bluuebunny/crossref_metadata_2025 huggingface dataset:
Financial crisis probability measurement model
Authors: Mshvidobadze T. I
Published: September 2023

Methods. The research used the method of analysis and synthesis – to clarify the nature of modern financial crises, the method of grouping – to determine the types of financial crises, general and specific – to differentiate between different types of financial crises, econometric methods – to quantify the level of systemic risk in the financial sector that leads to the financial crisis. Results. Excessive credit growth, the main cause of financial crises, is reflected in the insufficient capitalization of the financial sector. The paper briefly reviews the theoretical and empirical studies on the developments in these markets around the financial crisis. Market-based measures of systemic risk, such as SRISK, which stands for systemic risk, allow monitoring of how such vulnerabilities emerge and progress in real time. Novelty. This paper presents a quantitative assessment of the level of systemic risk in the financial sector that leads to a financial crisis. The model builds on the theory that deleveraging will have a price impact and the greater the magnitude of the deleveraging, the more dangerous the adjustment. In its most extreme case, the real economy has restricted access to credit as the financial sector experiences a fire sale, thus endogenously generating a financial crisis. Practical value. In an econometric framework, the relationship between SRISK and severity of financial crisis for different developed countries is given. The paper focuses on financial crises characterized by disruptions in credit supply, the lower tail of which may be related to various factors. A report on the probability of a financial crisis is provided in real-time from an indication of excessive credit growth. The study shows the important role of the cross-border external effect of financial noncapitalization.
Problems of the development of «green» banking in Ukraine
Authors: Krylova O. V , Zamkovyy O. I , Horiacha O. I , Fedorova O. H
Published: September 2023

Methods. General and specific research methods were used during the research. The basis of the study was the theoretical and scientific–methodical provisions of economic sciences, banking theory and the monetary system, as well as modern concepts of economic growth in the country, theoretical achievements of domestic and foreign scientists, dedicated to the problems of the «green» economy and its impact on economic growth. The method of generalization was used in determining the «green» economy and «green» financing, which are the main reasons for the emergence and development of «green» banking in the world and in Ukraine. The method of scientific abstraction, structural decomposition, indication and deduction was used in substantiating the theoretical foundations of «green» financing and «green» banking. The method of grouping and system analysis made it possible to reveal the features of «green» banking in Ukraine, the problems of its development, and the systematization of ways of further implementation in the period of the post– war formation of the economy of Ukraine. Results. The main features and problems of the functioning of the Ukrainian «green» banking system in the modern period have been determined. The special role played by the effective development of «green» financing in the sustainable economic development of the country has been established. The main banking instruments used in the global practice of «green» banking, as well as the experience of using them in the banking system of Ukraine, were studied. An assessment of the obstacles to the application of «green» banking and the use of «green» financial instruments in the context of financing sustainable development projects in Ukraine was carried out. The main ways of overcoming the negative impact of global crises have been determined, taking into account the international experience of banking activity. Novelty. In the study, the experience of the development of «green» banking in Ukraine was studied and possible ways of using «green» financing during the period of building the economy of sustainable development and the post– war recovery of the country were determined. Practical value. Ways of further effective implementation of «green» banking in terms of the program of sustainable development of Ukraine and the construction of sustainable banks are proposed
The relationship between the prevalence of dental space infections in Pediatric patient and parents’ awareness
Authors: Akhter Fatema , Afroz Mohammed Malik , Alamri Leena Abdullah , Alshami Asma Naeem , Haque Tahsinul , Abdelrahim Rawa Kamal
Published: September 2023

Background: The facial spaces in head and neck are the potential spaces between the various layers of fascia normally filled with loose connective tissue and bounded by anatomical barriers, usually of bone, muscle or facial layers.
Objective: To evaluate the level of knowledge and awareness about space infection among pediatric patients and their parents in Riyadh, KSA which can lead to seeking early help.
Results: A total of 102 children (56 girls, 46 boys; mean age from 2-12 years) visited Dar al Uloom hospital since January 2019. Most of the patients (51 cases) were children aged 6–9 years. It has been observed that majority of 10- 12 years old children noticed pain first (58.3%) followed by abscess drainage (25%) whereas, large number of 2-5 years old children noticed pain as the first option (66.7%) followed by swelling (26.7%). Further, a greater number of 6-9 years old children noticed pain (80.4%) followed by swelling (7.8%). These results suggest that the association of the first symptom observed by the child with different age groups was found to be significant.
Conclusion: In our study, the most common age group of pediatric patient infected with space infection was from 6-9 years, and the most common source of infection was caries. The level of education does not affect the awareness. It was observed that the symptoms of space infection were first noticed by the child, and it was due to the lack of early visits to the dentist. Hence, there is a need of increased awareness of the parents towards space infection and its potential risk.
Bangladesh Journal of Medical Science Vol. 22 No. 04 October’23 Page : 773-777
Abnormal uterine bleeding in women of reproductive age: PALM-COEIN causes
Authors: Fedosiuk Kateryna , Pakharenko Lyudmyla , Chayka Kirill , Basiuha Iryna , Kurtash Oleg
Published: September 2023

Objective: Abnormal uterine bleeding (AUB) is an often pathology in women of reproductive age.
Materials and methods. The retrospective analysis of 336 patients with AUB was performed between 2017-2020. We analyzed the social and demographic data, reproductive function, somatic diseases, type and causes of AUB.
Results. According to PALM-COEIN classification polyps were found in 13.39 % of patients, adenomyosis – 20.83 %, leiomyoma – 37.50 %, malignancy/hyperplasia – 14.29 %, ovulation disorders – 24.11 %, endometrial factor – 12.20 %, iatrogenic reason – 6.25 %.
Conclusion. PALM-causes dominate over COEINetiological factors in the development of AUB in women of reproductive age. But, there are some differences in the rate of causes according to the age period.
Bangladesh Journal of Medical Science Vol. 22 No. 04 October’23 Page : 809-814
Impact of the Covid-19 pandemic on the psychological health of patients in the province of Kenitra of Morocco
Authors: Dahou Badreddine , Abidli Zakaria , Fellaq Sara El , Rkhaila Amine , Chahboune Mohammed , Ziri Rabea , Ahami Ahmed Omar Touhami
Published: September 2023

