bluuebunny/crossref_metadata_2025 huggingface dataset:
Evaluation of the relationship between the eighth edition of TNM staging, the mMasoaka, and World Health Organization histopathological classification for thymoma
Authors: Sert Fatma , Balci Beril , Ergonul Ayse Gul , Yalman Deniz , Ozkok Serdar
Published: October 2022

Aim of Study:

The aim of this study was to describe the correlation between the eighth tumor, node, and metastasis (TNM), mMasaoka staging, and the World Health Organization (WHO) histopathologic classification and to identify prognostic values in predicting survival and recurrence of thymoma.

Materials and Methods:

Medical files of 90 patients with thymoma diagnosed between 1992 and 2018 were evaluated for this trial.

Results:

The distributions of patients were similar between mMasaoka and eighth TNM staging according to early (I, II) and advanced stages (IIIA, IIIB, IV). Interestingly, 55 of 63 stage I patients with TNM staging showed difference as 31 of them up-staged to stage IIA and 24 of them up-staged to stage IIB in mMasoaka staging. Both staging systems closely correlated with WHO classification (p < 0.001); stages I and II were associated with low-risk groups (type A, AB, B1), and stages III and IV were associated with high-risk groups (type B2, B3). WHO classification was not a prognostic factor for overall survival (OS) (P = 0.13) and progression-free survival (PFS) (p = 0.08), but it was a prognostic factor for 10-year cancer-specific survival (CSS) (p = 0.04). Myasthenia gravis was associated to early stages (stage I, II) (p = 0.007) and related with better prognosis.

Conclusions:

Our study showed a correlation between both staging system and WHO classification. A certain difference was found between eighth TNM staging and the mMasoaka staging in terms of stage I disease. Both staging systems effectively prognosticated OS, CSS, and PFS. To clarify the prognostic relevance and clinical usefulness of the WHO classification may be beneficial in clinical practice for the treatment decision.
Understanding the Intransigence of Malaria in Malawi
Authors: Cohee Lauren M. , Goupeyou-Youmsi Jessy , Seydel Karl B. , Mangani Charles , Ntenda Peter , Sixpence Alick , Mbewe Rex B. , Matengeni Alfred , Takala-Harrison Shannon , Walker Edward D. , Wilson Mark L. , Mzilahowa Themba , Laufer Miriam K. , Valim Clarissa , Taylor Terrie E. , Mathanga Don P.
Published: October 2022

Despite the scale-up of interventions against malaria over the past decade, this disease remains a leading threat to health in Malawi. To evaluate the epidemiology of both Plasmodium falciparum infection and malaria disease, the Malawi International Center of Excellence for Malaria Research (ICEMR) has developed and implemented diverse and robust surveillance and research projects. Descriptive studies in ICEMR Phase 1 increased our understanding of the declining effectiveness of long-lasting insecticidal nets (LLINs), the role of school-age children in malaria parasite transmission, and the complexity of host–parasite interactions leading to disease. These findings informed the design of ICEMR Phase 2 to test hypotheses about LLIN use and effectiveness, vector resistance to insecticides, demographic targets of malaria control, patterns and causes of asymptomatic to life-threatening disease, and the impacts of RTS,S vaccination plus piperonyl butoxide-treated LLINs on infection and disease in young children. These investigations are helping us to understand mosquito-to-human and human-to-mosquito transmission in the context of Malawi's intransigent malaria problem.
East Africa International Center of Excellence for Malaria Research: Summary of Key Research Findings
Authors: Nankabirwa Joaniter I. , Rek John , Arinaitwe Emmanuel , Namuganga Jane Frances , Nsobya Sam L. , Asua Victor , Mawejje Henry D. , Epstein Adrienne , Greenhouse Bryan , Rodriguez-Barraquer Isabel , Briggs Jessica , Krezanoski Paul J. , Rosenthal Philip J. , Conrad Melissa , Smith David , Staedke Sarah G. , Drakeley Chris , Bousema Teun , Andolina Chiara , Donnelly Martin J. , Kamya Moses R. , Dorsey Grant
Published: October 2022

The Program for Resistance, Immunology, Surveillance, and Modeling of Malaria (PRISM) has been conducting malaria research in Uganda since 2010 to improve the understanding of the disease and measure the impact of population-level control interventions in the country. Here, we will summarize key research findings from a series of studies addressing routine health facility-based surveillance, comprehensive cohort studies, studies of the molecular epidemiology, and transmission of malaria, evaluation of antimalarial drug efficacy, and resistance across the country, and assessments of insecticide resistance. Among our key findings are the following. First, we found that in historically high transmission areas of Uganda, a combination of universal distribution of long-lasting insecticidal-treated nets (LLINs) and sustained indoor residual spraying (IRS) of insecticides lowered the malaria burden greatly, but marked resurgences occurred if IRS was discontinued. Second, submicroscopic infections are common and key drivers of malaria transmission, especially in school-age children (5–15 years). Third, markers of drug resistance have changed over time, with new concerning emergence of markers predicting resistance to artemisinin antimalarials. Fourth, insecticide resistance monitoring has demonstrated high levels of resistance to pyrethroids, appreciable impact of the synergist piperonyl butoxide to pyrethroid susceptibility, emerging resistance to carbamates, and complete susceptibility of malaria vectors to organophosphates, which could have important implications for vector control interventions. Overall, PRISM has yielded a wealth of information informing researchers and policy-makers on the malaria burden and opportunities for improved malaria control and eventual elimination in Uganda. Continued studies concerning all the types of surveillance discussed above are ongoing.
Scientific Findings of the Southern and Central Africa International Center of Excellence for Malaria Research: Ten Years of Malaria Control Impact Assessments in Hypo-, Meso-, and Holoendemic Transmission Zones in Zambia and Zimbabwe
Authors: Ippolito Matthew M. , Gebhardt Mary E. , Ferriss Ellen , Schue Jessica L. , Kobayashi Tamaki , Chaponda Mike , Kabuya Jean-Bertin , Muleba Mbanga , Mburu Monicah , Matoba Japhet , Musonda Michael , Katowa Ben , Lubinda Mukuma , Hamapumbu Harry , Simubali Limonty , Mudenda Twig , Wesolowski Amy , Shields Timothy M. , Hackman Andre , Shiff Clive , Coetzee Maureen , Koekemoer Lizette L. , Munyati Shungu , Gwanzura Lovemore , Mutambu Susan , Stevenson Jennifer C. , Thuma Philip E. , Norris Douglas E. , Bailey Jeffrey A. , Juliano Jonathan J. , Chongwe Gershom , Mulenga Modest , Simulundu Edgar , Mharakurwa Sungano , Agre Peter C. , Moss William J. , _ _
Published: October 2022

