bluuebunny/crossref_metadata_2025 huggingface dataset:
La Influencia de Manuel Gamio en la política educativa intercultural en México a lo largo de cien años
Authors:   UNIVERSIDAD INTERCULTURAL DEL ESTADO DE PUEBLA, Galán López Felipe Javier
Published: September 2023

A lo largo de poco más de cien años, la antropología mexicana ha documentado parte de la historia de los pueblos originarios de sus diferentes regiones culturales, lo que ha permitido que a inicio de siglo XXI, existan en México políticas con enfoque intercultural que no pueden ser analizadas sin la influencia del indigenismo. El legado de generaciones de antropólogos es muy importante. De la lista de investigadores que dedicaron su vida a desarrollar políticas públicas, el trabajo de Manuel Gamio resulta fundamental, pues, además de ser uno de los más conocidos intelectuales del siglo XX, precursor de la antropología mexicana, su pensamiento influyó a la política educativa intercultural, en la ponencia hay un análisis de tres momentos: el indigenismo posrevolucionario, la concepción intercultural de la segunda mitad del s. XX y la ruptura del final de siglo y principio de milenio. El trabajo está dividido en tres partes. En la primera se presenta una serie de reflexiones y debates sobre la antropología de Gamio en relación con la política indigenista. En la segunda se hace una reflexión sobre la importancia de la antropología como ciencia; comprensiva y sus cambios en la década de 1950 y finalmente se analiza la influencia de Gamio en la política intercultural de final de siglo XX y principio de nuevo milenio. La ponencia es parte de capítulo "Repensar a Manuel Gamio, al indigenismo y a la antropología del siglo xx. Reflexiones a 500 años de la invasión", publicado en el libro “A más de 500 años de la invasión de Mesoamérica. Memorias y resistencias de esperanza ngigua, antropología e historia" (UIEP, 2021), coordinado por Guillermo López Varela Fernando Matamoros Ponce Manlio Barbosa Cano Manuel Alfonso Melgarejo Pérez
Transcriptomics-inferred dynamics of SARS-CoV-2 interactions with host epithelial cells
Authors: Adam Lukas , Stanifer Megan , Springer Fabian , Mathony Jan , Brune Maik , Di Ponzio Chiara , Eils Roland , Boulant Steeve , Niopek Dominik , Kallenberger Stefan M.
Published: September 2023

Virus-host interactions can reveal potentially effective and selective therapeutic targets for treating infection. Here, we performed an integrated analysis of the dynamics of virus replication and the host cell transcriptional response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection using human Caco-2 colon cancer cells as a model. Time-resolved RNA sequencing revealed that, upon infection, cells immediately transcriptionally activated genes associated with inflammatory pathways that mediate the antiviral response, which was followed by an increase in the expression of genes involved in ribosome and mitochondria function, thus suggesting rapid alterations in protein production and cellular energy supply. At later stages, between 24 and 48 hours after infection, the expression of genes involved in metabolic processes—in particular, those related to xenobiotic metabolism—was decreased. Mathematical modeling incorporating SARS-CoV-2 replication suggested that SARS-CoV-2 proteins inhibited the host antiviral response and that virus transcripts exceeded the translation capacity of the host cells. Targeting kinase-dependent pathways that exhibited increases in transcription in host cells was as effective as a virus-targeted inhibitor at repressing viral replication. Our findings in this model system delineate a sequence of SARS-CoV-2 virus-host interactions that may facilitate the identification of druggable host pathways to suppress infection.
Bjorken Sum Rule with Analytic Coupling at Low Q2 Values
Authors: Gabdrakhmanov I. R. , Gramotkov N. A. , Kotikov A. V. , Volkova D. A. , Zemlyakov I. A.
Published: September 2023

The experimental data obtained for the polarized Bjorken sum rule $$\Gamma _{1}^{{p - n}}({{Q}^{2}})$$ for small values of Q2 are approximated by the predictions obtained in the framework of analytic QCD up to the fifth order perturbation theory, whose coupling constant does not contain the Landau pole. We found an excellent agreement between the experimental data and the predictions of analytic QCD, as well as a strong difference between these data and the results obtained in the framework of perturbative QCD.
Broad photodynamic antibacterial activity of a functionalized, highly fluorinated sensitizer
Authors: Okorie Mary C. , Yussof Ayuni , Chu Tinchun , Gorun Sergiu M.
Published: September 2023

Acquired resistance allows bacteria to survive antibiotics, a major health problem. Antibacterial photodynamic inactivation (PDI) relies on photoproduction by a photosensitizer of difficult-to-counteract reactive oxygen species (ROS). We report that a -COOH- functionalized fluoroalkyl-rich fluoro zinc phthalocyanine containing 48 F atoms, is soluble and stable in 99:1% H2O:DMF, and produces 1O2 in quantum yields exceeding 0.30. The photosensitizer induces 93.70–97.28% inhibition of Gram-negative E. coli and P. aeruginosa, and Gram-positive B. subtilis and S. aureus. Such durable, functionalized photosensitizers, exhibiting both inert C-F bonds and reactive-COOH groups, unlike perfluorinated phthalocyanines might be advantageous for constructing covalently bonded new materials with long-term bacterial inactivation activity, useful in a variety of operating environments.
Adaptive Integration of Categorical and Multi-relational Ontologies with EHR Data for Medical Concept Embedding
Authors: Cheong Chin Wang , Yin Kejing , Cheung William K. , Fung Benjamin C. M. , Poon Jonathan
Published: September 2023