Objectives: The objective of this work is to assess the psychological impact of Covid-19 through the study of all variables likely to influence the mental health of patients declared positive for Covid-19. This investigation aims to integrate a protocol of psychological therapeutic followup of patients, which is as essential as medical follow-up.
Methods: Analytical study of the psychological impact of Covid-19 on patients treated in a health center in the province of Kenitra of Morocco over a period of 6 months.
Results: The follow-up of patients declared positive for Covid-19, reveals that, although the majority have never had a psychological or psychiatric history, 38% have stress, 49% anxiety and 51% sleep disorders.
Conclusion: The study shows that the Covid-19 pandemic generates alongside the physical symptoms, a significant psychological impact on patients Characterized by anxiety, insomnia and post-traumatic stress. Therefore, care integrating the psychological follow-up of patients is necessary.
Bangladesh Journal of Medical Science Vol. 22 No. 04 October’23 Page : 895-901
The Use of Artificial Intelligence in Academic Publishing: Preliminary Remarks and Perspectives
Authors: Kharlamova Ganna
Published: September 2023

Artificial intelligence programs are constantly developing, becoming an increasingly powerful tool for solving various problems. First of all, attempts have been made to use artificial intelligence (AI) to generate new texts, but practice shows that the level of creativity exhibited by these programs is still insufficient for producing substantial articles. Of course, this will not prevent AI programs from developing text, including generation of not only dissimilar text, but capably accomplishing certain conceptual tasks. However, even today, it is possible to use AI programs to solve standard tasks in the preparation, editing, reviewing, processing, and publication of scientific texts. This article will provide an overview of the latest trends in the use of AI programs for academic publishing using examples of several scientific journals. We will look at different levels of AI and their impact on editorial work and review the potential of AI in complementing human input.
Next, we will consider the following stages of working with scientific texts in the editorial offices of scientific journals: author and article registration in the journal system; initial analysis of the article; choice of reviewers; article review; communication with the author regarding received reviews; publication decision; proofreading and publication of work; its registration in database systems.
In the conclusion, we summarise tips for editors on how to use AI.
The Concept of ‘Militant Democracy’ in the Context of Russia’s Armed Aggression Against Ukraine
Authors: Bakumov Oleksandr
Published: September 2023

Background: The fall of a dictatorship is accompanied by a period of democratic transit, which necessitates the use of special measures to protect a young and, thus far, unstable democracy. This model’s use began in practice after the Second World War in connection with the spread of the doctrine of "democracy capable of defending itself," also known as militant democracy (English) or Wehrhafte (Streitbare) Demokratie (German). The flagship here was the German science of constitutional law, which formed the tools for the creation of a new legal system accounting for the mistakes of the Weimar Republic. This experience is especially relevant for Ukraine, as since 2014, it has faced external armed aggression by revanchist forces that took power from the heir of the Soviet empire, Russia, in which a totalitarian regime was established and became a full-fledged aggressor state.
Methods: The following methods were used in the work to study the concept of militant democracy in the conditions of Russia's armed aggression against Ukraine. The system multi-structural method was utilized to discover the means of militant democracy in Ukraine (ban of political parties, lustration, etc.), as well as problems associated with the use of certain militant democracy means. The logical-legal method made it possible to identify the essence of the decisions of the constitutional, supreme, and other courts, the decisions of the European Court of Human Rights, in which the means of militant democracy were used or the legality of their use was assessed (legality, constitutionality, or compliance with the European Convention on Human Rights). The comparative method justified the implementation of different countries’ experience (primarily, European) in reforming the constitutional and legislative regulation of the militant democracy in Ukraine and the mechanisms required for further action.
Results and Conclusions: The work contains proposals for the constitutional and legislative improvement of the regulation of the means of militant democracy in Ukraine, which are based on the pre-existing experiences across the world and the use of already existing practices that have been successfully tested and achieved results.
Pemanfaatan Penggunaan Digital Marketing Pada Usaha Kelompok Pengrajin Ornamen Tempel Ukir Tanah Liat Di Desa Mayong Lor, Kabupaten Jepara, Jawa Tengah
Authors: Purwaningrum Jayanti Putri , Fajrie Nur , Supriyono Supriyono , Zahro Nafi’ Inayati , Sutono Sugoro Bhakti , Rachmawati Ratri
Published: September 2023

Era 5.0 memaksa pelaku bisnis pada seluruh sektor merubah sistem pemasaran produknya dari tradisional menjadi digital marketing. Padahal pada kenyataannya tidak semua pelaku bisnis memahami berbagai bentuk digital marketing. Tujuan kegiatan pengabdian ini adalah memberikan pelatihan dan pendampingan bagi kelompok pengrajin ornamen ukir tanah liat di Desa Mayong Lor, Kabupaten Jepara, Jawa Tengah tentang pemanfaatan media sosial dalam pemasaran. Metode yang dilakukan dalam kegiatan ini adalah ceramah, diskusi sekaligus praktek yang langsung dilakukan oleh kelompok pengrajin. Peserta kegiatan adalah dua puluh orang pengrajin yang rata-rata belum memahami bagaimana pemanfaatan digital marketing dalam pemasaran. Hasil dari kegiatan ini adalah peserta mendapatkan ilmu pengetahuan tentang berbagai digital marketing baik dari pengertian dan jenisnya. Selain itu, peserta juga dapat membuat konten dan caption persuasif untuk pemasaran.
Sosialisasi Pemahaman Pendidik Tentang Determinan Kurikulum dalam Keterlaksanaan Pembelajaran Efektif
Authors: Novitasari Anindita Trinura , Hermanto Didik , Septiana Aldila , Wijayanti R.A Rica , Faisal Bagus Imam
Published: September 2023