For a decade, the Southern and Central Africa International Center of Excellence for Malaria Research has operated with local partners across study sites in Zambia and Zimbabwe that range from hypo- to holoendemic and vary ecologically and entomologically. The burden of malaria and the impact of control measures were assessed in longitudinal cohorts, cross-sectional surveys, passive and reactive case detection, and other observational designs that incorporated multidisciplinary scientific approaches: classical epidemiology, geospatial science, serosurveillance, parasite and mosquito genetics, and vector bionomics. Findings to date have helped elaborate the patterns and possible causes of sustained low-to-moderate transmission in southern Zambia and eastern Zimbabwe and recalcitrant high transmission and fatality in northern Zambia. Cryptic and novel mosquito vectors, asymptomatic parasite reservoirs in older children, residual parasitemia and gametocytemia after treatment, indoor residual spraying timed dyssynchronously to vector abundance, and stockouts of essential malaria commodities, all in the context of intractable rural poverty, appear to explain the persistent malaria burden despite current interventions. Ongoing studies of high-resolution transmission chains, parasite population structures, long-term malaria periodicity, and molecular entomology are further helping to lay new avenues for malaria control in southern and central Africa and similar settings.
Policy Implications of the Southern and Central Africa International Center of Excellence for Malaria Research: Ten Years of Malaria Control Impact Assessments in Hypo-, Meso-, and Holoendemic Transmission Zones in Zambia and Zimbabwe
Authors: Wesolowski Amy , Ippolito Matthew M. , Gebhardt Mary E. , Ferriss Ellen , Schue Jessica L. , Kobayashi Tamaki , Chaponda Mike , Kabuya Jean-Bertin , Muleba Mbanga , Mburu Monicah , Matoba Japhet , Musonda Michael , Katowa Ben , Lubinda Mukuma , Hamapumbu Harry , Simubali Limonty , Mudenda Twig , Shields Timothy M. , Hackman Andre , Shiff Clive , Coetzee Maureen , Koekemoer Lizette L. , Munyati Shungu , Gwanzura Lovemore , Mutambu Susan , Stevenson Jennifer C. , Thuma Philip E. , Norris Douglas E. , Bailey Jeffrey A. , Juliano Jonathan J. , Chongwe Gershom , Mulenga Modest , Simulundu Edgar , Mharakurwa Sungano , Agre Peter , Moss William J. , _ _
Published: October 2022

The International Centers of Excellence for Malaria Research (ICEMR) were established by the National Institute of Allergy and Infectious Diseases more than a decade ago to provide multidisciplinary research support to malaria control programs worldwide, operating in endemic areas and contributing technology, expertise, and ultimately policy guidance for malaria control and elimination. The Southern and Central Africa ICEMR has conducted research across three main sites in Zambia and Zimbabwe that differ in ecology, entomology, transmission intensity, and control strategies. Scientific findings led to new policies and action by the national malaria control programs and their partners in the selection of methods, materials, timing, and locations of case management and vector control. Malaria risk maps and predictive models of case detection furnished by the ICEMR informed malaria elimination programming in southern Zambia, and time series analyses of entomological and parasitological data motivated several major changes to indoor residual spray campaigns in northern Zambia. Along the Zimbabwe–Mozambique border, temporal and geospatial data are currently informing investigations into a recent resurgence of malaria. Other ICEMR findings pertaining to parasite and mosquito genetics, human behavior, and clinical epidemiology have similarly yielded immediate and long-term policy implications at each of the sites, often with generalizable conclusions. The ICEMR programs thereby provide rigorous scientific investigations and analyses to national control and elimination programs, without which the impediments to malaria control and their potential solutions would remain understudied.
East Africa International Center of Excellence for Malaria Research: Impact on Malaria Policy in Uganda
Authors: Namuganga Jane F. , Nankabirwa Joaniter I. , Maiteki-Ssebuguzi Catherine , Gonahasa Samuel , Opigo Jimmy , Staedke Sarah G. , Rutazaana Damian , Ebong Chris , Dorsey Grant , Tomko Sheena S. , Kizza Timothy , Mawejje Henry D. , Arinaitwe Emmanuel , Rosenthal Philip J. , Kamya Moses R.
Published: October 2022

