bluuebunny/crossref_metadata_2025 huggingface dataset:
Degradation Behavior of Concrete after Freeze-Thaw Cycles and Then Exposure to High Temperatures
Authors: Xie Qifang , Yang Liujie , Hu Fangzheng , Hao Wenming , Yin Shenghua , Zhang Lipeng
Published: July 2019

Concrete behavior usually degrades due to freeze-thaw cycles, fire, or both. Existing studies on the degradation behavior of concrete due to exposure to high temperatures were primarily focused on unfrozen concrete. In this paper, the degradation behavior of damaged concrete, after different freeze-thaw cycles (25, 35, 45, and 55 cycles), exposure temperatures (20°C, 300°C, 400°C, and 500°C), and cooling methods (water-cooled and air-cooled), was tested with seventy-five prism specimens. The degradation behavior of the damaged concrete, such as surface characteristics, weight loss, compressive strength, peak strains, and elastic modulus, was studied and analyzed. Results show that (i) the surface color of the concrete does not change significantly throughout the test. As the number of freeze-thaw cycles and temperatures increase, the weight loss of the concrete specimens increases gradually. (ii) After freeze-thaw cycles, the relative strengths and elastic modulus of the concrete specimens significantly degrade compared with those of the unfrozen ones at same temperatures. (c) At elevated number of freeze-thaw cycles and exposure temperatures, the peak strain of the concrete increases gradually. (d) Cooling methods have different effects on the degradation of concrete under different number of freeze-thaw cycles. Finally, a uniaxial compression constitutive model for concrete after freeze-thaw cycles and then exposure to high temperatures was established and a good agreement was observed with test results.
Duplex TaqMan Hydrolysis Probe-Based Molecular Assay for Simultaneous Detection and Differentiation of Burkholderia pseudomallei and Leptospira spp. DNA
Authors: Mohd Ali Mohammad Ridhuan , Lih Huey Lee , Foo Phiaw Chong , Goay Yuan Xin , Ismail Asmaliza S. , Mustaffa Khairul Mohd Fadzli , Aziah Ismail , Kia Kien Phua , Harun Azian , Ismail Nabilah , Yean Yean Chan
Published: July 2019

Melioidosis and leptospirosis, caused by two different bacteria, Burkholderia pseudomallei and Leptospira spp., are potentially fatal infections that share a very similar spectrum of clinical features and cause significant mortality and morbidity in humans and livestock. Early detection is important for better clinical consequences. To our knowledge, there is no diagnostic tool available to simultaneously detect and differentiate melioidosis and leptospirosis in humans and animals. In this study, we described a duplex TaqMan probe-based qPCR for the detection of B. pseudomallei and Leptospira spp. DNA. The performance of the assay was evaluated on 20 B. pseudomallei isolates, 23 Leptospira strains, and 39 other microorganisms, as well as two sets of serially diluted reference strains. The duplex qPCR assay was able to detect 0.02 pg (~ 4 copies) Leptospira spp. DNA and 0.2 pg (~ 25.6 copies) B. pseudomallei DNA. No undesired amplification was observed in other microorganisms. In conclusion, the duplex qPCR assay was sensitive and specific for the detection of B. pseudomallei & Leptospira spp. DNA and is suitable for further analytical and clinical evaluation.
Early Alterations of Corneal Subbasal Plexus in Uncomplicated Type 1 Diabetes Patients
Authors: Schiano Lomoriello Domenico , Abicca Irene , Parravano Mariacristina , Giannini Daniela , Russo Benedetta , Frontoni Simona , Picconi Fabiana
Published: July 2019

Purpose. The purpose of our study is to describe the in vivo corneal confocal microscopy characteristics of subbasal nerve plexus in a highly selected population of patients affected by type 1 diabetes mellitus (T1DM) without any microvascular diabetes complications.Methods. We included 19 T1DM patients without diabetic peripheral neuropathy, diabetic autonomic neuropathy, diabetic retinopathy, and microalbuminuria. All patients underwent in vivo corneal confocal microscopy and blood analysis to determine subbasal nerve plexus parameters and their correlation with clinical data. We compared the results with 19 healthy controls.Results. The T1DM group showed a significant decrease of the nerve fiber length (P=0.032), the nerve fiber length density (P=0.034), the number of fibers (P=0.005), and the number of branchings (P=0.028), compared to healthy subjects. The nerve fiber length, nerve fiber length density, and number of fibers were directly related to the age at onset of diabetes and inversely to the duration of DM. BMI (body mass index) was highly related to the nerve fiber length (r = −0.6,P=0.007), to the nerve fiber length density (r = −0.6,P=0.007), and to the number of fibers (r = −0.587,P=0.008). No significant correlations were found between the corneal parameters and HbA1c.Conclusions. Early subclinical fiber corneal variation could be easily detected using in vivo corneal confocal microscopy, even in type 1 diabetes without any microvascular diabetes complications, including diabetic peripheral neuropathy, diabetic autonomic neuropathy, diabetic retinopathy, and microalbuminuria.
MYCRegulates theHIF2αStemness Pathway viaNanogandSox2to Maintain Self-Renewal in Cancer Stem Cells versus Non-Stem Cancer Cells
Authors: Das Bikul , Pal Bidisha , Bhuyan Rashmi , Li Hong , Sarma Anupam , Gayan Sukanya , Talukdar Joyeeta , Sandhya Sorra , Bhuyan Seema , Gogoi Gayatri , Gouw Arvin M. , Baishya Debabrat , Gotlib Jason R. , Kataki Amal C. , Felsher Dean W.
Published: July 2019

Cancer stem cells (CSC) maintain both undifferentiated self-renewing CSCs and differentiated, non-self-renewing non-CSCs through cellular division. However, molecular mechanisms that maintain self-renewal in CSCs versus non-CSCs are not yet clear. Here, we report that in a transgenic mouse model of MYC-induced T-cell leukemia, MYC, maintains self-renewal in Sca1+ CSCs versus Sca-1− non-CSCs. MYC preferentially bound to the promoter and activated hypoxia-inducible factor-2α (HIF2α) in Sca-1+ cells only. Furthermore, the reprogramming factors, Nanog and Sox2, facilitated MYC regulation of HIF2α in Sca-1+ versus Sca-1− cells. Reduced expression of HIF2α inhibited the self-renewal of Sca-1+ cells; this effect was blocked through suppression of ROS by N-acetyl cysteine or the knockdown of p53, Nanog, or Sox2. Similar results were seen in ABCG2+ CSCs versus ABCG2− non-CSCs from primary human T-cell lymphoma. Thus, MYC maintains self-renewal exclusively in CSCs by selectively binding to the promoter and activating the HIF2α stemness pathway. Identification of this stemness pathway as a unique CSC determinant may have significant therapeutic implications.