Prestasi belajar yang ideal harus didukung pemahaman pendidikan dalam menjalankan kurikulum sekolah supaya sesuai dengan tingkat kebutuhan usianya untuk setiap tingkatan pendidikan. Determinan kurikulum menjadi asas yang mendasar dalam penentuan kurikulum. Terdapat empat determinan yang perlu dipahami pendidik untuk keterlaksanaan pembelajaran efektif, diantaranya determinan filosofis, determinan psikologis, determinan sosiologis,   dan determinan hakekat pengetahuan. Masing-masing determinan kurikulum ini memiliki lingkup sasarsan dalam mematangkan kurikulum yang terbentuk pada setiap satuan pendidikan sebagai asas yang melandasi kurikulum. Tujuan pengabdian kepada masyarakat ini adalah peningkatan pemahaman pendidik terhadap determinan kurikulum untuk pelaksanaan pembelajaran efektif yang dapat memberikan wawasan yang lebih luas dan pemahaman yang lebih mendalam  kepada pendidik terhadap bagaimana semestinya proses pembelajaran. Metode pelaksanaan pengabdian masyarakat adalah teknik sosialisasi yang terdiri observasi dan perencanaan, tahap tindakan, dan tahap evaluasi. Pengabdian masyarakat ini dilakukan pada guru tingkat satuan pendidikan anak usia dini dengan jumlah pendidik sebanyak 6 guru. Hasil pengabdian kepada masyarakat menunjukan peningkatan pemahaman pendidik  untuk keterlaksanaan pembelajaran efektif sehingga menjadi media bagi pendidik untuk bertukar pikiran secara aktif interaktif    berkaitan dengan keterlaksanaan pembelajaran yang telah berjalan selama ini.
Terapi Komplementer Untuk Mengatasi Hipertensi
Authors: Putri Rona Sari Mahaji , Mazarina Hilda
Published: September 2023

Kejadian hipertensi pada lansia masih tinggi, disebabkan oleh banyak factor termasuk gaya hidup lansia yang kurang sehat. Berbagai terapi farmakologi dan nonfarmakologi dapat dilakukan untuk menurunkan tekanan darah lansia. Terapi komplementer merupakan bagian dari terapi nonfarmakologi yang cenderung aman untuk dijalankan di rumah secara mandiri, yakni berupa gerakan olahraga ringan. Terapi otot progresif secara teori terbukti mampu menurunkan tekanan darah lansia hipertensi. Kegiatan masyarakat ini telah dilakukan terhadap 30 orang lansia di Kelurahan Tlogomas Malang, yang dilaksanakan di rumah salah satu warga. Rangkaian kegiatan yang dilakukan antara lain pemeriksaan tekanan darah, pemberian promosi kesehatan terakit hipertensi dan berbagai terapi komplementer, pelatihan terapi otot progresif, serta evaluasi kegiatan. Tujuan dari kegiatan ini adalah lansia mengetahui dan memahami tentang hipertensi dan terapi komplementer, serta dapat mampu melakukan terapi otot progresif di rumah secara mandiri. Hasil kegiatan pengabdian ini yaitu lansia mengikuti rangkaian kegiatan dengan sangat antusias, yang ditunjukkan dengan banyak pertanyaan yang diajukan saat kegiatan berlangsung dan terapi otot progresif dapat dilakukan lansia dengan sangat baik.
Aktivitas Fisik Melalui Senam Lutut Lansia Untuk Pola Hidup Sehat Lansia
Authors: Putra Ranu Baskora Aji , Setiawan Ipang , Priyono Bambang , Junaidi Said , Lestari Yanesti , Mulyawati Isti
Published: September 2023

Aktifitas fisik lansia yang kurang yang mengakibatkan kekakuan otot dan sendi-sendi terutama lutut. Sebagian besar lansia mengeluh kesakitan pada sendi lutut dan sukar untuk meluruskan tungkai. Adapun metode untuk menyelesaikan permasalahan tersebut akan ditawarkan alternatif solusi yang terdiri dari 3 kegiatan  yaitu promosi sehat dan  senam lutut lansia, serta cek kesehatan bagi lansia yang diawasi oleh tenaga kesehatan. Kegiatan promosi diharapkan mampu mengatasi akar permasalahan yang dihadapi mitra yaitu sikap acuh lansia terhadap apa yang dikonsumsi serta kurangnya aktivitas fisik pada sebagian besar lansia. Hasil kegiatan senam lutut yang merupakan kegiatan untuk menyelesaikan permasalahan kurangnya aktivitas gerak yang menyebabkan kekakuan sendi melalui porsi latihan yang sesuai dan latihan kelenturan otot. Kegiatan pengecekan kesehatan merupakan upaya preventif untuk mengetahui kondisi kesehatan lansia sehingga dapat menjadi “alarm” bagi lansia untuk lebih waspada dan berhati-hati dalam menjaga pola hidupnya. Alternatif solusi yang ditawarkan sesuai dengan skema pengabdian yaitu peningkatan kualitas hidup dalam hal kesehatan masyarakat dan keolahragaan.
Edukasi Pemeliharaan Kambing BoerPE Berkonsep Green Economy melalui Implementasi Smart Kandang di Kelompok Tani Dian Santosa Sleman Yogyakarta
Authors: Kentjonowaty Inggit , Mardhotillah Ach. Bagus Adhiluhung , Puspitarini Oktavia Rahayu , Humaidah Nurul
Published: September 2023

