bluuebunny/crossref_metadata_2025 huggingface dataset:
BIỂU HIỆN PROTEIN INTERLEUKIN-7 TÁI TỔ HỢP TRONG DÒNG TẾ BÀO THUỐC LÁ BY-2
Authors: Hoàng Nguyễn Huy , Ngọc Phạm Bích , Hà Chu Hoàng , Sơn Lê Văn
Published: December 2018

Interleukin là một nhóm các cytokine được tìm thấy đầu tiên trong các tế bào bạch cầu, đóng vai trò điều hòa đáp ứng miễn dịch. Trong đó, interleukin 7 (IL7) là một cytokine có vai trò chính trong sự tăng trưởng của các dòng tế bào B và T, đây là những dòng tế bào có chức năng quan trọng trong hệ miễn dịch của con người. Trong nghiên cứu này, chúng tôi tiến hành tổng hợp nhân tạo gen IL7 với mã di truyền được tối ưu hóa biểu hiện trong dòng tế bào thuốc lá BY-2. Chúng tôi sử dụng vector pK7WG2D.1/cal để tạo cấu trúc pK7WG2D.1/cal/IL7. Cấu trúc này được sử dụng để chuyển gen IL7 vào các dòng tế bào thuốc lá BY-2. Gen đích trong các dòng tế bào BY-2 được đánh giá bằng kỹ thuật PCR và protein tái tổ hợp được xác định bằng lai miễn dịch Western blot. Kết quả cho thấy, đã tạo được các dòng tế bào BY-2 sinh trưởng ổn định trong môi trường lỏng sau 5 lần cấy chuyển với khoảng cách mỗi lần cấy chuyển là 2 tuần. Các dòng BY-2 chuyển gen sinh trưởng ổn định và biểu hiện protein tái tổ hợp IL7 có kích thước khoảng 23 kDa. Đây là kết quả mới ở Việt Nam và trên thế giới, IL7 được biểu hiện trong dòng tế bào thuốc lá BY-2. Kết quả này mang lại tiềm năng lớn cho nghiên cứu và sản xuất protein IL7 tái tổ hợp phục vụ trong y học.
AGROBACTERIUM-MEDIATED TRANSFORMATION OF PANAX VIETNAMENSIS HA ET GRUSHV.
Authors: Nhut Duong Tan , Huy Nguyen Phuc , Huong Trinh Thi , Luan Vu Quoc , Hien Vu Thi , Tung Hoang Thanh , Cuong Do Manh , Bich Phuong Chu Thi , Ngoc Pham Bich , Trong Nguyen Dinh , Hung Nguyen Khac , Ha Chu Hoang
Published: December 2018

In recent years, the Agrobacterium-mediated genetic transformation system has become the most useful method widely used for the introduction of foreign genes into plant cells followed by regeneration of genetically improved plants. Panax vietnamensis Ha et Grushv. is a highly valued medicinal plant native to Vietnam with limited area of distribution. This report illustrates the possibilities of biotechnology for genetic transformation aimed at establishing an effective production of secondary metabolites in P. vietnamensis. In the present investigation, 0.5 cm2 leaf blades, 1 cm long leaf petioles and 0.5 cm3 callus clusters were used for the hairy root induction. Results indicated that hairy roots were induced on P. vietnamensis callus clusters co-cultivated with Agrobacterium rhizogenes strain ATCC15834 at OD600 of 0.5 with an infection time of 20 min and a supplementation of 100 mM acetosyringone. PCR amplification of the DNA isolated from the resulting hairy roots was used to confirm the presence of rol genes. Compared to in vitro rhizome cultures, hairy root cultures appear to be potential for continuous production of valuable secondary metabolites with similar saponin profiles. The protocol described in this study is simple and rapid and therefore, can be used for large-scale experiments for the rapid production of valuable compounds.
TAXONOMIC IDENTITY OF ARISAEMA CONDAOENSE (ARACEAE) BASED ON NEW MORPHOLOGICAL AND MOLECULAR DATA
Authors: Thien Van Hong , Nguyen Phi Nga , Truong Luu Hong
Published: December 2018

Arisaema condaoense V.D. Nguyen was described as a new species from Con Dao National Park, Ba Ria–Vung Tau Province, Vietnam in 2000. However, this species has been suspected of being a form of Arisaema roxburghii Kunth, a species widespread in the whole Indochina and Malay Peninsula. This was due to the original description based on dried specimens with male inflorescences only. Morphological characteristics of female inflorescences, which are of taxonomical importance to identify the species, have not been known. In June 2015, we re-sampled the plant in Con Dao National Park with both male and female inflorescences for detailed examination of morphological characteristics. Besides, the matK gene of the chloroplast genome of this species was sequenced to analyse its phylogenetic relationship with other Arisaema species. The gathered morphological and molecular data indicate that A. condaoense is certainly a distinct species, not a synonym of A. roxburghii. The noted morphological characteristics also provide key differences to distinguish A. condaoense from two other morphologically close species of sect. Fimbriata (i.e A. maxwellii from Thailand and A. pierreanum from Vietnam which also share yellow spathes and several other characteristics in common), which are supported by the molecular data. Thus, the species is endemic to Con Dao National Park in Ba Ria–Vung Tau Province, Vietnam. Furthermore, this study allows us revising the description of A. condaoense with, for the first time, supplemental key taxonomic characteristics and illustrating colourful photographs taken from the fresh materials. A key to all eight known Vietnamese species of sect. Fimbriata is also given.
INVESTIGATING THE PRODUCTION OF EXTRACELLULAR ENZYMES OF VIBRIO PARAHAEMOLYTICUS STRAINS ISOLATED IN VIETNAM
Authors: Vu Ngo Nguyen , Thu Hien Pham Thi , Minh Tien Le Nguyen , Phuc Chau Do Ngoc , Tung Hoang , Thu Hoai Nguyen Thi
Published: December 2018