Representation learning has been applied to Electronic Health Records (EHR) for medical concept embedding and the downstream predictive analytics tasks with promising results. Medical ontologies can also be integrated to guide the learning so the embedding space can better align with existing medical knowledge. Yet, properly carrying out the integration is non-trivial. Medical concepts that are similar according to a medical ontology may not be necessarily close in the embedding space learned from the EHR data, as medical ontologies organize medical concepts for their own specific objectives. Any integration methodology without considering the underlying inconsistency will result in sub-optimal medical concept embedding and, in turn, degrade the performance of the downstream tasks. In this article, we propose a novel representation learning framework called ADORE

(
AD
aptive
O
ntological
RE
presentations)

that allows the medical ontologies to adapt their structures for more robust integrating with the EHR data. ADORE first learns multiple embeddings for each category in the ontology via an attention mechanism. At the same time, it supports an adaptive integration of categorical and multi-relational ontologies in the embedding space using a category-aware graph attention network. We evaluate the performance of ADORE on a number of predictive analytics tasks using two EHR datasets. Our experimental results show that the medical concept embeddings obtained by ADORE can outperform the state-of-the-art methods for all the tasks. More importantly, it can result in clinically meaningful sub-categorization of the existing ontological categories and yield attention values that can further enhance the model interpretability.
IoT-Based Real-Time Crop Drying and Storage Monitoring System
Authors: Viviane Ishimwe , Masabo Emmanuel , Joseph Habiyaremye , Rene Mitsindo , Bizuru Elias
Published: September 2023

Maize flour obtained from the dried corn is one of the most consumed foods in Rwanda. It is imperative that this should be healthy and risk-free for a safe consumption. Therefore, it is vital to keep track of the environmental conditions during the drying process and the characteristics that exist inside maize storage containers. In Rwanda, traditional methods are most commonly used by maize farmers for drying and storage purposes, where no smart system is being used to monitor the environmental conditions under which the maize grains are dried and stored. This mostly affects the quality of maize and flour being produced which will finally affect food security. In this research, temperature, humidity, and light sensors are deployed in the grain storage containers for environmental parameter detection purposes to achieve the primary goal of providing practical, secure, and easily accessible storage in inclement weather. Temperature and humidity are two factors that have an impact on grain quality while in storage. The ThingSpeak platform has been used to help farmers monitor the drying and storing conditions of the maize on a real-time basis. A global system for mobile (GSM) communication module is used to notify farmers by sending a short message in case of critical drying or storing environmental parameters under which the maize grains are stored. The result is shown in the form of humidity, temperature, and light graphs which are displayed on the ThingSpeak platform in real-time mode.
Censoring Balancing Functions for Undetected Probably Significant Effects in Cox Regression
Authors: Nizeyimana Ildephonse , Orwa George Otieno , Ofori Michael Arthur , Mwalili Samuel Musili
Published: September 2023

Weighted Cox regression models were proposed as an alternative to the standard Cox proportional hazards models where consistent estimators can be obtained with more relative strength compared to unweighted cases. We proposed censoring balancing functions which can be built in a way that allows us to obtain the maximum possible significant treatment effects that may have gone undetected due to censoring. The harm caused by this is compensated and new weighted parameter estimates are found. These functions are constructed to be monotonic because even the hazard ratios are not exactly constant as in the ideal case, but are violated by monotonic deviations in time. For more than one covariate, even the interaction between covariates in addition to censoring can lead to the loss of significance for some covariates’ effects. Undetected significant effects of one covariate can be obtained, still keeping the significance and approximate size of the remaining one(s). This is performed by keeping the consistency of the parameter estimates. The results from both the simulated datasets and their application to real datasets supported the importance of the suggested censoring balancing functions in both one covariate and more than one covariate cases.
Adrenal Hemorrhage in Patients with Systemic Lupus Erythematosus and Antiphospholipid Syndrome: A Case Report and Literature Review
Authors: Jiang Weiwei , Chen Danrui , Yang Daizhi , Zeng Longyi , Xu Wen , Lin Shuo
Published: September 2023

Antiphospholipid syndrome (APS) is an autoimmune disorder while adrenal hemorrhage could be its rare complication. Herein, we report the case of a 32-year-old unmarried woman with a history of systemic lupus erythematosus (SLE) who was hospitalized after complaints of upper abdominal pain, limb weakness, and loss of appetite for 2 weeks. Laboratory examination revealed hyponatremia, low plasma cortisol levels, increased adrenocorticotropic hormone levels, and a positive anticardiolipin antibody status. Furthermore, computed tomography (CT) revealed the presence of bilateral adrenal masses. Ultimately, based on dynamic changes in CT images, these masses were diagnosed as adrenal hemorrhage owing to APS. A computer-assisted literature search was conducted to identify cases of primary adrenal insufficiency associated with APS and/or SLE. The clinical features, laboratory examination, treatments, and outcomes of these cases were summarized. Our findings emphasize the importance of screening for adrenal insufficiency in patients with SLE or APS who present with abdominal complaints, asthenia, and hyponatremia. It is also recommended to test for APS all patients with adrenal hemorrhage.
Analysis of interior rotor for high-speed brushless DC motor using finite element method
Authors: Abdullah Nurfaezah , Karim Kasrul Abdul , Othman Raja Nor Firdaus Raja , Jidin Auzani , Sutikno Tole
Published: September 2023