Pasca pandemi Covid-19 saat ini, memaksa masyarakat berfikir kreatif dan inovatif dalam berbagai hal terutama pada segi usaha dan profesi. Salah satunya bidang peternakan kambing crossbreed BoerPE, yaitu hasil inseminasi buatan antara kambing jantan BoerPE dengan indukan PE. Peningkatan produktivitas kambing BoerPEPE tentunya perlu didukung dengan adanya teknologi tepat guna sederhana bagi peternak dalam proses pemeliharaannya. Edukasi ini bertujuan untuk meningkatkan pengetahuan dan keterampilan peternak yang tergabung dalam Kelompok Tani Dian Santosa, DIY dalam aspek pemeliharaan ternak kambing BoePE yang lebih praktis, higenis dan produktif melalui pemanfaatan teknologi smart kandang kambing yang secara sederhana agar peternak mudah menerapkannya agar terciptanya lingkungan kandang yang higenis dan berdampak pada peningkatan produktivitas kambing BoerPEPE. Metode yang digunakan dalam kegiatan ini adalah Penyuluhan, merekonstruksi kandang konvensional menjadi smart kandang dan Pelatihan berjenjang mendaur ulang limbah padat dan cair menjadi bioaktivator dan kohe. Hasil kegiatan ini adalah peternak menyambut baik adanya teknologi sederhana berupa smart kandang kambing. Hal ini dibuktikan dengan tingkat pemahaman peternak tentang konsep pemeliharaan dengan smart kandang, terciptanya ekosistem pemeliharaan yang lebih higenis dan bau limbah yang minim karena smart kandang dilengkapi dengan alat pemisah limbah sehingga limbah terkoleksi secara teratur dan cepat tanpa terkontaminasi oleh tanah. Peternak memiliki keterampilan dalam pembuatan bioaktivator dari limbah cair (urine) untuk digunakan sebagai penambah unsur hara tanah dan kesuburan tanaman serta terampil dalam pembuatan kohe (kotoran hewan) dan bioaktivator.
Program Pendidikan Kesehatan tentang Kenakalan Remaja dan Dampaknya terhadap Kesehatan Reproduksi Remaja Puteri
Authors: Ilmiah Widia
Published: September 2023

Masa remaja dikenal dengan istilah masa mencari identitas diri, identik dengan berbagai permasalahan sosial, salah satunya kenakalan remaja. Jumlah remaja Indonesia menunjukkan seperemat dari jumlah penduduk seluruhnya. Data kenakalan remaja di Indonesia tentang tawuran, penyalahgunaan narkoba remaja bekerja, pelajar, remaja putri berpacaran, berpacaran usia 15-17 tahun diantaranya telah melakukan seks bebas, pernikahan dini remaja puteri, kasus aborsi karena kehamilan tidak diinginkan dari tahun ke tahun meningkat, dan angka pernikahan dini di Jawa Timur dan Kabupaten Probolinggo masih tinggi. Permasalahan mitra yaitu kurangnya pengetahuan remaja puteri tentang kenakalan, sikap dan perilaku serta dampaknya terhadap kesehatan reproduksi. Tujuan melakukan pendidikan kesehatan kenakalan remaja dan dampaknya pada KRR. Metode pelaksanaan yaitu pengukuran pengetahuan, sikap, perilaku awal siswi, pemberian pendidikan kesehatan kenakalan remaja dan kesehatan reproduksi, evaluasi. Hasil kegiatan setelah diberikan pendidikan kesehatan menunjukkan peningkatan pengetahuan remaja, sikap, perilaku positif. Oleh karena itu, perlunya integrasi materi KRR ke dalam kurikulum dan terstandar nasional.
CPR Goes to School : Pelatihan Basic Life Support pada Guru dan Siswa SMA di Kota Ambon
Authors: Angkejaya Ony Wibriyono , Rahawarin Halidah , Syahroni Sam , Tamalsi Dylan , Astina
Published: September 2023

Dalam keadaan darurat, nyawa seseorang dalam bahaya, dan tindakan segera diperlukan untuk mencegah kemungkinan kematian. Henti jantung adalah salah satu keadaan darurat yang paling sering terjadi. Cardiopulmonary resuscitation (CPR) adalah prosedur yang digunakan pada pasien serangan jantung dengan tujuan menghidupkan kembali jantung dan sistem pernapasan. Di luar rumah sakit, serangan jantung cukup sering terjadi. Ini karena rata-rata orang tidak dapat memberikan pertolongan pertama. Oleh karena itu latihan basic life support (BLS) harus dilakukan untuk masyarakat umum, termasuk guru dan siswa SMA. Di Kota Ambon, kegiatan ini dilakukan di sejumlah SMA pada tanggal 27 Juli hingga 19 Agustus 2023. Untuk melaksanakan latihan ini, materi BLS akan disediakan, dan permainan peran akan dilakukan. Para peserta dalam kegiatan ini sangat terlibat dan bersemangat dalam mengikuti pelajaran dan kegiatan, sesuai dengan temuan kegiatan. Selain itu, keakraban peserta dengan BLS meningkat. Diantisipasi bahwa latihan BLS akan sering dilakukan untuk menurunkan mortalitas terkait serangan jantung.
Penerapan Sistem Informasi Kesehatan (Siketan) Berbasis Teknologi Digital Untuk Meningkatkan Keakuratan Laporan Bulanan Angka Penyakit Puskesmas Benteng
Authors: Susanti Heni , Ali Irsan Taufik , Prayuda Rendi , Hendrias Alief Rizki Zidhane , Afrian Fadilah , Yanti Evi
Published: September 2023