Acute Hepatopancreatic Necrosis Disease (AHPND) is a widespread disease targeting cultured shrimps, which results in heavy losses in many regions around the world including Vietnam. The causative agent of the disease is Vibrio paraheamolyticus which is a Gram-negative bacterium present ubiquitously in marine environment. However, this normal floral organism once acquired a plasmid containing Pir- toxin encoding gene (AHPND plasmid) can transform into a highly toxic strain (AHPND strain) with the ability to kill a large number of cultured shrimps in a short period. To understand more on the virulence of V. parahaemolyticus, 17 different V. parahaemolyticus isolates collected from different locations in Southern Vietnam have been analyzed for the presence of AHPND plasmid using PCR method and their extracellular enzyme profile using agar- based method. Seven enzymes which are known to be important virulence factors of the bacterium were studied including caseinase, gelatinase, lecithinase, hemolysin, elastase, lipase and chitinase. Results showed that among 17 studied isolates, six were detected to have AHPND plasmid. Enzymatic activity was observed for caseinase, gelatinase and lecithinase while undetectable for others. The ability to produce these three enzymes varied among different V. parahaemolyticus isolates. Lecithinase appeared in all isolates while the presence of caseinase and gelatinase varied. This indicated that lecithinase seems to be core enzyme of V. paraheamolyticus and the extracellular enzymes do not correlate with the presence of AHPND plasmid. In conclusion, our data suggested that the virulence of Vibrio parahaemolyticus mostly depends on the presence of AHPND plasmid other than extracellular enzymes.
EVALUATING THE ANTI-BACTERIAL ACTIVITY OF MYCELIUM EXTRACT FROM DIFFERENT WOOD-DECAY-FUNGUS SPECIES COLLECTED IN SOUTHERN VIETNAM
Authors: Hoa Pham Thi , Vu Ngo Nguyen , Phuong Linh Tran Thi
Published: December 2018

The antibacterial activity of twelve different wood-decay fungal isolated in Southern Vietnam was investigated to find out the new potential antibiotics produced by macro fungi. The antibacterial activity of the collected fungal isolates was tested by three screening methods against seven different strains of bacteria: Bacillus subtilis, Enterococcus faecalis, Staphylococcus aureus, Escherichia coli, Vibrio parahaemolyticus, Vibrio cholerae, and Salmonella typhi. The screening test were performed at first with mycelium grew on surface of agar medium similar to a disc diffusion test, next by an extracellular metabolite test by flood-plate method, and finally with an intracellular metabolite test using grounded mycelium fluid. To determine the activity of metabolites produced in the mycelium, the fungal isolates were grown on culture substrates to promote mycelium formation. Antibacterial activity of the selected fungi was confirmed by disc diffusion method using crude extract of the mycelium harvested from the substrate cultures. Four fungal species identified with strong antibacterial compounds produced by their mycelium including Pycnoporus sanguineus, Flavodon flavus, Fomitopsis ostreiformis and Meripilus giganteus. Crude extract of Pycnoporus sanguineus showed the strongest antibacterial activity, with 7/7 bacterial strains inhibited. Fomitopsis ostreiformis antibacterial activity was recognized with the ability to inhibit 6/7 bacterial strains. Flavodon flavus and Meripilus giganteus showed weaker activity than other two species, with only 4/7 strains inhibited. The fungal isolates identified with antibacterial activity discovered in this study can be potential candidates for the new source of antibiotic to fight against new generations of antibiotic resistance bacteria in the future.
Tumor Size Affects Efficacy of Adjuvant Transarterial Chemoembolization in Patients with Hepatocellular Carcinoma and Microvascular Invasion
Authors: Liu Shuang , Li Hui , Guo Lei , Zhang Bo , Zhou Binghai , Zhang Wentao , Zhou Jian , Fan Jia , Ye Qinghai
Published: December 2018

Background

Patients with hepatocellular carcinoma (HCC) and microvascular invasion (mVI) have shown dismal postoperative prognosis; however, whether adjuvant transarterial chemoembolization (TACE) can improve their outcomes remains unclear.

Materials and Methods

We retrospectively identified 549 eligible patients to form the crude cohort and adopted propensity score matching method to assemble another cohort of 444 patients with similar baseline characteristics. We assessed the effects of adjuvant TACE by stratified analyses and multivariate Cox analyses in two cohorts.

Results

There was significant interaction between tumor size and adjuvant TACE with respect to overall survival (OS; p = .006 for interaction). In the matched cohort, patients who received adjuvant TACE showed higher rates of 5-year OS (72.4% vs. 50.9%, p = .005) and 5-year recurrence-free survival (50.5% vs. 36.4%, p = .003) in the tumor ≤5 cm subgroup, but not in the tumor >5 cm subgroup (32.3% vs. 24.9%, p = .350 and 18.8% vs. 19.7%, p = .180). The independent protective role of adjuvant TACE on OS was observed in patients with tumor ≤5 cm (adjusted odds ratio [OR] = 0.59, 95% confidence interval [CI] 0.36–0.97) but not in patients with tumor >5 cm (adjusted OR = 1.17, 95% CI 0.84–1.62). The effects of adjuvant TACE did not change materially while the analysis was performed in the crude cohort.

Conclusion

For patients with HCC and mVI, adjuvant TACE was associated with improved outcomes, but not for those with tumor >5 cm, according to the current protocol.