The permanent magnet of brushless DC (BLDC) motor is ideally suited for high-speed application due to its superior performance and efficient as compared to other types of electrical motors. However, to operate in high-speed operation, the rotors that hold the magnet must be able to withstand high centrifugal force. Due to that, the main objective of this project is to design and develop the suitable rotor for high-speed BLDC motor through the finite element method (FEM) Ansys Maxwell modeling software. In addition, this project is also carried out to determine the ability of the modeled software to reach the high-speed performances in terms of cogging torque and induce voltage. In this project, the selected BLDC motor was fabricated and measured experimentally. The result showed that the designed rotor can achieve speed of almost 14,500 rpm.
Online position error correction technique for sensorless control of multipole permanent magnet machines
Authors: Aissou Said , Amirouche Elyazid , Iffouzar Koussaila , Ghedamsi Kaci , Aouzellag Djamal
Published: September 2023

In order to improve the reliability of electric machine drive systems, the position encoder is often replaced with an estimator, such as the extended Kalman filter. However, estimation errors can still occur, especially in machines with high pole number, commonly used in renewable energy systems. The high number of pole pairs amplifies the effect of estimation errors, leading to a substantial divergence between actual and controlled currents, potentially causing harm to the machine through the excessive heat generation or demagnetization of permanent magnets. To address this issue, an error compensation method has been proposed and tested in a control scheme for a tidal stream system based on a multipole dual-star permanent magnet synchronous generator. The method estimates the position error by determining the q-axis permanent magnet flux and correcting it through a PI regulator. Simulation results demonstrate the effectiveness of the proposed method, even with a non-null initial rotor position.
Design and simulation of a TTRH-EV supervisory controller for a proton SAGA 1.3
Authors: Anbaran Sajjad Abdollahzadeh , Idris Nik Rumzi Nik , Aziz Mohd Junaidi Abdul , Sutikno Tole
Published: September 2023

This paper presents modeling and control design steps towards the vehicle hybridization process. The objectives are: a) to model a retrofitted proton SAGA, which is a through-the-road HEV; and b) to design and implement a supervisory control unit for this vehicle. The electric powertrain components required for conversion are sized using the ADVISOR software package. Physical models of both powertrains were modeled using the MATLAB Simscape toolbox and validated for their fidelity. A supervisory controller design and implementation for retrofitted TTRH-EV SAGA is based on the BSFC map and OOL of the engine. The control objective is to restrict engine operation within its optimum window. The controller was implemented using the MATLAB Stateflow toolbox. The complete model of the retrofitted TTRH-EV SAGA, together with the supervisory controller, was tested using standard drive cycles, and the results are presented.
Detection of single line to ground fault and self-extinguishing by using a variable and a fixedable inductance in distribution grid in power
Authors: Jabbar Feryal Ibrahim , Soomro Dur Muhammad , Abdullah Mohd Noor bin , Radzi Nur Hanis binti Mohammad , Baloch Mazhar Hussain , Rahmoon Asif Ahmed , Fakhruldeen Hassan Falah
Published: September 2023

This paper tackled the method for determining the number of Peterson coil which is can compensate with the capacitance because it is important in determining the state of parallel resonance, which in turn control the ground fault current and make the approximate value of the current equal to the current in the sound phases. In this way, we can protect the electrical devices and equipment from being damaged by residual current resulting from the arc due to ground fault, which increases the temperature of conductors which are to a breakdown of insulators and damaging them. Ground fault current equals three times the actual current, and its effect depends on two types of variables which are the first: the number of Peterson coils (which specify the inductance value and compensated) and second: the period time of extinguishing electric are in the ground fault. we obtain, by experimental in the lab where it using the servo motor to control the number of Peterson coils which in turn specify the variable and invariable inductance. We have obtained optimal results for the value of ground-fault current, detect the ground fault and treat it without effect of network load and without power cut off for consumer.
Comparison of control strategies for thermoelectric generator emulator
Authors: Ayop Razman , Tan Chee Wei , Ayob Shahrin Md , Daud Mohd Zaki , Jamian Jasrul Jamani , Nordin Norjulia Mohamad
Published: September 2023

Thermoelectric generator (TEG) can directly convert heat energy into electrical energy. It improves the power efficiency of the energy generation system by converting the power loss in the form of heat produced during the generation process into additional electrical energy. The TEG emulator (TEGE) is a power converter that produces a similar current-voltage characteristic as the TEG. It is a valuable device used to develop and test the TEG-based energy generation system. Nonetheless, the research on the TEGE is still in the early stage. This paper proposed a proper, low-cost, and high-efficient TEGE design using the buck converter. The contribution of the paper covers the TEG model in the form of an array, the buck converter design tailored to the TEGE, and 4 new control strategies proposed for the TEGE. The control strategies are the direct referencing method (DRM), perturb and observed (PnO) method, resistance comparison method (RCM), and resistance feedback method (RFM). The conventional proportional-integral controller is used to maintain a smooth operation during transient and steady-state periods. The results show the merits or demerits for each proposed control strategy based on the accuracy, transient response, stability, overshoot, and efficiency.
Performance inspection of high gain chopper designed to extract optimum output of photovoltaic source
Authors: Akter Khadiza , Motakabber S. M. A. , Alam A. H. M. Zahirul , Yousoff Siti Hajar , Ahmed Sajib , Annur Tania
Published: September 2023