Malaria is the leading cause of disease burden in sub-Saharan Africa. In 2010, the East Africa International Center of Excellence for Malaria Research, also known as the Program for Resistance, Immunology, Surveillance, and Modeling of Malaria (PRISM), was established to provide a comprehensive approach to malaria surveillance in Uganda. We instituted cohort studies and a robust malaria and entomological surveillance network at selected public health facilities that have provided a platform for monitoring trends in malaria morbidity and mortality, tracking the impact of malaria control interventions (indoor residual spraying of insecticide [IRS], use of long-lasting insecticidal nets [LLINs], and case management with artemisinin-based combination therapies [ACTs]), as well as monitoring of antimalarial drug and insecticide resistance. PRISM studies have informed Uganda’s malaria treatment policies, guided selection of LLINs for national distribution campaigns, and revealed widespread pyrethroid resistance, which led to changes in insecticides delivered through IRS. Our continuous engagement and interaction with policy makers at the Ugandan Ministry of Health have enabled PRISM to share evidence, best practices, and lessons learned with key malaria stakeholders, participate in malaria control program reviews, and contribute to malaria policy and national guidelines. Here, we present an overview of interactions between PRISM team members and Ugandan policy makers to demonstrate how PRISM’s research has influenced malaria policy and control in Uganda.
Asia-Pacific International Center of Excellence in Malaria Research: Maximizing Impact on Malaria Control Policy and Public Health in Cambodia and Papua New Guinea
Authors: Robinson Leanne J. , Laman Moses , Makita Leo , Lek Dysoley , Dori Annie , Farquhar Rachael , Vantaux Amelie , Witkowski Benoit , Karl Stephan , Mueller Ivo
Published: October 2022

The Asia-Pacific International Center of Excellence in Malaria Research (ICEMR) was funded in 2016 to conduct a coordinated set of field and in-depth biological studies in Cambodia and Papua New Guinea (PNG), in sites that span the range of transmission intensities currently found in the Asia-Pacific regions. The overall objective is to gain an understanding of key parasite, human host, and vector factors involved in maintaining transmission in the face of intensified control and elimination programs, and to develop novel approaches to identify and target residual transmission foci. In this article, we will describe how the ICEMR program was designed to address key knowledge gaps and priority areas for the malaria control programs in each country. In PNG, partners have worked together on two consecutive ICEMR grants (2009–2016 and 2017–2024) and we present a case study of the partnership and engagement approach that has led to stronger coordination of research activities and integration with program, informing country-level strategic planning and prioritization of control activities. In both settings, the ICEMR program has generated insights into transmission foci, risk factors for ongoing transmission, highlighting the hidden burden of vivax malaria, and the need for additional complementary vector control tools. Finally, we will summarize the emerging research questions and priority areas—namely surveillance, vivax malaria, new vector control tools, and community/health systems-oriented approaches—where further tool development and implementation research have been identified as being needed to guide policy.
The West Africa ICEMR Partnerships for Guiding Policy to Improve the Malaria Prevention and Control
Authors: Doumbia Seydou , Toure Mahamoudou , Sogoba Nafomon , Alifrangis Michael , Diakite Mahamadou , Diarra Ayouba , Keita Moussa , Konaté Drissa , Diawara Sory I. , Thiam Sidibé M’Baye , Keita Soumba , Tounkara Moctar , Cissé Idrissa , Sanogo Vincent , Magassa Mahamadou H. , Barry Alyssa E. , Winch Peter J. , Marker Hannah C. , Shaffer Jeffrey G. , Traoré Sékou F. , Müller Günter C. , Cui Liwang , Beier John C. , Mihigo Jules
Published: October 2022

The Mali National Malaria Control Program (NMCP) recently established a phased set of goals for eliminating malaria in Mali by 2030. Over the past decade, the scale-up of NMCP-led malaria control interventions has led to considerable progress, as evidenced by multiple malariometric indicators. The West Africa International Center of Excellence in Malaria Research (WA-ICEMR) is a multidisciplinary research program that works closely with the NMCP and its partners to address critical research needs for malaria control. This coordinated effort includes assessing the effectiveness of control interventions based on key malaria research topics, including immune status, parasite genetic diversity, insecticide and drug resistance, diagnostic accuracy, malaria vector populations and biting behaviors, and vectorial capacity. Several signature accomplishments of the WA-ICEMR include identifying changing malaria age demographic profiles, testing innovative approaches to improve control strategies, and providing regular reporting on drug and insecticide resistance status. The NMCP and WA-ICEMR partnership between the WA-ICEMR and the NMCP offers a comprehensive research platform that informs the design and implementation of malaria prevention and control research programs. These efforts build local expertise and capacity for the next generation of malaria researchers and guide local policy, which is crucial in sustaining efforts toward eliminating malaria in West Africa.
AVALIAÇÃO DOS FATORES PSICOSSOCIAIS NA ACEITAÇÃO DE TECNOLOGIA: UMA ANÁLISE DO SISTEMA ELETRÔNICO DE INFORMAÇÃO (SEI) NA POLÍCIA RODOVIÁRIA FEDERAL
Authors: Henrique Lima Faria Luiz , Valentin Cozzer Eduardo
Published: October 2022

Resumo: Os anos que se seguiram a virada do século XXI nos trouxeram um crescimento tecnológico exponencial, em especial na área de tecnologias da informação e comunicação. Estudos demonstram que fatores psicossociais exercem grande influência na aceitação de novas tecnologias pelos indivíduos. Este trabalho tem por objetivo analisar os fatores psicossociais que afetam a aceitação e uso do Sistema Eletrônico de Informação (SEI) na Polícia Rodoviária Federal. A pesquisa foi reali- zada com servidores da PRF no Estado do Espírito Santo, aplicando-se uma adaptação do modelo UTAUT (Teoria Unificada de Aceitação e Uso de Tecnologia). A metodologia examinou relações entre variáveis e testou algumas hipóteses. Os resultados mostraram que três dos construtos analisados não possuem significância suficiente para contribuir com a acurácia preditiva do modelo adaptado. São eles: Ansiedade, Autoeficá- cia e Influência Social. Entretanto é possível comprovar que os demais construtos analisados, quais sejam, Atitude, Expectativa de Esforço, Ex- pectativa de Desempenho, Condições Facilitadoras e Intenção de Uso, apresentam uma capacidade preditiva de grau moderado a substancial para o modelo, em relação à Intenção de Uso, com valor aproximado de 69%. Enquanto com relação ao Comportamento de Uso o modelo apre- senta acurácia de 27%, o que representa um grau de fraco a moderado.

