bluuebunny/crossref_metadata_2025 huggingface dataset:
Clinical Case of Agammaglobulinemia Late Diagnosis in Preschool Child
Authors: Kolevatova Elena S. , Shutkova Alla Yu. , Tush Elena V. , Khaletskaya Olga V.
Published: March 2022

Background. Agammaglobulinemia is a disease from the group of primary immune deficiencies with impaired antibodies production characterized by significant decrease or complete absence of B-cells. Due to the absence of pathogenetic treatment, severe bacterial lesions of various organs and tissues can develop, and they can lead to the patient death. Timely history taking and clinical and laboratory data analysis will allow to reveal this pathology early and start the therapy that can save patient's life. Clinical case description. This article demonstrates clinical case of agammaglobulinemia late diagnosis with development of severe complications and reversal of clinical manifestations in response to pathogenetic therapy. Conclusion. Despite the disease onset in the second half-year period of life, the presence of recurrent purulent processes resistant to standard treatment and the significant decrease of all immunoglobulin levels, agammaglobulinemia was suspected only at preschool age. The outcomes were disabled patient, and considerable aggravation of the quality of life.
Biotechnological potential of the forest regions of Russia and a feasibility study for integrated processing of forest biotechnological resources
Authors: Saveliev Yuriy
Published: March 2022

The article presents an overview of the state, structure and main trends in the development of the global and Russian biotechnology market in terms of assessing the prospects for using the forest biotechnological potential of Russian regions (wild berries, mushrooms, medicinal raw materials, logging industry waste). A detailed description of the structure of the world and Russian biotechnological markets is given with a justification of the market segments that are most interesting for products obtained from the processing of forest biotechnological raw materials. The author presents an overview of the most competitive and popular types of products on the market based on the processing of forest biotechnological raw materials (natural plant extracts, freeze-dried powders, essential oils, hydrolates, and others). The article contains an overview of modern technologies for the extraction of plant raw materials (including technologies for water-alcohol extraction, supercritical carbon dioxide extraction, ultrasonic extraction, hydrodynamic extraction, steam distillation, vacuum circulating extraction, and others), and also provides a feasibility study for the integrated processing of forest biotechnological resources and logging waste (green mass of coniferous woody plants), involving the choice of the most effective technologies for processing specific types of biotechnological raw materials. The review of technologies was made by the author based on the analysis of scientific articles and publications, as well as on the basis of the author's experience in the development and support of the implementation of investment projects in the field of forest biotechnologies.
Get out of the BAG! Silos in AI Ethics Education: Unsupervised Topic Modeling Analysis of Global AI Curricula
Authors: Javed Rana Tallal , Nasir Osama , Borit Melania , Vanhee Lois , Zea Elias , Gupta Shivam , Vinuesa Ricardo , Qadir Junaid
Published: March 2022

The domain of Artificial Intelligence (AI) ethics is not new, with discussions going back at least 40 years. Teaching the principles and requirements of ethical AI to students is considered an essential part of this domain, with an increasing number of technical AI courses taught at several higher-education institutions around the globe including content related to ethics. By using Latent Dirichlet Allocation (LDA), a generative probabilistic topic model, this study uncovers topics in teaching ethics in AI courses and their trends related to where the courses are taught, by whom, and at what level of cognitive complexity and specificity according to Bloom’s taxonomy. In this exploratory study based on unsupervised machine learning, we analyzed a total of 166 courses: 116 from North American universities, 11 from Asia, 36 from Europe, and 10 from other regions. Based on this analysis, we were able to synthesize a model of teaching approaches, which we call BAG (Build, Assess, and Govern), that combines specific cognitive levels, course content topics, and disciplines affiliated with the department(s) in charge of the course. We critically assess the implications of this teaching paradigm and provide suggestions about how to move away from these practices. We challenge teaching practitioners and program coordinators to reflect on their usual procedures so that they may expand their methodology beyond the confines of stereotypical thought and traditional biases regarding what disciplines should teach and how.

This article appears in the AI & Society track.
ОБ АДДИТИВНОЙ МОДИФИКАЦИИ γ-СВОЙСТВА
Authors:   Tomsk State University (Tomsk, Russian Federation), Бадмаев О.О.
Published: March 2022

The aim of this article is to modify the notion of the γ-property so that the modified property is preserved under taking a direct topological sum. To this end, we use a procedure of “saturation” of ω-covers of topological spaces. Namely, we add to each ω-cover the family of all unions of its subfamilies consisting of at most k elements (“k-saturation”), or the family of all unions of its finite subfamilies (“saturation”). Thus, we obtain for Tychonoff spaces a sequence ( k )k<ω γ′ of covering properties such that k k +1 ′ ′ γ ⇒ γ for any integer k, and 1 ′γ is the well-known γ-property. Also, the property ωγ′ such that k ω γ′ ⇒ γ′ for any integer k is obtained. It is proved that each kγ′ -property is preserved under usual topological operations, namely, taking closed subspaces, continuous images, and finite powers. It is known that the classical γ-property can be failed under passing to topological sum. Our main result means that it is impossible with respect to whole sequence ( k )k<ω γ′ . More precisely, if a space X satisfies kγ′ , Y satisfies mγ′ , then the sum X ⊕Y satisfies k +m γ′ . Nevertheless, X ⊕ X satisfies kγ′ as X itself. As another main result, we establish that the ωγ′ -property and the Lindelöf property are equivalent. It follows that any countable union of spaces Xn with the k (n) γ′ -property is a Lindelöf space.
ПРИБЛИЖЕННОЕ АНАЛИТИЧЕСКОЕ РЕШЕНИЕ ПРЯМОЙ ЗАДАЧИ ЭЛЕКТРОИМПЕДАНСНОЙ ТОМОГРАФИИ В НЕОДНОРОДНОМ КРУГЕ С УЧЕТОМ СОПРОТИВЛЕНИЯ ЭЛЕКТРОДОВ
Authors:   Tomsk State University (Tomsk, Russian Federation), Старченко А.В. , Седнев М.А. ,   National Research Tomsk State University, Панько С.В. ,   National Research Tomsk State University
Published: March 2022