Significance:

These findings show that the HIF2α stemness pathway maintains leukemic stem cells downstream of MYC in human and mouse T-cell leukemias.
DNA-Dependent Protein Kinase Drives Prostate Cancer Progression through Transcriptional Regulation of the Wnt Signaling Pathway
Authors: Kothari Vishal , Goodwin Jonathan F. , Zhao Shuang G. , Drake Justin M. , Yin Yi , Chang S. Laura , Evans Joseph R. , Wilder-Romans Kari , Gabbara Kristina , Dylgjeri Emanuela , Chou Jonathan , Sun Grace , Tomlins Scott A. , Mehra Rohit , Hege Kristen , Filvaroff Ellen H. , Schaeffer Edward M. , Karnes R. Jeffrey , Quigley David A. , Rathkopf Dana E. , He Housheng H. , Speers Corey , Spratt Daniel E. , Gilbert Luke A. , Ashworth Alan , Chinnaiyan Arul M. , Raj Ganesh V. , Knudsen Karen E. , Feng Felix Y.
Published: July 2019

Purpose:

Protein kinases are known to play a prominent role in oncogenic progression across multiple cancer subtypes, yet their role in prostate cancer progression remains underexplored. The purpose of this study was to identify kinases that drive prostate cancer progression.

Experimental Design: To discover kinases that drive prostate cancer progression, we investigated the association between gene expression of all known kinases and long-term clinical outcomes in tumor samples from 545 patients with high-risk disease. We evaluated the impact of genetic and pharmacologic inhibition of the most significant kinase associated with metastatic progression in vitro and in vivo.

Results:

DNA-dependent protein kinase (DNAPK) was identified as the most significant kinase associated with metastatic progression in high-risk prostate cancer. Inhibition of DNAPK suppressed the growth of both AR-dependent and AR-independent prostate cancer cells. Gene set enrichment analysis nominated Wnt as the top pathway associated with DNAPK. We found that DNAPK interacts with the Wnt transcription factor LEF1 and is critical for LEF1-mediated transcription.

Conclusions:

Our data show that DNAPK drives prostate cancer progression through transcriptional regulation of Wnt signaling and is an attractive therapeutic target in aggressive prostate cancer.
Dual Antagonist of cIAP/XIAP ASTX660 Sensitizes HPV− and HPV+ Head and Neck Cancers to TNFα, TRAIL, and Radiation Therapy
Authors: Xiao Roy , An Yi , Ye Wenda , Derakhshan Adeeb , Cheng Hui , Yang Xinping , Allen Clint , Chen Zhong , Schmitt Nicole C. , Van Waes Carter
Published: July 2019

Purpose:

Human papillomavirus–negative (HPV−) head and neck squamous cell carcinomas (HNSCC) harbor frequent genomic amplification of Fas-associated death domain, with or without concurrent amplification of Baculovirus inhibitor of apoptosis repeat containing (BIRC2/3) genes encoding cellular inhibitor of apoptosis proteins 1/2 (cIAP1/2). Antagonists targeting cIAP1 have been reported to enhance sensitivity of HPV−, but not HPV+ tumors, to TNF family death ligands (TNF and TRAIL) and radiation.

Experimental Design: We tested a novel dual cIAP/XIAP antagonist ASTX660 in HPV+ and HPV− cell lines in combination with death ligands TNFα and TRAIL, and in preclinical xenograft models with radiation, an inducer of death ligands. The dependence of activity on TNF was examined by antibody depletion.

Results:

ASTX660 sensitized subsets of HPV− and HPV+ HNSCC cell lines to TNFα and TRAIL. These antitumor effects of ASTX660 are the result of both apoptosis and/or necroptosis among HPV− cells, and primarily by apoptosis (caspase 3 and caspase 8 cleavage) in HPV+ cells. ASTX660 enhanced restoration of protein expression and inhibitory activity of proapoptotic tumor suppressor TP53 in HPV+ HNSCC. Furthermore, ASTX660 combined with radiotherapy, an inducer of death ligands, significantly delayed growth of both HPV− and HPV+ human tumor xenografts, an effect attenuated by anti-TNFα pretreatment blockade.

Conclusions:

IAP1/XIAP antagonist, ASTX660, sensitizes HPV+ HNSCC to TNFα via a mechanism involving restoration of TP53. These findings serve to motivate further studies of dual cIAP/XIAP antagonists and future clinical trials combining these antagonists with radiotherapy to treat both HPV+ and HPV− HNSCC.
Photodynamic Therapy for the Treatment of Vertebral Metastases: A Phase I Clinical Trial
Authors: Fisher Carl , Ali Zakariya , Detsky Jay , Sahgal Arjun , David Elizabeth , Kunz Monica , Akens Margarete , Chow Edward , Whyne Cari , Burch Shane , Wilson Brian C. , Yee Albert
Published: July 2019

Purpose:

Vertebroplasty (VP) and balloon kyphoplasty (KP) are minimally invasive stabilization procedures for pathologic vertebral compression fractures (VCF). Concurrent administration of photodynamic therapy (PDT) as a tumor-ablative modality has yet to be studied in humans as a potential complement to improved mechanical stability that is afforded by vertebral cement augmentation (VCA).