Palavras-chave: aceitação de tecnologia, gestão pública, governo eletrônico.
Cami Mekânlarında Su ve Bir Algı Unsuru Olarak Müstakil Su Ögeleri
Authors: TAYILGA Gamze , DEMİRARSLAN Sibel
Published: October 2022

Su, canlılarda yaşamın devamı için bir ihtiyaç olmasının yanı sıra geçmişten günümüze pek çok kültürde kullanılagelen önemli bir öge olmuştur. İnsanın su ile olan ilişkisi toplumsal hayatın, yerleşimlerin ve dolayısıyla mimarinin etkilenmesini sağlamıştır. Su ögesi, farklı yapı türlerinde hem yapı içerisinde hem de yapılı çevrede mimari bir unsur olarak yer almıştır. İslam mimarisi ibadet yapılarında, su ögelerini merkeze alan veya ibadet mekânı içerisine dâhil eden çeşme, süs havuzu, şadırvan gibi uygulamalar yapılmıştır ve yapılmaya devam etmektedir. Durağan ve akan olmak üzere, farklı biçimlerde kullanımlarıyla su, fiziki temizlenme ile birlikte, ruhsal arınma, yenilenme, canlanma gibi mesajları da içeren; dünya hayatı ve cennet tasvirini kullanıcı zihninde canlandıran bir algı unsurudur. Bu çalışmada; cami mimarisinde bir tasarım elemanı olarak kullanılan suyun mekân içerisinde bilinçli bir şekilde algı unsuru oluşturma durumu ve algısal etkileri incelenmiştir. Osmanlı Devletinden 2022 yılına kadar olan süreçte inşa edilmiş Marmara Bölgesinde yer alan çeşitli camilerin iç mekânlarında bulunan müstakil su ögeleri örneklemi belirlenerek; biçimsel özellikleri, kullanım amaçları ve suyun fiziksel özellikleri yönüyle değerlendirilmiştir. Nitel araştırma yöntemleri kullanılarak yapılan bu araştırmada veriler, literatür ve dijital kaynak taraması yöntemi ile elde edilmiştir. Çalışmanın özgün niteliğiyle literatüre katkı sağlaması beklenmektedir.
Qualidade de vida de pessoas com deficiência auditiva atletas e não atletas
Authors: Citton Gabriel , Arossi Guilherme Anziliero , Santos Ana Maria Pujol Vieira dos
Published: October 2022

Diversos fatores podem afetar a qualidade de vida (QV) das pessoas com deficiência auditiva, e buscar compreendê-los é fundamental, pois os fazem parte de uma comunidade que possui uma língua e modos de socialização próprios. A atividade física ou o esporte desempenham um papel importante na QV, seja na prevenção de doenças, na sensação de bem-estar ou ainda permitindo relações pessoais e coletivas significativas. Diante disso, o objetivo deste estudo foi descrever a QV de atletas pessoas com deficiência auditiva praticantes da modalidade de handebol e de pessoas com deficiência auditiva não atletas. Estudo descritivo e transversal, com a amostra composta por 24 atletas da Seleção Brasileira de Handebol de Surdos, que disputaram em 2018 o Campeonato Mundial de Handebol de Surdos, e 33 indivíduos surdos não atletas. Os instrumentos utilizados foram um questionário sociodemográfico acrescido do histórico da deficiência e o WHOQOL-BREF, utilizado para avaliar a QV. Os resultados do estudo apontaram que para ambos os grupos, a classificação dos domínios da QV é regular. No contexto desta pesquisa, os atletas com deficiência auditiva perceberam a sua qualidade de vida e a satisfação com sua saúde como boa, enquanto os não atletas, como regular.
Análise cinesiológica da remada no skate e suas aplicações na Educação Física escolar
Authors: Breves Juliana Dias , Deprá Pedro Paulo , Pimentel Giuliano Gomes de Assis
Published: October 2022

O skate é uma prática corporal de aventura que constitui a cultura corporal do movimento. Na Literatura Esportiva, observa-se uma carência de investigações sobre seus movimentos básicos, principalmente em relação à remada que é sua técnica de deslocamento. O objetivo deste estudo foi descrever as fases da remada e propor um modelo de avaliação a ser utilizado nas aulas de Educação Física. A partir de uma análise cinesiológica dos movimentos de quinze voluntários realizando a remada, foi criado um checklist, que foi testado em uma Escola de Aplicação Pedagógica. Esse instrumento mostrou-se coadjuvante na prática pedagógica do professor de Educação Física.
Análisis semántico de los bloques de contenido de los currículos de la Educación Física escolar en Iberoamérica
Authors: Hernández Moreno José , Castro Núñez Ulises Sebastián , Stahringer Flores Roberto , Sgró Juan Marcelino
Published: October 2022

