bluuebunny/crossref_metadata_2025 huggingface dataset:
Designing Problem-Based Learning With a Flipped Classroom Design in Appreciating Fiction Prose
Authors: Jasril Jasril , Sunendar Dadang , Sumiyadi Sumiyadi , Mulyati Yeti
Published: March 2024

The appreciation of fictional prose can be used to shape the ethics and morals of students. Various approaches and learning models have been developed to help sharpen students' skills in appreciating fictional prose, although satisfactory results have not been achieved overall. Therefore, the aim of this research is to design a learning concept that has the potential to enhance students' capabilities in understanding and appreciating fictional prose. The research data is sourced from 12 articles obtained through Google Scholar, Sage Journals, Taylor and Francis, ProQuest, and Scopus databases. The articles used as data sources are related to the appreciation of fiction prose, flipped classrooms, and problem-based learning. Data collection and analysis were conducted using the read-note-analyze technique. The research findings affirm that a problem-based learning approach, combined with the implementation of a flipped classroom design, holds significant potential for improving students' appreciation skills of fictional prose and can be efficiently applied in the learning process. Furthermore, this model accommodates the use of technology in learning and facilitates group work among students.
PENATALAKSANAAN PEMBERIAN TEKNIK INHALASI AROMATERAPI LEMON CITRUS UNTUK MENURUNKAN INTENSITAS NYERI PERSALINAN KALA 1 FASE AKTIF
Authors: Ayuda Bella , Susilawati Sri , Nuryuniarti Rissa
Published: March 2024

Persalinan dan kelahiran adalah sebuah proses fisiologi yang menyertai kehidupan hampir setiap wanita. Walaupun proses persalinan fisiologis, tetapi pada umumnya menakutkan, karena disertai nyeri berat, bahkan terkadang menimbulkan kondisi fisik dan mental yang mengancam jiwa. Untuk mengurangi nyeri persalinan dapat dilakukan dengan metode nonfarmakologi yaitu pemberian aromaterapi. Aromaterapi yaitu terapi yang menggunakan essential oil atau sari minyak murni, zat yang terkandung dalam lemon salah satunya linalool berguna untuk menstabilkan system saraf sehingga dapat menimbulkan efek tenang bagi siapapun yang menghirupnya. Asuhan ini bertujuan untuk mengurangi nyeri persalinan kala 1 fase aktif. Metode yang dilakukan melakukan asuhan kebidanan dengan penatalaksanaan Teknik inhalasi yaitu ditetes 1-3 tetes ke kassa steril dihirup langsung selama 30 menit. Penilaian asuhan terhadap intensitas nyeri persalinan ini menggunakan Numeric Rating Scale (NRS) sebelum dan sesudah pemberian aromaterapi lemon citrus. Subjek dalam asuhan ini yaitu 5 orang ibu bersalin kala 1 fase aktif di PMB E. Waktu asuhan dilaksanakan pada bulan April-Mei tahun 2023 saat dilakukannya Praktek Klinik Kebidanan III (PKK III). Hasil asuhan terdapat pengaruh pemberian aromaterapi lemon citrus dengan rata-rata skornya 2,4 berkurang dari nyeri berat ke nyeri sedang. Kesimpulan pemberian aromaterapi lemon citrus efektif untuk mengurangi intensitas nyeri persalinan kala I fase aktif.
Virtual Real Estate: New Trend or Global Scam?
Authors: Chyhryna N. I. , Pankov D. A.
Published: March 2024

The paper studies the concept of «virtual real estate», the market of which is developing against the backdrop of the emergence of metaverses. The current trend in the development of the Internet involves the merging of gaming and social life, which forms a huge, rapidly growing economy of consumption of virtual goods. The main factor in adjusting the trend of digital development is the evolution of the interaction between the Internet and users, therefore, the article initially considered the features and distinctive features of web 1.0, web 2.0, web 3.0. The technical solutions that distinguish web 3.0 are shown, contributing to the expansion of opportunities for involving consumers in the virtual world and the formation of their own virtual economy. Further, the concept of «metaverse» is investigated, key characteristics are highlighted. It has been established that the metaverse is a hybrid of the virtual and physical worlds, creating a space for communication, life and work. The metaverse market is growing, which makes it attractive to investors, one of the ways to invest for which is to purchase virtual land and real estate. Virtual real estate cannot be touched, but it has value, increases in price, which makes it an attractive investment. The purchase of virtual real estate is carried out for real money. Virtual real estate is a piece of land in a virtual space on which it is possible to build objects and participate in the game. The article is an opportunity to understand what virtual real estate is – another global scam or an attractive investment.
Machine Learning Model for Processing Aerospace Images of the Earthʼs Surface
Authors: Starovoitova T. F. , Starovoitov I. A.
Published: March 2024

The article presents the specifics of acquisition and processing aerospace images of the earth's surface in the context of their digitalization for creating accurate topographic maps and plans in digital and graphic formats. A data processing model has been developed based on the Python programming language and neural networks, the purpose of which is to improve the recognition of objects in aerospace images. The methodology for creating a machine learning model includes defining the goals and objectives of the model, selecting an appropriate learning algorithm (in this case, neural networks), collecting and preparing a data set, tuning the model, and testing on a test data set. The shortcomings of existing data processing algorithms are also discussed and an approach is presented to improve the efficiency of data processing and analysis.
Elisa Martins da Silveira
Authors: Scovino Felipe
Published: March 2024

