bluuebunny/crossref_metadata_2025 huggingface dataset:
Supplementary Figure 3 from Stearoyl-CoA Desaturase 1 Is a Novel Molecular Therapeutic Target for Clear Cell Renal Cell Carcinoma
Authors: von Roemeling Christina A. , Marlow Laura A. , Wei Johnny J. , Cooper Simon J. , Caulfield Thomas R. , Wu Kevin , Tan Winston W. , Tun Han W. , Copland John A.
Published: April 2023

Supplementary Figure 3:SCD1 inhibition induces ATF6 - PDF file 844K, ATF6 is activated in response to SCD1 inhibition in ccRCC
Supplementary Figure 3 from T Lymphocytes Redirected against the Chondroitin Sulfate Proteoglycan-4 Control the Growth of Multiple Solid Tumors both In Vitro and In Vivo
Authors: Geldres Claudia , Savoldo Barbara , Hoyos Valentina , Caruana Ignazio , Zhang Ming , Yvon Eric , Del Vecchio Michele , Creighton Chad J. , Ittmann Michael , Ferrone Soldano , Dotti Gianpietro
Published: April 2023

PDF file - 179K, CSPG4 mRNA expression levels in normal tissues. Top panel, CSPG4 expression across normal human tissues represented in the Novartis GeneAtlas dataset (http://biogps.org). Values represented are relative and the average of Affymetrix probe sets 214297_at and 204736_s_at. Highlighted are normal tissues for which corresponding normal adjacent tissue data were available in TCGA datasets. Bottom panel, CSPG4 mRNA expression by TCGA in a variety of solid tumors (featured in main Figure 1D) and normal adjacent tissues (the normal tissues being also represented in GeneAtlas), with the cancers showing higher CSPG4 levels over that of the normal samples. Note shown is log2 scale.
Supplementary Table 3 from MGMT-STP27 Methylation Status as Predictive Marker for Response to PCV in Anaplastic Oligodendrogliomas and Oligoastrocytomas. A Report from EORTC Study 26951
Authors: van den Bent Martin J. , Erdem-Eraslan Lale , Idbaih Ahmed , de Rooi Johan , Eilers Paul H.C. , Spliet Wim G.M. , den Dunnen Wilfred F.A. , Tijssen Cees , Wesseling Pieter , Sillevis Smitt Peter A.E. , Kros Johan M. , Gorlia Thierry , French Pim J.
Published: April 2023

Supplementary Table 3 - PDF file 61K, Molecular markers associated with methylation status
Supplementary Table 1 from Molecular Classification of Malignant Pleural Mesothelioma: Identification of a Poor Prognosis Subgroup Linked to the Epithelial-to-Mesenchymal Transition
Authors: de Reyniès Aurélien , Jaurand Marie-Claude , Renier Annie , Couchy Gabrielle , Hysi Ilir , Elarouci Nabila , Galateau-Sallé Françoise , Copin Marie-Christine , Hofman Paul , Cazes Aurélie , Andujar Pascal , Imbeaud Sandrine , Petel Fabien , Pairon Jean-Claude , Le Pimpec-Barthes Francoise , Zucman-Rossi Jessica , Jean Didier
Published: April 2023

XLS file - 212KB, Sample annotations and gene expression.
Supplementary Figure 4 from Margin-Infiltrating CD20+ B Cells Display an Atypical Memory Phenotype and Correlate with Favorable Prognosis in Hepatocellular Carcinoma
Authors: Shi Jie-Yi , Gao Qiang , Wang Zhi-Chao , Zhou Jian , Wang Xiao-Ying , Min Zhi-Hui , Shi Ying-Hong , Shi Guo-Ming , Ding Zhen-Bin , Ke Ai-Wu , Dai Zhi , Qiu Shuang-Jian , Song Kang , Fan Jia
Published: April 2023

PDF file - 498K, Representative flow cytometry data showing that percentages of granzyme B+ and TRAIL+ cells in total CD20+ cells are significantly higher in MIL-Bs than in PIL-Bs, respectively (n=5).
Supplementary Methods from JMJD2B Promotes Epithelial–Mesenchymal Transition by Cooperating with β-Catenin and Enhances Gastric Cancer Metastasis
Authors: Zhao Li , Li Wenjuan , Zang Wen , Liu Zhifang , Xu Xia , Yu Han , Yang Qing , Jia Jihui
Published: April 2023

PDF file - 202K
Supplementary Table 2 from BRAF Inhibition Is Associated with Enhanced Melanoma Antigen Expression and a More Favorable Tumor Microenvironment in Patients with Metastatic Melanoma
Authors: Frederick Dennie T. , Piris Adriano , Cogdill Alexandria P. , Cooper Zachary A. , Lezcano Cecilia , Ferrone Cristina R. , Mitra Devarati , Boni Andrea , Newton Lindsay P. , Liu Chengwen , Peng Weiyi , Sullivan Ryan J. , Lawrence Donald P. , Hodi F. Stephen , Overwijk Willem W. , Lizée Gregory , Murphy George F. , Hwu Patrick , Flaherty Keith T. , Fisher David E. , Wargo Jennifer A.
Published: April 2023

PDF file - 30K, Inhibition of BRAFV600E increases expression of MDAs in tumors of patients with metastatic melanoma.
Supplementary Table 1, Figure 1 from Competing Risks and Multistate Models
Authors: Schmoor Claudia , Schumacher Martin , Finke Jürgen , Beyersmann Jan
Published: April 2023

PDF file - 86K, Supplementary Table illustrating the mechanism of an analysis based on subdistribution hazards using a simple data example. Supplementary Figure showing the Kaplan-Meier estimate of the incidence of the composite endpoint aGvHD III-IV or death (figure A) and Aalen-Johansen estimates of the incidences of the competing events aGvHD III-IV (figure B) and death without prior aGvHD III-IV (figure C).
Supplementary Figure 1 from Phase I Study of BIIB028, a Selective Heat Shock Protein 90 Inhibitor, in Patients with Refractory Metastatic or Locally Advanced Solid Tumors
Authors: Hong David , Said Rabih , Falchook Gerald , Naing Aung , Moulder Stacy , Tsimberidou Apostolia-Maria , Galluppi Gerald , Dakappagari Naveen , Storgard Chris , Kurzrock Razelle , Rosen Lee S.
Published: April 2023

Supplementary Figure 1 - PDF file 51K, Kinetics of HSP70 Induction in human PBMC treated ex vivo with 2uM BIIB028
Supplementary Methods, Table 1 from Inactivation or Loss of TTP Promotes Invasion in Head and Neck Cancer via Transcript Stabilization and Secretion of MMP9, MMP2, and IL-6
Authors: Van Tubergen Elizabeth A. , Banerjee Rajat , Liu Min , Broek Robert Vander , Light Emily , Kuo Shiuhyang , Feinberg Stephen E. , Willis Amanda L. , Wolf Gregory , Carey Thomas , Bradford Carol , Prince Mark , Worden Francis P. , Kirkwood Keith L. , D'Silva Nisha J.
Published: April 2023