An approximate analytical solution of the potential distribution in a two-dimensional circle with a radially inhomogeneous conductivity is obtained for the boundary conditions of the full electrode model, which takes into account the contact resistance of the electrodes at a given current strength. The solution is obtained by separating variables and using Fourier series, for the coefficients of which it is necessary to solve a system of linear equations. The obtained solution was compared with an approximate analytical solution of a similar problem for a homogeneous disk and with the Neumann-Robin boundary conditions. A good agreement was obtained, the quality of which improved with an increase in the number of terms taken into account in the series.
ДИНАМИКА ДВУХМАССОВОГО МИКРОМЕХАНИЧЕСКОГО ГИРОСКОПА L-L-ТИПА В РЕЖИМЕ ВЫНУЖДЕННЫХ КОЛЕБАНИЙ
Authors:   Public Joint Stock Company «Tupolev», Антонов Е.А.
Published: March 2022

This paper is devoted to a study of dynamics of an L-L-type two-mass micromechanical gyroscope (abbreviated as MMG) under forced oscillations. The mechanical-theoretical model of MMG with a sensitive element in the form of a model with two active masses (“Inertial mass -Frame”) is obtained. Based on the model, the system of differential equations is written. A distinctive feature of this paper is that an arbitrary angular velocity of the base Ω is considered. A new method is used to find a solution to the system. This method is suitable for analyzing dualfrequency systems. Finally, the solution is determined, and the amplitude-frequency characteristics of the system are described. The obtained analytical expressions and graphs are analyzed, and the reasonable conclusions about system behavior under forced oscillations are made. The proposed method for analyzing complex systems is compared with other available methods.
ОЦЕНКА ПРЕДЕЛЬНЫХ ВОЗМОЖНОСТЕЙ ВЫСТРЕЛА С ИСПОЛЬЗОВАНИЕМ ВЫСОКОПЛОТНЫХ ТОПЛИВ ДЛЯ ПОВЫШЕНИЯ ДУЛЬНОЙ СКОРОСТИ СНАРЯДА
Authors:   Tomsk State University (Tomsk, Russian Federation), Буркин В.В. , Дьячковский А.С. ,   National Research Tomsk State University, Ищенко А.Н. ,   National Research Tomsk State University, Касимов В.З. ,   National Research Tomsk State University, Рогаев К.С. ,   Tomsk State University, Сидоров А.Д. ,   Tomsk State University (Tomsk, Russian Federation), Степанов Е.Ю. ,   Tomsk State University (Tomsk, Russian Federation)
Published: March 2022

Theoretical studies aimed at demonstrating efficiency of using high-density high-energy propellants in an artillery round are carried out. Parametric studies on shot capabilities are performed using the special software package based on a mathematical model of intraballistic processes. The shot is fired using a model high-density propellant with a traveling charge placed in the bore behind the shell in addition to the main propellant charge in a medium-caliber model ballistic setup. The propellant burning law obtained by calculations and experiments on a small-caliber setup is adapted to a medium-caliber one. Charging conditions are determined to achieve the highest increase in the projectile muzzle velocity with the use of propellants as compared with a classical charging scheme of the shot at a maintained level of the required pressure. Recommendations for upgrading high-density propellants resulting in an additional increase in the projectile muzzle velocity are presented.
ТЕЧЕНИЕ ТИПА КУЭТТА С УЧЕТОМ ИДЕАЛЬНОГО СКОЛЬЖЕНИЯ НА КОНТАКТЕ С ТВЕРДОЙ ПОВЕРХНОСТЬЮ
Authors:   Institute of Engineering Science, Ural Branch of the Russian Academy of Sciences, (Ekaterinburg, Russian Federation)., Бурмашева Н.В. , Ларина Е.А. ,   Institute of Engineering Science, Ural Branch of the Russian Academy of Sciences, (Ekaterinburg, Russian Federation), Просвиряков Е.Ю. ,   Institute of Engineering Science, Ural Branch of the Russian Academy of Sciences, (Ekaterinburg, Russian Federation)
Published: March 2022

On the basis of a system of hydrodynamic equations, the unidirectional steady flow of a viscous incompressible fluid in a horizontal extended layer is studied. The solution to the governing equations is discovered in a distinguished class of functions that are linear in coordinates. The contact of the fluid with a lower hydrophobic solid boundary is described by the Navierslip condition. At the upper boundary of the layer, the temperature and pressure fields are assumed to be given, and a zero shear stress is specified. The system of boundary conditions is redefined due to the fact that all conditions for velocities are assigned as their derivatives. Zero flow rate is taken as an additional condition. The obtained exact solution to the boundary value problem is the only possible polynomial solution. The highest (eighth) degree of polynomials corresponds to a solution for background pressure. Analysis of the solution shows that it can describe a multiple stratification of kinetic-force fields. Since the analysis is carried out in a general form (without specifying physical constants that uniquely identify the fluid under study), the obtained results are applicable to viscous fluids of different nature.
Co-creation Processes Contributing to the Societal Impact of Science: Contributions from the Net4Impact Network
Authors: Girbes Sandra , Sebastián Javier , Rodríguez Xosé Pedro , Fontanals Marta , Campeny Gerard , Gómez Bruno , Soler Marta 
Published: March 2022