O artigo investiga os primeiros anos de trabalho de Elisa Martins da Silveira (1912-2001). Sua produção, que naquela altura era identificada como arte “primitiva” ou “ingênua”, consegue em pouco tempo integrar o Grupo Frente (1954-1956), um dos primeiros compromissos estéticos vinculados a uma discussão sobre arte de vanguarda no país. O trabalho de Silveira foi rapidamente legitimado, institucionalizado e premiado. Mas, passados 68 anos da sua segunda premiação pela Bienal de São Paulo, quem conhece a obra de Silveira? Discutir o início de seu trabalho, quando estava envolvido na seara do que era moderno nos anos 1950, em um momento de profunda transformação institucional é uma chave deste artigo.
EFFICACY OF PLATELET-RICH PLASMA IN ANDROGENETIC ALOPECIA AND CORRELATION BETWEEN PLATELET COUNT IN PRP WITH CLINICAL AND TRICHOSCOPIC IMPROVEMENT.
Authors: Kaur Tejinder , Sharma Samira , Bagga Permeet Kaur
Published: March 2024

Background: Androgenetic alopecia (AGA) is the most common form of patterned hair loss in males. All the available treatment options have
limited clinical response. Platelet rich plasma (PRP) is one of the new promising treatment modalities in AGA and there is limited data correlating
platelet count in PRP with clinical as well as trichoscopic response.
Aims And Objectives:
1. To evaluate the efcacy of PRP in AGA.
2. To nd correlation between platelet count in PRP with clinical and trichoscopic response.
Materials And Methods: Thirty male patients of AGA were enrolled. Every patient was given 3 sittings of PRP once a month for 3 consecutive
months. Platelet count in PRP was done by improved Neubauer chamber at every sitting. Patients were followed up every 4 weekly for 24 weeks.
Assessment of patients was done using global photography and trichoscopically by calculating hair density, hair diameter and terminal: vellus hair
ratio (T:V ratio). Objective grading of response was done at 24 weeks. Patient satisfaction scores were calculated using visual analog scale (VAS) at
12 and 24 weeks. Statistically signicant improvement in mean hair density, hair diameter and T:V r Results: atio were seen with PRP. Patients with
mean platelet count of 12.84±2.35 lacs in PRP had better improvement in trichoscopic parameters compared to cases having platelet count in PRP
above or below this range. PRP therapy can be an effective therapy in the management of AGA and by Conclusion: means of proper centrifugation
technique, optimum platelet count in PRP can be obtained which enhances the treatment outcome.
RELIABILITY, FLOOR AND CEILING EFFECT OF THE SCHOOL READINESS INVENTORY FOR PRESCHOOLERS WITH AUTISM SPECTRUM DISORDER
Authors: Missal Sujata , Dwivedi Amitabh Kishor
Published: March 2024

Background: Assessment of school readiness skills is an important aspect among preschoolers with Autism Spectrum Disorder for inclusive
education. However, there is a lack of well-designed tools that are specically developed for this purpose. The aim of this study was to evaluate the
reliability, oor and ceiling effects of the School Readiness Inventory for Preschoolers with Autism Spectrum Disorder. (SRIPA). Methods:
Reliability of the tool was investigated through predened hypotheses and correlation statistics between the items in SRIPA (attention , memory,
cognition, maths, receptive skills, expressive skills, social emotional skills, gross motor , ne motor and self help skills ). Floor and ceiling effects
were analysed. The Cronbach's alpha if item deleted for the tool ranged from 0.90 to 0.98, which su Results: ggest that the tool demonstrated
excellent internal consistency. The overall test-retest intra-correlation coefcient (ICC) of the SRIPA tool was 0.71 (95% Condence Interval;
0.65, 0.80), standard error of the measurement (SEM) was 0.72. The MDC 95%, ranged from 0.23 (item # 55) to 5.13 (item # 15), the overall MDC
95% of the tool was 2.00. All the items were observed with standard error (SE) of ≤ 015. The attention and memory domain showed a satisfactory
ceiling and oor effect with 11.6 and 8.05 respectively This study provides evidence of excellent i Conclusion: nternal consistency, good inter rater
reliability of SRIPA, expected oor and ceiling effect, good data completeness and an ability to detect changes over time. The results indicate that
SRIPA measures unique aspects of school readiness.
CEREBRAL VENOUS SINUS THROMBOSIS IN CHILDREN - A SERIES OF SEVEN CASES
Authors: Saraswat Pawan , Barnawal Sandeep , Agarwal Aditi , Prasad Rajniti , Singh Ankur
Published: March 2024

Cerebral venous sinus thrombosis in children is associated with a high incidence of morbidity and mortality. Clinical features are non specic and
variable. We report seven children admitted in the pediatric neurology ward with a median age of 3 years. The presented symptoms were headache,
weakness and abnormal body movement. On examination they had fever, papilloedema, and seventh cranial nerve palsy. The most common
underlying conditions were sepsis followed by nephrotic syndrome and ear infection. All cases received low molecular weight heparin and
warfarin and improved in follow up.
ULTRASONOGRAPHIC MEASUREMENT OF INFERIOR VENA CAVA DIAMETER AND COLLAPSIBILITY INDEX TO PREDICT HYPOTENSION FOLLOWING INDUCTION OF GENERAL ANAESTHESIA
Authors: Dayal Deena , A Venugopal , R Bhagyalakshmi
Published: March 2024