PDF file, 108K, Q-RT-PCR primers used for verification of transcript
Supplementary Table 2 from A Genome-Wide Aberrant RNA Splicing in Patients with Acute Myeloid Leukemia Identifies Novel Potential Disease Markers and Therapeutic Targets
Authors: Adamia Sophia , Haibe-Kains Benjamin , Pilarski Patrick M. , Bar-Natan Michal , Pevzner Samuel , Avet-Loiseau Herve , Lode Laurence , Verselis Sigitas , Fox Edward A. , Burke John , Galinsky Ilene , Dagogo-Jack Ibiayi , Wadleigh Martha , Steensma David P. , Motyckova Gabriela , Deangelo Daniel J. , Quackenbush John , Stone Richard , Griffin James D.
Published: April 2023

PDF file - 68K, Table summarize results of annotation analyses of aberrantly spliced transcripts detected in AML patients as compared to normal donors.
Supplementary Figure 4 from Preclinical and Early Clinical Evaluation of the Oral AKT Inhibitor, MK-2206, for the Treatment of Acute Myelogenous Leukemia
Authors: Konopleva Marina Y. , Walter Roland B. , Faderl Stefan H. , Jabbour Elias J. , Zeng Zhihong , Borthakur Gautam , Huang Xuelin , Kadia Tapan M. , Ruvolo Peter P. , Feliu Jennie B. , Lu Hongbo , Debose LaKiesha , Burger Jan A. , Andreeff Michael , Liu Wenbin , Baggerly Keith A. , Kornblau Steven M. , Doyle L. Austin , Estey Elihu H. , Kantarjian Hagop M.
Published: April 2023

PDF file - 145KB, The subtraction heat maps of selected markers in paired PB samples.
Supplementary Figure 2 from Inactivation or Loss of TTP Promotes Invasion in Head and Neck Cancer via Transcript Stabilization and Secretion of MMP9, MMP2, and IL-6
Authors: Van Tubergen Elizabeth A. , Banerjee Rajat , Liu Min , Broek Robert Vander , Light Emily , Kuo Shiuhyang , Feinberg Stephen E. , Willis Amanda L. , Wolf Gregory , Carey Thomas , Bradford Carol , Prince Mark , Worden Francis P. , Kirkwood Keith L. , D'Silva Nisha J.
Published: April 2023

PDF file - 392K, Supplementary Figure S2 Whole cell lysates from UM-SCC-1 cells transfected with NT and different siRNAs against TTP, were immunoblotted with TTP and actin antibodies. Signal intensity was quantified, normalized to the actin loading control and expressed as percent of NT.
Supplementary Figure 3 from Preclinical and Early Clinical Evaluation of the Oral AKT Inhibitor, MK-2206, for the Treatment of Acute Myelogenous Leukemia
Authors: Konopleva Marina Y. , Walter Roland B. , Faderl Stefan H. , Jabbour Elias J. , Zeng Zhihong , Borthakur Gautam , Huang Xuelin , Kadia Tapan M. , Ruvolo Peter P. , Feliu Jennie B. , Lu Hongbo , Debose LaKiesha , Burger Jan A. , Andreeff Michael , Liu Wenbin , Baggerly Keith A. , Kornblau Steven M. , Doyle L. Austin , Estey Elihu H. , Kantarjian Hagop M.
Published: April 2023

PDF file - 50KB, Correlation between RPPA and immunoblotting in samples from the patients treated on MK-2206 trial.
Supplementary Tables 1 - 7 from Oncogenic Function of SCCRO5/DCUN1D5 Requires Its Neddylation E3 Activity and Nuclear Localization
Authors: Bommeljé Claire C. , Weeda Víola B. , Huang Guochang , Shah Kushyup , Bains Sarina , Buss Elizabeth , Shaha Manish , Gönen Mithat , Ghossein Ronald , Ramanathan Suresh Y. , Singh Bhuvanesh
Published: April 2023

PDF file - 113K, Supplementary Table S1. Oral squamous cell carcinoma- patient and tumor characteristics. Supplementary Table S2. Lung squamous cell carcinoma -patient and tumor characteristics. Supplementary Table S3. Thyroid Carcinoma -patient and tumor characteristics. Supplementary Table S4. Lung neuroendocrine carcinoma -patient and tumor characteristics. Supplementary Table S5. Sequences of the real-time PCR primers for SCCRO5 and housekeeping gene GAPDH (in 5'-3' direction) Supplementary Table S6. Sequences of the DNA mutation analysis primers for SCCRO5 Supplementary Table S7. Sequences of the primers used for SCCRO5 PCR for deletion and mutagenesis.
Figure S4 from Consistent and Differential Genetic Aberrations between Esophageal Dysplasia and Squamous Cell Carcinoma Detected By Array Comparative Genomic Hybridization
Authors: Shi Zhi-Zhou , Shang Li , Jiang Yan-Yi , Hao Jia-Jie , Zhang Yu , Zhang Tong-Tong , Lin De-Chen , Liu Shu-Guang , Wang Bo-Shi , Gong Ting , Zhan Qi-Min , Wang Ming-Rong
Published: April 2023

Genomic aberrations in esophgeal dysplasia and ESCC. A. Validation of 11q13.3 amplification by FISH. Left: 11q13.3 amplification detected by array CGH. Right: FISH results. B. Comparison of the number of aberrations between dysplasia and ESCC.
Figure S3 from Consistent and Differential Genetic Aberrations between Esophageal Dysplasia and Squamous Cell Carcinoma Detected By Array Comparative Genomic Hybridization
Authors: Shi Zhi-Zhou , Shang Li , Jiang Yan-Yi , Hao Jia-Jie , Zhang Yu , Zhang Tong-Tong , Lin De-Chen , Liu Shu-Guang , Wang Bo-Shi , Gong Ting , Zhan Qi-Min , Wang Ming-Rong
Published: April 2023

Venn diagrams comparing differences in expression of our gene/microRNA expression assay and other microarray experiments. A. Comparison of differentially expressed genes in different experiments. B. Comparison of differentially expressed microRNAs in different experiments. â†', overexpressed; â†", underexpressed.
Figure S1 from Consistent and Differential Genetic Aberrations between Esophageal Dysplasia and Squamous Cell Carcinoma Detected By Array Comparative Genomic Hybridization
Authors: Shi Zhi-Zhou , Shang Li , Jiang Yan-Yi , Hao Jia-Jie , Zhang Yu , Zhang Tong-Tong , Lin De-Chen , Liu Shu-Guang , Wang Bo-Shi , Gong Ting , Zhan Qi-Min , Wang Ming-Rong
Published: April 2023

Frequency plot comparison analysis. A. Frequency plot comparison of ESCC with or without lymph node metastasis. B. Frequency plot comparison of ESCC at different stages.
Supplementary Figure 1 from Epstein-Barr Virus DNA Load in Nasopharyngeal Brushings and Whole Blood in Nasopharyngeal Carcinoma Patients before and after Treatment
Authors: Adham Marlinda , Greijer Astrid E. , Verkuijlen Sandra A.W.M. , Juwana Hedy , Fleig Sabine , Rachmadi Lisnawati , Malik Octavia , Kurniawan A.N. , Roezin Averdi , Gondhowiardjo Soehartati , Atmakusumah Djumhana , Stevens Servi J.C. , Hermani Bambang , Tan I. Bing , Middeldorp Jaap M.
Published: April 2023