Meaningful citizen participation throughout the development of research projects has increased the societal impact of science. Co-creation processes promote a more significant societal impact by aligning research with societal needs. In recent years, essential advances in citizen participation in science have been identified. However, there are still critical challenges that limit citizen interaction with scientific creations. This article provides some of the contributions made by the Net4Impact network in the face of these challenges. Specifically, we analyse co-creation processes developed by those projects that have demonstrated societal impact. This qualitative study is based on the analysis of Webinars, meetings with researchers from different scientific areas and Communicative Content Analysis. As a result, this work provides six examples of societal impact in three scientific areas: social sciences, humanities, and engineering. In addition, we analyse the characteristics and implications of the different co-creation processes developed by these successful projects.
Penerimaan Cergam Pakai Masker Yuk pada Guru Taman Kanak-Kanak di Kecamatan Blimbing Kota Malang
Authors: Ekawati Rany
Published: March 2022

COVID-19 (coronavirus disease 2019) adalah penyakit yang disebabkan oleh jenis coronavirus baru yaitu Sars-CoV-2 dengan menunjukkan gejala gangguan pernafasan akut seperti demam diatas 38 derajat celcius, batuk dan sesak nafas bagi manusia. Metode pelaksanaan dalam penelitian ini dibagi menjadi empat bagian yaitu persiapan, pelaksanaan, monitoring dan evaluasi, pembuatan laporan. Jumlah kasus Positif covid-19 di Kecamatan Blimbing terbanyak dari pada kecamatan lain di Kota Malang sehingga anak-anak berisiko terkena Covid-19. Metode pelaksanaan dalam penelitian ini adalah deskriptif. Penelitian ini mengedukasi anak sekolah TK di Kecamatan Blimbing dengan cerita bergambar Pakai Masker Yuk agar mau menggunakan masker di masa pandemi COVID-19. Media edukasi cergam mendapaTKan respon dari guru yaitu isi cerita baik sebanyak 71 persen, kalimat yang digunakan baik sebanyak 61,3 persen, suara dalam video baik sebanyak 54,8 persen. Kesimpulan dalam penelitian ini yaitu sekolah TK yang berada di Kecamatan Blimbing dengan jumlah 31 TK mendapatkan edukasi dengan story telling Cerita Bergambar (cergam) Pakai Masker Yuk, dan dilengkapi dengan video edukasi yang menarik sehingga mendapatkan respon yang baik dari murid beserta guru.
Gambaran Aktivitas Sedenter, Tingkat Stress, dan Tingkat Depresi pada Siswi Sekolah Menengah Atas Negeri 4 Malang
Authors: Hapsari Anindya , Tama Tika Dwi , Andiana Olivia
Published: March 2022

Masa remaja merupakan masa peralihan dari anak-anak menjadi dewasa dimana pada masa ini terjadi perubahan fisik, psikologis, dan sosial, yang berpotensi menimbulkan masalah atau gangguan jangka panjang jika tidak ditangani secara tepat. Diantara masalah yang dapat dihadapi remaja adalah kurangnya aktivitas fisik, yang mengacu pada peningkatan aktivitas sedenter, yang telah diketahui berhubungan erat dengan peningkatan prevalensi penyakit tidak menular (PTM) sejak usia muda. Selain itu, permasalahan kesehatan remaja yang lain dari dimensi kesehatan jiwa adalah peningkatan prevalensi depresi, terutama pada remaja putri. Depresi ini dapat disebabkan karena ketidakmampuan remaja memanajemen stress dan memilih mekanisme koping stress yang salah. Penelitian ini bertujuan mengetahui gambaran aktivitas sedenter, stress, dan depresi pada siswi Sekolah Menengah Umum di Kota Malang. Jenis penelitian adalah deskriptif menggunakan rancangan potong lintang dengan pendekatan kuantitatif. Populasi penelitian adalah siswi kelas X SMUN 4 Malang dengan teknik total sampling sehingga didapatkan 116 responden. Instrumen yang digunakan adalah kuesioner yang telah tervalidasi. Hasil penelitian menunjukkan bahwa sebagian besar responden memiliki aktivitas sedenter tinggi (85,34 persen), tingkat stress sedang (76,72 persen), dan tingkat depresi minimal (81,89 persen). Kesimpulan dari penelitian ini adalah sebagian besar siswi kelas X SMUN 4 Malang memiliki aktivitas sedenter yang tinggi, tingkat stress sedang, dan tingkat depresi minimal. Untuk meningkatkan derajat kesehatan masyarakat utamanya remaja di SMUN 4 Malang, disarankan kepada pihak terkait untuk menyusun kebijakan tentang kewajiban aktivitas fisik di lingkungan institusi pendidikan serta meningkatkan peran bimbingan dan konseling remaja baik di institusi pendidikan maupun di institusi kesehatan.
Edukasi Upaya Pencegahan dan Deteksi Dini Kanker Serviks berbasis Media Video Animasi dan Flipcharts untuk Pelajar Kota Malang
Authors: R Windi Chusniah , Ratih Suci Puspita , Ekawati Rany
Published: March 2022