Implications for Practice

The outcomes of patients with hepatocellular carcinoma and microvascular invasion who received adjuvant transarterial chemoembolization were inconsistent in this study. According to the current protocol, adjuvant transarterial chemoembolization was associated with improved prognosis in patients with microvascular invasion, except for those with tumor >5 cm. Multivariate Cox models confirmed adjuvant transarterial chemoembolization was an independent protective factor in the tumor ≤5 cm subgroup but not in the tumor >5 cm subgroup.
Patient-Reported Toxicities During Chemotherapy Regimens in Current Clinical Practice for Early Breast Cancer
Authors: Nyrop Kirsten A. , Deal Allison M. , Shachar Shlomit S. , Basch Ethan , Reeve Bryce B. , Choi Seul Ki , Lee Jordan T. , Wood William A. , Anders Carey K. , Carey Lisa A. , Dees Elizabeth C. , Jolly Trevor A. , Reeder-Hayes Katherine E. , Kimmick Gretchen G. , Karuturi Meghan S. , Reinbolt Raquel E. , Speca JoEllen C. , Muss Hyman B.
Published: December 2018

Background

This study explores the incidence of patient-reported major toxicity—symptoms rated “moderate,” “severe,” or “very severe”—for chemotherapy regimens commonly used in early breast cancer.

Patients and Methods

Female patients aged 21 years or older completed a validated Patient-Reported Symptom Monitoring instrument and rated 17 symptoms throughout adjuvant or neoadjuvant chemotherapy. Fisher's exact tests compared differences in percentages in symptom ratings, and general linear regression was used to model the incidence of patient-reported major toxicity.

Results

In 152 patients, the mean age was 54 years (range, 24–77), and 112 (74%) were white; 51% received an anthracycline-based regimen. The proportion of patients rating fatigue, constipation, myalgia, diarrhea, nausea, peripheral neuropathy, and swelling of arms or legs as a major toxicity at any time during chemotherapy varied significantly among four chemotherapy regimens (p < .05). The mean (SD) number of symptoms rated major toxicities was 6.3 (3.6) for anthracycline-based and 4.4 (3.5) for non-anthracycline-based regimens (p = .001; possible range, 0–17 symptoms). Baseline higher body mass index (p = .03), patient-reported Karnofsky performance status ≤80 (p = .0003), and anthracycline-based regimens (p = .0003) were associated with greater total number of symptoms rated major toxicities (alternative model: chemotherapy duration, p < .0001). Twenty-six percent of dose reductions (26 of 40), 75% of hospitalizations (15 of 20), and 94% of treatment discontinuations (15 of 16) were in anthracycline-based regimens.

Conclusion

Capturing multiple toxicity outcomes throughout chemotherapy enables oncologists and patients to understand the range of side effects as they discuss treatment efficacies. Continuous symptom monitoring may aid in the timely development of interventions that minimize toxicity and improve outcomes.
Occupational Therapy in the bereavement process: A meta-synthesis
Authors: Ferreira Dahdah Daniel , Vitale Torkomian Joaquim Regina Helena
Published: December 2018

INTRODUCTION: Bereavement is a complex process characterised by a state of grief and suffering, which impacts the health and well-being of the bereaved, and extends to their occupational performance. Thus, occupation can be understood to be central in the expression of bereavement after the death of a loved one as it mediates identity formation, interpersonal relationships, a sense of belonging, and future perspectives PURPOSE: To review English and Portuguese literature and identify how occupational therapists perceive and/or intervene in the bereavement process METHOD: A meta-synthesis was conducted by database search and article analysis RESULTS AND DISCUSSION: Eight qualitative style articles were analysed. From these, three categories were derived from the content analysis: 1) Relationship between study participants and the deceased; 2) Occupational repercussions of bereavement; and 3) Occupation as a means to an end in the therapy process of the bereaved. CONCLUSIONS: Although the need for studies of the bereavement process and its implications for occupations is urgent, this study points out that occupations can be predictors of understanding the elaboration process through occupational engagement and that they also act as a potential resource to construct meaning about the death of the loved one Key words: Occupational therapy, bereavement, grief, mourning, attitude to death
Города и миграционные исследования
Authors: Варшавер Евгений Александрович , Рочева Анна Леонидовна
Published: December 2018

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От редакторов
Authors: Майорова Ксения Сергеевна
Published: December 2018

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Theory of mind abilities and its relationship with clinical features in euthymic bipolar patients
Authors: ATEŞ BUDAK Elif , KÜÇÜKGÖNCÜ Suat , BEŞTEPE Engin Emrem
Published: December 2018

Purpose: The term of ‘Theory of mind’ (ToM), is the ability
to understand one’s own others’ mental states, is an important capacity for
social cognition and there is increasing data that theory of mind is
compromised in bipolar patients even in euthymic periods. The aim of this study
was to investigate theory of mind deficits in euthymic bipolar disorder
patients and its relation to the clinical features. Materials and method:Fifty two euthymic patients with bipolar I disorder
according to DSM IV-TR and 60 matched healthy control subjects were involved
in this study. ToM was assessed by Reading the Mind in the Eyes test and the
Dokuz Eylül Theory of Mind Scale.

Results: The patient group had significantly lower
performance on both of the ToM tests. We observed significant correlation
between age of onset, the number of hospitalizations, the number of manic/mixed
episodes and theory of mind performance. 

Conclusion: The result we showed is that ToM is impaired in
euthymic bipolar I patients, which is consistent with the studies suggesting
that ToM might be a trait marker for bipolar disorder.
High-density Mapping  Toy or Tool?
Authors: Pürerfellner Helmut ,   Department of Cardiology, Ordensklinikum Linz GmbH Elisabethinen, Fadingerstraße, Austria
Published: December 2018

High-density (HD) mapping with new multipolar HD-mapping catheters has changed the way we look at cardiac arrhythmias, especially atrial tachycardia and ventricular arrhythmia. Some small studies have shown a good feasibility and promising results. Scar definition with small and closely spaced electrodes still remains unstandardised. Randomised controlled studies are needed to prove the potential benefits of this new technology.
Hipertansiyon Hastalarının Özellikleri ile Sürekli Kaygı ve Baş Etme Becerileri Arasındaki İlişki
Authors: Uysal Zekai , Aslan Harun
Published: December 2018

