bluuebunny/crossref_metadata_2025 huggingface dataset:
Gamification in preschool science education
Authors:   Department of Preschool Education, University of Crete, Crete, Greece, Xezonaki Aikaterini
Published: May 2022

Over the last few years, rapid technological progress has developed our lives in all areas. The adoption of technology in the everyday lives of both adults and children through smart mobile devices has led to the foreseeable integration of digital tools in the educational process. Smart mobile devices and the applications that accompany them have been proven effective in the educational field since they allow students to acquire knowledge through activities with an interactive and playful character. A technique that has gained popularity among technology users in the last decades is gamification. Gamification combines mechanisms and elements of games, enhancing students' learning, motivation, and interest in various educational fields, such as mathematics and science. The usage of game elements in education is not encountered for the first time due to the spread of gamification in technology, but it has been mentioned since the early ancient Greek years. However, technology has reinforced gamification through components and techniques that provide students with all the necessary supplies leading to positive learning outcomes. This bibliographic review presents the literature findings on gamification through smart mobile devices in science teaching in preschool education.
Political competitors of the German minority in local and parliamentary elections in the years 1990-2019 in Opole Province
Authors: Kownacka Katarzyna
Published: May 2022

The German minority has been successfully putting up candidates in local and parliamentary elections in the Opole Voivodeship since the 1990s. It has its representatives on all levels of local government in the region, as well as in the Polish parliament. In many local governments in Opolskie Province - including at the regional level - it co-manages, and in some communes and districts it exercises authority. In subsequent elections for more than three decades it has been competing for votes with political parties, regional or local committees, as well as with committees referring to ethnic issues, in Opolskie Province - silesian. The aim of this article is to indicate which of these committees are main political rivals of German minority at the level of municipalities, districts, regional assembly and in parliamentary elections in the Opolskie province. In order to determine this, the aggregated results of political groups, local committees and committees relating to ethnic issues were compared and analyzed with the results of the minority committee at the different levels of local government and in parliamentary elections. The research used research methods such as quantitative-qualitative analysis, case study, descriptive analysis, comparative analysis and desk research. In order to deepen the issues, to better understand them, as well as to confront information from data source and literature about political competitors, activists of the German minority were also asked in IDI interviews.
Surveillance and guidelines update process at NICE
Authors: Shukla Kriti , McGuire Hugh , Dominguez Pilar Pinilla
Published: May 2022

The discoveries, new body of evidence, interventions, and new knowledge are inherent to science. Therefore, guidelines and recommendations also need to be under constant surveillance to update and embrace the new evidence, resulting in improved quality and safety. This article covers the process and decision-making process around the guidelines. The article captures the essence of discussion in the knowledge exchange seminar series between national institute for health and care excellence (NICE) and IHOPE, which was organized as a part of the collaborative project between NICE International and IHOPE to develop and implement evidence-based clinical guidelines in India. This paper is the fourth in the series, and further information on the other papers can be found at this link.
Screening for angle-closure disease in the community: A review
Authors: Philip Reni , Baskaran Mani , Vijaya Lingam , George Ronnie
Published: May 2022

Primary angle-closure glaucoma (PACG) has a higher risk of association with blindness compared to primary open-angle glaucoma. Early determination of PAC disease (PACD) before progression to PACG can help prevent loss of vision. Although gonioscopy is the gold standard for the determination of angle status, it requires more training and experience and may not be feasible to use for screening. We reviewed the performance of other modalities of angle assessment in population studies in comparison with gonioscopy. Assessment of limbal anterior chamber depth, biometric parameters such as central anterior chamber depth, lens thickness, axial length measurements, and anterior segment optical coherence tomography were used to qualitatively and quantitatively assess the angle structures in these studies. The sensitivity, specificity, and predictive values varied widely due to the use of varying techniques and definitions. A combination of more than 1 parameter was found to give better results in comparison with gonioscopy in some studies. Individual or combination tests most appropriate for screening need to be determined and reassessed by further well-controlled studies with uniform criteria.
Eye care and the carbon foot print
Authors: Ravilla Thulasiraj , Rengaraj Venkatesh , Balakrishnan N. , Ravilla Sriram
Published: May 2022

Objectives:

Climate change and its impact on the environment are rapidly becoming a crisis, resulting in extreme climate conditions and directly impacting health. The World Health Organization attributes 13.7 million deaths in 2016 to overall environmental factors. As health-care providers, we seem to be a significant contributor to carbon emissions. Health Care Without Harm, an organization promoting environmental health and justice, estimates that health-care accounts for an equivalent to 4.4% of global net carbon emissions. As a specialty with very high surgical volume, eye care would be contributing a significant portion of these carbon emissions. Thus, there is a need for us to explore ways of mitigating this.

Materials and Methods:

A descriptive case study method has been adopted to study environmentally sustainable practices with published or real-world data. Data from power consumption and energy audits were used in the analysis. The various approaches to reducing carbon emissions in eye care were studied using a broad framework of looking at what resources are deployed and how those resources are used.

Results:

Whether it is resources or how they are put to use, there is a great scope for reducing carbon emissions through reducing use, re-use, and recycling. On the energy front just through the use of energy efficient electrical devices, and 8%–10% reduction in power consumption could be achieved immediately. Since green energy is less expensive than grid power, switching to it can generate another 15% in cost savings. It was feasible to switch to green energy for 75% of the power needs in the larger hospitals. Organic water recycling technology could recycle over 90% of the water and re-used it. Lean clinical protocols showed that the carbon emissions could be reduced to 5% of what it is in the west for procedures like phacoemulsification.