PDF file - 44K, Comparison of the 99bp and 213bp PCR for measuring the EBV DNA load in NP brushings. Both primer pairs gave similar results.
Supplementary Table 1 from The Combination of Sorafenib and Everolimus Abrogates mTORC1 and mTORC2 Upregulation in Osteosarcoma Preclinical Models
Authors: Pignochino Ymera , Dell'Aglio Carmine , Basiricò Marco , Capozzi Federica , Soster Marco , Marchiò Serena , Bruno Stefania , Gammaitoni Loretta , Sangiolo Dario , Torchiaro Erica , D'Ambrosio Lorenzo , Fagioli Franca , Ferrari Stefano , Alberghini Marco , Picci Piero , Aglietta Massimo , Grignani Giovanni
Published: April 2023

PDF file - 72K, Supplementary table 1. Percentage of wound healing closure calculated 16 hours after scratching osteosarcoma cell monolayers. * = p<0.05 vs. control.
Supplemental Data 1 from Adoptive Transfer of Autologous T Cells Improves T-cell Repertoire Diversity and Long-term B-cell Function in Pediatric Patients with Neuroblastoma
Authors: Grupp Stephan A. , Prak Eline Luning , Boyer Jean , McDonald Kenyetta R. , Shusterman Suzanne , Thompson Edward , Callahan Colleen , Jawad Abbas F. , Levine Bruce L. , June Carl H. , Sullivan Kathleen E.
Published: April 2023

Detailed flow cytometric analysis of expanded cells from children and adults
Supplementary Figure Legend from Combined Immunostimulatory Monoclonal Antibodies Extend Survival in an Aggressive Transgenic Hepatocellular Carcinoma Mouse Model
Authors: Morales-Kastresana Aizea , Sanmamed Miguel F. , Rodriguez Inmaculada , Palazon Asis , Martinez-Forero Ivan , Labiano Sara , Hervas-Stubbs Sandra , Sangro Bruno , Ochoa Carmen , Rouzaut Ana , Azpilikueta Arantza , Bolaños Elixabet , Jure-Kunkel Maria , Gütgemann Ines , Melero Ignacio
Published: April 2023

PDF file - 109K
Supplementary Figure 6 from Impairment of Glioma Stem Cell Survival and Growth by a Novel Inhibitor for Survivin–Ran Protein Complex
Authors: Guvenc Hacer , Pavlyukov Marat S. , Joshi Kaushal , Kurt Habibe , Banasavadi-Siddegowda Yeshavanth K. , Mao Ping , Hong Christopher , Yamada Ryosuke , Kwon Chang-Hyuk , Bhasin Deepak , Chettiar Somsundaram , Kitange Gaspar , Park In-Hee , Sarkaria Jann N. , Li Chenglong , Shakhparonov Mihail I. , Nakano Ichiro
Published: April 2023

PDF file - 1207K, Effects of LLP-3 on neurosphere formation derived from p53-intact and p53-deleted mouse neural progenitors (related to Figure 4)
Supplementary Table 3 from Tumor Genetic Analyses of Patients with Metastatic Renal Cell Carcinoma and Extended Benefit from mTOR Inhibitor Therapy
Authors: Voss Martin H. , Hakimi A. Ari , Pham Can G. , Brannon A. Rose , Chen Ying-Bei , Cunha Luis F. , Akin Oguz , Liu Han , Takeda Shugaku , Scott Sasinya N. , Socci Nicholas D. , Viale Agnes , Schultz Nikolaus , Sander Chris , Reuter Victor E. , Russo Paul , Cheng Emily H. , Motzer Robert J. , Berger Michael F. , Hsieh James J.
Published: April 2023

XLSX file - 13K, Supplementary Table S3. Impact assay run statistics on all samples.
Supplementary Table 1 from Deciphering the Mechanisms of Tumorigenesis in Human Pancreatic Ductal Epithelial Cells
Authors: Chang Zhe , Li Zhongkui , Wang Xiaoyang , Kang Ya'an , Yuan Yuhui , Niu Jiangong , Wang Huamin , Chatterjee Deyali , Fleming Jason B. , Li Min , Abbruzzese James L. , Chiao Paul J.
Published: April 2023

PDF file - 77K, Supplementary Table 1. Summary of cell proliferation, migration, and invasion; anchorageindependent growth; and tumor incidence in NOD/SCID mice in various HPDE cell lines.
Supplementary Fig. S1 from Preclinical Antitumor Activity of Cabazitaxel, a Semisynthetic Taxane Active in Taxane-Resistant Tumors
Authors: Vrignaud Patricia , Sémiond Dorothée , Lejeune Pascale , Bouchard Hervé , Calvet Loreley , Combeau Cecile , Riou Jean-François , Commerçon Alain , Lavelle François , Bissery Marie-Christine
Published: April 2023

Supplementary Fig. S1 - PDF file 60K, Taxane chemical structures
Supplementary Figure 1 from Notch Pathway Activity Identifies Cells with Cancer Stem Cell–like Properties and Correlates with Worse Survival in Lung Adenocarcinoma
Authors: Hassan Khaled A. , Wang Luo , Korkaya Hasan , Chen Guoan , Maillard Ivan , Beer David G. , Kalemkerian Gregory P. , Wicha Max S.
Published: April 2023

PDF file - 196K, Stable transduction of NCI-H1299 with Notch reporter, where GFP-bright cells regenerate GFP-dim cells, while GFP-dim cells are unable to generate GFP-bright cells.
Supplementary Table 2 from A Phase I Trial of Dasatinib, an Src-Family Kinase Inhibitor, in Combination with Paclitaxel and Carboplatin in Patients with Advanced or Recurrent Ovarian Cancer
Authors: Secord Angeles Alvarez , Teoh Deanna K. , Barry William T. , Yu Miao , Broadwater Gloria , Havrilesky Laura J. , Lee Paula S. , Berchuck Andrew , Lancaster Johnathan , Wenham Robert M.
Published: April 2023

PDF file, 50K, Response in each dosing cohort.
Supplementary Table 2 from Phosphoinositide 3-Kinase (PI3K) Pathway Alterations Are Associated with Histologic Subtypes and Are Predictive of Sensitivity to PI3K Inhibitors in Lung Cancer Preclinical Models
Authors: Spoerke Jill M. , O'Brien Carol , Huw Ling , Koeppen Hartmut , Fridlyand Jane , Brachmann Rainer K. , Haverty Peter M. , Pandita Ajay , Mohan Sankar , Sampath Deepak , Friedman Lori S. , Ross Leanne , Hampton Garret M. , Amler Lukas C. , Shames David S. , Lackner Mark R.
Published: April 2023

XLSX file - 17K, PI3K pathway alterations in NSCLC cell lines
Supplementary Figure Legends from Small-Molecule RA-9 Inhibits Proteasome-Associated DUBs and Ovarian Cancer In Vitro and In Vivo via Exacerbating Unfolded Protein Responses
Authors: Coughlin Kathleen , Anchoori Ravi , Iizuka Yoshie , Meints Joyce , MacNeill Lauren , Vogel Rachel Isaksson , Orlowski Robert Z. , Lee Michael K. , Roden Richard B.S. , Bazzaro Martina
Published: April 2023

PDF file - 112KB
Supplementary Figure Legend from Copy Number Aberrations of Genes Regulating Normal Thymus Development in Thymic Epithelial Tumors
Authors: Petrini Iacopo , Wang Yisong , Zucali Paolo A. , Lee Hye Seung , Pham Trung , Voeller Donna , Meltzer Paul S. , Giaccone Giuseppe
Published: April 2023