Kanker pada umumnya adalah sel yang membelah secara tidak terkendali. kanker serviks yang disebabkan oleh HPV atau Human Papilloma Virus. Setiap 2 menit di dunia, seorang wanita meninggal karena kanker serviks, sedangkan di Indonesia setiap 1 jam. Semua wanita berisiko terkena kanker serviks, termasuk remaja dimana remaja putri akan menikah dan melahirkan, sehingga meningkatkan risiko kanker serviks. Pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pengetahuan mahasiswa tentang upaya pencegahan dan deteksi dini kanker serviks melalui media promosi kesehatan. Pengabdian kepada masyarakat dilakukan secara acak kepada 20 mahasiswi yang bersedia menjadi responden. Pengabdian kepada masyarakat melalui media promosi animasi video kesehatan dan flipchart kalender dapat meningkatkan pengetahuan mahasiswa tentang upaya pencegahan dan deteksi dini kanker serviks.
Korelasi Status Perkawinan, Pendapatan Keluarga, Kebiasaan Makan “Muluk” dan Konsumsi Gorengan terhadap Risiko Diabetes pada Wanita Lansia Awal (46-55 Tahun)
Authors: Sari Dhian Kartika , Wardani Iing Merillarosa Kharisma , Masyiyah Shofiyatul , Samah Dea Aflah , Alma Lucky Radita , Katmawanti Septa , Ulfah Nurnaningsih Herya
Published: March 2022

Tujuan penelitian ini adalah untuk menganalisis hubungan status perkawinan, pendapatan keluarga, kebiasan makan “muluk”, dan konsumsi gorengan terhadap risiko diabetes pada wanita lansia awal berusia 46 sampai 55 tahun. Metode yang digunakan adalah penelitian observasional dengan responden sebanyak 83 orang. Instrumen penelitian yang digunakan adalah kuisioner. Dari hasil penelitian ini diketahui bahwa sebanyak 89,2 persen responden memiliki status perkawinan menikah. Diketahui juga bahwa rata-rata pendapatan keluarga dari responden adalah dibawah Upah Minimum Regional (UMR) (62,7 persen). Mayoritas responden menyampaikan bahwa mereka pernah makan muluk seminggu sebanyak 7 kali (27,7 persen) dan 75,9 persen responden menyampaikan bahwa lebih nyaman menggunakan muluk saat makan. Selain itu, sebanyak 33,7 persen mengakui menjadikan gorengan sebagai camilan yang biasa dikonsumsi. Adapun risiko diabetes diketahui bahwa 86,7 persen berada pada kategori risiko rendah. Hasil uji bivariat chi-square menunjukkan bahwa tidak ada hubungan antara status perkawinan (p value: 1,00), pendapatan keluarga (p value: 1,00), metode makan yang lebih nyaman diterapkan (p value: 1,00), dan konsumsi gorengan (p value: 0,319) dengan risiko diabetes. Hasil uji bivariat Kenndals Tau menunjukkan bahwa tidak ada hubungan antara frekuensi makan muluk (p-value: 0,897) dan jumlah jari yang digunakan untuk muluk (p value: 0,596) dengan risiko diabetes.
Artificial Neural Network based MPPT Algorithm with Boost Converter topology for Stand-Alone PV System
Authors: YILMAZ Mehmet , CORAPSİZ Muhammedfatih
Published: March 2022

The increasing energy need in parallel with the technology development and the depletion of the resources have increased the importance of alternative energy resources. Solar energy systems are frequently preferred due to their advantages such as not having moving parts, being reliable and working without noise. Production of electricity from solar energy is obtained by serial or parallel connection of photovoltaic (PV) panels, depending on the desired voltage and current values. DC-DC converters are used to convert the energy obtained from the PV panels to the desired grid values. Maximum power point tracking (MPPT) algorithms are used in order to obtain the highest possible efficiency from the PV panels. MPPT algorithms control the duty period (D) ratio of DC-DC converters and obtain maximum energy. In this study, an Artificial Neural Network (ANN) based MPPT algorithm is proposed. Firstly, the temperature and irradiance data at the PV panel input are trained using the Levenberg-Marquardt algorithm. As a result, a reference voltage is generated and MPPT is realized by comparing it with the voltage produced by the PV panel. In order to evaluate the performance of the proposed algorithm, it is compared with the traditional MPPT methods such as Perturb & Observe (P&O) and Incremental Conductance (INC). As a result of the simulation studies, it has been observed that ANN based MPPT is more successful than P&O and INC algorithms for several irradiance and temperature conditions.
Echocardiographic Evaluation of Cardiac Involvement in Patients with COVID-19
Authors: COŞGUN Muharrem Said
Published: March 2022

Cardiac involvement in coronavirus disease 2019 (COVID-19) is closely associated with morbidity and mortality. Patients with preexisting cardiovascular disease and/or cardiovascular involvement have poor prognoses. This prospective study aimed to identify patients requiring cardiac function evaluation using echocardiography. Data from 243 patients with a confirmed COVID-19 diagnosis between June and November 2021 were analyzed. The demographic and clinical characteristics of all participants were recorded, and echocardiographic examinations were performed. The patients were divided into two groups according to the presence or absence of abnormalities on echocardiography. Echocardiographic findings were normal in 133 (54.7%) patients and abnormal in 110 (45.3%) patients. Abnormal findings were significantly more common than normal findings in patients requiring intensive care and patients with elevated cardiac biomarker (troponin I and/or brain natriuretic peptide) levels (p < 0.001, in both). Conversely, normal findings were significantly more common than abnormal findings in patients requiring isolated wards and the indication of suspected left and/or right ventricular failure (p < 0.001, in both). The results suggest that high cardiac biomarkers and requiring intensive care may facilitate the selection of patients who can benefit from echocardiographic imaging, which is important given the increased risk of viral transmission when performing echocardiography.
Quantum Codes from (1-2w-2uv)-Constacyclic Codes over the F_q+uF_q+vF_q+wF_q+uvF_q
Authors: TETİK Ceremnur , DERTLİ Abdullah
Published: March 2022

