bluuebunny/crossref_metadata_2025 huggingface dataset:
Evidence based medicine and pharmacy curriculum: an insight into Indian perspective
Authors: Chandran Viji Pulikkel , Khan Sohil , Kulyadi Girish Pai , Devi Elsa Sanatombi , Thunga Girish
Published: April 2020

World Health Organization recommends doctor population ratio as 1: 1000 and in India the ratio is 0.62: 1000. With the ever growing population and tremendous patient pool in India the significant challenge faced by clinicians is lack of skilled allied health professionals who can assist in providing timely, unbiased, critically appraised health information. Pharmacists are the most accessible health professionals and thereby crucial in facilitating rational medication usage and working closely with the public and multidisciplinary health care team. The goal of patient care can be achieved through the focused skill development programs embedded in health students’ curriculum. Indian pharmacy curriculum should be fostered with inclusion of evidence based medicine focused training programs, workshops, case studies, digital stories, e - pocket cards and simulations. This article represents current status of evidence based medicine learning and teaching in Indian pharmacy curriculum.

Bangladesh Journal of Medical Science Vol.19(4) 2020 p.603-608
The Visual and Refractive Status in One Sample Population of ‘Orang Asli’(Indigenous) Children in Hulu Langat, Selangor
Authors: MN Fairuz , MF Noor Farasuhana , AI Mohd Zaki , S Noorsuhaila
Published: April 2020

Background: The aim of this study is to assess the visual and refractive status among ‘Orang Asli’ (indigenous) children in Kampung Sungai Lalang, Semenyih, Selangor. Uncorrected refractive error is a major burden among children around the world. It results in a significant number of problems among this high-risk group including educational loss, low productivity and impaired quality of life. Besides that, there are lacking information regarding vision problems among aborigine children or ‘Orang Asli’ in Malaysia. This study was undertaken to determine the prevalence of refractive error, and the association of the refractive error and visual acuity with age among ‘Orang Asli’ children.

Methods: A cross sectional study was conducted on ‘Orang Asli’ children (n=43) where 51.2% were male and 48.8% were female. Visual acuity and refraction assessment were done on every child using Refractive Error Study in School Children (RESC) protocol.

Results: The prevalence of refractive error was simple myopia (1.2%), simple hyperopia (18.6%), compound myopic astigmatism (7.0%), and mixed astigmatism (73.3%) respectively. The visual acuity measurement shows that the majority of subjects achieved 6/6 represented by 88.4% of the right eye and 86% of the left eye. There is no association between refractive error and age (P>0.05).

Conclusion: This study concludes that there is a high prevalence of hyperopia among ‘Orang Asli’ children and There is no association of refractive error with age and gender. Therefore, there is a need to create better awareness programs among the parents about the importance of eye examination to their children.

Bangladesh Journal of Medical Science Vol.19(4) 2020 p.609-613
Coping strategies and education of parents of autistic children in Bangladesh
Authors: Begum Fardaus Ara , Islam Md Shafiqul , Rahman Abu SMMH
Published: April 2020

Objectives: Bangladesh is a country characterized by the shared cultures of different ethnic groups. Parents in different cultures demonstrate diverse psychological functioning when caring for a child with a chronic disability such as autistic disorder. Few investigations have been conducted in Bangladesh regarding the coping strategies used by parents of autistic children. Therefore, the purpose of this study was to examine the coping strategies of parents raising autistic children in Dhaka city. We also studied the relation between the coping strategies of parents with autistic children and the parents’ educational status.

Materials and Methods: A total of 44 parents with autistic children participated in this survey and were randomly selected from a simple sample comprising parents of children attending special schools in Dhaka city, Bangladesh. Data were collected through questionnaires on coping strategies and were administered by an interviewer. A chi square test was conducted to determine the significance of the relation between education and different coping strategies.

Results and Discussion: Eight groups of coping strategies were selected as follows: Confrontive coping, Distancing from problem, Seeking social support, Self-controlling, Accepting responsibility, Planful problem-solving, Escape-avoidance, and Positive reappraisal. A total of 34, 10, 26, 19, 17, 32, 6, and 35 parents chose “at least try,” “not overanalyzing,” “get professional help,” “separate own feelings,” “conduct self-evaluation” “apply more effort….;” “hand over…,” “fantasies for turn the….,” “wish for over the…,” and “change daily lifestyle”, respectively. Moreover, a significant relation was revealed between parents’ education and the strategy, “accepting responsibilities.”

Conclusion: We concluded that parents of autistic children need more social support, counseling, and higher education to support their child’s special needs, as well as ensure their own physical and mental wellbeing.

Bangladesh Journal of Medical Science Vol.19(4) 2020 p.614-619
Examination of the effect of the gender factor on university students’ physical activity level
Authors: Dikmen Yurdanur , Akduran Funda , Keser Nurgül , Cinar Nursan
Published: April 2020

Objective: Scientific research provide information concerning an insufficient level of physical activity of young people. This study was conducted to determine the levels of physical activity among university students.

Materials and Methods: In 2014-2015 academic year, 510 students voluntarily participated in this study. To obtain data, the Personal Information Form and to determine the levels of physical activity. International Physical Activity Questionnaire (IPAQ) were used.

Results and Discussion: It is found that the 32.8% of students were not physically active, 49.2% of them had low physical activity level, 18% of students had adequate physical activity level to protect their health. Although it was found that the male students’ physical activity scores, moderately intense activity scores, intense activity scores and walking activity scores significantly higher than girls’ activity scores (p<0.05), there is no significant difference between sitting activity scores (p<0.05). Between students who have Body Mass Index over and under 25 kg/m2, there was no significant difference found between total physical activity, moderately intense activity, intense activity, walking activity and sitting time scores (p<0.05).

