bluuebunny/crossref_metadata_2025 huggingface dataset:
The Homunculus in the Metaverse: Is Virtual Reality Prepared for Our SevenSenses?
Authors: Pfeiffer Thies
Published: October 2023

Sensing in the physical world differs from sensing in virtual worlds. As visualized in Penfield’s homunculus, touch and taste play a big role in physical surroundings. In contrast, the “Homunculus Metaversensis” for virtual reality would look different, reflecting the dominance of visual and auditory perception in virtual experiences facilitated by technologies like head-mounted displays. To create truly immersive experiences, touch, balance, movement, smell and taste are all relevant. While some progress has been made in haptic feedback and olfactory stimulation, advancement in these fields is still limited. Therefore, augmented reality, which combines physical and digital experiences, may be a more viable option for satisfying multiple senses in the present. However, future breakthroughs in virtual reality technology could enhance sensory experiences in the metaverse.
Drought stress-induced Picea abies transcriptome changes in the context of functional interactions
Authors: Mader Malte , Liesebach Heike , Kersten Birgit
Published: October 2023

Molecular responses to drought stress have been mainly studied in deciduous tree species although conifers dominate boreal forests. Here, we analysed the transcriptional response of Picea abies (L.) H. Karst. needles after exposure to severe drought by quantitative RNA-sequencing. In total, 2,402 differentially expressed genes (DEGs) were identified, of which 1,186 were up- and 1,216 downregulated. The upregulated DEGs are mainly involved in responses to stress, nitrogen compound, water deprivation, and abscisic acid as well as in channel activity. Although only one bZIP was identified among the DEGs, several other transcription factors involved in ABA-dependent pathways such as MYB, bHLH and WRKY showed differential expression. AP2/EREBP transcription factors related to ABA-independent pathways were also identified as DEGs. A functional interaction network of the 40 most connected Arabidopsis thaliana homologs of all Picea abies DEGs placed the two top-hubs P5CS1 and P5CS2 in the center. P5CS1 is the key enzyme in the biosynthesis of proline known to be accumulated in plants under abiotic stress. Lignin synthesis and DNA-related processes, among others, are overrepresented in this network. Our data highlight interesting gene targets for functional studies and natural genetic variation analyses to support the future identification and selection of potential drought tolerant trees.
Vom Ehegattensplitting zur Individualbesteuerung
Authors: Richter Wolfram F.
Published: October 2023

In Germany, married couples are taxed according to the income splitting method. This paper proposes a reform aimed at reducing the negative work incentives for the second earner. To this end, marital income splitting would be replaced by individual taxation, but only to the extent that legal maintenance obligations to the spouse are recognised as an expense for tax purposes. Under the proposal put forward here, splitting would remain permissible for low income of the primary earner, and individual taxation would only take effect for sufficiently high income of the secondary earner. In the intermediate range, a specially designed equalisation rule ensures a smooth transition of the joint tax burden.
Politik- und Marktversagen erfordern Entgeltund Rentenkorrektur
Authors: Niemeier Ernst
Published: October 2023

Pension policy with regard to statutory pension insurance can be described as a failure, at least since the Riester pension. It does not secure the standard of living and many pensioners are poor despite their pensions. In addition to a reduction in benefit levels, unemployment and significant inequality in income distribution also contribute to these developments. The author calls for compensating for this market and political failure and for raising the pension back to its original level.
Nonstandard approach to the ischemic stroke treatment
Authors: Vakhitov K. M. , Vladimirov P. A. , Zukovskaya N. V. , Kuvazhukova A. F. , Kmetik E. G.
Published: October 2023

Ischemic stroke is one of the most common causes of disability and mortality worldwide. Occlusive-stenotic lesion of the extra- and intracranial carotid arteries, which developed acutely and led to acute cerebrovascular accident, is a prognostically unfavorable factor. The appearance of endovascular technologies has revolutionized the salvation of this category of patients; however, they are sometimes powerless in the fight against nature. The article presents a case of tandem and bilateral lesions of the extra- and intracranial internal carotid artery, the successful result of treatment of which became possible only due to the development of spontaneous recanalization.
Lymphoplasmacytic lymphoma with anemia and lymphadenopathy: a case report
Authors: Yousif Hala , Alshareef Mohammed , Almaghrabi Hamzah , Fatani Wisam , Alsayed Rahaf , Alharbi Afnan , Almalki Faisal , Borhan Walaa , Altwaijry Moath
Published: October 2023

Background: An uncommon, indolent mature B-cell lymphoma called lymphoplasmacytic lymphoma (LPL) secretes monoclonal immunoglobulin M (IgM) protein in 90%-95% of cases. Non-IgM monoclonal proteins are secreted by a very tiny percentage of LPL. Patient Concerns: 67-year-old Chadi female, who was admitted to our hospital with a history of altered level of consciousness, decreased oral intake for 2 days, headache, fatigue, and palpitation for 3 years.
Case Presentation: According to the histology and immunohistochemistry of the lymph node excisional biopsy, the patient was diagnosed with malignant lymphoma consistent with LPL or Waldenstrom macroglobulinemia. Due to the high expense, the patient refused target therapy and chemotherapy in favor of merely receiving occasional transfusions as supportive care. The patient is pursuing supportive care and elective hospitalizations.
Conclusion: LPL is an extremely uncommon, sluggish illness. To further understand the clinical consequences, more research involving more patients is necessary.
Genetic Insights into Poaceae Forages: A Review of Current Marker Studies
Authors: Bayhan Bora , Baran Nurettin
Published: October 2023