Introduction: Hypotension is likely to occur following induction of general anesthesia which can be aggravated by various factors like the drugs
used for induction, pre-existing cardiac dysfunction due to various causes, preoperative mean arterial pressure, physical status, pulmonary function
and intravascular volume status of the patient before induction .Preoperatively assessing the intravascular volume status to detect any latent
hypovolemia and if found, its timely correction can prevent hypotension to a great extent. This study aims to assess the role of inferior vena cava (
IVC) diameter measurements in relation to respiration assessed just before surgery in predicting hypotension following induction of general
anesthesia. i. To assess the preoperative ultrasonographic measurement of IVC diameter during expi Objective: ration ii. To assess the IVC
diameter variation during respiratory cycle to derive the collapsibility index (CI) measured using ultrasound and to assess predictability of
hypotension after induction using CI. This was a prospective study including 65 patients of either Methods: sex belonging to ASA Physical status I
and II ,undergoing elective surgery under general anaesthesia in the Department of Anaesthesiology, Regional Cancer Centre Trivandrum. IVC
measurement was recorded preoperatively in the preoperative holding area and the diameter measured at end expiration was taken as the maximum
IVC diameter (IVC dmax). IVC collapsibility index (IVC CI) is the difference between maximum and minimum diameter divided by maximum
diameter expressed as percentage. Heart rate (HR), non invasive blood pressure (NIBP) , mean arterial blood pressure (MABP) was recorded every
2 minutes for rst 10 minutes following induction of anaesthesia. Signicant hypotension was dened as >20% decrease in MABP from baseline.
The performance of the IVC CI as a diagnostic tool for predicting hypotension dened as mean arterial pressure ≥ 20% drop from the baseline was
evaluated by ROC curve analysis. The relation between signicant hypotension and IVC-CI was evaluat Results: ed using ROC curve analysis. We
found the area under curve to be 0.892 and a cutoff of 0.40 (40% collapsibility) with 65 % sensitivity and 92 % specicity, positive predictive value
of 92 % and accuracy of 76.92%. Using 45 % as cut off value for collapsibility index to predict hypotension, showed 100 % specicity and
sensitivity of 50% with a positive predictive value of 100 % and accuracy of 70.7 % . Patients with Conclusion: an IVC collapsibility index of more
than 45%, as assessed by ultrasonography, are more likely to develop signicant hypotension after induction of general anaesthesia.
A COMPARATIVE STUDY BETWEEN EARLY VS LATE ENTERAL FEEDING IN POST OPERATIVE PATIENTS UNDERGOING ELECTIVE LAPAROTOMIES IN AGMC & GBP HOSPITAL
Authors: Tara Hano , Ghosh Sunil Kumar , Kumar Das Kishore , Murasing Nitin
Published: March 2024

Introduction: In recent times, there has been a surge in popularity and interest towards early enteral nutrition (EN). In terms of wound and
respiratory infections, hospital stays, and death, some argue that early enteral feeding produces better outcomes than delayed enteral feeding, and
vice versa. Early enteral nutrition refers to any oral intake—such as supplemented oral feeding or registered oral intake- as well as any type of tube
feeding—gastric, duodenal, or jejunal—that starts within 24 hours following surgery and has a caloric content. Aim: The study's objective is to
examine the effects of early and late enteral nutrition after surgery in patients undergoing open cholecystectomy at Agartala Government Medical
College's Department of General Surgery (AGMC). Materials and methods: One and a half years, or from January 2021 to June 2022, a
prospective longitudinal study on one hundred patients who underwent elective laparotomy (open cholecystectomy) at AGMC & GBP hospital
was carried out in the department of General Surgery at AGMC. Result: Patients in the early enteral nutrition group were 35.14 years old on
average, while those in the late enteral nutrition group were 36.84 years old on average. The ratio of female to male in the early enteral group is
13.33%, whereas in the late enteral group, it is 11.22%. In the early enteral nutrition group, feed tolerance was higher than in the late enteral
nutrition group, with 43/54 (79.6%) versus 35/46 (76.08%). On post-operative day 4, 75.9% of the late enteral feeding group and 69.5% of the early
enteral feeding group were released from the hospital. Normal peristaltic sounds were detected after two days following surgery in 90.19% of the
early enteral feeding group and 63.2% of the late enteral feeding group, which was considerably less than the early fed group. Conclusion:
According to a study, feeding early yields greater results than eating later.Patients accepted early feeding just as well, and it allows for a shorter
hospital stay, which lowers treatment costs. To further validate the study ndings, a bigger multi-centric investigation is necessary to show
statistically signicant variations in the outcomes.
A CLINICOPATHOLOGICAL STUDY OF PERFORATION PERITONITIS IN A TERTIARY CARE CENTRE
Authors: Sharma Govind , Dutt Sharma Dinesh , Mathur Anshul , Khandal Shivangi
Published: March 2024