Conclusion: It was determined that university students have low levels of physical activity and male students have higher physical activity levels than female students.

Bangladesh Journal of Medical Science Vol.19(4) 2020 p.625-631
Repositorios digitales y redes sociales académicas: ¿una coexistencia necesaria?
Authors: Gómez-Castaño Javier
Published: April 2020

En este texto reflexionamos sobre las razones que impulsan a los investigadores a difundir sus publicaciones científicas en las redes sociales académicas, así como sus reticencias a la hora de autoarchivar dichas publicaciones en los repositorios institucionales. Se describen algunas de las acciones llevadas a cabo en RUA, Repositorio Institucional de la Universidad de Alicante, para asegurar el depósito y mejorar la visibilidad de la producción de nuestros investigadores.
Kesiapsiagaan Masyarakat Lempuing Menghadapi Bencana Gempa Bumi
Authors: Utama Tuti Anggriani , Delfina Rina , Saleha Nurmukaromatis
Published: April 2020

Kesiapsiagaan bencana adalah serangkaian kegiatan yang dilakukan  untuk  mengantisipasi  bencana  melalui pengorganisasian serta melalui langkah yang tepat guna dan berdaya guna. Provinsi Bengkulu merupakan salah satu wilayah yang rawan terhadap bencana gempa bumi. Salah satunya kelurahan lempuing yang terletak di daerah pesisir pantai panjang Kota Bengkulu yang berdekatan dengan pemukiman penduduk sekitar 2 meter yang  memiliki dampak getaran gempa sangat hebat saat terjadi gempa bumi. Tujuan penelitian ini adalah untuk mendeskripsikan kesiapsiagaan masyarakat di daerah lempuing terhadap bencana gempa bumi. Jenis penelitian ini adalah penelitian deskriptif, sampel pada penelitian ini adalah kepala keluarga yang diambil secara accidental sampling. Hasil penelitian menunjukkan sebagian besar responden 66% dengan kategori tidak siap dalam menghadapi bencana. Peneliti menyarankan kesiapsiagaan terhadap bencana perlu ditingkatkan dalam upaya meningkatkan kesiapan masyarakat dalam menghadapi bencana.
Pengaruh Terapi Bekam terhadap Penurunan Tekanan Darah pada Penderita Hipertensi di Pondok Pengobatan Alternatif Miftahusyifa
Authors: Sardaniah Sardaniah , Nurhasanah Hj , Marlena Feny
Published: April 2020

ABSTRAK Hipertensi adalah salah satu penyakit yang makin banyak dijumpai di Indonesia yang merupakan penyebab kematian  ketiga untuk semua umur  (7,4%).  Hipertensi  adalah  peningkatan  tekanan  darah  yang  melebihi tekanan  darah  normal,  sistol  lebih  dari  atau  sama  dengan  140  mmHg  dan tekanan diastol lebih dari atau sama dengan 90 mmHg. Penyakit ini merupakan faktor risiko yang besar untuk serangan jantung, stroke, dan gagal jantung. Tindakan  pencegahan  maupun  penanganan  sangat  penting  segera  dilakukan untuk Menghindari peningkatan penyakit hiepertensi di Indonesia. Pengobatan hipertensi dapat dilakukan dengan pengobatan farmakologis, nonfarmakologis dan komplementer. Penyakit hipertensi harus segera ditangani, salah satunya dengan  pengobatan  komplementer  yaitu  bekam.  Bekam  merupakan  suatu metode pengobatan penyakit dengan cara mengeluarkan angina atau darah kotor dari dalam tubuh melalui permukaan kulit. Tujuan penelitian ini adalah untuk mengetahui pengaruh terapi bekam terhadap tekanan darah pada pasien hipertensi.Metode penelitian ini menggunakan quasi experimental dengan one group pretest-posttest  design. Jumlah sampel  yang digunakan sebanyak 98 responden yang dilakukan di Pondok Pengobatan Alternatif   Miftahusyifa Kota Bengkulu  dengan  melakukan 1 kali intervensi bekam. Hasil  uji  statistik  ditemukan adanya  perubahan  pada tekanan  darah  yaitu terjadi penurunan dengan selisih nilai mean pada sistol (12,143) dan  diastol (8,265). Uji statistik yang menggunakan uji skewness pada sistol dan diastol menunjukan nilai (p=0,000) yang berarti nilai p<0,05 sehingga H1 diterima yang artinya menunjukan bahwa ada pengaruh yang signifikan terapi bekam terhadap perubahan tekan darah pada penderita hipertensi. Penelitian selanjutnya manfaat terapi bekam untuk penyakit lainnya dan dijadikan tindakan keperawatan pengobatan komplementer untuk pasien hipertensi yang dapat digunakan masyarakat.
Sistem Informasi Permintaan Fasilitas Teknologi Informasi Berbasis Web
Authors: Sudradjat Budi
Published: April 2020

Era globalisasi telah menunjukkan perkembangan yang sangat cepat. Manusia selalu berusaha untuk membuat inovasi teknologi informasi sesuai dengan kebutuhan. Dalam menciptakan suatu sistem informasi dengan implementasi yang sukses, seluruh elemen perusahaan wajib bekerja sama dalam mencapai target yang ingin dicapai. Dengan adanya sistem informasi permintaan fasilitas teknologi informasi yang berbasis web diharapkan dapat mengontrol permintaan fasilitas teknologi informasi dengan efektif dan dapat digunakan dengan sebaik-baiknya
Análise de eventos de inundação na sub-bacia do córrego Carneirinhos, João Monlevade, Minas Gerais
Authors: Silva Josiano Josiel Rodrigues , Oliveira Gisely de Assis , Monte-Mor Roberto Cezar de Almeida , Freitas Ana Carolina Vasques , Lima Fernando Neves
Published: April 2020