Patients and Methods:

This first-in-human trial used a single 6 mg/m2 dose of the clinical photosensitizer Visudyne with escalating laser light doses. Following a cohort of light-only controls (n = 6), the drug and light treatment groups (n = 6 each) were 50, 100, 150, and 200 J/cm. VCA was performed within 15 minutes following PDT. Patients were clinically reviewed at 1 and 6 weeks. The primary outcome measure was safety from a neurologic perspective.

Results:

Thirty patients comprising a variety of primary tumors were treated with PDT and either KP or VP. Vertebral PDT was technically feasible and delivered in all study patients. No dose groups showed significant increases in pain as defined by the generic SF-36 as well as disease-specific EORTC-QLQ-BM22 and EORTC-QLQ-C15-PAL questionnaires. The 50 and 100 J/cm groups showed the most significant pain reduction (P < 0.05). Twelve (40%) patients experienced complications during the study including 3 patients with further vertebral fracture progression by 6 weeks despite VCA. No complications were directly attributed to PDT.

Conclusions:

Using the parameters described, vertebral PDT as an adjunct to VCA is safe from a pharmaceutical and neurologic perspective. The results of this trial motivate scale-up study evaluating potential PDT efficacy in vertebral metastatic treatment.
Ubiquitin-Specific Protease 3 Promotes Glioblastoma Cell Invasion and Epithelial–Mesenchymal Transition via Stabilizing Snail
Authors: Fan Ligang , Chen Zhengxin , Wu Xiaoting , Cai Xiaomin , Feng Shuang , Lu Jiacheng , Wang Huibo , Liu Ning
Published: July 2019

Epithelial–mesenchymal transition (EMT) represents one of the most important events in the invasion of glioblastomas (GBM); therefore, better understanding of mechanisms that govern EMT is crucial for the treatment of GBMs. In this study, we report that the deubiquitinase ubiquitin-specific protease 3 (USP3) is significantly upregulated in GBMs and correlates with a shorter median overall and relapse-free survival. Silencing of USP3 attenuates the migration and invasion abilities of GBM cells in vitro and tumor growth in an orthotopic xenograft mouse model. Mechanistically, we identify USP3 as a bona fide deubiquitinase for Snail, a master transcription factor that promotes EMT, in GBM cells. USP3 interacts directly with Snail and stabilizes Snail via deubiquitination. Ectopic expression of Snail could largely rescue the inhibitory effects of USP3 depletion on migration, invasion, and tumor growth of GBM cells. In addition, we found that USP3 strongly correlates with Snail expression in primary human GBM samples. Overall, our findings reveal a critical USP3–Snail signaling axis in EMT and invasion, and provide an effective therapeutic approach against GBM.

Implications:

Our study establishes USP3-mediated Snail stabilization as an important mechanism underlying GBM invasion and progression, and provides a rationale for potential therapeutic interventions in the treatment of GBM.
Recent Development in Three and Four Dimension Fetal Echocardiography
Authors: Chaoui Rabih , Abuhamad Alfred , Martins Juliana , Heling Kai Sven
Published: July 2019

Since its introduction >15 years ago, the use of spatial and temporal image correlation (STIC) technology has contributed substantially to fetal echocardiography. Moreover, significant advances have occurred in 3- and 4-dimensional (3D/4D) echocardiography over the past several years including the matrix probe along with advances in gray scale and color Doppler post processing, resulting in improved display of ultrasound images. In this article, we provide examples to show these recent developments including the use of color Doppler with STIC in the glass-body mode and the matrix probe thus enabling the demonstration of cardiac anomalies of the 4-chamber-view and great arteries. The use of the matrix probe allows the examination of cardiac structures in 2 orthogonal planes simultaneously, which can help in display of anatomy side by side (Biplane mode). In addition, the rapid image reconstruction of the matrix probe allows for the display of live 4D and the rapid acquisition of a STIC volume. The display of multiplanar images of the heart in 3D/4D has also been used to automate the display of ultrasound images, resulting in standardization of the image display and thus minimizing the operation dependency of the ultrasound examination. Future addition of image recognition software can also provide assistance in image review.
Effect of Vitamin D Supplementation on Lipid Profile in Vitamin D-Deficient Children with Type 1 Diabetes and Dyslipidemia
Authors: Hafez Mona , Musa Noha , Abdel Atty Sahar , Ibrahem Mohamed , Abdel Wahab Nehal
Published: July 2019

Background: Vitamin D (VD) was suggested to have both direct and indirect effects on modifying lipid profile in patients with diabetes through its regulatory action that increases the activity of lipoprotein lipase in adiposity. Objectives: To detect the relationship between serum 25-hydroxyvitamin D (25OHD) and lipid profiles in dyslipidemic T1D patients and study the effect of VD supplementation on lipid profiles of VD-deficient T1D patients. Methods: Fifty patients with T1D (for >2 years) and dyslipidemia were included. 25OHD was assessed and patients were divided accordingly into 2 groups: VD sufficiency (>30 ng/mL) and VD deficiency (VDD) or insufficiency (<29 ng/mL) who were allocated to VD3 supplementation for 4 months, then lipid profile was reevaluated in both groups. Results: Thirty patients had VDD, while 20 patients had VD sufficiency. There was no significant correlation between 25OHD and different study parameters (p > 0.05). A significant difference was found among both groups in the family history of coronary heart disease (p = 0.036) and free tetraiodothyronine 4 (p = 0.035). After 4 months of VD supplementation in VDD group, the mean difference (at 0 and 4 months) in low-density lipoproteins (LDL) and hemoglobin A1c (HbA1c) was statistically significant (p = 0.02 and 0.04 respectively) between both groups. The mean basal LDL was 126.91 mg/dL in VDD group that improved to 117.13 mg/dL after 4 months of VD therapy with a mean difference of –9.7 mg/dL compared to a mean difference of –2 mg/dL in VD sufficiency group. Conclusions: VDD was highly prevalent in patients with T1D. There was no significant correlation between 25OHD levels and lipid profile in patients with T1D. VD supplementation for 4 months had a significant lowering effect on LDL and HbA1c.
Pleural Effusion in Pulmonary and Extrapulmonary Blastomycosis
Authors: Yan Lei , Rohra Prih , Cheng Lin , Gattuso Paolo
Published: July 2019