Forage variety development for diversified environmental conditions may benefit from the use of genomic-based breeding procedures. In today's conditions, molecular markers are used by researchers in this field to track loci and genome regions in crop breeding studies. Although earlier characterization efforts yielded useful information, morphological traits and RAPD markers have limitations when used together for genetic diversity research. Different combinations of methodologies are required for diversified aims to study different forage species at the genetic level and to connect micro level traitsto macro level traits.
Ciudades inmateriales: un proyecto de investigación artística de Teatro para el fin del mundo
Authors: Repeto Rodríguez Irene
Published: October 2023

Artículo que aborda ejes clave del trabajo de Teatro para el fin del mundo (TFM), proyecto en el que confluyen el cuerpo, la memoria y el territorio. Desde Ciudades inmateriales, TFM propone un cruce entre la investigación y el arte, construyendo su proyecto desde el pensamiento situado en el contexto de la ruina y de espacios abandonados condicionados por la violencia. Este tipo de investigación que realiza TFM implica un teatro de riesgo, una investigación viva a partir de cuerpos pensantes, escénicos y con potencia crítica.
Palabras clave: Immaterial cities: an artistic investigation project of Theatre for the End of the World
Abstract
This article addresses the work of Theatre for the End of the World (TFM by its acronym in Spanish), a program in which body, memory and territory converge. In the project Immaterial cities, TFM merges investigation and art by means of a way of thinking grounded in contexts of ruin and abandoned spaces conditioned by violence. The research that TFM develops is a form of risk theatre, an active investigation made possible by bodies that perform with critical thinking.
Recibido: 02 de mayo de 2023 Aceptado: 14 de julio de 2023
Presentación
Authors: Amezcua Gisel , Gutiérrez Bracho Carlos
Published: October 2023

La Organización Teatral de la Universidad Veracruzana (Orteuv) es considerada la compañía más antigua de México y una de las que más han influido en la profesionalización de la actividad teatral nacional. Este 2023, celebra siete décadas de haber dado sus primeros pasos hasta convertirse en la agrupación estable y de repertorio que es hoy en día. En ella participan actores y actrices experimentados, así como jóvenes talentos de la escena xalapeña.
دور الاعلام الرياضي العراقي في الحد من الشغب لدى الجماهير الرياضية لمباريات الدوري الممتاز
Authors: فليح محمد ساهرة
Published: October 2023

دور الاعلام الرياضي العراقي في الحد من الشغب لدى الجماهير الرياضية لمباريات الدوري الممتاز وتكمن أهمية سبب اختيار موضوع الدراسة الى الحاجة الماسة الى تقليل لعنف داخل الملاعب الرياضية وبالتالي الابتعاد عن كل ما هو سلبي مما يؤثر بشكل مباشر على الرياضة العراقية وتكمن مشكلة البحث الحالي الى معرفة اهم الأسباب التي تؤدي الى حدوث اعمال شغب الرياضي داخل الملعب مما يؤثر على الاتحادات والأندية الرياضية العراقية ,يهدف البحث الحالي الى التعرف على دور الاعلام الرياضي في الحد من الشغب الرياضي من وجهة نظر رابط الجماهير . كان المجال البشري من روابط المشجعين للأندية الرياضية العراقية المشاركة في الدوري الممتاز تم التحديد لمجتمع البحث الكلي  من قبل الباحثة وهم كل من الروابط الجماهيريه لعض الأندية الرياضية  والمشاركة في الدوري الممتاز للعام 2018/2019. وقد تم اختيار عينة البحث الحالي بأحد الطرق العشوائية وهي الفرعة من اندية ( القوة الجوية , الطلبة , الزوراء ) . والبالغ عددهم (120) مشجع موزعين على الأندية الثلاث بعدد (40) مشجع استخدام الحقيبة الإحصائية spss . التوصيات :ضرورة تثقيف الجماهير الرياضية من خلال حملات التوعية البو سترات التوعوية ,العمل على تثقيف الاعبين بأهم القوانين الجديدة الخاصة لعبة كرة القدم, ضرورة ان يكون المدربين حاصلين على شهادات تدريبية عالية  AB C.
CFD Modeling of Bidirectional PMDs Inside Cryogenic Propellant Tanks Onboard Parabolic Flights
Authors: Hartwig Jason , Esser Narottama , Jain Shreykumar , Souders David , Prasad Varghese Allen , Tafuni Angelo
Published: October 2023

Future cryogenic propulsion systems will require efficient methods for transferring cryogenic propellants from a depot storage tank to a customer receiver tank to minimize costs and maximize reusability. The Reduced Gravity Cryogenic Transfer Project is currently developing advanced cryogenic fluid management technology and developing and validating new numerical models for three phases of transfer: line chill down, tank chill down, and tank fill. Additionally, multiple liquid nitrogen ([Formula: see text]) parabolic flight transfer rigs are being designed by universities and NASA to investigate the gravitational sensitivities that exist in these three technologies. To maximize the collection of low-g data during flights, it is required to extract as much [Formula: see text] as possible from the supply tank, despite variable gravity levels. The purpose of this study is to present computational fluid dynamics volume of fluid simulations of [Formula: see text] behavior in the supply tank onboard parabolic flights to validate the optimal design of a bidirectional propellant management device (PMD) using the commercial software FLOW-3D. A parametric study was conducted on the effects of gravity level, fill level, pore size, open area, thickness, and type of baffle on PMD performance. Based on the results, the designed PMD exceeded the targeted expulsion efficiency.
Recognition of Marriage by Repute: Its Implications on Customary Law and Gender Justice in Malawi
Authors: Mbano-Mweso Ngcimezile , Malunga Bernadette , Makanje Gift , Chome Theresa
Published: October 2023