In recent years, the demand for power consumption has increased rapidly to fulfill the energy needs of households and industries worldwide. Solar electricity has emerged as the most practical form of renewable energy in this context. Due to its distinctive qualities such as being clean, quiet, and sustainable. Here, the study and analysis of a non-isolated high-gain chopper for solar photovoltaic (PV) systems are presented, which includes a quadratic cell and voltage doubler circuit (VDC). To ensure the utmost power produced by the solar system, the perturb and observe (P&O)-based maximum power point tracking (MPPT) algorithm is utilized. A quadratic VDC and a DC-DC boost converter are used to raise the PV voltage to a higher level (3.6 times higher with an MPPT controller, and 8 times higher with a battery source). The proposed converter exhibits notable improvements in efficiency, achieving an impressive 94%, which outperforms other state-of-the-art topologies. Additionally, the converter showcases a significant boost in voltage conversion gain, thereby substantiating its efficacy and superiority over other advanced topologies. Furthermore, comparatively less voltage stress on the switch with reduced voltage and current fluctuation increased the conversion effectiveness of the proposed configuration. Performance verification of the proposed topology is obtained by employing PSIM and MATLAB/Simulink.
Grid power control of direct matrix converter fed three-phase induction generator
Authors: Al-Khayyat Ali Salam , Kadhem Human Qahtan , Hameed Mustafa Jameel
Published: September 2023

The direct matrix converter (DMC) and the modulation technique were presented in this paper, moreover the power of the grid is controlled. Due to its high flexibility and low computation demands, the DMC's most widely used modulation technique is space vector modulation. The double-side modulation is used in this paper instead of the single-side modulation because less harmonics at the input and output side can be obtained, however this would increase slightly the number of branch-switch-overs (BSO) for each switching period. In addition to being able to create input and output sinusoidal currents with various frequencies, it would adjust the input power factor. Along with that, the simple power control loop would regulate the grid power and then generate controlled three-phase reference signals for pulses generation accordingly. Results from the simulations show that the topology is appropriate for machine drive applications.
Switch mode power supply with flyback LED driver topology in public lighting systems energy supply
Authors: Widjonarko Widjonarko , Hardianto Triwahju , Akmal Ahmad Ishamul Ayady , Ate Abdelrahim Ahmed  Mohammed
Published: September 2023

This research aims to design a flyback topology switch-mode power supply constant voltage and constant current light emitting diode (LED) driver to improve the performance of the LED. The flyback topology is chosen for its simple design and small size and uses high-frequency switching to lower the high DC voltage from the power source. The research aims to avoid blackouts caused by a drop in the power source voltage and to produce technological products that can be developed for other lighting applications. The constant-voltage feedback system ensures that the current flowing to the LED remains stable despite changes in load or other conditions. When there is a voltage drop from the power source, this topology can maintain the voltage and current stable and in accordance with the working voltage specifications of the LEDs. According to test results, the LED driver's output voltage ranges from 18.03 to 18.06 volts with an average message error value of 0.3%. In this system, switching occurs at frequencies ranging from 18.041 Hz to 38.230 Hz. With a constant current value of 0.58 ampere, the resulting lamp's lux value is stable and does not significantly change.
Assessing annual energy production using a combination of lidar and mast measurement campaigns
Authors: Mkhaitari Rachid , Mir Yamina , Zazoui Mimoun
Published: September 2023

The current study evaluates the wind potential at early stage of wind project using met mast and lidar. The wind data obtained from a met mast located away from the turbines can be hindered by obstacles, leading to limited coverage and height, it negatively impacting the project's performances. To address the above limitations, the study suggests implementing a secondary measurement approach utilizing Lidars in various locations to cover the full study area. This work assesses the two measurements campaign and compares the wind potential evaluated with data measured by met mast and lidars. The simulations of two wind data base are quantified referring to the main key performance indicators for a project of total capacity of 140MW. The results show significant improvement in gross and net production for all exceedance scenarios, with 2% increase on the P90, and an improvement in the annual capacity factor by 1.09%. The use of Lidar data referenced to a met mast leads to accurate and bankable data, with the advances of cost and logistics, Lidars helps in layout configuration and performance evaluation.
Simulation analysis of DC motor based solar water pumping system for agriculture applications in Rural areas
Authors: Gurgi Zeina K. , Abdalla Ali I. , Hassan Enas D.
Published: September 2023