Objective: Pleural effusion secondary to blastomycosis infection is an uncommon clinical manifestation of the disease. We undertook a retrospective study to assess the incidence and involvement of pleural effusion in patients with blastomycosis infection. Study Design: Institutional cytology and surgical pathology records were searched from December 1995 to October 2017 for cases of blastomycosis. The cytologic, surgical pathology, and clinical pertinent information was reviewed in detail. Results: A total of 77 cases of blastomycosis infection were recorded, with a male-to-female ratio of 1.7:1.0. Forty-eight cases of blastomycosis were pulmonary (62.3%), while 29 cases of blastomycosis were found in extrapulmonary sites (37.7%). The diagnosis of pulmonary blastomycosis was established by 24 lung biopsies/wedge resections, 22 bronchial alveolar lavages, and 2 lung fine needle aspirations. The 29 cases of extrapulmonary blastomycosis included 13 cases of bone (44.8%), 8 cases of skin (27.6%), 6 cases of soft tissue (20.7%), and 2 cases of brain infections (6.8%). Twenty-eight of 48 pulmonary cases were complicated by unilateral or bilateral pleural effusion (58.3%) detected by imaging studies. Four of the 28 pleural effusions were aspirated and examined by cytology. Two of the 4 pleural fluid cytologies showed involvement by blastomycosis (50%). In the extrapulmonary blastomycosis group, 9 of 29 patients showed unilateral or bilateral pleural effusions (31.0%), including 4 cases of bone, 4 cases of skin, and 1 case of brain involvement. Only 2 of the 9 pleural effusions were aspirated for cytology study. One of the 2 pleural fluid cytologies showed blastomycosis (50%). Conclusion: Pleural effusion detected by imaging is common in blastomycosis patients. Blastomycosis can involve pleural fluid in both pulmonary and extrapulmonary diseases. A broad infectious differential that includes blastomycosis should be considered to make a timely diagnosis and initiate antifungal therapy to prevent systemic infection and further dissemination of the disease.
Age-Related Modulations in Erythrocytes under Blood Bank Conditions
Authors: Hsieh Carl , Prabhu N.C. Srinivasa , Rajashekaraiah Vani
Published: July 2019

Background: During storage of erythrocytes, storage lesions are formed that reduce the safety and efficacy of the stored blood. Thus, there is a need to understand the changes that occur during storage. Most studies have focused on storage of a mixed population of erythrocytes. The aim of this study is to analyze the changes in young and old erythrocytes over the course if storage. Materials and Methods: Blood was collected from the blood bank at the Kempegowda Institute of Medical Sciences (KIMS) Hospital (Bengaluru, India) and stored for 35 days in CPDA-1 at 4°C. Every 5 days, erythrocytes were separated based on the blood’s age using a Percoll-BSA gradient. Young and old erythrocytes obtained were used for analysis of the following oxidative stress (OS) markers: hemoglobin (Hb), hemolysis, mechanical fragility, antioxidant enzymes (superoxide dismutase and catalase [CAT]), superoxides, sialic acid, glutamic oxaloacetate transaminase (GOT), glucose, plasma membrane redox system (PMRS), total antioxidant capacity-cupric ion reducing antioxidant capacity assay (TACCUPRAC), lactate dehydrogenase (LDH), lipid peroxidation products (malondialdehyde [MDA] and conjugate dienes), and protein oxidation products (advanced oxidation protein products and protein sulfhydryls). Result: Young cells had higher amounts of Hb, sialic acid, GOT, LDH, TACCUPRAC, CAT, and superoxides compared to old cells. Old cells, however, had higher PMRS and MDA levels with respect to young cells. Discussion: Young cells could endure OS during storage more efficiently than old cells. In conclusion, the efficacy of stored blood depends on the ratio of young cells in the population. This study highlights the prospects of storing young erythrocytes for a prolonged shelf life of blood.
STK33 Promotes the Growth and Progression of Human Pancreatic Neuroendocrine Tumour via Activation of the PI3K/AKT/mTOR Pathway
Authors: Zhou Bo , Xiang Jie , Zhan Canyang , Liu Jianhua , Yan Sheng
Published: July 2019

Background: Serine/threonine kinase 33 (STK33) has been reported to play an important role in cancer cell proliferation. We investigated the role of STK33 in pancreatic neuroendocrine tumour (PNET) and the underlying mechanisms. Methods: PNET specimens and adjacent non-tumorous pancreatic tissues from 84 patients who underwent curative surgery for PNET were stained by immunochemistry for STK33. The relationships among STK33 expression, clinicopathological parameters and clinical prognosis were statistically analysed. MTT, scratching, Transwell and apoptosis assays were employed to detect the effects of STK33 knockdown (siSTK33) or STK33 overexpression (pSTK33) on major oncogenic properties of cells of 2 PNET cell lines (BON and QGP-1), and real-time PCR and western blot were used to examine the expression of relevant genes. Results: Relative to its expression in normal pancreatic tissue, STK33 was overexpressed in PNET specimens. Furthermore, STK33 expression was significantly associated with World Health Organization classification (p < 0.001), American Joint Committee on Cancer stage (p < 0.001), lymph node metastasis (p < 0.001), tumour size (p = 0.022), sex (p = 0.003), perineural invasion (p < 0.001) and shorter disease-free survival of patients with PNET (p < 0.001). Enforced STK33 expression promoted PNET cell proliferation, migration and invasion and tumour growth and inhibited cell apoptosis, whereas STK33 depletion exerted the opposite effects. Mechanistic studies revealed that STK33 promoted growth and progression of PNET via activation of the phosphotidylinositol-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway. Conclusions: STK33 plays important roles in the tumour growth and progression of PNET via activation of the PI3K/AKT/mTOR pathway and has potential as a therapeutic target to improve PNET treatment.
Revision of Multiquaestia Karisch (Lepidoptera: Tortricidae: Grapholitini)
Authors: AARVIK LEIF , KARISCH TIMM
Published: July 2019