Since 1995, the Constitution of Malawi has recognised marriage by repute or cohabitation as a form of marriage in the country. However, it was only in 2015 that the Marriage, Divorce and Family Relations Act formalised such a marriage by providing a criterion for courts by which the existence of the marriage can be determined. The authors argue that this Act reflects upon society by accepting this form of marriage even in traditional society. Through discourse analysis and doctrinal research methodology, the article traces how the initial concept of a valid marriage has changed to accommodate and recognise this form of marriage. Even before the statutory law had operationalised this form of marriage, traditional leaders, as a way of determining the validity of marriages, clothed these unions with some rights ordinarily attached to married people. Customary law is not static but changes over time even in a process of cross-fertilisation with statutory law, where each is culpable of being shaped and also shaping the other. The recognition of marriage by repute has changed the marriage terrain in Malawi where eighty per cent of marriages are contracted under customary law, providing gender justice for women who were initially disadvantaged when such unions were not regarded as valid marriages by not complying with formal marriage requirements in terms of custom. Such women lost all rights afforded to a wife and the necessary benefits that she would have had in a valid marriage.
Um “Choque de ordens”: uma análise sobre o controle do espaço público na orla carioca
Authors: Farias Patricia
Published: October 2023

O texto discute o papel da esfera pública e do espaço público na cidade do Rio de Janeiro, a partir da análise de políticas públicas e ações de segurança que vem sendo implementadas na orla carioca. Etnografia, observação participante e entrevistas em profundidade foram utilizadas para compor o estudo, que se estrutura sobre as percepções dos agentes públicos – guarda-vidas, guardas municipais e policiais militares – e dos freqüentadores das praias, tanto banhistas quanto trabalhadores. O foco é investigar as noções de democracia e de ordem vinculadas aos conceitos de espaço público e esfera pública alinhadas pelos diversos segmentos em questão.
Pengolahan Limbah Cair Industri Kecil Kulit Lumpia X di Kota Pontianak
Authors: Sholata Fitria , Syifa Nabilah Nur , Abshar Khairul , Apriani Isna
Published: October 2023

Industri yang ada di Kota Pontianak semakin bertambah, salah satu industri yang banyak ditemui adalah industri makanan. Selain berdampak positif, industri makanan juga memiliki dampak negatif, salah satunya adalah limbah hasil pengolahan yang menimbulkan masalah lingkungan. Salah satu industri kecil makanan di Pontianak yaitu industri kulit lumpia, limbah cair yang dihasilkan mengandung zat berbahaya yang dapat mencemari lingkungan jika tidak diolah dengan baik. Oleh karena itu, diperlukan pengolahan air limbah yang tepat untuk mengurangi dampak negatifnya terhadap lingkungan. Tujuan dari penelitian ini adalah untuk membuat rancangan dan metode alat serta untuk mengetahui efektifitas pengolahan air limbah pada industri kulit lumpia. Alat yang digunakan untuk mengurangi dampak negatif limbah dirancang dengan proses pengendapan, kombinasi filtrasi-adsorpsi dan aerasi dengan menggunakan zeolit, pasir dan busa spon sebagai media filter. Berdasarkan hasil penelitian diketahui bahwa effluen hasil pengolahan pH telah memenuhi baku mutu namun BOD dan TSS masih diatas baku mutu dengan efisiensi pengolahan -10% BOD dan 36,36% TSS sehingga diperlukan pengolahan lebih lanjut.
Analisa Partikulat Debu, SO Dan NO2 Pada Industri Manufaktur Di Surabaya
Authors: Suwanto Yudha Eka Putra , Kusuma Maritha Nilam
Published: October 2023

This study aims to determine how much dust, SO2 and NO2 concentrations are in the air and to know the description of the distribution of air in the study site. In addition, this research also aims to design air pollution control devices that can be used to control the emissions produced. The method in this research uses the Gausse method in modeling and uses AERMOD software and Google Earth to complete the model description. It is known that the farthest distance the highest concentration of dust spread is 0.071 km with a dust concentration of 101.3 µg/m3. The farthest distance the highest concentration of SO2 spread was at a distance of 0.051 km with a value of SO2 concentration of 6753.3 µg/m3. The farthest distance the highest concentration of NO2 spread was at a distance of 0.051 km with a value of NO2 concentration of 91.45 µg/m3. The air controller uses a bag filter with 6 compartments for dust control and uses silica absorbent and activated charcoal for controlling NO2 and the Flue-Gas Desulfurization (FGD) method for SO2.
Identifikasi Bahaya dan Resiko Menggunakan Metode Job Hazard Analysis (JHA) di Washing Plant Pertambangan Bauksit PT. Kurnia Jaya Raya Kabupaten Sanggau
Authors: Qutrunnada Alifia , Nirmala Azwa , Aprillia Ricka
Published: October 2023

