 kN for each tested tie-bar. Solution B reveals an increase of double of the anchorage strength value in comparison to Solution A. In this sense, the global results revealed a suitable applicability of both retrofit studied solutions.
The Hydrothermal Stability and the Properties of Non- and Strongly-Interacting Rh Species over Rh/γ, θ-Al2O3 Catalysts
Authors: Cheng Guanghao , Shen Gurong , Wang Jun , Wang Yunhao , Zhang Weibo , Wang Jianqiang , Shen Meiqing
Published: January 2021

The present work reports the effects of γ-, θ-phase of alumina on the hydrothermal stability and the properties of non- and strongly-interacting Rh species of the Rh/Al2O3 catalysts. Comparing to γ-Al2O3, θ-Al2O3 can not only reduce the amount of occluded Rh but also better stabilize Rh during hydrothermal aging treatment. When the aging time was prolonged to 70 h, all the non-interacting Rh was transformed into strongly-interacting Rh and occluded Rh. The XPS results indicated that non- and strongly-interacting Rh might exist in the form of Rh/Rh3+ and Rh4+, respectively. CO-NO reaction was chosen as a probe reaction to research more information about non- and strongly-interacting Rh. The two Rh species had similar apparent activation energy (Eapp) of 170 kJ/mol, which indicated that non- and strongly-interacting Rh follow the same reaction path. The non-interacting Rh was removed from aged samples by the acid-treated method, and obtained results showed that only 2.5% and 4.0% non-interacting Rh was maintained in aged Rh/γ-Al2O3 and Rh/θ-Al2O3.
Sustainable Synthesis of Omega-3 Fatty Acid Ethyl Esters from Monkfish Liver Oil
Authors: Aguilera-Oviedo Johanna , Yara-Varón Edinson , Torres Mercè , Canela-Garayoa Ramon , Balcells Mercè
Published: January 2021

The search for economic and sustainable sources of polyunsaturated fatty acids (PUFAs) within the framework of the circular economy is encouraged by their proven beneficial effects on health. The extraction of monkfish liver oil (MLO) for the synthesis of omega-3 ethyl esters was performed to evaluate two blending systems and four green solvents in this work. Moreover, the potential solubility of the MLO in green solvents was studied using the predictive simulation software COnductor-like Screening MOdel for Realistic Solvents (COSMO-RS). The production of ethyl esters was performed by one or two-step reactions. Novozym 435, two resting cells (Aspergillus flavus and Rhizopus oryzae) obtained in our laboratory and a mix of them were used as biocatalysts in a solvent-free system. The yields for Novozym 435, R. oryzae and A. flavus in the one-step esterification were 63, 61 and 46%, respectively. The hydrolysis step in the two-step reaction led to 83, 88 and 93% of free fatty acids (FFA) for Novozym 435, R. oryzae and A. flavus, respectively. However, Novozym 435 showed the highest yield in the esterification step (85%), followed by R. oryzae (65%) and A. flavus (41%). Moreover, selectivity of polyunsaturated fatty acids of R. oryzae lipase was evidenced as it slightly esterified docosahexaenoic acid (DHA) in all the esterification reactions tested.
Electrocatalytic Oxidation of Glucose on Boron and Nitrogen Codoped Graphene Quantum Dot Electrodes in Alkali Media
Authors: Gu Siyong , Hsieh Chien-Te , Kao Chih-Peng , Fu Chun-Chieh , Ashraf Gandomi Yasser , Juang Ruey-Shin , Kihm Kenneth David
Published: January 2021

A novel solvothermal technique has been developed in the presence of C/N/B precursor for synthesizing B-N-coped graphene quantum dots (GQDs) as non-metal electrocatalysts towards the catalytic glucose oxidation reaction (GOR). Both N-doped GQD and B-N-codoped GQD particles (~4.0 nm) possess a similar oxidation and amidation level. The B-N-codoped GQD contains a B/C ratio of 3.16 at.%, where the B dopants were formed through different bonding types (i.e., N‒B, C‒B, BC2O, and BCO2) inserted into or decorated on the GQDs. The cyclic voltammetry measurement revealed that the catalytic activity of B-N-codoped GQD catalyst is significantly higher compared to the N-doped GQDs (~20% increase). It was also shown that the GOR activity was substantially enhanced due to the synergistic effect of B and N dopants within the GQD catalysts. Based on the analysis of Tafel plots, the B-N-codoped-GQD catalyst electrode displays an ultra-high exchange current density along with a reduced Tafel slope. The application of B-N-codoped GQD electrodes significantly enhances the catalytic activity and results in facile reaction kinetics towards the glucose oxidation reaction. Accordingly, the novel design of GQD catalyst demonstrated in this work sets the stage for designing inexpensive GQD-based catalysts as an alternative for precious metal catalysts commonly used in bio-sensors, fuel cells, and other electrochemical devices.
New Glycerol Upgrading Processes
Authors: Ladero Miguel
Published: January 2021

Energy policies in the US and in the EU during the last decades have been focused on enhanced oil and gas recovery, including the so-called tertiary extraction or enhanced oil recovery (EOR), on one hand, and the development and implementation of renewable energy vectors, on the other, including biofuels as bioethanol (mainly in US and Brazil) and biodiesel (mainly in the EU) [...]
IL-33 and Superantigenic Activation of Human Lung Mast Cells Induce the Release of Angiogenic and Lymphangiogenic Factors
Authors: Cristinziano Leonardo , Poto Remo , Criscuolo Gjada , Ferrara Anne Lise , Galdiero Maria Rosaria , Modestino Luca , Loffredo Stefania , de Paulis Amato , Marone Gianni , Spadaro Giuseppe , Varricchi Gilda
Published: January 2021