Eight species of Multiquaestia Karisch are described and illustrated. Two additional species known from single females are figured but not described. A key to the known species is given.
The pupal exuviae of Chironomus crassimanus Strenzke (Diptera: Chironomidae), an acid-resistant species from Germany
Authors: RODRIGUES GILBERTO GONÇALVES , LANGTON PETER H. , SCHARF BURKHARD W.
Published: July 2019

The first descriptions of the pupal exuviae of Chironomus crassimanus Strenzke, 1959 were based on mixed populations of Chironomus which did not allow a proper recognition of their features in the available taxonomical keys. This paper describes the morphological characteristics of Ch. crassimanus based on laboratory-reared specimens. A more comprehensive description is ensued and ecological information on the species is also provided.
New data on taxonomy of recent Prophalangopsidae (Orthoptera: Hagloidea)
Authors: LIU XIANWEI , ZHOU MIN , BI WENXUAN , TANG LIANG
Published: July 2019

Keys to subfamilies, genera and species of the Prophalangopsidae are provided. Two new species Aboiloilomimus guizhouensis sp. n. and Aboiloimimus ornatus sp. n. are described respectively from Guizhou and Sichuan of China. The female of Prophalangopsis obscura is found for the first time from Tibet and is given a diagnosis. All type specimens examined in this study are deposited in Shanghai Entomological Museum, CAS.
The enigmatic genus Ctenostylum Macquart with the description of a new species from the Brazilian Amazon Basin and a checklist of world Ctenostylidae species (Diptera)
Authors: RAFAEL JOSÉ ALBERTINO , DE JESUS PIMENTEL THEREZINHA , GODOI FABIO SIQUEIRA P. , MACHADO RENATO JOSE PIRES
Published: July 2019

The genus Ctenostylum Macquart, 1851 was known only from two male specimens, one from Brazil and one from Costa Rica. Ctenostylum fuscomaculatum n. sp., is described based in one female specimen collected in the Amazon Basin, the third specimen known. The diagnosis of the genus Ctenostylum is redefined and its relationships with other ctenostylid genera are discussed.
New data on soft corals (Cnidaria: Octocorallia: Alcyonacea) from Nha Trang Bay, South China Sea
Authors: DAUTOVA TATYANA N. , SAVINKIN OLEG V.
Published: July 2019

A new species of Eleutherobia is described, enlarging the Eleutherobia species group that lack sclerites in the anthocodiae. The Octocorallia of the South-China Sea are poorly known, and the data that is presented provides a new record of the genus for Vietnam. The original description of Sinularia manaarensis Verseveldt, 1980 was based on a single incomplete colony fragment collected in 1902 near Ceylon (Verseveldt, 1980, Pl. 16, Fig. 3). Here we present data on both living and preserved S. manaarensis colonies that were found in Nha Trang Bay (South China Sea) in 2006. The club-shaped surface sclerites with wide flattened handles are characteristic of the species. Images of live colonies are given along with a biogeographical discussion. S. arctium sp. nov., is also described. It has a remarkable assortment of sclerites, which includes both leptoclados- like clubs and warty clubs with a distinct central wart.
New species of Crotonia (Acari: Oribatida) from Tasmania Rainforest, and the habitat preferences of Crotoniidae
Authors: COLLOFF MATTHEW J.
Published: July 2019

Two new species of oribatid mite belonging to the genus Crotonia are described from tree trunks and their associated bryophytes in callidendrous rainforest, dominated by Nothofagus cunninghami, in Northeastern Tasmanian: C. tasmaniana sp. nov. and C. pyemaireneri sp. nov. Holonothrus ryszardi Łochyńska, 2008 is designated the junior subjective synonym of Crotonia ovata Olszanowski, 2000, and a supplementary description of the latter species is provided. The apparent arboreal habitat preferences of crotoniid mites are considered. In Tasmanian rainforest, the frequency of occurrence of these mites in moss on bark is higher than in terrestrial habitats, but not significantly so. High rainfall, a closed canopy, a low mean annual temperature and a consequent extensive corticolous and terricolous cover of bryophytes presents a continuum for these mites between ground and above-ground habitats.
First record of the genus Aristelliger (Squamata: Sphaerodactylidae) in Cuba, with the description of a new species
Authors: DÍAZ LUIS M. , HEDGES S. BLAIR
Published: July 2019

The genus Aristelliger comprises seven species of which six inhabit the West Indies, and one occurs in Central America and satellite islands. For the first time, the genus is reported from Cuba, and a new species (Aristelliger reyesi sp. n.) is described from that island. The new taxon has affinities with the smaller species of the genus (subgenus Aristelligella): A. expectatus, A. cochranae, and A. barbouri. It differs from them in color pattern and other morphological characters.
On two Jenynsia taxa (Cyprinodontiformes: Anablepidae) from Argentina, originally placed in the poeciliid genus Xiphophorus
Authors: KOERBER STEFAN , DE LAS MERCEDES AZPELICUETA MARÍA
Published: July 2019

The type material of Xiphophorus heckelii Weyenbergh, 1874 and X. obscurus Weyenbergh, 1877 has apparently been re-examined for the first time. Xiphophorus heckelii is confirmed as a junior synonym of Jenynsia multidentata (Jenyns, 1842). Xiphophorus obscurus is recognized as a senior synonym of Jenynsia pygogramma Boulenger, 1902, which is placed in synonymy. A lectotype and paralectotypes are designated for Jenynsia obscura (Weyenbergh, 1877).
Cuapetes Clark, 1919, a senior synonym of Kemponia Bruce, 2004 (Crustacea: Decapoda: Palaemonidae)
Authors: OKUNO JUNJI
Published: July 2019