Salah satu penyebab utama dari kecelakaan kerja dan penyakit akibat kerja yaitu kegagalan dalam mengidentifikasi atau mengenali suatu bahaya yang ada atau bahaya yang sesungguhnya dapat dihindari di tempat kerja. Pada aktivitas di washing plant PT. Kurnia Jaya Raya masih terdapat tindakan-tindakan tidak aman (unsafe acts) dan juga  kondisi-kondisi tidak aman (unsafe conditions) yang merupakan potensi penyebab terjadinya kecelakaan kerja dan penyakit akibat kerja. Terkait dengan permasalahan ini akan dilakukan penelitian yang bertujuan untuk mengindentifikasi potensi bahaya dan risiko yang terjadi pada aktivitas di washing plant, menganalisis tingkat risiko kecelakaan kerja, dan merekomendasikan upaya pengendalian. Metode yang digunakan dalam penelitian ini yaitu JHA (Job Hazard Analysis). Penelitian dimulai dengan pengambilan data primer di daerah penelitian yaitu pengidentifikasian potensi bahaya dan pengambilan data kuesioner responden. Selanjutnya ditentukan risiko consequence dan probability untuk penilaian tingkat risiko, dan rekomendasi untuk masing-masing kegiatan. Dari hasil penelitian didapatkan 21 potensi bahaya dan 31 risiko dari  3 aktivitas alat. Untuk tingkat resiko terdapat 31,25% risiko tergolong extreme dan 68,75% tergolong high. Direkomendasikan upaya pengendalian risiko bagi perusahaan ialah engineering control sebanyak 10 rekomendasi (40%), administrative control sebanyak 11 rekomendasi (44%), dan personal equipment sebanyak 4 rekomendasi (16%).
Potensi Produksi Bersih Minimasi Limbah Industri Minyak Kelapa Murni (VCO) Menjadi Herbisida Ramah Lingkungan dan Tepung Ampas Kelapa
Authors: Savika Tanti , Anisa Selvi , Jati Dian Rahayu , Apriani Isna
Published: October 2023

Minyak kelapa murni atau yang biasa dikenal dengan istilah Virgin Coconut Oil (VCO) merupakan salah satu produk turunan hasil olahan kelapa yang memiliki nilai jual tinggi karena kaya akan manfaat, sehingga industri pengolah produk ini memiliki prospek yang bagus dimasa mendatang. Proses produksi minyak kelapa murni (VCO) ini meliputi pengupasan, pemecahan tempurung kelapa, pemarutan, pembuatan santan, fermentasi, sentrifugasi, penyaringan I, vaccum drying, dan penyaringan II. Pada tiap proses produksi VCO akan menghasilkan hasil sampingan berupa limbah (padat/cair) maupun produk setengah jadi. Tujuan penelitian ini adalah untuk menganalisis potensi penerapan produksi bersih serta minimasi limbah yang dapat dilakukan pada industri tersebut. Penelitian ini menggunakan metode studi pustaka/literatur dengan cara mengumpulkan data sekunder yang berkaitan dengan penelitian untuk menganalisis produksi bersih yang dapat dilakukan. Hasil dari penerapan produksi bersih dan minimasi limbah sebagai upaya pengurangan limbah yang dihasilkan pada industri VCO yang dapat ditawarkan pada penelitian ini adalah pemanfaatan limbah air kelapa menjadi bahan tambahan pembuatan herbisida dan pembuatan tepung kelapa dari ampas kelapa.
Evaluasi Kapasitas Drainase Kelurahan Klasuur Kota Sorong Menggunakan EPA - SWMM
Authors: Yasin Azalia Fajri , Pamudjianto Agung Pamudjianto
Published: October 2023

The purpose of this research is to evaluate the condition of existing drainage channels in the area around Jalan Pulau Batanta Kompleks. In addition, it is also to determine the capacity of existing drainage channels to rainfall with a 2-year, 5-year and 10-year plan discharge. Rainfall frequency distribution analysis is carried out using the distribution analysis method, namely the Normal Distribution Method with chi-square calculations and Kolmogorov Smirnov suitability test. Rainfall intensity is calculated using the Mononobe equation and modeling with EPA-SWMM by simulating the drainage network and calculating the flood inundation area. The existing condition of the drainage system in the complex area along Jalan Batanta Island in accommodating the maximum rainfall discharge is still often overflowing, this is obtained from the results of the EPA-SWMM analysis that the channels around Jalan R.A. Kartini overflowed the most in the return periods of 2 years, 5 years, and 10 years with the largest runoff in channel 15. From the results of the evaluation of drainage channels and networks, it is known that the cause of flooding in the area around Jalan Batanta Island Complex is the existence of drainage channels that should accommodate rainwater, due to the large amount of sedimentation, as well as garbage that reduces the capacity of other channels. All channels reviewed have a sub-drainage area of 3.18 Ha with a total length of 7544.33 meters in good condition.
Encoding Protein-Ligand Interactions: Binding Affinity Prediction with Multigraph-based Modeling and Graph Convolutional Network
Authors: Mekni Nedra , Fooladi Hosein , Perricone Ugo , Langer Thierry
Published: October 2023

Machine learning models are increasingly harnessed to expedite drug discovery by effectively predicting the properties of small molecules, such as pKa, solubility, and binding affinity. While these models offer accelerated compound identification and optimization, the challenge arises when studying properties influenced by the interaction between a ligand and its corresponding protein. In response to this challenge, graph neural networks (GNNs) have emerged as a solution for integrating 3D structural data to enhance our understanding of protein-ligand interactions. Our novel model, InterGraph, introduces a unique approach to modeling protein-ligand interactions as topological multigraphs. This approach provides a comprehensive representation of the intricate spatial organization and connectivity patterns within these systems. By incorporating "interaction spheres" with varying edge densities, we capture the proximity-based influence of interactions, filtering out those occurring beyond 9 Å from the ligand, which are deemed irrelevant. Our model was trained using a ligand binding dataset from PDBbind and achieved an RMSE value of 1.34 when tested on a hold-out dataset. Our results highlight the efficacy of the multigraph in encoding the significance of close interactions, a critical factor in understanding binding affinity. On average, our model accurately predicts binding affinity values for various protein-ligand complexes and demonstrates heightened accuracy for hydrolase, lyase, and families of proteins involved in mediating protein-protein interactions. Furthermore, when compared to a set of complexes that underwent redocking calculations, the InterGraph method displayed sensitivity to the binding mode. In the context of drug discovery and development, protein-ligand interactions are pivotal in numerous biological processes. Understanding how these interactions affect biological processes is central to advancing pharmaceutical research. Binding affinity, a thermodynamic property characterizing the strength of such interactions, offers invaluable insights into these intricate processes.
Testing the stability of Neural Network Potentials for free energy calculations
Authors: Tkaczyk Sara , Karwounopoulos Johannes , Schöller Andreas , Woodcock H. Lee , Langer Thierry , Boresch Stefan , Wieder Marcus
Published: October 2023