Discussion:

While it is inevitable that eye care delivery will generate carbon emissions, it is well within our control to minimize it, per unit of care. This could be achieved essentially by minimizing waste or underutilization, enhancing efficiency, reducing consumption, and reducing patients’ efforts.

Conclusion:

These are the early days of trying to figure out, how the eye care sector can change its practices to minimize carbon emissions. A lot more evidence is required, signaling the need for research and publications in this space. As with any activity, for continuous improvement, we need benchmarks and robust monitoring systems. All of these are yet to evolve in clinical care.
Plain X-ray findings of post sleeve gastrectomy gastric leak
Authors: Alharbi Sultan R
Published: May 2022

Gastric leak following sleeve gastrectomy (SG) is a rare but significant cause of morbidity and mortality. A high clinical index of suspicion is the most sensitive approach to detect gastric leaks. Computed tomography (CT) is the gold standard diagnostic technique, although it might not be performed due to unavailability, and the inability to image superobese patients due to limited CT gantry space. Early detection and management are critical for attaining a better prognosis.

The following pictorial review discusses the various plain X-ray radiographic findings that indicate a gastric leak. These findings may be overlooked, however, they remain valuable in patients with clinically suspected gastric leaks. This pictorial review illustrates the spectrum of findings related to post-SG gastric leak encountered in plain X-ray radiography.
Seeking graduation in medical colleges outside India: Is it a ‘win–win’ or ‘lose–lose’ situation for the stakeholders and the nation?
Authors: VANIKAR A.V. , KUMAR V. , MINTZ M. , CHAKRABORTY D.
Published: May 2022

The future of Indian students who return as ‘foreign medical graduates’ (FMG) after training in certain countries is often uncertain. We collected data from newspapers, government resources and agencies involved in handling this issue. We analysed the current status of medical education in India, the Commonwealth of Independent States (CIS) and some neighbouring countries. Of approximately 1.4 million (14 lakh) students taking the National Eligibility cum Entrance Test (NEET), about 5.8% get admission in medical colleges. There are about 554 medical colleges in India with 82 550 MBBS seats, 51.9% seats belong to the government quota. Parents who send their children to a foreign country to do medicine spend ₹1.5 million (15 lakh) tò4 million (40 lakh) against an estimated annual income of ₹1.2 million (12 lakh) and the child spends 4–6 years in a foreign country. Of 38 150 FMGs who took the examinations conducted by the National Board of Examinations from 2015 to 2018, 18.9% passed the FMG examination mandatory for registration to practise medicine in India. The National Medical Commission is trying to solve this issue by removing the age bar for entry to MBBS and recommending lowering of fees for MBBS in government quota. Seeking graduation in medical colleges outside India may not be advisable for those from the middle/ low-income group of India.
Video consultations from an Indian academic hospital: First 3 years of experience from telepsychiatric after-care clinic
Authors: MATH SURESH BADA , NAGENDRAPPA SACHIN , MUKKU SHIVA SHANKER REDDY , HARSHITHA NISHA R. , VENU MEKALA A. , MANJUNATHA NARAYANA , KUMAR CHANNAVEERACHARI NAVEEN , SIVAKUMAR PALANIMUTHU THANGARAJU , THIRTHALLI JAGADISHA
Published: May 2022

Background

Continuity of care for psychiatric disorders by conventional in-person consultation by psychiatrists is associated with several challenges. There is a need to develop alternative models of specialist care. We studied our 3 years’ experience of live video consultations (VCs) from the tele after-care clinic to patients with psychiatric disorders at an Indian academic hospital.

Methods

We did a file review of 669 VCs provided to 213 patients in the first 3 years (2017–2019) from the telemedicine centre of a tertiary care academic hospital. We analysed details of sociodemography, clinical profile, tele after-care consultations and outcome.

Results

Two hundred and thirteen patients (55% men) were enrolled for the tele after-care clinic. The mean (SD) age of the patients was 42.2 (17.29) years and a majority were educated till high school and beyond. Patients with severe and common mental disorders constituted 60.1% and 40%, respectively. Among the total 669 appointments, 542 (81%) VCs were successfully provided; of the remaining, 125 were cancelled and 2 were aborted due to a medical emergency. Medication prescriptions were unchanged in 499 and modified/totally changed in 47 VCs.

Conclusion

Our large study shows that telepsychiatric after-care is a useful alternative method which can supplement in-person follow-up. Barriers such as distance, cost and medical illness can be overcome using tele after-care clinics for regular follow-ups in stabilized psychiatric patients. There is a need for prospective studies, preferably, randomized controlled trials comparing effectiveness of tele after-care with in-person consultations to assess treatment outcomes.
Psychometric analysis and construct validation of Health Professional Education in Patient Safety Survey in the Indian context
Authors: WUNDAVALLI LAXMITEJ , HUSSAIN MANSOOR , GUPTA ANANT , ARYA SANJAY KUMAR
Published: May 2022

Background

Improving patient safety (PS) is critical to optimizing healthcare delivery. There is a need to develop curricula or incorporate PS concepts in health professionals’ (HPs) education, in both theoretical and practical training. Consequently, there is a need to measure the perception of HPs regarding various PS competencies imparted to them during their training. The Health Professional Education in Patient Safety Survey (H-PEPSS) is a tool that measures HPs’ self-reported PS competence and was designed to reflect six sociocultural areas central to PS. The tool has been validated in Canada but not in India. We did a confirmatory factor analysis (CFA) and psychometric validation of the H-PEPSS in the Indian context.

