bluuebunny/crossref_metadata_2025 huggingface dataset:
The Social Ontology of Democracy
Authors: Frega Roberto
Published: March 2019

This paper offers an account of the social foundations of a theory of democracy. It purports to show that a social ontology of democracy is the necessary counterpart of a political theory of democracy. It notably contends that decisions concerning basic social ontological assumptions are relevant not only for empirical research, but bear a significant impact also on normative theorizing. The paper then explains why interactionist rather than substantialist social ontologies provide the most promising starting point for building a social ontology of democracy. It then introduces and examines the three notions of habits, patterns of interaction, and forms of social organization, conceived as the main pillars of an interactionist social ontology of democracy and briefly discusses some major implications of this approach for democratic theory.
Comparing Non-destructive Mechanical Testing Methods for the Assessment of Brittle Papers – The Cantilever, Hanging Pear Loop, and Clamped Fold Tests
Authors: Hall Andrea K. I. , Plaut Raymond H. , McGuiggan Patricia M.
Published: March 2019

The ability to determine the condition of paper (e.g. its brittleness) and its permanence is a need in libraries and archives. This study investigates various bend tests and applies these tests to aged paper with the goal of finding easy, non-destructive tests to determine the mechanical properties of paper. The cantilever test was previously shown to accurately assess mechanical properties of paper-based materials, such as elastic and bending moduli as well as the bending length. This work investigates the hanging pear loop and clamped fold tests and compares the results with those found with the cantilever test. The results show that the strain and curvature induced by the two tests are much larger than those experienced in the cantilever test. This large strain and curvature induce plastic behaviour and make the hanging pear loop and clamped fold tests inappropriate for use on paper-based materials.
Semiosis is cognitive niche construction
Authors: Atã Pedro , Queiroz João
Published: March 2019

Here we describe Peircean post-1903 semiosis as a processualist conception of meaning, and relate it to contemporary active externalism in Philosophy of Cognitive Science, especially through the notion of cognitive niche construction. In particular, we shall consider the possibility of integrating (a) the understanding of “semiosis as process” within Peirce’s mature semiotics with (b) an elaboration of the concept of cognitive niche from the point of view of niche construction theory and process biology research.
DOĞAL RENK MADDESİ KATKILI SERT ŞEKERLEME ÜRETİMİ: FARKLI KARBONHİDRAT FORMÜLASYONLARININ RENK, CAMSI GEÇİŞ, HİGROSKOPİTE, KARBONHİDRAT KOMPOZİSYONU VE DUYUSAL ÖZELLİKLER ÜZERİNE ETKİLERİ
Authors: YILMAZ Fatih Mehmet , YILDIRIM Ebru , KARAKUŞ Merve
Published: March 2019

Bu çalışmanın amacı sakaroz, sorbitol
ve glikozun yer aldığı üç farklı karbonhidrat formülasyonu kullanarak
renklendirilmiş sert şeker üretmektir. Bu kapsamda, siyah havuç konsantresi (SHK)
katkılı ve katkısız olarak altı farklı sert şeker %100 sakaroz, %76 sakaroz +
%24 sorbitol, %76 sakaroz + %24 glikoz olarak formüle edilerek üretilmiş ve bu
ürünlerin renk, karbonhidrat kompozisyonu, camsı geçiş, higroskopite ile
duyusal özellikleri değerlendirilmiştir. En yüksek higroskopite değerlerinin
sorbitolün yer aldığı formülasyonlara ait olduğu tespit edilmiş ve SHK
kullanımı tüm formülasyonlarda SHK katkısızlara kıyasla sert şekerlerin
higroskopitelerinin önemli ölçüde azalmasını sağlamıştır (P <0.05).
Duyusal analiz sonuçlarına göre, SHK katkılı ve katkısız en çok beğenilen
ürünün glikozun yer aldığı formülasyonlar olduğu belirlenmiş, bunu sorbitol
takip etmiştir. Diferansiyel taramalı kalorimetre (DSC) analiz sonuçlarının,
yüksek performanslı sıvı kromatografisi (HPLC) ile karbonhidrat kompozisyonu,
duyusal analiz ve higroskopite analizi sonuçlarıyla ilişkilendirilebilir
nitelikte olduğu görülmüştür.
A myocardialis necrosis mértékének vizsgálata eltérő supraventricularis szívritmuszavarok rádiófrekvenciás katéterablatiós kezelését követően
Authors: Tahin Tamás , Herczeg Szilvia , Gellér László , Boros András Mihály , Kovács Orsolya Mária , Szegedi Nándor , Fórizs Éva , Szilágyi Szabolcs , Osztheimer István , Merkely Béla , Széplaki Gábor
Published: March 2019

Abstract:

Introduction: Levels of cardiac necroenzymes, high-sensitive troponin (hsTnT) and creatine kinase muscle-brain (CKMB) increase as a result of a myocardial damage following catheter ablation. Aim: To analyze the mid-term alteration of hsTnT and CKMB levels following radiofrequency ablation (RFCA) for atrial fibrillation (AF), atrial flutter (AFlu), AV-nodal reentry tachycardia (AVNRT) and electrophysiological studies (EPS) without ablation. Method: Patients undergoing RFCA for various indications and EPS were consecutively enrolled in our prospective study. Concentrations of hsTnT and CKMB were measured from serial blood samples directly before and after the procedure, 4 and 20 hours later and at 3 months follow-up. Results: Forty-seven patients (10 EPS, 12 AVNRT, 13 AFlu, 12 AF) with mean age of 55 ± 13 were included. hsTnT levels increased significantly in all groups after the procedures, while CKMB changed only in the AF group. hsTnT exceeded the reference value in all patients with ablation and in 80% of patients with EPS 4 hours post-ablation. Peak average hsTnT levels for EPS, AVNRT, AFlu were 24 ± 11, 260 ± 218 and 541 ± 233 ng/L, respectively. The highest hsTnT level was measured in the AF group (799 ± 433 ng/L). We found a positive correlation between hsTnT levels and ablation time after RFCA. Conclusions: The hsTnT levels significantly change after EPS and RFCA, in all patients who underwent ablation, and in 80% of those with EPS had hsTnT positivity in the early post-procedural phase. hsTnT levels depended significantly on the type of the subgroups and correlated with the ablation time. Awareness of those observations is essential to correctly interpret elevated hsTnT levels following RFCA. Orv Hetil. 2019; 160(14): 540–548.
Karakterisasi Penampilan Reproduksi Sapi Aceh Betina Sebagai Sumber Daya Genetik Ternak Lokal di Kota Subulussalam
Authors: Novita Cut Intan , Sari Eka Meutia , Rahma Erlisa
Published: March 2019

ABSTRAK. Penelitian ini bertujuan untuk mengetahui penampilan reproduksi sapi Aceh betina. Penelitian ini dilakukan di Kota Subulussalam Provinsi Aceh yang meliputi lima kecamatan, yaitu  kecamatan Simpang Kiri, Rundeng, Longkip, Penanggalan dan Sultan Daulat. Penelitian dilakukan selama satu bulan (23 Januari sampai 23 Februari 2017). Metode survei digunakan dalam penelitian ini. Penentuan responden adalah dengan menggunakan metode Purposive Sampling yaitu mengambil sampel dengan persyaratan minimal peternak memelihara satu ekor sapi Aceh yang telah beranak dua kali. Sebagai responden ditetapkan sebanyak 30 petani. Dari hasil penelitian ini dapat disimpulkan bahwa kinerja reproduksi sapi Aceh baik, usia pubertas mencapai usia 1-2 tahun, nilai rata-rata pelayanan per konsepsi adalah 1,5 dan jarak beranak 12,97 bulan.(Characterization of reproductive performans of aceh cattle as local animal genetic resources in subulussalam city)ABSTRACT. This study aims to determine the characterization of reproductive performance of Aceh cattle. This study was conducted in Subulussalam City of Aceh Province covering five districts of Simpang Kiri, Rundeng, Longkip, Penanggalan and Sultan Daulat. The study was conducted for one month (January 23 to February 23, 2017). Survey method was used in this research. Determination of respondent is by using method of Purposive Sampling that is taking sample with minimum requirement of breeder to keep one Aceh cattle that have gave birthtwo times. As the respondents set as many as 30 farmers. From the results can be concluded that the performance of Aceh cattle reproductive is good, age of puberty reached at age 1-2 years, the average value of service per conception is 1.5 and calving interval 12.97 month.
Pharmacoeconomic Analysis of Using Different Types of Monofocal Intraocular Lenses for Cataract Surgery in Russia
Authors: Krysanov I. S. , Krysanova V. S. , Ermakova V. Yu.
Published: March 2019

Purpose: To perform cost-effectiveness analysis of using different types of monofocal intraocular lenses (IOL) for cataract surgery in adults in Russian Federation.Materials and methods. MS Excel based model of medical care patients with cataract has been developed for 1 patient undergoing surgery treatment. “cost-effectiveness” and “budget impact” analyses (BIA) were used to measure the costs associated with cataract treatment with different types of monofocal IOLs for the state budget. Direct medical costs included IOLs cost, treatment of PCO with neodymium-doped uttrium aluminium garnet laser capsulotomy (Nd:YAG), side effects treatment associated with Nd:YAG and were calculated from the Russian healthcare system perspective.Results. Cost-effectiveness analysis among monofocal IOLs demonstrated that the lowest costs for 1 case of successful cataract surgery followed by implantation of the IOL are connected with the use of the AcrySof® Single Piece model — 4,938 rubles, the largest costs — using the Tecnis® One model — 11,753.5 rubles. The use of others hydrophobic IOLs on the AcrySof® platform demonstrated economic feasibility, analyzed models have costs for 1 effective cataract treatment -AcrySof® IQ 9,858 rubles, AcrySof® Natural 6,452 rubles. The conducted BIA has showed that direct medical costs for surgical treatment of cataracts with the implantation of monofocal IOLs from different manufacturers for 100 patients amount to 708,121 rubles. If ua monofocal IOL are used alone on an AcrySof® platform, the cost will be 691,261 rubles, the difference is in favor of monofocal IOL on an AcrySof® platform — 16,860 rubles.Conclusion. Using AcrySof® IOLs for cataract surgery in adult patients is an effective and an economically justified treatment option in Russia Federation.
Tangential Scleral Myopexy (TSM) as an Alternative to Muscle Resection in Strabismus Treatment
Authors: Pivovarov N. N. , Surkova E. N.
Published: March 2019