Amaç: Bu çalışmanın amacı hipertansiyon hastalarının sürekli kaygı düzeylerini, kullandıkları başa çıkma stratejilerini, sosyo-demografik özelliklerini, kaygı ve başa çıkma stratejileri arasındaki ilişkileri araştırmak ve tanımlamaktır. Gereç ve Yöntem:Çalışmada kaygı düzeyini ölçmek için 20 maddeden oluşan Sürekli Kaygı Ölçeği (STAI TX-2) ve başa çıkma stratejilerini ölçmek için (Carver ve ark. 1989) tarafından geliştirilen ve 28 maddeden oluşan Baş Etme (KF) ölçeğinden yararlanılmıştır. Bu çalışma, kesitsel tasarım ve kolayda örnekleme yöntemlerinin kullanıldığı bir tarama çalışmasıdır.Bulgular:Çalışmanın örneklemi Ankara Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi’nde hizmet alan hipertansiyon tanısı almış 147 kişi oluşturmaktadır. Çalışmaya katılan katılımcıların %57.1’i kadın katılımcıdır. Katılımcıların yaş ortalamaları 61.16±10.52 (ortalama±s.sapma) olarak elde edilmiştir. Katılımcıların %95.9’ u (n= 141) sürekli kaygı eşiği olan 42 puanı aşmıştır. Katılımcıların en çok kullandıkları problem odaklı başa çıkma stratejileri; din ve kabullenme stratejileriyken en çok kullanılan duygu odaklı başa çıkma stratejileri ise; dikkatini başka yöne yöneltme ve kendini suçlama stratejileridir.Sonuç:Sosyo-demografik ve sağlığa ilişkin özellikler, anksiyete ve başa çıkma stratejileri arasında önemli korelasyonlar bulunmuştur. Bulgular, hipertansiyonun psikososyal refah üzerindeki etkisini değerlendirirken bireysel baş etme stratejilerini dikkate almanın önemine işaret etmektedir
Revitalisasi Kearifan Lokal Aceh: Gagasan Islam dan Budaya dalam Menyelesaikan Konflik di Masyarakat
Authors: Riezal Chaerol , Joebagio Hermanu , Susanto Susanto
Published: December 2018

This article answers the question of how the form of revitalization of local wisdom in Aceh culture as the capital to resolve conflicts in the community. The important thing that will support this article is how Islamic ideas and Acehnese culture combine into one formulated from within, at least strengthening traditional institutions as the basis for managing Aceh culture is an important discourse to measure indicators of the ongoing settlement of Islamic conflicts. The results indicate that the re-actualization of Aceh culture which had been submerged by the conflict and tsunami, has now been revived especially on the social bases that were lost and even blurred. When there was a conflict in the Acehnese community, the mechanism for resolving conflicts was carried out using the Acehnese cultural approach known as Di’et, Sayam, Suloh, Peusijuek and Peumat Jaroe, involving Aceh traditional institutions at the village level, such as the geuchik (village headman), teungku imum and traditional leaders. This local wisdom in the discourse of the Aceh Government has reached the implementation of policies by making regional regulations through qanun to revitalize Aceh’s local wisdom by reviving some traditional institutions that have not been functioning.
UMA ANÁLISE DA TEORIA DA JUSTIÇA EM ARISTÓTELES PRESENTE NA ÉTICA A NICÔMACO (LIVRO V)
Authors: Vale da Silva Maria Domingas
Published: December 2018

AN ANALYSIS OF THE THEORY OF JUSTICE IN ARISTÓTELES PRESENT IN THE NICOMACHEAN ETHICS (BOOK V)EL ANÁLISIS DE LA TEORÍA DE LA JUSTICIA EN ARISTÓTELES PRESENTE EN LA ÉTICA LA NICÓMACO (LIBRO V)O presente artigo faz uma análise do tema da justiça presente no Livro V da obra “Ética a Nicômaco” do filósofo grego Aristóteles. Nesta, leva em conta os diversos temas atinentes ao termo conforme apresenta o próprio filósofo. Por conta disso, inicia alocando a justiça enquanto virtude por excelência. Posteriormente, passa a analisar a significação e posterior distinção entre justiça total e justiça particular (nesta última, distingue justiça distributiva de justiça corretiva), justiça política e justiça doméstica, justiça natural e justiça legal, a designação de justiça como equidade, a relação entre amizade e justiça e, por fim, a consideração do juiz como justiça animada.Palavras-chave: Aristóteles; Justiça; Virtude.ABSTRACTThis article is a justice theme this analysis in Book V of the “Nicomachean Ethics” work of the Greek philosopher Aristotle. This takes into account the various issues pertaining to the term as presents the philosopher himself. Because of this, start by allocating justice as a virtue par excellence. Later proceeds to analyze the meaning and later distinction between full justice and particular justice (the latter distinguishes distributive justice corrective justice), political justice and domestic justice, natural justice and legal justice, the designation of justice as fairness, the relationship between friendship and justice and, finally, a judge as lively justice.Keywords: Aristotle; Justice; Virtue.RESUMENEste artículo es un tema de justicia este análisis en el Libro V de la obra “Ética a Nicómaco” del filósofo griego Aristóteles. Esto toma en cuenta las diversas cuestiones relacionadas con el término como se presenta el propio filósofo. Debido a esto, comenzar mediante la asignación de la justicia como una virtud por excelencia. Posteriormente se procede a analizar el significado y más tarde completa distinción entre la justicia y la justicia particular (este último distingue la justicia distributiva justicia correctiva), la justicia política y la justicia doméstica, la justicia natural y la justicia legal, la designación de la justicia como equidad, la relación entre la amistad y la justicia y, por último, una justicia tan viva la justicia.Palabras clave: Aristóteles; Justicia; Virtud.
O BRASIL E A CRENÇA NUM FUTURO QUE NUNCA SE REALIZA: reflexões sobre as formas de reconhecimento do sujeito brasileiro
Authors: Piretti Brandão Ramon Taniguchi
Published: December 2018