Borradaile (1915) established Falciger Borradaile, 1915, as a subgenus of Periclimenes Costa, 1844, for nine species described by him as new to science: Periclimenes (Falciger) nilandensis Borradaile, 1915; P. (F.) affinis Borradaile, 1915; P. (F.) dubius Borradaile, 1915; P. (F.) compressus Borradaile, 1915; P. (F.) brocketti Borradaile, 1915; P. (F.) pottsi Borradaile, 1915; P. (F.) suvadivensis Borradaile, 1915; P. (F.) seychellensis Borradaile, 1915; and P. (F.) kolumadulensis Borradaile, 1915. Two years later, Borradaile (1917) increased the number of species in the subgenus up to 27, and designated Periclimenes petitthouarsi var. spinifera De Man, 1902, now considered to be Periclimenella spinifera (De Man, 1902), as the type species of the subgenus. Subsequently, Holthuis (1955) designated P. (F.) nilandensis as the type species because Periclimenes petitthouarsi var. spinifera was not included in the original description of Falciger by Borradaile (1915) (see ICZN 1999: Article 67.2). Earlier, Clark (1919) had proposed a replacement generic name Cuapetes Clark, 1919 for Borradaile’s Falciger, since the latter name is a junior homonym of Falciger Say, 1824 (Insecta: Coleoptera), Falciger Bucholz, 1869 (Arachnida: Arachnoidea), and Falciger Trouessart and Mégnin, 1883 (Arachnida: Arachnoidea) (see Holthuis 1993). Following current nomenclatorial rules, the type species of Cuapetes must thus be regarded to be P. (F.) nilandensis (see ICZN 1999: Article 67.8). Until now, shrimp taxonomists have always considered Cuapetes as a junior synonym of Periclimenes sensu lato (see Holthuis 1993; Chace and Bruce 1993), but a situation is herein corrected.
Tardigrades from Portugal: four new records and description of two new species
Authors: FONTOURA PAULO , PILATO GIOVANNI , LISI OSCAR , MORAIS PAULO
Published: July 2019

Six species of Eutardigrada are recorded from Portugal; four of them, Macrobiotus crenulatus Richters, 1904, Hypsibius seychellensis Pilato, Binda & Lisi, 2006, Diphascon (Diphascon) pingue (Marcus, 1936) and D. (Diphascon) patanei Binda & Pilato, 1971 are recorded for the first time in Portugal. Two species, Minibiotus orthofasciatus sp. nov. and Bertolanius (new name of Amphibolus) portucalensis sp. nov. are new to science. Minibiotus orthofasciatus sp. nov. is one of the species of the genus with three macroplacoids, microplacoid and cuticular pores forming transverse bands. The new species differs from all existing species by one or more of the following characters: distribution of the pores, shape of the pores, absence of dots on the legs, level of insertion of the stylet supports on the buccal tube. To the new species is attributed an unembryonated egg similar to those of Minibiotus intermedius (Plate, 1888), M. poricinctus Claxton, 1998, M. floriparus Claxton, 1998, and M. weglarskae Michalczyk, Kaczmarek & Claxton, 2005 but different from them in some details. Bertolanius portucalensis sp. nov. is very similar to the other species of the genus, but it differs from them in having very small cuticular tubercles. From some of them it differs by characters of the buccopharyngeal apparatus and/or of the eggs. This is the first record of the genus and of the Eohypsibiidae family in the Iberian Peninsula.
One new species of the Genus Scorpiops Peters, 1861 (Scorpiones: Euscorpiidae, Scorpiopinae) from Xizang, China
Authors: DI ZHI-YONG , ZHU MING-SHENG
Published: July 2019

Scorpiops lhasa sp. n., from China Xizang (Lhasa) is described. S. lhasa is small in size with respect to other species in the genus; external trichobothria on the patella number 17 (5 eb, 2 esb, 2 em, 4 est, 4 et) and ventral trichobothria on the patella number 10 (11 rarely); pedipalp fingers in both sexes are curved; chela narrow and elongated, the ratio between length and width is above 2.6.
A new crocodyliform from the Alcântara Formation (Cenomanian), Cajual Island, Brazil
Authors: KELLNER ALEXANDER W. A. , PINHEIRO ANDRÉ E. P. , AZEVEDO SERGIO A. K. , HENRIQUES DEISE D. R. , DE CARVALHO LUCIANA BARBOSA , OLIVEIRA GUSTAVO R.
Published: July 2019

A new mesoeucrocodylian (Crocodyliformes) is described from the Laje do Coringa site, earliest Late Cretaceous (early Cenomanian) of the São Luís Basin, northeastern Brazil. Due to the likely hetorodonty indicated by distinct alveoli shapes, Coringasuchus anisodontis gen. et sp. nov. is tentatively referred to the Notosuchia and distinguished from other members of this clade by the presence of obliquely implanted teeth with the main axis directed anterolingually-toposterolabially and the presence of alveoli that are distinctively raised above the level of the dorsal margin of the dentary. The material further confirms the interpretation that the fossil concentration of the Laje do Coringa site is the result of multiple reworking events from previous deposits, but the degree of time-averaging was possibly higher than previously suspected.
Erratum: CLAUDIO AUGUSTO R. DE SOUZA et al. (2008) On the Tityus stigmurus complex (Scorpiones, Buthidae).Zootaxa, 1987, 1–38.
Authors: AUGUSTO R. DE SOUZA CLAUDIO
Published: July 2019

(Erratum)
Erratum: Hodgson, C. et al. (2008) Phenacoccus solenopsis Tinsley (Sternorrhyncha: Coccoidea: Pseudococcidae),an invasive mealybug damaging cotton in Pakistan and India, with a discussion on seasonalmorphological variation. Zootaxa, 1913, 1–35.
Authors: HODGSON C.
Published: July 2019

(Erratum)
Integrative taxonomy identifies new (and old) species in the Lasioglossum (Dialictus) tegulare (Robertson) species group (Hymenoptera, Halictidae)
Authors: GIBBS JASON
Published: July 2019