To present the new method as a variant of minimal invasive strabismus surgery (MISS) technique for less invasive and faster reсtus muscle plication. Extraocular muscle strengthening is common for strabismus treatment. Plication as an alternative for tightening or strengthening muscles appears to be less traumatic, quicker and vascular preserving operation. A new plication variant performed by fixating the edge of muscle with 6-0 vicril sutures and pulling them forward and oversewn at 2–3 mm from external part sclera-tendon joint avoiding the anterior ciliary artereies. The distance of muscles advancement depends on the eye deviation angle and calculated by Kenneth Wright charts. In all patients fornix transconjunctival access was performed. Proposed trapezoidal scleral myopexy (TSM) was performed in 26 patients at the age from 3 to 32 years old (children 3–15 y.o. = 29; adults 20–32 y.o. = 7). 23 consecutive patients underwent TSM combined with antagonist recession at the same eye (15 esotropia, 11 exotropia). Follow up period was 6–26 months. The results were considered satisfactory if the postoperative angle was between 0 ± 3° (92.3 %). Only 2 cases (7.6 %) failed to reach this standart. The obtained results considered as very satisfactory. Patients reported only minimal postoperative discomfort and no complain on cosmetics. Trapezoidal muscle plication was inconspicuous throught the conjunctive. The good results of TSM proposed by the author seems to be very simple and more effective for muscle strengthening comparing to resection of medial and lateral rectus muscles. Placement of sutures at the muscle edge during trapezoidal plication exclude ciliary vassel destruction and anterior segment ischemia. The obtained results demonstrated that TSM was considered to be equivalent to resection of horizontal rectus and especially of vertical rectus muscles. Trapezoid form of plication increases the arc of sclera contact to the muscle, probably, explaining the efficiency of proposed operation for muscle strengthening. Proposed modification of muscle plication is reversible, simple, sparing for ciliary artery procedure and is recommended as minimal invasive strabismus surgery (MISS) for simultaneous operation on multiple rectus muscles.
Autoimmune Uveitis. Review
Authors: Plekhanov A. N. , Fomina A. S. , Sverkunova O. P. , Ivanova J. V.
Published: March 2019

For many years in ophthalmology there is a complex intractable problem associated with inflammation of the vascular membrane of the eye, the so-called uveitis. Experts around the world are trying to understand this heterogeneous pathology of the visual organ, in a short time, which can lead to a sharp decrease in visual acuity, the development of severe complications and further disability. The number of patients with inflammation of the vascular tract is growing rapidly every year, the age is younger. The clinical picture of this pathology has changed slightly. Often began to manifest itself in two radically different directions. It proceeds as a sluggish form or vice versa manifests itself more aggressively with the rapid development of clinical manifestations in a short time. Currently, there is evidence of endogenous causes of uveitis.The article provides a review of the literature summarizing modern views on the problem of autoimmune uveitis. New factors affecting the etiology, pathogenesis of the disease, some aspects of therapy are considered. In addition, the main experimental models of autoimmune diseases of the vascular tract of the eye are analyzed.
Modern Methodological Approaches to the Correction of Astenopia in Patients with Visual-Intensive Work
Authors: Ovechkin I. G. , Belikova E. I. , Kozhukhov A. A. , Pozharitskii M. D. , Yudin V. E. , Budko A. A. , Shakula A. V.
Published: March 2019

The authors consider presented in the literature tested new approaches to diagnosis, prevention and correction of symptoms of asthenopia in persons visually-intense work related to theoretical aspects of asthenopia in fact, the selection of spectacle correction and application of a multidisciplinary approach. Determines the pattern of allocation in the traditional classification of asthenopia (accommodative, muscular, sensory) classification criterion is the presence or absence of phenomena of psychological maladjustment. Along with this, it is established that the astigmatic component correction of complex myopic astigmatism, it is advisable to perform in the range of 60–75 % of the required (according to cycloplegics examination of refraction). At the same time, the level of visual performance (in the most difficult conditions of presentation of test information of the type “choice of signal from several — evaluation of the signal — response ratio”) with incomplete (60–75 %) correction by 12.7–20.4 % (p < 0.05) is higher than with partial (75–85 %) and complete, taking into account minor differences in the achieved visual acuity (0.04–0.08, p > 0.05). In addition, the practical expediency of applying a multidisciplinary approach to the correction of asthenopia, based on the complex effects of specific and non-specific methods of stimulation of vision. It was found that the combined use of multidirectional technologies of physical impact (low-energy laser radiation, cranial osteopathic effects and special training of the cervical-thoracic spine) provides effective correction of accommodation disorders, which is confirmed by a pronounced, statistically significant positive dynamics of clinical and functional, ophthalmic-ergonomic and subjective indicators of the visual system after a course of therapeutic and restorative measures.
Korelasi antara kadar procalcitonin dengan serum transaminase pada pasien sepsis: sebuah studi pendahuluan
Authors: Kuswoyo Nur Hadi , Natadidjaja Ronald Irwanto
Published: March 2019

LATAR BELAKANGSepsis merupakan suatu respon sistemik terhadap infeksi. Sepsis masih merupakan penyebab kematian utama pada kasus kritis di berbagai penjuru dunia. Central of Disease Control (CDC) pada tahun 2016 mencatat sedikitnya 1.7 juta orang dewasa mengalami sepsis per tahunnya, dengan angka kematian mencapai rata rata 270.000 orang per tahun di Ameriksa Serikat. Procalcitonin (PCT) merupakan pemeriksaan baku emas pada kasus sepsis bakterial. Kejadian sepsis akan menyebabkan terjadinya gagal multi-organ, tak terkecuali terjadi gagal hati. Penelitian ini merupakan sebuah studi pendahuluan, yang mencoba untuk melihat korelasi antara peningkatan PCT dengan peningkatan serum transaminase pada pasien-pasien yang didiagnosis sepsis.