Methods

The sample comprised 240 HPs. We used the maximum likelihood estimation method on AMOS V20 (SPSS Inc.) to carry out a CFA of the tool. We used the normed fit index, Tucker–Lewis index, comparative fit index, standard root mean square residual, root mean square residual and root mean square error of approximation to evaluate the model fit. Internal consistency and reliability of the six factors of the model were examined using Cronbach’s alpha. Convergent validity of the model was examined using average variance extracted and composite reliability. Discriminant validity was examined using the Fornell and Larcker criterion and the heterotrait–monotrait method.

Results

The results indicate a good fit. The H-PEPSS was found to be reliable and valid for assessing PS competencies among HPs. Comparison of the results with the results of the Canadian setting confirmed external validity.

Conclusion

The 16-item H-PEPSS has good psychometric properties for use in the Indian context. The 23-item HPEPSS was found to be reliable and valid for assessing PS.
Clinical variants of peripheral uveitis in children and their complications
Authors:   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk branch,  Khabarovsk , Russian Federation, Li V.V. , Kashura O.I. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk branch,  Khabarovsk , Russian Federation
Published: May 2022

Purpose. To study the frequency and structure of complications of peripheral uveitis (PU) in children who were hospitalized in the Khabarovsk branch of The S. Fyodorov Eye Microsurgery Federal State Institution in the period from 2015 to 2020. Material and methods. The object of the study were 20 children (40 eyes) with bilateral chronic recurrent PU. In addition to standard examination methods, optical coherence tomography (OCT) was performed. And to clarify the etiological diagnosis of PU, laboratory examinations and examinations by specialists of a narrow profile were carried out. Results. The results of enzyme immunoassay showed the presence of IgG to the herpes simplex virus in 14 patients (70 %), IgG to the Epstein-Barr virus - 12 patients (60 %), IgG to cytomegalovirus – 15 patients (75 %). Two children were found to be infected with Toxoplasma gondii (IgG) and Chlamydia trachomatis (IgG). The results obtained show a significant role of herpesvirus infections in the development of PU in children. In a prospective observation, the most common complication was unilateral or bilateral complicated cataract (8 eyes – 20 %). In 4 eyes – 10 %, according to OCT, cystic macular edema was detected. Traction retinal detachment was diagnosed in 2 eyes of one 15-year-old child. Conclusion. It was found that the main etiological cause of PU was herpesvirus infection. Complicated cataract was the most frequent complication of PU (20 %). The results of the conducted studies are of practical importance for the development of rational treatment tactics in children with PU. Keywords: peripheral uveitis, complications, childhood, etiology.
Eye lesion in Lyell’s Syndrome after COVID-19 vaccination (a clinical case)
Authors:   Ufa Eye Research Institute of the Academy of Sciences of the Republic of Bashkortostan,  Ufa, Russian Federation, Babushkin A. , Ilyina D. ,   Ufa Eye Research Institute of the Academy of Sciences of the Republic of Bashkortostan,  Ufa, Russian Federation, Israfilova G. ,   Ufa Eye Research Institute of the Academy of Sciences of the Republic of Bashkortostan,  Ufa, Russian Federation, Nikitina A. ,   Ufa Eye Research Institute of the Academy of Sciences of the Republic of Bashkortostan,  Ufa, Russian Federation
Published: May 2022

Lyell’s syndrome or toxic epidermal necrolysis is one of the most severe diseases of a toxic-allergic nature (most often for drug therapy) that pose a real threat to life. The article presents the data of a brief literature review and our personal clinical observation of Lyell’s syndrome with a description of the developed ophthalmopathology (keratoconjunctivitis, iridocyclitis, simblefaron, trichiasis and dry eye syndrome) in a 26-year-old patient. The etiological cause of the disease was most likely the administration of a new vaccine for the prevention of coronavirus infection COVID-19, commonly used in the last two years in connection with the pandemic. The complexity of managing such patients is due to the need to create special care conditions, prescribe timely and qualified therapy. The consequences and complications of this syndrome from various human body systems and organs, including eyes, are very diverse and very serious, and their treatment takes months or even years. Medical specialists should remember that many medications, as well as vaccines, which are currently used very widely and intensively in connection with the COVID-19 pandemic, can cause not only allergic reactions, for example anaphylactic shock, but also the development of toxic epidermal necrolysis. Keywords: COVID-19 prevention, vaccination, toxic epidermal necrolysis, Lyell’s syndrome, eye lesion.
Frequency and outcomes of burn injuries of the organ of vision
Authors:   Far Eastern State Medical University, Khabarovsk, Russian Federation, Pyatyshina O.V. , Shalaeva E.Y. ,   City Hospital no 9 under the Health Ministtry of Khabarovsk Territory,  Komsomolsk-on-Amur, Russian Federation, Kostiv V.Y. ,   Far Eastern State Medical University, Khabarovsk, Russian Federation
Published: May 2022