An integrative taxonomic approach that utilizes the DNA barcode region of cytochrome c oxidase subunit 1 in conjunction with traditional morphological approaches identifies five distinct species previously recognized as Lasioglossum (Dialictus) tegulare (Robertson). Differences in DNA sequences and congruent, albeit minor, morphological variation support separation of L. tegulare into five species. Unique nucleotide substitution patterns for each species allows for character-based diagnostics using DNA barcodes. The names L. ellisiae (Sandhouse) and L. lepidii (Graenicher) are removed from synonymy. Two new species, L. puteulanum Gibbs sp. n. and L. carlinvillense Gibbs sp. n., are described. A key is provided, which permits the identification of both males and females. The utility of the DNA barcode region as part of an integrative taxonomic framework is discussed.
Discovery of a new Namurian archaeorthopterid from Ningxia, China (Insecta: Archaeorthoptera)
Authors: LIU YUSHUANG , REN DONG , PROKOP JAKUB
Published: July 2019

A new archaeorthopterid Chenxiella liuae gen, et sp. nov. is described from the Upper Carboniferous (Namurian B-C) of the Tupo Formation in Ningxia Hui Autonomous Region (China). The new taxon exhibits a unique combination of wing venation characters. Together with other described archaeorthopterids, this new specimen further demonstrated considerable diversity of this group in Namurian ecosystems. However, C. liuae gen. et sp. nov. (uncertain family assignment) makes the higher systematics and classification of Archaeorthoptera more complicated and difficult.
A new subfamily, genus, and species of Cephidae (Hymenoptera) from Australia
Authors: SMITH DAVID R. , SCHMIDT STEFAN
Published: July 2019

Australcephinae, n. subf., is described from Queensland, Australia, based on Australcephus storeyi, n. gen., n. sp. This is the only cephid known from Australia and one of the few from the Southern Hemisphere. A key is given for the three recognized subfamilies of Cephidae.
Revisions of Australian ground-hunting spiders: IV. The spider subfamily Diaprograptinae subfam. nov. (Araneomorphae: Miturgidae)
Authors: RAVEN ROBERT J.
Published: July 2019

The newly recognised Diaprograptinae includes the Australian Diaprograpta Simon, 1909, Eupograpta gen. nov., Mituliodon Raven & Stumkat, 2003, Mitzoruga gen. nov., Nuliodon gen. nov., and the New Zealand Zealoctenus Forster & Wilton, 1973. All genera are unique in the Miturgidae s. strict. in the possession of claw tufts, and more equivocally, in the apical segment of the posterior lateral spinnerets, which in Diaprograptinae is not as strongly elongated as in Miturga. Diaprograpta includes the type species, D. striola Simon, 1909 from Western Australia, D. hirsti sp. nov. from South Australia, D. alfredgodfreyi sp. nov. from Victoria, D. peterandrewsi sp. nov. from western Queensland and D. abrahamsae sp. nov. from southeast Queensland. Eupograpta includes E. kottae sp. nov., sympatric with Diaprograpta striola and E. anhat sp. nov., from western Queensland. Mitzoruga gen. nov. is described to accommodate Uliodon marmoreus (Hogg, 1896), M. insularis sp. nov., and M. elapines sp. nov., from xeric regions of Australia. The genus presents a character combination which challenges the boundary between the Miturgidae Simon, 1886 and Zoridae F. O. P.-Cambridge, 1893. Nuliodon gen. nov. includes only N. fishburni sp. nov. from eastern Australia.
First record of Hylomyscus walterverheyeni (Rodentia: Muridae) on the north-western side of the Sanaga River (western Cameroon)
Authors: MISSOUP ALAIN DIDIER , NICOLAS VIOLAINE , WENDELEN WIM , BILONG CHARLES FELIX BILONG , CRUAUD CORINNE , DENYS CHRISTIANE
Published: July 2019

We used both molecular and craniometrical data to test the presence of Hylomyscus walterverheyeni in the Cameroon Volcanic Line (CVL). Our molecular (cytochrome b and 16S gene sequencing) and morphometrical data (discriminant analyses) clearly show the presence of H. walterverheyeni in the CVL, north-west of the Sanaga River. Hylomyscus walterverheyeni occupies both lowland and mountain forests (up to 2000m asl). In our phylogenetic analyses, the CVL specimens form a monophyletic group. This clade seems to reflect the role of the Sanaga River as a barrier to gene flow within the species.
A new species of Monandrocarpa (Ascidiacea, Styelidae) from Vanuatu I. (South Pacific Ocean)
Authors: MONNIOT FRANÇOISE
Published: July 2019

The U.S  Coral Reef Research Foundation collected by SCUBA various marine invertebrates in the islands of Vanuatu. Among them was a small bulbous ascidian settled on thin test stolons of another discrete ascidian being very similar in colour and shape. It is a new species of the genus Monandrocarpa (Styelidae) in which few species have been recorded. This genus is characterised by gonads in rows of hermaphrodite polycarps, each of them containing a single male vesicle. Other species in the same genus are discussed.
Genetic characterization of the Aphyosemion calliurum species group and description of a new species from this assemblage: A. campomaanense (Cyprinodontiformes: Aplocheiloidei: Nothobranchiidae) from Southern Cameroon
Authors: AGNÈSE JEAN-FRANÇOIS , BRUMMETT RANDALL , CAMINADE PIERRE , CATALAN JOSETTE , KORNOBIS ETIENNE
Published: July 2019

The Aphyosemion calliurum species group is poorly diagnosed by chromatic and meristic characteristics leading various authors to propose different species as members. We used partial sequence of the mitochondrial cytochrome b gene to characterize all species that have been at one time or another included in the A. calliurum species group. Results obtained allowed a clear definition of the group which is composed of 10 species: A. ahli, A. australe, A. calliurum, A. celiae, A. edeanum, A. franzwerneri, A. heinemanni, A. lividum, A. pascheni, and a herein newly described species A. campomaanense. This new species is described from 26 specimens captured in small streams of the Campo-Ma’an region within the Ntem River basin of southern Cameroon. A. campomaanense n. sp. is distinguished from all the other species of the A. calliurum species group, and above all from A. ahli, by asymmetric coloration of the caudal fin with a yellow lower margin and a white upper margin, and a body with a dark blue background against which red spots are arrayed in horizontal rows towards the head merging into vertical rows posteriorly. This species is also genetically distinguished from the other species of the A. calliurum species group by its mitochondrial genome and its karyotype, characterized by an unusually high number of chromosomes and arms (2n= 44, NF=58).
Three new genera of Ptilomerinae (Hemiptera: Heteroptera: Gerridae) from Southeast Asia
Authors: ZETTEL H.
Published: July 2019