Solar photovoltaic (PV) generators for agriculture purposes offer a practical alternative over traditional electricand diesel-based water pumps due to their low cost, sustainable and eco-friendly nature. These systems are suitable for remote locationsin case of unreachablepower grid. However,the operation of these generators is affected by various factor such weather statusThis article proposes a photovoltaic water pumping system (PVWPS) to drive a centrifugal pump using a permanent magnet DC motor (PMDC).  Additionally, a boost converter for extracting the maximum power from PV panels was used in the system and an Incremental conductance (IC) algorithm was chosen in the controller circuit. The system was implemented and investigated using MATLAB/Simulink at various irradiance values (i.e., 400, 600, 800 and 1000) w/m2. The results indicate that the efficiency of the proposed system is higher than 90% at all selected irradiance values proven that the integration of PV array with water pumping system without any energy storage devices is applicable at a daytime.
Impact of integration of renewable energies and energy efficiency on the reliability of the national electricity grid
Authors: Karmich Saida , Ziani El Mostafa , Bouchnaif Jamal , El Malki Mohamed
Published: September 2023

This article consists of studying the reliability of the Moroccan electricity grid as well as verifying the plan of production for 2030. To propose an adequate production plan for 2050, a production plan where renewable energies take a large place in the production park. Our objective is the planning and optimization of the Moroccan energy system with a strong integration of renewable energy sources or even 100% integration by guaranteeing the reliability of the electrical system. In this study, we evaluated the reliability of the Moroccan electricity grid in the presence of renewable electricity production based on the energy plan simulator supplemented by Monte Carlo simulations based on probabilistic approaches. The first part of this work consists of projecting demand for 2030-2050 and studying the impact of energy efficiency on forecasts. In the second part, we integrated the existing means of production and the projected demand on energy plan. In the third part we studied the reliability of the Moroccan electricity grid in the presence of the production of wind, solar photovoltaic (PV) and concentrated solar (CSP) electricity according to different stages of study (from 2017 to 2050).
Metaheuristics-based maximum power point tracking for PV systems: a review
Authors: Jamhari Muhammad Khairul Azman Mohd , Hashim Norazlan , Othman Muhammad Murtadha , Abidin Ahmad Farid Bin
Published: September 2023

Over the years, numerous maximum power point tracking (MPPT) methods have been developed to extract the maximum available power from PV arrays. They are generally categorized as conventional or metaheuristic methods. The most employed conventional methods include perturb and observe (P&O), hill climbing (HC), and incremental conductance (INC), due to their simplicity and ease of implementation. However, under partial shading condition (PSC), none of them can effectively locate a global maximum power point (GMPP) out of many local maximum power points (LMPPs). This results in significant power loss during PSC, prompting the development of various metaheuristic-based MPPT methods to address the problem. This paper reviews 38 existing metaheuristic-based MPPTs and 27 metaheuristic methods that have not yet been applied to any MPPT operation up to date. Metaphorically, these methods are divided into four categories: (i) evolutionary-based, (ii) physics-based, (iii) swarm-based, and (iv) human-based. The different MPPTs are compared in terms of complexity, converter topology, and PSC tracking capability. This paper is intended to serve as a one-stop resource for any researcher, practitioner, or advanced student seeking to develop a new metaheuristic-based MPPT method.
First record of the Western Himalayan Yew Taxus contorta (Gymnosperms: Cupressales: Taxaceae) from Lumbini Province, Nepal
Authors: Thing Santa Bahadur , Shahi Deepak Raj Prakash Jung , Shrestha Shashi
Published: September 2023

The threatened Western Himalayan Yew is one among three of the Taxus species found in Nepal. During the transect walk survey conducted on March-April 2021, we recorded Taxus contorta in at least 55 locations in the northern aspect, along the wet sites and away from human dominated landscape.
Phylogenetic insights on the delineation of Mysore and Malabar subspecies of the Grey Slender Loris Loris lydekkerianus in southern India
Authors: Teja Vinay , Manu Shivakumara , Kumara Honnavalli N. , Umapathy Govindhaswamy
Published: September 2023

Slender lorises are a threatened genus of small and nocturnal strepsirrhine primates confined to India and Sri Lanka. The Grey Slender Loris Loris lydekkerianus is divided into several subspecies based on morphological variation and geographical distribution but not supported by molecular data. We investigated the phylogenetic divergence of two subspecies of the Grey Slender Loris in southern India: the Mysore Slender Loris Loris lydekkerianus ssp. lydekkerianus and the Malabar Slender Loris Loris lydekkerianus ssp. malabaricus. We generated whole genome shotgun sequence data and assembled the whole mitochondrial genomes of representative individuals from their distribution in southern India and compared them with publicly available mitogenomes of other lorises. We found that the Mysore and Malabar Slender Lorises vary by 2.09% in the COX1 and CYTB gene regions. Further, phylogenetic analysis of 13 protein-coding and two ribosomal RNA genes in the mitochondrial genome showed that the Mysore and Malabar Slender Lorises form distinct monophyletic clades that diverged about 1.049 million years ago, shortly after the divergence of Red Slender Loris Loris tardigradus. Considering this relatively high sequence variation and evolutionary divergence together with their already established morphological differences and geographically distinct habitats, we propose to recognize the Mysore and Malabar Slender Lorises as two distinct species Loris lydekkerianus and Loris malabaricus.
Diversity of powdery mildew fungi from protected areas of Jizzak region, Uzbekistan - a checklist
Authors: I.M. Mustafaev  , I.Z. Ortiqov  , K.K. Nuraliev  , D.S. Khujaqulova
Published: September 2023