PDF file - 40K
Supplementary Figure 2 from Copy Number Aberrations of Genes Regulating Normal Thymus Development in Thymic Epithelial Tumors
Authors: Petrini Iacopo , Wang Yisong , Zucali Paolo A. , Lee Hye Seung , Pham Trung , Voeller Donna , Meltzer Paul S. , Giaccone Giuseppe
Published: April 2023

PDF file - 3599K, Copy number aberrations of genes regulating normal thymus development overall in the 2 cohorts.
Supplementary Figure 3 from Targeting miR-21 Inhibits In Vitro and In Vivo Multiple Myeloma Cell Growth
Authors: Leone Emanuela , Morelli Eugenio , Di Martino Maria T. , Amodio Nicola , Foresta Umberto , Gullà Annamaria , Rossi Marco , Neri Antonino , Giordano Antonio , Munshi Nikhil C. , Anderson Kenneth C. , Tagliaferri Pierosandro , Tassone Pierfrancesco
Published: April 2023

PDF file - 544K, Figure S3. Endogenous expression of miR-21 inhibitors decreases miR-21 levels.
Supplementary Methods from Synergistic Activity of Bortezomib and HDACi in Preclinical Models of B-cell Precursor Acute Lymphoblastic Leukemia via Modulation of p53, PI3K/AKT, and NF-κB
Authors: Bastian Lorenz , Hof Jana , Pfau Madlen , Fichtner Iduna , Eckert Cornelia , Henze Günter , Prada Javier , von Stackelberg Arend , Seeger Karl , Shalapour Shabnam
Published: April 2023

PDF file - 47K
Supplementary Figures 1 - 3 from Phase I Study of Aurora A Kinase Inhibitor MLN8237 in Advanced Solid Tumors: Safety, Pharmacokinetics, Pharmacodynamics, and Bioavailability of Two Oral Formulations
Authors: Dees E. Claire , Cohen Roger B. , von Mehren Margaret , Stinchcombe Thomas E. , Liu Hua , Venkatakrishnan Karthik , Manfredi Mark , Fingert Howard , Burris Howard A. , Infante Jeffrey R.
Published: April 2023

PDF file, 584K, Supplementary Figures: S1. MLN8237 dose-escalation schema for relative bioavailability sub-study; S2. Relative bioavailability study schema: MLN8237 ECT versus PIC formulation. S3. Scans showing durable partial response after treatment with MLN8237 in a 52-year-old patient with platinum- and radiation-refractory ovarian cancer.
Supplementary Figure Legend, Table 1 from Targeting FGFR with Dovitinib (TKI258): Preclinical and Clinical Data in Breast Cancer
Authors: André Fabrice , Bachelot Thomas , Campone Mario , Dalenc Florence , Perez-Garcia Jose M. , Hurvitz Sara A. , Turner Nicholas , Rugo Hope , Smith John W. , Deudon Stephanie , Shi Michael , Zhang Yong , Kay Andrea , Graus Porta Diana , Yovine Alejandro , Baselga José
Published: April 2023

PDF file - 61K, Growth Inhibition in FGFR1- and FGFR2-Amplified Cell Lines.
Supplementary Figures 1 and 2 from Downregulation of Hematopoietic MUC1 during Experimental Colitis Increases Tumor-Promoting Myeloid-Derived Suppressor Cells
Authors: Poh Tze Wei , Madsen Cathy S. , Gorman Jessica E. , Marler Ronald J. , Leighton Jonathan A. , Cohen Peter A. , Gendler Sandra J.
Published: April 2023

Supplementary Figures 1 and 2 - PDF file 144K, Supplementary Figure 1: DNA from PBMCs of all engrafted female chimeric mice showed presence of Y chromosome gene. DNA from PBMCs of WT-->WT and KO-->WT mice showed presence of only Muc1 or LacZ gene respectively; Supplementary Figure 2: Treatment with anti Gr1 depleted the level of CD11b+Gr1+ PBMCs
Related Article from New Data Supporting Modified RECIST (mRECIST) for Hepatocellular Carcinoma
Authors: Lencioni Riccardo
Published: April 2023

Related Article from New Data Supporting Modified RECIST (mRECIST) for Hepatocellular Carcinoma
Supplementary Table 5 from Profiling Three-Dimensional Nuclear Telomeric Architecture of Myelodysplastic Syndromes and Acute Myeloid Leukemia Defines Patient Subgroups
Authors: Gadji Macoura , Adebayo Awe Julius , Rodrigues Prerana , Kumar Rajat , Houston Donald S. , Klewes Ludger , Dièye Tandakha Ndiaye , Rego Eduardo Magalhães , Passetto Roberto Falcão , de Oliveira Fábio Morato , Mai Sabine
Published: April 2023

PDF file, 99KB, Telomere parameters of the different 3D-telomere subgroups.
Supplementary Table 4b from Profiling Three-Dimensional Nuclear Telomeric Architecture of Myelodysplastic Syndromes and Acute Myeloid Leukemia Defines Patient Subgroups
Authors: Gadji Macoura , Adebayo Awe Julius , Rodrigues Prerana , Kumar Rajat , Houston Donald S. , Klewes Ludger , Dièye Tandakha Ndiaye , Rego Eduardo Magalhães , Passetto Roberto Falcão , de Oliveira Fábio Morato , Mai Sabine
Published: April 2023

PDF file, 14KB, Telomere parameters according to WPSS classification of MDS.
Supplementary Table 3 from Profiling Three-Dimensional Nuclear Telomeric Architecture of Myelodysplastic Syndromes and Acute Myeloid Leukemia Defines Patient Subgroups
Authors: Gadji Macoura , Adebayo Awe Julius , Rodrigues Prerana , Kumar Rajat , Houston Donald S. , Klewes Ludger , Dièye Tandakha Ndiaye , Rego Eduardo Magalhães , Passetto Roberto Falcão , de Oliveira Fábio Morato , Mai Sabine
Published: April 2023

PDF file, 62KB, Telomere parameters according to cytogenetic risk factor classifications of AML.
Supplementary Table 2 from Profiling Three-Dimensional Nuclear Telomeric Architecture of Myelodysplastic Syndromes and Acute Myeloid Leukemia Defines Patient Subgroups
Authors: Gadji Macoura , Adebayo Awe Julius , Rodrigues Prerana , Kumar Rajat , Houston Donald S. , Klewes Ludger , Dièye Tandakha Ndiaye , Rego Eduardo Magalhães , Passetto Roberto Falcão , de Oliveira Fábio Morato , Mai Sabine
Published: April 2023

PDF file, 64KB, Clinical data of patients with AML diagnosis and cytogenetic karyotypes.
Supplementary table 1 from Altered DNA Methylation Landscapes of Polycomb-Repressed Loci Are Associated with Prostate Cancer Progression and ERG Oncogene Expression in Prostate Cancer
Authors: Kron Ken , Trudel Dominique , Pethe Vaijayanti , Briollais Laurent , Fleshner Neil , van der Kwast Theodorus , Bapat Bharati
Published: April 2023

Supplementary table 1 XLSX file 49K, Significant DMRs in the total GS, GS6 vs. GS7, and GS7 vs. GS8 analyses
Supplementary Tables 1 - 5 from Frequent Mutational Activation of the PI3K-AKT Pathway in Trastuzumab-Resistant Breast Cancer
Authors: Chandarlapaty Sarat , Sakr Rita A. , Giri Dilip , Patil Sujata , Heguy Adriana , Morrow Monica , Modi Shanu , Norton Larry , Rosen Neal , Hudis Clifford , King Tari A.
Published: April 2023