Tenaga Kesehatan yang ada di  Puskesmas Benteng selama ini membuat penulisan buku register rekam medis dan laporan bulanan (LB1)  secara manual  pada kertas, dan dimuat pada dokumen Microsoft Excel dan pengiriman laporan bulanan ke Dinas Kesehatan melalui email. Pembuatan LB1 dengan sistem manual membuat pekerjaan tenaga kesehatan membutuhkan waktu yang lama. Tim PKM menganalisis situasi mitra memerlukan teknologi dengan mengembangkan sistem informasi Kesehatan (Siketan) berbasis teknologi digital untuk meningkatkan keakuratan laporan bulanan angka penyakit di Puskesmas benteng. Tujuan dari Tim PKM adalah memberikan sosialiasasi terkait Sistem Informasi Kesehatan (Siketan) dan melakukan demonstrasi penggunaan sistem informasi Kesehatan kepada tenaga medis Puskesmas Benteng.  Metode yang digunakan dalam PKM adalah dengan cara persentase dan demontrasi Siketan kepada seluruh peserta yang merupkan tenaga medis Puskesmas Benteng. Pemberian Siketan terhadap UPT Puskesmas Benteng di sambut baik dengan harapan agar kedepan mampu memberikan kemudahan pada tenaga Kesehatan UPT Puskesmas Benteng dalam Menyusun Laporan bulanan (LB1).
Penerapan dan Pendampingan Penggunaan Aplikasi Kamus Bahan Bangunan Berbasis Qr Code Pada Toko Tunas Bangunan Tanggetada
Authors: Iin Johar Nur , Sumpala Andi Tenri
Published: September 2023

Geliat ekonomi kearah positif berpengaruh pada tingkat pembangunan infrastruktur  daerah maupun pembangunan rumah penduduk di Kabupaten Kolaka, Provinsi Sulawesi Tenggara. Toko Tunas Bangunan Tanggetada adalah sebuah toko yang menjual bahan bangunan dengan harga yang kompetitif dan menangani pemenuhan kebutuhan Perseroan Terbatas yang menerima tender dari perbaikan infrastruktur jalan, memiliki beraneka ragam bahan bangunan dengan jumlah yang besar. Hal ini berdampak pada kesulitan dalam mengingat harga jual setiap produk. Tujuan kegiatan pengabdian masyarakat  ini adalah membangun aplikasi kamus data bahan bangunan berbasis Qr Code dan melakukan pendampingan penggunaan aplikasi.  Kegiatan  ini dilakukan selama satu (1) bulan. Adapun tahapan PkM terdiri dari analisis kebutuhan pengguna, desain aplikasi, pembuatan, pengujian aplikasi, penerapan aplikasi dan pendampingan penggunaan kamus bahan bangunan pada pemilik dan kasir. Hasil dari kegiatan ini adalah Pemilik dan kasir Toko Tunas Bangunan sudah mampu menggunakan aplikasi kamus barang berbasis Qr Code dan pendampingan masih dilakukan dalam hal penambahan  data  bahan bangunan  dan maintenance aplikasi jika nantinya diperlukan.
PENGARUH STRES KERJA, DAN LINGKUNGAN KERJA TERHADAP KINERJA PERAWAT DENGAN KEPUASAN KERJA SEBAGAI VARIABEL MEDIASI PADA MASA PANDEMI COVID-19 (STUDI PADA RSUD DR. H. CHASAN BOESOIRIE TERNATE)
Authors: Tuahuns Vikram B , Soleman Marwan Man , Husen Zulaiha
Published: September 2023

bjectives: The objectives of this study were: (1) To determine the effect of work stress on the performance of nurses at RSUD Dr. H. Chasan Boesoirie Ternate; (2) To determine the effect of the work environment on performance; (3) To determine the effect of the work environment on job satisfaction; (4) To determine the effect of job stress on job satisfaction; (5) To determine the effect of job satisfaction on performance; (6) To determine the effect of work stress on nurse performance mediated by job satisfaction; and (7) to determine the effect of the work environment on nurse performance mediated by job satisfaction. The number of research samples was 83 nurses.Methodology: The test tool used is SmartPLS 3.0 as a statistical test tool.Findings: The second, third, fifth, and seventh hypotheses are accepted because the statistical t value is greater than t table, and the p value is smaller than alpha 0.05. While the first, fourth and sixth hypotheses were rejected because the p-value was greater than 0.05.Conclusion: The results of this study indicate that: (1) Job stress has no effect on the performance of nurses at RSUD Dr. H. Chasan Boesoirie Ternate; (2) work environment has a significant effect on performance; (3) work environment has a significant effect on job satisfaction; (4) Job stress has no effect on job satisfaction; (5) Job satisfaction affects performance; (6) Job stress has no effect on nurse performance mediated by job satisfaction; and (7) work environment influences nurse performance mediated by job satisfaction.
Experimental comparison of changes in relative survival and fitness-related traits of wild, farm, and hybrid Atlantic salmon Salmo salar in nature
Authors: San Román IC , Bradbury IR , Crowley SE , Duffy SJ , Islam SS , Fleming IA
Published: September 2023

Farming of Atlantic salmon Salmo salar has resulted in highly domesticated individuals, with notable genetic and phenotypic differences from their wild counterparts. Understanding how interbreeding with aquaculture escapees affects wild, often at-risk populations is increasingly essential to conservation efforts. Here, we used an experimental release of wild, farm, and reciprocal F1 hybrid fry at 3 sites in the Garnish River in Newfoundland, Canada, to evaluate family and cross-specific patterns of recapture/survival, size, sex ratio, and precocial male maturation over a 28 mo period. Trends in cross type recapture changed over the study period, with the highest recapture at 3 mo in parr with wild mothers and between 15 and 28 mo in aquaculture offspring. Size trends among crosses and sites remained consistent over the study duration, with pure farm and wild-mother hybrids being consistently larger than wild individuals and 1 site displaying elevated sizes in all crosses. Rates of parr maturation differed by sex and cross type, and family-based analysis indicated family representation and size also remained consistent through time. These results indicate there is a difference in vital rates such as survival and precocial maturation between farm and wild Atlantic salmon during the freshwater early life history period, and this difference can change significantly over time. As such, an improved understanding of genetic and ecological interactions which takes this ontogenetic variation into account is likely essential to fully understand how hybridization and introgression with farm escapees are affecting wild populations.
Stable isotope analysis of baleen from North Atlantic right whales Eubalaena glacialis reflects distribution shift to the Gulf of St. Lawrence
Authors: Forbes RA , Nakamoto BJ , Lysiak NS , Wimmer T , Hayden B
Published: September 2023