Introduction: Peritonitis is dened as inammation of the serosal membrane that lines the abdominal cavity and the organs contained therein.
Peritonitis secondary to perforation of the gastrointestinal tract, a common occurrence in this country, requires emergency surgical intervention and
is associated with signicant morbidity and mortality rates. Diagnosis is made clinically and conrmed by the presence of pneumoperitoneum on
radiograph. Aims And Objectives: This research paper is intended to study clinicopathological prole & outcome of surgical management in
perforation peritonitis with respect to age and sex distribution, clinical presentations, investigations, various anatomical sites of perforation,
complications. A retrospective and prospective study was conducted on total of 100 patients who pre Methodology: sented with hollow viscus
perforation peritonitis over a period of January 2017 to September 2019 in Department of General Surgery of Mahatma Gandhi and Mathura Das
Mathur hospitals attached to Dr. Sampurnanand Medical College, Jodhpur. Data was collected with respect to following variables:- 1)Particulars of
the Case. 2) History of the patient3)Clinical examination of the patient4)LaboratoryInvestigations. 5)X- ray chest & Flat Plate abdomen 6)
Ultrasonography abdomen 7) Contrast Enhanced Computed Tomography of abdomen(if required) 8) Intraoperative nding for site of perforation
9) Etiology of perforation 9) Operative procedure carried out 10) Post operative complications. Per Conclusion: foration peritonitis is mostly seen
in males during 3 th 4 and decade of life & present with pain abdomen, vomiting and distension. History of fever is one of the most useful clinical
criteria to differentiate typhoid from other perforations. Peptic perforation is the most common cause followed by appendicular perforation. These
cases can be conrmed with X-ray at plate abdomen. Ultrasonography and CECT abdomen are done in selected cases. These cases are managed
surgically. Patients may develop complications in the post operative period in which wound and chest infection are the common complications
encountered. Septicaemia can occur in some patients which increases the mortality.
MC-Keyboard: A Practical Phase I Trial Design for Targeted Therapies and Immunotherapies Integrating Multiple-Grade Toxicities
Authors: Jiang Liyun , Yin Zhulin , Yan Fangrong , Yuan Ying
Published: March 2024

Introduction

In targeted therapies and immunotherapies, the occurrence of low-grade (e.g., grade 1–2) toxicities (LGT) is common, while dose-limiting toxicities (DLT) are relatively rare. As a result, conventional phase I trial designs, solely based on DLTs and disregarding milder toxicities, are problematic when evaluating these novel therapies. Methods: To address this issue, we propose a novel phase I design called a multiple-constraint keyboard (MC-Keyboard) that integrates multiple toxicity constraints, accounting for both DLT and LGT, for precise dose escalation and de-escalation, and identification of the maximum tolerated dose (MTD). As a model-assisted design, an important feature of MC-Keyboard is that its dose-escalation or de-escalation rule can be pretabulated and incorporated into the trial protocol before the initiation of the trial, greatly simplifying its implementation. Results: The simulation study showed that the MC-Keyboard had high accuracy in identifying the MTD and is safer than some existing designs. Conclusion: The MC-Keyboard provides a novel, simple, and safe approach to assessing safety and identifying the MTD for targeted therapies and immunotherapies.
Using a two circuit negative feedback in adaptive friction
clutches
Authors: Shishkarev M.P.
Published: March 2024

It is shown that the introduction of the concept of adaptive friction clutches of the dual negative feedback with time
sharing of the action of the circuits and shutting down one of the paths in the interval of values of the friction coeffi cient
allows to increase the rated torque while maintaining the accuracy of clutch operation. It is proved that the accuracy of
clutch operation is higher in the case where the value of the maximum torque under the action of the second feedback
loop is greater than the maximum torque under the action of the fi rst feedback loop, and minimum torques are the same.
The Influence of Human Resource Interactions on Loyalty with Patient Satisfaction as an Intervening Variable in Hospital X Surabaya
Authors: Minarni Wartiningsih
Published: March 2024

Background: In the hospital industry, human resources are the drivers of the organization to achieve goals. The interaction of hospital human resources with patients is one of the essential aspects of service to increase patient satisfaction and loyalty.

Objective: This study aimed to determine the effect of hospital human resource interactions on loyalty through patient satisfaction as an intervening variable.

Methods: This type of research is quantitative analytic with a cross sectional design. The sampling technique was 339 respondents using random sampling technique. The data obtained will be analyzed using SmartPLS software (v3.2.9).

Result: Interaction has a significant effect on patient loyalty directly (β=0.161 and p-value=0.015). Interaction also affects patient loyalty through intervening patient satisfaction variables (β=0.094 and p-value = 0.049).

Conclusion: This study concludes that interaction has more effect on patient loyalty directly than through the intervening variable of patient satisfaction.
Effect of mHealth based intervention on Maternal Knowledge and Practices of Child Care: A quasi-experimental study
Authors: Siswati Tri Siswati , Sitasari Almira , Paramashanti Bunga Astria , Tjaronosari Tjaronosari , Nurhidayat Nurhidayat , Wijanarka Agus , Waris Lukman
Published: March 2024

Background:Child malnutrition contributes to elevated rates of mortality and morbidity, profoundly affecting child welfare. Maternal childcare knowledge and practices play a pivotal role in addressing this issue.
Objective:This study aims to evaluate the impact of the mHealth App on maternal knowledge and practices in child care.
Method:A randomized controlled trial was conducted in Yogyakarta, Indonesia, from May to August 2022. Mother-child pairs were assigned to either the intervention (n=100) or control (n=100) groups. Data on maternal knowledge and practices were collected at baseline, follow-up 1, and follow-up 2. Maternal knowledge was assessed using a structured questionnaire covering child growth and development, while feeding practices were evaluated using a yes-no checklist. The analysis of maternal knowledge and practices involved mean difference, t-test, and general estimating equations in STATA-15.
Result:The results revealed a consistent increase in knowledge and practice scores between follow-ups 1 and 2. The mHealth application significantly enhanced maternal knowledge about child growth, development, and feeding at follow-up 2 compared to baseline, with improvements of 1.42 (CI 95% 1.34-1.89), 1.32 (CI 95% 1.22-1.72), and 1.45 (CI 95% 1.34-2.42), respectively. Additionally, growth and development monitoring practices increased by 0.80 (CI 95% 0.08-0.99) and 0.98 (CI 95% 0.21-0.99).
Conclusion:The mHealth application significantly enhances maternal knowledge and practices related to child growth, development, and feeding.
Key words: mHealth; maternal; knowledge; practices; children
Unraveling Potential Confounding Variables in the Association Between Maternal Malaria and Child Stunting in Papua: A Case-Control Study with Mantel-Haenszel Analysis
Authors: Felle Zeth , Sahiddin Muhamad
Published: March 2024