In this paper, we give construction of quantum codes over F_q from (1-2w-2uv) - constacyclic codes over the F_q+uF_q+vF_q+wF_q+uvF_q, where u^2=u,v^2=v,w^2=w,uv=vu,uw=wu=vw=wv=0, q=p^m and p is an odd prime. We determine the parameters of quantum error correcting codes which constructed from (1-2w-2uv) - constacyclic codes over the F_q+uF_q+vF_q+wF_q+uvF_q.
Energy, Exergy and Sustainability Indicators of Photovoltaic Panel Cooling under Forced Convection
Authors: BAYRAK Fatih
Published: March 2022

Photovoltaic (PV) panels generate some of their energy as waste heat while converting solar radiation into electricity. This heat in photovoltaic panels adversely affects the output parameters of the panels. For this reason, there are many studies on cooling of PV panels in the literature. In this experimental study, waste heat was removed by placing DC fans with different numbers and different consumption power on 80 W monocrystalline panels. According to the results obtained from the experiments, while the net power of the reference panel was 62.42W, the net power of the E4 system (with 4 fans and the consumption power of the fans was 10W) was measured as 64.1W. The highest exergy efficiency and sustainability index values among all systems were also obtained from the E4 system.
A Review on Welding Techniques of Metallic Foams
Authors: KARABULUT Gizem , BEKÖZ ÜLLEN Nuray
Published: March 2022

Metallic foams are a new type of material class using in the much-diversified area such as automotive, biomedical, and construction etc. Thanks to its porous structure, it stands out with its energy and impact absorption as well as its lightness. Due to the properties, metal foams have the potential for use in many applications. As the number of uses and potential applications increases, it becomes important to develop adequate joining technologies for metallic foams and to select appropriate methods for their widespread industrial use. However, various problems are encountered in welding metallic foams with a foam or a face sheet. The most important feature that causes differences in the welding process and characteristics of these materials is porosity. While the methods such as MIG/TIG could be preferred in the past, the methods such as laser welding have come to the fore with today's needs. The welding of metallic foams is a subject that is still being studied and developed. In this study, studies in the literature are examined to understand the problems encountered in metallic foams during welding and to develop welding techniques. It is aimed to create a wide source for the welding of metallic foams by referring to the methods used and the advantages and disadvantages of the methods with this review.
Autosuficiencia de lácteos en Iztapalapa: el caso del rancho San Cristóbal en Nextipac (1955-1975)
Authors: Lara Manríquez Fernanda Isabel
Published: March 2022

En el presente trabajo se aborda la importancia que tuvieron los ranchos y establos al oriente de la ciudad de México, en Iztapalapa, para la autosuficiencia de lácteos, particularmente el rancho San Cristóbal en San Juanico Nextipac, durante el periodo de 1955 a 1975. Se trata de un momento de relevancia en el acontecer de la ciudad de México y que ha sido muy poco explorado desde las humanidades, principalmente desde la historia. Por ello es que en este artículo se da prioridad a los testimonios orales frente a otras fuentes, haciendo uso especial de la metodología de la historia oral. Además, se abordan las transformaciones espaciales por las que pasaron los establos y ranchos a mediados de la década de los setenta del siglo pasado, como consecuencia de las medidas que tomaron los actores gubernamentales, quienes en su momento lo consideraron necesario para resolver ciertos fenómenos sociales que ocasionaba la urbanización.
Numerical Study on the Deformation Behavior of Geosynthetic-Encased Stone Columns Supporting Embankments
Authors: KAHYAOĞLU Mehmet Rifat , DOĞAN Tuncay
Published: March 2022

The method of encasing the stone column with a proper type of geosynthetic material is a widely used technique to provide the required lateral confinement and to avoid the dispersion of granular column material into soft clay. Along with the improved ultimate load capacity and the reduced settlement and bulging, the geosynthetic encasement preserves the easy drainage ability of stone columns. This paper presents the finite element analysis results of a hypothetical embankment on a soft soil deposit which is improved by geotextile encased stone columns and geogrid reinforced sand mat on top. At first, numerical results of three dimensional (3D) finite element model (FEM) were validated via the experimental data of previous field studies. Afterward, parametric studies were carried out on the FEM considering the effect of the sand mat thickness, the stiffness of the geosynthetic reinforcement, and the geosynthetic encasing length and encasement stiffness on both the horizontal and vertical deformation of stone columns. Settlement differences between columns and soft soil in both the short term and long term were also determined. The optimum values of sand mat layer thickness, vertical encasement length, and geosynthetic stiffness are recommended to be used for preliminary designs.
The Efficiency, Benefits and Profitability of Lohn Production in RN Macedonia for a German Textile Company
Authors: Mitreva Elizabeta , Janeva Aneta
Published: March 2022

This paper shows the efficiency and profitability of the textile lohn production in the Republic of North Macedonia as well as in other countries in the Western Balkans, the so-called third countries. This geographical region is attractive because of the cheap labor, as well as the profitability that arises as a result of the economic system of work. The paper makes comparison with the production in Western European countries, where the wage for the labor is several times higher, and at the same time the taxes are also higher. In the global market, the third textile production option is the Far East, or for the most part China, as a favorable option, but with very long delivery times due to the physical distance from the European continent and the transport time for the final products. In this paper we will show the results and analyses through an example of a German textile company oriented towards production of fashion textile products in RN Macedonia, including efficiency of the textile production in the Western Balkans, as the most acceptable option for lohn production. The solutions were based on the concept of improving the efficiency of operations, especially in the area of organization of production operations, in a way that enabled complete elimination of errors, greater productivity and increased quality of the final product, within a precisely defined time frame.
Constructing a Pedagogy of Apparentness
Authors: Tramantano Adam
Published: March 2022