Seasonal migration of the Critically Endangered North Atlantic right whale Eubalaena glacialis along the eastern seaboard of North America has been well studied. Since 2010, however, right whales have shifted their summer foraging location from the Bay of Fundy to the Gulf of St. Lawrence. There is a need to better understand right whale distribution to manage anthropogenic activities and mitigate impacts on whales. Stable isotope ratios of baleen plates can provide details about migration and foraging behaviour of an individual over a period of several years. We interpreted δ13C and δ15N cycles, examined whether stable isotope ratios of baleen could detect the right whale distribution shift, and compared variation within and among individuals before and after 2010. δ13C and δ15N values were compared between 8 right whales that died between 1992 and 2005 (pre-2010) and 5 right whales that died in 2019 (post-2010). The correlation between δ13C and δ15N varied considerably between individuals, indicating no clear pattern of annual migration in δ13C among whales. We observed a change in both isotope ratios after 2010, whereby the post-2010 whales were enriched in 13C and 15N relative to the pre-2010 whales (mean ± SE: 0.5 ± 0.1 and 0.9 ± 0.2‰, respectively). The isotopic variance among and within whales did not change after 2010. These results suggest that a range shift observed in sighting data is also reflected in the isotope ratios of right whale baleen. Detecting shifts in right whale migration is essential for protecting this species, and stable isotope analyses may be useful in future conservation efforts.
Chronic exposure to cigarette smoke extract increases nicotine withdrawal symptoms in adult and adolescent male rats
Authors: Reynaga Daisy D. , Cano Michelle , Belluzzi James D. , Leslie Frances M.
Published: September 2023

The aim of the current study was to determine whether non-nicotine constituents of cigarette smoke contribute to nicotine dependence in adolescent and adult male Sprague Dawley rats. For 10 days animals were given three times daily intravenous injections of nicotine (1.5 mg/kg/day) or cigarette smoke extract (CSE) containing an equivalent dose of nicotine. Both spontaneous and mecamylamine-precipitated withdrawal were then measured. Chronic treatment with CSE induced significantly greater somatic and affective withdrawal signs than nicotine in both adolescents and adults. Mecamylamine-precipitated somatic signs were similar at both ages. In contrast, animals spontaneously withdrawn from chronic drug treatment exhibited significant age differences: whereas adolescents chronically treated with nicotine did not show somatic signs, those treated with CSE showed similar physical withdrawal to those of adults. Mecamylamine did not precipitate anxiety-like behavior at either age. However, both adolescents and adults showed significant anxiety in a light-dark box test 18 h after spontaneous withdrawal. Anxiety-like behavior was still evident in an open field test 1 month after termination of drug treatment, with adolescents showing significantly greater affective symptoms than adults. Our findings indicate that non-nicotine constituents of cigarette smoke do contribute to dependence in both adolescents and adults and emphasize the importance of including smoke constituents with nicotine in animal models of tobacco dependence.
Evaluation of yeast-based additives, as an alternative to ionophores, on rumen fermentation of ruminant diets using an in vitro gas production system
Authors: Cagliari Amanda Regina , Magnani Elaine , Rigon Fernanda , Loregian Kalista Eloisa , Casagrande Ana Claudia , Amâncio Bruna Roberta , Bueno da Silva Juliana , Lisboa Santos Veronica , Marcondes Marcos Inácio , Paula Eduardo Marostegan , Del Bianco Benedeti Pedro , Branco Renata Helena
Published: September 2023

Introduction

The study aimed to assess yeast-based additives' effects, as monensin alternatives, on rumen fermentation parameters, greenhouse gas emissions, and ruminal kinetics of ruminant diets using an in vitro system. Three experiments were conducted, each individually evaluating escalating levels of three yeast-based additives.

Methods

Three experiments were designed: Experiment 1 evaluated prebiotic blend 1—yeast culture [Saccharomyces cerevisiae (Scer)], beta-glucans, fructooligosaccharides, galactooligosaccharides, and mannanoligosaccharides; Experiment 2 investigated prebiotic blend 2—beta-glucan fractions and mannanoligosaccharides from Scer; Experiment 3 examined yeast cells—hydrolyzed, inactivated, and spray-dried yeast (Scer) cells. Uniform experimental design and procedures were employed across the three experiments. Each experiment had six treatments: monensin (Rumensin®, 25 mg/kg DM) as positive control, and yeast additive levels (0, 533, 1,067, 1,600, and 2,133 mg/kg on DM basis) added to ruminant diets (60% corn silage and 40% concentrate). An in vitro gas production (GP) system with 50 AnkomRF bottles assessed total GP (at 24 and 48 hours), kinetics, fermentation profiles, methane (CH4), and carbon dioxide (CO2) concentrations. Comparison with monensin utilized Dunnett’s test (5%). Yeast additive levels were analyzed for linear and quadratic responses.