Background:Papua is a malaria-endemic region with Indonesia's highest annual parasite incidence. At the same time, stunting is a common child health problem in Papua. Malaria incidence in pregnant women is considered a risk factor for stunting in children. Thus, the identification of confounding factors in this relationship is necessary.
Objective:The study aimed to determine significant confounding factors in maternal malaria and child stunting and clarify the true association between these two conditions.
Methods: The study with a case-control design was conducted at 14 Puskesmas from May to September 2023. The sample size was 681 children, consisting of toddlers who were stunted and not stunted and were selected by probability sampling technique. Data collection used questionnaires and anthropometric measurements. Statistical analysis used Mantel-Haenszel chi-square with a cut-off point for changes in the estimated coefficient for determining confounding> 10%.
Results: The results showed that the crude Odds Ratio of the effect of malaria incidence during pregnancy on the incidence of stunting in children was 1.746 (95% CI 1,062-2,872). Stratification analysis showed the adjusted Odds Ratio value of child sex (1.78), low birth weight (1.652), basic immunization status (1.771), breastfeeding status (1.753), maternal age (1.732), occupation (1.828), ethnicity (1.722) and family income (1.764). There were no potential confounding variables in the association between malaria incidence in pregnant women and childhood stunting (change in coefficient estimate <10%).
Conclusions: Public health interventions aimed at preventing malaria during pregnancy can be used as a strategy to reduce the risk of childhood stunting.
Keywords:Malaria; pregnancy; stunting; confounding; Indonesia
The Potency of Typical Plants of Central Sulawesi Province to Prevent Iron Deficiency Anemia: Experimental Study
Authors: Mulia Sakti Putri , Hi. Amir Sene Ikhsan , Ramadhan Kadar
Published: March 2024

Background: Central Sulawesi falls within the Wallacea region, making it home to various endemic flora and fauna. One distinctive plant in Central Sulawesi is the Moringa tree. The Moringa tree, especially its leaves, was often used as a culinary ingredient known as sayurkelor in the traditional cuisine of the Kaili ethnic group in Central Sulawesi Province.
Objective: This research aimed to determine the effectiveness of moringa leaf extract in increasing hemoglobin levels and erythrocyte count.
Method: Twenty-four male Wistar rats strain (Rattusnorvegicus) 9−10 weeks old and 200−250 grams were divided into four groups (n=6), normal as a no treatment, negative control, ethanol extract, and positive control during the 15thday. Blood samples on the 15thday were administered to determine blood count.
Result: The resultsof this study showed differences in hemoglobin and erythrocyte levels in the four experimental groups.The significant difference in average hemoglobin levels between Group 2 and Group 3 with a P-value <0.05 (P value 0.00). The difference between Group 2 and Group 4 is significant with a P-value <0.05 (P value 0.00), and the difference between Group 3 and Group 4 is significant with a P-value <0.05 (P value 0.03). the significant difference in the average erythrocyte counts between Group 2 and Group 3 with a P-value <0.05 (P value 0.00). The difference between Group 2 and Group 4 is not significant with a P-value >0.05 (P value 0.07). The difference between Group 3 and Group 4 has a P-value >0.05 (P value 0.63).
Conclusion: The research results indicate that pregnant Wistar rats experienced hemodilution characterized by a decrease in hemoglobin and erythrocyte levels during pregnancy. However, after being given ethanol extract from moringa leaves, there was an increase in hemoglobin and erythrocyte levels.
Keywords: Extract; ethanol; moringa; oleifera; hemoglobin
¿Es la teoría de la mente una función ejecutiva?
Authors: Zambrano-Cruz Renato
Published: March 2024

Este texto presenta una reflexión teórica de la teoría de la mente (ToM) y su configuración en la adultez, así como un abordaje de las evidencias respecto a sus componentes, tanto en la infancia como en la adultez, lo que involucra pensar que la habilidad de inferir estados mentales de los demás se manifiesta de manera cualitativamente diferente en la infancia y en la adultez. Se presentan evidencias alrededor de las bases neurocientíficas de la ToM y se termina explorando diferentes enfoques teóricos, en particular el enfoque ejecutivo, que aborda la teoría de la mente como una función ejecutiva (FE). Se concluye indicando que la evidencia señala que si bien la FE es necesaria para la configuración de la ToM no es suficiente para un adecuado desempeño mentalista.
Secondary syphilis: An unusual cause of osteolytic lesion diagnosed by 99mTc-MDP SPECT and presenting features
Authors: Lu Xia , Xu Chifeng , Zhou Haizhong , Xiao Qin , He Huiying
Published: March 2024

Herein, we present the case of a 68-year-old woman complaining of pain of the right knee, which was initially misdiagnosed by plain radiography as fracture on inner right tibia plateau but was finally clarified as osteolytic lesion secondary to syphilis affecting the whole right knee. The final diagnosis was made based on the valuable findings from bone scanning, which allows for imaging of abnormalities with much larger extent, a scale that is out of the examination capacity of plain radiography. Bone scanning was employed in this case, coupled with the use of 99mTc-MDP, to assess abnormal bone metabolism at the whole right knee next to the tibia plateau. The imaging results illustrated the diverse features of bone involvement of secondary syphilis, including periostitis, osteolysis as well as osteomyelitis, occurring together or in isolation.
Blood glucose level affects iodine-123 labeled MIBG uptake in the lung
Authors: Lim Andreas , Suh Minseok , Cheon Gi Jeong
Published: March 2024