BRAZIL AND THE BELIEF IN A FUTURE THAT NEVER TAKES PLACE: reflections about the forms of recognition of the Brazilian guyEL BRASIL Y LA CRENZA EN UN FUTURO QUE NUNCA SE REALIZA: reflexiones sobre las formas de reconocimiento del sujeto brasileñoO presente artigo trata das formas de reconhecimento através das quais o sujeito brasileiro se reconhece. Dentre os elementos que compõem essas formas, está a memória e o imaginário nacional. Veremos que, no Brasil, os mitos nacionais não ajudam a organizar, não têm um papel organizador da sociedade (como em outros países), mas, antes, são instrumentos de autoilusão. O drama do país, assim, jaz no contraste entre imaginário (ou sonho) e realidade. Entre aspiração (aquilo que gostaríamos de ser) e realização (aquilo que somos na prática). Ainda veremos que o aspecto social está totalmente desvinculado do aspecto político no Brasil (ao contrário do que vemos em países desenvolvidos).Palavras-chave: Brasil; Reconhecimento; História; Memória Nacional.ABSTRACTThis article deals with the forms of recognition through which the brazilian subject is recognized. Among the elements that make up these forms, they are memory and the national imagination. We see that in Brazil, the national myths do not help to organize, do not have an organizing role of society (as in other countries), but rather are self-delusion instruments. The country’s drama thus lies in the contrast between imaginary (or dream) and reality. Between aspiration (what we would like to be) and realization (what we are in practice). We will see that the social aspect is completely detached from the political aspect in Brazil (unlike what we see in developed countries).Keywords: Brazil; Recognition; History; National Memory.RESUMENEl presente artículo trata de las formas de reconocimiento a través de las cuales el sujeto brasileño se reconoce. Entre los elementos que componen esas formas, está la memoria y el imaginario nacional. Veremos que, en Brasil, los mitos nacionales no ayudan a organizar, no tienen un papel organizador de la sociedad (como en otros países), pero, antes, son instrumentos de auto ilusión. El drama del país, así, yace en el contraste entre imaginario (o sueño) y realidad. Entre aspiración (lo que nos gustaría ser) y realización (lo que somos en la práctica). Aún veremos que el aspecto social está totalmente desvinculado del aspecto político en Brasil (al contrario de lo que vemos en países desarrollados).Palabras clave: Brasil; Reconocimiento; Historia; Memoria Nacional.
FERREIRA, Gustavo H. Cepolini (Org.). Geografia Agrária no Brasil: disputas, conflitos e alternativas territoriais. Jundiaí-SP: Paco Editorial, 2016.
Authors: Mata Célia De Assis
Published: December 2018

O foco da referida coletânea é analisar os inúmeros contextos dos conflitos, disputas e alternativas territoriais existentes no campo brasileiro. Na apresentação, o organizador evidencia que: “Trata-se de uma coletânea que reflete alguns cenários importantes do campo brasileiro, cuja conflitualidade e a barbárie estão territorializadas em função do modelo predominante no país, ou seja, o agronegócio em detrimento da agricultura camponesa” (FERREIRA, 2016, p. 11).
TACTICS OF ORTHODONTICAL ADMINISTRATION PATIENTS WITH HYPERPLETE EDUCATION OF THE MAXIMUM BONE
Authors: Bolovina Ya. P , Vologyna M. V , Fomenko I. V , Zhuravskaya N. S
Published: December 2018

The incidence and localization of hyperplastic jawbone formations in men and women in the city of Volgograd was determined according to the data of X-ray studies. An algorithm for managing patients with hyperplane jawbones in an orthodontic treatment is proposed.
THE NORM AND THE LOGARITHMIC NORM OF INFINITE MATRICES
Authors: Kleshchina Olga Igorevna
Published: December 2018

In this paper the norm and the logarithmic norm of infinite matrices in the l_σ space are studied. Various estimates of these quantities are obtained.
HURWITZ MATRIX, LYAPUNOV AND DIRICHLET ON THE SUSTAINABILITY OF LYAPUNOV’S
Authors: Kostrub Irina Dmitrievna
Published: December 2018

The concepts of Hurwitz, Lyapunov and Dirichlet matrices are introduced for the convenience of the stability of linear systems with constant coefficients. They allow us to describe all the cases of interest in the stability theory of linear systems with constant coefficients. A similar classification is proposed for systems of linear differential equations with periodic coefficients. Monodromy matrices of such systems can be either Hurwitz matrices or Lyapunov matrices or Dirichlet matrices (in the discrete sense) in a stable case. The new material relates to systems with variable coefficients.
ON EXACT SOLUTION OF OPTIMIZATION TASK GENERATED BY THE LAPLACE EQUATION
Authors: Mzedawee Asaad Naser
Published: December 2018

A one-parameter family of finite-dimensional spaces consisting of special two-dimensional splines of Lagrangian type is defined (the parameter N is related to the dimension of the space). The Laplace equation generates in each such space the problem of minimizing the residual functional. The existence and uniqueness of optimal splines are proved. For their coefficients and residuals, exact formulas are obtained. It is shown that with increasing N; the minimum of the residual functional is O(N^(-5) ); and the special sequence consisting of optimal splines is fundamental.
THE STRONG-NORM CONVERGENCE OF A PROJECTION-DIFFERENCE METHOD OF SOLUTION OF A PARABOLIC EQUATION WITH THE PERIODIC CONDITION ON THE SOLUTION
Authors: Bondarev Andrei Sergeevich
Published: December 2018

A smooth soluble abstract linear parabolic equation with the periodic condition on the solution is treated in a separable Hilbert space. This problem is solved approximately by a projection-difference method using the Galerkin method in space and the implicit Euler scheme in time. Effective both in time and in space strong-norm error estimates for approximate solutions, which imply convergence of approximate solutions to the exact solution and order of convergence rate depending of the smoothness of the exact solution, are obtained.
Comparison of Length of Stay and Deep Vein Thrombosis (DVT) Incidents in Dr. Soetomo Hospital
Authors: Hanindito Elizeus , Airlangga Prananda Surya , Sulistiawan Soni Sunarso , Semedi Bambang Pujo , Andriyanto Lucky , Utariani Arie , Rehatta Nancy Margarita
Published: December 2018