Results

In Experiment 1, the 1,600 mg/kg yeast additive had lower concentrations of propionate, isobutyrate, valerate, and branched-chain volatile fatty acids (BCVFAs), and a higher acetate concentration and acetate-to-propionate ratio than monensin. In Experiment 2, the 1,600 mg/kg yeast additive led to lower total VFA and isovalerate concentrations than monensin. Additionally, compared to the 1,067 mg/kg yeast additive, monensin showed lower isovalerate concentration and higher NH3-N concentration. In Experiment 3, the 533 mg/kg yeast additive resulted in lower valerate and BCVFA concentrations, and higher CH4 and CO2 concentrations than monensin. Monensin had lower total VFA, butyrate, and acetate-to-propionate ratio, and higher propionate concentration compared to the 2,133 mg/kg yeast additive.

Discussion

Collectively, these findings suggest yeast-based additives could be monensin alternatives, enhancing animal nutrient utilization efficiency and contributing to improved livestock sustainability.
Segmental and transmural motion of the rat myocardium estimated using quantitative ultrasound with new strategies for infarct detection
Authors: Wang Yinong , Chen Wufan , Wang Qing
Published: September 2023

Introduction: The estimation of myocardial motion abnormalities has great potential for the early diagnosis of myocardial infarction (MI). This study aims to quantitatively analyze the segmental and transmural myocardial motion in MI rats by incorporating two novel strategies of algorithm parameter optimization and transmural motion index (TMI) calculation.

Methods: Twenty-one rats were randomly divided into three groups (n = 7 per group): sham, MI, and ischemia–reperfusion (IR) groups. Ultrasound radio-frequency (RF) signals were acquired from each rat heart at 1 day and 28 days after animal model establishment; thus, a total of six datasets were represented as Sham1, Sham28, MI1, MI28, IR1, and IR28. The systolic cumulative displacement was calculated using our previously proposed vectorized normalized cross-correlation (VNCC) method. A semiautomatic regional and layer-specific myocardium segmentation framework was proposed for transmural and segmental myocardial motion estimation. Two novel strategies were proposed: the displacement-compensated cross-correlation coefficient (DCCCC) for algorithm parameter optimization and the transmural motion index (TMI) for quantitative estimation of the cross-wall transmural motion gradient.

Results: The results showed that an overlap value of 80% used in VNCC guaranteed a more accurate displacement calculation. Compared to the Sham1 group, the systolic myocardial motion reductions were significantly detected (p < 0.05) in the middle anteroseptal (M-ANT-SEP), basal anteroseptal (B-ANT-SEP), apical lateral (A-LAT), middle inferolateral (M-INF-LAT), and basal inferolateral (B-INF-LAT) walls as well as a significant TMI drop (p < 0.05) in the M-ANT-SEP wall in the MI1 rats; significant motion reductions (p < 0.05) were also detected in the B-ANT-SEP and A-LAT walls in the IR1 group. The motion improvements (p < 0.05) were detected in the M-INF-LAT wall in the MI28 group and the apical septal (A-SEP) wall in the IR28 group compared to the MI1 and IR1 groups, respectively.

Discussion: Our results show that the MI-induced reductions and reperfusion-induced recovery in systolic myocardial contractility could be successfully evaluated using our method, and most post-MI myocardial segments could recover systolic function to various extents in the remodeling phase. In conclusion, the ultrasound-based quantitative estimation framework for estimating segmental and transmural motion of the myocardium proposed in our study has great potential for non-invasive, novel, and early MI detection.
Genetic characteristics, antimicrobial susceptibility, and virulence genes distribution of Campylobacter isolated from local dual-purpose chickens in central China
Authors: Xiao Jia , Cheng Yiluo , Zhang Wenting , Lu Qin , Guo Yunqing , Hu Qiao , Wen Guoyuan , Shao Huabin , Luo Qingping , Zhang Tengfei
Published: September 2023

Food-borne antibiotic-resistant Campylobacter poses a serious threat to public health. To understand the prevalence and genetic characteristics of Campylobacter in Chinese local dual-purpose (meat and eggs) chickens, the genomes of 30 Campylobacter isolates, including 13 C. jejuni and 17 C. coli from Jianghan-chickens in central China, were sequenced and tested for antibiotic susceptibility. The results showed that CC-354 and CC-828 were the dominant clonal complexes of C. jejuni and C. coli, respectively, and a phylogenetic analysis showed that three unclassified multilocus sequence types of C. coli were more closely genetically related to C. jejuni than to other C. coli in this study. Of the six antibiotics tested, the highest resistance rates were to ciprofloxacin and tetracycline (100%), followed by lincomycin (63.3%), erythromycin (30.0%), amikacin (26.7%), and cefotaxime (20.0%). The antibiotic resistance rate of C. coli was higher than that of C. jejuni. The GyrA T86I mutation and 15 acquired resistance genes were detected with whole-genome sequencing (WGS). Among those, the GyrA T86I mutation and tet(O) were most prevalent (both 96.7%), followed by the blaOXA-type gene (90.0%), ant(6)-Ia (26.7%), aac(6’)-aph(3’’) (23.3%), erm(B) (13.3%), and other genes (3.3%). The ciprofloxacin and tetracycline resistance phenotypes correlated strongly with the GyrA T86I mutation and tet(O)/tet(L), respectively, but for other antibiotics, the correlation between genes and resistance phenotypes were weak, indicating that there may be resistance mechanisms other than the resistance genes detected in this study. Virulence gene analysis showed that several genes related to adhesion, colonization, and invasion (including cadF, porA, ciaB, and jlpA) and cytolethal distending toxin (cdtABC) were only present in C. jejuni. Overall, this study extends our knowledge of the epidemiology and antibiotic resistance of Campylobacter in local Chinese dual-purpose chickens.
EfficientNet family U-Net models for deep learning semantic segmentation of kidney tumors on CT images
Authors: Abdelrahman Abubaker , Viriri Serestina
Published: September 2023

Introduction

Kidney tumors are common cancer in advanced age, and providing early detection is crucial. Medical imaging and deep learning methods are increasingly attractive for identifying and segmenting kidney tumors. Convolutional neural networks have successfully classified and segmented images, enabling clinicians to recognize and segment tumors effectively. CT scans of kidneys aid in tumor assessment and morphology study, using semantic segmentation techniques for pixel-level identification of kidney and surrounding anatomy. Accurate diagnostic procedures are crucial for early detection of kidney cancer.