Celerobates gen. n. is erected and described to hold Rhyacobates imadatei Miyamoto, 1967 (type species). Celerobates imadatei (Miyamoto, 1967) comb. n. is probably endemic to Borneo, where it inhabits the torrents of large streams. Two further new genera are closely related with Ptilomera Amyot & Serville, 1843: Ptilomerella gen. n. is described from the southeast Asian mainland: Ptilomerella akekawati sp. n. (type species) is from southern Thailand (Surat Thani, PhangNga, Phuket); and Ptilomerella anderseni sp. n. is from Myanmar (Kayin State). Archaeoptilomera gen. n. is described from Borneo; Archaeoptilomera derlethi sp. n. (type species) is from East Kalimantan, Indonesia; and Archaeoptilomera kodadai sp. n. is from Sarawak, Malaysia.
Erythrocyte size as diagnostic character for the identification of live cryptic Odontophrynus americanus and O. cordobae (Anura: Cycloramphidae)
Authors: GRENAT P. , SALAS N. E. , MARTINO A. L.
Published: July 2019

External morphology and size do not allow a distinction between diploid Odontophrynus cordobae and tetraploid O. americanus (Beçak et al. 1967; Barrio and Pistol de Rubel 1972). In Córdoba province allopatric diploid populations are distributed to the NW and allopatric tetraploid populations to the SE. Sympatric populations would occur in the SW of the province. A diagnostic character should be found for a correct, simple and rapid distinction of the species without sacrificing individuals. Differences in erythrocyte size (ES) between diploid and tetraploid Odontophrynus were found (Rosset et al. 2006). Martino & Sinsch (2002) defined a range of erythrocyte area for O. cordobae and O. americanus but individuals were not cytogenetically studied. Rosset et al. (2006), showed cell areas from only 2 preserved museum specimens of O. cordobae.
A review of the African redflanked skinks of the Lygosoma fernandi (BURTON, 1836) species group (Squamata: Scincidae) and the role of climate change in their speciation
Authors: WAGNER PHILIPP , BÖHME WOLFGANG , PAUWELS OLIVIER S. G. , SCHMITZ ANDREAS
Published: July 2019

We present an analysis of the morphometric and genetic variability of Lygosoma fernandi. Geographical variation and taxonomic consequences are discussed and Lepidothyris Cope, 1892 is resurrected as genus for the L. fernandi species group. The results show that Lepidothyris fernandi sensu lato is a species complex, which comprises an eastern and a western species. Each of them has a further subspecies of its own, and a third distinct species is present in southwestern Central Africa. The morphological and genetic differences between these taxa are analyzed resulting in the description of two new taxa, and the resurrection of two more taxa.
Notes on chydorid endemism in continental Africa: Matralona gen. n., a monotypic Alonine from the Fouta Djalon Plateau (Guinea, West Africa) (Crustacea: Cladocera: Anomopoda)
Authors: VAN DAMME KAY , DUMONT HENRI J.
Published: July 2019

A study of the morphology of Alona simonei Dumont, 1981, here emended to Alona simoneae, from the ancient Fouta Djalon Plateau in Guinea (West Africa) reveals unique limb structures. We allocate this species to the monotypic Matralona gen. n. and consider it a relict of an Alona-like clade. Matralona gen. n. is another example of divergence in limb morphology among externally similar Aloninae. Separation of this monotypic genus is based on more than autapomorphies alone and we include arguments for significant isolation from the ancestral stock. Within the Aloninae, Matralona gen. n. shows closest affinities with the Australasian genus Armatalona Sinev, 2004. Both taxa may share a common ancestor. Matralona gen. n. is one of the most peculiar African Chydoridae with no close relatives on the continent. We discuss a few areas of endemism in Chydoridae that begin to emerge on continental Africa.
A new species of Rhopalorhynchus (Pycnogonida: Colossendeidae) from Lizard Island, North Queensland, Australia
Authors: STAPLES DAVID A.
Published: July 2019

A new species of pycnogonid of the genus Rhopalorhynchus Wood-Mason, 1873 is described from the shallow waters of Lizard Island, north Queensland, increasing the number of Rhopalorhynchus species from Queensland to three. One female and two males were collected from coral rubble sortings gathered by hand dredge. The new species is compared with its congeners and the status of R. gracillimus Carpenter, 1907 is reviewed. Variability in R. tenuissimus (Haswell, 1884) is recorded.
New species of Odontepyris Kieffer (Hymenoptera: Bethylidae), an ectoparasitoid of Telorta divergens (Butler) (Lepidoptera: Noctuidae) larvae
Authors: LIM JONGOK , SHIN SANGCHUL , LEE SEUNGHWAN
Published: July 2019

Odontepyris telortis sp. nov., an ectoparasitoid of the caterpillar of Telorta divergens (Butler) (Lepidoptera: Noctuidae) is described and illustrated, based on twelve female specimens collected from Korea. After revising all known species, a key for the species of the genus Odontepyris is presented for the Eastern Palaearctic region.
A new species of Thraulodes (Ephemeroptera: Leptophlebiidae, Atalophlebiinae) from a highly altered river in western Ecuador
Authors: FLOWERS R. WILLS
Published: July 2019

Thraulodes quevedoensis new species (type locality: Quevedo, Ecuador) is described from adults and nymphs. This species was found in a moderately polluted river running through a highly altered agricultural and urban landscape of western Ecuador.
First record of the genus Euchariomyia Bigot, 1888 from China (Diptera: Bombyliidae)
Authors: YAO GANG , YANG DING , EVENHUIS NEAL L.
Published: July 2019

The genus Euchariomyia Bigot is a small Oriental genus with three known species. It is recorded from China for the first time with one known species. Male and female genitalia of the species Euchariomyia dives Bigot are described. A key to the genera of Bombyliinae from China is presented.