Vein thrombosis may occur both in deep and superficial vein of all extremities. Ninety percent of vein thrombosis may progress into pulmonary embolism which is lethal. Deep vein thrombosis (DVT) is frequently found in critically ill patients in ICU, especially patients who are treated for a long time. This study aims to analyse the comparison between length of stay and DVT incidents in critically ill patients. A cross-sectional study was employed. We include all patients who were 18 years or older and  were treated in ICU of Dr Soetomo public hospital for at least 7 days. The patients were examined with Sonosite USG to look for any thrombosis in iliac, femoral, popliteal, and tibial veins and Well’s criteria were also taken. This study showed that length of stay is not the only risk factor for DVT in patients treated in ICU. In our data, we found out that the length of treatment did not significantly cause DVT. Other risk factors such as age and comorbidities in patients who are risk factors may support the incidence of DVT events. The diagnosis of DVT is enforced using an ultrasound performed by an expert in the use of ultrasound to locate thrombus in a vein. Length of treatment is not a significant risk factor for DVT. Several other factors still need to be investigated in order for DVT events to be detected early and prevented.
Increased Activity Of Mature Osteoblast from Rat Bone Marrow-Mesenchymal Stem Cells tn Osteogenic Medium Exposed to Melatonin
Authors: Purnama Yugi Hari Chandra , Mastutik Gondo , Putra Suhartono Taat
Published: December 2018

Exposure to melatonin in the cultures of Bone Marrow Mesenchymal Stem Cells (BM-MSCs) in osteogenic medium is able to induce mesenchymal stem cells and preosteoblasts into active osteoblasts via several transduction signals such as ERK 1/2. Previous studies used a single dose of 50 nM and a physiological dose of 20-200 pg/ml. The objective of the study was to obtain an optimal dose of melatonin that enhances osteoblast activity by increasing the expression of ERK1/2 and ALP levels in the culture of Rat Bone Marrow Mesenchymal Stem Cells (BM-MSCs) in osteogenic medium. This study was an in vitro experimental laboratory study using BM-MSCs from rat femoral bone grown on osteogenic medium without or with exposure to melatonin in doses of 0, 50, 100, 150 nM for 21 days. BM-MSCs were characterized by immunocytochemical techniques (CD45- and CD 105+) and ERK 1/2 expression was checked 24 hours after exposure to melatonin, while ALP levels were examined on day 21 using ELISA technique. ERK 1/2 expression on BM-MScs exposed to melatonin in doses 0, 50, 100, and 150 nM were respectively 0.087, 0.095, 0.081, and 0.079. Mean ERK 1/2 expression in various groups showed a decrease along with increasing doses of melatonin. Among the four treatment groups, the administration of melatonin in a dose of 50 nM resulted in highest mean ERK 1/2 expression. ALP levels in BM-MSCs exposed to melatonin doses of 0, 50, 100, and 150 nM were 0.128; 0.130; 0.117, and 0.111 ng/ml respectively. Data showed that decreasing mean ALP levels occurred along with the addition of melatonin dose. In conclusion, the administration of melatonin 50 nM is the optimal dose to increase the differentiation of cultured rat BM-MSCs into active osteoblasts.
Review article: Neonatal Sepsis in Thailand
Authors: Thatrimontrichai Anucha
Published: December 2018

Neonatal sepsis is a burden around the world and causes high mortality and morbidity as well. Long-term neurodevelopmental disability may occur in survivors. General physicians, pediatricians, and neonatologists need be attentive to the proper diagnosis, starting, de-escalating or stopping empirical antimicrobials therapy in neonatal sepsis. Furthermore, multidrug resistant organisms have emerged among adults, children, and neonates in developing countries. Local epidemiology studies and antimicrobial stewardship programs are important for application of the best and specific treatments. Knowledge, definitions, and clinical practice of neonatal sepsis are updated in this review.
FAKTOR PERILAKU PENGGUNAAN ALAT PELINDUNG DIRI (APD) PADA PEKERJA PT. X
Authors: Dahyar Chyntiya Permata
Published: December 2018

Indonesia merupakan Negara berkembang yang memiliki banyak kekayaan alam sehingga kekayaan alam tersebut dapat dimanfaatkan dalam mengembangkan sektor-sektor yang ada di Indonesia salah satunya adalah sektor industri. Perkembangan sektor industri membuat adanya peralihan alat-alat yang bersifat manual menjadi mesin/peralatan yang lebih canggih yang dapat menimbulkan hal negatif seperti kecelakaan kerja. Kecelakaan kerja dapat terjadi disebabkan oleh unsafe conditions dan unsafe acts. Peningkatan sektor industri berbanding dengan peningkatan tenaga kerja sehingga harus berbanding lurus dengan perlindungan yang diberikan kepada tenaga kerja berupa Kesehatan dan Keselamatan Kerja pekerja. Perlindungan tersebut dapat dengan pengendalian kecelakaan kerja yang mana pengendalian kecelakaan kerja diperlukan untuk mengurangi dan mencegah terjadinya kecelakaan kerja yaitu dengan 5 hierarkhi pengendalian kecelakaan kerja yaitu eliminasi, substitusi, perancangan, administratif, dan alat pelindung diri. Perusahaan relatif menggunakan alat pelindung diri sebagai upaya terakhir dalam pengendalian kecelakaan kerja jika pengendalian lain sudah dilakukan namun masih terdapat potensi-potensi bahaya. Kecelakaan kerja juga disebabkan oleh unsafe behavior sehingga diperlukan perilaku pekerja dalam menggunakan alat pelindung diri. PT. X merupakan perusahaan Badan Usaha Milik Negara (BUMN) yang bergerak di bidang industri galangan kapal, yang kegiatan utamanya adalah memproduksi kapal dan perbaikan serta pemeliharaan kapal. PT.X memiliki program berbasis safety behavior seperti safety talk, induction, meeting, patrol, hingga sidak yang mengkaji terkait isu-isu kesehatan dan keselamatan kerja. Penelitian ini bertujuan untuk mengetahui faktor-faktor apa saja yang berhubungan dengan perilaku penggunaan alat pelindung diri (APD). Metode dalam penelitian ini adalah observasional analitik dengan pendekatan kuantitatif dan menggunakan desain cross sectional. Hasil penelitian ini menunjukan bahwa faktor yang mempengaruhi perilaku penggunaan alat pelindung diri adalah sikap. Sikap terbentuk dari persepsi manfaat, dan persepi kemudahan yang saling berhubungan signifikan terhadap sikap.  Kata Kunci: perilaku, persepsi, manfaat, kemudahan, alat pelindung diri (APD), kecelakaan kerja.
Relationship between Air Diffusivity and Permeability Coefficients of Cementitious Materials
Authors: Sakai Yuya
Published: December 2018