In this explorative essay, I discuss the complexity of apparentness as it pertains to being a teacher educator and an artist. Notions from creative and postmodern research approaches help me suggest that it is a quality of perception and not a quality of art or any other kind of text. In this exploration of how apparentness comes in and out of focus for me as an educator and as an artist, I begin with a discussion of the role of art in my becoming a teacher educator; I realize art’s efficacy as a site for exploring the acts of facilitating discussions, drawing the attention of others, and raising an awareness for what we believe matters. As a painter, I reflect on and inquire into what is laudable and limited in these forays of connecting art to teaching and education. The research approach is narrative and reflective, not intent on the discovery of discreet findings, but more interested in discovering questions and in offering some ways of framing my experiences and their possible implications for educators, teacher education, art, and artists. I ponder the parallels between art and education, particularly in how viewing art can be a metaphor for classroom discussions. The essay is concerned with what we believe is apparent and mysterious, and how we engage in dialogue with the resonance and dissonance of the perceptions of others.
Nomadic Ethics
Authors: Carter Stephen P.
Published: March 2022

In response to Maureen Flint’s (2020) performance and essay, Fingerprints and Pulp, on the ethics of truncating and flattening research participants in qualitative research, I extend this ethical concern to the voices of scholars flattened in qualitative research and writing processes. Scholars cite for many reasons, but what is there that holds us to account for our treatments of academics that come before; how can we avoid flattening and abusing those we cite? Through endeavouring to recognise and protect ghosts and nomadic identities of those other than the author in the research and writing process, I propose a new way of re-animating and re-embodying the haunting, nomadic voices in cited texts, in order to minimise further, future truncations and limitations of the other in academic writing. Attending to the ghosts allows for more ethical and just behaviour towards those cited. Seeing the multitude of ghosts haunting scholarly work obliges more ethical behaviour toward those voices flattened in writing.
On Space, On Place
Authors: Phan Anh Ngoc Quynh
Published: March 2022

Using poetic self-study, the author recounted her own lived experiences during the first year as an international doctoral student in New Zealand to explore how her academic identity emerged and (re)constructed. The article draws on theories of space and place, investigating the spatial production and social interactions of the author within spaces that, in turn, influenced her sense of being an academic. While literature has been more concerned with the questions of what activities, relations, and contexts contribute to the academic identity development of doctoral students, the author seeks to forefront the where of academic identity configuration.
Non-equilibrium cooling and heating of an MBBA liquid crystal at the first-order phase transition in a long cell
Authors: Kazakevich Vladimir S. , Klyukach Igor L. , Mordovin Gennady A.
Published: March 2022

The first-order phase transition of an MBBA nematic liquid crystal with benzene impurity has been studied by the critical opalescence method at a large cell thickness. Opalescence has been observed at two critical transition points. The spatial transverse parameters of the domains are determined from the Fraunhofer diffraction. The hypothesis about the longitudinal correlation parameter of domains is equal to the cell length has been proposed.
CEDNIK Syndrome, a Rare Neuro-Cutaneous Disorder in an Iranian Patient: Case Report and Review of Specific Neuro-Ichthyotic Syndromes
Authors: Ashrafzadeh Farah , Esmaeilzadeh Mahla , Mohammadi Asl Javad , Hashemi Narges , Imannezhad Shima , Saeedi Zand Nazanin , Sadat Mirzadeh Hanieh
Published: March 2022

Cerebral dysgenesis, neuropathy, ichthyosis, and keratoderma (CEDNIK) syndrome is an autosomal recessive neuro-cutaneous disorder characterized by a collection of clinical manifestations, including microcephaly, cerebral dysgenesis, palmoplantar keratoderma, facial dysmorphism, and ichthyosis. The etiology of this condition has been proved to be a homozygous mutation in the SNAP29 gene, which has an essential role in dermatological and neurological manifestations of this syndrome. In this report, we present the first documented Iranian patient with CEDNIK syndrome. So far, only 14 cases of this condition have been reported globally.
Naegleria fowleri from Pakistan Has Type-2 Genotype
Authors: Aurongzeb Muhammad , Rashid Yasmeen , Ahmed Naqvi Syed Habib , Khatoon Ambrina , Abdul Haq Sadia , Azim Muhammad Kamran , Kaleem Imdad , Bashir Shahid
Published: March 2022