Purpose. Study of the structure, functional outcomes of burn injuries of the organ of vision in patients receiving inpatient treatment in an ophthalmological clinic. Material and methods. A continuous sample of patients with burns of the eyes and its appendages hospitalized in the ophthalmological department for 2017 and 2019. Results. 42 patients were hospitalized in the ophthalmology department, including 12 children under 18 years of age. The largest proportion was the age group from 30 to 50 years (51 %). Men predominated – 30 people (72 %). Thermal burns were in 5 patients (12 %). 37 patients (88 %) had chemical burns. All patients had corneal burns, in particular I degree in 19 people, II degree in 16 people, III degree in 7 people. The burn of the conjunctiva of the eyeball and the conjunctiva of the eyelids was noted in all eyes. Treatment of severe burns was carried out in accordance with the stages of burn injury. Conclusion. During the study period, there were 42 cases of eye burn injuries among residents of Khabarovsk and the Khabarovsk Territory, of which 12 were children under 18 years of age. All of them required hospital treatment. Keywords: thermal, chemical burns of the eye, severity of burn injury to the eyes.
Possibilities of using low-energy laser parameters with SMILE
Authors:   S. Fyodorov «Eye Microsurgery» Federal State Institution, St. Petersburg branch,  St. Petersburg, Russian Federation, Boiko E.V. ,   North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russian Federation,   Federal State Budgetary Military Educational Institution of Higher Professional Education  «Military Medical Academy named after S.M. Kirov», St. Petersburg, Russian Federation, Titov A.V. ,   S. Fyodorov «Eye Microsurgery» Federal State Institution, St. Petersburg branch,  St. Petersburg, Russian Federation, Mirsaitova D.R. ,   S. Fyodorov «Eye Microsurgery» Federal State Institution, St. Petersburg branch,  St. Petersburg, Russian Federation
Published: May 2022

Purpose. To study the influence of various laser energy parameters on the refractive result and the terms of visual rehabilitation of patients in the correction of myopia using SMILE. Material and methods. 120 patients (120 eyes) with moderate myopia, in some cases with myopic astigmatism, operated on using SMILE. Divided into 4 groups depending on the energy level applied during the operation (130–160 nJ). Patients underwent complete ophthalmic examinations preoperatively and over 3 months postoperatively. Results. A statistically significant increase in UCVA was obtained in the group with an energy of 130 nJ from 0,09±0,05 to 1,02±0,06 on the first day after surgery and up to 1,17±0,06 after 1 week. The use of low laser energies didn’t lead to an increase in HOAs. The black spots & areas: 1 – 3,33% (4), 2 – 3,33% (4), 3 – 4,17% (5), 4 – 8,33% (10 eyes). The largest number of cases of OBL formation was noted in group 1 (160 nJ) – 40% (12), 2 – 26% (8), 3 – 17% (5), 4 – 7% (2 eyes). The actual residual stromal thickness (OCT) after SMILE was 78,32%±0,02, 78,76%±0,02, 78,81%±0,02, and 79,23%±0,02 in each of groups in accordance with the applied energy (no significant differences). Conclusion. The use of low laser energies in SMILE contributes to a rapid recovery of vision in the early postoperative period with less energy impact on the corneal tissue, which allows to obtain a better surface without OBL, rapid healing and restoration of corneal thickness after correction. Keywords: SMILE, myopia, lower laser energy levels of femtosecond laser, OBL, Black spots & Areas.
Clinical evaluation of the effectiveness of the algorithm for predicting an increase in iop after phacoemulsification in patients with primary open-angle glaucoma
Authors:   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk иranch, Khabarovsk, Russian  Federation, Postupaeva N.V. , Sorokin E.L. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk иranch, Khabarovsk, Russian  Federation,   Far Eastern State Medical University, Khabarovsk, Russian Federation, Postupaev A.V. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk иranch, Khabarovsk, Russian  Federation, Pashentsev I.E. ,   The S. Fyodorov Eye Microsurgery Federal State Institution, the Khabarovsk иranch, Khabarovsk, Russian  Federation
Published: May 2022

Purpose. To evaluate the clinical effectiveness of the algorithm for predicting the risk of increased intraocular pressure (IOP) after phacoemulsification (PE) in patients with primary pen-angle glaucoma (POAG). Material and methods. 103 patients (103 eyes) with POAG who underwent PE were studied. The level of IOP according to Maklakov before the operation was 18.7±1.9 mm Hg. To identify the risk of an increase in IOP after PE, a prediction algorithm was used, with the help of which significant predictors were selected, logistic regression coefficients were determined, and the cut-off point for making prediction decisions was determined using ROC analysis. A favorable prognosis (without an increase in IOP) was given to 81 patients, an unfavorable prognosis (an increase in IOP to intolerant values) was given to 22 patients. Results. In the course of dynamic observation for 24 months, 20 cases of an increase in the level of IOP to intolerant values were identified. In 2 patients with a poor prognosis, there was no increase in IOP during the entire follow-up period. The specificity of the forecast was 90 % (20 out of 22). Conclusion. The developed predictive algorithm is reasonable and effective, its specificity is 90 %. When predicting the risk of an increase in IOP in the postoperative period of PE, patients with POAG should be carefully monitored postoperatively. This will provide an individual strategy for managing the patient to preserve visual functions. Keywords: primary open-angle glaucoma, phacoemulsification, intraocular pressure, prediction algorithm.
Kültürel ve kurumsal mesafenin ihracat üzerine etkisi: Türkiye örneği
Authors: TOHUM Enes Uğur , DEMİREL Yavuz
Published: May 2022