PDF file - 109K, Supplementary Table 1. Changes in HER2 status Supplementary Table 2. Changes in PTEN status Supplementary Table 3. Changes in PIK3CA status Supplementary Table 4. PI3K mutation and PTEN loss are not mutually exclusive Supplementary Table 5. ER/PR status among PI3K activated tumors
Supplementary Figure 2 from Frequent Mutational Activation of the PI3K-AKT Pathway in Trastuzumab-Resistant Breast Cancer
Authors: Chandarlapaty Sarat , Sakr Rita A. , Giri Dilip , Patil Sujata , Heguy Adriana , Morrow Monica , Modi Shanu , Norton Larry , Rosen Neal , Hudis Clifford , King Tari A.
Published: April 2023

PDF file - 1392K, PTEN IHC changes from pre-trastuzumab to post-trastuzumab samples. Depicted are photomicrographs of PTEN change from reduced to loss of expression: a) PTEN expression by IHC in the primary breast invasive carcinoma with reduced nuclear and cytoplasmic staining as compared to the adjacent normal stroma (200X); b) HE staining of the primary lesion (200X); c) PTEN complete loss of expression in the secondary invasive carcinoma with absence of any staining in the lesion as compared to the adjacent normal stroma (200X); d) HE staining of the secondary lesion (200X)
Supplementary Figure 1 from Disrupting Protein NEDDylation with MLN4924 Is a Novel Strategy to Target Cisplatin Resistance in Ovarian Cancer
Authors: Nawrocki Steffan T. , Kelly Kevin R. , Smith Peter G. , Espitia Claudia M. , Possemato Anthony , Beausoleil Sean A. , Milhollen Michael , Blakemore Stephen , Thomas Michael , Berger Allison , Carew Jennifer S.
Published: April 2023

PDF file - 1755K, Supplemental Figure 1: Effects of targeted p65 knockdown on cisplatin sensitivity.
Supplementary Table 2 from Darinaparsin: Solid Tumor Hypoxic Cytotoxin and Radiosensitizer
Authors: Tian Junqiang , Zhao Hongjuan , Nolley Rosalie , Reese Stephen W. , Young Sarah R. , Li Xuejun , Peehl Donna M. , Knox Susan J.
Published: April 2023

PDF file, 65KB, Cancer cells were treated with DPS for 4 hr under normoxia (NO) or hypoxia (HO), and the proliferation was measured by clonogenic assay.
CCR Translation for This Article from A Phase I Study of an Agonist CD40 Monoclonal Antibody (CP-870,893) in Combination with Gemcitabine in Patients with Advanced Pancreatic Ductal Adenocarcinoma
Authors: Beatty Gregory L. , Torigian Drew A. , Chiorean E. Gabriela , Saboury Babak , Brothers Alex , Alavi Abass , Troxel Andrea B. , Sun Weijing , Teitelbaum Ursina R. , Vonderheide Robert H. , O'Dwyer Peter J.
Published: April 2023

CCR Translation for This Article from A Phase I Study of an Agonist CD40 Monoclonal Antibody (CP-870,893) in Combination with Gemcitabine in Patients with Advanced Pancreatic Ductal Adenocarcinoma
Supplementary Figures 1 - 9 from Darinaparsin: Solid Tumor Hypoxic Cytotoxin and Radiosensitizer
Authors: Tian Junqiang , Zhao Hongjuan , Nolley Rosalie , Reese Stephen W. , Young Sarah R. , Li Xuejun , Peehl Donna M. , Knox Susan J.
Published: April 2023

PDF file, 1660KB, S1 Mouse body weight change in response to DPS treatment; S2. DPS did not induce autophagy in HI-LAPC-4 cells; S3: DPS did not induce cell cycle arrest; S4: DPS did not enhance IR-induced DNA damage; S5: DPS activity on solid tumor cells was not dependent on mitochondrial damage; S6: DPS cytotoxicity depends partially on protein synthesis; S7: DPS did not modulate HIF1α protein and transcriptional activity; Fig S8: JNK was activated by DPS, but not required for DPS cytotoxicity; S9: Oncogene RAS and MYC were overexpressed in HI-LAPC-4 and PC-3 cancer cells.
Supplementary Figure Legend from Darinaparsin: Solid Tumor Hypoxic Cytotoxin and Radiosensitizer
Authors: Tian Junqiang , Zhao Hongjuan , Nolley Rosalie , Reese Stephen W. , Young Sarah R. , Li Xuejun , Peehl Donna M. , Knox Susan J.
Published: April 2023

PDF file, 79KB.
Supplementary Figure 4 from miR-187 Is an Independent Prognostic Factor in Breast Cancer and Confers Increased Invasive Potential In Vitro
Authors: Mulrane Laoighse , Madden Stephen F. , Brennan Donal J. , Gremel Gabriela , McGee Sharon F. , McNally Sara , Martin Finian , Crown John P. , Jirström Karin , Higgins Desmond G. , Gallagher William M. , O'Connor Darran P.
Published: April 2023

PDF file - 53K, Recurrence free survival and miR187 expression in cohort 2
Supplementary Materials and Methods from A Purine Scaffold HSP90 Inhibitor BIIB021 Has Selective Activity against KSHV-Associated Primary Effusion Lymphoma and Blocks vFLIP K13-Induced NF-κB
Authors: Gopalakrishnan Ramakrishnan , Matta Hittu , Chaudhary Preet M.
Published: April 2023

PDF file, 149K.
Supplementary Figure 4 from Combined Targeting of STAT3/NF-κB/COX-2/EP4 for Effective Management of Pancreatic Cancer
Authors: Gong Jingjing , Xie Jianping , Bedolla Roble , Rivas Paul , Chakravarthy Divya , Freeman James W. , Reddick Robert , Kopetz Scott , Peterson Amanda , Wang Huamin , Fischer Susan M. , Kumar Addanki P.
Published: April 2023

PDF file - 1660KB, Effects of Stat3 knockdown on Nx-induced proliferation inhibition.
Supplementary Fig. S2 from A Short Treatment with Galactomannan GM-CT-01 Corrects the Functions of Freshly Isolated Human Tumor–Infiltrating Lymphocytes
Authors: Demotte Nathalie , Bigirimana René , Wieërs Grégoire , Stroobant Vincent , Squifflet Jean-Luc , Carrasco Javier , Thielemans Kris , Baurain Jean-François , Van Der Smissen Patrick , Courtoy Pierre J. , van der Bruggen Pierre
Published: April 2023

PDF file 231K, Effect of GM-CT-01 on the capacity of CD8+ TIL to degranulate
Supplementary Figure 3 from Targeting CXCR1/2 Significantly Reduces Breast Cancer Stem Cell Activity and Increases the Efficacy of Inhibiting HER2 via HER2-Dependent and -Independent Mechanisms
Authors: Singh Jagdeep K. , Farnie Gillian , Bundred Nigel J. , Simões Bruno M , Shergill Amrita , Landberg Göran , Howell Sacha J. , Clarke Robert B.
Published: April 2023