In this study, the relationship between air diffusivity and permeability in cementitious materials was investigated. First, we derived an equation to correlate air diffusivity and permeability in a straight circular tube. Then, we reviewed existing studies that measured both air diffusivity and permeability and compared reported data and calculated values to verify the applicability of the derived equation to cementitious materials. Although a correction factor was not used, the two sets of data showed good agreement quantitatively. This indicates that the derived equation can be applied to cementitious materials including concrete, and measured air diffusivity can be converted to permeability of concrete and vice versa using the derived equation.
Levinas, Simmel, and the Ethical Significance of Money
Authors: Buckman Christopher
Published: December 2018

An examination of Emmanuel Levinas’ writings on money reveals his distance from—and indebtedness to—a philosophical predecessor, Georg Simmel. Levinas and Simmel share a phenomenological approach to analyses of the proximity of the stranger, the importance of the face, and the interruption of the dyadic relationship by the third. Money is closely linked to the conception of totality because money is the medium that compares heterogeneous values. Levinas goes beyond Simmel in positing an ethical relation to money permitting transcendence.
Why Nature-Based Solutions to Climate Change Must Be Grounded in Sound Biodiversity Science
Authors: Seddon Nathalie , Turner Beth , Berry Pam , Chausson Alexandre , Girardin Cécile A.J.
Published: December 2018

The current focus on afforestation in climate policy runs the risk of compromising both longterm carbon storage and human adaptation. It also works against efforts to stem the tide of biodiversity loss. We outline why an emphasis on diverse, intact natural ecosystems—as opposed to tree plantations with fast-growing exotic species—will help nations deliver the goals of the Paris Agreement and much more.
The User-Pleasant Video Skimming by Multi-Modal Keywords Semantics
Authors: Shen Yiqing
Published: December 2018

In this paper, we propose a novel approach of video skimming by exploiting the fusion of video temporal information and keyword information representation extracted from multi-model video information including audio, text and visual indices. In addition, we introduce the brand-safe filtering and sentiment analysis in order to only reserve the user-friendly content in the video skim. In the experiment by using the videos from YouTube-8M dataset, we have proved that the semantic conservation in the video skim from the proposed approach highly outperforms the approaches by only partial  information of the video in conserving the semantic content of the video.
PHOSPHAN Microplate Technology-Based Microarray For Detection of IgG Antibodies against West Nile, Crimean Congo Hemorrhagic Fever and Tick-Borne Encephalitis Viruses
Authors: Pomelova V. G. , Bychenkova T. A. , Ossin N. S.
Published: December 2018

Demonstrated was the possibility to use PHOSPHAN microplate technology to examine human sera and detect simultaneously specific IgG antibodies to three arboviruses, including the West Nile virus (WNV), Crimean Congo Hemorrhagic Fever virus (CCHFV), and Tick-borne encephalitis virus (TBEV). Both sensitivity and specificity of microarray immunoassay approach were similar to those of ELISA tests (when serum specimens were investigated separately). Using the criterion of 2-fold or stronger reaction of the examined serum specimen with homologous antigen than with heterologous one, we succeeded in differentiation of group specific anti WNV and anti TBEV IgG antibodies in about 60% of cross reactive sera. From the economical standpoint, the PHOSPAN technology may have advantages as compared with currently used ELISAs due to miniaturization of immunoassay format and ability to multiplex.
Diagnostic Mistakes as Regards Chronic Form of Brucellosis
Authors: Sergeeva I. V.
Published: December 2018

Analyzed were case records of patients with chronic brucellosis for the period of 1994-2009. Presented are the examples from the disease anamnesis of the patients examined in the infectious unit of Krasnoyarsk municipal hospital, with diagnosis of brucellosis established not in time. The reasons of diagnostic mistakes in various forms of brucellosis are considered.
Introduction of the Pelleted Smallpox Vaccine TEOVak into Serial Production to Provide Biosafety of the Population of the Russian Federation
Authors: Bondarev V. P. , Terent`ev A. I. , Melnicov S. A. , Bondareva T. A.
Published: December 2018

The industrial basis was developed and licensed to produce effective pelleted oral smallpox vaccine TEOVak in the Virologic Centre. Several series of TEOVak preparation were produced in accordance with the industrial technology on a built-in processing line consisting of blocks and modules. Certification and evaluation of preparation's quality indices in the process of storage were carried out. Results of the evaluation proved the conformity of vaccine's characteristics with the requirements of the normative technologic documentation.
Current State of Problem of Mathematical Modeling and Prognosis of the Epidemic Process
Authors: Lopatin A. A. , Safronov V. A. , Razdorskiy A. S. , Kouklev E. V.
Published: December 2018