The first-ever compilation of a checklist for powdery mildew fungi within the protected areas of Uzbekistan’s Jizzakh region, specifically Nuratau Nature Reserve, Zaamin National Nature Park, and Zaamin Nature Reserve is presented through this study. Field research spanning from 2009 to 2022 facilitated this comprehensive endeavor. A comprehensive identification process revealed a total of nine groups, consisting of 57 distinct types, 69 variations, and four different strains of powdery mildew. Two species, namely Erysiphe platani and E. syringae, were newly identified within the mycobiota of the country. Additionally, the plant index of Uzbekistan documented 11 powdery mildew species and ten variations on 18 previously unrecorded host plant species. Most species of powdery mildew fungi belong to the genera Erysiphe and Leveillula. The annotated checklist includes data on the host plant, location, date and collection number of every species.
Microvascular Dysfunction as a Possible Link Between Heart Failure and Cognitive Dysfunction
Authors: Hillier Elizabeth , Covone Jason , Fischer Kady , Chen Hao Yu , Hafyane Tarik , Friedrich Matthias G.
Published: September 2023

BACKGROUND:

Microvascular function in the brain and heart may play an important role in the course of patients with heart failure (HF), but its relationship with ventricular and cognitive function is not well understood. We hypothesized that microvascular function in HF is closely related to both, cardiac and cognitive function.

METHODS:

In healthy controls and symptomatic patients with HF (New York Heart Association functional class II or III), we used oxygenation-sensitive magnetic resonance imaging during a standardized breathing maneuver to determine the cerebral oxygenation reserve and the myocardial oxygenation reserve (MORE) as markers for microvascular function. A stepwise multivariable linear regression was performed to determine the variables that best predict changes in cerebral oxygenation reserve and MORE. We also measured cognitive function using the Montreal Cognitive Assessment test.

RESULTS:

Twenty patients with HF (age 64.4±8.3 years; 50% female sex), and 21 healthy controls (age 55.0±5.1 years; 62% female sex) were included in the analysis. In patients with HF, cerebral oxygenation reserve and MORE were lower than in healthy controls (MORE, −0.1±3.3 versus 5.0±4.2, cerebral oxygenation reserve: 0.43±0.47 versus 1.21±0.60, respectively) as were Montreal Cognitive Assessment score results (HF, 23.9±3.7; healthy, 27.8±1.5;
P
=0.002). The Montreal Cognitive Assessment score in patients was correlated with cardiac output (
r
=0.55,
P
=0.011) and MORE (
r
=0.46,
P
=0.040). In addition to the presence of HF, significant predictors of cerebral and myocardial oxygenation reserve were cardiac output and end-diastolic volume, respectively.

CONCLUSIONS:

Our results indicate that heart failure is an independent predictor of coronary and cerebral microvascular dysfunction as defined by a reduced response to a vasodilatory breathing maneuver. This impaired response was associated with reduced cognitive function.
Validation of a Deep Learning Algorithm for Continuous, Real‐Time Detection of Atrial Fibrillation Using a Wrist‐Worn Device in an Ambulatory Environment
Authors: Poh Ming‐Zher , Battisti Anthony J. , Cheng Li‐Fang , Lin Janice , Patwardhan Anil , Venkataraman Ganesh S. , Athill Charles A. , Patel Nimesh S. , Patel Chinmay P. , Machado Christian E. , Ellis Jeffrey T. , Crosson Lori A. , Tamura Yuriko , Plowman R. Scooter , Turakhia Mintu P. , Ghanbari Hamid
Published: September 2023

Background

Wearable devices may be useful for identification, quantification and characterization, and management of atrial fibrillation (AF). To date, consumer wrist‐worn devices for AF detection using photoplethysmography‐based algorithms perform only periodic checks when the user is stationary and are US Food and Drug Administration cleared for prediagnostic uses without intended use for clinical decision‐making. There is an unmet need for medical‐grade diagnostic wrist‐worn devices that provide long‐term, continuous AF monitoring.

Methods and Results

We evaluated the performance of a wrist‐worn device with lead‐I ECG and continuous photoplethysmography (Verily Study Watch) and photoplethysmography‐based convolutional neural network for AF detection and burden estimation in a prospective multicenter study that enrolled 117 patients with paroxysmal AF. A 14‐day continuous ECG monitor (Zio XT) served as the reference device to evaluate algorithm sensitivity and specificity for detection of AF in 15‐minute intervals. A total of 91 857 intervals were contributed by 111 subjects with evaluable reference and test data (18.3 h/d median watch wear time). The watch was 96.1% sensitive (95% CI, 92.7%–98.0%) and 98.1% specific (95% CI, 97.2%–99.1%) for interval‐level AF detection. Photoplethysmography‐derived AF burden estimation was highly correlated with the reference device burden (
R
2
=0.986) with a mean difference of 0.8% (95% limits of agreement, −6.6% to 8.2%).

Conclusions

Continuous monitoring using a photoplethysmography‐based convolutional neural network incorporated in a wrist‐worn device has clinical‐grade performance for AF detection and burden estimation. These findings suggest that monitoring can be performed with wrist‐worn wearables for diagnosis and clinical management of AF.