Background: Primary amoebic meningoencephalitis (PAM) is an acute and fulminant CNS infection caused by Naegleria fowleri. Recreational activities and ritual ablution with contaminated warm fresh water are the main reason of PAM. Pakistan ranked the second most affected country, where most of the PAM incidences were reported from Karachi, Pakistan.
Methods: In May, 2019, a 28-yr-old suspected PAM patient came to the Imam Zain-Ul-Abdin Hospital, Karachi. Biochemical and cytological investigations of patient`s CSF were carried out at Karachi Diagnostic Center and Molecular Biology Lab. Sequencing of Naegleria sp. specific (ITS) primer-based amplicons was performed from both patient`s CSF and water samples followed by multiple sequence alignment and phylogenetic studies.
Results: Biochemical and cytological investigations of patient`s CSF showed 5 mg/dl glucose, 240 mg/dl total protein and 2260/mm3 TLC suggesting acute meningoencephalitis. PCR-based analyses of patient`s CSF and his residential tap water samples using Naegleria sp. specific (ITS) and N. fowleri specific primers revealed the presence of N. fowleri DNA. Nucleotide sequences of ITS primer-based amplicons from both patient`s CSF and water samples were submitted in GenBank under the accession numbers MT726981.1 and MT726226.1, respectively. According to phylogenetic analysis, N. fowleri isolate from Pakistan has shown the least node age of seven.
Conclusion: Here, for the very first time in Pakistan, N. fowleri genotype has been identified as type-2. Phylogenetic analysis showed that N. fowleri isolate from Pakistan is among the latest descendants, i.e., evolved later in life.
Treatment of Murine Toxoplasmosis with Oral and Parenteral Artemether and Following by Detection of B1 Gene by Quantita-tive Real-Time PCR (qPCR) for Evaluating Parasite Density
Authors: Mikaeiloo Hajar , Ghaffarifar Fatemeh , Dalimi Abdolhossein , Zuhair Hassan Mohammad , Sharifi Zohreh
Published: March 2022

Background: Toxoplasma gondii is an obligate intracellular parasite that can infect humans and animals. As the choice drug have shown side effects, development a new drug with low toxicity will be necessary.
Methods: BALB/c mice were infected with tachyzoiets of T. gondii. After treatment by oral and parenteral artemether (250 µg/mice) and sulfadiazine (50 µg/mice), we evaluated the rates of survival in treated and control mice. The fold change of B1 gene (target gene) expression in liver and brain of mice treated with parenteral artemether (i.p.), oral artemether (via gavage) and sulfadiazine, were detected by using the Real-Time quantitative PCR.
Results: Both treatment with sulfadiazine and artemether showed significant prolongation in time to death of the infected mice compared to the control group. Median survival days for parenteral artemether, oral artemether, sulfadiazine and control group were 8, 11, 12 and 6 d respectively. Expression of B1 gene in liver and brain of mice after treatment with artemether and sulfadiazine were reduced in comparison to housekeeping gene (β-tubulin gene). The fold change (comparing to control group) for parenteral artemether, oral artemether, sulfadiazine is 0.034, 0.027 and 0.111 for liver and 0.220, 0.425 and 0.366 for brain respectively.
Conclusion: Artemether is effective to control the tachyzoites of T. godii in vivo conditions and oral treatment is more effective than parenteral treatment. Due to its low cytotoxicity and its high effective action against the tachyzoietes of T. godii in susceptible animals.
Clinicopathological Review of Human Coenurosis in Kwazulu-Natal, South Africa: A Retrospective Single Center Study
Authors: Bonginkosi Nhlonzi Gamalenkosi , Mwazha Absalom
Published: March 2022

Background: To describe the clinicopathological features of human coenurosis diagnosed at a single center in an academic Anatomical Pathology Laboratory, KwaZulu-Natal, South Africa.
Methods: This was a 10-year retrospective laboratory based study, from 2011-2020, which reappraised the clinical presentation, histomorphological tissue reaction patterns and outcomes in patients diagnosed with coenurosis.
Results: Five cases of coenurosis and 19 cases of cysticercosis were diagnosed during the study period. Following re-appraisal of the slides, 6 cases of coenurosis were confirmed and included in the study cohort. The anatomical distribution of disease was as follows: brain (1), liver (1), eye (1) and soft tissue (3). There were 3 males and 3 females and the patients’ age ranged from 2 to 46 (mean 22.2) yr. Three patients were HIV positive whilst the clinical history of the infection was not available for the other 3 patients. All patients presented with mass effect related symptoms, ranging from headache to a painful soft tissue swelling. Two cases displayed synovial metaplasia in addition to characteristic chronic subacute inflammation and fibrosis. One case had supportive inflammation. Two cases comprised of coenuri exclusively and therefore it was not possible to assess tissue reaction.
Conclusion: We describe the first cases of human coenurosis in HIV positive patients and for the first time report synovial metaplasia as one of the reaction patterns of coenurosis. Whenever cysticercosis and hydatidosis are considered clinically, a negative serology should prompt clinicians to consider coenurosis in addition to the neoplastic diagnostic considerations.
Assessment of the Endoparasite Fauna amongst the Rodents in Kurdistan Province, West of Iran
Authors: Mohammadi Ali , Bozorgomid Arezoo , Sedaghat Mohammad Mehdi , Mowlavi GholamReza , Abai Mohammad Reza , Mostafavi Ehsan
Published: March 2022

Background: We aimed to evaluate the rate of infection by endoparasites amongst rodents in the western regions of Iran to enhance the level of knowledge amongst health authorities in this entity.
Methods: This study was conducted in the west and southwest of Kurdistan Province, including the cities of Sanandaj, Marivan, and Sarvabad. The field mission of this work was performed in three seasons’ spring, summer, and autumn. The rodents were captured alive and their gastrointestinal tracts were evaluated for the worm endoparasites.
Results: Herein, 208 rodents from 15 types of seven species, including Apodemus, Meriones, Mus, Sciurus, Cricetulus, Microtus, and Dryomys, were captured. In addition, 67 (32.21%) rodents were infected with endoparasites and 10 types of worms endoparasites, including Syphacia muris, Streptophagus spp., Mastophorus muris, Skrjabinema spp., Trichostrongylus spp., Trichuris muris, Hymenolepis nana, Hymenolepis dimimuta, Heligmosomoide spp., and other oxiuros were isolated from their gastrointestinal tracts. Most of these parasites (60%) were isolated from their small intestine whereas they were least (10%) found in their stomach and cecum.
Conclusion: Having compared the results of this study with other studies in different regions of Iran, there is a higher variety of rodents and worm parasites in these regions of Iran.
Inhibitory Effect of Hemiscorpius lepturus Scorpion Venom Frac-tions on Tachyzoites of Toxoplasma gondii
Authors: Rostamkolaie Lida Khaleghi , Hamidinejat Hossein , Razi Jalali Mohammad Hossein , Najafzadeh Varzi Hossein , Seifi Abadshapouri Massoud Reza , Jafari Hedieh
Published: March 2022