To achieve chemical accuracy in free energy calculations, it is necessary to accurately describe the system's potential energy surface and efficiently sample configurations from its Boltzmann distribution. While neural network potentials (NNPs) have shown significantly higher accuracy than classical molecular mechanics (MM) force fields, they have limited range of applicability and are significantly slower than MM potentials, often by orders of magnitude. To address this challenge, Rufa et al suggested a two-stage approach that uses a fast and established MM alchemical energy protocol, followed by reweighting the results using NNPs, known as endstate correction or indirect free energy calculation. In this study, we systematically investigate the accuracy, robustness, and efficiency of free energy calculations between a MM reference and a neural network target potential (ANI-2x) using free energy perturbation (FEP) and non-equilibrium (NEQ) switching simulation in vacuum. We investigate the influence of longer switching lengths and the impact of slow degrees of freedom on outliers in the work distribution. We compare the results to multistage equilibrium free energy calculations (MFES) for an established dataset. Our results demonstrate that free energy calculations between NNPs and MM potentials should not be performed using FEP but require NEQ switching simulations to obtain accurate free energy estimates. NEQ switching simulations between MM and NNPs are highly efficient, robust, and trivial to implement.
Sustainability of Higher Education in Emergencies: The Case of Turkey
Authors: ERDEMİR Burcu
Published: October 2023

The COVID-19 pandemic had devastating effects on higher education systems and necessitated policymakers to take immediate measures. While this period is an opportunity to correct imperfections in higher education systems, it is also a challenge in terms of planning new policies that necessitate digitalized equipment and personnel support that increased due to the pandemic. The study aims to examine which factors of higher education learning communities can help sustain higher education institutions during and beyond emergencies. Based on a qualitative study presenting views of Turkish faculty, major findings reflect the key components of higher education learning communities. These were spotted as; ‘democratic and collaborative environments that target equitable student access to education, student success, as well as faculty professional development and well-being of faculty and students and examined through the lenses of critical pedagogy and transformational theory. Apart from the suggestions of the participants for sustainability, the author also presented some immediate-to-long-term policy suggestions for higher education decision-makers that prioritize equity, accountability, and quality, and the main principles of learning communities as collaboration and democracy, all of which are also important concepts for further development of society.
Nöropazarlama Kavramı Üzerine İçerik Analizi Çalışması
Authors: YAZICIOĞLU Yunus , TOROS NTAPIAPIS Nihal
Published: October 2023

Son yıllarda nörogörüntülemede yaşanan gelişmeler birçok alanda olduğu gibi pazarlama alanında da benimsenmiş ve nöropazarlama kavramı ortaya çıkmıştır. Nöropazarlama kısaca nörogörüntüleme tekniklerinin pazar araştırmalarına uygulanması olarak tanımlanabilir. Çalışma kapsamında; nöropazarlama alanında literatürde ulaşılabilen kaynaklar çerçevesinde şimdiye kadar Türkiye’de yapılan Yüksek Lisans ve Doktora tezlerini kapsayan bir içerik analiz çalışması oluşturulmuştur. Anlam karmaşası oluşturmamak ve analizi ön plana çıkarabilmek adına nöropazarlama kavramının detaylı irdelenmesi çalışmada ele alınan ve ekler kısmında belirtilen çalışmalara bırakılmıştır. Bununla beraber mevcut durumu ortaya koymak, akademik çalışmalarda nöropazarlamaya verilen önemi belirtmek, gelecekteki nöropazarlama araştırmalarına yön tayin etmeye katkı sağlamak amaçlanmıştır. Aynı zamanda bu çalışma, nöropazarlama alanında bu kapsamda yapılan ilk literatür taraması olma özelliğini de taşımaktadır. Konu ile ilgili 76 yüksek lisans, 21 doktora tezi bulunmuş ve çalışmaya dâhil edilmiştir. Araştırma sonucunda; uygulamalı çalışmalar içerisinde farklı alanlara yönelerek farklı disiplinlerle ortak çalışmalar yürütülebilir.
KONSERVASI ISLAM SEBAGAI ASAS BERKARYA PRODI PENDIDIKAN SENI RUPA UNISMUH
Authors: Ashari Meisar , Mukaddas Andi Baetal
Published: October 2023

This research aims to explain the implementation of Islamic values as educational principles in creating fine arts in the Fine Arts Education study program, Faculty of Teacher Training and Education, Muhammadiyah University of Makassar. The type of research used is qualitative-explanatory research, which provides an explanation of why the fine arts education study program uses Islamic values as an educational and teaching concept. Furthermore, the results of this research show that the only fine arts education study program within the scope of Muhammadiyah Higher Education in Indonesia is at Muhammadiyah University of Makassar. So that artistic practice in producing works of fine art is based on Islamic Kemuhammadiyahan values. The concept of application in education and teaching is demonstrated through the curriculum, art creation and study studies, research and community service as well as the achievement of graduate profiles. In the aspect of creating fine arts, the orientation of the work always uses ethics, content and context based on Islamic Muhammadiyah
TECNOLOGIAS EM SAÚDE E PREVENÇÃO DE INCAPACIDADES FÍSICAS POR HANSENÍASE: REVISÃO INTEGRATIVA
Authors: Candido Stephany Costa Novo , Almeida Priscilla Dantas
Published: October 2023