METODEPenelitian ini merupakan prelimanary study, bersifat analitik observasional dengan jumlah sampel sebesar 36 subyek, dan rancangan penelitian potong lintang di ruang ICU sebuah rumah sakit di Jawa Barat. Pada penelitian ini reduksi perancu dilakukan melalui kriteria inklusi-eksklusi, dilakukan uji korelasi Spearman setelah terlebih dahulu dilakukan uji normalitas.

HASILData yang diperoleh rerata usia subjek penelitian adalah 47.5 ± 3.57 tahun. Hasil kadar serum transaminase (SGPT) pada pasien sepsis menunjukkan rata-rata 60.4167±1.65/mm3. Rata-rata kadar procalcitonin pada pasien sepsis adalah 6.5083±0.78 ng/ml. Koefisien korelasi yang didapat pada penelitian ini antara kadar serum transaminase PCT dengan SGPT adalah r = 0.812 (p=0.000).

KESIMPULANPenelitian ini merupakan studi pendahuluan yang mungkin bisa memberikan suatu indikasi bahwa pada sepsis awal, sebenarnya sudah mulai terjadi disfungsi hati, dan dari penelitian ini terdapat korelasi yang signifikan antara peningkatan kadar PCT dengan SGPT.
About Algebraic Program Models with Procedures
Authors: Podlovchenko R. I. , Molchanov A. E.
Published: March 2019

Algebraic program models with procedures are designed to analyze program semantic properties on their models called program schemes. The concepts that give foundation to the theory of such models are stated along with a description of their implementation. The key point of the theory is the equivalence of program schemes that belong to a particular model. A class of special algebraic models with procedures, called gateway models, is studied. Necessary and sufficient conditions of the equivalence problem decidability in such models are proposed.
Concurrency Control in the Problem of Automatic Substitution of the Dataflow Network Agent on Smart-M3 Platform and in the Internet of Things
Authors: Balandin S. I. , Vasilev A. M. , Kozhemyakin N. I. , Laure D. A. , Paramonov I. V.
Published: March 2019

The paper describes implementation of dataflow networks based on Smart-M3 platform for use cases related to the Internet of Things. The mechanism for automatic substitution of computational agents created on top of Smart-M3 platform is described. The paper reviews concurrency issues of the developed solution regarding Smart-M3 platform, as well as in the broader context of the Internet of Things.
Formation of a Warped Nanomodular Surface Under Ion Bombardment. A Nanoscale Model of Surface Erosion
Authors: Kulikov D. A. , Rudy A. S.
Published: March 2019

A nanoscale model of surface erosion, simulating the process of surface shaping under ion bombardment is considered. The possibility of a ripple topography is demonstrated by means of bifurcations theory methods for dynamical systems with an infinite dimensional space of initial data. In particular, we use the normal form of Poincare–Dulak.
Polyhedral Graphs of GRAPH PARTITIONING and COMPLETE BIPARTITE SUBGRAPH Problems
Authors: Antonov A. I. , Bondarenko V. A.
Published: March 2019

We provide an effective description of graphs of polyhedra for GRAPH PARTITIONING and COMPLETE BIPARTITE SUBGRAPH problems. We establish the fact, that the clique number for each of this problems increases exponentially with the dimension of the space.
Deductive Verification of the Sliding Window Protocol
Authors: Chkliaev D. A. , Nepomniaschy V. A.
Published: March 2019

We consider the well-known Sliding Window Protocol which provides reliable and efficient transmission of data over unreliable channels. A formal proof of correctness for this protocol faces substantial difficulties caused by a high degree of parallelism which creates a significant potential for errors. Here we consider a version of the protocol that is based on selective repeat of frames. The specification of the protocol by a state machine and its safety property are represented in the language of the verification system PVS. Using the PVS system, we give an interactive proof of this property of the Sliding Window Protocol.
Deformations of Planar Equilateral Polygons with a Constant Index
Authors: Zaputryaeva E. S.
Published: March 2019

A carpenter’s rule problem is considered for the case of a self-intersecting planar polygon with additional restriction: the index (turning number) of the polygon should be preserved during deformation. We present a solution for equilateral polygons and state a problem for general ones.
Dimensional Characteristics of Diffusion Chaos
Authors: Glyzin S. D.
Published: March 2019

The phenomenon of multimode diffusion chaos is considered. For a number of examples it is shown that the Lyapunov dimension of the attractor of a distributed dynamical system increases as the diffusion coefficient tends to 0.
Asymptotics of the Solution of Bisingular Problem for a System of Linear Parabolic Equations. I
Authors: Butuzova M. V.
Published: March 2019

Given a bisingular parabolic problem for a system of linear parabolic equations, we construct an asymptotics for the solution of any order with respect to a small parameter, without using the joining procedure for asymptotic expansions.
Relaxation Oscillations in a System with Delays Modeling the Predator-Prey Problem
Authors: Kaschenko S. A.
Published: March 2019

A new asymptotic method for investigating complex relaxation oscillations of a system with delay was offered. Applying it, we can reduce the problem of predator-prey system dynamics to problem of one-dimensional maps analysis. Some conclusions of biological nature based on the asymptotic analysis were made.
The Construction of an Universal Linearized Control Flow Graph for Static Code Analysis of Algorithms
Authors: Bitner V. A. , Zaborovsky N. V.
Published: March 2019