El objetivo del trabajo es hacer un análisis semántico de las denominaciones empleadas en los bloques de contenidos que componen los Diseños Curriculares de la Educación Física Escolar (EFE) en Iberoamérica. El trabajo se enfoca en los niveles educativos básicos y obligatorios, y su fuente de datos la componen doce autores expertos en el tema y las órdenes o decretos curriculares oficiales publicados por los veintidós países analizados. La praxiología motriz y las teorías educativas y pedagógicas usadas, constituyen el marco de referencia teórico de partida. Se entiende como análisis semántico el análisis del significado de las palabras. Se empleó una metodología de análisis de contenido y búsqueda documental. Se elaboró un sistema de trece categorías “ad hoc”, para el registro y análisis de los datos. Se realizó un análisis estadístico básico y una discusión de los datos comparando las propuestas de los currículos oficiales y las de los autores. Los resultados más significativos obtenidos son los siguientes. Los autores agrupan al 91,68% de las denominaciones en seis categorías siguientes: Acciones motrices y situaciones motrices (26,39%); Danza y expresión corporal (13.90%); Deporte-deportes (9,72%); Juego-Juego motor (13.90%); Introyección-acondicionamiento físico (11,11%) y Naturaleza-aventura-ambiental (16,66%); quedando el 8,32% para los términos de las siete categorías restantes. Con respecto a los Diseños Curriculares de los países, se observa que el 67,46% se agrupa en las cinco categorías siguientes: Danza y expresión corporal (12,05%), Deportes (15,66%), Juego-juego motor (16,26%), Habilidad o habilidades (9,64%); Introyección-acondicionamiento físico (13,85%); quedando el 32,54% para las ocho categorías restantes.
Efecto de un programa de ejercicio físico terapéutico sobre la capacidad funcional en adultos mayores
Authors: Herrera Jaureguí Luis Orlando , Bravo Polanco Eneida , Benítez González Mislaidy Caridad , Rodríguez Quintana Wilfredo , Pérez Castillo Yoel
Published: October 2022

Introducción: El estado funcional en las diferentes edades es el resultante de la interacción de los elementos biológicos, psicológicos y sociales. Es probable que constituya el reflejo más fiel de la integridad del individuo a lo largo del proceso de envejecimiento. Objetivo: Evaluar el efecto de un programa de ejercicios físicos terapéuticos sobre la capacidad funcional en un grupo de adultos mayores. Métodos: Se realizó un estudio cuasi experimental con pre y pos tratamiento en el período comprendido septiembre de 2019 - abril de 2020. Fue escogida una muestra de 50 adultos mayores pertenecientes a la Casa de Abuelos del municipio Cumanayagua con edades comprendidas entre los 60 y 80 años que cumplieron con los criterios de inclusión. Se valoró la capacidad funcional del adulto mayor mediante el Índice de Katz y para la movilidad y el equilibrio se utilizó la escala de Tinetti. Resultados: Predominó el sexo femenino (62%), y las edades comprendidas entre 66 y 70 años (34%). En las Actividades Básicas de la Vida Diaria (ABVD) después de finalizado el programa de ejercicios físicos la mayor frecuencia fue en el índice A (70%) y en la marcha y el equilibrio la categoría sin riesgo (60%). Conclusiones: Los resultados obtenidos han demostrado que el grupo de adultos mayores incorporados a un programa de ejercicios físicos terapéuticos logró ser independiente en las actividades básicas e instrumentales de la vida diaria y mejoró la capacidad funcional.
ACCIDENTS PREVENTION SYSTEM-HAIR PIN BENDS ROADS
Authors: CH.SRIKANTH  , D.LAKSHMI PRASANNA  , K.ABHILASH  , CH.AJITH KUMAR  , K.VIJAYA LAKSHMI
Published: October 2022

It is a accident prevention system which is very useful in mountain roads tutings hair pin
bends and u turns. This project is implemented using a microcontroller board .sensor and LED’s are interfaced to the microcontroller based on the vechicles then the relavantled’s will glow which alert driver about the vehicle is arriving the trun or blind spot.It reduces the accidents.Mostly,in the hill areas of accidents due to poor devploment of national hihgwayes in india the rate of accidents in ghats section is increasing day by day.
Explaining Mental Illness
Authors: Brossard Baptiste , Chandler Amy
Published: October 2022

Can the social sciences explain the emergence of mental disorders in societies or in individuals? This book presents a critical look at sociological explanations of mental illnesses, making the case for their renewal.
Boys, Childhood Domestic Abuse and Gang Involvement
Authors: Levell Jade
Published: October 2022

Previously overlooked in domestic violence and abuse policy and practice, Jade Levell offers radical insights into the lives of young boys in DVA-affected households.

Showing how boys in this context navigate their journey to manhood, including gang involvement, the book makes practice recommendations for supporting these ‘hidden victims’.
Ability of Persons Deprived of Legal Capacity to Exercise Their Personal Rights
Authors:   University of Kragujevac, Faculty of Law, Ponjavić Zoran
Published: October 2022

In spite of ratified international documents, the protection of persons with mental health problems, intellectual or physical disabilities in the legal system of the Republic of Serbia is still enforced by legal institutes such as deprivation of the legal capacity and a placing of these persons under guardianship. These legal solutions especially does not resolve a question of exercising personal rights that can be done by their holders exclusively in case they are capable of it. Since the guardian is not entitled to enforce them, it emerges that these rights do not exist for persons deprived of legal capacity. This paper endeavors to address an issue on abilities of these persons to make legally binding decisions concerning these rights. Possible solutions to the matter can be found in establishing natural capacity of these persons and through their participation in decision making to the extent that their mental and psychical condition allows. In case that these persons do not have even a minimum of capacity for decision making, the guardian must take a legally binding decision on behalf of a person deprived of legal capacity either on his own or upon the consent of a guardianship authority. Thereby certain criteria have to be taken into account so that the decision is in the best interest of the person represented.
The Changing Nature of the Right to Strike in the Republic of Serbia
Authors:   University of Kragujevac, Faculty of Law, Urdarević Bojan
Published: October 2022