PDF file - 56K, Supplementary Figure 3. HER2 siRNA knockdown, specificity and effect on mammosphere formation.
Supplementary References, Methods and Figure Legend from Identification of Transcriptional Subgroups in EGFR-Mutated and EGFR/KRAS Wild-Type Lung Adenocarcinoma Reveals Gene Signatures Associated with Patient Outcome
Authors: Planck Maria , Isaksson Sofi , Veerla Srinivas , Staaf Johan
Published: April 2023

Supplementary References, Methods and Figure Legend - PDF file 160K, Supplementary Information with detailed information about data processing steps and figure legends for supplementary figures
Supplementary Figure 3 from CpG Island Methylator Phenotype–Positive Tumors in the Absence of MLH1 Methylation Constitute a Distinct Subset of Duodenal Adenocarcinomas and Are Associated with Poor Prognosis
Authors: Fu Tao , Pappou Emmanouil P. , Guzzetta Angela A. , Jeschke Jana , Kwak Ruby , Dave Pujan , Hooker Craig M. , Morgan Richard , Baylin Stephen B. , Iacobuzio-Donahue Christine A. , Wolfgang Christopher L. , Ahuja Nita
Published: April 2023

PDF file, 428K, Kaplan-Meier survival estimates of overall survival in 99 patients with duodenal adenocarcinomas by (A) age, (B) stage, and (C) MSI status.
Figure S1 from Identification of Transcriptional Subgroups in EGFR-Mutated and EGFR/KRAS Wild-Type Lung Adenocarcinoma Reveals Gene Signatures Associated with Patient Outcome
Authors: Planck Maria , Isaksson Sofi , Veerla Srinivas , Staaf Johan
Published: April 2023

Figure S1 - PDF file 102K, Identification, characteristics and validation of transcriptional subgroups in EGFR-mutated and EGFRwt/KRASwt tumors
Supplementary Figures from Lactate Dehydrogenase B: A Metabolic Marker of Response to Neoadjuvant Chemotherapy in Breast Cancer
Authors: Dennison Jennifer B. , Molina Jennifer R. , Mitra Shreya , González-Angulo Ana M. , Balko Justin M. , Kuba María G. , Sanders Melinda E. , Pinto Joseph A. , Gómez Henry L. , Arteaga Carlos L. , Brown Robert E. , Mills Gordon B.
Published: April 2023

Supplementary Figures - PDF file 440K, Figure S1. Figure S1. Validation the IHC protocol for LDHB using FFPE MDAMB231 cells with stable knockdown of LDHA or LDHB. Reduced staining for LDHB was detected only in the LDHB knockdown line. Control cells were infected with a non-silencing shRNA. Figure S2. LDHB, when present, substantially contributed to the total LDH activity in cell lines. Figure S3. A, verification of LDHA or LDHB knockdown by LDH activity in stable isogenic cell lines, MDAMB231 and HCC1937. Figure S4. LDHB association with PAM50 intrinsic subtype in primary breast cancers. A, LDHB mRNA expression separated by intrinsic subtype: Perou GSE10893 (8) Figure S5. High LDHB was associated with triple-negative breast cancer. LDHB mRNA expression of HER2 (by IHC/FISH)-negative disease separated by clinical classification Figure S6. LDHB mRNA expression within PAM50 intrinsic subtypes for HR-positive/HER2-negative breast cancers. Figure S7. LDHB mRNA expression within PAM50 intrinsic subtypes for triple-negative breast cancers Figure S8. LDHB mRNA expression was highly associated with cell cycle proliferation marker, CCNB1, for basal-like cancers within the triple-negative group. Figure S9. Association between mRNA expression and copy number for LDHB for the breast invasive carcinoma cohort separated by (A) basal and (B) luminal A/B subtypes for TCGA "manuscript samples" within the cBio Cancer Genomics Portal
Supplementary Figures 1 - 3 from Effective Anti-Neu–Initiated Antitumor Responses Require the Complex Role of CD4+ T Cells
Authors: Mortenson Eric D. , Park SaeGwang , Jiang Zhujun , Wang Shengdian , Fu Yang-Xin
Published: April 2023

PDF file - 45K, Supplemental Figure 1: The percentage of tumor infiltrating CD4+ cells greater than CD8+ cells. Supplemental Figure 2: Anti-CD4 depletion effectively removes CD4+ cells. Supplemental Figure 3: B cells are not required for anti-neu therapy.
Supplementary Methods 2 from Glucocorticoid Receptor Antagonism as a Novel Therapy for Triple-Negative Breast Cancer
Authors: Skor Maxwell N. , Wonder Erin L. , Kocherginsky Masha , Goyal Anju , Hall Ben A. , Cai Yi , Conzen Suzanne D.
Published: April 2023

Supplementary Methods 2 - PDF 64K, Annotated ImageJ macro for measuring GR+ and total cell counts in MDA-MB-231 xenografted mammary gland tumors
Supplementary Methods, Figure Legends, Tables 1 - 2 from CD133+ Tumor Initiating Cells in a Syngenic Murine Model of Pancreatic Cancer Respond to Minnelide
Authors: Banerjee Sulagna , Nomura Alice , Sangwan Veena , Chugh Rohit , Dudeja Vikas , Vickers Selwyn M. , Saluja Ashok
Published: April 2023

PDF file - 124KB, Supplementary Table 1. Tumorigenicity of CD133+ population, CD133 - population and unsorted KPC cells. Supplementary Table 2. Recent therapeutic compounds tested against pancreatic tumor initialing cells.
Supplementary Figure 3 from Glucocorticoid Receptor Antagonism as a Novel Therapy for Triple-Negative Breast Cancer
Authors: Skor Maxwell N. , Wonder Erin L. , Kocherginsky Masha , Goyal Anju , Hall Ben A. , Cai Yi , Conzen Suzanne D.
Published: April 2023

Supplementary Figure 3 - PDF file 83K, Trypan blue dye exclusion analysis of MDA-MB-231, BT-20 and MDA-MB-468 cells treated with dexamethasone +/-mifepristone and paclitaxel
Supplementary Figure 1 from Glucocorticoid Receptor Antagonism as a Novel Therapy for Triple-Negative Breast Cancer
Authors: Skor Maxwell N. , Wonder Erin L. , Kocherginsky Masha , Goyal Anju , Hall Ben A. , Cai Yi , Conzen Suzanne D.
Published: April 2023

Supplementary Figure 1 - PDF file 129K, In vitro analysis of MDA-MB-231, BT-20, and MDA-MB-468 total live cell counts following treatment
Supplementary Figure 2 from CD133+ Tumor Initiating Cells in a Syngenic Murine Model of Pancreatic Cancer Respond to Minnelide
Authors: Banerjee Sulagna , Nomura Alice , Sangwan Veena , Chugh Rohit , Dudeja Vikas , Vickers Selwyn M. , Saluja Ashok
Published: April 2023

PDF file - 1384KB, CD133+ population from human tumor xenografts in SCID mice showed tumor formation.
Supplementary Table S2 from Development of a Colon Cancer GEMM-Derived Orthotopic Transplant Model for Drug Discovery and Validation
Authors: Martin Eric S. , Belmont Peter J. , Sinnamon Mark J. , Richard Larissa Georgeon , Yuan Jing , Coffee Erin M. , Roper Jatin , Lee Lydia , Heidari Pedram , Lunt Sophia Y. , Goel Gautam , Ji Xiadong , Xie Zhi , Xie Tao , Lamb John , Weinrich Scott L. , VanArsdale Todd , Bronson Roderick T. , Xavier Ramnik J. , Vander Heiden Matthew G. , Kan Julie L. C. , Mahmood Umar , Hung Kenneth E.
Published: April 2023