This paper presents the description of a possible way to build the universal linearized control flow graph which is supposed to be architecture-independent and applicable to the description of any high level language programs. The practical usefulness of the graph considered is the existence of the fast and optimal search of the unique execution paths that is valuable in the methods of static code analysis of algorithms for race condition search. Optimizing compiler CLANG&LLVM is used as a technical tool for building a linearized control flow graph. The analysis of LLVM compiler procedural optimizations is carried out in the article. Transformations of intermediate representation of those optimizations result in reduction of the number of instructions responsible for conditional or unconditional branches in the code as well as the elimination or simplification of the whole loops and conditional constructions. The results of the analysis performed in the paper allowed revealing the most effective optimizations line of the LLVM compiler, which leads to a significant linearization of the control flow graph. That fact was demonstrated by the example code of the Peterson mutual execution algorithm for 2 threads.
Asymmetric Interaction of a Pair FitzHugh–Nagumo Oscillators
Authors: Marushkina E. A.
Published: March 2019

A pair of diffusion connected FitzHugh–Nagumo oscillators with an asymmetric interaction are considered. The problem is investigated in the close to critical case, where the matrix of the linear part of the system has a pair of purely imaginary eigenvalues. The normal form is constructed and its coefficients are determined depending on the initial parameters. The source system may be in two different situations: stable singlefrequency oscillations with two different frequencies coexist or a single-frequency mode branches from the equilibrium. The obtained asymptotic results are supplemented by the numerical analysis.
On Estimation of an Average Time Profit in Probabilistic Environmental and Economic Models
Authors: Rodina Lyudmila I. , Tyuteev Ilya I.
Published: March 2019

We consider environmental-economical models of optimal harvesting, given by the differential equations with impulse action, which depend on random parameters. We assume, that lengths of intervals θkbetween the moments of impulses τkare random variables and the sizes of impulse influence depend on random parameters vk, k = 1, 2, . . . One example of such objects is an equation with impulses, modelling dynamics of the population subject to harvesting. In the absence of harvesting, the population development is described by the differential equation ˙x = g(x) and in time moments τk some random share of resource vk, k = 1, 2, . . . is taken from population. We can control gathering process so that to stop harvesting when its share will appear big enough to keep possible biggest the rest of a resource to increase the size of the following gathering. Let the equation ˙x = g(x) have an asymptotic stable solution ϕ(t) ≡ K and the interval (K1, K2) is the attraction area of the given solution (here 0 ≤ K1< K < K2). We construct the control u = (u1, . . . , uk, . . .), limiting a share of harvesting resource at each moment of time τk, so that the quantity of the remained resource, since some moment τk0 , would be not less than the given value x ∈ (K1, K). For any x ∈ (K1, K) the estimations of average time profit, valid with probability one, are received. It is shown, that there is a unique x∗∈ (K1, K), at which the lower estimation reaches the greatest value. Thus, we described the way of population control at which the value of average time profit can be lower estimated with probability 1 by the greatest number whenever possible.
Replication timing in Drosophila and its peculiarities in polytene chromosomes
Authors: Kolesnikova T. D. , Antonenko O. V. , Makunin I. V.
Published: March 2019

Drosophila melanogaster is one of the popular model organisms in DNA replication studies. Since the 1960s, DNA replication of polytene chromosomes has been extensively studied by cytological methods. In the recent two decades, the progress in our understanding of DNA replication was associated with new techniques. Use of fluorescent dyes increased the resolution of cytological methods significantly. High-throughput methods allowed analysis of DNA replication on a genome scale, as well as its correlation with chromatin structure and gene activi ty. Precise mapping of the cytological structures of polytene chromosomes to the genome assembly allowed comparison of replication between polytene chromosomes and chromosomes of diploid cells. New features of replication characteristic for D. melanogaster were described for both diploid and polytene chromosomes. Comparison of genomic replication profiles revealed a significant similarity between Drosophila and other well-studi ed eukaryotic species, such as human. Early replication is often confined to intensely transcribed gene-dense regions characterized by multiple replication initiation sites. Features of DNA replication in Drosophila might be explained by a compact genome. The organization of replication in polytene chromosomes has much in common with the organization of replication in chromosomes in diploid cells. The most important feature of replication in polytene chromosomes is its low rate and the dependence of S-phase duration on many factors: external and internal, local and global. The speed of replication forks in D. melanogaster polytene chromosomes is affected by SUUR and Rif1 proteins. It is not known yet how universal the mechanisms associated with these factors are, but their study is very promising.
The role of SAGA in the transcription and export of mRNA
Authors: Nabirochkina E. N. , Kurshakova M. M. , Georgieva S. G. , Kopytova D. V.
Published: March 2019

SAGA/TFTC, which is a histone acetyltransferase complex, plays an important role in the regulation of transcription. We have identified that the metazoan TFTC/STAGA complexes had histone H2A and H2B deubiquitinase activity that is carried out by a DUBm (deubiquitination module). We studied the DUBm of SAGA in Drosophila melanogaster and identified Drosophila homologs of yeast DUBm components. Two subunits of DUBm (Sus1/ENY2 and Sgf11) were shown to have functions separate from DUBm function. Thus, Sus1/ENY2 was shown to be present in several different complexes. Sgf11 was found to be associated with the cap-binding complex (CBC) and recruited onto growing messenger ribonucleic acid (mRNA). Also, we have shown that Sgf11 interacted with the TREX-2/AMEX mRNA export complex and was essential for mRNA export from the nucleus. Immunostaining of the polytene chromosomes of Drosophila larvae revealed that Sgf11 is present at the sites of localization of snRNA genes. It was also found in immunostaining experiments that dPbp45, the subunit of the PBP complex, the key player in the snRNA transcription process, is associated not only with the snRNA gene localization sites, but with other sites of active transcription by PolII. We also revealed that Sgf11 was present at many active transcription sites in interbands and puffs on polytene chromosomes, Sgf11 was localized at all Brf1 (the component of the RNA polymerase III basal transcription complex) sites. We concluded that SAGA coactivated transcription of both the PolII and PolIII-dependent snRNA genes.
An Analysis of Non-Conventionally Indirect Request in Haikyuu!! (1st Season) Anime
Authors: Sumarti Siti , Widodo Pratomo
Published: March 2019