Desde a década de 1940 o número de pessoas que vivem nas cidades brasileiras dobrou, sendo que na maior parte delas o processo de crescimento ocorreu de modo desordenado, resultando em problemas socioambientais, inclusive inundações e deslizamentos de encostas nos períodos chuvosos. João Monlevade é um município mineiro que apresenta um histórico de desastres decorrentes de eventos hidrológicos extremos, assim, este estudo objetiva analisar os eventos de inundação registrados na sub-bacia do córrego Carneirinhos, seus respectivos impactos, bem como os sistemas meteorológicos atuantes no período de ocorrência. Primeiramente foi realizada a delimitação e caracterização da área de estudo, procedeu-se a coleta dos dados relacionados à série histórica dos eventos de inundações ocorridos na sub-bacia entre os anos de 1969 a 2020. Em seguida, identificaram-se os sistemas meteorológicos atuantes nas datas dos eventos. Pode-se constatar que o córrego Carneirinhos registrou 14 eventos de inundação que estão associados, principalmente, com a Zona de Convergência do Atlântico Sul ou com Zonas de Convergência de Umidade. Alguns possíveis fatores que podem justificar a ocorrência destes eventos são as alterações nos padrões hidrológicos devido às mudanças climáticas, a canalização do córrego, possíveis falhas no dimensionamento do projeto do sistema de drenagem da bacia, e/ou a combinação de todos estes fatores. Por fim, recomenda-se que sejam realizados estudos que avaliem o sistema de drenagem atual do município abordando o dimensionamento das galerias existentes frente às mudanças climáticas futuras, uma vez que alguns estudos apontam para um aumento na frequência dos eventos de inundação.
FAKTOR YANG MEMPENGARUHI KESELAMATAN BERKENDARA MOBIL DIRUAS JALAN TOL SEMARANG-BAWEN PROPINSI JAWA TENGAH
Authors: Sumantri Andar Sri , Misbahudin Irfan
Published: April 2020

Driving safety is influenced by various such as road conditions vehicle condition, driving behavior, knowledge of driving. All four have an important role in influencing the safety of driving. The purpose of this study was to determine whether there is influence of road conditions, vehicle conditions,driving behavior, knowledge of driving on roads Toll-Bawen Semarang Central Java Province either partially or simultaneously.
Results of statistical analysis tools SPSS (Statistical Product And Service Solutions) Ver. 22.0 multiple linear regression equation Y= 2,568 +0,268 X1 + 0,266 X2 + 0,216 X3 +0,148 X4 ( The results of multiple linear regression equation showed that there were significant positive influence on Keselamatan drive the road condition (t = 3,229> t tabel = 1,9853) the condition of vehicle on road safety (t =2,624> t tabel = 1,9853 the driving behavior of the safety driving (t = 3,037 > t tabel = 1,9853, drive to the road safety knowledge ( t = 2,139 > table = 1,9853) individually and simultaneously influence, vehicle conditions perilaku driving, and driving knowledge together –have the same effect as 26,529 > F Tabel 2,46. The fourth influence is very strong research variable with the coefficient of determination (R2) were obtained for 50,8 of the safety of driving and 49,2 % are influenced by variable that are not detectedin this study

Keywords : Road condition, Vehicle condition, Driving behavior, Knowledge of driving, and Driving safety.

 

Keselamatan berkendara dipengaruhi oleh berbagai factor diantaranya adalah kondisi jalan, kondisi kendaraan, perilaku pengendara, pengetahuan berkendara. Tujuan dari penelitian ini adalah untuk mengetahui ada tidaknya pengaruh antara kondisi jalan, kondisi kendaraan, perilaku pengendara, pengetahuan berkendara diruas jalan Tol Semarang Bawen Propinsi Jawa Tengah. Dalam penelitian ini yang menjadi populasi adalah pengguna mobil golongan I dijalan tol semarang bawen provinsi jawa tengah berjumlah 100 orang. Variabel dalam penelitian ini terdiri dari : Variabel bebas yaitu kondisi jalan x1, kondisi kendaraan perilaku berkendara x3 dan pengetahuan berkendar serta variable terikat yaitu keselamatan berkendara. Semua hipotesis yang diajukan dalam penelitian ini diterima, sehingga model tersebut mengambarkan hubungan yang kausalitas yang terjalin antar variable. Hasil analisi dengan alat bantu statistic program spss ver.22 . Dari hasil persamaan regresi linier berganda menunjukkan bahwa ada pengaruh yang positif dan signifikan antar masing-masing variable. Pengaruh keempat variable penelitian sangat kuat dengan nilai koefisien determinasi yang diperoleh sebesar 50,8% terhadap keselamatan berkendara dan 49,2 % dipengaruhi oleh variable yang tidak terdeteksi pada penelitian ini.