Human lung mast cells (HLMCs) express the high-affinity receptor FcεRI for IgE and are strategically located in different compartments of human lung, where they play a role in several inflammatory disorders and cancer. Immunoglobulin superantigens (e.g., protein A of Staphylococcus aureus and protein L of Peptostreptococcus magnus) bind to the variable regions of either the heavy (VH3) or light chain (κ) of IgE. IL-33 is a cytokine expressed by epithelial cells that exerts pleiotropic functions in the lung. The present study investigated whether immunoglobulin superantigens protein A and protein L and IL-33 caused the release of inflammatory (histamine), angiogenic (VEGF-A) and lymphangiogenic (VEGF-C) factors from HLMCs. The results show that protein A and protein L induced the rapid (30 min) release of preformed histamine from HLMCs. By contrast, IL-33 did not induce the release of histamine from lung mast cells. Prolonged incubation (12 h) of HLMCs with superantigens and IL-33 induced the release of VEGF-A and VEGF-C. Preincubation with IL-33 potentiated the superantigenic release of histamine, angiogenic and lymphangiogenic factors from HLMCs. Our results suggest that IL-33 might enhance the inflammatory, angiogenic and lymphangiogenic activities of lung mast cells in pulmonary disorders.
β2-Adrenergic Signaling Modulates Mitochondrial Function and Morphology in Skeletal Muscle in Response to Aerobic Exercise
Authors: Azevedo Voltarelli Vanessa , Coronado Michael , Gonçalves Fernandes Larissa , Cruz Campos Juliane , Jannig Paulo Roberto , Batista Ferreira Julio Cesar , Fajardo Giovanni , Chakur Brum Patricia , Bernstein Daniel
Published: January 2021

The molecular mechanisms underlying skeletal muscle mitochondrial adaptations induced by aerobic exercise (AE) are not fully understood. We have previously shown that AE induces mitochondrial adaptations in cardiac muscle, mediated by sympathetic stimulation. Since direct sympathetic innervation of neuromuscular junctions influences skeletal muscle homeostasis, we tested the hypothesis that β2-adrenergic receptor (β2-AR)-mediated sympathetic activation induces mitochondrial adaptations to AE in skeletal muscle. Male FVB mice were subjected to a single bout of AE on a treadmill (80% Vmax, 60 min) under β2-AR blockade with ICI 118,551 (ICI) or vehicle, and parameters of mitochondrial function and morphology/dynamics were evaluated. An acute bout of AE significantly increased maximal mitochondrial respiration in tibialis anterior (TA) isolated fiber bundles, which was prevented by β2-AR blockade. This increased mitochondrial function after AE was accompanied by a change in mitochondrial morphology towards fusion, associated with increased Mfn1 protein expression and activity. β2-AR blockade fully prevented the increase in Mfn1 activity and reduced mitochondrial elongation. To determine the mechanisms involved in mitochondrial modulation by β2-AR activation in skeletal muscle during AE, we used C2C12 myotubes, treated with the non-selective β-AR agonist isoproterenol (ISO) in the presence of the specific β2-AR antagonist ICI or during protein kinase A (PKA) and Gαi protein blockade. Our in vitro data show that β-AR activation significantly increases mitochondrial respiration in myotubes, and this response was dependent on β2-AR activation through a Gαs-PKA signaling cascade. In conclusion, we provide evidence for AE-induced β2-AR activation as a major mechanism leading to alterations in mitochondria function and morphology/dynamics. β2-AR signaling is thus a key-signaling pathway that contributes to skeletal muscle plasticity in response to exercise.
Function of the Porcine TRPC1 Gene in Myogenesis and Muscle Growth
Authors: Fu Yu , Shang Peng , Zhang Bo , Tian Xiaolong , Nie Ruixue , Zhang Ran , Zhang Hao
Published: January 2021

In animals, muscle growth is a quantitative trait controlled by multiple genes. Previously, we showed that the transient receptor potential channel 1 (TRPC1) gene was differentially expressed in muscle tissues between pig breeds with divergent growth traits base on RNA-seq. Here, we characterized TRPC1 expression profiles in different tissues and pig breeds and showed that TRPC1 was highly expressed in the muscle. We found two single nucleotide polymorphisms (SNPs) (C-1763T and C-1604T) in TRPC1 that could affect the promoter region activity and regulate pig growth rate. Functionally, we used RNAi and overexpression to illustrate that TRPC1 promotes myoblast proliferation, migration, differentiation, fusion, and muscle hypertrophy while inhibiting muscle degradation. These processes may be mediated by the activation of Wnt signaling pathways. Altogether, our results revealed that TRPC1 might promote muscle growth and development and plays a key role in Wnt-mediated myogenesis.
Is There an Association between Executive Function and Receptive Vocabulary in Bilingual Children? A Longitudinal Examination
Authors: Diaz Vanessa , Borjas Maria , Farrar M. Jeffrey
Published: January 2021

Dual language management has been proposed as the reason for bilingual children’s sometimes enhanced executive functioning (EF). We sought to identify the directionality of the relation between language proficiency and EF, using measures of receptive vocabulary, inhibitory control, and cognitive flexibility. Data were collected twice, a year apart, on 35- to 66.8-month-old bilingual (n = 41, M = 49.19 months) and monolingual preschool children (n = 37, M = 47.82 months). The longitudinal results revealed that while the monolingual children’s vocabulary at Time 1 predicted EF at Time 2, EF at Time 1 did not predict vocabulary at Time 2. In contrast, for bilingual children the relation was not present at all. The results were similar after the one-time analyses. The absence of relations between EF and language in bilinguals, while present in monolinguals, challenges the current conceptualization of the EF advantage in bilinguals, and emphasizes the need for more research on the development of bilingual children.