This research is aimed to find and to explain the implicit meaning in non-conventionally indirect request in Haikyuu!! (1st Season) anime and the reason the speaker request in non-conventionally indirect way which found in Haikyuu!! (1st Season) anime. This research is in descriptive qualitative research. The data were taken from Haikyuu!! (1st Season) anime, specifically, the dialogue from the Haikyuu!! (1st Season) anime that contains non-conventionally indirect request. The subject of the research is Haikyuu!! (1st Season) anime and the object is non-conventionally indirect request. In collecting the data, the researcher uses teknik catat or noting technique. In analyzing data, the researcher uses metode padan specifically in metode padan pragmatics. The analysis of the research shows that Haikyuu!! (1st Season) anime, from 25 episodes, has four forms of non-conventionally indirect request in Haikyuu!! (1st Season) anime, they are: imperatives, interrogatives, negative interrogatives, and declaratives.
ANÁLISE SWOT ACERCA DA PRODUÇÃO AGRÍCOLA NO VALE DO SÃO FRANCISCO: O CASO DO CUCUMIS MELO L.
Authors: Souza Santos Pedro Vieira
Published: March 2019

O Cucumis melo L., comumente chamado de melão, é uma hortaliça produzida em diversas partes do mundo e com níveis altos de consumo, tendo grande popularidade no mundo sendo capaz de adaptar-se em regiões quentes, com períodos secos mais acentuados. Entretanto, apesar da importância econômica dessa olerícola, há uma carência de estudos recentes sobre a cultura do melão na região do Vale do São Francisco. Assim, este trabalho, teve como objetivo, identificar os pontos fortes, pontos fracos, as ameaças e oportunidades referentes à produção de melão no Vale do São Francisco, a partir da aplicação da análise SWOT. Do estudo nota-se que existem aspectos no ramo estudado que devem ser observados no sentido de aprimorar o seu desempenho. Destacam-se o potencial de produção, qualidade e quantidade adequada e os sistemas de manejo da cultura, apresentando fortes tendências de crescimento em função do consumo interno e das exportações. Por outro lado, questões relacionadas aos custos de produção, pragas e doenças, interferem significativamente na rentabilidade produtiva. Portanto, através do estudo feito foi possível analisar de forma mais precisa o ambiente interno e externo em que os olericultores encontram-se inseridos.
GAMIFICAÇÃO COMO ESTRATÉGIA DE ENSINO
Authors: Michels Tatiana Aparecida , Padula Paz Daiane , Saldanha Ferreira Aline Maiara
Published: March 2019

O comportamento e contexto de jogos em outras situações deram origem ao termo gamification, conhecido como gamificação ou ludificação em português. Usado inicialmente como estratégia de marketing este recurso passou a ser utilizado em diversas áreas do conhecimento, entre elas a educação. Seu uso tem sido considerado positivo em práticas pedagógicas pois, de forma lúdica, despertam interesse dos estudantes e pode ajudar a desenvolver certas habilidades além de colaborar para autonomia através de atividades diversas. Os elementos de jogos como recompensas, pontuação e desafios tem ganhado cada vez mais espaço e possibilidades, mostrando-se eficiente para aproximar estudantes e melhorar seu desempenho. Considerando-se o contexto atual das instituições de ensino, as quais estão repletas de nativos digitais que fazem uso constante das tecnologias digitais, entende-se que é essencial promover atividades adequadas ao seu perfil, e a gamificação é uma boa alternativa. Dessa forma, este artigo apresenta conceitos de gamificação e sua importância, além de exemplos de aplicabilidade como estratégia de ensino. Para tanto, realizou-se pesquisa bibliográfica sobre esta temática e buscou-se situações de uso para a construção do conhecimento. Conclui-se que a gamificação, apesar de ser um conceito relativamente novo, e de aplicabilidade ainda reduzida nos espaços escolares, é uma estratégia muito positiva pois desperta o interesse e atenção dos aprendizes, proporcionando engajamento no ensino. Palavras-chave: Gamificação. Tecnologias. Ensino.
CONECTIVISMO: APRENDENDO A PARTIR DAS CONEXÕES
Authors: Pilonetto Ivânia Almeida , Paz Daiane Padula , Rodrigues Lilian
Published: March 2019

Com a popularização da internet, nos anos 90, emergiram outras necessidades sociais. A velocidade do avanço das tecnologias redimensionou a forma de agir desta época impactou a sociedade contemporânea. Com a pós modernidade a sociedade da informação é essencialmente digital e comunicacional. Estabelecer conexões, processar, armazenar e disseminar informações são tarefas desta nova forma de agir e que, consequentemente, altera-se a forma de como se aprende. A aprendizagem não se restringe a compartimentar ou armazenar conhecimento, na verdade, vai muito além e significa aplicar o conhecimento na prática real de vivências. Estamos em uma sociedade hiperconectada e há uma constante transformação de dados e de interação em uma sociedade em rede, a qual redimensiona nossa forma de agir e de aprender. Considerando este contexto, esta pesquisa apresenta a teoria de aprendizagem do conectivismo e sua relação com as tecnologias, argumentando sobre o papel das conexões neurais, humanas, físicas e virtuais para a aquisição de informações e para a construção do conhecimento. Discorre sobre a aplicabilidade desta teoria na educação e sua influência na escola e na sociedade, bem como para a formação do protagonismo discente. Apontando ainda para alguns entraves e possibilidades da aplicação dessa nova teoria no sistema educacional brasileiro.
LEARNING ANALYTICS: O USO DE FERRAMENTAS TECNOLÓGICAS NO PROCESSO DE ENSINO E APRENDIZAGEM
Authors: Gomes Marília Beatriz dos Santos , Sandeski Michele de Souza , Matiello Cleidiane , Paz Daiane Padula
Published: March 2019