Kata kunci : Kondisi Jalan, Kondisi Kendaraan, Perilaku Berkendara, Pengetahuan berkendara dan Keselamatan berkendara.
PENGARUH STRATEGI PEMBELAJARAN RECIPROCAL TEACHING TERHADAP HASIL BELAJAR MATEMATIKA SISWA KELAS IV MI NIDHOMIYAH JOMBANG
Authors: Masruroh Faridatul , Syafrudin Tomi
Published: April 2020

Selection of appropriate learning strategies by teachers tailored to the subject matter, so that students can understand the subject clearly. Reciprocal Teaching is a learning strategy so that learning objectives are reached quickly through the process of independent learning. By presentation in front of a class, students are expected to achieve learning objectives and increase learning independence. This study aims to determine whether there is an influence of Reciprocal Teaching towards mathematics learning outcomes of fourth-grade students MI Nidhomiyah Jombang academic year 2018/2019. The calculation of the t-value uses SPSS 16. The result of t-value is 4,667 with sig (2 tailed)= 0,000. The data result showed that  is rejected. The researchers concluded that there is influence Reciprocal Teaching towards mathematics learning outcomes.
PENERAPAN MODEL PEMBELAJARAN KOOPERATIF NHT UNTUK MENINGKATKAN HASIL BELAJAR MATEMATIKA SISWA XI IPS 5 SMAN 12 PEKANBARU
Authors: Alfarobi  , Alirman
Published: April 2020

Penelitian ini merupakan penelitian tindakan kelas yang bertujuan untuk meningkatkan hasil belajar matematika siswa kelas XI IPS 5 SMA Negeri 12 Pekanbaru melalui model pembelajaran kooperatif tipe Numbered Heads Together (NHT) pada semester genap tahun pelajaran 2018/2019. Subjek penelitian adalah siswa kelas XI IPS 5 yang berjumlah 35 orang dengan kemampuan akademik yang heterogen. Pengumpulan data dilakukan melalui pengamatan dan tes hasil belajar matematika. Pengamatan dilakukan oleh satu orang guru matematika SMAN 12 dan satu orang dosen Pendidikan Matematika FKIP UNRI. Tes hasil belajar matematika dilakukan sebanyak dua kali di setiap akhir siklus. Instrumen pengumpulan data yang digunakan adalah lembar pengamatan aktifitas guru dan siswa serta soal tes hasil belajar matematika. Data aktifitas guru dan siswa dianalisis secara kualitatif dan data hasil belajar matematika dianalisis secara kuantitatif. Hasil penelitian menunjukkan bahwa aktifitas guru dalam menerapkan pembelajaran kooperatif tipe NHT sudah semakin sesuai dengan RPP dan mengalami peningkatan kualitas untuk setiap pertemuan. Demikian juga halnya dengan aktifitas siswa yang menunjukkan kemajuan untuk setiap pertemuan. Siswa sudah berani untuk maju ke depan kelas mempresentasikan hasil diskusi kelompoknya. Sejalan dengan peningkatan aktifitas guru dan siswa dalam pembelajaran, hasil belajar matematika siswa juga meningkat. Persentase siswa yang mencapai Kriteria Ketuntasan Minimal (KKM) untuk siklus I dan II adalah 14,28%, naik 8,58% sebelum dilakukan tindakan. Dengan demikian dapat disimpulkan bahwa terjadi peningkatan hasil belajar matematika dengan menerapkan model pembelajaran kooperatif tipe NHT.
Ways of Organizational and Methodological Development of Intra-Extramural Form of Study
Authors: Yakovleva E.
Published: April 2020

The article traces dynamics of the share of first-year students using intra-extramural form of study at the Nizhnekamsk Chemical Technological Institute of Kazan National Research Technological University. Advantages and disadvantages of bachelor training in an intra–extramural form of study are considered. The author dwells on the extension of students’ age brackets which is common for our country in recent years. Defining characteristics of teaching adults are revealed. Possible directions of organizational and methodological improvement of intra–extramural form of study in terms of professional training of bachelors in a higher educational institution are featured. Main aims solved by a lecturer are defined. Special attention is paid to developing the methodology of conducting micro-seminars during laboratory classes in physics which contributes to the active independent cognitive activity of students. Attention is drawn to the need for effective supervision during the midterm assessment.
Axiological Approach in the Sociology of Culture
Authors: Petrov I.
Published: April 2020

Since its inception, sociology has focused on the analysis of cultural patterns, patterns of functioning and development of society, and the search for optimal solutions to various socio–cultural problems. The article deals with the interpretation of culture based on its value understanding. Today, the axiological approach continues to play an important role in the sociology of culture. This allows us to study the structure of social values, as well as the dominant value orientations of diverse social groups, not only in the sphere of culture, but also in other areas of society. Based on these studies, practical recommendations can be developed on a wide range of cultural issues — from the moral education of young people, to the optimization of the activities of certain socio–cultural institutions.
Scientific Theory of Technological Structures and Research Directions of Its Practical Application
Authors: Glushchenko V.
Published: April 2020

Subject of the article is development of scientific theory, technological paradigms and research directions of its practical application, the object of study is technological way as a socio–economic and technological phenomenon, the aim of this work is to optimize the process of crisis management by accelerating the formation of the sixth technological structure in the economy to achieve this goal the following tasks: research the features and roles (entity) technological system in the real economy and social life; the scientific methods of the article are philosophy and methodology of science, functional and decomposition representation of complex systems, algebra of logic, search and normative forecasting, heuristic forecasting, expert methods, system approach, system analysis and synthesis, the scientific novelty of the work is associated with the development of the scientific theory of technological systems and the study of its practical use.
Basic Paradigmatic Correlations in the Semantic Field of the Concept Summer
Authors: Grudeva E.
Published: April 2020