Introduction: Leprosy is of significant public health concern as it is an infectious and chronic disease with the potential to cause physical disabilities. Aim: To identify health technologies in scientific literature for preventing physical disabilities caused by leprosy. Outlining: This is an integrative literature review, based on the research question: "What health technologies are applied to prevent physical disabilities caused by leprosy?" formulated using the PICo strategy, where "P" stands for Population (leprosy), "I" for phenomenon of Interest (technologies), and "Co" for Context of the study (prevention of physical disabilities). Results: Eleven articles published between 2001 and 2020 in Brazil were included. More than seventy technologies were identified for use in disability prevention. The primary types of health technologies for preventing physical disabilities include strategies and materials such as lectures, home visits, and establishing a strong relationship between healthcare professionals and patients. Implications: It was identified that in the context of preventing physical disabilities caused by leprosy, assistive technology (assessment of physical disabilities, wound care, and immobilization, among others); educational technology (such as guidance on hygiene and proper medication use); and managerial technology (clinical meetings, for example) play crucial roles.
Características clínico-epidemiológicas e abordagem em pacientes politraumatizados com desfecho fatal, Hospital General IESS, Quevedo-Ecuador 2019-2020
Authors: Pazmiño Chancay Manuel Jesús , Solis Castro María Edith
Published: October 2023

La (OMS) Organización Mundial de la Salud, define como politraumatismo, aquella lesión ocasionada al cuerpo humano de tipo intencional y no intencional que se percibe de diferentes exposiciones sean agudas o graves con un impacto brusco de energía en un hecho o suceso, de aquí se produce un traumatismo severo o agudo con lesiones que perjudican el sistema respiratorio, neurológico y circulatorio. La investigación es de tipo inductivo, con enfoque cuantitativo, de tipo descriptivo, observacional y retrospectivo. El diseño del estudio es de serie de casos donde se observará y registrará los diferentes hechos en los pacientes politraumatizados atendidos con desenlace fatal en el Hospital General IESS de la ciudad de Quevedo-Ecuador año 2019-2020. Se identificó que las características clínicas en pacientes politraumatizados con desenlace fatal en el Hospital General IESS Quevedo en el período 2019-2020, presentaron signos vitales, prevaleciendo un 100% con traumas y heridas de partes blandas, de aquí se identificaron un 83% con trauma encéfalo-craneal y un 65% con obstrucción respiratoria, otras características identificadas fueron que según el tipo de traumatismo, existieron altos índices con traumatismo craneoencefálico con un 83%, traumatismo abdominal en los diferentes órganos con 76% y traumatismo torácico con un 70%.
Anemia de Fanconi. Características clínicas
Authors: Sanmartin Matute Nube Beatríz
Published: October 2023

La anemia de Fanconi es un trastorno multisistémico determinado genéticamente, una rara patología autosómica recesiva asociada con defectos en la función de reparación del ADN debido a 22 factores que se han identificado hasta la fecha como que tienen un impacto en el proceso de reparación. Es causada por mutaciones en al menos uno de los genes y se asocia con pancitopenia progresiva, aplasia de la médula ósea, diversas malformaciones congénitas y una importante predisposición a enfermedades hematológicas y tumores sólidos. El propósito de este estudio fue realizar una búsqueda bibliográfica utilizando un enfoque de revisión que incluyó criterios de calidad desarrollados en cinco etapas. Los resultados obtenidos incluyen una definición actualizada de la anemia de Fanconi, una breve referencia a su fisiopatología, signos y síntomas, y una referencia más detallada a las características clínicas y fenotípicas de la enfermedad. Brevemente, las características clínicas de la FA son diversas pero esencialmente relacionadas con la fragilidad cromosómica, la pancitopenia progresiva con insuficiencia de la médula ósea, los síndromes mielodisplásicos, la leucemia mieloide aguda, diversas malformaciones congénitas y el desarrollo de tumores sólidos o relacionados con la tendencia de los tumores sanguíneos. Las características fenotípicas pueden incluir cuatro categorías: defectos o anomalías congénitas; trastornos endocrinos y trastornos del crecimiento; manifestaciones o anomalías hematológicas; y tumores sólidos.
Recursos educativos digitales para la educación universitaria
Authors: Montecé Seixas Ernesto Ricardo , Suárez Acebo Ery Diógenes , Vega Núques María Elena , Loor Albán Jesús Salvador
Published: October 2023

En la actualidad, el proceso educativo es uno de los más cambiantes en todo el mundo, dado el avance tecnológico y las demandas de la globalización. En este sentido, existe una gran responsabilidad por parte de las instituciones educativas por formar y egresar profesionales preparados para el entorno actual y venidero. Las estrategias de aprendizaje y enseñanza deben estar a la par de esta era digital, de manera que cubra los diferentes desafíos y oportunidades del mundo digital. Los recursos educativos digitales surgen como una respuesta a esta demanda global. En consecuencia, el objetivo de la presente investigación consiste en plasmar las generalidades de los recursos educativos digitales en la educación universitaria. El enfoque metodológico de la investigación es una revisión bibliográfico – documental, apoyado por diversas bases de datos, para la obtención de información relevante en base al tema de estudio. La implementación de recursos en la educación universitaria ofrece innumerables ventajas entre las que se encuentran su capacidad para motivar al estudiante, para acercarlo a la comprensión de procesos y facilitar el autoaprendizaje a su propio ritmo, tiempo y espacio. Sin embargo, no se encuentra exenta de retos entre los que se pueden destacar la resistencia al cambio, la falta de formación y la brecha digital. Los desafíos pueden superarse con una planificación, apoyo e inversión adecuados, y lograr el fin último, que las universidades ofrezcan una experiencia de aprendizaje más atractiva y eficaz para todos los estudiantes, preparándolos para el éxito en la era digital.
Papel de la epigenética en el origen del autismo
Authors: Castillo Batista Mayelin , Ortega Rodríguez Danais Anniemari , Ortega Pow-Hing Gipsy Paola
Published: October 2023