Küreselleşmenin son zamanlarda hız kazanması ile birlikte ülkeler arasındaki sermaye hareketliliği de oldukça önemli hale gelmiştir. Bu noktada gelişmiş ülkelerin belli başlı alanlarda avantajları olmasına rağmen; gelişmekte olan ülkelerin ekonomik gelişimlerini gerçekleştirmek adına daha atılgan bir rol üstlenmesi beklenmektedir. İşletmelerin ticari faaliyetlerini ulusal alanlardan uluslararası alanlara taşıması ile başlayan uluslararasılaşma hareketi; uluslararası ticarette ilgi gören bir konudur. Bu konu üzerinde, işletmelerin uluslararasılaşması bağlamında sıklıkla çalışılan, gelişmiş ülke odaklı çalışmaların yanında gelişmekte olan ülke odaklı çalışmaların yapılması da oldukça önemlidir. Bu kapsamda çalışmanın amacı Türkiye bağlamında kültürel ve kurumsal mesafenin ihracat üzerine etkisini tespit etmektir. Çalışmada ayrıca kültürel ve kurumsal mesafenin doğrudan etkisinin yanı sıra alt boyutlarının bağımlı değişken üzerindeki etkisinin incelenmesine odaklanılmaktadır. Bu bağlamda bağımsız değişkenler çerçevesinde Türkiye’nin ihracat gerçekleştirdiği 75 ülke örneklem olarak belirlenmiştir. Çalışmada bağımlı değişken olarak uluslararasılaşma stratejilerinden biri olan ihracat verileri dikkate alınmıştır. Çalışmada bağımsız değişkenin bağımlı değişken üzerinde etkisinin test edilebilmesi için iki ana hipotez belirlenmiş ve Türkiye bağlamında çalışma tasarlandığından dolayı ülkelerin gelişmişlik durumları göz önüne alınarak üçüncü hipotez ortaya konulmuştur. Araştırma sonuçlarına göre kültürel mesafe alt boyutlarından “bireysellik” bağımlı değişken üzerinde anlamlı etkiye sahip iken; güç mesafesi, erkeklik/dişilik, belirsizlikten kaçınma, uzun dönemli uyum sağlama ve hoşgörü/kısıtlama boyutlarının anlamlı etkiye sahip olmadığı görülmektedir. Bununla birlikte kurumsal mesafenin düzenleyici, normatif ve bilişsel alt boyutlarının bağımlı değişken üzerinde anlamlı etkiye sahip olduğu ve ihracat miktarının ülkelerin gelişmişlik düzeylerine göre farklılık gösterdiği tespit edilmektedir.
Dağcılık- Heyecan Arayışı ve Ölüm Kaygısı Üzerine Bir İnceleme
Authors: GÜRER Burak
Published: May 2022

Dağcılık yapılış biçimine göre yüksek seviyede heyecan ve ölüm kaygısı içermektedir. Dağcılık sporunda var olan risk seviyesi heyecan arayışını ve ölüm kaygısını etkilemektedir. Araştırmada, dağcılık sporu yapanların heyecan arayışları ve yaşadıkları ölüm kaygısının incelenmesi amaçlanmıştır. Araştırmanın evrenini Türkiye’deki dağcılar, örneklemini ise rastgele örneklem yöntemi ile seçilmiş toplamda 516 (376 erkek, 140 kadın) sporcu oluşturmuştur. Veri toplama araçları olarak Sarıkaya (2013) tarafından geliştirilen Türkçe Ölüm Kaygısı ölçeği ile Hoyle vd., (2002) tarafından geliştirilen, Çelik ve Turan (2016) tarafından Türkçe’ ye uyarlanan Heyecan Arayışı ölçeği kullanılmıştır. Veriler online ve tırmanışlar sırasında yüz yüze toplanmıştır. Verilerin analizinde Independent Sample t test, Anova ve Korelasyon analizi kullanılmıştır. Sonuç olarak, dağcılar için heyecan arayışı ve ölüm kaygısı belirleyici bir unsur olarak ortaya çıkmıştır. Heyecan arayış düzeyleri ortalamanın üzerindedir. Genel olarak dağcılar düşük düzeyde ölüm kaygısı duymaktadır. Sadece kış tırmanışı yapanların ölüm kaygısı orta düzeydedir. Heyecan arayışı ile ölüm kaygısı arasında düşük seviyede pozitif ilişki saptanmıştır. Aşırı heyecan arayışı ve yüksek ölüm kaygısı tırmanış sırasında hata yapılmasına neden olabilir. Sporcuların özellikle kendi beceri, yetenek ve deneyimlerinin üstünde faaliyetler yapmaması önerilmektedir.
ORGANIZATION THE ACTIVITY OF ADMINISTRATIVE DEPARTMENTS OF THE ENTERPRISE
Authors:   Ivan Franko National University of Lviv, Kundytskyi Oleksandr , Kryveshko Olga ,   Ivan Franko National University of Lviv, Butyter Daniel ,   Uniwersytet Wroclawski, Poland, Shparyk Yarema ,   Ivan Franko National University of Lviv
Published: May 2022