Article is based on the materials of a comprehensive study of the concepts summer and autumn from the point of view of their perception by representatives of Russian and English linguistic cultures. This paper shows the features of the paradigmatic relations of Russian and English concept summer. The study was built on the identification of synonymous (quasi-synonymous), antonymic, (hypo) hyperonymic, or genus-species relationships, as well as the incompatibility relations of this concept. Study is based on the materials of the explanatory dictionaries and dictionaries of synonyms and antonyms of the Russian and English languages; illustrative material was taken from the National corpus of the Russian language and the British National Corpus. The analysis made it possible to conclude that the paradigmatic explication of the content of the concept summer most clearly actualizes only one of the four previously identified cognitive features of the concept, namely the sign ‘time of year, season’.
Linguo-cognitive and Linguo-cultural Analysis of the English Phraseological Units With the Fire Component
Authors: Mirjalilova M.
Published: April 2020

At present, special attention is paid in the cognitive linguistics to the problem of linguistic units that represent different knowledge structures. Phraseological units, being one of the core linguistic means of verbalization of different knowledge structures, are ought to be analyzed thoroughly. Further to this, idiomatic expressions and proverbs are vital signals in verbalization of cultural values and national specific concepts which leads to the necessity of linguo-cultural analysis of these units. This article is aimed to analyze phraseological units with the fire component in English language according to cultural and cognitive parameters and to identify cultural values and cognitive models that are presented by these expressions.
World Literature on the Destiny and Sufferings of Jewish People
Authors: Mukhamedova Sh.
Published: April 2020

The article considers the Holocaust reflection in world literature and popular authors as the best painters of the Holocaust repressions. Naturally, the Holocaust is a trauma which cannot ever be restored, a gap that cannot be bridged. Down to the present day, this remains an important topic for discussion. Despite the overwhelming persecution and death that surrounded the Jewish nation, hundreds of thousands of Jews survived the nightmare of the Holocaust. In order to integrate the past in their lives, survivors want to testify and/or write down their experiences. These stories of survival provide the only glimpse of ‘goodness’ that comes from the terrible story of the Holocaust. It proves that, even in history’s darkest hour, there was a glimmer of hope; that in a world that seemed to be falling apart, good still had the capacity to overcome evil. All stories written on the destiny and sufferings of the Jewish nation are worth analysis. However, we took only those which are in the form of confession. The chosen novels can be classified by the types of the central heroes and heroes have been divided into subgroups according to their age, nation, and, of course, the gender. The article aims to reaffirm the importance of the novels by using three literary approaches — historical, biographical and social. The biographical approach is taken for the analysis to identify the link between the work and the authors, who build a story on the basis of their own memories and real-life experience. Furthermore, the socio-historical problems highlighted in the novels are very relevant, since they still exist in modern societies in one or another form. The article reflects how even one novel encompasses morality, dignity, humanity issues and at the same time reveals the author’s position related to the indifference of the world regarding cruelty and evading responsibility for anti-human crimes along with how to avoid them in the near future.
Derivational Analysis of Terms of Computational Linguistics
Authors: Ermetova J. , Matyakubova N.
Published: April 2020

Describes the derivational analysis of the English terminology of computational linguistics. The study is conducted on a compilation of computer terms with a total volume of 744 units, compiled on the basis of computer and linguistic glossaries and dictionaries. The analysis was done based on the classification of L. Tkacheva. Made it possible to identify the most productive methods of term formation, as well as their structural types. The study may be of interest to researchers in the field of computational linguistics and translation activities.
PERAN KOMUNIKASI EFEKTIF PEMIMPIN DALAM MENINGKATKAN KINERJA INSTITUSI
Authors: Nasukah Binti , Sulistyorini Sulistyorini , Winarti Endah
Published: April 2020

This study aims to identify and understand two important things, namely; characteristics of effective communication of school principals and the role of effective communication of school principals in improving institutional performance. This research uses a qualitative approach to the type of library research, by collecting data from; books, kitab, journals, articles. Data analysis was performed using content analysis. Through the literature study, the results show that: first, there are six characteristics of effective communication of leaders: being gentle, not being rude in speech, not being stubborn, forgiving and asking for forgiveness, inviting deliberation, and committed to conducting joint decisions and resignation to Allah SWT. Second, effective communication leaders play a role in; 1) Increase the effectiveness in sharing the vision of the Mission; 2) Improving the performance of the staff in the teacher's specialty; 3) Establishing partnerships with the school community 4) building a conducive school climate; and 5) Increasing the students' achievements. The results implicates on the importance of leaders of Islamic institutions to have the characteristics of effective communication, so it can play a role in improving the performance of the Institution.
الطريقة السمعية الشفوية في ترقية مهارتي الاستماع والكلام
Authors: Aini Cicik
Published: April 2020

يهدف هذا البحث إلى وصف عملية تنفيذ الطريقة السمعية الشفوية في ترقية مهارتي الاستماع والكلام لدى طالبات مدرسة نور الجديد الثانوية الإسلامية بيطان بروبولنجو، وكشف مشكلات تنفيذ الطريقة السمعية الشفوية في ترقية مهارتي الاستماع والكلام وتقديم الحلول المطابقة في تنفيذ الطريقة السمعية الشفوية في ترقية مهارتي الاستماع والكلام فيها. واستخدمت الباحثة في هذا البحث المدخل الكيفي بالمنهج الوصفي التحليلي كما اختارت الباحثة المقابلة والملاحظة والوثائق في جمع البيانات.واستندت الباحثة في تحليل البيانات الى أسلوب ميلس وهبرمان. ونتائج البحث هي أن عملية تنفيذ الطريقة السمعية الشفوية في ترقية مهارتي الاستماع والكلام تُبدأ بترابط المدرس وإعطاء المادة كالحوار أو النصوص العربية أو الأفلام بوسيلة المسجل وسماع الحوار والتقليد والحفظ والتدريب على أنماط الكلمات والممارسة في الكلام أمام الفصل وينتهي التدريس بالسلام، والمشكلات في تنفيذ طريقة السمعية الشفوية في ترقية مهارتي الاستماع والكلام تتكون من المشكلات الداخلية والمشكلات الخارجية، والحلول في تطبيق طريقة السمعية الشفوية في ترقية مهارتي الاستماع والكلام هي تطوير مفاهم المعلم عن الطريقة السمعية الشفوية واختيار الموضوع المناسب لكل طبقة وتجهيز القاموس وفتح الشبكة الدولية والتدريبات والتمثيل وغير ذلك.
THE USE OF HYBRID/BLENDED LEARNING IN UNDERSTANDING OF ENGLISH STRUCTURE SUBJECT TO IMPROVE STUDENTS' ACHIEVEMENT AND THEIR DIGITAL LITERACY
Authors: Vonti Lungguh Halira , Rahmah Mursidah
Published: April 2020