Methods

This paper proposes an EfficientNet model for complex segmentation by linking the encoder stage EfficientNet with U-Net. This model represents a more successful system with improved encoder and decoder features. The Intersection over Union (IoU) metric quantifies model performance.

Results and Discussion

The EfficientNet models showed high IoU_Scores for background, kidney, and tumor segmentation, with mean IoU_Scores ranging from 0.976 for B0 to 0.980 for B4. B7 received the highest IoU_Score for segmenting kidneys, while B4 received the highest for segmenting tumors. The study utilizes the KiTS19 dataset for contrast-enhanced CT images. Using Semantic segmentation for EfficientNet Family U-Net Models, our method proved even more reliable and will aid doctors in accurate tumor detection and image classification for early diagnosis.
Elevated serum albumin-to-creatinine ratio as a protective factor on outcomes after heart transplantation
Authors: Shen Qiang , Yao Dingyi , Zhao Yang , Qian Xingyu , Zheng Yidan , Xu Li , Jiang Chen , Zheng Qiang , Chen Si , Shi Jiawei , Dong Nianguo
Published: September 2023

Background

The purpose of this study was to investigate the prognostic significance of serum albumin to creatinine ratio (ACR) in patients receiving heart transplantation of end-stage heart failure.

Methods

From January 2015 to December 2020, a total of 460 patients who underwent heart transplantation were included in this retrospective analysis. According to the maximum Youden index, the optimal cut-off value was identified. Kaplan-Meier methods were used to describe survival rates, and multivariable analyses were conducted with Cox proportional hazard models. Meanwhile, logistic regression analysis was applied to evaluate predictors for postoperative complications. The accuracy of risk prediction was evaluated by using the concordance index (C-index) and calibration plots.

Results

The optimal cut-off value was 37.54 for ACR. Univariable analysis indicated that recipient age, IABP, RAAS, BB, Hb, urea nitrogen, D-dimer, troponin, TG, and ACR were significant prognostic factors of overall survival (OS). Multivariate analysis showed that preoperative ACR (HR: 0.504, 95% = 0.352–0.722, P < 0.001) was still an independent prognostic factor of OS. The nomogram for predicting 1-year and 5-year OS in patients who underwent heart transplantation without ACR (C-index = 0.631) and with ACR (C-index = 0.671). Besides, preoperative ACR level was a significant independent predictor of postoperative respiratory complications, renal complications, liver injury, infection and in-hospital death. Moreover, the calibration plot showed good consistency between the predictions by the nomogram for OS and the actual outcomes.

Conclusion

Our research showed that ACR is a favorable prognostic indicator in patients of heart transplantation.
Systemic and local vascular inflammation and arterial reactive oxygen species generation in patients with advanced cardiovascular diseases
Authors: Sulicka-Grodzicka Joanna , Szczepaniak Piotr , Jozefczuk Ewelina , Urbanski Karol , Siedlinski Mateusz , Niewiara Łukasz , Guzik Bartłomiej , Filip Grzegorz , Kapelak Bogusław , Wierzbicki Karol , Korkosz Mariusz , Guzik Tomasz J. , Mikolajczyk Tomasz P.
Published: September 2023

Background

Systemic inflammation may cause endothelial activation, mediate local inflammation, and accelerate progression of atherosclerosis. We examined whether the levels of circulating inflammatory cytokines reflect local vascular inflammation and oxidative stress in two types of human arteries.

Methods

Human internal mammary artery (IMA) was obtained in 69 patients undergoing coronary artery bypass graft (CABG) surgery and left anterior descending (LAD) artery was obtained in 17 patients undergoing heart transplantation (HTx). Plasma levels of tumor necrosis factor α (TNF-α), interleukin-6 (IL-6) and interleukin-1β (IL-1β) were measured using ELISA, high-sensitivity C-reactive protein (hs-CRP) was measured using Luminex, and mRNA expression of proinflammatory cytokines in the vascular tissues was assessed. Furthermore, formation of superoxide anion was measured in segments of IMA using 5 uM lucigenin-dependent chemiluminescence. Vascular reactivity was measured using tissue organ bath system.

Results

TNF-α, IL-6 and IL-1β mRNAs were expressed in all studied IMA and LAD segments. Plasma levels of inflammatory cytokines did not correlate with vascular cytokine mRNA expression neither in IMA nor in LAD. Plasma TNF-α and IL-6 correlated with hs-CRP level in CABG group. Hs-CRP also correlated with TNF-α in HTx group. Neither vascular TNF-α, IL-6 and IL-1β mRNA expression, nor systemic levels of either TNF-α, IL-6 and IL-1β were correlated with superoxide generation in IMAs. Interestingly, circulating IL-1β negatively correlated with maximal relaxation of the internal mammary artery (r = −0.37, p = 0.004). At the same time the mRNA expression of studied inflammatory cytokines were positively associated with each other in both IMA and LAD. The positive correlations were observed between circulating levels of IL-6 and TNF-α in CABG cohort and IL-6 and IL-1β in HTx cohort.

Conclusions

This study shows that peripheral inflammatory cytokine measurements may not reflect local vascular inflammation or oxidative stress in patients with advanced cardiovascular disease (CVD). Circulating pro-inflammatory cytokines generally correlated positively with each other, similarly their mRNA correlated in the arterial wall, however, these levels were not correlated between the studied compartments.