In the article the essence of administrative departments of the enterprise is considered. Found that they have some differences compared to production (operational) departments. In general, the current interpretation of both administrative management and the nature of administrative departments in the West and in Ukraine are different. According to the researchs in modern management theory, a significant number of publications are devoted to the issues of building the organizational structure of enterprises and the formation of departments. However, most authors do not focus on the peculiarities of the organization of the administrative departments as the special units in enterprise. They are using the same principles to forming both administrative and operational departments. If we consider public administration, this issue is addressed in laws and regulations. If we analyze the activities of enterprises, there are no separate principles for organizing the activities of administrative and operational departments. Based on previous researchs, the features of administrative departments are characterized. The main differences between administrative and operational departments are identified. Based on the analysis of publications, the key principles of organizing the activities of administrative departments are identified. Classical principles are supplemented by such relevant ones as interchangeability, a variety of which is functional flexibility, rotation, flexibility and mobilization. Interchangeability of administrative staff is necessary to ensure the smooth operation of administrative units in the absence of staff in the workplace. The principles of flexibility and mobilization have become especially relevant in the context of the COVID-19 pandemic and martial law in Ukraine. Adherence to these principles makes it possible in part to ensure the functioning of the administrative apparatus of enterprises. Based on the analysis, it was concluded that the key principles of work organization for administrative and operational departments differ. It is emphasized that administrative processes are typical for auxiliary divisions of enterprises. Understanding their differences from the processes of production activities can ensure the effective operation of such departments.
Productivity Improvement: From a Multipurpose to a Single-Product Unit and from Batch to Continuous Production
Authors: Otto Eberhard
Published: May 2022

Ciba Specialty Chemicals has been manufacturing the Ciba® IRGAFOS® 168 Process Stabilizer for 25 years. Two fundamental changes in the design concept of the production equipment and in the process have been implemented:• Firstly from a multipurpose unit to a single-product unit, both running with a batch-wise manufacturing process.• Secondly from a batch-wise process to a continuous one, both running in dedicated single-product units. Remarkable improvements in productivity have been achieved over the years, due to the extension of know-how about the product itself and its manufacturing process and to revisions in the design concept of the equipment and the production strategy.
Plant 2000 – An Exercise in the Benchmarking of Multipurpose Chemical Manufacturing Plants in the Pharmaceutical Sector
Authors: Born Marco , Foley Paul , Fretz Robert , Miess Richard , Oxley Tim
Published: May 2022

A study was performed to compare the investment costs and functionality of a number of different multipurpose chemical manufacturing plants, all used for the manufacture of active pharmaceutical ingredients and their intermediates. In parallel the functionality required to process a
large number of steps was assessed and the results of the two studies were combined. A description of the methodology and of the key findings is given.
Automation d'une Installation Polyvalente
Authors: Semadeni Adolfo , Meyer Guy-Bernard
Published: May 2022

The characteristics of a multipurpose production unit are its capacity to carry out chemical processes for highly complex molecules with several synthesis steps and its high flexibility to ensure fast adaptation to different manufacturing procedures, thereby greatly reducing campaign change-over times. As for the technical aspects, the unit is designed in standard and independent modules, linked to each other by distribution stations and collector groups. To meet these flexibility and rapid change-over requirements and to reduce operating costs, the production unit is automated.The solutions chosen depend on the context of the projects. One of the main aspects of the industrial site of Monthey is the high level of automation of its equipment and the standardisation of its concepts and systems. For more than 20 years, a single type of process control system (FOCLAN) has been used on the site. Thus, coherent automation concepts are designed and passed on from project to project, encouraged by an uninterrupted development of the control system.The automation of a multipurpose facility differs in many points from that of a standard unit. To meet project requirements in terms of safety, flexibility and multivalence, automation design has evolved towards better use of the possibilities of the automation system, a larger modularity of the 'application' programmes and a strict separation between the description of the unit (mechanical) and that of the process (recipe).
From Maleic Anhydrides to Substituted Resorcinols
Authors: Abou-Hadeed Khaled
Published: May 2022

Symmetrically substituted maleic anhydrides react at -78 °C with lithiomethyl phenyl sulfone to give the corresponding 4-hydroxy-4-(phenylsulfonylmethyl)-buteno-4-lactones, which, on treatment with Mel/K2CO3 in acetone, are transformed into 5-methyl-5-phenylsulfonylcyclopent-2-ene-1,4-diones. These compounds rearrange in the presence of an excess of lithiomethyl phenyl sulfone at -78 °C and then butyllithium at -5 °C to ambient temperature into 4,5-disubstituted 6-methyl-2-phenylsulfonyl-resorcinols.
Chemistry at the Haute Ecole Valaisanne: Recent Developments in the Analytical Field
Authors: Frey Urban , Luisier Jean-Luc
Published: May 2022

The major activities of our competence centre 'Process engineering', which groups together the two fields of study, Chemistry and Food & Biotechnology, are applied research and development (aR&D) as well as technology transfer. Two years ago the analytical orientation of the Chemistry Department was reinforced in Sion.We would like to present two recent developments at our competence centre. The first one deals with a quality control method for wine corks which reduces the risk of altering the wine by the unwanted flavour of musty taint, commonly called 'cork taint'. The goal of this development was to set up a sensitive and selective analytical method at the ppt level for chloroanisoles that is sufficiently cheap and rapid for routine tests. The second item presented here is the development of an instrument for fast analysis of the global volatile contents (TV9000).
L’éducation comme valeur sociale complexe en langue et en discours, ou comment osciller entre fait et valeur
Authors: BELLACHHAB Abdelhadi
Published: May 2022

Situé dans la lignée de trois traditions : une inscrite en philosophie (méta)éthique, une deuxième en philosophie du langage et de l’esprit, et une troisième en sémantiques argumentatives, cet article tente d’argumenter en faveur d’une certaine épaisseur sémantique et conceptuelle du mot éducation, où description et valeur s’imbriquent dans un tout indissociable. En vertu de cette ontologie épaisse d’éducation, le mot implique du fait de sa signification même une propension à l’action, à l’origine de sa potentielle institutionnalisation.
La complexité des valeurs de la notion d’« ancienne colonie » dans la presse française
Authors: XIA Xiaoxiao
Published: May 2022