This research is aimed to find out whether the aplication of blended learning has significant effect on the students' achievement of Understanding English Structure subject or not, and to know if the students' achievement after the application of blended learning is better than the prior knowledge of the subject.  It was also to see if the application of blended learning give positive effect to the students' digital literacy.   Hence, the researcher employs experimental research by giving hybrid-learning model as the treatment.  It is expected that the students can achieved good score about English structure. The research involves the second semester students of English Language Education Study Program of FKIP Pakuan University. They were chosen through purposive sampling technique. Based on the result of data analysis by using ANOVA, the students' achievement in strcture class was improved. Based on the t-test results it is known that the average pre-test is 63.4 and after treatment in the form of learning using a hybrid / blended learning model, the average post-test value becomes 86 so that the increase is 22.6. So that it can be stated there is a significant increase in student learning outcome scores by using hybrid / blended learning models. The positive result was also gained from the digital literacy questionnaire.  Most of the students' digital literacy was improved significantly at about 10 to 20%.  Therefore, it can be stated that hybrid-learning model can improve students' achievement in grammar class and also can improve their digital literacy.
TINJAUAN TEORETIK TENTANG KOMITMEN ORGANISASI GURU
Authors: Hidayat Rais
Published: April 2020

ABSTRACTTeachers' organizational commitment is the key to the implementation of quality education. Without high organizational commitment of teacher, the implementation of quality education is unlikely to materialize. Therefore, a clear description and conception of teachers' organizational commitment is needed. The purpose of this research is to describe the teachers' organizational commitment in depth decription. This research uses literature review method. The results of the research were then presented to answer the 3 research problems: the nature of teachers organizational commitment, the processes and factors that shaped the organizational commitment of teachers, and the ways to develop and enhance the organizational commitment of teachers.Keywords: organizational commitment, theoretical review, literature methodABSTRAKKomitmen organisasi guru merupakan kunci pelaksanaan pendidikan yang bermutu. Tanpa komitmen organisasi yang tinggi, pelaksanaan pendidikan bermutu tidak mungkin terwujud. Oleh karena itu, deskripsi dan konsepsi yang jelas tentang komitmen organisasi guru sangat diperlukan. Tujuan penelitin ini untuk mendeskripsikan komitmen organisasi guru secara lebih mendalam. Kajian teoretik ini menggunakan metode kajian literatur. Hasil kajian kemudian dipaparkan untuk menjawab 3 rumusan permasalahan penelitian yaitu: tentang hakikat komitmen organisasi guru, proses dan faktor-faktor yang membentuk komitmen organisasi guru, dan tentang cara-cara mengembangkan dan meningkatkan komitmen organisasi guru.Kata kunci: komitmen organisasi, tinjauan teoretik, metode literatur
AKTIVITAS KOLABORASI DAN KEMAMPUAN MENGEMBANGKAN GAGASAN DALAM MENULIS KALIMAT IKLAN PADA PEMBELAJARAN BAHASA INDONESIA DI SMPN 3 CIBINONG KABUPATEN BOGOR
Authors: Talitha Stella , Rosdiana Rina , Susilawati Rini
Published: April 2020

ABSTRACTThis research is based on student collaboration activities and the ability of students to develop ideas in writing advertising sentences. The formulation of the problem in this study is (1) How is the collaborative activity in learning Indonesian at Cibinong 3 Public Junior High School Bogor? (2) What is the result of the ability of students to develop ideas in writing advertising sentences in learning Indonesian at Cibinong 3 Public Junior High School Bogor? This study aims to describe: (1) collaborative activities on learning Indonesian at Bogor Cibinong 3 Junior High School (2) the results of students' ability to develop ideas in writing advertising sentences in Indonesian language learning at Bogor Cibinong 3 Junior High School. The method used in this research is the qualitative method. The results of this study in the form of collaborative activities on learning Indonesian at SMPN 3 Cibinong Bogor are as follows. a) identifying sentences of facts and opinions on products, b) giving ideas about sentences of facts and opinions, c) giving opportunities (taking turns, giving ideas about sentences of facts and opinions), d) discussing the answers of his group friends, e) utilizing time effectively, f) conveying ideas of facts and opinions in accordance with the product, and g) confirming the ideas of sentence facts and opinions recorded to group friends. The results of students' ability to develop ideas in writing ad sentences on learning Indonesian at Bogor Cibinong 3 Junior High School are good. This is based on data on the results of student skills, there are 32 data facts or correct sentences of 82.05% and 34 correct opinion sentence data or equal to 87.18%.Keywords: collaboration activities, advertising sentences, facts, opinions
SISI HUMOR DAN CITA RASA KHONG GUAN PADA PUISI-PUISI JOKO PINURBO
Authors: . Mukodas , Mubarock Wildan F.
Published: April 2020