The right to strike is not an absolute right according to the Constitution of Serbia, however, its dimensions are determined by a constitutional provision, which perscribes it as a right of the employees regulated either in compliance with the provisions of the law dealing with the right to strike, or by a collective agreement. Although the right to strike today belongs to the corpus of basic human rights, under certain circumstances it can be prohibited or limited by an obligation to fulfill certain conditions. A general prohibition of strikes is not in compliance with the principles of the freedom of association. However, even the international labor standards allow the possibility to either prohibit or limit the right to strike for a certain type of employees. National legislations are obliged to adjust their internal needs to limit the right to strike so as to comply with the international norms. Any venture out of the framework of internationally recognized conditions for the limitation of strike can become its opposite, a restriction on the rights of employees to exercise and protect their socio-economic rights to organize a (lawful) strike. The author reinvestigates the concepts of strikes, with a focus on Serbian legislation and most important Court decisions in this area. In addition, author analyzes most important international labour standards related to the right to strike and points out the state of the social dialogue in the republic of Serbia.
Трансабдомінальна ультразвукова діагностика непухлинних захвоювань кишківника у дорослих
Authors: Zhayvoronok М. М. , Koval O. V.
Published: October 2022

Вступ. У структурі захворювань ободової кишки переважають онкологічні захворювання, що становлять до 45% всіх хвороб кишківника. Зростання захворюваності на колоректальний рак з кожним роком відзначається практично у всіх країнах, у тому числі і в Україні. Вчасно виявлені передпухлинні захворювання кишківника, такі як дивертикули, коліти, апендажити та запальні захворювання кишківника, можуть допомогти в профілактиці колоректального раку.

Мета. Аналіз можливостей трансабдомінальної ультразвукової діагностики непухлинних захворювань кишківника.

Метріали та методи. Проведено огляд літератури та власних спостережень ультразвукового дослідження непухлинних захворювань товстої кишки.

Результати. Проаналізовано можливості трансабдомінальної ультразвукової діагностики патологічних змін кишківника, таких як дивертикулярна хвороба, коліти, апендажити, запальні захворювання кишківника, сегментарний інфаркт великого чіпця та аппендицит.

Висновки. Комплекс методик ТАУЗД кишківника є високоінформативним та неінвазивним методом діагностики в руках лікаря ультразвукової діагностики. Враховуючи швидке поширення ультразвукової апаратури, підвищення роздільної здатності датчиків, дана методика може суттєво доповнити існуючі методи діагностики захворювань кишківника. Застосування оглядової ТАУЗД дозволить виявити патологічні зміни кишківника на доклінічній та малосимптомній стадії, виключаючи при цьому вплив іонізуючого випромінювання.
Комплексний аналіз показників захворюваності на хвороби системи кровообігу військовослужбовців Збройних Сил України
Authors: Sokolyuk А. К. , Tkachuk І. М. , Tkalenko О. М.
Published: October 2022

Мета. Провести комплексний аналіз показників захворюваності військовослужбовців Збройних сил України з приводу хвороб системи кровообігу з 2016 по 2020 рр.

Матеріали та методи. Для досягнення мети вивчено показники захворюваності на хвороби системи кровообігу та їх динаміку у різного контингенту військовослужбовців з 2016 по 2020 рр.(за матеріалами звітної документації Міністерства оборони України – форма 2 МЕД – за 2016–2020 рр.).  У дослідженні застосовано методи бібліографічний, статистичний, системного підходу та аналізу. Статистична обробка проводилась з використанням програми Microsoft Excel 2007 та стандартного статистичного пакета STATISTICA 6,0.

Результати. Захворюваність з приводу хвороб системи кровообігу у військовослужбовців Збройних Сил України зросла з 48,95 ‰ в 2016 році до 64,28 ‰ в 2019 р., зі зниженням показника до 57,85 ‰ в 2020 році, з середнім темпом приросту +5,19 % (найвищі показники у військовослужбовців строкової служби +16,8 % та військовослужбовців за контрактом +8,68 %). Загалом, в структурі захворюваності на хвороби системи кровообігу військовослужбовців першу рейтингову п'ятірку ввійшли: артеріальна гіпертензія (з середньозваженим показником 47,1±10,6 %: військовослужбовців офіцерського складу 58,8±13,2 % з середнім темпом приросту +1,34 %; контрактної служби 49,2±11,2 з середнім темпом приросту +4,55 %), «інші хвороби системи кровообігу» (19,0±4,3 %), геморой (9,8±2,19 %), варикозне розширення вен нижніх кінцівок (7,1±1,59 %) та ішемічна хвороба серця (5,3±1,19 %). У військовослужбовців строкової служби спостерігається зростання середнього темпу приросту артеріальної гіпертензії (+26,5 %), ішемічної хвороби серця (+202,97  %, з них стенокардія + 29,97 %), церебро-васкулярних захворювань (+54,5 %, з них гостре порушення мозкового кровообігу +45,4 %). Виявлено збільшення темпів приросту інфаркту міокарда: у військовослужбовців контрактної служби +64,9 % та офіцерського складу +27,5 %. У всіх контингентів військовослужбовців спостерігається зростання середніх темпів приросту ревматизму (зокрема, у військовослужбовців контрактної служби +741,3 %), хоча його питома вага в структурі захворюваності на хвороби системи кровообігу невелика (0,4±0,08).