Dans une dénomination, la compréhension de la notion linguistique et les idées des sujets parlants construites spontanément peuvent se combiner. Cela engendre une complexité des valeurs sociales et des valeurs modales de la dénomination. « Ancienne colonie », dénomination utilisée par la presse française pour qualifier Hong Kong, a été choisie comme objet de la présente étude pour des raisons de croisement de points de vue (colonisateur – colonisé), et d’évolution temporelle (ancien – nouveau). Les principales interrogations portent sur le cinétisme sémantique argumentatif de la notion d’« ancienne colonie », ainsi que sur les diverses valeurs modales représentées dans cette dénomination. Il est constaté que le concept d’ancienne colonie présente de nombreux possibles argumentatifs qui reflètent l’idéologie des sujets parlants.
L’agentivité énonciative de la répétition dans la lettre de consultation médicale
Authors: Famy Aurore
Published: May 2022

L’étude soumise dans cet article a pour vocation d’identifier les caractéristiques formelles et les procédés sémiolinguistiques récurrents permettant la discursivisation de la pratique médicale de l’épileptologue. La lettre de consultation est plus qu’un document juridico-administratif clos mais bien une énonciation énoncée qui agit par la répétition. Par le truchement de la médiation discursive que constitue la lettre de consultation, des macro-actes de langage indirects construits permettent l’actualisation d’instaurations particulières. En utilisant une méthodologie de dépouillement manuel sur un corpus de lettres de consultation recueillies in situ, l’analyse de cet espace d’énonciation en tant que genre agentif, trivialement « où il se passe des choses », montre notamment que la répétition qui le caractérise, en tant que reprise d’énonciation, permet l’instauration ou la réfutation d’un diagnostic, la transmission de savoirs scientifiques, et surtout la construction d’un ethos médical spécialisé de l’auteur.
Diderot et les Antilles : nouvelle sensationnelle d’un tremblement de terre en 1770 dans son Voyage à Bourbonne et à Langres
Authors: Richard Odile
Published: May 2022

Dans le récit d’un voyage qu’il fait en terre natale, Voyage à Bourbonne et à Langres (1770), Diderot se prend à rêver, en commentant les origines souterraines du thermalisme local, aux dimensions gigantesques du globe terrestre, à ses interconnexions, et aux incidences potentielles d’un récent et mystérieux tremblement de terre aux Antilles sur notre continent européen. Ses intuitions scientifiques y sont aussi un poème à l’éloge de la Nature et une réflexion sur ses origines.
Changements socio-culturels et formes de sexuation dans la société « coutumière » boni de la Guyane française au tournant du XXe siècle
Authors: Moomou Jean
Published: May 2022

L’article propose une étude sur la manière dont les changements sociaux, économiques, politiques, voire culturels intervenus dans les dernières décennies du XXe siècle au sein de la société Boni ont contribué à modifier en profondeur les relations hommes/femmes, en particulier les pratiques et les représentations de la sexualité. À partir d’une méthodologie fondée sur l’enquête ethnographique, l’article tente de mettre en évidence les changements, mais aussi les continuités souterraines qui affectent les rapports sexués.
Un « dialogue » indiscipliné
Authors: Fontanille Jacques
Published: May 2022

Les disciplines scientifiques ne dialoguent pas, elles interagissent, et ces interactions peuvent prendre de très nombreuses formes. Cette contribution examine quelques-unes de ces formes d’interaction, sans prétendre à l’exhaustivité, et en prenant l’exemple des relations de la sémiotique avec l’anthropologie, la psychothérapie, la physique des matériaux, ainsi que d’une configuration transversale, celle de la transparence. Dans ces interactions, les précautions diplomatiques sont de première importance, et elles ne sont ni toujours réciproques, ni une garantie de succès ; mais toutes les situations sont riches d’enseignements : en matière d’interdisciplinarité, tout vaut mieux que la juxtaposition dans l’indifférence partagée.
Form’UL : un projet favorisant l’interdisciplinarité
Authors: Benos Céline , Macharinow Anne-Sophie
Published: May 2022

Form’UL est un projet dont l’objectif est d’améliorer la réussite pour les étudiants de premier cycle à l’Université de Limoges. Parmis les axes principaux du projet figure la transformation des maquettes de formation des licences générales en Approche Programme et Démarche par Compétences (APDC). L’interdisciplinarité est présente tout au long du projet Form’UL, de la création même du projet à la constitution de l’équipe d’accompagnement pédagogique pour l’APDC en passant par la méthodologie employée pour travailler à cette transformation des formations.
La VAE Collective
Authors: McLaughlin Cécile , Ragot Jean-François
Published: May 2022

Depuis 10 ans, l’IUT du Limousin a développé la VAE collective à travers un partenariat avec l’entreprise Orange sur la licence professionnelle Management de la Relation Client. Depuis, le processus s’est enrichi et a atteint une maturité suffisante pour que d’autres partenariats soient lancés sur cette licence et sur d’autres formations, contribuant ainsi au développement de la Formation Tout au Long de la Vie à l’université de Limoges.
Pandémie de COVID-19 : Les défis méthodologiques de la recherche sociétale actuelle
Authors: PELLETIER Petra , McLaughlin Cécile , Lefort Claire , BOESPFLUG Magali , ALAIN Sophie , FERRANDON Erwan
Published: May 2022