HUMOR AND TASTE OF KHONG GUAN IN JOKO PINURBO’S POEMJoko Pinurbo is one of productive writer. The most interesting part of all works from Jokpin is the humour or jokes he inserted. What makes it interesting there are several poems that he wrote which published in Kompas newspaper on 31st Agustus 2019. There are twelve poems which consists the word Khong Guan in every title: Perjamuan Khong Guan, Hujan Khong Guan, Tidur Khong Guan, Lebaran Khong Guan, Minuman Khong Guan, Sabda Khong Guan, Agama Khong Guan, Keluarga Khong Guan, Mudik Khong Guan, Doa Khong Guan, Bingkisan Khong Guan, dan Hati Khong Guan. Those twelve poems are the subject to this research. The aim of this research is to define how humor was created.  Recent humors are mostly uneducated humor such as insult joke, bullying, and disrespectful. Joko Pinurbo gives alternative in doing humor, through poem. Humor found in the poem is dominated by tragedy humor. Descriptive qualitative method is used in this research. This research found that there are five poems which can be classified as tragedy
The Effect of Dietary Helianthus tuberosus L. on the Populations of Pig Faecal Bacteria and the Prevalence of Skatole
Authors: Okrouhlá Monika , Čítek Jaroslav , Švejstil Roman , Zadinová Kateřina , Pokorná Kamila , Urbanová Daniela , Stupka Roman
Published: April 2020

Jerusalem artichoke contains inulin polysaccharide, which has prebiotic effects and influences the microbiota of the digestive tract. The addition of Jerusalem artichoke in boar diets may decrease the content of skatole and indole, which are the main constituents of boar taint, and may also negatively affect the taste and odor. The objective of this study was to evaluate the effects of different levels of Helianthus tuberosus L. (H. tuberosus) in feed mixtures on performance, carcass composition, the levels of microbiota in faecal samples, and the concentrations of skatole and indole in adipose tissue. The study was performed with 47 crossbred entire male pigs of the Large White sire × (Large White dame × Landrace) genotype fed a basal diet with 0%, 4.1%, 8.1% or 12.2% H. tuberosus for 13 days before slaughter. Significant differences in daily weight gain and daily feed intake were found (p = 0.045), with the values being lower in the group with the highest level of H. tuberosus. In addition, increasing levels of H. tuberosus decreased the concentration of skatole in the adipose tissue (p = 0.003). The highest level of H. tuberosus decreased the level of Escherichia coli (p ≤ 0.001) in the faeces. The enterococcal count increased (p = 0.029) in groups with a diet that included 4.1% and 8.1% H. tuberosus. There was also a significant correlation between the concentration of H. tuberosus and the concentration of E. coli (p < 0.001; −0.64) and the skatole levels in the adipose tissue (p = 0.001; –0.46). Moreover, there was also a positive correlation between the concentration of E. coli and the skatole levels in the adipose tissue (p = 0.023; 0.33). In conclusion, feeding pigs with H. tuberosus leads to decreased levels of skatole in the adipose tissue. According to the results of our study, a diet with 8.1% H. tuberosus is sufficient for decreasing skatole levels, which could be due to the decreased levels of pathogenic bacteria in the intestines.
Potential Benefits of Nrf2/Keap1 Targeting in Pancreatic Islet Cell Transplantation
Authors: Jarrin Lopez Alberto , Lau Hien , Li Shiri , Ichii Hirohito
Published: April 2020

Permanent pancreatic islet cell destruction occurs in type 1 diabetes mellitus (T1DM) through the infiltration of inflammatory cells and cytokines. Loss of β-cell integrity secondary to oxidation leads to an inability to appropriately synthesize and secrete insulin. Allogenic islet cell transplantation (ICT) has risen as a therapeutic option to mitigate problematic hypoglycemia. Nevertheless, during the process of transplantation, islet cells are exposed to oxidatively caustic conditions that severely decrease the islet cell yield. Islet cells are at a baseline disadvantage to sustain themselves during times of metabolic stress as they lack a robust anti-oxidant defense system, glycogen stores, and vascularity. The Nrf2/Keap1 system is a master regulator of antioxidant genes that has garnered attention as pharmacologic activators have shown a protective response and a low side effect profile. Herein, we present the most recently studied Nrf2/Keap1 activators in pancreas for application in ICT: Dh404, dimethyl fumarate (DMF), and epigallocatechin gallate (EGCG). Furthermore, we discuss that Nrf2/Keap1 is a potential target to ameliorate oxidative stress at every step of the Edmonton Protocol.
Special Issue on New Horizons in Time Domain Diffuse Optical Spectroscopy and Imaging
Authors: Hoshi Yoko
Published: April 2020

In 1977, Jöbsis first described the in vivo application of near-infrared spectroscopy (NIRS) [...]
Hypoxia Inducible Factors’ Signaling in Pediatric High-Grade Gliomas: Role, Modelization and Innovative Targeted Approaches
Authors: Fuchs Quentin , Pierrevelcin Marina , Messe Melissa , Lhermitte Benoit , Blandin Anne-Florence , Papin Christophe , Coca Andres , Dontenwill Monique , Entz-Werlé Natacha
Published: April 2020