Es bien sabido que la genética es un componente vinculado con la etiología del autismo, no obstante, la epigenética también se considera un factor asociado. El trastorno del espectro autista (TEA) o autismo es una dificultad del desarrollo que se origina por diferencias en el cerebro, generando problemas con la comunicación, además de la interacción social, y conductas o intereses restrictivos o repetitivos. El crecimiento de la población autista va en aumento acelerado, presentándose en la actualidad en 1 de cada 100 niños. Hasta la fecha se desconoce con exactitud la causa de este trastorno, sin embargo, se ha vinculado con un origen genético, biológico y, más recientemente, con la interacción entre los genes y el ambiente. El propósito de la presente investigación consiste en revisar y plasmar el papel que juega la epigenética en el origen del autismo. El enfoque metodológico de la investigación es una revisión bibliográfico – documental. Los mecanismos epigenéticos moleculares como la metilación del ADN, la modificación de histonas y el ARN no codificante, pueden causar variantes genéticas en el genoma, y han sido vinculadas con el origen del autismo. Así mismo, podrían influir factores ambientales tales como las infecciones virales, la deficiencia de zinc durante el embarazo, una edad avanzada de los padres, el sexo masculino, el déficit de vitaminas, la disfunción tiroidea materna, algunos fármacos agonistas del receptor β-2-adrenérgico en el embarazo, y la exposición prenatal al alcohol. Otro factor asociado, cuyos estudios han cobrado fuerza más recientemente es la contaminación ambiental.
Una experiencia de las TIC en las aulas virtuales
Authors: Sarmiento Montoya Lilia Maria , Cortez Macias Leyber Daniel , Moreira Santos María Genoveva
Published: October 2023

El uso de la tecnología en la educación se ha convertido en un instrumento de gran valor para la preparación, motivación e interés de estudiantes y docentes. Esto ha colaborado y fortalecido el desarrollo de las diferentes habilidades profesionales, la adquisición de conocimientos y herramientas novedosas de trabajo, que permiten nuevos proceso enseñanza y aprendizaje. En este sentido, nacen las aulas virtuales, como aquellos espacios digitalizados donde el docente dirige el proceso de educación y donde los estudiantes participan activamente, adaptando el sistema de estudio a sus propias necesidades. Esta modalidad virtual de enseñanza representa la oportunidad de ofrecer un servicio que se corresponde con las exigencias de la educación mundial y con el desarrollo tecnológico. En consecuencia, el propósito de la presente investigación es plasmar los aspectos generales del uso de las TIC en las aulas virtuales. En razón de ello, se decidió que el estudio se adelantara en base a un diseño bibliográfico y una metodología de revisión, mediante el cual se fue seleccionando artículos de interés científico académico, así como también otras clases de documentos formales. En la revisión se encontró que las tanto las TIC como las aulas virtuales, son herramientas, cuyo resultado depende de la organización, formación docente, adaptación curricular, orientación, motivación y seguimiento de los estudiantes, iguales oportunidades de acceso a internet, entre otras. Entre sus principales ventajas se encuentran romper barreras geográficas, adaptación del horario a conveniencia, revisión y participación en la producción de material, motivación, trabajo en equipo, entre otros. No obstante, se encontraron grandes desafíos como la disparidad entre poblaciones en el acceso al internet, la falta de formación profesional y adaptación curricular. Dentro de las experiencias, el uso de las aulas virtuales y las herramientas que las TIC ponen a disposición ha mejorado el resultado de la educación en términos de simplificación de los procesos, adaptación del espacio al estudiante y una mayor motivación, además de habituarse al uso de estas plataformas cada vez más usadas y presentes en las distintas fases de la educación.
Estudio de la fuerza adhesiva del silano autocondicionante para cerámicas vítreas odontológica. Revisión teórica
Authors: Obando Piedra Juan Carlos , Delgado Gaete Bolívar Andrés
Published: October 2023