Registration Information

URL:
https://www.clinicaltrials.gov
; Unique identifier: NCT04546763.
Earthly fruitfulness and the gods of nature in Rubens’ imagery
Authors: Mcgrath Elizabeth
Published: September 2023

This article explores themes of fertility and fecundity in Peter Paul Rubens’ work and investigates their role in a peculiar Rubensian category of subject, somewhere between landscape and myth, which can perhaps be described as ‘mythological genre’. Here we see the ancient gods of nature inhabiting the countryside and engaged in their ‘everyday’ activities, though, as in The feast of Venus (Vienna, Kunsthistorisches Museum), their presence is usually sensed rather than seen by any human characters depicted alongside them.

A particular focus of the article is one of Rubens’ most personal works, the Nymphs and satyrs gathering fruit (Madrid, Museo del Prado). It was his happy invention to give the nymphs, satyrs and even the old Silenus the job of collecting fruit together, to keep the cornucopia – symbol of abundance and fecundity – in a state of constant overflow. It has not been realised, however, that Rubens had a classical source for the idea of Silenus and the satyrs helping the nymphs gather apples: a passage in Propertius’ Elegies (II.32.37-40).

The poetry of Propertius was especially familiar to Rubens’ circle as Justus Lipsius planned an edition of the poet’s work. Moreover, the lines had been the subject of a notable emendation by Joseph Justus Scaliger, as well as an extensive discussion by Lipsius in his Antiquae lectiones (III). Rubens was surely familiar with the Propertius passage, whether he came across it in his reading or in his conversations on ancient literature and customs with his brother, Philip, Lipsius’ favourite pupil. In Nymphs and satyrs, the poet’s lines seem to have helped inspire a joyous celebration of the earth’s fruitfulness by the gods of nature themselves.
Description of two new species of Cerambycidae and new records and notes on American Cerambycidae and Disteniidae (Coleoptera)
Authors: BEZARK LARRY G. , SANTOS-SILVA ANTONIO
Published: September 2023

Two new species are described: Dihammaphora erecta sp. nov. (Cerambycinae, Rhopalophorini), from Ecuador; and Colombicallia contraria sp. nov. (Lamiinae, Calliini), from Mexico (Veracruz). Dihammaphora erecta sp. nov. is included in a previous key. Twelve new records from Mexico, Central America, and South America are provided. Variations of the elytral pubescent patterns in Aegomorphus consentaneus and A. polystictus (Bates, 1885) are reported. The unknown female of Aegomorphus cunninghami is examined and illustrated for the first time, and notes on the differences with males are provided. Variation in the pubescent pattern in Aegomorphus quadrigibbus (Say, 1831) is reported.
Badis limaakumi, a new species of badid fish from Nagaland, Northeast India (Teleostei: Percomorpha: Badidae)
Authors: PRAVEENRAJ JAYASIMHAN
Published: September 2023

Badis limaakumi, a new species of Badis from Nagaland, Northeast India is distinguished from all its congeners by the following combination of characters: a large (>60 mm SL) and slender body (23.2–28.0% of SL), presence of an opercular blotch at the base of the opercular spine, absence of blotches on the sides and fins, as well as on the cleithrum, and greater number of lateral-line scales.
The role of magnetic resonance imaging in the management of brain metastases: diagnosis to prognosis
Authors: Zakaria Rasheed , Das Kumar , Bhojak Maneesh , Radon Mark , Walker Carol , Jenkinson Michael D
Published: September 2023

This article reviews the different MRI techniques available for the diagnosis, treatment and monitoring of brain metastases with a focus on applying advanced MR techniques to practical clinical problems. Topics include conventional MRI sequences and contrast agents, functional MR imaging, diffusion weighted MR, MR spectroscopy and perfusion MR. The role of radiographic biomarkers is discussed as well as future directions such as molecular imaging and MR guided high frequency ultrasound.
Association between sun-protective behaviors and hypertension: a cross-sectional study from National Health and Nutrition Examination Survey 2009 to 2014
Authors: Yang Shuping , Dai Feng , Wang Zhaokai , Li Ruoshui , Xu Xianzhi , Li Cheng , Hou Xiancun , Liu Yang , Wang Chaofan , Li Dongye , Li Lei , Xu Tongda
Published: September 2023

Background

In previous studies, sun-protective behaviors increased cardiovascular incidence. Our present article is to further analyze the potential relationship between sun-protective behaviors (staying in the shade, wearing long-sleeved clothing, and applying sunscreen) and hypertension.

Method

The present cross-sectional study evaluated 8,613 participants (aged 20–60 years) from the National Health and Nutrition Examination Survey (NHANES) obtained between 2009 and 2014. We performed multiple logistic regression analysis to examine the relationship between sun-protective behaviors and hypertension. Subgroup analysis was then performed. Multiple linear regression analysis was utilized to examine the relationship of sun-protective behaviors and each sun-protective behavior with systolic and diastolic blood pressure, stratified by sex and race.