The brain tumor microenvironment has recently become a major challenge in all pediatric cancers, but especially in brain tumors like high-grade gliomas. Hypoxia is one of the extrinsic tumor features that interacts with tumor cells, but also with the blood–brain barrier and all normal brain cells. It is the result of a dramatic proliferation and expansion of tumor cells that deprive the tissues of oxygen inflow. However, cancer cells, especially tumor stem cells, can endure extreme hypoxic conditions by rescheduling various genes’ expression involved in cell proliferation, metabolism and angiogenesis and thus, promote tumor expansion, therapeutic resistance and metabolic adaptation. This cellular adaptation implies Hypoxia-Inducible Factors (HIF), namely HIF-1α and HIF-2α. In pediatric high-grade gliomas (pHGGs), several questions remained open on hypoxia-specific role in normal brain during gliomagenesis and pHGG progression, as well how to model it in preclinical studies and how it might be counteracted with targeted therapies. Therefore, this review aims to gather various data about this key extrinsic tumor factor in pHGGs.
Betulinic Acid-Mediated Tuning of PERK/CHOP Signaling by Sp1 Inhibition as a Novel Therapeutic Strategy for Glioblastoma
Authors: Lo Wei-Lun , Hsu Tsung-I , Yang Wen-Bin , Kao Tzu-Jen , Wu Ming-Hsiao , Huang Yung-Ning , Yeh Shiu-Hwa , Chuang Jian-Ying
Published: April 2020

Patients with glioblastoma are at high risk of local recurrences after initial treatment with standard therapy, and recurrent tumor cells appear to be resistant to first-line drug temozolomide. Thus, finding an effective second-line agent for treating primary and recurrent glioblastomas is critical. Betulinic acid (BA), a natural product of plant origin, can cross the blood–brain barrier. Here, we investigated the antitumor effects of BA on typical glioblastoma cell lines and primary glioblastoma cells from patients, as well as corresponding temozolomide-resistant cells. Our findings verified that BA significantly reduced growth in all examined cells. Furthermore, gene-expression array analysis showed that the unfolded-protein response was significantly affected by BA. Moreover, BA treatment increased activation of the protein kinase RNA-like endoplasmic reticulum kinase (PERK)/C/EBP homologous protein (CHOP) apoptotic pathway, and reduced specificity protein 1 (Sp1) expression. However, Sp1 overexpression reversed the observed cell-growth inhibition and PERK/CHOP signaling activation induced by BA. Because temozolomide-resistant cells exhibited significantly increased Sp1 expression, we concluded that Sp1-mediated PERK/CHOP signaling inhibition protects glioblastoma against cancer therapies; hence, BA treatment targeting this pathway can be considered as an effective therapeutic strategy to overcome such chemoresistance and tumor relapse.
Zika Virus Infects Human Placental Mast Cells and the HMC-1 Cell Line, and Triggers Degranulation, Cytokine Release and Ultrastructural Changes
Authors: Rabelo Kíssila , Gonçalves Antônio José da Silva , Souza Luiz José de , Sales Anna Paula , Lima Sheila Maria Barbosa de , Trindade Gisela Freitas , Ciambarella Bianca Torres , Amorim Tasmo Natália Recardo , Diaz Bruno Lourenço , Carvalho Jorge José de , Duarte Márcia Pereira de Oliveira , Paes Marciano Viana
Published: April 2020

Zika virus (ZIKV) is an emergent arthropod-borne virus whose outbreak in Brazil has brought major public health problems. Infected individuals have different symptoms, including rash and pruritus, which can be relieved by the administration of antiallergics. In the case of pregnant women, ZIKV can cross the placenta and infect the fetus leading to congenital defects. We have identified that mast cells in the placentae of patients who had Zika during pregnancy can be infected. This led to our investigation on the possible role of mast cells during a ZIKV infection, using the HMC-1 cell line. We analyzed their permissiveness to infection, release of mediators and ultrastructural changes. Flow cytometry detection of ZIKV-NS1 expression 24 h post infection in 45.3% of cells showed that HMC-1 cells are permissive to ZIKV infection. Following infection, β-hexosaminidase was measured in the supernatant of the cells with a notable release at 30 min. In addition, an increase in TNF-α, IL-6, IL-10 and VEGF levels were measured at 6 h and 24 h post infection. Lastly, different intracellular changes were observed in an ultrastructural analysis of infected cells. Our findings suggest that mast cells may represent an important source of mediators that can activate other immune cell types during a ZIKV infection, which has the potential to be a major contributor in the spread of the virus in cases of vertical transmission.
Cathepsins in the Pathophysiology of Mucopolysaccharidoses: New Perspectives for Therapy
Authors: De Pasquale Valeria , Moles Anna , Pavone Luigi Michele
Published: April 2020

Cathepsins (CTSs) are ubiquitously expressed proteases normally found in the endolysosomal compartment where they mediate protein degradation and turnover. However, CTSs are also found in the cytoplasm, nucleus, and extracellular matrix where they actively participate in cell signaling, protein processing, and trafficking through the plasma and nuclear membranes and between intracellular organelles. Dysregulation in CTS expression and/or activity disrupts cellular homeostasis, thus contributing to many human diseases, including inflammatory and cardiovascular diseases, neurodegenerative disorders, diabetes, obesity, cancer, kidney dysfunction, and others. This review aimed to highlight the involvement of CTSs in inherited lysosomal storage disorders, with a primary focus to the emerging evidence on the role of CTSs in the pathophysiology of Mucopolysaccharidoses (MPSs). These latter diseases are characterized by severe neurological, skeletal and cardiovascular phenotypes, and no effective cure exists to date. The advance in the knowledge of the molecular mechanisms underlying the activity of CTSs in MPSs may open a new challenge for the development of novel therapeutic approaches for the cure of such intractable diseases.