The aim of this study was to evaluate the correlation of blood glucose and the metaiodobenzylguanidine (MIBG) uptake in lung and compare the difference between the lung uptake of MIBG in diabetic and non-diabetic patients. Patients who underwent iodine-123 MIBG whole-body scan (WBS) in the Department of Nuclear Medicine Seoul National University Hospital between January 2014 and July 2022 were recruited and analyzed. Semi-quantitative analysis of the mean value of lung-to-mediastinum ratio (LMR) was performed. Correlation was analyzed with Pearson correlation test and mean difference was analyzed with independent t-test. There were 36 patients in diabetic group and 57 patients in non-diabetic group with mean age of 56 ± 14.1 and 52 ± 14.6 years, respectively. The mean 24-h LMRs in diabetic and non-diabetic groups were 1.38 ± 0.20 and 1.17 ± 0.14, respectively. Fasting glucose showed a mean value of 136 ± 37.7 and 96 ± 8.2 mg/dL, respectively. There was a significant positive correlation in diabetic (r = 0.397; P = 0.016) and non-diabetic groups (r = 0.579; P <0.001) with significant mean difference (0.21; P <0.001). In conclusion, lung uptake of MIBG is positively correlated with blood sugar level, with diabetic patients displaying higher lung uptake of MIBG compared with non-diabetic patients. In addition, higher lung uptake of MIBG is evident in patients with higher fasting glucose level and even in non-diabetic patients. Thus, in the situations where MIBG therapy is required, the radiation dose to the lungs must be carefully adjusted for patients with high blood sugar level.
Comprehensive analysis of myelosuppression of pediatric patients receiving radiotherapy
Authors: Sun Yijie , Liu Hongjia , Li Chenguang , Li Yubin , Xie Huamu , Zhang Yibao
Published: March 2024

Pediatric oncology management necessitates distinct strategies for radiotherapy due to the heightened sensitivity of pediatric bone marrow to radiation exposure compared to adults. Therefore, this study aimed to compare the risk of radiation-induced myelosuppression between pediatric and adult patients by analyzing the correlations between gender, age, active marrow distribution, and radiation-induced myelosuppression. The medical records of 49 pediatric patients aged <15 years were retrospectively analyzed. Subgroup analyses based on sex and age were conducted to compare this pediatric patient data with data from adult patients reported in the literature. The observed rate of radiation-induced myelosuppression in the pediatric group was 59.18%, which was approximately twice the rate for the adult group (34%) reported in literature. Notably, the rates of leukopenia and granulocytopenia were observed in 53% and 45% of patients suffering from radiation-induced myelosuppression, respectively, compared to rates of thrombocytopenia and hemoglobinopenia observed in only 10% of patients, indicating that white blood cells and granulocytes are more sensitive indicators of radiation-induced myelosuppression. Our findings revealed that pediatric patients receiving radiotherapy in the head-and-neck regions face a higher risk of radiation-induced myelosuppression than adult patients due to the changes in active bone marrow during childhood development. Therefore, careful consideration of radiation-induced myelosuppression is essential during protocol optimization for pediatric patients receiving radiotherapy outside the pelvic region.
The dawn of personalized multi-omics: Detecting disease before you know it
Authors: Mundt Madsen Filip
Published: March 2024

Recent advancements in omics techniques have enabled deep profiling of an individual’s molecular makeup. The wealth of data produced offers insights into genetic predispositions, early disease markers, and personalized treatment strategies. However, the full potential of omics data emerges when combined into longitudinal and personal multi-omics space. Another interesting venue is the inclusion of continuous monitoring of physiological parameters through wearable technology. Wearable health devices, including smartwatches and biosensors, provide real-time data on heart rate, oxygen saturation, sleep patterns, activity levels, and much more. By integrating with omics data, wearables offer a comprehensive view of an individual’s health, allowing for early detection of deviations from normalcy. This convergence allows for the prediction and prevention of diseases at the individual level and provides a powerful monitoring tool in clinical and drug developmental settings. This review explores the fusion of omics and wearable technology, envisioning their synergy as a catalyst for a transformative shift in modern healthcare. Their merging enables predictive and personalized medicine. As these technologies continue to evolve, their translation into routine clinical practice holds the promise of a healthier future for all. Provided herein is a step-by-step vision for how longitudinal personalized multi-omics, combined with wearable devices, will guide proactive healthcare and transform drug discovery in translational medicine.
Phenology characteristics and demographic structure of Aleppo pine in the Algerian mediterranean forest: The case study of El-Harhouria afforestation
Authors: Beldjazia Amina , Missaoui Khaled , Gawai Rahul , Kout Akram , Kanouni Malika Rached , Neghnagh Amel , Samai Ibtissem
Published: March 2024

The structural characteristics of tree populations and their spatial distribution is an essential indicator of forest health. A subjective sampling of the Aleppo pine (Pinus halepensis Mill) of El-Harhouria afforestation in Algeria made it possible to establish the characteristics of this plant formation. In this case, five plots of 900 m2 were subjected to the following dendrometric measurements: circumference, total elevation, slenderness coefficient, and density of trees. The diachronic measurement of the total photosynthesis (Normalized Difference Vegetation Index) was estimated with remote sensing methods based on Landsat images from 1986 to 2021. Data analysis showed that the average density of ligneous trees is 1,207 individuals per hectare including an average basal area of 41.95 m2/ha. The diameter and height structures of the wooded stands show a predominance of old individuals. In addition, NDVI values are correlated with the age of the trees, while low values were recorded in old trees.
Tahap Pemahaman Pelajar terhadap Istilah Baharu COVID-19: Kajian terhadap Universiti Awam di Malaysia
Authors: Saimon Aminnudin , Abdul Latif Nazatul Aineena , Abdul Rahim Nazihah , Mohd Yusoff Ainul Insyirah , Mohammad Nur Syazani Hanis
Published: March 2024