XLS file - 25 KB, Top 5 Ingenuity Pathway Analysis biological functions represented in GEMM AP vs AKP signature
Supplementary Figure S4 from Development of a Colon Cancer GEMM-Derived Orthotopic Transplant Model for Drug Discovery and Validation
Authors: Martin Eric S. , Belmont Peter J. , Sinnamon Mark J. , Richard Larissa Georgeon , Yuan Jing , Coffee Erin M. , Roper Jatin , Lee Lydia , Heidari Pedram , Lunt Sophia Y. , Goel Gautam , Ji Xiadong , Xie Zhi , Xie Tao , Lamb John , Weinrich Scott L. , VanArsdale Todd , Bronson Roderick T. , Xavier Ramnik J. , Vander Heiden Matthew G. , Kan Julie L. C. , Mahmood Umar , Hung Kenneth E.
Published: April 2023

PDF file - 1 MB, Intrasplenic injection of GEMM tumor derived cell lines and tumor growth in the liver
Supplementary Figure S1 from Development of a Colon Cancer GEMM-Derived Orthotopic Transplant Model for Drug Discovery and Validation
Authors: Martin Eric S. , Belmont Peter J. , Sinnamon Mark J. , Richard Larissa Georgeon , Yuan Jing , Coffee Erin M. , Roper Jatin , Lee Lydia , Heidari Pedram , Lunt Sophia Y. , Goel Gautam , Ji Xiadong , Xie Zhi , Xie Tao , Lamb John , Weinrich Scott L. , VanArsdale Todd , Bronson Roderick T. , Xavier Ramnik J. , Vander Heiden Matthew G. , Kan Julie L. C. , Mahmood Umar , Hung Kenneth E.
Published: April 2023

PDF file - 231 KB, Schematic representation of CRC GEMM conditional alleles
Supplementary Figure 1 from Phase I Pharmacokinetic/Pharmacodynamic Study of MLN8237, an Investigational, Oral, Selective Aurora A Kinase Inhibitor, in Patients with Advanced Solid Tumors
Authors: Cervantes Andres , Elez Elena , Roda Desamparados , Ecsedy Jeffrey , Macarulla Teresa , Venkatakrishnan Karthik , Roselló Susana , Andreu Jordi , Jung JungAh , Sanchis-Garcia Juan Manuel , Piera Adelaida , Blasco Inma , Maños Laura , Pérez-Fidalgo José-Alejandro , Fingert Howard , Baselga Jose , Tabernero Josep
Published: April 2023

PDF file, 1635K, Figure S1. MLN8237 dose-escalation and schedule extension schema.
Supplementary Figure 1 from Distinguishing Clinicopathologic Features of Patients with V600E and V600K BRAF-Mutant Metastatic Melanoma
Authors: Menzies Alexander M. , Haydu Lauren E. , Visintin Lydia , Carlino Matteo S. , Howle Julie R. , Thompson John F. , Kefford Richard F. , Scolyer Richard A. , Long Georgina V.
Published: April 2023

PDF file, 53KB, A survival curve of all patients as outlined on page 23 of the paper:Supplementary Figure S1. Overall survival from distant metastasis based on BRAF and inhibitor status for all patients (n=308).
Supplementary Figure 4 from NADPH Oxidases as Therapeutic Targets in Chronic Myelogenous Leukemia
Authors: Sánchez-Sánchez Beatriz , Gutiérrez-Herrero Sara , López-Ruano Guillermo , Prieto-Bermejo Rodrigo , Romo-González Marta , Llanillo Marcial , Pandiella Atanasio , Guerrero Carmen , Miguel Jesús F. San , Sánchez-Guijo Fermín , del Cañizo Consuelo , Hernández-Hernández Angel
Published: April 2023

PDF file - 61KB, Supplementary figure 4. The activity of SHP1 protein tyrosine phosphatase increases after treatment with imatinib, DPI or a combination thereof.
Supplementary Figure 1 Legend from Synergistic Effects of Metformin Treatment in Combination with Gefitinib, a Selective EGFR Tyrosine Kinase Inhibitor, in LKB1 Wild-type NSCLC Cell Lines
Authors: Morgillo Floriana , Sasso Ferdinando Carlo , Della Corte Carminia Maria , Vitagliano Donata , D'Aiuto Elena , Troiani Teresa , Martinelli Erika , De Vita Ferdinando , Orditura Michele , De Palma Raffaele , Ciardiello Fortunato
Published: April 2023

Supplementary Figure 1 Legend - PDF file 52K, Effects on CALU-3, CALU-3 GEF-R, H1299, H1975 and GLC82 cell growth of the combination of metformin and gefitinib. Cell viability was determined using a 3-(4,5 methylthiazol-2-yl)-2,5- diphenyltetrazolium bromide assay. Treatment combinations and sequences are described in Materials and Methods. CI values were calculated according to the Chou and Talalay mathematical model for drug interactions using the Calcusyn software for different fractions affected (fa). CI is a quantitative measure of the degree of interaction between different drugs. If CI = 1, it denotes additivity; if CI > 1, it denotes antagonism; if 1 < CI > 0.7, it denotes slight synergism; if CI = 0.7-0.3, it denotes synergism; if CI < 0.3, it denotes strong synergism. Results are the median of three independent experiments, each done in eight replicate wells for experimental point
Supplementary Figure 2 from NADPH Oxidases as Therapeutic Targets in Chronic Myelogenous Leukemia
Authors: Sánchez-Sánchez Beatriz , Gutiérrez-Herrero Sara , López-Ruano Guillermo , Prieto-Bermejo Rodrigo , Romo-González Marta , Llanillo Marcial , Pandiella Atanasio , Guerrero Carmen , Miguel Jesús F. San , Sánchez-Guijo Fermín , del Cañizo Consuelo , Hernández-Hernández Angel
Published: April 2023

PDF file - 108KB, Supplementary figure 2. Analysis of the interaction of NADPH oxidases inhibitors and BCR-ABL in bone marrow cells from healthy donors.
Supplementary Table 3 from A Targeted RNAi Screen of the Breast Cancer Genome Identifies KIF14 and TLN1 as Genes That Modulate Docetaxel Chemosensitivity in Triple-Negative Breast Cancer
Authors: Singel Stina Mui , Cornelius Crystal , Batten Kimberly , Fasciani Gail , Wright Woodring E. , Lum Lawrence , Shay Jerry W.
Published: April 2023

PDF File - 86K, List of cell lines (from Neve et al. 2006, see text) with clinical annotations for analysis of KIF14 and TLN1 expression within each clinical subtype of breast cancer.
Supplementary Materials and Methods from P-Glycoprotein, CYP3A, and Plasma Carboxylesterase Determine Brain and Blood Disposition of the mTOR Inhibitor Everolimus (Afinitor) in Mice
Authors: Tang Seng Chuan , Sparidans Rolf W. , Cheung Ka Lei , Fukami Tatsuki , Durmus Selvi , Wagenaar Els , Yokoi Tsuyoshi , van Vlijmen Bart J.M. , Beijnen Jos H. , Schinkel Alfred H.
Published: April 2023