Висновки. Зростаючі показники первинної захворюваності на хвороби системи кровообігу у військовослужбовців всіх категорій, особливо строкової та контрактної служби, вимагає удосконалення медико-організаційних заходів профілактичної спрямованості в роботу лікувально-профілактичних закладів Міністерства оборони України.
Current state and development of project management in the Republic of Kazakhstan
Authors: Turkebayeva К. Т. , Sabden О. S.
Published: October 2022

Project management and project approach in order to implement the development priorities of the country and its regions have acquired a dynamic development in Kazakhstan. The project approach as an effective form of management is actively applied in the following fields: manufacturing, IT, trade, construction, tourism, consulting, financial services, education, public administration, etc. There is a significant increase in successfully implemented projects in many areas of activity. The research on the experience of project management in the organizational environment of the state bodies is currently not enough. In connection with the intensification of the implementation of project management methodology, tools, methods and mechanisms in the activities of state structures, in-depth studies of project management best practices are needed for the successful realization of national projects on a national scale. The article aims to explore the present state and development of project management in Kazakhstan, which has a significant impact on both private and public sectors. The theoretical significance of the study lies in the generalization of knowledge about the project approach application in the public administration system. The research methodology includes a theoretical review of legal acts, a retrospective, comparative analysis, methods of generalization, systematization and analogies. Regulatory legal acts, statistical data, etc. were used as an information base. Within the framework of this review, the dynamics of project management development in state bodies is described through the prism of the implementation of state programs and national projects. The normative acts on project management in state bodies are considered. The methodological foundations of the project approach, the essence and key concepts of the classical and flexible approaches to project management are presented. Problematic issues that arise in the realization of state programs and national projects are identified.
An Ayurvedic Approach to Inner Ear Diseases
Authors: Athira Rosh  , Veena Shekar
Published: October 2022

Ear is one among the sense organs, which keeps one connected to other and with the surroundings. Ear functions the conversion of sound waves into electrochemical impulses and maintains the sense of balance. In the present era, increased technology has resulted in change in lifestyle like increased use of ear phones or headsets, excessive use of mobile phones, exposure to loud noise, and modern pub culture etc which has made the ears more sensitive to many problems. This can be either hearing disorders or tinnitus or vertigo which can have an adverse effect on our lives, which remains the most challenging to treat in contemporary science. Ayurveda gives detailed explanation regarding ear diseases, where in it covers all the diseases pertaining to external as well as internal ear. Therefore, while looking into the classification of these diseases, no such explanation is given separately for Abhyantara karna rogas, but a special attention is given for the explanation of ear lobe diseases (Karna pali rogas). In this article an effort is made to understand these major inner ear problems with those of ear disorders explained in ayurveda with their specific etiology, clinical features and the management with respect to the contemporary science
Meta-Analysis of Emergencies in ENT and its Management: An Ayurvedic Approach
Authors: Dhanashree Gole  , Nilakshi Pradhan
Published: October 2022

Emergencies in ENT are common occurrence. Early diagnosis and management result in reduction in morbidity and mortality. In this study we have explained initial assessment, medical records, diagnosis on admission and outcome of emergency care. A total of patients were attended as an emergency in our institution’s hospital apart from OPD timing i.e., (9-4pm). The most common emergencies among pediatric age group were foreign body in ear, nose, and throat. The other most commonly encountered emergencies were RTA patients with cut or tear wound, epistaxis. In traditional text of Ayurveda mentioned terms like: Vegavastha Dhatugat Avastha, Upadrav, Asadhya Lakshanas, Agantuj Vyadhi, Sadhya, Ashu etc. for emergency conditions which are needed to be taken care of immediately
The ENT emergencies play a key role in the management of life-threatening conditions requiring immediate evaluation and management. It is important to prioritize the emergency/non emergency cases in order to ensure proper care is given to the emergency cases.
A Clinical Study to Evaluate the Effect of Karshyahar Yoga Granules and Ksheerbala Taila Matra Basti in Karshya w.s.r to Undernutrition in Children
Authors: Neha Vats  , Minakshi Chaudhary  , Vijay Chaudhary
Published: October 2022

Undernutrition among children is one of the serious issues prevailing in developing countries. Despite many efforts India has still higher number of incidence of undernutrition. Karshya roga mentioned in Ayurveda can be the most probable correlation of undernutrition. As Ayurveda has remarked very minute detail about concept of Brihmana and Balya which is the mainstay therapy for Karshya. Therefore we can use Ayurvedic medicine as a better alternative for the management of undernutrition. Aim: To evaluate the efficacy of Karshyahar yoga granules and Ksheerbala taila matra basti in Karshya w.s.r. to undernutrition in children. Materials and Methods: The study was conducted on 40 children of undernutrition for a period of 3 months. Clinical features (weight, height, Daurbalya etc) and hematological parameters (Hb gm%, ser. protein etc) were documented before and after treatment. Statistical Analysis Used: Observations of the study were analyzed and findings were evaluated by using statistical methods Results: In the present study 12.5% patients showed marked improvement, 42.5% patients showed moderate improvement and 45% patients showed mild improvement. No adverse effect of the trial drug was observed during the study. Conclusions: The results showed that Karshyahar yoga granules along with Ksheerbala taila matra basti is more effective in comparison to single use of Karshyahar yoga granules in the management of undernutrition in children.
Mild Pre-Eclampsia (Garbhini Shotha) in Pregnancy - A Correlational Review
Authors: Sushmita Bakale  , Shreyes S  , Yogitha Bali M.R  , Sujatha S. Patil  , Bharathi K S
Published: October 2022