Pandemik COVID-19 yang melanda dunia pada ketika ini telah menyebabkan kewujudan istilah-istilah baharu khususnya istilah yang digunakan dalam penjenamaan COVID-19 kepada masyarakat. Kajian ini bertujuan untuk mengetahui penggunaan istilah-istilah baharu dalam COVID-19. Kajian ini merupakan kajian kuantitatif yang menggunakan kaedah tinjauan menggunakan satu soal selidik untuk mengenal pasti istilah-istilah baharu dalam COVID-19 dan mengkaji tahap pemahaman pelajar terhadap istilah dalam COVID-19. Seramai 200 orang pelajar daripada empat buah universiti awam telah dipilih dengan menggunakan persampelan rawak berstrata. Dapatan kajian mendapati bahawa pelajar UIAM mencatat jumlah pemahaman yang tinggi diikuti oleh UPSI, UKM dan UM. Daripada jumlah 3952, pelajar UIAM mencatat 1001 pemahaman terhadap istilah-istilah yang diberikan, diikuti oleh UPSI sebanyak 998, UKM 995 dan UM 958. Dapatan juga menunjukkan bahawa kebanyakan pelajar memahami istilah-istilah yang digunakan dalam COVID-19. Istilah R-Naught, Aktiviti Survelan dan Triaging merupakan istilah yang dominan tidak diketahui oleh pelajar dari keempat-empat buah universiti. Kebanyakan pelajar lebih gemar menggunakan istilah bahasa Inggeris berbanding istilah bahasa Melayu seperti mask, hand sanitizer, surveying activity dan sebagainya. Hasil kajian mendapati bahawa pemahaman pelajar dilihat amat baik mengenai istilah-istilah yang wujud semasa pandemik COVID-19.
Pengambilan Giliran dalam Sidang Media COVID-19 Kementerian Kesihatan Malaysia
Authors: Binti Sharif Shamin , Bin Abdul Wahab Mohd Khaidir , Binti Abdul Rauf Rozaida
Published: March 2024

Pengambilan giliran merupakan unit paling asas dalam sesebuah perbualan. Setiap perbualan mempunyai struktur interaksi yang tersendiri. Kajian ini akan mengenal pasti dan membincangkan mengenai pengambilan giliran dalam sidang media COVID-19 Kementerian Kesihatan Malaysia dengan memfokuskan kepada dua sidang media COVID-19 iaitu pada 17 April 2020 dan 24 Oktober 2020. Sidang media ini melibatkan dua sesi namun fokus kajian adalah pada sesi kedua di mana ia melibatkan proses tanya jawab antara pemeran iaitu pihak kerajaan dan pihak wartawan. Kajian kualitatif dimanfaatkan dalam kajian ini melalui analisis kandungan teks. Kaedah pengumpulan data bagi kajian ini ialah melalui muat turun data dan kemudiannya, ujaran tersebut ditranskripsi serta disimpan dalam bentuk teks bertulis. Perbincangan kajian pula mengaplikasikan teori Analisis Perbualan oleh Liddicoat (2011) yang telah menggariskan tiga peraturan iaitu penutur semasa memilih penutur berikutnya, pemilihan diri sendiri sebagai penutur berikutnya dan penutur semasa meneruskan perbualan. Dapatan kajian menunjukkan bahawa ketiga-tiga peraturan pengambilan giliran iaitu penutur semasa memilih penutur berikutnya, pemilihan diri sendiri sebagai penutur berikutnya dan penutur semasa meneruskan perbualan dipatuhi oleh pemeran dalam sidang media COVID-19 KKM. Dalam peraturan pengambilan giliran, penutur semasa memilih penutur berikutnya mendominasi peraturan lain. Di samping itu, penggunaan bahasa dalam konteks kesantunan berbahasa juga dititikberatkan oleh pemeran melalui pengambilan giliran pada sidang media ini. Oleh itu, kepatuhan pengambilan giliran dalam kalangan pemeran dapat memastikan keberkesanan penyampaian maklumat dalam sidang media COVID-19 di Malaysia.
Analysis of the dynamic response of a base isolated building during an earthquake with an intensity of 7 points on the MSK-64 scale
Authors: Giziatullin Ilnur R. , Bubis Alexander A. , Polyakov Vladimir S.
Published: March 2024

Introduction. The problem is considered and the relevance of studying the behavior of buildings and structures with seismic isolation systems using lead rubber bearing under real seismic impact, as well as assessing their technical condition after the earthquake, is emphasized. The experience of studying the behavior of base isolated buildings under real seismic impact abroad and in Russia is given.

Materials and methods. The dynamic parameters seismic isolation of a reinforced concrete building using lead rubber bearing are investigated. Registration of seismic vibrations of the building was performed by a stationary station for dynamic monitoring. The results of processing the records were obtained based on the interpretation of monitoring data, including harmonic analysis, determination of the power spectral density, as well as the application of wavelet transform methods.

Results. The results of dynamic monitoring of a base isolated building of a sea terminal located in Petropavlovsk-Kamchatsky city during an earthquake of 04/03/2023 with a magnitude of Mw =6.6 and an intensity at the site of the building equal to 7 points on the MSK-64 scale are presented. An analysis of the response and dynamic parameters of the building was performed, as well as a visual inspection of structures, as well as the building's seismic isolation systems.