PDF file - 117KB
Supplementary Figure 1 from A Targeted RNAi Screen of the Breast Cancer Genome Identifies KIF14 and TLN1 as Genes That Modulate Docetaxel Chemosensitivity in Triple-Negative Breast Cancer
Authors: Singel Stina Mui , Cornelius Crystal , Batten Kimberly , Fasciani Gail , Wright Woodring E. , Lum Lawrence , Shay Jerry W.
Published: April 2023

PDF File - 2103K, Normalization of expression array datasets. Five expression arrays were normalized and pooled (see Methods).
Supplementary Materials and methods from Autophagy Inhibition Augments the Anticancer Effects of Epirubicin Treatment in Anthracycline-Sensitive and -Resistant Triple-Negative Breast Cancer
Authors: Chittaranjan Suganthi , Bortnik Svetlana , Dragowska Wieslawa H. , Xu Jing , Abeysundara Namal , Leung Amy , Go Nancy E. , DeVorkin Lindsay , Weppler Sherry A. , Gelmon Karen , Yapp Donald T. , Bally Marcel B. , Gorski Sharon M.
Published: April 2023

Detailed description of Alamar blue assay, QRT-PCR, transfections, siRNA, western blot analyses, autophagic flux assay, IHC, and associated references.
Supplementary Figure 3 from Autophagy Inhibition Augments the Anticancer Effects of Epirubicin Treatment in Anthracycline-Sensitive and -Resistant Triple-Negative Breast Cancer
Authors: Chittaranjan Suganthi , Bortnik Svetlana , Dragowska Wieslawa H. , Xu Jing , Abeysundara Namal , Leung Amy , Go Nancy E. , DeVorkin Lindsay , Weppler Sherry A. , Gelmon Karen , Yapp Donald T. , Bally Marcel B. , Gorski Sharon M.
Published: April 2023

Pharmacologic inhibition of autophagy sensitizes EPI-sensitive BT549 and EPI-resistant R75 TNBC cells.
Supplementary Table 3 - 4 from Specific Lymphocyte Subsets Predict Response to Adoptive Cell Therapy Using Expanded Autologous Tumor-Infiltrating Lymphocytes in Metastatic Melanoma Patients
Authors: Radvanyi Laszlo G. , Bernatchez Chantale , Zhang Minying , Fox Patricia S. , Miller Priscilla , Chacon Jessica , Wu Richard , Lizee Gregory , Mahoney Sandy , Alvarado Gladys , Glass Michelle , Johnson Valen E. , McMannis John D. , Shpall Elizabeth , Prieto Victor , Papadopoulos Nicholas , Kim Kevin , Homsi Jade , Bedikian Agop , Hwu Wen-Jen , Patel Sapna , Ross Merrick I. , Lee Jeffrey E. , Gershenwald Jeffrey E. , Lucci Anthony , Royal Richard , Cormier Janice N. , Davies Michael A. , Mansaray Rahmatu , Fulbright Orenthial J. , Toth Christopher , Ramachandran Renjith , Wardell Seth , Gonzalez Audrey , Hwu Patrick
Published: April 2023

PDF file - 76k, Table S3. Associations between categorical patient variables and clinical response; Table S4. Associations between continuous variables and clinical response
Supplementary Table 1 from Specific Lymphocyte Subsets Predict Response to Adoptive Cell Therapy Using Expanded Autologous Tumor-Infiltrating Lymphocytes in Metastatic Melanoma Patients
Authors: Radvanyi Laszlo G. , Bernatchez Chantale , Zhang Minying , Fox Patricia S. , Miller Priscilla , Chacon Jessica , Wu Richard , Lizee Gregory , Mahoney Sandy , Alvarado Gladys , Glass Michelle , Johnson Valen E. , McMannis John D. , Shpall Elizabeth , Prieto Victor , Papadopoulos Nicholas , Kim Kevin , Homsi Jade , Bedikian Agop , Hwu Wen-Jen , Patel Sapna , Ross Merrick I. , Lee Jeffrey E. , Gershenwald Jeffrey E. , Lucci Anthony , Royal Richard , Cormier Janice N. , Davies Michael A. , Mansaray Rahmatu , Fulbright Orenthial J. , Toth Christopher , Ramachandran Renjith , Wardell Seth , Gonzalez Audrey , Hwu Patrick
Published: April 2023

PDF file - 58K, Demographics and clinical characteristics of enrolled patients
Supplementary Table 1 from Preclinical and Clinical Studies of Gamma Secretase Inhibitors with Docetaxel on Human Breast Tumors
Authors: Schott Anne F. , Landis Melissa D. , Dontu Gabriela , Griffith Kent A. , Layman Rachel M. , Krop Ian , Paskett Lacey A. , Wong Helen , Dobrolecki Lacey E. , Lewis Michael T. , Froehlich Amber M. , Paranilam Jaya , Hayes Daniel F. , Wicha Max S. , Chang Jenny C.
Published: April 2023

PDF file - 46K, Patient Level Data. This table tabulates chemotherapy cycles received, response and DLT per patient.
Figure S3 from Adrenomedullin Blockade Suppresses Growth of Human Hormone–Independent Prostate Tumor Xenograft in Mice
Authors: Berenguer-Daizé Caroline , Boudouresque Françoise , Bastide Cyrille , Tounsi Asma , Benyahia Zohra , Acunzo Julie , Dussault Nadège , Delfino Christine , Baeza Nathalie , Daniel Laurent , Cayol Mylène , Rossi Dominique , El Battari Assou , Bertin Denis , Mabrouk Kamel , Martin Pierre-Marie , Ouafik L'Houcine
Published: April 2023

PDF file 42K, AM is involved in many functions of PC3 cells in vitro
Supplementary Table 2 from EZH2 Mutations in Follicular Lymphoma from Different Ethnic Groups and Associated Gene Expression Alterations
Authors: Guo Shuangping , Chan John K.C. , Iqbal Javeed , McKeithan Timothy , Fu Kai , Meng Bin , Pan Yi , Cheuk Wah , Luo Donglan , Wang Ruian , Zhang Weiwei , Greiner Timothy C. , Chan Wing C.
Published: April 2023

PDF file - 17KB, Summary of EZH2 mutation studies in FL.
Supplementary Table 2 from Hepatocyte Growth Factor Sensitizes Brain Tumors to c-MET Kinase Inhibition
Authors: Zhang Ying , Farenholtz Kaitlyn E. , Yang Yanzhi , Guessous Fadila , diPierro Charles G. , Calvert Valerie S. , Deng Jianghong , Schiff David , Xin Wenjun , Lee Jae K. , Purow Benjamin , Christensen James , Petricoin Emanuel , Abounader Roger
Published: April 2023

XLSX file - 128K, Reverse Phase Protein Microarray data for the cell lines with high HGF vs. cell lines with low HGF
Supplementary Document 1 from Integrative Analysis of DCE-MRI and Gene Expression Profiles in Construction of a Gene Classifier for Assessment of Hypoxia-Related Risk of Chemoradiotherapy Failure in Cervical Cancer
Authors: Fjeldbo Christina S. , Julin Cathinka H. , Lando Malin , Forsberg Malin F. , Aarnes Eva-Katrine , Alsner Jan , Kristensen Gunnar B. , Malinen Eirik , Lyng Heidi
Published: April 2023

Construction of a hypoxia gene classifier.