Background: The present study determined the effect of the fractions obtained from Hemiscorpius lepturus scorpion venom on the tachyzoite of Toxoplasma gondii.
Methods: The fractions of dried venom of He. lepturus scorpion of Khuzestan Province, southern Iran in 2019 were isolated through gel filtration chromatography, and then tachyzoites were exposed to fractions of venom at different concentrations. Trypan blue counting and MTT were applied to assay tachyzoite viability, and the inhibition of the cellular growth of fractions in Vero cells was evaluated.
Results: The maximum effect on tachyzoite was observed in fraction 5 of venom. To further separate the protein, fraction 5 was used in high-performance liquid chromatography assay to purify its proteins. Based on the results of HPLC of fraction 5, among which the second peak, a peptide with <10 KDa representing a more potent effect in eliminating the tachyzoite of T. gondii.
Conclusion: The scorpion venom-purified fractions possess anti-parasitic activity against the tachyzoite of T. gondii and can be used in parasite-controlling studies.
The Effect of Preoperative Albendazole Treatment on Intramus-cular Cyst Structure in a Patient with Simultaneous Cystic Echinococcusis of Liver and Vastus Lateralis Muscle
Authors: Ozsahin Mahmut Kursat , Karaismailoglu Bedri , Davulcu Cumhur Deniz , Sahin Erdem , Hız Murat
Published: March 2022

We report a 44-years-old woman with cystic echinococcosis (CE) who presented with simultaneous involvement of liver and vastus lateralis muscle to Istanbul University-Cerrahpasa, Istanbul, Turkey in 2020. Although she underwent surgery for the liver, the intramuscular mass was ignored. While the patient was under post-operative albendazole treatment, she was investigated for the mass on her right thigh which was excised later. The comparison of magnetic resonance imaging before and after albendazole treatment showed that albendazole eliminated the intramuscular vesicle structures by accelerating the degeneration process of the cyst. The comparison of pathology samples sent from both liver and intramuscular CE also revealed that the albendazole has left the laminar membrane intact, degenerate the germinative membrane, thereby reducing the intra-vesicle pressure and also caused the scolex structures to disappear. To the best of our knowledge, this is the first paper to report the effect of preoperative albendazole treatment on the structure of intramuscular CE.
Abortion Related to Toxoplasma gondii Infection in a Bactrian Camel (Camelus bactrianus) in Greece: A Case Report
Authors: Komnenou Anastasia Th. , Giadinis Nektarios D. , Kritsepi-Konstantinou Maria , Thomas Angelos-Lauris , Danika Stefania , Terpsidis Konstantinos , Petridou Evanthia , Papadopoulos Elias
Published: March 2022

A female, 5 yr old Bactrian camel was presented to the Exotic and Wildlife Medicine Unit, School of Veterinary Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece, with severe dehydration, depression, anorexia, mild dyspnea and diarrhea. Supportive treatment immediately initiated with fluids, electrolytes and broad-spectrum antibiotics. The general condition of the animal was stable for the next 3 days, but at 4th day became worse, since the camel remained in sternal recumbency, denied to drink water and abortion of a mummified fetus was noticed. The aborted fetus and fetal membranes were submitted for laboratory examinations (bacterial cultures, MZN, cytology, PCR) that revealed Toxoplasma gondii infection. Treatment with sulfadimidine improved the situation of the animal that returned to its farm 1 week later. This seems to be the first reported case in the literature of confirmed toxoplasmic abortion in camels.
The effect of endometrial injury on pregnancy rate in frozen-thawed embryo transfer: A randomized control trial
Authors: Aflatoonian Abbas , Baradaran Bagheri Ramesh , Hosseinisadat Robabe
Published: March 2022

Implantation failure is one of the most important factors limiting success in IVF treatment (1). Embryo implantation is a critical process of embryonic attachment to endometrium and subsequent invasion into uterine wall (2). Uterus is receptive during mid-secretory phase (days 19-23) of menstrual cycle, which is known as window of implantation (2). Implantation of embryo is a multiple process including several cytokines and growth factors, along with a dialogue between embryo and uterine endometrium (3). Numerous factors have been contributed increasing embryo implantation success (4). Majority of trials have demonstrated favorable effect of endometrial injury on implantation success rate, especially in women with recurrent implantation failure (RIF), while some studies failed to detect any benefit (5-13).
Kalma et al suggested that “local injury to endometrium causes significant changes in pattern of expression of genes related to implantation” (14). Gnainsky et al reported that “endometrial injury induces an inflammatory reaction which favors implantation” (15). Dendritic cells, natural killer cells and macrophages are employed to local injury and increased amounts of cytokines, chemokines and growth factors are secreted, thus resulting in successful implantation (15, 16).
To our knowledge, there has not been enough research due to the effectiveness of endometrial injury prior to frozen-thawed embryo transfer (FET) cycle. The purpose of our trial was to explore whether endometrial injury in luteal phase prior to FET cycle would improve pregnancy outcomes?