A presente pesquisa foi desenvolvida nas aulas de Tecnologias e Novas formas de Ensino, ministradas no curso de Especialização em Linguagens Híbridas e Educação, do Instituto Federal do Paraná – Campus Palmas. Sabe-se que com os avanços tecnológicos, especificamente com a integração das Tecnologias da Informação e Comunicação (TICs) na educação, os estabelecimentos educacionais estão repensando e buscando novas metodologias ativas e ferramentas tecnológicas com o intuito de fortalecer e de dinamizar o processo de ensino e aprendizagem. Cada vez mais se podem perceber tais mudanças, principalmente nas universidades, que estão empregando com maior frequência recursos midiáticos, como o uso de plataformas online, além de optarem por novas formas de ensino como o semipresencial/ híbrido e o ensino a distância. Aqui, propomos analisar por meio do levantamento teórico, uma, entre as diversas ferramentas e tecnologias educacionais que vêm a contribuir e auxiliar tanto professores, quanto alunos durante o processo de ensino e aprendizagem, especificamente: o Learning Analytics (LA). O LA é compreendido enquanto ferramenta tecnológica de coleta e análise de dados provenientes dos Ambientes Virtuais de Aprendizagem, e que, também, proporciona uma experiência online de aprendizagem personalizada. Vale ressaltar que o Learning Analytics vem conquistando espaço em instituições de ensino físicas, e não apenas nos espaços virtuais de ensino. Isto ocorre devido à fomentação do uso de ferramentas digitais na educação e na busca de aprimoramento nos processos de ensino e aprendizagem.
ARTE CONTEMPORÂNEA E FEMINISMO: Uma proposta de ensino híbrido para o ensino médio
Authors: Ramos da Silva Angela Maria , Biziak Jacob dos Santos
Published: March 2019

Resumo: A seguinte proposta intitulada “Arte contemporânea e feminismo: uma proposta de ensino híbrido para o ensino médio” surgiu a partir da disciplina de “Teorias Pós-estruturalistas sobre Hibridismos da Linguagem” ministrada pelo Professor Doutor Jacob dos Santos Biziak, no Curso de Especialização em Linguagens Hibridas e Educação, do Instituto Federal do Paraná, campus Palmas. A escolha do tema “Arte contemporânea e Feminismo” manifestou-se com base nos estudos realizados pela autora, que desde a graduação vem pesquisando sobre o tema feminismo, arte contemporânea e educação. Assim, desenvolveu-se este estudo que tem como objetivo geral a elaboração de um Plano de Aula para ser aplicado com alunos do Ensino Médio, na Disciplina de Arte. O encaminhamento metodológico será realizado a partir da abordagem do conteúdo utilizando a Proposta Triangular, idealizada pela pesquisadora Ana Mae Barbosa, o qual manifesta a aprendizagem em arte com base na Contextualização do tema, sentir/perceber e fazer artístico, e, a partir da apresentação do tema com recursos tecnológicos e audiovisuais que fazem parte do contexto do discente. Desta forma, o trabalho se encontra em fase de desenvolvimento do plano de aula, através do levantamento e estudo dos referenciais teóricos, entretanto, a autora, se mantem confiante com o desenrolar da pesquisa e apreensiva com os resultados da prática educacional.Palavras-chave: Arte educação. Arte contemporânea. Feminismo. Ensino híbrido.
OBJETIVOS DO DESENVOLVIMENTO SUSTENTÁVEL: UMA ANÁLISE DO ODS 6 PARA OS PAÍSES DO MERCOSUL
Authors: Da Silva Creir , Pereira Máriam Trierveiler
Published: March 2019

Com base nos inimigos históricos da humanidade foi publicada, em 2000, a Declaração do Milênio das Nações Unidas, que estabeleceu compromissos mínimos pela promoção da dignidade humana em todo o planeta, consolidada nos Objetivos de Desenvolvimento do Milênio (ODM). Em 2015, foi definida a agenda pós-2015 para o Desenvolvimento Sustentável, tendo em vista a continuidade das ações para o avanço em todos os níveis. Os dezessete Objetivos de Desenvolvimento Sustentável (ODS) mesclam de forma equilibrada, as três dimensões do desenvolvimento sustentável. Destes, o ODS-6 busca assegurar a disponibilidade e gestão sustentável e saneamento para todos. Este trabalho tem como objetivo realizar um estudo dos indicadores que compõem o ODS-6 para os países do Mercosul. Os países integrantes são: Argentina, Bolívia, Brasil, Chile, Colômbia, Equador, Guiana, Paraguai, Peru, Suriname, Uruguai e Venezuela.  As informações foram coletadas na base de dados do relatório de 2017 do “Índice e Painéis dos Objetivos de Desenvolvimento Sustentável” e foram realizadas análises dos dados que compõem o ODS-6. Os resultados foram classificados em: pleno atendimento, situação regular e atendimento precário, conforme a metodologia adotada. Em relação ao acesso a fontes melhoradas de água, apenas Argentina, Chile e Uruguai estão com pleno atendimento. Com relação ao acesso a instalações sanitárias melhoradas os países que ainda estão em atendimento precário são Bolívia e Peru. Todos os países desse estudo encontram-se em situação precária quanto à captação de água doce. Considerando que os ODM já tinham como metas o acesso à água e ao saneamento desde 2000, verifica-se que, dos países estudados, muitos se encontram em situação alarmante quanto ao cumprimento integral do ODS-6, sobretudo Bolívia e Peru, que apresentam situação precária nos três indicadores. Contudo, todos os países do Mercosul têm grandes possibilidades de atingirem as metas até 2030.
Utilizing the time delayed PPF controller to suppress vibrations of a nonlinear system containing real power exponents in damping and restoring forces
Authors: Abdelhafez H. M.
Published: March 2019