Results

A total of 8,613 participants (weighted n = 127,909,475) were applied in our study, including 1,694 hypertensive subjects. Our study demonstrated that sun-protective behaviors of the 2–3 category were associated with increased risk of hypertension, but not with higher systolic and diastolic blood pressure. In subgroup analysis, men, Mexican American, and 25 < BMI ≤ 30 who reported sun-protective behaviors (2–3) were prone to hypertension. Multiple linear regression models showed that non-Hispanic white men with sun-protective behaviors (2–3) were positively associated with systolic and diastolic blood pressure. The association between other-Hispanic men with frequent wearing long-sleeved clothing and diastolic blood pressure was positively correlated.

Conclusion

Sun-protective behaviors of the 2–3 category could increase the incidence of hypertension, but not increase systolic and diastolic blood pressure. We only found that non-Hispanic white men who reported sun-protective behaviors (2–3) were positively associated with systolic and diastolic blood pressure. These findings suggested that excessive sun-protective behaviors should be avoided.
The lowest point of fibula (LPF) could be used as a reliable bony landmark for arthroscopic anchor placement of lateral ankle ligaments ----compared with open Broström procedure
Authors: Xie Xin , Chen Linxin , Fan Cunshuai , Song Shouyi , Yu Yin , Jiao Chen , Pi Yanbin
Published: September 2023

Background

Arthroscopic technique procedures was wide accepted for the treatment of chronic ankle instability (CAI). But little acknowledge was involved to the bony landmarks and anatomic features of different bundles of lateral ligaments under arthroscopic view.

Methods

Sixty patients with acute or chronic lateral ankle ligaments injury (LAI) were collected prospectively, and divided randomly into two groups. In arthroscopic group, the bone tunnels were made on the LPF arthroscopically. And in open group, the bone tunnels were made on the Fibular obscure tubercle (FOT) in open procedure. The inferior bundle of ATFL and Arcuate fibre was also identified reference to the LPF and labeled by a PDS II suture penetration. Following that, The distances of the bone tunnels to the different bony markers were measured and compare between two groups. The penetrating locations of PDS II on the inferior bundle of ATFL and Arcuate fibre were also confirmed intraoperatively. And the safe angle of anchor implantation on the axial view was measured on postoperative CT scan.

Results

The distances of bone tunnel to the fibular tip, the fibular insertion of anterior-inferior tibiofibular ligament (AITFL), and the FOT in arthroscopic and open locating groups were 4.9 ± 2.2 and 6.3 ± 2.2 mm, 13.5 ± 2.7 and 12.4 ± 1.1 mm, 5.8 ± 2.2 and 5.6 ± 1.0 mm, respectively. The distances of bone tunnels to the FOT and fibular tip on 3d-CT view was 4.4 ± 1.5 and 4.6 ± 0.9 mm, 14.4 ± 3.2 and 13.2 ± 1.8 mm in arthroscopic and open group, and there were no significant differences between two groups. The safe angle of arthroscopic anchor placement on the axial plan was ranged from 24.9 ± 6.3o to 58.1 ± 8.0o. The PDS II sutures penetrating on the inferior bundles of ATFL and the arciform fibres were also comfirmed successfully by open visualizaion.The average distance of penetration point to the horizontal line cross the fibular tip was 2.3 ± 2.7 mm (ranged from − 3.1 to 6.0 mm), and to the vertical line cross the FOT was 2.7 ± 2.7 mm (ranged from − 2.5 to 7.5 mm).

Conclusion

Take the lowest point of fibula under arthroscopy (LPF) as a bony reference, we could identify the iATFL under arthroscopic visualization. By this way, we could place the suture anchors properly to the fibular footprint and suture the iATFL fibres successfully.
Laparoscopic hiatal hernia repair for treating patients with massive hiatal hernia and iron-deficiency anaemia
Authors: Aili Aikebaier , Maimaitiming Maimaitiaili , Li Yiliang , Maisiyiti Alimujiang , Wang Zhi , Tusuntuoheti Yusujiang , Abudureyimu Kelimu
Published: September 2023

Background

Massive hiatal hernias may result in extraoesophageal symptoms, including iron-deficiency anaemia. However, the role played by hiatal hernias in iron-deficiency anaemia is not clearly understood. We examined the prevalence of anaemia in patients with massive hiatal hernias and the frequency of anaemia resolution after laparoscopic hiatal hernia repair at long term follow-up.

Methods

Patients who underwent laparoscopic hiatal hernia repair from June 2008 to June 2019 were enrolled in this study. We collected the patients’ demographic and clinical data from their medical records, and compared the pre-surgical and post-surgical findings (at 1 week and 3 months post-surgery). All patients with adequate documentation underwent post-surgical follow-up to evaluate improvements in clinical symptoms and signs.

Results

A total of 126 patients with massive hiatal hernias underwent laparoscopic hiatal hernia repair. Of these, 35 (27.8%) had iron-deficiency anaemia. Anaemia was resolution in all the patients and they had significantly reduced GERD-Q scores at 3 months postoperatively (P<0.01) .The mean follow-up period was 60 months. Iron-deficiency anaemia resolution after hiatal hernia repair was achieved in 93.9% of the patients.

Conclusion

Anaemia is common in patients with massive hiatal hernias, and most of our patients were symptomatic because of their anaemia. Moreover, in patients with massive hiatal hernias, iron-deficiency anaemia resolution is likely after laparoscopic hiatal hernia repair.