Objetivo: Estudiar la fuerza adhesiva del silano auto acondicionante en un solo paso, sobre cerámicas de vidrio ácido sensibles, a través de una revisión teórica. Materiales y métodos: Es una revisión teórica, donde se efectuó la búsqueda de artículos publicados entre enero 2018 y junio 2023 en los motores PudMed, Scielo y ScienceDirect, se utilizaron las palabras claves: cerámica de vidrio, fuerza de adhesión, fuerza de unión, ácido fluorhídrico, silano, agente de acoplamiento de silano, adhesivos, Monobond Etch & Prime (MEP), en el idioma inglés y español, donde se obtuvo información sobre la acción de la fuerza de adhesión, tratamiento superficial, tamaño de la muestra, envejecimiento, tipo de prueba y de vitrocerámica. Resultados: En la búsqueda se evidenció un total de 289 artículos, de los cuales 23 estudios cumplieron con los criterios investigativos, la mayoría fue de tipo In Vitro, donde utilizaron bloques de disilicato de litio para CAD/CAM, identificaron la fuerza adhesiva o de unión a través de la prueba de resistencia de corte/microcorte (máquina de prueba universal) y consideraron el envejecimiento artificial con un dispositivo de termociclado entre 500 ciclos a 20000 ciclos (5 ºC- 55 ºC), donde 14 artículos (61%) confirman un comportamiento de la fuerza de adhesiva favorable del MEP a las cerámicas de vidrio y el 39% de los estudios reportan valores de fuerza de unión del ácido fluorhídrico + Silano (HF+S) superior al MEP en cerámicas. Conclusión: La capacidad de adhesión del silano auto acondicionante en cerámica vítrea es similar al método de acondicionamiento de porcelana vítrea de dos pasos; todavía es incierto el efecto sobre el envejecimiento en la fuerza de unión del MEP con cerámica de disilicato de litio, con esta información se puede brindar otra alternativa al ácido fluorhídrico + Silano.
Automated control of thermal vacuum impregnation and swelling of oil- and gasoline-resistant elastomers
Authors: Filippenko N. G.
Published: October 2023

Polymeric materials used in the rolling stock are currently subject to increased requirements for durability. We present a method for accelerated and automated rapid analysis of the impregnation of polymeric materials used in various aggressive environments to determine their service life as sealing products. The results of studying changes in the physical and mechanical properties of samples are given on the example of elastomeric materials used as separating and sealing materials made of oil- and petrol resistant rubber MBS-S. Hydrocarbons based on mineral oil products with different viscosity coefficients were used as working media. It is shown that the time of impregnation of the MBS-S polymer, spent on testing according to the standard method, exceeds more than 10 times the standard terms rated for repair and maintenance. Tests using the developed express filling unit showed a reduction of the impregnation time to a level acceptable in production. The derived mathematical dependences for the process of filling MBS-S oil and petrol resistant rubber with a standard working fluid and automation of filling control make it possible to predict changes in the resistance of polymeric materials. The results obtained can be used in developing database of the swelling dynamics for various materials and predicting the service life of polymers in an aggressive environment of various etiology.
Evolution of technical diagnostics in the academic and industrial laboratories
Authors: Makhutov N. A.
Published: October 2023

To the 85 anniversary of the Mechanical Engineering Research Institute of the Russian Academy of Sciences
Analysis of the cyclic strength of technical systems in conditions of complex operation loading
Authors: Makhutov N. A. , Gadenin M. M. , Yudina O. N.
Published: October 2023

The main cyclic thermomechanical loads, as well as changeable in time vibration and aerohydrodynamic loadings accompanying them affect modern energy facilities, space, air, water and ground transport. At the same time the total number of loading cycles taking into account the duration of service turns out to be within in very wide limits. It is shown that a general spectrum of loads changing in time which affect the aforementioned objects is very complicated in terms of load levels, frequency ratios and time of their action. Taking into account a large variation of service impacts in the loading levels, frequency ratio and total number of loading cycles we performed a generalized analysis of the resistance to deformation, damage and fracture of high-loaded objects of modern technics. The results obtained revealed that in conditions of combined mechanical, vibration and aero-, gidro-, acoustic loadings the limit state (by criteria of cyclic strength using the rule of linear summation of damages expressed in deformation parameters) will be attained earlier, than that obtained only with allowance of the main thermomechanical loading. To substantiate the strength and service life of the objects under consideration, traditional standard and unified mechanical isothermal tests for static and cyclic loading are carried out to determine the basic characteristics of the mechanical properties of the material, as well as special mechanical programmed tests with variable modes that simulate complex processes of operational thermomechanical, vibration and aerohydrodynamic impacts. The results of testing are taken into account in computation and experimental estimations of the strength and the fatigue life for the corresponding spectra of operational loads. A refined verification calculation of the cyclic strength and durability is becoming increasingly relevant for modern machines and units operating under conditions of increasing speeds of movement, operating pressures with increased levels of pulsations, as well as in the occurrence of accompanying mechanical oscillations, vibrations and aerohydroacoustic impacts.
Biologi Reproduksi Rajungan Angin (Podophthalamus vigil) Di Selat Tiworo Bagian Barat, Konawe Selatan, Sulawesi Tenggara
Authors: Aswandi A Muhammad , Hamid Abdul , Kamri Syamsul
Published: October 2023

Penelitian ini bertujuan untuk mengetahui biologi reproduksi (rasio kelamin, tingkat kematangan gonad, fekunditas dan ukuran  pertama  matang  kelamin)  rajungan angin (Podophthalmus vigil)  di Selat Tiworo bagian barat.  SampelP.vigil diperoleh dari hasil tangkapan sampingan nelayan rajungan dengan menggunakan bubu lipat. Setiap sampel yang diperoleh diidentifikasi jenis kelaminnya, diukur lebar karapas dan bobot tubuhnya. Rasio kelamin dianalisis menggunakan uji Chi-square (p<0,05). Perkembangan tingkat kematangan gonad diamati dariperubahanmorfologi dan warna gonad.Fekunditas rajungan dihitung menggunakan metode gravimetrik. Hasil penelitian diperoleh rasio kelamin sebesar 1:4,09 yang menunjukkan tidak seimbang antara jantan dan betina. Perkembangan gonadP. vigiljantan didominasi oleh belum matang gonad, sedangkan betina didominasi yang matang gonad. FekunditasP. vigil berkisar 415.644-3.466.290 butir, dan ukuran pertama matang kelaminbetina 92,29 mm.