The time delayed Positive Position Feedback (PPF) controller is utilized to suppress the primary resonance of vibrations of an excited base oscillator by real power exponents of the restoring and damping forces. Multiple scales method is conducted to get the frequency response equations. The stability of the system is studied by using the Lyapunov first method. The influences of system parameters and time delay on the system response are investigated to avoid the jump phenomenon for better system performance. Time margin is deduced for most possible values of controller gain. Analytic results are verified by numerical integration of the original system equations.
Vibroacoustic measurements and analysis of blasting works
Authors: Pyra Józef , Kłaczyński Maciej
Published: March 2019

Blasting works cause short-term high-energy shock waves - acoustic, air (airblast) and paraseismic. The duration of the event can be up to 2-3 seconds, while the rise time to the peak value is directly related to the delay between the individual explosive material (EM) and the firing sequence and ranges from a few to several milliseconds. Their propagation in the environment can affect people, animals and construction structures located not only in the close but also further distance from their source. If EM is placed on the surface of the earth during the detonation, the shock wave spreads evenly in all directions in the half-space, and when the detonation follows in rock, the wave usually travels in one direction and is accompanied by a paraseismic wave. However, the sound heard when detonating is part of the wave spectrum in the band from 20 to 20000 Hz, while the airblast itself has a frequency of less than 20 Hz. Since at some distance from the detonated EM, the parameters of the airblast are close to the parameters of the acoustic wave, the method of spreading the acoustic wave depends to a great extent on atmospheric conditions, i.e. density, temperature and humidity of the air, and from wind speed and its direction. To get to know the essence of the phenomenon of the impact of blasting works, measurements are carried out considering the propagation conditions, i.e. meteorological conditions as well as vibration analysis in the ground itself and on the building substructure. This paper presents the results of research carried out by the Authors in terms of the correct assessment of the impact range (acoustic, airblast, paraseismic waves) during EM detonation placed on the surface.
Mathematical modeling of first order process with dead time using various tuning methods for industrial applications
Authors: Shanmugam Sathish Kumar , Duraisamy Yuvaraj , Ramachandran Meenakumari , Arumugam Senthilkumar
Published: March 2019

The proposed research involves Mathematical modeling for first order process with dead time using various tuning methods for industrial applications. Different tuning methods are proposed. Proposed method selection depends on plant operating conditions and also depending upon the process dynamics. The PID controller is most widely used for industrial process control. Modeling were developed for modified internal control model [4-6] in this proposed research. The proposed work is the modeling and simulation of three different first order processes with dead time. The standard controller tuning method is used to obtain the steady state response of first order with dead time.
Optimization of palm methyl ester and its effect on fatty acid compositions and cetane number
Authors: Satya Sharath , Kolakoti Aditya , B. Naga Raju , R. Shyam Sundar , Rao Ranga
Published: March 2019

This paper proposes the Taguchi based optimization technique for the production of biodiesel from palm oil. For this purpose, L9 orthogonal array was successfully used for better yield estimation by using Minitab-18 software. Different process variables like molar ratio, catalyst concentration, reaction time and reaction temperature were studied. A predicted yield of 92.06 % was achieved by regression analysis by maintaining the process variables of molar ratio 5:1 (methanol to oil), 4 grams of catalyst concentration (NaOH), 180 minutes of reaction time and 44°C of reaction temperature. Experimentations were conducted on the same process variables and achieved a yield of 91.65 %. By this it is clear that both experimentation and regression analysis by Taguchi are in good agreement with an error of 0.41 % which may be acclaimed as experimental error. The fatty acid compositions (FAC) were also analyzed and it is found that 37.12 % saturated and 62.88 % unsaturated fatty acids present in the palm methyl ester (PME). By using the FAC of PME the Cetane number was predicted as 55.38. The predicted Cetane number from FAC tally with experimental Cetane number. The PME is characterized for different fuel properties by following the international standards. And it is concluded that catalyst concentration and reaction temperature are the important parameters which influence PME yield, Taguchi based optimization technique will helps in predicting the maximum yield with minimum number of experiments.
Green Building with Nature Concept on Lakeside Resort Design
Authors: Wasilah Wasilah , Hildayanti Andi , Hamzah Hamzah
Published: March 2019

The natural condition of Matano lake is heavily scenic includes the land, water, air, energy, and reasonably required to preserve. Exploration in the resort design with green building and design with nature concept is one of preservation effort to maximize the natural potency of the area based on the aspect of environment, socio-economics, and sociocultural. The method in the design process  involve  a green building and design with nature principles implementation in the site plan, structural design, natural energy to maintain the building thermal and natural lighting, and reuse rainwater management to optimize the resort function, green materials and prevent the residual material. The result explained the lakeside resort based on green building and design with nature  principles  increase the aesthetic potential view and environmental  sustainability of Matano lake.