La complexité de la pandémie de COVID-19 révèle d’importants débats méthodologiques et des défis quant à l’articulation de différentes approches de recherche. La recherche sociétale actuelle concernant la COVID-19 met en évidence la nécessité d'une étude holistique de la situation de la pandémie de COVID-19, fondée sur une approche de recherche multidisciplinaire. L'approche multidisciplinaire apparaît indispensable pour saisir l'ennemi invisible qu’est le virus SARS-COV-2 et ses conséquences sociétales à « l’effet domino ». Dans cet article, nous proposons des pistes de réflexion concrètes qui s’appuient sur les approches méthodologiques de l’intelligence collective et de co-design. En effet, celles-ci permettent d’engager une logique de fertilisation croisée des disciplines en positionnant l’objet d’étude au centre des préoccupations de chacune des disciplines convoquées. C’est à partir de cette fertilisation croisée que le projet CoviZion pourra évoluer en passant d’un dispositif multidisciplinaire à un dispositif interdisciplinaire voire transdisciplinaire permettant une lecture à 360 degrés de la situation sociétale complexe et inédite qu’est la crise COVID-19. Cette approche transdisciplinaire est essentielle et connaît des implications importantes, notamment celle de fournir des outils permettant une meilleure efficacité dans la gestion des crises sanitaires par les politiques de santé publiques particulièrement.
Créer un langage végétal
Authors: REIDT Camille , PAYSANT Michel , PLAZANET Idelette , MARIONNET David , GLOAGUEN Vincent
Published: May 2022

La rencontre du chercheur et de l’artiste peut-elle conduire à la création d’un langage végétal ? A l’origine d’un dialogue interculturel entre chercheurs en sciences végétales et artistes plasticiens, ce questionnement a servi de fil conducteur à la définition d’une véritable dialectique végétale. Cet article propose une contribution tout à la fois expérimentale et méthodologique qui débouche sur la mise en oeuvre d’une recherche transdisciplinaire originale. Les pistes d’étude empruntées à cette occasion, tout comme les approches scientifiques et technologiques retenues pour sa mise en oeuvre, sont illustrées par le processus de création d’une œuvre majeure baptisée Essentia.
Goethe et l’interdisciplinarité active : l’os intermaxillaire
Authors: PONSOLLE Géraldine
Published: May 2022

Johann Wolfgang von Goethe, poète, scientifique et homme politique allemand (1749-1832) traversa le tournant des siècles avec un soucis constant d’harmonie et d’action. La nature profondément interdisciplinaire de son écriture dramatique comme de ses études scientifiques peut aider les chercheurs d’aujourd’hui à acquérir une vision différente de leurs pratiques interdisciplinaires. Quel est ce Goethe qui se passionne d’anatomie et recherche l’os intermaxillaire chez l’homme ? Quelles œuvres dramatiques reflètent ses analyses scientifiques ? Quelle méthode de recherche le mène à renverser un mythe des sciences du XVIIIème siècle et préfigure les avancées cruciales du XIXème siècle ? Entre personnages hybrides, morphogénèse et unité du vivant, Goethe semble bien proche des préoccupations de notre temps.
Les usages des tests non rédactionnels dans l’évaluation des connaissances à distance des étudiants de Pharmacie : impact du déploiement du e-learning lors de la crise sanitaire du COVID-19
Authors: NIKITOPOULOS Claire , PICARD Nicolas
Published: May 2022

L’implémentation de tests non rédactionnels entraîne de nouveaux usages dans l’évaluation des connaissances des étudiants. Cette recherche s’intéresse à l’évolution des tests non-rédactionnels et à l’impact du niveau de maitrise des enseignants sur Moodle dans le choix du format et du niveau de complexité des questions. Il ressort de notre étude que les formats de questions plus traditionnels restent les plus utilisés dans les évaluations formatives à distance. Cependant, la question cloze, plus récente et plus complexe dans sa mise en œuvre, a été fortement employée dans les évaluations de fin d’année afin d’obtenir un système de notation homogène entre les différentes disciplines. L’étude montre également que le choix des formats de questions employés dans les tests non rédactionnels est lié à d’autres facteurs que l’objectif pédagogique à atteindre.
A chemical catalyst enabling histone acylation with endogenous Acyl-CoA
Authors: Habazaki Misuzu , Mizumoto Shinsuke , Kajino Hidetoshi , Kujirai Tomoya , Kurumizaka Hitoshi , Kawashima Shigehiro , Yamatsugu Kenzo , Kanai Motomu
Published: May 2022

Post-translational modifications (PTMs) of proteins, e.g., epigenetic acetylation of lysine residues in histones, are crucial to cellular functions and related to diseases. Chemical tools to directly introducing epigenetic lysine acetylation hold promise for elucidating the PTM’s functions and treating diseases. Although several chemical catalysts introducing protein acetylation in live cells were reported, there is no precedent promoting in-cell acetylation of epigenetically important but often low-reactive histone proteins using endogenous acetyl-CoA, as histone acetyltransferases (HATs) do. Herein, we developed a chemical catalyst mBnA enabling selective in-cell histone lysine acylation (H2BK120ac) using endogenous acyl-CoA as a sole acyl donor. A hydroxamic acid of proper electronic characteristics as a nucleophilic catalytic site combined with a thiol-thioester exchange process enabled mBnA to activate low concentration of acyl-CoAs in cells, promoting histone lysine acylations (acetylation and malonylation). This chemical catalyst will be a small-molecule surrogate to HAT and thus a unique tool to synthetic epigenetics.
22nd Annual McGill Biomedical Graduate Conference (AMBGC)
Authors:   Experimental Medicine Graduate Students' Society (EMGSS)
Published: May 2022

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