Short systematic review on the modeling methods in medicine and epidemiology is presented. In particular, special native and foreign examples of application of mathematical modeling and prognosis of epidemic process are described.
Geographical Information System for Epidemiological Surveillance of Natural Focal Infectious Diseases in Combined Foci in the Territory of the Astrakhan Region
Authors: Safronov V. A. , Razdorskiy A. S. , Skalenko S. Yu. , Lopatin A. A. , Kovtunov A. I. , Piskunova N. V. , Kologorov A. I. , Kouklev E. V. , Toporkov V. P.
Published: December 2018

Spatial analysis of long-term combined epidemic manifestations of some natural focal infectious diseases in the territory of the Astrakhan region was carried out using geographical information system. Suggested is the method to detect territories where these combined epidemic manifestations are stable and its high effectiveness and predictive value are demonstrated. On the basis of received data suggested are the measures to increase the effectiveness of epidemiologic surveillance for natural focal infectious diseases.
Improvement of Oligonucleotide Primers Synthesis Technology for PCR Test Systems Production
Authors: Stepanov A. V. , Mayorov N. V. , Nikiforov A. K.
Published: December 2018

The investigations carried out resulted in the improvement of technology of synthesis of the oligonucleotide primers, components of the PCR test systems produced in the RARI Microbe. The final product output was demonstrated to increase by 93 % when 25 % aquatic ammonium solution was used for ammonolysis, and by 16 % if solutions Cap A N1 and Cap B N 3 were used at the stage of capping. Application of the improved technology of oligonucleotide synthesis for gene diagnostic preparations production will permit to increase the amount of the output products and reduce expenses for high-priced reagents.
Características del adulto mayor institucionalizado en el área metropolitana de Monterrey
Authors: Coindreau-Frias Fernando , Ramos-Bacco Mauricio , Barba-Marines Alejandra , Gutiérrez-Torres Aníbal , Barrera-Saldaña Hugo Alberto , Valero-Gómez Javier
Published: December 2018

[No disponible]
Prevention of cervical cancer in Latin America: Future challenges and opportunities
Authors: Franco Eduardo L.
Published: December 2018

[Not available]
Prevention of Stem-base Splitting in Cut Hippeastrum Flowers
Authors: Halevy Abraham H. , Kofranek Anton M.
Published: December 2018

Splitting and out-rolling of the stem bases in cut flowers of Hippeastrum Xhybridum was prevented by a 1-day-pulse treatment with 0.125 m sucrose. Pulsing also slightly increased vase life and promoted the opening of all the flower buds on the stem.
Green Industry Survey of Native Plant Marketing in the Southeastern United States
Authors: Brzuszek Robert F. , Harkess Richard L.
Published: December 2018

Recent studies have shown that the use of native plants by landscape architects and contractors in the southeastern United States has increased as has the clientele interest level in native plants. Recommendations to increase the use of native species by the landscape industry in this region include increasing the number of nurseries carrying native plants and the quantities and species currently available. To understand how green industry professionals view the opportunities and constraints of the current southeastern United States native plant market and to synthesize the connections between landscape architect's demands and the supplies of the nursery industry in this region, a questionnaire was developed and e-mailed to southeastern U.S. wholesale and retail nurseries in six states. The survey included questions regarding nursery stock, demand, and species sold. A total of 129 responses were received, and they revealed that while there is a perceived increase in customer interest in native plants, market demand and enhanced public education play a key role in further development of this growing market.
Weed Control in Christmas Trees with Flumioxazin and Other Residual Herbicides Applied Alone or in Tank Mixtures
Authors: Richardson Robert J. , Zandstra Bernard H.
Published: December 2018

Four studies were conducted from 2001 to 2004 in Michigan to determine Christmas tree tolerance and weed control with flumioxazin and other herbicide treatments. In Study 1, fraser fir (Abies fraseri) leader length was greater with fall-applied flumioxazin (0.38 lb/acre) than with halosulfuron (0.21 lb/acre), isoxaben (1 lb/acre), oxyfluorfen (1 lb/acre), simazine (2 lb/acre), or sulfentrazone (0.5 lb/acre). Flumioxazin applied in the fall provided preemergent control of common ragweed (Ambrosia artemisiifolia), field violet (Viola arvensis), and hoary alyssum (Berteroa incana) 79% to 98% the following summer. Preemergence weed control with the other herbicides was more variable. In Study 2, fraser fir treated in the spring with oxyfluorfen had the shortest leader length (terminal stem growth of the current growing season) at 4.3 inches. Trees treated in the spring with flumioxazin, isoxaben, simazine, and sulfentrazone had leader lengths of 6.7 to 8.7 inches. Flumioxazin applied preemergence in the spring controlled common ragweed 80%, but controlled field violet, hoary alyssum, and white campion (Silene alba) only 43% to 64%. In Study 3, fall-applied flumioxazin alone did not injure colorado blue spruce (Picea pungens). However, mixtures of flumioxazin plus pendimethalin (3 lb/acre) caused 5% and 6% tree injury at 6 months after treatment (MAT) and sulfentrazone plus pendimethalin caused 9% and 23% injury at 6 MAT in 2003 and 2004, and 52% injury at 9 MAT in 2004. There was no significant injury to the trees treated with isoxaben plus pendimethalin, oxyfluorfen plus pendimethalin, or simazine plus pendimethalin in 2003 and 2004. Leader length was reduced by sulfentrazone plus pendimethalin compared with flumioxazin plus pendimethalin and oxyfluorfen plus pendimethalin. Flumioxazin plus pendimethalin provided 84% to 88% preemergence control of annual grasses, common catsear (Hypochoeris radicata), horseweed (Conyza canadensis), and virginia pepperweed (Lepidium virginicum). In Study 4, spring-applied mixtures of flumioxazin plus pendimethalin resulted in minor (2%–10%) visual injury to colorado blue spruce, although leader length at the end of the season did not differ significantly from the control. In summary, flumioxazin controlled several weed species with acceptable selectivity in colorado blue spruce and fraser fir Christmas trees.