Conclusions. Analysis of the dynamic monitoring results made it possible to identify the natural vibration frequencies of the building, as well as to trace their changes during seismic impact. The maximum displacements of the building indicate minor shear deformations of the lead rubber bearing corresponding to the zone of their elastic operation. Both the rigidity of lead rubber bearing and the dynamic parameters of the building (frequencies (periods) of natural vibrations and the logarithmic damping decrement of the building) change depending on the intensity of the seismic impact and the shear deformation of the bearings, respectively. After the earthquake, widespread cracks and peeling of the plaster wall were observed with partial exposure of the layer of insulating material in the zone of filling with elastic elements the gaps between the strapping beams of the seismic isolation system and the structures of the building partitions at the level of the seismic isolating layer, which did not affect the operational reliability of the building. The study presented in this article shows that with the help of dynamic monitoring of buildings and structures, one can get a more complete and detailed understanding of their dynamic behavior, identify damage in the structural system of a building, and detect their undesirable or specific reactions that could not be taken into account when designing.
Another Improved Three Term PRP-CG Method with Global Convergent Properties for Solving Unconstrained Optimization Problems
Authors: Kamfa Kamilu , Ibrahim Sulaiman , Waziri M Y , Abashar Abdelrahman
Published: March 2024

Recently, several  three-term conjugate gradient (CG) methods for solving unconstrained optimization problems have been proposed. Most of the methods centred on improving the convergence of the classical PRP-CG method while retaining its excellent numerical performance. Generally the PRP method is not convergent, because it failed to satisfy the sufficient descent property, especially, under modified Armijo line search or Wolfe line search method. In this paper, we propose an efficient three-term conjugate gradient method by utilizing the modified PRP formula which satisfies both the sufficient descent and the global convergence properties under the Wolfe line search. In particular, a new conjugate parameter is constructed. This parameter retains the numerator of PRP method and constructs an acceleration model in the denominator. The new denominator is designed to enhance the reduction in the number of iteration, CPU time as well as the convergence. Numerical results generated using various standard unconstrained optimization problem shows that the proposed method is promising and demonstrates a better numerical performance in comparison with other well-known CG methods.
A Projected Hybrid Conjugate Gradient Method for Solving Large-scale System of Nonlinear Equations
Authors: Sabi'u Jamilu , Gadu Abubakar M
Published: March 2024

In this article, a fully derivative-free projected hybrid conjugate gradient method for solving large-scale systems of nonlinear equations is proposed. The proposed method is the convex combination of FR and PRP conjugate gradient methods with the projection method. However, the global convergence of the given method is established under suitable conditions with nonmonotone line search. Numerical results show that the method is efficient for large-scale problems.
Histogram-Based Detection of Tomato Maturity: A Preliminary Study
Authors: Baharom Nur Amalina , Mohamad Fatma Susilawati , Abdul Manaf Azizah
Published: March 2024

Color is one of the most important features of images. Estimating the ripeness of fruits via color can be performed as it is the dominant feature in describing the information of image. However, each of color model has given different performance when used in experiment. This paper reports a preliminary study to identify the ripeness of tomato by extracting the color features and compute into Histogram based method. Histogram proposes the number of color intensities in ROI (Region of Interest) or a whole image to give more possibilities result. Histogram based techniques merely count the number or frequency of pixels in an image. The output value of color model will be used as an input to the classifier in future works. Similarity measures such as Euclidean distance, City Block, Manhattan distance or Histogram Intersection will be explored to calculate the image similarity rating.
Production of a Super-Increasing Sequence based on the Fibonaci Sequence
Authors: Merzoug Assia , Ali-Pacha Adda , Hadj-Said Naima , Ali-Pacha Hana
Published: March 2024

One shows that we can build a long recurring sequence super-increasing and use it in the cryptographic system based on the Knapsack problem, for example the Merkle-Hellman cipher. Thus, we reduce the size of the key with the same system safety. For this, we have modified the generalized Fibonacci sequence to produce of a super-increasing sequence. This modification was based essentially on the use of real coefficients in the main recursive equation. The result of this, it is the transformation of the public key of the Merkle-Hellman crypto system into a secret algorithm and, for an equivalent complexity.
A SECURE ONLINE VOTING SYSTEM USING FACE RECOGNITION TECHNOLOGY
Authors: Abd Hamid Nazirah , Appunair Citra Devi Nair , Abidin Ahmad Faisal Amri , Mohamed Mohamad Afendee , Abdul Kadir Mohd Fadzil , Mohd Satar Siti Dhalila
Published: March 2024

Each individual has the opportunity to choose the leaders by practicing their democratic right to vote. Therefore, the voting process is fundamental in determining everyone's destiny. The demand for online voting is growing, and most voters prefer online voting because it saves their time and energy. Therefore, an online voting method is highly valued in today's digital age. However, a lack of security and mechanism to verify and validate voters in the voting system may lead to illegitimate voting and unethical behavior. Thus, the voting issue remains a significant concern regarding safety and security. This project proposes a secure online voting system using face recognition, allowing validated users to cast a vote. The proposed online voting system uses a deep learning technique, a convolutional neural network, to verify and validate that the authorized users are voting. In conclusion, the proposed secure online voting system with biometric authentication able to verify and validate the authorized user with the accuracy rate of 90% for voting purposes and the system will be advantageous for users since it is convenient, reliable, energy-efficient, and time-saving.