Pregnancy in the life of a female is like a beautiful chapter that provides a purpose of living and makes her a complete woman simultaneously. Every female has a beautiful story of their own in their pregnancy which they cherish throughout their lifetime and nobody wants it to be life threatening. Earlier majority of the women were undergoing only the normal delivery due to their food habits and lifestyle practices. Presently C-section has dominated due to modern lifestyle practices, dietary habits and most important stress as the causative factor for the complications of pregnancy. Pre-eclampsia being one of the commonest complications during pregnancy is leading to severe morbidity and mortality. Various treatment methods are being followed for the prevention of the same in different systems of medicine. Present study was made to elucidate an in-depth literature of pre-eclampsia in ancient system of medicine called Ayurvedic science and to find the possible methods to manage the health issue. Based on the available Ayurvedic literature and the Modern, Pre-eclampsia can be correlated to Grabhashotha based on the signs and symptoms including various treatment methods.
A Clinical study to evaluate the effect of Amritadi Kwatha and Guda-Haritaki in the management of Vatarakta w.s.r. to Hyperuricemia.
Authors: Shikha  , Thakur Sunil  , Chaudhary Vijay  , Soni Manik
Published: October 2022

The present is an era of rapid modernization. Due to sedentary lifestyle and faulty dietary habits, humans are becoming more vulnerable to several metabolic disorders. Vatarakta is one of them which is caused by association of vitiated Vata Dosha and morbid Rakta Dhatu. In modern science, it resembles the symptomatology of gout which is caused by hyperuricemia. The epidemiology of hyperuricaemia is different from that of gout. Only 10% of the patients with hyperuricaemia exhibit gout. It is more common in upper social class and affects men more than women. It is a potential signal for several comorbidities like diabetes mellitus, hypertension, coronary artery disease, obesity, renal diseases etc. The purpose of this study was to find out an effective and well accepted drug with minimal or no complications for this illness. 30 patients who were diagnosed with Vatarakta w.s.r. to Hyperuricemia were allocated randomly into two groups. The test drug i.e. Amritadi Kwatha 30 ml and Guda-Haritaki 10 g was given to 15 patients of Group I and the standard drug Febuxostat 40 mg was given to 15 patients of Group II for a duration of 6 weeks. Subjective parameters were assessed before and after the completion of trial. Data obtained during the trial was tabulated and statistically analysed.
Effect of Different Dosage Form of Saindhavadiyoga in the Management of Computer Vision Syndrome: A Pilot Study
Authors: Vipul Shukla  , B. Mukhopadhyay
Published: October 2022

Eyes have a unique position among all the sense organs. Primary importance has been given for the protection of eyes by ancient Indian scholar because without eyes whole world is full of darkness. With the advancement of science development of many electronic gadgets like computer mobile etc, which has been produce new diseases. Among those diseases computer vision Syndrome is one of them. In modern system there is no permanent cure of CVS. In Ayurvedic text there is no description of Computer Vision Syndrome but it can be a Anukta vyadhi as describe by a Charak. Some of ocular symptoms of computer vision syndrome can be correlated with Sushkaksipaka as describe by Acharya sushrut and A.Hridya. Modern medicine do not have a definite treatment for this problem except lubricating eye drops whereas Ayurvedic kriyakalpas that is Ayurvedic local ocular therapies could suggest definite treatment to cure the computer vision syndrome along with the change in working style and correction of refractive error. Drugs which are describe in the treatment of Suskhakshipaka have potent property to reduce the clinical features of CVS. So in this clinical trial, I have used different dosage form of Saindhavadiyoga in the management of CVS. Study was conducted among the BHU computer professionals and all the patient were divide in the three group. In the group A eye drop and Anjana of Saindhavadi yoga was given, in the Group B only Carboxy Methyl Cellulose eye drop was given while in the group C only Tarpan therapy was given with Saindhavadighrita All the group have positive result results in reduction of signs and symptoms of CVS without any side effect which are produce by the preservative of Artificial tear drops. But in the group C have better results in comparison to other two group, it was occur due to oleation, nutritive antioxidant property of Ghrita and Yogvahi property of Ghrita which increase the bioavailbilty of drug along with other content of the drug.
Analysis on Action of Rakthasthambhaka Dravya’s in Asrigdhara with special reference to Abnormal Uterine Bleeding
Authors: Noor Fathima  , Mamatha K.V
Published: October 2022

Rakta is the main constituent in the human body as it is considered as vital. Sthambhana means to prevent mobility or block, is one among the Shadvidopakrama and can be well-thought-out as a part of Chaturvidha Chikitsa. Raktasthambhana means to stop excess flow of Rakta because Atyaadhika Raktasrava (excessive menstrual bleeding) may be life threatening so haemostatic measures should be adopted. Asrigdhara defined as excessive and prolonged bleeding during menstruation with or without intermenstrual bleeding. The Nidana’s leading to vitiation of Tridosha’s in Garbhashaya Gata Siras and Artavavaha srotas leading to Artava Atipravrutti. Abnormal uterine bleeding is a common gynaecological complaint with various aetiologies and varied pathophysiological origins. Excessive bleeding during menstruation can restrict with her daily activities, disturb her wellbeing and reducing their efficiency in society. Excessive flow of blood during menstrual and intermenstrual period creates a condition of anaemia in the patient. The Raktasthambhaka Dravya’s are not only helpful for stopping excessive and prolonged bleeding during menstruation but also regularizes menstrual cycle and acts on improving the quality of Rakta Dhatu were discussed in detail in the present paper with their clinical researches.